The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "extracellular region", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V1A3G7-1" ], "evidence": [ { "id": "R-GGA-5323545", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5323545" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A8V1A3G7", "gene_name": "RYK", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A3G7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3G7" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V1A3G7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3G7" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1A3G7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3G7" }, { "id": "PS50011", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50011" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Protein kinase", "eco_id": "ECO_0000259", "start_pos": 367, "end_pos": 640, "start_aa": "Ile", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1A3G7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3G7" }, { "id": "PS50814", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50814" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "WIF", "eco_id": "ECO_0000259", "start_pos": 80, "end_pos": 208, "start_aa": "Leu", "end_aa": "Cys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.7.10.1", "ec_name": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "2.7.10.1", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1" }, { "id": "2.7.10.1", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.7.10.1" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 153, "end_pos": 155 }, { "start_pos": 188, "end_pos": 190 }, { "start_pos": 192, "end_pos": 194 }, { "start_pos": 196, "end_pos": 198 }, { "start_pos": 224, "end_pos": 226 }, { "start_pos": 306, "end_pos": 308 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A3H7-1", "uniprot_ac": "A0A8V1A3H7", "uniprot_id": "A0A8V1A3H7_CHICK", "mass": { "chemical_mass": 32615.0, "monoisotopic_mass": 32615.0 }, "refseq": { "ac": "XP_015155784", "name": "apolipoprotein F", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015155784" }, "gene_names": [ { "name": "APOF", "type": "recommended", "evidence": [ { "id": "A0A8V1A3H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3H7" } ] }, { "name": "APOF", "type": "synonym", "evidence": [ { "id": "XP_015155784", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015155784" } ] } ], "protein_names": [ { "name": "Apolipoprotein F", "type": "synonym", "evidence": [ { "id": "A0A8V1A3H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3H7/entry#names_and_taxonomy" } ] }, { "name": "apolipoprotein F", "type": "synonym", "evidence": [ { "id": "XP_015155784", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015155784" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052565.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015155784.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015155784", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015155784" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A3H7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3H7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "APOF", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3H7", "locus": { "chromosome": "34", "start_pos": 1502320, "end_pos": 1503473, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010024983", "url": "https://www.ensembl.org/id/ENSGALG00010024983" } ] } } ], "crossref": [ { "id": "A0A8V1A3H7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A3H7", "database": "AlphaFoldDB", "categories": [] }, { "id": "107055401", "url": "https://www.ncbi.nlm.nih.gov/gene/107055401", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026114", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026114", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:107055401", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:107055401", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FTHMAPL", "url": "https://omabrowser.org/oma/group/FTHMAPL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A3H7", "url": "https://www.orthodb.org/?gene=A0A8V1A3H7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15011", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15011", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15011:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15011:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15148", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15148", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-8964041", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8964041", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015155784", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015155784", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1A3H7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3H7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A3H7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3H7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGADSGGYKGAVEGGWGGGTARRRWCGDSGDCEWRPRAATMGRTLLFLLLLLLLLQGRGETATTAPPGGDRGRTAAVRALLAEVAPPLQALRGREVPCGALLPDALPGFSRIPPLPRAMSRASLALALSVAGCGAEAEAAARELYRELSPPAATALLRGLAGLRDVPADRTLPLLSSLARLRQRCTPPRNGTRSGTFRCRREAEDGACSPPGEREAHGVLEWVPGVNAVYNLGSGLYFAFQGCELLASERALQAAEDLGYAALTALTGGGPVAVGIRFGLQPGIKAGVRALYGYFTADGEPPTAPSAHSGPVLVV", "length": 315, "header": "tr|A0A8V1A3H7-1|A0A8V1A3H7_CHICK Isoform 1 of Apolipoprotein F OS=Gallus gallus OX=9031 GN=APOF PE=4 SV=1 CANONICAL=A0A8V1A3H7-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A3H7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3H7/entry#A0A8V1A3H7-1", "sequence": { "sequence": "MGADSGGYKGAVEGGWGGGTARRRWCGDSGDCEWRPRAATMGRTLLFLLLLLLLLQGRGETATTAPPGGDRGRTAAVRALLAEVAPPLQALRGREVPCGALLPDALPGFSRIPPLPRAMSRASLALALSVAGCGAEAEAAARELYRELSPPAATALLRGLAGLRDVPADRTLPLLSSLARLRQRCTPPRNGTRSGTFRCRREAEDGACSPPGEREAHGVLEWVPGVNAVYNLGSGLYFAFQGCELLASERALQAAEDLGYAALTALTGGGPVAVGIRFGLQPGIKAGVRALYGYFTADGEPPTAPSAHSGPVLVV", "length": 315, "header": "tr|A0A8V1A3H7-1|A0A8V1A3H7_CHICK Isoform 1 of Apolipoprotein F OS=Gallus gallus OX=9031 GN=APOF PE=4 SV=1 CANONICAL=A0A8V1A3H7-1" }, "locus": { "chromosome": "34", "start_pos": 1503414, "end_pos": 1502389, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010061009.1", "url": "https://www.ensembl.org/id/ENSGALT00010061009.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010037749.1", "url": "https://www.ensembl.org/id/ENSGALP00010037749.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 303, "start_aa": "Thr", "end_pos": 303, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr303", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:107055401", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:107055401", "resource": "KEGG Pathway" }, { "id": "R-GGA-8964041", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8964041", "resource": "Reactome", "description": "LDL remodeling" } ], "orthologs": [ { "uniprot_canonical_ac": "Q13790-1", "protein_name": "Apolipoprotein F", "gene_name": "APOF", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTGLCGYSAPDMRGLRLIMIPVELLLCYLLLHPVDATSYGKQTNVLMHFPLSLESQTPSSDPLSCQFLHPKSLPGFSHMAPLPKFLVSLALRNALEEAGCQADVWALQLQLYRQGGVNATQVLIQHLRGLQKGRSTERNVSVEALASALQLLAREQQSTGRVGRSLPTEDCENEKEQAVHNVVQLLPGVGTFYNLGTALYYATQNCLGKARERGRDGAIDLGYDLLMTMAGMSGGPMGLAISAALKPALRSGVQQLIQYYQDQKDANISQPETTKEGLRAISDVSDLEETTTLASFISEVVSSAPYWGWAIIKSYDLDPGAGSLEI", "length": 326 }, "evidence": [ { "id": "A0A8V1A3H7", "url": "https://omabrowser.org/oma/group/A0A8V1A3H7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q91V80-1", "protein_name": "Apolipoprotein F", "gene_name": "Apof", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MHSLRLILMSIQLLCYLLLCPVDATSHGEATSVSTVLPPSKLGYQMQTSDKPLSCQMLLPKSLPGFTYMPPVSKFLVGLALRNALEAAGCQAEVWALQLQLYRLGGVEATQALIHHLQELQKSGHTDREVSVDALSSALQLLAWEQPGPKRAKRSISNTDCDNDQEQSVHNVVDLLPAVGTYYNLGTALYYAIKNCSDKAKERGRDGAIDLGYDLLMAMVGASGGPAGAVITAALKPAMKAGVQRLIQYYYDEKEVTTPQPEVTTHQPETGKDATTDIGVVEEIAMSNFVSEVESTTSNWEWPLLKNYGVLAYKR", "length": 315 }, "evidence": [ { "id": "A0A8V1A3H7", "url": "https://omabrowser.org/oma/group/A0A8V1A3H7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A3H7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3H7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cholesterol metabolic process", "id": "GO:0008203", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008203", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A3H7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3H7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 190, "end_pos": 192, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 303 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 190, "end_pos": 192 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A3J0-1", "uniprot_ac": "A0A8V1A3J0", "uniprot_id": "A0A8V1A3J0_CHICK", "mass": { "chemical_mass": 46603.0, "monoisotopic_mass": 46603.0 }, "refseq": { "ac": "XP_040506894", "name": "ammonium transporter Rh type B-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040506894" }, "gene_names": [ { "name": "LOC100858256", "type": "recommended", "evidence": [ { "id": "A0A8V1A3J0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3J0" } ] }, { "name": "LOC100858256", "type": "synonym", "evidence": [ { "id": "XP_040506894", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040506894" } ] } ], "protein_names": [ { "name": "Ammonium transporter AmtB-like domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8V1A3J0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3J0/entry#names_and_taxonomy" } ] }, { "name": "ammonium transporter Rh type B-like", "type": "synonym", "evidence": [ { "id": "XP_040506894", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040506894" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052551.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040506894", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040506894" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A3J0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3J0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC100858256", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3J0", "locus": {} } ], "crossref": [ { "id": "A0A8V1A3J0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A3J0", "database": "AlphaFoldDB", "categories": [] }, { "id": "100858256", "url": "https://www.ncbi.nlm.nih.gov/gene/100858256", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002229", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002229", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024041", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024041", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029020", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029020", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "GPSMYQI", "url": "https://omabrowser.org/oma/group/GPSMYQI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A3J0", "url": "https://www.orthodb.org/?gene=A0A8V1A3J0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11730", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11730", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11730:SF48", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11730:SF48", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00909", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00909", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040506894", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040506894", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1A3J0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3J0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A3J0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3J0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MALPLPASTRCLLPLSLGLFQAALLLFFALFITYDEHSAAPTNSEDVEHAAKQLHSTFPFFQDIQVMLVVGLGLLLAFLPRYGLSALTHNFLLLNVSAQWALMLQGLLHHLQHGKAVLGLHSMLSAEFAAVTVLISAGAVLGRTSPSQLLAMALCEVPIYLASEWLIITRLGVLDVGGTITIHVFACYFGLGVSKTLFGNAKPTVHPKETPTPRSDLLALLGALILWVFWPSFVAVLCQPGDAQHRAILHTLLALSASTITTVLISILLESDGKLSAGHLQNGSLAGGVAIGAVADMHITPAAALALGSLSSLLCILGFQFLTPLLAKKLALQDRCGIHNLHGLPGILGAVASVVAALLAPGDGSEAARHKQAQWQAAGLVVALGGSLFAGMLVGAALRLPCLAPPPEPLCFEDALYFKLQERAEGPPALGGSTEGVPLATKECE", "length": 445, "header": "tr|A0A8V1A3J0-1|A0A8V1A3J0_CHICK Isoform 1 of Ammonium transporter AmtB-like domain-containing protein OS=Gallus gallus OX=9031 GN=LOC100858256 PE=3 SV=1 CANONICAL=A0A8V1A3J0-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A3J0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3J0/entry#A0A8V1A3J0-1", "sequence": { "sequence": "MALPLPASTRCLLPLSLGLFQAALLLFFALFITYDEHSAAPTNSEDVEHAAKQLHSTFPFFQDIQVMLVVGLGLLLAFLPRYGLSALTHNFLLLNVSAQWALMLQGLLHHLQHGKAVLGLHSMLSAEFAAVTVLISAGAVLGRTSPSQLLAMALCEVPIYLASEWLIITRLGVLDVGGTITIHVFACYFGLGVSKTLFGNAKPTVHPKETPTPRSDLLALLGALILWVFWPSFVAVLCQPGDAQHRAILHTLLALSASTITTVLISILLESDGKLSAGHLQNGSLAGGVAIGAVADMHITPAAALALGSLSSLLCILGFQFLTPLLAKKLALQDRCGIHNLHGLPGILGAVASVVAALLAPGDGSEAARHKQAQWQAAGLVVALGGSLFAGMLVGAALRLPCLAPPPEPLCFEDALYFKLQERAEGPPALGGSTEGVPLATKECE", "length": 445, "header": "tr|A0A8V1A3J0-1|A0A8V1A3J0_CHICK Isoform 1 of Ammonium transporter AmtB-like domain-containing protein OS=Gallus gallus OX=9031 GN=LOC100858256 PE=3 SV=1 CANONICAL=A0A8V1A3J0-1" }, "locus": { "chromosome": "20", "start_pos": 9745197, "end_pos": 9743863, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010061035.1", "url": "https://www.ensembl.org/id/ENSGALT00010061035.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010037765.1", "url": "https://www.ensembl.org/id/ENSGALP00010037765.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 212, "start_aa": "Thr", "end_pos": 212, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr212", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "B0UYU0-1", "protein_name": "Rh50-like protein isoform 2", "gene_name": "rh50", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MKKNSTNLRLRLPALIFASEVVIVVLYACFVTYDDHANALLQNNQTRHMENSFYQNYPFFADIQVMIFIGFGCLLAFFRRYGFGGMVFNFLVATFTIQWAILIQGFFQFFYDGKIHLSVLNLINAEFACAVVLISFGAVLGKTSPVQLLIMALLEIPLFGVTEWAVLKYLRINDAGGSILIHIFACYFGLGVTFVLYRPSLNEGHPKVSTSYQSDLLSVMGTLFLWVFWPSFNSALTFKGDDQHRAVLHTFIGLSASTITAFALSSMLSKNGKISMADVQNVTLAGGVTVGASVDMMISPAAAYVLGVMGCFACMLGYKYLSPVLAQKLRIQDQCGIHNLHGLTGLISSLAGICAILLATEETYGPSLYETFSHQAPPEGDPQLMELQQLIPDLEAGLGRSAKEQALFQVAALFGTIAVSAVGGMLTGVVLKLPFLASPSDEQCFDDEVFFTVPSDYDCVNVLSETRKAENE", "length": 472 }, "evidence": [ { "id": "A0A8V1A3J0", "url": "https://omabrowser.org/oma/group/A0A8V1A3J0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "ammonium homeostasis", "id": "GO:0097272", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097272", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A3J0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3J0" } ], "pmid": "" }, { "name": "ammonium transmembrane transport", "id": "GO:0072488", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072488", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A3J0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3J0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A3J0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3J0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "ammonium channel activity", "id": "GO:0008519", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008519", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A3J0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3J0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 282, "end_pos": 284, "annotation": "n_glycosylation_sequon" }, { "start_pos": 95, "end_pos": 97, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1A3J0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3J0" }, { "id": "PF00909", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00909" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ammonium transporter AmtB-like", "eco_id": "ECO_0000259", "start_pos": 24, "end_pos": 398, "start_aa": "Leu", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 212 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 282, "end_pos": 284 }, { "start_pos": 95, "end_pos": 97 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": 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"o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A3J2-1", "uniprot_ac": "A0A8V1A3J2", "uniprot_id": "A0A8V1A3J2_CHICK", "mass": { "chemical_mass": 35540.0, "monoisotopic_mass": 35540.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Transmembrane protein 198", "type": "recommended", "evidence": [ { "id": "A0A8V1A3J2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3J2/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A3J2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3J2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3J2", "locus": {} } ], "crossref": [ { "id": "A0A8V1A3J2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A3J2", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR025256", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025256", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A3J2", "url": "https://www.orthodb.org/?gene=A0A8V1A3J2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31247", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31247", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31247:SF17", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31247:SF17", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13886", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13886", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1A3J2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3J2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A3J2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3J2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEPGAPTEPRCRLEPWQHYEPGPAVLCALGCVLGLLYGCVGHRCFKAIMFTSGLLLGSGTIFLLCYKERVLETRLSLEVSAGIALAIGALCGLVTALLRSVGLFSTGLLLGLLLAVAVLAAAAPLVPPLSPWVLVGVLLGPALLCALLALRWPKALTTLATAVLGAAVVAVCVDYFVEVFGLVLHVSERLRMEAVGQLCWYSWVVLGVWPALSLLGVLLQQRDPQLAPEMTAAAVPPSAGSQMPAELNPLRVQPPPPACPSDTLRVRRVGLELLPELVGPSAGECSPPQTLLGPPLMAVAPLCPSPPQCLEATPERPLCPPPAVPWGAVPPPPHACHFK", "length": 339, "header": "tr|A0A8V1A3J2-1|A0A8V1A3J2_CHICK Isoform 1 of Transmembrane protein 198 OS=Gallus gallus OX=9031 GN= PE=3 SV=1 CANONICAL=A0A8V1A3J2-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A3J2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3J2/entry#A0A8V1A3J2-1", "sequence": { "sequence": "MEPGAPTEPRCRLEPWQHYEPGPAVLCALGCVLGLLYGCVGHRCFKAIMFTSGLLLGSGTIFLLCYKERVLETRLSLEVSAGIALAIGALCGLVTALLRSVGLFSTGLLLGLLLAVAVLAAAAPLVPPLSPWVLVGVLLGPALLCALLALRWPKALTTLATAVLGAAVVAVCVDYFVEVFGLVLHVSERLRMEAVGQLCWYSWVVLGVWPALSLLGVLLQQRDPQLAPEMTAAAVPPSAGSQMPAELNPLRVQPPPPACPSDTLRVRRVGLELLPELVGPSAGECSPPQTLLGPPLMAVAPLCPSPPQCLEATPERPLCPPPAVPWGAVPPPPHACHFK", "length": 339, "header": "tr|A0A8V1A3J2-1|A0A8V1A3J2_CHICK Isoform 1 of Transmembrane protein 198 OS=Gallus gallus OX=9031 GN= PE=3 SV=1 CANONICAL=A0A8V1A3J2-1" }, "locus": { "chromosome": "34", "start_pos": 1328769, "end_pos": 1326173, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010060294.1", "url": "https://www.ensembl.org/id/ENSGALT00010060294.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010037053.1", "url": "https://www.ensembl.org/id/ENSGALP00010037053.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A3J2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3J2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1A3J2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3J2" }, { "id": "PF13886", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13886" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "TM7S3/TM198-like", "eco_id": "ECO_0000259", "start_pos": 27, "end_pos": 220, "start_aa": "Cys", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A3J7-1", "uniprot_ac": "A0A8V1A3J7", "uniprot_id": "A0A8V1A3J7_CHICK", "mass": { "chemical_mass": 53769.0, "monoisotopic_mass": 53769.0 }, "refseq": {}, "gene_names": [ { "name": "DMAP1", "type": "recommended", "evidence": [ { "id": "A0A8V1A3J7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3J7" } ] } ], "protein_names": [ { "name": "DNA methyltransferase 1-associated protein 1", "type": "recommended", "evidence": [ { "id": "A0A8V1A3J7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3J7/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A3J7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3J7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "DMAP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3J7", "locus": { "chromosome": "8", "start_pos": 20140622, "end_pos": 20111293, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010025582", "url": "https://www.ensembl.org/id/ENSGALG00010025582" } ] } } ], "crossref": [ { "id": "A0A8V1A3J7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A3J7", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd11658", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11658", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "424578", "url": "https://www.ncbi.nlm.nih.gov/gene/424578", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR008468", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008468", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027109", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027109", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032563", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032563", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "RNNIQNW", "url": "https://omabrowser.org/oma/group/RNNIQNW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A3J7", "url": "https://www.orthodb.org/?gene=A0A8V1A3J7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AAZ2", "url": "https://www.orthodb.org/?gene=A0A8V1AAZ2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AAZ6", "url": "https://www.orthodb.org/?gene=A0A8V1AAZ6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12855", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12855", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12855:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12855:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05499", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05499", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16282", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16282", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1A3J7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3J7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A3J7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3J7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AAZ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAZ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AAZ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAZ2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AAZ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAZ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AAZ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAZ6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MCHPQELHTDSSSLLSPSPELDRTAAGKASSQAARWRRVQMCGTSWSWGVWSPRTRAPSTRRISSTQIRDAPPLLPSDTTQGYRTVKAKLGSKKVRPWKWMPFTNPARKDGAMFYHWRRAAEEGKDYPFARFNKTVQVPVYSEQEYQMYLHDDAWTKAETDHLFDLARRFDLRFVVIHDRYDHQQFKKRSVEDLKERYYHICAKLANIRAAPGTDLKIPVFDAGHERRRKEQLERLYNRTPEQVAEEEYLIQELRKIETRKKEREKRTQDLQKLITAADTTTEQRRAERKAPKKKLPQKKETEKPAVPETAGIKFPDFKSAGVTLRSQRMKLPSSVGQKKIKALEQMLMELGVDLNPMPTEEIVQMFNELRSDLVLLYELKQAFANCEYELQMLRHRYEALAKAGSIGPLSVEGTHPDGQTGLGIEEGKGDAKDQIIDVVGAPLTPNSVRRKVVGAEQGALRSPTQMP", "length": 468, "header": "tr|A0A8V1A3J7-1|A0A8V1A3J7_CHICK Isoform 1 of DNA methyltransferase 1-associated protein 1 OS=Gallus gallus OX=9031 GN=DMAP1 PE=1 SV=1 CANONICAL=A0A8V1A3J7-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A3J7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3J7/entry#A0A8V1A3J7-1", "sequence": { "sequence": "MCHPQELHTDSSSLLSPSPELDRTAAGKASSQAARWRRVQMCGTSWSWGVWSPRTRAPSTRRISSTQIRDAPPLLPSDTTQGYRTVKAKLGSKKVRPWKWMPFTNPARKDGAMFYHWRRAAEEGKDYPFARFNKTVQVPVYSEQEYQMYLHDDAWTKAETDHLFDLARRFDLRFVVIHDRYDHQQFKKRSVEDLKERYYHICAKLANIRAAPGTDLKIPVFDAGHERRRKEQLERLYNRTPEQVAEEEYLIQELRKIETRKKEREKRTQDLQKLITAADTTTEQRRAERKAPKKKLPQKKETEKPAVPETAGIKFPDFKSAGVTLRSQRMKLPSSVGQKKIKALEQMLMELGVDLNPMPTEEIVQMFNELRSDLVLLYELKQAFANCEYELQMLRHRYEALAKAGSIGPLSVEGTHPDGQTGLGIEEGKGDAKDQIIDVVGAPLTPNSVRRKVVGAEQGALRSPTQMP", "length": 468, "header": "tr|A0A8V1A3J7-1|A0A8V1A3J7_CHICK Isoform 1 of DNA methyltransferase 1-associated protein 1 OS=Gallus gallus OX=9031 GN=DMAP1 PE=1 SV=1 CANONICAL=A0A8V1A3J7-1" }, "locus": { "chromosome": "8", "start_pos": 20137516, "end_pos": 20111849, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010062422.1", "url": "https://www.ensembl.org/id/ENSGALT00010062422.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038595.1", "url": "https://www.ensembl.org/id/ENSGALP00010038595.1" } ] } }, { "isoform_ac": "A0A8V1AAZ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3J7/entry#A0A8V1AAZ2-1", "sequence": { "sequence": "MPSAGAGTAAGQDGGGQSQQSGSEMATGADVRDILELGGVESENTGTINKKDIINSDKKKSKKSSETLTFKRPEGMHREVYALLYSDKKDAPPLLPSDTTQGYRTVKAKLGSKKVRPWKWMPFTNPARKDGAMFYHWRRAAEEGKDYPFARFNKTVQVPVYSEQEYQMYLHDDAWTKAETDHLFDLARRFDLRFVVIHDRYDHQQFKKRSVEDLKERYYHICAKLANIRAAPGTDLKIPVFDAGHERRRKEQLERLYNRTPEQVAEEEYLIQELRKIETRKKEREKRTQDLQKLITAADTTTEQRRAERKAPKKKLPQKKETEKPAVPETAGIKFPDFKSAGVTLRSQRMKLPSSVGQKKIKALEQMLMELGVDLNPMPTEEIVQMFNELRSDLVLLYELKQAFANCEYELQMLRHRYEALAKAGSIGPLSVEGTHPDGQTGLGIEEGKGDAKDQIIDVVGAPLTPNSVRRKVVGAEQGALRSPTQMP", "length": 488, "header": "tr|A0A8V1AAZ2-1|A0A8V1AAZ2_CHICK Computationally mapped isoform of DNA methyltransferase 1-associated protein 1 OS=Gallus gallus OX=9031 GN=DMAP1 PE=1 SV=1 CANONICAL=A0A8V1A3J7-1" }, "locus": { "chromosome": "8", "start_pos": 20137516, "end_pos": 20111426, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010062414.1", "url": "https://www.ensembl.org/id/ENSGALT00010062414.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038589.1", "url": "https://www.ensembl.org/id/ENSGALP00010038589.1" } ] } }, { "isoform_ac": "A0A8V1AAZ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3J7/entry#A0A8V1AAZ6-1", "sequence": { "sequence": "MATGADVRDILELGGVESENTGTINKKDIINSDKKKSKKSSETLTFKRPEGMHREVYALLYSDKKDAPPLLPSDTTQGYRTVKAKLGSKKVRPWKWMPFTNPARKDGAMFYHWRRAAEEGKDYPFARFNKTVQVPVYSEQEYQMYLHDDAWTKAETDHLFDLARRFDLRFVVIHDRYDHQQFKKRSVEDLKERYYHICAKLANIRAAPGTDLKIPVFDAGHERRRKEQLERLYNRTPEQVAEEEYLIQELRKIETRKKEREKRTQDLQKLITAADTTTEQRRAERKAPKKKLPQKKETEKPAVPETAGIKFPDFKSAGVTLRSQRMKLPSSVGQKKIKALEQMLMELGVDLNPMPTEEIVQMFNELRSDLVLLYELKQAFANCEYELQMLRHRYEALAKAGSIGPLSVEGTHPDGQTGLGIEEGKGDAKDQIIDVVGAPLTPNSTVPNFARGDWNGCATQGNGKVINMNL", "length": 470, "header": "tr|A0A8V1AAZ6-1|A0A8V1AAZ6_CHICK Computationally mapped isoform of DNA methyltransferase 1-associated protein 1 OS=Gallus gallus OX=9031 GN=DMAP1 PE=1 SV=1 CANONICAL=A0A8V1A3J7-1" }, "locus": { "chromosome": "8", "start_pos": 20140572, "end_pos": 20111953, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010062420.1", "url": "https://www.ensembl.org/id/ENSGALT00010062420.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038594.1", "url": "https://www.ensembl.org/id/ENSGALP00010038594.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A287B017-1", "protein_name": "DNA methyltransferase 1-associated protein 1", "gene_name": "DMAP1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MATGADVRDILELGGPEGDAASGTISKKDIINPDKKKSKKSSETLTFKRPEGMHREVYALLYSDKKDAPPLLPSDTGQGYRTVKAKLGSKKVRPWKWMPFTNPARKDGAMFFHWRRAAEEGKDYPFARFNKTVQVPVYSEQEYQLYLHDDAWTKAETDHLFDLSRRFDLRFVVIHDRYDHQQFKKRSVEDLKERYYHICAKLANVRAVPGTDLKIPVFDAGHERRRKEQLERLYNRTPEQVAEEEYLLQELRKIEARKKEREKRSQDLQKLITAADTTAEQRRTERKAPKKKLPQKKEAEKPAVPETAGIKFPDFKSAGVTLRSQRMKLPSSVGQKKIKALEQMLLELGVELSPTPTEELVHMFNELRSDLVLLYELKQACANCEYELQMLRHRHEALARAGVLGGPATPASGPTPTPAEPVVPEAGLGPDPSKDSIIDVVGAPLTPNSRKRRESASSSSSVKKAKKP", "length": 468 }, "evidence": [ { "id": "A0A8V1A3J7", "url": "https://omabrowser.org/oma/group/A0A8V1A3J7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3GYS5-1", "protein_name": "DNA methyltransferase 1-associated protein 1", "gene_name": "Dmap1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MATGADVRDILELGGPEGDAASGTISKKDIINPDKKKSKKSSETLTFKRPEGMHREVYALLYSDKKDAPPLLPSDTGQGYRTVKAKLGSKKVRPWKWMPFTNPARKDGAMFFHWRRAAEEGKDYPFARFNKTVQVPVYSEQEYQLYLHDDAWTKAETDHLFDLSRRFDLRFVVIHDRYDHQQFKKRSVEDLKERYYHICAKLANVRAVPGTDLKIPVFDAGHERRRKEQLERLYNRTPEQVAEEEYLLQELRKIEARKKEREKRSQDLQKLITAADTTAEQRRTERKAPKKKLPQKKEAEKPAVPETAGIKFPDFKSAGVTLRSQRMKLPSSVGQKKIKALEQMLLELGVELSPTPTEELVHMFNELRSDLVLLYELKQACANCEYELQMLRHRHEALARAGVLGGPATPAVGTAPASAEPAVSESGLGLDPTKDTIIDVVGAPLTPNSRKRRESASSSSSVKKAKKP", "length": 468 }, "evidence": [ { "id": "A0A8V1A3J7", "url": "https://omabrowser.org/oma/group/A0A8V1A3J7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q568Y6-1", "protein_name": "DNA methyltransferase 1-associated protein 1", "gene_name": "Dmap1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MATGADVRDILELGGPEGDAASGTISKKDIINPDKKKSKKSSETLTFKRPEGMHREVYALLYSDKKDAPPLLPSDTGQGYRTVKAKLGSKKVRPWKWMPFTNPARKDGAMFFHWRRAAEEGKDYPFARFNKTVQVPVYSEQEYQLYLHDDAWTKAETDHLFDLSRRFDLRFVVIHDRYDHQQYKKRSVEDLKERYYHICAKLANVRAVPGTDLKIPVFDAGHERRRKEQLERLYNRTPEQVAEEEYLLQELRKIEARKKEREKRSQDLQKLITAADTTAEQRRTERKAPKKKLPQKKEAEKPAVPETAGIKFPDFKSAGVTLRSQRMKLPSSVGQKKIKALEQMLLELGVELSPTPTEELVHMFNELRSDLVLLYELKQACANCEYELQMLRHRHEALARAGVLGGPATPAVGPTPASAEPTVSESGLGLDPSKDTIIDVVGAPLTPNSRKRRESASSSSSVKKAKKP", "length": 468 }, "evidence": [ { "id": "A0A8V1A3J7", "url": "https://omabrowser.org/oma/group/A0A8V1A3J7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7K3D8-1", "protein_name": "DNA methyltransferase 1-associated protein 1", "gene_name": "DMAP1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSADVRDILDMERANTPEVTRDSFLATKKRNFERTKTASRRPEGMHREVFALLYTDKKDAPPLLPTDTALGIGAGYKETKARLGMKKVRKWEWAPFSNPARNDSAVFHHWKRVTDNSTDYPFAKFNKQLEVPSYTMTEYNAHLRNNINNWSKVQTDHLFDLARRFDLRFIVMADRWNRQQHGTKTVEELKERYYEVVALLAKAKNQTSEKKVFVYDVEHERRRKEQLEKLFKRTTQQVEEENMLINEMKKIEARKKERERKTQDLQKLISQADQQNEHASNTPSTRKYEKKLHKKKVHQQPRPSRVDSVVNAIEIGSSGIKFADLRGSGVSLRSQRMKLPANIGQRKVKALEQAIQEFKVDPAPPPTEDICTSFNELRSDMVLLCELRTALSTCVYEMESLKHQYEAACPGKTLNIPPSLVPIKTEALDNSTN", "length": 433 }, "evidence": [ { "id": "A0A8V1A3J7", "url": "https://omabrowser.org/oma/group/A0A8V1A3J7/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q8VZL6-1", "protein_name": "SWR1-complex protein 4", "gene_name": "SWC4", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MGGTDAKDILGLPKTPLSLTQEKKSRPQKESHRKPDGISREVYALTGGVAPLMPSIDLKRRPPADEKVAWKWLSFTNSARKDDLQLYHWVRVVNDVPPTGDYSFAKYNKSVDILKYTDEEYENHLTDSVWTKEETDQLFEFCQNFDLRFVVIADRFPVSRTVEELKDRYYSVNRALLRARAQSPADVANHPLMKEPYDITRDRERKRALSMVLSQSRHQEKKDAEILAEAKRITEMRLAARRAEEPDVSANENAGLDKADGVVPGRSVSPTSNSQLPATAVAPSTLTMADYASTLASLRMLHVYLRTYGLEQMVQAASSAVGLRTIKRVEQTLQDLGVNLKPKVPTKTVCDEHLELRKEILTLLNLQKQLQYKESEGSSHREGSYAAMPDTPKDRVFAPDPFSFGAERPIKKEQKRKGPGRQADTPSPAHKRPRKLKASDL", "length": 441 }, "evidence": [ { "id": "A0A8V1A3J7", "url": "https://omabrowser.org/oma/group/A0A8V1A3J7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9JI44-1", "protein_name": "DNA methyltransferase 1-associated protein 1", "gene_name": "Dmap1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MATGADVRDILELGGPEGDAASGTISKKDIINPDKKKSKKSSETLTFKRPEGMHREVYALLYSDKKDAPPLLPSDTGQGYRTVKAKLGSKKVRPWKWMPFTNPARKDGAMFFHWRRAAEEGKDYPFARFNKTVQVPVYSEQEYQLYLHDDAWTKAETDHLFDLSRRFDLRFVVIHDRYDHQQFKKRSVEDLKERYYHICAKLANVRAVPGTDLKIPVFDAGHERRRKEQLERLYNRTPEQVAEEEYLLQELRKIEARKKEREKRSQDLQKLITAADTTAEQRRTERKAPKKKLPQKKEAEKPAVPETAGIKFPDFKSAGVTLRSQRMKLPSSVGQKKIKALEQMLLELGVELSPTPTEELVHMFNELRSDLVLLYELKQACANCEYELQMLRHRHEALARAGVLGAPAAAAVGPTPASAEPTVSESGLGLDPTKDTIIDVVGAPLTPNSRKRRESASSSSSVKKAKKP", "length": 468 }, "evidence": [ { "id": "A0A8V1A3J7", "url": "https://omabrowser.org/oma/group/A0A8V1A3J7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NPF5-1", "protein_name": "DNA methyltransferase 1-associated protein 1", "gene_name": "DMAP1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATGADVRDILELGGPEGDAASGTISKKDIINPDKKKSKKSSETLTFKRPEGMHREVYALLYSDKKDAPPLLPSDTGQGYRTVKAKLGSKKVRPWKWMPFTNPARKDGAMFFHWRRAAEEGKDYPFARFNKTVQVPVYSEQEYQLYLHDDAWTKAETDHLFDLSRRFDLRFVVIHDRYDHQQFKKRSVEDLKERYYHICAKLANVRAVPGTDLKIPVFDAGHERRRKEQLERLYNRTPEQVAEEEYLLQELRKIEARKKEREKRSQDLQKLITAADTTAEQRRTERKAPKKKLPQKKEAEKPAVPETAGIKFPDFKSAGVTLRSQRMKLPSSVGQKKIKALEQMLLELGVELSPTPTEELVHMFNELRSDLVLLYELKQACANCEYELQMLRHRHEALARAGVLGGPATPASGPGPASAEPAVTEPGLGPDPKDTIIDVVGAPLTPNSRKRRESASSSSSVKKAKKP", "length": 467 }, "evidence": [ { "id": "A0A8V1A3J7", "url": "https://omabrowser.org/oma/group/A0A8V1A3J7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A3J7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3J7" } ], "pmid": "" }, { "name": "NuA4 histone acetyltransferase complex", "id": "GO:0035267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035267", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A3J7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3J7" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A3J7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3J7" } ], "pmid": "" }, { "name": "Swr1 complex", "id": "GO:0000812", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000812", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A3J7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3J7" } ], "pmid": "" }, { "name": "replication fork", "id": "GO:0005657", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005657", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A3J7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3J7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 8, "go_terms": [ { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A3J7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3J7" } ], "pmid": "" }, { "name": "chromatin remodeling", "id": "GO:0006338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006338", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A3J7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3J7" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A3J7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3J7" } ], "pmid": "" }, { "name": "negative regulation of DNA-templated transcription", "id": "GO:0045892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045892", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A3J7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3J7" } ], "pmid": "" }, { "name": "positive regulation of protein import into nucleus", "id": "GO:0042307", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042307", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A3J7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3J7" } ], "pmid": "" }, { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A3J7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3J7" } ], "pmid": "" }, { "name": "regulation of cell cycle", "id": "GO:0051726", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051726", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A3J7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3J7" } ], "pmid": "" }, { "name": "positive regulation of double-strand break repair via homologous recombination", "id": "GO:1905168", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905168", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A3J7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3J7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "transcription corepressor activity", "id": "GO:0003714", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003714", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A3J7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3J7" } ], "pmid": "" }, { "name": "RNA polymerase II-specific DNA-binding transcription factor binding", "id": "GO:0061629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061629", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A3J7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3J7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 133, "end_pos": 135, "annotation": "n_glycosylation_sequon" }, { "start_pos": 238, "end_pos": 240, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1A3J7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3J7" }, { "id": "PF16282", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16282" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DAMP1 SANT/Myb-like", "eco_id": "ECO_0000259", "start_pos": 127, "end_pos": 205, "start_aa": "Tyr", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1A3J7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3J7" }, { "id": "PF05499", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05499" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DNA methyltransferase 1-associated 1", "eco_id": "ECO_0000259", "start_pos": 246, "end_pos": 404, "start_aa": "Glu", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 133, "end_pos": 135 }, { "start_pos": 238, "end_pos": 240 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A3K1-1", "uniprot_ac": "A0A8V1A3K1", "uniprot_id": "A0A8V1A3K1_CHICK", "mass": { "chemical_mass": 56594.0, "monoisotopic_mass": 56594.0 }, "refseq": { "ac": "NP_001165845", "name": "heat shock factor protein 4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001165845" }, "gene_names": [ { "name": "HSF4", "type": "recommended", "evidence": [ { "id": "A0A8V1A3K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3K1" } ] }, { "name": "HSF4", "type": "synonym", "evidence": [ { "id": "NP_001165845", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001165845" } ] }, { "name": "Hsf4b", "type": "synonym", "evidence": [ { "id": "NP_001165845", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001165845" } ] }, { "name": "cHSF4b", "type": "synonym", "evidence": [ { "id": "NP_001165845", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001165845" } ] } ], "protein_names": [ { "name": "Heat shock transcription factor 4", "type": "synonym", "evidence": [ { "id": "A0A8V1A3K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3K1/entry#names_and_taxonomy" } ] }, { "name": "heat shock factor protein 4", "type": "synonym", "evidence": [ { "id": "NP_001165845", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001165845" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AB510448.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992393 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000247.1. On Dec 3, 2021 this sequence version replaced NP_001165845.2. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001165845", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001165845" } ] }, { "annotation": "As well as altering their basal mRNA levels during the first week post-hatch, thermal manipulation also altered the dynamics of the mRNA expression of heat shock factors, which was associated with improved acquisition of thermotolerance during thermal stress.", "evidence": [ { "database": "RefSeq", "id": "NP_001165845", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001165845" }, { "database": "PubMed", "id": "29917159", "url": "https://glygen.org/publication/PubMed/29917159" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A3K1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3K1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "HSF4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3K1", "locus": { "chromosome": "11", "start_pos": 2497331, "end_pos": 2481438, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010024703", "url": "https://www.ensembl.org/id/ENSGALG00010024703" } ] } } ], "crossref": [ { "id": "A0A8V1A3K1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A3K1", "database": "AlphaFoldDB", "categories": [] }, { "id": "427540", "url": "https://www.ncbi.nlm.nih.gov/gene/427540", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000232", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000232", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010542", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010542", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036388", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036388", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036390", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036390", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:427540", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427540", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ACPGKDV", "url": "https://omabrowser.org/oma/group/ACPGKDV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A3K1", "url": "https://www.orthodb.org/?gene=A0A8V1A3K1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10015", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10015", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10015:SF213", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10015:SF213", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00447", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00447", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF06546", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06546", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001165845", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001165845", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1A3K1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3K1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A3K1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3K1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQDSPGSLVMDGYTSNVPAFLTKLWTLVEDPETNHLICWSTNGTSFHVFDQGRFAKEVLPKYFKHNNMASFVRQLNMYGFRKVVNIEQGGLVKPERDDTEFQHLCFLQGHEHLLEHIKRKVSVVKSEETKMRQEDLSRLLYEVQILKSQQENMECQMQDMKQQNEVLWREVVSLRQNHSQQQKVINKLIQFLFGQLQSSSGSAGIKRKLPLMLDSGLSAPQVSKFSRHLSADALHDAYFIQSPSTEPTSCLHSPAVAAGPIISDVTEASQSSLMNMQSPPDNDREKCLMLIKEEPASPGVKATNEPDIPLSGCRACPEPPVLPVAMVQSVLEGKGSCGVAPPGTSQPPERRGRRTLLDRTDISDPLEGPDWSLEGLQLLLRSQQYGLEPAGLLDVFNPNLPMSECNLAEMEASLSPMQRLTVDLEKNATELNSKVFNPSFSSACPGKDVLLESSQQFLTDRQSVFGNDIISLPESSSLYVPSENMASYLSSVGVQGDIPLNLSSSTDNNQ", "length": 510, "header": "tr|A0A8V1A3K1-1|A0A8V1A3K1_CHICK Isoform 1 of Heat shock transcription factor 4 OS=Gallus gallus OX=9031 GN=HSF4 PE=3 SV=1 CANONICAL=A0A8V1A3K1-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A3K1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3K1/entry#A0A8V1A3K1-1", "sequence": { "sequence": "MQDSPGSLVMDGYTSNVPAFLTKLWTLVEDPETNHLICWSTNGTSFHVFDQGRFAKEVLPKYFKHNNMASFVRQLNMYGFRKVVNIEQGGLVKPERDDTEFQHLCFLQGHEHLLEHIKRKVSVVKSEETKMRQEDLSRLLYEVQILKSQQENMECQMQDMKQQNEVLWREVVSLRQNHSQQQKVINKLIQFLFGQLQSSSGSAGIKRKLPLMLDSGLSAPQVSKFSRHLSADALHDAYFIQSPSTEPTSCLHSPAVAAGPIISDVTEASQSSLMNMQSPPDNDREKCLMLIKEEPASPGVKATNEPDIPLSGCRACPEPPVLPVAMVQSVLEGKGSCGVAPPGTSQPPERRGRRTLLDRTDISDPLEGPDWSLEGLQLLLRSQQYGLEPAGLLDVFNPNLPMSECNLAEMEASLSPMQRLTVDLEKNATELNSKVFNPSFSSACPGKDVLLESSQQFLTDRQSVFGNDIISLPESSSLYVPSENMASYLSSVGVQGDIPLNLSSSTDNNQ", "length": 510, "header": "tr|A0A8V1A3K1-1|A0A8V1A3K1_CHICK Isoform 1 of Heat shock transcription factor 4 OS=Gallus gallus OX=9031 GN=HSF4 PE=3 SV=1 CANONICAL=A0A8V1A3K1-1" }, "locus": { "chromosome": "11", "start_pos": 2496327, "end_pos": 2481637, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010060305.1", "url": "https://www.ensembl.org/id/ENSGALT00010060305.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010037064.1", "url": "https://www.ensembl.org/id/ENSGALP00010037064.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Thermal manipulation during broiler chicken embryogenesis increases basal mRNA levels and alters production dynamics of heat shock proteins 70 and 60 and heat shock factors 3 and 4 during thermal stress.", "journal": "Poultry science", "date": "2018-10-01", "authors": "Al-Zghoul M B", "evidence": [ { "database": "RefSeq", "id": "NP_001165845", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001165845" } ], "reference": [ { "type": "PubMed", "id": "29917159", "url": "https://glygen.org/publication/PubMed/29917159" } ] } ], "pathway": [ { "id": "gga:427540", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427540", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A096MK39-1", "protein_name": "Heat shock transcription factor 4", "gene_name": "Hsf4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQEAPAALPTEPGPSPVPAFLGKLWALVGDPGTDHLIRWSPSGTSFLVSDQSRFAKEVLPQYFKHSNMASFVRQLNMYGFRKVVSIEQGGLLRPERDHVEFQHPSFVRGCEQLLERVRRKVPALRGDDTRWRPEDLGRLLGEVQALRGVQESTEARLQELRQQNEILWREVVTLRQSHSQQHRVIGKLIQCLFGPLQTGPSSTGAKRKLSLMLDEGSACSASAKFNACPVSGALLQDPYFIQSPLPETTVGLSPHRARGPIISDIPEDCPSPEGHRLSPSSAGRRVKGLALLKEEPASPGGDGEAGLALAPNECDFCVTAPPPLPVAVVQAILEGKGSFSPEGPRSIQQPEPRGPREVPDRGTLGLDRGNRSPESLLPPVLLRPPPETVEPMDALGPSLHGREWTLMDLDMELSLMQPLAPERAEAELTVKDLTSSGVGKDHTLGTPLMLDVQADLEGAALSVPGALTLYNATESNASYLDPGASPSSP", "length": 489 }, "evidence": [ { "id": "A0A8V1A3K1", "url": "https://omabrowser.org/oma/group/A0A8V1A3K1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5CZP2-1", "protein_name": "Heat shock factor protein 4", "gene_name": "hsf4", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MQENPGSIGVDGGYASNVPAFLTKLWTLVEDPETNHLICWSATGTSFHVFDQGRFAKEVLPKYFKHNNMASFVRQLNMYGFRKVVNIEQSGLVKPERDDTEFQHLYFLQGHEHLLEHIKRKVSIVKSEETKVRQEDLSKLLYEVQVLRSQQENMEMQMQDMKQQNDVLWREVVSLRQNHTQQQKVMNKLIQFLFSQMQSNSPSTVGMKRKLPLMLDDGCSTPPASKFSHNHSMESLQESFYIQSPSTESASCSTSSVMTGGPIISDVTEIPQSSSMALQMQAEESREKCLMLIKEEPVSPGVQGRAEGVPLGSCEVCAEPPVLPVAMVQSVLEGRGSNLGERRAKRPMLERPEIPDGVENVDMSLEDLQLLLRSHQQSMENNAAAMDQFTFSLPLNEWNFAEMDPNLKSELANALIPAAVSQYMFQGQEGELYPTAGYEEQ", "length": 441 }, "evidence": [ { "id": "A0A8V1A3K1", "url": "https://omabrowser.org/oma/group/A0A8V1A3K1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q9R0L1-1", "protein_name": "Heat shock factor protein 4", "gene_name": "Hsf4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQEAPAALPTEPGPSPVPAFLGKLWALVGDPGTDHLIRWSPSGTSFLVSDQSRFAKEVLPQYFKHSNMASFVRQLNMYGFRKVVSIEQGGLLRPERDHVEFQHPSFVRGREQLLERVRRKVPALRGDDSRWRPEDLSRLLGEVQALRGVQESTEARLQELRQQNEILWREVVTLRQSHSQQHRVIGKLIQCLFGPLQTGPSSTGAKRKLSLMLDEGSACSASAKFNACPVSGALLQDPYFIQSPLPETTLGLSPHRARGPIISDIPEDSPSPEGHRLSPSGGCRRVKGLALLKEEPASPGGDGEAGLALAPNECDFCVTAPPPLPVAVVQAILEGKGSYSPEGPRSVQQPEPRGPREVPDRGTLGLDRGNRSPESLLPPMLLRPAPETLEPVAPVDVLGPSLHGREWTLMDLDMELSLMQPLAPETDEAELTVKELNSSGVGKDHTLGTPLMLDVQADLEGAALSVPGALTLYNVTESNASYLDPGASPSSP", "length": 492 }, "evidence": [ { "id": "A0A8V1A3K1", "url": "https://omabrowser.org/oma/group/A0A8V1A3K1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9ULV5-1", "protein_name": "Heat shock factor protein 4", "gene_name": "HSF4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQEAPAALPTEPGPSPVPAFLGKLWALVGDPGTDHLIRWSPSGTSFLVSDQSRFAKEVLPQYFKHSNMASFVRQLNMYGFRKVVSIEQGGLLRPERDHVEFQHPSFVRGREQLLERVRRKVPALRGDDGRWRPEDLGRLLGEVQALRGVQESTEARLRELRQQNEILWREVVTLRQSHGQQHRVIGKLIQCLFGPLQAGPSNAGGKRKLSLMLDEGSSCPTPAKFNTCPLPGALLQDPYFIQSPLPETNLGLSPHRARGPIISDIPEDSPSPEGTRLSPSSDGRREKGLALLKEEPASPGGDGEAGLALAPNECDFCVTAPPPLPVAVVQAILEGKGSFSPEGPRNAQQPEPGDPREIPDRGPLGLESGDRSPESLLPPMLLQPPQESVEPAGPLDVLGPSLQGREWTLMDLDMELSLMQPLVPERGEPELAVKGLNSPSPGKDPTLGAPLLLDVQAALGGPALGLPGALTIYSTPESRTASYLGPEASPSP", "length": 492 }, "evidence": [ { "id": "A0A8V1A3K1", "url": "https://omabrowser.org/oma/group/A0A8V1A3K1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A3K1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3K1" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A3K1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3K1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A3K1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3K1" } ], "pmid": "" }, { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A3K1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3K1" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A3K1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3K1" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A3K1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3K1" } ], "pmid": "" }, { "name": "core promoter sequence-specific DNA binding", "id": "GO:0001046", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001046", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A3K1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3K1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A3K1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3K1" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A3K1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3K1" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A3K1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3K1" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A3K1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3K1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 177, "end_pos": 179, "annotation": "n_glycosylation_sequon" }, { "start_pos": 427, "end_pos": 429, "annotation": "n_glycosylation_sequon" }, { "start_pos": 42, "end_pos": 44, "annotation": "n_glycosylation_sequon" }, { "start_pos": 501, "end_pos": 503, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1A3K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3K1" }, { "id": "PS00434", "database": "PROSITE", "url": "https://prosite.expasy.org/PS00434" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "HSF-type DNA-binding", "eco_id": "ECO_0000259", "start_pos": 59, "end_pos": 83, "start_aa": "Leu", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 177, "end_pos": 179 }, { "start_pos": 427, "end_pos": 429 }, { "start_pos": 42, "end_pos": 44 }, { "start_pos": 501, "end_pos": 503 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8V1A3L2-1", "uniprot_ac": "A0A8V1A3L2", "uniprot_id": "A0A8V1A3L2_CHICK", "mass": { "chemical_mass": 9683.0, "monoisotopic_mass": 9683.0 }, "refseq": { "ac": "NP_001264635", "name": "otospiralin precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264635" }, "gene_names": [ { "name": "OTOS", "type": "recommended", "evidence": [ { "id": "A0A8V1A3L2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3L2" } ] }, { "name": "OTOS", "type": "synonym", "evidence": [ { "id": "NP_001264635", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264635" } ] } ], "protein_names": [ { "name": "Otospiralin", "type": "synonym", "evidence": [ { "id": "A0A8V1A3L2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3L2/entry#names_and_taxonomy" } ] }, { "name": "otospiralin precursor", "type": "synonym", "evidence": [ { "id": "NP_001264635", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264635" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: CN218894.1, BU119344.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992393, SAMEA103992415 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CN218894.1. On Apr 14, 2013 this sequence version replaced XP_003641785.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001264635", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264635" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A3L2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3L2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "OTOS", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3L2", "locus": { "chromosome": "9", "start_pos": 4880580, "end_pos": 4873363, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010025591", "url": "https://www.ensembl.org/id/ENSGALG00010025591" } ] } } ], "crossref": [ { "id": "A0A8V1A3L2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A3L2", "database": "AlphaFoldDB", "categories": [] }, { "id": "100858447", "url": "https://www.ncbi.nlm.nih.gov/gene/100858447", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR028224", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028224", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:100858447", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100858447", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NTMGYDT", "url": "https://omabrowser.org/oma/group/NTMGYDT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A3L2", "url": "https://www.orthodb.org/?gene=A0A8V1A3L2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A3L8", "url": "https://www.orthodb.org/?gene=A0A8V1A3L8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A8H2", "url": "https://www.orthodb.org/?gene=A0A8V1A8H2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR35073", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR35073", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR35073:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR35073:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15182", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15182", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001264635", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264635", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1A3L2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3L2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A3L2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3L2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A3L8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3L8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A3L8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3L8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A8H2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8H2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A8H2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8H2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKCIGFLFFCMLMSITDARSVLEGDDREPVAMPYWPFSSSDFWSYVEYFRTLGAYNRIAELARALFAQLPAGSHLGLHRPVREE", "length": 84, "header": "tr|A0A8V1A3L2-1|A0A8V1A3L2_CHICK Isoform 1 of Otospiralin OS=Gallus gallus OX=9031 GN=OTOS PE=4 SV=1 CANONICAL=A0A8V1A3L2-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A3L2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3L2/entry#A0A8V1A3L2-1", "sequence": { "sequence": "MKCIGFLFFCMLMSITDARSVLEGDDREPVAMPYWPFSSSDFWSYVEYFRTLGAYNRIAELARALFAQLPAGSHLGLHRPVREE", "length": 84, "header": "tr|A0A8V1A3L2-1|A0A8V1A3L2_CHICK Isoform 1 of Otospiralin OS=Gallus gallus OX=9031 GN=OTOS PE=4 SV=1 CANONICAL=A0A8V1A3L2-1" }, "locus": { "chromosome": "9", "start_pos": 4880100, "end_pos": 4878048, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010062446.1", "url": "https://www.ensembl.org/id/ENSGALT00010062446.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038611.1", "url": "https://www.ensembl.org/id/ENSGALP00010038611.1" } ] } }, { "isoform_ac": "A0A8V1A3L8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3L2/entry#A0A8V1A3L8-1", "sequence": { "sequence": "MLSCTSHSLQSPICVSSSNKLCRSMDLSTGLHQRAPPSKGCAFSHQQLPEPRLFFRNKQLLAEKMKCIGFLFFCMLMSITDARSVLEGDDREPVAMPYWPFSSSDFWSYVEYFRTLGAYNRIAELARALFAQLPAGSHLGLHRPVREE", "length": 148, "header": "tr|A0A8V1A3L8-1|A0A8V1A3L8_CHICK Computationally mapped isoform of Otospiralin OS=Gallus gallus OX=9031 GN=OTOS PE=4 SV=1 CANONICAL=A0A8V1A3L2-1" }, "locus": { "chromosome": "9", "start_pos": 4880100, "end_pos": 4876470, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010062451.1", "url": "https://www.ensembl.org/id/ENSGALT00010062451.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038616.1", "url": "https://www.ensembl.org/id/ENSGALP00010038616.1" } ] } }, { "isoform_ac": "A0A8V1A8H2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3L2/entry#A0A8V1A8H2-1", "sequence": { "sequence": "MPPKNEYHLILQLFFRNKQLLAEKMKCIGFLFFCMLMSITDARSVLEGDDREPVAMPYWPFSSSDFWSYVEYFRTLGAYNRIAELARALFAQLPAGSHLGLHRPVREE", "length": 108, "header": "tr|A0A8V1A8H2-1|A0A8V1A8H2_CHICK Computationally mapped isoform of Otospiralin OS=Gallus gallus OX=9031 GN=OTOS PE=4 SV=1 CANONICAL=A0A8V1A3L2-1" }, "locus": { "chromosome": "9", "start_pos": 4880100, "end_pos": 4877795, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010062440.1", "url": "https://www.ensembl.org/id/ENSGALT00010062440.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038606.1", "url": "https://www.ensembl.org/id/ENSGALP00010038606.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:100858447", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100858447", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "sensory perception of sound", "id": "GO:0007605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007605", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A3L2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3L2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A3M7-1", "uniprot_ac": "A0A8V1A3M7", "uniprot_id": "A0A8V1A3M7_CHICK", "mass": { "chemical_mass": 58702.0, "monoisotopic_mass": 58702.0 }, "refseq": { "ac": "XP_015148305", "name": "E3 ubiquitin-protein ligase TRAIP isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015148305" }, "gene_names": [ { "name": "TRAIP", "type": "recommended", "evidence": [ { "id": "A0A8V1A3M7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3M7" } ] }, { "name": "TRAIP", "type": "synonym", "evidence": [ { "id": "XP_015148305", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015148305" } ] } ], "protein_names": [ { "name": "E3 ubiquitin-protein ligase TRAIP isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015148305", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015148305" } ] }, { "name": "TRAF interacting protein", "type": "synonym", "evidence": [ { "id": "A0A8V1A3M7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3M7/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052543.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015148305.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015148305", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015148305" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A3M7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3M7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TRAIP", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3M7", "locus": { "chromosome": "12", "start_pos": 2715859, "end_pos": 2735264, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027316", "url": "https://www.ensembl.org/id/ENSGALG00010027316" } ] } } ], "crossref": [ { "id": "A0A8V1A3M7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A3M7", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd16480", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16480", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "415927", "url": "https://www.ncbi.nlm.nih.gov/gene/415927", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011016", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011016", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052639", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052639", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "RSKYIQP", "url": "https://omabrowser.org/oma/group/RSKYIQP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A3M7", "url": "https://www.orthodb.org/?gene=A0A8V1A3M7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AFZ5", "url": "https://www.orthodb.org/?gene=A0A8V1AFZ5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46569", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46569", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46569:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46569:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13639", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13639", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-983168", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983168", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015148305", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015148305", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1A3M7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3M7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A3M7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3M7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFZ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFZ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFZ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFZ5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPIRAHCTICSDFFDNARDVAAVPCGHTFHRACLFQWFDTAPSRTCPQCRIQVSKRHIISKLFFDVALEEQTALDAETLQPGSLLKQNQISIQLLLLHWVSKLLSAVVWECDFRAFAKTHVRKSAEFSDLLQNELDKVKAQLSMKEKEKRECQAIVDGLRDTLDVRNATIESLQKVLGETEMLCSSLKKQMKFLEQQQEDNRSSKEEARRLRNKLKTMERIELLLQSQRPEVEEMIREMGVGQAAVEQLAVYCVSLKKEYENLKEARKISSEMTEKQKKELFFVNSKLQKTVSELEKTKEELKSTQKDLKNADKEILSLKKKIDILQDTLKVPSVTRETLSRLVFESPTPVELQQPKLHRPAHSDEINLDDSFDVDTPENQPCRSPFSAAKRQKLDKKRPPVVNLAKKALKETVENWGDDLEDETLKGFLPAFIRNSVFSKKPVSGSLLGPHRNVGKVRMGYDGLGGRTKFIQPTSPTELRPIAVKSKRNVSRPASAAAPERPCSSSRASLDAFLQ", "length": 516, "header": "tr|A0A8V1A3M7-1|A0A8V1A3M7_CHICK Isoform 1 of TRAF interacting protein OS=Gallus gallus OX=9031 GN=TRAIP PE=4 SV=1 CANONICAL=A0A8V1A3M7-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A3M7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3M7/entry#A0A8V1A3M7-1", "sequence": { "sequence": "MPIRAHCTICSDFFDNARDVAAVPCGHTFHRACLFQWFDTAPSRTCPQCRIQVSKRHIISKLFFDVALEEQTALDAETLQPGSLLKQNQISIQLLLLHWVSKLLSAVVWECDFRAFAKTHVRKSAEFSDLLQNELDKVKAQLSMKEKEKRECQAIVDGLRDTLDVRNATIESLQKVLGETEMLCSSLKKQMKFLEQQQEDNRSSKEEARRLRNKLKTMERIELLLQSQRPEVEEMIREMGVGQAAVEQLAVYCVSLKKEYENLKEARKISSEMTEKQKKELFFVNSKLQKTVSELEKTKEELKSTQKDLKNADKEILSLKKKIDILQDTLKVPSVTRETLSRLVFESPTPVELQQPKLHRPAHSDEINLDDSFDVDTPENQPCRSPFSAAKRQKLDKKRPPVVNLAKKALKETVENWGDDLEDETLKGFLPAFIRNSVFSKKPVSGSLLGPHRNVGKVRMGYDGLGGRTKFIQPTSPTELRPIAVKSKRNVSRPASAAAPERPCSSSRASLDAFLQ", "length": 516, "header": "tr|A0A8V1A3M7-1|A0A8V1A3M7_CHICK Isoform 1 of TRAF interacting protein OS=Gallus gallus OX=9031 GN=TRAIP PE=4 SV=1 CANONICAL=A0A8V1A3M7-1" }, "locus": { "chromosome": "12", "start_pos": 2733616, "end_pos": 2716722, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066219.1", "url": "https://www.ensembl.org/id/ENSGALT00010066219.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040485.1", "url": "https://www.ensembl.org/id/ENSGALP00010040485.1" } ] } }, { "isoform_ac": "A0A8V1AFZ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3M7/entry#A0A8V1AFZ5-1", "sequence": { "sequence": "MASVPRSRRTSPGPSGSLFQWFDTAPSRTCPQCRIQVSKRHIISKLFFDVALEEQTALDAETLQNELDKVKAQLSMKEKEKRECQAIVDGLRDTLDVRNATIESLQKVLGETEMLCSSLKKQMKFLEQQQEDNRSSKEEARRLRNKLKTMERIELLLQSQRPEVEEMIREMGVGQAAVEQLAVYCVSLKKEYENLKEARKISSEMTEKQKKELFFVNSKLQKTVSELEKTKEELKSTQKDLKNADKEILSLKKKIDILQDTLKVPSVTRETLSRLVFESPTPVELQQPKLHRPAHSDEINLDDSFDVDTPENQPCRSPFSAAKRQKLDKKRPPVVNLAKKALKETVENWGDDLEDETLKGFLPAFIRNSVFSKKPVSGSLLGPHRNVGKVRMGYDGLGGRTKFIQPTSPTELRPIAVKSKRNVSRPASAAAPERPCSSSRASLDAFLQ", "length": 448, "header": "tr|A0A8V1AFZ5-1|A0A8V1A3M7_CHICK Computationally mapped isoform of TRAF interacting protein OS=Gallus gallus OX=9031 GN=TRAIP PE=4 SV=1 CANONICAL=A0A8V1A3M7-1" }, "locus": { "chromosome": "12", "start_pos": 2734850, "end_pos": 2716722, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066220.1", "url": "https://www.ensembl.org/id/ENSGALT00010066220.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040486.1", "url": "https://www.ensembl.org/id/ENSGALP00010040486.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-983168", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983168", "resource": "Reactome", "description": "Antigen processing: Ubiquitination & Proteasome degradation" } ], "orthologs": [ { "uniprot_canonical_ac": "B1WC52-1", "protein_name": "E3 ubiquitin-protein ligase TRAIP", "gene_name": "Traip", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPIRALCTICSDFFDHSRDVAAIHCGHTFHLQCLIQWFETAPSRTCPQCRIQVGKKTIINKLFFDLAQEEESVLDAEFLKNELDSIKAQLSQKDREKRDSQAIIDTLRDTLEERNATVESLQNALNKAEMLCSTLKKQMKFLEQQRDETKHAQEEARQLKSKMKTMEQIELLLQSQRSEVEEMIRDMGVGQSAVEQLAVYCISLKKEYENLKEARKASGELADRLRKDLASSRSKLKTVNTELDQAKLELRSAQKDLQSADKEITSLRKKLTILQGTLSLPPVTSETVSRLVFESPAPVEMLKPRLHRPPFSDEIDLNATFDVNTPPAQTSSSQHCHPKKLCLERARSPMQDILKIPKVSKSESQLSLGGQRCVGEPDEELAGAFPLFIRNAVRGQKQPNRTTAESRYSTDVVRIGFDGLGGRTKFIQPTDPTIIRPMPVKPKAKSKQKVRIKTVNSASQPKLDTFLCQ", "length": 469 }, "evidence": [ { "id": "A0A8V1A3M7", "url": "https://omabrowser.org/oma/group/A0A8V1A3M7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3H8D9-1", "protein_name": "E3 ubiquitin-protein ligase TRAIP isoform X1", "gene_name": "Traip", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MPIRALCTICSDFFDHSRDVAAIHCGHTFHLQCLIQWFETAPSRTCPQCRIQVGKKAIINKLFFDLAQEEEGVLDAEFLKNELDSIRAQLSQKEREKRDSQTIIDTLRDTLEERNATVESLQNALDKTEMLCSTLKKQMKFLEQQQDETKQAQEEARQLKSKMKTMERIELLLQSQRSEVEEMIRDMGVGQSAVEQLAVYCVSLKKEYENLKEARKASGELADKLKKDLATSKSKLKAVYTELDQAKLELRSTQKDLQSADKEITSLRKKLKMLQETLNLPPVTSETVSRLVFESPAPVEMLHPRLHRPSISDEIDLNATFDVVTPPAQPSSSQHGHPKKLSLERARSPVQDVLKKIPKVSKQEPQLSLGGQRCIGEPDEELAGAFPLFIRNAIRGQKQPNRTTADSRCSTDVVRIGFDGLGGRTKFIQPTDTAIFRPMPVKPKAKSKQKVRIKTVNSSSQPKMDTFLLQ", "length": 470 }, "evidence": [ { "id": "A0A8V1A3M7", "url": "https://omabrowser.org/oma/group/A0A8V1A3M7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "I3LLP4-1", "protein_name": "E3 ubiquitin-protein ligase TRAIP", "gene_name": "TRAIP", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPIRALCTICSDFFDHSRDVAAIHCGHTFHLQCLIQWFETAPSRTCPQCRIQVGKRTIINKLFFDLAQEEESVLDAEFLKNELDNTRALLSQKEKEKRDSQIIIDTLRDTLEERNATVESLQKALDKAEMLCSTLKKQMKYLEQQQDETKQAREEARRLRSKMKTMERIELLLQSQRPEVEEMIREMGVGQSAVEQLAVYCVSLKKEYENLKEARKASGELTDKLKKDLFSSRSKLQTVYSELDQAKLELKSAQKDLQSADKEILSLKKKLMMLQETLNLPPVDSETVNRLVLESPAPVEMLNLKLHRPAFGDDIDLNATFNVDTPPSQPSSIQHGRAKRLFPEEAHSPVQDVPKKMPQGAKQESQLSLGGQRCLGEPDEELADAFPVFIRNAVLGQKQPKRARAEPCRSTDAVRTGFDGLGGRTKFIQPTDTTMIRPLPTKLKLKARAKQRVAARTVLPPSQAKLDSFLS", "length": 471 }, "evidence": [ { "id": "A0A8V1A3M7", "url": "https://omabrowser.org/oma/group/A0A8V1A3M7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q8VIG6-1", "protein_name": "E3 ubiquitin-protein ligase TRAIP", "gene_name": "Traip", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPIRALCTICSDFFDHSRDVAAIHCGHTFHLQCLIQWFETAPSRTCPQCRIQVGKKTIINKLFFDLAQEEENVLDAEFLKNELDSVKAQLSQKDREKRDSQAIIDTLRDTLEERNATVESLQNALNKAEMLCSTLKKQMKFLEQRQDETKQAREEAHRLKCKMKTMEQIELLLQSQRSEVEEMIRDMGVGQSAVEQLAVYCVSLKKEYENLKEARKATGELADRLKKDLVSSRSKLKTLNTELDQAKLELRSAQKDLQSADQEITSLRKKLMILQGTLSLPPATNETVSRLVFESPAPVEMMNPRLHQPPFGDEIDLNTTFDVNTPPTQTSGSQHCLPKKLCLERARSPMQNVLKKVHKVSKPESQLSLGGQRCVGELDEELAGAFPLFIRNAVLGQKQPNRTTAESRCSTDVVRIGFDGLGGRTKFIQPRDTTIIRPVPVKSKAKSKQKVRIKTVSSASQPKLDTFLCQ", "length": 470 }, "evidence": [ { "id": "A0A8V1A3M7", "url": "https://omabrowser.org/oma/group/A0A8V1A3M7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9BWF2-1", "protein_name": "E3 ubiquitin-protein ligase TRAIP", "gene_name": "TRAIP", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPIRALCTICSDFFDHSRDVAAIHCGHTFHLQCLIQWFETAPSRTCPQCRIQVGKRTIINKLFFDLAQEEENVLDAEFLKNELDNVRAQLSQKDKEKRDSQVIIDTLRDTLEERNATVVSLQQALGKAEMLCSTLKKQMKYLEQQQDETKQAQEEARRLRSKMKTMEQIELLLQSQRPEVEEMIRDMGVGQSAVEQLAVYCVSLKKEYENLKEARKASGEVADKLRKDLFSSRSKLQTVYSELDQAKLELKSAQKDLQSADKEIMSLKKKLTMLQETLNLPPVASETVDRLVLESPAPVEVNLKLRRPSFRDDIDLNATFDVDTPPARPSSSQHGYYEKLCLEKSHSPIQDVPKKICKGPRKESQLSLGGQSCAGEPDEELVGAFPIFVRNAILGQKQPKRPRSESSCSKDVVRTGFDGLGGRTKFIQPTDTVMIRPLPVKPKTKVKQRVRVKTVPSLFQAKLDTFLWS", "length": 469 }, "evidence": [ { "id": "A0A8V1A3M7", "url": "https://omabrowser.org/oma/group/A0A8V1A3M7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A3M7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3M7" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A3M7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3M7" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A3M7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3M7" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A3M7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3M7" } ], "pmid": "" }, { "name": "site of DNA damage", "id": "GO:0090734", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090734", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A3M7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3M7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A3M7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3M7" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A3M7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3M7" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A3M7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3M7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "DNA damage response", "id": "GO:0006974", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006974", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A3M7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3M7" } ], "pmid": "" }, { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A3M7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3M7" } ], "pmid": "" }, { "name": "negative regulation of tumor necrosis factor-mediated signaling pathway", "id": "GO:0010804", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010804", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A3M7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3M7" } ], "pmid": "" }, { "name": "negative regulation of interferon-beta production", "id": "GO:0032688", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032688", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A3M7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3M7" } ], "pmid": "" }, { "name": "replication fork processing", "id": "GO:0031297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031297", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A3M7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3M7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 167, "end_pos": 169, "annotation": "n_glycosylation_sequon" }, { "start_pos": 201, "end_pos": 203, "annotation": "n_glycosylation_sequon" }, { "start_pos": 490, "end_pos": 492, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1A3M7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3M7" }, { "id": "PS50089", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50089" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RING-type", "eco_id": "ECO_0000259", "start_pos": 7, "end_pos": 50, "start_aa": "Cys", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 167, "end_pos": 169 }, { "start_pos": 201, "end_pos": 203 }, { "start_pos": 490, "end_pos": 492 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], 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"sequence": { "sequence": "MDLHRAAFKMENSPYLPNPLASPALMVLASTAEASRDASIPCQQPRPFGVPVSADKDVHIPFTNGSYTFASMYHRQGGVPGAFANRDFPPSLLHLHPQFAPPNLDCTPISMLNHSGVGAFRPFASSEDRESYQSAFTPAKRLKNCHDTDSPHLRFSDADGKEYEFGTQLPSSSPGSLKVDETGKKIFAVSGLISDRETSSSPEDRSDRCTIFPLPFMMPRR", "length": 221, "header": "tr|A0A8V1A3M8-1|A0A8V1A3M8_CHICK Isoform 1 of Ring finger protein 220 OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1A3M8-1" }, "locus": { "chromosome": "8", "start_pos": 20262459, "end_pos": 20260958, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010062466.1", "url": "https://www.ensembl.org/id/ENSGALT00010062466.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038626.1", "url": "https://www.ensembl.org/id/ENSGALP00010038626.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 113, "end_pos": 115, 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"total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A3N2-1", "uniprot_ac": "A0A8V1A3N2", "uniprot_id": "A0A8V1A3N2_CHICK", "mass": { "chemical_mass": 82650.0, "monoisotopic_mass": 82650.0 }, "refseq": { "ac": "XP_015142297", "name": "USP6 N-terminal-like protein isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015142297" }, "gene_names": [ { "name": "LOC423110", "type": "recommended", "evidence": [ { "id": "A0A8V1A3N2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3N2" } ] }, { "name": "LOC423110", "type": "synonym", "evidence": [ { "id": "XP_015142297", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015142297" } ] } ], "protein_names": [ { "name": "USP6 N-terminal-like protein", "type": "recommended", "evidence": [ { "id": "A0A8V1A3N2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3N2/entry#names_and_taxonomy" } ] }, { "name": "USP6 N-terminal-like protein isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015142297", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015142297" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052536.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015142297.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015142297", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015142297" } ] }, { "annotation": "Acts as a GTPase-activating protein for RAB43, RAB5A and RAB30. Involved in receptor trafficking. In complex with EPS8 inhibits internalization of EGFR. Involved in retrograde transport from the endocytic pathway to the Golgi apparatus. Involved in the transport of Shiga toxin from early and recycling endosomes to the trans-Golgi network. Required for structural integrity of the Golgi complex.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A3N2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3N2#function" }, { "database": "UniProtKB", "id": "ARBA00094364", "url": "https://www.uniprot.org/uniprotkb/ARBA00094364#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A3N2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3N2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC423110", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3N2", "locus": {} } ], "crossref": [ { "id": "A0A8V1A3N2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A3N2", "database": "AlphaFoldDB", "categories": [] }, { "id": "423110", "url": "https://www.ncbi.nlm.nih.gov/gene/423110", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000195", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000195", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035969", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035969", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050302", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050302", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:423110", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423110", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QVGEHTP", "url": "https://omabrowser.org/oma/group/QVGEHTP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A3N2", "url": "https://www.orthodb.org/?gene=A0A8V1A3N2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47219", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47219", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47219:SF25", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47219:SF25", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00566", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00566", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015142297", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015142297", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1A3N2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3N2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A3N2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3N2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKKDIDTLITQEKAEIIAKYEKGRQEGATIDPWEDADFTLYKVTDRFGFLHEQELPTRTALEEKQKQQEIERVDKWLKMLKKWGKYRNSDKMCRRVYKGIPLQVRGQVWSLLLDVEKMKKENEGKYEQMKQQAKSWSSEIKQIDLDVNRTFRNHIMFRDRYGVKQQALFHVLSAYSVYNTEVSYCQGMSQIAAILLMYLNEEDAFWALAQLLTNQKHAMHGFFIPGFPKLQRFQAHHEQILSKLFPKLKKHMDKEQMTTGIYTTKWFLQCFIDRTPFTLTLRLWDIYILEGERVLTAMAYTILKLHKKRLLKMTLEDLREFLQEKIAASLQYEDDAVIDQLQVSMSELRKMKFDLPPPAKPDEFPRKPLGLELSLNPLATKANAAANGQNGLLGEHPSDRGTAQPPSHQGTAARTPDVPGSQAHEAADSHPHPPQSEGQPTEDVAQRQSPKPSEMQAFPASLEDAVGSGEPTLNAGHGVEHDDHREPHHKPPSPTPSLCSSVGSFHPASNAPVDAPAGEAQPPEQPSSMDHTPDPAACGPSEDQQASSLPGEEATALHRDIPEDIGETQHGVLLLNGMDSKASLPKSASAGELGGLQQSTEMALEQGFTALGSLAPCRPSGSSTPILSESVALARGNSLHTVVKTTTRLHVAQVTEQDLANRRQVALPWPEAAHPLAATSLLPPATSDTGAVQQGTQKPLNALKAPRPPLSPKPKLPPQVSKSLSENNFSPGSLPPARLPKSVTF", "length": 745, "header": "tr|A0A8V1A3N2-1|A0A8V1A3N2_CHICK Isoform 1 of USP6 N-terminal-like protein OS=Gallus gallus OX=9031 GN=LOC423110 PE=4 SV=1 CANONICAL=A0A8V1A3N2-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A3N2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3N2/entry#A0A8V1A3N2-1", "sequence": { "sequence": "MKKDIDTLITQEKAEIIAKYEKGRQEGATIDPWEDADFTLYKVTDRFGFLHEQELPTRTALEEKQKQQEIERVDKWLKMLKKWGKYRNSDKMCRRVYKGIPLQVRGQVWSLLLDVEKMKKENEGKYEQMKQQAKSWSSEIKQIDLDVNRTFRNHIMFRDRYGVKQQALFHVLSAYSVYNTEVSYCQGMSQIAAILLMYLNEEDAFWALAQLLTNQKHAMHGFFIPGFPKLQRFQAHHEQILSKLFPKLKKHMDKEQMTTGIYTTKWFLQCFIDRTPFTLTLRLWDIYILEGERVLTAMAYTILKLHKKRLLKMTLEDLREFLQEKIAASLQYEDDAVIDQLQVSMSELRKMKFDLPPPAKPDEFPRKPLGLELSLNPLATKANAAANGQNGLLGEHPSDRGTAQPPSHQGTAARTPDVPGSQAHEAADSHPHPPQSEGQPTEDVAQRQSPKPSEMQAFPASLEDAVGSGEPTLNAGHGVEHDDHREPHHKPPSPTPSLCSSVGSFHPASNAPVDAPAGEAQPPEQPSSMDHTPDPAACGPSEDQQASSLPGEEATALHRDIPEDIGETQHGVLLLNGMDSKASLPKSASAGELGGLQQSTEMALEQGFTALGSLAPCRPSGSSTPILSESVALARGNSLHTVVKTTTRLHVAQVTEQDLANRRQVALPWPEAAHPLAATSLLPPATSDTGAVQQGTQKPLNALKAPRPPLSPKPKLPPQVSKSLSENNFSPGSLPPARLPKSVTF", "length": 745, "header": "tr|A0A8V1A3N2-1|A0A8V1A3N2_CHICK Isoform 1 of USP6 N-terminal-like protein OS=Gallus gallus OX=9031 GN=LOC423110 PE=4 SV=1 CANONICAL=A0A8V1A3N2-1" }, "locus": { "chromosome": "5", "start_pos": 15661990, "end_pos": 15644801, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010062471.1", "url": "https://www.ensembl.org/id/ENSGALT00010062471.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038631.1", "url": "https://www.ensembl.org/id/ENSGALP00010038631.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 495, "start_aa": "Thr", "end_pos": 495, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr495", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:423110", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423110", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A3N2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3N2" } ], "pmid": "" }, { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A3N2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3N2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A3N2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3N2" } ], "pmid": "" }, { "name": "cytoplasmic vesicle", "id": "GO:0031410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031410", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A3N2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3N2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 148, "end_pos": 150, "annotation": "n_glycosylation_sequon" }, { "start_pos": 728, "end_pos": 730, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1A3N2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3N2" }, { "id": "PS50086", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50086" } ], "ann_type": "Domain_Extent_Annotation", 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"table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A3N6-1", "uniprot_ac": "A0A8V1A3N6", "uniprot_id": "A0A8V1A3N6_CHICK", "mass": { "chemical_mass": 76697.0, "monoisotopic_mass": 76697.0 }, "refseq": {}, "gene_names": [ { "name": "ARHGEF2", "type": "recommended", "evidence": [ { "id": "A0A8V1A3N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3N6" } ] } ], "protein_names": [ { "name": "Rho/Rac guanine nucleotide exchange factor 2", "type": "synonym", "evidence": [ { "id": "A0A8V1A3N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3N6/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A3N6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3N6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ARHGEF2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3N6", "locus": { "chromosome": "25", "start_pos": 482585, "end_pos": 507513, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027310", "url": "https://www.ensembl.org/id/ENSGALG00010027310" } ] } } ], "crossref": [ { "id": "A0A8V1A3N6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A3N6", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00160", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00160", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd20877", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20877", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000219", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000219", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002219", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002219", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035899", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035899", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041020", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041020", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046349", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046349", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051632", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051632", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A3N6", "url": "https://www.orthodb.org/?gene=A0A8V1A3N6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A8J1", "url": "https://www.orthodb.org/?gene=A0A8V1A8J1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AB72", "url": "https://www.orthodb.org/?gene=A0A8V1AB72", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AB77", "url": "https://www.orthodb.org/?gene=A0A8V1AB77", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AFZ9", "url": "https://www.orthodb.org/?gene=A0A8V1AFZ9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13944", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13944", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13944:SF20", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13944:SF20", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00130", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00130", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00621", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00621", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17838", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17838", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1A3N6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3N6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A3N6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3N6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A8J1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8J1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A8J1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8J1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AB72", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB72", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AB72-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB72-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AB77", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB77", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AB77-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB77-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFZ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFZ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFZ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFZ9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGAVHDPSVGGGRLCWVGEGRARGPTVLPHSAALCPMWRSGTAPHVGPTVPCRVPGVGGWCRGVGGVGGDGGGGGGGGHTDVGASIAVAMETGREAPLRAAGPDRHRCAAAMGDPPAGRGAVGGRGAAPGGPAGRGPMGRPTGRCVGQSKERMKEGKEKDARYTNGHLFTTITVSGMTMCFACNKSITAKEALICPTCNVTIHNRCKDTLPNCTKVKQKQQKAALLKNSTALQSVSLRNKGAPRERPNSAVYPSESFRQSLLGPRRGRPSLSLSKSVSTTNIAGTFNEESALGIRRILSQSTDSLNVRNRTVSVESLIEEELEADERDFAADSWSLAVDGAFLQLQRADVMRRQDVIYELMQTELHHVRTLKIMGGVLRRAMLEELQLQPGAVNAVFPCVDELSALHQRFLAQLLQRRRLSLVGGSSKNFVIQRLGDLLVSQFSGQSAEQLRKCYAEFCSKHSAALREYKELLARDKRLQAFVRRTARSPLLRRHGVPECILLVTQRITKYPVLIERILRHSRGDEAEAAELSRALLLVKDLISAINAEVREHELRMRLYDVYRRVDGRAKLQLGCATFGRDELLRRKLLHSGCVLWKPRRDVLLLLMTDVIVFLQEKDQKLSFPTMDKPAVISLHELIVRDVANQEKGLFLLSAAPPEMYELHAASRDERTLWMRLIQQAVSHWEAGGCDGGLRGGGWARG", "length": 702, "header": "tr|A0A8V1A3N6-1|A0A8V1A3N6_CHICK Isoform 1 of Rho/Rac guanine nucleotide exchange factor 2 OS=Gallus gallus OX=9031 GN=ARHGEF2 PE=4 SV=1 CANONICAL=A0A8V1A3N6-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A3N6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3N6/entry#A0A8V1A3N6-1", "sequence": { "sequence": "MGAVHDPSVGGGRLCWVGEGRARGPTVLPHSAALCPMWRSGTAPHVGPTVPCRVPGVGGWCRGVGGVGGDGGGGGGGGHTDVGASIAVAMETGREAPLRAAGPDRHRCAAAMGDPPAGRGAVGGRGAAPGGPAGRGPMGRPTGRCVGQSKERMKEGKEKDARYTNGHLFTTITVSGMTMCFACNKSITAKEALICPTCNVTIHNRCKDTLPNCTKVKQKQQKAALLKNSTALQSVSLRNKGAPRERPNSAVYPSESFRQSLLGPRRGRPSLSLSKSVSTTNIAGTFNEESALGIRRILSQSTDSLNVRNRTVSVESLIEEELEADERDFAADSWSLAVDGAFLQLQRADVMRRQDVIYELMQTELHHVRTLKIMGGVLRRAMLEELQLQPGAVNAVFPCVDELSALHQRFLAQLLQRRRLSLVGGSSKNFVIQRLGDLLVSQFSGQSAEQLRKCYAEFCSKHSAALREYKELLARDKRLQAFVRRTARSPLLRRHGVPECILLVTQRITKYPVLIERILRHSRGDEAEAAELSRALLLVKDLISAINAEVREHELRMRLYDVYRRVDGRAKLQLGCATFGRDELLRRKLLHSGCVLWKPRRDVLLLLMTDVIVFLQEKDQKLSFPTMDKPAVISLHELIVRDVANQEKGLFLLSAAPPEMYELHAASRDERTLWMRLIQQAVSHWEAGGCDGGLRGGGWARG", "length": 702, "header": "tr|A0A8V1A3N6-1|A0A8V1A3N6_CHICK Isoform 1 of Rho/Rac guanine nucleotide exchange factor 2 OS=Gallus gallus OX=9031 GN=ARHGEF2 PE=4 SV=1 CANONICAL=A0A8V1A3N6-1" }, "locus": { "chromosome": "25", "start_pos": 507513, "end_pos": 482588, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066229.1", "url": "https://www.ensembl.org/id/ENSGALT00010066229.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040495.1", "url": "https://www.ensembl.org/id/ENSGALP00010040495.1" } ] } }, { "isoform_ac": "A0A8V1A8J1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3N6/entry#A0A8V1A8J1-1", "sequence": { "sequence": "MGVGGRCRGAGGGVGATQTSAHPSPLPWRRAGKRRSGLPSKERMKEGKEKDARYTNGHLFTTITVSGMTMCFACNKSITAKEALICPTCNVTIHNRCKDTLPNCTKVKQKQQKAALLKNSTALQSVSLRNKGAPRERPNSAVYPSESFRQSLLGPRRGRPSLSLSKSVSTTNIAGTFNEESALGIRRILSQSTDSLNVRNRTVSVESLIEEELEADERDFAADSWSLAVDGAFLQLQRADVMRRQDVIYELMQTELHHVRTLKIMGGVLRRAMLEELQLQPGAVNAVFPCVDELSALHQRFLAQLLQRRRLSLVGGSSKNFVIQRLGDLLVSQFSGQSAEQLRKCYAEFCSKHSAALREYKELLARDKRLQAFVRRTARSPLLRRHGVPECILLVTQRITKYPVLIERILRHSRGADEAEAAELSRALLLVKDLISAINAEVREHELRMRLYDVYRRVDGRAKLGCATFGRDELLRRKLLHSGCVLWKPRRDVLLLLMTDVIVFLQEKDQKLSFPTMDKPAVISLHELIVRDVANQEKGLFLLSAAPPEMYELHAASRDERTLWMRLIQQAVSHWEAGGCDGGLRGGGWARG", "length": 592, "header": "tr|A0A8V1A8J1-1|A0A8V1A8J1_CHICK Computationally mapped isoform of Rho/Rac guanine nucleotide exchange factor 2 OS=Gallus gallus OX=9031 GN=ARHGEF2 PE=4 SV=1 CANONICAL=A0A8V1A3N6-1" }, "locus": { "chromosome": "25", "start_pos": 506770, "end_pos": 482588, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066226.1", "url": "https://www.ensembl.org/id/ENSGALT00010066226.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040492.1", "url": "https://www.ensembl.org/id/ENSGALP00010040492.1" } ] } }, { "isoform_ac": "A0A8V1AB72-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3N6/entry#A0A8V1AB72-1", "sequence": { "sequence": "MGDPKERMKEGKEKDARYTNGHLFTTITVSGMTMCFACNKSITAKEALICPTCNVTIHNRCKDTLPNCTKVKQKQQKAALLKNSTALQSVSLRNKGAPRERPNSAVYPSESFRQSLLGPRRGRPSLSLSKSVSTTNIAGTFNEESALGIRRILSQSTDSLNVRNRTVSVESLIEEELEADERDFAADSWSLAVDGAFLQLQRADVMRRQDVIYELMQTELHHVRTLKIMGGVLRRAMLEELQLQPGAVNAVFPCVDELSALHQRFLAQLLQRRRLSLVGGSSKNFVIQRLGDLLVSQFSGQSAEQLRKCYAEFCSKHSAALREYKELLARDKRLQAFVRRTARSPLLRRHGVPECILLVTQRITKYPVLIERILRHSRGDEAEAAELSRALLLVKDLISAINAEVREHELRMRLYDVYRRVDGRAKLQLGCATFGRDELLRRKLLHSGCVLWKPRRDVLLLLMTDVIVFLQEKDQKLSFPTMDKPAVISLHELIVRDVANQEKGLFLLSAAPPEMYELHAASRDERTLWMRLIQQAVSHWEAGGCDGGLRGGGWARG", "length": 557, "header": "tr|A0A8V1AB72-1|A0A8V1AB72_CHICK Computationally mapped isoform of Rho/Rac guanine nucleotide exchange factor 2 OS=Gallus gallus OX=9031 GN=ARHGEF2 PE=4 SV=1 CANONICAL=A0A8V1A3N6-1" }, "locus": { "chromosome": "25", "start_pos": 506624, "end_pos": 482588, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066223.1", "url": "https://www.ensembl.org/id/ENSGALT00010066223.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040489.1", "url": "https://www.ensembl.org/id/ENSGALP00010040489.1" } ] } }, { "isoform_ac": "A0A8V1AB77-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3N6/entry#A0A8V1AB77-1", "sequence": { "sequence": "CRGAGGWGRCRGAGGAMYGGGGGRKERMKEGKEKDARYTNGHLFTTITVSGMTMCFACNKSITAKEALICPTCNVTIHNRCKDTLPNCTKVKQKQQKAALLKNSTALQSVSLRNKGAPRERPNSAVYPSESFRQSLLGPRRGRPSLSLSKSVSTTNIAGTFNEESALGIRRILSQSTDSLNVRNRTVSVESLIEEELEADERDFAADSWSLAVDGAFLQLQRADVMRRQDVIYELMQTELHHVRTLKIMGGVLRRAMLEELQLQPGAVNAVFPCVDELSALHQRFLAQLLQRRRLSLVGGSSKNFVIQRLGDLLVSQFSGQSAEQLRKCYAEFCSKHSAALREYKELLARDKRLQAFVRRTARSPLLRRHGVPECILLVTQRITKYPVLIERILRHSRGAARRYGLSRALLLVKDLISAINAEVREHELRMRLYDVYRRVDGRAKLQLGCATFGRDELLRRKLLHSGCVLWKPRRDVLLLLMTDVIVFLQEKDQKLSFPTMDKPAVISLHELIVRDVANQEKGLFLLSAAPPEMYELHAASRDERTLWMRLIQQAVSHWEAGGCDGGLRGGGWARG", "length": 576, "header": "tr|A0A8V1AB77-1|A0A8V1AB77_CHICK Computationally mapped isoform of Rho/Rac guanine nucleotide exchange factor 2 OS=Gallus gallus OX=9031 GN=ARHGEF2 PE=4 SV=1 CANONICAL=A0A8V1A3N6-1" }, "locus": { "chromosome": "25", "start_pos": 506968, "end_pos": 482588, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066228.1", "url": "https://www.ensembl.org/id/ENSGALT00010066228.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040494.1", "url": "https://www.ensembl.org/id/ENSGALP00010040494.1" } ] } }, { "isoform_ac": "A0A8V1AFZ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3N6/entry#A0A8V1AFZ9-1", "sequence": { "sequence": "METGREAPLRAAGPDRHRCAAAMGDPPAGRGAVGGRGAAPGGPAGRGPMGRPTGRCVGQSKERMKEGKEKDARYTNGHLFTTITVSGMTMCFACNKSITAKEALICPTCNVTIHNRCKDTLPNCTKVKQKQQKAALLKNSTALQSVSLRNKGAPRERPNSAVYPSESFRQSLLGPRRGRPSLSLSKSVSTTNIAGTFNEESALGIRRILSQSTDSLNVRNRTVSVESLIEEELEADERDFAADSWSLAVDGAFLQLQRADVMRRQDVIYELMQTELHHVRTLKIMGGVLRRAMLEELQLQPGAVNAVFPCVDELSALHQRFLAQLLQRRRLSLVGGSSKNFVIQRLGDLLVSQFSGQSAEQLRKCYAEFCSKHSAALREYKELLARDKRLQAFVRRTARSPLLRRHGVPECILLVTQRITKYPVLIERILRHSRGMERLSLSRALLLVKDLISAINAEVREHELRMRLYDVYRRVDGRAKLQLGCATFGRDELLRRKLLHSGCVLWKPRRDVLLLLMTDVIVFLQEKDQKLSFPTMDKPAVISLHELIVRDVANQEKGLFLLSAAPPEMYELHAASRDERTLWMRLIQQAVSHWEAGGCDGGLRGGGWARG", "length": 611, "header": "tr|A0A8V1AFZ9-1|A0A8V1A3N6_CHICK Computationally mapped isoform of Rho/Rac guanine nucleotide exchange factor 2 OS=Gallus gallus OX=9031 GN=ARHGEF2 PE=4 SV=1 CANONICAL=A0A8V1A3N6-1" }, "locus": { "chromosome": "25", "start_pos": 506690, "end_pos": 482588, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066225.1", "url": "https://www.ensembl.org/id/ENSGALT00010066225.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040491.1", "url": "https://www.ensembl.org/id/ENSGALP00010040491.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 49, "start_aa": "Thr", "end_pos": 49, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr49", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A3N6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3N6" } ], "pmid": "" }, { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A3N6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3N6" } ], "pmid": "" }, { "name": "vesicle", "id": "GO:0031982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031982", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A3N6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3N6" } ], "pmid": "" }, { "name": "ruffle membrane", "id": "GO:0032587", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032587", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A3N6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3N6" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A3N6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3N6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 9, "go_terms": [ { "name": "actin filament organization", "id": "GO:0007015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007015", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A3N6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3N6" } ], "pmid": "" }, { "name": "positive regulation of neuron differentiation", "id": "GO:0045666", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045666", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A3N6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3N6" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A3N6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3N6" } ], "pmid": "" }, { "name": "positive regulation of interleukin-6 production", "id": "GO:0032755", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032755", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A3N6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3N6" } ], "pmid": "" }, { "name": "cell morphogenesis", "id": "GO:0000902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000902", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A3N6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3N6" } ], "pmid": "" }, { "name": "positive regulation of tumor necrosis factor production", "id": "GO:0032760", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032760", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A3N6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3N6" } ], "pmid": "" }, { "name": "negative regulation of microtubule depolymerization", "id": "GO:0007026", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007026", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A3N6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3N6" } ], "pmid": "" }, { "name": "cellular response to muramyl dipeptide", "id": "GO:0071225", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071225", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A3N6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3N6" } ], "pmid": "" }, { "name": "asymmetric neuroblast division", "id": "GO:0055059", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055059", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A3N6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3N6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A3N6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3N6" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A3N6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3N6" } ], "pmid": "" }, { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A3N6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3N6" } ], "pmid": "" }, { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A3N6", "url": 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"Protein Classification", "Other" ] }, { "id": "A0A8V1A3Q1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3Q1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A3Q1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3Q1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AG18", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG18", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AG18-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG18-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "H9KYV4", "url": "https://www.uniprot.org/uniprotkb/H9KYV4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "H9KYV4-1", "url": "https://www.uniprot.org/uniprotkb/H9KYV4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLLGTGGTVGQGTVWPLSLLAFTAATRALSFPRGQLGVTPHPPCQSPHLHPLLRRHVKPKKQHEIRCLGKVLQRLSQATGCDRVVDVGAGQGHLSRFLAFSLGLSVTAVEGDGRLVSLAEHFDQELLRELEKAQARGYSRRLPPSQRHPNTTPDPTDPASLCPRRPQHVAGWLDPQAPGQEFLLAPTPGPALAARNPLAGPVDSEQVLLTGLHACGDLSVALLRHFAHSPQVAAVTSAACCYMKLSTCPEPTAPSLPGYPLSTWVAGLPGHTLSYRAREAACHAVEEYTERLRRDSECLRIHCYRAVLETLIQAADPSKKHLGVQTVKKAHTLSFPECVWGGCPFNPLLASSLGTCGTDMALTHRYARLGLTLVGLDSAAVPLDSESVCAMLCQQHKVVAFFSLVLLLAPLVETLILLDRLLYLREQGGCWQGRGLWSPAGANHPFVHRFPVCPCAPFQPPVLPTQPGAGGRAGATGCSAVRPGQGHPRGRRHGEGWSGALRAGAGLSNAVGTDGCPVAGCEARATIKPGFTQCEVWTERAGGEGAQQDSLHPDNVTQSCQRAPQP", "length": 566, "header": "tr|A0A8V1A3Q1-1|A0A8V1A3Q1_CHICK Isoform 1 of Methyltransferase like 25B OS=Gallus gallus OX=9031 GN=RRNAD1 PE=4 SV=1 CANONICAL=A0A8V1A3Q1-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A3Q1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3Q1/entry#A0A8V1A3Q1-1", "sequence": { "sequence": "MLLGTGGTVGQGTVWPLSLLAFTAATRALSFPRGQLGVTPHPPCQSPHLHPLLRRHVKPKKQHEIRCLGKVLQRLSQATGCDRVVDVGAGQGHLSRFLAFSLGLSVTAVEGDGRLVSLAEHFDQELLRELEKAQARGYSRRLPPSQRHPNTTPDPTDPASLCPRRPQHVAGWLDPQAPGQEFLLAPTPGPALAARNPLAGPVDSEQVLLTGLHACGDLSVALLRHFAHSPQVAAVTSAACCYMKLSTCPEPTAPSLPGYPLSTWVAGLPGHTLSYRAREAACHAVEEYTERLRRDSECLRIHCYRAVLETLIQAADPSKKHLGVQTVKKAHTLSFPECVWGGCPFNPLLASSLGTCGTDMALTHRYARLGLTLVGLDSAAVPLDSESVCAMLCQQHKVVAFFSLVLLLAPLVETLILLDRLLYLREQGGCWQGRGLWSPAGANHPFVHRFPVCPCAPFQPPVLPTQPGAGGRAGATGCSAVRPGQGHPRGRRHGEGWSGALRAGAGLSNAVGTDGCPVAGCEARATIKPGFTQCEVWTERAGGEGAQQDSLHPDNVTQSCQRAPQP", "length": 566, "header": "tr|A0A8V1A3Q1-1|A0A8V1A3Q1_CHICK Isoform 1 of Methyltransferase like 25B OS=Gallus gallus OX=9031 GN=RRNAD1 PE=4 SV=1 CANONICAL=A0A8V1A3Q1-1" }, "locus": { "chromosome": "25", "start_pos": 1041048, "end_pos": 1039196, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066244.1", "url": "https://www.ensembl.org/id/ENSGALT00010066244.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040510.1", "url": "https://www.ensembl.org/id/ENSGALP00010040510.1" } ] } }, { "isoform_ac": "A0A8V1AG18-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3Q1/entry#A0A8V1AG18-1", "sequence": { "sequence": "MLLGTGGTVGQGTVWPLSLLAFTAATRALSFPRGQLGVTPHPPCQSPHLHPLLRRHVKPKKQHEIRCLGKVLQRLSQATGCDRVVDVGAGQGHLSRFLAFSLGLSVTAVEGDGRLVSLAEHFDQELLRELEKAQARGYSRRLPPSQRHPNTTPDPTDPASLCPRRPQHVAGWLDPQAPGQEFLLAPTPGPALAARNPLAGPVDSEQVLLTGLHACGDLSVALLRHFAHSPQVAAVTSAACCYMKLSTCPEPTAPSLPGYPLSTWVAGLPGHTLSYRAREAACHAVEEYTERLRRDSECLRIHCYRAVLETLIQAADPSKKHLGVQTVKKAHTLSFPEYARLGLTLVGLDSAAVPLDSESVCAMLCQQHKVVAFFSLVLLLAPLVETLILLDRLLYLREQGGCWQGRGLWSPAGANHPFVHRFPVCPCAPFQPPVLPTQPGAGGRAGATGCSAVRPGQGHPRGRRHGEGWSGALRAGAGLSNAVGTDGCPVAGCEARATIKPGFTQCEVWTERAGGEGAQQDSLHPDNVTQSCQRAPQP", "length": 538, "header": "tr|A0A8V1AG18-1|A0A8V1A3Q1_CHICK Computationally mapped isoform of Methyltransferase like 25B OS=Gallus gallus OX=9031 GN=RRNAD1 PE=4 SV=1 CANONICAL=A0A8V1A3Q1-1" }, "locus": { "chromosome": "25", "start_pos": 1041048, "end_pos": 1039196, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066245.1", "url": "https://www.ensembl.org/id/ENSGALT00010066245.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040511.1", "url": "https://www.ensembl.org/id/ENSGALP00010040511.1" } ] } }, { "isoform_ac": "H9KYV4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3Q1/entry#H9KYV4-1", "sequence": { "sequence": "MLLGTGGTVGQGTVWPLSLLAFTAATRALSFPRGQLGVTPHPPCQSPHLHPLLRRHVKPKKQHEIRCLGKVLQRLSQATGCDRVVDVGAGQGHLSRFLAFSLGLSVTAVEGDGRLVSLAEHFDQELLRELEKAQARGYSRRLPPSQRHPNTTPDPTDPASLCPRRPQHVAGWLDPQAPGQEFLLAPTPGPALAARNPLAGPVDSEQVLLTGLHACGDLSVALLRHFAHSPQVAAVTSAACCYMKLSTCPEPTAPSLPGYPLSTWVAGLPGHTLSYRAREAACHAVEEYTERLRRDSECLRIHCYRAVLETLIQAADPSKKHLGVQTVKKAHTLSFPEYARLGLTLVGLDSAAVPLDSESVCAMLCQQHKVVAFFSLVLLLAPLVETLILLDRLLYLREQGFQCALVPLFNPRFSPRNLVLVAARVPLDAVLSGLDKDIREDEDTVRGGVEPSGQGQG", "length": 457, "header": "tr|H9KYV4-1|A0A8V1A3Q1_CHICK Computationally mapped isoform of Methyltransferase like 25B OS=Gallus gallus OX=9031 GN=RRNAD1 PE=4 SV=3 CANONICAL=A0A8V1A3Q1-1" }, "locus": { "chromosome": "25", "start_pos": 1040869, "end_pos": 1039196, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066242.1", "url": "https://www.ensembl.org/id/ENSGALT00010066242.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040508.1", "url": "https://www.ensembl.org/id/ENSGALP00010040508.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 187, "start_aa": "Thr", "end_pos": 187, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr187", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "rRNA (adenine-N6,N6-)-dimethyltransferase activity", "id": "GO:0000179", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000179", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A3Q1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3Q1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 150, "end_pos": 152, "annotation": "n_glycosylation_sequon" }, { "start_pos": 555, "end_pos": 557, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1A3Q1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3Q1" }, { "id": "PF13679", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13679" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Methyltransferase", "eco_id": "ECO_0000259", "start_pos": 60, "end_pos": 247, "start_aa": "Lys", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 187 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 150, "end_pos": 152 }, { "start_pos": 555, "end_pos": 557 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A3R6-1", "uniprot_ac": "A0A8V1A3R6", "uniprot_id": "A0A8V1A3R6_CHICK", "mass": { "chemical_mass": 197886.0, "monoisotopic_mass": 197886.0 }, "refseq": {}, "gene_names": [ { "name": "RAB44", "type": "recommended", "evidence": [ { "id": "A0A8V1A3R6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3R6" } ] } ], "protein_names": [ { "name": "RAB44, member RAS onco family", "type": "synonym", "evidence": [ { "id": "A0A8V1A3R6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3R6/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A3R6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3R6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RAB44", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3R6", "locus": {} } ], "crossref": [ { "id": "cd00154", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00154", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001806", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001806", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002048", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002048", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005225", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005225", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050227", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050227", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A3R6", "url": "https://www.orthodb.org/?gene=A0A8V1A3R6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47977", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47977", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00071", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00071", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF27574", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27574", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-6798695", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1A3R6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3R6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A3R6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3R6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAEQRVGSRGRRMGSSRRRQLRRDAGEEPPWAAAVMQRVQEVVQEQRGDTEGFVTRADMQKLQEEVIPCSTEELELLFDGMDAAGSGQLRTEEFTAGLRQFLSSQKVSKEHRRRKTASRRSCLVLASPTWEGTDSEEKKHFAAFMEQLGVDDRWEEQEIWQLWAKLRKDEPQLLGNLEDFLAKMRHRIQEARSKKEALEEALNKRVAEHNQEVQQLCEALEQQIQEERQRMEQESTARSRLHCAVLQRALDARDREVQRLVAAQEELEAQCHSLSSTQRAASAENRQLEENNRALEEQLQHIHAQLQQTHECLRAARAQQRAEEPRDGVEAELPGETPPSLQMSPEQHRSEMGVRLGYHGSEPKRRSTHHVVWEKPAADTNTSRLLSVEEDPFPEFLKEEQFSGQGSLLREMSDAIAALSTQKLQAPGDAAHCPHDDAEPQTGPPGSAPRETHISHEGLEEDLREGRAAAELRAGDGTQAGASAGAQEEGAAQGDSVEGAGQSLEQMERVLSVQGRGAGGEQQVLKEAESPQEALGDSTEMGEQARVGVEGEGWVQGKMKWEKVQLPGEGENMEAVLKAQKVELPVGGSAADVLWVQGEQLELEVPRWVEVQTAAVQGVTEAPNPEKVDGEGSGTVGHCWGEMEGTELQPLSVDGDLGTEQAENIRPDVQLVEEADRAEPELEEGAGAAAVLGEGLSPAEIPAGSPAGGLVLVSAQGLEMEEAEGSPAESLLHGIPSPEALRDGLDDTAIHLREDAENGGQEPAEPGLLNQPLCELQGEEARQAEGTAAELSLQDKAVSLELLEALSGDTHVQLIAELGEMEESLEAALQPLSVAGDLGTEQAENIGPDMQLVEEADRAEPELEEGAGAAAVLGEGLSPAEIAAGSPAGGLVLVSAQGLETEEAEGSPTKTLLHGIPSPEALRDGLDDTAIHLSEDAEDGGQEPAEPGLLSQPVCELQETGDGQAEGAAAELSLQDKAVSLELLEALSGDTHVQLIAELGEMEESLEAALQPLSVAGDLGTEQAENMGPDVQLVEEADRAELQSLYLGHQPHSEQAESMGPEVQLVGEVGKPELVEIEGEEDSQVDMQLQWGPSQEVPLGGGGHTAVQLTQEVEDEGQDVEHLKEERGMEVVQEEGTGKDELVLVSAQGLEMEEAEGSPAESLLHGIPSPEASRDGLDDTAIHVREDAEDGGQELAEPGLLSQPLCELQGEEARHAEGAAAELSPQEKAVSLELLEGLSGDTHVQLIAELGEMEESLEAALQPLNVAGDLGTEQAENMGPDMQLVEEADRAEPELEEGAGAAAVLGEGLSPAEIAAGSPAGGLVLVSAQELEGKETESLVQLEELTLPYGDSTGADGKPLCSVGLWEVAENPAVGLEAAPCMADNTDVWNRNVEPILHPEYAAAAGHAHPAAGLVAASGPELQILEETQRERADAEGRPLDGARGLEVVQGARLEAEARISVAAQHLELKQGRDASAATLASPVSEVPLQISTLNLDVMMQEDVLIPDVQLVGGSGQAAQRQLQEQVSAQADKGRLHAAPQQPQKPPGVMEAEQAAAGPAETPKQEVPPASALHTGIQQGGDAAEDLSGMALGDSPLVEAVSSMVELSGGQREELNVEKKQEMEQKMSLGGKPSPGEPEAVTVNGAEAAPKDSVEPDHLYNVLFVGDSNVGKTSFLYRLHADTFNPHLAATVGLDYQVKNLMVDNRHFALRMWDSAGQERYHSVTKQFFRKADGVVLMYDITSQYSFADVRYWLSCIQEGAEDGITVLLLGNKTDCAAERQVPTQEGERLAQEHQLLFYECSAASGHNVIESIVSLVRALKVCEDQLRNKAEEVPKVPQKKKGCCW", "length": 1846, "header": "tr|A0A8V1A3R6-1|A0A8V1A3R6_CHICK Isoform 1 of RAB44, member RAS onco family OS=Gallus gallus OX=9031 GN=RAB44 PE=4 SV=1 CANONICAL=A0A8V1A3R6-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A3R6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3R6/entry#A0A8V1A3R6-1", "sequence": { "sequence": 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"https://www.uniprot.org/uniprotkb/A0A8V1A3S6/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A3S6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3S6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3S6", "locus": {} } ], "crossref": [ { "id": "A0A8V1A3S6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A3S6", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR013106", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013106", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PF07686", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07686", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1A3S6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3S6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A3S6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3S6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQCLESFKGLGFWKRSKLLCKCISACVAGLTRGNPQKEFFSEMSTTAGQHVVLPCPYNTEYSYRTLNFFWYHQLLGSSFEHALEAFGSSGDNKFCDHRFSVMVYENKMSSSSLSAGVEHN", "length": 120, "header": "tr|A0A8V1A3S6-1|A0A8V1A3S6_CHICK Isoform 1 of Immunoglobulin V-set domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1A3S6-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A3S6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3S6/entry#A0A8V1A3S6-1", "sequence": { "sequence": "MQCLESFKGLGFWKRSKLLCKCISACVAGLTRGNPQKEFFSEMSTTAGQHVVLPCPYNTEYSYRTLNFFWYHQLLGSSFEHALEAFGSSGDNKFCDHRFSVMVYENKMSSSSLSAGVEHN", "length": 120, "header": "tr|A0A8V1A3S6-1|A0A8V1A3S6_CHICK Isoform 1 of Immunoglobulin V-set domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1A3S6-1" }, "locus": { "chromosome": "27", "start_pos": 406517, "end_pos": 405419, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010062557.1", "url": "https://www.ensembl.org/id/ENSGALT00010062557.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038677.1", "url": "https://www.ensembl.org/id/ENSGALP00010038677.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1A3S6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3S6" }, { "id": "PF07686", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07686" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Immunoglobulin V-set", "eco_id": "ECO_0000259", "start_pos": 42, "end_pos": 103, "start_aa": "Glu", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A659-1", "uniprot_ac": "A0A8V1A659", "uniprot_id": "A0A8V1A659_CHICK", "mass": { "chemical_mass": 43905.0, "monoisotopic_mass": 43905.0 }, "refseq": { "ac": "XP_015154385", "name": "bombesin receptor-activated protein C6orf89 homolog isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015154385" }, "gene_names": [ { "name": "C6orf89", "type": "recommended", "evidence": [ { "id": "A0A8V1A659", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A659" } ] }, { "name": "C26H6orf89", "type": "synonym", "evidence": [ { "id": "XP_015154385", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015154385" } ] }, { "name": "C6orf89", "type": "synonym", "evidence": [ { "id": "XP_015154385", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015154385" } ] } ], "protein_names": [ { "name": "C6orf89 homolog", "type": "synonym", "evidence": [ { "id": "A0A8V1A659", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A659/entry#names_and_taxonomy" } ] }, { "name": "bombesin receptor-activated protein C6orf89 homolog isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015154385", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015154385" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 4% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052557.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015154385.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015154385", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015154385" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A659", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A659" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "C6orf89", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A659", "locus": { "chromosome": "26", "start_pos": 1672869, "end_pos": 1652179, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010025637", "url": "https://www.ensembl.org/id/ENSGALG00010025637" } ] } } ], "crossref": [ { "id": "A0A8V1A659", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A659", "database": "AlphaFoldDB", "categories": [] }, { "id": "419817", "url": "https://www.ncbi.nlm.nih.gov/gene/419817", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR038757", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038757", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "FMAKGTE", "url": "https://omabrowser.org/oma/group/FMAKGTE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A3T0", "url": "https://www.orthodb.org/?gene=A0A8V1A3T0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A659", "url": "https://www.orthodb.org/?gene=A0A8V1A659", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR35259", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR35259", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR35259:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR35259:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF28222", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF28222", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015154385", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015154385", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1A3T0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3T0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A3T0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3T0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A659", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A659", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A659-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A659-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAILGSPRWPRCGGGMQAPAWRWCTQRWACCPAWKSSPCAALSGLPAGMEIEAAFPFSRDFLSEAMELSANELSIYDKLSETIDLVRQTGHQCGMSEKAIEKFIKQLLERNEPQRGPPRYPVLAAIYKGLLTLGLVLLTVYFVIQPYSPLPPEAPLSRAHAWGSLIGHIRLLSLPIAKKYMLEKCQDWWAAGCRQNTSTLPANCTACSAVKSFQIVTDFGQLSEKLQRSQPFLIKTGQSLSYEELKHFQSQDPELADIIIEENSSELWSCLPRQSFPFFLPWNRSVNRTQILQEFFPTSSLLSFPKTVSLENCFLIRHPDLGNKSYSLHSLFVVGSGHLTLTVAPLDKCRGHCEMFKVDLEAGDLGYASMDYWMMSFVAKGTEPAVVCYGAAS", "length": 393, "header": "tr|A0A8V1A659-1|A0A8V1A659_CHICK Isoform 1 of C6orf89 homolog OS=Gallus gallus OX=9031 GN=C6orf89 PE=4 SV=1 CANONICAL=A0A8V1A659-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A3T0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A659/entry#A0A8V1A3T0-1", "sequence": { "sequence": "MPCALLTRGKGPCLGEVTVHNDVLTKPAFGQLCQPMRLLRDFLSEAMELSANELSIYDKLSETIDLVRQTGHQCGMSEKAIEKFIKQLLERNEPQRGPPRYPVLAAIYKGLLTLGLVLLTVYFVIQPYSPLPPEAPLSRAHAWGSLIGHIRLLSLPIAKKYMLEKCQDWWAAGCRQNTSTLPANCTACSAVKSFQIVTDFGQLSEKLQRSQPFLIKTGQSLSYEELKHFQSQDPELADIIIEENSSELWSCLPRQSFPFFLPWNRSVNRTQILQEFFPTSSLLSFPKTVSLENCFLIRHPDLGNKSYSLHSLFVVGSGHLTLTVAPLDKCRGHCEMFKVDLEAGDLGYASMDYWMMSFVAKGTEPAVVCYGAAS", "length": 374, "header": "tr|A0A8V1A3T0-1|A0A8V1A659_CHICK Computationally mapped isoform of C6orf89 homolog OS=Gallus gallus OX=9031 GN=C6orf89 PE=4 SV=1 CANONICAL=A0A8V1A659-1" }, "locus": { "chromosome": "26", "start_pos": 1668722, "end_pos": 1653637, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010062569.1", "url": "https://www.ensembl.org/id/ENSGALT00010062569.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038682.1", "url": "https://www.ensembl.org/id/ENSGALP00010038682.1" } ] } }, { "isoform_ac": "A0A8V1A659-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A659/entry#A0A8V1A659-1", "sequence": { "sequence": "MAILGSPRWPRCGGGMQAPAWRWCTQRWACCPAWKSSPCAALSGLPAGMEIEAAFPFSRDFLSEAMELSANELSIYDKLSETIDLVRQTGHQCGMSEKAIEKFIKQLLERNEPQRGPPRYPVLAAIYKGLLTLGLVLLTVYFVIQPYSPLPPEAPLSRAHAWGSLIGHIRLLSLPIAKKYMLEKCQDWWAAGCRQNTSTLPANCTACSAVKSFQIVTDFGQLSEKLQRSQPFLIKTGQSLSYEELKHFQSQDPELADIIIEENSSELWSCLPRQSFPFFLPWNRSVNRTQILQEFFPTSSLLSFPKTVSLENCFLIRHPDLGNKSYSLHSLFVVGSGHLTLTVAPLDKCRGHCEMFKVDLEAGDLGYASMDYWMMSFVAKGTEPAVVCYGAAS", "length": 393, "header": "tr|A0A8V1A659-1|A0A8V1A659_CHICK Isoform 1 of C6orf89 homolog OS=Gallus gallus OX=9031 GN=C6orf89 PE=4 SV=1 CANONICAL=A0A8V1A659-1" }, "locus": { "chromosome": "26", "start_pos": 1668722, "end_pos": 1652404, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010062572.1", "url": "https://www.ensembl.org/id/ENSGALT00010062572.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038684.1", "url": "https://www.ensembl.org/id/ENSGALP00010038684.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "Q6P6G2-1", "protein_name": "Bombesin receptor-activated protein C6orf89 homolog", "gene_name": "", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDLAANEISIYDKLSETVDLVRQTGHQCGMSEKAIEKFIRQLLEKNEPQRGPPQYPLLIAMYKVLLTLGLILFTAYFVIQPFSSLAPEPVLSGAHTWRSLIHHIRLVSLPITKKYMPENKGVPLQGREEDKPFPDFDPWSSNNCEQNESEPIPANCTVCAQILPLKVTLPEDTPKNFERLRPLVIKTGQPLLSAEIQSFSCQYPEVTEGFTEGVLTKWWRCFPERWFPFPYPWRRPLNRSQILRELFPVFTQLPFPKDASLNKCFLIQPEPVVGSKMHEVHDLFTIGSGEAMLQLIPPFQCRRHCQSVAMPIESGDIGYAGAAHWKVYIVARGVQPLVICDGTTLSEL", "length": 348 }, "evidence": [ { "id": "A0A8V1A659", "url": "https://omabrowser.org/oma/group/A0A8V1A659/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6UWU4-1", "protein_name": "Bombesin receptor-activated protein C6orf89", "gene_name": "C6orf89", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDLAANEISIYDKLSETVDLVRQTGHQCGMSEKAIEKFIRQLLEKNEPQRPPPQYPLLIVVYKVLATLGLILLTAYFVIQPFSPLAPEPVLSGAHTWRSLIHHIRLMSLPIAKKYMSENKGVPLHGGDEDRPFPDFDPWWTNDCEQNESEPIPANCTGCAQKHLKVMLLEDAPRKFERLHPLVIKTGKPLLEEEIQHFLCQYPEATEGFSEGFFAKWWRCFPERWFPFPYPWRRPLNRSQMLRELFPVFTHLPFPKDASLNKCSFLHPEPVVGSKMHKMPDLFIIGSGEAMLQLIPPFQCRRHCQSVAMPIEPGDIGYVDTTHWKVYVIARGVQPLVICDGTAFSEL", "length": 347 }, "evidence": [ { "id": "A0A8V1A659", "url": "https://omabrowser.org/oma/group/A0A8V1A659/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q99KU6-1", "protein_name": "Bombesin receptor-activated protein C6orf89 homolog", "gene_name": "", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDLAANEISIYDKLSETVDLVRQTGHQCGMSEKAIEKFIRQLLEKNEPQRGPPQYPLLIAVYKVLLTLGLILFTAYFVIQPFSSLAPEPVLSGANSWRSLVHHIRLVSLPITKKYMPENKGVPLQGSQEDKPFPDFDPWSSYNCEQNESEPIPANCTGCAQILPLKVTLPEDTPKNFERLRPLVIKTGQPLSSAEIQSFSCQYPEVTEGFTEGFFTKWWRCFPERWFPFPYPWRRPLNRSQILRELFPVFTQLPFPKDSSLNKCFLIQPEPVVGSKMHKVHDLFTLGSGEAMLQLIPPFQCRTHCQSVAMPIESGDIGYADAAHWKVYIVARGVQPLVICDGTTLSDL", "length": 348 }, "evidence": [ { "id": "A0A8V1A659", "url": "https://omabrowser.org/oma/group/A0A8V1A659/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A659", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A659" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 196, "end_pos": 198, "annotation": "n_glycosylation_sequon" }, { 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"Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052051", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052051", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR19433", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19433", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07686", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07686", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1A3Y8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3Y8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A3Y8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3Y8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "PHASLATCLQLVLNLLLVPFFPQKSAVTVQAGWTETLQCTYSSSASYIYVAWYRQLPKRSLQYLLQSKGRGGSYNHTAPFARLRFSSQADESSGTLVISGLQLEDSALYLCTLLGPQ", "length": 117, "header": "tr|A0A8V1A3Y8-1|A0A8V1A3Y8_CHICK Isoform 1 of Ig-like domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1A3Y8-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A3Y8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3Y8/entry#A0A8V1A3Y8-1", "sequence": { "sequence": "PHASLATCLQLVLNLLLVPFFPQKSAVTVQAGWTETLQCTYSSSASYIYVAWYRQLPKRSLQYLLQSKGRGGSYNHTAPFARLRFSSQADESSGTLVISGLQLEDSALYLCTLLGPQ", "length": 117, "header": "tr|A0A8V1A3Y8-1|A0A8V1A3Y8_CHICK Isoform 1 of Ig-like domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1A3Y8-1" }, "locus": { "chromosome": "27", "start_pos": 454639, "end_pos": 454137, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010062667.1", "url": "https://www.ensembl.org/id/ENSGALT00010062667.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038748.1", "url": "https://www.ensembl.org/id/ENSGALP00010038748.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A3Y8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3Y8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "immune system process", "id": "GO:0002376", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002376", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A3Y8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3Y8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 75, "end_pos": 77, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1A3Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3Y8" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 22, "end_pos": 117, "start_aa": "Pro", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 75, "end_pos": 77 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A3Y9-1", "uniprot_ac": "A0A8V1A3Y9", "uniprot_id": "A0A8V1A3Y9_CHICK", "mass": { "chemical_mass": 166920.0, "monoisotopic_mass": 166920.0 }, "refseq": {}, "gene_names": [ { "name": "FANCD2", "type": "recommended", "evidence": [ { "id": "A0A8V1A3Y9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3Y9" } ] } ], "protein_names": [ { "name": "Fanconi anemia complementation group D2", "type": "synonym", "evidence": [ { "id": "A0A8V1A3Y9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3Y9/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A3Y9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3Y9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FANCD2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3Y9", "locus": { "chromosome": "12", "start_pos": 2941992, "end_pos": 2989525, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027361", "url": "https://www.ensembl.org/id/ENSGALG00010027361" } ] } } ], "crossref": [ { "id": "cd11721", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11721", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR029448", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029448", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A3Y9", "url": "https://www.orthodb.org/?gene=A0A8V1A3Y9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A8U6", "url": "https://www.orthodb.org/?gene=A0A8V1A8U6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ABJ5", "url": "https://www.orthodb.org/?gene=A0A8V1ABJ5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AE92", "url": "https://www.orthodb.org/?gene=A0A8V1AE92", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AG99", "url": "https://www.orthodb.org/?gene=A0A8V1AG99", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR32086", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR32086", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR32086:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR32086:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14631", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14631", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-6783310", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6783310", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1A3Y9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3Y9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A3Y9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3Y9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A8U6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8U6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A8U6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8U6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ABJ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABJ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ABJ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABJ5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AE92", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE92", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AE92-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE92-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AG99", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG99", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AG99-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG99-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVSKRKLSKIDAAEESSKTDLQSRCPETKRSRISDKRAPSQGGLENEGVFEELLRTSGIILKVGEGQNEIAVDQTAFQKKLRVALEKHPSYPGVVNEFISGLESHIKDRSQFKNCLLPCTPARTEGSRTLVHSYCESLIKLLLGIKILQPAVVTLLLEKIPEFFFDVVGTFGTNFPRLIVNQFKWLDGLLDSQDLVKKLMQMLSVSPVPIQHDIITSLPEILEDSQQNEVARELSCLLKQGRRLTVPILDALSRLDLDAELLAEVRQSAMTIVPSVKLEDLPVVIKFILHNVKTADAVEVISDLRKSLDLSSCVLPLQLLGSQRKLKSQAQASSSMSQMTTSQNCVKLLFDVIKLAVRFQKDVSEAWIKAIENSTSVSDHKVLDLIVLLLIHSTNSKNRKQTEKVLRSKIRLGCMPEQLMQNAFQNHSMVIKDFFPSILSLAQTFLHSAHPAVVSFGSCMYKQAFAVFDSYCQQEVVCALVTHVCSGNETELDISLDVLTDLVILHPSLLLRYATFVKTILDSMQKLNPCQIRKLFYILSTLAFSQRQEGSYIQDDMHMVIRKWLSSSVPNHKQMGIIGAVTMMGSVALKRNEADGGLLERPELSIECDGQLSTLLDLVGFCCEQTPEVLALYYDELANLIEKQKGNLDLQLLDKFGKSLVEDFPNDFVVDLSPTVDGSFLFPVKSLYNLDEDETQGAIAINLLPLVSQSEPGRVADEMSNSRKRVVSPICLSPCFRLLRLYTGEQNNGSLEEIDALLGCPLYLTDLEVEGKLDSLSKQEREFLCSLLFYALNWFREVVNAFCQQQDAEMKGKVLTRLQNITELQNVLGKCLAATPGYVPPPATFDSEAPEGVPSINAGGPVRKKNGKKRKSDSSKACSAERTQADESSDGNQPDTELSELEKSAAEKETGNPLAQLQSYRPYFRELDLEVFSVLHCGLLTKSILDTEMHTEASEVVQLGPAELCFLLDDMCWKLEHVLTPGSTRRVPFLKERGNKDVGFSHLCQRSPKEVAVCVVKLLKPLCNHMENMHNYFQTVIPNQGVVDESGLNIQEYQLMSSCYHQLLLAFRLLFAWSGFSQHENSNLLRSALQVLADRLKPGETEFLPLEELISESFQYLLNFQASIPSFQCAFILTQVLMAISEKPMTGWKREKMASLAKQFLCQSWMKPGGDREKGSHFNSALHTLLCVYLEHTDNILKAIEEISSVGVPELINSAKDGCSSTYPTLSRQTFPVFFRVMMAQLESSVKSIPAGKPSDSGEVQLEKLLKWNIAVRNFHILINLVKVFDSRPVLSICLKYGRLFVEAFLKLAMPLLDHSFKKHRDDVQSLLKTLQLSTRQLHHMCGHSKIHQDLGLTNHVPLLKKSLEQFVYRVKAMLAFNHCQEAFWVGVLKNRDLQGEEILSQASAAPEEDSAEGSEEDTADSAAEIHQDWANREYIEVITSSIKKIADFLNSFDMSCRSRLATLNEKLTALERRIEYIEARVTKGETLT", "length": 1489, "header": "tr|A0A8V1A3Y9-1|A0A8V1A3Y9_CHICK Isoform 1 of Fanconi anemia complementation group D2 OS=Gallus gallus OX=9031 GN=FANCD2 PE=3 SV=1 CANONICAL=A0A8V1A3Y9-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A3Y9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3Y9/entry#A0A8V1A3Y9-1", "sequence": { "sequence": "MVSKRKLSKIDAAEESSKTDLQSRCPETKRSRISDKRAPSQGGLENEGVFEELLRTSGIILKVGEGQNEIAVDQTAFQKKLRVALEKHPSYPGVVNEFISGLESHIKDRSQFKNCLLPCTPARTEGSRTLVHSYCESLIKLLLGIKILQPAVVTLLLEKIPEFFFDVVGTFGTNFPRLIVNQFKWLDGLLDSQDLVKKLMQMLSVSPVPIQHDIITSLPEILEDSQQNEVARELSCLLKQGRRLTVPILDALSRLDLDAELLAEVRQSAMTIVPSVKLEDLPVVIKFILHNVKTADAVEVISDLRKSLDLSSCVLPLQLLGSQRKLKSQAQASSSMSQMTTSQNCVKLLFDVIKLAVRFQKDVSEAWIKAIENSTSVSDHKVLDLIVLLLIHSTNSKNRKQTEKVLRSKIRLGCMPEQLMQNAFQNHSMVIKDFFPSILSLAQTFLHSAHPAVVSFGSCMYKQAFAVFDSYCQQEVVCALVTHVCSGNETELDISLDVLTDLVILHPSLLLRYATFVKTILDSMQKLNPCQIRKLFYILSTLAFSQRQEGSYIQDDMHMVIRKWLSSSVPNHKQMGIIGAVTMMGSVALKRNEADGGLLERPELSIECDGQLSTLLDLVGFCCEQTPEVLALYYDELANLIEKQKGNLDLQLLDKFGKSLVEDFPNDFVVDLSPTVDGSFLFPVKSLYNLDEDETQGAIAINLLPLVSQSEPGRVADEMSNSRKRVVSPICLSPCFRLLRLYTGEQNNGSLEEIDALLGCPLYLTDLEVEGKLDSLSKQEREFLCSLLFYALNWFREVVNAFCQQQDAEMKGKVLTRLQNITELQNVLGKCLAATPGYVPPPATFDSEAPEGVPSINAGGPVRKKNGKKRKSDSSKACSAERTQADESSDGNQPDTELSELEKSAAEKETGNPLAQLQSYRPYFRELDLEVFSVLHCGLLTKSILDTEMHTEASEVVQLGPAELCFLLDDMCWKLEHVLTPGSTRRVPFLKERGNKDVGFSHLCQRSPKEVAVCVVKLLKPLCNHMENMHNYFQTVIPNQGVVDESGLNIQEYQLMSSCYHQLLLAFRLLFAWSGFSQHENSNLLRSALQVLADRLKPGETEFLPLEELISESFQYLLNFQASIPSFQCAFILTQVLMAISEKPMTGWKREKMASLAKQFLCQSWMKPGGDREKGSHFNSALHTLLCVYLEHTDNILKAIEEISSVGVPELINSAKDGCSSTYPTLSRQTFPVFFRVMMAQLESSVKSIPAGKPSDSGEVQLEKLLKWNIAVRNFHILINLVKVFDSRPVLSICLKYGRLFVEAFLKLAMPLLDHSFKKHRDDVQSLLKTLQLSTRQLHHMCGHSKIHQDLGLTNHVPLLKKSLEQFVYRVKAMLAFNHCQEAFWVGVLKNRDLQGEEILSQASAAPEEDSAEGSEEDTADSAAEIHQDWANREYIEVITSSIKKIADFLNSFDMSCRSRLATLNEKLTALERRIEYIEARVTKGETLT", "length": 1489, "header": "tr|A0A8V1A3Y9-1|A0A8V1A3Y9_CHICK Isoform 1 of Fanconi anemia complementation group D2 OS=Gallus gallus OX=9031 GN=FANCD2 PE=3 SV=1 CANONICAL=A0A8V1A3Y9-1" }, "locus": { "chromosome": "12", "start_pos": 2989032, "end_pos": 2942996, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066335.1", "url": "https://www.ensembl.org/id/ENSGALT00010066335.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040601.1", "url": "https://www.ensembl.org/id/ENSGALP00010040601.1" } ] } }, { "isoform_ac": "A0A8V1A8U6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3Y9/entry#A0A8V1A8U6-1", "sequence": { "sequence": "MVSKRKLSKIDAAEESSKTDLQSRCPETKRSRISDKRAPSQGGLENEGVFEELLRTSGIILKVGEGQNEIAVDQTAFQKKLRVALEKHPSYPGVVNEFISGLESHIKDRSQFKNCLLPCTPARTEGSRTLVHSYCESLIKLLLGIKILQPAVVTLLLEKIPEFFFDVVGTFGTNFPRLIVNQFKWLDGLLDSQDLVKKLMQMLSVSPVPIQHDIITSLPEILEDSQQNEVARELSCLLKQGRRLTVPILDALSRLDLDAELLAEVRQSAMTIVPSVKLEDLPVVIKFILHNVKTADAVEVISDLRKSLDLSSCVLPLQLLGSQRKLKSQAQASSSMSQMTTSQNCVKLLFDVIKLAVRFQKDVSEAWIKAIENSTSVSDHKVLDLIVLLLIHSTNSKNRKQTEKVLRSKIRLGCMPEQLMQNAFQNHSMVIKDFFPSILSLAQTFLHSAHPAVVSFGSCMYKQAFAVFDSYCQQEVVCALVTHVCSGNETELDISLDVLTDLVILHPSLLLRYATFVKDDMHMVIRKWLSSSVPNHKQMGIIGAVTMMGSVALKRNEADGGLLERPELSIECDGQLSTLLDLVGFCCEQTPEVLALYYDELANLIEKQKGNLDLQLLDKFGKSLVEDFPNDFVVDLSPTVDGSFLFPVKSLYNLDEDETQGAIAINLLPLVSQSEPGRVADEMSNSRKRVVSPICLSPCFRLLRLYTGEQNNGSLEEIDALLGCPLYLTDLEVEGKLDSLSKQEREFLCSLLFYALNWFREVVNAFCQQQDAEMKGKVLTRLQNITELQNVLGKCLAATPGYVPPPATFDSEAPEGVPSINAGGPVRKKNGKKRKSDSSKACSAERTQADESSDGNQPDTELSELEKSAAEKETGNPLAQLQSYRPYFRELDLEVFSVLHCGLLTKSILDTEMHTEASEVVQLGPAELCFLLDDMCWKLEHVLTPGSTRRVPFLKERGNKDVGFSHLCQRSPKEVAVCVVKLLKPLCNHMENMHNYFQTVIPNQGVVDESGLNIQEYQLMSSCYHQLLLAFRLLFAWSGFSQHENSNLLRSALQVLADRLKPGETEFLPLEELISESFQYLLNFQASIPSFQCAFILTQVLMAISEKPMTGWKREKMASLAKQFLCQSWMKPGGDREKGSHFNSALHTLLCVYLEHTDNILKAIEEISSVGVPELINSAKDGCSSTYPTLSRQTFPVFFRVMMAQLESSVKSIPAGKPSDSGEVQLEKLLKWNIAVRNFHILINLVKVFDSRPVLSICLKYGRLFVEAFLKLAMPLLDHSFKKHRDDVQSLLKTLQLSTRQLHHMCGHSKIHQDLGLTNHVPLLKKSLEQFVYRVKAMLAFNHCQEAFWVGVLKNRDLQGEEILSQASAAPEEDSAEGSEEDTADSAAEEPDGTDSDSGGAGR", "length": 1403, "header": "tr|A0A8V1A8U6-1|A0A8V1A8U6_CHICK Computationally mapped isoform of Fanconi anemia complementation group D2 OS=Gallus gallus OX=9031 GN=FANCD2 PE=3 SV=1 CANONICAL=A0A8V1A3Y9-1" }, "locus": { "chromosome": "12", "start_pos": 2989032, "end_pos": 2943466, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066332.1", "url": "https://www.ensembl.org/id/ENSGALT00010066332.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040598.1", "url": "https://www.ensembl.org/id/ENSGALP00010040598.1" } ] } }, { "isoform_ac": "A0A8V1ABJ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3Y9/entry#A0A8V1ABJ5-1", "sequence": { "sequence": "MVSKRKLSKIDAAEESSKTDLQSRCPETKRSRISDKRAPSQGGLENEGVFEELLRTSGIILKVGEGQNEIAVDQTAFQKKLRVALEKHPSYPGVVNEFISGLESHIKDRSQFKNCLLPCTPARTEGSRTLVHSYCESLIKLLLGIKILQPAVVTLLLEKIPEFFFDVVGTFGTNFPRLIVNQFKWLDGLLDSQDLVKKLMQMLSVSPVPIQHDIITSLPEILEDSQQNEVARELSCLLKQGRRLTVPILDALSRLDLDAELLAEVRQSAMTIVPSVKLEDLPVVIKFILHNVKTADAVEVISDLRKSLDLSSCVLPLQLLGSQRKLKSQAQASSSMSQMTTSQNCVKLLFDVIKLAVRFQKDVSEAWIKAIENSTSVSDHKVLDLIVLLLIHSTNSKNRKQTEKVLRSKIRLGCMPEQLMQNAFQNHSMVIKDFFPSILSLAQTFLHSAHPAVVSFGSCMYKQAFAVFDSYCQQEVVCALVTHVCSGNETELDISLDVLTDLVILHPSLLLRYATFVKTILDSMQKLNPCQIRKLFYILSTLAFSQRQEGSYIQDDMHMVIRKWLSSSVPNHKQMGIIGAVTMMGSVALKRNEADGGLLERPELSIECDGQLSTLLDLVGFCCEQTPEVLALYYDELANLIEKQKGNLDLQLLDKFGKSLVEDFPNDFVVDLSPTVDGSFLFPVKSLYNLDEDETQGAIAINLLPLVSQSEPGRVADEMSNSRKRVVSPICLSPCFRLLRLYTGEQNNGSLEEIDALLGCPLYLTDLEVEGKLDSLSKQEREFLCSLLFYALNWFREVVNAFCQQQDAEMKGKVLTRLQNITELQNVLGKCLAATPGYVPPPATFDSEAPEGVPSINAGGPVRKKNGKKRKSDSSKACSAERTQADESSDGNQPDTELSELEKSAAEKETGNPLAQLQSYRPYFRELDLEVFSVLHCGLLTKSILDTEMHTEASEVVQLGPAELCFLLDDMCWKLEHVLTPGSTRRVPFLKTVIPNQGVVDESGLNIQEYQLMSSCYHQLLLAFRLLFAWSGFSQHENSNLLRSALQVLADRLKPGETEFLPLEELISESFQYLLNFQASIPSFQCAFILTQVLMAISEKPMTGWKREKMASLAKQFLCQSWMKPGGDREKGSHFNSALHTLLCVYLEHTDNILKAIEEISSVGVPELINSAKDGCSSTYPTLSRQTFPVFFRVMMAQLESSVKSIPAGKPSDSGEVQLEKLLKWNIAVRNFHILINLVKVFDSRPVLSICLKYGRLFVEAFLKLAMPLLDHSFKKHRDDVQSLLKTLQLSTRQLHHMCGHSKIHQDLGLTNHVPLLKKSLEQFVYRVKAMLAFNHCQEAFWVGVLKNRDLQGEEILSQASAAPEEDSAEGSEEDTADSAAEEPDGTDSDSGGAGR", "length": 1396, "header": "tr|A0A8V1ABJ5-1|A0A8V1ABJ5_CHICK Computationally mapped isoform of Fanconi anemia complementation group D2 OS=Gallus gallus OX=9031 GN=FANCD2 PE=3 SV=1 CANONICAL=A0A8V1A3Y9-1" }, "locus": { "chromosome": "12", "start_pos": 2989032, "end_pos": 2943466, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066334.1", "url": "https://www.ensembl.org/id/ENSGALT00010066334.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040600.1", "url": "https://www.ensembl.org/id/ENSGALP00010040600.1" } ] } }, { "isoform_ac": "A0A8V1AE92-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3Y9/entry#A0A8V1AE92-1", "sequence": { "sequence": "MVSKRKLSKIDAAEESSKTDLQSRCPETKRSRISDKRAPSQGGLENEGVFEELLRTSGIILKVGEGQNEIAVDQTAFQKKLRVALEKHPSYPGVVNEFISGLESHIKDRSQFKNCLLPCTPARTEGSRTLVHSYCESLIKLLLGIKILQPAVVTLLLEKIPEFFFDVVGTFGTNFPRLIVNQFKWLDGLLDSQDLVKKLMQMLSVSPVPIQHDIITSLPEILEDSQQNEVARELSCLLKQGRRLTVPILDALSRLDLDAELLAEVISDLRKSLDLSSCVLPLQLLGSQRKLKSQAQASSSMSQMTTSQNCVKLLFDVIKLAVRFQKDVSEAWIKAIENSTSVSDHKVLDLIVLLLIHSTNSKNRKQTEKVLRSKIRLGCMPEQLMQNAFQNHSMVIKDFFPSILSLAQTFLHSAHPAVVSFGSCMYKQAFAVFDSYCQQEVVCALVTHVCSGNETELDISLDVLTDLVILHPSLLLRYATFVKTILDSMQKLNPCQIRKLFYILSTLAFSQRQEGSYIQDDMHMVIRKWLSSSVPNHKQMGIIGAVTMMGSVALKRNEADGGLLERPELSIECDGQLSTLLDLVGFCCEQTPEVLALYYDELANLIEKQKGNLDLQLLDKFGKSLVEDFPNDFVVDLSPTVDGSFLFPVKSLYNLDEDETQGAIAINLLPLVSQSEPGRVADEMSNSRKRVVSPICLSPCFRLLRLYTGEQNNGSLEEIDALLGCPLYLTDLEVEGKLDSLSKQEREFLCSLLFYALNWFREVVNAFCQQQDAEMKGKVLTRLQNITELQNVLGKCLAATPGYVPPPATFDSEAPEGVPSINAGGPVRKKNGKKRKSDSSKACSAERTQADESSDGNQPDTELSELEKSAAEKETGNPLAQLQSYRPYFRELDLEVFSVLHCGLLTKSILDTEMHTEASEVVQLGPAELCFLLDDMCWKLEHVLTPGSTRRVPFLKERGNKDVGFSHLCQRSPKEVAVCVVKLLKPLCNHMENMHNYFQTVIPNQGVVDESGLNIQEYQLMSSCYHQLLLAFRLLFAWSGFSQHENSNLLRSALQVLADRLKPGETEFLPLEELISESFQYLLNFQASIPSFQCAFILTQVLMAISEKPMTGWKREKMASLAKQFLCQSWMKPGGDREKGSHFNSALHTLLCVYLEHTDNILKAIEEISSVGVPELINSAKDGCSSTYPTLSRQTFPVFFRVMMAQLESSVKSIPAGKPSDSGEVQLEKLLKWNIAVRNFHILINLVKVFDSRPVLSICLKYGRLFVEAFLKLAMPLLDHSFKKHRDDVQSLLKTLQLSTRQLHHMCGHSKIHQDLGLTNHVPLLKKSLEQFVYRVKAMLAFNHCQEAFWVGVLKNRDLQGEEILSQASAAPEEDSAEGSEEDTADSAAEEPDGTDSDSGGAGR", "length": 1404, "header": "tr|A0A8V1AE92-1|A0A8V1AE92_CHICK Computationally mapped isoform of Fanconi anemia complementation group D2 OS=Gallus gallus OX=9031 GN=FANCD2 PE=3 SV=1 CANONICAL=A0A8V1A3Y9-1" }, "locus": { "chromosome": "12", "start_pos": 2989032, "end_pos": 2943466, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066333.1", "url": "https://www.ensembl.org/id/ENSGALT00010066333.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040599.1", "url": "https://www.ensembl.org/id/ENSGALP00010040599.1" } ] } }, { "isoform_ac": "A0A8V1AG99-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3Y9/entry#A0A8V1AG99-1", "sequence": { "sequence": "MVSKRKLSKIDAAEESSKTDLQSRCPETKRSRISDKRAPSQGGLENEGVFEELLRTSGIILKVGEGQNEIAVDQTAFQKKLRVALEKHPSYPGVVNEFISGLESHIKDRSQFKNCLLPCTPARTEGSRTLVHSYCESLIKLLLGIKILQPAVVTLLLEKIPEFFFDVVGTFGTNFPRLIVNQFKWLDGLLDSQDLVKKLMQMLSVSPVPIQHDIITSLPEILEDSQQNEVARELSCLLKQGRRLTVPILDALSRLDLDAELLAEVRQSAMTIVPSVKLEDLPVVIKFILHNVKTADAVEVISDLRKSLDLSSCVLPLQLLGSQRKLKSQAQASSSMSQMTTSQNCVKLLFDVIKLAVRFQKDVSEAWIKAIENSTSVSDHKVLDLIVLLLIHSTNSKNRKQTEKVLRSKIRLGCMPEQLMQNAFQNHSMVIKDFFPSILSLAQTFLHSAHPAVVSFGSCMYKQAFAVFDSYCQQEVVCALVTHVCSGNETELDISLDVLTDLVILHPSLLLRYATFVKTILDSMQKLNPCQIRKLFYILSTLAFSQRQEGSYIQDDMHMVIRKWLSSSVPNHKQMGIIGAVTMMGSVALKRNEADGGLLERPELSIECDGQLSTLLDLVGFCCEQTPEVLALYYDELANLIEKQKGNLDLQLLDKFGKSLVEDFPNDFVVDLSPTVDGSFLFPVKSLYNLDEDETQGAIAINLLPLVSQSEPGRVADEMSNSRKRVVSPICLSPCFRLLRLYTGEQNNGSLEEIDALLGCPLYLTDLEVEGKLDSLSKQEREFLCSLLFYALNWFREVVNAFCQQQDAEMKGKVLTRLQNITELQNVLGKCLAATPGYVPPPATFDSEAPEGVPSINAGGPVRKKNGKKRKSDSSKACSAERTQADESSDGNQPDTELSELEKSAAEKETGNPLAQLQSYRPYFRELDLEVFSVLHCGLLTKSILDTEMHTEERGNKDVGFSHLCQRSPKEVAVCVVKLLKPLCNHMENMHNYFQTVIPNQGVVDESGLNIQEYQLMSSCYHQLLLAFRLLFAWSGFSQHENSNLLRSALQVLADRLKPGETEFLPLEELISESFQYLLNFQASIPSFQCAFILTQVLMAISEKPMTGWKREKMASLAKQFLCQSWMKPGGDREKGSHFNSALHTLLCVYLEHTDNILKAIEEISSVGVPELINSAKDGCSSTYPTLSRQTFPVFFRVMMAQLESSVKSIPAGKPSDSGEVQLEKLLKWNIAVRNFHILINLVKVFDSRPVLSICLKYGRLFVEAFLKLAMPLLDHSFKKHRDDVQSLLKTLQLSTRQLHHMCGHSKIHQDLGLTNHVPLLKKSLEQFVYRVKAMLAFNHCQEAFWVGVLKNRDLQGEEILSQASAAPEEDSAEGSEEDTADSAAEEPDGTDSDSGGAGR", "length": 1400, "header": "tr|A0A8V1AG99-1|A0A8V1A3Y9_CHICK Computationally mapped isoform of Fanconi anemia complementation group D2 OS=Gallus gallus OX=9031 GN=FANCD2 PE=3 SV=1 CANONICAL=A0A8V1A3Y9-1" }, "locus": { "chromosome": "12", "start_pos": 2989032, "end_pos": 2943466, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066331.1", "url": "https://www.ensembl.org/id/ENSGALT00010066331.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040597.1", "url": "https://www.ensembl.org/id/ENSGALP00010040597.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 835, "start_aa": "Thr", "end_pos": 835, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr835", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-GGA-6783310", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6783310", "resource": "Reactome", "description": "Fanconi Anemia Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A3Y9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3Y9" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A3Y9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3Y9" } ], "pmid": "" }, { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A3Y9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3Y9" } ], "pmid": "" }, { "name": "nuclear body", "id": "GO:0016604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016604", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A3Y9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3Y9" } ], "pmid": "" }, { "name": "condensed chromosome", "id": "GO:0000793", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000793", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A3Y9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3Y9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "response to gamma radiation", "id": "GO:0010332", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010332", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A3Y9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3Y9" } ], "pmid": "" }, { "name": "mitotic intra-S DNA damage checkpoint signaling", "id": "GO:0031573", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031573", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A3Y9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3Y9" } ], "pmid": "" }, { "name": "interstrand cross-link repair", "id": "GO:0036297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036297", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A3Y9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3Y9" } ], "pmid": "" }, { "name": "homologous chromosome pairing at meiosis", "id": "GO:0007129", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007129", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A3Y9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3Y9" } ], "pmid": "" }, { "name": "double-strand break repair involved in meiotic recombination", "id": "GO:1990918", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990918", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A3Y9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3Y9" } ], "pmid": "" }, { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A3Y9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3Y9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "DNA polymerase binding", "id": "GO:0070182", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070182", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A3Y9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3Y9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 373, "end_pos": 375, "annotation": "n_glycosylation_sequon" }, { "start_pos": 426, "end_pos": 428, "annotation": "n_glycosylation_sequon" }, { "start_pos": 488, "end_pos": 490, "annotation": "n_glycosylation_sequon" }, { "start_pos": 748, "end_pos": 750, "annotation": "n_glycosylation_sequon" }, { "start_pos": 820, "end_pos": 822, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 835 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 373, "end_pos": 375 }, { "start_pos": 426, "end_pos": 428 }, { "start_pos": 488, "end_pos": 490 }, { "start_pos": 748, "end_pos": 750 }, { "start_pos": 820, "end_pos": 822 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A417-1", "uniprot_ac": "A0A8V1A417", "uniprot_id": "A0A8V1A417_CHICK", "mass": { "chemical_mass": 135284.0, "monoisotopic_mass": 135284.0 }, "refseq": {}, "gene_names": [ { "name": "PLEKHA6", "type": "recommended", "evidence": [ { "id": "A0A8V1A417", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A417" } ] } ], "protein_names": [ { "name": "Pleckstrin homology domain containing A6", "type": "synonym", "evidence": [ { "id": "A0A8V1A417", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A417/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A417", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A417" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PLEKHA6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A417", "locus": { "chromosome": "26", "start_pos": 1772404, "end_pos": 1815308, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027365", "url": "https://www.ensembl.org/id/ENSGALG00010027365" } ] } } ], "crossref": [ { "id": "A0A8V1A417", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A417", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00201", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00201", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd13248", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13248", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "419821", "url": "https://www.ncbi.nlm.nih.gov/gene/419821", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001202", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001202", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036020", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036020", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040392", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040392", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057971", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057971", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A407", "url": "https://www.orthodb.org/?gene=A0A8V1A407", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A417", "url": "https://www.orthodb.org/?gene=A0A8V1A417", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A8W0", "url": "https://www.orthodb.org/?gene=A0A8V1A8W0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ABK7", "url": "https://www.orthodb.org/?gene=A0A8V1ABK7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ABL2", "url": "https://www.orthodb.org/?gene=A0A8V1ABL2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ABM2", "url": "https://www.orthodb.org/?gene=A0A8V1ABM2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AEB4", "url": "https://www.orthodb.org/?gene=A0A8V1AEB4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AGC4", "url": "https://www.orthodb.org/?gene=A0A8V1AGC4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12752", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12752", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12752:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12752:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00169", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00169", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25541", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25541", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1A407", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A407", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A407-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A407-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A417", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A417", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A417-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A417-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A8W0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8W0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A8W0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8W0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ABK7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABK7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ABK7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABK7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ABL2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABL2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ABL2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABL2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ABM2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABM2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ABM2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABM2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AEB4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEB4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AEB4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEB4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGC4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGC4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGC4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGC4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MADDIDWLDLPGRWTYGVCGDGRIFFINDETKSTSWVHPGTGYSIQSGHFSCAGLPRGWEVDTTLHGGFYFINHNERRNTFLHPVTGQLPEENSRLDLQKPTLDMSSKAGSKRPANSSSSSEPSNHTMVTEVAPERPGGRVRARVHVAQRATTEQMGSGGQTRALSSSSPPLQASRSSRKGITFGKRSNSMKRNPNAAVTKSGWLYKQASSGVKQWNKRWFVLVDRCLFYYKDEKEESILGSIPLLSFRVAAVQPSDNISRKHTFKAEHAGIRTYFFSAENTEEQESWIQAMGEAARVQIPPTQRHEKTDSENIPPSKHHHHHRNTVHHEHPKADPDAKTRGEGDGRGSEKLERKPERIESKKEPLAKANGIAGQEIPSEPGSPYPEAPRAPTSTERPPQPNGWPYTSPSRPGSTAYPPPDGESAAHRRSFAPRTNPEKIAQRKSSMTQLQQWVNLRRGNVPPEELRSPTRFYPVSRRVPDYYPPYSPQYPEDYQYYPPGVRPDSICSMPAYERVSPPWALEDKRHSFRNGGPYQLREWKEHPSFGRQDVPVWLPGRQPTYFDEVDAASGSLRRMSLQPRSRSVPRSPSQGSYSHTRVYSPVRSPSARFERLPPHGEEIYVDPGTFMMRRSISSPKYDYLGDRRPIPAGMYPYHYPASPTVHDKMVTTPFPEAYRETLHAYKISEQDTDKLLGKLCEQNKVLREQERLVQQLRAEKESLESALMGTHQELEMFGSQPAYPEKLLHKKESLQNQLINIRVELSQASTALANSTAEYETLESEVSALHDDLWEQLNLDIQNEMLNRQIQKEIWRIQDVMEGLRKNNPSRGTDTAKHRVAIGPSGTYSSNSPASPLSSASLTSPLSPFSLISGSQGSPTKPGPSEPKPSLEQSKKETQRTAAPGPTAEGLQSRQEQEAEKQAALNKVGIVPPRTKSPTEEEVVPTTGMLRRSASGMANGLGSRERPKSAVFANETKVKMSVEEQIDRMKRHQSGSMKEKRRSLQLPGSQQPDTPGTKAPASYKVVRRHRSIHEVDISDLEAALRSDEPGKVHETPREEIARLRKMELEPQHYDVDINKELSTPDKVLIPERYIELEPDTPLSPEEMKEKQKKVERIKTLIAKSSLQNVIPLGEGEVDAPQDPETQLQEQEKRIEISCALAAEASRRGRMLSAQCATPSPPTSPASPTPPTNPLSSEPSRVADCSHFMRV", "length": 1206, "header": "tr|A0A8V1A417-1|A0A8V1A417_CHICK Isoform 1 of Pleckstrin homology domain containing A6 OS=Gallus gallus OX=9031 GN=PLEKHA6 PE=4 SV=1 CANONICAL=A0A8V1A417-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A407-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A417/entry#A0A8V1A407-1", "sequence": { "sequence": "MSSKAGSKRPANSSSSSEPSNHTMVTEVAPERPGGRVRARVHVAQRATTEQMGSGGQTRALSSSSPPLQASRSSRKGITFGKRSNSMKRNPNAAVTKSGWLYKQASSGVKQWNKRWFVLVDRCLFYYKDEKEESILGSIPLLSFRVAAVQPSDNISRKHTFKAEHAGIRTYFFSAENTEEQESWIQAMGEAARVQIPPTQRHEKTDSENIPPSKHHHHHRNTVHHEHPKADPDAKTRGEGDGRGSEKLERKPERIESKKEPLAKANGIAGQEIPSEPGSPYPEAPRAPTSTERPPQPNGWPYTSPSRPGSTAYPPPDGESAAHRRSFAPRTNPEKIAQRKSSMTQLQQWVNLRRGNVPPEELRSPTRFYPVSRRVPDYYPPYSPQYPEDYQYYPPGVRPDSICSMPAYERVSPPWALEDKRHSFRNGGPYQLREWKEHPSFGRQDVPVWLPGRQPTYFDEVDAASGSLRRMSLQPRSRSVPRSPSQGSYSHTRVYSPVRSPSARFERLPPHGEEIYVDPGTFMMRRSISSPKYDYLGDRRPIPAGMYPYHYPASPTVHDKMMSESETLISMVNRMVESSSPRAQLYMQVTTPFPEAYRETLHAYKISEQDTDKLLGKLCEQNKVLREQERLVQQLRAEKESLESALMGTHQELEMFGSQPAYPEKLLHKKESLQNQLINIRVELSQASTALANSTAEYETLESEVSALHDDLWEQLNLDIQNEMLNRQIQKEIWRIQDVMEGLRKNNPSRGTDTAKHRVAIGPSGTYSSNSPASPLSSASLTSPLSPFSLISGSQGSPTKPGPSEPKPSLEQSKKETQRTAAPGPTAEGLQSRQEQEAEKQAALNKVGIVPPRTKSPTEEEVVPTTGMLRRSASGMANGLGSRERPKSAVFANETKVKMSVEEQIDRMKRHQSGSMKEKRRSLQLPGSQQPDTPGTKAPASYKVVRRHRSIHEVDISDLEAALRSDEPGKVHETPREEIARLRKMELEPQHYDVDINKELSTPDKVLIPERYIELEPDTPLSPEEMKEKQKKVERIKTLIAKSSLQNVIPLGEGEVDAPQDPETQLQEQEKRIEISCALAAEASRRGRMLSAQALAAAGAIKFHGATF", "length": 1108, "header": "tr|A0A8V1A407-1|A0A8V1A417_CHICK Computationally mapped isoform of Pleckstrin homology domain containing A6 OS=Gallus gallus OX=9031 GN=PLEKHA6 PE=4 SV=1 CANONICAL=A0A8V1A417-1" }, "locus": { "chromosome": "26", "start_pos": 1788828, "end_pos": 1773408, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066350.1", "url": "https://www.ensembl.org/id/ENSGALT00010066350.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040616.1", "url": "https://www.ensembl.org/id/ENSGALP00010040616.1" } ] } }, { "isoform_ac": "A0A8V1A417-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A417/entry#A0A8V1A417-1", "sequence": { "sequence": "MADDIDWLDLPGRWTYGVCGDGRIFFINDETKSTSWVHPGTGYSIQSGHFSCAGLPRGWEVDTTLHGGFYFINHNERRNTFLHPVTGQLPEENSRLDLQKPTLDMSSKAGSKRPANSSSSSEPSNHTMVTEVAPERPGGRVRARVHVAQRATTEQMGSGGQTRALSSSSPPLQASRSSRKGITFGKRSNSMKRNPNAAVTKSGWLYKQASSGVKQWNKRWFVLVDRCLFYYKDEKEESILGSIPLLSFRVAAVQPSDNISRKHTFKAEHAGIRTYFFSAENTEEQESWIQAMGEAARVQIPPTQRHEKTDSENIPPSKHHHHHRNTVHHEHPKADPDAKTRGEGDGRGSEKLERKPERIESKKEPLAKANGIAGQEIPSEPGSPYPEAPRAPTSTERPPQPNGWPYTSPSRPGSTAYPPPDGESAAHRRSFAPRTNPEKIAQRKSSMTQLQQWVNLRRGNVPPEELRSPTRFYPVSRRVPDYYPPYSPQYPEDYQYYPPGVRPDSICSMPAYERVSPPWALEDKRHSFRNGGPYQLREWKEHPSFGRQDVPVWLPGRQPTYFDEVDAASGSLRRMSLQPRSRSVPRSPSQGSYSHTRVYSPVRSPSARFERLPPHGEEIYVDPGTFMMRRSISSPKYDYLGDRRPIPAGMYPYHYPASPTVHDKMVTTPFPEAYRETLHAYKISEQDTDKLLGKLCEQNKVLREQERLVQQLRAEKESLESALMGTHQELEMFGSQPAYPEKLLHKKESLQNQLINIRVELSQASTALANSTAEYETLESEVSALHDDLWEQLNLDIQNEMLNRQIQKEIWRIQDVMEGLRKNNPSRGTDTAKHRVAIGPSGTYSSNSPASPLSSASLTSPLSPFSLISGSQGSPTKPGPSEPKPSLEQSKKETQRTAAPGPTAEGLQSRQEQEAEKQAALNKVGIVPPRTKSPTEEEVVPTTGMLRRSASGMANGLGSRERPKSAVFANETKVKMSVEEQIDRMKRHQSGSMKEKRRSLQLPGSQQPDTPGTKAPASYKVVRRHRSIHEVDISDLEAALRSDEPGKVHETPREEIARLRKMELEPQHYDVDINKELSTPDKVLIPERYIELEPDTPLSPEEMKEKQKKVERIKTLIAKSSLQNVIPLGEGEVDAPQDPETQLQEQEKRIEISCALAAEASRRGRMLSAQCATPSPPTSPASPTPPTNPLSSEPSRVADCSHFMRV", "length": 1206, "header": "tr|A0A8V1A417-1|A0A8V1A417_CHICK Isoform 1 of Pleckstrin homology domain containing A6 OS=Gallus gallus OX=9031 GN=PLEKHA6 PE=4 SV=1 CANONICAL=A0A8V1A417-1" }, "locus": { "chromosome": "26", "start_pos": 1815109, "end_pos": 1773828, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066360.1", "url": "https://www.ensembl.org/id/ENSGALT00010066360.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040626.1", "url": "https://www.ensembl.org/id/ENSGALP00010040626.1" } ] } }, { "isoform_ac": "A0A8V1A8W0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A417/entry#A0A8V1A8W0-1", "sequence": { "sequence": "MSSKAGSKRPANSSSSSEPSNHTMVTEVAPERPGGRVRARVHVAQRATTEQMGSGGQTRALSSSSPPLQASRSSRKGITFGKRSNSMKRNPNAAVTKSGWLYKQASSGVKQWNKRWFVLVDRCLFYYKDEKEESILGSIPLLSFRVAAVQPSDNISRKHTFKAEHAGIRTYFFSAENTEEQESWIQAMGEAARVQIPPTQRHEKTDSENIPPSKHHHHHRNTVHHEHPKADPDAKTRGEGDGRGSEKLERKPERIESKKEPLAKANGIAGQEIPSEPGSPYPEAPRAPTSTERPPQPNGWPYTSPSRPGSTAYPPPDGESAAHRRSFAPRTNPEKIAQRKSSMTQLQQWVNLRRGNVPPEELRSPTRFYPVSRRVPDYYPPYSPQYPEDYQYYPPGVRPDSICSMPAYERVSPPWALEDKRHSFRNGGPYQLREWKEHPSFGRQDVPVWLPGRQPTYFDEVDAASGSLRRMSLQPRSRSVPRSPSQGSYSHTRVYSPVRSPSARFERLPPHGEEIYVDPGTFMMRRSISSPKYDYLGDRRPIPAGMYPYHYPASPTVHDKMVTTPFPEAYRETLHAYKISEQDTDKLLGKLCEQNKVLREQERLVQQLRAEKESLESALMGTHQELEMFGSQPAYPEKLLHKKESLQNQLINIRVELSQASTALANSTAEYETLESEVSALHDDLWEQLNLDIQNEMLNRQIQKEIWRIQDVMEGLRKNNPSRGTDTAKHRVAIGPSGTYSSNSPASPLSSASLTSPLSPFSLISGSQGSPTKPGPSEEPGPPRPPLPKSYIPLEPPPTVPPLPSESRPWPYPTSPSWQRGGESQRGQPKPSLEQSKKETQRTAAPGPTAEGLQSRQEQEAEKQAALNKVGIVPPRTKSPTEEEVVPTTGMLRRSASGMANGLGSRERPKSAVFANETKVKMSVEEQIDRMKRHQSGSMKEKRRSLQLPGSQQPDTPGTKAPASYKVVRRHRSIHEVDISDLEAALRSDEPGKVHETPREEIARLRKMELEPQHYDVDINKELSTPDKVLIPERYIELEPDTPLSPEEMKEKQKKVERIKTLIAKSSLQNVIPLGEGEVDAPQDPETQLQEQEKRIEISCALAAEASRRGRMLSAQCATPSPPTSPASPTPPTNPLSSEPSRVADCSHFMRV", "length": 1152, "header": "tr|A0A8V1A8W0-1|A0A8V1A8W0_CHICK Computationally mapped isoform of Pleckstrin homology domain containing A6 OS=Gallus gallus OX=9031 GN=PLEKHA6 PE=4 SV=1 CANONICAL=A0A8V1A417-1" }, "locus": { "chromosome": "26", "start_pos": 1788828, "end_pos": 1773828, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066347.1", "url": "https://www.ensembl.org/id/ENSGALT00010066347.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040613.1", "url": "https://www.ensembl.org/id/ENSGALP00010040613.1" } ] } }, { "isoform_ac": "A0A8V1ABK7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A417/entry#A0A8V1ABK7-1", "sequence": { "sequence": "MLKFRADRRVSHNERRNTFLHPVTGQLPEENSRLDLQKPTLDMSSKAGSKRPANSSSSSEPSNHTMVTEVAPERPGGRVRARVHVAQRATTEQMGSGGQTRALSSSSPPLQASRSSRKGITFGKRSNSMKRNPNAAVTKSGWLYKQASSGVKQWNKRWFVLVDRCLFYYKDEKEESILGSIPLLSFRVAAVQPSDNISRKHTFKVTVCWVEEVPASNEQSLSPQAEHAGIRTYFFSAENTEEQESWIQAMGEAARVQIPPTQRHEKTDSENIPPSKHHHHHRNTVHHEHPKADPDAKTRGEGDGRGSEKLERKPERIESKKEPLAKANGIAGQEIPSEPGSPYPEAPRAPTSTERPPQPNGWPYTSPSRPGSTAYPPPDGESAAHRRSFAPRTNPEKIAQRKSSMTQLQQWVNLRRGNVPPEELRSPTRFYPVSRRVPDYYPPYSPQYPEDYQYYPPGVRPDSICSMPAYERVSPPWALEDKRHSFRNGGPYQLREWKEHPSFGRQDVPVWLPGRQPTYFDEVDAASGSLRRMSLQPRSRSVPRSPSQGSYSHTRVYSPVRSPSARFERLPPHGEEIYVDPGTFMMRRSISSPKYDYLGDRRPIPAGMYPYHYPASPTVHDKMVTTPFPEAYRETLHAYKISEQDTDKLLGKLCEQNKVLREQERLVQQLRAEKESLESALMGTHQELEMFGSQPAYPEKLLHKKESLQNQLINIRVELSQASTALANSTAEYETLESEVSALHDDLWEQLNLDIQNEMLNRQIQKEIWRIQDVMEGLRKNNPSRGTDTAKHRVAIGPSGTYSSNSPASPLSSASLTSPLSPFSLISGSQGSPTKPGPSEPKPSLEQSKKETQRTAAPGPTAEGLQSRQEQEAEKQAALNKVGIVPPRTKSPTEEEVVPTTGMLRRSASGMANGLGSRERPKSAVFANETKVKMSVEEQIDRMKRHQSGSMKEKRRSLQLPGSQQPDTPGTKAPASYKVVRRHRSIHEVDISDLEAALRSDEPGKVHETPREEIARLRKMELEPQHYDVDINKELSTPDKVLIPERYIELEPDTPLSPEEMKEKQKKVERIKTLIAKSSLQNVIPLGEGEVDAPQDPETQLQEQEKRIEISCALAAEASRRGRMLSAQALAAAGAIKFHGATF", "length": 1143, "header": "tr|A0A8V1ABK7-1|A0A8V1ABK7_CHICK Computationally mapped isoform of Pleckstrin homology domain containing A6 OS=Gallus gallus OX=9031 GN=PLEKHA6 PE=4 SV=1 CANONICAL=A0A8V1A417-1" }, "locus": { "chromosome": "26", "start_pos": 1790714, "end_pos": 1773408, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066344.1", "url": "https://www.ensembl.org/id/ENSGALT00010066344.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040610.1", "url": "https://www.ensembl.org/id/ENSGALP00010040610.1" } ] } }, { "isoform_ac": "A0A8V1ABL2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A417/entry#A0A8V1ABL2-1", "sequence": { "sequence": 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"length": 1125, "header": "tr|A0A8V1ABL2-1|A0A8V1ABL2_CHICK Computationally mapped isoform of Pleckstrin homology domain containing A6 OS=Gallus gallus OX=9031 GN=PLEKHA6 PE=4 SV=1 CANONICAL=A0A8V1A417-1" }, "locus": { "chromosome": "26", "start_pos": 1788828, "end_pos": 1773408, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066349.1", "url": "https://www.ensembl.org/id/ENSGALT00010066349.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040615.1", "url": "https://www.ensembl.org/id/ENSGALP00010040615.1" } ] } }, { "isoform_ac": "A0A8V1ABM2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A417/entry#A0A8V1ABM2-1", "sequence": { "sequence": 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"length": 1131, "header": "tr|A0A8V1ABM2-1|A0A8V1ABM2_CHICK Computationally mapped isoform of Pleckstrin homology domain containing A6 OS=Gallus gallus OX=9031 GN=PLEKHA6 PE=4 SV=1 CANONICAL=A0A8V1A417-1" }, "locus": { "chromosome": "26", "start_pos": 1788828, "end_pos": 1773408, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066359.1", "url": "https://www.ensembl.org/id/ENSGALT00010066359.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040625.1", "url": "https://www.ensembl.org/id/ENSGALP00010040625.1" } ] } }, { "isoform_ac": "A0A8V1AEB4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A417/entry#A0A8V1AEB4-1", "sequence": { "sequence": "MLIHNERRNTFLHPVTGQLPEENSRLDLQKPTLDMSSKAGSKRPANSSSSSEPSNHTMVTEVAPERPGGRVRARVHVAQRATTEQMGSGGQTRALSSSSPPLQASRSSRKGITFGKRSNSMKRNPNAAVTKSGWLYKQASSGVKQWNKRWFVLVDRCLFYYKDEKEESILGSIPLLSFRVAAVQPSDNISRKHTFKAEHAGIRTYFFSAENTEEQESWIQAMGEAARVQIPPTQRHEKTDSENIPPSKHHHHHRNTVHHEHPKADPDAKTRGEGDGRGSEKLERKPERIESKKEPLAKANGIAGQEIPSEPGSPYPEAPRAPTSTERPPQPNGWPYTSPSRPGSTAYPPPDGESAAHRRSFAPRTNPEKIAQRKSSMTQLQQWVNLRRGNVPPEELRSPTRFYPVSRRVPDYYPPYSPQYPEDYQYYPPGVRPDSICSMPAYERVSPPWALEDKRHSFRNGGPYQLREWKEHPSFGRQDVPVWLPGRQPTYFDEVDAASGSLRRMSLQPRSRSVPRSPSQGSYSHTRVYSPVRSPSARFERLPPHGEEIYVDPGTFMMRRSISSPKYDYLGDRRPIPAGMYPYHYPASPTVHDKMVTTPFPEAYRETLHAYKISEQDTDKLLGKLCEQNKVLREQERLVQQLRAEKESLESALMGTHQELEMFGSQPAYPEKLLHKKESLQNQLINIRVELSQASTALANSTAEYETLESEVSALHDDLWEQLNLDIQNEMLNRQIQKEIWRIQDVMEGLRKNNPSRGTDTAKHRVAIGPSGTYSSNSPASPLSSASLTSPLSPFSLISGSQGSPTKPGPSEPKPSLEQSKKETQRTAAPGPTAEGLQSRQEQEAEKQAALNKVGIVPPRTKSPTEEEVVPTTGMLRRSASGMANGLGSRERPKSAVFANETKVKMSVEEQIDRMKRHQSGSMKEKRRSLQLPGSQQPDTPGTKAPASYKVVRRHRSIHEVDISDLEAALRSDEPGKVHETPREEIARLRKMELEPQHYDVDINKELSTPDKVLIPERYIELEPDTPLSPEEMKEKQKKVERIKTLIAKSSLQNVIPLGEGEVDAPQDPETQLQEQEKRIEISCALAAEASRRGRMLSAQCATPSPPTSPASPTPPTNPLSSEPSRVADCSHFMRV", "length": 1136, "header": "tr|A0A8V1AEB4-1|A0A8V1AEB4_CHICK Computationally mapped isoform of Pleckstrin homology domain containing A6 OS=Gallus gallus OX=9031 GN=PLEKHA6 PE=4 SV=1 CANONICAL=A0A8V1A417-1" }, "locus": { "chromosome": "26", "start_pos": 1809796, "end_pos": 1773828, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066353.1", "url": "https://www.ensembl.org/id/ENSGALT00010066353.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040619.1", "url": "https://www.ensembl.org/id/ENSGALP00010040619.1" } ] } }, { "isoform_ac": "A0A8V1AGC4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A417/entry#A0A8V1AGC4-1", "sequence": { "sequence": "MSSKAGSKRPANSSSSSEPSNHTMVTEVAPERPGGRVRARVHVAQRATTEQMGSGGQTRALSSSSPPLQASRSSRKGITFGKRSNSMKRNPNAAVTKSGWLYKQASSGVKQWNKRWFVLVDRCLFYYKDEKEESILGSIPLLSFRVAAVQPSDNISRKHTFKAEHAGIRTYFFSAENTEEQESWIQAMGEAARVQIPPTQRHEKTDSENIPPSKHHHHHRNTVHHEHPKADPDAKTRGEGDGRGSEKLERKPERIESKKEPLAKANGIAGQEIPSEPGSPYPEAPRAPTSTERPPQPNGWPYTSPSRPGSTAYPPPDGESAAHRRSFAPRTNPEKIAQRKSSMTQLQQWVNLRRGNVPPEELRSPTRFYPVSRRVPDYYPPYSPQYPEDYQYYPPGVRPDSICSMPAYERVSPPWALEDKRHSFRNGGPYQLREWKEHPSFGRQDVPVWLPGRQPTYFDEVDAASGSLRRMSLQPRSRSVPRSPSQGSYSHTRVYSPVRSPSARFERLPPHGEEIYVDPGTFMMRRSISSPKYDYLGDRRPIPAGMYPYHYPASPTVHDKMDELLDLQLQRNLEYLDQQMSESETLISMVNRMVESSSPRAQLYMQVTTPFPEAYRETLHAYKISEQDTDKLLGKLCEQNKVLREQERLVQQLRAEKESLESALMGTHQELEMFGSQPAYPEKLLHKKESLQNQLINIRVELSQASTALANSTAEYETLESEVSALHDDLWEQLNLDIQNEMLNRQIQKEIWRIQDVMEGLRKNNPSRGTDTAKHRVAIGPSGTYSSNSPASPLSSASLTSPLSPFSLISGSQGSPTKPGPSEEPGPPRPPLPKSYIPLEPPPTVPPLPSESRPWPYPTSPSWQRGGESQRGQPKPSLEQSKKETQRTAAPGPTAEGLQSRQEQEAEKQAALNKVGIVPPRTKSPTEEEVVPTTGMLRRSASGMANGLGSRERPKSAVFANETKVKMSVEEQIDRMKRHQSGSMKEKRRSLQLPGSQQPDTPGTKAPASYKVVRRHRSIHEVDISDLEAALRSDEPGKVHETPREEIARLRKMELEPQHYDVDINKELSTPDKVLIPERYIELEPDTPLSPEEMKEKQKKVERIKTLIAKSSLQNVIPLGEGEVDAPQDPETQLQEQEKRIEISCALAAEASRRGRMLSAQCATPSPPTSPASPTPPTNPLSSEPSRVADCSHFMRV", "length": 1197, "header": "tr|A0A8V1AGC4-1|A0A8V1A417_CHICK Computationally mapped isoform of Pleckstrin homology domain containing A6 OS=Gallus gallus OX=9031 GN=PLEKHA6 PE=4 SV=1 CANONICAL=A0A8V1A417-1" }, "locus": { "chromosome": "26", "start_pos": 1788828, "end_pos": 1773828, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066356.1", "url": "https://www.ensembl.org/id/ENSGALT00010066356.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040622.1", "url": "https://www.ensembl.org/id/ENSGALP00010040622.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1173, "start_aa": "Thr", "end_pos": 1173, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1173", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1184, "start_aa": "Thr", "end_pos": 1184, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1184", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 903, "start_aa": "Thr", "end_pos": 903, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr903", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 116, "end_pos": 118, "annotation": "n_glycosylation_sequon" }, { "start_pos": 125, "end_pos": 127, "annotation": "n_glycosylation_sequon" }, { "start_pos": 258, "end_pos": 260, "annotation": "n_glycosylation_sequon" }, { "start_pos": 770, "end_pos": 772, "annotation": "n_glycosylation_sequon" }, { "start_pos": 970, "end_pos": 972, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1A417", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A417" }, { "id": "PS50003", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50003" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PH", "eco_id": "ECO_0000259", "start_pos": 198, "end_pos": 297, "start_aa": "Ala", "end_aa": "Arg", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1A417", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A417" }, { "id": "PS50020", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50020" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "WW", "eco_id": "ECO_0000259", "start_pos": 8, "end_pos": 41, "start_aa": "Leu", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 903, 1173, 1184 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 116, "end_pos": 118 }, { "start_pos": 125, "end_pos": 127 }, { "start_pos": 258, "end_pos": 260 }, { "start_pos": 770, "end_pos": 772 }, { "start_pos": 970, "end_pos": 972 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 3 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 3 }, { "field": "exact_o_linked_sites", "count": 3 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 3 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 3 }, { "field": "exact_o_linked_sites", "count": 3 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A410-1", "uniprot_ac": "A0A8V1A410", "uniprot_id": "A0A8V1A410_CHICK", "mass": { "chemical_mass": 23166.0, "monoisotopic_mass": 23166.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Death domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8V1A410", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A410/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A410", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A410" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A410", "locus": {} } ], "crossref": [ { "id": "A0A8V1A410", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A410", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd08311", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08311", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000488", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000488", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011029", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011029", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041448", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041448", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052302", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052302", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR46605", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46605", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46605:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46605:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00531", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00531", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18422", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18422", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1A410", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A410", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A410-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A410-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A6D8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6D8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A6D8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6D8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "DGMGRVKGMGWAELRGWDGREGSTGPTASATSASTFVPPLPEDVGQNIIPVYCSLLAAVVVGLLAYVAFKCWHTCRQKQQLAKARAAELGTTAEGEKLHSDSGVFLDTHSLQEPHQMGKATRLEARPYSSVPQQRREEVEQLLESGGPSGDWRGLAARLGYGDEAVGTFARGQAPARTLLATWAATEGATVEALCRALAAMGRQDVAECLAGPGDASSVV", "length": 220, "header": "tr|A0A8V1A410-1|A0A8V1A410_CHICK Isoform 1 of Death domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1A410-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A410-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A410/entry#A0A8V1A410-1", "sequence": { "sequence": "DGMGRVKGMGWAELRGWDGREGSTGPTASATSASTFVPPLPEDVGQNIIPVYCSLLAAVVVGLLAYVAFKCWHTCRQKQQLAKARAAELGTTAEGEKLHSDSGVFLDTHSLQEPHQMGKATRLEARPYSSVPQQRREEVEQLLESGGPSGDWRGLAARLGYGDEAVGTFARGQAPARTLLATWAATEGATVEALCRALAAMGRQDVAECLAGPGDASSVV", "length": 220, "header": "tr|A0A8V1A410-1|A0A8V1A410_CHICK Isoform 1 of Death domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1A410-1" }, "locus": { "chromosome": "2", "start_pos": 3905518, "end_pos": 3903053, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010062728.1", "url": "https://www.ensembl.org/id/ENSGALT00010062728.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038773.1", "url": "https://www.ensembl.org/id/ENSGALP00010038773.1" } ] } }, { "isoform_ac": "A0A8V1A6D8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A410/entry#A0A8V1A6D8-1", "sequence": { "sequence": "TFPPPHHRQLLPHGCHHAPRAADEGSTGPTASATSASTFVPPLPEDVGQNIIPVYCSLLAAVVVGLLAYVAFKCWHTCRQKQQLAKARAAELGTTAEGEKLHSDSGVFLDTHSLQEPHQMGKGEQHPDRQRREEVEQLLESGGPSGDWRGLAARLGYGDEAVGTFARGQAPARTLLATWAATEGATVEALCRALAAMGRQDVAECLAGPGDASSVV", "length": 216, "header": "tr|A0A8V1A6D8-1|A0A8V1A6D8_CHICK Computationally mapped isoform of Death domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1A410-1" }, "locus": { "chromosome": "2", "start_pos": 3905518, "end_pos": 3903577, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010062718.1", "url": "https://www.ensembl.org/id/ENSGALT00010062718.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038770.1", "url": "https://www.ensembl.org/id/ENSGALP00010038770.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 27, "start_aa": "Thr", "end_pos": 27, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr27", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A410", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A410" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A410", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A410" } ], "pmid": "" }, { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A410", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A410" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1A410", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A410" }, { "id": "PS50017", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50017" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Death", "eco_id": "ECO_0000259", "start_pos": 151, "end_pos": 214, "start_aa": "Asp", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 27 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A425-1", "uniprot_ac": "A0A8V1A425", "uniprot_id": "A0A8V1A425_CHICK", "mass": { "chemical_mass": 48017.0, "monoisotopic_mass": 48017.0 }, "refseq": { "ac": "XP_015144985", "name": "BTB/POZ domain-containing protein KCTD18 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015144985" }, "gene_names": [ { "name": "KCTD18", "type": "recommended", "evidence": [ { "id": "A0A8V1A425", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A425" } ] }, { "name": "KCTD18", "type": "synonym", "evidence": [ { "id": "XP_015144985", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015144985" } ] } ], "protein_names": [ { "name": "BTB/POZ domain-containing protein KCTD18 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015144985", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015144985" } ] }, { "name": "Potassium channel tetramerization domain containing 18", "type": "synonym", "evidence": [ { "id": "A0A8V1A425", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A425/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052538.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015144985.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015144985", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015144985" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A425", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A425" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "KCTD18", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A425", "locus": { "chromosome": "7", "start_pos": 10790144, "end_pos": 10813158, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010024207", "url": "https://www.ensembl.org/id/ENSGALG00010024207" } ] } } ], "crossref": [ { "id": "A0A8V1A425", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A425", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd18372", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18372", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "424069", "url": "https://www.ncbi.nlm.nih.gov/gene/424069", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003131", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003131", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045704", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045704", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:424069", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424069", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CKAGPKP", "url": "https://omabrowser.org/oma/group/CKAGPKP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZRE3", "url": "https://www.orthodb.org/?gene=A0A8V0ZRE3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A425", "url": "https://www.orthodb.org/?gene=A0A8V1A425", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14499", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14499", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14499:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14499:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02214", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02214", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19321", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19321", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015144985", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015144985", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRE3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRE3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRE3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRE3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A425", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A425", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A425-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A425-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEEDKAAEEQGILRLNVRGCLYTARRQSLCRFKDSMLASMFSGRFPLKMDESGACLIDRDGSLFKYLLDYLHGEVRIPEDKQIRIALQEEADYFGIPYPYSLSDHLANEMETYSLRSNVELKKALLDFCDSYDLVCTKPTVWVLHYLSTSGASCESKIIGVYATRADGTDAINKELGTKIHSKSIYKREAGNNVQYIWSYYSEAELKKMMDAFGTWEGRGVSYWRVPQELIECWTLEERSLKGSLHHMPPVHKRRLIDFSEVEDYIPCKVGPKPIRFSGPSTSTHIKVKNSASLKVAACNTSHSAVTLKRPNSESLILHKAASKTVSTACVPEPSNSQVPHGKQSADDKASCQMTFNISVSRKPVSSRAVKLKRTPLFLVTPSQSSSVSSKTSEQDKAAAEIPTTSMVLNKKEPAMLAESIKLKSNKVDG", "length": 430, "header": "tr|A0A8V1A425-1|A0A8V1A425_CHICK Isoform 1 of Potassium channel tetramerization domain containing 18 OS=Gallus gallus OX=9031 GN=KCTD18 PE=4 SV=1 CANONICAL=A0A8V1A425-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZRE3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A425/entry#A0A8V0ZRE3-1", "sequence": { "sequence": "MEEDKAAEEQGILRLNVRGCLYTARRQSLCRFKDSMLASMFSGRFPLKMDESACLIDRDGSLFKYLLDYLHGEVRIPEDKQIRIALQEEADYFGIPYPYSLSDHLANEMETYSLRSNVELKKALLDFCDSYDLVCTKPTVWVLHYLSTSGASCESKIIGVYATRADGTDAINKELGTKIHSKSIYKREAGNNVQYIWSYYSEAELKKMMDAFGTWEGRGVSYWRVPQELIECWTLEERSLKGSLHHMPPVHKRRLIDFSEVEDYIPCKVGPKPIRFSGPSTSTHIKVKNSASLKVAACNTSHSAVTLKRPNSESLILHKAASKTVSTACVPEPSNSQVPHGKQSADDKASCQMTFNISVSRKPVSSRAVKLKRTPLFLVTPSQSSSVSSKTSEQDKAAAEIPTTSMVLNKKEPAMLAESIKLKSNKVDG", "length": 429, "header": "tr|A0A8V0ZRE3-1|A0A8V0ZRE3_CHICK Computationally mapped isoform of Potassium channel tetramerization domain containing 18 OS=Gallus gallus OX=9031 GN=KCTD18 PE=4 SV=1 CANONICAL=A0A8V1A425-1" }, "locus": { "chromosome": "7", "start_pos": 10797567, "end_pos": 10791580, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010059066.1", "url": "https://www.ensembl.org/id/ENSGALT00010059066.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036030.1", "url": "https://www.ensembl.org/id/ENSGALP00010036030.1" } ] } }, { "isoform_ac": "A0A8V1A425-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A425/entry#A0A8V1A425-1", "sequence": { "sequence": "MEEDKAAEEQGILRLNVRGCLYTARRQSLCRFKDSMLASMFSGRFPLKMDESGACLIDRDGSLFKYLLDYLHGEVRIPEDKQIRIALQEEADYFGIPYPYSLSDHLANEMETYSLRSNVELKKALLDFCDSYDLVCTKPTVWVLHYLSTSGASCESKIIGVYATRADGTDAINKELGTKIHSKSIYKREAGNNVQYIWSYYSEAELKKMMDAFGTWEGRGVSYWRVPQELIECWTLEERSLKGSLHHMPPVHKRRLIDFSEVEDYIPCKVGPKPIRFSGPSTSTHIKVKNSASLKVAACNTSHSAVTLKRPNSESLILHKAASKTVSTACVPEPSNSQVPHGKQSADDKASCQMTFNISVSRKPVSSRAVKLKRTPLFLVTPSQSSSVSSKTSEQDKAAAEIPTTSMVLNKKEPAMLAESIKLKSNKVDG", "length": 430, "header": "tr|A0A8V1A425-1|A0A8V1A425_CHICK Isoform 1 of Potassium channel tetramerization domain containing 18 OS=Gallus gallus OX=9031 GN=KCTD18 PE=4 SV=1 CANONICAL=A0A8V1A425-1" }, "locus": { "chromosome": "7", "start_pos": 10797567, "end_pos": 10791580, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010059067.1", "url": "https://www.ensembl.org/id/ENSGALT00010059067.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036031.1", "url": "https://www.ensembl.org/id/ENSGALP00010036031.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:424069", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424069", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A9J7FB93-1", "protein_name": "BTB/POZ domain-containing protein KCTD18", "gene_name": "Kctd18", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MPKLQESKGRMADHRAEDLLDILRLNVGGCIYTARRESLCRFKDSMLASMFSGRFPLKTDESGACIIDRDGQLFKYILDYLHGEVQIPSDEQTRTALQEEADYFGIPYPYSLSDHLANEMETYSLRSNIELKKALTDFCDSYGLICNKPTVWVLHYLNTSGASCESRIIGVYATKADGTDAIDKQLGGRIHSKSIFKREAGNNVQYIWSYYSVAELKKMMDAFDAWEGKGVSYWRVPHELIECWTLEERPLHGSLRHMTPIRKRRLLTLSEEDEGVNCKAGPKPVRFLGPSTSTQIKVKNSAAVRVSPVSAAQITSQATANRSQRGSYGKAAQCPVATGASGHAPASPQAQSAENQATQPPPAKVLLSDKKSPSNRVIKLRRTPLCVGTSLPTPSAGSQAGSPQQPSPEASITSGVRTETREDQPDG", "length": 427 }, "evidence": [ { "id": "A0A8V1A425", "url": "https://omabrowser.org/oma/group/A0A8V1A425/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "D4A827-1", "protein_name": "Potassium channel tetramerization domain containing 18", "gene_name": "Kctd18", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGHEAEEMRDILRLNVGGCIYTARRESLCRFKDSMLASMFSGRFPLKTDESGACIIDRDGHLFKYILDYLHGEVQTPSDEQTRTALQEEADYFGIPYPYSLSDHLANEMETYSLRSNIELKKALTDFCDSYGLVCNKPTVWVLHYLNTSGASCESRIIGVYSTKTDGTDAIDKQLGGRIHSKSIFKREAGNNVQYIWSYYSVAELKKMMDAFDAWEGKGVSYWRVPHELIECWTLEERPLHGSLRHMAPIRKRRLIAFGEEDEGVNCKTGPKPVRFLGPSTSTQIKVKNSASVRVSPANAAQISSQATANRSQRGSCGKAAQCSVATGASGHAPASPNAQSAENQATQPPPAKVLLSDKKSPPHRVIKLRRTPLCVGPSLPTPSAGSQASFPQQPSPEASNTLGVQTENRKDQPDG", "length": 417 }, "evidence": [ { "id": "A0A8V1A425", "url": "https://omabrowser.org/oma/group/A0A8V1A425/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E0CZ26-1", "protein_name": "Potassium channel tetramerisation domain containing 18", "gene_name": "Kctd18", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLKAELQASKGAMAGHEAEDVLDILRLNVGGCIYTARRESLCRFKDSMLASMFSGRFPLKTDESGACIINRDGHLFKYILDYLHGEVQTPSDEQTRAALQEEADYFGIPYPYSLSDHLANEMETYSLRSNIELKKALTDFCDSYGLVCNKPTVWVLHYLNTSGASCESRIIGVYATKTDGTDAIDKQLGGRIHSKSIFKREAGNNVQYIWSYYSVAELKKMMDAFDAWEGKGVSYWRVPHELIECWTLEERPLHGSLRHMAPIRKRRLIALREEDEGVNCKTGPKPVRFLGPSTSTQIKVKNSASVRVSPANAAQISSQATANRSHRGSCGKAAQCSVATGASGHAPASPDAQSSENQATHPPPAKVLLSEKKSPPPRVIKLRRTPLRGGPSLPTASAGGQACFPQPPSLEASSSLGVQMETRKDQPDG", "length": 429 }, "evidence": [ { "id": "A0A8V1A425", "url": "https://omabrowser.org/oma/group/A0A8V1A425/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F1SI68-1", "protein_name": "Potassium channel tetramerization domain containing 18", "gene_name": "KCTD18", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MESHKAEEEVVDILRLNVGGCIYTARRESLCRFKDSMLASMFSGRFPLKTDESGACVIDRDGHLFKYLLDYLHGEVHIPTEEQTRIALQEEADYFGIPYPYSLSDHLANEMETYSLRSNIELKKALTDFCDSYGLVCNKPTVWVLHYLNTSGASCESRIIGVYSTKTDGTDAIDKQLGGRIHSKSIFKREAGNNVQYIWSYYSVAELKKMMDAFDAWEGKGVSYWRVPHELIECWTLEERPLLGSLHHMAPIRKRRLTAFNEEEEEGENCKTGPKPVRFLGPSTSTQIKVKNSASVRVSPARASVNTAAGGKAAQRCAPTRVPSLVGTAGAENGAGHPPPAKVLLSDKKATPPRVIKLKRTPLCATGPSPPACPAARTVGTPEPPPNAPGALDLWTENGQRQTD", "length": 404 }, "evidence": [ { "id": "A0A8V1A425", "url": "https://omabrowser.org/oma/group/A0A8V1A425/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q29RJ0-1", "protein_name": "BTB/POZ domain-containing protein KCTD18", "gene_name": "KCTD18", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MEGHKAEEEVLDILRLNVGGCIYTARRESLCRFKDSMLASMFSGRFPLKTDESGACVIDRDGHLFKYLLDYLHGEVHIPTEEQTRVALQEEADYFGIPYPYSLSDHLANEMETYSLRSNIELKKALTDFCDSYGLVCNKPTVWVLHYLNTSGASCESRIIGVYSTKTDGTDAIDKQLGGRIHSKSIFKREAGNNVQYIWSDYSVAELKKMMDAFDAWEGKGVSYWRVPHELIECWTLEERPLLGSLSHMAPIRKRRLIVNEEEEEGVNCKTGPKPVRFLGPSTSTQIKVKNSASIRVSPASAPQPWPRATANLAAGGRAVQRSAQSKVPTPVGTGLPEHPQAAQGPGAPENGATHLPPAKVLLSDKTATPHRVIKLRRTPLCATGSSLPACTTPRPAGPPEPPPDALSPLGTWTENGQDQTK", "length": 422 }, "evidence": [ { "id": "A0A8V1A425", "url": "https://omabrowser.org/oma/group/A0A8V1A425/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q6PI47-1", "protein_name": "BTB/POZ domain-containing protein KCTD18", "gene_name": "KCTD18", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEGHKAEEEVLDVLRLNVGGCIYTARRESLCRFKDSMLASMFSGRFPLKTDESGACVIDRDGRLFKYLLDYLHGEVQIPTDEQTRIALQEEADYFGIPYPYSLSDHLANEMETYSLRSNIELKKALTDFCDSYGLVCNKPTVWVLHYLNTSGASCESRIIGVYATKTDGTDAIEKQLGGRIHSKGIFKREAGNNVQYIWSYYSVAELKKMMDAFDAWEGKGVSYWRVPHELIECWTLEERPLLGSLRHMAPIRKRRLITFNEADESVNYKTGPKPVRFLGPSTSTQIKVKNSASVTVSPASAIQTSAGATANRFQSGSRRKAAQRSAPSRATALVGTGAPGHPQASPGAASAENGGTHLPPAKVLLSDKKPTPQRVIKLKRTPLCATAPCLPSPTATRQANSLKPLPGEAARALGVRTENGKNKGN", "length": 426 }, "evidence": [ { "id": "A0A8V1A425", "url": "https://omabrowser.org/oma/group/A0A8V1A425/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "protein homooligomerization", "id": "GO:0051260", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051260", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A425", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A425" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 300, "end_pos": 302, "annotation": "n_glycosylation_sequon" }, { "start_pos": 357, "end_pos": 359, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1A425", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A425" }, { "id": "PF19321", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19321" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BTB/POZ", "eco_id": "ECO_0000259", "start_pos": 113, "end_pos": 418, "start_aa": "Tyr", "end_aa": "Ala", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1A425", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A425" }, { "id": "PF02214", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02214" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Potassium channel tetramerisation-type BTB", "eco_id": "ECO_0000259", "start_pos": 13, "end_pos": 97, "start_aa": "Leu", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 300, "end_pos": 302 }, { "start_pos": 357, "end_pos": 359 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A427-1", "uniprot_ac": "A0A8V1A427", "uniprot_id": "A0A8V1A427_CHICK", "mass": { "chemical_mass": 201788.0, "monoisotopic_mass": 201788.0 }, "refseq": {}, "gene_names": [ { "name": "NUP210L", "type": "recommended", "evidence": [ { "id": "A0A8V1A427", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A427" } ] } ], "protein_names": [ { "name": "Nucleoporin 210 like", "type": "synonym", "evidence": [ { "id": "A0A8V1A427", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A427/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A427", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A427" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NUP210L", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A427", "locus": { "chromosome": "25", "start_pos": 1853183, "end_pos": 1874533, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027370", "url": "https://www.ensembl.org/id/ENSGALG00010027370" } ] } } ], "crossref": [ { "id": "IPR003343", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003343", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008964", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008964", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045197", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045197", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055094", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055094", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055095", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055095", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055096", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055096", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055097", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055097", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055098", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055098", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055099", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055099", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056897", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056897", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056898", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056898", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056899", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056899", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057586", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057586", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058779", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058779", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A427", "url": "https://www.orthodb.org/?gene=A0A8V1A427", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A8Y0", "url": "https://www.orthodb.org/?gene=A0A8V1A8Y0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AEC8", "url": "https://www.orthodb.org/?gene=A0A8V1AEC8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AGD4", "url": "https://www.orthodb.org/?gene=A0A8V1AGD4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AGD9", "url": "https://www.orthodb.org/?gene=A0A8V1AGD9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23019", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23019", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23019:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23019:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02368", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02368", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22957", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22957", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22959", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22959", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22962", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22962", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22963", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22963", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22967", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22967", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22969", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22969", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24902", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24902", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24935", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24935", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24991", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24991", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25354", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25354", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF26181", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26181", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF26182", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26182", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF26183", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26183", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF26184", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26184", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1A427", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A427", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A427-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A427-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A8Y0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8Y0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A8Y0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8Y0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AEC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEC8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AEC8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEC8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGD4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGD4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGD4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGD4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGD9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGD9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGD9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGD9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRRARRFSLLALVLFVVVPSCAFKLNVPKVLLPFSQEMRVPFVLEAEGGCYSWHSMHYNVVAVEPLYENGAACSQKALLSPQSTQPTKLSSAVIAEEHVTGHVLRCDVMVDVIDSIEVLSRTREIYVEDSPLELAVRALDVKGNTFSSLSGMAFEWSVAKDEDVDSVELSDKIRILKYSEADYSPPDHIVELERAEKQGDRILVSGITTGAAVVKVRIHESTYKKVAAAVVRLLVLENIVLIPAHDVHLLVGAFIKYRVAKVVQGKITELEYPLEHYELELRDQVAAPGGSELLPVANLEGKTAAVRAVQLGQSSLVVVHRNVHMRAASGLPNCTIYVVEAGFLGFSVYPGDRWVLEVQREYAITVEVYDRDSTKVYLSDNLRITHSFSKEYFEELTSSPNGSYHVVRVLKDGTTGIRAELVSVLQQVREKDALISREQEVKMYHPIRLSRPLLAFPWHPTEVLYQYRLQVEGGSGNFSWISSNQTVATVTIKGAVSGGLARGHCTVQARDAQNPFHYVFVEPLAKLELMPLRADVEVGHTLAAPLQAYFTHRETRQYTAFTDCSLLPLEISMEKRGVFVLAEGGNRKPDWTFCSSLQIEARSVGHTLLTVSVNVHEQYLETSAMFAAYEPLKAVNPVEMALVTWKAAKEIVFEGGPGPWVLEPSRFFSELTVEHKDKIEVVQIRLPTQRKVNQYVYRAVCLELGEQVLTFRAGNRAGLLNPAPAVEAAMVTFICASPASMSMSPVYGALRAVPPCLLPQHSKQLIPISSRRSTVLELAVFDGQQRKFDNFSSLVLQWKSSNRSLAHFSDSGATRMVLKDDGSGQTRLHGTAGLWRTSFTAASGLFTSVEFLLVEDVMVLPDNVTVYNHPAVKELFSLVEGSGYFLVNSSKEGIVNMRYLEADSVTPLQPGFLSLGIHDSCLASLAPVAAHVRVSDMHEVEVDLSEKAEIGRSILATVRVLGFQRLPLQSKYFKYMKLQLQAASPIVTLVQVEEVGEYSQLHTLHAVAVGQTTLVATAWDKMGRKITSAPRKIEVFPPFKLIPRKITLIPHNVMQVMSEGGPQPQSIVHFSVTNCSVAEVSCLGHITAKAVGTTTIQGTIQVVSEDTGRVTVFSQDQVELEVIPLKAVRIHVPSTRLITGTEMPVFVVGLNNMLTPFSFSNANPELSFQWSVSKRDVLELLPRHRKVSIQLPAQNNVAMVVYTRAAGRTSIRVKVQCLNASAGQFEGNVTELTDEIQVLVFEKLFVFSPLFSTEQILMSTNSQLKLYTNREGAAFVSFQILQCYPNSSVLEERDQGLLRAGPITGIAALEVTSLELFGVNQTIVTSIQVAPISYLRISVSPQIYTTGGVSLAAFPLGMSLLITVEFYNSIGEKFHAQHAQLHLSVNRDDLLLIRPANKNHSYVAQAVSRGVTLLTVQDRKRPGVVDYIPVPVECAIQPELPRALAVGDVVCFSSPLVSQEGDPGTWHVSPPAVLTIDSASGAALAKSSGTAMVFHDIPGIVNTYREVFPTALQGCPRRVPDSGFPMGKPEWQLYLNCFVSWGQNLVLLRVRGSCSSAQVSAIAQRLVPQSRLQCHLKFSSTTVGVPAGDVFLVSPEFSTQEGLYVCVITAKPQPSEALLALSTTNTSVHVVVSLSSDTQSILIPFLPAFYLGQSELVFSATQLTAVLSVLGAEQVLEELQVQSSSPAVAVTPPEFFSNKPGLVRYTVRVLNLSSLQQRPAASITVSCALTGQRAVVTARAVAGESGGAALKQLAGSYQILLFTLFAVLGSTAVTYLAYNAFLSRLQTLPLIYVSNAAVPQAGEPTAVCSAIPNHPMRGIHYRPPEEQLQNCSRTQLGLWSVQS", "length": 1843, "header": "tr|A0A8V1A427-1|A0A8V1A427_CHICK Isoform 1 of Nucleoporin 210 like OS=Gallus gallus OX=9031 GN=NUP210L PE=3 SV=1 CANONICAL=A0A8V1A427-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A427-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A427/entry#A0A8V1A427-1", "sequence": { "sequence": "MRRARRFSLLALVLFVVVPSCAFKLNVPKVLLPFSQEMRVPFVLEAEGGCYSWHSMHYNVVAVEPLYENGAACSQKALLSPQSTQPTKLSSAVIAEEHVTGHVLRCDVMVDVIDSIEVLSRTREIYVEDSPLELAVRALDVKGNTFSSLSGMAFEWSVAKDEDVDSVELSDKIRILKYSEADYSPPDHIVELERAEKQGDRILVSGITTGAAVVKVRIHESTYKKVAAAVVRLLVLENIVLIPAHDVHLLVGAFIKYRVAKVVQGKITELEYPLEHYELELRDQVAAPGGSELLPVANLEGKTAAVRAVQLGQSSLVVVHRNVHMRAASGLPNCTIYVVEAGFLGFSVYPGDRWVLEVQREYAITVEVYDRDSTKVYLSDNLRITHSFSKEYFEELTSSPNGSYHVVRVLKDGTTGIRAELVSVLQQVREKDALISREQEVKMYHPIRLSRPLLAFPWHPTEVLYQYRLQVEGGSGNFSWISSNQTVATVTIKGAVSGGLARGHCTVQARDAQNPFHYVFVEPLAKLELMPLRADVEVGHTLAAPLQAYFTHRETRQYTAFTDCSLLPLEISMEKRGVFVLAEGGNRKPDWTFCSSLQIEARSVGHTLLTVSVNVHEQYLETSAMFAAYEPLKAVNPVEMALVTWKAAKEIVFEGGPGPWVLEPSRFFSELTVEHKDKIEVVQIRLPTQRKVNQYVYRAVCLELGEQVLTFRAGNRAGLLNPAPAVEAAMVTFICASPASMSMSPVYGALRAVPPCLLPQHSKQLIPISSRRSTVLELAVFDGQQRKFDNFSSLVLQWKSSNRSLAHFSDSGATRMVLKDDGSGQTRLHGTAGLWRTSFTAASGLFTSVEFLLVEDVMVLPDNVTVYNHPAVKELFSLVEGSGYFLVNSSKEGIVNMRYLEADSVTPLQPGFLSLGIHDSCLASLAPVAAHVRVSDMHEVEVDLSEKAEIGRSILATVRVLGFQRLPLQSKYFKYMKLQLQAASPIVTLVQVEEVGEYSQLHTLHAVAVGQTTLVATAWDKMGRKITSAPRKIEVFPPFKLIPRKITLIPHNVMQVMSEGGPQPQSIVHFSVTNCSVAEVSCLGHITAKAVGTTTIQGTIQVVSEDTGRVTVFSQDQVELEVIPLKAVRIHVPSTRLITGTEMPVFVVGLNNMLTPFSFSNANPELSFQWSVSKRDVLELLPRHRKVSIQLPAQNNVAMVVYTRAAGRTSIRVKVQCLNASAGQFEGNVTELTDEIQVLVFEKLFVFSPLFSTEQILMSTNSQLKLYTNREGAAFVSFQILQCYPNSSVLEERDQGLLRAGPITGIAALEVTSLELFGVNQTIVTSIQVAPISYLRISVSPQIYTTGGVSLAAFPLGMSLLITVEFYNSIGEKFHAQHAQLHLSVNRDDLLLIRPANKNHSYVAQAVSRGVTLLTVQDRKRPGVVDYIPVPVECAIQPELPRALAVGDVVCFSSPLVSQEGDPGTWHVSPPAVLTIDSASGAALAKSSGTAMVFHDIPGIVNTYREVFPTALQGCPRRVPDSGFPMGKPEWQLYLNCFVSWGQNLVLLRVRGSCSSAQVSAIAQRLVPQSRLQCHLKFSSTTVGVPAGDVFLVSPEFSTQEGLYVCVITAKPQPSEALLALSTTNTSVHVVVSLSSDTQSILIPFLPAFYLGQSELVFSATQLTAVLSVLGAEQVLEELQVQSSSPAVAVTPPEFFSNKPGLVRYTVRVLNLSSLQQRPAASITVSCALTGQRAVVTARAVAGESGGAALKQLAGSYQILLFTLFAVLGSTAVTYLAYNAFLSRLQTLPLIYVSNAAVPQAGEPTAVCSAIPNHPMRGIHYRPPEEQLQNCSRTQLGLWSVQS", "length": 1843, "header": "tr|A0A8V1A427-1|A0A8V1A427_CHICK Isoform 1 of Nucleoporin 210 like OS=Gallus gallus OX=9031 GN=NUP210L PE=3 SV=1 CANONICAL=A0A8V1A427-1" }, "locus": { "chromosome": "25", "start_pos": 1874480, "end_pos": 1853416, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066370.1", "url": "https://www.ensembl.org/id/ENSGALT00010066370.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040636.1", "url": "https://www.ensembl.org/id/ENSGALP00010040636.1" } ] } }, { "isoform_ac": "A0A8V1A8Y0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A427/entry#A0A8V1A8Y0-1", "sequence": { "sequence": "MRAASGLPNCTIYVVEAGFLGFSVYPGDRWVLEVQREYAITVEVYDRDSTKVYLSDNLRITHSFSKEYFEELTSSPNGSYHVVRVLKDGTTGIRAELVSVLQQGGSGPSFPTVISREQEVKMYHPIRLSRPLLAFPWHPTEVLYQYRLQVEGGSGNFSWISSNQTVATVTIKGAVSGGLARGHCTVQARDAQNPFHYVFVEPLAKLELMPLRADVEVGHTLAAPLQAYFTHRETRQYTAFTDCSLLPLEISMEKRGVFVLAEGGNRKPDWTFCSSLQIEARSVGHTLLTVSVNVHEQYLETSAMFAAYEPLKAVNPVEMALVTWKAAKEIVFEGGPGPWVLEPSRFFSELTVEHKDKIEVVQIRLPTQRKVNQYVYRAVCLELGEQVLTFRAGNRAGLLNPAPAVEAAMVTFICASPASMSMSPVYGALRAVPPCLLPQHSKQLIPISSRRSTVLELAVFDGQQRKFDNFSSLVLQWKSSNRSLAHFSDSGATRMVLKDDGSGQTRLHGHQLLEVHQIKGTVRVEVSFVKYRTGGGPQAASGLFTSVEFLLVEDVMVLPDNVTVYNHPAVKELFSLVEGSGYFLVNSSKEGIVNMRYLEADSAIEVTPLQPGFLSLGIHDSCLASLAPVAAHVRVSDMHEVEVDLSEKAEIGRSILATVRVLGFQRLPLQSKYFKYMKLQLQAASPIVTLVQVEEVGEYSQLHTLHAVAVGQTTLVATAWDKMGRKITSAPRKIEVMSEGGPQPQSIVHFSVTNCSVAEVSCLGHITAKAVGTTTIQGTIQVVSEDTGRVTVFSQDQVELEVIPLKAVRIHVPSTRLITGTEMPVFVVGLNNMLTPFSFSNANPELSFQWSVSKRDVLELLPRHRKVSIQLPAQNNVAMVVYTRAAGRTSIRVKVQCLNASAGQFEGNVTELTDEIQVLVFEKLFVFSPLFSTEQILMSTNSQLKLYTNREGAAFVSFQILQCYPNSSVLEERDQGLLRAGPITGIAALEVTSLELFGVNQTIVTSIQVAPISYLRISVSPQIYTTGGVSLAAFPLGMSLLITVEFYNSIGEKFHAQHAQLHLSVNRDDLLLIRPANKNHSYVAQAVSRGVTLLTVQDRKRPGVVDYIPVPVECAIQPELPRALAVGDVVCFSSPLVSQEGDPGTWHVSPPAVLTIDSASGAALAKSSGTAMVFHDIPGIVNTYREVSVNGSSRLHLRTGQKSYLTNAPNSSAFHVLIATSSGRETLQGSCSSAQVSAIAQRLVPQSRLQCHLKFSSTTVGVPAGDVFLVSPEFSTQEGLYVCVITAKPQPSEALLALSTTNTSVHVVVSLSSDTQSILIPFLPAFYLGQSELVFSATQLTAVLSVLGAEQVLEELQVQSSSPAVAVTPPEFFSNKPGLVRYTVRVLNLSSLQQRPAASITVSCALTGQRAVVTARAVAGECPPGQRGAVGIHQQLAGSYQILLFTLFAVLGSTAVTYLAYNAFLSRLQTLPLIYVSNAAVPQAGYSHPPGPTQGGSRTQLGLWSVQS", "length": 1508, "header": "tr|A0A8V1A8Y0-1|A0A8V1A8Y0_CHICK Computationally mapped isoform of Nucleoporin 210 like OS=Gallus gallus OX=9031 GN=NUP210L PE=4 SV=1 CANONICAL=A0A8V1A427-1" }, "locus": { "chromosome": "25", "start_pos": 1871267, "end_pos": 1853416, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066367.1", "url": "https://www.ensembl.org/id/ENSGALT00010066367.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040633.1", "url": "https://www.ensembl.org/id/ENSGALP00010040633.1" } ] } }, { "isoform_ac": "A0A8V1AEC8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A427/entry#A0A8V1AEC8-1", "sequence": { "sequence": "MRRARRFSLLALVLFVVVPSCAFKLNVPKVLLPFSQEMRVPFVLEAEGGCYSWHSMHYNVVAVEPLYENGAACSQKALLSPQSTQPTKLSSAVIAEEHVTGHVLRCDVMVDVIDSIEVLSRTREIYVEDSPLELAVRALDVKGNTFSSLSGMAFEWSVAKDEDVDSCFCFLVRILKYSEADYSPPDHIVELERAEKQGDRILVSGITTGAAVVKVRIHESTYKKVAAAVVRLLVLENIVLIPAHDVHLLVGAFIKYRVAKVVQGKITELEYPLEHYELELRDQVAAPGGSELLPVANLEGKTAAVRAVQLGQSSLVVVHRSILLAASGLPNCTIYVVEAGFLGFSVYPGDRWVLEVQREYAITVEVYDRDSTKVYLSDNLRITHSFSKEYFEELTSSPNGSYHVVRVLKDGTTGIRAELVSVLQQVREKDARDFLQNQEVKMYHPIRLSRPLLAFPWHPTEVLYQYRLQVEGGSGNFSWISSNQTVATVTIKGAVSGGLARGHCTVQARDAQNPFHYAEIQESLSFIIFFWAVYCSEMPSCPGLETESFCLKVKVCLRSVLGNRKPDWTFCSSLQIEARSVGHTLLTVSVNVHEQYLETSAMFAAYEPLKAVNPVEMALVTWKAAKEIVFEGGPGPWVLEPSRFFSELTVEHKDKIEVVQIRLPTQRKVNQYVYRAVCLELGEQVLTFRAGNRAGLLNPAPAVEAAMVTFICASPASMSMSPVYGAPGSELSMELLVCVQIPISSRRSTVLELAVFDGQQRKFDNFSSLVLQWKSSNRSLAHFSDSGATRMVLKDDGSGQTRLHGTAGLWRTSFTAASGLFTSVEFLLVEDVMVLPDNVTVYNHPAVKVTAPFTAAEIGRSILATVRVLGFQRLPLQSKYFKYMKLQLQAASPIVTLVQVEEVGEYSQLHTLHAVAVGQTTLVATAWDKMGRKITSAPRKIEVFPPFKLIPRKITLIPHNVMQVMSEGGPQPQSIVHFSVTNCSVAEVSCLGHITAKAVGTTTIQGTIQVVSEDTGRVTVFSQDQVELEVIPLKAVRIHVPSTRLITGTEMPVFVVGLNNMLTPFSFSNANPELSFQWSVSKRDVLELLPRHRKVSIQLPAQNNVAMVVYTRAAGRTSIRVKVQCLNASAGQFEGNVTELTDEIQVLVCCASLTEPSCFCSWLREGAAFVSFQILQCYPNSSVLEERDQGLLRAGPITGIAALEVTSLELFGVNQTIVTSIQVAPISYLRISVSPQIYTTGGVSLAAFPLGMSLLITVEFYNSIGEKFHAQHIFVFRDDLLLIRPANKNHSYVAQAVSRGVTLLTVQDRKRPGVVDYIPVPVECAIQPELPRALAVGDVVCFSSPLVSQEGDPGTWHVSPPAVLTIDSASGAALAKSSGTAMVFHDIPGIVNTYREVFPTALQGTDSTQRVVTH", "length": 1414, "header": "tr|A0A8V1AEC8-1|A0A8V1AEC8_CHICK Computationally mapped isoform of Nucleoporin 210 like OS=Gallus gallus OX=9031 GN=NUP210L PE=3 SV=1 CANONICAL=A0A8V1A427-1" }, "locus": { "chromosome": "25", "start_pos": 1874480, "end_pos": 1856065, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066368.1", "url": "https://www.ensembl.org/id/ENSGALT00010066368.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040634.1", "url": "https://www.ensembl.org/id/ENSGALP00010040634.1" } ] } }, { "isoform_ac": "A0A8V1AGD4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A427/entry#A0A8V1AGD4-1", "sequence": { "sequence": "MRAASGLPNCTIYVVEAGFLGFSVYPGDRWVLEVQREYAITVEVYDRDSTKVYLSDNLRITHSFSKEYFEELTSSPNGSYHVVRVLKDGTTGIRAELVSVLQQGGSGPSFPTVISREQEVKMYHPIRLSRPLLAFPWHPTEVLYQYRLQVEGGSGNFSWISSNQTVATVTIKGAVSGGLARGHCTVQARDAQNPFHYVFVEPLAKLELMPLRADVEVGHTLAAPLQAYFTHRETRQYTAFTDCSLLPLEISMEKRGVFVLAEGGNRKPDWTFCSSLQIEARSVGHTLLTVSVNVHEQYLETSAMFAAYEPLKAVNPVEMALVTWKAAKEIVFEGGPGPWVLEPSRFFSELTVEHKDKIEVVQIRLPTQRKVNQYVYRAVCLELGEQVLTFRAGNRAGLLNPAPAVEAAMVTFICASPASMSMSPVYGALRAVPPCLLPQHSKQLIPISSRRSTVLELAVFDGQQRKFDNFSSLVLQWKSSNRSLAHFSDSGATRMVLKDDGSGQTRLHGHQLLEVHQIKGTVRVEVSFVKYRTGGGPQAASGLFTSVEFLLVEDVMVLPDNVTVYNHPAVKELFSLVEGSGYFLVNSSKEGIVNMRYLEADSAIEVTPLQPGFLSLGIHDSCLASLAPVAAHVRVSDMHEVEVDLSEKAEIGRSILATVRVLGFQRLPLQSKYFKYMKLQLQAASPIVTLVQVEEVGEYSQLHTLHAVAVGQTTLVATAWDKMGRKITSAPRKIEVFPPFKLIPRKITLIPHNVMQVMSEGGPQPQSIVHFSVTNCSVAEVSCLGHITAKAVGTTTIQGTIQVVSEDTGRVTVFSQDQVELEVIPLKAVRIHVPSTRLITGTEMPVFVVGLNNMLTPFSFSNANPELSFQWSVSKRDVLELLPRHRKVSIQLPAQNNVAMVVYTRAAGRTSIRVKVQCLNASAGQFEGNVTELTDEIQVLVFEKLFVFSPLFSTEQILMSTNSQLKLYTNREGAAFVSFQILQCYPNSSVLEERDQGLLRAGPITGIAALEVTSLELFGVNQTIVTSIQVAPISYLRISVSPQIYTTGGVSLAAFPLGMSLLITVEFYNSIGEKFHAQHAQLHLSVNRDDLLLIRPANKNHSYVAQAVSRGVTLLTVQDRKRPGVVDYIPVPVECAIQPELPRALAVGDVVCFSSPLVSQEGDPGTWHVSPPAVLTIDSASGAALAKSSGTAMVFHDIPGIVNTYREVSVNGSSRLHLRTGQKSYLTNAPNSSAFHVLIATSSGRETLQGSCSSAQVSAIAQRLVPQSRLQCHLKFSSTTVGVPAGDVFLVSPEFSTQEGLYVCVITAKPQPSEALLALSTTNTSVHVVVSLSSDTQSILIPFLPAFYLGQSELVFSATQLTAVLSVLGAEQVLEELQVQSSSPAVAVTPPEFFSNKPGLVRYTVRVLNLSSLQQRPAASITVSCALTGQRAVVTARAVAGECPPGQRGAVGIHQQLAGSYQILLFTLFAVLGSTAVTYLAYNAFLSRLQTLPLIYVSNAAVPQAGYSHPPGPTQGGSRTQLGLWSVQS", "length": 1529, "header": "tr|A0A8V1AGD4-1|A0A8V1A427_CHICK Computationally mapped isoform of Nucleoporin 210 like OS=Gallus gallus OX=9031 GN=NUP210L PE=3 SV=1 CANONICAL=A0A8V1A427-1" }, "locus": { "chromosome": "25", "start_pos": 1871267, "end_pos": 1853416, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066366.1", "url": "https://www.ensembl.org/id/ENSGALT00010066366.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040632.1", "url": "https://www.ensembl.org/id/ENSGALP00010040632.1" } ] } }, { "isoform_ac": "A0A8V1AGD9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A427/entry#A0A8V1AGD9-1", "sequence": { "sequence": 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"id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nuclear pore", "id": "GO:0005643", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005643", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A427", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A427" } ], "pmid": "" }, { "name": "nuclear membrane", "id": "GO:0031965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031965", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A427", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A427" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1074, "end_pos": 1076, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1219, "end_pos": 1221, "annotation": 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This record is derived from a genomic sequence (NC_052557.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004934954.1. 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Classification" ] }, { "id": "A0A8V1A440", "url": "https://www.orthodb.org/?gene=A0A8V1A440", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ABJ0", "url": "https://www.orthodb.org/?gene=A0A8V1ABJ0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ABJ3", "url": "https://www.orthodb.org/?gene=A0A8V1ABJ3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ABJ7", "url": "https://www.orthodb.org/?gene=A0A8V1ABJ7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45789", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45789", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45789:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45789:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00505", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00505", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-3769402", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3769402", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_004934954", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004934954", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1A440", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A440", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A440-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A440-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ABJ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABJ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ABJ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABJ0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ABJ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABJ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ABJ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABJ3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ABJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABJ7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ABJ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABJ7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSMRSPVSPHLELDGAGSMVNCSIKTEEKKESGYESPPGAAPSTEPHPNDPPGPPPREGTDPQALPQESCSPAGDALEPRCSAFEPAVGSQEKLDFNRNLKEVMPTIEKLLSSDWKERLLGRNAAETKEVKGTQESLAEKELQLLVMINQLSTLRDQLLTAHSEQKNMAAMLFEKQQQQMELARQQQEQIAKQQQQLIQQQHKINLLQQQIQQVNMPYVMIPAFTPSHQPLPVTQDPQIALPIQPIPCKPVDYPVQLLHSPPPPTLKRPSGSGHLQMQETSQPLNLTAKPKGSELPSASSSPSLKMSSCQSLTPSHGAVRDLQSSPSNLPLGFLGEGDAITKAIQDARQLLHGHSGAMEGALSHPYRKDHVGIDASPVKERMEETPTHRLDEALLSCEMDGTRHFPESRNNNHIKRPMNAFMVWAKDERRKILQAFPDMHNSSISKILGSRWKSMTNQEKQPYYEEQARLSRQHLEKYPDYKYKPRPKRTCIVEGKRLRVGEYKALMRNRRQDARQGYLIGPQGSQLPPGSSDVLYPRPVGMQLPSPLMEHYLPRGVDPSMPVIISARSLKEGDGGGDDGHSVADGEMYRYSEEEDSEGEEKSDGELVVLTD", "length": 612, "header": "tr|A0A8V1A440-1|A0A8V1A440_CHICK Isoform 1 of SRY-box transcription factor 13 OS=Gallus gallus OX=9031 GN=SOX13 PE=4 SV=1 CANONICAL=A0A8V1A440-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A440-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A440/entry#A0A8V1A440-1", "sequence": { "sequence": "MSMRSPVSPHLELDGAGSMVNCSIKTEEKKESGYESPPGAAPSTEPHPNDPPGPPPREGTDPQALPQESCSPAGDALEPRCSAFEPAVGSQEKLDFNRNLKEVMPTIEKLLSSDWKERLLGRNAAETKEVKGTQESLAEKELQLLVMINQLSTLRDQLLTAHSEQKNMAAMLFEKQQQQMELARQQQEQIAKQQQQLIQQQHKINLLQQQIQQVNMPYVMIPAFTPSHQPLPVTQDPQIALPIQPIPCKPVDYPVQLLHSPPPPTLKRPSGSGHLQMQETSQPLNLTAKPKGSELPSASSSPSLKMSSCQSLTPSHGAVRDLQSSPSNLPLGFLGEGDAITKAIQDARQLLHGHSGAMEGALSHPYRKDHVGIDASPVKERMEETPTHRLDEALLSCEMDGTRHFPESRNNNHIKRPMNAFMVWAKDERRKILQAFPDMHNSSISKILGSRWKSMTNQEKQPYYEEQARLSRQHLEKYPDYKYKPRPKRTCIVEGKRLRVGEYKALMRNRRQDARQGYLIGPQGSQLPPGSSDVLYPRPVGMQLPSPLMEHYLPRGVDPSMPVIISARSLKEGDGGGDDGHSVADGEMYRYSEEEDSEGEEKSDGELVVLTD", "length": 612, "header": "tr|A0A8V1A440-1|A0A8V1A440_CHICK Isoform 1 of SRY-box transcription factor 13 OS=Gallus gallus OX=9031 GN=SOX13 PE=4 SV=1 CANONICAL=A0A8V1A440-1" }, "locus": { "chromosome": "26", "start_pos": 1750021, "end_pos": 1743788, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010062800.1", "url": "https://www.ensembl.org/id/ENSGALT00010062800.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038804.1", "url": "https://www.ensembl.org/id/ENSGALP00010038804.1" } ] } }, { "isoform_ac": "A0A8V1ABJ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A440/entry#A0A8V1ABJ0-1", "sequence": { "sequence": "MSMRSPVSPHLELDGAGSMVNCSIKTEEKKESGYESPPGAAPSTEPHPNDPPGPPPREGTDPQALPQESCSPAGDALEPRCSAFEPAVGSQEKLDFNRNLKEGTQESLAEKELQLLVMINQLSTLRDQLLTAHSEQKNMAAMLFEKQQQQMELARQQQEQIAKQQQQLIQQQHKINLLQQQIQVNMPYVMIPAFTPSHQPLPVTQDPQIALPIQPIPCKPVDYPVQLLHSPPPPTLKRPSGSGHLQMQETSQPLNLTAKPKGSELPSASSSPSLKMSSCQSLTPSHGAVRDLQSSPSNLPLGFLGEGDAITKAIQDARQLLHGHSGAMEGALSHPYRKDHVGIDASPVKERMEETPTHRLDEALLSCEMDGTRHFPESRNNNHIKRPMNAFMVWAKDERRKILQAFPDMHNSSISKILGSRWKSMTNQEKQPYYEEQARLSRQHLEKYPDYKYKPRPKRTCIVEGKRLRVGEYKALMRNRRQDARQGYLIGPQGSQLPPGSSDVLYPRPVGMQLPSPLMEHYLPRGVDPSMPVIISARSLKEGDGGGDDGHSVADGEMYRYSEEEDSEGEEKSDGELVVLTD", "length": 582, "header": "tr|A0A8V1ABJ0-1|A0A8V1ABJ0_CHICK Computationally mapped isoform of SRY-box transcription factor 13 OS=Gallus gallus OX=9031 GN=SOX13 PE=4 SV=1 CANONICAL=A0A8V1A440-1" }, "locus": { "chromosome": "26", "start_pos": 1750021, "end_pos": 1743788, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010062807.1", "url": "https://www.ensembl.org/id/ENSGALT00010062807.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038808.1", "url": "https://www.ensembl.org/id/ENSGALP00010038808.1" } ] } }, { "isoform_ac": "A0A8V1ABJ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A440/entry#A0A8V1ABJ3-1", "sequence": { "sequence": "MLDVLQSQTRALGVPGAVALAQGRCREGCWLVLGPLGWVRGKRSGGECSAQIASHKALMQLLSTCWKWSSAPPPRLSHHRGTRMSMRSPVSPHLELDGAGSMVNCSIKTEEKKESGYESPPGAAPSTEPHPNDPPGPPPREGTDPQALPQESCSPAGDALEPRCSAFEPAVGSQEKLDFNRNLKEVMPTIEKLLSSDWKERLLGRNAAETKEVKGTQESLAEKELQLLVMINQLSTLRDQLLTAHSEQKNMAAMLFEKQQQQMELARQQQEQIAKQQQQLIQQQHKINLLQQQIQQVNMPYVMIPAFTPSHQPLPVTQDPQIALPIQPIPCKPVDYPVQLLHSPPPPTLKRPSGSGHLQMQETSQPLNLTAKPKGSELPSASSSPSLKMSSCQSLTPSHGAVRDLQSSPSNLPLGFLGEGDAITKAIQDARQLLHGHSGAMEGALSHPYRKDHVGIDASPVKERMEETPTHRLDEALLSCEMDGTRHFPESRNNNHIKRPMNAFMVWAKDERRKILQAFPDMHNSSISKILGSRWKSMTNQEKQPYYEEQARLSRQHLEKYPDYKYKPRPKRTCIVEGKRLRVGEYKALMRNRRQDARQGYLIGPQGSQLPPGSSDVLYPRPVGMQLPSPLMEHYLPRGVDPSMPVIISARSLKEGDGGGDDGHSVADGEMYRYSEEEDSEGEEKSDGELVVLTD", "length": 695, "header": "tr|A0A8V1ABJ3-1|A0A8V1ABJ3_CHICK Computationally mapped isoform of SRY-box transcription factor 13 OS=Gallus gallus OX=9031 GN=SOX13 PE=4 SV=1 CANONICAL=A0A8V1A440-1" }, "locus": { "chromosome": "26", "start_pos": 1750021, "end_pos": 1734005, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010062814.1", "url": "https://www.ensembl.org/id/ENSGALT00010062814.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038813.1", "url": "https://www.ensembl.org/id/ENSGALP00010038813.1" } ] } }, { "isoform_ac": "A0A8V1ABJ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A440/entry#A0A8V1ABJ7-1", "sequence": { "sequence": "MSMRSPVSPHLELDGAGSMVNCSIKTEEKKESGYESPPGAAPSTEPHPNDPPGPPPREGTDPQALPQESCSPAGDALEPRCSAFEPAVGSQEKLDFNRNLKEVMPTIEKLLSSDWKERLLGRNAAETKEVKGTQESLAEKELQLLVMINQLSTLRDQLLTAHSEQKNMAAMLFEKQQQQMELARQQQEQIAKQQQQLIQQQHKINLLQQQIQVKVGDTPVPTRRDGQWGHRPATPSHNHYPCFSFLQQVNMPYVMIPAFTPSHQPLPVTQDPQIALPIQPIPCKPVDYPVQLLHSPPPPTLKRPSGSGHLQMQETSQPLNLTAKPKGSELPSASSSPSLKMSSCQSLTPSHGAVRDLQSSPSNLPLGFLGEGDAITKAIQDARQLLHGHSGAMEGALSHPYRKDHVGIDASPVKERMEETPTHRLDEALLSCEMDGTRHFPESRNNNHIKRPMNAFMVWAKDERRKILQAFPDMHNSSISKILGSRWKSMTNQEKQPYYEEQARLSRQHLEKYPDYKYKPRPKRTCIVEGKRLRVGEYKALMRNRRQDARQGYLIGMPVIISARSLKEGDGGGDDGHSVADGEMYRYSEEEDSEGEEKSDGELVVLTD", "length": 608, "header": "tr|A0A8V1ABJ7-1|A0A8V1ABJ7_CHICK Computationally mapped isoform of SRY-box transcription factor 13 OS=Gallus gallus OX=9031 GN=SOX13 PE=4 SV=1 CANONICAL=A0A8V1A440-1" }, "locus": { "chromosome": "26", "start_pos": 1750021, "end_pos": 1743788, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010062822.1", "url": "https://www.ensembl.org/id/ENSGALT00010062822.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038818.1", "url": "https://www.ensembl.org/id/ENSGALP00010038818.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:419820", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419820", "resource": "KEGG Pathway" }, { "id": "R-GGA-3769402", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3769402", "resource": "Reactome", "description": "Deactivation of the beta-catenin transactivating complex" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8D2CDI2-1", "protein_name": "SRY-box transcription factor 13", "gene_name": "SOX13", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSMRSPGSAQLALDDAGTMVNCTVKSEGKKEPCHEAPQGSATAAEPQPGDPARVPQDGADPQAPAQDSSSLESSGSPEPKRPGGPEAASGSQEKLDFNRNLKEVVPAIEKLLSSDWKERFLGRSSVEAKDVKGTQESLAEKELQLLVMIHQLSTLRDQLLTAHSEQKNMAAMLFEKQQQQMELARQQQEQIAKQQQQLIQQQHKINLLQQQIQVNMPYVMIPAFPPSHQPLPVTPDSQLALPIQPIPCKPVEYPLQLLHSPPAPVVKRPGALSAHHPLQEPSQPLNLTAKPKAPELPNTSSSPSLKMSNCGPRPPSHGAPTRDLQASPPSLPLGFLGEGDAVTKAIQDARQLLHGHSGALESSPNTPFRKDLISLDTSPAKERLEENCVHPLEEAMLGCDVDGSRHFPESRNSSHIKRPMNAFMVWAKDERRKILQAFPDMHNSSISKILGSRWKSMTNQEKQPYYEEQARLSRQHLEKYPDYKYKPRPKRTCIVEGKRLRVGEYKALMRTRRQDARQSYATPPQAGQVQMSPSDVLYPRVAGVPLAQPLVEHYVPRSLDPNMPVIVNTCSLREEGEGTEDRHSVADGEMYRFSEEEDSEGEEKSDGELVVLTD", "length": 614 }, "evidence": [ { "id": "A0A8V1A440", "url": "https://omabrowser.org/oma/group/A0A8V1A440/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "D4A8S0-1", "protein_name": "SRY-box transcription factor 13", "gene_name": "Sox13", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSVQSPVSVQLAPDSASTMVNCTVKSEEKKEPCHEAPQGTATAVEPQPGDPALASQDATNSKAPAQDCASPQSSGSPDPKRPAASEAASGSQERLDFNRNLQEVVPAIEKLLSSDWKERFLGRSSVEAKDVKGTQESLAEKELQLLVMIHQLSALRDQLLTAHSEQKNMAAMLFEKQQQQMELARQQQEQIAKQQQQLIQQQHKINLLQQQIQQVNMPYVMIPAFPSSHQPLPVTPDSQLALPIQPIPCKPVEYPLQLLHSPPAPVVKRPGVATHHPLQEPPQPLNLTAKPKVSELPNTSSSPSLKMNSCGPRPSSHGAPTRDLQSSPPNLPLGFLGEGDAVTKAIQDARQLLHSHSGALENSPSAPFRKDLISLDSSPAKERLEENCVHPLEEAMLGCDVDGSRHFSESRNSSHIKRPMNAFMVWAKDERRKILQAFPDMHNSSISKILGSRWKSMTNQEKQPYYEEQARLSRQHLEKYPDYKYKPRPKRTCVVEGRRLRVGEYKALMRTRRQGARQSYAIPPQAGQAQVSSDILFPRAAGMPLARPLVEHYDPQGLDPNMPVIINTCSLREEGEGTDDRHSVADGEMYRYSEDEDSEGDEKSEEELVVLTD", "length": 613 }, "evidence": [ { "id": "A0A8V1A440", "url": "https://omabrowser.org/oma/group/A0A8V1A440/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q04891-1", "protein_name": "Transcription factor SOX-13", "gene_name": "Sox13", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSMQSPVSVQLAPDSASTMVNCTIKSEEKKEPCHEAPQGAAPAVETQPGDPALASQDATNAKAPPQDCASPESSGSPEPKRPAASEAASGSQERLDFNRNLQEVVPAIEKLLSSDWKERFLGRSNVEAKDVKGTQESLAEKELQLLVMIHQLSALRDQLLTAHSEQKNMAAMLFEKQQQQMELARQQQEQIAKQQQQLIQQQHKINLLQQQIQQVNMPYVMIPAFPPSHQPLPVTPDSQLALPIQPIPCKPVEYPLQLLHSPPAPVVKRSGVAAHHPLQEPPQPLNLTAKPKVPELPNTSSSPSLKMNSCGPRPASHGAPTRDLQSSPPSLPLGFLGEGDAVTKAIQDARQLLHSHSGALENSPNTPFRKDLISLDSSPAKERLEESCVHPLEEAMLSCDMDGSRHFSESRNSSHIKRPMNAFMVWAKDERRKILQAFPDMHNSSISKILGSRWKSMTNQEKQPYYEEQARLSRQHLEKYPDYKYKPRPKRTCVVEGRRLRVGEYKALMRTRRQGARQSYTIPPQAGQAQVSSDILFPRAAGLPLARPLVEHYDPQGLDPNMPVIINTCSLREEGEGTDDRHSVADGEMYRYSEDEDSEGDEKSDEELVVLTD", "length": 613 }, "evidence": [ { "id": "A0A8V1A440", "url": "https://omabrowser.org/oma/group/A0A8V1A440/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9UN79-1", "protein_name": "Transcription factor SOX-13", "gene_name": "SOX13", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSMRSPISAQLALDGVGTMVNCTIKSEEKKEPCHEAPQGSATAAEPQPGDPARASQDSADPQAPAQGNFRGSWDCSSPEGNGSPEPKRPGVSEAASGSQEKLDFNRNLKEVVPAIEKLLSSDWKERFLGRNSMEAKDVKGTQESLAEKELQLLVMIHQLSTLRDQLLTAHSEQKNMAAMLFEKQQQQMELARQQQEQIAKQQQQLIQQQHKINLLQQQIQQVNMPYVMIPAFPPSHQPLPVTPDSQLALPIQPIPCKPVEYPLQLLHSPPAPVVKRPGAMATHHPLQEPSQPLNLTAKPKAPELPNTSSSPSLKMSSCVPRPPSHGGPTRDLQSSPPSLPLGFLGEGDAVTKAIQDARQLLHSHSGALDGSPNTPFRKDLISLDSSPAKERLEDGCVHPLEEAMLSCDMDGSRHFPESRNSSHIKRPMNAFMVWAKDERRKILQAFPDMHNSSISKILGSRWKSMTNQEKQPYYEEQARLSRQHLEKYPDYKYKPRPKRTCIVEGKRLRVGEYKALMRTRRQDARQSYVIPPQAGQVQMSSSDVLYPRAAGMPLAQPLVEHYVPRSLDPNMPVIVNTCSLREEGEGTDDRHSVADGEMYRYSEDEDSEGEEKSDGELVVLTD", "length": 622 }, "evidence": [ { "id": "A0A8V1A440", "url": "https://omabrowser.org/oma/group/A0A8V1A440/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A440", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A440" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A440", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A440" } ], "pmid": "" }, { "name": "DNA-binding transcription repressor activity, RNA polymerase II-specific", "id": "GO:0001227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001227", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A440", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A440" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A440", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A440" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A440", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A440" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A440", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A440" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A440", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A440" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A440", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A440" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A440", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A440" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A440", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A440" } ], "pmid": "" }, { "name": "negative regulation of canonical Wnt signaling pathway", "id": "GO:0090090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090090", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A440", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A440" } ], "pmid": "" }, { "name": "positive regulation of gamma-delta T cell differentiation", "id": "GO:0045588", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045588", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A440", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A440" } ], "pmid": "" }, { "name": "cell fate commitment", "id": "GO:0045165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045165", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A440", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A440" } ], "pmid": "" }, { "name": "gamma-delta T cell differentiation", "id": "GO:0042492", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042492", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A440", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A440" } ], "pmid": "" }, { "name": "spinal cord oligodendrocyte cell differentiation", "id": "GO:0021529", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021529", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A440", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A440" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 21, "end_pos": 23, "annotation": "n_glycosylation_sequon" }, { "start_pos": 285, "end_pos": 287, "annotation": "n_glycosylation_sequon" }, { "start_pos": 441, "end_pos": 443, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1A440", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A440" }, { "id": "PS50118", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50118" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "HMG box", "eco_id": "ECO_0000259", "start_pos": 414, "end_pos": 482, "start_aa": "Ile", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 21, "end_pos": 23 }, { "start_pos": 285, "end_pos": 287 }, { "start_pos": 441, "end_pos": 443 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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} ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A441-1", "uniprot_ac": "A0A8V1A441", "uniprot_id": "A0A8V1A441_CHICK", "mass": { "chemical_mass": 140159.0, "monoisotopic_mass": 140159.0 }, "refseq": {}, "gene_names": [ { "name": "PPFIA4", "type": "recommended", "evidence": [ { "id": "A0A8V1A441", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A441" } ] } ], "protein_names": [ { "name": "PTPRF interacting protein alpha 4", "type": "synonym", "evidence": [ { "id": "A0A8V1A441", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A441/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A441", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A441" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PPFIA4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A441", "locus": { "chromosome": "26", "start_pos": 1014746, "end_pos": 990597, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010025188", "url": "https://www.ensembl.org/id/ENSGALG00010025188" } ] } } ], "crossref": [ { "id": "A0A8V1A441", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A441", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd09562", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09562", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd09565", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09565", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd09568", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09568", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001660", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001660", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013761", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013761", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029515", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029515", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037620", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037620", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037621", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037621", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037622", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037622", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057892", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057892", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A441", "url": "https://www.orthodb.org/?gene=A0A8V1A441", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A6E5", "url": "https://www.orthodb.org/?gene=A0A8V1A6E5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A9A8", "url": "https://www.orthodb.org/?gene=A0A8V1A9A8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A9B2", "url": "https://www.orthodb.org/?gene=A0A8V1A9B2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12587", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12587", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12587:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12587:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00536", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00536", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07647", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07647", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25526", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25526", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-181429", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-181429", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-181430", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-181430", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-212676", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-212676", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-264642", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-264642", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-388844", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-388844", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1A441", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A441", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A441-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A441-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A6E5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6E5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A6E5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6E5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A9A8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9A8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A9A8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9A8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A9B2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9B2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A9B2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9B2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMCEVMPTISEGDPLGPPQGSEADADFEQLMVNMLDERDKLLDTLRETRETLSVTQSRLQEALRERDQLQRQLNSALPQEFATLTRELSACREQLLEREEEISELKAERNNTRLLLEHLECLVSRHERSLRMTVVKRQAQSPSGVSSEVEVLKALKSLFEHHKALDEKVRERLRASLERVATLEEQLVDAHRQVAALQQGATREAPASERDEREPKEAAQKLPWKRLSNGSVHPEDEAGRVVELQELLEKQNFEVVQAKEHISALAASVAELEEDLGTARKDLIKSEEMSSKYQRDLREALAQKEDMEERITTLEKRYLAAQREATSIHDLNDKLESELANKESLHRQAPRGTSWCVTQCEEKARHLQELLELAEQKLQQTMRKAETLPEVEAELAQRIAALTKAKERHGSIEEHLRQLESQLEEKNQELARARQREKMNEEHNKRLSDTVDRLLSESNERLQLHLKERMAALEEKNTLLQELENTQKQIEEHQHDKRRLSDEIDKLRLEVDQLKTRSGTFVESVHTRSHMGSATDLRFPLSAVVHAPAEPFGTAPGLPRTQKGRFATRREETAKDWEQAQAGSVHAFDSDPEISDVDEDDRETLFSSMDVLSPGGHSDAQTLAMMLQEQLDAINEEIRMIQEEKESTELRAEELETRVTSGSMEGLNLTQLCKRASIPTSLTALSLASSSPPLSGRSTPKLTSRSAAQDLDRMGIMTLPSDLRKHRRKLLSPAARDESREDKTTIKCETSPPSSPRTLRLEKLGHPALSQEDGKSSLEEQASNPSSNSSQDSLHKGSKRKGIKSSIGRLFGKKEKGRLIQLSREGATGQVLLTDTEVGIQDPLGLGKLGAQAEKDRRLRKKHELLEEARRKGLPFAHWDGPTVVSWLELWVGMPAWYVAACRANVKSGAIMSALSDTEIQREIGISNALHRLKLRLAIQEMVSLTSPSAPPTSRTSSGNVWVTHEEMENMATSTKTDTEEGSWAQTLAYGDMNHEWIGNEWLPSLGLPQYRSYFMECLVDARMLDHLTKKDLRVHLKMVDSFHRTSLQYGIMCLKRLNYDRKELERRREETQHEIKDVLVWTNDQVIHWIQSIGLREYANNLVESGVHGALLALDENFDHNSLALVLQIPTQNTQARQVLEREFNNLLALGTDRRLDDGDDKTFRRTPSWRKRFRPRDMHSINMLSGSAETLPAGFRVTSLVPLPPPSAPAKKMPPEVGASGSPRLETSTVRTYSC", "length": 1237, "header": "tr|A0A8V1A441-1|A0A8V1A441_CHICK Isoform 1 of PTPRF interacting protein alpha 4 OS=Gallus gallus OX=9031 GN=PPFIA4 PE=3 SV=1 CANONICAL=A0A8V1A441-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A441-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A441/entry#A0A8V1A441-1", "sequence": { "sequence": "MMCEVMPTISEGDPLGPPQGSEADADFEQLMVNMLDERDKLLDTLRETRETLSVTQSRLQEALRERDQLQRQLNSALPQEFATLTRELSACREQLLEREEEISELKAERNNTRLLLEHLECLVSRHERSLRMTVVKRQAQSPSGVSSEVEVLKALKSLFEHHKALDEKVRERLRASLERVATLEEQLVDAHRQVAALQQGATREAPASERDEREPKEAAQKLPWKRLSNGSVHPEDEAGRVVELQELLEKQNFEVVQAKEHISALAASVAELEEDLGTARKDLIKSEEMSSKYQRDLREALAQKEDMEERITTLEKRYLAAQREATSIHDLNDKLESELANKESLHRQAPRGTSWCVTQCEEKARHLQELLELAEQKLQQTMRKAETLPEVEAELAQRIAALTKAKERHGSIEEHLRQLESQLEEKNQELARARQREKMNEEHNKRLSDTVDRLLSESNERLQLHLKERMAALEEKNTLLQELENTQKQIEEHQHDKRRLSDEIDKLRLEVDQLKTRSGTFVESVHTRSHMGSATDLRFPLSAVVHAPAEPFGTAPGLPRTQKGRFATRREETAKDWEQAQAGSVHAFDSDPEISDVDEDDRETLFSSMDVLSPGGHSDAQTLAMMLQEQLDAINEEIRMIQEEKESTELRAEELETRVTSGSMEGLNLTQLCKRASIPTSLTALSLASSSPPLSGRSTPKLTSRSAAQDLDRMGIMTLPSDLRKHRRKLLSPAARDESREDKTTIKCETSPPSSPRTLRLEKLGHPALSQEDGKSSLEEQASNPSSNSSQDSLHKGSKRKGIKSSIGRLFGKKEKGRLIQLSREGATGQVLLTDTEVGIQDPLGLGKLGAQAEKDRRLRKKHELLEEARRKGLPFAHWDGPTVVSWLELWVGMPAWYVAACRANVKSGAIMSALSDTEIQREIGISNALHRLKLRLAIQEMVSLTSPSAPPTSRTSSGNVWVTHEEMENMATSTKTDTEEGSWAQTLAYGDMNHEWIGNEWLPSLGLPQYRSYFMECLVDARMLDHLTKKDLRVHLKMVDSFHRTSLQYGIMCLKRLNYDRKELERRREETQHEIKDVLVWTNDQVIHWIQSIGLREYANNLVESGVHGALLALDENFDHNSLALVLQIPTQNTQARQVLEREFNNLLALGTDRRLDDGDDKTFRRTPSWRKRFRPRDMHSINMLSGSAETLPAGFRVTSLVPLPPPSAPAKKMPPEVGASGSPRLETSTVRTYSC", "length": 1237, "header": "tr|A0A8V1A441-1|A0A8V1A441_CHICK Isoform 1 of PTPRF interacting protein alpha 4 OS=Gallus gallus OX=9031 GN=PPFIA4 PE=3 SV=1 CANONICAL=A0A8V1A441-1" }, "locus": { "chromosome": "26", "start_pos": 1013383, "end_pos": 990796, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010061451.1", "url": "https://www.ensembl.org/id/ENSGALT00010061451.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010037970.1", "url": "https://www.ensembl.org/id/ENSGALP00010037970.1" } ] } }, { "isoform_ac": "A0A8V1A6E5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A441/entry#A0A8V1A6E5-1", "sequence": { "sequence": "MMCEVMPTISEGDPLGPPQGSEADADFEQLMVNMLDERDKLLDTLRETRETLSVTQSRLQEALRERDQLQRQLNSALPQEFATLTRELSACREQLLEREEEISELKAERNNTRLLLEHLECLVSRHERSLRMTVVKRQAQSPSGVSSEVEVLKALKSLFEHHKALDEKVRERLRASLERVATLEEQLVDAHRQVAALQQGATREAPASERDEREPKEAAQKLPWKRLSNGSVHPEDEAGRVVELQELLEKQNFEVVQAKEHISALAASVAELEEDLGTARKDLIKSEEMSSKYQRDLREALAQKEDMEERITTLEKRYLAAQREATSIHDLNDKLESELANKESLHRQCEEKARHLQELLELAEQKLQQTMRKAETLPEVEAELAQRIAALTKAKERHGSIEEHLRQLESQLEEKNQELARARQREKMNEEHNKRLSDTVDRLLSESNERLQLHLKERMAALEEKNTLLQELENTQKQIEEHQHDKRRLSDEIDKLRLEVDQLKTRSGTFVESVHTRSHMGSATDLRFPLSAVVHAPAEPFGTAPGLPRTQKGRFATRREETAKDWEQAQAGSVHAFDSDPEISDVDEDDRETLFSSMDVLSPGGHSDAQTLAMMLQEQLDAINEEIRMIQEEKESTELRAEELETRVTSGSMEGLNLTQLCKRASIPTSLTALSLASSSPPLSGRSTPKLTSRSAAQDLDRMGIMTLSPAARDESREDKTTIKCETSPPSSPRTLRLEKLGHPALSQEDGKSSLEEQASNPSSNSSQDSLHKGSKRKGIKSSIGRLFGKKEKGRLIQLSREGATGQVLLTDTEVGIQDPLGLGKLGAQAEKDRRLRKKHELLEEARRKGLPFAHWDGPTVVSWLELWVGMPAWYVAACRANVKSGAIMSALSDTEIQREIGISNALHRLKLRLAIQEMVSLTSPSAPPTSRTSSGNVWVTHEEMENMATSTKTDTEEGSWAQTLAYGDMNHEWIGNEWLPSLGLPQYRSYFMECLVDARMLDHLTKKDLRVHLKMVDSFHRTSLQYGIMCLKRLNYDRKELERRREETQHEIKDVLVWTNDQVIHWIQSIGLREYANNLVESGVHGALLALDENFDHNSLALVLQIPTQNTQARQVLEREFNNLLALGTDRRLDDGDDKTFRRTPSWRKRFRPRDMHSINMLSGSAETLPAGFRVTSLVPLPPPSAPAKKMPPEVGASGSPRLETSTVRTYSC", "length": 1214, "header": "tr|A0A8V1A6E5-1|A0A8V1A6E5_CHICK Computationally mapped isoform of PTPRF interacting protein alpha 4 OS=Gallus gallus OX=9031 GN=PPFIA4 PE=3 SV=1 CANONICAL=A0A8V1A441-1" }, "locus": { "chromosome": "26", "start_pos": 1013383, "end_pos": 990796, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010061466.1", "url": "https://www.ensembl.org/id/ENSGALT00010061466.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010037975.1", "url": "https://www.ensembl.org/id/ENSGALP00010037975.1" } ] } }, { "isoform_ac": "A0A8V1A9A8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A441/entry#A0A8V1A9A8-1", "sequence": { "sequence": "MMCEVMPTISEGDPLGPPQGSEADADFEQLMVNMLDERDKLLDTLRETRETLSVTQSRLQEALRERDQLQRQLNSALPQEFATLTRELSACREQLLEREEEISELKAERNNTRLLLEHLECLVSRHERSLRMTVVKRQAQSPSGVSSEVEVLKALKSLFEHHKALDEKVRERLRASLERVATLEEQLVDAHRQVAALQQGATREAPASERDEREPKEAAQKLPWKRLSNGSVHPEDEAGRVVELQELLEKQNFEVVQAKEHISALAASVAELEEDLGTARKDLIKSEEMSSKYQRDLREALAQKEDMEERITTLEKRYLAAQREATSIHDLNDKLESELANKESLHRQCEEKARHLQELLELAEQKLQQTMRKAETLPEVEAELAQRIAALTKAKERHGSIEEHLRQLESQLEEKNQELARARQREKMNEEHNKRLSDTVDRLLSESNERLQLHLKERMAALEEKNTLLQELENTQKQIEEHQHDKRRLSDEIDKLRLEVDQLKTRSGTFVESVHTRSHMGSATDLRFPLSAVVHAPAEPFGTAPGLPRTQKGRFATRREETAKDWEQAQAGSVHAFDSDPEISDVDEDDRETLFSSMDVLSPGGHSDAQTLAMMLQEQLDAINEEIRMIQEEKESTELRAEELETRVTSGSMEGLNLTQLCKRASIPTSLTALSLASSSPPLSGRSTPKLTSRSAAQDLDRMGIMTLPSDLRKHRRKLLSPAARDESREDKTTIKCETSPPSSPRTLRLEKLGHPALSQEDGKSSLEEQASNPSSNSSQDSLHKGSKRKGIKSSIGRLFGKKEKGRLIQLSREGATGQVLLTDTEVGIQDPLGLGKLGAQAEKDRRLRKKHELLEEARRKGLPFAHWDGPTVVSWLELWVGMPAWYVAACRANVKSGAIMSALSDTEIQREIGISNALHRLKLRLAIQEMVSLTSPSAPPTSRTSSGNVWVTHEEMENMATSTKTTLAYGDMNHEWIGNEWLPSLGLPQYRSYFMECLVDARMLDHLTKKDLRVHLKMVDSFHRTSLQYGIMCLKRLNYDRKELERRREETQHEIKDVLVWTNDQVIHWIQSIGLREYANNLVESGVHGALLALDENFDHNSLALVLQIPTQNTQARQVLEREFNNLLALGTDRRLDDGDDKTFRRTPSWRKRFRPRDMHSINMLSGSAETLPAGFRVTSLVPLPPPSAPAKKMPPEVGASGSPRLETSTVRTYSC", "length": 1217, "header": "tr|A0A8V1A9A8-1|A0A8V1A9A8_CHICK Computationally mapped isoform of PTPRF interacting protein alpha 4 OS=Gallus gallus OX=9031 GN=PPFIA4 PE=3 SV=1 CANONICAL=A0A8V1A441-1" }, "locus": { "chromosome": "26", "start_pos": 1013383, "end_pos": 990796, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010061458.1", "url": "https://www.ensembl.org/id/ENSGALT00010061458.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010037972.1", "url": "https://www.ensembl.org/id/ENSGALP00010037972.1" } ] } }, { "isoform_ac": "A0A8V1A9B2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A441/entry#A0A8V1A9B2-1", "sequence": { "sequence": "MMCEVMPTISEGDPLGPPQGSEADADFEQLMVNMLDERDKLLDTLRETRETLSVTQSRLQEALRERDQLQRQLNSALPQEFATLTRELSACREQLLEREEEISELKAERNNTRLLLEHLECLVSRHERSLRMTVVKRQAQSPSGVSSEVEVLKALKSLFEHHKALDEKVRERLRASLERVATLEEQLVDAHRQVAALQQGATREAPASERDEREPKEAAQKLPWKRLSNGSVHPEDEAGRVVELQELLEKQNFEVVQAKEHISALAASVAELEEDLGTARKDLIKSEEMSSKYQRDLREALAQKEDMEERITTLEKRYLAAQREATSIHDLNDKLESELANKESLHRQCEEKARHLQELLELAEQKLQQTMRKAETLPEVEAELAQRIAALTKAKERHGSIEEHLRQLESQLEEKNQELARARQREKMNEEHNKRLSDTVDRLLSESNERLQLHLKERMAALEEKRRLSDEIDKLRLEVDQLKTRSGTFVESVHTRSHMGSATDLRFPLSAVVHAPAEPFGTAPGLPRTQKGRFATRREETAKDWEQAQAGSVHAFDSDPEISDVDEDDRETLFSSMDVLSPGGHSDAQTLAMMLQEQLDAINEEIRMIQEEKESTELRAEELETRVTSGSMEGLNLTQLCKRASIPTSLTALSLASSSPPLSGRSTPKLTSRSAAQDLDRMGIMTLPSDLRKHRRKLLSPAARDESREDKTTIKCETSPPSSPRTLRLEKLGHPALSQEDGKSSLEEQASNPSSNSSQDSLHKGSKRKGIKSSIGRLFGKKEKGRLIQLSREGATGQVLLTDTEVGIQDPLGLGKLGAQAEKDRRLRKKHELLEEARRKGLPFAHWDGPTVVSWLELWVGMPAWYVAACRANVKSGAIMSALSDTEIQREIGISNALHRLKLRLAIQEMVSLTSPSAPPTSRTSSGNVWVTHEEMENMATSTKTDTEEGSWAQTLAYGDMNHEWIGNEWLPSLGLPQYRSYFMECLVDARMLDHLTKKDLRVHLKMVDSFHRTSLQYGIMCLKRLNYDRKELERRREETQHEIKDVLVWTNDQVIHWIQSIGLREYANNLVESGVHGALLALDENFDHNSLALVLQIPTQNTQARQVLEREFNNLLALGTDRRLDDGDDKTFRRTPSWRKRFRPRDMHSINMLSGSAETLPAGFRVTSLVPLPPPSAPAKKMPPEVGASGSPRLETSTVRTYSC", "length": 1205, "header": "tr|A0A8V1A9B2-1|A0A8V1A9B2_CHICK Computationally mapped isoform of PTPRF interacting protein alpha 4 OS=Gallus gallus OX=9031 GN=PPFIA4 PE=3 SV=1 CANONICAL=A0A8V1A441-1" }, "locus": { "chromosome": "26", "start_pos": 1013383, "end_pos": 990796, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010061477.1", "url": "https://www.ensembl.org/id/ENSGALT00010061477.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010037978.1", "url": "https://www.ensembl.org/id/ENSGALP00010037978.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-181429", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-181429", "resource": "Reactome", "description": "Serotonin Neurotransmitter Release Cycle" }, { "id": "R-GGA-181430", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-181430", "resource": "Reactome", "description": "Norepinephrine Neurotransmitter Release Cycle" }, { "id": "R-GGA-212676", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-212676", "resource": "Reactome", "description": "Dopamine Neurotransmitter Release Cycle" }, { "id": "R-GGA-264642", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-264642", "resource": "Reactome", "description": "Acetylcholine Neurotransmitter Release Cycle" }, { "id": "R-GGA-388844", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-388844", "resource": "Reactome", "description": "Receptor-type tyrosine-protein phosphatases" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A441", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A441" } ], "pmid": "" }, { "name": "presynaptic active zone", "id": "GO:0048786", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048786", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A441", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A441" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "synapse organization", "id": "GO:0050808", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050808", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A441", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A441" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 110, "end_pos": 112, "annotation": "n_glycosylation_sequon" }, { "start_pos": 229, "end_pos": 231, "annotation": "n_glycosylation_sequon" }, { "start_pos": 668, "end_pos": 670, "annotation": "n_glycosylation_sequon" }, { "start_pos": 788, "end_pos": 790, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1A441", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A441" }, { "id": "PS50105", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50105" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SAM", "eco_id": "ECO_0000259", "start_pos": 879, "end_pos": 945, "start_aa": "Trp", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 110, "end_pos": 112 }, { "start_pos": 229, "end_pos": 231 }, { "start_pos": 668, "end_pos": 670 }, { "start_pos": 788, "end_pos": 790 } ] }, "class_list": [], "section_stats": [ { "table_id": 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}, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A450-1", "uniprot_ac": "A0A8V1A450", "uniprot_id": "A0A8V1A450_CHICK", "mass": { "chemical_mass": 44599.0, "monoisotopic_mass": 44599.0 }, "refseq": { "ac": "XP_417369", "name": "potassium channel subfamily K member 15", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417369" }, "gene_names": [ { "name": "KCNK15", "type": "recommended", "evidence": [ { "id": "A0A8V1A450", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A450" } ] }, { "name": "KCNK15", "type": "synonym", "evidence": [ { "id": "XP_417369", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417369" } ] } ], "protein_names": [ { "name": "Potassium two pore domain channel subfamily K member 15", "type": "synonym", "evidence": [ { "id": "A0A8V1A450", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A450/entry#names_and_taxonomy" } ] }, { "name": "potassium channel subfamily K member 15", "type": "synonym", "evidence": [ { "id": "XP_417369", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417369" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052551.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_417369.5. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_417369", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417369" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A450", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A450" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "KCNK15", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A450", "locus": {} } ], "crossref": [ { "id": "A0A8V1A450", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A450", "database": "AlphaFoldDB", "categories": [] }, { "id": "419191", "url": "https://www.ncbi.nlm.nih.gov/gene/419191", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003092", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003092", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003280", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003280", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008073", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008073", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013099", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013099", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:419191", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419191", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ERKRWEF", "url": "https://omabrowser.org/oma/group/ERKRWEF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A450", "url": "https://www.orthodb.org/?gene=A0A8V1A450", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11003", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11003", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11003:SF18", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11003:SF18", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07885", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07885", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-5576886", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5576886", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_417369", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417369", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1A450", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A450", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A450-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A450-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKRQNLRTAALILCIFSYLLVGAAVFDALESEAESGRKRLLEQKRGELRRKYRFSADDYRELERLVLQAEPHRAGRQWKFAGSFYFAITVITTIGYGHAAPGTDAGKVFCMFYAILGIPLTLVMFQSLGERMNTVVRLLLKKIKKCLGMRTTNVSMENMVLVGFLSCMGTLCIGAAAFSYFEGWTFFHAYYYCFITLTTIGFGDFVALQKNEALQKKPPYVAFSFMYILVGLTVIGAFLNLVVLRFLTMNSEDERRDAEERASLRRARNAIHLTAKEDGRSNKAIFLPAEDRTSQMNLIPLAQEDAERQRRQSANGAGKVPAFCTCLCYRAPLCGSPAPSHPETLSCHTNPVYYNSISYKIDEVSLSTRGQTGSSPASTLSSGSPRCPRHPRPRRKSI", "length": 398, "header": "tr|A0A8V1A450-1|A0A8V1A450_CHICK Isoform 1 of Potassium two pore domain channel subfamily K member 15 OS=Gallus gallus OX=9031 GN=KCNK15 PE=3 SV=1 CANONICAL=A0A8V1A450-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A450-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A450/entry#A0A8V1A450-1", "sequence": { "sequence": "MKRQNLRTAALILCIFSYLLVGAAVFDALESEAESGRKRLLEQKRGELRRKYRFSADDYRELERLVLQAEPHRAGRQWKFAGSFYFAITVITTIGYGHAAPGTDAGKVFCMFYAILGIPLTLVMFQSLGERMNTVVRLLLKKIKKCLGMRTTNVSMENMVLVGFLSCMGTLCIGAAAFSYFEGWTFFHAYYYCFITLTTIGFGDFVALQKNEALQKKPPYVAFSFMYILVGLTVIGAFLNLVVLRFLTMNSEDERRDAEERASLRRARNAIHLTAKEDGRSNKAIFLPAEDRTSQMNLIPLAQEDAERQRRQSANGAGKVPAFCTCLCYRAPLCGSPAPSHPETLSCHTNPVYYNSISYKIDEVSLSTRGQTGSSPASTLSSGSPRCPRHPRPRRKSI", "length": 398, "header": "tr|A0A8V1A450-1|A0A8V1A450_CHICK Isoform 1 of Potassium two pore domain channel subfamily K member 15 OS=Gallus gallus OX=9031 GN=KCNK15 PE=3 SV=1 CANONICAL=A0A8V1A450-1" }, "locus": { "chromosome": "20", "start_pos": 5676646, "end_pos": 5673189, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010059097.1", "url": "https://www.ensembl.org/id/ENSGALT00010059097.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036056.1", "url": "https://www.ensembl.org/id/ENSGALP00010036056.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:419191", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419191", "resource": "KEGG Pathway" }, { "id": "R-GGA-5576886", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5576886", "resource": "Reactome", "description": "Phase 4 - resting membrane potential" } ], "orthologs": [ { "uniprot_canonical_ac": "E1BEH3-1", "protein_name": "Potassium two pore domain channel subfamily K member 15", "gene_name": "KCNK15", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRKQSARTAALVLCILSYLLVGAAVFDALESEAESGRKRLLAQKRSELRRKYGFSAEDYRELERLALQAEPHRAGRQWKFAGSFYFAITVITTIGYGHAAPGTDSGKVFCMFYALLGIPLTLVTFQSLGERLNALVRRLLLAAKRCLGLRRPRVSPENMAVAGLLVCAGTLALGAAAFAHFEGWTFFHAYYYCFITLTTIGFGDFVALQNDEALQRKPPYVAFSFLYMLLGLTVIGAFLNLVVLRFLAAGADAPERAARPLRRGAPENRGPARRAGLISVSCRLHRLELCSRDNPGFSPPASPGAAGGGRADRPPARRKSI", "length": 321 }, "evidence": [ { "id": "A0A8V1A450", "url": "https://omabrowser.org/oma/group/A0A8V1A450/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1Q5K8-1", "protein_name": "Potassium channel subfamily K member", "gene_name": "kcnk15", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MKKQNVRTLSLILCIFSYLLVGAAVFVALESDTESARKRMLEHKRAELRRKYRFTDGDYQELERVLRQAEPHRAGTQWRFAGSFYFAITVITTIGYGHAAPGTDAGKLFCMLYAGLGIPLTLVMFQSLGERMNTGVRFLLSRMKRALGLQRTEISTQNMVLVGVLSCLGTLCVGAAAFSHFESWTFFHAYYYCFITLTTIGFGDFVALQKKEDLQENQPYVLFSFIYILLGLTVIGAFLNLVVLRFLTLNTEDEKRDAAERASQRASLRASSLRKAPAFRRDSQTHSRTNLLSPRPTPHLRWFCSRVHLDHTSACRNTCAGCSVSSVSCRIHADTAFSSPRSTLSAGLSFTTRRKSL", "length": 357 }, "evidence": [ { "id": "A0A8V1A450", "url": "https://omabrowser.org/oma/group/A0A8V1A450/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8R5I0-1", "protein_name": "Potassium channel subfamily K member 15", "gene_name": "Kcnk15", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRKQSARTAALILCILSYLLVGAAVFDALESEAERSRQRLLARKRGEFRRKYRFSADDYRELERLALQAEPHRAGRQWRFAGSFYFAITVITTIGYGHAAPGTDSGKVFCMFYALLGIPLTLVTFQSLGERLNALVRCLLLAAKRCLGLRRPHVSAENMVVAGLLLCAATLALGAAAFAHFEGWTFFHAYYYCFITLTTIGFGDFVALQRDEALQKKPPYVAFSFLYILLGLTVIGAFLNLVVLRFLASAEAPERAALRRASVFRRGAPESRVRIPYPFHPLETWARDNPAFSPPLSPEAVHDCHSSPDRLRARRKSI", "length": 318 }, "evidence": [ { "id": "A0A8V1A450", "url": "https://omabrowser.org/oma/group/A0A8V1A450/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9H427-1", "protein_name": "Potassium channel subfamily K member 15", "gene_name": "KCNK15", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRRPSVRAAGLVLCTLCYLLVGAAVFDALESEAESGRQRLLVQKRGALRRKFGFSAEDYRELERLALQAEPHRAGRQWKFPGSFYFAITVITTIEYGHAAPGTDSGKVFCMFYALLGIPLTLVTFQSLGERLNAVVRRLLLAAKCCLGLRWTCVSTENLVVAGLLACAATLALGAVAFSHFEGWTFFHAYYYCFITLTTIGFGDFVALQSGEALQRKLPYVAFSFLYILLGLTVIGAFLNLVVLRFLVASADWPERAARTPSPRPPGAPESRGLWLPRRPARSVGSASVFCHVHKLERCARDNLGFSPPSSPGVVRGGQAPRLGARWKSI", "length": 330 }, "evidence": [ { "id": "A0A8V1A450", "url": "https://omabrowser.org/oma/group/A0A8V1A450/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VHE0-1", "protein_name": "TWIK-related acid-sensitive K[+] channel 7", "gene_name": "Task7", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MMKRQNVRTLSLVVCTFTYLLIGAAVFDSLESPTEAKRWEFLQTVKNNFVRKYNVTDEDFRVMEIVIIENKPHKAGPQWKFAGAFYFSTVVLAMIGYGHSTPVTIPGKAFCMGYAMVGIPLGLVMFQSIGERLNKFASVIIRRAKRASGARCTDATEMNLMLATGMLSSIIITTGAAVFSRYEGWSYFDSFYYCFVTLTTIGFGDYVALQNDQALTNKPGYVALSLVFILFGLAVVAASINLLVLRFMTMQAEDAKRDEQDAQNLAGNAQPVTFDDESTYNMHGKLLENNYTTENDETASLCSCTCMGGTRCLNHEQFVDPDFQPTDIIESTLCLKRASV", "length": 340 }, "evidence": [ { "id": "A0A8V1A450", "url": "https://omabrowser.org/oma/group/A0A8V1A450/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "potassium ion leak channel activity", "id": "GO:0022841", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022841", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A450", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A450" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A450", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A450" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "potassium ion transmembrane transport", "id": "GO:0071805", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071805", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A450", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A450" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 153, "end_pos": 155, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1A450", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A450" }, { "id": "PF07885", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07885" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Potassium channel", "eco_id": "ECO_0000259", "start_pos": 76, "end_pos": 132, "start_aa": "Arg", "end_aa": "Met", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 153, "end_pos": 155 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A6H5-1", "uniprot_ac": "A0A8V1A6H5", "uniprot_id": "A0A8V1A6H5_CHICK", "mass": { "chemical_mass": 64525.0, "monoisotopic_mass": 64525.0 }, "refseq": {}, "gene_names": [ { "name": "SH2B3", "type": "recommended", "evidence": [ { "id": "A0A8V1A6H5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6H5" } ] } ], "protein_names": [ { "name": "SH2B adapter protein 3", "type": "recommended", "evidence": [ { "id": "A0A8V1A6H5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6H5/entry#names_and_taxonomy" } ] }, { "name": "Lymphocyte adapter protein", "type": "synonym", "evidence": [ { "id": "A0A8V1A6H5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6H5/entry#names_and_taxonomy" } ] }, { "name": "Lymphocyte-specific adapter protein Lnk", "type": "synonym", "evidence": [ { "id": "A0A8V1A6H5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6H5/entry#names_and_taxonomy" } ] }, { "name": "Signal transduction protein Lnk", "type": "synonym", "evidence": [ { "id": "A0A8V1A6H5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6H5/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Links T-cell receptor activation signal to phospholipase C-gamma-1, GRB2 and phosphatidylinositol 3-kinase.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A6H5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6H5#function" }, { "database": "UniProtKB", "id": "ARBA00059956", "url": "https://www.uniprot.org/uniprotkb/ARBA00059956#function" }, { "database": "UniProtKB", "id": "A0A8V1A454", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A454#function" }, { "database": "UniProtKB", "id": "A0A8V1A6I0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6I0#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A6H5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6H5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SH2B3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6H5", "locus": { "chromosome": "15", "start_pos": 6137141, "end_pos": 6118970, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010025743", "url": "https://www.ensembl.org/id/ENSGALG00010025743" } ] } } ], "crossref": [ { "id": "A0A8V1A6H5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A6H5", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd01231", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01231", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "416876", "url": "https://www.ncbi.nlm.nih.gov/gene/416876", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000980", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000980", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015012", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015012", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030523", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030523", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036290", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036290", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036860", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036860", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A454", "url": "https://www.orthodb.org/?gene=A0A8V1A454", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A6H5", "url": "https://www.orthodb.org/?gene=A0A8V1A6H5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A6I0", "url": "https://www.orthodb.org/?gene=A0A8V1A6I0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10872", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10872", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10872:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10872:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00017", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00017", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00169", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00169", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08916", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08916", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-1433559", "url": 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"https://www.uniprot.org/uniprotkb/A0A8V1A6I0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRVAKWGGVGEGSILMAPLCSVLQHGHLAGATAMNGHALPAGTPAYPRGWHEFCELHAISTAKELARHYLRFATEHPHHDLLAAENFSLRFADLFQQYFCNEVKEGFAMSQLRILPAGPARDYRDTQRQHANPSLGTAASKGEAEPPARPEPPAEPPTGLRKSWSSEELTGPARRPFSLSQLRRSWRSLFRRRSSDALPTEADGEVAEAALKSGLSKRILPWGLSREQPLEVRKEGTLRYGLLDETSLDSGTRWQRCRLVLRRAGMPDGEEYVLELFDPPKGSKPKLRAACSAIQEVRRCTRLEMPDNLHTFVLKVTNATDVLFEAGDEQQLSSWMAEIRQCACRGSDVGDPELLSGRHPDPAATSPPTSSDSPSQGAMPGGPPEAAGPKMEQFLSSCPWFHGPISRVKAAQLVQLGGLEGHGVFLVRQSETRRGEYVLTFNFQGRAKHLRLSLTERGQCRVQHLRFSSITEMLHHFHRYPIPLECGATCDVRLSSYVVVLPQAPAPGSSPALPVPLPFWSPEFSLTPSESPPEPIFHLVPPVAELAQGSHPNGAPHGARPRDSDYEVEAPGRGRMRAVDNQYTPL", "length": 586, "header": "tr|A0A8V1A6H5-1|A0A8V1A6H5_CHICK Isoform 1 of SH2B adapter protein 3 OS=Gallus gallus OX=9031 GN=SH2B3 PE=3 SV=1 CANONICAL=A0A8V1A6H5-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A454-1", "url": 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"recommended", "evidence": [ { "id": "A0A8V1A472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A472" } ] }, { "name": "TPM3", "type": "synonym", "evidence": [ { "id": "NP_001384372", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384372" } ] } ], "protein_names": [ { "name": "Tropomyosin 3", "type": "synonym", "evidence": [ { "id": "A0A8V1A472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A472/entry#names_and_taxonomy" } ] }, { "name": "min alpha-trop", "type": "synonym", "evidence": [ { "id": "NP_001384372", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384372" } ] }, { "name": "tropomyosin alpha-3 chain isoform q", "type": "synonym", "evidence": [ { "id": "NP_001384372", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384372" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR13267659.254451.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992484, SAMEA103992639 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000351.1. On Nov 16, 2021 this sequence version replaced XP_015154071.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001384372", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384372" } ] }, { "annotation": "Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGH7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGH7#function" }, { "database": "UniProtKB", "id": "ARBA00037240", "url": "https://www.uniprot.org/uniprotkb/ARBA00037240#function" }, { "database": "UniProtKB", "id": "A0A8V1AGI2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGI2#function" }, { "database": "UniProtKB", "id": "A0A8V1A472", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A472#function" }, { "database": "UniProtKB", "id": "A0A8V1A477", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A477#function" }, { "database": "UniProtKB", "id": "A0A8V1A920", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A920#function" }, { "database": "UniProtKB", "id": "A0A8V1AEH6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEH6#function" }, { "database": "UniProtKB", "id": "A0A8V1ABT6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABT6#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A472", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A472" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TPM3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A472", "locus": { "chromosome": "25", "start_pos": 1874714, "end_pos": 1890861, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027391", "url": "https://www.ensembl.org/id/ENSGALG00010027391" } ] } } ], "crossref": [ { "id": "A0A8V1A472", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A472", "database": "AlphaFoldDB", "categories": [] }, { "id": "770103", "url": "https://www.ncbi.nlm.nih.gov/gene/770103", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000533", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000533", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014751", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014751", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A472", "url": "https://www.orthodb.org/?gene=A0A8V1A472", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A477", "url": "https://www.orthodb.org/?gene=A0A8V1A477", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A920", "url": "https://www.orthodb.org/?gene=A0A8V1A920", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A935", "url": "https://www.orthodb.org/?gene=A0A8V1A935", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ABS0", "url": "https://www.orthodb.org/?gene=A0A8V1ABS0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ABT6", "url": "https://www.orthodb.org/?gene=A0A8V1ABT6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AEH6", "url": "https://www.orthodb.org/?gene=A0A8V1AEH6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AGH7", "url": "https://www.orthodb.org/?gene=A0A8V1AGH7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AGI2", "url": "https://www.orthodb.org/?gene=A0A8V1AGI2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19269", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19269", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00261", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00261", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001384372", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384372", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1A472", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A472", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A472-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A472-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A477", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A477", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A477-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A477-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A920", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A920", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A920-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A920-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A935", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A935", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A935-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A935-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ABS0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABS0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ABS0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABS0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ABT6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABT6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ABT6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABT6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AEH6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEH6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AEH6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEH6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGH7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGH7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGH7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGH7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGI2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGI2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGI2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGI2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAGATTIEAVKRKIQVLQQQADDAEERADRLQREVEAERRNREQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESRVRELQEQIRVMDQNLKCLSVAEEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEERLYSQLEKNRLLSNELKLTLHDLCD", "length": 247, "header": "tr|A0A8V1A472-1|A0A8V1A472_CHICK Isoform 1 of Tropomyosin 3 OS=Gallus gallus OX=9031 GN=TPM3 PE=1 SV=1 CANONICAL=A0A8V1A472-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A472-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A472/entry#A0A8V1A472-1", "sequence": { "sequence": "MAGATTIEAVKRKIQVLQQQADDAEERADRLQREVEAERRNREQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESRVRELQEQIRVMDQNLKCLSVAEEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEERLYSQLEKNRLLSNELKLTLHDLCD", "length": 247, "header": "tr|A0A8V1A472-1|A0A8V1A472_CHICK Isoform 1 of Tropomyosin 3 OS=Gallus gallus OX=9031 GN=TPM3 PE=1 SV=1 CANONICAL=A0A8V1A472-1" }, "locus": { "chromosome": "25", "start_pos": 1888753, "end_pos": 1877236, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066416.1", "url": "https://www.ensembl.org/id/ENSGALT00010066416.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040682.1", "url": "https://www.ensembl.org/id/ENSGALP00010040682.1" } ] } }, { "isoform_ac": "A0A8V1A477-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A472/entry#A0A8V1A477-1", "sequence": { "sequence": "MAGATTIEAVKRKIQVLQQQADDAEERADRLQREVEAERRNREQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESRVRELQEQIRVMDQNLKCLSVAEEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDELYAQKLKYKAISEELDHALNDMTSMARRALQESSFGEMGHLPWFPEPQIN", "length": 273, "header": "tr|A0A8V1A477-1|A0A8V1A477_CHICK Computationally mapped isoform of Tropomyosin 3 OS=Gallus gallus OX=9031 GN=TPM3 PE=1 SV=1 CANONICAL=A0A8V1A472-1" }, "locus": { "chromosome": "25", "start_pos": 1888753, "end_pos": 1875734, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066421.1", "url": "https://www.ensembl.org/id/ENSGALT00010066421.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040687.1", "url": "https://www.ensembl.org/id/ENSGALP00010040687.1" } ] } }, { "isoform_ac": "A0A8V1A920-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A472/entry#A0A8V1A920-1", "sequence": { "sequence": "MAGATTIEAVKRKIQVLQQQADDAEERADRLQREVEAERRNREQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESRVRELQEQIRVMDQNLKCLSVAEEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDELYAQKLKYKAISEELDHALNDMTSIPYH", "length": 251, "header": "tr|A0A8V1A920-1|A0A8V1A920_CHICK Computationally mapped isoform of Tropomyosin 3 OS=Gallus gallus OX=9031 GN=TPM3 PE=1 SV=1 CANONICAL=A0A8V1A472-1" }, "locus": { "chromosome": "25", "start_pos": 1888753, "end_pos": 1880686, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066408.1", "url": "https://www.ensembl.org/id/ENSGALT00010066408.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040674.1", "url": "https://www.ensembl.org/id/ENSGALP00010040674.1" } ] } }, { "isoform_ac": "A0A8V1A935-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A472/entry#A0A8V1A935-1", "sequence": { "sequence": "MEAIKKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKYSEALKDAQEKLELAEKKAADAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDKLKSTKEEHLCTQRMLDQTLLDLNEM", "length": 284, "header": "tr|A0A8V1A935-1|A0A8V1A935_CHICK Computationally mapped isoform of Tropomyosin 3 OS=Gallus gallus OX=9031 GN=TPM3 PE=1 SV=1 CANONICAL=A0A8V1A472-1" }, "locus": { "chromosome": "25", "start_pos": 1890723, "end_pos": 1875660, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066423.1", "url": "https://www.ensembl.org/id/ENSGALT00010066423.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040689.1", "url": "https://www.ensembl.org/id/ENSGALP00010040689.1" } ] } }, { "isoform_ac": "A0A8V1ABS0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A472/entry#A0A8V1ABS0-1", "sequence": { "sequence": "MAGATTIEAVKRKIQVLQQQADDAEERADRLQREVEAERRNREQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESRVRELQEQIRVMDQNLKCLSVAEEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDKSCDSKLHFGFTFLLGGLFCICTLHSCSRHLALNSSTFFHLRCTGHPWE", "length": 271, "header": "tr|A0A8V1ABS0-1|A0A8V1ABS0_CHICK Computationally mapped isoform of Tropomyosin 3 OS=Gallus gallus OX=9031 GN=TPM3 PE=1 SV=1 CANONICAL=A0A8V1A472-1" }, "locus": { "chromosome": "25", "start_pos": 1888753, "end_pos": 1880404, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066405.1", "url": "https://www.ensembl.org/id/ENSGALT00010066405.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040671.1", "url": "https://www.ensembl.org/id/ENSGALP00010040671.1" } ] } }, { "isoform_ac": "A0A8V1ABT6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A472/entry#A0A8V1ABT6-1", "sequence": { "sequence": "MAGATTIEAVKRKIQVLQQQADDAEERADRLQREVEAERRNREQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESRVRELQEQIRVMDQNLKCLSVAEEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDELYAQKLKYKAISEELDHALNDMTSMARRALQESSFGEMGHLPWFPEPQRVYPVSGRVDFFSGMGGLTYGLKRT", "length": 296, "header": "tr|A0A8V1ABT6-1|A0A8V1ABT6_CHICK Computationally mapped isoform of Tropomyosin 3 OS=Gallus gallus OX=9031 GN=TPM3 PE=1 SV=1 CANONICAL=A0A8V1A472-1" }, "locus": { "chromosome": "25", "start_pos": 1888753, "end_pos": 1876334, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066420.1", "url": "https://www.ensembl.org/id/ENSGALT00010066420.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040686.1", "url": "https://www.ensembl.org/id/ENSGALP00010040686.1" } ] } }, { "isoform_ac": "A0A8V1AEH6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A472/entry#A0A8V1AEH6-1", "sequence": { "sequence": "MAGATTIEAVKRKIQVLQQQADDAEERADRLQREVEAERRNREQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESRVRELQEQIRVMDQNLKCLSVAEEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDELYAQKLKYKAISEELDHALNDMTSIVSTRCLDVWISSVVWVGSPMD", "length": 269, "header": "tr|A0A8V1AEH6-1|A0A8V1AEH6_CHICK Computationally mapped isoform of Tropomyosin 3 OS=Gallus gallus OX=9031 GN=TPM3 PE=1 SV=1 CANONICAL=A0A8V1A472-1" }, "locus": { "chromosome": "25", "start_pos": 1888753, "end_pos": 1876345, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066419.1", "url": "https://www.ensembl.org/id/ENSGALT00010066419.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040685.1", "url": "https://www.ensembl.org/id/ENSGALP00010040685.1" } ] } }, { "isoform_ac": "A0A8V1AGH7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A472/entry#A0A8V1AGH7-1", "sequence": { "sequence": "MEAIKKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKYSEALKDAQEKLELAEKKAADAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKVGLLFPRARNAETRAEFAERSVAKLEKTIDDLEDELYAQKLKYKAISEELDHALNDMTSM", "length": 273, "header": "tr|A0A8V1AGH7-1|A0A8V1A472_CHICK Computationally mapped isoform of Tropomyosin 3 OS=Gallus gallus OX=9031 GN=TPM3 PE=1 SV=1 CANONICAL=A0A8V1A472-1" }, "locus": { "chromosome": "25", "start_pos": 1890723, "end_pos": 1881210, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066412.1", "url": "https://www.ensembl.org/id/ENSGALT00010066412.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040678.1", "url": "https://www.ensembl.org/id/ENSGALP00010040678.1" } ] } }, { "isoform_ac": "A0A8V1AGI2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A472/entry#A0A8V1AGI2-1", "sequence": { "sequence": "MAGATTIEAVKRKIQVLQQQADDAEERADRLQREVEAERRNREQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDELYAQKLKYKAISEELDHALNDMTSMARRALQESSFGEMGHLPWFPEPQRVYPVSGRVDFFSGMGGLTYGLKRT", "length": 296, "header": "tr|A0A8V1AGI2-1|A0A8V1A472_CHICK Computationally mapped isoform of Tropomyosin 3 OS=Gallus gallus OX=9031 GN=TPM3 PE=1 SV=1 CANONICAL=A0A8V1A472-1" }, "locus": { "chromosome": "25", "start_pos": 1888753, "end_pos": 1876334, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066417.1", "url": "https://www.ensembl.org/id/ENSGALT00010066417.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040683.1", "url": "https://www.ensembl.org/id/ENSGALP00010040683.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A472", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A472" } ], "pmid": "" }, { "name": "actin filament binding", "id": "GO:0051015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051015", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A472", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A472" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A472", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A472" } ], "pmid": "" }, { "name": "actin filament", "id": "GO:0005884", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005884", "evidence": [ { "database": "UniProtKB", "id": 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"A0A8V1A482", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A482", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR006694", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006694", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050307", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050307", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A482", "url": "https://www.orthodb.org/?gene=A0A8V1A482", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11863", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11863", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04116", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04116", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-6807047", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6807047", "database": "Reactome", 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"MDLVLEVADHHLLTPYVYPTGWPEDEPFRQLLSLFAITNLGALALYLLFGTLSYYFIFDHELKKHPQFLEVQREIIYALRSLPWISVPTVALFFAEVRGYSKLYDNIEDSPYGWPGVFLSMLSFLFFTDMGIYWIHRGLHHRLFYKRFHKPHHLWKIATPFASHAFHPVDGFMQSLPYHVYPFLFPLHKITYLGLYIFVNVWTISIHDGDYRVPRLLRHIINGSAHHTDHHLYFDYNYGQYFTLWDKIGGSYKSPTAFEGKGPHDYMRKLRENGSACPNGDTDKTK", "length": 286, "header": "tr|A0A8V1A482-1|A0A8V1A482_CHICK Isoform 1 of Sterol-C5-desaturase OS=Gallus gallus OX=9031 GN=SC5D PE=4 SV=1 CANONICAL=A0A8V1A482-1" }, "locus": { "chromosome": "24", "start_pos": 3589837, "end_pos": 3586667, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010062904.1", "url": "https://www.ensembl.org/id/ENSGALT00010062904.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038849.1", "url": "https://www.ensembl.org/id/ENSGALP00010038849.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-6807047", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6807047", "resource": "Reactome", "description": "Cholesterol biosynthesis via desmosterol (Bloch pathway)" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "C-5 sterol desaturase activity", "id": "GO:0000248", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000248", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A482", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A482" } ], "pmid": "" }, { "name": "iron ion binding", "id": "GO:0005506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005506", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A482", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A482" } ], "pmid": "" }, { "name": "delta7-sterol 5(6)-desaturase activity", "id": "GO:0050046", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050046", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A482", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A482" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A482", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A482" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A482", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A482" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "cholesterol biosynthetic process via desmosterol", "id": "GO:0033489", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033489", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A482", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A482" } ], "pmid": "" }, { "name": "cholesterol biosynthetic process via lathosterol", "id": "GO:0033490", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033490", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A482", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A482" } ], "pmid": "" }, { "name": "negative regulation of ferroptosis", "id": "GO:0110076", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0110076", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A482", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A482" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 222, "end_pos": 224, "annotation": "n_glycosylation_sequon" }, { "start_pos": 273, "end_pos": 275, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1A482", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A482" }, { "id": "PF04116", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04116" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Fatty acid hydroxylase", "eco_id": "ECO_0000259", "start_pos": 122, "end_pos": 250, "start_aa": "Leu", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 222, "end_pos": 224 }, { "start_pos": 273, "end_pos": 275 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": 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"total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A487-1", "uniprot_ac": "A0A8V1A487", "uniprot_id": "A0A8V1A487_CHICK", "mass": { "chemical_mass": 80842.0, "monoisotopic_mass": 80842.0 }, "refseq": { "ac": "XP_004942876", "name": "fidgetin isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004942876" }, "gene_names": [ { "name": "FIGN", "type": "recommended", "evidence": [ { "id": "A0A8V1A487", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A487" } ] }, { "name": "FIGN", "type": "synonym", "evidence": [ { "id": "XP_004942876", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004942876" } ] } ], "protein_names": [ { "name": "Fidgetin", "type": "recommended", "evidence": [ { "id": "A0A8V1A487", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A487/entry#names_and_taxonomy" } ] }, { "name": "fidgetin isoform X2", "type": "synonym", "evidence": [ { "id": "XP_004942876", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004942876" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052538.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004942876", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004942876" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A487", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A487" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FIGN", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A487", "locus": { "chromosome": "7", "start_pos": 20290619, "end_pos": 20110395, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010025791", "url": "https://www.ensembl.org/id/ENSGALG00010025791" } ] } } ], "crossref": [ { "id": "cd19523", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19523", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "429028", "url": "https://www.ncbi.nlm.nih.gov/gene/429028", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003593", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003593", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003959", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003959", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003960", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003960", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015415", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015415", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047828", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047828", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050304", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050304", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A487", "url": "https://www.orthodb.org/?gene=A0A8V1A487", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23074", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23074", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23074:SF14", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23074:SF14", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00004", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00004", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF09336", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09336", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004942876", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004942876", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1A487", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A487", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A487-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A487-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQWTPEHAQWPEQHFDITSTTRSPAHKVEAYRGHLQRTYQYAWANDDISALTASNLLKKYAEKYSGILEGPAERPILSNYTEAPSGLVNGRKNESEPWQPSLNSESVYPMNCVPDVITASKAGVSAALPPADVSASIGSSPGVASNLAEPSYSSSTCGSHTVPSLHSGLPSQEYAAGYNGSYLHTSYSGQPAPALPSPHPSPLHSSGLLQPPPPPPPPPALVPGYNGTSNLSSYSYPSATYPPQTAVGPGYSPGGAPPPSAYLPSGIPAPTPLPPTTVPSYSYQGHGLTPIAPSALTNSSASSLKRKAFYMAGQGEMDSSYGNYSYGQQRSTQSPMYRMPDNSISNANRGNGFDRSAETSSLAFKPTKQLMSSEQQRKFSSQSSRALTPPSYSTAKNSLGSRSSDSFGKYTSPVMNEHGDEHRQLLPHPMQGPGLRAATSSNHSVDEQLKNTDTHLIDLVTNEIINQGPPVDWNDIAGLDLVKAVIKEEVLWPVLRSDAFNGLTALPRSILLFGPRGTGKTLMGRCIASQLGATFFKITGSGLVTKWLGEGEKIVHASFLVARCRQPSVIFVSDIDMLLSSQVSEEHSPVSRMRTEFLMQLDTVLTSAEDQIVVICATSKPEEIDESLRRYFMKRLLIPLPDSTARHQIIVQLLSQHNYCLNDKEVALLVQRTEGFSGLDVAHLCQEAVVGPLHAMPATDLSAIMPSQLRPVTYQDFENAFCKIQPSISQKELDTYVEWNKMFGCSQ", "length": 747, "header": "tr|A0A8V1A487-1|A0A8V1A487_CHICK Isoform 1 of Fidgetin OS=Gallus gallus OX=9031 GN=FIGN PE=3 SV=1 CANONICAL=A0A8V1A487-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A487-1", "url": 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"locus": { "chromosome": "7", "start_pos": 20204120, "end_pos": 20201880, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010062898.1", "url": "https://www.ensembl.org/id/ENSGALT00010062898.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038845.1", "url": "https://www.ensembl.org/id/ENSGALP00010038845.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "microtubule severing ATPase activity", "id": "GO:0008568", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008568", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A487", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A487" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": 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[ { "database": "UniProtKB", "id": "A0A8V1A487", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A487" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 179, "end_pos": 181, "annotation": "n_glycosylation_sequon" }, { "start_pos": 226, "end_pos": 228, "annotation": "n_glycosylation_sequon" }, { "start_pos": 230, "end_pos": 232, "annotation": "n_glycosylation_sequon" }, { "start_pos": 298, "end_pos": 300, "annotation": "n_glycosylation_sequon" }, { "start_pos": 323, "end_pos": 325, "annotation": "n_glycosylation_sequon" }, { "start_pos": 442, "end_pos": 444, "annotation": "n_glycosylation_sequon" }, { "start_pos": 79, "end_pos": 81, "annotation": "n_glycosylation_sequon" }, { "start_pos": 93, "end_pos": 95, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1A487", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A487" }, { "id": "SM00382", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00382" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "AAA+ ATPase", "eco_id": "ECO_0000259", "start_pos": 506, "end_pos": 642, "start_aa": "Leu", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 179, "end_pos": 181 }, { "start_pos": 226, "end_pos": 228 }, { "start_pos": 230, "end_pos": 232 }, { "start_pos": 298, "end_pos": 300 }, { "start_pos": 323, "end_pos": 325 }, { "start_pos": 442, "end_pos": 444 }, { "start_pos": 79, "end_pos": 81 }, { "start_pos": 93, "end_pos": 95 } ] }, "class_list": [], 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"total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A4A4-1", "uniprot_ac": "A0A8V1A4A4", "uniprot_id": "A0A8V1A4A4_CHICK", "mass": { "chemical_mass": 237097.0, "monoisotopic_mass": 237097.0 }, "refseq": { "ac": "NP_990204", "name": "alpha-tectorin precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990204" }, "gene_names": [ { "name": "TECTA", "type": "recommended", "evidence": [ { "id": "A0A8V1A4A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4A4" } ] }, { "name": "TECTA", "type": "synonym", "evidence": [ { "id": "NP_990204", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990204" } ] } ], "protein_names": [ { "name": "Alpha-tectorin", "type": "recommended", "evidence": [ { "id": "A0A8V1A4A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4A4/entry#names_and_taxonomy" } ] }, { "name": "alpha-tectorin precursor", "type": "synonym", "evidence": [ { "id": "NP_990204", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990204" } ] }, { "name": "alpha-tectorin", "type": "synonym", "evidence": [ { "id": "NP_990204", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990204" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ012287.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN05341171 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000341.1. On Dec 3, 2021 this sequence version replaced NP_990204.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_990204", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990204" } ] }, { "annotation": "One of the major non-collagenous components of the tectorial membrane. The tectorial membrane is an extracellular matrix of the inner ear that covers the neuroepithelium of the cochlea and contacts the stereocilia bundles of specialized sensory hair cells. Sound induces movement of these hair cells relative to the tectorial membrane, deflects the stereocilia and leads to fluctuations in hair-cell membrane potential, transducing sound into electrical signals.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A4A4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4A4#function" }, { "database": "UniProtKB", "id": "ARBA00058814", "url": "https://www.uniprot.org/uniprotkb/ARBA00058814#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A4A4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4A4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TECTA", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4A4", "locus": { "chromosome": "24", "start_pos": 3591860, "end_pos": 3613880, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010025806", "url": "https://www.ensembl.org/id/ENSGALG00010025806" } ] } } ], "crossref": [ { "id": "cd19941", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19941", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "395686", "url": "https://www.ncbi.nlm.nih.gov/gene/395686", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001007", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001007", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001507", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001507", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001846", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001846", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002919", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002919", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003886", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003886", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014853", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014853", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017977", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017977", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025615", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025615", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036084", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036084", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042235", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042235", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052749", "url": 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"categories": [ "Protein Classification" ] }, { "id": "PF00094", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00094", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00100", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00100", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01826", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01826", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF06119", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06119", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08742", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08742", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12714", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12714", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_990204", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990204", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1A4A4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4A4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A4A4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4A4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNTRSLLSAWAALLVVTVRHRAHAMASLYPFWPNDTKTPKVDDGSSPEIKLSVPFIFFGAPYRTVYVNNNGVISFNSLVSQFTPEAFPLADGRAFVAPFWADVHNGIRGEIYYRESTNPELLGRASKDIRKYFKDMASFSASWVFIVTWEEVTFYGGSSTTPVNTFQAVLITDGVSSFAIFNYQEISWTTGTASGGDPLTGLGGVMAQAGFNGGNISNFFSIPGSRTPDIVNIEQTTNVNIPGRWAFKIDGREIDPANGCSLRGQFLHQGEIFWENSNCSTKCRCLDFNNEIFCQEMACGPFEACEPKIKFFQCVPVESSTCVVFGDPHYHTFDGFLFHFQGSCSYLLARQCWPGSQLPYFNVEAKNENRGGSSVSWLRDIFVEVYSHKIVLPKGGFGKAKVDDLVVSLPISLELGAIKVYQSGLSTALETDFGLLVTYDGQHYASVSVPGTYINGTCGLCGNYNKDPEDDALRSDGRLASSVPELGESWRVPHPERKCSPGCVENCSVCDASTESLYFSPEYCGFLNKSGGPLWECGSVVDPTAFVHSCVYDLCSARENGTGLCQAIQAYAAVCQGLGIPVGEWRAQTGCEAAVQCPEHSHYSVCASGCPATCSDLTAPLRCTAPCAEGCECDDGHVLSADRCIPVQKCGCDVDGRYYAVGEVFWATADCTAECQCEDGGEAKCFNTSCPEGEVCTIEDGYRGCYPKREGLCSVGQNQVLRTFDGVTFPYPLEHSYTLLKTCMEKPDFIEVDISQKKPGYAPNGLRVMRIQVVGQEVKVGGASLSEVKVNGYDVDLPYFHPSGHLEIYRTDNGTVTESEGLLSIGYYDSGLLEIRLSTAYFNCTGGLCGFFNGNDSDEFCTPKGKCTDNLELFLESWTTFDEICNGECGDLLKACNNDSELLKTYRSRSNCGIINDPTNSSFLECHNVVNVSAYYRTCLFRLCQSGGNQSELCDAVARYASACKNAEVDVGQWRSHSFCPLACPENSHFEECMSCVETCETLATGPVCMDTCTEGCQCDEGFALRGSHCVPRGECGCNFEGRQLATNQTFWMDISCHFLCYCNGSDNSVYCENVSCKDDEYCLEENGLYYCHVRTDASCIVSGYGHYLTFDGFSFDFQSSCALVLCTTISRPRAERSDTFPTFTVTAKNEDRDTSLALWVKQVEVEVFNYNIVIHRAYKYTVMINNERLYLPLKLGQGKVNIFAFGFHIVVETDFGLKVVYDWKTFLSVTIPRSFQNLTYGLCGRYNGNPDDDLVAAGGMPAFGVTDFVQSWAKRDTFCRVGCGDRCPACGKVEGFWKPQQLCSLIPSQSGVFAKCHSKINPSYFYKNCLFDTCVDGGAMQTACGWLQNYASTCQTQGIAIIGWRNFTSCSVSCPPNSHYESCVSLCQPRCAAIRLKSDCGHYCVEGCQCDPGYVLNGKSCILPQNCGCYSDGKYYEPKQLFWNGDCTRRCRCFRRNLIQCDPRHCKSDEECASRNGVRGCFSTRSSFCLAAGGGVFRTFDGAFLRFPANCAFVLSTICQKLPDFSFQLIINFDKWSSPNLTIISPVYFYINEEQILISDRSTVKVNGSLVSIPFVTGLSTKIYSQEGFLVIDSGPDIQIRYNGFNVIKITIGDRLQNKVCGLCGNFNGDPADDYATLRGKPVVSSVVLAQSWKTNGMQKSCNELQYSQYAASCDNVQIQKLQSDSYCLKLTDMKGFFQPCYGLLDPLPFYESCFLDGCYNRKQVQLCGSLAAYGEACRTFGILGTEWIEKENCSGVVEDPCAGADCPNRTCELDDGGELCGCIEPPPYGNTTHDIIDAEVTCKAAQMEVSISKCKLFQLGFEREGVRVNDRHCPGIEGEDFISFQINNTKGNCGNLVQSNSTHIVYKNTVWIESANNTGNIITRDRTINVEFSCAYELDIKISLDSVVRPMLSVINLTVPTQEGSFTTKMALYKNSSYKHPYRQGEVVLTTRDVLYVGVFVVGADSNHLILMLNKCYATPSRDSNDKLRYFIIEGGCQNLKDNTIGIEENGVSLTCRFHVTVFKFIGDYDEVHLHCAVSLCDSEKYSCKINCPQHRRSASAFAQEAHEQILSVGPIRRKRSDWCEDNGGCEQICTSQADGPLCSCVTGTLQGDGKSCRASSSSADSRAQASLLVVAQLWLWAALQDPTS", "length": 2151, "header": "tr|A0A8V1A4A4-1|A0A8V1A4A4_CHICK Isoform 1 of Alpha-tectorin OS=Gallus gallus OX=9031 GN=TECTA PE=4 SV=1 CANONICAL=A0A8V1A4A4-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A4A4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4A4/entry#A0A8V1A4A4-1", "sequence": { "sequence": "MNTRSLLSAWAALLVVTVRHRAHAMASLYPFWPNDTKTPKVDDGSSPEIKLSVPFIFFGAPYRTVYVNNNGVISFNSLVSQFTPEAFPLADGRAFVAPFWADVHNGIRGEIYYRESTNPELLGRASKDIRKYFKDMASFSASWVFIVTWEEVTFYGGSSTTPVNTFQAVLITDGVSSFAIFNYQEISWTTGTASGGDPLTGLGGVMAQAGFNGGNISNFFSIPGSRTPDIVNIEQTTNVNIPGRWAFKIDGREIDPANGCSLRGQFLHQGEIFWENSNCSTKCRCLDFNNEIFCQEMACGPFEACEPKIKFFQCVPVESSTCVVFGDPHYHTFDGFLFHFQGSCSYLLARQCWPGSQLPYFNVEAKNENRGGSSVSWLRDIFVEVYSHKIVLPKGGFGKAKVDDLVVSLPISLELGAIKVYQSGLSTALETDFGLLVTYDGQHYASVSVPGTYINGTCGLCGNYNKDPEDDALRSDGRLASSVPELGESWRVPHPERKCSPGCVENCSVCDASTESLYFSPEYCGFLNKSGGPLWECGSVVDPTAFVHSCVYDLCSARENGTGLCQAIQAYAAVCQGLGIPVGEWRAQTGCEAAVQCPEHSHYSVCASGCPATCSDLTAPLRCTAPCAEGCECDDGHVLSADRCIPVQKCGCDVDGRYYAVGEVFWATADCTAECQCEDGGEAKCFNTSCPEGEVCTIEDGYRGCYPKREGLCSVGQNQVLRTFDGVTFPYPLEHSYTLLKTCMEKPDFIEVDISQKKPGYAPNGLRVMRIQVVGQEVKVGGASLSEVKVNGYDVDLPYFHPSGHLEIYRTDNGTVTESEGLLSIGYYDSGLLEIRLSTAYFNCTGGLCGFFNGNDSDEFCTPKGKCTDNLELFLESWTTFDEICNGECGDLLKACNNDSELLKTYRSRSNCGIINDPTNSSFLECHNVVNVSAYYRTCLFRLCQSGGNQSELCDAVARYASACKNAEVDVGQWRSHSFCPLACPENSHFEECMSCVETCETLATGPVCMDTCTEGCQCDEGFALRGSHCVPRGECGCNFEGRQLATNQTFWMDISCHFLCYCNGSDNSVYCENVSCKDDEYCLEENGLYYCHVRTDASCIVSGYGHYLTFDGFSFDFQSSCALVLCTTISRPRAERSDTFPTFTVTAKNEDRDTSLALWVKQVEVEVFNYNIVIHRAYKYTVMINNERLYLPLKLGQGKVNIFAFGFHIVVETDFGLKVVYDWKTFLSVTIPRSFQNLTYGLCGRYNGNPDDDLVAAGGMPAFGVTDFVQSWAKRDTFCRVGCGDRCPACGKVEGFWKPQQLCSLIPSQSGVFAKCHSKINPSYFYKNCLFDTCVDGGAMQTACGWLQNYASTCQTQGIAIIGWRNFTSCSVSCPPNSHYESCVSLCQPRCAAIRLKSDCGHYCVEGCQCDPGYVLNGKSCILPQNCGCYSDGKYYEPKQLFWNGDCTRRCRCFRRNLIQCDPRHCKSDEECASRNGVRGCFSTRSSFCLAAGGGVFRTFDGAFLRFPANCAFVLSTICQKLPDFSFQLIINFDKWSSPNLTIISPVYFYINEEQILISDRSTVKVNGSLVSIPFVTGLSTKIYSQEGFLVIDSGPDIQIRYNGFNVIKITIGDRLQNKVCGLCGNFNGDPADDYATLRGKPVVSSVVLAQSWKTNGMQKSCNELQYSQYAASCDNVQIQKLQSDSYCLKLTDMKGFFQPCYGLLDPLPFYESCFLDGCYNRKQVQLCGSLAAYGEACRTFGILGTEWIEKENCSGVVEDPCAGADCPNRTCELDDGGELCGCIEPPPYGNTTHDIIDAEVTCKAAQMEVSISKCKLFQLGFEREGVRVNDRHCPGIEGEDFISFQINNTKGNCGNLVQSNSTHIVYKNTVWIESANNTGNIITRDRTINVEFSCAYELDIKISLDSVVRPMLSVINLTVPTQEGSFTTKMALYKNSSYKHPYRQGEVVLTTRDVLYVGVFVVGADSNHLILMLNKCYATPSRDSNDKLRYFIIEGGCQNLKDNTIGIEENGVSLTCRFHVTVFKFIGDYDEVHLHCAVSLCDSEKYSCKINCPQHRRSASAFAQEAHEQILSVGPIRRKRSDWCEDNGGCEQICTSQADGPLCSCVTGTLQGDGKSCRASSSSADSRAQASLLVVAQLWLWAALQDPTS", "length": 2151, "header": "tr|A0A8V1A4A4-1|A0A8V1A4A4_CHICK Isoform 1 of Alpha-tectorin OS=Gallus gallus OX=9031 GN=TECTA PE=4 SV=1 CANONICAL=A0A8V1A4A4-1" }, "locus": { "chromosome": "24", "start_pos": 3612502, "end_pos": 3591932, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010062940.1", "url": "https://www.ensembl.org/id/ENSGALT00010062940.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038874.1", "url": "https://www.ensembl.org/id/ENSGALP00010038874.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1981, "start_aa": "Thr", "end_pos": 1981, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1981", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:395686", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395686", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8M3ASW3-1", "protein_name": "Alpha-tectorin", "gene_name": "tecta", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MVRTGTLVSLLQLFSTLVPSGAFSQDTLYPFGPAHRDLETPKMDDGSSPEIPLLIPFIFFNVPYRSLYVNNNGVISFNIQVSQFTPEAFPLSDSRSFIAPLWADVHNGIRGDVYYRESTDTEILERATQDVRKYFKNMVSFTATWVFITTWNQVTFYGGSQTTPVNTFQAVLISDGHAYFSMFNYGEIHWSTGTASGGDPLTGLGGTTAQAGFNGGDVSHFFNLPGSRSNEVVNIEQTTNVNVPGRWFFRIDADQIDPANGCSYIGRFYRRGEVFWLSDQCTQRCRCLDLDNEVICHETPCGQLETCEQVEGAYYCQPTRTSTCVVFGDPHYHTFDGFLYHFQGTCSYLLARPCWEMPGLPFFSVEAKNENRGVPTVSWLRDVTVEVYNHRVTLPKGTLGTVQVDGLIKTLPVQLQLGAVKVYQSGVAVALETDFGLLVTYDGLHYASISLPSSYFNNTCGLCGNYNDDPADDPVLPDGSLAESVVELGGSWRAEDTDFRCTDGCAQNCSMCEPAAEAFYFRSDYCGLINKTDGPFRDCRAVVDPTAFVYSCVYDMCSNRDNITTLCQAIQAYALACQALGVTIRPWRSRSFCALTCPENSHYQVCTSACPASCSDLTSHLYCAHPCTEGCQCDQGYVLSGSRCVRRFECGCERDGLYYALNETFWAGEGGEVGEDCSQRCVCGPAGEVKCFNDSCGEGEVCAAEVGLLGCYPRREAICSLSQSQILATFDGSTMPFPDESSFYLVKTLGRLPANVTSVEVKIGRKLVNKGPTWLRPVVVRVGHLEAQIGGSDFDLIKVNGEPAIVPYVHPVEPLMIYRSSGNTTVIEWSGLVRTRYSRQGLLNITLSTLFYNTTCGLCGFFNGDPIDDLRLPSGRQADSADQFIESWRAIADDLTCNGDCEDLYRMCTDLRQYQSPWLCGNINDPGNSSFLACHTAVNPSPFFRNCLYNMCVREGNRSALCNSLQAYASACQDAQINLGTWRSATNCPLPCPENSHFDECTSACPLTCSNLDEPEEPCPLPCSEGCQCEEGFALRDGICVARSDCGCFYLGRQLATNETFWTDWECQERCFCNGTDNSVYCTFSPCHPEEYCQENEGLFFCQPRTEAMCAVAGYAHFLPFGGVPFDLQSSCTLRLATTDCGEGDEDSFGGLDSAETVLGGLPNFQLSVRNEERDTGQAIWVRGFVLEVYGYEIEVSRSFKHTVTVNKERLYLPLKLGPGKVNIYTLGLQLLVETDFGLKVAFDWNTLLLLTLPRSLFNATCGLCQGLPISGPALSVTEWGMAWADRDTFCQVGCGDSCPRCGLVERGLAAEVPAQVTDAVGNIDMDNGNPGNRFHFAEGLYVYVEPEAVRLCGLIIDRGGVFARCHSKVAPAYFYQSCLQDTCVDQGARETICNWLQIYASTCQTQGVPLIGWRSSTPCVWSCPVNSHYSSCMMACQPQCAPARGQRDCNQYCVEGCQCDQGYVLNGKSCILNQNCGCYTDGKYYEPKQLFWNSDCTKRCQCIGRNLIQCDPRRCKAEEECVLRHGVRGCFARRNQHCVASGGGVFRTFDGASLRLPASCSFVLSTICHKLPELSFQLIANFDKWSTPNLTTISHAYLYINEENILISGNTVKVNGTPVSVPFVTGLMTRVSTSEGFLVIDTPQDIQVRYNRFNTLSITMGPRLQNKVCGLCGNFNGDPTDDYITSRGKPAVSALELAQSWKTNGMQNSCDETQYVALAQSCDNTAVSELQGEDNCLKLTDLKGFFQPCHGLLDPHPFYQSCYMDGCYNHRKAQVCGSMAAYAEACRSFGTLTTKWITQENCSEWIYDPCAGEICSNNTCEQENGELCGCPELPNNDISEDDIIQAEVTCKHAQMEVSISKCRLFQLGFEREDVRINDQHCPGIEGEDFISFHINNTKGHCGSIVQSNGTHIMYKNTVWIESLNNTGSVVTRDKMINVEFSCAYELDIKISLETVLKPMLSVINLTLPTQEGNFITKMALYKNASYRHPYREGEVVLSTRDVLFVGVFVEGADDKQLILIVNMCWATPSRYSNDRLRYIIIERGCPNIKDNTIGMAENGVSLTCRFHVTVFKFIGDYDEVHLHCDVTLCDSETNACKVNCPHNKRSYTDYSQHKEQILSVGPIRRRDSDWCEENNGGCEQICTSQVTGAVCSCVTGMLQRDGKSCRVTSMSTDLQPLLLLAAAVVSVNIVLQTHTSVFFS", "length": 2201 }, "evidence": [ { "id": "A0A8V1A4A4", "url": "https://omabrowser.org/oma/group/A0A8V1A4A4/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "D4A7Z6-1", "protein_name": "Alpha-tectorin", "gene_name": "Tecta", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNYSSLLRIWVSFIFALVRHQAQPRELMYPFWQNDTRTPKVDDGSSSEIKLAIPVFFFGVPYRTVYVNNNGVVSFNVLVSQFTPESFPLTDGRAFIAPFWADVHNGIRGEIYYRETMDSAILRRATKDIRKYFKDMTTFSATWVFIVTWEEVTFYGGSSTTPVNTFQAVLVSDGSYTFTLFNYYEINWTTGTASGGDPLTGLGGVMAQAGFNGGNLTNFFSLPGSRTPEIVNIQETTNVNVPGRWAFKVDGKEIDPANGCTSRGQFLRRGEVFWDDLNCTIKCRCLDFNNEIYCQEASCSPYEVCEPKGRFFYCSPVETSTCVVFGEPHYHTFDGFLFHFQGSCAYLLARQCLQTSSLPFFSVEAKNEHRGGSAVSWVKELSVEVNGYKILIPKGSYGKVKVNDLVTSLPVTLELGAVKIYQSGMSTAVETDFGLLVTFDGQHYASISIPGSYINSTCGLCGNYNKNPLDDFLRPDGRPAMSVLDLGESWRVYHTDWKCGSGCIDNCTQCDAATEALYFGSDYCGFLNKTDGPLWECGTVVDATAFVHSCVYDLCSVRDNGTLLCQAIQAYALVCQALGIPIGDWRIQTGCVSTVRCPSFSHYSVCTSSCPDTCSDLTASQNCATPCTEGCECNEGFVLSTSQCVPLHKCGCDFEGHYYTMGEFFWATANCTVQCLCEEGGDVYCFNKTCRSGEVCAVEDGYQGCFPKRETVCLLSQNQVLHTFDGAAYAFPSELSYTLLKTCPERPEYLEIDINKRKPDAGPAWLRGVRILVADQEVKIGGVGALEVKLNGQDVELPFFHPSGRLEIHRNKNSTTVESKGVVSVQYSDVGLLYIRLSTMYFNCTGGLCGFFNANASDEFCLPNGKCTDNLAVFLESWTTFEEICNGECGDLLKACNNDSELLKFYRSRSRCGIINDPSNSSFLECHGVVNVTAYYRTCLFRLCQSGGNESELCDSVARYASACKNADVEVGPWRTYDFCPLECPENSHFEECMTCTETCETLALGPICVDSCSEGCQCDEGYALQGSQCVTRSECGCNFEGHQLATNETFWVDQDCQIFCYCNGTDNSVHCETIPCRDDDYCMEESGLYYCQPRTDASCIVSGYGHYLTFDGYPFDFQTSCPLILCTTGSRSISDSFPKFIVTAKNEDRDPSLALWVKQVDVTVFGYSIVIHRAYKHTVLVNNERLYLPLKLGQGKINIFSFGFHVVVETDFGLKVVYDWKTFLSITVPRSMQNSTYGLCGRYNGNPGDDLEMPMGLLALSINEFGQSWVKRDTFCQVGCGDRCPSCAKVEGFSKVQQLCSLIPNQNAGFAKCHSKVNPTFFYKNCLFDSCIDGGAVQTACSWLQNYASTCQTQGVAVTGWRNYTSCSVTCPPNSHYESCVSVCQPRCAAIRLKSDCNHYCVEGCQCDAGYVLNGKSCILPHNCGCYSDGKYYEPKQLFWNGDCTRRCRCFRRNLIQCDPRQCKSDEECALRSGVRGCFSTKTSYCLAAGGGVFRTFDGAFLRFPANCAFVLSTICQKLPDISFQLIINFDKWSSPNLTIISPVYFYINEEQILINDRNTVKVNGTQVNVPFITGLATKIYSSEGFLVIDTSPDIQIYYNGFNVIKISISERLQNKVCGLCGNFNGDMTDDYVTLRGKPVVSSVVLAQSWKTNGMQKRPLTPSCNELQFSQYAATCDNVHIQAMQGDGYCLKLTDMKGFFQPCYGLLDPLPFYESCYLDGCYNHKKFQLCGSLAAYGEACRSFGILSTEWIEKENCSGVVEDPCVGADCPNRTCELDNGGELCGCIEPPPYGNNSHDIIDAEVTCKAAQMEVSISKCKLFQLGFEREGVRINDRQCSGIEGEDFISFQINNTKGNCGNVVQSNGTHIMYKNTIWIESANNTGNIITRDRTINVEFSCAYELDIKISLDSVVKPMLSVINLTVPTQEGSFTTKMALYKNASYKHPYRQGEVVLTTRDVLYVGVFVVGADSTHLILTLNKCYATPSRDSNDKLRYFIIEGGCQNIKDNTIGIEENGVSLTCRFHVTVFKFIGDYDEVHLHCAVSLCDSEKYSCKINCPQNSRIATDYSKEHKEQIISVGPIRRKRLDWCEDNGGCEQVCTSRVDGPLCSCVTGSLQEDGRSCRASNSSVEPQVWTLLLIMTQISLWHFVYQSGATS", "length": 2155 }, "evidence": [ { "id": "A0A8V1A4A4", "url": "https://omabrowser.org/oma/group/A0A8V1A4A4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O08523-1", "protein_name": "Alpha-tectorin", "gene_name": "Tecta", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNYSSLLRIWVSFIFALVRHQAQPRELMYPFWQNDTRTPKVDDGSSSEIKLAIPVFFFGVPYRTVYVNNNGVVSFNVLVSQFTPESFPLTDGRAFIAPFWADVHNGIRGEIYYRETMDPAILRRATKDIRKYFKDMTTFSATWVFIVTWEEVTFYGGSSTTPVNTFQAVLVSDGSYTFTLFNYYEINWTTGTASGGDPLTGLGGVMAQAGFNGGNLTNFFSLPGSRTPEIVNIQETTNVNVPGRWAFKVDGKEIDPANGCTSRGQFLRRGEVFWDDLNCTIKCRCLDFNNEIYCQEASCSPYEVCEPKGRFFYCSPVETSTCVVFGEPHYHTFDGFLFHFQGSCAYLLARQCLQTSSLPFFSVEAKNEHRGGSAVSWVKELSVEVNGYKILIPKGSYGKVKVNDLVTSLPVTLELGAVKIYQSGMSTAVETDFGLLVTFDGQHYASISIPGSYINSTCGLCGNYNKNPLDDFLRPDGRPAMSVLDLGESWRVYHADWKCGSGCVDNCTQCDAATEALYFGSDYCGFLNKTDGPLWECGTVVDATAFVHSCVYDLCSVRDNGTLLCQAIQAYALVCQALGIPIGDWRIQTGCVSTVRCPSFSHYSVCTSSCPDTCSDLTASQNCATPCTEGCECNEGFVLSTSQCVPLHKCGCDFDGHYYTMGEFFWATANCTVQCLCEEGGDVYCFNKTCRSGEVCAVEDGYQGCFPKRETVCLLSQNQVLHTFDGAAYAFPSELSYTLLKTCPERPEYLEIDINKKKPDAGPAWLRGVRILVADQEVKIGGVGALEVKLNGQDVELPFFHPSGRLEIHRNKNSTTVESKGVVSVQYSDVGLLYIRLSTMYFNCTGGLCGFFNANASDEFCLPNGKCTDNLAVFLESWTTFEEICNGECGDLLKACNNDSELLKFYRSRSRCGIINDPSNSSFLECHGVVNVTAYYRTCLFRLCQSGGNESELCDSVARYASACKNADVEVGPWRTYDFCPLECPENSHFEECMTCTETCETLALGPICVDSCSEGCQCDEGYALQGSQCVPRSECGCNFEGHQLATNETFWVDQDCQIFCYCNGTDNSVHCETIPCRDDEYCMEESGLYYCQPRTDASCIVSGYGHYLTFDGYPFDFQTSCPLILCTTGSRPISDSFPKFIVTAKNEDRDPSLALWVKQVDVNVFGYSIVIHRAYKHTVLVNNERLYLPLKLGQGKINIFSFGFHVVVETDFGLKVVYDWKTFLSITVPRSMQNGTYGLCGRYNGNPDDDLEMPMGLPALSINEFGQSWVKRDTFCQVGCGDRCPSCAKVEGFSKVQQLCSLIPNQNAGFAKCHSKVNPTFFYKNCLFDSCIDGGAVQTACSWLQNYASTCQTQGIAVTGWRNYTSCSVTCPPNSHYESCVSVCQPRCAAIRLKSDCNHYCVEGCQCDAGYVLNGKSCILPHNCGCYSDGKYYEPKQLFWNGDCTRRCRCFRRNLIQCDPRQCKSDEECALRSGVRGCFSTKTSYCLAAGGGVFRTFDGAFLRFPANCAFVLSTICQKLPDISFQLIINFDKWSSPNLTIISPVYFYINEEQILINDRNTVKVNGTQVNVPFITGLATKIYSSEGFLVIDTSPDIQIYYNGFNVIKISISERLQNKVCGLCGNFNGDMTDDYVTLRGKPVVSSVVLAQSWKTNGMQKRPLAPSCNELQFSQYAATCDNVHIQAMQGDGYCLKLTDMKGFFQPCYGLLDPLPFYESCYLDGCYNHKKFQLCGSLAAYGEACRSFGILSTEWIEKENCSGVVEDPCVGADCPNRTCELDNGGELCGCIEPPPYGNNSHDIIDAEVTCKAAQMEVSISKCKLFQLGFEREGVRINDRQCSGIEGEDFISFQINNTKGNCGNIVQSNGTHIMYKNTIWIESANNTGNIITRDRTINVEFSCAYELDIKISLDSVVKPMLSVINLTVPTQEGSFTTKMALYKNASYKHPYRQGEVVLTTRDVLYVGVFVVGADSTHLILTLNKCYATPSRDSNDKLRYFIIEGGCQNIKDNTIGIEENGVSLTCRFHVTVFKFIGDYDEVHLHCAVSLCDSEKYSCKINCPQNSRIATDYSKEHKEQIISVGPIRRKRLDWCEDNGGCEQICTSRVDGPLCSCVTGSLQEDGRSCRASNSSVELQVWTLLLIMTQISLWHLIYKSGATS", "length": 2155 }, "evidence": [ { "id": "A0A8V1A4A4", "url": "https://omabrowser.org/oma/group/A0A8V1A4A4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "O75443-1", "protein_name": "Alpha-tectorin", "gene_name": "TECTA", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNYSSFLRIWVSFIFALVQHQAQPRELMYPFWQNDTKTPKVDDGSSSEIKLAIPVFFFGVPYRTVYVNNNGVVSFNVLVSQFTPESFPLTDGRAFVAPFWADVHNGIRGEIYYRETMEPAILKRATKDIRKYFKDMATFSATWVFIVTWEEVTFYGGSSTTPVNTFQAVLVSDGSYTFTLFNYYEINWTTGTASGGDPLTGLGGVMAQAGFNGGNLTNFFSLPGSRTPEIVNIQETTNVNVPGRWAFKVDGKEIDPANGCTSRGQFLRRGEVFWDDLNCTVKCRCLDFNNEIYCQEASCSPYEVCEPKGKFFYCSAVETSTCVVFGEPHYHTFDGFLFHFQGSCAYLLARQCLQTSSLPFFSVEAKNEHRRGSAVSWVKELSVEVNGYKILIPKGSYGRVKVNDLVTSLPVTLDLGTVKIYQSGISTAVETDFGLLVTFDGQHYASISVPGSYINSTCGLCGNYNKNPLDDFLRPDGRPAMSVLDLGESWRVYHADWKCDSGCVDNCTQCDAATEALYFGSDYCGFLNKTDGPLWECGTVVDPTAFVHSCVYDLCSVRDNGTLLCQAIQAYALVCQALGIPIGDWRTQTGCVSTVQCPSFSHYSVCTSSCPDTCSDLTASRNCATPCTEGCECNQGFVLSTSQCVPLHKCGCDFDGHYYTMGEFFWATANCTVQCLCEEGGDVYCFNKTCGSGEVCAVEDGYQGCFPKRETVCLLSQNQVLHTFDGASYAFPSEFSYTLLKTCPERPEYLEIDINKKKPDAGPAWLRGLRILVADQEVKIGGIGASEVKLNGQEVELPFFHPSGKLEIYRNKNSTTVESKGVVTVQYSDIGLLYIRLSTTYFNCTGGLCGFYNANASDEFCLPNGKCTDNLAVFLESWTTFEEICNGECGDLLKACNNDSELLKFYRSRSRCGIINDPSNSSFLECHGVVNVTAYYRTCLFRLCQSGGNESELCDSVARYASACKNADVEVGPWRTYDFCPLECPENSHFEECITCTETCETLTLGPICVDSCSEGCQCDEGYALLGSQCVTRSECGCNFEGHQLATNETFWVDLDCQIFCYCSGTDNRVHCETIPCKDDEYCMEEGGLYYCQARTDASCIVSGYGHYLTFDGFPFDFQTSCPLILCTTGSRPSSDSFPKFVVTAKNEDRDPSLALWVKQVDVTVFGYSIVIHRAYKHTVLVNSERLYLPLKLGQGKINIFSFGFHVVVETDFGLKVVYDWKTFLSITVPRSMQNSTYGLCGRYNGNPDDDLEMPMGLLASSVNEFGQSWVKRDTFCQVGCGDRCPSCAKVEGFSKVQQLCSLIPNQNAAFSKCHSKVNPTFFYKNCLFDSCIDGGAVQTACSWLQNYASTCQTQGITVTGWRNYTSCTVTCPPNSHYESCVSVCQPRCAAIRLKSDCSHYCVEGCHCDAGYVLNGKSCILPHSCGCYSDGKYYEPKQLFWNSDCTRRCRCFRRNVIQCDPRQCKSDEECALRNGVRGCFSTKTSYCLAAGGGVFRTFDGAFLRFPANCAFVLSTICQKLPDISFQLIINFDKWSAPNLTIISPVYFYINEEQILINDRNTVKVNGTQVNVPFITGLATKIYSSEGFLVIDTSPDIQIYYNGFNVIKISISERLQNKVCGLCGNFNGDLTDDYVTLRGKPVVSSVVLAQSWKTNGMQKRPLAPSCNELQFSQYAAMCDNVHIQKMQGDGYCLKLTDMKGFFQPCYGLLDPLPFYESCYLDGCYSHKKFQLCGSLAAYGEACRSFGILSTEWIEKENCSGVVEDPCVGADCPNRTCELGNGRELCGCIEPPPYGNNSHDIIDAEVTCKAAQMEVSISKCKLFQLGFEREGVRINDRQCTGIEGEDFISFQINNTKGNCGNIVQSNGTHIMYKNTLWIESANNTGNIITRDRTINVEFSCAYELDIKISLDSVVKPMLSVINLTVPTQEGSFITKMALYKNASYKHPYRQGEVVLTTRDVLYVGVFVVGADATHLILTLNKCYATPTRDSNDKLRYFIIEGGCQNLKDNTIGIEENAVSLTCRFHVTVFKFIGDYDEVHLHCAVSLCDSEKYSCKITCPHNSRIATDYTKEPKEQIISVGPIRRKRLDWCEDNGGCEQICTSRVDGPLCSCVTGTLQEDGKSCRASNSSMELQVWTLLLIMIQISLWHFVYKSGTTS", "length": 2155 }, "evidence": [ { "id": "A0A8V1A4A4", "url": "https://omabrowser.org/oma/group/A0A8V1A4A4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A4A4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4A4" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A4A4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4A4" } ], "pmid": "" }, { "name": "extracellular matrix", "id": "GO:0031012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031012", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A4A4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4A4" } ], "pmid": "" }, { "name": "side of membrane", "id": "GO:0098552", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098552", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A4A4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4A4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "cell-matrix adhesion", "id": "GO:0007160", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007160", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A4A4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4A4" } ], "pmid": "" }, { "name": "sensory perception of sound", "id": "GO:0007605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007605", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A4A4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4A4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "extracellular matrix structural constituent", "id": "GO:0005201", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005201", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A4A4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4A4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1048, "end_pos": 1050, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1064, "end_pos": 1066, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1074, "end_pos": 1076, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1238, "end_pos": 1240, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1367, "end_pos": 1369, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1541, "end_pos": 1543, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1568, "end_pos": 1570, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1754, "end_pos": 1756, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1770, "end_pos": 1772, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1792, "end_pos": 1794, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1849, "end_pos": 1851, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1862, "end_pos": 1864, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1878, "end_pos": 1880, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1918, "end_pos": 1920, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1937, "end_pos": 1939, "annotation": "n_glycosylation_sequon" }, { "start_pos": 215, "end_pos": 217, "annotation": "n_glycosylation_sequon" }, { "start_pos": 278, "end_pos": 280, "annotation": "n_glycosylation_sequon" }, { "start_pos": 34, "end_pos": 36, "annotation": "n_glycosylation_sequon" }, { "start_pos": 455, "end_pos": 457, "annotation": "n_glycosylation_sequon" }, { "start_pos": 506, "end_pos": 508, "annotation": "n_glycosylation_sequon" }, { "start_pos": 528, "end_pos": 530, "annotation": "n_glycosylation_sequon" }, { "start_pos": 560, "end_pos": 562, "annotation": "n_glycosylation_sequon" }, { "start_pos": 687, "end_pos": 689, "annotation": "n_glycosylation_sequon" }, { "start_pos": 813, "end_pos": 815, "annotation": "n_glycosylation_sequon" }, { "start_pos": 843, "end_pos": 845, "annotation": "n_glycosylation_sequon" }, { "start_pos": 855, "end_pos": 857, "annotation": "n_glycosylation_sequon" }, { "start_pos": 898, "end_pos": 900, "annotation": "n_glycosylation_sequon" }, { "start_pos": 920, "end_pos": 922, "annotation": "n_glycosylation_sequon" }, { "start_pos": 931, "end_pos": 933, "annotation": "n_glycosylation_sequon" }, { "start_pos": 949, "end_pos": 951, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1A4A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4A4" }, { "id": "PS51220", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51220" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "NIDO", "eco_id": "ECO_0000259", "start_pos": 98, "end_pos": 252, "start_aa": "Pro", "end_aa": "Arg", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1A4A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4A4" }, { "id": "PS51233", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51233" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "VWFD", "eco_id": "ECO_0000259", "start_pos": 320, "end_pos": 500, "start_aa": "Ser", "end_aa": "Ser", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1A4A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4A4" }, { "id": "PS51034", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51034" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "ZP", "eco_id": "ECO_0000259", "start_pos": 1803, "end_pos": 2057, "start_aa": "Thr", "end_aa": "His", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 1981 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1048, "end_pos": 1050 }, { "start_pos": 1064, "end_pos": 1066 }, { "start_pos": 1074, "end_pos": 1076 }, { "start_pos": 1238, "end_pos": 1240 }, { "start_pos": 1367, "end_pos": 1369 }, { "start_pos": 1541, "end_pos": 1543 }, { "start_pos": 1568, "end_pos": 1570 }, { "start_pos": 1754, "end_pos": 1756 }, { "start_pos": 1770, "end_pos": 1772 }, { "start_pos": 1792, "end_pos": 1794 }, { "start_pos": 1849, "end_pos": 1851 }, { "start_pos": 1862, "end_pos": 1864 }, { "start_pos": 1878, "end_pos": 1880 }, { "start_pos": 1918, "end_pos": 1920 }, { "start_pos": 1937, "end_pos": 1939 }, { "start_pos": 215, "end_pos": 217 }, { "start_pos": 278, "end_pos": 280 }, { "start_pos": 34, "end_pos": 36 }, { "start_pos": 455, "end_pos": 457 }, { "start_pos": 506, "end_pos": 508 }, { "start_pos": 528, "end_pos": 530 }, { "start_pos": 560, "end_pos": 562 }, { "start_pos": 687, "end_pos": 689 }, { "start_pos": 813, "end_pos": 815 }, { "start_pos": 843, "end_pos": 845 }, { "start_pos": 855, "end_pos": 857 }, { "start_pos": 898, "end_pos": 900 }, { "start_pos": 920, "end_pos": 922 }, { "start_pos": 931, "end_pos": 933 }, { "start_pos": 949, "end_pos": 951 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A4A8-1", "uniprot_ac": "A0A8V1A4A8", "uniprot_id": "A0A8V1A4A8_CHICK", "mass": { "chemical_mass": 24001.0, "monoisotopic_mass": 24001.0 }, "refseq": { "ac": "XP_004936791", "name": "dynein light chain Tctex-type 4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004936791" }, "gene_names": [ { "name": "TCTEX1D4", "type": "recommended", "evidence": [ { "id": "A0A8V1A4A8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4A8" } ] }, { "name": "TCTEX1D4", "type": "synonym", "evidence": [ { "id": "XP_004936791", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004936791" } ] } ], "protein_names": [ { "name": "Dynein light chain Tctex-type 4", "type": "synonym", "evidence": [ { "id": "A0A8V1A4A8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4A8/entry#names_and_taxonomy" } ] }, { "name": "dynein light chain Tctex-type 4", "type": "synonym", "evidence": [ { "id": "XP_004936791", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004936791" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052539.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004936791.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004936791", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004936791" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A4A8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4A8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TCTEX1D4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4A8", "locus": {} } ], "crossref": [ { "id": "A0A8V1A4A8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A4A8", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd21461", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21461", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "101747461", "url": "https://www.ncbi.nlm.nih.gov/gene/101747461", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR005334", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005334", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038586", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038586", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:101747461", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:101747461", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CPPRYKL", "url": "https://omabrowser.org/oma/group/CPPRYKL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A4A8", "url": "https://www.orthodb.org/?gene=A0A8V1A4A8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21255", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21255", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21255:SF55", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21255:SF55", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03645", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03645", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004936791", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004936791", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1A4A8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4A8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A4A8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4A8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAEQPSLELAPSTQVTAEDGTEAPQPRATRRGSQPTAPSRGAEEGKAPQLLSRRSSVLSTLLGPPGSRRSSLGAAPGGKRPSVGPWLLHSRVSFTGLPLFQPIPETHLENTYRMRPEEGCRFNAGRVQRVLEGALAGVLGGTAYSPQGSTVLVQSLAELLRSRAKEVVPPRYKLVCHVLLGQQGQQSMLVASRALWDPESDSFASASFCNASLFAVATVHGVYFE", "length": 225, "header": "tr|A0A8V1A4A8-1|A0A8V1A4A8_CHICK Isoform 1 of Dynein light chain Tctex-type 4 OS=Gallus gallus OX=9031 GN=TCTEX1D4 PE=3 SV=1 CANONICAL=A0A8V1A4A8-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A4A8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4A8/entry#A0A8V1A4A8-1", "sequence": { "sequence": "MAEQPSLELAPSTQVTAEDGTEAPQPRATRRGSQPTAPSRGAEEGKAPQLLSRRSSVLSTLLGPPGSRRSSLGAAPGGKRPSVGPWLLHSRVSFTGLPLFQPIPETHLENTYRMRPEEGCRFNAGRVQRVLEGALAGVLGGTAYSPQGSTVLVQSLAELLRSRAKEVVPPRYKLVCHVLLGQQGQQSMLVASRALWDPESDSFASASFCNASLFAVATVHGVYFE", "length": 225, "header": "tr|A0A8V1A4A8-1|A0A8V1A4A8_CHICK Isoform 1 of Dynein light chain Tctex-type 4 OS=Gallus gallus OX=9031 GN=TCTEX1D4 PE=3 SV=1 CANONICAL=A0A8V1A4A8-1" }, "locus": { "chromosome": "8", "start_pos": 20478561, "end_pos": 20477887, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010062949.1", "url": "https://www.ensembl.org/id/ENSGALT00010062949.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038879.1", "url": "https://www.ensembl.org/id/ENSGALP00010038879.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:101747461", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:101747461", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287BCE1-1", "protein_name": "Dynein light chain Tctex-type 4", "gene_name": "DYNLT4", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAGRPVPAGRQEEELAKDPGQKLSLARPPGRLPSIDETRPAGPGPASRRGSVLGPASSFSRRNSLAGAGAGPGGRRPSLGPVPPLGWRVSFSGLPLGPARRPAPSYRTEPAPGERWEAARAQRALEALAAGLRDARYVGAEAGRLARELCDLARVHLRELSPPRYKLVCSVVLGPRAGQGVHVASRALWDTACDGLASATVTNASLFAVATVHGLYCE", "length": 218 }, "evidence": [ { "id": "A0A8V1A4A8", "url": "https://omabrowser.org/oma/group/A0A8V1A4A8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "D3Z860-1", "protein_name": "BTB domain containing 19", "gene_name": "Btbd19", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MENPGLVVRGQAAPFSTALRSLINNPRYSDICFVVGQERQEVFAHRCLLACRCNFFQRLLGPGIPSPVVLSTVPAEAFLAVLEFLYTNSVKLHRYSVLEVLTAAVEYGLEELRELCLEFVVKVLDVELVCEALQVAVTFGLEPLQKRCIAFIETHSQEALRTRGFLELSATALLPVLRSDKLCVDEAELIQAARSWARVGAVSGVWGLDDDAEAAQAAGFCKRARGTGSRLSSIGGVGATRGRGGSSSGSRAEIGSARPSGAKRPGRTEPTGASHSGADASNQTYIHSATWGRGARTEGQGLPACMVTRFPLQVEQIVEAWKCHALRRGDAARSALCRRRRGTLPRDHHRFLDLRF", "length": 356 }, "evidence": [ { "id": "A0A8V1A4A8", "url": "https://omabrowser.org/oma/group/A0A8V1A4A8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1MM02-1", "protein_name": "Dynein light chain Tctex-type 4", "gene_name": "DYNLT4", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAGRPVAPGRQEEEEAKDHGLKLSAARPLGHLPSIDGTRPAGLGPASRRGSVLGPVLSFSRRNSLAGPSAGPGGRRPSLGPVPPLGSRVSFSGLPLAPARRMAPSYRTEPAPGERWETARAQQALEAALAEGLRDACYSGAEAGRLAQELCELVRRRLRELSPPRYKLVCSVVLGQRAGQGVRVVSRALWDAACDGLASAAVTNASLFAVATVHGLYCE", "length": 219 }, "evidence": [ { "id": "A0A8V1A4A8", "url": "https://omabrowser.org/oma/group/A0A8V1A4A8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3GYR5-1", "protein_name": "Tctex1 domain-containing protein 4", "gene_name": "Tctex1d4", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAGRTLLSGRQEEETTKDLALKLPPGKSGGHLPSIDETRPVGPGPASRRGSLLSLHPSFSRRNSLAGPLVGTGGRRPSLGPMPPFGSRVSFSGLPLVPARRMAPSYRTEPAPGERWEAASAQCVLEAALHAGLSNVCYSGSEAGKLAQALCEQIRMRVRELCLPRYKLVCSVVLGPREKQGVHVVSRALWDAVHDGLASATFTNTSLFAVATVHAVYWE", "length": 219 }, "evidence": [ { "id": "A0A8V1A4A8", "url": "https://omabrowser.org/oma/group/A0A8V1A4A8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q5JR98-1", "protein_name": "Dynein light chain Tctex-type 4", "gene_name": "DYNLT4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASRPLPPGRQEEENAKDSGRKPSPVRPRGCLPSIDEARPAGPGPAPASRRGSMLGLAASFSRRNSLVGPGAGPGGQRPSLGPVPPLGSRVSFSGLPLAPARWVAPSYRTEPVPGERWEAARAQRALEAALAAGLHDACYSSDEAARLVRELCEQVHVRLRELSPPRYKLVCSVVLGPRAGQGVHVVSRALWDVARDGLASVSYTNTSLFAVATVHGLYCE", "length": 221 }, "evidence": [ { "id": "A0A8V1A4A8", "url": "https://omabrowser.org/oma/group/A0A8V1A4A8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8CDY7-1", "protein_name": "Dynein light chain Tctex-type 4", "gene_name": "Dynlt4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MACRTLPSRRQEEETTKDLALKLPPGKPGGHLPSIDETRPIGPGPASRRGSLPGLHPSFSRRNSLAGPLVGPGGRRPSLGPVPPLGSRVSFSGLPLMLPRRMAPSYRLEPAPGEHWEAAGAQRALEAALTTQLNGVCYCGSEAGKLVQALCEQIHTRVRELNLPRYKLVCNVVLGPREGQGVHVVSRALWDAVHDGLASATFTNPSLFAVATVHAVYWE", "length": 219 }, "evidence": [ { "id": "A0A8V1A4A8", "url": "https://omabrowser.org/oma/group/A0A8V1A4A8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A4A8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4A8" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A4A8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4A8" } ], "pmid": "" }, { "name": "acrosomal vesicle", "id": "GO:0001669", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001669", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A4A8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4A8" } ], "pmid": "" }, { "name": "microtubule organizing center", "id": "GO:0005815", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005815", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A4A8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4A8" } ], "pmid": "" }, { "name": "sperm flagellum", "id": "GO:0036126", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036126", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A4A8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4A8" } ], "pmid": "" }, { "name": "axoneme", "id": "GO:0005930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005930", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A4A8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4A8" } ], "pmid": "" }, { "name": "cytoplasmic dynein complex", "id": "GO:0005868", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005868", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A4A8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4A8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "microtubule-based movement", "id": "GO:0007018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007018", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A4A8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4A8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein phosphatase 1 binding", "id": "GO:0008157", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008157", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A4A8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4A8" } ], "pmid": "" }, { "name": "dynein intermediate chain binding", "id": "GO:0045505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045505", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A4A8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4A8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 210, "end_pos": 212, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 210, "end_pos": 212 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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"gene_names": [ { "name": "ST7L", "type": "recommended", "evidence": [ { "id": "A0A8V1A4C5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4C5" } ] } ], "protein_names": [ { "name": "Suppressor of tumorigenicity 7 protein-like", "type": "recommended", "evidence": [ { "id": "A0A8V1A4C5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4C5/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A4C5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4C5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ST7L", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4C5", "locus": { "chromosome": "26", "start_pos": 3553619, "end_pos": 3573782, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027438", "url": "https://www.ensembl.org/id/ENSGALG00010027438" } ] } } ], "crossref": [ { "id": "A0A8V1A4C5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A4C5", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd11557", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11557", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR007311", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007311", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A4C5", "url": "https://www.orthodb.org/?gene=A0A8V1A4C5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A4D0", "url": "https://www.orthodb.org/?gene=A0A8V1A4D0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AEN2", "url": "https://www.orthodb.org/?gene=A0A8V1AEN2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12745", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12745", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12745:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12745:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04184", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04184", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1A4C5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4C5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A4C5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4C5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A4D0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4D0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A4D0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4D0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AEN2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEN2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AEN2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEN2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGAPGRAEPAGPRGWSRSGSSGLRSGDERGERGYLAGESPLLSPELRGETPPGSACPPRPFPVSPALAMADGCGTGKEPPYPGAAAALRRWEQLRRRAAAPWARGLLAVAAGLGLFYAALRVPLRLRDGLAAVTVFLSTLTPKFYFALTVTSSFISGLIFVFEWWHFRKYGTSFIEQVSVSHLRPLIGGVENSPPAPAAFSAGENEANRQNMPECKMWRNPLNLFRGAEYSRYMWVTGKEPLTYYDMNLSAQDHQNFFTCDTDALRPSDTVMQKAWRERNPQARIKAAYQALELNNDCATAYVLLAEEEATTIVDAERYFKQALKAGEMIYRKSQNCHSQSPQHEAQLRRDTNVLVYVKRRLAMCARKLGRIRESVKMMRDLMKEFPLLSMLNIHENLLEALLELQAYADVQAVLAKYDDISLPKSAAICYTAALLKARAVSERFSPETAFKRGLSTAEINAVEAIHRAVEFNPHVPKYLLEMKSLVLPPEHILKRGDSEAVAYAFFHLQHWKRIEGALHLLHCTWEGTFRMIPYPLEKGHLFYPYPSCTETADRELLPTFHEVSVYPQKELPFFIHFTAGLCSFSAMLALLTHQFPELMVVFAKAVSMVSVITVLTTFPTSLSFKNQRRCFSYSRCLLCFVTV", "length": 644, "header": "tr|A0A8V1A4C5-1|A0A8V1A4C5_CHICK Isoform 1 of Suppressor of tumorigenicity 7 protein-like OS=Gallus gallus OX=9031 GN=ST7L PE=3 SV=1 CANONICAL=A0A8V1A4C5-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A4C5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4C5/entry#A0A8V1A4C5-1", "sequence": { "sequence": "MGAPGRAEPAGPRGWSRSGSSGLRSGDERGERGYLAGESPLLSPELRGETPPGSACPPRPFPVSPALAMADGCGTGKEPPYPGAAAALRRWEQLRRRAAAPWARGLLAVAAGLGLFYAALRVPLRLRDGLAAVTVFLSTLTPKFYFALTVTSSFISGLIFVFEWWHFRKYGTSFIEQVSVSHLRPLIGGVENSPPAPAAFSAGENEANRQNMPECKMWRNPLNLFRGAEYSRYMWVTGKEPLTYYDMNLSAQDHQNFFTCDTDALRPSDTVMQKAWRERNPQARIKAAYQALELNNDCATAYVLLAEEEATTIVDAERYFKQALKAGEMIYRKSQNCHSQSPQHEAQLRRDTNVLVYVKRRLAMCARKLGRIRESVKMMRDLMKEFPLLSMLNIHENLLEALLELQAYADVQAVLAKYDDISLPKSAAICYTAALLKARAVSERFSPETAFKRGLSTAEINAVEAIHRAVEFNPHVPKYLLEMKSLVLPPEHILKRGDSEAVAYAFFHLQHWKRIEGALHLLHCTWEGTFRMIPYPLEKGHLFYPYPSCTETADRELLPTFHEVSVYPQKELPFFIHFTAGLCSFSAMLALLTHQFPELMVVFAKAVSMVSVITVLTTFPTSLSFKNQRRCFSYSRCLLCFVTV", "length": 644, "header": "tr|A0A8V1A4C5-1|A0A8V1A4C5_CHICK Isoform 1 of Suppressor of tumorigenicity 7 protein-like OS=Gallus gallus OX=9031 GN=ST7L PE=3 SV=1 CANONICAL=A0A8V1A4C5-1" }, "locus": { "chromosome": "26", "start_pos": 3573683, "end_pos": 3559375, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066510.1", "url": "https://www.ensembl.org/id/ENSGALT00010066510.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040739.1", "url": "https://www.ensembl.org/id/ENSGALP00010040739.1" } ] } }, { "isoform_ac": "A0A8V1A4D0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4C5/entry#A0A8V1A4D0-1", "sequence": { "sequence": "MGAPGRAEPAGPRGWSRSGSSGLRSGDERGERGYLAGESPLLSPELRGETPPGSACPPRPFPVSPALAMADGCGTGKEPPYPGAAAALRRWEQLRRRAAAPWARGLLAVAAGLGLFYAALRVPLRLRDGLAAVTSSFISGLIFVFEWWHFRKYGTSFIEQVSVSHLRPLIGGVENSPPAPAAFSAGENEANRQNMPECKMWRNPLNLFRGAEYSRYMWVTGKEPLTYYDMNLSAQDHQNFFTCDTDALRPSDTVMQKAWRERNPQARIKAAYQALELNNDCATAYVLLAEEEATTIVDAERYFKQALKAGEMIYRKSQNCHSQSPQHEAQLRRDTNVLVYVKRRLAMCARKLGRIRESVKMMRDLMKEFPLLSMLNIHENLLEALLELQAYADVQAVLAKYDDISLPKSAAICYTAALLKARAVSERFSPETAFKRGLSTAEINAVEAIHRAVEFNPHVPKYLLEMKSLVLPPEHILKRGDSEAVAYAFFHLQHWKRIEGALHLLHCTWEGTFRMIPYPLEKGHLFYPYPSCTETADRELLPTFHEVSVYPQKELPFFIHFTAGLCSFSAMLALLTHQFPELMVVFAKAVLRVLWPVSAPSVLASG", "length": 606, "header": "tr|A0A8V1A4D0-1|A0A8V1A4D0_CHICK Computationally mapped isoform of Suppressor of tumorigenicity 7 protein-like OS=Gallus gallus OX=9031 GN=ST7L PE=3 SV=1 CANONICAL=A0A8V1A4C5-1" }, "locus": { "chromosome": "26", "start_pos": 3573683, "end_pos": 3554556, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066519.1", "url": "https://www.ensembl.org/id/ENSGALT00010066519.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040744.1", "url": "https://www.ensembl.org/id/ENSGALP00010040744.1" } ] } }, { "isoform_ac": "A0A8V1AEN2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4C5/entry#A0A8V1AEN2-1", "sequence": { "sequence": "MADGCGTGKEPPYPGAAAALRRWEQLRRRAAAPWARGLLAVAAGLGLFYAALRVPLRLRDGLAAVTVFLSTLTPKFYFALTVTSSFISGLIFVFEWWHFRKYGTSFIEQVSVSHLRPLIGGVENSPPAPAAFSAGENEANRQNMPECKMWRNPLNLFRGAEYSRYMWVTGKEPLTYYDMNLSAQDHQNFFTCDTDALRPSDTGRDTNVLVYVKRRLAMCARKLGRIRESVKMMRDLMKEFPLLSMLNIHENLLEALLELQAYADVQAVLAKYDDISLPKSAAICYTAALLKARAVSERFSPETAFKRGLSTAEINAVEAIHRAVEFNPHVPKYLLEMKSLVLPPEHILKRGDSEAVAYAFFHLQHWKRIEGALHLLHCTWEGTFRMIPYPLEKGHLFYPYPSCTETADRELLPTFHEVSVYPQKELPFFIHFTAGLCSFSAMLALLTHQFPELMVVFAKAVLRVLWPVSAPSVLASG", "length": 477, "header": "tr|A0A8V1AEN2-1|A0A8V1AEN2_CHICK Computationally mapped isoform of Suppressor of tumorigenicity 7 protein-like OS=Gallus gallus OX=9031 GN=ST7L PE=3 SV=1 CANONICAL=A0A8V1A4C5-1" }, "locus": { "chromosome": "26", "start_pos": 3573479, "end_pos": 3554556, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066514.1", "url": "https://www.ensembl.org/id/ENSGALT00010066514.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040742.1", "url": "https://www.ensembl.org/id/ENSGALP00010040742.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A4C5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4C5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "negative regulation of cell growth", "id": "GO:0030308", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030308", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A4C5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4C5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 248, "end_pos": 250, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 248, "end_pos": 250 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A4E3-1", "uniprot_ac": "A0A8V1A4E3", "uniprot_id": "A0A8V1A4E3_CHICK", "mass": { "chemical_mass": 153877.0, "monoisotopic_mass": 153877.0 }, "refseq": {}, "gene_names": [ { "name": "SBNO1", "type": "recommended", "evidence": [ { "id": "A0A8V1A4E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4E3" } ] } ], "protein_names": [ { "name": "Protein strawberry notch homolog 1", "type": "recommended", "evidence": [ { "id": "A0A8V1A4E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4E3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A4E3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4E3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SBNO1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4E3", "locus": { "chromosome": "15", "start_pos": 5047465, "end_pos": 5018287, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010024812", "url": "https://www.ensembl.org/id/ENSGALG00010024812" } ] } } ], "crossref": [ { "id": "427694", "url": "https://www.ncbi.nlm.nih.gov/gene/427694", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026741", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026741", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026937", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026937", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039187", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039187", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057332", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057332", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:427694", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427694", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KLWMEAR", "url": "https://omabrowser.org/oma/group/KLWMEAR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A4C8", "url": "https://www.orthodb.org/?gene=A0A8V1A4C8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A4D5", "url": "https://www.orthodb.org/?gene=A0A8V1A4D5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A4E3", "url": "https://www.orthodb.org/?gene=A0A8V1A4E3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12706", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12706", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12706:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12706:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13871", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13871", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13872", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13872", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25373", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25373", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001026640", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026640", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1A4C8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4C8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A4C8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4C8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A4D5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4D5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A4D5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4D5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A4E3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4E3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A4E3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4E3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVEPGQDLLLAALSESGISPNDLFDIDSPDVVLATPTPAVQQSVPLSALDLGLETEAPAAVKQEPETVSTPALLNVRQPPSTTTFVLNQINQLPTLGTTIVMTKTTPVTTTRQTITVAKIIQTSTTTRPSVAAPAVRNALTTAPSKDQIQLKDLLKNNSLNELMKLKPPPNIAQPVATAATDLSNGAVKKEASTKEVARIWINDVKMRSFSPTMKVPAVKEEEEPEEEDEEEMGHAETYAEYMPIKLKIGLRHPDPVVETSSLSSVTPPDVWYQTSISEETIDNGWLSALQLEAITYAAQQHETFLPNGDRAGFLIGDGAGVGKGRTIAGIIYENYLLGRKRAVWFSVSNDLKYDAERDLRDIGAKNILVHSLNKFKYGKISSKHNGSVKKGVIFATYSSLIGESQSGGKYKTRLKQLLHWCGEDFDGVIVFDECHKAKNLCPVGSSKPTKTGLAVLELQNKLPKARVVYASATGASEPRNMAYMNRLGIWGEGTPFREFSDFIQAVERRGVGAMEIVAMDMKLRGMYIARQLSFSGVTFKIDEVLLSQEYVKMYNKSVKLWVSARERFQQAADLIDAEQRMKKSMWGQFWSAHQRFFKYLCIASKVKRVVQLAREEIKNGKCVVIGLQSTGEARTLEALEEGGGELNDFVSTAKGVFQSLIEKHFPAPDRKKLFSLLGIDLTAQSNNNSPRDSPCKENKIKKRKGEEVSREAKKARKTGGLAGSSSDESESESDASDNEESDNESSRFLSSGDDDDFNPFRDESSEDDEDDPWLIRKEHKKVKEKKKKKSIDPDSIQSALLASGLGSKRPSCFTSTVGTTTSSTNASANSNTNSSFVTSQDAVERAQQMKKELLDKLEKLAEDLPPNTLDELIDELGGPENVAEMTGRKGRVVSNDDGSISYESRSELDVPVEILNITEKQRFMDGDKNIAIISEAASSGISLQADRRAKNQRRRVHMTLELPWSADRAIQQFGRTHRSNQVTAPEYVFLISELAGEQRFASIVAKRLESLGALTHGDRRATETRDLSRFNFDNKYGRNALEIVMKSIVNLDSPMVSPPPDFPGDFFKDVRQGLIGVGLINVEDRSGILTLDKDYNNIGKFLNRILGMEVHQQNALFQYFSDTLNAVIQNAKKNGRYDMGILDLGSGDEKVRKADVKKFLTPGYSTSGHVELYTISVERGMSWDEATKIWAEQTGPDDGFYLSLQIRNNKKTAILVKEVNPKKKLFLVYRPNTGKQLKLETCADLKKKYKKVPSEDALPHWLEQYNSSADTCTHAYWRGNCKKAGLGLVCEVGLRCRTYYVLCGSVLSVWTKVEGVLASVSGTNVKMQIVRLRTEDGQRIVGLIIPANCVSPLVNLLSTSDQSQQLAVQQQQIWQQHHPQSITNFNNA", "length": 1389, "header": "tr|A0A8V1A4E3-1|A0A8V1A4E3_CHICK Isoform 1 of Protein strawberry notch homolog 1 OS=Gallus gallus OX=9031 GN=SBNO1 PE=3 SV=1 CANONICAL=A0A8V1A4E3-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A4C8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4E3/entry#A0A8V1A4C8-1", "sequence": { "sequence": "MVEPGQDLLLAALSESGISPNDLFDIDSPDVVLATPTPAVQQSVPLSALDLGLETEAPAAVKQEPETVSTPALLNVRQPPSTTTFVLNQINQLPTLGTTIVMTKTTPVTTTRQTITVAKIIQTSTTTRPSVAAPAVRNALTTAPSKDQIQLKDLLKNNSLNELMKLKPPPNIAQPVATAATDLSNGAVKKEASTKEVARIWINDVKMRSFSPTMKVPAVKEEEEPEEEDEEEMGHAETYAEYMPIKLKIGLRHPDPVVETSSLSSVTPPDVWYQTSISEETIDNGWLSALQLEAITYAAQQHETFLPNGDRAGFLIGDGAGVGKGRTIAGIIYENYLLGRKRAVWFSVSNDLKYDAERDLRDIGAKNILVHSLNKFKYGKISSKHNGSVKKGVIFATYSSLIGESQSGGKYKTRLKQLLHWCGEDFDGVIVFDECHKAKNLCPVGSSKPTKTGLAVLELQNKLPKARVVYASATGASEPRNMAYMNRLGIWGEGTPFREFSDFIQAVERRGVGAMEIVAMDMKLRGMYIARQLSFSGVTFKIDEVLLSQEYVKMYNKSVKLWVSARERFQQAADLIDAEQRMKKSMWGQFWSAHQRFFKYLCIASKVKRVVQLAREEIKNGKCVVIGLQSTGEARTLEALEEGGGELNDFVSTAKGVFQSLIEKHFPAPDRKKLFSLLGIDLTAQSNNNSPRDSPCKENKIKKRKGEEVSREAKKARKTGGLAGSSSDESESESDASDNEESDNESSRFLSSGDDDDFNPFRDESSEDDEDDPWLIRKEHKKVKEKKKKKSIDPDSIQSALLASGLGSKRPSCFTSTVGTTTSSTNASANSNTNSSFVTSQDAVERAQQMKKELLDKLEKLAEDLPPNTLDELIDELGGPENVAEMTGRKGRVVSNDDGSISYESRSELDVPVEILNITEKQRFMDGDKNIAIISEAASSGISLQADRRAKNQRRRVHMTLELPWSADRAIQQFGRTHRSNQVTAPEYVFLISELAGEQRFASIVAKRLESLGALTHGDRRATETRDLSRFNFDNKYGRNALEIVMKSIVNLDSPMVSPPPDFPGDFFKDVRQGLIGVGLINVEDRSGILTLDKDYNNIGKFLNRILGMEVHQQNALFQYFSDTLNAVIQNAKKNGRYDMGILDLGSGDEKVRKADVKKFLTPGYSTSGHVELYTISVERGMSWDEATKIWAEQTGPDDGFYLSLQVRRQAWD", "length": 1213, "header": "tr|A0A8V1A4C8-1|A0A8V1A4E3_CHICK Computationally mapped isoform of Protein strawberry notch homolog 1 OS=Gallus gallus OX=9031 GN=SBNO1 PE=3 SV=1 CANONICAL=A0A8V1A4E3-1" }, "locus": { "chromosome": "15", "start_pos": 5045725, "end_pos": 5023867, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010060569.1", "url": "https://www.ensembl.org/id/ENSGALT00010060569.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010037328.1", "url": "https://www.ensembl.org/id/ENSGALP00010037328.1" } ] } }, { "isoform_ac": "A0A8V1A4D5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4E3/entry#A0A8V1A4D5-1", "sequence": { "sequence": "MVEPGQDLLLAALSESGISPNDLFDIDSPDVVLATPTPAVQQSVPLSALDLGLETEAPAAVKQEPETVSTPALLNVRQPPSTTTFVLNQINQLPTLGTTIVMTKTTPVTTTRQTITVAKIIQTSTTTRPSVAAPAVRNALTTAPSKDQIQLKDLLKNNSLNELMKLKPPPNIAQPVATAAKIIVVPPKVVNATRPADLSNGAVKKEASTKEVARIWINDVKMRSFSPTMKVPAVKEEEEPEEEDEEEMGHAETYAEYMPIKLKIGLRHPDPVVETSSLSSVTPPDVWYQTSISEETIDNGWLSALQLEAITYAAQQHETFLPNGDRAGFLIGDGAGVGKGRTIAGIIYENYLLGRKRAVWFSVSNDLKYDAERDLRDIGAKNILVHSLNKFKYGKISSKHNGSVKKGVIFATYSSLIGESQSGGKYKTRLKQLLHWCGEDFDGVIVFDECHKAKNLCPVGSSKPTKTGLAVLELQNKLPKARVVYASATGASEPRNMAYMNRLGIWGEGTPFREFSDFIQAVERRGVGAMEIVAMDMKLRGMYIARQLSFSGVTFKIDEVLLSQEYVKMYNKSVKLWVSARERFQQAADLIDAEQRMKKSMWGQFWSAHQRFFKYLCIASKVKRVVQLAREEIKNGKCVVIGLQSTGEARTLEALEEGGGELNDFVSTAKGVFQSLIEKHFPAPDRKKLFSLLGIDLTAQSNNNSPRDSPCKENKIKKRKGEEVSREAKKARKTGGLAGSSSDESESESDASDNEESDNESSRFLSSGDDDDFNPFRDESSEDDEDDPWLIRKEHKKVKEKKKKKSIDPDSIQSALLASGLGSKRPSCFTSTVGTTTSSTNASANSNTNSSFVTSQDAVERAQQMKKELLDKLEKLAEDLPPNTLDELIDELGGPENVAEMTGRKGRVVSNDDGSISYESRSELDVPVEILNITEKQRFMDGDKNIAIISEAASSGISLQADRRAKNQRRRVHMTLELPWSADRAIQQFGRTHRSNQVTAPEYVFLISELAGEQRFASIVAKRLESLGALTHGDRRATETRDLSRFNFDNKYGRNALEIVMKSIVNLDSPMVSPPPDFPGDFFKDVRQGLIGVGLINVEDRSGILTLDKDYNNIGKFLNRILGMEVHQQNALFQYFSDTLNAVIQNAKKNGRYDMGILDLGSGDEKVRKADVKKFLTPGYSTSGHVELYTISVERGMSWDEATKIWAEQTGPDDGFYLSLQIRNNKKTAILVKEVNPKKKLFLVYRPNTGKQLKLETCADLKKKYKKVPSEDALPHWLEQYNSSADTCTHAYWRGNCKKAGLGLVCEVGLRCRTYYVLCGSVLSVWTKVEGVLASVSGTNVKMQIVRLRTEDGQRIVGLIIPANCVSPLVNLLSTSDQSQQLAVQQQQIWQQHHPQSITNFNNA", "length": 1404, "header": "tr|A0A8V1A4D5-1|A0A8V1A4D5_CHICK Computationally mapped isoform of Protein strawberry notch homolog 1 OS=Gallus gallus OX=9031 GN=SBNO1 PE=3 SV=1 CANONICAL=A0A8V1A4E3-1" }, "locus": { "chromosome": "15", "start_pos": 5046183, "end_pos": 5023867, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010060574.1", "url": "https://www.ensembl.org/id/ENSGALT00010060574.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010037333.1", "url": "https://www.ensembl.org/id/ENSGALP00010037333.1" } ] } }, { "isoform_ac": "A0A8V1A4E3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4E3/entry#A0A8V1A4E3-1", "sequence": { "sequence": "MVEPGQDLLLAALSESGISPNDLFDIDSPDVVLATPTPAVQQSVPLSALDLGLETEAPAAVKQEPETVSTPALLNVRQPPSTTTFVLNQINQLPTLGTTIVMTKTTPVTTTRQTITVAKIIQTSTTTRPSVAAPAVRNALTTAPSKDQIQLKDLLKNNSLNELMKLKPPPNIAQPVATAATDLSNGAVKKEASTKEVARIWINDVKMRSFSPTMKVPAVKEEEEPEEEDEEEMGHAETYAEYMPIKLKIGLRHPDPVVETSSLSSVTPPDVWYQTSISEETIDNGWLSALQLEAITYAAQQHETFLPNGDRAGFLIGDGAGVGKGRTIAGIIYENYLLGRKRAVWFSVSNDLKYDAERDLRDIGAKNILVHSLNKFKYGKISSKHNGSVKKGVIFATYSSLIGESQSGGKYKTRLKQLLHWCGEDFDGVIVFDECHKAKNLCPVGSSKPTKTGLAVLELQNKLPKARVVYASATGASEPRNMAYMNRLGIWGEGTPFREFSDFIQAVERRGVGAMEIVAMDMKLRGMYIARQLSFSGVTFKIDEVLLSQEYVKMYNKSVKLWVSARERFQQAADLIDAEQRMKKSMWGQFWSAHQRFFKYLCIASKVKRVVQLAREEIKNGKCVVIGLQSTGEARTLEALEEGGGELNDFVSTAKGVFQSLIEKHFPAPDRKKLFSLLGIDLTAQSNNNSPRDSPCKENKIKKRKGEEVSREAKKARKTGGLAGSSSDESESESDASDNEESDNESSRFLSSGDDDDFNPFRDESSEDDEDDPWLIRKEHKKVKEKKKKKSIDPDSIQSALLASGLGSKRPSCFTSTVGTTTSSTNASANSNTNSSFVTSQDAVERAQQMKKELLDKLEKLAEDLPPNTLDELIDELGGPENVAEMTGRKGRVVSNDDGSISYESRSELDVPVEILNITEKQRFMDGDKNIAIISEAASSGISLQADRRAKNQRRRVHMTLELPWSADRAIQQFGRTHRSNQVTAPEYVFLISELAGEQRFASIVAKRLESLGALTHGDRRATETRDLSRFNFDNKYGRNALEIVMKSIVNLDSPMVSPPPDFPGDFFKDVRQGLIGVGLINVEDRSGILTLDKDYNNIGKFLNRILGMEVHQQNALFQYFSDTLNAVIQNAKKNGRYDMGILDLGSGDEKVRKADVKKFLTPGYSTSGHVELYTISVERGMSWDEATKIWAEQTGPDDGFYLSLQIRNNKKTAILVKEVNPKKKLFLVYRPNTGKQLKLETCADLKKKYKKVPSEDALPHWLEQYNSSADTCTHAYWRGNCKKAGLGLVCEVGLRCRTYYVLCGSVLSVWTKVEGVLASVSGTNVKMQIVRLRTEDGQRIVGLIIPANCVSPLVNLLSTSDQSQQLAVQQQQIWQQHHPQSITNFNNA", "length": 1389, "header": "tr|A0A8V1A4E3-1|A0A8V1A4E3_CHICK Isoform 1 of Protein strawberry notch homolog 1 OS=Gallus gallus OX=9031 GN=SBNO1 PE=3 SV=1 CANONICAL=A0A8V1A4E3-1" }, "locus": { "chromosome": "15", "start_pos": 5046183, "end_pos": 5023867, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010060579.1", "url": "https://www.ensembl.org/id/ENSGALT00010060579.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010037338.1", "url": "https://www.ensembl.org/id/ENSGALP00010037338.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 37, "start_aa": "Thr", "end_pos": 37, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr37", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:427694", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427694", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2MLK1-1", "protein_name": "Protein strawberry notch homolog 1", "gene_name": "Sbno1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MVEPGQDLLLAALSESGISPNDLFDVDGGDAGLATPTPPSVQQSMPLSALELGLETEAAVPVKQEPETMSTPALLNVRQQPPSTTTFVLNQINQLPTLGSTIVMTKTPPATTNRQTITLTKFIQTTANTRPSVSAPAVRNAMPPAPSKDQVQLKDLLKNNSLNELMKLKPPANIAQPVATAATDVSNGAVKKESSNKEVARIWINDMKMRSFSPTMKVPVVKEEDEPEEEDEEEMGHAETYAEYMPIKLKIGLRHPDAVVETSSLSSVTPPDVWYKTSISEETIDNGWLSALQLEAVTYAAQQHETFLPNGDRAGFLIGDGAGVGKGRTIAGIIYENYLLSRKRALWFSVSNDLKYDAERDLKDIGAKNILVHSLNKFKYGKISSKHNGSVKKGVIFATYSSLIGESQSGGKYKTRLKQLLHWCGDDFDGVIVFDECHKAKNLCPVGSSKPTKTGLAVLELQNKLPKARVVYASATGASEPRNMAYMNRLGIWGEGTPFREFSDFIQAVERRGVGAMEIVAMDMKLRGMYIARQLSFTGVTFKIEEVLLSQSYVKMYNKAVKLWVIARERFQQAADLIDAEQRMKKSMWGQFWSAHQRFFKYLCIASKVKRVVQLAREEIKNGKCVVIGLQSTGEARTLEALEEGGGELNDFVSTAKGVLQSLIEKHFPAPDRKKLYSLLGIDLTAPSNNSSPRDSPCKENKIKKRKGEEITREAKKARKVGGLTGSSSDDSGSESDVSDNEESDYESSKNMSSGDDDDFNPFRDESSEDNEDDPWLIRKEHKKSKDKKKKKSIDPDSIQSALLASGLGSKRPSFSSAPVISPAPNSAPANSNTNSNNSLITSQDAVERAQQMKKDLLDKLDKLAEDLPPNTLDELIDDLGGPENVAEMTGRKGRVVSNDDGSISYESRTEIDVPVEILNITEKQRFMDGKKNIAIISEAASSGISLQADRRAQNQRRRVHMTLELPWSADRAIQQFGRTHRSNQVTAPEYVFLISELAGEQRFASIVAKRLESLGALTHGDRRATESRDLSRFNFDNKYGRNALEIVMKSIVNLDSPMVSPPPDYPGEFFKDVRQGLIGVGLINVEDRSGILTLDKDYNNIGKFLNRILGMEVHQQNALFQYFADTLTAVVQNAKKNGRYDMGILDLGSGDEKVRKSDVKKFLTPGYSTSGHVELYTISVERGMSWEEATKIWAELTGPDDGFYLSLQIRNNKKTAILVKEVNPKKKLFLIYRPNTGKQLKLEIYADLKKKYKKVVSDDALVHWLDQYNSSADTCTHAYWRGNCKKASLGLVCEIGLRCRTYYVLCGSVLSVWTKVEGVLASVSGTNVKMQIVRLRTEDGQRIVGLIIPANCVSPLVNLLSTSDQSQQLAVQQKQLWQQHHPQSITNLSNS", "length": 1392 }, "evidence": [ { "id": "A0A8V1A4E3", "url": "https://omabrowser.org/oma/group/A0A8V1A4E3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A3KN83-1", "protein_name": "Protein strawberry notch homolog 1", "gene_name": "SBNO1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVEPGQDLLLAALSESGISPNDLFDIDGGDAGLATPMPTPSVQQSVPLSALELGLETEAAVPVKQEPETVPTPALLNVRQQPPSTTTFVLNQINHLPPLGSTIVMTKTPPVTTNRQTITLTKFIQTTASTRPSVSAPTVRNAMTSAPSKDQVQLKDLLKNNSLNELMKLKPPANIAQPVATAATDVSNGTVKKESSNKEGARMWINDMKMRSFSPTMKVPVVKEDDEPEEEDEEEMGHAETYAEYMPIKLKIGLRHPDAVVETSSLSSVTPPDVWYKTSISEETIDNGWLSALQLEAITYAAQQHETFLPNGDRAGFLIGDGAGVGKGRTIAGIIYENYLLSRKRALWFSVSNDLKYDAERDLRDIGAKNILVHSLNKFKYGKISSKHNGSVKKGVIFATYSSLIGESQSGGKYKTRLKQLLHWCGDDFDGVIVFDECHKAKNLCPVGSSKPTKTGLAVLELQNKLPKARVVYASATGASEPRNMAYMNRLGIWGEGTPFREFSDFIQAVERRGVGAMEIVAMDMKLRGMYIARQLSFTGVTFKIEEVLLSQSYVKMYNKAVKLWVIARERFQQAADLIDAEQRMKKSMWGQFWSAHQRFFKYLCIASKVKRVVQLAREEIKNGKCVVIGLQSTGEARTLEALEEGGGELNDFVSTAKGVLQSLIEKHFPAPDRKKLYSLLGIDLTAPSNNSSPRDSPCKENKIKKRKGEEITREAKKARKVGGLTGSSSDDSGSESDASDNEESDYESSKNMSSGDDDDFNPFLDESNEDDENDPWLIRKDHKKNKEKKKKKSIDPDSIQSALLASGLGSKRPSFSSTPVISPAPNSTPANSNTNSNSSLITSQDAVERAQQMKKDLLDKLEKLAEDLPPNTLDELIDELGGPENVAEMTGRKGRVVSNDDGSISYESRSELDVPVEILNITEKQRFMDGDKNIAIISEAASSGISLQADRRAKNQRRRVHMTLELPWSADRAIQQFGRTHRSNQVTAPEYVFLISELAGEQRFASIVAKRLESLGALTHGDRRATESRDLSRFNFDNKYGRNALEIVMKSIVNLDSPMVSPPPDYPGEFFKDVRQGLIGVGLINVEDRSGILTLDKDYNNIGKFLNRILGMEVHQQNALFQYFADTLTAVVQNAKKNGRYDMGILDLGSGDEKVRKSDVKKFLTPGYSTSGHVELYTISVERGMSWEEATKIWAELTGPDDGFYLSLQIRNNKKTAILVKEVNPKKKLFLVYRPNTGKQLKLEIYADLKKKYKKVVSDDALMHWLDQYNSSADTCTHAYWRGNCKKASLGLVCEIGLRCRTYYVLCGSVLSVWTKVEGVLASVSGTNVKMQIVRLRTEDGQRIVGLIIPANCVSPLVNLLSTSDQSQQLAVQQKQLWQQHHPQSITNLSNA", "length": 1393 }, "evidence": [ { "id": "A0A8V1A4E3", "url": "https://omabrowser.org/oma/group/A0A8V1A4E3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "E1BMP8-1", "protein_name": "Protein strawberry notch homolog 1", "gene_name": "SBNO1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MVEPGQDLLLAALSESGISPNDLFDIDGGDAGLATPTPTPPIQQSVPLSALELGLETEAAVPVKQEPETVPTPALLNVRQQPPSTTTFVLNQINQLPTLGSTIVMTKTPPVTTNRQTITLTKFIQTTANTRPSVSAPAVRNAMTSAPSKDQVQLKDLLKNNSLNELMKLKPPANIAQPVATAATDVSNGTVKKESSNKEVARIWINDMKMRSFSPTMKVPVVKEEDEPEEEDEEEMGHAETYAEYMPIKLKIGLRHPDAVVETSSLSSVTPPDVWYKTSISEETIDNGWLSALQLEAITYAAQQHETFLPNGDRAGFLIGDGAGVGKGRTIAGIIYENYLLSRKRALWFSVSNDLKYDAERDLRDIGAKNILVHSLNKFKYGKISSKHNGSVKKGVIFATYSSLIGESQSGGKYKTRLKQLLHWCGDDFDGVIVFDECHKAKNLCPVGSSKPTKTGLAVLELQNKLPKARVVYASATGASEPRNMAYMNRLGIWGEGTPFREFSDFIQAVERRGVGAMEIVAMDMKLRGMYIARQLSFTGVTFKIEEVLLSQSYVKMYNKAVKLWVIARERFQQAADLIDAEQRMKKSMWGQFWSAHQRFFKYLCIASKVKRVVQLAREEIKNGKCVVIGLQSTGEARTLEALEEGGGELNDFVSTAKGVLQSLIEKHFPAPDRKKLYSLLGIDLTAPSNSSSPRDSPCKENKTKKRKGEEITREAKKARKIGGLTGSSSDDSGSESDASDNEESDYESSKNMSSGDDDDFNPFRDESSEDDEDDPWLIRKDHKKNKDKKKRKSIDPDSIQSALLASGLGSKRPSFSSTPVISPAPNSAPANSNTNSNSSLITSQDAVERAQQMKKDLLDKLEKLAEDLPPNTLDELIDELGGPENVAEMTGRKGRVVSNDDGSISYESRSELDVPVEILNITEKQRFMDGDKNIAIISEAASSGISLQADRRAKNQRRRVHMTLELPWSADRAIQQFGRTHRSNQVTAPEYVFLISELAGEQRFASIVAKRLESLGALTHGDRRATESRDLSRFNFDNKYGRNALEIVMKSIVNLDSPMVSPPPDYPGEFFKDVRQGLIGVGLINVEDRSGILTLDKDYNNIGKFLNRILGMEVHQQNALFQYFADTLTAVVQNAKKNGRYDMGILDLGSGDEKVRKSDVKKFLTPGYSTSGHVELYTISVERGMSWEEATKIWAELTGPDDGFYLSLQIRNNKKTAILVKEVNPKKKLFLVYRPNTGKQLKLEIYADLKKKYKKVVSDDAVVHWLDQYNSSADTCTHAYWRGNCKKASLGLVCEIGLRCRTYYVLCGSVLSVWTKVEGVLASVSGTNVKMQIVRLRTEDGQRIVGLIIPANCVSPLINLLSTSDQSQQLAVQQKQLWQQRHPQSIASLSST", "length": 1393 }, "evidence": [ { "id": "A0A8V1A4E3", "url": "https://omabrowser.org/oma/group/A0A8V1A4E3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q5BJL5-1", "protein_name": "Protein strawberry notch homolog 1", "gene_name": "Sbno1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVEPGQDLLLAALSESGISPNDLFDVDGGDAGLATPTPPSVQQQQPPSTTTFVLNQINQLPTLGSTIVMTKTPPATTNRQTITLTKFIQTTANTRPSVSAPAVRNAIPPAPAKDQVQLKDLLKNNSLNELMKLKPPANIAQPVATAAADVSNGAVKKESSNKEVARVWINDMKMRSFSPTMKVPVVREEDEPEEEDEEEMGHAETYAEYMPIKLKIGLRHPDAVVETSSLSSVTPPDVWYKTSISEETIDNGWLSALQLEAVTYAAQQHETFLPNGDRAGFLIGDGAGVGKGRTIAGIIYENYLLSRKRALWFSVSNDLKYDAERDLRDIGAKNILVHSLNKFKYGKISSKHNGSVKKGVIFATYSSLIGESQSGGKYKTRLKQLLHWCGDDFDGVIVFDECHKAKNLCPVGSSKPTKTGLAVLELQNKLPKARVVYASATGASEPRNMAYMNRLGIWGEGTPFREFSDFIQAVERRGVGAMEIVAMDMKLRGMYIARQLSFTGVTFKIEEVLLSQSYVKMYNKAVKLWVIARERFQQAADLIDAEQRMKKSMWGQFWSAHQRFFKYLCIASKVKRVVQLAREEIKNGKCVVIGLQSTGEARTLEALEEGGGELNDFVSTAKGVLQSLIEKHFPAPDRKKLYSLLGIDLTAPSNNSSPRDSAKKARKIGGLTGSSSDDSGSESDVSDNEESDYESSKNMSSGDDDDFNPFRDDNSSLITSQDAVERAQQMKKDLLDKLEKLAEDLPPNTLDELIDELGGPENVAEMTGRKGRVVSNDDGSISYESRSELDVPVEILNITEKQRFMDGDKNIAIISEAASSGISLQADRRAKNQRRRVHMTLELPWSADRAIQQFGRTHRSNQVTAPEYVFLISELAGEQRFASIVAKRLESLGALTHGDRRATESRDLSRFNFDNKYGRNALEIVMKSIVNLDSPMVSPPPDYPGEFFKDVRQGLIGVGLINVEDRSGILTLDKDYNNIGKFLNRILGMEVHQQNALFQYFADTLTAVVQNAKKNGRYDMGILDLGSGDEKVRKSDVKKFLTPGYSTSGHVELYTISVERGMSWDEATKIWAELTGPDDGFYLSLQIRNNKKTAILVKEVNPKKKLFLIYRPNTGKQLKLEIYADLKKKYKKVVSDDALVHWLDQYNSSADTCTHAYWRGNCKKASLGLVCEIGLRCRTYYVLCGSVLSVWTKVEGVLASVSGTNVKMQIVRLRTEDGQRIVGLIIPANCVSPLVNLLSTSDQSQQLAVQQKQLWQQHHPQSITNLSNV", "length": 1269 }, "evidence": [ { "id": "A0A8V1A4E3", "url": "https://omabrowser.org/oma/group/A0A8V1A4E3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q689Z5-1", "protein_name": "Protein strawberry notch homolog 1", "gene_name": "Sbno1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVEPGQDLLLAALSESGISPNDLFDVDGGDAGLATPTPPSVQQSVPLSALELGLETEAAVPVKQEPEPMSTPALLNVRQPPSTTTFVLNQINQLPTLGSTIVMTKTPPATTNRQTITLTKFIQTTANTRPSVSAPAVRNAMPAAPSKDQVQLKDLLKNNSLNELMKLKPPANIAQPVATAATDVSNGAVKKESSNKEVARIWINDMKMRSFSPTMKVPVVKEEDEPEEEDEEEMGHAETYAEYMPIKLKIGLRHPDAVVETSSLSSVTPPDVWYKTSISEETIDNGWLSALQLEAVTYAAQQHETFLPNGDRAGFLIGDGAGVGKGRTIAGIIYENYLLSRKRALWFSVSNDLKYDAERDLRDIGAKNILVHSLNKFKYGKISSKHNGSVKKGVIFATYSSLIGESQSGGKYKTRLKQLLHWCGDDFDGVIVFDECHKAKNLCPVGSSKPTKTGLAVLELQNKLPKARVVYASATGASEPRNMAYMNRLGIWGEGTPFREFSDFIQAVERRGVGAMEIVAMDMKLRGMYIARQLSFTGVTFKIEEVLLSQSYVKMYNKAVKLWVIARERFQQAADLIDAEQRMKKSMWGQFWSAHQRFFKYLCIASKVKRVVQLAREEIKNGKCVVIGLQSTGEARTLEALEEGGGELNDFVSTAKGVLQSLIEKHFPAPDRKKLYSLLGIDLTAPSNNSSPRDSPCKENKIKKRKGEEITREAKKARKVGGLTGSSSDDSGSESVSDNDESDYESSKNMSSGDDDDFNPFRDESSEDNEDDPWLIRKDHKKSKDKKKKKSIDPDSIQSALLASGLGSKRPSFSSAPVISPASNSAPANSNSNSNSSLVTSQDAVERAQQMKKDLLDKLEKLAEDLPPNTLDELIDELGGPENVAEMTGRKGRVVSNDDGSISYESRSELDVPVEILNITEKQRFMDGDKNIAIISEAASSGISLQADRRAKNQRRRVHMTLELPWSADRAIQQFGRTHRSNQVTAPEYVFLISELAGEQRFASIVAKRLEGLGALTHGDRRATESRDLSRFNFDNKYGRNALEIVMKSIVNLDSPMVSPPPDYPGEFFKDVRQGLIGVGLINVEDRSGILTLDKDYNNIGKFLNRILGMEVHQQNALFQYFADTLTAVVQNAKKSGRYDMGILDLGSGDEKVRKSDVKKFLTPGYSTSGHVELYTISVERGMSWEEATKIWAELTGPDDGFYLSLQIRNNKKTAILVKEVNPKKKLFLIYRPNTGKQLKLEIYADLKKKYKKVVSDDALVHWLDQYNSSADTCTHAYWRGNCKKASLGLVCEIGLRCRTYYVLCGSVLSVWTKVEGVLASVSGTNVKMQIVRLRTEDGQRIVGLIIPANCVSPLVNLLSTSDQSQQLAVQQKQLWQQHHPQSITNLSNL", "length": 1390 }, "evidence": [ { "id": "A0A8V1A4E3", "url": "https://omabrowser.org/oma/group/A0A8V1A4E3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A4E3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4E3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A4E3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4E3" } ], "pmid": "" }, { "name": "positive regulation of signal transduction", "id": "GO:0009967", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009967", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A4E3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4E3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "chromatin DNA binding", "id": "GO:0031490", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031490", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A4E3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4E3" } ], "pmid": "" }, { "name": "histone binding", "id": "GO:0042393", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042393", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A4E3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4E3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1267, "end_pos": 1269, "annotation": "n_glycosylation_sequon" }, { "start_pos": 157, "end_pos": 159, "annotation": "n_glycosylation_sequon" }, { "start_pos": 386, "end_pos": 388, "annotation": "n_glycosylation_sequon" }, { "start_pos": 556, "end_pos": 558, "annotation": "n_glycosylation_sequon" }, { "start_pos": 688, "end_pos": 690, "annotation": "n_glycosylation_sequon" }, { "start_pos": 744, "end_pos": 746, "annotation": "n_glycosylation_sequon" }, { "start_pos": 826, "end_pos": 828, "annotation": "n_glycosylation_sequon" }, { "start_pos": 834, "end_pos": 836, "annotation": "n_glycosylation_sequon" }, { "start_pos": 917, "end_pos": 919, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1A4E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4E3" }, { "id": "PF25373", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25373" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SBNO alpha/beta", "eco_id": "ECO_0000259", "start_pos": 1182, "end_pos": 1296, "start_aa": "Met", "end_aa": "Arg", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1A4E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4E3" }, { "id": "PF13872", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13872" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Strawberry notch AAA", "eco_id": "ECO_0000259", "start_pos": 252, "end_pos": 557, "start_aa": "Arg", "end_aa": "Lys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1A4E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4E3" }, { "id": "PF13871", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13871" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Strawberry notch helicase C", "eco_id": "ECO_0000259", "start_pos": 868, "end_pos": 1144, "start_aa": "Asn", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 37 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1267, "end_pos": 1269 }, { "start_pos": 157, "end_pos": 159 }, { "start_pos": 386, "end_pos": 388 }, { "start_pos": 556, "end_pos": 558 }, { "start_pos": 688, "end_pos": 690 }, { "start_pos": 744, "end_pos": 746 }, { "start_pos": 826, "end_pos": 828 }, { "start_pos": 834, "end_pos": 836 }, { "start_pos": 917, "end_pos": 919 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A4C9-1", "uniprot_ac": "A0A8V1A4C9", "uniprot_id": "A0A8V1A4C9_CHICK", "mass": { "chemical_mass": 106201.0, "monoisotopic_mass": 106201.0 }, "refseq": { "ac": "XP_004937030", "name": "APC membrane recruitment protein 3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004937030" }, "gene_names": [ { "name": "AMER3", "type": "recommended", "evidence": [ { "id": "A0A8V1A4C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4C9" } ] }, { "name": "AMER3", "type": "synonym", "evidence": [ { "id": "XP_004937030", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004937030" } ] } ], "protein_names": [ { "name": "APC membrane recruitment protein 3", "type": "synonym", "evidence": [ { "id": "XP_004937030", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004937030" }, { "id": "A0A8V1A4C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4C9/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052540.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004937030.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004937030", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004937030" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A4C9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4C9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "AMER3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4C9", "locus": { "chromosome": "9", "start_pos": 2087052, "end_pos": 2157041, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010024264", "url": "https://www.ensembl.org/id/ENSGALG00010024264" } ] } } ], "crossref": [ { "id": "100859787", "url": "https://www.ncbi.nlm.nih.gov/gene/100859787", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019003", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019003", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:100859787", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100859787", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VMDNHDA", "url": "https://omabrowser.org/oma/group/VMDNHDA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A4C9", "url": "https://www.orthodb.org/?gene=A0A8V1A4C9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22237", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22237", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22237:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22237:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF09422", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09422", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004937030", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004937030", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1A4C9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4C9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A4C9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4C9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MELKRGKTFIKSSAQHERVPPAHTAPANRDEMGKDKRAALEGNQSVAQVQLACLATHKNYRFSSRAARSEAGENSLEKPSGTSYKLVRKSKTHDCVSEADKSEPCGPSSRACEEGFAAKGKGRLVNSVSFSGMSSSTSKKECVVNPSPPACSSQIIDYRNFVPQMPFVPAVAKTIPRKRISLKRSKKGLRDIFHIKKSKPESLTFLVEKDKNLSASGCKGEVPGRLTKSLFNTGETFAADCLSQDCSDNELQSDSSYDCCNALCEDVASLKSFDSLTGCGEIFADESSAHLELESSKEVLVRRSKHKESPVMGSFQGGVEQLASPGQNEAVEFAKFWDNINKSVRLHQSTLFDKKVLKVPGSDRGKAGGQAAAPATSPQTPPDKDGDNSKESSVETGTPKSDNQESISTSDEGYYDSFSPGQDDEVKEAQTPGVPGRFPRDSYSGDALYELFYDPNEVKINPVMDDDLCTSESVSEQAIEIPLSIYSFHVGAEENMASQPGIDIISQGFFHSTWKGKECLLKLCDTELSLTMGIINWLRKHAGIVSSPDSLQSPRSQPEKYNDSLITRSPSPEQKVSTEAQQEKKSEEESNSSHLGVFLDEGKAATQTSSENVAERDSCTQTGNVAPQGRAGSHHQDSPTAPGAAETTGASNCVPQLQANGDDTQPSSAEDKATMTDRHQTSGGEDPLTESLSRHSGSQSSENPLLNDNHDAESCYSYKTAATSPPDPLEREDRSEAVYHPLSICDELLQPLGLGHFQGYISPTPRESSAGIVQLLEHCMSRVASLKISYDNKHLEDNCIGNDMNGIICKMSQYKNKLLLQNECNCTDQKPEYCSIPCTNQYNYETGFQASSLYHLKQNGEEICSEDQKSRAKILDEVTRGKINFEYAQLNNKALSYLKDFTFELSAGDPAPAALSRPTFLPLPSTPTASPAAHSLPIAPQPWGAEQHSPGLWGCMAGGAALCPRPEAAAPDSAVTGSSHP", "length": 981, "header": "tr|A0A8V1A4C9-1|A0A8V1A4C9_CHICK Isoform 1 of APC membrane recruitment protein 3 OS=Gallus gallus OX=9031 GN=AMER3 PE=3 SV=1 CANONICAL=A0A8V1A4C9-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A4C9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4C9/entry#A0A8V1A4C9-1", "sequence": { "sequence": "MELKRGKTFIKSSAQHERVPPAHTAPANRDEMGKDKRAALEGNQSVAQVQLACLATHKNYRFSSRAARSEAGENSLEKPSGTSYKLVRKSKTHDCVSEADKSEPCGPSSRACEEGFAAKGKGRLVNSVSFSGMSSSTSKKECVVNPSPPACSSQIIDYRNFVPQMPFVPAVAKTIPRKRISLKRSKKGLRDIFHIKKSKPESLTFLVEKDKNLSASGCKGEVPGRLTKSLFNTGETFAADCLSQDCSDNELQSDSSYDCCNALCEDVASLKSFDSLTGCGEIFADESSAHLELESSKEVLVRRSKHKESPVMGSFQGGVEQLASPGQNEAVEFAKFWDNINKSVRLHQSTLFDKKVLKVPGSDRGKAGGQAAAPATSPQTPPDKDGDNSKESSVETGTPKSDNQESISTSDEGYYDSFSPGQDDEVKEAQTPGVPGRFPRDSYSGDALYELFYDPNEVKINPVMDDDLCTSESVSEQAIEIPLSIYSFHVGAEENMASQPGIDIISQGFFHSTWKGKECLLKLCDTELSLTMGIINWLRKHAGIVSSPDSLQSPRSQPEKYNDSLITRSPSPEQKVSTEAQQEKKSEEESNSSHLGVFLDEGKAATQTSSENVAERDSCTQTGNVAPQGRAGSHHQDSPTAPGAAETTGASNCVPQLQANGDDTQPSSAEDKATMTDRHQTSGGEDPLTESLSRHSGSQSSENPLLNDNHDAESCYSYKTAATSPPDPLEREDRSEAVYHPLSICDELLQPLGLGHFQGYISPTPRESSAGIVQLLEHCMSRVASLKISYDNKHLEDNCIGNDMNGIICKMSQYKNKLLLQNECNCTDQKPEYCSIPCTNQYNYETGFQASSLYHLKQNGEEICSEDQKSRAKILDEVTRGKINFEYAQLNNKALSYLKDFTFELSAGDPAPAALSRPTFLPLPSTPTASPAAHSLPIAPQPWGAEQHSPGLWGCMAGGAALCPRPEAAAPDSAVTGSSHP", "length": 981, "header": "tr|A0A8V1A4C9-1|A0A8V1A4C9_CHICK Isoform 1 of APC membrane recruitment protein 3 OS=Gallus gallus OX=9031 GN=AMER3 PE=3 SV=1 CANONICAL=A0A8V1A4C9-1" }, "locus": { "chromosome": "9", "start_pos": 2123578, "end_pos": 2121424, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010059185.1", "url": "https://www.ensembl.org/id/ENSGALT00010059185.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036121.1", "url": "https://www.ensembl.org/id/ENSGALP00010036121.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 764, "start_aa": "Thr", "end_pos": 764, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr764", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:100859787", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100859787", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "phosphatidylinositol-4,5-bisphosphate binding", "id": "GO:0005546", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005546", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A4C9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4C9" } ], "pmid": "" }, { "name": "beta-catenin binding", "id": "GO:0008013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008013", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A4C9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4C9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A4C9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4C9" } ], "pmid": "" }, { "name": "nuclear body", "id": "GO:0016604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016604", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A4C9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4C9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "Wnt signaling pathway", "id": "GO:0016055", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016055", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A4C9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4C9" } ], "pmid": "" }, { "name": "regulation of canonical Wnt signaling pathway", "id": "GO:0060828", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060828", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A4C9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4C9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 212, "end_pos": 214, "annotation": "n_glycosylation_sequon" }, { "start_pos": 341, "end_pos": 343, "annotation": "n_glycosylation_sequon" }, { "start_pos": 43, "end_pos": 45, "annotation": "n_glycosylation_sequon" }, { "start_pos": 562, "end_pos": 564, "annotation": "n_glycosylation_sequon" }, { "start_pos": 591, "end_pos": 593, "annotation": "n_glycosylation_sequon" }, { "start_pos": 825, "end_pos": 827, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 764 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 212, "end_pos": 214 }, { "start_pos": 341, "end_pos": 343 }, { "start_pos": 43, "end_pos": 45 }, { "start_pos": 562, "end_pos": 564 }, { "start_pos": 591, "end_pos": 593 }, { "start_pos": 825, "end_pos": 827 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", 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"end_pos": 4160768, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010025847", "url": "https://www.ensembl.org/id/ENSGALG00010025847" } ] } } ], "crossref": [ { "id": "A0A8V1A4D2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A4D2", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd13273", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13273", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "419893", "url": "https://www.ncbi.nlm.nih.gov/gene/419893", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", 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"MEHLLLAGSSRMVTASKFPTGGKFTCCKVLSHNLYTVLCIPHDPVALEEHFRDDDDGPVSSQGYMPYLNKYILDKVEEGAFVKENFDELCWTLTAKKNYKPDRNGNSVVSHQDAFKLWCLFNFLSEDKYPLIMVPDEVEYLLKKICTAMNVELNSCELDDCLSQEPQGQGGLTVWQFLDMVNSGRLLRGIEQEAISMAVEEVYQEVIEDVLKQGYLWKKGQLRRNWSERWFMLKPSALSYYMSEERKEKKGSITLDKHCCVEVLPDRDGKRCMFCVKTSSRTYEMSASDTRQRQEWTLAIQTAIRLQAEGKKSLHKDLKQKRREQREQREQRKAAKEEETQRLKQLQEEKERKLQELELLKEAQRQAEILLQEEEQRRRQQHEEMQRTLEIQLQEAEQARASMQAEMVLKEEEAERQRKRIMELEEMQERLQEALQQEVKARHDEESVRYAQARLLAEEEEKLKQLMKLKEEQEEYIIKTQLEKQVLKQEMENKNKCLEEAQKQLEEVRVNRQRVDQDVMAAQRKLRQASTNVKHWNVQMNRLMHPIEPGDKRTNMSGGGFAGYPPLMCRRDSSLKLKQKVEDKGSDPMRESSKENVSNGGSSSPLPSSDADTMATEASNQ", "length": 621, "header": "tr|A0A8V1A4D2-1|A0A8V1A4D2_CHICK Isoform 1 of DEF6 guanine nucleotide exchange factor OS=Gallus gallus OX=9031 GN=DEF6 PE=1 SV=1 CANONICAL=A0A8V1A4D2-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A4D2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4D2/entry#A0A8V1A4D2-1", "sequence": { "sequence": 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"tr|A0A8V1A6R2-1|A0A8V1A6R2_CHICK Computationally mapped isoform of DEF6 guanine nucleotide exchange factor OS=Gallus gallus OX=9031 GN=DEF6 PE=1 SV=1 CANONICAL=A0A8V1A4D2-1" }, "locus": { "chromosome": "26", "start_pos": 4160488, "end_pos": 4149730, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063013.1", "url": "https://www.ensembl.org/id/ENSGALT00010063013.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038906.1", "url": "https://www.ensembl.org/id/ENSGALP00010038906.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-8980692", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8980692", "resource": "Reactome", "description": "RHOA GTPase cycle" }, { "id": "R-GGA-9013148", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013148", "resource": "Reactome", "description": "CDC42 GTPase cycle" }, { "id": "R-GGA-9013149", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013149", "resource": "Reactome", "description": "RAC1 GTPase cycle" }, { "id": "R-GGA-9013404", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013404", "resource": "Reactome", "description": "RAC2 GTPase cycle" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZCK4-1", "protein_name": "IRF4-binding protein", "gene_name": "Def6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MATMIYVGIASEEVEAAPGLPLPGPLRASLCGLQPFAFPETGSWCQSRPWAGAGTSAMALRKELLKSIWYAFTALDVEKSGKVSKSQLKVLSHNLYTVLHIPHDPVALEEHFRDDDDGPVSSQGYMPYLNKYILDKVEEGAFVKEHFDELCWTLTAKKNYRVEGNGNSLLSNQDAFRLWCLFNFLSEDKYPLIMVPDEVEYLLKKLLGSLSLEMGLGELEELLAQDAQSAQTSGGLSVWQFLELFNSGRCLRGVGQDSLSMAIQEVYQELIQDVLKQGYLWKRGHLRRNWTERWFQLQPSCLCYFGSEECKEKRGTIPLDAHCCVEVLPDREGKRCMFCVKTASRTYEMSASDTRQRQEWTAAIQTAIRLQAEGKTSLHKDLKQKRREQREQRERRRAAKEEELLRLQQLQEEKERKLQELELLQEAQRQAERLLQEEEERRRSQHRELQQALEGQLREAEQARASMQAEMELKKEEAARQRQRIAELEEMQERLQEALQLEVKARRDEEAVRLAQTRLLEEEEEKLKQLMHLKEEQERYIERAQQEKQELQQEMALQSRSLQQAQQQLEEVRQNRQRADEDVEAAQRKLRQASTNVKHWNVQMNRLMHPIEPGDKRPTTSSSFTGFQAPPLARRDSSLKRLTRWGSQGNRTLSANSSEQKSLNGGDETPILALASQEEKLDAAPEN", "length": 687 }, "evidence": [ { "id": "A0A8V1A4D2", "url": "https://omabrowser.org/oma/group/A0A8V1A4D2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1RZ09-1", "protein_name": "IRF4-binding protein", "gene_name": "DEF6", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MALRKELLKSIWYAFTALDVEKSGKVSKSQLKVLSHNLYTVLHIPHDPVALEEHFRDDDDGPVSSQGYMPYLNKYILDKVEEGAFVKEHFDELCWTLTAKKNYQVDSNGNSMLSNQDAFRLWCLFNFLSEDKYPLIMVPDEVEYLLKKVLSSMSLEVGLGELEELLAQEAQAAQSSGGLSVWQFLELFNSGRCLRGVGRDTLSMAIHEVYQELIQDVLKQGYLWKRGHLRRNWAERWFQLQPSCLCYFGSEDCKEKRGTIPLDAQCCVEVLPDREGKRCMFCVKTASRTYEMSASDTRQRQEWTAAIQMAIRLQAEGKTSLHKDLKQKRREQREQRERRRAAKEEEMLRLQQLQEEKERKLQELELLQEAQRQAERLLQEEEERRRSQHRELQQALEGQLREAEQARASMQAEMELKKEEAARQQQRIQELEEMQQRLQEALHLEVKARRDEEAVRLAQTRLLEEEEEKLKQLLQLKEEQERYIEQAQQEKQELQQEMELQSRSLQQAQQQLEEVRQNRQRADEDVEAAQRKLRQASTNVKHWNVQMNRLMHPIEPGDKRPTTSSSFTGFQHPLLARRDSSLKRLTRWGSRDNRTPSPSSSEQQKSLNGGEEAPIAASTPQEDKRDPAPEN", "length": 631 }, "evidence": [ { "id": "A0A8V1A4D2", "url": "https://omabrowser.org/oma/group/A0A8V1A4D2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q7SYB5-1", "protein_name": "Differentially expressed in FDCP 6 homolog", "gene_name": "def6", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDLRSELLKSIWYAFTALDVEKSGKVSKSQLKVLSHNLYTVLKIPHEAAALEEHFRDDDDGPVSSQGYMPYLNKYILDKVVEGTFVKENVDELCWTLTAKKNYRPEGKSILPAKDAFRLWCLFIFLSEDRYPLVMIPDEVEYLLKKFCMAMSVELNYVELEDFISQDSVQQNGFTVWTFLEMMNSGKLTRGIAKETVSMAIEEVYREIVGDVLKEGYLWKKGQLRRNWTERWFTLRPSTLLYFTSEDRKDHKGNIQLDGNCCVEVLPDRDGKRCMFCLKTLTKTYELSASDTKQRQEWTTAIQTAIRLYVEGKTSLHKDLKLKRRDQREQREKRREAKEQELQRLRALQEERERKMAELELLKEAQRQAQAMLEQDEQRRRQQHEQLHQALEIQLKEAEEARASMQAEMALKEAEAEKQRTRIRELEAMQQRLEDALQQEIKARQDEEAFRYAQARLLAEEEEKMKALMGLREEQEEYIQRAQREKQELRQEMESKSRALEEAQRQLEETRANRYRVDQDVVAAQRKLRQASTNVKHWNVQMNRLMHPIGPGEKRSSGGSFSSFRIPSQKDPALRQKQKSEEQDEESKENMESRGGCEADRRLSTNGQMEIP", "length": 612 }, "evidence": [ { "id": "A0A8V1A4D2", "url": "https://omabrowser.org/oma/group/A0A8V1A4D2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8C2K1-1", "protein_name": "Differentially expressed in FDCP 6", "gene_name": "Def6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALRKELLKSIWYAFTALDVEKSGKVSKSQLKVLSHNLYTVLNIPHDPVALEEHFRDDDDGPVSSQGYMPYLNKYILDKVEEGAFVKEHFDELCWTLTAKKNYRADGIGSSPLSNQDAFRLWCLFNFLSEDKYPLIMVPDEVEYLLKKLLGSLSLEMGLGELEELLAQDAQSAQTAVGLSVWQFLELFNSGRCLRGVGRDSLSMAIQEVYQELIQDVLKQGYLWKRGHLRRNWAERWFQLQPSSLCYFGSEECKEKRGTIPLDAHCCVEVLPDREGKRCMFCVKTASRTYEMSASDTRQRQEWTAAIQTAIRLQAEGKTSLHKDLKQKRREQREQRERRRAAKEEELLRLQQLQEEKERKLQELELLQEAQRQAERLLQEEEERRRSQHKELQQALEGQLREAEQARASMQAEMELKKEEAARQRQRIAELEEMQERLQEALQLEVKARRDEEAVRLAQTRLLEEEEEKLKQLMHLKEEQERYIERAQQEKQELQQEMALQSRSLQHAQQQLEEVRQNRQRADEDVEAAQRKLRQASTNVKHWNVQMNRLMHPIEPGDKRPTTSSSFTGFQPPPLARRDSSLKRLTRWGSQGNRTLSVNSSEQKSLNGGDETPILALASQEEKLDPAPGN", "length": 630 }, "evidence": [ { "id": "A0A8V1A4D2", "url": "https://omabrowser.org/oma/group/A0A8V1A4D2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9H4E7-1", "protein_name": "Differentially expressed in FDCP 6 homolog", "gene_name": "DEF6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MALRKELLKSIWYAFTALDVEKSGKVSKSQLKVLSHNLYTVLHIPHDPVALEEHFRDDDDGPVSSQGYMPYLNKYILDKVEEGAFVKEHFDELCWTLTAKKNYRADSNGNSMLSNQDAFRLWCLFNFLSEDKYPLIMVPDEVEYLLKKVLSSMSLEVSLGELEELLAQEAQVAQTTGGLSVWQFLELFNSGRCLRGVGRDTLSMAIHEVYQELIQDVLKQGYLWKRGHLRRNWAERWFQLQPSCLCYFGSEECKEKRGIIPLDAHCCVEVLPDRDGKRCMFCVKTANRTYEMSASDTRQRQEWTAAIQMAIRLQAEGKTSLHKDLKQKRREQREQRERRRAAKEEELLRLQQLQEEKERKLQELELLQEAQRQAERLLQEEEERRRSQHRELQQALEGQLREAEQARASMQAEMELKEEEAARQRQRIKELEEMQQRLQEALQLEVKARRDEESVRIAQTRLLEEEEEKLKQLMQLKEEQERYIERAQQEKEELQQEMAQQSRSLQQAQQQLEEVRQNRQRADEDVEAAQRKLRQASTNVKHWNVQMNRLMHPIEPGDKRPVTSSSFSGFQPPLLAHRDSSLKRLTRWGSQGNRTPSPNSNEQQKSLNGGDEAPAPASTPQEDKLDPAPEN", "length": 631 }, "evidence": [ { "id": "A0A8V1A4D2", "url": "https://omabrowser.org/oma/group/A0A8V1A4D2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A4D2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4D2" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A4D2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4D2" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A4D2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4D2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "vesicle-mediated transport to the plasma membrane", "id": "GO:0098876", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098876", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A4D2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4D2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 225, "end_pos": 227, "annotation": "n_glycosylation_sequon" }, { "start_pos": 555, "end_pos": 557, "annotation": "n_glycosylation_sequon" }, { "start_pos": 596, "end_pos": 598, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1A4D2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4D2" }, { "id": "PS50003", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50003" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PH", "eco_id": "ECO_0000259", "start_pos": 209, "end_pos": 305, "start_aa": "Asp", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 225, "end_pos": 227 }, { "start_pos": 555, "end_pos": 557 }, { "start_pos": 596, "end_pos": 598 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A4E2-1", "uniprot_ac": "A0A8V1A4E2", "uniprot_id": "A0A8V1A4E2_CHICK", "mass": { "chemical_mass": 147406.0, "monoisotopic_mass": 147406.0 }, "refseq": {}, "gene_names": [ { "name": "PTCH2", "type": "recommended", "evidence": [ { "id": "A0A8V1A4E2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4E2" } ] } ], "protein_names": [ { "name": "Patched 2", "type": "synonym", "evidence": [ { "id": "A0A8V1A4E2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4E2/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A4E2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4E2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PTCH2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4E2", "locus": { "chromosome": "8", "start_pos": 20486669, "end_pos": 20501961, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010025862", "url": "https://www.ensembl.org/id/ENSGALG00010025862" } ] } } ], "crossref": [ { "id": "IPR000731", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000731", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004766", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004766", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR053958", "url": "https://www.ebi.ac.uk/interpro/entry/IPR053958", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A4E2", "url": "https://www.orthodb.org/?gene=A0A8V1A4E2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46022", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46022", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46022:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46022:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12349", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12349", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF27572", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27572", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1A4E2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4E2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A4E2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4E2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPAEPPRSAPPRAAAAALRKALPEGRGAPLWLRARFQALLFALGCRIQRHCGKVLFVGLLLFGALAVGLRVASVETDIEHLWVEAGSRVSQELRYTKEKLGEESVYTSQMLIQTPKREGENILTQEALQLHLEAALAASKVQVSLYGKSWDLNKICYKSGVPIIENGMIERMIEKLFPCVILTPLDCFWEGAKLQGGSAYLPGRPDIQWSNLDPLQLMEELGQFTSLEGFKELLDKAEVGQAYMERPCLDPRDPHCPSSAPNKQSQQSPDIPAELSGGCHGFSRKFMRWQEELILGGTTKDSQGKLLSAEALQTMFLLMSPRQLYEHFKDDYEIHDISWSEEKAGAILEAWQRKFVELAQDSIPPNATQNIHAFSTTTLNDIMKSFSDVSAIRVAGGYLLMLAYACVTMLRWDCSKSQGAVGLAGVLLVALSVASGLGLCSLLGISFNAATTQVLPFLALGIGVDDMFLLAHAFTETSQHIPFKERTGECLRRTGTSVALTSVSNMIAFFMAALVPIPALRAFSLQAAVVVVFNFAMVLFIFPAILSLDLYRREKRRLDILCCFYSPCSSRVIQIQPQELADANDNHASHPSPYGHPGVATSTQITTTVQAFTQCDPSGHHIVTVLPPTSQVCTSPAVLLPPADPLGSQVFTPSSSTRDLLAQLDEAKGGRECVPLPLCRWSLSDFAREKYAPLLLRTQTKVVVVVLFLALLGLSLYGTTMVHDGLYLTDIVPRDTKAHAFISAQFKYFSFYNMFIVTKGGFHYPGAQAALLSLHQAFSTVKYVVREGNHDLPKMWLHYFQDWLRGLQATFDRDWQAGRITHDSYRNGSEDGALAYKLLIQTGNKKEPFNFNQLTTRRLVDENGIIPPDTFYICLTVWASNDPLGFAASQANFYPPPPEWIHDKYDTTGENLRIPAAQPLEFAQFPFYLSGLRRTADFVEAIESVRAICQEAAQRHGVLSYPSGYPFLFWEQYIGLRHWFLLAISILLACTFLVCALLLLNPWTAGIIVSILAMMAVELFGIMGLMGIKLSAIPVVILIASVGIGVEFTVHVALGFLTAVGSRNVRSAAALEHTFAPVMDGAVSTLLGVLMLASSEFDFIMRYFFAVLTILTLLGLLNGLVLLPVLLSVIGPPSEASPVDNGPRLPPTEPVPPCLGPGGLYIRRAPAWPAAFTDTSDTECYGDGGGPGSPQGPFVVPPAPAHILLEAGKDPSFPRITVLKPYKDSPEVQGKKEQPVPQPAASLPFGEPCPTVLRDYPHPTALPRPGQPCSSSAWPASRAPLPAYSTHLQGPAGSYTTVTATASVTVALHPTLPGSYPSFGTETDSLEEPSAVPDSFEMQSLGRHGAGTRR", "length": 1350, "header": "tr|A0A8V1A4E2-1|A0A8V1A4E2_CHICK Isoform 1 of Patched 2 OS=Gallus gallus OX=9031 GN=PTCH2 PE=3 SV=1 CANONICAL=A0A8V1A4E2-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A4E2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4E2/entry#A0A8V1A4E2-1", "sequence": { "sequence": "MPAEPPRSAPPRAAAAALRKALPEGRGAPLWLRARFQALLFALGCRIQRHCGKVLFVGLLLFGALAVGLRVASVETDIEHLWVEAGSRVSQELRYTKEKLGEESVYTSQMLIQTPKREGENILTQEALQLHLEAALAASKVQVSLYGKSWDLNKICYKSGVPIIENGMIERMIEKLFPCVILTPLDCFWEGAKLQGGSAYLPGRPDIQWSNLDPLQLMEELGQFTSLEGFKELLDKAEVGQAYMERPCLDPRDPHCPSSAPNKQSQQSPDIPAELSGGCHGFSRKFMRWQEELILGGTTKDSQGKLLSAEALQTMFLLMSPRQLYEHFKDDYEIHDISWSEEKAGAILEAWQRKFVELAQDSIPPNATQNIHAFSTTTLNDIMKSFSDVSAIRVAGGYLLMLAYACVTMLRWDCSKSQGAVGLAGVLLVALSVASGLGLCSLLGISFNAATTQVLPFLALGIGVDDMFLLAHAFTETSQHIPFKERTGECLRRTGTSVALTSVSNMIAFFMAALVPIPALRAFSLQAAVVVVFNFAMVLFIFPAILSLDLYRREKRRLDILCCFYSPCSSRVIQIQPQELADANDNHASHPSPYGHPGVATSTQITTTVQAFTQCDPSGHHIVTVLPPTSQVCTSPAVLLPPADPLGSQVFTPSSSTRDLLAQLDEAKGGRECVPLPLCRWSLSDFAREKYAPLLLRTQTKVVVVVLFLALLGLSLYGTTMVHDGLYLTDIVPRDTKAHAFISAQFKYFSFYNMFIVTKGGFHYPGAQAALLSLHQAFSTVKYVVREGNHDLPKMWLHYFQDWLRGLQATFDRDWQAGRITHDSYRNGSEDGALAYKLLIQTGNKKEPFNFNQLTTRRLVDENGIIPPDTFYICLTVWASNDPLGFAASQANFYPPPPEWIHDKYDTTGENLRIPAAQPLEFAQFPFYLSGLRRTADFVEAIESVRAICQEAAQRHGVLSYPSGYPFLFWEQYIGLRHWFLLAISILLACTFLVCALLLLNPWTAGIIVSILAMMAVELFGIMGLMGIKLSAIPVVILIASVGIGVEFTVHVALGFLTAVGSRNVRSAAALEHTFAPVMDGAVSTLLGVLMLASSEFDFIMRYFFAVLTILTLLGLLNGLVLLPVLLSVIGPPSEASPVDNGPRLPPTEPVPPCLGPGGLYIRRAPAWPAAFTDTSDTECYGDGGGPGSPQGPFVVPPAPAHILLEAGKDPSFPRITVLKPYKDSPEVQGKKEQPVPQPAASLPFGEPCPTVLRDYPHPTALPRPGQPCSSSAWPASRAPLPAYSTHLQGPAGSYTTVTATASVTVALHPTLPGSYPSFGTETDSLEEPSAVPDSFEMQSLGRHGAGTRR", 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"tr|A0A8V1A4E6-1|A0A8V1A4E6_CHICK Isoform 1 of WD repeat domain 82 OS=Gallus gallus OX=9031 GN=WDR82 PE=3 SV=1 CANONICAL=A0A8V1A4E6-1" }, "locus": { "chromosome": "12", "start_pos": 3171932, "end_pos": 3155087, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066555.1", "url": "https://www.ensembl.org/id/ENSGALT00010066555.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040764.1", "url": "https://www.ensembl.org/id/ENSGALP00010040764.1" } ] } }, { "isoform_ac": "A0A8V1AC11-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4E6/entry#A0A8V1AC11-1", "sequence": { "sequence": "MKLTDNVLRSFRVAKVFRENSDKINCFDFSPNGETVISSSDDDSIVLYDCQEGNLGIESQPSGSLRAYRLASLPR", "length": 75, "header": "tr|A0A8V1AC11-1|A0A8V1AC11_CHICK Computationally mapped isoform of WD repeat domain 82 OS=Gallus gallus OX=9031 GN=WDR82 PE=3 SV=1 CANONICAL=A0A8V1A4E6-1" }, "locus": { "chromosome": "12", "start_pos": 3171932, "end_pos": 3171603, "strand": "+", "evidence": [ { 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"Ensembl Transcript", "id": "ENSGALT00010066556.1", "url": "https://www.ensembl.org/id/ENSGALT00010066556.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040765.1", "url": "https://www.ensembl.org/id/ENSGALP00010040765.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-9930044", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9930044", "resource": "Reactome", "description": "Nuclear RNA decay" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 8, "go_terms": [ { "name": "negative regulation of DNA-templated transcription, elongation", "id": "GO:0032785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032785", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A4E6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4E6" } ], "pmid": "" }, { "name": "DNA-templated transcription termination", "id": "GO:0006353", "url": 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"MDLTVNLTSFSLSTPSSLEPNRSLGTEDLRPSRPFLSIFRVLVLTLLGFLAAATFAWNLLVLATILRVRTFHRVPHNLVASMAISDVLVAALVMPLSLVHELSGRRWRLGRRLCQLWIACDVLCCTASIWNVTAIALDRYWSITRHLEYTLRARKRVSNVMIALTWALSAVISLAPLLFGWGETYSELSEVCQVSREPSYTVFSTVGAFYLPLCVVLFVYWKIYKAAKFRVGSRKTNSVSPVPEAVEVKNATQEPQMVFTVRHATVTFQTEGDTWREQKEQRAALMVGILIGVFVLCWFPFFVTELISPLCSWDIPAIWKSIFLWLGYSNSFFNPLIYTAFNRSYSSAFKVFFSKQQ", "length": 357 }, "evidence": [ { "id": "A0A8V1A4I2", "url": "https://omabrowser.org/oma/group/A0A8V1A4I2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "E1BGY8-1", "protein_name": "5-hydroxytryptamine receptor 5A", "gene_name": "HTR5A", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MDPPANLSYFTLSTPAPGEANRSSFDAADPRPRLPLLSVFGVLVLTLLGFLVAATFAWNLLVLATILRVRTFHRVPHNLMASMAISDVLVAALVMPLSLVHELSGRRWQLGRRLCQLWIACDVLCCTASIWNVTAIALDRYWSITRHLEYTLRARRRVSNVMIALTWALSAVISLAPLLFGWGETYSEGSEECQVSREPSYTVFSTVGAFYLPLGVVLFVYWKIYKAAKLRVGPRKTNSVSPISETVQGKGAAQRPEMVLAARRAKVTFQADGDAWREQKEQRAALMVGILIGVFVLCWIPFFTAELLRPLCACDVPATWKSVFLWLGYSNSFFNPLIYTAFNKNYNSAFKNFFSRHR", "length": 358 }, "evidence": [ { "id": "A0A8V1A4I2", "url": "https://omabrowser.org/oma/group/A0A8V1A4I2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P30966-1", "protein_name": "5-hydroxytryptamine receptor 5A", "gene_name": "Htr5a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": 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} ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A4I7-1", "uniprot_ac": "A0A8V1A4I7", "uniprot_id": "A0A8V1A4I7_CHICK", "mass": { "chemical_mass": 58740.0, "monoisotopic_mass": 58740.0 }, "refseq": {}, "gene_names": [ { "name": "FANCE", "type": "recommended", "evidence": [ { "id": "A0A8V1A4I7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4I7" } ] } ], "protein_names": [ { "name": "FA complementation group E", "type": "synonym", "evidence": [ { "id": "A0A8V1A4I7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4I7/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A4I7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4I7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FANCE", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4I7", "locus": { "chromosome": "26", "start_pos": 4120667, "end_pos": 4125211, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027520", "url": "https://www.ensembl.org/id/ENSGALG00010027520" } ] } } ], "crossref": [ { "id": "A0A8V1A4I7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A4I7", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd07439", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07439", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR021025", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021025", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039685", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039685", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A4I7", "url": "https://www.orthodb.org/?gene=A0A8V1A4I7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR32094", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR32094", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR32094:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR32094:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF11510", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11510", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-6783310", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6783310", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9833482", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9833482", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1A4I7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4I7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A4I7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4I7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MWRCPIAQLRPSAGRCSARFSCGRMELPWLRLLAKPCRLLLLALSSGPAGTLAALRALQRLQAQEGPGHAFPWRSFVGALCAEEPTLDGPDGALAVKPRLLLLPVLCQRNLFSLLHAVAAVVPTDCLRQLLTAAGQDPQPDPWVHALGVLLLRGEERSSPPPPPLTASGQQQLKCLCQKIAQSEAEGRRKLKWCFSRQDGDAAGCVLPLGKRKKVLEESLEFSEEREGKRPLLEDAVFELQGGLDGTAGVGEEVPGETSGDGSAQSLAGAALESPQQNADKEPSRISRPEVAVEVQSFIQMHGPRLKMLLLQEASHAEPSIPPELHILNSCSPSQLEGLCSFLQLSTCPEQLLGRFCSWLLALTPDLSYTSAAVLAEQLFLTRVLSLSQPPSRHLMAALISFCSKYSEPFCQVLVAPVLREPGQGAEQTKLVCELVEECLEPDYVRMVLGQVLAVPLTEKLLPVVLAVLGRQEPLPSELFDLLVLTLCRQAPAFATSLSYAKLVTAVLTTYSSQLSPSHRSRLAAALDGSNAALRRSLQAALGR", "length": 544, "header": "tr|A0A8V1A4I7-1|A0A8V1A4I7_CHICK Isoform 1 of FA complementation group E OS=Gallus gallus OX=9031 GN=FANCE PE=4 SV=1 CANONICAL=A0A8V1A4I7-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A4I7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4I7/entry#A0A8V1A4I7-1", "sequence": { "sequence": 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"id": "ENSGALG00010027531", "url": "https://www.ensembl.org/id/ENSGALG00010027531" } ] } } ], "crossref": [ { "id": "A0A8V1A4K1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A4K1", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR014806", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014806", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016135", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016135", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A4K1", "url": "https://www.orthodb.org/?gene=A0A8V1A4K1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12921", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12921", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12921:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12921:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08694", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08694", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1A4K1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4K1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A4K1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4K1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "AVAAVPLLRTAAGPRDRERWAERLKEEYRALIQYVEHNKASDNDWFRLESNAEGTRWSGRCWHIHELLKYEFAIEFEVSVAEGGGEKLLQPLPQCPQLSLCVPPPPPPDPGDVPQHCS", "length": 118, "header": "tr|A0A8V1A4K1-1|A0A8V1A4K1_CHICK Isoform 1 of Ubiquitin-fold modifier-conjugating enzyme 1 OS=Gallus gallus OX=9031 GN=UFC1 PE=3 SV=1 CANONICAL=A0A8V1A4K1-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A4K1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4K1/entry#A0A8V1A4K1-1", "sequence": { "sequence": "AVAAVPLLRTAAGPRDRERWAERLKEEYRALIQYVEHNKASDNDWFRLESNAEGTRWSGRCWHIHELLKYEFAIEFEVSVAEGGGEKLLQPLPQCPQLSLCVPPPPPPDPGDVPQHCS", "length": 118, "header": "tr|A0A8V1A4K1-1|A0A8V1A4K1_CHICK Isoform 1 of Ubiquitin-fold modifier-conjugating enzyme 1 OS=Gallus gallus OX=9031 GN=UFC1 PE=3 SV=1 CANONICAL=A0A8V1A4K1-1" }, "locus": { "chromosome": "25", "start_pos": 2501235, "end_pos": 2500341, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066681.1", "url": "https://www.ensembl.org/id/ENSGALT00010066681.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040826.1", "url": "https://www.ensembl.org/id/ENSGALP00010040826.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "brain development", "id": "GO:0007420", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007420", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A4K1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4K1" } ], "pmid": "" }, { "name": "reticulophagy", "id": "GO:0061709", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061709", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A4K1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4K1" } ], "pmid": "" }, { "name": "protein K69-linked ufmylation", "id": "GO:1990592", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990592", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A4K1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4K1" } ], "pmid": "" }, { "name": "regulation of type II interferon production", "id": "GO:0032649", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032649", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A4K1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4K1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "UFM1 conjugating enzyme activity", "id": "GO:0061657", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061657", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A4K1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4K1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", 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"categories": [ "Protein Classification" ] }, { "id": "PTHR11905:SF120", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11905:SF120", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00200", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00200", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01421", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01421", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08516", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08516", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-2534343", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2534343", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1A4K2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4K2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A4K2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4K2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "VCLSLSSKKTALEQLKHSVPCNTQLTPRQFQPWGRTRYLELMVVVDKEGFDTFGTSITNVTLEVIEIINLVDGLFSSVRLRVLLTVLEIWTEKNPISITKNITQVLHSFNRWRIQHGPAHIMHDVGCLFASACNRQHSSAVVSFAKHTYIETAVHVAHELGYVLGMEHDDEHCRCGNASKCIMNPKSTVSYGFSNCSTKYYFDFITSGQGQCLNNIPSSIARFVPQRCGNGVLEDREECDCGTEEQCKSDPCCDNTCRKKEGAICTSGQCCKDCKPLPEGVVCRKSTNPCDLPEYCNGTSEHCPEDVAKQDGTRCAADGYCYSGKCRSRTLQCKDIFGEKAQAAPLQCFEELNTKGDRFGNCWGDGTATKFQKCKLENVLCGRVQCTNIRHLPQTEDHSTIIQTPVGDTWCWGTEYHVGLDTSDAGVIKDGTRCGEKKICINRTFLMVCTGSHGCE", "length": 456, "header": "tr|A0A8V1A4K2-1|A0A8V1A4K2_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1A4K2-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A4K2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4K2/entry#A0A8V1A4K2-1", "sequence": { "sequence": "VCLSLSSKKTALEQLKHSVPCNTQLTPRQFQPWGRTRYLELMVVVDKEGFDTFGTSITNVTLEVIEIINLVDGLFSSVRLRVLLTVLEIWTEKNPISITKNITQVLHSFNRWRIQHGPAHIMHDVGCLFASACNRQHSSAVVSFAKHTYIETAVHVAHELGYVLGMEHDDEHCRCGNASKCIMNPKSTVSYGFSNCSTKYYFDFITSGQGQCLNNIPSSIARFVPQRCGNGVLEDREECDCGTEEQCKSDPCCDNTCRKKEGAICTSGQCCKDCKPLPEGVVCRKSTNPCDLPEYCNGTSEHCPEDVAKQDGTRCAADGYCYSGKCRSRTLQCKDIFGEKAQAAPLQCFEELNTKGDRFGNCWGDGTATKFQKCKLENVLCGRVQCTNIRHLPQTEDHSTIIQTPVGDTWCWGTEYHVGLDTSDAGVIKDGTRCGEKKICINRTFLMVCTGSHGCE", "length": 456, "header": "tr|A0A8V1A4K2-1|A0A8V1A4K2_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1A4K2-1" }, "locus": { "chromosome": "15", "start_pos": 6259265, "end_pos": 6256308, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063138.1", "url": "https://www.ensembl.org/id/ENSGALT00010063138.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038975.1", "url": "https://www.ensembl.org/id/ENSGALP00010038975.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-2534343", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2534343", "resource": "Reactome", "description": "Interaction With Cumulus Cells And The Zona Pellucida" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "metalloendopeptidase activity", "id": "GO:0004222", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004222", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A4K2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4K2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A4K2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4K2" } ], "pmid": "" }, { "name": "external side of plasma membrane", "id": "GO:0009897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009897", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A4K2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4K2" } ], "pmid": "" }, { "name": "sperm head plasma membrane", "id": "GO:1990913", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990913", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A4K2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4K2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A4K2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4K2" } ], "pmid": "" }, { "name": "male gonad development", "id": "GO:0008584", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008584", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A4K2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4K2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 101, "end_pos": 103, "annotation": "n_glycosylation_sequon" }, { "start_pos": 177, "end_pos": 179, "annotation": "n_glycosylation_sequon" }, { "start_pos": 195, "end_pos": 197, "annotation": "n_glycosylation_sequon" }, { "start_pos": 297, "end_pos": 299, "annotation": "n_glycosylation_sequon" }, { "start_pos": 442, "end_pos": 444, "annotation": "n_glycosylation_sequon" }, { "start_pos": 59, "end_pos": 61, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1A4K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4K2" }, { "id": "PS50214", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50214" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Disintegrin", "eco_id": "ECO_0000259", "start_pos": 225, "end_pos": 311, "start_aa": "Pro", "end_aa": "Asp", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1A4K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4K2" }, { "id": "PS50215", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50215" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Peptidase M12B", "eco_id": "ECO_0000259", "start_pos": 37, "end_pos": 217, "start_aa": "Arg", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 101, "end_pos": 103 }, { "start_pos": 177, "end_pos": 179 }, { "start_pos": 195, "end_pos": 197 }, { "start_pos": 297, "end_pos": 299 }, { "start_pos": 442, "end_pos": 444 }, { "start_pos": 59, "end_pos": 61 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A4L3-1", "uniprot_ac": "A0A8V1A4L3", "uniprot_id": "A0A8V1A4L3_CHICK", "mass": { "chemical_mass": 74025.0, "monoisotopic_mass": 74025.0 }, "refseq": { "ac": "NP_001025740", "name": "HEAT repeat-containing protein 3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025740" }, "gene_names": [ { "name": "HEATR3", "type": "recommended", "evidence": [ { "id": "A0A8V1A4L3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4L3" } ] }, { "name": "HEATR3", "type": "synonym", "evidence": [ { "id": "NP_001025740", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025740" } ] } ], "protein_names": [ { "name": "HEAT repeat containing 3", "type": "synonym", "evidence": [ { "id": "A0A8V1A4L3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4L3/entry#names_and_taxonomy" } ] }, { "name": "HEAT repeat-containing protein 3", "type": "synonym", "evidence": [ { "id": "NP_001025740", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025740" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ720710.1, SRR13267653.10100.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000248.1. On Sep 23, 2021 this sequence version replaced NP_001025740.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001025740", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025740" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A4L3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4L3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "HEATR3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4L3", "locus": { "chromosome": "11", "start_pos": 6278671, "end_pos": 6296711, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010025910", "url": "https://www.ensembl.org/id/ENSGALG00010025910" } ] } } ], "crossref": [ { "id": "A0A8V1A4L3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A4L3", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd13394", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13394", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "415734", "url": "https://www.ncbi.nlm.nih.gov/gene/415734", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000225", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000225", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052616", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052616", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:415734", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415734", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ENELHAD", "url": "https://omabrowser.org/oma/group/ENELHAD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A4L3", "url": "https://www.orthodb.org/?gene=A0A8V1A4L3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AC01", "url": "https://www.orthodb.org/?gene=A0A8V1AC01", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13347", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13347", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13347:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13347:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF25567", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25567", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001025740", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025740", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1A4L3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4L3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A4L3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4L3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AC01", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC01", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AC01-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC01-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGKSRARRFRRVPFSPTGSEPRREVEDGPEEEPAAELLQKLQHPSAEVREYACASISRLLQQQHVIPAFLQRDVVRCLGPMLLDHSLAVRETAAGALRNLSACGGFEVCDDMVTQDIMTPLVALLKECSNGLDANQLSPKKRREVNKNYVEDIANEAINLLWNVCECNSTAVSIFNKEGCLEAVLHYIKKFSTNVDLAISVANCLQAVTEDNPDLLSSFSASTHQVLETVMMCPESTMKHILLRTLIAGTIWNIKETIPPGSLGNMVNAILKIFSESLAIDAGETIIHMNEAEKNRLKPAAGAETEESEIDVTDNCALSEDDGMEEVSKGKGSGEHDISDLLPSDKWELKEVTALLMAQQTALEIIVNMCCSEDPSDDEWEELSSSDESDLFMENSYSEGSGLLMSPLCLSAEVHSAFLNNLIPKKILEKTAFPNSVALDICVHNPSWKPLIKKMNTVQCRALTCLHSILLVSDVDCLGGASALQSLAQHLSQLIFSKTELPEDTEFLEAITSALRALLQTMASKNISQCMTPEQLLALCEASIHSSNASVRVNVVSILGISGSVLAKVQDTAETLKMIGKFLLEVAMKESSLVVAGEALDALFDVFADGKEAEKAAVQMKLLPALKEFQPMFKMRIRKEGKGQYSTDQLCVLDNVKMNLRRFIAYQETLGKNPT", "length": 675, "header": "tr|A0A8V1A4L3-1|A0A8V1A4L3_CHICK Isoform 1 of HEAT repeat containing 3 OS=Gallus gallus OX=9031 GN=HEATR3 PE=3 SV=1 CANONICAL=A0A8V1A4L3-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A4L3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4L3/entry#A0A8V1A4L3-1", "sequence": { "sequence": "MGKSRARRFRRVPFSPTGSEPRREVEDGPEEEPAAELLQKLQHPSAEVREYACASISRLLQQQHVIPAFLQRDVVRCLGPMLLDHSLAVRETAAGALRNLSACGGFEVCDDMVTQDIMTPLVALLKECSNGLDANQLSPKKRREVNKNYVEDIANEAINLLWNVCECNSTAVSIFNKEGCLEAVLHYIKKFSTNVDLAISVANCLQAVTEDNPDLLSSFSASTHQVLETVMMCPESTMKHILLRTLIAGTIWNIKETIPPGSLGNMVNAILKIFSESLAIDAGETIIHMNEAEKNRLKPAAGAETEESEIDVTDNCALSEDDGMEEVSKGKGSGEHDISDLLPSDKWELKEVTALLMAQQTALEIIVNMCCSEDPSDDEWEELSSSDESDLFMENSYSEGSGLLMSPLCLSAEVHSAFLNNLIPKKILEKTAFPNSVALDICVHNPSWKPLIKKMNTVQCRALTCLHSILLVSDVDCLGGASALQSLAQHLSQLIFSKTELPEDTEFLEAITSALRALLQTMASKNISQCMTPEQLLALCEASIHSSNASVRVNVVSILGISGSVLAKVQDTAETLKMIGKFLLEVAMKESSLVVAGEALDALFDVFADGKEAEKAAVQMKLLPALKEFQPMFKMRIRKEGKGQYSTDQLCVLDNVKMNLRRFIAYQETLGKNPT", "length": 675, "header": "tr|A0A8V1A4L3-1|A0A8V1A4L3_CHICK Isoform 1 of HEAT repeat containing 3 OS=Gallus gallus OX=9031 GN=HEATR3 PE=3 SV=1 CANONICAL=A0A8V1A4L3-1" }, "locus": { "chromosome": "11", "start_pos": 6296655, "end_pos": 6279422, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063162.1", "url": "https://www.ensembl.org/id/ENSGALT00010063162.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038985.1", "url": "https://www.ensembl.org/id/ENSGALP00010038985.1" } ] } }, { "isoform_ac": "A0A8V1AC01-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4L3/entry#A0A8V1AC01-1", "sequence": { "sequence": "MGKSRARRFRRVPFSPTGSEPRREVEDGPEEEPAAELLQKLQHPSAEVREYACASISRLLQQQHVIPAFLQRDVVRCLGPMLLDHSLAVRETAAGALRNLSACGGFEVCDDMVTQDIMTPLVALLKECSNGLDANQLSPKKRREVNKNYVEDIANEAINLLWNVCECNSTAVSIFNKEGCLEAVLHYIKKFSTNVDLAISVANCLQAVTEDNPDLLSSFSASTHQVLETVMMCPESTMKHILLRTLIAGTIWNIKETIPPGSLGNMVNAILKIFSESLAIDAGETIIHMNEAEKNRLKPAAGAETEESEIDVTDNCALSEDDGMEEVSKGKGSGEHDISDLLPSDKWELKEVTALLMAQQTALEIIVNMCCNPSDDEWEELSSSDESDLFMENSYSEGSGLLMSPLCLSAEVHSAFLNNLIPKKILEKTAFPNSVALDICVHNPSWKPLIKKMNTVQCRALTCLHSILLVSDVDCLGGASALQSLAQHLSQLIFSKTELPEDTEFLEAITSALRALLQTMASKNISQCMTPEQLLALCEASIHSSNASVRVNVVSILGISGSVLAKVQDTAETLKMIGKFLLEVAMKESSLVVAGEALDALFDVFADGKEAEKAAVQMKLLPALKEFQPMFKMRIRKEGKGQYSTDQLCVLDNVKMNLRRFIAYQETLGKNPT", "length": 673, "header": "tr|A0A8V1AC01-1|A0A8V1AC01_CHICK Computationally mapped isoform of HEAT repeat containing 3 OS=Gallus gallus OX=9031 GN=HEATR3 PE=3 SV=1 CANONICAL=A0A8V1A4L3-1" }, "locus": { "chromosome": "11", "start_pos": 6296655, "end_pos": 6279422, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063169.1", "url": "https://www.ensembl.org/id/ENSGALT00010063169.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038989.1", "url": "https://www.ensembl.org/id/ENSGALP00010038989.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:415734", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415734", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZV81-1", "protein_name": "HEAT repeat-containing protein 3", "gene_name": "Heatr3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGKSRTKRFKRPQFSPVGSCQAEAAATANGTGDEEDDGLAAELLEKLQHPSAEVRECACAGLARLVQQRPALPDLARRDAVRRLGPLLLDSSLAVRETAAGALRNLSACGGFDVCDDMVAKDIMTPLVALLRECSSGLDSNEMSPQEKADKKRNSIESIANEAVNVLWNVCECSSRAVSIFNKEGCLEIVLQYLRRFPTSIDLAVSVAYCLQTVTEDNPELLKSFDGTALRVLESALLCPVTSMEYILLKTLVAGTIWNLKDIIPSKSQAEIINAILNTLSEVLGVNAGDTVIQMKEAETQRLKDAAESEDILANANGDGEMEFQDDEMEEIPHKRKLRRKTFISDLLPSTDKELREAMALLTAQQTALEVIVNMCCSEDPSDDEWEELSSSDESEAFMENSFNECSGQLMSPLCLSHEIHSALTNCLIPKKVFEKTSSPNSDAVDICSKNPTWKPLIRKMSTIQCRALMCLQSLVSLLDIDHLGGAPALQTLAQHLSQLLFSQPDFAKHADFLEAISSALRALLQTMASKNIPQCMTPEQLMTLCREGIHSSSIGVRVNVVSILGITGSVLAKEDGTLETLKTIGCFLLEVTTKDPSLVVAGEALDALFDVFADGEEAEKASVQIKLLAALKEFQPVFKMKMRKEGRARYSPDQLCVLDNVKMNLRRFIAYQETVEKRLTS", "length": 682 }, "evidence": [ { "id": "A0A8V1A4L3", "url": "https://omabrowser.org/oma/group/A0A8V1A4L3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7Z4Q2-1", "protein_name": "HEAT repeat-containing protein 3", "gene_name": "HEATR3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGKSRTKRFKRPQFSPTGDCQAEAAAAANGTGGEEDDGPAAELLEKLQHPSAEVRECACAGLARLVQQRPALPGLARRDAVRRLGPLLLDPSLAVRETAAGALRNLSACGGFEVCDDMVTKDIMTPLVALLKECSAGLDSNEMSLQEKKDQNRNSIENIANETVNVLWNICECSSRAVSIFNKEGCLEIVLKYLSRFPTNVDLAISVAYCLQTVTEDNPELLKSFSATALNMLESALLSPVSSMESLLLKTLVAGTIWNLKDIIPCKSQAEIINALLKILSEVLGMDAGEMVIQMKEAETQRLKTAAEAEEILENTNGDDLIEDDEMEGISHKRRVRRKTFVSDLLPPTDKELRETIALLTAQQTALEIIVNMCCNEDPSDDEWEELSSSDESDAFMENSFSECGGQLFSPLCLSHEVHTALTNYLIPKKIFEKTAFPNSIAVDLCSRNPTWKPLIRKMNTIQCRALFCLQSLVSLLDVEHLGGAAALQTLAQHLSQLLFSQPDFAKHVDFLEAISSALRALLQTMASKNISQCMTPDQLMTLCKAGIHSSNVGVRVNVVSILGITGSVLAKEDGTLETLKNIGCFLLEVTTKDPSLVVAGEALDALFDVFADGKEAERASIQIKLLSALKEFQPVFKMKIRKEGRGNYSTDQLCVLDNVKMNLRRFIAYQETVEKRLTS", "length": 680 }, "evidence": [ { "id": "A0A8V1A4L3", "url": "https://omabrowser.org/oma/group/A0A8V1A4L3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q86HD4-1", "protein_name": "Armadillo repeat-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGKFTSSKKTYRVDPLGLNLPNNGFDNEELDTADNLSGIVAGGVVGATTDGNLIMNEDLSQSITDPIKLLDLISSSETVERDFAFRTISEFVLENESFTQELIKPENIRKIITRLVEPDVQIRVSVIGTFRNLTVVKEDICETLINLDILTPLLSNFVQGINFIKTLNEKDMKQQKSIETQHVLIQAVALINNLCEVSDKGFSIVSKECKSILTTLFEVLINNSIFMPELIMNISEFLTVVTDDNNELNATINNELMLQLFNIIKDSTTMNIRLKTLISTIILNIGQLYNKELVIQNITPILLSTFQFNSISTLNSDLLKSLNSAKDAKLKYDQLVAEQTDDNNNNNNDEKMGMDENSNNNNNDNNIEEPIDESKPITSTVDETIKKTPKNIIKNAAADLVQECEKQFKNQNEEWKDSLLAQQSAIELFVNIVSDAQQQQPDDSNPYDDDDDKFLDIEDGETEQSQQILSNISKFIISTPLCQYLIELLNSIVNFDSTEFGKLNIELLPNISSIRILQKRAMTCLSNLLITFIPKEENVQKILWDLLMKIANKSFTTNDIDIIEMTTSSLWSIMRTNSNIGFTTEIEIKNLVELAIKSPNSIKTNLIGIIGIAGQKPYCQNILKEVAMFLLQCLNKDLPADIISESLNSIFDIYAEPNVNNIVKEVSLIQHLDAFVPIIRNKIKTDKKKLDRALLDRLDESRINLSRFITYKKSQK", "length": 716 }, "evidence": [ { "id": "A0A8V1A4L3", "url": "https://omabrowser.org/oma/group/A0A8V1A4L3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8BQM4-1", "protein_name": "HEAT repeat-containing protein 3", "gene_name": "Heatr3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGKSRTKRFKRPQFSPIESCQAEAAAASNGTGDEEDDGPAAELLEKLQHPSAEVRECACAGLARLVQQRPALPDLARRDAVRRLGPLLLDSSLAVRETAAGALRNLSACGGFDVCDDMVAKDIMTPLVALLRECLSGLDSNEMSPQEKADKRNPVESIANEAVNVLWNVCECSGRAVSIFNKEGCLEIVLQYLRRFPTSIDLAVSVAYCLQTVTEDNPELLKSFDGTALRVLESALLCPVASMEYILLKTLVAGTIWNLKDIIPSKSQAEIINAILGALSEVLGMNTGNMVIQMKEAETQRLKTAAESEDILANANGDDLVEDDEMEEIPHKRKLRRKTFISDLLPPTDKELREAMALLTAQQTALEVIVNMCCSEDPSDDEWEELSSSDESEAFMENSFSECSGHLMSPLCLSHEIHSALTNCLIPEKVFEKTSSPNSVAVDICSKNPTWKPLIRKMNTIQCRALMCLQSLVSLLDIDHLGGAPALQTLAQHLSQILFSQPDFAKHDDFLEAISSALRALLQTMASKNIPQCMTPEQLMTLCREGIHSSSIGVRVNVVSILGITGSVLAKDDGTLDTLKTIGCFLLEVATKDPSLVVTGEALDALFDVFADGEAAEKASVQIKLLAALKEFQPVFKMKIRKEGRGKYSPDQLCVLDNVKMNLRRFIAYQETVEKRLTS", "length": 679 }, "evidence": [ { "id": "A0A8V1A4L3", "url": "https://omabrowser.org/oma/group/A0A8V1A4L3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VI15-1", "protein_name": "SYO1-like TPR repeats domain-containing protein", "gene_name": "Dmel\\CG10286", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MGKVRKVKTRTPSGVDTSAEIDVESAGEAEGCGPIEAICVHLQQANVEEKLNGLHSFAVLALRKEKVPEIRDSELVRIAAPLLCDKESAIRNAAAGAFRNLSVFGTEVCDFLVENDILTALLTLVRSYDLTKGGFENELHADTFQQAIHLLRNLCESSPTATEALNQANFLSSLLLGFDYRKFGLEVAISVAQLVLVVSENNSSSWNVLASSTILPELLVAPTESHAQLYLNALAAGILCNVPACAAAHTREILNSLDKLLSIDPQAQLQSCKSEILNAKSKNEAPVLEISMETEDMTETQSANQSKPNQCDAEVALKNLEHLLDAQRLVAEIITNLGSSDEQSNWDTDSEHSESESVADYDMEDETADSGSGGLPANFLETIKQNKVIEKLWQKAQPLQPAVENLVSQQENIKEKVEKLRVSYLICLQNLCNVLPPEDLGGCSNLYNMWMILGQQAFRGSEDVSVMEAITSLMRSSLSLLKSRKDLFGQMTENDLNMIIEGASKCTDINIRVNWNRMLGTLGSLLSEPLVKAIVLFLLTYCAQEDDLWALSEGLDALMDIFAVDDWPQIIAELEMCDRVQALEELFKSKLRQQRRELKERRATVQTVKTNFSRFVFYLNKNCKK", "length": 625 }, "evidence": [ { "id": "A0A8V1A4L3", "url": "https://omabrowser.org/oma/group/A0A8V1A4L3/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "erythrocyte maturation", "id": "GO:0043249", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043249", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A4L3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4L3" } ], "pmid": "" }, { "name": "ribosomal large subunit biogenesis", "id": "GO:0042273", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042273", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A4L3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4L3" } ], "pmid": "" }, { "name": "protein import into nucleus", "id": "GO:0006606", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006606", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A4L3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4L3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "unfolded protein binding", "id": "GO:0051082", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051082", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A4L3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4L3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 168, "end_pos": 170, "annotation": "n_glycosylation_sequon" }, { "start_pos": 526, "end_pos": 528, "annotation": "n_glycosylation_sequon" }, { "start_pos": 548, "end_pos": 550, "annotation": "n_glycosylation_sequon" }, { "start_pos": 99, "end_pos": 101, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1A4L3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4L3" }, { "id": "PF25567", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25567" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SYO1-like TPR repeats", "eco_id": "ECO_0000259", "start_pos": 412, "end_pos": 669, "start_aa": "Ala", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 168, "end_pos": 170 }, { "start_pos": 526, "end_pos": 528 }, { "start_pos": 548, "end_pos": 550 }, { "start_pos": 99, "end_pos": 101 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A4P1-1", "uniprot_ac": "A0A8V1A4P1", "uniprot_id": "A0A8V1A4P1_CHICK", "mass": { "chemical_mass": 63493.0, "monoisotopic_mass": 63493.0 }, "refseq": {}, "gene_names": [ { "name": "KRT75L2", "type": "recommended", "evidence": [ { "id": "A0A8V1A4P1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4P1" } ] } ], "protein_names": [ { "name": "IF rod domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8V1A4P1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4P1/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A4P1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4P1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "KRT75L2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4P1", "locus": {} } ], "crossref": [ { "id": "A0A8V1A4P1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A4P1", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR003054", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003054", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032444", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032444", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039008", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039008", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A4P1", "url": "https://www.orthodb.org/?gene=A0A8V1A4P1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45616", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45616", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45616:SF34", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45616:SF34", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00038", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00038", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16208", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16208", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-6805567", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6805567", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-6809371", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6809371", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1A4P1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4P1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A4P1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4P1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSRQSACRSYGGGSRRGYSSCSAIGGGFGGGGGSRSRISYSSYSSSRGGGGGGQCGGFSSRSLHNMGGSRGIAVGGCYGGGGRMGGYGGGIGGYGRGICGGGMGGYGGGIGGGGMGGFGGGMGGGGMGGGGMGGGGMGGFGGGIGGGIGGGMGGFGGPGFPGGIQPVHVDSSLLRPVHVEIDPQIQQVKNQEKEQIKTLNNQFASFIDKVRFLEQQNKVLSTKWELLQQQGPSGPRKNLDAIFENYIQGLRRRLESLLGQRGELESELQNMRQYVEEYKTKYEEEINRRTAAENEFVVLKKDVDCAYMTKVELEAKVGALTDEISFLRCIYEEELAQMQTISRDLSVVVSMDNNRHLDLDSIIEEVRRQYEQIAQNSRAEAEAWYQSRYEELQTTAGRHGDSLRNTKIEIQELTRNVQRLRAEIENVKKQNQQLQAAIAEAEERGEMALKDARRKLEELECALSKDKEELARLLKEYQELLNIKIALDVEIAMYRKLLEGEENRLCGDNPSNVNVSVVGRTTIAGGRAGGFGAGSGVGGGVCTVGGGSIIGGSCGVGGGVYNGGFSSGSGRMCSSGGGTFIPTGASSVRRCVTTTTVKSSGVKY", "length": 604, "header": "tr|A0A8V1A4P1-1|A0A8V1A4P1_CHICK Isoform 1 of IF rod domain-containing protein OS=Gallus gallus OX=9031 GN=KRT75L2 PE=3 SV=1 CANONICAL=A0A8V1A4P1-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A4P1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4P1/entry#A0A8V1A4P1-1", "sequence": { "sequence": "MSRQSACRSYGGGSRRGYSSCSAIGGGFGGGGGSRSRISYSSYSSSRGGGGGGQCGGFSSRSLHNMGGSRGIAVGGCYGGGGRMGGYGGGIGGYGRGICGGGMGGYGGGIGGGGMGGFGGGMGGGGMGGGGMGGGGMGGFGGGIGGGIGGGMGGFGGPGFPGGIQPVHVDSSLLRPVHVEIDPQIQQVKNQEKEQIKTLNNQFASFIDKVRFLEQQNKVLSTKWELLQQQGPSGPRKNLDAIFENYIQGLRRRLESLLGQRGELESELQNMRQYVEEYKTKYEEEINRRTAAENEFVVLKKDVDCAYMTKVELEAKVGALTDEISFLRCIYEEELAQMQTISRDLSVVVSMDNNRHLDLDSIIEEVRRQYEQIAQNSRAEAEAWYQSRYEELQTTAGRHGDSLRNTKIEIQELTRNVQRLRAEIENVKKQNQQLQAAIAEAEERGEMALKDARRKLEELECALSKDKEELARLLKEYQELLNIKIALDVEIAMYRKLLEGEENRLCGDNPSNVNVSVVGRTTIAGGRAGGFGAGSGVGGGVCTVGGGSIIGGSCGVGGGVYNGGFSSGSGRMCSSGGGTFIPTGASSVRRCVTTTTVKSSGVKY", "length": 604, "header": "tr|A0A8V1A4P1-1|A0A8V1A4P1_CHICK Isoform 1 of IF rod domain-containing protein OS=Gallus gallus OX=9031 GN=KRT75L2 PE=3 SV=1 CANONICAL=A0A8V1A4P1-1" }, "locus": { "chromosome": "34", "start_pos": 1955190, "end_pos": 1943514, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063204.1", "url": 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"MAGLGGLRAGGGGCVPATKVELTVSCRQLLDKDTFSKSDPLCVLYTQGPDTKQWREFGRTEVIDNSLNPDFVRKFVLNYFFEEKQNLRFDLYDVDSKSPDLSKHDFLGQAFCTLGEIVGSSGSRLEKPLTMGTVTAHPRSRKPAPAMSNGGIPGKKCGTIILLAEELGNCRDVATLQFCANKLDKKDFFGKSDPFMVFYRSNEDGTFTICHKTEVMRNTLNPVWPAFAIPVRALCNGDYDRAIKVEVYDWDRDGSHDFIGEFTTSYRELARGQSQFNVYEVVNPRKKMKKKKYLNSGTVTLLSFAVESDHTFLDYIRGGTQINFTVAIDFTASNGNPSQSTSLHYLSPYQLNAYTMALRAVGEIIQDYDSDKMFPALGFGAKIPPDGRVSHEFPLNGDAANPSCSGIEGILEAYHRSLRSVQLYGPTNFAPVVNHVARSAAAVPDGSQYFVLLIITDGVISDMAQTKEAIVNAAKLPMSIIIVGVGQAEFDAMVELDGDDIRISSRGKVAERDIVQFVPFRDYTDRGGSQVLSMARLAKDVLAEIPEQFISYMKAHGIKPQPAPPSPDPPGPPPPSQP", "length": 578, "header": "tr|A0A8V1A4Q2-1|A0A8V1A4Q2_CHICK Isoform 1 of Copine 5 OS=Gallus gallus OX=9031 GN=LOC101748755 PE=3 SV=1 CANONICAL=A0A8V1A4Q2-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A4Q2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Q2/entry#A0A8V1A4Q2-1", "sequence": { "sequence": "MAGLGGLRAGGGGCVPATKVELTVSCRQLLDKDTFSKSDPLCVLYTQGPDTKQWREFGRTEVIDNSLNPDFVRKFVLNYFFEEKQNLRFDLYDVDSKSPDLSKHDFLGQAFCTLGEIVGSSGSRLEKPLTMGTVTAHPRSRKPAPAMSNGGIPGKKCGTIILLAEELGNCRDVATLQFCANKLDKKDFFGKSDPFMVFYRSNEDGTFTICHKTEVMRNTLNPVWPAFAIPVRALCNGDYDRAIKVEVYDWDRDGSHDFIGEFTTSYRELARGQSQFNVYEVVNPRKKMKKKKYLNSGTVTLLSFAVESDHTFLDYIRGGTQINFTVAIDFTASNGNPSQSTSLHYLSPYQLNAYTMALRAVGEIIQDYDSDKMFPALGFGAKIPPDGRVSHEFPLNGDAANPSCSGIEGILEAYHRSLRSVQLYGPTNFAPVVNHVARSAAAVPDGSQYFVLLIITDGVISDMAQTKEAIVNAAKLPMSIIIVGVGQAEFDAMVELDGDDIRISSRGKVAERDIVQFVPFRDYTDRGGSQVLSMARLAKDVLAEIPEQFISYMKAHGIKPQPAPPSPDPPGPPPPSQP", "length": 578, "header": "tr|A0A8V1A4Q2-1|A0A8V1A4Q2_CHICK Isoform 1 of Copine 5 OS=Gallus gallus OX=9031 GN=LOC101748755 PE=3 SV=1 CANONICAL=A0A8V1A4Q2-1" }, "locus": { "chromosome": "26", "start_pos": 1235385, "end_pos": 1228472, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010060676.1", "url": "https://www.ensembl.org/id/ENSGALT00010060676.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010037435.1", "url": "https://www.ensembl.org/id/ENSGALP00010037435.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A286Y928-1", "protein_name": "Copine-8", "gene_name": "cpne5b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEGDIMDKLEDMASVYEFDPLTGNIPATKVEITVSCRNLLDRDTFSKSDPLCVLYTQGVETKQWREFGRTEVIDNTLNPDFVRKYILDYFFEEKQNLRFDLYDVDSKSPDLSKHKPLELYDFLGQMFCTLGEIVGSPASRLEKPLGGISGKNCGTIVLSAEELGNCRDSATMQFCANKLDKKDFFGKSDPFMVFYRSNEDGTFTICHKTEVVKNTLNPVWQPFTIPVRALCNGDYDRTIKVEVYDWDRDGSHDFIGEFTTSYRELARGQSQFNVYEVVNPKKKMKKKKYVNSGTVTLLSFSVESESTFLDYIKGGTQINFTVAIDFTASNGNPSQSTSLHYMNPYQMNAYALALKAVGEIIQDYDSDKMFPALGFGAKLPPDGRVSHEFPLNGNIENPYCNGIEGILEAYHQSLKTVQLYGPTNFAPVVNHVARYAAAVQDGSQYFILLIITDGVISDMSQTKEAIVNAAKLPMSIIIVGVGQAEFDAMVELDGDDIRISSRGKLAERDIVQFVPFRDYMDRTGNHVLSMARLAKDVLAEIPDQFISYMKSRGIKPNPAPPPYTPPGHTHHTQI", "length": 574 }, "evidence": [ { "id": "A0A8V1A4Q2", "url": "https://omabrowser.org/oma/group/A0A8V1A4Q2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A287A2T7-1", "protein_name": "Copine-5", "gene_name": "CPNE5", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEQPEDMASLSEFDSLAGSIPATKVEITVSCRNLLDKDMFSKSDPLCVMYTQGMENKQWREFGRTEVIDNTLNPDFVRKFIVDYFFEEKQNLRFDLYDVDSKSPDLSKHDFLGQAFCTLGEIVGSPGSRLEKSLTIGAFSLNSRTGKPMPAVSNGGVPGKKCGTIILSAEELSNCRDVATMQFCANKLDKKDFFGKSDPFLVFYRSNEDGTFTICHKTEVMKNTLNPVWQTFSIPVRALCNGDYDRTIKVEVYDWDRDGSHDFIGEFTTSYRELARGQSQFNIYEVVNPKKKMKKKKYVNSGTVTLLSFAVESECTFLDYIKGGTQINFTVAIDFTASNGNPSQSTSLHYMSPYQLNAYALALTAVGEIIQHYDSDKMFPALGFGAKLPPDGRVSHEFPLNGNQENPSCCGIDGILEAYHHSLRTVQLYGPTNFAPVVTHVARNAAAVQDGSQYSVLLIITDGVISDMAQTKEAIVNAAKLPMSIIIIGVGQAEFDAMVELDGDDVRISSRGKLAERDIVQFVPFRDYVDRTGNHVLSMARLARDVLAEIPDQLVSYMKAQGIRPRAPPTAPARSPPQSPTRTPPASPLHTHI", "length": 593 }, "evidence": [ { "id": "A0A8V1A4Q2", "url": "https://omabrowser.org/oma/group/A0A8V1A4Q2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A3Q1M6K0-1", "protein_name": "Copine-5", "gene_name": "CPNE5", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MEQPEDMASLSEFDSLAGSIPATKVEITVSCRNLLDKDMFSKSDPLCVMYTQGMENKQWREFGRTEVIDNTLNPDFVRKFIVDYFFEEKQNLRFDLYDVDSKSPDLSKHDFLGQAFCTLGEIVGSPGSRLEKSLTIGAFSLNSRTGKPMPAVSNGGVPGKKCGTIILSAEELSNCRDVATMQFCANKLDKKDFFGKSDPFLVFYRSNEDGTFTICHKTEVVKNTLNPVWQTFSIPVRALCNGDYDRTIKVEVYDWDRDGSHDFIGEFTTSYRELARGQSQFNIYEVVNPKKKMKKKKYVNSGTVTLLSFAVESECTFLDYIKGGTQINFTVAIDFTASNGNPSQSTSLHYMSPYQLNAYALALTAVGEIIQHYDSDKMFPALGFGAKLPPDGRVSHEFPLNGNQENPSCCGIDGILEAYHHSLRTVQLYGPTNFAPVVTHVARNAAAVQDGSQYSVLLIITDGVISDMAQTKEAIVNAAKLPMSIIIIGVGQAEFDAMVELDGDDVRISSRGKLAERDIVQFVPFRDYVDRTGNHVLSMARLARDVLAEIPDQLVSYMKAQGIRPRSPPMATARSPPQSPARTPPASPLHTHI", "length": 593 }, "evidence": [ { "id": "A0A8V1A4Q2", "url": "https://omabrowser.org/oma/group/A0A8V1A4Q2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "D3ZGN2-1", "protein_name": "Copine-5", "gene_name": "Cpne5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDQPEDMASLSEFDSLAGSIPATKVEITVSCRNLLDKDMFSKSDPLCVMYTQGMENKQWREFGRTEVIDNTLNPDFVRKFIVDYFFEEKQNLRFDLYDVDSKSPDLSKHDFLGQAFCTLGEIVGSSGSRLEKPLTIGTFSLNSRTGKPMPAVSNGGVPGKKCGTIILSAEELSNCRDVATMQFCANKLDKKDFFGKSDPFLVFYRSNEDGTFTICHKTEVMKNTLNPVWQTFSIPVRALCNGDYDRTIKVEVYDWDRDGSHDFIGEFTTSYRELARGQSQFNIYEVINPKKKMKKKKYVNSGTVTLLSFAVESESTFLDYIKGGTQINFTVAIDFTASNGNPSQSTSLHYMSPYQLNAYALALTAVGEIIQHYDSDKMFPALGFGAKLPPDGRVSHEFPLNGNQENPSCCGIDGILEAYHSSLRTVQLYGPTNFAPVVTHVARNAAAVQDGSQYSVLLIITDGVISDMAQTKEAIVNAAKLPMSIIIVGVGQAEFDAMVELDGDDVRISSRGKLAERDIVQFVPFRDYVDRTGNHVLSMARLARDVLAEIPDQLVSYMKAQGIRPRPPPAAPVQSPPQSPAHSPPGSPVHTHI", "length": 593 }, "evidence": [ { "id": "A0A8V1A4Q2", "url": "https://omabrowser.org/oma/group/A0A8V1A4Q2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q55GG1-1", "protein_name": "Copine-D", "gene_name": "cpnD", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNPIQPIPKSKIEIRIKCKDLTSKDLLSQSDPQAIVYLKQQQRNDWIQQGKTEKLKNQKSPEFKQSITVDYHFEEVQLLKIVVIDIDKDIKLLKDFDDHDLIGEVNVSLGSILSSPGGRMKMSLTKNGILSGSITISTEEIRETGANIYFALEGNHLDKKDLLSSDPYFKIYKSGGTLVYQSDVIKNTLNPTFPPVYLKLEELNGGDMFRELTFEFMDWDKIGDHDLIGRFTTNTDTILRGGALEFEIINPKKVGKSGYKNSGIIKFYIARIQGDPTFLDYLHGGLEINLMVAIDCTASNMPPDVSTSLHYNTPTQPSQYASSIAAVGNVLAPYDYDQMIEVVGFGGLYNGHTSHCFPFNLTNGDDNKSEAHGLQEVLDIYYNNVLKIPFSYPTNFENVIHHAIKRASKSTQSNQKYTVLLIITDGDISDTQKTIDELVSASKSALSVVIIGVGNYHFEAMKILDGDEKGLVDSKGNPSKRDICQFVPFNDFKNYPEALAHETLKEIPSQVLSFMKLSKIHPNQPRQFNC", "length": 530 }, "evidence": [ { "id": "A0A8V1A4Q2", "url": "https://omabrowser.org/oma/group/A0A8V1A4Q2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86YQ8-1", "protein_name": "Copine-8", "gene_name": "CPNE8", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDSRYNSTAGIGDLNQLSAAIPATRVEVSVSCRNLLDRDTFSKSDPICVLYVQGVGNKEWREFGRTEVIDNTLNPDFVRKFILDYFFEERENLRFDLYDVDSKSPNLSKHDFLGQVFCTLGEIVGSQGSRLEKPIVGIPGKKCGTIILTAEELNCCRDAVLMQFCANKLDKKDFFGKSDPFLVFYRSNEDGSFTICHKTEVVKNTLNPVWQAFKISVRALCNGDYDRTIKVEVYDWDRDGSHDFIGEFTTSYRELSRGQSQFNVYEVVNPKKKGKKKKYTNSGTVTLLSFLVETEVSFLDYIKGGTQINFTVAIDFTASNGNPAQPTSLHYMNPYQLNAYGMALKAVGEIVQDYDSDKMFPALGFGAKLPPDGRISHEFALNGNPQNPYCDGIEGVMEAYYRSLKSVQLYGPTNFAPVINHVARYASSVKDGSQYFVLLIVTDGVISDMAQTKESIVNASKLPMSIIIVGVGPAEFDAMVELDGDDVRVSSRGKYAERDIVQFVPFRDYIDRSGNHILSMARLAKDVLAEIPEQFLSYMRARGIKPSPAPPPYTPPTHVLQTQI", "length": 564 }, "evidence": [ { "id": "A0A8V1A4Q2", "url": "https://omabrowser.org/oma/group/A0A8V1A4Q2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8JZW4-1", "protein_name": "Copine-5", "gene_name": "Cpne5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEQPEDMASLSEFDSLAGSIPATKVEITVSCRNLLDKDMFSKSDPLCVMYTQGMENKQWREFGRTEVIDNTLNPDFVRKFIVDYFFEEKQNLRFDLYDVDSKSPDLSKHDFLGQAFCTLGEIVGSSGSRLEKPLTIGTFSLNSRTGKPMPAVSNGGVPGKKCGTIILSAEELSNCRDVATMQFCANKLDKKDFFGKSDPFLVFYRSNEDGTFTICHKTEVMKNTLNPVWQTFSIPVRALCNGDYDRTIKVEVYDWDRDGSHDFIGEFTTSYRELARGQSQFNIYEVINPKKKMKKKKYVNSGTVTLLSFAVESESTFLDYIKGGTQINFTVAIDFTASNGNPSQSTSLHYMSPYQLNAYALALTAVGEIIQHYDSDKMFPALGFGAKLPPDGRVSHEFPLNGNQENPSCCGIDGILEAYHSSLRTVQLYGPTNFAPVVTHVARNAAAVQDGSQYSVLLIITDGVISDMAQTKEAIVNAAKLPMSIIIVGVGQAEFDAMVELDGDDVRISSRGKLAERDIVQFVPFRDYVDRTGNHVLSMARLARDVLAEIPDQLVSYMKAQGIRPRPPPAAPAQSPPQSPAHSPPGSPVHTHI", "length": 593 }, "evidence": [ { "id": "A0A8V1A4Q2", "url": "https://omabrowser.org/oma/group/A0A8V1A4Q2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9HCH3-1", "protein_name": "Copine-5", "gene_name": "CPNE5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEQPEDMASLSEFDSLAGSIPATKVEITVSCRNLLDKDMFSKSDPLCVMYTQGMENKQWREFGRTEVIDNTLNPDFVRKFIVDYFFEEKQNLRFDLYDVDSKSPDLSKHDFLGQAFCTLGEIVGSPGSRLEKPLTIGAFSLNSRTGKPMPAVSNGGVPGKKCGTIILSAEELSNCRDVATMQFCANKLDKKDFFGKSDPFLVFYRSNEDGTFTICHKTEVMKNTLNPVWQTFSIPVRALCNGDYDRTIKVEVYDWDRDGSHDFIGEFTTSYRELARGQSQFNIYEVVNPKKKMKKKKYVNSGTVTLLSFAVESECTFLDYIKGGTQINFTVAIDFTASNGNPSQSTSLHYMSPYQLNAYALALTAVGEIIQHYDSDKMFPALGFGAKLPPDGRVSHEFPLNGNQENPSCCGIDGILEAYHRSLRTVQLYGPTNFAPVVTHVARNAAAVQDGSQYSVLLIITDGVISDMAQTKEAIVNAAKLPMSIIIVGVGQAEFDAMVELDGDDVRISSRGKLAERDIVQFVPFRDYVDRTGNHVLSMARLARDVLAEIPDQLVSYMKAQGIRPRPPPAAPTHSPSQSPARTPPASPLHTHI", "length": 593 }, "evidence": [ { "id": "A0A8V1A4Q2", "url": "https://omabrowser.org/oma/group/A0A8V1A4Q2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "positive regulation of dendrite extension", "id": "GO:1903861", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903861", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A4Q2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Q2" } ], "pmid": "" }, { "name": "cellular response to calcium ion", "id": "GO:0071277", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071277", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A4Q2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Q2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A4Q2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Q2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A4Q2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Q2" } ], "pmid": "" }, { "name": "calcium-dependent phospholipid binding", "id": "GO:0005544", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005544", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A4Q2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Q2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 323, "end_pos": 325, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1A4Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Q2" }, { "id": "PS50004", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50004" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 129, "start_aa": "Met", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1A4Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Q2" }, { "id": "PS50234", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50234" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "VWFA", "eco_id": "ECO_0000259", "start_pos": 323, "end_pos": 545, "start_aa": "Asn", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 323, "end_pos": 325 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { 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[ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A4S3-1", "uniprot_ac": "A0A8V1A4S3", "uniprot_id": "A0A8V1A4S3_CHICK", "mass": { "chemical_mass": 42412.0, "monoisotopic_mass": 42412.0 }, "refseq": { "ac": "XP_040562966", "name": "homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040562966" }, "gene_names": [ { "name": "HERPUD1", "type": "recommended", "evidence": [ { "id": "A0A8V1A4S3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4S3" } ] }, { "name": "HERPUD1", "type": "synonym", "evidence": [ { "id": "XP_040562966", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040562966" } ] } ], "protein_names": [ { "name": "Homocysteine inducible ER protein with ubiquitin like domain 1", "type": "synonym", "evidence": [ { "id": "A0A8V1A4S3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4S3/entry#names_and_taxonomy" } ] }, { "name": "homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein isoform X1", "type": "synonym", "evidence": [ { "id": "XP_040562966", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040562966" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052542.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040562966", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040562966" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A4S3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4S3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "HERPUD1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4S3", "locus": { "chromosome": "11", "start_pos": 602067, "end_pos": 596706, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010024370", "url": "https://www.ensembl.org/id/ENSGALG00010024370" } ] } } ], "crossref": [ { "id": "A0A8V1A4S3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A4S3", "database": "AlphaFoldDB", "categories": [] }, { "id": "415644", "url": "https://www.ncbi.nlm.nih.gov/gene/415644", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000626", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000626", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029071", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029071", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039751", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039751", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "MSTAWVF", "url": "https://omabrowser.org/oma/group/MSTAWVF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A4S3", "url": "https://www.orthodb.org/?gene=A0A8V1A4S3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12943", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12943", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12943:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12943:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "XP_040562966", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040562966", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1A4S3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4S3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A4S3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4S3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAEDLSLSLLVRSPARRHPDLRLRAAPAWSVRRLKAELRRRAPGAPAEEDQKLIYCGKLLLDHQLLREFLPGQEELHALHLVYNMRTPTDVPESSTEVKAAQPKHVTEASQEPAAASSGGGRLRCSPGGQAAAEADARPETPRHPFQAVPPGFSVYTTYSMLQMSWLQQIYARQYYMQYLASTAASADPSSTRRSSEIPVTPPAPLPDPFPAQNQPGDQNAAPQANVANQNLRMNAQGGPLMGEEEEGGNRDWLDWLYSATLFYVFVNIVYFYSSVSRFLLVMGGTVLMYLHHVGWFPFRQRRAQPFPDNVPPQAAVNQDQNNNLQQGGNAGRAEEPEALPDVGQVLPELPQVNPSLMSTAWLFFKTFFASLLPEGPRLTRN", "length": 382, "header": "tr|A0A8V1A4S3-1|A0A8V1A4S3_CHICK Isoform 1 of Homocysteine inducible ER protein with ubiquitin like domain 1 OS=Gallus gallus OX=9031 GN=HERPUD1 PE=1 SV=1 CANONICAL=A0A8V1A4S3-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A4S3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4S3/entry#A0A8V1A4S3-1", "sequence": { "sequence": "MAEDLSLSLLVRSPARRHPDLRLRAAPAWSVRRLKAELRRRAPGAPAEEDQKLIYCGKLLLDHQLLREFLPGQEELHALHLVYNMRTPTDVPESSTEVKAAQPKHVTEASQEPAAASSGGGRLRCSPGGQAAAEADARPETPRHPFQAVPPGFSVYTTYSMLQMSWLQQIYARQYYMQYLASTAASADPSSTRRSSEIPVTPPAPLPDPFPAQNQPGDQNAAPQANVANQNLRMNAQGGPLMGEEEEGGNRDWLDWLYSATLFYVFVNIVYFYSSVSRFLLVMGGTVLMYLHHVGWFPFRQRRAQPFPDNVPPQAAVNQDQNNNLQQGGNAGRAEEPEALPDVGQVLPELPQVNPSLMSTAWLFFKTFFASLLPEGPRLTRN", "length": 382, "header": "tr|A0A8V1A4S3-1|A0A8V1A4S3_CHICK Isoform 1 of Homocysteine inducible ER protein with ubiquitin like domain 1 OS=Gallus gallus OX=9031 GN=HERPUD1 PE=1 SV=1 CANONICAL=A0A8V1A4S3-1" }, "locus": { "chromosome": "11", "start_pos": 601274, "end_pos": 596754, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010059439.1", "url": "https://www.ensembl.org/id/ENSGALT00010059439.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036297.1", "url": "https://www.ensembl.org/id/ENSGALP00010036297.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 201, "start_aa": "Thr", "end_pos": 201, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr201", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A287BJ02-1", "protein_name": "Homocysteine inducible ER protein with ubiquitin like domain 1", "gene_name": "HERPUD1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEPEPEPVTLLVKSPNQRHRDLELSGDRSWSVGRLKAHLSRVYPERPRPEDQRLIYSGKLLLDHQCLRDLLPKQEKRHVLHLVCSVKSPSKIPEASTKVAESREQPAGLNQGPSPGDSSSDGLRQREVVRNPSPSGWENISRSDAAQLAFQGLGPGFSGYTTYGWLQLSWFQQMYARQYYMQYLAATAASGAFVPSPSAQEIPVVSAPAPAPIHNQFPAENQPANQNAAPQVVVNPGANQNLRMNAQGGPIVEEDDEINRDWLDWTYSAATFSVFLCILYFYSSLSRFLMVMGATIVMYLHHVGWFPFRQRPVQNLPNDGPPQEAVNQDPNNNFQEGPDPEIEDPNHLPPDRDVLDEEQTSPSFMSTAWLVFKTFFASLLPEGPPAIAN", "length": 389 }, "evidence": [ { "id": "A0A8V1A4S3", "url": "https://omabrowser.org/oma/group/A0A8V1A4S3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8C2N588-1", "protein_name": "Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein isoform X1", "gene_name": "Herpud1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEPEPQPEQVTLLVKSPNQRHRDLELSGDRSWSVSRLKAHLSRVYPERPRPEDQRLIYSGKLLLDHQCLRDLLPKQEKRHVLHLVCNVKNPSKMLEAKTKGAESTEQPANTDQAQHPQAQHPGDSSGDGLRQREVLRNLSPSGWENISRPEAVQQAFQGLGPGFSGYTTYGWLQLSWFQQIYARQYYMQYLAATAASGAFVPTPSAQEIPVVSTPTPAPIHNQFPAENQPANQNAAAQVVVNPGANQNLRMNAQGGPLVEEDDEINRDWLDWTYSAATFSVFLSILYFYSSLSRFLMVMGATVVMYLHHVGWFPFRQRPVQNFPDDGPPQEAANQDPNNNLQEGTDPETEDPNSLPPDHEVLDPEQTSPSFMSTAWLVFKTFFASLLPEGPPAIAN", "length": 396 }, "evidence": [ { "id": "A0A8V1A4S3", "url": "https://omabrowser.org/oma/group/A0A8V1A4S3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8I6B3C5-1", "protein_name": "Homocysteine inducible ER protein with ubiquitin like domain 1", "gene_name": "Herpud1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTQPRRVASARTLALSPPLRRLSPGADWATLGTDLCLSQWTAATESAICGILARGAHKRYPRRGRVSQRHQVSLWGRRRLRRRPFGIPERSRASSAADMEPEPQPEPVTLLVKSPNQRHRDLELSGDRGWSVSRLKAHLSRVYPERPRPEDQRLIYSGKLLLDHQCLQDLLPKQEKRHVLHLVCNVRSPSKKPEASTKGAESTEQPDNTSQAQYPGDSSSDGLREREVLRNLPPSGWENVSRPEAVQQTFQGLGPGFSGYTTYGWLQLSWFQQIYARQYYMQYLAATAASGAFGPTPSAQEIPVVSTPAPAPIHNQFPAENQPANQNAAAQAVVNPGANQNLRMNAQGGPLVEEDDEINRDWLDWTYSAATFSVFLSILYFYSSLSRFLMVMGATVVMYLHHVGWFPFRQRPVQNFPDDGPPQEAANQDPNNNLQGGLDPEMEDPNRLPVGREVLDPEHTSPSFMSTAWLVFKTFFASLLPEGPPALAN", "length": 489 }, "evidence": [ { "id": "A0A8V1A4S3", "url": "https://omabrowser.org/oma/group/A0A8V1A4S3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q15011-1", "protein_name": "Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein", "gene_name": "HERPUD1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MESETEPEPVTLLVKSPNQRHRDLELSGDRGWSVGHLKAHLSRVYPERPRPEDQRLIYSGKLLLDHQCLRDLLPKQEKRHVLHLVCNVKSPSKMPEINAKVAESTEEPAGSNRGQYPEDSSSDGLRQREVLRNLSSPGWENISRPEAAQQAFQGLGPGFSGYTPYGWLQLSWFQQIYARQYYMQYLAATAASGAFVPPPSAQEIPVVSAPAPAPIHNQFPAENQPANQNAAPQVVVNPGANQNLRMNAQGGPIVEEDDEINRDWLDWTYSAATFSVFLSILYFYSSLSRFLMVMGATVVMYLHHVGWFPFRPRPVQNFPNDGPPPDVVNQDPNNNLQEGTDPETEDPNHLPPDRDVLDGEQTSPSFMSTAWLVFKTFFASLLPEGPPAIAN", "length": 391 }, "evidence": [ { "id": "A0A8V1A4S3", "url": "https://omabrowser.org/oma/group/A0A8V1A4S3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9JJK5-1", "protein_name": "Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein", "gene_name": "Herpud1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEPEPQPEPVTLLVKSPNQRHRDLELSGDRSWSVSRLKAHLSRVYPERPRPEDQRLIYSGKLLLDHQCLQDLLPKQEKRHVLHLVCNVKNPSKMPETSTKGAESTEQPDNSNQTQHPGDSSSDGLRQREVLRNLSPSGWENISRPEAVQQTFQGLGPGFSGYTTYGWLQLSWFQQIYARQYYMQYLAATAASGTFVPTPSAQEIPVVSTPAPAPIHNQFPAENQPANQNAAAQAVVNPGANQNLRMNAQGGPLVEEDDEINRDWLDWTYSAATFSVFLSILYFYSSLSRFLMVMGATVVMYLHHVGWFPFRQRPVQNFPDDGGPRDAANQDPNNNLQGGMDPEMEDPNRLPPDREVLDPEHTSPSFMSTAWLVFKTFFASLLPEGPPALAN", "length": 391 }, "evidence": [ { "id": "A0A8V1A4S3", "url": "https://omabrowser.org/oma/group/A0A8V1A4S3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 9, "go_terms": [ { "name": "regulation of ERAD pathway", "id": "GO:1904292", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904292", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A4S3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4S3" } ], "pmid": "" }, { "name": "ubiquitin-dependent protein catabolic process", "id": "GO:0006511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006511", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A4S3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4S3" } ], "pmid": "" }, { "name": "endoplasmic reticulum unfolded protein response", "id": "GO:0030968", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030968", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A4S3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4S3" } ], "pmid": "" }, { "name": "endoplasmic reticulum calcium ion homeostasis", "id": "GO:0032469", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032469", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A4S3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4S3" } ], "pmid": "" }, { "name": "positive regulation of ERAD pathway", "id": "GO:1904294", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904294", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A4S3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4S3" } ], "pmid": "" }, { "name": "protein targeting to ER", "id": "GO:0045047", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045047", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A4S3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4S3" } ], "pmid": "" }, { "name": "negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway", "id": "GO:1902236", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902236", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A4S3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4S3" } ], "pmid": "" }, { "name": "retrograde protein transport, ER to cytosol", "id": "GO:0030970", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030970", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A4S3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4S3" } ], "pmid": "" }, { "name": "positive regulation of ubiquitin-dependent protein catabolic process", "id": "GO:2000060", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000060", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A4S3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4S3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A4S3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4S3" } ], "pmid": "" }, { "name": "endoplasmic reticulum quality control compartment", "id": "GO:0044322", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044322", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A4S3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4S3" } ], "pmid": "" }, { "name": "Lewy body core", "id": "GO:1990037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990037", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A4S3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4S3" } ], "pmid": "" }, { "name": "Hrd1p ubiquitin ligase complex", "id": 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yet known. Does not display detectable apoB mRNA editing. Has a low intrinsic cytidine deaminase activity. 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"https://www.ensembl.org/id/ENSGALG00010027623" } ] } } ], "crossref": [ { "id": "A0A8V1A4V2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A4V2", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd01283", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01283", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR002125", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002125", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016193", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016193", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050610", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050610", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR059135", "url": "https://www.ebi.ac.uk/interpro/entry/IPR059135", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A4V2", "url": 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"locus": { "chromosome": "26", "start_pos": 4757526, "end_pos": 4750659, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066927.1", "url": "https://www.ensembl.org/id/ENSGALT00010066927.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040939.1", "url": "https://www.ensembl.org/id/ENSGALP00010040939.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "positive regulation of gene expression via chromosomal CpG island demethylation", "id": "GO:0044029", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044029", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A4V2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V2" } ], "pmid": "" }, { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A4V2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V2" } ], "pmid": "" }, { "name": "cytidine to uridine editing", "id": "GO:0016554", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016554", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A4V2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A4V2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V2" } ], "pmid": "" }, { "name": "cytidine deaminase activity", "id": "GO:0004126", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004126", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A4V2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V2" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A4V2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A4V2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V2" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A4V2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V2" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A4V2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 124, "end_pos": 126, "annotation": "n_glycosylation_sequon" }, { "start_pos": 74, "end_pos": 76, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "21772", "name": "", "equation": "cytidine(6666) in apoB mRNA + H2O + H(+) = uridine(6666) in apoB mRNA + NH4(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V1A4V2-1" ], "evidence": [ { "id": "21772", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/21772" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A8V1A4V2", "gene_name": "APOBEC2", "activity": [ { "ec_number": "3.5.4.36", "activity": "cytidine(6666) in apoB mRNA + H2O + H(+) = uridine(6666) in apoB mRNA + NH4(+).", "evidence": [ { "id": "A0A8V1A4V2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V2" } ] }, { "ec_number": "3.5.4.36", "activity": "", "evidence": [ { "id": "A0A8V1A4V2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V2" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1A4V2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V2" }, { "id": "PS51747", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51747" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CMP/dCMP-type deaminase", "eco_id": "ECO_0000259", "start_pos": 50, "end_pos": 175, "start_aa": "Val", "end_aa": "Met", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.5.4.36", "ec_name": "cytidine(6666) in apoB mRNA + H2O + H(+) = uridine(6666) in apoB mRNA + NH4(+).", "evidence": [ { "id": "3.5.4.36", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.4.36" }, { "id": "3.5.4.36", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.5.4.36" } ] } ], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 124, "end_pos": 126 }, { "start_pos": 74, "end_pos": 76 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { 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{ "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A4Y7-1", "uniprot_ac": "A0A8V1A4Y7", "uniprot_id": "A0A8V1A4Y7_CHICK", "mass": { "chemical_mass": 24848.0, "monoisotopic_mass": 24848.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Integrase catalytic domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8V1A4Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Y7/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus 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"ac": "XP_004948094", "name": "E3 ubiquitin-protein ligase RNF26", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004948094" }, "gene_names": [ { "name": "RNF26", "type": "recommended", "evidence": [ { "id": "A0A8V1A4Z4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Z4" } ] }, { "name": "RNF26", "type": "synonym", "evidence": [ { "id": "XP_004948094", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004948094" } ] } ], "protein_names": [ { "name": "E3 ubiquitin-protein ligase RNF26", "type": "recommended", "evidence": [ { "id": "A0A8V1A4Z4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Z4/entry#names_and_taxonomy" } ] }, { "name": "2.3.2.27", "type": "synonym", "evidence": [ { "id": "A0A8V1A4Z4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Z4/entry#names_and_taxonomy" } ] }, { "name": "E3 ubiquitin-protein ligase RNF26", "type": "synonym", "evidence": [ { "id": "XP_004948094", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004948094" } ] }, { "name": "RING finger protein 26", "type": "synonym", "evidence": [ { "id": "A0A8V1A4Z4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Z4/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052555.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004948094.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004948094", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004948094" } ] }, { "annotation": "E3 ubiquitin-protein ligase that plays a key role in endosome organization by retaining vesicles in the perinuclear cloud. Acts as a platform for perinuclear positioning of the endosomal system by mediating ubiquitination of SQSTM1 through interaction with the ubiquitin conjugating enzyme UBE2J1. Ubiquitinated SQSTM1 attracts specific vesicle-associated adapters, forming a molecular bridge that restrains cognate vesicles in the perinuclear region and organizes the endosomal pathway for efficient cargo transport. Also acts as a regulator of type I interferon production in response to viral infection by mediating the formation of 'Lys-11'-linked polyubiquitin chains on TMEM173/STING, leading to stabilize TMEM173/STING. Also required to limit type I interferon response by promoting autophagic degradation of IRF3.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A4Z4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Z4#function" }, { "database": "UniProtKB", "id": "ARBA00057605", "url": "https://www.uniprot.org/uniprotkb/ARBA00057605#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A4Z4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Z4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RNF26", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Z4", "locus": { "chromosome": "24", "start_pos": 4031110, "end_pos": 4265650, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010025983", "url": "https://www.ensembl.org/id/ENSGALG00010025983" } ] } } ], "crossref": [ { "id": "A0A8V1A4Z4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A4Z4", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd16788", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16788", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "769803", "url": "https://www.ncbi.nlm.nih.gov/gene/769803", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040089", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040089", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:769803", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:769803", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TAILLWT", "url": "https://omabrowser.org/oma/group/TAILLWT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A4Z4", "url": "https://www.orthodb.org/?gene=A0A8V1A4Z4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22696", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22696", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22696:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22696:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13920", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13920", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004948094", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004948094", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1A4Z4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Z4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A4Z4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Z4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MELVLLLLRGLRLALDLLLLLLDLNFFLVSSLVTALLWLLTTAASLPGAATAGMWACWNGLLGGLCGLAEAACGLALGAMQGLGGLLRGCCSALEGLKVLGHLLTHLGLRGRELLQRGLCSLLGSGQALLREAGEGLAIGVSLLAYLVNSMVNLCLLGTQNFFTLLLALWDSVVSPVLRVADLLAAFMAHVSSSAIAISILLWSPCQLAFELLVSTTELLIGIFFVNVYGLALLLAIIVVSTVIFNPGLLLTLLGHVLGYFHTLPAYPRLQQEVWRLYQMAVLMMGMALTSQTWRRLVDWSLQVTNWSRGGRTMNRESDRRGTAQGLGRLMLAGDSHAAAQQEEQPDAEQVPQAHPSLSRSTVSGQRLQAPRDEPSTSWGKAPRREQLNAAAGDGAGVPDDDPWMLLKEQEERKKCVICQDQTKTVLLLPCRHLCLCQECTEVLLQQAIYQRNCPLCRQMILQTLNVYL", "length": 469, "header": "tr|A0A8V1A4Z4-1|A0A8V1A4Z4_CHICK Isoform 1 of E3 ubiquitin-protein ligase RNF26 OS=Gallus gallus OX=9031 GN=RNF26 PE=4 SV=1 CANONICAL=A0A8V1A4Z4-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A4Z4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Z4/entry#A0A8V1A4Z4-1", "sequence": { "sequence": "MELVLLLLRGLRLALDLLLLLLDLNFFLVSSLVTALLWLLTTAASLPGAATAGMWACWNGLLGGLCGLAEAACGLALGAMQGLGGLLRGCCSALEGLKVLGHLLTHLGLRGRELLQRGLCSLLGSGQALLREAGEGLAIGVSLLAYLVNSMVNLCLLGTQNFFTLLLALWDSVVSPVLRVADLLAAFMAHVSSSAIAISILLWSPCQLAFELLVSTTELLIGIFFVNVYGLALLLAIIVVSTVIFNPGLLLTLLGHVLGYFHTLPAYPRLQQEVWRLYQMAVLMMGMALTSQTWRRLVDWSLQVTNWSRGGRTMNRESDRRGTAQGLGRLMLAGDSHAAAQQEEQPDAEQVPQAHPSLSRSTVSGQRLQAPRDEPSTSWGKAPRREQLNAAAGDGAGVPDDDPWMLLKEQEERKKCVICQDQTKTVLLLPCRHLCLCQECTEVLLQQAIYQRNCPLCRQMILQTLNVYL", "length": 469, "header": "tr|A0A8V1A4Z4-1|A0A8V1A4Z4_CHICK Isoform 1 of E3 ubiquitin-protein ligase RNF26 OS=Gallus gallus OX=9031 GN=RNF26 PE=4 SV=1 CANONICAL=A0A8V1A4Z4-1" }, "locus": { "chromosome": "24", "start_pos": 4031110, "end_pos": 4026644, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063373.1", "url": "https://www.ensembl.org/id/ENSGALT00010063373.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039113.1", "url": "https://www.ensembl.org/id/ENSGALP00010039113.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:769803", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:769803", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0AAA9TX98-1", "protein_name": "E3 ubiquitin-protein ligase RNF26", "gene_name": "RNF26", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MEAVYLVVNGVGLLLDVLTLVLDLNFLLVSSLLASLAWLLAFIYNLPHTVLTSLLHLGRGVLLSLLALIEAMVRFTCGGLQALSTVLYSCSSGLESLKLLGHLASHGALRSREILHRGVLNMVSNGHALLRQICDVCAITMSLVAYVINSLVNICLIGTQNFFSLVLALWDAVMGPLWRMTDVVAAFLAHISSSAVAMSILLWTPCQLVLELLASAARLLGSFVLVNLTGLVLLACVLAVTVTLLHPDLTLRLATRALSQLHARPSYHRLREDVVRLSRLVLGLEAWRRVWSRSLQLASWPNRGGAPGAPQGGPRRLTSARTWRQDALPEAGPRSEAEEEEVRMARVTAARGRERLNEEESVAGQDPWKLLKEQEERKKCVICQDQSKTVLLLPCRHLCLCQACTEILMRHPVYHRNCPLCRQGILQTLNVYL", "length": 433 }, "evidence": [ { "id": "A0A8V1A4Z4", "url": "https://omabrowser.org/oma/group/A0A8V1A4Z4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1QZ63-1", "protein_name": "E3 ubiquitin-protein ligase RNF26", "gene_name": "rnf26", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLIMGVLNIVFSTVGKCVDVICLLLDLNFVIVSSLIQLLVSVLSFINSLPMLLTNSVFECWNLTLLCIITMRDGVTVVTHNMVGGWTQLLGGVLESFKIIGYLSSHLLLRTKELLHRGLLSGHGLLRQAWEGFGILFSLLLYFINTIVNLLLIGTQNLYSLLVSTVEAVSCPLQKALELALTVLTFLYSSLVGTSILLWTPCRLAMEFLGSACHIFVSIFLLNSYGLLLTLVIITGATVYLNPALPRQVSLRMITYVNTVPILRRLQMVLQRLYVLERNVWQRLAWHRSRIGLLVAAERDIGQAEPNIEPQVELNVPNQEVEDVPEDAPQPDIPLPSSSAHRPLRKFPSEDSCRGPPTDNLLNLLQEQEERKKCVICQDSTKTVVLLPCRHLCLCRECTNILLRQPMYQQNCPLCRHMILQTMDVYL", "length": 427 }, "evidence": [ { "id": "A0A8V1A4Z4", "url": "https://omabrowser.org/oma/group/A0A8V1A4Z4/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1SAF9-1", "protein_name": "E3 ubiquitin-protein ligase RNF26", "gene_name": "RNF26", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEAVYLVVNGVGLLLDVLTLVLDLNFLLVSSLLASLAWLLAFIYNLPHTVLTSLLHLGRGVLLSLLALIETVVRFTFGGLQALCTVLYSCYSGLESLKLLGHLASHGALRSREILHRGVLNMVSSGHALLRQACDICAITMSLVAYVINSLVNICLIGTQNLFSLVLALWDAVMGPLWRMTDVVAAFLAHISSSAVAMSILLWTPCQLVLELLASAARFLASFVLVNLTGLALLACVLAVTVTVLHPDLTLRLASRAFSQLHARPSYHRLREDVVRLSRLALGLEAWRRVWSRSLQLASWPNRGGAPGAPQGGPRRVPSDRTWRQDTLPEAGPRTEAEGEEVRMARMTAARGRERLNVEEPIAGQDPWKLLKEQEERKKCVICQDQSKTVLLLPCRHLCLCQACTEILMRHPVYHRNCPLCRRGILQTLNVYL", "length": 433 }, "evidence": [ { "id": "A0A8V1A4Z4", "url": "https://omabrowser.org/oma/group/A0A8V1A4Z4/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q8BUH7-1", "protein_name": "E3 ubiquitin-protein ligase RNF26", "gene_name": "Rnf26", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEAVYLVVNGVGLVLDLLTLMLDLNFLLVSSLLATLAWLLAFIYNLPHTVLTSLLHLGRGFLLSLLALVEAVVRFTFGGLQALGTLLYSCYSGLESLKLLGHLASHGALRSREFLNRGILNMVSNGHALLRQACDICAIAMSLVAYVINSLVNICLISTQNFFSLVLALWDAVTGPLWRMTDVVAAFLAHISSSAVAMAILLWTPCQLALELLASAARLLASCVVFHLTGLVLLACVLAVILIVLHPEQTLRLATQALSQLHARPSYHRLWEDIVRLTRLPLGLEAWRRVWSRSLQLASWPNRGGAPGAPQGGPRRVFSARIQPQDTPPEAEEEVIRTAPARGREQLNEDEPAAGQDPWKLLKEQEERKKCVICQDQSKTVLLLPCRHLCLCQACTEILMRHPVYHRNCPLCRRSILQTLNVYL", "length": 424 }, "evidence": [ { "id": "A0A8V1A4Z4", "url": "https://omabrowser.org/oma/group/A0A8V1A4Z4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9BY78-1", "protein_name": "E3 ubiquitin-protein ligase RNF26", "gene_name": "RNF26", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEAVYLVVNGLGLVLDVLTLVLDLNFLLVSSLLASLAWLLAFVYNLPHTVLTSLLHLGRGVLLSLLALIEAVVRFTCGGLQALCTLLYSCCSGLESLKLLGHLASHGALRSREILHRGVLNVVSSGHALLRQACDICAIAMSLVAYVINSLVNICLIGTQNLFSLVLALWDAVTGPLWRMTDVVAAFLAHISSSAVAMAILLWTPCQLALELLASAARLLASFVLVNLTGLVLLACVLAVTVTVLHPDFTLRLATQALSQLHARPSYHRLREDVMRLSRLALGSEAWRRVWSRSLQLASWPNRGGAPGAPQGDPMRVFSVRTRRQDTLPEAGRRSEAEEEEARTIRVTPVRGRERLNEEEPPGGQDPWKLLKEQEERKKCVICQDQSKTVLLLPCRHLCLCQACTEILMRHPVYHRNCPLCRRGILQTLNVYL", "length": 433 }, "evidence": [ { "id": "A0A8V1A4Z4", "url": "https://omabrowser.org/oma/group/A0A8V1A4Z4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A4Z4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Z4" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A4Z4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Z4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A4Z4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Z4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "endosome organization", "id": "GO:0007032", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007032", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A4Z4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Z4" } ], "pmid": "" }, { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A4Z4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Z4" } ], "pmid": "" }, { "name": "protein K11-linked ubiquitination", "id": "GO:0070979", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070979", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A4Z4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Z4" } ], "pmid": "" }, { "name": "ubiquitin-dependent protein catabolic process", "id": "GO:0006511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006511", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A4Z4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Z4" } ], "pmid": "" }, { "name": "protein localization to perinuclear region of cytoplasm", "id": "GO:1905719", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905719", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A4Z4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Z4" } ], "pmid": "" }, { "name": "negative regulation of defense response to virus", "id": "GO:0050687", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050687", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A4Z4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Z4" } ], "pmid": "" }, { "name": "regulation of type I interferon production", "id": "GO:0032479", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032479", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A4Z4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Z4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 306, "end_pos": 308, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1A4Z4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Z4" }, { "id": "PS50089", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50089" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RING-type", "eco_id": "ECO_0000259", "start_pos": 416, "end_pos": 458, "start_aa": "Cys", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.3.2.27", "ec_name": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "2.3.2.27", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.3.2.27" } ] } ], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 306, "end_pos": 308 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { 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"count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A4Z6-1", "uniprot_ac": "A0A8V1A4Z6", "uniprot_id": "A0A8V1A4Z6_CHICK", "mass": { "chemical_mass": 19985.0, "monoisotopic_mass": 19985.0 }, "refseq": {}, "gene_names": [ { "name": "C9ORF58", "type": "recommended", "evidence": [ { "id": "A0A8V1A4Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Z6" } ] } ], "protein_names": [ { "name": "Allograft inflammatory factor 1 like", "type": "synonym", "evidence": [ { "id": "A0A8V1A4Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Z6/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A4Z6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Z6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "C9ORF58", 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"length": 163, "header": "tr|A0A8V1AH83-1|A0A8V1A4Z6_CHICK Computationally mapped isoform of Allograft inflammatory factor 1 like OS=Gallus gallus OX=9031 GN=C9ORF58 PE=1 SV=1 CANONICAL=A0A8V1A4Z6-1" }, "locus": { "chromosome": "17", "start_pos": 6694210, "end_pos": 6685211, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067027.1", "url": "https://www.ensembl.org/id/ENSGALT00010067027.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040985.1", "url": "https://www.ensembl.org/id/ENSGALP00010040985.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "actin filament", "id": "GO:0005884", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005884", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A4Z6", "url": 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"protein_names": [ { "name": "TBC/LysM-associated domain containing 2", "type": "synonym", "evidence": [ { "id": "A0A8V1A503", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A503/entry#names_and_taxonomy" } ] }, { "name": "TLD domain-containing protein 2 isoform X5", "type": "synonym", "evidence": [ { "id": "XP_015151764", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015151764" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052551.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015151764.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015151764", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015151764" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A503", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A503" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TLDC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A503", "locus": { "chromosome": "20", "start_pos": 938521, "end_pos": 934698, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010024418", "url": "https://www.ensembl.org/id/ENSGALG00010024418" } ] } } ], "crossref": [ { "id": "A0A8V1A503", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A503", "database": "AlphaFoldDB", "categories": [] }, { "id": "101747236", 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"Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015151764", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015151764", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1A503", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A503", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A503-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A503-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRGLRAHYHLLPDQDEDLPTDCTEPDSEGQPGWEGAPVTSTAPEEPCRLVLSTPSSILQEREIEELGLHLPTRLRQQPWSLLYCTARDGFSLRTLYRCTSQLSSPALLLIRDTEAQAFGAFSTSPIHVSSGFYGTGETFLFSFSPELKVFRWTGRNNFFLKGDVDMLMVGAGSGKFGLWLDGDLHHGGSCPCETFNNESLSPRGEFCVRDLEVWGLA", "length": 217, "header": "tr|A0A8V1A503-1|A0A8V1A503_CHICK Isoform 1 of TBC/LysM-associated domain containing 2 OS=Gallus gallus OX=9031 GN=TLDC2 PE=4 SV=1 CANONICAL=A0A8V1A503-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A503-1", "url": 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"type": "synonym", "evidence": [ { "id": "NP_989524", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989524" } ] }, { "name": "bar class homeoprotein Barx1b", "type": "synonym", "evidence": [ { "id": "NP_989524", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989524" } ] }, { "name": "homeobox protein BarH-like 1b", "type": "synonym", "evidence": [ { "id": "NP_989524", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989524" } ] }, { "name": "homeobox protein BarH-like 1", "type": "synonym", "evidence": [ { "id": "NP_989524", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989524" } ] }, { "name": "homeodomain-containing transcription factor BarX-1", "type": "synonym", "evidence": [ { "id": "NP_989524", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989524" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AB044371.1, AF116460.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992432, SAMEA103992440 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000252.1. On Sep 23, 2021 this sequence version replaced NP_989524.1.", "evidence": [ { "database": "RefSeq", "id": "NP_989524", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989524" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A521", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A521" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "BARX1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A521", "locus": { "chromosome": "12", "start_pos": 6320900, "end_pos": 6318418, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027671", "url": "https://www.ensembl.org/id/ENSGALG00010027671" } ] } } ], "crossref": [ { "id": "A0A8V1A521", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A521", "database": "AlphaFoldDB", "categories": [] 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"https://www.ebi.ac.uk/interpro/entry/pfam/PF00046", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_989524", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989524", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1A521", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A521", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A521-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A521-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQHPLELGAAHYFPAEAFPDHRSHRYRSFMIEEILTDPPDAKGAAPPGELLKFGVQALLSARPYHSHLAVLKAEPAAVFKFPLAPLGCSGLGSALLAAGSGLQGGSASPHLPLELHLRGKLEPGGPETGSKAKKGRRSRTVFTELQLMGLEKRFEKQKYLSTPDRIDLAESLGLSQLQVKTWYQNRRMKWKKIVLQGGGLESPTKPKGRPKKNSIPSSEQLSEQERARDAEKPPESLGSPAEVSQEE", "length": 247, "header": "tr|A0A8V1A521-1|A0A8V1A521_CHICK Isoform 1 of BARX homeobox 1 OS=Gallus gallus OX=9031 GN=BARX1 PE=3 SV=1 CANONICAL=A0A8V1A521-1" }, "isoforms": [ { "isoform_ac": 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"glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q9ER42-1", "protein_name": "Homeobox protein BarH-like 1", "gene_name": "Barx1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQRPGEPGAARFGPPEGCADHRPHRYRSFMIEEILTEPPGPKGAAPAAAAAAAGELLKFGVQALLAARPFHSHLAVLKAEQAAVFKFPLAPLGCSGLGSALLAAGPGMPGPAGASHLPLELQLRGKLEAAGSGEPGAKAKKGRRSRTVFTELQLMGLEKRFEKQKYLSTPDRIDLAESLGLSQLQVKTWYQNRRMKWKKIVLQGGGLESPTKPKGRPKKNSIPTSEQLTEQERAKETEKPAETPGEPSDRNCED", "length": 254 }, "evidence": [ { "id": "A0A8V1A521", "url": "https://omabrowser.org/oma/group/A0A8V1A521/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9HBU1-1", "protein_name": "Homeobox protein BarH-like 1", "gene_name": "BARX1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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"strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010026001", "url": "https://www.ensembl.org/id/ENSGALG00010026001" } ] } } ], "crossref": [ { "id": "A0A8V1A543", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A543", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd01274", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01274", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd09499", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09499", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd09500", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09500", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "419898", "url": "https://www.ncbi.nlm.nih.gov/gene/419898", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001660", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001660", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006020", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006020", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013761", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013761", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033635", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033635", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041880", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041880", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041882", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041882", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A535", "url": "https://www.orthodb.org/?gene=A0A8V1A535", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A543", "url": "https://www.orthodb.org/?gene=A0A8V1A543", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A7F0", "url": "https://www.orthodb.org/?gene=A0A8V1A7F0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A7G3", "url": "https://www.orthodb.org/?gene=A0A8V1A7G3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ACF3", "url": "https://www.orthodb.org/?gene=A0A8V1ACF3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ACG3", "url": "https://www.orthodb.org/?gene=A0A8V1ACG3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24174", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24174", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24174:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24174:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00536", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00536", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00640", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00640", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12796", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12796", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13857", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13857", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1A535", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A535", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A535-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A535-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A543", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A543", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A543-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A543-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A7F0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7F0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A7F0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7F0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A7G3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7G3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A7G3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7G3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ACF3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ACF3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ACG3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACG3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ACG3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACG3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGKEQELLEAARTGNLPAVEKLLSGKRLSSGFGSGGSGGGGGGGSGGGGGGGSGGGGGGGGGGVGHPLSSLLSIWRGPNVNCVDSTGYTPLHHAALNGHKDVVEVLLRNDALTNVADCKGCYPLHLAAWKGDADIVKLLIHQGPSHTKVNEQNNDNETALHCAAQYGHTEVVKVLLEELTDPTMRNNKFETPLDLAALYGRLEVVKMLLNAHPNLLSCNTKKHTPLHLAARNGHKTVVHVLLDAGMDSNYQTEKGSALHEAALFGKTDVVQILLAAGIDVNIKDNRGLTALDIVRELPSQKSQHIAALIEDYTTGKKSAKAAEKTAQAPPAPTTDPACWIPQGDVEKAVTELIIDFDVNPEEESPYEALYNATSCHSLDSLASGRSSDRESVNKEVEAAGLKAAGVRPRERPPPPAKPPPDEEEEQHTEKMGHGASCEATVARGKSRGSGAEEEEHPYELLLTAETKKPVAVDRKTKDHRRSSGGRSQDPADPQDIQVPEQFSGLLHGSSPICEISEDPFRLVPSAEKGGVEAASHPPAMQLEDADLPASASAPTGSPDQNQKAIYATVQHTHSNRADPETVGTPHVLQHPGGAEDEGDRGGAAGRAHPGSKPKAELKLSRSLSKSDSDLLTCSPTEDDAMGSRSESLSNCSTGKKRLEKSPSFASEWDEIEKIMSSIGEGIDFSQEQQRISGSRMLEQSVGEWLESIGLQQYESKLLLNGFDDVRFLGCNVMEDQDLRDIGIGDPQHRRKLLQAARSLPKLKPLGCDGNSQPSVPAWLDSLGLQDYIQSFLSSGYSSIDTVKNLWELEIVNVLKVNLLGHRKRIIASLADRPYEEPPAKPPRFSQLRCQDLMSQTSSPLSQNDSCTGRSADLLLPSGDSGKRQHERGSELATYSKVERYKAQEDRRESKLTLRPPSLAAPYAPVQNWQHQPEKLIFESCGYEANYLGSMLIKDLRGTESTQDACAKMRKSTEHMKKIPTIILSITYKGVKFIDASNKNVIAEHEIRNISCAAQDPEDLCTFAYITKDLQTSHHYCHVFSTVDVNLTYEIILTLGQAFEVAYQLALQAQRAKPPGAAAGETIETKSSKPVPKPRAGMRKSAVPLPPDTRCCYCHTCTTHRPSYLPLQSVSPGAKLEPPEMDQDSQSHASVSWVVDPKQDSKRTLSTN", "length": 1167, "header": "tr|A0A8V1A543-1|A0A8V1A543_CHICK Isoform 1 of Ankyrin repeat and sterile alpha motif domain containing 1A OS=Gallus gallus OX=9031 GN=ANKS1A PE=1 SV=1 CANONICAL=A0A8V1A543-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A535-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A543/entry#A0A8V1A535-1", "sequence": { "sequence": "MKSLPRGANVLLRNAKNICIWRGPNVNCVDSTGYTPLHHAALNGHKDVVEVLLRNDALTNVADCKGCYPLHLAAWKGDADIVKLLIHQGPSHTKVNEQNALEIKELKKYGPFDPYINAKNNDNETALHCAAQYGHTEVVKVLLEELTDPTMRNNKFETPLDLAALYGRLEVVKMLLNAHPNLLSCNTKKHTPLHLAARNGHKTVVHVLLDAGMDSNYQTEKGSALHEAALFGKTDVVQILLAAGIDVNIKDNRGLTALDIVRELPSQKSQHIAALIEDYTTGKKSAKAAEKTAQAPPAPTTDPACWIPQGDVEKAVTELIIDFDVNPEEESPYEALYNATSCHSLDSLASGRSSDRESVNKEVEAAGLKAAGVRPRERPPPPAKPPPDEEEEQHTEKMGHGASCEATVARGKSRGSGAEEEEHPYELLLTAETKKPVAVDRKTKDHRRSSGGRSQDPADPQDIQVPEQFSGLLHGSSPICEISEDPFRLVPSAEKGGVEAASHPPAMQLEDADLPASASAPTGSPDQNQKAIYATVQHTHSNRADPETVGTPHVLQHPGGAEDEGDRGGAAGRAHPGSKPKAELKLSRSLSKSDSDLLTCSPTEDDAMGSRSESLSNCSTGKKRLEKSPSFASEWDEIEKIMSSIGEGIDFSQEQQRISGSRMLEQSVGEWLESIGLQQYESKLLLNGFDDVRFLGCNVMEDQDLRDIGIGDPQHRRKLLQAARSLPKLKPLGCDGNSQPSVPAWLDSLGLQDYIQSFLSSGYSSIDTVKNLWELEIVNVLKVNLLGHRKRIIASLADRPYEEPPAKPPRFSQLRCQDLMSQTSSPLSQNDSCTGRSADLLLPSGDSGKRQHERGSELATYSKVERYKAQEDRRESKLTLRPPSLAAPYAPVQNWQHQPEKLIFESCGYEANYLGSMLIKDLRGTESTQDACAKMRKSTEHMKKIPTIILSITYKGVKFIDASNKNVIAEHEIRNISCAAQDPEDLCTFAYITKDLQTSHHYCHVFSTVDVNLTYEIILTLGQAFEVAYQLALQAQRAKPPGAAAGETIETKSSKPVPKPRAGMRKSALEPPEMDQDSQSHASVSWVVDPKQDSKRTLSTN", "length": 1101, "header": "tr|A0A8V1A535-1|A0A8V1A543_CHICK Computationally mapped isoform of Ankyrin repeat and sterile alpha motif domain containing 1A OS=Gallus gallus OX=9031 GN=ANKS1A PE=1 SV=1 CANONICAL=A0A8V1A543-1" }, "locus": { "chromosome": "26", "start_pos": 4309046, "end_pos": 4229879, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063425.1", "url": "https://www.ensembl.org/id/ENSGALT00010063425.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039151.1", "url": "https://www.ensembl.org/id/ENSGALP00010039151.1" } ] } }, { "isoform_ac": "A0A8V1A543-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A543/entry#A0A8V1A543-1", "sequence": { "sequence": "MGKEQELLEAARTGNLPAVEKLLSGKRLSSGFGSGGSGGGGGGGSGGGGGGGSGGGGGGGGGGVGHPLSSLLSIWRGPNVNCVDSTGYTPLHHAALNGHKDVVEVLLRNDALTNVADCKGCYPLHLAAWKGDADIVKLLIHQGPSHTKVNEQNNDNETALHCAAQYGHTEVVKVLLEELTDPTMRNNKFETPLDLAALYGRLEVVKMLLNAHPNLLSCNTKKHTPLHLAARNGHKTVVHVLLDAGMDSNYQTEKGSALHEAALFGKTDVVQILLAAGIDVNIKDNRGLTALDIVRELPSQKSQHIAALIEDYTTGKKSAKAAEKTAQAPPAPTTDPACWIPQGDVEKAVTELIIDFDVNPEEESPYEALYNATSCHSLDSLASGRSSDRESVNKEVEAAGLKAAGVRPRERPPPPAKPPPDEEEEQHTEKMGHGASCEATVARGKSRGSGAEEEEHPYELLLTAETKKPVAVDRKTKDHRRSSGGRSQDPADPQDIQVPEQFSGLLHGSSPICEISEDPFRLVPSAEKGGVEAASHPPAMQLEDADLPASASAPTGSPDQNQKAIYATVQHTHSNRADPETVGTPHVLQHPGGAEDEGDRGGAAGRAHPGSKPKAELKLSRSLSKSDSDLLTCSPTEDDAMGSRSESLSNCSTGKKRLEKSPSFASEWDEIEKIMSSIGEGIDFSQEQQRISGSRMLEQSVGEWLESIGLQQYESKLLLNGFDDVRFLGCNVMEDQDLRDIGIGDPQHRRKLLQAARSLPKLKPLGCDGNSQPSVPAWLDSLGLQDYIQSFLSSGYSSIDTVKNLWELEIVNVLKVNLLGHRKRIIASLADRPYEEPPAKPPRFSQLRCQDLMSQTSSPLSQNDSCTGRSADLLLPSGDSGKRQHERGSELATYSKVERYKAQEDRRESKLTLRPPSLAAPYAPVQNWQHQPEKLIFESCGYEANYLGSMLIKDLRGTESTQDACAKMRKSTEHMKKIPTIILSITYKGVKFIDASNKNVIAEHEIRNISCAAQDPEDLCTFAYITKDLQTSHHYCHVFSTVDVNLTYEIILTLGQAFEVAYQLALQAQRAKPPGAAAGETIETKSSKPVPKPRAGMRKSAVPLPPDTRCCYCHTCTTHRPSYLPLQSVSPGAKLEPPEMDQDSQSHASVSWVVDPKQDSKRTLSTN", "length": 1167, "header": "tr|A0A8V1A543-1|A0A8V1A543_CHICK Isoform 1 of Ankyrin repeat and sterile alpha motif domain containing 1A OS=Gallus gallus OX=9031 GN=ANKS1A PE=1 SV=1 CANONICAL=A0A8V1A543-1" }, "locus": { "chromosome": "26", "start_pos": 4312353, "end_pos": 4229879, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063433.1", "url": "https://www.ensembl.org/id/ENSGALT00010063433.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039156.1", "url": "https://www.ensembl.org/id/ENSGALP00010039156.1" } ] } }, { "isoform_ac": "A0A8V1A7F0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A543/entry#A0A8V1A7F0-1", "sequence": { "sequence": "MSIWRGPNVNCVDSTGYTPLHHAALNGHKDVVEVLLRNDALTNVADCKGCYPLHLAAWKGDADIVKLLIHQGPSHTKVNEQNALEIKELKKYGPFDPYINAKNNDNETALHCAAQYGHTEVVKVLLEELTDPTMRNNKFETPLDLAALYGRLEVVKMLLNAHPNLLSCNTKKHTPLHLAARNGHKTVVHVLLDAGMDSNYQTEKGSALHEAALFGKTDVVQILLAAGIDVNIKDNRGLTALDIVRELPSQKSQHIAALIEDYTTGKKSAKAAEKTAQAPPAPTTDPACWIPQGDVEKAVTELIIDFDVNPEEESPYEALYNATSCHSLDSLASGRSSDRESVNKEVEAAGLKAAGVRPRERPPPPAKPPPDEEEEQHTEKMGHGASCEATVARGKSRGSGAEEEEHPYELLLTAETKKPVAVDRKTKDHRRSSGGRSQDPADPQDIQVPEQFSGLLHGSSPICEISEDPFRLVPSAEKGGVEAASHPPAMQLEDADLPASASAPTGSPDQNQKAIYATVQHTHSNRADPETVGTPHVLQHPGGAEDEGDRGGAAGRAHPGSKPKAELKLSRSLSKSDSDLLTCSPTEDDAMGSRSESLSNCSTGKKRLEKSPSFASEWDEIEKIMSSIGEGIDFSQEQQRISGSRMLEQSVGEWLESIGLQQYESKLLLNGFDDVRFLGCNVMEDQDLRDIGIGDPQHRRKLLQAARSLPKLKPLGCDGNSQPSVPAWLDSLGLQDYIQSFLSSGYSSIDTVKNLWELEIVNVLKVNLLGHRKRIIASLADRPYEEPPAKPPRFSQLRCQDLMSQTSSPLSQNDSCTGRSADLLLPSGDSGKRQHERGSELATYSKVERYKAQEDRRESKLTLRPPSLAAPYAPVQNWQHQPEKLIFESCGYEANYLGSMLIKDLRGTESTQDACAKMRKSTEHMKKIPTIILSITYKGVKFIDASNKNVIAEHEIRNISCAAQDPEDLCTFAYITKDLQTSHHYCHVFSTVDVNLTYEIILTLGQAFEVAYQLALQAQRAKPPGAAAGETIETKSSKPVPKPRAGMRKSALEPPEMDQDSQSHASVSWVVDPKQDSKRTLSTN", "length": 1084, "header": "tr|A0A8V1A7F0-1|A0A8V1A7F0_CHICK Computationally mapped isoform of Ankyrin repeat and sterile alpha motif domain containing 1A OS=Gallus gallus OX=9031 GN=ANKS1A PE=1 SV=1 CANONICAL=A0A8V1A543-1" }, "locus": { "chromosome": "26", "start_pos": 4308457, "end_pos": 4229879, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063420.1", "url": "https://www.ensembl.org/id/ENSGALT00010063420.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039148.1", "url": "https://www.ensembl.org/id/ENSGALP00010039148.1" } ] } }, { "isoform_ac": "A0A8V1A7G3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A543/entry#A0A8V1A7G3-1", "sequence": { "sequence": "MGKEQELLEAARTGNLPAVEKLLSGKRLSSGFGSGGSGGGGGGGSGGGGGGGSGGGGGGGGGGVGHPLSSLLSIWRGPNVNCVDSTGYTPLHHAALNGHKDVVEVLLRNDALTNVADCKGCYPLHLAAWKGDADIVKLLIHQGPSHTKVNEQNALEIKELKKYGPFDPYINAKNNDNETALHCAAQYGHTEVVKVLLEELTDPTMRNNKFETPLDLAALYGRLEVVKMLLNAHPNLLSCNTKKHTPLHLAARNGHKTVVHVLLDAGMDSNYQTEKGSALHEAALFGKTDVVQILLAAGIDVNIKDNRGLTALDIVRELPSQKSQHIAALIEDYTTGKKSAKAAEKTAQAPPAPTTDPACWIPQGDVEKAVTELIIDFDVNPEEESPYEALYNATSCHSLDSLASGRSSDRESVNKEVEAAGLKAAGVRPRERPPPPAKPPPDEEEEQHTEKMGHGASCEATVARGKSRGSGAEEEEHPYELLLTAETKKPVAVDRKTKDHRRSSGGRSQDPADPQDIQVPEQFSGLLHGSSPICEISEDPFRLVPSAEKGGVEAASHPPAMQLEDADLPASASAPTGSPDQNQKAIYATVQHTHSNRADPETVGTPHVLQHPGGAEDEGDRGGAAGRAHPGSKPKAELKLSRSLSKSDSDLLTCSPTEDDAMGSRSESLSNCSTGKKRLEKSPSFASEWDEIEKIMSSIGEGIDFSQEQQRISGSRMLEQSVGEWLESIGLQQYESKLLLNGFDDVRFLGCNVMEDQDLRDIGIGDPQHRRKLLQAARSLPKLKPLGCDGNSQPSVPAWLDSLGLQDYIQSFLSSGYSSIDTVKNLWELEIVNVLKVNLLGHRKRIIASLADRPYEEPPAKPPRFSQLRCQDLMSQTSSPLSQNDSCTGRSADLLLPSGDSGKRQHERGSELATYSKVERYKAQEDRRESKLTLRPPSLAAPYAPVQNWQHQPEKLIFESCGYEANYLGSMLIKDLRGTESTQDACAKMRKSTEHMKKIPTIILSITYKGVKFIDASNKNVIAEHEIRNISCAAQDPEDLCTFAYITKDLQTSHHYCHVFSTVDVNLTYEIILTLGQAFEVAYQLALQAQRAKPPGAAAGETIETKSSKPVPKPRAGMRKSALEPPEMDQDSQSHASVSWVVDPKQDSKRTLSTN", "length": 1155, "header": "tr|A0A8V1A7G3-1|A0A8V1A7G3_CHICK Computationally mapped isoform of Ankyrin repeat and sterile alpha motif domain containing 1A OS=Gallus gallus OX=9031 GN=ANKS1A PE=1 SV=1 CANONICAL=A0A8V1A543-1" }, "locus": { "chromosome": "26", "start_pos": 4312353, "end_pos": 4229879, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063436.1", "url": "https://www.ensembl.org/id/ENSGALT00010063436.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039158.1", "url": "https://www.ensembl.org/id/ENSGALP00010039158.1" } ] } }, { "isoform_ac": "A0A8V1ACF3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A543/entry#A0A8V1ACF3-1", "sequence": { "sequence": "MGKEQELLEAARTGNLPAVEKLLSGKRLSSGFGSGGSGGGGGVGHPLSSLLSIWRGPNVNCVDSTGYTPLHHAALNGHKDVVEVLLRNDALTNVADCKGCYPLHLAAWKGDADIVKLLIHQGPSHTKVNEQNNDNETALHCAAQYGHTEVVKVLLEELTDPTMRNNKFETPLDLAALYGRLEVVKMLLNAHPNLLSCNTKKHTPLHLAARNGHKTVVHVLLDAGMDSNYQTEKGSALHEAALFGKTDVVQILLAAGIDVNIKDNRGLTALDIVRELPSQKSQHIAALIEDYTTGKKSAKAAEKTAQAPPAPTTDPACWIPQGDVEKAVTELIIDFDVNPEEESPYEALYNATSCHSLDSLASGRSSDRESVNKEVEAAGLKAAGVRPRERPPPPAKPPPDEEEEQHTEKMGHGASCEATVARGKSRGSGAEEEEHPYELLLTAETKKPVAVDRKTKDHRRSSGGRSQDPADPQDIQVPEQFSGLLHGSSPICEISEDPFRLVPSAEKGGVEAASHPPAMQLEDADLPASASAPTGSPDQNQKAIYATVQHTHSNRADPETVGTPHVLQHPGGAEDEGDRGGAAGRAHPGSKPKAELKLSRSLSKSDSDLLTCSPTEDDAMGSRSESLSNCSTGKKRLEKSPSFASEWDEIEKIMSSIGEGIDFSQEQQRISGSRMLEQSVGEWLESIGLQQYESKLLLNGFDDVRFLGCNVMEDQDLRDIGIGDPQHRRKLLQAARSLPKLKPLGCDGNSQPSVPAWLDSLGLQDYIQSFLSSGYSSIDTVKNLWELEIVNVLKVNLLGHRKRIIASLADRPYEEPPAKPPRFSQLRCQDLMSQTSSPLSQNDSCTGRSADLLLPSGDSGKRQHERGSELATYSKVERYKAQEDRRESKLTLRPPSLAAPYAPVQNWQHQPEKLIFESCGYEANYLGSMLIKDLRGTESTQDACAKMRKSTEHMKKIPTIILSITYKGVKFIDASNKNVIAEHEIRNISCAAQDPEDLCTFAYITKDLQTSHHYCHVFSTVDVNLTYEIILTLGQAFEVAYQLALQAQRAKPPGAAAGETIETKSSKPVPKPRAGMRKSALEPPEMDQDSQSHASVSWVVDPKQDSKRTLSTKYETTIF", "length": 1119, "header": "tr|A0A8V1ACF3-1|A0A8V1ACF3_CHICK Computationally mapped isoform of Ankyrin repeat and sterile alpha motif domain containing 1A OS=Gallus gallus OX=9031 GN=ANKS1A PE=1 SV=1 CANONICAL=A0A8V1A543-1" }, "locus": { "chromosome": "26", "start_pos": 4312353, "end_pos": 4232746, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063416.1", "url": "https://www.ensembl.org/id/ENSGALT00010063416.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039145.1", "url": "https://www.ensembl.org/id/ENSGALP00010039145.1" } ] } }, { "isoform_ac": "A0A8V1ACG3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A543/entry#A0A8V1ACG3-1", "sequence": { "sequence": 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"publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A536-1", "uniprot_ac": "A0A8V1A536", "uniprot_id": "A0A8V1A536_CHICK", "mass": { "chemical_mass": 44456.0, "monoisotopic_mass": 44456.0 }, "refseq": {}, "gene_names": [ { "name": "GRASP", "type": "recommended", "evidence": [ { "id": "A0A8V1A536", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A536" } ] } ], "protein_names": [ { "name": "Trafficking regulator and scaffold protein tamalin", "type": "synonym", "evidence": [ { "id": "A0A8V1A536", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A536/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A536", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A536" } ], 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"type": "recommended", "evidence": [ { "id": "A0A8V1A568", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A568" } ] } ], "protein_names": [ { "name": "Potassium channel tetramerization domain containing 19", "type": "synonym", "evidence": [ { "id": "A0A8V1A568", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A568/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A568", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A568" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "KCTD19", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A568", "locus": {} } ], "crossref": [ { "id": "A0A8V1A568", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A568", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd18374", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18374", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR011333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A568", "url": "https://www.orthodb.org/?gene=A0A8V1A568", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14499", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14499", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14499:SF20", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14499:SF20", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A568", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A568", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A568-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A568-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MALGLLQHYPDSALGQLLVGSDLARHRLHVCGSGVLFQHAKNWLGTCRLPLTENISEIQELCTYLDKGDITYEPMKEALKCYLKQQMPSESGDCNADWTAEVSVCTLRQIVKVYVGSNWYETYLQTLLKYPELLSNDKKVCWITYGQSLLIHGDGQMFRHVLNFLRLGKLFLPVEFKEWPLFCQEAEEYRIPSLLEALYHCDAYRLWIQNKELRDEDSFPCRVPWNEEHEFSKDPREVYSRAAVDSSKHIDTRSNIKDLKGKRDSNGGKAKPPKTVPQIGGTKRKNAAGGYHESSPSTVKSSLHLESPPRKRGMRSSLRKQAENKDSAIDVPKLLSLVKEWGTLNSKRWNSQHVKVSDGCVTGSVPPHGTPEQDRSVKASITCSAGKMSFAIQENEPKCGAEEKQLEQDVTKHSLPVTPSTGMHQFNTIKTTLPTGKGIRNISRDLAEGSPAGEGRDRSLQMEPGARTGEPRDGHCTKTLQEAHRNVGVILKVEHPPVIGSDGCHMWHEESIVYSTLLGGIELEKSNPQGLPQDTLFLCFALSHEEMFYAKKCHFFLTDVILDSIRLKDPKEITAKVTALVNRLWTQQITPKEFVGDLLSTEYFKGDSIREQLLKWVEFTLPLAWKYSRCLHLLIQRGFARSVSSFTLGM", "length": 650, "header": "tr|A0A8V1A568-1|A0A8V1A568_CHICK Isoform 1 of Potassium channel tetramerization domain containing 19 OS=Gallus gallus OX=9031 GN=KCTD19 PE=4 SV=1 CANONICAL=A0A8V1A568-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A568-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A568/entry#A0A8V1A568-1", "sequence": { "sequence": "MALGLLQHYPDSALGQLLVGSDLARHRLHVCGSGVLFQHAKNWLGTCRLPLTENISEIQELCTYLDKGDITYEPMKEALKCYLKQQMPSESGDCNADWTAEVSVCTLRQIVKVYVGSNWYETYLQTLLKYPELLSNDKKVCWITYGQSLLIHGDGQMFRHVLNFLRLGKLFLPVEFKEWPLFCQEAEEYRIPSLLEALYHCDAYRLWIQNKELRDEDSFPCRVPWNEEHEFSKDPREVYSRAAVDSSKHIDTRSNIKDLKGKRDSNGGKAKPPKTVPQIGGTKRKNAAGGYHESSPSTVKSSLHLESPPRKRGMRSSLRKQAENKDSAIDVPKLLSLVKEWGTLNSKRWNSQHVKVSDGCVTGSVPPHGTPEQDRSVKASITCSAGKMSFAIQENEPKCGAEEKQLEQDVTKHSLPVTPSTGMHQFNTIKTTLPTGKGIRNISRDLAEGSPAGEGRDRSLQMEPGARTGEPRDGHCTKTLQEAHRNVGVILKVEHPPVIGSDGCHMWHEESIVYSTLLGGIELEKSNPQGLPQDTLFLCFALSHEEMFYAKKCHFFLTDVILDSIRLKDPKEITAKVTALVNRLWTQQITPKEFVGDLLSTEYFKGDSIREQLLKWVEFTLPLAWKYSRCLHLLIQRGFARSVSSFTLGM", "length": 650, "header": "tr|A0A8V1A568-1|A0A8V1A568_CHICK Isoform 1 of Potassium channel tetramerization domain containing 19 OS=Gallus gallus OX=9031 GN=KCTD19 PE=4 SV=1 CANONICAL=A0A8V1A568-1" }, "locus": { "chromosome": "11", "start_pos": 1266717, "end_pos": 1259006, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010059665.1", "url": "https://www.ensembl.org/id/ENSGALT00010059665.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036445.1", "url": "https://www.ensembl.org/id/ENSGALP00010036445.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 418, "start_aa": "Thr", "end_pos": 418, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr418", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], 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[] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": 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"snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A583-1", "uniprot_ac": "A0A8V1A583", "uniprot_id": "A0A8V1A583_CHICK", "mass": { "chemical_mass": 30421.0, "monoisotopic_mass": 30421.0 }, "refseq": { "ac": "XP_001234392", "name": "somatomedin-B and thrombospondin type-1 domain-containing protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001234392" }, "gene_names": [ { "name": "RPESL", "type": "recommended", "evidence": [ { "id": "A0A8V1A583", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A583" } ] }, { "name": "RPESL", "type": "synonym", "evidence": [ { "id": "XP_001234392", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001234392" } ] } ], "protein_names": [ { "name": "SMB domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8V1A583", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A583/entry#names_and_taxonomy" } ] }, { "name": "somatomedin-B and thrombospondin type-1 domain-containing protein", "type": "synonym", "evidence": [ { "id": "XP_001234392", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001234392" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052551.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_001234392.3. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_001234392", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001234392" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A583", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A583" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RPESL", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A583", "locus": {} } ], "crossref": [ { "id": "A0A8V1A583", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A583", "database": "AlphaFoldDB", "categories": [] }, { "id": "771089", "url": "https://www.ncbi.nlm.nih.gov/gene/771089", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000884", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000884", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001212", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001212", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036383", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036383", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039942", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039942", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044004", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044004", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056801", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056801", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:771089", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:771089", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GYCVQFQ", "url": "https://omabrowser.org/oma/group/GYCVQFQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A583", "url": "https://www.orthodb.org/?gene=A0A8V1A583", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR20920", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR20920", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR20920:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR20920:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF19028", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19028", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25031", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25031", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_001234392", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001234392", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1A583", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A583", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A583-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A583-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPRCPGRAAALPPPPPPPPALLLLLLLLLPAPRPAAAGCAALGLCCPGRTPSCRSTGWRPDGSYGPCYCDQACEHTLDCCHDYSQACPVIPCVVSQWSAWSGCAEPCKTTYRVRRRHIIQEPRNGGEACPALEERAGCVEYWTEQGTECKQSLIPAFITTGGFGKARKKRAATDGRERVGYCVEFQLVAITQGCLHSHHSYTHWMQYLREGHTVCVECQHPALDSESLHCYGDGSGSQRNQLLHWQAVGNPRCSGTWKRIRQLDTCSCPSVHSFLFI", "length": 277, "header": "tr|A0A8V1A583-1|A0A8V1A583_CHICK Isoform 1 of SMB domain-containing protein OS=Gallus gallus OX=9031 GN=RPESL PE=1 SV=1 CANONICAL=A0A8V1A583-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A583-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A583/entry#A0A8V1A583-1", "sequence": { "sequence": "MPRCPGRAAALPPPPPPPPALLLLLLLLLPAPRPAAAGCAALGLCCPGRTPSCRSTGWRPDGSYGPCYCDQACEHTLDCCHDYSQACPVIPCVVSQWSAWSGCAEPCKTTYRVRRRHIIQEPRNGGEACPALEERAGCVEYWTEQGTECKQSLIPAFITTGGFGKARKKRAATDGRERVGYCVEFQLVAITQGCLHSHHSYTHWMQYLREGHTVCVECQHPALDSESLHCYGDGSGSQRNQLLHWQAVGNPRCSGTWKRIRQLDTCSCPSVHSFLFI", "length": 277, "header": "tr|A0A8V1A583-1|A0A8V1A583_CHICK Isoform 1 of SMB domain-containing protein OS=Gallus gallus OX=9031 GN=RPESL PE=1 SV=1 CANONICAL=A0A8V1A583-1" }, "locus": { "chromosome": "20", "start_pos": 6840585, "end_pos": 6831206, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010059686.1", "url": "https://www.ensembl.org/id/ENSGALT00010059686.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036460.1", "url": "https://www.ensembl.org/id/ENSGALP00010036460.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:771089", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:771089", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8M9Q935-1", "protein_name": "Somatomedin-B and thrombospondin type-1 domain-containing protein", "gene_name": "si:dkey-7k24.5", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSCSDEASDTFRLLIIMSACSSWMVFCFLALLVTLVSQSEGGCQDTGMCCIGQNQSCISEDWRKDRSFGECYCDQACKTTLDCCHDYDLACPAVSCVVSEWSLWSGCLEPCKPTLRSRRRQVIQEARNGGEPCPSLQQTAGCAEYHDQHGPCLQSLVPALITTGGYGNARKKREVLDNITGYCVEFELTSLTAGCQRSFSSHTRWMRYLKEGHQVCVECQPPALTPGQRYCSGDGENMGYDRSVSLQWQAVGNSQCRGVWRRVRRRESCSCPTVHSFLFI", "length": 280 }, "evidence": [ { "id": "A0A8V1A583", "url": "https://omabrowser.org/oma/group/A0A8V1A583/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1A583", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A583" }, { "id": "PS50958", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50958" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SMB", "eco_id": "ECO_0000259", "start_pos": 49, "end_pos": 92, "start_aa": "Arg", "end_aa": "Cys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A5A0-1", "uniprot_ac": "A0A8V1A5A0", "uniprot_id": "A0A8V1A5A0_CHICK", "mass": { "chemical_mass": 28887.0, "monoisotopic_mass": 28887.0 }, "refseq": { "ac": "XP_040501946", "name": "exosome complex component MTR3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040501946" }, "gene_names": [ { "name": "EXOSC6", "type": "recommended", "evidence": [ { "id": "A0A8V1A5A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5A0" } ] }, { "name": "EXOSC6", "type": "synonym", "evidence": [ { "id": "XP_040501946", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040501946" } ] } ], "protein_names": [ { "name": "Exosome component 6", "type": "synonym", "evidence": [ { "id": "A0A8V1A5A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5A0/entry#names_and_taxonomy" } ] }, { "name": "exosome complex component MTR3", "type": "synonym", "evidence": [ { "id": "XP_040501946", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040501946" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052542.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040501946", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040501946" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A5A0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5A0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "EXOSC6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5A0", "locus": { "chromosome": "11", "start_pos": 1208173, "end_pos": 1207334, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010025438", "url": "https://www.ensembl.org/id/ENSGALG00010025438" } ] } } ], "crossref": [ { "id": "A0A8V1A5A0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A5A0", "database": "AlphaFoldDB", "categories": [] }, { "id": "107052160", "url": "https://www.ncbi.nlm.nih.gov/gene/107052160", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001247", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001247", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020568", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020568", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027408", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027408", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036345", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036345", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050080", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050080", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "MCCVYGP", "url": "https://omabrowser.org/oma/group/MCCVYGP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A5A0", "url": "https://www.orthodb.org/?gene=A0A8V1A5A0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11953", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11953", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11953:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11953:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01138", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01138", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-429958", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-429958", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-450385", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-450385", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-6791226", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6791226", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9930044", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9930044", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_040501946", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040501946", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1A5A0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5A0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A5A0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5A0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPLDHRRLRGPDESQPPELWAAQPRDGGGGEAEESGAAPRDPCALRPLFARAGLLSQAEGSAYVELSGGTKVLCAAWGPREAAEPGGAVAAGRLLCDFRRAPFCARGARPRPGGAAEREAEREAAAALREALEPAVRLSRYPRARLAVSALLLQDGGSALAAAISAASLALADAGVEMYDLAVGCALCRPPRGDGDGDGSAAEPWLLQPGEAEERGSAARLTVALLPALNQVSAVLGGGRGGEPEGWGRALRLGVEGCQRLYPVLRHCLLRAARRRDGA", "length": 279, "header": "tr|A0A8V1A5A0-1|A0A8V1A5A0_CHICK Isoform 1 of Exosome component 6 OS=Gallus gallus OX=9031 GN=EXOSC6 PE=3 SV=1 CANONICAL=A0A8V1A5A0-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A5A0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5A0/entry#A0A8V1A5A0-1", "sequence": { "sequence": "MPLDHRRLRGPDESQPPELWAAQPRDGGGGEAEESGAAPRDPCALRPLFARAGLLSQAEGSAYVELSGGTKVLCAAWGPREAAEPGGAVAAGRLLCDFRRAPFCARGARPRPGGAAEREAEREAAAALREALEPAVRLSRYPRARLAVSALLLQDGGSALAAAISAASLALADAGVEMYDLAVGCALCRPPRGDGDGDGSAAEPWLLQPGEAEERGSAARLTVALLPALNQVSAVLGGGRGGEPEGWGRALRLGVEGCQRLYPVLRHCLLRAARRRDGA", "length": 279, "header": "tr|A0A8V1A5A0-1|A0A8V1A5A0_CHICK Isoform 1 of Exosome component 6 OS=Gallus gallus OX=9031 GN=EXOSC6 PE=3 SV=1 CANONICAL=A0A8V1A5A0-1" }, "locus": { "chromosome": "11", "start_pos": 1208170, "end_pos": 1207334, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010062103.1", "url": "https://www.ensembl.org/id/ENSGALT00010062103.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038384.1", "url": "https://www.ensembl.org/id/ENSGALP00010038384.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-429958", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-429958", "resource": "Reactome", "description": "mRNA decay by 3' to 5' exoribonuclease" }, { "id": "R-GGA-450385", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-450385", "resource": "Reactome", "description": "Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA" }, { "id": "R-GGA-6791226", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6791226", "resource": "Reactome", "description": "Major pathway of rRNA processing in the nucleolus and cytosol" }, { "id": "R-GGA-9930044", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9930044", "resource": "Reactome", "description": "Nuclear RNA decay" } ], "orthologs": [ { "uniprot_canonical_ac": "A2RVK7-1", "protein_name": "Exosome complex component RRP41-like", "gene_name": "RRP41L", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAAKPGAATPTYSPKIVGRSRLPIFKDSDLDWSRPDGRGFHQCRPALLQTGAVSSASGSAYAEFGNTKVIVSVFGPRESKKAMVYSDVGRLNCNVSYTNFASPTLGQGTDHKEYSSMLHKALEGVIMMETFPKTTVDVFALVLESGGSDLSVLISCASLALADAGIMMYDLITAVSVSCIGKSLMIDPVTEEEGCEDGSFMMTCMPSRYEITQLTITGEWTTPNINEAMQLCLDASSKLGEIMRDCLKQSASASDE", "length": 256 }, "evidence": [ { "id": "A0A8V1A5A0", "url": "https://omabrowser.org/oma/group/A0A8V1A5A0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "D3ZW38-1", "protein_name": "Exosome complex component MTR3", "gene_name": "Exosc6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPGDHRRIRGPEESQPPQLYAAEEDETPAARDPTRLRPVYARAGLLSQAKGSAYLEAGGTKVLCAVSGPRQAEGGERGGGPAGAGGEAPAALRGRLLCDFRRAPFSGRRRRAPQGSSEDRELGLALQEALEPAVRLGRYPRAQLEVSALLLEDGGSALAAALTAAALALADAGVEMYDLVVGCGLSLTPGPSPTWLLDPTRLEEEHSEAGLTVALMPVLNQVAGLLGSGEGGQTESWTDAVRLGLEGCQRLYPVLQQCLVRAARRRGAAAPP", "length": 272 }, "evidence": [ { "id": "A0A8V1A5A0", "url": "https://omabrowser.org/oma/group/A0A8V1A5A0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1S435-1", "protein_name": "Exosome complex component MTR3", "gene_name": "EXOSC6", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPGDHRRIRGPEESQPPQLYAVGEDEEPAARDPTRLRPVYARAGLLSQAKGSAYLEAGGTKVLCAVSGPRQAEGGERGGGPAGTGGEAPAALRGRLLCDFRRAPFSGRRRRAPPGGGEERELALALQEALEPAVRLGRYPRAQLEVSALLLEDGGSALAAALTAAALALADAGIEMYDLVVGCGLSHTPGPAPTWLLDPTLLEEERAAASLTVALMPVLNQVAGLLGSGEGGPTESWAEAVRLGLEGCQRLYPVLQQCLVRAARRRGASAPP", "length": 272 }, "evidence": [ { "id": "A0A8V1A5A0", "url": "https://omabrowser.org/oma/group/A0A8V1A5A0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q55BB0-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKIGVVSQGSGSSYVEMENTKVLCTIHGPRATQKTELFETAKLNCELKYTTFSSTTEKIDYVENSKEKDLSLLISQSIIGSIRLEKYPKTAIDIYILVLNDDGNVLVASITAATMALADAGVEMFDMVSSCSVSCTKDNRTLIDPTTLEETIPSSSTVLVAKMPSLNEITQIIQTGELQYTNVLECVDLCIDGCDKIYSIMKQNLIDSLLQKQQQQK", "length": 217 }, "evidence": [ { "id": "A0A8V1A5A0", "url": "https://omabrowser.org/oma/group/A0A8V1A5A0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q5RKV6-1", "protein_name": "Exosome complex component MTR3", "gene_name": "EXOSC6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPGDHRRIRGPEESQPPQLYAADEEEAPGTRDPTRLRPVYARAGLLSQAKGSAYLEAGGTKVLCAVSGPRQAEGGERGGGPAGAGGEAPAALRGRLLCDFRRAPFAGRRRRAPPGGCEERELALALQEALEPAVRLGRYPRAQLEVSALLLEDGGSALAAALTAAALALADAGVEMYDLVVGCGLSLAPGPAPTWLLDPTRLEEERAAAGLTVALMPVLNQVAGLLGSGEGGLTESWAEAVRLGLEGCQRLYPVLQQSLVRAARRRGAAAQP", "length": 272 }, "evidence": [ { "id": "A0A8V1A5A0", "url": "https://omabrowser.org/oma/group/A0A8V1A5A0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6P0I8-1", "protein_name": "Exosome complex component MTR3", "gene_name": "exosc6", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MPVDTKRIRGPEESQSPLLFLSPDKAPKAPSSRQGVRGNGDVRPVFARCGLVSQAKGSAYIEAGNTKIICSVYGPKETERRDETDMKTGRLVCDFRLAPFSCVKRGAWIQGSEERDLSATLMESLRPGVCLHRYPRSQIDVNVMVLENDGSVLAHAVTCASMALADAGIEMYDIVLGCTLRQSGNACLVDPSYAEECGSWQEGYGDNQGCVTLALLPNLNQVSGLNADGEMREDTLTEAMRTCMDGCHKLYPVVQQALTRAVKKKAPPPEK", "length": 271 }, "evidence": [ { "id": "A0A8V1A5A0", "url": "https://omabrowser.org/oma/group/A0A8V1A5A0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8BTW3-1", "protein_name": "Exosome complex component MTR3", "gene_name": "Exosc6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPGDHRRIRGPEESQPPQLYAAEDDETPAARDPTRLRPVYARAGLLSQAKGSAYLEAGGTKVLCAVSGPRQAEGGERGSGPAGAGGEAPAALRGRLLCDFRRAPFSGRRRRAPQGGGGEDRELGLALQEALEPAVRLGRYPRAQLEVSALLLEDGGCALAAALTAAALALADAGVEMYDLVVGCGLSLTPGPSPTWLLDPTRLEEEHSAAGLTVALMPVLNQVAGLLGSGEGGQTESWTDAVRLGLEGCQRLYPVLQQCLVRAARRRGAAAPP", "length": 273 }, "evidence": [ { "id": "A0A8V1A5A0", "url": "https://omabrowser.org/oma/group/A0A8V1A5A0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "nuclear mRNA surveillance", "id": "GO:0071028", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071028", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A5A0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5A0" } ], "pmid": "" }, { "name": "rRNA processing", "id": "GO:0006364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006364", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A5A0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5A0" } ], "pmid": "" }, { "name": "rRNA catabolic process", "id": "GO:0016075", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016075", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A5A0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5A0" } ], "pmid": "" }, { "name": "U4 snRNA 3'-end processing", "id": "GO:0034475", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034475", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A5A0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5A0" } ], "pmid": "" }, { "name": "DNA deamination", "id": "GO:0045006", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045006", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A5A0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5A0" } ], "pmid": "" }, { "name": "poly(A)-dependent snoRNA 3'-end processing", "id": "GO:0071051", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071051", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A5A0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5A0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A5A0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5A0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A5A0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5A0" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A5A0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5A0" } ], "pmid": "" }, { "name": "nuclear exosome (RNase complex)", "id": "GO:0000176", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000176", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A5A0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5A0" } ], "pmid": "" }, { "name": "cytoplasmic exosome (RNase complex)", "id": "GO:0000177", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000177", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A5A0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5A0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1A5A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5A0" }, { "id": "PF01138", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01138" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Exoribonuclease phosphorolytic", "eco_id": "ECO_0000259", "start_pos": 45, "end_pos": 177, "start_aa": "Leu", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A5A3-1", "uniprot_ac": "A0A8V1A5A3", "uniprot_id": "A0A8V1A5A3_CHICK", "mass": { "chemical_mass": 41887.0, "monoisotopic_mass": 41887.0 }, "refseq": {}, "gene_names": [ { "name": "LOC100857333", "type": "recommended", "evidence": [ { "id": "A0A8V1A5A3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5A3" } ] } ], "protein_names": [ { "name": "LRRCT domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8V1A5A3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5A3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A5A3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5A3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC100857333", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5A3", "locus": {} } ], "crossref": [ { "id": "A0A8V1A5A3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A5A3", "database": "AlphaFoldDB", "categories": [] }, { "id": "100857333", "url": "https://www.ncbi.nlm.nih.gov/gene/100857333", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000483", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000483", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003591", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003591", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050541", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050541", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:100857333", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100857333", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HYEESTL", "url": "https://omabrowser.org/oma/group/HYEESTL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ACX9", "url": "https://www.orthodb.org/?gene=A0A8V1ACX9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24369", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24369", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24369:SF157", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24369:SF157", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00560", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00560", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13855", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13855", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1A5A3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5A3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A5A3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5A3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ACX9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACX9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ACX9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACX9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFJ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFJ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFJ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFJ6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRRIQLCPAHQPGCRPQAVRFPALLPLILAALQPAAVPTEPPPPCPWEMNKVKDIVEVNCTGQDLGAVPVSLPEDTGILLLNANRLLSVSTAAFQTLPEDTGILLLNANRLLFISTATFQTLPALQVLDLSDNGLQAVLTEAALPSLKELLLSRNALEALPALQGLPALTRLALAHNKLQALAPAAFRAVLQLQDLDLRGNALRTLPEDVFMGLRALKDLDLSDNALEELPRGLLQDLVTLETLWLSGNRLRALPSGFFPEGHLFAYVFLTENPWHCDCDLVYLRSWILRNEGSVYEPERGLGKTKVEVAPEKVLCQSPSEHLQKPIIRFKPNCGHVGDAEEEEEYEFHYEESTLIYPLLASLSPVYPPSSEEPTTAPHTP", "length": 381, "header": "tr|A0A8V1A5A3-1|A0A8V1A5A3_CHICK Isoform 1 of LRRCT domain-containing protein OS=Gallus gallus OX=9031 GN=LOC100857333 PE=1 SV=1 CANONICAL=A0A8V1A5A3-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A5A3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5A3/entry#A0A8V1A5A3-1", "sequence": { "sequence": "MRRIQLCPAHQPGCRPQAVRFPALLPLILAALQPAAVPTEPPPPCPWEMNKVKDIVEVNCTGQDLGAVPVSLPEDTGILLLNANRLLSVSTAAFQTLPEDTGILLLNANRLLFISTATFQTLPALQVLDLSDNGLQAVLTEAALPSLKELLLSRNALEALPALQGLPALTRLALAHNKLQALAPAAFRAVLQLQDLDLRGNALRTLPEDVFMGLRALKDLDLSDNALEELPRGLLQDLVTLETLWLSGNRLRALPSGFFPEGHLFAYVFLTENPWHCDCDLVYLRSWILRNEGSVYEPERGLGKTKVEVAPEKVLCQSPSEHLQKPIIRFKPNCGHVGDAEEEEEYEFHYEESTLIYPLLASLSPVYPPSSEEPTTAPHTP", "length": 381, "header": "tr|A0A8V1A5A3-1|A0A8V1A5A3_CHICK Isoform 1 of LRRCT domain-containing protein OS=Gallus gallus OX=9031 GN=LOC100857333 PE=1 SV=1 CANONICAL=A0A8V1A5A3-1" }, "locus": { "chromosome": "28", "start_pos": 1214140, "end_pos": 1212482, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067185.1", "url": "https://www.ensembl.org/id/ENSGALT00010067185.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041089.1", "url": "https://www.ensembl.org/id/ENSGALP00010041089.1" } ] } }, { "isoform_ac": "A0A8V1ACX9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5A3/entry#A0A8V1ACX9-1", "sequence": { "sequence": "MAVRFPALLPLILAALQPAAVPTEPPPPCPWEMNKVKDIVEVNCTGQDLGAVPVSLPEDTGILLLNANRLLSVSTAAFQTLPEDTGILLLNANRLLFISTATFQTLPALQVLDLSDNGLQAVLTEAALPSLKELLLSRNALEALPALQGLPALTRLALAHNKLQALAPAAFRAVLQLQDLDLRGNALRTLPEDVFMGLRALKDLDLSDNALEELPRGLLQDLVTLETLWLSGNRLRALPSGFFPEGHLFAYVFLTENPWHCDCDLVYLRSWILRNEGSVYEPERGLGKTKVEVAPEKVLCQSPSEHLQKPIIRFKPNCGHVGDAEEEEEYEFHYEESTLIYPLLASLSPVYPPSSEEPTTAPHTP", "length": 365, "header": "tr|A0A8V1ACX9-1|A0A8V1ACX9_CHICK Computationally mapped isoform of LRRCT domain-containing protein OS=Gallus gallus OX=9031 GN=LOC100857333 PE=1 SV=1 CANONICAL=A0A8V1A5A3-1" }, "locus": { "chromosome": "28", "start_pos": 1213692, "end_pos": 1212482, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067184.1", "url": "https://www.ensembl.org/id/ENSGALT00010067184.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041088.1", "url": "https://www.ensembl.org/id/ENSGALP00010041088.1" } ] } }, { "isoform_ac": "A0A8V1AFJ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5A3/entry#A0A8V1AFJ6-1", "sequence": { "sequence": "MAVRFPALLPLILAALQPAAVPTEPPPPCPWEMNKVKDIVEVNCTGQDLGAVPVSLPEDTGILLLNANRLLSVSTAAFQTLPEDTGILLLNANRLLFISTATFQTLPALQGLPALTRLALAHNKLQALAPAAFRAVLQLQDLDLRGNALRTLPEDVFMGLRALKDLDLSDNALEELPRGLLQDLVTLETLWLSGNRLRALPSGFFPEGHLFAYVFLTENPWHCDCDLVYLRSWILRNEGSVYEPERGLGKTKVEVAPEKVLCQSPSEHLQKPIIRFKPNCGHVGDAEEEEEYEFHYEESTLIYPLLASLSPVYPPSSEEPTTAPHTP", "length": 327, "header": "tr|A0A8V1AFJ6-1|A0A8V1AFJ6_CHICK Computationally mapped isoform of LRRCT domain-containing protein OS=Gallus gallus OX=9031 GN=LOC100857333 PE=1 SV=1 CANONICAL=A0A8V1A5A3-1" }, "locus": { "chromosome": "28", "start_pos": 1213692, "end_pos": 1212482, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067183.1", "url": "https://www.ensembl.org/id/ENSGALT00010067183.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041087.1", "url": "https://www.ensembl.org/id/ENSGALP00010041087.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:100857333", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100857333", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A5A3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5A3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 59, "end_pos": 61, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1A5A3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5A3" }, { "id": "SM00082", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00082" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "LRRCT", "eco_id": "ECO_0000259", "start_pos": 273, "end_pos": 335, "start_aa": "Asn", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 59, "end_pos": 61 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A5B2-1", "uniprot_ac": "A0A8V1A5B2", "uniprot_id": "A0A8V1A5B2_CHICK", "mass": { "chemical_mass": 59407.0, "monoisotopic_mass": 59407.0 }, "refseq": {}, "gene_names": [ { "name": "ADGRG5", "type": "recommended", "evidence": [ { "id": "A0A8V1A5B2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5B2" } ] } ], "protein_names": [ { "name": "Adhesion G protein-coupled receptor G5", "type": "synonym", "evidence": [ { "id": "A0A8V1A5B2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5B2/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A5B2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5B2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ADGRG5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5B2", "locus": { "chromosome": "11", "start_pos": 529576, "end_pos": 533493, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010024488", "url": "https://www.ensembl.org/id/ENSGALG00010024488" } ] } } ], "crossref": [ { "id": "A0A8V1A5B2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A5B2", "database": "AlphaFoldDB", "categories": [] }, { "id": "415634", "url": "https://www.ncbi.nlm.nih.gov/gene/415634", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000203", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000203", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000832", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000832", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017981", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017981", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046338", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046338", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057244", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057244", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "RIHVNLH", "url": "https://omabrowser.org/oma/group/RIHVNLH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A5B2", "url": "https://www.orthodb.org/?gene=A0A8V1A5B2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A5B6", "url": "https://www.orthodb.org/?gene=A0A8V1A5B6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12011", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12011", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12011:SF326", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12011:SF326", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00002", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00002", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01825", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01825", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1A5B2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5B2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A5B2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5B2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A5B6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5B6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A5B6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5B6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLTLLLAAFVLCLAEAVLPSQGTEYIQSCMHNLTEGLKRGSSRHNWARLTELEQLLAHSTPGKEGYSFKTNMLEAFVFSITAGSFRGLNLSSSMPVRSKGQVSAQLRDSISFPVELMEGMKAQEKQKLICICIRSAGMFLDEHNSSVLNNHILGAFLHNRRVGRLRRPVEIHFRHDKELDSSNATCVFWQPAGTGSAGNWSREGCETQHQKGIVRCLCNHLTYFAVLLIQAHDLSESELQSLTYISTVGCSISAAAALCTLLLCCVFRCRPRDDTTRIHMNLLAALLLLNVSFLLSEPLAAGTTGGCQAAAALLHGSLLCALGWMGAEGFHLYLLLIKVYNIYVRHYLLKLCLCTWGLPTLAVVAVLIFKREIYGHHIISTADGYKNVTMCWLTSPSAHYVTLCYAGLILLFNVLVLVAVVAVLRRTRQQQQQRARKDWMTVLGLTCLLGTTWGTAFCAFGVLLVPQLYLFTVLNSLQGQQPGGILGGGFPHPPGTALRVPMALTVPPPQVCSSAFGTSARTAASAAPTAVPPDSGAAGLASVFSVN", "length": 547, "header": "tr|A0A8V1A5B2-1|A0A8V1A5B2_CHICK Isoform 1 of Adhesion G protein-coupled receptor G5 OS=Gallus gallus OX=9031 GN=ADGRG5 PE=4 SV=1 CANONICAL=A0A8V1A5B2-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A5B2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5B2/entry#A0A8V1A5B2-1", "sequence": { "sequence": "MLTLLLAAFVLCLAEAVLPSQGTEYIQSCMHNLTEGLKRGSSRHNWARLTELEQLLAHSTPGKEGYSFKTNMLEAFVFSITAGSFRGLNLSSSMPVRSKGQVSAQLRDSISFPVELMEGMKAQEKQKLICICIRSAGMFLDEHNSSVLNNHILGAFLHNRRVGRLRRPVEIHFRHDKELDSSNATCVFWQPAGTGSAGNWSREGCETQHQKGIVRCLCNHLTYFAVLLIQAHDLSESELQSLTYISTVGCSISAAAALCTLLLCCVFRCRPRDDTTRIHMNLLAALLLLNVSFLLSEPLAAGTTGGCQAAAALLHGSLLCALGWMGAEGFHLYLLLIKVYNIYVRHYLLKLCLCTWGLPTLAVVAVLIFKREIYGHHIISTADGYKNVTMCWLTSPSAHYVTLCYAGLILLFNVLVLVAVVAVLRRTRQQQQQRARKDWMTVLGLTCLLGTTWGTAFCAFGVLLVPQLYLFTVLNSLQGQQPGGILGGGFPHPPGTALRVPMALTVPPPQVCSSAFGTSARTAASAAPTAVPPDSGAAGLASVFSVN", "length": 547, "header": "tr|A0A8V1A5B2-1|A0A8V1A5B2_CHICK Isoform 1 of Adhesion G protein-coupled receptor G5 OS=Gallus gallus OX=9031 GN=ADGRG5 PE=4 SV=1 CANONICAL=A0A8V1A5B2-1" }, "locus": { "chromosome": "11", "start_pos": 533011, "end_pos": 529707, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010059729.1", "url": "https://www.ensembl.org/id/ENSGALT00010059729.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036490.1", "url": "https://www.ensembl.org/id/ENSGALP00010036490.1" } ] } }, { "isoform_ac": "A0A8V1A5B6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5B2/entry#A0A8V1A5B6-1", "sequence": { "sequence": "MLTLLLAAFVLCLAEAVLPSQGTEYIQSCMHNLTEGLKRGSSRHNWASRLTELEQLLAHSTPGKEGYSFKTNMLEAFVFSITAGSFRGLNLSSSMPVRSKGQVSAQLRDSISFPVELMEGMKAQEKQKLICICIRSAGMFLDEHNSSVLNNHILGAFLHNRRVGRLRRPVEIHFRHDKELDSSNATCVFWQPAGTGSAGNWSREGCETQHQKGIVRCLCNHLTYFAVLLIQAHDLSESELQSLTYISTVGCSISAAAALCTLLLCCVFRCRPRDDTTRIHMNLLAALLLLNVSFLLSEPLAAGTTGGCQAAAALLHGSLLCALGWMGAEGFHLYLLLIKVYNIYVRHYLLKLCLCTWGLPTLAVVAVLIFKREIYGHHIISTADGYKNVTMCWLTSPSAHYVTLCYAGLILLFNVLVLVAVVAVLRRTRQQQQQRARKDWMTVLGLTCLLGTTWGTAFCAFGVLLVPQLYLFTVLNSLQGVFLCFWYLSTHRSKRSSHCSTSR", "length": 503, "header": "tr|A0A8V1A5B6-1|A0A8V1A5B6_CHICK Computationally mapped isoform of Adhesion G protein-coupled receptor G5 OS=Gallus gallus OX=9031 GN=ADGRG5 PE=4 SV=1 CANONICAL=A0A8V1A5B2-1" }, "locus": { "chromosome": "11", "start_pos": 533011, "end_pos": 529747, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010059735.1", "url": "https://www.ensembl.org/id/ENSGALT00010059735.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036495.1", "url": "https://www.ensembl.org/id/ENSGALP00010036495.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A287ANP6-1", "protein_name": "Adhesion G-protein coupled receptor G5", "gene_name": "ADGRG5", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEKMEVAAKKRSLISFADFIHGLEWRLLNVSFGGHNLTLKTHTIQTLAFKLGCNFTGLSLSSDTLERVPQAQARHAMQFPAELTRDACRTHTRELRLICIYFFTSHFFKKDINSSLLNNYVLGAQLGHGPVNNLSDRVNISFWHNQSLESYTVTCVFWKEGASKDYWGAWSPEGCLTEQPSPSQVLCRCNHLTYFAVLMQLSPAPVPATLLAPLLYISLVGCSISIVASLLTVLLQFYARKQSDSTTRIHMNLNSSVLLLNVAFLLSPVWAVPGSACTVLGATLHYMLLSCLTWMAIEGFNLYLLLGRVYNIYFRRYVLKLCAVGWGVPAFLVLLLLATNSSVYGPHRIPLSDSQRNGTDFQNMSICWVRNPDVHSVLVMGYGGLMSLFNLVVLVWALRVLRRLRVQEKPPGPRACRDTVTVLGLTVLLGTTWALAFFSFGVFLLPQLFLFTIFNSFYGFFLFLWFCSQRCRAEAEAEAEMEAFSSSQAMQ", "length": 491 }, "evidence": [ { "id": "A0A8V1A5B2", "url": "https://omabrowser.org/oma/group/A0A8V1A5B2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A3Q1LN02-1", "protein_name": "Adhesion G-protein coupled receptor G5", "gene_name": "ADGRG5", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNCCWAPFLYLCLLVSQSRTAEASQETLHWMEKMEVAAKSRISTSSAELIHGLELRLLNASFGGHNLTLQTQIIQALAFKLNCNFSGLSLSSAALEKVPQARPQHAMQFPAELTRNACRTRSRDLRLICIYFSSTRFFQKDINSSLLNNYVLGAQLSHGYVSNLSEPVNISFWHNQSLEGYTVTCVFWKERASKHHWGAWSPEGCHTEQPTPSQVLCRCNHLTYFAVLMQLSQAPVPAELLAPLTYISLVGCSISIVASLLTVLLHLQARYSPALMQGLLPSAAQNASFFSTWPRENQVGFPGRQKARGAGVEADKPHCVWLLLGPCPSLLTRVPVIMCLRAQGAALPGDIQVAEGHAPTRRKQSDSVTRIHMNLHASVLLLNITFLLSPVLATPPAPGAACVVLAATLHYALLSCLTWMAIEGFNLYLLLGRVYNVYIRRYVLKLCAVGWGVPAFLVLFLLAVKSSVYGPYKIQLSDSHGNSTGFKITSICWVQSSWVHSVLVMGYGGLTSLFNLVVLAWALRVLNKLRAQEKAPGTRACRDTVTVLGLTVLLGTTWALAFFSFSVFLLPQLFLFTIFNSLYGFFLFLWFCSQRCRSEAEAEAEMEVFTSQMVQ", "length": 615 }, "evidence": [ { "id": "A0A8V1A5B2", "url": "https://omabrowser.org/oma/group/A0A8V1A5B2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A9J7FP15-1", "protein_name": "Adhesion G-protein coupled receptor G5", "gene_name": "Adgrg5", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDTQRSLFFCLCILVAQSISQETLLPLLYLMKRLERPMGRALTSKVSPRNIHQLEQMLLNTSFFGHNLTLQTNSIQSLVFKLDCDFSGLSLSSATMANVSQAWAPHAMQFPAELTKDSCVTSRPAELRLICIYFFTAHLFQDDSNSSLLNNYVLGAQLDHRPVNNLQKPINISFWHNQSLEGYTVTCVFWKEGASKHSWGAWSPEGCYTEQPSPSQVLCHCNHLTYFAVLMQLSGDPVPAELQEPLEYISLVGCSISIVASLLTMLLYAHSRKQSDSITRIHMNLHGSVLLLNVTFLLSPQMALPTVPKSVCIALAATLHYALLSCLTWMAIEGYNLYLLLGHVYNVYIHRYLLKLCMLGWGFPALLVLLLLVIKSSVYGPYVISFSNSQDNGTGFQNVSMCWVCSPVVHSVLVMGYGGLMSLFNLVVLTWALWILCRLRIREKALSPWAYRDTVMVLGLTVLLGTTWVLAFFSFSVFRLPQLFLFTIFNSLYGFFLFLWFCLHRCHSDAEAKAEMEAVSSSQMTH", "length": 526 }, "evidence": [ { "id": "A0A8V1A5B2", "url": "https://omabrowser.org/oma/group/A0A8V1A5B2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "F1M644-1", "protein_name": "Adhesion G-protein coupled receptor G5", "gene_name": "Adgrg5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDQHQALFFCLCLLAAQVVLVETLPEILNLMKRLERPIGRALSSRVRFIHHLEQMLLNASFHGHNLTLQTNSIQSLVFKLSCGFPGLSLSSATLTNVSQAWAPHAMQFPAELTKNACVTSRPAELRLICVYFFTAHLFQDDRNSSLLNNYVLGAQLDHRPVNNLQRPVNISFWHNRSLEGYTVTCVFWKEGAGKHSWGAWSPKGCYTEQPSPTQVLCHCNHLTYFAVLMQLSGDPVPTELQTPLEYISLVGCSISIVASLLTILLNAHSRKLSDSTTRIHLNLNGSVLLLNITFLLSSQMVPPTVPRSVCTVLAATLHYALLSSLTWMGVEGFNLYLLLGRVYNVYIRRYLLKLCVLGWGFPALLVLLLLMIKSSVYGPCVISFSKSQENGTGFQNVSMCWVRSPMVHSILVMGYGGLTSLFNLVVLAWALWILCRLRKREKALSPWACRDIVMVLGLTVLLGTTWSLAFFSFSVFLLPQVFLFTIFNSLYGFFLFLWFCSQKRYSDAEAKAVMEAVSFSQMTH", "length": 524 }, "evidence": [ { "id": "A0A8V1A5B2", "url": "https://omabrowser.org/oma/group/A0A8V1A5B2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q3V3Z3-1", "protein_name": "Adhesion G protein-coupled receptor G5", "gene_name": "Adgrg5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDPHGALFFYLCLLAAQVVLVETLSDLLVLMKRLEQPVGRGLSSRARHIHSLEQKLLNASFGGHNLTLQTNSIQSLVFKLSCDFPGLSLSSTTLTNVSQVRAPHAMQFPAELTKGACVTSRPAELRLICIYFFTAHLFQDDRNSSLLNNYVLGAQLDHRPVNNLQKPVNISFWHNRSLEGYTVSCVFWKEGASKSSWGAWSPEGCYTEQPSATQVLCHCNHLTYFAVLMQLSGDPVPAELQVPLEYISFVGCSISIVASLLTILLYAQSRKQSDSTTRIHMNLNGSVLLLNVTFLLSSQMTLPTMPRPVCKVLAAVLHYALLSSLTWMAIEGFNLYLFLGRVYNAYIRRYLLKLCMLGWGFPALLVLLLLMIKSSVYGPCVTSLSKSQENGTGFQNVSMCWIRSPMVHSILVMGYGGFTSLFNLVVLAWALWILCRLRAREKALSPWAYRDTAMVLGLTVLLGTTWTLAFFSFGVFLLPQLFLFTIFNSLYGFFLFLWFCSQKRYSDAEAKAEMEAVSSSQMTH", "length": 524 }, "evidence": [ { "id": "A0A8V1A5B2", "url": "https://omabrowser.org/oma/group/A0A8V1A5B2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8IZF4-1", "protein_name": "Adhesion G protein-coupled receptor G5", "gene_name": "ADGRG5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDHCGALFLCLCLLTLQNATTETWEELLSYMENMQVSRGRSSVFSSRQLHQLEQMLLNTSFPGYNLTLQTPTIQSLAFKLSCDFSGLSLTSATLKRVPQAGGQHARGQHAMQFPAELTRDACKTRPRELRLICIYFSNTHFFKDENNSSLLNNYVLGAQLSHGHVNNLRDPVNISFWHNQSLEGYTLTCVFWKEGARKQPWGGWSPEGCRTEQPSHSQVLCRCNHLTYFAVLMQLSPALVPAELLAPLTYISLVGCSISIVASLITVLLHFHFRKQSDSLTRIHMNLHASVLLLNIAFLLSPAFAMSPVPGSACTALAAALHYALLSCLTWMAIEGFNLYLLLGRVYNIYIRRYVFKLGVLGWGAPALLVLLSLSVKSSVYGPCTIPVFDSWENGTGFQNMSICWVRSPVVHSVLVMGYGGLTSLFNLVVLAWALWTLRRLRERADAPSVRACHDTVTVLGLTVLLGTTWALAFFSFGVFLLPQLFLFTILNSLYGFFLFLWFCSQRCRSEAEAKAQIEAFSSSQTTQ", "length": 528 }, "evidence": [ { "id": "A0A8V1A5B2", "url": "https://omabrowser.org/oma/group/A0A8V1A5B2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A5B2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5B2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A5B2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5B2" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A5B2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5B2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "cell surface receptor signaling pathway", "id": "GO:0007166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007166", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A5B2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5B2" } ], "pmid": "" }, { "name": "G protein-coupled receptor signaling pathway", "id": "GO:0007186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007186", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A5B2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5B2" } ], "pmid": "" }, { "name": "adenylate cyclase-activating G protein-coupled receptor signaling pathway", "id": "GO:0007189", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007189", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A5B2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5B2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 144, "end_pos": 146, "annotation": "n_glycosylation_sequon" }, { "start_pos": 183, "end_pos": 185, "annotation": "n_glycosylation_sequon" }, { "start_pos": 199, "end_pos": 201, "annotation": "n_glycosylation_sequon" }, { "start_pos": 290, "end_pos": 292, "annotation": "n_glycosylation_sequon" }, { "start_pos": 32, "end_pos": 34, "annotation": "n_glycosylation_sequon" }, { "start_pos": 387, "end_pos": 389, "annotation": "n_glycosylation_sequon" }, { "start_pos": 89, "end_pos": 91, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1A5B2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5B2" }, { "id": "PS50261", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50261" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 2 profile 2", "eco_id": "ECO_0000259", "start_pos": 242, "end_pos": 479, "start_aa": "Leu", "end_aa": "Gly", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1A5B2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5B2" }, { "id": "PS50221", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50221" } ], "ann_type": "Domain_Extent_Annotation", 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"o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A5B4-1", "uniprot_ac": "A0A8V1A5B4", "uniprot_id": "A0A8V1A5B4_CHICK", "mass": { "chemical_mass": 47608.0, "monoisotopic_mass": 47608.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "SRCR domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8V1A5B4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5B4/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A5B4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5B4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5B4", "locus": {} } ], "crossref": [ { "id": "A0A8V1A5B4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A5B4", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR001190", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001190", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036772", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036772", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR19331", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19331", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19331:SF487", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19331:SF487", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00530", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00530", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1A5B4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5B4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A5B4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5B4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MWWPGEFPTPPAPAPLSAAAYTEFQLADGVSVCDGRVEVEARGVWGTLCATAWDLPDLRLVGGRGRCAGRVEVYSEGTWGTICQDSWTRQDATVVCRQLGCGWALEAPGSERFGPEGSEPAWLSWGQSCRHGTGTPRLSLLTGVPTGSEELRLVDGGGRCAGRVEVKHQGKWGSVCSYDFDWDIRGAGVVCRQLGCGTVAHASPYAPFGQECQDPWAGLRLIPDAEALELRLADGGGPCEGRVEVRQGQTWVSVCHGHVDLMAAQVVCRELGCGTALAIPGARHFGAATGLFWNGAFECNGTEPFLSACTQQTPSIQNCTQPTGIICSRKFRLTDGVSACTGRVEVEAQGVWGTLCATAWELPNAQILCDHLGCGSAFSLPPPGHFGMGTGMPRNDALRCSGSERHPGQCPVEVLGQPACPPGHTAAVNCSGGCGSRGDPQQPDIPTQEASS", "length": 452, "header": "tr|A0A8V1A5B4-1|A0A8V1A5B4_CHICK Isoform 1 of SRCR domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1A5B4-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A5B4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5B4/entry#A0A8V1A5B4-1", "sequence": { "sequence": "MWWPGEFPTPPAPAPLSAAAYTEFQLADGVSVCDGRVEVEARGVWGTLCATAWDLPDLRLVGGRGRCAGRVEVYSEGTWGTICQDSWTRQDATVVCRQLGCGWALEAPGSERFGPEGSEPAWLSWGQSCRHGTGTPRLSLLTGVPTGSEELRLVDGGGRCAGRVEVKHQGKWGSVCSYDFDWDIRGAGVVCRQLGCGTVAHASPYAPFGQECQDPWAGLRLIPDAEALELRLADGGGPCEGRVEVRQGQTWVSVCHGHVDLMAAQVVCRELGCGTALAIPGARHFGAATGLFWNGAFECNGTEPFLSACTQQTPSIQNCTQPTGIICSRKFRLTDGVSACTGRVEVEAQGVWGTLCATAWELPNAQILCDHLGCGSAFSLPPPGHFGMGTGMPRNDALRCSGSERHPGQCPVEVLGQPACPPGHTAAVNCSGGCGSRGDPQQPDIPTQEASS", "length": 452, "header": "tr|A0A8V1A5B4-1|A0A8V1A5B4_CHICK Isoform 1 of SRCR domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1A5B4-1" }, "locus": { "chromosome": "5", "start_pos": 16453289, "end_pos": 16446512, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063556.1", "url": "https://www.ensembl.org/id/ENSGALT00010063556.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039232.1", "url": "https://www.ensembl.org/id/ENSGALP00010039232.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 9, "start_aa": "Thr", "end_pos": 9, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr9", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "detection of bacterial lipoprotein", "id": "GO:0042494", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042494", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A5B4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5B4" } ], "pmid": "" }, { "name": "defense response", "id": "GO:0006952", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006952", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A5B4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5B4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "scavenger receptor activity", "id": "GO:0005044", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005044", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A5B4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5B4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A5B4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5B4" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A5B4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5B4" } ], "pmid": "" }, { "name": "extracellular matrix", "id": "GO:0031012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031012", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A5B4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5B4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 300, "end_pos": 302, "annotation": "n_glycosylation_sequon" }, { "start_pos": 318, "end_pos": 320, "annotation": "n_glycosylation_sequon" }, { "start_pos": 429, "end_pos": 431, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1A5B4", "database": "UniProtKB", "url": 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"site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A5D4-1", "uniprot_ac": "A0A8V1A5D4", "uniprot_id": "A0A8V1A5D4_CHICK", "mass": { "chemical_mass": 67865.0, "monoisotopic_mass": 67865.0 }, "refseq": {}, "gene_names": [ { "name": "BTN1A1", "type": "recommended", "evidence": [ { "id": "A0A8V1A5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5D4" } ] } ], "protein_names": [ { "name": "Butyrophilin subfamily 1 member A1", "type": "synonym", "evidence": [ { "id": "A0A8V1A5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5D4/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A5D4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5D4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "BTN1A1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5D4", "locus": { "chromosome": "28", "start_pos": 1216361, "end_pos": 1222907, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027725", "url": "https://www.ensembl.org/id/ENSGALG00010027725" } ] } } ], "crossref": [ { "id": "A0A8V1A5D4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A5D4", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd05713", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05713", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12888", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12888", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001870", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001870", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003877", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003877", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003879", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003879", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006574", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006574", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013106", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013106", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043136", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043136", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR053896", "url": "https://www.ebi.ac.uk/interpro/entry/IPR053896", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A5D0", "url": "https://www.orthodb.org/?gene=A0A8V1A5D0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A5D4", "url": "https://www.orthodb.org/?gene=A0A8V1A5D4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AA94", "url": "https://www.orthodb.org/?gene=A0A8V1AA94", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AD15", "url": "https://www.orthodb.org/?gene=A0A8V1AD15", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24100", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24100", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24100:SF149", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24100:SF149", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00622", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00622", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07686", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07686", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13765", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13765", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22705", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22705", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-8851680", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8851680", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1A5D0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5D0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A5D0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5D0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A5D4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5D4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A5D4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5D4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AA94", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA94", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AA94-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA94-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AD15", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD15", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AD15-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD15-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLEKSQHPSTVSTHCRLTVGKKGSDGSEHLQFALRSPDLIRSWLEKSVPTVSPCCLQRYTVGAPAPPLPLANCRRVIRALCAVQSCEPRWVPAHAQQLHFLLPALHPSLAEPGLHWWVGSMKTMFFGCCLRCSLLAAVIYSSVFRIHELQSVPFSVQGPPDPVAVAVGQDVVLPCHLSPEQSVQHMEVMWFRDQFTPFVHRYRDGQDHYGDQELRYQGCTEMLKDSLANGSVNLRIFRVQLSDRGRYTCLVRSDLGYDEAVVELKVTASGSAPLIALQRYQDGGIRVACRSAGWFPQPQLLWRDPHGQWLPSLSENITQDGGGLYTAESVLILAGGVSQELACVVRAALHNQEKESAFSIADPFFQNARPWKIALSVILVAVVALSIVAVYLLKMKGKYEKKIAAQAAELGDRDTKIEKQAEELVWIRYAVPIEDAEVVLDPDTAHCDLVLTDDGKSVKRTDRRQDVPSRPERFDPWRCVLGCKGFTAGRHCWEVEVVLDGGGWTVGVSREDVRRKGEIEFGPEEGIWAVGQWAGQFQALTSPQRTLLPDVCTPTRVRVALDYEVGRVAFYSVDEEIPIFTFPPVSFQGIKVHPWLWLGPGTQLKMWP", "length": 608, "header": "tr|A0A8V1A5D4-1|A0A8V1A5D4_CHICK Isoform 1 of Butyrophilin subfamily 1 member A1 OS=Gallus gallus OX=9031 GN=BTN1A1 PE=3 SV=1 CANONICAL=A0A8V1A5D4-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A5D0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5D4/entry#A0A8V1A5D0-1", "sequence": { "sequence": "MGQQLHFLLPALHPSLAEPGLHWWVGSMKTMFFGCCLRCSLLAAVIYSSVFRIHELQSVPFSVQGPPDPVAVAVGQDVVLPCHLSPEQSVQHMEVMWFRDQFTPFVHRYRDGQDHYGDQELRYQGCTEMLKDSLANGSVNLRIFRVQLSDRGRYTCLVRSDLGYDEAVVELKVTASGSAPLIALQRYQDGGIRVACRSAGWFPQPQLLWRDPHGQWLPSLSENITQDGGGLYTAESVLILAGGVSQELACVVRAALHNQEKESAFSIADPFFQNARPWKIALSVILVAVVALSIVAVYLLKMKGKYEKKIAAQAAELGDRDTKIEKQAEELVWIRYAVPIEDAEVVLDPDTAHCDLVLTDDGKSVKRTDRRQDVPSRPERFDPWRCVLGCKGFTAGRHCWEVEVVLDGGGWTVGVSREDVRRKGEIEFGPEEGIWAVGQWAGQFQALTSPQRTLLPDVCTPTRVRVALDYEVGRVAFYSVDEEIPIFTFPPVSFQGIKVHPWLWLGPGTQLKMWP", "length": 515, "header": "tr|A0A8V1A5D0-1|A0A8V1A5D4_CHICK Computationally mapped isoform of Butyrophilin subfamily 1 member A1 OS=Gallus gallus OX=9031 GN=BTN1A1 PE=3 SV=1 CANONICAL=A0A8V1A5D4-1" }, "locus": { "chromosome": "28", "start_pos": 1221994, "end_pos": 1216699, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067210.1", "url": "https://www.ensembl.org/id/ENSGALT00010067210.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041114.1", "url": "https://www.ensembl.org/id/ENSGALP00010041114.1" } ] } }, { "isoform_ac": "A0A8V1A5D4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5D4/entry#A0A8V1A5D4-1", "sequence": { "sequence": "MLEKSQHPSTVSTHCRLTVGKKGSDGSEHLQFALRSPDLIRSWLEKSVPTVSPCCLQRYTVGAPAPPLPLANCRRVIRALCAVQSCEPRWVPAHAQQLHFLLPALHPSLAEPGLHWWVGSMKTMFFGCCLRCSLLAAVIYSSVFRIHELQSVPFSVQGPPDPVAVAVGQDVVLPCHLSPEQSVQHMEVMWFRDQFTPFVHRYRDGQDHYGDQELRYQGCTEMLKDSLANGSVNLRIFRVQLSDRGRYTCLVRSDLGYDEAVVELKVTASGSAPLIALQRYQDGGIRVACRSAGWFPQPQLLWRDPHGQWLPSLSENITQDGGGLYTAESVLILAGGVSQELACVVRAALHNQEKESAFSIADPFFQNARPWKIALSVILVAVVALSIVAVYLLKMKGKYEKKIAAQAAELGDRDTKIEKQAEELVWIRYAVPIEDAEVVLDPDTAHCDLVLTDDGKSVKRTDRRQDVPSRPERFDPWRCVLGCKGFTAGRHCWEVEVVLDGGGWTVGVSREDVRRKGEIEFGPEEGIWAVGQWAGQFQALTSPQRTLLPDVCTPTRVRVALDYEVGRVAFYSVDEEIPIFTFPPVSFQGIKVHPWLWLGPGTQLKMWP", "length": 608, "header": "tr|A0A8V1A5D4-1|A0A8V1A5D4_CHICK Isoform 1 of Butyrophilin subfamily 1 member A1 OS=Gallus gallus OX=9031 GN=BTN1A1 PE=3 SV=1 CANONICAL=A0A8V1A5D4-1" }, "locus": { "chromosome": "28", "start_pos": 1222708, "end_pos": 1216699, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067215.1", "url": "https://www.ensembl.org/id/ENSGALT00010067215.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041119.1", "url": "https://www.ensembl.org/id/ENSGALP00010041119.1" } ] } }, { "isoform_ac": "A0A8V1AA94-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5D4/entry#A0A8V1AA94-1", "sequence": { "sequence": "MKTMFFGCCLRCSLLAAVIYSSVFRIHELQSVPFSVQGPPDPVAVAVGQDVVLPCHLSPEQSVQHMEVMWFRDQFTPFVHRYRDGQDHYGDQELRYQGCTEMLKDSLANGSVNLRIFRVQLSDRGRYTCLVRSDLGYDEAVVELKVTASGSAPLIALQRYQDGGIRVACRSAGWFPQPQLLWRDPHGQWLPSLSENITQDGGGLYTAESVLILAGGVSQELACVVRAALHNQEKESAFSIADPFFQNARPWKIALSVILVAVVALSIVAVYLLKMKGTVLGWVWIRYAVPIEDAEVVLDPDTAHCDLVLTDDGKSVKRTDRRQDVPSRPERFDPWRCVLGCKGFTAGRHCWEVEVVLDGGGWTVGVSREDVRRKGEIEFGPEEGIWAVGQWAGQFQALTSPQRTLLPDVCTPTRVRVALDYEVGRVAFYSVDEEIPIFTFPPVSFQGIKVHPWLWLGPGTQLKMWP", "length": 466, "header": "tr|A0A8V1AA94-1|A0A8V1AA94_CHICK Computationally mapped isoform of Butyrophilin subfamily 1 member A1 OS=Gallus gallus OX=9031 GN=BTN1A1 PE=3 SV=1 CANONICAL=A0A8V1A5D4-1" }, "locus": { "chromosome": "28", "start_pos": 1221310, "end_pos": 1216699, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067212.1", "url": "https://www.ensembl.org/id/ENSGALT00010067212.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041116.1", "url": "https://www.ensembl.org/id/ENSGALP00010041116.1" } ] } }, { "isoform_ac": "A0A8V1AD15-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5D4/entry#A0A8V1AD15-1", "sequence": { "sequence": "MGQQLHFLLPALHPSLAEPGLHWWVGSMKTMFFGCCLRCSLLAAVIYSSVFRIHELQSVPFSVQGPPDPVAVAVGQDVVLPCHLSPEQSVQHMEVMWFRDQFTPFVHRYRDGQDHYGDQELRYQGCTEMLKDSLANGSVNLRIFRVQLSDRGRYTCLVRSDLGYDEAVVELKVTASGSAPLIALQRYQDGGIRVACRSAGWFPQPQLLWRDPHGQWLPSLSENITQDGGGLYTAESVLILAGGVSQELACVVRAALHNQEKESAFSIADPFFQNARPWKIALSVILVAVVALSIVAVYLLKMKGKYEKKIAAQAAELGDRDTKIEKQAEELAEVVLDPDTAHCDLVLTDDGKSVKRTDRRQDVPSRPERFDPWRCVLGCKGFTAGRHCWEVEVVLDGGGWTVGVSREDVRRKGEIEFGPEEGIWAVGQWAGQFQALTSPQRTLLPDVCTPTRVRVALDYEVGRVAFYSVDEEIPIFTFPPVSFQGIKVHPWLWLGPGTQLKMWP", "length": 504, "header": "tr|A0A8V1AD15-1|A0A8V1AD15_CHICK Computationally mapped isoform of Butyrophilin subfamily 1 member A1 OS=Gallus gallus OX=9031 GN=BTN1A1 PE=3 SV=1 CANONICAL=A0A8V1A5D4-1" }, "locus": { "chromosome": "28", "start_pos": 1221994, "end_pos": 1216699, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067214.1", "url": "https://www.ensembl.org/id/ENSGALT00010067214.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041118.1", "url": "https://www.ensembl.org/id/ENSGALP00010041118.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-8851680", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8851680", "resource": "Reactome", "description": "Butyrophilin (BTN) family interactions" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A5D4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5D4" } ], "pmid": "" }, { "name": "external side of plasma membrane", "id": "GO:0009897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009897", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A5D4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5D4" } ], "pmid": "" } ] }, { "name": "Biological Process", 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"table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A5G6-1", "uniprot_ac": "A0A8V1A5G6", "uniprot_id": "A0A8V1A5G6_CHICK", "mass": { "chemical_mass": 73289.0, "monoisotopic_mass": 73289.0 }, "refseq": { "ac": "NP_001338411", "name": "epidermal differentiation protein containing DPCC motifs", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001338411" }, "gene_names": [ { "name": "LOC101751279", "type": "recommended", "evidence": [ { "id": "A0A8V1A5G6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5G6" } ] }, { "name": "EDDM", "type": "synonym", "evidence": [ { "id": "NP_001338411", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001338411" } ] }, { "name": "LOC101751279", "type": "synonym", "evidence": [ { "id": "NP_001338411", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001338411" } ] } ], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "A0A8V1A5G6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5G6/entry#names_and_taxonomy" } ] }, { "name": "epidermal differentiation protein containing DPCC motifs", "type": "synonym", "evidence": [ { "id": "NP_001338411", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001338411" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMN02738215, SAMN02738216 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000349.1. On Oct 28, 2021 this sequence version replaced NP_001338411.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001338411", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001338411" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A5G6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5G6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC101751279", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5G6", "locus": {} } ], "crossref": [ { "id": "101751279", "url": "https://www.ncbi.nlm.nih.gov/gene/101751279", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "gga:101751279", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:101751279", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GSACTCE", "url": "https://omabrowser.org/oma/group/GSACTCE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A5G0", "url": "https://www.orthodb.org/?gene=A0A8V1A5G0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A5G6", "url": "https://www.orthodb.org/?gene=A0A8V1A5G6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AAB9", "url": "https://www.orthodb.org/?gene=A0A8V1AAB9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AFR0", "url": "https://www.orthodb.org/?gene=A0A8V1AFR0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AHM2", "url": "https://www.orthodb.org/?gene=A0A8V1AHM2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "NP_001338411", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001338411", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1A5G0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5G0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A5G0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5G0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A5G6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5G6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A5G6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5G6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AAB9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAB9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AAB9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAB9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFR0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFR0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFR0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFR0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHM2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHM2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHM2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHM2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLCQTDCQRGLPCLPPHVVLVRNLPVSRSVDPCNSVCSVSRLNTCADPCYYARVPQGTTTYLKLGSCDLRQIALDPCCLGITTLTDPCCQDVTRCSSTRCVDPCCCKVTECSSTRYVDSCCQDATQCTTRCMDSCCQDATQCTTRCVDPCCQDATQCTTRCVDPCRQDATQCTTRCVDPCCQDVTKCTTRCVDPCRQDTTQCTTRCVDPCCQDVTRCTTRCVDPCCKEVTRCTTRCVDPCCQDVTRCTTRCVDPCCKEVTRCTTRCVDPCCQDVTKCTTRCVDPCCKEVTKCTTTRCVDPCCKEVTRCTTRCADPCCGEVTKCTTKYVDPCCRPVTRCATTCVDPCCGRVTKCTNKCVDPCYGAVTRCSTKCVEPCCEEVSKCTSRCVDPCCREVTKCTTRCVDPCCGRVTKCARYKNPCCGEVSKCTTKCVDPCCGRVTKYVDPCCREVTSCKTRCVDPCCKEVTRCTTTCVDPCCAEVTKCATKCIDPCCQDATKCTTTCVDPCCREVTKCTTTCVDPCCQEVTKCTTTCVDPCCKEVTKCTTTCVDPCCKEVTKCTTTCVDPCCQEVTKCTTTCVDPCCREVAKCTTTCVDPCCQDATQCTTRCADPCCQDATQCTTTCVDPCCQDVTQCTSTCVDPCVPPCFVRPTPLCASICGRHYSISCADICCRK", "length": 672, "header": "tr|A0A8V1A5G6-1|A0A8V1A5G6_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN=LOC101751279 PE=4 SV=1 CANONICAL=A0A8V1A5G6-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A5G0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5G6/entry#A0A8V1A5G0-1", "sequence": { "sequence": "MLCQTDCQRGLPCLPPHVVLVRNLPVSRSVDPCNSVCSVSRLNTCADPCYYARVPQGTTTYLKLGSCDLRQIALDPCCLGITTLTDPCCQDVTRCSSTRCVDPCCCKVTECSSTRYVDSCCQDATQCTTRCMDSCCQDATQCTTRCVDPCCQDATQCTTRCVDPCRQDATQCTTRCVDPCCQDVTKCTTRCVDPCRQDTTQCTTRCVDPCCQDVTRCTTRCVDPCCKEVTRCTTRCVDPCCQDVTRCTTRCVDPCCKEVTRCTTRCVDPCCQDVTKCTTRCVDPCCKEVTKCTTTRCVDPCCKEVTRCTTRCADPCCGEVTKCTTKYVDPCCRPVTRCATTCVDPCCGRVTKCTNKCVDPCYGAVTRCSTKCVEPCCEEVSKCTSRCVDPCCREVTKCTTRCVDPCCGRVTKCARYKNPCCGEVSKCTTKCVDPCCGRVTKYVDPCCREVTSCKTRCVDPCCKEVTRCTTTCVDPCCAEVTKCATKCIDPCCQDATKCTTTCVDPCCREVTKCTTTCVDPCCQEVTKCTTTCVDPCCKEVTKCTTTCVDPCCREVAKCTTTCVDPCCQDATQCTTRCADPCCQDATQCTTTCVDPCCQDVTQCTSTCVDPCVPPCFVRPTPLCASICGRHYSISCADICCRK", "length": 642, "header": "tr|A0A8V1A5G0-1|A0A8V1A5G6_CHICK Computationally mapped isoform of Uncharacterized protein OS=Gallus gallus OX=9031 GN=LOC101751279 PE=4 SV=1 CANONICAL=A0A8V1A5G6-1" }, "locus": { "chromosome": "25", "start_pos": 1310524, "end_pos": 1308509, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067240.1", "url": "https://www.ensembl.org/id/ENSGALT00010067240.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041144.1", "url": "https://www.ensembl.org/id/ENSGALP00010041144.1" } ] } }, { "isoform_ac": "A0A8V1A5G6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5G6/entry#A0A8V1A5G6-1", "sequence": { "sequence": "MLCQTDCQRGLPCLPPHVVLVRNLPVSRSVDPCNSVCSVSRLNTCADPCYYARVPQGTTTYLKLGSCDLRQIALDPCCLGITTLTDPCCQDVTRCSSTRCVDPCCCKVTECSSTRYVDSCCQDATQCTTRCMDSCCQDATQCTTRCVDPCCQDATQCTTRCVDPCRQDATQCTTRCVDPCCQDVTKCTTRCVDPCRQDTTQCTTRCVDPCCQDVTRCTTRCVDPCCKEVTRCTTRCVDPCCQDVTRCTTRCVDPCCKEVTRCTTRCVDPCCQDVTKCTTRCVDPCCKEVTKCTTTRCVDPCCKEVTRCTTRCADPCCGEVTKCTTKYVDPCCRPVTRCATTCVDPCCGRVTKCTNKCVDPCYGAVTRCSTKCVEPCCEEVSKCTSRCVDPCCREVTKCTTRCVDPCCGRVTKCARYKNPCCGEVSKCTTKCVDPCCGRVTKYVDPCCREVTSCKTRCVDPCCKEVTRCTTTCVDPCCAEVTKCATKCIDPCCQDATKCTTTCVDPCCREVTKCTTTCVDPCCQEVTKCTTTCVDPCCKEVTKCTTTCVDPCCKEVTKCTTTCVDPCCQEVTKCTTTCVDPCCREVAKCTTTCVDPCCQDATQCTTRCADPCCQDATQCTTTCVDPCCQDVTQCTSTCVDPCVPPCFVRPTPLCASICGRHYSISCADICCRK", "length": 672, "header": "tr|A0A8V1A5G6-1|A0A8V1A5G6_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN=LOC101751279 PE=4 SV=1 CANONICAL=A0A8V1A5G6-1" }, "locus": { "chromosome": "25", "start_pos": 1310524, "end_pos": 1308509, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067242.1", "url": "https://www.ensembl.org/id/ENSGALT00010067242.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041146.1", "url": "https://www.ensembl.org/id/ENSGALP00010041146.1" } ] } }, { "isoform_ac": "A0A8V1AAB9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5G6/entry#A0A8V1AAB9-1", "sequence": { "sequence": "CTTTRCVDPCCKEVTRCTTRCADPCCGEVTKCTTKYVDPCCRPVTRCATTCVDPCCGRVTKCTNKCVDPCYGAVTRCSTKCVEPCCEEVSKCTSRCVDPCCREVTKCTTRCVDPCCGRVTKCARYKNPCCGEVSKCTTKCVDPCCKEVTRCTTTCVDPCCAEVTKCATKCIDPCCQDATKCTTTCVDPCCREVTKCTTTCVDPCCQEVTKCTTTCVDPCCKEVTKCTTTCVDPCCKEVTKCTTTCVDPCCQEVTKCTTTCVDPCCREVAKCTTTCVDPCCQDATQCTTRCADPCCQDATQCTTTCVDPCCQDVTQCTSTCVDPCVPPCFVRPTPLCASICGRHYSISCADICCRK", "length": 355, "header": "tr|A0A8V1AAB9-1|A0A8V1AAB9_CHICK Computationally mapped isoform of MAGB4 protein OS=Gallus gallus OX=9031 GN=LOC101751279 PE=4 SV=1 CANONICAL=A0A8V1A5G6-1" }, "locus": { "chromosome": "25", "start_pos": 1310524, "end_pos": 1309382, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067237.1", "url": "https://www.ensembl.org/id/ENSGALT00010067237.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041141.1", "url": "https://www.ensembl.org/id/ENSGALP00010041141.1" } ] } }, { "isoform_ac": "A0A8V1AFR0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5G6/entry#A0A8V1AFR0-1", "sequence": { "sequence": "MLCQTDCQRGLPCLPPHVVLVRNLPVSRSVDPCNSVCSVSRLNTCADPCYYARVPQGTTTYLKLGSCDLRQIALDPCCLGITTLTDPCCQDVTRCSSTRCVDPCCCKVTECSSTRYVDSCCQDATQCTTRCMDSCCQDATQCTTRCVDPCCQDATQCTTRCVDPCRQDATQCTTRCVDPCCQDVTKCTTRCVDPCRQDTTQCTTRCVDPCCQDVTRCTTRCVDPCCKEVTRCTTRCVDPCCQDVTKCTTRCVDPCCKEVTKCTTTRCVDPCCKEVTRCTTRCADPCCGEVTKCTTKYVDPCCRPVTRCATTCVDPCCGRVTKCTNKCVDPCYGAVTRCSTKCVEPCCEEVSKCTSRCVDPCCREVTKCTTRCVDPCCGRVTKCARYKNPCCGEVSKCTTKCVDPCCGRVTKYVDPCCREVTSCKTRCVDPCCKEVTRCTTTCVDPCCAEVTKCATKCIDPCCQDATKCTTTCVDPCCREVTKCTTTCVDPCCQEVTKCTTTCVDPCCKEVTKCTTTCVDPCCKEVTKCTTTCVDPCCQEVTKCTTTCVDPCCREVAKCTTTCVDPCCQDATQCTTRCADPCCQDATQCTTTCVDPCCQDVTQCTSTCVDPCVPPCFVRPTPLCASICGRHYSISCADICCRK", "length": 642, "header": "tr|A0A8V1AFR0-1|A0A8V1AFR0_CHICK Computationally mapped isoform of Uncharacterized protein OS=Gallus gallus OX=9031 GN=LOC101751279 PE=4 SV=1 CANONICAL=A0A8V1A5G6-1" }, "locus": { "chromosome": "25", "start_pos": 1310524, "end_pos": 1308509, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067243.1", "url": "https://www.ensembl.org/id/ENSGALT00010067243.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041147.1", "url": "https://www.ensembl.org/id/ENSGALP00010041147.1" } ] } }, { "isoform_ac": "A0A8V1AHM2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5G6/entry#A0A8V1AHM2-1", "sequence": { "sequence": "MLCQTDCQRGLPCLPPHVVLVRNLPVSRSVDPCNSVCSVSRLNTCADPCYYARVPQGTTTYLKLGSCDLRQIALDPCCLGITTLTDPCCQDVTRCSSTRCVDPCCCKVTECSSTRYVDSCCQDATQCTTRCVDPCCQDATQCTTRCVDPCRQDATQCTTRCVDPCCQDVTKCTTRCVDPCRQDTTQCTTRCVDPCCQDVTRCTTRCVDPCCKEVTRCTTRCVDPCCKEVTRCTTRCVDPCCQDVTKCTTRCVDPCCKEVTKCTTTRCVDPCCKEVTRCTTRCADPCCGEVTKCTTKYVDPCCRPVTRCATTCVDPCCGRVTKCTNKCVDPCYGAVTRCSTKCVEPCCEEVSKCTSRCVDPCCREVTKCTTRCVDPCCGRVTKCARYKNPCCGEVSKCTTKCVDPCCGRVTKYVDPCCREVTSCKTRCVDPCCKEVTRCTTTCVDPCCAEVTKCATKCIDPCCQDATKCTTTCVDPCCREVTKCTTTCVDPCCQEVTKCTTTCVDPCCKEVTKCTTTCVDPCCKEVTKCTTTCVDPCCQEVTKCTTTCVDPCCREVAKCTTTCVDPCCQDATQCTTRCADPCCQDATQCTTTCVDPCCQDVTQCTSTCVDPCVPPCFVRPTPLCASICGRHYSISCADICCRK", "length": 642, "header": "tr|A0A8V1AHM2-1|A0A8V1A5G6_CHICK Computationally mapped isoform of Uncharacterized protein OS=Gallus gallus OX=9031 GN=LOC101751279 PE=4 SV=1 CANONICAL=A0A8V1A5G6-1" }, "locus": { "chromosome": "25", "start_pos": 1310524, "end_pos": 1308509, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067241.1", "url": "https://www.ensembl.org/id/ENSGALT00010067241.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041145.1", "url": "https://www.ensembl.org/id/ENSGALP00010041145.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:101751279", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:101751279", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A5J2-1", "uniprot_ac": "A0A8V1A5J2", "uniprot_id": "A0A8V1A5J2_CHICK", "mass": { "chemical_mass": 62636.0, "monoisotopic_mass": 62636.0 }, "refseq": {}, "gene_names": [ { "name": "MAB21L4", "type": "recommended", "evidence": [ { "id": "A0A8V1A5J2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5J2" } ] } ], "protein_names": [ { "name": "Mab-21 like 4", "type": "synonym", "evidence": [ { "id": "A0A8V1A5J2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5J2/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A5J2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5J2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MAB21L4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5J2", "locus": { "chromosome": "9", "start_pos": 4535692, "end_pos": 4540188, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010024962", "url": "https://www.ensembl.org/id/ENSGALG00010024962" } ] } } ], "crossref": [ { "id": "A0A8V1A5J2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A5J2", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR024810", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024810", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046906", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046906", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A5J2", "url": "https://www.orthodb.org/?gene=A0A8V1A5J2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10656", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10656", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10656:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10656:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF20266", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20266", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1A5J2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5J2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A5J2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5J2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVGLEGTSQPTQFQLPAVGCVPPTGSGSQGPMQPSPEHLQGWGSPTSVGSSVRAEVPSHQSRVRAMVISRSTRPSALQRGRGDDGAAPSPAAALPLARPGSRPGATPQPGFPPPSARSLPALPPTERSARSRAAPAMAAGGCRWRSCLEVVASRQGQRVQHFQQAEDILLTLLEHVHAEEPRFLVDYSRNLEAFEFVLCASEDAVVVEVPLRIDGDALRVRPCQPTDNGSTGHGQPGACSLEVPSVVTGVGDWTSTGSTGGMEQVRCLAPGKVLQRLKELLVSAIVQCQRRSLLQPGDLRAENLVEDAMELPLLVRGGWRTIRFDVVPVVRRRQESPGPDGRQRDRGFPEGTLQKATGDAHFVPASNHCWRPSTHLPILKLLWAVDSLQGPRLDSLRLLEQLRSQDWREEDGRDGLTFNHLKMVLLWSTELFPSPEDWQDLEGSVYRLLVVLLRCLATQRLPHFLHPEQNLFQGDPHRLASLYPKVEAFAWDPARFLRFHFGLPARADGVQADPALRALLHLPAKDGTYWDTAYFDVLLSQVYQIQDATRRSAMSWLLTKLRRDIPLQS", "length": 569, "header": "tr|A0A8V1A5J2-1|A0A8V1A5J2_CHICK Isoform 1 of Mab-21 like 4 OS=Gallus gallus OX=9031 GN=MAB21L4 PE=4 SV=1 CANONICAL=A0A8V1A5J2-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A5J2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5J2/entry#A0A8V1A5J2-1", "sequence": { "sequence": "MVGLEGTSQPTQFQLPAVGCVPPTGSGSQGPMQPSPEHLQGWGSPTSVGSSVRAEVPSHQSRVRAMVISRSTRPSALQRGRGDDGAAPSPAAALPLARPGSRPGATPQPGFPPPSARSLPALPPTERSARSRAAPAMAAGGCRWRSCLEVVASRQGQRVQHFQQAEDILLTLLEHVHAEEPRFLVDYSRNLEAFEFVLCASEDAVVVEVPLRIDGDALRVRPCQPTDNGSTGHGQPGACSLEVPSVVTGVGDWTSTGSTGGMEQVRCLAPGKVLQRLKELLVSAIVQCQRRSLLQPGDLRAENLVEDAMELPLLVRGGWRTIRFDVVPVVRRRQESPGPDGRQRDRGFPEGTLQKATGDAHFVPASNHCWRPSTHLPILKLLWAVDSLQGPRLDSLRLLEQLRSQDWREEDGRDGLTFNHLKMVLLWSTELFPSPEDWQDLEGSVYRLLVVLLRCLATQRLPHFLHPEQNLFQGDPHRLASLYPKVEAFAWDPARFLRFHFGLPARADGVQADPALRALLHLPAKDGTYWDTAYFDVLLSQVYQIQDATRRSAMSWLLTKLRRDIPLQS", "length": 569, "header": "tr|A0A8V1A5J2-1|A0A8V1A5J2_CHICK Isoform 1 of Mab-21 like 4 OS=Gallus gallus OX=9031 GN=MAB21L4 PE=4 SV=1 CANONICAL=A0A8V1A5J2-1" }, "locus": { "chromosome": "9", "start_pos": 4539959, "end_pos": 4536456, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010060959.1", "url": "https://www.ensembl.org/id/ENSGALT00010060959.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010037708.1", "url": "https://www.ensembl.org/id/ENSGALP00010037708.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 228, "end_pos": 230, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1A5J2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5J2" }, { "id": "PF20266", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20266" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Mab-21-like HhH/H2TH-like", "eco_id": "ECO_0000259", "start_pos": 394, "end_pos": 474, "start_aa": "Asp", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 228, "end_pos": 230 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A5J3-1", "uniprot_ac": "A0A8V1A5J3", "uniprot_id": "A0A8V1A5J3_CHICK", "mass": { "chemical_mass": 109478.0, "monoisotopic_mass": 109478.0 }, "refseq": {}, "gene_names": [ { "name": "R3HDM2", "type": "recommended", "evidence": [ { "id": "A0A8V1A5J3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5J3" } ] } ], "protein_names": [ { "name": "R3H domain containing 2", "type": "synonym", "evidence": [ { "id": "A0A8V1A5J3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5J3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A5J3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5J3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "R3HDM2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5J3", "locus": { "chromosome": "34", "start_pos": 1698417, "end_pos": 1729238, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010025506", "url": "https://www.ensembl.org/id/ENSGALG00010025506" } ] } } ], "crossref": [ { "id": "A0A8V1A5J3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A5J3", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd02642", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02642", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001374", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001374", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024771", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024771", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036867", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036867", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051937", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051937", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A5J3", "url": "https://www.orthodb.org/?gene=A0A8V1A5J3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A834", "url": "https://www.orthodb.org/?gene=A0A8V1A834", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AAN7", "url": "https://www.orthodb.org/?gene=A0A8V1AAN7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15672", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15672", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15672:SF13", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15672:SF13", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01424", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01424", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12752", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12752", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1A5J3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5J3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A5J3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5J3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A834", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A834", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A834-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A834-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AAN7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAN7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AAN7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAN7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MIPCSLFRKAPWWTALLRCCWETALTSWEQFPAPGCPPLRRRALKMSNSNTAQESLEIMKETEKKVVEESVSKTKYVSRSPSKEEAEKDGGEEVSVRQEAQRRTSGHGHARKRAKSNSKLKLVRSLAVCEESSSPFVDGLLESQDIIQLHVSCPSDKEEEKSTKDGAEKEEKEKNKDKAPRKMLSRDSSQEYTDSTGIDLHEFLVNTLKKNPRDRMMLLKLEQEILEFISDSNNQFKKFPQMTSYHRMLLHRVAAYFGMDHNVDQTGKAVIINKTSNTRIPEQRFSEHIKDEKNAEFPQRFILKRDDTSMDRDDNQIRLPLQDGRRSKSIEEREEEYQRARERIFARETGQNGYLTDSRANRDGLSRASGSRQSSTESEIKSLEPRPWSSTDSDGSIRSLRPPVTKASSFSGISILTRGDSIGSSKGSTASRASRAGLALGAPEACSQPPSSQPSRGLLPCASQQPQPPPPQQPQPQGLPPTAQQQPAMSNHMMSQADELSNPFGQISLSRQGSTEAPDPSSAMFQSSLISQHPQQAGFIMATPGQPIPTSNYSASGHTVPTQQVLQPQGYIQPPQQIQVSYYPPGQYPNSSQQYRSLSHPVAYSSQRTQQLPQQAQQPGLQPMMSNQQQTYQGVMGVQQAQSPGLLNSQRNSMGGQMQSVLGVQQTQPPSLLSSQRSGMGSQMQGLMVQYTPLPSYQVPVANESQSVVQQPFQQPVLVPASQSVQGGLQTGGVPIYYSVIPTAQQNGTSPSVGFLQPPGSEQYQLPQSPSPCSPSQMQQQYSGVSPSGPGVVVMQLNVPNGPQPPQNAPVVQWSHCKYYSLEQRGQKPGDLYNPDSSGQASTQLSSPITSPTQSPTPSPVTNLNSVCTGLSPLPVLTQFPRPMGAAQGDGRYSLLGQPLQYNLSICPPPAAPQPAQLQRTPGAERAEARQPQQEADPQVSIHRPGDERCSAGPGAGGDGPPGGHHADGGGQTLHSALHGRRQNPMAQRDSGAARGRRRLR", "length": 1001, "header": "tr|A0A8V1A5J3-1|A0A8V1A5J3_CHICK Isoform 1 of R3H domain containing 2 OS=Gallus gallus OX=9031 GN=R3HDM2 PE=4 SV=1 CANONICAL=A0A8V1A5J3-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A5J3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5J3/entry#A0A8V1A5J3-1", "sequence": { "sequence": "MIPCSLFRKAPWWTALLRCCWETALTSWEQFPAPGCPPLRRRALKMSNSNTAQESLEIMKETEKKVVEESVSKTKYVSRSPSKEEAEKDGGEEVSVRQEAQRRTSGHGHARKRAKSNSKLKLVRSLAVCEESSSPFVDGLLESQDIIQLHVSCPSDKEEEKSTKDGAEKEEKEKNKDKAPRKMLSRDSSQEYTDSTGIDLHEFLVNTLKKNPRDRMMLLKLEQEILEFISDSNNQFKKFPQMTSYHRMLLHRVAAYFGMDHNVDQTGKAVIINKTSNTRIPEQRFSEHIKDEKNAEFPQRFILKRDDTSMDRDDNQIRLPLQDGRRSKSIEEREEEYQRARERIFARETGQNGYLTDSRANRDGLSRASGSRQSSTESEIKSLEPRPWSSTDSDGSIRSLRPPVTKASSFSGISILTRGDSIGSSKGSTASRASRAGLALGAPEACSQPPSSQPSRGLLPCASQQPQPPPPQQPQPQGLPPTAQQQPAMSNHMMSQADELSNPFGQISLSRQGSTEAPDPSSAMFQSSLISQHPQQAGFIMATPGQPIPTSNYSASGHTVPTQQVLQPQGYIQPPQQIQVSYYPPGQYPNSSQQYRSLSHPVAYSSQRTQQLPQQAQQPGLQPMMSNQQQTYQGVMGVQQAQSPGLLNSQRNSMGGQMQSVLGVQQTQPPSLLSSQRSGMGSQMQGLMVQYTPLPSYQVPVANESQSVVQQPFQQPVLVPASQSVQGGLQTGGVPIYYSVIPTAQQNGTSPSVGFLQPPGSEQYQLPQSPSPCSPSQMQQQYSGVSPSGPGVVVMQLNVPNGPQPPQNAPVVQWSHCKYYSLEQRGQKPGDLYNPDSSGQASTQLSSPITSPTQSPTPSPVTNLNSVCTGLSPLPVLTQFPRPMGAAQGDGRYSLLGQPLQYNLSICPPPAAPQPAQLQRTPGAERAEARQPQQEADPQVSIHRPGDERCSAGPGAGGDGPPGGHHADGGGQTLHSALHGRRQNPMAQRDSGAARGRRRLR", "length": 1001, "header": "tr|A0A8V1A5J3-1|A0A8V1A5J3_CHICK Isoform 1 of R3H domain containing 2 OS=Gallus gallus OX=9031 GN=R3HDM2 PE=4 SV=1 CANONICAL=A0A8V1A5J3-1" }, "locus": { "chromosome": "34", "start_pos": 1721226, "end_pos": 1698913, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010062249.1", "url": "https://www.ensembl.org/id/ENSGALT00010062249.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038480.1", "url": "https://www.ensembl.org/id/ENSGALP00010038480.1" } ] } }, { "isoform_ac": "A0A8V1A834-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5J3/entry#A0A8V1A834-1", "sequence": { "sequence": 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986, "header": "tr|A0A8V1A834-1|A0A8V1A834_CHICK Computationally mapped isoform of R3H domain containing 2 OS=Gallus gallus OX=9031 GN=R3HDM2 PE=4 SV=1 CANONICAL=A0A8V1A5J3-1" }, "locus": { "chromosome": "34", "start_pos": 1716929, "end_pos": 1698913, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010062257.1", "url": "https://www.ensembl.org/id/ENSGALT00010062257.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038484.1", "url": "https://www.ensembl.org/id/ENSGALP00010038484.1" } ] } }, { "isoform_ac": "A0A8V1AAN7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5J3/entry#A0A8V1AAN7-1", "sequence": { "sequence": "MSNSNTAQESLEIMKETEKKVVEESVSKTKYVSRSPSKEEAEKDGGEEVSVRQEAQSNSKLKLVRSLAVCEESSSPFVDGLLESQDIIQLHVSCPSDKEEEKSTKDGAEKEEKEKNKDKAPRKMLSRDSSQEYTDSTGIDLHEFLVNTLKKNPRDRMMLLKLEQEILEFISDSNNQFKKFPQMTSYHRMLLHRVAAYFGMDHNVDQTGKAVIINKTSNTRIPEQRFSEHIKDEKNAEFPQRFILKRDDTSMDRDDNQDGRRSKSIEEREEEYQRARERIFARETGQNGYLTDSRANRDGLSRASGSRQSSTESEIKSLEPRPWSSTDSDGSIRSLRPPVTKASSFSGISILTRGDSIGSSKGSTASRASRAGLALGAPEACSQPPSSQPSRGLLPCASQQPQPPPPQQPQPQGLPPTAQQQPAMSNHMMSQADELSNPFGQISLSRQGSTEAPDPSSAMFQSSLISQHPQQAGFIMATPGQPIPTSNYSASGHTVPTQQVLQPQGYIQPPQQIQVSYYPPGQYPNSSQQYRSLSHPVAYSSQRTQQLPQQAQQPGLQPMMSNQQQTYQGVMGVQQAQSPGLLNSQRNSMGGQMQSVLGVQQTQPPSLLSSQRSGMGSQMQGLMVQYTPLPSYQVPVANESQSVVQQPFQQPVLVPASQSVQGGLQTGGVPIYYSVIPTAQQNGTSPSVGFLQPPGSEQYQLPQSPSPCSPSQMQQQYSGVSPSGPGVVVMQLNVPNGPQPPQNAPVVQWSHCKYYSLEQRGQKPGDLYNPDSSGQASTQLSSPITSPTQSPTPSPVTNLNSVCTGLSPLPVLTQFPRPMGAAQGDGRYSLLGQPLQYNLSICPPPAAPQPAQLQRTPGAERAEARQPQQEADPQVSIHRPGDERCSAGPGAGGDGPPGGHHADGGGQTLHSALHGRRQNPMAQRDSGAARGRRRLR", "length": 936, "header": "tr|A0A8V1AAN7-1|A0A8V1AAN7_CHICK Computationally mapped isoform of R3H domain containing 2 OS=Gallus gallus OX=9031 GN=R3HDM2 PE=4 SV=1 CANONICAL=A0A8V1A5J3-1" }, "locus": { "chromosome": "34", "start_pos": 1716929, "end_pos": 1698913, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010062253.1", "url": "https://www.ensembl.org/id/ENSGALT00010062253.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038482.1", "url": "https://www.ensembl.org/id/ENSGALP00010038482.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 857, "start_aa": "Thr", "end_pos": 857, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr857", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A5J3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5J3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "nucleic acid binding", "id": "GO:0003676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A5J3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5J3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 273, "end_pos": 275, "annotation": "n_glycosylation_sequon" }, { "start_pos": 552, "end_pos": 554, "annotation": "n_glycosylation_sequon" }, { "start_pos": 590, "end_pos": 592, "annotation": "n_glycosylation_sequon" }, { "start_pos": 703, "end_pos": 705, "annotation": "n_glycosylation_sequon" }, { "start_pos": 747, "end_pos": 749, "annotation": "n_glycosylation_sequon" }, { "start_pos": 903, "end_pos": 905, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1A5J3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5J3" }, { "id": "PS51061", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51061" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "R3H", "eco_id": "ECO_0000259", "start_pos": 215, "end_pos": 278, "start_aa": "Arg", "end_aa": "Thr", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1A5J3", "database": 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"table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A5L0-1", "uniprot_ac": "A0A8V1A5L0", "uniprot_id": "A0A8V1A5L0_CHICK", "mass": { "chemical_mass": 40355.0, "monoisotopic_mass": 40355.0 }, "refseq": {}, "gene_names": [ { "name": "MVB12B", "type": "recommended", "evidence": [ { "id": "A0A8V1A5L0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5L0" } ] } ], "protein_names": [ { "name": "Multivesicular body subunit 12B", "type": "synonym", "evidence": [ { "id": "A0A8V1A5L0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5L0/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFV1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFV1#function" }, { "database": "UniProtKB", "id": "ARBA00053101", "url": "https://www.uniprot.org/uniprotkb/ARBA00053101#function" }, { "database": "UniProtKB", "id": "A0A8V1AFV6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFV6#function" }, { "database": "UniProtKB", "id": "F1P3Y0", "url": "https://www.uniprot.org/uniprotkb/F1P3Y0#function" }, { "database": "UniProtKB", "id": "A0A8V1AAH4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAH4#function" }, { "database": "UniProtKB", "id": "A0A8V1A5L0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5L0#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A5L0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5L0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MVB12B", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5L0", "locus": { "chromosome": "17", "start_pos": 10623399, "end_pos": 10570760, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027775", "url": "https://www.ensembl.org/id/ENSGALG00010027775" } ] } } ], "crossref": [ { "id": "A0A8V1A5L0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A5L0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000000950", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000000950", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "417092", "url": "https://www.ncbi.nlm.nih.gov/gene/417092", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR023340", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023340", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023341", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023341", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040297", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040297", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:417092", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417092", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CFCLKRG", "url": "https://omabrowser.org/oma/group/CFCLKRG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A5L0", "url": "https://www.orthodb.org/?gene=A0A8V1A5L0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AAH4", "url": "https://www.orthodb.org/?gene=A0A8V1AAH4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AFV1", "url": "https://www.orthodb.org/?gene=A0A8V1AFV1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AFV6", "url": "https://www.orthodb.org/?gene=A0A8V1AFV6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1P3Y0", "url": "https://www.orthodb.org/?gene=F1P3Y0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31547", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31547", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31547:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31547:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A5L0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5L0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A5L0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5L0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AAH4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAH4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AAH4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAH4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFV1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFV1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFV1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFV1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFV6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFV6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFV6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFV6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1P3Y0", "url": "https://www.uniprot.org/uniprotkb/F1P3Y0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1P3Y0-1", "url": "https://www.uniprot.org/uniprotkb/F1P3Y0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPCPAVCLPARLQQRSCQVLPLDLQCWGVLGQSCLSEGPCPAAAAGGYARAGAPILFHELFGQLSSPPASSNSISPRWDQSTMPEVRDLSDALPDVPMDPITGVGVVASRSRAPTGYDVVAQTADGLDADLWKDGLFKSKVTRYLCFTRSFSKENSHLGNVLVDMKLIDIKDTLPLGFIPIQETVDTQETAFRKKRLCIKFIPRDSTEAAICDIRILGRSKQAPPQYTFIGELNNMGIWYRMGRVPRNHESSQPAAPSQAPSPTPAPSLPRHISLTLPASFRGKSHSSRLDLEHQHSNLYAISAMDGVPFMISEKFACAPEGMQPIDLLGITIKTLAEIEKEYDYSFRTEQSAAARLPPSPTRCPPVPPS", "length": 370, "header": "tr|A0A8V1A5L0-1|A0A8V1A5L0_CHICK Isoform 1 of Multivesicular body subunit 12B OS=Gallus gallus OX=9031 GN=MVB12B PE=1 SV=1 CANONICAL=A0A8V1A5L0-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A5L0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5L0/entry#A0A8V1A5L0-1", "sequence": { "sequence": "MPCPAVCLPARLQQRSCQVLPLDLQCWGVLGQSCLSEGPCPAAAAGGYARAGAPILFHELFGQLSSPPASSNSISPRWDQSTMPEVRDLSDALPDVPMDPITGVGVVASRSRAPTGYDVVAQTADGLDADLWKDGLFKSKVTRYLCFTRSFSKENSHLGNVLVDMKLIDIKDTLPLGFIPIQETVDTQETAFRKKRLCIKFIPRDSTEAAICDIRILGRSKQAPPQYTFIGELNNMGIWYRMGRVPRNHESSQPAAPSQAPSPTPAPSLPRHISLTLPASFRGKSHSSRLDLEHQHSNLYAISAMDGVPFMISEKFACAPEGMQPIDLLGITIKTLAEIEKEYDYSFRTEQSAAARLPPSPTRCPPVPPS", "length": 370, "header": "tr|A0A8V1A5L0-1|A0A8V1A5L0_CHICK Isoform 1 of Multivesicular body subunit 12B OS=Gallus gallus OX=9031 GN=MVB12B PE=1 SV=1 CANONICAL=A0A8V1A5L0-1" }, "locus": { "chromosome": "17", "start_pos": 10615443, "end_pos": 10574790, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067316.1", "url": "https://www.ensembl.org/id/ENSGALT00010067316.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041189.1", "url": "https://www.ensembl.org/id/ENSGALP00010041189.1" } ] } }, { "isoform_ac": "A0A8V1AAH4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5L0/entry#A0A8V1AAH4-1", "sequence": { "sequence": "MPEVRDLSDALPDVPMDPITGVGVVASRSRAPTGYDVVAQTADGLDADLWKDGLFKSKVTRYLCFTRSFSKENSHLGNVLVDMKLIDIKDTLPLGFIPIQETVDTQETAFRKKRLCIKFIPRDSTEAAICDIRILGRSKQAPPQYTFIGELNNMGIWYRMGRVPRNHESSQPAAPSQAPSPTPAPSLPRHISLTLPASFRGKSHSSRLDLEHQHSNLYAISAMDGVPFMISEKFACAPEGMQPIDLLGITIKTLAEIEKEGLSERFWWDARAEITYTLSCALKLPGRAKDTARDVT", "length": 296, "header": "tr|A0A8V1AAH4-1|A0A8V1AAH4_CHICK Computationally mapped isoform of Multivesicular body subunit 12B OS=Gallus gallus OX=9031 GN=MVB12B PE=1 SV=1 CANONICAL=A0A8V1A5L0-1" }, "locus": { "chromosome": "17", "start_pos": 10620488, "end_pos": 10575750, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067319.1", "url": "https://www.ensembl.org/id/ENSGALT00010067319.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041191.1", "url": "https://www.ensembl.org/id/ENSGALP00010041191.1" } ] } }, { "isoform_ac": "A0A8V1AFV1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5L0/entry#A0A8V1AFV1-1", "sequence": { "sequence": "MPEVRDLSDALPDVPMDPITGVGVVASRSRAPTGYDVVAQTADGLDADLWKDGLFKSKVTRYLCFTRSFSKENSHLGNVLVDMKLIDIKDTLPLGFIPIQETVDTQETAFRKKRLCIKFIPRDSTEAAICDIRILGRSKQAPPQYTFIGELNNMGIWYRMGRVPRNHESSQPAAPSQAPSPTPAPSLPRHISLTLPASFRGKSHSSRLDLEHQHSNLYAISAMDGVPFMISEKFACAPEGMQPIDLLGITIKTLAEIEKEVGSQACTEQKLCEICAYLVARTSALWQSSLVFPKSLLVDEVSIESDS", "length": 307, "header": "tr|A0A8V1AFV1-1|A0A8V1AFV1_CHICK Computationally mapped isoform of Multivesicular body subunit 12B OS=Gallus gallus OX=9031 GN=MVB12B PE=1 SV=1 CANONICAL=A0A8V1A5L0-1" }, "locus": { "chromosome": "17", "start_pos": 10612951, "end_pos": 10575750, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067312.1", "url": "https://www.ensembl.org/id/ENSGALT00010067312.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041187.1", "url": "https://www.ensembl.org/id/ENSGALP00010041187.1" } ] } }, { "isoform_ac": "A0A8V1AFV6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5L0/entry#A0A8V1AFV6-1", "sequence": { "sequence": "MPEVRDLSDALPDVPMDPITGVGVVASRSRAPTGYDVVAQTADGLDADLWKDGLFKSKVTRYLCFTRSFSKENSHLGNVLVDMKLIDIKDTLPLGFIPIQETVDTQETAFRKKRLCIKFIPRDSTEAAICDIRILGRSKQAPPQYTFIGELNNMGIWYRMGRVPRNHESSQPAAPSQAPSPTPAPSLPRHISLTLPASFRGKSHSSRLDLEHQHSNLYAISAMDGVPFMISEKFACAPEGMQPIDLLGITIKTLAEIEKEGLMFYPAAGRAASSTLKVWQSRHGLDRELGSV", "length": 292, "header": "tr|A0A8V1AFV6-1|A0A8V1AFV6_CHICK Computationally mapped isoform of Multivesicular body subunit 12B OS=Gallus gallus OX=9031 GN=MVB12B PE=1 SV=1 CANONICAL=A0A8V1A5L0-1" }, "locus": { "chromosome": "17", "start_pos": 10622507, "end_pos": 10575750, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067321.1", "url": "https://www.ensembl.org/id/ENSGALT00010067321.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041192.1", "url": "https://www.ensembl.org/id/ENSGALP00010041192.1" } ] } }, { "isoform_ac": "F1P3Y0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5L0/entry#F1P3Y0-1", "sequence": { "sequence": "MPEVRDLSDALPDVPMDPITGVGVVASRSRAPTGYDVVAQTADGLDADLWKDGLFKSKVTRYLCFTRSFSKENSHLGNVLVDMKLIDIKDTLPLGFIPIQETVDTQETAFRKKRLCIKFIPRDSTEAAICDIRILGRSKQAPPQYTFIGELNNMGIWYRMGRVPRNHESSQPAAPSQAPSPTPAPSLPRHISLTLPASFRGKSHSSRLDLEHQHSNLYAISAMDGVPFMISEKFACAPEGMQPIDLLGITIKTLAEIEKEYDYSFRTEQSAAARLPPSPTRCPPVPPS", "length": 288, "header": "tr|F1P3Y0-1|A0A8V1A5L0_CHICK Computationally mapped isoform of Multivesicular body subunit 12B OS=Gallus gallus OX=9031 GN=MVB12B PE=1 SV=1 CANONICAL=A0A8V1A5L0-1" }, "locus": { "chromosome": "17", "start_pos": 10615443, "end_pos": 10575750, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067318.1", "url": "https://www.ensembl.org/id/ENSGALT00010067318.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041190.1", "url": "https://www.ensembl.org/id/ENSGALP00010041190.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 264, "start_aa": "Thr", "end_pos": 264, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr264", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:417092", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417092", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287AAQ1-1", "protein_name": "Multivesicular body subunit 12B", "gene_name": "MVB12B", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRSCFCVRRSRDPPPPQPPPPPPPQRGTERSTMPEVKDLSEALPETSMDPITGVGVVASRNRAPTGYDVVAQTADGVDADLWKDGLFKSKVTRYLCFTRSFSKENSHLGNVLVDMKLIDIKDTLPVGFIPIQETVDTQEVAFRKKRLCIKFIPRDSTEAAICDIRIMGRTKQAPPQYTFIGELNSMGIWYRMGRVPRNHDSSQPTTPSQSSAAPTPAPNLPRHISLTLPATFRGRNSTRADYEYQHSNLYAISAMDGVPFMISEKFSCVPESMQPFDLLGITIKSLAEIEKEYEYSFRTEQSAAARLPPSPTRCQQIPQS", "length": 320 }, "evidence": [ { "id": "A0A8V1A5L0", "url": "https://omabrowser.org/oma/group/A0A8V1A5L0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0ABK0L6V2-1", "protein_name": "Multivesicular body subunit 12B", "gene_name": "Mvb12b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRLRLRISSDINHSSKAARLSQEKGRYRQDQATMPEVKELSEALPETPMDPITGVGVVASRNRAPTGYDVVAQTADGVDADLWKDGLFKSKVTRYLCFTRSFSKENSHLGNVLVDMKLIDVKDTLPVGFIPIQETVDTQEVVFRKKRLCIKFIPRDSTEAAICDIRIMGRTKQAPPQYTFIGELNSMGIWYRMGRVPRNHDSSQPTTPSQSSAASTPAPNLPRHISLTLPATFRGRNNTSTDYEYQLSNLYAISAMDGVPFMISEKFSCIPESMQPFDLLGITIKSLAEIEKEYEYSFRTEQSAAARLPPSPTRCQQIPQS", "length": 321 }, "evidence": [ { "id": "A0A8V1A5L0", "url": "https://omabrowser.org/oma/group/A0A8V1A5L0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6KAU4-1", "protein_name": "Multivesicular body subunit 12B", "gene_name": "Mvb12b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRSCFCVRRSRDPPPPQPPPPQRGTDQATMPEVKELSEALPETPMDPITGVGVVASRNRAPTGYDVVAQTADGVDADLWKDGLFKSKVTRYLCFTRSFSKENSHLGNVLVDMKLIDVKDTLPVGFIPIQETVDTQEVVFRKKRLCIKFIPRDSTEAAICDIRIMGRTKQAPPQYTFIGELNSMGIWYRMGRVPRNHDSSQPTTPSQSSASSTPAPNLPRHISLTLPATFRGRNNTSTDYEYQLSNLYAISAMDGVPFMISEKFSCIPESMQPFDLLGITIKSLAEIEKEYEYSFRTEQSAAARLPPSPTRCQQIPQS", "length": 317 }, "evidence": [ { "id": "A0A8V1A5L0", "url": "https://omabrowser.org/oma/group/A0A8V1A5L0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9H7P6-1", "protein_name": "Multivesicular body subunit 12B", "gene_name": "MVB12B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRSCFCVRRSRDPPPPQPPPPPPQRGTDQSTMPEVKDLSEALPETSMDPITGVGVVASRNRAPTGYDVVAQTADGVDADLWKDGLFKSKVTRYLCFTRSFSKENSHLGNVLVDMKLIDIKDTLPVGFIPIQETVDTQEVAFRKKRLCIKFIPRDSTEAAICDIRIMGRTKQAPPQYTFIGELNSMGIWYRMGRVPRNHDSSQPTTPSQSSAASTPAPNLPRHISLTLPATFRGRNSTRTDYEYQHSNLYAISAMDGVPFMISEKFSCVPESMQPFDLLGITIKSLAEIEKEYEYSFRTEQSAAARLPPSPTRCQQIPQS", "length": 319 }, "evidence": [ { "id": "A0A8V1A5L0", "url": "https://omabrowser.org/oma/group/A0A8V1A5L0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A5L0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5L0" } ], "pmid": "" }, { "name": "early endosome", "id": "GO:0005769", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005769", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A5L0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5L0" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A5L0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5L0" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A5L0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5L0" } ], "pmid": "" }, { "name": "late endosome membrane", "id": "GO:0031902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031902", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A5L0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5L0" } ], "pmid": "" }, { "name": "late endosome", "id": "GO:0005770", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005770", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A5L0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5L0" } ], "pmid": "" }, { "name": "ESCRT I complex", "id": "GO:0000813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000813", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A5L0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5L0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A5L0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5L0" } ], "pmid": "" }, { "name": "regulation of epidermal growth factor receptor signaling pathway", "id": "GO:0042058", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042058", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A5L0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5L0" } ], "pmid": "" }, { "name": "viral budding", "id": "GO:0046755", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046755", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A5L0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5L0" } ], "pmid": "" }, { "name": "virus maturation", "id": "GO:0019075", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019075", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A5L0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5L0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "lipid binding", "id": "GO:0008289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008289", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A5L0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5L0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1A5L0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5L0" }, { "id": "PS51498", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51498" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "MABP", "eco_id": "ECO_0000259", "start_pos": 98, "end_pos": 244, "start_aa": "Met", "end_aa": "Arg", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1A5L0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5L0" }, { "id": "PS51497", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51497" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "UMA", "eco_id": "ECO_0000259", "start_pos": 305, "end_pos": 354, "start_aa": "Met", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 264 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 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"A0A8V1A5M6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5M6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 300, "end_pos": 302, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1A5M6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5M6" }, { "id": "PS50009", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50009" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ras-GEF", "eco_id": "ECO_0000259", "start_pos": 174, "end_pos": 410, "start_aa": "Glu", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], 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"count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { 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GN=SAPCD2 PE=4 SV=1 CANONICAL=A0A8V1A5M7-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A5M7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5M7/entry#A0A8V1A5M7-1", "sequence": { "sequence": "MAPERGSRPSPPGPSPAGTEGLPRAFLQSLRTLFDILDDRRRGYVHLREIESRWQGAEARELPAGVLDGLRRAAPPSGYLTFERFVLGLRAALPGADGGVPGKGRAPGRGRGEPRDRERDKERDKERGRGTAVSASRSLEKLPSPHGNEERRGQNGGHREPEPGQGQPRGRGTDVKSAGQSQGDGGHAGPGDVRRHQRGRAEHRRHTIANGVDFGMLKHMKELEQEKDFLLQGLEMVERAREWYHQHIHFMQERQRLLGKNKTSTDFLPDGSQSHLGHLIPKLQEVNRCLGELLSAVGKPGNPTSALSRLAPTAPVASPASAGTQQAINMLKEQNRLLTKEVTDKSERITQLEQEKSALIKQLFEARARSNHEMNQLDSTFI", "length": 382, "header": "tr|A0A8V1A5M7-1|A0A8V1A5M7_CHICK Isoform 1 of Suppressor APC domain containing 2 OS=Gallus gallus OX=9031 GN=SAPCD2 PE=4 SV=1 CANONICAL=A0A8V1A5M7-1" }, "locus": { "chromosome": "17", "start_pos": 1064629, "end_pos": 1053243, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067360.1", "url": "https://www.ensembl.org/id/ENSGALT00010067360.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041204.1", "url": "https://www.ensembl.org/id/ENSGALP00010041204.1" } ] } }, { "isoform_ac": "A0A8V1AFW7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5M7/entry#A0A8V1AFW7-1", "sequence": { "sequence": "MAPERGSRPSPPGPSPAGTEGLPRAFLQSLRTLFDILDDRRRGYVHLREIESRWQGAEARELPAGVLDGLRRAAPPSGYLTFERFVLGLRAALPGADGGVPGKGRAPGRGRGEPRDRERDKERDKERGRGTAVSASRSLEKLPSPHGNEERRGQNGGHREPEPGQGQPRGRGTDVKSAGQSQGDGGHAGPGDVRRHQRGRAEHRRHTIANGVDFGMLKHMKELEQEKDFLLQGLEMVERAREWYHQHIHFMQERQRLLGKNKTSTDFLPDGSQSHLGHLIPKLQEVNRCLGELLSAVGKPGNPTSALSRLAPTAPVASPASAGTQQAINMLKEQNRLLTKEVTDKSERITQLEQEKSALIKQLFEAPVVDEP", "length": 372, "header": "tr|A0A8V1AFW7-1|A0A8V1AFW7_CHICK Computationally mapped isoform of Suppressor APC domain containing 2 OS=Gallus gallus OX=9031 GN=SAPCD2 PE=4 SV=1 CANONICAL=A0A8V1A5M7-1" }, "locus": { "chromosome": "17", "start_pos": 1065334, "end_pos": 1053243, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067357.1", "url": "https://www.ensembl.org/id/ENSGALT00010067357.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041202.1", "url": "https://www.ensembl.org/id/ENSGALP00010041202.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "apical cortex", "id": "GO:0045179", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045179", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A5M7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5M7" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A5M7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5M7" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A5M7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5M7" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A5M7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5M7" } ], "pmid": "" }, { "name": "apical junction complex", "id": "GO:0043296", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043296", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A5M7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5M7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "positive regulation of cell population proliferation", "id": "GO:0008284", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008284", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A5M7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5M7" } ], "pmid": "" }, { "name": "negative regulation of protein localization to cell cortex", "id": "GO:1904777", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904777", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A5M7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5M7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 261, "end_pos": 263, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1A5M7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5M7" }, { "id": "PF25825", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25825" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Suppressor APC", "eco_id": "ECO_0000259", "start_pos": 21, "end_pos": 93, "start_aa": "Gly", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 261, "end_pos": 263 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A5N7-1", "uniprot_ac": "A0A8V1A5N7", "uniprot_id": "A0A8V1A5N7_CHICK", "mass": { "chemical_mass": 63121.0, "monoisotopic_mass": 63121.0 }, "refseq": { "ac": "XP_015155510", "name": "RNA-binding protein MEX3D", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015155510" }, "gene_names": [ { "name": "MEX3D", "type": "recommended", "evidence": [ { "id": "A0A8V1A5N7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5N7" } ] }, { "name": "MEX3D", "type": "synonym", "evidence": [ { "id": "XP_015155510", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015155510" } ] } ], "protein_names": [ { "name": "Mex-3 RNA binding family member D", "type": "synonym", "evidence": [ { "id": "A0A8V1A5N7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5N7/entry#names_and_taxonomy" } ] }, { "name": "RNA-binding protein MEX3D", "type": "synonym", "evidence": [ { "id": "XP_015155510", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015155510" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052559.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015155510.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015155510", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015155510" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A5N7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5N7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MEX3D", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5N7", "locus": { "chromosome": "28", "start_pos": 2895422, "end_pos": 2887161, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027811", "url": "https://www.ensembl.org/id/ENSGALG00010027811" } ] } } ], "crossref": [ { "id": "A0A8V1A5N7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A5N7", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd16723", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16723", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd22423", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22423", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd22424", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22424", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "420082", "url": "https://www.ncbi.nlm.nih.gov/gene/420082", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004088", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004088", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036612", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036612", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047226", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047226", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047227", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047227", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047228", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047228", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:420082", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420082", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KNSRECM", "url": "https://omabrowser.org/oma/group/KNSRECM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A5N7", "url": "https://www.orthodb.org/?gene=A0A8V1A5N7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ADC1", "url": "https://www.orthodb.org/?gene=A0A8V1ADC1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23285", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23285", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23285:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23285:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00013", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00013", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13920", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13920", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015155510", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015155510", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1A5N7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5N7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A5N7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5N7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ADC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADC1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ADC1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADC1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPGSIYQPDGGEAARAPPRCLALLSPPPPPPSTVSTGQEPEPETETREGPPPTQDEALRFALDQLSLLGLEETAEPGGGGGGGGGGGGGGGGEAEPEPPGNSPTLPGTSSPPSSSSSSSVFGNFVAPQNHHHHHNHHHHHHHHLPPLLSDQMNLVGNRKKSVNMTECVPVPSSEHVAEIVGRQGCKIKALRAKTNTYIKTPVRGEEPIFIVTGRKEDVEMAKREILSAAEHFSMIRATRNKVNGLTGALQGPPNLPGQTTIQVRVPYRVVGLVVGPKGATIKRIQQQTHTYIVTPSRDKEPVFEVTGMPENVDRAREEIEAHITMRTGSFVDVNADNDFHTNGTDVCLDLQGGSAGLWAKAPHPARRPAAALRNDSLSSLGSASTESFYSGRVADNSPTSPYSTGGGFTFSDAPAPLGSEECDFGFDFLALDLTTPSAAAAIWSPFERAANPLQAFGGSQRRNSGTATPRHSPTLPDSAGGALEHPLARRIQSNPVSTLSWLPTQGSLSSFSTSTGYSSSSSLPGSVSAASGSPTDSSSSDGHRKSSRECMVCFESEVIAALVPCGHNLFCMECAMRICGKAEPECPACHTPATQAIHIFS", "length": 601, "header": "tr|A0A8V1A5N7-1|A0A8V1A5N7_CHICK Isoform 1 of Mex-3 RNA binding family member D OS=Gallus gallus OX=9031 GN=MEX3D PE=4 SV=1 CANONICAL=A0A8V1A5N7-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A5N7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5N7/entry#A0A8V1A5N7-1", "sequence": { "sequence": "MPGSIYQPDGGEAARAPPRCLALLSPPPPPPSTVSTGQEPEPETETREGPPPTQDEALRFALDQLSLLGLEETAEPGGGGGGGGGGGGGGGGEAEPEPPGNSPTLPGTSSPPSSSSSSSVFGNFVAPQNHHHHHNHHHHHHHHLPPLLSDQMNLVGNRKKSVNMTECVPVPSSEHVAEIVGRQGCKIKALRAKTNTYIKTPVRGEEPIFIVTGRKEDVEMAKREILSAAEHFSMIRATRNKVNGLTGALQGPPNLPGQTTIQVRVPYRVVGLVVGPKGATIKRIQQQTHTYIVTPSRDKEPVFEVTGMPENVDRAREEIEAHITMRTGSFVDVNADNDFHTNGTDVCLDLQGGSAGLWAKAPHPARRPAAALRNDSLSSLGSASTESFYSGRVADNSPTSPYSTGGGFTFSDAPAPLGSEECDFGFDFLALDLTTPSAAAAIWSPFERAANPLQAFGGSQRRNSGTATPRHSPTLPDSAGGALEHPLARRIQSNPVSTLSWLPTQGSLSSFSTSTGYSSSSSLPGSVSAASGSPTDSSSSDGHRKSSRECMVCFESEVIAALVPCGHNLFCMECAMRICGKAEPECPACHTPATQAIHIFS", "length": 601, "header": "tr|A0A8V1A5N7-1|A0A8V1A5N7_CHICK Isoform 1 of Mex-3 RNA binding family member D OS=Gallus gallus OX=9031 GN=MEX3D PE=4 SV=1 CANONICAL=A0A8V1A5N7-1" }, "locus": { "chromosome": "28", "start_pos": 2894191, "end_pos": 2887228, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067379.1", "url": "https://www.ensembl.org/id/ENSGALT00010067379.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041214.1", "url": "https://www.ensembl.org/id/ENSGALP00010041214.1" } ] } }, { "isoform_ac": "A0A8V1ADC1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5N7/entry#A0A8V1ADC1-1", "sequence": { "sequence": "MPGSIYQPDGGEAARAPPRCLALLSPPPPPPSTVSTGQEPEPETETREGPPPTQDEALRFALDQLSLLGLEETAEPGGGGGGGGGGGGGGGGEAEPEPPGNSPTLPGTSSPPSSSSSSSVFGNFVAPQNHHHHHNHHHHHHHHLPPLLSDQMNLVGNRKKSVNMTECVPVPSSEHVAEIVGRQGCKIKALRAKTNTYIKTPVRGEEPIFIVTGRKEDVEMAKREILSAAEHFSMIRATRNKVNGLTGALQGPPNLPGQTTIQTHTYIVTPSRDKEPVFEVTGMPENVDRAREEIEAHITMRTGSFVDVNADNDFHTNGTDVCLDLQGGSAGLWAKAPHPARRPAAALRNDSLSSLGSASTESFYSGRVADNSPTSPYSTGGGFTFSDAPAPLGSEECDFGFDFLALDLTTPSAAAAIWSPFERAANPLQAFGGSQRRNSGTATPRHSPTLPDSAGGALEHPLARRIQSNPVSTLSWLPTQGSLSSFSTSTGYSSSSSLPGSVSAASGSPTDSSSSDGHRKSSRECMVCFESEVIAALVPCGHNLFCMECAMRICGKAEPECPACHTPATQAIHIFS", "length": 576, "header": "tr|A0A8V1ADC1-1|A0A8V1ADC1_CHICK Computationally mapped isoform of Mex-3 RNA binding family member D OS=Gallus gallus OX=9031 GN=MEX3D PE=4 SV=1 CANONICAL=A0A8V1A5N7-1" }, "locus": { "chromosome": "28", "start_pos": 2894191, "end_pos": 2887228, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067378.1", "url": "https://www.ensembl.org/id/ENSGALT00010067378.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041213.1", "url": "https://www.ensembl.org/id/ENSGALP00010041213.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:420082", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420082", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1MAZ0-1", "protein_name": "Mex-3 RNA binding family member D", "gene_name": "MEX3D", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPSSTGQPDGGGGARGSGPGAPVCGDPSPGPPPPPPPPPPPEGADEAAPAPRPPPEPDDAAAALRLALDQLSGLGLGGAGDQDEEGATAGGGDGAGAATGGADGGAAAEPAPPDGPETGAPGVAVAPGPLPLLEPDVSPPPPPRPSPPDVFAGFAPHPAALGPPTLLAEQMSVIGSRKKSVNMTECVPVPSSEHVAEIVGRQGCKIKALRAKTNTYIKTPVRGEEPVFIVTGRKEDVEMAKREILSAAEHFSVIRATRSKAGGLPGTAQGPPNLPGQTTIQVRVPYRVVGLVVGPKGATIKRIQQRTHTYIVTPGRDKEPVFAVTGMPENVDRAREEIEAHITLRTGAFTDASPDSDFHSNGTDVCLDLLGAAAGLWAKAPNPGRRPPAPTASLRGDTALGAPGGPESFYAASRGGPPVPVQVPDAGPASPYSTSGNGGFTFGGDGPGAPTGPPALEDCDFGFDFLALDLTVPTAATIWAPFERATPLPAFGGCSAVNGAPAPPAPGARRSSGTGTPRHSPTLPEPGGLGLELPLARRPTPDPVGALPWRPPQGSLTSFSSSASFSTATSLPSSSSASSCSALDSSAPENGRKPPAAPAPAALARECVVCAEGEVMAALVPCGHNLFCMDCAVRICGKSEPECPACRTPATQAIHIFS", "length": 658 }, "evidence": [ { "id": "A0A8V1A5N7", "url": "https://omabrowser.org/oma/group/A0A8V1A5N7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1M5V7-1", "protein_name": "Mex-3 RNA binding family member D", "gene_name": "Mex3d", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPGSTGQPDAGGTGTGTTAGDPGHPHPALAGAEDAAPRPPPEPDDAAAALRLALDQLSALGLGDARPGDEGMATRSADGATERGEDEPVPPDELEAAVAPPVTGAPSMGVGPSMAVAPSVTCAPSMALAPSVTSAASMAVAPSVTCAPCMAVAPSVTVAPSMALTPSVTLAPTMAVASPVAPGGLPLLDPDVSPRPSPPDVFASFAPHPAALGPSTLLAEQLNVIGSRKKSVNMTECVPVPSSEHVAEIVGRQGCKIKALRAKTNTYIKTPVRGEEPVFIVTGRKEDVEMAKREILSAAEHFSLIRATRSKAGGLSGATPGPPNLPGQTTIQVRVPYRVVGLVVGPKGATIKRIQQRTHTYIVTPGRDKEPVFAVTGMPENVDRAREEIEAHITLRTGAFTDAGPDSDFHANGTDVCLDLLGAAASLWAKAPHPGRRPPTATGGLRGDNALGAASTPEPFYVGSRGGPALPDPSPSSPYGGSGNGGFTFGGDGPGAPTGTTTPEDCDFGFDFLALDLTVPATATIWAPFERAAPLPAFSGCPTVNGAPAQPNTGTRRSSGGGGAATTPRHSPTLPEPGGLSLELPLARRGVPDPVGAVPWRPPQSTLPPFSGSTTFSTTPSLPSTTPASSTMDTVPSEGNHKPSTTAANSSASAAAPGPPAAALARECVVCSEGEAMAALVPCGHNLFCMDCAVRICGKSEPECPACRTPATQAIHIFSYLRPSGSASVLDK", "length": 732 }, "evidence": [ { "id": "A0A8V1A5N7", "url": "https://omabrowser.org/oma/group/A0A8V1A5N7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q3UE17-1", "protein_name": "RNA-binding protein MEX3D", "gene_name": "Mex3d", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPGSTGQPDAGGAGTGTTAGDPGHPHPALAGAEDAAPRPPPEPDDAAAALRLALDQLSALGLGGARPGDEGMATRSADGATECGEDEPAPPDELEVAVAPPVTASVAPGGLPLLDPDVSPRPSPPDVFASFAPHPAALGPSTLLAEQLNVIGSRKKSVNMTECVPVPSSEHVAEIVGRQGCKIKALRAKTNTYIKTPVRGEEPVFIVTGRKEDVEMAKREILSAEHFSLIRATRSKAGGLSGATPGPPNLPGQTTIQVRVPYRVVGLVVGPKGATIKRIQQRTHTYIVTPGRDKEPVFAVTGMPENVDRAREEIEAHITLRTGAFTDSGPDSDFHANGTDVCLDLLGAAASLWAKAPHPGRRPPAATGGLRGDNALGAASTPEPFYVGSRGGPPLPDPSPSSPYGGSGNGGFTFGGDGPSAPTGTATPEDCDFGFDFLALDLTVPATATIWAPFERAAPLPAFSGCPAVNGAPAQPNTGTRRSSGGGAATTPRHSPTLPEPGGLSLELPLARRSVPDPVGAVPWRPPQSALPPFSGSTTFSTTPSLPSTTLASSTLDTVPSEGNHKPSTTAANSSASTAAPGPPSAALARECVVCSEGEAMAALVPCGHNLFCMDCAVRICGKSEPECPACRTPATQAIHIFS", "length": 643 }, "evidence": [ { "id": "A0A8V1A5N7", "url": "https://omabrowser.org/oma/group/A0A8V1A5N7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q86XN8-1", "protein_name": "RNA-binding protein MEX3D", "gene_name": "MEX3D", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPSSLGQPDGGGGGGGGGGGVGAAGEDPGPGPAPPPEGAQEAAPAPRPPPEPDDAAAALRLALDQLSALGLGGAGDTDEEGAAGDGAAAAGGADGGAAPEPVPPDGPEAGAPPTLAPAVAPGSLPLLDPNASPPPPPPPRPSPPDVFAGFAPHPAALGPPTLLADQMSVIGSRKKSVNMTECVPVPSSEHVAEIVGRQGCKIKALRAKTNTYIKTPVRGEEPVFIVTGRKEDVEMAKREILSAAEHFSIIRATRSKAGGLPGAAQGPPNLPGQTTIQVRVPYRVVGLVVGPKGATIKRIQQRTHTYIVTPGRDKEPVFAVTGMPENVDRAREEIEAHITLRTGAFTDAGPDSDFHANGTDVCLDLLGAAASLWAKTPNQGRRPPTATAGLRGDTALGAPSAPEAFYAGSRGGPSVPDPGPASPYSGSGNGGFAFGAEGPGAPVGTAAPDDCDFGFDFDFLALDLTVPAAATIWAPFERAAPLPAFSGCSTVNGAPGPPAAGARRSSGAGTPRHSPTLPEPGGLRLELPLSRRGAPDPVGALSWRPPQGPVSFPGGAAFSTATSLPSSPAAAACAPLDSGASENSRKPPSASSAPALARECVVCAEGEVMAALVPCGHNLFCMDCAVRICGKSEPECPACRTPATQAIHIFS", "length": 651 }, "evidence": [ { "id": "A0A8V1A5N7", "url": "https://omabrowser.org/oma/group/A0A8V1A5N7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A5N7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5N7" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A5N7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5N7" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A5N7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5N7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A5N7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5N7" } ], "pmid": "" }, { "name": "mRNA 3'-UTR AU-rich region binding", "id": "GO:0035925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035925", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A5N7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5N7" } ], "pmid": "" }, { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A5N7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5N7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 163, "end_pos": 165, "annotation": "n_glycosylation_sequon" }, { "start_pos": 342, "end_pos": 344, "annotation": "n_glycosylation_sequon" }, { "start_pos": 374, "end_pos": 376, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1A5N7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5N7" }, { "id": "PS50089", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50089" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RING-type", "eco_id": "ECO_0000259", "start_pos": 550, "end_pos": 590, "start_aa": "Cys", "end_aa": "His", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 163, "end_pos": 165 }, { "start_pos": 342, "end_pos": 344 }, { "start_pos": 374, "end_pos": 376 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A5Q1-1", "uniprot_ac": "A0A8V1A5Q1", "uniprot_id": "A0A8V1A5Q1_CHICK", "mass": { "chemical_mass": 25294.0, "monoisotopic_mass": 25294.0 }, "refseq": {}, "gene_names": [ { "name": "NMRK2", "type": "recommended", "evidence": [ { "id": "A0A8V1A5Q1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5Q1" } ] } ], "protein_names": [ { "name": "Nicotinamide riboside kinase 2", "type": "synonym", "evidence": [ { "id": "A0A8V1A5Q1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5Q1/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A5Q1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5Q1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NMRK2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5Q1", "locus": { "chromosome": "28", "start_pos": 1893839, "end_pos": 1900223, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027821", "url": "https://www.ensembl.org/id/ENSGALG00010027821" } ] } } ], "crossref": [ { "id": "A0A8V1A5Q1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A5Q1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000025751", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000025751", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd02024", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02024", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100858798", "url": "https://www.ncbi.nlm.nih.gov/gene/100858798", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:100858798", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100858798", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1A5Q1", "url": "https://www.orthodb.org/?gene=A0A8V1A5Q1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "R4GJ92", "url": "https://www.orthodb.org/?gene=R4GJ92", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10285", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10285", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13238", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13238", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-196807", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-196807", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "14017", "url": "https://www.rhea-db.org/rhea/14017", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "25568", "url": "https://www.rhea-db.org/rhea/25568", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1A5Q1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5Q1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A5Q1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5Q1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "R4GJ92", "url": "https://www.uniprot.org/uniprotkb/R4GJ92", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "R4GJ92-1", "url": "https://www.uniprot.org/uniprotkb/R4GJ92-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAAPLPSAPQRPPARGKRRTVGSVTNGGKTTLTNRIVKALPNCCVIHQDDFFKPQDQIEVGEDGFKQWDVLDSLDMEAMVSTVRAWMENPVKFARSHGVNVTPDPTEPPSKEPHILLIEGFLLYNYRPLMELFDLRYFLAVPYDECKRRRSTRSYTVPDPPGLFDGHVWPMYLKHRKEMEDSGVDVVYLDGLKSREELYNEVLEDIRNRLLNRPPGPQKS", "length": 221, "header": "tr|A0A8V1A5Q1-1|A0A8V1A5Q1_CHICK Isoform 1 of Nicotinamide riboside kinase 2 OS=Gallus gallus OX=9031 GN=NMRK2 PE=3 SV=1 CANONICAL=A0A8V1A5Q1-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A5Q1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5Q1/entry#A0A8V1A5Q1-1", "sequence": { "sequence": "MAAAPLPSAPQRPPARGKRRTVGSVTNGGKTTLTNRIVKALPNCCVIHQDDFFKPQDQIEVGEDGFKQWDVLDSLDMEAMVSTVRAWMENPVKFARSHGVNVTPDPTEPPSKEPHILLIEGFLLYNYRPLMELFDLRYFLAVPYDECKRRRSTRSYTVPDPPGLFDGHVWPMYLKHRKEMEDSGVDVVYLDGLKSREELYNEVLEDIRNRLLNRPPGPQKS", "length": 221, "header": "tr|A0A8V1A5Q1-1|A0A8V1A5Q1_CHICK Isoform 1 of Nicotinamide riboside kinase 2 OS=Gallus gallus OX=9031 GN=NMRK2 PE=3 SV=1 CANONICAL=A0A8V1A5Q1-1" }, "locus": { "chromosome": "28", "start_pos": 1898442, "end_pos": 1894105, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067411.1", "url": "https://www.ensembl.org/id/ENSGALT00010067411.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041224.1", "url": "https://www.ensembl.org/id/ENSGALP00010041224.1" } ] } }, { "isoform_ac": "R4GJ92-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5Q1/entry#R4GJ92-1", "sequence": { "sequence": "MEYIIGIGGVTNGGKTTLTNRIVKALPNCCVIHQDDFFKPQDQIEVGEDGFKQWDVLDSLDMEAMVSTVRAWMENPVKFARSHGVNVTPDPTEPPSKEPHILLIEGFLLYNYRPLMELFDLRYFLAVPYDECKRRRSTRSYTVPDPPGLFDGHVWPMYLKHRKEMEDSGVDVVYLDGLKSREELYNEVLEDIRNRLLNRPPGPQKS", "length": 206, "header": "tr|R4GJ92-1|A0A8V1A5Q1_CHICK Computationally mapped isoform of Nicotinamide riboside kinase 2 OS=Gallus gallus OX=9031 GN=NMRK2 PE=3 SV=2 CANONICAL=A0A8V1A5Q1-1" }, "locus": { "chromosome": "28", "start_pos": 1899689, "end_pos": 1894105, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067414.1", "url": "https://www.ensembl.org/id/ENSGALT00010067414.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041226.1", "url": "https://www.ensembl.org/id/ENSGALP00010041226.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:100858798", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100858798", "resource": "KEGG Pathway" }, { "id": "R-GGA-196807", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-196807", "resource": "Reactome", "description": "Nicotinate metabolism" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "ribosylnicotinamide kinase activity", "id": "GO:0050262", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050262", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A5Q1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5Q1" } ], "pmid": "" }, { "name": "nicotinate riboside kinase activity", "id": "GO:0061769", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061769", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A5Q1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5Q1" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A5Q1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5Q1" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A5Q1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5Q1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A5Q1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5Q1" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A5Q1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5Q1" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A5Q1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5Q1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "NAD+ biosynthetic process via the salvage pathway", "id": "GO:0034355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034355", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A5Q1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5Q1" } ], "pmid": "" }, { "name": "NAD+ metabolic process", "id": "GO:0019674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019674", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A5Q1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5Q1" } ], "pmid": "" }, { "name": "pyridine nucleotide biosynthetic process", "id": "GO:0019363", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019363", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A5Q1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5Q1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 101, "end_pos": 103, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "14017", "name": "", "equation": "beta-nicotinamide D-riboside + ATP = beta-nicotinamide D-ribonucleotide + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "14017", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/14017" } ] }, { "id": "25568", "name": "", "equation": "beta-D-ribosylnicotinate + ATP = nicotinate beta-D-ribonucleotide + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "25568", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/25568" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 101, "end_pos": 103 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A5Q4-1", "uniprot_ac": "A0A8V1A5Q4", "uniprot_id": "A0A8V1A5Q4_CHICK", "mass": { "chemical_mass": 56248.0, "monoisotopic_mass": 56248.0 }, "refseq": {}, "gene_names": [ { "name": "SERPING1", "type": "recommended", "evidence": [ { "id": "A0A8V1A5Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5Q4" } ] } ], "protein_names": [ { "name": "Serpin family G member 1", "type": "synonym", "evidence": [ { "id": "A0A8V1A5Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5Q4/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A5Q4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5Q4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SERPING1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5Q4", "locus": { "chromosome": "5", "start_pos": 16557683, "end_pos": 16561130, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010026291", "url": "https://www.ensembl.org/id/ENSGALG00010026291" } ] } } ], "crossref": [ { "id": "A0A8V1A5Q4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A5Q4", "database": "AlphaFoldDB", "categories": [] }, { "id": "423132", "url": "https://www.ncbi.nlm.nih.gov/gene/423132", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000215", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000215", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023796", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023796", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036186", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036186", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042178", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042178", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042185", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042185", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A5Q4", "url": "https://www.orthodb.org/?gene=A0A8V1A5Q4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A848", "url": "https://www.orthodb.org/?gene=A0A8V1A848", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AAW7", "url": "https://www.orthodb.org/?gene=A0A8V1AAW7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AD33", "url": "https://www.orthodb.org/?gene=A0A8V1AD33", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11461", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11461", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11461:SF159", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11461:SF159", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00079", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00079", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1A5Q4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5Q4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A5Q4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5Q4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A848", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A848", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A848-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A848-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AAW7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAW7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AAW7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAW7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AD33", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD33", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AD33-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD33-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRLRPLPEGRVGGLLTMKLCLLLVCLVATVTATVTPVSTPETTPSGRVKPIRLQPAQTVFPRLWDTGTPTQPVPSSNASTTEEPSLGAVLEALEPLGPVEFVAAPEESGTAANGSVATPEPETTTGPPSTPPDTINPPCPGDEEPAETCWAPTREQKEEVAMALGTFALRFYQHMAESAKPDTNLLFSPVNVALGLSHLLLGARGETQQRLAAILGYQPGLACVHSALQQLVNVSGLLSATEIFHHPDLHLRPRFLNESWRFYKARPRELSGNESLDLQRINEWVRKATHGLVPQLLSQLPDEPRLVLLSAVHFQARWQKPFKTKHTVLLPFMRHGHRPVDVLTMTSKKYPVASFTDPRLQVQVGRLELSGGLSLVVLVPRGPPEALEAVERALDPPTFLALLQRAANTPVRPTTVALPRLHLDLAVDVVAKVHDMDFGLFLDAELCGLAQGPEVAVDAAQHRAVLTLDEKGVEAAGAMATSLARIALQLEALQPFLFVLWDEGNAIPLFMGRLSDPQA", "length": 519, "header": "tr|A0A8V1A5Q4-1|A0A8V1A5Q4_CHICK Isoform 1 of Serpin family G member 1 OS=Gallus gallus OX=9031 GN=SERPING1 PE=1 SV=1 CANONICAL=A0A8V1A5Q4-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A5Q4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5Q4/entry#A0A8V1A5Q4-1", "sequence": { "sequence": "MRLRPLPEGRVGGLLTMKLCLLLVCLVATVTATVTPVSTPETTPSGRVKPIRLQPAQTVFPRLWDTGTPTQPVPSSNASTTEEPSLGAVLEALEPLGPVEFVAAPEESGTAANGSVATPEPETTTGPPSTPPDTINPPCPGDEEPAETCWAPTREQKEEVAMALGTFALRFYQHMAESAKPDTNLLFSPVNVALGLSHLLLGARGETQQRLAAILGYQPGLACVHSALQQLVNVSGLLSATEIFHHPDLHLRPRFLNESWRFYKARPRELSGNESLDLQRINEWVRKATHGLVPQLLSQLPDEPRLVLLSAVHFQARWQKPFKTKHTVLLPFMRHGHRPVDVLTMTSKKYPVASFTDPRLQVQVGRLELSGGLSLVVLVPRGPPEALEAVERALDPPTFLALLQRAANTPVRPTTVALPRLHLDLAVDVVAKVHDMDFGLFLDAELCGLAQGPEVAVDAAQHRAVLTLDEKGVEAAGAMATSLARIALQLEALQPFLFVLWDEGNAIPLFMGRLSDPQA", "length": 519, "header": "tr|A0A8V1A5Q4-1|A0A8V1A5Q4_CHICK Isoform 1 of Serpin family G member 1 OS=Gallus gallus OX=9031 GN=SERPING1 PE=1 SV=1 CANONICAL=A0A8V1A5Q4-1" }, "locus": { "chromosome": "5", "start_pos": 16560952, "end_pos": 16558044, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063982.1", "url": "https://www.ensembl.org/id/ENSGALT00010063982.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039403.1", "url": "https://www.ensembl.org/id/ENSGALP00010039403.1" } ] } }, { "isoform_ac": "A0A8V1A848-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5Q4/entry#A0A8V1A848-1", "sequence": { "sequence": "MKLCLLLVCLVATVTATVTPVSTPETTPSGRVKPIRLQPAQTVFPRLWDTGTPTQPVPSSNASTTEEPSLGAVLEALEPLGPVEFVAAPEESGTAANGSVATPEPETTTGPPSTPPDTINPPCPGDEEPAETCWAPTREQKEEVAMALGTFALRFYQHMAESAKPDTNLLFSPVNVALGLSHLLLGEGLPVVQPTHPRPSRLPGPAEPHYCPQVPAVRPSSAWLPSWGTSQGWPACTAPCSSLSMCQGCSPPQRSSTTQVGRLELSGGLSLVVLVPRGPPEALEAVERALDPPTFLALLQRAANTPVRPTTVALPRLHLDLAVDVVAKVHDMDFGLFLDAELCGLAQGPEVAVDAAQHRAVLTLDEKGVEAAGAMATSLARIALQLEALQPFLFVLWDEGNAIPLFMGRLSDPQA", "length": 415, "header": "tr|A0A8V1A848-1|A0A8V1A848_CHICK Computationally mapped isoform of Serpin family G member 1 OS=Gallus gallus OX=9031 GN=SERPING1 PE=1 SV=1 CANONICAL=A0A8V1A5Q4-1" }, "locus": { "chromosome": "5", "start_pos": 16560469, "end_pos": 16558044, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063971.1", "url": "https://www.ensembl.org/id/ENSGALT00010063971.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039400.1", "url": "https://www.ensembl.org/id/ENSGALP00010039400.1" } ] } }, { "isoform_ac": "A0A8V1AAW7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5Q4/entry#A0A8V1AAW7-1", "sequence": { "sequence": "MKLCLLLVCLVATVTATVTPVSTPETTPSGRVKPIRLQPAQTVFPRLWDTGTPTQPVPSSNASTTEEPSLGAVLEALEPLGPVEFVAAPEESGTAANGSVATPEPETTTGPPSTPPDTINPPCPGDEEPAETCWAPTREQKEEVAMALGTFALRFYQHMAESAKPDTNLLFSPVNVALGLSHLLLGARGETQQRLAAILGYQPGLACVHSALQQLVNVSGLLSATEIFHHPDLHLRPRFLNESWRFYKARPRELSGNESLDLQRINEWVRKATHGLVPQLLSQLPDEPRLVLLSAVHFQARWQKPFKTKHTVLLPFMRHGHRPVDVLTMTSKKYPVASFTDPRLQVQVGRLELSGGLSLVVLVPRGPPEALEAVERALDPPTFLALLQRAANTPVRPTTVALPRLHLDLAVDVVAKVHDMDFGLFLDAELCGLAQGPEVAVDAAQHRAVLTLDEKGVEAAGAMATSLARIALQLEALQPFLFVLWDEGNAIPLFMGRLSDPQA", "length": 503, "header": "tr|A0A8V1AAW7-1|A0A8V1AAW7_CHICK Computationally mapped isoform of Serpin family G member 1 OS=Gallus gallus OX=9031 GN=SERPING1 PE=1 SV=1 CANONICAL=A0A8V1A5Q4-1" }, "locus": { "chromosome": "5", "start_pos": 16560469, "end_pos": 16558044, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063990.1", "url": "https://www.ensembl.org/id/ENSGALT00010063990.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039404.1", "url": "https://www.ensembl.org/id/ENSGALP00010039404.1" } ] } }, { "isoform_ac": "A0A8V1AD33-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5Q4/entry#A0A8V1AD33-1", "sequence": { "sequence": "MKLCLLLVCLVATVTATVTPVSTPETTPSGRVKPIRLQPAQTVFPRLWDTGTPTQPVPSSNASTTEEPSLGAVLEALEPLGPVEFVAAPEESGTAANGSVATPEPETTTGPPSTPPDTINPPCPGDEEPAETCWAPTREQKEEVAMALGTFALRFYQHMAESAKPDTNLLFSPVNVALGLSHLLLGARGETQQRLAAILGYQPGLACVHSALQQLVNVSGLLSATEIFHHPDLHLRPRCLMPAPSFLASISSLPPSFIPAFSSSPFHLSLPLPIPLSLLPHIFSPSPPSFLPSLFTPSFFLPTNLPLATTLQPHPSFLPSPSHTSQFLLPHWVLLAPQQLLCLCSPHQLWA", "length": 351, "header": "tr|A0A8V1AD33-1|A0A8V1AD33_CHICK Computationally mapped isoform of Serpin family G member 1 OS=Gallus gallus OX=9031 GN=SERPING1 PE=1 SV=1 CANONICAL=A0A8V1A5Q4-1" }, "locus": { "chromosome": "5", "start_pos": 16560469, "end_pos": 16557709, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063976.1", "url": "https://www.ensembl.org/id/ENSGALT00010063976.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039402.1", "url": "https://www.ensembl.org/id/ENSGALP00010039402.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 130, "start_aa": "Thr", "end_pos": 130, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr130", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "negative regulation of complement activation, lectin pathway", "id": "GO:0001869", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001869", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A5Q4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5Q4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "serine-type endopeptidase inhibitor activity", "id": "GO:0004867", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004867", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A5Q4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5Q4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A5Q4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5Q4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 113, "end_pos": 115, "annotation": "n_glycosylation_sequon" }, { "start_pos": 233, "end_pos": 235, "annotation": "n_glycosylation_sequon" }, { "start_pos": 257, "end_pos": 259, "annotation": "n_glycosylation_sequon" }, { "start_pos": 273, "end_pos": 275, "annotation": "n_glycosylation_sequon" }, { "start_pos": 77, "end_pos": 79, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1A5Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5Q4" }, { "id": "SM00093", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00093" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Serpin", "eco_id": "ECO_0000259", "start_pos": 169, "end_pos": 517, "start_aa": "Leu", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 130 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 113, "end_pos": 115 }, { "start_pos": 233, "end_pos": 235 }, { "start_pos": 257, "end_pos": 259 }, { "start_pos": 273, "end_pos": 275 }, { "start_pos": 77, "end_pos": 79 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": 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"total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A5R1-1", "uniprot_ac": "A0A8V1A5R1", "uniprot_id": "A0A8V1A5R1_CHICK", "mass": { "chemical_mass": 41061.0, "monoisotopic_mass": 41061.0 }, "refseq": {}, "gene_names": [ { "name": "ATCAY", "type": "recommended", "evidence": [ { "id": "A0A8V1A5R1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5R1" } ] } ], "protein_names": [ { "name": "ATCAY kinesin light chain interacting caytaxin", "type": "synonym", "evidence": [ { "id": "A0A8V1A5R1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5R1/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A5R1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5R1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ATCAY", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5R1", "locus": { "chromosome": "28", "start_pos": 1904772, "end_pos": 1920258, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027831", "url": "https://www.ensembl.org/id/ENSGALG00010027831" } ] } } ], "crossref": [ { "id": "A0A8V1A5R1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A5R1", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00170", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00170", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001251", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001251", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022181", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022181", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036865", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036865", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:420094", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420094", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1A5R1", "url": "https://www.orthodb.org/?gene=A0A8V1A5R1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ADE7", "url": "https://www.orthodb.org/?gene=A0A8V1ADE7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AFZ8", "url": "https://www.orthodb.org/?gene=A0A8V1AFZ8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12112", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12112", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12112:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12112:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12496", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12496", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13716", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13716", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1A5R1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5R1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A5R1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5R1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ADE7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADE7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ADE7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADE7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFZ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFZ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFZ8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGTTEATLRMESVDVKEEWQDEDFPGPLPEETGMESLGSPAEDEHTSSPPHTLNFNGAHRKRKTLVAPEINISLDQSEGSILSDDFLDTPDDLDINVDDIETPDETDSLEFLGNGNELEWEDDTPVATAKNMPGDSADLFGDGGTEDGSATNGRLWRTVIIGEQEHRIDLQMIKPYMRVVTHGGYYGEGLNAIIVFAACYLPDSNLADYHYIMENLFLYVISSLELLVAEDYMIVYLNGATPRRRMPGLGWLKKCYQMIDRRLRKNLKALIIVHPSWFIRTVLAISRPFISVKFINKIQYVHSLEELEQLIPMEHVQIPDCVSQYEEERIKARRERAEEKQDMAERERPVPPAEDQETSMP", "length": 361, "header": "tr|A0A8V1A5R1-1|A0A8V1A5R1_CHICK Isoform 1 of ATCAY kinesin light chain interacting caytaxin OS=Gallus gallus OX=9031 GN=ATCAY PE=4 SV=1 CANONICAL=A0A8V1A5R1-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A5R1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5R1/entry#A0A8V1A5R1-1", "sequence": { "sequence": "MGTTEATLRMESVDVKEEWQDEDFPGPLPEETGMESLGSPAEDEHTSSPPHTLNFNGAHRKRKTLVAPEINISLDQSEGSILSDDFLDTPDDLDINVDDIETPDETDSLEFLGNGNELEWEDDTPVATAKNMPGDSADLFGDGGTEDGSATNGRLWRTVIIGEQEHRIDLQMIKPYMRVVTHGGYYGEGLNAIIVFAACYLPDSNLADYHYIMENLFLYVISSLELLVAEDYMIVYLNGATPRRRMPGLGWLKKCYQMIDRRLRKNLKALIIVHPSWFIRTVLAISRPFISVKFINKIQYVHSLEELEQLIPMEHVQIPDCVSQYEEERIKARRERAEEKQDMAERERPVPPAEDQETSMP", "length": 361, "header": "tr|A0A8V1A5R1-1|A0A8V1A5R1_CHICK Isoform 1 of ATCAY kinesin light chain interacting caytaxin OS=Gallus gallus OX=9031 GN=ATCAY PE=4 SV=1 CANONICAL=A0A8V1A5R1-1" }, "locus": { "chromosome": "28", "start_pos": 1917947, "end_pos": 1908256, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067450.1", "url": "https://www.ensembl.org/id/ENSGALT00010067450.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041234.1", "url": "https://www.ensembl.org/id/ENSGALP00010041234.1" } ] } }, { "isoform_ac": "A0A8V1ADE7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5R1/entry#A0A8V1ADE7-1", "sequence": { "sequence": "MGTTEATLRMESVDVKEEWQDEDFPGPLPEETGMESLGSPAEDEHTSSPPHTLNFNGAHRKRKTLVAPEINISLDQSEGSILSDDFLDTPDDLDINVDDIETPDETDSLEFLGNGNELEWEDDTPVATAKNMPGDSADLFGDGGTEDGSATNGRLWRTVIIGEQEHRIDLQMIKPYMRVVTHGGYYGEGLNAIIVFAACYLPDSNLADYHYIMENLFLYVISSLELLVAEDYMIVYLNGATPRRRMPGLGWLKKCYQMIDRRLRKNLKALIIVHPSWFIRTVLAISRPFISVKFINKIQYVHSLEELEQLIPMEHVQIPDCVSQYEEERIKARRERAEEKQDMAERESRPVPPAEDQETRLDHPFPSASPLLWGFIAFVVCNVNSSTCATWPMRASSQNLNFGWRGRWRCPSSTHSMGAPHLPSGPGLLWGWGTHGGPWDALRVPLLPRSELSVSPQESP", "length": 460, "header": "tr|A0A8V1ADE7-1|A0A8V1ADE7_CHICK Computationally mapped isoform of ATCAY kinesin light chain interacting caytaxin OS=Gallus gallus OX=9031 GN=ATCAY PE=4 SV=1 CANONICAL=A0A8V1A5R1-1" }, "locus": { "chromosome": "28", "start_pos": 1917947, "end_pos": 1908531, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067447.1", "url": "https://www.ensembl.org/id/ENSGALT00010067447.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041233.1", "url": "https://www.ensembl.org/id/ENSGALP00010041233.1" } ] } }, { "isoform_ac": "A0A8V1AFZ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5R1/entry#A0A8V1AFZ8-1", "sequence": { "sequence": "MLSVLSVLSVLSVLAVLSVLAVLSVLSVLSCSLCSLCSLCPLCTHRIPRGAAGVAQQLWAQCCSSRSRRAAPLREPRCGGRQSGGAVIPPPSGRPLPEETGMESLGSPAEDEHTSSPPHTLNFNGAHRKRKTLVAPEINISLDQSEGSILSDDFLDTPDDLDINVDDIETPDETDSLEFLGNGNELEWEDDTPVATAKNMPGDSADLFGDGGTEHRIDLQMIKPYMRVVTHGGYYGEGLNAIIVFAACYLPDSNLADYHYIMENLFLYVISSLELLVAEDYMIVYLNGATPRRRMPGLGWLKKCYQMIDRRLRKNLKALIIVHPSWFIRTVLAISRPFISVKFINKIQYVHSLEELEQLIPMEHVQIPDCVSQYEEERIKARRERAEEKQDMAERESRPVPPAEDQETSMP", "length": 411, "header": "tr|A0A8V1AFZ8-1|A0A8V1A5R1_CHICK Computationally mapped isoform of ATCAY kinesin light chain interacting caytaxin OS=Gallus gallus OX=9031 GN=ATCAY PE=4 SV=1 CANONICAL=A0A8V1A5R1-1" }, "locus": { "chromosome": "28", "start_pos": 1915579, "end_pos": 1908256, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067443.1", "url": "https://www.ensembl.org/id/ENSGALT00010067443.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041232.1", "url": "https://www.ensembl.org/id/ENSGALP00010041232.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:420094", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420094", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A5R1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5R1" } ], "pmid": "" }, { "name": "mitochondrial membrane", "id": "GO:0031966", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031966", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A5R1", 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This record is derived from a genomic sequence (NC_052581.1) annotated using gene prediction method: Gnomon. 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CANONICAL=A0A8V1A5S6-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A5S6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5S6/entry#A0A8V1A5S6-1", "sequence": { "sequence": "MIQTVWVSSSRSRASRRPDGQRTSWKCGFIRTIIQHICLRHHFKAQGKTRMLKKIQICLCFFFVSGILYEISLLSGCFFSCMPMPKQFLTPEQVLNLGRSIIFLETTERLEPPPLVSCSVESAARIYQDRPIILFMKGLTNDTVLDSNSSYTAFSLLSSMKNVFLFPLQMENVFQETPLLQWYNEVDPEEEKNWVHVSSDASRLALIWKYGGIYMDTDVISIRPIPEGSFLAAQKSRFSSNGIFGFPAHHKFIWDCMENFVLKYNGNIWGNQGPFLMTRMLKAICNLTDFEGVEDHSCQNISFLNPQRFYPIPYPAWSRYYDVWDKVPDFNHSYALHLWNFMNRNRKAVVAGSNSLAEKLYKTYCPSTYEDLIQNAELRVFTSYEDSV", "length": 388, "header": "tr|A0A8V1A5S6-1|A0A8V1A5S6_CHICK Isoform 1 of Alpha-1,4-N-acetylglucosaminyltransferase OS=Gallus gallus OX=9031 GN=A4GNT PE=3 SV=1 CANONICAL=A0A8V1A5S6-1" }, "locus": { "chromosome": "9", "start_pos": 3770269, "end_pos": 3767161, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010059915.1", "url": "https://www.ensembl.org/id/ENSGALT00010059915.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036675.1", "url": "https://www.ensembl.org/id/ENSGALP00010036675.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:429136", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:429136", "resource": "KEGG Pathway" }, { "id": "R-GGA-913709", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-913709", "resource": "Reactome", "description": "O-linked glycosylation of mucins" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZG90-1", "protein_name": "Alpha-1,4-N-acetylglucosaminyltransferase", "gene_name": "A4gnt", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLKELHLSLSLVLVFACGLLYQLTLRSQCFFACLPPFTSPQGLEGLLRNGRSIVFIETSERLEPPPLVSCAVESAAKIYQEQPILFFMKGLSNATQMTSNTSSYPAFSLLSAINNVFFVPLDMKTLFEDTPLFSWYTKVNSSREKHWLHVSSDASRLAIIWKYGGVYMDTDVISIRPIPEENFLAAQGSQHSSNGVFGFLPHHPFLWACMENFVEHYNSGIWGNQGPKLMTRMLKIWCRLKDFQGLGDLKCLNISFLHPQRFYPIPYPEWRRYYQVWDRDLSFNDSYALHLWNFMNREGKTVVRGSNSLVENLYQKHCPKTYRVLIQGAEGTVSRKSGKGNR", "length": 342 }, "evidence": [ { "id": "A0A8V1A5S6", "url": "https://omabrowser.org/oma/group/A0A8V1A5S6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "I3LSM2-1", "protein_name": "Alpha-1,4-N-acetylglucosaminyltransferase", "gene_name": "A4GNT", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLMKLQLSLLIVLLACGFLYQFTLKSSCLFPFLLPYKSQQGLEALLGHGRSIVFLETSERTEPSPLVSCAVESAAKVYPEQPVLLLLKGLTNSTQLLSNSTSPALSLLSAIDNVFLFPLDMKSLFEDTPLFSWYTRINSSAERNWLYVSSDASRLAIIWKYGGVYMDSDVISIRPIPEENFLAAQESQFSSNGVFGFLPHHPFLWQCMENFVENYNSDIWGHQGPYLMTRILRVWCKLRDFQEVSDLRCMNLSFLHPQRFYPISYPAWKRYYEVWDTEPSFNDSYALHLWNHMNREGRAVIRGSNTLVENLYRKYCPRTYRDLLQGPEESVTWEWDPGNK", "length": 340 }, "evidence": [ { "id": "A0A8V1A5S6", "url": "https://omabrowser.org/oma/group/A0A8V1A5S6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q14BT6-1", "protein_name": "Alpha-1,4-N-acetylglucosaminyltransferase", "gene_name": "A4gnt", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLKEIYLSLSLVLVFACGLLYQLTMRSQCFFACLPPFSFPQGLDGLLRSGRSIMFIETSERVEPPPMVSCAVESAAKIYPEQPIIFFMKGLRDSVQLTSNTSYPAFSLLSAINNVFFVPLDMERLFKDTPLFSWYTKVNSSTEKHWLHVSSDAARLAIIWKYGGIYMDTDVISLQPIPEENFLAAQGSRHSSNGVFGFLPHHPFLWACMENFVEHYDSTIWGNQGPQLMTRMLRVWCRLKDFHGLGDLKCLNISFLHPQRFYPIPYPQWKRYYQVWDKEPSFNESYALHLWNYMNKEGKTVVRGSKTLVENLYQKHCPKTYRVLIQGAEGTVSKKPGTGSR", "length": 341 }, "evidence": [ { "id": "A0A8V1A5S6", "url": "https://omabrowser.org/oma/group/A0A8V1A5S6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9UNA3-1", "protein_name": "Alpha-1,4-N-acetylglucosaminyltransferase", "gene_name": "A4GNT", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRKELQLSLSVTLLLVCGFLYQFTLKSSCLFCLPSFKSHQGLEALLSHRRGIVFLETSERMEPPHLVSCSVESAAKIYPEWPVVFFMKGLTDSTPMPSNSTYPAFSFLSAIDNVFLFPLDMKRLLEDTPLFSWYNQINASAERNWLHISSDASRLAIIWKYGGIYMDTDVISIRPIPEENFLAAQASRYSSNGIFGFLPHHPFLWECMENFVEHYNSAIWGNQGPELMTRMLRVWCKLEDFQEVSDLRCLNISFLHPQRFYPISYREWRRYYEVWDTEPSFNVSYALHLWNHMNQEGRAVIRGSNTLVENLYRKHCPRTYRDLIKGPEGSVTGELGPGNK", "length": 340 }, "evidence": [ { "id": "A0A8V1A5S6", "url": "https://omabrowser.org/oma/group/A0A8V1A5S6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A5S6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5S6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "protein O-linked glycosylation", "id": "GO:0006493", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006493", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A5S6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5S6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "acetylglucosaminyltransferase activity", "id": "GO:0008375", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008375", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A5S6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5S6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 141, "end_pos": 143, "annotation": "n_glycosylation_sequon" }, { "start_pos": 148, "end_pos": 150, "annotation": "n_glycosylation_sequon" }, { "start_pos": 286, "end_pos": 288, "annotation": "n_glycosylation_sequon" }, { "start_pos": 300, "end_pos": 302, "annotation": "n_glycosylation_sequon" }, { "start_pos": 331, "end_pos": 333, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1A5S6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5S6" }, { "id": "PF04572", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04572" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Alpha 1,4-glycosyltransferase", "eco_id": "ECO_0000259", "start_pos": 246, "end_pos": 370, "start_aa": "Phe", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 141, "end_pos": 143 }, { "start_pos": 148, "end_pos": 150 }, { "start_pos": 286, "end_pos": 288 }, { "start_pos": 300, "end_pos": 302 }, { "start_pos": 331, "end_pos": 333 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A5S9-1", "uniprot_ac": "A0A8V1A5S9", "uniprot_id": "A0A8V1A5S9_CHICK", "mass": { "chemical_mass": 54616.0, "monoisotopic_mass": 54616.0 }, "refseq": { "ac": "XP_040506745", "name": "protein FAM217B isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040506745" }, "gene_names": [ { "name": "FAM217B", "type": "recommended", "evidence": [ { "id": "A0A8V1A5S9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5S9" } ] }, { "name": "FAM217B", "type": "synonym", "evidence": [ { "id": "XP_040506745", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040506745" } ] } ], "protein_names": [ { "name": "Family with sequence similarity 217 member B", "type": "synonym", "evidence": [ { "id": "A0A8V1A5S9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5S9/entry#names_and_taxonomy" } ] }, { "name": "protein FAM217B isoform X2", "type": "synonym", "evidence": [ { "id": "XP_040506745", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040506745" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052551.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040506745", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040506745" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A5S9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5S9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FAM217B", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5S9", "locus": { "chromosome": "20", "start_pos": 7221379, "end_pos": 7213052, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010024565", "url": "https://www.ensembl.org/id/ENSGALG00010024565" } ] } } ], "crossref": [ { "id": "A0A8V1A5S9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A5S9", "database": "AlphaFoldDB", "categories": [] }, { "id": "419221", "url": "https://www.ncbi.nlm.nih.gov/gene/419221", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR029266", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029266", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A5S9", "url": "https://www.orthodb.org/?gene=A0A8V1A5S9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22145", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22145", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22145:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22145:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15344", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15344", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040506745", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040506745", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1A5S9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5S9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A5S9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5S9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGPGIQEHPLLLHQKAQKKESQINENHKGTVNNGKSHPSTKGVKKSVSHVKSPGRLCKNVPTTNEKTSCDAQDDNQPSVLKKGRNQPDDSTQSKQITSVCTSLPRVQGSKRSLPETRQSESLLHRIPPATKGSTQGSFCRVKDVPVQHFYCSKKEQLEKNHEEHVAEAGPCSSKWQEASVNEMFLDFESVQIIKEDAEDDSASDLSDSERIPIPPSPCTPPELILRAEEIDPLCLERVPDTGFKESEYYYPDFLPPPFNSWDLKQLAIFVNVEGRSELRPKPTGFLEKYIDRLLQLEWLQMQTVQNEKAKAAKARPQTAPSSIRTLKSPGKCKALLSPSPNKQMVPQESVTKLPTCYSGHRVDPYCEESRQFYSHPGHLKLSERTGHATSSQRQPGEVRNELKKTTAKQQLLNMQPSENSSKIQSVGNIRPPKQAPAFHGSAAPIKGIKTYACTNTKKNGNANNYVPSKKPAGDRKIKTNGTKQTSRKFK", "length": 490, "header": "tr|A0A8V1A5S9-1|A0A8V1A5S9_CHICK Isoform 1 of Family with sequence similarity 217 member B OS=Gallus gallus OX=9031 GN=FAM217B PE=4 SV=1 CANONICAL=A0A8V1A5S9-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A5S9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5S9/entry#A0A8V1A5S9-1", "sequence": { "sequence": "MGPGIQEHPLLLHQKAQKKESQINENHKGTVNNGKSHPSTKGVKKSVSHVKSPGRLCKNVPTTNEKTSCDAQDDNQPSVLKKGRNQPDDSTQSKQITSVCTSLPRVQGSKRSLPETRQSESLLHRIPPATKGSTQGSFCRVKDVPVQHFYCSKKEQLEKNHEEHVAEAGPCSSKWQEASVNEMFLDFESVQIIKEDAEDDSASDLSDSERIPIPPSPCTPPELILRAEEIDPLCLERVPDTGFKESEYYYPDFLPPPFNSWDLKQLAIFVNVEGRSELRPKPTGFLEKYIDRLLQLEWLQMQTVQNEKAKAAKARPQTAPSSIRTLKSPGKCKALLSPSPNKQMVPQESVTKLPTCYSGHRVDPYCEESRQFYSHPGHLKLSERTGHATSSQRQPGEVRNELKKTTAKQQLLNMQPSENSSKIQSVGNIRPPKQAPAFHGSAAPIKGIKTYACTNTKKNGNANNYVPSKKPAGDRKIKTNGTKQTSRKFK", "length": 490, "header": "tr|A0A8V1A5S9-1|A0A8V1A5S9_CHICK Isoform 1 of Family with sequence similarity 217 member B OS=Gallus gallus OX=9031 GN=FAM217B PE=4 SV=1 CANONICAL=A0A8V1A5S9-1" }, "locus": { "chromosome": "20", "start_pos": 7216914, "end_pos": 7214287, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010059920.1", "url": "https://www.ensembl.org/id/ENSGALT00010059920.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036680.1", "url": "https://www.ensembl.org/id/ENSGALP00010036680.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A5S9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5S9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 419, "end_pos": 421, "annotation": "n_glycosylation_sequon" }, { "start_pos": 480, "end_pos": 482, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], 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} ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A5T2-1", "uniprot_ac": "A0A8V1A5T2", "uniprot_id": "A0A8V1A5T2_CHICK", "mass": { "chemical_mass": 64542.0, "monoisotopic_mass": 64542.0 }, "refseq": {}, "gene_names": [ { "name": "IPP", "type": "recommended", "evidence": [ { "id": "A0A8V1A5T2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5T2" } ] } ], "protein_names": [ { "name": "Actin-binding protein IPP", "type": 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"evidence": [ { "database": "UniProtKB", "id": "A0A8V1A5T2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5T2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "IPP", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5T2", "locus": { "chromosome": "8", "start_pos": 20914027, "end_pos": 20921412, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010026335", "url": "https://www.ensembl.org/id/ENSGALG00010026335" } ] } } ], "crossref": [ { "id": "A0A8V1A5T2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A5T2", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd18256", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18256", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18466", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18466", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006652", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006652", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011705", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011705", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015915", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015915", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017096", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017096", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030104", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030104", "database": "InterPro", "categories": [ 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"Ensembl Peptide", "id": "ENSGALP00010039433.1", "url": "https://www.ensembl.org/id/ENSGALP00010039433.1" } ] } }, { "isoform_ac": "A0A8V1AD60-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5T2/entry#A0A8V1AD60-1", "sequence": { "sequence": "MACAAVGSAGGSSFSDRHARLLLAQINRLRVGQSFCDVRLEVGSEAFSVHRLVLAASSPYFAALFAGGMKESGRDVVRIAGVEAGIFHTLLDFIYTGVVSISEHNVQELIVAADMLQLSEVVELCCEFLKGQIDPLNCIGFFQFSEQIACHDLLEFTESYIHAHFLEVQAGEEFLALSKEQLVKILRSEDLSIEDEYQVFLAAMQWILKDLGRRRKYVVEVLEPVRFPLLPAQRLLKYIEGERRKRSDRCLYSNKLFLTTSLLICSFPQGIPDFSLRVALQTLLKEYCEVCKSPKENKVSSFLQASKGRPRRKARKYLYAVGGYTRLQGGRWSDSRALSCVERFDTFSHYWTTVSSLHQARSGLGVAVVGGMVYAIGGEKDSMIFDCTECYDPVSKQWTIVASMNHPRCGLGVCTCYGAIYALGGWVGAEIGNTIERFDPEENSWDVVGSMAVPRYYFGCCEIQGLIYVVGGISHEGVELRSVEVYDPISKRWSELPPMGTRRAYLGVAALNDCIYAVGGWNESQDALATVERYSFEEEKWVEVAPMKMPRAGVCVVTVNGFLYASGGRAPSHDFAAPVTSDSVEVYNPHMDSWTEIANMITSRCEGGVAVL", "length": 612, "header": "tr|A0A8V1AD60-1|A0A8V1AD60_CHICK Computationally mapped isoform of Actin-binding protein IPP OS=Gallus gallus OX=9031 GN=IPP PE=4 SV=1 CANONICAL=A0A8V1A5T2-1" }, "locus": { "chromosome": "8", "start_pos": 20921346, "end_pos": 20915547, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010064090.1", "url": "https://www.ensembl.org/id/ENSGALT00010064090.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039432.1", "url": "https://www.ensembl.org/id/ENSGALP00010039432.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A5T2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5T2" } ], "pmid": "" }, { "name": "ubiquitin-like ligase-substrate adaptor activity", "id": "GO:1990756", "url": 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"url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06257", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001623", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001623", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032843", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032843", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036869", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036869", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052317", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052317", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A5T7", "url": "https://www.orthodb.org/?gene=A0A8V1A5T7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A8D6", "url": "https://www.orthodb.org/?gene=A0A8V1A8D6", "database": "OrthoDB", "categories": [ "Protein 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"https://www.uniprot.org/uniprotkb/A0A8V1A8D6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A8D6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8D6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAQPPPEATGGGGGGRERSARSPPRSAAWNGDCGPEPPFAPEDDGNEEGDGDGASAPDGPGPCGCRGERAAPRAPPPRDGSCALGCRRRTEPGPEEGDEDPGKGTRRPRRRQRPRSAPKEKEEGGRGQRGGGARLKALLEAALSSWLSAGTGGAAPGGVRGWTRRVGLRAARGLRAGGELTLRLLWMLCALLLLLVVLLLGVLRLCWRASAAGVAALGRTRLAELLDAAVLRRTRGFLGEDGTWRRLWARWRRWRSAPEEPQAGCGMGDAVPGSDGGAPGSSAEEVSRLLAMAEVPEEELNPFQALGVEVTASDAELRKAYRRLAVLVRGGCVSLTASPGCSAESFCAFQVHPDKSEHPRAEEAFKVLRAAWDIVSSPERRKEYEM", "length": 386, "header": "tr|A0A8V1A5T7-1|A0A8V1A5T7_CHICK Isoform 1 of DnaJ heat shock protein family (Hsp40) member C14 OS=Gallus gallus OX=9031 GN=DNAJC14 PE=4 SV=1 CANONICAL=A0A8V1A5T7-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A5T7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5T7/entry#A0A8V1A5T7-1", "sequence": { "sequence": "MAQPPPEATGGGGGGRERSARSPPRSAAWNGDCGPEPPFAPEDDGNEEGDGDGASAPDGPGPCGCRGERAAPRAPPPRDGSCALGCRRRTEPGPEEGDEDPGKGTRRPRRRQRPRSAPKEKEEGGRGQRGGGARLKALLEAALSSWLSAGTGGAAPGGVRGWTRRVGLRAARGLRAGGELTLRLLWMLCALLLLLVVLLLGVLRLCWRASAAGVAALGRTRLAELLDAAVLRRTRGFLGEDGTWRRLWARWRRWRSAPEEPQAGCGMGDAVPGSDGGAPGSSAEEVSRLLAMAEVPEEELNPFQALGVEVTASDAELRKAYRRLAVLVRGGCVSLTASPGCSAESFCAFQVHPDKSEHPRAEEAFKVLRAAWDIVSSPERRKEYEM", "length": 386, "header": "tr|A0A8V1A5T7-1|A0A8V1A5T7_CHICK Isoform 1 of DnaJ heat shock protein family (Hsp40) member C14 OS=Gallus gallus OX=9031 GN=DNAJC14 PE=4 SV=1 CANONICAL=A0A8V1A5T7-1" }, "locus": { "chromosome": "34", "start_pos": 1762626, "end_pos": 1762575, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010062393.1", "url": "https://www.ensembl.org/id/ENSGALT00010062393.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038572.1", "url": "https://www.ensembl.org/id/ENSGALP00010038572.1" } ] } }, { "isoform_ac": "A0A8V1A8D6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5T7/entry#A0A8V1A8D6-1", "sequence": { "sequence": "MGDAVPGSDGGAPGSSAEEVSRLLAMAEVPEEELNPFQALGVEVTASDAELRKAYRRLAVLVHPDKSEHPRAEEAFKVLRAAWDIVSSPERRKEYEIKRMAESELSRSVNEFLSRLQDDLKEAMNTMMCSKCQGKHRRFEMDRDPLSARYCAECSQLHPAEEGDLWAESSLLGLKITYFAMMDGKVYDITEWAGCQRVGICPDTHRVPYHISFGVRSAGAGGRQRSTSKGSPSSAADLQDFFTRMFQGTSGQVPGGFPPPPAPTAPQGATAGTTRAEGAVPKSDTKHKRRKKVRRPFQR", "length": 299, "header": "tr|A0A8V1A8D6-1|A0A8V1A8D6_CHICK Computationally mapped isoform of DnaJ heat shock protein family (Hsp40) member C14 OS=Gallus gallus OX=9031 GN=DNAJC14 PE=4 SV=1 CANONICAL=A0A8V1A5T7-1" }, "locus": { "chromosome": "34", "start_pos": 1762972, "end_pos": 1761571, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010062392.1", "url": "https://www.ensembl.org/id/ENSGALT00010062392.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038571.1", "url": "https://www.ensembl.org/id/ENSGALP00010038571.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1A5T7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5T7" }, { "id": "PS50076", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50076" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "J", "eco_id": "ECO_0000259", "start_pos": 301, "end_pos": 386, "start_aa": "Asn", "end_aa": "Met", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A5V8-1", "uniprot_ac": "A0A8V1A5V8", "uniprot_id": "A0A8V1A5V8_CHICK", "mass": { "chemical_mass": 123735.0, "monoisotopic_mass": 123735.0 }, "refseq": { "ac": "XP_040537923", "name": "voltage-dependent calcium channel subunit alpha-2/delta-3 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040537923" }, "gene_names": [ { "name": "CACNA2D3", "type": "recommended", "evidence": [ { "id": "A0A8V1A5V8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5V8" } ] }, { "name": "CACNA2D3", "type": "synonym", "evidence": [ { "id": "XP_040537923", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040537923" } ] } ], "protein_names": [ { "name": "Calcium voltage-gated channel auxiliary subunit alpha2delta 3", "type": "synonym", "evidence": [ { "id": "A0A8V1A5V8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5V8/entry#names_and_taxonomy" } ] }, { "name": "voltage-dependent calcium channel subunit alpha-2/delta-3 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_040537923", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040537923" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052584.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040537923", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040537923" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A5V8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5V8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CACNA2D3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5V8", "locus": { "chromosome": "12", "start_pos": 7913294, "end_pos": 7502267, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027868", "url": "https://www.ensembl.org/id/ENSGALG00010027868" } ] } } ], "crossref": [ { "id": "A0A8V1A5V8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A5V8", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd01463", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01463", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12912", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12912", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "415996", "url": "https://www.ncbi.nlm.nih.gov/gene/415996", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002035", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002035", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013608", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013608", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036465", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036465", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051173", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051173", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:415996", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415996", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KEPLLQX", "url": "https://omabrowser.org/oma/group/KEPLLQX/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A5V8", "url": "https://www.orthodb.org/?gene=A0A8V1A5V8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AAR2", "url": "https://www.orthodb.org/?gene=A0A8V1AAR2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AHY9", "url": "https://www.orthodb.org/?gene=A0A8V1AHY9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10166", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10166", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10166:SF25", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10166:SF25", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08399", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08399", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08473", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08473", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13768", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13768", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-112308", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-112308", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_040537923", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040537923", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1A5V8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5V8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A5V8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5V8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AAR2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAR2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AAR2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAR2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHY9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHY9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHY9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHY9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLENLNLLRASGVFFFIFWTAFNTALVDVVGSEQQIPLSVVKLWASAFGGEIKSIAAKYSGSQLLQKKYKEYEKDVAIEEIDGLQLVKKLAKNMEEMFHKKSEAVRRLVEAAEDAYLKHEFDADLQYEYFNAVLINERDEEGNYLELGKEFILVPNDHFNNLPVNISLSDVQVPTNMYNKDPAIVNGVYWSESLNKVFVDNFDRDPSLIWQYFGSAKGFFRQYPGIKWEPDENGVIAFDCRNRKWYIQAATSPKDVVILVDVSGSMKGLRLTIAKQTVSSILDTLGDDDFFNIIAYNEELHYVEPCLNGTLVQADRTNKEHFREHLDKLFAKGIGMLDIALNEAFNMLNEFNHTGQGSICSQAIMLITDGAVDTYDTIFAKYNWPDRKVRIFTYLIGREAAFADNLKWMACANKGFFTQISTLADVQENVMEYLHVLSRPKVIDQEHDVVWTEAYIDSTLPQAQKLADDQGLVLMTTVAMPVFSKQNETRSKGILLGVVGTDVPVKELLKAIPKYKLGIHGYAFAITNNGYILTHPELRPLYEEGKKRRKPNYSSVDLSEVEWEDRDDVLRNAMVNRKTGKFSMEVKKTVDKGKRVLVMTNDYYYTDIKGTPFSLGVALSRGHGKYFFRGNVTVEEGLHDLEHPDVSLADEWSYCNTDLHPEHRQMTQLEAIKRYLTGKEPLLQCDKELIQEVLFDAVVSAPIEAYWTSLALNKSENSDKGVEVAFLGTRTGLSRINLFVGPEQLTNQDFLTAEDKENIFNADHFPLWYRRAAEQIPGSFVYSIPFSTETANKSNVVTASTAIQLLDDRKSPVVAAVGIQMKLEFFQRKFWTASRQCASLDGRCAISCDDEAINCYLIDNNGFILVSEDYGQTGNFFGEVEGAVMNKLLTMGSFKRITLYDYQAMCRTNKESSDSAHSLLDPYNAFFAAVKWIMTELVLFLVEFNLCSWWHSDLTAKAQRLKQTLEPCDTEYPAFVSERTIKETTGNIACDDCFKSFVIQQIPSSNLFMVVVDNECFCDSVPPITMAPIEIRYNESLKCERLKSQKIRRRPESCHGFHPEENARECGGVPGLSAKPPFVLLPLILTIFSR", "length": 1090, "header": "tr|A0A8V1A5V8-1|A0A8V1A5V8_CHICK Isoform 1 of Calcium voltage-gated channel auxiliary subunit alpha2delta 3 OS=Gallus gallus OX=9031 GN=CACNA2D3 PE=3 SV=1 CANONICAL=A0A8V1A5V8-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A5V8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5V8/entry#A0A8V1A5V8-1", "sequence": { "sequence": "MLENLNLLRASGVFFFIFWTAFNTALVDVVGSEQQIPLSVVKLWASAFGGEIKSIAAKYSGSQLLQKKYKEYEKDVAIEEIDGLQLVKKLAKNMEEMFHKKSEAVRRLVEAAEDAYLKHEFDADLQYEYFNAVLINERDEEGNYLELGKEFILVPNDHFNNLPVNISLSDVQVPTNMYNKDPAIVNGVYWSESLNKVFVDNFDRDPSLIWQYFGSAKGFFRQYPGIKWEPDENGVIAFDCRNRKWYIQAATSPKDVVILVDVSGSMKGLRLTIAKQTVSSILDTLGDDDFFNIIAYNEELHYVEPCLNGTLVQADRTNKEHFREHLDKLFAKGIGMLDIALNEAFNMLNEFNHTGQGSICSQAIMLITDGAVDTYDTIFAKYNWPDRKVRIFTYLIGREAAFADNLKWMACANKGFFTQISTLADVQENVMEYLHVLSRPKVIDQEHDVVWTEAYIDSTLPQAQKLADDQGLVLMTTVAMPVFSKQNETRSKGILLGVVGTDVPVKELLKAIPKYKLGIHGYAFAITNNGYILTHPELRPLYEEGKKRRKPNYSSVDLSEVEWEDRDDVLRNAMVNRKTGKFSMEVKKTVDKGKRVLVMTNDYYYTDIKGTPFSLGVALSRGHGKYFFRGNVTVEEGLHDLEHPDVSLADEWSYCNTDLHPEHRQMTQLEAIKRYLTGKEPLLQCDKELIQEVLFDAVVSAPIEAYWTSLALNKSENSDKGVEVAFLGTRTGLSRINLFVGPEQLTNQDFLTAEDKENIFNADHFPLWYRRAAEQIPGSFVYSIPFSTETANKSNVVTASTAIQLLDDRKSPVVAAVGIQMKLEFFQRKFWTASRQCASLDGRCAISCDDEAINCYLIDNNGFILVSEDYGQTGNFFGEVEGAVMNKLLTMGSFKRITLYDYQAMCRTNKESSDSAHSLLDPYNAFFAAVKWIMTELVLFLVEFNLCSWWHSDLTAKAQRLKQTLEPCDTEYPAFVSERTIKETTGNIACDDCFKSFVIQQIPSSNLFMVVVDNECFCDSVPPITMAPIEIRYNESLKCERLKSQKIRRRPESCHGFHPEENARECGGVPGLSAKPPFVLLPLILTIFSR", "length": 1090, "header": "tr|A0A8V1A5V8-1|A0A8V1A5V8_CHICK Isoform 1 of Calcium voltage-gated channel auxiliary subunit alpha2delta 3 OS=Gallus gallus OX=9031 GN=CACNA2D3 PE=3 SV=1 CANONICAL=A0A8V1A5V8-1" }, "locus": { "chromosome": "12", "start_pos": 7912060, "end_pos": 7503153, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067544.1", "url": "https://www.ensembl.org/id/ENSGALT00010067544.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041287.1", "url": "https://www.ensembl.org/id/ENSGALP00010041287.1" } ] } }, { "isoform_ac": "A0A8V1AAR2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5V8/entry#A0A8V1AAR2-1", "sequence": { "sequence": "MAPYNAFFAAVKWIMTELVLFLVEFNLCSWWHSDLTAKAQRLKQTLEPCDTEYPAFVSERTIKETTGNIACDDCFKSFVIQQIPSSNLFMVVVDNECFCDSVPPITMAPIEIRYNESLKCERLKSQKIRRRPESCHGFHPEENARECGGVPGLSAKPPFVLLPLILTIFSR", "length": 171, "header": "tr|A0A8V1AAR2-1|A0A8V1AAR2_CHICK Computationally mapped isoform of Calcium voltage-gated channel auxiliary subunit alpha2delta 3 OS=Gallus gallus OX=9031 GN=CACNA2D3 PE=4 SV=1 CANONICAL=A0A8V1A5V8-1" }, "locus": { "chromosome": "12", "start_pos": 7912060, "end_pos": 7888084, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067536.1", "url": "https://www.ensembl.org/id/ENSGALT00010067536.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041279.1", "url": "https://www.ensembl.org/id/ENSGALP00010041279.1" } ] } }, { "isoform_ac": "A0A8V1AHY9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5V8/entry#A0A8V1AHY9-1", "sequence": { "sequence": "MLENLNLLRASGVFFFIFWTAFNTALVDVVGSEQQIPLSVVKLWASAFGGEIKSIAAKYSGSQLLQKKYKEYEKDVAIEEIDGLQLVKKLAKNMEEMFHKKSEAVRRLVEAAEDAYLKHEFDADLQYEYFNAVLINERDEEGNYLELGKEFILVPNDHFNNLPVNISLSDVQVPTNMYNKDPAIVNGVYWSESLNKVFVDNFDRDPSLIWQYFGSAKGFFRQYPGIKWEPDENGVIAFDCRNRKWYIQAATSPKDVVILVDVSGSMKGLRLTIAKQTVSSILDTLGDDDFFNIIAYNEELHYVEPCLNGTLVQADRTNKEHFREHLDKLFAKGIGMLDIALNEAFNMLNEFNHTGQGSICSQAIMLITDGAVDTYDTIFAKYNWPDRKVRIFTYLIGREAAFADNLKWMACANKGFFTQISTLADVQENVMEYLHVLSRPKVIDQEHDVVWTEAYIDSTLADDQGLVLMTTVAMPVFSKQNETRSKGILLGVVGTDVPVKELLKAIPKYKLGIHGYAFAITNNGYILTHPELRPLYEEGKKRRKPNYSSVDLSEVEWEDRDDVLRNAMVNRKTGKFSMEVKKTVDKGKRVLVMTNDYYYTDIKGTPFSLGVALSRGHGKYFFRGNVTVEEGLHDLEHPDVSLADEWSYCNTDLHPEHRQMTQLEAIKRYLTGKEPLLQCDKELIQEVLFDAVVSAPIEAYWTSLALNKSENSDKGVEVAFLGTRTGLSRINLFVGPEQLTNQDFLTAEDKENIFNADHFPLWYRRAAEQIPGSFVYSIPFSTETANKSNVVTASTAIQLLDDRKSPVVAAVGIQMKLEFFQRKFWTASRQCASLDGRCAISCDDEAINCYLIDNNGFILVSEDYGQTGNFFGEVEGAVMNKLLTMGSFKRITLYDYQAMCRTNKESSDSAHSLLDPYNAFFAAVKWIMTELVLFLVEFNLCSWWHSDLTAKAQRLKQTLEPCDTEYPAFVSERTIKETTGNIACDDCFKSFVIQQIPSSNLFMVVVDNECFCDSVPPITMAPIEIRYNESLKCERLKSQKIRRRPESCHGFHPEENARECGGVPGLSAKPPFVLLPLILTIFSR", "length": 1084, "header": "tr|A0A8V1AHY9-1|A0A8V1A5V8_CHICK Computationally mapped isoform of Calcium voltage-gated channel auxiliary subunit alpha2delta 3 OS=Gallus gallus OX=9031 GN=CACNA2D3 PE=3 SV=1 CANONICAL=A0A8V1A5V8-1" }, "locus": { "chromosome": "12", "start_pos": 7912060, "end_pos": 7503153, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067540.1", "url": "https://www.ensembl.org/id/ENSGALT00010067540.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041283.1", "url": "https://www.ensembl.org/id/ENSGALP00010041283.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:415996", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415996", "resource": "KEGG Pathway" }, { "id": "R-GGA-112308", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-112308", "resource": "Reactome", "description": "Presynaptic depolarization and calcium channel opening" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1MA75-1", "protein_name": "Calcium voltage-gated channel auxiliary subunit alpha2delta 3", "gene_name": "CACNA2D3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAGLGWQRRASRGPWALLTAALLYAALGDVVRSEQQIPLSVVKLWASAFGGEIKSIAAKYSGSQLLQKKYKEYEKDVAIEEIDGLQLVKKLAKNMEEMFHKKSEAVRRLVEAAEEAHLKHEFDADLQYEYFNAVLINERDKDGNFLELGKEFILAPNDHFNNLPVNISLSDVQVPTNMYNKDPAIVNGVYWSESLNKVFVDNFDRDPSLIWQYFGSAKGFFRQYPGIKWEPDENGVIAFDCRNRKWYIQAATSPKDVVILVDVSGSMKGLRMTIAKQTVSSILDTLGDDDFFNIIAYNEELHYVEPCLNGTLVQADRTNKEHFREHLDKLFAKGIGMLDIALNEAFNILSDFNHTGQGSICSQAIMLITDGAVDTYDTIFAKYNWPDRKVRIFTYLIGREAAFADNLKWMACANKGFFTQISTLADVQENVMEYLHVLSRPKVIDQEHDVVWTEAYIDSTLPQAQKLADDQGPVLMTTVAMPVFSKQNETRSKGILLGVVGTDVPVKELLKTIPKYKLGIHGYAFAITNNGYILTHPELRPLYEEGKKRRKPNYSSVDLSEVEWEDRDDVLRNAMVNRKTGKFSMEVKKTVDKGKRVLVMTNDYYYTDIKGTPFSLGVALSRGHGKYFFRGNVTIEEGLHDLEHPDVSLADEWSYCNTDLHPEHRHLSQLEAIKLYLKGKEPLLQCDKELIQEVLFDAVVSAPIEAYWTSLALNKSENSDKGVEVAFLGTRTGLSRINLFVGAEQLTNQDFLKAGDKENIFNADHFPLWYRRAAEQIPGSFVYSIPFSTGTVNKSNVVTASTSIQLLDERKSPVVAAVGIQMKLEFFQRKFWTASRQCASLDGKCSISCDDETVNCYLIDNNGFILVSEDYTQTGDFFGEVEGAVMNKLLTMGSFKRITLYDYQAMCRANKESSDGAHGLLDPYNAFLAAVKWIMTELVLFLVEFNLCSWWHSDMTAKAQKLKQTLEPCDTEYPAFVSERTIKETSGNIACEDCSKSFVIQQIPSSNLFMVVVDSSCLCESVAPITMAPIEIRYNESLKCERLKAQKIRRRPESCHGFHPEENARECGGAPNLKAKMVLILFPLLLMLFSR", "length": 1091 }, "evidence": [ { "id": "A0A8V1A5V8", "url": "https://omabrowser.org/oma/group/A0A8V1A5V8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8IZS8-1", "protein_name": "Voltage-dependent calcium channel subunit alpha-2/delta-3", "gene_name": "CACNA2D3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAGPGSPRRASRGASALLAAALLYAALGDVVRSEQQIPLSVVKLWASAFGGEIKSIAAKYSGSQLLQKKYKEYEKDVAIEEIDGLQLVKKLAKNMEEMFHKKSEAVRRLVEAAEEAHLKHEFDADLQYEYFNAVLINERDKDGNFLELGKEFILAPNDHFNNLPVNISLSDVQVPTNMYNKDPAIVNGVYWSESLNKVFVDNFDRDPSLIWQYFGSAKGFFRQYPGIKWEPDENGVIAFDCRNRKWYIQAATSPKDVVILVDVSGSMKGLRLTIAKQTVSSILDTLGDDDFFNIIAYNEELHYVEPCLNGTLVQADRTNKEHFREHLDKLFAKGIGMLDIALNEAFNILSDFNHTGQGSICSQAIMLITDGAVDTYDTIFAKYNWPDRKVRIFTYLIGREAAFADNLKWMACANKGFFTQISTLADVQENVMEYLHVLSRPKVIDQEHDVVWTEAYIDSTLPQAQKLTDDQGPVLMTTVAMPVFSKQNETRSKGILLGVVGTDVPVKELLKTIPKYKLGIHGYAFAITNNGYILTHPELRLLYEEGKKRRKPNYSSVDLSEVEWEDRDDVLRNAMVNRKTGKFSMEVKKTVDKGKRVLVMTNDYYYTDIKGTPFSLGVALSRGHGKYFFRGNVTIEEGLHDLEHPDVSLADEWSYCNTDLHPEHRHLSQLEAIKLYLKGKEPLLQCDKELIQEVLFDAVVSAPIEAYWTSLALNKSENSDKGVEVAFLGTRTGLSRINLFVGAEQLTNQDFLKAGDKENIFNADHFPLWYRRAAEQIPGSFVYSIPFSTGPVNKSNVVTASTSIQLLDERKSPVVAAVGIQMKLEFFQRKFWTASRQCASLDGKCSISCDDETVNCYLIDNNGFILVSEDYTQTGDFFGEIEGAVMNKLLTMGSFKRITLYDYQAMCRANKESSDGAHGLLDPYNAFLSAVKWIMTELVLFLVEFNLCSWWHSDMTAKAQKLKQTLEPCDTEYPAFVSERTIKETTGNIACEDCSKSFVIQQIPSSNLFMVVVDSSCLCESVAPITMAPIEIRYNESLKCERLKAQKIRRRPESCHGFHPEENARECGGAPSLQAQTVLLLLPLLLMLFSR", "length": 1091 }, "evidence": [ { "id": "A0A8V1A5V8", "url": "https://omabrowser.org/oma/group/A0A8V1A5V8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9Z1L5-1", "protein_name": "Voltage-dependent calcium channel subunit alpha-2/delta-3", "gene_name": "Cacna2d3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAGPGSLCCASRGASALLATALLYAALGDVVRSEQQIPLSVVKLWASAFGGEIKSIAAKYSGSQLLQKKYKEYEKDVAIEEIDGLQLVKKLAKIMEEMFHKKSEAVRRLVEAAEEAHLKHEFDADLQYEYFNAVLINERDKDGNFLELGKEFILAPNDHFNNLPVNISLSDVQVPTNMYNKDPAIVNGVYWSESLNKVFVDNFDRDPSLIWQYFGSAKGFFRQYPGIKWEPDENGVIAFDCRNRKWYIQAATSPKDVVILVDVSGSMKGLRLTIAKQTVSSILDTLGDDDFFNIITYNEELHYVEPCLNGTLVQADRTNKEHFREHLDKLFAKGIGMLDIALNEAFNILSDFNHTGQGSICSQAIMLITDGAVDTYDTIFAKYNWPDRKVRIFTYLIGREAAFADNLKWMACANKGFFTQISTLADVQENVMEYLHVLSRPKVIDQEHDVVWTEAYIDSTLPQAQKLADDQGLVLMTTVAMPVFSKQNETRSKGILLGVVGTDVPVKELLKTIPKYKLGIHGYAFAITNNGYILTHPELRPLYEEGKKRRKPNYSSVDLSEVEWEDRDDVLRNAMVNRKTGKFSMEVKKTVDKGKRVLVMTNDYYYTDIKGTPFSLGVALSRGHGKYFFRGNVTIEEGLHDLEHPDVSLADEWSYCNTDLHPEHRHLSQLEAIKLYLKGKEPLLQCDKELIQEVLFDAVVSAPIEAYWTSLALNKSENSDKGVEVAFLGTRTGLSRINLFVGAEQLTNQDFLKAGDKENIFNADHFPLWYRRAAEQIAGSFVYSIPFSTGTVNKSNVVTASTSIQLLDERKSPVVAAVGIQMKLEFFQRKFWTASRQCASLDGKCSISCDDETVNCYLIDNNGFILVSEDYTQTGDFFGEVEGAVMNKLLTMGSFKRITLYDYQAMCRANKESSDSAHGLLDPYKAFLSAAKWIMTELVLFLVEFNLCSWWHSDMTAKAQKLKQTLEPCDTEYPAFVSERTIKETTGNIACEDCSKSFVIQQIPSSNLFMVVVDSSCLCESVAPITMAPIEIRYNESLKCERLKAQKIRRRPESCHGFHPEENARECGGASSLQAQAALLLLPLVSSLFSR", "length": 1091 }, "evidence": [ { "id": "A0A8V1A5V8", "url": "https://omabrowser.org/oma/group/A0A8V1A5V8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "GABA-ergic synapse", "id": "GO:0098982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098982", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A5V8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5V8" } ], "pmid": "" }, { "name": "presynaptic active zone membrane", "id": "GO:0048787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048787", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A5V8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5V8" } ], "pmid": "" }, { "name": "voltage-gated calcium channel complex", "id": "GO:0005891", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005891", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A5V8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5V8" } ], "pmid": "" }, { "name": "monoatomic ion channel complex", "id": "GO:0034702", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034702", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A5V8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5V8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A5V8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5V8" } ], "pmid": "" }, { "name": "voltage-gated calcium channel activity", "id": "GO:0005245", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005245", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A5V8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5V8" } ], "pmid": "" }, { "name": "calcium channel activity", "id": "GO:0005262", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005262", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A5V8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5V8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of presynapse organization", "id": "GO:0099174", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099174", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A5V8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5V8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1034, "end_pos": 1036, "annotation": "n_glycosylation_sequon" }, { "start_pos": 165, "end_pos": 167, "annotation": "n_glycosylation_sequon" }, { "start_pos": 308, "end_pos": 310, "annotation": "n_glycosylation_sequon" }, { "start_pos": 352, "end_pos": 354, "annotation": "n_glycosylation_sequon" }, { "start_pos": 487, "end_pos": 489, "annotation": "n_glycosylation_sequon" }, { "start_pos": 552, "end_pos": 554, "annotation": "n_glycosylation_sequon" }, { "start_pos": 631, "end_pos": 633, "annotation": "n_glycosylation_sequon" }, { "start_pos": 713, "end_pos": 715, "annotation": "n_glycosylation_sequon" }, { "start_pos": 792, "end_pos": 794, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1A5V8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5V8" }, { "id": "PS50234", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50234" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "VWFA", "eco_id": "ECO_0000259", "start_pos": 255, "end_pos": 437, "start_aa": "Asp", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1034, "end_pos": 1036 }, { "start_pos": 165, "end_pos": 167 }, { "start_pos": 308, "end_pos": 310 }, { "start_pos": 352, "end_pos": 354 }, { "start_pos": 487, "end_pos": 489 }, { "start_pos": 552, "end_pos": 554 }, { "start_pos": 631, "end_pos": 633 }, { "start_pos": 713, "end_pos": 715 }, { "start_pos": 792, "end_pos": 794 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A5X0-1", "uniprot_ac": "A0A8V1A5X0", "uniprot_id": "A0A8V1A5X0_CHICK", "mass": { "chemical_mass": 63456.0, "monoisotopic_mass": 63456.0 }, "refseq": {}, "gene_names": [ { "name": "TCTN1", "type": "recommended", "evidence": [ { "id": "A0A8V1A5X0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5X0" } ] } ], "protein_names": [ { "name": "Tectonic family member 1", "type": "synonym", "evidence": [ { "id": "A0A8V1A5X0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5X0/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A5X0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5X0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TCTN1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5X0", "locus": { "chromosome": "15", "start_pos": 6006709, "end_pos": 5994367, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010025586", "url": "https://www.ensembl.org/id/ENSGALG00010025586" } ] } } ], "crossref": [ { "id": "A0A8V1A5X0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A5X0", "database": "AlphaFoldDB", "categories": [] }, { "id": "416870", "url": "https://www.ncbi.nlm.nih.gov/gene/416870", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040354", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040354", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057724", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057724", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416870", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416870", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "AGDVKIC", "url": "https://omabrowser.org/oma/group/AGDVKIC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A5X0", "url": "https://www.orthodb.org/?gene=A0A8V1A5X0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AB06", "url": "https://www.orthodb.org/?gene=A0A8V1AB06", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14611", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14611", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14611:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14611:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07773", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07773", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25752", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25752", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-5620912", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5620912", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1A5X0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5X0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A5X0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5X0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AB06", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB06", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AB06-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB06-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAALRLGLLLFLSPLRAAEPSTELPSSPEASSKTRATAWKRGRSGPAPLTDVAKLCVCDLLVAQCDVNCCCDPDCSAEDFSLFTTCSVPIVTGDSRLCSQKAAIYSLDTEANPPERVFKLVDHINPSVFCIHATNYEQALSFSSPETPTAENFDQLLKKYGGATFSAEPNSWSMNSDASDPSDANKSYRYEYGVPIQTVDAFLRLPSPVVSSWCSDANPAGFLVHQATKCIRSISVENCGNIQAVSMLFYINSSILAVPKSSQMVNITVQSVVVQSLNGMRTLLNSRDVLRHPMILDELCINIVLGVSYHITYTDTGEIIEAAASFVLGAVNKEALSVQQSFEISFTQVNTNPVPFSGNPGYVVGLAVRAGFKPQGYPFPIVILLSVLFLDQLHSDFLSWTPYIFHLFFTESKCVLFGYILEVTNVSVLTAISWNCSARITAAMNCQPLAQVLLDLLMGQSFPEYVAPFGNSQAQDVLDWVPITHLRTSEQSSCQIPVALEIEVKWTKYGSLVNPQARIVNVTATTTTTTLKQLPLGRERTIPITSSVVFTDISSPAEPGYKAWPTINAKLPHDFFFPFV", "length": 581, "header": "tr|A0A8V1A5X0-1|A0A8V1A5X0_CHICK Isoform 1 of Tectonic family member 1 OS=Gallus gallus OX=9031 GN=TCTN1 PE=3 SV=1 CANONICAL=A0A8V1A5X0-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A5X0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5X0/entry#A0A8V1A5X0-1", "sequence": { "sequence": "MAAALRLGLLLFLSPLRAAEPSTELPSSPEASSKTRATAWKRGRSGPAPLTDVAKLCVCDLLVAQCDVNCCCDPDCSAEDFSLFTTCSVPIVTGDSRLCSQKAAIYSLDTEANPPERVFKLVDHINPSVFCIHATNYEQALSFSSPETPTAENFDQLLKKYGGATFSAEPNSWSMNSDASDPSDANKSYRYEYGVPIQTVDAFLRLPSPVVSSWCSDANPAGFLVHQATKCIRSISVENCGNIQAVSMLFYINSSILAVPKSSQMVNITVQSVVVQSLNGMRTLLNSRDVLRHPMILDELCINIVLGVSYHITYTDTGEIIEAAASFVLGAVNKEALSVQQSFEISFTQVNTNPVPFSGNPGYVVGLAVRAGFKPQGYPFPIVILLSVLFLDQLHSDFLSWTPYIFHLFFTESKCVLFGYILEVTNVSVLTAISWNCSARITAAMNCQPLAQVLLDLLMGQSFPEYVAPFGNSQAQDVLDWVPITHLRTSEQSSCQIPVALEIEVKWTKYGSLVNPQARIVNVTATTTTTTLKQLPLGRERTIPITSSVVFTDISSPAEPGYKAWPTINAKLPHDFFFPFV", "length": 581, "header": "tr|A0A8V1A5X0-1|A0A8V1A5X0_CHICK Isoform 1 of Tectonic family member 1 OS=Gallus gallus OX=9031 GN=TCTN1 PE=3 SV=1 CANONICAL=A0A8V1A5X0-1" }, "locus": { "chromosome": "15", "start_pos": 6005305, "end_pos": 5994413, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010062432.1", "url": "https://www.ensembl.org/id/ENSGALT00010062432.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038602.1", "url": "https://www.ensembl.org/id/ENSGALP00010038602.1" } ] } }, { "isoform_ac": "A0A8V1AB06-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5X0/entry#A0A8V1AB06-1", "sequence": { "sequence": "MAAALRLGLLLFLSPLRAAEPSTELPSSPEASSKTRATAWKRGRSGPAPLTDVAKLCVCDLLVAQCDVNCCCDPDCSAEDFSLFTTCSVPIVTGDSRLCSQKAAIYSLDTEANPPERVFKLVDHINPSVFCIHATNYEQALSFSSPETPTAENFDQLLKKYGGATFSAEPNSWSMNSDASDPSDANKSYRYEYGVPIQTVDAFLRLPSPVVSSWCSDANPAGFLVHQATKCIRSISVENCGNIQAVSMLFYINSSILAVPKSSQMVNITVQSVVVQSLNGMRTLLNSRDVLRHPMILDELCINIVLGVSYHITYTDTGEIIEAAASFVLGAVNKEALSVQQSFEISFTQVNTNPVPFSGNPGYVVGLAVRAGFKPQGSGIIQNTNKYGQLTILQSTAHQDCLTAQEARTPVLFGYNMISGCKLRITAAMNCQPLAQVLLDLLMGQSFPEYVAPFGNSQAQDVLDWVPITHLRTSEQSSCQIPVALEIEVKWTKYGSLVNPQARIVNVTATTTTTTLKQLPLGRERTIPITSSVVFTDISSPAEPGYKAWPTINAKLPHDFFFPFV", "length": 565, "header": "tr|A0A8V1AB06-1|A0A8V1AB06_CHICK Computationally mapped isoform of Tectonic family member 1 OS=Gallus gallus OX=9031 GN=TCTN1 PE=3 SV=1 CANONICAL=A0A8V1A5X0-1" }, "locus": { "chromosome": "15", "start_pos": 6005305, "end_pos": 5994413, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010062434.1", "url": "https://www.ensembl.org/id/ENSGALT00010062434.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038604.1", "url": "https://www.ensembl.org/id/ENSGALP00010038604.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:416870", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416870", "resource": "KEGG Pathway" }, { "id": "R-GGA-5620912", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5620912", "resource": "Reactome", "description": "Anchoring of the basal body to the plasma membrane" } ], "orthologs": [ { "uniprot_canonical_ac": "A0ABK0M228-1", "protein_name": "Tectonic family member 1", "gene_name": "Tctn1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGSRCLPPLLLVLLNCCTSSSTQVVATPAAATPVVTNEDLNFTEATPVVTNEDLNFTEATPVVTNEDLNFTEATPVVTNEDLNFTEATPATLRPSWSPRTPGTPRPPELSGPRPTPVTDVAALCVCDLLPAQCDINCCCDPDCSPGDFSVFSACSIPVVTGDRQFCSQKAAFYSMNLTADPPHRDFKLIDQINPSIFCIHISNYKPALSFANPEVPDENNFDRLMGASGGFTLSAESGVPSTATSDDPQPTKYEYGALLQTAGESSGSFLKLPSPLTSSLCADENPAAFLVNQAFECSRRVAIEECERMEALSMAHYSSPAILRVPNSTTQVSIKIQSIMYRSLNHTLTQLEGRGILRPSLVSTGQDRLCSNVVLQVKYSLLYTASGQIQEAGLSLVLGTLISTVSLLQQKFEIHFIQHGTKPVPLSGNPGYRVGLPLAAGFQPQKGSGIIQTTNRQGQLTILRSTGKQDCLASHGQRAPVLFGYNVQSGCQLRLTGTIPCGLLAQKMQDLLRGQAFPDYVAAFGNSRAQDVQDWVPVHFVTHSSNTKGSCQLPVALGIEVKWTKYGSLLNPQARIVNVTAQLISIPEPLPGPERTMVISTAVTFVDVSAPAEAGFRAPPTINARLPFSFFFPFV", "length": 635 }, "evidence": [ { "id": "A0A8V1A5X0", "url": "https://omabrowser.org/oma/group/A0A8V1A5X0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1MFC9-1", "protein_name": "Tectonic family member 1", "gene_name": "TCTN1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGPRAVPRLLLVLLDCWASVSAQAGTTPVVTTEGLNSTKPVPTTLRSVISSKPPEIPRASRPFSGPRPAPVTDVAALCVCDLSPAQCDVNCCCDPDCSSVDFSVFSACSIPVVTGDSHFCSQKAAVYSLNFTADPPQRVFKLVDQINPSIFCVHITNYKPALSFINPEVTDESSFDKLMKAPDGFSLNAESDVSTRLDAPQTAKYEYGVPLQTSDSFLRFPSPLTSSLCTDNNPAAFLVNQAVKCTRRINLEHCEEMETLSMAYYSSPKILRVPGSGIEVPIMVQSIVIRSLNKTLTRLEDTEILRVSKQGVVEAGHIKICTNVVLEVMYSLTYTDTGEVIKADLFLLLGAVSSAMVPLQQKFEIYFIQQNAKPVPLSGNPGYVVGLPLVAGFQPQKGSGIIQTTNRYGQLTLLRSTTEQDCLAAEGIRAPVLFGYNMQSGCKLRLTKALTCRLVAQKMKSLLKGQGFPDYVAPFGNSQAQDVLDWVPVYFITQTSHVKDSCQLPVALTVEVKWTKYGSLLNPQAKIVNVTARLISSSFPETNSGNERTILISTAVTFVDVSAPAEAGFRARPTINARLPFNFFFPFV", "length": 588 }, "evidence": [ { "id": "A0A8V1A5X0", "url": "https://omabrowser.org/oma/group/A0A8V1A5X0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q2MV58-1", "protein_name": "Tectonic-1", "gene_name": "TCTN1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRPRGLPPLLVVLLGCWASVSAQTDATPAVTTEGLNSTEAALATFGTFPSTRPPGTPRAPGPSSGPRPTPVTDVAVLCVCDLSPAQCDINCCCDPDCSSVDFSVFSACSVPVVTGDSQFCSQKAVIYSLNFTANPPQRVFELVDQINPSIFCIHITNYKPALSFINPEVPDENNFDTLMKTSDGFTLNAESYVSFTTKLDIPTAAKYEYGVPLQTSDSFLRFPSSLTSSLCTDNNPAAFLVNQAVKCTRKINLEQCEEIEALSMAFYSSPEILRVPDSRKKVPITVQSIVIQSLNKTLTRREDTDVLQPTLVNAGHFSLCVNVVLEVKYSLTYTDAGEVTKADLSFVLGTVSSVVVPLQQKFEIHFLQENTQPVPLSGNPGYVVGLPLAAGFQPHKGSGIIQTTNRYGQLTILHSTTEQDCLALEGVRTPVLFGYTMQSGCKLRLTGALPCQLVAQKVKSLLWGQGFPDYVAPFGNSQAQDMLDWVPIHFITQSFNRKDSCQLPGALVIEVKWTKYGSLLNPQAKIVNVTANLISSSFPEANSGNERTILISTAVTFVDVSAPAEAGFRAPPAINARLPFNFFFPFV", "length": 587 }, "evidence": [ { "id": "A0A8V1A5X0", "url": "https://omabrowser.org/oma/group/A0A8V1A5X0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BZ64-1", "protein_name": "Tectonic-1", "gene_name": "Tctn1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGSRGLPPLLLVLLNCYTSSSTQVIAIPAAATPAVTKEDLNSTKATPTTLQPSLSPRTPGTPRAPERSGPRPTPVTDVAALCVCDLLPAQCDVNCCCDPDCSPADFSIFSACSVPVVTGDRQFCSQKAAFYSMNLTADPPHRDFKLIDQINPSVFCIHISNYKPALSFANPEVPDENNFDRLMQTSGGFTLSAESAVPSTAASDGPQPTKYEYGAPLQTAGASSGSFLKLPSPLTSSLCADQNPAAFLVSQAFECSRRVDIEQCEGMEALSMAHYSSPAILRVPNSMTQVSIKIQSVMYRSLNHTLTQLEGHGVLRPSLVSTGQDRLCSNVVLQVKYSLLYTATGQIHEAGLSLVLGTLSSAVSLLQQKFEIHFIQHGTKPVPLSGNPGYRVGLPLAAGFQPQKGSGIIQTTNRQGQFTILRSTSQQDCLASEGLRTPVLFGYNVQSGCQLRLTGTIPCGLLAQKVQDLLRGQAFPDYVAAFGNSRAQDVQDWVPVHFVTYSSNMKGSCQLPVALAIEVKWTKYGSLLNPQARIVNVTAQLVSVPEPLPGPERTVVISTAVTFVDVSAPAEAGFRAPPTINARLPFSFFFPFV", "length": 593 }, "evidence": [ { "id": "A0A8V1A5X0", "url": "https://omabrowser.org/oma/group/A0A8V1A5X0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A5X0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5X0" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A5X0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5X0" } ], "pmid": "" }, { "name": "MKS complex", "id": "GO:0036038", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036038", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A5X0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5X0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "cilium assembly", "id": "GO:0060271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060271", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A5X0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5X0" } ], "pmid": "" }, { "name": "protein localization to ciliary transition zone", "id": "GO:1904491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904491", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A5X0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5X0" } ], "pmid": "" }, { "name": "cell projection organization", "id": "GO:0030030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030030", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A5X0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5X0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 186, "end_pos": 188, "annotation": "n_glycosylation_sequon" }, { "start_pos": 253, "end_pos": 255, "annotation": "n_glycosylation_sequon" }, { "start_pos": 267, "end_pos": 269, "annotation": "n_glycosylation_sequon" }, { "start_pos": 426, "end_pos": 428, "annotation": "n_glycosylation_sequon" }, { "start_pos": 436, "end_pos": 438, "annotation": "n_glycosylation_sequon" }, { "start_pos": 522, "end_pos": 524, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1A5X0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5X0" }, { "id": "PF07773", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07773" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Tectonic-1-3", "eco_id": "ECO_0000259", "start_pos": 190, "end_pos": 350, "start_aa": "Arg", "end_aa": "Val", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1A5X0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5X0" }, { "id": "PF25752", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25752" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Tectonic-1-3 N-terminal", "eco_id": "ECO_0000259", "start_pos": 49, "end_pos": 154, "start_aa": "Pro", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 186, "end_pos": 188 }, { "start_pos": 253, "end_pos": 255 }, { "start_pos": 267, "end_pos": 269 }, { "start_pos": 426, "end_pos": 428 }, { "start_pos": 436, "end_pos": 438 }, { "start_pos": 522, "end_pos": 524 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { 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"total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A5Y5-1", "uniprot_ac": "A0A8V1A5Y5", "uniprot_id": "A0A8V1A5Y5_CHICK", "mass": { "chemical_mass": 56716.0, "monoisotopic_mass": 56716.0 }, "refseq": { "ac": "XP_003642799", "name": "prickle-like protein 4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642799" }, "gene_names": [ { "name": "PRICKLE4", "type": "recommended", "evidence": [ { "id": "A0A8V1A5Y5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5Y5" } ] }, { "name": "PRICKLE4", "type": "synonym", "evidence": [ { "id": "XP_003642799", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642799" } ] } ], "protein_names": [ { "name": "Prickle planar cell polarity protein 4", "type": "synonym", "evidence": [ { "id": "A0A8V1A5Y5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5Y5/entry#names_and_taxonomy" } ] }, { "name": "prickle-like protein 4", "type": "synonym", "evidence": [ { "id": "XP_003642799", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642799" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052557.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_003642799.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003642799", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642799" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A5Y5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5Y5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PRICKLE4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5Y5", "locus": {} } ], "crossref": [ { "id": "A0A8V1A5Y5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A5Y5", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd09340", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09340", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd09341", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09341", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100859351", "url": "https://www.ncbi.nlm.nih.gov/gene/100859351", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001781", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001781", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010442", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010442", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047120", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047120", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:100859351", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100859351", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ISISHSM", "url": "https://omabrowser.org/oma/group/ISISHSM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A5Y5", "url": "https://www.orthodb.org/?gene=A0A8V1A5Y5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24211", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24211", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24211:SF35", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24211:SF35", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00412", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00412", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF06297", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06297", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003642799", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642799", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1A5Y5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5Y5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A5Y5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5Y5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSWPSPAWPQRDEPPPCGTATALPPASSDSDSGCALEEYPESTAEPAPPEVPACFESRPPGSPRPADRSLLRVRALLQQLPPQDCDERYCPDLEEEERKQLRAFSARRRRDALGQGVAVPVPGARHGCPCRKCGGRLSKGDLGIAASRLGGQLWHPPCFCCHVCHQPLVDLIYFQQDERIYCGRHHAELFRPRCASCDQLIFLEECIEAEGRRWHPEHFCCLECDAPLCGQRYVMRSGRPCCRSCFDSLFAEPCQACGEPIGVDSEEATHQGLHWHTRAACFCCSLCRKPLRGQPLTARCGRLFCSESCSLGWDVSSAASTTSDSSDSAFVSAPSPDSTPVSRASHATRAGSTAAAGGCRQRVEGAEMLPDQASTHPAFRSPEDHGAAVERSKDAVCAGVPGSSSSHPSNLQPNTEGPCRLLGGPEPRTLVGDGNPHFQVGLSPARPSPDLEDADPQDIMEEDDSWCPTCSSSSDSDSDEEGFFFGKPIPKPGMNFVGREPQRLERAGCRMAKLRGSSKHCSVS", "length": 524, "header": "tr|A0A8V1A5Y5-1|A0A8V1A5Y5_CHICK Isoform 1 of Prickle planar cell polarity protein 4 OS=Gallus gallus OX=9031 GN=PRICKLE4 PE=4 SV=1 CANONICAL=A0A8V1A5Y5-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A5Y5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5Y5/entry#A0A8V1A5Y5-1", "sequence": { "sequence": "MSWPSPAWPQRDEPPPCGTATALPPASSDSDSGCALEEYPESTAEPAPPEVPACFESRPPGSPRPADRSLLRVRALLQQLPPQDCDERYCPDLEEEERKQLRAFSARRRRDALGQGVAVPVPGARHGCPCRKCGGRLSKGDLGIAASRLGGQLWHPPCFCCHVCHQPLVDLIYFQQDERIYCGRHHAELFRPRCASCDQLIFLEECIEAEGRRWHPEHFCCLECDAPLCGQRYVMRSGRPCCRSCFDSLFAEPCQACGEPIGVDSEEATHQGLHWHTRAACFCCSLCRKPLRGQPLTARCGRLFCSESCSLGWDVSSAASTTSDSSDSAFVSAPSPDSTPVSRASHATRAGSTAAAGGCRQRVEGAEMLPDQASTHPAFRSPEDHGAAVERSKDAVCAGVPGSSSSHPSNLQPNTEGPCRLLGGPEPRTLVGDGNPHFQVGLSPARPSPDLEDADPQDIMEEDDSWCPTCSSSSDSDSDEEGFFFGKPIPKPGMNFVGREPQRLERAGCRMAKLRGSSKHCSVS", "length": 524, "header": "tr|A0A8V1A5Y5-1|A0A8V1A5Y5_CHICK Isoform 1 of Prickle planar cell polarity protein 4 OS=Gallus gallus OX=9031 GN=PRICKLE4 PE=4 SV=1 CANONICAL=A0A8V1A5Y5-1" }, "locus": { "chromosome": "26", "start_pos": 5013629, "end_pos": 5011257, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010064281.1", "url": "https://www.ensembl.org/id/ENSGALT00010064281.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039488.1", "url": "https://www.ensembl.org/id/ENSGALP00010039488.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:100859351", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100859351", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A5Y5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5Y5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1A5Y5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5Y5" }, { "id": "PS50023", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50023" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "LIM zinc-binding", "eco_id": "ECO_0000259", "start_pos": 128, "end_pos": 191, "start_aa": "Cys", "end_aa": "Arg", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1A5Y5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5Y5" }, { "id": "PS51303", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51303" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PET", "eco_id": "ECO_0000259", "start_pos": 20, "end_pos": 126, "start_aa": "Ala", "end_aa": "His", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A5Y6-1", "uniprot_ac": "A0A8V1A5Y6", "uniprot_id": "A0A8V1A5Y6_CHICK", "mass": { "chemical_mass": 20559.0, "monoisotopic_mass": 20559.0 }, "refseq": {}, "gene_names": [ { "name": "SSNA1", "type": "recommended", "evidence": [ { "id": "A0A8V1A5Y6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5Y6" } ] } ], "protein_names": [ { "name": "SS nuclear autoantigen 1", "type": "synonym", "evidence": [ { "id": "A0A8V1A5Y6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5Y6/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A5Y6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5Y6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SSNA1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5Y6", "locus": {} } ], "crossref": [ { "id": "A0A8V1A5Y6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A5Y6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000048501", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000048501", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR033362", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033362", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR28661", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28661", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR28661:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28661:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF27720", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27720", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A3Q2U7G7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U7G7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2U7G7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U7G7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A5Y6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5Y6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A5Y6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5Y6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSGAGEALQGYNAALLEGLAELRARRDELSGRIREEEAERERLQSRIAALTERLARSSERTARHLAARRQLDACIAESEAAYGKVRPSRIPAERRGCELRERERAPLGGRKKVVWCGRWGAARVARRGGGAPSLQTAEVGMELRVSLCAAGSGNRRPLMIPSNSNHSDSVCPILHTVTAEFSSHPKPQ", "length": 188, "header": "tr|A0A8V1A5Y6-1|A0A8V1A5Y6_CHICK Isoform 1 of SS nuclear autoantigen 1 OS=Gallus gallus OX=9031 GN=SSNA1 PE=4 SV=1 CANONICAL=A0A8V1A5Y6-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2U7G7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5Y6/entry#A0A3Q2U7G7-1", "sequence": { "sequence": "ALQGYNAALLEGLAELRARRDELSGRIREEEAERERLQSRIAALTERLARSSERTARHLAARRQLDACIAESEAAYGKILESSQTLLDAVKGEIGNASKASEPASTSKQTPGQKHS", "length": 116, "header": "tr|A0A3Q2U7G7-1|A0A3Q2U7G7_CHICK Computationally mapped isoform of SS nuclear autoantigen 1 OS=Gallus gallus OX=9031 GN=SSNA1 PE=4 SV=1 CANONICAL=A0A8V1A5Y6-1" }, "locus": { "chromosome": "17", "start_pos": 2458216, "end_pos": 2455863, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067575.1", "url": 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"id": "A0A8V1A5Z6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5Z6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A5Z6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5Z6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRGEREHLRAREGSGNVVPSAQGGRWDGGGRRRPGCWGCSLSLTPLSVPGAMPAGGRELLVLGLLALGCAAANDFPEGVVGRRRPPGPAPGCPRDCGCTQEGVVDCGGIDLKEFPLLLPELTNHLSLQNNQIEEIFPEELARLHRLETLNLQNNRLTSKGLPEEAFEHLENLNYLYLANNKLTVAPKFLPNTLISADFAANYLTKIYGLTFGQKPNLRSVYLHNNKLSDAGLPDNMFNGSNNVEILIMSSNFLKYVPKNLPPALYKLHLKNNKLEKIPKGAFSELTGLRELYLQNNYLTNEGMDNETFWKLSSLEYLDLSSNNLSQIPSGLPRNIVLLHLEKNAIKVIGRDVLTQIKNLEYLLLHNNKLKARGIHPSAFHGLKKLHTVHLYNNLLERIPSGLPRRVKTLMILHNQISEINRNDFATTYFLEELNLSYNKLKSPQIHREAFRKLRQLKSLDLSGNNLNTVPYGFPKNLQVLKLKENEISDIPKGTLSGMTKLRELYLSNNKLKVNSIYSRAWKELSSLQSLDMAGNQLTSIPSGLPESLEYLYLQNNKITVVSENVFESTPKLKGIYLRFNKIAVGALKVNTFQSLQHLQVLDIEGNLEFSNTSKNKDDSEEELEDEEDEEN", "length": 631, "header": "tr|A0A8V1A5Z6-1|A0A8V1A5Z6_CHICK Isoform 1 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"tr|A0A8V1A613-1|A0A8V1A613_CHICK Isoform 1 of Coiled-coil domain containing 66 OS=Gallus gallus OX=9031 GN=CCDC66 PE=4 SV=1 CANONICAL=A0A8V1A613-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A613-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A613/entry#A0A8V1A613-1", "sequence": { "sequence": "MNLGDGLKLETEVLDGKPRLILAASDKAKPAMKMGNKARVPKQTLRIRHIGHMQRSTQNACINQENLAKPRSGSSLSVSKGERLQVTKPSLHEATTKDHSLIFQRDTTNRKPDSENLNVKESKHDPQNTHISAEDVRSLVCLTQEQLQQILMIVKGGTRHISETPNEKQEEMGTSEASEETTVALLQKACEVASVPDEPNSNSSRKQESYPQPREKVIKESWKPADMFSTLGEREGEKALLESKKTQWKKELDEQVALKKKLKETLEGDVVYLWTKSGNDKNHTEKMETADPDKEAVPQEQPFSSLKHEQQKKWLEELDKQKEEAKLRKIEEKMNLSKAEEHDRWAMHFDSLKNHLNTNAQHPLNGMYKKQPESLCLSPDPKELTAFVHPFSPAALGNFMPSKVGNAEKGAKSSALDHSQKTSFLRSMTALLDPAQIEERDRRRQKQLEHQKAIMAQVEEKRKKKQLEEEKRKLEEQEEEQRLAREKERMQKQFEEDMLKQKQKEELVILKTNELYQTMQKAQELAQRLKQEQRIQDLAQKGHDISKLKKNLGGGGGEFENCNADVSHQCPNFSDGVNIDQQTSPRKDTAVQTDDYTTSAYIDTAEERTSCCGSPDISIEYKETSNSKKYQKEMQYMYKNRISGQENGGIYSELYEQYARKERQVKPSEKPGKRPDWNINKPEKRYIPASERYPKPLQKQREENKVRRQMELLQLVQRNTPGNLCQKRGCCSDRSPSPHEELKNKGHRIRKEEQLHKNHLNEERSDSPPVPAVKNRLQVQQKQICARKLEVYNNSRREKNTKVDIQQKSFPPPVTEAGRPPSSQFIPYVRTNEVYYLDPDAPVTRPSTHDPQYRQFNDSYHVPRQIFSSDHTRDPLLNPDVVKIRERQQAILKGLSELRQGLLQKQKELESGLIPVKAQEENFISPF", "length": 927, "header": "tr|A0A8V1A613-1|A0A8V1A613_CHICK Isoform 1 of Coiled-coil domain containing 66 OS=Gallus gallus OX=9031 GN=CCDC66 PE=4 SV=1 CANONICAL=A0A8V1A613-1" }, "locus": { "chromosome": "12", "start_pos": 8574554, "end_pos": 8558775, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067605.1", "url": "https://www.ensembl.org/id/ENSGALT00010067605.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041348.1", "url": "https://www.ensembl.org/id/ENSGALP00010041348.1" } ] } }, { "isoform_ac": "A0A8V1AI37-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A613/entry#A0A8V1AI37-1", "sequence": { "sequence": "MGNKARVPKQTLRIRHIGHMQRSTQNACINQENLAKPRSGSSLSVSKGERLQVTKPSLHEATTKDHSLIFQRDTTNRKPDSENLNVKESKHDPQNTHISAEDVRSLVCLTQEQLQQILMIVKGGTRHISETPNEKQEEMGTSEASEETTVALLQKACEVASVPDEPNSNSSRKQESYPQPREKVIKESWKPADMFSTLGEREGEKALLESKKTQWKKELDEQVALKKKLKETLEGDVVYLWTKSGNDKNHTEKMETADPDKEAVPQEQPFSSLKHEQQKKWLEELDKQKEEAKLRKIEEKMNLSKAEEHDRWAMHFDSLKNHLNTNAQHPLNGMYKKQPESLCLSPDPKELTAFVHPFSPAALGNFMPSKVGNAEKGAKSSALDHSQKTSFLRSMTALLDPAQIEERDRRRQKQLEHQKAIMAQVEEKRKKKQLEEEKRKLEEQEEEQRLAREKERMQKQFEEDMLKQKQKEELVILKTNELYQTMQKAQELAQRLKQEQRIQDLAQKGHDISKLKKNLGGGGGEFENCNADVSHQCPNFSDGVNIDQQTSPRKDTAVQTDDYTTSAYIDTAEERTSCCGSPDISIEYKETSNSKKYQKEMQYMYKNRISGQENGGIYSELYEQYARKERQVKPSEKPGKRPDWNINKPEKRYIPASERYPKPLQKQREENKVRRQMELLQLVQRNTPGNLCQKRGCCSDRSPSPHEELKNKGHRIRKEEQLHKNHLNEERSDSPPVPAVKNRLQVQQKQICARKLEVYNNSRREKNTKVDIQQKSFPPPVTEAGRPPSSQFIPYVRTNEVYYLDPDAPVTRPSTHDPQYRQFNDSYHVPRQIFSSDHTRDPLLNPDVVKIRERQQAILKGLSELRQGLLQKQKELESGLIPVKAQEENFISPF", "length": 894, "header": "tr|A0A8V1AI37-1|A0A8V1A613_CHICK Computationally mapped isoform of Coiled-coil domain containing 66 OS=Gallus gallus OX=9031 GN=CCDC66 PE=4 SV=1 CANONICAL=A0A8V1A613-1" }, "locus": { "chromosome": "12", "start_pos": 8574554, "end_pos": 8560851, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067606.1", "url": "https://www.ensembl.org/id/ENSGALT00010067606.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041349.1", "url": "https://www.ensembl.org/id/ENSGALP00010041349.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0ABK0LS77-1", "protein_name": "Coiled-coil domain containing 66", "gene_name": "Ccdc66", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNLGDGLKLETELLDGKTKLILSPYEHKSKVSVKMGNKIKIAKYSLRTKQTGHTLKSTQNTYIGSENLSQKKISTSDTSQAKRENSRLTFSSPSTDLCKQYSEKDCLRVQKEISPTASSIRKTVNTSTDTDPAAKQKPCRKPTAAEGMGSGLVCLTQDQLRQILMLSVNQGNGSMSLPENGEEVTSQDSLHLISIPSQPKEVSVTGLLQKTEAVSPVARENEPVPQRAQAASQQCEQKATVESEWKPADIFSTLGERERDRSLLEARRAQWKKELDEQVALKKKEKEASQKWPDPWKPSEILCEKLQVLERSKEAGLLESPCITVKQEQQRKWIEELNKQVEDDQQRKAEEKLIYSKGEEHDRWAVHFDSFKSHPGSQSRLSSQLTPQHLESLCVSPDTQELADVSSVDTPPPAVQVKPSEKEQRARPVMDMSVSHGQKTNFLRSMTALLDPAQIEERERRRQKQLEHQKAITAQVEENRRKKRLEEEQRRKEEQEEELRLAREREEMQRQYEEDILKQKHKEEIMTLKTNELFHTMQRAQELAQRLKQEQRIRELTQKGHDTSRLIQNLGAHVDCKASTPVSSSRDTEEAANDTRAAATSTASPKKDTGVQTDDVNLGIFNDGLPHCGSVTEWGVRNLSSPEISAEFSGQTGIRKEKQELSMDKGTHLDKENSWYNNRCTQHRRTEKQTKLVKKCPKKPAWNINKPLKRYVPASAKYPAHLQKEKEERKVRRQMELLHLVQRNDPETLSQNNGASPDIFVSSHREAESEMRLHLLKKVEEPLETSVSKERFQTSPAVKSRTQQTQSNILHLPPKNSDYEKETLTLGDGHTKLSDERSEPSHFIPYVRTNEIYYLDPDAPLSRPSTQDNQYQKSHDCGGGQELFDSDHIRDPLLNPKLVKSRDRQQAILRGLSELRQVGTLHQGTVFTCLFSLWWQCLYPSF", "length": 942 }, "evidence": [ { "id": "A0A8V1A613", "url": "https://omabrowser.org/oma/group/A0A8V1A613/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A2RUB6-1", "protein_name": "Coiled-coil domain-containing protein 66", "gene_name": "CCDC66", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNLGDGLKLETELLDGKTKLILSPYEHKSKISVKMGNKAKIAKCPLRTKTGHILKSTQDTCIGSEKLLQKKPVGSETSQAKGEKNGMTFSSTKDLCKQCIDKDCLHIQKEISPATPNMQKTRNTVNTSLVGKQKPHKKHITAENMKSSLVCLTQDQLQQILMTVNQGNRSLSLTENGKEAKSQYSLYLNSISNQPKDENIMGLFKKTEMVSSVPAENKSVLNEHQETSKQCEQKIAIENEWKPADIFSTLGERECDRSSLEAKKAQWRKELDEQVALKKKEKEVSEKWNDPWKKSESDKIIWEKHQILDQSRETVLLEHPFSAVKQELQRKWIEELNKQIEDDRQRKIEEKIIYSKGEEHDRWAMHFDSLKSYPGSQSQLFSQSTHKQPEYFCVSPDTQELADVSSVCTPTTGSQVEPSEEEHIAKPIKDVVMANSKKTNFLRSMTALLDPAQIEERDRRRQKQLEHQKAITAQVEEKRRKKQLEEEQRKKEEQEEELRLAQEREEMQKQYEEDILKQKQKEEIMTLKTNELFQTMQRAQELAQRLKQEQRIRELAQKGHDTSRLIKNLGVDTIQMEYNASNISNSRHDSDEISGKMNTYMNSTTSKKDTGVQTDDLNIGIFTNAESHCGSLMERDITNCSSPEISAELIGQFSTKKNKQELTQDKGASLEKENNRCNDQCNQFTRIEKQTKHMKKYPKRPDWNINKPPKRYIPASEKYPKQLQKQREEKKVRRQMELLHLVEKNNPGHLSQNRGISPEIFHSSHQETESKLRWHLVKKEEEPLNIHSFSKERSPSSPVPVVKNRTQQTQNTLHLPLKNSSYERENLISGSNQTELSSGISESSHFIPYVRTNEIYYLDPDAPLSGPSTQDPQYQNSQDCGQKRQLFDSDCVRDPLLNPNMVKNRDRQQAILKGLSELRQGLLQKQKELESSLLPLAENQEESFGSSF", "length": 948 }, "evidence": [ { "id": "A0A8V1A613", "url": "https://omabrowser.org/oma/group/A0A8V1A613/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6NS45-1", "protein_name": "Coiled-coil domain-containing protein 66", "gene_name": "Ccdc66", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNLGDGLKLETELLDGKTKLILSPYEHKSKVSVKMGNKFKIAKCPLRTKQTGHTLKSTQNTYIGNENLSQKKISTLDTSQAKPENSRLTFSPSTDKQYSEKDSVRVQKEISPTTSNIRKIINTTGTCPVAKQKPCKKNPTAETMNSGLVCLTQDQLRQILMLSVNQGNGSVCLTETGEEEASQDSLHLINIPSQPKDVNDTGFLQNTEAASPVTSEHEHVHRRAQEAFQQCEQKAATENEWKPADIFSTLGERERDKSLLEARRAQWKKELDEQVALKKKEKEASQKWHNPWKPSDIECEKSQVHDQSKEARLLESPCSAIKQEQQRKWIEELNKQVEDDQQRKAEERMIYSKGEEHDRWAVHFDSLKSHPGSQSRLSSQLTHQHLESLCVSPDTQELADVNGVFTPPPGVQAEPSEKEQRARPVLEMAVSHGPKTNFLRSMTALLDPAQIEERERRRQKQLEHQKAIMAQVEENRRKKRLEEEQRKKEEQELELRLAREREEMQRQYEEDILKQRQREEIMTLKTNELFHTMQRAQELAQRLKQEQRIRELAQKGHDTSRLIQNLGAQVDYKAFTTISSSHSDPEETADTSTASPKKDTGVQTDDVNLGIFNDALPPCGSVTEKGIRNISSPEISAEFSGQTDIRKENQELSMNKGTNLDKENSWHNGQCNQYRRTEKQTKLMKKCPKKPAWNINKPLKKYVPASAKYPAHLQKEKEEKKVQRQMELLHLVERNNPENLSQNRGISPLATSHRETESESRLHLIKKVEEPLKTPSVSKERFQTSPAVKNRTQQTQSNVLHLPLKNNDYEKETLTLGDGHTKLSDEMSEPSHFIPYVRTNEIYYLDPDAPLSRPSTQDNQYQKSHDCAREQELFDSDHIRDPLLNPKLVKNRDRQQAILKGLSELRQGLLQKQKELETNLIPLTANQEDNFSSSF", "length": 935 }, "evidence": [ { "id": "A0A8V1A613", "url": "https://omabrowser.org/oma/group/A0A8V1A613/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 8, "go_terms": [ { "name": "spindle", "id": "GO:0005819", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005819", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A613", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A613" } ], "pmid": "" }, { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A613", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A613" } ], "pmid": "" }, { "name": "cilium", "id": "GO:0005929", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005929", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A613", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A613" } ], "pmid": "" }, { "name": "photoreceptor inner segment", "id": "GO:0001917", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001917", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A613", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A613" } ], "pmid": "" }, { "name": "axoneme", "id": "GO:0005930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005930", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A613", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A613" } ], "pmid": "" }, { "name": "midbody", "id": "GO:0030496", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030496", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A613", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A613" } ], "pmid": "" }, { "name": "centriolar satellite", "id": "GO:0034451", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034451", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A613", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A613" } ], "pmid": "" }, { "name": "ciliary basal body", "id": "GO:0036064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036064", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A613", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A613" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A613", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A613" } ], "pmid": "" }, { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A613", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A613" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 10, "go_terms": [ { "name": "mitotic spindle assembly", "id": "GO:0090307", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090307", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A613", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A613" } ], "pmid": "" }, { "name": "cilium assembly", "id": "GO:0060271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060271", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A613", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A613" } ], "pmid": "" }, { "name": "microtubule nucleation", "id": "GO:0007020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A613", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A613" } ], "pmid": "" }, { "name": "mitotic metaphase chromosome alignment", "id": "GO:0007080", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007080", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A613", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A613" } ], "pmid": "" }, { "name": "establishment of mitotic spindle orientation", "id": "GO:0000132", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000132", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A613", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A613" } ], "pmid": "" }, { "name": "detection of light stimulus involved in visual perception", "id": "GO:0050908", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050908", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A613", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A613" } ], "pmid": "" }, { "name": "regulation of cytokinesis", "id": "GO:0032465", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032465", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A613", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A613" } ], "pmid": "" }, { "name": "ciliary transition zone assembly", "id": "GO:1905349", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905349", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A613", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A613" } ], "pmid": "" }, { "name": "microtubule bundle formation", "id": "GO:0001578", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001578", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A613", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A613" } ], "pmid": "" }, { "name": "regulation of protein localization to cilium", "id": "GO:1903564", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903564", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A613", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A613" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 202, "end_pos": 204, "annotation": "n_glycosylation_sequon" }, { "start_pos": 282, "end_pos": 284, "annotation": "n_glycosylation_sequon" }, { "start_pos": 335, "end_pos": 337, "annotation": "n_glycosylation_sequon" }, { "start_pos": 572, "end_pos": 574, "annotation": "n_glycosylation_sequon" }, { "start_pos": 793, "end_pos": 795, "annotation": "n_glycosylation_sequon" }, { "start_pos": 857, "end_pos": 859, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], 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}, { "start_pos": 572, "end_pos": 574 }, { "start_pos": 793, "end_pos": 795 }, { "start_pos": 857, "end_pos": 859 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": 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"count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { 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"Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A615", "locus": {} } ], "crossref": [ { "id": "A0A8V1A615", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A615", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR001849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PF00169", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00169", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1A615", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A615", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A615-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A615-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A626-1", "uniprot_ac": "A0A8V1A626", "uniprot_id": "A0A8V1A626_CHICK", "mass": { "chemical_mass": 192643.0, "monoisotopic_mass": 192643.0 }, "refseq": { "ac": "XP_015148875", "name": "protein TASOR isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015148875" }, "gene_names": [ { "name": "FAM208A", "type": "recommended", "evidence": [ { "id": "A0A8V1A626", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A626" } ] }, { "name": "FAM208A", "type": "synonym", "evidence": [ { "id": "XP_015148875", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015148875" } ] } ], "protein_names": [ { "name": "Transcription activation suppressor", "type": "synonym", "evidence": [ { "id": "A0A8V1A626", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A626/entry#names_and_taxonomy" } ] }, { "name": "protein TASOR isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015148875", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015148875" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052543.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015148875.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015148875", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015148875" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A626", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A626" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FAM208A", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A626", "locus": {} } ], "crossref": [ { "id": "cd22569", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22569", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "415999", "url": "https://www.ncbi.nlm.nih.gov/gene/415999", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR022188", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022188", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046432", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046432", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056242", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056242", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056243", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056243", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:415999", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415999", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MRQKHEY", "url": "https://omabrowser.org/oma/group/MRQKHEY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A626", "url": "https://www.orthodb.org/?gene=A0A8V1A626", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ADR7", "url": "https://www.orthodb.org/?gene=A0A8V1ADR7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AGA6", "url": "https://www.orthodb.org/?gene=A0A8V1AGA6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16207", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16207", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16207:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16207:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12509", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12509", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23314", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23314", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24630", "url": 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"MTDAAISGGGEMEPEQHQRTEKSGTGLLGVESNSAGAAEDTTQNGGRSEEALLVAAVAAEDEVPPSPSMTSSSQRRSSIPTAHDQQPPPSDVSGGPPPLPKPPEDVPVRRNFQIPRKSREKKALFQPVAVGSREFDDVVKILHSSFLEPSSVSNFNYKRASLVHNELLEKEFTEKRRELKFDGRLDKELSETYAFLMVDRPQIQSICEKGLQVGHSKIAILGSPSMGVYISRYADLLQPNPLETGATGDVIIFKVIKGKMKSIYDHIGMKAMESTVKSALDPTPKHECHVSKNAHKVTSVLAYRAYELTQYYFYEYGFDEIRRRPRHVCPYAVVSFTYKDEIVQAPKFLPPSRSNSFNPDRSTDKFNYTLWRGQLWNKGKLLCHVSLKSAARPFLPCKLPEKLDLEKVVSIDQLKKKISPLLFYKETYVGAKEVLRNGMYSSLYEVVEKSRSGSHLEGLLQKLEKEKLVLVKPLLDRGFLLLLSPWQMASPYDQQTGRSRMLNALFLFPEPRGVTVSAQRSVPCGTQKNSTTAILHENQIIPEFTRFIQSLHFALIQSRKDATADFNTVVEKYINEYLRRCYSGSGKYREFVLYRYESRLDDKKFLYPAPKNKSHIDSCLQNYIFSCAAYELPVSRARELMEGNRKHQQFSPISDYEATEEDSEFAIMKSGRRIHAKSEAAAVKRKFPHLGDYDPERLKDLINLIQCRKKNVGGDSDSEDLRNKSGLKRKLERQPENLPKHLKMSESSENNCQYEGGRSSEPPQTVFSIISGLGGHDTDLRHQDVSDPAVTDTHGLVKLLLETLANSGHMDSSLARSVNQALGLNSDEVEEDMRQNYEYESIPAQDQDDHELPDDAQAEPVNFKDPQSPVMLETDAACLPFAIDVDLRFPASEVGLEHTLLLKEASTGSVSSFEDYSPCPSTPVEHVYRRHHSNSNSIEVGMPWRLIPITGGIGKDEEDQLEKYEDKETGLKSPEEPLVYLPPKDAFPNDPRVINRQRSSDYQFPCSPFSDTQKGTAEDGLYTRQVEKLEDECELADHPFTTQHSISAIVETVILEEYSLFVKKIQEILREKNISYVSGMFTPVVLGQERIMRFSEYVCLQTSEVSVQEYVETLSEKMNSVVLSSSCIRHTPPIYCSPESAEVVHSAAPKPPPNVLPICSDSDMTLLTEPLCNSMVEDADSIEQQSSSLPVVKEEVEHVNAKAEAMLTSDQTPSSGNLMEPPEKTQKSPENLNVSSQPALSDFISQLKPEVFNSLVEIIKDVQKNTVKFYIHEEEESILCKEIKEYLTKLGNTECHPEQFLKRRAALDKLLIIIQNEDIANLIHKVPGLVTLKKLSCVSFAGVDSLDDVKNHTYNELFMSGGFVVSDESVLNPDSITTDKLKQFLQFLEDLNTPDGKWQWKVHCKMQKKLKELGRLNANALSLLTLLNTYQKKHLVEILSYHNCDSQTRNAPELECLIRLQAQSIQQRHIVFLTEKNLKPLSNYADNGIVVATVDDFMQNFTSLVGYHNSVNEEDNPSPSQERQSVHVENDGKDEEDMSLDSGDEASQIEICNDASEYDTRLETLQTETKSSRGVDAKESCVSELSPEARRSLMDKSSKIDMEEIKPITPLSTTHSAEGEKHNSVQRAPFNNFQVYSRQLNMSHQFSHFNVLTHQTFLGAAYPHSTRQNQEGGSYFPSPYSQRRDKEKSSLPGGWDKNCDSSRPYSKRK", "length": 1709, "header": "tr|A0A8V1A626-1|A0A8V1A626_CHICK Isoform 1 of Transcription activation suppressor OS=Gallus gallus OX=9031 GN=FAM208A PE=3 SV=1 CANONICAL=A0A8V1A626-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A626-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A626/entry#A0A8V1A626-1", "sequence": { "sequence": "MTDAAISGGGEMEPEQHQRTEKSGTGLLGVESNSAGAAEDTTQNGGRSEEALLVAAVAAEDEVPPSPSMTSSSQRRSSIPTAHDQQPPPSDVSGGPPPLPKPPEDVPVRRNFQIPRKSREKKALFQPVAVGSREFDDVVKILHSSFLEPSSVSNFNYKRASLVHNELLEKEFTEKRRELKFDGRLDKELSETYAFLMVDRPQIQSICEKGLQVGHSKIAILGSPSMGVYISRYADLLQPNPLETGATGDVIIFKVIKGKMKSIYDHIGMKAMESTVKSALDPTPKHECHVSKNAHKVTSVLAYRAYELTQYYFYEYGFDEIRRRPRHVCPYAVVSFTYKDEIVQAPKFLPPSRSNSFNPDRSTDKFNYTLWRGQLWNKGKLLCHVSLKSAARPFLPCKLPEKLDLEKVVSIDQLKKKISPLLFYKETYVGAKEVLRNGMYSSLYEVVEKSRSGSHLEGLLQKLEKEKLVLVKPLLDRGFLLLLSPWQMASPYDQQTGRSRMLNALFLFPEPRGVTVSAQRSVPCGTQKNSTTAILHENQIIPEFTRFIQSLHFALIQSRKDATADFNTVVEKYINEYLRRCYSGSGKYREFVLYRYESRLDDKKFLYPAPKNKSHIDSCLQNYIFSCAAYELPVSRARELMEGNRKHQQFSPISDYEATEEDSEFAIMKSGRRIHAKSEAAAVKRKFPHLGDYDPERLKDLINLIQCRKKNVGGDSDSEDLRNKSGLKRKLERQPENLPKHLKMSESSENNCQYEGGRSSEPPQTVFSIISGLGGHDTDLRHQDVSDPAVTDTHGLVKLLLETLANSGHMDSSLARSVNQALGLNSDEVEEDMRQNYEYESIPAQDQDDHELPDDAQAEPVNFKDPQSPVMLETDAACLPFAIDVDLRFPASEVGLEHTLLLKEASTGSVSSFEDYSPCPSTPVEHVYRRHHSNSNSIEVGMPWRLIPITGGIGKDEEDQLEKYEDKETGLKSPEEPLVYLPPKDAFPNDPRVINRQRSSDYQFPCSPFSDTQKGTAEDGLYTRQVEKLEDECELADHPFTTQHSISAIVETVILEEYSLFVKKIQEILREKNISYVSGMFTPVVLGQERIMRFSEYVCLQTSEVSVQEYVETLSEKMNSVVLSSSCIRHTPPIYCSPESAEVVHSAAPKPPPNVLPICSDSDMTLLTEPLCNSMVEDADSIEQQSSSLPVVKEEVEHVNAKAEAMLTSDQTPSSGNLMEPPEKTQKSPENLNVSSQPALSDFISQLKPEVFNSLVEIIKDVQKNTVKFYIHEEEESILCKEIKEYLTKLGNTECHPEQFLKRRAALDKLLIIIQNEDIANLIHKVPGLVTLKKLSCVSFAGVDSLDDVKNHTYNELFMSGGFVVSDESVLNPDSITTDKLKQFLQFLEDLNTPDGKWQWKVHCKMQKKLKELGRLNANALSLLTLLNTYQKKHLVEILSYHNCDSQTRNAPELECLIRLQAQSIQQRHIVFLTEKNLKPLSNYADNGIVVATVDDFMQNFTSLVGYHNSVNEEDNPSPSQERQSVHVENDGKDEEDMSLDSGDEASQIEICNDASEYDTRLETLQTETKSSRGVDAKESCVSELSPEARRSLMDKSSKIDMEEIKPITPLSTTHSAEGEKHNSVQRAPFNNFQVYSRQLNMSHQFSHFNVLTHQTFLGAAYPHSTRQNQEGGSYFPSPYSQRRDKEKSSLPGGWDKNCDSSRPYSKRK", "length": 1709, "header": "tr|A0A8V1A626-1|A0A8V1A626_CHICK Isoform 1 of Transcription activation suppressor OS=Gallus gallus OX=9031 GN=FAM208A PE=3 SV=1 CANONICAL=A0A8V1A626-1" }, "locus": { "chromosome": "12", "start_pos": 8606105, "end_pos": 8576793, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067620.1", "url": "https://www.ensembl.org/id/ENSGALT00010067620.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041363.1", "url": "https://www.ensembl.org/id/ENSGALP00010041363.1" } ] } }, { "isoform_ac": "A0A8V1ADR7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A626/entry#A0A8V1ADR7-1", "sequence": { "sequence": "MTDAAISGGGEMEPEQHQRTEKSGTGLLGVESNSAGAAEDTTQNGGRSEEALLVAAVAAEDEVPPSPSMTSSSQRRSSIPTAHDQQPPPSDVSGGPPPLPKPPEDVPVRRNFQIPRKSREKKALFQPVAVGSREFDDVVKILHSSFLEPSSVSNFNYKRASLVHNELLEKEFTEKRRELKFDGRLDKELSETYAFLMVDRPQIQSICEKGLQVGHSKIAILGSPSMGVYISRYADLLQPNPLETGATGDVIIFKVIKGKMKSIYDHIGMKAMESTVKSALDPTPKHECHVSKNAHKVTSVLAYRAYELTQYYFYEYGFDEIRRRPRHVCPYAVVSFTYKDEIVQAPKFLPPSRSNSFNPDRSTDKFNYTLWRGQLWNKGKLLCHVSLKSAARPFLPCKLPEKLDLEKVVSIDQLKKKISPLLFYKETYVGAKEVLRNGMYSSLYEVVEKSRSGSHLEGLLQKLEKEKLVLVKPLLDRGFLLLLSPWQMASPYDQQTGRSRMLNALFLFPEPRGVTVSAQRSVPCGTQKNSTTAILHENQIIPEFTRFIQSLHFALIQSRKDATADFNTVVEKYINEYLRRCYSGSGKYREFVLYRYESRLDDKKFLYPAPKNKSHIDSCLQNYIFSCAAYELPVSRARELMEGNRKHQQFSPISDYEATEEDSEFAIMKSGRRIHAKSEAAAVKRKFPHLGDYDPERLKDLINLIQCRKKNVGGDSDSEDLRNKSGLKRKLERQPENLPKHLKMSESSENNCQYEAQDQDDHELPDDAQAEPVNFKDPQSPVMLETDAACLPFAIDVDLRFPASEVGLEHTLLLKEASTGSVSSFEDYSPCPSTPVEHVYRRHHSNSNSIEVGMPWRLIPITGGIGKDEEDQLEKYEDKETGLKSPEEPLVYLPPKDAFPNDPRVINRQRSSDYQFPCSPFSDTQKGTAEDGLYTRQVEKLEDECELADHPFTTQHSISAIVETVILEEYSLFVKKIQEILREKNISYVSGMFTPVVLGQERIMRFSEYVCLQTSEVSVQEYVETLSEKMNSVVLSSSCIRHTPPIYCSPESAEVVHSAAPKPPPNVLPICSDSDMTLLTEPLCNSMVEDADSIEQQSSSLPVVKEEVEHVNAKAEAMLTSDQTPSSGNLMEPPEKTQKSPENLNVSSQPALSDFISQLKPEVFNSLVEIIKDVQKNTVKFYIHEEEESILCKEIKVPGLVTLKKLSCVSFAGVDSLDDVKNHTYNELFMSGGFVVSDESVLNPDSITTDKLKQFLQFLEDLNTPDGKWQWKVHCKMQKKLKELGRLNANALSLLTLLNTYQKKHLVEILSYHNCDSQTRNAPELECLIRLQAQSIQQRHIVFLTEKNLKPLSNYADNGIVVATVDDFMQNFTSLVGYHNSVNEEDNPSPSQERQSVHVENDGKDEEDMSLDSGDEASQIEICNDASEYDTRLETLQTETKSSRGVDAKESCVSELSPEARRSLMDKSSKIDMEEIKPITPLSTTHSAEGEKHNSVQRAPFNNFQVYSRQLNMSHQFSHFNVLTHQTFLGAAYPHSTRQNQEGGSYFPSPYSQRRDKEKSSLPGGWDKNCDSSRPYSKRK", "length": 1580, "header": "tr|A0A8V1ADR7-1|A0A8V1ADR7_CHICK Computationally mapped isoform of Transcription activation suppressor OS=Gallus gallus OX=9031 GN=FAM208A PE=3 SV=1 CANONICAL=A0A8V1A626-1" }, "locus": { "chromosome": "12", "start_pos": 8606105, "end_pos": 8576793, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067629.1", "url": "https://www.ensembl.org/id/ENSGALT00010067629.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041372.1", "url": "https://www.ensembl.org/id/ENSGALP00010041372.1" } ] } }, { "isoform_ac": "A0A8V1AGA6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A626/entry#A0A8V1AGA6-1", "sequence": { "sequence": "MTDAAISGGGEMEPEQHQRTEKSGTGLLGVESNSAGAAEDTTQNGGRSEEALLVAAVAAEDEVPPSPSMTSSSQRRSSIPTAHDQQPPPSDVSGGPPPLPKPPEDVPVRRNFQIPRKSREKKALFQPVAVGSREFDDVVKILHSSFLEPSSVSNFNYKRASLVHNELLEKEFTEKRRELKFDGRLDKELSETYAFLMVDRPQIQSICEKGLQVGHSKIAILGSPSMGVYISRYADLLQPNPLETGATGDVIIFKVIKGKMKSIYDHIGMKAMESTVKSALDPTPKHECHVSKNAHKVTSVLAYRAYELTQYYFYEYGFDEIRRRPRHVCPYAVVSFTYKDEIVQAPKFLPPSRSNSFNPDRSTDKFNYTLWRGQLWNKGKLLCHVSLKSAARPFLPCKLPEKLDLEKVVSIDQLKKKISPLLFYKETYVGAKEVLRNGMYSSLYEVVEKSRSGSHLEGLLQKLEKEKLVLVKPLLDRGFLLLLSPWQMASPYDQQTGRSRMLNALFLFPEPRGVTVSAQRSVPCGTQKNSTTAILHENQIIPEFTRFIQSLHFALIQSRKDATADFNTVVEKYINEYLRRCYSGSGKYREFVLYRYESRLDDKKFLYPAPKNKSHIDSCLQNYIFSCAAYELPVSRARELMEGNRKHQQFSPISDYEATEEDSEFAIMKSGRRIHAKSEAAAVKRKFPHLGDYDPERLKDLINLIQCRKKNVGGDSDSEDLRNKSGLKRKLERQPENLPKHLKMSESSENNCQYEGGRSSEPPQTVFSIISGLGGHDTDLRHQDVSDPAVTDTHGLVKLLLETLANSGHMDSSLARSVNQALGLNSDEVEEDMRQNYEYESIPAQDQDDHELPDDAQAEPVNFKDPQSPVMLETDAACLPFAIDVDLRFPASEVGLEHTLLLKEASTGSVSSFEDYSPCPSTPVEHVYRRHHSNSNSIEVGMPWRLIPITGLKSPEEPLVYLPPKDAFPNDPRVINRQRSSDYQFPCSPFSDTQKGTAEDGLYTRQVEKLEDECELADHPFTTQHSISAIVETVILEEYSLFVKKIQEILREKNISYVSGMFTPVVLGQERIMRFSEYVCLQTSEVSVQEYVETLSEKMNSVVLSSSCIRHTPPIYCSPESAEVVHSAAPKPPPNVLPICSDSDMTLLTEPLCNSMVEDADSIEQQSSSLPVVKEEVEHVNAKAEAMLTSDQTPSSGNLMEPPEKTQKSPENLNVSSQPALSDFISQLKPEVFNSLVEIIKDVQKNTVKFYIHEEEESILCKEIKEYLTKLGNTECHPEQFLKRRAALDKLLIIIQNEDIANLIHKVPGLVTLKKLSCVSFAGVDSLDDVKNHTYNELFMSGGFVVSDESVLNPDSITTDKLKQFLQFLEDLNTPDGKWQWKVHCKMQKKLKELGRLNANALSLLTLLNTYQKKHLVEILSYHNCDSQTRNAPELECLIRLQAQSIQQRHIVFLTEKNLKPLSNYADNGIVVATVDDFMQNFTSLVGYHNSVNEEDNPSPSQERQSVHVENDGKDEEDMSLDSGDEASQIEICNDASEYDTRLETLQTETKSSRGVDAKESCVSELSPEARRSLMDKSSKIDMEEIKPITPLSTTHSAEGEKHNSVQRAPFNNFQVYSRQLNMSHQFSHFNVLTHQTFLGAAYPHSTRQNQEGGSYFPSPYSQRRDKEKSSLPGGWDKNCDSSRPYSKRK", "length": 1690, "header": "tr|A0A8V1AGA6-1|A0A8V1A626_CHICK Computationally mapped isoform of Transcription activation suppressor OS=Gallus gallus OX=9031 GN=FAM208A PE=3 SV=1 CANONICAL=A0A8V1A626-1" }, "locus": { "chromosome": "12", "start_pos": 8606105, "end_pos": 8576793, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067623.1", "url": "https://www.ensembl.org/id/ENSGALT00010067623.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041366.1", "url": "https://www.ensembl.org/id/ENSGALP00010041366.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:415999", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415999", "resource": "KEGG Pathway" }, { "id": "R-GGA-9843970", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9843970", "resource": "Reactome", "description": "Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6AIB8-1", "protein_name": "Transcription activation suppressor", "gene_name": "Tasor", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MATAAETEASSTDTSWENGGGGGGGGDDGMKPALPELESSLQNGGVFSTAELGGRGGGAGPEETAAAEAARSHGHEPLQNKSEAAAASLPKGAEEPERPFRRSFQIPRKSREKKALFQQLTPGSREFEDVLNILHSSYLEPTSVANFNYRRACLIHNELLEKEFTEKRRELKFDGRLDKELSESYAFLMVDRYQVQSICEKGLQVGQSKITVLGSPSMGIYLCRYADLLQANPLEAGAVGDVVIFKIMKGKIKSIYDPLSVKSLESMLSKSALDPTPKHECHVSKNASRITSLLAYRAYELTQYYFYEYGFDEVRRRPRHVCPYAVVSFTYKDDVQTPKFVSLRSNSFNADRNIDKFNYTLWKGQLLNKGKLLCYISLRSANRAFLPVKLPEKLDVETVMSIDCLKQKIPSSFFHKDTYVGPNEVLKNGMYCSLYEVVEKTRIGSNMECLLQKLEKEKLVLVKPLGDRGYLFLLSPFQMVSSYDHQTGKSRILHALFLFQEPRCLIVAQKSVTNTTPLEKHENLPDILKITQFLQFSLIQCRKEFKTINTINFHSVVEKYVSEFFKRGFGSGKREFFMFSYDSRLDDRKFLYSAPRNKSHIDDCLHTYIYQPEMYQLPIFKLKELFEENWRRQQFSPLSDYEGQEEELNGSKMKFGKRNNSRGETTEPGQQKSSHSLDYDKDRVKELINLIQCTKKNVGGDPDTEDTKSKNVLKRKLEDLPENMRKFAKTSNSSENYHPYEEPPQSVGLLGHDPNLRLQQEDACSTGDIHKLYNWISETLANARHSDAFLTETVNKALGLSSSGTYEELKQKCDYELNPTLDKKECEQPACTKIENVHFKDAQSPVLEVDAASGKYPPLLSSSEDPNLINVNHFEECSLCPTVSIEHGLLRQHSKSNDDEETEIHWKLIPITGGNAGSPEDQHGKHGEKHTPGMKSPGEQLVCPPPAEAFPNDPRVINRERSCDYQFPSSPATDTVKGPTEEEDTVAGQAMTVEEQCVPAAELPAVSETTESTVLGEFHLFSRKIEEILKQKNVSYVSSISTPLFSAQEKMNRLSEFIYSKTSKAGVQEFVDGLHEKLNTIIIKASAKGVNLPPGVSPNHSHTTTTLSSLGRHVVSISSSDFNSKDLFEPLCSEHLKDNSSNEQYSSSMEVEINQPHHCKELMLTSDHTVPGDTVLEPTEKEITKSPSDITISAQPALSNFISQLEPEVFNSLVKIMKDVQKNTVKFYIHEEEESVLCKEIKEYLTKLGNTECHPDQFLERRSNLDKLLIIIQNEDIAGFIHKVPGLVTLKKLPCVSFAGVDSLDDVKNHTYNELFVSGGFIVSDESVLNPEVVTIESLKNFLTFLEELSTPEGKWQWKIHCKFQKKLKELGRMNTKALSLLTLLNVYQKRHLVEILSYHSCDSQTRNAPEMDCLIRLQAQNIQQRHIVFLTEKNIKMVSNYTDNGIVVATAEDFMQNFTSLVGYHNSVTEENLPSMLGANENLESQSDAVLTLTPLELGVGISQH", "length": 1506 }, "evidence": [ { "id": "A0A8V1A626", "url": "https://omabrowser.org/oma/group/A0A8V1A626/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E7EZC0-1", "protein_name": "Protein TASOR isoform X1", "gene_name": "tasorb", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MACNFSQERKSDKESSKAGSLTLEDGDSKKQLLSASSTATSKQNGDQAGCEDEQMSEQDASERRRAGLSDLKNCGGSPSTLPRSAEELPRKNFQIPRKIKERKGLFQHLPPESREFEDVVKLLSTFYLDATSRATFNYTKASLIHNELLEKEFIEKKRELKQNGRTEAELAESYAFLLSDRNKVHFICEKGLSVGHSRINNLGNSAKGVYLSKYSDLLQMNPFEVGAAGEIILFKVMKGKVKIIENIPKNTLEPTLKYDSHVYKNASKVTSLLSYRAFEHTQQYFYEFAYDELKSRPRHVLPYAVVSFQYKGKESSIGTHSRVNSMLHEGQRVRRRYTVWSGSLVNKGEEVYQVYIRSSSLPHLPLKLPDKLDINTAMHLDQVKRKIPPVLLSWEAYSGAREVLKCGMHCSLYEVMGKSKQENSLTGLLQRLERERMVLVKPLVDKGFLFLLSSSQLFTSMERRGRSDRVLQALFIFQEQRSISKLISKNSGVEEDPLVPLEPKDAVIHQLDTFVPALHHCFYKLRANPPKELAAGVKRQALDYLSQKEQGALRPFHIAEYRHTLDDRTSQHLAPRPKNIDVVLKSYVYSPGHFQLPVEVLQQGLMDSQQAEASPPAGAEEYSPVSDWGGSDRQPSASSTTGVSQSNGGAQKQQSEYEKEKMEKLLKLIQLHKRTLGKDEGSGAEREEDWDAAGLKRRLEREGPGGVSKYLRTGLLNGEPGRVVMDSMGLCDTDLRERASQSPTLRDTQALLKLFLSTLNRMAQSSTTASNQPEMLPKNIEEHDPTESLTHCDLDLRGRRVDEEQVTQDFLEEQTACSRSSVDVYSPASNLEQQQPPRPAEAAHQIHQLWKTSTTDGVVEPCLSESEKPVQCLGKVVDTILDREFQNLCTGIHKLMEAQHIIYNSQPPLPRNEDLTIRSSPAFSPFVSKYVTPLPVQGYVKTLCEKMNHLIHSPSVSLEHVAIATPPAVVPVPAPLPPAPPPFAIPAPAQPKLPSPPAQPRTKTLSPVPKSKASSSKPQTTVKQPSSGKHRLGTVKEVHLFQPEKSADPKGTDIVETSVSELSAESSLAGTSSTVIGQIKPDVLCTLMEIMQKNAVNFYIQTGDEESELCTEIKAYLRSLGNIACNPLNYLESKSQQKFMIIIQNEDIATHVHKIPALVSLKKLPTVYFAGVDSLDDVKNRTYNELFVSGGLIVSDELILKPDNIMLAKLQAFLKFLEEQGSPWKWKVHCKTQKKLKELSRLNTEALDLLNLLTSYQKKHLVEFLPYHECDTPSRQAPDLDCLVKLQAQHTQLRHLVFLTERHDDKFSQFSGSGVIIAGMNDIMNNFQSLISIPEDVTVAVLPNPVEPDAVRDEEDMSIDSEDDMPVSDTNIQTEKDLTEPHAPQPPPPQTDGFRPPLPNQPSLDPIMDPLVLPNPSMCPSQGSFSDYAALKSAIALYKAASQESASRPEVEDTLTSFGVNPHQSYLCPSSSQWSPYSGSPAYHMSSAYSSPVQVASRGSDYSQSVAPPGVPPPANTLTLPIGQPLPIPPSFPQPPVSLVEVLPPVPESVSSLQPPGHIADSVGVPGVEMAITANKQGHPGSQTIKKDVETPSSSSTFSSSSIRTTFPSYPESTLFPALTPIPPVPPLYNWGPTPGGQHSFTAGQSGAGFSALPSTQSEAAKPTDGSWIGATESGTSQEQEEEKAMTSSTSKVGQQEGIGEKDSALASSSSCSQGSRTPVNSSSESQGGSQAPPARGGISSRGLLPLPGAPMGAMCRGGHNNSMYNPRGGPPDMMRGGFRGRGVPPHPMRSRPGRGHIRGGPSCNWGYPPGRGGGGRSDYYSDYTYN", "length": 1827 }, "evidence": [ { "id": "A0A8V1A626", "url": "https://omabrowser.org/oma/group/A0A8V1A626/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q69ZR9-1", "protein_name": "Protein TASOR", "gene_name": "Tasor", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MATAAETEAPSTDASWKSRGGGGGDDGMKPALPELESSLQNGGGDGGGGAGPEETAAAEAARSYGHEQPQQTSEAAAAALPKGAEEPERPFRRSFQIPRKSREKKALFQPLTPGSREFEDVLNILHSSYLEPSSVTYFNYRRACLIHNELLEKEFTEKRRELKFDGRLDKELSESYAFLMVDRYQVQSICEKGLQVGQSKITVLGSPSMGIYLCRYADLLQANPLEAGAVGDVVIFKIMKGKIKSIYDPLSVKSLESMLSKNALDPTPKHECHVSKNASRITSLLAYRAYELTQYYFYEYGFDEVRRRPRHVCPYAVVSFTYKDDVQTPKFLSPLRSNSFNADRNIDKFNYTLWKGQLLNKGKLLCYISLRSANRAFLPVKLPEKLDVETVMSIDCLKQKIPPSFFYKDTYVGPNEVLKNGMYCSLYEVVEKTRIGSNMECLLQKLEKEKLVLVKPLGDRGYLFLLSPFQMVSPYEHQTVKSRILHALFLFQEPRCLIITQKGIMNTTPLEKPENLADILKITQFLQFSLIQCRKEFKTINTINFHSVVEKYVSEFFKRGFGSGKREFFMFSYDSRLDDRKFLYSAPRNKSHIDDCLHTYIYQPEMYQLSIFKLKELFEENWRRQQFSPLSDYEGQEEELNGSKMKFGKRNNSRDETTEPEQQKSSHSLDYDKDRVKELINLIQCTKKNVGGDPDPEDTKSKNVLKRKLEDLPENMRKFAKTSNSTESCHLYEESPQSIGLLGQDPNLRVQQEDSGNTGDIHKLYNWLSEALANARHSDGFLTETVNKALGLSSSGAYEELKQKCDYELNSTLDKKESEQPACTKIENVHFKDAQSPLLEVDAASVKYPPLLSSSEVGINHKLHCKEDPNLINVNNFEGCSLCPTVSIEHGFLRQHSKSNDDEETEIHWKLIPITGGNAGSPEDQHGKHGEKQTPDTLKGTTEEDTVTAGQAMAVEEQCVPAAELPRVSEITENTVLGEFHLFSRKVEEILKEKNVSYVSAISTPIFSAQEKMNRLSEFIHSNTSKAGVEEFVDGLHEKLNTVVITASAKGVSLPPAVSANHSHAAAALASLGRRVVSISSSDFSAKELFEPLCSEHLKDNNSNEQYSSSVEVEMNRPHHCKELMLTSDHTVPGDTVLEPTEKEITKSPSDITISAQPALSNFISQLEPEVFNSLVKIMKDVQKNTVKFYIHEEEESVLCKEIKEYLTKLGNTECHPDQFLERRSNLDKLLIIIQNEDIAGFIHKVPGLVTLKKLPCVSFAGVDSLDDVKNHTYNELFVSGGFIVSDESILNLEVVTIESLKIFLTFLEELSTPEGKWQWKIHCKFQKKLKELGRMNTKALSLLTLLNVYQKKHLVEILSYHSCDSQTRNAPEMDCLIRLQAQNIQQRHIVFLTEKNIKMVSSYTDNGIVVATTEDFMQNFTSLVGYHNSVTEESLPPLLGANENLESQSALLENDEKDEEDMSLDSGDEISHIEVFSNVHSEILAGETKGSSGTDQKKNIQIELQSSLDVQNSLLEDKTYLIDCEASAPIDRVCSEGESSNSAEQDAYSDFQADQNQLQMSHQCSHFNVLTHQTFLGTPYALSSTRSQENENYFLSAYKNSGTEKSPLS", "length": 1610 }, "evidence": [ { "id": "A0A8V1A626", "url": "https://omabrowser.org/oma/group/A0A8V1A626/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9UK61-1", "protein_name": "Protein TASOR", "gene_name": "TASOR", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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"length": 1670 }, "evidence": [ { "id": "A0A8V1A626", "url": "https://omabrowser.org/oma/group/A0A8V1A626/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "mesodermal to mesenchymal transition involved in gastrulation", "id": "GO:0060809", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060809", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A626", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A626" } ], "pmid": "" }, { "name": "negative regulation of gene expression, epigenetic", "id": "GO:0045814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045814", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A626", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A626" } ], "pmid": "" }, { "name": "anterior/posterior axis specification, embryo", "id": "GO:0008595", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008595", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A626", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A626" } ], "pmid": "" }, { "name": "protein localization to heterochromatin", "id": "GO:0097355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097355", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A626", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A626" } ], "pmid": "" }, { "name": "transposable element silencing by heterochromatin formation", "id": "GO:0141005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0141005", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A626", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A626" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A626", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A626" } ], "pmid": "" }, { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A626", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A626" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A626", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A626" } ], "pmid": "" }, { "name": "heterochromatin", "id": "GO:0000792", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000792", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A626", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A626" } ], "pmid": "" }, { "name": "HUSH complex", "id": "GO:0140283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140283", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A626", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A626" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1073, "end_pos": 1075, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1233, "end_pos": 1235, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1351, "end_pos": 1353, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1500, "end_pos": 1502, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1641, "end_pos": 1643, "annotation": "n_glycosylation_sequon" }, { "start_pos": 367, "end_pos": 369, "annotation": "n_glycosylation_sequon" }, { "start_pos": 529, "end_pos": 531, "annotation": "n_glycosylation_sequon" }, { "start_pos": 612, "end_pos": 614, "annotation": "n_glycosylation_sequon" }, { "start_pos": 723, "end_pos": 725, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1A626", "database": 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"publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A638-1", "uniprot_ac": "A0A8V1A638", "uniprot_id": "A0A8V1A638_CHICK", "mass": { "chemical_mass": 59617.0, "monoisotopic_mass": 59617.0 }, "refseq": {}, "gene_names": [ { "name": "DENND2D", "type": "recommended", "evidence": [ { "id": "A0A8V1A638", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A638" } ] } ], "protein_names": [ { "name": "DENN domain containing 2D", "type": "synonym", "evidence": [ { "id": "A0A8V1A638", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A638/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A638", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A638" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "DENND2D", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A638", "locus": { "chromosome": "26", "start_pos": 1075689, "end_pos": 1066440, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010024608", "url": "https://www.ensembl.org/id/ENSGALG00010024608" } ] } } ], "crossref": [ { "id": "A0A8V1A638", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A638", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR001194", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001194", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005112", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005112", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005113", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005113", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037516", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037516", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043153", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043153", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051942", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051942", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A638", "url": "https://www.orthodb.org/?gene=A0A8V1A638", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A642", "url": "https://www.orthodb.org/?gene=A0A8V1A642", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15288", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15288", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15288:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15288:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02141", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02141", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03455", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03455", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03456", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03456", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-8876198", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8876198", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1A638", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A638", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A638-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A638-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A642", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A642", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A642-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A642-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPSPQSPSDARCGPPPPLLLSSLLSSSPLRPVPSLLPRESESAAGGSGAPRSAAPGPLHVGATMASSISNLFRRSLRRSGRREGKQEAPAADGIPSHVPLGKAGERSSILYSAGQFFFEYLVVVSLRKMSDGRYEPKIAYQFPKRENLLKGQKEEEERLLQAIPLFCFPDGNNWEPVTTFPSETFSFVLTNVDGSRKIGYCRRLLPSGRGVRLPEVFCIISCLGCFGLFSKILDEVEKRRQISMAVIYPFMQGLRESPFPAPGKTVTIKSFIPESGTELIELTRPVDAHLEHVEFPALLQRLSPILILHIFASAVLERRLIFLAEELSVLSQCIHAVAALLYPFTWAHTYIPVVPECLLDTVCCPTPFMVGIQRRHLERVLEQPMEEALIVDLCEGKILRAVGDEDQILPIKLQNEMLASLNRHNSNNNIHTSEQLNALISEAFVQFFVRLVGHYTSHIKWSKNGPGTFQERAFCKAITSKTNRRFVKKFVKTNMFSLFIEDAEKSRIPQEAYFQQKITEYQQQKKHRRDS", "length": 531, "header": "tr|A0A8V1A638-1|A0A8V1A638_CHICK Isoform 1 of DENN domain containing 2D OS=Gallus gallus OX=9031 GN=DENND2D PE=4 SV=1 CANONICAL=A0A8V1A638-1" }, "isoforms": [ { 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"url": "https://www.uniprot.org/uniprotkb/A0A8V1A638" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A638", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A638" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A638", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A638" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1A638", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A638" }, { "id": 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"https://www.uniprot.org/uniprotkb/A0A8V1A643" } ] } ], "protein_names": [ { "name": "MORN repeat-containing protein 5", "type": "recommended", "evidence": [ { "id": "A0A8V1A643", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A643/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A643", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A643" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MORN5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A643", "locus": { "chromosome": "17", "start_pos": 9316565, "end_pos": 9314472, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027904", "url": "https://www.ensembl.org/id/ENSGALG00010027904" } ] } } ], "crossref": [ { "id": "A0A8V1A643", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A643", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR003409", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003409", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042814", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042814", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A643", "url": "https://www.orthodb.org/?gene=A0A8V1A643", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46437", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46437", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46437:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46437:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02493", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02493", 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"MEVTGSRFCGSTERGRMEGWGSYTLPTGTEYLGELRDGAFHGRGALLFPGGGTFRAVWHRGVPAEGKFTFADGLEYAAERWDYCDGYDRRFYTEICSGLRPAGISQLTNLDPPRKIPEGCYDCGDGFYNPNTRTVTDYELRFLRNAGKPSVSSVMS", "length": 156, "header": "tr|A0A8V1A643-1|A0A8V1A643_CHICK Isoform 1 of MORN repeat-containing protein 5 OS=Gallus gallus OX=9031 GN=MORN5 PE=4 SV=1 CANONICAL=A0A8V1A643-1" }, "locus": { "chromosome": "17", "start_pos": 9315841, "end_pos": 9314535, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067640.1", "url": "https://www.ensembl.org/id/ENSGALT00010067640.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041383.1", "url": "https://www.ensembl.org/id/ENSGALP00010041383.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "sperm flagellum", "id": "GO:0036126", "url": 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"n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A650-1", "uniprot_ac": "A0A8V1A650", "uniprot_id": "A0A8V1A650_CHICK", "mass": { "chemical_mass": 48675.0, "monoisotopic_mass": 48675.0 }, "refseq": { "ac": "XP_418047", "name": "bystin", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418047" }, "gene_names": [ { "name": "BYSL", "type": "recommended", "evidence": [ { "id": "A0A8V1A650", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A650" } ] }, { "name": "BYSL", "type": "synonym", "evidence": [ { "id": "XP_418047", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418047" } ] } ], "protein_names": [ { "name": "Bystin like", "type": "synonym", "evidence": [ { "id": "A0A8V1A650", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A650/entry#names_and_taxonomy" } ] }, { "name": "bystin", "type": "synonym", "evidence": [ { "id": "XP_418047", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418047" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052557.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_418047.3. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_418047", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418047" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A650", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A650" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "BYSL", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A650", "locus": { "chromosome": "26", "start_pos": 5071730, "end_pos": 5067550, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010026568", "url": "https://www.ensembl.org/id/ENSGALG00010026568" } ] } } ], "crossref": [ { "id": "A0A8V1A650", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A650", "database": "AlphaFoldDB", "categories": [] }, { "id": "419927", "url": "https://www.ncbi.nlm.nih.gov/gene/419927", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007955", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007955", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:419927", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419927", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TKLPVIW", "url": "https://omabrowser.org/oma/group/TKLPVIW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A650", "url": "https://www.orthodb.org/?gene=A0A8V1A650", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12821", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12821", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12821:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12821:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05291", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05291", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_418047", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418047", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1A650", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A650", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A650-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A650-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPKAARGAEPLHEQILRAAAPRVRHRRGREEGDDAEERDGGYVGPRLARRILREARKQQEELEAEHGPGAPARPPQRCAAPGGPDSEEDEEDEEWPSLQRAAEWDGRCGGGDVEVDPEDEKALEVFMSRAPPLRRTLADVIMEKITEKQTEVQTALSELSGRPMPQLDPRVLEVYRGVREVLSKYRSGKLPKAFKIIPALSNWEQILYITEPETWTAAAMYQATRIFSSNLKERMAQRFYNLVLLPRVRDDIAEYKRLNFHLYMALKKALFKPGAWFKGILIPLCESGTCTLREAIIIGSILTKCSIPVLHSSAAMLKIAEMPYNGANSIFLRLLIDKKYALPFRVVDALVFHFLAFRTDQRTLPVLWHQSFLALCQRYKEDLSSEQKEALLELLKFHSHPQISAEIRRELANSKTRDVEGQEPAAME", "length": 428, "header": "tr|A0A8V1A650-1|A0A8V1A650_CHICK Isoform 1 of Bystin like OS=Gallus gallus OX=9031 GN=BYSL PE=1 SV=1 CANONICAL=A0A8V1A650-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A650-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A650/entry#A0A8V1A650-1", "sequence": { "sequence": "MPKAARGAEPLHEQILRAAAPRVRHRRGREEGDDAEERDGGYVGPRLARRILREARKQQEELEAEHGPGAPARPPQRCAAPGGPDSEEDEEDEEWPSLQRAAEWDGRCGGGDVEVDPEDEKALEVFMSRAPPLRRTLADVIMEKITEKQTEVQTALSELSGRPMPQLDPRVLEVYRGVREVLSKYRSGKLPKAFKIIPALSNWEQILYITEPETWTAAAMYQATRIFSSNLKERMAQRFYNLVLLPRVRDDIAEYKRLNFHLYMALKKALFKPGAWFKGILIPLCESGTCTLREAIIIGSILTKCSIPVLHSSAAMLKIAEMPYNGANSIFLRLLIDKKYALPFRVVDALVFHFLAFRTDQRTLPVLWHQSFLALCQRYKEDLSSEQKEALLELLKFHSHPQISAEIRRELANSKTRDVEGQEPAAME", "length": 428, "header": "tr|A0A8V1A650-1|A0A8V1A650_CHICK Isoform 1 of Bystin like OS=Gallus gallus OX=9031 GN=BYSL PE=1 SV=1 CANONICAL=A0A8V1A650-1" }, "locus": { "chromosome": "26", "start_pos": 5070135, "end_pos": 5067749, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010064540.1", "url": "https://www.ensembl.org/id/ENSGALT00010064540.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039559.1", "url": "https://www.ensembl.org/id/ENSGALP00010039559.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:419927", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419927", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "I3LH38-1", "protein_name": "Bystin like", "gene_name": "BYSL", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPKLKAARGAEGQEKHAPLADQILAGNAVRAGTREKRRGRGTGEEEEEYVGPRLTRRILQQARQQQEELEAEHGTGDRPAAPQDRTTRLGPGAPQDGSDDEEWPTLAKAATMTGPGYQAEVVIDPEDERAIELFMNKNPPARRTLADIIMEKLTEKKTEVESVMSEVSGLPLPRLNPRLLEVYRGVREVLSKYRSGKLPTAFKMIPALSNWEEILYVTEPEAWSAAAMYQATRIFASNLKEHKAQRFYNLVLLPRVRDDIAEYKRLNFHLYMALKKALFKPGAWFKGILLPLCESGTCTLREAIILGSIITKCSIPVLHSSAAMLKIAEMEYSGANSIFLRLLLDKKYALPYRVLDALVFHFLRFRTEKRELPVLWHQCLLTLVQRYKADLATEQKEALLELLRVQSHPQLSPEIRRELQSAVPRDVEDVPVTME", "length": 435 }, "evidence": [ { "id": "A0A8V1A650", "url": "https://omabrowser.org/oma/group/A0A8V1A650/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O54825-1", "protein_name": "Bystin", "gene_name": "Bysl", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKFKVTRGASNREKHAPLAEQILAGNAVRAGTREKRRGREVEEEEEYVGPRLSRRILQQARQQQEELETDHGAGDRSAPPRERATRLGPGLPQDGSDEEDEEWPTLEKAAKMAGVDHQAEVIVDPEDERAIEMFMNKNPPVRRTLADIIMEKLTEKQTEVETVMSEVSGFPMPQLDPRVLEVYRGVREVLCKYRSGKLPKAFKVIPALSNWEQILYVTEPEAWTAAAMYQATRIFASNLKERMAQRFYNLVLLPRVRDDIAEYKRLNFHLYMALKKALFKPGAWFKGILIPLCESGTCTLREAIIVGSIITKCSIPVLHSSAAMLKIAEMEYSGANSIFLRLLLDKKYALPYRVLDALVFHFLAFRTEKRQLPVLWHQCLLTLAQRYKADLATEQKEALLELLRLQPHPQLSPEIRRELQSAVPRDVEDGGVTME", "length": 436 }, "evidence": [ { "id": "A0A8V1A650", "url": "https://omabrowser.org/oma/group/A0A8V1A650/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P38333-1", "protein_name": "Essential nuclear protein 1", "gene_name": "ENP1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MARASSTKARKQRHDPLLKDLDAAQGTLKKINKKKLAQNDAANHDAANEEDGYIDSKASRKILQLAKEQQDEIEGEELAESERNKQFEARFTTMSYDDEDEDEDEDEEAFGEDISDFEPEGDYKEEEEIVEIDEEDAAMFEQYFKKSDDFNSLSGSYNLADKIMASIREKESQVEDMQDDEPLANEQNTSRGNISSGLKSGEGVALPEKVIKAYTTVGSILKTWTHGKLPKLFKVIPSLRNWQDVIYVTNPEEWSPHVVYEATKLFVSNLTAKESQKFINLILLERFRDNIETSEDHSLNYHIYRAVKKSLYKPSAFFKGFLFPLVETGCNVREATIAGSVLAKVSVPALHSSAALSYLLRLPFSPPTTVFIKILLDKKYALPYQTVDDCVYYFMRFRILDDGSNGEDATRVLPVIWHKAFLTFAQRYKNDITQDQRDFLLETVRQRGHKDIGPEIRRELLAGASREFVDPQEANDDLMIDVN", "length": 483 }, "evidence": [ { "id": "A0A8V1A650", "url": "https://omabrowser.org/oma/group/A0A8V1A650/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P51406-1", "protein_name": "Bystin", "gene_name": "bys", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MGKPKKANVATIKNVNLEKQITEGRVAKNKNKDKVKLRAEESANIDARSSQKILAAAKLQQLELDEENFPSLVTVKKVNFSLNDGHVKEDEEVNETDLMADLDMDEDDVAAFERFQQPAQEGKRTLHLSKMIMQKIQEKEADIHTKISDEGSLKIEEIDPKVKEMYEGVRDVLKRYRSGKIPKAFKIIPKLRNWEQILFITEPHNWSAAAMFQGTRIFCSVLSQAMAQRFYNLVLLPRVRDDLCEYKKLNMHLYNALKRALFKPAAFMKGIILPLLEGGDCTLREAIIFGSVVARSSIPVLHSSACLLKICEMAYSGANSIFIRYFLDKRYALPYRVVDAAVFHFLRFENDKRELPVLWHQSLLTFAQRYKNDISSEQRDALLQLLKKKSHFKITPDVRRELQAASCRDVEMMETDNGLAGQPAKMYTDADVEYEG", "length": 436 }, "evidence": [ { "id": "A0A8V1A650", "url": "https://omabrowser.org/oma/group/A0A8V1A650/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q13895-1", "protein_name": "Bystin", "gene_name": "BYSL", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPKFKAARGVGGQEKHAPLADQILAGNAVRAGVREKRRGRGTGEAEEEYVGPRLSRRILQQARQQQEELEAEHGTGDKPAAPRERTTRLGPRMPQDGSDDEDEEWPTLEKAATMTAAGHHAEVVVDPEDERAIEMFMNKNPPARRTLADIIMEKLTEKQTEVETVMSEVSGFPMPQLDPRVLEVYRGVREVLSKYRSGKLPKAFKIIPALSNWEQILYVTEPEAWTAAAMYQATRIFASNLKERMAQRFYNLVLLPRVRDDVAEYKRLNFHLYMALKKALFKPGAWFKGILIPLCESGTCTLREAIIVGSIITKCSIPVLHSSAAMLKIAEMEYSGANSIFLRLLLDKKYALPYRVLDALVFHFLGFRTEKRELPVLWHQCLLTLVQRYKADLATDQKEALLELLRLQPHPQLSPEIRRELQSAVPRDVEDVPITVE", "length": 437 }, "evidence": [ { "id": "A0A8V1A650", "url": "https://omabrowser.org/oma/group/A0A8V1A650/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q54IS0-1", "protein_name": "Bystin", "gene_name": "bysl", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGKDVKKVHKLRHDPLSKQIEESESAYQKPHKRVGKLRKKKAEMENDTGIDETESVIPSALSKKILDQIREQAIEVEVEDRKKEKQEKLLTFEQERIQSKLLSFNDFIDDDDDDEDADQDDNKRRSNGNDFDENDGFEQFSDTESQFGVGGEVEIDEEDERVLSMFMGGGGGDGQEQQFQTRFTLGDIIESKLKEHESRQVSSENAINPKVIDVYTKVGKLLETYTSGKIPRAFRILPNFTNWEDLLYLTRPDKWTPHSIRVATKLFCMSTNSKITQRFLSIVVLPRVRDNIAEYKKLNYHLYMALKKSLYRPAAFYKAILLPLAESGDCTLLEAKIIGSVVCKVSIPVLHSSVALMKLSQLTRYNGATSMFIRMLCDKKYALPYRVIDGLVDHFVMFDEEVRELPVLWHRALLSFVQRYKTDITKDQKEKLKIILRKHNHHIITAEIRRELFFSNSRGGVAPSNFTDDTSSMME", "length": 475 }, "evidence": [ { "id": "A0A8V1A650", "url": "https://omabrowser.org/oma/group/A0A8V1A650/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q5E9N0-1", "protein_name": "Bystin", "gene_name": "BYSL", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPKFKAARGAGVQEKHAPLAEQILAGDAVRAGTREKRRGRGTGDEEEEYVGPRLTRRILQQARQQQEELEAEHGSGDRPAVPRERTTRLGPGVPQDGSDDEEWPTLEQAAARAGPGYQAEVVVDPEDERAIEMFMNQNPPARRTLADIIMEKLTEKQTEVETVMSEVSGFPVPQLDPRVLEVYRGVREVLSKYRSGKLPKAFKIIPALSNWEQILYITEPEAWTAAAMYQATRIFASNLKERMAQRFYNLVLLPRVRDDIAEYKRLNFHLYMALKKALFKPGAWFKGILIPLCESGTCTLREAIIVGSIITKCSIPVLHSSAAMLKIAEMEYSGANSIFLRLLLDKKYALPYRVLDALVFHFLGFRTEKRELPVLWHQCLLTLVQRYKADLATEQKEALLELLRLQPHPQLSPEIRRELQSAVPRDVEDVPVTME", "length": 435 }, "evidence": [ { "id": "A0A8V1A650", "url": "https://omabrowser.org/oma/group/A0A8V1A650/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q80WL2-1", "protein_name": "Bystin", "gene_name": "Bysl", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPKLKVTRGARNQERHAPLAEQILAGDAVRAGTREKRRRHGVEEEEEYVGPRLSRRILQQARQQQEELETEHATGDRPAKPRERATRLGPGVPQDGSDEEDEEWPTLEKAAKMTVVNHQAEVVVDPEDERAIEMFMNKNPPVRRTLADIIMEKLTEKQTEVETVMSEVSGFPMPQLDPRVLEVYRGVREVLCKYRSGILPKAFKIIPALSNWEQILYVTEPEAWTAAAMYQATRIFASNLKERMAQRFYNLVLLPRVRDDIAEYKRLNFHLYMALKKALFKPGAWFKGILIPLCESGTCTLREAIIVGSIISKCSIPVLHSSAAMLKIAEMEYSGASSIFLRLLLDKKYALPYRVLDALVFHFLAFRTEKRQLPVLWHQCLLTLAQRYKADLATEQKEALLELLRLQPHPQLSPEIRRELQSAVPRDVEDVVVTME", "length": 436 }, "evidence": [ { "id": "A0A8V1A650", "url": "https://omabrowser.org/oma/group/A0A8V1A650/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8RWS4-1", "protein_name": "Bystin", "gene_name": "ENP1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAKKRDRIVNTQPFISDDASVASSRKRSKVPKTHQKQEKLIEAGMSEKIMKQALAQQKEVADEENAERNPSSAAFAVAGAATAGEEQKILEEEEDDIDDFDGTFENQSQFDKQEEINEDDEKLFESFLNKNAPPQRTLTDIIIKKLKDKDADLAEEERPDPKMDPAITKLYKGVGKFMSEYTVGKLPKAFKLVTSMEHWEDVLYLTEPEKWSPNALYQATRIFASNLKDRQVQRFYNYVLLPRVREDIRKHKKLHFALYQALKKSLYKPSAFNQGILFPLCKSGTCNLREAVIIGSILEKCSIPMLHSCVALNRLAEMDYCGTTSYFIKVLLEKKYCMPYRVLDALVAHFMRFVDDIRVMPVIWHQSLLTFVQRYKYEILKEDKEHLQTLLQRQKHHLVTPEILRELKDSRNRGEKEDPMVDNFAPVPAKEDRFDIPEVPMEED", "length": 444 }, "evidence": [ { "id": "A0A8V1A650", "url": "https://omabrowser.org/oma/group/A0A8V1A650/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A650", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A650" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A650", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A650" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A650", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A650" } ], "pmid": "" }, { "name": "apical part of cell", "id": "GO:0045177", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045177", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A650", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A650" } ], "pmid": "" }, { "name": "chromosome", "id": "GO:0005694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005694", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A650", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A650" } ], "pmid": "" }, { "name": "preribosome, small subunit precursor", "id": "GO:0030688", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030688", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A650", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A650" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "snoRNA binding", "id": "GO:0030515", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030515", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A650", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A650" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "rRNA processing", "id": "GO:0006364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006364", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A650", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A650" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { 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"sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A662-1", "uniprot_ac": "A0A8V1A662", "uniprot_id": "A0A8V1A662_CHICK", "mass": { "chemical_mass": 42592.0, "monoisotopic_mass": 42592.0 }, "refseq": { "ac": "XP_015153997", "name": "pygopus homolog 2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015153997" }, "gene_names": [ { "name": "PYGO2", "type": "recommended", "evidence": [ { "id": "A0A8V1A662", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A662" } ] }, { "name": "PYGO2", "type": "synonym", "evidence": [ { "id": "XP_015153997", 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This record is derived from a genomic sequence (NC_052556.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 17, 2018 this sequence version replaced XP_015153997.1. 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"https://www.uniprot.org/uniprotkb/A0A8V1A666", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A666-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A666-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGE0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGE0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGE0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGE0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAGGSGPGGLSSSCPQPPPPPPGNGAACAAADGTPASPPGLTYNQCGANNPAAAAGGAGGGGGGPGVGAAPAGGPGGGLQREPVYNWQATKPTVQERFAFLFNNEVLSDVHFLVGKGRGTQRIPAHRFVLAVGSAVFDAMFNGGMATTSTEIELPDVEPAAFLALLKFLYSDEVQIGPETVMTTLYTAKKYAVPALEAHCVEFLKKNLRADNAFMLLTQARLFDEPQLASLCLENIDKNTSDAINAEGFTDIDLDTLVAVLERDTLGIREVRLFGAVVRWSEAECQRQQLQVVPENKRKVLGKALALIRFPLMTIEEFAAGPAQSGILTDREVVSLFLHFTVNPKPRVEFIDRPRCCLRGKECSISRFQQVLSEQTDLRRWLWVVRLHTRTHGLPGPRFPLRHQRAAQGDPRIAHQRRQDLLHLLLRGREQQRHFGGGRTDPRDHLLHIVPPRVGARQRPEAPPRSPPPRGCGRPFLPSPHRHPPVAALSVGASPPAGSTEIREELPQVIVVRLLKEVQAPHVAQVCGHLLCGDRGGRWGRGVAVWGRVWGHAERPHLGSSHTAPPPAWLVWCPRSSDTSP", "length": 582, "header": "tr|A0A8V1A666-1|A0A8V1A666_CHICK Isoform 1 of BTB domain containing 2 OS=Gallus gallus OX=9031 GN=BTBD2 PE=4 SV=1 CANONICAL=A0A8V1A666-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A666-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A666/entry#A0A8V1A666-1", "sequence": { "sequence": "MAAGGSGPGGLSSSCPQPPPPPPGNGAACAAADGTPASPPGLTYNQCGANNPAAAAGGAGGGGGGPGVGAAPAGGPGGGLQREPVYNWQATKPTVQERFAFLFNNEVLSDVHFLVGKGRGTQRIPAHRFVLAVGSAVFDAMFNGGMATTSTEIELPDVEPAAFLALLKFLYSDEVQIGPETVMTTLYTAKKYAVPALEAHCVEFLKKNLRADNAFMLLTQARLFDEPQLASLCLENIDKNTSDAINAEGFTDIDLDTLVAVLERDTLGIREVRLFGAVVRWSEAECQRQQLQVVPENKRKVLGKALALIRFPLMTIEEFAAGPAQSGILTDREVVSLFLHFTVNPKPRVEFIDRPRCCLRGKECSISRFQQVLSEQTDLRRWLWVVRLHTRTHGLPGPRFPLRHQRAAQGDPRIAHQRRQDLLHLLLRGREQQRHFGGGRTDPRDHLLHIVPPRVGARQRPEAPPRSPPPRGCGRPFLPSPHRHPPVAALSVGASPPAGSTEIREELPQVIVVRLLKEVQAPHVAQVCGHLLCGDRGGRWGRGVAVWGRVWGHAERPHLGSSHTAPPPAWLVWCPRSSDTSP", "length": 582, "header": "tr|A0A8V1A666-1|A0A8V1A666_CHICK Isoform 1 of BTB domain containing 2 OS=Gallus gallus OX=9031 GN=BTBD2 PE=4 SV=1 CANONICAL=A0A8V1A666-1" }, "locus": { "chromosome": "28", "start_pos": 2585982, "end_pos": 2568908, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067666.1", "url": "https://www.ensembl.org/id/ENSGALT00010067666.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041409.1", "url": "https://www.ensembl.org/id/ENSGALP00010041409.1" } ] } }, { "isoform_ac": "A0A8V1AGE0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A666/entry#A0A8V1AGE0-1", "sequence": { "sequence": "MPRCCPALCIAPRPTTTAAPTPAASSPLPLPPAAVSRPPLVVLLLLQRRPAPRRAPHKMAAGGSGPGGLSSSCPQPPPPPPGNGAACAAADGTPASPPGLTYNQCGANNPAAAAGGAGGGGGGPGVGAAPAGGPGGGLQREPVYNWQATKPTVQERFAFLFNNEVLSDVHFLVGKGRGTQRIPAHRFVLAVGSAVFDAMFNGGMATTSTEIELPDVEPAAFLALLKFLYSDEVQIGPETVMTTLYTAKKYAVPALEAHCVEFLKKNLRADNAFMLLTQARLFDEPQLASLCLENIDKNTSDAINAEGFTDIDLDTLVAVLERDTLGIREVRLFGAVVRWSEAECQRQQLQVVPENKRKVLGKALALIRFPLMTIEEFAAGPAQSGILTDREVVSLFLHFTVNPKPRVEFIDRPRCCLRGKECSISRFQQVESRWGYSGTSDRIRFSVNKRIFVVGFGLYGSIHGPTDYQVNIQIIHTDSNTVLGQNDTGFSCDGSSNTFRVMFKEPVEVLPNVNYTACATLKGPDSHYGTKGLRKVIHESPTSGAKTCFTFCYAAGNNNGTSVEDGQIPEIIFYT", "length": 575, "header": "tr|A0A8V1AGE0-1|A0A8V1A666_CHICK Computationally mapped isoform of BTB domain containing 2 OS=Gallus gallus OX=9031 GN=BTBD2 PE=4 SV=1 CANONICAL=A0A8V1A666-1" }, "locus": { "chromosome": "28", "start_pos": 2580796, "end_pos": 2568734, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067664.1", "url": "https://www.ensembl.org/id/ENSGALT00010067664.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041407.1", "url": "https://www.ensembl.org/id/ENSGALP00010041407.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 35, "start_aa": "Thr", "end_pos": 35, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr35", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:420080", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420080", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1M311-1", "protein_name": "BTB domain containing 2", "gene_name": "Btbd2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAGGSGRASCPPGVGPGAGGLGPSANAAAAPSNAAACASGPPPPPSPPPGPGTDAQAVGEERDDAGPGALLREPVYNWQATKPTVQERFAFLFNNEVLCDVHFLVGKGLSSQRVPAHRFVLAVGSAVFDAMFNGGMATTSTEIELPDVEPAAFLALLKFLYSDEVQIGPETVMTTLYTAKKYAVPALEAHCVEFLKKHLRADNAFMLLTQARLFDEPQLASLCLESIDKNTADAIAAEGFTDIDLDTLVAVLERDTLGIREVRLFNAVVRWSEAECQRQQLQVTPENKRKVLGKALGLIRFPLMTIEEFAAGPAQSGILVDREVVSLFLHFTVNPKPRVEFIDRPRCCLRGKECSINRFQQVESRWGYSGTSDRISSRLLHGRASWAQDIVPSAARCLRRFSVNKRIFVVGFGLYGSIHGPTDYQVNIQIIHTDSNTVLGQNDTGFSCDGSASTFRVMFKEPVEVLPNVNYTACATLKGPDSHYGTKGLRKVTHESPTTGAKTCFTFCYAAGNNNGTSVEDGQIPEIIFYT", "length": 532 }, "evidence": [ { "id": "A0A8V1A666", "url": "https://omabrowser.org/oma/group/A0A8V1A666/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1SDH6-1", "protein_name": "BTB domain containing 2", "gene_name": "BTBD2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAAGGSGGRASCPPGVGPGAGGGPGPSANAAPAPGNAAAAAAAPAPAAPGPPPPVSGPGAQAAAGGERAAEEPGAAALLREPVYNWQATKPTVKERFAFLFNNEVLCDVHFLVGKGLGAQRIPAHRFVLAVGSAVFDAMFNGGMATTSTEIELPDVEPAAFLALLKFLYSDEVQIGPETVMTTLYTAKKYAVPALEAHCVEFLKKNLRADNAFMLLTQARLFDEPQLASLCLENIDKNTADAITAEGFTDIDLDTLVAVLERDTLGIREVRLFNAVVRWSEAECQRQQLQVTPENKRKVLGKALALIRFPLMTIEEFAAGPAQSGILVDREVVSLFLHFTVNPKPRVDFIDRPRCCLRGKECSINRFQQVESRWGYSGTSDRIRFSVNKRIFVVGFGLYGSIHGPTDYQVNIQIIHTDSNTVLGQNDTGFSCDGSASTFRVMFKEPVEVLPNVNYTACATLKGPDSHYGTKGLRKVTHESPTTGAKTCFTFCYAAGNNNGTSVEDGQIPEVIFYT", "length": 515 }, "evidence": [ { "id": "A0A8V1A666", "url": "https://omabrowser.org/oma/group/A0A8V1A666/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q9BX70-1", "protein_name": "BTB/POZ domain-containing protein 2", "gene_name": "BTBD2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAGGSGGRASCPPGVGVGPGTGGSPGPSANAAATPAPGNAAAAAAAAAAAAAAPGPTPPAPPGPGTDAQAAGAERAEEAAGPGAAALQREAAYNWQASKPTVQERFAFLFNNEVLCDVHFLVGKGLSSQRIPAHRFVLAVGSAVFDAMFNGGMATTSTEIELPDVEPAAFLALLKFLYSDEVQIGPETVMTTLYTAKKYAVPALEAHCVEFLKKNLRADNAFMLLTQARLFDEPQLASLCLENIDKNTADAITAEGFTDIDLDTLVAVLERDTLGIREVRLFNAVVRWSEAECQRQQLQVTPENRRKVLGKALGLIRFPLMTIEEFAAGPAQSGILVDREVVSLFLHFTVNPKPRVEFIDRPRCCLRGKECSINRFQQVESRWGYSGTSDRIRFSVNKRIFVVGFGLYGSIHGPTDYQVNIQIIHTDSNTVLGQNDTGFSCDGSASTFRVMFKEPVEVLPNVNYTACATLKGPDSHYGTKGLRKVTHESPTTGAKTCFTFCYAAGNNNGTSVEDGQIPEVIFYT", "length": 525 }, "evidence": [ { "id": "A0A8V1A666", "url": "https://omabrowser.org/oma/group/A0A8V1A666/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A666", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A666" } ], "pmid": "" }, { "name": "P-body", "id": "GO:0000932", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000932", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A666", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A666" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "neurogenesis", "id": "GO:0022008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022008", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A666", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A666" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 240, "end_pos": 242, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1A666", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A666" }, { "id": "PS50097", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50097" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BTB", "eco_id": "ECO_0000259", "start_pos": 109, "end_pos": 179, "start_aa": "Ser", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 35 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 240, "end_pos": 242 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A685-1", "uniprot_ac": "A0A8V1A685", "uniprot_id": "A0A8V1A685_CHICK", "mass": { "chemical_mass": 27467.0, "monoisotopic_mass": 27467.0 }, "refseq": {}, "gene_names": [ { "name": "YWHAH", "type": "recommended", "evidence": [ { "id": "A0A8V1A685", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A685" } ] } ], "protein_names": [ { "name": "Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta", "type": "synonym", "evidence": [ { "id": "A0A8V1A685", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A685/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A685", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A685" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "YWHAH", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A685", "locus": { "chromosome": "15", "start_pos": 8827695, "end_pos": 8836215, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010026643", "url": "https://www.ensembl.org/id/ENSGALG00010026643" } ] } } ], "crossref": [ { "id": "A0A8V1A685", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A685", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR000308", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000308", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023409", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023409", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023410", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023410", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036815", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036815", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A685", "url": "https://www.orthodb.org/?gene=A0A8V1A685", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR18860", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18860", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00244", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00244", "database": "Pfam", "categories": [ "Protein 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{ "name": "T-helper-inducing POZ/Krueppel-like factor", "type": "synonym", "evidence": [ { "id": "A0A8V1A6C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6C1/entry#names_and_taxonomy" } ] }, { "name": "Zinc finger protein Th-POK", "type": "synonym", "evidence": [ { "id": "A0A8V1A6C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6C1/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A6C1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6C1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ZBTB7B", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6C1", "locus": { "chromosome": "25", "start_pos": 2057737, "end_pos": 2038955, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027940", "url": "https://www.ensembl.org/id/ENSGALG00010027940" } ] } } ], "crossref": [ { "id": "A0A8V1A6C1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A6C1", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd18327", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18327", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "121107583", "url": "https://www.ncbi.nlm.nih.gov/gene/121107583", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050457", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050457", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A6C1", "url": "https://www.orthodb.org/?gene=A0A8V1A6C1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AB78", "url": "https://www.orthodb.org/?gene=A0A8V1AB78", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AE04", "url": "https://www.orthodb.org/?gene=A0A8V1AE04", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AGJ1", "url": "https://www.orthodb.org/?gene=A0A8V1AGJ1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46105", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46105", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46105:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46105:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00651", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00651", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1A6C1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6C1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A6C1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6C1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AB78", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB78", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AB78-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB78-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AE04", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE04", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AE04-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE04-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGJ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGJ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGJ1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQLRVRVQPRTAQRPTSSAPSPPPWDTRGQQLQEWGAPWGAPHTLHPGAVGGRQDPNGGRGSVPALPYGPVLCRCWDAFGAVSHPGSVHPKRCQVRTMASPEDDLIGIPFPEHSSELLSSLNEQRHLGVLCDVTIKTQGLEYRTHRAVLAACSRYFKKLFAGPGPGQEVCELDFVGPEALGALLEFAYTATLTISSSNMGEVLQAAQLLEIPCVIAACADILQCHGLEAPGPDDDDCERARRYLEAFATLPDGDAPAAPPARPAARRSKKTRKFLQARGARLNNHSEEPPAEAEGSHSPLPAPQPPSPPPAPEGLAQPYEPFEVPEEEELPPHAFPFPYQMSPEEGGSDDDAIDPDLMAYLSSLHHEALAPGLDSPDKLVRKRRSQMPQECPVCHKVIHGAGKLPRHMRTHTGEKPFACQVCGVRFTRNDKLKIHMRKHTGERPYSCQHCSARFLHSYDLKNHMHLHTGARPYECYLCHKAFAKDDHLQRHLKGQNCLEVRTRRRRREDPPPPPTPDAPPGIDLSNGRLEGLRLSLARYWGPAQIKEEEEEPEMEMEPEAEEGPQPDGMVPVEMV", "length": 575, "header": "tr|A0A8V1A6C1-1|A0A8V1A6C1_CHICK Isoform 1 of Zinc finger and BTB domain-containing protein 7B OS=Gallus gallus OX=9031 GN=ZBTB7B PE=4 SV=1 CANONICAL=A0A8V1A6C1-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A6C1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6C1/entry#A0A8V1A6C1-1", "sequence": { "sequence": "MQLRVRVQPRTAQRPTSSAPSPPPWDTRGQQLQEWGAPWGAPHTLHPGAVGGRQDPNGGRGSVPALPYGPVLCRCWDAFGAVSHPGSVHPKRCQVRTMASPEDDLIGIPFPEHSSELLSSLNEQRHLGVLCDVTIKTQGLEYRTHRAVLAACSRYFKKLFAGPGPGQEVCELDFVGPEALGALLEFAYTATLTISSSNMGEVLQAAQLLEIPCVIAACADILQCHGLEAPGPDDDDCERARRYLEAFATLPDGDAPAAPPARPAARRSKKTRKFLQARGARLNNHSEEPPAEAEGSHSPLPAPQPPSPPPAPEGLAQPYEPFEVPEEEELPPHAFPFPYQMSPEEGGSDDDAIDPDLMAYLSSLHHEALAPGLDSPDKLVRKRRSQMPQECPVCHKVIHGAGKLPRHMRTHTGEKPFACQVCGVRFTRNDKLKIHMRKHTGERPYSCQHCSARFLHSYDLKNHMHLHTGARPYECYLCHKAFAKDDHLQRHLKGQNCLEVRTRRRRREDPPPPPTPDAPPGIDLSNGRLEGLRLSLARYWGPAQIKEEEEEPEMEMEPEAEEGPQPDGMVPVEMV", "length": 575, "header": "tr|A0A8V1A6C1-1|A0A8V1A6C1_CHICK Isoform 1 of Zinc finger and BTB domain-containing protein 7B OS=Gallus gallus OX=9031 GN=ZBTB7B PE=4 SV=1 CANONICAL=A0A8V1A6C1-1" }, "locus": { "chromosome": "25", "start_pos": 2056733, "end_pos": 2044885, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067723.1", "url": "https://www.ensembl.org/id/ENSGALT00010067723.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041466.1", "url": "https://www.ensembl.org/id/ENSGALP00010041466.1" } ] } }, { "isoform_ac": "A0A8V1AB78-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6C1/entry#A0A8V1AB78-1", "sequence": { "sequence": "MCRFHKVRTMASPEDDLIGIPFPEHSSELLSSLNEQRHLGVLCDVTIKTQGLEYRTHRAVLAACSRYFKKLFAGPGPGQEVCELDFVGPEALGALLEFAYTATLTISSSNMGEVLQAAQLLEIPCVIAACADILQCHGLEAPGPDDDDCERARRYLEAFATLPDGDAPAAPPARPAARRSKKTRKFLQARGARLNNHSEEPPAEAEGSHSPLPAPQPPSPPPAPEGLAQPYEPFEVPEEEELPPHAFPFPYQMSPEEGGSDDDAIDPDLMAYLSSLHHEALAPGLDSPDKLVRKRRSQMPQECPVCHKVIHGAGKLPRHMRTHTGEKPFACQVCGVRFTRNDKLKIHMRKHTGERPYSCQHCSARFLHSYDLKNHMHLHTGARPYECYLCHKAFAKDDHLQRHLKGQNCLEVRTRRRRREDPPPPPTPDAPPGIDLSNGRLEGLRLSLARYWGPAQIKEEEEEPEMEMEPEAEEGPQPDGMVPVEMV", "length": 487, "header": "tr|A0A8V1AB78-1|A0A8V1AB78_CHICK Computationally mapped isoform of Zinc finger and BTB domain-containing protein 7B OS=Gallus gallus OX=9031 GN=ZBTB7B PE=4 SV=1 CANONICAL=A0A8V1A6C1-1" }, "locus": { "chromosome": "25", "start_pos": 2056733, "end_pos": 2044170, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067725.1", "url": "https://www.ensembl.org/id/ENSGALT00010067725.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041468.1", "url": "https://www.ensembl.org/id/ENSGALP00010041468.1" } ] } }, { "isoform_ac": "A0A8V1AE04-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6C1/entry#A0A8V1AE04-1", "sequence": { "sequence": "MASPEDDLIGIPFPEHSSELLSSLNEQRHLGVLCDVTIKTQGLEYRTHRAVLAACSRYFKKLFAGPGPGQEVCELDFVGPEALGALLEFAYTATLTISSSNMGEVLQAAQLLEIPCVIAACADILQCHGLEAPGPDDDDCERARRYLEAFATLPDGDAPAAPPARPAARRSKKTRKFLQARGARLNNHSEEPPAEAEGSHSPLPAPQPPSPPPAPEGLAQPYEPFEVPEEEELPPHAFPFPYQMSPEEGGSDDDAIDPDLMAYLSSLHHEALAPGLDSPDKLVRKRRSQMPQECPVCHKVIHGAGKLPRHMRTHTGEKPFACQVCGVRFTRNDKLKIHMRKHTGERPYSCQHCSARFLHSYDLKNHMHLHTGARPYECYLCHKAFAKDDHLQRHLKGQNCLEVRTRRRRREDPPPPPTPDAPPGIDLSNGRLEGLRLSLARYWGPAQIKEEEEEPEMEMEPEAEEGPQPDGMVPVEMV", "length": 478, "header": "tr|A0A8V1AE04-1|A0A8V1AE04_CHICK Computationally mapped isoform of Zinc finger and BTB domain-containing protein 7B OS=Gallus gallus OX=9031 GN=ZBTB7B PE=4 SV=1 CANONICAL=A0A8V1A6C1-1" }, "locus": { "chromosome": "25", "start_pos": 2056733, "end_pos": 2053432, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067727.1", "url": "https://www.ensembl.org/id/ENSGALT00010067727.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041470.1", "url": "https://www.ensembl.org/id/ENSGALP00010041470.1" } ] } }, { "isoform_ac": "A0A8V1AGJ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6C1/entry#A0A8V1AGJ1-1", "sequence": { "sequence": "MDGRMEMQLRAPRRARVRTMASPEDDLIGIPFPEHSSELLSSLNEQRHLGVLCDVTIKTQGLEYRTHRAVLAACSRYFKKLFAGPGPGQEVCELDFVGPEALGALLEFAYTATLTISSSNMGEVLQAAQLLEIPCVIAACADILQCHGLEAPGPDDDDCERARRYLEAFATLPDGDAPAAPPARPAARRSKKTRKFLQARGARLNNHSEEPPAEAEGSHSPLPAPQPPSPPPAPEGLAQPYEPFEVPEEEELPPHAFPFPYQMSPEEGGSDDDAIDPDLMAYLSSLHHEALAPGLDSPDKLVRKRRSQMPQECPVCHKVIHGAGKLPRHMRTHTGEKPFACQVCGVRFTRNDKLKIHMRKHTGERPYSCQHCSARFLHSYDLKNHMHLHTGARPYECYLCHKAFAKDDHLQRHLKGQNCLEVRTRRRRREDPPPPPTPDAPPGIDLSNGRLEGLRLSLARYWGPAQIKEEEEEPEMEMEPEAEEGPQPDGMVPVEMV", "length": 497, "header": "tr|A0A8V1AGJ1-1|A0A8V1A6C1_CHICK Computationally mapped isoform of Zinc finger and BTB domain-containing protein 7B OS=Gallus gallus OX=9031 GN=ZBTB7B PE=4 SV=1 CANONICAL=A0A8V1A6C1-1" }, "locus": { "chromosome": "25", "start_pos": 2056733, "end_pos": 2040136, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067726.1", "url": "https://www.ensembl.org/id/ENSGALT00010067726.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041469.1", "url": "https://www.ensembl.org/id/ENSGALP00010041469.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 515, "start_aa": "Thr", "end_pos": 515, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr515", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 15, "go_terms": [ { "name": "positive regulation of interleukin-17 production", "id": "GO:0032740", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032740", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A6C1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6C1" } ], "pmid": "" }, { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A6C1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6C1" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A6C1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6C1" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A6C1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6C1" } ], "pmid": "" }, { "name": "positive regulation of gene expression", "id": "GO:0010628", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010628", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A6C1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6C1" } ], "pmid": "" }, { "name": "response to insulin", "id": "GO:0032868", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032868", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A6C1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6C1" } ], "pmid": "" }, { "name": "positive regulation of insulin receptor signaling pathway", "id": "GO:0046628", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046628", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A6C1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6C1" } ], "pmid": "" }, { "name": "positive regulation of CD4-positive, alpha-beta T cell differentiation", "id": "GO:0043372", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043372", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A6C1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6C1" } ], "pmid": "" }, { "name": "NK T cell differentiation", "id": "GO:0001865", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001865", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A6C1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6C1" } ], "pmid": "" }, { "name": "adaptive thermogenesis", "id": "GO:1990845", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990845", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A6C1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6C1" } ], "pmid": "" }, { "name": "positive regulation of cold-induced thermogenesis", "id": "GO:0120162", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120162", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A6C1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6C1" } ], "pmid": "" }, { "name": "negative regulation of CD8-positive, alpha-beta T cell differentiation", "id": "GO:0043377", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043377", 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"sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A6H3-1", "uniprot_ac": "A0A8V1A6H3", "uniprot_id": "A0A8V1A6H3_CHICK", "mass": { "chemical_mass": 40269.0, "monoisotopic_mass": 40269.0 }, "refseq": {}, "gene_names": [ { "name": "RABEPK", "type": "recommended", "evidence": [ { "id": "A0A8V1A6H3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6H3" } ] } ], "protein_names": [ { "name": "Rab9 effector protein with kelch motifs", "type": "recommended", "evidence": [ { "id": "A0A8V1A6H3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6H3/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Rab9 effector required for endosome to trans-Golgi network (TGN) transport.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGN7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGN7#function" }, { "database": "UniProtKB", "id": "ARBA00037224", "url": "https://www.uniprot.org/uniprotkb/ARBA00037224#function" }, { "database": "UniProtKB", "id": "A0A8V1A6H3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6H3#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A6H3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6H3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RABEPK", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6H3", "locus": { "chromosome": "17", "start_pos": 10202220, "end_pos": 10196538, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027964", "url": "https://www.ensembl.org/id/ENSGALG00010027964" } ] } } ], "crossref": [ { "id": "A0A8V1A6H3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A6H3", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR006652", "url": 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"categories": [ "Protein Classification" ] }, { "id": "PF24681", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24681", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-6811440", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6811440", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1A6H3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6H3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A6H3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6H3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGN7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGN7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGN7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGN7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGPRVLPLLEPGCRPQAGKWYRMAPRGEWPRGRVGHGCLFVPGGSGRVLLLGGADPAGAFADAHFVELGAHLWAPAAWSGLRPRYEHATFLSACRPPRLWVFGGAHRAGNRSCVQVLDPEIGTWESPEVTGIPPLPRTFHTSSAAIGDCLYVFGGGDKGAEPVKDQQLHVFDTVALAWTQPDTRGDPPSPRHGHVVVAVGTKLFIHGGLAGDIFYNDLFCIDTTDMKWVKIAATGDVPGGRASHSSAVFKDHLYIFGGIGPDGTLDTTYKYHIEEQQWTLLQFDSPLPAGRLDHAMCVIPWRVGKNGDAAAVSKEDKAEPTASAGDRADHLCRGQDKKACTEDTMMHLLLIFGGMDTQAEIYRDCICLCLQL", "length": 372, "header": "tr|A0A8V1A6H3-1|A0A8V1A6H3_CHICK Isoform 1 of Rab9 effector protein with kelch motifs OS=Gallus gallus OX=9031 GN=RABEPK PE=4 SV=1 CANONICAL=A0A8V1A6H3-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A6H3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6H3/entry#A0A8V1A6H3-1", "sequence": { "sequence": "MGPRVLPLLEPGCRPQAGKWYRMAPRGEWPRGRVGHGCLFVPGGSGRVLLLGGADPAGAFADAHFVELGAHLWAPAAWSGLRPRYEHATFLSACRPPRLWVFGGAHRAGNRSCVQVLDPEIGTWESPEVTGIPPLPRTFHTSSAAIGDCLYVFGGGDKGAEPVKDQQLHVFDTVALAWTQPDTRGDPPSPRHGHVVVAVGTKLFIHGGLAGDIFYNDLFCIDTTDMKWVKIAATGDVPGGRASHSSAVFKDHLYIFGGIGPDGTLDTTYKYHIEEQQWTLLQFDSPLPAGRLDHAMCVIPWRVGKNGDAAAVSKEDKAEPTASAGDRADHLCRGQDKKACTEDTMMHLLLIFGGMDTQAEIYRDCICLCLQL", "length": 372, "header": "tr|A0A8V1A6H3-1|A0A8V1A6H3_CHICK Isoform 1 of Rab9 effector protein with kelch motifs OS=Gallus gallus OX=9031 GN=RABEPK PE=4 SV=1 CANONICAL=A0A8V1A6H3-1" }, "locus": { "chromosome": "17", "start_pos": 10200516, "end_pos": 10196615, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067778.1", "url": "https://www.ensembl.org/id/ENSGALT00010067778.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041521.1", "url": "https://www.ensembl.org/id/ENSGALP00010041521.1" } ] } }, { "isoform_ac": "A0A8V1AGN7-1", "url": 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A6H4-1", "uniprot_ac": "A0A8V1A6H4", "uniprot_id": "A0A8V1A6H4_CHICK", "mass": { "chemical_mass": 14722.0, "monoisotopic_mass": 14722.0 }, "refseq": { "ac": "XP_040548155", "name": "feather keratin Cos1-1/Cos1-3/Cos2-1-like isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040548155" }, "gene_names": [ { "name": "LOC124417024", "type": "recommended", "evidence": [ { "id": "A0A8V1A6H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6H4" } ] }, { "name": "LOC124417024", "type": "synonym", "evidence": [ { "id": "XP_040548155", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040548155" } ] } ], "protein_names": [ { "name": "Keratin", "type": "recommended", "evidence": [ { "id": "A0A8V1A6H4", "database": "UniProtKB", "url": 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This record is derived from a genomic sequence (NC_052599.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040548155", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040548155" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A6H4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6H4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC124417024", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6H4", "locus": {} } ], "crossref": [ { "id": "A0A8V1A6H4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A6H4", "database": "AlphaFoldDB", "categories": [] }, { "id": "124417024", "url": "https://www.ncbi.nlm.nih.gov/gene/124417024", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003461", "url": 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"MPLDIGHLRSIIKGTPAPGSLIHCFYLLLLGNQVHLQSQDMSCCDQCVPCQPCGPTPLASSCNEPCVRQCQNSTIVIEPSPVVVTLPGPILSSFPQNTAVGSSTSAAVGSILSCQGVPITSGGFDLSCISNRYCGRRCTPC", "length": 141, "header": "tr|A0A8V1A6H4-1|A0A8V1A6H4_CHICK Isoform 1 of Keratin OS=Gallus gallus OX=9031 GN=LOC124417024 PE=3 SV=1 CANONICAL=A0A8V1A6H4-1" }, "locus": { "chromosome": "27", "start_pos": 481206, "end_pos": 480401, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065075.1", "url": "https://www.ensembl.org/id/ENSGALT00010065075.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039691.1", "url": "https://www.ensembl.org/id/ENSGALP00010039691.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 56, 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"https://www.ebi.ac.uk/QuickGO/term/GO:0005882", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A6H4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6H4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 72, "end_pos": 74, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 56 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 72, "end_pos": 74 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { 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} ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A6K1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6K1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LRSAM1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6K1", "locus": { "chromosome": "17", "start_pos": 2204935, "end_pos": 2230389, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027976", "url": "https://www.ensembl.org/id/ENSGALG00010027976" } ] } } ], "crossref": [ { "id": "A0A8V1A6K1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A6K1", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd09523", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09523", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd16515", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16515", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "417265", "url": "https://www.ncbi.nlm.nih.gov/gene/417265", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001660", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001660", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003591", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003591", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013761", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013761", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050216", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050216", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055414", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055414", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:417265", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417265", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LWCSSEC", "url": "https://omabrowser.org/oma/group/LWCSSEC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A6K1", "url": "https://www.orthodb.org/?gene=A0A8V1A6K1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ABF0", "url": "https://www.orthodb.org/?gene=A0A8V1ABF0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ABF4", "url": "https://www.orthodb.org/?gene=A0A8V1ABF4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AE80", "url": "https://www.orthodb.org/?gene=A0A8V1AE80", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AE84", "url": "https://www.orthodb.org/?gene=A0A8V1AE84", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AGR7", "url": "https://www.orthodb.org/?gene=A0A8V1AGR7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AIK9", "url": "https://www.orthodb.org/?gene=A0A8V1AIK9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48051", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48051", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR48051:SF47", "url": 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"MPLFFRKKKPSEDARKRLEYQMCLAKEAGADDVLDISKCELLEVPYGAFATCKVLQKKVLIIHTNNLTSLVPKSCSLLSLITVKVLDLHDNQLASLPADIGQLTSLQCISDGSFCFGVQLWIHITVQSPGSCVSWGRVAGEVLNLERNLLKCLPQSIGDLAQLQVLNVKGNKLRELPATVSGLRSLRTLNVSENLLQELPRVLAHVRTLETLTLDASSMTYPSPDICSAGTESIQQFLCKECGIAYYPPSEYVLPALESDGGETSVDGVDRTVHKYLEEESKWQNKFSDYEKRKEKKMQEKLEFERRLNMGQREHALLVQQINNQKGEILQTVREDQMRLEEGLTKHQRHLEEERLKLLQQLKQAEQGIASRIQKLIEDNQRQKQSSDILKSLENERLRMEQLMAITQEETEHLRRREVASAMQQMLAESYKNKLIQMTYESRRQDLVSQACSSLAEMDQKFQQILAWQQMDQNKAVSQILQQSEMQKAAFEALQVKKDLMHRQIRNQIKLIETELLQLTQLELKRQELDTETLQGMIMEQRQALGYLLQQLLKEKKQREEELQQILLEMEAKSETKQENYWLIQYQRLLNQKPLSLKLQEEGLEKQLVNLLIELSAEQYVPVFAHHRISLEMLSTMTASDLEKMGIAETGLQHAILRRAQEILAVAKMIPELLRTEDAEIPAAAQPSAPEEEAPSSVVPTAPLLQWDEKKSECVVCMEQEAQMIFLPCGHVCCCQTCCKRLQTCPLCRRDITQHVRIFYSS", "length": 762, "header": "tr|A0A8V1A6K1-1|A0A8V1A6K1_CHICK Isoform 1 of Leucine rich repeat and sterile alpha motif containing 1 OS=Gallus gallus OX=9031 GN=LRSAM1 PE=1 SV=1 CANONICAL=A0A8V1A6K1-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A6K1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6K1/entry#A0A8V1A6K1-1", "sequence": { "sequence": "MPLFFRKKKPSEDARKRLEYQMCLAKEAGADDVLDISKCELLEVPYGAFATCKVLQKKVLIIHTNNLTSLVPKSCSLLSLITVKVLDLHDNQLASLPADIGQLTSLQCISDGSFCFGVQLWIHITVQSPGSCVSWGRVAGEVLNLERNLLKCLPQSIGDLAQLQVLNVKGNKLRELPATVSGLRSLRTLNVSENLLQELPRVLAHVRTLETLTLDASSMTYPSPDICSAGTESIQQFLCKECGIAYYPPSEYVLPALESDGGETSVDGVDRTVHKYLEEESKWQNKFSDYEKRKEKKMQEKLEFERRLNMGQREHALLVQQINNQKGEILQTVREDQMRLEEGLTKHQRHLEEERLKLLQQLKQAEQGIASRIQKLIEDNQRQKQSSDILKSLENERLRMEQLMAITQEETEHLRRREVASAMQQMLAESYKNKLIQMTYESRRQDLVSQACSSLAEMDQKFQQILAWQQMDQNKAVSQILQQSEMQKAAFEALQVKKDLMHRQIRNQIKLIETELLQLTQLELKRQELDTETLQGMIMEQRQALGYLLQQLLKEKKQREEELQQILLEMEAKSETKQENYWLIQYQRLLNQKPLSLKLQEEGLEKQLVNLLIELSAEQYVPVFAHHRISLEMLSTMTASDLEKMGIAETGLQHAILRRAQEILAVAKMIPELLRTEDAEIPAAAQPSAPEEEAPSSVVPTAPLLQWDEKKSECVVCMEQEAQMIFLPCGHVCCCQTCCKRLQTCPLCRRDITQHVRIFYSS", "length": 762, "header": "tr|A0A8V1A6K1-1|A0A8V1A6K1_CHICK Isoform 1 of Leucine rich repeat and sterile alpha motif containing 1 OS=Gallus gallus OX=9031 GN=LRSAM1 PE=1 SV=1 CANONICAL=A0A8V1A6K1-1" }, "locus": { "chromosome": "17", "start_pos": 2228251, "end_pos": 2205840, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067809.1", "url": "https://www.ensembl.org/id/ENSGALT00010067809.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041552.1", "url": "https://www.ensembl.org/id/ENSGALP00010041552.1" } ] } }, { "isoform_ac": "A0A8V1ABF0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6K1/entry#A0A8V1ABF0-1", "sequence": { "sequence": "MPLFFRKKKPSEDARKRLEYQMCLAKEAGADDVLDISKCELLEVPYGAFATCKVLQKKVLIIHTNNLTSLVPKSCSLLSLITVKVLDLHDNQLASLPADIGQLTSLQVLNLERNLLKCLPQSIGDLAQLQVLNVKGNKLRELPATVSGLRSLRTLNVSENLLQELPRVLAHVRTLETLTLDASSMTYPSPDICSAGTESIQQFLCKECGIAYYPPSEYVLPALESDGGETSVDGVDRTVHKYLEEESKWQEKKMQEKLEFERRLNMGQREHALLVQQINNQKGEILQTVREDQMRLEEGLTKHQRHLEEERLKLLQQLKQAEQGIASRIQKLIEDNQRQKQSSDILKSLENERLRMEQLMAITQEETEHLRRREVASAMQQMLAESYKNKLIQMTYESRRQDLVSQACSSLAEMDQKFQQILAWQQMDQNKAVSQILQQSEMQKAAFEALQVKKDLMHRQIRNQIKLIETELLQLTQLELKRQELDTETLQGMIMEQRQALGYLLQQLLKEKKQREEELQQILLEMEAKSETKQENYWLIQYQRLLNQKPLSLKLQEEGLEKQLVNLLIELSAEQYVPVFAHHRISLEMLSTMTASDLEKMGIAETGLQHAILRRAQEILAVAKMIPELLRTEDAEIPAAAQPSAPEEEAPSSVVPTAPLLQWDEKKSECVVCMEQEAQMIFLPCGHVCCCQTCCKRLQTCPLCRRDITQHVRIFYSS", "length": 718, "header": "tr|A0A8V1ABF0-1|A0A8V1ABF0_CHICK Computationally mapped isoform of Leucine rich repeat and sterile alpha motif containing 1 OS=Gallus gallus OX=9031 GN=LRSAM1 PE=1 SV=1 CANONICAL=A0A8V1A6K1-1" }, "locus": { "chromosome": "17", "start_pos": 2228251, "end_pos": 2205840, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067806.1", "url": "https://www.ensembl.org/id/ENSGALT00010067806.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041549.1", "url": "https://www.ensembl.org/id/ENSGALP00010041549.1" } ] } }, { "isoform_ac": "A0A8V1ABF4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6K1/entry#A0A8V1ABF4-1", "sequence": { "sequence": "MMQLCETLGRFAPGPEADGTLCVPYGAFATCKVLQKKVLIIHTNNLTSLVPKSCSLLSLITVKVLDLHDNQLASLPADIGQLTSLQVLNLERNLLKCLPQSIGDLAQLQVLNVKGNKLRELPATVSGLRSLRTLNVSENLLQELPRVLAHVRTLETLTLDASSMTYPSPDICSAGTESIQQFLCKECGIAYYPPSEYVLPALESDGGETSVDGVDRTVHKYLEEESKWQNKFSDYEKRKEKKMQEKLEFERRLNMGQREHALLVQQINNQKGEILQTVREDQMRLEEGLTKHQRHLEEERLKLLQQLKQAEQGIASRIQKLIEDNQRQKQSSDILKSLENERLRMEQLMAITQEETEHLRRREVASAMQQMLAESYKNKLIQMTYESRRQDLVSQACSSLAEMDQKFQQILAWQQMDQNKAVSQILQQSEMQKAAFEALQVKKDLMHRQIRNQIKLIETELLQLTQLELKRQELDTETLQGMIMEQRQALGYLLQQLLKEKKQREEELQQILLEMEAKSETKQENYWLIQYQRLLNQKPLSLKLQEEGLEKQLVNLLIELSAEQYVPVFAHHRISLEMLSTMTASDLEKMGIAETGLQHAILRRAQEILAVAKMIPELLRTEDAEIPAAAQPSAPEEEAPSSVVPTAPLLQWDEKKSECVVCMEQEAQMIFLPCGHVCCCQTCCKRLQTCPLCRRDITQHVRIFYSS", "length": 707, "header": "tr|A0A8V1ABF4-1|A0A8V1ABF4_CHICK Computationally mapped isoform of Leucine rich repeat and sterile alpha motif containing 1 OS=Gallus gallus OX=9031 GN=LRSAM1 PE=1 SV=1 CANONICAL=A0A8V1A6K1-1" }, "locus": { "chromosome": "17", "start_pos": 2225636, "end_pos": 2205840, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067811.1", "url": "https://www.ensembl.org/id/ENSGALT00010067811.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041554.1", "url": "https://www.ensembl.org/id/ENSGALP00010041554.1" } ] } }, { "isoform_ac": "A0A8V1AE80-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6K1/entry#A0A8V1AE80-1", "sequence": { "sequence": "MLILLLLDISKVVWKAKEAGADDVLDISKCELLEVPYGAFATCKVLQKKVLIIHTNNLTSLVPKSCSLLSLITVKVLDLHDNQLASLPADIGQLTSLQVLNLERNLLKCLPQSIGDLAQLQVLNVKGNKLRELPATVSGLRSLRTLNVSENLLQELPRVLAHVRTLETLTLDASSMTYPSPDICSAGTESIQQFLCKECGIAYYPPSEYVLPALESDGGETSVDGVDRTVHKYLEEESKWQNKFSDYEKRKEKKMQEKLEFERRLNMGQREHALLVQQINNQKGEILQTVREDQMRLEEGLTKHQRHLEEERLKLLQQLKQAEQGIASRIQKLIEDNQRQKQSSDILKSLENERLRMEQLMAITQEETEHLRRREVASAMQQMLAESYKNKLIQMTYESRRQDLVSQACSSLAEMDQKFQQILAWQQMDQNKAVSQILQQSEMQKAAFEALQVKKDLMHRQIRNQIKLIETELLQLTQLELKRQELDTETLQGMIMEQRQALGYLLQQLLKEKKQREEELQQILLEMEAKSETKQENYWLIQYQRLLNQKPLSLKLQEEGLEKQLVNLLIELSAEQYVPVFAHHRISLEMLSTMTASDLEKMGIAETGLQHAILRRAQEILAVAKMIPELLRTEDAEIPAAAQPSAPEEEAPSSVVPTAPLLQWDEKKSECVVCMEQEAQMIFLPCGHVCCCQTCCKRLQTCPLCRRDITQHVRIFYSS", "length": 719, "header": "tr|A0A8V1AE80-1|A0A8V1AE80_CHICK Computationally mapped isoform of Leucine rich repeat and sterile alpha motif containing 1 OS=Gallus gallus OX=9031 GN=LRSAM1 PE=1 SV=1 CANONICAL=A0A8V1A6K1-1" }, "locus": { "chromosome": "17", "start_pos": 2227308, "end_pos": 2205840, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067803.1", "url": "https://www.ensembl.org/id/ENSGALT00010067803.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041546.1", "url": "https://www.ensembl.org/id/ENSGALP00010041546.1" } ] } }, { "isoform_ac": "A0A8V1AE84-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6K1/entry#A0A8V1AE84-1", "sequence": { "sequence": "MPLFFRKKKPSEDARKRLEYQMCLAKEAGADDVLDISKCELLEVPYGAFATCKVLQKKVLIIHTNNLTSLVPKSCSLLSLITVKVLDLHDNQLASLPADIGQLTSLQVLNLERNLLKCLPQSIGDLAQLQVLNVKGNKLRELPATVSGLRSLRTLNVSENLLQELPRVLAHVRTLETLTLDASSMTYPSPDICSAGTESIQQFLCKECGIAYYPPSEYVLPALESDGGETSVDGVDRTVHKYLEEESKWQNKFSDYEKRKEKKMQEKLEFERRLNMGQREHALLVQQINNQKGEILQTVREDQMRLEEGLTKHQRHLEEERLKLLQQLKQAEQGIASRIQKLIEDNQRQKQSSDILKSLENERLRMEQLMAITQEETEHLRRREVASAMQQMLAESYKNKLIQMTYESRRQDLVSQACSSLAEMDQKFQQILAWQQMDQNKAVSQILQQSEMQKAAFEALQVKKDLMHRQIRNQIKLIETELLQLTQLELKRQELDTETLQGMIMEQRQALGYLLQQLLKEKKQREEELQQILEEGLEKQLVNLLIELSAEQYVPVFAHHRISLEMLSTMTASDLEKMGIAETGLQHAILRRAQEILAVAKMIPELLRTEDAEIPAAAQPSAPEEEAPSSVVPTAPLLQWDEKKSECVVCMEQEAQMIFLPCGHVCCCQTCCKRLQTCPLCRRDITQHVRIFYSS", "length": 695, "header": "tr|A0A8V1AE84-1|A0A8V1AE84_CHICK Computationally mapped isoform of Leucine rich repeat and sterile alpha motif containing 1 OS=Gallus gallus OX=9031 GN=LRSAM1 PE=1 SV=1 CANONICAL=A0A8V1A6K1-1" }, "locus": { "chromosome": "17", "start_pos": 2228251, "end_pos": 2205840, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067808.1", "url": "https://www.ensembl.org/id/ENSGALT00010067808.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041551.1", "url": "https://www.ensembl.org/id/ENSGALP00010041551.1" } ] } }, { "isoform_ac": "A0A8V1AGR7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6K1/entry#A0A8V1AGR7-1", "sequence": { "sequence": "MPLFFRKKKPSEDARKRLEYQMCLAKEAGADDVLDISKCELLEVPYGAFATCKVLQKKVLIIHTNNLTSLVPKSCSLLSLITVKVLDLHDNQLASLPADIGQLTSLQVLNLERNLLKCLPQSIGDLAQLQVLNVKGNKLRELPATVSGLRSLRTLNVSENLLQELPRVLAHVRTLETLTLDASSMTYPSPDICSAGTESIQQFLCKECGIAYYPPSEYVLPALESDGGETSVDGVDRTVHKYLEEESKWQNKFSDYEKRKEKKMQEKLEFERRLNMGQREHALLVQQINNQKGEILQTVREDQMRLEEGLTKHQRHLEEERLKLLQQLKQAEQGIASRIQKLIEDNQRQKQSSDILKSLENERLRMEQLMAITQEETEHLRRREVASAMQQMLAESYKNKLIQMTYESRRQDLVSQACSSLAEMDQKFQQILAWQQMDQNKAVSQILQQSEMQKAAFEALQVKKDLMHRQIRNQIKLIETELLQLTQLELKRQELDTETLQGMIMEQRQALGYLLQQLLKEKKQREEELQQILLEMEAKSETKQENYWLIQYQRLLNQKPLSLKLQEEGLEKQLVNLLIELSAEQYVPVFAHHRISLEMLSTMTASDLEKMGIAETGLQHAILRRAQEILAVAKMIPELLRTEDAEIPAAAQPSAPEEEAPSSVVPTAPLLQWDEKKSECVVCMEQEAQMIFLPCGHVCCCQTCCKRLQTCPLCRRDITQHVRIFYSS", "length": 728, "header": "tr|A0A8V1AGR7-1|A0A8V1A6K1_CHICK Computationally mapped isoform of Leucine rich repeat and sterile alpha motif containing 1 OS=Gallus gallus OX=9031 GN=LRSAM1 PE=1 SV=1 CANONICAL=A0A8V1A6K1-1" }, "locus": { "chromosome": "17", "start_pos": 2228251, "end_pos": 2205840, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067807.1", "url": "https://www.ensembl.org/id/ENSGALT00010067807.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041550.1", "url": "https://www.ensembl.org/id/ENSGALP00010041550.1" } ] } }, { "isoform_ac": "A0A8V1AIK9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6K1/entry#A0A8V1AIK9-1", "sequence": { "sequence": "MPLFFRKKKPSEDARKRLEYQMCLAKEAGADDVLDISKCELLEVPYGAFATCKVLQKKVLIIHTNNLTSLVPKSCSLLSLITVKVLDLHDNQLASLPADIGQLTSLQVLNLERNLLKCLPQSIGDLAQLQVLNVKGNKLRELPATVSGLRSLRTLNVSENLLQELPRVLAHVRTLETLTLDASSMTYPSPDICSAGTESIQQFLCKECGIAYYPPSEYVLPALESDGGETSVDGVDRTVHKYLEEESKWQNKFSDYEKRKEKKMQEKLEFERRLNMGQREHALLVQQINNQKGEILQTVREDQMRLEEGLTKHQRHLEEERLKLLQQLKQAEQGIASRIQKLIEDNQRQKQSSDILKSLENERLRMEQLMAITQEETEHLRRREVASAMQQMLAESYKNKLIQMTYESRRQDLVSQACSSLAEMDQKFQQILAWQQMDQNKAVSQILQQSEMQKAAFEALQVKKDLMHRQIRNQGMIMEQRQALGYLLQQLLKEKKQREEELQQILLEMEAKSETKQENYWLIQYQRLLNQKPLSLKLQEEGLEKQLVNLLIELSAEQYVPVFAHHRISLEMLSTMTASDLEKMGIAETGLQHAILRRAQEILAVAKMIPELLRTEDAEIPAAAQPSAPEEEAPSSVVPTAPLLQWDEKKSECVVCMEQEAQMIFLPCGHVCCCQTCCKRLQTCPLCRRDITQHVRIFYSS", "length": 701, "header": "tr|A0A8V1AIK9-1|A0A8V1A6K1_CHICK Computationally mapped isoform of Leucine rich repeat and sterile alpha motif containing 1 OS=Gallus gallus OX=9031 GN=LRSAM1 PE=1 SV=1 CANONICAL=A0A8V1A6K1-1" }, "locus": { "chromosome": "17", "start_pos": 2228251, "end_pos": 2205840, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067805.1", "url": "https://www.ensembl.org/id/ENSGALT00010067805.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041548.1", "url": "https://www.ensembl.org/id/ENSGALP00010041548.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 701, "start_aa": "Thr", "end_pos": 701, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr701", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:417265", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417265", "resource": "KEGG Pathway" }, { "id": "R-GGA-983168", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983168", "resource": "Reactome", "description": "Antigen processing: Ubiquitination & Proteasome degradation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6AEY5-1", "protein_name": "E3 ubiquitin-protein ligase LRSAM1", "gene_name": "Lrsam1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPLFFRKRKPSEEARKRLEYQMCLAKEAGADDILDISKCELSEIPFGAFATCKVLQKKVLIVHTNHLTSLLPKSCSLLSLATIKVLDLHDNQLTALPDDIGQLTALQVLNVERNQLTHLPRSVGNLLQLQTLNVKDNKLKELPDTLGELRSLRTLDISENEIQRLPQMLAHVRTLETLSLDALSMVYPPPEVCGAGTAAVQQFLCKESGLDYYPPSQYLLPVLEQDGAENSQDSPDGPTRRFSREEAEWQNRFSDYEKRKEQKMLEKLEFERRLDLGQREHAELLQQSHSHKDEILQTVKQEQTRLEQGLSERQRCLDAERQQLQEQLKQSEQSIASRIQRLLQDNQRQKKSSEILKSLENERIRMEQLMSITQEETENLRQREIAAAMQQMLTESCKSRLIQMAYESQRQSLVQQACSSMAEMDKRFQQILSWQQMDQNKAISQILQESVMQKAAFEALQVKKDLTHRQIRSQIRLIETELLQLTQLELKRKSLDTETLQEMVSEQRWALSNLLQQLLKEKKQREEELHGILAELEAKSETKQENYWLIQYQRLLNQKPLSLKLQEEGMERQLVALLVELSAEHYLPLFAHHRITLDMLSRMGPGDLAKVGVSEAGLQHEILRRARDLLDVARVQPELKPPKNEVFGVSEPPTAPQELPESVRPSAPPAELDVPTSECVVCLEREAQMVFLTCGHVCCCQQCCQPLRTCPLCRQEISQRLRIYHSS", "length": 727 }, "evidence": [ { "id": "A0A8V1A6K1", "url": "https://omabrowser.org/oma/group/A0A8V1A6K1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1RS16-1", "protein_name": "Leucine rich repeat and sterile alpha motif containing 1", "gene_name": "LRSAM1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPLFFRKRKPSEEARKRLEYQMCLAKEAGADDILDISNCELSEIPSGAFATCKVLQKKVLIVHTNHLTSLLPKSCSLLSLATIKVLDLHDNQLTALPDDIGQLTALQVLNVERNQLTSLPRSIGNLIQLQTLNLKDNKLKELPDTLGELRSLRTLDISDNKVQRLPQMLAHVRTLETLSLDASSMVYPPQEVCSAGTEAIQQFLCKALGLEYYPPSQYLLPVLEQDGTKTSQDSPDGPSDRFCREEVEWQNRFSDYEKRKEQKMLEKLEFERRLELGQREHAQLLQQSNSQKDEILQTVKEEQSRLEQGLSERQCYLDAERQRLQEQLKQTEQSISSRIQKLLQENQRQKKNSEILKSLENERIRMEQLVSITQEETENLRRREVASAMQQMLSEVYQSRLIQIACEAHGQNLVQQTCSSMAEMGERFQQILSRQQMDKKKVISQILQESAMQKAAFEALQVKKDLMHRQIWKQIKLIETELLQLTQLELKRKSLDTEALQEMISEQRWALSSLLQQLLKEKTQREEELREILMELEAKSESKQENYWLIQYQRLLNQKPLSLKLQEEGLERQLVALLVELSAEHYLPIFAHHRISLDMLSRMGPRDLAKVGVSEAGLQHQILRRAQELLDAARTQPELLTPPKDEVLPTAPEEPPESVEPSAPPEELEAQISECVVCLELEVSLGQQAHPEPLGQAQVIFLNCGHVCCCRQCSQRLRTCPLCRQDIVQGLCIYSSR", "length": 737 }, "evidence": [ { "id": "A0A8V1A6K1", "url": "https://omabrowser.org/oma/group/A0A8V1A6K1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q6UWE0-1", "protein_name": "E3 ubiquitin-protein ligase LRSAM1", "gene_name": "LRSAM1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPLFFRKRKPSEEARKRLEYQMCLAKEAGADDILDISKCELSEIPFGAFATCKVLQKKVLIVHTNHLTSLLPKSCSLLSLATIKVLDLHDNQLTALPDDLGQLTALQVLNVERNQLMQLPRSIGNLTQLQTLNVKDNKLKELPDTVGELRSLRTLNISGNEIQRLPQMLAHVRTLEMLSLDASAMVYPPREVCGAGTAAILQFLCKESGLEYYPPSQYLLPILEQDGIENSRDSPDGPTDRFSREELEWQNRFSDYEKRKEQKMLEKLEFERRLELGQREHTQLLQQSSSQKDEILQTVKEEQSRLEQGLSEHQRHLNAERQRLQEQLKQTEQNISSRIQKLLQDNQRQKKSSEILKSLENERIRMEQLMSITQEETESLRRRDVASAMQQMLTESCKNRLIQMAYESQRQNLVQQACSSMAEMDERFQQILSWQQMDQNKAISQILQESAMQKAAFEALQVKKDLMHRQIRSQIKLIETELLQLTQLELKRKSLDTESLQEMISEQRWALSSLLQQLLKEKQQREEELREILTELEAKSETRQENYWLIQYQRLLNQKPLSLKLQEEGMERQLVALLEELSAEHYLPIFAHHRLSLDLLSQMSPGDLAKVGVSEAGLQHEILRRVQELLDAARIQPELKPPMGEVVTPTAPQEPPESVRPSAPPAELEVQASECVVCLEREAQMIFLNCGHVCCCQQCCQPLRTCPLCRQDIAQRLRIYHSS", "length": 723 }, "evidence": [ { "id": "A0A8V1A6K1", "url": "https://omabrowser.org/oma/group/A0A8V1A6K1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q80ZI6-1", "protein_name": "E3 ubiquitin-protein ligase LRSAM1", "gene_name": "Lrsam1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPLFFRKRKPSEEARKRLEYQMCLAKEAGADDILDISKCELSEIPFGAFATCKVLQKKVLIVHTNHLTSLLPKSCSLLSLVTIKVLDLHENQLTALPDDMGQLTVLQVLNVERNQLTHLPRSIGNLLQLQTLNVKDNKLKELPDTLGELRSLRTLDISENEIQRLPQMLAHVRTLETLSLNALAMVYPPPEVCGAGTAAVQQFLCKESGLDYYPPSQYLLPVLEQDGAENTQDSPDGPASRFSREEAEWQNRFSDYEKRKEQKMLEKLEFERRLDLGQREHAELLQQSHSHKDEILQTVKQEQTRLEQDLSERQRCLDAERQQLQEQLKQTEQSIASRIQRLLQDNQRQKKSSEILKSLENERIRMEQLMSITQEETENLRQREIAAAMQQMLTESCKSRLIQMAYESQRQSLAQQACSSMAEMDKRFQQILSWQQMDQNKAISQILQESVMQKAAFEALQVKKDLMHRQIRNQIRLIETELLQLTQLELKRKSLDTETLQEMVSEQRWALSNLLQQLLKEKKQREEELHGILAELEAKSETKQENYWLIQYQRLLNQKPLSLKLQEEGMERRLVALLVELSAEHYLPLFAHHRISLDMLSRMSPGDLAKVGVSEAGLQHEILRRAQDLLAVPRVQPELKPLENEVLGALEPPTAPRELQESVRPSAPPAELDMPTSECVVCLEREAQMVFLTCGHVCCCQQCCQPLRTCPLCRQEISQRLRIYHSS", "length": 727 }, "evidence": [ { "id": "A0A8V1A6K1", "url": "https://omabrowser.org/oma/group/A0A8V1A6K1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 8, "go_terms": [ { "name": "negative regulation of endocytosis", "id": "GO:0045806", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045806", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A6K1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6K1" } ], "pmid": "" }, { "name": "protein polyubiquitination", "id": "GO:0000209", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000209", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A6K1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6K1" } ], "pmid": "" }, { "name": "protein autoubiquitination", "id": "GO:0051865", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051865", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A6K1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6K1" } ], "pmid": "" }, { "name": "protein catabolic process", "id": "GO:0030163", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030163", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A6K1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6K1" } ], "pmid": "" }, { "name": "positive regulation of autophagosome assembly", "id": "GO:2000786", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000786", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A6K1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6K1" } ], "pmid": "" }, { "name": "viral budding", "id": "GO:0046755", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046755", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A6K1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6K1" } ], "pmid": "" }, { "name": "ubiquitin-dependent endocytosis", "id": "GO:0070086", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070086", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A6K1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6K1" } ], "pmid": "" }, { "name": "positive regulation of xenophagy", "id": "GO:1904417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904417", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A6K1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6K1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A6K1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6K1" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A6K1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6K1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A6K1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6K1" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A6K1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6K1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 190, "end_pos": 192, "annotation": "n_glycosylation_sequon" }, { "start_pos": 66, "end_pos": 68, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1A6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6K1" }, { "id": "PS50089", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50089" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RING-type", "eco_id": "ECO_0000259", "start_pos": 714, "end_pos": 749, "start_aa": "Cys", "end_aa": "Arg", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1A6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6K1" }, { "id": "PS50105", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50105" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SAM", "eco_id": "ECO_0000259", "start_pos": 606, "end_pos": 666, "start_aa": "Lys", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 701 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 190, "end_pos": 192 }, { "start_pos": 66, "end_pos": 68 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { 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"exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A6K3-1", "uniprot_ac": "A0A8V1A6K3", "uniprot_id": "A0A8V1A6K3_CHICK", "mass": { "chemical_mass": 59861.0, "monoisotopic_mass": 59861.0 }, "refseq": { "ac": "XP_421944", "name": "protein FAM117B isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_421944" }, "gene_names": [ { "name": "FAM117B", "type": "recommended", "evidence": [ { "id": "A0A8V1A6K3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6K3" } ] }, { "name": "FAM117B", "type": "synonym", "evidence": [ { "id": "XP_421944", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_421944" } ] } ], "protein_names": [ { "name": "Family with sequence similarity 117 member B", "type": "synonym", "evidence": [ { "id": "A0A8V1A6K3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6K3/entry#names_and_taxonomy" } ] }, { "name": "protein FAM117B isoform X1", "type": "synonym", "evidence": [ { "id": "XP_421944", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_421944" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052538.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_421944.5. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_421944", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_421944" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A6K3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6K3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FAM117B", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6K3", "locus": { "chromosome": "7", "start_pos": 11571250, "end_pos": 11547820, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010025222", "url": "https://www.ensembl.org/id/ENSGALG00010025222" } ] } } ], "crossref": [ { "id": "A0A8V1A6K3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A6K3", "database": "AlphaFoldDB", "categories": [] }, { "id": "424088", "url": "https://www.ncbi.nlm.nih.gov/gene/424088", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026642", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026642", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PREIPQF", "url": "https://omabrowser.org/oma/group/PREIPQF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A6K3", "url": "https://www.orthodb.org/?gene=A0A8V1A6K3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14972", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14972", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14972:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14972:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15388", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15388", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_421944", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_421944", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1A6K3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6K3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A6K3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6K3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSHQRVRRGGSPTPAASPGGGGAAAAGGGAGASGRLQPMRATVPFQLKQQQQHGSPTRSGASAPGGGLARAAAASRSISPTRATPTGGRAGPATAAQTPGGGGSPTRGGGGARGSPPRPHQLPPPPPPPPPPVACGPSPCSSPLPEGSSTAGRVRHPRHSPEQGRSSPERKSPGSPGCKADKSRPPSSSPSSIIRRTSSLDTLAAPYLAGQWPRDNHGQAVPCMRDKATQTESAWAEEYLEKKRSSHKRSASWGSTEQLKEIAKLRQQLQRSKHSSRHHRDKERHSPFHGNHAAINHSQAPIPKSALVPVIPITKSTGSRFRNSVEGLNQEIEIIIKETGDKEEQLVPQDIPDGHRAPPPLIQRSSSTRSIDTQTPGGAERGSNNSSRSQSVSPTSFLTICNESSEESPCSTEDLVDSRDKENGNNSPLPKYATSPKPNNSYMFKREPPEGCEKVKVFEESLPKPLHEIPAFYCPDKNKVNFIPKSGSAFCLVSILKPLLPTQDLTLKGTTHSLTVSSGMTPSLLQPISMASLSANTDQDRISRGTSTVIPQTSILQQSGRIEEAEG", "length": 567, "header": "tr|A0A8V1A6K3-1|A0A8V1A6K3_CHICK Isoform 1 of Family with sequence similarity 117 member B OS=Gallus gallus OX=9031 GN=FAM117B PE=4 SV=1 CANONICAL=A0A8V1A6K3-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A6K3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6K3/entry#A0A8V1A6K3-1", "sequence": { "sequence": "MSHQRVRRGGSPTPAASPGGGGAAAAGGGAGASGRLQPMRATVPFQLKQQQQHGSPTRSGASAPGGGLARAAAASRSISPTRATPTGGRAGPATAAQTPGGGGSPTRGGGGARGSPPRPHQLPPPPPPPPPPVACGPSPCSSPLPEGSSTAGRVRHPRHSPEQGRSSPERKSPGSPGCKADKSRPPSSSPSSIIRRTSSLDTLAAPYLAGQWPRDNHGQAVPCMRDKATQTESAWAEEYLEKKRSSHKRSASWGSTEQLKEIAKLRQQLQRSKHSSRHHRDKERHSPFHGNHAAINHSQAPIPKSALVPVIPITKSTGSRFRNSVEGLNQEIEIIIKETGDKEEQLVPQDIPDGHRAPPPLIQRSSSTRSIDTQTPGGAERGSNNSSRSQSVSPTSFLTICNESSEESPCSTEDLVDSRDKENGNNSPLPKYATSPKPNNSYMFKREPPEGCEKVKVFEESLPKPLHEIPAFYCPDKNKVNFIPKSGSAFCLVSILKPLLPTQDLTLKGTTHSLTVSSGMTPSLLQPISMASLSANTDQDRISRGTSTVIPQTSILQQSGRIEEAEG", "length": 567, "header": "tr|A0A8V1A6K3-1|A0A8V1A6K3_CHICK Isoform 1 of Family with sequence similarity 117 member B OS=Gallus gallus OX=9031 GN=FAM117B PE=4 SV=1 CANONICAL=A0A8V1A6K3-1" }, "locus": { "chromosome": "7", "start_pos": 11571014, "end_pos": 11547820, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010061545.1", "url": "https://www.ensembl.org/id/ENSGALT00010061545.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038020.1", "url": "https://www.ensembl.org/id/ENSGALP00010038020.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 13, "start_aa": "Thr", "end_pos": 13, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr13", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1M7C4-1", "protein_name": "Family with sequence similarity 117 member B", "gene_name": "FAM117B", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSQRVRRNGSPTPAGSLGGSAVATAGGSGSRLQPMRATVPFQLKQQQQHGSPTRSNGGGGGGNNNGGCCGGASGPSGGGGSGGAPRTASRSTSPTRGGGSAAARTSPTVATQTGASATSTRGTSPTRAAAPGARGSPPRPQPPPPLLGTVSSPCSSPTHLWTGEVSAAPPPARVRHRRRSPEHSRSSPERRSPSAPVCKAGDKTRPPSSSPSSIIRRTSSLDTLAAPYLAGHWPRDGHGQAAPCMRDKATQTESAWAEEYSEKKKGSHKRSASWGSTDQLKEIAKLRQQLQRSKHSSRHHRDKERQSPFHGNHAAINQSQAPVPKSALIPVIPITKSTGSRFRNSVEGLNQEIEIIIKETGEKEEQLIPQDIPDGHRAPPPLAQRSSSTRSTDTQTPGGAERGSNDSSRSQSVSPTSFLTISNEGSEESPCSADDLLVDPRDKENGNNSPLPKYATSPKPNNSYMFKREPPEGCERVKVFEECSPKQLHEIPAFYCPDKNKVNFIPKSGSAFCLVSILKPLLPTPDLTLKGSGHSLTVTTGMTTTLLQPIAVASLSTNTEQDRVSRGTSTVLPPASLLPTPEPIEEAEG", "length": 589 }, "evidence": [ { "id": "A0A8V1A6K3", "url": "https://omabrowser.org/oma/group/A0A8V1A6K3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A5G2R1C2-1", "protein_name": "Family with sequence similarity 117 member B", "gene_name": "FAM117B", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSQRVRRNGSPTPAGSLGGGAVTTAGGSGSRLQPMRATVPFQLKQQQQQHGSPTRSNGGGGGGNNNGGCCGGASGPSGGGGSSGGGAPRTASRSTSPTRGGGSAAARTSPTVATQTGASATSTRGTSPTRGAAPGARGSPPRPQPPPPLLGTVSSPCSSPTHLWTGEVSAAPPPARVRHRRRSPEQSRSSPERRSPSAPVCKAGDKTRPPSSSPSSIIRRTSSLDTLAAPYLAGHWPRDGHGQAAPCMKDKATQTESAWAEEYSEKKKGSHKRSASWGSTDQLKEIAKLRQQLQRSKHSSRHHRDKERQSPFHGNHAAINQCQAPVPKSALIPVIPITKSTGSRFRNSVEGLNQEIEIIIKETGEKEEQLIPQDIPDGHRAPPPLVQRSSSTRSIDTQTPGGAERGSNNSSRSQSVSPTSFLTISNEGSEESPCSADDLLVDPRDKENGNNSPLPKYATSPKPNNSYMFKREPPEGCERVKVFEECSPKQLHEIPAFYCPDKNKVNFIPKSGSAFCLVSILKPLLPTPDLTLKGSVHSLTVTTGMTTTLLQPIAVASLSTNTEQDRVSRGTSTVLPPASLLPPPEPIEEAEG", "length": 592 }, "evidence": [ { "id": "A0A8V1A6K3", "url": "https://omabrowser.org/oma/group/A0A8V1A6K3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0AB32TZJ0-1", "protein_name": "Protein FAM117B isoform X1", "gene_name": "fam117bb", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSQRVRKNGSPTSGVTTGSPIGSPGISAAGVNLLGRLLPMKATVPFQLKTQPQHPLQTRTVLSSSSSGNGKCHSSGAHSRSPTRSLSSSAVSAATSTSSAFITPTAASSSPSPSSSSRTSPIIVVHATNPRSSSSSAHSGVHLGPQCCSPSQQTSCGCSDPSAFTSHLSSSPSSSSPLWSCGHRAKPLQTPEHDRLSPERLSPSSPVCTDKHRLPVAGSWCTTSSNGSIRRTSSLDALTAPYLSGHWPRDASHAPCAPCMRDKSTQTPSAWADECGEKKRGCHKRSASCGSTDQLKEIVKLRQQLQRSKHSSRHHRDKERKSPFNGNHAAFSQSQLLSTCFLEPLFTRLELHCCVQLCSASQVCRRTCQATGQTGNSGKATVSGQLAPIPKSVLISIPISKSSVSRFRNSVEGLNQEIERIIIRDTGDREEQLIPQEVPDGHRAPPPLCQRSIDTQTPLGTATGSNSSSRSQSISPTFLSVPSESCSDSPSPHEDETLADGREKDLALCSPLPKYASSPKPNNSFMFKREPPEGCERVKVFTEETQARPPREIPQFLCPDRNKVNFIPKSGSAFCLVSIPKPLMATQELNNLKNQSSTRLTPEPEPRVPRRTCMLSQQPSGSAPSSCPSES", "length": 631 }, "evidence": [ { "id": "A0A8V1A6K3", "url": "https://omabrowser.org/oma/group/A0A8V1A6K3/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q3U3E2-1", "protein_name": "Protein FAM117B", "gene_name": "Fam117b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSQRVRRNGSPTPAGALAGGAVGPPGGPGSRLQPMRATVPFQLKQQQQHGSPTRGGGGGGNNGGNGGASGPSGGGGSGGPRTASRSTSPTRGGGGSAAARTSPTVATQTGASVTSTRGTSPTRGTAPGARSSPPRPQPPPPLLGTVSSPSSSPTHLWPSEVIAAPPSARVRHRRRSPEQGRPSAEKRSPSAPVCKAGDKTHPPSSSSSSIIRRTSSLDTLAAPYLAGHWPRDIRGQAAPCMRDKATQTESAWAEEYEKKKGSHKRSSSWGSTEQLKEIAKLRQQLQRSKHSSRHHRDKERQSPFHGNHAAINQSQAPAPKSTLVPAGPITKSSGSRFRNSVEGLNQEIEIIIKETGEKEEQLIPQDIPDGHRAPPPLAQRSSSTRSIDTQTPGGADKGSNNSSRSQSVSPTSFLTISNEGSEESPCSADDLLADPRDKENGNNSPLPKYATSPKPNNSYMFKREPPEGCERVKVFEECSPKQLHEIPAFYCPDKNKVNFIPKSGSAFCLVSILKPLLPTPDLTLKGSGHSLTVTTGMTTTLLQPISMASLSTNTEQERVSRGTSTVLPSASLHAPPEPIEEAEG", "length": 584 }, "evidence": [ { "id": "A0A8V1A6K3", "url": "https://omabrowser.org/oma/group/A0A8V1A6K3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6P1L5-1", "protein_name": "Protein FAM117B", "gene_name": "FAM117B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSQRVRRNGSPTPAGSLGGGAVATAGGPGSRLQPMRATVPFQLKQQQQQQHGSPTRSGGGGGGNNNGGCCGGASGPAGGGGGGGPRTASRSTSPTRGGGNAAARTSPTVATQTGASATSTRGTSPTRSAAPGARGSPPRPPPPPPLLGTVSSPSSSPTHLWTGEVSAAPPPARVRHRRRSPEQSRSSPEKRSPSAPVCKAGDKTRQPSSSPSSIIRRTSSLDTLAAPYLAGHWPRDSHGQAAPCMRDKATQTESAWAEEYSEKKKGSHKRSASWGSTDQLKEIAKLRQQLQRSKHSSRHHRDKERQSPFHGNHAAINQCQAPVPKSALIPVIPITKSTGSRFRNSVEGLNQEIEIIIKETGEKEEQLIPQDIPDGHRAPPPLVQRSSSTRSIDTQTPGGADRGSNNSSRSQSVSPTSFLTISNEGSEESPCSADDLLVDPRDKENGNNSPLPKYATSPKPNNSYMFKREPPEGCERVKVFEECSPKQLHEIPAFYCPDKNKVNFIPKSGSAFCLVSILKPLLPTPDLTLKGSGHSLTVTTGMTTTLLQPIAVASLSTNTEQDRVSRGTSTVMPSASLLPPPEPIEEAEG", "length": 589 }, "evidence": [ { "id": "A0A8V1A6K3", "url": "https://omabrowser.org/oma/group/A0A8V1A6K3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 296, "end_pos": 298, "annotation": "n_glycosylation_sequon" }, { "start_pos": 384, "end_pos": 386, "annotation": "n_glycosylation_sequon" }, { "start_pos": 385, "end_pos": 387, "annotation": "n_glycosylation_sequon" }, { "start_pos": 402, "end_pos": 404, "annotation": "n_glycosylation_sequon" }, { "start_pos": 425, "end_pos": 427, "annotation": "n_glycosylation_sequon" }, { "start_pos": 439, "end_pos": 441, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 13 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 296, "end_pos": 298 }, { "start_pos": 384, "end_pos": 386 }, { "start_pos": 385, "end_pos": 387 }, { "start_pos": 402, "end_pos": 404 }, { "start_pos": 425, "end_pos": 427 }, { "start_pos": 439, "end_pos": 441 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A6K4-1", "uniprot_ac": "A0A8V1A6K4", "uniprot_id": "A0A8V1A6K4_CHICK", "mass": { "chemical_mass": 34839.0, "monoisotopic_mass": 34839.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "A0A8V1A6K4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6K4/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A6K4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6K4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6K4", "locus": {} } ], "crossref": [ { "id": "A0A8V1A6K4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A6K4", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR002110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR24171", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24171", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24171:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24171:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24198", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24198", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24198:SF165", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24198:SF165", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00023", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00023", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12796", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12796", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1A6K4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6K4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A6K4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6K4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ABZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABZ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ABZ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABZ8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRNYVSEVNESVRDSRRQLIGYLLERDKVWFEKSYEQCQEERESPGRKRHEGDTKKKGKETQLSGAAKPREHHSDIGIFDTAAKGYLSELEKTLKDNDINALNSSNETLLHVAASQGHLSIMEYLISKGAKLDVMDQKGRIPLHRAAEKGHGDAVKVLLLSAGAKINAVTKEFVTPLHTASQRGNADVALQFLHHKANVNAKDKQSKSPLHFASERGDKTMVEMLLNANADPNAQDKEKKTPLHAAALRGHLKVVKLLLMSGKNKNIDDRNIWRKTIALPSLPAQPHTPAPGWMREMSQPIPIPACLIISLPN", "length": 313, "header": "tr|A0A8V1A6K4-1|A0A8V1A6K4_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1A6K4-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A6K4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6K4/entry#A0A8V1A6K4-1", "sequence": { "sequence": "MRNYVSEVNESVRDSRRQLIGYLLERDKVWFEKSYEQCQEERESPGRKRHEGDTKKKGKETQLSGAAKPREHHSDIGIFDTAAKGYLSELEKTLKDNDINALNSSNETLLHVAASQGHLSIMEYLISKGAKLDVMDQKGRIPLHRAAEKGHGDAVKVLLLSAGAKINAVTKEFVTPLHTASQRGNADVALQFLHHKANVNAKDKQSKSPLHFASERGDKTMVEMLLNANADPNAQDKEKKTPLHAAALRGHLKVVKLLLMSGKNKNIDDRNIWRKTIALPSLPAQPHTPAPGWMREMSQPIPIPACLIISLPN", "length": 313, "header": "tr|A0A8V1A6K4-1|A0A8V1A6K4_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1A6K4-1" }, "locus": { "chromosome": "8", "start_pos": 26029786, "end_pos": 26027261, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065220.1", "url": "https://www.ensembl.org/id/ENSGALT00010065220.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039721.1", "url": "https://www.ensembl.org/id/ENSGALP00010039721.1" } ] } }, { "isoform_ac": "A0A8V1ABZ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6K4/entry#A0A8V1ABZ8-1", "sequence": { "sequence": "MVLLHFALCKYANTATVTMLSIFSCQLGPKEPDKPIPAIQSSASQKHFFPSLPLEEARRSGNQQHFLHMAALKDESSLAKMLLKCGASIDGKDERGQTALSYAVHQGFENTAEVLLEAGANLPSDIMESALFKAVQKNLHGIVAALADRGTDINAYSEIQYTPLLLACETGKAECAEVLIEKGANLGIKTPASDTALHLAVQAGPAYSYSSLFNHFTSKLIPAQRNSE", "length": 228, "header": "tr|A0A8V1ABZ8-1|A0A8V1ABZ8_CHICK Computationally mapped isoform of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1A6K4-1" }, "locus": { "chromosome": "8", "start_pos": 26030575, "end_pos": 26027235, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065242.1", "url": "https://www.ensembl.org/id/ENSGALT00010065242.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039727.1", "url": "https://www.ensembl.org/id/ENSGALP00010039727.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 103, "end_pos": 105, "annotation": "n_glycosylation_sequon" }, { "start_pos": 106, "end_pos": 108, "annotation": "n_glycosylation_sequon" }, { "start_pos": 9, "end_pos": 11, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 103, "end_pos": 105 }, { "start_pos": 106, "end_pos": 108 }, { "start_pos": 9, "end_pos": 11 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"https://www.uniprot.org/uniprotkb/A0A8V1A6L3", "locus": {} } ], "crossref": [ { "id": "A0A8V1A6L3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A6L3", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd16553", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16553", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017907", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017907", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027370", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027370", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038896", "url": 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"UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A938", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A938", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A938-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A938-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AC02", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC02", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AC02-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC02-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRHLLQQPELESLQIQQPSNHSDFSCPICLQTVTLPVETNCGHLFCGSCLITYWKHSPWLGAIICPLCRQKVVVLDNISCEKLHDKPSKQIVHDIRAYNRRFSGQPRPFADYLYDMPLFLTLALRGIFTWGGLMCIFFLRVVVCSFGTVICLSSPFDTMPGPLCRTLGTADDMVVVSLLFICVINICQQIATNRVNMARSAARSMLSES", "length": 209, "header": "tr|A0A8V1A6L3-1|A0A8V1A6L3_CHICK Isoform 1 of RING-type domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1A6L3-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A6L3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6L3/entry#A0A8V1A6L3-1", "sequence": { "sequence": "MRHLLQQPELESLQIQQPSNHSDFSCPICLQTVTLPVETNCGHLFCGSCLITYWKHSPWLGAIICPLCRQKVVVLDNISCEKLHDKPSKQIVHDIRAYNRRFSGQPRPFADYLYDMPLFLTLALRGIFTWGGLMCIFFLRVVVCSFGTVICLSSPFDTMPGPLCRTLGTADDMVVVSLLFICVINICQQIATNRVNMARSAARSMLSES", "length": 209, "header": "tr|A0A8V1A6L3-1|A0A8V1A6L3_CHICK Isoform 1 of RING-type domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1A6L3-1" }, "locus": { "chromosome": "8", "start_pos": 26314598, "end_pos": 26307883, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065252.1", "url": "https://www.ensembl.org/id/ENSGALT00010065252.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039731.1", "url": "https://www.ensembl.org/id/ENSGALP00010039731.1" } ] } }, { "isoform_ac": "A0A8V1A938-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6L3/entry#A0A8V1A938-1", "sequence": { "sequence": "AGQESLQIQQPSNHSDFSCPICLQTVTLPVETNCGHLFCGSCLITYWKHSPWLGAIICPLCRQKVVVLDNISCEKLHDKPSKQIVHDIRAYNRRFSGQPRPFADYLYDMPLFLTLALRGIFTWGGLMCIFFLRVVVCSFGTVICLSSPFDTMPGPLCRTLGTADDMVVVSLLFICVINICQQIATNRVNMARSAARSMLSES", "length": 202, "header": "tr|A0A8V1A938-1|A0A8V1A938_CHICK Computationally mapped isoform of RING-type domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1A6L3-1" }, "locus": { "chromosome": "8", "start_pos": 26323642, "end_pos": 26307883, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065256.1", "url": "https://www.ensembl.org/id/ENSGALT00010065256.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039733.1", "url": "https://www.ensembl.org/id/ENSGALP00010039733.1" } ] } }, { "isoform_ac": "A0A8V1AC02-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6L3/entry#A0A8V1AC02-1", "sequence": { "sequence": "MESLQIQQPSNHSDFSCPICLQTVTLPVETNCGHLFCGSCLITYWKHSPWLGAIICPLCRQKVVVLDNISCEKLHDKPSKQIVHDIRAYNRRFSGQPRPFADYLYDMPLFLTLALRGIFTWGGLMCIFFLRVVVCSFGTVICLSSPFDTMPGPLCRTLGTADDMVVVSLLFICVINICQQIATNRVNMARSAARSMLSES", "length": 200, "header": "tr|A0A8V1AC02-1|A0A8V1AC02_CHICK Computationally mapped isoform of RING-type domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1A6L3-1" }, "locus": { "chromosome": "8", "start_pos": 26316468, "end_pos": 26307883, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065254.1", "url": "https://www.ensembl.org/id/ENSGALT00010065254.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039732.1", "url": "https://www.ensembl.org/id/ENSGALP00010039732.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:100859636", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100859636", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A6L3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6L3" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A6L3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6L3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 20, "end_pos": 22, "annotation": "n_glycosylation_sequon" }, { "start_pos": 77, "end_pos": 79, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1A6L3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6L3" }, { "id": "PS50089", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50089" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RING-type", "eco_id": "ECO_0000259", "start_pos": 26, "end_pos": 69, "start_aa": "Cys", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 20, "end_pos": 22 }, { "start_pos": 77, "end_pos": 79 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A6L7-1", "uniprot_ac": "A0A8V1A6L7", "uniprot_id": "A0A8V1A6L7_CHICK", "mass": { "chemical_mass": 143984.0, "monoisotopic_mass": 143984.0 }, "refseq": { "ac": "XP_422457", "name": "SCL-interrupting locus protein isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_422457" }, "gene_names": [ { "name": "STIL", "type": "recommended", "evidence": [ { "id": "A0A8V1A6L7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6L7" } ] }, { "name": "STIL", "type": "synonym", "evidence": [ { "id": "XP_422457", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_422457" } ] } ], "protein_names": [ { "name": "SCL-interrupting locus protein isoform X2", "type": "synonym", "evidence": [ { "id": "XP_422457", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_422457" } ] }, { "name": "STIL centriolar assembly protein", "type": "synonym", "evidence": [ { "id": "A0A8V1A6L7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6L7/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052539.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_422457.4. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_422457", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_422457" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A6L7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6L7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "STIL", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6L7", "locus": { "chromosome": "8", "start_pos": 21608966, "end_pos": 21627569, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010024669", "url": "https://www.ensembl.org/id/ENSGALG00010024669" } ] } } ], "crossref": [ { "id": "424621", "url": "https://www.ncbi.nlm.nih.gov/gene/424621", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026123", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026123", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057655", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057655", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057731", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057731", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058559", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058559", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:424621", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424621", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1A6L7", "url": "https://www.orthodb.org/?gene=A0A8V1A6L7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15128", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15128", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15128:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15128:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15253", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15253", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25775", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25775", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF26399", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26399", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_422457", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_422457", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1A6L7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6L7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A6L7-1", "url": 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"https://www.ebi.ac.uk/interpro/entry/IPR056897", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056898", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056898", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056899", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056899", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057586", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057586", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058779", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058779", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A6M1", "url": "https://www.orthodb.org/?gene=A0A8V1A6M1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ABH0", "url": "https://www.orthodb.org/?gene=A0A8V1ABH0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AEA5", "url": "https://www.orthodb.org/?gene=A0A8V1AEA5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AGT7", "url": "https://www.orthodb.org/?gene=A0A8V1AGT7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23019", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23019", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23019:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23019:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02368", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02368", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22957", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22957", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22959", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22959", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22962", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22962", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22963", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22963", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22967", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22967", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22969", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22969", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24902", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24902", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24935", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24935", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24991", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24991", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25354", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25354", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF26181", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26181", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF26182", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26182", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF26183", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26183", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF26184", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26184", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-159227", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-159227", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-159230", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-159230", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-159231", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-159231", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-159236", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-159236", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-1855170", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1855170", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-1855196", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1855196", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-1855229", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1855229", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-191859", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-191859", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-3108214", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3108214", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-3232142", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3232142", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-3301854", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3301854", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-4085377", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4085377", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-4551638", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4551638", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-4615885", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4615885", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1A6M1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6M1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A6M1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6M1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ABH0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABH0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ABH0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABH0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AEA5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEA5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AEA5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEA5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGT7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGT7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGT7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGT7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAPPAPRALLLLLLLHRLAASSKLNIPKVLLPFTRGTRVNFTLEASEGCYRWSSTRPEVASIEPADQGERQCSQKAVVQARSSQPTRLTSIIFAEDTMTGQVLRCDAIVDIIHGIQIVSTTRELYLEDSPLELKIQALDSEGNTFSTLAGLVFDWTIVKDTEADGFSDSHNALRILKFLESTYIPPPYISEMEKVAKQGDTILVSGMKTGSSKLKARIQESVYKHVPPAEVRLLILENILLNPAYDVYLLVGTSIKYRVQKIRQGKITELMMPSDQYELQLQNNVLGPEGDPSWPVARLDQETSIVTAMQQGQTNLILGHKSIRMQGVSRLPNSTIYVVNPGYLGFAVHPGDRWVLETGRFYEITIEVYDKSSNKVYLSDNIRINTKLSEEYFEVLKSSLNGSYHYVKAIKKGQTIIDAALTSVVDQDGGVHTLPVPVRNQQDVEIYVPIVLSPSILTFPWQPKAGVYQYTIQAHGGSGNFSWSCSNQAVATVTVKGVMTTGSDIGISIIQAIDVQNPLHYGEMKVYVTEPSGMEFIPCQVEARVGQVLELPLRINGLTNVETGEIVPLSDCSHFDLVVEVENRGVFRPLQGRLKPTADFCSGVRVKAETQGYTTLVVSYTHAHVRLSASITIAAYLPLKTIDPPSVALVTLGSSKDILFEGGPRPWIQEPSKFFRNITAEDEESIGLSLFAPPMSRNNIQHWVQVSCKSLGEQVIALTVGNNPSMTNPFPAVEPAVVKFICAVPSRLTLTPIYGSPQLDLSCPLLQQNKQVVPVSNYRNPVLDLAAYDQHGSKFDNFSSLSVVWESTKSSLANIEPDMPMELTLKDDGSGQRKMHGLQTVLVHHKSGTTAISATATGYQQSHLKAAKVKSPYESLLPVSATIELILVEDVKVSPTDVSIYNHPDVQAELFIKEGSGYFFINTSVASVVSVALEETQGIVLVHPLLPGSVTVMVHDLCLAFPAPAKAEVYVSDIQELYVRVVDKVEIGKTVKAFIRVLDDSKKPFLAKYFAVMDLKLRAASQIVSLVPLGEALDDHTAAFLVHGIAIGQTSLTASVADRRGQRINSAPQQIEVFPPFRLLPRKVTLIIGAMIQITSEGGPQPQSNIIFSISDEKIASVNSTGLIRGVAIGNGTVTGVVQAVDAETGKLVVVSQDKVEVEVVQLTAVRIRAPITRMKTGTQMPVYVMGITSSQTPFSFGNAVPGLTFHWSVTKRDTLDVKTRHSEASFQLPAKYNFAMDVYGRVKGRTGLKVVVKVLDPAANQFYNMARELSDEIQIQVFEKLHLVTPEVETEQILMSPNSFIKLQTNRDRVASLSYRVLDGPDKVPVVKIDERGFLNSGSLIGSSTMEVISQESFGINQTIVAAVKVYPISYLRISMSPILRTQNKEALLALPLGVTLTFTVHFHDNSGDTFHSHNSVLNFATNRDDFVQIGKGATNNTFVIRTVNVGLTLLKVWDAEHSGIADYVPLPVQHAIFPELTDVVVGDVLCLSTLLTNQEGLPGIWSSSSNSVLQIDSKTGVAVAKDSGVATVYYEIPGLLKTYREVLINIPQRTTAMHVSGVKTSLQGVAASKVIVLIGERNKNLQGKCLPAQIEAIAELQPQSIISCHLKFDSDAFDFPARDIFVAEPGFDAISGHYMCSITMHRLTDKQLKHLSMSKTELRVTASIQGSHFSGEQIGTEVPFNPGFYADQTEVLLSNHYPSADVKIFGATEILDTLEVKCGSPTVKAFEKEKSYGLPSYIVYTVSLSDPRVSSQGSLSTALTISSPMTDQTIIIPVTVIYLTDRTSAPVRHGASLFQHFLDSYQVMFFTLFALLAGTAVMIIAYHAIFSQKEQHTHPAFTPRTPPQHSHNSSKLTGLFNSEWIIILTRHMLQQMISGSYFFPTSSTNPKYDCFSHFPLCFRFLCITCAFLQPSVLKQENKPIVHALEH", "length": 1928, "header": "tr|A0A8V1A6M1-1|A0A8V1A6M1_CHICK Isoform 1 of Nucleoporin 210 OS=Gallus gallus OX=9031 GN=NUP210 PE=1 SV=1 CANONICAL=A0A8V1A6M1-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A6M1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6M1/entry#A0A8V1A6M1-1", "sequence": { "sequence": "MAPPAPRALLLLLLLHRLAASSKLNIPKVLLPFTRGTRVNFTLEASEGCYRWSSTRPEVASIEPADQGERQCSQKAVVQARSSQPTRLTSIIFAEDTMTGQVLRCDAIVDIIHGIQIVSTTRELYLEDSPLELKIQALDSEGNTFSTLAGLVFDWTIVKDTEADGFSDSHNALRILKFLESTYIPPPYISEMEKVAKQGDTILVSGMKTGSSKLKARIQESVYKHVPPAEVRLLILENILLNPAYDVYLLVGTSIKYRVQKIRQGKITELMMPSDQYELQLQNNVLGPEGDPSWPVARLDQETSIVTAMQQGQTNLILGHKSIRMQGVSRLPNSTIYVVNPGYLGFAVHPGDRWVLETGRFYEITIEVYDKSSNKVYLSDNIRINTKLSEEYFEVLKSSLNGSYHYVKAIKKGQTIIDAALTSVVDQDGGVHTLPVPVRNQQDVEIYVPIVLSPSILTFPWQPKAGVYQYTIQAHGGSGNFSWSCSNQAVATVTVKGVMTTGSDIGISIIQAIDVQNPLHYGEMKVYVTEPSGMEFIPCQVEARVGQVLELPLRINGLTNVETGEIVPLSDCSHFDLVVEVENRGVFRPLQGRLKPTADFCSGVRVKAETQGYTTLVVSYTHAHVRLSASITIAAYLPLKTIDPPSVALVTLGSSKDILFEGGPRPWIQEPSKFFRNITAEDEESIGLSLFAPPMSRNNIQHWVQVSCKSLGEQVIALTVGNNPSMTNPFPAVEPAVVKFICAVPSRLTLTPIYGSPQLDLSCPLLQQNKQVVPVSNYRNPVLDLAAYDQHGSKFDNFSSLSVVWESTKSSLANIEPDMPMELTLKDDGSGQRKMHGLQTVLVHHKSGTTAISATATGYQQSHLKAAKVKSPYESLLPVSATIELILVEDVKVSPTDVSIYNHPDVQAELFIKEGSGYFFINTSVASVVSVALEETQGIVLVHPLLPGSVTVMVHDLCLAFPAPAKAEVYVSDIQELYVRVVDKVEIGKTVKAFIRVLDDSKKPFLAKYFAVMDLKLRAASQIVSLVPLGEALDDHTAAFLVHGIAIGQTSLTASVADRRGQRINSAPQQIEVFPPFRLLPRKVTLIIGAMIQITSEGGPQPQSNIIFSISDEKIASVNSTGLIRGVAIGNGTVTGVVQAVDAETGKLVVVSQDKVEVEVVQLTAVRIRAPITRMKTGTQMPVYVMGITSSQTPFSFGNAVPGLTFHWSVTKRDTLDVKTRHSEASFQLPAKYNFAMDVYGRVKGRTGLKVVVKVLDPAANQFYNMARELSDEIQIQVFEKLHLVTPEVETEQILMSPNSFIKLQTNRDRVASLSYRVLDGPDKVPVVKIDERGFLNSGSLIGSSTMEVISQESFGINQTIVAAVKVYPISYLRISMSPILRTQNKEALLALPLGVTLTFTVHFHDNSGDTFHSHNSVLNFATNRDDFVQIGKGATNNTFVIRTVNVGLTLLKVWDAEHSGIADYVPLPVQHAIFPELTDVVVGDVLCLSTLLTNQEGLPGIWSSSSNSVLQIDSKTGVAVAKDSGVATVYYEIPGLLKTYREVLINIPQRTTAMHVSGVKTSLQGVAASKVIVLIGERNKNLQGKCLPAQIEAIAELQPQSIISCHLKFDSDAFDFPARDIFVAEPGFDAISGHYMCSITMHRLTDKQLKHLSMSKTELRVTASIQGSHFSGEQIGTEVPFNPGFYADQTEVLLSNHYPSADVKIFGATEILDTLEVKCGSPTVKAFEKEKSYGLPSYIVYTVSLSDPRVSSQGSLSTALTISSPMTDQTIIIPVTVIYLTDRTSAPVRHGASLFQHFLDSYQVMFFTLFALLAGTAVMIIAYHAIFSQKEQHTHPAFTPRTPPQHSHNSSKLTGLFNSEWIIILTRHMLQQMISGSYFFPTSSTNPKYDCFSHFPLCFRFLCITCAFLQPSVLKQENKPIVHALEH", "length": 1928, "header": "tr|A0A8V1A6M1-1|A0A8V1A6M1_CHICK Isoform 1 of Nucleoporin 210 OS=Gallus gallus OX=9031 GN=NUP210 PE=1 SV=1 CANONICAL=A0A8V1A6M1-1" }, "locus": { "chromosome": "12", "start_pos": 5861421, "end_pos": 5803484, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067829.1", "url": "https://www.ensembl.org/id/ENSGALT00010067829.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041572.1", "url": "https://www.ensembl.org/id/ENSGALP00010041572.1" } ] } }, { "isoform_ac": "A0A8V1ABH0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6M1/entry#A0A8V1ABH0-1", "sequence": { "sequence": "MKHPSLHPSVFIHCPSYWRNTFSTLAGLVFDWTIVKDTEADGFSDSHNALRILKFLESTYIPPPYISEMEKVAKQGDTILVSGMKTGSSKLKARIQESVYKHVPPAEVRLLILENILLNPAYDVYLLVGTSIKYRVQKIRQGKITELMMPSDQYELQLQNNVLGPEGDPSWPVARLDQETSIVTAMQQGQTNLILGHKSIRMQGVSRLPNSTIYVVNPGYLGFAVHPGDRWVLETGRFYEITIEVYDKSSNKVYLSDNIRINTKLSEEYFEVLKSSLNGSYHYVKAIKKGQTIIDAALTSVVDQDGGVHTLPVPVRNQQDVEIYVPIVLSPSILTFPWQPKAGVYQYTIQAHGGSGNFSWSCSNQAVATVTVKGVMTTGSDIGISIIQAIDVQNPLHYGEMKVYVTEPSGMEFIPCQVEARVGQVLELPLRINGLTNVETGEIVPLSDCSHFDLVVEVENRGVFRPLQGRLKPTADFCSGVRVKAETQGYTTLVVSYTHAHVRLSASITIAAYLPLKTIDPPSVALVTLGSSKDILFEGGPRPWIQEPSKFFRNITAEDEESIGLSLFAPPMSRNNIQHWVQVSCKSLGEQVIALTVGNNPSMTNPFPAVEPAVVKFICAVPSRLTLTPIYGSPQLDLSCPLLQQNKQVVPVSNYRNPVLDLAAYDQHGSKFDNFSSLSVVWESTKSSLANIEPDMPMELTLKDDGSGQRKMHGLQTVLVHHKSGTTAISATATGYQQSHLKAAKVKSPYESLLPVSATIELILVEDVKVSPTDVSIYNHPDVQAELFIKEGSGYFFINTSVASVVSVALEETQGIVLVHPLLPGSVTVMVHDLCLAFPAPAKAEVYVSDIQELYVRVVDKVEIGKTVKAFIRVLDDSKKPFLAKYFAVMDLKLRAASQIVSLVPLGEALDDHTAAFLVHGIAIGQTSLTASVADRRGQRINSAPQQIEVFPPFRLLPRKVTLIIGAMIQITSEGGPQPQSNIIFSISDEKIASVNSTGLIRGVAIGNGTVTGVVQAVDAETGKLVVVSQDKVEVEVVQLTAVRIRAPITRMKTGTQMPVYVMGITSSQTPFSFGNAVPGLTFHWSVTKRDTLDVKTRHSEASFQLPAKYNFAMDVYGRVKGRTGLKVVVKVLDPAANQFYNMARELSDEIQIQVFEKLHLVTPEVETEQILMSPNSFIKLQTNRDRVASLSYRVLDGPDKVPVVKIDERGFLNSGSLIGSSTMEVISQESFGINQTIVAAVKVYPISYLRISMSPILRTQNKEALLALPLGVTLTFTVHFHDNSGDTFHSHNSVLNFATNRDDFVQIGKGATNNTFVIRTVNVGLTLLKVWDAEHSGIADYVPLPVQHAIFPELTDVVVGDVLCLSTLLTNQEGLPGIWSSSSNSVLQIDSKTGVAVAKDSGVATVYYEIPGLLKTYREVLINIPQRTTAMHVSGVKTSLQGVAASKVIVLIGERNKNLQGKCLPAQIEAIAELQPQSIISCHLKFDSDAFDFPARDIFVAEPGFDAISGHYMCSITMHRLTDKQLKHLSMSKTELRVTASIQGSHFSGEQIGTEVPFNPGFYADQTEVLLSNHYPSADVKIFGATEILDTLEVKCGSPTVKAFEKEKSYGLPSYIVYTVSLSDPRVSSQGSLSTALTISSPMTDQTIIIPVTVIYLTDRTSAPVRHGASLFQHFLDSYQVMFFTLFALLAGTAVMIIAYHAIFSQKEQHTHPAFTPRTPPQHSHNSFSASPVLSFSPQSSSRKTSPSSTLWSTDYGSR", "length": 1760, "header": "tr|A0A8V1ABH0-1|A0A8V1ABH0_CHICK Computationally mapped isoform of Nucleoporin 210 OS=Gallus gallus OX=9031 GN=NUP210 PE=1 SV=1 CANONICAL=A0A8V1A6M1-1" }, "locus": { "chromosome": "12", "start_pos": 5851591, "end_pos": 5803468, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067826.1", "url": "https://www.ensembl.org/id/ENSGALT00010067826.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041569.1", "url": "https://www.ensembl.org/id/ENSGALP00010041569.1" } ] } }, { "isoform_ac": "A0A8V1AEA5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6M1/entry#A0A8V1AEA5-1", "sequence": { "sequence": "MAPPAPRALLLLLLLHRLAASSKLNIPKVLLPFTRGTRVNFTLEASEGCYRWSSTRPEVASIEPADQGERQCSQKAVVQARSSQPTRLTSIIFAEDTMTGQVLRCDAIVDIIHGIQIVSTTRELYLEDSPLELKIQALDSEGNTFSTLAGLVFDWTIVKDTEADGFSDSHNALRILKFLESTYIPPPYISEMEKVAKQGDTILVSGMKTGSSKLKARIQESVYKHVPPAEVRLLILENILLNPAYDVYLLVGTSIKYRVQKIRQGKITELMMPSDQYELQLQNNVLGPEGDPSWPVARLDQETSIVTAMQQGQTNLILGHKSIRMQGVSRLPNSTIYVVNPGYLGFAVHPGDRWVLETGRFYEITIEVYDKSSNKVYLSDNIRINTKLSEEYFEVLKSSLNGSYHYVKAIKKGQTIIDAALTSVVDQDGGVHTLPVPVRNQQDVEIYVPIVLSPSILTFPWQPKAGVYQYTIQVYVTEPSGMEFIPCQVEARVGQVLELPLRINGLTNVETGEIVPLSDCSHFDLVVEVENRGVFRPLQGRLKPTADFCSGVRVKAETQGYTTLVVSYTHAHVRLSASITIAAYLPLKTIDPPSVALVTLGSSKDILFEGGPRPWIQEPSKFFRNITAEDEESIGLSLFAPPMSRNNIQHWVQVSCKSLGEQVIALTVGNNPSMTNPFPAVEPAVVKFICAVPSRLTLTPIYGSPQLDLSCPLLQQNKQVVPVSNYRNPVLDLAAYDQHGSKFDNFSSLSVVWESTKSSLANIEPDMPMELTLKDDGSGQRKMHGLQTVLVHHKSGTTAISATATGYQQSHLKAAKVKSPYESLLPVSATIELILVEDVKVSPTDVSIYNHPDVQAELFIKEGSGYFFINTSVASVVSVALEETQGIVLVHPLLPGSVTVMVHDLCLAFPAPAKAEVYVSDIQELYVRVVDKVEIGKTVKAFIRVLDDSKKPFLAKYFAVMDLKLRAASQIVSLVPLGEALDDHTAAFLVHGIAIGQTSLTASVADRRGQRINSAPQQIEVFPPFRLLPRKVTLIIGAMIQITSEGGPQPQSNIIFSISDEKIASVNSTGLIRGVAIGNGTVTGVVQAVDAETGKLVVVSQDKVEVEVVQLTAVRIRAPITRMKTGTQMPVYVMGITSSQTPFSFGNAVPGLTFHWSVTKRDTLDVKTRHSEASFQLPAKYNFAMDVYGRVKGRTGLKVVVKVLDPAANQFYNMARELSDEIQIQVFEKLHLVTPEVETEQILMSPNSFIKLQTNRDRVASLSYRVLDGPDKVPVVKIDERGFLNSGSLIGSSTMEVISQESFGINQTIVAAVKVYPISYLRISMSPILRTQNKEALLALPLGVTLTFTVHFHDNSGDTFHSHNSVLNFATNRDDFVQIGKGATNNTFVIRTVNVGLTLLKVWDAEHSGIADYVPLPVQHAIFPELTDVVVGDVLCLSTLLTNQEGLPGIWSSSSNSVLQIDSKTGVAVAKDSGVATVYYEIPGLLKTYREVLINIPQRTTAMHVSGVKTSLQGVAASKVIVLIGERNKNLQGKCLPAQIEAIAELQPQSIISCHLKFDSDAFDFPARDIFVAEPGFDAISGHYMCSITMHRLTDKQLKHLSMSKTELRVTASIQGSHFSGEQIGTEVPFNPGFYADQTEVLLSNHYPSADVKIFGATEILDTLEVKCGSPTVKAFEKEKSYGLPSYIVYTVSLSDPRVSSQGSLSTALTISSPMTDQTIIIPVTVIYLTDRTSAPVRHGASLFQHFLDSYQVMFFTLFALLAGTAVMIIAYHAIFSQKEQHTHPAFTPRTPPQHSHNSFSASPVLSFSPQSSSRKTSPSSTLWSTDYGSR", 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"https://www.reactome.org/PathwayBrowser/#R-GGA-4551638", "resource": "Reactome", "description": "SUMOylation of chromatin organization proteins" }, { "id": "R-GGA-4615885", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4615885", "resource": "Reactome", "description": "SUMOylation of DNA replication proteins" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nuclear pore", "id": "GO:0005643", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005643", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A6M1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6M1" } ], "pmid": "" }, { "name": "nuclear membrane", "id": "GO:0031965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031965", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A6M1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6M1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1119, 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"reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A6P0-1", "uniprot_ac": "A0A8V1A6P0", "uniprot_id": "A0A8V1A6P0_CHICK", "mass": { "chemical_mass": 16710.0, "monoisotopic_mass": 16710.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Reverse transcriptase domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8V1A6P0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6P0/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], 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Classification", "Other" ] }, { "id": "A0A8V1A6P0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6P0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A6P0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6P0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSGVPQGSVLGPVLFNIFINYIDDGIECTLSKFADDTKLSGVVDTEEGMDGIQRDLNRLERWAQVNLMGFNTAKCRVLHLGQRNLRHLYRLEGAVLESSSAEKDLGVLMDDKLNMSQQCALAARKANGILGSIMRGVASRDREVNVLSTLLL", "length": 152, "header": "tr|A0A8V1A6P0-1|A0A8V1A6P0_CHICK Isoform 1 of Reverse transcriptase domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1A6P0-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A6P0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6P0/entry#A0A8V1A6P0-1", "sequence": { "sequence": "MSGVPQGSVLGPVLFNIFINYIDDGIECTLSKFADDTKLSGVVDTEEGMDGIQRDLNRLERWAQVNLMGFNTAKCRVLHLGQRNLRHLYRLEGAVLESSSAEKDLGVLMDDKLNMSQQCALAARKANGILGSIMRGVASRDREVNVLSTLLL", "length": 152, "header": "tr|A0A8V1A6P0-1|A0A8V1A6P0_CHICK Isoform 1 of Reverse transcriptase domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1A6P0-1" }, "locus": { "chromosome": "1", "start_pos": 75493574, "end_pos": 75493119, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010060251.1", "url": "https://www.ensembl.org/id/ENSGALT00010060251.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010037011.1", "url": "https://www.ensembl.org/id/ENSGALP00010037011.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 114, "end_pos": 116, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1A6P0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6P0" }, { "id": "PS50878", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50878" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Reverse transcriptase", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 96, "start_aa": "Met", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 114, "end_pos": 116 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A6P7-1", "uniprot_ac": "A0A8V1A6P7", "uniprot_id": "A0A8V1A6P7_CHICK", "mass": { "chemical_mass": 45914.0, "monoisotopic_mass": 45914.0 }, "refseq": { "ac": "XP_015135512", "name": "tuftelin isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015135512" }, "gene_names": [ { "name": "TUFT1", "type": "recommended", "evidence": [ { "id": "A0A8V1A6P7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6P7" } ] }, { "name": "TUFT1", "type": "synonym", "evidence": [ { "id": "XP_015135512", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015135512" } ] } ], "protein_names": [ { "name": "Tuftelin 1", "type": "synonym", "evidence": [ { "id": "A0A8V1A6P7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6P7/entry#names_and_taxonomy" } ] }, { "name": "tuftelin isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015135512", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015135512" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052556.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 1, 2022 this sequence version replaced XP_015135512.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015135512", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015135512" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A6P7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6P7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TUFT1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6P7", "locus": { "chromosome": "25", "start_pos": 2794581, "end_pos": 2781562, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027994", "url": "https://www.ensembl.org/id/ENSGALG00010027994" } ] } } ], "crossref": [ { "id": "A0A8V1A6P7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A6P7", "database": "AlphaFoldDB", "categories": [] }, { "id": "101749610", "url": "https://www.ncbi.nlm.nih.gov/gene/101749610", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR051375", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051375", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:101749610", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:101749610", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HMEHFLA", "url": "https://omabrowser.org/oma/group/HMEHFLA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A6P7", "url": "https://www.orthodb.org/?gene=A0A8V1A6P7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ABJ1", "url": "https://www.orthodb.org/?gene=A0A8V1ABJ1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AED2", "url": "https://www.orthodb.org/?gene=A0A8V1AED2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AIQ0", "url": "https://www.orthodb.org/?gene=A0A8V1AIQ0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23171", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23171", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23171:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23171:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "XP_015135512", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015135512", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1A6P7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6P7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A6P7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6P7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ABJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABJ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ABJ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABJ1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AED2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AED2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AED2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AED2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AIQ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIQ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AIQ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIQ0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRCGAAVGAMNGAMNGVRGWCAVLDVRPHGENPESVKVLRLTLPNELPGERREQAKQKPVGKAFAMVANRSSNGHALASERIKSNDGDEEIIKVYLKARAEGSANHEEHVSQLKSEVRHIQEARSFLKKLREDLSSKLESRQGDKEHTQVVLEEQNGSWLHPERLRAEPWEEQDEDCSGDDVEKMRQTARRLFTRLQEAEKCHQLEKKDLERTVSRYREEAEQTSCALRRAERSVVEKELQVDELQRLLAGMEKEHRTLLLKMKDSEAELARLRSVEGDKLAEQDRSAKLEKEVAMLREKIHHLDDMLKSQQRKVRQMIEQLQNSKTVIQAKDAVIQELKEKVAYLEAENLEMHDRIEHLIEKQVSRGGHSSRARSKSEYVSSKRLMGPKPLPLIRVVET", "length": 400, "header": "tr|A0A8V1A6P7-1|A0A8V1A6P7_CHICK Isoform 1 of Tuftelin 1 OS=Gallus gallus OX=9031 GN=TUFT1 PE=4 SV=1 CANONICAL=A0A8V1A6P7-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A6P7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6P7/entry#A0A8V1A6P7-1", "sequence": { "sequence": "MRCGAAVGAMNGAMNGVRGWCAVLDVRPHGENPESVKVLRLTLPNELPGERREQAKQKPVGKAFAMVANRSSNGHALASERIKSNDGDEEIIKVYLKARAEGSANHEEHVSQLKSEVRHIQEARSFLKKLREDLSSKLESRQGDKEHTQVVLEEQNGSWLHPERLRAEPWEEQDEDCSGDDVEKMRQTARRLFTRLQEAEKCHQLEKKDLERTVSRYREEAEQTSCALRRAERSVVEKELQVDELQRLLAGMEKEHRTLLLKMKDSEAELARLRSVEGDKLAEQDRSAKLEKEVAMLREKIHHLDDMLKSQQRKVRQMIEQLQNSKTVIQAKDAVIQELKEKVAYLEAENLEMHDRIEHLIEKQVSRGGHSSRARSKSEYVSSKRLMGPKPLPLIRVVET", "length": 400, "header": "tr|A0A8V1A6P7-1|A0A8V1A6P7_CHICK Isoform 1 of Tuftelin 1 OS=Gallus gallus OX=9031 GN=TUFT1 PE=4 SV=1 CANONICAL=A0A8V1A6P7-1" }, "locus": { "chromosome": "25", "start_pos": 2793535, "end_pos": 2781761, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067854.1", "url": "https://www.ensembl.org/id/ENSGALT00010067854.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041597.1", "url": "https://www.ensembl.org/id/ENSGALP00010041597.1" } ] } }, { "isoform_ac": "A0A8V1ABJ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6P7/entry#A0A8V1ABJ1-1", "sequence": { "sequence": "MSGPGVGEESVKVLRLTLPNELPGERREQAKQKPVGKAFAMVANRSSNGHALASERIKSNDGDEEIIKVYLKARAEGSANHEEHVSQLKSEVRHIQEARSFLKKLREDLSSKLESRQGDKEHTQVVLEEQNGSWLHPERLRAEPWEEQDEDCSGDDVEKMRQTARRLFTRLQEAEKCHQLEKKDLERTVSRYREEAEQTSCALRRAERSVVEKELQVDELQRLLAGMEKEHRTLLLKMKDSEAELARLRSVEGDKLAEQDRSAKLEKEVAMLREKIHHLDDMLKSQQRKVRQMIEQLQNSKTVIQAKDAVIQELKEKVAYLEAENLEMHDRIEHLIEKQVSRGGHSSRARSKSEYVSSKRLMGPKPLPLIRVVET", "length": 375, "header": "tr|A0A8V1ABJ1-1|A0A8V1ABJ1_CHICK Computationally mapped isoform of Tuftelin 1 OS=Gallus gallus OX=9031 GN=TUFT1 PE=4 SV=1 CANONICAL=A0A8V1A6P7-1" }, "locus": { "chromosome": "25", "start_pos": 2793535, "end_pos": 2784567, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067851.1", "url": "https://www.ensembl.org/id/ENSGALT00010067851.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041594.1", "url": "https://www.ensembl.org/id/ENSGALP00010041594.1" } ] } }, { "isoform_ac": "A0A8V1AED2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6P7/entry#A0A8V1AED2-1", "sequence": { "sequence": "MNGAMNGVRGWCAVLDVRPHGENPESVKVLRLTLPNELPGERREQAKQKPVGKAFAMVANRSSNGHALASERIKSNDGDEEIIKVYLKARAEGSANHEEHVSQLKSEVRHIQEDEDCSGDDVEKMRQTARRLFTRLQEAEKCHQLEKKDLERTVSRYREEAEQTSCALRRAERSVVEKELQVDELQRLLAGMEKEHRTLLLKMKDSEAELARLRSVEGDKLAEQDRSAKLEKEVAMLREKIHHLDDMLKSQQRKVRQMIEQLQNSKTVIQAKDAVIQELKEKVAYLEAENLEMHDRIEHLIEKQVSRGGHSSRARSKSEYVSSKRLMGPKPLPLIRVVET", "length": 340, "header": "tr|A0A8V1AED2-1|A0A8V1AED2_CHICK Computationally mapped isoform of Tuftelin 1 OS=Gallus gallus OX=9031 GN=TUFT1 PE=4 SV=1 CANONICAL=A0A8V1A6P7-1" }, "locus": { "chromosome": "25", "start_pos": 2793535, "end_pos": 2781788, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067853.1", "url": "https://www.ensembl.org/id/ENSGALT00010067853.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041596.1", "url": "https://www.ensembl.org/id/ENSGALP00010041596.1" } ] } }, { "isoform_ac": "A0A8V1AIQ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6P7/entry#A0A8V1AIQ0-1", "sequence": { "sequence": "MRCGAAVGAMNGAMNGVRGWCAVLDVRPHGENPESVKVLRLTLPNELPGERREQAKQKPVGKAFAMVANRSSNGHALASERIKSNDGDEEIIKVYLKARAEGSANHEEHVSQLKSEVRHIQEVVLEEQNGSWLHPERLRAEPWEEQDEDCSGDDVEKMRQTARRLFTRLQEAEKCHQLEKKDLERTVSRYREEAEQTSCALRRAERSVVEKELQVDELQRLLAGMEKEHRTLLLKMKDSEAELARLRSVEGDKLAEQDRSAKLEKEVAMLREKIHHLDDMLKSQQRKVRQMIEQLQNSKTVIQAKDAVIQELKEKVAYLEAENLEMHDRIEHLIEKQVSRGGHSSRARSKSEYVSSKRLMGPKPLPLIRVVET", "length": 373, "header": "tr|A0A8V1AIQ0-1|A0A8V1A6P7_CHICK Computationally mapped isoform of Tuftelin 1 OS=Gallus gallus OX=9031 GN=TUFT1 PE=4 SV=1 CANONICAL=A0A8V1A6P7-1" }, "locus": { "chromosome": "25", "start_pos": 2793535, "end_pos": 2781761, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067855.1", "url": "https://www.ensembl.org/id/ENSGALT00010067855.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041598.1", "url": "https://www.ensembl.org/id/ENSGALP00010041598.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:101749610", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:101749610", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2K7T4-1", "protein_name": "Tuftelin 1", "gene_name": "Tuft1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNGTRSWCTLVDVHPESQTAESVDILRLPLQSELTGDELEHIAQKAGKKTYAMVSGHSSGHSLASELVESHDGHEEIIKVYLKGRSGDKMIHEKNINQLKSEVQYIQEARNCLQKLREDISSKLDRSPGGPLHQQEIQVVLEKPNGFSQSPMTLYSSPPEVDPSMSEDVESLKKTVQGLLAKLREAEQRHQSDRVAFEVTLSRYQREAEQSNVALQREEDRVEQKAAEIGELQSRLLGMEAEHQALLVKVREGDMALEELRIKNADCQAEREKSASLEKEVAGFREKIHHLDDMLKSQQRKVRQMIEQLQNSKAVIQSKDATIQELKEKIAYLEAENLEMHDRMEHLIEKQVSHGNFSTQTRAKTENLGSVRISKPPSPKPLPLIRVVET", "length": 390 }, "evidence": [ { "id": "A0A8V1A6P7", "url": "https://omabrowser.org/oma/group/A0A8V1A6P7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A3Q1MGN7-1", "protein_name": "Tuftelin 1", "gene_name": "TUFT1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNGTRNWCTLVDVHPEGQTAAGRKTYAMVSSRSTSHSLASELVESNDGHEEIIKVYLKGRSGDKMIHEKNINQLKSEVQYIQEARNCLQKLREDISSKLDRDPGDSVHKQEIQVVLEKPNGLSEGPLTTYSSPPEVDTHINEDVESLRKTVQDLLVKLQEAERQHQSDCSAFKVTLSQYQREAKQSQVALQRAEDRAEQKEAEVGELQRRLQGMETEYQAILAKVREGETALEELRSKNVDCQAEQEKAANLEKEVAGLREKIHHLDDMLKSQQRKVRQMIEQLQNSKAVIQSKDTTIQELKEKIAYLEAENLEMHDRMEHLIEKQISHGNFSTQNRAKTENLGSIRISKPPSPKPMPLIRVVET", "length": 365 }, "evidence": [ { "id": "A0A8V1A6P7", "url": "https://omabrowser.org/oma/group/A0A8V1A6P7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A4X1W2Q2-1", "protein_name": "Tuftelin 1", "gene_name": "TUFT1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MMNGTRSWCTLVDVHPEAQTSGSVDILRLTLQSELTGDELERIAQKAGRKTYAMVSGRSTGHSLASELVESNDGHEEIIKVYLKGRSGDKMIHEKNINQLKSEVQYIQEARNSLQKLREDISSKLDKDPGASLHQQEIQVVLEKPNGFSSSPSTPPPPPNSRTPEVDTFVNEDVESLRKTVQDLLVQLQEAERQHQSERVDFEATLSRYQREAEQSHVALQRAEDRVEQKEAEVEELQKRLLGMETEHQALLAKVREGETALEELRGKNSDCRAEQEKAANLEKEVAGLREKIHHLDDMLKSQQRKVRQMIEQLQNSKTVIQSKDTAIQELKEKIAYLEAENLEMHDRMEHLIEKQISHGNFSTQNRAKTENPGSVRISKPPSPKPMPLIRVVET", "length": 395 }, "evidence": [ { "id": "A0A8V1A6P7", "url": "https://omabrowser.org/oma/group/A0A8V1A6P7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3H308-1", "protein_name": "Tuftelin isoform X1", "gene_name": "Tuft1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MNGTRNWCTLVDVHPEGQTAGSVDILRLTLQSELTGDELEHIAQKAGRNTYAMVSDRSSGHSLASELVESHDGHEEIIKVYLKGRSGDRMIHEKSINQLKSEVQYIQEARNCLQKLREDISSKLDRNPGDPLQQQEIQVVLEKPNGFGQGPMTLYSSPPEADTCMTDDVESLKKTVQGLLAKLQEAERRHQSDRVAFEVTLKQYQREAEQSNVALQREEDRVEQKSAEVGELQRRLLGMETEHQALLSKVREGEMALEELRIKNADCQAEREKAAALEKEVAGFREKIHHLDDMLKSQQRKVRQMIEQLQNSKAVIQSKDTTIQELKEKIAYLEAENLEMHDRMEHLIEKQVSHGNFSTQTRAKTENLGSVRISKPPSPKPMPLIRVVET", "length": 390 }, "evidence": [ { "id": "A0A8V1A6P7", "url": "https://omabrowser.org/oma/group/A0A8V1A6P7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "O08970-1", "protein_name": "Tuftelin", "gene_name": "Tuft1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNGTRNWCTLVDVHPESQTAGSVDILRLTLQSELTGDELEHIAQKAGRKTYAMMPGHSSGHSLASELVESHDGHEEIIKVYLKGRSGDKMTHEKNIDQLKSEVQYIQEARNCLQKLREDISSKLDRSPGDPLRQQEIQVVLEKPNGFSQSPMTLYSSPPEVDPSMSEDVESLKKTVQELLVKLREAERRHQSDRVAFEVTLSRYQREAEQSNVALQREEDRVEQKAAEIEELQRRLLGMEAEHQALLVKVREGEMALEELRIKNADCQTEREKSAALEKEVAGFREKIHHLDDMLKSQQRKVRQMIEQLQNSKAVIQSKDATIQELKEKIAYLEAENLEMHDRMEHLIEKQVSHGNFSTQARAKTENLGSVRISKPPSPKPMPLIRVVET", "length": 390 }, "evidence": [ { "id": "A0A8V1A6P7", "url": "https://omabrowser.org/oma/group/A0A8V1A6P7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NNX1-1", "protein_name": "Tuftelin", "gene_name": "TUFT1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNGTRNWCTLVDVHPEDQAAGSVDILRLTLQGELTGDELEHIAQKAGRKTYAMVSSHSAGHSLASELVESHDGHEEIIKVYLKGRSGDKMIHEKNINQLKSEVQYIQEARNCLQKLREDISSKLDRNLGDSLHRQEIQVVLEKPNGFSQSPTALYSSPPEVDTCINEDVESLRKTVQDLLAKLQEAKRQHQSDCVAFEVTLSRYQREAEQSNVALQREEDRVEQKEAEVGELQRRLLGMETEHQALLAKVREGEVALEELRSNNADCQAEREKAATLEKEVAGLREKIHHLDDMLKSQQRKVRQMIEQLQNSKAVIQSKDATIQELKEKIAYLEAENLEMHDRMEHLIEKQISHGNFSTQARAKTENPGSIRISKPPSPKPMPVIRVVET", "length": 390 }, "evidence": [ { "id": "A0A8V1A6P7", "url": "https://omabrowser.org/oma/group/A0A8V1A6P7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "I band", "id": "GO:0031674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031674", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A6P7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6P7" } ], "pmid": "" }, { "name": "RNA polymerase II, core complex", "id": "GO:0005665", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005665", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A6P7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6P7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "structural constituent of skin epidermis", "id": "GO:0030280", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030280", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A6P7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6P7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 156, "end_pos": 158, "annotation": "n_glycosylation_sequon" }, { "start_pos": 69, "end_pos": 71, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 156, "end_pos": 158 }, { "start_pos": 69, "end_pos": 71 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A6Q0-1", "uniprot_ac": "A0A8V1A6Q0", "uniprot_id": "A0A8V1A6Q0_CHICK", "mass": { "chemical_mass": 24207.0, "monoisotopic_mass": 24207.0 }, "refseq": { "ac": "NP_001273177", "name": "protein C11orf74 homolog", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001273177" }, "gene_names": [ { "name": "C11orf74", "type": "recommended", "evidence": [ { "id": "A0A8V1A6Q0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6Q0" } ] }, { "name": "C11orf74", "type": "synonym", "evidence": [ { "id": "NP_001273177", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001273177" } ] }, { "name": "C5H11orf74", "type": "synonym", "evidence": [ { "id": "NP_001273177", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001273177" } ] } ], "protein_names": [ { "name": "C11orf74 homolog", "type": "synonym", "evidence": [ { "id": "A0A8V1A6Q0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6Q0/entry#names_and_taxonomy" } ] }, { "name": "chromosome 5 C11orf74 homolog", "type": "synonym", "evidence": [ { "id": "NP_001273177", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001273177" } ] }, { "name": "protein C11orf74 homolog", "type": "synonym", "evidence": [ { "id": "NP_001273177", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001273177" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: CO635604.1, HAEK01025004.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000214.1. On Sep 23, 2021 this sequence version replaced NP_001273177.1. Transcript Variant: This variant (1) encodes a protein. Sequence Note: This RefSeq record was created from transcript data from different strains because no single transcript from the same strain was available for the full length of the gene. The extent of this transcript is supported by transcript alignments and orthologous data.", "evidence": [ { "database": "RefSeq", "id": "NP_001273177", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001273177" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A6Q0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6Q0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "C11orf74", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6Q0", "locus": { "chromosome": "5", "start_pos": 19097740, "end_pos": 19057090, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010025248", "url": "https://www.ensembl.org/id/ENSGALG00010025248" } ] } } ], "crossref": [ { "id": "A0A8V1A6Q0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A6Q0", "database": "AlphaFoldDB", "categories": [] }, { "id": "423166", "url": "https://www.ncbi.nlm.nih.gov/gene/423166", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR040028", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040028", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:423166", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423166", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KFINCHE", "url": "https://omabrowser.org/oma/group/KFINCHE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A6Q0", "url": "https://www.orthodb.org/?gene=A0A8V1A6Q0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR35543", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR35543", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR35543:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR35543:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF17722", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17722", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001273177", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001273177", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1A6Q0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6Q0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A6Q0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6Q0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGEQLVNNCILDQFINSHEQSYEEFLSTFTYLLKEDERKTIQGRKKSLRKSFSASEISNGNKQDGLPERSKEKLVSFPPQTPNENKTVINESWKSGGSDGNGLSLSERAQVDHHLETDIDGEPRNAGSFVLPGEVEEIGTSCTPPLEKPVQRKLKTSSVQQPLDNKAEELLGDDVQPFLLDEEFDYDNVALTPKFSEAELMPMKELSEEKKRGQM", "length": 215, "header": "tr|A0A8V1A6Q0-1|A0A8V1A6Q0_CHICK Isoform 1 of C11orf74 homolog OS=Gallus gallus OX=9031 GN=C11orf74 PE=4 SV=1 CANONICAL=A0A8V1A6Q0-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A6Q0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6Q0/entry#A0A8V1A6Q0-1", "sequence": { "sequence": "MGEQLVNNCILDQFINSHEQSYEEFLSTFTYLLKEDERKTIQGRKKSLRKSFSASEISNGNKQDGLPERSKEKLVSFPPQTPNENKTVINESWKSGGSDGNGLSLSERAQVDHHLETDIDGEPRNAGSFVLPGEVEEIGTSCTPPLEKPVQRKLKTSSVQQPLDNKAEELLGDDVQPFLLDEEFDYDNVALTPKFSEAELMPMKELSEEKKRGQM", "length": 215, "header": "tr|A0A8V1A6Q0-1|A0A8V1A6Q0_CHICK Isoform 1 of C11orf74 homolog OS=Gallus gallus OX=9031 GN=C11orf74 PE=4 SV=1 CANONICAL=A0A8V1A6Q0-1" }, "locus": { "chromosome": "5", "start_pos": 19096345, "end_pos": 19067226, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010061614.1", "url": "https://www.ensembl.org/id/ENSGALT00010061614.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038055.1", "url": "https://www.ensembl.org/id/ENSGALP00010038055.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:423166", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423166", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2MQQ5-1", "protein_name": "Intraflagellar transport-associated protein", "gene_name": "Iftap", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MPAQILRPEIMDEDQLMKEVLDKFINCHEQTYEEFLSTFTHLSKEDIVAKGGSHGSDSSENIFTAEKLIRKNESNGHHFRNTAIFPHTSSECSEEDQIVIDEGQQVGSFLQGDMTRAGKVKVDNFLDLEDLDMEEDSKPQMNKDWMLLPGEVEQGIITSVPAYVPSVDLPLSSEVKPKPAEGRTLKPTEEIFGDEVQPFFLDEEFDYDNVTLTPKFTAGEIATIQELAKQKRMDTNRDFFEAHN", "length": 244 }, "evidence": [ { "id": "A0A8V1A6Q0", "url": "https://omabrowser.org/oma/group/A0A8V1A6Q0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0ABK0LAT9-1", "protein_name": "Intraflagellar transport associated protein", "gene_name": "Iftap", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPAQIPRRPEIMSEDQLMKEVLDKFVNCHEQTYEEFLSTFTHLSKEDNVAKGGAHGMNLSENTLTAEKWNHKIESNGHHFRNRTIFLHDSSECSEEDQIVIDEGQKVGSSFQGDMTRAGKVKVDNFLDLEDVDTEEESKPQMNKDWMALPGEVEQGISISAPAYVPAVGLPLTSEGKPTPAVGRTQTQTEEILGDEVQPFFLDEDFDYDNVTLTPKFTAGEIATIQELAKQKRVDTSTHVCELHD", "length": 245 }, "evidence": [ { "id": "A0A8V1A6Q0", "url": "https://omabrowser.org/oma/group/A0A8V1A6Q0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q3ZBP0-1", "protein_name": "Intraflagellar transport-associated protein", "gene_name": "IFTAP", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPAKTPELEMMDEDRLIEEVLDKFVNCHEQTYEEFLRTFTHLSKDNVTKREAFGTNSSENNFTSIKFTQRNEPNDCRLSNKAIFLHTSSQCSEEEQIMIGDGQKAGSSFQGDLNRAGKVKVDNFLDIEDLDLDEEINPQLSKDVLLLPGQVEQEVSLSVPSYIPSVAIQPVTPGTKPRPTVKAADKQSKEIVGDEVQPFSLDEEFDYDAVVLTPKFTPAEMNAIKELSKQKTKSADLEDPHD", "length": 242 }, "evidence": [ { "id": "A0A8V1A6Q0", "url": "https://omabrowser.org/oma/group/A0A8V1A6Q0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q86VG3-1", "protein_name": "Intraflagellar transport-associated protein", "gene_name": "IFTAP", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSAHMSGLEIMDEDQLIKDVLDKFLNCHEQTYDEEFLNTFTHLSQEDHVSKRGVFGTDSSENIFTSAKVTHKNEADDYHLRNKTIFLRTSSQCLEEQVDNFLDLEDLDMDEEIKPQMSEDLLLLPGEVEQDVSTSIPSCIPFVAQPPTCEVKPKPSVKRMDKQTEEILGDEVQLFSLDEEFDYDNVMLTSKFSPAEIENIKELCKQQKRKDTSPDLEKSCD", "length": 221 }, "evidence": [ { "id": "A0A8V1A6Q0", "url": "https://omabrowser.org/oma/group/A0A8V1A6Q0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9CQI4-1", "protein_name": "Intraflagellar transport-associated protein", "gene_name": "Iftap", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLAQIPRPEIMDEDQLMKEVLDKFVNCHEQTYEEFLSTFTHLSKEDNVAKWGAHGTDSSENIFSTVKWNHKTESNGRHFRNTSIFLHTSSEHSEEDQIVIDEGHKVGSSFQGDMTRAGKVKVDNFLDLEDVDMEEESKPQMNKDCLLLPGEVEQDISTSVPSYDPSVDLPLTSEVRPKPAVGRTQKQTEEILGDEVQPFFLDEEFDYDNVTLTPKFTAGEIATIQELSKQKRVGSGTNVCELHD", "length": 244 }, "evidence": [ { "id": "A0A8V1A6Q0", "url": "https://omabrowser.org/oma/group/A0A8V1A6Q0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A6Q0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6Q0" } ], "pmid": "" }, { "name": "9+0 non-motile cilium", "id": "GO:0097731", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097731", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A6Q0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6Q0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "spermatogenesis", "id": "GO:0007283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007283", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A6Q0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6Q0" } ], "pmid": "" }, { "name": "acrosome reaction", "id": "GO:0007340", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007340", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A6Q0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6Q0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "intraciliary transport particle A binding", "id": "GO:0120160", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120160", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A6Q0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6Q0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 85, "end_pos": 87, "annotation": "n_glycosylation_sequon" }, { "start_pos": 90, "end_pos": 92, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 85, "end_pos": 87 }, { "start_pos": 90, "end_pos": 92 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": 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"uniprot_ac": "A0A8V1A5A1", "uniprot_id": "A0A8V1A5A1_CHICK", "mass": { "chemical_mass": 65728.0, "monoisotopic_mass": 65728.0 }, "refseq": { "ac": "XP_004945542", "name": "cell division control protein 45 homolog isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004945542" }, "gene_names": [ { "name": "CDC45", "type": "recommended", "evidence": [ { "id": "A0A8V1A5A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5A1" } ] }, { "name": "CDC45", "type": "synonym", "evidence": [ { "id": "XP_004945542", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004945542" } ] } ], "protein_names": [ { "name": "Cell division cycle 45", "type": "synonym", "evidence": [ { "id": "A0A8V1A5A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5A1/entry#names_and_taxonomy" } ] }, { "name": "cell division control protein 45 homolog isoform X1", "type": "synonym", "evidence": [ { "id": "XP_004945542", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004945542" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052546.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004945542.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004945542", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004945542" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A5A1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5A1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CDC45", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5A1", "locus": { "chromosome": "15", "start_pos": 706013, "end_pos": 693303, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010024480", "url": "https://www.ensembl.org/id/ENSGALG00010024480" } ] } } ], "crossref": [ { "id": "A0A8V1A5A1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A5A1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000001616", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000001616", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "416776", "url": "https://www.ncbi.nlm.nih.gov/gene/416776", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003874", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003874", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416776", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416776", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "EDCFMEA", "url": "https://omabrowser.org/oma/group/EDCFMEA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2UBE9", "url": "https://www.orthodb.org/?gene=A0A3Q2UBE9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZSM4", "url": "https://www.orthodb.org/?gene=A0A8V0ZSM4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZZY6", "url": "https://www.orthodb.org/?gene=A0A8V0ZZY6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A1V3", "url": "https://www.orthodb.org/?gene=A0A8V1A1V3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A5A1", "url": "https://www.orthodb.org/?gene=A0A8V1A5A1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10507", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10507", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10507:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10507:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02724", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02724", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-176187", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-176187", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-68962", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-68962", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_004945542", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004945542", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q2UBE9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UBE9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2UBE9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UBE9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZSM4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSM4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZSM4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSM4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZZY6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZY6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZZY6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZY6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A1V3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1V3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A1V3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1V3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A5A1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5A1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A5A1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5A1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFVTDCRREFYDVIVSQRVLLLVASDVDALCACKILQALFQCDHVQYTLVPVSGWQELETAFLEHKDQFKYFVFINCGANVDLLEILQPEEDTYFFVCDSHRPINVVNVYNETQVKLLVKQDDDLDVPAYDDIFRDEEDEEEDSENESDGSEPSDKRRRFEEEVIERTMRRRQRREWEARRREILFDYEQYEYHGTSSAMVMFDLAWIMSKDLNDMLWWAIVGLTDQWVQDKITHMKYVTDIGILQRHVSRHNHRNEDEENSLSIDCMRIAFEYDLRLALYQHWSLYESLCNTSYTSATLKLWSVQGQKRLQEFLADMGLPLKQVKQKFNSMDVSLKENLREMIEESANKFGMKDLRVQTFSIHFGFKNKFLASDIVYATASLMENIEKEGPETTNFIKALDSLSRGNLDKLHQGLDLAKKQLRAIQQTVASCICTNLVISQGPFLYCSLMEGTPDVKLFSKPVSLCLLSKYLLKSFVCSTKNKRCKLLPLIMAAPMDVEQGTVIMVGIPPETESSDKKNFFGRAFEKAADSTNSRTLHNHFDMSIIELKTEDRSKFLDALISLLS", "length": 566, "header": "tr|A0A8V1A5A1-1|A0A8V1A5A1_CHICK Isoform 1 of Cell division cycle 45 OS=Gallus gallus OX=9031 GN=CDC45 PE=3 SV=1 CANONICAL=A0A8V1A5A1-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2UBE9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5A1/entry#A0A3Q2UBE9-1", "sequence": { "sequence": "MFVTDCRREFYDVIVSQRVLLLVASDVDALCACKILQALFQCDHVQYTLVPVSGWQELETAFLEHKDQFKYFVFINCGANVDLLEILQPEEDTYFFVCDSHRPINVVNVYNETQVKLLVKQDDDLDVPAYDDIFRDEEDEEEDSENESDGSEPSDKRRRFEEEVIERTMRRRQRREWEARRREILFDYEQYEYHGTSSAMVMFDLAWIMSKDLNDMLWWAIVGLTDQWVQDKITHLRLALYQHWSLYESLCNTSYTSATLKLWSVQGQKRLQEFLADMGLPLKQVKQKFNSMDVSLKENLREMIEESANKFGMKDLRVQTFSIHFGFKNKFLASDIVYATASLMENIEKEGPETTNFIKALDSLSRGNLDKLHQGLDLAKKQLRAIQQTVASCICTNLVISQGPFLYCSLMEGTPDVKLFSKPVSLCLLSKYLLKSFVCSTKNKRCKLLPLIMAAPMDVEQGTVIMVGIPPETESSDKKNFFGRAFEKAADSTNSRTLHNHFDMSIIELKTEDRSKFLDALISLLS", "length": 526, "header": "tr|A0A3Q2UBE9-1|A0A3Q2UBE9_CHICK Computationally mapped isoform of Cell division cycle 45 OS=Gallus gallus OX=9031 GN=CDC45 PE=3 SV=1 CANONICAL=A0A8V1A5A1-1" }, "locus": { "chromosome": "15", "start_pos": 703774, "end_pos": 693675, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010059734.1", "url": "https://www.ensembl.org/id/ENSGALT00010059734.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036494.1", "url": "https://www.ensembl.org/id/ENSGALP00010036494.1" } ] } }, { "isoform_ac": "A0A8V0ZSM4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5A1/entry#A0A8V0ZSM4-1", "sequence": { "sequence": "MFVTDCRREFYDVIVSQRVLLLVASDVDALCACKILQALFQCDHVQYTLVPVSGWQELETAFLEHKDQFKYFVFINCGANVDLLEILQPEEDTYFFVCDSHRPINVVNVYNETQVKLLVKQDDDLDVPAYDDIFRDEEDEEEDSENESDGSEPSDKRRRFEEEVIERTMRRRQRREWEARRREILFDYEQYEYHGTSSAMVMFDLAWIMSKDLNDMLWWAIVGLTDQWVQDKITHMKYVTDIGILQRHVSRHNHRNEDEENSLSIDCMRIAFEYDLRLALYQHWSLYESLCNTSYTSATLKLWSVQGQKRLQEFLADMGLPLKQVKQKFNSMDVSLKENLREMIEESANKFGMKDLRVQTFSIHFGFKNKFLASDIVYATASLMENIEKEGPETTNFIKALDSLSRGNLDKLHQGLDLAKKQLRAIQQTVASCICTNLVISQGPFLYCSLMEGTPDVKLFSKPVSLCLLSKYLLKSFVCSTKNKRCKLLPLIMAAPMDVEQGTVIMVGIPPETESSDKKNFFGRAFEKAADSTNSRTLHNHFDMSMVLFGSLCWKLRIRCSEVVSDVPDFIVLQLCQLALFEMFQYRPGLWVLCLRG", "length": 597, "header": "tr|A0A8V0ZSM4-1|A0A8V0ZSM4_CHICK Computationally mapped isoform of Cell division cycle 45 OS=Gallus gallus OX=9031 GN=CDC45 PE=3 SV=1 CANONICAL=A0A8V1A5A1-1" }, "locus": { "chromosome": "15", "start_pos": 705149, "end_pos": 693675, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010059727.1", "url": "https://www.ensembl.org/id/ENSGALT00010059727.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036489.1", "url": "https://www.ensembl.org/id/ENSGALP00010036489.1" } ] } }, { "isoform_ac": "A0A8V0ZZY6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5A1/entry#A0A8V0ZZY6-1", "sequence": { "sequence": "MFVTDCRREFYDVIVSQRVLLLVASDVDALCACKILQALFQCDHVQYTLVPVSGWQELETAFLEHKDQVKLLVKQDDDLDVPAYDDIFRDEEDEEEDSENESDGSEPSDKRRRFEEEVIERTMRRRQRREWEARRREILFDYEQYEYHGTSSAMVMFDLAWIMSKDLNDMLWWAIVGLTDQWVQDKITHMKYVTDIGILQRHVSRHNHRNEDEENSLSIDCMRIAFEYDLRLALYQHWSLYESLCNTSYTSATLKLWSVQGQKRLQEFLADMGLPLKQVKQKFNSMDVSLKENLREMIEESANKFGMKDLRVQTFSIHFGFKNKFLASDIVYATASLMENIEKEGPETTNFIKALDSLSRGNLDKLHQGLDLAKKQLRAIQQTVASCICTNLVISQGPFLYCSLMEGTPDVKLFSKPVSLCLLSKYLLKSFVCSTKNKRCKLLPLIMAAPMDVEQGTVIMVGIPPETESSDKKNFFGRAFEKAADSTNSRTLHNHFDMSIIELKTEDRSKFLDALISLLS", "length": 520, "header": "tr|A0A8V0ZZY6-1|A0A8V1A5A1_CHICK Computationally mapped isoform of Cell division cycle 45 OS=Gallus gallus OX=9031 GN=CDC45 PE=3 SV=1 CANONICAL=A0A8V1A5A1-1" }, "locus": { "chromosome": "15", "start_pos": 703774, "end_pos": 693675, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010059719.1", "url": "https://www.ensembl.org/id/ENSGALT00010059719.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036483.1", "url": "https://www.ensembl.org/id/ENSGALP00010036483.1" } ] } }, { "isoform_ac": "A0A8V1A1V3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5A1/entry#A0A8V1A1V3-1", "sequence": { "sequence": "MFVTDCRREFYDVIVSQRVLLLVASDVDALCACKILQALFQCDHVQYTLVPVSGWQELETAFLEHKDQFKYFVFINCGANVDLLEILQPEEDTYFFVCDSHRPINVVNVYNETQVKLLVKQDDDLDVPAYDDIFRDEEDEEEDSENESDGSEPSDKRRRFEEEVIERTMRRRQRREWEARRREILFDYEQYEYHGTSSAMVMFDLAWIMSKDLNDMLWWAIVGLTDQWVQDKITHMKYVTDIGILQRHVSRHNHRNEDEENSLSIDCMRIAFEYDLRLALYQHWSLYESLCNTSYTSATLKLWSVQGQKRLQEFLADMGLPLKQVKQKFNSMDVSLKENLREMIEESANKFGGNLDKLHQGLDLAKKQLRAIQQTVASCICTNLVISQGPFLYCSLMEGTPDVKLFSKPVSLCLLSKYLLKSFVCSTKNKRCKLLPLIMAAPMDVEQGTVIMVGIPPETESSDKKNFFGRAFEKAADSTNSRTLHNHFDMSIIELKTEDRSKFLDALISLLS", "length": 512, "header": "tr|A0A8V1A1V3-1|A0A8V1A5A1_CHICK Computationally mapped isoform of Cell division cycle 45 OS=Gallus gallus OX=9031 GN=CDC45 PE=3 SV=1 CANONICAL=A0A8V1A5A1-1" }, "locus": { "chromosome": "15", "start_pos": 703774, "end_pos": 693675, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010059725.1", "url": "https://www.ensembl.org/id/ENSGALT00010059725.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036487.1", "url": "https://www.ensembl.org/id/ENSGALP00010036487.1" } ] } }, { "isoform_ac": "A0A8V1A5A1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5A1/entry#A0A8V1A5A1-1", "sequence": { "sequence": "MFVTDCRREFYDVIVSQRVLLLVASDVDALCACKILQALFQCDHVQYTLVPVSGWQELETAFLEHKDQFKYFVFINCGANVDLLEILQPEEDTYFFVCDSHRPINVVNVYNETQVKLLVKQDDDLDVPAYDDIFRDEEDEEEDSENESDGSEPSDKRRRFEEEVIERTMRRRQRREWEARRREILFDYEQYEYHGTSSAMVMFDLAWIMSKDLNDMLWWAIVGLTDQWVQDKITHMKYVTDIGILQRHVSRHNHRNEDEENSLSIDCMRIAFEYDLRLALYQHWSLYESLCNTSYTSATLKLWSVQGQKRLQEFLADMGLPLKQVKQKFNSMDVSLKENLREMIEESANKFGMKDLRVQTFSIHFGFKNKFLASDIVYATASLMENIEKEGPETTNFIKALDSLSRGNLDKLHQGLDLAKKQLRAIQQTVASCICTNLVISQGPFLYCSLMEGTPDVKLFSKPVSLCLLSKYLLKSFVCSTKNKRCKLLPLIMAAPMDVEQGTVIMVGIPPETESSDKKNFFGRAFEKAADSTNSRTLHNHFDMSIIELKTEDRSKFLDALISLLS", "length": 566, "header": "tr|A0A8V1A5A1-1|A0A8V1A5A1_CHICK Isoform 1 of Cell division cycle 45 OS=Gallus gallus OX=9031 GN=CDC45 PE=3 SV=1 CANONICAL=A0A8V1A5A1-1" }, "locus": { "chromosome": "15", "start_pos": 703774, "end_pos": 693675, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010059715.1", "url": "https://www.ensembl.org/id/ENSGALT00010059715.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036480.1", "url": "https://www.ensembl.org/id/ENSGALP00010036480.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:416776", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416776", "resource": "KEGG Pathway" }, { "id": "R-GGA-176187", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-176187", "resource": "Reactome", "description": "Activation of ATR in response to replication stress" }, { "id": "R-GGA-68962", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-68962", "resource": "Reactome", "description": "Activation of the pre-replicative complex" } ], "orthologs": [ { "uniprot_canonical_ac": "B1WBZ4-1", "protein_name": "Cell division cycle 45", "gene_name": "Cdc45", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFVTDFRKEFYELVHNQRVLLFVASDVDALCACKILQALFQCDHVQYTLVPVSGWQELETAFLEHKEQFSYFILINCGANVDLLDILQPDEDSIFFVCDTHRPVNVVNVYNDTQIKLLIKQEDDLEVPAYDDIFRDEAEDEEDLSENDDGGAEPSEKRLRLEGLEEEIVERNRKRRQRREWEARRKDILFDYEQYEYYGTSSAMVMFDLAWMMSKDLNDMLWWAIVGLTDQWLHDKITQMKYVTDVGVLQRHVSRHNHRNEAEENMLSVDCTRISFEYDLCLVLYQHWSLHESLYNTSYTAARFKLWSVHGQKRLQEFLADMGMKDIRVQTFSIQFGFRHKFLASDVVFATMSLMERPEKDGSGTDHFIQALDSLSRSNLDKLYLGLELAKKHLQATQQTIASCLCTNLVTSQGPFLYCSLMEGTPDVALFSKPASLSLLSRHLLKSFVCSTKNRRCKLLPLVMAAPLSMEQGTVTVVGIPPETDSSDRKNFFGRAFEKAAESTSSRTLHNYFDLSVIELKAEDRSKFLDALVSLLS", "length": 537 }, "evidence": [ { "id": "A0A8V1A5A1", "url": "https://omabrowser.org/oma/group/A0A8V1A5A1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O75419-1", "protein_name": "Cell division control protein 45 homolog", "gene_name": "CDC45", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MFVSDFRKEFYEVVQSQRVLLFVASDVDALCACKILQALFQCDHVQYTLVPVSGWQELETAFLEHKEQFHYFILINCGANVDLLDILQPDEDTIFFVCDTHRPVNVVNVYNDTQIKLLIKQDDDLEVPAYEDIFRDEEEDEEHSGNDSDGSEPSEKRTRLEEEIVEQTMRRRQRREWEARRRDILFDYEQYEYHGTSSAMVMFELAWMLSKDLNDMLWWAIVGLTDQWVQDKITQMKYVTDVGVLQRHVSRHNHRNEDEENTLSVDCTRISFEYDLRLVLYQHWSLHDSLCNTSYTAARFKLWSVHGQKRLQEFLADMGLPLKQVKQKFQAMDISLKENLREMIEESANKFGMKDMRVQTFSIHFGFKHKFLASDVVFATMSLMESPEKDGSGTDHFIQALDSLSRSNLDKLYHGLELAKKQLRATQQTIASCLCTNLVISQGPFLYCSLMEGTPDVMLFSRPASLSLLSKHLLKSFVCSTKNRRCKLLPLVMAAPLSMEHGTVTVVGIPPETDSSDRKNFFGRAFEKAAESTSSRMLHNHFDLSVIELKAEDRSKFLDALISLLS", "length": 566 }, "evidence": [ { "id": "A0A8V1A5A1", "url": "https://omabrowser.org/oma/group/A0A8V1A5A1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "O96989-1", "protein_name": "Cell division cycle 45", "gene_name": "Cdc45", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MFVQDLRNDFYRQLVGKRILIVVNYDIDAICASRILQALFKYDHMLYTVVPIMGVTGLKRAYGEHQGDVKYVVLVNCGGCVDIVELLQPSDDVTFFICDSHRPLDVCNIYSDRQVCILGDASLEENIPAFETIFYDSEGEDEDEDESSDTEQQHDDSGAGESDQEDQAPRSRKLSRLERHEQRILKQRARRQWESERDRIMFEYTQFSYYGRSAALMVFELAWKLSKDNMDLLWWAIVGITEQLLLGKIESGAYTLELEQIQSHVSRLTNKTNDQNTMSASKITFENDLHLVLYRHWPVTESMRYSRYSSCQLKLWTLRGEKRLHELLLEMGLPLVHARQTYGAMDLVLRKEFFSMVERLAEKYDIADIVYGTFTLSYGYRSRYAAADYVYALLAIMESVKKHKTPEDCFLEASDALSRQHKQLLSAGIDQAKLLHAAVFRQVQSSLEARQVHSAGSFFYYVLQEEHAFFSYPYALGLLARFLLRGHVATSRARQASDLPLIASCPLNASEGMCLLVGIVPVREDSPRNFFGKAFEQAAQKSGVALLQDFFEPAVVQLRQSDLTRFLDSLTVLLA", "length": 575 }, "evidence": [ { "id": "A0A8V1A5A1", "url": "https://omabrowser.org/oma/group/A0A8V1A5A1/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q08032-1", "protein_name": "Cell division control protein 45", "gene_name": "CDC45", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MYYGISQFSEAYNKILRNSSSHSSCQLVIFVSCLNIDALCATKMLSLLFKKQLVQSQIVPIFGYSELRRHYSQLDDNINSLLLVGFGGVIDLEAFLEIDPQEYVIDTDEKSGEQSFRRDIYVLDAHRPWNLDNIFGSQIIQCFDDGTVDDTLGEQKEAYYKLLELDEESGDDELSGDENDNNGGDDEATDADEVTDEDEEDEDETISNKRGNSSIGPNDLSKRKQRKKQIHEYEGVLEEYYSQGTTVVNSISAQIYSLLSAIGETNLSNLWLNILGTTSLDIAYAQVYNRLYPLLQDEVKRLTPSSRNSVKTPDTLTLNIQPDYYLFLLRHSSLYDSFYYSNYVNAKLSLWNENGKKRLHKMFARMGIPLSTAQETWLYMDHSIKRELGIIFDKNLDRYGLQDIIRDGFVRTLGYRGSISASEFVEALTALLEVGNSTDKDSVKINNDNNDDTDGEEEEDNSAQKLTNLRKRWVSNFWLSWDALDDRKVELLNRGIQLAQDLQRAIFNTGVAILEKKLIKHLRIYRLCVLQDGPDLDLYRNPLTLLRLGNWLIECCAESEDKQLLPMVLASIDENTDTYLVAGLTPRYPRGLDTIHTKKPILNNFSMAFQQITAETDAKVRIDNFESSIIEIRREDLSPFLEKLTLSGLL", "length": 650 }, "evidence": [ { "id": "A0A8V1A5A1", "url": "https://omabrowser.org/oma/group/A0A8V1A5A1/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q55GA4-1", "protein_name": "Cell division control protein 45 homolog", "gene_name": "cdc45", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MVLTTDTKFSEIYDIIKGDSVQGESVLILVARDCDSIAACKILTEILKSDLIAYNIKAVSGYEDLENVNSTLLENEEIKSIIMINCGGNIDITNVFTNLNDQQVAYIIDSHRPYSINNITNESSVLIIDDGTYIEQDELQQLSDDSEEEEEELEEEEAEEDVVEDEAEEAEEAEEAEEAEEAEFDPENEDNPENDEDDGGSENIDENERKSKKKNKKDKKSKRKHRKKKKKKSEKLEKTYYGKSAAVSMYSLSTFLNKQNLDDLLWYAVLGLTDQFIHEKITLDSYEQQYKNFKELILNNYPTDGDDDQEERYRPGNDEDDYDENGDLKRHPSSMFLHGDKIIPSDDFRFMLYRHWNLYESLFNSRYVACKLRVWKAKGRFQLESLFAMMGIPLDQVKQKYNSMNVHYKKQLKQLLAINGPKFGLVNLYFNSFLKKYSNNSEISASDTVYAVTALMESDNLESDQSDQDIWEQNFWEAYDSISNKNIDLLKIGLKQSIQLQKEITRQVTSMIEKRSVILSGPFRYAFITESSDLKYFIHPLALTKLGLFMMDAFISMGKAKRPFLIGALNENKNSYLIVGISGSHSTDIQSNTFGEYFRKSAEYTDATFKYQSFDTSIVEVSKTDLHKFVEHLHGTMQTTQISK", "length": 644 }, "evidence": [ { "id": "A0A8V1A5A1", "url": "https://omabrowser.org/oma/group/A0A8V1A5A1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q7ZU79-1", "protein_name": "Cell division control protein 45 homolog", "gene_name": "cdc45", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MFVTDIRKEFYDVVVNQRVALLVSSDIDALCACKVLQALFHCDHVQYTLVPVTGWQDLGTAFLEHKEQYKYFVLINCGANVDLLETLQPEEDSVFFICDTHRPVDVVNVYNDSQIKLLIKQDDDLGVPSYDDIFRDDEEDEEADGDDSGNESDGSAEPSGKRRRFDEDALERRIERQRARREWEARRREILFDYEQYEFHGTSAALVMFELAWVMSKDTKDMLWWSIIGLTDQWVHDKIPHMKYVTDIATLQRHVSRHNHKNEDEENSLSIDCMRINFEYDLRLVLYQHWSLYESICNSCYTSCSFKLWSINGQKKLQEFLADMGLPLKQVRQKFNSMDMTIKENLREVIEESATKFGMKDIRVQTFGVHFGFKNRFLASDVVHAAAALLENVEKDETPTDNFIKALDCLSRSNLERLHLGIDLAKKKLKAIQQTVASCICTNLILSQGPFLYCHLLEGTPDVKLFSKPLSLTLLSKYLLKAFVCSTRNKRCKILPLIMAAPLDIEKGTVIVMGIPPESETSDKKNFFGRAFEKAAESTSSRTLHDHFDTSVIELKMEDRGKFLDALITLLS", "length": 572 }, "evidence": [ { "id": "A0A8V1A5A1", "url": "https://omabrowser.org/oma/group/A0A8V1A5A1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q9LSG6-1", "protein_name": "Cell division cycle 45", "gene_name": "CDC45", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MVRIKKVESFYAKLRESATSLSSQNPLLIFPSTSDVDSLCALKVITHILESDSIQYSCFPVSSFLEIHKYAGPAGLCSTSLESPPVTILLINWGCHRDLKLVLKLGPSARVFVVDSHRPIHLHNLSDYNEQVVVLHTDDDERQGDLAYDFDVLKLANESFQLRVEDAGEESDEEEEDEEEDEEDDDDDDGDRPSKRRKMGDGVKVFKKLKRDYYKMGTFHGKPSGCLLFELSHMLRKNTNELLWLACVSLTDQFVHERLTDERYQAAVMELEQHINSSGNIDKITSVTLKDGTKVRAPDCSRISYEEEPRLMLLREWTLFDSMLCSSYIATKLKTWSDNGIKKLKLLLARMGFALIECQQKFPYMSLEVKRKMKQEFDRFLPEYGLNDFYYRSFLRLHGYSSRVSAADVVYGITALLESFLGSGGSSASKQFGEAYDALSLNNLDKLRSGMQQAIKVQRAILRQGSAAITKSGCIRSGRKFRWVKIEDSMDAKYLGYPQALTKFCYFLMDALREKGARMKPMLCACASQQPGKILVVGVCGKPRLGAVRGNAFGNAFRKAAQESRADYFHELFESSWIVLDASAVNSFMIRLTEKL", "length": 596 }, "evidence": [ { "id": "A0A8V1A5A1", "url": "https://omabrowser.org/oma/group/A0A8V1A5A1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9Z1X9-1", "protein_name": "Cell division control protein 45 homolog", "gene_name": "Cdc45", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFVTDFRKEFYETVHNQRVLLFVASDVDALCACKILQALFQCDHVQYTLVPVSGWQELETAYLEHKEQFSYFILINCGANVDLLDILQPDEDSIFFVCDTHRPVNVVNVYNDTQIKLLIKQEDDLEVPAYDDIFRDEAEDEDLSDSDGDGSEPSEKRTRLEEEIVERNRKRRQRREWEARRKDILFDYEQYEYYGTSSAMVMFDLAWMMSKDLNDMLWWAIVGLTDQWVHDKITQMKYVTDVGILQRHVSRHNHRNEAEENMLSVDCTRISFEYDLCLVLYQHWSLHESLYNTSYTAARFKLWSVHGQKRLQEFLADMGLPLKQVKQKFQSMDVSLKGNLREMIEESANKFGMKDMRVQTFSIQFGFKHKFLASDVVFATMSLMESPEKDGSGTDHFIQALDSLSRSNLDKLYLGLELAKKHLQATQQTIASCLCTNLVTSQGPFLYCSLMEGTPDVTLFSKPASLSLLSRHLLKSFVYSTKNRRCKLLPLVMAAPLSVEQGTVTVVGIPPETDSSDRKNFFGRAFEKAAESTSSRTLHNYFDLSVIELKAEDRSKFLDALVSLLS", "length": 566 }, "evidence": [ { "id": "A0A8V1A5A1", "url": "https://omabrowser.org/oma/group/A0A8V1A5A1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "DNA replication origin binding", "id": "GO:0003688", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003688", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A5A1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5A1" } ], "pmid": "" }, { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A5A1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5A1" } ], "pmid": "" }, { "name": "single-stranded DNA binding", "id": "GO:0003697", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003697", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A5A1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5A1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "DNA replication preinitiation complex", "id": "GO:0031261", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031261", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A5A1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5A1" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A5A1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5A1" } ], "pmid": "" }, { "name": "ciliary basal body", "id": "GO:0036064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036064", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A5A1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5A1" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A5A1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5A1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "mitotic DNA replication preinitiation complex assembly", "id": "GO:1902977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902977", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A5A1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5A1" } ], "pmid": "" }, { "name": "DNA replication initiation", "id": "GO:0006270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A5A1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5A1" } ], "pmid": "" }, { "name": "double-strand break repair via break-induced replication", "id": "GO:0000727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000727", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A5A1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5A1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 111, "end_pos": 113, "annotation": "n_glycosylation_sequon" }, { "start_pos": 146, "end_pos": 148, "annotation": "n_glycosylation_sequon" }, { "start_pos": 292, "end_pos": 294, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 111, "end_pos": 113 }, { "start_pos": 146, "end_pos": 148 }, { "start_pos": 292, "end_pos": 294 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A9J5-1", "uniprot_ac": "A0A8V1A9J5", "uniprot_id": "A0A8V1A9J5_CHICK", "mass": { "chemical_mass": 110957.0, "monoisotopic_mass": 110957.0 }, "refseq": {}, "gene_names": [ { "name": "GLIS1", "type": "recommended", "evidence": [ { "id": "A0A8V1A9J5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9J5" } ] } ], "protein_names": [ { "name": "GLIS family zinc finger 1", "type": "synonym", "evidence": [ { "id": "A0A8V1A9J5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9J5/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9J5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9J5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "GLIS1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9J5", "locus": { "chromosome": "8", "start_pos": 24592021, "end_pos": 24765862, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010025250", "url": "https://www.ensembl.org/id/ENSGALG00010025250" } ] } } ], "crossref": [ { "id": "A0A8V1A9J5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A9J5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000010721", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000010721", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "424652", "url": "https://www.ncbi.nlm.nih.gov/gene/424652", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043359", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043359", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048420", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048420", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056436", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056436", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:424652", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424652", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ECPSDYK", "url": "https://omabrowser.org/oma/group/ECPSDYK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A9J1", "url": "https://www.orthodb.org/?gene=A0A8V1A9J1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A9J5", "url": "https://www.orthodb.org/?gene=A0A8V1A9J5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1ND41", "url": "https://www.orthodb.org/?gene=F1ND41", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45718", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45718", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45718:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45718:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21816", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21816", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23561", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23561", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1A9J1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9J1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A9J1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9J1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A9J5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9J5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A9J5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9J5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1ND41", "url": "https://www.uniprot.org/uniprotkb/F1ND41", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1ND41-1", "url": "https://www.uniprot.org/uniprotkb/F1ND41-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLRSYKCILRTLSSFARELSGEGERDCPGGFIGTAAPRTACPSTLPVPAAGCGHPEPAAGWCSSEQSRASRLSLRLFGMRPKLIQLVRLLPDLSWAVRSRSKCHRCSTAGLEGDAAHRTGAAGRAPRARGGAERLRGETDKCRRAPRKEPRGIRPGAAKAPSNPPMSFKVTGSDGSERPEPRRSPAEMSAPLLDFGPKRPSIFERVPALPRAQELRCGRGAKDCVQQQRLQSGRVNGGYSHCNLISEKKNMMDMEMTSSSVPVCRQGLFIHTGNPLMRDHPLSCERLLHVGQLNLTHSDIRSPRFQDSVDSAAPCLNGSHPAQHIKQECPGDYKALSEASTHRRITEGMELRASGSLHPEIDLMNNSFTNSLSSYLFNNEHSSSPSPLSLGTPQHSARLQASNLKKRCISVVPSSAEGIDIAAIIRTSQTSLVTCVNGLRTNSAGISSHPVEISHHSAQKSSRPQSCSQPGNPCSIPSPPACLVPISTECDRGDCEQIQMQQVEENGSLSLMMNGTSIPHQNTSHSTQKVSFLKQEPADDYSSTTDLFRHHQGLPPPYHLHQQLSQTQGTLPHLHASMSPKSLQPSEGDEQDLGNGKQVCRWIDCSATYDQQDELVRHIEKTHIDQRKGEDFTCFWAGCVRRYKPFNARYKLLIHMRVHSGEKPNKCMFEGCNKAFSRLENLKIHLRSHTGEKPYLCQHPGCQKAFSNSSDRAKHQRTHLDTKPYACQIPGCSKRYTDPSSLRKHVKAHSAKEQQLNSCTDIEQDVLSECLAIQQLHTSSQHILDGKCGRSVGHHDLITGMYSGSSANHNGPSPGILPPPHDIPSRHHPLDSALSSPHHHQSPLESAREGLAPNIISPLVSPLKALVPPSLLQKHSSPSSHSQSPNGQQFPGIPNKPYAQFQNQSVQQGSQGYQGSFHSIQNCFHYGDCYRTMDQSVTSDVLTGESHCFNPLRHNGYHILSAPLASTGYDAISEAQCVSEDMVSNGTDENGFFQNGAFDHCLNHIPPIYTDT", "length": 1012, "header": "tr|A0A8V1A9J5-1|A0A8V1A9J5_CHICK Isoform 1 of GLIS family zinc finger 1 OS=Gallus gallus OX=9031 GN=GLIS1 PE=3 SV=1 CANONICAL=A0A8V1A9J5-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A9J1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9J5/entry#A0A8V1A9J1-1", "sequence": { "sequence": "MACCFYFWITCVLCASGFPVSRSVQAAFDAAKSCSVNGGYSHCNLISEKKNMMDMEMTSSSVPVCRQGLFIHTGNPLMRDHPLSCERLLHVGQLNLTHSDIRSPRFQDSVDSAAPCLNGSHPAQHIKQECPGDYKALSEASTHRRITEGMELRASGSLHPEIDLMNNSFTNSLSSYLFNNEHSSSPSPLSLGTPQHSARLQASNLKKRCISVVPSSAEGIDIAAIIRTSQTSLVTCVNGLRTNSAGISSHPVEISHHSAQKSSRPQSCSQPGNPCSIPSPPACLVPISTECDRGDCEQIQMQQVEENGSLSLMMNGTSIPHQNTSHSTQKVSFLKQEPADDYSSTTDLFRHHQGLPPPYHLHQQLSQTQGTLPHLHASMSPKSLQPSEGDEQDLGNGKQVCRWIDCSATYDQQDELVRHIEKTHIDQRKGEDFTCFWAGCVRRYKPFNARYKLLIHMRVHSGEKPNKCMFEGCNKAFSRLENLKIHLRSHTGEKPYLCQHPGCQKAFSNSSDRAKHQRTHLDTKPYACQIPGCSKRYTDPSSLRKHVKAHSAKEQQVRKKLNSCTDIEQDVLSECLAIQQLHTSSQHILDGKCGRSVGHHDLITGMYSGSSANHNGPSPGILPPPHDIPSRHHPLDSALSSPHHHQSPLESAREGLAPNIISPLVSPLKALVPPSLLQKHSSPSSHSQSPNGQQFPGIPNKPYAQFQNQSVQQGSQGYQGSFHSIQNCFHYGDCYRTMDQSVTSDVLTGESHCFNPLRHNGYHILSAPLASTGYDAISEAQCVSEDMVSNGTDENGFFQNGAFDHCLNHIPPIYTDT", "length": 817, "header": "tr|A0A8V1A9J1-1|A0A8V1A9J5_CHICK Computationally mapped isoform of GLIS family zinc finger 1 OS=Gallus gallus OX=9031 GN=GLIS1 PE=3 SV=1 CANONICAL=A0A8V1A9J5-1" }, "locus": { "chromosome": "8", "start_pos": 24747587, "end_pos": 24592526, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010061619.1", "url": "https://www.ensembl.org/id/ENSGALT00010061619.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038058.1", "url": "https://www.ensembl.org/id/ENSGALP00010038058.1" } ] } }, { "isoform_ac": "A0A8V1A9J5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9J5/entry#A0A8V1A9J5-1", "sequence": { "sequence": "MLRSYKCILRTLSSFARELSGEGERDCPGGFIGTAAPRTACPSTLPVPAAGCGHPEPAAGWCSSEQSRASRLSLRLFGMRPKLIQLVRLLPDLSWAVRSRSKCHRCSTAGLEGDAAHRTGAAGRAPRARGGAERLRGETDKCRRAPRKEPRGIRPGAAKAPSNPPMSFKVTGSDGSERPEPRRSPAEMSAPLLDFGPKRPSIFERVPALPRAQELRCGRGAKDCVQQQRLQSGRVNGGYSHCNLISEKKNMMDMEMTSSSVPVCRQGLFIHTGNPLMRDHPLSCERLLHVGQLNLTHSDIRSPRFQDSVDSAAPCLNGSHPAQHIKQECPGDYKALSEASTHRRITEGMELRASGSLHPEIDLMNNSFTNSLSSYLFNNEHSSSPSPLSLGTPQHSARLQASNLKKRCISVVPSSAEGIDIAAIIRTSQTSLVTCVNGLRTNSAGISSHPVEISHHSAQKSSRPQSCSQPGNPCSIPSPPACLVPISTECDRGDCEQIQMQQVEENGSLSLMMNGTSIPHQNTSHSTQKVSFLKQEPADDYSSTTDLFRHHQGLPPPYHLHQQLSQTQGTLPHLHASMSPKSLQPSEGDEQDLGNGKQVCRWIDCSATYDQQDELVRHIEKTHIDQRKGEDFTCFWAGCVRRYKPFNARYKLLIHMRVHSGEKPNKCMFEGCNKAFSRLENLKIHLRSHTGEKPYLCQHPGCQKAFSNSSDRAKHQRTHLDTKPYACQIPGCSKRYTDPSSLRKHVKAHSAKEQQLNSCTDIEQDVLSECLAIQQLHTSSQHILDGKCGRSVGHHDLITGMYSGSSANHNGPSPGILPPPHDIPSRHHPLDSALSSPHHHQSPLESAREGLAPNIISPLVSPLKALVPPSLLQKHSSPSSHSQSPNGQQFPGIPNKPYAQFQNQSVQQGSQGYQGSFHSIQNCFHYGDCYRTMDQSVTSDVLTGESHCFNPLRHNGYHILSAPLASTGYDAISEAQCVSEDMVSNGTDENGFFQNGAFDHCLNHIPPIYTDT", "length": 1012, "header": "tr|A0A8V1A9J5-1|A0A8V1A9J5_CHICK Isoform 1 of GLIS family zinc finger 1 OS=Gallus gallus OX=9031 GN=GLIS1 PE=3 SV=1 CANONICAL=A0A8V1A9J5-1" }, "locus": { "chromosome": "8", "start_pos": 24765684, "end_pos": 24592526, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010061625.1", "url": "https://www.ensembl.org/id/ENSGALT00010061625.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038063.1", "url": "https://www.ensembl.org/id/ENSGALP00010038063.1" } ] } }, { "isoform_ac": "F1ND41-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9J5/entry#F1ND41-1", "sequence": { "sequence": "MSFKVTGSDGSERPEPRRSPAEMSAPLLDFGPKRPSIFERVPALPRAQELRCGRGAKDCVQQQRLQSGRVNGGYSHCNLISEKKNMMDMEMTSSSVPVCRQGLFIHTGNPLMRDHPLSCERLLHVGQLNLTHSDIRSPRFQDSVDSAAPCLNGSHPAQHIKQECPGDYKALSEASTHRRITEGMELRASGSLHPEIDLMNNSFTNSLSSYLFNNEHSSSPSPLSLGTPQHSARLQASNLKKRCISVVPSSAEGIDIAAIIRTSQTSLVTCVNGLRTNSAGISSHPVEISHHSAQKSSRPQSCSQPGNPCSIPSPPACLVPISTECDRGDCEQIQMQQVEENGSLSLMMNGTSIPHQNTSHSTQKVSFLKQEPADDYSSTTDLFRHHQGLPPPYHLHQQLSQTQGTLPHLHASMSPKSLQPSEGDEQDLGNGKQVCRWIDCSATYDQQDELVRHIEKTHIDQRKGEDFTCFWAGCVRRYKPFNARYKLLIHMRVHSGEKPNKCMFEGCNKAFSRLENLKIHLRSHTGEKPYLCQHPGCQKAFSNSSDRAKHQRTHLDTKPYACQIPGCSKRYTDPSSLRKHVKAHSAKEQQVRKKLNSCTDIEQDVLSECLAIQQLHTSSQHILDGKCGRSVGHHDLITGMYSGSSANHNGPSPGILPPPHDIPSRHHPLDSALSSPHHHQSPLESAREGLAPNIISPLVSPLKALVPPSLLQKHSSPSSHSQSPNGQQFPGIPNKPYAQFQNQSVQQGSQGYQGSFHSIQNCFHYGDCYRTMDQSVTSDVLTGESHCFNPLRHNGYHILSAPLASTGYDAISEAQCVSEDMVSNGTDENGFFQNGAFDHCLNHIPPIYTDT", "length": 851, "header": "tr|F1ND41-1|A0A8V1A9J5_CHICK Computationally mapped isoform of GLIS family zinc finger 1 OS=Gallus gallus OX=9031 GN=GLIS1 PE=3 SV=3 CANONICAL=A0A8V1A9J5-1" }, "locus": { "chromosome": "8", "start_pos": 24764364, "end_pos": 24592526, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010061623.1", "url": "https://www.ensembl.org/id/ENSGALT00010061623.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038062.1", "url": "https://www.ensembl.org/id/ENSGALP00010038062.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:424652", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424652", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0ABK0LQ38-1", "protein_name": "GLIS family zinc finger 1", "gene_name": "Glis1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MYVSRVRFVGVRAHLQPGVWLVVWLAEILRLHPAAVRVHCLGSVQPSLGHLEEPGATPSRAPRPGAMHCEVAEALSDKRPKEAPGAPGPGRGPAGLEAHMAFRIAVSGGGCGDGNPRDLLPRLPVPPPRAHDLLRPRSPRDYSVSKAGGGKVNGSYGHSSEKSLLDLDLAEGPSPSCHQGLFLPAGTPPPRGHPPVCERLLHFPHPNRSPRPQATYANGSLPAAQHIKQEALPDYQAMVSAHTPLPTHCRAPLSMGLHSDLDFPGRGLTNPAPSCYLVGNEPISSLGPQPEAHLPEGSLKRCCLLGLPPTSSASSSPCASSDINPVIHSSQTALVSCVNGLRSPPLPGDLGGPPKRSRHGPGPGPVSSDGQEGSLQLEACRKSGFLKQEPMDEFSELFAPHQQGLPPPYPLPQLPTGPSLGGLGLGLAGRMAAGRQACRWVDCCAAYEQQEELVRHIEKSHIDQRKGEDFTCFWAGCVRRYKPFNARYKLLIHMRVHSGEKPNKCMFEGCSKAFSRLENLKIHLRSHTGEKPYLCQHPGCQKAFSNSSDRAKHQRTHLDTKPYACQIPGCSKRYTDPSSLRKHVKAHSAKEQQVRKKLHTGADPEAAVLSECLALQQLQASTPLPASRGKGSQTLSQELLPGVYPGSVTPQNGLASGILSPSHDVPSRHHPLEVTTGSHHHLSPLPTAESTRDGLGPGLLSPMVSPLKGLGPPPLPPASQSQSPGAQSFSTIPSKPTYPPFQSPPPPLPSPQGYQGSFHSIQNCFPYADCYRTTEPAASRDGLVGDAHGFNPLRPSTYSSLSTPLSAPGYEALAETPCPTLQPQPSEDLVSSGPEDCGFFPNGAFDHCLSHIPSIYTDT", "length": 859 }, "evidence": [ { "id": "A0A8V1A9J5", "url": "https://omabrowser.org/oma/group/A0A8V1A9J5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8K1M4-1", "protein_name": "Zinc finger protein GLIS1", "gene_name": "Glis1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MHCEVAEALSDKRPKEAPGAPGQGRGPVSLGAHMAFRIAVSGGGCGDGNPLDLLPRLPVPPPRAHDLLRPRSPRDYGVSKTGSGKVNGSYGHSSEKSLLDLDLAEGPSPSCHQGLFLPAGTPPPRGHPPVCEKLLHFPHPNRSPRPQATFVNGSLPAAQHIKQEALPDYQAMVSAHTPLPTHCRAPSSMGLPSDLDFPDRGLTNPAPSCYLLGNEPISDLGPQPEAHLPEGSLKRCCLLGLPPTSSASSSPCASSDINPVIHSSQTALVSCVNGLRSPPLPGDLGGPPKRSRPGPASSDGQEGSLQLEACRKSGFLKQEPMDEFSELFAPHHQGLPPPYPLPQLPTGPGLGGLGLGLAGRMVAGRQACRWVDCCAAYEQQEELVRHIEKSHIDQRKGEDFTCFWAGCVRRYKPFNARYKLLIHMRVHSGEKPNKCMFEGCSKAFSRLENLKIHLRSHTGEKPYLCQHPGCQKAFSNSSDRAKHQRTHLDTKPYACQIPGCSKRYTDPSSLRKHVKAHSAKEQQVRKKLHTGADPEADVLSECLSLQQLQASTLLPASRGKGSQTLSQELLPGVYPGSVTPQNGLASGILSPSHDVPSRHHPLEVPTGSHHHLSPLPTAESTRDGLGPSLLSPMVSPLKGLGPPPLPPASQSQSPGGQSFSTVPSKPTYPSFQSPPPLPSPQGYQGSFHSIQNCFPYADCYRATEPAASRDGLVGDAHGFNPLRPSTYSSLSTPLSAPGYETLAETPCPPALQPQPAEDLVPSGPEDCGFFPNGAFDHCLSHIPSIYTDT", "length": 789 }, "evidence": [ { "id": "A0A8V1A9J5", "url": "https://omabrowser.org/oma/group/A0A8V1A9J5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8NBF1-1", "protein_name": "Zinc finger protein GLIS1", "gene_name": "GLIS1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAEARTSLSAHCRGPLATGLHPDLDLPGRSLATPAPSCYLLGSEPSSGLGLQPETHLPEGSLKRCCVLGLPPTSPASSSPCASSDVTSIIRSSQTSLVTCVNGLRSPPLTGDLGGPSKRARPGPASTDSHEGSLQLEACRKASFLKQEPADEFSELFGPHQQGLPPPYPLSQLPPGPSLGGLGLGLAGRVVAGRQACRWVDCCAAYEQQEELVRHIEKSHIDQRKGEDFTCFWAGCVRRYKPFNARYKLLIHMRVHSGEKPNKCMFEGCSKAFSRLENLKIHLRSHTGEKPYLCQHPGCQKAFSNSSDRAKHQRTHLDTKPYACQIPGCSKRYTDPSSLRKHVKAHSAKEQQVRKKLHAGPDTEADVLTECLVLQQLHTSTQLAASDGKGGCGLGQELLPGVYPGSITPHNGLASGLLPPAHDVPSRHHPLDATTSSHHHLSPLPMAESTRDGLGPGLLSPIVSPLKGLGPPPLPPSSQSHSPGGQPFPTLPSKPSYPPFQSPPPPPLPSPQGYQGSFHSIQSCFPYGDCYRMAEPAAGGDGLVGETHGFNPLRPNGYHSLSTPLPATGYEALAEASCPTALPQQPSEDVVSSGPEDCGFFPNGAFDHCLGHIPSIYTDT", "length": 620 }, "evidence": [ { "id": "A0A8V1A9J5", "url": "https://omabrowser.org/oma/group/A0A8V1A9J5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9J5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9J5" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9J5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9J5" } ], "pmid": "" }, { "name": "nuclear body", "id": "GO:0016604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016604", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9J5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9J5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9J5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9J5" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9J5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9J5" } ], "pmid": "" }, { "name": "negative regulation of cell fate commitment", "id": "GO:0010454", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010454", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9J5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9J5" } ], "pmid": "" }, { "name": "fat cell differentiation", "id": "GO:0045444", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045444", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9J5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9J5" } ], "pmid": "" }, { "name": "osteoblast differentiation", "id": "GO:0001649", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001649", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9J5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9J5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9J5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9J5" } ], "pmid": "" }, { "name": "RNA polymerase II transcription regulatory region sequence-specific DNA binding", "id": "GO:0000977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000977", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9J5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9J5" } ], "pmid": "" }, { "name": "DNA-binding transcription repressor activity, RNA polymerase II-specific", "id": "GO:0001227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001227", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9J5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9J5" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9J5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9J5" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9J5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9J5" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9J5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9J5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 294, "end_pos": 296, "annotation": "n_glycosylation_sequon" }, { "start_pos": 317, "end_pos": 319, "annotation": "n_glycosylation_sequon" }, { "start_pos": 365, "end_pos": 367, "annotation": "n_glycosylation_sequon" }, { "start_pos": 506, "end_pos": 508, "annotation": "n_glycosylation_sequon" }, { "start_pos": 514, "end_pos": 516, "annotation": "n_glycosylation_sequon" }, { "start_pos": 522, "end_pos": 524, "annotation": "n_glycosylation_sequon" }, { "start_pos": 708, "end_pos": 710, "annotation": "n_glycosylation_sequon" }, { "start_pos": 903, "end_pos": 905, "annotation": "n_glycosylation_sequon" }, { "start_pos": 985, "end_pos": 987, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1A9J5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9J5" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 598, "end_pos": 628, "start_aa": "Gln", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 294, "end_pos": 296 }, { "start_pos": 317, "end_pos": 319 }, { "start_pos": 365, "end_pos": 367 }, { "start_pos": 506, "end_pos": 508 }, { "start_pos": 514, "end_pos": 516 }, { "start_pos": 522, "end_pos": 524 }, { "start_pos": 708, "end_pos": 710 }, { "start_pos": 903, "end_pos": 905 }, { "start_pos": 985, "end_pos": 987 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A720-1", "uniprot_ac": "A0A8V1A720", "uniprot_id": "A0A8V1A720_CHICK", "mass": { "chemical_mass": 25538.0, "monoisotopic_mass": 25538.0 }, "refseq": {}, "gene_names": [ { "name": "AP1S3", "type": "recommended", "evidence": [ { "id": "A0A8V1A720", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A720" } ] } ], "protein_names": [ { "name": "Adaptor related protein complex 1 sigma 3 subunit", "type": "synonym", "evidence": [ { "id": "A0A8V1A720", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A720/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A720", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A720" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "AP1S3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A720", "locus": { "chromosome": "9", "start_pos": 7934589, "end_pos": 7955387, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010025932", "url": "https://www.ensembl.org/id/ENSGALG00010025932" } ] } } ], "crossref": [ { "id": "A0A8V1A720", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A720", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000005171", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000005171", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd14831", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14831", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "424807", "url": "https://www.ncbi.nlm.nih.gov/gene/424807", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000804", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000804", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011012", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011012", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016635", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016635", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022775", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022775", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044733", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044733", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ETMAEYM", "url": "https://omabrowser.org/oma/group/ETMAEYM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A4P7", "url": "https://www.orthodb.org/?gene=A0A8V1A4P7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A4Q6", "url": "https://www.orthodb.org/?gene=A0A8V1A4Q6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A720", "url": "https://www.orthodb.org/?gene=A0A8V1A720", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A9S1", "url": "https://www.orthodb.org/?gene=A0A8V1A9S1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A9T8", "url": "https://www.orthodb.org/?gene=A0A8V1A9T8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AC37", "url": "https://www.orthodb.org/?gene=A0A8V1AC37", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BWN8", "url": "https://www.orthodb.org/?gene=E1BWN8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11753", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11753", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01217", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01217", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-432720", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-432720", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-432722", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-432722", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1A4P7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4P7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A4P7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4P7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A4Q6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Q6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A4Q6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Q6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A720", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A720", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A720-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A720-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A9S1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9S1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A9S1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9S1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A9T8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9T8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A9T8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9T8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AC37", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC37", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AC37-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC37-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BWN8", "url": "https://www.uniprot.org/uniprotkb/E1BWN8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BWN8-1", "url": "https://www.uniprot.org/uniprotkb/E1BWN8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "RRVWFHVGSSGWSPSSAVLRAARLHPPQELSEPRRCREPSVAEVVWSGSEIITVPIHFILLFSRQGKLRLQKWYTTLPEKEKKKIVREIVQIVLSRNQKTSSFVDWKDLKLVYKRYASLYFCCAIEDQDNELLTLEVVHRYVELLDRYFGNVWNILFFCQVCELDIIFNFEKAYFILDEFIIGGEVQDTSKRSAVKAMEDSDMLQETVEEYMNKPAF", "length": 217, "header": "tr|A0A8V1A720-1|A0A8V1A720_CHICK Isoform 1 of Adaptor related protein complex 1 sigma 3 subunit OS=Gallus gallus OX=9031 GN=AP1S3 PE=1 SV=1 CANONICAL=A0A8V1A720-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A4P7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A720/entry#A0A8V1A4P7-1", "sequence": { "sequence": "MPPNRWIHFILLFSRQGKLRLQKWYTTLPEKEKKKIVREIVQIVLSRNQKTSSFVDWKDLKLVYKRYASLYFCCAIEDQDNELLTLEVVHRYVELLDRYFGNVCELDIIFNFEKAYFILDEFIIGGEVQDTSKRSAVKAMEDSDMLQETVEEYMNKPAF", "length": 159, "header": "tr|A0A8V1A4P7-1|A0A8V1A720_CHICK Computationally mapped isoform of Adaptor related protein complex 1 sigma 3 subunit OS=Gallus gallus OX=9031 GN=AP1S3 PE=1 SV=1 CANONICAL=A0A8V1A720-1" }, "locus": { "chromosome": "9", "start_pos": 7948729, "end_pos": 7936707, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063216.1", "url": "https://www.ensembl.org/id/ENSGALT00010063216.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039020.1", "url": "https://www.ensembl.org/id/ENSGALP00010039020.1" } ] } }, { "isoform_ac": "A0A8V1A4Q6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A720/entry#A0A8V1A4Q6-1", "sequence": { "sequence": "VRASAASGPDLELPTETLSLWKSHVLSASATYQQIPASGYRDLLLSWQSCSHPALSSSSGSKRGLAKPSHVRYASLYFCCAIEDQDNELLTLEVVHRYVELLDRYFGNVWNILFFCQVCELDIIFNFEKAYFILDEFIIGGEVQDTSKRSAVKAMEDSDMLQETVEEYMNKPAF", "length": 174, "header": "tr|A0A8V1A4Q6-1|A0A8V1A720_CHICK Computationally mapped isoform of Adaptor related protein complex 1 sigma 3 subunit OS=Gallus gallus OX=9031 GN=AP1S3 PE=1 SV=1 CANONICAL=A0A8V1A720-1" }, "locus": { "chromosome": "9", "start_pos": 7952384, "end_pos": 7936707, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063228.1", "url": "https://www.ensembl.org/id/ENSGALT00010063228.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039031.1", "url": "https://www.ensembl.org/id/ENSGALP00010039031.1" } ] } }, { "isoform_ac": "A0A8V1A720-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A720/entry#A0A8V1A720-1", "sequence": { "sequence": "RRVWFHVGSSGWSPSSAVLRAARLHPPQELSEPRRCREPSVAEVVWSGSEIITVPIHFILLFSRQGKLRLQKWYTTLPEKEKKKIVREIVQIVLSRNQKTSSFVDWKDLKLVYKRYASLYFCCAIEDQDNELLTLEVVHRYVELLDRYFGNVWNILFFCQVCELDIIFNFEKAYFILDEFIIGGEVQDTSKRSAVKAMEDSDMLQETVEEYMNKPAF", "length": 217, "header": "tr|A0A8V1A720-1|A0A8V1A720_CHICK Isoform 1 of Adaptor related protein complex 1 sigma 3 subunit OS=Gallus gallus OX=9031 GN=AP1S3 PE=1 SV=1 CANONICAL=A0A8V1A720-1" }, "locus": { "chromosome": "9", "start_pos": 7951269, "end_pos": 7936707, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063218.1", "url": "https://www.ensembl.org/id/ENSGALT00010063218.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039022.1", "url": "https://www.ensembl.org/id/ENSGALP00010039022.1" } ] } }, { "isoform_ac": "A0A8V1A9S1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A720/entry#A0A8V1A9S1-1", "sequence": { "sequence": "ITAVRTVPLKIHFILLFSRQGKLRLQKWYTTLPEKEKKKIVREIVQIVLSRNQKTSSFVDWKDLKLVYKRYASLYFCCAIEDQDNELLTLEVVHRYVELLDRYFGNVCELDIIFNFEKAYFILDEFIIGGEVQDTSKRSAVKAMEDSDMLQETVEEYMNKPAF", "length": 163, "header": "tr|A0A8V1A9S1-1|A0A8V1A720_CHICK Computationally mapped isoform of Adaptor related protein complex 1 sigma 3 subunit OS=Gallus gallus OX=9031 GN=AP1S3 PE=1 SV=1 CANONICAL=A0A8V1A720-1" }, "locus": { "chromosome": "9", "start_pos": 7950503, "end_pos": 7936707, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063217.1", "url": "https://www.ensembl.org/id/ENSGALT00010063217.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039021.1", "url": "https://www.ensembl.org/id/ENSGALP00010039021.1" } ] } }, { "isoform_ac": "A0A8V1A9T8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A720/entry#A0A8V1A9T8-1", "sequence": { "sequence": "MGLWGAAAGIVYSIHFILLFSRQGKLRLQKWYTTLPEKEKKKIVREIVQIVLSRNQKTSSFVDWKDLKLVYKRYASLYFCCAIEDQDNELLTLEVVHRYVELLDRYFGNVCELDIIFNFEKAYFILDEFIIGGEVQDTSKRSAVKAMEDSDMLQETVEEYMNKPAF", "length": 166, "header": "tr|A0A8V1A9T8-1|A0A8V1A720_CHICK Computationally mapped isoform of Adaptor related protein complex 1 sigma 3 subunit OS=Gallus gallus OX=9031 GN=AP1S3 PE=1 SV=1 CANONICAL=A0A8V1A720-1" }, "locus": { "chromosome": "9", "start_pos": 7955233, "end_pos": 7936707, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063235.1", "url": "https://www.ensembl.org/id/ENSGALT00010063235.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039037.1", "url": "https://www.ensembl.org/id/ENSGALP00010039037.1" } ] } }, { "isoform_ac": "A0A8V1AC37-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A720/entry#A0A8V1AC37-1", "sequence": { "sequence": "NAESVEVACSFGICYLSANPCQRLQGFAAQLAELFASCSLIQLRLEARIHFILLFSRQGKLRLQKWYTTLPEKEKKKIVREIVQIVLSRNQKTSSFVDWKDLKLVYKRYASLYFCCAIEDQDNELLTLEVVHRYVELLDRYFGNVCELDIIFNFEKAYFILDEFIIGGEVQDTSKRSAVKAMEDSDMLQETVEEYMNKPAF", "length": 201, "header": "tr|A0A8V1AC37-1|A0A8V1AC37_CHICK Computationally mapped isoform of Adaptor related protein complex 1 sigma 3 subunit OS=Gallus gallus OX=9031 GN=AP1S3 PE=1 SV=1 CANONICAL=A0A8V1A720-1" }, "locus": { "chromosome": "9", "start_pos": 7952337, "end_pos": 7936707, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063221.1", "url": "https://www.ensembl.org/id/ENSGALT00010063221.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039024.1", "url": "https://www.ensembl.org/id/ENSGALP00010039024.1" } ] } }, { "isoform_ac": "E1BWN8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A720/entry#E1BWN8-1", "sequence": { "sequence": "MILITDLEAWLEVLVEIHFILLFSRQGKLRLQKWYTTLPEKEKKKIVREIVQIVLSRNQKTSSFVDWKDLKLVYKRYASLYFCCAIEDQDNELLTLEVVHRYVELLDRYFGNVCELDIIFNFEKAYFILDEFIIGGEVQDTSKRSAVKAMEDSDMLQETVEEYMNKPAF", "length": 169, "header": "tr|E1BWN8-1|A0A8V1A720_CHICK Computationally mapped isoform of Adaptor related protein complex 1 sigma 3 subunit OS=Gallus gallus OX=9031 GN=AP1S3 PE=1 SV=2 CANONICAL=A0A8V1A720-1" }, "locus": { "chromosome": "9", "start_pos": 7949314, "end_pos": 7936707, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063213.1", "url": "https://www.ensembl.org/id/ENSGALT00010063213.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039019.1", "url": "https://www.ensembl.org/id/ENSGALP00010039019.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-432720", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-432720", "resource": "Reactome", "description": "Lysosome Vesicle Biogenesis" }, { "id": "R-GGA-432722", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-432722", "resource": "Reactome", "description": "Golgi Associated Vesicle Biogenesis" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287A638-1", "protein_name": "AP complex subunit sigma", "gene_name": "AP1S3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MIHFILLFSRQGKLRLQKWYTTLPDKERKKITREIVQIILSRGQRTSSFIDWKELKLVYKRYASLYFCCAVENQDNELLTLEIVHRYVELLDKYFGNVCELDIIFNFEKAYFILDEFIMGGEIQETSKKSAVKAIEDSDMLQETMEEYMNKPAF", "length": 154 }, "evidence": [ { "id": "A0A8V1A720", "url": "https://omabrowser.org/oma/group/A0A8V1A720/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8C2QPL9-1", "protein_name": "AP complex subunit sigma", "gene_name": "Ap1s3", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MIHFILLFSRQGKLRLQKWYTTLPDKERKKITREIIQSVLSRGHRTSSFIDWKELKLVYKRYASLYFCCAIENQDNELLTLEIVHRYVELLDKYFGNVCELDIIFNFEKAYFILDEFIIGGEIQETSKKTAVKAIEDSDMLQETMEEYMNKPTF", "length": 154 }, "evidence": [ { "id": "A0A8V1A720", "url": "https://omabrowser.org/oma/group/A0A8V1A720/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0ABK0L464-1", "protein_name": "Adaptor related protein complex 1 subunit sigma 3", "gene_name": "Ap1s3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MATGNLEVAGFQISRTDTALQPLRLPLGSVQHLSFPSVLWLLFGRLITSPGGSLPGFRIHFILLFSRQGKLRLQKWYTTLPDKERKKITREIIQTVLSRGHRTSSFIDWKELKLVYKRYASLYFCCAIENQDNELLTLEIVHRYVELLDKYFGNVCELDIIFNFEKAYFILDEFIIGGEIQETSKKTAVKAIEDSDMLQETMEEYMNKPTF", "length": 211 }, "evidence": [ { "id": "A0A8V1A720", "url": "https://omabrowser.org/oma/group/A0A8V1A720/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7TN05-1", "protein_name": "AP-1 complex subunit sigma-3", "gene_name": "Ap1s3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIHFILLFSRQGKLRLQKWYTTLPDKERKKITRDIIQTVLSRGHRTSSFIDWKELKLVYKRYASLYFCCAIENQDNELLTLEIVHRYVELLDKYFGNVCELDIIFNFEKAYFILDEFIIGGEIQETSKKTAVKAIEDSDMLQETMEEYMNKPTF", "length": 154 }, "evidence": [ { "id": "A0A8V1A720", "url": "https://omabrowser.org/oma/group/A0A8V1A720/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96PC3-1", "protein_name": "AP-1 complex subunit sigma-3", "gene_name": "AP1S3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MIHFILLFSRQGKLRLQKWYITLPDKERKKITREIVQIILSRGHRTSSFVDWKELKLVYKRYASLYFCCAIENQDNELLTLEIVHRYVELLDKYFGNVCELDIIFNFEKAYFILDEFIIGGEIQETSKKIAVKAIEDSDMLQEVSTVSQTMGER", "length": 154 }, "evidence": [ { "id": "A0A8V1A720", "url": "https://omabrowser.org/oma/group/A0A8V1A720/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "clathrin-coated pit", "id": "GO:0005905", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005905", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A720", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A720" } ], "pmid": "" }, { "name": "AP-1 adaptor complex", "id": "GO:0030121", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030121", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A720", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A720" } ], "pmid": "" }, { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A720", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A720" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A720", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A720" } ], "pmid": "" }, { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A720", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A720" } ], "pmid": "" }, { "name": "protein targeting", "id": "GO:0006605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006605", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A720", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A720" } ], "pmid": "" }, { "name": "vesicle-mediated transport", "id": "GO:0016192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016192", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A720", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A720" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "clathrin adaptor activity", "id": "GO:0035615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035615", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A720", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A720" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1A720", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A720" }, { "id": "PF01217", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01217" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "AP complex mu/sigma subunit", "eco_id": "ECO_0000259", "start_pos": 56, "end_pos": 202, "start_aa": "Ile", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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"https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05890", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100857875", "url": "https://www.ncbi.nlm.nih.gov/gene/100857875", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013106", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013106", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013162", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013162", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041850", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041850", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051427", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051427", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A529", "url": "https://www.orthodb.org/?gene=A0A8V1A529", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AA54", "url": "https://www.orthodb.org/?gene=A0A8V1AA54", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AA59", "url": "https://www.orthodb.org/?gene=A0A8V1AA59", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ACF8", "url": "https://www.orthodb.org/?gene=A0A8V1ACF8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23277", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23277", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23277:SF69", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23277:SF69", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07686", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07686", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08205", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08205", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13927", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13927", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-418990", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-418990", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-420597", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-420597", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1A529", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A529", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A529-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A529-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AA54", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA54", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AA54-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA54-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AA59", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA59", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AA59-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA59-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ACF8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ACF8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASQLQTSCRASWWTIGVCILAAALFPGLQAQTVLVNDTVSGYIGTDVVLHCSFTNPLPNVKITQVTWQKVTNGTKQNVAIYNPAMGVSILPPYKERVTFRNPSFKDGTIQLSRLELEDEGVYICEFATFPTGNRESQLNLTVLAKPTNRMEGTTRPLIAKSGRTEKILVATCISSNGKPPSTVTWDTKLKGEAEFQEIRNSNGTFTVISRYRLVPSREAHRQQLMCVVNYQLDRFTDSITLNVQYEPEVTIEGFDGNWFLNRKDVKLICKSDANPPAHTYEWKLPNGTLPGSVEIQNNTIYFKGPVSYSVAGTYICEASNAIGTRSGLVEVNVTDKPLPQGALGGIIGIVGGVIAAALILGVAVTVFIVYRRQQKDRTEADHDLIDLPPSHKPAPPPKRKQELKSHLTAEDIQVVHLDNMTHEEELQKLPLQPPYYDMAASEPSAYTDKLNFGKCHSEIPNASDYLTRCYSHDDRYLQKIPHVYAPLSDLPQDLYPHHSDISFCCPPPGSRAPYICPKEQYV", "length": 523, "header": "tr|A0A8V1AA59-1|A0A8V1AA59_CHICK Isoform 1 of Nectin cell adhesion molecule 1 OS=Gallus gallus OX=9031 GN=NECTIN1 PE=3 SV=1 CANONICAL=A0A8V1AA59-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A529-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA59/entry#A0A8V1A529-1", "sequence": { "sequence": "MASQLQTSCRASWWTIGTDVVLHCSFTNPLPNVKITQVTWQKVTNGTKQNVAIYNPAMGVSILPPYKERVTFRNPSFKDGTIQLSRLELEDEGVYICEFATFPTGNRESQLNLTVLAKPTNRMEGTTRPLIAKSGRTEKILVATCISSNGKPPSTVTWDTKLKGEAEFQEIRNSNGTFTVISRYRLVPSREAHRQQLMCVVNYQLDRFTDSITLNVQYEPEVTIEGFDGNWFLNRKDVKLICKSDANPPAHTYEWKLPNGTLPGSVEIQNNTIYFKGPVSYSVAGTYICEASNAIGTRSGLVEVNVTEFPYTPSPIDDRKSMVQPNIPTPVIGGIVGGVSLVLVVAVVLFVVLRRRRHTFKGDYSTKKHVYGNGYSKAGIPQHHPPMAQNLQYPDDSDDEKKPGPLGGSTYEDEDEDAGGERKLGGPTKYEEDAKRPYFTVDEGEAHPEPYDERTLGFQYDPEQLDIAENMVSQNDGSFISKKEWYV", "length": 487, "header": "tr|A0A8V1A529-1|A0A8V1AA59_CHICK Computationally mapped isoform of Nectin cell adhesion molecule 1 OS=Gallus gallus OX=9031 GN=NECTIN1 PE=3 SV=1 CANONICAL=A0A8V1AA59-1" }, "locus": { "chromosome": "24", "start_pos": 4131312, "end_pos": 4087788, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063418.1", "url": "https://www.ensembl.org/id/ENSGALT00010063418.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039146.1", "url": "https://www.ensembl.org/id/ENSGALP00010039146.1" } ] } }, { "isoform_ac": "A0A8V1AA54-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA59/entry#A0A8V1AA54-1", "sequence": { "sequence": "MASQLQTSCRASWWTIGVCILAAALFPGLQAQTVLVNDTVSGYIGTDVVLHCSFTNPLPNVKITQVTWQKVTNGTKQNVAIYNPAMGVSILPPYKERVTFRNPSFKDGTIQLSRLELEDEGVYICEFATFPTGNRESQLNLTVLAKPTNRMEGTTRPLIAKSGRTEKILVATCISSNGKPPSTVTWDTKLKGEAEFQEIRNSNGTFTVISRYRLVPSREAHRQQLMCVVNYQLDRFTDSITLNVQYEPEVTIEGFDGNWFLNRKDVKLICKSDANPPAHTYEWKLPNGTLPGSVEIQNNTIYFKGPVSYSVAGTYICEASNAIGTRSGLVEVNVTEFPYTPSPIDDRKSMVQPNIPTPVIGGIVGGVSLVLVVAVVLFVVLRRRRHTFKGDYSTKKHVYGNGYSKAGIPQHHPPMAQNLQYPDDSDDEKKPGPLGGSTYEDEDEDAGGERKLGGPTKYEEDAKRPYFTVDEGEAHPEPYDERTLGFQYDPEQLDIAENMVSQNDGSFISKKE", "length": 512, "header": "tr|A0A8V1AA54-1|A0A8V1AA59_CHICK Computationally mapped isoform of Nectin cell adhesion molecule 1 OS=Gallus gallus OX=9031 GN=NECTIN1 PE=3 SV=1 CANONICAL=A0A8V1AA59-1" }, "locus": { "chromosome": "24", "start_pos": 4131305, "end_pos": 4087788, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063419.1", "url": "https://www.ensembl.org/id/ENSGALT00010063419.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039147.1", "url": "https://www.ensembl.org/id/ENSGALP00010039147.1" } ] } }, { "isoform_ac": "A0A8V1AA59-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA59/entry#A0A8V1AA59-1", "sequence": { "sequence": "MASQLQTSCRASWWTIGVCILAAALFPGLQAQTVLVNDTVSGYIGTDVVLHCSFTNPLPNVKITQVTWQKVTNGTKQNVAIYNPAMGVSILPPYKERVTFRNPSFKDGTIQLSRLELEDEGVYICEFATFPTGNRESQLNLTVLAKPTNRMEGTTRPLIAKSGRTEKILVATCISSNGKPPSTVTWDTKLKGEAEFQEIRNSNGTFTVISRYRLVPSREAHRQQLMCVVNYQLDRFTDSITLNVQYEPEVTIEGFDGNWFLNRKDVKLICKSDANPPAHTYEWKLPNGTLPGSVEIQNNTIYFKGPVSYSVAGTYICEASNAIGTRSGLVEVNVTDKPLPQGALGGIIGIVGGVIAAALILGVAVTVFIVYRRQQKDRTEADHDLIDLPPSHKPAPPPKRKQELKSHLTAEDIQVVHLDNMTHEEELQKLPLQPPYYDMAASEPSAYTDKLNFGKCHSEIPNASDYLTRCYSHDDRYLQKIPHVYAPLSDLPQDLYPHHSDISFCCPPPGSRAPYICPKEQYV", "length": 523, "header": "tr|A0A8V1AA59-1|A0A8V1AA59_CHICK Isoform 1 of Nectin cell adhesion molecule 1 OS=Gallus gallus OX=9031 GN=NECTIN1 PE=3 SV=1 CANONICAL=A0A8V1AA59-1" }, "locus": { "chromosome": "24", "start_pos": 4158011, "end_pos": 4087788, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063427.1", "url": "https://www.ensembl.org/id/ENSGALT00010063427.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039152.1", "url": "https://www.ensembl.org/id/ENSGALP00010039152.1" } ] } }, { "isoform_ac": "A0A8V1ACF8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA59/entry#A0A8V1ACF8-1", "sequence": { "sequence": "MASQLQTSCRASWWTIGVCILAAALFPGLQAQTVLVNDTVSGYIGTDVVLHCSFTNPLPNVKITQVTWQKVTNGTKQNVAIYNPAMGVSILPPYKERVTFRNPSFKDGTIQLSRLELEDEGVYICEFATFPTGNRESQLNLTVLAKPTNRMEGTTRPLIAKSGRTEKILVATCISSNGKPPSTVTWDTKLKGEAEFQEIRNSNGTFTVISRYRLVPSREAHRQQLMCVVNYQLDRFTDSITLNVQYEPEVTIEGFDGNWFLNRKDVKLICKSDANPPAHTYEWKLPNGTLPGSVEIQNNTIYFKGPVSYSVAGTYICEASNAIGTRSGLVEVNVTDKPLPQGALGGIIGIVGGVIAAALILGVAVTVFIVYRRQQKDRTEADHDLIDLPPSHKPAPPPKRKQELKSHLTAEDIQVVHLDNMTHEEELQKLPLQPPYYDMAASEPSAYTDKLNSGTKDCDVHYAELDTAALASSPSPRTSIHAGGDLVEYATIQPNLR", "length": 497, "header": "tr|A0A8V1ACF8-1|A0A8V1ACF8_CHICK Computationally mapped isoform of Nectin cell adhesion molecule 1 OS=Gallus gallus OX=9031 GN=NECTIN1 PE=3 SV=1 CANONICAL=A0A8V1AA59-1" }, "locus": { "chromosome": "24", "start_pos": 4152058, "end_pos": 4087788, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063424.1", "url": "https://www.ensembl.org/id/ENSGALT00010063424.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039150.1", "url": "https://www.ensembl.org/id/ENSGALP00010039150.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-418990", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-418990", "resource": "Reactome", "description": "Adherens junctions interactions" }, { "id": "R-GGA-420597", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-420597", "resource": "Reactome", "description": "Nectin/Necl trans heterodimerization" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AA59", 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This record is derived from a genomic sequence (NC_052533.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. 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"database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AEA8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEA8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AEA8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEA8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGA5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGA5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGA5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGA5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "R4GKH9", "url": "https://www.uniprot.org/uniprotkb/R4GKH9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "R4GKH9-1", "url": "https://www.uniprot.org/uniprotkb/R4GKH9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRATGAHVLERSAALRHGTERSELGGARCPRHAIRSAARPPAAARLPPIRGCRRQWDNITCWPEAQVGAVVVKPCPKYFRFLTTFLGNVSRNCTSQGWTDVYPAPYAVACGYDSNSTPGEEQTAFYGTVKTGYTIGHTLSLIALTAAMIILCLFRKLHCTRNYIHMHLFMSFIMRAIAVFIKDVILFESGEPEHCFVSSVGCKAMMVFFQYCVMANFFWLLVEGLYLHTLLVISFFSERKYFWWYILIGWGAPSVFITAWTVVRIYFFNVGCWEEIIETPIWWIIKTPILVSILVNFILFICIIRILVQKLHSPDVGHNETSQYSRLAKSTLLLIPLFGIHYIMFAFFPDNFKAEVKLVFELVVGSFQGFVVAVLYCFLNGEVQAELKRKWRRWHLERFLGSDMKYHHPSLGSNGTNFSTQISMLTKCSPKTRRCSSFQAEFSLV", "length": 445, "header": "tr|A0A8V1A8V6-1|A0A8V1A8V6_CHICK Isoform 1 of Vasoactive intestinal peptide receptor 1 OS=Gallus gallus OX=9031 GN=VIPR1 PE=3 SV=1 CANONICAL=A0A8V1A8V6-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A401-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8V6/entry#A0A8V1A401-1", "sequence": { "sequence": "MASSTRPECSIMLEIEEERSQCLAEITEDNQTSGCRRQWDNITCWPEAQVGAVVVKPCPKYFRFLTTFLGNVSRNCTSQGWTDVYPAPYAVACGYDSNSTPGEEQTAFYGTVKTGYTIGHTLSLIALTAAMIILCLFRKLHCTRNYIHMHLFMSFIMRAIAVFIKDVILFESGEPEHCFVSSVGCKAMMVFFQYCVMANFFWLLVEGLYLHTLLVISFFSERKYFWWYILIGWGAPSVFITAWTVVRIYFFNVGCWEEIIETPIWWIIKTPILVSILVNFILFICIIRILVQKLHSPDVGHNETSQYSRLAKSTLLLIPLFGIHYIMFAFFPDNFKAEVKLVFELVVGSFQGFVVAVLYCFLNGEVQAELKRKWRRWHLERFLGSDMKYHHPSLGSNGTNFSTQISMLTKCSPKTRRCSSFQAEFSLV", "length": 428, "header": "tr|A0A8V1A401-1|A0A8V1A8V6_CHICK Computationally mapped isoform of Vasoactive intestinal peptide receptor 1 OS=Gallus gallus OX=9031 GN=VIPR1 PE=3 SV=1 CANONICAL=A0A8V1A8V6-1" }, "locus": { "chromosome": "2", "start_pos": 1868651, "end_pos": 1763640, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066345.1", "url": "https://www.ensembl.org/id/ENSGALT00010066345.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040611.1", "url": "https://www.ensembl.org/id/ENSGALP00010040611.1" } ] } }, { "isoform_ac": "A0A8V1A8V1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8V6/entry#A0A8V1A8V1-1", "sequence": { "sequence": "MDKVSFSASSTRPECSIMLEIEEERSQCLAEITEDNQTSGCRRQWDNITCWPEAQVGAVVVKPCPKYFRFLTTFLGNVSRNCTSQGWTDVYPAPYAVACGYDSNSTPGEEQTAFYGTVKTGYTIGHTLSLIALTAAMIILCLFRKLHCTRNYIHMHLFMSFIMRAIAVFIKDVILFESGEPEHCFVSSVGCKAMMVFFQYCVMANFFWLLVEGLYLHTLLVISFFSERKYFWWYILIGWGAPSVFITAWTVVRIYFFNVGCWEEIIETPIWWIIKTPILVSILVNFILFICIIRILVQKLHSPDVGHNETSQYSRLAKSTLLLIPLFGIHYIMFAFFPDNFKAEVKLVFELVVGSFQGFVVAVLYCFLNGEVQAELKRKWRRWHLERFLGSDMKYHHPSLGSNGTNFSTQISMLTKCSPKTRRCSSFQAEFSLV", "length": 434, "header": "tr|A0A8V1A8V1-1|A0A8V1A8V1_CHICK Computationally mapped isoform of Vasoactive intestinal peptide receptor 1 OS=Gallus gallus OX=9031 GN=VIPR1 PE=3 SV=1 CANONICAL=A0A8V1A8V6-1" }, "locus": { "chromosome": "2", "start_pos": 1868651, "end_pos": 1798430, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066337.1", "url": "https://www.ensembl.org/id/ENSGALT00010066337.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040603.1", "url": "https://www.ensembl.org/id/ENSGALP00010040603.1" } ] } }, { "isoform_ac": "A0A8V1A8V6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8V6/entry#A0A8V1A8V6-1", "sequence": { "sequence": "MRATGAHVLERSAALRHGTERSELGGARCPRHAIRSAARPPAAARLPPIRGCRRQWDNITCWPEAQVGAVVVKPCPKYFRFLTTFLGNVSRNCTSQGWTDVYPAPYAVACGYDSNSTPGEEQTAFYGTVKTGYTIGHTLSLIALTAAMIILCLFRKLHCTRNYIHMHLFMSFIMRAIAVFIKDVILFESGEPEHCFVSSVGCKAMMVFFQYCVMANFFWLLVEGLYLHTLLVISFFSERKYFWWYILIGWGAPSVFITAWTVVRIYFFNVGCWEEIIETPIWWIIKTPILVSILVNFILFICIIRILVQKLHSPDVGHNETSQYSRLAKSTLLLIPLFGIHYIMFAFFPDNFKAEVKLVFELVVGSFQGFVVAVLYCFLNGEVQAELKRKWRRWHLERFLGSDMKYHHPSLGSNGTNFSTQISMLTKCSPKTRRCSSFQAEFSLV", "length": 445, "header": "tr|A0A8V1A8V6-1|A0A8V1A8V6_CHICK Isoform 1 of Vasoactive intestinal peptide receptor 1 OS=Gallus gallus OX=9031 GN=VIPR1 PE=3 SV=1 CANONICAL=A0A8V1A8V6-1" }, "locus": { "chromosome": "2", "start_pos": 1868651, "end_pos": 1764351, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066342.1", "url": "https://www.ensembl.org/id/ENSGALT00010066342.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040608.1", "url": "https://www.ensembl.org/id/ENSGALP00010040608.1" } ] } }, { "isoform_ac": "A0A8V1ABK1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8V6/entry#A0A8V1ABK1-1", "sequence": { "sequence": "MQSARLRVLLPLLGCLLSAASSTRPECSIMLEIEEERSQCLAEITEDNQTSGCRRQWDNITCWPEAQVGAVVVKPCPKYFRFLTTFLGNVSRNCTSQGWTDVYPAPYAVACGYDSNSTPGEEQTAFYGTVKTGYTIGHTLSLIALTAAMIILCLFRKLHCTRNYIHMHLFMSFIMRAIAVFIKDVILFESGEPEHCFVSSVGCKAMMVFFQYCVMANFFWLLVEGLYLHTLLVISFFSERKYFWWYILIGWGAPSVFITAWTVVRIYFFNVGCWEEIIETPIWWIIKTPILVSILVNFILFICIIRILVQKLHSPDVGHNETSQYSRLAKSTLLLIPLFGIHYIMFAFFPDNFKAEVKLVFELVVGSFQVNMPSVQAELKRKWRRWHLERFLGSDMKYHHPSLGSNGTNFSTQISMLTKCSPKTRRCSSFQAEFSLV", "length": 437, "header": "tr|A0A8V1ABK1-1|A0A8V1A8V6_CHICK Computationally mapped isoform of Vasoactive intestinal peptide receptor 1 OS=Gallus gallus OX=9031 GN=VIPR1 PE=3 SV=1 CANONICAL=A0A8V1A8V6-1" }, "locus": { "chromosome": "2", "start_pos": 1868651, "end_pos": 1764445, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066339.1", "url": "https://www.ensembl.org/id/ENSGALT00010066339.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040605.1", "url": "https://www.ensembl.org/id/ENSGALP00010040605.1" } ] } }, { "isoform_ac": "A0A8V1AEA8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8V6/entry#A0A8V1AEA8-1", "sequence": { "sequence": "MPKVLQVPHHFSRNSAILHRERSILALDVMRHAGNVSRNCTSQGWTDVYPAPYAVACGYDSNSTPGEEQTAFYGTVKTGYTIGHTLSLIALTAAMIILCLFRKLHCTRNYIHMHLFMSFIMRAIAVFIKDVILFESGEPEHCFVSSVGCKAMMVFFQYCVMANFFWLLVEGLYLHTLLVISFFSERKYFWWYILIGWGAPSVFITAWTVVRIYFFNVGCWEEIIETPIWWIIKTPILVSILVNFILFICIIRILVQKLHSPDVGHNETSQYSRLAKSTLLLIPLFGIHYIMFAFFPDNFKAEVKLVFELVVGSFQGFVVAVLYCFLNGEVQAELKRKWRRWHLERFLGSDMKYHHPSLGSNGTNFSTQISMLTKCSPKTRRCSSFQAEFSLV", "length": 392, "header": "tr|A0A8V1AEA8-1|A0A8V1AEA8_CHICK Computationally mapped isoform of Vasoactive intestinal peptide receptor 1 OS=Gallus gallus OX=9031 GN=VIPR1 PE=3 SV=1 CANONICAL=A0A8V1A8V6-1" }, "locus": { "chromosome": "2", "start_pos": 1868651, "end_pos": 1821556, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066348.1", "url": "https://www.ensembl.org/id/ENSGALT00010066348.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040614.1", "url": "https://www.ensembl.org/id/ENSGALP00010040614.1" } ] } }, { "isoform_ac": "A0A8V1AGA5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8V6/entry#A0A8V1AGA5-1", "sequence": { "sequence": "MHIPMASSTRPECSIMLEIEEERSQCLAEITEDNQTSGCRRQWDNITCWPEAQVGAVVVKPCPKYFRFLTTFLGNVSRNCTSQGWTDVYPAPYAVACGYDSNSTPGEEQTAFYGTVKTGYTIGHTLSLIALTAAMIILCLFRKLHCTRNYIHMHLFMSFIMRAIAVFIKDVILFESGEPEHCFVSSVGCKAMMVFFQYCVMANFFWLLVEGLYLHTLLVISFFSERKYFWWYILIGWGAPSVFITAWTVVRIYFFNVGCWEEIIETPIWWIIKTPILVSILVNFILFICIIRILVQKLHSPDVGHNETSQYSRLAKSTLLLIPLFGIHYIMFAFFPDNFKAEVKLVFELVVGSFQGFVVAVLYCFLNGEVQAELKRKWRRWHLERFLGSDMKYHHPSLGSNGTNFSTQISMLTKCSPKTRRCSSFQAEFSLV", "length": 432, "header": "tr|A0A8V1AGA5-1|A0A8V1A8V6_CHICK Computationally mapped isoform of Vasoactive intestinal peptide receptor 1 OS=Gallus gallus OX=9031 GN=VIPR1 PE=3 SV=1 CANONICAL=A0A8V1A8V6-1" }, "locus": { "chromosome": "2", "start_pos": 1868651, "end_pos": 1803022, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066336.1", "url": "https://www.ensembl.org/id/ENSGALT00010066336.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040602.1", "url": "https://www.ensembl.org/id/ENSGALP00010040602.1" } ] } }, { "isoform_ac": "R4GKH9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8V6/entry#R4GKH9-1", "sequence": { "sequence": "MQSARLRVLLPLLGCLLSAASSTRPECSIMLEIEEERSQCLAEITEDNQTSGNVSRNCTSQGWTDVYPAPYAVACGYDSNSTPGEEQTAFYGTVKTGYTIGHTLSLIALTAAMIILCLFRKLHCTRNYIHMHLFMSFIMRAIAVFIKDVILFESGEPEHCFVSSVGCKAMMVFFQYCVMANFFWLLVEGLYLHTLLVISFFSERKYFWWYILIGWGAPSVFITAWTVVRIYFFNVGCWEEIIETPIWWIIKTPILVSILVNFILFICIIRILVQKLHSPDVGHNETSQYSRLAKSTLLLIPLFGIHYIMFAFFPDNFKAEVKLVFELVVGSFQGFVVAVLYCFLNGEVQAELKRKWRRWHLERFLGSDMKYHHPSLGSNGTNFSTQISMLTKCSPKTRRCSSFQAEFSLV", "length": 410, "header": "tr|R4GKH9-1|A0A8V1A8V6_CHICK Computationally mapped isoform of Vasoactive intestinal peptide receptor 1 OS=Gallus gallus OX=9031 GN=VIPR1 PE=3 SV=1 CANONICAL=A0A8V1A8V6-1" }, "locus": { "chromosome": "2", "start_pos": 1868651, "end_pos": 1764445, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066338.1", "url": "https://www.ensembl.org/id/ENSGALT00010066338.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040604.1", "url": "https://www.ensembl.org/id/ENSGALP00010040604.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-418555", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-418555", "resource": "Reactome", "description": "G alpha (s) signalling events" }, { "id": "R-GGA-420092", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-420092", "resource": "Reactome", "description": "Glucagon-type ligand receptors" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A8V6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8V6" } ], "pmid": "" }, { "name": "receptor complex", "id": "GO:0043235", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043235", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A8V6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8V6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "cell surface receptor signaling pathway", "id": "GO:0007166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007166", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A8V6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8V6" } ], "pmid": "" }, { "name": "adenylate cyclase-activating G protein-coupled receptor signaling pathway", "id": "GO:0007189", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007189", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A8V6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8V6" } ], "pmid": "" }, { "name": "G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger", "id": "GO:0007187", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007187", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A8V6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8V6" } ], "pmid": "" }, { "name": "adenylate cyclase-modulating G protein-coupled receptor signaling pathway", "id": "GO:0007188", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007188", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A8V6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8V6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "vasoactive intestinal polypeptide receptor activity", "id": "GO:0004999", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004999", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A8V6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8V6" } ], "pmid": "" }, { "name": "pituitary adenylate cyclase-activating polypeptide receptor activity", "id": "GO:0001634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A8V6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8V6" } ], "pmid": "" }, { "name": "peptide hormone binding", "id": "GO:0017046", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017046", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A8V6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8V6" } ], "pmid": "" }, { "name": "G protein-coupled peptide receptor activity", "id": "GO:0008528", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008528", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A8V6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8V6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 115, "end_pos": 117, "annotation": "n_glycosylation_sequon" }, { "start_pos": 319, "end_pos": 321, "annotation": "n_glycosylation_sequon" }, { "start_pos": 414, "end_pos": 416, "annotation": "n_glycosylation_sequon" }, { "start_pos": 417, "end_pos": 419, "annotation": "n_glycosylation_sequon" }, { "start_pos": 58, "end_pos": 60, "annotation": "n_glycosylation_sequon" }, { "start_pos": 88, "end_pos": 90, "annotation": "n_glycosylation_sequon" }, { "start_pos": 92, "end_pos": 94, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1A8V6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8V6" }, { "id": "PS50227", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50227" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 2 profile 1", "eco_id": "ECO_0000259", "start_pos": 28, "end_pos": 114, "start_aa": "Arg", "end_aa": "Ser", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1A8V6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8V6" }, { "id": "PS50261", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50261" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 2 profile 2", "eco_id": "ECO_0000259", "start_pos": 129, "end_pos": 380, "start_aa": "Val", "end_aa": "Asn", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 115, "end_pos": 117 }, { "start_pos": 319, "end_pos": 321 }, { "start_pos": 414, "end_pos": 416 }, { "start_pos": 417, "end_pos": 419 }, { "start_pos": 58, "end_pos": 60 }, { "start_pos": 88, "end_pos": 90 }, { "start_pos": 92, "end_pos": 94 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", 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"database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A8J2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8J2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AG84", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG84", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AG84-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG84-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AKC3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKC3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AKC3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKC3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLDQSYCHRLQHDMYFLTSNSRLNEQVVDKIILQLNRVYPQILTNTEAEKFRNPKASLHTRLSDLIKHLQKKGERHCQEFYRALQINAEQLYDDLPSRKILKTTDSAEIDTDKEKCMLNDRGPVFFLACFSAAAGFALFWYCCNSDAKVIGRSRRILGFSPIIIGRHVRNICMLYLEDISRN", "length": 182, "header": "tr|A0A8V1A8J2-1|A0A8V1A8J2_CHICK Isoform 1 of Caspase recruitment domain-containing protein 19 OS=Gallus gallus OX=9031 GN=CARD19 PE=1 SV=1 CANONICAL=A0A8V1A8J2-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A8J2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8J2/entry#A0A8V1A8J2-1", "sequence": { "sequence": "MLDQSYCHRLQHDMYFLTSNSRLNEQVVDKIILQLNRVYPQILTNTEAEKFRNPKASLHTRLSDLIKHLQKKGERHCQEFYRALQINAEQLYDDLPSRKILKTTDSAEIDTDKEKCMLNDRGPVFFLACFSAAAGFALFWYCCNSDAKVIGRSRRILGFSPIIIGRHVRNICMLYLEDISRN", "length": 182, "header": "tr|A0A8V1A8J2-1|A0A8V1A8J2_CHICK Isoform 1 of Caspase recruitment domain-containing protein 19 OS=Gallus gallus OX=9031 GN=CARD19 PE=1 SV=1 CANONICAL=A0A8V1A8J2-1" }, "locus": { "chromosome": "12", "start_pos": 6832444, "end_pos": 6819497, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068832.1", "url": "https://www.ensembl.org/id/ENSGALT00010068832.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042274.1", "url": "https://www.ensembl.org/id/ENSGALP00010042274.1" } ] } }, { "isoform_ac": "A0A8V1AG84-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8J2/entry#A0A8V1AG84-1", "sequence": { "sequence": "MEIGVGLNLSVCIFSAASGEFVMDVGRRTRLEAAAVCQVPHLSSDQSYCHRLQHDMYFLTSNSRLNEQVVDKIILQLNRVYPQILTNTEAEKFRNPKASLHTRLSDLIKHLQKKGERHCQEFYRALQINAEQLYDDLPSRKILKTTDSAEIDTDKEKCMLNDRGPVFFLACFSAAAGFALFWYCCNSDAKVIGRSRRILGFSPIIIGRHVRNICMLYLEDISRN", "length": 224, "header": "tr|A0A8V1AG84-1|A0A8V1A8J2_CHICK Computationally mapped isoform of Caspase recruitment domain-containing protein 19 OS=Gallus gallus OX=9031 GN=CARD19 PE=1 SV=1 CANONICAL=A0A8V1A8J2-1" }, "locus": { "chromosome": "12", "start_pos": 6831932, "end_pos": 6819497, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068831.1", "url": "https://www.ensembl.org/id/ENSGALT00010068831.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042273.1", "url": "https://www.ensembl.org/id/ENSGALP00010042273.1" } ] } }, { "isoform_ac": "A0A8V1AKC3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8J2/entry#A0A8V1AKC3-1", "sequence": { "sequence": "MLYRSHWEEAGGNSHGFGIGRRETHGCPPCGNSSGWTAQELSPAVPVLWKQLLPSDQSYCHRLQHDMYFLTSNSRLNEQVVDKIILQLNRVYPQILTNTEAEKFRNPKASLHTRLSDLIKHLQKKGERHCQEFYRALQINAEQLYDDLPSRKILKTTDSAEIDTDKEKCPVFFLACFSAAAGFALFWYCCNSDAKVIGRSRRILGFSPIIIGRHVRNICMLYLEDISRN", "length": 229, "header": "tr|A0A8V1AKC3-1|A0A8V1A8J2_CHICK Computationally mapped isoform of Caspase recruitment domain-containing protein 19 OS=Gallus gallus OX=9031 GN=CARD19 PE=1 SV=1 CANONICAL=A0A8V1A8J2-1" }, "locus": { "chromosome": "12", "start_pos": 6834781, "end_pos": 6819497, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068833.1", "url": "https://www.ensembl.org/id/ENSGALT00010068833.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042275.1", "url": "https://www.ensembl.org/id/ENSGALP00010042275.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:415987", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415987", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "mitochondrial membrane", "id": "GO:0031966", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031966", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A8J2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8J2" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A8J2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8J2" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A8J2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8J2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of apoptotic process", "id": "GO:0042981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042981", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A8J2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8J2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1A8J2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8J2" }, { "id": "PS50209", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50209" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CARD", "eco_id": "ECO_0000259", "start_pos": 2, "end_pos": 99, "start_aa": "Leu", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A8P8-1", "uniprot_ac": "A0A8V1A8P8", "uniprot_id": "A0A8V1A8P8_CHICK", "mass": { "chemical_mass": 26282.0, "monoisotopic_mass": 26282.0 }, "refseq": { "ac": "XP_015154044", "name": "chromatin target of PRMT1 protein isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015154044" }, "gene_names": [ { "name": "CHTOP", "type": "recommended", "evidence": [ { "id": "A0A8V1A8P8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8P8" } ] }, { "name": "CHTOP", "type": "synonym", "evidence": [ { "id": "XP_015154044", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015154044" } ] } ], "protein_names": [ { "name": "Chromatin target of PRMT1", "type": "synonym", "evidence": [ { "id": "A0A8V1A8P8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8P8/entry#names_and_taxonomy" } ] }, { "name": "chromatin target of PRMT1 protein isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015154044", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015154044" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052556.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015154044", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015154044" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A8P8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8P8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CHTOP", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8P8", "locus": { "chromosome": "25", "start_pos": 1745956, "end_pos": 1739934, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028442", "url": "https://www.ensembl.org/id/ENSGALG00010028442" } ] } } ], "crossref": [ { "id": "A0A8V1A8P8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A8P8", "database": "AlphaFoldDB", "categories": [] }, { "id": "426357", "url": "https://www.ncbi.nlm.nih.gov/gene/426357", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR025715", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025715", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052656", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052656", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "KIQMQRQ", "url": "https://omabrowser.org/oma/group/KIQMQRQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A8P8", "url": "https://www.orthodb.org/?gene=A0A8V1A8P8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AGD0", "url": "https://www.orthodb.org/?gene=A0A8V1AGD0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AIM2", "url": "https://www.orthodb.org/?gene=A0A8V1AIM2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AKF9", "url": "https://www.orthodb.org/?gene=A0A8V1AKF9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48426", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48426", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR48426:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48426:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13865", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13865", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015154044", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015154044", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1A8P8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8P8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A8P8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8P8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGD0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGD0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGD0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGD0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AIM2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIM2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AIM2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIM2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AKF9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKF9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AKF9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKF9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAQSAPKVVLKSTTKMSLNERFTNMLKNKQPMPVNIRATMQQQQQLASARNRRLAQQMENRPSVQAALKLKQKSLKQRLGKSNIQARLGRPAGPIARGAMGGRGLAMGQRGLPRGAMRGGRGGRALLRGGLPLRGQGLLRGGRGMAPRMGLRRGGLRGRGGPGRGAMGRGAMGRGGLGGRGRGMAGRGRGGFGGRGRGRGRGRGSARPALTKEQLDNQLDAYMSKTKGHLDAELDAYMAQTDPETND", "length": 248, "header": "tr|A0A8V1A8P8-1|A0A8V1A8P8_CHICK Isoform 1 of Chromatin target of PRMT1 OS=Gallus gallus OX=9031 GN=CHTOP PE=1 SV=1 CANONICAL=A0A8V1A8P8-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A8P8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8P8/entry#A0A8V1A8P8-1", "sequence": { "sequence": "MAAQSAPKVVLKSTTKMSLNERFTNMLKNKQPMPVNIRATMQQQQQLASARNRRLAQQMENRPSVQAALKLKQKSLKQRLGKSNIQARLGRPAGPIARGAMGGRGLAMGQRGLPRGAMRGGRGGRALLRGGLPLRGQGLLRGGRGMAPRMGLRRGGLRGRGGPGRGAMGRGAMGRGGLGGRGRGMAGRGRGGFGGRGRGRGRGRGSARPALTKEQLDNQLDAYMSKTKGHLDAELDAYMAQTDPETND", "length": 248, "header": "tr|A0A8V1A8P8-1|A0A8V1A8P8_CHICK Isoform 1 of Chromatin target of PRMT1 OS=Gallus gallus OX=9031 GN=CHTOP PE=1 SV=1 CANONICAL=A0A8V1A8P8-1" }, "locus": { "chromosome": "25", "start_pos": 1745350, "end_pos": 1741227, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068888.1", "url": "https://www.ensembl.org/id/ENSGALT00010068888.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042330.1", "url": "https://www.ensembl.org/id/ENSGALP00010042330.1" } ] } }, { "isoform_ac": "A0A8V1AGD0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8P8/entry#A0A8V1AGD0-1", "sequence": { "sequence": "MAAQSAPKVVLKSTTKMSLNERFTNMLKNKQPMPVNIRATMQQQQQLASARNRRLAQQMENRPSVQAALKLKQKSLKQRLGKSNIQARLGRPAGPIARGAMGGRGLAMGQRGLPRGAMRGGRGGRALLRGGLPLRGQPWHGGPGKRRLRRPWQRQRTGQRISTARADQGAAGQPVGCLHVENKRTPGRRAGRLHGSDRPRNERLKGVCRDCCGSRCGFHTHKLNKQKRKPRLTPEGPGGTGSSPVLPQIRLQYVFLSCFDTLCCVKPFGIIFIYYSLPPPPPPPTVRI", "length": 288, "header": "tr|A0A8V1AGD0-1|A0A8V1A8P8_CHICK Computationally mapped isoform of Chromatin target of PRMT1 OS=Gallus gallus OX=9031 GN=CHTOP PE=1 SV=1 CANONICAL=A0A8V1A8P8-1" }, "locus": { "chromosome": "25", "start_pos": 1745604, "end_pos": 1741227, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068887.1", "url": "https://www.ensembl.org/id/ENSGALT00010068887.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042329.1", "url": "https://www.ensembl.org/id/ENSGALP00010042329.1" } ] } }, { "isoform_ac": "A0A8V1AIM2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8P8/entry#A0A8V1AIM2-1", "sequence": { "sequence": "MLRGVVWMLLHGLQLLGIGWTRLRLDSVDLKMAAQSAPKVVLKSTTKMSLNERFTNMLKNKQPMPVNIRATMQQQQQLASARNRRLAQQMENRPSVQAALKLKQKSLKQRLGKSNIQARLGRPAGPIARGAMGGRGLAMGQRGLPRGAMRGGRGGRALLRGGLPLRGQGLLRGGRGMAPRMGLRRGGLRGRGGPGRGAMGRGAMGRGGLGGRGRGMAGRGRGGFGGRGRGRGRGRGSARPALTKEQLDNQLDAYMSKTKGHLDAELDAYMAQTDPETND", "length": 279, "header": "tr|A0A8V1AIM2-1|A0A8V1A8P8_CHICK Computationally mapped isoform of Chromatin target of PRMT1 OS=Gallus gallus OX=9031 GN=CHTOP PE=1 SV=1 CANONICAL=A0A8V1A8P8-1" }, "locus": { "chromosome": "25", "start_pos": 1745350, "end_pos": 1740235, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068886.1", "url": "https://www.ensembl.org/id/ENSGALT00010068886.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042328.1", "url": "https://www.ensembl.org/id/ENSGALP00010042328.1" } ] } }, { "isoform_ac": "A0A8V1AKF9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8P8/entry#A0A8V1AKF9-1", "sequence": { "sequence": "MAAQSAPKVVLKSTTKMSLNERFTNMLKNKQPMPVNIRATMQQQQQLASARNRRLAQQMENRPSVQAALKLKQSLKQRLGKSNIQARLGRPAGPIARGAMGGRGLAMGQSSAERRAPTARSGPAAGRPRNGPQDGAEKRRAAGPRGAGQRRYGAWSHGAWRTRRQRPWHGGPGKRRLRRPWQRQRTGQRISTARADQGAAGQPVGCLHVENKRTPGRRAGRLHGSDRPRNERLKGVCRDCCGSRCGFHTHKLNKQKRKPRLTPEGPGGTGSSPVLPQIRLQYVFLSCFDTLCCVKPFGIIFIYYSLPPPPPPPTVRI", "length": 317, "header": "tr|A0A8V1AKF9-1|A0A8V1A8P8_CHICK Computationally mapped isoform of Chromatin target of PRMT1 OS=Gallus gallus OX=9031 GN=CHTOP PE=1 SV=1 CANONICAL=A0A8V1A8P8-1" }, "locus": { "chromosome": "25", "start_pos": 1745604, "end_pos": 1741227, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068889.1", "url": "https://www.ensembl.org/id/ENSGALT00010068889.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042331.1", "url": "https://www.ensembl.org/id/ENSGALP00010042331.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "G3HC20-1", "protein_name": "Chromatin target of PRMT1 protein isoform X2", "gene_name": "Chtop", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAAQSAPKVVLKSTTKMSLNERFTNMLKNKQPMPVNIRASMQQQQQLASARNRRLAQQMENRPSVQAALKLKQKSLKQRLGKSNIQARLGRPIGTLARGAIGGRSLPIIQRGLPRGGLRGGRSTRSLLRGGISLRGQNLLRGGRAVAPRMGLRRGGVRGRGGPGRGGLGRGAMGRGGIGGRGRGMIGRGRGGFGGRGRGRGRGRGALTRPVLTKEQLDNQLDAYMSKTKGHLDAELDAYMAQTDPETND", "length": 249 }, "evidence": [ { "id": "A0A8V1A8P8", "url": "https://omabrowser.org/oma/group/A0A8V1A8P8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q3SYW9-1", "protein_name": "Chromatin target of PRMT1 protein", "gene_name": "CHTOP", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAAQSAPKVVLKSTTKMSLNERFTNMLKNKQPMPVNIRASMQQQQQLASARNRRLAQQMENRPSVQAALKLKQSLKQRLGKSNIQARLGRPIGALARGAIGGRGLPIIQRGLPRGGLRGGRATRTLLRGGMSLRGQNLLRGGRAVAPRMGLRRGGVRGRGGPGRGGLGRGAMGRGGIGGRGRGMIGRGRGGFGGRGRGRGRGRGALARPVLTKEQLDNQLDAYMSKTKGHLDAELDAYMAQTDPETND", "length": 248 }, "evidence": [ { "id": "A0A8V1A8P8", "url": "https://omabrowser.org/oma/group/A0A8V1A8P8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q498T2-1", "protein_name": "Chromatin target of PRMT1 protein", "gene_name": "Chtop", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAQSAPKVVLKSTTKMSLNERFTNMLKNKQPMPVNIWASMQQQQQLASARNRRLAQQMENRPSVQAALKLKQSLKQRLGKSNIQARLGRPIGALARGAIGGRSLPIIQRGLPRGGLRGGRATRTLLRGGMSLRGQNLLRGGRAVAPRMGLRRGGVRGRGGPGRGGLGRGAMGRGGIGGRGRGMIGRGRGGFGGRGRGRGRGRGALTRPVLTKEQLDNQLDAYMSKTKGHLDAELDAYMAQTDPETND", "length": 248 }, "evidence": [ { "id": "A0A8V1A8P8", "url": "https://omabrowser.org/oma/group/A0A8V1A8P8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9CY57-1", "protein_name": "Chromatin target of PRMT1 protein", "gene_name": "Chtop", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAQSAPKVVLKSTTKMSLNERFTNMLKNKQPMPVNIRASMQQQQQLASARNRRLAQQMENRPSVQAALKLKQKSLKQRLGKSNIQARLGRPIGALARGAIGGRGLPIIQRGLPRGGLRGGRATRTLLRGGMSLRGQNLLRGGRAVAPRMGLRRGGVRGRGGPGRGGLGRGAMGRGGIGGRGRGMIGRGRGGFGGRGRGRGRGRGALTRPVLTKEQLDNQLDAYMSKTKGHLDAELDAYMAQTDPETND", "length": 249 }, "evidence": [ { "id": "A0A8V1A8P8", "url": "https://omabrowser.org/oma/group/A0A8V1A8P8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9Y3Y2-1", "protein_name": "Chromatin target of PRMT1 protein", "gene_name": "CHTOP", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAQSAPKVVLKSTTKMSLNERFTNMLKNKQPTPVNIRASMQQQQQLASARNRRLAQQMENRPSVQAALKLKQSLKQRLGKSNIQARLGRPIGALARGAIGGRGLPIIQRGLPRGGLRGGRATRTLLRGGMSLRGQNLLRGGRAVAPRMGLRRGGVRGRGGPGRGGLGRGAMGRGGIGGRGRGMIGRGRGGFGGRGRGRGRGRGALARPVLTKEQLDNQLDAYMSKTKGHLDAELDAYMAQTDPETND", "length": 248 }, "evidence": [ { "id": "A0A8V1A8P8", "url": "https://omabrowser.org/oma/group/A0A8V1A8P8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A8P8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8P8" } ], "pmid": "" }, { "name": "methyl-CpG binding", "id": "GO:0008327", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008327", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A8P8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8P8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "chromatin remodeling", "id": "GO:0006338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006338", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A8P8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8P8" } ], "pmid": "" }, { "name": "mRNA export from nucleus", "id": "GO:0006406", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006406", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A8P8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8P8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A8P8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8P8" } ], "pmid": "" }, { "name": "transcription export complex", "id": "GO:0000346", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000346", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A8P8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8P8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1A8P8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8P8" }, { "id": "SM01218", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM01218" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Chromatin target of PRMT1 protein C-terminal", "eco_id": "ECO_0000259", "start_pos": 158, "end_pos": 245, "start_aa": "Arg", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A7R5-1", "uniprot_ac": "A0A8V1A7R5", "uniprot_id": "A0A8V1A7R5_CHICK", "mass": { "chemical_mass": 18297.0, "monoisotopic_mass": 18297.0 }, "refseq": {}, "gene_names": [ { "name": "LMO2", "type": "recommended", "evidence": [ { "id": "A0A8V1A7R5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7R5" } ] } ], "protein_names": [ { "name": "Rhombotin-2", "type": "recommended", "evidence": [ { "id": "A0A8V1A7R5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7R5/entry#names_and_taxonomy" } ] }, { "name": "LIM domain only protein 2", "type": "synonym", "evidence": [ { "id": "A0A8V1A7R5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7R5/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7R5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7R5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LMO2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7R5", "locus": { "chromosome": "5", "start_pos": 17957750, "end_pos": 17965222, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010024846", "url": "https://www.ensembl.org/id/ENSGALG00010024846" } ] } } ], "crossref": [ { "id": "A0A8V1A7R5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A7R5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000029892", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000029892", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd09384", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09384", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd09385", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09385", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001781", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001781", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050945", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050945", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5NYL8", "url": "https://www.orthodb.org/?gene=A0A1D5NYL8", "database": "OrthoDB", 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} ] }, { "name": "hydroxysteroid 11-beta-dehydrogenase 1-like protein isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015155167", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015155167" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052559.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015155167.2. 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"sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A889-1", "uniprot_ac": "A0A8V1A889", "uniprot_id": "A0A8V1A889_CHICK", "mass": { "chemical_mass": 90327.0, "monoisotopic_mass": 90327.0 }, "refseq": {}, "gene_names": [ { "name": "UBTF", "type": "recommended", "evidence": [ { "id": "A0A8V1A889", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A889" } ] } ], "protein_names": [ { "name": "Nucleolar transcription factor 1", "type": "recommended", "evidence": [ { "id": "A0A8V1A889", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A889/entry#names_and_taxonomy" } ] }, { "name": "Upstream-binding factor 1", "type": "synonym", "evidence": [ { "id": "A0A8V1A889", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A889/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A889", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A889" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "UBTF", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A889", "locus": { "chromosome": "27", "start_pos": 2685791, "end_pos": 2670728, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010024910", "url": "https://www.ensembl.org/id/ENSGALG00010024910" } ] } } ], "crossref": [ { "id": "A0A8V1A889", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A889", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd21998", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21998", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd21999", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21999", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd22000", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22000", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd22001", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22001", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd22002", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22002", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd22003", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22003", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100859792", "url": "https://www.ncbi.nlm.nih.gov/gene/100859792", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR009071", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009071", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029215", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029215", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036910", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036910", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051762", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051762", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:100859792", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100859792", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1A328", "url": "https://www.orthodb.org/?gene=A0A8V1A328", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A338", "url": "https://www.orthodb.org/?gene=A0A8V1A338", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A889", "url": "https://www.orthodb.org/?gene=A0A8V1A889", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A893", "url": "https://www.orthodb.org/?gene=A0A8V1A893", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A8A3", "url": "https://www.orthodb.org/?gene=A0A8V1A8A3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46318", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46318", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46318:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46318:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00505", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00505", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF09011", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09011", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14887", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14887", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-73728", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-73728", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-73762", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-73762", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-73772", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-73772", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-73863", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-73863", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1A328", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A328", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A328-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A328-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A338", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A338", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A338-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A338-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A889", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A889", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A889-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A889-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A893", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A893", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A893-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A893-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A8A3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8A3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A8A3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8A3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLTLLECMKNNLPSNDGSKFKTTESHLDWEKVAFKDFSGEMCKMKWMEISNEVRKFRTLTELIMDAEEHVKNPYKGKKLKKHPDFPKKPLTPYFRFFMEKRAKYAKLHPEMSNLDLTKILSKKYKELPEKKKMKYIQDFQREKQEFERNLARFREDHPDLIQNAKKSDVPEKPKTPQQLWYNHEKKIYLKVRPDATTKEVKESLGKQWSQLSDKKRLKWIHKALEQRKEYEEIMRDYIQKHPELNLSEEGITRSTLTKAERQLKDKFDGRPTKPPPNSYSLYCAELMANMKDVPSTERMVLCSQQWKLLSQKEKDAYHKKCDQKKKDYEIELLRFLESLPEEEQQRVLGEEKMLGSNRKGATSPASKKSSPETGKASSEKPKRPISAMFIFSEEKRKQLQEERPELSESELTRLLARMWNDLSEKKKAKYKAREAAMKAQSEKKHGSDKEERGKLPESPKTAEEIWQQSVIGDYLARFKNDRGKALKAMEATWNNMEKKEKLMWIKKAAEDQKRYERELSEMRAPPCSTNSAKKVKFQGEPKKPPMNGYQKFSQELLSNGELNHLPLKERMVEIGSRWQRISQGQKDHYKKLAEEQQKQYKVHLDIWLKSLSPQERAAYKEHTSNKRKSIGKIRGPNPKMKPTMQSKSESEDDDDDEEDEDDDDEDEDDDDDNGDSSEEGGDSSESSSEEESEDGDECECRVSEQRQSFAPVQLQSHYAGWRWGQKPCPCLVLAPGQNDEDDEDEDDEDEDDNDSEGSSSSSSSSGDSSDSDSN", "length": 774, "header": "tr|A0A8V1A889-1|A0A8V1A889_CHICK Isoform 1 of Nucleolar transcription factor 1 OS=Gallus gallus OX=9031 GN=UBTF PE=1 SV=1 CANONICAL=A0A8V1A889-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A328-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A889/entry#A0A8V1A328-1", "sequence": { "sequence": "MNGDTECPADLEMTAPKNQDRWSQEDMLTLLECMKNNLPSNDGSKFKTTESHLDWEKVAFKDFSGEMCKMKWMEISNEVRKFRTLTELIMDAEEHVKNPYKGKKLKKHPDFPKKPLTPYFRFFMEKRAKYAKLHPEMSNLDLTKILSKKYKELPEKKKMKYIQDFQREKQEFERNLARFREDHPDLIQNAKKSDVPEKPKTPQQLWYNHEKKIYLKVRPDEIMRDYIQKHPELNLSEEGITRSTLTKAERQLKDKFDGRPTKPPPNSYSLYCAELMANMKDVPSTERMVLCSQQWKLLSQKEKDAYHKKCDQKKKDYEIELLRFLESLPEEEQQRVLGEEKMLGSNRKGATSPASKKSSPETGKASSEKPKRPISAMFIFSEEKRKQLQEERPELSESELTRLLARMWNDLSEKKKAKYKAREAAMKAQSEKKHGSDKEERGKLPESPKTAEEIWQQSVIGDYLARFKNDRGKALKAMEATWNNMEKKEKLMWIKKAAEDQKRYERELSEMRAPPCSTNSAKKVKFQGEPKKPPMNGYQKFSQELLSNGELNHLPLKERMVEIGSRWQRISQGQKDHYKKLAEEQQKQYKVHLDIWLKSLSPQERAAYKEHTSNKRKSIGKIRGPNPKMKPTMQSKSESEDDDDDEEDEDDDDEDEDDDDDNGDSSEEGGDSSESSSEEESEDGDENDEDDEDEDDEDEDDNDSEGSSSSSSSSGDSSDSDSN", "length": 723, "header": "tr|A0A8V1A328-1|A0A8V1A889_CHICK Computationally mapped isoform of Nucleolar transcription factor 1 OS=Gallus gallus OX=9031 GN=UBTF PE=1 SV=1 CANONICAL=A0A8V1A889-1" }, "locus": { "chromosome": "27", "start_pos": 2684822, "end_pos": 2674854, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010060845.1", "url": "https://www.ensembl.org/id/ENSGALT00010060845.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010037602.1", "url": "https://www.ensembl.org/id/ENSGALP00010037602.1" } ] } }, { "isoform_ac": "A0A8V1A338-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A889/entry#A0A8V1A338-1", "sequence": { "sequence": "MNGDTECPADLEMTAPKNQDRWSQEDMLTLLECMKNNLPSNDGSKFKTTESHLDWEKVAFKDFSGEMCKMKWMEISNEVRKFRTLTELIMDAEEHVKNPYKGKKLKKHPDFPKKPLTPYFRFFMEKRAKYAKLHPEMSNLDLTKILSKKYKELPEKKKMKYIQDFQREKQEFERNLARFREDHPDLIQNAKKSDVPEKPKTPQQLWYNHEKKIYLKVRPDATTKEVKESLGKQWSQLSDKKRLKWIHKALEQRKEYEEIMRDYIQKHPELNLSEEGITRSTLTKAERQLKDKFDGRPTKPPPNSYSLYCAELMANMKDVPSTERMVLCSQQWKLLSQKEKDAYHKKCDQKKKDYEIELLRFLESLPEEEQQRVLGEEKMLGSNRKGATSPASKKSSPETGKASSEKPKRPISAMFIFSEEKRKQLQEERPELSESELTRLLARMWNDLSEKKKAKYKAREAAMKAQSEKKHGSDKEERGKLPESPKTAEEIWQQSVIGDYLARFKNDRGKALKAMEATWNNMEKKEKLMWIKKAAEDQKRYERELSEMRAPPCSTNSAKKVKFQGEPKKPPMNGYQKFSQELLSNGELNHLPLKERMVEIGSRWQRISQGQKDHYKKLAEEQQKQYKVHLDIWLKSLSPQERAAYKEHTSNKRKSIGKIRGPNPKMKPTMQSKSESEDDDDDEEDEDDDDEDEDDDDDNGDSSEEGGDSSESSSEEESEDGDENDEDDEDEDDEDEDDNDSEGSSSSSSSSGDSSDSDSN", "length": 760, "header": "tr|A0A8V1A338-1|A0A8V1A889_CHICK Computationally mapped isoform of Nucleolar transcription factor 1 OS=Gallus gallus OX=9031 GN=UBTF PE=1 SV=1 CANONICAL=A0A8V1A889-1" }, "locus": { "chromosome": "27", "start_pos": 2684822, "end_pos": 2674854, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010060855.1", "url": "https://www.ensembl.org/id/ENSGALT00010060855.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010037612.1", "url": "https://www.ensembl.org/id/ENSGALP00010037612.1" } ] } }, { "isoform_ac": "A0A8V1A889-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A889/entry#A0A8V1A889-1", "sequence": { "sequence": "MLTLLECMKNNLPSNDGSKFKTTESHLDWEKVAFKDFSGEMCKMKWMEISNEVRKFRTLTELIMDAEEHVKNPYKGKKLKKHPDFPKKPLTPYFRFFMEKRAKYAKLHPEMSNLDLTKILSKKYKELPEKKKMKYIQDFQREKQEFERNLARFREDHPDLIQNAKKSDVPEKPKTPQQLWYNHEKKIYLKVRPDATTKEVKESLGKQWSQLSDKKRLKWIHKALEQRKEYEEIMRDYIQKHPELNLSEEGITRSTLTKAERQLKDKFDGRPTKPPPNSYSLYCAELMANMKDVPSTERMVLCSQQWKLLSQKEKDAYHKKCDQKKKDYEIELLRFLESLPEEEQQRVLGEEKMLGSNRKGATSPASKKSSPETGKASSEKPKRPISAMFIFSEEKRKQLQEERPELSESELTRLLARMWNDLSEKKKAKYKAREAAMKAQSEKKHGSDKEERGKLPESPKTAEEIWQQSVIGDYLARFKNDRGKALKAMEATWNNMEKKEKLMWIKKAAEDQKRYERELSEMRAPPCSTNSAKKVKFQGEPKKPPMNGYQKFSQELLSNGELNHLPLKERMVEIGSRWQRISQGQKDHYKKLAEEQQKQYKVHLDIWLKSLSPQERAAYKEHTSNKRKSIGKIRGPNPKMKPTMQSKSESEDDDDDEEDEDDDDEDEDDDDDNGDSSEEGGDSSESSSEEESEDGDECECRVSEQRQSFAPVQLQSHYAGWRWGQKPCPCLVLAPGQNDEDDEDEDDEDEDDNDSEGSSSSSSSSGDSSDSDSN", "length": 774, "header": "tr|A0A8V1A889-1|A0A8V1A889_CHICK Isoform 1 of Nucleolar transcription factor 1 OS=Gallus gallus OX=9031 GN=UBTF PE=1 SV=1 CANONICAL=A0A8V1A889-1" }, "locus": { "chromosome": "27", "start_pos": 2684822, "end_pos": 2676027, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010060825.1", "url": "https://www.ensembl.org/id/ENSGALT00010060825.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010037584.1", "url": "https://www.ensembl.org/id/ENSGALP00010037584.1" } ] } }, { "isoform_ac": "A0A8V1A893-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A889/entry#A0A8V1A893-1", "sequence": { "sequence": "MNGDTECPADLEMTAPKNQDRWSQEDMLTLLECMKNNLPSNDGSKFKTTESHLDWEKVAFKDFSGEMCKMKWMEISNEVRKFRTLTELIMDAEEHVKNPYKGKKLKKHPDFPKKPLTPYFRFFMEKRAKYAKLHPEMSNLDLTKILSKKYKELPEKKKMKYIQDFQREKQEFERNLARFREDHPDLIQNAKKSDVPEKPKTPQQLWYNHEKKIYLKVRPDEIMRDYIQKHPELNLSEEGITRSTLTKAERQLKDKFDGRPTKPPPNSYSLYCAELMANMKDVPSTERMVLCSQQWKLLSQKEKDAYHKKCDQKKKDYEIELLRFLESLPEEEQQRVLGEEKMLGSNRKGATSPASKKSSPETGKASSEKPKRPISAMFIFSEEKRKQLQEERPELSESELTRLLARMWNDLSEKKKAKYKAREAAMKAQSEKKHGSDKEERGKLPESPKTAEEIWQQSVIGDYLARFKNDRGKALKAMEATWNNMEKKEKLMWIKKAAEDQKRYERELSEMRAPPCSTNSAKKVKFQGEPKKPPMNGYQKFSQELLSNGELNHLPLKERMVEIGSRWQRISQGQKDHYKKLAEEQQKQYKVHLDIWLKSLSPQERAAYKEHTSNKRKSIGKIRGPNPKMKPTMQSKSESEDDDDDEEDEDDDDEDEDDDDDNGDSSEEGGDSSESSSEEESEDGDECECRVSEQRQSFAPVQLQSHYAGWRWGQKPCPCLVLAPGQNDEDDEDEDDEDEDDNDSEGSSSSSSSSGDSSDSDSN", "length": 763, "header": "tr|A0A8V1A893-1|A0A8V1A893_CHICK Computationally mapped isoform of Nucleolar transcription factor 1 OS=Gallus gallus OX=9031 GN=UBTF PE=1 SV=1 CANONICAL=A0A8V1A889-1" }, "locus": { "chromosome": "27", "start_pos": 2684822, "end_pos": 2674854, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010060830.1", "url": "https://www.ensembl.org/id/ENSGALT00010060830.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010037589.1", "url": "https://www.ensembl.org/id/ENSGALP00010037589.1" } ] } }, { "isoform_ac": "A0A8V1A8A3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A889/entry#A0A8V1A8A3-1", "sequence": { "sequence": "MNGDTECPADLEMTAPKNQDRWSQEDMLTLLECMKNNLPSNDGSKFKTTESHLDWEKVAFKDFSGEMCKMKWMEISNEVRKFRTLTELIMDAEEHVKNPYKGKKLKKHPDFPKKPLTPYFRFFMEKRAKYAKLHPEMSNLDLTKILSKKYKELPEKKKMKYIQDFQREKQEFERNLARFREDHPDLIQNAKKSDVPEKPKTPQQLWYNHEKKIYLKVRPDATTKEVKESLGKQWSQLSDKKRLKWIHKALEQRKEYEEIMRDYIQKHPELNLSEEGITRSTLTKAERQLKDKFDGRPTKPPPNSYSLYCAELMANMKDVPSTERMVLCSQQWKLLSQKEKDAYHKKCDQKKKDYEIELLRFLESLPEEEQQRVLGEEKMLGSNRKGATSPASKKSSPETGKASSEKPKRPISAMFIFSEEKRKQLQEERPELSESELTRLLARMWNDLSEKKKAKYKAREAAMKAQSEKKHGSDKEERGKLPESPKTAEEIWQQSVIGDYLARFKNDRGKALKAMEATWNNMEKKEKLMWIKKAAEDQKRYERELSEMRAPPCSTNSAKKVKFQGEPKKPPMNGYQKFSQELLSNGELNHLPLKERMVEIGSRWQRISQGQKDHYKKLAEEQQKQYKVHLDIWLKSLSPQERAAYKEHTSNKRKSIGKIRGPNPKMKPTMQSKSESEDDDDDEEDEDDDDEDEDDDDDNGDSSEGGLLSVLLVVVVPLYFILFFIFFFLFIKRERS", "length": 736, "header": "tr|A0A8V1A8A3-1|A0A8V1A889_CHICK Computationally mapped isoform of Nucleolar transcription factor 1 OS=Gallus gallus OX=9031 GN=UBTF PE=1 SV=1 CANONICAL=A0A8V1A889-1" }, "locus": { "chromosome": "27", "start_pos": 2685791, "end_pos": 2674854, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010060842.1", "url": "https://www.ensembl.org/id/ENSGALT00010060842.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010037599.1", "url": "https://www.ensembl.org/id/ENSGALP00010037599.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:100859792", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100859792", "resource": "KEGG Pathway" }, { "id": "R-GGA-73728", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-73728", "resource": "Reactome", "description": "RNA Polymerase I Promoter Opening" }, { "id": "R-GGA-73762", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-73762", "resource": "Reactome", "description": "RNA Polymerase I Transcription Initiation" }, { "id": "R-GGA-73772", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-73772", "resource": "Reactome", "description": "RNA Polymerase I Promoter Escape" }, { "id": "R-GGA-73863", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-73863", "resource": "Reactome", "description": "RNA Polymerase I Transcription Termination" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A889", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A889" } ], "pmid": "" }, { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A889", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A889" } ], "pmid": "" }, { "name": "scaffold protein binding", "id": "GO:0097110", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097110", "evidence": [ { "database": 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"glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RASSF5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A796", "locus": { "chromosome": "26", "start_pos": 2542043, "end_pos": 2524035, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027117", "url": "https://www.ensembl.org/id/ENSGALG00010027117" } ] } } ], "crossref": [ { "id": "A0A8V1A796", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A796", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000038943", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000038943", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd17220", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17220", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd21892", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21892", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "419844", "url": "https://www.ncbi.nlm.nih.gov/gene/419844", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000159", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000159", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011524", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011524", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029071", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029071", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033614", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033614", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033623", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033623", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q3AME4", "url": "https://www.orthodb.org/?gene=A0A3Q3AME4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A283", "url": "https://www.orthodb.org/?gene=A0A8V1A283", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A288", "url": "https://www.orthodb.org/?gene=A0A8V1A288", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A796", "url": "https://www.orthodb.org/?gene=A0A8V1A796", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ACN8", "url": "https://www.orthodb.org/?gene=A0A8V1ACN8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AEQ3", "url": "https://www.orthodb.org/?gene=A0A8V1AEQ3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22738", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22738", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22738:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22738:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00788", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00788", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16517", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16517", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A3Q3AME4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3AME4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q3AME4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3AME4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A283", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A283", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A283-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A283-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A288", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A288", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A288-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A288-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A796", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A796", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A796-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A796-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ACN8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACN8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ACN8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACN8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AEQ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEQ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AEQ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEQ3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASLLQKKKCICQIDPQWLLSMLYLHGIRLRGGRRCSAQCCAALGVLVPVLRMSEGRAGAAACFGLIAKRIRKVFGHFPKSKSRSEGPRRLSRESSLLRDCRYTCHQQCHSLVQLDCRRPDPGQLSPEGTIVLPCSQNVTKAVEEKPEPPTVEEIKEKIEKYNAKVTNCLLMKLSDDGTYTGFIKVHLKLRRPVTVPAGIRPQSIYDALKEVNLADTTDRRTSFYLPLDAIKQLHISSTTTVSEVIQGLLKKFMVVDNPQKFALFKEMRKDGQVLLQKLPLTEFPLYLRLLAGPDTDVLSFVLKENETGEVEWDAFSIPELQNFLMILDKEEKDKIQQVKRKYEKFKQRLQQSLKEAGDKPG", "length": 362, "header": "tr|A0A8V1A796-1|A0A8V1A796_CHICK Isoform 1 of Ras association domain-containing protein 5 OS=Gallus gallus OX=9031 GN=RASSF5 PE=4 SV=1 CANONICAL=A0A8V1A796-1" }, "isoforms": [ { "isoform_ac": "A0A3Q3AME4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A796/entry#A0A3Q3AME4-1", "sequence": { "sequence": "MLSDCRYTCHQQCHSLVQLDCRRPDPGQLSPEGTIVLPCSQNVTKAVEEKPEPPTVEEIKEKIEKYNAKVTNCLLMKLSDDGTYTGFIKVHLKLRRPVTVPAGIRPQSIYDALKEVNLADTTDRRTSFYLPLDAIKQLHISSTTTVSEVIQGLLKKFMVVDNPQKFALFKEMRKDGQVLLQKLPLTEFPLYLRLLAGPDTDVLSFVLKENETGEVEWDAFSIPELQNFLMILDKEEKDKIQQVKRKYEKFKQRLQQSLKEAGDKPG", "length": 266, "header": "tr|A0A3Q3AME4-1|A0A8V1A796_CHICK Computationally mapped isoform of Ras association domain-containing protein 5 OS=Gallus gallus OX=9031 GN=RASSF5 PE=4 SV=1 CANONICAL=A0A8V1A796-1" }, "locus": { "chromosome": "26", "start_pos": 2539461, "end_pos": 2525550, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065737.1", "url": "https://www.ensembl.org/id/ENSGALT00010065737.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040003.1", "url": "https://www.ensembl.org/id/ENSGALP00010040003.1" } ] } }, { "isoform_ac": "A0A8V1A283-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A796/entry#A0A8V1A283-1", "sequence": { "sequence": "MAYSSSPGVSPGSALCTAAALRGALCLSPRIPFSNSSFTLCHPQRNPNVTKAVEEKPEPPTVEEIKEKIEKYNAKVTNCLLMKLVHLKLRRPVTVPAGIRPQSIYDALKEVNLADTTDRRTSFYLPLDAIKQLHISSTTTVSEVIQGLLKKFMVVDNPQKFALFKEMRKDGQVLLQKLPLTEFPLYLRLLAGPDTDVLSFVLKENETGEVEWDAFSIPELQNFLMILDKEEKDKIQQVKRKYEKFKQRLQQSLKEAGDKPG", "length": 261, "header": "tr|A0A8V1A283-1|A0A8V1A796_CHICK Computationally mapped isoform of Ras association domain-containing protein 5 OS=Gallus gallus OX=9031 GN=RASSF5 PE=4 SV=1 CANONICAL=A0A8V1A796-1" }, "locus": { "chromosome": "26", "start_pos": 2539461, "end_pos": 2536589, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065733.1", "url": "https://www.ensembl.org/id/ENSGALT00010065733.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039999.1", "url": "https://www.ensembl.org/id/ENSGALP00010039999.1" } ] } }, { "isoform_ac": "A0A8V1A288-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A796/entry#A0A8V1A288-1", "sequence": { "sequence": "MRAAFPVPSGGASRGERFHNSVDCRYTCHQQCHSLVQLDCRRPDPGQLSPEGTIVLPCSQNVTKAVEEKPEPPTVEEIKEKIEKYNAKVTNCLLMKLSDDGTYTGFIKVHLKLRRPVTVPAGIRPQSIYDALKEVNLADTTDRRTSFYLPLDAIKQLHISSTTTVSEVIQGLLKKFMVVDNPQKFALFKEMRKDGQVLLQKLPLTEFPLYLRLLAGPDTDVLSFVLKENETGEVEWDAFSIPELQNFLMILDKEEKDKIQQVKRKYEKFKQRLQQSLKEAGDKPG", "length": 285, "header": "tr|A0A8V1A288-1|A0A8V1A796_CHICK Computationally mapped isoform of Ras association domain-containing protein 5 OS=Gallus gallus OX=9031 GN=RASSF5 PE=4 SV=1 CANONICAL=A0A8V1A796-1" }, "locus": { "chromosome": "26", "start_pos": 2539461, "end_pos": 2524155, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065738.1", "url": "https://www.ensembl.org/id/ENSGALT00010065738.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040004.1", "url": "https://www.ensembl.org/id/ENSGALP00010040004.1" } ] } }, { "isoform_ac": "A0A8V1A796-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A796/entry#A0A8V1A796-1", "sequence": { "sequence": "MASLLQKKKCICQIDPQWLLSMLYLHGIRLRGGRRCSAQCCAALGVLVPVLRMSEGRAGAAACFGLIAKRIRKVFGHFPKSKSRSEGPRRLSRESSLLRDCRYTCHQQCHSLVQLDCRRPDPGQLSPEGTIVLPCSQNVTKAVEEKPEPPTVEEIKEKIEKYNAKVTNCLLMKLSDDGTYTGFIKVHLKLRRPVTVPAGIRPQSIYDALKEVNLADTTDRRTSFYLPLDAIKQLHISSTTTVSEVIQGLLKKFMVVDNPQKFALFKEMRKDGQVLLQKLPLTEFPLYLRLLAGPDTDVLSFVLKENETGEVEWDAFSIPELQNFLMILDKEEKDKIQQVKRKYEKFKQRLQQSLKEAGDKPG", "length": 362, "header": "tr|A0A8V1A796-1|A0A8V1A796_CHICK Isoform 1 of Ras association domain-containing protein 5 OS=Gallus gallus OX=9031 GN=RASSF5 PE=4 SV=1 CANONICAL=A0A8V1A796-1" }, "locus": { "chromosome": "26", "start_pos": 2539461, "end_pos": 2527970, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065735.1", "url": "https://www.ensembl.org/id/ENSGALT00010065735.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040001.1", "url": "https://www.ensembl.org/id/ENSGALP00010040001.1" } ] } }, { "isoform_ac": "A0A8V1ACN8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A796/entry#A0A8V1ACN8-1", "sequence": { "sequence": "METDTSGGFGSPDCRYTCHQQCHSLVQLDCRRPDPGQLSPEGTIVLPCSQNVTKAVEEKPEPPTVEEIKEKIEKYNAKVTNCLLMKLSDDGTYTGFIKVHLKLRRPVTVPAGIRPQSIYDALKEVNLADTTDRRTSFYLPLDAIKQLHISSTTTVSEVIQGLLKKFMVVDNPQKFALFKEMRKDGQVLLQKLPLTEFPLYLRLLAGPDTDVLSFVLKENETGEVEWDAFSIPELQNFLMILDKEEKDKIQQVKRKYEKFKQRLQQSLKEAGDKPG", "length": 275, "header": "tr|A0A8V1ACN8-1|A0A8V1ACN8_CHICK Computationally mapped isoform of Ras association domain-containing protein 5 OS=Gallus gallus OX=9031 GN=RASSF5 PE=4 SV=1 CANONICAL=A0A8V1A796-1" }, "locus": { "chromosome": "26", "start_pos": 2539461, "end_pos": 2527259, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065736.1", "url": "https://www.ensembl.org/id/ENSGALT00010065736.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040002.1", "url": "https://www.ensembl.org/id/ENSGALP00010040002.1" } ] } }, { "isoform_ac": "A0A8V1AEQ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A796/entry#A0A8V1AEQ3-1", "sequence": { "sequence": "MTIGSSMSSGYCSLDEDLEDCFFTAKTSFFRSAPSKGPAKNVTKAVEEKPEPPTVEEIKEKIEKYNAKVTNCLLMKLLLLAPWPEAPNPCRAVSPTHLPLCVIVQSDDGTYTGFIKVHLKLRRPVTVPAGIRPQSIYDALKEVNLADTTDRRTSFYLPLDAIKQLHISSTTTVSEVIQGLLKKFMVVDNPQKFALFKEMRKDGQVLLQKLPLTEFPLYLRLLAGPDTDVLSFVLKENETGEVEWDAFSIPELQNFLMILDKEEKDKIQQVKRKYEKFKQRLQQSLKEAGDKPG", "length": 293, "header": "tr|A0A8V1AEQ3-1|A0A8V1AEQ3_CHICK Computationally mapped isoform of Ras association domain-containing protein 5 OS=Gallus gallus OX=9031 GN=RASSF5 PE=4 SV=1 CANONICAL=A0A8V1A796-1" }, "locus": { "chromosome": "26", "start_pos": 2539461, "end_pos": 2532395, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065734.1", "url": "https://www.ensembl.org/id/ENSGALT00010065734.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040000.1", "url": "https://www.ensembl.org/id/ENSGALP00010040000.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A796", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A796" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A796", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A796" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A796", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A796" } ], "pmid": "" }, { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A796", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A796" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A796", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A796" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 138, "end_pos": 140, "annotation": "n_glycosylation_sequon" }, { "start_pos": 306, "end_pos": 308, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1A796", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A796" }, { "id": "PS50200", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50200" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ras-associating", "eco_id": "ECO_0000259", "start_pos": 222, "end_pos": 308, "start_aa": "Thr", "end_aa": "Thr", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1A796", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A796" }, { "id": "PS50951", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50951" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SARAH", "eco_id": "ECO_0000259", "start_pos": 310, "end_pos": 357, "start_aa": "Glu", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 138, "end_pos": 140 }, { "start_pos": 306, "end_pos": 308 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A9R5-1", "uniprot_ac": "A0A8V1A9R5", "uniprot_id": "A0A8V1A9R5_CHICK", "mass": { "chemical_mass": 64436.0, "monoisotopic_mass": 64436.0 }, "refseq": { "ac": "XP_015136574", "name": "kelch-like protein 18 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015136574" }, "gene_names": [ { "name": "KLHL18", "type": "recommended", "evidence": [ { "id": "A0A8V1A9R5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9R5" } ] }, { "name": "KLHL18", "type": "synonym", "evidence": [ { "id": "XP_015136574", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015136574" } ] } ], "protein_names": [ { "name": "Kelch like family member 18", "type": "synonym", "evidence": [ { "id": "A0A8V1A9R5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9R5/entry#names_and_taxonomy" } ] }, { "name": "kelch-like protein 18 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015136574", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015136574" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052533.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015136574.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015136574", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015136574" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9R5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9R5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "KLHL18", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9R5", "locus": { "chromosome": "2", "start_pos": 4006901, "end_pos": 3985254, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010025925", "url": "https://www.ensembl.org/id/ENSGALG00010025925" } ] } } ], "crossref": [ { "id": "A0A8V1A9R5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A9R5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000005582", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000005582", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd18247", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18247", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18457", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18457", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "420406", "url": "https://www.ncbi.nlm.nih.gov/gene/420406", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006652", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006652", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011705", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011705", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015915", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015915", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017096", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017096", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030603", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030603", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2TVA6", "url": "https://www.orthodb.org/?gene=A0A3Q2TVA6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q3AZL7", "url": "https://www.orthodb.org/?gene=A0A3Q3AZL7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A9R5", "url": "https://www.orthodb.org/?gene=A0A8V1A9R5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24412", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24412", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24412:SF497", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24412:SF497", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00651", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00651", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01344", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01344", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07707", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07707", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24681", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24681", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015136574", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015136574", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q2TVA6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TVA6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2TVA6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TVA6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q3AZL7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3AZL7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q3AZL7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3AZL7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A9R5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9R5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A9R5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9R5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLEAAAAAEPELDPEDLVHFSVGDLPSRGYGVMGEIRRQGKLCDVTLKVGDHKFSAHRIVLAASIPYFHAMFTNDMMECKQDEIVMQGMDPSALEALINFAYNGHLAIDQQNVQSLLMGASFLQLQNIKDACCTFLRERLHPKNCLGVRQFAETMMCAVLYDAANSFIHQHFVEVSMSEEFLALPFEDVLELVSRDELNVKSEEQVFEAALAWIRYERDQRELFLPELLSKIRLPLCRPQFLTDRVQQDDLVRCCHKCRDLVDEAKDYHLMPERRPHLPAFKTRPRCCTSIAGLIYAVGGLNSAGDSLNVVEVFDPIANRWEKCQPMTTARSRVGVAVVNGLLYAIGGYDGQLRLSTVEVYNPEMDSWSKVESMNSKRSAMGTVVLDGQIYVCGGYDGNSSLNSVESYSPETNKWTVVTPMSSNRSAAGVTVFEGRIYVSGGHDGLQIFNSVEYYNQHTATWHPVASMLNKRCRHGAASLGSKMFVCGGYDGSAFLSIAEVYSSVADQWYLIVPMNTRRSRVSLVANCGRLYAVGGYDGQSNLSSVEMYDPETNRWTFMAPMVCHEGGVGVGCIPLLTI", "length": 579, "header": "tr|A0A8V1A9R5-1|A0A8V1A9R5_CHICK Isoform 1 of Kelch like family member 18 OS=Gallus gallus OX=9031 GN=KLHL18 PE=1 SV=1 CANONICAL=A0A8V1A9R5-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2TVA6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9R5/entry#A0A3Q2TVA6-1", "sequence": { "sequence": "MSQVGDHKFSAHRIVLAASIPYFHAMFTNDMMECKQDEIVMQGMDPSALEALINFAYNGHLAIDQQNVQSLLMGASFLQLQNIKDACCTFLRERLHPKNCLGVRQFAETMMCAVLYDAANSFIHQHFVEVSMSEEFLALPFEDVLELVSRDELNVKSEEQVFEAALAWIRYERDQRELFLPELLSKIRLPLCRPQFLTDRVQQDDLVRCCHKCRDLVDEAKDYHLMPERRPHLPAFKTRPRCCTSIAGLIYAVGGLNSAGDSLNVVEVFDPIANRWEKCQPMTTARSRVGVAVVNGLLYAIGGYDGQLRLSTVEVYNPEMDSWSKVESMNSKRSAMGTVVLDGQIYVCGGYDGNSSLNSVESYSPETNKWTVVTPMSSNRSAAGVTVFEGRIYVSGGHDGLQIFNSVEYYNQHTATWHPVASMLNKRCRHGAASLGSKMFVCGGYDGSAFLSIAEVYSSVADQWYLIVPMNTRRSRVSLVANCGRLYAVGGYDGQSNLSSVEMYDPETNRWTFMAPMVCHEGGVGVGCIPLLTI", "length": 534, "header": "tr|A0A3Q2TVA6-1|A0A3Q2TVA6_CHICK Computationally mapped isoform of Kelch like family member 18 OS=Gallus gallus OX=9031 GN=KLHL18 PE=4 SV=1 CANONICAL=A0A8V1A9R5-1" }, "locus": { "chromosome": "2", "start_pos": 4005135, "end_pos": 3994518, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063197.1", "url": "https://www.ensembl.org/id/ENSGALT00010063197.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039010.1", "url": "https://www.ensembl.org/id/ENSGALP00010039010.1" } ] } }, { "isoform_ac": "A0A3Q3AZL7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9R5/entry#A0A3Q3AZL7-1", "sequence": { "sequence": "MIQLSLTQLESCCMTVGDHKFSAHRIVLAASIPYFHAMFTNDMMECKQDEIVMQGMDPSALEALINFAYNGHLAIDQQNVQSLLMGASFLQLQNIKDACCTFLRERLHPKNCLGVRQFAETMMCAVLYDAANSFIHQHFVEVSMSEEFLALPFEDVLELVSRDELNVKSEEQVFEAALAWIRYERDQRELFLPELLSKIRLPLCRPQFLTDRVQQDDLVRCCHKCRDLVDEAKDYHLMPERRPHLPAFKTRPRCCTSIAGLIYAVGGLNSAGDSLNVVEVFDPIANRWEKCQPMTTARSRVGVAVVNGLLYAIGGYDGQLRLSTVEVYNPEMDSWSKVESMNSKRSAMGTVVLDGQIYVCGGYDGNSSLNSVESYSPETNKWTVVTPMSSNRSAAGVTVFEGRIYVSGGHDGLQIFNSVEYYNQHTATWHPVASMLNKRCRHGAASLGSKMFVCGGYDGSAFLSIAEVYSSVADQWYLIVPMNTRRSRVSLVANCGRLYAVGGYDGQSNLSSVEMYDPETNRWTFMAPMVCHEGGVGVGCIPLLTI", "length": 546, "header": "tr|A0A3Q3AZL7-1|A0A8V1A9R5_CHICK Computationally mapped isoform of Kelch like family member 18 OS=Gallus gallus OX=9031 GN=KLHL18 PE=1 SV=1 CANONICAL=A0A8V1A9R5-1" }, "locus": { "chromosome": "2", "start_pos": 4005135, "end_pos": 3993419, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063203.1", "url": "https://www.ensembl.org/id/ENSGALT00010063203.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039014.1", "url": "https://www.ensembl.org/id/ENSGALP00010039014.1" } ] } }, { "isoform_ac": "A0A8V1A9R5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9R5/entry#A0A8V1A9R5-1", "sequence": { "sequence": "MLEAAAAAEPELDPEDLVHFSVGDLPSRGYGVMGEIRRQGKLCDVTLKVGDHKFSAHRIVLAASIPYFHAMFTNDMMECKQDEIVMQGMDPSALEALINFAYNGHLAIDQQNVQSLLMGASFLQLQNIKDACCTFLRERLHPKNCLGVRQFAETMMCAVLYDAANSFIHQHFVEVSMSEEFLALPFEDVLELVSRDELNVKSEEQVFEAALAWIRYERDQRELFLPELLSKIRLPLCRPQFLTDRVQQDDLVRCCHKCRDLVDEAKDYHLMPERRPHLPAFKTRPRCCTSIAGLIYAVGGLNSAGDSLNVVEVFDPIANRWEKCQPMTTARSRVGVAVVNGLLYAIGGYDGQLRLSTVEVYNPEMDSWSKVESMNSKRSAMGTVVLDGQIYVCGGYDGNSSLNSVESYSPETNKWTVVTPMSSNRSAAGVTVFEGRIYVSGGHDGLQIFNSVEYYNQHTATWHPVASMLNKRCRHGAASLGSKMFVCGGYDGSAFLSIAEVYSSVADQWYLIVPMNTRRSRVSLVANCGRLYAVGGYDGQSNLSSVEMYDPETNRWTFMAPMVCHEGGVGVGCIPLLTI", "length": 579, "header": "tr|A0A8V1A9R5-1|A0A8V1A9R5_CHICK Isoform 1 of Kelch like family member 18 OS=Gallus gallus OX=9031 GN=KLHL18 PE=1 SV=1 CANONICAL=A0A8V1A9R5-1" }, "locus": { "chromosome": "2", "start_pos": 4005135, "end_pos": 3985378, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063207.1", "url": "https://www.ensembl.org/id/ENSGALT00010063207.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039016.1", "url": "https://www.ensembl.org/id/ENSGALP00010039016.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9R5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9R5" } ], "pmid": "" }, { "name": "Cul3-RING ubiquitin ligase complex", "id": "GO:0031463", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031463", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9R5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9R5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9R5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9R5" } ], "pmid": "" }, { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9R5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9R5" } ], "pmid": "" }, { "name": "positive regulation of mitotic cell cycle phase transition", "id": "GO:1901992", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901992", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9R5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9R5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "ubiquitin-like ligase-substrate adaptor activity", "id": "GO:1990756", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990756", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9R5", "url": 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"enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 399, "end_pos": 401 }, { "start_pos": 424, "end_pos": 426 }, { "start_pos": 542, "end_pos": 544 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A7I1-1", "uniprot_ac": "A0A8V1A7I1", "uniprot_id": "A0A8V1A7I1_CHICK", "mass": { "chemical_mass": 92753.0, "monoisotopic_mass": 92753.0 }, "refseq": { "ac": "XP_015154814", "name": "cell division cycle protein 27 homolog isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015154814" }, "gene_names": [ { "name": "CDC27", "type": "recommended", "evidence": [ { "id": "A0A8V1A7I1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7I1" } ] }, { "name": "CDC27", "type": "synonym", "evidence": [ { "id": "XP_015154814", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015154814" } ] } ], "protein_names": [ { "name": "Cell division cycle protein 27 homolog", "type": "recommended", "evidence": [ { "id": "A0A8V1A7I1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7I1/entry#names_and_taxonomy" } ] }, { "name": "cell division cycle protein 27 homolog isoform X3", "type": "synonym", "evidence": [ { "id": "XP_015154814", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015154814" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052558.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015154814", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015154814" } ] }, { "annotation": "Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. The APC/C complex catalyzes assembly of branched 'Lys-11'-/'Lys-48'-linked branched ubiquitin chains on target proteins.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7I1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7I1#function" }, { "database": "UniProtKB", "id": "ARBA00045696", "url": "https://www.uniprot.org/uniprotkb/ARBA00045696#function" }, { "database": "UniProtKB", "id": "A0A8V0ZUS9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUS9#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7I1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7I1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CDC27", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7I1", "locus": { "chromosome": "27", "start_pos": 2520098, "end_pos": 2493191, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010024770", "url": "https://www.ensembl.org/id/ENSGALG00010024770" } ] } } ], "crossref": [ { "id": "A0A8V1A7I1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A7I1", "database": "AlphaFoldDB", "categories": [] }, { "id": "419960", "url": "https://www.ncbi.nlm.nih.gov/gene/419960", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019734", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019734", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZUR1", "url": "https://www.orthodb.org/?gene=A0A8V0ZUR1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZUS9", "url": "https://www.orthodb.org/?gene=A0A8V0ZUS9", "database": "OrthoDB", "categories": [ 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CANONICAL=A0A8V1A7I1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZUR1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7I1/entry#A0A8V0ZUR1-1", "sequence": { "sequence": 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"MTVLQEPVQAAIWQALNHYAYRDAVFLAERLYAEVHSEEALFLLATCYYRSGKAYKAYRLLKGHSCTTPQCKYLLAKCCVDLSKLAEGEQILSGGVLNKQKSHDDIVTEFGDSACFTLSLLGHVYCKTDRLAKGSECYQKSLSLNPFLWSPFESLCEIGEKPDPDQTFKLTSLQNFSSCLPNTCTTLVSNHNISHRQPETVLMETPQDTIELNRINLESSNAKYSSLNTDSSMSYIDSAVISPDAVPLGSGTAILSKQAQNKPKTGRSLLGGPAALSPLTPSFGILPLETPSPGDGSYLQNYTNSTSVIDVPSTGAPSKKAVTRISQAGTKSVFSQSGNSREVTPILVAQTQSSGPQTSTTPQVLSPTIAAPPNSLPRRSSRLFTSDSSTTKENSKKLKMKFPPKIANRKTKSKTNKGGITQPNINDSLEITKLDSSIISEGKISTVAPQIQAFTLQKAAAEGLMSLLRDMGKGYLALCSYNCKEAINILSHLPSHHYNTGWVLCQIGRAYFELAEYMQAERIFSEVRRIENYRVEGMEIYSTTLWHLQKDVALSVLSKDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAINIDPKNPLCKFHRASVLFANEKYKSALQELEELKQIVPKESLVYFLIGKVYKKLGQTHLALMNFSWAMDLDPKGANNQIKEAIDKRYLPDDEEPITQEEQISECYPYESVHLVG", "length": 812, "header": "tr|A0A8V0ZUS9-1|A0A8V1A7I1_CHICK Computationally mapped isoform of Cell division cycle protein 27 homolog OS=Gallus gallus OX=9031 GN=CDC27 PE=3 SV=1 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CANONICAL=A0A8V1A7I1-1" }, "locus": { "chromosome": "27", "start_pos": 2518787, "end_pos": 2493537, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010060556.1", "url": "https://www.ensembl.org/id/ENSGALT00010060556.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010037315.1", "url": "https://www.ensembl.org/id/ENSGALP00010037315.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-141430", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-141430", "resource": "Reactome", "description": "Inactivation of APC/C via direct inhibition of the APC/C complex" }, { "id": "R-GGA-174048", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-174048", "resource": "Reactome", "description": "APC/C:Cdc20 mediated degradation of Cyclin B" }, { "id": "R-GGA-174084", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-174084", "resource": "Reactome", "description": "Autodegradation of Cdh1 by Cdh1:APC/C" }, { "id": "R-GGA-174154", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-174154", "resource": "Reactome", "description": "APC/C:Cdc20 mediated degradation of Securin" }, { "id": "R-GGA-174178", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-174178", "resource": "Reactome", "description": "APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1" }, { "id": "R-GGA-174184", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-174184", "resource": "Reactome", "description": "Cdc20:Phospho-APC/C mediated degradation of Cyclin A" }, { "id": "R-GGA-176407", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-176407", "resource": "Reactome", "description": "Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase" }, { "id": "R-GGA-176408", "name": "", "url": 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"resource": "Reactome", "description": "Senescence-Associated Secretory Phenotype (SASP)" }, { "id": "R-GGA-68867", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-68867", "resource": "Reactome", "description": "Assembly of the pre-replicative complex" }, { "id": "R-GGA-69017", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-69017", "resource": "Reactome", "description": "CDK-mediated phosphorylation and removal of Cdc6" }, { "id": "R-GGA-983168", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983168", "resource": "Reactome", "description": "Antigen processing: Ubiquitination & Proteasome degradation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7I1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7I1" } ], "pmid": "" }, { "name": "spindle", "id": "GO:0005819", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005819", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7I1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7I1" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7I1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7I1" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7I1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7I1" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7I1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7I1" } ], "pmid": "" }, { "name": "anaphase-promoting complex", "id": 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"table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A801-1", "uniprot_ac": "A0A8V1A801", "uniprot_id": "A0A8V1A801_CHICK", "mass": { "chemical_mass": 24667.0, "monoisotopic_mass": 24667.0 }, "refseq": {}, "gene_names": [ { "name": "TPD52L2", "type": "recommended", "evidence": [ { "id": "A0A8V1A801", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A801" } ] } ], "protein_names": [ { "name": "Tumor protein D52 like 2", "type": "synonym", "evidence": [ { "id": "A0A8V1A801", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A801/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A801", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A801" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TPD52L2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A801", "locus": { "chromosome": "20", "start_pos": 9878328, "end_pos": 9894470, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010024870", "url": "https://www.ensembl.org/id/ENSGALG00010024870" } ] } } ], "crossref": [ { "id": "A0A8V1A801", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A801", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000004683", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000004683", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR007327", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007327", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5NXQ7", "url": 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"https://www.orthodb.org/?gene=A0A8V1A801", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19307", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19307", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19307:SF13", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19307:SF13", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04201", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04201", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A1D5NXQ7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NXQ7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5NXQ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NXQ7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZVB1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVB1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZVB1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVB1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZVB6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVB6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZVB6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVB6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A0G8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0G8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A0G8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0G8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A2Q1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2Q1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A2Q1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2Q1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A2R6", "url": 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"MESASQDISLNSPNKGLLSDAMMDVPVDSAAAARTATPEGLSAAEEEELRAEIAKVEEEIGTLRQVLAAKERHCGELKRKLGLTPLDGLKQNLSKSWHDVQVSNAYLSASSTLEDWNEKLTQSEAYKKTQETLSQAGQKTSAALSNVGSVISRKLGDMRAHPFSHSFSSYSIRHSISMPAMRNSATFKSFEDRVGTIKSRVVGSRENSTEGLQSPSAGDKPPQDNAPF", "length": 228, "header": "tr|A0A8V1A801-1|A0A8V1A801_CHICK Isoform 1 of Tumor protein D52 like 2 OS=Gallus gallus OX=9031 GN=TPD52L2 PE=1 SV=1 CANONICAL=A0A8V1A801-1" }, "isoforms": [ { "isoform_ac": "A0A1D5NXQ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A801/entry#A0A1D5NXQ7-1", "sequence": { "sequence": "MESASQDISLNSPNKGLLSDAMMDVPVDSAAAARTATPEGLSAAEEEELRAEIAKVEEEIGTLRQVLAAKERHCGELKRKLGLTPLDGLKQNLSKSWHDVQVSNAYVRTSEKLGEWNDKVTQSDLYLSASSTLEDWNEKLTQSEAYKKTQETLSQAGQKTSAALSNVGSVISRKLGDMRNSATFKSFEDRVGTIKSRVVGSRENSTEGLQSPSAGDKPPQDNAPF", "length": 225, "header": "tr|A0A1D5NXQ7-1|A0A1D5NXQ7_CHICK Computationally mapped isoform of Tumor protein D52 like 2 OS=Gallus gallus OX=9031 GN=TPD52L2 PE=1 SV=2 CANONICAL=A0A8V1A801-1" }, "locus": { "chromosome": "20", "start_pos": 9894417, "end_pos": 9880035, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010060727.1", "url": "https://www.ensembl.org/id/ENSGALT00010060727.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010037486.1", "url": "https://www.ensembl.org/id/ENSGALP00010037486.1" } ] } }, { "isoform_ac": "A0A8V0ZVB1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A801/entry#A0A8V0ZVB1-1", "sequence": { "sequence": "MESASQDISLNSPNKGLLSDAMMDVPVDSAAAARTATPEGLSAAEEEELRAEIAKVEEEIGTLRQVLAAKERHCGELKRKLGLTPLDGLKQNLSKSWHDVQVSNAYVRTSEKLGEWNDKVTQSDLYLSASSTLEDWNEKLTQSEAYKKTQETLSQAGQKTSAALSNVGSVISRKLGDMRAHPFSHSFSSYSIRHSISMPAMRNSATFKSFEDRVGTIKSRVVGSRENSTEGLQSPSAGDKPPQDNAPF", "length": 248, "header": "tr|A0A8V0ZVB1-1|A0A8V1A801_CHICK Computationally mapped isoform of Tumor protein D52 like 2 OS=Gallus gallus OX=9031 GN=TPD52L2 PE=1 SV=1 CANONICAL=A0A8V1A801-1" }, "locus": { "chromosome": "20", "start_pos": 9894417, "end_pos": 9880035, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010060733.1", "url": "https://www.ensembl.org/id/ENSGALT00010060733.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010037492.1", "url": "https://www.ensembl.org/id/ENSGALP00010037492.1" } ] } }, { "isoform_ac": "A0A8V0ZVB6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A801/entry#A0A8V0ZVB6-1", "sequence": { "sequence": "MESASQDISLNSPNKGLLSDAMMDVPVDSAAAARTATPEGLSAAEEEELRAEIAKVEEEIGTLRQVLAAKERHCGELKRKLGLTPLDGLKQNLSKSWHDVQVSNAYVRTSEKLGEWNDKVTQSDFYKKTQETLSQAGQKTSAALSNVGSVISRKLGDMRAHPFSHSFRNSATFKSFEDRVGTIKSRVVGSRENSTEGLQSPSAGDKPPQDNAPF", "length": 214, "header": "tr|A0A8V0ZVB6-1|A0A8V1A801_CHICK Computationally mapped isoform of Tumor protein D52 like 2 OS=Gallus gallus OX=9031 GN=TPD52L2 PE=1 SV=1 CANONICAL=A0A8V1A801-1" }, "locus": { "chromosome": "20", "start_pos": 9894417, "end_pos": 9880035, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010060738.1", "url": "https://www.ensembl.org/id/ENSGALT00010060738.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010037497.1", "url": "https://www.ensembl.org/id/ENSGALP00010037497.1" } ] } }, { "isoform_ac": "A0A8V1A0G8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A801/entry#A0A8V1A0G8-1", "sequence": { "sequence": "MESASQDISLNSPNKGLLSDAMMDVPVDSAAAARTATPEGLSAAEEEELRAEIAKVEEEIGTLRQVLAAKERHCGELKRKLGLTPLDGLKQNLSKSWHDVQVSNAYVRTSEKLGEWNDKVTQSDFYKKTQETLSQAGQKTSAALSNVGSVISRKLGDMSSYSIRHSISMPAMRNSATFKSFEDRVGTIKSRVVGSRENSTEGLQSPSAGDKPPQDNAPF", "length": 219, "header": "tr|A0A8V1A0G8-1|A0A8V1A801_CHICK Computationally mapped isoform of Tumor protein D52 like 2 OS=Gallus gallus OX=9031 GN=TPD52L2 PE=1 SV=1 CANONICAL=A0A8V1A801-1" }, "locus": { "chromosome": "20", "start_pos": 9894417, "end_pos": 9880035, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010060740.1", "url": "https://www.ensembl.org/id/ENSGALT00010060740.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010037499.1", "url": "https://www.ensembl.org/id/ENSGALP00010037499.1" } ] } }, { "isoform_ac": "A0A8V1A2Q1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A801/entry#A0A8V1A2Q1-1", "sequence": { "sequence": "MESASQDISLNSPNKGLLSDAMMDVPVDSAAAARTATPEGLSAAEEEELRAEIAKVEEEIGTLRQVLAAKERHCGELKRKLGLTPLDGLKQNLSKSWHDVQVSNAYVRTSEKLGEWNDKVTQSDFYKKTQETLSQAGQKTSAALSNVGSVISRKLGDMREFPIPLWLGLPKWNSATFKSFEDRVGTIKSRVVGSRENSTEGLQSPSAGDKPPQDNAPF", "length": 218, "header": "tr|A0A8V1A2Q1-1|A0A8V1A801_CHICK Computationally mapped isoform of Tumor protein D52 like 2 OS=Gallus gallus OX=9031 GN=TPD52L2 PE=1 SV=1 CANONICAL=A0A8V1A801-1" }, "locus": { "chromosome": "20", "start_pos": 9894417, "end_pos": 9880035, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010060722.1", "url": "https://www.ensembl.org/id/ENSGALT00010060722.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010037481.1", "url": "https://www.ensembl.org/id/ENSGALP00010037481.1" } ] } }, { "isoform_ac": "A0A8V1A2R6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A801/entry#A0A8V1A2R6-1", "sequence": { "sequence": "MESASQDISLNSPNKGLLSDAMMDVPVDSAAAARTATPEGLSAAEEEELRAEIAKVEEEIGTLRQVLAAKERHCGELKRKLGLTPLDGLKQNLSKSWHDVQVSNAYVRTSEKLGEWNDKVTQSDLYLSASSTLEDWNEKLTQSEAYKKTQETLSQAGQKTSAALSNVGSVISRKLGDMSSYSIRHSISMPAMRNSATFKSFEDRVGTIKSRVVGSRENSTEGLQSPSAGDKPPQDNAPF", "length": 239, "header": "tr|A0A8V1A2R6-1|A0A8V1A801_CHICK Computationally mapped isoform of Tumor protein D52 like 2 OS=Gallus gallus OX=9031 GN=TPD52L2 PE=1 SV=1 CANONICAL=A0A8V1A801-1" }, "locus": { "chromosome": "20", "start_pos": 9894417, "end_pos": 9880035, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010060737.1", "url": "https://www.ensembl.org/id/ENSGALT00010060737.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010037496.1", "url": "https://www.ensembl.org/id/ENSGALP00010037496.1" } ] } }, { "isoform_ac": "A0A8V1A7Z1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A801/entry#A0A8V1A7Z1-1", "sequence": { "sequence": "MESASQDISLNSPNKGLLSDAMMDVPVDSAAAARTATPEGLSAAEEEELRAEIAKVEEEIGTLRQVLAAKERHCGELKRKLGLTPLDGLKQNLSKSWHDVQVSNAYKKTQETLSQAGQKTSAALSNVGSVISRKLGDMREFPIPLWLGLPKWAHPFSHSFSSYSIRHSISMPAMRNSATFKSFEDRVGTIKSRVVGSRENSTEGLQSPSAGDKPPQDNAPF", "length": 221, "header": "tr|A0A8V1A7Z1-1|A0A8V1A7Z1_CHICK Computationally mapped isoform of Tumor protein D52 like 2 OS=Gallus gallus OX=9031 GN=TPD52L2 PE=1 SV=1 CANONICAL=A0A8V1A801-1" }, "locus": { "chromosome": "20", "start_pos": 9894417, "end_pos": 9880035, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010060724.1", "url": "https://www.ensembl.org/id/ENSGALT00010060724.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010037483.1", "url": "https://www.ensembl.org/id/ENSGALP00010037483.1" } ] } }, { "isoform_ac": "A0A8V1A801-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A801/entry#A0A8V1A801-1", "sequence": { "sequence": "MESASQDISLNSPNKGLLSDAMMDVPVDSAAAARTATPEGLSAAEEEELRAEIAKVEEEIGTLRQVLAAKERHCGELKRKLGLTPLDGLKQNLSKSWHDVQVSNAYLSASSTLEDWNEKLTQSEAYKKTQETLSQAGQKTSAALSNVGSVISRKLGDMRAHPFSHSFSSYSIRHSISMPAMRNSATFKSFEDRVGTIKSRVVGSRENSTEGLQSPSAGDKPPQDNAPF", "length": 228, "header": "tr|A0A8V1A801-1|A0A8V1A801_CHICK Isoform 1 of Tumor protein D52 like 2 OS=Gallus gallus OX=9031 GN=TPD52L2 PE=1 SV=1 CANONICAL=A0A8V1A801-1" }, "locus": { "chromosome": "20", "start_pos": 9894417, "end_pos": 9880035, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010060734.1", "url": "https://www.ensembl.org/id/ENSGALT00010060734.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010037493.1", "url": "https://www.ensembl.org/id/ENSGALP00010037493.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A801", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A801" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 207, "end_pos": 209, "annotation": "n_glycosylation_sequon" }, { "start_pos": 92, "end_pos": 94, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 207, "end_pos": 209 }, { "start_pos": 92, "end_pos": 94 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A8I5-1", "uniprot_ac": "A0A8V1A8I5", "uniprot_id": "A0A8V1A8I5_CHICK", "mass": { "chemical_mass": 28670.0, "monoisotopic_mass": 28670.0 }, "refseq": {}, "gene_names": [ { "name": "RABL3", "type": "recommended", "evidence": [ { "id": "A0A8V1A8I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8I5" } ] } ], "protein_names": [ { "name": "Rab-like protein 3", "type": "recommended", "evidence": [ { "id": "A0A8V1A8I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8I5/entry#names_and_taxonomy" } ] }, { "name": "3.6.5.2", "type": "synonym", "evidence": [ { "id": "A0A8V1A8I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8I5/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Small GTPase required for KRAS signaling regulation and modulation of cell proliferation. Regulator of KRAS prenylation, and probably prenylation of other small GTPases. Required for lymphocyte development and function. Not required for myeloid cell development. Interacts with Rab11 to promote ciliary vesicle formation at the mother centriole, thereby regulating early ciliogenesis. The GTP-binding capacity of RABL3 is essential for ciliogenesis.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A111", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A111#function" }, { "database": "UniProtKB", "id": "ARBA00094278", "url": "https://www.uniprot.org/uniprotkb/ARBA00094278#function" }, { "database": "UniProtKB", "id": "A0A8V1A8I5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8I5#function" }, { "database": "UniProtKB", "id": "A0A8V0ZVU0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVU0#function" }, { "database": "UniProtKB", "id": "A0A8V0ZVU5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVU5#function" }, { "database": "UniProtKB", "id": "A0A8V0ZVU9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVU9#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A8I5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8I5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RABL3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8I5", "locus": { "chromosome": "1", "start_pos": 79839779, "end_pos": 79823943, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010024940", "url": "https://www.ensembl.org/id/ENSGALG00010024940" } ] } } ], "crossref": [ { "id": "A0A8V1A8I5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A8I5", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd04102", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04102", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR025662", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025662", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZVU0", "url": "https://www.orthodb.org/?gene=A0A8V0ZVU0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZVU5", "url": "https://www.orthodb.org/?gene=A0A8V0ZVU5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZVU9", "url": "https://www.orthodb.org/?gene=A0A8V0ZVU9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A111", "url": "https://www.orthodb.org/?gene=A0A8V1A111", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A8I5", "url": "https://www.orthodb.org/?gene=A0A8V1A8I5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24073", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24073", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08477", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08477", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "19669", "url": "https://www.rhea-db.org/rhea/19669", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZVU0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVU0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZVU0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVU0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZVU5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVU5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZVU5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVU5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZVU9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVU9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZVU9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVU9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A111", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A111", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A111-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A111-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A8I5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8I5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A8I5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8I5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAALDRVKVLVLGDSGVGKSSLVHLLCHNQVLGNPSWTVGCSVDVRIHDYKEGTPEEKTYYIELWDVGGSVGSATSVKSTRAVFYNSLNGIILVHDLTNKKSSQNLYRWSLEALNRDVAPTGVLVTNGDYDREQFADNQIPLLVIGTKLDQIPETKRNEVLTRTAFLAEDFNAEEINLDCTNPRYLAAGSSNAVKLSRFFDKTGGGGCIGALQHGQFVYHPQRTSDREEVLLKRWQSDSWLLGKKEIWRRNTEEPSL", "length": 257, "header": "tr|A0A8V1A8I5-1|A0A8V1A8I5_CHICK Isoform 1 of Rab-like protein 3 OS=Gallus gallus OX=9031 GN=RABL3 PE=3 SV=1 CANONICAL=A0A8V1A8I5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZVU0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8I5/entry#A0A8V0ZVU0-1", "sequence": { "sequence": "MAALDRVKVLVLGDSGVGKSSLVHLLCHNQVLGNPSWTVGCSVDVRIHDYKEGTPEEKTYYIELWDVGGSVGSATSVKSTRAVFYNSLNGIILVHDLTNKKSSQNLYRWSLEALNRDVAPTGVLVTNGDYDREQFADNQIPLLVIGTKLDQIPETKRNEVLTRTAFLAEDFNAEEINLDCTNPRYLAAGSSNAVKLSRFFDKVIKSNFRNEEI", "length": 213, "header": "tr|A0A8V0ZVU0-1|A0A8V1A8I5_CHICK Computationally mapped isoform of Rab-like protein 3 OS=Gallus gallus OX=9031 GN=RABL3 PE=3 SV=1 CANONICAL=A0A8V1A8I5-1" }, "locus": { "chromosome": "1", "start_pos": 79834430, "end_pos": 79826918, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010060916.1", "url": "https://www.ensembl.org/id/ENSGALT00010060916.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010037673.1", "url": "https://www.ensembl.org/id/ENSGALP00010037673.1" } ] } }, { "isoform_ac": "A0A8V0ZVU5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8I5/entry#A0A8V0ZVU5-1", "sequence": { "sequence": "MAALDRVKVLVLGDSGVGKSSLVHLLCHNQVLGNPSWTVGCSVDVRIHDYKEGTPEEKTYYIELWDVGGSVGSATSVKSTRAVFYNSLNEMGRWLSCLFLLLLSLGIILVHDLTNKKSSQNLYRWSLEALNRDVAPTGVLVTNGDYDREQFADNQIPLLVIGTKLDQIPETKRNEVLTRTAFLAEDFNAEEINLDCTNPRYLAAGSSNAVKLSRFFDKVIEKRYFLRDGNQIPGFSERKRFGGGTLKSLHYD", "length": 252, "header": "tr|A0A8V0ZVU5-1|A0A8V1A8I5_CHICK Computationally mapped isoform of Rab-like protein 3 OS=Gallus gallus OX=9031 GN=RABL3 PE=3 SV=1 CANONICAL=A0A8V1A8I5-1" }, "locus": { "chromosome": "1", "start_pos": 79837275, "end_pos": 79826918, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010060921.1", "url": "https://www.ensembl.org/id/ENSGALT00010060921.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010037678.1", "url": "https://www.ensembl.org/id/ENSGALP00010037678.1" } ] } }, { "isoform_ac": "A0A8V0ZVU9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8I5/entry#A0A8V0ZVU9-1", "sequence": { "sequence": "MAALDRVKVLVLGDSGVGKSSLVHLLCHNQVLGNPSWTVGCSIHDYKEGTPEEKTYYIELWDVGGSVGSATSVKSTRAVFYNSLNGIILVHDLTNKKSSQNLYRWSLEALNRDVAPTGVLVTNGDYDREQFADNQIPLLVIGTKLDQIPETKRNEVLTRTAFLAEDFNAEEINLDCTNPRYLAAGSSNAVKLSRFFDKVIEKRYFLRDGNQIPGFSERKRFGGGTLKSLHYD", "length": 232, "header": "tr|A0A8V0ZVU9-1|A0A8V1A8I5_CHICK Computationally mapped isoform of Rab-like protein 3 OS=Gallus gallus OX=9031 GN=RABL3 PE=3 SV=1 CANONICAL=A0A8V1A8I5-1" }, "locus": { "chromosome": "1", "start_pos": 79837275, "end_pos": 79826918, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010060926.1", "url": "https://www.ensembl.org/id/ENSGALT00010060926.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010037683.1", "url": "https://www.ensembl.org/id/ENSGALP00010037683.1" } ] } }, { "isoform_ac": "A0A8V1A111-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8I5/entry#A0A8V1A111-1", "sequence": { "sequence": "HPKGSSVGKSSLVHLLCHNQVLGNPSWTVGCSVDVRIHDYKEGTPEEKTYYIELWDVGGSVGSATSVKSTRAVFYNSLNGIILVHDLTNKKSSQNLYRWSLEALNRDVAPTGVLVTNGDYDREQFADNQIPLLVIGTKLDQIPETKRNEVLTRTAFLAEDFNAEEINLDCTNPRYLAAGSSNAVKLSRFFDKVIEKRYFLRDGNQIPGFSERKRFGGGTLKSLHYD", "length": 226, "header": "tr|A0A8V1A111-1|A0A8V1A8I5_CHICK Computationally mapped isoform of Rab-like protein 3 OS=Gallus gallus OX=9031 GN=RABL3 PE=3 SV=1 CANONICAL=A0A8V1A8I5-1" }, "locus": { "chromosome": "1", "start_pos": 79837275, "end_pos": 79825582, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010060928.1", "url": "https://www.ensembl.org/id/ENSGALT00010060928.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010037685.1", "url": "https://www.ensembl.org/id/ENSGALP00010037685.1" } ] } }, { "isoform_ac": "A0A8V1A8I5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8I5/entry#A0A8V1A8I5-1", "sequence": { "sequence": "MAALDRVKVLVLGDSGVGKSSLVHLLCHNQVLGNPSWTVGCSVDVRIHDYKEGTPEEKTYYIELWDVGGSVGSATSVKSTRAVFYNSLNGIILVHDLTNKKSSQNLYRWSLEALNRDVAPTGVLVTNGDYDREQFADNQIPLLVIGTKLDQIPETKRNEVLTRTAFLAEDFNAEEINLDCTNPRYLAAGSSNAVKLSRFFDKTGGGGCIGALQHGQFVYHPQRTSDREEVLLKRWQSDSWLLGKKEIWRRNTEEPSL", "length": 257, "header": "tr|A0A8V1A8I5-1|A0A8V1A8I5_CHICK Isoform 1 of Rab-like protein 3 OS=Gallus gallus OX=9031 GN=RABL3 PE=3 SV=1 CANONICAL=A0A8V1A8I5-1" }, "locus": { "chromosome": "1", "start_pos": 79837271, "end_pos": 79826918, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010060917.1", "url": "https://www.ensembl.org/id/ENSGALT00010060917.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010037674.1", "url": "https://www.ensembl.org/id/ENSGALP00010037674.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A8I5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8I5" } ], "pmid": "" }, { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A8I5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8I5" } ], "pmid": "" }, { "name": "G protein activity", "id": "GO:0003925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003925", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A8I5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8I5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "natural killer cell differentiation", "id": "GO:0001779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001779", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A8I5", 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} ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9C2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9C2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "HSPB2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9C2", "locus": { "chromosome": "24", "start_pos": 6264931, "end_pos": 6267832, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010025210", "url": "https://www.ensembl.org/id/ENSGALG00010025210" } ] } } ], "crossref": [ { "id": "A0A8V1A9C2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A9C2", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd06476", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06476", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001436", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001436", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002068", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002068", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003090", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003090", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008978", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008978", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZWM9", "url": "https://www.orthodb.org/?gene=A0A8V0ZWM9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A9C2", "url": "https://www.orthodb.org/?gene=A0A8V1A9C2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45640", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45640", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45640:SF27", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45640:SF27", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00011", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00011", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00525", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00525", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZWM9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWM9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZWM9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWM9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A9C2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9C2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A9C2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9C2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTLHVCTQPDQAPATIRHCPVPLGWQGQCWGPCSCLLSPAQGGEPGGAGLHPAGRQSLQLYRNAMRSFPRHPGEAAQGLCARLFWSVFLSHTPPCGIHPTKTLQSAAFTLRGSERLYRLAMAARTVPHAYPMSSEYEFANPSKIYDQNFGEGVSPCEILAPALYHGYYIRPRINKQLDRGTSEVSLNDHKYQVFLDVCHFLPDELTVRTVDNLLEVVGQHPQRADRHGFISREFTRTYILPLDVDPLLMRATLSHDGILSIVAPRTGKEVKARIIEVKIIQEQTVGQKELSEEGKGKEES", "length": 300, "header": "tr|A0A8V1A9C2-1|A0A8V1A9C2_CHICK Isoform 1 of Heat shock protein family B (small) member 2 OS=Gallus gallus OX=9031 GN=HSPB2 PE=3 SV=1 CANONICAL=A0A8V1A9C2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZWM9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9C2/entry#A0A8V0ZWM9-1", "sequence": { "sequence": "YCSCTCSAARSKALPPHAPHLTHTPQRLGLCRTYPSAHLHCQQRLHPACGRGVSPCEILAPALYHGYYIRPRINKQLDRGTSEVSLNDHKYQVFLDVCHFLPDELTVRTVDNLLEVVGQHPQRADRHGFISREFTRTYILPLDVDPLLMRATLSHDGILSIVAPRTGKEVKARIIEVKIIQEQTVGQKELSEEGKGKEES", "length": 200, "header": "tr|A0A8V0ZWM9-1|A0A8V1A9C2_CHICK Computationally mapped isoform of Heat shock protein family B (small) member 2 OS=Gallus gallus OX=9031 GN=HSPB2 PE=3 SV=1 CANONICAL=A0A8V1A9C2-1" }, "locus": { "chromosome": "24", "start_pos": 6267090, "end_pos": 6265883, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010061499.1", "url": "https://www.ensembl.org/id/ENSGALT00010061499.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010037992.1", "url": "https://www.ensembl.org/id/ENSGALP00010037992.1" } ] } }, { "isoform_ac": "A0A8V1A9C2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9C2/entry#A0A8V1A9C2-1", "sequence": { "sequence": "MTLHVCTQPDQAPATIRHCPVPLGWQGQCWGPCSCLLSPAQGGEPGGAGLHPAGRQSLQLYRNAMRSFPRHPGEAAQGLCARLFWSVFLSHTPPCGIHPTKTLQSAAFTLRGSERLYRLAMAARTVPHAYPMSSEYEFANPSKIYDQNFGEGVSPCEILAPALYHGYYIRPRINKQLDRGTSEVSLNDHKYQVFLDVCHFLPDELTVRTVDNLLEVVGQHPQRADRHGFISREFTRTYILPLDVDPLLMRATLSHDGILSIVAPRTGKEVKARIIEVKIIQEQTVGQKELSEEGKGKEES", "length": 300, "header": "tr|A0A8V1A9C2-1|A0A8V1A9C2_CHICK Isoform 1 of Heat shock protein family B (small) member 2 OS=Gallus gallus OX=9031 GN=HSPB2 PE=3 SV=1 CANONICAL=A0A8V1A9C2-1" }, "locus": { "chromosome": "24", "start_pos": 6267772, "end_pos": 6265883, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010061494.1", "url": "https://www.ensembl.org/id/ENSGALT00010061494.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010037988.1", "url": "https://www.ensembl.org/id/ENSGALP00010037988.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9C2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9C2" } ], "pmid": "" }, { "name": 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"https://www.uniprot.org/uniprotkb/A0A8V1A9C2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "unfolded protein binding", "id": "GO:0051082", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051082", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9C2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9C2" } ], "pmid": "" }, { "name": "structural constituent of eye lens", "id": "GO:0005212", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005212", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9C2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9C2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1A9C2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9C2" }, { "id": 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"count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A715-1", "uniprot_ac": "A0A8V1A715", "uniprot_id": "A0A8V1A715_CHICK", "mass": { "chemical_mass": 46459.0, "monoisotopic_mass": 46459.0 }, "refseq": { "ac": "XP_417876", "name": "junctional adhesion molecule C isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417876" }, "gene_names": [ { "name": "JAM3", "type": "recommended", "evidence": [ { "id": "A0A8V1A715", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A715" } ] }, { "name": "JAM3", "type": "synonym", "evidence": [ { "id": "XP_417876", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417876" } ] } ], "protein_names": [ { "name": "Junctional adhesion molecule 3", "type": "synonym", "evidence": [ { "id": "A0A8V1A715", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A715/entry#names_and_taxonomy" } ] }, { "name": "junctional adhesion molecule C isoform X1", "type": "synonym", "evidence": [ { "id": "XP_417876", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417876" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052555.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_417876.4. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_417876", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417876" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A715", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A715" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "JAM3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A715", "locus": { "chromosome": "24", "start_pos": 2573542, "end_pos": 2546412, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010025320", "url": "https://www.ensembl.org/id/ENSGALG00010025320" } ] } } ], "crossref": [ { "id": "A0A8V1A715", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A715", "database": "AlphaFoldDB", "categories": [] }, { "id": "419736", "url": 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"id": "IPR042974", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042974", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ELSCIIM", "url": "https://omabrowser.org/oma/group/ELSCIIM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZX45", "url": "https://www.orthodb.org/?gene=A0A8V0ZX45", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A2D2", "url": "https://www.orthodb.org/?gene=A0A8V1A2D2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A4N9", "url": "https://www.orthodb.org/?gene=A0A8V1A4N9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A715", "url": "https://www.orthodb.org/?gene=A0A8V1A715", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A9T6", "url": "https://www.orthodb.org/?gene=A0A8V1A9T6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A9U2", "url": "https://www.orthodb.org/?gene=A0A8V1A9U2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR44598", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44598", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR44598:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44598:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07686", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07686", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13927", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13927", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-202733", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-202733", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-216083", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-216083", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_417876", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417876", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZX45", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZX45", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZX45-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZX45-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A2D2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2D2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A2D2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2D2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A4N9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4N9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A4N9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4N9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A715", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A715", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A715-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A715-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A9T6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9T6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A9T6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9T6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A9U2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9U2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A9U2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9U2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MIWRDLSLAGWQAVLSTLPWLQCAICPPPGCRGGEAEAAFKCPLSVLQLGARPGERFWQHLIQGADVRGKNTLIHKTPSLGFAREPQRLSARGREHVHEVKRGALGSWDSCWDWRDFLKVLIGRTSLRAASVGCSGCRLLAVELTSSNTKPVVQEFQSVELSCIIKSTVTPDPRIEWKKIRDGETSYVFFDNKMQGDFATRAEILSRTSLVIKNTTRMDTATYRCEVAAPSDTKTIDEINIQLTVQVKPVTPRCTVPKAVPVGKTASLHCHENEGFPKSTYSWYRNSEPLSPDTKSNAKFQNSSYSLNPTTGTLVFHAVHKGDTGRYSCIATNDAGFAKCEEQEMEVYDLNIGGIIGGVLVVVAVLVLITLGICCAYRRGYFANSKENGESYKTPAKPDGVNYIRTDDEGDFRHKSSFVI", "length": 420, "header": "tr|A0A8V1A715-1|A0A8V1A715_CHICK Isoform 1 of Junctional adhesion molecule 3 OS=Gallus gallus OX=9031 GN=JAM3 PE=1 SV=1 CANONICAL=A0A8V1A715-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZX45-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A715/entry#A0A8V0ZX45-1", "sequence": { "sequence": "MHGECQDIPGSSACRPQSLQDGGTGLSRGQEQQTLQCWAGTRAPDQHSAGSIRLRKCSAKNSSEICLRRKTSQGLGEVSSRICGSFSSPRTGSLLTSPCRGCRLLAVELTSSNTKPVVQEFQSVELSCIIKSTVTPDPRIEWKKIRDGETSYVFFDNKMQGDFATRAEILSRTSLVIKNTTRMDTATYRCEVAAPSDTKTIDEINIQLTVQVKPVTPRCTVPKAVPVGKTASLHCHENEGFPKSTYSWYRNSEPLSPDTKSNAKFQNSSYSLNPTTGTLVFHAVHKGDTGRYSCIATNDAGFAKCEEQEMEVYDLNIGGIIGGVLVVVAVLVLITLGICCAYRRGYFANSKENGESYKTPAKPDGVNYIRTDDEGDFRHKSSFVI", "length": 385, "header": "tr|A0A8V0ZX45-1|A0A8V1A715_CHICK Computationally mapped isoform of Junctional adhesion molecule 3 OS=Gallus gallus OX=9031 GN=JAM3 PE=1 SV=1 CANONICAL=A0A8V1A715-1" }, "locus": { "chromosome": "24", "start_pos": 2571090, "end_pos": 2558529, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010061800.1", "url": "https://www.ensembl.org/id/ENSGALT00010061800.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038147.1", "url": "https://www.ensembl.org/id/ENSGALP00010038147.1" } ] } }, { "isoform_ac": "A0A8V1A2D2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A715/entry#A0A8V1A2D2-1", "sequence": { "sequence": "MLSELEVYLFRQLWHVAHDASSWHSGFARQVVPKSDGCRLLAVELTSSNTKPVVQEFQSVELSCIIKSTVTPDPRIEWKKIRDGETSYVFFDNKMQGDFATRAEILSRTSLVIKNTTRMDTATYRCEVAAPSDTKTIDEINIQLTVQVKPVTPRCTVPKAVPVGKTASLHCHENEGFPKSTYSWYRNSEPLSPDTKSNAKFQNSSYSLNPTTGTLVFHAVHKGDTGRYSCIATNDAGFAKCEEQEMEVYDLNIGGIIGGVLVVVAVLVLITLGICCAYRRGYFANSKENGESYKTPAKPDGVNYIRTDDEGDFRHKSSFVI", "length": 321, "header": "tr|A0A8V1A2D2-1|A0A8V1A715_CHICK Computationally mapped isoform of Junctional adhesion molecule 3 OS=Gallus gallus OX=9031 GN=JAM3 PE=1 SV=1 CANONICAL=A0A8V1A715-1" }, "locus": { "chromosome": "24", "start_pos": 2571090, "end_pos": 2560742, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010061811.1", "url": "https://www.ensembl.org/id/ENSGALT00010061811.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038155.1", "url": "https://www.ensembl.org/id/ENSGALP00010038155.1" } ] } }, { "isoform_ac": "A0A8V1A4N9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A715/entry#A0A8V1A4N9-1", "sequence": { "sequence": "MAECVRSLTAPPGHAHCCSRAAAHHTSTRGFGTCLSPRPGRGCCSQGCVWLMELCGWSLGAVGHTRPGNTGCRLLAVELTSSNTKPVVQEFQSVELSCIIKSTVTPDPRIEWKKIRDGETSYVFFDNKMQGDFATRAEILSRTSLVIKNTTRMDTATYRCEVAAPSDTKTIDEINIQLTVQVKPVTPRCTVPKAVPVGKTASLHCHENEGFPKSTYSWYRNSEPLSPDTKSNAKFQNSSYSLNPTTGTLVFHAVHKGDTGRYSCIATNDAGFAKCEEQEMEVYDLNIGGIIGGVLVVVAVLVLITLGICCAYRRGYFANSKENGESYKTPAKPDGVNYIRTDDEGDFRHKSSFVI", "length": 355, "header": "tr|A0A8V1A4N9-1|A0A8V1A715_CHICK Computationally mapped isoform of Junctional adhesion molecule 3 OS=Gallus gallus OX=9031 GN=JAM3 PE=1 SV=1 CANONICAL=A0A8V1A715-1" }, "locus": { "chromosome": "24", "start_pos": 2571090, "end_pos": 2555234, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010061807.1", "url": "https://www.ensembl.org/id/ENSGALT00010061807.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038151.1", "url": "https://www.ensembl.org/id/ENSGALP00010038151.1" } ] } }, { "isoform_ac": "A0A8V1A715-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A715/entry#A0A8V1A715-1", "sequence": { "sequence": "MIWRDLSLAGWQAVLSTLPWLQCAICPPPGCRGGEAEAAFKCPLSVLQLGARPGERFWQHLIQGADVRGKNTLIHKTPSLGFAREPQRLSARGREHVHEVKRGALGSWDSCWDWRDFLKVLIGRTSLRAASVGCSGCRLLAVELTSSNTKPVVQEFQSVELSCIIKSTVTPDPRIEWKKIRDGETSYVFFDNKMQGDFATRAEILSRTSLVIKNTTRMDTATYRCEVAAPSDTKTIDEINIQLTVQVKPVTPRCTVPKAVPVGKTASLHCHENEGFPKSTYSWYRNSEPLSPDTKSNAKFQNSSYSLNPTTGTLVFHAVHKGDTGRYSCIATNDAGFAKCEEQEMEVYDLNIGGIIGGVLVVVAVLVLITLGICCAYRRGYFANSKENGESYKTPAKPDGVNYIRTDDEGDFRHKSSFVI", "length": 420, "header": "tr|A0A8V1A715-1|A0A8V1A715_CHICK Isoform 1 of Junctional adhesion molecule 3 OS=Gallus gallus OX=9031 GN=JAM3 PE=1 SV=1 CANONICAL=A0A8V1A715-1" }, "locus": { "chromosome": "24", "start_pos": 2571090, "end_pos": 2556991, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010061805.1", "url": "https://www.ensembl.org/id/ENSGALT00010061805.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038150.1", "url": "https://www.ensembl.org/id/ENSGALP00010038150.1" } ] } }, { "isoform_ac": "A0A8V1A9T6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A715/entry#A0A8V1A9T6-1", "sequence": { "sequence": "MALRRPALLLLLPLLGCRLLAVELTSSNTKPVVQEFQSVELSCIIKSTVTPDPRIEWKKIRDGETSYVFFDNKMQGDFATRAEILSRTSLVIKNTTRMDTATYRCEVAAPSDTKTIDEINIQLTVQVKPVTPRCTVPKAVPVGKTASLHCHENEGFPKSTYSWYRNSEPLSPDTKSNAKFQNSSYSLNPTTGTLVFHAVHKGDTGRYSCIATNDAGFAKCEEQEMEVYDLNIGGIIGGVLVVVAVLVLITLGICCAYRRGYFANSKENGESYKTPAKPDGVNYIRTDDEAQVFICHIRCQKNIANQQRRV", "length": 310, "header": "tr|A0A8V1A9T6-1|A0A8V1A9T6_CHICK Computationally mapped isoform of Junctional adhesion molecule 3 OS=Gallus gallus OX=9031 GN=JAM3 PE=1 SV=1 CANONICAL=A0A8V1A715-1" }, "locus": { "chromosome": "24", "start_pos": 2571131, "end_pos": 2546440, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010061810.1", "url": "https://www.ensembl.org/id/ENSGALT00010061810.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038154.1", "url": "https://www.ensembl.org/id/ENSGALP00010038154.1" } ] } }, { "isoform_ac": "A0A8V1A9U2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A715/entry#A0A8V1A9U2-1", "sequence": { "sequence": "MSLITATHNRISRTGSWCSAAGSSSLLFLQLFGTDSVWQLGGFDSAAERGAKQAGPGFAAITISSMRRGGCRLLAVELTSSNTKPVVQEFQSVELSCIIKSTVTPDPRIEWKKIRDGETSYVFFDNKMQGDFATRAEILSRTSLVIKNTTRMDTATYRCEVAAPSDTKTIDEINIQLTVQVKPVTPRCTVPKAVPVGKTASLHCHENEGFPKSTYSWYRNSEPLSPDTKSNAKFQNSSYSLNPTTGTLVFHAVHKGDTGRYSCIATNDAGFAKCEEQEMEVYDLNIGGIIGGVLVVVAVLVLITLGICCAYRRGYFANSKENGESYKTPAKPDGVNYIRTDDEGDFRHKSSFVI", "length": 354, "header": "tr|A0A8V1A9U2-1|A0A8V1A9U2_CHICK Computationally mapped isoform of Junctional adhesion molecule 3 OS=Gallus gallus OX=9031 GN=JAM3 PE=1 SV=1 CANONICAL=A0A8V1A715-1" }, "locus": { "chromosome": "24", "start_pos": 2571090, "end_pos": 2551267, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010061819.1", "url": "https://www.ensembl.org/id/ENSGALT00010061819.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038159.1", "url": "https://www.ensembl.org/id/ENSGALP00010038159.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-202733", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-202733", "resource": "Reactome", "description": "Cell surface interactions at the vascular wall" }, { "id": "R-GGA-216083", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-216083", "resource": "Reactome", "description": "Integrin cell surface interactions" } ], "orthologs": [ { "uniprot_canonical_ac": "Q9BX67-1", "protein_name": "Junctional adhesion molecule C", "gene_name": "JAM3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MALRRPPRLRLCARLPDFFLLLLFRGCLIGAVNLKSSNRTPVVQEFESVELSCIITDSQTSDPRIEWKKIQDEQTTYVFFDNKIQGDLAGRAEILGKTSLKIWNVTRRDSALYRCEVVARNDRKEIDEIVIELTVQVKPVTPVCRVPKAVPVGKMATLHCQESEGHPRPHYSWYRNDVPLPTDSRANPRFRNSSFHLNSETGTLVFTAVHKDDSGQYYCIASNDAGSARCEEQEMEVYDLNIGGIIGGVLVVLAVLALITLGICCAYRRGYFINNKQDGESYKNPGKPDGVNYIRTDEEGDFRHKSSFVI", "length": 310 }, "evidence": [ { "id": "A0A8V1A715", "url": "https://omabrowser.org/oma/group/A0A8V1A715/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9D8B7-1", "protein_name": "Junctional adhesion molecule C", "gene_name": "Jam3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALSRRLRLRLYARLPDFFLLLLFRGCMIEAVNLKSSNRNPVVHEFESVELSCIITDSQTSDPRIEWKKIQDGQTTYVYFDNKIQGDLAGRTDVFGKTSLRIWNVTRSDSAIYRCEVVALNDRKEVDEITIELIVQVKPVTPVCRIPAAVPVGKTATLQCQESEGYPRPHYSWYRNDVPLPTDSRANPRFQNSSFHVNSETGTLVFNAVHKDDSGQYYCIASNDAGAARCEGQDMEVYDLNIAGIIGGVLVVLIVLAVITMGICCAYRRGCFISSKQDGESYKSPGKHDGVNYIRTSEEGDFRHKSSFVI", "length": 310 }, "evidence": [ { "id": "A0A8V1A715", "url": "https://omabrowser.org/oma/group/A0A8V1A715/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 10, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A715", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A715" } ], "pmid": "" }, { "name": "bicellular tight junction", "id": "GO:0005923", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005923", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A715", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A715" } ], "pmid": "" }, { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A715", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A715" } ], "pmid": "" }, { "name": "Schmidt-Lanterman incisure", "id": "GO:0043220", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043220", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A715", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A715" } ], "pmid": "" }, { "name": "filamentous actin", "id": "GO:0031941", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031941", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A715", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A715" } ], "pmid": "" }, { "name": "paranodal junction", "id": "GO:0033010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033010", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A715", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A715" } ], "pmid": "" }, { "name": "cell-cell contact zone", "id": "GO:0044291", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044291", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A715", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A715" } ], "pmid": "" }, { "name": "microvillus", "id": "GO:0005902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005902", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A715", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A715" } ], "pmid": "" }, { "name": "protein complex involved in cell adhesion", "id": "GO:0098636", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098636", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A715", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A715" } ], "pmid": "" }, { "name": "desmosome", "id": "GO:0030057", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030057", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A715", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A715" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 14, "go_terms": [ { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A715", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A715" } ], "pmid": "" }, { "name": "negative regulation of integrin activation", "id": "GO:0033624", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033624", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A715", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A715" } ], "pmid": "" }, { "name": "hematopoietic stem cell migration to bone marrow", "id": "GO:0097241", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097241", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A715", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A715" } ], "pmid": "" }, { "name": "angiogenesis", "id": "GO:0001525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001525", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A715", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A715" } ], "pmid": "" }, { "name": "cell migration", "id": "GO:0016477", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016477", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A715", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A715" } ], "pmid": "" }, { "name": "cell-cell adhesion", "id": "GO:0098609", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098609", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A715", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A715" } ], "pmid": "" }, { "name": "negative regulation of cell adhesion mediated by integrin", "id": "GO:0033629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033629", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A715", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A715" } ], "pmid": "" }, { "name": "protein localization to cell surface", "id": "GO:0034394", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034394", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A715", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A715" } ], "pmid": "" }, { "name": "adherens junction assembly", "id": "GO:0034333", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034333", "evidence": [ 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"https://www.ensembl.org/id/ENSGALT00010061844.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038177.1", "url": "https://www.ensembl.org/id/ENSGALP00010038177.1" } ] } }, { "isoform_ac": "A0A8V1A761-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9X0/entry#A0A8V1A761-1", "sequence": { "sequence": "MEAANGAVPDGAAGGKGGSAAAPSGKKEVKMVIVGDGGCGKTSLLMVYAKGAFPEQYAPSVFEKYATSITIGKKEVILNLYDTAGQEDYDRLRPLSYQNTNVVLICYDVMNPTSYDNVADKWYPEVNHFCQGVPLVLIGCKTDLRKDKEQLRKLRASKQEPITYNQQAFLPGPLKSKSTNRKPVLPLL", "length": 188, "header": "tr|A0A8V1A761-1|A0A8V1A761_CHICK Computationally mapped isoform of Ras homolog family member F, filopodia associated OS=Gallus gallus OX=9031 GN=RHOF PE=3 SV=1 CANONICAL=A0A8V1A9X0-1" }, "locus": { "chromosome": "15", "start_pos": 5641966, "end_pos": 5618194, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010061856.1", "url": "https://www.ensembl.org/id/ENSGALT00010061856.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038186.1", "url": "https://www.ensembl.org/id/ENSGALP00010038186.1" } ] } }, { "isoform_ac": "A0A8V1A9X0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9X0/entry#A0A8V1A9X0-1", "sequence": { "sequence": "MEAANGAVPDGAAGGKGGSAAAPSGKKEVKMVIVGDGGCGKTSLLMVYAKGAFPEQYAPSVFEKYATSITIGKKEVILNLYDTAGQEDYDRLRPLSYQNTNVVLICYDVMNPTSYDNVADKWYPEVNHFCQGVPLVLIGCKTDLRKDKEQLRKLRASKQEPITYNQVISTGWFTNQLLSPRLSDRTPYLFQNKALQTHCAVLEELLPLWEVCARLRHCPYSI", "length": 222, "header": "tr|A0A8V1A9X0-1|A0A8V1A9X0_CHICK Isoform 1 of Ras homolog family member F, filopodia associated OS=Gallus gallus OX=9031 GN=RHOF PE=3 SV=1 CANONICAL=A0A8V1A9X0-1" }, "locus": { "chromosome": "15", "start_pos": 5641966, "end_pos": 5622930, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010061853.1", "url": "https://www.ensembl.org/id/ENSGALT00010061853.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038184.1", "url": "https://www.ensembl.org/id/ENSGALP00010038184.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-6798695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798695", "resource": "Reactome", "description": "Neutrophil degranulation" }, { "id": "R-GGA-9035034", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9035034", "resource": "Reactome", "description": "RHOF GTPase cycle" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9X0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9X0" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9X0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9X0" } ], "pmid": "" }, { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9X0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9X0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9X0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9X0" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9X0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9X0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "actin filament organization", "id": "GO:0007015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007015", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9X0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9X0" } ], "pmid": "" }, { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9X0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9X0" } ], "pmid": "" }, { "name": "cell migration", "id": "GO:0016477", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016477", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9X0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9X0" } ], "pmid": "" }, { "name": "regulation of actin cytoskeleton organization", "id": "GO:0032956", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032956", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9X0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9X0" } ], "pmid": "" }, { "name": "small GTPase-mediated signal transduction", "id": "GO:0007264", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007264", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9X0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9X0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", 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}, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AA01-1", "uniprot_ac": "A0A8V1AA01", "uniprot_id": "A0A8V1AA01_CHICK", "mass": { "chemical_mass": 53860.0, "monoisotopic_mass": 53860.0 }, "refseq": {}, "gene_names": [ { "name": "CCM2", "type": "recommended", "evidence": [ { "id": "A0A8V1AA01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA01" } ] } ], "protein_names": [ { "name": "CCM2 scaffolding protein", "type": "synonym", "evidence": [ { "id": "A0A8V1AA01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA01/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AA01", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA01" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CCM2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA01", "locus": { "chromosome": "2", "start_pos": 4037237, "end_pos": 4064323, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010025345", "url": "https://www.ensembl.org/id/ENSGALG00010025345" } ] } } ], "crossref": [ { "id": "A0A8V1AA01", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AA01", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000005612", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000005612", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd13166", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13166", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd13516", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13516", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "420410", "url": "https://www.ncbi.nlm.nih.gov/gene/420410", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006020", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006020", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026159", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026159", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032375", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032375", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:420410", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420410", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LKTXDSS", "url": "https://omabrowser.org/oma/group/LKTXDSS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2TW80", "url": "https://www.orthodb.org/?gene=A0A3Q2TW80", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZXD8", "url": "https://www.orthodb.org/?gene=A0A8V0ZXD8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A2J3", "url": "https://www.orthodb.org/?gene=A0A8V1A2J3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A2M2", "url": "https://www.orthodb.org/?gene=A0A8V1A2M2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AA01", "url": "https://www.orthodb.org/?gene=A0A8V1AA01", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AA03", "url": "https://www.orthodb.org/?gene=A0A8V1AA03", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1C144", "url": "https://www.orthodb.org/?gene=E1C144", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21642", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21642", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21642:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21642:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF16545", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16545", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A3Q2TW80", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TW80", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2TW80-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TW80-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZXD8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXD8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZXD8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXD8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A2J3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2J3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A2J3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2J3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A2M2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2M2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A2M2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2M2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AA01", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA01", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AA01-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA01-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AA03", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA03", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AA03-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA03-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C144", "url": "https://www.uniprot.org/uniprotkb/E1C144", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C144-1", "url": "https://www.uniprot.org/uniprotkb/E1C144-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "GAVAVGCSHHAHQPTSWRAVFLWSCCPPTFFREQRSNSSGWQEPGIVSPFKRVFLKGEKGRDKKAQEKVTERRPLHTVVVSLPDRVEPDILLNDYIEKEVKYLGQLTSVPGYLNPSSRTEILHLIDNAKRAHQLPGQLTQEHDAVISLSAYNIKLVWRDGEDLILRVPIHDIASVSYIRDDSAHLVVLKTAQDPGISPSQSLSAESSKALTSGSLSESGVVPVEACCLVVLATENKVTAEELCSLLSQVFQIVYTESTIDFLDRAIFDGASTPTRHMSLHSDDSSTKVDVKESYETEASTVSFPETLDAGDNSPSSFLTQQSPHIKTISESELSTTATELLQDYMMTLRTKLSSQEIQQFAMLLHEYRNGASIHEFCINLKQLYGDSRKFLLLGLRPFIPEKDSQHFENFLETIGVKDGRGIITDSFGRYRRTLSTTSNSTTNGNGAAGSSDDQSVPSEEDEWDRMISHISNDIEALGCSMDRDSS", "length": 486, "header": "tr|A0A8V1AA01-1|A0A8V1AA01_CHICK Isoform 1 of CCM2 scaffolding protein OS=Gallus gallus OX=9031 GN=CCM2 PE=1 SV=1 CANONICAL=A0A8V1AA01-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2TW80-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA01/entry#A0A3Q2TW80-1", "sequence": { "sequence": "MESEPGIVSPFKRVFLKGEKGRDKKAQEKVTERRPLHTVVVSLPDRVEPDILLNDYIEKEVKYLGQLTSVPGYLNPSSRTEILHLIDNAKRAHQLPGQLTQEHDAVISLSAYNIKLVWRDGEDLILRVPIHDIASVSYIRDDSAHLVVLKTAQDPGISPSQSLSAESSKALTSGSLSESGVVPVEACCLVVLATENKVTAEELCSLLSQVFQIVYTESTIDFLDRAIFDGASTPTRHMSLHSDDSSTKVDVKESYETEASTVSFPETLDAGDNSPSSFLTQQSPHIKTISESELSTTATELLQDYMMTLRTKLSSQEIQQFAMLLHEYRNGASIHEFCINLKQLYGDSRKFLLLGLRPFIPEKDSQHFENFLETIGVKDGRGIITDSFGRYRRTLSTTSNSTTNGNGAAGSSDDQSVPSEEDEWDRMISHISNDIEALGCSMDRDSS", "length": 447, "header": "tr|A0A3Q2TW80-1|A0A3Q2TW80_CHICK Computationally mapped isoform of CCM2 scaffolding protein OS=Gallus gallus OX=9031 GN=CCM2 PE=1 SV=1 CANONICAL=A0A8V1AA01-1" }, "locus": { "chromosome": "2", "start_pos": 4048686, "end_pos": 4039590, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010061884.1", "url": "https://www.ensembl.org/id/ENSGALT00010061884.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038206.1", "url": "https://www.ensembl.org/id/ENSGALP00010038206.1" } ] } }, { "isoform_ac": "A0A8V0ZXD8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA01/entry#A0A8V0ZXD8-1", "sequence": { "sequence": "MEEEGKKGKKPGIVSPFKRVFLKGEKGRDKKAQEKVTERRPLHTVVVSLPDRVEPDILLNDYIEKEVKDPGISPSQSLSAESSKALTSGSLSESGVVPVEACCLVVLATENKVTAEELCSLLSQVFQIVYTESTIDFLDRAIFDGASTPTRHMSLHSDDSSTKVDVKESYETEASTVSFPETLDAGDNSPSSFLTQQSPHIKTISESELSTTATELLQDYMMTLRTKLSSQEIQQFAMLLHEYRNGASIHEFCINLKQLYGDSRKFLLLGLRPFIPEKDSQHFENFLETIGVKDGRGIITDSFGRYRRTLSTTSNSTTNGNGAAGSSDDQSVPSEEDEWDRMISHISNDIEALGCSMDRDSS", "length": 362, "header": "tr|A0A8V0ZXD8-1|A0A8V1AA01_CHICK Computationally mapped isoform of CCM2 scaffolding protein OS=Gallus gallus OX=9031 GN=CCM2 PE=1 SV=1 CANONICAL=A0A8V1AA01-1" }, "locus": { "chromosome": "2", "start_pos": 4062964, "end_pos": 4039590, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010061940.1", "url": "https://www.ensembl.org/id/ENSGALT00010061940.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038244.1", "url": "https://www.ensembl.org/id/ENSGALP00010038244.1" } ] } }, { "isoform_ac": "A0A8V1A2J3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA01/entry#A0A8V1A2J3-1", "sequence": { "sequence": "MMLCYLQAQLQHQPGIVSPFKRVFLKGEKGRDKKAQEKVTERRPLHTVVVSLPDRVEPDILLNDYIEKEVKYLGQLTSVPGYLNPSSRTEILHLIDNAKRAHQLPGQLTQEHDAVISLSAYNIKLVWRDGEDLILRVPIHDIASVSYIRDDSAHLVVLKTAQDPGISPSQSLSAESSKALTSGSLSESGVVPVEACCLVVLATENKVTAEELCSLLSQVFQIVYTESTIDFLDRAIFDGASTPTRHMSLHSDDSSTKVDVKESYETEASTVSFPETLDAGDNSPSSFLTQQSPHIKTISESELSTTATELLQDYMMTLRTKLSSQEIQQFAMLLHEYRNGASIHEFCINLKQLYGDSRKFLLLGLRPFIPEKDSQHFENFLETIGVKDGRGIITDSFGRYRRTLSTTSNSTTNGNGAAGSSDDQSVPSEEDEWDRMISHISNDIEALGCSMDRDSS", "length": 456, "header": "tr|A0A8V1A2J3-1|A0A8V1AA01_CHICK Computationally mapped isoform of CCM2 scaffolding protein OS=Gallus gallus OX=9031 GN=CCM2 PE=1 SV=1 CANONICAL=A0A8V1AA01-1" }, "locus": { "chromosome": "2", "start_pos": 4048079, "end_pos": 4039590, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010061895.1", "url": "https://www.ensembl.org/id/ENSGALT00010061895.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038215.1", "url": "https://www.ensembl.org/id/ENSGALP00010038215.1" } ] } }, { "isoform_ac": "A0A8V1A2M2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA01/entry#A0A8V1A2M2-1", "sequence": { "sequence": "MATDSTAPHTYPPSPSCLRGPSPVNDPGIVSPFKRVFLKGEKGRDKKAQEKVTERRPLHTVVVSLPDRVEPDILLNDYIEKEVKYLGQLTSVPGYLNPSSRTEILHLIDNAKRAHQLPGQLTQEHDAVISLSAYNIKLVWRDGEDLILRVPIHDIASVSYIRDDSAHLVVLKTAQDPGISPSQSLSAESSKALTSGSLSESGVVPVEACCLVVLATENKVTAEELCSLLSQVFQIVYTESTIDFLDRAIFDGASTPTRHMSLHSDDSSTKVDVKESYETEASTVSFPETLDAGDNSPSSFLTQQSPHIKTISESELSTTATELLQDYMMTLRTKLSSQEIQQFAMLLHEYRNGASIHEFCINLKQLYGDSRKFLLLGLRPFIPEKDSQHFENFLETIGVKDGRGIITDSFGRYRRTLSTTSNSTTNGNGAAGSSDDQSVPSEEDEWDRMISHISNDIEALGCSMDRDSS", "length": 469, "header": "tr|A0A8V1A2M2-1|A0A8V1AA01_CHICK Computationally mapped isoform of CCM2 scaffolding protein OS=Gallus gallus OX=9031 GN=CCM2 PE=1 SV=1 CANONICAL=A0A8V1AA01-1" }, "locus": { "chromosome": "2", "start_pos": 4063450, "end_pos": 4039590, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010061943.1", "url": "https://www.ensembl.org/id/ENSGALT00010061943.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038246.1", "url": "https://www.ensembl.org/id/ENSGALP00010038246.1" } ] } }, { "isoform_ac": "A0A8V1AA01-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA01/entry#A0A8V1AA01-1", "sequence": { "sequence": "GAVAVGCSHHAHQPTSWRAVFLWSCCPPTFFREQRSNSSGWQEPGIVSPFKRVFLKGEKGRDKKAQEKVTERRPLHTVVVSLPDRVEPDILLNDYIEKEVKYLGQLTSVPGYLNPSSRTEILHLIDNAKRAHQLPGQLTQEHDAVISLSAYNIKLVWRDGEDLILRVPIHDIASVSYIRDDSAHLVVLKTAQDPGISPSQSLSAESSKALTSGSLSESGVVPVEACCLVVLATENKVTAEELCSLLSQVFQIVYTESTIDFLDRAIFDGASTPTRHMSLHSDDSSTKVDVKESYETEASTVSFPETLDAGDNSPSSFLTQQSPHIKTISESELSTTATELLQDYMMTLRTKLSSQEIQQFAMLLHEYRNGASIHEFCINLKQLYGDSRKFLLLGLRPFIPEKDSQHFENFLETIGVKDGRGIITDSFGRYRRTLSTTSNSTTNGNGAAGSSDDQSVPSEEDEWDRMISHISNDIEALGCSMDRDSS", "length": 486, "header": "tr|A0A8V1AA01-1|A0A8V1AA01_CHICK Isoform 1 of CCM2 scaffolding protein OS=Gallus gallus OX=9031 GN=CCM2 PE=1 SV=1 CANONICAL=A0A8V1AA01-1" }, "locus": { "chromosome": "2", "start_pos": 4054922, "end_pos": 4039590, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010061904.1", "url": "https://www.ensembl.org/id/ENSGALT00010061904.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038219.1", "url": "https://www.ensembl.org/id/ENSGALP00010038219.1" } ] } }, { "isoform_ac": "A0A8V1AA03-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA01/entry#A0A8V1AA03-1", "sequence": { "sequence": "QKSGKALELLNDVCQKWDQDQKPQPGIVSPFKRVFLKGEKGRDKKAQEKVTERRPLHTVVVSLPDRVEPDILLNDYIEKEVKYLGQLTSVPGYLNPSSRTEILHLIDNAKRAHQLPGQLTQEHDAVISLSAYNIKLVWRDGEDLILRVPIHDIASVSYIRDDSAHLVVLKTAQDPGISPSQSLSAESSKALTSGSLSESGVVPVEACCLVVLATENKVTAEELCSLLSQVFQIVYTESTIDFLDRAIFDGASTPTRHMSLHSDDSSTKVDVKESYETEASTVSFPETLDAGDNSPSSFLTQQSPHIKTISESELSTTATELLQDYMMTLRTKLSSQEIQQFAMLLHEYRNGASIHEFCINLKQLYGDSRKFLLLGLRPFIPEKDSQHFENFLETIGVKDGRGIITDSFGRYRRTLSTTSNSTTNGNGAAGSSDDQSVPSEEDEWDRMISHISNDIEALGCSMDRDSS", "length": 467, "header": "tr|A0A8V1AA03-1|A0A8V1AA03_CHICK Computationally mapped isoform of CCM2 scaffolding protein OS=Gallus gallus OX=9031 GN=CCM2 PE=1 SV=1 CANONICAL=A0A8V1AA01-1" }, "locus": { "chromosome": "2", "start_pos": 4056870, "end_pos": 4039590, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010061913.1", "url": "https://www.ensembl.org/id/ENSGALT00010061913.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038224.1", "url": "https://www.ensembl.org/id/ENSGALP00010038224.1" } ] } }, { "isoform_ac": "E1C144-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA01/entry#E1C144-1", "sequence": { "sequence": "MEEEGKKGKKPGIVSPFKRVFLKGEKGRDKKAQEKVTERRPLHTVVVSLPDRVEPDILLNDYIEKEVKYLGQLTSVPGYLNPSSRTEILHLIDNAKRAHQLPGQLTQEHDAVISLSAYNIKLVWRDGEDLILRVPIHDIASVSYIRDDSAHLVVLKTAQDPGISPSQSLSAESSKALTSGSLSESGVVPVEACCLVVLATENKVTAEELCSLLSQVFQIVYTESTIDFLDRAIFDGASTPTRHMSLHSDDSSTKVDVKESYETEASTVSFPETLDAGDNSPSSFLTQQSPHIKTISESELSTTATELLQDYMMTLRTKLSSQEIQQFAMLLHEYRNGASIHEFCINLKQLYGDSRKFLLLGLRPFIPEKDSQHFENFLETIGVKDGRGIITDSFGRYRRTLSTTSNSTTNGNGAAGSSDDQSVPSEEDEWDRMISHISNDIEALGCSMDRDSS", "length": 453, "header": "tr|E1C144-1|A0A8V1AA01_CHICK Computationally mapped isoform of CCM2 scaffolding protein OS=Gallus gallus OX=9031 GN=CCM2 PE=1 SV=2 CANONICAL=A0A8V1AA01-1" }, "locus": { "chromosome": "2", "start_pos": 4062964, "end_pos": 4039590, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010061929.1", "url": "https://www.ensembl.org/id/ENSGALT00010061929.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038237.1", "url": "https://www.ensembl.org/id/ENSGALP00010038237.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:420410", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420410", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I5ZT10-1", "protein_name": "CCM2 scaffold protein", "gene_name": "Ccm2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLSRCSPHPLSPLSPPVCPQHLVFYLRPRLTGILQSSCLRITFLVQPGIVSPFKRVFLKGEKSRDKKAHEKVTERRPLHTVVLALPERVEPDRLLSDYIEKEVKYLGQLTSIPGYLNPSSRTEILHFIDKAKRSHQLPGHLTQEHDAVLSLSAYNVKLAWRDGEDIILRVPIHDIAAVSYVRDDAAHLVVLKTAQDPGISPSQSLCAEGSRGLSAGSLSESAVGPVEACCLVIMATESKVAAEELCSLLSQVFQIVYTESTIDFLDRAIFDGASTPTHHLSVHSDDSSTKVDMKDSYDADASTFCFPDSGDVGGLPPLPFCMQASPHSKTVSESELSTSATELLQDYMLTLRTKLSSQEIQQFAALLHEYRNGASIHEFCISLRQLYGDSRKFLLLGLRPFIPEKDSQHFENFLETIGVKDGRGIITDSFGRHRRALSTTSTSTTNGNRTTGSPDDRSAPSEGDEWDRMISDISSDIEALGCSMDQDSA", "length": 489 }, "evidence": [ { "id": "A0A8V1AA01", "url": "https://omabrowser.org/oma/group/A0A8V1AA01/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1B8H2-1", "protein_name": "CCM2 scaffold protein", "gene_name": "CCM2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MHSNCRQRGRNQNSSREIPPQTDFPTGYPMENEPGIVSPFKRVFLKGEKSRDKKAHEKVTERRPLHTVVLSLPERVEPDRLLSDYIEKEVKYLGQLTSIPGYLNPSSRTEILHFIDNAKRAHQLPGHLTQEHDAVISLSAYNVKLAWRDGEDTILRVPIHDIAAVSYVRDDASHLVVLKTAQDPGISPSQSLCAESSRGLTTGSLSESGVGPVEACCLVILAAESKVAAEELCSLLGQVFQIVYTESTIDFLDRAIFDGASTPTHHLSLHSDDSSTKVDMKEPYETEASTFSFPECAHAGGVSPLSFCMQTAPHAKTVSESELSATAAELLQDYMLTLRTKLSSQEIQQFAALLHEYRDGASVHEFCINLRQLYGDSRKFLLLGLRPFIPEKDSQHFENFLETIGVKDGRGIITDSFGRYRRATSSTSTSTSNGNRAAGSSDDQSVPSEGDEWDRMISDISNDIEALGCSMDQDSA", "length": 476 }, "evidence": [ { "id": "A0A8V1AA01", "url": "https://omabrowser.org/oma/group/A0A8V1AA01/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1ST61-1", "protein_name": "CCM2 scaffold protein", "gene_name": "CCM2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MHGSSRQRGRNQDSSREIAAHTGFPTGCSVENEPGIVSPFKRVFLKGEKSRDKKAHEKVTERRPLHTVVLSLPERVEPDRLLSDYIEKEVKYLGQLTSIPGYLNPSSRTEILHFIDNAKRAHQLPGHLTQEHDAVISLSAYNVKLAWRDGEDTILRVPIHDIAAVSYVRDDASHLVVLKTAQDPGISPSQSLCAESSRGLTTGSLSESGVGPVEACCLVILAAESKVAAEELCSLLGQVFQIVYTESTIDFLDRAIFDGASTPTHHLSLHSDDSSTKVDLKEPYETEASTFTFPECAHAGGVSPLSFCMQTAPHAKTVSESELSATAAELLQDYMLTLRTKLSSQEIQQFAALLHEYRDGASVHEFCINLRQLYGDSRKFLLLGLRPFIPEKDSQHFENFLETIGVKDGRGIITDSFGRYRRTMSSTSTSTSNGNRAAGSSDDQSAPSEGDEWDRMISDISNDIEALGCSMDPDSA", "length": 476 }, "evidence": [ { "id": "A0A8V1AA01", "url": "https://omabrowser.org/oma/group/A0A8V1AA01/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q6DRP4-1", "protein_name": "Cerebral cavernous malformations protein 2 homolog", "gene_name": "ccm2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEEDVKKVKKPGIVSPFKRVFLKGEKGRDKKALEKSTERRALHTFSLSLPDHRIDPDILLNDYIEKEVKYLGQLTSVPGYLNPSSRTEVLQLIDNARKSHQLAGQLTSEQDAVVSLSAYNVKLVWRDGEDIILRVPIHDIAAVSYIRDDSLHLVVLKTAQEPGGSPCHSTEMSKSPTLSSLSESGAVLVEVCCLLVLAVDNKAAAEELCLLLSQVFQIVYTESTIDFLDRAIFDGATTPTRHLSIYSEDSSSKVDVKDVFEAEASTFSFQSSLEAGHSSSPSPTSAPASPQTKTASESELSTTAAELLQDYMTTLRTKLSSKEIQQFATLLHEYRNGASIHEFCINLRQLYGDSRKFLLLGLRPFIPEKDSQHFENFLETIGVKDGRGIITDSFGRYKRTTSSASDSTTNGNGAAGGSDEGTATSEGDEWDRMISDISNDIEALGSSMDQDGVPS", "length": 455 }, "evidence": [ { "id": "A0A8V1AA01", "url": "https://omabrowser.org/oma/group/A0A8V1AA01/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8K2Y9-1", "protein_name": "Cerebral cavernous malformations protein 2 homolog", "gene_name": "Ccm2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEEEGKKGKKPGIVSPFKRVFLKGEKSRDKKAHEKVTERRPLHTVVLALPERVEPDRLLSDYIEKEVKYLGQLTSIPGYLNPSSRTEILHFIDKAKRSHQLPGHLTQEHDAVLSLSAYNVKLAWRDGEDIILRVPIHDIAAVSYVRDDAAHLVVLKTAQDPGISPSQSLCAESSRGLSAGSLSESAVGPVEACCLVIMATESKVAAEELCSLLSQVFQIVYTESTIDFLDRAIFDGASTPTHHLSLHSDDSSTKVDMKDSYDADASTFCFPDSGDVGGLPPLPFCMQTSPHSKTVSESELSTSATELLQDYMLTLRTKLSSQEIQQFAALLHEYRNGASIHEFCISLRQLYGDSRKFLLLGLRPFIPEKDSQHFENFLETIGVKDGRGIITDSFGRHRRALSTTSTSTINGNRTTGSPDDRSAPSEGDEWDRMISDISSDIEALGCSMDQDSA", "length": 453 }, "evidence": [ { "id": "A0A8V1AA01", "url": "https://omabrowser.org/oma/group/A0A8V1AA01/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9BSQ5-1", "protein_name": "Cerebral cavernous malformations 2 protein", "gene_name": "CCM2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEEEGKKGKKPGIVSPFKRVFLKGEKSRDKKAHEKVTERRPLHTVVLSLPERVEPDRLLSDYIEKEVKYLGQLTSIPGYLNPSSRTEILHFIDNAKRAHQLPGHLTQEHDAVLSLSAYNVKLAWRDGEDIILRVPIHDIAAVSYVRDDAAHLVVLKTAQDPGISPSQSLCAESSRGLSAGSLSESAVGPVEACCLVILAAESKVAAEELCCLLGQVFQVVYTESTIDFLDRAIFDGASTPTHHLSLHSDDSSTKVDIKETYEVEASTFCFPESVDVGGASPHSKTISESELSASATELLQDYMLTLRTKLSSQEIQQFAALLHEYRNGASIHEFCINLRQLYGDSRKFLLLGLRPFIPEKDSQHFENFLETIGVKDGRGIITDSFGRHRRALSTTSSSTTNGNRATGSSDDRSAPSEGDEWDRMISDISSDIEALGCSMDQDSA", "length": 444 }, "evidence": [ { "id": "A0A8V1AA01", "url": "https://omabrowser.org/oma/group/A0A8V1AA01/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "vasculogenesis", "id": "GO:0001570", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001570", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AA01", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA01" } ], "pmid": "" }, { "name": "heart development", "id": "GO:0007507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007507", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AA01", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA01" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AA01", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA01" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AA01", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA01" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 37, "end_pos": 39, "annotation": "n_glycosylation_sequon" }, { "start_pos": 439, "end_pos": 441, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AA01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA01" }, { "id": "PS01179", "database": "PROSITE", "url": "https://prosite.expasy.org/PS01179" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PID", "eco_id": "ECO_0000259", "start_pos": 100, "end_pos": 256, "start_aa": "Val", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 37, "end_pos": 39 }, { "start_pos": 439, "end_pos": 441 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AA47-1", "uniprot_ac": "A0A8V1AA47", "uniprot_id": "A0A8V1AA47_CHICK", "mass": { "chemical_mass": 117430.0, "monoisotopic_mass": 117430.0 }, "refseq": {}, "gene_names": [ { "name": "MYO1G", "type": "recommended", "evidence": [ { "id": "A0A8V1AA47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA47" } ] } ], "protein_names": [ { "name": "Myosin IG", "type": "synonym", "evidence": [ { "id": "A0A8V1AA47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA47/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AA47", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA47" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MYO1G", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA47", "locus": { "chromosome": "2", "start_pos": 4075058, "end_pos": 4066231, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010025377", "url": "https://www.ensembl.org/id/ENSGALG00010025377" } ] } } ], "crossref": [ { "id": "A0A8V1AA47", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AA47", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd01378", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01378", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001609", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001609", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010926", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010926", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036072", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036072", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZXI6", "url": "https://www.orthodb.org/?gene=A0A8V0ZXI6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AA47", "url": "https://www.orthodb.org/?gene=A0A8V1AA47", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AA55", "url": "https://www.orthodb.org/?gene=A0A8V1AA55", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13140", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13140", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13140:SF381", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13140:SF381", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00063", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00063", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF06017", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06017", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZXI6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXI6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZXI6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXI6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AA47", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA47", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AA47-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA47-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AA55", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA55", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AA55-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA55-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MCMCVSVCPGVCVPPWCPALPACTHGCCLQEGLLSLCPVWPHSMKLGDTPCPTATPVCRFSKGRIYTYIGEVVVAMNPYQPLELYGPSVVEQYQGRELYERPPHLFALADAAYKAMKRRAKDTCIVISGESGAGKTEASKYIMQYIAAITNPTQRAEVERVKNVLLKSNCVLEAFGNAKTNRNDNSSRFGKYMDINFDFKGDPTGGHIYNYLLEKSRVLQQQPGERNFHSFYQLLLGAPDALLASLHLQRDPTAYCYTQQGTQGSAGGDDARGYRAVEEAMAVIGFTPEEVGAVQRILAAILHLGNVQFVAEGEVAALEAVEQLAVLAQLTGTTPEQLRQALLARTVATGGGELIEKGHSPTEAAYGRDACAKAIYERLFGWIVGRINASITARGYDVRQHGKSTVIGVLDIYGFEIFDTNSFEQFCINYCNEKLQQLFIELILRQEQAEYQREGITWQNIEYFSNEPIVELVEQPHRGILALLDEACLAVGTVTDALFLANMDARLGHHPHYSSRKLCPTDKTMEFDRDFRIKHYAGDVTYSVEGFLDKNKDTLFQDFKRLLYNSMDPVLRAMWPDGEQSITEVTKRPLTAATLFKNSIVALVENLASKEPYYVRCIKPNDQKSPVLFDEERCRHQVAYLGLLENVRVRRAGFAYRQPYDRFLQRYKMTCEYTWPNHLMATDREATQTLLEQHGFQDDVAYGHTKVFIRTPRTLFCLEQERAQLIPIIVLLLQKAWRGALARRWCRYLRAAYAIMGYYKRHKVKAYLLELIRRFQGVRSMPDFGKSLAWPEPPAVLSRFQENSQQLFRRWRARQIVKNIPPSDMAQIRAKVAAMGALHGLRKDWGCQRGWVRDYLSSASENPGLALPFAHRVQALRDKVHFGAVLFSSHVRKINRFNKSRDRAILITDQHLYKLEPRKQYRVMRELPLSMVTGLSVTSCRAQLVVFHTQNHDDLAVCLHKTQPRGDERVGELVGVLLEHCRTTKRELQVHVSDRIQLSLRGRKRLLTVETQPDVAAPDFRKSRDGFVLYWPGS", "length": 1034, "header": "tr|A0A8V1AA47-1|A0A8V1AA47_CHICK Isoform 1 of Myosin IG OS=Gallus gallus OX=9031 GN=MYO1G PE=3 SV=1 CANONICAL=A0A8V1AA47-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZXI6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA47/entry#A0A8V0ZXI6-1", "sequence": { "sequence": "MAELEGPEFGKADFVLLDEVTMEHFMENLRLRFSKGRIYTYIGEVVVAMNPYQPLELYGPSVVEQYQGRELYERPPHLFALADAAYKAMKRRAKDTCIVISGESGAGKTEASKYIMQYIAAITNPTQRAEVERVKNVLLKSNCVLEAFGNAKTNRNDNSSRFGKYMDINFDFKGDPTGGHIYNYLLEKSRVLQQQPGERNFHSFYQLLLGAPDALLASLHLQRDPTAYCYTQQGTQGSAGGDDARGYRAVEEAMAVIGFTPEEVGAVQRILAAILHLGNVQFVAEGEVAALEAVEQLAVLAQLTGTTPEQLRQALLARTVATGGGELIEKGHSPTEAAYGRDACAKAIYERLFGWIVGRINASITARGYDVRQHGKSTVIGVLDIYGFEIFDTNSFEQFCINYCNEKLQQLFIELILRQEQAEYQREGITWQNIEYFSNEPIVELVEQPHRGILALLDEACLAVGTVTDALFLANMDARLGHHPHYSSRKLCPTDKTMEFDRDFRIKHYAGDVTMDPVLRAMWPDGEQSITEVTKRPLTAATLFKNSIVALVENLASKEPYYVRCIKPNDQKSPVLFDEERCRHQVAYLGLLENVRVRRAGFAYRQPYDRFLQRYKMTCEYTWPNHLMATDREATQTLLEQHGFQDDVAYGHTKVFIRTPRTLFCLEQERAQLIPIIVLLLQKAWRGALARRWCRYLRAAYAIMGYYKRHKVKAYLLELIRRFQGVRSMPDFGKSLAWPEPPAVLSRFQENSQQLFRRWRARQIVKNIPPSDMAQIRAKVAAMGALHGLRKDWGCQRGWVRDYLSSASENPGLALPFAHRVQALRDKVHFGAVLFSSHVRKINRFNKSRDRAILITDQHLYKLEPRKQYRVMRELPLSMVTGLSVTSCRAQLVVFHTQNHDDLAVCLHKTQPRGDERVGELVGVLLEHCRTTKRELQVHVSDRIQLSLRGRKRLLTVETQPDVAAPDFRKSRDGFVLYWPGS", "length": 982, "header": "tr|A0A8V0ZXI6-1|A0A8V1AA47_CHICK Computationally mapped isoform of Myosin IG OS=Gallus gallus OX=9031 GN=MYO1G PE=3 SV=1 CANONICAL=A0A8V1AA47-1" }, "locus": { "chromosome": "2", "start_pos": 4074867, "end_pos": 4066294, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010062010.1", "url": "https://www.ensembl.org/id/ENSGALT00010062010.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038300.1", "url": "https://www.ensembl.org/id/ENSGALP00010038300.1" } ] } }, { "isoform_ac": "A0A8V1AA47-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA47/entry#A0A8V1AA47-1", "sequence": { "sequence": "MCMCVSVCPGVCVPPWCPALPACTHGCCLQEGLLSLCPVWPHSMKLGDTPCPTATPVCRFSKGRIYTYIGEVVVAMNPYQPLELYGPSVVEQYQGRELYERPPHLFALADAAYKAMKRRAKDTCIVISGESGAGKTEASKYIMQYIAAITNPTQRAEVERVKNVLLKSNCVLEAFGNAKTNRNDNSSRFGKYMDINFDFKGDPTGGHIYNYLLEKSRVLQQQPGERNFHSFYQLLLGAPDALLASLHLQRDPTAYCYTQQGTQGSAGGDDARGYRAVEEAMAVIGFTPEEVGAVQRILAAILHLGNVQFVAEGEVAALEAVEQLAVLAQLTGTTPEQLRQALLARTVATGGGELIEKGHSPTEAAYGRDACAKAIYERLFGWIVGRINASITARGYDVRQHGKSTVIGVLDIYGFEIFDTNSFEQFCINYCNEKLQQLFIELILRQEQAEYQREGITWQNIEYFSNEPIVELVEQPHRGILALLDEACLAVGTVTDALFLANMDARLGHHPHYSSRKLCPTDKTMEFDRDFRIKHYAGDVTYSVEGFLDKNKDTLFQDFKRLLYNSMDPVLRAMWPDGEQSITEVTKRPLTAATLFKNSIVALVENLASKEPYYVRCIKPNDQKSPVLFDEERCRHQVAYLGLLENVRVRRAGFAYRQPYDRFLQRYKMTCEYTWPNHLMATDREATQTLLEQHGFQDDVAYGHTKVFIRTPRTLFCLEQERAQLIPIIVLLLQKAWRGALARRWCRYLRAAYAIMGYYKRHKVKAYLLELIRRFQGVRSMPDFGKSLAWPEPPAVLSRFQENSQQLFRRWRARQIVKNIPPSDMAQIRAKVAAMGALHGLRKDWGCQRGWVRDYLSSASENPGLALPFAHRVQALRDKVHFGAVLFSSHVRKINRFNKSRDRAILITDQHLYKLEPRKQYRVMRELPLSMVTGLSVTSCRAQLVVFHTQNHDDLAVCLHKTQPRGDERVGELVGVLLEHCRTTKRELQVHVSDRIQLSLRGRKRLLTVETQPDVAAPDFRKSRDGFVLYWPGS", "length": 1034, "header": "tr|A0A8V1AA47-1|A0A8V1AA47_CHICK Isoform 1 of Myosin IG OS=Gallus gallus OX=9031 GN=MYO1G PE=3 SV=1 CANONICAL=A0A8V1AA47-1" }, "locus": { "chromosome": "2", "start_pos": 4074867, "end_pos": 4066691, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010061980.1", "url": "https://www.ensembl.org/id/ENSGALT00010061980.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038275.1", "url": "https://www.ensembl.org/id/ENSGALP00010038275.1" } ] } }, { "isoform_ac": "A0A8V1AA55-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA47/entry#A0A8V1AA55-1", "sequence": { "sequence": "MAELEGPEFGKADFVLLDEVTMEHFMENLRLRFSKGRIYTYIGEVVVAMNPYQPLELYGPSVVEQYQGRELYERPPHLFALADAAYKAMKRRAKDTCIVISGRGQVGGTPGSRVPMGAHLAHLLPVPGESGAGKTEASKYIMQYIAAITNPTQRAEVERVKNVLLKSNCVLEAFGNAKTNRNDNSSRFGKYMDINFDFKGDPTGGHIYNYLLEKSRVLQQQPGERNFHSFYQLLLGAPDALLASLHLQRDPTAYCYTQQGTQGSAGGDDARGYRAVEEAMAVIGFTPEEVGAVQRILAAILHLGNVQFVAEGEVAALEAVEQLAVLAQLTGTTPEQLRQALLARTVATGGGELIEKGHSPTEAAYGRDACAKAIYERLFGWIVGRINASITARGYDVRQHGKSTVIGVLDIYGFEIFDTNSFEQFCINYCNEKLQQLFIELILRQEQAEYQREGITWQNIEYFSNEPIVELVEQPHRGILALLDEACLAVGTVTDALFLANMDARLGHHPHYSSRKLCPTDKTMEFDRDFRIKHYAGDVTYSVEGFLDKNKDTLFQDFKRLLYNSMDPVLRAMWPDGEQSITEVTKRPLTAATLFKNSIVALVENLASKEPYYVRCIKPNDQKSPVLFDEERCRHQVAYLGLLENVRVRRAGFAYRQPYDRFLQRYKMTCEYTWPNHLMATDREATQTLLEQHGFQDDVAYGHTKVFIRTPRTLFCLEQERAQLIPIIVLLLQKAWRGALARRWCRYLRAAYAIMGYYKRHKVKAYLLELIRRFQGVRSMPDFGKSLAWPEPPAVLSRFQENSQQLFRRWRARQIVKNIPPSDMAQIRAKVAAMGALHGLRKDWGCQRGWVRDYLSSASENPGLALPFAHRVQALRDKVHFGAVLFSSHVRKINRFNKSRDRAILITDQHLYKLEPRKQYRVMRELPLSMVTGLSVTSCRAQLVVFHTQNHDDLAVCLHKTQPRGDERVGELVGVLLEHCRTTKRELQVHVSDRIQLSLRGRKRLLTVETQPDVAAPDFRKSRDGFVLYWPGS", "length": 1033, "header": "tr|A0A8V1AA55-1|A0A8V1AA55_CHICK Computationally mapped isoform of Myosin IG OS=Gallus gallus OX=9031 GN=MYO1G PE=3 SV=1 CANONICAL=A0A8V1AA47-1" }, "locus": { "chromosome": "2", "start_pos": 4074867, "end_pos": 4066294, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010061991.1", "url": "https://www.ensembl.org/id/ENSGALT00010061991.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038285.1", "url": "https://www.ensembl.org/id/ENSGALP00010038285.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 9, "go_terms": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AA47", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA47" } ], "pmid": "" }, { "name": "calmodulin binding", "id": "GO:0005516", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005516", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AA47", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA47" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AA47", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA47" } ], "pmid": "" }, { "name": "cytoskeletal motor activity", "id": "GO:0003774", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003774", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AA47", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA47" } ], "pmid": "" }, { "name": "phosphatidylinositol-4,5-bisphosphate binding", "id": "GO:0005546", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005546", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AA47", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA47" } ], "pmid": "" }, { "name": "phosphatidylinositol-3,4,5-trisphosphate binding", "id": "GO:0005547", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005547", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AA47", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA47" } ], "pmid": "" }, { "name": "phosphatidylinositol-3,4-bisphosphate binding", "id": "GO:0043325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043325", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AA47", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA47" } ], "pmid": "" }, { "name": "actin filament binding", "id": "GO:0051015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051015", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AA47", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA47" } ], "pmid": "" }, { "name": "microfilament motor activity", "id": "GO:0000146", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000146", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AA47", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA47" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 10, "go_terms": [ { "name": "cell projection", "id": "GO:0042995", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042995", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AA47", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA47" } ], "pmid": "" }, { "name": "myosin complex", "id": "GO:0016459", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016459", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AA47", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA47" } ], "pmid": "" }, { "name": "phagocytic cup", "id": "GO:0001891", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001891", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AA47", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA47" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AA47", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA47" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AA47", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA47" } ], "pmid": "" }, { "name": "actin cytoskeleton", "id": "GO:0015629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015629", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AA47", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA47" } ], "pmid": "" }, { "name": "lamellipodium", "id": "GO:0030027", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030027", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AA47", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA47" } ], "pmid": "" }, { "name": "filopodium", "id": "GO:0030175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030175", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AA47", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA47" } ], "pmid": "" }, { "name": "leading edge membrane", "id": "GO:0031256", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031256", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AA47", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA47" } ], "pmid": "" }, { "name": "microvillus", "id": "GO:0005902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005902", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AA47", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA47" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "endocytosis", "id": "GO:0006897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006897", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AA47", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA47" } ], "pmid": "" }, { "name": "actin filament organization", "id": "GO:0007015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007015", "evidence": [ { "database": "UniProtKB", 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Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052540.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015132576", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015132576" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7J1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7J1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MTERF4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7J1", "locus": {} } ], "crossref": [ { "id": "A0A8V1A7J1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A7J1", "database": "AlphaFoldDB", "categories": [] }, { "id": "107051861", "url": "https://www.ncbi.nlm.nih.gov/gene/107051861", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003690", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003690", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038538", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038538", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:107051861", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:107051861", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZXJ1", "url": "https://www.orthodb.org/?gene=A0A8V0ZXJ1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A7J1", "url": "https://www.orthodb.org/?gene=A0A8V1A7J1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PF02536", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02536", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015132576", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015132576", "database": "RefSeq", "categories": [ "Protein" ] 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transcription termination factor 4 OS=Gallus gallus OX=9031 GN=MTERF4 PE=4 SV=1 CANONICAL=A0A8V1A7J1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZXJ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7J1/entry#A0A8V0ZXJ1-1", "sequence": { "sequence": "MAGRLLGLLRARAPRAVLPAPGPASRHRCGTAGPEEGEAAELLAMGFSQAQARRLRLLRPGLEPQRRAEAAAQLLLLGLSAEAALGLLERSPGLLRMETARLKERAEYLRRLGLEGARLQSAAGRCPEVFTLPRRRMEAVVRLLRERCLFTAEQLTELLRSCPEVLLEEPDRVQHHFQYAYFRMGVRQKEMVKARLFRTPFAELRNRHVFLERRGLYRTPHKGQSQSGNPALRDVLRPTEGDFVAGVARASPDEYEVFKRLLAREEEEMEEEEEEDEEEEEEEEGSAALHAEGGDRDWHSSEPSPIAPCPPAPQ", "length": 314, "header": "tr|A0A8V0ZXJ1-1|A0A8V1A7J1_CHICK Computationally mapped isoform of Mitochondrial transcription termination factor 4 OS=Gallus gallus OX=9031 GN=MTERF4 PE=4 SV=1 CANONICAL=A0A8V1A7J1-1" }, "locus": { "chromosome": "9", "start_pos": 4567189, "end_pos": 4566097, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010062019.1", "url": 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"protein_name": "T cell receptor alpha variable 6D-6", "gene_name": "Trav6-6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDSSPGFVAVILLILGRTHGDSVTQTEGPVTVSESESLIINCTYSATSIAYPNLFWYVRYPGEGLQLLLKVITAGQKGSSRGFEATYNKETTSFHLQKASVQESDSAVYYCALG", "length": 114 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A075B625-1", "protein_name": "T cell receptor alpha variable 4N-3", "gene_name": "Trav4n-3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MERNLGAVLGILWVQICWVSGDKVKQSPSALSLQEGTNSALRCNFSIAATTVQWFLQNPRGSLMNLFYLVPGTKENGRLKSAFDSKESYSTLHIRDAQLEDSGTYFCAAE", "length": 110 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A075B695-1", "protein_name": "T cell receptor alpha variable 9D-3", "gene_name": "Trav9d-3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLLALLPVLGIHFLLRDAQAQSVTQPDARVTVSEGASLQLRCKYSYFGTPYLFWYVQYPRQGLQLLLKYYPGDPVVQGVNGFEAEFSKSNSSFHLRKASVHWSDWAVYFCAVS", "length": 113 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A075B6B4-1", "protein_name": "T cell receptor alpha variable 6-4", "gene_name": "Trav6-4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNTSPVLVTVMLLFMLGMRKTHGDSVTQKQGQVTLSEDDFLFINCTYSTTTYPTLLWYVQYLGQGPQLLLKVTTANNKGISRGFEATYDKGTTSFHLQKASVQESDSAVYFCALV", "length": 115 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A075B6D8-1", "protein_name": "T cell receptor alpha variable 3-3", "gene_name": "Trav3-3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "GEQVEQRPPHLSVREGDSAVITCTYTDPNSYYFFWYKQEPGASLQLLMKVFSSTEINEGQGFTVLLNKKDKRLSLNLTAAHPGDSAAYFCAV", "length": 92 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A075B759-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase A-like 4E", "gene_name": "PPIAL4E", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVNSVVFFEITRDGKPLGRISIKLFADKIPKTAENFRALSTGEKGFRYKGSCFHRIIPGFMCQGGDFTRPNGTGDKSIYGEKFDDENLIRKHTGSGILSMANAGPNTNGSQFFICAAKTEWLDGKHVAFGKVKERVNIVEAMEHFGYRNSKTSKKITIADCGQF", "length": 164 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A075B767-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase A-like 4H", "gene_name": "PPIAL4H", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVNSVVFFDITVDGKPLGRISIKLFADKIPKTAENFRALSTGEKGFRYKGSCFHRIIPGFMCQGGDFTRPNGTDDKSIYGEKFDDENLIRKHTGSGILSMVNAGPNTNGSQLFICTAKTEWLDGKHVAFGKVKERVNIVEAMEHFGYRNSKTSKKITIADCGQF", "length": 164 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A087WP50-1", "protein_name": "Secretoglobin, family 1B, member 15", "gene_name": "Scgb1b17", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMLAGAVVIFGVALLLLSSWGDCGICPAMKEDVHLFLNGTSEEYVEYVKQYKDDPEILENTEKIKQCVDSTLMEEDKAHANGFIEKIEASPLC", "length": 93 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WPA9-1", "protein_name": "Secretoglobin, family 2B, member 18", "gene_name": "Scgb2b18", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLGLLVTGELSFQTSEACVSFFEGYASVLSGSRVWLYQELQAFDATAEEKVALEKIQSCYSEERIRNILLEPKIMEAMVASPECRSYHSFNNFRSILDFISNLLGE", "length": 112 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WPG5-1", "protein_name": "Predicted gene 13283", "gene_name": "Gm13283", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLPVHLFLVGGVMLSCSPASSLDSGKSGSLHLERSETARFLADLRSVPGHQCLRDRTDFPCPWKEGTNITQMTLGETTSCYSQSLRQVLHRFDTEASRAAWHERALDQLLSSLWRELQVLKRPREQGQSCPLPFALAIRTYFRGFFRYLKAKAHSACSWEIVRVQLQVDLPAFPLSARRGPR", "length": 182 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WPY7-1", "protein_name": "RNA binding motif protein Y-linked family member 4", "gene_name": "Rbmyf4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAETNQPGKIFIGGLNIKTRQKTLQEIFGRFGPVARVILMRDRETKKSRGFAFLTFRRLADAKNAVKEMNGVILDGKRIKVKQARRPSSLESGSKKRPPSFSRTRGASRILKCGRGGRSRARSGPSCEGNLGGDRYTPNFNVSSSGRHFAVKRNPSSKRDDPPSKR", "length": 166 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WQA9-1", "protein_name": "Secretoglobin, family 2B, member 21", "gene_name": "Scgb2b21", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLGLLVTGELSFQTTEACVPFFEGYASVVSGSRVWMYQEFQAFDATAEEKVALEKIQGCYREESLRNILLEPKIMEAMVASPECLSYYSSNNIRCILDLLSKLLGQ", "length": 112 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WQJ0-1", "protein_name": "Secretoglobin, family 1B, member 11", "gene_name": "Scgb1b11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKLVAAVVILGAALLLLTSGGDCGICPAIKEDVRLFLNGTSEEYVEYVKQYKDDPVILENTAKINQCVDSTLTEKDMTHTTTFLKKIEDSLLC", "length": 93 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WQP8-1", "protein_name": "Predicted gene, 21698", "gene_name": "Gm21698", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRVNVDGRETREGRKDADLPSERNEGRRRWTWRMCMAHGQTTSPVPVKSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTKGSMNKRPYHRQTRHYKELKLKEKEIMTFLHDLEMKNMEARENNQELKKEKNFYRNLHTRILLGENLIKKKLAILQQESKEIHADWAIIQQRLVELNLSGKDEQEKTSNLEAQENQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPSSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WR36-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r90", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSQNEAMKTTEEVALQIVLLCQFGIGTMANILLFIHNFSPLLTGCQLRPKQVICTNMAVSSILILFMTVFPNNVFVVQRNLMNDLQCKLEYFLRMVARSINLCSTCVLSTYQFVTLLPGNFGEMMVRGRRSKVISYSCCSCWLFGVLYNVYIPMKVSGPQNTHNKTDIKSKWFCVTSGFSVGIMFLWFAHDAIFISIMIWTSVSMVLLLYRHYQRLQYIFPPHQGTRGYAEIRAAHSIAMLVVTFVSFYLLHCICFILHIVFVDSRLWLRHVGEVLTSSFPTISPLLLIFRDPSYPCSLIFNYRKPVI", "length": 309 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WR44-1", "protein_name": "BTB domain containing 35, family member 15", "gene_name": "Btbd35f15", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIHALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYVLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WR49-1", "protein_name": "Secretoglobin, family 2B, member 11", "gene_name": "Scgb2b11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLGLLVTGELSFQTSEACVSFFEGYASVLSGSRVWLYQELQAFDATAEEKVALEKIQGCYSEERIRNILLEPKIMEAMVASPECRSYHSLNNFRSILEFISNLLGE", "length": 112 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WSM5-1", "protein_name": "Predicted gene 29049", "gene_name": "Gm29049", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTSLKKKSRRKPSSQALGNIVGCRISYGWKEGNEPVTHWKAIILGQLPTNPSLYLVKYDGIDSVYGQELHSDERILNLKVLPHKVVFLQVRDVHLASALVCREVQHKFEGKDGSEDNWSGMVLAQVPFLQDYFYISYKKDPVLYVYQLLDDYKEGNLHIIPETPLAEARSGDDNDFLIGSWVQYTRDDGSKKFGKVVYKVLANSTVYCIKFLGDLHIYVYTLVSNIT", "length": 227 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WSN2-1", "protein_name": "BTB domain containing 35, family member 16", "gene_name": "Btbd35f16", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLLFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLNFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WUL8-1", "protein_name": "NBPF family member NBPF19", "gene_name": "NBPF19", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVVSAGPWSSEKAEMNILEINETLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLFHSQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPREMQKAEEKEVPEDSLEECAITYSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSIPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELVEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSIPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELVEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSIPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELVEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSIPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELVEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSIPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELVEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSIPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLAEKEPEVLQDPLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLAEKEPEVLQDPLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLAEKEPEVLQDPLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLNSVLMEVEEPEVLQDSLDGCYSTPSMYFELPDSFQHYRSVFYSFEEEHISFALYLDNRFFTLTVTSLHLVFQMLVIFPQ", "length": 3843 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A087WXS9-1", "protein_name": "TBC1 domain family member 3I", "gene_name": "TBC1D3I", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPLTAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNTEEMKMKNPGRYQIMKEKGKRSSEHIQRIDRDVSGTLRKHIFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQEHVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPITRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKQGDLPPPAKPEQGSSASRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGAVREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWVRAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHLESSQFPPGF", "length": 549 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A087X179-1", "protein_name": "TBC1 domain family member 3E", "gene_name": "TBC1D3E", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPLTAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDQAYKGMPMNIRGPMWSVLLNTEEMKLKNPGRYQIMKEKGKKSSEHIQRIDRDVSGTLRKHIFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQEHVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPITRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKKGDLPPPAKPEQGSSASRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGAVREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWVRAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHLESSQFPPGF", "length": 549 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A0A0MQP3-1", "protein_name": "BTB domain containing 35, family member 12", "gene_name": "Btbd35f12", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDSDLSITPLEVPQGLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYVLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0A6YW58-1", "protein_name": "Immunoglobulin heavy variable V8-2", "gene_name": "Ighv8-2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGRLTFSFLLLLPVPAYVLSQVTLKVSGPGILQPSQTLSLACTFSGISLSTSGMGLSWLRKPSGKALEWLASIWNNDNYYNPSLKSRLTISKETSNYQVFLKLTSVDTADSATYYGAWR", "length": 119 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0A6YXW2-1", "protein_name": "Predicted gene, 20773", "gene_name": "Gm20773", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLMKKRRRKSSSNTLRNIVGCRISHSWKEGNEPVTQWKAIVLDQLPTNPSLYLVKYDGIDSIYGLELYSDDRILNLKVLPPIVVFPQVRDAHLARALVGRAVQHKFEGKDGSEVNWRGVVLAQVPIMKDLFYITYKKDPALYAYQLLDDYKEGNLHMIPDTPPAEERSGDDSDVLIGNWVEYTRKDGSKKFGKVVYQVLANPSVYFIKFHGDIHIYVYTMVPKIFKVEKS", "length": 232 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0A6YXX7-1", "protein_name": "Predicted gene, 20807", "gene_name": "Gm20807", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLMKKRRRKSSSNTLRNIVGCRISHSWKEGNEPVTQWKAIVLDQLPTNPSLYLVKYDGIDSIYGLELYSDDRILNLKVLPPIVVFPQVRDAHLARALVGRAVQHTFEGKDGSEVNWRGVVLAQVPIMKDLFYITYKKDPALYAYQLLDDYKEGNLHMIPDTPPAEERSGDDSDVLIGNWVEYTRKDGSKKFGKVVYQVLANPSVYFIKFHGDIHIYVYTMVPKVLEVEKS", "length": 232 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0B4J1J8-1", "protein_name": "T cell receptor gamma, variable 4", "gene_name": "Trgv4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKNPGSQALLPLYLPWEANLADENPLLKVVIFLCLLTFGHGKLEQPEISISRPRDETAQISCKVFIESFRSVTIHWYRQKPNQGLEFLLYVLATPTHIFLDKEYKKMEASKNPSASTSILTIYSLEEEDEAIYYCSYG", "length": 138 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0G2JE01-1", "protein_name": "Predicted gene, 21663", "gene_name": "Gm21663", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRVNVDGRETREGRKDADPPSERNEGRRRWTWRMCMAHRQTTSPVPVKSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTFLHDLEMKNMEARENNQELKKEKNFYRNLHTRILLGENLIKKKLAILQQESKEIHADWAIIQQRLVELNLSGKDEQEKTSNLEAQENQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPSSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0G2JGR8-1", "protein_name": "Predicted gene, 21680", "gene_name": "Gm21680", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRANVDGRETREGRKDADLPSESNEGRRRWTWRMWMAHRQTTSPVPVTSKKQFEKEEKELIKKIQLTTKEINELRDRLIYVTKGSMNKRPYHRQTRHYKELKLKEKEIMTYLHELEMKNMEARENKQELKKEKNFYRNLHTRILLEENLIKKKLVILQQESKEVHADWATIHQSLVELNLSGKDEQEKTSNLETQEHQVSEAARELVLATAEEDSILQNELPCQEAPAEHHPQHPPSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0G2JMD5-1", "protein_name": "PRAME family member 33", "gene_name": "PRAMEF33", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSLQAPSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWPFLRLPLGSLMKTPHLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLQDVDENFWTIWSGARVLSCSPEAMSKRQTVEDCPRMGEHQPLKVFIDLCLKESTLDECLSYLFGWIHYRRGLVHLCCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSNLRELFLAFGYERELYVSVQWPCIPDLDSPFLCLYYPQMLYIKKISNIKEHLEHLLRYLKNPLGAFIFSDAYLADRDMECLSQYPSLSQLKELRLIHILMWTTNLQPLGALLEKVAATLKTLVLKDCRIQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTRGLSKLGLELYPAPLESLDYKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPTCGSWPSEKVDFHLCS", "length": 474 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A0G2JNH3-1", "protein_name": "Olfactory receptor", "gene_name": "LOC124905359", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKIANNTVVTEFILLGLTQSQDIQLLVFVLILIFYLIILPGNFLIIFTIRSDPGLTAPLYFFLGNLAFLDASYSFIVAPRMLVDFFSEKKVISYRGCITQLFFLHFLGGGEGLLLVVMAFDRYIAICRPLHCSTVMNPRACYAMMLALWLGGFVHSIIQVVLILRLPFCGPNQLDNFFCDVRQVIKLACTDMFVVELLMVFNSGLMTLLCFLGLLASYAVILCHVRRAASEGKNKAMSMCTTRVIIILLMFGPAIFIYMCPFRALPADKMVSLFHTVIFPLMNPMIYTLRNQEVKTSMKRLLSRHVVCQVDFIIRN", "length": 316 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A0G2JTV6-1", "protein_name": "RIKEN cDNA 4931429L15 gene like", "gene_name": "4931429L15Rikl", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQFNPFSQDTWRHGHRRAYSNISERLSCLTLQEPSVSHLYQIFSPGDRRSYLLDDSLSNSIQRESLAVPMGLEDSGSRGQQKQQQPGAVLEDLEEQEIAPTDVKYRLQLLDEAPLRSKSSSVQSQGHKPGWIPSSKTHREWFKPWKMDMTYPENERSHSGHTQGRRMTPRAQWRHVEYDSQDQDTQSPVWSQALFPGLDKSSQGVIQCTQHVSREREMVSGWSMTHAPQEMGQAKQGPAFLKTKGTAKFNVATTARMSCLPPLKLLEKKVKSRCPPNTPGIFQDWRAQPQGLYGSDERLLAPFEDQVNTRVTYMPLFTEKVKFVSPKTAVSNPKQTHSQLSRTNQPAFPGQFRNWTSGREHLEKGLPE", "length": 368 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2JVP7-1", "protein_name": "40S ribosomal protein S26", "gene_name": "Rps26-ps4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTKKRRNNGRTKKGRGHVQPIGCANCSWCVPKDKAIKKFVIWNIVETAAVRDISEARIFDAYVLPKLYVKLHYCVSLAIHSKVIRNQSHEARKDRTSPPRFRPAGAAPRPPPKPM", "length": 115 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2JW93-1", "protein_name": "High mobility group protein B4", "gene_name": "Hmgb4l4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGKDSKVRPKVNVSPYVHFMMDFRNQTREQQPNTYYDFTEFSRKCSEKWKTISKKEKKKYEALAKRDKDRYQREMRNYSGPRRERRRRDPDAPRKPPSSFLLFSQDHFDEIKEQHPNWTVAQVAKAAGRMWARCSEADKIPYEERAAVLRAKYLEEREAYYHQCQRGE", "length": 168 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2JW96-1", "protein_name": "Zinc finger protein 94 like 1", "gene_name": "Zfp94l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLPRGSCDVMLESLRNVASLGHRIGTPDGLLRLKREDMFWLLTVARWSSGSMGDKNLEDMEFLEEVGLRHLPHEELFCSQIWQRITRELTKVRDCRVRVGENGSPMKRDNREDEYSKHSSQNSVFQVHHRECHEEEANERDFGCSHHLRTSTGEKSYKCEKCHNASHWFSSLQSHQGVCDRPRWNKSVSQFKIFRQWPLFHYQQSMPNGENAQEYEACGNAGKNSSGQTALFVHTAEEPYSCEECGARFSQSSYLQVHQRVHTGEKPYKCEECGKGFGWLSQLHAHHQSHTGEKPYTCDACGKGFSYSSHLNIHCRIHTGEKPYQCEECGKGFSQASNLLAHQRGHTGEKPYQCDACGKGFSRISDFNIHIRVHTGEKPYKCEECGKGFSQASNLLAHQRGHTGEKPYKCNTCGKSFRRSSDLNVHCRIHTGEKPYRCEKCDKVFSQFSSLQVHQRVHTGEKPYQCSECGKGFSVGSQLQAHQRCHTGERPYQCEECGKGFCRASNFLAHHGVHTGEKPYRCDMCGKHFRQRSYLQAHHRVHTGEKQFRCEECGKGFSWSSYLQAHQRVHMGEKPYKCEECGKGFSWSSSLLTHQRVHAEDEGQKDLSSSGGSYRK", "length": 616 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2JYP5-1", "protein_name": "Olfactory receptor", "gene_name": "Or8g52b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPEGNHSRVTEFILTGLTDKPELQLPLFLLFLGIYLLTVLGNLGMIILILLSSHLQTPMYFFLSGLSFIDLGYSTVIIPKMLVNFVTEKNVISYPGCMTQLYCFIAFVLCECYMLSAMAFDRYVAICNPLRYNVTMSYQVCFWMIGGVYSIGFIEATIHTVCMLQVFFCKANVVNHFFCDLLPLFQLACSSTFVNETVLLCLSTLNFCVPTLTILSSYSFIIARIIRIKSTESRFKAFSTCSSHFSSVAVFFGSLGFVYFQPSSVSSKDQGKVSSVFYTIIVPMLNPLIYSLRNKDVKLALNKLFQKKIFHM", "length": 312 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K381-1", "protein_name": "Killer cell lectin-like receptor, subfamily A, member 4", "gene_name": "Klra4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSEQEVTYSTLRFHNSSGLQNQVKTNETQGPRETGHRGCSVSWHLIMIPLGILCSILLVTVAVLVTHIFQYSQEKHELQEALNKLHHNYSTMQNESYLNEEMLGNKSSECDAYKSVLDSLNRQQNTCLRLTNIVLDCLQHKGRQVNVHLFCCGIKCYYFIMDKKQWKECEQACQGCKLSLLTIDDEDELKFLQLQVTPDSYWIGLSYDNKKHDSAWIDNNPSKL", "length": 224 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K3S0-1", "protein_name": "Olfactory receptor", "gene_name": "Or4c109", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MYNQSFVNEFILLGLSQNPQIKKISFVIFLLVYIATLVGNMMIVVTIAYSPALLGSPMYFFLAVLSFLDACVSSVVTPKMIVDMVYERKSISFECCMTQVFAVHFLTAVEVIVLAAMAYDRYVAICKPLHYSSIMNRRLCGTLVGVAWAGGFLHSIIQIAFTLPLPFCGPNVIDHFICDLFPLLKLACTDTHIFIILVFANSGSICIIIFSFLLISYGVILFALRAHSSEGRRKALSTCGSHITVVVFFFVPCILIYARPTSAFSFEKNVFVFTDVLTPLLNPMVYTFRNKEMINAIRKMWKRLIVVSDKY", "length": 311 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K622-1", "protein_name": "Histone RNA hairpin-binding protein", "gene_name": "Slbpl", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSLSSRMEMVSVGVTTEPCHARWEVETDEVVLRRRQKQIDYGKCTPGYQSFLQQVPRAQRQPGFHPQTPNKNRRYSRRSWDAQIRQWRRALHTWDPPSQPLHDRQAEGKAAGNFLRPVDTAPLDDLLDNWPQDPESSENWDRGEKEAQFAYLKVPASCPPQLKDELLHH", "length": 169 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K698-1", "protein_name": "Lamin tail domain containing 1", "gene_name": "Lmntd1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSHLASSHRVQKSSLARPERRAKSPSYTDISFWVPVMHRVGSQYQFESVCEQSSGYPGMPAQQVTPVPSQRGGILRKEEKTGTITPSKQHSSVHFFPKVMDSSSTLHLLSGSFSHEASANFHQIPSAQDSLSPGGLLTSKSNVPSCSRKDSIPGKQSTHQAASPGTSLMTLKKQPKPSSDLDTYVLGDGEDYFLSLFGDSKKLTSHTSQAEDVSKHLSVILEEVGQFVSSSLGDIKIAEVNVKGFFVRLVNSSNEKEVEIGNYILQQNVNGQAVSLYRFPHNITMQASGTVTVWAAASEAKPQQPTDFVWEEQSRFRSSPDCTTILCKPSGEAIAWYTPIHWKQAWEKLETDIEFERCSVVIPSLKSHIFGRTTSSVSSINKEKQEPTQKTPPQVCSVLLREKEILLTVLPNKSPWCRSPDTPPHPYSSLIEWHDSDFPGSSLGTQPKPQSTKPKPDPGTKEKKSTR", "length": 467 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K6E6-1", "protein_name": "Rho GTPase-activating protein 20-like", "gene_name": "LOC120093152", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGEIHRTLLCQGPVELTSGRKRNKRYLSLFDDVLVVSTNLTKKKFKIKCIIPLNYLWVVDDEELVRANKTCTCKTIFFYWATGNALATFRSEEQKVQWYTFLTSRSISEAKKGIKKTFPLHIFPEDIQTCDSSLCVTATNMDTVNDIMEKLLPMIRVHKIEDYQLWFSPGHKEAPRALQGHEYPYDIIMNNVQNNLSKSNSKIFTAFPPLPGLFMENQSWDTGGQFILKPRDSAGSQQQDAKERRRKSCMTSCFHGGCVPHHDQECSDPRDDKRGKLFGQDLSSICQDGKLPTIILDMLSRIKDKGPTTDDIFLITPNGSLCKTIKEKLDNGENVDIYQQPVHVVAWILKEFLQSIKGSLLTSKLYDQWLIVPEKVNDKEKLAAVKSLLEKLPKPNADLLRQLFRILHQIKTKSSVNNMSSFRLSLETAPCILWLPSYRNNILTNDIAKKISLVTFMIDNSPELFGEDIVAVWYETSLYHPPGLKYPCSQNTPSSNGIMEETEHGLSSCPGERTCTPDFDELPRSGAVASIPYEGILASEKGEGNESTTQPEPVQNSPTPQTKKELGNCSPNILKDVNVPAVILDMLSVIAEKGQCSDDIFRMQAEKSHWSLKEKVNTGKHVNLKEESVLTVASVVKDFIKNIEGSLLSCDLYENWLSIPDEGPLLGKIASIQNILLKMPKPNYVLLKQLICVLQKIKAASTNQLDTFDLSVRIAPHVLWNPTCKMFYGRDLSKKLSIIQFMIDNCQELFGENDNIFCEDNQKSYDINLSSDTLNTSGKATLMIETIDDHDVKTSKANTKELEMSSAVPHEGGPTAGHNGTTSKYNVPQEIILHD", "length": 835 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K6V9-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "Smokwl2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDITSIKKTLGSQYRVVFFLGQGSYGRVRLAWHRRTQALVAIKTVEISKDTIRGILSEMTTLESLNHPNIISLYEVLITGTGVHFILQYAPGGNLGKLISEEGPLPEEKAKKMFGQVVSAIRYCHSLDIVHRDIKPQNILIDGEGNIKLIDFGQAIKCKPGTLLSRHCGTRDFNAPELVLREPYDGKSSDVWSLGVVLYFFTTGYLPFRGKTINDVEERITTGTYTIPTHLSGQLENLIHQILRVSPDMRPSVEEIENHPWIKKCEFKILPKTDPDYKIIEMLCAMGYKAKDILESLQKKRYDEPMGAYLSLKDHVSKGFDVGYITPAKPGDPCPPPPPSPAHPSVFGLPLRRRASEPIFGLHHRPPSREQNPLDLILSGLKMSRCVSMPPIAVYYPKKERSTSTRALHSTPVACPCVSNNMSEVEIILPPKQDIEMNTSSPPQRMGWFKRLRKGIRDCFSRLCCLPRAPKKKTQHRSSKRVAPLKKAASSTI", "length": 493 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K894-1", "protein_name": "Olfactory receptor", "gene_name": "Or4x6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAHLLNVTEFIFLGLSPNKEGQRVCFVLFLLLYMAIVLGNLLMVVTVAASRNLGSPMYFFLSFLSFVEICYSSTTAPKLIFDLLAEKKSISVWGCMTQLFFMHFFGGTEIFLLTMMAYDRYVAICKPLHYTSIMNQQVCAVLVGSAWIGGFVHSFSQILLILPLSFCGPNVIDHYFCDLLPVLKLACSDTFLIGLLIVVNGGTLSVISFVVLLASYLVILFHLRTQSAEGRRKALSTCGSHVTVVILFFGPCVFIYSRPSDTLPVDKMIAVFYTVITPLLNPLIYSLRNAEVKKAMKNLWFRIMKADEK", "length": 309 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2KB39-1", "protein_name": "Myb/SANT DNA binding domain containing 5 like 1", "gene_name": "Msantd5l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQREANQGESLENTEESNVGKSVKEEEQRPSGRSRSSWTDSEIRVFLQEWEVVEQEMGQPGRKLHKKTKSLCQRLYQQGLKKSWKSCFHLLLSLQDLHRTLCNERPGIEPLFSPYSEALYRILGSTPHESWFPGPLYDEADDSMLPVYPQPPMYQPSDYGITVPSAQLQGNPVPMMCQEDSPFPTWEPWNPSYPLSVPHLLPGFAPGDPSLQQPWSMCDLHQDPQ", "length": 225 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2KBC9-1", "protein_name": "Leukocyte immunoglobulin-like receptor subfamily B member 3-like", "gene_name": "Lilrb3l", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTFTFTALLCLGLTLRLWIPVLTGSLPKPILRVQPDSVVSMGTKVTFVCEETIGVKESHLYRNGNLQRTVLKNHQKPTNKTEFSFSNVDQQMQQYQCSYRTQTKSSDYSEPLELVVTGAYSKPSLSAQTNPVVTSGGYVTLKCEPSQDNHTLILTVEGSQKHSWRKDPECNRYTEKCHALFYVGPLTSNQRWIFRCYSYEKHTPQVWSAPSEPVELLVSGKLQKTTIKAEPGSVIRSGRAMTIWCQGDLDAEIYFLHKEGSHNTQSTQTLQQPGNKAKFLIPSVTQRHAGQYRCYCYSSAGWSEPSDTLELVVTGIYYYGVKLSGLPSPVVPEGGNVTLHCTSHSNYDKFILTKEDQKFTSSLDAEYIPSTGQHQALFVMGPMTPNYSGTFRCYGYYKHTPQLWSVPSELLKIFISGPSRKPSLLSHQGHILEPGMSLTLQCYSDTKYDKFALYKEGGTDIIESFSQWTKAGLSMTNFTLSVMPNSTVHSGENVTLMCWSTYSVDTFILSKEGSGQPPLRLKSKIQDQQYQSEFSMSGVTSKLSGTYRCYGSHDSSLYLKALIGVSVAFLLFLFILIFILLRRRHQEKFRKDDEDAQKGKELQLSTGAAEPVTRDRGHQKRSNPAAATQEESLYASVEDMETKDGVELDTWKPPEGDPQGETYAQVEPSRLRRAGAISPVVSREQLNTKYEQAEEGQEVDSQATESEEPQDVTYAQLCSRTLRQGTAAPPLSQAGEAPEEPSVYAALATARPGAVPKNKKQ", "length": 761 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2KIH5-1", "protein_name": "Major histocompatibility complex class I LLA precursor", "gene_name": "mhc1lla", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTGKVLFVLFLLSAPTTVLTDSHSLWLLGTYIKGETQFPKLSFTVMLDDLRVGFYNSETKEFIPRDNTTNEDEAVSDVLTVIQNTLEPFMMSTLTFKNGTESPQLFQITWHCELLDNDKPGQIIFKIAFSGSTTDEVSFYNDNFTCQCQNNMATVPLESFQMHYETVCYPNCIATIRDYLKKRQTQVNGKVQPKVRLIKKVHPKSGGFRLSCLATEFYPHSINLTLLRDGQPVSDHEVTGGNLLPNGDGTYQMRKSLEIRADEREKHKYTCSVSHLSLDKILDIDFEFDPSFLIKIVIPVVVLLSLMLVLTAVLIHKCKNKRAESKETITTASTPEPTEMSETLRK", "length": 346 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A0R4IEQ0-1", "protein_name": "Guanine nucleotide-binding protein subunit alpha", "gene_name": "gna11a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTLESMMACCMSEEAKESKRINAEIDKQLRRDKRDARRELKLLLLGESGKSTFIKQMRIIHGTGYTDEDKRGYTKLVYQNIFTSMQAMIRATEHLKIPFRFEDNKKNALLVREVDVEKVCSFEQPYVAAINKLWMDPGIQEAYDRRREYQLSDSTKYYLNDLERISSRGYMPTQQDVLRVRVPTTGIIEYPFDLENIIFSYLSDLERISDPSYLPTQQDVLRVRIPTTGIIEYPFDLQSIIFRMVDVGGQRSERRKWIHCFENVTSIMFLVALSEYDQVLVESDNENRMEESKALFRTIITYPWFQNSSVILFLNKKDLLEEKILCSHLVDYFPEFDGPQNDAQSAREFILKMFVDLNPDSDKIIYSHFTCATDTENIRFVFAAVKDTILQHNLKEYNLV", "length": 400 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A0R4ILG2-1", "protein_name": "FXYD domain-containing ion transport regulator", "gene_name": "fxyd2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGVESPEHSDADFTYDYELIRRGGLIFAAVLFCLGMVIIFSKKLRCGKSSATHEDNGDL", "length": 59 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A0R4IU63-1", "protein_name": "Metabotropic glutamate receptor 5", "gene_name": "grm1b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MRMLILRMNFFIVFLLFCTRLHLSTERSAVSRAASRSVARMDGDIIIGALFSVHHQPSAEKVAERKCGEIREQYGIQRVEAMFYTLDRINSDPYLLPNITLGCEIRDSCWHSSVALEQSIEFIRDSLISIRDEREGPKWCVEGNPSAQPPATKKPIAGVIGPGSSSVAIQVQNLLQLFNIPQIAYSATSIDLSDKTLYKYFLRVVPSDTLQARALLDIVKRYNWTYVSAVHTEGNYGESGMEAFKELASQEGLCIAHSDKIYSNAGEKHFDRLLRKLRERLPKARVVVCFCEGMTVRGLLMAMRRLGVAGEFLLIGSDGWADRDEVVEGYEEEAVGGITVKLQTEEVTSFNDYFLKLRLATNNRNPWFAEFWQHRFQCRLAGHPQENTNYRKNCSGYESLEDNYVQDSKMGFVINAIYAMAHGLHDMHEHLCPGHVGLCEEMDPIDGSKLLDFLLKTSFAGVSGEDVWFDENGDSPGRYDIMNLQYVEPGVFDYINVGSWHEGILSIDDYMIQMNRSEMVRSVCSEPCSKGEIKVIRKGEVSCCWICTPCKDNEYVQDEFTCKACELGWWPDEELQVCEPLPLRYLEWSHPESIAAVVFSCLGILVTSFVTLVFILYRDTPVVKSSSRELCYIILAGIFLGYICPFTLIARPSIASCYLQRLLVGLSASMCYSALVTKTNRIARILAGSKKKICTRKPRFMSAWAQVVIAFILISMQLTLEVTLIILEPPEPIKSYPSIREVFLICNTSNMGMVAPLGYNGLLILSCTYYAFKTRNVPANFNEAKYIAFTMYTTCIIWLAFVPIYFGSNYKIITTSFSVSLSVTVALGCMFTPKMYIIIAKPERNVRSAFTTSDVVRMHVGDGKIACRSNSLLNMFKRKKNASGNANSNGKSVSWSEPGSRHPPKGEHMWHRLSVHVKKQEAGSNQTAIIKPLTNTYNNPGMEFSDLSTKTLYNVAEEDEIDPIRYNPSNSPHLMAPVSKPMKEVGANLTFYTPEQHVPQQNSVLPQHAMIEHFQDDVVKYNSNMADLDEIISLPEPTDGIILALQPQVLHPHPILPMNVYQDEPSSPLEEVENEQFGLLHGYMYDNAQIHDEEELVQIKMAMEDSMALMPPSPFRDSLGSGSPVRNSPVSESVLCTPPSVTYASVILRDYKQSSSTL", "length": 1158 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A0R4IUN8-1", "protein_name": "Trypsin inhibitor ClTI-1-like precursor", "gene_name": "spink2.9", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLAQIVLLLCLSVMATAADKCPSVPNCSRYHPHACTMEYWPVCGSDGNTYGNECELCATIFEEKLNIILISKKGEC", "length": 76 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A0R4J2B9-1", "protein_name": "BTB domain containing 35, family member 23", "gene_name": "Btbd35f23", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEGIAGASYIPVSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFTNILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQKCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICNLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYNQEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A140T8Q5-1", "protein_name": "BTB domain containing 35, family member 21", "gene_name": "Btbd35f21", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDMKLMYLLALSSDLLVMQKEIDVYTTLKIWMILYLNPCWNGTMKQLLQHANNWLSTHMAYIDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYNEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1B0GQX3-1", "protein_name": "Cortexin domain containing 2", "gene_name": "Ctxnd2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MCVLMEDSSMSNGIDVDKGFAIAFVVLVFVFLIVMVFRCVKLVKNPYEVSSTTADLPLN", "length": 59 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1B0GRH6-1", "protein_name": "Zinc finger and SCAN domain containing 4, pseudogene 3", "gene_name": "Zscan4-ps3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASQQAPAKDLQTNNLEFTPTDSSGVQWAEDISNSPSAQLNFSPSNNGCWATQELQSLWKMFNSWLQPEKQTKEQMISQLVLEQFLLTGHCKDKYALTEKWKASGSDMRRFMESLTDECLKPPVMVHVSMQGQEALFSENMPLKEVIKLLKQQQYATRPTPDNEQMPVDTTQDRLLATGQENSENECNNSCNATEANVGESCSGNEMDSLLIIQKEQHPEHEEGNVVRQFPHGARRASQGTPSHHVDIQSPPTTADVTMEEQPKDLSRENISEDKNNCYNTSRNAATQVYSGDNIPRNKSDSLFINKRIYHPEPEVGDIPYGFPQDSTRASQGTSTCLQESLGECFSEKDPREVPGLQSRQEQLISDPVLLGKNHEANLPCKSHQKRFCRDAKLYKCEECSRMFKHARSLSSHQKTHLNKKSELLCVTCQKMFKRVSDRRTHEIIHMPEKPFKCSTCEKSFSHKTNLKSHEMIHTGEMPYVCSLCSRRFRQSSTYHRHLRNYHRSD", "length": 506 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1B0GS00-1", "protein_name": "Predicted gene, 36210", "gene_name": "Gm36210", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MHPGSPAAPGVSEPGPRELCAFVSGASAHMLRALQPRRIRPSKRRPNHRRFLHNQICREFAKIEAATQHLALTILSQKAPAQRPPFRRPPPPPPSPFLGVACAEAPMEAPHGSPSLSPVALDTSTLDLFDDILLTPTPRPLVTPDSFCQTLPAGNPQVASDVISHALGPGDQGQPTPIQAPRFSNLLLPPQKAQGGSLEPAALGCGWVDSWEAPYACDPQGVLDSWGAL", "length": 229 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1B0GSB3-1", "protein_name": "Family with sequence similarity 236, member D", "gene_name": "Fam236d", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIVMHLVGHPQLTGTEGVATEGVATAHTMLTSRGPRDTREPAPPTRSWRSRFQRALARVSKFFRRGRRTARG", "length": 72 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1B0GSI2-1", "protein_name": "Family with sequence similarity 236, member C", "gene_name": "Fam236c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIVMHLVGHPQLTGTEGVATAHTKENSSRGPRETREPAPCTRSWRSRFQRAVARVSKFFRRRRRST", "length": 66 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1C7CYU6-1", "protein_name": "Zinc finger and SCAN domain containing 4, pseudogene 2", "gene_name": "Zscan4-ps2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASQQAPAKDLQTNNLEFTPTDSSGVQWAEDISNSPSAQLNFSPSNNGCWATQELQSLWKMFNSWLQPEKQTKEQMISQLVLEQFLLTGHCKDKYALTEKWKASGSDMRRFMESLTDECLKPPVMVHVSMQGQEALFSENMPLKEVIKLLKQQQYATRPTPDNEQMPVDTTQDRLLATGQENSENECNNSCNATEGNVGESCSGNEMDSLLIIQKEQHPEHEEGNVVCQFPHGARRASQGTPSHHVDFPSVPTTADVPMEEQPKDLSRENISEDKNNCYNTSRNAATQVYSGDNIPRNKSDSLFINKRIYHPEPEVGDIPYGVPQDSTRASQGTSTCLQESLGECFSEKDPREVPGLQSRQEQLISDPVLLGKNHEANLPCESHQKRFCRDAKLYKCEECSRMFKHARSLSSHQRTHLNKKSELLCVTCQKMFKRVSDRRTHEIIHMPEKPFKCSTCEKSFSHKTNLKSHEMIHTGEMPYVCSLCSRRFRQSSTYHRHLRNYHRSD", "length": 506 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1C7CYV3-1", "protein_name": "Zinc finger and SCAN domain containing 4, pseudogene 1", "gene_name": "Zscan4-ps1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASQQAPAKDLQTNNLEFTPTDSSGVQWAEDISNSPSAQLNFSPSNNGCWAIQELQSLWKMFNSWLQPEKQTKEQMISQLVLEQFLLTGHCKDKYTLTEKWKASGSDMRRFMESLTDECLKPPVMVHVSMQGQEALFSENMPLKEVIKLLKQQQSATRPTPDNEQMPVDTTQDRLLATGQENSENECNTSCNATEGNVGERCGGNEMDSLLIIQKEQHPEHEEGNVVCRFPHGARRASQGNSSHHVDFRSALTPADVPMEEQPKDLSRENISEDKNNCYNTSRNAATQVYSSDNIPRKKTDSLSINKRIYHPEPEVGDIPYGVPHDSTRASQGTSTCLQESLGECFSEKDPREVPGLESRQEEPISDPVLLGKNHEANLPCESHHKRFRRDAKLYKCEECSRMFKHARSLSSHQRTHLNKKSELLCFTCQKMFKRVSDRRTHEIIHMPEKPFKCSTCEKSFSHKTNLKSHEMIHTGEMPYVCSLCSRRFRQSSTYHRHLRNYHRSD", "length": 506 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1D5P3Y4-1", "protein_name": "Large ribosomal subunit protein uL24m", "gene_name": "MRPL24", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MRLSALLRLAAPPKLPKGYRHGTWRPGTAAERLRNPPGQRRKKIFVEPISREDWKVFRGDTVQVLTGKDAGKQGMVTQVVRARNWVVVEGLNTHYRYVNRDAKYSSTYIASEAPLLLNQISLVDPEDRKPTEVDWRYTEEGERVRVSLRTGRIIPLPLWQRRDGIVPEQWIDGPKDTSVDDALDKTYTPSLKTFEEEIMDAMGIVETRRAKKSYWY", "length": 216 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A1D5PNZ8-1", "protein_name": "ODF3A protein", "gene_name": "LOC124417034", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MPASMDGAWVGTWRPHRPRGLISAQFPSPGPQYSIPGTTGYVGHSPTKARAPAYTFRGTKPPAAGSCGPGPCYFVEPAITRNGKYVAPGAQLRGRPATKTTVTPGPSDYRTEAANRHVFKCPPVQSMAFRREPLRTDHPPGPGTYTLPRLMGPNTVYTSASPCYSVRGRSQRGRFDEDLAKTPGPAALPKVPVDAYKTRAPAYTMAARPKAGEGKAAKPGPADYSVGRVTLIKPQAPASTFGIRHSLYTTPLIVE", "length": 255 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A1D5RLF0-1", "protein_name": "F-box and WD-40 domain protein 27", "gene_name": "Fbxw27", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "METHLPSLPLMKIFSYLDAYSLLQVAQVNKNWNALASSDVLWRKLCQKRWLFCDMVTLQLQDKETWKQFFVYRTWQEHSKTRANPRDFTYKEIPLQYGPCGYACYISGCGITRKGQDKSVVCMVNSKNTISTWDVHKSVITWVSPEQPASIKLLTTLPEMHIAVTVDIQSTIKLWDCHNREALATNILESPCKSLKAVITKDDPIVLVSDILGNLYIFRIPDLHLISTVNVLPCDIDEIYCSPQKKWVLLSKKQPYILPKVFYMSSLLRTSEFSAPVSTLLEISLCQEAFWTPRREDRLTLMSRSGCSKITKFETYDMKLEEFGNKIIVKGNSIAGFLLPYYTESLNWFGVSDKDTIVCSTEFSLLLFTNNGHRLQTFQYFSETIVRLSVDPVHVIVTCNDGSLDVYAWEERSLLLRKCYRLKNRRHLSPRGFINKTLCDDVSIIQLMIDGHDTWFLMAYALNICS", "length": 466 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1P8ASP4-1", "protein_name": "Serine/threonine-protein kinase PRP4 homolog", "gene_name": "PRP4KB", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MVSDKHVESNHRKHRRSFSPSDEVFKSPKRHKSRHHHRRHGHRHHRDEEVQYNDDENVNGGDLDMEEGEILGKEGIGETLKKKLESVDEFGDIKSGQFRENNLAFNGDDGFPLICKSWIRVYNYLSYKCHGRNQRRERECEKRKEIEPDRERRKERGSVDRDSRGDREKDYLRDRDNDRGRSRDKARYSSRERGRENERERRSEKDRDKGREFQSDREKHKSLDDGYGEVRHKHSGHSRHDAEDDLELRSPTSVNGHDPNSGDVKETRGNVERTRIDNDDKGDVVVWEVEQEDEELNLIEESRRRTQAIMEKYKKKLEQQNGFSSHDLELANIPKQSSTVADVLGSGTLGPVTSAVNQAKAGLDIDAVDGEVAKLSSAVGESPAQLVISDSDRTLASTGLGEGSPKDKISDDMFTDDIFGESPADSQKMVCTLTQIIDLVFIEFSNSGFICFVFPVHHLTRYSRNGLPFVHYIFVGYLRGKGNGIPIVRSGLDDNWDDAEGYYSYQLGELLDDRYEIMATHGKGVFSTVVRAKDTKAELGEPEEVAIKIIRNNETMHKAGQTEIQILKKLAGSDPENKRHCVRFLSTFKYRNHLCLVFESLHLNLREIVKKYGRNIGIQLSGVRVYATQLFISLKHLKNCGVLHCDIKPDNMLVNEGRNTLKLCDFGSAMFAGTNEVTPYLVSRFYRAPEIILGLPYDHPLDIWSVGCCLYELFSGKIMFPGSTNNEMLRLHMELKGAFPKKMLRKGAFIDQHFDKDLCFYATEEDSVTRKTTKRMMVNIKPKEFGSVIKQRYKDEDSKLLVHFRDLLDRIFILDPQKRITVSQALAHPFITGK", "length": 834 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "A0A1P8BFV1-1", "protein_name": "Bax inhibitor-1 family protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDGLKDFSRISPAIQSHLMRVYFSLFCILAASAFGAYLHMRLNIGGTITKLGWVLSLLEHVVSCPPYKHKIRFSLLLLFGVLHGASVGPCIKSTIDIDSSILITAFLGTAVIFFCFSAVAMLARRREYIYLGGLLSSGFSLLTWLKNSDQFASATVEIQMYLGLLLFVGCIVVNTQEIIEKAHCGDMDYAVHSLILYIGFVRVFLQILSIMWNTSADRIRRNNEET", "length": 226 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "A0A1W2P6Q8-1", "protein_name": "Cell division cycle 5-like protein", "gene_name": "Cdc5lrt6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPRIMIKGGVWRNTEDEILKAAVMKYGKNQWSRIASLLHRKSAKQCKARWYEWLDPSIKKTEWSREEEEKLLHLAKLMPTQWRTIAPIIGRTAAQCLEHYEFLLDRTAQRDNEEETTDDPRKLKPGEIDPNPETKPARPDPIDMDEDELEMLSEARARLANTQGKKAKRKAREKQLEEARRLAALQKRRELRAAGIEIQKKRKRKRGVDYNAEIPFEKKPALGFYDTSEENYQALDADFRKLRQQDLDGELRSEKEGRDRKTDKQRLKRKKESDLPSAILQTSGVSELTKKRSKLVLPAPQISDAELQEVVKVGQASEVARQTAEESGITNSASSTLLSEYNVTNNSIALRTPRTPAPQDRILQEAQNLMALTNVDTPLKGGLNTPLHESDFSGVTPQRQVVQTPNTVLSTPLRTPSNGAEGLTPRSGTTPKPVTNATPGRTPLRDKLNINPEDGMADYSDPSYVKQMERESREHLRLGFLGLPAPKNDFEIVLPENAEKELEEREIDDTYIEDAADVDARKQAIRDAERVKEVKRMHKAVQKDLPRPSEVNETILRPFNVEPPLTDLQKSEELIKKEMITMLHYDLLHHPYEPSGNKKGKNVGLATNDSEHITYLEHSPYEKFSKEDLKKAQGALVQEMEVVKQGMSHGELSSEAYNQVWEECYSQVLSLIAQSRYTRANLASKKDRIESLEKRLEINRGHMTTEAKRAAKMEKKMKILLGGYQSRAMGLMKQLNDLWDQIEQAHLELRTFEELKKREDSAIPRRLECLKEDVQLQQEREKELQQRYADLLMEKETLQAKF", "length": 802 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1W2P7S8-1", "protein_name": "Cell division cycle 5-like protein", "gene_name": "Cdc5lrt1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPRIMIKGGVWRNTEDEILKAAVMKYGKNQWSRIASLLHRKSAKQCKARWYEWLDPSIKKTEWSREEEEKLLHLAKLMPTQWRTIAPIIGRTAAQCLEHYEFLLDKTAQRDNEEETTDDPRKLKPGEIDPNPETKPARPDPIDMDEDELEMLSEARARLANTQGKKAKRKAREKQLEEARRLAALQKRRELRAAGIEIQKKRKRKRGVDYNAEIPFEKKPALGFYDTSEENYQALDADFRKMRQQDLDGELRSEKEGRDRKTDKQRLKRKKESDLPSAILQTSGVSEFTKKRSKLVLPAPQISDAELQEVVKVGQASEVARQTAEESGITNSASSTLLSEYNVTNNSIALRTPRTPAPQDRILQEAQNLMALTNVDTPLIGGLNTPLHESDFSGVTPQQQVVQTPNTVLSTPLRTPSNGAEGLTPRSGTTPKPVTNATPGRTPLRDKLHINPEDGMADHSDPSYVKQMERESREHLRLGFLGLPAPKNDFEIVLPENAEKELEEREIDDTYIEDAADVDARKQATRDAERVKEMKRMHKAVQKDLPRPSEVNETILRPFDVEPPLTDLQKSEELIKKEMITMLHYDLLHHPYEPSGNKKGKNVGFATNDSEHITYLEHSPYEKFSKEDLKKAQDALVQEMEVVKQGMSHGELSSEAYNQVWEECYSQVLYLPAQSCYTRANLASKKDRIESLEKRLEINRGHMTTEAKRAAKMEKKMKILLGGYQSRAMGLMKQLNDLWDQIEQAHLELRTFEELKKHEDSAIPRRLECLEEDVQRQQEREKELQQRYADLLMEKETLQAKF", "length": 802 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1W2P7Z8-1", "protein_name": "Cell division cycle 5-like protein", "gene_name": "Cdc5lrt7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPRIMIKGGVWRNTEDEILKAAVMKYGKNQWSRIASLLHRKSAKQCKARWYEWLDPSIKKTEWSREEEEKLLHLAKLMPTQWRTIAPIIGRTAAQCLEHYEFLLDRTAQRDNEEETTDDPRKLKPGEIDPNPETKPARPDPIDMDEDELEMLSEARARLANTQGKKAKRKAREKQLEEARRLAALQKRRELRAAGIEIQKKRKRKRGVDYNAEIPFEKKPALGFYDTSEENYQALDADFRKLRQQDLDGELRSEKEGRDRKTDKQRLKRKKESDLPSAILQTSGVSELTKKRSKLVLPAPQISDAELQEVVKVGQASEVARQTAEESGITNSASSTLLSEYNVTNNSIALRTPRTPAPQDRILQEAQNLMALTNVDTPLKGGLNTPLHESDFSGVTPQRQVVQTPNTVLSTPFRTPSNGAEGLTPRSGTTPKPVTNATPGRTPLRDKLNINPEDGMADYSDPSYVKQMERESREHLRLGFLGLPAPKNDFEIVLPENAEKELEEREIDDTYIEDAADVDARKQAIRDAERVKEVKRMHKAVQKDLPRPSEVNETILRPFNVEPPLTDLQKSEELIKKEMITMLHYDLLHHPYEPSGNKKGKNVGLATNDSEHITYLEHSPYEKFSKEDLKKAQGALVQEMEVVKQGMSHGELSSEAYNQVWEECYSQVLSLIAQSRYTRANLASKKDRIESLEKRLEINRGHMTTEAKRAAKMEKKMKILLGGYQSRAMGLMKQLNDLWDQIEQAHLELRTFEELKKREDSAIPRRLECLKEDVQLQQEREKELQQRYADLLMEKETLQAKF", "length": 802 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1W2P855-1", "protein_name": "Cell division cycle 5-like protein", "gene_name": "Cdc5lrt8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPRIMIKGGVWRNTEDEILKAAIMKYRKNQWSRIASLLHRKSAKQCKARWYEWLDPSIKKTEWSREEEEKLLHLAKLMPTQWRTIAPIIGRTAAQCLEHYEFLLDRTAQRDNEEETTDDPRKLKPGEIDPNPETKPARPDPIDMDEDELEMLSEARARLANTQGKKAKRKAREKQLEEARRLAALQKRRELRAAGIEIQKKRKRKRGVDYNAEIPFEKKPALGFYDTSEENYQALDADFRKLRQQDLDGELRSEKEGRDRKTDKQRLKRKKESDLPSAILQTSGVSELTKKRSKLVLPAPQISDAELQEVVKVGQASEVARQTAEESGITNSASSTLLSEYNVTNNSIALRTPRTPAPQDRILQEAQNLMALTNVDTPLKGGLNTPLHESDFSGVTPQRQVVQTPNTVLSTPLRTPSNGAEGLTPRSGTTPKPVTNATPGRTPLRDKLNINPEDGMADYSDPSYVKQMERESREHLRLGFLGLPAPKNDFEIVLPENAEKELEEREIDDTYIEDAADVDARKQAIRDAERVKEVKRMHKAVQKDLPRPSEVNETILRPFNVEPPLTDLQKSEELIKKEMITMLHYDLLHHPYEPSGNKKGKNVGLATNDSEHITYLEHSPYEKFSKEDLKKAQGALVQEMEVVKQGMSHGELSSEAYNQVWEECYSQVLSLIAQSRYTRANLASKKDRIESLEKRLEINRGHMTTEAKRAAKMEKKMKILLGGYQSRAMGLMKQLNDLWDQIEQAHLELRTFEELKKREDSAIPRRLECLKEDVQLQQEREKELQQRYADLLMEKETLQAKF", "length": 802 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1W2PP81-1", "protein_name": "TATA-box-binding protein-associated factor 11-like protein 5", "gene_name": "TAF11L5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METGRQTGVSAEMLAMPRGLKGSKKDGIPEDLDGNLEAPRDQEGELRSEDVMDLTEGDSEASASAPPAAKRRKTHTKGKKESKPTVDAEEAQRMTTLLSAMSEEQLSRYEVCRRSAFPRARVAGLMRAITGSSVSENAAIAMAGIAKLFVGEVVEEALDVCEMWGETPPLQPKHLREAVRRLKPKGLFPNSNCKRIMF", "length": 198 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A1Y7VLT7-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRRRGKNENESEKRELVFKEYGQEYAQVTKMLGCGWLEAMCFDGVRRLCHIRGKLRKKVWINTSDIILIGLRDYQDNKADVILKYNQDEARSLKAYGELPEHAKINEMDTFGPGDDDEIVFDDIGEDDEDIDDI", "length": 144 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1Y7VNG9-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad18", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRHRGKNENESEKRELVFKEYGQEYAQVTKMLGCLWLEAMCFDGVKRLCHIRGKLRKKVWISTSDIILIGLRDYQDNKADVILKYNPDEARSLKAYGELPEHAKINETDTFGPGDDDEIVFDDIGDDDEDIDDI", "length": 144 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A286YCH8-1", "protein_name": "Predicted gene, 47985", "gene_name": "Gm47985", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALGAELSETLVEKPEHMNLEMSILAPSKRKQLLDKKAEDKQPPESRGNNGRSSKSSPMGKDNTWPSPEAKVPSQKRSGQSWAVSSCGPHKRSSKLEDKRRNRPSRFRERGRDKPGSTHKRDSSHTKLHVKDRRSQPRSPVRTLKRSRSGDRQGAPHNSAKRHRQTSPPEASSLPTFSLLMSRVFTNVDALQVSLDDLQAPGGAFLRVPSSSTEPIVLQRAWLTWQLSHAGAALHWALHTVKSILTSQASLPRYTWPQGYSFTADPRPVPTSKIQASQLAQRPGDLASPNPSVDTRSILG", "length": 300 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A286YD13-1", "protein_name": "Predicted gene 8947", "gene_name": "Gm8947", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALGAELSETLVEKPEHMNLEMSILAPSKREQLLDKKAEDKQPPESRCNNGRSSKSSPMGKENTWPSREAKVPSQKRSGQSWAVSSCGPHKRSSKLEDKRRNRPSRFRERGRDKPGSTHKRDSSHTKLHVKDQRSQPRSPVRTLKRSRSGDRQGAPHNYAKRRRQTFPPEASCSLPTFSLLMSRVFTNVDALQVSLDDLQAPGGAFLRVPSSSTEPSVSQRAWLTWQLSHAGAALHWALHTVNSILTAQASLPRYIWPQGYSFTADPRPVPTSKIQASQLAQRPGDLASPNPSVDTRSILG", "length": 301 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A286YE43-1", "protein_name": "Predicted gene, 47996", "gene_name": "Gm47996", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALGAELSETLVEKPEHMNLEMSILAPSKRKQLLDKKAEDKQPPESRGNNGRSSKSSPMGKDNTWPSPEAKVPSQKRSGQSWAVSSCGPHKRSSKLEDKRRNRPSRFRERGRDKPGSTHKRDSSHTKLHVKDRRSQPRSPVRTLKRSRSGDRQGVPHNSAKRCRQTSPPEASSLPTFSLLMSRVFTNVDALQVSLDDLQAPGGAFLRVPSSSTEPSVSQRAWLTWQLSHAGAALHWALHTVNSILTAQASLPRYTWPQGYSFTADPRPVPTSKIQASQLAQRPGDLASPNPSVDTRSILG", "length": 300 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A286ZIN6-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "LOC110258935", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MANLTSMSGFLLMGFSDDHKLQILHALLFLVIYLLALTGHLLIITITTLDHHLHSPMYYFLKHLSLLDLCFISVTVPQSIANSLMNNGYISLGQCILQVFFFIALASSEVAILTVMSYDRYVATCQPLQYETIMDPWACRQAVIAVWVTGGLSGLTHTAINLSVPLCGDRVIHQFFCDVPQMLKLACSYEFINEIAVAAFTTSTAFFCLISILLSYTRIFSAVLRIPSAQGRTKVFSTCLPHLLVVTFFLSAAGFEFLRPPSDSQSAMDFMFSIFYTVVPLTLNPVIYSLRNKAMKAALRKVLSKEEFAQRKKYFKALFQL", "length": 321 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZIP8-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110259124", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "QEYKANGGDNTTTIIHFVLLGFSDFPHIRPALFVVFLVIYILTLTWNLCLIVLIRLDSHLHTPMYFFLSNLSFIDICYVSSTAPKMLYDFFQAKPTITVVGCAIQYFVCSTMGLSECCLMTVMAYDRYAAICNPLLYSSIMSPSLCGRMVLGSYMAGLSATLSQVCAVLQLHFCGPNVIHHFFCDMPLMLGLSCSDTFFVQVLTAIFTVFFGIINALVIMMSYVYIVISVMKITSAKGRSKAFNTCASHLTAVTLFYTSGIFVYLSSSSGGSSGLDRFAAVFYTVVIPMLNPLIYSLRNKDIKDALKRLKKRKECC", "length": 316 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZLI4-1", "protein_name": "C-C motif chemokine ligand 24", "gene_name": "CCL24", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MFSPSSLIKASGQLQCPAGNRLLAPTLSSCIAALSPELPLLLSRHGRPVTVAASLLFLGLCAYSFAPADSVTMPSSCCIYFISKKIPESRVASYQLSNSSVCPQAGVIFTTRKGQKFCGDPKQLWVQKYMKKLDAKRKKASTRIRAMGTGAPVRRGPANSTSI", "length": 163 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZSE3-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258059", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRNRTITTFILLGLTDDPKLQVLIFIFLFVAYMLSLTGNLTIITLTFVDSHLKTPMYFFLKNFSFLEISFISSCIPRYLYSIATGDKVITYNACVIQVCFTDLCGVTEFFLLAAMSYDRYVAICKPLHYVTIMSSRVCGILISSCWMAGLCVLIPPLSLGLNLKFCDSNRLDHFGCDAFPLVKISCSDTWPMEQTVIICAVLTLNMTLTCVVLSYAYIIKTIFRFPSVQQRKKAFSTCSSHMIVVSITYGTCIFIYMNPTAKGEVTIKKVVSLLIFSVSPTLNPFIYTLRNNQVKRAFKDSIKRIALLSTR", "length": 311 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZU87-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "LOC100152920", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEGENQTVLFEFIILGFSNLKELQFLLFTIFLVTYICTLGGNSFIILETMTNLHLHTPMYFFLENLAFLDICYTTTNVPQMMAHLLSEKKSISYLGCMAQLFAFIFFVGSESLLLAAMAYDHYIAICKPLRYSVIMNKVLYSQLAASCWSGGFLNSTVHTVLTFRLPFCGNNQINYFFCDIPPLLVLSCGDTSVNELALLSIGVVIGWTPFLCIVLSYLYIISTILRIRSSKGRQKAFSTCASHLTIVLLYYGSAIFTYGRPISTYSLEKDRLISVLYSIVTPMLNPIIYSWRNKDIQEAMQVMGRKWKASSSLSFDV", "length": 318 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZVC9-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258401", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGQRNSTSLHDFILLGFSDHPKLEMALSGVVATFYLITLVGNTAIILASLLDSHLHTPMYFFLRNLSFLDLCFTTSIVPQMLVNLWGPHKTISYGGCVIQLYVYMWLGSIECLLLAVMSYDRFTAICKPLHYLVIMNPHLCLKMIIMVWSISLANSVVLCTLTLNLPRCGNNLLDHFLCELPAMLKIACIDTTAVELSVFALGIAIVLTPLILILISYGYIAKAVLRMKSRAGQRKAINTCGSHLTVVSIFYGAIIYMYLQPGNNASRGQVIFLTLFYTIITPSLNPLIYTLRNKDMKEALKKLMRVDHKSTKSKRTWKS", "length": 320 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZWC4-1", "protein_name": "Zinc finger protein 16", "gene_name": "ZNF16", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLPLSQVPAMPSLRTRPGKAEMEPSVPGPSLRTPGTQVSVSDAPAVTHPGSALHGPLSCGDTEPGATPPHHQLADWDLRTEGSQLLQKEDASEDLESQAGTSEDYVGAGSQAPERGELCADVLGSDWGVPQGERLSLCQEGGFMPAYLLPGSPLEEPEIDTEPLERNFGLIITPVASPGEPEEETPQPFDACDQSVHCGVDLAGHEGLHAAESSFICGECGESVGLHSDLLRHRLSHRGEKPHVCAECGEAFSQSASLESHQRSHEPAKPFQCSTCGKAFGRSSSLIKHHKVHTRERPHACGECGRPFSRFSNLVKHRRVHTGEKPYRCSECGKAFSQSSSLLQHRRVHTGEKPHVCPVCGKAFSYSSVLRKHQIIHTGVKPYSCSACGKAFSHSSALIQHQGVHSGDKPYECRECGKTFGRSSNLILHQRVHTGEKPYECAECGKTFSQSSTLIQHQRIHNGLKPHECDQCGKAFNRSSNLIHHQKVHTGEKPYTCVECGKGFSQSSHLIQHQIIHTGERPYKCGECGKAFSQRSVLTQHQRVHTGEKPYDCEACGKAFSQRSKLVKHQLIHARE", "length": 576 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZX75-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100156955", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "IFIMEWENQTASSDFILMGIFSHTPTHIFLFSLVLGIFTVALLANTVMVLLICLDRRLHTPMYFLLSQLSLMDLMLICTTVPKMARNYLSGRKSISVAGCETQIFFSVSLFGAECFLLAVMAYDRYAAICYPLQYPQLMNWNVCGLLAASSWILGVFDGIVDIAATLSFSYCGSREIPQFFCDITALLRLSCTDTSTFETLVFICCVVMLLFPLSLIIISYTRVIITVIRMSSGEGRHKAFTTCSSHLVVVGMYYGAAMFIYMRPTSNRSPAQDKMVSAFYTILTPMLNPLIYSLRNKDVAKAFSRCWGREI", "length": 312 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZY56-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258501", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "METDNDTQILEFLLLGFSKQPESQPIIFGLFCSMYLITVFGNLLIILAVISDYHLHIPMYFFLSKLSFVDICFTSTTIPKMLWNIQTQSKAITYEGCITQIYFLILFAVLDILLLTVMAYDRFVAICHPLHYTVIMNPRLCGLLVLVPWIMSVLNSLLQTLMMMQLSFCTNFEIPHFFCELNQMIQLACSDTFLNTIVMYFAAALLCGGPFFGILCSYSKIVSSIYRISSAQGKYKAFSTCASHLSVVSLFYCTMLGVYLSSAAAHSSHSSATASVMYTVITPMLNPFIYSLRNKDMKRALKALFVKGPM", "length": 310 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZZP6-1", "protein_name": "HSF-type DNA-binding domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MANAPSEIQGVSPKDESTGSESSITSPWCDNSITGDLDLRSQIEEKAFQALSEGSLMKEPCHTLCASEPDGDNDFPPLPFPRKLWEIVESDRFKSIWWDENGTSIVINEERFKKEVLERKAPFRIFETESMKSLVRQLNLYGFTKLRRNFQRPASLANILAEDNEVSAWNKLQFYHNPNFKRGCPHLLVRMKRRVRVKNASPVSASVLQGCSKKRSRTGGDVDNHNSDVAAETRGEDAFSASTNLNVPLIRWPSMSQRISNTTTPTRSGLSSPSSPSFRPPGQIAMAQHAIFSQLTTFHMHSQSSYSPASGHIVNFITTTTSISQYRCISYFPSGYFGLRVEPSPLPTRYQNISPTEGPVSNPQPAAHPWFPMPMATDTSAASLSRPNPQSSSVSEHLPNYH", "length": 402 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287A7E2-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258743", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGQRNSTSLHDFILLGFSDHPKLEMALSGVVATFYLITLVGNTAIILASLLDSHLHTPMYFFLRNLSFPDLCFTTSIVPQMLVNLWGPHKTISYGGCVIQLYVYMWLGSIECLLLAVMSYDRFTAICKPLHYLVIMNPHLCLKMIIMVWSISLANSVVLCTLTLNLPRCGNNLLDHFLCELPAMLKVACIDTTAVELSVFALGIAIVLTPLILILISYGYIAKAVLRMKSRAGQRKAINTCGSHLTVVSIFYGAIIYMYLQPGNNASRGQVIFLTLFYTIITPSLNPLIYTLRNKDMKEALKKLMRVDHKSTKSKRTWKS", "length": 320 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287A7J9-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258750", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEQNNGTEVKEFILLGFAGQHKSWLVLFIVFLGIYVVTLVGNIGMILLIKIEASLHTPMYFFLQNLAFVDLCYATAITPKVLQNLMSTEKSISFIGCMVQLFVYGTFVTSDGYILAAMAVDRYVAICNPLRYPTVMSQRVCIQLLIGSCFMGFLNACVNGSLTFQLNFCKSNKINHFFCDAPPILALSCSSIYFNIMLLAAFVGFNLMFTVSIIIFSYIFILAAILKISSAAGRKKAFSTCGSHLTAVTIFHGTLSYMYLHHRTLESQEQEKLASVFYGIVIPMLNPLIYSLRNQDVREALKEIGKKML", "length": 309 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287A951-1", "protein_name": "Small ribosomal subunit protein uS8", "gene_name": "LOC100514137", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVHMNVLTDALESINNSEKRGKRQVLTRLCFKVIVRFLTVMMKHGTPIGKFEIMDDPRARKIVVNLTGRLNKCGVISPRFDGQLKDLEKWQNKLLPSCQFGFIVLTTSAGIMHHEEAR", "length": 118 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287ACV2-1", "protein_name": "HSF-type DNA-binding domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAHAPSEIQGVSPKDAPTGSESSITSPWCDNSITGDLDLRSQIEEKAFQALSEGSLIKEPCHTLCASEPDGDNDFPPLPFPRKLWEIVESDRFKSIWWDENGTSIVINEERFKKEVLERKAPFRIFETESMKSLVRQLNLYGFTKLRRNFQRPASLANILAEDNEDSAWNKLQFYHNPNFKRGCPNLLVRMKRRVRVKNASPVSASLLQGCSKKRSRTGGDVDNHNSDVAAETRGEDAFSTSTNLNVPLIRWPSMSQRISNTTTPTRSGLSSPSSPSVRPPGQIVMAQHAIFSQLTTFHMHSQSSYSPASGHIVNFITTTTSISQYHRISNFPSGYFGLRVEPSPLPTRYQNISPTEGPVSNPQPAAHPWFPMPMATDTSVASLSRPNPQSSSISEHHPNYY", "length": 402 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AEV7-1", "protein_name": "Uncharacterized protein", "gene_name": "WFDC10AL", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MKWWGLQWLMLSCLAILPASGNWQERISASLEALTQSKLIPGMKPCKTIPTKEQCTYFCDLPRACPTGLLCCSASCGNVCMPPKGHGNRRSSHKISNFLFTAEPIKQQ", "length": 108 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AF12-1", "protein_name": "Large ribosomal subunit protein eL21", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTNTKGKRRGTRSMSSSPFRKHGVVPLATYMRIYKKGDIVDIKGMGTAQKGMPHKCYHGKTGRVYNVTQHAVGTVVNKQVKGTILAKRINVHIVHIKHSKRGDNFLKRVKENDQKKKEAKEKVTWVQLKHQTAPAREAHFVRTNGKEPELLEPNP", "length": 155 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AGK9-1", "protein_name": "DM domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDPDEMPTVPCCPLDSTTGLETGAPWGIEFGPRRAIRRCARCHNHGITDQIKDQEHLCLFQACECHKCVLFSEHCSILPAESALKTMQELHLKRQLTQGLIKSGTTSPKAHSHVKKSSIQTGVLSKLPRCSADRSGIGIFVSVLDSSTLEEATNNFTFQEVTQAPCPAQQAPKTSDQDSDSASLEWQRKLEAAEALLTLRESSQAPSGPTPLLQPSAAPAPAGERGLQPPSRSLRPRPASSISLPIGHVGCISLLS", "length": 256 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AKK8-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "LOC100155397", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDVRNHSIVSEFVFLGFTNSWEIQLLLFVFSFLFYSSSMMGNLVIVFTVTLDSHLHSPMYFLLANLPAIDMVFCSITAPKMIGNIFKKHKAISFCGCITQIFFTHAAGGTEMVLLIAMAFDRYVAKCRPHHYLTIINPRICLCFLVTSWIIGLIHSMAQLFFVVDLPFCDLNVLDSFYCDLPRLLRLACTDTQELQFMVTVNSGLLSMGSFVLLIISYIFILFTIWKHASGGSSKALSTLSAHITMVVLYFGPLIFFYTWPSPTSHLDKYLAIFDAFITPFLNPVIYTLRNKEMKVAMRRLFSHLVHYRNIS", "length": 312 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AP00-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258730", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "SRHDLHCSLWQDNSMSVKRFAFARFSEVTEQCFLLFTLILLMFLASLTGNALIATAIWTNPVLHTPMYFFLANLSLLEIGYTCSVIPKMLQSLVSEARGISREGCATQMFFFAFFGISECCLLAAMAFDRYMAICSPLHYATRMSRGVCDHLAMVSWGVGCMAALGQTNYIFSLDFCGPCEIDHFFCDLPPILALACGDTSHNEAAVFVAATLCISSPFLLIIASYGRILAAVLSMPSPEGRRKALSTCSSHLLVVTLFYGSASVTYLRPKASHSPGIDKLLALSYTVVTSMLNPIIYSLRNKDVKAALRRTLGKKKVLAHR", "length": 322 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287ARD5-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258934", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDGKNQTALSEFIILGFSNLNQLQFLLFTIFFLTYICTLGGNTFIILVTVVDPRLHTPMYHFLGNLAFLDICYTTTNVPQMMAHLLSEKKSISYGGCMAQLFAFIFFVGSECLLLAAMAYDRYIAICKPLRYSVIMNKVLYSQLAASCWSGGFLNSAVHTVLTFRLPFCGNNQINYFFCDIPPLLVLSCGDTSVNELALLSIGVVIGWTPFLCIVLSYLYIISTILRIRSSKGRQKAFSTCASHLTIVLFYYGSAIFTYVRPISSYSLEKDRLISVLYSVVTPMLNPIIYTLRNKDIKEAMKAVGRKWQLPLLSFDV", "length": 317 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AT12-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLSFNRTGVSHTVFYLLGIPGLEDQHLWISIPFFISYVTALLGNSLLIFLILTRRSLHEPMFLFLCMLAGADLVLSTCTVPQALAIFWFRAGEISLDRCITQFFIIHCIFMSESGILLVMAFDRYVAICYPLRYTTILTHTLIGKIGVTIFLRSYCTVFPIIFLLKRLTFCRNNVLPHTGCEHIGLAKYACNDIRVNIWYGLFVIVSTLFLDILLIFVSYMLILRAVFHMPSQDARHKALSTCGSHVCIIILFYGPGILTTLAQRFGRHIPAHIHILLANVCVLAPPMLNPIIYGIKTKQIQEQVAHLFLKQK", "length": 313 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AUC4-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MERINKSHPEEFILLGFADRPWLELPLFIILPMYFFLTNLSFLDMCYTTSIVPQMLFHLGGSEKTISYLGCAVQLYFFHTMGGTECLLLALMSFDHYVAICKPLHYTLIMNRCTCILLVATVWLSGMTYAVSEATVTLHLPLCGHNTLDHLICEIPVLIKAPCGEKGTNELTLSVVCIFMLAVPLCFILASYASIGHAVFKIKSSEGRKKAFGTCSSHLIVVFFFYGPDISMYLQPPSSISRDLPKFMALFHGVVTPTLNPFIYTLRNKDVKGAWGNLVRSVFTSK", "length": 286 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AXC2-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEQNNGTEVNEFILLGFAGQHKSWLVLFIVFLGIYVVTLVGNIGMILLIKIEMLQNFVGTEQSISFIGCMVQLLIYGAFVTSDCYILAAMAVDRYVAICNPLRYPTVMSQRVCIQLLIGSYLIGFLNASVHVSFILPLNFCKSNKINHFFCDAPPILALSCSSIYFNVMLLAAFVGFNLTCTVLVVIFSYIFILAAILKISSAAGRKKAFSTCASHLTAVTLFYGTLSYMYLHHRTLESQEQEKLASVFYGIVIPMFNPLIYSLRNQDVREALKGVGKQCF", "length": 281 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AY25-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100155405", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAHTNESVVLEFVLLGLTNSWELQLFLFAIFSIVYVTSVLGNTMIIVIIASDSRLNSPMYFLLSNLSFIDICQSNFATPKMLVDFLVEHKTISFEGCMAQIFLLHSFVGSEMMLLVAMAYDRFIAICKPLHYSTIMSRRLCIIFVFISWAVGILHSVSHLAFTVDLPFCGPNEVDRFFCNLPLVIELACMDTYKVEILTLTNSGLISLGCFLALIISYTVILITVHRWSSSGSSKALSTLTAHITVVILFFGPCIYFYIWPFSRLSVDKFLSVFYTVCTPLLNPIIYSLRNEDVQSAMHKWRNHHVNSWKY", "length": 311 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287B1Z6-1", "protein_name": "Short stature homeobox", "gene_name": "SHOX", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEELTAFVSKSFDQKSKESSGGGGGGGGKKDSITYREVLESGLARSRELGGSDSNLQDITEGSGHCPVHLFKDHVDNDKDKLKEFGTGRAAEGIYDCKDKREDVKSEDEDGQTKLKQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCRKQENQMHKGVILGTASHLDACRVAPYVNMGALRMPFQQVQAQLQLEGVAHAHPHLHPHLAAHAPYLMFPPPPFGLPIASLAESASAAAVVAAAAKSNSKNSSIADLRLKARKHAEALGL", "length": 292 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287B9C9-1", "protein_name": "HSF-type DNA-binding domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAHAPSEIQGVSPKDESTGSESSITSPWCDNSITGDLDLRSQIEEKAFQALSEGSLMKEPCHTLCASEPDGDNDFPPLPFPRKLWEIVESDRFKSIWWDENGTSIVINEERFKKEVLERKAPFRIFETESMKSLVRQLNLYGFTKLRRNFQRPASLANILAEDNEVSAWNKLQFYHNPNFKRGCPHLLVRMKRRVRVKNASPVSASVLQGCSKKRSRTGGDVDNHNSDVAAETRGEDAFSASTNLNVPLIRWRSMSQRISNTTTPTRSGLSSPSSPSFRPPGQIAMAQHAIFSQLTTFHMHSQSSYSPASGHIVNFITTTTSISQYRCISYFPSGYFGLRVEPSPLPTRYQNISPTECPVSNPQPAAHPWFPMPMATDTSAASLSRPNPQSSSVSEHHPNYH", "length": 402 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BB76-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100157512", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAHTNESVVLEFVLLGLTNSWELQLFLFAIFSIVYVTSVLGNTMIIVIIASDSRLNSPMYFLLGNLSFIDICQSNFATPKMLVDFLVEHKTISFEGCMAQIFLLHSFVGSEMMLLVAMAYDRFIAICKPLHYSTIMSHRLCIIFVFISWAVGILHSVSHLAFTVDLPFCGPNEVDSFFCDLPLVIELACMDTYKIEILTLTNSGLISLGCFLALIISYTVILITVHRWSSSGSSKALSTLTAHITVVILFFGPCIYFYIWPFSRHSVDKFLSVFYTVCTPLLNPIIYSLRNEDVQSAMHKWRNRHVNSWKY", "length": 311 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BC21-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100152520", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDGKNQTALSEFIILGFSNLNQLQFLLFTIFFLTYICTLGGNTFIILVTVVDPRLHTPMYHFLGNLAFLDICYTTTNVPQMMAHLLSEKKSISYGGCMAQLFAFIFFVGSECLLLAAMAYDRYVAICKPLRYSVIMNKVLYSQLAASCWSGGFLNSAVHTVLAFRLPFCGNNQINYFFCDIPPLLVLSCGDTSVNELALLSIGVVIGWTPFLCIVLSYLYIISTILRIRSSKGRQKAFSTCASHLTIVLLYYGSAIFTYVRPISSYSLEKDRLISVLYSVVTPMLNPIIYTLRNKDIKEAMKAVGRKWQLPLLSFDV", "length": 317 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BF45-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100513333", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRNRTITTFILLGLTDDPELQVLIFIFLFLAYMLSLTGNLTIITLTFVDSHLKTPMYFFLKNFSFLEVSFISSCIPRYLYSIATGDKIITYNACFIQVCFTDLCGITEFFLLAAMSYDRYVAICKPLHYVTIMSSRVCGILISSCWMAGLCVLIPPLSLGLNLKFCDSNRLDHFGCDAFPLVKISCSDTWPMEQTVIICAVLTLNMTLTCVVLSYAYIIKTIFRFPSDQQRKKAFSTCSSHMIVVSITYGTCIFIYMNPTAKGEVTIKKVVSLLIFSVSPTLNPFIYTLRNNQVKRAFKDSIKRIALLSTR", "length": 311 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BGE2-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MENNQSWIAEFILVGFQLSEEMELFFFIIFFLLYIFNLLANGMILGLICLDPRLHSPMYYFLTHLAVTDISYASSNLPNMLENLVKHKKTIPFVSCTLQMLFYLAFASVECLILVVMSYDRYVAICHPLQYTVIMNWKLCTVLAIISWACGFFLALVQVSLFLRLPFCGPQKVNHFFCEIRSVLKVTCGETWINKIFLFADGVFILVTPISLMLVSYVRILWAILKIQSKEGRKKAFSTCSSHLCVVGFYFGIAMMVYLVPDDSHQQEEQQKILFLFYTFFNPLLNPLVYSLRNAQVKAAFHRIFQKNRTM", "length": 311 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BIM6-1", "protein_name": "Histone H2A", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPGKRSRRKSPGRQGRTCARTTRAGLSASVSHMERLLREGPYAQCLSSSARVFLAATIEYLTARVLELAGDEAQIVGRRCITPELVAMAVHNNALLSAFFGTLAISQVAPTQE", "length": 113 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BK27-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVTEFIFLGLSNSQELQTFLFVFFLVFYVGIVFGNLLIVLTVMIADFFRKCKVISFKGCLAQIFLLHFFGGSELVILIAMAFDRYVAICKPLRYTTIMSSNVCVGIVAAAWGTGFLHSVSQLAFAVNLTFCGPNEVDSFYCDLPRVIKLSCTDTYRLDIMVIANSGVLTVCSFVLLIISYTVILVTIQHLPSQKSSKALSTLTAHITVVLLFFGPCIFIYAWPFPIKSLDKFLAVFYSVVTPLLNPIIYTLRNKDMKTAMKRLRKWNMNSRIKP", "length": 274 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BKA6-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110259008", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTFNCSLWQDNSMSVKRFAFARFSEVTEQCFLLFTLILLMFLASLMGNALIATAIWTNPVLHTPMYFFLANLSLLEIGYTCSVIPKMLQSLVSEARGISREGCATQMFFFAFFGISECCLLAAMAFDRYMAICSPLHYATRMSRGVCVHLAMVSWGVGCMVGLGQTNYIFSLDFCGPCEIDHFFCDLPPILALACGDTSHNEAAVFVAATLCISSPFLLIIASYGRILAAVLSIPSPEGRRKALSTCSSHLLVVTLFYGSASVTYLRPKASHSPGIDKLLALSYTMVTSMLNPIIYSLRNKEVKVALRRTVGKKKVLAHR", "length": 320 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BKW4-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258932", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEGENQTVLFEFIILGFSNLKELQFLLFTIFLVTYICTLGGNSFIILVTMTNLHLHTPMYFFLENLAFLDICYTTTNVPQMMAHLLSEKKSISYLGCMAQLFAFIFFVGSESLLLAAMAYDRYIAICKPLRYSVIMNKVLYSQLAASCWSGGFLNSAVHTVLAFRLPFCGNNQINYFFCDIPPLLVLSCGDTSVNELALLSIGVVIGWTPFLCIVLSYLYIISTILRIRSSKGRQKAFSTCASHLTIVLLYYGSTIFTYGRPISTYSLEKDRLISVLYSIVTPMLNPIIYSLRNKDIQEAMQVMGRKWKASSSLSFDV", "length": 318 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BLZ6-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "LOC110258167", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAGGKNSTTITKFILLGFSEFPKLTAVLFSVFLRISLMTVSWNMGLIMLIRMDSHLHTPMYFFLSNLSLLDICYVSTIAPRMLSDFFKKYKFISFMGCTMQYFFSSLALTECCLLAAMAYDHYAAICNPLLYTAIMSPTLCVQMVAGSCVTGFFGSFIQLCALFQLHFCGQNVTNHFFCDLPQLLILSCSDTFFFQVMTSVLTVIFGLTSVLVIIISYGYIIATILKITSSEGRSKAFNTRASHLTAVTLFFGSGIFIYMYPNSGDSLSQNKLVSVLYTVIISMLDPLIYSLRNKEIQDSLSRWRKTIFSWCY", "length": 313 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BNL4-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "TVLNARNVSTPKVFILLGFSDHPWLEMPLFIIVLAAYIRTLVGNISIIVVSRVDPNLDSPMYFFLSNLSFLDLCFTTTTIPQLLLNLWGPDKSISYGGCVTQFYMFHFWGATECIFLAVMSMDLQAICKPLRYPVIMHQQLCIFLVVMAWLSGLVNSLLQSSLTIQLPLCGNNKVDDFLCEVPVMIKMSCTDTTFNVAMLSIVGTFYSLVPLSLILVSYGFIVATVLRIQSSEGKKKAFNTCSSHTIAVSLFYGPVISMYVQPSAANSQDKNKLMSLFYSLVTPMLNPFIYTLRNKDMKGAMMRLLVSLYHQRRG", "length": 315 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BSD4-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100525471", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MENENSTVVAEFIFVGLTQSRNIQLLVFVLILIFYLIILPGNFLIILTIRSDPGLTAPLYFFLGNLAFLDASYSFIVAPRMLVDFLSEKKVISYRGCITQLFFLHFLGGGEMLLLVVMALDRYIAICRPLHYSTVMNLRACYALLVALWLGGFVHSIIQVALILHLPFCGPNRLDNFFCDVPQVIKLACTDTFVVELLMVFNSGLMTLLCFLGLLASYAVILCRVRGSSSEGKTKAMSTCTTHIIVIFLMFGPAIFIYTRPFRAFPADKVVSLFHTVIFPLLNPVIYTLRNQEVKTSLKRLLNQQLA", "length": 307 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A2R8VHJ9-1", "protein_name": "Predicted gene, 36245", "gene_name": "Gm36245", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSTKNEEQNEDQSEGVVIPHIQDHHCLAILAFCFFFPLGYLAYRSSCKTRTYIEQKEYEKAKATSRCTFAFVLSSIAGGSIIFFCLFSRLFFM", "length": 93 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A3L7ICH5-1", "protein_name": "Cytochrome c oxidase subunit 7A2-like, mitochondrial", "gene_name": "LOC100756118", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MYYKFSGFTHKLAGAWALESYSPQGLKPVASTEAPPIVFATPTKLTSSVTAYVYAGKNKVPELQKFFQNFFHLKRGLPDQMLYRTPMALTVGGTIYCLSALYMASQTPNK", "length": 110 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A3Q1LL21-1", "protein_name": "BTB domain-containing protein", "gene_name": "LOC112445444", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGPLNSRNLQCRESGTGELQQPEAQAGPSYVSGSRKRKQSTGPSLGPESEMSHNQEEDLQQVVCTRQGKKVKIKSEYAYQTLFLNGETSDIKIRALGKVWCLHKRFLCQSDYFATMFRDSGKECHKDIIDLEINDQNINVESLQFVLGSLYRNEYVLIKPLQVPRVLATACLLQVEDLIQQCDKTMKETINVKTVCSFYVAAETYGLHSVKTGCFEWLLHNLMTHPSVELYKKLSTDLMNLVISSSNLFVMQKEIDIYTTLKQWMFLRLNPGWKGTMKQLLVNANNWFSRHKEHDGSISFLETKQGIVFQPVFKNLRFQHIICDLASTKVIEQDALIPSEWLSCVYKRQWYTLLRAQQYREIGPRDITETELEEYSMRCGKRIVRDGTYAWKWSGYNFGVHLYVVFTSHFIIFKRHAFSQPYDGSICLQPQRNIAFRLTLVYFGSSGKLSFRKTTGYKILTFEKDEEQMVMKLDSVALSFPLYIFCNFLFISLENPGN", "length": 498 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1LLV6-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNLFIYVLLLSIWTSSCLDRNESNGSATAVTTHAEFKQTKLQELRRRLLIIIIGTLITGYMVTCTCFLHYSCDSEEAHKATKDKKEDITIKASRSSKISFTDSKSPTAGLGDPERQSVVSRIDKSSGPSSPRKVPSSAEKLVRPSSQKKPSKPSAPKKVLGSPPQEKLHRTRSPKKAHRQAHAHKLVSQVSPSYPEKAIKPTWPPSLQCRVKPTKTPLPYPKNQSFPEHSSADKLTKRQRYLKLKCPASAGRAEILSRPQPVKFCRCYKEKCLVCRAVSEPFITHVSEANKKHVPVPLFSRELKHFYKSYKKKQPKYNTLYGNMSDSDITTYNSDGESDREVIIMCNIKCKEDIYKNSPNN", "length": 361 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1LUU6-1", "protein_name": "Guanylyl cyclase domain containing 1", "gene_name": "GUCD1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTGPRCRRKQRPSGRPGPRGTRAPQHPTPDAGWTARRAAGAAGAEARGRDLPPQRKPAKPTAPGKGRPERGECPRRADRGGGDPEERAGGRPAWGPGAGRGGAWGRSRLPPLLPPGRWCWRPGKPARAGRALSSPVDARAAAGAGPGPWEPRAARVMRTEVDAEAAGPPLEPDEPTQSLSIQDQETAFLLEDSCQLKPGQPLPGRPWPSGDFVQLPVPIIQQLYHWDCGLACSRMVLRYLGQLDDAEFEQALQELRLTRSIWTIDLAYLMRRFGVRHRFCTQTLGVDKGYRSQSFYRKHFDTEETRVNQLFAQAKTCKVLVEKCRVSVQDIQAHLAQGHVAIVLVNSGVLRCDLCSSPPKYCCFTPSGPRCFCRSPDYQGHFIVLRGYSRAAGCVFYNNPAYADRMCSASISNFEEARTSYGTDEDILFVYADS", "length": 434 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1M0W3-1", "protein_name": "IF rod domain-containing protein", "gene_name": "LOC787600", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTCGSACFSSRSGVRSSSSCVTTQRYAPGRTFSCVSACGPRPSRCCITAAPYRGVSCYRGLTGGFSSRSVCGGSRAGSSSRSFGYRSGGPSPPCITSVSVNQSLLKPLNLEIDPNAQRIKHQEKEQIKSLNSKFAAFIDKVCFLEQQNKLLETKWKFYQNQRCCESNLEPLFNGYIETLRREAERVEADTGRLASELNSLQEVLQGYKKKYEEEVALKTTAENEFVKIKQEVNRAYVLKGDLEANAHSLVEEVGFLKTLYEEELRVMQAHISDTSVVVKMDNSRYLNMDSIVAEIKAHYDEIASRSRAEAESWYRSKYEEIKATVIRHGETLRRTKEEINELNRLIQRLTAEIENAKSQNSKLEAAVTQAEQQGEAALNDARGKLAGLEKTLQKAKQDMACLLKEYQEVMSAKLGLDIEIATYRRLLEGEEQRLCEGISAVNVRVSSSRGGVVCGDLSATRTCGIGSYGVGACGSSCKKC", "length": 480 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1MFB0-1", "protein_name": "Uncharacterized protein", "gene_name": "LOC112441459", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNLFIYVLLLSIWTSSCLDRNESNGSATAVTTRAEFKQTKLQELWRRLLIIVIGTLITGYMVTCTCLLHYSCDSEEAHKAAKDKKEDITIKASRSSKISFTDSKSPTAGLGDPERQSVVSRIDKSSGPSSPRKVPSSAEKLVRPSSQKKPSKPSAPKKVLGSPPQEKLHRTRSPKKAHRQAHAHKLVSQVSPSYPEKAIKSTWPPSLQCRVKPTKTPLPYPKNQSFPEQSSVDKLTKRQRYLKLKCPASAGRAEILSRPHPVKFCRCYKEKCLVCRAVSEPFITHVSDANKKHVPVTLFSRELKHFYKSYKKKQPIYNTLYGNMSDSDITTYNSDGESDREVIIMCNIKCKEDMFKNSQNN", "length": 361 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1MI36-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGSSSGSKAEFIVGGKYKLVRKIRSGSFGDMYLAINITNGEEVAVKLESQKARHPQLLYESKLCKILQGEVGIPHIRWYGQQKDYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMMGRIEYVHTKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKNLTGTARYASISAHLGIEQSRRDDMESLGYVLMYFNRTSLPWQGLKAATKKQKYEKISEKKMSTPVEVLCKGFPAEFAMYLNYCRGLRFEEAPDYMYLRHLFHILFRTLNHQYDYTSDWTMLKQKAAQQAASSSGQGQQAQTPTGF", "length": 325 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1MQ28-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "KEQVLQPTTVVSLEGAVAEISCNHSVSDVYDFFWYLHFPGFAPRLLIKGLGPSQQGRYNMTYERFSSSLLILQVQTADAGVYYCALRYTEAGHP", "length": 94 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1MT47-1", "protein_name": "Uncharacterized protein", "gene_name": "LOC112444909", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MLGCEGGKRPLKPPKKQAKETDEEGKAFKHKQKEEQKTLEGLKGQIMGKVPLATGGIKESGKQ", "length": 63 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1MUP8-1", "protein_name": "E3 ubiquitin-protein ligase", "gene_name": "LOC100336539", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSRLTERALPTGTSNGAPSSRRAPVLTGTTVSNNDLASLFECPVCFEYVLPPITQCKSGHLVCGNCRPKLTRCPTCRVPLTSIRNLAMEKVANLVLFPCKYTSSGCGKTMPPTEKADHEEHCEFRPCRCPCPGTSCGWQGSMDAVVPHLMQHYNESIITLRGEVVVFLAVNINLAGTLEWVMLQSCFGFHFLLVLEKLEIYDGHQKFFAVVQLIGTREQAENFTYQLELNGNRRRLSWEATPLSIHEGIATALINSDCLIFDSEVAELFAENGNLSIDVTISMC", "length": 284 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q2TUK0-1", "protein_name": "Uncharacterized protein", "gene_name": "LOC121109925", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEQQGHGERGNWQTKVWKTVALVLVTVAVASFGVYCVGGLVEGIKTTAGVTARLVRRDGEIVSLDEELAKVQRQLHVLQWRARDITERALHEALRRTELPGFTGEAVQKIIHQVLEKLEESPFQMTNYASKTSGAAIVRSKTSPSWIGSGRVFWQSLPLVAYMRPPEVILEPDNHPGNCWPFPGSQGHVFIKLPVAVFPTAVTINHGVPAAAYHADSISSAPKDFAVYGLQEEDDEKGTLLGEFIFMPGQAPGQTFQLKNEHSAFIKYVRLQVLSNWGHPEYTCVYQFRLHGDPAPDGDARGKLSA", "length": 306 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A3Q2UEY0-1", "protein_name": "Mab-21-like HhH/H2TH-like domain-containing protein", "gene_name": "LOC124418381", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MALVLVLALLVRALIVSGSDHAVMLERVQQHEKEQRNGEQSWVDMPALLFTLLHYWKIWLCTGLFVFLFWNMWRSLKRKQHEEGGQQEQQEREEQVEEVEPEEQQEQVEQEEQLERVEELERVDQVEHVEQEEREDQGEQVQQEEQVEEVEREDEEDEYFYHSALTRYIARRAWEKMQGRATKCVLVEELMRDLLQTFTFVCPNSFYPVLQPAIGVGSAFEGWSPCEEDIVYHLLVPIKAPHGHVFHPELGEEGDMLARNSRIRVELVCMCTREQQLGDVLCFLHHSQEELSQNQQPSLLQTLCTGSYLDVQKTAAWFNKQVPRIWRLTHRAHRYGLKVLPSSRSCKLQVTDTSSGEKVHVELLFGVQQGNLDIFLSSQNAEAVFTPSTTWPQSCAVAERKYFEYVARTAGPNSCHLVCLRLFAHILVGMGFSSYTIKTLLLHLLAIIPLEDWRRRHFLSRLENLLQYLQYCLNDKLLNHFLLGNATMPDEVVLPQAFQTASPLNLFQHLEQDPDAHSRALRDFKELKDRLFRLLLFGR", "length": 539 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A494C0N9-1", "protein_name": "Protein FAM246B", "gene_name": "FAM246B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATPGRPWAQARSAYRASEVLRRVTGRRRDPGPQSNGPGREDARAPGRLARLLRQLRAEAASRSEVPRLLKLVERAGAGAAGAGERTGAHSRGSVCSVCGEPRGRATYPAGVLEVSERRLQEGLAAVREELGAEIEALRAELRAELDALRALLPPPPPSPPARREPRAVPRAAPRGPTLLRTLGTVSALVAASRPADDAPDGPAECGAHRAPARKNHKKMPVPPGAPQGGGD", "length": 232 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A494C0Z2-1", "protein_name": "Speedy protein E13", "gene_name": "SPDYE13", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGQILGKIMMSHQPQPQEERSPQRSTSGYPLQEVVDDEVLGPSAPGVDPSPPRRSLGWKRKRECLDESDDEPEKELAPEPEETWVAETLCGLKMKAKRRRVSLVLPEYYEAFNRLLEDPVIKRLLAWDKDLRVSDKYLLAMVIAYFSRAGLPSWQYQRIHFFLALYLANDMEEDDEAPKQNIFYFLYEETRSHIPLLSELWFQLCRYMNPRARKNCSQIALFRKYRFHFFCSMRCRAWVSLEELEEIQAYDPEHWVWARDRAHLS", "length": 265 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A4X1TRA8-1", "protein_name": "Small ribosomal subunit protein eS19", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPGVTVKDVNQQEVVRALAAFLRKSGKLKVPEWVDTVKLVKHKELAPYDENWFYTRAASTPRHLYLWGIAGVGSMTKTYRGHQRDRVMPSHFSRGSKSVAHRLLQAREGLKMVEKDQDGGRKLTPQGQRDLDRIAGQVAAAKKKH", "length": 145 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A4X1TY10-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100627324", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MENYNQTSIYFILLGLFPSSRIGMFLFIIIVLIFLIALFGNFSMILLIFLDNNLHTPMYFLLSQLSLMDLTYISTIVPKMAYNFLFNDKSISFIGCGIQSFFFLTLAGAEGLLLAAMAYDRFVAICFPLHYHIRVSKRICVLMIIGSWIMGSINSFAHTAYALNIPYCQSRAINHFFCDVPAMLTLACIDTWVYESTVFVSTTIFLLVPFTCIAFSYGRILLVVHHMNSTEGKKKAYSTCSTHLTVITLYSAPFAYTYLRPKFLRTPTEDKVLAMLYTIFTPMLNPIIYSLRNKEVMGALRRVIQRICSVKM", "length": 312 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A4X1U699-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100524234", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRRENQSSVSMSKFVLVGLHIWPEQQGMVFALFLGMYLTTVLGNLLIILLIRLDPRLHTPMYFFLSHLAFSDVSFSSVTVPKMLMNMQTQDQSIPYAGCVTQTYFFIFFSCIDNLLLAVMAYDRYVAICHPLRYAIIMKEELCLCLLAGSWLLSCAYALTHTLLLAQLSFCADNIIPHFFCDLASLIKLSCSDTSLNELVIFSLGPAVFIFPLSGILVSYGCIVVSILSVHSPKGIFKALSTCGSHLSVVSLFYGTSMAVYLSSSSGQSHDKDTIASIMYTVVTPLLNPFIYSLRNRDMTLALQILFRNSNLLAK", "length": 315 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A4X1VK25-1", "protein_name": "Elongin-C", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "RSYGGCEGPDASYGKLIASDKFIVKREHVLTSGAIKAMFSSPGQFAEKETDVVNFRETPSGIPSAALWKVCMYLPHKVCYTSNTSEIPEFPINSEFPIAPDIALEPLMAANLLDC", "length": 115 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A571BD55-1", "protein_name": "BTB domain containing 35, family member 26", "gene_name": "Btbd35f26", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSVYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A571BF50-1", "protein_name": "WD repeat domain 88", "gene_name": "Wdr88", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTKDNEEILNSPDQVRKGSPDVKKKKKIKKKRVKPKGDLDSKKLDFVEDSWWKGSLKNKNLDFAEYNWVLVDNRRVSVDSRKSSADSKRGSADSKRGSADSKRGSADSKRGSADSKRGSVDSKRGSVDSKRGSVDSKRGSVDSKRGSVDSKNRFSPKKMDFSEDREISQPTFLRAQQSKVPWALMRALGLFKLSLPDIRRYYNLTSHDPLALDKDRQPREKSHMATVKKFWGNQQPLSKIPYKILIGHDHIVSSCHFCMNDTRFLSSSYDCSVKLWDAEDGTVIWDFEPRPKAPVLECSITADNRRIVASSYDKTVRAWDVETGQLLWKVRHDTFVVCCKFSPNGKFVLSALDVDRGIYLMDPENITTVIHMKDHHQRSITSCCFDPDSQKVASVSMDRCIKIWDITSRTTLFTIPKAHYNAISDCCFTSTGHFLCTSSWDKNIKIWNVHTGEFRNRGACVTLMKGHEGCVSSCCIARDSSFLISGGFDKTVAIWDVGGGYRKLALKGHEDWVTDVAISNNKKWILSASKDSSMRLWNIEEIDKIPLVSENKKAMGLKVRQVGIR", "length": 565 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A571BG45-1", "protein_name": "BTB domain containing 35, family member 25", "gene_name": "Btbd35f25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGLQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A571BG86-1", "protein_name": "BTB domain containing 35, family member 8", "gene_name": "Btbd35f8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLSCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESRHGVINLIIKNEDIDTRSLHFVFGALYRDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A5G2QG78-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100523228", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTRGENTTNITDFVLLGFSDFPQIRAALFVVFLVIYILTLTWNLCLIVLIRMDSHLHTPMYFFLRNLSFIDICYVSSTAPKMLYDFFQAKPTITVVGCAIQYFVCSTMGLSECGLMTVMAYDRYAAICNPLLYSSTMSPSLCGRMVLGSYMAGLSASLSQVCAMLQLHFCGPNVIHHFFCDMPQLLVLSCSDTFFLQLLTLVLTVIFGILNALVIMMSYVYIVISVMKITSTKGWSKAFNTCASHLTAVTLFYTSIIFVYLSSSSGGSSGLDRFAAVFYTVVIPMLNPLIYSLRNKDIKDAWKRLKKRKECC", "length": 312 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A5G2QIN7-1", "protein_name": "ADAM metallopeptidase domain 7", "gene_name": "ADAM7", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSNSHYLSALFSREFLASNYSETYYSTKGEEVTTHPQIMDHCFYQGSIIHEFDSAASISTCSGLRGFFRVNDQRYLIEPVKYSDEGEHLVFRYNPKVQHAANYSCTELNFTRTAVLKDNTKSMEDSKMESIEKEKHIELFIVADNNVYHRNPNSKVRNRVWGMVNFVNMIYKTLDIHVTLVGLETWTNGDKIEIDSNIETTLKRFSAWQEIILKKKKNFDHVVLLSGKWLYTSAQGTSYPGGMCLPYYSSSVVKDLLPDLNTIASRMAHQLGHSLGMKHDDYPCTCTLGKCVMDSGGSIPALKFSKCSRTQYQQYLKDFKPTCMFDIPFSDKLSDYPYCGNKKLDDGEECDCGPVQECTNPCCDARKCMLKPEFTCAEGECCESCQVKKAGSLCRPAKDECDFPETCTGHSPACPKDQFQVNGFPCKDAKGYCFMGNCPTRDDQCSELFDNEAKDSSDICYKMNKNGNKFGYCKNEEQTLIPCEEKDVKCGKIFCTGGKHASILGEEKVYHLKKPLTQNVTECKTFFLYHKSKDFGLVAPGTKCGEGKVCSNSECVTIEKAYNSTDCPSPCNENAVEDGDLGCQCEGVQASVDWEETLNVTNISILVVVLILVIIGVLSAVLLIRYQKCIKLKQVQRPPSEALGVENKGYTGDEQQTRTEPILPDIHPLHRRTAESLARLPTSFSSPHYITLKPASKEPRGTADPNPSAKVSLKLDIQNGCASLS", "length": 725 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A5G2QM02-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100623139", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTGGENTTNITAFVLLGFSDFPHIRAALFVVFLVIYILTLTWNLCLIVLIRMDSHLHIPMYFFLSNLSFIDICYVSSTAPKMLYDFFQAKPTITVVGCAIQYVVFSTMGLSECGLMTVMAYDRYAAICNPLLYSSIMSPSLCGRMVLGSYMAGLSATLSQVCAVLQLHFCGPNVIHHFFCDMPLMLGLSCSDTFFVRVLTAVFTVIFGIINALVIMMSYVYIVISIMKITSAKGWSKAFNTCASHLTAVTLFYTSGIFVNLNSSSGGSSGLDRFAAVFYTLVIPMLNPLIYSLRNKDIKDALKRLKKRKECC", "length": 312 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A5G2QUE5-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100524011", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRRENQSNVSKFLLLGLPIQQEQQGMFFALFLGVYLTTVLGNLLIILLIRLDPRLHTPMYFFLSHLALTDISFASVTVPKMLMNMQAQDHSISYAGCVTQTYFFMFFACIDNLLLTVMAYDRYVAICHPLRYTIIMREELCICLLAGCWLLSCAYALTHTLLLAQLSFCVDNIIPNFFCDLAALLQLSCSDTSLNELVIYTSGAAVFIFPPSGILVSYGRIGISILRVPSTKGICKALSTCGSHLSVVSLFYGTIMALYFSPSFGQSHYKGIIASVMYTVVTPMLNPFIYSLRNRDMTLALEILIRNKNLFTT", "length": 313 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A5G2QWK6-1", "protein_name": "Calmodulin 3", "gene_name": "CALM3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "VSAEREEEGVALKFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEVTASPVLGPAREGPRASAPSWGGKQPLAIACNQPRRSSGFSWDLPSFENLLSSTLWSPASGDGRGVEHSGRPS", "length": 214 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A5G2R7Y6-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100524140", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGQRNQTSSLADFILEGLFDDSPAHAFLFSLTMVVFLVAVSGNTLTILLICADPRLHTPMYVLLSQLSLMDLMHVSTTIPKMAINHLSGTKSISFVGCATQYFLFLSLGGAECLLLTFMSYDRYVAICHPLRYAVLMNRKVGQMMAVMSWLGASVNSLIHTVILMHFPFCGHRNIHHFYCEFPAVVQLVCGDITVYEIAVYIGDIVLLLLPIVLISASYVFILHSVIHMHSAGGKRNAFATCSSHLTVVSLWFGACIFSYMRPRSQRTPLQDKVGSVFYTIITPTLNPLIYTLRNKDIAKALKRVLGREMITQNPKVRLP", "length": 320 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A5G2RGH3-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100524855", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGRRNQTSSLADFILEGLFDDSPAHAFLFSLTMVVFLIAVSGNTLTILLICADPRLHTPMYVLLSQLSLMDLMHVSTTIPKMAINYLSGTKSISFVGCATQYFLFLSLGCAECILLTFMSYDRYVAICHPLRYTVLMNRKVGQMMAVTSWLGASVNSLIHTVILMHFPFCGHRNIHHFYCEFPAVVQLVCGDITVYETAVYISDIVLLLLPIILISASYIFILHSVIRMHSAGSKRNAFATCSSHLTVVSLWFGACIFSYMRPRSQRTPLQDKVGSVFYTIITPTLNPLIYTLRNKDIAKALRRVLGREMITQNPKVRLP", "length": 320 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A668KLA6-1", "protein_name": "Predicted gene, 52955", "gene_name": "Gm52955", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNSSSEHCNVSDWLRLEATVKASVYVVAFSITTSLTIVIIAIVSQSLQLRKEVRLVLLCHHLLCISSYCGLGVVFQGMGALLANSPLLLCWLVFGAQLSVGEGILLTLTLMALNTYLAICYPLNSPSFVDSAKYRILAGTWTTVILKNVGLFLIEGTSPTPASVFQSAPLCPVILNGMPARVIGMFSLAFLLSVILVSYCLIYREGKRAGHFNKSNIKARRTVLVHLLQISLHVIPTLIIIGLGKQCGVFFFALNLALFGIFAFAQCFNPLVYGLHNRDLQSKLYPSLCCQKKLLP", "length": 296 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A668KLA7-1", "protein_name": "Predicted gene 7582", "gene_name": "Gm7582", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNSSSEHCNVSDWLRLEATVKASVYVVAFSITTSLTIVIIAIVSQSLQLRKEVRLVLLCHHLLCISSYCGLGVVFQGMWALLANSPLLLCWLVFGAQLSVGEGILLTLTFMALNTYLAICYPLNSPSFVDSAKYRILAGTWTTVILKNVGLFLIEGTSPTPASVFQSAPLCPVILNGMPARVIGMFSLAFLLSVILVSYCLIYREGKRAGHFNKSNIKARRTVLVHLLQISLHVIPTLIIIGLGKRCGVFFFALNLALFGIFAFAQCFNPLFYGLHNRDVQSKLYPFLCCRKKLLP", "length": 296 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A668KM50-1", "protein_name": "RIKEN cDNA A930007A09 gene", "gene_name": "A930007A09Rik", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSLSELPQKNTDLAEMQSGPLGRCSHFFWLGVAFDAVGVAVLFTGVFANLLFYDMLLYLGSIIIFVSLLWWISWYTGNIEALPEDPLRGTSPRESGVHRSGSRRFSLTLRSVSDTFQRIRRRRRRRLHPRVVQRISSISSTDPGQLERNCDARTSGGRALFRSAKPEAVLNQFSRVQTSKSLPLGIVHTGLSICTSRSQPVFSVTSQTYPLASDSNSQMAMSSDSHVYLDSHSQEHSKISVASQIYPLEREESQSHLLVIPDSLSMVPVTSQSQILPSVSSESCVPLGPHSQGRSKISVATQIYPLEREESQSHFLVIPDSLSMVPVTSQSQILPSVSSESCVPLGPHSQGRSKISVASKIYPLEREESQSHLLVIPDSLSMVPVTSQSQILPSVSSESCVPLGPHSQGRSKISVATQIYPLEREESQSHFLVIPDSLSMVPVTSQSQILPSVSSESCVPLGPHSQGRSKISVASKIYPLEREESQSHLLVIPDSLSMVPVTSQSQILPSVSSESCVPLGPHSQGRSKISVASQIYPLEQEESQSHFLVPMPSDSFPVVPMTSQSQIQGSLAQQSHLQNLPLASQTPETDKASKSHTLAKGVPGVPPGSAQTQHPQASLAQTSQISSPVRKVPKN", "length": 636 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A8C2LDI6-1", "protein_name": "Large ribosomal subunit protein eL33", "gene_name": "LOC100774916", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSGRLWCKAIFAGYKRGLCKQRGHTALLKIEGVYARAETEFYLGKRYAYVYKEKNNTVTLRCKPNKARVIWGKVTKAHGNSGMVHAKFRSNLPAKVIGHRIRVVLYPSRI", "length": 110 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8C2LMV8-1", "protein_name": "Large ribosomal subunit protein eL21", "gene_name": "LOC100755948", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MTNTEGKRRGTRYMFSRPFRKSEVVPLAMYMRIYKKGDIVDIKGMDTVQKGMPHKCYHGKTGRVYNVTKHAVGIIVNKQVKGKILAKRINVQMKHIKHSKSRDSFLKQVKENDQKKKEAKEKGTWVQLKRQPVPPREAHFVRTNGKEPQLLEPISYEFMA", "length": 160 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8C2LSR6-1", "protein_name": "Large ribosomal subunit protein uL5", "gene_name": "LOC100751955", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSQDEGEKENPMWELHICKLCLSICVEESRDRLTRAAKVLEQLKGETPVFSKARYTMRSFGIRSNEKIAVQCTVHGTKTEEILEKGLKVQEYELWRNNFTDTGNFGFEIQEHIDLAIKYDPSIRIHGLDFYVVLGRPGFTIADKHRTGCIGAKHRISKEEAMRWFQHKYDGIILPGK", "length": 177 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8C2LUM6-1", "protein_name": "Tubulin alpha-1C chain-like", "gene_name": "LOC100757824", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MCECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETDTGKHIPRVVFVDLEPTAIDEVRTGTYRQLFHPEQLITGNEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSRFTSLLMEWLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYPTPLPE", "length": 288 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8C2LZU4-1", "protein_name": "Glia maturation factor", "gene_name": "Gmfg", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSDSLAVCEVDPELKEKLRKFRFRKETDNAAIIMKVDKARQMVVLEEEIQNVSPEELRLELPERQPRFVIYSYKYLHDDGRVSYPLCFIFSSPVGCKPEQQMMYAGSKNRLVQTAELTKVFEIRATDDLTEAWLQEKLAFFG", "length": 142 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8C2M625-1", "protein_name": "U3 small nucleolar RNA-associated protein 15 homolog", "gene_name": "LOC100755487", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAGYKPVAIQTYPVLGEKITQDTLYWNNYKTPVQIKEFGAVSKVDFSPQPPYNYAVTASSRIHIYGRYSQEPIKTFSRFKDTAYCATFRQDGQLLVAGSEDGVVQLFDISGRAPLRQFEGHTKAVHTVDFTADKYHVVSGADDYTVKLWDIPNSKEIQTFREHSDYVRCGCASKLNPDLFVTGSYDHTVKMFDARTNKNVLCVEHGQPVESVLLFPSGGLLVSSGGRYVKVWDMLKGGQLLVSLKNHHKTVTCLCLSSSGQRLLSGSLDRKVKVYSTTSYKVVHSFDYAASILSLALSHEDETIVVGMTNGILSVKHRKSEAKKESLSRRRRPAYRTFVKGKIYMKQRDDIMINRPAKKHLEWYDKDLKSFRISKALDRVLEPNCVIKTPEVTVSIIKELNRRGVLANALAGRDEKEITRVLNFLIRNLSQPRFAPVLINAAEIVIDIYLPVIGQSPVVDKKFIVLQGLVEKEIDYQRELLETLGMMDMLFATMSRNDSVSLSENVPAELPEKTESPCQPGDTDKNS", "length": 527 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8C2MXE3-1", "protein_name": "Glycerol-3-phosphate acyltransferase 1, mitochondrial", "gene_name": "Gpam", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDESSVTLGTIDVSYLPNSSEYSLGRCKHATEDWGDCGFKTTFFRSATLKWKESLMSRKRPFVGRCCYSCTPQSWERFFNPSIPSLGLRNVIYINETHTRHRGWLARRLSYILFVQERDVHKGMFATSVTENVLNSSRVQEAIAEVAAEMNPDGSAQQQSKAIQKVKKKARKILQEMVATVSPGMIRLTGWVLLKLFNSFFWNIQIHKGQLEMVKAATETNLPLLFLPVHRSHIDYLLLTFILFCHNIKAPYIASGNNLNIPIFSTLIHKLGGFFIRRRLDETPDGRKDVLYRALLHGHVVELLRQQQFLEIFLEGTRSRSGKTSCARAGLLSVVVDTLSSNTIPDILVIPVGISYDRIIEGHYNGEQLGKPKKNESLWSVARGVIRMLRKNYGYVRVDFAQPFSLKEYLESQSQKPTSAPLSLEQALLPAILPARPNDAAESEDTSSNEPRNTADEAFRRRLIANLGEHILFTASKSCAIMSTHIVACLLLYRHRQGIHLSTLVEDFFVMKEEVLARDFDLGFSGNSEDVVMHAIQLLGNCVTITHTSRKDEFFITPSTTVPSVFELNFYSNGVLHVFIMEAIIACSLYAVLNKRGSGASAGGPGSFISQEQLVRKAASLCYLLSNEGTISLPCQTFHQVCHETVGKFIQYGVLTVAEQDDQEDVSPGLAEQHWDKKLPEPLNWRSDEEDEDSDFGEEQRDCYLKVSQSKEHQQFITFLQRLLGPLLEAYSSAAIFVHNFSGPVPETEYLQKLHRYLITRTERNVAVYAESATYCLVKNAVKMFKDIGVFKETKRKRVSVLELSGTFLPQCNRQKLLEYILSFVVL", "length": 827 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8D1BQI2-1", "protein_name": "Uncharacterized protein", "gene_name": "LCE5A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSCQQNQQQCQPPPKSLPKYSTPKFPGPCPPLVSSCCGSRSGHGRCYSSGGGGCCLSHHRRRRYHPCQPQSSNCCDSGGGQQSGGSGCSHSSGGSGCCSGGCC", "length": 103 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8D1VKI8-1", "protein_name": "Uncharacterized protein", "gene_name": "NCR3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MARMLLLILIRVHSGSCALWVSQPPEICTQEGTPAFLPVPSTPARGDWPLALSHGTGTNWPQGRRVVVLGQGVRTGNGTPLVVERGPAQLATPTIFLLRAGFYAFGFLSVAIGSTIYYQGKCHRHMGTHCRSADGL", "length": 136 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8I5XVN6-1", "protein_name": "SPATA31 domain-containing protein", "gene_name": "LOC689526", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MESFLLLMNSAIESWMNTSTMDIATDLSIAILCGVGLFFLLIPFLKDCPLSPASGNKTDIPKDVKRGRSNTRRKTDVEKGCRDGGKTVEETKTPSQPMKILTRQLLQDSTPQIFWNSSQKLDHLLLSQLFSSLTSLEDLILQKFNRRFWGTSSIFSESVVAMAHVLRNPSFPQQKSVRFSDPCVTDQAPSQAQGLRQQHRYHPRLHRQRKTSLVGMTWVPEKKILPISTPKQIHPCLKRRAYGVSCPTTEKGIQTSLPPECLSHKHGLYSKAVKGYVKRNHQKAIGKPPGNWLRDTLKTKAIRPASILSEHLRMFLHHKEPQTKDKATNVEKQQGTCIRSPPSKKLKQFQGRFPPNTDHYCKRRPQLSQPGQPSILNSKSYKLRKIIQSVLAGMTLMKDRADFSMQSQFSQAPQSSVCNAKRYKYSKRMGSVPRRVPLKKDTARYDMGKPIKKCLGAGTKNVPHSACSILGKRLRARNLALKKGQASVMNPTGNYCLHDSKAEMKLASNNTALPVQCRRTPYLQILEALNPIPPGVLASKLPRIVFPSSPICDFKEEYYSKAATVLKNLHHQDPGGTRVKSTSAASLESALSMCSAAKIQKTQRAPPPAASRGLSKAHTDLLKRHLSIQHSALYFEQGRIIQGTGKGSLQQNTNPQKAKHAPLKSFHEGDSRHHSWNGTMVGPGKRVPPAAAKQTKAVEVKKETPYAWSLGSNESHTGKDINISPRVFGSLGAKRSPGHLQTCTPQHSQDSTLRTQGHRNIILCSNKQPQPRPGRHDPECPSTVHPAKVNLSSEHSMSSFQNTCQKPKTAQGSCERADTKENRVLKDKIRINHLKDLCPHKERQGSIRPTAISQGGRLGRSRPCSLSSTQLKDTAKTRTSDKRQATSKSSWKSDIREVLKYGYVGSKDIIGQEDTSKKDQPPAVTERTEEDWTGEKAMCNMIAHLQYLTNFLFEIMEDTEWDPSKLQGCEVESLTFQLGSSSDSSEGDDDINQGTSTSTMSFGQTSPEMHNCSFTKTGIGDKTQSEIKAKTACDQHLNQVNRGMFSDQLPMPKEYDLSCRYRGIQHQQELGLPDQTFYQYKLRMTHCPHGGTKGHNYSFGYRKLGDQQQPDFTHKALDPHQSAKEDMGCVSCLSPKGSRPVKHRRTDCFSP", "length": 1151 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5XWP3-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "ENSRNOG00000063695", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQRDMCHMTPYRLLCVLVALALSGCNVAQEVTQVQSTASRQEGEEVTLDCSYETSYVAYYLSWYKQHLSGDIIFLIHQISSSTAEERSGRYSLVFQKSLKSISLVISASQPEDSGKYFCALSDLTQC", "length": 127 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5Y4M0-1", "protein_name": "Large ribosomal subunit protein uL14", "gene_name": "LOC108350588", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSEQRRGGSSGAKFRISLGLQVGAVINRADSTGTKNVYIISVKEIKGRLDRLPAAGVGHMVMATVQKSRPQLRKKVHPAMVIRQQKSCGRKDGVSLYFEEDAEVIVNNKGKMKGSAITGPIAKEHADSWPRIASNAGSTA", "length": 140 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5Y5C9-1", "protein_name": "Ribosomal protein L32 like 2", "gene_name": "Rpl32l2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAALRPLMKPKIIQKRTKKFIRHQSDRYVKIKRNWRKPRGINNRVRRRFKGQILVPNIGYGNNKKTKHMLPSCFRKFLVHNVKELEVLLMCSKSYCAEIAHNVSSKNRKAILERAAQLAIRVTNPNDRLCSKENE", "length": 135 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5Y6V7-1", "protein_name": "UPAR/Ly6 domain-containing protein", "gene_name": "Pate4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRNTEPLFDIVINCPIAPQFILKILLFPYPANTNLICNTCNRSENSECKNGTGQCTAPEGGSCSTISIYHGQRHVLSKQMCLGHCEEKPHYNGDFMIYVMCCSKNLCNSF", "length": 110 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5Y7P1-1", "protein_name": "Heterogeneous nuclear ribonucleoproteins A2/B1", "gene_name": "ENSRNOG00000069815", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEREKEQFCKLFLGGLSFETTGESLRNYYERWGKLTDCVVMRDPASKRSRGFGFVTFSSMARPHSIDGRVVEPKRAVAREESGDPGAHVTVKKLFVVGIKEDTEVHHFRDYFEEYGKIDTTEIITDRQSGKKRGFGFVTFDDHDPVDKIVLQKYHTINGHNAEVRKALSGQEMQKAQSSRSGRGGNFGFGNSRDGGGNFGPGQGSNFRRGSGGWESSDGYGSGRGFGDGYNGYGGGTGGGNFGGSPGYGEGRGGYGGGGPGYGNQDGSYRGGYDNYGGGNYGKGNYNDFGNHNQQPSNCGPMKSGNFGGSRNMGGPRDEHRSFPSWKGYNGVFGKQSPLTWIKTHSL", "length": 347 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZKP8-1", "protein_name": "Glycerol-3-phosphate dehydrogenase [NAD(+)]", "gene_name": "Gpd1l2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGATTLRVCIVGFWSWGSAIAKIIGTNVKNQQKFASTVKMWVSEEAVNGRKLTDIINHYHENVKYLPGHKLPENVVAVANLSEAVQDADLLVFTTPHQFIHKICNEITGRVPKKALGIIHMESIDEGPRGLMLISDIIREKIGMDVSVLMGANTAREVAAGEFCETTIGSKVIQNGILFKELLQTSNFCITVVDDADAVELCGALKHIVAMGTNFCNGLHCGNNSKAAVLRLGLVEMITFTRIFCKSQVSTTTFLESCGFANPITICYRGSDCKEAKTFPRIGKTMGNLQKEVLNGQTLQGLKTSALVYQFLKQKGLLAKFPLFVTVYRICYEGRPSTEILTCLQNHPAHM", "length": 351 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZL63-1", "protein_name": "Ankyrin repeat domain 13a", "gene_name": "Ankrd13a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVSDQSRKAAAEGGSSPMVWSRPARAPPGGRADGRGPIVERTTGEGRAGDESRRARTVGFVRGDLGLPKGPAVPQNGGGRVSRRGGLVGRHGAGLGPFRKSGPPPRSVMERLAYFPVRGGSAGSSRFASCQRGRERAGRGVGAAERVPEPVPSPARDPGPPAPPAPDSEALVVRCARHLAARRSPPLALRPVGRAPETPSGGSRLVAGGRSGLGGDLLAMSSARDTSSRFPLHLLVWNNDYRQLEKELRDQNAEALDPRGRTLLHLAVSLGHLESARVLLRHKADVTKENGQGWTVLHEAVSTGDPEMVYTVLQHRDYHNTSMALEGVPELLHKILEAPDFYVQMKWEFTSWVPLVSRICPNDVCRIWKSGAKLRVDITLLGFENMSWIRGRRSLIFKGGDNWAELMEVNHDDRVVTTEHFDLSQEMERLTLDLMKPKSREVERRLTSPVINTSLDTKNVAFERTKSGFWGWRTDKAEVVNGYEAKVYSVNNVSVITKIRTEHLTEEEKKRYKEDRNPLESLLGTVEHQFGAQGQDLTTECATVNNPTAITPDEYFDEDFDLKDRDIGRPKELTIRTQKFKATLWMCEEFPLSLVEQVIPIIDLMARTSAHFARLRDFIKLDFPPGFPVKIEIPLFHVLNARITFGNVNGCSTAEERQSVEGTQAECAASDATNFEVDQSVFEIPESYHVQDNGRNVHLQDEDYEIMQFAIQQSLLESSRSQDLSGPASNGGVSHAHSYEAQYERAIQESLLTNMEGRCPGGLSDSSRFDSDLRLAMELSAKELAEQELRLQEEEAELQQVLQLSLTEK", "length": 809 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZP24-1", "protein_name": "Large ribosomal subunit protein uL30", "gene_name": "ENSRNOG00000064315", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEAVPEKEKKVAAVPGTLKKKKVPAVPETLKKKRRNFSELKVRRLRKKFALKTLRKARRKLICEKAKHYHKECRQMYLTEIRMARMARKAGNVYVSAEPTLAFVIRIRGISGVSPKVREVLQLLRLRQILNGTFVKLSKASVKMLRIVEPYIAWGYPNLKSVNELIYKRGYGKIRKKRIALTDNSLMARSLGKFGIICMEDLIHEIYTVGKHFKEANNFLWPLKLSSPRGGMKKKTTHFVEGGDAGNRETR", "length": 251 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZPV0-1", "protein_name": "ATP synthase peripheral stalk subunit F6, mitochondrial", "gene_name": "ENSRNOG00000066253", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MIVQRIFRLSSVLPSAVSVHLRSNPGVTAVAFNKEPDPVQKLFVDKIREYKTKRQVSGGPVDTGPEYHQDLDREPFKLKQLYGKGEMDKFPTFKFEDPKFVVIDKPQS", "length": 108 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZRI3-1", "protein_name": "Natural killer cell cytotoxicity receptor 3 ligand 1", "gene_name": "Ncr3lg1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASQSCQRGPENAHMHPKGPCCSALCFLCSLGSSPHGSSLGPLRKCGRRSKPVQSSPEGSRVAEWPDGLLSLLLLLWSLLPSAGGLELEMAGTTQIVFLHEDVTIPCKILGSLHLDLSIVGVIWSLKKDGDESEVFKFYGDQLEAVRPGANVSLLGLEHGDASLYLPRFELWEAGEYQCKVVVTPEKKEGTTRLEVVAHPNMSLSEKPATARGGKEKLIICQLDGFYPEALDIKWMGSALKDSHFQEITEGVVTGPTVKNDDGTFSVTSSLALKPALEDHMYQCVVWHRSWLMPQSLNVTVFENTRDSTHGTVPPTAEVGPPVSEPRSVMIYVTIIGLCILLFSVIVCGLWKWKRLTTSNTGLCLRLDVRC", "length": 371 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZS91-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "LOC134482834", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPTETEEELPTPTPKPSISEEGNFHSQYQVLGTSGQGGNGKVLLAHNRLTGTPVAVKVLRKDKQWFQPAMMEANIMRKINHPNIVSLIQVIEKETRIYLIMELVEGQELYQYIRESGHIEEDEARQIFEQILSAVSYCHGKGIVHRDLKLDNIMIDKNKKVKVIDFGLSTQFPPGKMLNHHCGTHSFGSSELLLGHRYDRPKNDMWIIGVVLYCMVVGKLTFDSVIIQDLQRQVVAGVYPAPCGVSKELEDLLSKLLRVNPNFRPTARKAMKHPWFKEHWNGLIVPYEELLPLTPDPAILDAMKSIGLQASVVKHTLKQRKYNEEMATYFFLQKQALQGDGCTAQAQQVSPVAAPFPSLDPAAAFRLEPKRSGSLPVLGTLRVSSSHGHVSHYGQNAHPKGGKRYTVAGRLRPLPMTPTQDHYHKCAVSVPCIQTTSIFSEKSSNKKIKEDNPLSHRAPLEDKPIPSRVRHRGFKGWTRNIANALIKLCCCMPRRKKPRLGQNRISPQK", "length": 509 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZT61-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "LOC134479845", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDITSIKKTLGSQYRVAFFLGQGSYGSVKLAWHRRTQALVAIKTVEISKNTIRAILSEMTTLELLHHPNIISLFQILVTANQIHFILQYAPGGNLVQLISEEGPLPEEKAKKMFGQIVSAIRHCHSLDIVHRDIKPQNILIDGEGNVKLIDFGLAVKCRPGTLLSRHCGTRGFNAPELVLRQPYDGKSSDVWSLGVLLYFITTGYFPFRGNTIDEIEQKITTGTYTVPHHLSGQLENLIHQIFTVSPEMRPSIEEIENHPWIKKCELKIPPMSDPDYKIIEMLCGMGYNAKDILESLQKKRYDEPMGAYLSLKNHVSEGYDLASITPTKPGDPCPPPPPSPAHPSVFGLPLRRRASEPNFGLLHRQPSREQNPLDLILSGLNMGRCVSMPPIAVYYPKKQRSTSTRALHSRPVASPCVYNNMLGVEIILPHKQDIEMNTSSPPQTMGWFKRLRKGIGDCFSRLCCFPRAPKKKTQHRSSKRVAPLKKAASSTI", "length": 493 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZXB5-1", "protein_name": "Uncharacterized protein", "gene_name": "Pilrb2l2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "TALLSSLPGRNLAMARLLLLLLSAACLHTGNSAGYQEKNDFGVDQPDVLSGVQGGSIEIPFSFYFPWKLAKDPQMSIAWRWKHYHGEFIYTSTRPFIHEHFKGRLIMNWTPGQTSGVLRILNLKENDQATYFSSVFLQTPEGMKLWQSIPGTKLIIHALDTTMRSPSIIPSVVPTDDLEYTQGQRNPSLLNLGAMVGMVMAKVVVIIPLYGWMIFLWWKQR", "length": 221 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZY57-1", "protein_name": "40S ribosomal protein S26", "gene_name": "LOC134478821", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSPGPRRPRQEAGSKPRELQQRVLASVKRRCLFSSLGSNTTKKKRNNGRAKKGHGHVQPIRCTNCARCVPKDKAIKMFVIRNILEAAAVRGISEANVFDAYVPPKLYLKLHYCVSCAIHSKVVGNRSCEARKDQTPPPRFRPSGAAPQPPPKPM", "length": 154 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZYE5-1", "protein_name": "Oligosaccharyltransferase complex subunit", "gene_name": "Ostcl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "METKHSALLRTFPFLVLECPNLKLKKPPWVHMLLAMTMYALVVVSYFFITGGIIYDVSIEPPSVDSMTDEHGHQRPVAFLARRVNGQYIMEGLASSFLFTMGGLGFIILDRSNTPNIPKLSGFLLLFDFVCVLLSFFIARVFMRMKLPDCLMG", "length": 153 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZYN2-1", "protein_name": "Non-selective voltage-gated ion channel VDAC2", "gene_name": "AABR07051831.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAECCVLVCPRPMCIPPPYADLGKAARDIFNKGFGLGLVKLDVKTMSCSGGEFSISGSSNTDTGKVSGTLETKYKWCGYALTFTEKWNTNNTLGTEIAIENQICQGLKLTFDTMFSPNTGKKSGKIKSAYKRECINLGYDVDFDFDFGWLAGYQMTFDSAKSKLTRNNFAVCYRTGDFQLHTNVNNGTEFGGSIYQKVLCEDFDTSVNLAWTSGTNCTRFDIIAKYQLDPTASISAKVNNSSLIGVGYAQTLRPGVKLTPSALVYGKSFNAGGHKLGLDLELEV", "length": 284 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZYX3-1", "protein_name": "Methyl-CpG binding domain protein 3 like 3", "gene_name": "Mbd3l3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "LGELGNAGRLTGSMIPSRLQKRRKIQVAKSKRKAKHKSGTTLRNPLRLTSCIFPQPVTVITSYPENKTRYRRDEAKLKKPQQLCALERLKNFQFGGDSKENLSCPLELANAVERIARGMQDEASNQSGDKDQLTSGQVTSDQPPYLETNEHVALQLSPSFSSQGVTLPVPLHLSPSYFLRKVTTGDIQRQAWKVKKARKRLAEALEADRLARQTENMRE", "length": 219 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZZU9-1", "protein_name": "Keratin-associated protein", "gene_name": "ENSRNOG00000070302", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "SPSTCELSSSLHSDCQETCIEPSICQRSCVASSPCQMPCYYPRSSTACSPCQGTYDGSMGVGSNSLKSFGGFTGSLGYGNSGFGSFGFGSCGIRSQGFGCNFHRPGYFSSKSVQSSYYQPGYTSGFC", "length": 127 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZZY5-1", "protein_name": "Ribosomal protein eL8/eL30/eS12/Gadd45 domain-containing protein", "gene_name": "ENSRNOG00000064452", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTKIKAVTEESEAQGEGCSQQHRYQELLVYLNPIAQHPGFPPPDLRKIEKGKKKKKRRPTKQKQIRHGVKEVQKFVNKGKKGIMVLTGDTLRGTAIFQLCARTRICPTSIFPLTDLGAAMGSKHPTCVIMVKLHEEYHEAYDKCLEEVQTLATPL", "length": 155 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A2Z7-1", "protein_name": "Developmental pluripotency associated 1, pseudogene 1", "gene_name": "Dppa1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MMPPQVLISGLLLLLPAAWTTTVTSSDQLWNNHTEVVPTQSPLKISTKDLYIGTSVSAALLILLAGVLAVLKYRHRRKKILESAVVFHGFQNGVFQSTEQSQAVDVYVIEDSKVPVAH", "length": 118 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A3D9-1", "protein_name": "Small nuclear ribonucleoprotein Sm D3", "gene_name": "Snrpd3l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSIGRPIEVLQEAQGYMVTRETITGEVYPGKLIEAEDNMNCQMSNITVTYRDGPVAQPEQVYICDTKIRFPILPNMLKNAPVLENLKNKNQGSRAGQGKAAILKAQVAARGRGHEMGPWKLPEAKTVFSIKENFPSCLLLGF", "length": 142 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A3N0-1", "protein_name": "Uncharacterized protein", "gene_name": "Pramef20-ps2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTVQTPPTLEKLAIQSLIRNEDVAMSSLGELPAVLFPALFKEAFTGKHINLVKEVVAAWPFPCLLVGALMKTPNLETLQAVLDGVDMQLTRKFHTRRTKLQVLDLRNMHHYFWNIQAGEEDSSCSAENSKEKKVVKVFHRYALRKRVKVIVELYIHSCLKEEQTCLLKWAQQRKGSLHFCCTKMKVWNLSLCGIGEILKVFDPQHITELELHTEWTLLELAHFAPYFGQMRNLQKAFLAPLHRIMFSNSNGKRDREAKCIKKFISQFSKFNCLQHLHMFCVHFLRDHMNQVLGCLMTPLTLSITYYLISQKDLDSLSRSQSLFQLKHLDLRGVVLCDLDIMPLRGLLEKVADTLETLDLQWCKMTDSQLYALLPALRHCCQLTMVNFYSNNFSVPILKDLMQHIANWSRIRVQQYPAPLECYDDLAQVSVKRFAKLSSELMYTLGVIRQTKNISFATDICHTCGQRCVYHNGSRLCCCWH", "length": 480 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A3R7-1", "protein_name": "Ubiquinol-cytochrome-c reductase complex assembly factor 3", "gene_name": "LOC120093241", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEAARKALTVVAVLGSGAGVGSILFALVTPGELQKQLMLQEMPERDSRRRDAAVRTKELVMATLKDAAATKENVAWRRNWTVRGDGRSA", "length": 89 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A3T5-1", "protein_name": "Large ribosomal subunit protein mL62", "gene_name": "Mrpl58", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "EHGGRLGPTLEPEPSWNLVAPAARALCSPDSAQTGERHRVQEHLQPGQAVPRIQGRGYRLEGPGEPRKAGRKGRFLLLLDRLSISYCRSSGPGGQNVNKVNSKAEVRFHLASADWIAEPVRQKIALTHKNKINKAGELVLTSESSRYQFRNLAECLQKIRDMIAKASQVPKEPSKEDAQLQRLRIEKMNRERLRQKRINSTIKTSRRMTMD", "length": 211 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A478-1", "protein_name": "T-cell activation Rho GTPase-activating protein", "gene_name": "LOC134485907", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGEIHRTLLCQGPVELTSGRKRNKRYLSLFDDVLVVSTNLTKKKFKIKCIIPLNYLWVVDDVELVRANQTCTCKTIFFYWATGNALATFRSKEQKVQWYTFLTRSINEAKKGIKKTFPLHIFPEDIQTCDSSLCVTATNMDTVNDIMEKLLPMIRVHNIEDYQLWFSPGHKETPRALQGHEYPYDIIMNNVQNNLSKSNSKIFTAFPPLPGLFMENQSWDTGGQFILKPRDSAGSQQQDAKERPRKSCMTSCFHGGSVPHHDQECSDPRDDKRGKLFGQDLSSICQDGKLPTIILDMLSRIKDKGPTTDDIFLITPNGSLCKTIKEKLDNGENVDIYQQPVHVVAWILKEFLQSIKGSLLTSKLYDQWLIVPEKVNDKEKLAAVKSLLEKLPKPNADLLRQLFRILHQIKTNSSVNNMSSFRLSLETAPCILWLPSYRNNILTNDIAKKISLVTFMIDNSPELFGEDIVAVWYETSLYHPPGLKYPCSQNTPSSNGIMEETEHGLSSCPGERTCTPDFDELPRSGAAASIPYEGILASEKGEGNESTTQPEPVQNSPTPQTKKELGNCSPNILKDVNVPAVILDMLSVIAEKGQCSDDIFRMQSEKSHWSLKEKVNTGKHVNLKEESVLTVASVVKDFIKNIEGSLLSCDLYENWLSIPDEGPLLGKIASIQNILLKMPKPNYVLLKQLICVLQKIKAASTNQLDTFDLSVRIAPHVLWNPTCKTLFGRDLSKKLSIIKFMIDNCQELFGENDNIFCEDNQKSYDINLSSDTLNTSGKATLMIETIDDHDVKTSKSNTKKLEMSSAVPHEGGPTAGHNGTTSKYNVPQEKILHD", "length": 834 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A4C1-1", "protein_name": "RRM domain-containing protein", "gene_name": "ENSRNOG00000063783", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "LTCCAINSDPHPDSGLKMEGHDPKEPEQLRKLFIGGLSFEATDDSLREHFEKWGTLTDCVVMRDPQTKRSRSFSFVTYSCVKEVDAAMCAQPHNVDGRVVEPKRAVSREDSVKPGAHLTVKKIFVGGIKEDTEEYNLRDYFEKYGKIKTMEVMEDRLIDKIVVQKYHTINGHNCEVKKALSKQEMQSAGSQRGRGGGSGNFMGRGGNFGRGGNFDGRGGYGGGGGGSRGSYVGGDGGYNGFGGDSGNYGGGPGYSSRGGYGGGGPGYGNQGGGYGGGGGGYDSYNEGGNFGGGNYGGGGNYNDFGNYSGQQQSNYGRMKRGRFGGRSSGSPYGGGYGSGGGSGGYGSRKF", "length": 350 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A5E5-1", "protein_name": "Paired immunoglobulin-like type 2 receptor alpha", "gene_name": "Pilrb1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAQILLLLLSATCLHTGNSGGYTRKNYFGVNQPAVLSGVQGGSIEIPFSFYFPWKLAKDPQMSIAWRWKEVHGEFIYQSTLSFIHEHFKDRLILNWTQGQTFGVLRILNLKENDQATYFSQVCLQTTEGMKCWQSIPGTKLIVTHGVICSLLISPQLSYDHEDPLHHHLCRPHSWPGEHKGPKESFTAEPGGHHWDGRGQSCSHHPPLRMDDLSVVEAKASRVTPKPQPE", "length": 230 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A5T5-1", "protein_name": "Large ribosomal subunit protein eL21", "gene_name": "Rpl21l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTNTKGKRRGTRYMFSRPFRNHGVIPLATYIRIYKKGDIVDIKGMGTAQKGMPHKCYHGKTGRAYNVTQHAVGIIVNKQVKGKIPAKRINVRIEHTKHSKSRDGFLKRVKENDQKKKEAKEKGTWVQLKRQPVPPREAHFVRTNGKEPELLERSPYEFMA", "length": 160 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A8T3-1", "protein_name": "Olfactory receptor", "gene_name": "Or1o11b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "RMNCSQAPGFILLGLSRDPEKWQLFFSVFLVLYLLGLSGNLLLLLAIGADVHLHTPMYFFLSQLSLVDLCFITTTAPKILQTLWTGDGSISFSGCLTQLYFFAVFADMDNLLLAVMAIDRYAAICHPLLYPLLMTPCRCGVLVSGSWGVAHCVSLTHTLLLSQLYFHTNQMIPHFFCDFGPLLLLSCSDAHLNEGLMMALAGVFGISALLCIVSSYSCIFYAVARVPSAQGKRKALATCSSHLSVVLLFYSTVFTTYLKPPSSSYSSGEVVAAVMYTLVTPTLNPFIYSLRNKDVKSSLRRILNMVKSPD", "length": 310 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A969-1", "protein_name": "Uncharacterized protein", "gene_name": "ENSRNOG00000067430", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFFLFWTFPGLELDKLALLSFESSSSIHPRACASTPAFQRSHNPGDAAQQEAKQREAEMRNSILTRVLDQSAWVRLSDLALVKPDKTKAVEHRVQMARYGQLSGTVSEQGFIETPEKVSQQTEEKATVKFNRREVTDSDEDDDY", "length": 144 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A9H4-1", "protein_name": "NAD(P)(+)--arginine ADP-ribosyltransferase", "gene_name": "Art3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGQATARGVIKRKAFPGRQLSLSTTSCPGGKITPAESGNRFESGHHLNVLQRHKRQKRKMKMGHFELVTTLLAAMVLMDVFQVQAEVLDMAENVFDDEYLKCNSRMEMKYIPRMHGEELANDELLQSVWDKAGIQWEAQKAQLSLPKNFKDAYGIALTAYVTEAQDQSPFYHTFNRAVKIAGLSRRRYIYNFPFKAFHFYLVRALQLLRRPCEESYKNVVYSTSPNISFAFGEQNQARLGNFTLAYSAKPQTANEQRLLTIQTCFGVAVGKLLNKESEGIVLIPLSEVFQVSRKGTDDDLILHSINSTCSYYECSFLGGLKAGSCTTNPENPDPGYLNNPDLDSQKLEDSGRKSLDSVKMPEIKVLQGEENPLLPDEKPEDRNRGKANVPTPGLVPVPGPKSHPSSSSGHRLLPSDTASTILLIAAAVDFIAL", "length": 433 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AA84-1", "protein_name": "Ankyrin repeat domain 10", "gene_name": "Ankrd10", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSAGAGAGVEAGFSSEELLSLRFPLHRACRDGDLVALCSLLPHTPRAHLAAEDSFYGWTPVHWAAHFGKVGAGTLRRHFPRGVLLGSERTPPCLESAATARSAPPAPPEGSRAHVQQSGLGVKGWGRGGAEAALAPPGVQGACAAARSPGPRGARGVMGGGAEMGSVWPAPRRTQGACAHLWLFRAGRADRMQLRRFARRPSGFGEWCGRLLLEARREPGASRSCLMETGRRAPLRHKGMDAALAAGGVRSAPAVVDGGLAARPTGPLSQLGPPCLECLIQLVRAGASLNVSTTRYAQTPAHIAAFGGHPQCLVWLIQAGANINKPDCEGETPIHKAARSGSLECISALVGNGAQTDLRNASGLTAADIAQTQGFQECTQFLLSLQNHQMSRFCPNGTLSGGHENILPNHINLGTNRKRCLEDSESLGVKKARTRVPSLDHTMPLANGDAEDDADRMHVDREFAAVSDMKNSSSVLNTLTNGSVINGHLDFPCVAQLNGMESRSDPCLTGSNGISNGQPFPSGQGPVCANGTEEPEKTMGVNPEMCGSLHLNGSPSSCVASRPSWVGDIGESLHYGHYHGFGDTAESIPELSSVLEHSSCVRVEQRYDSAVLGAMQLHHGS", "length": 621 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6ABF4-1", "protein_name": "Nuclear transport factor 2", "gene_name": "AABR07018058.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGDKPIWEQIGSSFIQNYYPLFDNDRTQLGAIYIGASCLTWEGQQFQGKAAIVEKLSSLPFQKIQHSIMAQQYQPTPDSCIISMVVGQLKADEDPIMGFHQMFLLKNINDAWVCTNDMFRLALHNSS", "length": 127 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AC04-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vom1r38", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSMLSQNKTLKSIEEVALHVILLCQVGVGTVANFLLFIHNFSVILTNCQLTPIQVIVTNLAVASAFNLLLLAFPNNVTLFVPRKAPSDLSCKLWYFICLVARSTNLSSTCVLSTYQFVMLLPGNWSRVILKGRAPKIVNYSCYGCWIFSVLNNAYIPVKVSGPQKTQNDTDFKDKWVCSTSGFSVGMSFLRFAHDALFISIMIWTNVSMVILLNRHHHRLQHIHSSNQDHRAYADTRAAHTILMLVVTFLSFYLLDCICTFFHISFVDSRLLLRRIKEVLTASFPTISPFLLIFRGPKNPCSLLSRS", "length": 307 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AC51-1", "protein_name": "Non-histone chromosomal protein HMG-17", "gene_name": "Hmgn2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPKRKAEGDAKGDKAKVKDEPQRRSARLSAKPAPPKPEPKPKKAPAKKGEKVPKGKKGKADAGKDANNPAENGDAKTDQAQKADGAGDAK", "length": 90 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AC66-1", "protein_name": "Eukaryotic translation initiation factor 6", "gene_name": "Eif6-ps1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVVRASFENNCEVSCFARLTNTYSLVAIGGSENFYSVFEGELSDTIPVVHASIASCRIIGRGTSVWGTGMGYWYPTTTTDQELQHIHDSLLDSVQIRRVEEGLSALDNVTTCNDYVALVHPDLDRETEEILAGVLKVEVLTVADQVLVGSYCVFSNQGGLVYPKTSIEDQDELSSPLQVPLVAGTVNRGSEVIAAGMVVNDWCAFCGLDTTSTELSVVESVFKLNEAKPSTIATSMRDSLIDRLT", "length": 245 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6ACC5-1", "protein_name": "Uncharacterized protein", "gene_name": "ENSRNOG00000069094", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "LPLLAFEKYVVCDGELQRLQVSCEVLGDVDPPQRLSASVVQMKQSVVEFLGTLVEQDAQGAAEDMDNALVGDNEEAEGENNSTRTNSDGPFTERPNQRLNNR", "length": 102 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AEL7-1", "protein_name": "Protein phosphatase 4 regulatory subunit 3C like 1", "gene_name": "Ppp4r3cl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEDKLYRVKVYVMMEDKQWKDIGAGQISSKYIDRLQGVCLLVHSESDGSPILECKIQPNVPYQKHQGKVIIWSEAKNHGTAIHFQEPNDCQETWEVICQVQGKDPNVEITQLLTDDLESFKDMLLSWNKVEMSSCELHTLENIADLLSFVNEAPSHKKILTLVLEKEGYIKKLLQLFKTCEKHQNIDGLHYLNNIIRGILFLDNIHLFNIMFSDEFIMDVVGCLEYGPGLDEPKQHRQFLTQNVKFKNVMQITHSQLRKKIQQTYRMQYIYDIVLPTPSIFEVNLLHDLSTMIFFNKIEIITMLQEDEHFLLEVLAQLKDNTVSNERRHELLLFFKEFCAFAKTLHFQKKNTLLKTLIKLGIISALKVVVHMHDYQIQVAALELFAHLVEYSPRLIRAYAMKEAQYSEDNDGLLINIMIKQMTCDSDPEFSRSIILTTVLHAILDPENMRVTTKGHERRKFLNYFYRHCMNKLIEPILSITVENNSDDNRVNICPDNYQNAQLLGAILEILTFCVQYHSKYVKNYIISKNLLSRILILMSSKHTFLILCAVRFMRKMIGLKDKMYNLYIVEKNLFEPVVNAFMHNGHRYNMLNSAIIELFEFIRQENIKSLIANIVEKFFMFFESIQYVQTFKGLKTKYEEEKKKKRERQLRKSLHNIIYQRIYCRHIKAMEVKVKADIFCRQITDKEEEREKGGGGGEGGGGRGGEGEGGREGGGREGEGGGGGKGGRGEGGAVLSMGSDIPSHYDMFVKINEMNERENVIECRKRKSSATSEYSTSCGDTSDNGISTVYCSSLVPLVDYAYDTDGEDDDGSYGNNENEEEEEEEEEEEPPKKKPYFHP", "length": 840 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AFG0-1", "protein_name": "Cytochrome b5", "gene_name": "ENSRNOG00000064959", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFAKEKGKFEDMAKDVKCYTLGEIQKHQDIKNSWAMLHHRVYDLTKFLEEHLGEEEVLRERAGGHASENFEDVGCSTNVQGLSKVHIIGLFHPALITTIKLNSNWWDQLCSPTSQVVVAHTFNPSTREVGAVGFP", "length": 135 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AGM4-1", "protein_name": "Proline rich 18", "gene_name": "Prr18", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLRLLGRVMSFSPMPPPPPPPPPPARTQGGPAARQLSRRPCGPPAASPPAPAAAAAGEKKRRPPEMLLSSSWPSATLKRPPARRGPGLGPGTPQPPTSARVPPQPSPGRGGTSATCSAPRRIACSHIPAGSTASGTSAGAGAGPEDATRFSLSLTPEAILVIQRRHLEKQLLARPRRPFPAPSADPRRPLVPCPRTRSSTLRRGGPTSVPDAPLAVAVSSRPPRASLLPGGLQATMPSPRPSSLRPVLKVSLLNEKHKYDDEEYEEEVEVVDEGLVRKCTEWLRGVESAAAARGRTGHLDSLPHLSTL", "length": 308 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AGS9-1", "protein_name": "Olfactory receptor", "gene_name": "Or5aq7b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEVWNSTGVKEFILIGLTENPNWQVPLFLLFCIIYFIILVGNCGMIFLIWLNVQLHTPMYFFLSNLSFCDICYSTIIAPKMIINFLSEHKSTRLFACILQSFFFAVYATTEVVLLSMMAYDRYVAIANPLMYTVIMTQSICTQMILASYLTGLINSLIHTIGLLKLNFCGPNIVNHFFCDVPPLLKLACSDSHINEILLLVFSGIIAISTLIIVIVSYIHIIIAILRIRSAMGRGKAFSTCASHLTAVALFYGSLTFSYIQPSSQYSMEQEKVSAVFYTLVIPMLNPLIYSLRNKDVKEAAQKLMLGKRNAC", "length": 312 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AIA3-1", "protein_name": "Uncharacterized protein", "gene_name": "ENSRNOG00000065493", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MIFVPFFPHPGSIRKDGVVYAHTMENSSNSPRETREPAPLRRTWRGCFQRALPRVSKFFRRGRGSTGGWDNGSPRQGPMHSDQDLRHLRSLLSKESCPVMSK", "length": 102 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AK52-1", "protein_name": "Olfactory receptor", "gene_name": "Or9s14", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAIEVHRNGSLSAMSLQGFVLLGFRGGAETQALLFTVFLVLYVVTVLGNLTMIMVITLDARLHSPMYFFLKNLSFVDLCLSTVVVPNALASIFFSSKTISFAGCATQFFFFSLLAATEAVLLAVMAYDRFMAICSPLRYPVTMCPMTCVRLVLGTFCVACLNSIVQTSLTFRLPFCSSNRIDHFYCDVPPLLQLACASTALNELVMFGICGFIIVCAVFVVIISYVYITVTILRMHSGSGRHKLFSTCGSHMTAVSLFYGTGFAVYGQPGGVASMEQGKVVSIIYILIIPMLNPLIYSLRNKDVKDALRRLGQRHSLAKESG", "length": 322 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AMC4-1", "protein_name": "Retinoic acid early-inducible protein 1 domain-containing protein", "gene_name": "ENSRNOG00000068014", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MCVFKNAWGHRNMCSMALCSQFGTHLHVSLTDAHSLSCNLIIRSPTKAEPLRYEGHCSMDEIVFLSFNNVNKTMPLGNQEKMANATKVQKCLTQWIDLLGQDLRDKVSEIKVHTTKTSGHPTLRVTMLSKHRHGEIIGASWEFNISENYSFILDLKTMKWKPQDIMKEWKDDETLMKHLNLSIVECSQKFNEFLNQHEERTSRYYLDSALPPAPPPLFKGFTILLWHSYTPAISPTSSDTHSSFINFRDGLIDINFPL", "length": 258 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AMN7-1", "protein_name": "60S ribosomal protein L7a", "gene_name": "ENSRNOG00000070681", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLKGKKAKGKKVAPAPAVVKKQEAKKVVNPLFEKRPKNFGIGQDIQPKRDLTRFVKWPGYITLQRQRAILYKRLKVPPAINQFTQALDRQTATQLLKLAHKYRPETKQEKKQRLLACAEKKAAGKGDVSTKRPPVLRAGVNTVTTLVENKKAQLVVIAHDVDPIELVVFLPALCRKMGVLYCIIKGKARLGRLVHRKTCTTVVFTQVNSEDKGALAKLVGAIRTNYNDRYNEIRRHWGGNVLGPKSVARIAKLEKAKAKELATKLG", "length": 266 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AMX9-1", "protein_name": "Ribosomal biogenesis factor", "gene_name": "Rbis", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAKNKLKGQKSRNVFHIASHKPLKAKNKAKPVTTNLKKINIMNHEKVNRMNRAFVNIQKELANFSKSLSLKSVQKELHHEKEPANVDEATRLMAQL", "length": 96 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6ARJ3-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "Or8b101l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTLGNVSSVKEFILLGLTQQPELQLPLFFLFLGIYVVSVVGNLGLIVLIVLNPHLHTPMYYFLFNLSFTDLCYSTVITPRMLVGFVKQNIISHAECMTQLFSFCFFVIDECYILTAMAYDRYAAICKPLLYQVTMSHQICLLMTVGVYMMGFVGAMAHTGSMLSLTFCEGNIINHYMCDIPPLQKLSCTSTSINELVVFTVVGVNVIIPTLTLFVSYTLILSNILSIHSAEGRSKAFSTCGSYIIAVSIFFGAVLFMYFKPSSASVDGDKVSTIFYTILGPMLNPFIYSIRNKDVHVALRRTLKKRIFT", "length": 309 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6ATM0-1", "protein_name": "ELAV-like protein", "gene_name": "Elavl3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKDAGAGSCRYKGLGAAAVRPRARSAQRGPVGGREGGREERTHYPAPDRPDRGPAAEGRAAEISVGKSDFCGPRGAALRAPSTARPLPPSTCRQGSGRRSAHPQARVSSRPSRAPPPPSSPLRRPQSQTPGRDPGVSTRRPPRSARPPEPPSIRTAPAGHTRMVTQILGAMESQVGGGPAGPALPNGPLLGTNGATDDSKTNLIVNYLPQNMTQDEFKSLFGSIGDIESCKLVRDKITGQSLGYGFVNYSDPNDADKAINTLNGLKLQTKTIKVSYARPSSASIRDANLYVSGLPKTMSQKEMEQLFSQYGRIITSRILLDQATGVSRGVGFIRFDKRIEAEEAIKGLNGQKPLGAAEPITVKFANNPSQKTGQALLTHLYQSSARRYAGPLHHQTQRFRLDNLLNMAYGVKRFSPIAIDGMSGLAGVGLSGGAAGAGWCIFVYNLSPEADESVLWQLFGPFGAVTNVKVIRDFTTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGERVLQVSFKTSKQHKA", "length": 522 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AUS4-1", "protein_name": "Ubiquinol-cytochrome-c reductase complex assembly factor 3", "gene_name": "ENSRNOG00000062467", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQTAAGKTLAVVAVLGAGAGVGSILFALVTPGELQKQSMLQEMPERDSRRRNEAVRTKELVIATLKDAAATKGNVAWRRTGQLEGQGRMCGTKGTNKCSLPIKWISQLDI", "length": 110 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AWY6-1", "protein_name": "Uncharacterized protein", "gene_name": "ENSRNOG00000065059", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAKATKKSKNTTSDVEPSTSSAKSKKAKTCYQYQTRAGEKKSRWSGSDCSVNVQKTTKKAKRTLPRIAENNTSEKTVPPTKKTKRAKDEQLFGHYHRLMDEISTSTERGPEQSSTDSSSASTSDEESQ", "length": 128 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6B5G4-1", "protein_name": "protein-tyrosine-phosphatase", "gene_name": "Ptp4a1l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MARMNCPAPVEVTYKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCKATHDTTLVEKESIHVLEWHFDDGAPPSNQIVDDWLSLVKIKFPEEPGCRIAVRCVAGLGRAPGLVALALIEGGMNYEDAVQFIRQKRRGAFNGQQRLPLEKYHPKMWLRFKDSNSHRNNCCIQ", "length": 173 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6B646-1", "protein_name": "Ankyrin repeat domain 66", "gene_name": "Ankrd66", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRSREARLHHQTPGDQEAGAACLLSWGGGGASFHGVNTLTLRPAMMACSTELLKDTDSVMELSKLSDMTKLHQAVAAGDYNSVKKILKKGLCDPNYKDVDWNDRTPLHWAAIRGQMEVIHLLIQYGARPCLVTDVGWTAAHFAAESGHLNVLKTLHALHAAIDAADFFGDTPKRIAQIYGQKDCVDFLDTAEPECRDHRQRGLLFDERDPDWDLKKRELELSLPVPDQNTNKKKKRIRGSTRVNHSKAWRI", "length": 251 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6G1V0-1", "protein_name": "Ankyrin repeat domain 62 like", "gene_name": "Ankrd62l", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSRVAGLSSKKSRWLLQSLLDQQRHSLGTGFESANILLSPKYHLKDKDLRKIHKAARDGDAARVQQLLLGKHCVNDKDKKKRTALHIACAYGHPKVVMALVEGKCEVNATDSEECTSLVKAVQCQEEECATILLENNADPNIVDAQGNSALHYAVYYKNTSLAAKLLDHEVNIEATNKDGFTPFLLAVSENKLKIAKFLLMKNASIHAADNQKRTALMHAVSHDSTNLVRFVLEQGVDLFVKDAFGLTAIDYAADFKYNSNMEILLEYKAKRYEESERANLVEKSSEEDSSRRKDQQSQELENMEKEELTEPGNGTEEQEPDGGVTSVEEPRRLDDRGDDQPQEAVTAPRTREKEQELPFTDMCTVVTGKEDEDESSWDSESVSENLPLIRIGVDGLLLVNGQAVENPEKYLHWLHNRKGEESVPNETKGVGDLQAFTPAEPGLELTSEEKHEELSRNEDCQPQVEEERTQEWSGWGAPEALCAAALDHGDIGSPLTRENGHPRARQSPSVDSEEQDGGSGLNIKEEKTRDHEEWSGDFLMDRTSKESEPAAGDLLQVKDSWSLNDTDPNKGSPAKRKSKEKHKVRGEMNAMEDADDFTPLSESCSDNKAELCCNTHQAETETESCELLTRQTGNMEGGVAGEVLKTEPARSREALKETEETGEGARVKMQLPGKDELYSEDAERQQYDMALSALHLKTKQTVRQLQETQDRQREVVRSSQRMQDHLQKLQAGCSEAEAMVQEQGKKTAELQKLHAGMIHELKEKWETIASKYLPLNIQLKYLEQELLSIKIAQKQYEKLHEDQRTLQRDAVDLQHQVQENMAKLDDEKQAMALRDSNNDSLMSQVELRIKNLESNLQKLQAEKESNERNVEKYLQRYIRERELSKTLSHTLHRTNSKLSRVRTDILLVTERNRTVQNTLTTRPVPKSPGVTEHSAYVNRNPNFIASRNLEAAMSSPQPSPELMRRRLLKKQKNMVKNITEEVDKAAAELESWSLEAYPSGSK", "length": 1003 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6G430-1", "protein_name": "Large ribosomal subunit protein eL24", "gene_name": "LOC689816", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLETCRNLSAIGYIWEDNSTEEYCKSSRRHGRPTSVTMKVNLCSFSGYKIYSGHERLYARTDGKFSSFLMPNVSPHSFPKGTLGKLTGLSSTEENTRKDSRKKFKRKEPTLQKFQRAITGASLADIMAKRNQKPEVRKAQQEQAIRDAKEAKKAKQASKKTAMAAAKAPTKAAPKQKIVKPVKVSAPRVGGKR", "length": 193 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6G808-1", "protein_name": "Paired immunoglobulin-like type 2 receptor beta", "gene_name": "Pilrb2l7", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MARILLLLLSAACLHTGNSAGYPKKYDYGVDQPAVLSGVQSGSIEIPFSFYFPWELAKDPQMRIAWRWKVFHGEFIYNSTQPFIHEHFKGRLIMNWTQGQTSGVLRILNLKENDQATYFSRVFLRTTEGMKSWQSIPGTQLIIHALITTPGSPSIIPSAVPTTGLEDTRGQRTPSLLNLGAMVGMVVSKVVVIIPLYGWVIFLWWKQRTQFRRDLVSEHPWKNFVPILPAESSSFL", "length": 236 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GB91-1", "protein_name": "Olfactory receptor", "gene_name": "Or4c117b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "TNRYYFNIFMIIMQNQSFVTEFILLGLSQNPNVENILCVVFLFIYLATIGGNMIIVVTIIYSPALLGSPMYFFLIFLSLLDACTSSTVTPKMIVDFFYERKTISFECCMTQLFAIHFFTGIEVIILSAMAYDRYVAICKPLHYSSIMTQRLCGILVIVSWAGGFLHSIIQIIFTLQLPFCGPNVIDHYLCDLFPLLKLACTEPHIFVILVFSNSGSISIIIFSILLVSYGIILFSLRAHSSEGRRKALSTCGSHITVVLLFFVPCFLIYARPTSAFSSEKNAFVFATIITPLLNPMVYTFRNKEMKNAIRKMWKRLIMVSCNY", "length": 323 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GF85-1", "protein_name": "Ceramide-1-phosphate transfer protein", "gene_name": "ENSRNOG00000064148", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "HFFLEYLNNLKIMLIFLSPPTGGWASDHHSPTTGTHLRFLNSLGAAFSFISKEVVSKLQIMEHPRSSPQSEHCSSLQSMAAYEVSNKLLDLARRSGPLHSNSGCRTVLCLHRALHWLQLFLEGLRTSSEDARTSTLCTEAYSAMLCAYHSWIRQAVTVAFCALPSGKVFLEMLGEALPFMEQMCDISQFYVEHFLLDLP", "length": 199 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GFV7-1", "protein_name": "Olfactory receptor", "gene_name": "Or1f21c", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSTNQSSVTEFLLLGLSRQPQQQQLLFLLFLTMYLATVLGNLLIILAISTDARLHTPMYFFIMILSFTDVCFSSTTVPKVLANYMLRSQTISFSGCLTHLYFLCVFADMDNFLLAVMAYDRFVAICHPLHYTTKMTNKFCVLLIVGSWVLTNLNALLHTLLMAQLSFCGDNIIPHFFCDATPLLKLSCSDTHLNDLMILTEGTMIVVTPFFCILISYIHITCAVLRVSSPRGGWKAFSTCVSHLAVVCLFYGTIISLYFNPSSSHFAGKDMAGAIMYTVVTPMLNPFIYSLRNRNMKGVLRKVLILRFPSKQ", "length": 313 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GGC1-1", "protein_name": "Histocompatibility 60b like 1", "gene_name": "H60bl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAKGATSKCNHSLTLSLLVLLNSLGTMQVDGTDSLSCNFTVQYKVSLGQCSVNGMTVLCFDDVRQNSPVCKTEKKGNATKLCNDLNQCLSYSFYEMMKLESGLFESKGNHTLRVTVQSQYNQGEFMDGCWAFMIDRQYPFYFYPKNMTWRENQPNAIKTMSQWENNRELFQSLKFLSTGDFSLCLKKLLTDSRELTRSTIKAPDTTQPTSTTQSPSTGNSTPAMSSNQSPSTGNSTQPTSTTDYLIVFEFTAIFLALIVVSMEKKKVLPAAPLPLQYELQSPSPAVLEES", "length": 290 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GIM2-1", "protein_name": "Olfactory receptor", "gene_name": "Or4x11c", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MADLFNVTEFIFLGLSPNKEVQRVCFVLFLLLYMAIVLGNLLMVVTVAVSRNLGSPMYFFLSSLSFVEICYSSTTAPKLILDLLAEMKSISVWGCMTQLFFLHYFGGIEIFLLTVMAYDRYVAICKPLHYTSIMNRKVCIVLVGTAWTGGFVHSFAQIVLIFPLPFCGPNTIDHYFCDVLPLLKLACSDTFLIGLLIVANAGTLSVIIFVVLLASYVVILFHLRTLSAEGRRKALSTCGSHVTVVILFFGPCVFIYSRRSDTLPVDKMIAVFYTVITPLLNPLIYSLRSAEVKKAMKNLWFRTMKADEK", "length": 309 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GJN1-1", "protein_name": "Heterogeneous nuclear ribonucleoprotein A1", "gene_name": "Hnrnpa1-ps20", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "LSQSPPRNRTEQLWKLFIDGLSFETTDESLRSHFERWGTLTDCVVMRDPNTKRPRGFGFVTYTTVEEVDAAMNARPHKVDGRVVEPKRAVSREDSQRPGAHLTVKKIFVGSIKEDTEEHHLREYFEQYGKIEVIEIMTDRGSGQKRGFVFVTFDDHDSVDKIVIQKYHTVNGHNCEVRKALSKQEMASASSSQRGRNGSGNFGGRGGGFGGNDNFGRGGNFSGRGGFGGSRGGGGYGGSGDGYNGFGNDGSNFGGGGSYNDFGNYNNQSSNFGPMKGGNFGSRSSGSYGGGGQYFANPRNQGGYGGSSSSSSYGSGRRF", "length": 319 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GJR0-1", "protein_name": "Aspartate aminotransferase", "gene_name": "Got2-ps6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALLHSRMATTFHPGLAAAASARASSWWTHVEMGPPDPILGVAEAFKRDTNSKKMNLGVCAYRDDNGKPYMIPSIRRQRPRLLEKIWTKNAYPSGDWLVFVRLLQRSEPVFCKDILSLAKMSFYPNHPGETTRPSSGMPACSYKVIDTMTHKTCGFDFSGALEDISRIPEQSVLLLHACAHNPMGVDPRPEKWKEMVSVVKKKSLFAFFDMAYQGFASGDGDKDAWAVQHFIEQGINVCLCQSYAKNMGLYGERVGSFTVVCKDEEEAKRVESQLKILIRPLYSSPPLNGARIAATILTSPDLRKQWLQEVKGMADRIISKRTQLISNLKKEGLFHNWQHITDQIGMFFYMIKDGRISVAGVTSGNVCYLTHAIHQVTK", "length": 379 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GL73-1", "protein_name": "Uncharacterized protein", "gene_name": "LOC134481331", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "TALLVSLPEQNLAMARILLLFLSAACLHTGNSSGYRRVNDFGVNQPAVLSGVQSGSIEIPFSFYFPWELANDRSMSIAWIWKYFHGEVIYNSTQPFLHEHFKGRLIMNWTQGQTSGVLRILNLKENDQARYFSRVFLRTTEGMKSWQSIPGTQLIIHALNTTMGSPSIIPSAVPTAGLEDKRGQRNPSLLNLGVMVGMVLAKVVVIIPLYGWMIFLWWKQR", "length": 221 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GLF3-1", "protein_name": "Heat shock protein 90 alpha family class B member 1, pseudogene 13", "gene_name": "Hsp90ab1-ps13", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPEEVHHGEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLWELISNASDALDKIRYESQTDPSKLDSGKELKIDIIPNPQERMLTLVDTGIGMTKADLINNLGTIAKSEDQTEYLEERRVKEVVEKHLQFIGYPITLYLEKEREKEISADEAEEEKREKEEEDKEDEEKPKIEDVGSDEEDESSKDKKKKTKTIKEKSIDQEELNKTKPIWTRNPDDITQEEYGEFYKSLTNAWEDHLAMTSLSGYVSRMKETQKPIYYISGESKEQVANSAFVERVWKRGFEVVNMTEPIDDYCVQQLKEFNGKSLVSVTKEGLELPEDEEEKKKMEESQTKFENLCKLMKEILDKKVEKVTIPSRLVSSPCCIVTSTCGWTANMERIMKARALRDNSTMEYVMAKKHLDINPDHPMVETLRQKAEADTNDKAVKDLVVLLFETALLSSGFSLEDPQTHSNCIYCMIKLGLGIDEDEVTAEELSAAVREEIPPWRVMRMPLAWKKWIKGSWEAPALCIVSLGLPQQP", "length": 518 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GM54-1", "protein_name": "MAGE domain-containing protein", "gene_name": "Mageb11l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPHDQKSKLHSRENSYQAGGGAQAYGDAEEIAEAAAEAAEESSAKSQSQPGAEYSRNHRAPPKAKPSAKLILSSSSSESDESSHEESEPSVQKDRPFLHQDLIERRVAILLQYLLHNYNLKQLTTKEEMLKVITKKYEKDFPEILRKASEKLEDAFAVEVREVSSSQPSYDLISKLKLPNNGRIRAGKGLPKTGFLMSILGIIFIQGNSASEEDIWKILKKKRIYPGKKHRVFGEPRKLMTQYLVKLKYLEYRQVAHSDPPRYEFLWGPQAHAETSKMKVLEYLAKINKTTPHAISALYQEALKDEKERAEVRDEDNTDTTDQSTEGSPEKSPTASTTPVDT", "length": 342 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8J8YII4-1", "protein_name": "Coiled-coil domain containing 188", "gene_name": "Ccdc188", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEGPEPLGPCGHSHTQHPPAPVSNNHGGCLNQPCQGFVRWPCLVPLQSTQSLESSRPFPAPGTGSGGPRMRGEAPGMFLSSEGEIPRQRAREPAGARQEEVEVEWDWPLHPGHEQGPPRQTAPPTSGPRPCPCPTLPPRGRATASSRQAPTQLQGGTLESAQQSFLQLEQENHSLKRQNQDLREQLGALLGPGQQFLPLCSEHSSCTALAWVSGNTRSRTHAAAPPAVHSLGPDPGALPQSPESARTRLLEDRAPVQLLRQQELCPGKESFVRQSQSELQQIRLSFERKKMAITEVWDGVAEVHMALNNQATGLLNLKKDIRGVLEQMEDIQLEILGERAQCRTQARKQQQMMEAAGLEAAAGCSAGLHSGLRVRGGPHTLRGAGATPAEPSQRLEAQGLTGSLLTPGGGRLPAFLEQKPSGPSKEARWLVLPQGLRGLTGPCLQHCGTWPLPEAAEKGGGRASPEGWACSWIYSHDTLCM", "length": 481 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8M9PVG7-1", "protein_name": "5-hydroxytryptamine receptor 7", "gene_name": "htr7a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MVLGDTNRTIIAKSHGETMKSLMAEERARETGASVETFNGIMISEVLVPRLFKIAHESGEVAVAAGSGSMDMKPSSSPILLEMMEVANGTRCAEQILSYGEVEKVLIGGVLTMLTLITICGNMLVVISVCFVKKLRQPSNYLIVSLALADLSVALAVMPFVSITDLIGGRWIFGKFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGWCMAKMVLSVWLLSASITLPPLFGWAQNVNDDRVCLISQDFGYTIYSTAVAFYIPMTVMLVMYYRIFRAAKLSAAKHTITGFPRVEQEEVEEDEVEEDGGDGAEEPTGVDCVTVAIKLQREVEECARLPRILRGVGRRCSDRRSISIFKREQKAAATLGIVVGAFTICWLPFFLLSTARPFICGTECSCIPLWVERTLLWLGYANSLINPFIYAFFNRDLRTTYRSLLSCRYRNINRRLSAAGMHEALRLVERPEVVVSG", "length": 479 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9QGZ8-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "pimr118", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLFTVLGVIALFLRERDTNNTEEEVQNDVPPVRNSDGQEIDDWCKEPSLLEPVSVHSEEPSLEEPVSAHSEEPSLEEPVSVHSEEPSLEEPVSVHSEEPSLVEPVSVHSEEPSLEEPVSVHSEEPSLEEPVSVHSEEPSLKEPVSVHSEEPSLVEPVSVHSEEPSLEEPVSVHSEEPSLEEPVSVHSEEPSLEEPVSVHSEEPSLEEPSLDLSFFSAESSWSEDLSSSFLTVESSWSDDLSSGFLTAESGCGDDEPLFVDSAEPEKLKEDKETQIIEINSHCYAIEAQLGEGGCGAVFSATRLEDGLQVAVKLSDFEEEKRFISVDGFEDPLPLEIALHFLANKGPKVKEIIELLDWKVEADRYFMVLEQPIPCMSLHEFLLDCEGIIPENKLRTIMYQTTVAAQTCCQRGVLHRDIKLENLLINPDTLEVKLIDFGCGDLLTEDSFQYFRGTREYFPPEFSSTGRYHGEPATVWSLGVVLFLLVFYRFPEQSDLPRMNNRRLRIKGLSRDCCDFFHGCLQLDPKDRLELQNLSSHKWIRTRTRRNDENCPNLTDGSSHSNHPITSN", "length": 567 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8V0WZU8-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "CHIR6B2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAPMVVNLILGWWLVAVSRAQKLPRPSLSLHPSQGASLGDNVTLRCHLPQPAAWVRLYRYQNPTYIEQKDNVQDMAEFSLTSIKQEDAVIYQCQYQGLAPAGTSQKSDPMELLVTDHRYPPPGISLSPKEHVEMGSNITIQCWNKDYGASFLLHKGGHSAPIQHQEPDYWGTATFTLFGVTPADSGTYRCSYRIGGCCLLFSPLGDNVTLEVIPRPAPPGVNGGPSRNLVAAVAGGCAAAIVIITVSFLLVALRRQMQRAERPGATPRSPEAVQFQVSPGDSEGLTYAQLQAVTPSTHPPTSSTTPEPPIIYAEVGTRGPR", "length": 321 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XEA0-1", "protein_name": "C-type lectin like 8, MHCY region", "gene_name": "YLEC8", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MQSVQIPILKHKVSTPAEGERLNHFSEHKAAPEPTAHQRRRIPTSSDPQLPEEDVQILLLESNTSTPAMGEGDQQETFSEHQAAPEPLGQSGGHQWGSWCHGMGRRRSCVQLIAVHAALGALILMLVVLVISTVCRRAPIPPFSAFGHACPNAWVGFQGKCYYFSKEENDWNSSREHCSAHGASLATIGSAEEMDFMMRFQGPANCWIGLHREEEDAQWTWSDGTAFTNWFELRGGGRCAYLNGDRISSSLCHLHKHWVCSRADHYVLWKQKVHPQ", "length": 276 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XED4-1", "protein_name": "C-type lectin like 18, MHCY region", "gene_name": "YLEC50", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MQSVQIPILKHKVSTPAEGERLNHFSEHKAAPEPTAHQRRRIPTSSDPQLPEEDVQILLLESNTSTPAMGEGDQQETFSEHQAAPEPLGQSGGHQWGSWCHGMGRRRSCVQLIAVHAALGALILMLVVLVISTVCRRAPIPPFSAFGHACPNAWVGFQGKCYYLSKEENDWNSSREHCSAHGASLATIGSAEEMDFMMRFQGPANCWIGLHREEEDAQWTWSDGTAFTNWFELRGGGRCAYLNGDRISSSLCHLHKHWVCSRADHYVLWKQKAHPQ", "length": 276 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XEJ6-1", "protein_name": "Sulfotransferase", "gene_name": "LOC769841", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MVCRAAAPNSHPSTMPVHYVTYKGIKFPPAYNSVHSLSFAHNEFLVRDDDVFNITYPKSGTVWMTEILSLIRSHGHPSWNQTVLNSDRMPWFSTRLGLEAALSYPSPRLLTCHLPRHIFPKSFSHSTAKVIYTLRDPRDVVVSYFYFCKMCNSYEDPVSFEQFLRDFLSGELPHGSWFEHVRGWMQMKDRENFFFITYEELKQDLQGSVRRLCHFLGQNLDDDAISSVVQNASFMAMRQNPMCSSILLPADIMDQTKGQFLRKGICGDWKNHFTVAQTETFNRIYLEKMRGLNVAFPWDRDQDPDLTEQ", "length": 309 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XGU1-1", "protein_name": "C-type lectin domain-containing protein", "gene_name": "YLEC62", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MQSVQIPILKHKVSTPAEGERLNHFSEHKAAPEPTAHQRRRIPTGSDPQLPEEDVHISVLESNTSTPAMGEGDQQETFLEHKAVTEPLGQSGEKPQWGSRCHGTGRRRSRVQLIAVHAAVGALILMLVVLVISTVCRRASIPPFSAFGHACPNAWVGFQGKCYYFSKEENDWNSSREHCNAHGASLATIGSAEEMDFMMRFQGPANCWIGLHREEEDAQWTWSDGTAFTNWFELRGGGRCAYLNGDRISSSLCHLHKHWVCSRADHYVLWKQKVHPQ", "length": 277 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XGW1-1", "protein_name": "NHL repeat-containing protein 3", "gene_name": "NHLRC3", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAAPAVLWRLQRLSAAERLEARLSGAVRKEPGRGEARQSEKKPHSPHCPLRCSYACPGRTPMTSESGRKALSHLGRQQQCLNKMAELRARLEAFPAPECLFKTLNPFMGFLRLFFAPQPLGGEQALFRAAQCAEASPRIPAPQAWAGRSRGCHGNAARPASMGRKQAVGPRLVMAGALLTLLGLLWGSQMLKAFDYFSSWKGDGEQQMYKLDISWPKIPEYFSGQTFCVAVDSLHGLVYVGQRGDDIPKVLVFSVEGYFLYSWNDTVEMPHGIFVLNTATDSSVWITDVGSGKYGHTVKQYSPSGKLLQVLGTPGNAGSSLNPLQFDQPAEIFVEESGEMYIVDGDGGMNNRLLKLSQDYKEIWLSGENGTGIGQFKIPHSVTVDPFGRVWVADRDNRRIQVFDKVTGEWLGAWSSCFLEDGPYSVRFTGNYKYLIVAHLNINRLAILAAPPVGEIGDCAIVSTIQLADETKPHLVDVDVKSGAIYIAEIGAQQVQRFVPLS", "length": 502 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XPN1-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "CHIR2A13", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAPMAVALILGWWLVAASRAQQLPRPSLSLHPSQGVSLGDNVTLRCHLPRPAAWVWLYLEGRWSYAKYIDKKQDTTEFSFLSASHDQAGTYLCQYQVSESEDVSVTSDPVKLVLTDRSFPPPHISLHPEERVGTGTNVTICCWNKDYGATFLLHKDGRSDPIQRLVPDDVGAVSFTLFGVTPADSGTYRCSYHPKNYPFLSSPLGDSVTLEVTPTPAPPGAELVSRGNLVVAVVRGCAAALIFGLGVFFVIDARSLWIRRDESLGGEGI", "length": 269 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XPP6-1", "protein_name": "SUN domain-containing protein", "gene_name": "LOC776146", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEQQGHGERGNWQTKVWKTVALVLVTVAVASFGVYCVGGLVEGIKTTAGVTARLVRRDGEIVSLDEELAKVQRQLHVLQWRARDITERALHEALRRTELPGFTGEAVQKIIHQVLEKLEESPFQMTNYASKTSGAAIVRSKTSPSWIGSGRVFWQSLPLVAYMRPPEVILEPDNHPGNCWPFPGSQGHVFIKLPVAVFPTAVTINHGVPAAAYHADSISSAPKDFAVYGLQEEDDETGTLLGEFIFMPGQAPGQTFQLKNEHSAFIKYVRLQVLSNWGHPEYTCVYQFRLHGDPAPDGDARGKLSA", "length": 306 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XQE0-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "CHIR6A8", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEPMAVNLILGWWLVAGSRAQQLPRPSLSLHPSRGVSLGNLVTLRCHLPRLAAWVWLYRGGGWSYKKGKKKEQDAAEFSFASTLREHAGRYRCQYRVYESAEVSVESDPVELVLTDVRYPPSSISLQPEQHVGTGTSVTIHCWNKDYGATFFLHKDGSSDPLQRQDSSGGGTATFTLFGVTPADSGTYRCSYRHWRYAFMSSPLGDSVMLEVTPTPAPPGAELVSRGNLVVAVVRGCAAVLIFALGVFFVIDARSLWIGRDESLGGKGI", "length": 269 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XTD2-1", "protein_name": "Coiled-coil domain containing 97", "gene_name": "CCDC97", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MKEDPKEAEGPTASKWIPIASNGNPTASKWIPIASNGDPTAPKWVPISSNGDPNWVPISSNRDPMASKWIPVSSDRDPTVTKENPPSSNETPAAEWDPKVPPEGRPVEEGDPKASPTEDPPAEPDPKASNCAPLSSHWAPEAAVWDPTSPHRDPTAEPQCSASPEQHRAAQRDPASPMEEDRYPATHGVRPATRADPAPYGDHPEAEEDPLPAAVEAMLAAVAASPVRVRSQQQGDPELTAAERRRDLRALFLRKPLVFLERFHGALQAEHLPCFAHLPPRYEVAFYCRQVRARRQQNPQTGLSRWPRRPGARTRLRNRRYAALRQLIAGGEYFSEEEMRAREPLLYEHYIGQYRDAETPPGTPPCPPHPGTPPGTTWAAALLRSVEEAAVQQRLQRQRLREGDSGEEDEDEDEAEEPHIPDAGELEVLREEFRSRMYQRFLDGEDRDFDYSQVDENPDMDNLDIESRDAEERYFDEEEPSAAPQLE", "length": 487 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0Y889-1", "protein_name": "Transmembrane protein 65", "gene_name": "TMEM65", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSAWLGRAVLLLGRPGGPAAPSSSSRLCSLRGPPRCCCRRRLSSLRGGADGLLPARGAPPGRALGTHPKKEPMEALNTAQGARDFIYSLHSTERSCLLRELHRFESIAIAQDPIAARASCQQYGETWAHQEPSGACSSVHSQAYHQKEAVPSSNCPSTKYDRTHYLWPPLMAEAAGKPGRCPHCCAEGWSSEKLEVAPPSPGQLRHVFFHNALPFVGFGFLDNAIMIAAGTQIELSIGVVLGISTMAAAALGNLVSDLAGLGLAGYVEALASRLGLSIPDLTPKQADMWQTRLSAHLGKAIGVTVGCILGMFPLLFFGDEEEKLEEKN", "length": 328 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0YA34-1", "protein_name": "SWIM-type domain-containing protein", "gene_name": "LOC100859602", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAERGQLPPYAKRLCCRPGYGSGCRLGQQAGDTGPGSGTFCAGPSSAAAAAAAAAAATAASLVLLPLGKTQSPESLLDIAARKVAEKWPFQRVEEQFERIPEPVQRRIVYWSFPRSEREICMYSSFDTGAEGFTAPGSAAGNTASGGAVDAVADENRLPFRRGMALLDGGCVDNVLQVGFHLSGTVTEPAMQSEPETVFNVAISFDRCKITSVTCSCGNKDIFYCAHVVALSLYRIRKPDQVKLHLPISETLFQMNRDQLQKFVQYLITVHHTEVLPTAQKLADEILSQNSEISQVHGAPDPTAGASIDDENCWHLDEEQVQEQVKLFLSQGGYHGSGKQLNLLFAKVREMLKMRDSNGARMLTLITDQFMADPRLLLWRQQGTAMTDKYRQLWDELGALWMCIVLNPHCKLEQKTSWLKQLKKWNCVDVCPWEDGNHGNELPNLTNALPQGANANQDSSNRPHRTVFTRAIEACDLHWQDSHLLHIISSDLYTNYCYHDDTESSLFDSHGWPLWHEHVPTACARVDALRSHGYSREALRLAIAIVNTLRRQQQKQLEMFQARKKELLYRGITSITNLEGWVGHPLDPIGTLFSSLMEACRVDDDNFHGFSDFMENTSQHKSLEYQHLPAHKFLEEGESYLMLAVEVALIGLGQQRIMPDGLYAQEKVCRNEEQLISKLQEIELDDTLVKIFRKQAVFLLEAGPYSGLGEVIHRESVPMHTFAKYLFTSLLPHDAELAYKITLRAMRLLVLESTAPSGDMSHPHHIASIVPNRYPRWFNLSHIESQQCELASTMLSAAKGDVQRLETVLQSIQKNIHSSSHIFKLAQDAFKIATLTDSLPDITLLKVSLELGLQVMRMTLSTLNWRRREMVRWLVTCATELGVHALDSIMQNWFTLFTPTEATSIVATTVMSNSTIVRLHLDCLQQEKLAGSARTLALQCAMKDPQNCALSALTLCEKDHIAFETAYQIVLDAATTGMSYSQLFTIARYMEHRGYPMRAYKLATLAMTHLNLSYNQDTHPAINDVLWACALSHSLGKNELAAIIPLVVKSVKCATVLSDILRRCTLTTPGMVGLQGRRNSVKLMSLDKAPLRQLLDATIGAYINTTHSRLTHISPRHYGEFIEFLSKARETFLMSHDGQIQFTQFINNLKQIYKGKKKLMMLVRERFG", "length": 1168 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0YDY5-1", "protein_name": "SKA complex subunit 1", "gene_name": "SKA1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEAEGLEALSRHLAAKIGLIKRLLQLRGLGRREMLAEVGMEVAVLHGLLGRMEEEVNQRRQLAAALQEMRKRAEKEKWEAERLQLVKKAAKEAPLVNDAPLISDEEFESVPGYMRGRLTLAQTNAALRALHAAAASKYRLLRHPPKSLPSSSRALCHRFREEETKETQGLTFVVEADLKEFTQLKVDRTFHRIVGVLRHCRRLREVRGARLVRYVLP", "length": 217 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0Z0M2-1", "protein_name": "Tumor necrosis factor ligand superfamily member 10", "gene_name": "TNFSF10", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MLPAGGPSPAHTCGAVLVAAVLLQSVCVAVTYIYFTNELKQFANADLVHSCERGHPLSPPPPPDVPQTAVTRPTKAEGGAAPVGASCSIGQSRRAQSDLRQRAANAASPQHGPPCAARSRARCSCPRCTAGPRVCRRTQQKLWDTYSRSGTACLTGEELGDLIQNLDVVESKDRVADPCWQVKWHLGKLIKKMMSRILQENMSAINGDRTQALPRRDEPPQGPTLRIAAHLTGSSKRSSASPHIDYLSYRGIGHKIHSWESSRRGHSFLYNVELWNGELVVPQTGFYYIYSQTYFRFRENEDEDSGLLERIKNPKQLVQYIYKLTNYPDPILLMKSARTSCWSKKAEYGLYSIYQGGVFQLKREDRIFVSVSNSDIVDMDKEASFFGAFMIS", "length": 392 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0ZCD9-1", "protein_name": "Mab-21-like HhH/H2TH-like domain-containing protein", "gene_name": "LOC124418390", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MALVLVLALLVRALIVSGSDHAVMLERVQQHEKEQRNGEQSWVDMSALLFTLLHYWKIWFCTGLFVFLFWNMWRSLKRKQHEEGGQQEQQEREEQVEEVEREEQQEQVEEEEQLERVEELEQEDQVEHVEQEEQEEREDQGEQVQQEEQVEEVEQEDEEEEYFHHSALTRYIARRAWEKMQGKATKCVLVEELMSDLLQTYTFVCSNSFYPVLQPAIGVGSAFEGWSPCEEDIVYRLLVPIKAPHGHVFHPELGEEGEVLARNSRIRVELVCMCTREQQLGDVLCFLHHSEEELSQNQQPSLLQTLCTGSYLDVQKTAAWFNKQVPRTWRLTHRAHRYGLKVLPSSRSCKLQVTDTSSGEKVHVELLFGVQQGNLDIFLSSQNAEAVFTPSTTWPQSCAVAERKYFEYVARTAGPNSCHLVCLRLFAHILVGMGFSTYAIKTLLLHLLAIIPLEDWRRRHFLSRLENLLQYLQYCLNDKVLNHFLLGNATMPDEVVLPQAFQTASPLNLFQHLEQDPDAHSRVLRDFKELKDRLFRLLLFGR", "length": 542 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0ZD85-1", "protein_name": "Mab-21-like HhH/H2TH-like domain-containing protein", "gene_name": "LOC124418382", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MALVLVLALLVRALIVSGSDHAVMLERVQQHEKEQRNGEQSWVDMPALLFTLLHYWKIWLCTGLFVFLFWNMWRSLKRKQHEEGGQQEQQEREEQVEEVEPEEQQEQVEQEEQLERVEELERVDQVEHVEQEEREDQGEQVQQEEQVEEVEREDEEDEYFYHSALTRYIARRAWEKMQGRATKCVLVEELMRDLLQTFTFVCPNSFYPVLQPAIGVGSAFEGWSPCEEDIVYHLLVPIKAPHGHVFHPELGEEGDMLARNSRIRVELVCMCTREQQLGDVLCFLHHSQEELSQNQQPSLLQTLCTGSYLDVQKTAAWFNKQVPRIWRLTHRAHRYGLKVLPSSRSCKLQVTDTSSGEKVHVELLFGVQQGNLDIFLSSQNAEAIFTPSTTWPQSCAVAERKYFEYVARTAGPNSCHLVCLRLFAHILVGMGFSTYAIKTLLLHLLAIIPLEDWRRRHFLSRLENLLQYLQYCLNDKLLNHFLLGNATMPDEVVLPQAFQTASPLNLFQHLEQDPDAHSRALRDFKELKDRLFRLLLFGR", "length": 539 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0ZE07-1", "protein_name": "LIM domain only 1", "gene_name": "LIMO1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MVLDKEDGVPMLSVQPKGKQKGCAGCNRKIKDRYLLKALDKYWHEDCLKCACCDCRLGEVGSTLYTKANLILCRRDYLRLFGTTGNCAACSKLIPAFEMVMRARDNVYHLDCFACQLCNQRDSNPMGWYGSHPVTAAWEAEARTTSLGQPGVRAAELP", "length": 158 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0ZGC1-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "LOC124416945", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MVAGSPALLLLLSLGLCFTGAQGQGNTMAVSFLNRSMKHPKEGQRLGLECHTYKTSWGVSWIRLDKDGNLHFIVYISKFSSTTFPGNKGASSQFEVSKQGSSYRLTVKNFRAQDQGIYFCIANINQVLHFSSGQRAFFPVTTTTAAPTTLRAVTLTATTQSSQVTMKDISQHSPDPGRSKENMPNFCCKLVMWVNLACACLLLLTAITITTTHCQRPSSP", "length": 220 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0ZPB4-1", "protein_name": "trypsin", "gene_name": "LOC107049069", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MKFLVLVAFVGVAVAFPIRDEDDDKIVGGYSCARSAAPYQVSLNSGCHFCGGSLISSQWVLSAAHCYKSSIQVKLGEYNLAAQDGSEQTISSSKVIRHSGYNANTLNNDTMLIKLSKAATLNSYVNTVPLPTSCVTAGTTCLISGWGNTLSSGSLYPDVLQCLNAPVLSSSQCSSAYPGRITSNMICIGYLNGGKDSCQGDSGGPVVCNGQLQGIVSWGFGCAQKGYPGVYTKVCNYVSWIKTTMSSN", "length": 248 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V1A1Z3-1", "protein_name": "Bridging integrator 2", "gene_name": "BIN2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MPSLYHPNAIPVPFPSHPCTTLMSSLTHHIIPVPSSCLPNVIPIPYHPHVISTLSLLHPHFIPMAFLNLPHAIPVPPLIHSCAVPMSYHPFPISFSFPSPSHPSIAPMQSPSYPYPTPVPPPFHLLPIPIPTPVPPPCHSCSIPIQPRCRLHAILVPFPPHCHPHPVPAPSPPHPSAIPMPSHFHPHPIPVPPHTISIPSPPQCHLHAIPVPSPTHPHPIPSHPRFPHPLWAQGHPHPRGSNLSPPIPPPPPNTFALQNEGNKLYKDLKAFVGAVKVMHESSRKVAETLQEIYSTEWDGHVELKAIADSNDLLWDDYEAKLGDQALRLMENYLAQFGDIKERIAKRGRKLVDYDSARHHLEALQNAKKKDEAKIAKAEEEFNRAQAVFEELNRELREELPVLYGSRIACYVTIFQNISNLRDIFYKEMSKLNRDLYEVMGKLDKQHSSKVFIIKGVPSKRRSLLISAPVSPPAAYPCPGKAPNWDPSSGAEQTPTSPRVGSDATEDVPNGLAAPGPAEPGAPMPGPPPASPTSVRSASESESECSEESREIDLSPKEMEVSVGSGCPEYPKTEGAAKGEVEGIAASMASMIVSEAIAAATGAAPGDSDGVGGGDSTDSEISPAEGAWGGPSPGGSEERVEGTDVSPEVGSDAGPCEHGTPEPPQQDVSCDPPQDPSESLTPL", "length": 682 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V1AKD9-1", "protein_name": "Borealin", "gene_name": "LOC121107214", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAPARRKAAAGARGRKLSAFLKDFDREVRSRVEQLRTNGERLVKEMENLYDVELLRLPAALREMNWLEFFAKGGSQKVVEEAVTADLGITEINKLTAELIQTPLKIVTKEKSKQGIEATEEAAEVPLLPPAKKAKHDSQLLLEQAAASTNPRNGKVRTSTKKAPVSRSRRAPSARVKRVSKRSSKSSFITPATGRNLDLCARGGASIVTPRFDSRVFKTPGLRTPAVNERVYTISANGSPLADGNDVFITVPVGGGESIRLTASDLTKKNLLHLNPEARGIMKKLSVRLAQACSSAKTHR", "length": 300 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V1AMC7-1", "protein_name": "ODF3A protein", "gene_name": "LOC121107218", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MPASMDGAWVGTWRPHRPRGLISAQFPSPGPQYSIPGTTGYVGHSPTKARAPAYTFRGTKPPAAGSCGPGPCYFVEPAITRNGKYVAPGAQLRGRPVTKTTVTPGPSDYRTEAANRHVFKCPPVQSMAFRREPLRTDHPPGPGTYTLPRLMGPNTVYTSASPCYSVRGRSQRGRFDEDLAKTPGPAALPKVPVDAYKTRAPAYTMAARPKAGEGKAAKPGPADYSVGRVTLIKPQAPASTFGIRHSLYTTPLIVE", "length": 255 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8W4F7J1-1", "protein_name": "40S ribosomal protein S26", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MQPIHCTNCARCMPKDKAIEKFIIRNIVEAAAVGVISEVSVFAAYVLPKLYAKRHYCESCAIHSKVIRNRSREAQKVRTPPPRFRPTGAALRPPPKCM", "length": 98 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4F8K9-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258234", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRNHTVTTFILLGLTDEPQLKTLVFIFLFLTYMLSVTGNIISLTSTDSHLKTAMYFFLQNFSFLEIAFTSACIPKYLYNIATGDKTITYNSCATQLFFTDLFAVTEFFLLATMSYDRYVAICKPLHYVTIVNHTVCRRLIFGSWLAGLLIIIPPLSLGLKLEFCDSNVIDHFVCDAAPLLKISCSETWLIEQMVIVCAVLTFIMTLMCVVLSYVHILKTILQFPSAQQRKKAFSTCSSHMIMVSISYGSCIFIYVKPSPKDSLAVNKGVTILTTSIAPMLNPFIYTLRNKQVKQAFNDAIKRIALFSKN", "length": 309 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4F9E2-1", "protein_name": "UPAR/Ly6 domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "RLEFSSLSPAEVPLVAAAGGRGAFDMRCHECDTKNTFACDHIVTCPRGIRRCLTLSIRLSSREIYVYKGCTRNCTFIYADEQPPPGERKPPRSNSLYFVQCCNAITCNRGGPINLEKDITPPLILEEELGGTVRLGEATLFLSVASVLVSHALT", "length": 154 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FBC5-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLTHSFSFFSSSSSSSTYSSSYPLLPLLLQPQNQFRIWALKDYGQRNSTSLHDFILLGVVATFYLITLVGNTAIILASLLDSHLHTPMYFFLRNLSFLDLCFTTSIVPQMLLYVYMWLGSIECLLLAVMSYDRFTAICKPLHYLVIMNPHLCLKMIIMVWSISLANSVVLCTLTLNLPRCGNNLLDHFLCELPAMLKIACIDTTAVELSVFALGIAIVLTPLILILISYGYIAKAVLRMKSTAGQRKAINTCGSHLTVVSIFYGAIIYLYLQPGNSASKDQGKFLTLFYTIITPSLNPLIYTLRNKDMKEALKKLMRVDHKSTKSKRTWKS", "length": 331 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FBS2-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258626", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRNHTAITTFILLGLTEDPQLQLLLFLFLFLTYILSVAGNLTIITLTLLDPHLKTPMYFFLQNFSLLEISFTTACIPRFLYSISTGDRTITYNTCFTQLFLTDLFVITEFFLLATMAYDRYVAICKPLHYMTIMSNKLCKTMVVCCWLAALLIILPPFSLCFHLEFCDSNLIDHFACDASPLLKISCSDTWLIEQMVIACAVLTFIITLVGVVLSYIYIIRTILKFPSAQQRKKAFSTCSSHMIVVSITYGSCIFIYINPSAKEEVNLNKSVSLLISPISPVLNPFIYTLRNKQVKQALHDSLKKTAFLLRK", "length": 312 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FCJ2-1", "protein_name": "Histone H2A", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSRKRNLPQCNPPKKQALSRSSRAELQFPVSRVDRYLREGRYAQRLSSHTPVFLAGVLEYLTANILELAAGEAHSSRKMRIAPEHVQRARSHNETLSSLFQASSVSRGAEEEAEEPLPEAGR", "length": 122 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FD42-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTALNHTGVSHTVFYLLGIPGLEDQHLWISIPFFISYVTALLGNSLLIFIILTRRSLHEPMFLFLCMLAGADLVLSTCTVPQALAIFWFRAGEISLNCCITQLFFIHSIFVFESGLLLVMAFDRYVAICYPLRYTTILTHPLIGKIGVTIVLRSYCAIFPIIFLLKRLTFCRSNVLPHTGCEHIGLAKYACNDIRVNIWYGLFVIVSTLLLDILLIFVSYMLILHAVFHMPSQDARHKALNTCGSHVCIIILFYGPGIFTALTQRFGRHIPAHIHILLANVCILVPPMLNPIIYGIKTKAIQEQVALILFPKYR", "length": 314 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FH98-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "VCHYGNYYSGLSCSCGYGCGYSRCGCNCDYDKCGYRCGYGGYVYGCCHLSCCGRYRPYGFY", "length": 61 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FHY5-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "DTGSCGAIVLTQTPLSLSVSPGEPASISCRSSQSLEEYGKNWLSWYQQKPGQSPRLLIYQATNRASWVPERFSGSGSGTDFTLKISRVEAEDAGVYYCQQYKEFPPTVIQPLTQTPLLGAQLHTWLCVVWGAEGQKL", "length": 137 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FIZ4-1", "protein_name": "Envelope glycoprotein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRPTLSRRHLPTRGGEPKRLRIPLSFASITWFLTLTITPQASSKRLVDSLTSPKPLSLTWLLTDSSTGITINSTQREAPLGTWWPELHVCLRLVIPGLNTMSTPPDILRAYGFYVCPGPPNNEEYCGNPRDFFCKKWSCVTSNDGYWKWPTSRQDRVTFSFVNSYTSYNQFNYGHGRWKDWQRQTQNRQISCSPSDLDYLKISFTEKGKRENIQKWINGMSWGVVYYRGSWGGEGSILTIRLRIETQMEPPVAVGPNKVLTEQGPPIQGQRPSPNPSDFNTTSG", "length": 284 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FJ61-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSSTKNKHLMKGSKKGPKKKVADPFSKKDWYDGKAPAMLTKKRNIRKTLVTGTQRTKITSDGLKGHVFSSEPCQSAE", "length": 77 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FJT7-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MKNPEVRKIHSAVFLITYLSTILGNLLIVVTMVTSQSLRSPMYFFLTSLSLMYVTYSSVIAPKMIVDSFSETTAISLEGCMAQLFAEHFFGGVGIILIIVMAYDHYVVCCLLLGGAWVGGSIHATIQLLFICQTPFCGPNVIDCFMCDLFTLLKLACMDTHLLGILVILNSGVMCMAIILILITSYVVILCSLKSYSFEGQHKALSTCGSHLIVVVLFFVPCIFLYVMPVATYPIDKAMAVSFTIVAPMLNPLTCTLRNAEVNNAMRKLWMKQNTLCYH", "length": 279 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FKQ6-1", "protein_name": "Large ribosomal subunit protein uL5", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVQDQDEKKNPMWELGIHKLCLNICEGESGNRLTRAAEVLKQLTGQSPVFSKARYTVRSFGIRRNEKIAVHCTVRGAKAEEIFERHLRVREYKVQEHISLGTKYDPSIGIYSLDFYVVLGRPGFSFADKKHRTGCIGAKHGISKEDAMSWFQQKYDEIILPGK", "length": 163 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FKY3-1", "protein_name": "Large ribosomal subunit protein eL27", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGKFVKPGKVVLVLAGRYSGRKAVIVKNTDDGTSDQPYSHALVAGIDRYPRKVTAAMGKKKIAKSSKIQSFVKYSVDIPLHKTVVNKDVFRDPALKRKARREAKVKFEERYKTGKNKCFFQKLRF", "length": 125 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FLM5-1", "protein_name": "Small ribosomal subunit protein uS14", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGHQQLYWSHLRKFGQGSRSCCVCSNWHGLIRKYSLDMCHQRFCQHMKDPGFIRLD", "length": 56 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FNC8-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGQRNQTSSLADFILEGLFDDSPAHAFLFSLTMVVFLIAVSGNTLTILLICADPRLHTPMYVLLTNYLSGTKSISFVGCATQYFLFLSLGCAECILLTFMSYDRYVAICHPLRYAVLMNRKVGQMMAVMSWLGASVNSLIHTVILMHFPFCGHRNIHHFYCEFPAVVQLVCGDITVYEIAVYIGDIVLLLLPIALISASYVFILHSVIRMHSAGGKRNAFATCSSHLTVVSLWFGACIFSYMRPRSQRTPLQDKVGSVFYTIITPTLNPLIYTLRNKDIAKALKRVLGREMITQNPKVRLP", "length": 301 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FP10-1", "protein_name": "Ribosomal protein L19", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSVLRLQKRLASSVLRCGKKKVWLDPDETREIANAKSRQQIWKLIKDGLSIQKPGTVHSRARCQKNTLRKGTASAGMPKKSVPERDGNVFKNKRILMEHTHQLKADKARKKLLADQPEARRSKTKEARKRRQERLQAKKEERNRTEVETKFCRLI", "length": 155 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FP36-1", "protein_name": "Small ribosomal subunit protein eS24", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MQDTASIRTRKFRTNQLLPGKQRVIRVLHPGKATVPKTEIWGKLAKMNKRTPDVIFVFGFRTHFGGGKTTGFGMSHDSLDDYTKTNEPKHKRARHGLYEKSKTSRKQRKERKNRMKKVGGTAKANAGAGQKGGV", "length": 134 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FQE1-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTALNHTGVSHTVFYLLGIPGLEDQHLWISIPFFISYVTALLGNSLLIFLILTRRSLHEPMFLFLCMLAGADLVLSTCTVPQALAIFWFRAGEISLDRCITQLFFIHSIFIFESGLLLVMAFDRYVAICYPLRYTTILTHTLIGKIGVTIVLRSYCAIFPIIFLLKRLTFCRSNVLPHTGCEHIGLAKYACNDIRVNIWYGLFVIVSTLFLDVLLIFVSYMLILHAVFHMPSQDARHKALNTCGSHVSVIILFYGPGFFTTLTQRFGRHIPAHIHILLANVCVLVPPMLNPIIYGIKTKAIREQVAHLLFPKQK", "length": 314 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A9J7F7T0-1", "protein_name": "Protein transport protein Sec61 subunit gamma", "gene_name": "LOC100757015", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDYVMQFVEPSGQFVKDSIWLVKRCTKLDRKEFQKVAMSTAMVFAIMGFTGFVKLIHIPVNNIIVGG", "length": 67 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A9J7GY23-1", "protein_name": "Tetratricopeptide repeat protein 16 isoform X2", "gene_name": "Ttc16", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MTDSSTEESVNVQTQKIPKLQVPETRETTLQRIFGTSQVFYSVSGVVKPRLTESTVPFRVREYYHQGHHCLEQEDWEMAVLYFSRALHLNPDQVEFYIFRAEAFIQLCDFSSALQNLRRAYSYEPENSKYLERLAFVLYLQGQCLYELCDFQEALYVFLQASDLQPQNPSFSYRCMACLLALNRHQDCLSLVTREVKQGRATADVYILRARIYNFFQKPKLCYQDLRSALLFNPKHPQAKGLLQVMVDQAKKSLQDASILAVQGKLHRALKRISCAIENNPLDPNLFLFRGTLHRRLQQFDPAVEDFLKAMDMVTDSQDNLVQKTQRQLLLTYNDFAVHCYTQGAYQEGVLLLNKAIRDEQNEKGLYINRGDCFFQLGNLAFAEADYKQALELCPKDEGANLRMGVLQEKMGLCEQTRRQFQKAEDHFSAAIKYNPVNAQYYLHRAKNRQLLQNIVGACQDIATVLLLNPKYPKMAPLMAKLFPGMSVEEVLNSHVAQLAKLQLRRMIESGPKASHPQSIVAKRLIERQKAQALMESWNWEQLFTRNPEEEVAPSESLQGKTLREKIEFKREVVEEKKVKILRKVTSLSDSYVDQTSSGSEFSILSPSTLETEVSTMEYKSTSNTAASSAERLLPQYLVTTKYKESLGLSMAPNVTQVSEDLHKSLTENIPDDGPRHHSSKAEATQRPKPRKTEPSQSLGKQRPSQRPSITEATKGPKPRKNRPALSPRQRLRRAKAVQAQNWKPRTNSNSQKTSSLLSNIAVIISSSNEAQDQSPVPSKADDISSYNDSTATSSTNTDSLRLSIHLSKPKYSKDQSPSHNKEEVSPTSNNYAAP", "length": 835 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A9J7GZF8-1", "protein_name": "Protein EURL homolog isoform X2", "gene_name": "C4H21orf91", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MIIKRKATVIHHKGTMNEEEQFVNIDLNDDNICSVCKLGTDKETLSFCHICFELNLEGVPKSNLLHTRSLRGHKDCFEKYHLIANQDCSRSKLSKSTYEGVKTLLTKKINWIVQYAQNKDMDLDSECSKNTRHHLFNFRHKPDKKLLPQFDSQVPKYSVKGIAGSTGGLSSYTQRILEQRENTDFGLAILQDSDALWPHKHNQAQKKEETSSGPENVQTQNPRYSREELNSMTLDEVEQLNTKLQQQIQEVFEELTHQVQEKDSLASELHVRHVAIEQLLKNYSKLPCLQVGRAGPRSHLPINN", "length": 304 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A9J7JMJ4-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100771730", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDFVNISLVTEFFLVGLTDQPELQMPLFFLFLAVYLITALGNLCLIILTVLNSNLHTPMYFFLFNLSFIDICYCSVFTPQMLMNFILRENIISYMECMAQVFFFCFFVVSECYVLTSMAYDRYMAIYNPLLYNVVMSPNLCLNLMFGSYFIGFSNAVAHTVCMLRLTFCDTNIINHYFCDIPPLLQLSCTSTYVNKLVIFVFASINIIVPTSTILVSYGFILSSIFHISSSEGRSKAFSTCSSHIIAVSLFFGSGALVYFKPSSAVYMNEGKISSVFYTNVVPMLNPLIYSLRNKDIKVALMKSLNSRNL", "length": 310 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0AA74KSW7-1", "protein_name": "Predicted gene 3002", "gene_name": "Gm3002", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLNSSKLGVWAAGVPPSSPTLLFRRWVMKVESLISQPMTSGKNELQDHLIFISEKALHKRLFQKENGDEGVTRPTEKEEGILSHEKGRRKWLWRRHRSARNTSTQNSKMTKKRSKINELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLHENVRILLNENRRLLVEQAGHKCPVGKKRGSLRRPARTSVSQVPRNTSPAESRTWHRPGHDLPQREVLEEEH", "length": 280 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0AAA9RU54-1", "protein_name": "Small integral membrane protein 17", "gene_name": "SMIM17", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MQSLRPEQVRGLLEPERAKTLLPRENKAWEKRAAFAKDWVAVEVGASGCGSDEKDLPSPKTLVPQEWSSVEEDDESEDSQPHWAAALPTSPSCPSQDTGTGSGADLCLQCSSPRTPPWLPWAFSHTIESALPTPPRAWLWSLL", "length": 143 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0AAA9RY85-1", "protein_name": "Core Histone H2A/H2B/H3 domain-containing protein", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNMPEPAKSAPAPKKGSKKAVTKAQKKDSKKRKRSRKESYSVYVYKVLKQVHPDTGISSKALGIMNSFLNDIFERITGKTSRLVHYNKRSTITSREIQTTVRLLLPGELAKHAESEGTKAVTSIPALSKYNMPSRC", "length": 136 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0ABK0KVZ2-1", "protein_name": "Eukaryotic translation initiation factor 1", "gene_name": "Eif1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "EFGFRSVASAGWGAACPLGLRHVISCGGRAGLEQKARALSSSSTGLFPEGQQRAPPDFSDDICTDKKKNQERGINKWPTTTRNKNYFFVDPFADASKGDDLLPAGTEDYIHIRIQQRNGRKTLTTVQGIADDYDKKKLVKAFKKKFACNGTVIEHPEYGEVIQLQGDQRKNICQFLIEIGLAKDDQLKVHGF", "length": 192 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0ABK0L002-1", "protein_name": "Oocyte specific homeobox 2 like 1", "gene_name": "Obox2l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "ILQSVQNTDMIEGPSFLPKFQMSSYTPMDTSSQLPQEPSWNLAFQMGQSPLVTSRTPMQSSPSVPEQNLNWQESQGSSRESSIQMQPGPVMDPGFPTLRSPSGHPSHQRPSRPSSRSGFHVPIEPMALSDKHGGKQTGPVAPRKCRKERTQYSAKQKSVLQEHFAECQYPDKKLCLELATLFGVTENEIKVWFKNNRAKCKQKNVPEALPETNGGPEAVSWSTDFPGSIAVVGCDQGEPMATAILDVDSTPKLNCSQESSLDGNWTYDGAMCCLPEDVLDGNDPVTAGDSGESAPVEAQSDLAAAGAPVAMAVDTQNPEECEDLPLLDEGVWQWMLEDFHQLEDWFTKNYIESPSSASHPLD", "length": 362 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0ABK0LHI6-1", "protein_name": "CD27 antigen", "gene_name": "Cd27", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAWPPLYWLCMLGTLVGLLATPAPNNCPDRHYWIGAGLCCQMCGPGTFLVKHCDQDRAAAQCDPCIPGTSFSPDYHTRPHCESCRHCNSGFLIRNCTVTANAECTCSKGWQCRDQECTECDPPLNPALTSQPSEAPSPQLPPPTHLPYATEKPSWPPQRQLPDSTVYSRLPSQRPLCSSDCIRIFVTFSSMLLVFVLGGILFFHQRRNHGPNEDSQAVPEELCPYSCPREEEGSVIPIQEDYRKPEPASYP", "length": 251 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0ABK0LYA6-1", "protein_name": "Prostate and testis expressed 2", "gene_name": "Pate2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLSCLTSELQGSACLCLPSTGSYKHILQHLDLGTMCYKCKKYHLGLCYGLMRSCTLKHRQSCAAENFYILTNRGQSMYHYSRLSCMTNCEDINFLSFERRTELICCKHSSYCNLPMGL", "length": 118 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0ABK0M6C3-1", "protein_name": "Prohibitin", "gene_name": "AABR07037878.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MYNKNIKNSISISVCVGGVGGVRARAHAHAHTSPHACTRVIHAFVMLEVGPRDFVHIKKAFRGIDVKKPVIFDCRSQPRNVPVVTGSKDLQNVNITLRILFRPVTSQLPRIYTSIGLDYAERVLPSITSEILKSVVARFNAEELITQRELVSKQVSDDLTERAATFGLILDDVSLTHLTFGKEFTEAVEAKQVAQQEAETARFVVEKAEHQKAAAIISAEGDAKAAELIANSLATAGDGLIELRKLEAAEDIAYQLSSSQNITYLPVGPSSVGPSVRQSMFLRLPQ", "length": 286 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0AC58FXL6-1", "protein_name": "Cytochrome P450 2X10.2 isoform X2", "gene_name": "cyp2x10.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSDLRGIYSYMLSTVNSLVRDSSLTNFKKEFCVHAYLLSVCIQYQSSVWSSSRSVTMLTALVLLCLGAFLLYLQLRIRRPKNFPPGPAPVPIFGNLLQLNRISPLKDFDKFAQHYGSIYGIYIGSQPAVVLTGQKMIKEALITQAAEFSGRSNNMMFSHVTGGKGVIMADYGESWREHRRFALTTLRNFGLGKKSMEQRILEEVKHICLLLEESAGKSIDPQHLYHQAASNIIASVIFGSRFNYKDAYFQTLITSVEDLTKITIGPWAMLYEIAPVLRIFPLPFQKAFQYFEQITKHVLKVVEEHKTSRVAGEPRDLIDCYLEEMENKSDHRTSFDESQMVTLLFDLFIAGTETTSNTLRTLTLYLMTYTHIQEQCQREIDEVLGARDHVTYEDRNAMHFVQAVIHEGQRVADIAPLSMFHSAKTDTQLRGYSIPKGTIIIPYLSSSLREEGQWKFPHEFNPQNFLNEKGEFVKNDAFMPFSAGPRVCLGENLARMELFLILVTVLRRFRLVWPKDAGEPDFTYIYGGTQSVKPYRVIVEPRMHGEACKFVD", "length": 552 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AC58J797-1", "protein_name": "Uncharacterized protein isoform X1", "gene_name": "si:dkey-233e3.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MANAKQLLKNSLDELVEAELKEFQWYLINDHRDISKAEMEKADRLKTVDKMVSCFGPKGAVKTTVDILRKINQNELAEELENKHKQGNCMSARAEGAVLETCKSPPFDYTNTSRELKKKLKEDYEKILVGNSQTGHKKYLEDIYTDLYVVENETGGRERQHEVIQMESKHNQQDRPLKCNDMFKVQPDTGRKHRRILTLGIAGVGKTVSVNKFILDWAEGKDNQEIVFIFPLPFRRLNLIKEEKYSLIGLLNKYFFSISGGLSSLPEKQGKVMFIFDGLDEYRFKLNFKKDDGFTDVNKEMTVSEIITNLLKRHLVPSSLMWITSRPAASSLIPRDLIDQVTEVRGFIDEQKEHYFIKNSSPEVARNIIGHIKKSRSLYIMCHIPVFCLISLTVLQPLLGQESNEKTPTTLTGMYINFLLSQKQQMKEKYRNDTESEANACSFDEIVLKLGKLAFKQLQKGQLIFYKTDLEKCGLDVRQGSVFSGLCTRMFQEENHYSGEQVYSFVHLSVQEFIAALYVFFTYKNKKANLFLDSWKKELKWKLSEKPLFKLHTAAVKKTLQSKNGHLDLFLRFLMGLSLESNQSDMKELLPWLKLKTGMIKDTTDYIKKKIEEENSAERTINLFHCLNELNDDFVEELQKSLCSGNLTAQDLSSAQWSGLVFVLLMSEETQEKFELQKYRRSDEALMRLIPVVKNTTRALLQCCNLTAQSCESLSSALQSSNCVLRELDLSNNDLQDSGVNLLSNGLKSPKCKLEILRLSGCMVTEEGCGFLSSALTSNPSHLRELDLSYNHPGDSGLKLLSQKLEDPNYTLNKLNLDHGGEKWFTAGLHKYACFLTLAPNTAHIELRLSEENRRVTRVGERQQYPDHPDRFDHHAHVLCRESVCGRCYWEIEMNAGDRVDIAVSYKSIKRKGRGYECVLGQNAQSWALICYVNRVAFRHNMIETRLPVKLMSRRIGVFVDHSAGTLIFHNIYRDSMSLIHSVQTTFTEPLYPGFWVEYGSSVKLC", "length": 1006 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AC58JHM1-1", "protein_name": "Phoenix isoform X1", "gene_name": "pho", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDLRSKGDTSVGEVMEADPRAELIFETPPPDVVSSINACFEEIDSALKIRRDPSVHSPPSDSDSESLFITQSVTKVVHTKRRLRSSKKPDSISDDSGYVRERRLSENQQTECEEESRSLRSSRRKRSKWEMYASARKATFPFLMKSLKTQHLPIRKHQILENSEVGGFFKCIKKIKTGSVKMGKVISSHLFQSPISDSSEEEDQNSEHDVISVDKALFVPGYKRGINFKWLPDFIRERRTLENYLSNGVDKEKKTEQIIEYRQRNQHPQRTSAKALSKSSQVSKKPKKQDTHEVLASCSDHEDLEIAECAENSHEGHKVVIEETQRQTVEEASAHLEHEDDLNCKVVEYRKRKRHPKRTSAKALSKSSQVSKKPKKQDTHEVLASCSDHEDIESVECAENSHEDHNVVIEETQRQTVEEASAHLEHEDDLNCKNQPDVDQPNESNFIGPPQEGDISTQSDTQQTDSDIGSVDLFSPLNSPKRDDQIPNTTSITANVEENDQDSDVTQIESEGQHVSTFTQETQKCFANEEYDSDETHIDTESLSRFKPRTPNKQFTSTKHPEIPQFRVQSPKPPSRQAETVNVQLSPKHLPLSNVPLSEVPISPCESAIVGRQKTMVETETDSPMFKITGPSFLKRKRKRTKDKNAAADFKQHDTNGDVGQMVSCPGDDITGLKAVPIENIEACGVEHEMAIGEQTEELGLKSKELLEESVLSTVNSVSTKSKREKMKKYKVKECEAVENQLVETSKKAKKKKKDKERIATSYPEENNLTNIQSNEGFDSAELRVKEVNQSSQSLNTDQPTCVQTSEEITGETELKKKTTRHETDDPLYESVGLDVTLASQFDVGLRIDEQQEGLVTEEAERDERLQGKAMKVAKGKKKIQDTSFQVDHDIGLDKQRSDSGAKPANLDLDGLESLTIKKKKKKKKKHKLKEKTDPKLDFDFDHNVQFFQTDRLQTTDSVLLDSTHTNKQKKKKLKCQNDTDQSSDLKQLHVVGSKLQTIDLPKTDKHMERTGVSSSDALLEHMDDRTLGMRENNTIQTDQIEHLQTSEEVTRCSSPRLSSDKKREKTSVHPNLDASSVFQFDGFKANEDQAITQNTTKEKQISSEQLENNLVGPPSQVENIANVNSSVLLDHTHMNTLREGQLKEQTYKELALAFGLKQLCIVVNKLKTTDLPKTNKNMEGTGVGSSDELLKHTDDRTLETRENNTIQTNQIEHLQTSEKVERHSSPRVTRLSFAKKWMKTSVDSNLDASSGSQFDGLNSMAKEDWTFSQNMDLPLKRTKNKQKDKERTGVSSDALLKRMDDRPPEMRKKNTIQTNQIEYLQTSEKVTRRSSPRLTRLSLAKKMEKTSVDPNLDASSGSQFDGLKEASKEDRTAPRNSIEEKQSDAISSEGLENNPAHLVSTNKSDNTSPSSQVDNIVGLQSDANSVLLDHTHTDKQKKKKIKHKLIEQTEKELTSEVEDNVQPFQFIELRAMDLPSKRITNKKLKDRKRTGVSSSDAVLKHIDDGPSDMRENNSIQTDKIEHLQTSEEMTRCPSPRLSSDKKRKKKYVDTNLDASSGFQFNWSNGMAKEYSKNSTNISSLDNMHTSKQKKKKKQKLKEQKNVESVGDNVYSLEPDQFSGLQITEIKTKKKDKKRTKQANVEENDLKGILSNKAFKASQTYQLEHIQTSEEIKGRSPNAASKSAKKKKKKKNETKNPQYESVNLDLSLAKEDRTTTQNHTEETQGDGNAVEHLEMNPAGLIKVSKKKKKRENAGIVQLDNIIGLQSGSSTDVKSSVLSDSTDTNKHKKKKRKTLKEQENVEAEGDDVQSVEPDPFSGLQITEMTTKKKRKHKRCEEQRCLRGVSSHEAFKAPPTNLLQHIQTSEEISQCQSPNVAALENGGSPYQLENITEMQPGNSIDINSSEILYSTCTHKQKWKKLKQQENVEADANDVHSAELNLFSELKISEPTTKKKKHKKCVEKCALKDISSNEGIKAPQTSQLEHVQTSKEITQCQSPNAATLKSEKKKKQKRDETEVPQYLDASSVSQFDDVTRLKKQAKVDRTTTQNSSEETQNDDISSKQLEMNPAHLIKVSKRKKKREKAGSPYKVDKIVGLQSGNFTDVNFSQLSDSKRTDKQKKKKKIKLKEQENAEADVDDVHSVELDQFSGLQITKPTTKKKRKHKRCVEESGLRDISSNEAYKAPQTNQLEHIQTSEEITPFQAPNVAALKSAKKKKKKRDKTVEPQCLDASSVSQFDDVKTRAKEDQTLTPNSSKETQGDDSAVECLETNPAGLMKVSKKKKKRENAASPYKVDNIVGLESGNSADVSSSVPSDSTDTNKHKKKKRKKLKKQEIVEADLQTSEEIIQCQSPNVATLKSVKKKKDETKEHQRLDVSSVSQFDDVSRLKKRAKEDRTTIQNSSEETQSADISSEQLEINPAHLIKVSKRKKKRENGRSPSQVGNIVGLQSGNFTDISSSVLSDSTRTDKQKSKQKKKLKEQENVEADANDFHSAEPDQFSGLQITEMTTKKKKKHKRCVEESGLRDISSNYAFKAPQTNQLEHVQTSEEITQCQSPNVAALKSEKKKKNKRDKTDKPQYLDESSVSQFDDVKKRAKADRTTTHNSSEETQKDNISSECLELNPAHLMKISKRKRENKSLGLLSENTADLNSSSLLDGTDTDKHKKKKRKKLEGQENVEADVDDVHSAEPDQFSELQIPEMTTKKKKKHKRCVEESGLKDISSNEALKALQTNQLEHIETSEEMTIKTVKKEKKKRDATEEPHYKSVDLDVSPTESTTEAKLNPTKHKKKRKQSFSGSHDAHEAPERKRKKDRN", "length": 2809 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0MGZ5-1", "protein_name": "Heparan-sulfate 6-O-sulfotransferase 1-B", "gene_name": "hs6st1b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNDTERNMVERTSKFLLIVVGSVFFMLILYQYVAPGVINFGSPHGYLLGEEDMTIFPTPDPHYVKKYYFPIKDLERKIDFEIKGEDVIVFLHIQKTGGTTFGRHLVQNVRLELPCDCRPGQKKCTCYRPNRKETWLFSRFSTGWSCGLHADWTELTNCVPGVLNKRESKSKKMRKFYYITLLRDPVSRYLSEWRHVQRGATWKTSLHMCDGRTPTPEELPPCYEGTDWSGCTLQQFMDCPYNLANNRQVRMLADLSLVGCYNLSTVPEKRRSQLLLESAKKNLRDMAFYGLTEFQRKTQYLFERTFHLKFIRPFMQYNSTRAAGVDLDNDTIQRIEELNDLDMKLYDYAKDLFQQRYQYKHMLDRREQRLLRGHASFHSPFREDGAGGEGTARLPTEDYMNHIINGW", "length": 407 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A1EC97-1", "protein_name": "Dual specificity phosphatase 14", "gene_name": "Dusp14", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSRGHSTLPRTLMAPRMISEGDIGGIAQITSSLFLGRASVASNRHLLQARGITCVVNATIEIPNFNWPQFEYVKVPLADIPHAPIRLYFDTVADKIHSVSKKHGATLVHCAAGVSRSATLCIAYLMKFHNLCLLEAYNWVKARRPVIRPNLGFWRQLIDYESQLFGKSSVKMVQTPYGIIPDVYEKESRHLMPYWGI", "length": 198 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A1XQX2-1", "protein_name": "Neurexin-1b", "gene_name": "nrxn1b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MMILHLGAHLLFIGLIVCKANAGSSLRFTGSDEQWVAFPMWNACCESEMSFSVKTTHLNGLLVYFDDEGFCDFLELHVHVGKLRLCFSIFCAESTCVLSDVAINDNRWHSVSIMRNFRNTTLIVDDEVKWEEVKSKRRDMTVFSHLFLGGIPSELRSVSLQLTSKTVKDHTSFTGWIMDVKVNDSEPAIISSAGVHEDLCGSENTCLNGGVCSVVEDKPTCDCSQTGYQGKDCSEGLAHLMMLDRGMEEYVATFRGSEYFCYDLSLNPIQSSSDEITLSFRTLQRNGLMLHTGKIADYVNLALKNGAVSLVINLGSGAFEALVEPVNGKFNDNEWHDVKVLRNLRQHSGVGYAMVTISVDGILTTTGYTQEEYTMLGSDDFLYVGGSPSTADLPGSPVSNNFMGCLREVVYKNNDAELELSRLAYQGDPKLQIHGVVAFKCESVATLDAITFETPESFLTLPKWNAKKSGSISFDFRTTEPNGLLLFSCGRAKQHNKEAKSPVTLKVDFFAIEMLDGLLYLLLDMGSGTTKTLALNKKVNDGEWYHVDFQRDGKSGTISINSVRTPYLCPGDSELLDLDDPLYLGGVPESSSGTVFPTGAWSALLNYGYVGCVRDLFIDGRSVDVRRAAELQRAAGVKPSCGKEPSGKCVSEPCLNRGVCREGWSRYICDCTGTGFLGHSCERDATILSFDGSKFLKVQFSAAMHTEAEDVSLRFRSLRAYGVLMASTSTHTTDTLRLELEAGRVRLTVNLDCNRINCTTSKGPESLFAGQNLNDDEWHTVRVIRRGKSLKLSVDDLPTVDGEIPGDHTQLEFHNIETGIITGKRQLPTMPSNFIGHLQSLMFNGKPYIDLCKNGDIDYCQTNAPIGFKSIIADPVTFKSCSSYVTLPSLQAYYYMYLFFQFKTTSADGLILYNSGDGNDFIAVELVKGYLHYISDLGNGAHLIKGNSIKPLNDNHWHNVMISRDPNNLHTVRIDTKTTSQTTLGAKNLDLKGDLFVGGVPEQMYKDLPKLVHAKEGFQGCLASVDLNGRLPDLMTEALVCIGQIERGCEGPSSSCEEDSCANQGVCLQQWENFTCDCSMTTYAGPLCADPGSTYVFGRQGGVITYSWPPHDRPSTRVDRLALGFITLMEDATLVRVDSSAGLGDYLKLHIVKGNVVAVFNVGTYDINIEENGKLVNDGNYHIVRLTRSGGNATLQVDDLPVIERFPPGHIDSHRLGTGRLPYRRLVEESLPKNGRQLTIFNSQMTIRIGGWQKQQVSGFQGQMSGFYYNGLKVFSMAADGDPNVRMEGSVRLVGELQSSSTPHGGATVYQSSVTEISSTTSNTITITYSTPADEQQTTDELLVASAECPSDDEDIDPCEPSSGTLCCFVPPAGPTGPAISSFPGPAEVFRESNGTTGMVVGIVAGAALCILILLYAMYKYRNRDEGSYHVDESRNYICNSNGAALKEKNTADDDSGSKSKKNKNKEYYV", "length": 1470 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A2A7I1-1", "protein_name": "Zinc finger protein 978", "gene_name": "Zfp978", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFAPHQESGRRTTKRMSASLENTAQCLLTFKDVFLDFSSEEWECLNFAQRTLYMDVMLENYNNLLFVENHCICGNYEKEKVVEQDTQHIFNEHGHIQEKSFKCNESSNIIHESSESTPHKTNHRDATLQSSNLKRHKTGTTKQVCTYKDCVNCLKGSSIISLNQGTHVEKKEHNRNKNLDEVLVSKHKPIVRQNNSEMNTYTCGEFDKCFTQSDNLQSQQRIYPGKKSYKYSESDKCFTQPSHLSIHHTIHSGEKPYKCSECDKCFTDKCTLRKHQRIHTGEKPYKCNECDKCFTDKGSLRVHQRIHTGEKPYKCSECDKCFTQTSHLSIHRRIH", "length": 335 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2A8N2-1", "protein_name": "PRAME like 25", "gene_name": "Pramel25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVICGHCPDQDESLEEVTEECYSPPTLQNLAIQSLLRDEALAISALTDLPQSLFPVIFEEAFTDGHIGILKAMIPEWPFPYLSLGKQINNCNLETLKAILEGLDILLAQKVQTSRCKLRVINWRDHDLNLWAGSHEGEGLSEFTTEKQPIENSPGCEVKKELKVMTEVLRMKGRLDESTTYLLQWAQQRTDSINLFCRKLVIEGLTKASVIEIFKTVHADCIQELILRRICIEELAFLNPYLKLMKRLFTLTLDHIIGTFSFGDSEKLDEEIIFSLISQLPTLHCLQKLYVNDVPFIKGNLKEYLRCLKKPLETLCISNCDLSQSDLDYLPYCLNICELKHLHLSDICLRDLLLEPLGFLLERVGDTLKILELESCCIVDFQFSALLPALSQCSHLREVTFYDNNFSLPFLKQLLHHTALLSQLISECYPAPLECYDDSGVILTHRLESFCPELLDILKAKRQLQSVSFETTQCSKCGGCYIYDQETQCCHFVELLLA", "length": 498 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2A9Q9-1", "protein_name": "MAGE family member B5B", "gene_name": "Mageb5b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPRGQKNKHHRNRLKNKKHNQEKVHPQKDESQEKGHHKRDDFQDHKEARDNAAVEEKSSCSSPSVPGETLEKPPASKTSSDAGWLSCVSSPATVCGDELEFDDGTYFHCGGNSLYSEYRTCQENPCKHCLDMYVNLVEQYVLYKFKMKKLIDRNKLIDLIEPKYRYNFSDIFKRAFENIEIVFAASVIEIDSTNHVYDLVSKLKLPNKGRVCPGRGLPKTGLLMTILAMIFMNGTSASEEDIWKFLNYMQVYPGRKHFIYREPRKLITQDFVKLKYLEYKQISLSDPPCYRFQWGPKAYTETTKMKVLEFMAKGSGVEPSTFSVQYTEALREENQKTKIRKWYPILAQKHCPGHSHQHVQKVMKPQ", "length": 366 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2ADW8-1", "protein_name": "Predicted gene 15128", "gene_name": "Gm15128", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MANREDEIRQLRYLEAANSEEEYNEENDIQSESSRGQAFFPGHPRGRGHRRDSRGRNGHFFRQRFSANHPLLHLTRQVNLESLTRRNGNQSEERQLQQERIQLFFRSLHGLSQSHDHHIGRSHGHDSRRSRNRFRRAPVQSERSHVYSGRTNNYTDRPQHDLSNRPHNQLSVRPHPDLSGRPLHDYSGRPHQNHAVRLQHGHSDRYHLTHTERVLPNNSGIAHPGHTERDNQVQRGRAHDNQSGLAHHNHDGRSHHDHSGRAYHGHARRAHNNQSWRSDNNQSWRDLNQSWRGQNNQSQRGHDNQSQRGHDNQSRRGHDNQSQRGHDNQSQRGHNDQSWRAHNIRSRRDRYHTSLRSSSIQSWMLHERERYHGPRGRNGPRDASPPGSEPEIDRSSAIRERTDYLWVQEHRRNETVELNVGLEDGYSSAEESDESFDRLTCRSMLDTLY", "length": 449 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2AGW6-1", "protein_name": "PRAME like 22", "gene_name": "Pramel22", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MHRLLREEALAISSLKDLPNMLFPVLFEEAFIFGYTKILKAMIPEWPFPYLSIAVLIDNCNLESLKAVLEGLDILLAQKVHSSRCKLKEISWRDTNHGLDGIRPGSHEVEGLSEFMEQKHPNCVEKKELKVTTELSVMNGRLNESDTYLLEWTQQRKDSIHLFCRKLVIQSLTKATVIEIFKIVNADCIPELELCSLCLEDLAFLNPYLRQMDNLLELTLDHITDSLSIGDSEMLEERMITLVSQLPTFPCLQKLCINDVYFIYGNLKEFLGCLKKPLVSFCISNCELSQSDLDYLPYCLNIFELKCLYIINIHLQYLCLEPLGFLLESVRHTLGCLALKSCNMGEPHFKSLLPALSQCFHLTDVNFQENELSLLSLKQLLQHTSKLTQLSYEMYPAPHECYDDRGVILSHRIEQFCPEVLDMLRAKRQPKDINFVTTQCSKCGIYYVYDLETQRCRFLK", "length": 460 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2AGW7-1", "protein_name": "PRAME like 23", "gene_name": "Pramel23", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNVNSPPTLMKLASQRLLREEALAISALKDLPNMLFPVMFEEAFINGHTKILKAMIPLWPFPYFSLGMMIKNLTLDTLKAVLQEIDILISKVVHSSRCKLKEIKWKNTDYGLQGIWPGSHEFDGLSEFMEQKQPDCGVKKELKVITHLKLMEGSLDECATYLLQWAQQRKDSIHLCCRKLKIQGSINATVIEIFKIVHADCIQELELCCLCLEDLDFLNPYLKQINNLIRLKLDEIKGTVSMGESRNIDEEKVITLISQLPTLQHLEKLCINDVSFIEGNLKECLRCLKKTLEILCITNCYLLQSDLDYLPYCLNILELKCLDFSNIPLSHLFLEHLRFLFERVRHTLECPILKSCEMGESQFNSLLPAISQCCQLTEVNFYDNELSLIFLKKFLHHTAKLSQLTYELYPAPLECYDNRDIILSHRLENFCPELLNILRAKKTAQGGHLCYNPML", "length": 455 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2AHC7-1", "protein_name": "SSX member B14", "gene_name": "Ssxb14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "METVISCEKIPMEVLHKPKNICKAFQDISTYFSGEEWGKLTEWQKSAYMYMKRNYTRMTGVTVNQPVFMSGKEQAKQSLVKGIEVHDSEDECFEESFGVTPRKRMKLTSVTISIHNVEGSLASGENDSNLAETDGIQVNVWSHRLRERKYRVIYSEISDPEEEEDDDY", "length": 168 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2AK42-1", "protein_name": "Pre-mRNA-splicing factor CWC22 homolog", "gene_name": "Cwc22rt5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKSSVAHMKQSSGHNRRETHSSYCRSSSPEDRYTEQERFPRDRDYSDYSRSDYERSRRGYSYDDSMESRSRDREKRRERERDADHRKRPWKSPSPDRSPARGIRQSSPQEEPTWKKKKDELDPLLTRTGGAYIPPAKLRMMQEQITDKSSLAYQRMSWEALKKSINGLINKVNISNISIIIQELLQENIVRGRGLLSRSVLQAQSASPIFTHVYAALVAIINSKFPQIGELILKRLILNFRKGYRRNDKQLCLTASKFVAHLINQNVAHEVLCLEMLTLLLERPTDDSVEVAIGFLKECGLKLAQVSPRGINAIFERLRNILHESEIDKRVQYMIEVMFAVRKDGFKDHPVILEGLDLVEEDDQFTHMLPLEDDYNPEDVLNVFKMDPNFMENEEKYKAIKKEILDEGDSDSNTDQGAGSSEDEEEEEEEEEEEEEEGEDEEGGQKVTIHDKTEINLVSFRRTIYLAIQSSLDFEECAHKLLKMEFAESQTKELCNMILDCCAQQRTYENFFGLLAGRFCMLEKEYMESFESIFKEQYDTIHRLETNKLRNVAKVFAHLLYTDSLPWSVLECIKLSEETTTSSSRIFVKIFFQELCEYMGLPKLNARLKDETLQPFFEGLLPRDNPRNTRFAINFFTSIGLGGLTDELREHLKNTPKVIVAQKPEAEQKKTALTSSSSESSSASDSSDSDSDSSESSSESSSEASDSSSSSSTQSSTSAKGTRKKRQGKARGEEVDKLARGHQALERRQGGREDQRHQEGRTERARSERHRAQNSRDADWRDSLAKHIDDRSHENSHSRVGNGREQGSHREPEDRHGEPKKKQREKRFFL", "length": 830 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2ANE0-1", "protein_name": "Reproductive homeobox 2F", "gene_name": "Rhox2f", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MERQSINYLLDVGPEEDEENANGVKTLMVLLAGDGRNEGESGRGLPGSGASAAEGYRAGEISAGGPAAQVADLMDDSNQEDLGATACDQEKEKQPEEPVPDSMGDLENVKRVSGPWSTVNPVRVLVPKFRHLWRHSFNVLQLQELESIFQCNHYISTKEANRLARSMGVSEATVQEWFLKRREKYRSYKRL", "length": 191 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2ANE1-1", "protein_name": "Reproductive homeobox 3F", "gene_name": "Rhox3f", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSMKPERSMSNWIHSNVEPAGRNLFQVNGHRSALLPELPQDYHRASRSVNGCETKMDNTQGTKVLPAEEARNEEDGGQVESALGATAARGRGKEALNGESPAAAGTAGLVEEDRNKEDGGTKGGEKNEQEVREQIPEHVEGESDQAEALRQVPRRRLHHRFTQWQLDELERIFRMNYFLSLEARKQLARWMGVNEAIVKRWFQKRREKYRWYKRL", "length": 215 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2ASJ1-1", "protein_name": "PRAME like 14", "gene_name": "Pramel14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDLEAPPTLLQLAAQCTVRKEVLTISVLQNLPMKLFPPLFKEADILRKAKMIKLLVEYWPYPSLLVGLLIDKTNLETFQAILEGVGTWLKRKYRPRMGKLQVVDLRNGHHDFWDMLAGREGGDQLVETMPEKQEVEGHSRRQRLRVFSDLSFKSSRHEDKQQTHLLQWAKDREGFLHLCCEKLEIGALGVSKVKKVLKLLQPEFIKELELNTVGNLSKLTKLVPCISKMRNLQKLMLVRIFGRHTYTPLEERNVTKILSLFPKLSYLQHLTIDDVYFLRDHMNELFRYLEAPLLSLTITLCQISQSDLESFSQHWNYGQLKHLCLKGVSLSTLNVTPLKFFLESVADTLQTLELEDCRMKDSHLRILLPALTKCTRLTSINFYDNNISRDVLQDLLHRTANMSQLTMELYPAPVEVYNEWSYVQVERFSQLCAELMNTLITVRRPKSVCFGTYSCYDCDTHCIYGNQTTFCECLE", "length": 475 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2ATW2-1", "protein_name": "Olfactory receptor", "gene_name": "Or4x15", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADIHNVTEFFFLGLSSNQEVQRVCFVIFLFLYMAIVLGNLLMVVIVAVSRNLGSPMYFFLSSLSFVEICYSSTTAPKLIVDLLAEKKSISVWGCMAQLFFMHFFGGIEMFLLMMMAYDRYVAICKPLHYTSIMNRQVCTVLVGMAWMGGFVHSLAQVLLIFRLPFCGPNIIDHYFCDVLPVLKLVCSDTFLIGLLIVVNGGTLTVISFVVLLSSYAVILFHLRTQSAEGRRKALSTCGSHVTVVVIFFAPCVFIYLRPTATLPIDKMVTVFYTVITPLLNPIIYSLRNAEVKKVIKILCTRATKVDKK", "length": 309 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2AWL9-1", "protein_name": "Reproductive homeobox 2C", "gene_name": "Rhox2c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MERQSVNYKLDVGPEEDEENANGIKTLMVLLAGEGRNEGESGRGLPGSGASAAEGYRAGELSAGGLAAPVADLMDNSNQEDLGATGCDQEKEKQPEEPVPDSMGDLENVKRVSGPWSTVNPVRVLVPKFRHGWQQSFNVLQLQELESIFQCNHYISTKEANRLARSMGVSEATVQEWFLKRREKYRSYKRL", "length": 191 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2AWM0-1", "protein_name": "Reproductive homeobox 3C", "gene_name": "Rhox3c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSMKPERSISNWIHSNVERAGRNLFQVNGHRSALLPELPQDYHRASRSVYGCETKMDSTQGTKVLPAEEARNEEDGGQVESALGATAARGRGKEALNGESPAAAGTAGLVEEDRNKEDGGTKGGEKNEQEVREQIPEHVEGESDQAEAPRQVPRRRLHHRFTQWQLDELERIFRMNYFLSLEARKQLARWMGVNEAIVKRWFQKRREQYRWYKRL", "length": 215 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BED8-1", "protein_name": "Predicted gene, 58953", "gene_name": "Samt1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDQLIVDTRSVIYRFINEKDCIYKLSGLLSSLAAFMLEVLIASILSWRLWEFDSNVVQFVSFGLFEAYYPQQFNISGTLTKMLVYTPIDSTWNISTEFMYAQNLVVWAILMKPVVLVFCVMAIKISCTKNPLVEMQIYCYKISALILSVSSMFTFVSVIWNHMVDFYGHTTLDFPSDFPVKKEALTSKHLTVVLPVGLLIATMSLFGVIMFLSEISDLKLKRPVKANDASKMGLLDA", "length": 237 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BEE3-1", "protein_name": "Spermatogenesis associated multipass transmembrane protein 1d", "gene_name": "Samt1d", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDQLIVDTRSVIYRFINEKDCIYKLSGLLSSLAAFMLEVLIASILSWRLWEFDSNVVQLVSFGLFEAYYPQQFNISGTLTKMLVYTPIDSTWNISTEFMYAQNLVVWAILMKPVVLVFCVMAIKISCTKNPLVEMQIYCYKISALILSVSSMFTFVSVIWNHMVDFYGHTTLDFPSDFPVKKEALTSKHLTVVLPVGLLIATMSLFGVIMFLSEISDLKLKRPVKANDASKMGLLDA", "length": 237 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BEI6-1", "protein_name": "Myb/SANT DNA binding domain containing 5 family member 10", "gene_name": "Msantd5f7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQREDNRVQSVRSDKEANRRRRLRQEGQSSSGPCDSPWTEDEIWILLQEWAMVEYELGDPGNKMHAKAKSLSRRLSNRGLRKSKNSCLDVMVKMKDLHTRLCNERPRAYRLYSTYEWILYEILGHPRSQGGYVPGLWFDGHSKPPASYAPSLCIGGAISPGPSFSPWTDPEIKIFLQEWQVVEREIGHPGQKIKQKSSLVCQRLYHRGLFKDIQSCLDLMWTLKDLHSTLSRERSRTVPLFSPYRDYLERIFDPKCQRGHVPGALYNWSGYHRPSSSPQTPMVMPSPVYQPWDYGMSASSGQLHGNPSLIMSSQDSLVPRWDAWNATYPLPVQHVLLASLSGDNNFQLAWSPRDESSSPQ", "length": 360 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BEI8-1", "protein_name": "Myb/SANT DNA binding domain containing 5 family member 8", "gene_name": "Msantd5f8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQREDNRVQSVRSDKEANRRRRLRQEGQSSSGPCDSPWTEDEIWILLQEWAMVEYELGDPGNKMHAKAKSLSRRLSNRGLRKSKNSCLDVMVKMKDLHTRLCNERPRAYRLYSTYEWILYEILGHPRSQGGYVPGLWFDGHSKPPASYAPSLCIGGAISPGPSFSPWTDPEIKIFLQEWQVVEREIGHPGQKIKQKSSLVCQRLYHRGLFKDIQSCLDLMWTLKDLHSTLSRERSRTVPLFSPYRDYLERIFDPKCQRGHVPGALYNWSGYHRPSSSPQTPMVMPSPVYQPWDYGMSASSGQLHGNPSLIMSSQDSLVPRWDAWNATYPLPVQHVLLASLSGDNNFQLVWSPRDESSSPQ", "length": 360 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BFR3-1", "protein_name": "Histone H2A", "gene_name": "H2al1j", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAKKMQRRRRQKRTHSQRGEFPLSLVDRFLPEGNHSGRLSSSAPVILDSVLEYLSSNILELAGEVAYTTGRKRIAPEDVGLVVQNNEQLCQLFKPGATSVFDPPEPDDN", "length": 109 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BFZ7-1", "protein_name": "BTB domain containing 35, family member 9", "gene_name": "Btbd35f11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BH64-1", "protein_name": "Secretoglobin, family 1B, member 30", "gene_name": "Scgb1b30", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKLTGALLLLGAALLLTSEGDCGLCPVLQKKVHKFFDGTTEEYVEYLKQYNNDPLVLENAANIKKCSDRMLAEEDKTQATNFINKVTGSRSC", "length": 92 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BHG6-1", "protein_name": "BTB domain containing 35, family member 7", "gene_name": "Btbd35f7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLSCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYRDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSFGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BI40-1", "protein_name": "X-linked lymphocyte-regulated 4A", "gene_name": "Xlr4a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASKIKGRPPKQPKVTPALPSDDSQQLHENNPGNNLALETCGESSSSHGTGGPKPGPSKKTLNERKRKYGVSVNKTVQNIEWNVDHFLKVQHERRQELYKDYSHQFLTLVMMWNIDVDQIKKQAGKLSDILDEQQKLFQQFQSIHMQKIEEFKELCDRHLKNLQAIKCCRRKAIIEEARKLMDYLEKTVTEETVHVNKQEAKDGVQSSLLSLLIS", "length": 215 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BI45-1", "protein_name": "X-linked lymphocyte-regulated 5A", "gene_name": "Xlr5a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSNKEQKAMKKSGKHQRVHKTLPSDDFKNSDEVNPADKPAVGTSGMGSHSSGSDMQEAREPVQKKMQDFKGDDGTGLLMEKKKQFEEDVNASFRSLNENLQSILKAQQNSRQELKSLYCERFGSVYHNWLVEMDRTRDQEEYFSFITQQQMKILQTAIEDHETKLKNAKDMCDTFLKKANDLSKRQKTFIGGQHTIVEKEISKVQNRVIMETQDQDISMVETYLQSLIHESSEETI", "length": 236 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BI50-1", "protein_name": "X-linked lymphocyte-regulated 5B", "gene_name": "Xlr5b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSNKEQKAMKKSGKHQRVHKTLPSDDFKNSDEVNPADKPAVGTSGMGSHSSGSDMQEAREPVQKKMQDFKGDDGTGLLMEKRKQFEEDVNASFRSLNENLQSILKAQQNSRQELKSLYCERFGSVYHNWLVEMDRTRDQEEYFSFITQQQMKILQTAIEDHETKLKNAKDMCDTFLKKANDLSKRQKTFIGGQQTIVEKEISKVQNRVIMETQDQDIAMVETYLQSLIHESSEETI", "length": 236 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BI74-1", "protein_name": "SSX member B6", "gene_name": "Ssxb6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "METVSSCEKIPMEVLYEPKNICKAFQDISTYFSDEEWVKLTQWQKSAYVYMKRNYIRMTDLGVTVNQPVFMRGKEQAKQSLVEGIEIHDSDDECFEGSFGVTPIKRMKLTSVTISIHNVEGSHDSGENDSNLAETGGIQVNVWSHRLRERKYRVIYSEISDPEEEEDDDY", "length": 170 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BIM8-1", "protein_name": "Major urinary protein 18", "gene_name": "Mup18", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMLLLLLCLGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILASDKREKIEDNGNFRLFLEQIHVLENSLVLKFHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAQLCEEHGILRENIIDLSNANRCLQARE", "length": 181 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2CEK7-1", "protein_name": "Major urinary protein 14", "gene_name": "Mup14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMLLLLCLGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILASDKREKIEDNGNFRLFLEQIRVLENSLVLKFHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAQLCEEHGILRENIIDLSNANRCLQARE", "length": 180 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2CG71-1", "protein_name": "BTB domain containing 35, family member 19", "gene_name": "Btbd35f20", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLQPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSVYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKMRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTLKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2CG92-1", "protein_name": "BTB domain containing 35, family member 10", "gene_name": "Btbd35f10", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIHALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2CGC2-1", "protein_name": "BTB domain containing 35, family member 3", "gene_name": "Btbd35f4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQRMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 496 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A3KG49-1", "protein_name": "PWWP domain containing 4C", "gene_name": "Pwwp4c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDSSEYVLCGWKSQLCPARVLSRPRTPAHSKRRGVPFLEVQILPVGEKRRVRSSKVRPLAKSEIISINSLAGKESRGRGSPGQTRASRRALKVALDGLGEGSSFFQGGRAGSRRTSTLAPKVPKEQASSSSSSLGQRLRLRLRQLLPLSLCQRLHLHLRLRLHLHMHLCLQGRNQKGQGLSQRSPGKRVRPDPGPVMMGSQNVPAVPVGEAQAHTAAGLPRSEVEGDVLRGTRVWPSYSKKTPLGKAGGNPGKRKPGTGKRKLRSLSAPASRKGTRSKTEQQAASGPPRHISISPKALKQRVRCAGLEIRAAGAQRKTALAENKDHPGLGTPKPDSKRASAACMPPVLRLRRSLRIASRKKKTHVLCALCGLPEWEPQVHSKVTNTRFKRRGARVQKDAKATNVVSAQEPSTIEQGTLVWFKFQDLPFWPAVVKSVSKIDKMARVLLIEGNMQFERRGIRVPLRKLKHLDCGEKVSLVRRASRLYAQGINWCFSVIDHYREGLSRGSLLGSFMDYYTTQASYPLRRAVQEGDLHIDFPKVSYAELEDWEEETALGGKGPYKKLLPDRMRAAWDRANQKLVDFIVKRKGADQHLLDIVKGRKPSRWLDDLWKSKREVFCIETYLEDDDQLHLVARHLQEVAKEADEALLSLARGDKVRFTMEVLFPEAIIYSIAALDELSYKEAEEKYLRGPPVHYREKELFDKTILKAARKRSAARIRAARDPPVPTP", "length": 728 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A5WVZ0-1", "protein_name": "2.7.1.138", "gene_name": "cerk", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEKQSTLLCSELSVQRRLYEVTLNCAILAWKDVQNAKKHTGRAIYGAVKAGSHCVPVCEIIAVQEKEDDSPCKDTGKWQKVPQSPTDSCQHAFTVYYVERTRQHCWRCSNVTFQYSEHSLCLLWIQTIKEQLALLSAQSTEELAGVHQPLRRKTTRQADLRPQSGPHLFPGFHFHRRDWPHSFSAHPSELRFYIIADGKEPVMKCTGDCFSPRVQLHHLMQLIDGLHQASRKMQFNCQMNIMMFLPPLYHQPGNNGFSLFVSIVTEHANHARDHLKAEADLKKYDGVVCVGGDGMFSEIMHGLVSRTQQDAGVDENSTEETLIPCGLRIGIIPAGSTDCICYATVGSNDPVTSALHMVVGDSQPMDVCSVHSDDRFLRYSVSLLGYGFYGDVLKDSERKRWMGPARYNISGVKTFLSHRYYEGTVSFLPAEENLGTPRDKVQCRSGCSICRRSSSDKLLSKEDEASVSDVDCRDTWTVIRGKFLAINAANMSCACPRSPKGLSPSAHLADGTTDLILVRKCSRVDFLRHLLRHTNKKDQFDHSFVEVYRVKQFRFTPRFQECGSEMDLRESRAGGKHFFCQICRENRACGCMSSQSNWNCDGEILPHTAIQVRVHCQLIKLFARGIEEQPVFEDLYAHCQLNNPPNHEP", "length": 649 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A5WWD5-1", "protein_name": "alpha-1,2-Mannosidase", "gene_name": "man1b1b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLPSTRKDFVSLTLSESGSYSNSKQWRRQSCWRKWKQLSRLQRSLILLTLMLLLVCGIATSPTLIGHWRGMNGDDVKNSFVVDLKNEYRSILPEPPSERKDFDRRGAFGLEKLLQGKVNVSGVLGDQNHGLDLKNADKGSEGQKPIISWRGAVIEEEQASDTDTKDTENQGDPASLALAESRLEAVREAFRHAWKGYKDFAWGHDELKPISKSYGEWFGLGLTLIDALDTMWILGLQEEFAEAREWVAKELSFDKNVDVNLFESTIRILGGLLSTYHLTGDNLFLDKAKEIGFRLMPAFSTPSKIPYSDVNIGKGTAHPPRWTSDSTVAEVTSIQLEFRELSRLTGDPKYKLAVMEVMKQVHKLDGKQDGLVPMFINTNNGLFTHQGIYTLGARADSYYEYLLKQWIQGGRIEQELLEDYLQAVEGVKKNLLKKSTPLGLTFVGELSHGHFSPKMDHLVCFLPGTLALGVHYGLPADHMELAKQLIETCYQMYAQMETGLSPEIAHFNMHDGSTQDVDVKIADRHNLLRPETVESLFYLYRLTRDKKYQQWGWEILQNFNKYTRVPTGGYTSINNVRDPSYTSPRDKMESFFLGETLKYFYLLFSEDPTLISLDKYVFNTEAHPLPVWPQAE", "length": 632 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A6NCW0-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 3", "gene_name": "USP17L3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGDDSLYLGGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSSETRVDLCDDLAPVARQLAPREKLPLSSRRPAAVGAGLQNMGNTCYENASLQCLTYTLPLANYMLSREHSQTCQRPKCCMLCTMQAHITWALHSPGHVIQPSQALASGFHRGKQEDVHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIHQIFGGCWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVKQALEQLVKPEELNGENAYHCGLCLQRAPASNTLTLHTSAKVLILVLKRFSDVAGNKLAKNVQYPECLDMQPYMSQQNTGPLVYVLYAVLVHAGWSCHDGHYFSYVKAQEGQWYKMDDAEVTVCSITSVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRAKQGELKRDHPCLQAPELDEHLVERATQESTLDHWKFLQEQNKTKPEFNVGKVEGTLPPNALVIHQSKYKCGMKNHHPEQQSSLLNLSSTTRTDQESMNTGTLASLQGRTRRAKGKNKHSKRALLVCQ", "length": 530 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A6NCW7-1", "protein_name": "Inactive ubiquitin carboxyl-terminal hydrolase 17-like protein 4", "gene_name": "USP17L4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGDDSLYLGGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSSETRVDLCDDLAPVARQLAPREKLPLSSRRPAAVGAGLQNMGNTCYENASLQCLTYTLPLANYMLSREHSQTCQRPKCCMLCTMQAHITWALHSPGHVIQPSQALAAGFHRGKQEDVHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIHQIFGGCWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVKQALEQLVKPEELNGENAYHCGLCLQRAPASNTLTLHTSAKVLILVLKRFSDVAGNKLAKNVQYPECLDMQPYMSQQNTGPLVYVLYAVLVHAGWSCHDGYYFSYVKAQEGQWYKMDDAEVTVCSITSVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRPATQGELKRDHPCLQVPELDEHLVERATEESTLDHWKFPQEQNKMKPEFNVRKVEGTLPPNVLVIHQSKYKCGMKNHHPEQQSSLLNLSSMNSTDQESMNTGTLASLQGRTRRSKGKNKHSKRSLLVCQ", "length": 530 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A6NDS4-1", "protein_name": "TBC1 domain family member 3B", "gene_name": "TBC1D3B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPLTAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEMKLKNPGRYQIMKEKGKRSSEHIQRIDRDISGTLRKHMFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQEHVVATSQSKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPITRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKQGDLPPPAKPEQGSSASRPVPASRGRKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGAVREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWVRAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHLESSQFPPGF", "length": 549 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A6NJZ7-1", "protein_name": "RIMS-binding protein 3C", "gene_name": "RIMBP3C", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAKDSPSPLGASPKKPGCSSPAAAVLENQRRELEKLRAELEAERAGWRAERRRFAARERQLREEAERERRQLADRLRSKWEAQRSRELRQLQEEMQREREAEIRQLLRWKEAEQRQLQQLLHRERDGVVRQARELQRQLAEELVNRGHCSRPGASEVSAAQCRCRLQEVLAQLRWQTDGEQAARIRYLQAALEVERQLFLKYILAHFRGHPALSGSPDPQAVHSLEEPLPQTSSGSCHAPKPACQLGSLDSLSAEVGVRSRSLGLVSSACSSSPDGLLSTHASSLDCFAPACSRSLDSTRSLPKASKSEERPSSPDTSTPGSRRLSPPPSPLPPPPPPSAHRKLSNPRGGEGSESQPCEVLTPSPPGLGHHELIKLNWLLAKALWVLARRCYTLQEENKQLRRAGCPYQADEKVKRLKVKRAELTGLARRLADRARELQETNLRAVSAPIPGESCAGLELCQVFARQRARDLSEQASAPLAKDKQIEELRQECHLLQARVASGPCSDLHTGRGGPCTQWLNVRDLDRLQRESQREVLRLQRQLMLQQGNGGAWPEAGGQSATCEEVRRQMLALERELDQRRRECQELGTQAAPARRRGEEAETQLQAALLKNAWLAEENGRLQAKTDWVRKVEAENSEVRGHLGRACQERDASGLIAEQLLQQAARGQDRQQQLQRDPQKALCDLHPSWKEIQALQCRPGHPPEQPWETSQMPESQVKGSRRPKFHARPEDYAVSQPNRDIQEKREASLEESPVALGESASVPQVSETVPASQPLSKKTSSQSNSSSEGSMWATVPSSPTLDRDTASEVDDLEPDSVSLALEMGGSAAPAAPKLKIFMAQYNYNPFEGPNDHPEGELPLTAGDYIYIFGDMDEDGFYEGELDDGRRGLVPSNFVEQIPDSYIPGCLPAKSPDLGPSQLPAGQDEALEEDSLLSGKAQGMVDRGLCQMVRVGSKTEVATEILDTKTEACQLGLLQSMGKQGLSRPLLGTKGVLRMAPMQLHLQNVTATSANITWVYSSHRHPHVVYLDDREHALTPAGVSCYTFQGLCPGTHYRVRVEVRLPWDLLQVYWGTMSSTVTFDTLLAGPPYPPLDVLVERHASPGVLVVSWLPVTIDSAGSSNGVQVTGYAVYADGLKVCEVADATAGSTVLEFSQLQVPLTWQKVSVRTMSLCGESLDSVPAQIPEDFFMCHRWPETPPFSYTCGDPSTYRVTFPVCPQKLSLAPPSAKASPHNPGSCGEPQAKFLEAFFEEPPRRQSPVSNLGSEGECPSSGAGSQAQELAEAWEGCRKDLLFQKSPQNHRPPSVSDQPGEKENCYQHMGTSKSPAPGFIHLRTECGPRKEPCQEKAALERVLRQKQDAQGFTPPQLGASQQYASDFHNVLKEEQEALCLDLRGTERREERREPEPHSRQGQALGVKRGCQLHEPSSALCPAPSAKVIKMPRGGPQQLGTGANTPARVFVALSDYNPLVMSANLKAAEEELVFQKRQLLRVWGSQDTHDFYLSECNRQVGNIPGRLVAEMEVGTEQTDRRWRSPAQGHLPSVAHLEDFQGLIIPQGSSLVLQGNSKRLPLWTPKIMIAALDYDPGDGQMGGQGKGRLALRAGDVVMVYGPMDDQGFYYGELGGHRGLVPAHLLDHMSLHGH", "length": 1639 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A7TZG3-1", "protein_name": "Selection and upkeep of intraepithelial T-cells protein 9", "gene_name": "Skint9", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESSASCLPGFFMSFLLLQNTVLTQAMRSDIKINIQVPDTEGLLLECTSGSLIPPAEMTWRDSNGNIIPHSTAFNSQDRDGLLYLKSSILLKNRAKGPITCSIYNVTTNQEKKRSIVLPDALFKSENMSLMSNKFSCPSIYLITIIFLNFLRGILVFCCLRRKPVCFRNLMSTVMEALYSKMGVCCLLIWECLLLVLYIAFLPIYVSFRSRAFLLDDTYPLYTNWLWNICIILTVIMVLFPGLILCLLWTLNCYGQVSSLPPTSMELSTKDSEQNSSKSDDSQENYDVNCKILETCESKIFSQHQESCEDDTASTLFIS", "length": 319 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A7XV14-1", "protein_name": "Selection and upkeep of intraepithelial T-cells protein 11", "gene_name": "Skint11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEPSASCLPGFFMVCILLKITVLTQVMSLDIQINTQIPDTEEGVLVECTAESLFPPAEMTWRDSKGNIIPPSSTFDSQDRAGLLCLKSTILLKNRTEGPITCSIYNKTTNQEKRRSIILSDVLFRPQYMSLMSNNLLYLGIYLIFILFLNFLKGILFCLTKRLVHFRKRMIKIKKVWSNKTRACCPLIWEFLEIVLFIAFLPLYLMFRIRVFTLDEAHILYNNWLWKVCKTLIAMMILFTVLILFLLWTLNRYGKMPCLSSMNIDVSTHDAEQNSSKSAKFQENYDVAGQMILETYEETIFCQHQESCEEYNYDPLLLSSLDALGTCEDEKFSQHQESFEEDEDLQSFSDFKIELYSKLGNLTH", "length": 364 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B0BMZ6-1", "protein_name": "Cilia- and flagella-associated protein 119", "gene_name": "Cfap119", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MITPRSSQSLEMKVQTELEHSPKLQEEPDRSPSLVDSSVIRIGTDEQNESPAEATSSPVEVAEDPGANLFPPPLPQPRICMWKYLDIHSMHRLEKAATVEEMREVLAELLELGGPEQSLRDAIILDLFSHALIFCRQQGFSLEQTSAACALLQDLHKACVATPLGNVEECYRYFTSVLFCHGVRRPPFSIDLFKEEQLLALADYVVNTYFRHFKLYKYVFTPQVRLDLSLSYMGLQSLHLWPEEKEDEEATVEQAATPQEEEPEAVTEAEQQPSEVCILQTYIKCQLNKELRQLQQLVEERLKESEERLSNRLAALERPYQTPPSKGKSKAK", "length": 332 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "B0G0Z9-1", "protein_name": "Probable polyketide synthase 6", "gene_name": "pks6", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNNLKNIDLIEKGVAIVGIGFRIPSGNNENSICSPDDLFNNLKNGFDGVSSTSERWSDNYHKLGEISSPNAGLLPLNEWKSFDPLFFGINPSEASLIDPQQRLLLKCTWEALEDASIDPISIRGTNTSVFIGASNIDYQHTNKHQDSVLKNAIAQSTCAISNRISYCFDFNGPSLSIDTACSSSLNAVSQGYHSILNGTSDISIVGGVNLILDVEMTKAYSYLSMLSKTHGKCKAFDESGDGFTRGECVGVVVLKNLQDAIKDGNRIYCVINGSSSNVDGNGNMDKVNFYSPSKQSQFNNINSAFKSTNDKLSINDIQYIEAHGTGTKTGDPIETEAISMAFKNRDKSAPILIGSIKSNIGHCEAGSGVASLIKCCLMFKYQCFLPNIHFKNPNPLIKFNEWNLKVVTSPIPFNKRNNEKPVSMMINNFGVTGSNCCLLISEFKNNNNFKENINLESQSVNDRVLIPFSANSSNSLNQYQSKFKNIINNQFNFIDFTAIQIYSKSNYLYQRSVVIASNSNELFENISNKKQIQTKNSIISNMSFKGKNPITIFVFSGQGSQYPKMALELYNNEVIFKKSIDLIDSKLSKYYGFSVWEKVKTIKDDDLTSIHDPIFAQPALCMISVSLFELYYHWGVNPSFILGHSLGEISASYCSGMIDLDTFCYTVYQRSIAQSKTNGCGRMLSINISDEEFKSMYSQKYPQIEIACYNSPQSIVVAGNESILNEISKELKEKEIFTAMLGSLSSFHTSSQQSTKDSILQLNIESNQPKVPIFSTVTTNLFNESNRFNSQYVYDNIIKPVKFTQTISNIYKHIESNQLDNDIVFIEIAPHPTLSFYIKQMVPSSLNESVSVYSALHKKKNDVEEFQQTISNLYCQNGYNINFKCQFNNKKSNLNIELPLYQWSDELYFAQNQVLEQHRKGGPPIDHLGLSNSYYSPFKNSYKTLIDINYKPFQYLKGHMVKGKYYFPGCGYIDNIIQLYKNQDIFISFIEFKTPLILIEGINQYLQTNIQQTGKSEYRAQFHFKDHKSNEWIQSSNSNFQLLDHGNDIPSNYNIKEIIKNKCNLSKLTKNELYKNIKSKTGLNYTGVFQGVTECYIGDNCTLSVVSLESQTNSFLNIPILDTCLHGMLILINDQCQIVFDKAIGFKYYSSNIPADFKENKDSFYVYSNLRPRVGGDSYHGTIIVMLSDGSVLYEIEEVVCKSLIPIKDSLKIEYPNDELYKVHLQSKDSPIPTPSSFKSIIYENDFFQSSLNIPEDLFKYISTLFYKDIIKRCPEININKINSHSVNEIISSFSKISKHERLFRFVFETIKENGILNSFEEKDDTYFEFNKVIIKSSRIISKLLFPLENDNDNEDLPQSLFQNGLMDKIYKCSYLRKKNQVISHVIKHSIKEIINNNIIIRILEFGGGTASLSVEVIEEIVTLLQENPNYQVEIEYTWSDISPAFIADAKNKINKIINDAAITNGLNVIYHPLTIGESLIETQSIKPSYYDFVIMSNVLHVVKDIKQAVEQMYQLLTTNGQLVFLEPPYKSVLNDSIVGSFEQWWSFTDTDIRKDRCGMPQQSWYQLLNSCNFKDIVMSKECIFFGSVIQAQKPPISLLNSQPKYDNIIIYGGSINSSFVENIKLDSNSKSLFQIETIQEFNKLISKSTITNDSIVYFIKTLETLSLDNFKQITLEYIEINQKLLQINSLCKHVLIVSDSRKTNYLASSAIGAARYFDEFPLLKLHTLDFDYDSTQNYINSKNNKMVQFINILTDSKTNVHKEMIIINNKVYYEIVQKEKNLKLKYNSESFENQNNLMCSLSPNLEYQLQSKQIKLRDNQVEVKTIATGINYKDYLNFSGSNSNGDDNTGLPQFGYEFSGIITRVGNNVKDYKVGDNVFGLSNSCTSSHIVTNFKKIQIKPSKISHIEASSIPIDYLTSFMSLFNVGSLNIEDNESILIHLGRDGFGLSTFEILKWKGFKSNLFVTVNSDKTKQYLLKKYGDLITGIYSNTDKSYVAEIKNKLIKLGSKKKGVDLILNTLPSDFMDSNFKLLTKYGRIIDLNSNHLNQSEFLKNINFKYNHGYHNFELSLFQKNKILKCLNEISNAIENGELKTIPIKEFTNLNIKDAIKYITNGNIEKITVSHDHEIYSDIIYRYLDEKEFSILKSNYQINSNNLGKNILITGQSGIILEILKWIIKYSNINTIENVIILSRSSLKWELELLINQTKLSNNNIKFHFKSVDVGDSEQVDNAINDILNENQQIRNIDSIFHFAFQQIACKVQEINMKHLNISHGAKSMGAINLHNQSIKRNWKLINFVMASSALSFIDSTDQCTYACANTLLDSFSKYRVSLGLPSTCINLGLIESTGFVSKNESISVFLDGNGIIPTPINRVLGLLDLQIQNASKFTNSMISNFKPSKFKNNQQISLFLKFDYLMNLKNNSEQTKKENTGNKNIDELFIEKVSELFSMDESKINKNLRLIDYGADSLIIVQLKNWIDKEIGINLITIQQLQNNTINISIKMILNSLMKNNQNKYLPSNRIDYWKNEMKFEESIKPIPNEIRSRNNNSGKIILLTGTTGFLGGFLLFNMLRLDSCKLIYCLIRNKSKSSYPLDEIINNLKYHQLYEKLNKSQISKIIPIIGDLSMNKLGLSNDDYETISKNVNLIINPGADINQKSSYQDCKLVNVNGVKEIIKLSLSSLKQRIPIVNFSSFSVFFNQSLDKNFDESVLPSIDNIDNLPTEYMKSKVVGEYILLEASKNYNIPSILIRPPSIFLNPETGIGHSSDLTLLMIQSCYELGYCPNQILNGFILINTITWLSNNITNIIMNDNCWTNSKMNIYNVHGKQIQSSLIIKPLEKHFNCKQINNNDWIDMVNNSNKKSCIKLKSFHSLENIFKSENKGYKSNESQSISLSTKSLLESMGSYNTDLKITDKMIISHIKHIFK", "length": 2924 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0G100-1", "protein_name": "Probable polyketide synthase 7", "gene_name": "pks7", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNNFKNINLIEKGVAIVGIGFRIPSGNNENSISSPDDLFNNLKNGFDGVSSTSERWSDNFHKLGEISSPNAGLLPFNECKSFDPLFFGINPSEAPLIDPQQRLLLKCTWEALEDASIDPISIRGTNTSVFIGSSNIDYLHTNKHQDSVLKNVIAQSTCAISNRISYCFDFNGPSLSIDTACSSSLNAISQGYHSILNGTSDISIVGGVNLILDVETTKAYSYLSMLSKTHGKCKAFDESGDGFTRGECAGVVVLKNLQDAVKDGNRIYCVINGSSSNVDGNGNMDKVNFYSPSKQSQFNNINSAFKSTNEKLSVNEIQYIEAHGTGTKTGDPIETEAISMAFKNRDKSTPILIGSIKSNIGHCEAGSGVASLIKCCLMFKYQCFLPNIHFKNPNPLIKFNEWNLKVVTSPIPFNRKNEKPVSMMINNFGVTGSNCCLLISEFKKQDYEPYENNYKSNNKNILIPFSANSSNSLNQYQSKFKNIINNQFNFIDFTANQIYSKSNYLCQRSVIAASNSNELFEKILNKKQIQTKNSIISNMSFKGKNPITIFVFSGQGSQYPKMALELYNNEVIFKKSIDLINSKLSKYYGYSVLEKLRSIGDDDTTSIHDPNISQPAVCMISVSLFELYCHWGVNPSFILGHSLGEISASYCSGMIDLDTFCYTVYHRSIAQTKTHGNGRMLSINISDEEFKSMYSQKYPQIEIACYNSPQSIVVAGNESILNEISKELKEKEIFTAMLGSLSSFHTSSQQCTKDSVLKLNIQSNQPKVPIFSTVTTNLFNESNRFNSQYVYDNIINPVRFTQTISNIYKHIESNQLNNDIVFIEIAPHPTLSFYIKQMVPSSLNESVSVYSALHKKKNDVEEFQQTISNLYCQNGYNINFKCQFNNKKSNKKIDLPLYQWSDETYFAQTQTLEQHREEGPPIDHLGISNSFISPFNNSYKTLIDINNKPFQYLKGHMVKGKYYFPGCGYIDNIIQLYKNQDIFISFIEFKTPLILIEGINQCLQTNIQQTGKSEYRAQFHFKDQKSNQWTQSSNSNFQLLDHGNDIPSNYNIEEIIKNKCNLSKLTKNELYTHIKSKTGLNYTGVFKGVTECYIGDNCSLSVVSLESQTNSFLNIPILDTCLHGMLVLINDQCQIVFDKTIGFKYYSSNIPAYFKENKDCFYVYSHLKSKSADSYHGSIIVMLSDGSVLYEIQEVVCKSLIPIKDSLKIEYPNDELYKVHLQSKDSQIPTPSYFKSIIYENDSFHSIVNIPEDLFKYISTLFYKDIIKRCPEININKINSHSVNEIISSFSKISKHERLFRFVFETIKENGILNSLEENDDAYFEFNELVIKSSRIISKLLFPLENDNDNEDLPQSLFQNGLMDKFYKCNNFKKKNQIISHVIKHSIKEIINNNIIIRILEFGGGTASLSVEVIGEIVTLLQENPNYQVEIEYTWSDISPAFIADAKNKINKIINDAAITNGLNVIYLPLTIGESLIETQSIKPSYYDFVIMSNVLHVVKDIKQVVEQMYQLLTPNGQLVFVEPPYKSILIDSIVGSFDQWWSFTDTDIRKDRCGMSQQSWYQLLKTCNFKDIVMSKECIFGSVIQAQKPPISLLNSQPKHDNIIIYGGGNNSRFFENIKLYSNSKSLIQIETIQEFNQFINKSTITNDSIIYFIKTLETLSLDNFAQITLEYIEINKKLLQINSLCKHVLIVSDSRKTNYLASSVVGAARYFDEFQQLKLHTLDFDYDSTQNYINSKNNKMVQFINILTDSKTNVHKEMIIINNKVYYEIVQKEKNLKLKYNSESFENQNNLMCSLSPNLEYQLQSKQIKLRDNQVEVKTIATGINYKDYLNFSGSNSNGDDNTGLPQFGYEFSGIITRVGNNVKDYKVGDNVFGLSNSCTSSHIVTNFKNIQLKPSKISHIEASSIPIDYLASFISLFNVGSLNIEDNESILIHLGSDGFGLSTFEILKWKGFKSNLFVTVNSDETKQYLLDRYGDFISGIYSNTDKSYVTEIKNELIKLGSKKKGVDLILNTLPSDFMDSNFELLTKNARIIDLTSNHLNQSEFLKNINFKYNHSYHNFQLSLFQKNKIQKCLNEISNAIENGELKTIPIKEFTNLNIKDAIKYITNGNIEKITVSHDHEIYSDIIYRYLDEKEFSILKSNYQINSNNLGKNILITGQSGIILEILKWIIKYSNINTIENVIILSRSSLKWELELLINQTKLSNNNIKFHFKSIDVGDSEQVDNAINEILNENQQITNIDSIYHFAFQQITCKVQEINMKHLDISHGAKSMGAINLHNQSIKRNWKLINFVMASSAISLIGSTDLCTYACANTLLDSFSKYRVSLGLPSACINFGSIESTGFVSKNESVSVFLDGGGFHPTPINQVLGLLDLQIQNSGKFTNSMLSNFKPSKFKNNQQISLFLKFDYLMNLKNNSEQTKKENIGNKNIDELFIEKVSELFSTDESKINKNLRLIDYGADSLIIVQLKNWIDKEIGINLITIQQLQNNTINISIKMILNSLMKNNQCGREI", "length": 2513 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0G101-1", "protein_name": "Probable polyketide synthase 8/35", "gene_name": "pks8", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNNLEIINLIDKGVAIVGVGFRIPSGNNENSICSPDDLFNNLKNGFDGVSSTSERWSDNFHKLGEISSPNAGLLPFNECKSFDPLFFGINPSDAHQIDPQQRLLLKCTWEALEDASIDPISIRGTNTSVFIGSSNIDYQHINKHQDSVLKNVIAQSAYAVSNRISYCFDFNGPSLSIDTACSSSLNAVSQGYHSILNGTSNMSIVGGVNLILDVGMIKAYSYLSMLSKTHGKCKAFDESGDGFTRGECATIVVLKNLQDAVKDGNRIYCVINGSSSNVDGGGHMDKVNLYSPSKQSQFNNINSAFKSTNGKLSINDIQYIEAHGTGTKTGDPIETEAISMAFKNRDKSTPILIGSIKSNIGHCEAGSGVASLIKCCLMFKYQCFLPNIHFKNPNPLIKFNEWNLKVVTSPIPFNKRINEKPVSMMINNFGVTGSNCCLLISEFKKQDYESYENNNNNKSNHKNILIPFSANSSNSLNQYQSKFKNIINNQFNFIDFTANQIYSKSNYLYQRSVVIASNSNELFEKILNKKQIQTKNSIISNMSFKGKNPITIFVFSGQGSQYPKMALELYNNDEIFKKSIDLIDSKLSKYYGYSVWGKLTTIKDDDLTSIHDPIFAQPALCMLSVSLFEIYCHWGVNPSFILGHSLGEISAAYCSGMIDLDTFCYTVYYRSIAQSKTNGCGRMLSINISDEEFKSMYSQKYPQIEIACYNSPQSIVVAGNESILNEISKELKEKEIFTAMLGSLSSFHTSSQQCTKDSILQLNIESNQPKVPIFSTVTTNLFNESNRFNSQYVYDNIIKPVKFTQTISNIYKHIESNQLNNDIVFIEIAPHPTISFYIKQMVPSSLNESVSVYSALHKKKNDVEEFQQTISNLYCQNGYSINFKCQLENKKSNQSINLPLYQWDDELYFAQTQTLEQYTKEGPPIDHLGLSNSYYSPFKNSYRTFIDINNKPFQYLKGHMVKGKYYFPGCGYIDIIIQLYKNQDIFISFIEFKTPLILIEGINQYLQTNIQQTGKSEYRAQFHFKDQKSNEWIQSSNANFQLLDHGNDIPSNYNIEEIIKNKCNLSKLTKNELYTQIKSKTGLNYTGVFQGATECYLGNDCSLSVLSLKSQTNSFLNIPILDTCLHGMLVLINDQSQIVFDKAIGFKYYSSNIPSDLKEYKDSIYVYSNLKPKNADSYHGSIIVMLSDGSVLYEIQEVIFKSLIPIKHSLKIEYPNDELYKVHLQSKDSQIPTPSSFKSIIYENDFFHSALNIPEDLFKYISTLFYKDIIKRCPEININKINSHSVNEIISSFSKISKNQRLFRFVFETIKENGILNSLEENDDAYFEFNELVIKSSKIISKLLFPLESDNDNEDLPQSLFQNGLMDKIYKCSYLRKKYQMISHVIIHSIKEIINNNIIIRILEFGGGTASLSVEVIGEIVALLQENPNYQVEIEYTWSDISPAFIADAKNKINKIINDAAITNGLNVIYRSLTIDESLLENQAIKPSYYDFVIMSNVLHVVKNIKQAVEQMYQLLTPNGQLLFIEPPYKSVLIDSIIGSFEQWWSFTDTDIRKDRCGMSQQSWYQLLKTCNFKDILMSKECIFVGSVIHAQKPPISLLNSQPKHDNIIIYGGGGNLSFVENIKLDSNSKSLIQIETIQEFNQLLSQSTITNDSIIYFIKTLETLSLDNYKQITLEYIEINQRLLQINSLCKHVLIVSDSRKTNYLASSVVGAARYFDEFQQLKLHTLDFDYDSTQNYINSKNNKMVQFINILVDSKTNVHKEMIIINNKVYYEIVQKEKNLKLKYNSESFENQNNLMCSLSPNLEYQLQSKQIKLRDNQVEVKTIATGINYKDYLNFSGSNNNNGDDNTGLPQFGYEFSGIITRVGNNVKDYKVGDNVFGLSNSCTSSHIVTNFKNIQLKPSNISHNEASSIPIDYLTSFMSLFNVGSLNIEDNESILIHLGSDSFGLSTFEILKWKGFKSNLFVTVDLDETKQYLLDRYGDFITGIYSNTDKSYVTEIKNELIKLGSKKKGVDLILNTLPSDFMDSNFELLTKSGRIIDLTSNHLNQSEFLKNINFKYNHGYHNFQLSLIQKNKIQKCLYEISHAIENGELKTIPIKEFTNLNIKDAIKYITNGNIEKITVSHDHEIYSDIIYRSLDEKEFSILKSNYQINSNNLGKNILITGQSGIILEILKWIIKYSNINTIENVIILSRSSLKWELELLINQTKLSNNNIKFHFKSVDVGDSEQVDNAINEILNENQQITNIDSIYHFAFQQITCKVQEINMKHLDISHGAKSMGAVNLHNQSIKRNWKLINFVMASSALSLIGSTDQCTYACANLLLDSFSKYRESLGLPSACINLGSIESTGFVSKNESISEFTDGIGYVPTPINLVLGLLDLQIQNAGKFTNSMLSNLISSKFKNIQQTSLFLKFDYLMNLNDNSEQTKKENIGNKNIDELFIEKVSELFSTDQSRINKNLRLIDYGADSLIIVQLKNWIDKEIGINLITIKQLQNNTINISIKMILNSLMKNNQI", "length": 2514 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0G110-1", "protein_name": "Acyl-coenzyme A oxidase", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MYKNRIEIIKKHLEVNNSQTTNNKDEVLEKELFNSIDTNINVGELKLLIDSVEESKYKDETREFIRNHPKFKENFIGLDMATYRQLVLEQCAAIANRGLIHFTDIKNNLHRYIGALEMFALYNNNILTKLSVQYTLFGGPIIFLGTSRHEKYIEDANTLKTMGCFAMTEIGHGSNVRGIETTAHYDKQTKEFIIHSPTPTSEKFWIGCAYLHATYAVVFANLIIDGTNYGIHAFIVPLRCPKSGAIMKGITIKDCGHKLGLNGIDNGQIRFDQVRIPRENLLNKYSDVSEDGVYKSQFNTPIKNFAATMSPFIVGRMAITKGCSGAAKTSLSIAIEFSHIRKQFGPSSNKELPLITLSSQQRRLMAPLARTILFDLYIQRLTNELCQEKLPASIHAHCSGIKAVYSWFCVAALQTCREACGGQGYRSANRIAEFKNDCDIICTYEGDNTVLMQQLAKYLLGVKQKQTNTTTNRIYLDGEDAKSLFFNFSNINQLFETREEMRLAELKQIIDNSKESAYFAFNNAIPWAVKLGFAHMTKIVFQNSINTLKLKNVKPLTHLIMLDALVSIEEDLGWFVSNHLISPNVAQSIPFLIQDLCFEVTKVSKQIIASFDIPENCKPSSKDLISDLF", "length": 629 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0G138-1", "protein_name": "Probable polyketide synthase 21", "gene_name": "pks21", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKLENKEIAIVGIGFRIPQGKESINNGSVSHLWNNLKNGFSGIVETSERWSDNINLLGEVNNKFGGLLPLKEWSDFDPVHFAINPSEVPLMDPQTRLLLKCTWEALEDAFIDPIDIRGSNTSCFIGCSTLDYSTTNRDFNETSENYFASNVLHTISNRLSFSYDIRGPSMTIDTACSSSLNSIAMGFQSIQNGTSNLSIVGGVSLLLDPYISKSFSFLNMLSKKGKCKPFDSEADGYIRAESCGIVILKPLSDAIRDGNNIYCVINSFSSNVDGGGLNDKSNFYSPSKQSQSDNIKLALKSANMKASDISFVECHGTGTPTGDPIEVEGVSMALNSSKTSTPSKPLLIGSLKSNIGHSEAASGVASLIKCCLMFKNKHYAPNVNFDQPNPKINFKDWNIKVVTEAIPFTNNNEKPVSMVINNFGVTGSNCCLILSQFIEQSINQNGNGHSYPAESQQQQQQRFLIPFSANSVKSLKNYEDLIINDIKISTNSFKEFVKNQIYSKSKKLYQRSVLISSNWDQLKTKNKYFKTNNDKSSNITIKRNQPLVVIVFGGQGSQWNKMAQQLYECEPIFRSSMDKFNKELSKYYGYSVLDKLRSIKDDDIISIHQPIIAQPSILMLQISLFELYKHWGINVSFIVGHSLGEIATSYCSGMVDFQTVCKLIYHRSISQNNTNGCGKMLSVNISHSEFIELYSNKYPTIEVACYNSPTSIVIAGNENILKEISLNLKENNIFCAFLGSLSSFHTSSQHSTKNEILPLDIPSKQSRIPTFSTVTTNLFNHETTPFNSSYVYENIIQPVRFSQTISNLYQHIENNKLGNELIFIEVSPHPSLSFYLKQMIPKSSSYFNSVSVLTSTNKKNSNDLDEIHSTISQIYCLGYDVNFKCQFNHNDDDVSSIRNSKVNISLPNYQFDEQHYWKVDINFEQYRLNGPNVFNSLGKSMINYSSNNKSYESIIDINRNPFKYLKDHIVKGKYYFPGIGYADNIMKLYPNQDIIINNLEFLAPFVLKENVKHTLQTNVYQLGNTDYRVTFNIKDNKTNQWVQTCTGNFQLISLKDNNNDHSSKYDINQLLSECNFTTLSKQEVYKHSRSITGITHLGAFQGIEELYFGNDCIISKIQVNTENFDIDGKPVYQTYDKSFFNTALLDSCSQTIVGFITNSSQFVFERLEGLKVYSENIPTDKLKYKNIYCQAKFISLESDSYKSSVLVLLEDGTKLLEMDCISLHSTLPLLNSLLINNPTTELFTNNLQCKDSLVNILSIDNNQTFSSISSSNTVTEIIKQTIKPIINEKIVFRILQSFSDLELSKQIIETLNQIFDDNSLQEIDIEFTIIDNSNDKLPTLHDSSLIFKNDITQLKPSYYDIIINNNNDGDDETIIKSIFNILSSNGLLLIIGDDIGDKYNIDSLINLGFNENKIQKSNKVIQSQKSTILSNELTVVPNNKNDNIIIYCEKESKYTNEFMKLISNNHISCKQTIISNINEFNQLLPSITNDSIIYFIKSMEQLEMNNFKQITMEYIEINQQLLKHSLTCKHVLITIDSQIKNYLSSSIIGTARYFNEFPSLNLYSIDFDNQLSISSLLNKIINQLIENSNNHIQREYIIRNNSIYYEILKNEKNIKSNFNSNSFEDNDFMTLLDSTNLEYKLASKPKKLKKNQIEVKVLATGINYKDYLIYRGLVVIDENVSISKNPLGLEFSGIITRISNENQNCEFKVGDNVFGIACDTTASHVIADVLYVSHKPENISHVEAASLPVIFSTCLHGMFNIGNFNIDDDEVILIHSATGGIGLATLEILKWKGHKSPIFVTVGSKDKEQYLIDNYGSFITGIYSSRNKNYVNEIKSKLNQLYGTTGKFNGVDLIINTLPNEFTHSNFLCLKERGKIIDLSITHLNNNEFLNFNNFKFNKSYHNIELMHINKKVVSRLLKSISNALNENKLKPIPITTFQIEDVKEAIEYINQRKHIGKIVLDHSCSNGSIGSDGLLNQLIESDNNEKNHTILKYDFKIDTKNIIGKNIIITGQSGIILEILKWLIKYSPTESFENIIILSKSSLKWELELLINKTISRKDNNTKFHFKSVDVGDPIEMRKSINQILLENPNIDNIDSIFHYAFAQITKEVEEIDIESLDISHNAKTMGAINLHEISIEKSWKLKQFVMASSIASLFGSFNQCSYVSANLVLDSLSRYRKSIGLPSTCTNWGAIKSAGFVSRNELVSKMLDDQGFIPIPTNIILGSLDLQLQNSNKNSNLIVSKFNYDSIKKLSSETSTFQRLDFILNSIKEKDNDSNGGENSVSESIQTKILNKISELLSIEQSKINTDIRLSDYGADSLTSVQLKNFIDKDIKSNVITLQQLQNNTIDMNIQTILEQIKKLDSNETKGKSKNIIKKDSAPTLDYWRNEMKLDESIQAIKMNPIDFRNDSKVFLTGATGFLGVHLLSNLIKSPNCSVVYCLIRNKKSEPNPINAIINNLKHHKLYHFHNEFELSKIKVIVGNLASPLLGLSKLDFDYISNQINLIINSGADINLASNYEESKVVNIGGFIELIKLSTTGDYQKPIVGFSSVSVFFNASNCKEFDEETVIPTIENINNLPGGYMKSKVVVENLLREVAKRGIPSMLIRPPIIFSHEETGIGHDSDFFQLIIQSCYAVKKYPKIDKNILTSPIGWISLNTIKMIGNEKCWNKSSSNQLNIYSLNSEVSAMNPSFSFLEKQYGCEMVEYEQWKNIINQSKILSCVKLKTFHSLDDLYNIYNLGNGFGVSKKTKELLQSMNSYEGGMVNEKMIQNHINYIFKN", "length": 2779 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0G149-1", "protein_name": "Transmembrane protein 184F", "gene_name": "tmem184F", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MLSHINIIYIIWILLFFFTCLISFFLVNRHLVNYSSPNVQKNVVRIVMFLPLNSGLSILSSIFPGIAIFNSLVRNCYMAFTAHCFFSMMTNSIGEKNMLDLFESQGKMKFLCCKVMKLNRKLFNTLRFGSIQFFIVKIFCSIATITCISISEEVHSILNVQSFAPYEFLISLVASIFCTISLSIFLAISKEKLSQYWPMTKYRIMIFIFFIEQFEYLFFALIFLRGPFFLGFKNSFDQTIFILHFTVVVTMFLFSIVYLFIYSYKNYRNKASNEPLVGRNFKDSFGLLNYLDVLNPKDLFIDFASIFKTNNNKFKELVEENGDKKPKKNIEDQNQENSNDQPLSIQMA", "length": 348 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0G188-1", "protein_name": "GATA zinc finger domain-containing protein 16", "gene_name": "gtaP", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNSYQIQNQPYQQIQNTHPSFQQVQPMQVPHLQQQQQHQTMIAQQQHTPPQQHTPPQMNMIQQHTQPMLSQPQISLQMQPPSPILASQQQQQHMQSSPILASSNLTNSNNASQTTLPIITSKLLLKKEPIDQEVVNSTHKTTTTNNKPPKQSKRKEKERLEEEKQTVAQQQQYQPPFIPLASNESNSDNPFKGSHAYGVSTTPYGNSQFNNNNNNNNNNNNNNNNSNNNSNNNNGNNNINNNNNNSNNNNNNNSNNNNNNSNNNNGNNNNNNNNNNNNNNNNHNTNNNNSNSNNNNNNGYQQDKKDDYSMMIWSEVGRKINILIRTTSKATKGTPISTQEIAEAIGASNGVTADLVELIKSINDPTYVRKLPPSSISNTPTMGSQSGGMVYNSSPMLSPSTMSPILQHGNYQMGGDMYFGGNNQFSGDKQSALNNVKNSKGGNTNNSGGGSSSGGTNDTQAKKPARRRKMRYGGTELSCHTCGVTNTPEWRRGPNGAKTLCNACGLAWAKSVKSEKQKELLANSTGVNITEPKKAQKRKKESSDNNNNNNNSSDSNKVLKSDDGSNNTNLTNDDDNGYPSSPNSSNSTSPSSHNINNNNNNNNNNNNNNNNNNNNNNNNNNNNIGNNNNNNINNNNTTNSITTPTTTPFPTTIPAMQIVSQLPVMVPQTQQQPHMSGNIISFQALHQNSGYQHYK", "length": 695 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0R191-1", "protein_name": "C-X-C motif chemokine 11-6", "gene_name": "cxcl11.6", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MKTLAAFLLLSCLIAGEVNGQDRSSRARCFCVDKGLNMVLLKNLDKVEIFPPSPSCNKHEIVVTLKNGAGQKCLNPDSKFTKNVVLKAIGKRMQQSVPHSTTTGTVKSSMTSSTSAPTAFK", "length": 121 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "B1AV09-1", "protein_name": "Leucine zipper protein 4", "gene_name": "Luzp4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MANHEDEIRQLRYLEAANSEEEYNEENDIQSESSRGQAFFPGHPRGRGHRRDSRGRNGHFFRQRFSANHPLLHLTRQVNLESLTRRNGNQSEERQLQQERIQLFFRSLHGLSQSHDHHIGRSHGHYSRRSRNRFRRAPVHSERSHVYSGRTNNYTDRPHHDLSDRPHNQLSVRPHPDLSGRPLHDYSGRPHQNHAVRLQHGHSDRYHLTHTERVLPNNSGIDHPGHTERDNQVQRGRAHDNQSGLAHHNHDGRSHHDHSGRAYHGHARRAHNNQSWRSDNNQSWRDLNQSWRGQNNQSQRGHDNQSQRGHDNQSRRGHDNQSQRGHDNQSQRGHNDQSWRAHNIRSRRDRYHTSLRSSSIQSWMLHERERYHGPRGRNGPRDASPPGSEPEIDRSSAIRERTDYLWVQEHRRNETVELNVGLEDGYSSAEESDESLDRLTCRSMLDTLY", "length": 449 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B1AY40-1", "protein_name": "SSX member B8", "gene_name": "Ssxb8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "METVSFCEKVPMEVLYEPKNICKAFQDISTYFSDEEWGKLTQWQKSAYVYMKRNYIRMTDLGVTVNQPVFMSGKEQDKQSLVEGIEVHDSEDECFEGSFGVTPIKQMKLTPVTISIHNVEGSLASGENNSNLAETSGIQVNVWSHRLRERKYRVIYEEISDPEEEEDDDY", "length": 170 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B1AYI3-1", "protein_name": "Predicted gene 13272", "gene_name": "Gm13287", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLPVHLFLVGGVMLSCSPASSLDSGKSGSLHLERSETARFLAELRSVPGHQCLRDRTDFPCPWKEGTNITPMTLGETTSCYSQTLRQVLHLFDTEASRAAWHERALDQLLSSLWRELQVLKRPREQGQSCPLPFALAIRTYFRGFFRYLKAKAHSACSWEIVRVQLQVDLPAFPLSARRGPR", "length": 182 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B1AZM5-1", "protein_name": "Predicted gene 12886", "gene_name": "Gm12886", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVLPCSLWLLSVCLLSWCCDAKLPVALDPESESVPKPPVLKTATEIAAIVVFMKTSNETPKSGTYGQSLQDGKNKIKDVEKEVLDACSQLCQSLAQDPNLHHGYILRAYFKEHQFLCCF", "length": 119 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B1B0R2-1", "protein_name": "Spindlin family, member 2D", "gene_name": "Spin2d", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESSKLTKKRAGRKRQRSRSPALPKRNIVGCRISHKWKEGDEHITQWNGTVLDQVPVNPSLYLVKYDGIDSVHALELYKDKRVLSLKVISKRVVSSGVTDSSFADAIVGKEVNHLFEGEHGSKEEWRGMVLSQAPILDNSFYITYERDPILYTYQLLDDFKEGDLQIMEGFSDPPSLDIDLELVDGLIGKHVEYTNDDGSKRDGLIIYQIETKPRVYLVKYEDDVHIHVTHLEKEL", "length": 236 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B4F7F0-1", "protein_name": "Claudin", "gene_name": "Cldn6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASTGLQILGIVLTLLGWVNALVSCALPMWKVTAFIGNSIVVAQMVWEGLWMSCVVQSTGQMQCKVYDSLLALPQDLQAARALCVITLLIVLLGLLLYLAGAKCTTCVEDKNSKSRLVLISGVIFVISGVLTLIPICWTAHAIIQDFYNPLVADAQKRELGASLYLGWAASGLLLIGGGLLCCACSSGGTQGPSHYVARYSSPVPHSRGPSEYPSKNYV", "length": 219 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "B7ZW38-1", "protein_name": "Heterogeneous nuclear ribonucleoprotein C-like 3", "gene_name": "HNRNPCL3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASNVTNKMDPHSMNSRVFIGNLNTLVVKKSDVEAIFSKYGKIAGCSVHKGFAFVQYDKEKNARAAVAGEDGRMIASQVVDINLAAEPKVNRGNAGVKRSAAEMYGSSFDLDYNLQRDYYGGMYSFPARVPPPPPIALAVVPSKRQRISGNTSRRGKSGFNSKSGKRGSSKSGKLKGDDLQAIKQELTQIKQKVDSLLENLEKIEKEHCKQGVEVKNAKSEEEQTSSSSKKDKTHVKMESEGGADDSVEEGDLLCDDDNEDQGDNQLELIKDDEKGAEEGEDDRDRANGQDDS", "length": 293 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "B8JKF6-1", "protein_name": "BTB domain containing 35, family member 13", "gene_name": "Btbd35f13", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRFLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSGYFANILKGTWRESHHGAINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYVLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "C0HKD1-1", "protein_name": "Spermatogenesis-associated protein 31F1B", "gene_name": "Spata31f1b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSTMCFLWDTECPLYVYFCFFIIVLIVWQVRQNYQGLKCENRRSCCRRHQKVRQRAKDAASRARRLSREEDEKPCELLSIMKSQSWVPKQGNVRQLLCLDPSCQICEATTLEIRQLLQSKKSQISPALLGLPQRAACLEMPISSESFEWNQDFYSRYSTNSPVVPGNQTLTQLTEELTESTNADGVLLCWTDPLQIGQEFHLADMPMASETLVSPGLEEPVVLMNEEDTVHSNLNYIQQLQDHEALNSQIPFQTLTPQLTVTHPMAVSIVTDAPQPFLSPEVLRLLEIHVKKLMHFQRWGLPRRVEESLKQFMPNPPVYLPPEHNQPVSFILNTSSQDCVHRFEGISPETWYSYMDGQPIQTFWVSEWSSGDQGQRLSCKPIPSPVEKPLLTPDYELLHDLCLSPEGQVDGSQSNLQKKFTQLFCGLPSMHSESLGSTFLCTQGVSKNTLKPPYKEPHFLKVSPPIPLPEAAPPPSSTSPNESLDEPQRAQIGGVPFLTLSECKTLEWHLLQRQLQLQWGLPAVIARPPRVQSHTQYKHKPWNKAKPRETLKFFGPGKPFSALTRELFFIPQHARRLLEFHLQKRLIHLRWGLPQRIQRSINMLLSSTDLQSLPCGGSRLPNVSISQPGKPEAYGSGDTFLPTAGKGTTPMPHLFAKAQEMLKSHDTKCEQIREGKVPACVQSAWKGRIPGDLAAGTLFPNIPQGQPLELQAENNPDLHQEAVSWKPMDLDQEAQAFSGVFIEHCRRPQALSEETIKKLETTLRHKYLAFLSGLQALYCMAPTKATSPTVDQSVITTMPWSVKSPQKPLSQKSPLEALCLSGLEPCTQDDKETSANIAEEFQHGAQGHGRTEKVPPERQPLLNRPYSLDTEIMERVSFYLKRKALDIKLGISLKESVFQEPTATDLESESVQEPLGSPRESTLLQGPPTLCHVPVAPDPDKVCLKQPATAVQVVFQEQNQPSSRAVPHRSARQGSQVHRNMMEAQVHYVQMGTGGEMLNLGEPFSTESQSPGKSKSGYVPTVAGKRKIPGKPKVVGDLGEGDAGLGFSLVSLKTRQDGEQEKRLLHRQLQGSSLQAQTFHLEGACPHSPQESPELQFADPPPEVFMETDSEQDMEDSQSKESIVPEPARTAKAPQPMLSRASQGLPFPRSPTQRKPSQGQPGPGHVPPGHATPASPYTRPSRLPEAGLKNKMKLFFHSIKLKMKSKAHTEPSTVSTPGKVAKTSKENIDRGLPQAKSPTKKTKPEDFRGPKAQFSVVGPCLTPSYILDSKFWPRPRRVGSVSVLGHSYHCPRHCPRLAYANQQRNPP", "length": 1308 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "C0HKD2-1", "protein_name": "Spermatogenesis-associated protein 31F1C", "gene_name": "Spata31f1c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSTMCFLWDTECPLYVYFCFFIIVLIVWQVRQNYQGLKCENRRSCCRRHQKVRQRAKDAASRARRLSREEDEKPCELLSIMKSQSWVPKQGNVRQLLCLDPSCQICEATTLEIRQLLQSKKSQISPALLGLPQRAACLEMPISSESFEWNQDFYSRYSTNSPVVPGNQTLTQLTEELTESTNADGVLLCWTDPLQIGQEFHLADMPMASETLVSPGLEEPVVLMNEEDTVHSNLNYIQQLQDHEALNSQIPFQTLTPQLTVTHPMAVSIVTDAPQPFLSPEVLRLLEIHVKKLMHFQRWGLPRRVEESLKQFMPNPPVYLPPEHNQPVSFILNTSSQDCVHRFEGISPETWYSYMDGQPIQTFWVSEWSSGDQGQRLSCKPIPSPVEKPLLTPDYELLHDLCLSPEGQVDGSQSNLQKKFTQLFCGLPSMHSESLGSTFLCTQGVSKNTLKPPYKEPHFLKVSPPIPLPEAAPPPSSTSPNESLDEPQRAQIGGVPFLTLSECKTLEWHLLQRQLQLQWGLPAVIARPPRVQSHTQYKHKPWNKAKPRETLKFFGPGKPFSALTRELFFIPQHARRLLEFHLQKRLIHLRWGLPQRIQRSINMLLSSTDLQSLPCGGSRLPNVSISQPGKPEAYGSGDTFLPTAGKGTTPMPHLFAKAQEMLKSHDTKCEQIREGKVPACVQSAWKGRIPGDLAAGTLFPNIPQGQPLELQAENNPDLHQEAVSWKPMDLDQEAQAFSGVFIEHCRRPQALSEETIKKLETTLRHKYLAFLSGLQALYCMAPTKATSPTVDQSVITTMPWSVKSPQKPLSQKSPLEALCLSGLEPCTQDDKETSANIAEEFQHGAQGHGRTEKVPPERQPLLNRPYSLDTEIMERVSFYLKRKALDIKLGISLKESVFQEPTATDLESESVQEPLGSPRESTLLQGPPTLCHVPVAPDPDKVCLKQPATAVQVVFQEQNQPSSRAVPHRSARQGSQVHRNMMEAQVHYVQMGTGGEMLNLGEPFSTESQSPGKSKSGYVPTVAGKRKIPGKPKVVGDLGEGDAGLGFSLVSLKTRQDGEQEKRLLHRQLQGSSLQAQTFHLEGACPHSPQESPELQFADPPPEVFMETDSEQDMEDSQSKESIVPEPARTAKAPQPMLSRASQGLPFPRSPTQRKPSQGQPGPGHVPPGHATPASPYTRPSRLPEAGLKNKMKLFFHSIKLKMKSKAHTEPSTVSTPGKVAKTSKENIDRGLPQAKSPTKKTKPEDFRGPKAQFSVVGPCLTPSYILDSKFWPRPRRVGSVSVLGHSYHCPRHCPRLAYANQQRNPP", "length": 1308 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "C0HKD3-1", "protein_name": "Spermatogenesis-associated protein 31F1D", "gene_name": "Spata31f1d", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSTMCFLWDTECPLYVYFCFFIIVLIVWQVRQNYQGLKCENRRSCCRRHQKVRQRAKDAASRARRLSREEDEKPCELLSIMKSQSWVPKQGNVRQLLCLDPSCQICEATTLEIRQLLQSKKSQISPALLGLPQRAACLEMPISSESFEWNQDFYSRYSTNSPVVPGNQTLTQLTEELTESTNADGVLLCWTDPLQIGQEFHLADMPMASETLVSPGLEEPVVLMNEEDTVHSNLNYIQQLQDHEALNSQIPFQTLTPQLTVTHPMAVSIVTDAPQPFLSPEVLRLLEIHVKKLMHFQRWGLPRRVEESLKQFMPNPPVYLPPEHNQPVSFILNTSSQDCVHRFEGISPETWYSYMDGQPIQTFWVSEWSSGDQGQRLSCKPIPSPVEKPLLTPDYELLHDLCLSPEGQVDGSQSNLQKKFTQLFCGLPSMHSESLGSTFLCTQGVSKNTLKPPYKEPHFLKVSPPIPLPEAAPPPSSTSPNESLDEPQRAQIGGVPFLTLSECKTLEWHLLQRQLQLQWGLPAVIARPPRVQSHTQYKHKPWNKAKPRETLKFFGPGKPFSALTRELFFIPQHARRLLEFHLQKRLIHLRWGLPQRIQRSINMLLSSTDLQSLPCGGSRLPNVSISQPGKPEAYGSGDTFLPTAGKGTTPMPHLFAKAQEMLKSHDTKCEQIREGKVPACVQSAWKGRIPGDLAAGTLFPNIPQGQPLELQAENNPDLHQEAVSWKPMDLDQEAQAFSGVFIEHCRRPQALSEETIKKLETTLRHKYLAFLSGLQALYCMAPTKATSPTVDQSVITTMPWSVKSPQKPLSQKSPLEALCLSGLEPCTQDDKETSANIAEEFQHGAQGHGRTEKVPPERQPLLNRPYSLDTEIMERVSFYLKRKALDIKLGISLKESVFQEPTATDLESESVQEPLGSPRESTLLQGPPTLCHVPVAPDPDKVCLKQPATAVQVVFQEQNQPSSRAVPHRSARQGSQVHRNMMEAQVHYVQMGTGGEMLNLGEPFSTESQSPGKSKSGYVPTVAGKRKIPGKPKVVGDLGEGDAGLGFSLVSLKTRQDGEQEKRLLHRQLQGSSLQAQTFHLEGACPHSPQESPELQFADPPPEVFMETDSEQDMEDSQSKESIVPEPARTAKAPQPMLSRASQGLPFPRSPTQRKPSQGQPGPGHVPPGHATPASPYTRPSRLPEAGLKNKMKLFFHSIKLKMKSKAHTEPSTVSTPGKVAKTSKENIDRGLPQAKSPTKKTKPEDFRGPKAQFSVVGPCLTPSYILDSKFWPRPRRVGSVSVLGHSYHCPRHCPRLAYANQQRNPP", "length": 1308 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "C0HLM6-1", "protein_name": "Small integral membrane protein 20", "gene_name": "Smim20", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAARNLRTALIFGGFISMVGAAFYPIYFRPLLRLEEYQKEQAVNRAGIVQEDVQPPGLKVWSDPFGRK", "length": 69 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "C7G009-1", "protein_name": "Thioredoxin fold domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNLILNGNWLVKFGAGWSGHCKKLQPVLENLAQHYNSDNENSKVKVAQVHCEEYESICIKYNIIGYPSLVFFDEGEIKHYRGPRLFENFKEAIDKHLNKEFVAFSQNQPSKIIVITNENLDLLLTGNWLVKFGAAWSLHCKKLQPVLENLAQHYNSDNENSKVKVAQVHCEEDNSICKKYNITGYPSLVFFNEGQIKHYTGPRQFENFKEAIDKHFKYGVKWSGHCKKFQPVLENLAQHYNSDIENSKIKVAQVHCEGDDSICKKYNITGYPSLVFFDEGETKPYRGLREFDKIKEATDKHFK", "length": 303 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "C7G010-1", "protein_name": "Calcineurin-like phosphoesterase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKLKIKFSIISLFILKLVISKPILKFNNNNQFKIIQFTDLHYGSEPVDDIDTIFSQVNILDYEKPDLVILSGDMVTGYEEQFEDDDRNYWKYWNVFTRPFVERNIPWAITFGNHDGEGALSTNEILKIDQTFNLSLSQSNPVEMHGIANYVLKISSSNSLKSEPASLVYIFDSSTKGCSKLDWGCVHQDQVDWFKNTSKSFNKTDSIAFVHIPPVEIIDLWNNYPVYGNYSETSCCFDNDYGDFVSSLVESGDVHGLYFGHDHENDFHGDYKGVDLGYGRKSGAGSYSSKKPLGARVFQLTESPFTLSTWIREEDGNIVSQVIHPPSEFDRKPLQCKMKDKYSKKELIAIKVIGGFLIFLGIVVVGLIGFFGFKHYKKFKKQTLEMQNLV", "length": 390 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "C7G064-1", "protein_name": "SET domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKKDEKQFQQFPNKGRTVQANTDLPKGSTVFRCAPFASSIEDSDKLATEKYCGFCLQRIPKSDSKECLCKNCKLYSVCKSCRSINESAVEPFQIIIKSTFHLGSDTRDMRLLLRIIANIANGKQGMQTPIDDYQDFMGLTSTLDKVDKEHMTKFKRGVTSISSLISSVRGVGYLKNTITIHEILECFSSVLTNAHQFSYATSKEIGRGVCPTGYFNHSCMPNTTWSLDDQGMLLFSTSSNVKKGDELSLGYLANEYPLKNRRRELLDGYYFFCQCPLCEFQSNLSGYLCEKCKEPLLNDSIVYHEPSLTNPLDTGIGLIKHLRKMIDFRQQSVEFKKMFSSEQLSNILQKGVPKHIQSVFNCDASDNEELQQIVEISERSIKSLPLINGEPIDFYPLSDRNYYEYFKQLKNSKISSPEELQRIKDKILSLINPTIYNSFKDKIDKRLLI", "length": 449 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "C9JPN9-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 12", "gene_name": "USP17L12", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEEDSLYLGGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSCETRVDLCDDLAPVARQLAPREKLPLSNRRPAAVGAGLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRALHNPGHVIQPSQALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKMLTLLTSAKVLILVLKRFSDVTGNKIAKNVQYPECLDMQPYMSQPNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQEGQWYKMDDAEVTASSITSVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRATQGELKRDHPCLQAPELDEHLVERATQESTLDHWKFLQEQNKTKPEFNVRKVEGTLPPDVLVIHQSKYKCGMKNHHPEQQSSLLKLSSTTPTHQESMNTGTLASLRGRARRSKGKNKHSKRALLVCQ", "length": 530 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "D3YTW8-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r258", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVRGKSLKTTEEVALQIILLCQFGVGTMANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTVFPNNMMAFAPRNPPTELKCKLKFFSHLVTRSTNLCSTCVLSIHQFVILVPISRGKLLLRASVPNLVSYSCYGCWFFSVLSNIHIPIKVTGPQITDNNTDSKSKFFCSTSGFTVRIVFLQFSHDATFMSIMVWTSVSMVLLLHRHRQQMQHILTPNQDARGQAESRATQTILIVVVTFVSFYLLNFICIIFHTFFIHYNLFIRLLGEILAAGFPTISPLLLIFRDPKNPCLELFHCFKPESLQNL", "length": 314 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3YTX5-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r259", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQLLLLCQFGVGTLANVFLFVHNFSPVLTGSKQRPRQVILSHMAMANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVLVNRGKLILRASVPNFVSYSCYSCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVFLQFAYDATFMSIMVWTSVSMILLLHRHRQRMQHILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNFICIIFHTLLMHSHLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFNC", "length": 305 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3YTY1-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r107", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMSAFAPKTPPNELKCKLDFFSHMVARSKNLCSTCVLSIHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLQFSHDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3YTY2-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r138", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVHDKSVKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGYKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPNELKCKLESFSRLVARSTNLCSTCVLSIHQFVTLFPLSRGKGKLILRASVQNLASYSCYSCWFFSVLSNIHIPIRVTGPQITDNNTDSKSNLFCSTSGFIVGIVLQFAHDATFMSIMIWTSVSMILLLHRHCQRMQDILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNCICIIFHAFFIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 306 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3YXI8-1", "protein_name": "Predicted gene 10377", "gene_name": "Gm10376", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGSQAGSFRKASPQTPNIDENEKRIKRLEKLKRDLQNIKNERDILQGILAKYKDLNDRTNFETFMLEMQNNQMMTDLKRMSQDISEALYKCQHLTKENQLYCCRNCHLLIESNLIQHKVRMLWKENRQLLRKQIALEECNIKTKILCKEGSQKIKDEYSRQAAGKQIIVVPGSKEEAVMSNPCA", "length": 184 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3YYI9-1", "protein_name": "Predicted gene 7347", "gene_name": "Gm7347", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRVNVDGRETREGRKDADLPSERNEGRRRWTWRMCMAHRQTTSPVPVKSKKQFEKEEKELIKKIQLTTKETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTFLHDLEMKNMEARENNQELKKEKNFYRNLHTRILLGENLIKKKLAILQQESKEIHADWAIIQQRLVELNLSGKDEQEKTSNLEAQENQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPSSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3YYY1-1", "protein_name": "Secretoglobin, family 2B, member 7", "gene_name": "Scgb2b7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLGLLVTGELSFQTTEACFPFFEAYASVLSGSRVWLYQELQAFDATAEEKVALEKIQDCYSEESIRNILLEPKIMEAMVASPECLSYYGLDNIRSILDYISKLLGE", "length": 112 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3Z236-1", "protein_name": "Predicted gene 3676", "gene_name": "Gm3676", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGSQTVSFRKASPQTPNIDENEKRIKRLEKLKRDLQNIKNERDILQGILAKYKDLNDRTNFETFMLEMQHNQMMTDLKRMSQDISEALYKCQHLTKENQLYCCRNCHLLIESNLIQHKVRMLWKENRQLLRKQIALEECNIKTKTLCKEGSQKIKDEYSRQAAGKQIIVVPGSKEEAAMSNPCA", "length": 184 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3Z8D1-1", "protein_name": "SIGLEC family like 1", "gene_name": "Siglecl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLWGLRSLLLLHLGFLSPVLVDTKKTAVEDGLCSTVPCVIEFSKAPLRKPMIVSYRLNENISFHAGTSQPRGPVADLSTEEVEYCILLTHNMLGRKNMTYSLYVGLGAQKDLTQKQELHIPGSSMAGEPVSLTCTIHSTCQESKALFLSWKGPIMSSSTTVPINPSSALAIDPKPEDQDTTLRCHLKLSLDNLSSSKVVKLQLVSPARLLNYSCLLKRTLTCSCSFHGIPTPSVQWWVGRTPVSVNSIDAILHMTSTTLESWTNSTIHLMWEPEIIKSLRCEGKNQYGVHASGIFLIPDKSSVSSVFLRGLIQGIVYGAIASALFFFFLVVLGMKILNWWEENQTCKNEEAPTLKKPVWGGAKPAEVGS", "length": 369 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3Z8T0-1", "protein_name": "High mobility group nucleosomal binding domain 2, pseudo 3", "gene_name": "AABR07053402.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPKRKAERDAQGDEAKAKDEPQRRSARLSAKPAPSKPKKAPAKKREKIPKRKERKADAGKDANNPAENRDAKTGQAQKAEGAGVAK", "length": 86 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3Z9U8-1", "protein_name": "S100 calcium binding protein A7 like 2", "gene_name": "S100a7l2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAQNLTSSEQEVMKLFDLFQNYHVRRTDKLDVQETKRVLREFFPNFMKALNASGIKILNDLEKEITLDEIWDMIGRMAMAYNKKNSNALKD", "length": 91 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZAM9-1", "protein_name": "Olfactory receptor", "gene_name": "Or4f60b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKKVNYSVTSEFVFLGFTNSWDIQLLLFLVSSMFYVACIMGNCLIIFTVASDTHLHSPMYFLLANLSFIDVGISSATSPKMISDLLKKHKVISFRGCVIQIFFNQAIGGAEMVLLIAMAFDRYVAICKPLHYLTMMSPQMCLFFLITAWVVGLMHSVIQLIFIVNLPLCGPNILDSFFCDLPQFIKLACMNTYRLELLVSISSGFMSLVSFFLLSISYIVIILTVLKHSSSGAYKALSTLSAHVTVVVLFFGPAIFFYIWPSSTHLDKFLVLFDAVVTPFLNPVIYTLRNKEMKRAMRRVFRHLMGYRQIS", "length": 311 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZC26-1", "protein_name": "Ferritin", "gene_name": "Fthl17fl", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAEASSQVRQNYDRCCEDAINNHIRLLLQASYSYLSMAFYFDRDDVALGNFKRFFLSKSHNCKASAEMFVFMQNKRGGHVFLPSIAKPDRESWHGGLRAMECAFRMEMTINQSLLNMHELAKGKDDAHLCDFLGQHCLDQQVHVLKKMGGYLTNLRQMGAPEQGLAEYLFDKLSLS", "length": 176 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZCM9-1", "protein_name": "Dynein axonemal assembly factor 3", "gene_name": "Dnaaf3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTTPAGSGNGFGTVSWWGLSPALDLQAESPPVDPDSQSKTEHKIPELDALLLGSVDGRHMLRTLARAMLWPLRRFNFYVLENNLEAVARHMLIFSLALEEPEKMGLQERSETFLELWGNALLRPSVAAFLRAQASHLSNLVPEPDRLEELLPWLSLRPLKFRERDALEAVFRFWSGGEKGPEVFPMSRLWDSRLRHYLGSRYDARRGVADWDLRMKLHDRGAQVIHFHEFRRWRDTGVAFELRDLSAYHVPNRTMASGRLLSHRGERVAARGYWGDIATGPFVAFGIEADDKSLLRTSNGQPVKTASEITQHNVTELFRDVAAWRGPRAIKGNVEETKSPEPDAPAQEPFTIHFLPLDSSQTLHHKTCYRGRFQLLYVSCGMIHLLSPELGACVAPGGNLVVELARYLVDLRPKELKAFSDRVVEIAQAAGFAPHTGTKPSETFARFYKLGDSTRGGGDSAVESGPVPSKVLAPTPESINPPQADQAPSLEVMSPPKVDQTPPLEAMSPPEADQAPPLEAMSPPRADQIPPLEAMSPLQAEVVLPLEAISPPQADLAPPPEVISPVQEALAMSSAIAPLKHVT", "length": 583 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZCW3-1", "protein_name": "SPATA31 subfamily E, member 1", "gene_name": "Spata31e1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "METFLLLMNSISDFWMSSSSMSTVMDMIFAILCGVGFFFLLIPFLKEYPGSPPPGSKKNISEVVKRRQSKDRKKSVTVDGCRDSQKNSLDIQHDLQTMESPIQHLLLDSSPHPFWNSKEKLNQLSLPQLFSYLKVLEALIQQKFNQLLLGLSSVLSESVVATAWVSREPSSGERKTVRFSDSLGFDQALPLAKGPPQRCLDQPLPHQLVTPSLVGMTEIQEQENLPNSISYQTPSIFQSRARGTAYPTTATGIQVPLPTTNEPCHPGLNWKDIPSCKVQNCQGASSQPTESLARCTLPTKNTRSASIPPEHYLMVHHHEQPQHEEKAINLGEQQRTHARFLPSKEPAQLQGDSPPNSNGYGKNWPELNQPAQPSTLNSKTYKWNQMMGPVPTGMLLKKVIAKYGIPNTIKKDLKLRVKDLLCTSSSTPGESLETKNLTLRTDEHSMNTTENLSFLDPKTTMMKSNIMQLPMKHRQLPCDSKAEPYTKAAFILENLHHQDPGGIRVETASSARLRSPLFEQSPPEVQKTQSSPPPIDSHGHSRSHPDQWQRYQSVQPHALCSQAQPQQSRSIQGTGRSILQPNISVWMSKHERWMRSEDVASGHTSWSSRTVGYRDRVSPSVAKQTNILKIKEESPHVWRANLGSGEITNEQALNNSNEDFEPIEAKRSQGHLQMPTQQNTGYLHLKTEEYSNNDLKVNKQPQAWSVSHHADGSNTVHHAMVKLPSQHSLPSLQNGWQDPKTSQGLGDLLMNRDQSVETQFRVHKDKTEATNDSVFHPSEKRPSNLKYGGISQGERLGRVKSSISSFTQLKDSAKTESKSSPNIGGKREAPSKSSLKFIWNGAQYENLSTKLKGQRDSLKKDIPPPVTEQTQEVVHRINVIYSTAVELQSLMDSLVHKLVKTVGEPSELTRKHMTKVQEYKMESLPFQLGSSSQPSKGLHDPNKSRSVRRMSDDHTSPKEPNNHTFTYRGNRDKMQAGVDVQRVCYQHLDKVKIGFGQHSTPMRNGNPCFHKKAGDKQESSLADQSTGDADQTKPKNEIVGSPHRIPERHNQSSRYREIRDNQEPSVDHKAIDPHQNTKKGMGYSQLMSPKENHPVKISGTAAQGASDPEEIRTKSGKECSPHRSPKMHDHSLRHREVRDKPQPGINTQRAYDQHLNSPKKRMTSENLLTPKGTNHPCWHRVTGDKQQSSLSDQRACDPEQMRRSGMSSYPQRSPKVYHLSCSSEKIGEKLLPLVNDQRTHDKHPNSVKTRGCDNLPTPKGSNHPQGYRVIEDKQQLGLAYRRTCDPGQIKKSGMGKGPCKDTEECNLLYRYKIIGNKQQPGIVHRACDRHQSSKEGMGQGQPMNPKVCHSAKHRRTGGQDQSGVAAQGASNPR", "length": 1373 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZDD6-1", "protein_name": "Synaptonemal complex central element protein 3", "gene_name": "Syce3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MADSDPGERSYDNMLKMLSDLNKDLERLLEEMEKISVQATWMAYDMVVMRTNPTLAESMRRLEDAFLNCKEEMEKNWQELLTETKRKQ", "length": 88 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZDJ1-1", "protein_name": "Olfactory receptor", "gene_name": "Or13c3f", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDDMDKNNQTFVSEFLLLGLSGYPKTEILYFVIVLVMYLVILTGNGVLIIASIFDSHLHTPMYFFLGNLSFLDICYTTSSVPSTLVSLISKKRNISFSGCTVQMFVGFAMGSTECLLLGMMAFDRYVAICNPLRYSVIMSKEVYVSMASASWFSGGINSVVQTSLAMRLPFCGNNVINHFTCEVLAVLKLACADISLNIVTMVISNMAFLVLPLLLIFFSYVFILYTILRMNSASGRRKAFSTCSAHLTVVVIFYGTIFSMYAKPKSQDLTGKDKFQTSDKIISLFYGVVTPMLNPIIYSLRNKDVKAAVKYILKQKYIP", "length": 320 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZDT4-1", "protein_name": "Transmembrane protein 92-like", "gene_name": "LOC100364194", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQEAWVLDALTVIFGLLFSLQGVSSNKTIYKCEDIHCPKGFRCCDNECCLERKIWNTDNEPFRILFIILLVMLPLLCICGLVRRFCPKCRELQHEVRTADHQSPPDPPSIAPLESIWVTSLDPPPPYSQVVQKSTPTEPPPPYSLRPEDSTCPMRETSHETL", "length": 162 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZFJ9-1", "protein_name": "Family with sequence similarity 24 member B", "gene_name": "Fam24b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFSSFDLRTIIMIVIGSGILAAMFLLTGVVLCLYSKIARALNPSGTGKELDDQLCSDPCKTTQDQIIRVNSLNADTCRPFHGSTIGLENCQPLQCFSACGTYEGANSLTPCLCNTKEGL", "length": 119 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZFW5-1", "protein_name": "Transmembrane protein 107", "gene_name": "Tmem107", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGRISGLVPSRFLTLLAHLVIVITLFWSRESNIQACLPLKFTPEEYEKQDNQLVAALCLTLGLFAVELAGFLSGVSMFNSTQSLLSIAAHCSASVALSFFIFERWECTTYWYIFAFCSAFPAVTETALFIAVFGLKKKPF", "length": 140 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZG05-1", "protein_name": "40S ribosomal protein S12", "gene_name": "LOC120100003", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAEEGIAAGGVMDINTALQEVPKTALIHDGLARGICEAAKALDKRQGHLCVLASNYDEPMYVKLVAALCAEHQINLIKVDDNKKLGEWVGLCKIDREGKPRKVVGCSCVVVKDYGKESQAKDVIEEYFEYKK", "length": 132 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZGM7-1", "protein_name": "Peptidase inhibitor 16", "gene_name": "Pi16", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRNCRVSWMPQHSSAAVSGICPPQEGPWSSYSLWPEPPLLREKEAVAKDSRGVDSTLVQTQGTQPSWRHCVSWAGPPDTAPAAPPQPGWCLCGKDFKSSRQTPDRERQRGLATMHSSCSPWVMLPQLPLLLLLLLLLLTATGPATALTEDEKQTMVELHNHYRAQVSPPASDMLQMRWDDELAAFAKAYAQKCVWGHNKERGRRGENLFAITDEGMDVPLAVGNWHEEHEYYNLSTATCDPGQMCGHYTQVVWSKTERIGCGSHFCETLQGVEEANIHLLVCNYEPPGNVKGRKPYQEGTPCSQCPLGYSCVNSLCEPERKPEKAQDSPPRVTEVPGSRETGIPSLATSESLHFSSVTKVSDSLATEPSPAVETKAPPSLATEGPSSMATEAQSFLTEVPSVSATHIQPSLDEGPVNFLTSTHIPVPKSTDKEASSKSRAASVSPEKSLYPKMSPTETGESPPQIQEEAEPKAELPEREDELPEAEVELPEAEAELPEAKAELPVSSEALVPVLPAQERGGPKASLEHSSYPVPTYLPNFPSASGNATGGRTLALQSSRTGAEDPEKASWDSKNSAPVWGPFPGLLLPLLLLAGIF", "length": 596 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZGX2-1", "protein_name": "C-type lectin domain family 2, member M", "gene_name": "Clec2m", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQTESSLRLSQSSHHRLTFDLKKVVTLWILVIGVIAVLLWGFFSFPKKFTVTRQTKNEVCSDGVKICLHGWNKLNRNCFTHFSHANSWFTAKETCKFHDATLAVFNDQTELDIVMKQMEDIQTFWIGLYKKDFRGPWVWTNGSKYNNWYEVQDYGHCAFLHKSGIDSTNCNDLKEYICTQEGHCP", "length": 185 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZIZ8-1", "protein_name": "Ferritin", "gene_name": "RGD1560203", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAEASSQVRQNYDRCCEEAVNTHIRLLLQASYSYLSMAFYFDRDDVALENFKRFFLSKSHDCKASVEMFVFMQNKRGGHVFLPSIAKPDRKSWQGGFRAMECAFRMEMTINQSLLNLHELAKGKGDAHLCNFLGQHCLDQQVHVLKKIGGYLTNLRQMGAPEQALAEYLFDKLSLS", "length": 176 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZKK4-1", "protein_name": "Zinc finger protein 869", "gene_name": "Zfp869", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDTPIVGLSSPDQGLVSFEDLVVHFTQDEWDLLEASQKSLYGDVMLETFRNLTAVGYEWEDEAIEDHCEEPEVNLRDIVSHSEYTHEYEHKEYEEKPPDANFLTSVEGCVETKTSSGPSVCEVCLKTFGLYHLTYNGHHNYDYKELRGSQTEENDCEGNSCDKTSGSLQKEDKIHTGKKLYVCQECGKAFRYPSALQLHERIHTGEKPYECKDCGKAFRGLSALHLHERIHTGEKPYECKQCGRAFTYLSALQLHERIHTEERPCECKQCGKTFRYSRALKLHERIHTGEKPYECKQCGKFFRSHRTLKLHKRIHTGEKPYECKECGKAFRWLTSLKLHEKIHTGEKPYECQECGKAFRCQASYHRHKITHGGETLYECKECGKSFIYPSLLQVHERTHTGEKPFECKLCGKAFRCQSSLRLHERTHTGEKPYECKHCGKAFSSYNYLRFHERSHTGEKPYECKECGKTFTHRSYLRSHERRHTGEKPYQCIQCGRSFSRHSSFKRHQSVHGESPYEQYLIPLSPFSSKE", "length": 530 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZKM3-1", "protein_name": "Protein GPR15LG", "gene_name": "Gpr15lg", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRLLTLSGLFFMLFLCLCVLSSEGRKRPAKFPKLRPCCHLSPRSKPITWKGNHTRPCRPCRKLESNSWVVPGALPQI", "length": 77 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZL22-1", "protein_name": "Olfactory receptor", "gene_name": "Or1x2b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSKWGENETGVIEFLLLGITNDPQQQRILFWAFLCMYLVTVAGNTLIFLAISSDPHLHTPMYFFLANLSFDDVCFTTNIIPRLLAGHVSGTETISYAYCLTQMYFLISFGNVDTFLLAAMALDRFVAICYPLQYHTIITPRLCVGLASVVWISSGLIALVHTLLMSRLTFCSSIPEISHFYCDAYLLMKLACSDTRINQLVFLGAVVFFVAPCILIVFSYVRIAMAVFQIPSAKGRHKAFSTCSSHLTVVILFYGTVLGIYIRPPDSFSTQDTVATIMFTVVTPMLNPFIYSLRNKDMKETVTRLLHRGSKSS", "length": 313 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZLG9-1", "protein_name": "N-terminal Ras-GEF domain-containing protein", "gene_name": "AABR07047293.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFSCCVWTTEGSGLKKDKNEGQGGTWKFMLLSCLQCLWPFAQKEIDLTRDNQAQDHEDQGEHEYAPQVVTEPCRESRISADMVENLVNRLVSSLQGGDPFFIPAFLYGYRQFTTTQHVLDRLLKRFAYFYLGCEEDEQIKSSLCCFLDTWIDQYPEEFSQTILKKLKTYLTVNMPSSDLNLRVHMLLKELRQESNESEGKDDDSVSLPVTLLYKTASAADLSSSVEVGSHTSGDLDIEVWFPSQKVQPEPAYPHETETPQSTIKVISWD", "length": 269 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZMT2-1", "protein_name": "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3", "gene_name": "Ndufa3-ps1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGRSSDFFKNAQAKEPVLVVSFSVWGLAVILPMISPYIKYAGVISKATPYNCPVPVRDNGNVPGVPSQPQERLSPSLERLKNL", "length": 84 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZNA3-1", "protein_name": "60S ribosomal protein L7a", "gene_name": "AABR07049918.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPKGKKAKGKKVAPAPAVVKKQETKNVVNPLFEKRSKNFGIGQDIQPKRDLTRFVKWPHYIRLQWQRAILYKQVKVPPAINQFLQALVRQTVTQLLKLAHKYRPETKQEKKQRLLAHAEKKAAGKGDVPTERPPVLRAGVNTVTTLVENKKAQLVVTAHDVDPIELVVFLPALCRKMGVPYCIIRGKARLGRLVHRKTCTTVAFTQVNSKDKGALAKLVEAIRTNYDDRYDEIRCHWGGNVLGPKSVARIAKLEKVKAKEFATKLG", "length": 266 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZNR1-1", "protein_name": "Elongin-B", "gene_name": "Elobl9", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEVFLMIRRKKTTIFIEAQELTTVLELKRIVQGILKRPPEEQLLFKDDQLLDESKTLRDCGFTSRVAKAQDPATVGLVFREDASEGLQIHPYSTPLLPSVMKTGTDSLE", "length": 109 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZNU6-1", "protein_name": "Olfactory receptor", "gene_name": "Or5p66b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSWLENGNHTTVAEFLLLGLTDDPVLRVILFTIILCIYLVTVSGNLSTILLIRVSSQLHHPMYFFLSHLASVDIGYSSSVTPNMLVNFLVERNIISYLGCGIQLSLVAFFGAAECFLLAAMAYDRFMAICNPLLYSTKMSTQVCILLVVASYIGGFLNASFAMVSFCSFLFCGPNIINHFFCDFAPLIELSCSDVSVYVIATSFSAGSVTMITALVIAISYSYILITILKMHSTEGRQKAFSTCTSHLTAVTLFYGTVTFIYVMPKSSFSIDQNKIVSVFYLLVIPMLNPLIYSLRNNEIKSALKKQIWRKTVS", "length": 314 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZPU6-1", "protein_name": "Large ribosomal subunit protein eL21", "gene_name": "LOC134485591", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTNTKGKRRSTRYMFSRPFRKHGVVPLATYMRIYKKGDIVDIKGMGTVQKGMPHKCYHGKTGRVYNVTQHAEGIIVNKQVKGKILTKRINVRIEHIKHSKSRDSFLKRVKENDQKEKEAKEKGTWVPLKRQPAPPREAHFVRTNGKEPERLEPSPYGFMA", "length": 160 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZQ96-1", "protein_name": "Large ribosomal subunit protein eL21", "gene_name": "LOC102550668", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTNTKVKRRGTRYVFSRPFRKHGVVPLVTYMRLYKKGDIVDIKGMGAAQKGMTHKCYHGKTVRVYNVTQHAVGIIVNKQVKGKILAKRINVWIEHIKHSKSRDSFLKQVKENDQKKEEAKEKGTWVQLSLQPAPPREAHFVRTNGKEPELLEPVP", "length": 155 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZQD9-1", "protein_name": "Developmental pluripotency-associated protein 3-like", "gene_name": "LOC120096627", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDKSSEKVDPVVNPETQMNDGSQREDEEDSPDDSEILQPETLVKVMKKLTLNPSAKPPKYHRHQRVRLRIKSQPVGNRSERIMREVQSAFPKTRVRTLLSVLKDPIARMRRFVRIEQRQRQLEGNERRDEPFRCLCTFCHYQRWDPSENAKIGQNQKN", "length": 158 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZQT0-1", "protein_name": "Glyceraldehyde-3-phosphate dehydrogenase", "gene_name": "AABR07071101.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MILCIKPSSTTKYCLNQCYLISCINKPNLLDGVNGIPLDIVAINDPFIDLNYVVYMFQYDSTHGKFNGTVKAENGKLVINGKPTTIFQERDLANIKWGDADAKYVMESTGIFTTMEKAGAHLKGGTKMVIISAPLADAPILKYDNSLKIVSNASYTTNCLAPLTKVIHDNFGIVEGLMTTVHTITATQKIVDGPSGKLWRGGHGAAQNINPETTGVAKAVGKVIPELNGKLTGIAFHVLTPNVSVVDLTCHLKKPAKYDDIKKVVKQASKGPLKGILGYTEDQVVSCDFNSNSHSSTFDARTGIALNDNFVKLISWCDNEYGYSNRVVDLMAYMASKE", "length": 338 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZTK7-1", "protein_name": "Uncharacterized protein", "gene_name": "AABR07012426.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSGDLEAKISGYTHISVQRFCYKWTISNFSFCMDGIRENITSPVFSLEGNEEVQWCLRIFPNGVDEESKDYLSVSLGLHSCPKSPVLAKVQFWIINAQGEKHQIKEIPNILSFSPKHQWGLRKFILREFLLSRRHGLLPEDQLILCCKVSVVGPSFSTPGHNMTPANKDPRQMLADDVGELWENSLFTDCSLVVAGQEFRAHKAILAARSPVFRAMFEHEMLESLTNRIEIHDIHLQVFKEMMAFIYTGKAPHLHSHSMATELLAAADMYDLQDLKVMCEDSLCRNLSVKTAVPTLMADLHSTELLKTRVMDFIILHASEVSETLEWKSMVESHPHLVEEAFGSLASMHYFFLEPSLKR", "length": 359 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZV50-1", "protein_name": "Small ribosomal subunit protein uS4", "gene_name": "Rps9l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLVARSWVCHKTYVTPRRPFEKSRLDQELKLIGEYGLRNKHEVWRVKFTLAKIRKAARELLTLDEKDPRRLFEGNALLRRLVRIVVLDEGKMKLDYILGLKIEDFLERRLQTQVFKLRLAKSIHHAHVLIRQRHIRVRKQVVNIPSFIVCLDSHKHIDFSLRSPYGGGRPGRVKRKNAKKGQGGAGAGDDEKKEK", "length": 195 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZWL0-1", "protein_name": "Ribosomal protein L32 like 1", "gene_name": "Rpl32l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAALQPLVKLKIVKKRTKKFIRHQSDRYVKIKRNWRKPRGIDNRVRRRFKGQILKPNIGYGSNKKTKHMLPSGFRKFLVHNVKELEVLLMCNKSYCAEIAHNVSSKNRKAIVERAAQLAIRVTNLNARLRSAENE", "length": 135 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4A176-1", "protein_name": "Golgi associated RAB2 interactor 5A", "gene_name": "Garin5a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPRLRTSARSPAPAVRMAISPSGPLGFTSPVTQPRREASPGVPTTQGRGVAMKGGRDLKPASGRADRPLAQAYAPCRPGRLQRHLLSGEFDQLRDFPIFESNFVQVTRFGEVANKVTMGVAASSPALELPDLLLLAGPDKENGHLQLLGLFPLQFVQLFVHDVSRQQLKVKFRTGRAFYLQLRAPPETRDCEFGRWVRLLYRLRFHSPTCAVPFTHEDTVPEESEDEDEVEEGQLQPPEVRAGPRAQGCWARKDGKGPVSCHRGQTRPAGLRTLGALIQPRSFQITKGPEIKPAQLRAREMDF", "length": 303 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4A9N2-1", "protein_name": "Olfactory receptor", "gene_name": "Or4a77d", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGQNNSVSEFILLGLTEDPAGQKTLFVVFLLIYIGTMVGNLLIVWTVIASPSLDSPMYFFLAYLSLIDALYSSTILPKLLIDLLCDKKTISLTACLVQLFVEHLFGGVEIFLLVFMAYDRYVAICKPLYYLTIMNQRVCVCLVVVSWIGAFAHALVQVFSVYKLPFCGPNIIDHFACDMYPLLGLACTDTYFLGLTVVGNNGAISVVVFMLLLLSYGIILNSLKTHSQEGRRKALSTCSSHIMVIVLFFVPCIFMYVRPVSNFPLDKFITVFYTVFTPMLNPLIYTLRNLEIKKSMEKLCRKIFTSDRIRISSCYS", "length": 316 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4AAM5-1", "protein_name": "Preferentially expressed antigen in melanoma-like", "gene_name": "Pramel", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDVKTPNKLLELAIHSLLNEESAAIQALEEIPRELFVPLFIAAFEGGHKNVLSAMVKVWPYYCLHIGSLSIQEPQHELLKAMIENLPVYPAPSSSSRGPKLRILDLRQDTDCRITCPEVSTKTPSCFYSCAYSDRSITKIERQLCCVNAECKTLLPRPVELLVDLSLDGSLMEKEFLVLLMYKIEESLGSLHVCCRDLQIDKLCKCKCTLKFLDLKCIDQLSVDRGSLSDITSILCRMIHLESLSLSNVTFRSLSGKVFKIFLSHLQRMEHLKELSLSSFCLKNHLDRVLRILPPGLDFLYLPFCDLSYRDFKFMSQSPQVTHLKLLNLSNNPMYWGDFEPFHTVLINLSGTLQHLEINHCLISDSAMSALIPALIRCTRLRVLGFASNPISMPMLVNIMHNLTPMKELKYVIYPIPVHCYERWHFQGSLDRQKLAIVQLQLKAMLELAHREDMNWITYCE", "length": 461 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4AAN9-1", "protein_name": "Similar to human chromosome 6 open reading frame 52", "gene_name": "C17h6orf52", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVETQSPGKECAVLPLWVLTVTSCPLPSAIREQLRVHHSLRCHRDNHYELLHSFYWLSCYSRGSTLSGNGLGPLCVTENPELLAGPWAIPEETTDPAENQEEDFLRDPNLHLNIEESDKEFMAVREELYDSLMNRRWHCLDTVLSNVPDELPQCEVF", "length": 157 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4ABB6-1", "protein_name": "Olfactory receptor", "gene_name": "Or13a27c", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "VNCIWHSKMVSPNQTVVTEFVLQGFSEHPSLRLFLTGCFMSLYTIALMGNIVIIALVTSSTGLHSPMYFFLCNLATMDIICTSSVLPKALVGLLSEENTISFKGCMTQLFFLVWSGSSELLLLTVMAYDRYVAICAPLHYSSRMSPQLCGALAMGVWSICAANASMHTGLMARLSFCGPKVITHFFCEIPPLLLLSCSPTYVNSIMTLIADAIYGGINFVLTLLSYGCIIASILRMRSAEGKRKAFSTCSSHLIVVAMYYSSVFFAYISPGSSYNPERSKFTSVLYSVLSPTLNPLIYTLRNKDVKLALGRILASFSH", "length": 318 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4ADX2-1", "protein_name": "Olfactory receptor family 4 subfamily A member 80", "gene_name": "Or4a80", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGQSKIVTEFVLLGFTQDPAGQKALFVMFSLMYIATMVGNLLIVGTVIVSPSLGSPMYFFLASLSLMDAVYSTAISPKLIVDLLREKKTISFRACISQLFIEHLFGGVDIVILVAMAYDCYVAICKPLHYLIIMNRRVCILFLVMAWAGGFAHALFQVLAVYNLPFCGPNIIDHFGCDIYPLLLLACTDTYLIGLTIIANGGAMCIVIFILLLLSYAIILRSLQNHSQEGRHKALSTCSSHITVFFLFFVPCILMYVRPVSSFPIDKSITVIYTVVTPVLNPLIYTLRNSEMKNSMEKLLQKILSPNRLRLLCCLYY", "length": 317 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4AEJ6-1", "protein_name": "Peroxisomal biogenesis factor 11 gamma", "gene_name": "Pex11g", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALLNGLASALESYRGRDRLVRGSVGPWRDRSDLEFGQDSEMRKTGQRGGPKGTDIGRLVSYMRTSYLSLPNCWPYKCVLALQIRTLGYGCQLIGGVLVEQCPSRSEVGRRLLVVSAQLSHCRTVLRLFDDLAMFVYTKQYGLGAEEEDVFIRWLSVLSNMADQLYYPCEHVAWAADAKVLQVDSARWWTLSTAFWSLSLLLGAVKSLWTMLKLRQKLRSPTGHFASQLPRSKWRAVEARIWSEALTLLSNLADLANAVHWLPPGVLWAGCFPPWLVGLMGTISSILSVYQAARAGKQAEVDSP", "length": 304 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D6R901-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 21", "gene_name": "USP17L21", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEEDSLYLGGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSCETRVDLCDDLAPVARQLAPREKLPLSNRRPAAVGAGLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRALHNPGHVIQPSQALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKMLTLLTSAKVLILVLKRFSDVTGNKIAKNVQYPECLDMQPYMSQPNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQEGQWYKMDDAEVTASSITSVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRATQGELKRDHPCLQAPELDEHLVERATQESTLDHWKFLQEQNKTKPEFNVRKVEGTLPPDVLVIHQSKYKCGMKNHHPEQQSSLLNLSSSTPTHQESMNTGTLASLRGRARRSKGKNKHSKRALLVCQ", "length": 530 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "E0CXP6-1", "protein_name": "UMAP1-MVP12 associated (UMA) domain containing 1", "gene_name": "Umad1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFHFFRKPAESKKPSGPEPEADGFVLLGATANEVRCKTSEAEGSQALETGKEDTSSVTVSGPETENQTGQTLQNNSLTAELLSDVPFTLAPHVLAAQGTISDLPDHVLSYDVGDNLSRFWYDFTLENSVLCDL", "length": 133 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E0CZF1-1", "protein_name": "PRAME like 34", "gene_name": "Pramel34", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSGQTPPTHTLLTHEALIMSSLEELPTVVFPALFKEAFAGRHTNLLKAMVAAWPFPCLPVGPLMKKPNLETLQALLDGIDMRLTREFHPRRAKLQVLDMRNMYHAFWNIRADANDSDCKSKTLDEKQLVKVLPRYARRQRLKVIVNLSISSHFNKSKAYFLNWAKQRIGSLYFCCIKMRIWDPPDQVIRDIFNVFDPEHITELELNTDWTLLQLAHFASYFGHMKNLQKVFLAPLHKNTSPIINITNATEAKCVHKIISQFSQFNCLQHIFMKHVHFLRDYMNQVLGCLMTPLETLSITQCLISQRDFDLFSCSQNLFKLKHLEIRGMILYALDLMPLRVLLEKVADTLEILDFQWCRMKDSQINALLPALSQCTQLNQINFYNNDFSMCTLKALFQHTANWSKMNVEQYPAPLQCYSELGHVSVERFVQLCQELMYTLRAIRQPKSISFATDNCQKCGKPCVYDQGPILCSCFQ", "length": 475 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E1B8K9-1", "protein_name": "40S ribosomal protein S6", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MKLNISFPATGCQKVIEVDDERKLRTFYEKRMATEVAADTLGEEWKGHVVRISGGNDKQGFPMKQGVLTHGRVRLLLSKGHSCYRPRRTGERKCKSVRGCIVDANLSVLNLVIVKKGEKDIPGLTDTTVPHRLGPKRASRIRKLFNLSKEDDVRQYVVRNSLNKDGKKPRTKAPKIQRLMTPRVLQHKRRRIALKKQRTKKNKEEAAEYAKLLAKRMKEAKEKRQEQIAKRRRLSSLRASTSKSESSQK", "length": 249 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "E1BBD9-1", "protein_name": "RNA polymerase II subunit A C-terminal domain phosphatase SSU72", "gene_name": "LOC112445820", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPFLPLRLAVVCSSNQNRSMEAHNILSKRGFSILSFGTGTNMKLPGPARDRPNVYDFRAMYDDVYKDLLRKDKERYMQNGVLRMLERNMEKEMPRPERFQECKDLFDLILTCEERVYDQVVEDMNSGEQETCQPVHVINVNILDTNKEATLGAFLICDLCQCVQLMGDMEDRIGELLQAFEEKSGRSFLHTVCFY", "length": 195 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "E1BLY1-1", "protein_name": "Small ribosomal subunit protein uS8", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MVRMNVLADALKSINNAEKRGKRQVLIRPCSKVIIRFLTVMMKHGYIGEFEIIDDHRAGKIVVNLTGRLNKCGVISPRFDVQLKDLEKWQNNLLSSRQFGFIVLTTSAGIMDHEEARRKHTGGKILGFFF", "length": 130 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "E7F638-1", "protein_name": "Moesin b", "gene_name": "msnb", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSINVRVTTMDAELEFAIQSSTTGKQLFDQVVKTIGLREIWYFGLQYQDSKGFSTWLKLNKRVTAQDVRKENPLLIKFRAKFYPEDVAEELIQEATQRLFFLQVKEAILNDDIYCPPETAVLLASYAVQMKHSDYNSEHHIPGYLCRDKLLPQRVLEQHKLTKEQWEQRIQVWHEQHKSMSREDAMIEYLKISQDLEMYGVNYFSIKNKKGSELWLGVDALGLNIYERSDKLTPKIGFPWSEIRNISFNDKKFVIKPIDKKSPDFVFYAPRLRINKRILALCMGNHDLYMRRRKPDTIEVQQMKAQAREEKNKRQQERALLENEKKRRENAEKETEKIARETMELMERLRQIEEQTKKAQEELEEQTKRALELERERKFAQEEAEKLEKDRRIAEDVKTALLQQSENQTKNKDNLATELAELTSKINLLEDAKKKKEDEARKWQRRAIMVEVDLEKTKEELKSKLIGVHIQATSQTENDHDENDESSAEASAELTSTGSFRDRSEEQRITETEKNEPLQKRLQALSSELADARDDSKKTANDLIHAENVRLGRDKYKTLRQIRQGNTKQRIDEFESM", "length": 577 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E7FA22-1", "protein_name": "Protein tyrosine phosphatase type IVA 3", "gene_name": "ptp4a3b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAWLNGLYPVEVCYNSMRFVITHNPTNQTLDTFIEDLKRYDAKTVVRVCESTYDKTPLEKHGITVMDWPFDDGAPPPTKIVDDWISLLKKSFSEDPGCCVAVHCVAGLGRAPVLVAVALIEGGMKYEEAIHLIRLKRHGAFNSKQLTYLEKYRSKKRLRFKDPFKHRSKCWLM", "length": 173 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E7FE27-1", "protein_name": "Beta-1,4-N-acetylgalactosaminyltransferase", "gene_name": "b4galnt4b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MRMRFPLKKIRKQFKLLLLLVLLMFAIGFTYLHINQGKAIKLHFNYGKDMERQAEGIGSSPKKHLSSSINPFEHGDAADSQEDGWGGEELNESAQESRANAEMHTLLAQKFLGLPWKPEYKGQANLHVFEDWCGSSVSQLRKNLHFPLYPHTRTTVKKIAVAPKWKNYGLRVFGFIHPYKDGDFQFAIASDDNSELWLSSDESPLNARLLVYVGQHGSEWTAPGEFSKFRSQTSKPVRLMSSRRYYFEVLHKQDDRGSDHVEVGWRPFLPGQKFDVIDSAYISLYTDESSLKMNSVHHIPQTLASHSLALQIYHRTETHTADMLKPDPRDTFYKIPMIDQSRLENVLPSCVYSPTYVVKDFPIARYQGLQFVYLSYVYPNDFTRLTHMEKTNKCFYRESPVYLEKFGFYKYMKMDEEEDDQPVFFPKPDDFLEEEEGVDPEEAINSSNRPVKRSGPSYQTSRITAATASSKPDRLDGGSKSSVFQQEKQYVQFKEQERSKKRTKGERFYRHSQVVDDEMTEIRQVKGSTGVLESQSGSLNEQTGPSEENGDSQTLSLVQRGRSLAWVLPDPALQSESKLIETASPTVKERSPFKLPHLYVLANRILGNAGKPVVEKESNSNKIYITRPRPPVSRPKPPVEVFPGVFLYQSRKSKRLVDLSSKWRSLKTQAAASAPWANFPLMDHKTSTQSALLKQSHLSSPTEPGPHNKGDPTASISDPDSVPPSSSEKRDHPGLNSSSQPPEEEPTKISEMAEGLDVAPQSRGLEEGEMSEYSYEEAEVRPHLAEEAINWQRTFSVNPVDFELLRSDWNDLRCNVSGNLQLAENEVIDVISQFMERLNERNRGIYTLARIVNVEKRRDSARGNRYLVELLLMEGGKRLVRLSEYIYLLLHRSRFEEGIESREGTVPSSHRTPSKIPLPSGSSAQTHTTTPWSTSWAKPLLCQPIMLQWRHDVMVHFVVPVKNQARWVQQFISDMELLHRETKDENFSVIIVDFQSDDMDVEQALKESTVPRYEYLKREGNFERSSGLQMGVDTIEDSHSIVFLCDLHIHFPHNILESIRKHCVEGRLAFAPIVMRLDCGSSPLEPDGFWEVNGFGLFGIYKSDFDKIGGMNTEEFKDHWGGEDWELLDRVLQNGLEVERLRLRNFYHYFHSKRGMWNVPVKRASQG", "length": 1167 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E7FFR8-1", "protein_name": "Ubiquinol-cytochrome c reductase complex assembly factor 5", "gene_name": "uqcc5", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLRKSQNLKYMLSLVPGKKRFGVYRFLPVFFCIGGVMEWIMINVRIGRETFYDVYRRKQSERAYQQKTEEGLIMLTDSQAK", "length": 81 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E9PUW9-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r143", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFFHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMSAFAPKTPPNELKCKLEFFSHMVARSKNLCSTCVLSIHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLQFSHDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PUZ0-1", "protein_name": "Apolipoprotein L 11b", "gene_name": "Apol11b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDWNEISEDIRKVECRTFEKVIDNATEDLITDLRSLITEDGAWNGFVEAVELSSEEGEALRDALKERLAQDPTDENDRPQREQQKERFLREFPQLKKKLEDHIRKLRDLADKFDQVHKDCTISNVVSTSASAASGVLALLGLVLSTVTAGASLALSASSVALGATSSVSSFTTTVVEDSMTLSYESEARNLIGASMNVLEEILSIMPKITCKFYNTVADLVKAFKTLKGQIQTIRRARSISRRGAQARNLTSTGRSSGQGVSQMTRGARIRAGVFTSVFLGWDVYDLVTKQRICMMGEKQSQVEHCGTWLASWRRTFRNLSRSTMLCSQTCLSDALP", "length": 337 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PV04-1", "protein_name": "Eukaryotic initiation factor 4A-III", "gene_name": "Eif4a3l1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MATTTRMATSGSARKRLLKEDGMTKVEFETSEEVDATPTFDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIMKGRDVIAQSQSGTGKTATFSISVLQCLDIQVRETQALILAPTRELAVQIQKGLLALGDYMNVQCHACVGGTNVGEDIRKLDYGQHVVAGTPGRVFDMIRRRSLTTRAIKMLVLDEADEMLNRGFKEQIYDVYRYLPPATQVVLVSATLPHEILEMTNKFMTHPIRILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQAVIFCITKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLIINYDLPNNRELYIHRIGRSGRYGRKGVAINFVKNDDIRILRDIEQYYSTQIDEMPMNLADLI", "length": 411 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PVP9-1", "protein_name": "Predicted gene 4884", "gene_name": "Gm4884", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSENLQSSPFFGTESTLHPSLPLLSNSKQPAGTVCNFSRVSTPDVSSAWLLPSASSTSLQPLMVVQMETSLGLPPSGQTYCQLQSPELCNTCVQVSQIRPPAVNGDKALTAPIHSPSQFLALPPAPSLEQPENKTMPEIKEGTKENQDTPVLTLEHPDLQQPLHCTDTESLRQKPDSDNAHLGCICMGPKELVGLENEIGSSFDFKDITRFGADIQLPQLLNTLTDIDQDQSCENWRVTSGLFDQVRENKHKSFELLEGAPQAKFQHWDLVEGEGAVGVAGASDRAIDNMAKHPEGKAPKGPPSKNRRARKQEQERPSGPENKSKKTQELKQSRNRVKAEKEPSIPKTKRKRNPPELSQNSFKKPRTNLAMHMLESVQVFHPLGKKSEKKTGISSFRGLRTFTSNKDSGPGSVTTTVLNMPCESQGPPKSPGKVQSAESSVGKDCLSPSQYELPPAGKVKLVPLPFPTLDKPQSRPASRKPLSLALRRPTAVYPVQHHSHSVQPTTLRPAQPPPASSSLIASAKPAPPISSSATGPNVTNPNQSSAVPQLATSRPVPYRASSHTSFQRELVSAARNKVPSPPRPVPYRASSNTSFQRELVSAARNKVPSPPKPQTQYLLHDFSRQPIPWKKVDILGPVVSQPITKEQRPEREAMKRRSQQERENAVKNPSTGKLQIFLQRERDMEISQYYGYAM", "length": 694 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PVW0-1", "protein_name": "Major urinary protein 8", "gene_name": "Mup8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMLLLLCVGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILASDKREKIEDNGNFRLFLEQIRVLENSLVLKVHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAQLCEEHGILRENIIDLSNAMDLVPEHVLVLTRQIAASRPENEEWPEPPVLSGDFSPGLHHHPFLSIQHPQYKFCDLHSILSH", "length": 235 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PVZ7-1", "protein_name": "Olfactory receptor", "gene_name": "Or8b3b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKYFCLPRFSIISMLTGNGSFVTEFVLAGLTDRPELQLPLFYLFLIIYTVTVVGNLGLIILIGLNPHLYTPMYYFLFNLSFIDLCYSSVSSPKMLMNFVFEKNSISYEGCMTQLFFFLFFVISECYMLTSMAYDRYVAICNPLLYKVTMSPQVCSMLSFASYGMAFAGASAHTGCMLRLIFCNANVINFYLCDILPLLQLSCTSTYVNEVVVLIVVGINITVPSFTILISYVFILANILNIKSTQGRSKAFSTCSSHIMAISLFFGSGAFMYLNHSGSMNQGKISSVFYTNVVPMFNPLIYSLRNKDVKIALKKVMMRVHSRFIS", "length": 325 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PW18-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r257", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVHDKSVKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGYKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPNELKCKLESFSRLVARSTNLCSTCVLSIHQFVTLFPLSRGKGKLILRASVQNLASYSCYSCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVLQFAHDATFMSIMIWTSVSMILLLHRHCQRMQDILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNCICIIFHAFFIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 306 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PW59-1", "protein_name": "Olfactory receptor", "gene_name": "Or8b50", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALANGSFVTEFILLGLTDQPDLQMPLFLIFLIIYLITAFGNLTLIILIVLNSHLHTPMYFFLFNLSFIDLCYSSLITPKMLMNFVLEKNIISYMGCMTQFYFFGFFAISECYVLTAMAYDRYVAICNPLLYSVAMSPKMCSYFILGSYFMGFSGAMIHTGCVMRLTFCDGNTINHYFCDLLPLLQLSCTSTYVNEIELFIVTGKDIIVPTVIIFASYGFILSNILKIRSTSGRSKAFSTCSSHIIAVSMFFGSSAFMYLKPSSAVSMNEAKFSSIFYSIVVPMMNPLIYSLRNKDVKVGLKKTLSRMFSHNLISL", "length": 316 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PXC3-1", "protein_name": "Cytochrome P450, family 2, subfamily c, polypeptide 69", "gene_name": "Cyp2c69", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDPFVVLVLCLSFMLLLSLWRQRSARRNLPPGPTPLPIIGNYHLIDMKDIGQCLTNFSKTYGPVFTLYFGSQPIVVLHGYEAIKEALIDHGEVFSGRGSFPFFDKVSKGKGIGFSHGNVWKATRVFTVNTLRNLAMGKRTIENKVQEEAQWLMKELKKTNGSPCDPQFIIGCAPCNVICSIVFQNRFDYKDKDFLSLIGKVNECTEILSSPGCQIFNAVPILIDYCPGRHNKFFKNHTWIKSYLLEKIKEHEESLDVTNPRDFIDYFLIQRRQDKGIEHMEYTIEHLATLVTDLVFGGTETLSSTMRFALLLLMKHTHITAKVQEEIDNVIGRHRSPCMQDRKHMPYTNAMVHEVQRYVDLGPTSLVHEVTCDTKFRNYFIPKGTQVMTSLSSVLHDSTEFPNPEVFDPGHFLDDNGNFKKSDYFVPFSAGKRICVGESLARMELFLFLTTILQNFKLKPLVDPKDIDTTPKYSGFSKIPPKFQMCFIPVE", "length": 491 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PXM9-1", "protein_name": "F-box and WD-40 domain protein 24", "gene_name": "Fbxw24", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEIHLSSFPMMEIFSYLDAYSLLQVAQVNKNWNALASNDFLWRKLCQERWLFCDMVTLQLLGKETWKQFFVYRTWQEHVKSRAIPEDFTYKEIPLECGVRGYAGYISGCALTRNGQGKSVVCMVSSKNKISTWDISESVITWVSPVQPASIKLLTTLPDMHIAVTVDIQSTIKLWDCHNREALATNNLESPCKSLKAVISKDGPIVLAGDILGNLYIFRIPDLHLISTVNVFPCGFDKIDCSPQKKWVLLSQNHPCIYPKVFYMSSLLRTSEFSDPVSTVLEFSLCKRAFWTPRREDRITLMSRRGRPIVTRFETFDMKLEENGNKTIVKGDLVASFSLQDYNENPKWMGVSDKSVIVCSTGSSLLLFSMKGLHLQTFQYSPEMIVRLWVDPVHVIITCNDGSIDVYMWEERSLLLKMCYRLQNGRHLPPFGFIKNLLCDDVSIVQLMIDRQGPCFLMAYTLNICS", "length": 466 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q069-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r157", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCHFEVGTVANVFLFVHNFSPVLTGYKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSVHQFVTLVPVNRGKGKLILRASVPNFANYSCYSCWFFSVLSNIHIPIKVTGPQIIDNNTYDKSNLFCSTSGFIVGIVFLQISHDATFMSIMVWTSVSMVLLLLTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPNDPCSVLFKC", "length": 297 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q0V3-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r68", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGVAIIKENQTQSKMDFWNMGIKILFLSQTTTGILGNFSLIIYYVVNYIVHTLKPTDLILMHLMTSNALMVLSTGVLHTMAAFGLAHLLNDLGCRLILYIQRVGRSTSIGTICLLSIFQAITISHRVSCYKGQKIKSSKYIGYSISLLWVLHMFLNFILFVDIFIKRNRNNMTSDRDFKYYSIVERNEFSDSLYVALVVCPEIFSSVLITCSSGSMIGILYRHKQRVQHIRSFHVSSRNSPEWRATQNILVLVSTFLAFYTLSSVLQGCIALLNNPNWWLVNITRLTSLCFPTFAPCVLMSHYSFMPRFSLVWTWNKTS", "length": 319 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q1C7-1", "protein_name": "Spermatogenesis associated glutamate (E)-rich protein 4A2", "gene_name": "Speer4a2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWMGETREGRKDADLPSKSNEGRRRWTWRMWMAHRQKTSPVPVTSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTFLHNLEMENMEARENKQELKKEKNFYRNLHTRILLEENLIKKKLAILQQESKEIHADWAIIHQRLVELNLSGKDEQEKTSNLETQEHQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPPSSSDESSSDESSYSTCPEWE", "length": 252 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q1N7-1", "protein_name": "Predicted gene 8126", "gene_name": "Gm8126", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLRRLFHRENGNQGETRPRQKESAIPSCKNRRMKSFWGRHMSAGKTSSQNCNITNHMKNRNKLDDMKFYIRKINAERLELFRILDIDMNTDLNYRMNIEFTIIKSQHEKTMLDMEKITQSINDTIEKYKEFIEDKDSYSFMHTYLLKECNQLKEKVRMLLNENRKLLVEQADQEASYGEENRFCHESSKNIHPKY", "length": 198 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q328-1", "protein_name": "RIKEN cDNA 5430401F13 gene", "gene_name": "5430401F13Rik", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASSRILLVLLSIALLALTSAQRVNEDDGSALQEEDALEIGDSNQQHDDIHERLNEIKNHFQDQISQHGKEAIKSKKGKNGPRSRRSSDDDNLEVQDHQSGNEQAGGGQGGRGRSELKGQNGKGSQKGKKGKGGQQEQKGKGGQQKQKGKGGQKTKRGKGGQRSQQDNVQEVYQE", "length": 175 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q346-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r160", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSLKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILIHMAVANALTLFLTIFPNNMSAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVPVNRGKGKLILRASIPNLWNYSCYNCWFYSVLSNIHIPIKVTGPQITDNNTDSKSKLFCSTSGFIVGMVFLQFAYDATFMIIMVWTSVSMVLLLHRHRQRMQHILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNFICIIFHAFSIHSHLFIRLVSVVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q366-1", "protein_name": "Spermatogenesis associated glutamate (E)-rich protein 4f2", "gene_name": "Speer4f2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTMCVRLRRLFQRANVDGRETREGSMDAGLPCERNEGRRRWTWRMWMAHRQTSSPVPVTSNQFEKEEEELMEEIQLISQEKNGLRDYLNLTLGSKITRLNQSYEELKLKQKELMTLQHDLEMATMEAREENEELKKEINFYSNLHSRALMENNLIKKKLMTLQQESKEVQAEWASIQQHLDVNLSGKDEQENNSILDTQEHQVSETARELGLATDQEDSILQDELPPQEAPAEELSPQEAPAEELPPQEAPAEQLPPQEGPAEELPPQESPAEHHLQHPQSFSDESSYITYPEWE", "length": 295 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q3G0-1", "protein_name": "Zinc finger and SCAN domain containing 4B", "gene_name": "Zscan4b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASQQAPAKDLQTNNLEFTPTDSSGVQWAEDISNSPSAQLNFSPSNNGCWATQELQSLWKMFNSWLQPEKQTKEQMISQLVLEQFLLTGHCKDKYALTEKWKASGSDMRRFMESLTDECLKPPVMVHVSMQGQEALFSENMPLKEVIKLLKQQQSATRPIPDNAQMPVDTTQDRLLATGQENSENECNTSCNATEVNVGESCSGNEKDSLLITQKEQNHEHEEGNVVCQFPRGARRASQDTSSHHVDFPSALTPADVPMEEQPMDLSRENISEDKNNCYNTSRNAATQVYSGDNIPRNKTDSLFINKRIYHPEPEVGDIPYGVPQDSTRASQGTSTCLQESLGECFSEKDPREVPGLQSRQEQPISDPVLGKNHEANLPCESHQKRFHRDAKLYKCEECSRMFKHARSLSSHQRTHLNKKSELLCITCQKIFKRVSDLRTHEIIHMSEKPFKCSTCEKSFSHKTNLKYHEMIHTGEMPYVCSLCSRRFRQSSTYHRHLRNYHRSD", "length": 505 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q4E0-1", "protein_name": "RIKEN cDNA 5031410I06 gene", "gene_name": "5031410I06Rik", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRVNVDGRETREGRKDADLPSERNEGRRRWTWRMCMAHRQTTSPVPVKSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTFLHDLEMKNMEARENNQELKKEKNFYRNLHTRILLGENLIKKKLAILQQESKEIHADWAIIQQRLVELNLSGKDEQEKTSNLEAQENQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPSSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q501-1", "protein_name": "Predicted gene 2237", "gene_name": "Gm2237", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLLRLFQKENVDEGETRPTEKEEGILSHEKGRRKWFWRRHRSARNTSTQNSKMTKKRSKINELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLHENVRILLNENRRLLVEQAGHKCPVGKKRGSLRRPARTSVSQVPRNSSPAESRTWH", "length": 211 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q5G7-1", "protein_name": "Oogenesin-1", "gene_name": "Oog1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVICLHCPDQDDSLEEVTEECYSPPTLQNLAIQSLLRDEALAISALTDLPQSLFPVIFEEAFTDGYIGILKAMIPVWPFPYLSLGKQINNCNLETLKAMLEGLDILLAQKVQTSRCKLRVINWREDDLKIWAGSHEGEGLPDFRTEKQPIENSAGCEVKKELKVTTEVLRMKGRLDESTTYLLQWAQQRKDSIHLFCRKLLIEGLTKASVIEIFKTVHADCIQELILRCICIEELAFLNPYLKLMKSLFTLTLDHIIGTFSLGDSEKLDEETIFSLISQLPTLHCLQKLYVNDVPFIKGNLKEYLRCLKKPLETLCISNCDLSQSDLDCLPYCLNICELKHLHISDIYLCDLLLEPLGFLLERVGDTLKTLELDSCCIVDFQFSALLPALSQCSHLREVTFYDNDVSLPFLKQLLHHTALLSQLIYECYPAPLECYDDSGVILTHRLESFCPELLDILRAKRQLHSVSFQTTKCSKCGGCYIYDRHTQCCRFVELL", "length": 496 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q6D7-1", "protein_name": "RIKEN cDNA 1700024B05 gene", "gene_name": "1700024B05Rik", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESHDNPVSAGRTSSQNCNITNHMKNMNKLDDMKFYIRKINAELEELFRILDIDMNTDLNYRMNTEFTIIKSQHEKTMLDMEKMKQSISDSIDKYKEFIEDNDSYSIRHTHLLKECNQLKEKVRMLLNENRKLLVEQADQEASFGEEKSSVMRPARTYIPSAKQQQL", "length": 167 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q7M8-1", "protein_name": "Predicted gene 5796", "gene_name": "Gm5796", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLLRLFQKENGDEGETRPKKKEEGILSHEKGRRKSFWRRHRSARNTSTQNSKMTKKRSKRNELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLNENVRILLNENRRLLVEQSGHKCPVGKKRGSLRRPARTSVSQVPRNSSVI", "length": 205 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q8A4-1", "protein_name": "F-box and WD-40 domain protein 28", "gene_name": "Fbxw28", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEIHLPSVPMMEILSYLDAYSLLQAAQVNKNWNELASSDVLWRKLCQKRWLYCYMFTLPLHGLETWKQFFFDKTWQEHAKTRAKPEDFTYKEFPVEFEFRAHPWYISRHGLTRNGQEKSAVCMTSMNRISTWDIHEGAMTWESPKQPSYIVWMTTLPEMQIAVTIDMQSTIKLWDCHNKEVLASKTGLFFGCKLLQSEFTKDGPIVLVGDACGNLYIFRIPDLHLISKVNVFPYSIDELYFSPQKKWVFLIGHRLNDLTKVFYMSSLLRPSEFSAPVSTVLKVPVIRKVFWTPRREDRITLMSLILPKNITKFDTFDMKLEGIGNKVTIQGYLTASFSLAEDEGRPDYFGVSDKDVIVCSTRFSLLLFDINGLRLQTFHYCPEEIWRLWVDPVHVIVTCDAGSLDIYAWEKRSLLLRKCYRLRNRNYQQMSGYIIKTLCDDMSIISVANNSPKPCCLMAYTLSVCS", "length": 466 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q8I6-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r55", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEMLALQILLLCQVVVGTVGNILLFVHNFSPILTDSRLRPIQVILINLAVANAFMLLLLTYSHDMIDLVPKNPPTDLKCKLAHFFHMVARGTNMCSTCVLSTYQFVTLVPGNWARVMFREISPKVVRYSCYSCWLFSVLNNAYIPMNVRGPKKSHNDSDSQGKRMCSISVVNVDMNYLQFSYDIIFIGIMVWTSVSMVIHLNRHHQRMHYIHNPNQSNRGHAETRAAHTILMLVVTFVSLYILNCICVLFHVSFVESRRWLRNVIEFLALSFPTISPLLLIFRDPRGPCSLYFNVGLEIHVTGKVITEEQ", "length": 310 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q8L6-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r132", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSVHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFFSVLSNIHIPIKVTGPQIIDNNTYDKSNLFCSTSGFIVGIVFLQISHDATFMSIMVWTSVSMVLLLLTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPNDPCSVLFKC", "length": 297 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q8T0-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSFKNVLYFQTGLGVLANTVLLFFYVFIILGHRPKPTDLISCQLSFVHIMVVLIGGDILLADIFESLNIGNDFKCKTTFYLFRVMRGLSICITCLLSVFQAVTISPNTSVLAKFKQKVKKYMTHVFLCIWFFNLSFSTNQIFYVGGFTNVSETNQMQVTKSCSLLPMNYIIRGLIFTISISRDVFLVGVMLTTSVYMVIFLFRHQRQCKHLHSFSHPRESPEKRATQTIMLLVSFFVVLYWMDFIISFTSEMLRMYDPVILTLQKFMMYAYPTITPLVQISSDNRIIIMLKNIQSKCHPSFSLKDFFFFI", "length": 311 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q8V7-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r173", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSALNKALKTTEEVALQIILLCQVGIAAVANILLLVHNLSPNFAGPQLRPKHVILAHITVGNLLIILLTGFPSNIIVFVPRNPLNDLNCKLEYFIRLVARSANMCTTCVLSTYQFIVLVPGKWSRMILRGNTSTFVHYSCNSCWIISVLNNVYIPIKISGPWNTDNDTDLNSKWVCSMSGFELVMVFLRFVHDTMFISIMVWTSVSMMLLLYRHHQSLKHIHRSNGSLGLQPEARAAYTILMLVVTFVCFYLLDCMCIFFHISFVHFRVWLRHVNEILAASFPTLSPLMLIFRGPKKISAKGINTENAFINSH", "length": 313 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q9N3-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r152", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMSAFASKTPPNELKCKLEFFSHMVARSKNLCSTCVLSIHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFGSTSGFIVGMVFLQFSHDATFMTIMVWTSVSMVLLLHRHRQQMQHILTPNQDARGQAETRATHTILMLVVTFVRFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9QAN3-1", "protein_name": "Predicted gene 1979", "gene_name": "Gm1979", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRANVDGRETREGRKDADLPPESNEGRRRWTWRMWMAHRQKTSPVPVTSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTYLHELEMKNMEARENKQELKKEKNFYRNLHTRILLEENLIKKKLAILQQESKEIHADWAIIQQRLVELNLSGKDEQEKTSNLETQEHQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPPSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9QD93-1", "protein_name": "Granzyme K", "gene_name": "gzma", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDICRNLIVFHFLVFTFFKVTVCSDVSIVGGKDVKKALSWMVSIQVNQNHKCGGILIHKEWVLTAAHCKEDSYSSVTVLIGSLSLSKGSQRIAIHNYEIPETFNKKTKKDDIMLIRLSKKVKAKPYKIPKKEKDVQPGTKCVVRGWGTTDYKGKQASDKLQMLEVLVVDRVQCNRYYNRNPVITKDMLCAGNTQQHRGTCLGDSGGPLECEKNLVGVLSGSHGCGDPKKPTVYTLLSKRHITWINKILKQQFNSTRF", "length": 257 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E9QLQ1-1", "protein_name": "Defensin, alpha, 35", "gene_name": "Defa35", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTFVLLSALVLLAFQVQADPIHKTDEETNTEEQPGEEDQAVSISFGGQEGSALHDELSKKLICYCRIRGCKRRERVFGTCRNLFLTFVFCCS", "length": 93 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F1LPT0-1", "protein_name": "Gap junction protein", "gene_name": "Gjc3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MCCSFLRQLLARESQHSTPVGRFLLPVLVGFRLLILVSSGPGVFGNDENEFMCHLGQPGCKTICYDVFRPLSPLRFWAFQVILMAVPSAIYVAFTLYHVIGYWEVPGRNKEQEAQICKGGRCKDVSGAMSLKLLWAYVAHLGVRLVLEGAALGVQYHLYGFKMPSTFICREDPCIGSTTCFQSHPSEKTILLNTMFGISGACLLFIFLELVLLGLGRVWKTYRHKLPLFKNLSTSERSVRHKDTTDDLSVVETKEPF", "length": 257 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1LT33-1", "protein_name": "Cytochrome P450", "gene_name": "Cyp2b14", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MELGVFLLLTFTVGFLLLLASQNRPKTHGHLPPGPRPLPFLGNLLQMNRRGLLRSFMQLQEKYGDVFTVHLGPRPVVILCGTDTIREALVDQAEAFSGRGTVAVLHPVVQGYGVIFANGERWKILRRFSLVTMRNFGMGKRSVEERIKEEAQCLVEELKKYKGALLNPTSIFQSIAANIICSIVFGERFDYKDHQFLRLLDLIYQTFSLMGSLSSQVFELFSGFLKYFPGVHKQISKNLQEILNYIDHSVEKHRATLDPNTPRDFIDTYLLHMEKEKSNHHTEFHHQNLVISVLSLFFAGTETTSTTLRYSFLIMLKYPHVAEKVQKEIDQVISSHRLPTLDDRIKMPYTDAVIHEIQRFADLAPIGLPHRVTKDTMFRGYLLPKNTEVYPILSSALHDPRYFDHPDTFNPEHFLDANGTLKKSEAFLPFSTGKRTCLGEGIARNELFIFFTALLQNFSLASPVAPEDIDLTPINSGAGKIPSPYQINFLSRCVG", "length": 495 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1LYQ4-1", "protein_name": "Alpha-1-B glycoprotein like 1", "gene_name": "A1bgl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDLLVLLEPLASLTLTCKVCEPSKDLHRILHLSSMETACTLSLALPPTLPSASLIFSASGVHTLILLRVRLNHSLILLSLIHTGPLPRPWLSANPVPWITPGLRTFLLCQGTVRDVVFMLRREGDDGNKEKEQGIFQVHEPGNYSCNYYTNTEYTPSKPSGTVTIKEYVIPPPPMLTSLESSTVDEPEMTQMSLLCVAPLSDVEFQLRQGEREMKVLIVSTSPERASFYLKLSDMGDHSPFTCRYRLNRMTAWSEDSKPVQLMWSDETLPEPVLTVEPSPHQSFEPGSTVQFRCTAPKAGLRSEAGLRFGLHLEDLYDHRLLQTQKSSGNETVFQLRNVSATDSASYSCIYTELTPPYSGSAPSDFVILRVNGPPPPPKLQALWTGKVFAGHDVVLRCQSDVTGVIVELLRDGKFVPYRILRVLNNYSDLGLHSVGPQHTGNYTCRYTSWLPEPVQSEPSNPVELLVEGMASGVVVVGFCLLIFPGLCILVNCAI", "length": 495 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1M6N1-1", "protein_name": "Zinc finger protein 945 like 1", "gene_name": "Zfp945l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTASLVNVSKCLLTFRDVAVEFSMEEWECLNYSQKTLYRDVMMENYNNLLFVENHCKYKKVLDQDPNSIVHNVNIYEKAYECNELVKMTHESSQGTPFKTKHKDASLQISTLNRQKIGNTRDEPCKFKDCINFLNVFVIRQNQRIYIGEKEPTTIEYENHYNSKHEVMLKQSNSTGNKPHIFRKYGQCFKIYSSFSRYQNDHTSEKFYKCIKCRKSFLHLSQLKVHYKIHYRKYPCKCTACSKCFYHTFGFKRHYSIHPEVNTYKSSDCDKSFIYYSSLRKHQKIFGGERHYECNEGLRSLYTVFQPVYYYIPHIGEKAYKCSECEKCFTRKYHLTVHQRIHTGEKPYKCGECDKCFTRKYHLTDHQRIHTGEKPYKCSECKKCFTRKYHLTDHQRIHTVEKPYKCSECGMSFMKKYHLRSHQSIHTGEKPYNCSECDKGFTYKGHLRRHQKIHTGEKPYKCSECAKCFTENSKLRRHQRIHTGENLYKCSECDRCFIENNKLRSHQKVHIGEKPYKYSEYDKCLTQKGSLRSHQLIHTGEKPY", "length": 544 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1M7A9-1", "protein_name": "Large ribosomal subunit protein uL6", "gene_name": "AABR07026048.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MANRLAHRPIQWRNFLSQDSLDQDTMRKKTILSNQTVDIPENVDITLKGRTAIVEGPRGTLRRDFNHINVELSLLGKKEKRLRVDKWWGNGKELATVRTICSHVQNVIKGVTLGFCYKMRSVYAHFPINVVIQENGSLVEIRNFLGEKYIRRVWMRTNVACSVSQAQKDELILEGNDIELVSNSAALIQQGTTVKNKDISKFLDGIYVSEKGTVQQADE", "length": 219 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1M9J5-1", "protein_name": "Uncharacterized protein", "gene_name": "Esp1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "ITFLPVTLFLIILLWPSMITEGRVLTQNQKELSISADHNKNHKSDLDKIEFQGQPNIQKAVEMTICASDKDQTLLEDQANANQDKQLYKDSHLLCGRSLDHIVK", "length": 104 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1QDL3-1", "protein_name": "Novel nacht domain containing protein", "gene_name": "LOC560232", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEDKHTPGDLDLSTGCSSVHQNRAEAEPSCVSMKSDVSMDPPTNFKSGNTGPAVSSRKRKRAEAEPSCVSMKSDASMDPPLKFKSKNTQPAVSVDRDDQSGDLLQDSLQPEHDELQRVKEQHKTTMKNKHERLFEGINHGETQTLLNRIYTQLYIIEGESEGVNEEHEVIQMEKRARTKPSQHTPVYCNDIFKASAGAGHEVKIKKEKAQIKTVLTKGIAGIGKTVSVQKFILDWAEGKANQDVDFMFVLPFRELNLIRDHQYSLHRLLLDFHPELEDLEPKIYEQCRVVFIFDGLDESRITLNFSDEEKVCAVTESSSVAVLMWSLLKGDLLPSALIWITSRPAAAHQIPSRYIKRLTEIQGFTEPQKEEYFRKRISDEHQASRIISHIRRARSLQIMCHIPVFCWISSTVLQKLLEEDVSAEIPQTLTEMYIHFLLIQINMRKQKYEERDPEKLLQSNRGVILKLAEVAFRQLMKGNVMFYEEDLIESGIDVTDALVYSGICTEIFKEESVIQQRKVYSFIHLSFQEFLAAFFVFYCHLTKKRELLELILGYSYDQYLQSSSEKSLYDLLSSAVDEAVRSSNGHLDLFLRFLLGVSLESNQRLFQDLLTHTEESSESIRRITQYIKDQIKSDDYFKRAAERFINLFLCLLEVKDQTLAREIQEFVKSDKHSEEELSPAHCSTISYMIEMSEEPLDEFELQKFNTSAEGRLRLTTAVRNCRRAL", "length": 725 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1QGM0-1", "protein_name": "Galectin", "gene_name": "lgals1l1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MPTVLIQNMAFKVGQTLTLTGVPKPESPEFTIDIGNSSEDIALHINPRFDAHGDQCIIVCNTFQNDCWCEEHRDENFPFVQGEEFQIKITFTNEEFLVTLPDGSEINFPNRQGSEKYKYMNFTGQARIQGIEIK", "length": 134 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1QMQ9-1", "protein_name": "Uncharacterized protein LOC541480", "gene_name": "si:ch1073-398c20.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MADIKQESDDIRIAEVFTLKQEDPEEQTDLLPLRKEFQGLDNVKEEEALVEEHQDITPAEKRITCSETENTTQKASEKTGSRSSFTCEQCGRDFAKQGTLNNHMRIHTGEKSFTCQQCGKGFTQKRTLRNHIRFHIEAESLSCQQCGESFTQKQDLTDHMRVHTGEKSFVCDQCGKVFLRKDGLEKHLKNHHKEKPHVCPCGKSFTDKTKLEEHTKTHTGEKPHTCDKCDECFSGKYDLIRHMRFHSAETPYICQQCGKSFALKRVLMTHVKIHTRDRPFLCKQCGKCFYRKDNFNRHVRVHTGEKPYACSECGKSFSERFQFNEHSRTHSGVKRFSCEQCGRGFNRKTELKRHMRVHTGEKPYMCPQCGKTYAFKTGFDIHMLHHNAEMPYICPQCGERFSVKQRFDVHMKIHAGNSDK", "length": 420 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1R1Q6-1", "protein_name": "Uncharacterized protein LOC641576", "gene_name": "zgc:152710", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MVLIWTQFGVKHKNVKCKVRVIHGEEGSWSSEEVREEPEVSSPPPSPECVDYYSVLGVSNDSNEEEIRKAYKRLALRYHPDKNSDADAEDKFKQIAQAYDVLTDPEKRNIYDQQGLTKGGVAPTCNKTDPSHNSKADAHSWHMFFNFDLDSDDDLFNPFTRNPLPHLSRHHGNKGGLKPAGDAEVHDLSVSLEDILMGVTKRVKLTRLRQTDKHTLKPEERVFDVEVKKGWKEGTRITFPNEGHQMLGHAPNDLAFVIKEKKHAHFRRDGSHIVYTCTITLREALCGCTVNVPTLDGQMKPLPCSDVIKPSSVRRLIGEGLPRAKNPAQRGDLLVEFQVVFPDRIPPSSKEIIKHSLGQC", "length": 360 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1RA39-5", "protein_name": "[F-actin]-monooxygenase mical2b", "gene_name": "mical2b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGETEEERTSQAGQLFENFIQATTCKGTLQAFSVLCRQLELNPSDHRGFYSSLKTAVTFWKAKGLWGKLDKRAGHKEYSKGRACADTRCLIIGGGPCGFRTAIELALLGAKVVVIEKRDTFSRNNVLHLWPYTIHDLRNLGAKKFYGKFCAGSIDHISIRQLQLMLLKIALIVGVEVHVNVEFVKLLEPPEDQSTDGQGWRAEIRPADNPVSDYEFDVIIGADGRRSTLDGFRRKEFRGKLAIAITANFVNRNTTAEAKVEEISGVAFIFNQKFFLELKEETGIDLENIVYYKDNTHYFVMTAKKQSLLDKGVIINDYIETERLLAFDNVNQEALLSYAREAADFGTNYQLPSLDYAINHYGQPDVAMFDFTCMYASENAALVREKSHRQLLVALVGDSLLEPFWPMGTGCARGFLAAFDTAWMIKGWAQGKEPLDLLSERESIYRLLPQTTAENISKNFEQYTIDPATRYPNLNSSCVRPHQVRHLFISGEQDLSSLERSGQTRRSVSISRRESEVRPGRLLLWCQNQTQDYRGVNVTDLNTSWRSGLALCALIHRQRPELIDFDSLNEADCAKNNQLAFDVAEREFGIQPVTTGKEMDAERGPDKLIMVLYLSKFYEMFHKSTQSVTGLPKEIDANNGDCSSKTANSLYNSINHARKRIPKLDKKLEESDVNRKRKKASSHHEELMSCQTAPPAGEREEQKENKVRSMATQLLARFEENAPSCALRRQSDSESDSDADRPVSLDLTENPRFARPKIEPTHPSTTPDKAKWQPSPYLRLLESNTRSETLHTEHYVESQSSHRLTEIQSECQYSSVSSAYKSSERRPRSPLIPFTPTLSPMMHCLQQLEEQVIQQRKREPLNRKSIKERAQKLSSLFTGNPAQPQTDESSPAVSPSSPPQTIPESSTLSCLLSPAPSLTHKQCSEASETHLKADKHTEIRRVERLDPSKQRTVGKVSSAIGVKAATLAILYETDHRPNNPITLSLTEARRCAESGLVSVRKEFSASLGGSDTCVFCQKRVYIMERLSAEGFFFHRECFRCHICGCSLRLGAHTFDSQQGTFYCKMHFSQRKTSTRHRRGEIQDGGIRSSSITISNHTSTDGTRGQPSGGEFDSSTQQDLQTLPDSKEIISVSEVKDSSKKADPADSAPACPDSPLQKVKRSTAKGEITNKNILWKKKIRSTLPLVLMKKFHRGKPEDKTEVLAEEDGNSDFEEIHESLSSKKPSNPSTDSNCLPTKDNSSTPLDEIPKIPLYRTHVLPEYPKPSSSSPEPIVTSISSDPISFSPKKKLTLSLSEKEKLLNWDLTNPGKSGAEEQQQQHVKPSISLQHDHPEPTHPQPEPAPPLFGFQQWANNLRKSFSKGSNPVVLRRNRPMKARPLSEGSFNVGAVFQDEERCGSLVDEGEARPRTESEIASLLEQVALGSKTSRGTKDDMASLPPRKLNFFSSLRIKRVEGAEQSRGEGQKDILSILSRFRNKASAQQQQQQKSNSSSEDEQEPKLTHSGALQKKKEKIAIRQTKSDELKRLHRAQVIQRQLEEVEEKQRSLEEKGVALEKVLRGENGDDGSTDEAALLQTWFKLVLEKNKLSRYESELMIFAQELELEDTQSRLQQDLRRRMATEDCEKSASELVEEQNILVEIMKVVEKRDKLVSLLEEQRLKEKAEDRDLESLILSRGYQFHWT", "length": 1679 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1RXL1-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100152495", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MFTICNDSHSDFILLGFSDKPYLEKILFWVVLIFYCLTIIGNLVIILVSLKDPKLHIPMYYFLSNLSLLDLCFTSSCVPQMLVNFGGPEKTISYIGCAIQLYVFLWLGATECVLLVVMAVDRYVAVCHPLQYTTIMHPKLCLELAILAWGTGLIQSLTQSPATLQLPFCSNRRLYDIVCEVPALIQVSSADTIYNEIQMSIASIILLVVPLVIILSSYGAITKALLRVKSTEGQKKAFGTCTSHLLVVFLFYGTVTAVYLQPKSHYAHEQGKFLTLFYTVITPTLNPLIYTLRNKEVKGALIRLGKKTWDDLCWTIA", "length": 317 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1RYD0-1", "protein_name": "Transcription elongation factor A like 3", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRQVKHLRSGSLPTPGLSVTSPSPTARPATPRTACLFPALCKTRKGEGTCPESLQDKKRRKNLNMEKLCKENEGKPESEGKPEDEVEPDNEGKSDEEEKPEVEGKSAHEGKLQNEGQPEDEGKPEDEGKQEKQGKSEDEGKPPGEGTMESQAKPESEPRAAEKRPAEDYVPRKAKRKTDRVTDDSPKDYEEDLQERHLGSEEMMREGGDLSRAQEELRKRQKMGGFHWMQRDVQDPFTPRGPRGVRGMRGGGRSQRGLHDIPYL", "length": 264 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1RYD7-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258723", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "LLVVVLVTYLLTLVGNTVIILIASIDPNLKTPMYFFLTHLSLVDICLTTSIVPQLLWNLRGPAKTITTLGCAVQLYVSLALGSTECVLLAVMAFDRHAAICKPLHYAAVMNPRLCQALAGVAWLSGVGNALIQSTVTLWLPRCGHRRLHHFFCEVPSMIKLACVDIHTNEVQLFIASLVLLLLPLALILTSYGHIVKAVTRIKSVQAWRKALGTCGSHVMVVSLFYGTITAVYIQPNSSYAHTSGKFISLIYTVLTPTLNPLIYTLRNKDVKGAMRRLFRRDLGS", "length": 285 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1S4M2-1", "protein_name": "Small ribosomal subunit protein uS13", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSLVILEKFQHILRVLNTTIDGWQKIAFATTAIKGVGRRYAHVVLRKADIDLTKRAGELTEDEVEHVITIMQNPGQYKIPDWFLNRQKDVKDGKYSQVLANGLDNKLHEDVERLKKIRAHRGLRHFWGLRVGGQHTKTTGRRGHTVGVSKKK", "length": 152 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1S6C0-1", "protein_name": "RING-type domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGNCLTPHTSEDLLVPASATHLGGRRRRARSRERRPRDQVPGWAPAAPLVQEEQVRVPQRISQIQCLPKGVYKRDGSQEKMEQEECAICTLDFVCGDPIRSLPCKHFYHLGCIDEWLTRSFTCPYCRGPADGPQPSSRDTP", "length": 141 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1S7I2-1", "protein_name": "Beta-defensin", "gene_name": "DEFB125", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MNLLLTFMICGLLTLVTKAGWNVERCWSYNIGHCRRRCLHLERYKHLCMNKRACCIPLSSDDPYTQWPLPPEDQTVGMKTPYFRPVSPGSELDDQITITITVDQESTGTEQDIEGTAISFQASTPIPENIEDTKFSDKANTLNLHKL", "length": 147 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1S7N4-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100152708", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDQTNSSVVTEFVLVGLTQSLGMQFLLFLLFSTFYVGIILGNLFIVFTVISDSHLHSPMYILLANLSLIDLGLSSTTVPRMISDLFSDCKTISFHNCMIQMFFIHVTGGVEMVLLIAIAYDRYTAICKPLHYLTIMNPQMCMLLVVAAWITGVTHAVFQFAFVINLPFCGPNNVGSFYCDFPRVIKLACIDNYGLEFVVTANSGFLSTGTFFLLVVSYIFILVTVRQHSSKDLSKAFFTLSTHITVVFLFFLPCMFLYVWPFPTKSLDTFLAIVDFAVTPVLNPAIYTLRNRDMKVEMRRLSRQVISSREMT", "length": 312 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SBB9-1", "protein_name": "DNA-directed RNA polymerase RBP11-like dimerisation domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MHALPAFESFLLFKDEKITIHKDTKAPNACLFTIDKEDHTLGNVIKSQLLKDPQVLFAGCQVPHPWEHKIIVPVQTTPDYTPQEALLNVITDLISKLSLLEERLRVAIKDKQEGIECWTGRGPAWPGPALTLALLQAPCG", "length": 140 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SBV4-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100154723", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MESENITVVTEFIFVGLTQSRNIQLLVFVLVFIFYLIILPGNFLIILTIRSDPGLTAPLYFFLGNLAFLDASYSFIVAPRMLVDFLSEKKVISYRGCITQLFFLHFLGGGEMLLLVVMALDRYIAICRPLHYSTVMNPRACYALSLAQWLGGFVHSIIQVALILHLPFCGPNRLDNFFCDVPQVIKLACTDTFVVELLMVFNSGLLTLICFLGLLASYAVILCRVRGSSSEGKTKAMSTCTTHIIVIFLMFGPGIFIYTRPFRAFPADKVVSLFHTVIFPLLNPVIYTLRNQEVKTSLKKLLINN", "length": 305 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SJ79-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110259717", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEQNNGTKGTEFILLGFAGQHKSWPVLFIVFLVTYVVTLVGNIGMILLIKIEASLHTPMYFFLQNLEEKVDLCYATAITPKMLQNFVWTEHSISFIGCMVQLLTYGAFATSDCYILAAMAVDRYVAICNPLRYPTVMSQRVCIQLVIGSYFMGFLNASVNTSFTFQLNFCKSNKINHFFCDAPPILALSCSSIYFSIMLLAAFVGFNLTCTVSVVIFSYVFILAAILKISSAAGRKKAFSTCASHLTAVTLFYGTLSYMYLHHRTLESQEQEKLASVFYGIVIPMFNPLIYSLRNQDVREALKGVGKQCF", "length": 310 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SLL7-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRRENQSSISKFLLLGLPIQPEHQGMFFVLFLVMYLTTVLGNLLIILLIRLDPRLHTPMYFFLSHLALTDVSFSSVTVPKMLMNMQTQDQSIPYAGCVTQTYFFIFLACIDNLLLAVMAYDRYVAICHPLHYAIIMREELCLCLLVLSWLLSCAYALTHTLLLAQLSFCADIIPHFFCDLDALLKLSCSDTSLSELVTFTAGAAVVIFPFIGILVSYGHIGLSILRVPSTKGICKALSTCGSHLSVVSLFYRTSMAVYLSSSGQFHDKDIIVSVMYTVVTPMLNPFIYSLRNRDMTLALGILFRNINIFSK", "length": 311 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SMZ6-1", "protein_name": "10 kDa heat shock protein, mitochondrial", "gene_name": "HSPE1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAGQAFRKFLPLFDRVLVERSAAETVTKGGIMLPEKSQGKVLQATVVAVGSGSKGKGGEIQPVSVKVGDKVLLPEYGGTRVVLDDKDYFLFRDGDILGKYVD", "length": 102 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SRB7-1", "protein_name": "Large ribosomal subunit protein eL31", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAVVQKSGEKKRGRSAINEVVTREHTTSIHKRIHGVGSKKRAPRALKEIRKFAMTEMGTPDVRNDTRLNKAVWAKGIRNVPRRICAPLSRKRNEDEDSPNKLYPLVTCVPVTTFKNLQTVNEDEN", "length": 125 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SUB9-1", "protein_name": "Multifunctional fusion protein", "gene_name": "IL1B", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MATVPEPAKEVMANNGDNNNDLLFEADGPKEMKCRTQNLDLSPLGDGSIQLQISHQLCNESSRPMVSVIVAKEKPMNPSSQVVCDDDPKSIFSSVFEEEPIVLEKHANGFLCDATPVQSVDCKLQDKDEKALVLAGPHELKALHLLTGDLKREVVFCMSFVQGDDSDDKIPVTLGIKGKNLYLSCVMKDDTPTLQLEDVDPKSYPKRDMEKRFVFYKTEIKNRVEFESALYPNWYISTSQAEQKPVFLGNSKGRQDITDFTMEVLSP", "length": 267 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F2Z5L2-1", "protein_name": "Histone H2A", "gene_name": "H2AC18", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSGRGKQGGKARAKAKSRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYMAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGKVTIAQGGVLPNIQAVLLPKKTESHHKAKGK", "length": 130 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F4IWB9-1", "protein_name": "Cytochrome P450, family 705, subfamily A, polypeptide 28", "gene_name": "CYP705A28", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MIMGRSCSEKNGEAERVRGLVIESLALSPKIFLGMIFHKPLKKLGISLFQKDIKSVSPKFDELLEKFLVEHEEKMEEDHYKANDMMDLLLEAMEMRMQNVNLCIKRVSNTKARKPPILFRYGKYSNNSLLLQELLVAGTDTSALATQWTMAELINNPTILERLREEIESVVGNTRLIQETDLSNLPYLQSVVKEGLRLHPPASISVRMSQERCELGGFYIPEKTLLVVNTYAIMRDPNFWEDPEEFKPERFITSSRSEQEDEMREEVLKYIPFSAGRRGCPGSNLAYVSLGIAIGVMVQCFDWRIKGEKVNMSETAGTIMLAMAQPLKCTPVPRTLNLLPSSLHIPSS", "length": 348 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "F4J311-1", "protein_name": "Zinc finger (C2H2 type) family protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDLDGVELLLDLREMVSQSGFEKSTTCSGVIALRSNLQSKSSHKCKICGKSFECYQALGGHQRIHRPIKEKLSKQEFSEVYPRKSKLQKRPESSSSCYECKVCGKIFGCYRGLGGHTKLHRSTKRELASTQDENSLLDSSEAKKIVSQPSSFKVSQEEKFLHCVELKQDFSEPLSHSGALPSTLRSKLQTKTQWKSSCHCKICGKSFVCSQGLGNHKRVHREISGKLACKRKYTEDYNPFSDSLKAKKIVKKPSSFEVSQEEKILHCVELKQDFGELLAHSGFDKSISCSKSIKVKKVARKNEKTEDSTSLFGVFVGEMSQRLHGCKTCGRKFGTLKGVYGHQRMHSGNHNRIEDENGLERIWGLKKKSRVCSVSAFDRFKGSSFMAEIEKHEVIEAALNLVMLCQGVYDFASISNLPLGDGFMDLELKPCPLRRKLQKKSRSSYKCSICEKSFVCSQALGSHQRLHRWKLVPKPEYIEDDSSLLDSSEAKKIVSKPSSFEHAQEEKILQCVEPKLEFHEQLAHSGFDKFDTCSKIRFSALPSPPEAKKIVSQPPSFEVSVDEKILYRAEPKLNFSEPLAHSCFDNSSSYRSIICGKSFVCSQALGGHQTLHRSIKGQLAGTEDGNSLSVTDSEASKIVAQPSSYKSQGI", "length": 650 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "F4JLV4-1", "protein_name": "Protease inhibitor/seed storage/lipid transfer protein (LTP) family protein", "gene_name": "DHYPRP1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MASTTIILFLSFSIIPLLTIVRADNHSVYCPPPPPCICICNPGPPPPQPDPQPPTPPTFQPAPPANDQPPPPPQSTSPPPVATTPPALPPKPLPPPLSPPQTTPPPPPAITPPPPPAITPPLSPPPPAITPPPPLATTPPALPPKPLPPPLSPPQTTPPPPPAITPPLSPPLVGICSKNDTELKICAGILAISDGLLTTGRAEPCCSIIRNVSDLDAVTCFCKSVGAPRFSLSPNFGIFFKVCGRRIPQGFSCPGPSPTISPPPLPPQTLKPPPPQTTPPPPPAITPPLSPPLVGICSKNDTELKICAGILAISDGLLTTGRAEPCCSIVRNVSDLDAVTCFCKSVGARRFSLSPNFGIFFKVCGRRIPQGFSCP", "length": 375 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "F4K5R6-1", "protein_name": "Cell division cycle 20.6, cofactor of APC complex", "gene_name": "CDC20-6", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MMKSIALALCLTHHSPMVLSIVDYGDSQEKTIDSLWKKPHGSDLTWSGFSRVGVTEAYFAVPVDHFLTNPPSLRLSQTIYCRRGSSYVETEKVEEEDRDDFLKQVWFLTDNLVFFFVDIEEYIVIEQLGDTVYLWDASSCYTSKLVTIDDENGPVTSINWTQDGLDLAVGLDNSEVQVWDCVSNRHVRTLRGGHESRVGSLAWNNHILTTGGMDGKIVNNDVRIRSSIIGTYVGHTEEVCGLKWSESGKKLASGGNDNVVHIWDRSLASSNPTRQWLHRFEEHTAAVRALAWCPFQASLLATGGGVGDGKINFWNTHTGACLNSVETGSQVCSLLWSKSERELLSAHGFTQNQLTLWKYPSMVKMAELNGHTSRVLFMAQSPDGCTVASAAGDETLRLWNVFGEPPKTTKKAASKKYTEPFAHVNHIR", "length": 428 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "F5H284-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase A-like 4D", "gene_name": "PPIAL4D", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVNSVVFFEITRDGKPLGRISIKLFADKIPKTAENFRALSTGEKGFRYKGSCFHRIIPGFMCQGGDFTRPNGTGDKSIYGEKFDDENLIRKHTGSGILSMANAGPNTNGSQFFICAAKTEWLDGKHVAFGKVKERVNIVEATEHFGYRNSKTSKKITIADCGQF", "length": 164 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "F6R3J9-1", "protein_name": "Spermatogenesis associated glutamate (E)-rich protein 1G", "gene_name": "Speer1g", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWRARRHTSSTAPDLSKKEFKKEKERLTTELHLLIQLRNEQRDHLIDFKESSNYNRTKPTQKKNPFYEQLRSTKNQVLSSVHKLEMGIIEAQENIQELNKWIDYFTNLHSQLLMEKNLKMSITQNKKNKEVEIDWALIEKYLVDLNLNGQTGADQQP", "length": 157 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F6X687-1", "protein_name": "Spermatogenesis associated glutamate (E)-rich protein 1A", "gene_name": "Speer1a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWRARRHTSSTAPDLSKKEFKKEKERLTTELHLLIQLRNEQRDHLIDFKQSSNYNRTKPTQKKNPFYEQLRSTKNQVLSSVHKLEMGIIEAQENIQELNKWIDYFTNLHSQLLMEKNLKMPVTQNQKNKEVEIDWALIEKYLVDLNLNGRTGADQQP", "length": 157 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F6YNI8-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad19", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRCRGKNENESEKRELVFKEYGQEYAQVTKMLGCGRLEAMCFDGVRRLCHIRGKLRKKVWINTSDIILVGLQDYQDNKADVILKYNLDEARSLKAYGELQEHAKINETDTFGPGDDDEIVFDDTGDDDEDIDDI", "length": 144 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F7AMQ8-1", "protein_name": "Exocrine gland secreted peptide 8", "gene_name": "Esp8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEKVSAMTSFPVMLFLIILLLPSICSEERTQADPTISADNKKNFKTVVDLTDCQCERNFIESLESTLPASNQDQTLFENMTNQHKLNLSKMLSVLSKCCTQKQQVDTVHFRRMPHRIQSTKQNNYKKQVLYPMQEFMNLTRDVLVSRYV", "length": 149 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F7C9P2-1", "protein_name": "F-box and WD-40 domain protein 25", "gene_name": "Fbxw25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEIHLPSLPMLKILSYLDAYNLLQAAQVNKNWNALASSDVLWRKLCQRRWHYCDMVTLQLQGKETWKQFFIYRIWQEHAKTRAKPEDFTYKEIPVECGFYGYACYISGHGLTRNGQGKSVICMVSSKNTISTWDIHKSVITWVSPVQPASINLLTTLPDMHIAVTVDIQSTIKLWDCHNREALATNNLESPCKSLKAVISKDGPIVLVGDTLGNLYIFRIPDLHLISTVNVFPYGFDEIDCSPQKKWVLLSKNYPHILPKVFYMSSLLRTSEFSAPVSTILEFSLCQGAFWTPRREDRITLMSRSGFPQITKFETFDMKLEGIGNKVAVQGKLIASFFLPYYEESPNWIGVSDKDVIVCSTHFFLLLFTINGLHLQTFQYCPETIVRLCVDPVHVIVTCNNGSLDVYAWEERSLLLRKCYRLQNKRPLPLYGFINNLLCDDVSIVQLMRDGHGPYSLIAYALNICS", "length": 466 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F7ELE5-1", "protein_name": "NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial", "gene_name": "Ndufs7", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "RRTVVYTARARSQEKSGSEPLSLWFRFPLVSIWALDQNRNSLEDGPQRLSEGRGQDGGAGGSWLALCTDPGSAHRHSGSAAQSPPECGSHWEPEQSAVSKAGAGAVVPKPSHLPRSRAEYVVTKLDDLINWARRSSLWPMTFGLACCAVEMMHMAAPRYDMDRFGVVFRASPRQADVMIVAGTLTNKMAPALRKVYDQMPEPRYVVSMGSCANGGGYYHYSYSVVRGCDRIVPVDIYVPGCPPTAEALLYGILQLQRKIKREQKLKIWYRR", "length": 271 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F7F947-1", "protein_name": "Beta-defensin-like domain-containing protein", "gene_name": "Spag11b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDLSQRPPNVFRHVVDFLKKNQTHITQACSGNSGGRKASSSDLCGCALCLEAPSPHSQLSYKRACSSCPPTRGSSVPAVPSTAMKQRLLPSFVNLLLAALLLPGKAETWLRSWTQALSAVVTLGSSSASSINHLVTEPPSSPQDEFPAQGGNGSGLLHHRVKRFPPRTPPYHEPGPNYQIVNCKKNEGFCQKYCNFMETQVGYCSKKKEACCLHPF", "length": 216 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F7FNC4-1", "protein_name": "Interleukin 36, gamma", "gene_name": "Il36g", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSKYPHSPCTASGKETPDLGQVSDVDQQVWIFRDQALVTVPRSHTVTPVTVTVLPCKYPESLEQGKGTPIYLGIQNPDKCLFCKEVNGHPTLLLKEEKILNLYHHPEPMKPFLFYHTLTGATSTFESVVFPGSFIASSKIGKPIFLTSKKGEHYNIHFSLDII", "length": 164 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F8VPX6-1", "protein_name": "Spermatogenesis associated glutamate (E)-rich protein 4A1", "gene_name": "Speer4a1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRANVNGRETREGRKDANLPPESNEGRRRWTWRMWMAHRQTTSSVPVTSKKQFEKEEKELIKKIQLTTKETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTYLHNLEMENMEARENKQEFKKEKNFYRNLHTRILLEENLIKKKLAILQQESKEIHADWAIIQERLVELNLSCKDEQEKTSNLETQENQVSEAARELGLATAEEDSILQNELPCQEAPAEHHTQNPPSSSDESSSDESSYSTCPAWE", "length": 267 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F8VQM2-1", "protein_name": "C-C motif chemokine ligand 26", "gene_name": "Ccl26", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFFDLGLLVLLAIFLSVQLGVATCGSSIAMSCCPNFSYYVIPWSWVYSYKFTDKSCTSDGVIFFTKTGKQFCVQPGAKWVQRFISLVNTRNHL", "length": 93 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "G3GSG1-1", "protein_name": "Ferritin", "gene_name": "LOC100767129", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MGFLRKSHRRQRHRCPLRVSRATVAYPLVFMTPPIISPPSQVRQNYHFDCKTAVNNHVQLQLHNSSVYLAMAFYFDSEDVAQKNLASFFLNKSHECTAQAEMFLELQNQRGGRISLGSIREADRNNWLGGLQAMECALQLELSTNQSLVALHQLASSKSDAHLCSFLKNHFLTKQVEVLKEISGYVTKLRQMGSPDDGIAEYLFGKLTLDDNKGK", "length": 215 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3GWA3-1", "protein_name": "60S ribosomal protein L18a", "gene_name": "LOC100764432", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MKASGTLREYKVVGRCLLTPKCHTPPLYLMRIFALNHVVAKSRFWSQLKKMKSSGEIVHCGEVRPEVPLQVKNFAIWLHYDSRNGTYNMCREYWDLTVTQCYRDMGAQHCARTHCIHIMKVEEIASGKCQRPAVKQFHDSKIKFLLPHRVLRCQHKPHFTTKRLNTFF", "length": 168 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3H156-1", "protein_name": "Prefoldin subunit 4", "gene_name": "LOC100773780", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MVATMKKAAAEDVNVTFEDQQKINKFARDTSRITEQKEIEVKKNHLQNLEDTFNDIMLADGDCFMTQYLIRDVLISHSQEEAQEMLEEAKKTLQEEIDALESRVGAIQWVLANLKVQLYTKFGSNINLGVDES", "length": 133 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3H2T6-1", "protein_name": "Histone H4", "gene_name": "LOC100757199", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG", "length": 103 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3H8X2-1", "protein_name": "1-acyl-sn-glycerol-3-phosphate acyltransferase gamma", "gene_name": "Agpat3", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MGLLAYLKTQFVVHLLIGFVFVVSGLVINFTQLCTLALWPISKQLYRRINCRLAYSLWSQLVMLLEWWSCTECTLFTDQATVDHFGKEHAVIILNHNFEIDFLCGWTMCERFGVLGSSKVLAKRELLCVPLIGWTWYFLEIVFCKRKWEEDRDIVKEGLQCLSDYPEYMWFLLYCEGTRFTETKHRISMEVAASKGLPPLKYHLLPRTKGFTTTVQCLRGTVAAIYDVTLNFRGSKNPSLLGILYGKKYEADMCVRRFPLEDIPADENDAAQWLHKLYQEKDALQEMYKQKGVFPGEPIKPARRPWTLLNFLCWATILLSPLISFVLGVFASGSPLLILTFLGFVGAASFGVRRLIGVTEIEKGSSYGNQELKKKE", "length": 376 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HAB3-1", "protein_name": "40S ribosomal protein S15", "gene_name": "LOC100759804", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAEVEQKKKRTFRKFTYCGVDLDQLLDMSCEQLMQLCSTRQRLLLNCSLWRKQHSLLKSLRKAKKKVPPMEKPEVGKTHLRDMIILPEMAGSMVDVYNGKTFNQVEIKPKMIGHYLGEFSITYKPVKHGGPGVGATHSSRFIPLK", "length": 145 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HDI6-1", "protein_name": "Lipid transferase CIDEB", "gene_name": "Cideb", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEYLSALNPNGLLRSVSTMGSELGRRVWNSGPPPQRPFRVCDHKRTVRKGLTAATRQELLDKVLETLLLSGVLTLVLEEDGTAVESEDFFQMLEDDTCLMALERGQSWSPRSGMLSYGLGREKPKHSQDIARITFDVYKQNPRDLFGSLNVKATFYGLYSMSCDFQGVGPKKVLRELLRWTSSLLQGLGHMLLGISSTLRHVVEGAERWQWHKQNHLRS", "length": 219 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HDS5-1", "protein_name": "Histone H3", "gene_name": "LOC100773314", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MARTKQTARKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVMALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA", "length": 136 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HGI3-1", "protein_name": "PHD finger protein 6", "gene_name": "Phf6", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSSSIEQKKGSTRQRKCGFCKSNRDKECGQLLVSENQKVAAHHKCMLFSSALVSSHSDNESLGGFSIEDVQKEIKRGTKLMCSLCHCPGATIGCDVKTCHRTYHYHCALHDKAQIREKPSQGIYMVYCRKHKKTAHNSEADLEETFNEHELEPSSPKTKKKSRKGRPRKTNFKGLTEDSRSTSSHGTDEMESSSYRDRSPHRSSPNDTRPKCGFCHVGEEETEARGKLHIFNAKKAAAHYKCMLFSSGTVQLTTTSRAEFGDFDIKTVLQEIKRGKRMKCTLCSQPGATIGCEIKACVKTYHYHCGVQDKAKYIENMSRGIYKLYCKNHSGNDERDEEDEERESKSRGRLAIDQQLTQQQLNGN", "length": 364 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HJW3-1", "protein_name": "Calcium homeostasis modulator protein 6-like", "gene_name": "LOC100774768", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEKFKAVLDLQSKHRSALGYGLVTLLTAGGEKIFSEVVFQCPCSATWNLPYGLVFLLVPALALFLLGYALRTRTWRLLTGCCSWSASAQSSSGLQRVFVCAQISAAAALPPLTWVAVALLGGSFYQCAVSGSEAMARHLCKGRDPSCAAKLPQVPCKKQEAEMQDILSQLKAQSQVLGWILIAAIIILLLVVKSVTRCLSPVSYLQLKFWEIYLEKERQILQGEAMEHATQLAKENVRCFFDCTNPKDCSTPSSKAWQQISALYTFNPKNHFYSMLHKYVNRKDMSGSLRSVEGDAVVPVLGFVDASGMATTHGV", "length": 315 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HQ40-1", "protein_name": "Eukaryotic peptide chain release factor GTP-binding subunit ERF3B", "gene_name": "LOC100767578", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDLGSSSDSAPDCWDQVDMEVPGSAPSGDGFTSASTAAAEAAEAEAQRQHLSMAFSSQLNIHAKPFVPRVSAAEFVQSFLPGSAQPPAPTTSSSDETCTGAGDPQGKRLGWGAPVEPSKDGPLMSWEGSNSAVTMELSEPVVENGEVEMALEESWELKEVSEAKPGGSLGDSGPPEESGKEMMEEKEVIRKSKSMAIPSGAPKKEHVNVVFIGHVDAGKSTIGGQIMFLTGMVDRRTLEKYEREAKEKNRETWYLSWALDTNQEERDKGKTVEVGRAYFETEKKHFTILDAPGHKSFVPNMIGGASQADLAVLVISARKGEFETGFEKGGQTREHAMLAKTAGVKYLIVLINKMDDPTVDWSSERYEECKEKLVPFLKKVGFSPKKDIHFMPCSGLTGANIKEQSDFCPWYTGLPFIPYLDSLPNFNRSIDGPIRLPIVDKYKDMGTVVLGKLESGSIFKGQQLVMMPNKHNVEVLGIVSDDAETDFVAPGENLKIRLKGIEEEEILPGFILCEPSNLCHSGRTFDVQIVIIEHKSIICPGYNAVLHIHTCIEEVEITALISLVDKKSGEKSKTRPRFVKQDQVCIARLRTAGTICLETFKDFPQMGRFTLRDEGKTIAIGKVLKLVPEKD", "length": 631 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HQN5-1", "protein_name": "Transcription factor 19 isoform X1", "gene_name": "Tcf19", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MLPCFQLLRIGGGRGGDLYTFHPPSRSGCTYRLGCRADLCDVALRPQQEPGLISGVHALLHAELQGDDWRVSLEDHSSQGTLVNNVRLPRGHRLELSDGDLLTFGPEGQAGTSSSEFYFMFQQVRVKPQDFAAITVPRSRGEAGTGFQPMVPSQGAPQRPLSTLSSAPKATLILNSIGSLSKLQPQPLTFSRGGGRPQSLAVPTQPGEVGASPPAPPTRNRRKSVHRVLAELDDENETSLSPLSVLMEPRKKLRLEKAALVSSGRD", "length": 266 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HWQ5-1", "protein_name": "Zinc finger protein 219", "gene_name": "Znf219", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEGSRPRILVGHLEPSPPAFDGELDLQHYSNGPGVSTGSPGMGAVGWSETRAGERRFPCPVCGKRFRFNSILALHLRAHPGAQAFQCPHCGHRAAQRALLRSHLRTHQPERPRSPAARLLLELEERALLREAQLGRARSSGGMQATPATEGLARPQVPSSSAFPCPFCKGKFRTSAERERHLHILHRPWKCSLCSFGSSQEEELLHHSLTAHGASERPLAATSTPEPQPPPQPEPRSALEPEPEPEPRPEPEHEANPAPTPAPPEEPPAPPEFRCQVCGQSFTQSWFLKGHMRKHKASFDHACPVCGRCFKEPWFLKNHMKVHTSKLGPLRAPGPGSTPARAPQPPDMSLLAYEPLGPALLLAPAPTPAERREPPSLLGYLSVRAGEVRPNGEGADPGAGRSYGGGFRPLPSALPNRARRHRTEEPEEEEEVVEAEEESWARGRSLGTLTSLHPHPGEGSGQSAPAVGAQARPTGTQEENGLLVGGARSEAGRGATGKDCPFCGKSFRSAHHLKVHLRVHTGERPYKCPHCDYAGTQSGSLKYHLQRHHREQRSSAGPGPPPEPPPPSPRGAASLQPQSGAKPTQASATWVEGTASTRPSSSGTGAGSRRKPASPGRTLRNGRGGEAEPLDLSLRAGPGGEAGSGGALHRCLFCPFATGAPELMALHLQVHHSRRARGRRQPRADTSPPYVRAPSGETPPSPPLEEEGSPGLSRSGEAGLGGQER", "length": 725 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3I071-1", "protein_name": "Large ribosomal subunit protein uL29", "gene_name": "LOC100753244", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAKIKARDLRGKKEELLKQLDDLKVELSQLRVAKVTGSAASKLSKIRVVQKSIVRVLTVINQTQKENLRKFYKGKKYKPLDLRPKKTRAMHRQLTKHEEKLKTKKQQRKERLYPLRKYAFKA", "length": 122 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3I1Z3-1", "protein_name": "DNA damage-inducible transcript 4 protein", "gene_name": "Ddit4", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MPSLWDRFSSSSSSSSSSSSGTPATDRPPRSAWGSAAREEGLDRCASLESSDCESLDSSNSGFGPEEDSSYLDGVSLPDFELLSDPEDEHLCANLMQLLQESLSQARLGSRRPARLLMPSQLVSQVGKELLRLAYSEPCGLRGALLDVCVEQGKSCHSVAQLALDPSLVPTFQLTLVLRLDSRLWPKIQGLLSSANSSLVPGYSQSLTLSTGFRVIKKKLYSSEQLLIEEC", "length": 231 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3IAH8-1", "protein_name": "Guanine nucleotide-binding protein subunit gamma", "gene_name": "LOC100755128", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MASNNTASIAQARKLVEQLKMEANIDRIKLSKAAADLMACCAAHAKEDPLLTPVPASENPFREKSFCTIL", "length": 70 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3IG76-1", "protein_name": "Olfactory receptor 7E24 isoform X2", "gene_name": "LOC100765597", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MYILALFGNLLIILTVSSDSHLHTPMYFFLSNLSMIDIGYISTTVPRVIVDIQTHCPVISYVGCLTQMSLIIIFACMDDMLLSVMAYDRFVAICHPLYYQVIMNPSSCGVLLLGSFLLSLVNLLLHYVAVLSFSNCEDIFEISNFFCGPSELFKLACFDTFTTNIVRYCAGALFGLLPISGIIFSYFKIVSSIMRSSSSSNGKWKTFSTCGSHLSIVCLFYGTALGMYFSSSLSLSPKTNAVASVMYTVVTPMLNPFIYSLRNKDIKTALRKILSRTF", "length": 278 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3IGD7-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100770882", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSGANSSSLTPEFFVLNGIPGLEDAHVWISLPFCFMYMIAVVGNCGLMYLIGHEEALHRPMYYFLTLLSFTDITLCTTTVPNTLCIFWFNLKKIGFKACLAQMFFVHTFTATESGMLMLMALDRYVAICYPLRYGTILTNPVIAKASLATFLRSVAFILPFTFLTKRLPYCRGNTIPHAYCDHMSVAKISCGNVKVNAIYGLLVALVVCAFDIFCITVSYTMILRAVMNLSSADARHKAFSTCTSHICAIVITYVPAFFNFFTHRFGGHTIPHHIHIIVANLYLLLPATMNPIVYGVKTKQIRESVIKFFSGDKSGITEIKGLQNK", "length": 326 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3INQ1-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100763177", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MFCNTSTPGHSTFLLTGFPGLEASHHWVSIPINLICVVSILGNSIILFLIRTDPALHEPMYIFLSMLAASDLGLCASTFPTMVRLFWLGIRELPFDLCAAQMFFIHAFTYVESGVLLAMAFDRFIAIRDPLHYATILPHSAVAKVGAAVLIRAILLNLPGPILLRRLLFPQVSVLSHCYCLHCDLVGLACSDTRINSLVGLVSILLSLGLDSSLIMLSYVLILRTVLSIASPGERLKALNTCVSHLCIVLIFYLPKLGLSVLHRVEKHSYPALAVLMANLHFLVPPFMNPVVYCIKSKQIRQGFLKRFQQKRVDVS", "length": 316 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3MYE2-1", "protein_name": "Large ribosomal subunit protein uL18", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGFVKVVKNKAYFKRYQVKFRRRQEGKTDYYARKRLVIQDKNKYNTPKYRMIICVTNRDIICQIAYARIEGDMIVCAAYAHELPKYGVKVGLTNYAVAYCTGLLLACRLLNRFGMDKIYEGQVEVTGDEYNVESIDGQPGALTCYLDAGLARTTTGNKFFGALKGAVDGGLSIPHSTKQFPGYDSESKEFSAEVHRKHIMGQNVADYMRYLTEDEDAYKKQFSQYIKNNVTPDMEEMYKKAHAAIRENPVYEKKPKKEVKKKRWNRPKMSLGQENDRVAQKKASFLRAQERAAES", "length": 295 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3MZM9-1", "protein_name": "Uncharacterized protein", "gene_name": "LOC107131211", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNLFIYVLLLSIWTSSCLDRNESNGSATAVTTRAEFKQTKLQELRRRLLIIVIGTLITGYMVTCTCLLHYRCDSKEAHKAAKDKKEDITIKASRSSKISFTDSKSPTAGLGDPERQSVVSRIDKSSGPSSPRKVPSSAEKLVRPSSQKKPSKPSAPKKVLGSPPQEKLHRTRSPKKAHRQAHAHKLVSQVSPSYPEKAIKPTWPPSLQCRVKPTKTPLPYPKNQSFPEHSSADKLTKRQRYLKLKCPASAGRAEILSRPQPVKFCRCYKEKCLVCRAVSEPFITHVSEANKKHVPVPLFSRELKHFYKSYKKKQPKYNTLYGNMSDSDITTYNSDGESDREVIIMCNIKCKEDIYKNSPNN", "length": 361 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3UW31-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r176", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSQNKSVKTTVEVTLQILLLCQVGVGTVVNIFLFVHNLSPFLNGSQQRPIKVILANLALGNTLILLFAFPNNIRVFIPREFPTDLKCKLGYFIWLVARSTNMCSTCSLSTYQFVTLAPGTWGRVMLPGRAPNFLRYTCYSCWLFSVLNNAHIPMKVSGPQKTHNDSNSKSKWVCSTSGFSIGMRILSFAHDAVFISIIIWSSVSMVILLNRHHQRLQHIQSTNQKLRVHAETRASHTILLLVVTFVTCYLLDCICTVCNISFVDSRVWLRRVKEILSVSFPTFSPLLLIFRDPKDPCSLLFGC", "length": 304 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "G3UY92-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r158", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQLLLLCQFGVGTVAKVFLFVRNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPTELKCKLESFSHLVARSTNLCSTCVLSFHQFVTLVPLNRGKGKLVLRASVTNMASYSSYSCWFFSVLSNIHIPIKVSGPQIKDNNTDSNRKLFCSTSGFSVGTVLLQFAYDATFMSIMVWASVSMVLLLHRHRQRMQHILTPNQDARGQAESRATRTILMLVVTFVSFYLLNFICIMLHALFMHSHFFVRLVSEILTAVFPSISPLLLIFRDPKDPCSVLFNC", "length": 307 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "G3V9M0-1", "protein_name": "Cystatin S like 1", "gene_name": "Cyssl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MACLLYTQLFLLNTFILFLNLSLNPVLGQILAGIEKSIIEEEGALEALNFAVSEYNENNSDLYLSRVVEVKTVKTVQQQIEAGKTLLFDVILGKTACLKTQDDLSDCPLNEPTDLQEREFCSFEVHLPDWANAINLLSSICNRI", "length": 144 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3X693-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "RVFLPLLLLGVILPGGDNEDGPTSFHLIQISTFVNNTWAQNQGSGWLDDLQIHGWESDSGTAIFLKPWSKGNFSDDEVTELVDLFRAYFIGFTREVQDRVNEFQLEYPFVIQVTAGCELHSGEAIESSLRGALGGLDFVSIQNHSCVPAPDGSSRGQKFCALTTQYQGISDIIERLLSETCPRYLLGVLDAGKAELQRQVKPEAWLSSGPTPGPGRLLLVCHVSGFYPKPVRVMWMRGEQEQPGTQQGDLMPIGEAAGLNCRVKHSSLGDQDIILYWGHPTSIGLILVAIIVPSLILLICLAFGVLRFMGSHRIGHD", "length": 317 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3X9Q9-1", "protein_name": "Predicted gene 6526", "gene_name": "Gm6526", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLRRLFHRENGDQGETRPRQKESAIPSCKKRRMKSFWGRHMSAGKKSSQNCNITNHMKNMNKLEDMKFYIRKINAKRLELFPILDIDMNTDLNYRMNIEFTIIKSQHEKTMLDMEKMTQSISDTIETYKEFIEDKDSYSFTHSYLLKECNQLKEKVRMLLNENRKLLVEQADQEASYGEEKRFCDESSKNIHPKC", "length": 198 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "G5E8X8-1", "protein_name": "Oocyte maturation, alpha", "gene_name": "Omt2a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDTLVFTKVHLESWVYKGLRGQHDSILELLKENLHHYLCIEFDEGLNDTVVYIIGFKFFAMFAMFVIVSLACNLRTKRNRARAWARGLQSPVWWNRRYFI", "length": 100 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "H3BJ46-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLSFMSSLLENILYFQAGLGVLANIFLLVFYIFIILGHRPKPMDLISCQLTFVHIMMFLAGENFWLANIFESLNVENDFKCKATFYTKRVMRGLSICITCLLSVFQAVMISHRNSLLAKFKHKLKIYMINALFYIWTFNLSLSSNLIFYVGGFTNMSQTKQLKVTKSCSLIPMNYIIRGLILTVISSRDMFLVGVMLTTSTYMVIILCRHQRQCKHLHSTSHLRASPEKRATQTILLLVVFFVIMYWVDFIISSTSILLWMYDPVIMIVQKFVVNAYPAITPFVQISSDTRVIRVVKNWHS", "length": 303 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "H3BJ88-1", "protein_name": "Vomeronasal 2, receptor 3", "gene_name": "Vmn2r3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMAIRKKCLILELTVFLCVELYAQYEDQNMTCRLMRKFNLTGYVEAENHHFVIGGQFPVHYRTIPTSDSDEEPESPMCEGFNFRGFRWMKTMIHTIKEINERKDILPEHTLGYQIFDNCFSTTKAMESSMVFLTGQDEYKPKWRNSTGKYLIGIIGAGGSTMSLAGARILLLNDVVQVGYASSSSILTEYLNVYRTIPSDKFQTEAIVNLIRHFGWVWIGAIASDDDYGKHGVKSFRKILETNNLCIAFSETIPKVYSNEKMQIAIDAVKSSTAKVIVLYATDFDLSPFVLEVIHHNIAHRTWIATEAWITSALIAKPEYFPYFGGTIGFAIPRSVIPGLKEFLYDVHPSKDPNDVLTIEFWQTAFNCTWPNSSVPYNVDHRVNMTGKEDRLYDMSDHLCTGKEKLKDLKNTYLDTSQLRITNNVRQAVYLMAYGLDRLIRVLIKEYREYLLHPKILAFMSYKLFEYIRKVKFTTHDGRKIELNVHGDIENGYYDILNWQMDNTGDIAIVKVGEYKFTRSKYELVLPKNSTLFWNTESSRLPDSVCTKVCPPGTRKGFITGQPVCCFDCIPCEDGYVSEKPGQRLCNPCSEDDWSNAEKNKCVPKHVEFLAYEEALGFTLVILSIFGALVVLAVTVVYVIHRHTPLVKANDRELSFLIQISLVITVLSTMLFIGKPCNWSCMARQVTLALGFCLCLSSILGKTISLFFAYRISISKTQLISMHPSFRKLIVLLCVFGEIGVCASYLVLKPPSMFKNIERQNVKIIFECNEGSVEFLCSIFGFDVLLALLCFVTTFMARQLPDNYYEGKCITFGMLFFFIVWISFVPAYLSTKGKFKVAVEIFAILASSYGLLGCLFLPKCFIILLRPKRNTDETVGGRVPTVDRSIQLTSASVSSELNSTMVSTVLDE", "length": 909 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "H3BKT1-1", "protein_name": "piRNA-mediated silencing protein C19orf84 homolog", "gene_name": "Gm52993", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDELEDGALSNGDNLSLPSAGTESWPTSATPGLPPSLLSTLDPTHLGLPEQLASVTVPIRLDTLSYLLHSALLGTYNLQQSLPPCSCTAQPSHIWPDTVRRPPRRSGQARGGWEVRRRPSRGWGRGRGRGRVWAQSQRGPERAEERERNMAGEPGAGPSTPPVTPPSQDGQKEAGGLSEDWEADY", "length": 185 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "H3BLP0-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLTNILYFQAGLGILANTFLLCFYTFTILCHRSKPMDLTSCQLTLAHILFLLAGGDNWLAVILESLNIENDFKCKAIFYTNRVMRGFSICITCLLSVFQAVTISPHTSLLAKFKHKLKTYIIYAVFYIWFYNFLVCSHLLVYVGGFNNVSETNQMRVTESCSLFLMNYIISGLIFTVTTFRDVFLVGVMLITNAYIVIILFRHQRHCKHLHSIRHLRVSPEKRATQTILLLMVFFVVMYWVEIIISSTSLLLWMYDPGFLTVQKLIVTVYPTITPLVQISSDKRVINVLKNLQSKCQQIF", "length": 302 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "I3ITL1-1", "protein_name": "Gap junction protein", "gene_name": "gjc4a.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSWDFLTHLLDEISNHSTFVGKIWLTLLIVFRIVLTVVGGETIYDDEQSEFVCNTLQPGCKNVCYDAFAPLSHVRFWVFQIIMISTPSVMYLGFAMHKIARMADNEYQPRKHKMLSTVHQRMNRDYDMVDEMTEEVPMIPEEIEPSEKDNKSAASTKTTAASDAAVKHDGRRRIKRDGLMKVYVLQLISRVAFEIAFLFGQCILYGFEVSPSYICTRSPCPHTVDCFVSRPTEKTIFLLIMYVVSVLCLALTVLEILHLGIGGLRDSFRSRANRRLPVHRPSTSTICHRLSSAPPGYQAVQKKYSSGKLKAEFLSDSGRESLADDNTTRDLDRLRRHLKIAQQHLDQAYHTEEVGASHNSGPDSKSIAAEQNRLNQAQGGFGSTEEKVFKEAHA", "length": 394 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "I3L8A5-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "FPSRQERTMRRENQSSISEFLLLGLPIPPEQQGVFFALFLGMYLTTMLGNLLIILLIRLDPRLHTPMYFFLSHLALTDISFSSVTVPKMLMNMQTQDQSIPYAGCVTQMYFFMFFACLDNFLLTSMAYDRYVAICHPLRYTSIMRGGLCTLLVTVSWILSCANALCHTLLLAQLSICAENTIPNFFCDLGALLKLSCSDTSFNDLAIFIAGVATIMLPLLCILVSYGHIGATILKIPSTKGICKALSTCGSHLSVVFLYYGTIIGLYLVPSSSTSSHKDIVASVMYTVVTPLLNPFIYTLRNRDMKGALEKLFHKAPVLS", "length": 320 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "I3L8Z8-1", "protein_name": "LRRC37A/B like protein 1 C-terminal domain-containing protein", "gene_name": "LOC100514982", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MMTLELEKLILPSHMACCLCQFKSNIEVVCKTVKLHCDRCLKNSTRCDKETSLGDVEGSFMKVLQARKKNTSTELMIEPERPSSDKSGVSLSSFMNEQLDFSDESDVISALNYILPYFSEGNLEDVESTLLPFIQLLFSNVAEADIPPGHLKTHTGNPPVNPESGTSGYTNKLRQLRFLENLLDAEIQEKIDEVMKKEKTAMLIYSNILSPKLRRQILRKKLETARTQAESLEEIESVDKRPLKVNRVLKGPRGIKKRHFRAMRRQSIRRKETAQPFVETTTKGSKLGGPSARELEQLWVVQRPRKRVADSLQKEPSFGREHKAEVSSFLKQYSRGRPAASIHPKAPATVKKTSEDLSDTLFVLVDANARVKNRKASETISYPRKIDSFHPSHSPVLHRTPEPQNRQAFRDKGSSYRLLLALRPLSSAVRSLINSPSQEASSPSGELTLQEQPSPESFSPSEPSTEHIISEKDTPQVVFEELPTSGTTTLSGPIPGPTAQGTLPTEYSATTADNVMPTGQHTSAIQWEHHNVGTDVASTPTSFISPGVSSPGSQFEAQLNQQLQSLIPNNDVRRLISHVIRTLKMDCSEPQVQLACAKLISRTGLLMKLLSEQQEAKASKAEWDTDQWKTENYINENTEAQGEQKESSELTKDVPGYGYNNKLILAISVAVVLMLLIVILCLIEVYSRRRTLREGKVGRRRGFFGFLLRKRRSGESESEGFFWRRRPLWLRDTYRPLSATRKKNMAEKLHDKESSDEEEIFHKGAGEVSEAPADVILTIESDVEDLGEETDTAPEGPPE", "length": 799 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "I3LBH4-1", "protein_name": "Large ribosomal subunit protein uL11", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPPKFNPNEIKAMYLRCTSGEISAKSALAPKIGPLGLSPKEVGDDIAKAAGDWKGLRITVKPTIQNRQAQMEVVPSASALIIKAPKELPRDRKKQKNIKHSGNITFDEIVNIARQMRRCSLARELSGTIKEILGTAQSVGCNVNGRRPHDIIDDISSGAVECQAS", "length": 165 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "I3LC12-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MFGANLTIFHPTVFILLGMPGLEIYHTWLSIPFCLMSIVAVLGIGALILVVLSESTLHEPMHVFLSMLAGTDNLLSTTTVPKALAIFWFHAGEIAFDACITQMFFIHVAFVAELGILLAMAFDRYVAICALLRYTAVLTPSTIVKLTLAIWGWGIGTIFPIIFLLKRLPYCRTNIIPHSYCEHIGVARLACADITVNIWYGFSVPMASVLVDVAFIAVSYTLILQAVFRLPSQDAQHKALNTCGSHIGVILLFFIPSFFTFLTHRFGKNIPHHIHILLANLYVLIPPMLNPIIYGAKTKQIRDSLAHMLSRVGMS", "length": 315 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "I3LEQ2-1", "protein_name": "All-trans retinoic acid induced differentiation factor", "gene_name": "ATRAID", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MARPGFRSPSSLVPRAAALLLVLSVPRALALPEICIQCPGDVQNLSEVALYCKQTPELMLQGRCCLNGKGTILGLDLQNCSLKDPGPDFAQAHTAVIIDLQANPFEGDWANTFRGFTQLQTLILPQGVNCPGGINAWDVVTFYITNQTCQGQRTFATALGTQKRVLRMDLVLLMVLVSCSVFVLMASMATSVCARAHSHCSCSSVFWDPQHYPFPSCFGGLNAEKPRLHEPQRSSY", "length": 236 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "J3QM75-1", "protein_name": "Secretoglobin, family 2B, member 19", "gene_name": "Scgb2b19", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLGLLITGELSFQTTEACVPFFEGYASVVSGSRVWLYHELQSFDATAEEKVALEKIQGCYREERLRNILLEPKIMEAMVASPECRSYYSLNNFRSILDFISNLLGE", "length": 112 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QMG8-1", "protein_name": "T cell receptor alpha variable 13N-3", "gene_name": "Trav13n-3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKRLLCSLLGLLCTQVCWVKGQQVQQSPPASLVLQEGENAELQCTYSTTLNSMQWFYQRPGGRLVSLLYSPSWAEQRGGRLTSSAASNESRSSLHISSSQITDSGTYLCAME", "length": 112 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QML3-1", "protein_name": "BTB domain containing 35, family member 29", "gene_name": "Btbd35f29", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHQGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKKVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIIWDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYNEEQIVMKLDSDALTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QMQ9-1", "protein_name": "Predicted gene, 20873", "gene_name": "Gm20873", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLMKKRRRESSSNTLRNIVGRRISHSWKEGNEPVTQWKAIVLDQLPTNPSLYLVKYDGIDSIYGLELYSDDRILNLKVLPPIVVFPQVRDAHLARALVGRAVQHKFEGKDGSEVNWRGVVLAQVPIMKDLFYITYKKDPGLYAYQLLDDYKEGNLHMIPDTPPAEERSGDDSDVLIGNWVEYTRKDGSKKFGKVVYQVLANLSVYFIKFHGDIHIYVYTMVPKILEVEKS", "length": 232 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QMS5-1", "protein_name": "BTB domain containing 35, family member 2", "gene_name": "Btbd35f2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLSCRDSSLLEPQPEDIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKKVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QMW5-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad17", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRRRGKNENESEKRELVFKEYGQEYAQVTKMLGCGWLEAMCFDGVRRLCHIRGKLRKKVWINTSDIILIGLRDYQDNKADIILKYSPDEARSLKAYGELPEHAKINEMDTFGAGDDDEIMFDDIGEDDEDIDDI", "length": 144 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QMW9-1", "protein_name": "BTB domain containing 35, family member 6", "gene_name": "Btbd35f6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLSCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYRDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLQTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QN64-1", "protein_name": "BTB domain containing 35, family member 22", "gene_name": "Btbd35f22", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDMKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYIDNISFLESEEGLIFQPVFKKLRFQHIIWDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYNEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QNQ5-1", "protein_name": "BTB domain containing 35, family member 24", "gene_name": "Btbd35f24", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEGIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKDTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIIYDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QP08-1", "protein_name": "Histone H2A", "gene_name": "H2al1k", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAKKMQRRRRQKRTRSQRGELPLSLVDRFLREEFHSSRLSSSALSFLTSVLEYLTSNILELAGEVAHTTGRKRIAPEDVRLVVQNNEQLRQLFKPGGTSVNEDDN", "length": 105 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QP87-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRRRGKNENESEKRELVFKEYGQEYAQVTKMLGCGRLEAMCFDGVRRLCNIRGKLRKKVWINTSDIILIGLRDYQDNKADVILKYNQDEARSLKAYGELPEHAKINETDTFGAGDDDEIVFDDIGDEDEDIDDI", "length": 144 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QP96-1", "protein_name": "PRAME like 3C", "gene_name": "Pramel3b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMDTKDPPTLLDLATQSLLSNEHAAIQALEEIPRELFVPLFTAAFTGRHKNILTAIVKAWPFACLHIGALSVQEPERELLKALIESLQFLPALNSATRSPKLRILDLRQDAGCKTVCPDISTNSTICFRSCAHSEHSIFKIEGQESLSSSKSEAQPSRLPMELIVDISLDGTLRERNFFALLQNKVEQSLGSLHLCCRDLQINNLCECRHALSHLDLKCVDHLAVDESPLTEVTKLLSHTIQLDSLSLSKIACRSLNGRTFRNFITQLSRMNHLKELSLSSFCLTDHLETVLRVLSADLEFLYLPFCGLSYSDFKFLSECSQVSHLKLLNVNNNPIYWEDCEPFYYLLQNVSSTLQHLKICYCFLTDSTISVLIPALTRCSQLRVLHFYSNQITMGMLMRILELLTPLKELKHVIYPIPVHCYGRWHFQGSLDRQKVEDVQRQLNLMLQEAERSDMNWITYSD", "length": 463 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QPI8-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad16", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRRRGKNENESEKRELVFKEYGQEYAQVTKMLGCGWLEAMCFDGVRRLCHIRGKLTKKVWINTSDIILIGLRDYQDNKADVILKYNPDEARSLKAYGELPEHAKINEMDTFGAGDDDQIVFDDIGEDDEDIDDI", "length": 144 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QQ02-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRRRGKNENESEKRELVFKEYGQEYAQVTKMLGCGRLESMCFDGVRRLCHIRGKLRKKVWINTSDIILIGLRDYQDNKADVILKYNPDEARSLKAYGELPEHAKINEMDTFGPGDDDEIVFDDIGDDDEDIDDI", "length": 144 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7GP63-1", "protein_name": "Large ribosomal subunit protein eL39", "gene_name": "RPL39", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSSHKTFRIKRFLAKKQKQNRPIPQWIRMKTGNKIRYNSKRRHWRRTKLGL", "length": 51 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "K7N5V5-1", "protein_name": "Predicted gene 5862", "gene_name": "Gm5862", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRVNVDGRETREGRKDADLPSERNEGRRRWTWRMCMAHRQTTSPVPVKSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTYLHDLEMKNMEARENNQELKKEKNFYRNLHTRILLEENLIKKKLVILQQESKEVHADWATIHQSLVELNLSGKDEQEKTSNLETQEHQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPPSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N660-1", "protein_name": "Predicted gene 10220", "gene_name": "Gm10220", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRVNVDGRETREGRKDADLPSERNEGRRRWTWRMCMAHRQTTSPVPVKSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTYLHDLEMKNMEARENNQELKKEKNFYRNLHTRILLGENLIKKKLAILQQESKEIHADWAIIQQRLVELNLSGKDEQEKTSNLEAQENQVSEAARKLGLATAEEDSILQNELPCQEAPAEHHPQHPPSSSDESSSDESSYSTCPSWE", "length": 267 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6B6-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r168", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSQNGAMKTTEEVALQIVLLCQFGIGTMANILLFVHNFSPLLTGCQLRPKEVICANMAVSSILILFMTVFPNNVFVAQRNLLNDLQCKLEYFVYMVARSTNLCSTCVLSTYQFVTLVPGNFSELMVRGRSPKVISYSCCSCWLFGILYNVYIPMKVSGPQNRHNKTSTKSKWVCFTSGFSVGIVFLSFAHDAIFISIMVWASVSMVRLLYRHYQRLQYIFPPHQGNRGYAEIRAAHSIVLLVVTFVSFYLLHCICFILHIVFVDSNLWLRHIGEVLTSSFPTISPLLLIFRDPSYPCSLIFNYKKPVI", "length": 309 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6B7-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Gm10670", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVRGKSLKTTEEVALQIILLCQFGVGTMANDFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTVFPNNMMAFAPRNPPTELKCKLKFFSHLVTRSTNLCSTCVLSMHQFVTLVPISRGKLLLRASVPNLVSYSCYGCWFFSVLSNIHIPIKVTGPQITDNNTDSKSKFFCSTSGFTVRIVFLQFSHDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQNPRGQAESRATNTILMLVVTFVSFYLLNFICIIFHTFFIHYNLFIRLLGEILAAGFPTISPLLLIFRDPKNPCLELFHCFKPESLQNLKHRRQLH", "length": 321 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6G6-1", "protein_name": "Predicted gene 16440", "gene_name": "Gm16440", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLRRLCQKENGDEGEIRTTEKEEGILSHEKGRRKSFWRRHRSARNTSTQNSKITKQRSKINELEELKLDMRKISNDMEEMGGILELYIYEDLNYRMNTEFNIIKSQHEKTMLDMNEMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLSEKVRILLNENRKLLVEQAGTQLSHEEEKRFCEEASKNICASSAKEQQCVNSSRNRNMAQTTT", "length": 218 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6J5-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r127", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQLLLLCQFGVGTLANVFLFVHNFSPVLTGSKQRPRQVILSHMAMANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVLVNRGKLILRASVPNFVSYSCYSCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVFLQFAYDATFMSIMVWTSVSMILLLHRHRQRMQHILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNFICIIFHTLLMHSHLFIRLVSEVLTAVFPSICPLLLIFRDPKDPCSVLFNC", "length": 305 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6P1-1", "protein_name": "Reproductive homeobox 2H", "gene_name": "Rhox2h", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEKRSINYLLDVGPEEDEENANGVKTLMVLLAGEGRNEGESGRGLPGSGVSAAEGYRAGELSAGGPAAPVAGLMDNSNQEDLSATGCAQEKETQPEEPVPDSMGDLENVKPMSGPWSTVNPVRVLVPKFRHLWRHNFNVLQLQELESIFQCNHYISTTEENRLARSMGVSEATVQEWFLKRREKYRSYKRL", "length": 191 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6T9-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r175", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLLQNKSVKTTEEVALQVLLLCQVGFGTAVNIFLIVHNLSPILNGSQQRPIKVILANLAVGNTLILLFAFPNNMTLFVPKDPPTDLKCKLGYFIWLVARSTNMCSTCFLSTYQLVTLAPGTWGRVMLRGRAPKFVRYICYSCWLFSVLNNAHIPMKVNGPQKTHNDTNTKNKWVCSTTGFSIGMRILSFAHDAVFISIIIWSSVSMVILLNRHHQRLQHIQSTNQKLRVHAETRASHTILLLVVTFVTCYLLDCICTVCNISFLDSRVWLRRVKQILDVSFPTFSPLLLIFRDPKDPCSLLFCC", "length": 304 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6U2-1", "protein_name": "Predicted gene 3542", "gene_name": "Gm3542", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSRLLRLCQKENGDEGETRPKKKEEGILSHEKGRRKSFWRRHRSARNTSTQNSNITNQISNINKVEELKLHIRKTSNERKEMCGILNVYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLNEKVRILLNENRKLLVEQAGTQVSCEEERGSLRRPARTSVPQVQRNSSFPKCETVQQKLEHGTDHDMISLKEKCWWKRTGCAQEIHHCCLSSLITMAVMGCMLLLYFGFLGMNRP", "length": 270 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6W5-1", "protein_name": "Predicted gene 17019", "gene_name": "Gm17019", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRANVDGRDTREGRKDADLPSERNEGRRRWTWRMWMALRQTSSPVPVISKKQFEKEEKKLIKEIQLTTEETNELRDRLIYVTEGSMNKRPYHRQNPLYEKLKLKEKEIMTFLHNLEMENMEAQENKQELKKETHFYRNLHSRLLMEENLIKKKSMTLQQESKEVQADWAIIHQRLVELNLSVKDEQENSNLETPEYQVSEAARELGLATAEEDSILQNELPGQEAPAEHHLQHPQSSSDESSSI", "length": 255 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6W9-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r170", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLLQNKSVKTTEEVALQVLLLCQVGVGTAVNIFLIVHNLSPNLNGSQQRPIKVILANLAVGNTLILLFAFPNNMTLFVPKDPPTDLKCKLGYFIWLVARSTNMCSTCSLSTYQLVTLAPGTWGRVMLRGRAPKFVRYICYSCWLFSVLNNAHIPMKVSGPQKTHNDTNTKNKWVCSTTGFSIGMRILSFAHDAVFISIIIWSSVSMVILLNRHHHRLQHIQSTNQKLRVHAESRASHTILMLVVTFVTCYHLDCICTFCNISFLDSQLWLRRVKQILDASFPTFSPLLLIFRDPKDPCSLLFCC", "length": 304 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6X3-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r94", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQLLLLCQFGVGTLANVFLFVHNFSPVLTGSKQRPRQVILSHMAMANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVLVNRGKLILRASVPKFVSYSCYSCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVFLQFAYDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQDARGQAETRATHTILMLVVIFVSFYLLNFICIIFHTLLMHSHLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFNC", "length": 305 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6X7-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r103", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQLLLLCQFGVGTLANVFLFVHNFYPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIYQFVTLVLVNRGKLILRASVPNFVSYSCYSCWFFSVLSNIHISIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVSLQFAYDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQYRRGQAETRATRTILMLVVTFVSFYLLNFICIIFHTLLMHSHLFIRLVSEVLAAVFPSISPLLLIFRGPKDPCSVLFNC", "length": 305 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6Y3-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r115", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQLLLLCQFGVGTLANVFLFVHNFSPVLTGSKQRPRQVILSHMAMANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVLVNRGKLILRASVPKFVSYSCYSCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVFLQFAYDATFMSIMVWTSVSIILLLHRHRQRMQHILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNCICIIFHAFYIHSRLFIRLVSEVLAAVFPSICLHNGVLLSY", "length": 295 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6Z0-1", "protein_name": "Predicted gene 17026", "gene_name": "Gm17026", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "XRSSWVPKQACCPCSSGYFRERIEYTQTPDQGRRRPAAHHGGKGQETTGHGEGSAGAASPQAPTINDQEKRHERLEKLKRELQNIKNARDELQGILANYTNKDLNDRINFETFMLQMQHDQVMTDLKRMPQDISEALYKCKQLTKENQFYCFRNCHLLIESNLIQHKVRMLRKENRQLLREQIALEECNIETKILCKEGSQKIKDHYTKQQQI", "length": 213 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N701-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r159", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQLLLLCQFGVGTLANVFLFVHNFYPVLTGSKQRPRQVILSHMSVANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVLVNRGKLILRASVPNLVSYSCYGCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVFLQFAYDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQNTRGQAESKATRTILMLVFTFVSFYLLNFICIIFHTLLMHSHFFIRLVSEVLAAVFPSISPFLLIFRDPKDPCSVLFNC", "length": 305 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N708-1", "protein_name": "Predicted gene 10128", "gene_name": "Gm10340", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLLRLFQKENGDEGETRPTEKEEGILSHEKGRRKWLWRRHRSARNTSTQNSKMTKKRSKRNELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLHENVRILLNENRRLLVEQAGHKCPVGKKRGSLRRPARTSVSQVPRNTSVI", "length": 205 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N731-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r57", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEVLALNILLLCHVVVGTVGNILLFVHNFSPNLTDSRLRPIQVILINLAVANAFMLLFSTYSYDLIDFVPRKPPTDLKCKLAYFFHMVARGTIMCSTCVLSTYQFVTLVPGNWARVMFREISPKVVSYSCFSCWLFSVLNNAYIPMNVSGPQKSHNDSDSKDNWICSISGVSVDMNFLRFSHDIIFLGIMAWTSVSMVIHLNRHHQRMNHIHKVNQNNRGHAETRAAHTILMLVVTFVSLYILNCIIILFHITFVESRLSLRHVTKLLSLSFPTISPLLLIFREPRGHCSLLFSVGLEIHVTGGVITEEQ", "length": 310 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N744-1", "protein_name": "Predicted gene 8104", "gene_name": "Gm8104", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLRRLFHRENGNQGETRPRQKESAIPSCKNRRMKSFWGRHMSAGKTSSQNCNITNHMKNMNKLDDMKFYIRKINAERLELFRILDIDMNTDLNYRMNIDFTIIKSQHEKTMLDMEKMTQSISDTIEKYKEFIEDKDSYSFTHTYLLKECNQLKEKVRMLLNENRKLLVEQADQETSYGEEKRFCDETSKNIHPKC", "length": 198 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N751-1", "protein_name": "Predicted gene 3696", "gene_name": "Gm3696", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLLRLFQKENGDEGETRPKKKEEGILSHEKGRRKWLWRRHRSARNTSTQNSKMTKKRSKRNELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLNENVRILLNENRRLLVEQAGHKCPVGKKRGSLRRPQEHLCPKCQGTAV", "length": 203 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N757-1", "protein_name": "Predicted gene 3667", "gene_name": "Gm3667", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLLRLFQKENGDEGETRPTEKEEGILSHEKGRRKSFWRRHRSARNTSTQNSKMTKKRSKINELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLNEKVRILLNENRRLLVEQAGHKCPVGKKRGSLRKPARTSVSQVPRNSSVK", "length": 205 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K9J7F4-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r260", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGNSLKTTEEVALQILLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPTELKCKLESFSHLVVRSTNLCSTCVLSVHQFVTLVPLNRGKGKLVLRASVTNMASYSSCSCWFFSVLSNIHIPIKFSGPQITDNNTDSKRKLFCSTSGFSVGIVFLQFAYDATFMSIMVWTSVSMVLLLRRHRQRMQHILTPNQNPRGQAESKATHTILMLVFTFVSFYLLNCICIIVHALFMHSHFFVRLVSEILTAIFPSISPLLLIFRDPKDPCSVLFNC", "length": 307 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K9J7G0-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r163", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFVHNFSPVMTGSKKRPRQVILSHMAVANALTLFLTIFPNNMSAFAPKTPPTELKCKLEFFSHMVARSKNLCSTCVLSIHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLKFSHDATFMTIMVWTSVSMVLLLHRHHQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPNICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K9J7G4-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r242", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVHDKSVKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPNELKCKLESFSRLVARSTNLCSTCVLSIHQFVTLFPVSRGKGKLILRASVQNLASYSCYSCWFFSVLSNIHIPIRVTGPQITDNNTDSKSNLFCSTSGFIVGIVLQFAHDATFMSIMIWTSVSMILLLHRHCQRMQDILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNCICIIFHAFFIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSLLFKC", "length": 306 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K9J7H2-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r256", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSLKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILGHMAVANALTLFLTIFPNNMMAFAPKTPPNELKCKLESFSLLVARSTNLCSTCVLSIHQFFTLFPVSRGKGKLILRASVQNLASYSFYSCWFFSVLSNIHIPIRVTGPQITDNNTDSKSNLFCSTSGFIVGIVLQFAHDDTFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQNPRGQAESRATHTILMLVFTFVSFYLLNCICIIFHAFSIHSCLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 306 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K9JA28-1", "protein_name": "Interferon lambda receptor 1", "gene_name": "IFNLR1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSAWRIRVLATLCFLWQPRVHGQLPPPQNVTLLSKDFDMILTWTPGEGSPPDVLYTVRYESKTRMDKWIKVPHCRNIHSVSCNLTCVIPNFFIKFRAQVKATSGRFHSPWVKSQFKEYHLDVELAPPLLNVNVKENVIHVNATFPMAICVESLPWMYDFNLWEAGSEDKKQYKSIFRKKAVTIDTTALRGNYCFNARSSIQSIDFKHSKFSQPVCMQLNYEGEWKFPFSATIPVFVLLILLTSASIIWLLKQDAKHKKMPQTLDLSNCKIAGPTFCCELRENEFLTDCLICTDKPMSQGKKNKTLAQNNQMWMASFLPSSSSEEEEEEEEEDSSSFIPYTEMLQFPRKHFNFQTPRTADAETILDSTSGVLSVVGGSTLDLSALGFSFFPIRKNEMDTSGSQGNEKASHSHSSSLGRISLTDVRFPGPREHGQHGTDSNDCLEVSLLHTLMNSSCTRLPADEHCLYKKDHDFTICYQKPTLDQPVQVSENPLLNEDPSMEKFIYLQTLQVAEDEGFASDCDSGNFTEGTPPASTVLSDELRISDMEKRYDKKFKFKGYQHSHYMRRS", "length": 567 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "L7MU37-1", "protein_name": "Reproductive homeobox 3H", "gene_name": "Rhox3h", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSMKPERSISNWIHSNVEPAGRNLFQVNGHRSALLPELPQDYHRASRSVNGCETKMDSTQGTKVLPAEESRNEEDGGQVESALGATAARGRGKEALNGESPAAAGTAGLVEEDRNKEDGGTKGGEKNEQEVREQIPEHVEGESDQAEAPRQVPRRRLHHRFTQWQLDELERIFRMNYFLSLEARKQLARWMGVNEAIVKRWFQKRREQYRWYKRL", "length": 215 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7MU51-1", "protein_name": "Olfactory receptor", "gene_name": "Or4a76", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGQSNNVTEFVLLGFTQDPAGQKALSVMFSLIYIVTMVGNLLIVGTVIASPSLGSPMYFFLASLSLMDAIYSTAITPKLIVDLLCEKKTISFRACISQLFIDHLFGGVDIVILLAMAYDRYVAICKPLHYLIIMNRRVCILFLVMAWAGGLAHALFQVLAVYNFPFCGPNIIDHFGCDIYPLLLLACTDTYFLGLSIIGNNGAMCIVIFTLLLLSYGIILRFLKNHSQEGRRKALSTCGSHITVVFLFFVPCIFMYVRPVSSFPIDKFITVIYTIVTPMLNPLIYTLRNSEMKNSMEKLLQKTLSPSRIRLSSCCLCY", "length": 318 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7MU81-1", "protein_name": "BTB domain containing 35, family member 17", "gene_name": "Btbd35f17", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANTWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7MU83-1", "protein_name": "BTB domain containing 35, family member 18", "gene_name": "Btbd35f18", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDQVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7MUB9-1", "protein_name": "Reproductive homeobox 2G", "gene_name": "Rhox2g", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MERQSINYKLDVGPEEDEENANGIKTLMVLLAGEGRNEGESGRGLPGSGVSAAEGYRAGELSAGGLAAPVADLMDNNNQEDLGATGCAQEKEKQPEEPVPDSMGDLENVKPMSGPWSTVNPVRVLVPEFLHGWQQSFNVLQLQELESIFQCNHYISTTEAKCLARSMGVSKATVQEWFLKRREKYRSYKRL", "length": 191 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N1X6-1", "protein_name": "F-box/WD repeat-containing protein 15", "gene_name": "Fbxw15", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAIHLPCLPMMKILSYLDAYSLLQAAQVNKDWNELASSDVLWRKLCQKRWLYCDMDTLQLQGKETWKQFFIDRIWQERAKFRAKAKDFTYKEIPLMCGLFGYACYISGCGLTRKGQDKSVVCMVNSKNTISTWDVHKSVITWKSPEQPASIKLLTTLPEMHIAVTVDIQSTIKLWDCHNREALATNNLKSPCKSLKAVFTKDGPIVLIGDTLGNIHIFRIPDLYLISTVNVLPYGFDGIYCSPQKKWVLLSKKHPHILPKVFYMSSFLRTSEFSAPVSTVLKLSLYERVFWTPRREDRITLMSRSGFPQVKMFETYDIKLEEFGNKRIVKGKLIASFELQCHKVNPQRFGVSDKNVIVCSTESSLLLFDINGLRLKTFQYCPEMIVKLSVDPLHVIVICNTGSMDVYAWEERSLLLRKCYRLHIERPLPLYGFIYKAACDDVSIIQLITDELSLSSLTSYALNICS", "length": 466 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N1X9-1", "protein_name": "Demilune cell and parotid protein 1", "gene_name": "Dcpp1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFQLEAMLALLILAFLGTPTVLTQDYHGPEVGKHSCTSAPEGKNITSIRVFLKGRLIVGIQLNYDDNKDGQVYGSTAGKEMVARLSKEEHIIAAQGTYTPSALTQIIFTTNQPRQLMVGYYVGNSEYSSFPNDPSHVLKGACVSWRAGGIKSILFLWGSENSSCVKYGHSG", "length": 171 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N1Y3-1", "protein_name": "PRAME like 51", "gene_name": "Pramel51", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIHSKERKYRLGLLEPGVTAFPCPNMVICLHCPDQDDSLEEVTEECYSPPTLQNLAIQSLLRDEALAISALTDLPQSLFPVIFEEAFTDGHIGILKAMIPVWPFPYLSLGKQINNCNLETLKAMLEGLDILLAQKVQTSRCKLRVINWREDDLKIWAGSHEGEGLPDFRTEKQPIENSPGCEVKKELKVTTEVLRMKGRLDESTTYLLQWAQQRKDSIHLFCRKLLIEGLTKASVIEIFKTVHADCIQELILRCICIEELAFLNPYLKLMKSLFTLTLDHIIGTFTLGDSEKLDEETIFSLISQLPTLHCLQKLYINDVPFIKGNLKEYLRCLKKPLETLCISNCDLSQSDLDCLPFCLNICELKHLHISDIYLCDLLLEPLGFLLERVGDTLKTLELVSCCIVDFQFSALLPALSQCSHLREVTFYDNDVSLPFLKQLLHHTALLSQLIYECYPAPIECYDDSGVILTHRLESFCPELLDILRAKRQLHSVSFQTTKCSKCGGCYIYDRHTQCCRFVEL", "length": 520 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N1Y5-1", "protein_name": "Olfactory receptor", "gene_name": "Or11g25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTLSSPSNSSTITGFILLGFAYPREGQILLFVIFFIVYILILMGNASIICAVYCDQRLHTPMYLLLANFSFMEIGYVTSTVPNMLANFLSDTKVISFSGCFLQFYFFFSFGSTECFFLAVMAFDRYLAICRPLHYSSLMTGRLRNTLVTSCWVLGFLWFPVPIIIISQMSFCGSRIIDHFLCDPGPLLALACSRVPLIEVFWSIIMSMLLVIPFLFIMGTYILVLRAVFRLPSREGQKKAFSTCGSHLTVVSLFYCSVMIMYLSPTSEHEAGMQKLVTLFYSVGTPLLNPMIYSLRNKDMKNALQKILRT", "length": 311 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N227-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r125", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSMKTTEEVALQIILLCQFGIGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMSAFARKTPPTELKCKLEFFSHMVARSTNLCSTCVLSVHQFVTLVPVNRGKGKLILRASVPNFANYSCYSCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLQFSHDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N255-1", "protein_name": "Predicted gene 3099", "gene_name": "Gm3099", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSRLLRLCLKGNGDEGETRPKKKEEGILSHEKGRRKLFWRRHRSARNTSTQNSNITNQISNINEVEELKLHIRKISNERKEMCEILNVYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMTQFIIGSMQYSMELIEDNYSYSIKEDHLLRECTQLNKKVRILLNENRKLLVEQAGTQVSCGEEKRFCEEASKNICASSAKEQQLP", "length": 205 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N259-1", "protein_name": "Demilune cell and parotid protein 3", "gene_name": "Dcpp3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFQLEAMLALLILAFLGTPTVLTQDYHGPEVGKHSCTSTPEEKNITSIRVFLQARSIVGIQFNYDDKDGQVYGSTAGKEMVARLSKEEHITGVEGSYSPSALTQIVFTTTQPRQLMVGYHVGIYQYSSYPDDPSFVLKGACVSWRAGGIKSILFLWGSENSSCVKYGHSG", "length": 170 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N270-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r123", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSLKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILIHMAVANALTLFLTIFPNNMSAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVPVNRGKGKLILRASIPNLWNYSCYNCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLQFAYDATFMIIMVWTSVSMVLLLHRHRQRMQHILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNFICIIFHAFSIHSHLFIRLVSVVLAAVFPSICPLLLIFRDPKDPCSVIFKC", "length": 307 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N273-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r118", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVHDKSVKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPNELKCKLESFSRLVARSTNLCSTCVLSVHQFVTLFPVSRGKGKLILRASVQNLASYSCYSCWFFSVLSNIHIPIRVTGPQITDNNTDSKSNLFCSTSGFIVGIVLQFAHDATFMSIMIWTSVSMILLLHRHCQRMQDILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNCICIIFHAFFIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSLLFKC", "length": 306 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N275-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r169", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSQNKSVKTTVEVALQILLLCQVGVGTVVNIFLFVHNLSPFLNGSQQRPIKVILANLALGNTLILLFAFPNNIRVFIPREFPTDLKCKLGYFIWLVARSTNMCSTCSLSTYQLVTLAPGTWGRVMLHGRAPKFVRYTCYSCWLFSVLNNAHIPMKVSGPQKTHNDTNTKSKWVCSTTGFSIGMRILSFAHDAVFISIIIWSSVSMVILLNRHHQRLQHIQSPNQKLRFHAETRAAHTILMLVVTFVTCYLLDCICTSLHISFVDSRVWLRRVKEILAVSFPTFSPLLLIFRDPKDPCSLPFSC", "length": 304 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N288-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r151", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQILLLCQFGVGTLANVFLFVHNFYPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIYQFVTLVLVNRGKLILRASVPNFVSYSCYSCWFFSVLSNIHISIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVSLQFAYDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQYRRGQAETRATRTILMLVVTFVSFYLLNFICIIFHTLLMHSHLFIRLVSEVLAAVFPSISPLLLIFRGPKDPCSVLFNC", "length": 305 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N2A6-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r116", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFFHNFSPVLTGSKQRPRQVFLSHMAVANALTLFLTIFPNNMSAFAPKTPPNELKCKLEFFSHMVARSKNLCSTCVLSIHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLQFSHDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N2B4-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r128", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFVHNFSPVLTGSKKRPRQVILSHMAVANALTLFLTIFPNNMSAFAPKTPPTELKCKLEFFSHMVARSKNLCSTCVLSIHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLQFSHDATFMTIMVWTSVSMVLLLHRHHQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLGAVFPNICPLLLIFRDPKDPFSVLFKC", "length": 307 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N2C2-1", "protein_name": "Predicted gene 2974", "gene_name": "Gm2974", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLLRLFQKENGDEGETRPTEKEEGILSHEKERRKWFWRRHRSARNTSTQNSKMTKKRSKINELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLNENVRILLNENRRLLVEQAGHKCPVGKKRGSLRRPARTSVSQVPRNSSVI", "length": 205 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N474-1", "protein_name": "Spermatogenesis associated glutamate (E)-rich protein 1E", "gene_name": "Speer1e", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "ARRHTSSTAPDLSKKEFKKEKERLTTELHLLIQLRNEQRDHLIDFKESSNYNRTKPTQKKNPFYEQLRSTKNQVLSSVHKLEMGIIEAQENIQELNKWIDYFTNLHSQLLMEKNLKMSITQNQKNKEVEIDWALIEKYLVDVNLNGRTGADQQP", "length": 154 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "M0QWR4-1", "protein_name": "Aly/REF export factor family member 14", "gene_name": "Alyreffm17", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADKMDMSLEDIIKLTKIQQRRHDRPDSRVNRGTGSKRYRPAFTHGGRNRLAPYCRPKQLPDKWQHDLFIGGFRGQNHVDTGGKLFLSNLHFGVSDADIQLLFAEFGTLKKSAVHYDRCGRSLGTAQVHFERKADALKAMREYNGAPLDGRPMNIQLATSQIDRQGRPAQSKNRGGMTRNPGSGVLSGGGTKKWTLGGSQGRGRGTIRNSKLQQQQQQQKQKQQQQQQKQQQKQQQKQQQQLSAEELDAQLDAYQEMMDTS", "length": 261 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "M0R3T3-1", "protein_name": "Peptidase S1 domain-containing protein", "gene_name": "ENSRNOG00000067174", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRFLVLCLILSLGDYGAFPLIQSRIHRGCKGERHSQPWQVAMYHYDKAVGWGWHPSPTTMSTSPSHNKVRLGQHSLDADGDTGQDVPVRHSIPHPLYNRSLQMPTFLSPDADNSHNLMLRQLREPANTTEAVRVTEEPTEEAKLGSRCLASGWGSTRPDKCMPGMLQCVDLTLMSSDVCTYAYSQRVTESMLCAGHQEGSRDTCMGDSGTTLICDRMLQGITSWGGNPCA", "length": 230 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0R777-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "Smokwl5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASKSKEKTLGSHYKILSYLGQGSFGTVNLAWHLKTQALVAIKMLEISKETISSILSERAILETLHHPNIIRLFQVLITSSHVNFVLEYAPGGSLFELIKEGGPLQEEVAKKIFGQTVSAVKYCHNLDIVHRDIKPQNILTDAEGNGKLTDFGLATKFRPGTLLKELCGTKEFYAPELVLREPYNGKKTDVWSLGVLLYFISTGYCPFRGVTTKDMEKKIATGTYTIPTYFSGQLENLIHQILTVSPEMRPSIEDIEKHPWVRKCEVNIPTITCPDYKIVEMLCGMGYNANKILESLQKKKYDEPMAAYLILKDKVRQEIEHGTTTSDMPVDQGPLPPQSPAHHSVSGLPLKRRASEPNFGLLHIWPPGEQVARHNVARSVSMPPIALYGTKKQNSTSTSALHSRPVASPCVCNTILEIEIPLPTKQDFDMKTSSPPQRIGYFQRLCQRIRDCLSRLCCFLWAPKVHSPRKWLP", "length": 474 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0R9M1-1", "protein_name": "Olfactory receptor family 52 subfamily N member 1B", "gene_name": "Or52n1b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSLLNVSSLTPASLILNGIPGLEEVNLCIFFPLFTMYSIALTGNFGLIYLIYSEEVLHRPMYIFLALLSFTDVLMCTSTIPNTLFISWFNFKKIDFKACLAQMFFVHTFTGMESGVLVLMVLDLYIAMCYPLRYATILTNVVIAKAGMLTFLRGVALVIPFIFLTKRFPYCKGNVIPHTYCDHISVAKISCGNVQINAIYGLMVVLLIGDFDIPCITVSYTMILWAAVSLSSADARQKAFSTCTAHICAIVITYVPAFFTFFTHRFGWHTIPSHIHIIMANLYLLMPPTMNPIVYGVKTKQIQKRVIRFFFKGRENSSHKF", "length": 321 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0R9X6-1", "protein_name": "Paired immunoglobin-like type 2 receptor beta 1 like 2", "gene_name": "Pilrb2l4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALLVSLPEQNLAMAWILLLLLLAACLHTGNSAGYQKTQDYGVNQPEQLTGIQGGSIEIPFSFYFPWELAKDPQMSIAWRWKVFFGEVIYNSTLLFLHEHFKGRLIMNWTQGQTSGVLRILNLKANDQSTYFSRIFLQATEGMKLWQSRAGTKLIIHALSTTMASPSIIPSAVPTAGLENTRGQRNPSLLNLGAMVGMVMAKVVVIIPLYGWVIFLWWKQRLPTARISHQVSLHHTPCIPQSSMSSLWESELVAAGFSCESHSWITPTSAMGARIPSPWNQGPPVCLWA", "length": 289 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RAD6-1", "protein_name": "Olfactory receptor", "gene_name": "Or1f19f", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRSTNQSSVSEFLLLGLSRQPQQQQLLFLLFLIMYLATVLGNLLIILVISTDSHLHTPMYFFLSNLSFVDVCFSSTTVPKVLANHILSSQAISFSGCLTQLYFLCVSVNMDNFLLAVMAYDRFVAICHPLYYTTKMTHQLCVLMVSGSWVTASLNALLHTLLMARLSFCGDNIIHHFFCDVTPLLKLSCTATNLNELMILTEGAVIMVTPFVCILISYIYITNAVLRVSSFRGGWKAFSTCGSHLAVVCLFYGTIIAVYFNPVSSHSSEKDTAATVLYTVVTPMLNPFIYSLRNNDLKGALRKVVHRKI", "length": 309 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RBH5-1", "protein_name": "Surfactant associated 2", "gene_name": "Sfta2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEPSMCLFLLLTLLCSSLAGPTKVTLQVKLTEASQAKTSQDSGFLDMLQKICLLLHLSPGTNVTLHHKGPPHHLTCRA", "length": 78 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RCJ6-1", "protein_name": "EF-hand domain-containing protein", "gene_name": "AABR07013776.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MADQLTEEQIAEFKEAFPLFDRDGDQTVTTKELGMVMGSLGQNPTEAELQDMISEVDADGNGTINFPEFLTMMARKMKGTDVEEEIREAFRVFDKDGYTSAAEFRHVMTTLGEKLTDEEVDGMIREADMDGDGQVIYEEFVQMVTAK", "length": 147 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RCP1-1", "protein_name": "Leukocyte immunoglobulin like receptor B3", "gene_name": "Lilrb3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVSTLTALAYLGLILGSENPVLSGAFTKPTIKMVPSNVVTTGKQVTIFCEGSSHAKEYRLHKEGSPDYLTPTTFLETENKAKFSISPIQWNNAGQYWCSYRSLTNKLRQSDIMELVVTGVILGEVTLSALPSYVVTSGRNVTLQCASQVVYDRFILMKEDEKFSTAMPSWKIYPVLWGAIFTLGPVTSNQRWRFTCYGYYLSSSLIWSKPSNHLELLVSGTLHKPILWAHPGSMVTSGSPVTIWCEGDQETQTYVLYRQGSLESWNRQTQKDYNNKAEFTIPSVTYLNAGHYFCYSYTSAGWSEHSDTLELVVTGVYKKPIFLALKNPIVNLGVTVTISCTSNQSFNCFLLMDDDQKIYRFFDLQYSYSGESLARFQVGPITSRQRWRFRCYGYYTDNPQVWSEASDPLDFLVSGNLQKPTLWAEPGSVIESGNSVTIWCEGTMETQIYFLYKEGSPSSWLRQTPKEPGNKAMFFIAFMEKHNAGQYRCYCYNFGGWSQHSDTLELVMTGVHHGKPTLSAFPSPMVTSGGNVTLYCASSTIYDWYIVTGQDLKFSRFQRAQFIPTEMSQALFSEISVASRKKGPFRCYGFNESTPHLWSEASNPLEIHVSGVSRKPSLLNQQGPVLAPGENLTLRCSSELSYDRFSLSKEGRSDLPQLSVSQSQTGEYYANFFLYSVDFSIAGQYRCYGASRFSSEWSAPSVPQDILVTGHPPITPSLSVNPGTIVSSGENVTLLCQSSIPMDTFFLFKKGDAYPYMHQRLKFQGPQCKAEFSLSAVTPNIGGIFTCFGSQSSSPYLLSHPSVPVEIKVSGLAKYQKSLIWVSVVFFLLFFVLTLFFFLRLWHQNKHRKGVQTKIDLQHPEGAVEPKSIVGHLQKSSRPAPAIQEEILCEKRWPGREITEVSASDATVKVTRSADNVELGILSQHQDDPSIHLYAQVKPARLRRAQTTSSSLFPKELQHSKHRQKNRDQVIDQQADTSQDSHAVIYAQLHIMTPRQGRQTSLFPGRIC", "length": 1008 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RCQ2-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "LOC100361204", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDSSIPDPEADLIQLNGSYHTETSPCVIESRVMILLSIIIAFFGLAGNAMVLWLLAFRMRRNVFSVYILNLAGANFLFLCTHTAFSLEKIIVLFHSVHIHIPLLFYTLSTLAYLAGVSMVTAISAEYWLSGIWPYWYQGQRLKHTTTVICTGLWGLALLLSLLEGKSCGFLGSTYNQDVCWKLDFIIVAWLLVLFAVLSRSIQVLLVRIFCGSQRTPVTKLHVTIVLTALVLVICGFPFGIIFYLLYWTTEVYYIMPCNSFHETILLLSYINSCANPIICLLVGSIRHCRFQCGTLRLLLHRAMQDIPEEEGEELEEVVGERVQSSIP", "length": 328 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RCW7-1", "protein_name": "Uncharacterized protein", "gene_name": "Pilrb1l3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALLVSLPEQNLAMAQLLLLLLSAACLHTGNSAGYPKKNVFSVDQPAVLSGVQGGSIEISFSFYFPWELAKVPQMSIAWRWKNYHGEYIYNSTQPFIHEHFKGRLIVNWSQGQTSGVLRILNLKENDKATYFSRVFLPTTEGMKSWQSVAGTQLIIIHAPSTTVVSPSIIPSVVPIAGLEDTRGKRTPSLLNLGAMVRMVVSKVVVIIALYGWVIFLWWKQRSAWSLLSFLTTWKSEEQMQMNTAPAPKEFK", "length": 252 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RCY4-1", "protein_name": "Retinoic acid early-inducible protein 1 domain-containing protein", "gene_name": "AABR07000137.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSAPLGSLGRKSKNQSLGLDMLGTVLSTDSLSCTFTVKYRSSPGQCSVNGKPLLLFNDERQNSPVGKPEKKGNATKVCAELNQSLKDIFQKMMNLESWLFESKGNHTLQVTVQSQYNQGIFMDGCWVFTIDRQYPFYFYPKIMTWRESHPDASRTVSQWQNNRQVAQSLRTCSMGDFSQCLRKLLTDSREVPRSTITTLDPTQPSSAIQIPPTVDSASSVFTTWSQYIFVLILCLAILIINALIP", "length": 246 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RD07-1", "protein_name": "Uncharacterized protein", "gene_name": "ENSRNOG00000064269", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRMMAMQMMTNSISDAMERYKELIQVNSSYNIRQSQLLREQAQLKNNIQILLNEKRELLVEETELPASSVEAKRLCEEAGMNICDPRAKQQQV", "length": 93 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RDP5-1", "protein_name": "Zinc finger protein 353", "gene_name": "Zfp353", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDVAETPGASQTVPCNTQPSPVESSQLVSGQSSEMPTWKKTVMASACCNPQETACTQNSTAHPGKASDFYFGEPSETASFIQQVVSAEQKSSPAGSCLMNLSSTTKSCLSHPLKTEVLDTRKTLCNEGHWGRTLNSDKTLLIQITTMYESQWRTLGNHPVAPSGYHEGQAPNMDHLVDSVSNQTFIGDLEMEPSCNHVLYTDQFITSFSEQNPFGDQQRSPVADNRFYADQKILPNGYQTFYEPQMSTNYQITCVCGQNVCRCQEILLSGEHLLSEYQTSGYRYDQDLIVNLQVTSPIGGEPLHDSQIPNSNFDTTSCGTKRTTSSEEDNLAWHPETSLSSEETFLDQMRTSVDQNVYPSHNGTLKIEESLEPQVTSLSNQAPYVGESSDTSNSPLIQIQPQEISSASGLDQGQHPEIKLDLKTQSPVSLKNPHNSKRYCCTYQGCKKSYKKSQHLKDHMKKHTGVKPYMCNKPGCDWKFFRLVDLNRHKQKHSGERPYPCPMCNKNYSRFYYLKQHLRSHIQASPTTAT", "length": 530 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M9MSI7-1", "protein_name": "Uncharacterized protein", "gene_name": "Dmel\\CG42818", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MFIHQREQLPFKHNEQDPNYLAPVIQKRKPMDKDPRNPLKRLKFLQEFPTQSSKGDLDDLKYPTQLEGRHDSPKYDKTFHTEIHANNETDSQELENIILEKNLQDSKTEFQENRASQPKNMHSFQIPEAIESHFNNKELQNENDLHKGLKQQYRSGSEQDKSGPENVREIASKLILQWAENQRSLLDSFVKAITDVLKVHDSKLNMKINISPRDIMILKDMLKQLLESIMQLREGSTSTRARIVLNKWIETQKSLIDSFSQAIQNTNQNVDNIANVYEVMENLNKNLRELVILLSDKESFPTTESSSSQQTTSIYATTTFYLTSSTFGSTHPIVDENINRVNIMGNLIKGLRNIMVQMDETNKTSSSTSYTTTESTYIQPSTSTYLNAEVTTSHPTTSTYEVTNIITDESKIKDMFNLIKGIEDLISQYNGKHKFTSTTSLTGKSNSREPTMTTYSSAGGITSHSFTTTSPKTVTTSSSHSTTESSPSHPTTSNYEVTVFDQDSHKFKVMKNLIKELKGLIEHFSDTKNITSTTYSTGDSKSFQPTATTPDSTDRSSSQPITFPESTTSTTNLQSTITNHLSTESTSSQLNTTLSITGTTTPNLTTSTHDFKDQINDDDSKSLKHLIKILSDLVYSLNDKNNIKSTSQLTTESTFNSSINITNSTTVASSTFSTTESMAIHSTPYLSTREITVFQFNDVENINPIISNNSTTVTTNIHSSTYTTSTTDNTTSYPNLSTTESSPTFDSTISHSNTSSQTRSLGSYKDKIKNIVELLKKLRKIQKTLADKSKGQLSPMLISRIKAVLKQIVAGNIDSVNGDSTELEILLSTTVNPNEDTTDLTMEKLLKLFDDFERMYNVLLDDSIQSTTQSTTQNNTIFSTTYSTIFSTTQSISTTSPTQYALTSSTPNTSTTSHSSTPSSINNLRSDESNNHQPIVDAIQQLKMALYHDFYAFKKSQEERMEKILQLLNGKPIDRRTKTIAKPRTIRKKVSREIQKRNSDVKEDKIHHYKADKFIKNPKNGNQDSHIPKPILNSARSKIKDVPLKLSAIKVNGGLKHLPSKRKANEEVSAMHEIFPEPVSILPHK", "length": 1085 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "O08640-1", "protein_name": "Keratin-associated protein 14", "gene_name": "Krtap14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSCNSCSGTFSQSFGGQLQYPISSCGSSYPNNVFYSTDLQTPITHQLGSSLHSGCQETFCEPTNCQTAYVVSRPCQRPFYSQRIRGPCRPCQSTFSGSLGFGSRGFQSFGCGYPSQGFGSHGFQSVGCGTPTFSSLNCGSSFYRPTCFSTKSCQSVSYQPTCGTGFF", "length": 167 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "O21032-1", "protein_name": "Large ribosomal subunit protein uL16m", "gene_name": "mrpl16", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKIPNRQKFTKNHKRNLITKETRKTGLVLGNYGIKATETGYLKMKQMERIKGDLVKKLKDNMDIYFNFYPLFGLTNKGTARMGAGKGEVSEWYVLVKKGSIVVEFIKSRMTAGAMQKVIRYSANKWPIKVRMTQIKQGLYEKKI", "length": 144 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "O21042-1", "protein_name": "Cytochrome c oxidase subunit 1+2", "gene_name": "2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKILEIYDKQIAEKEGNIFIFISKWIISVDHKNIGTMYTNFSILAGIVGTLLSLVIRMELSTGNMLDGDGQQYNVIVTAHGLIMIFFVVMPAMLGGFANWFIPIMVGSPDVAFPRLNNISLWLIIVSFFLLLTSSCVGIGVGTGWTVYPPLSTMEYHPGHAVDVGILSLHIAGASSLLGAINFLTTVFNMKIAGLSWSKVSLFVWSILITAVLLVLSLPVLAGGLTMLITDRNFETTFFDPIGGGDPILYQHLFWFFGHPEVYILILPGFGLVSIILSKYSNKGIFGVKGMISAMSAIGFLGFLVWAHHMYTVGLDVDTRAYFTAATMIIAIPTGIKIFSWLATLWGGVIKITTPMLFVIGFLVLFTIGGLTGVVLANGGLDISLHDTYYVVAHFHYVLSMGAIFAIFAGYYYYYSIMNSTRLFGVVRYNEQLGRIHFWTMFIGVNVTFFPMHFLGLAGMPRRIGDYPDAYIGWNLIASYGSLITAFGLLFFVVNIFTPYIRRSVNIKNGAIILMGLDFARDWQIGFQDPATPIMEGIIDLHNYIFFYLIVVAVFIGWVMGRILWRFSYKWSYPTIGDIEIFKNFTAYNQIIHGTVIEIVWTLIPTVILYLIAIPSFTLLYAMDEIINPTVTIKIIGHQWYWSYEYGDNASNLIEFDSYMVYERDLAEGQLRLLEVDNAMVVPVKTHIRLIITSGDVLHSWAIPSFGIKVDAVPGRLNQIGLYVKREGTFYGQCSELCGVDHGFMPIKVQAVKLGEYFSKLNEK", "length": 764 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "O21049-1", "protein_name": "Cytochrome c oxidase subunit 3", "gene_name": "cox3", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKGFFENLFRQNVRSVINTGKKVGARAAAREIINQEWGYPLANHEVLFLTNVYQPKHMKRHPFHIVRGTVAPLAVTLPLGFFVLNYFGVISSKLGLLIALSSFIGGLVIWTISIIFDSLYDQQHTYEVKRGLVMGMMMFIISEVMFFFSFFWSYFYISLSPNIAIGCVWPPYGLTVYSYMGLPLLNTVLLLLSGAILTDGYTILTEQKAVHEKNEKVLAVEEAFKNLMNLYKTKNSINTLTFVDERRDKFFGKESRQEDKIAEQKLIAISAGVKELRDLDWDLYFFENPENIEPNYKEPTNLSVIEYALITIYLKKRNKVIKTRLYFTLLCAVVFLACQGYEYFFAPFSMNDGIYGSLFFLLTGFHGFHVLVGSILIGIITIRFIVGNFNLLNVGTNFQIYKNKSTGFACTLFYWHFVDIVWIFLYIVIYWWGSR", "length": 435 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "O23373-1", "protein_name": "Formin-like protein 3", "gene_name": "FH3", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MGRLRLAFLAISLVVFVCVSEEIFSRGGLNLLRFSVYGEDVAEQTWIHQNPRRKLISYPKKFSVSAPNLAFGPAPSFAPGPGPSFAPGPAPNPRSYDWLAPASSPNEPPAETPDESSPSPSEETPSVVAPSQSVPGPPRPPPQREKKDDILMKLIIAVASTAVLTFVFVALMFLCCFKRNCNNAVGSRDGPRDEGPLLRLSTGSTENSPTVASTSRKMFSVASSKKRSFLSRVSLKRNGHEFSTAESSSAAGLPPLKLPPGRSAPPPPPAAAPPPQPPPPPPPKPQPPPPPKIARPPPAPPKGAAPKRQGNTSSGDASDVDSETGAPKTKLKPFFWDKMANPDQKMVWHEISAGSFQFNEEAMESLFGYNDGNKNKNGQKSTDSSLRESPLQYIQIIDTRKAQNLSILLRALNVTTEEVVDAIKEGNELPVELLQTLLKMAPTSEEELKLRLYSGDLHLLGPAERFLKILVDIPFAFKRIESLLFMISLQEEVSGLKEALGTLEVACKKLRNSRLFLKLLEAVLKTGNRMNVGTFRGDAQAFKLDTLLKLSDVKGTDGKTTLLHFVVLEIIRSEGVRALRLQSRSFSSVKTDDSNADSSPQSVERYRSTGLQVVTGLTTELEDVKRAAIIDADGLAATLANISGSLTNAREFLKTMDEESDFERALAGFIERADADFKWLKEEEERIMVLVKSSADYFHGKSAKNEGLRLFAIVRDFLIMLEKVCREVKETTKTTNHSGKKESEMTTSDSNQPSPDFRQRLFPAIAERRMDSSDDSDDEEDSSPS", "length": 785 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "O35698-1", "protein_name": "RNA-binding motif protein, Y chromosome", "gene_name": "Rbmy", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAETNQPGKIFIGGLNIKTRQKTLQEIFGRFGPVARVILMRDRETKKSRGFAFLTFRRLADAKNAVKEMNGVILDGKRIKVKQARRPSSLESGSKKRPPSFSRTRGASRILKCGRGGRSRARSGPSCEGNLGGDRYTPNFNVSSSGRHFAVKRNPSSKRDDPPSKRSATSAQTRSNTGLRGREPHRREISRNMPRGEPASSRRDEYPLPRDYGQSSNDRKYESTSRGYCDYGNYHSREESASKVFSDHAGYLGGRDRDFSEYLSGNSYRDTYRSYGRFHEAPSARGGNNRYDDYSNSQDGYGGRGEPYISNRSNIYSSDYERSGRQEVLPPPIDREYFDREGRQERGHSPKDGLYSASRESYSSNTKIWGIPWRSWRKQI", "length": 380 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "O60309-1", "protein_name": "Leucine-rich repeat-containing protein 37A3", "gene_name": "LRRC37A3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTSAQCPALACVMSPLRFWGPWPLLMWQLLWLLVKEAQPLEWVKDPLQLTSNPLGPPEPWSSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGELPLEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGIIHQLSTPQSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQQQPVQPSESSREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESMTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEETSTQLPDLGLAIIPEPTTETGHSTALEKTTAPRPDRVQTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEMLSCIDLNPEQRLRQVPVPEPNTHNGTFTILNFQGNYISYIDGNVWKAYSWTEKLILRENNLTELHKDSFEGLLSLQYLDLSCNKIQSIERHTFEPLPFLKFINLSCNVITELSFGTFQAWHGMQFLHKLILNHNPLTTVEDPYLFKLPALKYLDMGTTLVPLTTLKNILMMTVELEKLIVPSHMACCLCQFKNSIEAVCKTVKLHCNSACLTNTTHCPEEASVGNPEGAFMKVLQARKNYTSTELIIEPEEPSDSSGINLSGFGSEQLDTNDESDVTSTLSYILPYFSAVNLDVKSLLLPFIKLPTTGNSLAKIQTVGKNRQRLNRVLMGPRSIQKRHFKEVGRQSIRREQGAQASVENTAEEKRLGSPAPRELKQPHTQQGPEKLAGNAVYTKPSFTQEHKAAVSVLKPFSKGAPSTSSPAKALPQVRDRWKDLTHAISILESAKARVTNMKTSKPIVHSRKKYRFHKTRSRMTHRTPKVKKSPKVRKKSYLSRLMLSNRLPFSAAKSLINSPSQGAFSSLRDLSPQENPFLEVSAPSEHFIENNNTKDTTARNAFEENVFMENTNMPEGTISENTNYNHPPEADSAGTAFNLGPTVKQTETKWEYNNVGTDLSPEPKSFNYPLLSSPGDQFEIQLTQQLQSVIPNNNVRRLIAHVIRTLKMDCSGAHVQVTCAKLVSRTGHLMKLLSGQQEVKASKIEWDTDQWKTENYINESTEAQSEQKEKSLEFTKELPGYGYTKKLILALIVTGILTILIILLCLIEICCHRRSLQEDEEGFSRDSEAPTEEESEALP", "length": 1634 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "O80489-1", "protein_name": "small monomeric GTPase", "gene_name": "SARA1A", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MFLFDWFYGILASLGLCKKEAKILFLGLDNAGKTTLLHMLKDERLVQHQPTQHPTSEELSIGKINFKAFDLGGHQIARRVWKDCYAKVDAVVYLVDAYDRDRFVESKRELDALLSDEALANVPCLILGNKIDIPYASSEDELRYYLGLTNFTTGKGIVNLEDSGVRPLEVFMCSIVRKMGYGEGFKWLSQYIK", "length": 193 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "O80614-1", "protein_name": "RING-type E3 ubiquitin transferase", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSSDMRDERFFYHRYLSVTNRTTPTTATNLPTSTSNMRSTSLMTPRVAHTSMSSGGDFPDDRFFHARHQSATDRAASNRSRAIMPISTTNVPSSTSNSPRVLQTSMSRRGTSPMSSSTRRSVQASMSARETVPSSTSTRSMQTSTSTPEIMPTSSRNVITSSEEVANTFTQTSYIQFGSLWETNTTPSTRSWPTVPSSNSPRVLQTSMSRRGTSPMSSSTRRNVQSSMSGRETVSSSTSTSSMQTSMSTPEIMPTSSRNVITRSEEVANTFSTQTPYIQFGRLWETNTTSSTRSRTTVPTSTTNVPSSNSSRVLQTSMSTRGTFPMSSSTRMSVQASMLAPGTVSSSMSTVEIMPTSARNMITMSEEVANSFTQTSYIQFGSLWETFKTVTKLSRVAMVENGECVICLEEWRKETYVTSSTSNMRTSSLMTLTRFIDEQISLRATVSSTRTTARLLTNESPATIRAVAMLPRVAMVEKGECVICFEEWSKSDMETELPCKHKYHLECVEKWLKIHTSCPQCRYKLSCVYKSFLML", "length": 535 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "O81153-1", "protein_name": "Proteasome subunit beta type-3-B", "gene_name": "PBC2", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSIFEYNGSAVVAMVGKNCFAIASDRRLGVQLQTIATDFQRISKIHDHLFIGLSGLATDVQTLYQRLVFRHKLYQLREERDMKPETFASLVSAILYEKRFGPFLCQPVIAGLGDDNKPFICTMDSIGAKELAKDFVVSGTASESLYGACEAMFKPDMEAEELFETISQALLSSVDRDCLSGWGGHVYVVTPKEVKERILKGRMD", "length": 204 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P00757-1", "protein_name": "Kallikrein 1-related peptidase-like b4", "gene_name": "Klk1b4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWFLILFLALSLGGIDAAPPVQSQVDCENSQPWHVAVYRFNKYQCGGVLLDRNWVLTAAHCYNDKYQVWLGKNNFLEDEPSDQHRLVSKAIPHPDFNMSLLNEHTPQPEDDYSNDLMLLRLSKPADITDVVKPITLPTEEPKLGSTCLASGWGSTTPIKFKYPDDLQCVNLKLLPNEDCDKAHEMKVTDAMLCAGEMDGGSYTCEHDSGGPLICDGILQGITSWGPEPCGEPTEPSVYTKLIKFSSWIRETMANNP", "length": 256 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P01241-1", "protein_name": "Somatotropin", "gene_name": "GH1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATGSRTSLLLAFGLLCLPWLQEGSAFPTIPLSRLFDNAMLRAHRLHQLAFDTYQEFEEAYIPKEQKYSFLQNPQTSLCFSESIPTPSNREETQQKSNLELLRISLLLIQSWLEPVQFLRSVFANSLVYGASDSNVYDLLKDLEEGIQTLMGRLEDGSPRTGQIFKQTYSKFDTNSHNDDALLKNYGLLYCFRKDMDKVETFLRIVQCRSVEGSCGF", "length": 217 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P02762-1", "protein_name": "Major urinary protein 6", "gene_name": "Mup6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMLLLLCLGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILASDKREKIEDNGNFRLFLEQIHVLENSLVLKFHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAQLCEEHGILRENIIDLSNANRCLQARE", "length": 180 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P04071-1", "protein_name": "Kallikrein 1-related peptidase b16", "gene_name": "Klk1b16", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWFLILFLALSLGGIDAAPPVQSRIVGGFKCEKNSQPWQVAVYYHKEHICGGVLLDRNWVLTAAHCYVDECEVWLGKNQLFQEEPSAQNRLVSKSFPHPGFNMTLLTFEKLPPGADFSNDLMLLRLSKPADITDVVKPIDLPTKEPKLDSTCLVSGWGSITPTKWQKPDDLQCMFTKLLPNENCAKAYLLKVTDVMLCTIEMGEDKGPCVGDSGGPLICDGVLQGTVSIGPDPCGIPGVSAIYTNLVKFNSWIKDTMMKNA", "length": 261 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P04644-1", "protein_name": "Small ribosomal subunit protein eS17", "gene_name": "Rps17", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGRVRTKTVKKAARVIIEKYYTRLGNDFHTNKRVCEEIAIIPSKNLRNKIAGYVTHLMKRIQRGPVRGISIKLQEEERERRDNYVPEVSALDQEIIEVDPDTKEMLKLLDFGSLSNLQVTQPTVGMNFKTPRGAV", "length": 135 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P05817-1", "protein_name": "Prestalk D11 protein", "gene_name": "ampA", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MLNKLILLLILSSCLVLSVKSEVNVDCSLVRCAQPICKPHYRLNMTDSCCGRCEPCTDVACTLQVKYCQDGEVPTGCCPCTLPPTKPDCSLVKCARPVCKPYYRLNMTDSCCGRCEPCTGVACTLQIKYCKDGEVPTGCCPCTPQPTKKPDCSKVPCPKILKYCQEGELPTGCCPCTPQPTKKPDCSRVPCPKILKYCKEGELPTGCCPCTPQPTKKPDCSDVMCTMDIRYCKNGELPTGCCPCTPQETKVPDCSKAMCTMDIKYCKPGEKPFGCCPCRENLTQ", "length": 284 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "P06325-1", "protein_name": "T-cell receptor gamma chain V region 5/10-13", "gene_name": "Tcrg-V1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLLLRWPTFCCLWVFGLGQLEQTELSVTRATDESAQISCIVSLPYFSNTAIHWYRQKAKKFEYLIYVSTNYNQRPLGGKNKKIEASKDFQTSTSTLKINYLKKEDEATYYCAVCRSGTSWVKIFAKGTKLVVIPP", "length": 135 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P06349-1", "protein_name": "Histone H1t", "gene_name": "H1-6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSETAPAASSTLVPAPVEKPATKRRGKKPGMATARKPRGFSVSKLIPEALSMSQERAGMSLAALKKALAAAGYDVEKNNSRIKLALKRLVNKGVLVQTKGTGASGSFKLSKKAASGNDKGKGKKSASAKAKKLGLSRASRSPKSSKTKVVKKPKATPTKGSGSRRKTKGAKGLQQRKSPAKARATNSNSGKSKMVMQKTDLRKAAGRK", "length": 208 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P07628-1", "protein_name": "Kallikrein 1-related peptidase b8", "gene_name": "Klk1b8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRFLILFLALSLGGIDAAPPLQSRVVGGFNCEKNSQPWQVAVYDNKEHICGGVLLERNWVLTAAHCYVDQYEVWLGKNKLFQEEPSAQHRLVSKSFPHPGFNMSLLTLKEIPPGADFSNDLMLLRLSKPADITDAVKPITLPTKESKLGSTCLASGWGSITPTKWQKPDDLQCVFLKLLPIKNCIENHNVKVTDVMLCAGEMSGGKNICKGDSGGPLICDSVLQGITSTGPIPCGKPGVPAMYTNLIKFNSWIKDTMTKNS", "length": 261 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P07647-1", "protein_name": "Submandibular glandular kallikrein-9", "gene_name": "Klk9", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MWFLILFLALSLGQIDAAPPGQSRVVGGYNCETNSQPWQVAVIGTTFCGGVLIDPSWVITAAHCYSKNYRVLLGRNNLVKDEPFAQRRLVSQSFQHPDYIPVFMRNHTRQRAYDHNNDLMLLHLSKPADITGGVKVIDLPTEEPKVGSICLASGWGMTNPSEMKLSHDLQCVNIHLLSNEKCIETYKNIETDVTLCAGEMDGGKDTCTGDSGGPLICDGVLQGLTSGGATPCAKPKTPAIYAKLIKFTSWIKKVMKENP", "length": 259 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P08932-1", "protein_name": "T-kininogen 2", "gene_name": "", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKLITILLLCSRLLPSLAQEEGAQEMDCNDETVFQAVDTALKKYNAELESGNQFLLYRVTEGTKKDGAETLYSFKYQIKEGNCSVQSGLTWQDCDFKDAEEAATGECTTTLGKKENKFSVATQICNITPGKGPKKTEEDLCVGCFQPIPMDSSDLKPVLKHAVEHFNNNTKHTHLFALTEVKSAHSQVVAGMNYKIIYSIVQTNCSKEDFPFLREDCVPLPYGDHGECRGHTYVDIHNTIAGFSQSCDLYPGDDLFSLLPKKCFGCPKNIPVDSPELKEALGHSIAQLNAQHNHLFYFKIDTVKKATSQVVAGTKYVIEFIARETNCSKQTNTELTADCETKHLGQSLNCNANVYMRPWENKVVPTVRCQALDMMISRPPGFSPFRLVQVQETKEGTTRLLNSCEYKGRLSKAGAGPAPDHQAEASTVTP", "length": 430 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P0C0S7-1", "protein_name": "Histone H2A.Z", "gene_name": "H2az1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGGKAGKDSGKAKTKAVSRSQRAGLQFPVGRIHRHLKSRTTSHGRVGATAAVYSAAILEYLTAEVLELAGNASKDLKVKRITPRHLQLAIRGDEELDSLIKATIAGGGVIPHIHKSLIGKKGQQKTV", "length": 128 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P0C2B7-1", "protein_name": "Large ribosomal subunit protein mL52", "gene_name": "MRPL52", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAALGMLLSTGVRRLHCGSAARAGSQWRLRQGLAANPSGYGPLTELPDWSYADGRPAPPMKGQLRRKAQREKFARRVVLLSQEMDAGLQAWQLRQQEKLQEEKRKQQNALKPKGVLLQNPGPSQ", "length": 124 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P0C644-1", "protein_name": "Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1", "gene_name": "Ppip5k1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MWSLTANEDEDESATAHFFLGAGDEGLGTCGIGMRTGESDSELLEDEEDEVPPEPQIIVGICAMTKKSKSKPMTQILERLCRFDYLTVVILGEDVILNEPVENWPPCHCLISFHSKGFPLDKAVAYSKLRNPFLINDLTMQYYIQDRREVYRILQEEGIDLPRYAVLNRDPACPEECNLIEGEDQVEVNGAVFPKPFVEKPVSAEDHNVYIYYPSSAGGGSQRLFRKIGSRSSVYSPESSVRKTGSYIYEEFMPTDGTDVKVYTVGPDYAHAEARKSPALDGKVERDSEGKEVRYPVMLTAMEKLVARKVCVAFKQTVCGFDLLRANGHSFVCDVNGFSFVKNSMKYYDDCAKILGNTIMRELAPQFQIPWSIPTEAEDIPIVPTTSGTMMELRCVIAIIRHGDRTPKQKMKMEVTHPRFFALFEKHGGYKTGKLKLKRPEQLQEVLDITRLLLAELEKEPGAEIEEKTGKLEQLKSVLEMYGHFSGINRKVQLTYYPHGVKASSEGQDLQREPPAPSLLLVLKWGGELTPDGRVQAEELGRAFRCMYPGGQGDYAGFPGCGLLRLHSTFRHDLKIYASDEGRVQMTAAAFAKGLLALEGELTPILVQMVKSANMNGLLDSDSDSLSSCQHRVKARLHHILQQDAPFGPEDYDQLAPTGSTSLLNSMSVIQNPVKVCDQVFALIENLTHQIRERMQDPSSVDLQLYHSETLELMLQRWSKLERDFRQKSGRYDISKIPDIYDCVKYDVQHNGSLGLQGTAELLRLSKALADVVIPQEYGISREEKVEIAVGFCLPLLRKILLDLQRTHEDESVNKLHPLYSRGVLSPGRHVRTRLYFTSESHVHSLLSVFRYGGLLDETKDAQWQRALAYLSAISELNYMTQIVIMLYEDNTRDPLSEERFHVELHFSPGVKGVEEGSAPAGCGFRPASSENEEMKTDPGSIENLCPAKPSDEPDRALQTSPQPVEGTGLPRRSPLIRNRKAGSMEVLSETSSSRPGGYRLFSSSRPPTEMKQSGLGSQCTGLFSTTVLGGSSSAPNLQDYARTHGKKLPPAGLKHRDELLFVPAVKRFSVSFAKHPTNGFEGCSMVPTIYPLETLHNALSLRQVSEFLTKVCQRHTDAHAQASAALFDSMHNHQASDNPFSPPRTLHSPPLQLRHRSEKPPWYSSGPSSTVSSAGPSSPTTVDGNSHFGFSDQSSVNTQMIEEKQGLGLLQETPGDGTPEFHIELAESTQSPQEPPVEISPPGSQDDTEVNQTCQEVPDTIQPCHDILEEIGQPNQEVPDISQLLLKNHDTATNTCQPCQASQLSKKVYEEICQLCQDNPEESNQLCQEVSVELGRMVHRFPVSIGSTTQETLMEIGRPTQEIPEEPCQEFSEKVGMLTQKASAISELSQDILETDNPSQELSEETDLQAQEVSEEIDQEPEVVDELSNEDIS", "length": 1434 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P0C7H9-1", "protein_name": "Inactive ubiquitin carboxyl-terminal hydrolase 17-like protein 7", "gene_name": "USP17L7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEDDSLYLGGDWQFNHFSKLTSSRLDAAFAEIQRTSLSEKSPLSSETRFDLCDDLAPVARQLAPREKLPLSSRRPAAVGAGLQKIGNTFYVNVSLQCLTYTLPLSNYMLSREDSQTCHLHKCCMFCTMQAHITWALHSPGHVIQPSQVLAAGFHRGEQEDAHEFLMFTVDAMKKACLPGHKQLDHHSKDTTLIHQIFGAYWRSQIKYLHCHGVSDTFDPYLDIALDIQAAQSVKQALEQLVKPKELNGENAYHCGLCLQKAPASKTLTLPTSAKVLILVLKRFSDVTGNKLAKNVQYPKCRDMQPYMSQQNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQEGQWYKMDDAEVTASGITSVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRPATQGELKRDHPCLQVPELDEHLVERATQESTLDHWKFPQEQNKTKPEFNVRKVEGTLPPNVLVIHQSKYKCGMKNHHPEQQSSLLNLSSTKPTDQESMNTGTLASLQGSTRRSKGNNKHSKRSLLVCQ", "length": 530 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0CW02-1", "protein_name": "Lymphocyte antigen 6C1", "gene_name": "Ly6c1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDTSHTTKSCVLILLVALLCAERAQGLQCYECYGVPIETSCPAVTCRASDGFCIAQNIELIEDSQRRKLKTRQCLSFCPAGVPIRDPNIRERTSCCSEDLCNAAVPTAGSTWTMAGVLLFSLSSVVLQTLL", "length": 131 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P0DKL4-1", "protein_name": "Spliceosome-associated protein 130 A", "gene_name": "SAP130A", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MYLYSLTLQQATGIVCAINGNFSGGKTQEIAVARGKILDLLRPDENGKIQTIHSVEVFGAIRSLAQFRLTGAQKDYIVVGSDSGRIVILEYNKEKNVFDKVHQETFGKSGCRRIVPGQYVAVDPKGRAVMIGACEKQKLVYVLNRDTTARLTISSPLEAHKSHTICYSLCGVDCGFDNPIFAAIELDYSEADQDPTGQAASEAQKHLTFYELDLGLNHVSRKWSNPVDNGANMLVTVPGGADGPSGVLVCAENFVIYMNQGHPDVRAVIPRRTDLPAERGVLVVSAAVHKQKTMFFFLIQTEYGDVFKVTLDHNGDHVSELKVKYFDTIPVASSICVLKLGFLFSASEFGNHGLYQFQAIGEEPDVESSSSNLMETEEGFQPVFFQPRRLKNLVRIDQVESLMPLMDMKVLNIFEEETPQIFSLCGRGPRSSLRILRPGLAITEMAVSQLPGQPSAVWTVKKNVSDEFDAYIVVSFTNATLVLSIGEQVEEVNDSGFLDTTPSLAVSLIGDDSLMQVHPNGIRHIREDGRINEWRTPGKRSIVKVGYNRLQVVIALSGGELIYFEADMTGQLMEVEKHEMSGDVACLDIAPVPEGRKRSRFLAVGSYDNTVRILSLDPDDCLQILSVQSVSSAPESLLFLEVQASIGGDDGADHPANLFLNSGLQNGVLFRTVVDMVTGQLSDSRSRFLGLKPPKLFSISVRGRSAMLCLSSRPWLGYIHRGHFHLTPLSYETLEFAAPFSSDQCAEGVVSVAGDALRIFMIDRLGETFNETVVPLRYTPRKFVLHPKRKLLVIIESDQGAFTAEEREAARKECFEAGGVGENGNGNADQMENGADDEDKEDPLSDEQYGYPKAESEKWVSCIRVLDPKTATTTCLLELQDNEAAYSVCTVNFHDKEYGTLLAVGTVKGMQFWPKKNLVAGFIHIYRFVEDGKSLELLHKTQVEGVPLALCQFQGRLLAGIGPVLRLYDLGKKRLLRKCENKLFPNTIISIQTYRDRIYVGDIQESFHYCKYRRDENQLYIFADDCVPRWLTASHHVDFDTMAGADKFGNVYFVRLPQDLSEEIEEDPTGGKIKWEQGKLNGAPNKVDEIVQFHVGDVVTCLQKASMIPGGSESIMYGTVMGSIGALHAFTSRDDVDFFSHLEMHMRQEYPPLCGRDHMAYRSAYFPVKDVIDGDLCEQFPTLPMDLQRKIADELDRTPAEILKKLEDARNKII", "length": 1214 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P0DKL6-1", "protein_name": "Spliceosome-associated protein 130 B", "gene_name": "SAP130B", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MYLYSLTLQQATGIVCAINGNFSGGKTQEIAVARGKILDLLRPDENGKIQTIHSVEVFGAIRSLAQFRLTGAQKDYIVVGSDSGRIVILEYNKEKNVFDKVHQETFGKSGCRRIVPGQYVAVDPKGRAVMIGACEKQKLVYVLNRDTTARLTISSPLEAHKSHTICYSLCGVDCGFDNPIFAAIELDYSEADQDPTGQAASEAQKHLTFYELDLGLNHVSRKWSNPVDNGANMLVTVPGGADGPSGVLVCAENFVIYMNQGHPDVRAVIPRRTDLPAERGVLVVSAAVHKQKTMFFFLIQTEYGDVFKVTLDHNGDHVSELKVKYFDTIPVASSICVLKLGFLFSASEFGNHGLYQFQAIGEEPDVESSSSNLMETEEGFQPVFFQPRRLKNLVRIDQVESLMPLMDMKVLNIFEEETPQIFSLCGRGPRSSLRILRPGLAITEMAVSQLPGQPSAVWTVKKNVSDEFDAYIVVSFTNATLVLSIGEQVEEVNDSGFLDTTPSLAVSLIGDDSLMQVHPNGIRHIREDGRINEWRTPGKRSIVKVGYNRLQVVIALSGGELIYFEADMTGQLMEVEKHEMSGDVACLDIAPVPEGRKRSRFLAVGSYDNTVRILSLDPDDCLQILSVQSVSSAPESLLFLEVQASIGGDDGADHPANLFLNSGLQNGVLFRTVVDMVTGQLSDSRSRFLGLKPPKLFSISVRGRSAMLCLSSRPWLGYIHRGHFHLTPLSYETLEFAAPFSSDQCAEGVVSVAGDALRIFMIDRLGETFNETVVPLRYTPRKFVLHPKRKLLVIIESDQGAFTAEEREAARKECFEAGGVGENGNGNADQMENGADDEDKEDPLSDEQYGYPKAESEKWVSCIRVLDPKTATTTCLLELQDNEAAYSVCTVNFHDKEYGTLLAVGTVKGMQFWPKKNLVAGFIHIYRFVEDGKSLELLHKTQVEGVPLALCQFQGRLLAGIGPVLRLYDLGKKRLLRKCENKLFPNTIISIQTYRDRIYVGDIQESFHYCKYRRDENQLYIFADDCVPRWLTASHHVDFDTMAGADKFGNVYFVRLPQDLSEEIEEDPTGGKIKWEQGKLNGAPNKVDEIVQFHVGDVVTCLQKASMIPGGSESIMYGTVMGSIGALHAFTSRDDVDFFSHLEMHMRQEYPPLCGRDHMAYRSAYFPVKDVIDGDLCEQFPTLPMDLQRKIADELDRTPAEILKKLEDARNKII", "length": 1214 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P0DML3-1", "protein_name": "Chorionic somatomammotropin hormone 2", "gene_name": "CSH2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAGSRTSLLLAFALLCLPWLQEAGAVQTVPLSRLFDHAMLQAHRAHQLAIDTYQEFEETYIPKDQKYSFLHDSQTSFCFSDSIPTPSNMEETQQKSNLELLRISLLLIESWLEPVRFLRSMFANNLVYDTSDSDDYHLLKDLEEGIQTLMGRLEDGSRRTGQILKQTYSKFDTNSHNHDALLKNYGLLYCFRKDMDKVETFLRMVQCRSVEGSCGF", "length": 217 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DMV2-1", "protein_name": "Cancer/testis antigen family 45 member A9", "gene_name": "CT45A9", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTDKTEKVAVDPETVFKRPRECDSPSYQKRQRMALLARKQGAGDSLIAGSAMSKEKKLMTGHAIPPSQLDSQIDDFTGFSKDRMMQKPGSNAPVGGNVTSSFSGDDLECRETAFSPKSQQEINADIKRQLVKELRCVGQKYEKIFEMLEGVQGPTAVRKRFFESIIKEAARCMRRDFVKHLKKKLKRMI", "length": 189 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DOV1-1", "protein_name": "Interferon-activable protein 211", "gene_name": "Ifi211", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVNEYKRIVLLRGLECINKHYFSLFKSLLARDLNLERDNQEQYTTIQIANMMEEKFPADSGLGKLIEFCEEVPALRKRAEILKKERSEVTGETSLEKNGQEAGPATPTSTTSHMLASERGETSATQEETSTAQAGTSTAQAGTSTAQAGTSTAQKRKSMREEETGVKKSKAAKEPDQPPCCEEPTAMCQSPILHSSSSASSNILSAKNQKSQPQNQNIPRGAVLHSEPLTVMVLTATDPFEYESPEHEVKNMFHATVATVSQYFHVKVFNIDLKEKFTKNNFITISNYFESKGILEINETSSVLEAAPKQMIEVPNCITRNANASPKICDIQKGTSGTVFYGVFTLHKKKVKTQNTSYEIKDGSGSIEVVGSGQWHNINCKEGDKLHLFCFHLKRERGQPKLVCGDHSFVKVTKAGKKKEASTVQ", "length": 425 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P0DTA3-1", "protein_name": "Speedy protein E11", "gene_name": "SPDYE11", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGQILGKIMMSHQPQPQEERSPQRSTSGYPLQEVVDDEVSGPSAPGVDPSPPRRSLGWKRKRECLDESDDEPEKELAPEPEETWVAETLCGLKMKAKRRRVSLVLPEYYEAFNRLLEDPVIKRLLAWDKDLRVSDKYLLAMVIAYFSRAGLPSWQYQRIHFFLALYLANDMEEDDEAPKQNIFYFLYEETRSHIPLLSELWFQLCRYMNPRARKNCSQIALFRKYRFHFFCSMRCRAWVSLEELEEIQAYDPEHWVWARDRAHLS", "length": 265 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DUD3-1", "protein_name": "Speedy protein E14", "gene_name": "SPDYE14", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGQILGKIMMSHQPQPQEERSPQRSTSGYPLQEVVDDEVLGPSAPGVDPSPPRRSLGWKRKRECLDESDDEPEKELAPEPEETWVAETLCGLKMKAKRRRVSLVLPEYYEAFNRLLEDPVIKRLLAWDKDLRVSDKYLLAMVIAYFSRAGLPSWQYQRIHFFLALYLANDMEEDDEAPKQNIFYFLYEETRSHIPLLSELWFQLCRYMNPRARKNCSQIALFRKYRFHFFCSMRCRAWVSLEELEEIQAYDPEHWVWARDRAHLS", "length": 265 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DUD4-1", "protein_name": "Speedy protein E15", "gene_name": "SPDYE15", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGQILGKIMMSHQPQPQEERSPQRSTSGYPLQEVVDDEVLGPSAPGVDPSPPRRSLGWKRKRECLDESDDEPEKELAPEPEETWVAETLCGLKMKAKRRRVSLVLPEYYEAFNRLLEDPVIKRLLAWDKDLRVSDKYLLAMVIAYFSRAGLPSWQYQRIHFFLALYLANDMEEDDEAPKQNIFYFLYEETRSHIPLLSELWFQLCRYMNPRARKNCSQIALFRKYRFHFFCSMRCRAWVSLEELEEIQAYDPEHWVWARDRAHLS", "length": 265 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DW11-1", "protein_name": "TATA-box-binding protein-associated factor 11-like protein 6", "gene_name": "TAF11L6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METGRQTGVSAEMLAMPRGLKGSKKDGIPEDLDGNLEAPRDQEGELRSEDVMDLTEGDSEASASAPPAAKRRKTHTKGKKESKPTVDAEEAQRMTTLLSAMSEEQLSRYEVCRRSAFPRARVAGLMRAITGSSVSENAAIAMAGIAKLFVGEVVEEALDVCEMWGETPPLQPKHLREAVRRLKPKGLFPNSNCKRIMF", "length": 198 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DW12-1", "protein_name": "TATA-box-binding protein-associated factor 11-like protein 7", "gene_name": "TAF11L7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METGRQTGVSAEMLAMPRGLKGSKKDGIPEDLDGNLEAPRDQEGELRSEDVMDLTEGDSEASASAPPAAKRRKTHTKGKKESKPTVDAEEAQRMTTLLSAMSEEQLSRYEVCRRSAFPRARVAGLMRAITGSSVSENAAIAMAGIAKLFVGEVVEEALDVCEMWGETPPLQPKHLREAVRRLKPKGLFPNSNCKRIMF", "length": 198 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DW13-1", "protein_name": "TATA-box-binding protein-associated factor 11-like protein 8", "gene_name": "TAF11L8", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METGRQTGVSAEMLAMPRGLKGSKKDGIPEDLDGNLEAPRDQEGELRSEDVMDLTEGDSEASASAPPAAKRRKTHTKGKKESKPTVDAEEAQRMTTLLSAMSEEQLSRYEVCRRSAFPRARVAGLMRAITGSSVSENAAIAMAGIAKLFVGEVVEEALDVCEMWGETPPLQPKHLREAVRRLKPKGLFPNSNCKRIMF", "length": 198 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DW14-1", "protein_name": "TATA-box-binding protein-associated factor 11-like protein 10", "gene_name": "TAF11L10", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METGRQTGVSAEMLAMPRGLKGSKKDGIPEDLDGNLEAPRDQEGELRSEDVMDLTEGDSEASASAPPAAKRRKTHTKGKKESKPTVDAEEAQRMTTLLSAMSEEQLSRYEVCRRSAFPRARVAGLMRAITGSSVSENAAIAMAGIAKLFVGEVVEEALDVCEMWGETPPLQPKHLREAVRRLKPKGLFPNSNCKRIMF", "length": 198 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P11588-1", "protein_name": "Major urinary protein 1", "gene_name": "Mup1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMLLLLCLGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILASDKREKIEDNGNFRLFLEQIHVLENSLVLKFHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAQLCEKHGILRENIIDLSNANRCLQARE", "length": 180 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P11589-1", "protein_name": "Major urinary protein 2", "gene_name": "Mup2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMLLLLCLGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILASDKREKIEDNGNFRLFLEQIHVLEKSLVLKFHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAKLCEEHGILRENIIDLSNANRCLQARE", "length": 180 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P13255-1", "protein_name": "Glycine N-methyltransferase", "gene_name": "Gnmt", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVDSVYRTRSLGVAAEGIPDQYADGEAARVWQLYIGDTRSRTAEYKAWLLGLLRQHGCHRVLDVACGTGVDSIMLVEEGFSVTSVDASDKMLKYALKERWNRRKEPAFDKWVIEEANWLTLDKDVPAGDGFDAVICLGNSFAHLPDSKGDQSEHRLALKNIASMVRPGGLLVIDHRNYDYILSTGCAPPGKNIYYKSDLTKDITTSVLTVNNKAHMVTLDYTVQVPGAGRDGAPGFSKFRLSYYPHCLASFTELVQEAFGGRCQHSVLGDFKPYRPGQAYVPCYFIHVLKKTG", "length": 293 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P13675-1", "protein_name": "Y-linked testis-specific protein 1", "gene_name": "Ssty1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLMKKRRRKSSSNTLRNIVSCRISHSWKEGNEPVTQWKAIVLDQLPTNPSLYFVKYDGIDSIYVLELYSDDRILNLKVLPPIVVFPQVRDAHLARALVGRAVQHKFERKDGSEVNWRGVVLAQVPIMKDLFYITYKKDPALYAYQLLDDYKEGNLHMIPDTPPAEERSGDDSDVLIGNWVEYTRKDGSKKFGKVVYQVLANPSVYFIKFHGDIHIYVYTMVPKILEVEKS", "length": 232 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P15515-1", "protein_name": "Histatin-1", "gene_name": "HTN1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKFFVFALVLALMISMISADSHEKRHHGYRRKFHEKHHSHREFPFYGDYGSNYLYDN", "length": 57 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P16374-1", "protein_name": "Zinc finger protein 60", "gene_name": "Zfp60", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MANSSSQHMVCGSVTFRDVAVDFSQEEWACLDATQKVLYRNIMLETYSNLVAVVGRCIPKPDLIVLLEPEKEPWMAVKKETGRPSQGLETGFEAENRSPKNHVYNKKLPKQTIQQLSKTSDVQGVSVSNGPGYSVIKEPQNYQEGDANRNITNKKEMSTYTSKTLAHNKEKPYKCKDCGKCFGCKSNLHQHESIHTGEKPYECKDCGKTFRLPQMLSRHQKSHSDERPFECNICGKSFHLPTLLQYHKNIHTGLKPFECEECGKSFKSFNRISTLFQHRTIHAGMKPYKCNVCGKAFNRRSNLLQHQKIHSEDRPFHCKVCGKAFTVLAQLTRHENIHTEDKSFECKQCGKIFSNGSYLLRHYDTHTNEKPFECNICGKAFRLHLYLSEHQKTHTDEKPFKCKLCESAFRRKYQLSEHQRIHTDGKPYQCKDCWEFFRRRSNFIEHQSIHTGKKPFECKDCGKVFRLNIHLIRHQRFHSDEKPFECKECGKAFHFSSQLNNHKTSHTGQTPFECKECGKSFKRVSSLVEHRIIHSGVKPYKCNACGRAFNRRSNLMQHEKIHSDERPFECKDCGKAFTVLAQLTRHQTIHNGKKSYECEQCGSAFRLPYQLTQHQRIHYDVKPFQCKECGRAFVRSTGLRIHERIHTGEKPFQCKECGEAFQYHYQFLGHFRIHTGKNPYECSECGKYFTYGRDLKVHQSIHNLEKP", "length": 707 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P20816-1", "protein_name": "Cytochrome P450 4A2", "gene_name": "Cyp4a2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGFSVFSPTRSLDGVSGFFQGAFLLSLFLVLFKAVQFYLRRQWLLKALEKFPSTPSHWLWGHNLKDREFQQVLTWVEKFPGACLQWLSGSTARVLLYDPDYVKVVLGRSDPKPYQSLAPWIGYGLLLLNGKKWFQHRRMLTPAFHYDILKPYVKIMADSVSIMLDKWEKLDDQDHPLEIFHYVSLMTLDTVMKCAFSHQGSVQLDVNSRSYTKAVEDLNNLIFFRVRSAFYGNSIIYNMSSDGRLSRRACQIAHEHTDGVIKTRKAQLQNEEELQKARKKRHLDFLDILLFAKMEDGKSLSDEDLRAEVDTFMFEGHDTTASGISWVFYALATHPEHQERCREEVQSILGDGTSVTWDHLDQMPYTTMCIKEALRLYSPVPSVSRELSSPVTFPDGRSIPKGIRVTILIYGLHHNPSYWPNPKVFDPSRFSPDSPRHSHAYLPFSGGARNCIGKQFAMNELKVAVALTLLRFELLPDPTRIPVPMPRLVLKSKNGIHLRLKKLR", "length": 504 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P21571-1", "protein_name": "ATP synthase peripheral stalk subunit F6, mitochondrial", "gene_name": "Atp5pf", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTVQRIFRLSSVLRSAVSVHLRRNIGVTAVAFNKELDPVQKLFLDKIREYKAKRLASGGPVDTGPEYQQEVDRELFKLKQMYGKGEMDKFPTFNFEDPKFEVLDKPQS", "length": 108 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P22237-1", "protein_name": "NADH-ubiquinone oxidoreductase subunit 9", "gene_name": "nad9", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKDYKNELKVKINLGEHLRLSIPGLVKKIMYKTHYLEIQVEKEKMLTVLKYLKEASKYQCNMLLDIVCVDCLNIEEIKIGRFKLIYVLNSIYNNTRVHLSTYVENNGIIETTSGLFESSVWLEREIWDMFGIYFEKHPDLRRILTDYGFVGYPLKKDFPITGYLEVYYDVNDKKIIYKPIELMQEYRNYNFGAVWGDYERKVYLENIIK", "length": 209 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "P22283-1", "protein_name": "Cystatin-related protein 2", "gene_name": "Crp2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MYKTLCGTQLLLAIFVLFLNFSHATAKGTRGPMEIFKKNFMEKNKLNDVYDIFKFLYNKFSHDTYLSNIKNQSFTMNTWGFGEIEVVKTKCRKIDSDFYKCSFQWEFCNIKRTPGVTIYYITLPGSVRCRKLLSKLVNCPFEEQTEQLKREICYFQLYPDYIEQNIRSVRFNCYTK", "length": 176 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P23266-1", "protein_name": "Olfactory receptor 1f45", "gene_name": "Or1f45", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSTNQSSVTEFLLLGLSRQPQQQQLLFLLFLIMYLATVLGNLLIILAIGTDSRLHTPMYFFLSNLSFVDVCFSSTTVPKVLANHILGSQAISFSGCLTQLYFLAVFGNMDNFLLAVMSYDRFVAICHPLHYTTKMTRQLCVLLVVGSWVVANMNCLLHILLMARLSFCADNMIPHFFCDGTPLLKLSCSDTHLNELMILTEGAVVMVTPFVCILISYIHITCAVLRVSSPRGGWKSFSTCGSHLAVVCLFYGTVIAVYFNPSSSHLAGRDMAAAVMYAVVTPMLNPFIYSLRNSDMKAALRKVLAMRFPSKQ", "length": 313 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P24049-1", "protein_name": "Large ribosomal subunit protein uL22", "gene_name": "Rpl17", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVRYSLDPENPTKSCKSRGSNLRVHFKNTRETAQAIKGMHIRKATKYLKDVTLKKQCVPFRRYNGGVGRCAQAKQWGWTQGRWPKKSAEFLLHMLKNAESNAELKGLDVDSLVIEHIQVNKAPKMRRRTYRAHGRINPYMSSPCHIEMILTEKEQIVPKPEEEVAQKKKISQKKLKKQKLMARE", "length": 184 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P24868-1", "protein_name": "G2/mitotic-specific cyclin-1", "gene_name": "CLB1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSRSLLVENSRTINSNEEKGVNESQYILQKRNVPRTILGNVTNNANILQEISMNRKIGMKNFSKLNNFFPLKDDVSRADDFTSSFNDSRQGVKQEVLNNKENIPEYGYSEQEKQQCSNDDSFHTNSTALSCNRLIYSENKSISTQMEWQKKIMREDSKKKRPISTLVEQDDQKKFKLHELTTEEEVLEEYEWDDLDEEDCDDPLMVSEEVNDIFDYLHHLEIITLPNKANLYKHKNIKQNRDILVNWIIKIHNKFGLLPETLYLAINIMDRFLCEEVVQLNRLQLVGTSCLFIASKYEEIYSPSIKHFAYETDGACSVEDIKEGERFILEKLDFQISFANPMNFLRRISKADDYDIQSRTLAKFLMEISIVDFKFIGILPSLCASAAMFLSRKMLGKGTWDGNLIHYSGGYTKAKLYPVCQLLMDYLVGSTIHDEFLKKYQSRRFLKASIISIEWALKVRKNGYDIMTLHE", "length": 471 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P25389-1", "protein_name": "Probable serine/threonine-protein kinase KCC4", "gene_name": "KCC4", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MTVANTETHSAAKPSSTIGPWKLGETLGFGSTGKVQLAQHERTGHRTAVKVISKSIFNNNGNHSNDDSVLPYNIEREIVIMKLLSHPNVLSLYDVWETNNNLYLILEYAEKGELFNLLVDHGPLPEREAINCFRQIIIGISYCHALGIVHRDLKPENLLLDSFYNIKIADFGMAALQTDADLLETSCGSPHYAAPEIVSGLPYEGFASDVWSCGVILFALLTGRLPFDEENGNVRDLLLKVQKGQFEMPNDTEISRDAQDLIGKILVVDPRQRIKIRDILSHPLLKKYQTIKDSKSIKDLPRENTYLYPLADSNNHTSASIDDSILQNLVVLWHGRHADDIVSKLKENGTNKEKILYALLYRFKLDSVRGSNKKNRNKIKKTKKNKRSSTLSSSSSLLLNNRSIQSTPRRRTSKRHSREFSSSRKRSSFLLSSNPTDSSPIPLRSSKRITHINVASANTQATPSGVPNPHKRNSKKRSSKRLSYMPNTKRSSLTSKSLSNFTNLIDDDDWEYIEKDAKRTSSNFATLIDEIFEPEKFELAKREKAELQRKVQEAKRQSVNAQKINEDEFGSEVSDGMKELKKINDKVSSPLINYEFSQQELLQDIDTLLTNRYQLSSYTRPISRLDPGLTPVTETLPNNLKEKTALLQDTEKKIIETIRRSKFLGSLLNVRGGLSPGKSELAPIEESPIVSTTPLIYNDRMEPRRISDVEVPHFTRKSKHFTTANNRRSVLSLYAKDSIKDLNEFLIKEDPDLPPQGSTDNESRSEDPEIAESITDSRNIQYDEDDSKDGDNVNNDNILSDFPQGVGISQEYDMKDKNPNQSPISKSAEPTLVVKLPSLSSFQGKNASGLGLYQREPSKVTLPSLTSNNSSVGENIEDGAEKGTESEKIAASLSDDDLKEDNDKKDNDTVNAPTTVKKPPNSVLLKKFSKGKILELEIHAKIPEKRLYEGLHKLLEGWKQYGLKNLVFNITNMIITGKLVNDSILFLRSTLFEIMVLPNGDGRSLIKFNKKTGSTKTLTKLATEIQIILQKEGVLDK", "length": 1037 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P28312-1", "protein_name": "Alpha-defensin 5", "gene_name": "Defa5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTFVLLSALVLLAFQVQADPIHKTDEETNTEEQPGEEDQAVSISFGGQEGSALHEELSKKLICYCRIRGCKRRERVFGTCRNLFLTFVFCCS", "length": 93 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P28742-1", "protein_name": "Kinesin-like protein KIP1", "gene_name": "KIP1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MARSSLPNRRTAQFEANKRRTIAHAPSPSLSNGMHTLTPPTCNNGAATSDSNIHVYVRCRSRNKREIEEKSSVVISTLGPQGKEIILSNGSHQSYSSSKKTYQFDQVFGAESDQETVFNATAKNYIKEMLHGYNCTIFAYGQTGTGKTYTMSGDINILGDVQSTDNLLLGEHAGIIPRVLVDLFKELSSLNKEYSVKISFLELYNENLKDLLSDSEDDDPAVNDPKRQIRIFDNNNNNSSIMVKGMQEIFINSAHEGLNLLMQGSLKRKVAATKCNDLSSRSHTVFTITTNIVEQDSKDHGQNKNFVKIGKLNLVDLAGSENINRSGAENKRAQEAGLINKSLLTLGRVINALVDHSNHIPYRESKLTRLLQDSLGGMTKTCIIATISPAKISMEETASTLEYATRAKSIKNTPQVNQSLSKDTCLKDYIQEIEKLRNDLKNSRNKQGIFITQDQLDLYESNSILIDEQNLKIHNLREQIKKFKENYLNQLDINNLLQSEKEKLIAIIQNFNVDFSNFYSEIQKIHHTNLELMNEVIQQRDFSLENSQKQYNTNQNMQLKISQQVLQTLNTLQGSLNNYNSKCSEVIKGVTEELTRNVNTHKAKHDSTLKSLLNITTNLLMNQMNELVRSISTSLEIFQSDSTSHYRKDLNEIYQSHQQFLKNLQNDIKSCLDSIGSSILTSINEISQNCTTNLNSMNVLIENQQSGSSKLIKEQDLEIKKLKNDLINERRISNQFNQQLAEMKRYFQDHVSRTRSEFHDELNKCIDNLKDKQSKLDQDIWQKTASIFNETDIVVNKIHSDSIASLAHNAENTLKTVSQNNESFTNDLISLSRGMNMDISSKLRSLPINEFLNKISQTICETCGDDNTIASNPVLTSIKKFQNIICSDIALTNEKIMSLIDEIQSQIETISNENNINLIAINENFNSLCNFILTDYDENIMQISKTQDEVLSEHCEKLQSLKILGMDIFTAHSIEKPLHEHTRPEASVIKALPLLDYPKQFQIYRDAENKSKDDTSNSRTCIPNLSTNENFPLSQFSPKTPVPVPDQPLPKVLIPKSINSAKSNRSKTLPNTEGTGRESQNNLKRRFTTEPILKGEETENNDILQNKKLHQ", "length": 1111 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P29314-1", "protein_name": "Small ribosomal subunit protein uS4", "gene_name": "Rps9", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPVARSWVCRKTYVTPRRPFEKSRLDQELKLIGEYGLRNKREVWRVKFTLAKIRKAARELLTLDEKDPRRLFEGNALLRRLVRIGVLDEGKMKLDYILGLKIEDFLERRLQTQVFKLGLAKSIHHARVLIRQRHIRVRKQVVNIPSFIVRLDSQKHIDFSLRSPYGGGRPGRVKRKNAKKGQGGAGAGDDEEED", "length": 194 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P33579-1", "protein_name": "Prolactin-8A5", "gene_name": "Prl8a5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MELALSQPSFFGTLLMLVVSNLLLWEKAASIPACMVEDGGCWDPLREAFNSATQRAETLRNLSDQLYVEFFQNQFSSRQFADLSSQLIRKDETVLKAGTYCHSNRAKPKSRGVNIDIEEYLKMSINFCGFMDQPLFHLVIELSAMEGVPETILSKAKDLEENNRQLLDDLRWILTKVFPTAEIKEEFPSWDYLSFLKSSNKNHKFLAIFNLSSCLDYDTQVHYTLSQILNCLITGKDC", "length": 238 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P36006-1", "protein_name": "Myosin-3", "gene_name": "MYO3", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MAVIKKGARRKDVKEPKKRSAKIKKATFDANKKKEVGISDLTLLSKISDESINENLKKRFKNGIIYTYIGHVLISVNPFRDLGIYTNAVLESYKGKNRLEVPPHVFAIAESMYYNLKSYNENQCVIISGESGAGKTEAAKRIMQYIAAASNSHSESIGKIKDMVLATNPLLESFGCAKTLRNNNSSRHGKYLEIKFNSQFEPCAGNITNYLLEKQRVVGQIKNERNFHIFYQFTKGASDTYKQMFGVQMPEQYIYTAAAGCTTADTIDDVKDYEGTLEAMRTIGLVQEEQDQIFRMLAAILWIGNISFIENEEGNAQVGDTSVTDFVAYLLQVDASLLVKCLVERIMQTSHGMKRGSVYHVPLNPVQATAVRDALAKAIYNNLFDWIVDRVNVSLQAFPGADKSIGILDIYGFEIFEHNSFEQICINYVNEKLQQIFIQLTLKAEQETYEREKIKWTPIKYFDNKVVCDLIEAKNPPGILAAMNDSIATAHADSNAADQAFAQRLNLFNSNPYFELRANKFVIKHYAGDVTYDINGITDKNKDQLQKDLIELIGTTTNTFLSTIFPDDVDKDSKRRPPTAGDKIIKSANELVETLSKAEPSYIRTIKPNQTKSPNDYDDHQVLHQVKYLGLQENVRIRRAGFAYRQTFEKFVERFYLLSPDCSYAGDYTWDGDTLEAVKLILRDAMIPEKEFQLGVTSVFIKTPESLFALEDMRDKYWYNMAARIQRAWRRFLQRRIDAAIKIQRTIREKKGGNKYVKLRDYGTKLLAGKKERRSMSLLGYRAFMGDYLSCNESKTKGSYIRRQVGIKDKVVFSIKGECLHSKFGRSAQRLKKVFILTKKTFYIIGQTREQNAMKYTQDYKIDVGKIKQVSLTNLQDDWMGVILVNSTQSDPLINTPFKTELMTRLKKLNEKIMIKVGPTIEYHKQPNKLHTVRSKISDSAPKYGDIYKSSTIYVRRGHPANSKSNKKPKNPGGLSGKPIKSKKSKHKSTHKHTHSHRSHRDAAKKQPLPSQKPVNPLSLAATAAQAAYNPKPDKTVPIKSSAIPAAKVSSKHSSKPSSKEKVAVKKASSSHKSSSAKQNQVSMPPSKGVEKNKEPLKETTATATANIPIPPPPPPMGQPKDPKFEAAYDFPGSGSSSELPLKKGDIVFISRDEPSGWSLAKLLDGSKEGWVPTAYMTPYKDTRNTVPVAATGAVNDVTNQKSSQIDNTISSAQEGVQFGSATVGPTSDNQSNPVGTFSDGLASALAARANKMRAESADDDDNDDGDDDDDW", "length": 1272 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P36046-1", "protein_name": "Mitochondrial intermembrane space import and assembly protein 40", "gene_name": "MIA40", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MLRNLVVRNACRNRPSIQVARGLCRHQTRRLMASSPQFGRNSNQEKTAGFIMGILSMAGALYFIAPNRKPLFASRKVESDKTAEEELSSGGEQSPENEDDNNSKSDENGDDNDSKNDETEAGPQLGGDKIGASKVAEDGELVVLAEEDNKSSEDKDTDESKVSTKDDEQSNEDNATANNQKDENISSENSEENTSDKTLDNNAGSSEKKDPEHSDDEKSQQGQSDDKTTTEDNNGEEESSKKTVSDSENSAKQSESSDEEKEELRKQEEKQMGPTEEEVQHEGAYNPDTGEINWDCPCLGGMAHGPCGEEFKSAFSCFVYSEAEPKGIDCVEKFQHMQDCFRKYPEHYAEQLKETSDDEEPQDKVKVNTIESAPNVSSAKENAAKKAEQSDVKKEPLNEESKP", "length": 403 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P37106-1", "protein_name": "Signal recognition particle subunit SRP54 1", "gene_name": "SRP-54A", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MVLAELGGRITRAIQQMNNVTIIDEKVLNDFLNEITRALLQSDVSFGLVEKMQTNIKKIVNLDDLAAGHNKRLIIEQAIFKELCRMLDPGKPAFAPKKAKPSVVMFVGLQGAGKTTTCTKYAYYHQKKGYKAALVCADTFRAGAFDQLKQNATKAKIPFYGSYTESDPVKIAVEGVDRFKKEKCDLIIVDTSGRHKQAASLFEEMRQVAEATEPDLVIFVMDSSIGQAAFEQAEAFKETVSVGAVIITKMDGHAKGGGALSAVAATKSPVIFIGTGEHMDEFEVFDVKPFVSRLLGKGDWSGLVDKLQEVVPKDLQNELVENLSQGNFTLRSMYDQFQCSLRIPLNQLFSMLPGISAEMMPKGHGEESRVKMKRYMTMMDSMTNKELDSPNPKIFNESRIMRIARGSGRLVREVMEMLEEYKRIAKTMKGIKIPKNGDMSKVIPPQMLKQMGGMSGLQSLMKQMGSAKDMMGMFGGGGK", "length": 479 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P38150-1", "protein_name": "Inactive deaminase YBR284W", "gene_name": "", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MVQNNESVFFVECDSYKESPSTSPIRLDDLDGNDAVSDQGLAFDGDVGITSQARVRNPRAQIFEDSNTDVVLHLDDLDMVPLNTKFDMQMEMGSPMAMPAETPPPVEPLKTKDLAYSSLAHLPSYFFEQTHFRIDRKCLLEMSKLRRNYLTISKQDALSCPQLHSRVAGGYLKPVKEKLFGIRHFLDLEESNTVNLLQDGNYMTELFNSQINIPTFKEFREDFEWCLKIIRDRSLSRFSEKRLQYLVNKFPVFQHLHSKEEMRQSKKVPHKDFYNCRKIDLNLLLSGCFSQWQLTEFIWTKLRKEPDRVIHQAFNGSHITLSQLFKVNFEETGQFFNGLKIIDDSFLEWYKVIYLAKYHLVNDEMEIHTGSHGKQLRYYLIAKTFLEFDNYINGEYLAELLKTFLIKPQEESKYQLCQLSVDFQFYLHYDNSDVDNWWMVFANWLNHYNIFSNNIRWNIRISRIYPELYHTGKVKNFQEYLNLIFKPLFNAENYLHKSLGPILLKFLSQVSSIDLCIQDTDNYIWKNFTAVSCLPKDWTSGGDNPTISQYMYYVYVNLTKLNHIRQALHQNTFTLRSSCSPTSMNRTSQFSNTLNFTEHTEAILNNFLLACGGFLNAENLWNAPPSLVYLFYLSQIPMVVAPLNSIVDSKPTMLQEQAPTGLVLEPSKPYKKNPFMKFFEMGFKISLSSESILYNNSYTKEPIIEEYSVAASIYRLHSADLCELLRNSVITSGFSSTLKNKWLGVSLASHDYFVENTGFVDKWYDCKPNTSLEHNVPIIRRQYRSSTLAGEWRLIIA", "length": 797 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P40002-1", "protein_name": "Transcriptional regulator MIT1", "gene_name": "MIT1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MDIEPTFKGYIEDEDDALLILQATLDGKLKHIPRRPYEIERPYLIVSGSIFVFIEEISGIKRWTDGVSWSPSRISGKFLIYKELDKENAGSNANATSSGSTDSAVITDGTSGARNNPSSSKIKLPPLKNHQFDLPPTMGHSSFESEQDTSISPSNRSNLPLKYTGLVKKTISVKLKRPPFNSIENLHIVSYYSVKDIKQNCLVTPKASPFLKDVRPSQELIVAMGNTTLGNVKNNSTTTGNGPNNINNKSNSSTPLNTVISTNNNSANINAAGSNQFTSANKNYYYKNDESSGYPITQFAPALPSTTLMYTANPPYITQSPDNTNATGMNTHVNNNNNNSNNSSNSNNSNNNNNNNNNNNNNNNNNINNINNVNTNAGNGNNPNRFHNASFAYNTTGDFINPQQQGQISYPFYYTTIPINNPNYYTTQPPNPVTNASTNENQGYSTSSTQHPYYGHPTESQSASAAAGATGTPGTAENVLPVSSMQPLLHQANNNSASSATSTAPYPVYSMNVNVPYYNSSASAYKRAQENTTSNTNAEPSGATSTNSGTMLSNPAYANSQYTPSQVYYQGFPQYAMASAQNPSMYQHQHQHPLPTVYPIATPQQNIMSSGHTLSTIGSDPQHHHYQQEPNDHKNFAMGHANNNILNITNNDTMNNLNTNTSTTTQ", "length": 666 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P42222-1", "protein_name": "Enolase-related protein 3", "gene_name": "ERR3", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSITKVHARTVYDSRGNPTVEVEITTENGLFRAIVPSGASTGIHEAVELRDGNKSEWMGKGVTKAVSNVNSIIGPALIKSDLCVTNQKGIDELMISLDGTSNKSRLGANAILGVSLCVARAAAAQKGITLYKYIAELADARQDPFVIPVPFFNVLNGGAHAGGSLAMQEFKIAPVGAQSFAEAMRMGSEVYHHLKILAKEQYGPSAGNVGDEGGVAPDIDTAEDALDMIVKAINICGYEGRVKVGIDSAPSVFYKDGKYDLNFKEPNSDPSHWLSPAQLAEYYHSLLKKYPIISLEDPYAEDDWSSWSAFLKTVNVQIIADDLTCTNKTRIARAIEEKCANTLLLKLNQIGTLTESIEAANQAFDAGWGVMISHRSGETEDPFIADLVVGLRCGQIKSGALSRSERLAKYNELLRIEEELGDDCIYAGHRFHDGNKL", "length": 437 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P43356-1", "protein_name": "Melanoma-associated antigen 2", "gene_name": "MAGEA2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPLEQRSQHCKPEEGLEARGEALGLVGAQAPATEEQQTASSSSTLVEVTLGEVPAADSPSPPHSPQGASSFSTTINYTLWRQSDEGSSNQEEEGPRMFPDLESEFQAAISRKMVELVHFLLLKYRAREPVTKAEMLESVLRNCQDFFPVIFSKASEYLQLVFGIEVVEVVPISHLYILVTCLGLSYDGLLGDNQVMPKTGLLIIVLAIIAIEGDCAPEEKIWEELSMLEVFEGREDSVFAHPRKLLMQDLVQENYLEYRQVPGSDPACYEFLWGPRALIETSYVKVLHHTLKIGGEPHISYPPLHERALREGEE", "length": 314 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P43357-1", "protein_name": "Melanoma-associated antigen 3", "gene_name": "MAGEA3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPLEQRSQHCKPEEGLEARGEALGLVGAQAPATEEQEAASSSSTLVEVTLGEVPAAESPDPPQSPQGASSLPTTMNYPLWSQSYEDSSNQEEEGPSTFPDLESEFQAALSRKVAELVHFLLLKYRAREPVTKAEMLGSVVGNWQYFFPVIFSKASSSLQLVFGIELMEVDPIGHLYIFATCLGLSYDGLLGDNQIMPKAGLLIIVLAIIAREGDCAPEEKIWEELSVLEVFEGREDSILGDPKKLLTQHFVQENYLEYRQVPGSDPACYEFLWGPRALVETSYVKVLHHMVKISGGPHISYPPLHEWVLREGEE", "length": 314 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P43537-1", "protein_name": "Uncharacterized membrane protein YFL067W", "gene_name": "", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MESIILSIAIFIGVLLGTSVGAGSGSSISPDVDAGSGSRTSPDVDAGSGSRISAGVGTFSGSSTSPDVDAGSGSSTSPDVGAGSGSSISAGVGSRIGTGIGSRIGTGIGTGIGSRISTSIGSRISPDVGTSSGNRISTGVSTGISTTMNARVAVLITAAILSAPVTAIALLEARR", "length": 175 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P46162-1", "protein_name": "Beta-defensin 4", "gene_name": "DEFB4", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRLHHLLLAVLFLVLSAGSGFTQRVRNPQSCRWNMGVCIPFLCRVGMRQIGTCFGPRVPCCRR", "length": 63 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P46169-1", "protein_name": "Beta-defensin 11", "gene_name": "DEFB11", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRLHHLLLALLFLVLSAGSGISGPLSCRRNGGVCIPIRCPGPMRQIGTCFGRPVKCCRSW", "length": 60 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P47102-1", "protein_name": "ARF guanine-nucleotide exchange factor 1", "gene_name": "GEA1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MHDVPMETVLAVNPATMIVKECINLCSAMNKQSRDKSQTSVAALLGGGSDIFLSQSDSFVDSFHNLPTSSYHDPLISGLVQLRLKINDLKGLDSLNALELLKPFLEIVSASSVSGYTTSLALDSLQKVFTLKIINKTFNDIQIAVRETVVALTHCRFEASKQISDDSVLLKVVTLLRDIITSSFGDYLSDTIIYDVLQTTLSLACNTQRSEVLRKTAEVTIAGITVKLFTKLKLLDPPTKTEKYINDESYTDNNLKDDIIGTTTSDNDLSSTDDDSAVADDNKNEKPVQQVIREQENDEETAEKAENVEPNYGITVIKDYLGLLLSLVMPENRMKHTTSAMKLSLQLINAAIEISGDKFPLYPRLFSLISDPIFKSVLFIIQSSTQYSLLQATLQLFTSLVVILGDYLPMQIELTLRRIFEILEDTTISGDVSKQKPPAIRELIIEQLSILWIHSPAFFLQLFVNFDCNLDRSDLSIDFIKELTKFSLPAAAVNTSNNIPPICLEGVLSLIENIYNDLQRFDRAEFVKNQKEIDILKQRDRKTEFILCVETFNEKAKKGIQMLIEKGFIDSDSNRDIASFLFLNNGRLNKKTIGLLLCDPKKTSLLKEFIDLFDFKGLRVDEAIRILLTKFRLPGESQQIERIVEAFSSKYSADQSNDKVELEDKKAGKNGSESMTEDDIIHVQPDADSVFVLSYSIIMLNTDSHNPQVKDHMTFDDYSNNLRGCYNGKDFPRWYLHKIYTSIKVKEIVMPEEHHGNERWFEDAWNNLISSTSVMTEMQRDFTNPISKLAQIDILQYEKAIFSNVRDIILKTLFKIFTVASSDQISLRILDAISKCTFINYYFSFDQSYNDTVLHLGEMTTLAQSSAKAVELDVDSIPLVEIFVEDTGSKISVSNQSIRLGQNFKAQLCTVLYFQIIKEISDPSIVSTRLWNQIVQLILKLFENLLMEPNLPFFTNFHSLLKLPELPLPDPDISIRKAKMSRSLLSTFASYLKGDEEPSEEDIDFSIKAFECVKASHPLSSVFENNQLVSPKMIETLLSSLVIEKTSENSPYFEQELLFLLEISIILISEASYGQEFGALIADHMINISNLDGLSKEAIARLASYKMFLVSRFDNPRDILSDLIEHDFLVKNEIFNTKYYESEWGKQVINDLFTHLNDVKYNERALKNVKFWNFLRILISAKDRQFAVYTFLEKYIQNGDIFVDDGNFMNILSLLDEMSCAGAVGTKWEQNYENSVEDGCEAPESNPYRSIIDLSSRSINITADLLSTVGRSNSALNKNEIIAAIQGLAHQCLNPCDELGMQALQALENILLSRASQLRTEKVAVDNLLETGLLPIFELDEIQDVKMKRITSILSVLSKIFLGQLVEGVTSNETFLRVLNVFNKYVDDPTVERQLQELIISKREIEKE", "length": 1408 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P53563-1", "protein_name": "Bcl-2-like protein 1", "gene_name": "Bcl2l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSQSNRELVVDFLSYKLSQKGYSWSQFSDVEENRTEAPEETEPERETPSAINGNPSWHLADSPAVNGATGHSSSLDAREVIPMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAYQSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIASWMATYLNDHLEPWIQENGGWDTFVDLYGNNAAAESRKGQERFNRWFLTGMTVAGVVLLGSLFSRK", "length": 233 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P56840-1", "protein_name": "Protein TCL1B1", "gene_name": "Tcl1b1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAAAFDPLGPLPVYLVSVRLGIYEDEHHRVWIVANVETSHSSHGNRRRTHVTVHLWKLIPQQVIPFNPLNYDFLPTTWKLESRNIYWATDGTHWRLLDHSQLGDTEQLILMLVLG", "length": 116 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P56841-1", "protein_name": "Protein TCL1B2", "gene_name": "Tcl1b2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAAGFYPPRLLPQVLISTGPGFYEDEHHRLWMVAKLETCSHSPYCNKIETCVTVHLWQMTRYPQEPAPYNPMNYNFLPMTWRLASMNTYRGTDAMHWRLLNHSQVGDTVQLILMLE", "length": 117 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P56842-1", "protein_name": "Protein TCL1B3", "gene_name": "Tcl1b3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADSVHFPWMPFPPRFLVCTRDDIYEDENGRQWVVAKVETSRSPYGSRIETCITVHLQHMTTIPQEPTPQQPINNNSLPTMWRLESMNTYTGTDGTYWRLLDHSQMGDTLQLILDIVICEVD", "length": 122 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P56844-1", "protein_name": "Protein TCL1B4", "gene_name": "Tcl1b4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADSVRFPCMPFPPCFLVCTRDDIYEDEHGRQWVAAKVETSSHSPYCSKIETCVTVHLWQMTTLFQEPSPDSLKTFNFLPRTWRLESRNTYRGADAMHWRLVNHSQFYGTEELVLMLDSR", "length": 120 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P59528-1", "protein_name": "Taste receptor type 2 member 123", "gene_name": "Tas2r123", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSQKINYSHLFTFSITLYVEIVTGILGHGFIALVNIMDWVKRRRISSVDQILTALALTRFIYVLSMLICILLFMLCPHLPRRSEMLSAMGIFWVVNSHFSIWLTTCLGVFYFLKIANFSNSFFLYLKWRVKKVILIIILASLIFLTLHILSLGIYDQFSIAAYVGNMSYSLTDLTQFSSTFLFSNSSNVFLITNSSHVFLPINSLFMLIPFTVSLVAFLMLIFSLWKHHKKMQVNAKQPRDVSTMAHIKALQTVFSFLLLYAIYLLFLIIGILNLGLMEKIVILIFDHISGAVFPISHSFVLILGNSKLRQASLSVLPCLRCQSKDMDTMGL", "length": 333 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P61314-1", "protein_name": "Large ribosomal subunit protein eL15", "gene_name": "Rpl15", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGAYKYIQELWRKKQSDVMRFLLRVRCWQYRQLSALHRAPRPTRPDKARRLGYKAKQGYVIYRIRVRRGGRKRPVPKGATYGKPVHHGVNQLKFARSLQSVAEERAGRHCGALRVLNSYWVGEDSTYKFFEVILIDPFHKAIRRNPDTQWITKPVHKHREMRGLTSAGRKSRGLGKGHKFHHTIGGSRRAAWRRRNTLQLHRYR", "length": 204 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P62246-1", "protein_name": "Small ribosomal subunit protein uS8", "gene_name": "Rps15a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVRMNVLADALKSINNAEKRGKRQVLIRPCSKVIVRFLTVMMKHGYIGEFEIIDDHRAGKIVVNLTGRLNKCGVISPRFDVQLKDLEKWQNNLLPSRQFGFIVLTTSAGIMDHEEARRKHTGGKILGFFF", "length": 130 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P62425-1", "protein_name": "Large ribosomal subunit protein eL8", "gene_name": "Rpl7a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPKGKKAKGKKVAPAPAVVKKQEAKKVVNPLFEKRPKNFGIGQDIQPKRDLTRFVKWPRYIRLQRQRAILYKRLKVPPAINQFTQALDRQTATQLLKLAHKYRPETKQEKKQRLLARAEKKAAGKGDVPTKRPPVLRAGVNTVTTLVENKKAQLVVIAHDVDPIELVVFLPALCRKMGVPYCIIKGKARLGRLVHRKTCTTVAFTQVNSEDKGALAKLVEAIRTNYNDRYDEIRRHWGGNVLGPKSVARIAKLEKAKAKELATKLG", "length": 266 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P62802-1", "protein_name": "Histone H4", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG", "length": 103 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P62963-1", "protein_name": "Profilin-1", "gene_name": "Pfn1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGWNAYIDSLMADGTCQDAAIVGYKDSPSVWAAVPGKTFVSITPAEVGVLVGKDRSSFFVNGLTLGGQKCSVIRDSLLQDGEFTMDLRTKSTGGAPTFNVTVTMTAKTLVLLMGKEGVHGGLINKKCYEMASHLRRSQY", "length": 140 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P62982-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "Rps27a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGAKKRKKKSYTTPKKNKHKRKKVKLAVLKYYKVDENGKISRLRRECPSDECGAGVFMGSHFDRHYCGKCCLTYCFNKPEDK", "length": 156 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P70709-1", "protein_name": "Eosinophil cationic protein", "gene_name": "Rnase3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGLKLLESRLCLLLSLGLVLMLASCQPPTPSQWFEIQHIYNRAYPRCNDAMRHRNRFTGHCKDINTFLHTSFASVVGVCGNRNIPCGNRTYRNCHNSRYRVSITFCNLTTPARIYTQCRYQTTRSRKFYTVGCDPRTPRDSPMYPVVPVHLDRIF", "length": 155 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P81278-1", "protein_name": "Prolactin-releasing peptide", "gene_name": "Prlh", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALKTWLLCLLLLSLVLPGASSRAHQHSMETRTPDINPAWYTGRGIRPVGRFGRRRATPRDVTGLGQLSCLPLDGRTKFSQRG", "length": 83 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P83883-1", "protein_name": "Large ribosomal subunit protein eL42", "gene_name": "Rpl36a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVNVPKTRRTFCKKCGKHQPHKVTQYKKGKDSLYAQGKRRYDRKQSGYGGQTKPIFRKKAKTTKKIVLRLECVEPNCRSKRMLAIKRCKHFELGGDKKRKGQVIQF", "length": 106 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P83884-1", "protein_name": "Large ribosomal subunit protein eL42", "gene_name": "RPL36A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVNVPKTRRTFCKKCGKHQPHKVTQYKKGKDSLYAQGKRRYDRKQSGYGGQTKPIFRKKAKTTKKIVLRLECVEPNCRSKRMLAIKRCKHFELGGDKKRKGQVIQF", "length": 106 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P97876-1", "protein_name": "Basic leucine zipper transcriptional factor ATF-like 3", "gene_name": "Batf3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSQGPPAGGVLQSSVAAPGNQPQSPKDDDRKVRRREKNRVAAQRSRKKQTQKSDKLHEEHESLEQENSVLRREIAKLKEELRHLTEALKEHEKMCPLLLCPMNFVQLRPDPVASWSAHDAPDHPSFIWLGTLV", "length": 133 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q00729-1", "protein_name": "Histone H2B type 1-A", "gene_name": "H2bc1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPEVSAKGTTISKKGFKKAVTKTQKKEGRKRKRCRKESYSIYIYKVLKQVHPDTGISSKAMSIMNSFVTDIFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSSK", "length": 127 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q01534-1", "protein_name": "Testis-specific Y-encoded protein 1", "gene_name": "TSPY1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRPEGSLTYRVPERLRQGFCGVGRAAQALVCASAKEGTAFRMEAVQEGAAGVESEQAALGEEAVLLLDDIMAEVEVVAEEEGLVERREEAQRAQQAVPGPGPMTPESAPEELLAVQVELEPVNAQARKAFSRQREKMERRRKPHLDRRGAVIQSVPGFWANVIANHPQMSALITDEDEDMLSYMVSLEVGEEKHPVHLCKIMLFFRSNPYFQNKVITKEYLVNITEYRASHSTPIEWYPDYEVEAYRRRHHNSSLNFFNWFSDHNFAGSNKIAEILCKDLWRNPLQYYKRMKPPEEGTETSGDSQLLS", "length": 308 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q03764-1", "protein_name": "Ethanolamine kinase", "gene_name": "EKI1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MYTNYSLTSSDAMPRTYLVGTASPEMSKKKRQSANCDKPTRRVIHIIDTNEHSEVDLKNELPITCTNEDGEMTSSSWTSQTANDFLKLAYVNAKLDPSLPSQYFKQDIINVLQSLEIPGWSVPGSKESSLNKNLLTLTQIKGALTNVIYKIHYPNLPPLLMRIFGDSIDSVIDREYELKVIARLSFYDLGPKLEGFFENGRFEKYIEGSRTSTQADFIDRDTSIKIAKKLKELHCTVPLTHKEITDQPSCWTTFDQWIKLIDSHKEWVSNNVNISENLRCSSWNFFLKSFKNYKRWLYNDSAFTSKLLREDDKDSMINSGLKMVFCHNDLQHGNLLFKSKGKDDISVGDLTIIDFEYAGPNPVVFDLSNHLNEWMQDYNDVQSFKSHIDKYPKEEDILVFAQSYINHMNENHVKIASQEVRILYNLIIEWRPCTQLFWCLWALLQSGRLPQRPLIEGEKLMSEKAGLGDETHLMEHKNKENGKYDCSEDDSFNYLGFCKEKMSVFWGDLITLGVIDKDCPDIGKTDYLDTKLIF", "length": 534 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q04902-1", "protein_name": "Probable glutathione-independent glyoxalase SNO4", "gene_name": "SNO4", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MTPKRALISLTSYHGPFYKDGAKTGVFVVEILRSFDTFEKHGFEVDFVSETGGFGWDEHYLPKSFIGGEDKMNFETKNSAFNKALARIKTANEVNASDYKIFFASAGHGALFDYPKAKNLQDIASKIYANGGVIAAICHGPLLFDGLIDIKTTRPLIEGKAITGFPLEGEIALGVDDILRSRKLTTVERVANKNRAKYLAPIHPWDDYSITDGKLVTGVNANSSYSTTIRAINALYS", "length": 237 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q0D2J5-1", "protein_name": "Zinc finger protein 763", "gene_name": "ZNF763", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDPVACEDVAVNFTQEEWALLDISQRKLYREVMLETFRNLTSIGKKWKDQNIEYEYQNPRRNFRSLIEGNVNEIKEDSHCGETFTQVPDDRLNFQEKKASPEAKSCDNFVCGEVGIGNSSFNMNIRGDIGHKAYEYQDYAPKPYKCQQPKKAFRYHPSFRTQERNHTGEKPYACKECGKTFISHSGIRRRMVMHSGDGPYKCKFCGKAVHCLRLYLIHERTHTGEKPYECKQCVKSFSYSATHRIHERTHTGEKPYECQQCGKAFHSSSSFQAHKRTHTGGKPYECKQCGKSFSWCHSFQIHERTHTGEKPCECSKCNKAFRSYRSYLRHKRSHTGEKPYQCKECRKAFTYPSSLRRHERTHSAKKPYECKQCGKALSYKFSNTPKNALWRKTL", "length": 394 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q0WX57-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 24", "gene_name": "USP17L30", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEDDSLYLRGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSCETRVDLCDDLAPVARQLAPREKLPLSSRRPAAVGAGLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRALHNPGHVIQPSQALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRFSDVTGNKIAKNVQYPECLDMQPYMSQPNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQEGQWYKMDDAEVTASSITSVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRATQGELKRDHPCLQAPELDEHLVERATQESTLDHWKFLQEQNKTKPEFNVRKVEGTLPPDVLVIHQSKYKCGMKNHHPEQQSSLLNLSSSTPTHQESMNTGTLASLRGRARRSKGKNKHSKRALLVCQ", "length": 530 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q1LYG5-1", "protein_name": "Elongation factor 2a.1", "gene_name": "eef2a.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MENFNVDQIRATMDKKSNIRNMSVIGAFDHGKSTLTDWLVSEAGIVSSARAGETRFMDTRRDEQERCITIKSTAISIFYELAEKDLAFIKECKDGSGFLLNLIDSPGHVDFSSEVTAALRITDGALLVVDCVSGVCLQTETVLRQAIGERIKPVLMINKMDRALLELQLVPEELYQIFQRIVEKVNVTISTYAEDEKGPMGNVMIDPVIGNLAFGSGLHGWAFTLKQFAELYVKKFAGKAQLGPEEYIKKVEDMIKRLWGDSYFDSTTGKFSESATSPDGKKLPRTFVHLVLDPIFKVFDAIMNFKKEETVKLIEKMGIKLDVEDKEKEGKILLKAVMRCWLPAGEALLQMITIHLPSPVTAQIYRCELLYEGPGDDEAAMGIKNCDPKAPLMMYISKMIPTSDKGCFYAFGRVFSGCVSTGLNVRIMGPNFTPGKKDDLYLKPIQRTVLMMGRYVEPIEDVPCGNIVGLLGVDQFLVKTGTITTFTKAYNMRVMKFSVSPVVRVSVEVMDPADLPKLVEGLKHLAKSDPMLQCIIEDTGEHIIAGAGELHLEICLKDLEEDHACIPLKKSDPFASYRETVSDGSKQLCLAKTPNKHSRLFMKACPLADGLAEDIDKGRVTASQEMNARAQYLAENYKWEVTEARKIWCFGPEGTGPNILVDLTKRVQYLNEIKDSVIAGFQWATREGVLCAENMRGIRFDIHDATLTSTAIHRGPGQIIVATRRVLYGCQLTAEPRLSEPIYLVEMQCPESVIGNVYGELVRRRGVVFSESQVMGTPVYLLKAYLPVSESFGFTADLCANTSGQAFSQCVFDHWQILPGDPMDPTSKVAHIMADIRKSKGLDEAIPALHCYLD", "length": 854 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q1PEY5-1", "protein_name": "Probable 3-hydroxyisobutyryl-CoA hydrolase 2", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MASHSQVLVEEKSSVRILTFNRPKQLNALSFHMVSRLLQLFLAYEEDPSVKLVVLKGQGRAFSAGGDIPPIVRDILQGKLIRGAHYFKVGYTLNYVLSTYRKPQVSILNGIVMGGGAGLSTNGRFRIATENTVFAMPETALGLFPDVGASYFLSRLPGFFGEYVGLTGARLDGAEMLACGLATHFVPSISLTALEAELYKVGSSNQTFISTILDAYAEYPHLNQHSSYHRLDVIDRCFSKRTVEEIFSALEREVTQKPNDWLLATIQALEKASPSCLKISLRSIREGRLQGVGQCLIREYRMVCHVMKGDISKDFVEGCRAVLIDKDRNPKWQPRRLEDVTDSMVDQYFERVEDEEGWEDLKFPPRNNLPALAIAAKL", "length": 378 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q1ZXA5-1", "protein_name": "ADP-ribosylation factor-like protein DDB_G0292332", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDFIISFIKNLFGFLTIKKVMILGVENVGKTTLLYNIYKFYSENITTTTLSSLPIPIPTNGFNVESIVIEQVKFDIWDIGGKETNRICYRHYLTSEIDSIIFVFDSSDINSLEESKKEYQYLKNQISLKNVPFLLVANKQDLKQQTIEIDEILKTYFDKSSINETILMSQNNNDDLIKCINWIFSN", "length": 186 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q1ZXJ4-1", "protein_name": "Acetyl-coenzyme A transporter 1", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MLFTLLKRHFGNELNNIVWLVLLYLIQGIPIGLSFGTIPFLLHKHATYTQIGIFTISTYPYSLKLLWSPIVDSYFVQSFGRRKSWIVPIQILAGIVFITISFFIETLLEHAETKIIYITIVFFLLIFLMATQDIAVDAWALTILSKPYLHYASTCQTIGLNTGYFLSYTIFLTLSSPKFANKFLRSVPSEEGIITLPGYLQFWGILFIILSIYLAFFKDEESTTITTTTTRHDNYNNNNNDDKNKQVKSKIENESIESKSMRSSPSSLSPSLLSSPVKKQNKKNKQHISIDKKDITIIKENNENNEIIDNNNSNNNYDNGKKSIVQETYGMDISESDLTPKQVYYLLWKIITLPHIKILSILFIISKIVFQPNESALNLKLLEKGLRKEDIASFSLIQFPSIIIFSIISSKWVKNKPLTIWSNAYLVGVFFILVNMCSVFYFPNLNGGEISWSHFFLLLMISLFSSFSYNLMSVSQGSFFLKISDKSIGGTYVTLLNTIANFAGTYPKLFILMLIDKLTTSECIVNISNDNSSSSSSSSSLISTSSNNLTTTTTIIQEQQQQVIIHDNISKELCAEQNGKYRIERDGYYLVATGAIIYGVFIYFVLKRYLTPIEKLKL", "length": 618 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q23888-1", "protein_name": "Large ribosomal subunit protein uL2m", "gene_name": "mrpl2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MVLNWRGVKSRLYSGKRRIDGRNKGLIAIRSRGGALKRKYRYIEHYKQKWMDKWLFVMRIEYDPNRSAHIALCSILKEGIYFYVISIAKLEVGSLIITSALKLGTLQVGNTTKIKNIPEGLLINNIELIENSGSKISRAAGTSSLIIKKYNKKYSLVKLSSKECRLISNECYATIGTVSNIERKLKQNKKASYSRKRGIRPIVRGLAMNPVDHPHGGRTKGGVHWKSFSGKLAYNVSSRKKTKMTSRYIIIGHRKQKIMDKQIKNG", "length": 266 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q24113-1", "protein_name": "Protein no-on-transient A", "gene_name": "nonA-l", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MEGAVKKNSLNSSPLPQRQQRGNSTNKNLGKPTPPKLNAASDGNPAEKKARLGGNTQNGGGVAGGGGTGGGGGGGGATGGVEFSRNRNRGGNQNENRQGFQVANNSHQKQINESPKPAAGNVPAKNNELSAGGGGQNQPNHSNKGQGNQGDQGEQGNQGPNFRGRGGGPNQPNQNANQEQSNGYPGNQGDNKGGQGQRGAGGGKHQRGNRSRRSGGSGIMNSSMGGGGQRGEDFFIAQRLLDISGPTHELPPIELPTDNKFVGRNRLYVGNLTSDTTDDDLREMFKPYGEIGDIFSNPEKNFTFLRLDYYQNAEKAKRALDGSLRKGRVLRVRFAPNAIVRVTNLNQFVSNELLHQSFEIFGPIERAVICVDDRGKHTGEGIVEFAKKSSASACLRLCNEKCFFLTASLRPCLVEPMEVNNDNDGLPDKTLNKKSLEFRHERSVGPRFACLNSFEHEYGSRWKQLHDLFKSKQDSLKRELKMEEDKLEAQMEYARYEQETELLRQELKKRELDNERMKLEWEMREKQAEEIRKREEEYMHRYQNQLLRHEEDMRARQQENDLLMQAKKLNMILDQQEGFGGSNSGFEHFDSPFEVFGNNSNNSTMAGPGGPDNSDGNQHGHIDSWGHRRF", "length": 630 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q2PRK7-1", "protein_name": "Odorant receptor 106-10", "gene_name": "or80a10", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MANETFVKNVDSFIITGFDHLQNQKLLGSLILISYMFILLGNGINLCIISTDRHLHKPMYILICNLAVVDIMYSSTCSTTMISVLLAEIKTVSYYSCISRTYFFNLGDLTECMALTLMAIDRLIAINLPLRYHSFVTNSRILWLIFLTWIFSFAVIGFLTYVADTLPYCQPIIKYVFCSYSSLVRAACVDPEPYFAISTVYSMVTLCGLFPFILCTYAVLAYSVTKLANSSRKQMINTCLSHIIVLFSFYLPKIVYILLTRIGLVLTLTERNAVLIVSCFVSLLVNPTVYCIRTKGIRKRITDIFLYTQKITK", "length": 313 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q2YDJ5-1", "protein_name": "Uncharacterized protein CXorf66 homolog", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNLFIYVLLLSIWTSSCLDRNESNGSATAVTTHAEFKQTKLQELRRRLLIIVIGTLITGYMVSCTCLLHYSCDSEEAHTAAKDKKEDITIKASRSSKISFTDSKSPTAGLGDPERQSVVSRIDKSSGPSSPRKVPSSAEKLVRPSSQKKPSKPSAPKKVLGSPPQEKLHRTRSPKKAHRQAHAHKPVSQVSPSYPEKAIKSTWPPSLQCRAKPTKTPLPYPKNQSFPEQSSVDKLTKRQRYLKLKCPASAGRAEILSRPHPVKFCRCYKEKCLVCRAVSEPFITHVSDANKKHVPVPLFSRELKHFYKSYKKKQPKYNTLYGNMSDSDITTYNSDGESDREVIIMCNIKCKEDIYKNSRNN", "length": 361 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q3L180-1", "protein_name": "Alpha-defensin 26", "gene_name": "Defa26", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTLVLLSALFLLAFQVQADPIQNTDEETNTEVQPQEEDQAVSVSFGNPEGSDLQEESLRDLGCYCRKRGCTRRERINGTCRKGHLMYTLCCL", "length": 93 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q3TR54-1", "protein_name": "Gasdermin-C4", "gene_name": "Gsdmc4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGYSFDRASKDVVKKLQGRDLRPVECLSDATKFRLFHILQETPRSGWETEDIPVGFTLLDLLEPNFPVPEPEVSAPKPFIHVQSTDLEANLNVADIARGGVGYVGYGGYNIEVQSTSIPNPKLEILQNRKLLDKLPTFMKFCRMERKNLYVVTEAYEVSKDTMLTGLSSVNLLVKGFFKQLFKVRGKAGRSEKYSIPIPKGSVLAYKKQQLVIENNTCVILPSATKKKMTFPDRPLKLYDLPVTLRYQEEVIETGSWIDDIDPIGTIEEPANLNFMCLQHEVSEQTQLLAELSKDVQEVVFSSFLHMLSDRDVLYDLMKMLELNQLGHMDGPGGKILDELRKDSSTPHDVLKDLNLYLLQALLVLSDTQLCLLAQSVKMGLLPHQVELVKSILQTNFKYSSNTPFTLQPQLLAPLQGEGLAITYELLEECGLKMELNNPRSTWDLEAKMPLSALYGSLSFLQQLQKANSSSKPSLSPGYI", "length": 480 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q3U0I6-1", "protein_name": "Endoregulin", "gene_name": "Erln", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGQMVPPRSIQNEDFWKNPWDVGGLTVIGLFTSTFLLFVLFAVVFGYVEKAVFEEE", "length": 56 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q3URS2-1", "protein_name": "Zinc finger and SCAN domain containing protein 4F", "gene_name": "Zscan4f", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASQQAPAKDLQTNNLEFTPTDSSGVQWAEDISNSPSAQLNFSPSNNGCWATQELQSLWKMFNSWLQPEKQTKEQMISQLVLEQFLLTGHCKDKYALTEKWKASGSDMRRFMESLTDECLKPPVMVHVSMQGQEALFSENMPLKEVIKLLKQQQSATRPTPDNEQMPVDTTQDRLLATGQENSENECNNSCNATEANVGESCSGNEMDSLLIMQKEQHPEHEEGNVVCQFPHGARRASQGTPSHHVDFPSAPTTADVPMEEQPKDLSRENISEDKNNCYNTSRNAATQVYSGDNIPRNKSDSLFINKRIYHPEPEVGDIPYGVPQDSTRASQGTSTCLQESLGECFSEKDPREVPGLQSRQEQLISDPVLLGKNHEANLPCESHQKRFCRDAKLYKCEECSRMFKHARSLSSHQRTHLNKKSELLCVTCQKMFKRVSDRRTHEIIHMPEKPFKCSTCEKSFSHKTNLKSHEMIHTGEMPYVCSLCSRRFRQSSTYHRHLRNYHRSD", "length": 506 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q3ZCQ0-1", "protein_name": "Required for drug-induced death protein 1", "gene_name": "", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTVGARLRSKASSLVGRGPLGRLRRAGDEETDAIVEHLEGEDEDPESQDCEREEDGRRAGTPSARRVHLAALPERYDSLEEPAPGDKPKKRYRRKLKKYGKNVGKAISKGCRYIVIGLQGFAAAYSAPFGVATSVVSFVR", "length": 140 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q4JEI3-1", "protein_name": "Defensin alpha 3", "gene_name": "Defa3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGTLTLLTTLLLLALHTQAESPQGCTEDQKLLIMEDQDISISFTGDKGTALQDADVKSGVICNCRPRGCSFKERVYGECGYNGHILRLCCQPLNTMNKKSPSVI", "length": 104 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q4JEI6-1", "protein_name": "Defensin alpha 8", "gene_name": "Defa8", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKTLVLLSALVLLAFQVQADHIQEAEEETKTEEQPADEDQDMSVSFEGPEASALQNLEIGWPLKQCHCRKFCRPYEKAEGSCRPGLFIKRKICCIQQWTPGRT", "length": 103 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q4KL71-1", "protein_name": "Small proline-rich protein 2A3", "gene_name": "Sprr2a3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSYYQQQCNQPCRPPPVCPPPKCPEPCPPQVWPGPCRPVMCFEPCLPSVWPGPCRPVVCYEQCPPQPWQSTCPPVQFPPCQQK", "length": 83 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q504N7-1", "protein_name": "Pyrin and HIN domain-containing protein 1-like", "gene_name": "Ifi214", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVNEYKRIVLLTGLMGINDHDFRMVKSLLSKELKLNKMQDEYDRVKIADLMEDKFPKDAGVVQLIKLYKQIPGLGDIANKLKNEKAKAKRKGKGKRKTAAKRQRQEEPSTSQPMSTTNEDAEPESGRSTPDTQVAQLSLPTASRRNQAIQISPTIASSSGQTSSRSSETLQSIIQSPETPTRSSSRILDPPVSLGTAYSSAQALGVLLATPAKRQRLKNVPKEPSEENGYQQGSKKVMVLKVTEPFAYDMKGEKMFHATVATETEFFRVKVFDIVLKEKFIPNKVLTISNYVGCNGFINIYSASSVSEVNDGEPMNIPLSLRKSANRTPKINYLCSKRRGIFVNGVFTVCKKEERGYYICYEIGDDTGMMEVEVYGRLTNIACNPGDKLRLML", "length": 393 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q54B59-1", "protein_name": "O-methyltransferase 12", "gene_name": "omt12", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSDWDKTMDLLFGFVTGHIHSRMFETILKFSICDLLEDGPKHYSEISKIIGFKNESYCYRLMRYFVPYKLFNESVVQVGLFSKTPSSTQFSKNGTLKNLGRFHCQDHHYRIFESLPKTLEMGKNQGPSSIGLSSFWEHFETDESYKQLFHNAMKDYTSLIIDRLISKISLSPNFKTVVDIGGSHGFLIGKLLESNPNIHGINFDLENIINSSTSKNENFQHPRLKHVSGDFFNSVPEADCYILKYILHDWSDEKCITILNNIHKSLKPNGKLFINDLVLDPSNYTKEAVFKDILMMQYFDAKERSINEWHQLFEKCGFKIDSVDTSISPQLMIVSKINSSNINLNDCTNFNSEIVEEKLKNSLPQFVNC", "length": 369 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54B60-1", "protein_name": "Probable inactive O-methyltransferase 11", "gene_name": "omt11", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MECSESLELVDKFACGHILSRMFNVVMKHSICDLLEDGPKHYSEISKIIGFKDDSYCYRLMRYFVPRKLFKESVVQVGVFSKTPFSTEFSNNGTLKKLAKFHCNSFHYKLSQVLPETLEIGENQGPSSIGLSDYWEQIEKNEIYKNEFNDGMIGYTTHILKFLKGKIDLSKFETVVDIGGSHGYLIGSLLDRYPNVNGINFDTDMVINSSNEKYQHPRLKHVAGDFFKSVPEADCYLMKLILRCFSDEKCCELLKIISKSMKSNAKIIILDIILDSSKYLNFDTYLDILMMETLDGKQRSLSEWIKLFEMSGFKIDKYESGSPNYLIISKE", "length": 331 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54B86-1", "protein_name": "Hly-III related family protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MPRLDHKKNKEEKDNEPLMMVNNYNIGIQTDNNQEDIQNDYHHFNDLSINIKNNKNNNNNNNKCNSLHHKHYHNRFIINGGNNNNDNNNNNNGDDCCANIELFVDLMLSENEYILSGFRLHTKNSYMECTKSIFKLHNDTLNIWSHLLGALFYLVLFFTSIIKIIKLNNNDGGGGGGIGNNFILNSDEIKLLETIDLPSNFNYLFFQLSCFICFLSSTIYHTYRSHSIVVFKTTLMLDVASIALLILSSVCLIIDSELSCWPYFKRIYLFSFLILILISFLSLPKIMREKRYGLRTFLFAILALQGLVGHLFKIYLQGYFDKDPNQFYNLIGAYTLFGLALSIRRFKVPESFKPGHFDVWVNITFNIVYNII", "length": 372 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54BG8-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIKIMTWNCQGCSTIKSMNQTKNTINLIKPDISILTETNLKKDQNLAQIKNHYSTGGKGKEARGKGVMAINHLEQIEIKNLEEKEGRILKFTAILNNMEINIICIYAPASYDRRKGWFSNNISLEDLEQADIVTGDFNINKYAKIKFKDGSSDKRKFTENETIEFLMMEVGLTEILPNSTTKTTFKDKLIDRTFLSTKMHQLNHSYKIIDKINKSDHNIVVMDFKIPNFTKIYKSPLWKMNSIIIKEDKTIKKIEKIIDHYQETKRKNINITEYWIKFKKKIKKQCITTEKKRILERKKTLSNLANEHTKTKNKYEKETISNEITILQEEERIDRMIKSSINYINNKEIASNLLTSILKKRDSSSQIHRIKNPSNGKIETEQKEITDCFRKYYETLFKEKECDQETHTELLSTWNPPIDKKKLTEMEDRIEEYEVKLAIEKIAEGKSPGEDGITSSFYKIHQHKLIPILTELFNFFLNNEIPTEFKNGILTSIYKGKGDVLEISNRRPITLLNVDYKIYSKIINNRILKILPNIISKYQNGFIPGRLLHNNIIALDLAMEKSDRNTIITFYDFEKAFDSISHKALIRTLNHLKFPRKITNTILSMLTNTNIRVMVNGQLSESFRAGRGTKQGDPISPTLFAIVCECLSTSIRKDNTIIGIKLNQNNSMKIGQYADDTVTLASNIDDADKMDMKVIKFCQATAAKINDNKCVCITKNPKIKTKYKTIGAKEEERYLGFFFNRKGVISKVDDTVNKLENLTKCYSSVSSTLKGRITILKSYLLSQLTFQLYINEINDIKKLENVNANMLFKGDRWAISKERSRRDYEIGGLELWNMATRSNAQKAWIYEQYLREKDDQNCPPHMEVWKSEKENSLSRIHIKCWKAWKLLHHPRERITLKLNQVKPKYENKQKLKVIYRNMMDIKYKGWNKHQPTTGQKLIQKNINHPILPFREARSITTIKGRDLAWRYLLKALPKHHGENCHSCKEEESSMHIFFECKSIKQNIDSIYQKVCKDSNNTYHGPWSEKVLGKLLTPFSSNLIGAIMESIWYRRNQIKFNDNTTIITENQIIHKIKKARDAEWDRTRKIVEKQLRQELRCTDNRESINRTASIKRRLEKFSHNWNSKLMTINIPEHFIPYCSYNTNYS", "length": 1144 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54C66-1", "protein_name": "RING-type domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MYKTKKYKNPFPTNSYKEPENDSDNEYILHNEEDNEDYGSNNNNINNDGFSYEDNIENSDTEDEREDYGYINYNTNNEEDDEPIDLSTPIKKKKANNKSFKPPYKNTTTTTTTTTTTPPTPPPSKSNNNNNNNNNNNNNNNNNKNKENINKESEYELNKFLDLYNDFKSESDNKVKPTATTTTTTTTTTSTSTSKLNKDKKGVIVIESDEEKEDNTIKINKRNGKRKEGEQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQGNEDNLKSENFNKFKKLKSFSNQPTPLPPMLSNPFLNNSGNSHNNNNNRILFNSQFTNASNLNNNINNNINNNINNNINNNINNNINNRNNNTNNYTNNNNNNNNNNNNTNNNNSNNNINNNNYNNNNNNSFSFLPIRSNTLPTIVTRRTGIQSSSSDNGNSNSNHSSSMNKRNTSKSNNKKSTTTTKTVLPPPLSSRTQEEEDYALALSISEGLNGGSGGGSGSGSGSSDNSTKTKRSKSENDLPNEETRHQVEMDRRFAEQLHREQHENINQIQQLQRRLHLNQQRTNNINRNHHGDEDEEDIEMLNLRAYQQIQQQFNQHFNQQLNQLANHPLANLFSHASRGRGRGARRIPHHPHHHHHPHQAQYLTGLSQEQLNLMTRDFSSNDYELLLQLDENINNKGATTSDIENLPVHTLNKPTATTTSTTTTTNSSTSDDNKKNEPTTDVTCCICLCEMEPGDAVRTLPCKHFFHVSCIDQWLKVNKVCPIDKKAIDEK", "length": 766 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54CY8-1", "protein_name": "Obg-like ATPase homolog", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIKGIKLFNNFTNTKQILFFRSFSTAAKGDRLKASHYVKTRGSCKSISIVGLPNIGKSTFFNALTSSNAAMAANFPFCTIDPNIGKVFVPDERLDYISDLLKTKSKIGVQLEFVDVAGLIKGAADGEGLGNKFLGNIRQTSLICHLVRCFEDKGITHVSDEIDPIRDIETIETELILADLQSLEKMLTEGKKKQSNPELQMKFDLVKRISEYLHKGLPARDVEITDMEWPVFHSLHLLTSKPTIYTCNVAEGDAATGNKYTDLVKEYSKSKGLEIEPVVISAKIESELANMEGNDETKKEFLQLYGLENNGLSKVINGAYKLLGLQSYYTASSNECHAWTFKAGWTAPKAAGVIHSDFEKGFIKCDTISYNDFIECKGDEKIAKEKGKQRSEGKAYIVNDGDILFFKFN", "length": 409 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54D44-1", "protein_name": "Probable polyketide synthase 42", "gene_name": "pks42", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIESQREFNCIGGDNQNGVAVIGVGFKIPLDLENCLSSPSELYSALFNEFDSVTKNTSSRWSDNYFKNGDIVSLSAGLLPLREIKSFDPTFFGINPSDADLIDPQQRLLLKCVWNALEDGGIDPISIRSSDTSVYIGCSTIDYFLLNRNPVDPHNHGIQTASYSIPNRISYCFDFRGESLFVDTACSSSLNAVHLGYNSIINLKSKLSIVGGSNLILDPQNSIFFSKQQVNGPSGKCNSFSEEADGFVRSETVGVVVLKNLKDAIKDGDRIYCVIQGSNSNVDGNYEKLNYISPSKLSQAENITKALKSTNGAVNASDIDYFECHGTGTPTGDPIELEGISIALNRTQQSTTLSNPLLIGSIKSNIGHGEASSGIASLIKCCVMFKYRQFLPNINFKTPNPLIKFKEWNLKVVTEPVPFNNNKQTIMAINNFGVSGSNCCIILSEYKSNNNNNNDFKATTHLKSKKFIIPFSSNSSTSLDNYKSLLSNETNNFQDFVIKQINNKSTSLIQRSVIIASNWSEFNESSNEIQSNIKKSIISNITIKKKNAVTVFVFCGQGSQYNKMALSLYENEHIFKSTMDKLDKELSKHYGYSILEKLRSITDEDLVTIHQPILAIPVNVMVQVSLYELYKHWGIKSDIMVGHSFGEIACSYCSGMVDFKTLCYLTYHRSVAQNKTIGSGKMLSINIGAKEYLDSYSTKYPSVEIACYNSETSIVIAGNEELLNEISKDLKSKDIFTAMLPSLSAFHTTHQSVIKDDICSLNFKSTLSKITVFSTVTSNQFGINNNNNNNNNQLNSNYLFQNVIQPVKFSETISNIYKYIESNDMGNEITFIEIAPHPTLQYYLNQMKSQQSEYFNNGEKISIYSACNKKKNDYNEFLKTISTLFVNGYNNINFKSQIINNNNNDNNNNFNLPLYQWDDNEYYKIHPTWKKANKNGPSINHLGNLNDSSIKSFKTYINTRKPQFQWLKGHSLKGKVVFPGMGYISNLLSVYNMNQDITINEIQFKSAFILVDGVNNCLETSIVPLTKNEFNIKFHFKDLKTNKWVLCANANYSLFKHNDNNDKLDIEKLKSNCNYTIISKDELYNNIRAKSGLIYKGLFQGVKEAFIGNRCSLTVLSLNEIENQQEFKHLLENRNFNSLFNTAILDSCLHGSLHSKEQSQIYFDKCEGFKYYSNNINLATSKRNEYKEINVYIETNPVINSTVIVSLKIMLPDGTLLIEIQKVVCKSSIPIIDSTSVIQPSPKDLHTPYYQPKNSLIKPPQSFKHLHCMKEFASIESDNREMVYMSIYHLIFKAINARSPTKINLESLENLTLDQFKELIKDSAANIQRSNQFIYECLKLYHTNHSNYKKNQIKDFIKECEDFNGYNQIIFKTIKIYAKSLFPLPDDDPFTDTIQSLFEDDQLENVYIHLKHLYPVNNLLSEIVFQSIKPIINQTSTFRILEIGAGYGTISQLIFDKLEQLLADNFTSSRIDIEYTFTDISNTFLPRAKERYSKYKRFNIIYKLLDLELPLTEGIQDFRPLYYDIVVMSNVLHVVKDINFSTNEIYKVLKQNGQLIFVEPTYKNLYLDTIFGIFPQWWSFNDDIRTDRCCLEPSKWFEFLETINFKDTIILGQDNKEILKNVENSIILVQTRKPSQLELSINNSPSTNQFKSFENIILYTDDNQQPNDCSEIIDLLKSLELPIKIINNIDQFNQIIKTQYNNNNNNNNNNNNNNNNNNNNTNNNLIIFLKSVNQLNTNNYKDITFEYVQINQILVKLELEENYKLLLITNNSQSSNYLSNSLIGTSRYLFADIVSSKLDIITIDFDTVSIKNHQNVISVINHLLDSKDNSEREYYIINNEINIERYKNESNIKHQLKSKTFQENKDELMVQLDSNLEYRLKSKSKQELKSTHVEIQVKAIGINYKDYATYSGLIDSIIEIDKDKEKDENYDQNYPSIGNDFSGVITRIGSDVRKFKVGDEVCGLAPKTSASHIITEEGYLCKKPSNISHSEAASSVTVYTTSFQSIYSIGDLKKNETILIHSGSGGIGLSALEILKWKNHQGYIFATVGSEDKVKYLTDTYGSFITGIYSSRDKDYQDQIKEKLKSLGCDIDHQGVDLILNTLSVEYMDSNFKCLNQKGRCIDLSITHLTPFDYMDYNKFKFNVSYGNIELVVLPSKIIKDHLKKMLKAFSLGSLRFIPIVEFSNLNIRNAVEYINQRKHIGKIVVKNDVDFINKLFIEQQQQQNSVENNEILMKDKYDISNLELGKNILLTGQTGIILTILKWLYKHSNNSIENIIIISKSKLKWELELFINESTNNRIKIHYKQADVGNNNELNQCFEELRLRHSIEDINSIFHFAFINDIGQFEDVNMNRMDIAHHAKAIGSLNLHNQSIERKWNIKQFVLASSALSVFGGDNQCCYISACSVLDSLSKYRKSIGLPSLSINFGGVTSTGFVSRSGAVEANLESSIINLITPQSLISSLDLFIQNSQTFSNYTHFNFIYDNIESYSLNRMLFKFDYLINQHSSLVSNKRLGGINENNNIGDLLVSKIGELLSIEPSKLNLDFRLVDYGLDSLVIVQLKNFIDKQFQPHLISILQLQNNKISTTIEIIIKGYNNNQNKKIKNEQSNDIPSVVQKETIKDNNENKDDIKIDMDDKKENLKGKKENIDDKKENNN", "length": 2655 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54E06-1", "protein_name": "Transmembrane protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTIINNDNISLATSAKLSQFIVSGDYKGPFTIIGLKTKILSFSLVIEFILLKIELIKERKDGLKINFDDSISGSCNYELNYTKQDTLFQRFQSKFKIEHTINPENGETINTGITLKKLFIISIPMSILFVALNWIWMLAISMTEVSISTALYLKILKTISVIIFMGGIVGIAITTVGTSKGEYPHAIKGEILMIISAAMWGLYEVLTSKFIGDANRTIVHTYMGLIAFVNLILGIPVIVILNVTNFEPFSVPSISVFGMLLLNAFVGFSVNYLINWGLSVTSPLFVRSGELMVIVATLLFDIIIKHMKLPLLALPGYSLIVIGFILSVYIESRDIKQQQEKEKEKQKNNNGETESLLNY", "length": 359 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54EC9-1", "protein_name": "DUF781 family protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MLNKIILIFFLINNIFSIVVSSTKLNPWVFEERIKLYDILINSTKVEIFGDDNLNNCFQGFKIQLEWQKTTGRSMIIDNSNISVNSWWGSMNYYESIIPFISAMNLGIIQPPIELVNIGDDRFCTDYSECDKELMEPWDLYFQFLIKIKDEKYSYSIQQQILKYNWDGHMKSLSIGLKLFNDKLNYLSKNEIKFSTGFVHFVDIISLINFNTNYSQILPIFDSLPPRMLTNSDHPPFFKGFTRTQNFYTVSVLSINELHENQILWNYFLNLLKTKTENEKCRDFINQEIINFTKYPESTLVKLLLKLLLNNC", "length": 312 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54ED6-1", "protein_name": "Probable polyketide synthase 41", "gene_name": "pks41", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDSKNLVDENCNKVAIIGIGFRFPNLKGDITPNELWSKLLNRYDGIVKNDRWNESFFKSGDISTNYAGFIPFEELKSFDPLFFGINPSEGIHMCPQQRLLLKCTWEALEDSGIDPIEIRGSNTSVFIGCSGADYQNLNKNDNKVQQEIFSSSTHSISNRVSYCFDLHGESMTIDTACSSSSNAIRRGYKSIIDGSSNISVVGGINILLDPNISKSYSRLNILSKDGKCKSFDAGADGYVRSDAAGIAILKNLNDAIKDDNNIYCVIDGSASNVDGNGFSDKSNFYSPSKSSQVECIRLALESTNGQVNENDIVYFEAHGTGTPTGDPIELESVSIALKTSENRSSDNPLLIGSFKPNIGHTESASGISSLIKCCLILKNQCFVPNLNFNKPNPLIKFDQWNLKVVTDPIDFSTLNYINKRVSIAINNFGVTGSNCCLIVSSFKGNQIRNNINNKSKSPKQYLIPFSTNSIKSLDLYKSRIDNNVEFKEFAENQIKSKSKKLIQRSVVIASNWDEFNLKSNTINTSNDKLTSNMLVSSNKKNVTMVFVFCGQGAQYSTMAKNLYDNEPIFKKSMDKIDSKLNEYYGFSILEKLRSFNENDLKGIQYSIIAQPSTCMVQISLFELYCHWGIKPSIIVGHSLGEISSSYCSGMIDLDTFCYLIYHRSMVQSKTNGLGRMLSISIGENEYNSKYSSRYPELEIACYNSPSSIVIAGKELILNEIIKELKKDGVFCAILGSPTSFHTSSQLSVKDEILKISFKSKQPTIPIFSTVTTNLYDEMNPFDTKYVYDNIINPVRFTNTISNIYKHIELNYSVNNNSNEVIFIEIAPHPTLSFYLKQMVPEDKKQSVSIFSPLSKKKSNDLFEIQKLISELYCLGYNGIGFNIQLSDHNNTNNQTRVNLPLYQWEDQEYWKLDNLHQYHLSNGPSINHLGISNSNHTPIKSYQTHINIQKKPFQWLKGHQIKGKYYFPGCGYIDNILKIFGESKTDTNPNKELPDILISFIEFKTPLIFMDGISQCLQTNIHSTGKKEYKALFHFKDEKSSSDWVQTSTANFQLFSRGPNLNEDDEQSLFMYNINDLISNQCNLTKLSKQELYSHIKTKCGLNYSGDFQRVDKCYLGYNCSLSEISIIQGVNENRSTFFDSSIIDCCLHGSIGLIDENCQLVFEKLEELTYYSSKVPKTTSQHSKIYVYSKLKPRIGDSYSASIIVMLENGTVLFEMENASFKSTTKIKDPLAMEYPTNEIYSCNLQSKDSLIPSLSSFDHIFKRKIPNEYVDQINIYESFIPKLLFSNINKRCPEITIDEIQSSEIEQLLLKYYKIKEDNDNKWLSRLFTFAFESIKQWYHNEDYDFENVLSPHNFKIFSKSTKIISKLLFPLENDNDEDSPQSLFEGGLLDKFYSSGFSAQNELVGEIIQESIKPILNEKLVFRILEFGGGVGSLSLLVLEKINSLLIQYPNYQIDIEYTWSDISPSFITEAKAKFEKFNDRFNIIYKALNLEQPLIGEKQGLKPQYFDYIIMFNVLHVIKDVKYGVEQIYQLLVPNGHLLFIEPIYKSIIGDGIFGVFDQWWSFQDTEIRKDRCCMKQKTWYKLLKSVNFNDDIRMTPELTCFVIQAQKPSISNLSFSKSETTNYDSIIVFGNKYASNLSNHFIKSIDNGNLQFISTIEELNKIGKYISNESIIYFIKSIDELSVDNFVNITHEYTQINQKLMELNCKCKHVLITNDSTTTNYLSSSLIGAARYYHECPLELFILNFDTPSIIENQNLFKTIEPLINSSINIQREFIINNHKVYYERIKNETKLKSIFKNSSSFESLEQVDNFMISLTPNLEYKVKVKPTSILKENEVEIKVMSTGLNYKDYLIYAGLVESVEPIFGIEFSGIITRISTGSKEFKVGDHVYGIGKSTTSSHIITDIDVISHKPSNISHSEASSIPVVYLTSYHSLYNIGALKNNETILIHSATGGVGLSTLEILKWKGHSGLIFVTVGSNEKEEYLRENYGDMISGIYSTRNKNFVKQIKSKISKLNPFGKSGVDFILNTLSSSDYMDSNFKCLNMSGRIVDLSITHLNSNEFTDNKKFKYNYGYHNIELQYVDKKIIKSTLSIISNAVSSNDLQLIPITHYSIEKVKESIEFINERVHMGKIIINHENQDSIINELIEKQKSINKFDQSIFKQNYKLEPSLLGRNILLTGQSGIVLEILKWILRNSENNSIGNIIILSKSSIKWEMEYLINKVKLINKLGNFFNNIKFHFKSVDISDSGLIDESINKLLIENPDINNIDSIFHFAYTQATCNSDEVDLHHLTQSHSAKSMGAINLHNQSIKRNWKLKNFIMSSSVSSKTSTANQCGYISSNNVLDALSKYRISIGLPTICTNYGLIESTGFVSRNESVAALLSGEGFIPISANLILGTLDLQLQNQAQSSNLILSNFNFTSLNGLPQKSLISKFDYQININEENEKSKSLLKDDNVELTVDQLITFKISEILSTDILKLNKDIILVDYGIDSLVIIQLKNWVDKEFSIPNELTIQKIQNSTINSFIQLVKNSMDKNKK", "length": 2542 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54ED7-1", "protein_name": "Probable polyketide synthase 40", "gene_name": "pks40", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDYKNKYQSNENCNKVAIIGIGFRFPNLKGDLTPNGLWSQLLNKYDGIVKNDRWNESFYKTGDIPTKYAGLIPFEELKSFDPLFFGINPSEVIHMCPQQRILLKCTWEALEDSGIDPIEIRDSNTSVFLGCSNFDYQNLNKNNNKIQQNIFASSSHSVSNRISYCFDLHGESMTIDTACSSSSNAIRRGYKSIIDGSSNISVVGGINILLDPNTSKSYSQLNMLGKDGKCKTFDADADGYVRSESAGIAILKNLNDAIKDGNNIYCVIDGSASNVDGNGFSDKSNFYSPSKSSQVECIRLALESTNGGVNENDIVYFEAHGTGTPTGDPIELESVSIALKTSENRSSNNPLLIGSFKPNIGHSECASGISSLIKCCLILKNQCFVPNINYNKPNPNIKFNQWNLKVVTDPIDFSTLKLSNKPISIAINNFGVTGSNCCLIVSSFKGNQTNNNNNKSKSPKQYLIPFSTNSIKSLDLYKSRIDNNVEFKEFAENQIKSKSKKLIQRSVAIASNWDEFNLKSNTINTSNDKLTSNMLVSSNKKNATMVFVFCGQGAQYSTMAKNLYDNEPIFKKSMDKIDSKLSEYYGFSILEKLRSFNENDLKGIQYSIIAQPSTCMVQISLFELYCHWGIKPSIIVGHSLGEISSSYCSGMIDLDTFCYLIYHRSMVQSKTNGLGRMLSISIGENEYNSKYSSRYPELEIACYNSPSSIVIAGKELILNEIIKELKQDGVFCTILGSPTSFHTSSQIPVKDEILKISFKSKQSTYPIFSTVTTNLYDEMNPFDTKYVYDNIINPVRFTNTISNIYKHIELNYSVNNNSNEIIFIEIAPHPTLSFYLKQMVPEDKKQSVSIFSPLSKKKSNDLFEIQKLISELYCLGYNGIGFNIQLSNLNENDNIQTSLSLPLYQWEEQEYWKLDSLYQHHLSNGPSINHLGISNSNHTPYIKSYQTHIDIQKKPFQWLKGHQIKGKYYFPGCGYIDNILKIFGDNSESTTNPNKELPDILISFIEFKTPLIFMDGVNQCLQTNIHSTGKKEYKALFHFKDEKSSSDWVQTSTANFQLFSRGQGLNEDDEESLFKYNINDLISNQCNLTKLSKQELYSHIKTKCGLNYSGDFQRVEKCYFGNNCSLSELSLSQGVNENRSTFFDSSIIDCCLHGSIGLIDENCQLVFEKLEGLTYYSSKVPTTTSQHSKIYVYSKLKPRIGDSYSASIIVMLENGTVLFEMENASFKSTTKIKDSLAMEYPTNEIYSCYLQSKDSLIPSLSSFDHIFKRKITDEYVDQIKIYESFIPKLLFSNINKRCPEITIAEIQSSEIEQLLLKYYKIKEDNDNKWLSRLFTFAFESIKQWYHNEDYDFENVLSPHNFKIFSKSTKIISKLLFPLENDNDEDSPQSLFEGGLLDKFYSSGFSAQNELVGEIIQESIKPILNEKLVFRILEFGGGVGSLSLLVLEKINSLLIQYPNYQIDIEYTWSDISPSFITEAKAKFEKFNDRVNIIYKALNLEQPLIGEKQGLKPQYFDYIIMFNVLHVIKDVKYGVEQIYQLLVPNGHLLFIEPIYKSIVGDGIFGVFDQWWSFQDTEIRKDRCCMNQQTWYKLLKSVNFNDDIKMTPELTCFVIQAQKPSISNLSFSKSETTNYNNIIVFGNKDDSNLSNNFIKSIDNGNLQFISTIEEFNKMTKYISNESIIYFIKSIDELSVDNFVNITHEYTQINQKLMELNSKCKHVLITNDSTTTNYLSSSLIGAARYYHECPLELFILNFDTPSIIENQNLFKTIEPLINSSINIQREFIINNHKVYYERIKNETKLKSIFKNSSSFESLEQVDNFMISLTPNLEYKVKVKPTSILKENEVEIKVMSTGLNYKDYLIYAGLVESVEPIFGIEFSGIITNIGSGNKEFKVGDSVYGTGKSTTSSHIITDIDVISHKPSNISHSEASSIPVVYLTSYHSLYNIGALKNNETILIHSATGGVGLSTLEILKWKGHSGLIFVTVGSNEKEEYLRENYGDMISGIYSTRNKNFVKQIKSKISKLNPFGKSGVDFILNTLSSSDYMDSNFKCLNMSGRIVDLSITHLNSNEFTDNKKFKYNYGYHNIELQYVDKKIIKSTLSIISNAVSSNDLQLIPITEYSIENVKDSIEFINERVHMGKIVVDHENQDSIINELIEKQKSIDKFDQSIFKQNYKLEPSLLGKNILITGQSGIVLEILKWILRNSENNSIDNIIILSKSSIKWEMELLINKTKLLNSNSINSMGNYLNKIKFHFKSVDISDSGLTDKGIHELLIENPDINNIDSIFHFAYTQATCNSDEVDLHHLTQSHSAKSMGAINLHNQSIKRNWKIINFIMSSSITSKTSSANQCGYISSNNVLDALSKYRISIGLPTICTNYGLIQSTGFVSRNESVAALLSGEGLLPISTNLILGTLDLQLQNQAQSSNLILSNFNFTSLNGLPQKSLISKFDYQININEENEKSKSLLKDDNVELTVDQLITFKISELLSTDILKLNKDIILVDYGVDSLVIIQLKNWVDKEFSIPNALTIQQVQNSTINSFIQLVKNSIDKKNKK", "length": 2552 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54EN3-1", "protein_name": "Alkyl transferase", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSNCSNNSENCNINDNKKKEENVKNQNSNKNSNNNNNKSNIESIILNKKSKFSSEKELDEKENKDLKDLSNNKPINIDEYEGLPRFENEQNARSKSSLWSKLCDWMYDQNFKIASSTLKNGPIPKHIGVIMDGNRRFAERNHLETKEGHKKGFNTMLDLCQWGLTLGVKIISVYAFSIENFKRSKSEVQDLMELANNKFTEMISKSHKLQQLGVRIRVVGDHSHIPEKTKSILAKAVKSTENNTKALLNICLSYTSHEEILHSMKILSKGVNQEKKIEIEDIDQDLFENCLYIKEDLDILIRTSGEYRLSDFMLWQSCFTNLALVNTLWPDFSFFHFIYIIFLYQFNSKTLKNEIQNQYKFNNNNNNNTDNNNNLKENIKNLKSDQRVKEFINHLKISEEKLFDEFISKYNEEEEEEEEI", "length": 420 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54F52-1", "protein_name": "Saposin B domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKLIFIVCLLLIFNYFIGISFGNKQINSNQQQQIINTDKNYNHNKNNKIIVSHNKNNNNNNNYNEIETENLGCTFCKYLTEKVEEYLQANSTEKEIISYLDEECELLNSPNLVLTCQNLVQQYTPIVIELIDNNESPSVICENVNICPTSSSSSSSSSIEEEIIKKLNIDDNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNEEEEVNTCEICNLVSNLIEKYIKINNEVDEIRELIENECELLSNSKVSSCYSLVDQYFEHFYVTIENNYSANEICQLFQFCPIESSSSSSSSDIINNIPLQDSGCTVCTVLANYAYKVQANESIPEIIGSMDEICNKIGAWRDICNSIMRSGGQQLVEDIVNKGEGVYTACSNIGYCQSSSSATGTSGFSSGGSGTSTGGGYSTGDFYYKPLK", "length": 416 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54GT5-1", "protein_name": "Endoplasmic reticulum junction formation protein lunapark", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGNLFSKKNGFEKQLLDMETKILNLEDKLSNSRIFHQKVLHKIVLYSFAIEFFIILFTYVKSRSLESIPEKLFCCIYLVLFPIFILILTKVYGFVYKYLIKKNEVRLDSLKTGLQKKLDERKRETDYENTQKLLDRYEKNPPSPTNKPLGPPNLNNNNNNNNNNNNNNNNNNNNNNNNTLGNSMRNRNQPFNISSQQNQQQQRMIQPQQLSPQQLQLLQQQQRLSQQIVPSQQQQSQSQPQQQQPILNQPYNINNNNNNNKPPPPIQLPPQQSSQYIGNQQRLPPQQYQNEQKSKWWLDKLVDYLISDGPTHGSPLICSNCHSHNGYVPVEELSNIQFRCRVCKTFNQRDSVNNSTTNDDRNNSQNTGSNQQQSQSLQDQQPSIEEIDKNFSVTEQKNETNNENYSDSEKQLEENNNNNNIDNDSGSSSSQNTPNKKKGKGKGKGTPTKKTN", "length": 452 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54H60-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MLDFFHLKDVDEFFRLLEKKNLQNLDNQIDGPGNLNWRTTYTEKDFSKVPKFRGIIHIVQIRDLGTKIHRDLLYEIMFEKLLDIARLNNESKLLKNEIQDLKTKLDEYHNNNSTTNTDLIINSFINVIDTTTTTTTTKTTMGATSIDKKQSEGDSIDKSIELDFFKIKSDQSQQSSPSHKLEEKQNQVNNITNEIPQESIKTVKQQTQTETNQQTFSSTSPSHQNEEKQDKQEEVKQEEVKQKEGIQKEDKKEEDKKEEGKQKYGEIFIIEIPQEEEKQKEEGKQQDGENFIIEIPQEEDKQKEDKKEEDKKEDKQEEDKQKEEKLEDKQKNGEEFIIEIPQNETLEIKVDTHPRSSNDDVSTAEMEVEALKTPLFAETTFVTKQQVITNKKLLVYKQSDFFPNMTTLLQSRLKDVTVQEVKDLTKIGLNDNSYSVGDFENVFVLYAVSCMGARTDSERDAFKIKSIRSIIGDKVPIIYGVFMIGKNGPTRIKVEHTQTSISITHSMSDIGRNLQNNENLKQLQSFLQQ", "length": 529 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54H72-1", "protein_name": "Tudor domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSNIDFEDYEFYDDSDFEINTVDESVMTYSSVFDFLRFGKIPKFDTQTKMKHFKDNISKYRIESKDILHTNVDSKILRRLSEIPRVEKIFPDPNTLQLEVFKPNHELRNSNGELLSKHRPLQETLKLIEKQYYWECKFIHTSMEVDITKLYSFCDLCSQSSVSRDMDIDSNDEDKILEQMDIVEKSFSNDRNNNNNNDDNNKSIDEKDKMNICGIGIDLEAIKEGKLFEDELAEALGFPEYNSSVDNSFNSSVNNSNLNNSSLNNSLNNSKNNNNNDDDNNNNNNNNNDDNNNNNNNNNNNNNIISNIDNNNNNNNNNNNISNIDNSNNNNNNNNNNNNPVNDDFSFIIPKDYQSKNHLNDNENKDDEKDDDKDDDKDDDKDDKDDDKDDDKDDDKDDSKDNGYIKTNVSLSSSSSSDNERDDGDSHSDKSVDNDENNNNNINNIISDCNNNNNNNNNNNKINGRTFTSRRTRSDSNTSNSSVGSYISNSSKSSANSYDFSSSDQDYKSPNSPTVKKTRGASLVNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNINNSILKPKLKSKRASASTAINSFISQFITPKHPPKSSSRLKRANRSNDSSDSGDSSSNNSSRSSSDSSDNENNNSYYLPIQSRRSTSKQILKDHLKSPTKKPRRIIEEDFYHVEEKKSPTSKISTPISRSASYNFGRSSPGSSPGSSPSLSPYSSPPQSPPHVYNHNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNYNNNNNNNNNIRSILKSPQSPSISPIKTPRRSPQQQQQLQLQLQNYIPMPTKTKTPTKAPYVPNYALAPIEPKPTQKTPVHVFGGNQLSVKKRQTIEDMITEVLKMNVDTAALKLPLPKVGQHVEGKSNMEDYKDAWFKGVVKEVLPNDFFLISYIDGGEEELSYTRLKPNLTSELEPLKLEEIVVGGEYLGSYRNFYYNVYVLEILRHSIRVYFADLEMAKTIKYSQLYLLSSFVKR", "length": 998 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54HE0-1", "protein_name": "Conserved oligomeric Golgi complex subunit 5", "gene_name": "cog5", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNNNNNNNEGVSSSSSSSSSPLPNISSPNLISNSNIENDIEIKKKSNNNNNNIFEGDNSHIYNQFLGEDFNVVHYTSNALKVSSISLSLNTLTSCTRELGQELTENITTNYDDLFKLANNIKELDQLTDTLKLGVSNLEESIQRMKNDISEPYNKVKSHIGQLKRVQDSCELLRKLIRYIQLVKKLKNHLQAGSRDLSKSAQCINEINLLKKDSDLTGINIIDSQVVWIKTCSDQIITISSTLLYQGMENQNQTDVANSLQVFHNMTILNEKVYSIVNLTTEKVIKNIKALLNVNKLIADLPKTTITNNINNNNSNNNITTNNNNNNYNNNNNNNNNNNIISTSTDKSIWLKFESLIDTLYSSLIQILHLQRVLLKIKDPLTHKSLMEVLLIKQHQLQQQQQQQQQQQQQQQQQQQQQQQQQQQVGTTSNNTQPILIEMISTLFWKSILKVLENNLLVAAKSSNIIENTFIREYPKVSKFFLDFIKKLQNYIDIHQMDIQQQFMIVLSNINQIIGNNNSNNSNSNSNNSIESSLSTSSSSSSSSSSSSSTTTTATTSLILLSADDYKLSLFKSIGLFEKAYLEYSQSKMSTIVNGLFPQSTWSSRSTLPVIPNGKQLVDLSKTIWSEIEWLVGNNDRQLLGKLMLVVSKVIDLFSSKIESMVQPPGLIVLNSNIGSSSSTGGVNNNSNSNNNNEIITINENSKPTPSQTVNTLLFNVSIQLNSSIQSLLTSQPLERESIIVIEKSLNSLITICTNIITPLMNSFFTHIEQIFSTIHNEDWYNEKTTKMLINKSNQTCSSYMESFKTLVNYFQNQYLMRFTPCQLLNNQIKSMISKIFIVYLKYCSLLKQPFSENGKLKMVNDLTHLEFAVTPLLVSGGIKEIGESYNLIRNYKQSIFN", "length": 898 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54IX3-1", "protein_name": "Probable polyketide synthase 26", "gene_name": "pks26", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "METNNNKNIQEDIAIIGFRIPGCQDNTPSELWNNLMNKFSGVGKTTERWSDNYHLSGDINNGNSGLLPLKEWKKFDPAFFGINPTMVSTIDPQQRILLKCTWEALEDAGIDPIKLRGSNTSIFIGCSTGDYLDMVKSNNEIQTNLFGSVNHSLSNRISYCFDFHGASMTIDSACSSSLNTVLLGCQSINQGKSNLCIAGGVNFILDTTIPTAFSFLNILSKNGKCMTYDEGADGFVRGEGAGLVVLKSLKDAIKDGNNIYCIIKGGNTNVDGNGNADKANFFQPSKQSQSDNIKLALESIKKKSMLDIDIDYVETHGTGTPTGDPIEVEGISKVFKENHSPENPLLIGSLKSNIGHMEAASGVTSLIKCCLMFKNKSFAPNVNFQKINPKIKLDEWNIKVVTEAIPFKKNKITSMVVNSFGVTGSNCCLVLTESINNNNNSNVDKITKNEKEYLIPFSANSNQSLKNYIEEVSKIDESLQFEDFVYKQLSNKSTSLFQRFVVTSKDWKELKYKLSQPLPLKEISSSISVKKPNPITVFVFCGQGSQFNKMGLELYNNDKNFRNYIDRFDKKLLEYYGYSVISKLRSIDDNDLITIHDPIIAQPATAILQISLFELYKHWGINPSFIVGHSLGELPMAFCSGMIDFDTVCYLLYHRSLAQSKTNGCGKMLSCNISSEEFVKNYSPRYPFLEIACYNSPNSIVVAGKESILLELSKEFKNSGIFCAMLGSLSSFHTSSQLEVKDHIYSLKFESKEPVIPTFSTVTTHLFNSNKLYDNDYIFQNIMKPVLFNETISNLYKHVENNQLGSEMIFIELAPHQTLSFYLKQLIPKDSNYFSNSNSITILSPLHKKKNDYLEIQQTISTCYCKGYDVNFKSQILIESKTNISNKSLPLYQWDDKEFWKDLEKQKRILQGPPMDTLGFSNEKSPILKSFETKIDIKKKPFQYLKGHIVKGKIYFPGVGYIENLLKMYPSQDIDIDSMEFEAPLILIEGIVTCLQSNVYKIGKNEFKVQFHFQDQKTKQWIQSSFANYHLSHRDDFDPTTNKLNIQNLISNNCNLTKLSKNQFYNFIKAKAGLSYNGEFQGVEKCYLGDNCSLVEIPFDTSNQDVETNINMIPILDSCLHGVHILYVEQCQMVLEKIEGLKYYSSTLILSKQKEQQKLYVFTRIENKDLINNSISASIIVMISDGTVFFEIESVSLKSLIPLKDPISIENPTDELFSSYLQSIDSLISEPSSYKSIYKRNEFISSGMSDLSRSDYQQFISTLLYTNLIKRNQSIESDLRNQIEFEEIKAKYCKNSKFERLFTFVIETIKQYDGINGNLNSWNEGNIDIYKILIKSTRIISKLLFPLQGEDTTIDTPQSLFENNLLDDFYNINGNTVIQNQLVGEIITQSIKPLINEKMVFRILEFGGGVGSLSIVTLNKINQLLEQHPNFQIDIEYTWTDISPSFIPDAKKLLSNIKGVTIIYRSLDLEESLIEKQLLKPSYYDFVIMSNVLHVIKEIKFGIDEIYKVLSPNGQLLFIETPYRMLICDSIFGVFDQWWGFTDTGIRVDRCCMKQKTWFKLLSESNYQDIIMSDDIKDCCFVIQAKKPSISSLEYKLKIDSQENDKIIVFGENDTFMKYLENKSTKQIIKIKTCQQFSDLITSNSKEINNQSIIYFIKTLNQLLIENFKEITLEYIQINQLLLSSGLSCKHILLLNQSTSENYLGSSISGAARYFDEFPPLKLYSFDFDKYSLNNESINIIDDIIEPIIKSMNNSNIRKELLVRNNKIFFERYKQEKRIKENYKSTSFENDKSLFVHLNANLEYELKSKQVKLKQNEIEVNVKATGINYKDYLVYTAMTPSELINHKGESNPEFGHDFSGIITRIGDDDGDNDNEFKVGDQVYGIWFNTTASHIIVDKEFLCHKPSKLSHTIASSIPVVYITSLYSLYNIGNIQNDESILIHSASGGIGLSALNILKWKNHKSHIFVTVGSKEKEKYIHDTYGDFITGIYSSRNKDYLKLIKRKLTELGSNKKGVDIILNTLSSSEHMVSNFKCLNHRGRIIDLSITHLNHNEYTCNNNFKYNYGYHNVEVLFVKGDIISKLLKNITSAIENGSLSTGIPIIEFNDSDCFNAIEFINKRQHIGKIVVNHNKENLIQELIKKTNLPIIKSNYQINSDHLGKNILVTGQSGIILEILKWIVKYSTNVENIIILSRSSLKWELELLVNKNKNKLNFIYKSVDVGNSLEIEKVIDEILMENPQINNVDSIFHYAFTQISCKEHEIDQVHLNVSHQAKTMGAINLHNQSIKRNWKLINFIMASSAAGLIGSTDQCSYVCSSNVLDTFSKYRKHVLGLPSICINYGLIESTGFVSRNQSVAVMLDGQGIRPMQTNQILGSLDLFIQNPSKSTNIILTSFNFNEFATGNLQQSNVHKFDFQFNCCLSQKSKLMANNQASENPVKDLLINNICELLSIDESKLNIDIRLIDYGSDSLTIVQIKNLIDKNLLIPNLISIQMLQNNSISDNIKILTDSYNKKKQNEQNELKNIKVGSFTKK", "length": 2531 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54K45-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTKILYLIIYLTLTIVKGAPLYNCKKLNCSSMNTNCKVFGCSPMFGCFETSKCPQSNVDICHTNHCDENTGSCYQIADTCNDGNNNTIDSCGPYGCVNTPVNPPEPTQSCEQKCNDNNPCTVDFCDFRGDCYHYETRCSDYDACTLDTCGEKGCEYRPMNCDDNNPCTADFCSMLYGCYHEPIECSVKVPCRTDSQCNRNNFCETYSCDLSSNICDYYTRDCGGNPCINNECRTGTITN", "length": 239 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54K50-1", "protein_name": "Phospholipase D Y", "gene_name": "pldY", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIINRLFIIIVLFFVNVNSKIISESTLNSCQGGTIQIAESIPLGLDISTNLSTHDAWMDLITNAQESIDLGFFYFTLLGGSDLDPVYGGQLGIDIFNAIVEAHSRGINVRIVQNEPSESFPDTETQTLAKLGIQVRSIDWVSLVGSGVLHTKLIIIDESSAYVGSANADWSSLAQVKELGIVLKNCPTMVADTEIAFQQYWNAADFTSLPINDWGSNYQALFNNTNMASLSLNNNNNNNNKNKNNDNDGSGTNQMYEMFLAVSPPQFQSTYRTGDIDALMDAINNADQSICITVMDYTPTTLYNDPNTYWPLIDNALRAAAFNRNVQVRMLISHWNYTSPIIPQWLHSLNQVDNIQVRWFVVPDFSTNPQIPYTRVNHAKFMVTEKQSYVGTSNWSQDYFTVTGGLSYNVFNNDFTNQLQSIFNRDWNSPYTQPIQNF", "length": 438 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54K65-1", "protein_name": "Band 7 domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNSIKKLSTTAIKFTKQTQRFNKRGFFKILNQYERGVVFNFGKFHTVKEAGFHIVIPFIQKCDIVDIRTFTYTLDKQKIISKDNINLTVDALVVFRIHDPKLAVTKANDCILLVNEMAQIKVCEILSHNTLDQVLHNRDKISNQIHDELKEALNKYGVTIEYLKLKDIHFDETIAKAIAKKVEAANLRDIKN", "length": 192 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54KF5-1", "protein_name": "Protein LEG1 homolog", "gene_name": "leg1", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKSNKTIFLILLFLINFNSIYSFNFKKEIKISNDKINLPTYNPWIFQDRFNLYSILINSTNIPVFGEDNSNNCLHGLQLQFEWQNRSGRLEINQGHVNTKSWWGDMNYYLSIIPYLSAMKMGLVPVVEIVSINDQRFCSTYEDCDQEVLNNWDNFFQQIINIRNNGSEGDDQQLLKFMWTAHIGSIDKATKLFTDSLLLLPKNELRFGNGWAHFVDVIATVNFNTNYSTVYHLGQQLPPIMLNSNDTHPSSIESFTKEQRNVVLTMYEINDLSSNNLVWNSFMYLLKKMTKNEICRNLINNEINIFLNSPVPTIIEILFDILTNNC", "length": 326 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54KK9-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTEVPNQKHNDGGVGVTVGNFVKDNETNVNNNNNINGKGENDNNNNNNNNTIIDEPKLLNNNNNNILVIPLTTNIIDNELNQQKQHTLPLPLPPPPLPTQPQQITPPLPTQTQLPNNMLPSPRPIQQPKIRQQTQQQQAQMQQLQLQIQQEIQLQLQQQQQQQLQLQQKQNESEINGLFSPNFSSSSSSSLSTTPNMHSPLFNNNNNNNTTTTTTTTTTTTNSSTNNTNSSTQTKNASTNKISQDVIGVFDDTDTESEGEEYHSGRSIDFWNKDYKDIAWRCNWIDLQIRDLQYQSMVCDQLYHKVRRSKQKIIPDNKSLSSSIDNNNNNNLKSIPIETIDHSNNAITSSNIPYSNNEEEQQEQQQHPSQSIRTTSVVKLRKPRKLIRRPTVKLSAKQMTTDLEAHPLFTFHKGYFKFENAIKTNIINEMEIKYQEKEKPPKLLTLSEERLKQYINSNEDVDVVNLFATNESKRLSEKRRGRIPSDKKEKVSSHRLKSGDEIDGTSSSTATATTATTTTTTTTTTTTTNKKSRRSRREKKKEKEREKQEKEKHIKTKDEQKDREKKEKAREKELEKERKREKERIKEKERQEKERLKKEKELEKNKKKEKKLLKEKEKEIKEKKVKLKNQENIIEKDLTINNTTTKTTKSKKSSSKVKKSEQEGVKLENVEIEDEEVEEEEEEEEEVEDEEEEEEEEEEEEEEEEEEIEEVEDNEEEKRKEERRRRRRKRRILRRRKKLRRKQRKRQLFLQKQQQQQLLQQQQQQQQQKLLQQLKKRDESNGLSYKEIITPEWRDISSFANNDPSLPSPLLLSNPLLAQDIKNITTTTTTITTSEPISKFSTITEEELLIRQTTNGIDGTPMNGIGEDSESSGSEIELDEDAMKIIHARNEIEEKRRFFNTIKQIQMENPVPSYKRKKESLPVEFVAPTVEELLPSYHFNKKSIKLLGKSWNGDFEYYSSSDEDDYDDSDDYDSDDDNDDEDDDDSDSDDEDESDSDDYDSEYDSDLSDSDDSESESSDNELDGLYSSESEINHNSSGDEDEMDVELNNHHIPSKNSKNSKKQPVNNNVNNSNNLNGSSGGGKINSKPSKQQPRNSKANPPSKQQPTPLKQQPTPLKQQPTPLKQTTTPSKATPSPKQQSQQQQQQQQQQQQQPQQPQQPQQQQQQSPKPTPPLVSTTPPLSSVPLSPPTKTIRSTRGVSSLSNSTSSLPKQTNTPPISILSRKRNQSQSSVTDAPLSPTTTATTTTSPKPTTRRKGKLQETIPVEETKIIEETKPFEETVPIKENSTTTPLKRTRRQTKQQLVNGETTTPLTNGDNHVEKTDSNSTDVKVDPTSWWGDKQYKIQPVMEATVIRFKRVKNDDGDDDDQIQNNQKNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNINNINNTEDLESKIKETKSINIPMEISTNGNDFQMKEKEGE", "length": 1472 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54KU3-1", "protein_name": "Probable polyketide synthase 25", "gene_name": "pks25", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDNSYLNNPQFDINNGNKEVTDDDNNKNNQDNLVAIVGVGFRLPSGENERNNTPQALWNNLINGFDGVVKTSERFNDNFFKNHEIANNYSGLLPLDEVKSFDPLFFGITPNEAQTIDPHQRLLLKCTWEALEDSLIDPISIKGTDTSVFIGSSTNDYLTLNRNEVKSNVFGSMAHSIANRVSYCYDLHGNSITLDTACSSSLNAIALGYDSIKNKKSKMSIVGGVNILLDPYPYKAFSILNMLSKSNGRCKSFDASADGFVRGECIGVVILKNLKDAIKDGNRIYCTINGASANVDGIGYSDKSNFYSPSSISQSENLKNAIQSTNGTVKPSDIDYVEAHGTGTPNGDPVETEGISKVFKDTRSTDTPLLIGSFKSNIGHCEAASGIASLIKCCLMYKNKCFAPNIHFKTPNPAIKFKEWNLKVVTEPIPFNENKNTSMIINNFGVTGSNCCLVLSQFNNTNKQKQQMKTKINNYLIPFSANSVESLKKYQSLIINSKENELKYSFEEFVKNQVFIKPTSLYQRSVIVAKDWNDFNNVENQVKYQTSSSTSSNITITNKNNNPITVFVFCGQGSQYNTMALELYKNEKVFRNSMDMLDNKMKNYFGYSILEKLRAIQDSDKRSVHEQTMAQPSTVIIQVSLYELYKHWGIKASFMLGHSLGEVTTAYCSGMIDIDQLCYLIYHRSTLQIRTNGLGKMLSINISSDEYKTNYMSRYPTIEIACYNSPSSIVIAGNEQILNEISKELKEKEIFSAMLGSLSSFHTSSQNIIKDDILNLNIQSSQPVIPTFSTVTSNLFNESTIFDSEYFFDNISKPVSFTQTISNLYKHIEDNQIGSNIVFIEIAPHPTLSFYLKQMIPKQSQYFRNGESISVYSTLHKKKNDVEEFQKSISQLFCDDAYDINFKCQFNNINSNIEAISNFNLPLYQWDDQHYWLNKSIEHKNNLIGPPISILGNSMQDSNPFIKSYQTIIDTGKDAFKYLKGHNVSDKCYFPGAGYIDNLLKLYPNQDLTINSIEFKTPLILSDDNGQFLQTNVYQTGKSDYRAQFHFKDNRTNVWVQTCTANFQLYNNGKVDKLNLEEIKSTKCNLSSIPWDKFYPHIKNRTGLNYKDKFQNTIECYLGDNCSLTEISLELPENFHDQESFFNTPILDICFHGSIVLIKDNCKLVLDKIDGFKLYTSNIPKNRFDHLSIFVYTTMKSTKSNSYNSTYTVMLEDGTVILEVENLICTSLTPVKDPLLIEIPTDMYYTPYLQSKDSQIQSPLEFKSIYQNNQDNDSLLIPNVVLETIKPLINEQMEFRILEFGGNNLSNSTLLLNSINSLLEENPHYEIDIEYTWSDNNSSILKDAKLELSKVDKGYLSILYRSLGLDVDNSLLEKQKLNPSYYDLIIVSNISNLTKDIKYSLNQIYQILTPNGNLIINEQQPNNENNENNEDSLKNLLVNCNFNSDIMMKSSSVSDSDIKSIIIQAQKPSLKLQPKTINTFDQVILYCNQDEQFQQQQQLINKFESHYNNNCKIIKVSTIEEFYKLSTTITNNSIIYFIKSIEQLTLENFKSITFEYVQINQKLYEFKSKCTHVLITYDSQSSNYLSSSILGAARYFDEIPTLQLFTFDFDKDSLINLDISVIDHLIDPKQNTLIEFFIKKNGKVYFERFKKGLKKNSFKSESYHQITNEQEILISKLDENLDYQLKSKDSILKPYDIEVEIKATGLNYKDYLVYSGLIKLKGDSVDFGLDFSGRVSRVGIKSSKEFKVGDEVYGIGQSTSSSHIIIDSMHACHKPSKITHVQAASIPAVYATSIHSLYNIGNLREGESILIHSGSGGVGLSALEILKSNNHSSPIFVTVGSEEKKQYLINTYGNLITGIYSTRDTNYQKQIKNKLIELGYETHGVDLIINTLSSEFMDSNFKCLNPEGRIVDLTITHLNPNEFIDNNKFKYNFGYHNIELYYCEKPTIKKLLQSISKSIENNTLNYLIPITEFSNSNIKKAIEYINERKHVGKIVISHDTDITNKLIENQPKIDYSLLKSNYKIKNLGKNVLVTGQTGLILDIINWIMKYNSTVENIIILSKSSMKWEMEFLINNNKTKIKFYYKRCDIGGDSDSINKTFDKLFTENPTITNIDSIFHFAVVQITRKVKDIDMKSLNISHDAKTIGAINLHNQSIKRDWKLSNFILASSILSKVGSLDQCGYVSACCVLDSFSKYRLSIGLPALSINIGAMGGSGMVARSELVETVLNGQGYNLTSTNQLLGTIDLLIQNPGQESNNLMVGNFNFPVFNNFKQKIHQKFDFIFNALDSNSENGDGSNIKNSTNIKDKFLNKVSEFLSIDSSKINNDIKLMNYGADSLITVQLKNWVDKEWSPNLITIHQIQSNSIGMVCQIINDNFEKKK", "length": 2380 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54KU5-1", "protein_name": "Probable polyketide synthase 24", "gene_name": "pks24", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKQNKINKAEILQVDDKHVEENLVAIVGVGFRLPSGSIENERNNTPQTLWNNLINGFDGVVKTSERFNDNFFKNHEIANNYSGLLPLDEVKSFDPLFFGINPNEAPTIDPIQRLLLKCTWEALEDSLIDPISIKGTDTSVFIGCTESDYHNINKNEVKSNVFSSLNHAISNRISYCYDLHGNSITLDTACSSSLNAIALGYDSIKNKKSKMSIVGGVNILLDSYFFKAYSSLNILSKSNGRCKSFDASADGYVRSECIGVVVLKNLKDAIKDGNRIYCTINGASANVDGIGYSDKSNFYSPSSISQSENLKNAIQSTNGTVKPSDIDYVEAHGTGTPTGDPIEVEGISKVFKDTRSTDTPLLIGSFKSNIGHCEAASGIASLIKCCLMYKNKCFAPNIHFKTPNPAIKFKEWNLKVVTEPIPFNKFKNTSMVVNNFGATGSNCCLVLSQFNYNTINNNINNHNNNHNHNHNHNNIKINNYLIPFSANSVESLKKYQSLIIENKEYESQYSFEEFVKNQIYNKSTSLYQRSVIVAKDWNDFNNVENQVKYQTSSSTSSNITITNKNNNPITVFVFCGQGSQYNTMALELYKNEKVFRNSMDMLDNKMKNYFGYSILEKLRAIQDSDKCSVHEQTMAQPSTVIIQVSLYELYKHWGIKASFMLGHSLGEVTTAYCSGMIDIDQLCYLIYHRSTLQIRTNGSGKMLSINISSDEYKTNYMSRYPTIEIACYNSPSSIVIAGNEQILNEISKELKEKEIFSAMLGSLSSFHTSSQNIIKDDILNLNIQSSQPVIPTFSTVTSNLFNESTIFDSEYFFDNISKPVSFTQTISNLYKHIEDNQIGSNIVFIEIAPHPTLSFYLKQMIPKQSQYFRNGESISVYSTLHKKKNDVEEFQKSISQLFCDDAYDINFKCQFNNINSNIEAISNFNLPLYQWDDQHYWLNKSIEHKNNLIGPPISILGNSMQDSNPFIKSYQTIIDTGKDAFKYLKGHNVSDKCYFPGTGYIDNIFKLYPNQDLTINSIEFKVPFVLTDGIGQCLQTNVYQTGKSEYRAQFHLKDEMNNQWINTSNSNFHLNSNDNYHEEKQKLDIQDIKQTKCNLSSIPWDEFYSLMKTQLGANFYGIFSKVVECYIGDNCSLTEISLELPENFHDEQSFFNCPLIDACFHGTVILYIQKNCKIVTDKVEGLRYYASNIPKNRDEHSSIFIYSTLKSSPSDDLLSSSIVVMLEDGTVIIEVDNLVVKSLTPVKDPLLIETPSDFIYTPYLQSKDSQIQSPLEFKSIYQNNQVDDGLLIPNVVIETIKPLINRKMEFRILEFGGNNLSKSTLLLNEINSLLEENPHYEIDIEYTWSDNNSSILKDAKLELSKVDKGYLSILYRSLGLDVDNSLLEKQKLNPSYYDLIIVSNISNLTKDIEYSLNQIYQILTPNGYLIINEQQQQQQQQQQQQQQQQQQQQQLLNNENNKESLKNLLVNCNFNSDIMIKSSSISDSDIKSIIIQAQKPSLKLQPKTINTFDQVILYCYQDEQLQQQQLINKFENHYNNCKIIKVSTIEEFYKLSTTITNNSIIYFIKSIEQLTLENFKSVTFEYVQINQKLYELKSKCTHVLITCDSQSSNYLSSSVLGAARYFDEIPTLQLFTLDFDKDSLTNDLDLFKTIDYLINPKNNIQREFYIKNSGTVYFEMYKKELKNLKNSYKSESYHDLSKQQDQLVSKLDEHFEYQLNSKQIDLEPYEIEVKVKATGINYKDYLKYNEMIKVNEAGIGFDFSGVVSRVGIKSSKEFKVGDQVYGIAYETSSSHIIIDSLLACHKPSKITHVQAASIPAVYSTSLYCLYDVGNLRDEESVLIHSGSGGVGLSGLEILKSNNHSSPIFVTVGSEEKKQYLINTYGDLITGIYSTRDTNYQKQIKNKLIELGYETHGVDLIINTLSSEFMDTNFKCLNPKGRIVDLTTTHLNPNEFIDNSRYRYNIGYNSIEILKVGKSTIKKLLQSISKSIENETLNALIPITEFSNSNIKKSIESIKERKHVGKIVISHDTDIIDKLIEKESMIDYSILKSDYKIKNLGKNVLVTGQTGLILEVLKWITKYNSTVENIIILSKSSLKWELEFLMNYNNNNNNNNNNNKIKYHFKKCDISNWNLINKTIDQVLKDNPTITNIDSIFHFAALQINKKLKDIDMNSLNVSHSAKTFGAVNLHNLSIKRDWKIINFILASSVVSVLGSFDQCSYVSACCVVDSLSQYRKSIGLPSFTINIGGVSDRGYLSRHKLVEAVLGGQGVELISPNQLLGTLDLQIQNPNMPTNAFVNNFNWPLFKSFKQKLHQKFDFILNPINVDNSISMENDTNQSSSSTNVKNKFLNKVSELLSIDPSKINTNIKMINYGADSLITVQLKNWVDKEWSPHLITIQQIQSNSIGMVYQIINDSLDKKKKEMDEKLLPITAKTTTTTKNDPNDKTEYKYIAGGDCCREFSIKFHYSSVVNFII", "length": 2471 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54LI2-1", "protein_name": "DNA replication licensing factor MCM2", "gene_name": "mcm2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSQNNNNNNNNNNNNNNNNNNKRKTKTPSSVNHNNTKINEDKDLYNFIDKIRDKTDKSHLEDEYDEDDNTKDGKFNKVEDEIKNDIDSEEDDDDIIEDNEHLYDGDEDSENLSSEGEGDDLLDEDLQDQDEEEVLGDEDNHYEMEGLDNETYEDIDKDKKTEVDSILTKRDREEQKTRQATNRHQYRISSFLLDENDENMVDEDTENNKLLEKRKANLIKKRRETIRQQNDNIKKDYDGSVPSFKDGFVNSERYFEDGDGDDDDDDDDFDIGDNGQVVNLEEPDKDKCLREYVCMSGPRNEISKQFAKFLLEFKEKDGFNPIYQESIQKMCAANKESLMINFTHLCASTVFGVWVAEIPTEMIEIFDEVALKVVLRIYPNYRNIVKSIHVRITHLPICESLRDIRQSNLNKLTKVGGVITRRSNVYPQLKHVKYDCVKCKTTLGPFSLDGTFNDSKPPIGLCPQCQSKGPFVMNSEQTVYRDFQKVTLQESPGTVPPGRLPRTKDIILMDDLIDTVRPGEEVEITGIYKHNFDLKLNYSQGFPVFSTIIEANHINKKEDLLSSFILTDEDEREIRKLSKDSNIAQKIIQSIAPSIYGHEDIKTGLALALFGGTPKDVNNKHRIRGDINVLLIGDPGVAKSQFLKYVEKTAHRAVYTTGQGASAVGLTAAVRMDPLTREWTLEGGALVLADRGVCMIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTTLTARCSVIAAANPKRGKYDSGLNLLQNVELTEPILSRFDIICVVKDTIDSFKDRELARFVVASHINSHPDNQNNPENDYLNRATKQSPISQELLRKYIIYAKRIKPRITDIDKNKISQLYTDLRRESRAGGFAMTVRHVESIVRMAEAHAKMHLRDYVTDFDVNTSIRVMLDSFINAQKNSMYKNLRTKFAPYVIFQKDINQLLTQLLQTLARDFSNYHFARSGDIPDQINIPYDDFDTKARELGISDITSFFRSNEFTSNNQFTLKKDKSTIIYYRNK", "length": 1008 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54LX5-1", "protein_name": "U1-type domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKITESNNNNNNNKKDNNKHWCKYCKIFIQDNISVKNHEEGWRHKNNVTRFVSTQNRDKKYQERDQKEAEREINRIKNTGARSFREKDLSRVLDEKKHQQQPQQQPQQPQQQQRIFNNNSNNNNNNNNNNNNNNNNNNNNNNNSNNNNNYHQPQYPTTTTTTTTTNTTASNKNCDNADSKFKEIQEQQRQLLSNNDYYNYYQDRQQLIYDYYQNEGNQPIPEPPLNTSLYGYTESPLLKSRLDSSTDTLSSSSSSTIISPSHQKKRKQDDTNSPIPAKISKDECVNNENKDKSNEKENELNNNNNNNKSGEGEEGEESDDNDDDEEESGSGSESESESSEVDQSESIIGQWQTVDPIESAFGSTRKDSDDEKDKKDKKNKKDNDENKRDEKDYSDVSDADSEEESVNITKRAMANHKKPITLTNVISPTIPSTSKNFESVLSFNKSGVFSLNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNEPPQPTPQITLKFNKPLKQRNTRKTNIEDKQS", "length": 514 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54M95-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKLISILFFLFGILFFLKNVESASDVVCSFGYQACGNNCYSPSSGQKCYPGGVVCSFGYEACGNNCYSPSSGQKCNPGGVICSFGYQACGNSCYSPSSGQKCYPGGIICSFGYEACGRSCYSPSSGQKCYPGGVICSFGYQACGNTCYNPSAGQRCFN", "length": 158 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54N59-1", "protein_name": "G domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDLDYAIIVLRHHLESNGRFFEISKDDVKNRVTIKNKLTQEERYIDFGEIQNFIQYDEFEYNLLANGFQENLSILKNSILPLTKAPDSCSSNRGKTIGNSSLLINKVNGLIDDDKDTIYLLLIGITGVGKSTFVNMVVNYIEYSNLKDALENATLEQIYTIASKIEIQDENKTHKFSLGDVEDYKIGSSVTQYSRQYRIKLPDGKTLCLIDAPGVGDPQGTLQDNKHFENILHEISSLKKLNAICILMRPDETRATVLFKYCLNQLLLHLHSSAKDNIFFCFTHTRGTMYKPGPTRAILEDHLKKMKDQSDIEINANEKTFCFDNESFNYLAVKKYNATAGIETNFSEDDEFDFGRSWDRSSKEFKRLLEEISKVQPHDVANTICINNARTMISNLAQPMSTCISNINTNIKLMEQQSEKLRNNSIGDESLLYIPVSVVIAEKLENSLLVCTKNGCSSNTDNPCNIDVVSPKWYSSLYWCDNINKMGTCKKCSNTGVLPCLWFDHQVVTIKETPQLNQLPGTDKKTIGQRTKSEIFNERELLVTKMGERKIQFQEEYDTIKTAIVDFSVFLWHHSLIKFNRYYEDYINMQIKQLENSENSQELIQKLNEHLSEYKASVEEIKHNVQNNKASVKTQKEIFATFDKLLTLPNVGYIIQNQIKLKQSSHYKSEAVEIDLFSKMKNKTKQIIK", "length": 689 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54ND5-1", "protein_name": "Multiple inositol polyphosphate phosphatase 1", "gene_name": "mipp1", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MMVKIKNIIILFCIFGLLSNVSSLSSSSSSSQSSDNNGNLSPIQDYDLEFLSKHLTTKTPYWILTKNGDSNSQGDGSSGNSNSNSNSNSNSNSNSDSSNEPPEQCKLISIDFIARHGSRMPVLNSIEKLKEMTTSILEYKEQVNQGFNWIFNYSVPYPSDIAGNLILQGQYEHYNISKRLLKKYPLFFEPMKYKPQSYSITSTAISRTGISASAFSYGLLQGTGSLGVDGFQPVFIETASLDQDILLRFFATCNQYVDQLKNGTLINKDEQTKWNQMVFPNISNEISERLGLSDIWLPTSNVISDIFEACAYEISINNISDHWCSLLSKQNILDWEYSQDLSNYWLKSYGHEINYQIATPLLNDILSGFDIYINNNNNGSSSSSSSSSSNNGDNSGSNGSSGSGSSTSTSSNDNGSTNNNDNKVEPTSILRFGHAETIIPFISLLGLYKDEQKLFANSSTEQIENRKFRTSVVSPYASNIAMFLFDCGSAADGFKILVQHNELPVLVPGCDEIYCDYQQFKSIFKQGIDNFKWNSYCNINDDDSGSSGGDSGNGNGNDSHSKKSSYFLAIFIPITFLVGGTIGGIFTYFSYEKIMQVKNRKKLTQYGNDEFISSPKSKSFSFKPTKFDSRSPLIQ", "length": 635 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54NT2-1", "protein_name": "SH3 domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSNKITTQFARTRQMLFTKTGHSEETIDVQYHYEKERTFSTEERLVKIQKNSKKLIELYKDLNKITTDIAQDACDLYDTQDPMWTPGSKLRDVATNNDKHLLDYTEQMAEPYTKPLSDYISQYKEARKRTEELTTRKVDMDRYKNEVGKLREKGAGSSSKAKLAPTEEKLRICKEGYDSLHEELLNDLPRLNEDKLIFIDYLVASLIKYQSEFHKKVSYEWSPLPSLTKHVDEYSGRDHQPVITSVERSAASINLRSDPVFKSNASIKMKPGAQDQQQYSTVDKDIHQSPNPSNLNLQKSTPNPYGGASAPPPLYGGGGSSTATALYDFTGVDSSELSFRAGDIITIHKSEGEWWEGELNGIYGFAPGSYLRMN", "length": 374 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54PW0-1", "protein_name": "Annexin I", "gene_name": "nxnB", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEYKEKEINTSSPSSPSKTQISNIENDSISEKAQEPISEKVQDPISEKAQESISEKEHIESNNVSEIIDLIKSGDQHLNNNNNNNNNNNNNNNNNNNEEENQEINYNDNQLSNEEIVEDVKNSNINNNNTIEKGNSSQNNNKNNNNNYHTEKCDYCLICKCYDYGEITHNIVEDSEILKQSIRYSYVDDTSINSILAHRNYAEKEAIMKKFNDKYNKSLETELASHTHQKYRRTLISILTEPSIYDTLNIENSIKTKNSNTLLEILLTRTNEQKELIKRIYLVKYGKNIEHDIIAKFSNGANVNGNMMKQLLISMLNNDRDSNSNQSLDMNLINTDSNRLYQAGEHKKGTDHEVFIEILSKRSFSHLSELDRVYENSNPKGHSLRKAIELEFGVSKSIKQVKISLLDILLFSKEPSKYWAEQFNRALTSGSWGINEIDLTRLTITQQHQASKIKQAYISHYDNSLINEVSSKTSFRYKKIILSMLTV", "length": 487 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54QB4-1", "protein_name": "Kinetochore protein Ndc80", "gene_name": "ndc80", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MHNNNLTYQQYQQQQLLIQQQQQQLLYQQQLLQQQQQQQQQQQQQKQYSHGRPSTLGLPSRKPPPMQPQPQPQIQAPIQLTFQQQQQLLQQQQYQFNNNLNTINNNNNNNITNRHSMVTPSTNLGGRSSLGPPSAMLTNNNNNNSNIRNTTFISNSGGNNNNNNNNNNNNNNNNNNNNNNNNNNNNIINNNNNNNIHTQVQPKKSIAPSKSNTISSNTTTTTTAASSSSSSNPSITLRQETRPVNDSKFQSQCLLRLQQFLSQSEKGYPRAITKDNLMSEINGLMKFLCLHIDPHFKLPTEKPEEEIISFFKMMGYRSAGFTKRVFSQVGNAHTRGHLLGAIIWMVELIEYDQIIRQMDSHIEREILNGNTIDENGNLTTTTSATNTNEDGNFNLTTQIFSKHVFKSYEAFLKGDDGNHVDQFLEEKFNEVNELIVKECEESMERQKKIKQEIVNLTQYITNDDIDQLNFKLEQTNQEIIATHDLINDNELEDQKLDQEIDQNQTHFQELEIQQKEHQKKKQEFESRIQIQQSNSVDAKRINQETFELKEELDKVQREQSRHDQLKQEKSKEIKQSINEIEKLIQSYKEICCKASLVTNDNLIIEKYRIIFTHTLNNNNNNNNTNNSSILNISNNIINNNNNNNNNNNNNYEEGIISISDLKLVIKNLQELNLEISQNISKIKQDLLKTSNLNDIQKESISDKELELARIKQKHDKQKNILKQEKQDQTFDITQREENIEQLKSSNKKLIDDGVRELEKTIQLLESQREEHSRLKIDLKQSSEQMKLQYLKRIERFISHRQLIGSQIFDTLRQMEELSLTQKILFPPPPPPPQLSQQHQQLMQQQHQNNTIDIDE", "length": 855 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54QD2-1", "protein_name": "Probable cytochrome P450 517A1", "gene_name": "cyp517A1", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEIINVFLFLIILFLVKDFVKKNKKIHTKSPSGPIAFPILGNVVQIRFWELFKIQEHELFGGYSKKYNGVVRAWFGERLFFFVSNYDVVKYFQKDENFHNRPSVLVPGWRYASSNGLGVMSSSDDKWKRAKSSVSQSLRVRTTKKLMEEKAIEFIDSLEKISNNNEIFYPKGHIQGYACSMLFKYMFNQDLSVESGMSRTIGNAVEHVFGNLSKLTAFDCFEIFSPLYDWFFTRRLKGCDIVRQIISSQNENHLKSIDPSKPRDLMDDLLIEYGLNEITKEDTMQINQICFDIFGPAVGTVTITMNWVILQLCNRPELQEIAYQEIKKAVKDDEYVNLNHKQNAPYIVAFIKETMRLCSNGFGLPRTAKNDQICGDFFIPKDAIIFINYLEISQNEEIFKNAKEFNPTRYLDESLPVPNIHFGVGQRACPGRFVAIDKMFLGISNLLLKYKLKTQNGEKIDDSIQFSVSLKAKDYGIKLEKRI", "length": 483 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54RM4-1", "protein_name": "Peptidase S8 and S53 domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKVILIYFIVIYLINISFSLKPYQQQQQLHNFNIIENNNNNNRNEKVIIAHPKIPPYWLIENEISNPNDLISFKILLKQNNLNKLNYLFEEISDPKSKIYGEFLSINEINELVKSSESDFNVVLEYLKSFNIGNIENGSEIKVFSDYILVETTIEKVSSMFNSKFSNYKNKNNGNTRNRLNGPAYLPKQLLNSIDFVTGLSEFFENNFKIENYLNNNNKNNGDSDSDSGSGSGSGSSNSYNGGLDDILITPKVLKSYYNVPNELIGKFENNSIGVIAFNDYFSMGALELFDEKFNITTTKDNLKIIGNDCLGKGCDQYESDLDIQYIRSMGENISTDFISFNDAQWILDYLHSVLLMEKPPLVQSISYGWAELLQCDVSNGCSTFGYDSKQYVDRTNSEFQKLALLGISVLVSSGDDGAPSMGGSSGNCPIDGTVYCPTGGCNHTKTMCPEFTIYNLNGGSDSGGSSDSYCFFPMGIASSGCTNILGDPSVLDSGMKIFSEKNKQCNLAIEYDRTNLPHVYSECECKDLVNVTFRNYHFTQYQFNENNGALFVAEYPSSSPFVTSVGATQFLSRDEKITTEVGCTILQGAKITTGGGFSSFQSQPKYQQYAISQFFNTSFNSLPPSFSYCPTNRGVPDISMVGHNYKIYSSDGNNKDFNQCPCKSLPVDGTSCSSPTLAGLIGLINDQLLLNGKTQLGFLNPLLYQMAIDEPRIFNDITGDSSNRCSRSYCCLYGWSTSSNTWDPVTGLGSIDFNLFLSYVLKLKGI", "length": 767 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54RX1-1", "protein_name": "Translationally-controlled tumor protein homolog 2", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKLYKDLIGNSHDDLLTDRYEIKVGDVTFEVKTKMITKDLNVVVNNNSLGGSISTTVDNNNSITLSTNLEDEFENVEAAGTFQINNLVEQLRLVETSFDKKSYLAYMKLYIKDLINHIKQQPSNSDNEKIEHIQKGIQSFVKTMMDGENFKKYSFFTGSSMDANGLVALMYYKDDDPTTPTFVFIKYGLLQVDV", "length": 194 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54S19-1", "protein_name": "PHD zinc finger-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKNCIVCSKVGQYPLNLVKCYECKSYYHKFCLQSTKIPRGEWYCSSCEIERKNKKNKKRKLDGAGKKNKKNNKDDDDDNDDDDDEGENDEDDEDHQDEDSGEEEDEEEDEEEEDDDDEEEEEGNEKNKIKKRKRIPINQSPSIKKRTKDIDSEEEEEEEEEEEENDSEEERRIQKRKNKIKQQQQLKMKEKKQREKLRKRRRRTRSSRKDDNDQDDDDDDDDNNSNNSDDNDQDENKNKQKRKRRKDKKKDDDDDDDQEEEEEEEEEIVTGKRKRRSLNKVQPNQHLNNENEEDNEEEEEEEEEEEEEEETDSSEEFLENLVCSSCNTGKDEDKILLCDTDNCSRGYHMYCLRYPITSVPKGDWICDFCRFGDISADLHSADDDEDGAINSQKEIEKQKQKQKEKEKEREREREREKEKEKERERERERREKEKKDALRSSFSNIPIPKINNINGSNGSNSNNNNNSNNNGSGVNRQSPPKVISKKSPQQSPKPLKSPTSSSSSTTSSPPPLHQQSKVTSKISPNSQQSIPTINSNINKSPPSQSKNSPPLKPLTPDLKKQIPITNITTSSTTTTATTTTTTTTTANTSNVATTTTLLKPSSQKKPTILSDKKQLNTSGTNLPMNGKKKEDLESSASHSILDMIPPNNKLFNNSIQSAPISWDLSGSQHKLSTSSSSLPNSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNIKLQQQLQQQQQQLHQQLQQQQLQQQQQQLHQQLQQQKLKQKQIEEEQEKEREQKRLENEQKLLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQEFIDQKELEDKLLSQFDNQNLKSPLSLTSTTSSTLSHLPQSTFESSTILSNKTIKQKWKSRILFETDQICQCEIIQIYGMDFKVNPFQNNITSKTLELSFNQVSFDNLPKPIRDEFITKSSTPSTCLDIGAIDLPNSALLIFLPEIPNQSSLYHLIIHFIENRVAGFIDLSNDLSLYIYPYQTSIISLDLIGILIDKKSLSPPSLILNQQQKQQKQQQQEQEQQNQSFDIKNICYIGINHISMNKILTSQGKNYFSFSNFNELTLSSDIKNFDLVVVDNKMVNNQTINKEINNLMQLQPTTNNNNNNNDINNNHDTLLLVIKDVEFSKWLVSQKKFPNSLEIQKIFQQQILFKQSRCIFLLDNSIIIENESSYFVEFISSFGKFKNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSSNDWTIKISSTIFDELLPFGHQSNVKKKIDEIKRGINQQLIVSYDFSPMVPKQSSDFLLLALRIAHSKKYKQVFLITSNKIIQNQSKRYSNLNLNCLSLEGGIDYIKNINNKFSLKI", "length": 1361 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54S56-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIAKTQIKCTTIYAPAKSNERHEWYKENLTEEILHSDIITGDFNVDCSVDNNLNKYIKTIFDEFEFTEIKNGITFPRNKSTIDRVFVSKKILHLNPIVTTKEIKLKSDHNMVIIELKIPEYEQQKKGERLWRQNLETLKMNSTSLKINKTIKYYNKKFEENTSKWYKLNICEQWLKLKDEIKKLSINIEIRESNKTKNKLKELAEKLETAKDSRAIFLKEEINNILKEQVRIKQANQTNTHINNKETPSKYLTRRLKVQRKTNEIPQILDPSNNCLVTKHEDILEVARRYYENLYQKRECNEDTHHELLKTFNKRIDQKILDEINQPIEGYEIRLGIEKIQEGKAPGKDGLLPTFYKNHINEILPIISKLYNHFWNTTIPKDFKQGILITIYKNKGDPNNLDNYRPITLLNVDYKIYSKIINNRILKFLNKIISPFQTGFVPRRLLHDNIITLNSTIEIIKREINTKEDMEPIITFYDFEKAFDLFSHNAILRTLAHLKLPLKMVLTIMNLLNESETSVYINNSLSKSFTSKRGTKQGDPISPTIFALVGECMATTIINDRCINGVTKETIKILQFADDTATIAYNFMDHFLMNEWIKKFCQATSAKINQTKCSCITFKWNTRTLYTVIKSNERYLGFDFNNKGIKSKINTISDNIRAKLVTWNSTSSTYMGRLIMAKTYALSQLTFHTYINTTPQHNSIENNIVKFVFNTKSKNSLSLQRRQNNYINGGLNLWNLKTRELAQKAWLFERYLHQRVSNTPSSYIKLWEEELKNNNNNKTTTKQNQLQLHWQCKQAWTQLKTPQNKQTHYEHLPKLKKIYEDMMTTQSPEHNKFIPTPGQKEIMTKINSKHLPFKEIKKIINMKGRDLLWRYTLKALPKIYNMPCQQCGEDETSEHIFFNCKAHIKNTQEIFNYTLTKCGHTTHTWNVKILNHLQIALVANLIAIIFDKIWHKRNKLIHDEKEIIIHRQQVIRELIKTQRAAWDRTQAVINKTLRIKSKQRPEEQNKLDSLISLKLLQFSRQWNSPLHAIELPKHLKKYNNSLSTFYK", "length": 1047 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54SW0-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "NQAKSSTIQQPTQTQQSNINNNTAKPRAAPPLKLVITNSNPSLKQKPQSQQTIPQQSVPQQSIPQQTIQQSVPQQQPNQSQQVNVNRTINPQQQQQQQQQQQQQQQQQNINRTAPLPQQSNYKPQPGVIYQQQQQTQYRVGTPLTINRSPMVGMVSKQPMSSSQQQSQSQQNIQRVPCQGKCCAGLAVKPLVPINSITAKPPPYSTMGPRGPISGGFVRTSPTGAIIGPSPQQQTMSRAMVNSMPIQPQIQIKPKPSPLNNGGIPITTTTTTTTNPLNKSSPSTLTQSSNTLASSNNNITTSNSLSSSTSSLPTTSTTPTTKPKSKPRSKSNSNSQTSSSTTSSSSTPSTPTTNSTKNKENTTPNKGDDSGTDNEKSSLSNSSKLLPTAYTMDQVLPFNPNQMFLGPEDKYIKSATRTYHKIPTNPSVMSNNRGAEIPSSLEYILDIPIIHDEPSSKNNPTWGRLILDALRRLVANKKTTRITERLKLDNMYKDMDSRSNQDKLDWKNGLVNEAQLNYLLSFLSNTIPFPDTPEKNKNKYLSSSDSQIINSNDQSNSLNSNNSSNNSTTNNNNSSTTTNSTNNIINNNNNNNTSSVPNSTNNSNNSSPEQQDVIDMELKLEPDNSMNFPIEINMDSLGSYIDDSFTFDNSSYDDTATISSDDKNLPITTVMPPTTSTTSTPQTITNTIPTTTPTIISPPTITTTTTTTKTTSPPTITTTTSPPTITTTTSPPTITTTTTTINSITPTTSTSSTINSNTTPMLDIVIDPVISLELLDENHQQQQNKEVKEENVHSKQQPPQQQQQQQQQQQQQQQQQQQQQQQQQQQQEDFMIQVQTSDLETQTQIQQDKEEIQVKPIVDSKKSGNSPTQIQQQQQHQQQQHHHQHNTLTQGFEFGMMMDIMNSPSSTSSMKRKRDDVDQPINQINNSSMVVQQNNDFFSDFNTIEAPFSSSHHSSQLSFQTPFSPDIVIDSDFQNKKRIVS", "length": 981 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54T36-1", "protein_name": "Probable polyketide synthase 19", "gene_name": "pks19", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEFGNKEIAIVGIGFRIPQGKESINNGSVSHLWNNLKNGFSGIVETSERWSDNINLLGEVNNKFGGLLPLKEWSDFDPVHFAINPSEVPLMDPQTRLLLKCTWEALEDAFIDPIDIRGSNTSCFIGCSTLDYSTTNRDFNETSENYFASNVLHTISNRLSFSYDIRGPSMTIDTACSSSLNSITMGFQSIQNGTSNLSIVGGASLLLDPYVSKSFSFLNMLSKKGKCKPFDSEADGYIRAESCGIVILKPLSDAIRDGNNIYCVINSFSSNVDGGGLNDKSNFYSPSKQSQSDNIKLALKSANMKASDISFVECHGTGTPTGDPIEVEGVSMALNSSTTSTPSKPLLIGSLKSNIGHCEAASGVASLIKCCLMFKNKHYAPNVNFDQPNPKINFKDWNIKVVTEAIPFTNINEKPVSMVINNFGVTGSNCCLILSQFIEHSISLNGNNPSYPIESQQQIFLIPFSANSVKSLKNYEDLIINDNNLSTNSFKEFVKNQIYSKSKKLYQRSVLISSNWDQLKTKNKYFKTSNDKSSNITIKRNQPLIVIVFGGQGSQWNKMAQQLYECEPIFRSSMDKFNKELSKYYGYSVLDKLRSIKDDDIISIHQPIIAQPSILMLQISLFELYKHWGINVSFIVGHSLGEIATSYCSGMVDFQTVCKLIYHRSISQNNTNGCGKMLSVNISHSEFIELYSNKYPTIEVACYNSPTSIVIAGNENILKEISLDLKENNIFCAFLGSLSSFHTSSQNSTKNEILPLEIPSRQSTIPTFSTVTTNLFNHETTPFNSSYVYENIIQPVRFSQTISNLYQHIENNKLGNELIFIEVSPHPSLSFYLKQMIPKSSSYFNSVSVLTSTNKKNSNDLDEIHSTISQIYCLGYDINFKCQFNHNDDDVNSIRNNSTIILPNYQFDEQYYWKVDINFEQYRLNGPNVFNNLGKSMINYSSNNKSYESIIDINRNPFKYLKDHIVKGKYYFPGIGYADNIMKLYPNKDIVINNLEFLAPFVLKENVKHILQTNVYQLGNTDYRVTFNIKDNKANQWVQTCTGNFQLISLKDNNNNNNNNHSSKYNINQLLSECNFTTLSKQEVYKYSKLRSGITHLGTFQGIEEFHFGNDLTIARIQINYENFDINGKPVYQTFDKSFFNIALLDNCIQAITGFITNSSQFVFERLEGLKVYSENIPTDKLKYKNIYCQAKFISLEADSYKSSVLVLLEDGTKLLEIEHISFRSTLPLIDELLLNNPTNELFTNNLQCKDSLVNILSIDNNETSSSSGSSNTVTEIIKQTIKPIINEKIVFRILQSFSDSELSKQIIEALNQIFDNSLQEIDIEFTIIDNSNDKLPTLHDSSLIFKNDITQLKPSYYDIIINNNNDETIIKPIFNILSSNGLLLLIIEDDIGIRFNINNLIGVGFNENKIQKSNKVIQSQKSTILSNELTVVPNNKNDNIIIYCEKHSKYTNEFKKLISNNHTNRKQTTISNINEFNQLLPSITNDSIIYFIKSMEQLEMNNFKQITMEYIEINQQLLKHSLTCKHVLITIDSQIKNYLSSSIIGASRYFNEFPSLNLYSIDFDNQLSISSLLNKIINQLIENSNNHIQREYIIRNNSIYYEILKNEKNIKSNFNSNSFEDNDFMTLLDSTNLEYKLASKPKKLKKNEIEVKVLATGINYKDYLIYRGLVVIDENVSISKNPLGLEFSGIITRISDENKNCEFKVGDNVFGVSHDATASHVITDVLYVSHKPNNISHIEAASLPIIFSTCLHGMFNIGNFNIDDDEVILIHSATGGIGLATLEILKWKGHKSPIFVTVGSKDKEQYLIDNYGSFITGIYSSRNKNYVNEIKSKLNQLYGTTGKFNGVDLIINTLPNEFTHSNFLCLKERGKIIDLSITHLNNNEFLNFNNFKFNKSYHNIEFMHINKRVVSRLLKSISNALNENKVKLIPITTFQIENVKEAIEYINQRKHIGKIVLDHSCSNGSIGSDGLLNQLIESDNNEKNHTILKYDFKIDTKNIIGKNIIITGQSGIILEILKWLIKYSPPTESFENIIILSKSSLKWELELLINKTISRKDNNTKFHFKIVDVGDSIEMRKSINQILLENPNIDNIDSIFHYAFTQVTKEVEEIDIESLDISHNAKTMGAINLHEISIEKSWKLKQFVMASSIASLFGSFNQCTYVSANLVLDSLSRYRKSIGLPSTCTNWGTIKSSGFVSRNDSVSKMLDDQGFIPIPTNIILGSLDLQLQNSNKYSNLIVSKFNYDSIKKFASETSTFQRLDFILNSIKEKDNDNNGGENISISESIQMKFLNKISELLSIEQSKINTDIRLGEYGADSLTSVQLKNFIDKENKSNVITLQQLQNNTIGVNIQIILEQIKKLDSNETKGKSKKIIKKDSAPSLEYWRNEMKLDESIQAIKMNPIDFRNDSKVFLTGATGFLGVHLLSNLIKSPNCSVVYCLIRNKKSEPNPINAIINNLKHHKLYHFHNEFELSKVKVIVGNLASPLLGLSKLDFGFVSNQINLIINSGADINLASNYEESKVVNIGGLIELIKLSTTGDYQKPIVGFSSISVFFESPNCKEFDEETVIPTIENINNLPGGYMKSKVVVENLFREAAKRGIPSMLIRLPIIFSHEETGIGHDSDFFQLIIQSCYAVKKYPNIDKNILTSPIGWIGLNTIKMIGNEKCWNKSSSNQLNIYSLNSEVSSIKSSFSFLEKQYGCEMVEYEQWKNIINQSKILSCIKFKTFHSLDRLNGVYNLGHGFGVSKKTKELLQSMNSYEGGMVNEKIIQNHINYIFKN", "length": 2778 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54TD0-1", "protein_name": "Peptidase S8 and S53 domain-containing protein", "gene_name": "V4-7", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MISKTSLLLLLLSIVALASAISVQRVPIADVTSAPAHFVQNKLAKSYELVQFKILLKQRNLDILEEKFWDVSSPKSENYGKFLSKEEIDSIVAPSPKDVKVVVNWLIDNGLSKNEMIVHSDFIQVRTNVGKASTLFETSFAHYSSSRTALKRIRVVGQASMPMHVLAKVDLVLGLSDFIEDNKMSESMRATKKQVQGSTVSITPAVIKQYYGIPTGQIGVESENFQSIAAFSDFYSSGALQFFDQKFGIDSSTVRVKNVGQNCIAQNCDQMESDLDVQYMTAIGNNITTLFLSSGNGEWIIDWATAIQQYNPIPKIASISYGWAEVEQCEITNSCSTLGIDSVVYVARSNVELQKVGLRGVSVFVSSGDDGAPSFGAASGNCPIDGTKQYCPLGGCNHKSSQCPMITIMESNGTQCFFPMGSESNTCQSMLQNQNIVNGINEFVSSNSKCQVALEQDTQQNYHIYSSCTCDKLKPYSDSDAGFKIVGYSYDQDAGTLFQPDYPASSPFITSVGATQITDVTKPEIVCSVATGAIITGGGGVAITQAQPSYQADAVATYIKSGTLPPSYSYNATNRFYPDLTLVGHAYEIAVPNTLTSNTCPCALESVDGTSCSSPTLAGMISLINDKLIGAGKPTLGFLNPLLYQAAKEQPNVFNDITTGANNCNRAYCCQYGYTATTGYDAASGLGSINFKNFEQYVLSLN", "length": 702 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54TX3-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MFNFERIDHGSGKGTGIAIENRDTRKGHISINFKDDDGRILSIKYNSFNSINILLIYAPATISERNTFIINSKSLFKKYNSINHQIIAGDFNNNHDCNSFFGTELRKIIDQDMLLDTGIEENTPTFPRSMKRLDRIYCHPTLLNQNSKLVVHNTVFNKSDHFPITITIQTNRETTTTTTTKLERLPWTLCKEILNNKHIHDGLSELISKNKDKIKSVEEWTKFKNNVIRDYFKKEQNKIKKEKNKRKYVIHKLLGNSDIIPKMRKELNEEISRILEEERKVKAWDIKLKLHLHQETPSKYLTSILKSRAKDKSIFQIKDKDNKTISDKENIAKRFVEFYQDQYEEKEDNEETHKKLLEKWEVDVDLIKKLEIDRPIRIHEVTKAIKTSSIHKSPGLDGINALFYKYHINSIARILTIAFNDLLTNKKEIPTKFKEGVITTIFKKGDELNISNRRPITLLNTDYKILSKILNSRLLDITSKIINKFQNGFVPNRFIQDNIQIMKEVIEISNKRKNNTLITFYDFNKAFDSISHKSITRTLEHIGIPPKFTAILLNLLKDTKNKIKINDFLVNGITIRTGTKQGDPISPTIFALVLEPLLIDIINDNTIKGFTLPNSKSLKLTAFADDIATFTNSTEELMKINTKIQKYCSATSSSLNKEKTVMIAIGDKPHDLPFQESTVPERYLGLNFTKTGLNSKYNTLIQEMKNNLIKWKSQAITMKAKMTILKTYVLSKLTYHQYMDNLNEEQIEEINNMTRWFLFSSVKNTYTEERKYKTMMKIDRAYADWKEGGIKLWDIELRHIAFKIWYMNRLLHNNYNNNNNTLQEWYMEQLSRKKAHTSTLNDMCRHWGVFRVKFYQNHPKINELPDCIRNDNDEPLKLKEIYELMIKDRHPTPRRTEWQKLWAVRYNTAIPKVFININSISHQKGRNTLFRFFSRSLPGINHERDTRCKICGHLFRDPYSHLFTLCQDILDIEKTIISTVNKLSFIKIHRWSMDTLDISKYNRTERIFPNLIGIIAHQLWKIICHKLFNTDESKPEPKFEQKVIETELLNLIETEKFITLKKIKHDEAILKNTNQDLHKYKFNKAWQTPAAPNPLPI", "length": 1097 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54U20-1", "protein_name": "Peptidase S54 rhomboid domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIYGDTREFRNIHFHLNNIRIVGAIFGQDGFIHKKIPLATKVISIICSILFALSLVAPSMFGSYKTCLSIESLTNSFLDNLYRIILSNFAHLSIYHIVYNMITFLDLAKLERLTFGTLKYFYLLFLFGIITNLICLFIYFIGRNNVCHLGFSGVLFALIYIESNSSGRDVFLFNAVKIPSKLYPWAMLILAHVFVPRSSFIGHFSGIVVGILFIKGYLDIFILSNQKLSEIESSQLMNIFTTKNSYFPIIKFGGSRRSYNTDRKSLDGLFFELKNLFNPQQQQQRQQQRQQQQPQSPQPQQPQQPQQQPQQQPQQQPQQHQRDNFRNDNNDNSNNYDEYDFSK", "length": 343 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54VC1-1", "protein_name": "ABC transporter C family member 15", "gene_name": "abcC15", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIKKIKNIINKIINFFSTIYILCKIYLYYNIKNRYEAYNILSVYGDDDFFNKPCPEDSSNWKDKLTFKWVERIIFVGFFRAPLNLNDISDLPSSLKVENTAPLLKDIIFNDSTIPLIKHIYSKFLPRNYIATGLFVFVSVFSFITPLILKNFLSYVEKIDEQKHIYIGIIQCFLLFLSSFINMASQQYSYWFGFKTSLEVKGALETIIFEKMTKLSNLSKKNYNIGSMLNLMSVDTDFFQYFFCHYYIEIFLFPIQILSLLGFLIYVIGIAGFVGFLVMLITIPLSSFLGTQISKNLSTSMGYADTRISLTGELINGIKFLKQYAWEKMFCERIEEQRKLQLKYLYIRIIYWVLVQIVTQASSGLVLVSTFTTYTLLGYEVSLEIAFTSITILQNLRRPIESLPDCLHKFISLIASAKRIETFLQSSELQNQPFIHNQSGLNDILIRNINFNWNEHNLKLKNNKNNQNNNQNKRSIILSSGEQFEITNDFTFDGIDIQDDNYDYEKEYKINYNNNEEEENFMTDCLLKIKPLIKDRRLQQQQADYQDLLSINLPPPPSENVDFKAPKGLLTIISGGVRSGKTSLASGLLGEICKAVDKSSPDSVNSILSTIQQPFLQSTSFRENILFGKPMNMERYIKVIEACCLAPDLLAMGEGKDLTEIGERGINLSNGLKHRIQLARALYADSDCYILDEILSSVDPEIANYIFQHCIKGMMKGKTVILVTHQIQFISSADHVVVVDNGVLIQGTYLELLRMGIDFEMILKEKENRIEKQIVQLQEDEDYYEEVEILDFTMNNNNNNNNNNNNNNSNFNGNNKLKRSSISLPKGISIESIISKDFDQTTIEKAKLFVQEDRNKGDPGWIIYKKYIRMGSSISFFIFTCIIYLTSQIILLLSDYWLQSWASHDRLNVSEPTDVHYLLIYLAYIGGFVFTLGVRYLLIAKITFGSAETLHRSLLKSIIRAPLTFFEQNPVGRILNRFGKDISDIDILLLDCFSDVLYCGACLVTSIGIIIYISPYIAIPFVILIAINYIFQLFYNYSVLELKRIQSISRSPVYSLLSEVYNGLTTIRSFGQQERFFNMMKDNININLRVFFYNFAVSRWIGIRVEFLSAIVVLMSALFSIFNDNPGLSALGVTTALGITFNLNWFMRQFGELESRINSVERVQSYISIPKEKETNEDEFIQTGFIWPSRGEIEFKNVEIRYRPNSIATLRNFSMKINAQERIGIIGRSGSGKSTIGMSLFRMIECSSGSILIDGDDISQIDLKRLRSSIGIVPQDPFIFSGSIRLNLDPFDQFTDNEIWEALSKVKLKKMVSTMPMKLESLVQGGDGLTIGNKQLLCLCRAILRNSKIVLFDEATNSIDFQTTRLIKQTIEENFKDCTILTIAHNIDTILDSDKIAIIDEGELIEFDTPLNLIKDSTSRFSKLIKLNNNQKNKLN", "length": 1436 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54VG9-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKSIIILSFILSIISFSNGTIVKCTSASCSSLNNNCVNHYCNPRAGCYGIDKCVRIDACHIVSCDLNNGSCINTKANCDDGDPCTDDFCHNGYGCFSLPNNKHPSVICQKNCNDNNPCTDDFCDFTNTCQHTLKNCEDNDFCTIDSCGPNGCVHTNISCDDNDPCTSDFCSIMYGCYHEQIECSIKVPCSTDIECNRYNLCETYTCDLISNICKYSTKFCNGFPCINNECMTGVIYN", "length": 237 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54WA9-1", "protein_name": "Short-chain dehydrogenase/reductase family protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEIKKNIFFITGCSGIGFGGLMVKKLLSRGDYVAATSRNKNKLIQDIGSNENDQFLPIEMNLADESNVKEAIEKCIEKFGRIDILISNAAMGILAPLEETTDKDARTLFDINFFGPLNLIRNSLPYLRNNQFLKNNNDNNNSKLNGPRIIIIDSICGYSSLFNGCSIYCSSKFALHAISETMSIELKPFNIHCCNIAPGYFQTSFLSSCLIPDTRIAEYKDTHSFLDEIVKLNGSRFLGDLSKAVDVIIEISLSYSPPNHVLVGSDAFELFDLKYKKLTNDILINKEICSNTDKN", "length": 295 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54WC3-1", "protein_name": "Cln5-like protein 2", "gene_name": "cln5lb", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNKLIFIIICLGIVDKTISSDFKSYNDGIYSFTYDNICSFKNSIRDQDVYELYYVQAPLLYATYGNLLEKINAYHSGIVLYNKNNGPNITIDYYAIPSFEATLFPKSIIKDSQGNYNITWDTHGLIEVTNYINETYWNKRQLIMYDLSGIQIKQYLSWAPIYNKTHTFYNLFNIESDLSISNSSKIYKNSSTCDDFVWASFDVLYKLGGTIASVQSDPQRDDIKLFISSGEPKIVDYNDSIKRNQIASFFNELKDFANLGKNKTALEIFNELITFFNGYFYCYIDGEYYEMKLSKQNPISFTYLPSPIPIGKRNFNEIKKLGFCK", "length": 325 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54WW7-1", "protein_name": "Probable serine/threonine-protein kinase DDB_G0279405", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGCIFTKPSPEQQKFDGEDYECENKKNLNLISYIRNLLFGNNSHQQLYNEIIPTTTSTTSTTTNSVYQNIGLDGYNNNNNNNNNNNNNNNIMNNYGYDDYGYSYEEDEDYYDEMPIPTIVAQPQPQPQPQPQPQPQPQQPIRIVSQNQQIPTTPPQQISQFNITGNKSPSSIGSRHRSKPKETLRAHKKRHKDGHKMVNEYVFVRKLGKGTFGKVKLAYHHDTHHLYAIKIFNKIRLKKQTMGIGRPNAFDDVLKEIAIMKKMNHINVVKLYEVINDPQEEYIYIVMEYIEGGSIMSANETSEDLARKYFRDIVFGLEYLHEQKVIHKDLKPENLLVNSEGVVKITDFGVSHIFDDDDVVRCSRGSPAFLAPELCRNESQPISGKGVDVWALGVSLYCLIFARTPFISKTNSLLDIYDQIVNHEPTYPREISNDLMDLFKRLLDKNPLTRIQIAEIKSHKWTTISGTWPMNELDHLILSVTDQEMIDAISTDHTIKPSDNTTTDEDDSDLSSSSGGESSGIIGSSNESKSMYNNVNSKQKIQNQNQNQNQNQNQNQNQNQNQNHNQNQNQNQNQNNNNNSLIEKSNISIPASSSSISNNDSCYENRNVYIKDEEMNMICNDSVIMDPIKELNKIDGLNYGCDFQIGKEYSDFQYNSGHFIYDLVDENESQISRESANDYYLPFKTNKYLNNKSIV", "length": 695 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54WX7-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MARTDNVQLPLENTSIEFEEEIIDSQNDISQQKNYQDFLKNIPTDLNERKEYISSLKKLIKLEKRNHQQIQGEQPNQQEGLNSDRPPPNHHGDHHHSLPPPNHHGDHHHHSQPPPNHHGDHHHHSPPPPHHHGGHHHCPPPHHGGHHHCPPPPPHHHGGHHHHCPPPPHHHGGHHHHCPPPPPPHHHSHHHHCPPPPPPHHHGGHHHHTPPHPPPHHHGGHHHHCPPSPHHHGGHHHHSPPPPPPHHHGGHHHHCPPPPHDGNEYLPQSQTNIEQCICRLNRKKELLIAKIQSIDSIIYNLECLNKQNYQNNYLPSIQLQPTQQPQQPQQTSIKPQQMCQQFFIPQTPNFPQMNNSAPLMYVSQIPVQQSFNNN", "length": 374 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54Y59-1", "protein_name": "Small GTPase", "gene_name": "rsmH", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MFNIFLSKSKDVYRVTSHKKEVKICVLGDANVGKTNFINQFTKSSFNEEYTPTIESRQNKLYKFNRKQFQIQIYDTAGSKELNLFVSDSISQCEGFIIVFSLNDRNSILKIQHYKTLIKNIFKDVEMPIVLVGTKMDLKKEITISKNECKITSVNNNIPNLFYTSAKNKESIIPVFKKLVDLIISKEKKVKKETESNNIKINNQNKIKKQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHVFKTRSNSTLRMKKYLKLF", "length": 272 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54YJ4-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKKVYQDEEFSFFEIGGKKIADLYVRDIITEIRKRGKEITGLGLKSKYELLCILVNRMKEENPSLNIPPKKRVLDFGSLSSTTSNGILQDSNKFFKKDNTHQHQQQQQQQQQQQQQQQQQQQQQQQQHSNNSDDDDDTHNYNDDSDESDDEYIITEEEEIELHKNLNLGDDENLLTLEIKLLESQLENKKFRKSLLLKDKKIKHLENIIQQQQQQLLEQQHQQQQQQQQQQQQQQQQQQRQEEEQQKEQQQKEEQEQEQSSLKNNLKFKDGANLFSIESISNLYNKILNEFNFKKIITEFGDSSLKIHEEFVKFIILKSINLNHNNNKNNNKNNNNNNNNNNNNNNNNNNNNNNNNNNNSSNNLPNGDVNKNNNNNGEIIELVPPPKIDEFWKLMVLDTVGYQQFSNILGAKVNYDTDINPTRKGYQRLKDMKNLYFPPPPSTTELTTDEIWPNHYLLPIQPSPQKQHIQKQQLPSSSSSSSSSSSSSSSSQQHQQHQPQHKQQHQLQQIQEQQPQQQQHQQQQHQQPLQQQIQQQQQQQQQHQPQQQHQPQQQQQQQQPQQQQQQQQQQQQQQQQQQQQQQQQKKQQQQHQQQKNKENNKENNKENNKQNNKENNKLNDNNLNIEVHEDEGNRIINFLISPDTPLRNLFVAYAKEIGENFNSFKFYFGNELLCQNETPSQLLMRNGTKIQAFYLNKKEIKK", "length": 702 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54YV1-1", "protein_name": "Rho GTPase-activating protein gacII", "gene_name": "gacII", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MVRKLFNTSHKKELILDVDTTIVKIGTPKNVVLLTKWLDANGAIKEEGVFRVNGNTTTMEQIKKNFSQGKDDLTKYTSADIHSMAGCLKFILRELPEPIFTWDFYPIFIKIQCLQDESRKLFFLKMLIHGLPYTSRTLVFQLFGFLSKFSVHQDQNKMTPKNLATVFAPNVLRPKKEEDNFQLMNNQDSIGVIETLIEEFQYISNIQKNTLNSQEIKVKSVLPFDETTNAITQQSLVEDYLIAKANTPQESSSFKKNLPFKKGDIIKLLYIKNDGNFIGEINGITGNLSQTYVDIIDISELAEAFTLTPPPIPTLPIASTILHTPPTSSSSSSSSSSSSILLTDNQPKLCSSTPRINNSPSSFSPSLSSTTPQLLVQQSPRQSPRQIPSISLIVEPNNTNQPSFGHGTLQRTSTGYFSSKPLSISQPINMSKPTNMSPPTHHAMSMHNLPPSNTTRENHLPPLPTKPPPLTIPSSSSLPTTPIKQQPQQPIQQPLTPQNHHHHHHHNNLSSSVNTANTGNCANILSPNSDRYLSSRSQSSVHLSGSSSSSSSSSSSSSSSSSSSSSTSNRKFDFSLKSKSSKNSPSKNLPPQPTTTSTLTPPPPPTITTTTTTTTTTTTTTIATTPPPPSKPLPNIPVKDQQFNTLKRSTIEIPPPTITSTNINNNNNTINPRTLNYSFSSFSITYNNSQLGGQLSQEEPPGGVKSQSSYLDNNNLPSRNTNIPNLPPRPPPLNIPQQQQQYKPLPSPPQLQSPQSSLNQSLQIPLQQQQQVQQQKLTTHYILPPQNTNLSGKNLQRSSTSMLLNKLPPPPFSFNKN", "length": 817 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54ZA1-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIKIMTWNCQGCSTIKSMNQTKNTINLIKPDISILTETNLKKDQNLAQIKNHYSTGGKGKEARGKGVMAINHLEQIEIKNLEEKEGRILKFTAILNNMEINIICIYAPASYDRRKGWFSNNISLEDLEQADIVTGDFNINKYAKIKFKDGSSDKRKFTENETIEFLMMEVGLTEILPNSTTKTTFKDKLIDRTFLSTKMHQLNHSYKIIDKINKSDHNIVVMDFKIPNFTKIYKSPLWKMNSIIIKEDKTIKKIEKIIDHYQETKRKNLNITEYWIKFKKKIKKQCITTEKKRILERKKTLSNLANEHTKTKNKYEKETISNEITILQEEERIDRMIKSSINYINNKEIASNLLTSILKKRDSGSQIHRIKNPSNGEIETEQKEITDCFRKYYETLFKEKECDQETHTELLSTWNPPIDKKKLTEMEDRIEEYEVKLAIEKIAEGKSPGEDGITSSFYKIHQHKLIPILTELFNFFLNNEIPTEFKNGILTSIYKGKGDVLEISNRRPITLLNVDYKIYSKIINNRILKILPNIISKYQNGFIPGRLLHNNIIALDLAMEKSDRNTIITFYDFEKAFDSISHKALIRTLNHLKFPRKITNTILSMLTNTNIRVMVNGQLSESFRAGRGTKQGDPISPTLFAIVCECLSTSIRKDNTIIGIKLNQNNSMKIGQYADDTVTLASNIDDADKMDMKVIKFCQATAAKINDNKCVCITKNPKIKTKYKTIGAKEEERYLGFFFNRKGVISKVDDTVNKLENLTKCYSSVSSTLKGRITILKSYLLSQLTFQLYINEINDIKKLENVNANMLFKGDRWAISKERSRRDYEIGGLELWNMATRSNAQKAWIYEQYLREKDDQNCPPHMEVWKSEKENSLSRIHIKCWKAWKLLHHPRERITLKLNQVKPKYENKQKLKVIYRNMMDIKYKGWNKHQPTTGQKLIQKNINHPILPFREARSITTIKGRDLAWRYLLKALPKHHGENCHSCKEEESSMHIFFECKSIKQNIDSIYQKVCKDSNNTYHGPWSEKVLGKLLTPFSSNLIGAIMESIWYRRNQIKFNDNTTIITENQIIHKIKKARDAEWDRTRKIVEKQLRQELRCTDNRESINRTASIKRRLEKFSHNWNSKLMTINIPEHFIPYCSYNTNYS", "length": 1144 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54ZA6-1", "protein_name": "Alpha/beta hydrolase fold-1 domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEKINQTPKKHKIIEPNRKGYSIVGKNTGKPNKIYFETFGNGPKKILFITGFLSSSKGWCKQIDYFTNKKDQYEICVFDNRGIGKSNIDSKYSYNFSTKSMAMDAIDLLEDTLKWDKVHICGLSMGGMASIHLSSIIPEKVQSLVIACVPNGYFLPFFSMGVFNYIRAFFFTFNEKKKARIFQSLMYSDNYLDEKTNGSDETRSEQMFKKNSTGFKDDGPSFLTILGHQIGYITNRFSKKSLEVIKKYSIPTIVINSKKDSLVTIDITKKQIVNPLKPLNFHVIEGGHLSQLENPTFFNKLVENHVDKHSNWDHSTFFQVEKQQFQRQSFMTQNILYSKNYLSSNTLSSSFLNCNTLRSFFNKIKV", "length": 366 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54ZT3-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIAKTQIKCTTIYAPAKSNERHEWYKENLTEEILHSDIITGDFNVDCSVDNNLNKYIKTIFDEFEFTEIKNGITFPRNKSTIDRVFVSKKILHLNPIVTTKEIKLKSDHNMVIIELKIPEYEQQKKGERLWRQNLETLKMNSTSLKINKTIKYYNKKFEENTSKWYKLNICEQWLKLKDEIKKLSINIEIRESNKTKNKLKELAEKLETAKDSRAIFLKEEINNILKEQVRIKQANQTNTHINNKETPSKYLTRRLKVQRKTNEIPQILDPSNNCLVTKNEDILEVARRYYENLYQKRECNEDTHHELLKTFNKRIDQKILDEINQPIEGYEIRLGIEKIQEGKAPGKDGLLPTFYKNHINEILPIISKLYNHFWNTTIPKDFKQGILITIYKNKGDPNNLDNYRPITLLNVDYKIYSKIINNRILKFLNKIISPFQTGFVPRRLLHDNIITLNSTIEIIKREINTKEDMEPIITFYDFEKAFDSISHNAILRTLAHLKLPLKMVLTIMNLLNESETSVYINNSLSKSFTSKRGTKQGDPISPTIFALVVECMATTIINDRCINGVTKETIKILQFADDTATIAYNFMDHFLMNEWIKKFCQATSAKINQTKCSCITFKWNTRTLYTVIKSNERYLGFDFNNKGIKSKINTISDNIRAKLVTWNSTSSTYMGRLIMAKTYALSQLTFHTYINTTPQHNSIENNIVKFVFNTKSKNSLSLQRRQNNYINGGLNLWNLKTRELAQKAWLFERYLHQRVSNTPSSYIKLWEEELKNNNNNKTTTKQNQLQLHWQCKQAWTQLKTPQNKQTHYEHLPKLKKIYEDMMTTQSPEHNKFIPTPGQKEIMTKINSKHLPFKEIKKIINMKGRDLLWRYTLKALPKIYNMPCQQCGEDETSEHIFFNCKAHIKNTQEIFNYTLTKSGHTTHTWNVKILNHLQIALVANLIAIIFDKIWHKRNKLIHDEKEIIIHRQQVIRELIKTQRAAWDRTQAVINKTLRIKSKQRPEEQNKLDSLISLKLLQFSRQWNSPLHAIELPKHLKKYNNSLSTFYK", "length": 1047 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q551H6-1", "protein_name": "t-SNARE coiled-coil homology domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MATRDITSSYILSRTECKNRAKIINSAININIKKSGSGYKRLEEENYQDIDIDNNNNNNNINNNNINNNDNDNDTTNNIKNSNNNNDIQLNILDTEINIEQLNSLPPWILKLNDIDENIKKIISLIEKFKKYLKEDIDKILAEDIEMESRIDCERSIELLTMETIRLFHKTFDMIKYLNKSNNSSQGENKMKKNTQRMKSAKLKALLITFKHIQRSYLALLKKVSSLQRSLSSSFLYRSGEYDVNNDNEDYGENSSISNSHYLQHHHNNNHHHEDDHDHEEDHEEIMDELNEMATTLIERQRVSQLIKETSHLIQDVGSMCVKKDSIFDRIDYNLAEGEELEFNGTILICDGITNGYERPENEKRKKLLLIFAVLIIVILFIFILKYVIEI", "length": 391 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q551V5-1", "protein_name": "EGF-like domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKYLFRFFIFLFCITRINSQTGCFFRETGADYNIDSVFSVFYVDNLFNIFGMTFYMKTCTYVTCDPWRQTMICGNYNSTTFQLGPYQSQKVTLNKNGISIEYLSDKTPPNHPCPTITTTVKFICDKSVLSVPKSDYDYVGTCGVQIKLFAIDYCQTCSKCIASHGSCNSTSGWCTCDSYTMGLNCDQLKASISSVVAPTIDGGSVIISGDFSSIYSLGPSLVITIGSLVCSQVSFAASTTQISCTIGAGQGYQNLTISDGSGSTLQYKQFYYHYPCQEDCTPYGTCNDVIGKCTCNYKYSIGADCKTLNLQLTSVKPTLLDGGQAYLVGDFSNVTGLTLSVKIGIKECTDVNFNETTLQCTIGSGEGIKDIIITSDLLTYSKIGAYEYQYYTCPLGCLHGTCNKYNGLCVCNNGTYGDQCQYIECPLDCSTPNGVCDKDTGICDCDDKYSGEGCDFIKCPLDCSTPNGVCDGKTGICNCDEKHSGDSCQFLQCPLNCSNPNGICNRNTGICSCDSKYSGEGCDFIKCPTDCSTPNGTCDGKTGTCKCNNPYTGENCDEIAKCKQECSLKHGTCDSHTLDCICDTQTKGLSCEESRLLIESADPTSLDGGTTTITGYFGTTTSLLSIKIGDSQCTNIKVESDTKLKCDIGPGEGTHNVTVTDDDLSFTGVGMFQYVGQINKISKISGGAIAGIAAGCVVGVSVLGAGGYYQYRKNKKIELFMS", "length": 722 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q554Y8-1", "protein_name": "ADP-ribosylation factor-related", "gene_name": "arrB", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGMGFSFIEKKDFKRFLILGIDNSGKKKIMYRLKFNKDIPTRPEKGFFVETFERRFKYNNEDVCGQNMIRPLWPNYYTDETNGLIFVVDSSDQERIEEVRLEIKKLDENIKIFKNHPFLIFANKQDLKNSLSIEQLIDKLELNKLSLNRKWHIQSSNAITGDGLEFGLNWLFSSSHNFT", "length": 179 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q555E8-1", "protein_name": "Putative fatty acid elongase DDB_G0274669", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "METVQSIITEWTDPKSWEKLVQHSFKDSNWKELIDPVNYKFNFGVTPFSQFQIIPIVLVIYLVTIFSIKFLMKNRKPFSLKFISILHNAILCIWSLIMCVGVLYEIIKRVSNEGPLFTVCEDPNGGFDKGVTYYWSYIFYISKFYELLDTVIIVLKKKPLIFLHVYHHCKTVWWKKYITMIQILQFVCLGIAGVLHVYTINTIGCFTHYPAFAAAYSINFSFLFLFSKFFVKSYTPKNSNSNTNIKSKKID", "length": 251 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q555Q5-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MRSIRIKKINFHIKQGEEQLKQELNNYCEETSLKYISARIKKRHNDFTINAVKDAQGRTINKQELIEEEYVKYYSNLYDYKEDDAPSHYEMLENWTVTRDSTWDNLENEFTTQEILEVIKQLNPHKSPGPDGIPNLFYITHKEKLAPILASAFNDTLRNPHLISKNYKEGLIITIPKKGDPELIKNRRPITLANCIYKIHSKLINNRIIPILTKVINHNQKGFVPGRFIIDNIISMNELINYCNDKRINGIITLYDFEKAFDSISHGSILRSLQHINIPTNIINLIMNLLTKSEARIEINGRTTIPFEIKRGVKQGDPLSPTLFVLVIEALARKILQDDRITGLPLNNSDHREKFQSFADDSASMVPDSQQLELVLQHFNSFCKATSSKLNIDKSSSILIGNPDNTNQRIPISTNPERYLGYFFTGKGITRKIPEILNTIRSSLVLWKTTDSTIKTKTNILKAFALSKLTYYSYVENFKEEELNQINKLVEWFLSAPNTKMLVDFKITPKLSPTAKKDQEVNADYANHRFHKEYFEWNYKAIDYDLTRSFAYRNLMALILHNIWIWICNQIYSEDPLTDESLSYSSLLKKWHKLATLEYIKKAKDLKNLSAKDHNNFKDPKILLTSTIKLRKTTANYYCIPESSLPNIISFDQFI", "length": 655 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q556H5-1", "protein_name": "Cofilin-3", "gene_name": "cofD-2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTTPKPTIAKISPECQTHFQDIKFRNKYQGILLKVNEESNMVVDKTLVAEGEFSELAQSLPTDQCRIIIYRYKSGEGSKLFFIYWGPDSAPQQDKLIYGNAKVTLAITLKGIDHKISASNLKEISEQVFIDRITPKTA", "length": 138 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q556J5-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MWNHNLCHAINLDRQFDHINNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNKNNNNNSYDYSFSVHSSQQYSRHYPNSCNNEQTKPKDYYDHASRSQHDYHANGSNNGNNNNNNNNNNNNNNNNNNNSNNNNNNNNNNNNNNCDSNYNSNNNNSNNISIANIKYQQDQHYQHSDTYTSHQYNSFNDNNNNNNNNNNNNNNNNNINNDNDNNGYNQYDESEEDEEEQDDYDEFDIQDSASSYNDNCGVLNSNTYIYDYQSPQQPLYSNEYQNNNHQPQQTDSYNYNNTNNDNNSYNINNNNNNNSYNNNNNYNNSNNNNNIGNIDSNTNNNNYNYNYSNNGDVYNGYNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNMNNMNNMNNNIITSNREQFYSNNNHNNINQYQYQSQQQQTQQQQQQTQQQQQQTQQQQQTQQQQTQQQQQYLTQYYQQELYSQSYKCRPYYQNSFVISKC", "length": 480 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q556P1-1", "protein_name": "CWH43-like N-terminal domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MISSSLKPSVLLWILAILIPSTLITTYTLTVLLFHGIRRTVPYISDTIDFSPESCIGTFFISISAFLVFIVVFVKHFLLQNNINQNFNIDIILNENENEKKKNRAKMLNRISTFLGLICGVCIHGVSSFQYHNTGLVHSIFAASFFFTGFIYIFTQTYLDHKFSKLPKRILILRRVISLTTSVFIGYIILQFFIDNLAPILKIISALSIFFYLISFFYEFSKITINFQINTISQIEHQKEYNENSALLISQ", "length": 251 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q556R5-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MFNFERIDHGSGKGTGIAIENRDTRKGHISINFKDDDGRILSIKYNSFNSINILLINAPATISERNTFIINSKSLFKKYNSINHQIIAGDFNNNHDCNSFFGTELRKIIDQDMLLDTGIEENTPTFPRSMKRLDRIYCHPTLLNQNSKLVVHNTVFNKSDHFPITITIQTNRETTTTTTTTKLERLPWTLCKEILNNKHIHDGLSELISKNKDKIKSVEEWTKFKNNVIRDYLKKEQNKIKKEKNKRKYVIHKLLGNSDIIPKMRKELNEEISRILEEERKVKAWDIKLKLHLHQETPSKYLTSILKSRAKDKSIFQIKDKDNKTISDKENIAKRFVEFYQDQYEEKEDNEETHKKLLEKWEVDVDLIKKLEIDRPIRIHEVTKAIKTSSIHKSPGLDGINALFYKYHINSIARILTIAFNDLLTNKKEIPTKFKEGVITTIFKKGDELNISNRRPITLLNTDYKILSKILNSRLLDITSKIINKFQNGFVPNRFIQDNIQIMKEVIEISNKRKNNTLITFYDFNKAFDSISHKSITRTLEHIGIPPKFTAILLNLLKDTKNKIKINDFLVNGITIRTGTKQGDPISPTIFALVLEPLLIDIINDNTIKGFTLPNSKSLKLTAFADDIATFTNSTEELMKINTKIQKYCSATSSSLNKEKTVMIAIGDKPHDLPFQESTVPERYLGLNFTKTGLNSKYNTLIQEMKNNLIKWKSQAITMKAKMTILKTYVLSKLTYHQYMDNLNEEQIEEINNMTRWFLFSSVKNTYTEERKYKTMMKIDRAYADWKEGGIKLWDIELRHIAFKIWYMNRLLHNNYNNNNNTLQEWYMEQLSRKKPTLQPSTICADTGVYSESNFTKTIQR", "length": 861 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q556X2-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIAKTQIKCTTIYAPAKSNERHEWYKENLTEEILHSDIITGDFNVDCSVDNNLNKYIKTIFDEFEFTEIKNGITFPRNKSTIDRVFVSKKILHLNPIVTTKEIKLKSDHNMVIIELKIPEYEQQKKGERLWRQNLETLKMNSTSLKINKTIKYYNKKFEENTSKWYKLNICEQWLKLKDEIKKLSINIEIRESNKTKNKLKELAEKLETAKDSRAIFLKEEINNILKEQVRIKQANQTNTHINNKETPSKYLTRRLKVQRKTNEIPQILDPSNNCLVTKHEDILEVARRYYENLYQKRECNEDTHHELLKTFNKRIDQKILDEINQPIEGYEIRLGIEKIQEGKAPGKDGLLPTFYKNHINEILPIISKLYNHFWNTTIPKDFKQGILITIYKNKGDPNNLDNYRPITLLNVDYKIYSKIINNRILKFLNKIISPFQTGFVPRRLLHDNIITLNSTIEIIKREINTKEDMEPIITFYDFEKAFDSISHNAILRTLAHLKLPLKMVLTIMNLLNESETSVYINNSLSKSFTSKRGTKQGDPISPTIFALVVECMATTIINDRCINGVTKETIKILQFADDTATIAYNFMDHFLMNEWIKKFCQATSAKINQTKCSCITFKWNTRTLYTVIKSNERYLGFDFNNKGIKSKINTISDNIRAKLVTWNSTSSTYMGRLIMAKTYALSQLTFHTYINTTPQHNSIENNIVKFVFNTKSKNSLSLQRRQNNYINGGLNLWNLKTRELAQKAWLFERYLHQRVSNTPSSYIKLWEEELKNNNNNKTTTKQNQLQLHWQCKQAWTQLKTPQNKQTHYEHLPKLKKIYEDMMTTQSPEHNKFIPTPGQKEIMTKINSKHLPFKEIKKIINMKGRDLLWRYTLKALPKIYNMPCQQCGEDETSEHIFFNCKAHIKNTQEIFNYTLTKCGHTTHTWNVKILNHLQIALVANLIAIIFDKIWHKRNKLIHDEKEIIIHRQQVIRELIKTQRAAWDRTQAVINKTLRIKSKQRPEEQNKLDSLISLKLLQFSRQWNSPLHAIELPKHLKKYNNSLSTFYK", "length": 1047 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q557C9-1", "protein_name": "Homeobox protein 5", "gene_name": "hbx5-2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "METIVNNQNNGQQNTVPTQSFSSSVYMNYDFFDSQQLQQPQHQPQHYQQQDSFVSPNLDNNNPQIHVQSNNYNQNGFVGYNNSNNNNNNNQHMNNQYSNSFHNNNSSGFMAFQNNSSNFNNQNNNNSNNNNNNNNINSYDYNNSNNNNYNNNNNTHSNNSNNNNNNNNSNYWNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSNNNNNNNNNNNHHHHHHQQQSQPTSPYNNPIQHNPNDMKFNGQHNPFNGNQMVMDNNNNNNNNNNSNVFNSNSNSNVFNSNSGSFLQINNNNGSFSSYNNNNNNNNNNNSNSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSNNNNNNQFSQSYDSTLGNNRFSSMMGQPIQQQQSPPQQQQQQSFIQSSPQAIPASNCNGNGSTSSSTSPLSPTLIGSAPGTPTSMLATTLFGFNLSSSPTSSPSSPVKKGKSQSALALSSSGGSGGSSGRKKPQKHDSMSSITNTNLKSTQASTLKESKRSNSSPNLKKQMQLQQLQQQQKLNENGTLIPPLPFASISENITNNNNNNNNNNNNNNNNNNNNNITNNPLSGSMEFPNSNNINQSSDSINGEFNIGQPESPKMYNSSPSPPPNATSTTKGGKKSKKSLHISTTQQSPSLNGSTGGSMLTPTMSGLSLSGGGSGGGFSPLISPTGTTSNKDLQSSPSPSPLLKSMSMGKLDLQDSIDSMSSPLSPNSSLSSSNGLLPPPPNSNNMNSSGGIPTPSTPTSPPPLTHHINIFSNLEFVKQLKDHLLPNDFKPEEHALERNLLRFQQFVKTLAEPLQRDVVTSMFELSVDAQLQYGSNLDNDNLSALMLFRRKILNFNLFRMMMLNDPNSFIPLPSPFPIQTTTISSNGTIVNPTNVNNNNINNNNNNNNNNNNNNNNNNNNNNNNNNNNTTTTTTTTTSANTVQSGTTSNSNLVFQQTSNSNTLSPSQQQQQQTQQQQSINGSSTGSLSDAQYQDLGIHLDTSSANSGCGINVSIGSSIGGGGGGSSLNGSNLNGSSSISGSISGGSSNGGGQFIMSPQFSLDGAYQQQQPSSYNINNEMELAEKDEDEIFNNNNKDNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSSSINSNINNVNNCNINNNSNSNNGSINSPRPSTPTTLNSSGKRSKKIYRGDSFGAGNDISTGLMASSDQIIPPPQQQQHQQLVNNNNNNMNNSENNILLADSNKGLSVSLGSLPTNTPSSMEIEQQQQQQQQQQQQQQQQHLNQQQILHQQLHHHLSSSLGGAQFTNIQQQQQQQSGNIFYNSPYNSSQVYMNPYGTSITNTSLAGPSTTSSAMQHMITNMTSSNIIVNNQNNNNNDQNNNNNNNNNNNSTTNSNVNNNNNTTNTPSSPPQPNNCTPTQTSIITSNGVVVPSLQMRGTITNPPPVLPTPDTLVLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQETPHTPTSNSISSPRSSPVHQQSPSNTNTTTTSTTTIRHSAVTQLSFAGLHNQQVSPISPRSPRSPHGTSGDYNDGSQSPSSRRKNRFTDFQIKRMNDCFENLDKNNNGKFTSEEICQIATELGLTDQQVRVFFQNKRARSRPSPRGQPTNPLTSSTNNGNNSNLALQHLQQQHLQQVQQQQQQLLQLQQQQQQQQQQLHQQSANTTPQLNSMNPNSINYNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNIINNNITTINE", "length": 1723 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q557D0-1", "protein_name": "RING-type domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTGSNNLNSLNNNNNNKISLQETIQDIIKCSICLNSPKNPRFCPRCSALFCLECIDRWIISNPTCPACRDTLTSDNLNSNLIVSNILNELVKSEQEEYTSSDICNYHGYERLYYCSTCQEPICSDCALFKHKDHKIEKLSINFNKNLEILKIEEEALKKRQEELIELNSFLELDAETLLKNKSQIEKEISKVVITMKARLKYDFERRYNTILESQEKINNELTHLDFIYNDLLNHYKKSPSSFVLTSQQFIGVLQSVHKNSIMDIYTPINTDLTSELIPPFENRLLKFENFTTGDCLFSSRIAFYGMTWEIKCGIEEDNCFLNLKVLECNSDGKYFYMFTIVNQKTNVNKLIEFDLPFQAGETFYIPNFSSKQTLIDEGFILPENDILLLQFSFRPQNYFCYSNDLKRYIDILEYRHRGYFGEEDEDDGTIETTVTKLPNDKSTILGSDNYNDNYNDDGIGDLDEDEEEEEDDEDDDDNLDDHLQYDNDDDEDEEEDDEEQNEEDNDEEGTNIPTSEYEDLDTSSASVISNINRRDRFKNNNINNNNQFVNSNNNNNKYNTTNSNNSIVGSSRYINNNNNNNNNNNNNNNNNNNNNNNNNNNNNYILNRSYSTNKIYNFYQDEEEEEEDDDSNIDDQDEDEEEEDSEEESSLSSSDLQDLDSSGDQSSLEFSFSKYTNNYYSNNNNNYNSGGGGGVGGAGDNNKIECIRRDFNNLLKRINFTNSQLTNLKPGVPKDGDLLNDDENDKKCNIPLNEDEEEDEDEEDDVNKNKTTSTTTTTTTATTTNEVVTINPNTISNNSQDEEEVKSDIVKLLENGIANMLNNSNSSNRSSNNLKQQQQQQQQLQKDDQKQKDEQQNKSNTGCDIDQLNILSKLSIKESCDSIKNNDNDSLGNSTNNNNNNNLNNNNNNNNNNNNNNNNNNNNNNSNNNNLQSFLQSNENTENETDFNDNNTNPETNTETENEYLTSSNMNLDGGESEFDSNKSYEGSSTDENFNSDEDYQDEDNFNQDATGSESANNDDYLDDNEREGSDSIENYDEDIEKVLTSHNIITTPSIPPSQQPQPQLQTQPQTQPQSQPQSQPQLQPQSQPQPQTQPQLQPQLQPQLQPQLQPQLQPQLQPQLQPQTQPQQQKKYDDLSENQIQTENRNKKIKEEINNKTNNDNNNELGKSSKSNTSSSSSSSSSSSSSYSESESSESDSNNEYDNEDEDDIVNQVSNFNFNFNDASNFKNFSFRPKFPSDENDNDDNDDDYEINIDLKNIQKISPILRAIENGESNINHYQSPVSLSSSSSVSSFSGSGNSVPITATTTTTTTTTTTTTTTTDDDSGINMPISPLSASPPSPPPQNEPQINNETNDNDVKLPQI", "length": 1364 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q559A9-1", "protein_name": "Probable polyketide synthase 13", "gene_name": "pks13", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MENFKYRNNENDVAIIGIGFRLPGCKNFTPNELWNNLKNGFNGVVELSNRWSDNFYTMGKVSSAYAGLLPFDELKSFDPLFFGINPTEVPTIDPQQRILLKCTWEAFEDAGIDPIKIRGSNTSVFIGTSTNDYQRIIREKDQTITNAFGTSLHATSNRISYCFDFRGPSMTLDTACSSSLNCVKLGYQSIRDGTSNLSIAGGVNLIIDPYFTASISDLNILSKTGSCKTFDASADGFARAEGSGIIVMKNLKQAMIDGDKIYCVIKGASSNVDGGGLQDKSNFYAPSSLSQCNNIKMALKSTNGTVEPKDISYFECHGTGTPTGDPIETRGISMVFNDESRSKENPLLIGSIKSNIGHLEAGSGIASLIKCCLMFKNKCFAPNINFKVPNPKIKFEEWNLKVVTEPIQFTKSNTCIGLSNFGVTGSNCCLILSQFNNNNNDNQIVGNNNNIKSNKEYLIPFSSNSVKSLENYQQLLIKNGENEFKFLEFIKHQIFTKPTSLYQRSVVIASSWDQFNNAKIMKTSNSKSSNISIERNNPITVFVFCGQGSQYDRMGLELYNNDFIFKESMDLLDNKLSKYYGYSVLEKLRNCDSKSIQHPMIAQPVMCMFNISLFELYKHWGIEVSFIIGHSLGEIPAAYCSGMINIDTLCYLIYHRSIAQTKTHTNGRMLSINISADEYFSQYSKQYPDIEIACFNSPTSIVIAGNEQKLNEISEILKEKGIFSAMLASLSSFHTSSQNKVKEDIVNKQFDSKQSEIPIFSTVTTNLFDSVTSPFNSSYVFNNIVSPVKFSQTISNLYKHIESNQLGNDIVFIELAPHPTLQFYLKQMIPKPTNDDNSIEFKVSVYSALNKKNNDIEEIQRTISQLYCDNGYNVNFKCQFQHDDTHGSINSNINQLSNISLPHYQWDDEKYWKEDPSISKLIVNGPQTDNLGYLNENSPNSKSYETFIDIKRPPFQYLKGHMVKGKYYFPGCGYIDNLLKIYKSQDLTINQMGFKSPLIFIEGVNQALQTNIFKKSTSNTTTNNNDEFRVEYHFNDQKTNRWILSSFGDFQLSNHSSNSDNLEKINIKQLIQNQCNLTKLSRDELYSHIKSKTGLTYNGVFQGVNKCYLGENCSLSEVSLELKREPSSFFNTAVLDTCLHGMLCLLEEQSQLVFDRIEGFKYHSSNVPTSEEEMKIHSNIYVYSTINPSRIGDSYSASIVIMMEDGTVLIEIENAVCTSLTPIKESISVKYPTNQLFSMYLQSKDSPIPSPLNFKSLYNQNQQQLKIDKQFTDWMQKCEKFISNQFFKNIEKRNPEINLEILNSKTIIELKSKYCQNLKNERLFQFVFETIKQLGVNAYDDDDDLTIDSSEDRKSIYEILIKSTKVIPKLLFPLEDEDLTIDSPQSLFENGLLDRFYNNPNLMTNQCQLIAQIIKESLKPLLNKKMVFRILEMGGGTCSLSVVVLNLINQLLLENPSFEIDIEYTWSDISPSFISAAKEKLSHIDKRINILYRSIDIEQPFIEKQDLSPSYYDFVIMSNVLHVVKKLSPSLDEIHKILTPNGHLLFVEIPYKELISDSIFGAFNQWWAFEDTDIRKDRCSIPPNQWIQVLSNHNYKDTIVSDNKECTWCCFVIHSQKPSLLELSKKIECNQYDNIIVFGNENSQDNFTKSIKLSYNNNIIKWVSNIVEIKKFIKLNIITNNSIIYFTKGIEELTIDNFKLINFQYIQINQLLLKYESKCKNVLVTRDCDGSNYLASSLIGAARYFDEYRQLELFTLDFDNDTIQSCDECSSSSCSNLIKLIEPLIDPKINIQREFLIRNNRVYFERAKLETNLKKSFKSESFENSNKLISTLNFNLDYQLQSKPFKQLLQNEIEVEIKATGINYRDYLVFTGSLPIEKTNHNGISNQPEFGVDFSGIVTKVGGGGGNGEFKVGDRVYGIGHNTTSSHITIDSRYASLIPNSLDYIEASSITSSYILSLYGIFDIGNLDIQDNESILIHSGTGGIGLSALNSLRWKGHKSHLFVTVSSKEKEQYLRDNYGSFITGIYSNKDKNYPKLIKEKLNQLGSNKQGVDLILSSLPNGDDNLNFKCLAKNGRIIDLSNNIDLFNISKSKIKKLLNTINDGFESGELQVIPIIEFSNSNIRDAIEFINERQHIGKIVISHDDSNLLIDLINKHSNQPNYSILKSDYQISQSNLGKNILITGQSGIVLEILKWIIKFSNSIENVIILSKSLMKWELELLIGKTMKKANNKIKFHFKSVDVSDSIQVENSINQILNDNPNIVNIDSIFHFAFTQITKKVEEIDMESLNVSHNAKTIGAINLHNQSINRNWRLNNFVMASSATSIIGSTDQCSYVCANTVLDSLSKYRKSIGLPSICTNYGAIESAGFVSKNESVAAMFNGIGIISISTDLILGTLDLQIQNQQSSTNLMLSDFNFLNFVNNNLQLSLISKFDFQTNLAKNQVNEKLQNQTQNQNLQIQSPSSTTDCQTIIKDSFLHKISEVLSIDISKLNLDLKLLDYGADSLAIVQIKNWIDMEVSPNLIVIQQLQTFTITSSIQYTINSFLKKKVQSQE", "length": 2551 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q559I8-1", "protein_name": "Uncharacterized protein DDB_G0272530", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKIKLILVLIVFLTIVNVNNSIDLCLSNPKKALVNQACKYSTDCEYPLFCGSGNGYGKNATCSKNIETGGSCESNNQCTPCNVCFNAKCKVKLYLGDACDENKSYCSSSVCIKGKCSIQGDVCTANNQCKFNNYCKSGKCVPLEKEGSSCDKDSSCSLTNACVGGKCVTKYQKPLGAVCNSSNECQVFSGHVCGANGKCSVYNQLLSKCKENSDCGPNGMCMCKSETENVCVDLSVGALKNDKCPSLLSSFSSCMTRERCTENTPTGCPKCYPIFMCYQYSCFYMNQFIRSTQNYYKSFCS", "length": 301 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q559Z2-1", "protein_name": "E2F/DP family winged-helix DNA-binding domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNISLLLNNRNRNRNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSNNGNANESASLNNGSEEIRSNPSSNFSSPIQSSLSSSSSSLSSNQATTPKKRSHAHKNSLKCQSPQMSPQMSPQMSPQMSPPLQYFPQHQMQHLSQYQLDHLQQQQQLIQQEQQEKQQQQQQHQHQQQQQEQQKQQQKQQQRLSPQPRSSQPRSSPPRSSPQRSPQLNQQEGHINSVQTYSGNNINDKNQNNTNNNNNNMSNNNNFHDDNNCNVNYNNIRNNSNNNNNNNTNNNNNNNNNNNNNNNNNNNNINNNNNNNNNSNNNNWNNNYCNNSFADETNKNNTYGMEYINISEENQYNNNNNNNNSNNNNNYNNYNNYNNNNNNNNNNNNSNNSNSNNNNNNNNNNNNNNNNNRNNIINSNINNSNNNNYNDNGYNNNSNINSNDSYNNNNNNNNNFNNNNFNNNNNNNNNNNNNNNNNNNNNKNNNNSNSYNNNNNNYNNNNNNFHNNNNNSAHNNNNNNYNNNNNNNYYNSNNNNNFHNNNNNNNNNGNNFNNNNNNNGNNGNMFTNVNSIDNVNRNNYNNYNGNNNYNGNNSNNNNNSNNEVSQITTTSLPVKKTKVFKAPREKKFKRGPDQDIREIKPATALLKQYFIGNSITEFNAERVGSILKINHEKLKDILDIMECASLVINNHSNNYVWLGLDNPGFLKLVFNVFHCSSNLVTKEPEFACLKCKENAYRCPTSVDLPKDTRLGSTVCQFMKLLLSKRIRTNPVNDFLTIYQVCFNFNFCSEGRCPEEDFKYLRNTAKVKRCYDVANVFNGLNILEKVGKSKIHSYQWCGDFTIQDCENGCPFGHPLLTPGTAYTTNPSPNPFNQFSNAYISSSAQSSLSNSPFIQGGFHGNNNNSNNNNINGNNINGNNNYGYNNNNNYNNYNSNNSNGFNNGNSFFQQQQPLVNSGVSMVRNNNYSYSP", "length": 964 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55A39-1", "protein_name": "Transcription initiation factor TFIID subunit", "gene_name": "taf9", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSSNETLPNSEQENNSKTDTKNDNKNIGDENKIIDTDKDMKDNDTINGKENGNININSNNNNNNNIDTDKEMKETSSIEEDDNNNNKNQNNNNNNNIKEENDNLTELKNNNNKENKENKEETIKEDKEKENNKEPVKNKEETNNINNNNNKNNNSDNINNNNNNNSKETLNKISSMSKVSLTSESSEINGQVNTGVVNNNTNIDITQTNLDEPRDSRVIKSILKTMGIQAHEPRVVNQLLEFMYKYVFEVLQDAMIYGEHSGKTDIDVSDVRLSIQSRVNYQISTPPPRELLLSIAEEKNKTPLPPIPNRYGVFLPPDEYCLTNPNYQANPTKPVFQPVQPLVGNTSRGNYNKKQSDKQVSIKFNSMSNNSTTTTTTTPPTIGSQNGTTIVSPPNLGSLGTTTTTTTTTITPPPPILPLSSNIKPPTLSIPSSITSPPTVTTKNTSTPIIGLGSTTVAPPKTSSSSSTIAPPVLSLPTSITSPPTVTASSTTTTTTAPTTTSPTIPSLSSPTTAATTITVKKEDVKMDDFDDFDGQMKDDITPSSTPQQPSQPTESETTTTATATTTPAVTTTTIPPTTTSTTPPTTATTSTTPPPSTTTTSTPPTTSTTPPPQIKEEK", "length": 619 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55B17-1", "protein_name": "Amine oxidase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MYKKILLIFALFILVNINFASSEFKKNETESANLKSLYASYLMKNNNNTKYNNNDNSNNTNIYNDSVTKNKSKNKNELTVGIIGGGIAGLYAGMLFIKSMIFDDLGIDYTILEANKERVGGRVYTHKFDDHKYSYTDLGAMRIPLTPLMDRIVSNQNYSLFSKLAKGGYQIPTVPFLISVNNEISYYNGIRVLKGSPVLNPSDPFNYSDSNNGGPGKGIPDEYANRTVDSLILPVFYQFINNLTVDFYNGFKQMLKYDSYSARDYLKTFHNYPNSVIEYIENLSTISGRLDQTSITELLMSVFDFSGEKFVCVEGGTGLIVKSMSQIIKKKVEMGSFVTKISKSFDKKNNEIDGLNVEVVRDSNFGGSDTEILKFKHVISTTTLPALQRIDTSDLKLPLKLKVAIRSLKYTGAIKLAINFKYRWWEDSEFMSGKPIRGGSSNTDLLLRQVVYPSYGINNGTKGVSGVLLASYSGGLESIRISSMIGKKDKERKLLNIVLRDLAEIHNVDLKKLKNLYKDHFFQSWDNDEFSSGAFALFSTSQYTELFPSTGQSHVDGRFHLSGELTSVHHAWMIGGLNSAYRSVDLILKNEGFEDLRIKLRNNWGTIEQAEYPSLDWYKYDSDINHYKLY", "length": 630 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55BT6-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKLLYIVVFLLFAIKLCCSEYCGETYCVENRNCYSFIGCRNSTCLYETIDLDDEVDCTVDTCSDRYGVKNTPNNSLCPPENLCDMFLCDTQSGCVAIPKVNCPAPNPCQIPLGCNRETGICEYDEIDCHDDNECTNDYCDPILGECVHFSNDTICSNKASNFSTCVLSGVCGEFGCKYVEDNCNDGNPCTDDYCDFKNGCVSQKNDWNCDSLSACSEGICTDNGCVQQEVDCDDDNPCSEDFCHPLFGCGSILNDTICTNGNKCVNSTCTEDGCSLPVPIVCQDGNPCSDDTCNPSTGCQFTLNNSNCNDGKKCTIDQCGLNGCTHTNITCPPKRVVDIILIGLICRNHYCDQSTGNCVPDMNSVSLLCI", "length": 370 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55C69-1", "protein_name": "Chromo domain-containing protein", "gene_name": "hcpC", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGKTNKKKIEEESEEEEAGDVFEVEKILDKRVQHGRIQYNIRWKGFSADYDTWEDEANVVGCPELVREFESSRIKEKKKNRKRKNVIIDEDPTEEISSSLSSILSSPQPQPPPPLQLTNHSPASSELAITTNTFLISNCTSTSNKTKISIENEEIIKNDHARYGVPYVEGIGFENGDCVDEIVGCKPFGENNLLYFFIRWRGKEKLSWVSNESIKQKEPLQLIEFYESRLKFGYKGEEN", "length": 239 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55CH5-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIAKTQIKCTTIYAPAKSNERHEWYKENLTEEILHSDIITGDFNVDCSVDNNLNKYIKTIFDEFEFTEIKNGITFPRNKSTIDRVFVSKKILHLNPIVTTKEIKLKSDHNMVIIELKIPEYEQQKKGERLWRQNLETLKMNSTSLKINKTIKYYNKKFEENTSKWYKLNICEQWLKLKDEIKKLSINIEIRESNKTKNKLKELAEKLETAKDSRAIFLKEEINNILKEQVRIKQANQTNTHINNKETPSKYLTRRLKVQRKTNEIPQILDPSNNCLVTKHEDILEVARRYYENLYQKRECNEDTHHELLKTFNKRIDQKILDEINQPIEGYEIRLGIEKIQEGKAPGKDGLLPTFYKNHINEILPIISKLYNHFWNTTIPKDFKQGILITIYKNKGDPNNLDNYRPITLLNVDYKIYSKIINNRILKFLNKIISPFQTGFVPRRLLHDNIITLNSTIEIIKREINTKEDMEPIITFYDFEKAFDSISHNAILRTLAHLKLPLKMVLTIMNLLNESETSVYINNSLSKSFTSKRGTKQGDPISPTIFALVVECMATTIINDRCINGVTKETIKILQFADDTATIAYNFMDHFLMNEWIKKFCQATSAKINQTKCSCITFKWNTRTLYTVIKSNERYLGFDFNNKGIKSKINTISDNIRAKLVTWNSTSSTYMGRLIMAKTYALSQLTFHTYINTTPQHNSIENNIVKFVFNTKSKNSLSLQRRQNNYINGGLNLWNLKTRELAQKAWLFERYLHQRVSNTPSSYIKLWEEELKNNNNNKTTTKQNQLQLHWQCKQAWTQLKTPQNKQTHYEHLPKLKKIYEDMMTTQSPEHNKFIPTPGQKEIMTKINSKHLPFKEIKKIINMKGRDLLWRYTLKALPKIYNMPCQQCGEDETSEHIFFNCKAHIKNTQEIFNYTLTKCGHTTHTWNVKILNHLQIALVANLIAIIFDKIWHKRNKLIHDEKEIIIHRQQVIRELIKTQRAAWDRTQAVINKTLRIKSKQRPEEQNKLDSLISLKLLQFSRQWNSPLHAIELPKHLKKNNNSLSTFYK", "length": 1047 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55CH7-1", "protein_name": "SsDNA-binding transcriptional regulator", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIFKITRTKRRWTKNQKKILVMKVVEKKVVVKKSKTPNTSPSSSSSSSSSSSSSSSSSSTNDKSFNLSDKRKISYSNFKGLERIDIREFFEDKSGELKPSSKGISLTREQLVVILENGDTIKDWIKESK", "length": 129 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55CJ7-1", "protein_name": "diaminopimelate epimerase", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEPSIDNKPSFRINFTKMHGAGNDFVVFEKNKVERLNGDKSTVTFEEIVGFTTKIAHRKLGIGFDQLIVIDDNPIDKNAAYGMDVINCDGNIEVMCGNGVRCFSKYIVDNKVLSKNLKEQLNFDGDDDIEQIIETKSGIVKTYPLLKHHLNNKDNDVIMVKVNMGTPKVSRFINEIDRHIPKVLTNQSPIESYMYTIDIGLPYCSKLECVYVTVGGNQCVVFIDRNIELGYLDSSYGDHTKFSTIDFKEISDIIQSNVNGFDDIPNVEFVIQSPQDKLENKVISRVVERGNGETLACGTGACGVAISSILKGYCNENTEITVEMPGGKLLIQWNPNNEIFKTGPATSVFKSQILI", "length": 355 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55CV8-1", "protein_name": "Lipocalin/cytosolic fatty-acid binding domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MELLVGGTILGALTYAYSSLKRTIPEGAHACSPFYPEKYVGKWYEIARLDFYYERDMNNVSAEYTLNKDGTISVINSGYNYVEKKRESVNGKALFVHGSDEAMLKVSFFGPFYAGYNVIAIDPDYKYALVAGRSLDYLWILSRETSIPDHIKKQYLELAESIGYNTSKLIWTEHDNINNKKD", "length": 182 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55D49-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIKIMTWNCQGCSTIKSMNQTKNTINLIKPDISILTETNLKKDQNLAQIKNHYSTGGKGKEARGKGVMAINHLEQIEIKNLEEKEGRILKFTAILNNMEINIICIYAPASYDRRKGWFSNNISLEDLEQADIVTGDFNINKYAKIKFKDGSSDKRKFTENETIEFLMMEVGLTEILPNSTTKTTFKDKLIDRTFLSTKMHQLNHSYKIIDKINKSDHNIVVMDFKIPNFTKIYKSPLWKMNSIIIKEDKTIKKIEKIIDHYQETKRKNINITEYWIKFKKKIKKQCITTEKKRILERKKTLSNLANEHTKTKNKYEKETISNEITILQEEERIDRMIKSSINYINNKEIASNLLTSILKKRDSSSQIHRIKNPSNGEIETEQKEITDCFRKYYETLFKEKECDQETHTELLSTWNPPIDKKKLTEMEDRIEEYEVKLAIEKIAEGKSPGEDGITSSFYKIHQHKLIPILTELFNFFLNNEIPTEFKNGILTSIYKGKGDVLEISNRRPITLLNVDYKIYSKIINNRILKILPNIISKYQNGFIPGRLLHNNIIALDLAMEKSDRNTIITFYDFEKAFDSISHKALIRTLNHLKFPRKITNTILSMLTNTNIRVMVNGQLSESFRAGRGTKQGDPISPTLFAIVCECLSTSIRKDNTIIGIKLNQNNSMKIGQYADDTVTLASNIDDADKMDMKVIKFCQATAAKINDNKCVCITKNPKIKTKYKTIGAKEEERYLGFFFNRKGVISKVDDTVNKLENLTKCYSSVSSTLKGRITILKSYLLSQLTFQLYINEINDIKKLENVNANMLFKGDRWAISKERSRRDYEIGGLELWNMATRSNAQKAWIYEQYLREKDDQNCPPHMEVWKSEKENSLSRIHIKCWKAWKLLHHPRERITLKLNQVKPKYENKQKLKVIYRNMMDIKYKGWNKHQPTTGQKLIQKNINHPILPFREARSITTIKGRDLAWRYLLKALPKHHGENCHSCKEEESSMHIFFECKSIKQNIDSIYQKVCKDSNNTYHGPWSEKVLGKLLTPFSSNLIGAIMESIWYRRNQIKFNDNTTIITENQIIHKIKKARDAEWDRTRKIVEKQLRQELRCTDNRESINRTASIKRRLEKFSHNWNSKLMTINIPEHFIPYCSYNTNYS", "length": 1144 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55D57-1", "protein_name": "J domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIQVKNKIKIISILITLFILTINQVVECKSSLYYSILNDYEKGIDYYKILNVTKDSTYSEIKKSFRKLSLKHHPDRNVEKSSHSLYILLNQAHSVLTTDETRKEYDELLVNGIPWHENYYGKYAYRYTGISHDLRHVLLGLIIVITIGKFVYQYNKHHSMIKRAKQTDQYKKRLAQLDGDEDEIQLVIQGADKPTISSLFIIQLFFIFPFKILKSIYTFIFINKFKFIQKTDEEKEEEYRLKMGYTKEDWEYHKKKSIERMEKLKQSGKYKKYLRSKNK", "length": 279 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55E25-1", "protein_name": "DRBM domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSNKSHTSEKVQLNEFLQKKKQPIPIYHTESKGSEHNKDFKSIVVVNGKQIESDWKKSKKESEKDCAKNILEFIETLDGYPIYFTPFSKDPPQNNKKIYDEKLQAVYNSVSSGIEGLNNNSFFTKIENNNNNSSSNNNNNLDHNHSNDSSHTSTDNNDNNSNNHNNNNNNQINIDLTMENVNISQSKTITNEGTLNNDNDNNNNSIQQQQHQPQPQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQCFDKDKTNLKKKKKIPFSYNTDLIEHIDLFKRQDFPQTYPSRTTYTDTGHTQQLQKQVFLLTEKIGLMELFYKKQIRVILKSHHNLETELSALKSFVEDCSVTPIEGLELYSIPVPLNPNAKPSAGTTPVLSKSETQNEIIQPTKPPTKPPASCLIKKKIPNVNMKATNKTTTTTSTSTSNSSTTIKTTDSFKNTTNNQHPNTLKPMVSKINQQTSDFIFPLPKPIIRRNPIGNGNLEKKIEKKNSKPNTIVLGVDTQSQSKTKITPSPTTPPPETTPTTPTTTATPTTPTTPTTPTTTATPPPTTTATPPPTTTATPPPTATTPPPTTATTTPPPPPIIATTKTTATATATTIPIDLNEIQIPIRSPQDLTVNQSMISTAMMIASAAQRNPKLTMKLKRKLEESPTLMSKLQKIQFEKEEEILCSQDLHSPIMSPQSPTHQPKTLEPLSPTKKSTQKSPPPTSPSPIVTRARASSNLLPIQNLISKK", "length": 733 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55E47-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIAKTQIKCTTIYAPAKSNERHEWYKENLTEEILHSDIITGDFNVDCSVDNNLNKYIKTIFDEFEFTEIKNGITFPRNKSTIDRVFVSKKILHLNPIVTTKEIKLKSDHNMVIIELKIPEYEQQKKGERLWRQNLETLKMNSTSLKINKTIKYYNKKFEENTSKWYKLNICEQWLKLKDEIKKLSINIEIRESNKTKNKLKELAEKLETAKDSRAIFLKEEINNILKEQVRIKQANQTNTHINNKETPSKYLTRRLKVQRKTNEIPQILDPSNNCLVTKNEDILEVARRYYENLYQKRECNEDTHHELLKTFNKRIDQKILDEINQPIEEYEIRLGIEKIQEGKAPGKDGLLPTFYKNHINEILPIISKLYNHFWNTTIPKDFKQGILITIYKNKGDPNNLDNYRPITLLNVDYKIYSKIINNRILKFLNKIISPFQTGFVPRRLLHDNIITLNSTIEIIKREINTKEDMEPIITFYDFEKAFDSISHNAILRTLAHLKLPLKMVLTIMNLLNESETSVYINNSLSKSFTSKRGTKQGDPISPTIFALVVECMATTIINDRCINGVTKETIKILQFADDTATIAYNFMDHFLMNEWIKKFCQATSAKINQTKCSCITFKWNTRTLYTVIKSNERYLGFDFNNKGIKSKINTISDNIRAKLVTWNSTSSTYMGRLIMAKTYALSQLTFHTYINTTPQHNSIENNIVKFVFNTKSKNSLSLQRRQNNYINGGLNLWNLKTRELAQKAWLFERYLHQRVSNTPSSYIKLWEEELKNNNNNKTTTKQNQLQLHWQCKQAWTQLKTPQNKQTHYEHLPKLKKIYEDMMTTQSPEHNKFIPTPGQKEIMTKINSKHLPFKEIKKIINMKGRDLLWRYTLKALPKIYNMPCQQCGEDETSEHIFFNCKAHIKNTQEIFNYTLTKSGHTTHTWNVKILNHLQIALVANLIAIIFDKIWHKRNKLIHDEKEIIIHRQQVIRELIKTQRAAWDRTQAVINKTLRIKSKQRPEEQNKLDSLISLKLLQFSRQWNSPLHAIELPKHLKKYNNSLSTFYK", "length": 1047 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55E48-1", "protein_name": "thioredoxin-dependent peroxiredoxin", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTKLKVGNIAPDFEAKNYLGQIVTLKEFKEKSQPIVLYFYPKDNSPECQKSCEFRDKYQKSIEAGAEVIGVSSDGEDSHKSFVSKYSLPFTLLTDKHSKLAKLYGVNGILLPGRKTFIIDKHGFMAVFMMVYSVQLLMSMNL", "length": 142 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55ED8-1", "protein_name": "Decapping nuclease", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKQTLNVIGLINFIKKQRSFNKSPITITKPLEITRFSYEGNQLFPAKLKKFKNPTIDSDLLVGFQGPDSIESDSQTPLSLVLNKLIETKHDVSKSNFISFRNSFRKLFESMYDSEKWNIQVQRINSTIHLGMDNPTQDFHQLKNFHLKSMYSGNYFEKISTIDNNNNPNDNKHKYCSIIQSKLFNNNFILACEIDCWKKSIQNNNNNQNNNNNENNNNDDDDENYNIDDYVELKTSRDIEDSKANYQFRSKKLIRIWFQAYIAGVSKIFLGIRNDDFFLKKCLNFNTHDLPNQAINWNKDEMLIYGNEILEFIKNNTCSGKSYTLSFNYPIISLVESDSINIINDQYLQYYLNIPKNFENNYNQNNNQNNNNNNNNENNSDDTKNNNIQNNNENNNIQNNNENNNQNNNEKNQKRNFGEEKEIKGDENEERLSKKQKKLE", "length": 440 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55EZ2-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIAKTQIKCTTIYAPAKSNERHEWYKENLTEEILHSDIITGDFNVDCSVDNNLNKYIKTIFDEFEFTEIKNGITFPRNKSTIDRVFVSKKILHLNPIVTTKEIKLKSDHNMVIIELKIPEYEQQKKGERLWRQNLETLKMNSTSLKINKTIKYYNKKFEENTSKWYKLNICEQWLKLKDEIKKLSINIEIRESNKTKNKLKELAEKLETAKDSRAIFLKEEINNILKEQVRIKQANQTNTHINNKETPSKYLTRRLKVQRKTNEIPQILDPSNNCLVTKNEDILEVARRYYENLYQKRECNEDTHHELLKTFNKRIDQKILDEINQPIEEYEIRLGIEKIQEGKAPGKDGLLPTFYKNHINEILPIISKLYNHFWNTTIPKDFKQGILITIYKNKGDPNNLDNYRPITLLNVDYKIYSKIINNRILKFLNKIISPFQTGFVPRRLLHDNIITLNSTIEIIKREINTKEDMEPIITFYDFEKAFDSISHNAILRTLAHLKLPLKMVLTIMNLLNESETSVYINNSLSKSFTSKRGTKQGDPISPTIFALVVECMATTIINDRCINGVTKETIKILQFADDTATIAYNFMDHFLMNEWIKKFCQATSAKINQTKCSCITFKWNTRTLYTVIKSNERYLGFDFNNKGIKSKINTISDNIRAKLVTWNSTSSTYMGRLIMAKTYALSQLTFHTYINTTPQHNSIENNIVKFVFNTKSKNSLSLQRRQNNYINGGLNLWNLKTRELAQKAWLFERYLHQRVSNTPSSYIKLWEEELKNNNNNKTTTKQNQLQLHWQCKQAWTQLKTPQNKQTHYEHLPKLKKIYEDMMTTQSPEHNKFIPTPGQKEIMTKINSKHLPFKEIKKIINMKGRDLLWRYTLKALPKIYNMPCQQCGEDETSEHIFFNCKAHIKNTQEIFNYTLTKCGHTTHTWNVKILNHLQIALVANLIAIIFDKIWHKRNKLIHDEKEIIIHRQQVIRELIKTQRAAWDRTQAVINKTLRIKSKQRPEEQNKLDSLISLKLLQFSRQWNSPLHAIELPKHLKKYNNSLSTFYK", "length": 1047 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55F94-1", "protein_name": "Dynamin-like protein A", "gene_name": "dlpA", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSVFKKKDKSDDKKKKHDEETPQGTFQPASQSTSNTNLNSLASSVNNGASVGSTNGSTPNNSNGSTPTYNHNNSAEELEKQKKEEDEKRKKSELEAAAAVVAKKKEDEEKQRKEQVELERKRRDEEIRRTNAAAANAANKELNEQVEISSLEQMGKLDPSSTIHDMFSFFPNEVYNSYEKLQYFSRDLNTAVSHPEIVFVGPRSSGKSSLIEAFIGRALNIVGGGNIVGVGGSNANGCSKRVLYLQFTNNIDFEVPKVTIKKDNTIKEFDHDIIVSIEQLNENLAKRNQLTNDYIEEPIYVSIESRTTLNLTLIDSPGLLFDQSQAESNKIESIVSSLLRPSHRLIIAVESCSQDWKSMSMGQYLKKIDPELSRSTFVFTKFHHTVRGFSSTRDINKYLSGTVPDIKGFFVTLPNHQVRASYSEANRFQEKIYQAHKRDMHALEQLQYDKRYERTIGVAPLRRYILNIVWKSYQDTIPRILKHLRSKRQTAEATLNELQKQSSSLDSTKLRSIASNYTVTFLQITEKLLSGTSEGNPSANGQTLDEEKSQQGDCGEWVDAYKEAIYIDPEEWNIPYWSSKLYGGQQLERLMAEFKAVCDNSKISEVKMDDIATASGINKLNNIPNYAWAASDLTSLISRDTFVPLIEQLCERAMYIMKRLTDIADKVIDSRRKSRCIGSSPFGGNGLNNINSGGNNGININDRLSNTDMDSLDQYPFFTHHVKNLYYDFVHRAAKGCKEKCMDEFYSSRTIYWELTEHPDSSLPSIRNDHHETKTAVCQLATKLFDSIRQRITKNVLLKLYNFFLVPMQTDLWNEIQAQITCLSNEQLEQLFEVQATREQLKQEEKKQQQILEKYSQIDEQFLKAASLFCRPLSNPTPSA", "length": 880 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55FX4-1", "protein_name": "SET domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDINSNHIKKINDFKDKGNKEFNKEKNKDKLNKRAITYFQLGIKYFNDEKHKIEINDQINKLISILYSNLSLMYLKGDEIILSLEASNKSIEFNNQNSKAFYYQSICKSYLCDYKGSMESIDKAISISKQDEKVVQQRNRLIEITNNKVKEDVYFENVLKNQKLENVAYENSIEKGRYLISKRLIKRGEEILRIAPFSFSLNGKYVSKFCGVCYQKKSIDNLLKCKDCDDFAICKECKAPNEPLSKYHPNDLCVLYKLNNEYYKMNNFEIANEDNKERGLTDERRLYINTIYNIFKNKTNNKAVVEVDNAISSSVIDVLNLSKKLLNHTNESQRAYSDSTKMKTDILELIFKSFYGANTLKKDEISNIIRIVDCNSHGYSDVISQKKKASGLYPFSCYTNHSCIPNSDYFIDKHGVMVLYASSDIQESEAITISYIYFLNRVEKRRKDLLNGHNFFCTCDQCSFQSSLTEEVCDKCNEIIPSTIGNSNLVYKEPKSLKETGFNYICPKGHTKSSLVYDIDNDQLYPTIAENYSKCKDLRNFRKINIFKEMLENRDFVKKLTPREFEVTPLAKYIANPKKSNSMLFEELINLVRGSVECGLTKSIEESNYSTYLVYDYYDLYKSLLLESKPQILKLNSIRDIIIKLLTPMVYNQNKPRIDKKLNKHLSNKINLKKNK", "length": 676 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55G93-1", "protein_name": "Tubulin-specific chaperone D", "gene_name": "tbcd", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MENSEDISLNSSEKSIESSVVNLEDQQQSQQQTQQQTCQKTFVQEAPELTILIDKLIQLKHSNKDELISNTTRIIYIIDQYLEQPTLLDIHLNDIIQPLINFIKSNYINNSNNNNTTTTTTTIMTETEIVIKKLSIKNSFRIIYVLSKVRGFKTIVKLFQHEAIDLLPVLDQLEISYHQWVNINKQRDRLNEISVSYSSGINLKNYIKPEEESEQEVVDENNNNINNNHNIDDEYNENIISWEEVYVLALWVSLLVIIPFKFSSLDSASSGTASAAGDGGDGDGDGQLKSISSRILKLGKLALSDVSKIRDSFSELLSKLLNRPDMKFEQKQFIKWCTNSIQLISNNNNNNNQNNSSNNNILLIIGIYSTLATMFKKGNRLDFLPIDMNLYEKIMEANKYLSLSGSERITKKIFLKLLQRIAIIMLPPVSASWRYQKIIKPLLLKGELIKQINNNNNNNNNENNNEEGEEEEEEIPEEIDEILEEIMKSLKDKDTIIRWTSAKAIGRIVNLLPKDMGDQVIGLVIDQMFEKNEFIDADPSAWHGGCLALAELARRGLLLPERLDVVVPLVIRALFFDIIKGTYSIGSHVRDSACYLCWALARTYHNSILSPYLLPICRNLVVVSLYDREINCRKSASAAFQEMVGRHQGLVPNGIEIVTSADFFTVGNKNNSFTSLTTFIGKFQIDYYPIVIKHLATIKIYNWDLEIRQLASKSIHLLTNINPNDIVSNYLPLIIPNTQSDLVHVKHGASLAISEILISLFENNNINLLSDNLKMMILMTIKNTKNEKLFKGKGGVLIRIGMCKIIYSICLVEFSLDKNLSEIKKPTESTSTNGNEDRAAALKLKIAMLKAKTASQINKPIITPPSSKSTTNNNNNNNNNNLNDNEIAFNIILGYLNENLNHPNEEVQKEASKAFELLFSKYISSNEKISLLLELIDSHCKTLKFDINRSARRGSSLLLGSLPFNSANLSYDLLSKVVNELILSIFQDDPKFKDIETRVNSISSLYKIGIYILNLIFKNQENEQKEEEDFKKSKNYNLFIKIWNCLGLATNDYSIDKRGDIGSWVRELSCKVLFDFIKFIITNQNSSTTTTTASTTDLSIENLINEKMITEFICKLFQLSGEKLDKIRDVACKIIHELLWIENPSSINNIPHKEELKKIIVKDQDVHFNWFRTEESLPLICKVLKFNCYLYPLLFGLFSSLGGTSKYLINDSIQSIKQYFSSFDNDEKERFEKIISFSKAILEITNNTTQRMIQPTFRSIYNLLSTHIFDFLIINNLNEQSIFETILFNCYQIIESNQDDIYLLLNSIELFSYFFIQFENNNNEYIKDYSLKALLLLLSNLKYPKVRKLASDQLKKSTRLFINNNGDDETPSLIKSLIFNTKWDDSVDLIIEPLKSLLLLLNQKHLLELLSENPTKKPIPLAPPITSIEELKDKIQNPHKQSDDNNNNNNGELINNNTENNNNNNFDDNLPEDSQDLMEI", "length": 1480 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55GP8-1", "protein_name": "Rho GTPase-activating protein gacO", "gene_name": "gacO", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSKLPPPPVQSSPQGFQLPSLHSVQLKPVRPPPQPTQQQLASNTSPREVGTSLSPQSPSNNINPSSSSSSPSSSIRQSPSSSPNVARKVPPTPTNNNGGPPTTTTTTTTTMPPPPAFIKKLSPSSSPILPKRIVSSPPLNGNTAPPPPPIVHLPPPPPTNLPPPPTLSPSSSTTTSPSSSSLNLSGGVPLPPRILRNSDGSANNNNNSNNNSNNNINSLNLSTSGGIPPPPSFFNNNNNNNNNSGSFVNSASSNGSPSLQSQNSVGYFKPPPPPVPTRSASLDPKQMGQFIKPQQNQNNSNNINNINNNNNNIILPPPPNININNNNFVPYIPSNNNQQQSTTPPPIVSISPLKRNSIDNSVVNKRLSQDLNTMLVNRLQHGLSPPVATPFFDDKILGSASKSAELKEKRDQEERERRERERIKKEKEDSEKKEKKEKKGKEEQEKKDKKKKEEQEKKDKKKKEEEEKKSKSSSSSSSSSKKSSSDNTIVNQNIFNNTLSQIMENQRDAQSLSPSSLPYPLILKLLTESIMSLNGPYTEGIFRITGSGTEVNRLKKQINEHDFSLDTQDPHVLAGLLKLWLRELVHPIIPSELYNDAIKSRSKEEVSRIISLIPDQNKEVLNFLIPFLKNVSQPHYAQYSKMDIDNVAMVFSPGLLRSTVLTTDLLLNSQYEKDFVKCLIEMSP", "length": 684 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55GR8-1", "protein_name": "Thiamin pyrophosphokinase thiamin-binding domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEKQEEEVQQQQQQQQQQQQPDKNNKETITWDVAEYGGYLFDKKLKAHNPLNHQMPLQYHHSQSTPHIPSSLSTSSTTSIKKPSSSLSDDESGGSSSSTPHSSNTPRKQFSFDDHCALILANQKLPKKLVDYFWDKCSVRICADGGANRLYSLGTKINQSSRWIPDYIKGDLDSLHEGVSDFFSKKGSSIVLDSSQDTSDLQKCFELIIDLEKGSGIKYRKIFILGGLGGSFSHEFANVNTLFDHPGRKIILASKDNLAWLLSSTYNHNIICRSETKCSLIPLSSKASQVTTSGLKWNLVKQSLNFGELISTSNVSLDNKVCVETSNPLIFIVDINP", "length": 337 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q561S0-1", "protein_name": "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial", "gene_name": "Ndufa10", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALRLLRLVPASASARGLAAGAQRVGRIHTSVHCKLRYGLLASILGDKTTKKLHEYSRVITVDGNICSGKNKLARDIAEQLGMKHYPEAGIQYSSSTTGDGRPLDIEFSGSCSLEKFYDNPKSNDGNSYRLQSWLYASRLLQYSDALEHLLSTGQGVVLERSIYSDFVFLEAMYNQGFIRKQCVDHYNEIKRLTLPEYLPPHAVIYIDVPVSEIQSRIQKKGDPHEMKVTSAYLQDIEDAYKKTFLPKMSEICEVLVYSSWEAEDSTKVVEDIEYLNYNKGPWLKQDDRTFHNLRMLVQDKREVLNYTTVPVYLPEITIGAHQGSRIYDSFRELPGRKYAPGYNADVGDKWIWLK", "length": 355 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q568T5-1", "protein_name": "Chondrolectin", "gene_name": "chodl", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MRATLRILCALTFLVSCSRGARVVSGQTVCQGNPEHPCYKIAYFKDVSSRVAFWEALQACEMDGGSLLSIENTAEQKHIEHLLRELSVSSSTGPASITDGDFWIGLTREEGDNAQEPGAFASCPNLYRWTDGSVSLFRNWYADEPSCGGEACVVMYHQPTALAGPGGPYLYQWNDDRCNMKHNFICKYEPESHLVKVQSDRPGGHDVDLSTEDKEDRRTPPTDEDESPRLIIAGPSSMLLIYVIIPTIPLLLLILVASGTCCFQMLSKSKPRTKTSVNQSTLWISKTPKIDSGMEV", "length": 296 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q5HYN5-1", "protein_name": "Cancer/testis antigen family 45 member A1", "gene_name": "CT45A1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTDKTEKVAVDPETVFKRPRECDSPSYQKRQRMALLARKQGAGDSLIAGSAMSKAKKLMTGHAIPPSQLDSQIDDFTGFSKDRMMQKPGSNAPVGGNVTSSFSGDDLECRETASSPKSQREINADIKRKLVKELRCVGQKYEKIFEMLEGVQGPTAVRKRFFESIIKEAARCMRRDFVKHLKKKLKRMI", "length": 189 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5I0J8-1", "protein_name": "PHD finger protein 11-like", "gene_name": "Phf11l", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAQEEPGGSNSVLNGDANSDKKMEKWTCALCPEGHDWSVIYFEPSSNIAAHENCLLYSSGLVECGPHDPRNPARSFAVKSVKKEIWRGRRLKCSFCNNKGATVGCDLQSCPKNYHLHCAKEDRAILQVDEDYGTYKLFCQRHAPGGQEPTQVDAAVKASFLKKCLEAGLLTELFEQIQQKMISIHGRFMDDTASESDYEGIKILLFDCGLFKDTLIKFEEAIKSKACECEERLNQMKQQLELLADLQQNLRSFQECGVLDPSGSTSGSLLPPEDHQCRCQESPEVQAGSGDSL", "length": 293 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5J3E6-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vom1r12", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDSKDLAIGVIFILQCSMGILRHFILLSYYLMLHYNKHSLKPIDLILMNMFIANFLIIFPKSMLQTVEAFGIKLLFSVFVCKFLLYIERVGRSVSIATVCLLSVFQAITISPRNSCLYGLKVKVPKYISLSIFLCWALYFVVNMILPVYAYIKWSSNNMTYKRTLKYCFSVGHDEFTGSFFTILFVFPEVFLAILIVWSGSSMVVILYRHKQQVQHIYCNYASTRTSPESRATKSIVVLVSVFICFYSISSILYGCIALFCDNSWSLINIANIISLCFPVLGSFVVSHNPDFPRFSLSWIRNTRRV", "length": 306 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5J3E9-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vom1r15", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVNDRMESKDLAVGVIFILQCSMGILRHFTLLSYYLMLHYNKHTLKPIDLILMNMFIANFLLIFSKSVLQTVEIFGMELFFNVFVCKFLLYIERVGRSVSVATVCLLSVFQAITISPRNSCLNGLKVKVPKYINLSIFFCWPLYFVINMILPVYGCIKWNSNNMTYKRSVKYCFSIGHDELTSSIFTILFVFPEVFLAILIVLSGSSMVVTLYRHKQQVQHIYCNYACTRTSPESRATKSIVVLVSVFICFYSVSSILYGCIALFCDDSWWLINIAHIISLCFPIFGSFLVSHNPALSRFSLSWIKNTRRV", "length": 311 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5J3F0-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "LOC100911184", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDFWNLAIRIIFLSQIIIGILGNVSLLFYYLVLYYREFTLKSTELILMHLMVANIIIIFSAGVPQTMTIWGMKQFLNDFGCKLLLYIHAVGRSVSICTTCLLSVFQAMTIRPQKFCGNDHKVTMERYLGCFISFLWVLYFLVNFIFLVYTYIKKNSNNETRKRDFGYCSTVGSDKISDSLYATLVMCPEVFFSVLIAWSSGSMIVILYRHKQKVKYIYSTHVSRRDYPESRATQNILAQMFTFLAFYTLSSTLRGSIALLSNHSWWLMNINHFTSLCFPSFGPFVLMSHYSIVSRFILFWLRKNCSNFLL", "length": 310 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5JQC4-1", "protein_name": "Cancer/testis antigen 47A", "gene_name": "CT47A1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSATGDRHPTQGDQEAPVSQEGAQAEAAGAGNQEGGDSGPDSSDVVPAAEVVGVAGPVEGLGEEEGEQAAGLAAVPRGGSAEEDSDIGPATEEEEEEEGNEAANFDLAVVARRYPASGIHFVLLDMVHSLLHRLSHNDHILIENRQLSRLMVGPHAAARNLWGNLPPLLLPQRLGAGAAARAGEGLGLIQEAASVPEPAVPADLAEMAREPAEEAAEEKLSEEATEEPDAEEPATEEPTAQEATAPEEVTKSQPEKWDEEAQDAAGEEEKEQEKEKDAENKVKNSKGT", "length": 288 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5QNN9-1", "protein_name": "Trace amine associated receptor 12e", "gene_name": "taar12e", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MMSLNETQTENILLCYPLLSNSCPKLHRLAVVQVGLYVFLLLMILTTVFGNLLIIISISHFKHLQSPTHLIVRSLAACDCLLGLLVMPYSMVRSVEGCWYLGDVVCKVHSSLDMTFCISSLLHLGLISVDRYWAICDPLRYRLRVTNITVTVFIVFIWLFSFVYSFYVVFSGVNTVGLETFIMQVYCVGSCVLYFNKQWGLICPILVFFLPGAIMSSLYMKIFHVARKHAKVMSERVTGGLKSQSSAQRERKAAKILAIVMGVFLFCWLPFFTVNALDPFFNFFTPADIFDAVIWFAYLNSTCNPLIYGFFYPCFQKAFKILIFTYICGVRNLDTFA", "length": 337 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q5QNP0-1", "protein_name": "Trace amine associated receptor 12g", "gene_name": "taar12g", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTSNESENIQLCYPLLSNSCPKLHRLAVVQVGLYICLLLMILTTVFGNLLIIISISHFKHLQSPTHLIVRSLAACDCLLGSLVMPNSMVRSVEGCWYLGDVVCKVHSSLDMTLCISSLLHLGLISVDRYLAICDPLRYRIRVTNTTVTVFTVFIWLFSVVYSFYVKFSGITAVGLEMLILQTYCVGRCVVFFNKQWGLICPVLAFFLPGAIMSSLYMKIFHVARKQAKVISERVTGGLKSQSSAQRERKAAKTLAIVMGVFLFCWMPFFTLTALDPFFNFLSSADVFDALFWFAYLNSACNPLIYGFFYPCFQKAFKILIFTYICGVKKANTLTFE", "length": 336 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q5R1F6-1", "protein_name": "T cell receptor alpha variable 5N-4", "gene_name": "Trav5d-4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTYAPTLFMFLWLQLDGMSQGEQVEQLPSILRVQEGSSASINCTYENSASNYFPWYKQEPGENPKLIIDIRSNMERKQTQGLIVLLDKKAKRFSLHITDTQPGDSAMYFCAAS", "length": 114 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5RKI7-1", "protein_name": "Solute carrier family 7 member 13", "gene_name": "Slc7a13", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAMDIEKKIYLKRQLGYFWGTNFLIINIIGAGIFVSPKGVLQYSSMNVGVSLCVWVFCAVLSMTSTLCAAEIGITFPYTVAHYYFLKRCFGPFVAFLRLWTSLFTGPGVLASQALLLAEYGIQPFYPSCSAPAVPKKCLALAMLWIVGILNSRGVKELSWLQTVSMVLKMGILSFISLSGLFLLVTGRKENVRRLQNAFDAEFPEVSRLIEAIFQGYFAFSGGGSFTYVAGELKEPSKTIPRCIFTALPLVTVVYLLANLSYLTVLSPQELLSSDAVALTWTDRVIPQLTWSVPFAISASLFSNLVTSVFETSRTSYIASRNGQLPLLCSTLNVHSSPFIAVLLDVSMGSIAIVLTNLIELINYLFFVFSIWTVLSVIGILKLRYQEPNLHRPYKVFSPFLFITAAISLSMVLIPLIKSPKMQYIYVFLFFLGGLLFYVPLIHFKLKLIWFQKLTCYLQLLFNICIPDVSDEHVAEEES", "length": 479 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5XHX8-1", "protein_name": "Sperm microtubule associated protein 2", "gene_name": "Spmap2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGELGEHRSRSSLLSIPVLDTKTSGGSEYRESDGSLDLQSTLFEDHWLQSSQATTERNTDDPEEEIPPEEMVGEELPEVSNLEDSLRRDLEVEVVGMSHLSINERTTPTTSSAKCRKKKNHRLLELAKPKFNWQCLKDRTGRCCKGHVWISPRKTNLQFCLYWPSVYWTERFIEDTTLTITVPEVSRRVEELSRPKRFYQEYYNNNRTTPIWPIPRSTLEYQASNRLKRLATPKIRNNIWSINMSEVSQVSRAAQMAVPTPRTLRLAKPRAPATLLEEWDPMPKPKPYVSDYNRLLQLATPKALSEKCVPDRSPQWEVLNVTKNAVASSRIISLAQPKIRKDLNEGYNPYYISPASLVAQASPRIYELAVPKHITKKV", "length": 378 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q63550-1", "protein_name": "BPI fold containing family A, member 2F", "gene_name": "Bpifa2f", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFQLGSLVVLCGLLIGTSGSLFDIFQNPELDVESVWSEINYRIRYALETMDLDMLADYLSKRGIELKIKDLRILNLNHEVSPNGDEVTLKMPMALNASLSLPARDLTTDVSISMEAITSFAIEKDPKTGRRVLNMQRCSLNTDNTSISLLNRKSNFVNLALDSALYLIKRGLTLPVRRQLCPVLQLIISNTFHPDEISNPQTAIST", "length": 206 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q64583-1", "protein_name": "Cytochrome P450 2B15", "gene_name": "Cyp2b15", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MELGVLLLLTFTVGFLLLLASQNRPKTHGHLPPGPRPLPFLGNLLQMNRRGLLRSFMQLQEKYGDVFTVHLGPRPVVILCGTDTIREALVDQAEAFSGRGTVAVLHPVVQGYGVIFANGERWKILRRFSLVTMRNFGMGKRSVEERIKEEAQCLVEELKKYKGALLNPTSIFQSIAANIICSIVFGERFDYKDHQFLRLLDLIYQTFSLMGSLSSQVFELFSGFLKYFPGVHKQISKNLQEILNYIDHSVEKHRATLDPNTPRDFINTYLLRMEKEKSNHHTEFHHQNLVISVLSLFFTGTETTSTTLRYSFLIMLKYPHVAEKVQKEIDQVIGSHRLPTLDDRTKMPYTDAVIHEIQRFADLIPIGLPHRVTNDTMFLGYLLPKNTEVYPILSSALHDPRYFDHPDTFNPEHFLDVNGTLKKSEAFLPFSTGKRICLGEGIAQNELFIFFTAILQNFSLASPVAPEDIDLSPINSGISKIPSPYQIHFLSRCVG", "length": 495 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q66X01-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 9C", "gene_name": "Nlrp9c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVDSSSYGLLQYFQKLSDEEFQRFKELLQKEQEKFKLKPLSWTKIKNTSKEDLVTQLYTHYPRQVWDMVLNLFLQVNRKDLSTMAQIERRDKQNKYKEFMKNLFQYIWTSETNTYMPDRSYNTIIDRQYKALLDIFDSESDPATAVVLGTRGKGKTVFLRKAMLDWASGVLLQNRFQYVFFFSVFSLNNTTELSLAELISSKLPECSETLDDILSNPKRILFVLDGFDYLKFDLELRTNLCNDWRKRLPTQNVLSSLLQKIMLPECSLLLELGESSCSKIIPLLQNPREIIMSGLSEQSIYFYCVSFFKIQLGVEVFKDLKKNEPLFTLCSNPSMLWMICSSLMWGHYSREEVISSSESTSAIHTIFIMSAFKSIFGLGSSKYKRFKLKTLCTLAVEGMWKQVYVFDSEDLRRNKISESDKTVWLKMKFLQIQGNNIMFYHSTLQWYFATLFYFLKQDKDTYHPVIGSLPQLLGEIYAHKQNQWTHAQTFFFGIATKHVITLLKPCFGNISFKTIRQEIIRYLKSLSQPECNEKLVHPKKLFFCLIENQEERFVSQVMNLFEEITVDISDSDDLGAAEYSLLRASKLKNLHLHIQKKVFSEIHDPEYGSLENFKLDQKFSAINWTMLSILFCNLHVLDLGSCHFNKKVIEVLCNSLSPTPNMPLTVFKLQRLLCSFMTNFGDGSLFCTFLQIPQLKYLNLYGTDLSNDVVEMLCSALKCSTCRVEELLLGKCDISSEACGIMATFLINSKVKHLSLVENPLKNKGVMFLCKMLKDPSCVLESLMLSYCCLTFIACGHLYEALLSNKHLSLLDLGSNFLEDIGVNLLCEALKYPNCTLKELWLPGCYLTSECCEEISAVLTCNKNLKTLKLGNNNIQDTGVKRLCEALCHPKCKVQCLGLDMCELSNDCCEDLALALITCNTLKSLNLDWNALHHSGLVMLCEALNHKKCKLNMLGLDKSSFSEESQTFLQAVEKKNNNLNVLHFPWVEDELKKRGVRLVWNSKN", "length": 1004 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q675C0-1", "protein_name": "Taste receptor type 2 member 102", "gene_name": "Tas2r102", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEPVIYSFATLLIHVEFIFGNLSNGFIVLSNFWDWVIKRKLSTIDKILLTLAISRITLIWEIYTWFTSVYGPSSFAIGMKLQILYFTWILSSHFSLWFATALSIFYLLRIANCSWKIFLYLKWRLKQVIVGMLLASLVFLPGILTQRTLEERPYRYGGNTSEDSMETDFARFTELILFNLTIFSVIPFSLASISFLLLIFSLWKHLRKMQLSSRGHGDPSTKAHTNALRIMVSFLLLYSIYFLSLLLSWIAQKHHSKLVDIIGIITGLMYPSAHSFILILGNSKLMQTSLWILSHLRCRLKGENILNPSGNQVTSCYIFCIANKSVS", "length": 327 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q68FP3-1", "protein_name": "C-C motif chemokine 6", "gene_name": "Ccl6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRHSKTAISFFILVAVLGSQAGLIQDTVKEDRPFNPTIIHQGFQDSSDCCFSYASQIPCSRFIYYFPTSGGCTKPGIIFVTRKRKRVCANPSDQRVQTCISTLKLGPRSGNSAIA", "length": 115 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6EKJ0-1", "protein_name": "General transcription factor II-I repeat domain-containing protein 2B", "gene_name": "GTF2IRD2B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAQVAVSTLPVEEESSSETRMVVTFLVSALESMCKELAKSKAEVACIAVYETDVFVVGTERGCAFVNARTDFQKDFAKYCVAEGLCEVKPPCPVNGMQVHSGETEILRKAVEDYFCFCYGKALGTTVMVPVPYEKMLRDQSAVVVQGLPEGVAFQHPENYDLATLKWILENKAGISFIINRPFLGPESQLGGPGMVTDAERSIVSPSESCGPINVKTEPMEDSGISLKAEAVSVKKESEDPNYYQYNMQGSHPSSTSNEVIEMELPMEDSTPLVPSEEPNEDPEAEVKIEGNTNSSSVTNSAAGVEDLNIVQVTVPDNEKERLSSIEKIKQLREQVNDLFSRKFGEAIGVDFPVKVPYRKITFNPGCVVIDGMPPGVVFKAPGYLEISSMRRILEAAEFIKFTVIRPLPGLELSNVGKRKIDQEGRVFQEKWERAYFFVEVQNIPTCLICKQSMSVSKEYNLRRHYQTNHSKHYDQYTERMRDEKLHELKKGLRKYLLGSSDTECPEQKQVFANPSPTQKSPVQPVEDLAGNLWEKLREKIRSFVAYSIAIDEITDINNTTQLAIFIRGVDENFDVSEELLDTVPMTGTKSGNEIFLRVEKSLKKFCINWSRLVSVASTGTPAMVDANNGLVTKLKSRVATFCKGAELKSICCIIHPESLCAQKLKMDHVMDVVVKSVNWICSRGLNHSEFTTLLYELDSQYGSLLYYTEIKWLSRGLVLKRFFESLEEIDSFMSSRGKPLPQLSSIDWIRDLAFLVDMTMHLNALNISLQGHSQIVTQMYDLIRAFLAKLCLWETHLTRNNLAHFPTLKLVSRNESDGLNYIPKIAELKTEFQKRLSDFKLYESELTLFSSPFSTKIDSVHEELQMEVIDLQCNTVLKTKYDKVGIPEFYKYLWGSYPKYKHHCAKILSMFGSTYICEQLFSIMKLSKTKYCSQLKDSQWDSVLHIAT", "length": 949 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6NXT2-1", "protein_name": "Histone H3.3C", "gene_name": "H3-5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MARTKQTARKSTGGKAPRKQLATKAARKSTPSTCGVKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFNTDLRFQSAAVGALQEASEAYLVGLLEDTNLCAIHAKRVTIMPKDIQLARRIRGERA", "length": 135 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6P3W6-1", "protein_name": "NBPF family member NBPF10", "gene_name": "NBPF10", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVVSAGPWSSEKAEMNILEINETLRPQLAEKKQQFRSLKEKCFLTQLAGFLANRQKKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDASRSLYEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEAEKVLESSAPREVQKAEESKVPEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVNSTLVVDRESSHDECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLSGFLANQQKKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLKEKLREGRDASRSLNEHLQALLTPYEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPREMQKAEEKEVPEDSLEECAITYSNSHGSYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKGPEVLQDSQDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGFAFDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDEEEEEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLEEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGFAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDEEEEEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLEEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGFAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDEEEEEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDEEEEEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGYLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELCDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDKIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLNGVLMEVEEREVLQDSLDRCYSTPSMYFELPDSFQHYRSVFYSFEEQHISFALYVDNRFFTLTVTSLHLVFQMGVIFPQ", "length": 3795 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6UGQ3-1", "protein_name": "Secretoglobin family 2B member 2", "gene_name": "Scgb2b2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLALLVTGELGFQRTEACIPFFGVYLGILSGNRIGLHTELAPFDPTVEEKEAFEKIQDCYEEEGLKAKTEDMKLMTTILFSSECRSYYTKEVLKNILVKFSKKLTHGS", "length": 114 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6YCH2-1", "protein_name": "TD and POZ domain-containing protein 4", "gene_name": "Tdpoz4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSGELEAKSRGDTQSHEQKLCYRWTISNFSFFVEETEEYITSLVFSLEDNDKMTWCLRVYPTGVDEKNKDYVSLYLILLSCEKGSVWAKFEVCILNAKGEKCNTERIPSFSRIQPHQPFGFEKFITRDSFLSPAQVLTPDDKFTLLCKVSVLQDSFSISGQNPRPAIKVTRCTLENDVGELWENPLFTDCSLLVAGHEFRAHKAILAARSPVFRAMFEHEMEERLTNCVEIHDLDPQVFKEMMGFIYTGKVPHLHSHSMACDLLAAADRYGLEDLMVMCEDALCRSLSVENAAHTLIVADLHSTEHLKTQALDFIIVYASEVSKTSGWMSMVESHPRLVAEAFHSLASAQRVFWALPFKQLKWSLRPTQL", "length": 370 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6ZMA2-1", "protein_name": "Olfactory receptor", "gene_name": "Or1o1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNCTQSPGFILLGLSSDPEKWQLFFSIFLALYLLGFLGNLLLLLAIGADVHLHTPMYFFLSQLSLVDLCFITTTAPKMLEALWTGDGSISFSGCLTQMCLFGVFADMDNLLLAVMAIDRYAAICQPLLYPLLMTPCRCGVLACGSWGIAHCASLVYTLLLSQLSFHSNQEIPHFFCDSRPLLWLSCSDTHLNEFLMMVLSALLGISALLCIVSSYGCIFCAVARVPSAKGRRKALATCSSHLSVVLLFYSTVFATYLKPPSTSHSSGEVVAAVMYTLITPTLNPFIYSLRNKDVKNSLKKLLNMEKPLD", "length": 309 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q70YC5-1", "protein_name": "Protein ZNF365", "gene_name": "ZNF365", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQQKAFEESRYPWQESFENVAVCLPLRCPRCGDHTRFRSLSSLRAHLEFSHSYEERTLLTKCSLFPSLKDTDLVTSSELLKPGKLQSSGNVVKQKPSYVNLYSISHEHSKDRKPFEVVAERPVSYVQTYTAMDLHADSLDGTRSGPGLPTSDTKASFEAHVREKFNRMVEAVDRTIEKRIDKLTKELAQKTAELLEVRAAFVQLTQKKQEVQRRERALNRQVDVAVEMIAVLRQRLTESEEELLRKEEEVVTFNHFLEAAAEKEVQGKARLQDFIENLLQRVELAEKQLEYYQSQQASGFVRDLSGHVLTDISSNRKPKCLSRGHPHSVCNHPDLKAHFHPKGRNHLKKAKDDRASMQPAKAIHEQAESSRDLCRPPKKGELLGFGRKGNIRPKMAKKKPTAIVNII", "length": 407 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q71LE2-1", "protein_name": "Histone H3.3", "gene_name": "H3-3A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MARTKQTARKSTGGKAPRKQLATKAARKSAPSTGGVKKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSAAIGALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA", "length": 136 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q7KR10-1", "protein_name": "Probable cytochrome P450 12d1 distal, mitochondrial", "gene_name": "Cyp12d1-d", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MNTLSSARSVAIYVGPVRSSRSASVLAHEQAKSSITEEHKTYDEIPRPNKFKFMRAFMPGGEFQNASITEYTSAMRKRYGDIYVMPGMFGRKDWVTTFNTKDIEMVFRNEGIWPRRDGLDSIVYFREHVRPDVYGEVQGLVASQNEAWGKLRSAINPIFMQPRGLRMYYEPLSNINNEFIERIKEIRDPKTLEVPEDFTDEISRLVFESLGLVAFDRQMGLIRKNRDNSDALTLFQTSRDIFRLTFKLDIQPSMWKIISTPTYRKMKRTLNDSLNVSQKMLKENQDALEKRRQAGEKINSNSMLERLMEIDPKVAVIMSLDILFAGVDATATLLSAVLLCLSKHPDKQAKLREELLSIMPTKDSLLNEENMKDMPYLRAVIKETLRYYPNGFGTMRTCQNDVILSGYRVPKGTTVLLGSNVLMKEATYYPRPDEFLPERWLRDPETGKKMQVSPFTFLPFGFGPRMCIGKRVVDLEMETTVAKLIRNFHVEFNRDASRPFKTMFLMEPAITFPFKFTDIEQ", "length": 521 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q7M715-1", "protein_name": "Taste receptor type 2 member 117", "gene_name": "Tas2r117", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKHFWKILSVISQSTLSVILIVELVIGIIGNGFMVLVHCMDWVKKKKMSLVNQILTALSISRIFQLCLLFISLVINFSYTDLTTSSRMIQVMYNAWILANHFSIWIATCLTVLYFLKIANFSNSFFLYLKWRVEKVVSVTLLVSLLLLILNILLTNLETDMWTNEYQRNISCSFSSHYYAKCHRQVLRLHIIFLSVPVVLSLSTFLLLIFSLWTHHKRMQQHVQGGRDARTTAHFKALQTVIAFFLLYSIFILSVLIQIWKYELLKKNLFVVFCEVVYIAFPTFHSYILIVGDMKLRQACLPLCIIAAEIQTTLCRNFRSLKYFRLCCIF", "length": 330 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7M719-1", "protein_name": "Taste receptor type 2", "gene_name": "Tas2r115", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MCAVLRSILTIIFILEFFIGNLGNGFIALVQCMDLRKRRTFPSADHFLTALAISRLALIWVLFLDSFLFIQSPLLMTRNTLRLIQTAWNISNHFSIWFATSLSIFYLFKIAIFSNYLFFYLKRRVKRVVLVILLLSMILLFFNIFLEIKHIDVWIYGTKRNITNGLSSNSFSEFSRLILIPSLMFTLVPFGVSLIAFLLLIFSLMKHVRKMQYYTKGCKDVRTMAHTTALQTVVAFLLLYTTFFLSLVVEVSTLEMDESLMLLFAKVTIMIFPSIHSCIFILKHNKLRQDLLSVLKWLQYWCKREKTLDS", "length": 310 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7RTZ2-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 1", "gene_name": "USP17L1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGDDSLYLGGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSSETRVDLCDDLAPVARQLAPREKLPLSSRRPAAVGAGLQNMGNTCYENASLQCLTYTLPLANYMLSREHSQTCQRPKCCMLCTMQAHITWALHSPGHVIQPSQALAAGFHRGKQEDVHEFLMFTVDAMKKACLPGHKQVDHHCKDTTLIHQIFGGCWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVKQALEQLVKPEELNGENAYHCGLCLQRAPASNTLTLHTSAKVLILVLKRFSDVAGNKLAKNVQYPECLDMQPYMSQQNTGPLVYVLYAVLVHAGWSCHDGHYFSYVKAQEVQWYKMDDAEVTVCSIISVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRAKQGELKRDHPCLQAPELDEHLVERATQESTLDHWKFLQEQNKTKPEFNVGKVEGTLPPNALVIHQSKYKCGMKNHHPEQQSSLLNLSSTTRTDQESMNTGTLASLQGRTRRAKGKNKHSKRALLVCQ", "length": 530 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q7TMR7-1", "protein_name": "Monocarboxylate transporter 7", "gene_name": "Slc16a6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTQKNSKLCSRANVYTQVPDGGWGWVVAASFFFIEVFTYGVIKSFGVFFNDLMDSFDESNSKISWIISICVFIMTFTAPLSTILTNRFGHRLVVMGGGLLISVGMIAASFSQRVYQMYISIGIVSGLGYCFSFLPTVTILSQYFDKRRSMVTAVASTGECFAMFAFAPAITALKEHIGWRYSLLFVGLLQLNVMVCGALLRPIIIKGPGSPKAIPLEPRREVQYMLENEKTRTSIDSIDSGVELTTSPKNVPSEAKREQEVRVEQQQTLVVGPKHSQKRAPLLDFSILKDRSFICYTLFGLFATLGFFAPSLYIIPLGISLGIHPDRAAFLLSTMAIAEVFGRIGMGLVLNREPIRKIYIELICVILLTVSLFAFTFATEFWGLMLCSVFFGSMVGTIGGTHIPLLAEDDVVGIEKMSSAAGVYVFIQSISGLAGPPLAGLLVDQSKIYSRAFYSCAAGMALAAVCLALVRPCKKGLCQNPHSGENQTDGHRGKALQDIPEDFLEMDLGKCEPRAHMKMDPV", "length": 522 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7TN50-1", "protein_name": "Mas-related G protein-coupled receptor member B8", "gene_name": "Mrgprb8", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDSSIPDPEADLIQLNGSYHTETSPCVIESRVMILLSIIIAFFGLAGNAMVLWLLAFRMRRNVFSVYILNLAGANFLFLCTHTAFSLEKIIVLFHSVHIHIPLLFYTLSTLAYLAGVSMVTAISAEYWLSGIWPYWYQGQRLKHTTTVICTGLWGLALLLSLLEGKSCGFLGSTYNQDVCWKLDFIIVAWLLVLFAVLSRSIQVLLVRIFCGSQRTPVTKLHVTIVLTALVLVICGFPFGIIFYLLYWTTEVYYIMPCNSFHETILLLSYINSCANPIICLLVGSIRHCRFQCGTLRLLLHRAMQDIPEEEGEELEEVVGERVQNSIP", "length": 328 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7TPX8-1", "protein_name": "Oogenesin-2", "gene_name": "Oog2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNFYSPPTLMELARQCLLRDEYLAISALKDLPNMMFPVMFKEAFIDGHTKILTAMIPVWPFPYLSVGTMLKNLNLDTLKAVLEEIDILISKPVFSSRCKLREITLSHDLVVVWAGSHEVEGLPEFMEQEKPVENSPGYGTKNKLKVTTELQFMEGHLDECSTYLLQWAYQREDSIHLHCRKLKIYGLTKAAVIEMFKIVHAEYIEDLELSCLCLEYLDFLNPYLKQMSNLLSLTLDEIIYTLNIDDYRNLNEEKVITVISHLPTFHHLQELYVHGVIFIECLRCLKKPLEVLSFTDCDLSQSDLDYLPYCLNIFELRSLHLTDVRLSNLLLEPLGFLLERVRHTLKSLQLMSCEMGETHFNALLPALSQCYQLTVVNFYGNELSLLFLKKLLHHTAKLSQLADELYPAPQECYDNRDVVLSHRLENFCSELLDILRAIREPKKVTFGTIKCSKCGGSYVYDLETQCCFFEKNPPWA", "length": 476 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7TQY5-1", "protein_name": "Olfactory receptor", "gene_name": "Or4k38", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEDSNRTVSSEFIFQGLCSSRQLEIFLLLPFSILYLMAVVGNLFVVILIIIDHHLHSPMYFLLANLSFIDFCLSSVTTPKLTIDLLKENKTISFVGYMRQIVCVHFFAGGEMVLLVTMAYDRYVAICRPLHYSSIMDRQKCIWLVVISWIVGFVHAISQMLLILDLPFCGPRVIDSFFCDIPLVMKLACMNTDTLEILINADSGILATTCFILLLISYTYILLTVQHRSKDGSSKALSTCTSHIIVVLLFFGPIIFIYLWPVSITWVDKFLAVFYSVITPLLNPAIYTLRNKDIKNAIKKLISHK", "length": 305 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7TR72-1", "protein_name": "Olfactory receptor", "gene_name": "Or8k25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEKYNLTIVTEFILVGITNHHEFQVPLFGLYLIIYLTSLVDNLGMIILTIVDSRLQTPMYFFLRHLATTDLGYSTAVGPKMLRNFLVDQNIISFYACAIQSSFFGMFIVCEFFILSAMSYDRYVAICKPLLYTVIMSQKACWILVTIPYLYSIIVSLLVNIKIFTLSFCGYNVISHFYCDALPLLTLACSNTHEIEAIILIFSAFNLLSSLLIVIGSYLLILMAILRINSAEGKWKAFSTCGSHLTVVIVFYGTLIFMYLQPTFTHSIDTGKVISIFYTQVIPMLNPLTYSLRNKDVKDVLKKPMEKVHNLFS", "length": 313 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7TSF0-1", "protein_name": "Desmoglein-1-gamma", "gene_name": "Dsg1c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDWHSFRIAALLLTSLVVLEVNSEFQIQVRDHNAKNGTIKWHSIRRQKREWIKFAAACREGEDNSKRNPIAKIHSDCAANQPVTYRISGVGIDQPPYGIFIINQKTGEINITSIVDREVTPFFIIYCRALNAQGQDLENPLELRVRVMDINDNPPVFSMTTFLGQIEENSNANTLVMKLNATDADEPNNLNSMIAFKIIRQEPSDSPMFTINRKTGEIRTMNNFLDREQYSQYSLVVRGSDRDGGADGMSAESECSITILDVNDNIPYLEQSSYDITIEENTLHSQLLQIRVIDLDEEFSDNWKAIIFFISGNEGNWFEIEMNERTNVGTLKVVKPLDYEAVKNLQLCIGVRNVAEFHQSIISQYRLTVTLITVTVLNVVKGCVFQPGSKTFIVDSRMEANHTVGEFLATDCETGQATNKFKNVRYRYVMGNNPENLLVVDSGIITLRNRVTMEQYERLNKRYEGTVLSIHDSLQRTCTGTIIMVLCGFWTTTEHPTTSTEKPVTLSITPNVDNVHFGPAGIGLLIMGFLVLGLVPFLLISCDCGGAPGGGAGFEPVPECSDGAIHTWAVEGPQPGGITTICVPQMPPGNANVIEYIDNSGVYTNEYCGREMQDLGGGERTTGFELMDGVKTSAAPEICQEYSGTLRRNSMRECRDGGLNMNFMESYFCQKAYAYADEDEGRPSNDCLLIYDIEGVGSPAGSVGCCSFIEDLDESFLDTLGPKFKKLADISLGKEIDSYPDPDPSWPPQSTEPICPQHMEQLASGHPSISPHFGKTTVISENAYPSGPGVQHPMLIPDPLGYGNITVRESYTTSGTLKPSVHFHDNQQASNVVVTERVVGPISGADLHGMLEIPALRDGTNVIVTERVIAPGSSLPNSLTIPNPRETSNVVVTERVIQPTSGMIGNLSIPP", "length": 911 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q803M0-1", "protein_name": "Protein phosphatase 1 regulatory subunit 3B", "gene_name": "ppp1r3b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MPIELAMSLYLSSDEFLNPRASKYSRPLQPCLNQCKSSKLSFSSLKEQSEFNGVSRALMIPGRAKKHVSFADHKGLALTVVKIFSEFDDPIDIPDNIDNFFTSSLTVSEGKDKLTLDFDQPSADYLKFRQRIENDHVCLEHCMLKEKSIMGTVKVKNISFEKSVKLRITFNTWKNHTDVECQYVKDTYTGSNRDTFSFEASLPEQVPSHERIEFAICYEVNGDTLWDNNQGKNYRIIQSALRKSSNESNGGHQQYSQSDWDIHFDRYGSPRCSRGIFPHWPSYVGYEDIGPYY", "length": 293 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q80SW5-1", "protein_name": "Embryonic testis differentiation protein", "gene_name": "Etd", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDEKNPEAVPRPPEQNTELVPPKKSKSKKPANILIYLIDRHLGRPRNDMDLFEWVWTLK", "length": 59 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q80VJ6-1", "protein_name": "Zinc finger and SCAN domain containing protein 4C", "gene_name": "Zscan4c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASQQAPAKDLQTNNLEFTPTDSSGVQWAEDISNSPSAQLNFSPSNNGCWATQELQSLWKMFNSWLQPEKQTKEQMISQLVLEQFLLTGHCKDKYALTEKWKASGSDMRRFMESLTDECLKPPVMVHVSMQGQEALFSENMPLKEVIKLLKQQQSATRPTPDNEQMPVDTTQDRLLATGQENSENECNNSCNATEANVGESCSGNEMDSLLIIQKEQHPEHEEGNVVCQFPHGARRASQGTPSHHVDFPSAPTTADVPMEEQPKDLSRENISEDKNNCYNTSRNAATQVYSGDNIPRNKSDSLFINKRIYHPEPEVGDIPYGVPQDSTRASQGTSTCLQESLGECFSENDPREVPGLQSRQEQPISDPVLLGKNHEANLPCESHQKRFCRDAKLYKCEECSRMFKHARSLSSHQRTHLNKKSELLCVTCQKMFKRVSDRRTHEIIHMPEKPFKCSTCEKSFSHKTNLKSHEMIHTGEMPYVCSLCSRRFRQSSTYHRHLRNYHRSD", "length": 506 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q80VT8-1", "protein_name": "S100 calcium-binding protein, ventral prostate", "gene_name": "S100vp", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAQNLTSTEQEIMELLMILQEFSVKKIDKLDVQEVKRLFREELPNFLKAMDEATKNKILNDKGKEMPFDEIWDMIGRMALEYRKKNSNALKD", "length": 92 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q80XZ1-1", "protein_name": "Polypyrimidine tract-binding protein", "gene_name": "Smptb", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSRNSPPAAEGNGSKRFKGDSWGTRDPSRLVHILRLPSCVTEGEILCLALPFGEVSNLLFLRAKNQAFVEMSTEESANTMINYYTWMPPVLRGQPVHIQFAHYRELKVSSSPSQEISLSQAGDSREATASSLVAVPGQAAASGQTAVPSQLGAQPCLPPEDSYQAGTVALAPPASAVDTELVVAWQSPVLRILVENYFYRVTLEVLHQIFSRFGTVLKIITCTKNNRFQALLQYAHVMSAERAKLFLDGQNIYDACCTLRISFSGLTNLMVKYNNDKSRDYMRPDLPSDDSQPSPVQVQNMASALPAPAMSSASPYASIALPHTFAIPQAAGLANPEVFKTLHPQAIQEVAMASSSSSSSTAAAAVGAAEIAAAAVPGAEGSMVTSGSPGVGSPVLLVANLNQEKVTPRSLFILFGAYGDVHRVKILFNRKENALVQMADGSQAELALRHLNGHKLYGKALCILLSKHQSVKLPREGKEDQGLTKDYANSPLHRFKKPGSKNFQNIFPPSATLHLSNLPSLVSEEELKNLFSSNGYAVKAFRFFPKNHKMALIRMGSTEEAIQALVDLHGHLLGQNHHMRVSFSRMTI", "length": 588 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q810J1-1", "protein_name": "Pregnancy-specific glycoprotein 22", "gene_name": "Psg22", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEVSSELLSNGWTSWQRVLLTASLLTCWLLPITAGVTIESVPPKLVEGENVLLRVDNLPENLRVFVWYRGVTDMSLGIALYSLDYSTSVTGPKHSGRETLYRNGSLWIQNVTREDTGYYTLQTISKNGKVVSNTSIFLQVNSSLFICGRPSPPALLTIESVPASVAEGGSVLLLVHSLPDNLQSLLWYKGLTVFNKVEIARHRTVKNSSEMGPAYSGREIVYSNGSLLLQNVTWEDTGFYTLQIVNRYWKMELAHIYLQVDTSLSSCCDDFNSVQLRINPVPPHAAEGERVLLQVHNLPEDVQTFLWYKGVYSTQSFKITEYSIVTESLINGYAHSGREILFINGSLLLQDVTEKDSGFYTLVTIDSNVKVETAHVQVNVNKLVTQPVMRVTDSTVRIQGSVVFTCFSDNTGVSIRWLFNNQNLQLTERMTLSPSKCQLRIHTVRKEDAGEYQCEAFNPVSSKTSLPVRLTVMNE", "length": 475 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q863C3-1", "protein_name": "Gastrin-releasing peptide", "gene_name": "GRP", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRGREVPLVLLALVLCLAPRGWAAPVTAGRGGALAKMYTRGNHWAVGHLMGKKSVAESPQLHEEESLKEQLREYAQWEEATRNLLSLLQAKGARGHQMPPWEPLSIHQPAWDSEDVSNFKDTGPQHEGRNPQLN", "length": 134 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q869X2-1", "protein_name": "Probable polyketide synthase 17", "gene_name": "pks17", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTFNNIKDENNDDIAIIGMGFRFPGGGNNPYQFWNQLSNKMDGISKIPTEKWSRSFYEQKYINNEYGGVLKDEEWKNFDPLFFGISPKEAPIIDPQQRLLMTTLWEAFEDANIKPSTFRGSDTAVFIGMMNTDYQRCQFRDISYVNPYITPGTAGSFISNRLSFSFDLRGPSMTLDTACSSSLNAVYLGCQAIANGDSKMAIVGGVNGIFDPCFSMTFSGLNMLGHKGQCRSFDAGADGYIRSEGGGVCILKKYSDAIKDGDRIYCVIKGGSSNVDGYNAKTNIIQPSMKAQGENIEIALKKSGVNPSDIYYIEAHGTGTPVGDPIEIEAISRIFKDNHTPDAPLYIGSVKSNIGHLESAAGIASLIKVALSLKNRSLVPNIHFEKPNPLIKFEDWNIRVVTDEIQFPINKLINMGINCFGLSGSNCHMILSEAPINYDELLKTTNNNSTSSSSNDDKKEYLIPFSANCNISLDKYIEKLISNQSIYKDTILFKDFVKHQTISKSNLIKRKVITASDWDDFLNKRNETTSTSSLTSTISAPASSTPVIYVFTGQGPQWRDMGKALYETESVFKDAIDHCDKLLANYFGYSILQKLLSLESEDSPEIHHPILAQPSIFLIQVGLVALYKSFGISPSIVVGHSFGEIPSALFSDVISLETAVKIVYYRGLAQNLTMGTGRLLSIGIGADAYLEKCALLYPEIEIACYNDPNSIVITGSEQDLLGAKSTLSAEGVFCAFLGTPCSFHSSKQEMIKEKIFKDLSDLPESNVPCVPFFSTITGSQLSHKGFYNVQYIYDNLRMPVEFTKAISNIFNFIEENESYKNAIFLEIGPHPTLGFYIPKCKPSNSTITSKPIIVSPLHKKKEELTQFKLAISTLYCNGVEIDFASGQQLLPTSSSSGGGDISSFKESTNKLPRYQWDFEEYWDEPNQSKMVKRGPSNNLLGHDQFAGNTLMELFIDIDKSAHQYLKGHKIKGKYLFPGSGYIDNILRQFNGQDITIFNLEFSNPFFLKDGVQHHLQTSITPTTKGEFKVEFFIKDNRNSTKWTKTSNGRIGLFKHNPKNNKLDIEKLKSQCSFTTLTKSEVYNKLLLLSLPYGPTFQRVESCSIGDGCSFFKLSMSPCSEFDKDFLNPSIIDCAFHGLLVLSEGPQEIVFDRLQDMKFYSSNVPSTRPQFIYAFAKFDKIEGNSTHGSLNIILEDGTLLISIKNVKCTSLIRLKKQSIKYPSQNVYSHHWQSKDSPLTLIENQLIEEKSSESKINFEKLLNDKLFNYYLIRLLNQSIKSEFIEFDYKTSTVDTLDIGSKNAKLLEKIQSILNPIDSLDQSIDITSLKQAIIVKSSFKNEIKLVEKSIKRIVSLLKGGESEHFSPSNPSSPNDTPRNNSNNCSSKNNAASSDDADDDTNNEETINQLNNEPFNFSNSQFISNQNQLISKTIVNSFDRLINSIEIGEKKLIKIIDLSSIYQNYQLSKLLLLQLNQLLINLSNNNNIEIEYTIPSNTKNIDSITEETKSISNVLNIKYRSFDLQDDLESNGYLNSNYDLIITSLLLVSTNSIDSNEVLSKLYKLLLPKGQLILMEPPKGVLSFNLLFANDFKQSLEIKSEQEIKSLIIYCGFTKIETNLNTKDDEEQQQPPPPSILIVQAEKRDIESMSLTFSSDPKSLNSSYSNCIFIVSKEQKENPTSYIQEYFDITEFFCQNATIIEADDSELLTKTIESGVGKNDIIFFLVSLEELTIENYKQVTMQYTLVNQILLRNNLSTRFALLTYDSQNGGKNYLGSSLIGTFRYFLEFRSLNIFSIDVDKDSIDNLTLFLRLVDLSTIGDRETIVRNNKIFVQKIFKEPKLLSPSNNYEKNTNNLFLYSNSNLDFSFQSKEKLLHGCVEIKVMSTGINYKDSLFYRGLLPQEVFSKGDIYSPPFGLECAGYITRVAPSGVTRFKVGDQVVGFASHSLSSHVTTHQNKIVLKPENISFNEAAAVCVVYATSYYSIFHIGAFIADKESILVHSATGGVGLASLNLLKWKRNQLKKHGNSEISNDASIYATVGSKEKIDYLQEKYGDLITAIYNSRDTEYCDEIKQQSAQGGVDLILNTLSGDYLSSNFRSLSQVGRIMDLSVTQLVENDSLDFSNFKYHVGYNTIDLDRATKYNSKIIRDILTEVFDAISDGSLENIPVKVFPAIQVKTAIEYINERVHIGKIVVDFENFEQDILKPALQEKENPIQLNKVKKLEHTCDTLNNTILITGQTGIAVHILKWIISGSVLNSNKSQQQVTDFIILSRSSLKWELENLINQTKHKYGDRFRFHYKSVNIADLNSTRTAIDQVYSSCKNVSPIKSVLHFATVYEYILPENITQTVIDNTHNPKAVGAINLHNLSIEKDWKLENFILFSSIGAIIGGSKQCAYSSANLVLDSLSNYRKSIGLASTSINWGGLDAGGVAATDKSVASFLEGQGILLVSLSKILGCLDSVFQPSNSHLSNFMLSSFNIDNLLSSAPQMKRKMDHHLTNYKTSSASSDDSLGDSGSTQAKVISTISELLSIHPSKLNLDTRLKDYGIDSLLTVQLKNWIDKEFTKNLFTHLQLSSSSINSIIQRISSKSTSTSTPNPTNTSKQTATKKT", "length": 2604 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q869Z5-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSHLTPKPNVLNVYGAGTPNFVKVQILLEEKNIPHVYHKIDFSKNEQFDPEFLKFSPNNKIPAIVDNTVEPNGISVFESAAILMYLSEKHQFTDLYADFKTDPALHAKHLEFLFFQMSGVGPMTGQLGWFLRQPEPKNTQAIERYSEEVKRLYRVLDKILSTNTWVAGEQYSIADISLLGWALYFLKGYYDDHITREQFPNVYRWLDLAAKRPAIIKVLETIQPKQK", "length": 227 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86AE3-1", "protein_name": "Probable polyketide synthase 9/36", "gene_name": "pks9", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGNLKNINLKEKGVAIVGIGFRIPSGNNENSISSPDDLFNNLKNGFDGVSSTSERWSDNFHKLGEISSPNAGLLPFKEWKSFDPLFFGINPSEAPLIDPQQRLLLKCTWEALEDASIDPISIRGTNTSVFIGSSTIDYLHTNKHQDSVLKNAIAQSTSAISNRISYCFDFNGPSLSIDTACSSSLNAVSQGYHSILNGTSNMSIVGGVNLILDVDIIKAYSILSMLSKTHGKCKTFDESGDGFTRGECVGVVVLKNLQDAVKDGNRIYCVINGSSSNVDGNGNMDKVNFYSPSKQSQFNNINSAFKSTNDKLSINDIQYIEAHGTGTKTGDPIETEAISMAFKNRDKSTPILIGSIKSNIGHCEAGSGVASLIKCCLMFKYQCFLPNIHFKNPNPLIKFNEWNLKVVTSPIPFNKRNNEKPVSMMINNFGVTGSNCCLLISEFKNNNNFKENINLESQSVNDRVLIPFSANSSNSLNQYQSKFKNIINNQFNFIDFTANQIYSKSNFLYQRSVVIASNSNELFENISNKKQIQTKNSIISNMSFKGKNPITIFVFSGQGSQYPKMALELYNNEVIFKKSIDLIDSKLSKYYGFSVWEKVKTIKDDDLTSIHDPIFAQPALCMISVSLFELYYHWGVNPSFILGHSLGEISASYCSGMIDLDTFCYTVYQRSIAQSKTNGCGRMLSINISDEEFKSMYSQKYPQIEIACYNSPQSIVVAGNESILNEISKELKEKEIFTTMLGSLSSFHTSSQQCTKDSILQLNIESNQPKVPIFSTVTTNLFNESNRFNSQYVYDNIIKPVKFTQTISNIYKHIESNQLNNEIVFIEIAPHPTLLFYIKQMVPSSLNESVSVYSALHKKKNDVEEFQQTISNLYCQNGYNINFKCQFNNKKSNQSINLPLYQWDEELYFTQAQTLEQHRKEGPPIDHLGTSNSYNSPFNNSYRTSIDIKNKPFLYLKGHMVKGKYYFPGCGYIDNIIQLYKNQDIFISFIEFKTPLILIEGINQYLQTNIQQTGKSEYRAQFHFKDQKSNEWIQSSNANFQLLDHGNDIPPKYNIKEIIENKCNLSKLTKNELYTHIKSKTGLNYTGVFQGVTECYIGGDCTLSVVSLESQTNSFLNIPILDTCLHGMIGLSNDQCQIVFDKAIGFKYYSSNIPANLKDYKDSVYVYSHLKSKSVDSFFGSIIVMLSDGSVLYEIEEVVCKSLIPIKDSLKIEYPNDELYKVHLQSKDSPIPTPSSFKSIIYENDFFHSALNIPEDLFKYISTLFYKDIIKRCPEININKINSHSVNEIISSFSKISKHERLFRFVFETIKENGILNSLEENDDAYFEFNEVIIKSSRIISKLLFPLESDNDNEDLPQSLFQNGLMDKIYKCRYLRKKNQMISHVIKHSIKEIINNNIIIRILEFGGGTASLSVEVIEEIIALLQENPNYQVEIEYTWSDISPAFIADAKNKINKIINDAAITNGFNVIYRPLKIDESLIETQSINPSYYDFVIMSNVLHVVKNIKQAVEQMYQLLTPNGQLLFLEPPYKSVLNDSIVGSFEQWWSFTDTDIRKDRCSMSQQSWCQLLKTCNFKDIAMSKECIFVGIVIHAQKPPISLLNSQPKRDNIIIYGGGNPIFVENIKLYSNSKSLIQIETIQEFNQLLSQSTITNDSIIYFIKTLETLSLDNFKQITLEYIEINRKLLQINSLCKHVLIVSDSRKTNYLASSVVGAARYFDEFQQLKLNTLDFDYDSTQNYINSNNKDMVQFINILTDSKTNVHKEMIIINNKVYYEIVQKEKNLKLKYNSESFENQNNLMCSLSPNLEYQLQSKQIKLRDNQVEVKTIATGINYKDYLNFSGSNSNGDDNTGLPQFGYEFSGIITRVGNNVKDYKVGDNVFGLSNSCTSSHIVTNYKKIQIKPSNLSHNEASSIPIDYLTSFMSLFNIGSLNIEDNESILIHLGSDGFGLSTFEILKWKGFNSNLFVTVNSYETKRYLQDNYGDFITGIYSNTDKSYVTEINKKLIKLGSKKKGVDLILNTLPSDFMDSNFKLLAKYGRIIDLTSNHLNQSEFLKNINFKYNHGYHNFELSLIQKNKIHKCLYEISNAFENGELKTIPIKEFTNLNIKDAIKYITNNKIEKITVSHDHEIYSDIIYRSLDEKEFSILKSNYQINSNNLGKNILVTGQSGIILEILKWIIKYSNINTIENVIILSRSSLKWELELLINETKLSNNNIKFHFKSVDIGDSEQVDNAINEILNENQQITNIDSIYHFAFQQITCKVQEINMKHLDISHGAKSMGAINLHNQSIKRNWKLINFVMASSAISLIGSTDLCTYVCANALLDSFSKYRESLGLPSTCICLGAIESTGFVSKNESVSVFLDGGGFHPTPINQVLGLLDLQIQNAGKFTNSMLSNFKPSKFKNNQQTSLFLKFDYLMNLKNNSEETKIENTGNKNIDELFIEKVSELFSMDESKINKNLRLIDYGADSLIIVQLKNWIDKEIGINLITIQQLQNNTISTSMKMILNSLMKNNQNIDDNNKDLPSNRIDYWKNEMKFEESIKPISNEIQSRNNSEKIILLTGTTGFLGGFLLFNMVRLDSCKLIYCLIRNKSKSNNPLDEIINNLKYHQLYEKLNQSQISKIIPIIGDLSMNKLGLSNDDYETISKNVNLIINPGADINQKSSYQDCKLVNVNGVKEIIKLSLSSLKQRIPIVNFSSFSVFFNQSLDKNFDESVLPSIDNIDNLPTEYMKSKVVGEYILLEASKKYNIPSILIRPPSIFLNPETGIGHISDFSLLSIQSCYELGYYPNQFENDFILINTITWLSNNITNIIMNDNCWTDSKMNIYNVHGKQIQSSLIIKPLEKHFNCKHINTNDWIDMVNNSNKKSCIKLKSFHSLDIILKSENNRYKPNENQSISLSTKSLLESMGSYNTDLEITDKMIISHINQIFNLNETI", "length": 2931 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86AF8-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MFSKFSIKENKPKKVKSNSSKGFNNNEINSTNNNNNNNNNNNNNNNDSDNFINNNDSNNNNNFNNNNNNNSNNINNKTEDSNDISLLINQFIGSSPAPSTCSGSDKFSIKPKKIVTPSKRKNSTSGSDIIDFNNCNNNNNSKSNSDSNNNKYNNSNSNNNSCNNTNNGNERKMKGYDYGNNNSNNNYSSSSRDYNSNNNSSPRDYNNNNNNNNNNNNNNNNNSNNNSPRDYNNSRDYNNNNTNNNSSPRDSNSNNNRNSSSRDFSNNNSSPRDYNNSRNSNNSFLNNNNNNNNNSNNSNDNSPRDYNYSSSNSSPRDYNNNNDTFSKKRNNVGNSILEIKSNPTSPRIKPIMVWPRSSPRIVNKLPPVQSLVDLTEIEMIDDNNNNNNNNNNNNNNNNNNNNNNNSNNNNNKSGSNNNFSDSDSDKDNYNNNNNTNNNSFNSDSDNYNNSNNNNSNSNSNSNSNSNSNSNNNNNNNNNSNNNNNNNNNNNSNNSNKSNNNFSNIKILEKRRKSINEISDNLTTRNIEEIDSKMAHEFEHPFLEKLIFAGQRPPFVECDDYFLKRYKNQFQYYLDISMKSIINTRDIGEGDDDDEINSVPFKCTLCSYEYDEENNNENTNGFIDEADKIYNRSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSNSNNNNNNNFYDKKYFKNNYFQHLLSKHLNQIKAKGIQDTNVYNDEANIPLGSKKCDHLECSEIILKNEFTKHIKKLHHHHKDEDIDICPRCKILKKSIQKRIVKFSKKKQEKDDDNNSKPVSNKVATISHNPSPNNIDKDINNNNNNKNNKNNTNNLENDNNDNSSNNNYLENEEEPEIVFQDIKPNNNNNNNNNNNNNDDNNNDNNDNNDNENNNDNNNDNENSNNNNNNS", "length": 901 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86BK9-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 22", "gene_name": "Dmel\\CG32971", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSDSKDEALLKSFKTQLKDNVLSMLLNFEELLKLVSPRTPGQITNDTEQELNAFEMQVRAGNFVRAGEALIKLVHDVKEYQIIYDYSNIEEEMDRQSEAMHAKVTEYDQTLIKMVKDLEEELSELEYEYYEKSGGPDLDSKDLLV", "length": 145 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q86IJ5-1", "protein_name": "Uncharacterized protein DDB_G0272718", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MPPHGHHHHHHGHHGHHEHITITPVYAPPQVVQPIYAPPPVVQPVYVQPPVVYPQATIVLETGHHHGHHHHHGHHGHHDHHHHGHHGHH", "length": 89 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86IV6-1", "protein_name": "DNA replication ATP-dependent helicase/nuclease DNA2", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNFFEKKNNNNNNSSNNNNNNNNNKNNNNKNLDKNNSSDRNNNNNGDKNNLKPTQKSLIDLWFQVDDEDEEYELSSLSNDGGSSFNSFKVNNRDTSIGSDIYSKTITPSSLALSTSSLISSTLTPPTQSPPFSKKNEKTSSFLNSPSSQKSKSNNSNVKEKLSPQYSSSSQLSDFFKKKKRPLLDNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTISSLNTNSNNNSSGSSNGSSSSSSGGGNKSSNNKKQKVSQSTSSTSLKEKQSQQSILSYLNPTPSLPTPIFDKPIERSDSNLATSSFSKLNFDDIPLDDEELSQKINTPSPKLILKNTFSSTPTQKSPSLSSTPPNKIKITDKKLPNSSSSSSSPPPSSAKSKLSHRSQSSPLSPLITNLNQNKSNEFDDINFNFNIPSPLKEINNKPNIKSNSKETLTPLTQIFHSSSPPPSIIIESSPSVCFSPTPTKNQSPTLSNLSPTFSFLSDTSPVKSPSQLFEFTFDDPLSPKLISSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTNTFISKNNLINLFNEQSNQENVSTTTTTTTTTTTSTSTNNNNNNRYERVLIINVFYEVTQIFNNSNDKIHKKTLSGFSESIGESREIQLLDEWIYTPVRPGDIVNVIGEFDDNGEIIINNIQNLLILHPDILITGTELGGSLTCTRRSVLKEQIRVGNSNSSTVPIFGSIVHEIFQECLKNNRFHLDDINTFKQEIIGKSTFQLGLSSLGETQDTALNHLENWLPTIDKFAKTFILPSSSSSSASSLKKNLIEINSEKWHLSISKILEIEENIWSLMYGLKGKIDSSLEIKLVKQQQDEKQSKQSKQSKKKKQQTTSPNNNNNNNNNNNNNNNNNNNNNNNNNNGPTTCYLNVPFEIKTGKPYQIPYISHSSQVLIYTLLMNDRYDQDIEMGILYYLKSQEFKSVGLNYGLLHPILFERNQIRSLIVSRNLLAYFLNLNSQPLLKPNPILPEMLRDYHSCTKCYSIDPCVLYHKAIENGDQFTSSLGDLFLEKTNHLSSIHINYLKNWNKIISLEYSIKNNKRKLIWNKSRKFGEKNNSCIGELILISEEYSEITETFSYRFRVNPDKLLNSSISEGDYLLISVEDKYYGMGSGQLSNIINDIITITCREKLSEPPSLLSDYTTPNCNNNDPSYFGNYRNKPLIYIEYEDADQQQQQQQQQQQQQQQQQQQQQQQSQKQQKQKQPNFTQLRGLNNYVNNSKLTPFKWRVDIDEQLSGLSIVKSNLFNLFLKENQKLRSLIVDLEAPIFDKLEQENYWKSIDFQNDYPLLNIDQRNAIIKTLSAKDYSLIHGMPGTGKTTLVISLIHILWRLGKKVLITSFTHTSLDHLLLKFNKQYPNIEMLRVASSLNQIDPSLHRFTLEKQSFGNITQSKQYLERQQLVATSCLGINHQCLLKMQFDYCIIDEASILSQPISMGPILKCKSFVLVGDHHQLPPIVNNKEAGKLGLDISLFKQLSTSHPSSVSNLYHQYRMCNSIMSLSNHLIYNNRLVCGNQSISNLSLQTNYYHNNNNTTHIDLLDHINNWPQIICNPNSSVIFVNTDQLNNSTESSNGDLFYNQTEANIVAILTNCLINKLNINQSQIGIITPIRFQLNFIKKSILKYLSIENNNNNNNNNNNSNNNNNNSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNQNNNQNYLKKIENLDILTIDKFQGKDKDCIIISFVRSNEKKEIGELIKDWKRMNVAFTRAKKKLIFVGSKSSLSKFPFFLDFFEFLDSKNWIYNLNNKIQF", "length": 1838 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86JI5-1", "protein_name": "Probable polyketide synthase 5", "gene_name": "pks5", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDMKLNDIENENFINQMKGVAIVGIGFRIPSGNSENSISSPDDLFNNLKNGFDGVSSTSERWSDNYHKLGEISSPNAGLLPLNEWKSFDPLFFGINPSDAHHIDPQQRLLLKCTWEALEDASIDPISIRGTNTSVFIGSSTIDYLHANKHPDLILKNAIGFSPSTLSNRISYCFDIHGPSLSIDTACSSSMNAVTQGYHSILNGTSNMSIVGGVNFVIDVETIKGFSYLNMLSKTHGKCKAFDESGDGFTRGECAGVVVLKKLDDAIRDGNRIYCIINGISSNIDGNGIADKANFYSPSKQSQFNNINLAFKSTNGKISVNDIQYIEAHGTGTKTGDPIETEAISMAFKNRDKSTPILIGSIKSNIGHCEAGSGVVSLIKCCLMFKYQCFLPNIHFKNPNPLIKFNEWNLKVVTSPIPFNRNNEKSVSMMINNFGVTGSNCCLLISEFKKQDYESYENNIGSINKNILVPFSANSPKSLDQYQSKIKNIINNQFNFIDFANNQIYSKSNYLYQRSVVIANNSNDLVNKILNKKHIQTKNPIISNMSFKGKNPITIFVFSGQGSQYPKMALELYNNEVIFKKSIDLIDSKLSKYYGYSVLEKLRSIGDDDTTSIHDPTIAQPAMCMFSVSLFELYKHWGVNPSFILGHSLGEIPTSYCSGMIDLDTFCYTVYQRSIAQTKTHGNGRMLSINISDEEFKSMYSQKYPQIEIACYNSPQSIVVAGNESILNEISKELKEKEIFTAMLGSLSSFHTSSQQCTKDSILQLNIESKKSKVPTFSTVTTNLFNESDPFNSQYVYDNIINPVKFTQTISNIYKHIESNQLDNDIVFIEIAPHPTLSFYIKQMVPSSLNESVSVYSALHKKKNDVEEFQQTISNLYCQNGYNINFKCQFNNKKSNQKINLPLYQWDDELYFAQTQVLEQHRKEGPPIDHLGLSNSYYSPFKNSYRTFIDIKNKPFQYLKGHMVKGKYYFPGCGYIDNIIQLYKNQDIFISFIEFKTPLILIEGINQCLQTNIQQTGKSEYRAQFHFKDQKSNEWIQSSNANFQLLDHTIEMPPKYNIEEIIKNKCTLARLTKNEIYTHIKSKTGLNYTAMFQGATECYIGVDCTLSVVSIESQTNSFLNIPILDSVFHGNISLINDQCQIVFDKVHGLKYYSSNIPNDYKDKSVYVYAKLKSKTSDSYSASFTVLLSDGTVVYEIDEAFSKSLIPIKELLKIEYPNDELFSINLQPKDSPIPAPSTFKSLIYENDRFNAEPPMVENLFQYISTIFYKNIINRCPEINIDIIKSLSIDEIISNFSKISKHERLFKYVFETIKENGILNSLEEKDDTYFVFNEVLIKSSRVISKLLFPLENDNDNEDTPQLLFQNGLMDKVYKCRYLKNKNQMIAHIIKHSIKEIINNNIIIRILEFGGGTASLSVEVIEEIVTLLQENPNYQVEIEYTWSDISPAFIVDTKNKINKIIKGAGITNGLNVIYHPLTIDESLVELQSIKPSYYDFVIMSNVLHVVKDIKQAVEQMYQLLIPNGQLLFVEPPYKSIICDSLFGSFEQWWAFTDTDIRKDHCCLSQDGWYKLLKWSNFESIEMSTESKFMGSVIQAQKPSFTSLINQQPKYDNIIIFGNNCPNFIDNIKPFSNFNEFIQIETIQEFDQLINKSTITNDSIIYFIKSINQLSLDNYKQATLEYIEINQKLLQINSLCKHVLIVNDSRKTNYLASSIVGAARYFDEFQQLKLHTLDFDYDSTQNYLISKNNKMVQFINNLIDSKTNVHKEMIIINNKVYYEIVQKEKNLKLKYNSESFEQQDNLMCSLSPNLEYQLQSKQIKLRDNQVEVKTIATGINNKDYLVYSGLEGSVNSNTPQFGYEFSGIITRVGNNVKDYKVGDNVFGLSNSCTSSNIIVNHERIQIKPSNISHIEAASIPIDYLTSFMSLFNVGCLNIEDNESILIHLGSDSFGLSTFEILKWKGFKSNLFVTVNSDEIKQYLLNNYGDLITAIYSNTDKGYVSQIKNKLIEQGSNDNGVDLILNTLPSDFMDSNFQLLAINGRIIDLSNDHLNQSEYMKNVNFTLNRGYHNFDLMSQRNSRINRSLLTISKAIENGELKLIPIKEFSNSDINDAIEFIIEENRIDKIVVSHDHEVYQELYAKFSNENDFSILKSNYQINSNNLGKNILITGQSGIILEILKWIIKYSNINTIENVIILSRSSLKWELELLINQTKLSNNNIKFHFKSVDVGDSEQVDNAINEILNENQEIINIHSIFHFAFTQIACKVQEINMKHLDISHGAKTMGAINLHNQSIKRNWKLINFVISSSIASLVGSTDQCSYVCANALLDSFSKYRVSLGLPSTSINLGAIESTGFVSKNESISVFLDGSGIIPTPINQVLGLLDLQIQNPGKFTNSMVAKFNPLNFSNNEQINLLLKMDYIFNLHSNGYTKVKESAGSKNVDELFIKKISDLFSIDESKINKDIRLIDYGADSLVIVQLKNWVDQEIGFNLITIQQLQNNTINVSIKIILNFLKKINK", "length": 2512 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86KS1-1", "protein_name": "DNA cross-link repair 1 protein", "gene_name": "dclre1", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSDDEDDINLYITRSKNNENKKTNKNRLIDNNIQKTKTTTAVLTTRTTTTTTTTTASTQLKWDYGDEDDDDYSAPKDIDEEQSSKQFNYQNNQIVVKQDHDDYSAPKDMDEEQSSRQFNYQNDQTLVKQDDDHDDYNEPKDIDSQSLIDEDCDFEFDNSDFFFDDGTTNNNDNNNKNNKNNNNNNNNNNNNNNYNNNNNKNYKRKYYQSYNNSNNINNNNNNNNDKFEKRLSDLKKTGKEEAKKRGYQVRKTPTKEKKIPPSFKVIDGTNFLVDGFQYKSEDFTHYFLTHFHSDHYVGITKTWSFGNIYCTEETGKLVSHKLGVDQRYIVKCEWNKLIEIQGVKVAFLDSNHCPGSALILFIIPLRNKDGEIIGEESILHTGDFRYNQSMNNYPLLKGRTISKLYLDNTYCDPQYVFPPQPEIIKQVASIVRKENDGETLFLFGTYVIGKERILLEIAKQEGKPVHVSNEKYAILCCLSTCLDINKFTTNELITPFRAVTMSMLSYHNMLSLLDSSNNKYKRVIGFRPTGWTQAKKSITYLNRGPTTFYSVAYSEHSSFNELRDCIDHFRPTQIIPTVDCDSPIKVKNILAHFSDLYEKKKQLTIASFFSAQPVTNFFQSFFKSKSEPIIDEDNKKLIPITTTTTTNINTLTATDTTTTKIKTSNTLIKDEFTDDLIWDCSDDLISDRKLLTQSDNSSALCKIEKEENFNDLSENNNNSNNNNNNNNNNNNNNNNNNNNNNNNNKLIIENDIKEEIIDFDDPVFISQQKWIEKQIYNNNNNSNNNNFTTPTKTNGNLSNNAKLNLTPTQTQTQTPTQNNKKQKTTNVSPTSYNSNNSSQQSGLKRSKSDPNVKKNQLQTSQPPSQSLITSFFQKCASPTSLFSATPPTPSITTTSNQSTKNKNSTTTTSTSTSNNKPFKN", "length": 920 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86KX6-1", "protein_name": "TNF receptor-associated factor family protein DDB_G0272348", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEFELEDITIEQSSFTNNNSNNNNNNNNNSNSNNNNNNNNNNINNNNNHNNNNKNNSNNKNEINNQLDIPISNLVVDKENISKKYFCTICSDLLVNSFHADKFKAVQCKNGHYTTCLNCWEKHLEKKKNCIQCGVDVESIESLSSNLLVTQKFTTFKIHCPNSFFDTIDFIKDEVNGCKEIIQINELEEHLKECQYGFISCKNCEEFSKLPFQEFTQCPDFRKNTKEQHDLICPYVKISCEYCGDIINKINKESHNANWCQEITIKCLDCHLPFKKKEINQHQKSFCPETIIQCRYSKGGCNAMIRRSKLSQHLTEGDNHHQFISNILNQQDLKINELELKNTEFCLLLNGQNKKITELEILFKELNDSILIQKQQQKQQQQQQQQQQQQQQQQQQQQQSQQQQSQQQQQSQQQQQSQQSQQNNNSNSHFINNNNNNINNVQMSDSPNGGSLPQAVYKNKWVISNYSEQEQQGISKDYIKSPLFKIGNSTFFLKWFPFGKKKLNYCSIFLYKTQDDKSIIVNYYIHLVNNQISDEVYEKRGCQKYDSENGSAGYGSSQFIKRADLLNDANGFLINDSITIEIEIFATEEILPLQS", "length": 595 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8BI41-1", "protein_name": "Syncytin-B", "gene_name": "Synb", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTGFWVLCFVLFPSSLSYPESWMPLVNLTHHILRDTNSSLFSNCWVCLSTQTQRSLAVPAPLSIWTDTPMKLHLTYSVRPFSGSFSISDIERRLRLFRPLTASYSFHNPDRRAIAFLQLVSSTGIFRIITRITSVIYPHKDRFFESAQRPLWGPLFTETVLRSQAPLCISRFFKVSAYATFVGNLSASLCNYTMHISPSTSHENLDLSTTHTFKQAMKRPDAKWKNPLRFSGPPSLIFSKPAYYPCPTDIKHCHTSPATPWMHCPQAPFGTCYNLTLFEPDNSTHPVTMSVNPTHFKVKLQGHRDPYPLSHYQPLTGAALSGQYSVWENEITVQENWDITSNIFSHLLSFSYAFCLNSSGVFFLCGTSTYICLPANWSGVCTLVFQYPDIELLPNNQTVPVPLFASVLSSDSVLRPKRSPHLFPFLAGLGISSALGTGIAGLATSTLYFQQLSKVLSETLEEIAASITTLQNQIDSLAGVVLQNRRALDLITAEKGGTCLFLQEECCFYVNQSGIVRDAARKLQERASELGQHSDSWGQWPDLGRWLPWLTPFLGPLLFLFFLLTFGSCLLNCLTRFVSQRLGSFVQDTAKRHVDSILQNFQYKKLPQDSPDEDTIPT", "length": 618 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8BYG0-1", "protein_name": "Tetratricopeptide repeat protein 24", "gene_name": "Ttc24", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSSRQYGLSDVLRALEESRKLADADRSTDQGLLGPFYNDLGMGYFQLQLFPLAVEAFLQALPLCRQPSEQATVLQNLGMTHNVLGNYWEAQEFHQKAASLHGSVGQRWEQGRSFSGLAFSLSQLGDHRAAWDSYLHALQAAQDTGDVKGQWQACEGLGAAAARLGQHDQALKYYKEALALCQHEPSSVRERLVAKLADAMRTFVAQEKIAQARFLPSAPGKLQTSRKAKTSARVQSSAEDAQESQWEGEASEGGHEKKEMEGLVNTATVLGPQRQNRATTHLPSGGPSPSGEEYPFIIAPKKLRVSRSSTWAKEALGRNFQRTRIQSGLCSIM", "length": 334 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8C1N8-1", "protein_name": "Alpha-defensin 22", "gene_name": "Defa22", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKKLVLLSALVLLAYQVQTDPIQNTDEETNTEEQPGEEDQAVSVSFGGQEGSALHEKLSRDLICLCRKRRCNRGELFYGTCAGPFLRCCRRRR", "length": 93 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8C1P2-1", "protein_name": "Alpha-defensin 21", "gene_name": "Defa21", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTLVLLSALILLAYQVQTDPIQNTDEETNTEEQPGEDDQAVSVSFGGQEGSALHEKLSRDLICLCRNRRCNRGELFYGTCAGPFLRCCRRRR", "length": 93 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8C5Y2-1", "protein_name": "Mitochondrial sheath formation-associated protein", "gene_name": "Misfa", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIVLGWMLFVGLATYMGTFPEAMPPTLKWKERLPGQENKARRRIQALEEELLL", "length": 53 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8CDW1-1", "protein_name": "Protein FAM228A", "gene_name": "Fam228a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADTKTSKCDEHFSVEKLKEWPEPESVSLMELLAREDIDEAVHAVLFRENYVVKRLDTYLQHLAVFKERRKEMLHKKWVENVVQPLQQRITDKITSYRRPGKNQVKYEHCLKQTNKPTKVSSSCLFQKQQEFREAKGTSYQHGRGKTHDTQKEAKETEKGLSFTPFSLRPHCSSPRERQRASARLMQSKPGGRNRYKGASSEKPVFTLKSHLPKEEKTVSRSQLVFERQFRASRLSQDIKEAEKKGLVVGTGPQRPRSWAAADSVPRPSLVGRRVMTAEILGEHLVSLHQAARSGLQWP", "length": 299 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8CEK3-1", "protein_name": "Serine protease inhibitor kazal-like protein, minor form", "gene_name": "Spinkl", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSTWIKFLFILTLVLLPYSVFSVNIFAGPENVIKEPNCTMYKSKSECSNIAENPVCADDRNTYYNECYFCIEKVVEKLKYRYHGICIYK", "length": 90 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8IZP1-1", "protein_name": "TBC1 domain family member 3", "gene_name": "TBC1D3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPLTAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNTEEMKLKNPGRYQIMKEKGKRSSEHIQRIDRDVSGTLRKHIFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQEHVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPITRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKKGDLPPPAKPEQGSSASRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGAVREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWVRAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHLESSQFPPGF", "length": 549 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8K072-1", "protein_name": "Receptor expression-enhancing protein 4", "gene_name": "Reep4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVSWMICRLVVLIFGMLYPAYASYKAVKSKNIREYVRWMMYWIVFAIFMAAETFTDIFISWFPFYYEFKMAFVLWLLSPYTKGASLLYRKFVHPSLSRHEKEIDACIVQAKERSYETMLSFGKRSLNIAASAAVQAATKSQGALAGRLRSFSMQDLRSIPDTPVPTYQDPLYLEDQVPRRRPPIGYRPGGLQGSDTEDECWSDNEIVPQPPVRPREKPLGRSQSLRVVKRKPLTREGTSRSLKVRTRKKAMPSDMDS", "length": 257 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8MP30-1", "protein_name": "Uncharacterized histidine-rich protein DDB_G0274557", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEIKYFLVLLVGFLLVLPSIVNPYRKGVTITNQQPKINIYQLDVNNPHNPNNNPHNPHNPNNNPHHPHHLHHHHHHHHHHHHHHHHHHHHHHHHHHPHHPHHHPHHHHHPHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHPHHHPHPHPHPHPHPHLHPNPHPHPHPHPHPHPHPHHHPNPNPHPHPHPHPHHHHHHQEASECLSYQGNRNRLFIKRDY", "length": 233 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8NG83-1", "protein_name": "Olfactory receptor 2M3", "gene_name": "OR2M3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MARENSTFNSDFILLGIFNHSPTHTFLFFLVLAIFSVAFMGNSVMVLLIYLDTQLHTPMYLLLSQLSLMDLMLICTTVPKMAFNYLSGSKSISMAGCATQIFFYTSLLGSECFLLAVMAYDRYTAICHPLRYTNLMSPKICGLMTAFSWILGSTDGIIDVVATFSFSYCGSREIAHFFCDFPSLLILSCSDTSIFEKILFICCIVMIVFPVAIIIASYARVILAVIHMGSGEGRRKAFTTCSSHLLVVGMYYGAALFMYIRPTSDRSPTQDKMVSVFYTILTPMLNPLIYSLRNKEVTRAFMKILGKGKSGE", "length": 312 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8NGV6-1", "protein_name": "Olfactory receptor 5H6", "gene_name": "OR5H6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MFLYLCFIFQRTCSEEMEEENATLLTEFVLTGFLHQPDCKIPLFLAFLVIYLITIMGNLGLIVLIWKDPHLHIPMYLFLGSLAFVDASLSSTVTPKMLINFLAKSKMISLSECMVQFFSLVTTVTTECFLLATMAYDRYVAICKALLYPVIMTNELCIQLLVLSFIGGLLHALIHEAFSFRLTFCNSNIIQHFYCDIIPLLKISCTDSSINFLMVFIFAGSVQVFTIGTILISYTIILFTILEKKSIKGIRKAVSTCGAHLLSVSLYYGPLTFKYLGSASPQADDQDMMESLFYTVIVPLLNPMIYSLRNKQVIASFTKMFKSNV", "length": 325 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8R264-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r215", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNWNNIIHTIIFLSLTGPGIVGNMLIFIRHIYMPALGTEKKPVDLIVIHLAFSNMITICTTGIKDIATVFYFRNFLGDIGCKAVVFLARMARGLSICTTCLLSVVQAITISPRTSLWTKLKPQTACQIIPFILVFWIFNGLISSNLLSYIKGGSSLNRSVAATFIGHCYMLQSRHTIKWIFLSLMTLRDVIFQSLMGWSSGSMALNLYKHHKRVLYLYSSRFANNSPPEIRATWSVLILMTCFLLFYWADFILSFYHGFTVTHESILLNIKVFLELGYVSFSPYVLISRYIHPPNVFHAH", "length": 300 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R272-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r220", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVLQFIKKTIFLFMTMVGILGNMSVSVHYMFSWWGSPEKKPIHLILTHLTFTNIILLLAKGLQKTIIVFGLRNFLDDIGCKIIVYLERVARGLSICTSSVLTVVQAIIISPRASGWRRLRPKSAWHILPFFSFFWILNAFISVNLIHSIRSKGMNTSQHKNSDDYCYLTPESQKIKWIVLPLMVLRDAVFQGAMGGASGYMVFLLHKHHQHVLYLQNSKLLYRTPPELRAAQSVLLLMLCFLFFYWTDCALSLFLSLSLGDSSLMINIQGFLTLGYAIFSPFVLIQRDGLIPVCWHAQ", "length": 298 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R278-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r213", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLALRNYIQINTPWCMCLFVTPLTPCLPEYWDPDSLRVEGPTESSLRHNTASCTLKNTIMQNVQFRSMSSITDAFFKMYLHTRKEEMILKILKEITFLIMTVLGILGNMSVSVNYMFSWWGSPEKKPIHLILIHLIFTNIIILLVKGLPKTIAAFGLRNFLDDIGCKIIVYMERLARGLSICTSSLLTVVQAIIISPRASGWRRLRLKSAWHILLFFLFFWILNALISVNLIHSTTNTRLNVSQLKSDDNYCYFMLPIQKIKWIVLPLMVVRDAVFQGAMGGASGYVAFLLHKHHQHVLYFQNSKLLYRTPPELRAAQSVLLLMLCFVFFYWTDCAFSLFLTLSSEVNILMVNTRDFLTLGYATFSPFVLIHRDGLLVECRHVQ", "length": 384 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R2A9-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r229", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDFGNLAMGIVLSLQSALGILGNFSLLFYYLVLYNKERTLKIIDIILIHVFTSNSLIIFSKGLPEVLAVFGWNDLFDDVGCKLIMYVRRVSRSMSISMTCLLSVFQAITISTRNSCWKEFKEQTAKFMGLFISLCWILFMLVNMLFPVYTSTNRNSKNKTQKKDIEFCHSVGRDKMVDIMYTAFCVFPEVLFSLLIVSSSTTMIVILYGHKKRVQHILHTHASPRTSAENRATQTILILVCTFLAFYTLSSVLQGYVALSHDPSWWVMNITTIISMGFPAIGPFVMSRDFTVSRFCFTCIGNLKLP", "length": 306 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R2B6-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r178", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHDKSLKTTDDMTLQILLLCQFVVGTVANVFLFLHNISPVLTGSKQRPRQLILSHMSVANALILFLTSFPDMMAFAPRNSPTHLKCKLEYFSRLVARSTNMCSTCVLSIHQFVTLVPVNRGKAILRASVPNLTSYSCYSCWFFSVLSNIYIAIKVTGPQITDNNTDSKSKLFCFTSGFSVGIFFLRIFHDGTFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNFICIIFYTFSIDSRLFMSHFSKVFAAGFPTISPLLLIFRDPKYPCSVLFNC", "length": 304 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R2B8-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r64", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSQNKTLKTMEVLALQILLLCQVVVGTVGNIFLFVHNFSPVLTDSRLRPIQVILINLAVANAFMLLLFAYSYDLIDFVPRKPPTDLKCKLAYFFNMVAQGTIMCSTCLLSTYQFVTLVPGNWARVMFREISPKVVSYCCYSCWLFSVLNNAYMPMYVSGPQKTHNDSDSKDNWICSISGVSVDMNFLRFSHDIIFIGIMAWTSVSMVIHLNRHHHRMHYLHNPNQINRGHAETKAAHTIMMLVVTFVSLYILDCICSLFHISFVESRLWLIDVIELLHLSFPTVSPFLLICRDPMGPCSLLFIVGLEIHVTVGAITEEQ", "length": 320 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R2B9-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r59", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEMLALQILLLCQVVVGTVGNILLFVHNFSPVLTDSRLRPIQVILINLAVANAFMLLLLTYSHDMIDFVPRKPPTDLKCKLAYFFHMVAQGTIMCSTCVLSTYQFVTVVPGTWARVMFREISPKVVSYSCFSCWLFSVLHNAYIPMNVSGPQKTHNDSDSKGNSICSISGVNVDMHFLRFSHDIIFLGIMAWTSVSMMIHLNRHHQRMNRIHKVNQNNRGHAETRAAHTILMLVVTFVSLYILNCISILFHISFVESRLWSRHVIKVLALSFPTISPLLLIFRDPRGHCSLLFSVGLEIHVTGGVITEEQ", "length": 310 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R2C0-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r62", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEVLALQILLLCHVVVGTVGNILLFVHNFSPILTDSRLRPIQVILINLAVANAFMLLLFAYSYDLTDIVPRKPPTDLKCKLAYFFHLVARGTIMCSTCVLSTYQFVTLVPGTWARVMFSEISPKVVSYCCYSCWLFSVLNNAYMLMNVSGPQKSHNDSDSKSNSICSISGVSVDMNILRFSHDIIFLSIMAWTSVSMVIHLHRHHQRMNHIHKVNQNNRGHAETRAAHTILMLVVTFVSLYILNCISILFYISFVESRLWLRYVTKLLALSFPTISPLLLIFRDSKGHCSLHIMSVWKST", "length": 300 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R4R9-1", "protein_name": "Protein phosphatase 1 regulatory subunit 14C", "gene_name": "Ppp1r14c", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSVVTGGGEAAGGTSGGGARVFFQSPRGGTGGSRESSSHSGSSREDSAPVATVAAAGQVQQQQRRHQQGKVTVKYDRKELRKRLVLEEWIVEQLGQLYGCEEEEMPDVEIDIDDLLDADSEEERASKLQEALVDCYKPTEEFIRELLSRIRGMRKLSPPQKKSV", "length": 164 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8R4V1-1", "protein_name": "NFAT activation molecule 1", "gene_name": "Nfam1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESWLLRRGARVRCLHPPSWLPAWCFLCLLPVPQTLQLTGLVSLTHTSLPIMVSLANTDVFFSCRIEDFTRLQRDLPVKLFHTDIHGRRRWEKQINCQHRPGMENHTRDCMVKLSQANTSATGIYYFIVEGEETYQSDGVVILVRDTVYQPPAFKVQEALMLGFTSLMSVLGVLGTALLLWKKKQISVLGKHTAKTCSGLKSTVGTTKPPAESVYTSLQRRETEVYACMKEETGSPVFSQSPATKEKLNRFEDDNEFNLVYENL", "length": 264 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8T277-1", "protein_name": "5'-AMP-activated protein kinase subunit gamma", "gene_name": "prkag", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MWYPGDEDEEFTSIIENIEKKETQEIKIKTEKLRQASLNQLPIEQSEGVGGGELSEYNNNTTNNNTPTNTTTTTNTNTTTMNNSNNNNERILSTSNGFDIRLPPNSIEQPSPSFISSSQDGVLTVDPLAVDGEKGNKESQSPPNGDNQILNNNNMFFKDITSLPSTDNKSSTNTNNNNNENPLKQTISSSPSKSTTTTTTSTSTTTTPSLSSLSSNNNNNSNSNNNYINHSSISTVSEGLENLNLKSGIKKIDSETEKYIEEGKQVFVNFLKGHTCYDVIPISGKVVVLDTKLAVKSAFYALEENGIKSAPLWNSEQHDFTGMITVSDFIDILLYYYKKPKSNNIFQDMGIHRIETFWREISVERPSSLISTEPETNLYDAASLLLCYKIHRLPVVDKKDTNSILHILTHSRILAFMMKSFPQLPEKLLSIPIGSLGIGTFATVVTVMTHTPLVEVLELLSEKKISAVPIIDSETSKIVDVYSKSDVTLMSKQGILSPSDLNLPVHQVLSTFTKLWQRPEQIYTCTRFDKLGDVIERCIKKRVHRLVCIDSSKKVEGILSLSDILNYLLNDVKSINH", "length": 577 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8VEU4-1", "protein_name": "Olfactory receptor", "gene_name": "Or14j2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIVENITTMRGFLLMGFSDNHELQILQALLFLVTYLLGSAGNVIIITITTLDPQLQSPMYYFLKHLSILDLSSLSVTVPQYVDICLTQSGYISYAQCMLQIFFFTGFAWGEVAILTVMSYDRYVAVCLPLHYEVIMGPSKCRWAVTAVWLSSVIPGTLYIASIFSIRFCGDRIIHQFFCDVPQVLKFSCSDDYLVTVGVADFLSAVAFACFIGIVNSYVHIFSTVLRMPSAESRSKVFSTCLPHLFVVLLFLSTGIFAYLNPTSDSPTALQFLVSIFYTVLPPTLNPVIYSLRNETIKSVIRKLLLSSKFTG", "length": 312 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8VFX0-1", "protein_name": "Olfactory receptor", "gene_name": "Or5b101", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MENRTEVRCFILVGLTNDPSLQLPLSITFLLIYIITLIGNLGLILMILLDSRLHTPMYIFLGNLSLVDFCYSSTVTPKVIAGFLTGDKIMSYNACASQMFFFANFGDVENYLLASMAYDRYVAVCKPLHYATTMTTHMCASLVIGCYICGFLSASIYTMDALSLSFCESNVIHHFFCDVLAVMIVSCSDSHVNELILIYVVSFNMFFALIIILISYMFIFTNILKIHSSAGYHKAVSTCASHFTAVSIFYGTIIFMYLQPSSSHTMDTDKIASVFYTMVICMLNPLVYSLRSKDVKSAFTKIVLRSK", "length": 307 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8VY69-1", "protein_name": "Vesicle-associated membrane protein 723", "gene_name": "VAMP723", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAQQSLFYSFIARGTVILVEFTDFKGNFTSVAAQYLENLPSSNNKFTYNCDGHTFNDLVENGFTYCVVAVDSAGREIPMAFLERVKEDFYKRYGGEKAATDQANSLNKEFGSNLKEHMQYCMDHPDEISNLAKAKAQVSEVKSLMMENIEKVLARGVICEMLGSSESQPQAFYIKRTQMKRKKWFQNMKIKLIVLAIIIALILIIILSVCGGFNCGK", "length": 217 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q8VZ67-1", "protein_name": "Uncharacterized zinc finger CCHC domain-containing protein At4g19190", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDGEGEGSGIRLSKRFAGGKVTGGSLEVDYKTKSGTAWSHSFLNQKPWHPLSYPNQRRKWIAEQTHAQHDRRAEEVAREFAQEQEFFKQAALISKKEREKIETMKAVSFMYVRPPGYDPESAKAAEYKDEKHKGQGSSTQDPVADDNVGSRPEESQGGGERTQERKKPRPKDVFGRALPTEEEFEVLKNAPRMETGIPGRVKPFAVEVRNVKCLRCGNFGHQSGDRDCPLKDAVMPNEELRLKRDDPLTAIIAHTDPSEPLKWELKQKPGLSPPRGGFDPDDPNQQIVAEDIFDEYGGFLEGSIPIEILKSMSSDKKRKSKKNKRHKKHSSRTVEETDESSTGSEDSREKRGSKKRKKLKKKSKKQYDSDSLSFEGSGSDSYRLSRRRHTKHVDPSASLKSEVYHQGNSHREKHYYDEKHQKRKEIVDRPSASSDDSDYYRSNSSRKKRSEDDYKSHHRERKQVHSNDPVSEKSQKQHYSESGKIQRVEKEHRYDERRHRYVDMESENRNRSEKKPRYDDRDSEKHHRSVKGKEKHVYEASDDPEEFSDRYRSTKKTESDSESNRRSRKKKHELSSEEEEGESRKHRYSTNRRRN", "length": 595 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q91V82-1", "protein_name": "Beta-defensin 8", "gene_name": "Defb8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRIHYLLFTFLLVLLSPLAAFSQKINEPVSCIRNGGICQYRCIGLRHKIGTCGSPFKCCK", "length": 60 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q923B3-1", "protein_name": "Neurotrophin receptor-interacting factor 1", "gene_name": "Nrif1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASTLPTTWPHESVKFEDVSLTFTEEEWAQLDFQQKCLYREIMMENYSNMISVEHHFSKPNVISQLEKAEDCWPMQREIPQDTLPECSWPSPDPGMNSFPSKSPLMKIEVVEVLTLNKDVAGPRNALIQSLYPEDLNPGNLKPAQQPSKRLTDTEASRQKFRHFQYEESAGPQKAMSQLRKLCHQWLQPNTRSKKQILELLVLEQFLNALPEKFRVWVESQHPEDCKAVVALLENMTSVSKDDASLACSSEATDQLKEKRKGVATLPVTFAAEVPAEEPVTFQDVAVDFNEEEWRLLGPTQKTEYHDVMLETLGNLVSVGWEPTLGNRELTPDSPIPVVKPIHDPNTNDLSRNGTQSTVFESILEDGVKEMHSIESNQVGNLQEKGHPQKKFSESSKSQDQTSRHKSQGSLNEVLPRKYVKVKQKGTGKRKGRTNTISMTRGLRIRKQQKDSVEWQGRSGSTPVTHGSSIKKQQQGSEQGKPGTSRDPITLTVPAKVYQKATGSEESIFMDSSDAMVPDVPPKIHQKGPEWHKVGESNNSMLQGSSVQNHQMESGAGRASDNSLLTHALPVKSHQKGYKEGNVQGNRNSWKHIKPHQKGSKGERVEELSTSEKHVPYVKNHLKTSERGKDREINASIKCDPYIKTYYRGSDVGRLRRANNCRKAFSLHAQQISFIKIHKGSQVCRCSECGKLFRNARYFSVHKKIHTGERPYMCMACGKAFVQSSSLTQHLRIHSGERPFECSECGRTFNDRSAISQHLRTHTGAKPYHCERCGKAFRQSSHLTRHERTHTGERPYVCIKCGKAFTQSSHLIGHQKTHGIKFKKQPKL", "length": 828 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q924S2-1", "protein_name": "Inactive 2'-5' oligoadenylate synthetase 1C", "gene_name": "Oas1c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MENGLCSIQARELDEFICDYLFPDTTFLTELRADIDSISAFLKERCFQGAAHPVRVSRVVMGGSYDEHTALKGKSEAKMVLFFNNLTSFEEQLKRRGEFVEEIQKHLCQLQQEKPFKVKFEVQSSEEPNSRSLSFKLSSPELQQEVEFDVQPAYDVLYELRNNTYAEPQFYNKVYAQLIHECTTLEKEGDFSICFTDLHQNFMRYRAPKLWNLIRLVKHWYQLCKEKLREPLPPQYALELLTVYVWEHSNKNQEKVTTAKNFRTFLELVAYYKNLRIYWTWYYDFRHQEVCAYLCRQLKKARPLILDPADPTRNVAGSDLQAWDLLAKEAQTWMQSSCFRNCDMSFVPTWDLSPERQECAFQ", "length": 362 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q925U0-1", "protein_name": "Oocyte-secreted protein 1", "gene_name": "Oosp1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKPFVGLLGLLLLLSFMKTCADDWTAISLQCADHWFHLRIRPTIFHNIFMEPDEVFLGIGCPVTTTWPNDTYEFIYRTYSCGIANKVLCDVTLLKTQLTYISKNASLQAEMSLSCVMHNQSPHFCEAESRGDFTGDPPGWTEDMRARRDEQTVPMVQPNLSTSSEDHHVSTEPWASETSRSEAAEVPSFMDQNFSVFHFSRM", "length": 202 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q94490-1", "protein_name": "Ubiquitin conjugating enzyme E2 B", "gene_name": "ubcB", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MAAHKRLQKEITDMLKTPPSWCSAHLVDDNLQKWKATVQGPEGSPFEKGVFSMDIDIPADYPFKPPTLKFTTKIYHPNIKTSDGAICAEVFSTWSPQLKILDVLTTIRSILTDPNPDNPLETEIAQQFKTDRNAFNKTAKEWTKKYAK", "length": 148 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q945S5-1", "protein_name": "Vacuolar cation/proton exchanger 4", "gene_name": "CAX4", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSSISTESSSNLSLLENGGGGSDKPTAETSRRVRRTVSASSLIRKRSDLKLISRVRWEFMRRILTNLQEVLLGTKLFILFPAVPLAVVAHRYDCPRAWVFALSLLGLTPLAERISFLTEQIAFHTGPTVGGLMNATCGNATEMIIAILAVGQRKMRIVKLSLLGSILSNLLFVLGTSLFLGGISNLRKHQSFDPRQGDMNSMLLYLALLCQTLPMIMRFTMEAEEYDGSDVVVLSRASSFVMLIAYLAFLIFHLFSSHLSPPPPPLPQREDVHDDDVSDKEEEGAVIGMWSAIFWLIIMTLLVALLSDYLVSTIQDAADSWGLSVGFIGIILLPIVGNAAEHAGAVIFAFRNKLDITLGIALGSATQIALFVVPVTVLVAWTMGIEMDLNFNLLETACFALSILVTSLVLQDGTSNYMKGLVLLLCYVVIAACFFVSNSPSSKLLF", "length": 446 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q96AK3-1", "protein_name": "DNA dC->dU-editing enzyme APOBEC-3D", "gene_name": "APOBEC3D", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNPQIRNPMERMYRDTFYDNFENEPILYGRSYTWLCYEVKIKRGRSNLLWDTGVFRGPVLPKRQSNHRQEVYFRFENHAEMCFLSWFCGNRLPANRRFQITWFVSWNPCLPCVVKVTKFLAEHPNVTLTISAARLYYYRDRDWRWVLLRLHKAGARVKIMDYEDFAYCWENFVCNEGQPFMPWYKFDDNYASLHRTLKEILRNPMEAMYPHIFYFHFKNLLKACGRNESWLCFTMEVTKHHSAVFRKRGVFRNQVDPETHCHAERCFLSWFCDDILSPNTNYEVTWYTSWSPCPECAGEVAEFLARHSNVNLTIFTARLCYFWDTDYQEGLCSLSQEGASVKIMGYKDFVSCWKNFVYSDDEPFKPWKGLQTNFRLLKRRLREILQ", "length": 386 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q99N64-1", "protein_name": "Germ cell-less protein-like 2", "gene_name": "Gmcl2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9C7P4-1", "protein_name": "Putative zinc finger CCCH domain-containing protein 9", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MADAGDNQQEAERRSDETESRSIKEPKEKEDEDENPQDQIQSKERMRQSSPYPVRPGKKDCQFYLKNGLCRYRSSCRFNHPTQRPQELPVRICKHIMDRNVAEPMYQDWRESESERRFDERTQRTFGDERTQRRYGIEYSGARPEKRSKIVPDFQMRDPRHHDTEWRFERERMERIERQRREAEENLQEQRQRDSIERQRREAEENLQEQRQRDSIERQRREAQENLQQQRQRDSIERQRREAQENLQQQRLQDMPENHNVDDQQNLQEQRRISIEKERTEARLRLEQIRPTVSFPINEFIRAVVLLRELIENWDDKAWKK", "length": 321 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9C8M4-1", "protein_name": "DNA-directed RNA polymerase subunit 12-like protein", "gene_name": "NRPB12L", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDLQQSETDDKQPEQLVIYVCGDCGQENILKRGDVFQCRDCGFRILYKKRILDKKETRIGV", "length": 61 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9CQK8-1", "protein_name": "Small proline-rich protein 2A1", "gene_name": "Sprr2a1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSYYQQQCNQPCRPPPVCPPPKCPEPCPPQVWPGPCRPVMCFEPCLPSVWPGPCRPVVCYEQCPPQPWQSTCPPVQFPPCQQK", "length": 83 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9CWP4-1", "protein_name": "Lymphocyte antigen 6K", "gene_name": "Ly6k", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAFLVALLVVLGLQLVQSNALTCHVCEAQNSYACSNPSQCPGEKKFCLLAVTRIFERFFYVSKQCTRRCPTPVVSPPSTNPPSEPKEFLIEKPMPFLFYKCCQWDSCNGEGPPTDQLLKEQPGKASGRRHRYIELLLTGFMVLTANGLSALCLL", "length": 154 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9D541-1", "protein_name": "Coiled-coil domain-containing protein 7A", "gene_name": "Ccdc7a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKCAKHPSTISMKLTSVPELPYKKGLLNSSPKPKEKHNAKSKYGKNESMVLRSPPTGESIVRFALPIPLSKTKDKISADEMVRRITTNLKMVVSNLEDTYGACYDNGEKAAEKSEAEGLSIGDDVSSFLLCCSQFTSQLEEAVKEECGALESLYKWFQQQVNQMEEISKDQSNLEELQSDGKTASLNIVQIAKLARKFEDFKSRLKTRKEVMQTKNEDKEIMAETLKHYGLMEKQIEEFITSHSALESQTETESQSGTPSVTTRMARMIKIFENQSTMLEKALNDQQTIESKYKQLETDFQMLIMEKTLLEAEIRRLREIERVKSAAKEEQTKKSGKSEKKKFKEKEKNLSPNREFKSIEELLQIQKEAELLKTEKKTLQGQLKWALEEAERNKTQLEFVLHQKMEMFKEESKTKVGQSQNKSKVKIEDSKDSLPKKSDTQLGGQRKDQISSDQSKRPKKKQLADIDPSAVEDFPPETFKSFTVMPLIEEHRESISSQPKEEMAKASEQSEAEDIEGPLEIPSESSNEDDDLLPEDESPMMEQVTDVGRYKSIYISAEPIDTMSLISRTQSEMETLEAINYDNVLNEGEEQDKKIGKDSDTGRKSKRKRSSKIRKLSTHEEESDIVHYEEATKAKVPSKKRASDPYGDEAYESRGSVSKAQTYTKKQGTHQRGRGSASDAYGDEAYESRGSISKAQTYTRKQGTHQRGRGSVQEEESDTVHYEEVTRAKVPSKKQASDPYGDEAYESQGSVSKAHTHTKKQGTHQRGRGSVHEEESDTMNYEVPRKSKISSRRKGFALPITHQVEMHSSESQGSISKSNTETKKQGTHKRGRDSDADGARTPVSQGSDSKADTERKKHRSKEESTISKDSIPVLDEVQDKTFEHQESGLRLEVQAKKLTFSSQNIHNEESATDIKVEYQNVPSSSQVQLKKQKPLGGEIFTTHFVVPAESHAQLYQTHTPETQIERGTTSGTARLTTIPVEHPKKEASPDNLFPEKKLYITRAPTQTKKQYPPWDAKAETQKKTVKEVQGISEPQTKLNPTMSGIILHLDMDRVVETDLENLEETIVPHVLRSELEIGTDAKNMPETPTSREAVRTEAKGNQDVTISIAKGMKLIGKLKDQHGLSSFASKDTISPGKSLIKSSRDNQDDSLLETKPQENTSDKYHPSKTFPTKVINMLPFSEKSLGSTSANVDVAPKPVYRASRGRSRISKALQQLLKTSEHLKPTSTKNQNADLEKHLYISVRSANKHTQKDKKHGQSNNQKLKKQGALSSTKKQKHKEQPKTETIVENNDKFDDNLMMTTSSPNIKIIKELSKTLNLDGGDIELSDFVFKTASAAKKLENKGPSKTKNLNKESSRDIHILHLTTSAIRTLLLDEEAKIRSLEKKLMKQSTILQKSVSSMKKFMFEEPSRETKMKRKKREKRKIVVKSPHILPITTTQKHTIKEKSEISNLEKPIVRGTDILKKSTSARKKRVLKGKSKSATLPKKCDNFPFDLVRSSSDSSKQEVEEQPKPGNVDKKVSDDSYSPDISTTPTKKHTLKGQSKSRTIYEKGVDLPNNLVLSKSASSIQEFEEQPQPGNVDKKVSDDSYSPDISTSPTKKHTLKGQPKSENSDEKGIKRPNNLHMSASVARKRLLKALSTIP", "length": 1642 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9D5R2-1", "protein_name": "WD repeat-containing protein 20", "gene_name": "Wdr20", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MATEGRGKETNEIKTHFTTREGLYRLLPHSEYSRPNRVPFNSQGSNPVRVSFVNLNDQTGNGNRLCFSVGRELYVYIYKGVRKAADLSKPIDKRIYKGTQPTCHDFNHLTATAESVSLLVGFSAGQVQLIDPIKKETSKLFNEERLIDKSRVTCVKWVPGSDSLFLVAHSSGNMYSYNVEHTYGTTAPHYQLLKQGESFAVHNCKSKSTRDLKWTVGEGALNEFAFSPDGKFLACVSQDGFLRVFNFDSAELHGTMKSYFGGLLCLCWSPDGKYIVTGGEDDLVTVWSFLDCRVIARGRGHKSWVSVVAFDPYTTSVEESDPMEFSDSDKNFQDLLHFGRDRANSTQSRLSKQNSTDSRPVSVTYRFGSVGQDTQLCLWDLTEDILFPHQPLSRARAHANVMNATGLPAGSNGSAVTTPGNSVPPPLPRSNSLPHSAVSNAASKGSVMDGAITSGVSKFALLSLHDRKERHHEKDRKRNHSMGHISSKSSDKLNLVNKAKTDPAKTLGTSLCPRMEDVPLLEPLICKKIAHERLTVLVFLEDCIVTACQEGFICTWARPGKVSKFQP", "length": 567 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9DAF8-1", "protein_name": "Uncharacterized protein C4orf51 homolog", "gene_name": "", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTHFLYLTPEILLPFSPLTSTEFELIRRKAQQLWQDETRWSASSMTTYSGSYREKQLDEATCNRLAQRVGQPQFEYKPTPLPGSSAYNTLPGHAGSQEAADGKGRLPDIASPSRDSPLNIKHKVAHQIWGSEVPCPTFLAYRGLRMSPCMQPKKPGFELLMSYRNRGKALLKRLQRQWDYESKLGSSEDSGTDRFSSNTSGSSGRKFK", "length": 208 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9EPV9-1", "protein_name": "Beta-defensin 5", "gene_name": "Defb5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKIHYLLFAFLLVLLSPLAGVFSKTINNPVSCCMIGGICRYLCKGNILQNGSCGVTSLNCCKRK", "length": 64 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9EPX4-1", "protein_name": "P2Y purinoceptor 12", "gene_name": "P2ry12", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEVPGANATSANTTSIPGTSTLCSRDYKITQVLFPLLYTVLFFAGLITNSLAMRIFFQIRSKSNFIIFLKNTVISDLLMILTFPFKILSDAKLGAGHLRTLVCQVTSVTFYFTMYISISFLGLITIDRYLKTTRPFKTSSPSNLLGAKILSVAIWAFMFLLSLPNMILTNRRPKDKDITKCSFLKSEFGLVWHEIVNYICQVIFWINFLIVIVCYSLITKELYRSYVRTRGSAKAPKKRVNIKVFIIIAVFFICFVPFHFARIPYTLSQTRAVFDCNAENTLFYVKESTLWLTSLNACLDPFIYFFLCKSFRNSLMSMLRCSTSGANKKKGQEGGDPSEETPM", "length": 343 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9ER80-1", "protein_name": "Receptor-transporting protein 4", "gene_name": "Rtp4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLFPDDFSTWEQTFQELMQEEKPGAKWSLHLDKNIVPDGAALGWRQHQQTVLGRFQCSRCCRSWTSAQVMILCHMYPDTLKSQGQARMRIFGQKCQKCFGCQFETPKFSTEIIKRILNNLVNYILQRYYGHRKIALTSNASLGEKVTLDGPHDTRNCEACSLNSHGRCALAHKVKPPRSPSPLPKSSSPSKSCPPPPQTRNTDFGNKTFQDFGNRTFQGCREPPQREIEPPLFLFLSIAAFALFSLFTR", "length": 249 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9FFP9-1", "protein_name": "Serine/threonine-protein kinase SRK2H", "gene_name": "SRK2H", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDKYEVVKDLGAGNFGVARLLRHKETKELVAMKYIERGRKIDENVAREIINHRSLRHPNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEAEARYFFQQLICGVDYCHSLQICHRDLKLENTLLDGSPAPLLKICDFGYSKSSLLHSRPKSTVGTPAYIAPEVLSRREYDGKHADVWSCGVTLYVMLVGGYPFEDPDDPRNFRKTIQRIMAVQYKIPDYVHISQECRHLLSRIFVTNSAKRITLKEIKKHPWYLKNLPKELTEPAQAAYYKRETPSFSLQSVEDIMKIVGEARNPAPSSNAVKGFDDDEEDVEDEVEEEEEEEEEEEEEEEEEEDEYEKHVKEAHSCQEPPKA", "length": 360 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9FLZ3-1", "protein_name": "SNF1-related protein kinase catalytic subunit alpha KIN12", "gene_name": "KIN12", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDGSSEKTTNKLVSILPNYRIGKTLGHGSFAKVKLALHVATGHKVAIKILNRSKIKNMGIEIKVQREIKILRFLMHPHIIRQYEVIETPNDIYVVMEYVKSGELFDYIVEKGKLQEDEARHLFQQIISGVEYCHRNMIVHRDLKPENVLLDSQCNIKIVDFGLSNVMHDGHFLKTSCGSPNYAAPEVISGKPYGPDVDIWSCGVILYALLCGTLPFDDENIPNVFEKIKRGMYTLPNHLSHFARDLIPRMLMVDPTMRISITEIRQHPWFNNHLPLYLSIPPLDTIDQAKKIEEEIIQNVVNIGFDRNHVVDSLANRIQNEATVAYHLILDNRNQNSVPNDPFQSKFKEISDGIFNSTLPVQNITSHVGHSFSALYGLKSNVKDDKTWTLGLQSQGSPYDIMTEIFKALQNLKICWKKIGLYNIKCRWVRSFAYYKNHTIEDECAIILPTVIKFEIQLYKVREGKYLLDILRIDGPQFIFFDLCVAFLRELGVL", "length": 494 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9FVV4-1", "protein_name": "DEAD-box ATP-dependent RNA helicase 55", "gene_name": "RH55", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDSSPPNTIIEEAPPRFSELKPPLSEDIIEALDRSGFEVCTPVQAETIPFLCSHKDVVVDAATGSGKTLAFLLPFIEIIRRSNSYPPKPHQVMGVIISPTRELSAQIHKVARAVRLDFAKCREVEADMNTLEEEGANLLIGTPGRLSDMMKRMEFLDFRNLEILILDEADRLLDMGFQKQVNYIISRLPKQRRTGLFSATQTQAVADLAKAGLRNPYLKCEADQKSSQLVHLLIENKNKKLVVFFMTCACVDYWGLVISKIPSLKSISFFPTHGKMDQKGRDTALASFTEASSGVLLCTDVAARGLDIPGIVYIRSLAIKDREVLEKGLKAFVSFVRAYKEHQCSYIFSWKGLEIGKLAMGYGILSFPYISEVKQDRIGIVGFTPVQGITFEDIKFKNKSREKQRQQNLLARKDKLQQEKRGKRKKSSKEAVDDSNKASRKRKLTGRQRQTIQTAQDEEEMNLRL", "length": 465 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9JI02-1", "protein_name": "Secretoglobin family 2B member 20", "gene_name": "Scgb2b20", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLGLLVTGELSFQTTEACLPFFEGYASVLSGSRVWLYQELQAFNATAEEKVALEKIQDCFSEERIRNILLEPKIMEAMVASPECLSYYGLDNIRSILDYISKLLGE", "length": 112 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9JJQ7-1", "protein_name": "X-linked lymphocyte-regulated 4B", "gene_name": "Xlr4b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASKIKGRPPKQPKVTPALPSNDSQQLHENNPGNNLALETCGESSSSHGTGGPKPGPSKKTLNERKRKYGVSVNKTVQNIEWNVDHFLKVQHERRQELYKDYSHQFLTLVMMWNIDVDQIKKQAGKLSDILDEQQKLFQQFQSIHMQKIEEFKELCDRHLKNLQAIKCCRRKAIIEEARKLMDYLEKRVTEETVHVNKQEAKDGVQSSLLSLLIS", "length": 215 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9JLV9-1", "protein_name": "Prolactin-2C5", "gene_name": "Prl2c5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLPSLIQPCSWILLLLLVNSSLLWKNVASLPMCAMRNDRCFMFFEDTFELAGSLSHNISIEVSELFTEFEKHYSNVPGLRDKSPMRCHTSFLPTPENKEQARHIRYEALLKSGDMILDAWENPLDYLVSELSTIKNVPDIIISKATDIKKKINAVQNGVNALMSTMNGDEENKNPAWFLQSDNEDARIRSSYGMISCLDNDFKKVDIYLNILKCYMLKIDNC", "length": 222 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9LJY9-1", "protein_name": "Cytochrome P450, family 705, subfamily A, polypeptide 18", "gene_name": "CYP705A18", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MATLISVDFQHCFMYIILLCLFSLLCYSLFFRKPKGTRVGCDLPPSPPSLPIIGHLHHLLSSLTHKSLQKLSSKYGPFLHLRIFSVPIILVSSASVAYEIFKAHDVNVSSRGAAAIDESLLFGSSSFIYAPYGDYWKFMKKIFATKLLRPQVLENSRGVRAEELKRFYRRILDKARKNENIEISKESAMLMNNILCRMSMGRSFSEENGEAERVRGLVGESYALVKKIFFAATLRRLLEKLRIPLFRKEIMGVSDRFDELLERIIVEHKDKLEKEHQVMDMMDVLLAAYRDKNAEYKITRNHIKSFFVDLFVGGTDTSVQTTQWTMAEIINNPNILQTLRKEIDSVVGKSRLIHETDIPNLPYLQAVVKEGLRLHPPGPLLIRTFQERCEMKGFYIPEKTTLVINAYAVMRDPDSWEDPDEFKPERFLSYSRSGQEDEKEQTLKYLSFGGGRRGCPGVNLGYIFVGTAIGMMVQCFDWKIEGDKVNMEETYGGMNLTMVNPLKCTPVPRTQPFSFTSNLEILSS", "length": 524 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9LSY1-1", "protein_name": "SKP1-like protein 8", "gene_name": "ASK8", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSTKKIMLKSSEGKTFEIEEETARQCQTIAHMIEAECTDNVILVLKMTSEILEMVIEYCNKHHVDAANPCSDDDLEKWDKEFMEKDKSTIFALTNAANFLNNKSLLHLAGQTVADMIKGNTPKQMREFFNIENDLTPEEEAAIRRENKWAFE", "length": 152 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9LTG5-1", "protein_name": "Callose synthase 4", "gene_name": "CALS4", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MNQPNRGQILQTVFSHFFPVASPDSELVPSSLHEDITPILRVAKDVEDTNPRSLFLQDLDIKSVDDSINILSGHSHALDKANELDPTSSGRDVRQFKNTILQWLEKNNESTLKARQKSSDAHEMQSFYQQYGDEGINDLLNAGAGSSSSQRTKIYQTAVVLYDVLDAVHRKANIKVAAKILESHAEVEAKNKIYVPYNILPLDPDSKNHAMMRDPKIVAVLKAIRYTSDLTWQIGHKINDDEDVLDWLKTMFRFQKDNVSNQREHLILLLANVQMRQTQRQPNLLDDRALDTVMEKLLGNYNKWCNHVGLESSLRFPKDKQQKVVQQRKLLYTGLYLLIWGEAANLRFMPECLCYIYHHMAFELFEMLESKGSKKKYKPKNPTYSGKDEDFLTKVVTPVYKTIAEEAKKSGEGKHSEWRNYDDLNEYFWSKQYLDKLGWPMKANADFFCKTSQQLGLNKSEKKPDLGDGCVGKVNFVEIRTFWHLFRSFDRMWSFYILSLQAMIIIAWNETSESGGAVFHKVLSVFITAAKLNLFQAFLDIALSWKARHSMSTHVRQRYIFKAVAAAVWVLLMPLTYAYSHTSIFIVAILIYLSPNMLPEMLLLIPSIRRTLEKSDFRPVKLIMWWSQPELYIGRGMHESAWSIYKYMMFWIVLLTSKLAFSYYVEQIKPLMGPTKEIMSVPMPGYWLPEFFPHVKNNRGVVITLWSPVILVYFMDTQIWYAIVSTLVGGLYGAFRHIGEIQTLGMLRSRFQSLPGAFNACLIPNENTKEKGIKLAFSRKCHKIPNTNGKEAKQFSQMWNTIINSFREEDLISNRELELLLMSCWAYPDLDFIRWPIFLLASKIPIAVDIAKKRNGKHRELKNILAEDNCMSCAVRECYASIKKLLNTLVTGNSDLMLITTVFTIIDTHIEKDTLLTELNLSVLPDLHGHFVKLTEYVLQNKDKDKIQIVNVLLKILEMVTKDILKEEIKRLHLLLTVKESAMDVPSNLEARRRLTFFSNSLFMEMPGAPKIQNMLSFSALTPYYSEDVLFSTFDLEKENDGVSILFYLQKIFPDEWKNFLERVKCGTEEELDAIDYLKEEIRLWASYRGQTLTKTVRGMMYYQKALELQAFFDLANERELMKGYKSAEASSSGSSLWAECQALADIKFTYVVACQQYSIHKRSGDQRAKDILTLMTTYPSLRVAYIDEVEQTHIYSKGTSENFYYSALVKAAPQTYSTDSSDSGHMLDQVIYQIKLPGPPIIGEGKPENQNNAIIFTRGEALQTIDMNQDYYIEEAFKMRNLLQEFLEKNGGVRYPTILGLREHIFTRSVSCLAWFMSNQEHSFVTIGQRVLANPLKVRFHYGHPDVFDRVFHLTRGGVSKASKVINLSEDIFAGFNSTLREGTVSHHEYIQVGKGRDVGLNQISMFEAKIANGSGEQTLSRDLYRLGHQFDFFRMLSCYFTTVGFYFCSMLTVLTVYVFLYGRLYLVLSGVEKELGNKPMMMEIILASQSFVQIVFLMAMPMIMEIGLERGFYDALFDFVLMQLQLASVFFTFQLGTKFHYYCKTLLHGGAEYRGTGRGFVVFHAKFAENYRFYSRSHFVKATELGILLLVYHIFGPTYIGLFTISIWFMVGTWLFAPFLFNPSGFEWHEIVEDWADWKKWIEYDNGGIGVPPEKSWESWWEKDIEHLQHSGKWGIVVEIFFALRFFIFQYGLVYQLSAFKNKYSSLWVFGASWLLILILLLTVTVLDYARRRLGTEFQLLFRIIKVSLFLAFMAIFITLMTCRLILPQDVFLCMLALIPTGWGLLLIAQSCKPLIQQPGIWSWVMTLAWVYDLVMGSLLFIPIAFMAWFPFISEFQTRMLFNQAFSRGLHISRILSGQRKHRSSKNKD", "length": 1871 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9LU95-1", "protein_name": "Pyruvate kinase", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEMLLGGQATNGALRSKTKIVCTLGPASRSVEMIEKLLKAGMNVARFNFSHGSHSYHQETLDNLRTAMDNTGILCAVMLDTKSPVIRTGFLKEGKPIQLKQGQEITISIDYKIQGDSNTISMSYKKLAEDLKPGDVILCSDGTISLNVLSCDKYLGLVRCRCENSALLGERKNVNLPGIVVDLPTLTEKDKEDIMQWGVPNKIDIIALSFVRKGSDLIQVRKLLGEHSKSIMLMSKVENQEGVMNFDKILENSDAFMVARGDLGMEIPIEKMFLAQKTMINKANAHGKPVVTATQMLESMTVSPRPTRAEATDVANAVLDGTDCVMLSGETAAGAHPETAVLTMSRICKEAEDFIDYDILHKKTLGMVSLPLSPIESLAASAVSTARSVFASAIVVLTRGGYTAELVAKYRPSVPILSVIMPEIAECSDSVAHVARRGLIYRGIIPVVGCSARDSTEEMIRLAIGFAKTKGICKTGDSIVALHKIDGSSIVRIVSVE", "length": 497 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9LX08-1", "protein_name": "Annexin D6", "gene_name": "ANN6", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MASLKIPANIPLPEEDSEQLHKAFKGWGTNEGMIISILAHRNATQRSFIRAVYAANYNKDLLKELDGELSGDFERVVMLWTLDPTERDAYLANESTKLFTKNIWVLVEIACTRPSLEFFKTKQAYHVRYKTSLEEDVAYHTSGNIRKLLVPLVSTFRYDGNADEVNVKLARSEAKTLHKKITEKAYTDEDLIRILTTRSKAQINATLNHFKDKFGSSINKFLKEDSNDDYVQLLKTAIKCLTYPEKYFEKVLRRAINRMGTDEWALTRVVTTRAEVDLERIKEEYLRRNSVPLDRAIANDTSGDYKDMLLALLGHDHA", "length": 318 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9LXS7-1", "protein_name": "Citrate synthase 1, peroxisomal", "gene_name": "CSY1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEISERARARLAVLNAHLTVSEPNQVLPAIEPWCTSAHITAAPHGSLKGNLKIVDERTGNEYQVPVSEHGTVKTVDLKKITTGKDDKGLNLYDPGYLNTAPVRSSISYIDGDEGILRYRGYPVEELAEKSTYTEVTYLLIYGNLPSQRQLADWEFAISQNSAVPQGVLDMIQSMPNDVHPVGALVTAMSALSIFYPDANPSLMGLGVYKSKQVRDKQIVRVLGQAPTIAAAAYLRKAGKPPVQPLSNLSYSENFLYMVESMGDRSYKPNPRLARVLDILFILQAEHEMNCSTAAARHLSSSGGDVYTAVSGGVGAIYGPLHGGAVEATINMLSEIGTVENIPEFIESVKNKKRRLSGFGHRIYKNYDPRGKVVKKLADEVFSILGRDPLVEVGDALEKAALSDEYFVKRKLYPNVDFYSGLINRAMGIPSSFTAVSRIAGYLSHWRESLDDPDTKIMRPQQVYTGAGIRHYETVRERTKL", "length": 480 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9LY06-1", "protein_name": "Glycine/proline-rich protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MITCILKISISSFIVLRIFSFLWFSRWFCCGLCGRFWFRCWFCCWFQFWFRCRFYCRFDTGFDVRFAAGFAADLTIGFTIGFDSGFATFLDVGLDDGFATGLDISFAGGFVTGFATDFDVGFDTGFTIGFDTGFDVGLPAVFSIGFDTGFAVGFAISFTVGFDAGFPTGFFVSLDVGFVADFVIGFATGIGVGFEVDFATDFDTCFATGFAVSFDVGFAGGFSIGFAADFANGFTVGFDGGFDASFFVGLDVGFVVGFVTSFAAGLDVGFAIDFATGFDTGFAFGLAFGFDVGFAAGFAVGFATGFTVVFDVGFASDFFVGLDVGFLTGFATDFDIGFVVDFDIGFATGFVVGFDDGSIVGLVVGLPASLDDGLAIDFVVGLDIGFVTGLFVGLVDGLTTDLDVGLVDGLDDGLDDGLDVDLVVVGFVVDGLAVDLDVGLGVGLTVGFVDGLDVGFDDGLDADTVDGLDVGLDDGLDVDLVDGLDIGLDDGLDVGLDDGLDFGLVDGLDVDLDDGLDVDLVDGLDIGLDDGLDVGLDDGLDFGLVDDGLVVGLFDVFVGTGLSWEIPPPGKLPPDASPLGIGSFGVGPPGASPFIASPSGEGPLSEGLLGIRSFGISPLSIRPLGISPLGISPPNIEPSKADASDADPSNAGPLGISPLSIDPPVAGASDEGPLGKLPPDLSPPGKGSSGEGPLVESPPSEGPLGVDPLGAGSLGISPLGKSPLRIRPLGISPFGKIPSNIDPSSALASDGGPPDEPASAEGSPDVGIFGISPPIIDPPVEGASDGDPPEKLSLDISPLGKGPSGVSLLGAGPPGVGPVIASPPGEGPRDAGPLGAGSLGISPLNIRRLGISPSGISPPNIDLPVAGTSIGGPPDEGASDGGPPDVGPFGISPPIIDPPGESESDGDPAGKLPLDISPLSKGPSCVSPLGVGPVIASPPGEGPLDAGPLGAGSLGISPLNIRRLSISPFGISPSSIDSPVAGTSIGGPPDEGASDGGPPDVGPFGISPPIIDPPGEDASDGDPPGKFPLDISPLGKCPSGVSPLGVGPPGVGPVIASPPGEGPLDAGPLGAGSLGISPLNIRRLGISPFGISPPNIDLPVAGTSIGGPLDEGASDGGPPDVGPFGISPSIIDPPGEGAFDGDPPGKLPLDISPVGKGPSGVSPPGAGPPGDGPVIASPPGESPLDAGPLGAGSLGISPFGISPPNIDWPVAGTSFGGPPGEGASNGGPLVVGPFDMPVVGASDGDALEKLPLDISLPGKGPSDVGPPGAGLPGAAPPGVDLSNVGASDRGASGEGASDGCPPDVGPFDICLLSIDPPVVGASDGGPPDEGASNGGPPDTDSFGGDPLCASPLGIDPPIVDASDGDPFGAGSPDEDPSNENASGEGASGESPPCSDVSCKGPSSAGASIGCSLDNGASTPSSPDTFLSNVFPSDKSSPDAFSPDVAALVTLPSGKDPFDISPPIVALLDVSPLGKTSSDAYSSGISPGIFEKSFPLVKLQTIEYM", "length": 1504 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9M2S0-1", "protein_name": "Probable mannose-1-phosphate guanylyltransferase 2", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MKALILVGGFGTRLRPLTLSLPKPLVDFANKPMILHQIEALKAIGVDEVVLAINYEPEQLLVMSKFSNDVEATLGIKITCSQETEPLGTAGPLALARDKLVDGSGQPFFVLNSDVISDYPLEEMIAFHNAHGGEASIMVTKVDEPSKYGVVVMEEATGRVERFVEKPKLFVGNKINAGIYLLNPSVLDRIELRPTSIEKEIFPQIAEAEKLYAMLLPGFWMDIGQPRDYITGLRLYLDSLRKKSPSKLATGPHILGNVLVDETAEIGEGCLIGPNVAIGPGCVVESGVRLSHCTVMRGVHVKRYACISSSIIGWHSTVGQWARVENMSILGKNVYVCDEIYCNGGVVLHNKEIKSDILKPDIVM", "length": 364 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9NR96-1", "protein_name": "Toll-like receptor 9", "gene_name": "TLR9", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGFCRSALHPLSLLVQAIMLAMTLALGTLPAFLPCELQPHGLVNCNWLFLKSVPHFSMAAPRGNVTSLSLSSNRIHHLHDSDFAHLPSLRHLNLKWNCPPVGLSPMHFPCHMTIEPSTFLAVPTLEELNLSYNNIMTVPALPKSLISLSLSHTNILMLDSASLAGLHALRFLFMDGNCYYKNPCRQALEVAPGALLGLGNLTHLSLKYNNLTVVPRNLPSSLEYLLLSYNRIVKLAPEDLANLTALRVLDVGGNCRRCDHAPNPCMECPRHFPQLHPDTFSHLSRLEGLVLKDSSLSWLNASWFRGLGNLRVLDLSENFLYKCITKTKAFQGLTQLRKLNLSFNYQKRVSFAHLSLAPSFGSLVALKELDMHGIFFRSLDETTLRPLARLPMLQTLRLQMNFINQAQLGIFRAFPGLRYVDLSDNRISGASELTATMGEADGGEKVWLQPGDLAPAPVDTPSSEDFRPNCSTLNFTLDLSRNNLVTVQPEMFAQLSHLQCLRLSHNCISQAVNGSQFLPLTGLQVLDLSHNKLDLYHEHSFTELPRLEALDLSYNSQPFGMQGVGHNFSFVAHLRTLRHLSLAHNNIHSQVSQQLCSTSLRALDFSGNALGHMWAEGDLYLHFFQGLSGLIWLDLSQNRLHTLLPQTLRNLPKSLQVLRLRDNYLAFFKWWSLHFLPKLEVLDLAGNQLKALTNGSLPAGTRLRRLDVSCNSISFVAPGFFSKAKELRELNLSANALKTVDHSWFGPLASALQILDVSANPLHCACGAAFMDFLLEVQAAVPGLPSRVKCGSPGQLQGLSIFAQDLRLCLDEALSWDCFALSLLAVALGLGVPMLHHLCGWDLWYCFHLCLAWLPWRGRQSGRDEDALPYDAFVVFDKTQSAVADWVYNELRGQLEECRGRWALRLCLEERDWLPGKTLFENLWASVYGSRKTLFVLAHTDRVSGLLRASFLLAQQRLLEDRKDVVVLVILSPDGRRSRYVRLRQRLCRQSVLLWPHQPSGQRSFWAQLGMALTRDNHHFYNRNFCQGPTAE", "length": 1032 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9QUG3-1", "protein_name": "Prion-like protein doppel", "gene_name": "Prnd", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKNRLGTWWVAILCMLLASHLSTVKARGIKHRFKWNRKVLPSSGGQITEARVAENRPGAFIKQGRKLDIDFGAEGNRYYAANYWQFPDGIYYEGCSEANVTKEMLVTSCVNATQAANQAEFSREKQDSKLHQRVLWRLIKEICSAKHCDFWLERGAALRVAVDQPAMVCLLGFVWFIVK", "length": 179 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9SAC9-1", "protein_name": "AP-1 complex subunit mu-1", "gene_name": "AP1M1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAGAASALFLLDIKGRVLVWRDYRGDVTAAQAERFFTKLIETEGDSQSNDPVAYDNGVTYMFVQHSNIYLMIASRQNCNAASLLFFLHRVVDVFKHYFEELEEESLRDNFVVVYELLDEMMDFGYPQFTEARILSEFIKTDAYRMEVTQRPPMAVTNSVSWRSEGLKFKKNEVFLDVIESVNILVNSNGQIVRSDVVGALKMRTYLSGMPECKLGLNDRILLEAQGRAIKGKAIDLEDIKFHQCVRLARFENDRTISFIPPDGSFDLMTYRLSTQVKPLIWVEAHIERHSRSRVEMLVKARSQFKDRSYATSVEIELPVPTDAYNPDVRTSLGSAAYAPEKDALVWKIQYFYGNKEHTLKADFHLPSIAAEEATPERKAPIRVKFEIPKFIVSGIQVRYLKIIEKSGYQAHPWVRYITMAGEYELRLM", "length": 428 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SCN2-1", "protein_name": "Cytochrome P450 71B31", "gene_name": "CYP71B31", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSMFLGLLFLFPLFFILFKNLLPPRKKLPPGPTGLPLIGNLHQLGRLLHSSLHKLSLEHGPVMLVRWGVVPMAVFSSNEAAKEVLKTHDLETCNRPKLVANGLFTHGYKDIGFTQYGEEWREMKKFVGLELFSPKKHKSFRYIREEEGDLLVKKISNYAQTQTLVDLRKSLFSYTASIIFREAFGQNFRECDYINMDKLEELVQETETNVCSLAFTDFFPRGLGWLVDRISGQHSRMNIAFSKLTTFFEDVIDELLKTKQLDDHSDLVTAMLDVINRPRKFGSLKITYDHLIAMMSDVVLAGVNAGTVTMIWTMTELTRHPRVMKKLQEEIRATLGPNKERITEEDLEKVEYLNLVIKESFRLHPPAPLLLPRETMSDIEIQGYHIPKNAHVKINTYAIGRDPKRWTNPEEFNPERFLNTSINYKGQHYELLPFGAGRRNCPGMTLGITILELGLLNILYYFDWSLPSGMTIKDIDMEEDGALNIAKKVPLQLVPTLP", "length": 498 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SJ39-1", "protein_name": "Cytochrome P450, family 705, subfamily A, polypeptide 6", "gene_name": "CYP705A6", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAAILSVDFQNCFIFIVLCLFSLFCYSLFFKKPKHPRGCDLPPSPPSLPIIGHLHLLFSPLTHKSLQKLSSKYGHLLHLRIFNVPVILVSSASVAYEIFRAHDVNVSSRGVAAIDESLLFGSSGIITAPYGDYWKFMKKLIATKLLRPQSLESSRGIRGEELTRFYNSLLDKARMTESVEISTEAMKLVNNTLCRMSMGRSFSEENGEAEKIRGLVGESYALTKKMFLASLLRKPLKKLRISLFEKEIMGVSDRLDELLERILVEHEEKLHEEHQGTDMMDVLLAASGDENAEYNITRNHIKSFFVEIFIGATDTSVQTTQWTMAEILNHPNVLERLRKDIDSVVGKTRLIHETDLPNLPYLQAVVKEGLRLHPPGPLLVRTFQERCKIKGFYIPEKTTLVINAYAVMRDPDSWEDPDEFKPERFLRAPPMGGSLDKFIEFS", "length": 442 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SMT4-1", "protein_name": "Large ribosomal subunit protein eL13y", "gene_name": "RPL13C", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MKHNNVIPNGHFKKKWENYVKTSFNQPAMKTRRRIARQNKAVKIFPRPTAGPIRPVVHAQTLTYNMKVRAGKGFTLEELKAAGIPKKLAPTIGISVDHHRKNRSLEGFQTNVQRLKTYKAKLVIFPRCARTVKVGDSAQQELANATQVQVDHMPIVREMPTMELVKLTSDMKLFNAYDKIRLEGINKRHAGVRAKRAAEAEKEEKK", "length": 206 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SSB4-1", "protein_name": "26S proteasome regulatory subunit 7 homolog B", "gene_name": "RPT1B", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MIIRDIMEDPENEGPHNMRSDFEPLLSVLRLRDYETGDIIEFDSTEASEEALSDITEFGSTEASEAHFEEPYSARIKKVEKEINELAEKICNLGIKESDTGLAPPNQWDLVSDKQMMQEEQPLLVATCTQIISPNTEDAKYVVDIKKIGKYVVGLGDKASPTDIEAGMRVGVDQKKYQIQIPLPPKIDPSVTMMTVEEKPDATYSDIGGCKEQIEKIREVVELPMLHPEKFVRLGIDPPKGVLCYGPPGSGKTLVARAVANRTGACFIRVVGSELVQKYIGEGARMVRELFQMARSKKACILFFDEIDAIGGARFDDGVGSDNEVQRTMLEILYQLDGFDARGNIKVLMATNRPDILDPALLRPGRLDRKVEFCLPDLEGRTQIFKIHTRTMSCERDIRFELLAGLCPNSTGADIRSVCIEAGMYAIGARRKSVTEKDFLDAVNKVVKGYQKFSATPKYMAYYI", "length": 464 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SVM4-1", "protein_name": "Serine hydroxymethyltransferase 5", "gene_name": "SHM5", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEPVYSWGNTHLDFVDPEIYDLIEKEKHRQCRGIELIAAENFTSVAVMEALGSCLTNKYSEGMPGNRYYGGTEFIDEIESLCRSRSLEAFHCNPEKWGVNVQPYSGSPANFAAYTALLQPHDRIMGLDLPSGGHITHGYYSSGGKNISATSIYFENLPYKVDSKTGYIDYDKLEEKAMDFRPKLIICGGTSYPREWDYARFRAVADKVGAFLLCDMAHNSALVAAQEAADPFEYCDVVTTSTHKSLRGPRAGMIFYRKGPKPAKKGQPEGEVYDFDAKINSAVFPALQSGPHNNKIGALAVALKQVMAPSFKVYAKQVKANAACLASYLINKGYTLVTDGTDNHLILWDLRPLGLTGNKVEKVCELCYITLNRNAVFGDTSFLAPGGVRIGTPAMTSRGLVEKDFEKIGEFLHRAVTITLDIQEQYGKVMKDFNKGLVNNKEIDEIKADVEEFTYDFDMPGFFISESRND", "length": 470 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SWH4-1", "protein_name": "Syntaxin-42", "gene_name": "SYP42", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MATRNRTTVYRKHRDACKSARAPLSLSASDSFGGPVIEMVSGSFSRSNHSSYAPLNSYDPGPSSSDAFTIGMPPAWVDDSEEITFNIQKVRDKMNELAKAHSKALMPTFGDNKGIHREVEMLTHEITDLLRKSEKRLQMLSTRGPSEESNLRKNVQRSLATDLQNLSMELRRKQSTYLKRLQQQKEGQDEVDLEFNVNGKMSRLDEEDELGGMGFDEHQTIKLKEGQHVSAEREREIQQVLGSVNDLAQIMKDLSALVIDQGTIVDRIDYNVQNVSTSVEEGYKQLQKAERTQREGAMVKCATILLVLCLIMIVLLILKNILF", "length": 323 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SYN6-1", "protein_name": "SOUL heme-binding family protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEAALSIFKLSFLLTLLSGGSDLIDSLPPNCNRAECPSYEVVHAGNGYEIHRYNTTVWISTEPIQDISLNEASGNGWNQLSDYMNGNNDYHQRIEIALPYITQVSQNLSTFIVSFFVPKAFQPDPPPGNNLHVQRWDSRYVAVKQISGYVADHKIGKQVAELKASLQGTVWAKAIEKSRETGGVGSAWAYTVAQFSWPFQWSQRVNEIWFPFEMEDEETVSIVTQ", "length": 225 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SZB4-1", "protein_name": "Putative DEAD-box ATP-dependent RNA helicase 43", "gene_name": "RH43", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEVDDGYVEYVPVEERLAQMKRKVVEEPGKGMMEHLSDKKKLMSVGELARGITYTEPLSTWWKPPLHVRKMSTKQMDLIRKQWHITVNGEDIPPPIKNFMDMKFPSPLLRMLKDKGIMHPTPIQVQGLPVVLSGRDMIGIAFTGSGKTLVFVLPMIILALQEEIMMPIAAGEGPIALVICPSRELAKQTYDVVEQFVASLVEDGYPRLRSLLCIGGVDMRSQLDVVKKGVHIVVATPGRLKDILAKKKMSLDACRLLTLDEADRLVDLGFEDDIRHVFDHFKSQRQTLLFSATMPAKIQIFATSALVKPVTVNVGRAGAANLDVIQEVEYVKQEAKIVYLLECLQKTTPPVLIFCENKADVDDIHEYLLLKGVEAVAIHGGKDQEDRDYAISLFKAGKKDVLVATDVASKGLDFPDIQHVINYDMPGEIENYVHRIGRTGRCGKTGIATTFINKNQSEITLLDLKHLLQEAKQRIPPVLAELNGPMEETETIANASGVKGCAYCGGLGHRILQCPKFEHQKSVAISSSRKDHFGSDGYRGEV", "length": 542 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9T0E0-1", "protein_name": "Putative ATPase, plasma membrane-like", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MATGDSLEDIKIEIDDDLEKIPIEEVFKKLRCSREGLSGAEGKERLKIFGPNKLENKKKEHITLRFFALMFKPLSWVIQAAAIMAMLFANGDGRQLFLGIVCLLIVNTIICYLKEDDAANVVAMARAGLSPKTKVLRDGKWSEQEASILVPGDIVSIKPGDIIPCDARLLEGDTLKVDQSALTGEFGPITKGPGEEVFSGTTCKQGEMEAVVIATGVHTFSGTTAHLVDNRTNKVGHFRKVVTEIENLCVISIAIGISIEVIVMYWIQRRNFSDVINNLLVLVIGGIPLAMPTVLYVIMVTGSLRLYRTGTITQRITAIEDMAAIDVLCSDKTGTLTLNKLSVDKNLIKVYSKDVEKEQVLLLAARASRIENRDGIDAAMVGSLADPKEARAGIREVHFNLVDKRTALTYIDGNGDWHRVSKGTPEQILDLCNARDDLRKSVHSAIRNYAERGLKSFAISWFRNTNCNTVFFFPYQLCSEHKYHIVNKLQERHICGLIGDGVDDVPSLKKADVGIAVANATEAARAASDIVLTEPGLSVIIDAVLASRAILQQMKHYTIYAVSITIRVVFGFMFIALIWKFDFSPFMVLAIALLNEETTKAITMDNVTNPSPTPDSLKLKEIFATGVVYGSYMALITVVFFWAAYRTDIFPRTFHVRDLRGNEAEMMCALYLQVSIMSQALFFVIQSRSWFFVERPGELLFLSFVTVQTIATTLAVYASWETARIEGIGWSWAGVIWLYNIIFFFPLDIMKFGIRYILTGKAQSLFDNMVHLVLNSYAKLSNGIYNHTQADHTYSLLEVSTPPSQDLRGVGWV", "length": 813 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9T0H7-1", "protein_name": "Histone H2A.8", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MVCNTNILKDVSTKISAFENVRMIMVEGEMFQVARIHKQLKNRVSAHSSVGATDVVYMTSILEYLTTEVLQLAENTSKDLKVKRITPRHLQLAIRGDEELDTLIKGTIIGGSVIPHIH", "length": 118 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9VXF6-1", "protein_name": "Calnexin 14D", "gene_name": "Cnx14D", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MAWKMLFAILLLLSAAKTGYLAPESENSVEDVQIEPGAIYGDEKFAYKSPVIDAEKFYFADHFDDVEASRKRWVLSQAKKNDIADEIAKYDGIWNWESPQRIFWANDLGLVLKSKAKHAAIAAPFRQPFDFKSNKPLVVQYELTLQEGQDCGGSYLKLLSAGKGTEQLNRFNDKTPYTIMFGPDKCGNNLKMHFIFRHVNPLNGNITEKHCKKPNARLGVPFTDKLPHLYQLVVRPDNSFEIRLDHKIIKEGSLLTDFVPPVNPPAEIDDPNDHKPESWDERKKIPDPNAHKPEDWDEDAPPHLPDTDAVMPNGWLEDEPDMIFDPTAIEPEDWNSEIDGEWEAPLVENPVCKKAPGCGKWKAPLIPNPNYKGKWSAPMIENPNNQGKWAPRKIANPDFFEDLKPFQMTPINAVGLELWSMSSDILFDNLIITDDVELARDFAANSFDIKRLYIDRESFGNKVVELARANRAIWGIVIVAIAVPVAITIFCKFGLGPSRVAAAKKAAAAAAKKTDDPQPDDDLGAEEEEKLEKGKKEEEKKEEEEEEEKEENKEEKKEEEKDDEKEMKDCEEEEDDEEKDDEEKTDERAAGDTNKESTPLSASPKKNQKSYLDNNEDEEDTLKNKEPTPKKRKRKALKE", "length": 639 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9W240-1", "protein_name": "K Homology domain-containing protein", "gene_name": "cg3927", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "METPSELTEKQNQDQPTYQPRLNEVAQKFLADLDAERKRLSAEFPLCALLIDESVDRVYSTGRIPGKEPFADVYQQKPMKIIQKVFVPVNKFPKFNFTGKILGPKGNSLRRLQEETHCKIVIKGRNSMRDRNKEEELRSSGDPRYAHLHKDLFLEVSAVAPPAECYARIAYALAEIRKYLIPDDNDDVWHEQQRELMEMNPKSAKKSNGLNMAPYRSNFDKAIGAIRNRAPKYNNQIRRVTENPREVAYMEEVEYDYDEHLMFCSPVVRL", "length": 270 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9W4G6-1", "protein_name": "Uncharacterized protein", "gene_name": "Dmel\\CG2861", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDYEIIEFVRRHISHIDISAETRMRYPDPISNNNFDWNSIGLGEQEDAIGQDQQSQALNENANNVSPDVPPSTIAEPTLEPSTIEGNQGQNPRIISSMPDMMPMANSFNPLININQEAGVVINTGINSIDNGLPSTYSEHISQPTNTESTRNMNSSIFDIPSDLDNNSSNESGDEVTQPTAKQSKINANFVCKIESDTNMDKLPTTSNNTNDKPPNNTDSDSDIISISDLIEDLNLDFNQLPITSCDVETHPADTQSNIDANLPYDLISAINMDFVNPANRTYMSAANSTRGTAYKIRKPRTVKRIIKAPSKSNIGKLLREAAKKENAAAGTQRPKKATSTITSSVQNFPNPNNWPACPFPMQNGTMPADEPNDLMPTVSQSLTVPAAQNRPIQTIGKIIKPPVKRTYTKRANKTNNTNIPNKNSTGVIQSNGVAPTIRQGLVEPGGTNILMPWNRQIPMVSVAENPRVQTIDKIIVPPPKRTYKKRVNKTVNTNQSSESAVGDGAPSAPIQSIPKVRKPRGPGKKTAKMVPGQESQQDIPLGVPPNGEAPQTSSQAPVPRVKRAYRKRANNTNNTNILNVNSTGVMESNGGGPTIPNSQQIPNVAVVLNLPIQPIKPKAPRKPRAKKVCNQQPGTDIPFGVSAQGQTAQIKPKPKPRAPRVPKEPKAPKEPKAPKVPKAPRVPKAPRVPKAPRVPKAPRVPKPPKEPKPPKEPKPPKQPKAPRVPKEPKPPKVPKEPKAPRAPRAPRVPKAPKEPKVPKIPKNPRVPKAPRQPKASMNKIQNTVKVPLPIEPVPLETPTYINPINTPVQSTVGEILALGSMPPISPIKFPVLFDEHAAQHTVANSNMPQSSLPTLDIPQLPTRNNKQPSTKSAEDTEILGLGKNKNAMKSDGRIKQGRVSKPSLRFSPSSSSLRPVVRSLSSSSSSSSSWSSCTTCSTCSSCSTCSSSSDSSQSSRSRNRKRRSPKVPIPHKLFESNGEINFQLGQPTRLESPSPPPPVPMQACGTFEEHLTDLTLVRVHAISPLRSPTYDFDFDLPEPMLSEESSSSSSESNDESNVNCQMAPNSQNVSMHFLKVMVFYNCYVLFQQLEKKHQSLFEESSSSSSSESNDETNVNCQMTPNSQNQKKLQSAPIREPSPDQPPEAASRSSNGGTIGPCNLKAFRRDFMISNAENTGFTNPSELNLKKCATKVCTPMERNSGSQLPIQNRFILPNSNKEEGKMNVEPVMPKHKPSRIPIRTKTPIALNLMKEPEDNARKPKNILKPFFSNADVNPCSSTDYEPNFKPCESPLPAKQNDFKLINKDKKSWVSHYQEQESQELKENSFFYAKFNLPNIPKKSFKDSKANAERRCTKTFEDVRKEAQQSRYTKAINKRQNKKAMLESALGNAITEDPTVNCNLADNPNDQVEMPRNPDIVEPTVKPVKFKAFVSASIKPKSSKKRKLMNSASNSKLFKFKIFESEVNKDENEEEDVIPDNLIIPVKRKQNISELLDMQPSTSKAAATITSQPKIAQLKRMPSKLLNEKMKSYAKKRSNDDENKDTKNTGMHMHRYKIPKLSANKPQNTSTTQSPTRGFSRLPGMYQEPNFQNAQHPFSTRGYYPYQRAYPLHRPTSQYHMNQPQPLRLHHSMYVDAEPSFESVFPAPRYQPYNINPSMRHHYSYPGEPSPSTYPMGGIPFQNNNTLYPPMRNDLCYPRGRLNYPVRNLPPMNSQGTYPPNYPQNFLPNYPPSRQFLLSMQRLADINKQIASGSIESVGGFIQMAYAGRKYRTLKDLRERTMLSKDSLRKIFKCMCKIKRPKWRISKFYLYAYWCEISGIPQSSEFGKPLELNAAYRKVISSYAENKFLRMESLMEKTGFGKSKLKRVLKMIGRKRSTKWRLLNYRKPLIHLHRSQDM", "length": 1893 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9W6A5-1", "protein_name": "Green-sensitive opsin-1", "gene_name": "opn1mw1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNGTEGSNFYIPMSNRTGLVRSPYDYTQYYLAEPWKFKALAFYMFLLIIFGFPINVLTLVVTAQHKKLRQPLNYILVNLAFAGTIMVIFGFTVSFYCSLVGYMALGPLGCVMEGFFATLGGQVALWSLVVLAIERYIVVCKPMGSFKFSANHAMAGIAFTWFMACSCAVPPLFGWSRYLPEGMQTSCGPDYYTLNPEYNNESYVMYMFSCHFCIPVTTIFFTYGSLVCTVKAAAAQQQESESTQKAEREVTRMVILMVLGFLFAWVPYASFAAWIFFNRGAAFSAQAMAVPAFFSKTSAVFNPIIYVLLNKQFRSCMLNTLFCGKSPLGDDESSSVSTSKTEVSSVSPA", "length": 349 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q9XK79-1", "protein_name": "NADH-ubiquinone oxidoreductase chain 4L", "gene_name": "nad4L", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNLIDLILIAIYVIGISGLIFNKNNIINILIISELNLGTLGMLFVLASVELNDILGELSGLYILTFTAAESAIGLAIVVILYSKTGIINIRHLNKLKG", "length": 98 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9Y2B0-1", "protein_name": "Protein canopy homolog 2", "gene_name": "CNPY2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKGWGWLALLLGALLGTAWARRSQDLHCGACRALVDELEWEIAQVDPKKTIQMGSFRINPDGSQSVVEVPYARSEAHLTELLEEICDRMKEYGEQIDPSTHRKNYVRVVGRNGESSELDLQGIRIDSDISGTLKFACESIVEEYEDELIEFFSREADNVKDKLCSKRTDLCDHALHISHDEL", "length": 182 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9Z1X0-1", "protein_name": "C-C motif chemokine 27", "gene_name": "Ccl27", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMEGLSPASSLPLLLLLLSPAPEAALPLPSSTSCCTQLYRQPLPSRLLRRIVHMELQEADGDCHLQAVVLHLARRSVCVHPQNRSLARWLERQGKRLQGTVPSLNLVLQKKMYSHPQQQN", "length": 120 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "S4R2L0-1", "protein_name": "Secretoglobin, family 2B, member 12", "gene_name": "Scgb2b12", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGILLLLGLLITGELSFQTTEACVPFFEVYASVLSGSRVWLYHELQSFDATAEEKVALEKIQGCYREERLRNILLEPKIMEAMVASPECRSYYSLDNFRSILDFISNLLGE", "length": 112 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "W4VSP8-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r10", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSFKNVLYFQAGLGVLANMVLLLFYIFIILGHRPKPTDLISCQLTFVHIIMVLTGGDILLTDLFELLNIENDLKCKTIFYISRVMRGLSICTTCLLSVFQAVTISPNTSLMAKFKQKLKKYMACVFLCIWSFNLAFSTNRIFYVGGFTNVSETNQMQVTKSCSLLPMNIIIRGFIFTISTSRDVFLVGVMLTTSVYMVITMFRYHRQCKYLYSISHLRESPEKRATQTIVLLVSFFVVMYWVDFIISFTSDMIWMYDPLILTVQKFMMYAYPTITPLVQISSDNRIIIMLKNLQSKHQQRFFNKDIFFSL", "length": 311 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "X1WF74-1", "protein_name": "Uncharacterized protein LOC100334758 precursor", "gene_name": "si:dkey-52p2.5", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MARTSENMIGKVLFVLFLLSGPTSVLTDFHSLQILGTYIKGDTLFPQISFTFMLDDLTVGLYITERDEFIPRDNTTNEDETVSDMLDKIKNELQPLLKGTLIFQNSTESPQLFQIAWHCELLDNNKTGQMILKIAFSGSTTDEVSFYGNNFTCQCQNNMATVPLEYFQMQFKSIYYPVCMTTLGGYLVKRQVQVNRKVQPKVRLIKKVHPKSGGFRLSCLASEFYPYFINLTLLRDGQPVSDHEVTGGDLLPNGDGTYQMRKSLEIRADEREKHKYTCSAKHLDKNLDVDFEFDPSYPVKIVIPVVVLLSLVLVLTAVLIHKCMNKQAASPPEQQEPIEMGGRLRK", "length": 346 }, "evidence": [ { "id": "A0A8V1A7J1", "url": "https://omabrowser.org/oma/group/A0A8V1A7J1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "nucleic acid binding", "id": "GO:0003676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7J1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7J1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { 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"ENSGALP00010038433.1", "url": "https://www.ensembl.org/id/ENSGALP00010038433.1" } ] } }, { "isoform_ac": "A0A8V1AAH6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7V8/entry#A0A8V1AAH6-1", "sequence": { "sequence": "MAAPSAGSDMFDEIVMAEDRFHGEGYQEGYAEGSHAGAAEGRRCGALHGAKIGSEIGSYLGFALTWQHLLPKCTDEKNSKKMRALDSLIGMIQKFPYEDPTYEKLQDDLEKIRGKFKQPKTSAFIVGRVTMKILILQSAPGLVAFVF", "length": 147, "header": "tr|A0A8V1AAH6-1|A0A8V1AAH6_CHICK Computationally mapped isoform of Oral cancer overexpressed 1 OS=Gallus gallus OX=9031 GN=ORAOV1 PE=3 SV=1 CANONICAL=A0A8V1A7V8-1" }, "locus": { "chromosome": "5", "start_pos": 17114027, "end_pos": 17102976, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010062169.1", "url": "https://www.ensembl.org/id/ENSGALT00010062169.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038421.1", "url": "https://www.ensembl.org/id/ENSGALP00010038421.1" } ] } }, { "isoform_ac": "A0A8V1AAI6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7V8/entry#A0A8V1AAI6-1", "sequence": { "sequence": "MAAPSAGSDMFDEIVMAEDRFHGEGYQEGYAEGSHAGAAEGRRCGALHGAKIGSEIGSYLGFALTWQHLLPKCTDEKNSKKMRALDSLIGMIQKFPYEDPTYEKLQDDLEKIRGKFKQLLQLAACVLFSERHLGEGIGKQVQTH", "length": 144, "header": "tr|A0A8V1AAI6-1|A0A8V1AAI6_CHICK Computationally mapped isoform of Oral cancer overexpressed 1 OS=Gallus gallus OX=9031 GN=ORAOV1 PE=3 SV=1 CANONICAL=A0A8V1A7V8-1" }, "locus": { "chromosome": "5", "start_pos": 17114027, "end_pos": 17094376, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010062182.1", "url": "https://www.ensembl.org/id/ENSGALT00010062182.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038431.1", "url": "https://www.ensembl.org/id/ENSGALP00010038431.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:423142", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423142", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8W4FGL3-1", "protein_name": "LTO1 maturation factor of ABCE1", "gene_name": "LTO1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAGTQDMFDAIVMADESKKMKVLESLIGMIQKFPYDDPTYDKLHEDLDRIRGKFKQLCSLLNVQPDFKISAEGSGLAF", "length": 78 }, "evidence": [ { "id": "A0A8V1A7V8", "url": "https://omabrowser.org/oma/group/A0A8V1A7V8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q8WV07-1", "protein_name": "Protein LTO1 homolog", "gene_name": "LTO1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAGSQDIFDAIVMADERFHGEGYREGYEEGSSLGVMEGRQHGTLHGAKIGSEIGCYQGFAFAWKCLLHSCTTEKDSRKMKVLESLIGMIQKFPYDDPTYDKLHEDLDKIRGKFKQFCSLLNVQPDFKISAEGSGLSF", "length": 137 }, "evidence": [ { "id": "A0A8V1A7V8", "url": "https://omabrowser.org/oma/group/A0A8V1A7V8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1A7V8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7V8" }, { "id": "PF09811", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09811" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Essential protein Yae1 N-terminal", "eco_id": "ECO_0000259", "start_pos": 25, "end_pos": 63, "start_aa": "Gly", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A8E2-1", "uniprot_ac": "A0A8V1A8E2", "uniprot_id": "A0A8V1A8E2_CHICK", "mass": { "chemical_mass": 166723.0, "monoisotopic_mass": 166723.0 }, "refseq": {}, "gene_names": [ { "name": "ARHGAP31", "type": "recommended", "evidence": [ { "id": "A0A8V1A8E2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8E2" } ] } ], "protein_names": [ { "name": "Rho GTPase activating protein 31", "type": "synonym", "evidence": [ { "id": "A0A8V1A8E2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8E2/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A8E2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8E2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ARHGAP31", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8E2", "locus": { "chromosome": "1", "start_pos": 80822426, "end_pos": 80769368, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010025574", "url": "https://www.ensembl.org/id/ENSGALG00010025574" } ] } } ], "crossref": [ { "id": "cd04384", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04384", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000198", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000198", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008936", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008936", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051576", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051576", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZYA7", "url": "https://www.orthodb.org/?gene=A0A8V0ZYA7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A8E2", "url": "https://www.orthodb.org/?gene=A0A8V1A8E2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AAX7", "url": "https://www.orthodb.org/?gene=A0A8V1AAX7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15729", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15729", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15729:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15729:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00620", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00620", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-8980692", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8980692", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9013148", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013148", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9013149", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013149", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9013420", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013420", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZYA7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYA7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZYA7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYA7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A8E2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8E2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A8E2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8E2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AAX7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAX7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AAX7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAX7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKNKGAKQKLKRKGATSAFGCDLTEHLESSGQDVPYVLKSCAEFIETHGIVDGIYRLSGVTSNIQKLRQEFVSDQCPDLTREVYLQDIHCVGSLCKLYFRELPNPLLTYELYKKFTVRPPSVLIPNQQHGHAAGSLVTAVWVSTPMSWFLEAVSRFPEDEQLARIQNVIQELPPSHYRTLEYLIKHLTHLASFSSMTNMHTRNLALVWAPNLLRSKEIEAVGCNGDAAFLEVRVQQLVIEFILNHVDQIFSNNRKASSAESIENAPVVKNLTHPSTSLPMKLVSLEEAQARSLSASHPARKERRENSLPEIVPVTGSFFHTVVDLPDSKRKLSTKSKKWKSIFNLGRSGSESKSKLSRNGSVFVRAQKLSEKATIRPAKSMDSLCSLPVEGEDDKSRFKRTVTTGGFFVPVMKIRTGGTGSSYDLSKENEWEREGSAMAAKGNSELSGVKAPCRTSQAKCPPEQLKVFRAAEDAENEQTSPKGGLMFYTSETAAKSGFPSSLFPLEASPRHQRKALNISEPFAVSVPLRVSAVISTNSTPCRIPTRDKPSLSSLEELSSLVPESPSPSTPEGGGHMKMEQTPEKEKPSGPPPPTAASRGSLPEELVVTRKSEALETAQPAAENQETLHGQSSSTSSLRQSSEHSLTVEQAPASEVHMGPAPAVKTEQERLEMKTISPEGSCSQQEIQKAKPEEGSCVKDATEEDPANALLDPLWPEIQHELKIIEPEEELLLFPAAVPKTAPASESSSSVQTNNFSSGPEQCTTLSEQKSAGRTPQTTTQVPLFDGTSTERPDSHQNCQSDVAAQQSCASALPKLGTPLTSIAAPKNHHPVVENSMSECVTPPLEWNFRSQPEVNELPPGDEFSLSKGAHSELEKGKDSTCQMQKESDDHTRVQTQSGMPEIVAADRRDTFSSKALNGAGIQELKEGNAVSRTHDAGDQDDEDNWADNVQSLELVEPWEDHQWVTSPLHSPTFKDIQEKTIPEFQPQDQRSEAGLSIRPRFSRSLSLDSKDTVMSLWTIPFSFIDAPEQQQPCSDILPLAHEPPKKSISPTSLGKAKQDENSTCLPEEPLKTDELRYPIGKEETPAKQEEPSRIPLPGPEGKKVDVSKENTWRSKLEPSLPYQNAPDSSLQAKTTKEESSRSRDIALAEDTVTKVCSATESLQSNKDEETPRKVKTRPSSLNLDSLLPASDFLTFESLAMPSATGNFLYGQKEVKSSDSVPSLSTTCPAGGKGVSWRSPFSAHVDLDLDYLAVAHATTGRRNSAPVSVSAVRTSFMIKMCQARAVPVIPPKIQYTQIPQPLQAQNSAPQVEKKEAEAKQAGRQTQRVAWGHLEPPKSPLTEKKTKAEKENSDPAQKDSTCPWHSSLGSPLESSQSSHNPSLDAPVLRRKRTSEGETGGDNPQSSKMERPSGFSKPSYRSRPGRPQSLILFSPPFPIMDHPSSSADSRVLLSPIRSPTQTSSSSPICGDLSETSRTTPEGVMLRNKMTIPKNGQRLETSTSCFYQPQRRSVILDGRSGRQIE", "length": 1521, "header": "tr|A0A8V1A8E2-1|A0A8V1A8E2_CHICK Isoform 1 of Rho GTPase activating protein 31 OS=Gallus gallus OX=9031 GN=ARHGAP31 PE=1 SV=1 CANONICAL=A0A8V1A8E2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZYA7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8E2/entry#A0A8V0ZYA7-1", "sequence": { "sequence": "MKNKGAKQKLKRKGATSAFGCDLTEHLESSGQDVPYVLKSCAEFIETHGIVDGIYRLSGVTSNIQKLRQEFVSDQCPDLTREVYLQDIHCVGSLCKLYFRELPNPLLTYELYKKFTEAVSRFPEDEQLARIQNVIQELPPSHYRTLEYLIKHLTHLASFSSMTNMHTRNLALVWAPNLLRSKEIEAVGCNGDAAFLEVRVQQLVIEFILNHVDQIFSNNRKASSAESIENAPVVKNLTHPSTSLPMKLVSLEEAQARSLSASHPARKERRENSLPEIVPVTGSFFHTVVDLPDSKRKLSTKSKKWKSIFNLGRSGSESKSKLSRNGSVFVRAQKLSGEDDKSRFKRTVTTGGFFVPVMKIRTGGTGSSYDLSKENEWEREGSAMAAKGNSELSGVKAPCRTSQAKCPPEQLKVFRAAEDAENEQTSPKGGLMFYTSETAAKSGFPSSLFPLEASPRHQRKALNISEPFAVSVPLRVSAVISTNSTPCRIPTRDKPSLSSLEELSSLVPESPSPSTPEGGGHMKMEQTPEKEKPSGPPPPTAASRGSLPEELVVTRKSEALETAQPAAENQETLHGQSSSTSSLRQSSEHSLTVEQAPASEVHMGPAPAVKTEQERLEMKTISPEGSCSQQEIQKAKPEEGSCVKDATEEDPANALLDPLWPEIQHELKIIEPEEELLLFPAAVPKTAPASESSSSVQTNNFSSGPEQCTTLSEQKSAGRTPQTTTQVPLFDGTSTERPDSHQNCQSDVAAQQSCASALPKLGTPLTSIAAPKNHHPVVENSMSECVTPPLEWNFRSQPEVNELPPGDEFSLSKGAHSELEKGKDSTCQMQKESDDHTRVQTQSGMPEIVAADRRDTFSSKALNGAGIQELKEGNAVSRTHDAGDQDDEDNWADNVQSLELVEPWEDHQWVTSPLHSPTFKDIQEKTIPEFQPQDQRSEAGLSIRPRFSRSLSLDSKDTVMSLWTIPFSFIDAPEQQQPCSDILPLAHEPPKKSISPTSLGKAKQDENSTCLPEEPLKTDELRYPIGKEETPAKQEEPSRIPLPGPEGKKVDVSKENTWRSKLEPSLPYQNAPDSSLQAKTTKEESSRSRDIALAEDTVTKVCSATESLQSNKDEETPRKVKTRPSSLNLDSLLPASDFLTFESLAMPSATGNFLYGQKEVKSSDSVPSLSTTCPAGGKGVSWRSPFSAHVDLDLDYLAVAHATTGRRNSAPVSVSAVRTSFMIKMCQARAVPVIPPKIQYTQIPQPLQAQNSAPQVEKKEAEAKQAGRQTQRVAWGHLEPPKSPLTEKKTKAEKENSDPAQKDSTCPWHSSLGSPLESSQSSHNPSLDAPVLRRKRTSEGETGGDNPQSSKMERPSGFSKPSYRSRPGRPQSLILFSPPFPIMDHPSSSADSRVLLSPIRSPTQTSSSSPICGDLSETSRTTPEGVMLRNKMTIPKNGQRLETSTSCFYQPQRRSVILDGRSGRQIE", "length": 1467, "header": "tr|A0A8V0ZYA7-1|A0A8V1A8E2_CHICK Computationally mapped isoform of Rho GTPase activating protein 31 OS=Gallus gallus OX=9031 GN=ARHGAP31 PE=1 SV=1 CANONICAL=A0A8V1A8E2-1" }, "locus": { "chromosome": "1", "start_pos": 80822099, "end_pos": 80769567, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010062403.1", "url": "https://www.ensembl.org/id/ENSGALT00010062403.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038578.1", "url": "https://www.ensembl.org/id/ENSGALP00010038578.1" } ] } }, { "isoform_ac": "A0A8V1A8E2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8E2/entry#A0A8V1A8E2-1", "sequence": { "sequence": "MKNKGAKQKLKRKGATSAFGCDLTEHLESSGQDVPYVLKSCAEFIETHGIVDGIYRLSGVTSNIQKLRQEFVSDQCPDLTREVYLQDIHCVGSLCKLYFRELPNPLLTYELYKKFTVRPPSVLIPNQQHGHAAGSLVTAVWVSTPMSWFLEAVSRFPEDEQLARIQNVIQELPPSHYRTLEYLIKHLTHLASFSSMTNMHTRNLALVWAPNLLRSKEIEAVGCNGDAAFLEVRVQQLVIEFILNHVDQIFSNNRKASSAESIENAPVVKNLTHPSTSLPMKLVSLEEAQARSLSASHPARKERRENSLPEIVPVTGSFFHTVVDLPDSKRKLSTKSKKWKSIFNLGRSGSESKSKLSRNGSVFVRAQKLSEKATIRPAKSMDSLCSLPVEGEDDKSRFKRTVTTGGFFVPVMKIRTGGTGSSYDLSKENEWEREGSAMAAKGNSELSGVKAPCRTSQAKCPPEQLKVFRAAEDAENEQTSPKGGLMFYTSETAAKSGFPSSLFPLEASPRHQRKALNISEPFAVSVPLRVSAVISTNSTPCRIPTRDKPSLSSLEELSSLVPESPSPSTPEGGGHMKMEQTPEKEKPSGPPPPTAASRGSLPEELVVTRKSEALETAQPAAENQETLHGQSSSTSSLRQSSEHSLTVEQAPASEVHMGPAPAVKTEQERLEMKTISPEGSCSQQEIQKAKPEEGSCVKDATEEDPANALLDPLWPEIQHELKIIEPEEELLLFPAAVPKTAPASESSSSVQTNNFSSGPEQCTTLSEQKSAGRTPQTTTQVPLFDGTSTERPDSHQNCQSDVAAQQSCASALPKLGTPLTSIAAPKNHHPVVENSMSECVTPPLEWNFRSQPEVNELPPGDEFSLSKGAHSELEKGKDSTCQMQKESDDHTRVQTQSGMPEIVAADRRDTFSSKALNGAGIQELKEGNAVSRTHDAGDQDDEDNWADNVQSLELVEPWEDHQWVTSPLHSPTFKDIQEKTIPEFQPQDQRSEAGLSIRPRFSRSLSLDSKDTVMSLWTIPFSFIDAPEQQQPCSDILPLAHEPPKKSISPTSLGKAKQDENSTCLPEEPLKTDELRYPIGKEETPAKQEEPSRIPLPGPEGKKVDVSKENTWRSKLEPSLPYQNAPDSSLQAKTTKEESSRSRDIALAEDTVTKVCSATESLQSNKDEETPRKVKTRPSSLNLDSLLPASDFLTFESLAMPSATGNFLYGQKEVKSSDSVPSLSTTCPAGGKGVSWRSPFSAHVDLDLDYLAVAHATTGRRNSAPVSVSAVRTSFMIKMCQARAVPVIPPKIQYTQIPQPLQAQNSAPQVEKKEAEAKQAGRQTQRVAWGHLEPPKSPLTEKKTKAEKENSDPAQKDSTCPWHSSLGSPLESSQSSHNPSLDAPVLRRKRTSEGETGGDNPQSSKMERPSGFSKPSYRSRPGRPQSLILFSPPFPIMDHPSSSADSRVLLSPIRSPTQTSSSSPICGDLSETSRTTPEGVMLRNKMTIPKNGQRLETSTSCFYQPQRRSVILDGRSGRQIE", "length": 1521, "header": "tr|A0A8V1A8E2-1|A0A8V1A8E2_CHICK Isoform 1 of Rho GTPase activating protein 31 OS=Gallus gallus OX=9031 GN=ARHGAP31 PE=1 SV=1 CANONICAL=A0A8V1A8E2-1" }, "locus": { "chromosome": "1", "start_pos": 80822099, "end_pos": 80769567, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010062401.1", "url": "https://www.ensembl.org/id/ENSGALT00010062401.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038576.1", "url": "https://www.ensembl.org/id/ENSGALP00010038576.1" } ] } }, { "isoform_ac": "A0A8V1AAX7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8E2/entry#A0A8V1AAX7-1", "sequence": { "sequence": 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"length": 1458, "header": "tr|A0A8V1AAX7-1|A0A8V1AAX7_CHICK Computationally mapped isoform of Rho GTPase activating protein 31 OS=Gallus gallus OX=9031 GN=ARHGAP31 PE=1 SV=1 CANONICAL=A0A8V1A8E2-1" }, "locus": { "chromosome": "1", "start_pos": 80822099, "end_pos": 80801758, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010062396.1", "url": "https://www.ensembl.org/id/ENSGALT00010062396.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038574.1", "url": "https://www.ensembl.org/id/ENSGALP00010038574.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 569, "start_aa": "Thr", "end_pos": 569, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr569", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 594, "start_aa": "Thr", "end_pos": 594, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr594", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-GGA-8980692", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8980692", "resource": "Reactome", "description": "RHOA GTPase cycle" }, { "id": "R-GGA-9013148", "name": "", "url": 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"database": "UniProtKB", "id": "A0A8V1A8E2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8E2" } ], "pmid": "" }, { "name": "small GTPase-mediated signal transduction", "id": "GO:0007264", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007264", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A8E2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8E2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "lamellipodium", "id": "GO:0030027", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030027", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A8E2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8E2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1061, "end_pos": 1063, "annotation": "n_glycosylation_sequon" }, { "start_pos": 270, "end_pos": 272, "annotation": "n_glycosylation_sequon" }, { "start_pos": 359, "end_pos": 361, "annotation": "n_glycosylation_sequon" }, { "start_pos": 517, "end_pos": 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"XP_004941528", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004941528" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052536.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004941528", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004941528" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A8G2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8G2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RASSF7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8G2", "locus": { "chromosome": "5", "start_pos": 15487836, "end_pos": 15523002, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010025580", "url": "https://www.ensembl.org/id/ENSGALG00010025580" } ] } } ], "crossref": [ { "id": "A0A8V1A8G2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A8G2", "database": 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"url": "https://www.orthodb.org/?gene=A0A8V1A5W5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A8G2", "url": "https://www.orthodb.org/?gene=A0A8V1A8G2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BTN3", "url": "https://www.orthodb.org/?gene=E1BTN3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15286", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15286", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15286:SF11", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15286:SF11", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00788", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00788", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004941528", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004941528", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZYC3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYC3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZYC3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYC3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZYC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYC8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZYC8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYC8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A3J1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3J1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A3J1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3J1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A5U8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5U8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A5U8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5U8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A5W5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5W5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A5W5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5W5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A8G2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8G2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A8G2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8G2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BTN3", "url": "https://www.uniprot.org/uniprotkb/E1BTN3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BTN3-1", "url": "https://www.uniprot.org/uniprotkb/E1BTN3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MELKVWVDGIQRVVCGVSEQTTCQEVVIALARAIGQTGRYVLVQKLREKERQLLPLECPLESLAKCGQYANDVQFILRRTGPSVTERPSSEGAPQAPERTFIRASLPIKPRALSTDVPRPREPRKSMTFNLGPMGSVDPYAKSRWRQHAWEGMDLKDGGAGQPSKEELFKTVLRQQEQLHSLEAHGDTLETDLRLWEHGRASSQEDEILYLEHLVRRNDTELGEEEFWQSELRLEKECERERQERVRSLRASLEEYTQRIYELSARTEALQKEIQWEMAERAKRGKEIPVPSPTDLEDMAAKMKRDLEAKVKQGTQLENNLASVEKALEEAERSLQAQNQELEELNKELRQCNLQQFIQQTGATVTVGQARSEEDAQPELSPRELPACRRNGGFPPTGADSPPCASTKQLLSHPRTLPEPLVPSLNPEVLYKQWMKLISTEKAAVSGMKHGSFLIMHSSSTEHFRTGREGDGTWLQI", "length": 477, "header": "tr|A0A8V1A8G2-1|A0A8V1A8G2_CHICK Isoform 1 of Ras association domain family member 7 OS=Gallus gallus OX=9031 GN=RASSF7 PE=4 SV=1 CANONICAL=A0A8V1A8G2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZYC3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8G2/entry#A0A8V0ZYC3-1", "sequence": { "sequence": "MELKVWVDGIQRVVCGVSEQTTCQEVVIALARAIGQTGRYVLVQKLREKERQLLPLECPLESLAKCGQYANDVQFILRRTGPSVTERPSSEGAPQAPERTFIRASLPIKPRALSTDVPRPREPRKSMTFNLGPMGSVDPYAKSRWRQHAWEGMDLKDGGAGQPSKEELFKTVLRQQEQLHSLEAHGDTLETDLRLWEHGRASSQEDEILYLEHLVRRNDTELGEEEFWQSELRLEKECERERQERVRSLRASLEEYTQRIYELSARTEALQKEIQWEMAERAKRGKEIPVPSPTDLEDMAAKMKRDLEAKVKQGTQLENNLASVEKALEEAERSLQAQNQELEELNKELRQCNLQQFIQQTGATVTVGQARSEEDAQPELSPRELPACRRNGGFPPTGADSPPCASTKQLLSHPRTLPEPLVPSLNPEGAYVPAGPHAPGRGDGFAVRNGAAESE", "length": 455, "header": "tr|A0A8V0ZYC3-1|A0A8V1A8G2_CHICK Computationally mapped isoform of Ras association domain family member 7 OS=Gallus gallus OX=9031 GN=RASSF7 PE=4 SV=1 CANONICAL=A0A8V1A8G2-1" }, "locus": { "chromosome": "5", "start_pos": 15495434, "end_pos": 15491212, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010062419.1", "url": "https://www.ensembl.org/id/ENSGALT00010062419.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038593.1", "url": "https://www.ensembl.org/id/ENSGALP00010038593.1" } ] } }, { "isoform_ac": "A0A8V0ZYC8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8G2/entry#A0A8V0ZYC8-1", "sequence": { "sequence": "MELKVWVDGIQRVVCGVSEQTTCQEVVIALARAIGQTGRYVLVQKLREKERQLLPLECPLESLAKCGQYANDVQFILRRTGPSVTERPSSEGAPQAPERTFIRASLPIKPRALSTDVPRPREPRKSMTFNLGPMGSVDPYAKSRWRQHAWEGMDLKDGGAGQPSKEELFKTVLRQQEQLHSLEAHGDTLETDLRLWEHGRASSQEDEILYLEHLVRRNDTELGEEEFWQSELRLEKECERERQERVRSLRASLEEYTQRIYELSARTEALQKEIQWEMAERAKRGKEIPVPSPTDLEDMAAKMKRDLEAKVKQGTQLENNLASVEKALEEAERSLQAQNQELEELNKELRQCNLQQFIQQTGATVTVGQARSEEDAQPELSPRELPACRRNGVLYKQWMKLISTEKAAVSGMKHGSFLIMHSSSTEHFRTGREGDGTWLQI", "length": 441, "header": "tr|A0A8V0ZYC8-1|A0A8V1A8G2_CHICK Computationally mapped isoform of Ras association domain family member 7 OS=Gallus gallus OX=9031 GN=RASSF7 PE=4 SV=1 CANONICAL=A0A8V1A8G2-1" }, "locus": { "chromosome": "5", "start_pos": 15495434, "end_pos": 15488865, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010062426.1", "url": "https://www.ensembl.org/id/ENSGALT00010062426.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038598.1", "url": "https://www.ensembl.org/id/ENSGALP00010038598.1" } ] } }, { "isoform_ac": "A0A8V1A3J1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8G2/entry#A0A8V1A3J1-1", "sequence": { "sequence": "MELKVWVDGIQRVVCGVSEQTTCQEVVIALARAIGQTGRYVLVQKLREKERQLLPLECPLESLAKCGQYANDVQFILRRTGPSVTERPSSEGAPQAPERTFIRASLPIKPRALSTDVPRPREPRKSMTFNLGPMGSVDPYAKSRWRQHAWEGMDLKDGGAGQPSKEELFKTVLRQQEQLHSLEAHGDTLETDLRLWEHGRASSQEDEILYLEHLVRRNDTELGEEEFWQSELRLEKECERERQERVRSLRASLEEYTQRIYELSARTEALQKEIQWEMAERAKRGKEIPVPSPTDLEDMAAKMKRDLEAKVKQGTQLENNLASVEKALEEAERSLQSYQPGRASGGRRAQPVDDWLPCKCSCINKTIFPKYILHFLLLYITNGCGWPDRVFLQTVR", "length": 396, "header": "tr|A0A8V1A3J1-1|A0A8V1A8G2_CHICK Computationally mapped isoform of Ras association domain family member 7 OS=Gallus gallus OX=9031 GN=RASSF7 PE=4 SV=1 CANONICAL=A0A8V1A8G2-1" }, "locus": { "chromosome": "5", "start_pos": 15495434, "end_pos": 15490608, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010062415.1", "url": "https://www.ensembl.org/id/ENSGALT00010062415.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038590.1", "url": "https://www.ensembl.org/id/ENSGALP00010038590.1" } ] } }, { "isoform_ac": "A0A8V1A5U8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8G2/entry#A0A8V1A5U8-1", "sequence": { "sequence": "MELKVWVDGIQRVVCGVSEQTTCQEVVIALARAIGQTGRYVLVQKLREKERQLLPLECPLESLAKCGQYANDVQFILRRTGPSVTERPSSEGAPQAPERTFIRASLPIKPRALSTDVPRPREPRKSMTFNLGPMGSVDPYAKSRWRQHAWEGMDLKDGGAGQPSKEELFKTVLRQQEQLHSLEAHGDTLETDLRLWEHGRASSQEDEILYLEHLVRRNDTELGEEEFWQSELRLEKECERERQERVRSLRASLEEYTQRIYELSARTEALQKEIQWEMAERAKRGKEIPVPSPTDLEDMAAKMKRDLEAKVKQGTQLENNLASVEKALEEAERSLQAQNQELEELNKELRQCNLQQFIQQTGATVTVGQARSEEDAQPELSPRELPACRRNGGQHAASAAACPAPPNLLVGLAPSSSLSGLLAAGFVAECDTGLGTGLVALPL", "length": 443, "header": "tr|A0A8V1A5U8-1|A0A8V1A8G2_CHICK Computationally mapped isoform of Ras association domain family member 7 OS=Gallus gallus OX=9031 GN=RASSF7 PE=4 SV=1 CANONICAL=A0A8V1A8G2-1" }, "locus": { "chromosome": "5", "start_pos": 15495434, "end_pos": 15491575, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010062407.1", "url": "https://www.ensembl.org/id/ENSGALT00010062407.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038582.1", "url": "https://www.ensembl.org/id/ENSGALP00010038582.1" } ] } }, { "isoform_ac": "A0A8V1A5W5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8G2/entry#A0A8V1A5W5-1", "sequence": { "sequence": "MELKVWVDGIQRVVCGVSEQTTCQEVVIALARAIGQTGRYVLVQKLREKERQLLPLECPLESLAKCGQYANDVQFILRRTGPSVTERPSSEGAPQAPERTFIRASLPIKPRALSTDVPRPREPRKSMTFNLGPMGSVDPYAKSRWRQHAWEGMDLKDGGAGQPSKEELFKTVLRQQEQLHSLEAHGDTLETDLRLWEHGRASSQEDEILYLEHLVRRNDTELGEEEFWQSELRLEKECERERQERVRSLRASLEEYTQRIYELSARTEALQKEIQWEMAERAKRGKEIPVPSPTDLEDMAAKMKRDLEAKVKQGTQLENNLASVEKALEEAERSLQAQNQELEELNKELRQCNLQQFIQQTGATVTVGQARSEEDAQPELSPRELPACRRNGVISTRQSIWR", "length": 402, "header": "tr|A0A8V1A5W5-1|A0A8V1A8G2_CHICK Computationally mapped isoform of Ras association domain family member 7 OS=Gallus gallus OX=9031 GN=RASSF7 PE=4 SV=1 CANONICAL=A0A8V1A8G2-1" }, "locus": { "chromosome": "5", "start_pos": 15495434, "end_pos": 15490759, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010062424.1", "url": "https://www.ensembl.org/id/ENSGALT00010062424.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038597.1", "url": "https://www.ensembl.org/id/ENSGALP00010038597.1" } ] } }, { "isoform_ac": "A0A8V1A8G2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8G2/entry#A0A8V1A8G2-1", "sequence": { "sequence": "MELKVWVDGIQRVVCGVSEQTTCQEVVIALARAIGQTGRYVLVQKLREKERQLLPLECPLESLAKCGQYANDVQFILRRTGPSVTERPSSEGAPQAPERTFIRASLPIKPRALSTDVPRPREPRKSMTFNLGPMGSVDPYAKSRWRQHAWEGMDLKDGGAGQPSKEELFKTVLRQQEQLHSLEAHGDTLETDLRLWEHGRASSQEDEILYLEHLVRRNDTELGEEEFWQSELRLEKECERERQERVRSLRASLEEYTQRIYELSARTEALQKEIQWEMAERAKRGKEIPVPSPTDLEDMAAKMKRDLEAKVKQGTQLENNLASVEKALEEAERSLQAQNQELEELNKELRQCNLQQFIQQTGATVTVGQARSEEDAQPELSPRELPACRRNGGFPPTGADSPPCASTKQLLSHPRTLPEPLVPSLNPEVLYKQWMKLISTEKAAVSGMKHGSFLIMHSSSTEHFRTGREGDGTWLQI", "length": 477, "header": "tr|A0A8V1A8G2-1|A0A8V1A8G2_CHICK Isoform 1 of Ras association domain family member 7 OS=Gallus gallus OX=9031 GN=RASSF7 PE=4 SV=1 CANONICAL=A0A8V1A8G2-1" }, "locus": { "chromosome": "5", "start_pos": 15495434, "end_pos": 15488865, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010062423.1", "url": "https://www.ensembl.org/id/ENSGALT00010062423.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038596.1", "url": "https://www.ensembl.org/id/ENSGALP00010038596.1" } ] } }, { "isoform_ac": "E1BTN3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8G2/entry#E1BTN3-1", "sequence": { "sequence": "MELKVWVDGIQRVVCGVSEQTTCQEVVIALARAIGQTGRYVLVQKLREKERQLLPLECPLESLAKCGQYANDVQFILRRTGPSVTERPSSEGAPQAPERTFIRASLPIKPRALSTDVPRPREPRKSMTFNLGPMGSVDPYAKSRWRQHAWEGMDLKDGGAGQPSKEELFKTVLRQQEQLHSLEAHGDTLETDLRLWEHGRASSQEDEILYLEHLVRRNDTELGEEEFWQSELRLEKECERERQERVRSLRASLEEYTQRIYELSARTEALQKEIQWEMAERAKRGKEIPVPSPTDLEDMAAKMKRDLEAKVKQGTQLENNLASVEKALEEAERSLQAQNQELEELNKELRQCNLQQFIQQTGATVTVGQARSEEDAQPELSPRELPACRRNGGFPPTGADSPPCASTKQLLSHPRTLPEPLVPSLNPEVISTRQSIWR", "length": 438, "header": "tr|E1BTN3-1|A0A8V1A8G2_CHICK Computationally mapped isoform of Ras association domain family member 7 OS=Gallus gallus OX=9031 GN=RASSF7 PE=4 SV=5 CANONICAL=A0A8V1A8G2-1" }, "locus": { "chromosome": "5", "start_pos": 15495434, "end_pos": 15490759, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010062411.1", "url": "https://www.ensembl.org/id/ENSGALT00010062411.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038586.1", "url": "https://www.ensembl.org/id/ENSGALP00010038586.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 366, "start_aa": "Thr", "end_pos": 366, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr366", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:423107", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423107", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6A120-1", "protein_name": "Ras association domain-containing protein 7", "gene_name": "Rassf7", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVLELVAMELKVWVDGIQRVVCGVSEQTTCQEVVIALAQAIGQTGRFVLVQRLREKERQLLPQECPVGAQATCGQFANDVQFVLRRTGPSLSGRPSSDNCPPPERCPVRASLPPKAGATPGREPRKPLTFNLGCPRLVPSPSVPEPTALVGPIPDCFADLQSLELRIQRNTEELGHEAFWEQELQREQAREQEGQARLQALSAATAEHAARLEALDAQACALEAELRLAAEAPGPPSATASAAERLRQDLAIQERHSLEMQGTLALVSQALEAAEHALQAQAQELEELNRELRQCNLQQFIQQTGAALPPPPQLDRTSTQVRDLPPPTREELLQGVPQSHILVSSLSPEVPPMRQSSWR", "length": 359 }, "evidence": [ { "id": "A0A8V1A8G2", "url": "https://omabrowser.org/oma/group/A0A8V1A8G2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A9J7JWB5-1", "protein_name": "Ras association domain-containing protein 7", "gene_name": "Rassf7", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MVLELVVMELKVWVDGIQRVVCGVSEQTTCQEVVIALAQAIGQTGRFVLVQRLREKERQLLPQECPVGAQATCGQFASDVQFVLRRTGPSLSGRPSSDNCPPPERCPVRASLPPKPWAAPGREPHKALTFNPGCPKLVPSSSIPESTTLVGPTPDCFADLQGLELRIQRNAEELGHEAFWEQELRREQAREREGQARLQALSAATAEHAARLEALDAQACALEAELRLAAEAPGPPSATASATERLRQDLAIQERHSMEMQGTLALVSRALEAAEHALQAQAQELEELNRELRQCNLQQFIQQTGAAVPPPPQLDRTIPSPQDLPTRDEPLQGVPQSHILVSSLSPEGMFLSLPLSPIHGKGPALVSAHSACVFLTVPPMRQSSWR", "length": 386 }, "evidence": [ { "id": "A0A8V1A8G2", "url": "https://omabrowser.org/oma/group/A0A8V1A8G2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q02833-1", "protein_name": "Ras association domain-containing protein 7", "gene_name": "RASSF7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLLGLAAMELKVWVDGIQRVVCGVSEQTTCQEVVIALAQAIGQTGRFVLVQRLREKERQLLPQECPVGAQATCGQFASDVQFVLRRTGPSLAGRPSSDSCPPPERCLIRASLPVKPRAALGCEPRKTLTPEPAPSLSRPGPAAPVTPTPGCCTDLRGLELRVQRNAEELGHEAFWEQELRREQAREREGQARLQALSAATAEHAARLQALDAQARALEAELQLAAEAPGPPSPMASATERLHQDLAVQERQSAEVQGSLALVSRALEAAERALQAQAQELEELNRELRQCNLQQFIQQTGAALPPPPRPDRGPPGTQGPLPPAREESLLGAPSESHAGAQPRPRGGPHDAELLEVAAAPAPEWCPLAAQPQAL", "length": 373 }, "evidence": [ { "id": "A0A8V1A8G2", "url": "https://omabrowser.org/oma/group/A0A8V1A8G2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9DD19-1", "protein_name": "Ras association domain-containing protein 7", "gene_name": "Rassf7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVLELVAMELKVWVDGIQRVVCGVSEQTTCQEVVIALAQAIGQTGRFVLVQRLREKERQLLPQECPVGAQATCGQFANDVQFVLRRTGPSLSGRPSSDNCPPPERCPVRASLPPKPSAIPGREPRKALTFNLRCPKLVPSPSIPEPAALVGPIPDGFADLQDLELRIQRNTEELGHEAFWEQELQREQAREREGQARLQALSAATAEHAARLEALDAQACALEAELRLAAEAPGPPSATASAAERLRQDLATQERHSLEMQGTLALVSQALEAAEHALQAQAQELEELNRELRQCNLQQFIQQTGAALPPPPPQLDRTIPSTQDLLSPNRGELQGVPQSHILVSSLSPEVPPMRQSSWR", "length": 359 }, "evidence": [ { "id": "A0A8V1A8G2", "url": "https://omabrowser.org/oma/group/A0A8V1A8G2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A8G2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8G2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "centriolar satellite", "id": "GO:0034451", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034451", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A8G2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8G2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 218, "end_pos": 220, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1A8G2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8G2" }, { "id": "PS50200", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50200" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ras-associating", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 82, "start_aa": "Met", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 366 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 218, "end_pos": 220 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A8I2-1", "uniprot_ac": "A0A8V1A8I2", "uniprot_id": "A0A8V1A8I2_CHICK", "mass": { "chemical_mass": 29024.0, "monoisotopic_mass": 29024.0 }, "refseq": { "ac": "XP_015146789", "name": "ERI1 exoribonuclease 3 isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015146789" }, "gene_names": [ { "name": "ERI3", "type": "recommended", "evidence": [ { "id": "A0A8V1A8I2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8I2" } ] }, { "name": "ERI3", "type": "synonym", "evidence": [ { "id": "XP_015146789", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015146789" } ] } ], "protein_names": [ { "name": "ERI1 exoribonuclease 3", "type": "recommended", "evidence": [ { "id": "A0A8V1A8I2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8I2/entry#names_and_taxonomy" } ] }, { "name": "ERI1 exoribonuclease 3 isoform X3", "type": "synonym", "evidence": [ { "id": "XP_015146789", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015146789" } ] }, { "name": "Prion interactor 1", "type": "synonym", "evidence": [ { "id": "A0A8V1A8I2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8I2/entry#names_and_taxonomy" } ] }, { "name": "Prion protein-interacting protein", "type": "synonym", "evidence": [ { "id": "A0A8V1A8I2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8I2/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052539.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015146789.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015146789", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015146789" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A8I2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8I2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ERI3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8I2", "locus": { "chromosome": "8", "start_pos": 20142136, "end_pos": 20239404, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010025595", "url": "https://www.ensembl.org/id/ENSGALG00010025595" } ] } } ], "crossref": [ { "id": "A0A8V1A8I2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A8I2", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd06133", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06133", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "424579", "url": "https://www.ncbi.nlm.nih.gov/gene/424579", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR012337", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012337", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013520", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013520", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036397", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036397", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047201", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047201", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051274", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051274", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:424579", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424579", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GSHHLGF", "url": "https://omabrowser.org/oma/group/GSHHLGF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZYE6", "url": "https://www.orthodb.org/?gene=A0A8V0ZYE6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A8I2", "url": "https://www.orthodb.org/?gene=A0A8V1A8I2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AB12", "url": "https://www.orthodb.org/?gene=A0A8V1AB12", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23044", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23044", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23044:SF61", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23044:SF61", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00929", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00929", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015146789", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015146789", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZYE6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYE6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZYE6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYE6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A8I2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8I2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A8I2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8I2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AB12", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB12", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AB12-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB12-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MIALLHTGAAKFPQHFVPRARQAVHLLLPAALLKGYSSVISRKLASHGFGASMAAMSSFPPQRYHYFLVLDFEATCDKPQIHPQEIIEFPILKLNGRTMEIESTFHMYVQPVVHPQLTPFCTELTGIIQGMVDGQPSLQQVLERVDEWMAKEGLLDPSVKSIFVTCGDWDLKVMLPGQCQYLGLPVADYFKQWINLKKAYSFAMGSWPKNGLLDMNKGLNLQHIGRPHSGIDDCKNIANIMKTLAHRGFIFKQTSKPF", "length": 258, "header": "tr|A0A8V1A8I2-1|A0A8V1A8I2_CHICK Isoform 1 of ERI1 exoribonuclease 3 OS=Gallus gallus OX=9031 GN=ERI3 PE=1 SV=1 CANONICAL=A0A8V1A8I2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZYE6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8I2/entry#A0A8V0ZYE6-1", "sequence": { "sequence": "MFNDSTPPYWSSKVSPALRSKGETSRAPAPPCCSSQRRYHYFLVLDFEATCDKPQIHPQEIIEFPILKLNGRTMEIESTFHMYVQPVVHPQLTPFCTELTGIIQGMVDGQPSLQQVLERVDEWMAKEGLLDPSVKSIFVTCGDWDLKVMLPGQCQYLGLPVADYFKQWINLKKAYSFAMGSWPKNGLLDMNKGLNLQHIGRPHSGIDDCKNIANIMKTLAHRGFIFKQTSKPF", "length": 233, "header": "tr|A0A8V0ZYE6-1|A0A8V1A8I2_CHICK Computationally mapped isoform of ERI1 exoribonuclease 3 OS=Gallus gallus OX=9031 GN=ERI3 PE=1 SV=1 CANONICAL=A0A8V1A8I2-1" }, "locus": { "chromosome": "8", "start_pos": 20231072, "end_pos": 20143608, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010062449.1", "url": "https://www.ensembl.org/id/ENSGALT00010062449.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038614.1", "url": "https://www.ensembl.org/id/ENSGALP00010038614.1" } ] } }, { "isoform_ac": "A0A8V1A8I2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8I2/entry#A0A8V1A8I2-1", "sequence": { "sequence": "MIALLHTGAAKFPQHFVPRARQAVHLLLPAALLKGYSSVISRKLASHGFGASMAAMSSFPPQRYHYFLVLDFEATCDKPQIHPQEIIEFPILKLNGRTMEIESTFHMYVQPVVHPQLTPFCTELTGIIQGMVDGQPSLQQVLERVDEWMAKEGLLDPSVKSIFVTCGDWDLKVMLPGQCQYLGLPVADYFKQWINLKKAYSFAMGSWPKNGLLDMNKGLNLQHIGRPHSGIDDCKNIANIMKTLAHRGFIFKQTSKPF", "length": 258, "header": "tr|A0A8V1A8I2-1|A0A8V1A8I2_CHICK Isoform 1 of ERI1 exoribonuclease 3 OS=Gallus gallus OX=9031 GN=ERI3 PE=1 SV=1 CANONICAL=A0A8V1A8I2-1" }, "locus": { "chromosome": "8", "start_pos": 20231065, "end_pos": 20143608, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010062452.1", "url": "https://www.ensembl.org/id/ENSGALT00010062452.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038617.1", "url": "https://www.ensembl.org/id/ENSGALP00010038617.1" } ] } }, { "isoform_ac": "A0A8V1AB12-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8I2/entry#A0A8V1AB12-1", "sequence": { "sequence": "MIALLHTGAAKFPQHFVPRARQAVHLLLPAALLKGYSSVISRKLASHGFGASMAAMSSFPPQRYHYFLVLDFEATCDKPQIHPQEIIEFPILKLNGRTMEIESTFHMYVQPVVHPQLTPFCTELTGIIQGMVDGQPSLQQVLERVDEWMAKEGLLDPSVKSIFVTCGDWDLKVMLPGQCQYLGLPVADYFKQWINLKKAYSFAMGSWPKNGLLDMNKGLNLQHIGRPHSGIAFVVSWL", "length": 238, "header": "tr|A0A8V1AB12-1|A0A8V1AB12_CHICK Computationally mapped isoform of ERI1 exoribonuclease 3 OS=Gallus gallus OX=9031 GN=ERI3 PE=1 SV=1 CANONICAL=A0A8V1A8I2-1" }, "locus": { "chromosome": "8", "start_pos": 20231065, "end_pos": 20165778, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010062445.1", "url": "https://www.ensembl.org/id/ENSGALT00010062445.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038610.1", "url": "https://www.ensembl.org/id/ENSGALP00010038610.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:424579", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424579", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "O43414-1", "protein_name": "ERI1 exoribonuclease 3", "gene_name": "ERI3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATASPAADGGRGRPWEGGLVSWPPAPPLTLPWTWMGPSWGQHPGHWGFPALTEPSASPAAGLGIFEVRRVLDASGCSMLAPLQTGAARFSSYLLSRARKVLGSHLFSPCGVPEFCSISTRKLAAHGFGASMAAMVSFPPQRYHYFLVLDFEATCDKPQIHPQEIIEFPILKLNGRTMEIESTFHMYVQPVVHPQLTPFCTELTGIIQAMVDGQPSLQQVLERVDEWMAKEGLLDPNVKSIFVTCGDWDLKVMLPGQCQYLGLPVADYFKQWINLKKAYSFAMGCWPKNGLLDMNKGLSLQHIGRPHSGIDDCKNIANIMKTLAYRGFIFKQTSKPF", "length": 337 }, "evidence": [ { "id": "A0A8V1A8I2", "url": "https://omabrowser.org/oma/group/A0A8V1A8I2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8W566-1", "protein_name": "Uncharacterized exonuclease domain-containing protein At3g15140", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": 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"o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A8T7-1", "uniprot_ac": "A0A8V1A8T7", "uniprot_id": "A0A8V1A8T7_CHICK", "mass": { "chemical_mass": 51714.0, "monoisotopic_mass": 51714.0 }, "refseq": {}, "gene_names": [ { "name": "IGSF11", "type": "recommended", "evidence": [ { "id": "A0A8V1A8T7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8T7" } ] } ], "protein_names": [ { "name": "Immunoglobulin superfamily member 11", "type": "synonym", "evidence": [ { "id": "A0A8V1A8T7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8T7/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A8T7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8T7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "IGSF11", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8T7", "locus": { "chromosome": "1", "start_pos": 80984840, "end_pos": 80862029, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010025653", "url": "https://www.ensembl.org/id/ENSGALG00010025653" } ] } } ], "crossref": [ { "id": "A0A8V1A8T7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A8T7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000015084", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000015084", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "418346", "url": "https://www.ncbi.nlm.nih.gov/gene/418346", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013106", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013106", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042758", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042758", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:418346", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418346", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CKGSSSW", "url": "https://omabrowser.org/oma/group/CKGSSSW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A140T8H1", "url": "https://www.orthodb.org/?gene=A0A140T8H1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2TZX4", "url": "https://www.orthodb.org/?gene=A0A3Q2TZX4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZYQ7", "url": "https://www.orthodb.org/?gene=A0A8V0ZYQ7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A3W4", "url": "https://www.orthodb.org/?gene=A0A8V1A3W4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A3W8", "url": "https://www.orthodb.org/?gene=A0A8V1A3W8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A692", "url": "https://www.orthodb.org/?gene=A0A8V1A692", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A8T7", "url": "https://www.orthodb.org/?gene=A0A8V1A8T7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ABA9", "url": "https://www.orthodb.org/?gene=A0A8V1ABA9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR44699", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44699", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR44699:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44699:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07686", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07686", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13927", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13927", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A140T8H1", "url": "https://www.uniprot.org/uniprotkb/A0A140T8H1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A140T8H1-1", "url": "https://www.uniprot.org/uniprotkb/A0A140T8H1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2TZX4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TZX4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2TZX4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TZX4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZYQ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYQ7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZYQ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYQ7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A3W4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3W4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A3W4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3W4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A3W8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3W8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A3W8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3W8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A692", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A692", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A692-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A692-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A8T7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8T7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A8T7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8T7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ABA9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABA9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ABA9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABA9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQNHIFATPNFGMFKYVMFGSVFLLGAFLGIVADVYVPLCAATCVLGHEYWCGRTLSQRSLHRWTSMVCPLEVSVSSGSIQVARGQTAVLPCTFTTNAALTNLNVIWMVTPLSNANQPEQVILYQGGQIFGGAPQFYGRVGFAVTMPTTSASIFINNTQLSDTGTYQCLVNNLPDRGSRNIGVIGLTVLVPPSAPLCRIQGSLEVGSDITLTCSSEEGIPRPTYLWEKLDNVPKLPPTATQDQVQGTVTLRNISTVSSGLYQCVASNAIGTSTCLLDLQVIAPHPWSIGLIAGAVATGAVVLIVCVVLVAIALFYWKNKHKEEEEEEIPNEIREDDLPPKCSSTTKTFHADASSSENDTLTSSNTYNSRYWNDPKANHATDSFTRFSNSNDARQPPFSRSGSTSARPVYANGGHPSPAAPKTLVVTASTAPSPQEVARSNGSVSRKPRLPHTRSYAVSQATLERIGAVPVMVPAQSRAGSLV", "length": 482, "header": "tr|A0A8V1A8T7-1|A0A8V1A8T7_CHICK Isoform 1 of Immunoglobulin superfamily member 11 OS=Gallus gallus OX=9031 GN=IGSF11 PE=4 SV=1 CANONICAL=A0A8V1A8T7-1" }, "isoforms": [ { "isoform_ac": "A0A140T8H1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8T7/entry#A0A140T8H1-1", "sequence": { "sequence": "MTLRRRPGGGGGRWVPAALAALLALRGMVCPLEVSVSSGSIQVARGQTAVLPCTFTTNAALTNLNVIWMVTPLSNANQPEQVILYQGGQIFGGAPQFYGRVGFAVTMPTTSASIFINNTQLSDTGTYQCLVNNLPDRGSRNIGVIGLTVLVPPSAPLCRIQGSLEVGSDITLTCSSEEGIPRPTYLWEKLDNVPKLPPTATQDQVQGTVTLRNISTVSSGLYQCVASNAIGTSTCLLDLQVIAPHPWSIGLIAGAVATGAVVLIVCVVLVAIALFYWKNKHKEEEEEEIPNEIREDDLPPKCSSTTKTFHADASSSENDTLTSSNTYNSRYWNDPKANHATDSFTRFSNSNDARQPPFSRSGSTSARPVYANGGHPSPAAPKTLVVTASTAPSPQEVARSNGSVSRKPRLPHTRSYAVSQATLERIGAVPVMVPAQSRAGSLV", "length": 443, "header": "tr|A0A140T8H1-1|A0A140T8H1_CHICK Computationally mapped isoform of Immunoglobulin superfamily member 11 OS=Gallus gallus OX=9031 GN=IGSF11 PE=4 SV=1 CANONICAL=A0A8V1A8T7-1" }, "locus": { "chromosome": "1", "start_pos": 80982532, "end_pos": 80896651, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010062636.1", "url": "https://www.ensembl.org/id/ENSGALT00010062636.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038726.1", "url": "https://www.ensembl.org/id/ENSGALP00010038726.1" } ] } }, { "isoform_ac": "A0A3Q2TZX4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8T7/entry#A0A3Q2TZX4-1", "sequence": { "sequence": "MACNGLSPQLRKPGSPVEGYAVSSWLSRGMVCPLEVSVSSGSIQVARGQTAVLPCTFTTNAALTNLNVIWMVTPLSNANQPEQVILYQGGQIFGGAPQFYGRVGFAVTMPTTSASIFINNTQLSDTGTYQCLVNNLPDRGSRNIGVIGLTVLVPPSAPLCRIQGSLEVGSDITLTCSSEEGIPRPTYLWEKLDNVPKLPPTATQDQVQGTVTLRNISTVSSGLYQCVASNAIGTSTCLLDLQVIAPHPWSIGLIAGAVATGAVVLIVCVVLVAIALFYWKNKHKEEEEEEIPNEIREDDLPPKCSSTTKTFHADASSSENDTLTSSNTYNSRYWNDPKANHATDSFTRFSNSNDARQPPFSRSGSTSARPVYANGGHPSPAAPKTLVVTASTAPSPQEVARSNGSVSRKPRLPHTRSYAVSQATLERIGAVPVMVPAQSRAGSLV", "length": 445, "header": "tr|A0A3Q2TZX4-1|A0A3Q2TZX4_CHICK Computationally mapped isoform of Immunoglobulin superfamily member 11 OS=Gallus gallus OX=9031 GN=IGSF11 PE=4 SV=1 CANONICAL=A0A8V1A8T7-1" }, "locus": { "chromosome": "1", "start_pos": 80982532, "end_pos": 80934538, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010062648.1", "url": "https://www.ensembl.org/id/ENSGALT00010062648.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038736.1", "url": "https://www.ensembl.org/id/ENSGALP00010038736.1" } ] } }, { "isoform_ac": "A0A8V0ZYQ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8T7/entry#A0A8V0ZYQ7-1", "sequence": { "sequence": "MVCPLEVSVSSGSIQVARGQTAVLPCTFTTNAALTNLNVIWMVTPLSNANQPEQVILYQGGQIFGGAPQFYGRVGFAVTMPTTSASIFINNTQLSDTGTYQCLVNNLPDRGSRNIGVIGLTVLVPPSAPLCRIQGSLEVGSDITLTCSSEEGIPRPTYLWEKLDNVPKLPPTATQDQVQGTVTLRNISTVSSGLYQCVASNAIGTSTCLLDLQVIAPHPWSIGLIAGAVATGAVVLIVCVVLVAIALFYWKNKHKEEEEEEIPNEIREDDLPPKCSSTTKTFHADASSSENDTLTSSNTYNSRYWNDPKANHATDSFTRFSNSNDARQPPFSRSGSTSARPVYANGGHPSPAAPKTLVVTASTAPSPQEVARSNGSVSRKPRLPHTRSYAVSQATLERIGAVPVMVPAQSRAGSLV", "length": 416, "header": "tr|A0A8V0ZYQ7-1|A0A8V1A8T7_CHICK Computationally mapped isoform of Immunoglobulin superfamily member 11 OS=Gallus gallus OX=9031 GN=IGSF11 PE=4 SV=1 CANONICAL=A0A8V1A8T7-1" }, "locus": { "chromosome": "1", "start_pos": 80982532, "end_pos": 80977769, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010062620.1", "url": "https://www.ensembl.org/id/ENSGALT00010062620.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038715.1", "url": "https://www.ensembl.org/id/ENSGALP00010038715.1" } ] } }, { "isoform_ac": "A0A8V1A3W4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8T7/entry#A0A8V1A3W4-1", "sequence": { "sequence": "MQFGMVCPLEVSVSSGSIQVARGQTAVLPCTFTTNAALTNLNVIWMVTPLSNANQPEQVILYQGGQIFGGAPQFYGRVGFAVTMPTTSASIFINNTQLSDTGTYQCLVNNLPDRGSRNIGVIGLTVLVPPSAPLCRIQGSLEVGSDITLTCSSEEGIPRPTYLWEKLDNVPKLPPTATQDQVQGTVTLRNISTVSSGLYQCVASNAIGTSTCLLDLQVIAPHPWSIGLIAGAVATGAVVLIVCVVLVAIALFYWKNKHKEEEEEEIPNEIREDDLPPKCSSTTKTFHADASSSENDTLTSSNTYNSRYWNDPKANHATDSFTRFSNSNDARQPPFSRSGSTSARPVYANGGHPSPAAPKTLVVTASTAPSPQEVARSNGSVSRKPRLPHTRSYAVSQATLERIGAVPVMVPAQSRAGSLV", "length": 420, "header": "tr|A0A8V1A3W4-1|A0A8V1A8T7_CHICK Computationally mapped isoform of Immunoglobulin superfamily member 11 OS=Gallus gallus OX=9031 GN=IGSF11 PE=4 SV=1 CANONICAL=A0A8V1A8T7-1" }, "locus": { "chromosome": "1", "start_pos": 80982532, "end_pos": 80910575, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010062623.1", "url": "https://www.ensembl.org/id/ENSGALT00010062623.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038717.1", "url": "https://www.ensembl.org/id/ENSGALP00010038717.1" } ] } }, { "isoform_ac": "A0A8V1A3W8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8T7/entry#A0A8V1A3W8-1", "sequence": { "sequence": "MKIWGMVCPLEVSVSSGSIQVARGQTAVLPCTFTTNAALTNLNVIWMVTPLSNANQPEQVILYQGGQIFGGAPQFYGRVGFAVTMPTTSASIFINNTQLSDTGTYQCLVNNLPDRGSRNIGVIGLTVLVPPSAPLCRIQGSLEVGSDITLTCSSEEGIPRPTYLWEKLDNVPKLPPTATQDQVQGTVTLRNISTVSSGLYQCVASNAIGTSTCLLDLQVIAPHPWSIGLIAGAVATGAVVLIVCVVLVAIALFYWKNKHKEEEEEEIPNEIREDDLPPKCSSTTKTFHADASSSENDTLTSSNTYNSRYWNDPKANHATDSFTRFSNSNDARQPPFSRSGSTSARPVYANGGHPSPAAPKTLVVTASTAPSPQEVARSNGSVSRKPRLPHTRSYAVSQATLERIGAVPVMVPAQSRAGSLV", "length": 421, "header": "tr|A0A8V1A3W8-1|A0A8V1A8T7_CHICK Computationally mapped isoform of Immunoglobulin superfamily member 11 OS=Gallus gallus OX=9031 GN=IGSF11 PE=4 SV=1 CANONICAL=A0A8V1A8T7-1" }, "locus": { "chromosome": "1", "start_pos": 80982532, "end_pos": 80918840, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010062631.1", "url": "https://www.ensembl.org/id/ENSGALT00010062631.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038722.1", "url": "https://www.ensembl.org/id/ENSGALP00010038722.1" } ] } }, { "isoform_ac": "A0A8V1A692-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8T7/entry#A0A8V1A692-1", "sequence": { "sequence": "MSSLMVILMDKHSGMVCPLEVSVSSGSIQVARGQTAVLPCTFTTNAALTNLNVIWMVTPLSNANQPEQVILYQGGQIFGGAPQFYGRVGFAVTMPTTSASIFINNTQLSDTGTYQCLVNNLPDRGSRNIGVIGLTVLVPPSAPLCRIQGSLEVGSDITLTCSSEEGIPRPTYLWEKLDNVPKLPPTATQDQVQGTVTLRNISTVSSGLYQCVASNAIGTSTCLLDLQVIAPHPWSIGLIAGAVATGAVVLIVCVVLVAIALFYWKNKHKEEEEEEIPNEIREDDLPPKCSSTTKTFHADASSSENDTLTSSNTYNSRYWNDPKANHATDSFTRFSNSNDARQPPFSRSGSTSARPVYANGGHPSPAAPKTLVVTASTAPSPQEVARSNGSVSRKPRLPHTRSYAVSQATLERIGAVPVMVPAQSRAGSLV", "length": 430, "header": "tr|A0A8V1A692-1|A0A8V1A8T7_CHICK Computationally mapped isoform of Immunoglobulin superfamily member 11 OS=Gallus gallus OX=9031 GN=IGSF11 PE=4 SV=1 CANONICAL=A0A8V1A8T7-1" }, "locus": { "chromosome": "1", "start_pos": 80982532, "end_pos": 80940577, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010062626.1", "url": "https://www.ensembl.org/id/ENSGALT00010062626.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038719.1", "url": "https://www.ensembl.org/id/ENSGALP00010038719.1" } ] } }, { "isoform_ac": "A0A8V1A8T7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8T7/entry#A0A8V1A8T7-1", "sequence": { "sequence": "MQNHIFATPNFGMFKYVMFGSVFLLGAFLGIVADVYVPLCAATCVLGHEYWCGRTLSQRSLHRWTSMVCPLEVSVSSGSIQVARGQTAVLPCTFTTNAALTNLNVIWMVTPLSNANQPEQVILYQGGQIFGGAPQFYGRVGFAVTMPTTSASIFINNTQLSDTGTYQCLVNNLPDRGSRNIGVIGLTVLVPPSAPLCRIQGSLEVGSDITLTCSSEEGIPRPTYLWEKLDNVPKLPPTATQDQVQGTVTLRNISTVSSGLYQCVASNAIGTSTCLLDLQVIAPHPWSIGLIAGAVATGAVVLIVCVVLVAIALFYWKNKHKEEEEEEIPNEIREDDLPPKCSSTTKTFHADASSSENDTLTSSNTYNSRYWNDPKANHATDSFTRFSNSNDARQPPFSRSGSTSARPVYANGGHPSPAAPKTLVVTASTAPSPQEVARSNGSVSRKPRLPHTRSYAVSQATLERIGAVPVMVPAQSRAGSLV", "length": 482, "header": "tr|A0A8V1A8T7-1|A0A8V1A8T7_CHICK Isoform 1 of Immunoglobulin superfamily member 11 OS=Gallus gallus OX=9031 GN=IGSF11 PE=4 SV=1 CANONICAL=A0A8V1A8T7-1" }, "locus": { "chromosome": "1", "start_pos": 80982532, "end_pos": 80974578, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010062618.1", "url": "https://www.ensembl.org/id/ENSGALT00010062618.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038713.1", "url": "https://www.ensembl.org/id/ENSGALP00010038713.1" } ] } }, { "isoform_ac": "A0A8V1ABA9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8T7/entry#A0A8V1ABA9-1", "sequence": { "sequence": "MCVRDLSAFSQPGMVCPLEVSVSSGSIQVARGQTAVLPCTFTTNAALTNLNVIWMVTPLSNANQPEQVILYQGGQIFGGAPQFYGRVGFAVTMPTTSASIFINNTQLSDTGTYQCLVNNLPDRGSRNIGVIGLTVLVPPSAPLCRIQGSLEVGSDITLTCSSEEGIPRPTYLWEKLDNVPKLPPTATQDQVQGTVTLRNISTVSSGLYQCVASNAIGTSTCLLDLQVIAPHPWSIGLIAGAVATGAVVLIVCVVLVAIALFYWKNKHKEEEEEEIPNEIREDDLPPKCSSTTKTFHADASSSENDTLTSSNTYNSRYWNDPKANHATDSFTRFSNSNDARQPPFSRSGSTSARPVYANGGHPSPAAPKTLVVTASTAPSPQEVARSNGSVSRKPRLPHTRSYAVSQATLERIGAVPVMVPAQSRAGSLV", "length": 429, "header": "tr|A0A8V1ABA9-1|A0A8V1ABA9_CHICK Computationally mapped isoform of Immunoglobulin superfamily member 11 OS=Gallus gallus OX=9031 GN=IGSF11 PE=4 SV=1 CANONICAL=A0A8V1A8T7-1" }, "locus": { "chromosome": "1", "start_pos": 80982532, "end_pos": 80976714, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010062616.1", "url": "https://www.ensembl.org/id/ENSGALT00010062616.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038711.1", "url": "https://www.ensembl.org/id/ENSGALP00010038711.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:418346", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418346", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1MND5-1", "protein_name": "Immunoglobulin superfamily member 11", "gene_name": "IGSF11", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSLVGLLLLWDCFCSTGVAASLEVSESPGSVQVARGQTAVLPCTFTTSAALINLNVIWMVIPLSNANQPEQVILYQGGQMFDGAPRFHGRVGFTGTMPATNVSIFINNTQLSDTGTYQCLVNNLPDRGGRNIGVTGLTVLVPPSAPHCQIQGSQDIGSDVILLCSSEEGIPRPTYLWEKLDNTLKLPPTATQDQVQGTVTIRNISALSSGLYQCVASNAIGTSTCLLDLQVISPQPRSIGLIAGAIGTGAVIIIFCIALILGAFFYWRSKNKEEEEEEIPNEIREDDLPPKCSSSAKAFHMEISSSENNTLTSSNTYNSRYWSSNPKAHRNTESFGHFGDLRQSFSLHSGNASVPAIYANGSHLAPAPHKTLVVTANRGSSPPAVSRSNGSVSRKARPPPVPSLHTHSYTVSQATLERIGAVPVMVPAQSRAGSLV", "length": 436 }, "evidence": [ { "id": "A0A8V1A8T7", "url": "https://omabrowser.org/oma/group/A0A8V1A8T7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P0C673-1", "protein_name": "Immunoglobulin superfamily member 11", "gene_name": "Igsf11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTRRRSAPASWLLVSLLGVATSLEVSESPGSVQVARGQTAVLPCAFSTSAALLNLNVIWMVIPLSNANQPEQVILYQGGQMFDGALRFHGRVGFTGTMPATNVSIFINNTQLSDTGTYQCLVNNLPDRGGRNIGVTGLTVLVPPSAPQCQIQGSQDLGSDVILLCSSEEGIPRPTYLWEKLDNTLKLPPTATQDQVQGTVTIRNISALSSGLYQCVASNAIGTSTCLLDLQVISPQPRSVGVIAGAVGTGAVLIVICLALISGAFFYWRSKNKEEEEEEIPNEIREDDLPPKCSSAKAFHTEISSSENNTLTSSNTYNSRYWNNNPKPHRNTESFNHFSDLRQSFSGNAVIPSIYANGNHLVLGPHKTLVVTANRGSSPQVLPRNNGSVSRKPWPQHTHSYTVSQMTLERIGAVPVMVPAQSRAGSLV", "length": 428 }, "evidence": [ { "id": "A0A8V1A8T7", "url": "https://omabrowser.org/oma/group/A0A8V1A8T7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5DX21-1", "protein_name": "Immunoglobulin superfamily member 11", "gene_name": "IGSF11", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTSQRSPLAPLLLLSLHGVAASLEVSESPGSIQVARGQPAVLPCTFTTSAALINLNVIWMVTPLSNANQPEQVILYQGGQMFDGAPRFHGRVGFTGTMPATNVSIFINNTQLSDTGTYQCLVNNLPDIGGRNIGVTGLTVLVPPSAPHCQIQGSQDIGSDVILLCSSEEGIPRPTYLWEKLDNTLKLPPTATQDQVQGTVTIRNISALSSGLYQCVASNAIGTSTCLLDLQVISPQPRNIGLIAGAIGTGAVIIIFCIALILGAFFYWRSKNKEEEEEEIPNEIREDDLPPKCSSAKAFHTEISSSDNNTLTSSNAYNSRYWSNNPKVHRNTESVSHFSDLGQSFSFHSGNANIPSIYANGTHLVPGQHKTLVVTANRGSSPQVMSRSNGSVSRKPRPPHTHSYTISHATLERIGAVPVMVPAQSRAGSLV", "length": 431 }, "evidence": [ { "id": "A0A8V1A8T7", "url": "https://omabrowser.org/oma/group/A0A8V1A8T7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5U2P2-1", "protein_name": "Immunoglobulin superfamily member 11", "gene_name": "Igsf11", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTRRRSALASWLLLSLLGVAASLEVSESPGSVQVARGQTAVLPCAFSTSAALLNLNVIWMVIPLSNANQPEQVILYQGGQMFDGALRFHGRVGFTGTMPATNVSIFINNTQLSDTGTYQCLVNNLPDRGGRNIGVTGLTVLVPPSAPNCQIQGSQDIGSDVILLCSSEEGIPRPTYLWEKLDNTLKLPPTATQDQVQGTVTIRNISALSSGLYQCVASNAIGTSTCLLDLQVISPQPRSVGVIAGAVGTGAVLIVICLALTSGAFFYWRSKNKEEEEEEIPNEIREDDLPPKCSSAKAFHTEISSSENNTLTSSNTYNSRYWNNNPKPHKNTESFNHFSDLRQSFSGNAVIPSIYANGNHLVLGPHKTLVVTANRGSSPQVMPRNNGSVSRKPWSQHTHSYTVSQMTLERIGAVPVMVPAQSRAGSLV", "length": 428 }, "evidence": [ { "id": "A0A8V1A8T7", "url": "https://omabrowser.org/oma/group/A0A8V1A8T7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A8T7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8T7" } ], "pmid": "" }, { "name": "cell-cell junction", "id": "GO:0005911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005911", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A8T7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8T7" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A8T7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8T7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "positive regulation of long-term synaptic potentiation", "id": "GO:1900273", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900273", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A8T7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8T7" } ], "pmid": "" }, { "name": "homophilic cell adhesion via plasma membrane adhesion molecules", "id": "GO:0007156", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007156", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A8T7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8T7" } ], "pmid": "" }, { "name": "regulation of presynapse assembly", "id": "GO:1905606", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905606", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A8T7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8T7" } ], "pmid": "" }, { "name": "trans-synaptic signaling", "id": "GO:0099537", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099537", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A8T7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8T7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "ionotropic glutamate receptor binding", "id": "GO:0035255", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035255", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A8T7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8T7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 156, "end_pos": 158, "annotation": "n_glycosylation_sequon" }, { "start_pos": 252, "end_pos": 254, "annotation": "n_glycosylation_sequon" }, { "start_pos": 357, "end_pos": 359, "annotation": "n_glycosylation_sequon" }, { "start_pos": 440, "end_pos": 442, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1A8T7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8T7" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 70, "end_pos": 172, "start_aa": "Pro", "end_aa": "Asn", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 156, "end_pos": 158 }, { "start_pos": 252, "end_pos": 254 }, { "start_pos": 357, "end_pos": 359 }, { "start_pos": 440, "end_pos": 442 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A8V7-1", "uniprot_ac": "A0A8V1A8V7", "uniprot_id": "A0A8V1A8V7_CHICK", "mass": { "chemical_mass": 128391.0, "monoisotopic_mass": 128391.0 }, "refseq": {}, "gene_names": [ { "name": "COBLL1", "type": "recommended", "evidence": [ { "id": "A0A8V1A8V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8V7" } ] } ], "protein_names": [ { "name": "Cordon-bleu WH2 repeat protein like 1", "type": "synonym", "evidence": [ { "id": "A0A8V1A8V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8V7/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A8V7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8V7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "COBLL1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8V7", "locus": { "chromosome": "7", "start_pos": 19741759, "end_pos": 19667567, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010025659", "url": "https://www.ensembl.org/id/ENSGALG00010025659" } ] } } ], "crossref": [ { "id": "A0A8V1A8V7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A8V7", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd21801", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21801", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "424182", "url": "https://www.ncbi.nlm.nih.gov/gene/424182", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019025", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019025", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039895", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039895", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ETTENRC", "url": "https://omabrowser.org/oma/group/ETTENRC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZYR5", "url": "https://www.orthodb.org/?gene=A0A8V0ZYR5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A6A5", "url": "https://www.orthodb.org/?gene=A0A8V1A6A5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A8U4", "url": "https://www.orthodb.org/?gene=A0A8V1A8U4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A8V7", "url": "https://www.orthodb.org/?gene=A0A8V1A8V7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21557", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21557", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21557:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21557:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF09469", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09469", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZYR5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYR5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZYR5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYR5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A6A5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6A5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A6A5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6A5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A8U4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8U4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A8U4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8U4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A8V7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8V7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A8V7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8V7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPALGGEAERGRLPQPTPRRRKAKAPPPPSETKTVTDCPFDDTESATIIMEQKENVIDKDIELSVVLPGDVIKYTTVNGRKPMMDLLIFLCAQYHLNPSSYTIELISAENCQIKFKPNTPVGMLEVEKVIVKPKQMDKKKPVPVIPEQTVRVVINYKKTQKTVVRVSPYSPLQELIPIICSKCEFDPSHTVLLKNYQSQEALDVTKSLNDLGLRELYAMDISRATSPVDLNLPSLKDSCRVSENSDVLKEKENKGFFSFFQRSKKKREQTASAPATPLMSKPRPMFTTRSGTGSKQYDSNTLPSEMPKKRRAPLPPMPNSQSAPQELAEVKTESDTVKSNSLDRNEQTPLGLVRKGSLPLSDTASVNSLRRMKRKAPSPPSRTPEDRSESSNETVTESTQSIPTEVEGRAAQMQSETGARTSEYSLEEIDEKEEMSVQEGEESGSTGTSLRTGEATAAFSSMEVPLETERNDCASSVPVPGTVSVDNSQSFKEEKQENMSTDGKELQTQISSDQAAFEKDRKLRILEENKNYDHSDRTLLPTNEEGGEEQTAKIKAVDFRENSKLEVDRLSNCQASKNDIAISHKNYSQLIPGKQDEKTSQTSLDTVKTHDVAIQTGPLVSNLGRTAQKEMIVPQEYESSTFKGMVHQHSTDTNNPGLRVMQGVHKDEEISTERNLQRQEVSYEKTIPMKDEIHICTNSSNVTSPETIAKTPDGSPIRSYPLYRQDMKPKPKPANEITRDYIPKIGMTTYKIVPPPKSLETMKSWESEVSDCKDQEVSASKNSLKYEDPKEFIMQTETPHLPKSTGHLQTGLQNIPAAKNDQLHRVNSISEHGVPSGARVSTEVKQIETVSSKQHVPLMLSLSDSNAASETREKSNTLSPTTKPSSFYLQMQRRVSGHYVSSAIARSTICAPNSIQNEVKNTEMEKKISSPDETSLHATNSFSPPVDEDKDDDGKKIESSTSPVKNNKPPSFPSCQPAPLNLRTLRTFAVPKPYSSSRPSPFALAVSSAVKRSQSFNKTRTISSLAPREEFPVELSSVSSAAEFSSATSMPQVKNLSLHGITGGPQNSLMDKKSSNVSNSEQKIEAQSGASADHPRPVIMRQTSTPVQRSDPEQIHQSLLAAIRSGEAAARLKRVGPPSNTVSVNGRARLNYLYSTEAKANH", "length": 1162, "header": "tr|A0A8V1A8V7-1|A0A8V1A8V7_CHICK Isoform 1 of Cordon-bleu WH2 repeat protein like 1 OS=Gallus gallus OX=9031 GN=COBLL1 PE=1 SV=1 CANONICAL=A0A8V1A8V7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZYR5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8V7/entry#A0A8V0ZYR5-1", "sequence": { "sequence": "MGLGPLAHGVLVRRVRVNRVFRRKAKAPPPPSETKTVTDCPFDDTESATIIMEQKENVIDKDIELSVVLPGDVIKYTTVNGRKPMMDLLIFLCAQYHLNPSSYTIELISAENCQIKFKPNTPVGMLEVEKVIVKPKQMDKKKPVPVIPEQTVRVVINYKKTQKTVVRVSPYSPLQELIPIICSKCEFDPSHTVLLKNYQSQEALDVTKSLNDLGLRELYAMDISRATSPVDLNLPSLKDSCRVSENSDVLKEKENKGFFSFFQRSKKKREQTASAPATPLMSKPRPMFTTRSGTGSKQYDSNTLPSEMPKKRRAPLPPMPNSQSAPQELAEVKTESDTVKSNSLDRNEQTPLGLVRKGSLPLSDTASVNSLRRMKRKAPSPPSRTPEDRSESSNETVTESTQSIPTEVEGRAAQMQSETGARTSEYSLEEIDEKEEMSVQEGEESGSTGTSLRTGEATAAFSSMEVPLETERNDCASSVPVPGTVSVDNSQSFKEEKQENMSTDGKELQTQISSDQAAFEKDRKLRILEENKNYDHSDRTLLPTNEEGGEEQTAKIKAVDFRENSKLEVDRLSNCQASKNDIAISHKNYSQLIPGKQDEKTSQTSLDTVKTHDVAIQTGPLVSNLGRTAQKEMIVPQEYESSTFKGMVHQHSTDTNNPGLRVMQGVHKDEEISTERNLQRQEVSYEKTIPMKDEIHICTNSSNVTSPETIAKTPDGSPIRSYPLYRQDMKPKPKPANEITRDYIPKIGMTTYKIVPPPKSLETMKSWESEVSDCKDQEVSASKNSLKYEDPKEFIMQTETPHLPKSTGHLQTGLQNIPAAKNDQLHRVNSISEHGVPSGARVSTEVKQIETVSSKQHVPLMLSLSDSNAASETREKSNTLSPTTKPSSFYLQMQRRVSGHYVSSAIARSTICAPNSIQNEVKNTEMEKKISSPDETSLHATNSFSPPVDEDKDDDGKKIESSTSPVKNNKPPSFPSCQPAPLNLRTLRTFAVPKPYSSSRPSPFALAVSSAVKRSQSFNKTRTISSLAPREEFPVELSSVSSAAEFSSATSMPQVKNLSLHGITGGPQNSLMDKKSSNVSNSEQKIEAQSGASADHPRPVIMRQTSTPVQRSDPEQIHQSLLAAIRSGEAAARLKRVSFHHCIHNNELMVLPSKLPY", "length": 1157, "header": "tr|A0A8V0ZYR5-1|A0A8V1A8V7_CHICK Computationally mapped isoform of Cordon-bleu WH2 repeat protein like 1 OS=Gallus gallus OX=9031 GN=COBLL1 PE=1 SV=1 CANONICAL=A0A8V1A8V7-1" }, "locus": { "chromosome": "7", "start_pos": 19737793, "end_pos": 19678499, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010062635.1", "url": "https://www.ensembl.org/id/ENSGALT00010062635.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038725.1", "url": "https://www.ensembl.org/id/ENSGALP00010038725.1" } ] } }, { "isoform_ac": "A0A8V1A6A5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8V7/entry#A0A8V1A6A5-1", "sequence": { "sequence": "MHTARRSRCGHAVLRKAKAPPPPSETKTVTDCPFDDTESATIIMEQKENVIDKDIELSVVLPGDVIKYTTVNGRKPMMDLLIFLCAQYHLNPSSYTIELISAENCQIKFKPNTPVGMLEVEKVIVKPKQMDKKKPVPVIPEQTVRVVINYKKTQKTVVRVSPYSPLQELIPIICSKCEFDPSHTVLLKNYQSQEALDVTKSLNDLGLRELYAMDISRATSPVDLNLPSLKDSCRVSENSDVLKEKENKGFFSFFQRSKKKREQTASAPATPLMSKPRPMFTTRSGTGSKQYDSNTLPSEMPKKRRAPLPPMPNSQSAPQELAEVKTESDTVKSNSLDRNEQTPLGLVRKGSLPLSDTASVNSLRRMKRKAPSPPSRTPEDRSESSNETVTESTQSIPTEVEGRAAQMQSETGARTSEYSLEEIDEKEEMSVQEGEESGSTGTSLRTGEATAAFSSMEVPLETERNDCASSVPVPGTVSVDNSQSFKEEKQENMSTDGKELQTQISSDQAAFEKDRKLRILEENKNYDHSDRTLLPTNEEGGEEQTAKIKAVDFRENSKLEVDRLSNCQASKNDIAISHKNYSQLIPGKQDEKTSQTSLDTVKTHDVAIQTGPLVSNLGRTAQKEMIVPQEYESSTFKGMVHQHSTDTNNPGLRVMQGVHKDEEISTERNLQRQEVSYEKTIPMKDEIHICTNSSNVTSPETIAKTPDGSPIRSYPLYRQDMKPKPKPANEITRDYIPKIGMTTYKIVPPPKSLETMKSWESEVSDCKDQEVSASKNSLKYEDPKEFIMQTETPHLPKSTGHLQTGLQNIPAAKNDQLHRVNSISEHGVPSGARVSTEVKQIETVSSKQHVPLMLSLSDSNAASETREKSNTLSPTTKPSSFYLQMQRRVSGHYVSSAIARSTICAPNSIQNEVKNTEMEKKISSPDETSLHATNSFSPPVDEDKDDDGKKIESSTSPVKNNKPPSFPSCQPAPLNLRTLRTFAVPKPYSSSRPSPFALAVSSAVKRSQSFNKTRTISSLAPREEFPVELSSVSSAAEFSSATSMPQVKNLSLHGITGGPQNSLMDKKSSNVSNSEQKIEAQSGASADHPRPVIMRQTSTPVQRSDPEQIHQSLLAAIRSGEAAARLKRVGPPSNTVSVNGRARLNYLYSTEAKANH", "length": 1156, "header": "tr|A0A8V1A6A5-1|A0A8V1A8V7_CHICK Computationally mapped isoform of Cordon-bleu WH2 repeat protein like 1 OS=Gallus gallus OX=9031 GN=COBLL1 PE=1 SV=1 CANONICAL=A0A8V1A8V7-1" }, "locus": { "chromosome": "7", "start_pos": 19740826, "end_pos": 19669728, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010062646.1", "url": "https://www.ensembl.org/id/ENSGALT00010062646.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038734.1", "url": "https://www.ensembl.org/id/ENSGALP00010038734.1" } ] } }, { "isoform_ac": "A0A8V1A8U4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8V7/entry#A0A8V1A8U4-1", "sequence": { "sequence": "MEQKENVIDKDIELSVVLPGDVIKYTTVNGRKPMMDLLIFLCAQYHLNPSSYTIELISAENCQIKFKPNTPVGMLEVEKVIVKPKQMDKKKPVPVIPEQTVRVVINYKKTQKTVVRVSPYSPLQELIPIICSKCEFDPSHTVLLKNYQSQEALDVTKSLNDLGLRELYAMDISRATSPVDLNLPSLKDSCRVSENSDVLKEKENKGFFSFFQRSKKKREQTASAPATPLMSKPRPMFTTRSGTGSKQYDSNTLPSEMPKKRRAPLPPMPNSQSAPQELAEVKTESDTVKSNSLDRNEQTPLGLVRKGSLPLSDTASVNSLRRMKRKAPSPPSRTPEDRSESSNETVTESTQSIPTEVEGRAAQMQSETGARTSEYSLEEIDEKEEMSVQEGEESGSTGTSLRTGEATAAFSSMEVPLETERNDCASSVPVPGTVSVDNSQSFKEEKQENMSTDGKELQTQISSDQAAFEKDRKLRILEENKNYDHSDRTLLPTNEEGGEEQTAKIKAVDFRENSKLEVDRLSNCQASKNDIAISHKNYSQLIPGKQDEKTSQTSLDTVKTHDVAIQTGPLVSNLGRTAQKEMIVPQEYESSTFKGMVHQHSTDTNNPGLRVMQGVHKDEEISTERNLQRQEVSYEKTIPMKDEIHICTNSSNVTSPETIAKTPDGSPIRSYPLYRQDMKPKPKPANEITRDYIPKIGMTTYKIVPPPKSLETMKSWESEVSDCKDQEVSASKNSLKYEDPKEFIMQTETPHLPKSTGHLQTGLQNIPAAKNDQLHRVNSISEHGVPSGARVSTEVKQIETVSSKQHVPLMLSLSDSNAASETREKSNTLSPTTKPSSFYLQMQRRVSGHYVSSAIARSTICAPNSIQNEVKNTEMEKKISSPDETSLHATNSFSPPVDEDKDDDGKKIESSTSPVKNNKPPSFPSCQPAPLNLRTLRTFAVPKPYSSSRPSPFALAVSSAVKRSQSFNKTRTISSLAPREEFPVELSSVSSAAEFSSATSMPQVKNLSLHGITGGPQNSLMDKKSSNVSNSEQKIEAQSGASADHPRPVIMRQTSTPVQRSDPEQIHQSLLAAIRSGEAAARLKRVGPPSNTVSVNGRARLNYLYSTEAKANH", "length": 1113, "header": "tr|A0A8V1A8U4-1|A0A8V1A8U4_CHICK Computationally mapped isoform of Cordon-bleu WH2 repeat protein like 1 OS=Gallus gallus OX=9031 GN=COBLL1 PE=1 SV=1 CANONICAL=A0A8V1A8V7-1" }, "locus": { "chromosome": "7", "start_pos": 19740826, "end_pos": 19709499, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010062632.1", "url": "https://www.ensembl.org/id/ENSGALT00010062632.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038723.1", "url": "https://www.ensembl.org/id/ENSGALP00010038723.1" } ] } }, { "isoform_ac": "A0A8V1A8V7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8V7/entry#A0A8V1A8V7-1", "sequence": { "sequence": "MPALGGEAERGRLPQPTPRRRKAKAPPPPSETKTVTDCPFDDTESATIIMEQKENVIDKDIELSVVLPGDVIKYTTVNGRKPMMDLLIFLCAQYHLNPSSYTIELISAENCQIKFKPNTPVGMLEVEKVIVKPKQMDKKKPVPVIPEQTVRVVINYKKTQKTVVRVSPYSPLQELIPIICSKCEFDPSHTVLLKNYQSQEALDVTKSLNDLGLRELYAMDISRATSPVDLNLPSLKDSCRVSENSDVLKEKENKGFFSFFQRSKKKREQTASAPATPLMSKPRPMFTTRSGTGSKQYDSNTLPSEMPKKRRAPLPPMPNSQSAPQELAEVKTESDTVKSNSLDRNEQTPLGLVRKGSLPLSDTASVNSLRRMKRKAPSPPSRTPEDRSESSNETVTESTQSIPTEVEGRAAQMQSETGARTSEYSLEEIDEKEEMSVQEGEESGSTGTSLRTGEATAAFSSMEVPLETERNDCASSVPVPGTVSVDNSQSFKEEKQENMSTDGKELQTQISSDQAAFEKDRKLRILEENKNYDHSDRTLLPTNEEGGEEQTAKIKAVDFRENSKLEVDRLSNCQASKNDIAISHKNYSQLIPGKQDEKTSQTSLDTVKTHDVAIQTGPLVSNLGRTAQKEMIVPQEYESSTFKGMVHQHSTDTNNPGLRVMQGVHKDEEISTERNLQRQEVSYEKTIPMKDEIHICTNSSNVTSPETIAKTPDGSPIRSYPLYRQDMKPKPKPANEITRDYIPKIGMTTYKIVPPPKSLETMKSWESEVSDCKDQEVSASKNSLKYEDPKEFIMQTETPHLPKSTGHLQTGLQNIPAAKNDQLHRVNSISEHGVPSGARVSTEVKQIETVSSKQHVPLMLSLSDSNAASETREKSNTLSPTTKPSSFYLQMQRRVSGHYVSSAIARSTICAPNSIQNEVKNTEMEKKISSPDETSLHATNSFSPPVDEDKDDDGKKIESSTSPVKNNKPPSFPSCQPAPLNLRTLRTFAVPKPYSSSRPSPFALAVSSAVKRSQSFNKTRTISSLAPREEFPVELSSVSSAAEFSSATSMPQVKNLSLHGITGGPQNSLMDKKSSNVSNSEQKIEAQSGASADHPRPVIMRQTSTPVQRSDPEQIHQSLLAAIRSGEAAARLKRVGPPSNTVSVNGRARLNYLYSTEAKANH", "length": 1162, "header": "tr|A0A8V1A8V7-1|A0A8V1A8V7_CHICK Isoform 1 of Cordon-bleu WH2 repeat protein like 1 OS=Gallus gallus OX=9031 GN=COBLL1 PE=1 SV=1 CANONICAL=A0A8V1A8V7-1" }, "locus": { "chromosome": "7", "start_pos": 19740826, "end_pos": 19667849, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010062653.1", "url": "https://www.ensembl.org/id/ENSGALT00010062653.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038738.1", "url": "https://www.ensembl.org/id/ENSGALP00010038738.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 17, "start_aa": "Thr", "end_pos": 17, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr17", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A287A580-1", "protein_name": "Cordon-bleu WH2 repeat protein like 1", "gene_name": "COBLL1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGQAVTRRLGARARAAPSRAMDGGVPSAQDALAAPQPAAPAGRKPKAKAPLPPAETKYLDASSVDDSVESSAFIMEQKENMIDKDIELLVVLPGDIIKYTTVHGSKPMMDLLIFLCAKYHLNPSSHTIDLLSAEKNPIKFKPNTPIGMLEVEKVILKPKILDKKKPTPIIPEKTVRVVINFKKTQKTIVRVSPHAPLQELAPIICSKCEFDPLHTLLLKDYQSQEPLDLTKSLNDLGLRELYAMDVSRATSVTAFNKSSLQESCQISQNLDIMKDKENKGFFSFFQRSKKKREQTASAPATPLVSKHRPTFPKYNTVSKQYISNTLPSDAPKKRRAPLPPMPGSQSAPQDLAHIQERPASCVVKSTSLDETDENSCGAGIVRTGSLQLSSRSTGNSSLKRTKRKAPSPPSKIALQQSDENSHVTALQSVPAVPPDSVLEANSSEGLSSPEVSLGPGLPRPEQGTVPELLAGAPLSERPATPEAAAASLPSGISSDYSLEEIDEKEELSEVPRDEAENTSLKSQDIPIGSSDIINTLKNDPDSALGSSTGKSSQNSKEEKQESRNTDGQGPHIMVYNASNEESIVDGVRNLMSLDPSQEKDQNEIIVIPTNTENNMENGVRTEINVGGIAKNNNVDMQVDRLPNYQAYKTDTARSYKENHLATSSAPDQKMSEPSTEKTKMQDAAIQTIPSCDSFDGNHQDHNLSDVKVDESVQTSGNNKSIQHSSLSPQDPIDTSGEFRSQAPLPTVYSEELLPRKDPICAHGNDDLLSPVDGTDKNSTASYIKNSPLYRQDYSPKPKPSNEITREYIPKIGMTTYKIVPPRSLEISKDWELETTGYKNDQEIKILGKKDTQENVKETAIQTEDLVISESLKEPREDLKPEPTLRTEHQVQREESCTRGTIVNPLKPTPRMTRDTGTAPFAPSLEDINNVLESKLKSRVSNPQTKPSSFFLQMQKRVSGHYVTSAAAKSVQAAPNPTPKELIKKEVESDTVPPPEPTLSPLSKSPPQPHIKNTDDDSIKKPTETSPPPLASPPPVAPKPVPLPTSQSAALNLKTLKTFGAPRPYSSSAPSPFALAVVKRSQSFSKGRTGLCNEEVDSASSPTPTDTQEGKIPSVNTFVDIPQLSVSRKENNSVHNEQNLQIPSPTDCPSFTLKRQSSSTFQSSDPEQIRQSLLTAIRSGEAAAKLKRVTVPSNTVSVNGRSRLSHSMSLDAQDGH", "length": 1215 }, "evidence": [ { "id": "A0A8V1A8V7", "url": "https://omabrowser.org/oma/group/A0A8V1A8V7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0ABK0LX00-1", "protein_name": "Cordon-bleu WH2 repeat protein-like 1", "gene_name": "Cobll1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGTEYNCCKVSLASSACLLLRFLWSLTFAYCTVLYLGTNKPSPGEHIELSEGKLSVSTAGAKHTSFLHEVPNHRRKTKAKAPLPPAEMKGMDVSSAEDPVESIPVSTEQHDNMIDKDIELSVVLPGDVLKSTTVHGSKPMMDLLVFLCAQYHLNPSSHTINLLSAEENLIKFKPNTPIGMLEVEKVILKPKSLDKKKPTPIIPEKTVRVVINFKKTQKTIVRVSPHSPLQDLAPIICSKCEFDPLHTVLLKDYQAQEPLDLTKSLNDLGLRELYAMDISRAPSVTAFSKSSFQESCQISHNPDIVKEKENKGIFSFFQRSKKKREQTASAPATPLVSKHRPSFTRSNTISKPYISNTLPSDAPKKRRAPLPPMPTSQGAAQGQERRASCVERSTSVDDTDKSSSEGFMVRTGSLQLSGSTSVGTSSLKRTKRKAPAPPSKPSLTETDEGSSAAAHGLPLEDGIVPDSISEVSSPEGMSSPAGVSSDYSLEEIDEKEELMEASKDQAGSVKSPTIASASTDMIITAENDPDSALSISDGETSPGSKGNTPEGRNPEGQGPHHPVECLIGNENNVSDSIKDLKTLSPNQESVIQNEVVVCATSTDYVKNRPREMEATIEGEAQKKVGDVEAERLSGSPAGRMDDVQSSRENHLTASPGPDQKSNQPRVEKTKMQDAAIQATPACSTFDGNHEAHNSPDLRVDETAQTLGSSTSTQHSSASFQDSVNASREVRSQGTSTYVQDRLPVKEAACTYGNNDALSPIDGSGKNPAASSLKNFPLYRQDNHPKPKPSNEITREYIPKIGMTTYKIVPPKSLEVVKDWDSEAAGKKDNQKTLAVAQKHAIETMTETAVQAEALVTSKNSQQPQPDRTPKPSSGTEHPLHRTVSSPVGTEMNPPKPPRMTTDTGTIPFAPNLEDINNILESKFRSRASNPQAKPSSFFLQMQKRASGHYVTSAAAKSVHTAPGPTPKEPTIKEVQRDPQLPPEQCLSPLSERTHSAPLPNISKADDNRIQKPAETSPPPVAPKPMALPAETSPPAVAPKPMAFPAETSLPPVSPKPMALPTEASSSPISPKPMAPPAEASIPPVVPKPMAPPAEASPLPVAPKPMAFPAETSLPPVAPKPMALPTEASPPPVAPKPLALPGSQGASLNLKTLKTFGAPRPYNSSAPSPFALAVVKRSQSFSKASPESPSEDSSAQPPAAIQDGKTQTVNQPTVGSQHDGVDKQNKPVQNEHSSQRLTPADGPSSFTLQRQSSLNFQSSDPEHIRQSLLTAIRSGEAAAKLKRVTVPSNRISVNGKSGLSQPMSIDAQDSC", "length": 1310 }, "evidence": [ { "id": "A0A8V1A8V7", "url": "https://omabrowser.org/oma/group/A0A8V1A8V7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q3UMF0-1", "protein_name": "Cordon-bleu protein-like 1", "gene_name": "Cobll1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDRSVPDPLPRSAPRTPAMQPAGSAGKRRFMKMFHAHSKNDFVRIKNHKFLPLHICQSRKTKGKAPLPPAETKGTDVSSAEDPVESTAVVTEQQDNMIDKDIELSVVLPGDILKSTTVHGSKPMMDLLVFLCAQYHLNPSSHTIDLLSAEENLIKFKPNTPIGMLDVEKVILKPKSLDKKKPTPIIPEKTVRVVINFKKTQKTIVRVSPHAPLQDLAPIICSKCEFDPLHTVLLKDYQAQEPLDLTKSLNDLGLRELYAMDISRESCQISHNPDIVKEKENKGIFSFFQRSKKKREQTASAPATPLVSKHRPSFTRSNTISKPYISNTLPSDAPKKRRAPLPPMPTSQGAAQGQERRASCVERSTSVDDTDKSSSEAIMVRTGSLQLSSTSIGTSSLKRTKRKAPAPPSKTPLAQTDERNSAMAHGLPLEDGIAPDSMLELSSPEGMSTPEGSLGPGFLSQEQCAVPKPPDEISEGPGTPETAVASLTSGVSSDYSLEEIDEKEELSEASKDPAGSISVKSPDIASASTDMRITVEKDPDSALGISDGETSPSSKGKTQEGRSTEGQGPYHPVVGHIGNEDRVSDSIKDMKTLGPNQESVVQNEIMVCATSTDYVKNRPGKMETTIEGEGEALKKASDMETDRLSGSPACRMDNVKSSRENHLTASPGPDQKLNQPGVEKTKMQDAAIQATPARGTFDGNHEVSNSSDPRADETVQTSDGSISAQHSSASLQDSVNASREFRSQGTSTYVQDRLPEKEPACTYGNNVPLSPVDGSNKNPAASYLKNFPLYRQDSNPKPKPSNEITREYIPKIGMTTYKIVPPKSLEMAKDWESEAMGRKDDQKMLPVGQRHTIENMTETSMQTEVPATSKSSQQPQPDLKPKPSSGTERHLHRTLSSPTGTETNPPKAPRVTTDTGTIPFAPNLEDINNILESKFRSRASNPQAKPSSFFLQMQKRASGHYVTSAAAKSVHTAPGPAPKEPTIKEVQRDPQLSPEQHPSSLSERTHSAPLPNISKADDDIIQKPAETSPPPVAPKPMTLRAETSPPPVFPKPMTLPAETSPPPVFPKPMTLPAETSLPLVFPKPMTLRAETSPPPVAAKPVALPGSQGTSLNLKTLKTFGAPRPYSSSGPSPFALAVVKRSQSFSKACPESASEGSSALPPAATQDEKTHTVNKPTVGSQHGDGDKQNNPVQNEHSSQVLTPADGPSFTLKRQSSLTFQSSDPEHVRQSLLTAIRSGEAAAKLKRVTVPSNTISVNGKSGLSQSMSIDAQDSR", "length": 1273 }, "evidence": [ { "id": "A0A8V1A8V7", "url": "https://omabrowser.org/oma/group/A0A8V1A8V7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "actin monomer binding", "id": "GO:0003785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003785", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A8V7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8V7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cell cortex", "id": "GO:0005938", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005938", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A8V7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8V7" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A8V7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8V7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1017, "end_pos": 1019, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1055, "end_pos": 1057, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1076, "end_pos": 1078, "annotation": "n_glycosylation_sequon" }, { "start_pos": 392, "end_pos": 394, "annotation": "n_glycosylation_sequon" }, { "start_pos": 498, "end_pos": 500, "annotation": "n_glycosylation_sequon" }, { "start_pos": 586, "end_pos": 588, "annotation": "n_glycosylation_sequon" }, { "start_pos": 698, "end_pos": 700, "annotation": "n_glycosylation_sequon" }, { "start_pos": 701, "end_pos": 703, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1A8V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8V7" }, { "id": "PF09469", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09469" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Cordon-bleu ubiquitin-like", "eco_id": "ECO_0000259", "start_pos": 139, "end_pos": 225, "start_aa": "Lys", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 17 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1017, "end_pos": 1019 }, { "start_pos": 1055, "end_pos": 1057 }, { "start_pos": 1076, "end_pos": 1078 }, { "start_pos": 392, "end_pos": 394 }, { "start_pos": 498, "end_pos": 500 }, { "start_pos": 586, "end_pos": 588 }, { "start_pos": 698, "end_pos": 700 }, { "start_pos": 701, "end_pos": 703 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { 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"n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A8Y4-1", "uniprot_ac": "A0A8V1A8Y4", "uniprot_id": "A0A8V1A8Y4_CHICK", "mass": { "chemical_mass": 134008.0, "monoisotopic_mass": 134008.0 }, "refseq": {}, "gene_names": [ { "name": "NCKAP1L", "type": "recommended", "evidence": [ { "id": "A0A8V1A8Y4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8Y4" } ] } ], "protein_names": [ { "name": "NCK associated protein 1 like", "type": "synonym", "evidence": [ { "id": "A0A8V1A8Y4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8Y4/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A8Y4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8Y4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NCKAP1L", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8Y4", "locus": { "chromosome": "34", "start_pos": 708238, "end_pos": 717836, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010025685", "url": "https://www.ensembl.org/id/ENSGALG00010025685" } ] } } ], "crossref": [ { "id": "A0A8V1A8Y4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A8Y4", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR019137", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019137", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZYV1", "url": "https://www.orthodb.org/?gene=A0A8V0ZYV1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A402", "url": "https://www.orthodb.org/?gene=A0A8V1A402", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A8Y4", "url": "https://www.orthodb.org/?gene=A0A8V1A8Y4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12093", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12093", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12093:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12093:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF09735", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09735", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-2029482", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2029482", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-4420097", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4420097", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5663213", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5663213", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-6798695", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9013149", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013149", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9013404", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013404", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9013423", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013423", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZYV1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYV1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZYV1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYV1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A402", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A402", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A402-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A402-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A8Y4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8Y4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A8Y4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8Y4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MADATWPWPALHGCDQCHRATAFALPGTSVTGLQPVLHVTQLWWHPTVSASDVGSITWPRPQPRKFRKGKLVLGNKFAEKLTILNERGRGVLVRIYNIKKTCSDPKTRPSFLCDKAMEPSIKFINKKFPNLDVRSSTQHLGPVHKDKGDIVRALAPYYYSFVDVLEFRDHVYELLNTIDANQCFFDIHVNYDFTKSYLDLIVTYVSLVLLLARTEDRRVLIGMYHCAHEMSHGASDSSFARLGQMVLEYDHPLKKLTEEFGPHSKAVTSALLSLHFLFARRNQGSEQWRSDQLLSLLSTAGTMLSPASSDTMACEYLSLEVMERWILMGFLVCPGALGASPQCLELWRLALQGSLYVTLLRDEALQIHKVTEELLSSLKGYGKRVADLKECKEHAVAHSGSLHRGRRAYLRGAVRELEALLEDQPGLLGPKALFVFMALSFCRDEVSWLLRHAEHVTKTKTPEDFADNHIAEILFLMEQLRSLVRRQVGVLRRYHVQYLARFDALVLSEIIQNLSVCPEEESIILSSFVSSLSSLSDKGVDDKEQFDFTPLRLDWFRLQAYTSVAKAVLPLSTNPDVGRIMNLIVFHTKLLDSLEELLAEVSDLSDLCFFPRPLEKMFVATMEEPSMLRYSIAFPLLCNHFSHCVHPMCPEEHPQLQATALGLCNKFLEEMARQACVCIMDACAEQHNLSERLLPKHCASTVSKARNKKTLKHPSKKGEPERGKPGAESQRKDRSVTTNMDKLHLTLAELSLSLNHVPNFTVFEHTVTPAEYLSSHLEARFTKAIVAMACYSPATQEVARPSEVLVGLGAYITFIQSLTHFVGLDTARIIRSVLLQQTQPRDASGEQTLTTIYTNWYLEALLRQASTGAIVLAPALQAFTTVPREGEPSFSAAEFSDVSEMRALAELIGPYGMKFLSDNLMWHVSSQVAELKKLVNENMDTLVQLRSSSCKPEQMAALLPRLTSADNVLKRMTIIGEILSFRAMAQQGLREVFSHHCPFLMGPIECLTDVVTPDTDIQVTLSIFELASAAGIPCEIDPALVNVLAGSKMDGSSSEEDYKVACLLLVFVAVSLPMLASDPASIYNTEMDGYNNNIHCLAKAIIHVSAALFTLHNKNIETHLKEFLLLASVSLLQLGQETDKLRARNREAVCLLMQLIVAESSFLTVDMLESCFPYVLLRNAYREVCRENLLSRLPPH", "length": 1196, "header": "tr|A0A8V1A8Y4-1|A0A8V1A8Y4_CHICK Isoform 1 of NCK associated protein 1 like OS=Gallus gallus OX=9031 GN=NCKAP1L PE=1 SV=1 CANONICAL=A0A8V1A8Y4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZYV1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8Y4/entry#A0A8V0ZYV1-1", "sequence": { "sequence": 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"length": 1080, "header": "tr|A0A8V0ZYV1-1|A0A8V1A8Y4_CHICK Computationally mapped isoform of NCK associated protein 1 like OS=Gallus gallus OX=9031 GN=NCKAP1L PE=1 SV=1 CANONICAL=A0A8V1A8Y4-1" }, "locus": { "chromosome": "34", "start_pos": 716863, "end_pos": 708658, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010062721.1", "url": "https://www.ensembl.org/id/ENSGALT00010062721.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038771.1", "url": "https://www.ensembl.org/id/ENSGALP00010038771.1" } ] } }, { "isoform_ac": "A0A8V1A402-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8Y4/entry#A0A8V1A402-1", "sequence": { "sequence": 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"length": 551, "header": "tr|A0A8V1A4H2-1|A0A8V1A6V6_CHICK Computationally mapped isoform of Zinc finger protein 76 OS=Gallus gallus OX=9031 GN=ZNF76 PE=4 SV=1 CANONICAL=A0A8V1A6V6-1" }, "locus": { "chromosome": "26", "start_pos": 4170412, "end_pos": 4162761, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063094.1", "url": "https://www.ensembl.org/id/ENSGALT00010063094.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038944.1", "url": "https://www.ensembl.org/id/ENSGALP00010038944.1" } ] } }, { "isoform_ac": "A0A8V1A6V6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6V6/entry#A0A8V1A6V6-1", "sequence": { "sequence": "MPVAGPRCAAVGRRTRVPRPGLWQRWALLCGELRRGLRPCSAPQGGEKVIEEQVTETEDENTVYIHPVIVQKDFVAFEDGQPVVSEDRGMAYISKEGFDSSTSEAVQPEDGSTTNIHSPAIVLPDSPILEVQAETGQEENDDAFDVGTINDLKQYANMHLQEQEVHSNEKRIRPVRKAFHCGYIGCGRIYTTAQHLKVHERSHTGDRPYACRFPSCGKTFATAYGQKTHMKIHTSEKPFKCPEDSCSKAFRASGDLQKHIRTHTGVRPFKCPFEYCDRSFTTSHILRVHIRTHTGERPYTCPEPMCGRSFTSVTNYKNHIRIHTGEKPYACPVPGCGKCFTEYSSLYKHQVVHTRSRPYSCKVCGKAYSQKSTLGTHKCSGRSEPEATVESEEFLCEQQQLEVAAEEGSPMESQHVAFPSEMEKDKDEEEYDDGMPTEVSLISQDETEQISLSQEDLQALGSAVSVVIQSSALAMPEEELVGGDMHTMTVVNADGIETQPVTIVTSGAVVSEESAITSLCHQQVALLATTNGTHIAVQLEEQQSLEDAISMAAAAIQHEPVTLDAAVTENGC", "length": 572, "header": "tr|A0A8V1A6V6-1|A0A8V1A6V6_CHICK Isoform 1 of Zinc finger protein 76 OS=Gallus gallus OX=9031 GN=ZNF76 PE=4 SV=1 CANONICAL=A0A8V1A6V6-1" }, "locus": { "chromosome": "26", "start_pos": 4170858, "end_pos": 4162761, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063104.1", "url": "https://www.ensembl.org/id/ENSGALT00010063104.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038951.1", "url": "https://www.ensembl.org/id/ENSGALP00010038951.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-212436", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-212436", "resource": "Reactome", "description": "Generic Transcription Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A6V6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6V6" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A6V6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6V6" } ], "pmid": "" } ] }, { "name": "Biological 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"https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A6V6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6V6" } ], "pmid": "" }, { "name": "transcription cis-regulatory region binding", "id": "GO:0000976", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000976", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A6V6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6V6" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A6V6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6V6" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A6V6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6V6" } ], "pmid": "" }, { "name": "DNA-binding transcription repressor activity, RNA polymerase II-specific", "id": "GO:0001227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001227", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A6V6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6V6" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A6V6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6V6" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A6V6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6V6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 531, "end_pos": 533, "annotation": 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[], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", 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"field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A9P4-1", "uniprot_ac": "A0A8V1A9P4", "uniprot_id": "A0A8V1A9P4_CHICK", "mass": { "chemical_mass": 55220.0, "monoisotopic_mass": 55220.0 }, "refseq": {}, "gene_names": [ { "name": "EIF2B3", "type": "recommended", "evidence": [ { "id": "A0A8V1A9P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9P4" } ] } ], "protein_names": [ { "name": "Translation initiation factor eIF2B subunit gamma", "type": "recommended", "evidence": [ { "id": "A0A8V1A9P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9P4/entry#names_and_taxonomy" } ] }, { "name": "eIF2B GDP-GTP exchange factor subunit gamma", "type": "synonym", "evidence": [ { "id": "A0A8V1A9P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9P4/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Acts as a component of the translation initiation factor 2B (eIF2B) complex, which catalyzes the exchange of GDP for GTP on the eukaryotic initiation factor 2 (eIF2) complex gamma subunit. Its guanine nucleotide exchange factor activity is repressed when bound to eIF2 complex phosphorylated on the alpha subunit, thereby limiting the amount of methionyl-initiator methionine tRNA available to the ribosome and consequently global translation is repressed.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZZF7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZF7#function" }, { "database": "UniProtKB", "id": "ARBA00045373", "url": "https://www.uniprot.org/uniprotkb/ARBA00045373#function" }, { "database": "UniProtKB", "id": "A0A8V1A9N3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9N3#function" }, { "database": "UniProtKB", "id": "A0A8V1A9N8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9N8#function" }, { "database": "UniProtKB", "id": "A0A8V1AC05", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC05#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9P4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9P4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "EIF2B3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9P4", "locus": { "chromosome": "8", "start_pos": 20511175, "end_pos": 20605529, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010025913", "url": "https://www.ensembl.org/id/ENSGALG00010025913" } ] } } ], "crossref": [ { "id": "A0A8V1A9P4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A9P4", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd04198", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04198", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd04652", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04652", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "424587", "url": "https://www.ncbi.nlm.nih.gov/gene/424587", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR005835", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005835", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011004", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011004", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025877", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025877", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029044", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029044", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051960", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051960", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056764", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056764", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:424587", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424587", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZZF7", "url": "https://www.orthodb.org/?gene=A0A8V0ZZF7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A6Z7", "url": "https://www.orthodb.org/?gene=A0A8V1A6Z7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A9N3", "url": "https://www.orthodb.org/?gene=A0A8V1A9N3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A9N8", "url": "https://www.orthodb.org/?gene=A0A8V1A9N8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A9P4", "url": "https://www.orthodb.org/?gene=A0A8V1A9P4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AC05", "url": "https://www.orthodb.org/?gene=A0A8V1AC05", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45989", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45989", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45989:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45989:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00483", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00483", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12804", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12804", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25084", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25084", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-72731", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72731", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZZF7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZF7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZZF7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZF7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A6Z7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6Z7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A6Z7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6Z7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A9N3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9N3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A9N3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9N3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A9N8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9N8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A9N8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9N8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A9P4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9P4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A9P4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9P4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AC05", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC05", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AC05-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC05-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEFQAVVMAAGGGSRMTDLTSSIPKPLLPVGNRPLLWYPLNLLERAGFEGEAVPGLGRRAGGSPCALPPSWHHLRRSFFHLVMFARCAALAEEVIVITRKEIQKMLSLDTKMKLDFVYISDNVDMGTADSLRHIHQKIKTDVLVLSCDLITDVDLYKVVDLFRTHDATLSMLMKKAPEPTEVAPGQKGKKKPVEQRDFIGVDDTGKRLLFMANEADLDEELVIKRSILQKHPRMHIRTGLMDAHLYCLKKYVVDFLVENRTITSLRSELIPHLVRKQFSSPTSLQQGLDNKEEGRKKKEQASLDIYSFIKEDNSLLKPAPDNSCWNDHRGDMNETLHEGKVRCYVHIMKEGLCCRVNTLALYIEANRQVPKLLLNLGLEEPLVHGTAQITDRGMVGSDSIIGSSTQIGEKTSIKHSIIGSACTIKDKVKITNCIIMNSVTIEEGCCLQGSVICNNAVIEKGADIKDCLIGSDQRLETKAKHVNEVIVGTEQLMEI", "length": 495, "header": "tr|A0A8V1A9P4-1|A0A8V1A9P4_CHICK Isoform 1 of Translation initiation factor eIF2B subunit gamma OS=Gallus gallus OX=9031 GN=EIF2B3 PE=1 SV=1 CANONICAL=A0A8V1A9P4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZZF7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9P4/entry#A0A8V0ZZF7-1", "sequence": { "sequence": "MEFQAVVMAAGGGSRMTDLTSSIPKPLLPVGNRPLLWYPLNLLERAGFEEVIVITRKEIQKMLSLDTKMKLDFVYISDNVDMGTADSLRHIHQKIKTDVLVLSCDLITDVDLYKVVDLFRTHDATLSMLMKKAPEPTEVAPGQKGKKKPVEQRDFIGVDDTGKRLLFMANEADLDEELVIKRSILQNVRQRSKDEYGALCGLIQSVPLWKNFVSGIPLVNPRHPRMHIRTGLMDAHLYCLKKYVVDFLVENRTITSLRSELIPHLVRKQFSSPTSLQQGLDNKEEGRKKKEQASLDIYSFIKEDNSLLKPAPDNSCWNDHRGDMNETLHEGKVRCYVHIMKEGLCCRVNTLALYIEANRQVPKLLLNLGLEEPLVHGTAQITDRGMVGSDSIIGSSTQIGEKTSIKHSIIGSACTIKDKVKITNCIIMNSVTIEEGCCLQGSVICNNAVIEKGADIKDCLIGSDQRLETKAKHVNEVIVGTEQLMEI", "length": 487, "header": "tr|A0A8V0ZZF7-1|A0A8V1A9P4_CHICK Computationally mapped isoform of Translation initiation factor eIF2B subunit gamma OS=Gallus gallus OX=9031 GN=EIF2B3 PE=1 SV=1 CANONICAL=A0A8V1A9P4-1" }, "locus": { "chromosome": "8", "start_pos": 20605033, "end_pos": 20511340, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063174.1", "url": "https://www.ensembl.org/id/ENSGALT00010063174.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038993.1", "url": "https://www.ensembl.org/id/ENSGALP00010038993.1" } ] } }, { "isoform_ac": "A0A8V1A6Z7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9P4/entry#A0A8V1A6Z7-1", "sequence": { "sequence": "MRSALQAHAHCAPAPPLWFCQRGAGRRRAAERSGEVIVITRKEIQKMLSLDTKMKLDFVYISDNVDMGTADSLRHIHQKIKTDVLVLSCDLITDVDLYKVVDLFRTHDATLSMLMKKAPEPTEVAPGQKGKKKPVEQRDFIGVDDTGKRLLFMANEADLDEELVIKRSILQKHPRMHIRTGLMDAHLYCLKKYVVDFLVENRTITSLRSELIPHLVRKQFSSPTSLQQGLDNKEEGRKKKEQASLDIYSFIKEDNSLLKPAPDNSCWNDHRGDMNETLHEGKVRCYVHIMKEGLCCRVNTLALYIEANRQVPKLLLNLGLEEPLVHGTAQITDRGMVGSDSIIGSSTQIGEKTSIKHSIIGSACTIKDKVKITNCIIMNSVTIEEGCCLQGSVICNNAVIEKGADIKDCLIGSDQRLETKAKHVNEVIVGTEQLMEI", "length": 437, "header": "tr|A0A8V1A6Z7-1|A0A8V1A6Z7_CHICK Computationally mapped isoform of Translation initiation factor eIF2B subunit gamma OS=Gallus gallus OX=9031 GN=EIF2B3 PE=1 SV=1 CANONICAL=A0A8V1A9P4-1" }, "locus": { "chromosome": "8", "start_pos": 20605330, "end_pos": 20511340, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063179.1", "url": "https://www.ensembl.org/id/ENSGALT00010063179.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038997.1", "url": "https://www.ensembl.org/id/ENSGALP00010038997.1" } ] } }, { "isoform_ac": "A0A8V1A9N3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9P4/entry#A0A8V1A9N3-1", "sequence": { "sequence": "MEFQAVVMAAGGGSRMTDLTSSIPKPLLPVGNRPLLWYPLNLLERAGFEEVIVITRKEIQKMLSLDTKMKLDFVYISDNVDMGTADSLRHIHQKIKTDVLVLSCDLITDVDLYKVVDLFRTHDATLSMLMKKAPEPTEVAPGQKGKKKPVEQRDFIGVDDTGKRLLFMANEADLDEELVIKRSILQKHPRMHIRTGLMDAHLYCLKKYVVDFLVENRTITSLRSELIPHLVRKQFSSPTSLQQGLDNKEEGRKKKEQASLDIYSFIKEDNSLLKPAPDNSCWNDHRGDMNETLHEGKVRCYVHIMKEGLCCRVNTLALYIEANRQVPKLLLNLGLEEPLVHGTAQITDRGMVGSDSIIGSSTQIGEKTSIKHSIIGSACTIKDKVKITNCIIMNSVTIEEGCCLQGSVICNNAVIEKGADIKDCLIGSDQRLETKGK", "length": 437, "header": "tr|A0A8V1A9N3-1|A0A8V1A9N3_CHICK Computationally mapped isoform of Translation initiation factor eIF2B subunit gamma OS=Gallus gallus OX=9031 GN=EIF2B3 PE=1 SV=1 CANONICAL=A0A8V1A9P4-1" }, "locus": { "chromosome": "8", "start_pos": 20605033, "end_pos": 20522302, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063165.1", "url": "https://www.ensembl.org/id/ENSGALT00010063165.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038986.1", "url": "https://www.ensembl.org/id/ENSGALP00010038986.1" } ] } }, { "isoform_ac": "A0A8V1A9N8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9P4/entry#A0A8V1A9N8-1", "sequence": { "sequence": "MEFQAVVMAAGGGSRMTDLTSSIPKPLLPVGNRPLLWYPLNLLERAGFEEVIVITRKEIQKMLSLDTKMKLDFVYISDNVDMGTADSLRHIHQKIKTDVLVLSCDLITDVDLYKVVDLFRTHDATLSMLMKKAPEPTEVAPGQKGKKKPVEQRDFIGVDDTGKRLLFMANEADLDEELVIKRSILQKHPRMHIRTGLMDAHLYCLKKYVVDFLVENRTITSLRSELIPHLVRKQFSSPTSLQQGLDNKEEGRKKKEQASLDIYSFIKEDNSLLKPAPDNSCWNDHRGDMNETLHEGKVRCYVHIMKEGLCCRVNTLALYIEANRQVPKLLLNLGLEEPLVHGTAQITDRGMVGSDSIIGSSTQIGEKTSIKHSIIGSACTIKDKVKITNCIIMNSVTIEEGCCLQGSVICNNAVIEKGADIKDCLIGSDQRLETKEQFLIKPLLE", "length": 445, "header": "tr|A0A8V1A9N8-1|A0A8V1A9N8_CHICK Computationally mapped isoform of Translation initiation factor eIF2B subunit gamma OS=Gallus gallus OX=9031 GN=EIF2B3 PE=1 SV=1 CANONICAL=A0A8V1A9P4-1" }, "locus": { "chromosome": "8", "start_pos": 20605033, "end_pos": 20512455, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063171.1", "url": "https://www.ensembl.org/id/ENSGALT00010063171.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038991.1", "url": "https://www.ensembl.org/id/ENSGALP00010038991.1" } ] } }, { "isoform_ac": "A0A8V1A9P4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9P4/entry#A0A8V1A9P4-1", "sequence": { "sequence": "MEFQAVVMAAGGGSRMTDLTSSIPKPLLPVGNRPLLWYPLNLLERAGFEGEAVPGLGRRAGGSPCALPPSWHHLRRSFFHLVMFARCAALAEEVIVITRKEIQKMLSLDTKMKLDFVYISDNVDMGTADSLRHIHQKIKTDVLVLSCDLITDVDLYKVVDLFRTHDATLSMLMKKAPEPTEVAPGQKGKKKPVEQRDFIGVDDTGKRLLFMANEADLDEELVIKRSILQKHPRMHIRTGLMDAHLYCLKKYVVDFLVENRTITSLRSELIPHLVRKQFSSPTSLQQGLDNKEEGRKKKEQASLDIYSFIKEDNSLLKPAPDNSCWNDHRGDMNETLHEGKVRCYVHIMKEGLCCRVNTLALYIEANRQVPKLLLNLGLEEPLVHGTAQITDRGMVGSDSIIGSSTQIGEKTSIKHSIIGSACTIKDKVKITNCIIMNSVTIEEGCCLQGSVICNNAVIEKGADIKDCLIGSDQRLETKAKHVNEVIVGTEQLMEI", "length": 495, "header": "tr|A0A8V1A9P4-1|A0A8V1A9P4_CHICK Isoform 1 of Translation initiation factor eIF2B subunit gamma OS=Gallus gallus OX=9031 GN=EIF2B3 PE=1 SV=1 CANONICAL=A0A8V1A9P4-1" }, "locus": { "chromosome": "8", "start_pos": 20605033, "end_pos": 20511340, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063177.1", "url": "https://www.ensembl.org/id/ENSGALT00010063177.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038996.1", "url": "https://www.ensembl.org/id/ENSGALP00010038996.1" } ] } }, { "isoform_ac": "A0A8V1AC05-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9P4/entry#A0A8V1AC05-1", "sequence": { "sequence": "MEFQAVVMAAGGGSRMTDLTSSIPKPLLPVGNRPLLWYPLNLLERAGFEEVIVITRKEIQKMLSLDTKMKLDFVYISDNVDMGTADSLRHIHQKIKTDVLVLSCDLITDVDLYKVVDLFRTHDATLSMLMKKAPEPTEVAPGQKGKKKPVEQRDFIGVDDTGKRLLFMANEADLDEELVIKRSILQKTITSLRSELIPHLVRKQFSSPTSLQQGLDNKEEGRKKKEQASLDIYSFIKEDNSLLKPAPDNSCWNDHRGDMNETLHEGKVRCYVHIMKEGLCCRVNTLALYIEANRQVPKLLLNLGLEEPLVHGTAQITDRGMVGSDSIIGSSTQIGEKTSIKHSIIGSACTIKDKVKITNCIIMNSVTIEEGCCLQGSVICNNAVIEKGADIKDCLIGSDQRLETKAKHVNEVIVGTEQLMEI", "length": 422, "header": "tr|A0A8V1AC05-1|A0A8V1AC05_CHICK Computationally mapped isoform of Translation initiation factor eIF2B subunit gamma OS=Gallus gallus OX=9031 GN=EIF2B3 PE=1 SV=1 CANONICAL=A0A8V1A9P4-1" }, "locus": { "chromosome": "8", "start_pos": 20605033, "end_pos": 20511340, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063175.1", "url": "https://www.ensembl.org/id/ENSGALT00010063175.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038994.1", "url": "https://www.ensembl.org/id/ENSGALP00010038994.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:424587", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424587", "resource": "KEGG Pathway" }, { "id": "R-GGA-72731", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72731", "resource": "Reactome", "description": "Recycling of eIF2:GDP" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9P4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9P4" } ], "pmid": "" }, { "name": "eukaryotic translation initiation factor 2B complex", "id": "GO:0005851", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005851", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9P4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9P4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "translation initiation factor activity", "id": "GO:0003743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003743", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9P4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9P4" } ], "pmid": "" }, { "name": "GTPase regulator activity", "id": "GO:0030695", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030695", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9P4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9P4" } ], "pmid": "" }, { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9P4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9P4" } ], "pmid": "" }, { "name": "translation factor activity, RNA binding", "id": "GO:0008135", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008135", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9P4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9P4" } ], "pmid": "" }, { "name": "nucleotidyltransferase activity", "id": "GO:0016779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016779", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9P4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9P4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "central nervous system development", "id": "GO:0007417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007417", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9P4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9P4" } ], "pmid": "" }, { "name": "cytoplasmic translational initiation", "id": "GO:0002183", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002183", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9P4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9P4" } ], "pmid": "" }, { "name": "T cell receptor signaling pathway", "id": "GO:0050852", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050852", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9P4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9P4" } ], "pmid": "" }, { "name": "oligodendrocyte development", "id": "GO:0014003", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014003", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9P4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9P4" } ], "pmid": "" }, { "name": "positive regulation of translational initiation", "id": "GO:0045948", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045948", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9P4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9P4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 259, "end_pos": 261, "annotation": "n_glycosylation_sequon" }, { "start_pos": 333, "end_pos": 335, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1A9P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9P4" }, { "id": "PF25084", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25084" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EIF2B subunit epsilon/gamma LbH", "eco_id": "ECO_0000259", "start_pos": 388, "end_pos": 477, "start_aa": "Gln", "end_aa": "Thr", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1A9P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9P4" }, { "id": "PF12804", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12804" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "MobA-like NTP transferase", "eco_id": "ECO_0000259", "start_pos": 5, "end_pos": 163, "start_aa": "Ala", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 259, "end_pos": 261 }, { "start_pos": 333, "end_pos": 335 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A9Q4-1", "uniprot_ac": "A0A8V1A9Q4", "uniprot_id": "A0A8V1A9Q4_CHICK", "mass": { "chemical_mass": 50954.0, "monoisotopic_mass": 50954.0 }, "refseq": { "ac": "XP_015131033", "name": "transmembrane protein 116 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015131033" }, "gene_names": [ { "name": "TMEM116", "type": "recommended", "evidence": [ { "id": "A0A8V1A9Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9Q4" } ] }, { "name": "TMEM116", "type": "synonym", "evidence": [ { "id": "XP_015131033", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015131033" } ] } ], "protein_names": [ { "name": "Transmembrane protein 116", "type": "synonym", "evidence": [ { "id": "A0A8V1A9Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9Q4/entry#names_and_taxonomy" } ] }, { "name": "transmembrane protein 116 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_015131033", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015131033" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052546.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 1, 2022 this sequence version replaced XP_015131033.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015131033", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015131033" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9Q4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9Q4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TMEM116", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9Q4", "locus": { "chromosome": "15", "start_pos": 6258437, "end_pos": 6275879, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010025924", "url": "https://www.ensembl.org/id/ENSGALG00010025924" } ] } } ], "crossref": [ { "id": "A0A8V1A9Q4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A9Q4", "database": "AlphaFoldDB", "categories": [] }, { "id": "416881", "url": "https://www.ncbi.nlm.nih.gov/gene/416881", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022343", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022343", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "YARCVES", "url": "https://omabrowser.org/oma/group/YARCVES/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZZG8", "url": "https://www.orthodb.org/?gene=A0A8V0ZZG8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A9Q4", "url": "https://www.orthodb.org/?gene=A0A8V1A9Q4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AC22", "url": "https://www.orthodb.org/?gene=A0A8V1AC22", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23112", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23112", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23112:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23112:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "XP_015131033", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015131033", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZZG8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZG8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZZG8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZG8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A9Q4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9Q4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A9Q4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9Q4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AC22", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC22", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AC22-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC22-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGRAVSVCSKGGRCGEAKQGRLGSAAGGETVRVCRSVERGNPCEPRSAAQIPPPLFPDLCPALKRPRARGPGRGQAGRGAVRSRGGARAVLGAPRAARGSAAVPMAIPEAAASRPEGGWQEVYSALQWIHFTMAMLSVTGSSSIITYAIFQNVVRSPEVRPLFYLSLSDLFLGMCWIAGALLYSTPTSKQDLICYNLQALGQVFYVASFLYTANYTWHLYMDLKVKYNQNLNRMPPTVADYASCIGRVATILSSLIPFLLMVPVFCLGNSSNCYQNFSQKHGCLLMHTEMAEPTNELLTLSGSVCQAMHFYGIGVFLVSFLISFIAILVVLIQARGLYKRFVNSTGFLGDQQWAMIKMVEQRVVFYPIAFFCCWAPAVLLGILKLTASTSSKIYMALLVLQALTAASQGLLNCIVYGWTQHVFLSLKRNICRDVDTQTPLLRSQKKFYASTLPASPPDTEVSTSTLL", "length": 467, "header": "tr|A0A8V1A9Q4-1|A0A8V1A9Q4_CHICK Isoform 1 of Transmembrane protein 116 OS=Gallus gallus OX=9031 GN=TMEM116 PE=4 SV=1 CANONICAL=A0A8V1A9Q4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZZG8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9Q4/entry#A0A8V0ZZG8-1", "sequence": { "sequence": "MLLWQRVENPQENSIAQPFLFAFVTEACVSCNKQHTHIYLEVRQHCLHLTAWRNHGWGFRKSARKICSFYRRFQVFYVASFLYTANYTWHLYMDLKVKYNQNLNRMPPTVADYASCIGRVATILSSLIPFLLMVPVFCLGNSSNCYQNFSQKHGCLLMHTEMAEPTNELLTLSGSVCQAMHFYGIGVFLVSFLISFIAILVVLIQARGLYKRFVNSTGFLGDQQWAMIKMVEQRVVFYPIAFFCCWAPAVLLGILKLTASTSSKIYMALLVLQALTAASQGLLNCIVYGWTQHVFLSLKRNICRDVDTQTPLLRSQKKFYASTLPASPPDTEVSTSTLL", "length": 339, "header": "tr|A0A8V0ZZG8-1|A0A8V1A9Q4_CHICK Computationally mapped isoform of Transmembrane protein 116 OS=Gallus gallus OX=9031 GN=TMEM116 PE=4 SV=1 CANONICAL=A0A8V1A9Q4-1" }, "locus": { "chromosome": "15", "start_pos": 6268247, "end_pos": 6263440, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063188.1", "url": "https://www.ensembl.org/id/ENSGALT00010063188.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039003.1", "url": "https://www.ensembl.org/id/ENSGALP00010039003.1" } ] } }, { "isoform_ac": "A0A8V1A9Q4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9Q4/entry#A0A8V1A9Q4-1", "sequence": { "sequence": "MGRAVSVCSKGGRCGEAKQGRLGSAAGGETVRVCRSVERGNPCEPRSAAQIPPPLFPDLCPALKRPRARGPGRGQAGRGAVRSRGGARAVLGAPRAARGSAAVPMAIPEAAASRPEGGWQEVYSALQWIHFTMAMLSVTGSSSIITYAIFQNVVRSPEVRPLFYLSLSDLFLGMCWIAGALLYSTPTSKQDLICYNLQALGQVFYVASFLYTANYTWHLYMDLKVKYNQNLNRMPPTVADYASCIGRVATILSSLIPFLLMVPVFCLGNSSNCYQNFSQKHGCLLMHTEMAEPTNELLTLSGSVCQAMHFYGIGVFLVSFLISFIAILVVLIQARGLYKRFVNSTGFLGDQQWAMIKMVEQRVVFYPIAFFCCWAPAVLLGILKLTASTSSKIYMALLVLQALTAASQGLLNCIVYGWTQHVFLSLKRNICRDVDTQTPLLRSQKKFYASTLPASPPDTEVSTSTLL", "length": 467, "header": "tr|A0A8V1A9Q4-1|A0A8V1A9Q4_CHICK Isoform 1 of Transmembrane protein 116 OS=Gallus gallus OX=9031 GN=TMEM116 PE=4 SV=1 CANONICAL=A0A8V1A9Q4-1" }, "locus": { "chromosome": "15", "start_pos": 6275680, "end_pos": 6263440, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063192.1", "url": "https://www.ensembl.org/id/ENSGALT00010063192.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039006.1", "url": "https://www.ensembl.org/id/ENSGALP00010039006.1" } ] } }, { "isoform_ac": "A0A8V1AC22-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9Q4/entry#A0A8V1AC22-1", "sequence": { "sequence": "MGRAVSVCSKGGRCGEAKQGRLGSAAGGETVYSALQWIHFTMAMLSVTGSSSIITYAIFQNVVRSPEVRPLFYLSLSDLFLGMCWIAGALLYSTPTSKQDLICYNLQALGQVFYVASFLYTANYTWHLYMDLKVKYNQNLNRMPPTVADYASCIGRVATILSSLIPFLLMVPVFCLGNSSNCYQNFSQKHGCLLMHTEMAEPTNELLTLSGSVCQAMHFYGIGVFLVSFLISFIAILVVLIQARGLYKRFVNSTGFLGDQQWAMIKMVEQRVVFYPIAFFCCWAPAVLLGILKLTASTSSKIYMALLVLQVVLAEQRDARYFSSGTHVRLMQIFFSPHRVPSLMTPASEVSRPTWYSVPQHQVSPTGVWMMVE", "length": 373, "header": "tr|A0A8V1AC22-1|A0A8V1AC22_CHICK Computationally mapped isoform of Transmembrane protein 116 OS=Gallus gallus OX=9031 GN=TMEM116 PE=4 SV=1 CANONICAL=A0A8V1A9Q4-1" }, "locus": { "chromosome": "15", "start_pos": 6275680, "end_pos": 6258503, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063196.1", "url": "https://www.ensembl.org/id/ENSGALT00010063196.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039009.1", "url": "https://www.ensembl.org/id/ENSGALP00010039009.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9Q4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9Q4" } ], "pmid": "" }, { "name": "adenylate cyclase-activating G protein-coupled receptor signaling pathway", "id": "GO:0007189", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007189", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9Q4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9Q4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9Q4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9Q4" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9Q4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9Q4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9Q4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9Q4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 214, "end_pos": 216, "annotation": "n_glycosylation_sequon" }, { "start_pos": 269, "end_pos": 271, "annotation": "n_glycosylation_sequon" }, { "start_pos": 276, "end_pos": 278, "annotation": "n_glycosylation_sequon" }, { "start_pos": 343, "end_pos": 345, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1A9Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9Q4" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 140, "end_pos": 416, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 214, "end_pos": 216 }, { "start_pos": 269, "end_pos": 271 }, { "start_pos": 276, "end_pos": 278 }, { "start_pos": 343, "end_pos": 345 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A9P9-1", "uniprot_ac": "A0A8V1A9P9", "uniprot_id": "A0A8V1A9P9_CHICK", "mass": { "chemical_mass": 24573.0, "monoisotopic_mass": 24573.0 }, "refseq": {}, "gene_names": [ { "name": "GTSF1", "type": "recommended", "evidence": [ { "id": "A0A8V1A9P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9P9" } ] } ], "protein_names": [ { "name": "Gametocyte specific factor 1", "type": "synonym", "evidence": [ { "id": "A0A8V1A9P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9P9/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9P9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9P9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "GTSF1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9P9", "locus": { "chromosome": "27", "start_pos": 685937, "end_pos": 674705, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010025920", "url": "https://www.ensembl.org/id/ENSGALG00010025920" } ] } } ], "crossref": [ { "id": "A0A8V1A9P9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A9P9", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR022776", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022776", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051591", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051591", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZZH2", "url": "https://www.orthodb.org/?gene=A0A8V0ZZH2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A9P9", "url": "https://www.orthodb.org/?gene=A0A8V1A9P9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A9Q9", "url": "https://www.orthodb.org/?gene=A0A8V1A9Q9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AC17", "url": "https://www.orthodb.org/?gene=A0A8V1AC17", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21402", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21402", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21402:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21402:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05253", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05253", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZZH2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZH2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZZH2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZH2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A9P9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9P9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A9P9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9P9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A9Q9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9Q9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A9Q9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9Q9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AC17", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC17", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AC17-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC17-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "QQQRCTAGVQRRIRFFFPCGSEHDVSSVTWGKHRDELSACGLQQLPDLAFETTEHQLCERRGCDDDPERLIQCPYDKQHQIRACRFPYHLVKCRKSHPEVAKLLATCPFNARHLVPQADLGDHISKCRDKGFIEHDIAYCSSGFQRDEVNAVSTWQAPPCDEDWETELLEQPNSPFVWGMTNSGINSCSVTSGQKNYLPSSVRAPESSPYTASWKD", "length": 216, "header": "tr|A0A8V1A9P9-1|A0A8V1A9P9_CHICK Isoform 1 of Gametocyte specific factor 1 OS=Gallus gallus OX=9031 GN=GTSF1 PE=4 SV=1 CANONICAL=A0A8V1A9P9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZZH2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9P9/entry#A0A8V0ZZH2-1", "sequence": { "sequence": "CHYGPSSSSVPKVGPKNHGRRVCPSPERFAEDDPERLIQCPYDKQHQIRACRFPYHLVKCRKSHPEVAKLLATCPFNARHLVPQADLGDHISKCRDKGFIEHDIAYCSSGFQRDEVNAVSTWQAPPCDEDWETELLEQPNSPFVWGMTNSGINSCSVTSGQKNYLPSSVRAPESSPYTASWKD", "length": 183, "header": "tr|A0A8V0ZZH2-1|A0A8V1A9P9_CHICK Computationally mapped isoform of Gametocyte specific factor 1 OS=Gallus gallus OX=9031 GN=GTSF1 PE=4 SV=1 CANONICAL=A0A8V1A9P9-1" }, "locus": { "chromosome": "27", "start_pos": 684053, "end_pos": 676879, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063195.1", "url": "https://www.ensembl.org/id/ENSGALT00010063195.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039008.1", "url": "https://www.ensembl.org/id/ENSGALP00010039008.1" } ] } }, { "isoform_ac": "A0A8V1A9P9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9P9/entry#A0A8V1A9P9-1", "sequence": { "sequence": "QQQRCTAGVQRRIRFFFPCGSEHDVSSVTWGKHRDELSACGLQQLPDLAFETTEHQLCERRGCDDDPERLIQCPYDKQHQIRACRFPYHLVKCRKSHPEVAKLLATCPFNARHLVPQADLGDHISKCRDKGFIEHDIAYCSSGFQRDEVNAVSTWQAPPCDEDWETELLEQPNSPFVWGMTNSGINSCSVTSGQKNYLPSSVRAPESSPYTASWKD", "length": 216, "header": "tr|A0A8V1A9P9-1|A0A8V1A9P9_CHICK Isoform 1 of Gametocyte specific factor 1 OS=Gallus gallus OX=9031 GN=GTSF1 PE=4 SV=1 CANONICAL=A0A8V1A9P9-1" }, "locus": { "chromosome": "27", "start_pos": 684053, "end_pos": 678838, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063184.1", "url": "https://www.ensembl.org/id/ENSGALT00010063184.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039001.1", "url": "https://www.ensembl.org/id/ENSGALP00010039001.1" } ] } }, { "isoform_ac": "A0A8V1A9Q9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9P9/entry#A0A8V1A9Q9-1", "sequence": { "sequence": "MEAEDDLDDPERLIQCPYDKQHQIRACRFPYHLVKCRKSHPEVAKLLATCPFNARHLVPQADLGDHISKCRDKGFIEHDIAYCSSGFQRDEVNAVSTWQAPPCDEDWETELLEQPNSPFVWGMTNSGINSCSVTSGQKNYLPSSVRAPESSPYTASWKDSVLCDNYMDRRDTI", "length": 173, "header": "tr|A0A8V1A9Q9-1|A0A8V1A9Q9_CHICK Computationally mapped isoform of Gametocyte specific factor 1 OS=Gallus gallus OX=9031 GN=GTSF1 PE=4 SV=1 CANONICAL=A0A8V1A9P9-1" }, "locus": { "chromosome": "27", "start_pos": 684168, "end_pos": 674839, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063199.1", "url": "https://www.ensembl.org/id/ENSGALT00010063199.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039011.1", "url": "https://www.ensembl.org/id/ENSGALP00010039011.1" } ] } }, { "isoform_ac": "A0A8V1AC17-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9P9/entry#A0A8V1AC17-1", "sequence": { "sequence": "WKKFSLASYDPERLIQCPYDKQHQIRACRFPYHLVKCRKSHPEVAKLLATCPFNARHLVPQADLGDHISKCRDKGFIEHDIAYCSSGFQRDEVNAVSTWQAPPCDEDWETELLEQPNSPFVWGMTNSGINSVTSGQKNYLPSSVRAPESSPYTASWKD", "length": 158, "header": "tr|A0A8V1AC17-1|A0A8V1AC17_CHICK Computationally mapped isoform of Gametocyte specific factor 1 OS=Gallus gallus OX=9031 GN=GTSF1 PE=4 SV=1 CANONICAL=A0A8V1A9P9-1" }, "locus": { "chromosome": "27", "start_pos": 684053, "end_pos": 679135, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063189.1", "url": "https://www.ensembl.org/id/ENSGALT00010063189.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039004.1", "url": "https://www.ensembl.org/id/ENSGALP00010039004.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9P9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9P9" } ], "pmid": "" }, { "name": "tRNA binding", "id": "GO:0000049", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000049", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9P9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9P9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1A9P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9P9" }, { "id": "PS51800", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51800" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CHHC U11-48K-type", "eco_id": "ECO_0000259", "start_pos": 70, "end_pos": 97, "start_aa": "Leu", "end_aa": "His", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": 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0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AA90-1", "uniprot_ac": "A0A8V1AA90", "uniprot_id": "A0A8V1AA90_CHICK", "mass": { "chemical_mass": 88156.0, "monoisotopic_mass": 88156.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "SRCR domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8V1AA90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA90/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AA90", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA90" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA90", "locus": {} } ], "crossref": [ { "id": "A0A8V1AA90", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AA90", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR001190", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001190", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036772", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036772", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR19331", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19331", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19331:SF487", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19331:SF487", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR48071", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48071", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR48071:SF15", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48071:SF15", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR48071:SF27", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48071:SF27", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00530", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00530", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-3000471", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3000471", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZZZ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZZ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZZZ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZZ0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A580", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A580", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A580-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A580-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AA90", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA90", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AA90-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA90-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MWWPLECRGSPCLGSLLSLWGPSPHGHSSEELRLVDGGGRCAGRVEVKHEGEWGSVCSYDFDWDIRGAGVVCRQLGCGTVAHASPYAPFGQGKGRIWLHPFLCQGTETTLQNCPNFGWGNHYCGHEWDVGVICTGEVVGCDGNRVLGALGRLRLADGGRPCEGRVEVKLQGRWGTVADDAWDMDDAEVVCQQLGCGSAAGAYLASRFRLVDSPIMMAVIDCQGDERHPGQCPVEVLGQPACPPGHTAAVNCSGGCGGRGDPQQVGRSTAQELRLVDGGGRCAGRVEVKHEGEWGSVCSYDFDWDIRVAGMVCRQLGCGTVAHASPYAPFGQGKGRIWLHPFLCQGTETTLQNCPHFECQDPWAGLRLIPDAEALELRLADGRGPCDGRVEVKLRGRWGTVADDAWDMDDAEVVCQQLGCGSAASTKFTWRISQVSSPVMLVRVNCNGTEKAIWDCNIQGWGPYSTPLDYSTSVVCQGESWAHAAKRKAHCPHSPSPAAHLSWQDSPGWPEGTASAQGGWRCGRARPGSASAMATWTSWPPRWSAESWAVVLHWPYLGLSCLGYEQGYSGMVPSSAMAPSPPCPLAQSGLPTSRTAPNPLPSSAPVSAGSAGLHQPQTMWWPGEFPTPPTPAPLSAAAYSGFRLADGVSVCDGRVEVEARGVWGTLCATAWDLPDAHVLCHHLGCGTAVSLPPPGHFGMGTGMLRSDAFRCSGSERHPGQCPVEVLGQPTCPPGHTAAVNCSGGCGGRGDPQQVGSTAQAHGTARLLQVSPSPCGCTVGRAIVTGGWRWPCAPESGPVCLWGCGTTALPPWCAGSWAAVCLRKSMLCQPMARAP", "length": 833, "header": "tr|A0A8V1AA90-1|A0A8V1AA90_CHICK Isoform 1 of SRCR domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1AA90-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZZZ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA90/entry#A0A8V0ZZZ0-1", "sequence": { "sequence": "AEGVPVWGHSCPCGDPLLMGTSCRHGTGTPRLSLLTGVPTGSEELRLVDGGGRCAGRVEVKHEGEWGSVCSYDFDWDIRVAGMVCRQLGCGTVAHASPYAPFGQGKGRIWLHPFLCQGTETTLQNCPHFGWGNHYCGHEWDVGVICTGLRLIPDAEALELRLADGRGPCDGRVEVKLRGRWGTVADDAWDMDDAEVVCQQLGCGSAASTKFTWRISQVSSPVMLVRVNCNGTEKLGTCSQEESPLPTFPQPSSPPLLAGFSRLAGGDSECSGRLEVRQGQTWVSVCHGHVDLMAAQVVCRELGCGTALALSGAELFGVRAGLFWNGAFECNGTEPSLSACTKRPPHIQNCTQPATIICSRKCWLCRATSAPNHVVAWGISHSTNSSTSLCCSLQRVPAGRRSLSVRWASGGGGTRGVGDPVCHCLGPA", "length": 428, "header": "tr|A0A8V0ZZZ0-1|A0A8V1AA90_CHICK Computationally mapped isoform of SRCR domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1AA90-1" }, "locus": { "chromosome": "5", "start_pos": 16417008, "end_pos": 16415192, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063466.1", "url": "https://www.ensembl.org/id/ENSGALT00010063466.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039180.1", "url": "https://www.ensembl.org/id/ENSGALP00010039180.1" } ] } }, { "isoform_ac": "A0A8V1A580-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA90/entry#A0A8V1A580-1", "sequence": { "sequence": "MQHGWPQSPARAPRSWPSPAQVSALRKLRLVGGRGRCAGRVEVYSEGTWGTICQDSWTQQDATVVCRQLGCGWALEAPGSERFGPGTGTLWLGAGGCAGTEDALWHCPAPVQRGCRRGGGAGAVRDSSEATSPAPGSSLQDRDTSANGFVHAHCPLTAAIRSPWGLTLPITSLTSCGASLLCRWNDSCMWLVLTPGPHVRENTPSYLCCREGTGLHVPRCRRTKAAAGPHSDVVASRVQRESPEELRLVDGGGRCAGRVEVKHEGEWGSVCSYDFDWDIRVAGMVCRQLGCGTVAHASPYAPFGQGKGRIWLHPFLCQGTETTLQNCPHFECQDPWAGLRLIPDAEALELRLADGRGPCDGRVEVKLRGRWGTVADDAWDMDDAEVVCQQLGCGSAASTKFTWRISQVSSPVMLVRVNCNGTEKAIWDCNIQGWGPYSTPLDYSTSVVCQGESWAHAAKRKAHCPHSPSPAAHLSWQDSPGWPEGTASAQGGWRCGRARPGSASAMATWTSWPPRWSAESWAVVLHWPYLGLSCLGYEQGYSGMVPSSAMAPSPPCPLAQSGLPTSRTAPNPLPSSAPVSAGSAGLHQPQTMWWPGEFPTPPTPAPLSAAAYSGFRLADGVSVCDGRVEVEARGVWGTLCATAWDLPDAHVLCHHLGCGTAVSLPPPGHFGMGTGMLRSDAFRCSGSERHPGQCPVEVLGQPTCPPGHTAAVNCSGGCGGRGDPQQVGSTAQAHGTARLLQVSPSPCGCTVGRAIVTGGWRWPCAPESGPVCLWGCGTTALPPWCAGSWAAVCLRKSMLCQPMARAP", "length": 807, "header": "tr|A0A8V1A580-1|A0A8V1AA90_CHICK Computationally mapped isoform of SRCR domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1AA90-1" }, "locus": { "chromosome": "5", "start_pos": 16417489, "end_pos": 16411566, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063486.1", "url": "https://www.ensembl.org/id/ENSGALT00010063486.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039192.1", "url": "https://www.ensembl.org/id/ENSGALP00010039192.1" } ] } }, { "isoform_ac": "A0A8V1AA90-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA90/entry#A0A8V1AA90-1", "sequence": { "sequence": "MWWPLECRGSPCLGSLLSLWGPSPHGHSSEELRLVDGGGRCAGRVEVKHEGEWGSVCSYDFDWDIRGAGVVCRQLGCGTVAHASPYAPFGQGKGRIWLHPFLCQGTETTLQNCPNFGWGNHYCGHEWDVGVICTGEVVGCDGNRVLGALGRLRLADGGRPCEGRVEVKLQGRWGTVADDAWDMDDAEVVCQQLGCGSAAGAYLASRFRLVDSPIMMAVIDCQGDERHPGQCPVEVLGQPACPPGHTAAVNCSGGCGGRGDPQQVGRSTAQELRLVDGGGRCAGRVEVKHEGEWGSVCSYDFDWDIRVAGMVCRQLGCGTVAHASPYAPFGQGKGRIWLHPFLCQGTETTLQNCPHFECQDPWAGLRLIPDAEALELRLADGRGPCDGRVEVKLRGRWGTVADDAWDMDDAEVVCQQLGCGSAASTKFTWRISQVSSPVMLVRVNCNGTEKAIWDCNIQGWGPYSTPLDYSTSVVCQGESWAHAAKRKAHCPHSPSPAAHLSWQDSPGWPEGTASAQGGWRCGRARPGSASAMATWTSWPPRWSAESWAVVLHWPYLGLSCLGYEQGYSGMVPSSAMAPSPPCPLAQSGLPTSRTAPNPLPSSAPVSAGSAGLHQPQTMWWPGEFPTPPTPAPLSAAAYSGFRLADGVSVCDGRVEVEARGVWGTLCATAWDLPDAHVLCHHLGCGTAVSLPPPGHFGMGTGMLRSDAFRCSGSERHPGQCPVEVLGQPTCPPGHTAAVNCSGGCGGRGDPQQVGSTAQAHGTARLLQVSPSPCGCTVGRAIVTGGWRWPCAPESGPVCLWGCGTTALPPWCAGSWAAVCLRKSMLCQPMARAP", "length": 833, "header": "tr|A0A8V1AA90-1|A0A8V1AA90_CHICK Isoform 1 of SRCR domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1AA90-1" }, "locus": { "chromosome": "5", "start_pos": 16417489, "end_pos": 16409192, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063472.1", "url": "https://www.ensembl.org/id/ENSGALT00010063472.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039183.1", "url": "https://www.ensembl.org/id/ENSGALP00010039183.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 626, "start_aa": "Thr", "end_pos": 626, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr626", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 629, "start_aa": "Thr", "end_pos": 629, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr629", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-GGA-3000471", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3000471", "resource": "Reactome", "description": "Scavenging by Class B Receptors" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AA90", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA90" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AA90", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA90" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AA90", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA90" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AA90", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA90" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 250, "end_pos": 252, "annotation": "n_glycosylation_sequon" }, { "start_pos": 446, "end_pos": 448, "annotation": "n_glycosylation_sequon" }, { "start_pos": 739, "end_pos": 741, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AA90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA90" }, { "id": "PS50287", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50287" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SRCR", "eco_id": "ECO_0000259", "start_pos": 32, "end_pos": 134, "start_aa": "Leu", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 626, 629 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 250, "end_pos": 252 }, { "start_pos": 446, "end_pos": 448 }, { "start_pos": 739, "end_pos": 741 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AAL3-1", "uniprot_ac": "A0A8V1AAL3", "uniprot_id": "A0A8V1AAL3_CHICK", "mass": { "chemical_mass": 56882.0, "monoisotopic_mass": 56882.0 }, "refseq": { "ac": "XP_004942748", "name": "zinc finger protein 385B isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004942748" }, "gene_names": [ { "name": "ZNF385B", "type": "recommended", "evidence": [ { "id": "A0A8V1AAL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAL3" } ] }, { "name": "ZNF385B", "type": "synonym", "evidence": [ { "id": "XP_004942748", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004942748" } ] } ], "protein_names": [ { "name": "Zinc finger protein 385B", "type": "recommended", "evidence": [ { "id": "A0A8V1AAL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAL3/entry#names_and_taxonomy" } ] }, { "name": "Zinc finger protein 533", "type": "synonym", "evidence": [ { "id": "A0A8V1AAL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAL3/entry#names_and_taxonomy" } ] }, { "name": "zinc finger protein 385B isoform X2", "type": "synonym", "evidence": [ { "id": "XP_004942748", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004942748" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052538.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004942748.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004942748", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004942748" } ] }, { "annotation": "May play a role in p53/TP53-mediated apoptosis.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAL3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAL3#function" }, { "database": "UniProtKB", "id": "ARBA00060301", "url": "https://www.uniprot.org/uniprotkb/ARBA00060301#function" }, { "database": "UniProtKB", "id": "A0A8V1ACV2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACV2#function" }, { "database": "UniProtKB", "id": "A0A8V1A0B3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0B3#function" }, { "database": "UniProtKB", "id": "A0A8V1A0B8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0B8#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAL3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAL3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ZNF385B", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAL3", "locus": { "chromosome": "7", "start_pos": 14589506, "end_pos": 14437095, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010026154", "url": "https://www.ensembl.org/id/ENSGALG00010026154" } ] } } ], "crossref": [ { "id": "A0A8V1AAL3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AAL3", "database": "AlphaFoldDB", "categories": [] }, { "id": "424124", "url": "https://www.ncbi.nlm.nih.gov/gene/424124", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003604", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003604", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051845", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051845", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:424124", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424124", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NYPEDGI", "url": "https://omabrowser.org/oma/group/NYPEDGI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A0B3", "url": "https://www.orthodb.org/?gene=A0A8V1A0B3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A0B8", "url": "https://www.orthodb.org/?gene=A0A8V1A0B8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A7W2", "url": "https://www.orthodb.org/?gene=A0A8V1A7W2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AAL3", "url": "https://www.orthodb.org/?gene=A0A8V1AAL3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ACV2", "url": "https://www.orthodb.org/?gene=A0A8V1ACV2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23067", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23067", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23067:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23067:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12874", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12874", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004942748", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004942748", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1A0B3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0B3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A0B3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0B3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A0B8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0B8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A0B8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0B8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A7W2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7W2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A7W2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7W2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AAL3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAL3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AAL3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAL3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ACV2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACV2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ACV2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACV2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFVNVRRKTQLVSTCSWYAVSTAKPSCYAVFSTKRICVSWVHLHHMGMKRPLSPDRVFEDGIMNQPAVLRSSEEKGLKNDRQDYQLGKEKKKILFSFCEVCNIQLNSAAQAQVHYNGKSHLKRVKQLNNGKLPTSTAPGTLFPSTSTGTTALPTLVRAPTLMMQPSLDIKPFMSFPVDSSSAVGFFPNFNTMDPVQKAVINHTFGVSIPPKKKQVISCNVCQLRFNSDSQAEAHYKGSKHAKKVKALEATKNKPKVGSSKDSTKANPSCSTPVTANISDKSEDKGKVKSNGASQHSSTEVGAFLPKAGVAAVAPVTPAVSSNSTNGAPSTTSESEEEKAKKLLYCSLCKVAVNSLSQLEAHNTGSKHKTMVEARNGAGPIKSYPRPGSRLKVQNGSKGSGLQNKTFHCEICDVHVNSEIQLKQHISSRRHKDRVAGKPMKPKYSPYNKLQRSPSILAAKLAFQKDMIKPLAPAFLSSPLAAAVSSALSLPARPAASLFQAPAIPPALLRPGHGPIRATPASILFAPY", "length": 527, "header": "tr|A0A8V1AAL3-1|A0A8V1AAL3_CHICK Isoform 1 of Zinc finger protein 385B OS=Gallus gallus OX=9031 GN=ZNF385B PE=4 SV=1 CANONICAL=A0A8V1AAL3-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A0B3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAL3/entry#A0A8V1A0B3-1", "sequence": { "sequence": "MWSGLPSRGTTALPTLVRAPTLMMQPSLDIKPFMSFPVDSSSAVGFFPNFNTMDPVQKAVINHTFGVSIPPKKKQVISCNVCQLRFNSDSQAEAHYKGSKHAKKVKALEATKNKPKVGSSKDSTKANPSCSTPVTANISDKSEDKGKVKSNGASQHSSTEVGAFLPKAGVAAVAPVTPAVSSNSTNGAPSTTSESEEEKAKKLLYCSLCKVAVNSLSQLEAHNTGSKHKTMVEARNGAGPIKSYPRPGSRLKVQNGSKGSGLQNKTFHCEICDVHVNSEIQLKQHISSRRHKDRVAGKPMKPKYSPYNKLQRSPSILAAKLAFQKDMIKPLAPAFLSSPLAAAVSSALSLPARPAASLFQAPAIPPALLRPGHGPIRATPASILFAPY", "length": 388, "header": "tr|A0A8V1A0B3-1|A0A8V1AAL3_CHICK Computationally mapped isoform of Zinc finger protein 385B OS=Gallus gallus OX=9031 GN=ZNF385B PE=4 SV=1 CANONICAL=A0A8V1AAL3-1" }, "locus": { "chromosome": "7", "start_pos": 14588306, "end_pos": 14474253, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063701.1", "url": "https://www.ensembl.org/id/ENSGALT00010063701.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039310.1", "url": "https://www.ensembl.org/id/ENSGALP00010039310.1" } ] } }, { "isoform_ac": "A0A8V1A0B8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAL3/entry#A0A8V1A0B8-1", "sequence": { "sequence": "MKRPLSPDRVFEDGIMNQPAVLRSSEEKGLKNDRQDYQLGKEKKKILFSFCEVCNIQLNSAAQAQVHYNGKSHLKRVKQLNNGKLPTSTAPGTLFPSTSTGTTALPTLVRAPTLMMQPSLDIKPFMSFPVDSSSAVGFFPNFNTMDPVQKAVINHTFGVSIPPKKKQVISCNVCQLRFNSDSQAEAHYKGSKHAKKVKALEATKNKPKVGSSKDSTKANPSCSTPVTANISDKSEDKGKVKSNGASQHSSTEVGAFLPKAGVAAVAPVTPAVSSNSTNGAPSTTSESEEEKAKKLLYCSLCKVAVNSLSQLEAHNTGSKHKTMVEARNGAGPIKSYPRPGSRLKVQNGSKGSGLQNKTFHCEICDVHVNSEIQLKQHISSRRHKDRVAGKPMKPKYSPYNKLQRSPSILAAKLAFQKDMIKPLAPAFLSSPLAAAVSSALSLPARPAASLFQAPAIPPALLRPGHGPIRATPASILFAPY", "length": 480, "header": "tr|A0A8V1A0B8-1|A0A8V1AAL3_CHICK Computationally mapped isoform of Zinc finger protein 385B OS=Gallus gallus OX=9031 GN=ZNF385B PE=4 SV=1 CANONICAL=A0A8V1AAL3-1" }, "locus": { "chromosome": "7", "start_pos": 14588306, "end_pos": 14467374, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063714.1", "url": "https://www.ensembl.org/id/ENSGALT00010063714.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039315.1", "url": "https://www.ensembl.org/id/ENSGALP00010039315.1" } ] } }, { "isoform_ac": "A0A8V1A7W2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAL3/entry#A0A8V1A7W2-1", "sequence": { "sequence": "MKRPLSPDRVFEDGIMNQPAVLRSSEEKGLKNDRQDYQLGKEKKKILFSFCEVCNIQLNSAAQAQVHYNGKSHLKRVKQLNNGKLPTSTAPGTLFPSTSTGTTALPTLVRAPTLMMQPSLDIKPFMSFPVDSSSAVGFFPNFNTSQAEAHYKGSKHAKKVKALEATKNKPKVGSSKDSTKANPSCSTPVTANISDKSEDKGKVKSNGASQHSSTEVGAFLPKAGVAAVAPVTPAVSSNSTNGAPSTTSESEEEKAKKLLYCSLCKVAVNSLSQLEAHNTGSKHKTMVEARNGAGPIKSYPRPGSRLKVQNGSKGSGLQNKTFHCEICDVHVNSEIQLKQHISSRRHKDRVAGKPMKPKYSPYNKLQRSPSILAAKLAFQKDMIKPLAPAFLSSPLAAAVSSALSLPARPAASLFQAPAIPPALLRPGHGPIRATPASILFAPY", "length": 443, "header": "tr|A0A8V1A7W2-1|A0A8V1A7W2_CHICK Computationally mapped isoform of Zinc finger protein 385B OS=Gallus gallus OX=9031 GN=ZNF385B PE=4 SV=1 CANONICAL=A0A8V1AAL3-1" }, "locus": { "chromosome": "7", "start_pos": 14588306, "end_pos": 14467374, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063712.1", "url": "https://www.ensembl.org/id/ENSGALT00010063712.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039314.1", "url": "https://www.ensembl.org/id/ENSGALP00010039314.1" } ] } }, { "isoform_ac": "A0A8V1AAL3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAL3/entry#A0A8V1AAL3-1", "sequence": { "sequence": "MFVNVRRKTQLVSTCSWYAVSTAKPSCYAVFSTKRICVSWVHLHHMGMKRPLSPDRVFEDGIMNQPAVLRSSEEKGLKNDRQDYQLGKEKKKILFSFCEVCNIQLNSAAQAQVHYNGKSHLKRVKQLNNGKLPTSTAPGTLFPSTSTGTTALPTLVRAPTLMMQPSLDIKPFMSFPVDSSSAVGFFPNFNTMDPVQKAVINHTFGVSIPPKKKQVISCNVCQLRFNSDSQAEAHYKGSKHAKKVKALEATKNKPKVGSSKDSTKANPSCSTPVTANISDKSEDKGKVKSNGASQHSSTEVGAFLPKAGVAAVAPVTPAVSSNSTNGAPSTTSESEEEKAKKLLYCSLCKVAVNSLSQLEAHNTGSKHKTMVEARNGAGPIKSYPRPGSRLKVQNGSKGSGLQNKTFHCEICDVHVNSEIQLKQHISSRRHKDRVAGKPMKPKYSPYNKLQRSPSILAAKLAFQKDMIKPLAPAFLSSPLAAAVSSALSLPARPAASLFQAPAIPPALLRPGHGPIRATPASILFAPY", "length": 527, "header": "tr|A0A8V1AAL3-1|A0A8V1AAL3_CHICK Isoform 1 of Zinc finger protein 385B OS=Gallus gallus OX=9031 GN=ZNF385B PE=4 SV=1 CANONICAL=A0A8V1AAL3-1" }, "locus": { "chromosome": "7", "start_pos": 14588306, "end_pos": 14455540, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063709.1", "url": "https://www.ensembl.org/id/ENSGALT00010063709.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039313.1", "url": "https://www.ensembl.org/id/ENSGALP00010039313.1" } ] } }, { "isoform_ac": "A0A8V1ACV2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAL3/entry#A0A8V1ACV2-1", "sequence": { "sequence": "MYRSSPALDPPEHGATCAPVAKLEMLGAGMKRPLSPDRVFEDGIMNQPAVLRSSEEKGLKNDRQDYQLGKEKKKILFSFCEVCNIQLNSAAQAQVHYNGKSHLKRVKQLNNGKLPTSTAPGTLFPSTSTGTTALPTLVRAPTLMMQPSLDIKPFMSFPVDSSSAVGFFPNFNTMDPVQKAVINHTFGVSIPPKKKQVISCNVCQLRFNSDSQAEAHYKGSKHAKKVKALEATKNKPKVGSSKDSTKANPSCSTPVTANISDKSEDKGKVKSNGASQHSSTEVGAFLPKAGVAAVAPVTPAVSSNSTNGAPSTTSESEEEKAKKLLYCSLCKVAVNSLSQLEAHNTGSKHKTMVEARNGAGPIKSYPRPGSRLKVQNGSKGSGLQNKTFHCEICDVHVNSEIQLKQHISSRRHKDRVAGKPMKPKYSPYNKLQRSPSILAAKLAFQKDMIKPLAPAFLSSPLAAAVSSALSLPARPAASLFQAPAIPPALLRPGHGPIRATPASILFAPY", "length": 509, "header": "tr|A0A8V1ACV2-1|A0A8V1ACV2_CHICK Computationally mapped isoform of Zinc finger protein 385B OS=Gallus gallus OX=9031 GN=ZNF385B PE=4 SV=1 CANONICAL=A0A8V1AAL3-1" }, "locus": { "chromosome": "7", "start_pos": 14588306, "end_pos": 14464533, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063705.1", "url": "https://www.ensembl.org/id/ENSGALT00010063705.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039311.1", "url": "https://www.ensembl.org/id/ENSGALP00010039311.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 316, "start_aa": "Thr", "end_pos": 316, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr316", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 518, "start_aa": "Thr", "end_pos": 518, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr518", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:424124", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424124", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I5Y545-1", "protein_name": "Zinc finger protein 385B", "gene_name": "Zfp385b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNMASFLRGFEEKGLKNDRPGDQFSKEKKKILFSFCDVCNIQLNSAAQAQVHYDGKSHRKRVKQLSDGQPPPPAQGSVPLLASPCPGPGPGPGTNTSTGSACHTTTLPALVRTPTLMMQPSLDIKPFMSFPVDSSSAVGLFPNFNTKRRGLFGTNKFFQMDPVQKAVINHTFGVSIPPKKKQVISCNVCQLRFNSDSQAEAHYTGSKHAKKVKALEATKNKPKMVPSKDSAKANPSCSVRPGTGDSSDKSEDKGKIKATSSSQPSGSEGGSFFLKSGTTPLTLGAIASPSKSTNGAPGSVAESEEEKAKKLLYCSLCKVAVNSLSQLEAHNTGSKHKTMVEARNGAGPIKSYPRPGSRLKVQNGSKGSGLQNKTFHCEICDVHVNSEIQLKQHISSRRHKDRVAGKPLKPKYSPYNKLQRSPSILAAKLAFQKDLMKPLAPTFLSSPLAAAAVSTALSLPPRPSASLFQAAAIPPALLRPGHGPIRATPTSILFAPY", "length": 497 }, "evidence": [ { "id": "A0A8V1AAL3", "url": "https://omabrowser.org/oma/group/A0A8V1AAL3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q569K4-1", "protein_name": "Zinc finger protein 385B", "gene_name": "ZNF385B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNMANFLRGFEEKGIKNDRPEDQLSKEKKKILFSFCEVCNIQLNSAAQAQVHSNGKSHRKRVKQLSDGQPPPPAQASPSSNSSTGSTCHTTTLPALVRTPTLMMQPSLDIKPFMSFPVDSSSAVGLFPNFNTMDPVQKAVINHTFGVSIPPKKKQVISCNVCQLRFNSDSQAEAHYKGSKHAKKVKALDATKNKPKMVPSKDSAKANPSCSITPITGNNSDKSEDKGKLKASSSSQPSSSESGSFLLKSGTTPLPPGAATSPSKSTNGAPGTVVESEEEKAKKLLYCSLCKVAVNSLSQLEAHNTGSKHKTMVEARNGAGPIKSYPRPGSRLKMQNGSKGSGLQNKTFHCEICDVHVNSEIQLKQHISSRRHKDRVAGKPLKPKYSPYNKLQRSPSILAAKLAFQKDMMKPLAPAFLSSPLAAAAAVSSALSLPPRPSASLFQAPAIPPALLRPGHGPIRATPASILFAPY", "length": 471 }, "evidence": [ { "id": "A0A8V1AAL3", "url": "https://omabrowser.org/oma/group/A0A8V1AAL3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6PBT9-1", "protein_name": "Zinc finger protein 385B", "gene_name": "znf385b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MQLQQEKKKLLYSLCDVCNIQLHSAAQAQVHYNGKSHLKRVKQLNNGEVPKASASLAPTSLQSLSSSSSQGSSCHSNTLPTLVRTPSLMMQSGLDMKPFMTFPVESSSPVGLFPNFNTMDPVQKAVINHTFGVSIPPKKKQVISCNICQLRFNSDSQAEAHYKGSKHAKKLKAQESPKNKQKSAVAQDSGTKTITSTSTNTTTTTTTTSSCTAVTASCSDQTEKSTEPLAAHKVPASPQAFVPAPVAPAVALVPSPCKTAPVHASPPTEPTGLAVALKNTSKPAALPTAPSEPSVESEEEKAKKLLYCSLCKVAVNSLSQLEAHNTGSKHKTMLEARNGAGPIKAYPRPGSKLKVQATQLNKGSGLQNKTFHCEICDVHVNSEIQLKQHISSRRHKDRVAGKPTKPKYSPYNKQQRSSSSLAAKLALQNDLVKPISPAFLPSPFSTTTVPSISLHPRPNTSIFQTASLPHSFLRAAPGPIRPTTGSILFAPY", "length": 492 }, "evidence": [ { "id": "A0A8V1AAL3", "url": "https://omabrowser.org/oma/group/A0A8V1AAL3/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8BXJ8-1", "protein_name": "Zinc finger protein 385B", "gene_name": "Znf385b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNMATFLRGFEEKGLKNDRPGDQFSKEKKKILFSFCEVCNIQLNSAAQAQVHYDGKSHRKRVKQLSDGQPPPPVQGSVPLLAGPCPCPGPGPNTSTGSACHTTTLPALVRTPTLMMQPSLDIKPFMSFPVDSSSAVGLFPNFNTMDPVQKAVINHTFGVSIPPKKKQVISCNVCQLRFNSDSQAEAHYKGSKHAKKVKALEATKNKPKMVPSKDSAKANPSCSIRPGTGDSSDKSEDKGKIKATSSSQPSGSEGGSFLLKSGTTPLPLGAIASPSKSTNGAPGSVAESEEEKAKKLLYCSLCKVAVNSLSQLEAHNTGSKHKTMVEARNGAGPIKSYPRPGSRLKVQNGSKGSGLQNKMFHCEICDVHVNSEIQLKQHISSRRHKDRVAGKPLKPKYSPYNKLQRSPSILAAKLAFQKDLMKPLAPTFLSSPLAAAAVSSALSLPPRPSASLFQAAAIPPALLRPGHGPIRATPASILFAPY", "length": 482 }, "evidence": [ { "id": "A0A8V1AAL3", "url": "https://omabrowser.org/oma/group/A0A8V1AAL3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAL3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAL3" } ], "pmid": "" }, { "name": "fibrillar center", "id": "GO:0001650", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001650", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAL3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAL3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAL3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAL3" } ], "pmid": "" }, { "name": "nucleic acid binding", "id": "GO:0003676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAL3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAL3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAL3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAL3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 201, "end_pos": 203, "annotation": "n_glycosylation_sequon" }, { "start_pos": 276, "end_pos": 278, "annotation": "n_glycosylation_sequon" }, { "start_pos": 322, "end_pos": 324, "annotation": "n_glycosylation_sequon" }, { "start_pos": 394, "end_pos": 396, "annotation": "n_glycosylation_sequon" }, { "start_pos": 403, "end_pos": 405, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AAL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAL3" }, { "id": "PS00028", "database": "PROSITE", "url": "https://prosite.expasy.org/PS00028" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 218, "end_pos": 240, "start_aa": "Cys", "end_aa": "His", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 316, 518 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 201, "end_pos": 203 }, { "start_pos": 276, "end_pos": 278 }, { "start_pos": 322, "end_pos": 324 }, { "start_pos": 394, "end_pos": 396 }, { "start_pos": 403, "end_pos": 405 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A879-1", "uniprot_ac": "A0A8V1A879", "uniprot_id": "A0A8V1A879_CHICK", "mass": { "chemical_mass": 46779.0, "monoisotopic_mass": 46779.0 }, "refseq": { "ac": "XP_015142342", "name": "smoothelin-like protein 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015142342" }, "gene_names": [ { "name": "SMTNL1", "type": "recommended", "evidence": [ { "id": "A0A8V1A879", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A879" } ] }, { "name": "SMTNL1", "type": "synonym", "evidence": [ { "id": "XP_015142342", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015142342" } ] } ], "protein_names": [ { "name": "Smoothelin like 1", "type": "synonym", "evidence": [ { "id": "A0A8V1A879", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A879/entry#names_and_taxonomy" } ] }, { "name": "smoothelin-like protein 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015142342", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015142342" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052536.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015142342.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015142342", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015142342" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A879", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A879" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SMTNL1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A879", "locus": {} } ], "crossref": [ { "id": "A0A8V1A879", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A879", "database": "AlphaFoldDB", "categories": [] }, { "id": "101750657", "url": "https://www.ncbi.nlm.nih.gov/gene/101750657", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001715", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001715", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036872", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036872", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050540", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050540", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:101750657", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:101750657", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GAEPEMQ", "url": "https://omabrowser.org/oma/group/GAEPEMQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A0N2", "url": "https://www.orthodb.org/?gene=A0A8V1A0N2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A879", "url": "https://www.orthodb.org/?gene=A0A8V1A879", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23167", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23167", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23167:SF45", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23167:SF45", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00307", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00307", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015142342", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015142342", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1A0N2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0N2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A0N2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0N2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A879", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A879", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A879-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A879-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MESPTTGGAPAPSDTALGDLTQTSTGPTEGMGGGDSGESAAQEEQGAEGGAGGEAAGDAGSEGKAEAAKDCGSEAKGEAAGDAGSNAKGEAAKDAGSEAKGEAAKDAGNEAKGEAAKDAGSEAKGEAVEDAGSEAKGEAAKDAGSEAKEEVAKDAGNEAKGEAAKDDGSEAEAAGDAGKGPAAGQAAEREAEGQARGSAVPQEEAEPGPRPVAAGSTQGRQEPTWLQDEDDELWPEFLPCSPTEGPTSPTTPLSPASPVSPTFPTSPTSPSSPPVSPTSPAAGSTEGSGGSESGVSAVGPRGRVPPRVAAVGRPRMSSRAHGRSAILEKFGGAATGPAPHLKRAGATGSVKAMLLEWCRARTRGYQHVDIQNFSGSWSSGMAFCALIHSFFPDAFDYGSLEPQDRRRNFTLAFTTAEERVDCAQLLEVEDMLRLAVPDAKCIYTYVQELYRSLVAKGLVKTKKR", "length": 464, "header": "tr|A0A8V1A879-1|A0A8V1A879_CHICK Isoform 1 of Smoothelin like 1 OS=Gallus gallus OX=9031 GN=SMTNL1 PE=3 SV=1 CANONICAL=A0A8V1A879-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A0N2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A879/entry#A0A8V1A0N2-1", "sequence": { "sequence": "MESPTTGGAPAPSDTALGDLTQTSTGPTEGMGGGDSGESAAQEEQGAEGGAGGEAAGDAGSEGKAEAAKDCGSEAKGEAAGDAGSNAKGEAAKDAGSEAKGEAAKDAGSEAKGEAVEDAGSEAKGEAAKDAGSEAKEEVAKDAGNEAKGEAAKDDGSEAEAAGDAGKGPAAGQAAEREAEGQARGSAVPQEEAEPGPRPVAAGSTQGRQEPTWLQDEDDELWPEFLPCSPTEGPTSPTTPLSPASPVSPTFPTSPTSPSSPPVSPTSPAAGSTEGSGGSESGVSAVGPRGRVPPRVAAVGRPRMSSRAHGRSAILEKFGGAATGPAPHLKRAGATGSVKAMLLEWCRARTRGYQHVDIQNFSGSWSSGMAFCALIHSFFPDAFDYGSLEPQDRRRNFTLAFTTAEERVDCAQLLEVEDMLRLAVPDAKCIYTYVQELYRSLVAKGLVKTKKR", "length": 452, "header": "tr|A0A8V1A0N2-1|A0A8V1A879_CHICK Computationally mapped isoform of Smoothelin like 1 OS=Gallus gallus OX=9031 GN=SMTNL1 PE=3 SV=1 CANONICAL=A0A8V1A879-1" }, "locus": { "chromosome": "5", "start_pos": 16564790, "end_pos": 16562464, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010064088.1", "url": "https://www.ensembl.org/id/ENSGALT00010064088.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039431.1", "url": "https://www.ensembl.org/id/ENSGALP00010039431.1" } ] } }, { "isoform_ac": "A0A8V1A879-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A879/entry#A0A8V1A879-1", "sequence": { "sequence": "MESPTTGGAPAPSDTALGDLTQTSTGPTEGMGGGDSGESAAQEEQGAEGGAGGEAAGDAGSEGKAEAAKDCGSEAKGEAAGDAGSNAKGEAAKDAGSEAKGEAAKDAGNEAKGEAAKDAGSEAKGEAVEDAGSEAKGEAAKDAGSEAKEEVAKDAGNEAKGEAAKDDGSEAEAAGDAGKGPAAGQAAEREAEGQARGSAVPQEEAEPGPRPVAAGSTQGRQEPTWLQDEDDELWPEFLPCSPTEGPTSPTTPLSPASPVSPTFPTSPTSPSSPPVSPTSPAAGSTEGSGGSESGVSAVGPRGRVPPRVAAVGRPRMSSRAHGRSAILEKFGGAATGPAPHLKRAGATGSVKAMLLEWCRARTRGYQHVDIQNFSGSWSSGMAFCALIHSFFPDAFDYGSLEPQDRRRNFTLAFTTAEERVDCAQLLEVEDMLRLAVPDAKCIYTYVQELYRSLVAKGLVKTKKR", "length": 464, "header": "tr|A0A8V1A879-1|A0A8V1A879_CHICK Isoform 1 of Smoothelin like 1 OS=Gallus gallus OX=9031 GN=SMTNL1 PE=3 SV=1 CANONICAL=A0A8V1A879-1" }, "locus": { "chromosome": "5", "start_pos": 16564790, "end_pos": 16562464, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010064083.1", "url": "https://www.ensembl.org/id/ENSGALT00010064083.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039430.1", "url": "https://www.ensembl.org/id/ENSGALP00010039430.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 247, "start_aa": "Thr", "end_pos": 247, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr247", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 278, "start_aa": 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"go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "actin cytoskeleton organization", "id": "GO:0030036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030036", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A879", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A879" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 372, "end_pos": 374, "annotation": "n_glycosylation_sequon" }, { "start_pos": 408, "end_pos": 410, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1A879", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A879" }, { "id": "PS50021", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50021" } ], "ann_type": "Domain_Extent_Annotation", 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}, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A8K2-1", "uniprot_ac": "A0A8V1A8K2", "uniprot_id": "A0A8V1A8K2_CHICK", "mass": { "chemical_mass": 21693.0, "monoisotopic_mass": 21693.0 }, "refseq": {}, "gene_names": [ { "name": "TNNI1", "type": "recommended", "evidence": [ { "id": "A0A8V1A8K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8K2" } ] } ], "protein_names": [ { "name": "Troponin I, fast skeletal muscle", "type": "recommended", "evidence": [ { "id": "A0A8V1A8K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8K2/entry#names_and_taxonomy" } ] }, { "name": "Troponin I, fast-twitch isoform", "type": "synonym", "evidence": [ { "id": "A0A8V1A8K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8K2/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A8K2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8K2#function" }, { "database": "UniProtKB", "id": "ARBA00001988", "url": "https://www.uniprot.org/uniprotkb/ARBA00001988#function" }, { "database": "UniProtKB", "id": "A0A8V1A110", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A110#function" }, { "database": "UniProtKB", "id": "A0A8V1A646", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A646#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A8K2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8K2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TNNI1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8K2", "locus": { "chromosome": "26", "start_pos": 830769, "end_pos": 820758, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010026560", "url": "https://www.ensembl.org/id/ENSGALG00010026560" } ] } } ], "crossref": [ { "id": "A0A8V1A8K2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A8K2", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR001849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001978", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001978", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038077", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038077", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042832", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042832", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050875", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050875", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A110", "url": "https://www.orthodb.org/?gene=A0A8V1A110", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A646", "url": "https://www.orthodb.org/?gene=A0A8V1A646", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A8K2", "url": "https://www.orthodb.org/?gene=A0A8V1A8K2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13738", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13738", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13738:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13738:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15478", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15478", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15478:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15478:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00992", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00992", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-390522", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-390522", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1A110", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A110", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A110-1", 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OX=9031 GN=TNNI1 PE=3 SV=1 CANONICAL=A0A8V1A8K2-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A110-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8K2/entry#A0A8V1A110-1", "sequence": { "sequence": "MTPEKVLREGLLEKRSGGLLQLWKKKRCLLTEKGLQLFEPKGSRRKELSFARMKAVECVEWKERHIYFTVVMDDSHEIDFRCAQEDPGWNAAITMGLVRFKNQQAIQVVRARHSCRAGDQPSAAMPEPRERKSKITASRKLLLKSLMLAKAKEEWEQEIVDKQSEKERYLSERITPLHTSGLSLSQLQDLCRELHEKVEIVDEERYDIEAKCNHNTREIKDLKLKVLDLRGKFKRPPLRRVRVSADAMLRALLGSKHKVSMDLRANLKSVKKEDTEKERPVEVGDWRKNVEAMSGMEGRKKMFDAAKSPTGQ", "length": 312, "header": "tr|A0A8V1A110-1|A0A8V1A8K2_CHICK Computationally mapped isoform of Troponin I, fast skeletal muscle OS=Gallus gallus OX=9031 GN=TNNI1 PE=3 SV=1 CANONICAL=A0A8V1A8K2-1" }, "locus": { "chromosome": "26", "start_pos": 830312, "end_pos": 820957, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010064530.1", "url": "https://www.ensembl.org/id/ENSGALT00010064530.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039557.1", "url": "https://www.ensembl.org/id/ENSGALP00010039557.1" } ] } }, { "isoform_ac": "A0A8V1A646-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8K2/entry#A0A8V1A646-1", "sequence": { "sequence": "MRRRAFRGEQCWMLGGSEQRGWVTPHSAPPVHTQTHRSPPGLGDQPSAAMPEPRERKSKITASRKLLLKSLMLAKAKEEWEQEIVDKQSEKERYLSERITPLHTSGLSLSQLQDLCRELHEKVEIVDEERYDIEAKCNHNTREIKDLKLKVLDLRGKFKRPPLRRVRVSADAMLRALLGSKHKVSMDLRANLKSVKKEDTEKERPVEVGDWRKNVEAMSGMEGRKKMFDAAKSPTGQ", "length": 237, "header": "tr|A0A8V1A646-1|A0A8V1A8K2_CHICK Computationally mapped isoform of Troponin I, fast skeletal muscle OS=Gallus gallus OX=9031 GN=TNNI1 PE=3 SV=1 CANONICAL=A0A8V1A8K2-1" }, "locus": { "chromosome": "26", "start_pos": 830312, "end_pos": 826665, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010064518.1", "url": "https://www.ensembl.org/id/ENSGALT00010064518.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039554.1", "url": "https://www.ensembl.org/id/ENSGALP00010039554.1" } ] } }, { "isoform_ac": "A0A8V1A8K2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8K2/entry#A0A8V1A8K2-1", "sequence": { "sequence": "MPEPERKSKITASRKLLLKSLMLAKAKEEWEQEIVDKQSEKERYLSERITPLHTSGLSLSQLQDLCRELHEKVEIVDEERYDIEAKCNHNTREIKDLKLKVLDLRGKFKRPPLRRVRVSADAMLRALLGSKHKVSMDLRANLKSVKKEDTEKERPVEVGDWRKNVEAMSGMEGRKKMFDAAKSPTGQ", "length": 187, "header": "tr|A0A8V1A8K2-1|A0A8V1A8K2_CHICK Isoform 1 of Troponin I, fast skeletal muscle OS=Gallus gallus OX=9031 GN=TNNI1 PE=3 SV=1 CANONICAL=A0A8V1A8K2-1" }, "locus": { "chromosome": "26", "start_pos": 830312, "end_pos": 827034, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010064525.1", "url": "https://www.ensembl.org/id/ENSGALT00010064525.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039556.1", "url": "https://www.ensembl.org/id/ENSGALP00010039556.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-390522", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-390522", "resource": "Reactome", "description": "Striated Muscle Contraction" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "skeletal muscle contraction", "id": "GO:0003009", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003009", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A8K2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8K2" } ], "pmid": "" }, { "name": "positive regulation of apoptotic process", "id": "GO:0043065", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043065", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A8K2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8K2" } ], "pmid": "" }, { "name": "cardiac muscle contraction", "id": "GO:0060048", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060048", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A8K2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8K2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A8K2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8K2" } ], "pmid": "" }, { "name": "phosphatidylinositol phosphate binding", "id": "GO:1901981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901981", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A8K2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8K2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "troponin complex", "id": "GO:0005861", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005861", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A8K2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8K2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": 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}, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A8X3-1", "uniprot_ac": "A0A8V1A8X3", "uniprot_id": "A0A8V1A8X3_CHICK", "mass": { "chemical_mass": 26171.0, "monoisotopic_mass": 26171.0 }, "refseq": {}, "gene_names": [ { "name": "TMEM9", "type": "recommended", "evidence": [ { "id": "A0A8V1A8X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8X3" } ] } ], "protein_names": [ { "name": "Transmembrane protein 9", "type": "synonym", "evidence": [ { "id": "A0A8V1A8X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8X3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A8X3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8X3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TMEM9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8X3", "locus": { "chromosome": "26", "start_pos": 951237, "end_pos": 947518, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010025044", "url": "https://www.ensembl.org/id/ENSGALG00010025044" } ] } } ], "crossref": [ { "id": "A0A8V1A8X3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A8X3", "database": "AlphaFoldDB", "categories": [] }, { "id": "421157", "url": "https://www.ncbi.nlm.nih.gov/gene/421157", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR008853", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008853", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "QCTWKCA", "url": "https://omabrowser.org/oma/group/QCTWKCA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A1D1", "url": "https://www.orthodb.org/?gene=A0A8V1A1D1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A3P8", "url": "https://www.orthodb.org/?gene=A0A8V1A3P8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A8X3", "url": "https://www.orthodb.org/?gene=A0A8V1A8X3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13064", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13064", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13064:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13064:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05434", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05434", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1A1D1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1D1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A1D1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1D1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A3P8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3P8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A3P8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3P8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A8X3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8X3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A8X3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8X3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNGAEASREDGPGLSWRNLRLLEGIALSGGFCPVWGCLFPQASTMFARCTWKRASSVLLIALLSCVLSPPAQAAKSSEDIRCKCICPPYRNISGHIYNKNVSQKDCNCLHVVEPMPVPGNDVEAYCLLCECKYEERSTTTIKVVIIIYLSVVGALLLYMAFLVLVDPLIRKPDAYTQPLHNEEENEDSRSLAAAPTPSGARANTVLERVEGAQQRWKRQVQEQRKTVFDRHKMLS", "length": 235, "header": "tr|A0A8V1A8X3-1|A0A8V1A8X3_CHICK Isoform 1 of Transmembrane protein 9 OS=Gallus gallus OX=9031 GN=TMEM9 PE=3 SV=1 CANONICAL=A0A8V1A8X3-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A1D1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8X3/entry#A0A8V1A1D1-1", "sequence": { "sequence": "MLSASTMFARCTWKRASSVLLIALLSCVLSPPAQAAKSSEDIRCKCICPPYRNISGHIYNKNVSQKDCNCLHVVEPMPVPGNDVEAYCLLCECKYEERSTTTIKVVIIIYLSVVGALLLYMAFLVLVDPLIRKPDAYTQPLHNEEENEDSRSLAAAPTPSGARANTVLERVEGAQQRWKRQVQEQRKTVFDRHKMLS", "length": 197, "header": "tr|A0A8V1A1D1-1|A0A8V1A8X3_CHICK Computationally mapped isoform of Transmembrane protein 9 OS=Gallus gallus OX=9031 GN=TMEM9 PE=3 SV=1 CANONICAL=A0A8V1A8X3-1" }, "locus": { "chromosome": "26", "start_pos": 950096, "end_pos": 947933, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010061134.1", "url": "https://www.ensembl.org/id/ENSGALT00010061134.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010037820.1", "url": "https://www.ensembl.org/id/ENSGALP00010037820.1" } ] } }, { "isoform_ac": "A0A8V1A3P8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8X3/entry#A0A8V1A3P8-1", "sequence": { "sequence": "MGAQSRGGACRGAGVARQASTMFARCTWKRASSVLLIALLSCVLSPPAQAAKSSEDIRCKCICPPYRNISGHIYNKNVSQKDCNCLHVVEPMPVPGNDVEAYCLLCECKYEERSTTTIKVVIIIYLSVVGALLLYMAFLVLVDPLIRKPDAYTQPLHNEEENEDSRSLAAAPTPSGARANTVLERVEGAQQRWKRQVQEQRKTVFDRHKMLS", "length": 212, "header": "tr|A0A8V1A3P8-1|A0A8V1A8X3_CHICK Computationally mapped isoform of Transmembrane protein 9 OS=Gallus gallus OX=9031 GN=TMEM9 PE=3 SV=1 CANONICAL=A0A8V1A8X3-1" }, "locus": { "chromosome": "26", "start_pos": 950096, "end_pos": 947526, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010061146.1", "url": "https://www.ensembl.org/id/ENSGALT00010061146.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010037827.1", "url": "https://www.ensembl.org/id/ENSGALP00010037827.1" } ] } }, { "isoform_ac": "A0A8V1A8X3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8X3/entry#A0A8V1A8X3-1", "sequence": { "sequence": "MNGAEASREDGPGLSWRNLRLLEGIALSGGFCPVWGCLFPQASTMFARCTWKRASSVLLIALLSCVLSPPAQAAKSSEDIRCKCICPPYRNISGHIYNKNVSQKDCNCLHVVEPMPVPGNDVEAYCLLCECKYEERSTTTIKVVIIIYLSVVGALLLYMAFLVLVDPLIRKPDAYTQPLHNEEENEDSRSLAAAPTPSGARANTVLERVEGAQQRWKRQVQEQRKTVFDRHKMLS", "length": 235, "header": "tr|A0A8V1A8X3-1|A0A8V1A8X3_CHICK Isoform 1 of Transmembrane protein 9 OS=Gallus gallus OX=9031 GN=TMEM9 PE=3 SV=1 CANONICAL=A0A8V1A8X3-1" }, "locus": { "chromosome": "26", "start_pos": 950096, "end_pos": 947697, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010061141.1", "url": "https://www.ensembl.org/id/ENSGALT00010061141.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010037824.1", "url": "https://www.ensembl.org/id/ENSGALP00010037824.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 196, "start_aa": "Thr", "end_pos": 196, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr196", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A287A166-1", "protein_name": "Transmembrane protein 9", "gene_name": "TMEM9", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MKLLCLVAVVASLLVPPAQANKSSEDIRCKCICPPYRNISGHIYNQNVSQKDCNCLHVVEPMPVPGHDVEAYCLLCECKYEERSTTTIKIIIVIYLSVVGALLLYMAFLMLVDPLIRKPDAYTERLHNEEENEDARSVAAAASFGPRANTVLERVEGAQQRWKLQVQEQRKTVFDRHKMLS", "length": 181 }, "evidence": [ { "id": "A0A8V1A8X3", "url": "https://omabrowser.org/oma/group/A0A8V1A8X3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A9J7G2Z5-1", "protein_name": "Transmembrane protein 9 isoform X1", "gene_name": "Tmem9", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MKLLCLVAVVGSLLVPPAQANKVRESSEDIRCKCICPPYRNISGHIYNQNVSQKDCNCLHVVEPMPVPGHDVEAYCLLCECRYEERSTTTIKVIIVIYLSVVGALLLYMAFLMLVDPLIRKPDAYTEQLHNEEENEDARSMAAAAASIGGPRANTVLERVEGAQQRWKLQVQEQRKTVFDRHKMLS", "length": 186 }, "evidence": [ { "id": "A0A8V1A8X3", "url": "https://omabrowser.org/oma/group/A0A8V1A8X3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q9CR23-1", "protein_name": "Proton-transporting V-type ATPase complex assembly regulator TMEM9", "gene_name": "Tmem9", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKLLCLVAVVGCLLVPPAQANKSSEDIRCKCICPPYRNISGHIYNQNVSQKDCNCLHVVEPMPVPGHDVEAYCLLCECRYEERSTTTIKVIIVIYLSVVGALLLYMAFLMLVDPLIRKPDAYTEQLHNEEENEDARTMATAAASIGGPRANTVLERVEGAQQRWKLQVQEQRKTVFDRHKMLS", "length": 183 }, "evidence": [ { "id": "A0A8V1A8X3", "url": "https://omabrowser.org/oma/group/A0A8V1A8X3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9P0T7-1", "protein_name": "Proton-transporting V-type ATPase complex assembly regulator TMEM9", "gene_name": "TMEM9", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKLLSLVAVVGCLLVPPAEANKSSEDIRCKCICPPYRNISGHIYNQNVSQKDCNCLHVVEPMPVPGHDVEAYCLLCECRYEERSTTTIKVIIVIYLSVVGALLLYMAFLMLVDPLIRKPDAYTEQLHNEEENEDARSMAAAAASLGGPRANTVLERVEGAQQRWKLQVQEQRKTVFDRHKMLS", "length": 183 }, "evidence": [ { "id": "A0A8V1A8X3", "url": "https://omabrowser.org/oma/group/A0A8V1A8X3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "lysosomal membrane", "id": "GO:0005765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005765", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A8X3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8X3" } ], "pmid": "" }, { "name": "multivesicular body membrane", "id": "GO:0032585", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032585", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A8X3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8X3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "positive regulation of canonical Wnt signaling pathway", "id": "GO:0090263", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090263", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A8X3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8X3" } ], "pmid": "" }, { "name": "endosomal lumen acidification", "id": "GO:0048388", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048388", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A8X3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8X3" } ], "pmid": "" }, { "name": "lysosomal lumen acidification", "id": "GO:0007042", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007042", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A8X3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8X3" } ], "pmid": "" }, { "name": "regulation of protein catabolic process", "id": "GO:0042176", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042176", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A8X3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8X3" } ], "pmid": "" }, { "name": "proton-transporting V-type ATPase complex assembly", "id": "GO:0070070", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070070", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A8X3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8X3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 100, "end_pos": 102, "annotation": "n_glycosylation_sequon" }, { "start_pos": 91, "end_pos": 93, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], 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"IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR23235", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23235", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23235:SF120", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23235:SF120", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23235:SF141", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23235:SF141", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A1S3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1S3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A1S3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1S3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A9C1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9C1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A9C1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9C1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AC83", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC83", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AC83-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC83-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPPSLLPRHSPKEGSDHLLEGSTGRNEGDPLPLAGADGEEEKPLLAACDAHLQLPDFCCSLPQDFIPTLEEIEEFLREKAEFLRDGASEQHAAGGKARAESETGLGGSGGHPVPEDGSDGSQPGGAADGNDQGAADGDVPVVLHMQPLQLDNSSLLAQRAVRVTQLVISLQGQNLSLLPQLQPPVTLLDQKYIKIAPQPNPTGPGMLGGVQKQEAAPVCPKAPTAPLHVHKCPHPGCSKVYTKSSHLKAHIRRHTGEKPRGNQKAFWQCSLSSWATKMALPMNASPRKRELLLPPSASSRVGSAIPLLSLPVCPPWLRGSFVPLSLFSFLSVP", "length": 333, "header": "tr|A0A8V1A9C1-1|A0A8V1A9C1_CHICK Isoform 1 of C2H2-type domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1A9C1-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A1S3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9C1/entry#A0A8V1A1S3-1", "sequence": { "sequence": "MPPSLLPRHSPKEGSDHLLEGSTGRNEGDPLPLAGADGEEEKPLLAACDAHLQLPDFCCSLPQDFIPTLEEIEEFLREKAEFLRDGASEQHAAGGKARAESETGLGGSGGHPVPEDGSDGSQPGGAADGNDQGAADGDVPVVLHMQPLQLDNSSLLAQRAVRVTQLVISLQGQNLSLLPQLQPPVTLLDQKYIKIAPQPNPTGPGMLGGVQKQEAAPVCPKAPTAPLHVHKCPHPGCSKVYTKSSHLKAHIRRHTGEKPYSCAWPDCGWR", "length": 270, "header": "tr|A0A8V1A1S3-1|A0A8V1A9C1_CHICK Computationally mapped isoform of C2H2-type domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1A9C1-1" }, "locus": { "chromosome": "26", "start_pos": 2256588, "end_pos": 2255779, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065475.1", "url": "https://www.ensembl.org/id/ENSGALT00010065475.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039829.1", "url": 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"https://www.ensembl.org/id/ENSGALP00010039826.1" } ] } }, { "isoform_ac": "A0A8V1AC83-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9C1/entry#A0A8V1AC83-1", "sequence": { "sequence": "MPPSLLPRHSPKEGSDHLLEGSTGRNEGDPLPLAGADGEEEKPLLAACDAHLQLPDFCCSLPQDFIPTLEEIEEFLREKAEFLRDGASEQHAAGGKARAESETGLGGSGGHPVPEDGSDGSQPGGAADGNDQGAADGDVPVVLHMQPLQLDNSSLLAQRAVRVTQLVISLQGQNLSLLPQLQPPVTLLDQKYIKIAPQPNPTGPGMLGGVQKQEAAPVCPKAPTAPLHVHKCPHPGCSKVYTKSSHLKAHIRRHTGEKPYSCAWPDCGWSRNALWKCR", "length": 278, "header": "tr|A0A8V1AC83-1|A0A8V1AC83_CHICK Computationally mapped isoform of C2H2-type domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1A9C1-1" }, "locus": { "chromosome": "26", "start_pos": 2256588, "end_pos": 2251927, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065477.1", "url": "https://www.ensembl.org/id/ENSGALT00010065477.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039830.1", "url": "https://www.ensembl.org/id/ENSGALP00010039830.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9C1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9C1" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9C1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9C1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9C1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9C1" } ], "pmid": "" }, { "name": "regulation of macromolecule metabolic process", "id": "GO:0060255", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060255", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9C1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9C1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 152, "end_pos": 154, "annotation": "n_glycosylation_sequon" }, { "start_pos": 174, "end_pos": 176, "annotation": "n_glycosylation_sequon" }, { "start_pos": 283, "end_pos": 285, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1A9C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9C1" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 230, "end_pos": 259, "start_aa": "His", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 152, "end_pos": 154 }, { "start_pos": 174, "end_pos": 176 }, { "start_pos": 283, "end_pos": 285 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A6W4-1", "uniprot_ac": "A0A8V1A6W4", "uniprot_id": "A0A8V1A6W4_CHICK", "mass": { "chemical_mass": 247073.0, "monoisotopic_mass": 247073.0 }, "refseq": {}, "gene_names": [ { "name": "CLIP1", "type": "recommended", "evidence": [ { "id": "A0A8V1A6W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6W4" } ] } ], "protein_names": [ { "name": "CAP-Gly domain containing linker protein 1", "type": "synonym", "evidence": [ { "id": "A0A8V1A6W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6W4/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A6W4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6W4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CLIP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6W4", "locus": { "chromosome": "15", "start_pos": 5831016, "end_pos": 5883120, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027040", "url": "https://www.ensembl.org/id/ENSGALG00010027040" } ] } } ], "crossref": [ { "id": "IPR000938", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000938", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032108", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032108", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036859", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036859", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A1U8", "url": "https://www.orthodb.org/?gene=A0A8V1A1U8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A1V2", "url": "https://www.orthodb.org/?gene=A0A8V1A1V2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A6W4", "url": "https://www.orthodb.org/?gene=A0A8V1A6W4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A9E5", "url": "https://www.orthodb.org/?gene=A0A8V1A9E5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ACA5", "url": "https://www.orthodb.org/?gene=A0A8V1ACA5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ACB1", "url": "https://www.orthodb.org/?gene=A0A8V1ACB1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AEC0", "url": "https://www.orthodb.org/?gene=A0A8V1AEC0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AED1", "url": "https://www.orthodb.org/?gene=A0A8V1AED1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR18916", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18916", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR18916:SF44", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18916:SF44", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01302", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01302", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16641", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16641", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF27241", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27241", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-141430", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-141430", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-141444", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-141444", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-2467813", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2467813", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-2500257", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2500257", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5663220", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5663220", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9648025", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9648025", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1A1U8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1U8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A1U8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1U8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A1V2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1V2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A1V2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1V2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A6W4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6W4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A6W4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6W4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A9E5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9E5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A9E5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9E5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ACA5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACA5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ACA5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACA5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ACB1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACB1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ACB1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACB1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AEC0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEC0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AEC0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEC0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AED1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AED1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AED1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AED1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSMLKPSGLKAPSKTIKHGSTLLKAPASVATAPAEKAPSSEKSSSTTTADAHDDFVDDFRVGERVWVNGNKPGFIQFLGETQFAPGQWAGIVLDEPIGKNDGSVAGVRYFQCEPLRGIFTRPSKLSRKVLTEDEANGTQTAHASRATSPTSTSTASAVSASPAALLPSGIPQKTSPLAAKEHSTPSQFSNLSKTASGSVSNLSEAGSLKKGERELKIGDRVLVGGTKAGVVRFLGETDFAKGEWCGVELDEPLGKNDGAVAGTRYFQCQPRYGLFAPVHKVTKIGFPSTTPAKAKTTVRKVVATPAALKRSPSASSLSSLSSVASSVSSKPSRTGLLTETSSRYARKISGTTALQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALVRDGHDRHVLEMEAKMDQLRAMVEAADREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLERKRQISEDPENVATVSEKSRIMELERDLALRVKEVAELRGRLESSKHIDDVDTSLSLLQEISSLQEKMAAAGKEHQREMSSLKEKFESSEEALRKEIKTLSASNERMGKENESLKTKLDHANKENSDVIELWKSKLESAIASHQQAMEELKVSFNKGVGAQTAEFAELKTQMEKVKLDYENEMSNLKLKQENEKSQHLKEIEALKAKLLEVTEEKEQTLENLKAKLESVEDQHLVEMEDTLNKLQEAEIKVKELDVLQAKCNEQTKLIGSLTQQIRASEEKLLDLAALQKANSEGKLEIQKLSEQLQAAEKQIQNLETEKVGGSSKVSNLTKELQGKEQKLLDLEKNLSAVNQVKDSLEKELQLLKEKFTSAVDGAENAQRAMQETINKLNQKEEQFALMSSELEQLKSNLTVMETKLKEREEREQQLTEAKVKLENDIAEIMKSSGDSSAQLMKMNDELRLKERQLEQIQLELTKANEKAVQLQKNVEQTAQKAEQSQQETLKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKYEKETSEMITKHDADIKGFKQNLLDAEEALKAAQKKNDELETQAEELKKQAEQAKSLSSVLASARKEIELMSDKMRDLISEKETLAQERNTLKLEKESLLSQHLEMESKILLVQQDREELWTKNEELNSENKKILKQKEAAEAKSRQESTEKVALISEKSKLLSEIETAQADLLKITQENDALRSSESTLLQQLKELQANKDAVDVACQKHIKEREELEHYQKLLEENDRVIKDKDDVIQRLQSSYDDLARNQRELLQEVSILTAERDSAQEKDLDLKSTHIALKNEIDCLLQTNRSLQSEKEMLLKSREELCVSLANTANENQALKLRKDEMQTELETEREKLEKMTKDNMDLKASLSSLSNFLEEMKSSREASNSEKIHLLQEALFASEQRLLAEREELVNENKAVTEKLTKATADAVLAETAFTEKINELNLEKESVFSKSLQFEKHNEALLREKDELERKYSELLDEKKSLENAFSDMKREQELDFSAKRLLVQENTTLKYSIEALEEELKKKNLENQELIACRSDLSDLLKEAQDARRTLENELAAVSHAKQVLSSSFNTCSSDIEILNRERTELQDKCQKLTGEVENMKENLTVEKKARILDKESFLLERMELQNNIGFLEKEVEEMREKNKEFLTEKELLVQEKEKSETKLEEVIKEKMILYKETEQLASKIEQLKSDFTSLSVSKAELEDVHSCVSVMLDELQHKYEVTEKEKMELVQENESLHAEWKSLVIINEEILKEKEKLSKEYYKLHEKVVALLEQTDADFSCRLLVSEGKHELLLEEMSNLALKLREIERLQAQTFMQKFEADKRAEEVLQTMEKVTKEKDAIHQEKIETLASLENSRQTNEKLQNELDMLKQNNLKNEEELTKSKELLNLENKKVEELKKEFEALKLAAAQKSQQLAALQEENVKLAEELGRSRDEVTSHQKLEEERSVLNNQLLEMKKRESTLKKEIDEERASLQKSISDTSALITQKDEELEKLRNEITVLRGENASAKTLQSVVKTLESDKLKLEEKVKNLEQKLKAKSEQPLTVTSPSGDIAANLLQDESAEDKQQEIDFLNSVIVDLQRRNEELNLKIQRMCEAALNGNEEETINYDSEEEGLSKKTPRLFCDICGCFDLHDTEDCPTQAQMLEEPPHSTYHGSRREERPYCDTCEMFGHWTADCNDDETF", "length": 2175, "header": "tr|A0A8V1A6W4-1|A0A8V1A6W4_CHICK Isoform 1 of CAP-Gly domain containing linker protein 1 OS=Gallus gallus OX=9031 GN=CLIP1 PE=4 SV=1 CANONICAL=A0A8V1A6W4-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A1U8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6W4/entry#A0A8V1A1U8-1", "sequence": { "sequence": "MSMLKPSGLKAPSKTIKHGSTLLKAPASVATAPAEKAPSSEKSSSTTTADAHDDFVDDFRVGERVWVNGNKPGFIQFLGETQFAPGQWAGIVLDEPIGKNDGSVAGVRYFQCEPLRGIFTRPSKLSRKVLTEDEANGTQTAHASRATSPTSTSTASAVSASPAALLPSGIPQKTSPLAAKEHSTPSQFSNLSKTASGSVSNLSEAGSLKKGERELKIGDRVLVGGTKAGVVRFLGETDFAKGEWCGVELDEPLGKNDGAVAGTRYFQCQPRYGLFAPVHKVTKIGFPSTTPAKAKTTVRKVVATPAALKRSPSASSLSSLSSVASSVSSKPSRTGLLTETSSRYARKISGTTALQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALVRDGHDRHVLEMEAKMDQLRAMVEAADREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLEVATVSEKSRIMELERDLALRVKEVAELRGRLESSKHIDDVDTSLSLLQEISSLQEKMAAAGKEHQREMSSLKEKFESSEEALRKEIKTLSASNERMGKENESLKTKLDHANKENSDVIELWKSKLESAIASHQQAMEELKVSFNKGVGAQTAEFAELKTQMEKVKLDYENEMSNLKLKQENEKSQHLKEIEALKAKLLEVTEEKEQTLENLKAKLESVEDQHLVEMEDTLNKLQEAEIKVKELDVLQAKCNEQTKLIGSLTQQIRASEEKLLDLAALQKANSEGKLEIQKLSEQLQAAEKQIQNLETEKVGGSSKVSNLTKELQGKEQKLLDLEKNLSAVNQVKDSLEKELQLLKEKFTSAVDGAENAQRAMQETINKLNQKEEQFALMSSELEQLKSNLTVMETKLKEREEREQQLTEAKVKLENDIAEIMKSSGDSSAQLMKMNDELRLKERQLEQIQLELTKANEKAVQLQKNVEQTAQKAEQSQQETLKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKYEKETSEMITKHDADIKGFKQNLLDAEEALKAAQKKNDELETQAEELKKQAEQAKADKRAEEVLQTMEKVTKEKDAIHQEKIETLASLENSRQTNEKLQNELDMLKQNNLKNEEELTKSKELLNLENKKVEELKKEFEALKLAAAQKSQQLAALQEENVKLAEELGRSRDEVTSHQKLEEERSVLNNQLLEMKKRESTLKKEIDEERASLQKSISDTSALITQKDEELEKLRNEITVLRGENASAKTLQSVVKTLESDKLKLEEKVKNLEQKLKAKSEQPLTVTSPSGDIAANLLQDESAEDKQVFDLKHQQAKTAVCRVKSSQIQFLADFGNQDYDRQLFVFTFCF", "length": 1330, "header": "tr|A0A8V1A1U8-1|A0A8V1A6W4_CHICK Computationally mapped isoform of CAP-Gly domain containing linker protein 1 OS=Gallus gallus OX=9031 GN=CLIP1 PE=4 SV=1 CANONICAL=A0A8V1A6W4-1" }, "locus": { "chromosome": "15", "start_pos": 5883018, "end_pos": 5833209, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065559.1", "url": "https://www.ensembl.org/id/ENSGALT00010065559.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039857.1", "url": "https://www.ensembl.org/id/ENSGALP00010039857.1" } ] } }, { "isoform_ac": "A0A8V1A1V2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6W4/entry#A0A8V1A1V2-1", "sequence": { "sequence": "MSMLKPSGLKAPSKTIKHGSTLLKAPASVATAPAEKAPSSEKSSSTTTADAHDDFVDDFRVGERVWVNGNKPGFIQFLGETQFAPGQWAGIVLDEPIGKNDGSVAGVRYFQCEPLRGIFTRPSKLSRKVLTEDEANGTQTAHASRATSPTSTSTASAVSASPAALLPSGIPQKTSPLAAKEHSTPSQFSNLSKTASGSVSNLSEAGSLKKGERELKIGDRVLVGGTKAGVVRFLGETDFAKGEWCGVELDEPLGKNDGAVAGTRYFQCQPRYGLFAPVHKVTKIGFPSTTPAKAKTTVRKVVATPAALKRSPSASSLSSLSSVASSVSSKPSRTGLLTETSSRYARKISGTTALQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALVRDGHDRHVLEMEAKMDQLRAMVEAADREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLETQTKLEHARIKELEQSLLFEKTKADKLQRELEDTRVATVSEKSRIMELERDLALRVKEVAELRGRLESSKHIDDVDTSLSLLQEISSLQEKMAAAGKEHQREMSSLKEKFESSEEALRKEIKTLSASNERMGKENESLKTKLDHANKENSDVIELWKSKLESAIASHQQAMEELKVSFNKGVGAQTAEFAELKTQMEKVKLDYENEMSNLKLKQENEKSQHLKEIEALKAKLLEVTEEKEQTLENLKAKLESVEDQHLVEMEDTLNKLQEAEIKVKELDVLQAKCNEQTKLIGSLTQQIRASEEKLLDLAALQKANSEGKLEIQKLSEQLQAAEKQIQNLETEKVGGSSKVSNLTKELQGKEQKLLDLEKNLSAVNQVKDSLEKELQLLKEKFTSAVDGAENAQRAMQVMETKLKEREEREQQLTEAKVKLENDIAEIMKSSGDSSAQLMKMNDELRLKERQLEQIQLELTKANEKAVQLQKNVEQTAQKAEQSQQETLKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKYEKETSEMITKHDADIKGFKQNLLDAEEALKAAQKKNDELETQAEELKKQAEQAKADKRAEEVLQTMEKVTKEKDAIHQEKIETLASLENSRQTNEKLQNELDMLKQNNLKNEEELTKSKELLNLENKKVEELKKEFEALKLAAAQKSQQLAALQEENVKLAEELGRSRDEVTSHQKLEEERSVLNNQLLEMKKRESTLKKEIDEERASLQKSISDTSALITQKDEELEKLRNEITVLRGENASAKTLQSVVKTLESDKLKLEEKVKNLEQKLKAKSEQPLTVTSPSGDIAANLLQDESAEDKQIDFLNSVIVDLQRRNEELNLKIQRMCEAALNGNEEETINYDSEEEGLSKKTPRLFCDICGCFDLHDTEDCPTQAQMLEEPPHSTYHGSRREERPYCDTCEMFGHWTADCNDDETF", "length": 1409, "header": "tr|A0A8V1A1V2-1|A0A8V1A6W4_CHICK Computationally mapped isoform of CAP-Gly domain containing linker protein 1 OS=Gallus gallus OX=9031 GN=CLIP1 PE=4 SV=1 CANONICAL=A0A8V1A6W4-1" }, "locus": { "chromosome": "15", "start_pos": 5883018, "end_pos": 5831396, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065567.1", "url": "https://www.ensembl.org/id/ENSGALT00010065567.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039862.1", "url": "https://www.ensembl.org/id/ENSGALP00010039862.1" } ] } }, { "isoform_ac": "A0A8V1A6W4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6W4/entry#A0A8V1A6W4-1", "sequence": { "sequence": "MSMLKPSGLKAPSKTIKHGSTLLKAPASVATAPAEKAPSSEKSSSTTTADAHDDFVDDFRVGERVWVNGNKPGFIQFLGETQFAPGQWAGIVLDEPIGKNDGSVAGVRYFQCEPLRGIFTRPSKLSRKVLTEDEANGTQTAHASRATSPTSTSTASAVSASPAALLPSGIPQKTSPLAAKEHSTPSQFSNLSKTASGSVSNLSEAGSLKKGERELKIGDRVLVGGTKAGVVRFLGETDFAKGEWCGVELDEPLGKNDGAVAGTRYFQCQPRYGLFAPVHKVTKIGFPSTTPAKAKTTVRKVVATPAALKRSPSASSLSSLSSVASSVSSKPSRTGLLTETSSRYARKISGTTALQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALVRDGHDRHVLEMEAKMDQLRAMVEAADREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLERKRQISEDPENVATVSEKSRIMELERDLALRVKEVAELRGRLESSKHIDDVDTSLSLLQEISSLQEKMAAAGKEHQREMSSLKEKFESSEEALRKEIKTLSASNERMGKENESLKTKLDHANKENSDVIELWKSKLESAIASHQQAMEELKVSFNKGVGAQTAEFAELKTQMEKVKLDYENEMSNLKLKQENEKSQHLKEIEALKAKLLEVTEEKEQTLENLKAKLESVEDQHLVEMEDTLNKLQEAEIKVKELDVLQAKCNEQTKLIGSLTQQIRASEEKLLDLAALQKANSEGKLEIQKLSEQLQAAEKQIQNLETEKVGGSSKVSNLTKELQGKEQKLLDLEKNLSAVNQVKDSLEKELQLLKEKFTSAVDGAENAQRAMQETINKLNQKEEQFALMSSELEQLKSNLTVMETKLKEREEREQQLTEAKVKLENDIAEIMKSSGDSSAQLMKMNDELRLKERQLEQIQLELTKANEKAVQLQKNVEQTAQKAEQSQQETLKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKYEKETSEMITKHDADIKGFKQNLLDAEEALKAAQKKNDELETQAEELKKQAEQAKSLSSVLASARKEIELMSDKMRDLISEKETLAQERNTLKLEKESLLSQHLEMESKILLVQQDREELWTKNEELNSENKKILKQKEAAEAKSRQESTEKVALISEKSKLLSEIETAQADLLKITQENDALRSSESTLLQQLKELQANKDAVDVACQKHIKEREELEHYQKLLEENDRVIKDKDDVIQRLQSSYDDLARNQRELLQEVSILTAERDSAQEKDLDLKSTHIALKNEIDCLLQTNRSLQSEKEMLLKSREELCVSLANTANENQALKLRKDEMQTELETEREKLEKMTKDNMDLKASLSSLSNFLEEMKSSREASNSEKIHLLQEALFASEQRLLAEREELVNENKAVTEKLTKATADAVLAETAFTEKINELNLEKESVFSKSLQFEKHNEALLREKDELERKYSELLDEKKSLENAFSDMKREQELDFSAKRLLVQENTTLKYSIEALEEELKKKNLENQELIACRSDLSDLLKEAQDARRTLENELAAVSHAKQVLSSSFNTCSSDIEILNRERTELQDKCQKLTGEVENMKENLTVEKKARILDKESFLLERMELQNNIGFLEKEVEEMREKNKEFLTEKELLVQEKEKSETKLEEVIKEKMILYKETEQLASKIEQLKSDFTSLSVSKAELEDVHSCVSVMLDELQHKYEVTEKEKMELVQENESLHAEWKSLVIINEEILKEKEKLSKEYYKLHEKVVALLEQTDADFSCRLLVSEGKHELLLEEMSNLALKLREIERLQAQTFMQKFEADKRAEEVLQTMEKVTKEKDAIHQEKIETLASLENSRQTNEKLQNELDMLKQNNLKNEEELTKSKELLNLENKKVEELKKEFEALKLAAAQKSQQLAALQEENVKLAEELGRSRDEVTSHQKLEEERSVLNNQLLEMKKRESTLKKEIDEERASLQKSISDTSALITQKDEELEKLRNEITVLRGENASAKTLQSVVKTLESDKLKLEEKVKNLEQKLKAKSEQPLTVTSPSGDIAANLLQDESAEDKQQEIDFLNSVIVDLQRRNEELNLKIQRMCEAALNGNEEETINYDSEEEGLSKKTPRLFCDICGCFDLHDTEDCPTQAQMLEEPPHSTYHGSRREERPYCDTCEMFGHWTADCNDDETF", "length": 2175, "header": "tr|A0A8V1A6W4-1|A0A8V1A6W4_CHICK Isoform 1 of CAP-Gly domain containing linker protein 1 OS=Gallus gallus OX=9031 GN=CLIP1 PE=4 SV=1 CANONICAL=A0A8V1A6W4-1" }, "locus": { "chromosome": "15", "start_pos": 5883018, "end_pos": 5831396, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065564.1", "url": "https://www.ensembl.org/id/ENSGALT00010065564.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039859.1", "url": "https://www.ensembl.org/id/ENSGALP00010039859.1" } ] } }, { "isoform_ac": "A0A8V1A9E5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6W4/entry#A0A8V1A9E5-1", "sequence": { "sequence": "MSMLKPSGLKAPSKTIKHGSTLLKAPASVATAPAEKAPSSEKSSSTTTADAHDDFVDDFRVGERVWVNGNKPGFIQFLGETQFAPGQWAGIVLDEPIGKNDGSVAGVRYFQCEPLRGIFTRPSKLSRKVLTEDEANGTQTAHASRATSPTSTSTASAVSASPAALLPSGIPQKTSPLAAKEHSTPSQFSNLSKTASGSVSNLSEAGSLKKGERELKIGDRVLVGGTKAGVVRFLGETDFAKGEWCGVELDEPLGKNDGAVAGTRYFQCQPRYGLFAPVHKVTKIGFPSTTPAKAKTTVRKVVATPAALKRSPSASSLSSLSSVASSVSSKPSRTGLLTETSSRYARKISGTTALQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALVRDGHDRHVLEMEAKMDQLRAMVEAADREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLERKRQISEDPENVATVSEKSRIMELERDLALRVKEVAELRGRLESSKHIDDVDTSLSLLQEISSLQEKMAAAGKEHQREMSSLKEKFESSEEALRKEIKTLSASNERMGKENESLKTKLDHANKENSDVIELWKSKLESAIASHQQAMEELKVSFNKGVGAQTAEFAELKTQMEKVKLDYENEMSNLKLKQENEKSQHLKEIEALKAKLLEVTEEKEQTLENLKAKLESVEDQHLVEMEDTLNKLQEAEIKVKELDVLQAKCNEQTKLIGSLTQQIRASEEKLLDLAALQKANSEGKLEIQKLSEQLQAAEKQIQNLETEKVSNLTKELQGKEQKLLDLEKNLSAVNQVKDSLEKELQLLKEKFTSAVDGAENAQRAMQVMETKLKEREEREQQLTEAKVKLENDIAEIMKSSGDSSAQLMKMNDELRLKERQLEQIQLELTKANEKAVQLQKNVEQTAQKAEQSQQETLKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKYEKETSEMITKHDADIKGFKQNLLDAEEALKAAQKKNDELETQAEELKKQAEQAKSLSSVLASARKEIELMSDKMRDLISEKETLAQERNTLKLEKESLLSQHLEMESKILLVQQDREELWTKNEELNSENKKILKQKEAAEAKSRQESTEKVALISEKSKLLSEIETAQADLLKITQENDALRSSESTLLQQLKELQANKDAVDVACQKHIKEREELEHYQKLLEENDRVIKDKDDVIQRLQSSYDDLARNQRELLQEVSILTAERDSAQEKDLDLKSTHIALKNEIDCLLQTNRSLQSEKEMLLKSREELCVSLANTANENQALKLRKDEMQTELETEREKLEKMTKDNMDLKASLSSLSNFLEEMKSSREASNSEKIHLLQEALFASEQRLLAEREELVNENKAVTEKLTKATADAVLAETAFTEKINELNLEKESVFSKSLQFEKHNEALLREKDELERKYSELLDEKKSLENAFSDMKREQELDFSAKRLLVQENTTLKYSIEALEEELKKKNLENQELIACRSDLSDLLKEAQDARRTLENELAAVSHAKQVLSSSFNTCSSDIEILNRERTELQDKCQKLTGEVENMKENLTVEKKARILDKESFLLERMELQNNIGFLEKEVEEMREKNKEFLTEKELLVQEKEKSETKLEEVIKEKMILYKETEQLASKIEQLKSDFTSLSVSKAELEDVHSCVSVMLDELQHKYEVTEKEKMELVQENESLHAEWKSLVIINEEILKEKEKLSKEYYKLHEKVVALLEQTDADFSCRLLVSEGKHELLLEEMSNLALKLREIERLQAQTFMQKFEADKRAEEVLQTMEKVTKEKDAIHQEKIETLASLENSRQTNEKLQNELDMLKQNNLKNEEELTKSKELLNLENKKVEELKKEFEALKLAAAQKSQQLAALQEENVKLAEELGRSRDEVTSHQKLEEERSVLNNQLLEMKKRESTLKKEIDEERASLQKSISDTSALITQKDEELEKLRNEITVLRGENASAKTLQSVVKTLESDKLKLEEKVKNLEQKLKAKSEQPLTVTSPSGDIAANLLQDESAEDKQVFDLKHQQAKTAVCRVKSSQIQFLADFGNQDYDRQLFVFTFCF", "length": 2067, "header": "tr|A0A8V1A9E5-1|A0A8V1A9E5_CHICK Computationally mapped isoform of CAP-Gly domain containing linker protein 1 OS=Gallus gallus OX=9031 GN=CLIP1 PE=4 SV=1 CANONICAL=A0A8V1A6W4-1" }, "locus": { "chromosome": "15", "start_pos": 5883018, "end_pos": 5833209, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065549.1", "url": "https://www.ensembl.org/id/ENSGALT00010065549.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039851.1", "url": "https://www.ensembl.org/id/ENSGALP00010039851.1" } ] } }, { "isoform_ac": "A0A8V1ACA5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6W4/entry#A0A8V1ACA5-1", "sequence": { "sequence": "MSMLKPSGLKAPSKTIKHGSTLLKAPASVATAPAEKAPSSEKSSSTTTADAHDDFVDDFRVGERVWVNGNKPGFIQFLGETQFAPGQWAGIVLDEPIGKNDGSVAGVRYFQCEPLRGIFTRPSKLSRKVLTEDEANGTQTAHASRATSPTSTSTASAVSASPAALLPSGIPQKTSPLAAKEHSTPSQFSNLSKTASGSVSNLSEAGSLKKGERELKIGDRVLVGGTKAGVVRFLGETDFAKGEWCGVELDEPLGKNDGAVAGTRYFQCQPRYGLFAPVHKVTKIGFPSTTPAKAKTTVRKVVATPAALKRSPSASSLSSLSSVASSVSSKPSRTGLLTETSSRYARKISGTTALQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALVRDGHDRHVLEMEAKMDQLRAMVEAADREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLETQTKLEHARIKELEQSLLFEKTKADKLQRELEDTRVATVSEKSRIMELERDLALRVKEVAELRGRLESSKHIDDVDTSLSLLQEISSLQEKMAAAGKEHQREMSSLKEKFESSEEALRKEIKTLSASNERMGKENESLKTKLDHANKENSDVIELWKSKLESAIASHQQAMEELKVSFNKGVGAQTAEFAELKTQMEKVKLDYENEMSNLKLKQENEKSQHLKEIEALKAKLLEVTEEKEQTLENLKAKLESVEDQHLVEMEDTLNKLQEAEIKVKELDVLQAKCNEQTKLIGSLTQQIRASEEKLLDLAALQKANSEGKLEIQKLSEQLQAAEKQIQNLETEKVGGSSKVSNLTKELQGKEQKLLDLEKNLSAVNQVKDSLEKELQLLKEKFTSAVDGAENAQRAMQETINKLNQKEEQFALMSSELEQLKSNLTVMETKLKEREEREQQLTEAKVKLENDIAEIMKSSGDSSAQLMKMNDELRLKERQLEQIQLELTKANEKAVQLQKNVEQTAQKAEQSQQETLKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKYEKETSEMITKHDADIKGFKQNLLDAEEALKAAQKKNDELETQAEELKKQAEQAKADKRAEEVLQTMEKVTKEKDAIHQEKIETLASLENSRQTNEKLQNELDMLKQNNLKNEEELTKSKELLNLENKKVEELKKEFEALKLAAAQKSQQLAALQEENVKLAEELGRSRDEVTSHQKLEEERSVLNNQLLEMKKRESTLKKEIDEERASLQKSISDTSALITQKDEELEKLRNEITVLRGENASAKTLQSVVKTLESDKLKLEEKVKNLEQKLKAKSEQPLTVTSPSGDIAANLLQDESAEDKQVFDLKHQQAKTAVCRVKSSQIQFLADFGNQDYDRQLFVFTFCF", "length": 1365, "header": "tr|A0A8V1ACA5-1|A0A8V1ACA5_CHICK Computationally mapped isoform of CAP-Gly domain containing linker protein 1 OS=Gallus gallus OX=9031 GN=CLIP1 PE=4 SV=1 CANONICAL=A0A8V1A6W4-1" }, "locus": { "chromosome": "15", "start_pos": 5883018, "end_pos": 5833209, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065555.1", "url": "https://www.ensembl.org/id/ENSGALT00010065555.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039855.1", "url": "https://www.ensembl.org/id/ENSGALP00010039855.1" } ] } }, { "isoform_ac": "A0A8V1ACB1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6W4/entry#A0A8V1ACB1-1", "sequence": { "sequence": "MSMLKPSGLKAPSKTIKHGSTLLKAPASVATAPAEKAPSSEKSSSTTTADAHDDFVDDFRVGERVWVNGNKPGFIQFLGETQFAPGQWAGIVLDEPIGKNDGSVAGVRYFQCEPLRGIFTRPSKLSRKVLTEDEANGTQTAHASRATSPTSTSTASAVSASPAALLPSGIPQKTSPLAAKEHSTPSQFSNLSKTASGSVSNLSEAGSLKKGERELKIGDRVLVGGTKAGVVRFLGETDFAKGEWCGVELDEPLGKNDGAVAGTRYFQCQPRYGLFAPVHKVTKIGFPSTTPAKAKTTVRKVVATPAALKRSPSASSLSSLSSVASSVSSKPSRTGLLTETSSRYARKISGTTALQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALVRDGHDRHVLEMEAKMDQLRAMVEAADREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLETQTKLEHARIKELEQSLLFEKTKADKLQRELEDTRVATVSEKSRIMELERDLALRVKEVAELRGRLESSKHIDDVDTSLSLLQEISSLQEKMAAAGKEHQREMSSLKEKFESSEEALRKEIKTLSASNERMGKENESLKTKLDHANKENSDVIELWKSKLESAIASHQQAMEELKVSFNKGVGAQTAEFAELKTQMEKVKLDYENEMSNLKLKQENEKSQHLKEIEALKAKLLEVTEEKEQTLENLKAKLESVEDQHLVEMEDTLNKLQEAEIKVKELDVLQAKCNEQTKLIGSLTQQIRASEEKLLDLAALQKANSEGKLEIQKLSEQLQAAEKQIQNLETEKVSNLTKELQGKEQKLLDLEKNLSAVNQVKDSLEKELQLLKEKFTSAVDGAENAQRAMQETINKLNQKEEQFALMSSELEQLKSNLTVMETKLKEREEREQQLTEAKVKLENDIAEIMKSSGDSSAQLMKMNDELRLKERQLEQIQLELTKANEKAVQLQKNVEQTAQKAEQSQQETLKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKYEKETSEMITKHDADIKGFKQNLLDAEEALKAAQKKNDELETQAEELKKQAEQAKADKRAEEVLQTMEKVTKEKDAIHQEKIETLASLENSRQTNEKLQNELDMLKQNNLKNEEELTKSKELLNLENKKVEELKKEFEALKLAAAQKSQQLAALQEENVKLAEELGRSRDEVTSHQKLEEERSVLNNQLLEMKKRESTLKKEIDEERASLQKSISDTSALITQKDEELEKLRNEITVLRGENASAKTLQSVVKTLESDKLKLEEKVKNLEQKLKAKSEQPLTVTSPSGKRENFFISLLDLQRRNEELNLKIQRMCEAALNGNEEETINYDSEEEGLSKKTPRLFCDICGCFDLHDTEDCPTQAQMLEEPPHSTYHGSRREERPYCDTCEMFGHWTADCNDDETF", "length": 1416, "header": "tr|A0A8V1ACB1-1|A0A8V1ACB1_CHICK Computationally mapped isoform of CAP-Gly domain containing linker protein 1 OS=Gallus gallus OX=9031 GN=CLIP1 PE=4 SV=1 CANONICAL=A0A8V1A6W4-1" }, "locus": { "chromosome": "15", "start_pos": 5883018, "end_pos": 5831396, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065565.1", "url": "https://www.ensembl.org/id/ENSGALT00010065565.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039860.1", "url": "https://www.ensembl.org/id/ENSGALP00010039860.1" } ] } }, { "isoform_ac": "A0A8V1AEC0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6W4/entry#A0A8V1AEC0-1", "sequence": { "sequence": "MSMLKPSGLKAPSKTIKHGSTLLKAPASVATAPAEKAPSSEKSSSTTTADAHDDFVDDFRVGERVWVNGNKPGFIQFLGETQFAPGQWAGIVLDEPIGKNDGSVAGVRYFQCEPLRGIFTRPSKLSRKVLTEDEANGTQTAHASRATSPTSTSTASAVSASPAALLPSGIPQKTSPLAAKEHSTPSQFSNLSKTASGSVSNLSEAGSLKKGERELKIGDRVLVGGTKAGVVRFLGETDFAKGEWCGVELDEPLGKNDGAVAGTRYFQCQPRYGLFAPVHKVTKIGFPSTTPAKAKTTVRKVVATPAALKRSPSASSLSSLSSVASSVSSKPSRTGLLTETSSRYARKISGTTALQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALVRDGHDRHVLEMEAKMDQLRAMVEAADREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLERKRQISEDPENTQTKLEHARIKELEQSLLFEKTKADKLQRELEDTRVATVSEKSRIMELERDLALRVKEVAELRGRLESSKHIDDVDTSLSLLQEISSLQEKMAAAGKEHQREMSSLKEKFESSEEALRKEIKTLSASNERMGKENESLKTKLDHANKENSDVIELWKSKLESAIASHQQAMEELKVSFNKGVGAQTAEFAELKTQMEKVKLDYENEMSNLKLKQENEKSQHLKEIEALKAKLLEVTEEKEQTLENLKAKLESVEDQHLVEMEDTLNKLQEAEIKVKELDVLQAKCNEQTKLIGSLTQQIRASEEKLLDLAALQKANSEGKLEIQKLSEQLQAAEKQIQNLETEKVSNLTKELQGKEQKLLDLEKNLSAVNQVKDSLEKELQLLKEKFTSAVDGAENAQRAMQETINKLNQKEEQFALMSSELEQLKSNLTVMETKLKEREEREQQLTEAKVKLENDIAEIMKSSGDSSAQLMKMNDELRLKERQLEQIQLELTKANEKAVQLQKNVEQTAQKAEQSQQETLKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKYEKETSEMITKHDADIKGFKQNLLDAEEALKAAQKKNDELETQAEELKKQAEQAKSLSSVLASARKEIELMSDKMRDLISEKETLAQERNTLKLEKESLLSQHLEMESKILLVQQDREELWTKNEELNSENKKILKQKEAAEAKSRQESTEKVALISEKSKLLSEIETAQADLLKITQENDALRSSESTLLQQLKELQANKDAVDVACQKHIKEREELEHYQKLLEENDRVIKDKDDVIQRLQSSYDDLARNQRELLQEVSILTAERDSAQEKDLDLKSTHIALKNEIDCLLQTNRSLQSEKEMLLKSREELCVSLANTANENQALKLRKDEMQTELETEREKLEKMTKDNMDLKASLSSLSNFLEEMKSSREASNSEKIHLLQEALFASEQRLLAEREELVNENKAVTEKLTKATADAVLAETAFTEKINELNLEKESVFSKSLQFEKHNEALLREKDELERKYSELLDEKKSLENAFSDMKREQELDFSAKRLLVQENTTLKYSIEALEEELKKKNLENQELIACRSDLSDLLKEAQDARRTLENELAAVSHAKQVLSSSFNTCSSDIEILNRERTELQDKCQKLTGEVENMKENLTVEKKARILDKESFLLERMELQNNIGFLEKEVEEMREKNKEFLTEKELLVQEKEKSETKLEEVIKEKMILYKETEQLASKIEQLKSDFTSLSVSKAELEDVHSCVSVMLDELQHKYEVTEKEKMELVQENESLHAEWKSLVIINEEILKEKEKLSKEYYKLHEKVVALLEQTDADFSCRLLVSEGKHELLLEEMSNLALKLREIERLQAQTFMQKFEADKRAEEVLQTMEKVTKEKDAIHQEKIETLASLENSRQTNEKLQNELDMLKQNNLKNEEELTKSKELLNLENKKVEELKKEFEALKLAAAQKSQQLAALQEENVKLAEELGRSRDEVTSHQKLEEERSVLNNQLLEMKKRESTLKKEIDEERASLQKSISDTSALITQKDEELEKLRNEITVLRGENASAKTLQSVVKTLESDKLKLEEKVKNLEQKLKAKSEQPLTVTSPSGDIAANLLQDESAEDKQVFDLKHQQAKTAVCRVKSSQIQFLADFGNQDYDRQLFVFTFCF", "length": 2130, "header": "tr|A0A8V1AEC0-1|A0A8V1AEC0_CHICK Computationally mapped isoform of CAP-Gly domain containing linker protein 1 OS=Gallus gallus OX=9031 GN=CLIP1 PE=4 SV=1 CANONICAL=A0A8V1A6W4-1" }, "locus": { "chromosome": "15", "start_pos": 5883018, "end_pos": 5833209, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065552.1", "url": "https://www.ensembl.org/id/ENSGALT00010065552.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039853.1", "url": "https://www.ensembl.org/id/ENSGALP00010039853.1" } ] } }, { "isoform_ac": "A0A8V1AED1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6W4/entry#A0A8V1AED1-1", "sequence": { "sequence": 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"url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A6W4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6W4" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A6W4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6W4" } ], "pmid": "" }, { "name": "cell cortex", "id": "GO:0005938", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005938", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A6W4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6W4" } ], "pmid": "" }, { "name": "microtubule plus-end", "id": "GO:0035371", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035371", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A6W4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6W4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "microtubule plus-end 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"http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22881", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22881:SF12", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22881:SF12", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00439", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00439", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00855", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00855", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF10513", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10513", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13831", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13831", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13832", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13832", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1A1X2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1X2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A1X2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1X2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A9H5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9H5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A9H5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9H5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A9I1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9I1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A9I1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9I1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ACD4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACD4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ACD4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACD4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPMMTVAQIPSYRLNKICSGISLQRKNQFMQRLHNYWLLKRQARNGVPLIRRLHSHLQSQRNAEQKEQDEKTSAVKEELKYWQKLRHDLERARLLIELIRKREKLKREQVKVQQAAMELWLTPFNVLLRTTLDLLQEKDAAQIFAEPVNLNEVPDYLEFISNPMDFSTMRRKLESHLYRTLDEFEEDFNLIVTNCMRYNAKDTIFHRAAVRLRDLGGAILRHVRRQAESIGFDTDVGIHLPESPKTEDFYRFSWEDVDNILLPENRAHLSLEAQLKELLEKLDIVSPMRSSGARTRRMRLLRREINSVRQKLAQQQSRTMANGEPVLWEEELDKTSREEDEEGDDAKLPHPPTLEPTGPAPSFSELESLQDPPKLKPIHDSKSLNQLQKKVMSDRDFFDKKALQRESQAFQRLLSDSSLNGLTLPPADTLMSPPFSGVGRRTSVLFKKAKNGVKLQKGLDCSLENGEDHEQSEQLSPSCANGERQTRKRPQSRNYSESDGEKSPRQAGQRGVTNGFAKHAESGSDSEHSPSLGSGLVFETCSGLMPPKRSRGKPALSRVPFLEGVNGDSDYSSSGRTLLMSFESQTELEPLELVWAKCRGYPSYPALIIDPKMPREGLLHNGVPIPVPPMDVLKLGEQRQTEAGEKLFLVLFFDNKRTWQWLPRDKVYPLGVDDTVDKLKMMEGRKTSIRKSVQRELSPPAAAQLTQTGLCRHGAAVKTNKGLQNLERRDHTLPPTSPVGVT", "length": 742, "header": "tr|A0A8V1A9I1-1|A0A8V1A9I1_CHICK Isoform 1 of Bromodomain and PHD finger containing 3 OS=Gallus gallus OX=9031 GN=BRPF3 PE=4 SV=1 CANONICAL=A0A8V1A9I1-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A1X2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9I1/entry#A0A8V1A1X2-1", "sequence": { "sequence": "MGKVISIAGMRRLKFCEDRCLTAHTFSFVIIDPKMPREGLLHNGVPIPVPPMDVLKLGEQRQTEAGEKLFLVLFFDNKRTWQWLPRDKVYPLGVDDTVDKLKMMEGRKTSIRKSVQVAYDRAMIHMSRVRGDHPFVPSSYL", "length": 141, "header": "tr|A0A8V1A1X2-1|A0A8V1A9I1_CHICK Computationally mapped isoform of Bromodomain and PHD finger containing 3 OS=Gallus gallus OX=9031 GN=BRPF3 PE=4 SV=1 CANONICAL=A0A8V1A9I1-1" }, "locus": { "chromosome": "26", "start_pos": 250350, "end_pos": 247229, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065617.1", "url": "https://www.ensembl.org/id/ENSGALT00010065617.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039883.1", "url": "https://www.ensembl.org/id/ENSGALP00010039883.1" } ] } }, { "isoform_ac": "A0A8V1A9H5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9I1/entry#A0A8V1A9H5-1", "sequence": { "sequence": "MIIDPKMPREGLLHNGVPIPVPPMDVLKLGEQRQTEAGEKLFLVLFFDNKRTWQWLPRDKVYPLGVDDTVDKLKMMEGRKTSIRKSVQVAYDRAMIHMSRVRGDHPFVPSSYL", "length": 113, "header": "tr|A0A8V1A9H5-1|A0A8V1A9H5_CHICK Computationally mapped isoform of Bromodomain and PHD finger containing 3 OS=Gallus gallus OX=9031 GN=BRPF3 PE=4 SV=1 CANONICAL=A0A8V1A9I1-1" }, "locus": { "chromosome": "26", "start_pos": 250350, "end_pos": 248085, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065616.1", "url": "https://www.ensembl.org/id/ENSGALT00010065616.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039882.1", "url": "https://www.ensembl.org/id/ENSGALP00010039882.1" } ] } }, { "isoform_ac": "A0A8V1A9I1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9I1/entry#A0A8V1A9I1-1", "sequence": { "sequence": "MPMMTVAQIPSYRLNKICSGISLQRKNQFMQRLHNYWLLKRQARNGVPLIRRLHSHLQSQRNAEQKEQDEKTSAVKEELKYWQKLRHDLERARLLIELIRKREKLKREQVKVQQAAMELWLTPFNVLLRTTLDLLQEKDAAQIFAEPVNLNEVPDYLEFISNPMDFSTMRRKLESHLYRTLDEFEEDFNLIVTNCMRYNAKDTIFHRAAVRLRDLGGAILRHVRRQAESIGFDTDVGIHLPESPKTEDFYRFSWEDVDNILLPENRAHLSLEAQLKELLEKLDIVSPMRSSGARTRRMRLLRREINSVRQKLAQQQSRTMANGEPVLWEEELDKTSREEDEEGDDAKLPHPPTLEPTGPAPSFSELESLQDPPKLKPIHDSKSLNQLQKKVMSDRDFFDKKALQRESQAFQRLLSDSSLNGLTLPPADTLMSPPFSGVGRRTSVLFKKAKNGVKLQKGLDCSLENGEDHEQSEQLSPSCANGERQTRKRPQSRNYSESDGEKSPRQAGQRGVTNGFAKHAESGSDSEHSPSLGSGLVFETCSGLMPPKRSRGKPALSRVPFLEGVNGDSDYSSSGRTLLMSFESQTELEPLELVWAKCRGYPSYPALIIDPKMPREGLLHNGVPIPVPPMDVLKLGEQRQTEAGEKLFLVLFFDNKRTWQWLPRDKVYPLGVDDTVDKLKMMEGRKTSIRKSVQRELSPPAAAQLTQTGLCRHGAAVKTNKGLQNLERRDHTLPPTSPVGVT", "length": 742, "header": "tr|A0A8V1A9I1-1|A0A8V1A9I1_CHICK Isoform 1 of Bromodomain and PHD finger containing 3 OS=Gallus gallus OX=9031 GN=BRPF3 PE=4 SV=1 CANONICAL=A0A8V1A9I1-1" }, "locus": { "chromosome": "26", "start_pos": 253012, "end_pos": 236193, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065621.1", "url": "https://www.ensembl.org/id/ENSGALT00010065621.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039887.1", "url": "https://www.ensembl.org/id/ENSGALP00010039887.1" } ] } }, { "isoform_ac": "A0A8V1ACD4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9I1/entry#A0A8V1ACD4-1", "sequence": { "sequence": "MRKPRRRSRQKLEGRRSPSPYSLKCSPTRETLTYAQAQRIVEVDIDGRLHRISIYDPLKIITEDELTAQDITECNSNKENSEQPLFPSKSKKTPSKGKKREACSKHTSGTSLHLPQPNFRVVDSFKQSDAPPLPTAYYRYIEKPPEDLDAEVEYDMDEEDLAWLEMVNEKRRDDGYGMVSAETFELLVDRLEKESYLESRNNGTQHSIIDEDAFCCVCMDDECHNSNVILFCDICNLAVHQECYGVPYIPEGQWLCRCCLQSPSRPVDCVLCPNKGGAFKQTSDGRWAHVVCAIWIPEVCFANTVFLEPIEGINNIPPARWKLTCYICKQKGMGAAIQCHKVNCYTAFHVTCAQRAGLFMKIEPMRETSINGTTFTVRKTAYCESHSPPGTVKKTGIVKEEREEEGSSGPPKGSLKKNQVKLKQKIKKEPSEGTDGRSSMPMMTVAQIPSYRLNKICSGISLQRKNQFMQRLHNYWLLKRQARNGVPLIRRLHSHLQSQRNAEQKEQDEKTSAVKEELKYWQKLRHDLERARLLIELIRKREKLKREQVKVQQAAMELWLTPFNVLLRTTLDLLQEKDAAQIFAEPVNLNEVLYV", "length": 595, "header": "tr|A0A8V1ACD4-1|A0A8V1ACD4_CHICK Computationally mapped isoform of Bromodomain and PHD finger containing 3 OS=Gallus gallus OX=9031 GN=BRPF3 PE=4 SV=1 CANONICAL=A0A8V1A9I1-1" }, "locus": { "chromosome": "26", "start_pos": 240538, "end_pos": 234845, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065620.1", "url": "https://www.ensembl.org/id/ENSGALT00010065620.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039886.1", "url": "https://www.ensembl.org/id/ENSGALP00010039886.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "histone H4K12 acetyltransferase activity", "id": "GO:0043997", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043997", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9I1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9I1" } ], "pmid": "" }, { "name": "histone H4K5 acetyltransferase activity", "id": "GO:0043995", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043995", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9I1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9I1" } ], "pmid": "" }, { "name": "histone H4K8 acetyltransferase activity", "id": "GO:0043996", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043996", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9I1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9I1" } ], "pmid": "" }, { "name": "histone H3K14 acetyltransferase activity", "id": "GO:0036408", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036408", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9I1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9I1" } ], "pmid": "" }, { "name": "histone reader activity", "id": "GO:0140566", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140566", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9I1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9I1" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9I1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9I1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9I1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9I1" } ], "pmid": "" }, { "name": "MOZ/MORF histone acetyltransferase complex", "id": "GO:0070776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070776", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9I1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9I1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9I1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9I1" } ], "pmid": "" }, { "name": "positive regulation of DNA replication", "id": "GO:0045740", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045740", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9I1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9I1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 494, "end_pos": 496, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1A9I1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9I1" }, { "id": "PS50014", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50014" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Bromo", "eco_id": "ECO_0000259", "start_pos": 136, "end_pos": 206, "start_aa": "Gln", "end_aa": "His", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1A9I1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9I1" }, { "id": "PS50812", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50812" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PWWP", "eco_id": "ECO_0000259", "start_pos": 590, "end_pos": 673, "start_aa": "Pro", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 494, "end_pos": 496 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A772-1", "uniprot_ac": "A0A8V1A772", "uniprot_id": "A0A8V1A772_CHICK", "mass": { "chemical_mass": 143205.0, "monoisotopic_mass": 143205.0 }, "refseq": {}, "gene_names": [ { "name": "PPFIA1", "type": "recommended", "evidence": [ { "id": "A0A8V1A772", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A772" } ] } ], "protein_names": [ { "name": "PTPRF interacting protein alpha 1", "type": "synonym", "evidence": [ { "id": "A0A8V1A772", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A772/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A772", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A772" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PPFIA1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A772", "locus": { "chromosome": "5", "start_pos": 17441298, "end_pos": 17393213, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010024757", "url": "https://www.ensembl.org/id/ENSGALG00010024757" } ] } } ], "crossref": [ { "id": "A0A8V1A772", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A772", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd09562", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09562", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd09565", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09565", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd09568", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09568", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "423147", "url": "https://www.ncbi.nlm.nih.gov/gene/423147", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001660", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001660", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013761", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013761", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029515", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029515", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037620", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037620", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037621", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037621", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037622", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037622", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057892", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057892", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZUI4", "url": "https://www.orthodb.org/?gene=A0A8V0ZUI4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A1Z4", "url": "https://www.orthodb.org/?gene=A0A8V1A1Z4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A772", "url": "https://www.orthodb.org/?gene=A0A8V1A772", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A780", "url": "https://www.orthodb.org/?gene=A0A8V1A780", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12587", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12587", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12587:SF15", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12587:SF15", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00536", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00536", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07647", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07647", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25526", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25526", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-181429", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-181429", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-181430", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-181430", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-212676", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-212676", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-264642", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-264642", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-388844", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-388844", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZUI4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUI4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZUI4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUI4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A1Z4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1Z4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A1Z4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1Z4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A772", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A772", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A772-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A772-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A780", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A780", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A780-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A780-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMCEVMPTISEAEIPSGGNGGHGSGSPLQSDADSHFEQLMVSMLEERDRLLETLRETQETLALTQGKLHEVGHERDSLQRQLNTALPQEFAALTKELNVCREQLLEREEEIAELKAERNNTRLLLEHLECLVSRHERSLRMTVVKRQAQSPAGVSSEVEVLKALKSLFEHHKALDEKVRERLRVALERCSLLEEELGTTHKELMILKEQNNQKKTLPDGMLDINHEQESTPTTNGKRSSDGSLCHDENLAKVIELQDIIDKQNKEQTQMKERLTALSSRVAELEEDLDTARKDLIKSEEMNTKLQRDVRETMAQKEDMEERITTLEKRYLAAQREATSVHDLNDKLENEIATKDSMHRQSEDKNRQLQERLELAEQKLQQTLRKAETLPEVEAELAQRVAALSKSDLLSSGNSAAKDAKVLELTTKLRKAEERHGNIEERLRQMEAQLEEKNQELQRARQREKMNEEHNKRLSETVDKLLSESNERLQLHLKERMAALEDKNSLLREIENAKKQIEELQHEKDKLLLNIEALRAENDQVRLRATSLHHSRPDFRYPMAPSSVADSHADSYGTSVLRRPQKGRLAALRDEPSKVQTLNEQDWERAQQASVLANVAQAFESDVDVSDGEDDRETIFSSVDLLSPSGQADAQTLAMMLQEQLDAINKEIRLIQEEKENTEQRAEEIESRVGSGSLDAHGRFRSMSSIPPPYASGSLAGSSPPGSGRSTPRRIPHSPAREVDRLGIMTLPSDLRKHRRKSPSSREEVRDDKATIKCETSPPSSPRSLRLDRVQKGALHTVSHEDIRDIRNSTGSQDGQASNPSSSNSSQDSLHKAPKKKGIKSSIGRLFGKKEKGRPGQTSKEALGQVGVAEADSSSQDALGLSKLGGQAEKNRKMQKKHELLEEARRQGLPFAQWDGPTVVVWLELWVGMPAWYVAACRANVKSGAIMSALSDTEIQREIGISNPLHRLKLRLAIQEIMSLTSPSAPPTSRTTTGNVWVTHEEMENLTASQQTEDEEGSWAQTLAYGDMNHEWIGNEWLPSLGLPQYRSYFMECLVDARMLDHLTKKDLRGQLKMVDSFHRNSFQCGIMCLRRLNYDRKELERKREESQSEIKDVLVWSNERMIHWVLSIGLKEYANNLLESGVHGALVALDETFDYNALALLLQIPTQNTQARAVLEREFNNLLVMGTDRRLDEDDDKSFRRAPSWRKKFRPKDIRGLAAGSAETLPANFRVTTSMSSPSMQPKKMQIDGSVSGTQRLDSATVRTYSC", "length": 1266, "header": "tr|A0A8V1A772-1|A0A8V1A772_CHICK Isoform 1 of PTPRF interacting protein alpha 1 OS=Gallus gallus OX=9031 GN=PPFIA1 PE=1 SV=1 CANONICAL=A0A8V1A772-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZUI4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A772/entry#A0A8V0ZUI4-1", "sequence": { "sequence": "MMCEVMPTISEAEIPSGGNGGHGSGSPLQSDADSHFEQLMVSMLEERDRLLETLRETQETLALTQGKLHEVGHERDSLQRQLNTALPQEFAALTKELNVCREQLLEREEEIAELKAERNNTRLLLEHLECLVSRHERSLRMTVVKRQAQSPAGVSSEVEVLKALKSLFEHHKALDEKVRERLRVALERCSLLEEELGTTHKELMILKEQNNQKKTLPDGMLDINHEQESTPTTNGKRSSDGSLCHDENLAKVIELQDIIDKQNKEQTQMKERLTALSSRVAELEEDLDTARKDLIKSEEMNTKLQRDVRETMAQKEDMEERITTLEKRYLAAQREATSVHDLNDKLENEIATKDSMHRQSEDKNRQLQERLELAEQKLQQTLRKAETLPEVEAELAQRVAALSKAEERHGNIEERLRQMEAQLEEKNQELQRARQREKMNEEHNKRLSETVDKLLSESNERLQLHLKERMAALEDKNSLLREIENAKKQIEELQHEKDKLLLNIEALRAENDQVRLRATSLHHSRPDFRYPMAPSSVADSHADSYGTSVLRRPQKGRLAALRDEPSKVQTLNEQDWERAQQASVLANVAQAFESDVDVSDGEDDRETIFSSVDLLSPSGQADAQTLAMMLQEQLDAINKEIRLIQEEKENTEQRAEEIESRVGSGSLDAHGRFRSMSSIPPPYASGSLAGSSPPGSGRSTPRRIPHSPAREVDRLGIMTLSPSSREEVRDDKATIKCETSPPSSPRSLRLDRVQKGALHTVSHEDIRDIRNSTGSQDGQASNPSSSNSSQDSLHKAPKKKGIKSSIGRLFGKKEKGRPGQTSKEALGQVGVAEADSSSQDALGLSKLGGQAEKNRKMQKKHELLEEARRQGLPFAQWDGPTVVVWLELWVGMPAWYVAACRANVKSGAIMSALSDTEIQREIGISNPLHRLKLRLAIQEIMSLTSPSAPPTSRTEDEEGSWAQTLAYGDMNHEWIGNEWLPSLGLPQYRSYFMECLVDARMLDHLTKKDLRGQLKMVDSFHRNSFQCGIMCLRRLNYDRKELERKREESQSEIKDVLVWSNERMIHWVLSIGLKEYANNLLESGVHGALVALDETFDYNALALLLQIPTQNTQARAVLEREFNNLLVMGTDRRLDEDDDKSFRRAPSWRKKFRPKDIRGLAAGSAETLPANFRVTTSMSSPSMQPKKMQIDGSVSGTQRLDSATVRTYSC", "length": 1210, "header": "tr|A0A8V0ZUI4-1|A0A8V0ZUI4_CHICK Computationally mapped isoform of PTPRF interacting protein alpha 1 OS=Gallus gallus OX=9031 GN=PPFIA1 PE=1 SV=1 CANONICAL=A0A8V1A772-1" }, "locus": { "chromosome": "5", "start_pos": 17438926, "end_pos": 17393213, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010060437.1", "url": "https://www.ensembl.org/id/ENSGALT00010060437.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010037196.1", "url": "https://www.ensembl.org/id/ENSGALP00010037196.1" } ] } }, { "isoform_ac": "A0A8V1A1Z4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A772/entry#A0A8V1A1Z4-1", "sequence": { "sequence": "MMCEVMPTISEAEIPSGGNGGHGSGSPLQSDADSHFEQLMVSMLEERDRLLETLRETQETLALTQGKLHEVGHERDSLQRQLNTALPQEFAALTKELNVCREQLLEREEEIAELKAERNNTRLLLEHLECLVSRHERSLRMTVVKRQAQSPAGVSSEVEVLKALKSLFEHHKALDEKVRERLRVALERCSLLEEELGTTHKELMILKEQNNQKKTLPDGMLDINHEQESTPTTNGKRSSDGSLCHDENLAKVIELQDIIDKQNKEQTQMKERLTALSSRVAELEEDLDTARKDLIKSEEMNTKLQRDVRETMAQKEDMEERITTLEKRYLAAQREATSVHDLNDKLENEIATKDSMHRQSEDKNRQLQERLELAEQKLQQTLRKAETLPEVEAELAQRVAALSKAEERHGNIEERLRQMEAQLEEKNQELQRARQREKMNEEHNKRLSETVDKLLSESNERLQLHLKERMAALEDKNSLLREIENAKKQIEELQHEKDKLLLNIEALRAENDQVRLRATSLHHSRPDFRYPMAPSSVADSHADSYGTSVLRRPQKGRLAALRDEPSKVQTLNEQDWERAQQASVLANVAQAFESDVDVSDGEDDRETIFSSVDLLSPSGQADAQTLAMMLQEQLDAINKEIRLIQEEKENTEQRAEEIESRVGSGSLDAHGRFRSMSSIPPPYASGSLAGSSPPGSGRSTPRRIPHSPAREVDRLGIMTLSPSSREEVRDDKATIKCETSPPSSPRSLRLDRVQKGALHTVSHEDIRDIRNSTGSQDGQASNPSSSNSSQDSLHKAPKKKGIKSSIGRLFGKKEKGRPGQTSKEALGQVGVAEADSSSQDALGLSKLGGQAEKNRKMQKKHELLEEARRQGLPFAQWDGPTVVVWLELWVGMPAWYVAACRANVKSGAIMSALSDTEIQREIGISNPLHRLKLRLAIQEIMSLTSPSAPPTSRTTLAYGDMNHEWIGNEWLPSLGLPQYRSYFMECLVDARMLDHLTKKDLRGQLKMVDSFHRNSFQCGIMCLRRLNYDRKELERKREESQSEIKDVLVWSNERMIHWVLSIGLKEYANNLLESGVHGALVALDETFDYNALALLLQIPTQNTQARAVLEREFNNLLVMGTDRRLDEDDDKSFRRAPSWRKKFRPKDIRGLAAGSAETLPANFRVTTSMSSPSMQPKKMQIDVYPHYFYR", "length": 1190, "header": "tr|A0A8V1A1Z4-1|A0A8V1A772_CHICK Computationally mapped isoform of PTPRF interacting protein alpha 1 OS=Gallus gallus OX=9031 GN=PPFIA1 PE=1 SV=1 CANONICAL=A0A8V1A772-1" }, "locus": { "chromosome": "5", "start_pos": 17440294, "end_pos": 17393213, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010060446.1", "url": "https://www.ensembl.org/id/ENSGALT00010060446.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010037205.1", "url": "https://www.ensembl.org/id/ENSGALP00010037205.1" } ] } }, { "isoform_ac": "A0A8V1A772-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A772/entry#A0A8V1A772-1", "sequence": { "sequence": "MMCEVMPTISEAEIPSGGNGGHGSGSPLQSDADSHFEQLMVSMLEERDRLLETLRETQETLALTQGKLHEVGHERDSLQRQLNTALPQEFAALTKELNVCREQLLEREEEIAELKAERNNTRLLLEHLECLVSRHERSLRMTVVKRQAQSPAGVSSEVEVLKALKSLFEHHKALDEKVRERLRVALERCSLLEEELGTTHKELMILKEQNNQKKTLPDGMLDINHEQESTPTTNGKRSSDGSLCHDENLAKVIELQDIIDKQNKEQTQMKERLTALSSRVAELEEDLDTARKDLIKSEEMNTKLQRDVRETMAQKEDMEERITTLEKRYLAAQREATSVHDLNDKLENEIATKDSMHRQSEDKNRQLQERLELAEQKLQQTLRKAETLPEVEAELAQRVAALSKSDLLSSGNSAAKDAKVLELTTKLRKAEERHGNIEERLRQMEAQLEEKNQELQRARQREKMNEEHNKRLSETVDKLLSESNERLQLHLKERMAALEDKNSLLREIENAKKQIEELQHEKDKLLLNIEALRAENDQVRLRATSLHHSRPDFRYPMAPSSVADSHADSYGTSVLRRPQKGRLAALRDEPSKVQTLNEQDWERAQQASVLANVAQAFESDVDVSDGEDDRETIFSSVDLLSPSGQADAQTLAMMLQEQLDAINKEIRLIQEEKENTEQRAEEIESRVGSGSLDAHGRFRSMSSIPPPYASGSLAGSSPPGSGRSTPRRIPHSPAREVDRLGIMTLPSDLRKHRRKSPSSREEVRDDKATIKCETSPPSSPRSLRLDRVQKGALHTVSHEDIRDIRNSTGSQDGQASNPSSSNSSQDSLHKAPKKKGIKSSIGRLFGKKEKGRPGQTSKEALGQVGVAEADSSSQDALGLSKLGGQAEKNRKMQKKHELLEEARRQGLPFAQWDGPTVVVWLELWVGMPAWYVAACRANVKSGAIMSALSDTEIQREIGISNPLHRLKLRLAIQEIMSLTSPSAPPTSRTTTGNVWVTHEEMENLTASQQTEDEEGSWAQTLAYGDMNHEWIGNEWLPSLGLPQYRSYFMECLVDARMLDHLTKKDLRGQLKMVDSFHRNSFQCGIMCLRRLNYDRKELERKREESQSEIKDVLVWSNERMIHWVLSIGLKEYANNLLESGVHGALVALDETFDYNALALLLQIPTQNTQARAVLEREFNNLLVMGTDRRLDEDDDKSFRRAPSWRKKFRPKDIRGLAAGSAETLPANFRVTTSMSSPSMQPKKMQIDGSVSGTQRLDSATVRTYSC", "length": 1266, "header": "tr|A0A8V1A772-1|A0A8V1A772_CHICK Isoform 1 of PTPRF interacting protein alpha 1 OS=Gallus gallus OX=9031 GN=PPFIA1 PE=1 SV=1 CANONICAL=A0A8V1A772-1" }, "locus": { "chromosome": "5", "start_pos": 17438926, "end_pos": 17393213, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010060433.1", "url": "https://www.ensembl.org/id/ENSGALT00010060433.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010037192.1", "url": "https://www.ensembl.org/id/ENSGALP00010037192.1" } ] } }, { "isoform_ac": "A0A8V1A780-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A772/entry#A0A8V1A780-1", "sequence": { "sequence": "MMCEVMPTISEAEIPSGGNGGHGSGSPLQSDADSHFEQLMVSMLEERDRLLETLRETQETLALTQGKLHEVGHERDSLQRQLNTALPQEFAALTKELNVCREQLLEREEEIAELKAERNNTRLLLEHLECLVSRHERSLRMTVVKRQAQSPAGVSSEVEVLKALKSLFEHHKALDEKVRERLRVALERCSLLEEELGTTHKELMILKEQNNQKKTLPDGMLDINHEQESTPTTNGKRSSDGSLCHDENLAKVIELQDIIDKQNKEQTQMKERLTALSSRVAELEEDLDTARKDLIKSEEMNTKLQRDVRETMAQKEDMEERITTLEKRYLAAQREATSVHDLNDKLENEIATKDSMHRQSEDKNRQLQERLELAEQKLQQTLRKAETLPEVEAELAQRVAALSKAEERHGNIEERLRQMEAQLEEKNQELQRARQREKMNEEHNKRLSETVDKLLSESNERLQLHLKERMAALEDKNSLLREIENAKKQIEELQHEKDKLLLNIEALRAENDQVRLRATSLHHSRPDFRYPMAPSSVADSHADSYGTSVLRRPQKGRLAALRDEPSKVQTLNEQDWERAQQASVLANVAQAFESDVDVSDGEDDRETIFSSVDLLSPSGQADAQTLAMMLQEQLDAINKEIRLIQEEKENTEQRAEEIESRVGSGSLDAHGRFRSMSSIPPPYASGSLAGSSPPGSGRSTPRRIPHSPAREVDRLGIMTLSPSSREEVRDDKATIKCETSPPSSPRSLRLDRVQKGALHTVSHEDIRDIRNSTGSQDGQASNPSSSNSSQDSLHKAPKKKGIKSSIGRLFGKKEKGRPGQTSKEALGQVGVAEADSSSQDALGLSKLGGQAEKNRKMQKKHELLEEARRQGLPFAQWDGPTVVVWLELWVGMPAWYVAACRANVKSGAIMSALSDTEIQREIGISNPLHRLKLRLAIQEIMSLTSPSAPPTSRTTTGNVWVTHEEMENLTASQQTTLAYGDMNHEWIGNEWLPSLGLPQYRSYFMECLVDARMLDHLTKKDLRGQLKMVDSFHRNSFQCGIMCLRRLNYDRKELERKREESQSEIKDVLVWSNERMIHWVLSIGLKEYANNLLESGVHGALVALDETFDYNALALLLQIPTQNTQARAVLEREFNNLLVMGTDRRLDEDDDKSFRRAPSWRKKFRPKDIRGLAAGSAETLPANFRVTTSMSSPSMQPKKMQIDVYPHYFYR", "length": 1211, "header": "tr|A0A8V1A780-1|A0A8V1A780_CHICK Computationally mapped isoform of PTPRF interacting protein alpha 1 OS=Gallus gallus OX=9031 GN=PPFIA1 PE=1 SV=1 CANONICAL=A0A8V1A772-1" }, "locus": { "chromosome": "5", "start_pos": 17440294, "end_pos": 17393213, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010060443.1", "url": "https://www.ensembl.org/id/ENSGALT00010060443.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010037202.1", "url": "https://www.ensembl.org/id/ENSGALP00010037202.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-181429", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-181429", "resource": "Reactome", "description": "Serotonin Neurotransmitter Release Cycle" }, { "id": "R-GGA-181430", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-181430", "resource": "Reactome", "description": 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"o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A9Q2-1", "uniprot_ac": "A0A8V1A9Q2", "uniprot_id": "A0A8V1A9Q2_CHICK", "mass": { "chemical_mass": 94606.0, "monoisotopic_mass": 94606.0 }, "refseq": { "ac": "XP_040502074", "name": "sarcolemmal membrane-associated protein isoform X13", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040502074" }, "gene_names": [ { "name": "SLMAP", "type": "recommended", "evidence": [ { "id": "A0A8V1A9Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9Q2" } ] }, { "name": "SLMAP", "type": "synonym", "evidence": [ { "id": "XP_040502074", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040502074" } ] } ], "protein_names": [ { "name": "Sarcolemmal membrane-associated protein", "type": "recommended", "evidence": [ { "id": "A0A8V1A9Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9Q2/entry#names_and_taxonomy" } ] }, { "name": "sarcolemmal membrane-associated protein isoform X13", "type": "synonym", "evidence": [ { "id": "XP_040502074", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040502074" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052543.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040502074", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040502074" } ] }, { "annotation": "Associates with the striatin-interacting phosphatase and kinase (STRIPAK) core complex, forming the extended (SIKE1:SLMAP)STRIPAK complex. The (SIKE1:SLMAP)STRIPAK complex dephosphorylates STK3 leading to the inhibition of Hippo signaling and the control of cell growth. May play a role during myoblast fusion.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9Q2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9Q2#function" }, { "database": "UniProtKB", "id": "ARBA00057671", "url": "https://www.uniprot.org/uniprotkb/ARBA00057671#function" }, { "database": "UniProtKB", "id": "A0A8V1A244", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A244#function" }, { "database": "UniProtKB", "id": "A0A8V1A254", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A254#function" }, { "database": "UniProtKB", "id": "A0A8V1A261", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A261#function" }, { "database": "UniProtKB", "id": "A0A8V1A752", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A752#function" }, { "database": "UniProtKB", "id": "A0A8V1ACK5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK5#function" }, { "database": "UniProtKB", "id": "A0A8V1ACL0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACL0#function" }, { "database": "UniProtKB", "id": "A0A8V1AEL9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEL9#function" }, { "database": "UniProtKB", "id": "A0A8V1AEM4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEM4#function" }, { "database": "UniProtKB", "id": "A0A8V1AEM8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEM8#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9Q2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9Q2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SLMAP", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9Q2", "locus": { "chromosome": "12", "start_pos": 9016619, "end_pos": 8940521, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027093", "url": "https://www.ensembl.org/id/ENSGALG00010027093" } ] } } ], "crossref": [ { "id": "A0A8V1A9Q2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A9Q2", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd21911", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21911", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd22679", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22679", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "396360", "url": "https://www.ncbi.nlm.nih.gov/gene/396360", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000253", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000253", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008984", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008984", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051176", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051176", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR060659", "url": "https://www.ebi.ac.uk/interpro/entry/IPR060659", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR15715", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15715", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15715:SF22", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15715:SF22", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00498", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00498", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF27557", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27557", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF28341", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF28341", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040502074", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040502074", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1A244", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A244", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A244-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A244-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A254", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A254", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A254-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A254-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A261", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A261", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A261-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A261-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A752", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A752", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A752-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A752-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A9Q2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9Q2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A9Q2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9Q2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ACK5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ACK5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ACL0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACL0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ACL0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACL0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AEL9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEL9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AEL9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEL9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AEM4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEM4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AEM4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEM4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AEM8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEM8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AEM8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEM8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPSALAIFTCRPNSHPFQERHVYLDEPVKIGRSVARCRPAQNNATFDCKVLSRNHALVWFDHKTGKFYLQDTKSSNGTFINSQRLSRGSEESPPCEIMSGDIIQFGVDVTENTRKVTHGCIVSTIKLFLPDGMEARLRSDVIHAPLPSPVDKVAANTPSMYSQELFQLSQYLQEALHREQMLEQKLATLQRLLAVTQEASDTSWQALIDEDRLLSRLEVMGNQLQACSKNQTEDSIRKELIALQEDKHNYETTAKESLRRVLQEKIEVVRKLSEVERSLSNTEDECTHLKEMNERTQEELRELANKYNGAVNEIKDLSDKLKVAEGKQEEIQQKGLAEKKELQHKIDEMEEREQELQAKIEALQADNDFTNERLTALQVRLEHLQEKTLKEHNSLEHFLSKSGGDCTFIHQFIECQNKIIDEGHLTKVEETKLLKENQARVKESDLSDTLSPSKEKSSDDTTDAQMDDQDLNEPIAKVALLKDELQGAQSETEAKQEIQQLHKELIEAQELARTSKQKCFELQALLEEERRAYRVQVEESNKQINVLQAQLQRLQEDIENLREEKESEISSTRNELVSAQNEILSLQQVAEKAASERDTDISALQEELQTVRAELERWRKDASDYEKEIVSLQASFQLRCQQCEEQHKEEATRLKGELEKLKAEWSVLEAECVTLRKENTSLASELQRQEKELSSSQKQSLALTSNISVLEMSRKELEDQMGSLREKHQQDAASLKSQLSEAESQAKDVQKEYERTQTVLSELKAKYEMAEQEKQSITEELKQCKENLKLLQEKGNNPSILQPVPAVFIGLILAFLYWCYGPLW", "length": 824, "header": "tr|A0A8V1A9Q2-1|A0A8V1A9Q2_CHICK Isoform 1 of Sarcolemmal membrane-associated protein OS=Gallus gallus OX=9031 GN=SLMAP PE=1 SV=1 CANONICAL=A0A8V1A9Q2-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A244-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9Q2/entry#A0A8V1A244-1", "sequence": { "sequence": "MPSALAIFTCRPNSHPFQERHVYLDEPVKIGRSVARCRPAQNNATFDCKVLSRNHALVWFDHKTGKFYLQDTKSSNGTFINSQRLSRGSEESPPCEIMSGDIIQFGVDVTENTRKVTHGCIVSTIKLFLPDGMEARLRSDVIHAPLPSPVDKVAANTPSMYSQELFQLSQYLQEALHREQMLEQKLATLQRLLAVTQEASDTSWQALIDEDRLLSRLEVMGNQLQACSKNQTEDSIRKELIALQEDKHNYETTAKESLRRVLQEKIEVVRKLSEVERSLSNTEDECTHLKEMNERTQEELRELANKYNGAVNEIKDLSDKLKVAEGKQEEIQQKGLAEKKELQHKIDEMEEREQELQAKIEALQADNDFTNERLTALQGIQVDDFIPKINGSTEKDKIIDEGHLTKVEETKLLKENQARVKESDLSDTLSPSKEKSSDDTTDAQMDDQDLNEPIAKVALLKDELQGAQSETEAKQEIQQLHKELIEAQELARTSKQKCFELQALLEEERRAYRVQVEESNKQINVLQAQLQRLQEDIENLREEKESEISSTRNELVSAQNEILSLQQVAEKAASERDTDISALQEELQTVRAELERWRKDASDYEKEIVSLQASFQLRCQQCEEQHKEEATRLKGELEKLKAEWSVLEAECVTLRKENTSLASELQRQEKELSSSQKQSLALTSNISVLEMSRKELEDQMGSLREKHQQDAASLKSQLSEAESQAKDVQKEYERTQTVLSELKAKYEMAEQEKQSITEELKQCKENLKLLQEKGNNPSILQPVPAVFIGLILAFLYWCYGPLW", "length": 803, "header": "tr|A0A8V1A244-1|A0A8V1A9Q2_CHICK Computationally mapped isoform of Sarcolemmal membrane-associated protein OS=Gallus gallus OX=9031 GN=SLMAP PE=1 SV=1 CANONICAL=A0A8V1A9Q2-1" }, "locus": { "chromosome": "12", "start_pos": 9014839, "end_pos": 8941771, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065693.1", "url": "https://www.ensembl.org/id/ENSGALT00010065693.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039959.1", "url": "https://www.ensembl.org/id/ENSGALP00010039959.1" } ] } }, { "isoform_ac": "A0A8V1A254-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9Q2/entry#A0A8V1A254-1", "sequence": { "sequence": "MPSALAIFTCRPNSHPFQERHVYLDEPVKIGRSVARCRPAQNNATFDCKVLSRNHALVWFDHKTGKFYLQDTKSSNGTFINSQRLSRGSEESPPCEIMSGDIIQFGVDVTENTRKVTHGCIVSTIKLFLPDGMEARLRSDVIHAPLPSPVDKVAANTPSMYSQELFQLSQYLQEALHREQMLEQKLATLQRLLAVTQEASDTSWQALIDEDRLLSRLEVMGNQLQACSKNQTEDSIRKELIALQEDKHNYETTAKESLRRVLQEKIEVVRKLSEVERSLSNTEDECTHLKEMNERTQEELRELANKYNGAVNEIKDLSDKLKVAEGKQEEIQQKGLAEKKELQHKIDEMEEREQELQAKIEALQADNDFTNERLTALQVRLEHLQEKTLKEHNSLGIQVDDFIPKINGSTEKDKIIDEGHLTKVEETKLLKENQARVKESDLSDTLSPSKEKSSDDTTDAQMDDQDLNEPIAKVALLKDELQGAQSETEAKQEIQQLHKELIEAQELARTSKQKCFELQALLEEERRAYRVQVEESNKQINVLQAQLQRLQEDIENLREEKESEISSTRNELVSAQNEILSLQQVAEKAASERDTDISALQEELQTVRAELERWRKDASDYEKEIVSLQASFQLRCQQCEEQHKEEATRLKGELEKLKAEWSVLEAECVTLRKENTSLASELQRQEKELSSSQKQSLALTSNISVLEMSRKELEDQMGSLREKHQQDAASLKSQLSEAESQAKDVQKEYERTQTVLSELKAKYEMAEQEKQSITEELKQCKENLKLLQEKGNNPSILQPVPAVFIGLILAFLYWCYGPLW", "length": 820, "header": "tr|A0A8V1A254-1|A0A8V1A9Q2_CHICK Computationally mapped isoform of Sarcolemmal membrane-associated protein OS=Gallus gallus OX=9031 GN=SLMAP PE=1 SV=1 CANONICAL=A0A8V1A9Q2-1" }, "locus": { "chromosome": "12", "start_pos": 9014839, "end_pos": 8941771, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065703.1", "url": "https://www.ensembl.org/id/ENSGALT00010065703.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039969.1", "url": "https://www.ensembl.org/id/ENSGALP00010039969.1" } ] } }, { "isoform_ac": "A0A8V1A261-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9Q2/entry#A0A8V1A261-1", "sequence": { "sequence": "MPSALAIFTCRPNSHPFQERHVYLDEPVKIGRSVARCRPAQNNATFDCKVLSRNHALVWFDHKTGKFYLQDTKSSNGTFINSQRLSRGSEESPPCEIMSGDIIQFGVDVTENTRKVTHGCIVSTIKLFLPDGMEARLRSDVIHAPLPSPVDKVAANTPSMYSQELFQLSQYLQEALHREQMLEQKLATLQRLLAVTQEASDTSWQALIDEDRLLSRLEVMGNQLQACSKNQTEDSIRKELIALQEDKHNYETTAKESLRRVLQEKIEVVRKLSEVERSLSNTEDECTHLKEMNERTQEELRELANKYNGAVNEIKDLSDKLKVAEGKQEEIQQKGLAEKKELQHKIDEMEEREQELQAKIEALQADNDFTNERLTALQDKIIDEGHLTKVEETKLLKENQARVKESDLSDTLSPSKEKSSDDTTDAQMDDQDLNEPIAKVALLKDELQGAQSETEAKQEIQQLHKELIEAQELARTSKQKCFELQALLEEERRAYRVQVEESNKQINVLQAQLQRLQEDIENLREEKESEISSTRNELVSAQNEILSLQQVAEKAASERDTDISALQEELQTVRAELERWRKDASDYEKEIVSLQASFQLRCQQCEEQHKEEATRLKGELEKLKAEWSVLEAECVTLRKENTSLASELQRQEKELSSSQKQSLALTSNISVLEMSRKELEDQMGSLREKHQQDAASLKSQLSEAESQAKDVQKEYERTQTVLSELKAKYEMAEQEKQSITEELKQCKENLKLLQEKGNNPSILQPVPAVFIGLILAFLYWCYGPLW", "length": 786, "header": "tr|A0A8V1A261-1|A0A8V1A9Q2_CHICK Computationally mapped isoform of Sarcolemmal membrane-associated protein OS=Gallus gallus OX=9031 GN=SLMAP PE=1 SV=1 CANONICAL=A0A8V1A9Q2-1" }, "locus": { "chromosome": "12", "start_pos": 9014839, "end_pos": 8941771, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065708.1", "url": "https://www.ensembl.org/id/ENSGALT00010065708.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039974.1", "url": "https://www.ensembl.org/id/ENSGALP00010039974.1" } ] } }, { "isoform_ac": "A0A8V1A752-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9Q2/entry#A0A8V1A752-1", "sequence": { "sequence": "MPSALAIFTCRPNSHPFQERHVYLDEPVKIGRSVARCRPAQNNATFDCKVLSRNHALVWFDHKTGKFYLQDTKSSNGTFINSQRLSRGSEESPPCEIMSGDIIQFGVDVTENTRKVTHGCIVSTIKLFLPDGMEARLRSDVIHAPLPSPVDKVAANTPSMYSQELFQLSQYLQEALHREQMLEQKLATLQRLLAVTQEASDTSWQALIDEDRLLSRLEVMGNQLQACSKNQTEDSIRKELIALQEDKHNYETTAKESLRRVLQEKIEVVRKLSEVERSLSNTEDECTHLKEMNERTQEELRELANKYNGAVNEIKDLSDKLKVAEGKQEEIQQKGLAEKKELQHKIDEMEEREQELQAKIEALQADNDFTNERLTALQVRLEHLQEKTLKEHNSLGIQVDDFIPKINGSTEKDKIIDEGHLTKVEETKLLKENQARVKESDLSDTLSPSKEKSSDDTTDAQMDDQDLNEPIAKVALLKDELQGAQSETEAKQEIQQLHKELIEAQELARTSKQKCFELQALLEEERRAYRVQVEESNKQINVLQAQLQRLQEDIENLREEKESEISSTRNELVSAQNEILSLQQVAEKAASERDTDISALQEELQTVRAELERWRKDASDYEKEIVSLQASFQLRCQQCEEQHKEEATRLKGELEKLKAEWSVLEAECVTLRKENTSLASELQRQEKELSSSQKQSLALTSNISVLEMSRKELEDQMGSLREKHQQDAASLKSQLSEAESQAKDVQKEYERTQTVLSELKAKYEMAEQEKQSITEELKQCKENLKLLQEKGNNRQWPWMPVMAALVAVTAVVLYPGLTRASP", "length": 822, "header": "tr|A0A8V1A752-1|A0A8V1A752_CHICK Computationally mapped isoform of Sarcolemmal membrane-associated protein OS=Gallus gallus OX=9031 GN=SLMAP PE=1 SV=1 CANONICAL=A0A8V1A9Q2-1" }, "locus": { "chromosome": "12", "start_pos": 9015916, "end_pos": 8941771, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065695.1", "url": "https://www.ensembl.org/id/ENSGALT00010065695.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039961.1", "url": "https://www.ensembl.org/id/ENSGALP00010039961.1" } ] } }, { "isoform_ac": "A0A8V1A9Q2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9Q2/entry#A0A8V1A9Q2-1", "sequence": { "sequence": "MPSALAIFTCRPNSHPFQERHVYLDEPVKIGRSVARCRPAQNNATFDCKVLSRNHALVWFDHKTGKFYLQDTKSSNGTFINSQRLSRGSEESPPCEIMSGDIIQFGVDVTENTRKVTHGCIVSTIKLFLPDGMEARLRSDVIHAPLPSPVDKVAANTPSMYSQELFQLSQYLQEALHREQMLEQKLATLQRLLAVTQEASDTSWQALIDEDRLLSRLEVMGNQLQACSKNQTEDSIRKELIALQEDKHNYETTAKESLRRVLQEKIEVVRKLSEVERSLSNTEDECTHLKEMNERTQEELRELANKYNGAVNEIKDLSDKLKVAEGKQEEIQQKGLAEKKELQHKIDEMEEREQELQAKIEALQADNDFTNERLTALQVRLEHLQEKTLKEHNSLEHFLSKSGGDCTFIHQFIECQNKIIDEGHLTKVEETKLLKENQARVKESDLSDTLSPSKEKSSDDTTDAQMDDQDLNEPIAKVALLKDELQGAQSETEAKQEIQQLHKELIEAQELARTSKQKCFELQALLEEERRAYRVQVEESNKQINVLQAQLQRLQEDIENLREEKESEISSTRNELVSAQNEILSLQQVAEKAASERDTDISALQEELQTVRAELERWRKDASDYEKEIVSLQASFQLRCQQCEEQHKEEATRLKGELEKLKAEWSVLEAECVTLRKENTSLASELQRQEKELSSSQKQSLALTSNISVLEMSRKELEDQMGSLREKHQQDAASLKSQLSEAESQAKDVQKEYERTQTVLSELKAKYEMAEQEKQSITEELKQCKENLKLLQEKGNNPSILQPVPAVFIGLILAFLYWCYGPLW", "length": 824, "header": "tr|A0A8V1A9Q2-1|A0A8V1A9Q2_CHICK Isoform 1 of Sarcolemmal membrane-associated protein OS=Gallus gallus OX=9031 GN=SLMAP PE=1 SV=1 CANONICAL=A0A8V1A9Q2-1" }, "locus": { "chromosome": "12", "start_pos": 9014839, "end_pos": 8941771, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065697.1", "url": "https://www.ensembl.org/id/ENSGALT00010065697.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039963.1", "url": "https://www.ensembl.org/id/ENSGALP00010039963.1" } ] } }, { "isoform_ac": "A0A8V1ACK5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9Q2/entry#A0A8V1ACK5-1", "sequence": { "sequence": "MPSALAIFTCRPNSHPFQERHVYLDEPVKIGRSVARCRPAQNNATFDCKVLSRNHALVWFDHKTGKFYLQDTKSSNGTFINSQRLSRGSEESPPCEIMSGDIIQFGVDVTENTRKVTHGCIVSTIKLFLPDGMEARLRSDVIHAPLPSPVDKVAANTPSMYSQELFQLSQYLQEALHREQMLEQKLATLQRLLAVTQEASDTSWQALIDEDRLLSRLEVMGNQLQACSKNQTEDSIRKELIALQEDKHNYETTAKESLRRVLQEKIEVVRKLSEVERSLSNTEDECTHLKEMNERTQEELRELANKYNGAVNEIKDLSDKLKVAEGKQEEIQQKGLAEKKELQHKIDEMEEREQELQAKIEALQADNDFTNERLTALQVRLEHLQEKTLKEHNSLDKIIDEGHLTKVEETKLLKENQARVKESDLSDTLSPSKEKSSDDTTDAQMDDQDLNEPIAKVALLKDELQGAQSETEAKQEIQQLHKELIEAQELARTSKQKCFELQALLEEERRAYRVQVEESNKQINVLQAQLQRLQEDIENLREEKESEISSTRNELVSAQNEILSLQQVAEKAASERDTDISALQEELQTVRAELERWRKDASDYEKEIVSLQASFQLRCQQCEEQHKEEATRLKGELEKLKAEWSVLEAECVTLRKENTSLASELQRQEKELSSSQKQSLALTSNISVLEMSRKELEDQMGSLREKHQQDAASLKSQLSEAESQAKDVQKEYERTQTVLSELKAKYEMAEQEKQSITEELKQCKENLKLLQEKGNNPSILQPVPAVFIGLILAFLYWCYGPLW", "length": 803, "header": "tr|A0A8V1ACK5-1|A0A8V1ACK5_CHICK Computationally mapped isoform of Sarcolemmal membrane-associated protein OS=Gallus gallus OX=9031 GN=SLMAP PE=1 SV=1 CANONICAL=A0A8V1A9Q2-1" }, "locus": { "chromosome": "12", "start_pos": 9014839, "end_pos": 8941771, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065701.1", "url": "https://www.ensembl.org/id/ENSGALT00010065701.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039967.1", "url": "https://www.ensembl.org/id/ENSGALP00010039967.1" } ] } }, { "isoform_ac": "A0A8V1ACL0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9Q2/entry#A0A8V1ACL0-1", "sequence": { "sequence": "MPSALAIFTCRPNSHPFQERHVYLDEPVKIGRSVARCRPAQNNATFDCKVLSRNHALVWFDHKTGKFYLQDTKSSNGTFINSQRLSRGSEESPPCEIMSGDIIQFGVDVTENTRKVTHGCIVSTIKLFLPDGMEARLRSDVIHAPLPSPVDKVAANTPSMYSQELFQLSQYLQEALHREQMLEQKLATLQRLLAVTQEASDTSWQALIDEDRLLSRLEVMGNQLQACSKNQTEDSIRKELIALQEDKHNYETTAKESLRRVLQEKIEVVRKLSEVERSLSNTEDECTHLKEMNERTQEELRELANKYNGAVNEIKDLSDKLKVAEGKQEEIQQKGLAEKKELQHKIDEMEEREQELQAKIEALQADNDFTNERLTALQVRLEHLQEKTLKEHNSLGIQVDDFIPKINGSTEKDKIIDEGHLTKVEETKLLKDAQMDDQDLNEPIAKVALLKDELQGAQSETEAKQEIQQLHKELIEAQELARTSKQKCFELQALLEEERRAYRVQVEESNKQINVLQAQLQRLQEDIENLREEKESEISSTRNELVSAQNEILSLQQVAEKAASERDTDISALQEELQTVRAELERWRKDASDYEKEIVSLQASFQLRCQQCEEQHKEEATRLKGELEKLKAEWSVLEAECVTLRKENTSLASELQRQEKELSSSQKQSLALTSNISVLEMSRKELEDQMGSLREKHQQDAASLKSQLSEAESQAKDVQKEYERTQTVLSELKAKYEMAEQEKQSITEELKQCKENLKLLQEKGNNPSILQPVPAVFIGLILAFLYWCYGPLW", "length": 793, "header": "tr|A0A8V1ACL0-1|A0A8V1ACL0_CHICK Computationally mapped isoform of Sarcolemmal membrane-associated protein OS=Gallus gallus OX=9031 GN=SLMAP PE=1 SV=1 CANONICAL=A0A8V1A9Q2-1" }, "locus": { "chromosome": "12", "start_pos": 9014839, "end_pos": 8941771, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065706.1", "url": "https://www.ensembl.org/id/ENSGALT00010065706.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039972.1", "url": "https://www.ensembl.org/id/ENSGALP00010039972.1" } ] } }, { "isoform_ac": "A0A8V1AEL9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9Q2/entry#A0A8V1AEL9-1", "sequence": { "sequence": "MPSALAIFTCRPNSHPFQERHVYLDEPVKIGRSVARCRPAQNNATFDCKVLSRNHALVWFDHKTGKFYLQDTKSSNGTFINSQRLSRGSEESPPCEIMSGDIIQFGVDVTENTRKVTHGCIVSTIKLFLPDGMEARLRSDVIHAPLPSPVDKVAANTPSMYSQELFQLSQYLQEALHREQMLEQKLATLQRLLAVTQEASDTSWQALIDEDRLLSRLEVMGNQLQACSKNQTEDSIRKELIALQEDKHNYETTAKESLRRVLQEKIEVVRKLSEVERSLSNTEDECTHLKEMNERTQEELRELANKYNGAVNEIKDLSDKLKVAEGKQEEIQQKGLAEKKELQHKIDEMEEREQELQAKIEALQADNDFTNERLTALQVRLEHLQEKTLKEHNSLENQARVKESDLSDTLSPSKEKSSDDTTDAQMDDQDLNEPIAKVALLKDELQGAQSETEAKQEIQQLHKELIEAQELARTSKQKCFELQALLEEERRAYRVQVEESNKQINVLQAQLQRLQEDIENLREEKESEISSTRNELVSAQNEILSLQQVAEKAASERDTDISALQEELQTVRAELERWRKDASDYEKEIVSLQASFQLRCQQCEEQHKEEATRLKGELEKLKAEWSVLEAECVTLRKENTSLASELQRQEKELSSSQKQSLALTSNISVLEMSRKELEDQMGSLREKHQQDAASLKSQLSEAESQAKDVQKEYERTQTVLSELKAKYEMAEQEKQSITEELKQCKENLKLLQEKGNNPSILQPVPAVFIGLILAFLYWCYGPLW", "length": 784, "header": "tr|A0A8V1AEL9-1|A0A8V1AEL9_CHICK Computationally mapped isoform of Sarcolemmal membrane-associated protein OS=Gallus gallus OX=9031 GN=SLMAP PE=1 SV=1 CANONICAL=A0A8V1A9Q2-1" }, "locus": { "chromosome": "12", "start_pos": 9014839, "end_pos": 8941771, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065699.1", "url": "https://www.ensembl.org/id/ENSGALT00010065699.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039965.1", "url": "https://www.ensembl.org/id/ENSGALP00010039965.1" } ] } }, { "isoform_ac": "A0A8V1AEM4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9Q2/entry#A0A8V1AEM4-1", "sequence": { "sequence": "MPSALAIFTCRPNSHPFQERHVYLDEPVKIGRSVARCRPAQNNATFDCKVLSRNHALVWFDHKTGKFYLQDTKSSNGTFINSQRLSRGSEESPPCEIMSGDIIQFGVDVTENTRKVTHGCIVSTIKLFLPDGMEARLRSDVIHAPLPSPVDKVAANTPSMYSQELFQLSQYLQEALHREQMLEQKLATLQRLLAVTQEASDTSWQALIDEDRLLSRLEVMGNQLQACSKNQTEDSIRKELIALQEDKHNYETTAKESLRRVLQEKIEVVRKLSEVERSLSNTEDECTHLKEMNERTQEELRELANKYNGAVNEIKDLSDKLKVAEGKQEEIQQKGLAEKKELQHKIDEMEEREQELQAKIEALQADNDFTNERLTALQVRLEHLQEKTLKEHNSLGIQVDDFIPKINGSTEKENQARVKESDLSDTLSPSKEKSSDDTTDAQMDDQDLNEPIAKVALLKDELQGAQSETEAKQEIQQLHKELIEAQELARTSKQKCFELQALLEEERRAYRVQVEESNKQINVLQAQLQRLQEDIENLREEKESEISSTRNELVSAQNEILSLQQVAEKAASERDTDISALQEELQTVRAELERWRKDASDYEKEIVSLQASFQLRCQQCEEQHKEEATRLKGELEKLKAEWSVLEAECVTLRKENTSLASELQRQEKELSSSQKQSLALTSNISVLEMSRKELEDQMGSLREKHQQDAASLKSQLSEAESQAKDVQKEYERTQTVLSELKAKYEMAEQEKQSITEELKQCKENLKLLQEKGNNPSILQPVPAVFIGLILAFLYWCYGPLW", "length": 801, "header": "tr|A0A8V1AEM4-1|A0A8V1AEM4_CHICK Computationally mapped isoform of Sarcolemmal membrane-associated protein OS=Gallus gallus OX=9031 GN=SLMAP PE=1 SV=1 CANONICAL=A0A8V1A9Q2-1" }, "locus": { "chromosome": "12", "start_pos": 9014839, "end_pos": 8941771, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065704.1", "url": "https://www.ensembl.org/id/ENSGALT00010065704.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039970.1", "url": "https://www.ensembl.org/id/ENSGALP00010039970.1" } ] } }, { "isoform_ac": "A0A8V1AEM8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9Q2/entry#A0A8V1AEM8-1", "sequence": { "sequence": "MPSALAIFTCRPNSHPFQERHVYLDEPVKIGRSVARCRPAQNNATFDCKVLSRNHALVWFDHKTGKFYLQDTKSSNGTFINSQRLSRGSEESPPCEIMSGDIIQFGVDVTENTRKVTHGCIVSTIKLFLPDGMEARLRSDVIHAPLPSPVDKVAANTPSMYSQELFQLSQYLQEALHREQMLEQKLATLQRLLAVTQEASDTSWQALIDEDRLLSRLEVMGNQLQACSKNQTEDSIRKELIALQEDKHNYETTAKESLRRVLQEKIEVVRKLSEVERSLSNTEDECTHLKEMNERTQEELRELANKYNGAVNEIKDLSDKLKVAEGKQEEIQQKGLAEKKELQHKIDEMEEREQELQAKIEALQADNDFTNERLTALQDKIIDEGHLTKVEETKLLKENQARVKESDLSDTLSPSKEKSSDDTTDAQMDDQDLNEPIAKVALLKALLEEERRAYRVQVEESNKQINVLQAQLQRLQEDIENLREEKESEISSTRNELVSAQNEILSLQQVAEKAASERDTDISALQEELQTVRAELERWRKDASDYEKEIVSLQASFQLRCQQCEEQHKEEATRLKGELEKLKAEWSVLEAECVTLRKENTSLASELQRQEKELSSSQKQSLALTSNISVLEMSRKELEDQMGSLREKHQQDAASLKSQLSEAESQAKDVQKEYERTQTVLSELKAKYEMAEQEKQSITEELKQCKENLKLLQEKGNNPSILQPVPAVFIGLILAFLYWCYGPLW", "length": 745, "header": "tr|A0A8V1AEM8-1|A0A8V1AEM8_CHICK Computationally mapped isoform of Sarcolemmal membrane-associated protein OS=Gallus gallus OX=9031 GN=SLMAP PE=1 SV=1 CANONICAL=A0A8V1A9Q2-1" }, "locus": { "chromosome": "12", "start_pos": 9014839, "end_pos": 8941771, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065709.1", "url": "https://www.ensembl.org/id/ENSGALT00010065709.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039975.1", "url": "https://www.ensembl.org/id/ENSGALP00010039975.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9Q2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9Q2" } ], "pmid": "" }, { "name": "mitochondrial membrane", "id": "GO:0031966", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031966", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9Q2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9Q2" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9Q2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9Q2" } ], "pmid": "" }, { "name": "sarcolemma", "id": "GO:0042383", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042383", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9Q2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9Q2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "regulation of membrane depolarization during cardiac muscle cell action potential", "id": "GO:1900825", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900825", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9Q2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9Q2" } ], "pmid": "" }, { "name": "negative regulation of hippo signaling", "id": "GO:0035331", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035331", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9Q2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9Q2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 230, "end_pos": 232, "annotation": "n_glycosylation_sequon" }, { "start_pos": 43, "end_pos": 45, "annotation": "n_glycosylation_sequon" }, { "start_pos": 679, "end_pos": 681, "annotation": "n_glycosylation_sequon" }, { "start_pos": 706, "end_pos": 708, "annotation": "n_glycosylation_sequon" }, { "start_pos": 76, "end_pos": 78, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1A9Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9Q2" }, { "id": "PS50006", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50006" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "FHA", "eco_id": "ECO_0000259", "start_pos": 28, "end_pos": 85, "start_aa": "Val", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 230, "end_pos": 232 }, { "start_pos": 43, "end_pos": 45 }, { "start_pos": 679, "end_pos": 681 }, { "start_pos": 706, "end_pos": 708 }, { "start_pos": 76, "end_pos": 78 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A9S0-1", "uniprot_ac": "A0A8V1A9S0", "uniprot_id": "A0A8V1A9S0_CHICK", "mass": { "chemical_mass": 86443.0, "monoisotopic_mass": 86443.0 }, "refseq": {}, "gene_names": [ { "name": "PLEKHM3", "type": "recommended", "evidence": [ { "id": "A0A8V1A9S0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9S0" } ] } ], "protein_names": [ { "name": "Pleckstrin homology domain containing M3", "type": "synonym", "evidence": [ { "id": "A0A8V1A9S0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9S0/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9S0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9S0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PLEKHM3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9S0", "locus": { "chromosome": "7", "start_pos": 11764478, "end_pos": 11645542, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010025312", "url": "https://www.ensembl.org/id/ENSGALG00010025312" } ] } } ], "crossref": [ { "id": "A0A8V1A9S0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A9S0", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd13327", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13327", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd14674", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14674", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "101748748", "url": "https://www.ncbi.nlm.nih.gov/gene/101748748", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025258", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025258", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037812", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037812", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051366", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051366", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "CVHRELH", "url": "https://omabrowser.org/oma/group/CVHRELH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A2B0", "url": "https://www.orthodb.org/?gene=A0A8V1A2B0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A2B7", "url": "https://www.orthodb.org/?gene=A0A8V1A2B7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A4M1", "url": "https://www.orthodb.org/?gene=A0A8V1A4M1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A4M8", "url": "https://www.orthodb.org/?gene=A0A8V1A4M8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A6Z6", "url": "https://www.orthodb.org/?gene=A0A8V1A6Z6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A9S0", "url": "https://www.orthodb.org/?gene=A0A8V1A9S0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12326", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12326", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12326:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12326:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00169", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00169", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13901", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13901", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1A2B0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2B0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A2B0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2B0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A2B7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2B7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A2B7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2B7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A4M1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4M1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A4M1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4M1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A4M8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4M8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A4M8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4M8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A6Z6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6Z6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A6Z6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6Z6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A9S0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9S0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A9S0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9S0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEALEVDDISPALEVTEDFFNSFDTKLEKIVQPSGVFGVQDVPELVGHEVFDQITESRNLRNVASLAKSSLIWDHCKNGLLETKAQTVFSAKDQHVVQRGTAADNRAWAGEGETAAFNIFNICQRRRDRPRSVNDILVQNEEASTFKPGHNRSRSDISHVNWGVVFTGTSLQQPALPGQDNNCALLSYLALTKGQDIQGNTEHKPTFPNILKKGYLEIRRDNDSYWQTCYAELSPYKLYLYCLDSSGNQTLPTVYPLMHFQRVTVTGSIEAKVVEAVLSDNSQLQLKAESSWEALDWGRKLWEVMRASVSTFTRQPEQVENVPEPDNSSDRSQTNGLVEKPVELLLSMNLTENTKEYQNILKSGTLYRLTVQNNWKAFTFVLNRSYLMAFQPGRLDEDPLLSYNVDVCLSVQTDTQDGCDSCFQVIFPQDVLRLRAETRQRAQEWMEALKTAANVTRSLGQNPQVTLRNKRGDRPFGNDFRKSKRQSVTTSFLSILTTLSLERGLTVQSFKCCQRSIGLSNGKAKVCSYSGWYYCCTCHVDDSFLIPARLVHNWDTSKYKVSKQAKEFLEYVYEEPLIDIQQENPMLYKHVESLATVVRLRQQLKSLRAYLFSCRAAVAEDLRRRIFPREYLLQQIHLYSLADLQQVIEGKLAPFLGKVIKFATSHVYSCSLCSQKGFICEICNNGEILYPFEDISTSRCESCGAVFHSECKVKAVPCPRCVRKELQKKQKSFWRRLNMDENFEESCNMFELSYQNT", "length": 757, "header": "tr|A0A8V1A9S0-1|A0A8V1A9S0_CHICK Isoform 1 of Pleckstrin homology domain containing M3 OS=Gallus gallus OX=9031 GN=PLEKHM3 PE=4 SV=1 CANONICAL=A0A8V1A9S0-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A2B0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9S0/entry#A0A8V1A2B0-1", "sequence": { "sequence": "MEALEVDDISPALEVTEDFFNSFDTKLEKIVQPSGVFGVQDVPELVGHEVFDQITESRNLRNVASLAKSSLIWDHCKNGLLETKAQTVFSAKDQHVVQRGTAADNRAWAGEGETAAFNIFNICQRRRDRPRSVNDILVQNEEASTFKPGHNRSRSDISHVNWGVVFTGTSLQQPALPGQDNNCALLSYLALTKGQDIQGNTEHKPTFPNILKKGYLEIRRDNDSYWQTCYAELSPYKLYLYCLDSSGNQTLPTVYPLMHFQRVTVTGSIEAKVVEAVLSDNSQLQLKAESSWEALDWGRKLWEVMRASVSTFTRQPEQVENVPEPDNSSDRSQTNGLVEKPVELLLSMNLTENTKEYQNILKSGTLYRLTVQNNWKAFTFVLNRSYLMAFQPGRLDEDPLLSYNVDVCLSVQTDTQDGCDSCFQVIFPQDVLRLRAETRQRAQEWMEALKTAANVTRSLGQNPQVTLRNKRGDRPFGNDFRKSKRQSVTTSFLSILTTLSLERGLTVQSFKCAGCQRSIGLSNGKAKVCSYSGWYYCCTCHVDDSFLIPARLVHNWDTSKYKVSKQAKEFLEYVYEEPLIDIQQENPMLYKHVESLATVVRLRQQLKSLRAYLFSCRAAVAEDLRRRIFPREYLLQQIHLYSLADLQQEVTIKSRDTFLSLIWQAAIQTTGSPGVKNIHLGPYSIFIIPYTSRTL", "length": 695, "header": "tr|A0A8V1A2B0-1|A0A8V1A9S0_CHICK Computationally mapped isoform of Pleckstrin homology domain containing M3 OS=Gallus gallus OX=9031 GN=PLEKHM3 PE=4 SV=1 CANONICAL=A0A8V1A9S0-1" }, "locus": { "chromosome": "7", "start_pos": 11712712, "end_pos": 11653776, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010061777.1", "url": "https://www.ensembl.org/id/ENSGALT00010061777.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038134.1", "url": "https://www.ensembl.org/id/ENSGALP00010038134.1" } ] } }, { "isoform_ac": "A0A8V1A2B7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9S0/entry#A0A8V1A2B7-1", "sequence": { "sequence": "MEALEVDDISPALEVTEDFFNSFDTKLEKIVQPSGVFGVQDVPELVGHEVFDQITESRNLRNVASLAKSSLIWDHCKNGLLETKAQTVFSAKDQHVVQRGTAADNRAWAGEGETAAFNIFNICQRRRDRPRSVNDILVQNEEASTFKPGHNRSRSDISHVNWGVVFTGTSLQQPALPGQDNNCALLSYLALTKGQDIQGNTEHKPTFPNILKKGYLEIRRDNDSYWQTCYAELSPYKLYLYCLDSSGNQTLPTVYPLMHFQRVTVTGSIEAKVVEAVLSDNSQLQLKAESSWEALDWGRKLWEVMRASVSTFTRQPEQVENVPEPDNSSDRSQTNGLVEKPVELLLSMNLTENTKEYQNILKSGTLYRLTVQNNWKAFTFVLNRSYLMAFQPGRLDEDPLLSYNVDVCLSVQTDTQDGCDSCFQVIFPQDVLRLRAETRQRAQEWMEALKTAANVTRSLGQNPQVTLRNKRGDRPFGNDFRKSKRQSVTTSFLSILTTLSLERGLTVQSFKCAGCQRSIGLSNGKAKVCSYSGWYYCCTCHVDDSFLIPARLVHNWDTSKYKVSKQAKEFLEYVYEEPLIDIQQENPMLYKHVESLATVVRLRQQLKSLRAYLFSCRAAVAEDLRRRIFPREYLLQQIHLYSLADLQQVIEGKLAPFLGKVIKFATSHVYSCSLCSQKGFICEICNNGEILYPFEDISTSRCESCGAVFHSECKVKAVPCPRHLWTASP", "length": 729, "header": "tr|A0A8V1A2B7-1|A0A8V1A9S0_CHICK Computationally mapped isoform of Pleckstrin homology domain containing M3 OS=Gallus gallus OX=9031 GN=PLEKHM3 PE=4 SV=1 CANONICAL=A0A8V1A9S0-1" }, "locus": { "chromosome": "7", "start_pos": 11733896, "end_pos": 11653776, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010061787.1", "url": "https://www.ensembl.org/id/ENSGALT00010061787.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038139.1", "url": "https://www.ensembl.org/id/ENSGALP00010038139.1" } ] } }, { "isoform_ac": "A0A8V1A4M1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9S0/entry#A0A8V1A4M1-1", "sequence": { "sequence": "MEALEVDDISPALEVTEDFFNSFDTKLEKIVQPSGVFGVQDVPELVGHEVFDQITESRNLRNVASLAKSSLIWDHCKNGLLETKAQTVFSAKDQHVVQRGTAADNRAWAGEGETAAFNIFNICQRRRDRPRSVNDILVQNEEASTFKPGHNRSRSDISHVNWGVVFTGTSLQQPALPGQDNNCALLSYLALTKGQDIQGNTEHKPTFPNILKKGYLEIRRDNDSYWQTCYAELSPYKLYLYCLDSSGNQTLPTVYPLMHFQRVTVTGSIEAKVVEAVLSDNSQLQLKAESSWEALDWGRKLWEVMRASVSTFTRQPEQVENVPEPDNSSDRSQTNGLVEKPVELLLSMNLTENTKEYQNILKSGTLYRLTVQNNWKAFTFVLNRSYLMAFQPGRLDEDPLLSYNVDVCLSVQTDTQDGCDSCFQVIFPQDVLRLRAETRQRAQEWMEALKTAANVTRSLGQNPQVTLRNKRGDRPFGNDFRKSKRQSVTTSFLSILTTLSLERGLTVQSFKCAGCQRSIGLSNGKAKVCSYSGWYYCCTCHVDDSFLIPARLVHNWDTSKYKVSKQAKEFLEYVYEEPLIDIQQENPMLYKHVESLATVVRLRQQLKSLRAYLFSCRAAVAEDLRRRIFPREYLLQQIHLYSLADLQQVIEGKLAPFLGKVIKFATSHVYSCSLCSQKGFICEICNNGEILYPFEDISTSRHLWTASP", "length": 708, "header": "tr|A0A8V1A4M1-1|A0A8V1A9S0_CHICK Computationally mapped isoform of Pleckstrin homology domain containing M3 OS=Gallus gallus OX=9031 GN=PLEKHM3 PE=4 SV=1 CANONICAL=A0A8V1A9S0-1" }, "locus": { "chromosome": "7", "start_pos": 11733896, "end_pos": 11653776, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010061783.1", "url": "https://www.ensembl.org/id/ENSGALT00010061783.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038136.1", "url": "https://www.ensembl.org/id/ENSGALP00010038136.1" } ] } }, { "isoform_ac": "A0A8V1A4M8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9S0/entry#A0A8V1A4M8-1", "sequence": { "sequence": "MEALEVDDISPALEVTEDFFNSFDTKLEKIVQPSGVFGVQDVPELVGHEVFDQITESRNLRNVASLAKSSLIWDHCKNGLLETKAQTVFSAKDQHVVQRGTAADNRAWAGEGETAAFNIFNICQRRRDRPRSVNDILVQNEEASTFKPGHNRSRSDISHVNWGVVFTGTSLQQPALPGQDNNCALLSYLALTKGQDIQGNTEHKPTFPNILKKGYLEIRRDNDSYWQTCYAELSPYKLYLYCLDSSGNQTLPTVYPLMHFQRVTVTGSIEAKVVEAVLSDNSQLQLKAESSWEALDWGRKLWEVMRASVSTFTRQPEQVENVPEPDNSSDRSQTNGLVEKPVELLLSMNLTENTKEYQNILKSGTLYRLTVQNNWKAFTFVLNRSYLMAFQPGRLDEDPLLSYNVDVCLSVQTDTQDGCDSCFQVIFPQDVLRLRAETRQRAQEWMEALKTAANVTRSLGQNPQVTLRNKRGDRPFGNDFRKSKRQSVTTSFLSILTTLSLERGLTVQSFKCAGCQRSIGLSNGKAKVCSYSGWYYCCTCHVDDSFLIPARLVHNWDTSKYKVSKQAKEFLEYVYEEPLIDIQQENPMLYKHVESLATVVRLRQQLKSLRAYLFSCRAAVAEDLRRRIFPREYLLQQIHLYSLADLQQVIEGKLAPFLGKVIKFATSHVYSCSLCSQKGFICEICNNGEILYPFEDISTSRNRCTPLLEAHLWGKVHASGRALLLSLGLQPSSQAQLSAWDSLRNTSARGLKIVLQTSHSED", "length": 762, "header": "tr|A0A8V1A4M8-1|A0A8V1A9S0_CHICK Computationally mapped isoform of Pleckstrin homology domain containing M3 OS=Gallus gallus OX=9031 GN=PLEKHM3 PE=4 SV=1 CANONICAL=A0A8V1A9S0-1" }, "locus": { "chromosome": "7", "start_pos": 11763533, "end_pos": 11653776, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010061789.1", "url": "https://www.ensembl.org/id/ENSGALT00010061789.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038141.1", "url": "https://www.ensembl.org/id/ENSGALP00010038141.1" } ] } }, { "isoform_ac": "A0A8V1A6Z6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9S0/entry#A0A8V1A6Z6-1", "sequence": { "sequence": "MEALEVDDISPALEVTEDFFNSFDTKLEKIVQPSGVFGVQDVPELVGHEVFDQITESRNLRNVASLAKSSLIWDHCKNGLLETKAQTVFSAKDQHVVQRGTAADNRAWAGEGETAAFNIFNICQRRRDRPRSVNDILVQNEEASTFKPGHNRSRSDISHVNWGVVFTGTSLQQPALPGQDNNCALLSYLALTKGQDIQGNTEHKPTFPNILKKGYLEIRRDNDSYWQTCYAELSPYKLYLYCLDSSGNQTLPTVYPLMHFQRVTVTGSIEAKVVEAVLSDNSQLQLKAESSWEALDWGRKLWEVMRASVSTFTRQPEQVENVPEPDNSSDRSQTNGLVEKPVELLLSMNLTENTKEYQNILKSGTLYRLTVQNNWKAFTFVLNRSYLMAFQPGRLDEDPLLSYNVDVCLSVQTDTQDGCDSCFQVIFPQDVLRLRAETRQRAQEWMEALKTAANVTRSLGQNPQVTLRNKRGDRPFGNDFRKSKRQSVTTSFLSILTTLSLERGLTVQSFKCAGCQRSIGLSNGKAKVCSYSGWYYCCTCHVDDSFLIPARLVHNWDTSKYKVSKQAKEFLEYVYEEPLIDIQQENPMLYKHVESLATVVRLRQQLKSLRAYLFSCRAAVAEDLRRRIFPREYLLQQIHLYSLADLQQVIEGKLAPFLGKVIKFATSHVYSCSLCSQKGFICEICNNGEILYPFEDISTSSCTRFLAQRGHRLGSRWEELLSKAL", "length": 725, "header": "tr|A0A8V1A6Z6-1|A0A8V1A6Z6_CHICK Computationally mapped isoform of Pleckstrin homology domain containing M3 OS=Gallus gallus OX=9031 GN=PLEKHM3 PE=4 SV=1 CANONICAL=A0A8V1A9S0-1" }, "locus": { "chromosome": "7", "start_pos": 11713922, "end_pos": 11653776, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010061779.1", "url": "https://www.ensembl.org/id/ENSGALT00010061779.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038135.1", "url": "https://www.ensembl.org/id/ENSGALP00010038135.1" } ] } }, { "isoform_ac": "A0A8V1A9S0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9S0/entry#A0A8V1A9S0-1", "sequence": { "sequence": "MEALEVDDISPALEVTEDFFNSFDTKLEKIVQPSGVFGVQDVPELVGHEVFDQITESRNLRNVASLAKSSLIWDHCKNGLLETKAQTVFSAKDQHVVQRGTAADNRAWAGEGETAAFNIFNICQRRRDRPRSVNDILVQNEEASTFKPGHNRSRSDISHVNWGVVFTGTSLQQPALPGQDNNCALLSYLALTKGQDIQGNTEHKPTFPNILKKGYLEIRRDNDSYWQTCYAELSPYKLYLYCLDSSGNQTLPTVYPLMHFQRVTVTGSIEAKVVEAVLSDNSQLQLKAESSWEALDWGRKLWEVMRASVSTFTRQPEQVENVPEPDNSSDRSQTNGLVEKPVELLLSMNLTENTKEYQNILKSGTLYRLTVQNNWKAFTFVLNRSYLMAFQPGRLDEDPLLSYNVDVCLSVQTDTQDGCDSCFQVIFPQDVLRLRAETRQRAQEWMEALKTAANVTRSLGQNPQVTLRNKRGDRPFGNDFRKSKRQSVTTSFLSILTTLSLERGLTVQSFKCCQRSIGLSNGKAKVCSYSGWYYCCTCHVDDSFLIPARLVHNWDTSKYKVSKQAKEFLEYVYEEPLIDIQQENPMLYKHVESLATVVRLRQQLKSLRAYLFSCRAAVAEDLRRRIFPREYLLQQIHLYSLADLQQVIEGKLAPFLGKVIKFATSHVYSCSLCSQKGFICEICNNGEILYPFEDISTSRCESCGAVFHSECKVKAVPCPRCVRKELQKKQKSFWRRLNMDENFEESCNMFELSYQNT", "length": 757, "header": "tr|A0A8V1A9S0-1|A0A8V1A9S0_CHICK Isoform 1 of Pleckstrin homology domain containing M3 OS=Gallus gallus OX=9031 GN=PLEKHM3 PE=4 SV=1 CANONICAL=A0A8V1A9S0-1" }, "locus": { "chromosome": "7", "start_pos": 11726728, "end_pos": 11653776, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010061786.1", "url": "https://www.ensembl.org/id/ENSGALT00010061786.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038138.1", "url": "https://www.ensembl.org/id/ENSGALP00010038138.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0AAA9TU17-1", "protein_name": "Pleckstrin homology domain-containing family M member 3", "gene_name": "PLEKHM3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MEALEVDDISPALEVTEDFFNTFDNKLEKAVQQAEVYGIQEVPELVGREVLGNIDNGAIRNVTSLGQGGVIWDHCKTRLLDTKVPNVFPAKEQFMVQKGTTPDNLSWMEQKEASTFNFFNICQRRRDRPRSVNDLLDETSTFKPGHARSRSDITQVDWRVVLKTMPLQQEVSLQGPHFARPSLLLSSSNKVEDAQGNTEHKPAFPNILKKGYLEIRKEHDSYWQSCYAELSPYSLYFYSLDSSGNQNLYATYQLSHFQSISVLGNLEARLVDTVLYDNTQLQLKAESPWEALDWGQKLWEGVHAAAPAYMGRPGELANSPGLGHHVDCPQNHCLQKKSRELLMPSPVLDSPKQYQNILKSGTLYRLTMQNNWKAFTFVLSRTCLMAFPPGKLDEDPLLSYNVDVCLAVQLDHLDDCDSCFQVIFPQDVLRLRAETRQRAQEWMEALKTAANTARSSEQNLQVTLRTKPRDQMGGHELRKNKRQSVTTSFLSILTTLSLERGLTAQSFKCAGCQRSIGLSNGKAKVCSYSGWYYCSSCHVDDSFLIPARIVHNWDTSKYKVSKQAKEFLEYVYEEPLIDIQQQNPMLYGHAEPLATVVRLRQRLKSLRAYLFSCRAAVAEDLRRRIFPREYLLQQIHLYSLADLQQVIEGKLAPFLGKVIKFATSHVYSCSLCSQKGFICEICNNGEILYPFEDISTSRCESCGAVFHAECKEKSVPCPRCVRRELQMKQKSFWRRLNMDESLEEACNMFELSYQNT", "length": 756 }, "evidence": [ { "id": "A0A8V1A9S0", "url": "https://omabrowser.org/oma/group/A0A8V1A9S0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0ABK0L3E5-1", "protein_name": "Pleckstrin homology domain-containing family M member 3", "gene_name": "Plekhm3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEALEVDDISPALEVTEDFFSTFDSKLGKAVQQAEVYGVQEVPELVGHEVLGNITDNGALRSVASLGKGTMIWDHCKSRLLETKAQNVFPAKEQLMVQRGTAPDNLSWMEQKEASTFNFFNICQRRRDRPRSVNDLLDETTTFKPGHARSRSDVTHVDWRVVLSTMPLQQQQQQQQASLHGPHFPRPSFLLSSSNKVEDAQGNTEHKQTFPNILKKGYLEIRKNHDSYWQSCYAELSPYNLNFYSLDSSGNQNLYATYQLSHFQSISVLGNLEARMVDTVLYDNSQLQLKAESPWEALDWGQKLWEVVHAAVPNYMARQEEKANSPGLGHHVDCAQNHCLQKKSSGLLASPVLDSPKQYQNILKSGTLYRLTVQNNWKAFTFVLSKAYLMAFHPGKLDEDPLLSYNVDVCLAVQTDNLDGCDSCFQVIFPQDVLRLRAETRQRAQEWMEALKTAANAARSSEQNLQVTLRNKPKDQLGGHELRKNKRQSVTTSFLSILTTLSLERGLTAQSFKCAGCQRPIGLSNGKAKVCNYSGWYYCSSCHVDDSFLIPARIVHNWDTSKYKVSKQAKEFLEYVYEEPLIDIQQENPMLYLHAEPLATVARLRQRLKSLRAYLFSCRAAVAEDLRRRIFPREYLLQQIHLYSLADLQQVIEGKLAPFLGKVIKFATAHVYSCSLCSQKGFICEICNNGEILYPFEDISTSRCESCGSVFHSECKEKSVPCPRCVRRELQKKQKSFWRQLNVDESLEEACTMFELSYQNT", "length": 761 }, "evidence": [ { "id": "A0A8V1A9S0", "url": "https://omabrowser.org/oma/group/A0A8V1A9S0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3HU57-1", "protein_name": "Pleckstrin homology domain-containing family M member 3", "gene_name": "Plekhm3", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEALEVDDISPALEVTEDFFSTFDSKLEKAVQQAEVYGIQEVPELVGHEVFSNITDNGALRNVVSLGSKGNMIWDHCKSRLLETKAQNVFPAKEQLMVQRGTAPDNLSWMEQKEASTFNFFNICQRRRDRPRSVNDLLDESTTFKPGHARSRSDVTHVDWRLVLGTMPLQQQQLSLQGPHFARPSFLLPSPSKVEDAQGNTEHKQTFPNILKKGYLEIRKNHDSYWQSCYAELSPYNLHFYSLDSSGNQSLYATYQLSQFQSISVLGNLEARMVDTVLSDNSQLQLKAESPWEALDWGQKLWEVVHAAAPNYMGRPDEPANSPGLGSQNHCLQKKSSGLLSSPVLHSPKQYQNILKSGTLYRLTVQNNWKAFTFVLSKAYLMAFHPGKLDEDPLLSYNVDVCLAVQIDNLDGCDSCFQVIFPQDVLRLRAETRQRAQEWMEALKTAANAARSSEQNLQVTLRNKPKDQIGGHELRKNKRQSVTTSFLSILTTLSLERGLTAQSFKCAGCQRSIGLSNGKAKVCNYSGWYYCSSCHVDDSFLIPARVVHNWDTSKYKVSKQAKEFLEYVYEEPLIDIQQENPMLYLHAEPLATVVRLRQQLKSLRAYLFSCRAAVAEDLRRRIFPREYLLQQIHLYSLADLQQVIEGKLAPFLGKVIKFATSHVYSCSLCSQKGFICEICNNGEILYPFEDISTSRCESCGAVFHSECKEKSVPCPRCVRRELQKKQKSFWRQLNVDESLEEACTMFELSYQNT", "length": 753 }, "evidence": [ { "id": "A0A8V1A9S0", "url": "https://omabrowser.org/oma/group/A0A8V1A9S0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "I3L6K9-1", "protein_name": "Pleckstrin homology domain-containing family M member 3", "gene_name": "PLEKHM3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEALEVDDISPALEVTEEFFSTFDSKLEKAVQHAEVYGIQEVPELVGHEVLGNIDNGAIRNVSSLGRGAVIWDHCKSRLLETKAQNVFPAKEQFTVQKGTTPDNLSWMEQKEASTFNFFNICQRRKDRPRSVNDLLDETSTFKPGHARSRSDITQVDWRVGLKTTPLQQQQQQQPSLLGSHFTRPSFLLPSSNKVEDAQGNTEHKQAFPNILKKGYLEIRKNHDSYWQSCYAELSPYNLYFYSLDSSGNQNLYATYQLSHFQSISVLGNLEARLVDTVLYDNTQLQLKAESPWEALDWGQKLWEGVHAAVPAYLGRPDELANSPGLGHHVDCAQNHCLQKKSSQLLMPSPVLDGPKQYQNILKSGTLYRLTVQNNWKAFTFVLSRSYLMAFQPGKLDEDPLLSYNVDVCLAVQLDNLDDCDSCFQVIFPQDVLRLRAETRQRAQEWMEALKTAANAARSSEQNPQVTLRSKPKDQMGGHELRKNKRQSVTTSFLSILTTLSLERGLTAQSFKCAGCQRSIGLSYGKAKVCNYSGWYYCSSCHVDDSFLIPARIVHNWDTSKYKVSKQAKEFLEYVFEEPLIDIQQENPMLYGHAEPLATVVRLRQRLKSLRAYLFSCRAAVAEDLRRRIFPREYLLQQIHLYSLADLQQVIEGKLAPFLGKIIKFATSHVYSCSLCSQKGFICEICNNGEILYPFEDISTSRCESCGAVFHSECKEKSVPCPRCVRRELQKKQKSFWRRLNMDESLEEACNMFELSYQNT", "length": 760 }, "evidence": [ { "id": "A0A8V1A9S0", "url": "https://omabrowser.org/oma/group/A0A8V1A9S0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q6ZWE6-1", "protein_name": "Pleckstrin homology domain-containing family M member 3", "gene_name": "PLEKHM3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEALEVDDISPALEVTEEFFSTLDSNLEKAVQQAEVYGIQEVPELVGHEVLSNITDNGAMRNVTSLGKGGMIWDHCKSRLLETKAQNVFPAKEQFMVQRGTTPDNLSWMEQKEASTFNFFNICQRRRDRPRSVNDLLDETSTFKPGHARSRSDITQVDWRVVLKTTPLQQQQQQQPLLQGPHVTRPSFLLPSPNKIEDAQGNTEHKQTFPNILKKGYLEIRKDHDSYWQSCYAELSPYNLYFYSLDSSGNQNLYATYQLSHFQSISVLGNLEARMVDTVLYDNTQLQLKAESPWEALDWGQKLWEVVHAAVPGYMGRQNELTISPGLGHHDDYTQNHSFQKKTSGLLPPSPVLDSSKQYQNILKSGTLYRLTVQNNWKAFTFVLSRAYLMAFQPGKLDEDPLLSYNVDVCLAVQMDNLDGCDSCFQVIFPQDVLRLRAETRQRAQEWMEALKIAANVARSSEQNLQVTLRNKPKDQMGGHELRKNKRQSVTTSFLSILTTLSLERGLTAQSFKCAGCQRSIGLSNGKAKVCNYSGWYYCSSCHVDDSFLIPARIVHNWDTSKYKVSKQAKEFLEYVYEEPLIDIQQENAMLYHHAEPLAAVLRLRQRLKSLRAYLFSCRAAVAEDLRRRIFPREYLLQQIHLYSLADLQQVIEGKLAPFLGKVIKFATSHVYSCSLCSQKGFICEICNNGEILYPFEDISTSRCESCGAVFHSECKEKSVPCPRCVRRELQKKQKSFWQRLNMDESLEEACTMFELSYQNT", "length": 761 }, "evidence": [ { "id": "A0A8V1A9S0", "url": "https://omabrowser.org/oma/group/A0A8V1A9S0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BM47-1", "protein_name": "Pleckstrin homology domain-containing family M member 3", "gene_name": "Plekhm3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEALEVDDISPALEVTEDFFSTFDSKLEKAVQQAEVYGIQEVPELVGHEVLGNIADNGALRSVASLGKGTMIWDHCKSRLLETKAQNVFPAKEQLMVQRGTAPDNLSWMAQKEASTFNFFNICQRRRDRPRSVNDLLDETTTFKPGHARSRSDVTHVDWRVVLSTMPLQQQQQQQQASLQGIHFPGPSFLLSSPSKVEDAQGNTEHKQTFPNILKKGYLEIRKNHDSYWQSCYAELSPYNLNFYSLDSSGNQNLYATYQLSHFQSISVLGNLEARMVDTVLYDNSQLQLKAESPWEALDWGQKLWEVVHAAVPNYMGRQGEMANSPGLIHHGDCAQNHCLQKKSSGLLASPVLDSPKQYQNILKSGTLYRLTVQNNWKAFTFVLSKAYLMAFHPGKLDEDPLLSYNVDVCLAVQIDNLDGCDSCFQVIFPQDVLRLRAETRQRAQEWMEALKTAANAARSSEQNLQVTLRNKPKDQLDGRELRKNKRQSVTTSFLSILTTLSLERGLTAQSFKCAGCQRSIGLSNGKAKVCNYSGWYYCSSCHVDDSFLIPARIVHNWDTSKYKVSKQAKEFLEYVYEEPLIDIQQENPMLYLHAEPLATVVRLRQRLKSLRAYLFSCRAAVAEDLRRRIFPREYLLQQIHLYSLADLQQVIEGKLAPFLGKVIKFATAHVYSCSLCSQKGFICEICNNGEILYPFEDISTSRCESCGAVFHSECKEKSVPCPRCVRRELQKKQKSFWRQLNVDESLEEACAMFELSYQST", "length": 761 }, "evidence": [ { "id": "A0A8V1A9S0", "url": "https://omabrowser.org/oma/group/A0A8V1A9S0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9S0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9S0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9S0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9S0" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9S0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9S0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "myoblast differentiation", "id": "GO:0045445", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045445", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9S0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9S0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 151, "end_pos": 153, "annotation": "n_glycosylation_sequon" }, { "start_pos": 222, "end_pos": 224, "annotation": "n_glycosylation_sequon" }, { "start_pos": 248, "end_pos": 250, "annotation": "n_glycosylation_sequon" }, { "start_pos": 327, "end_pos": 329, "annotation": "n_glycosylation_sequon" }, { "start_pos": 349, "end_pos": 351, "annotation": "n_glycosylation_sequon" }, { "start_pos": 383, "end_pos": 385, "annotation": "n_glycosylation_sequon" }, { "start_pos": 454, "end_pos": 456, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1A9S0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9S0" }, { "id": "PS50003", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50003" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PH", "eco_id": "ECO_0000259", "start_pos": 359, "end_pos": 454, "start_aa": "Asn", "end_aa": "Asn", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 151, "end_pos": 153 }, { "start_pos": 222, "end_pos": 224 }, { "start_pos": 248, "end_pos": 250 }, { "start_pos": 327, "end_pos": 329 }, { "start_pos": 349, "end_pos": 351 }, { "start_pos": 383, "end_pos": 385 }, { "start_pos": 454, "end_pos": 456 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A7K2-1", "uniprot_ac": "A0A8V1A7K2", "uniprot_id": "A0A8V1A7K2_CHICK", "mass": { "chemical_mass": 52533.0, "monoisotopic_mass": 52533.0 }, "refseq": { "ac": "XP_040529232", "name": "F-box only protein 3 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040529232" }, "gene_names": [ { "name": "FBXO3", "type": "recommended", "evidence": [ { "id": "A0A8V1A7K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7K2" } ] }, { "name": "FBXO3", "type": "synonym", "evidence": [ { "id": "XP_040529232", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040529232" } ] } ], "protein_names": [ { "name": "F-box only protein 3", "type": "recommended", "evidence": [ { "id": "A0A8V1A7K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7K2/entry#names_and_taxonomy" } ] }, { "name": "F-box only protein 3 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_040529232", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040529232" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052577.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040529232", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040529232" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7K2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7K2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FBXO3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7K2", "locus": { "chromosome": "5", "start_pos": 17929457, "end_pos": 17949011, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010024818", "url": "https://www.ensembl.org/id/ENSGALG00010024818" } ] } } ], "crossref": [ { "id": "A0A8V1A7K2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A7K2", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd22084", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22084", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "429495", "url": "https://www.ncbi.nlm.nih.gov/gene/429495", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001810", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001810", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007474", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007474", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018958", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018958", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036047", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036047", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036767", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036767", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037883", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037883", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052121", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052121", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A2B5", "url": "https://www.orthodb.org/?gene=A0A8V1A2B5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A7K2", "url": "https://www.orthodb.org/?gene=A0A8V1A7K2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46550", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46550", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46550:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46550:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04379", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04379", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF09346", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09346", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12937", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12937", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040529232", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040529232", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1A2B5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2B5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A2B5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2B5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A7K2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7K2", "database": "UniProtKB", "categories": [ "Protein" ] }, { 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"MEAKHLTMGCCYLSRRLNQLSSHDPLWKRHCKKYWLISDEEKIRRNQSWKAIFVSTYSDLGRYIQYYATLKKAWDDLEKYLGQRCPRMIGSLKESVQEEDLDAVEAQIGCKLPDDYRCSFRIHNGQKLVVPGLMGSMALSNHYRSEDLLDIDTAAGGFQQRLGLKQCLPLTFCIHTGLSQYMALESVEGRNKYEIFYQCPDQMARNPSAIDMFITGTSYLEWFTSYVNKVVTGGYPIIRDQIFRYVHDKECVATTGDITVSVSTSFLPELSSVHPPHYFFTYRIRIEMSKDALPEKACQLDSRYWRITNAKGDVEEVQGPGVVGEFPIISPGRVYEYTSCTTFSTTSGYMEGYYTFHCLYYKEKFFNVTIPRFHMVCPTFKVSTARMETNHNEYAVDEDEDSTDTDEYEDRRRVMDIPAPSGRCPHHT", "length": 428, "header": "tr|A0A8V1A2B5-1|A0A8V1A7K2_CHICK Computationally mapped isoform of F-box only protein 3 OS=Gallus gallus OX=9031 GN=FBXO3 PE=1 SV=1 CANONICAL=A0A8V1A7K2-1" }, "locus": { "chromosome": "5", "start_pos": 17947784, "end_pos": 17930443, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010060580.1", "url": "https://www.ensembl.org/id/ENSGALT00010060580.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010037339.1", "url": "https://www.ensembl.org/id/ENSGALP00010037339.1" } ] } }, { "isoform_ac": 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"id": "ENSGALP00010037341.1", "url": "https://www.ensembl.org/id/ENSGALP00010037341.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7K2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7K2" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7K2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7K2" } ], "pmid": "" }, { "name": "SCF ubiquitin ligase complex", "id": "GO:0019005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019005", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7K2", "url": 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"pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 394, "end_pos": 396, "annotation": "n_glycosylation_sequon" }, { "start_pos": 73, "end_pos": 75, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1A7K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7K2" }, { "id": "PS51087", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51087" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "ApaG", "eco_id": "ECO_0000259", "start_pos": 279, "end_pos": 409, "start_aa": "Val", "end_aa": "Val", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1A7K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7K2" }, { "id": "PS50181", "database": "PROSITE", "url": 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"OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ACW6", "url": "https://www.orthodb.org/?gene=A0A8V1ACW6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AEY8", "url": "https://www.orthodb.org/?gene=A0A8V1AEY8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21555", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21555", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21555:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21555:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15385", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15385", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1A2H0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2H0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A2H0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2H0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A7H2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7H2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A7H2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7H2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ACW6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACW6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ACW6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACW6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AEY8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEY8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AEY8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEY8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMLEMQQKLNRISLCSFQSCDVNGRTRRDTAIPRQIKAHLQFLSVLFFFFPFSSQSDNSYDYLSVEEKECLMFLEETIGSLDAGADSGVSTDETDYAEASRLPRARLKRDSAPQDLENRAPPGSTAQQHAADQKGTEGSSSFPSSAPATAPNPGYHSLPRNITAANAHLANRADGKTDTHTMQDPVLPGKSPQELGKEGRLSQANMRREVRSLIIPPPAPFQDNQESRAEQPQSNSSDARKENTEESWTQPRPALGMVAVPGPTALPHREIGRESAVLPQGQQEHPAAQEVPQDPNTKRGPPTAPKPRKLPPNIILRTSKPSSVPLGAEPGHKVKVPPPSPAGSAGDTAAEKQNSGQLDPKEREKARREALEKLGLPQDLQEPCARPGPVPPPCDQARAAPSTAPAGRAMNFKSNTLERSGVGLGSCMAKEPGVKGSGSLGKMSFIERLAPSFLRSSRPRPASLGAGKDFAALKEPIEVEKSSKRRSSPLPSFPQPPRSCVSVKISPKGSTEEHRREALRKLGLLKE", "length": 527, "header": "tr|A0A8V1A7H2-1|A0A8V1A7H2_CHICK Isoform 1 of Chromosome 1 open reading frame 116 OS=Gallus gallus OX=9031 GN=C1orf116 PE=1 SV=1 CANONICAL=A0A8V1A7H2-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A2H0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7H2/entry#A0A8V1A2H0-1", "sequence": { "sequence": "MIEKQLSSCAVPARTAARDMPGKDLGLGMAACNSDSCDSMVSTTSNHSQRSDNSYDYLSVEEKECLMFLEETIGSLDAGADSGVSTDETDYAEASRLPRARLKRDSAPQDLENRAPPGSTAQQHAADQKGTEGSSSFPSSAPATAPNPGYHSLPRNITAANAHLANRADGKTDTHTMQDPVLPGKSPQELGKEGRLSQANMRREVRSLIIPPPAPFQDNQESRAEQPQSNSSDARKENTEESWTQPRPALGMVAVPGPTALPHREIGRESAVLPQGQQEHPAAQEVPQDPNTKRGPPTAPKPRKLPPNIILRTSKPSSVPLGAEPGHKVKVPPPSPAGSAGDTAAEKQNSGQLDPKEREKARREALEKLGLPQDLQEPCARPGPVPPPCDQARAAPSTAPAGRAMNFKSNTLERSGVGLGSCMAKEPGVKGSGSLGKMSFIERLAPSFLRSSRPRPASLGAGKDFAALKEPIEVEKSSKRRSSPLPSFPQPPRSCVSVKISPKGSTEEHRREALRKLGLLKE", "length": 522, "header": "tr|A0A8V1A2H0-1|A0A8V1A7H2_CHICK Computationally mapped isoform of Chromosome 1 open reading frame 116 OS=Gallus gallus OX=9031 GN=C1orf116 PE=1 SV=1 CANONICAL=A0A8V1A7H2-1" }, "locus": { "chromosome": "26", "start_pos": 2645643, "end_pos": 2641136, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065819.1", "url": "https://www.ensembl.org/id/ENSGALT00010065819.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040085.1", "url": "https://www.ensembl.org/id/ENSGALP00010040085.1" } ] } }, { "isoform_ac": "A0A8V1A7H2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7H2/entry#A0A8V1A7H2-1", "sequence": { "sequence": "MMLEMQQKLNRISLCSFQSCDVNGRTRRDTAIPRQIKAHLQFLSVLFFFFPFSSQSDNSYDYLSVEEKECLMFLEETIGSLDAGADSGVSTDETDYAEASRLPRARLKRDSAPQDLENRAPPGSTAQQHAADQKGTEGSSSFPSSAPATAPNPGYHSLPRNITAANAHLANRADGKTDTHTMQDPVLPGKSPQELGKEGRLSQANMRREVRSLIIPPPAPFQDNQESRAEQPQSNSSDARKENTEESWTQPRPALGMVAVPGPTALPHREIGRESAVLPQGQQEHPAAQEVPQDPNTKRGPPTAPKPRKLPPNIILRTSKPSSVPLGAEPGHKVKVPPPSPAGSAGDTAAEKQNSGQLDPKEREKARREALEKLGLPQDLQEPCARPGPVPPPCDQARAAPSTAPAGRAMNFKSNTLERSGVGLGSCMAKEPGVKGSGSLGKMSFIERLAPSFLRSSRPRPASLGAGKDFAALKEPIEVEKSSKRRSSPLPSFPQPPRSCVSVKISPKGSTEEHRREALRKLGLLKE", "length": 527, "header": "tr|A0A8V1A7H2-1|A0A8V1A7H2_CHICK Isoform 1 of Chromosome 1 open reading frame 116 OS=Gallus gallus OX=9031 GN=C1orf116 PE=1 SV=1 CANONICAL=A0A8V1A7H2-1" }, "locus": { "chromosome": "26", "start_pos": 2643079, "end_pos": 2641136, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065816.1", "url": "https://www.ensembl.org/id/ENSGALT00010065816.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040082.1", "url": "https://www.ensembl.org/id/ENSGALP00010040082.1" } ] } }, { "isoform_ac": "A0A8V1ACW6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7H2/entry#A0A8V1ACW6-1", "sequence": { "sequence": "MLCAVPARTAARDMPGKDLGLGMAACNSDSCDSMVSTTSNHSQRSDNSYDYLSVEEKECLMFLEETIGSLDAGADSGVSTDETDYAEASRLPRARLKRDSAPQDLENRAPPGSTAQQHAADQKGTEGSSSFPSSAPATAPNPGYHSLPRNITAANAHLANRADGKTDTHTMQDPVLPGKSPQELGKEGRLSQANMRREVRSLIIPPPAPFQDNQESRAEQPQSNSSDARKENTEESWTQPRPALGMVAVPGPTALPHREIGRESAVLPQGQQEHPAAQEVPQDPNTKRGPPTAPKPRKLPPNIILRTSKPSSVPLGAEPGHKVKVPPPSPAGSAGDTAAEKQNSGQLDPKEREKARREALEKLGLPQDLQEPCARPGPVPPPCDQARAAPSTAPAGRAMNFKSNTLERSGVGLGSCMAKEPGVKGSGSLGKMSFIERLAPSFLRSSRPRPASLGAGKDFAALKEPIEVEKSSKRRSSPLPSFPQPPRSCVSVKISPKGSTEEHRREALRKLGLLKE", "length": 516, "header": "tr|A0A8V1ACW6-1|A0A8V1ACW6_CHICK Computationally mapped isoform of Chromosome 1 open reading frame 116 OS=Gallus gallus OX=9031 GN=C1orf116 PE=1 SV=1 CANONICAL=A0A8V1A7H2-1" }, "locus": { "chromosome": "26", "start_pos": 2644417, "end_pos": 2641136, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065817.1", "url": "https://www.ensembl.org/id/ENSGALT00010065817.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040083.1", "url": "https://www.ensembl.org/id/ENSGALP00010040083.1" } ] } }, { "isoform_ac": "A0A8V1AEY8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7H2/entry#A0A8V1AEY8-1", "sequence": { "sequence": "MPGKDLGLGMAACNSDSCDSMVSTTSNHSQRSDNSYDYLSVEEKECLMFLEETIGSLDAGADSGVSTDETDYAEASRLPRARLKRDSAPQDLENRAPPGSTAQQHAADQKGTEGSSSFPSSAPATAPNPGYHSLPRNITAANAHLANRADGKTDTHTMQDPVLPGKSPQELGKEGRLSQANMRREVRSLIIPPPAPFQDNQESRAEQPQSNSSDARKENTEESWTQPRPALGMVAVPGPTALPHREIGRESAVLPQGQQEHPAAQEVPQDPNTKRGPPTAPKPRKLPPNIILRTSKPSSVPLGAEPGHKVKVPPPSPAGSAGDTAAEKQNSGQLDPKEREKARREALEKLGLPQDLQEPCARPGPVPPPCDQARAAPSTAPAGRAMNFKSNTLERSGVGLGSCMAKEPGVKGSGSLGKMSFIERLAPSFLRSSRPRPASLGAGKDFAALKEPIEVEKSSKRRSSPLPSFPQPPRSCVSVKISPKGSTEEHRREALRKLGLLKE", "length": 503, "header": "tr|A0A8V1AEY8-1|A0A8V1AEY8_CHICK Computationally mapped isoform of Chromosome 1 open reading frame 116 OS=Gallus gallus OX=9031 GN=C1orf116 PE=1 SV=1 CANONICAL=A0A8V1A7H2-1" }, "locus": { "chromosome": "26", "start_pos": 2643939, "end_pos": 2641136, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065820.1", "url": "https://www.ensembl.org/id/ENSGALT00010065820.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040086.1", "url": "https://www.ensembl.org/id/ENSGALP00010040086.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 264, "start_aa": "Thr", "end_pos": 264, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr264", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:419849", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419849", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287AN31-1", "protein_name": "Chromosome 9 C1orf116 homolog", "gene_name": "C1orf116", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPERELWPAGPGSEPVTRVSSCDSMMSTTSTRSGSSDSSYDFLSAEEKECLLFLEETIGSLDTEADSGLSTDESEQPVTPRGPRALPTAQPAPQGHPEETTVRQGPVPRRVTLSSSSHPPEPQSLGLRSGSYSLPRNIHISQNQNLRKGTTQTNSRIPRGSKGLVPGPEKEQVSESSEPHQAPASPQDAALDLDGPLIPPPEAFRDTQPQQCGQGNLARRPGVLRHTPQLPTSLGPQKKGDTASEAMSQKANEKGSTRGPGQPRSPPPVFSQNARAEDAPVPSWGDPNTQLAPVTAPKPRKLPPNIVLKSSRSSFHSDPQNRLSRHSEAAPGDSGPAPSSLQEQRKARREALEKLGLPQDQDEPSPHLSRPSVRLKETRAPAPSPAPAQVSAAMPAAGKALAPASTQGPSLGKAPVPAQQSSPGKVLIPAQEPTSGKVPAAKSMPIPIPKAPRANSPLTQRKPDSGLTLQESSIPGLRQMNFKSNTLERSGVGLSSYLSAEKEPSPQTSASLGKSSFLDRIPPNVLRNSRPRPASLGRKDFEGIQVGKLADLEQEQSSKRLSYQGQSRDKLPRPACVSVKISPKGVSDEHRREALKKLGLLKE", "length": 603 }, "evidence": [ { "id": "A0A8V1A7H2", "url": "https://omabrowser.org/oma/group/A0A8V1A7H2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A5D7K1-1", "protein_name": "Specifically androgen-regulated gene protein", "gene_name": "SARG", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPERELWPAGPGLEPATRVGSCDSMMSTTSTRSGSSDSSYDFLSAEEKECLLFLEETIGSLDTEADSGLSTEKSEQATTPQVPRALPKTQPAPQGHPEEITGRVPEPKRVTPFSSAHPPGPQSLGLRSGSYSLPRNIHIGRNQNLRKSTTLTNSHNPGGSEGLVSGPETEQVSQSREPRQTLATPPDAALELDGALIPPPEAFRDTQPQQRGQGSLPRGPGELSPRPQVHPSLSSQRNREPAPEAMSQKASEKGSTGEPVPPRPPPLVSSRDAGSGDAAVLSGGHPSARPAPLTAPKPRKLPPNIVLKSSRSSFHSDPQNRLSRHSEAAPGDPSPASSSLQEQRKARREALEKLGLPQDQEEPSPRLSRPSVRLKETGVQAVSPAPAQVPGRAPAAAPTQGPSPGKAPALAQPPSPGKVLVPAQESTPGTAPAAKSTPIPIPKGPRAHSPLTQRKPDSGLTLQESGVPGLRQMSFKSNTLERSGIGLSSYLSAEKASSPQTSTSLEKGSFLDRISPSVLRNSRPRPASLGTGKDFEGIQVGKLADLEQEGGPKRLSFQGQSRDKLPRPPCVSVRISPKGVSDEHRREALKKLGLLKE", "length": 597 }, "evidence": [ { "id": "A0A8V1A7H2", "url": "https://omabrowser.org/oma/group/A0A8V1A7H2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q499V8-1", "protein_name": "Specifically androgen-regulated gene protein", "gene_name": "Sarg", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPKRELWPAGSCSEPVTHIGSCGSMMSTTSTHSGSSDSSYDFLSAEEKECLLFLEKTIGSLEAEADSGLSTDESEPATSPQSFRALPTTTQRAPQGKPEARDTQQVPVPVPKRAAQSSGPPESPSPGLRSGSYSLPRNLHLGRSQNLRKSATQTNSVSEAPEVFLEEPKKGQTRQGAKTIQPPAPSQEGTPDLNTVLIPPPEAFQDITSKKAEGESPPKKPGEQTHRPQGHILERSPHSQKKADMSSETMTHKATEKGWTEGPQRPQQPPTQPSQNTQAEEPSLPSGVKPNIQQSLLTATKPRRLPPNIVLKSSRSSFHSHPQNWLSNHTEATDSGPVSSLQEQRKARREALEKLGLPQDQDDPSLPVNKHTGSFKVKEAQAQTSSQARAPAQPASPALVRGTASVAEKASSVKAITPLDSLSKGWIPAQETPPGKVGAAKSMPIPIPKASKENSSLTQSKPDPRLTLQESSIPGLRQMNFKSNTLERSGVGLSSYLSAAEKDPGGQTSTSLGKSPFLDKVSSSVFRNSRPRPASLGMGKDFAGIQGGKLVGLEQGQCSQQPSFKGQSHDKLPRPPCVSVKISPKGIPDGHRREALKKLGLLKE", "length": 604 }, "evidence": [ { "id": "A0A8V1A7H2", "url": "https://omabrowser.org/oma/group/A0A8V1A7H2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8BI29-1", "protein_name": "Specifically androgen-regulated gene protein", "gene_name": "Sarg", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKRELWPAGLCSEPVTHIGSCGDMMSTTSTRSGSSDSSYDFLSAEEKECLLFLEKTIGSLEAEADSGLSTDESEPATSPRSFRALPTATQQAPQGKPEATDIQQVPVPKRVAQPSCPPESHSLGLRAGSYSLPRNLHLGRSQNLRESATQANSPVSEASEVFLEEPEKGQTSQGAKAKTIQPPAPSQKGTLDLSTVLIPPPEAFQDIRPKESGEESPPKKPGEQTHTPQVHSLERSPHSQKKVEMSSETVSHKATEKGWTEGLQQPQQPPAQSSQPTKAEELSLPSGVKPSIQQTPLTASKARKLPPNIVLKSSRSSFHSHPQNWLSNHTEATDSGPVSSLQEQRKARREALEKLGLPQDQDDPSLLVNKHTSTLKVREAQPQTPSQARAPARPASPALVSGTASAAGKVSPKKAVAPMDSLSKGWIPTQETPPGKVAEAKSMPIPIPKTLKENSSRTQPKPDPRLTLQESSIPGLRQMNFKSNTLERSGVGLSSYLSAAEKKDPSCQTSTSLGKSPFLDKVSPSAFRNSRPRPASLGMGKDFAGIQGGKLVGLEQDQCSQQPSFKGQSYDKLPRPPCISVKISPKGIPDGHRREALKKLGLLKE", "length": 606 }, "evidence": [ { "id": "A0A8V1A7H2", "url": "https://omabrowser.org/oma/group/A0A8V1A7H2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9BW04-1", "protein_name": "Specifically androgen-regulated gene protein", "gene_name": "SARG", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPERELWPAGTGSEPVTRVGSCDSMMSSTSTRSGSSDSSYDFLSTEEKECLLFLEETIGSLDTEADSGLSTDESEPATTPRGFRALPITQPTPRGGPEETITQQGRTPRTVTESSSSHPPEPQGLGLRSGSYSLPRNIHIARSQNFRKSTTQASSHNPGEPGRLAPEPEKEQVSQSSQPRQAPASPQEAALDLDVVLIPPPEAFRDTQPEQCREASLPEGPGQQGHTPQLHTPSSSQEREQTPSEAMSQKAKETVSTRYTQPQPPPAGLPQNARAEDAPLSSGEDPNSRLAPLTTPKPRKLPPNIVLKSSRSSFHSDPQHWLSRHTEAAPGDSGLISCSLQEQRKARKEALEKLGLPQDQDEPGLHLSKPTSSIRPKETRAQHLSPAPGLAQPAAPAQASAAIPAAGKALAQAPAPAPGPAQGPLPMKSPAPGNVAASKSMPISIPKAPRANSALTPPKPESGLTLQESNTPGLRQMNFKSNTLERSGVGLSSYLSTEKDASPKTSTSLGKGSFLDKISPSVLRNSRPRPASLGTGKDFAGIQVGKLADLEQEQSSKRLSYQGQSRDKLPRPPCVSVKISPKGVPNEHRREALKKLGLLKE", "length": 601 }, "evidence": [ { "id": "A0A8V1A7H2", "url": "https://omabrowser.org/oma/group/A0A8V1A7H2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7H2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7H2" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7H2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7H2" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7H2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7H2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 161, "end_pos": 163, "annotation": "n_glycosylation_sequon" }, { "start_pos": 235, "end_pos": 237, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 264 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 161, "end_pos": 163 }, { "start_pos": 235, "end_pos": 237 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A7L6-1", "uniprot_ac": "A0A8V1A7L6", "uniprot_id": "A0A8V1A7L6_CHICK", "mass": { "chemical_mass": 236432.0, "monoisotopic_mass": 236432.0 }, "refseq": {}, "gene_names": [ { "name": "CR1", "type": "recommended", "evidence": [ { "id": "A0A8V1A7L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7L6" } ] } ], "protein_names": [ { "name": "Complement C3b/C4b receptor 1 (Knops blood group)", "type": "synonym", "evidence": [ { "id": "A0A8V1A7L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7L6/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "This protein recognizes C4b and C3b fragments that condense with cell-surface hydroxyl or amino groups when nascent C4b and C3b are locally generated during C4 and c3 activation. Interaction of daf with cell-associated C4b and C3b polypeptides interferes with their ability to catalyze the conversion of C2 and factor B to enzymatically active C2a and Bb and thereby prevents the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade. Inhibits complement activation by destabilizing and preventing the formation of C3 and C5 convertases, which prevents complement damage.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7L6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7L6#function" }, { "database": "UniProtKB", "id": "ARBA00045541", "url": "https://www.uniprot.org/uniprotkb/ARBA00045541#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7L6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7L6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CR1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7L6", "locus": {} } ], "crossref": [ { "id": "cd00033", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00033", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000436", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000436", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035976", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035976", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050350", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050350", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR19325", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19325", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19325:SF317", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19325:SF317", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19325:SF551", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19325:SF551", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00084", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00084", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1A2L5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2L5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A2L5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2L5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A7L6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7L6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A7L6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7L6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVPGEEPCPLPITRDALQWLYPAESPLCLLCHRYPVSHSRSQWPILPRTVGPKYHQQKLTGAAQPKLVAAPTLCWSPQVPVPQPGKPHSCDPSSGIGNQDPYICFASPRICSLHWDQSMVLAFTLSILGCSTLLLAAASKQQVRQHRCPVPHIKNGRRAPSRYVFWPGDAARFTCNAGYTLQGSHISVCQADFSWSPPLPACKKGVMCPQPPNIANGLHSGQSMDKVLPGAVVNYSCKDGFELVGNVSISCSEAGRWSRPLPRCQAIGCQSPTVHNGKLQAPKDTYEAGEMLWFDCNPGYAVEGSHWAQCQPGGSWDPPVLRCERVQPCPVPPRISNGDHDGHGTAEFTMGMYVTYTCNLGYYLAGNVERVFCKASGKWSQPSPRCEEVTCPQPPNIANGLHSGRSSARFRYGTVVYYSCKDGFELVGNVSTSCSEVGRWSRPLPRCQAIGCQSPTVHNGKLQAPRDTYEAGEMLQFDCNPGYAAEGSHRARCQPGGSWDPPVLRCQRVRPCPMPPKISNGDHNRHGEAFFTAGMSVTYSCDPTFYLVGNAHVVCRASGTWSQPSPRCEATICLKPDIQDGWIVDDQGLIYAPGQMVTFKCQEGYSLQGSAKALCQENGSWDPPVPLCEPLHSPTLPRRADRSGGCGVPTRLTFAELNEEHRNEIDFSVGKTVGYTCRPGFAKHPGMSPTITCLQGGVWSEALEFCKRKQCNHPGEPENGRITALADLFFGSTVVYSCEEGHRLIGQSSRRCEISGGRVAWTGDIPICQRIPCEPPPNIPHGKHTGRLLDEFLYGTSITYSCEPGYPLRGAASIFCTTHDGKNGVWSGPPPLCGEAGCSAPQIQNGRIVPAPRSTYAHKDTVTFECEPGYVIRGPKVVQCQQNNTWQPPVPTCEQAGCRAPPRLVFAELKEPYRNQTAFPVGGTVEYTCQPGYARHVGMSPTITCLGNQSWSVALEFCKRKQCENPEDPQNGRAVVLTDLLLGSKVNYTCDEGYKLIGHSQRTCEVSGTHVAWSGDAPICHRIVCDPPPDIPHGTHSGGLMDVFPYMTVVTYTCEPGRVLAGTASIFCTTVDGKRGAWSGPPPRCGEVQCPPPPSIANGKHSSQPSDTFLPGAAVQYTCKDGYMLTGNASITCTAAGTWSWPQPRCEVVQCPSPPNITHGQYSSEDVRVFIPGTSVRYKCEPGYVLTGKTALTCLTSGVWSIPYPQCKAVTCMSPSIKHGEVAEGQQAVYHPGTIITIRCHPGYMLRGSQEPKCHSDGRWVPSVPSCEPALPCPPPPTIAHGIHDAELGANFTSGMSVNYSCQPGFSLLGDPSIQCMEGSWSLPYPRCAVGCGTPTVLQFAELSKEYKNWTEFPVGTTVKYTCQPGYARHSQTPPTITCLKNQTWSEAKKFCRRRRCDHPGEPENGRLIVTTDLLFGSTVNYTCEEGYRLVGASQRHCVVSGSGTRVTWTGDVPTCQSIVCDPPPDIPHGMHSGHSMDAFPYAAVVTYMCEPGHVLAGTASIFCTTVDGEHGAWSGPPPHCGGELCPSPPVIDHGQHDGKDVDFIPGMSVNYSCDPGYSLTGKAALYCTDNASWSSPQPRCEVLQCPSPPNIDGGNHSSQDVEVFFPGMAVNYSCDPGYSLLGEGSIYCTESGNWSLPTPQCEGSCGAPPTLSYAELAKEHQNMTAFPVGSTVRYACRPGFMRHPTVLPALTCLKNHTWSDVRAFCKRKECNYPEAPQNGRVVVLTDLLFRSIVNYTCEEGYRLVGQSLRRCELSGADIAWSGDAPTCQKVVCPVPQIQNGRVSIPKQRYRYKDTVSFQCHEGFVLKGHSMAQCKADKTWDPPVPICEQVVKCLPPPSIINGEHSHFSDTFGVGAIVHYRCKPGFFLTGNESIRCTPHGVWSRPLPQCEAGCVSPGIGHGKVIGWEPLYMPGNIITIECNTDNISKVLHKSQCRPGGTWFPPLPACDGVLHCSKPPDILHGGHSGLGKAVFTPGTSVNYSCETGFSLIGMASIYCTESGAWSHPSPVCQVVKCLHPPAITNGKLQGNTSDTFFYGVSVSYSCDSGYSLTGDAFITCTASGTWSPPPQCKEISCVFPEVQGVKKTTAGKTYRFGTNITLECDDGYTLEGLSQIQCQENFSWDPPVPACKLTSPRSGSVGLGIAAAVVLLLLGVTIGWKIISKKKEGYYRTYENYNYKTSLD", "length": 2180, "header": "tr|A0A8V1A7L6-1|A0A8V1A7L6_CHICK Isoform 1 of Complement C3b/C4b receptor 1 (Knops blood group) OS=Gallus gallus OX=9031 GN=CR1 PE=3 SV=1 CANONICAL=A0A8V1A7L6-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A2L5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7L6/entry#A0A8V1A2L5-1", "sequence": { "sequence": "MVLAFTLSILGCSTLLLAAASKQQVRQHRCPVPHIKNGRRAPSRYVFWPGDAARFTCNAGYTLQGSHISVCQADFSWSPPLPACKKGVMCPQPPNIANGLHSGQSMDKVLPGAVVNYSCKDGFELVGNVSISCSEAGRWSRPLPRCQAIGCQSPTVHNGKLQAPKDTYEAGEMLWFDCNPGYAVEGSHWAQCQPGGSWDPPVLRCERVQPCPVPPRISNGDHDGHGTAEFTMGMYVTYTCNLGYYLAGNVERVFCKASGKWSQPSPRCEEVTCPQPPNIANGLHSGRSSARFRYGTVVYYSCKDGFELVGNVSTSCSEVGRWSRPLPRCQAIGCQSPTVHNGKLQAPRDTYEAGEMLQFDCNPGYAAEGSHRARCQPGGSWDPPVLRCQRVRPCPMPPKISNGDHNRHGEAFFTAGMSVTYSCDPTFYLVGNAHVVCRASGTWSQPSPRCEATICLKPDIQDGWIVDDQGLIYAPGQMVTFKCQEGYSLQGSAKALCQENGSWDPPVPLCEPLHSPTLPRRADRSGGCGVPTRLTFAELNEEHRNEIDFSVGKTVGYTCRPGFAKHPGMSPTITCLQGGVWSEALEFCKRKECNYPEAPQNGRVVVLTDLLFRSIVNYTCEEGYRLVGQSLRRCELSGADIAWSGDAPTCQKVVCPVPQIQNGRVSIPKQRYRYKDTVSFQCHEGFVLKGHSMAQCKADKTWDPPVPICEQVVKCLPPPSIINGEHSHFSDTFGVGAIVHYRCKPGFFLTGNESIRCTPHGVWSRPLPQCEAGCVSPGIGHGKVIGWEPLYMPGNIITIECNTDNISKVLHKSQCRPGGTWFPPLPACDGVLHCSKPPDILHGGHSGLGKAVFTPGTSVNYSCETGFSLIGMASIYCTESGAWSHPSPVCQVVKCLHPPAITNGKLQGNTSDTFFYGVSVSYSCDSGYSLTGDAFITCTASGTWSPPPQCKEISCVFPEVQGVKKTTAGKTYRFGTNITLECDDGYTLEGLSQIQCQENFSWDPPVPACKLTSPRSGSVGLGIAAAVVLLLLGVTIGWKIISKKKEGYYRTYENYNYKTSLD", "length": 1062, "header": "tr|A0A8V1A2L5-1|A0A8V1A7L6_CHICK Computationally mapped isoform of Complement C3b/C4b receptor 1 (Knops blood group) OS=Gallus gallus OX=9031 GN=CR1 PE=3 SV=1 CANONICAL=A0A8V1A7L6-1" }, "locus": { "chromosome": "26", "start_pos": 2721519, "end_pos": 2701479, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065859.1", "url": "https://www.ensembl.org/id/ENSGALT00010065859.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040125.1", "url": "https://www.ensembl.org/id/ENSGALP00010040125.1" } ] } }, { "isoform_ac": "A0A8V1A7L6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7L6/entry#A0A8V1A7L6-1", "sequence": { "sequence": "MVPGEEPCPLPITRDALQWLYPAESPLCLLCHRYPVSHSRSQWPILPRTVGPKYHQQKLTGAAQPKLVAAPTLCWSPQVPVPQPGKPHSCDPSSGIGNQDPYICFASPRICSLHWDQSMVLAFTLSILGCSTLLLAAASKQQVRQHRCPVPHIKNGRRAPSRYVFWPGDAARFTCNAGYTLQGSHISVCQADFSWSPPLPACKKGVMCPQPPNIANGLHSGQSMDKVLPGAVVNYSCKDGFELVGNVSISCSEAGRWSRPLPRCQAIGCQSPTVHNGKLQAPKDTYEAGEMLWFDCNPGYAVEGSHWAQCQPGGSWDPPVLRCERVQPCPVPPRISNGDHDGHGTAEFTMGMYVTYTCNLGYYLAGNVERVFCKASGKWSQPSPRCEEVTCPQPPNIANGLHSGRSSARFRYGTVVYYSCKDGFELVGNVSTSCSEVGRWSRPLPRCQAIGCQSPTVHNGKLQAPRDTYEAGEMLQFDCNPGYAAEGSHRARCQPGGSWDPPVLRCQRVRPCPMPPKISNGDHNRHGEAFFTAGMSVTYSCDPTFYLVGNAHVVCRASGTWSQPSPRCEATICLKPDIQDGWIVDDQGLIYAPGQMVTFKCQEGYSLQGSAKALCQENGSWDPPVPLCEPLHSPTLPRRADRSGGCGVPTRLTFAELNEEHRNEIDFSVGKTVGYTCRPGFAKHPGMSPTITCLQGGVWSEALEFCKRKQCNHPGEPENGRITALADLFFGSTVVYSCEEGHRLIGQSSRRCEISGGRVAWTGDIPICQRIPCEPPPNIPHGKHTGRLLDEFLYGTSITYSCEPGYPLRGAASIFCTTHDGKNGVWSGPPPLCGEAGCSAPQIQNGRIVPAPRSTYAHKDTVTFECEPGYVIRGPKVVQCQQNNTWQPPVPTCEQAGCRAPPRLVFAELKEPYRNQTAFPVGGTVEYTCQPGYARHVGMSPTITCLGNQSWSVALEFCKRKQCENPEDPQNGRAVVLTDLLLGSKVNYTCDEGYKLIGHSQRTCEVSGTHVAWSGDAPICHRIVCDPPPDIPHGTHSGGLMDVFPYMTVVTYTCEPGRVLAGTASIFCTTVDGKRGAWSGPPPRCGEVQCPPPPSIANGKHSSQPSDTFLPGAAVQYTCKDGYMLTGNASITCTAAGTWSWPQPRCEVVQCPSPPNITHGQYSSEDVRVFIPGTSVRYKCEPGYVLTGKTALTCLTSGVWSIPYPQCKAVTCMSPSIKHGEVAEGQQAVYHPGTIITIRCHPGYMLRGSQEPKCHSDGRWVPSVPSCEPALPCPPPPTIAHGIHDAELGANFTSGMSVNYSCQPGFSLLGDPSIQCMEGSWSLPYPRCAVGCGTPTVLQFAELSKEYKNWTEFPVGTTVKYTCQPGYARHSQTPPTITCLKNQTWSEAKKFCRRRRCDHPGEPENGRLIVTTDLLFGSTVNYTCEEGYRLVGASQRHCVVSGSGTRVTWTGDVPTCQSIVCDPPPDIPHGMHSGHSMDAFPYAAVVTYMCEPGHVLAGTASIFCTTVDGEHGAWSGPPPHCGGELCPSPPVIDHGQHDGKDVDFIPGMSVNYSCDPGYSLTGKAALYCTDNASWSSPQPRCEVLQCPSPPNIDGGNHSSQDVEVFFPGMAVNYSCDPGYSLLGEGSIYCTESGNWSLPTPQCEGSCGAPPTLSYAELAKEHQNMTAFPVGSTVRYACRPGFMRHPTVLPALTCLKNHTWSDVRAFCKRKECNYPEAPQNGRVVVLTDLLFRSIVNYTCEEGYRLVGQSLRRCELSGADIAWSGDAPTCQKVVCPVPQIQNGRVSIPKQRYRYKDTVSFQCHEGFVLKGHSMAQCKADKTWDPPVPICEQVVKCLPPPSIINGEHSHFSDTFGVGAIVHYRCKPGFFLTGNESIRCTPHGVWSRPLPQCEAGCVSPGIGHGKVIGWEPLYMPGNIITIECNTDNISKVLHKSQCRPGGTWFPPLPACDGVLHCSKPPDILHGGHSGLGKAVFTPGTSVNYSCETGFSLIGMASIYCTESGAWSHPSPVCQVVKCLHPPAITNGKLQGNTSDTFFYGVSVSYSCDSGYSLTGDAFITCTASGTWSPPPQCKEISCVFPEVQGVKKTTAGKTYRFGTNITLECDDGYTLEGLSQIQCQENFSWDPPVPACKLTSPRSGSVGLGIAAAVVLLLLGVTIGWKIISKKKEGYYRTYENYNYKTSLD", "length": 2180, "header": "tr|A0A8V1A7L6-1|A0A8V1A7L6_CHICK Isoform 1 of Complement C3b/C4b receptor 1 (Knops blood group) OS=Gallus gallus OX=9031 GN=CR1 PE=3 SV=1 CANONICAL=A0A8V1A7L6-1" }, "locus": { "chromosome": "26", "start_pos": 2721519, "end_pos": 2701125, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065861.1", "url": "https://www.ensembl.org/id/ENSGALT00010065861.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040127.1", "url": "https://www.ensembl.org/id/ENSGALP00010040127.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1278, "start_aa": "Thr", "end_pos": 1278, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1278", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7L6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7L6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7L6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7L6" } ], "pmid": "" }, { "name": "complement activation, classical pathway", "id": "GO:0006958", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006958", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7L6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7L6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1128, "end_pos": 1130, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1156, "end_pos": 1158, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1291, "end_pos": 1293, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1299, "end_pos": 1301, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1349, "end_pos": 1351, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1382, "end_pos": 1384, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1421, "end_pos": 1423, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1551, "end_pos": 1553, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1571, "end_pos": 1573, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1596, "end_pos": 1598, 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"n_glycosylation_sequon" }, { "start_pos": 49, "end_pos": 51, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 260, "end_pos": 262 }, { "start_pos": 303, "end_pos": 305 }, { "start_pos": 49, "end_pos": 51 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": 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"n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A7G6-1", "uniprot_ac": "A0A8V1A7G6", "uniprot_id": "A0A8V1A7G6_CHICK", "mass": { "chemical_mass": 42437.0, "monoisotopic_mass": 42437.0 }, "refseq": { "ac": "XP_024999341", "name": "protein mab-21-like 3 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024999341" }, "gene_names": [ { "name": "MAB21L3", "type": "recommended", "evidence": [ { "id": "A0A8V1A7G6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7G6" } ] }, { "name": "MAB21L3", "type": "synonym", "evidence": [ { "id": "XP_024999341", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024999341" } ] } ], "protein_names": [ { "name": "Mab-21 like 3", "type": "synonym", "evidence": [ { "id": "A0A8V1A7G6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7G6/entry#names_and_taxonomy" } ] }, { "name": "protein mab-21-like 3 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_024999341", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024999341" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_024999341", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024999341" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7G6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7G6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MAB21L3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7G6", "locus": { "chromosome": "1", "start_pos": 80369624, "end_pos": 80383881, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010025382", "url": "https://www.ensembl.org/id/ENSGALG00010025382" } ] } } ], "crossref": [ { "id": "A0A8V1A7G6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A7G6", "database": "AlphaFoldDB", "categories": [] }, { "id": "770247", "url": "https://www.ncbi.nlm.nih.gov/gene/770247", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR024810", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024810", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046903", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046903", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046906", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046906", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:770247", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:770247", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WSKKARW", "url": "https://omabrowser.org/oma/group/WSKKARW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A2Q3", "url": "https://www.orthodb.org/?gene=A0A8V1A2Q3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A510", "url": "https://www.orthodb.org/?gene=A0A8V1A510", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A7F6", "url": "https://www.orthodb.org/?gene=A0A8V1A7F6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A7G6", "url": "https://www.orthodb.org/?gene=A0A8V1A7G6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10656", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10656", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10656:SF30", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10656:SF30", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03281", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03281", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF20266", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20266", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_024999341", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024999341", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1A2Q3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2Q3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A2Q3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2Q3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A510", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A510", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A510-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A510-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A7F6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7F6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A7F6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7F6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A7G6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7G6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A7G6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7G6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKPFTDEDVEIYIQSKVEPRHYLVSKTVEEVQKIIQQLTTEISYKATRFQAISNSGIHNENIKVLAPSQFLITVPLRGLTGYRESQVRHWRYYTVHGAKLLSSVRDPEELHQWLEVEQFSKSLQQWHETDVNIEGDLVPAKVLVVFRELVEKSIASCNLSNKVTVLESFSSVVRVAVETSEFQVEVELAPTVEIPTCWPEKARWPRCLKRWPSQEKVQCIKSLGFDLLARSNYHWQLCFSRAEHMLMEGLDEDGGCRMKCFRVMRQMKEDVWCAGNKPVITAYHLQTVLFWTCEKYPRTKDWRCFHEAFLRLVQKLHKCVSQHFLKHYFVKNTNLLKYANTSDLDMVASKLAVFLENPVFCLD", "length": 363, "header": "tr|A0A8V1A7G6-1|A0A8V1A7G6_CHICK Isoform 1 of Mab-21 like 3 OS=Gallus gallus OX=9031 GN=MAB21L3 PE=3 SV=1 CANONICAL=A0A8V1A7G6-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A2Q3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7G6/entry#A0A8V1A2Q3-1", "sequence": { "sequence": "MKPFTDEDVEIYIQSKVEPRHYLVSKTVEEVQKIIQQLTTEISYKATRFQAISNSGIHNENIKDQPALLAKWSALLRGKRPFHPSIQVLAPSQFLITVPLRGLTGYRESQVRHWRYYTVHGAKLLSSVRDPEELHQWLEVEQFSKSLQQWHETDVNIEGDLVPAKVLVVFRELVEKSIASCNLSNKVTVLESFSSVVRVAVETSEFQVEVELAPTVEIPTCWPEKARWPRCLKRWPSQEKVQCIKSLGFDLLARSNYHWQLCFSRAEHMLMEGLDEDGGCRMKCFRVMRQMKEDVWCAGNKPVITAYHLQTVLFWTCEKYPRTKDWRCFHEAFLRLVQKLHKCVSQHFLKHYFVKNTNLLKYANTSDLDMVASKLAVFLENPVFCLD", "length": 387, "header": "tr|A0A8V1A2Q3-1|A0A8V1A7G6_CHICK Computationally mapped isoform of Mab-21 like 3 OS=Gallus gallus OX=9031 GN=MAB21L3 PE=3 SV=1 CANONICAL=A0A8V1A7G6-1" }, "locus": { "chromosome": "1", "start_pos": 80383851, "end_pos": 80370652, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010061987.1", "url": "https://www.ensembl.org/id/ENSGALT00010061987.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038281.1", "url": "https://www.ensembl.org/id/ENSGALP00010038281.1" } ] } }, { "isoform_ac": "A0A8V1A510-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7G6/entry#A0A8V1A510-1", "sequence": { "sequence": "MVEPRHYLVSKTVEEVQKIIQQLTTEISYKATRFQAISNSGIHNENIKVLAPSQFLITVPLRGLTGYRESQVRHWRYYTVHGAKLLSSVRDPEELHQWLEVEQFSKSLQQWHETDVNIEGDLVPAKVLVVFRELVEKSIASCNLSNKVTVLESFSSVVRVAVETSEFQVEVELAPTVEIPTCWPEKARWPRCLKRWPSQEKVQCIKSLGFDLLARSNYHWQLCFSRAEHMLMEGLDEDGGCRMKCFRVMRQMKEDVWCAGNKPVITAYHLQTVLFWTCEKYPRTKDWRCFHEAFLRLVQKLHKCVSQHFLKHYFVKNTNLLKYANTSDLDMVASKLAVFLENPVFCLD", "length": 348, "header": "tr|A0A8V1A510-1|A0A8V1A7G6_CHICK Computationally mapped isoform of Mab-21 like 3 OS=Gallus gallus OX=9031 GN=MAB21L3 PE=3 SV=1 CANONICAL=A0A8V1A7G6-1" }, "locus": { "chromosome": "1", "start_pos": 80380502, "end_pos": 80370652, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010061983.1", "url": "https://www.ensembl.org/id/ENSGALT00010061983.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038278.1", "url": "https://www.ensembl.org/id/ENSGALP00010038278.1" } ] } }, { "isoform_ac": "A0A8V1A7F6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7G6/entry#A0A8V1A7F6-1", "sequence": { "sequence": "STPSLVLWSATHLSFWNKPACLLRTDRTRAKDQPALLAKWSALLRGKRPFHPSIQVLAPSQFLITVPLRGLTGYRESQVRHWRYYTVHGAKLLSSVRDPEELHQWLEVEQFSKSLQQWHETDVNIEGDLVPAKVLVVFRELVEKSIASCNLSNKVTVLESFSSVVRVAVETSEFQVEVELAPTVEIPTCWPEKARWPRCLKRWPSQEKVQCIKSLGFDLLARSNYHWQLCFSRAEHMLMEGLDEDGGCRMKCFRVMRQMKEDVWCAGNKPVITAYHLQTVLFWTCEKYPRTKDWRCFHEAFLRLVQKLHKCVSQHFLKHYFVKNTNLLKYANTSDLDMVASKLAVFLENPVFCLD", "length": 355, "header": "tr|A0A8V1A7F6-1|A0A8V1A7F6_CHICK Computationally mapped isoform of Mab-21 like 3 OS=Gallus gallus OX=9031 GN=MAB21L3 PE=3 SV=1 CANONICAL=A0A8V1A7G6-1" }, "locus": { "chromosome": "1", "start_pos": 80379199, "end_pos": 80370652, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010061976.1", "url": "https://www.ensembl.org/id/ENSGALT00010061976.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038272.1", "url": "https://www.ensembl.org/id/ENSGALP00010038272.1" } ] } }, { "isoform_ac": "A0A8V1A7G6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7G6/entry#A0A8V1A7G6-1", "sequence": { "sequence": "MKPFTDEDVEIYIQSKVEPRHYLVSKTVEEVQKIIQQLTTEISYKATRFQAISNSGIHNENIKVLAPSQFLITVPLRGLTGYRESQVRHWRYYTVHGAKLLSSVRDPEELHQWLEVEQFSKSLQQWHETDVNIEGDLVPAKVLVVFRELVEKSIASCNLSNKVTVLESFSSVVRVAVETSEFQVEVELAPTVEIPTCWPEKARWPRCLKRWPSQEKVQCIKSLGFDLLARSNYHWQLCFSRAEHMLMEGLDEDGGCRMKCFRVMRQMKEDVWCAGNKPVITAYHLQTVLFWTCEKYPRTKDWRCFHEAFLRLVQKLHKCVSQHFLKHYFVKNTNLLKYANTSDLDMVASKLAVFLENPVFCLD", "length": 363, "header": "tr|A0A8V1A7G6-1|A0A8V1A7G6_CHICK Isoform 1 of Mab-21 like 3 OS=Gallus gallus OX=9031 GN=MAB21L3 PE=3 SV=1 CANONICAL=A0A8V1A7G6-1" }, "locus": { "chromosome": "1", "start_pos": 80383851, "end_pos": 80370652, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010061988.1", "url": "https://www.ensembl.org/id/ENSGALT00010061988.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038282.1", "url": "https://www.ensembl.org/id/ENSGALP00010038282.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:770247", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:770247", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8D0IHT2-1", "protein_name": "Mab-21 like 3", "gene_name": "MAB21L3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MYTFPEKFRPQRRTSLATLLTSAVCTERQAENIAVPLRIDQEAMKSPTEGNLDDCLLNKVDLRRQWISQMVEEVQKVVHHLTTEISHQDIRFQAIPCSDTYNENIKVLAPTHFLVTVPLRGLAGYREARQKRWRYYTLQGGRLPCPLRDPEALQQWLEVEQFLKNLWQWHEADVNIEGDIVPARVLQVFRKLVENAIETCHLPGNEVSMLMDRPGVWVAVETFAGPVELELIPSVEIPTSWSKKARWPPCLRRWPSAERVQCIKSFGFSLLACSNYHWQLSFLRAEQVLLEQLDEDGGCRRKCFQALRQMKEDVWCPGKRPVITSHHLQMVLFWTCEKYPHPKDWRIFSKAFLRLVRKLHKCVSQHFLKHYFVRKSNLLRYANSGELDAMAQKLAFFLKNPEITLS", "length": 406 }, "evidence": [ { "id": "A0A8V1A7G6", "url": "https://omabrowser.org/oma/group/A0A8V1A7G6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A8E4S7-1", "protein_name": "Protein mab-21-like 3", "gene_name": "mab21L3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTNCTDEDLDNYLLNQVDLRHRQVSKCVEDVQKIIKDLTTEVSSKDARFQSIANAGVHNASLKDQPALMSKWSALLRGRCAYNPAIQVLSPTLYLISVPLQGLMGYKERRTRQWRYYTLTGSRLLSPVREPEKLHQWLELESFVNPSQEWHDARMTIEGDIVPAKVVNVFKDLLETSIKTRGLTNKVSVLESVGTAVRVAVETSEAQIEVKLVPTVELMNYWPKRARWPRLFRRWPSTERARCIKSFGFNLMASSNYHWLLSFSRAEQVLLSNIDEDGGCRRKCYRVVRQLKEDGWCPGSKPVITAFHLQTLLFWTCEKYPCTRDWKDFRGCVLRLVQKLHKCVSQHYLRHYFIRSHNLLKYSNTNELDEVAKKINHFLENPGTYIH", "length": 387 }, "evidence": [ { "id": "A0A8V1A7G6", "url": "https://omabrowser.org/oma/group/A0A8V1A7G6/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "D4AE70-1", "protein_name": "Mab-21 like 3", "gene_name": "Mab21l3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": 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"MADEFFHAGKENCSEQARRSQVSGPRSQFQRSFIQRVTLLGKLPTRFVLHRERKQKVAAILGVDQEAMKSLPEGDLDHCLLSKVDLRRQQISQTMEEVQKIIHLLTTEISRQDSRFEAVPVSDTHNESIKVLAPSLFHVTVPLKGLAGYKGVQRQRWRYYNVQGAKLTCPLRDPEGLQQWLETEMFMKTLWQWHKADVNIEGDIVPAKVLQVFRTLVENAVRTCHLSGKVTVLEKRTTVWVAMETSTGQVELELAPTVEIPTTWPEKAQWPRCLKRWPSPERVECIKSFGFNLVAQSAYHWQLSFSQAEQVLFEQLDEDGGCRRQCFQVLRQLKEDVWCPGRRPVITTHHLQTVLFWTCEKYPHLKDWQVFHQALLRLVRKLHRCVSQHFLKHYFVPKSNLLQSANPSELDAVAQKVAFFLKNPQVELP", "length": 429 }, "evidence": [ { "id": "A0A8V1A7G6", "url": "https://omabrowser.org/oma/group/A0A8V1A7G6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8N8X9-1", "protein_name": "Protein mab-21-like 3", "gene_name": "MAB21L3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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"glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AAH8-1", "uniprot_ac": "A0A8V1AAH8", "uniprot_id": "A0A8V1AAH8_CHICK", "mass": { "chemical_mass": 50698.0, "monoisotopic_mass": 50698.0 }, "refseq": { "ac": "XP_004948845", "name": "UBX domain-containing protein 6 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004948845" }, "gene_names": [ { "name": "UBXN6", "type": "recommended", "evidence": [ { "id": "A0A8V1AAH8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAH8" } ] }, { "name": "UBXN6", "type": "synonym", "evidence": [ { "id": "XP_004948845", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004948845" } ] } ], "protein_names": [ { "name": "UBX domain-containing protein 6", "type": "recommended", "evidence": [ { "id": "A0A8V1AAH8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAH8/entry#names_and_taxonomy" } ] }, { "name": "UBX domain-containing protein 1", "type": "synonym", "evidence": [ { "id": "A0A8V1AAH8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAH8/entry#names_and_taxonomy" } ] }, { "name": "UBX domain-containing protein 6 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_004948845", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004948845" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052559.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004948845.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004948845", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004948845" } ] }, { "annotation": "May negatively regulate the ATPase activity of VCP, an ATP-driven segregase that associates with different cofactors to control a wide variety of cellular processes. As a cofactor of VCP, it may play a role in the transport of CAV1 to lysosomes for degradation. It may also play a role in endoplasmic reticulum-associated degradation (ERAD) of misfolded proteins. Together with VCP and other cofactors, it may play a role in macroautophagy, regulating for instance the clearance of damaged lysosomes.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAH8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAH8#function" }, { "database": "UniProtKB", "id": "ARBA00059509", "url": "https://www.uniprot.org/uniprotkb/ARBA00059509#function" }, { "database": "UniProtKB", "id": "A0A8V1A2X4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2X4#function" }, { "database": "UniProtKB", "id": "A0A8V1ADA5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADA5#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAH8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAH8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "UBXN6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAH8", "locus": { "chromosome": "28", "start_pos": 2957003, "end_pos": 2961790, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027208", "url": "https://www.ensembl.org/id/ENSGALG00010027208" } ] } } ], "crossref": [ { "id": "A0A8V1AAH8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AAH8", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd10460", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd10460", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd16119", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16119", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "428329", "url": "https://www.ncbi.nlm.nih.gov/gene/428329", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001012", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001012", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018997", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018997", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029071", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029071", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036339", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036339", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042774", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042774", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "VFFRCPM", "url": "https://omabrowser.org/oma/group/VFFRCPM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A2X4", "url": "https://www.orthodb.org/?gene=A0A8V1A2X4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AAH8", "url": "https://www.orthodb.org/?gene=A0A8V1AAH8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ADA5", "url": "https://www.orthodb.org/?gene=A0A8V1ADA5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23153", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23153", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23153:SF38", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23153:SF38", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00789", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00789", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF09409", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09409", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004948845", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004948845", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1A2X4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2X4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A2X4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2X4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AAH8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAH8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AAH8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAH8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ADA5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADA5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ADA5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADA5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRKFFQEIKADLKFRSAGPGQKLSEPARYGALRRRVPKEKPKAEAAPKPRHGPTDEAQMAAAAALARMELKPKAKPPSSQGAIKNQVRKELMAEAAASVKGVSADQEDPAFSDKETAAEPSVSGVYFICPLTSTVVRKDEKEKHIREAIKSYFSVDPVAASIMEIHTLNKDREKVRVGVETMAKYLDNIYLHPEEEKYQKIKLQNKVFQERINCLEGIHRFFQSVGFETRTLPVPGQDTTEEYYVLKEEMLTKLEDLKDYKEQLLSCEPLRLQLDRQLCVFKPSPEAARFELPNDFYNLTAEEIKREQRLRTEAVEKASMLRTRAMREKEEQREMRKYNYTLLRVRLPDGYLLQGTFYAREPVSVLYNFVREALRDNWLPFELLGPGGLKLTDENLAFNECGLVPSALLTLAWDAAVMSDIEASGQEQPASPLKPELLSHVQTLS", "length": 445, "header": "tr|A0A8V1AAH8-1|A0A8V1AAH8_CHICK Isoform 1 of UBX domain-containing protein 6 OS=Gallus gallus OX=9031 GN=UBXN6 PE=1 SV=1 CANONICAL=A0A8V1AAH8-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A2X4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAH8/entry#A0A8V1A2X4-1", "sequence": { "sequence": "MRKFFQEIKADLKFRSAGPGQKLSEPARVPKEKPKAEAAPKPRHGPTDEAQMAAAAALARMELKPKAKPPSSQGAIKNQVRKELMAEAAASVKGVSADQEDPAFSDKETAAEPSVSGVYFICPLTSTVVRKDEKEKHIREAIKSYFSVDPVAASIMEIHTLNKDREKVRVGVETMAKYLDNIYLHPEEEKYQKIKLQNKVFQERINCLEGIHRFFQSVGFETRTLPVPGQDTTEEYYVLKEEMLTKLEDLKDYKEQLLSCEPLRLQLDRQLCVFKPSPEAARFELPNDFYNLTAEEIKREQRLRTEAVEKASMLRTRAMREKEEQREMRKYNYTLLRVRLPDGYLLQGTFYAREPVSVLYNFVREALRDNWLPFELLGPGGLKLTDENLAFNECGLVSKRWHLAQESPGGNGALLVRVSCCS", "length": 422, "header": "tr|A0A8V1A2X4-1|A0A8V1AAH8_CHICK Computationally mapped isoform of UBX domain-containing protein 6 OS=Gallus gallus OX=9031 GN=UBXN6 PE=1 SV=1 CANONICAL=A0A8V1AAH8-1" }, "locus": { "chromosome": "28", "start_pos": 2961721, "end_pos": 2958007, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065960.1", "url": "https://www.ensembl.org/id/ENSGALT00010065960.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040226.1", "url": "https://www.ensembl.org/id/ENSGALP00010040226.1" } ] } }, { "isoform_ac": "A0A8V1AAH8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAH8/entry#A0A8V1AAH8-1", "sequence": { "sequence": "MRKFFQEIKADLKFRSAGPGQKLSEPARYGALRRRVPKEKPKAEAAPKPRHGPTDEAQMAAAAALARMELKPKAKPPSSQGAIKNQVRKELMAEAAASVKGVSADQEDPAFSDKETAAEPSVSGVYFICPLTSTVVRKDEKEKHIREAIKSYFSVDPVAASIMEIHTLNKDREKVRVGVETMAKYLDNIYLHPEEEKYQKIKLQNKVFQERINCLEGIHRFFQSVGFETRTLPVPGQDTTEEYYVLKEEMLTKLEDLKDYKEQLLSCEPLRLQLDRQLCVFKPSPEAARFELPNDFYNLTAEEIKREQRLRTEAVEKASMLRTRAMREKEEQREMRKYNYTLLRVRLPDGYLLQGTFYAREPVSVLYNFVREALRDNWLPFELLGPGGLKLTDENLAFNECGLVPSALLTLAWDAAVMSDIEASGQEQPASPLKPELLSHVQTLS", "length": 445, "header": "tr|A0A8V1AAH8-1|A0A8V1AAH8_CHICK Isoform 1 of UBX domain-containing protein 6 OS=Gallus gallus OX=9031 GN=UBXN6 PE=1 SV=1 CANONICAL=A0A8V1AAH8-1" }, "locus": { "chromosome": "28", "start_pos": 2961721, "end_pos": 2957480, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065959.1", "url": "https://www.ensembl.org/id/ENSGALT00010065959.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040225.1", "url": "https://www.ensembl.org/id/ENSGALP00010040225.1" } ] } }, { "isoform_ac": "A0A8V1ADA5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAH8/entry#A0A8V1ADA5-1", "sequence": { "sequence": "MRKFFQEIKADLKFRSAGPGQKLSEPARVPKEKPKAEAAPKPRHGPTDEAQMAAAAALARMELKPKAKPPSSQGAIKNQGVYFICPLTSTVVRKDEKEKHIREAIKSYFSVDPVAASIMEIHTLNKDREKVRVGVETMAKYLDNIYLHPEEEKYQKIKLQNKVFQERINCLEGIHRFFQSVGFETRTLPVPGQDTTEEYYVLKEEMLTKLEDLKDYKEQLLSCEPLRLQLDRQLCVFKPSPEAARFELPNDFYNLTAEEIKREQRLRTEAVEKASMLRTRAMREKEEQREMRKYNYTLLRVRLPDGYLLQGTFYAREPVSVLYNFVREALRDNWLPFELLGPGGLKLTDENLAFNECGLVPSALLTLAWDAAVMSDIEASGQEQPASPLKPELLSHVQTLS", "length": 401, "header": "tr|A0A8V1ADA5-1|A0A8V1ADA5_CHICK Computationally mapped isoform of UBX domain-containing protein 6 OS=Gallus gallus OX=9031 GN=UBXN6 PE=1 SV=1 CANONICAL=A0A8V1AAH8-1" }, "locus": { "chromosome": "28", "start_pos": 2961721, "end_pos": 2957480, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065958.1", "url": "https://www.ensembl.org/id/ENSGALT00010065958.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040224.1", "url": "https://www.ensembl.org/id/ENSGALP00010040224.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2K012-1", "protein_name": "UBX domain-containing protein 6", "gene_name": "Ubxn6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLSCPPPPPGGCRGPEGEPVVLATASADRKMAPRPRGAARRLSRVPGGTSVAEIFSFRWLAACSSPTRALRPPPRGPRRRAAAMKKFFQEIKADIKFKSAGPGQKLTDSAGEKTSKGKSPQLALRQPRQGPTDEAQMAAAAALARLEQKQPRARGPTSQDSIRNQVRKELQAEATSSNNPGAPGTNSVPETKDEISPHLAVPGVFFICPLTGVTLRRDQRDAHIKQAILSHFSTDPVAASIMKIHTFNRDRDRVKLGVDTIAKYLDNIHLHPEEEKYQKIKLQNKVFQERINCLEGSHEFFEAIGFKKVTLPVPDQEGQEFYVLGEDARAQPQNLERHKQQLLGAEPVRATLDRQLRVFRPSALASHFELPSDFFSLTAEEVKREQRLRTEAVERLSSLRTKAMREKEEQRELRKYTYALLRVRLPDGCLLQGTFYAREKLSVLFQFVREALQNDWLPFELRASGGQKLEENEALALNECGLVPSALLTFSWDASVLEDIRAAGAEPAKSVLRPELLAAIEQLS", "length": 524 }, "evidence": [ { "id": "A0A8V1AAH8", "url": "https://omabrowser.org/oma/group/A0A8V1AAH8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0ABI0NJJ8-1", "protein_name": "UBX domain-containing protein 6", "gene_name": "UBXN6", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MKKFFQEIKADIKFKSAGPGQKLTESVGEKAPKEKPSQPPVRQPRQGPTNEAQMAAAAALARLEQKQPRARGPTSQDSIRNQVRKELRAEAAVSGDPEAPGSNTAPEPKEEGSAHLAVPGVYFTCPLTGAILRKDQRDARIREAILMHFSTDPVAASIMKIHTFNKDRDRVKLGVDTIAKYLDNIHLHPEEEKYRKIKVQNKVFQERIHCLEGTHEFFEAIGFQKVLLPIPDQEGPEEFYVLSEAALAQPQSLEWHKEQLLSAEPVRATLARQRRVFRPSTLASQFDLPADFFNLTAEEIKREQRLRSEAVERLSVLRTKAMREREEQREMRKYTYTLLRVRLPDGCLLQGTFYARERVAALYGFVREALQNDWLPFELLASGGQKLSEDENLAFNECGLVPSALLTFSWDAAVLEDIRAAGTQPDTSILKPELLSAIEKL", "length": 441 }, "evidence": [ { "id": "A0A8V1AAH8", "url": "https://omabrowser.org/oma/group/A0A8V1AAH8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3HCG0-1", "protein_name": "UBX domain-containing protein 6", "gene_name": "Ubxn6", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MKKFFQEIKADIKFKSAGPGQKLTDSAGQKTPKEKSPQQALQQPRQGPTDEAQMAAAAALARLEQKQPRARGPTSQDSIRNQVRKELQAEATSSNSPGAPGTNLAPEPKEEISPHLAVPGVYFICPLTGVTLRRDQRDAHIKEAILSHFSTDPVAASIMKIHTFNRDRDRVKLGVDTIAKYLDNIHLHPEEEKYQKIKLQNKVFQERINCLEGTHEFFEAIGFKKMTLPVPDQEGSEEFYVLGEATRAQPQSLEQHKQQLLSAEPVRAMLDRQRRVFRPSALASHFELPADFFSLTAEEVKREQRLRTEAVERLSSLRTKAMREKEEQRELRKYTYALLRVRLPDGCLLQGTFYARERLPVLFQFVREALQNDWLPFELRASGGQRLVEDEALALNECGLVPSALLTFSWDASVLEDMRAAGAEPATCVLRPELLAAIEQLS", "length": 442 }, "evidence": [ { "id": "A0A8V1AAH8", "url": "https://omabrowser.org/oma/group/A0A8V1AAH8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q1LYI0-1", "protein_name": "UBX domain-containing protein 6", "gene_name": "ubxn6", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MKKFFDDIKKDIKFKSAGPGKKLTDESSSKPQASQASHAASRKAPTAGAQMAGAAALARIEQQHRPKVHTSQDAIRNQVKRELEAEAAAVVASLKNTEIEGSAVPQRDSSSFSVSGVFFTCPLTGKTVTKAERELHIKEAILMRFSEDAIEASIMMIHTFNKDKEKVKAAIDIISKYIENICKNPTEEKYRKIKVGNKVFQEKVSGIEGAREYLQALGFESSTLPIDGEEKTEDFLVLPEQDSDALEQMKIHLERLQKGEAVRAKLDRQLQVFRPSQNATHFELPPDFYNLSAEELKKEQQLKSEMVERNAMLRTKAMREKDEQRERRKYNYALLRVRLPDGNILQGTFLAWERLSALYQFVRDSLENDWQPFELMAPGGQKLKDDEETPINECNLAPAALLTFSWDAAVQADIAAAGGKTAVLLKQALLENIKSLS", "length": 437 }, "evidence": [ { "id": "A0A8V1AAH8", "url": "https://omabrowser.org/oma/group/A0A8V1AAH8/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q99PL6-1", "protein_name": "UBX domain-containing protein 6", "gene_name": "Ubxn6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKKFFQEIKADIKFKSAGPGQKLTDSAGEKTTKGKSPQLALRQPRQGPTDEAQMAAAAALARLEQKQPRARGPTSQDSIRNQVRKELQAEATSSNNPGAPGTNSVPEPKEEISPHLAVPGVFFICPLTGVTLRRDQRDAHIKQAILSHFSTDPVAASIMKIHTFNRDRDRVKLGVDTIAKYLDNIHLHPEEEKYQKIKLQNKVFQERINCLEGSHEFFEAIGFKKVTLPVPDQEGQEEFYVLGEDARAQPQNLARHKQQLLDAEPVRATLDRQLRVFRPSALASHFELPSDFFSLTAEEVKREQRLRTEAVERLSSLRTKAMREKEEQRELRKYTYALVRVRLPDGCLLQGTFYAREKLSALFRFVREALQNDWLPFELRASGGQKLEENEALALNECGLVPSALLTFSWDASVLEDIRAAGAEPAKSVLRPELLAAIEQLS", "length": 442 }, "evidence": [ { "id": "A0A8V1AAH8", "url": "https://omabrowser.org/oma/group/A0A8V1AAH8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9BZV1-1", "protein_name": "UBX domain-containing protein 6", "gene_name": "UBXN6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKKFFQEFKADIKFKSAGPGQKLKESVGEKAHKEKPNQPAPRPPRQGPTNEAQMAAAAALARLEQKQSRAWGPTSQDTIRNQVRKELQAEATVSGSPEAPGTNVVSEPREEGSAHLAVPGVYFTCPLTGATLRKDQRDACIKEAILLHFSTDPVAASIMKIYTFNKDQDRVKLGVDTIAKYLDNIHLHPEEEKYRKIKLQNKVFQERINCLEGTHEFFEAIGFQKVLLPAQDQEDPEEFYVLSETTLAQPQSLERHKEQLLAAEPVRAKLDRQRRVFQPSPLASQFELPGDFFNLTAEEIKREQRLRSEAVERLSVLRTKAMREKEEQRGLRKYNYTLLRVRLPDGCLLQGTFYARERLGAVYGFVREALQSDWLPFELLASGGQKLSEDENLALNECGLVPSALLTFSWDMAVLEDIKAAGAEPDSILKPELLSAIEKLL", "length": 441 }, "evidence": [ { "id": "A0A8V1AAH8", "url": "https://omabrowser.org/oma/group/A0A8V1AAH8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAH8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAH8" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAH8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAH8" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAH8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAH8" } ], "pmid": "" }, { "name": "lysosomal membrane", "id": "GO:0005765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005765", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAH8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAH8" } ], "pmid": "" }, { "name": "late endosome membrane", "id": "GO:0031902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031902", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAH8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAH8" } ], "pmid": "" }, { "name": "early endosome membrane", "id": "GO:0031901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031901", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAH8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAH8" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAH8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAH8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "response to stress", "id": "GO:0006950", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006950", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAH8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAH8" } ], "pmid": "" }, { "name": "protein unfolding", "id": "GO:0043335", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043335", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAH8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAH8" } ], "pmid": "" }, { "name": "ERAD pathway", "id": "GO:0036503", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036503", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAH8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAH8" } ], "pmid": "" }, { "name": "mitophagy", "id": "GO:0000423", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000423", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAH8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAH8" } ], "pmid": "" }, { "name": "endosome to lysosome transport via multivesicular body sorting pathway", "id": "GO:0032510", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032510", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAH8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAH8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "ATPase binding", "id": "GO:0051117", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051117", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAH8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAH8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 298, "end_pos": 300, "annotation": "n_glycosylation_sequon" }, { "start_pos": 339, "end_pos": 341, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AAH8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAH8" }, { "id": "PS50033", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50033" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "UBX", "eco_id": "ECO_0000259", "start_pos": 336, "end_pos": 411, "start_aa": "Arg", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 298, "end_pos": 300 }, { "start_pos": 339, "end_pos": 341 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AAG0-1", "uniprot_ac": "A0A8V1AAG0", "uniprot_id": "A0A8V1AAG0_CHICK", "mass": { "chemical_mass": 29408.0, "monoisotopic_mass": 29408.0 }, "refseq": { "ac": "XP_004945627", "name": "diablo homolog, mitochondrial isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004945627" }, "gene_names": [ { "name": "DIABLO", "type": "recommended", "evidence": [ { "id": "A0A8V1AAG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAG0" } ] }, { "name": "DIABLO", "type": "synonym", "evidence": [ { "id": "XP_004945627", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004945627" } ] } ], "protein_names": [ { "name": "Direct IAP-binding protein with low pI", "type": "recommended", "evidence": [ { "id": "A0A8V1AAG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAG0/entry#names_and_taxonomy" } ] }, { "name": "diablo homolog, mitochondrial isoform X2", "type": "synonym", "evidence": [ { "id": "XP_004945627", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004945627" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052546.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004945627.3. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004945627", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004945627" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAG0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAG0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "DIABLO", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAG0", "locus": { "chromosome": "15", "start_pos": 5813751, "end_pos": 5818864, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010025459", "url": "https://www.ensembl.org/id/ENSGALG00010025459" } ] } } ], "crossref": [ { "id": "A0A8V1AAG0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AAG0", "database": "AlphaFoldDB", "categories": [] }, { "id": "416860", "url": "https://www.ncbi.nlm.nih.gov/gene/416860", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR009062", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009062", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015142", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015142", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416860", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416860", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1A310", "url": "https://www.orthodb.org/?gene=A0A8V1A310", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AAG0", "url": "https://www.orthodb.org/?gene=A0A8V1AAG0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR32247", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR32247", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR32247:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR32247:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF09057", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09057", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-111457", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-111457", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-111463", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-111463", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-111464", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-111464", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-111469", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-111469", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9627069", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9627069", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_004945627", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004945627", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1A310", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A310", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A310-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A310-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AAG0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAG0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AAG0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAG0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASLPAYRPLPRWRRGPSGCGNIAGSRSPPPAAADDPCSGVSVLTVSRMPRHGLPALAGTGRRGLPGGSGRWRRAVGAGLGAALCAVPVAEKQNSASLSNDALIKRAVTLVTDSTSTLLSQTTYALIEALTEYTKAVYTLVSLYKQYTNLLGKMNSDEVDAVWQVVIGARVDMTTKQQEYLKLESSWMTALRLSEMAAEAAYQSGADQASVTARSHIQLIKSQVQEVRQLSQKAETKLAEAQTEELLKTQGEESTLPQGILGSTDAGEDPYLRED", "length": 275, "header": "tr|A0A8V1AAG0-1|A0A8V1AAG0_CHICK Isoform 1 of Direct IAP-binding protein with low pI OS=Gallus gallus OX=9031 GN=DIABLO PE=1 SV=1 CANONICAL=A0A8V1AAG0-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A310-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAG0/entry#A0A8V1A310-1", "sequence": { "sequence": "ARQQRSRAAPTTVGRLTAPPPLTATVNTTAAPRALPTCPPSAHAPIRTTLPAWRHFRRTAHSQDGGAVLLAAGLVLSPEKQNSASLSNDALIKRAVTLVTDSTSTLLSQTTYALIEALTEYTKAVYTLVSLYKQYTNLLGKMNSDEVDAVWQVVIGARVDMTTKQQEYLKLESSWMTALRLSEMAAEAAYQSGADQASVTARSHIQLIKSQVQEVRQLSQKAETKLAEAQTEELLKTQGEESTLPQGILGSTDAGEDPYLRED", "length": 263, "header": "tr|A0A8V1A310-1|A0A8V1AAG0_CHICK Computationally mapped isoform of Direct IAP-binding protein with low pI OS=Gallus gallus OX=9031 GN=DIABLO PE=1 SV=1 CANONICAL=A0A8V1AAG0-1" }, "locus": { "chromosome": "15", "start_pos": 5818665, "end_pos": 5815007, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010062143.1", "url": "https://www.ensembl.org/id/ENSGALT00010062143.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038407.1", "url": "https://www.ensembl.org/id/ENSGALP00010038407.1" } ] } }, { "isoform_ac": "A0A8V1AAG0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAG0/entry#A0A8V1AAG0-1", "sequence": { "sequence": "MASLPAYRPLPRWRRGPSGCGNIAGSRSPPPAAADDPCSGVSVLTVSRMPRHGLPALAGTGRRGLPGGSGRWRRAVGAGLGAALCAVPVAEKQNSASLSNDALIKRAVTLVTDSTSTLLSQTTYALIEALTEYTKAVYTLVSLYKQYTNLLGKMNSDEVDAVWQVVIGARVDMTTKQQEYLKLESSWMTALRLSEMAAEAAYQSGADQASVTARSHIQLIKSQVQEVRQLSQKAETKLAEAQTEELLKTQGEESTLPQGILGSTDAGEDPYLRED", "length": 275, "header": "tr|A0A8V1AAG0-1|A0A8V1AAG0_CHICK Isoform 1 of Direct IAP-binding protein with low pI OS=Gallus gallus OX=9031 GN=DIABLO PE=1 SV=1 CANONICAL=A0A8V1AAG0-1" }, "locus": { "chromosome": "15", "start_pos": 5818510, "end_pos": 5815007, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010062141.1", "url": "https://www.ensembl.org/id/ENSGALT00010062141.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038406.1", "url": "https://www.ensembl.org/id/ENSGALP00010038406.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:416860", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416860", "resource": "KEGG Pathway" }, { "id": "R-GGA-111457", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-111457", "resource": "Reactome", "description": "Release of apoptotic factors from the mitochondria" }, { "id": "R-GGA-111463", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-111463", "resource": "Reactome", "description": "SMAC (DIABLO) binds to IAPs" }, { "id": "R-GGA-111464", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-111464", "resource": "Reactome", "description": "SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes" }, { "id": "R-GGA-111469", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-111469", "resource": "Reactome", "description": "SMAC, XIAP-regulated apoptotic response" }, { "id": "R-GGA-9627069", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9627069", "resource": "Reactome", "description": "Regulation of the apoptosome activity" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAG0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAG0" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": 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record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052546.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_415157.4. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_415157", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_415157" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A857", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A857" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "KNTC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A857", "locus": { "chromosome": "15", "start_pos": 5956659, "end_pos": 5924031, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010025527", "url": "https://www.ensembl.org/id/ENSGALG00010025527" } ] } } ], "crossref": [ { "id": "416865", "url": "https://www.ncbi.nlm.nih.gov/gene/416865", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019527", 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"MLVTMWNDIEILVNDDTRREQLSVCLGQECGSALYQVDSLLQITSSEKISVNPQLYACSSRDGSIIVVDRSVVLLDSTGQALQLHIQFDTNVDVVGMCQEKQFLVVGERSGNIHLVHIPSKKTLLTKILVETSSSEKTYLNLFIEKDTAVAGVYHMFILTDKGFFCIMCLPLAKTQEAINKMDMAAAMKLQGQIKTAFIATEEYHSLGCQNFVISNLANKIHMIIGGKGDYVLSKWEVDATNNLVSVRSFADSSLIKDAVKLQVLDNLLFVLDTENILSIWDVFSLTLIWDWPLIHVEEFLLTTESDSSSVMQQGLAGVKLIVMTTSTNKQMRSLMVFALPTMQQLYSLEVSIVSSLVLSGIGTDTIYFLEGIHENHQMPPEGPVSAVVMRSLTEALPENRLSRLLHKHKFTEAESFAIQFGLDVELVYKVKANTILEKLASASIGSYGQEVLLDYVNEAKENLHKIQDSQFVVDYCINAPWPLYETAQEMLNYAKVRILKKDDRTIVSPSDGTLVSLTEQVLRAQARLTTFYGAFGLEKFSGIAWTEFLNNEDVLKNILFQLEEGNLSCAQYLWLRHQADFEDTFDEKMLESLLNAIHVTVPLKELCLWLKNVVIPFLRRVVPKGQKVLAKWLEQGARNLELTDKANWPENGLQMAEIFFTSKNQDEMHLTSFGQWTPLKCSDCEEVHRLKKLVNDLQELTDLYRKYNCRLALCDFEKENTTTIVFRMFDKILAPELVPSILDKFIKPYLCEHNLQKDELLLQYIKDLLERCRTRSASVFETAWEAKAIAVTGCISDTDLKFDAVLQIMHGAVVPWSGAVEQLVKQHLEMNHVKVKLLQESYRLMEMKKLLRAYGIRDTNLLKDKEMIMRLVKYILKQDTPTSLEDALKMVEAYMLPTTEVYILRMIDLIDKERGEESLTLLKSLTTAEAEKVAERLTVWGRLVLQRKADNSEEQKTQMFMTKTLVEILKFLYKIQKDNPLKKDECEANLKTFNTLATLQEDFNIFLSVEDFGNPTLMSTLLEKHISAYETDKYPSKSRQEQTMNCKTKDGKLKNCSTESRLYRMALLLQRSEQELGTTLALRALGAGRVEDAVKICRNFYKNHCNKETGKLLFSTCQRLCHMLGGDVPMNTPEDMNLPAVIYEMACQAATICSPDLLLDSLELCKYTLAAKEIYRQCQIENYGFTAKTTCFGGDKDPYEEWTYNDFFNEDGIVLDSQIVLPVIYETISSLLPISENKLYPLDSTSLANCTFIRGQNLLLPARTPICAVLQNLMECSQCELALRLMVSSFGSCLQHGISNNMDLSLSEKLHDGNIQAETKSFLIAMKQTTASIITTSIMTLLHKVFNCRLIDQNLALGYCAILPREDMFNKLWGVINNTWQNYRKVLSVALVGAQLATQYGEAAEEKKFRELITDAEWGIQLGKFGISFETVFRQPPVRKKELIRTLVQNPEVGTDLILNYCRTFMLDSDAALQLCIETLLLKNANRNHAEDDSAEYSEKQSHYTLLARALEIIPLLKSTNDLVTSLSGILYKLDPYDYETIEIVLKVIQNADERNTSIHLNQALSLLKHLESYKRISPPVDLEHQYVSEHTIPLSPASETRLPFHLIFFRTAQCFWNIISAELSEESFPTLLLISKLMKVSLDTLHMSAAQHVFQKKLKPKIFEMRNTGYTSVVNKETTKTVQTIQSYLLSIINPEWAVAMAHKIAQEFPTGPDQIQALKFCLRLAEKWLKNTTAKDESHEKAEVLQKKLYMQYKRSATENVLITYKLNTAEYLKSIAKPANLIVLLYEHHSIDQRIQNPTGRDYPDIHMAAKEIAEINNLDMNKILNQLLNKWLCPNTLPSEKTQEIFADAQEDEELRRVIYLLQSHPMDYSSRMLFAITTSATSPIGINQLTFAHRSRALKCLLYLADTNTVESLFKKPIQKVKYFLKCFIYLAEFEVLNIPYTYESFHKSPKEGMIKGLWKNHSHEPTAVRLVTELSLEYKVYDFQLWNGLLQKLLGFNMIHYLRKVLIAITGIHSLWQIPSFSRAWRSVVLSPFLTASCPPSPKQIEECCECFVILLKCPVLADLDVIGIAKQYAQLDLPAFALGCLMLIPQSEKREQQIQAFLSTCNTETVLQQIDEHMNTGEVVAFASQIRSLILDSIINEKLYEKISKTKYFPLVKQQLMSTHRMKELVDYFANKNCIEDAAALIREYQEKYGNPTLLDKSSSDILKMYLNGPQETCVLELSSMKS", "length": 2235, "header": "tr|A0A8V1A857-1|A0A8V1A857_CHICK Isoform 1 of Kinetochore associated 1 OS=Gallus gallus OX=9031 GN=KNTC1 PE=4 SV=1 CANONICAL=A0A8V1A857-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A3A1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A857/entry#A0A8V1A3A1-1", "sequence": { "sequence": "MLVTMWNDIEILVNDDTRREQLSVCLGQECGSALYQVDSLLQITSSEKISVNPQLYACSSRDGSIIVVDRSVVLLDSTGQALQLHIQFDTNVDVVGMCQEKQFLVVGERSGNIHLVHIPSKKTLLTKILVETSSSEKTYLNLFIEKDTAVAGVYHMFILTDKGFFCIMCLPLAKTQEAINKMDMAAAMKLQGQIKTAFIATEEYHSLGCQNFVISNLANKIHMIIGGKGDYVLSKWEVDATNNLVSVRSFADSSLIKDAVKLQVLDNLLFVLDTENILSIWDVFSLTLIWDWPLIHVEEFLLTTESDSSSVMQQGLAGVKLIVMTTSTNKQMRSLMVFALPTMQQLYSLEVSIVSSLVLSGIGTDTIYFLEGIHENHQMPPEGPVSAVVMRSLTEALPENRLSRLLHKHKFTEAESFAIQFGLDVELVYKVKANTILEKLASASIGSYGQEVLLDYVNEAKENLHKIQDSQFVVDYCINAPWPLYETAQEMLNYAKVRILKKDDRTIVSPSDGTLVSLTEQVLRAQARLTTFYGAFGLEKFSGIAWTEFLNNEDVLKNILFQLEEGNLSCAQYLWLRHQADFEDTFDEKMLESLLNAIHVTVPLKELCLWLKNVVIPFLRRVVPKGQKVLAKWLEQGARNLELTDKANWPENGLQMAEIFFTSKNQDEMHLTSFGQWTPLKCSDCEEVHRLKKLVNDLQELTDLYRKYNCRLALCDFEKENTTTIVFRMFDKILAPELVPSILDKFIKPYLCEHNLQKDELLLQYIKDLLERCRTRSASVFETAWEAKAIAVTGCISDTDLKFDAVLQIMHGAVVPWSGAVEQLVKQHLEMNHVKVKLLQESYRLMEMKKLLRAYGIRDTNLLKDKEMIMRLVKYILKQDTPTSLEDALKMVEAYMLPTTEVYILRMIDLIDKERGEESLTLLKSLTTAEAEKVAERLTVWGRLVLQRKADNSEEQKTQMFMTKTLVEILKFLYKIQKDNPLKKDECEANLKTFNTLATLQEDFNIFLSVEDFGNPTLMSTLLEKHISAYETDKYPSKSRQEQTMNCKTKDGKLKNCSTESRLYRMALLLQRSEQELGTTLALRALGAGRVEDAVKICRNFYKNHCNKETGKLLFSTCQRLCHMLGGDVPMNTPEDMNLPAVIYEMACQAATICSPDLLLDSLELCKYTLAAKEIYRQCQIENYGFTAKTTCFGGDKDPYEEWTYNDFFNEDGIVLDSQIVLPVIYETISSLLPISENKLYPLDSTSLANCTFIRGQNLLLPARTPICAVLQNLMECSQCELALRLMVSSFGSCLQHGISNNMDLSLSEKLHDGNIQAETKSFLIAMKQTTASIITTSIMTLLHKVFNCRLIDQNLALGYCAILPREDMFNKLWGVINNTWQNYRKVLSVALVGAQLATQYGEAAEEKKFRELITDAEWGIQLGKFGISFETVFRQPPVRKKELIRTLVQNPEVGTDLILNYCRTFMLDSDAALQLCIETLLLKNANRNHAEDDSAEYSEKQSHYTLLARALEIIPLLKSTNDLVTSLSGILYKLDPYDYETIEIVLKVIQNADERNTSIHLNQALSLLKHLESYKRISPPVDLEHQYVSEHTIPLSPASETRLPFHLIFFRTAQCFWNIISAELSEESFPTLLLISKLMKVSLDTLHMSAAQHVFQKKLKPKIFEMRNTGYTSVVNKETTKTVQTIQSYLLSIINPEWAVAMAHKIAQEFPTGPDQIQALKFCLRLAEKWLKNTTAKDESHEKAEVLQKKLYMQYKRSATENVLITYKLNTAEYLKSIAKPANLIVLLYEHHSIDQRIQNPTGRDYPDIHMAAKEIAEINNLDMNKILNQLLNKWLCPNTLPSEKTQEIFADAQEDEELRRVIYLLQSHPMDYSSRMLFAITTSATSPIGINQLTFAHRSRALKCLLYLADTNTVESLFKKPIQKVKYFLKCFIYLAEFEVLNIPYTYESFHKSPKEGMIKGLWKNHSHEPTAVRLVTELSLEYKVYDFQLWNGLLQKLLGFNMIHYLRKVLIAITGIHSLWQIPSFSRAWRSVVLSPFLTASCPPSPKQIEECCECFVILLKCPVLADLDVIGIAKQYAQLDLPAFALGCLMLIPQSEKREQQIQAFLSTCNTETVLQQIDEHMNTGEVVAFASQIRSLILDSIINEKLYEKISKTKYFPLVKQQLMSTHRMKELVDYFANKNW", "length": 2186, "header": "tr|A0A8V1A3A1-1|A0A8V1A857_CHICK Computationally mapped isoform of Kinetochore associated 1 OS=Gallus gallus OX=9031 GN=KNTC1 PE=4 SV=1 CANONICAL=A0A8V1A857-1" }, "locus": { "chromosome": "15", "start_pos": 5955548, "end_pos": 5924052, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010062290.1", "url": "https://www.ensembl.org/id/ENSGALT00010062290.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038505.1", "url": "https://www.ensembl.org/id/ENSGALP00010038505.1" } ] } }, { "isoform_ac": "A0A8V1A857-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A857/entry#A0A8V1A857-1", "sequence": { "sequence": "MLVTMWNDIEILVNDDTRREQLSVCLGQECGSALYQVDSLLQITSSEKISVNPQLYACSSRDGSIIVVDRSVVLLDSTGQALQLHIQFDTNVDVVGMCQEKQFLVVGERSGNIHLVHIPSKKTLLTKILVETSSSEKTYLNLFIEKDTAVAGVYHMFILTDKGFFCIMCLPLAKTQEAINKMDMAAAMKLQGQIKTAFIATEEYHSLGCQNFVISNLANKIHMIIGGKGDYVLSKWEVDATNNLVSVRSFADSSLIKDAVKLQVLDNLLFVLDTENILSIWDVFSLTLIWDWPLIHVEEFLLTTESDSSSVMQQGLAGVKLIVMTTSTNKQMRSLMVFALPTMQQLYSLEVSIVSSLVLSGIGTDTIYFLEGIHENHQMPPEGPVSAVVMRSLTEALPENRLSRLLHKHKFTEAESFAIQFGLDVELVYKVKANTILEKLASASIGSYGQEVLLDYVNEAKENLHKIQDSQFVVDYCINAPWPLYETAQEMLNYAKVRILKKDDRTIVSPSDGTLVSLTEQVLRAQARLTTFYGAFGLEKFSGIAWTEFLNNEDVLKNILFQLEEGNLSCAQYLWLRHQADFEDTFDEKMLESLLNAIHVTVPLKELCLWLKNVVIPFLRRVVPKGQKVLAKWLEQGARNLELTDKANWPENGLQMAEIFFTSKNQDEMHLTSFGQWTPLKCSDCEEVHRLKKLVNDLQELTDLYRKYNCRLALCDFEKENTTTIVFRMFDKILAPELVPSILDKFIKPYLCEHNLQKDELLLQYIKDLLERCRTRSASVFETAWEAKAIAVTGCISDTDLKFDAVLQIMHGAVVPWSGAVEQLVKQHLEMNHVKVKLLQESYRLMEMKKLLRAYGIRDTNLLKDKEMIMRLVKYILKQDTPTSLEDALKMVEAYMLPTTEVYILRMIDLIDKERGEESLTLLKSLTTAEAEKVAERLTVWGRLVLQRKADNSEEQKTQMFMTKTLVEILKFLYKIQKDNPLKKDECEANLKTFNTLATLQEDFNIFLSVEDFGNPTLMSTLLEKHISAYETDKYPSKSRQEQTMNCKTKDGKLKNCSTESRLYRMALLLQRSEQELGTTLALRALGAGRVEDAVKICRNFYKNHCNKETGKLLFSTCQRLCHMLGGDVPMNTPEDMNLPAVIYEMACQAATICSPDLLLDSLELCKYTLAAKEIYRQCQIENYGFTAKTTCFGGDKDPYEEWTYNDFFNEDGIVLDSQIVLPVIYETISSLLPISENKLYPLDSTSLANCTFIRGQNLLLPARTPICAVLQNLMECSQCELALRLMVSSFGSCLQHGISNNMDLSLSEKLHDGNIQAETKSFLIAMKQTTASIITTSIMTLLHKVFNCRLIDQNLALGYCAILPREDMFNKLWGVINNTWQNYRKVLSVALVGAQLATQYGEAAEEKKFRELITDAEWGIQLGKFGISFETVFRQPPVRKKELIRTLVQNPEVGTDLILNYCRTFMLDSDAALQLCIETLLLKNANRNHAEDDSAEYSEKQSHYTLLARALEIIPLLKSTNDLVTSLSGILYKLDPYDYETIEIVLKVIQNADERNTSIHLNQALSLLKHLESYKRISPPVDLEHQYVSEHTIPLSPASETRLPFHLIFFRTAQCFWNIISAELSEESFPTLLLISKLMKVSLDTLHMSAAQHVFQKKLKPKIFEMRNTGYTSVVNKETTKTVQTIQSYLLSIINPEWAVAMAHKIAQEFPTGPDQIQALKFCLRLAEKWLKNTTAKDESHEKAEVLQKKLYMQYKRSATENVLITYKLNTAEYLKSIAKPANLIVLLYEHHSIDQRIQNPTGRDYPDIHMAAKEIAEINNLDMNKILNQLLNKWLCPNTLPSEKTQEIFADAQEDEELRRVIYLLQSHPMDYSSRMLFAITTSATSPIGINQLTFAHRSRALKCLLYLADTNTVESLFKKPIQKVKYFLKCFIYLAEFEVLNIPYTYESFHKSPKEGMIKGLWKNHSHEPTAVRLVTELSLEYKVYDFQLWNGLLQKLLGFNMIHYLRKVLIAITGIHSLWQIPSFSRAWRSVVLSPFLTASCPPSPKQIEECCECFVILLKCPVLADLDVIGIAKQYAQLDLPAFALGCLMLIPQSEKREQQIQAFLSTCNTETVLQQIDEHMNTGEVVAFASQIRSLILDSIINEKLYEKISKTKYFPLVKQQLMSTHRMKELVDYFANKNCIEDAAALIREYQEKYGNPTLLDKSSSDILKMYLNGPQETCVLELSSMKS", "length": 2235, "header": "tr|A0A8V1A857-1|A0A8V1A857_CHICK Isoform 1 of Kinetochore associated 1 OS=Gallus gallus OX=9031 GN=KNTC1 PE=4 SV=1 CANONICAL=A0A8V1A857-1" }, "locus": { "chromosome": "15", "start_pos": 5956166, "end_pos": 5924052, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010062292.1", "url": "https://www.ensembl.org/id/ENSGALT00010062292.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038506.1", "url": "https://www.ensembl.org/id/ENSGALP00010038506.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-141430", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-141430", "resource": "Reactome", "description": "Inactivation of APC/C via direct inhibition of the APC/C complex" }, { "id": "R-GGA-141444", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-141444", "resource": "Reactome", "description": "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" }, { "id": "R-GGA-2467813", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2467813", "resource": "Reactome", "description": "Separation of Sister Chromatids" }, { "id": "R-GGA-2500257", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2500257", "resource": "Reactome", "description": "Resolution of Sister Chromatid Cohesion" }, { "id": "R-GGA-5663220", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5663220", "resource": "Reactome", "description": "RHO GTPases Activate Formins" }, { "id": "R-GGA-9648025", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9648025", "resource": "Reactome", "description": "EML4 and NUDC in mitotic spindle formation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287AML8-1", "protein_name": "Kinetochore associated 1", "gene_name": "KNTC1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MWSDIELLTSDDTGSGYLSVGSRKEHGTALYQVDLLAKISSEKALLNPKIQACSLSDGFIIVADQSVILLDSVCRSLQLHLVFDTEVDVVGLCQEGKFLLVGERSGNLHLIHVTSKQTLLTNAFVQKANDENQRTYRNLVIEKDGSREGTYYMLLLTNNGFFCVTNLQLVKIQQAIEKVDFDTAKKLQGQIKSSFISTENYHTLDCLNLVAGDLASEVPVIIGGTGNCAFSKWEPDASRKGMTVKNVSDAEIIQGAKKFQLIDNLLFVLDTDNVLSLWDIYTLTPIWNWPSLHIEEFLLTTEADSPSSVTWQGITNLKLVALTTTTNKKIKNLMVYSLPVMEILYSLEVSSVSSLVQRGISTDTIYLLEGICKSDPRLSEDSVSVLVLRCLTEALPENRLSRLLHKHRFAEAESFAIQFGLDVELVYKVKANDILEKLALSSLDTHEQSKWQKLVNEAKENLHKIQDDEFVVNYCLEAQWITYETTQQMLNYAKNRLLKKEDKTIPVYSDGLKEVLRAHAKLTTFYGAFGPEKFSASSWIEFLNNEDDLRDIFLQLREGNLVCAQYLWLRHRAYFETRFDVKMLENLLNSISTPVSLQKLCPWLKNDVIPFVRRTIPKGQKILAKWLEQAARNLELTDKANWPENGLQLAEVFFTAEKPNELGLASSWRWSSLDYQNTEEVCQLRTLINNLRELITLHRKYNCKLALSDFEKENTTTIVFRMFDKVLAPELISSVFEKFIRVYMREHDLQEEELLLLYIEDLLKRCSSKSTSLFDTAWEAKAMAVIGCLSDTDLIFDAVLKIMYAAVVPWSAAVEQLVKQHLEMDHPKVKLLQESYKLMEMKKLLRGYGIREVNLLNKEIMRVVRYILKQDIPSSLEDALKVAEAYMLPKDEIYSLRIIDLIDREQGEDCILLLRSMAPAEAQKTAERVIIWAQLALQEEPDNSNEDKAWRMSIAKTSVDILKVLCDIQKDNLQKKDEWEETLKEFKSVVSLQENFEVFLSFGDYNNSSLVADLREQHIKALQDAQAKCRSQRPAEPTDTQKKRLHAEAKLHRQALALQVSRQELEFELTLRALNDGNVEAALRKCRDLFKYHRKADTGELLFLTCQKLCQMLAHGIPMTIPKGLNLPSEIHDLACQAATICSPDFLLDALELCKYTLTAVELSRQCQMDDCGILMKTSLGTHKDPYEEWSYSDFFSEDGIVLESHMVLPVIYELISSLVPLAESKRYPLDSTSLPYCSISEGNSLVLPVVSSISALLQNLQESSQWELALRFVVGSFGTCLQHSMSNFMNASLSEKLFGEATLVKSRDVVMELKEKAVTFIKGNATTLLYKVFNCRLVDHDLALGYCTLLPQKAVFENLWKLIDKAWQNYDKVLAISLVGSKLASLYQETEMELKFCELSTDAQWGIRLSKLGISFQPVFRQHFLTKKDLIKALVKNIDMDTSLILEYCSTFQLDSDAALQLFIETLLHNTNASQSQGDANTESTQEQRSKLLAKAIEMVPLLRSTKDLVISLSGILHKLDPYDYEMIEVVLKVIERADEKITNININQALSLLKHLKSYRRISPPVDLEYQYMLEHVITLPSAAQIRLPFHLIFFGTAQNFWKILSTELSEESFPTLLLISKLMKFSLDTLYVSTAKHVFEKKLKPKLLLLTQAKSSTLINKEITKITQTIESYLLSIVNPEWAVAIAISLAQDVPEGSFKMSSLKFCLYLAERWLQNIPSEDETHEKAEALLKKLHIQYRRSGTEAVLIAHKLNTTEYLRMIGKPAHLIVSLYEHPSINQRIQDSSGKDYPDIHAAAKEIAEVNEINLEKVWDMLLEKWLCPSTQPGEKPSELFELQEDEALRRVLYLLLSRPIDYSSRMLFIFATSATTTLGVHQLTYAHRTRALQCLLYLADKDTIESLFKKTIEEVKSYLKSITFLASFETLNIPITYELFCNSPKEGMIKGLWKNHSHESMAVKLVTELCLEYKIYDLPLWNGLLQKLLGFNMIPYLRKVLTAISSIHSLWQVPYFSKAWQRVIQIPLLSASCPLSPSQLSDCCESLIAVLECPVSDDLDLIRVARQYVQLDLPAFALACLMLMPHSEKRHQEIKNFLGSCDPQIVLQQLEEHMNTGRLAGFSHQIRSLVLNNIIDKKEFGILAKTKYFTVLKSHMMNTNSITELVNYLANELSLDEASVFITEYYKHCGKPVPPDATPCETLKMFLNGS", "length": 2207 }, "evidence": [ { "id": "A0A8V1A857", "url": "https://omabrowser.org/oma/group/A0A8V1A857/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8I6G9X6-1", "protein_name": "Kinetochore associated 1", "gene_name": "Kntc1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MWNNIELLTSDDTGSGFLNVGSRKESVTALYQVDLLGKISSEKTSLSPKIQACSLSDGFIIVADQSVILLDSTCRSLQLFLIFDTDVDVVGLCPEGKFLFVGERSGNFHLIYVTSKRTLFTKAFVEKAEDERTYRSLVIEKDGSNEGTYYMLLLTNNGFFYITNLQLSQIEQAIENTDLDSAKKLQGQFKCSFISTESYHSSGCLNLLASQSGKFANETSVIIGGTGSCAFSKWEPDSTKKDMSLKNFVDTDIIRGAKSFQLIDNLLFVLDTDNVLSLWDAYTLTPVWNWPSLPIEQFLLTTEADSPSSVTWQGITNLKLVTLTATTKEKMRNLIIYSLPTMEILYSLEVSSVSSLVQTGISTDTIYLLEGVHKNDPNLCEDSVSNLELRYLTEVLPENRLSRLLHKHRFADAESFAIQFGLDVELVYKVKSNDILEKLALISDKSEQSEWQQLVDEAKENLCKIQDDDFVVNFCLKAQWVTYETTQEMLSYAKTRLMKKEDRTLPACSDDFLEVLKAHAKLTTFYGAFGPEKFSGSAWVEFLNNEDDLKDIFVQLSEGNFDCAQYLWLRHRADFESKFDVKMLENLLNSISTQIPVEKLCSWFKNDVIPFVRRIVPEGQNILAKWLEQASRNLELTDKANWPENGLQLAEVFFTAEKTDKFGFSSSWHWISLKDYQNTEEVQQLRTLVSKLQELIILHRKYNCRLALSEFEKENATTVVFRMFDRVSAPELIPSVLEKFVRVYIREQNLQEEELLLLYIEDLLKRCSSKSMTLFDTAWEAKAMAVIRCLSDTDLIFDAVLKIMYKAVVPWSAAVEQLVRQHLEMDHPKVKLLQESYRLMEMKKLLRGYGIREVNLLNKEIMRVVRYILKQDIPSSLEDALKVAQGYRLSDDEIYSLRVIDLIDRDQGEDCLLLLRSLPPSEAEKTAERVIIWARLALQEEPDGSEEDKAWRISVAKTSMDILKILCDIQKDNLQKKDDAEEFLKRFKMVASLQENFEVFLPFEDYSDTGLVAGLREQYIKAQENAQAEHKFRGPPGPTPAMGTNASVKSKLHRQALVLQVSTQELEAEMALRALKDGKVAVALSKCRDLLKHYCNADTGRLLFVVCQKLCHMLADDVPMVAPVGLNLPSEIHDLTCHAVTICSPDFLLDVLELSKYTLTAVELCRQCQMDDCGILMKAAVGTHKDPYEEWSYSDFFSEDGIVLESQVVLPVIYELISSVVPLAEGKRRPLDSISLPYCSTSEGENLILPLVSSISALLRNLQESSQWELALRFVVASFGTCLQHSVSNVMSMSLSEKLLGKSTLASSRQIIMELKEKSIAFIRGSATTLLHKVFNCRLVDLDLALAYCTLLPQKDVFENLWKFIDKAWQNYDKILALSLVGSRLANLYQDVETGLRFHELSIDAKWGIRLGKLGISFQPAFRQNFLSKKDLIKALVNNIDMDTSLILEYCSTFQLDSDAALRLFIETLLRNTTSQSQGGDAPEPTQHQHSKLLQKATEMVPLLKSTKDLVISLTEILYKLDPYDYEMIEVVLKVIEQANEKITTVNINQALNLLRHLKSYRRMSPPVDLEYQYMLEHLITLPPAAQTRLPFHLILFGTAQNFWKILSSELSEESLPTLLLISKLMKFSLDTLYVSTAKHVFEKNLKPKLLKSAQARSSVMSKEVDKLVQTLESYLLSIVNPEWAVAIAISLTQEIPEGPFKMTSLKFCLYLAERWLQNIPPQDETCEKVKALQKKLYLQFRLSGTEAVLIAHKLNDQEYLRVVGKPAHLIVSLYEHPSISERLCTTSGKDYPDIHAAAKEIAEVNEINLEKIWDMLLEKWLCPSTAPGEKASEFFELEEDEVLHRVVYLLQARPIDYSSRMLFVFATSATSTLGIRQLTFAHRARALQCLLYLADKETIESLFKKPTEEMKSYLKCITFLASFETLNIPITYELFCNSPKEGMIKGLWKNHSHEPMAVRLVAELCLEYKIYDLQLWNGLLQKLLGFNMIPYLRKVLSCISSVHSLWQVPYFSKAWQRVIQIPLLSASCPLRPSQLADCCESLVAILECPVSDDLDMMGVAKQYVQLELPAFALTCLTLMPHSEKRHQQIKNFLNSCDAQIILQQLEEHMNAGQLAGLSQQIRSLVLNHVVNKKEFGILAKTKYFQLLKRHVINTDNVTELVNYLANDLSLDEASSLITEYSKHCGKPVPADTAPSEILKTFLGS", "length": 2205 }, "evidence": [ { "id": "A0A8V1A857", "url": "https://omabrowser.org/oma/group/A0A8V1A857/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1BBQ0-1", "protein_name": "Kinetochore associated 1", "gene_name": "KNTC1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MWNDIELLTNDDTGSGYLSVGSGKEHGTALYQVDLLAKISSEKASLNPKIQACSLSDGFIIIADQSVILLDSICRSLQLHLTFDTEVDVVGLCQEGKFLLVGERSGNLHLIHVTSKLTLLTNAFVQKANDENQCTYRNLVIEKDSSSEDTYYMLLLTNNGLFYITNLQLVKIQQAIEKADFDTAKKLQGQIKSSFISTENYHTLGCLNLVAGDLASEIPVIIGGTGNCALSKWEPDSSRKGMTVKSVIDSEIIKGAKKFQLIDNLLFVLDTDNVLSLWDIYTLTPIWNWPVLHVEEFLLTTEAESPSSVTWQGITNLKLVALTTTTNKKMKNLVVCSLPAMEILYSLEVSGISSLVQTGISTDTIYLLEGIFKNDPSLSEDSVSVLALRCLTEALPENRLSRLLHKHRFAEAESFAIQFGLDVELVYKVKSNDILEKLALSSLDTSEQTKWQKLVNEAKENLHKIQDDEFVMNYCLEAQWITYETTHEMLNYAKTRLLKKEDKTVLVYSDGLKEVLRAHAKLTTFYGAFGPEKFSGSSWIEFLNNEDDLKDIFLQLREGNLVCAQYLWLRHRANFESRFDVKMLENLLNSISTPISLQKLCPWLKNDVIPFVRKTVPEGQKILAKWLEQAARNLELTDKANWPENGLQLAEVFFTAENELGLASSWSWSSLDNQNMEEVCQLRTLVNNLRELITLHRKYNCKLALSDFEKEDTTTIVFRMFDKVLAPELIPSIFQKFIRVYMHEHDLQEEELLLLYIEDLLKRCSSKFTSLFDTAWEAKAMAVIGCLSDTDLIFDAVLKIMYAAVVPWSAAVEQLVKQHLEMGHPKVKLLQESYKLMEMKKLLRGYGIREVNLLNKEIMRVVRYILKQDVPSSLEDALKVAEAYMLPKDEIYSLRIIDLIDREQGEDCVLLLRSLPLAEAKKTAERVIIWARLALQEEPDTSNEDKAWRLSVAKTSVDILKILCNSQKDNLQKKDEWEETLKQFKTVASLQENFEVFLSFEDYSKSSLVAELREQHIKAHQVAQAKHKPWRPAEPRATEEQRLSAESKLHRQALTLQVSRQQLEAELTLRALSDGNVEAALRKCRDLFKYHCNTDTGQFLFLMCQKLCHMLASGVPMTVPVGLNLPSEIHDLACQAATICSPDFVLDALELCKYTLMAVELSRQCQMDDCGILTKTSFGTHKDPYEEWSYCDFFSEDGIVLESQMVLPVIYELISSLVPLAESKRYPLDSVSLPYCFTSEGDSLMLPVINSISALLQNLQESSQWELALKFVIGSFGTCLQHSVSSFMNASLSEKLFEEAPLVKSRHVVMELKEKAVMFIRGNATTLLYKVFNCRLVDLDLALGYCTLLPQKEVFENLWKLTDKAWQNYDKILAISLVGSQLASLCQETETKFKFCELSTDARWGIRLSKLGISFQPVFRQHFLTKNDLIKALVKNIDMDTSIILEYCSTFQLDADAALQLFIETLLHNTNASQSQGDVSTGSTKQQRSKLLAKALEMVPLLTSTKDLVISLSGILHKLDPYDYEMIEVVLKVIERADEKITNININQALSLLKHLKSYRRISPPVDLEHQYMLEHVITLPSAAQTRLPFHLIFFGTAQSFWKILSTELSEESFPTLLLVSKLMKFSLDTLYVSTAKHVFEKKLKPKLLQLTQGKSSTLINKEIAKITQTIESYLLSIVNPEWAVAIAISLAQDVPEGSFKMSSLKFCLYLAERWLQNIPSQDETREKAEALLKKLHVQYRRSGTEAVLIAHKLNTAEYLRVIGKPVHLIVSLYEHPSINQRIQNSCGKDYPDIHTAAKEIAEVNEINLEKVWDMLLEKWLCPSAKPDETPSELFELQEDETLRRVLYLLLSRPVDYSSRMLFIFATSATTMLRMHQLTFAHRTRALQCLLYLADKETIESLFKKSIEEVKSYLKCITFLASFEALNIPITYELFCNSPKEGMIKGLWKNHSHEPMAVKLVTELCLEYKIYDLQLWNGLLQKLLGFNMIPYLRKVLTAISSIYPLWQVPYFGRAWQCVVQIPLLSASCPLSPSQLSDCCESLIAVLECPVSDDLDMIRVARQYVQLELPAFALACLMLMPHSEKRHQEIKNFLSSCDPQIILQQLEEHMNTGQLAGFSHQIRSLVLKNIIDKKEFGILAKTKYFPVLKSHMMNTNNITELVNYLADELSLDDASVFITEYYKHCGKPIPPGTTPCETLKMFNGS", "length": 2204 }, "evidence": [ { "id": "A0A8V1A857", "url": "https://omabrowser.org/oma/group/A0A8V1A857/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P50748-1", "protein_name": "Kinetochore-associated protein 1", "gene_name": "KNTC1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MWNDIELLTNDDTGSGYLSVGSRKEHGTALYQVDLLVKISSEKASLNPKIQACSLSDGFIIVADQSVILLDSICRSLQLHLVFDTEVDVVGLCQEGKFLLVGERSGNLHLIHVTSKQTLLTNAFVQKANDENRRTYQNLVIEKDGSNEGTYYMLLLTYSGFFCITNLQLLKIQQAIENVDFSTAKKLQGQIKSSFISTENYHTLGCLSLVAGDLASEVPVIIGGTGNCAFSKWEPDSSKKGMTVKNLIDAEIIKGAKKFQLIDNLLFVLDTDNVLSLWDIYTLTPVWNWPSLHVEEFLLTTEADSPSSVTWQGITNLKLIALTASANKKMKNLMVYSLPTMEILYSLEVSSVSSLVQTGISTDTIYLLEGVCKNDPKLSEDSVSVLVLRCLTEALPENRLSRLLHKHRFAEAESFAIQFGLDVELVYKVKSNHILEKLALSSVDASEQTEWQQLVDDAKENLHKIQDDEFVVNYCLKAQWITYETTQEMLNYAKTRLLKKEDKTALIYSDGLKEVLRAHAKLTTFYGAFGPEKFSGSSWIEFLNNEDDLKDIFLQLKEGNLVCAQYLWLRHRANFESRFDVKMLESLLNSMSASVSLQKLCPWFKNDVIPFVRRTVPEGQIILAKWLEQAARNLELTDKANWPENGLQLAEIFFTAEKTDELGLASSWHWISLKDYQNTEEVCQLRTLVNNLRELITLHRKYNCKLALSDFEKENTTTIVFRMFDKVLAPELIPSILEKFIRVYMREHDLQEEELLLLYIEDLLNRCSSKSTSLFETAWEAKAMAVIACLSDTDLIFDAVLKIMYAAVVPWSAAVEQLVKQHLEMDHPKVKLLQESYKLMEMKKLLRGYGIREVNLLNKEIMRVVRYILKQDVPSSLEDALKVAQAFMLSDDEIYSLRIIDLIDREQGEDCLLLLKSLPPAEAEKTAERVIIWARLALQEEPDHSKEGKAWRMSVAKTSVDILKILCDIQKDNLQKKDECEEMLKLFKEVASLQENFEVFLSFEDYSNSSLVADLREQHIKAHEVAQAKHKPGSTPEPIAAEVRSPSMESKLHRQALALQMSKQELEAELTLRALKDGNIKTALKKCSDLFKYHCNADTGKLLFLTCQKLCQMLADNVPVTVPVGLNLPSMIHDLASQAATICSPDFLLDALELCKHTLMAVELSRQCQMDDCGILMKASFGTHKDPYEEWSYSDFFSEDGIVLESQMVLPVIYELISSLVPLAESKRYPLESTSLPYCSLNEGDGLVLPVINSISALLQNLQESSQWELALRFVVGSFGTCLQHSVSNFMNATLSEKLFGETTLVKSRHVVMELKEKAVIFIRENATTLLHKVFNCRLVDLDLALGYCTLLPQKDVFENLWKLIDKAWQNYDKILAISLVGSELASLYQEIEMGLKFRELSTDAQWGIRLGKLGISFQPVFRQHFLTKKDLIKALVENIDMDTSLILEYCSTFQLDCDAVLQLFIETLLHNTNAGQGQGDASMDSAKRRHPKLLAKALEMVPLLTSTKDLVISLSGILHKLDPYDYEMIEVVLKVIERADEKITNININQALSILKHLKSYRRISPPVDLEYQYMLEHVITLPSAAQTRLPFHLIFFGTAQNFWKILSTELSEESFPTLLLISKLMKFSLDTLYVSTAKHVFEKKLKPKLLKLTQAKSSTLINKEITKITQTIESCLLSIVNPEWAVAIAISLAQDIPEGSFKISALKFCLYLAERWLQNIPSQDEKREKAEALLKKLHIQYRRSGTEAVLIAHKLNTEEYLRVIGKPAHLIVSLYEHPSINQRIQNSSGTDYPDIHAAAKEIAEVNEINLEKVWDMLLEKWLCPSTKPGEKPSELFELQEDEALRRVQYLLLSRPIDYSSRMLFVFATSTTTTLGMHQLTFAHRTRALQCLFYLADKETIESLFKKPIEEVKSYLRCITFLASFETLNIPITYELFCSSPKEGMIKGLWKNHSHESMAVRLVTELCLEYKIYDLQLWNGLLQKLLGFNMIPYLRKVLKAISSIHSLWQVPYFSKAWQRVIQIPLLSASCPLSPDQLSDCSESLIAVLECPVSGDLDLIGVARQYIQLELPAFALACLMLMPHSEKRHQQIKNFLGSCDPQVILKQLEEHMNTGQLAGFSHQIRSLILNNIINKKEFGILAKTKYFQMLKMHAMNTNNITELVNYLANDLSLDEASVLITEYSKHCGKPVPPDTAPCEILKMFLSGLS", "length": 2209 }, "evidence": [ { "id": "A0A8V1A857", "url": "https://omabrowser.org/oma/group/A0A8V1A857/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8C3Y4-1", "protein_name": "Kinetochore-associated protein 1", "gene_name": "Kntc1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWNNIELLTSDDTGSGCLSVGSRKENVTALYQADLLGKISSEKTSLSPKIQAFSLSHGFIIVADQSVILLDSICRSLQLFLIFDTDVDVVGLCQEGKFLFVGERSGNFHLIYVTSKQTLFTKAFVEKALDESQRTYRNLIIEKDGSNEGTYYMLLLTNNGFFYITNLQLSQIEQAIENTDLDSAKKLQGQFKCSFISTENYHSCLSLVASQSGTFASKTSVIIGGTGSCAFSKWEPDSTKKEMSLKNFVGTDIIKGAKSFQLIDNLLFVLDTDNVLSLWDAYTLTPVWNWPSLPVEQFVLTTEADSPSSVTWQGITNLKLVTLTATAKEKMRSLIIYSLPSMETLYSLEVSSVSSLVQTGISTDTIYLLEGIHKNDPNLCEDSVSDLVLRYLTEVLPENRLSRLLHKHRFAEAESFAIQFGLDVELVYKVKSNDMLEKLALISSDKSEQSKWQQLVDEAKENLCKIQDDDFVVNFCLKAQWVTYETTQEMLSYAKTRLMKKEDRALPASSDAFMEVLKAHAKLTTFYGAFGPEKFSGSSWIEFLNNEDDLRDVFLQLSEGNFACAQYLWLRHRADFESKFDVKMLENLLNSISTQFPLENLCSWFKNEVIPFVRRIVPEGQNILAKWLEQASRNLELTDKANWPENGLQLAEVFFTAEKTDRFGFASSWHWISLDYQNTEEVRQLRTLVSKLRELIILHRKYNCKLALSDFEKENATTVVFRMFDRVSAPELIPSVLEKSVRVYIREQNLQEEELLLLYIEDLLKRCSSKSMTLFDTAWEAKAMAVIRCLSDTDLIFDAVLKIMYKAVVPWSAAVEQLVKQHLEMDHPKVKLLQESYKLMEMKKLLRGYGIREVNLLNKEIMRVIRYILKQDIPSSLEDALKVAQGYRLSDDEIYSLRIIDLIDREQGGDCLLLLKSLPAAEAEKTAERVIIWARLALQEEPDGSEEDKAWRISVAKTSVDILKILCDIRKDNLQKKDESEEFLKRFQMVASLQENFEVFLPFEDYSNTALVAGLREQYIKAQEAAQAEHKHRGPPGPTPARGTHLSIKSKLHRQALALQVSEQELEAELTLRALKDGKVVAALSKCRDLLKHYCNADTGRLLFVVCQKLCQMLADDVPMVAPGGLSLPSEIHDLACHAVTICSPDYLLDVLELSKYTLTAVELCRQCQMDDCGMLMKAALGTHKDPYEEWSFSDFFSEDGIVLESQVVLPVIYELISSVMPPAESKRHPLDSISLPYCSTSEGENRILPLVSSISALLRSLQECSQWELALRFVVGSFGTCLQHSMSNVMSISLSKQLLGKNTLANSRHIIMELKEKSITFIRENATTLLHKVFNCRVVDLDLALAYCTLLPQKDVFDNLWKFIDKAWQNYDKILALSLVGSQLANLYQDIETGLWFHELSIDAKWGIRLGKLGISFQPAFRQNFLTKKDLIKALVNNIDMDTSLILEYCSTFQLDSDAALRLFIETLLRNTSSQSQGDAAPESTKHQHSKLLAKATELVPLLKNTKDLVISLSEILYKLDPYDYEMIDVVLKVLEQANEKITSVNINQALNLLRHLKSYRRISPPVDHEYQYALEHMITLPPAAHTRLPFHLILFGTAQNFWKILSSELSEESLPTLLLIAKLMKFSLDTLYVSTAKHLFEKNLKPKLLKSAQARSSTLMSKEVDKLMQTLESYLLSIVNPEWAVAIAISLTQEVPEGPFKMSSLKFCLYLAERWLQNIPPQDETCEKAKALQKKLCLQVRLSGTEAVLIAHKLNDQEYLRVIGKPAHLIVSLYEHPSISERLCTTSGKDYPDIHTAAKEIAEVNEVNLEKIWDMLLEKWLCPSTVPSEKASEFFELEEDEVLHRVVYLLQARPVDYCSRMLFVFATSATSTLGMRQLTFAHKARALQCLLYLADKETIESLFKKPIKEMKSYLKCITFLASFETLNIPITYELFCNSPKEGMIKGLWKNHSHEPMAVRLVAELCLEYKIYDLQLWNGLLQKLLGFNMIPYLRKVLSCISSIHSLWQVPYFSKAWQRVIQIPLLSASCPLRPSQLADCCDSLVAILECPVSDDLDMMGVAKQYVQLDLPAFALTCLTLMPHSEKRHQQIKNFLNSCDARIILQQIEEHMNTGQLAGFSHQIGSLVLNHVVNKKEFGILAKTKYFQLLKCHVINTGNVTELVNYLANDFSVDEASALINEYSKHCGKPVPADAAPCEILQTFLGGS", "length": 2207 }, "evidence": [ { "id": "A0A8V1A857", "url": "https://omabrowser.org/oma/group/A0A8V1A857/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9V9W7-1", "protein_name": "Rough deal", "gene_name": "rod", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MWSNFEASSLEDETISNIFSSRGIFQISSEEEVNKYPDVMASVQCGKMVIGIDKSLLLLEDELVAKCSFLAFGAAIEAIAISSSGNLIVCGLSDGEVHGVFIKGLLLFSVAVNLEDVSLTGGTFRSIHQLDQRFYFTCKNGSIYSLSDIDETCLETLGNMSLNENETIACEKALLEDVTIQRLSKGRSSCSVDCAVLLKRLLTGNISAENNQDDLEAQPGLVITGDQSTMNFRNAANDVTRINLPAQYGSLKQIFNLEHYIIALTDSGHLVEICPYTRTVYMCQTTQQKNLLIEDLLVMECSEDNIELLVLTKSTAEGRFIKIVEYPTLNVKNEVEVPDHAWLVRQPKCAVNLYYLAAKEVNQSSIPSVVEMMLVSETDPSDRFKKLICKGRLEEAEEFGKQFELCLQPIYEAKAKRILVELCNSNSQNVDTKFQDLLQLLSQVESKAFIKSHRMINLNSRHILERYLHEVKKRLTFEDDEEDMLEIDEQLHRLKTLAIIDPYECNTDWQKFIYDNNLVRMVKSLFNTDMPTACLIWRRHSSSILPLLNEDELRTLLGFIPSNTKPFNVVQWLRQFIPMVSNTHPSIMPFITDWSIEMTRNLQYSPHWPDIGLEFCTKILDIFEEIQFTYSDVRRQQERNVGKLRDLVNALQDLSVLKTNYNMGFTLDNYMQDSIDATALSILQHVQLDKLQRLVKNFMYPIFQEKGRQPLDVIKQYISQLVASRLSSSSWLDRAMACIELLHNEDSRLECALSVLQNAPVPWPDTLAPLIRLRASTHPLAVKINAEYEIQVIKIMKVKYGWPADSSDINLELFMMRIVKLNLPDMLDDISALTKAAPELSTSANFNCCYQMARRGQVEMAYEFFKKLNGEKNSKSAKEVVEIMANILENSSSASFESDIKVQEHLNVLELFKLFLPHVESVYERRYLVIKHRFRLRKFGILLSCSSELIPLHRRHCLLDEAIERIIERAQATLNVSAFIASEISELCTALGLPKVFGLHRICQRIGCLPLSCALAYHVVSFVDCVPANAGEFVNLALELLVQQIESAKGKNQETASSLQLINENDPLSFYLAYELLTSALLHESSRRHDLVELIKYIRVAVIHYPLDAIKSHYDGKEQAVNEHICRALDGISVALGETTINFSCALNGSFDVKTLTVPTTTKKRYSVSMFDEVEVQPIQQQPQKKSVGGRMAIVKFLARTLLLMVIETEPNNSLLMQVRNELPENTKADVESACADFFLSLEHLTKVKEHDAWYVMSQYLLDFQKQNCRTKRIINEGFITLQLRRIFRNAMGSKDVNFIELFTMLVVDSEALALLEKLSVEVKTDLQKINFLTLSAMYHEHIEDLDSVHMIRTKRLKLFYYLEFCQQDHRIKGKFNADMDNIEDLLKEFHNKQLDVQLLERMSKDFGFDYQKILITQILSILSAQELRFEVKRDTFGDEELVMLSSAQEMRDMCQPYINEINNVELFTSKLKHFIEDINIYFYELYMCVINILMYFDSAPKEMEIWMNILHFLRHKMITRRRNRPGQVETDTWLKSQRENGVMPKISRYRLPFKPIVEQPLKDILDSELNVDNCQSWFPLIQMYTALKGSKDSSQNCDYFCMSAVKNSISEYKSKNDSESWSLHPTNNAFLQSILRLVEKVNNPNKAFLILYFVSNYARDGADQVEASYECWKFVKEKGHLITDPKSREQVAKVKRRYPIQKTQHLLYVYGLTDEKLLRQVENPTELIQALYHHELILKSSKVDINALVAEIAKLHDLCLATIQYRLLQKWLALTMESAGDGTILEETFMEEQNWPEQANGAESSNSQDASENVNRAFYILSSWPKAEAVKFLVGLIFKGGSVNTSTQLQMYECYSKLNDGSNSFTNTISQRQFISIKCVHELKALGYKSNLEKFSDDHCNKIDILKMIWQRNAQNPLSLEVMANICLGFDIHLPQIWNGILKRMVMFHMVRELNALLDVLSCRPHLLHLDGLAQAWDYVLCHPLQNAVELRSFKQEEVLHKTLLRLQGCPVVHALNLLQFAQLCIVVHRPHMAASLLSFCQSSEQRQKIKKMIHSHPVENLRQQILDLEDAGILPVVLNFALKELNL", "length": 2089 }, "evidence": [ { "id": "A0A8V1A857", "url": "https://omabrowser.org/oma/group/A0A8V1A857/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "kinetochore microtubule", "id": "GO:0005828", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005828", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A857", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A857" } ], "pmid": "" }, { "name": "RZZ complex", "id": "GO:1990423", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990423", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A857", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A857" } ], "pmid": "" }, { "name": "spindle pole", "id": "GO:0000922", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000922", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A857", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A857" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A857", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A857" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A857", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A857" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "protein localization to kinetochore involved in kinetochore assembly", "id": "GO:1903394", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903394", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A857", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A857" } ], "pmid": "" }, { "name": "mitotic spindle assembly checkpoint signaling", "id": "GO:0007094", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007094", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A857", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A857" } ], "pmid": "" }, { "name": "mitotic sister chromatid segregation", "id": "GO:0000070", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000070", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A857", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A857" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A857", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A857" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1056, "end_pos": 1058, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1250, "end_pos": 1252, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1378, "end_pos": 1380, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1557, "end_pos": 1559, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1734, "end_pos": 1736, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1967, "end_pos": 1969, "annotation": "n_glycosylation_sequon" }, { "start_pos": 567, "end_pos": 569, "annotation": "n_glycosylation_sequon" }, { "start_pos": 721, "end_pos": 723, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1A857", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A857" }, { "id": "PF24506", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24506" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "KNTC1 N-terminal", "eco_id": "ECO_0000259", "start_pos": 27, "end_pos": 395, "start_aa": "Gly", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1A857", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A857" }, { "id": "PF24520", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24520" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "KNTC1 first ARM-repeats", "eco_id": "ECO_0000259", "start_pos": 404, "end_pos": 654, "start_aa": "Arg", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1A857", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A857" }, { "id": "PF24516", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24516" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "KNTC1 second ARM-repeats", "eco_id": "ECO_0000259", "start_pos": 760, "end_pos": 926, "start_aa": "Glu", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1A857", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A857" }, { "id": "PF24515", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24515" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "KNTC1 third ARM-repeats", "eco_id": "ECO_0000259", "start_pos": 1338, "end_pos": 1548, "start_aa": "Ser", "end_aa": "Lys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1A857", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A857" }, { "id": "PF10493", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10493" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RZZ complex subunit KNTC1/ROD C-terminal", "eco_id": "ECO_0000259", "start_pos": 1594, "end_pos": 2143, "start_aa": "Ile", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1056, "end_pos": 1058 }, { "start_pos": 1250, "end_pos": 1252 }, { "start_pos": 1378, "end_pos": 1380 }, { "start_pos": 1557, "end_pos": 1559 }, { "start_pos": 1734, "end_pos": 1736 }, { "start_pos": 1967, "end_pos": 1969 }, { "start_pos": 567, "end_pos": 569 }, { "start_pos": 721, "end_pos": 723 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": 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}, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A881-1", "uniprot_ac": "A0A8V1A881", "uniprot_id": "A0A8V1A881_CHICK", "mass": { "chemical_mass": 50815.0, "monoisotopic_mass": 50815.0 }, "refseq": {}, "gene_names": [ { "name": "IP6K3", "type": "recommended", "evidence": [ { "id": "A0A8V1A881", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A881" } ] } ], "protein_names": [ { "name": "Kinase", "type": "recommended", "evidence": [ { "id": "A0A8V1A881", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A881/entry#names_and_taxonomy" } ] }, { "name": "2.7.-.-", "type": "synonym", "evidence": [ { "id": "A0A8V1A881", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A881/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A881", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A881" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "IP6K3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A881", "locus": { "chromosome": "26", "start_pos": 4654706, "end_pos": 4640406, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027265", "url": "https://www.ensembl.org/id/ENSGALG00010027265" } ] } } ], "crossref": [ { "id": "A0A8V1A881", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A881", "database": "AlphaFoldDB", "categories": [] }, { "id": "419908", "url": "https://www.ncbi.nlm.nih.gov/gene/419908", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR005522", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005522", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038286", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038286", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:419908", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419908", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VYQADTG", "url": "https://omabrowser.org/oma/group/VYQADTG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A3A4", "url": "https://www.orthodb.org/?gene=A0A8V1A3A4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A881", "url": "https://www.orthodb.org/?gene=A0A8V1A881", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ADM5", "url": "https://www.orthodb.org/?gene=A0A8V1ADM5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12400", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12400", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12400:SF40", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12400:SF40", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03770", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03770", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-1855167", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1855167", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1A3A4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3A4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A3A4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3A4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A881", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A881", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A881-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A881-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ADM5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADM5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ADM5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADM5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLLPTPLVLCMHQNKAAVISLWSHCTRETECGHASNTPTRGSLSPNLTPRLCFPLTPGAVFSPSQPQLSAGHTGALPEMLQCQLTAQMSAGSPCSFISHPRATLSSSEIPEPAVGPAGVVSVHLKKDSFGNLTLLASPSLQPEGCGRLDNTSSDIWHKYKWAASASSSTELVKRCHTQLTKTFKDSCPGRMRLRTDLQYCTDSLLEDANRNQTEKNSSNPWGLHCHRQHLNRMSSKYNENKLHQFLLLENVVSKYNYPCILDLKMGTRQHGDDASEEKKARHIKKCEQSTSASLGVRVCGMQVYQADAGHFLCKDKYYGRKLSPEGFRQTLQQFLCNGNHLRTDVLEPIILKLKALLSVIKKQSSYRFYSSSLLIIYDGLEHKESTAPLDNHLQGHFQKTNCTTSHSRVDVRMIDFAHTTFKGSKCNHTTYDGPDHGYIFGLENLIKILQNISEGK", "length": 456, "header": "tr|A0A8V1A881-1|A0A8V1A881_CHICK Isoform 1 of Kinase OS=Gallus gallus OX=9031 GN=IP6K3 PE=3 SV=1 CANONICAL=A0A8V1A881-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A3A4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A881/entry#A0A8V1A3A4-1", "sequence": { "sequence": "MVGQSEGKRAVLLEPFVHQVGGHMSMMKYDEHTVCKPLVSQELSFYESLPLAMRQFTPQYKGVVSVHLKKDSFGNLTLLASPSLQPEGCGRLDNTSSDIWHKYKWAASASSSTELVKRCHTQLTKTFKDSCPGRMRLRTDLQYCTDSLLEDANRNQTEKNSSNPWGLHCHRQHLNRMSSKYNENKLHQFLLLENVVSKYNYPCILDLKMGTRQHGDDASEEKKARHIKKCEQSTSASLGVRVCGMQVYQADAGHFLCKDKYYGRKLSPEGFRQTLQQFLCNGNHLRTDVLEPIILKLKALLSVIKKQSSYRFYSSSLLIIYDGLEHKESTAPLDNHLQGHFQKTNCTTSHSRVDVRMIDFAHTTFKGSKCNHTTYDGPDHGYIFGLENLIKILQNISEGK", "length": 400, "header": "tr|A0A8V1A3A4-1|A0A8V1A881_CHICK Computationally mapped isoform of Kinase OS=Gallus gallus OX=9031 GN=IP6K3 PE=3 SV=1 CANONICAL=A0A8V1A881-1" }, "locus": { "chromosome": "26", "start_pos": 4653596, "end_pos": 4645626, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066097.1", "url": "https://www.ensembl.org/id/ENSGALT00010066097.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040363.1", "url": "https://www.ensembl.org/id/ENSGALP00010040363.1" } ] } }, { "isoform_ac": "A0A8V1A881-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A881/entry#A0A8V1A881-1", "sequence": { "sequence": "MLLPTPLVLCMHQNKAAVISLWSHCTRETECGHASNTPTRGSLSPNLTPRLCFPLTPGAVFSPSQPQLSAGHTGALPEMLQCQLTAQMSAGSPCSFISHPRATLSSSEIPEPAVGPAGVVSVHLKKDSFGNLTLLASPSLQPEGCGRLDNTSSDIWHKYKWAASASSSTELVKRCHTQLTKTFKDSCPGRMRLRTDLQYCTDSLLEDANRNQTEKNSSNPWGLHCHRQHLNRMSSKYNENKLHQFLLLENVVSKYNYPCILDLKMGTRQHGDDASEEKKARHIKKCEQSTSASLGVRVCGMQVYQADAGHFLCKDKYYGRKLSPEGFRQTLQQFLCNGNHLRTDVLEPIILKLKALLSVIKKQSSYRFYSSSLLIIYDGLEHKESTAPLDNHLQGHFQKTNCTTSHSRVDVRMIDFAHTTFKGSKCNHTTYDGPDHGYIFGLENLIKILQNISEGK", "length": 456, "header": "tr|A0A8V1A881-1|A0A8V1A881_CHICK Isoform 1 of Kinase OS=Gallus gallus OX=9031 GN=IP6K3 PE=3 SV=1 CANONICAL=A0A8V1A881-1" }, "locus": { "chromosome": "26", "start_pos": 4653596, "end_pos": 4641646, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066099.1", "url": "https://www.ensembl.org/id/ENSGALT00010066099.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040365.1", "url": "https://www.ensembl.org/id/ENSGALP00010040365.1" } ] } }, { "isoform_ac": "A0A8V1ADM5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A881/entry#A0A8V1ADM5-1", "sequence": { "sequence": "MLQCQLTAQMSAGSPCSFISHPRATLSSSEIPEPAVGPAGVVSVHLKKDSFGNLTLLASPSLQPEGCGRLDNTSSDIWHKYKWAASASSSTELVKRCHTQLTKTFKDSCPGRMRLRTDLQYCTDSLLEDANRNQTEKNSSNPWGLHCHRQHLNRMSSKYNENKLHQFLLLENVVSKYNYPCILDLKMGTRQHGDDASEEKKARHIKKCEQSTSASLGVRVCGMQVYQADAGHFLCKDKYYGRKLSPEGFRQTLQQFLCNGNHLRTDVLEPIILKLKALLSVIKKQSSYRFYSSSLLIIYDGLEHKESTAPLDNHLQGHFQKTNCTTSHSRVDVRMIDFAHTTFKGSKCNHTTYDGPDHGYIFGLENLIKILQNISEGK", "length": 378, "header": "tr|A0A8V1ADM5-1|A0A8V1ADM5_CHICK Computationally mapped isoform of Kinase OS=Gallus gallus OX=9031 GN=IP6K3 PE=3 SV=1 CANONICAL=A0A8V1A881-1" }, "locus": { "chromosome": "26", "start_pos": 4653596, "end_pos": 4641880, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066100.1", "url": "https://www.ensembl.org/id/ENSGALT00010066100.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040366.1", "url": "https://www.ensembl.org/id/ENSGALP00010040366.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:419908", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419908", "resource": "KEGG Pathway" }, { "id": "R-GGA-1855167", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1855167", "resource": "Reactome", "description": "Synthesis of pyrophosphates in the cytosol" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8D0NWE3-1", "protein_name": "Kinase", "gene_name": "IP6K3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "PCTGNGSARTRCAWLLCLKHEGAEQGVHAEAVWTWAQGHLLQASWLWVHPNQDRAQAAPERVLERSGGEADQCHETAVQQDVTGTITVHLQKDSRGRLSLVANPLKENRGPLKVTEESTAVAIWQTLQQTCGGGGGLPVAQWEHTQPAHAVKDSPATALLRSELHLKAQVSPLLGDADGSQAEKRGFNPWGLHCHQAHLSRLCAEYPENQRHRFLLLENIVSQYKHPCILDLKMGTRQHGDDASEEKKARHAKKCAQSTSARLGLRICGMQVYQADKKHFLCKDKYYGRKLSVEGFRQALCQFLHDGTRLRTELLEPMQHQLQALLSVIRSQSSYRFYSSSLLITYDGQEAAPSSSDTLAKVDVRMIDFAHTTYKGSWNERATYDGPDLGYIFGLENLIQILRDIQEGA", "length": 409 }, "evidence": [ { "id": "A0A8V1A881", "url": "https://omabrowser.org/oma/group/A0A8V1A881/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A9J7F1G0-1", "protein_name": "Kinase", "gene_name": "Ip6k3", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MLVDRGGHREASVPTTCALTPPEGGSDKWAVRSHLSWDSGKGCNRQRSGTTDSPPGGNSSFCVLPSSGGLGGAMVVLHSTDKGNNGVGVPLEPFLHQVGGHMSMLQYDAHTVCKPLISQEQKFYESLPMAMRCFTPQYKGTVTVCLRRDSRGHLGLVANPLKENLEPLQVSPDSRAVAIWQTLQQSASSNSSPRPLAQLACSLKESTTKVLLSSDCHLSAQAPPLAESADGSQVERRDFNPWGLHCHQAHLTRLCSEYPEDKRHRFLLLENVVSQYKQPCILDLKMGTRQHGDDASEEKKVRHMRKCAQSTSACLGVRICGMQVYQTDKKSFLCKDKYYGRKLSEKGFRQALSQFLHDGTRLRTELLEPILRRLQALLAVIRSQSSYRFYSSSLLIIYDGQEPPQNALETTPGTTSGDPAKVDVRMIDFAHTTYKGSWNGHTTHEGPDPGYIFGLENLIGILQDIQEGD", "length": 469 }, "evidence": [ { "id": "A0A8V1A881", "url": "https://omabrowser.org/oma/group/A0A8V1A881/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "D4AEE6-1", "protein_name": "Kinase", "gene_name": "Ip6k3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVVRHGSDKGKAGVGVPLEPFLHQVGGHLSVLRYDAYTVCKPLIFQEQKFYESLPLAMRRFTPQYKGTITVHLRRDSRGHLGLVANPLKENLEPFQVSPESRAVALWQTLQQTTSSEGSPCPLAQMAHSLKESAAKALLRSDCHLSTQASPLVESAVGSQIERKGFNPWGLHCHQAHLSRLCSQYPEDKRHRFLLLENVVSQYKQPCILDLKMGTRQHGDDASEEKKARHMKKCAQSTSACLGVRICGMQVYQTDKKSFLCKDKYYGRKLSVEGFRQALSQFLHDGIRLRTELLEPILRRLQALLTVIRSQSSYRFYSSSLLIIYDGEPPQTAPAPQTTQGSTSGSTSGDPAKVDVRMIDFAHTTYKGSWNERTTYEGPDPGYIFGLENLIGILRDIQEGE", "length": 401 }, "evidence": [ { "id": "A0A8V1A881", "url": "https://omabrowser.org/oma/group/A0A8V1A881/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1MQ28-1", "protein_name": "Kinase", "gene_name": "IP6K3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MVVQDNVDAPGVPLEPFLHQVGGHLSVMRYDEHTVCKPLISREQRFYESLPLAMKRFTPQYKGTITVHLQKDSRGRLSLVANPLTENRGPFTVSTESAAVAIWQTLQQTTGGSALPLAQWQHPQRAHSLKESPATALLRSELHLKAQVPSLVEDANGNLTEKGSFNPWGLHCHQAHLSRLCAEYPENKRHRFLLLENVVSQYKHPCILDLKMGTRQHGDDASEEKKARHMRKCAQSTSAHLGMRICGMQVYQTDKKHFLCKDKYFGRKLSVEGFRQALYQFLHDGTRFRMELLEPIQHQLQALLSVIRSQSSYRFYSSSLLIIYDGQETPQTPHGSSVIKVDVRMIDFAHTTYKGSWNEHTTYDGPDPGYIFGLENLIQILQRIHEGQ", "length": 388 }, "evidence": [ { "id": "A0A8V1A881", "url": "https://omabrowser.org/oma/group/A0A8V1A881/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8BWD2-1", "protein_name": "Inositol hexakisphosphate kinase 3", "gene_name": "Ip6k3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVVRHSSDKGKIGVGVPLEPFLHQVGGHLSVLQYDAYTVCKPLVSQEQKFYESLPLAMKCFTPKYKGTITVRLRRDSRGHLGLVANPLKENLEPFQVSPESRAVALWQTLQQTTGSESSPCPLTQLARSLKESAAKVLLRSDCHLSTQASPLVESEDGSQVERKGFNPWGLHCHQAHLTRLCSQYPEDKRHRFLLLENVVSQYKQPCILDLKMGTRQHGDDASEEKKARHMKKCAQSTSACLGVRICGMQVYQTDQKSFLCKDKYYGRKLSVEGFRQALSQFLHDGTRLRAELLEPILRRLQALLTVIRSQSSYRFYSSSVLIIYDGEPPQTTQGSTSGGVTSGDPAKVDVRMIDFAHTTFKGSWNEHTTYEGPDPGYIFGLENLIGILRDIQEGE", "length": 396 }, "evidence": [ { "id": "A0A8V1A881", "url": "https://omabrowser.org/oma/group/A0A8V1A881/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96PC2-1", "protein_name": "Inositol hexakisphosphate kinase 3", "gene_name": "IP6K3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVVQNSADAGDMRAGVQLEPFLHQVGGHMSVMKYDEHTVCKPLVSREQRFYESLPLAMKRFTPQYKGTVTVHLWKDSTGHLSLVANPVKESQEPFKVSTESAAVAIWQTLQQTTGSNGSDCTLAQWPHAQLARSPKESPAKALLRSEPHLNTPAFSLVEDTNGNQVERKSFNPWGLQCHQAHLTRLCSEYPENKRHRFLLLENVVSQYTHPCVLDLKMGTRQHGDDASEEKKARHMRKCAQSTSACLGVRICGMQVYQTDKKYFLCKDKYYGRKLSVEGFRQALYQFLHNGSHLRRELLEPILHQLRALLSVIRSQSSYRFYSSSLLVIYDGQEPPERAPGSPHPHEAPQAAHGSSPGGLTKVDIRMIDFAHTTYKGYWNEHTTYDGPDPGYIFGLENLIRILQDIQEGE", "length": 410 }, "evidence": [ { "id": "A0A8V1A881", "url": "https://omabrowser.org/oma/group/A0A8V1A881/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "kinase activity", "id": "GO:0016301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016301", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A881", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A881" } ], "pmid": "" }, { "name": "inositol hexakisphosphate kinase activity", "id": "GO:0000828", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000828", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A881", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A881" } ], "pmid": "" }, { "name": "inositol hexakisphosphate 6-kinase activity", "id": "GO:0000831", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000831", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A881", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A881" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "inositol phosphate biosynthetic process", "id": "GO:0032958", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032958", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A881", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A881" } ], "pmid": "" }, { "name": "phosphatidylinositol phosphate biosynthetic process", "id": "GO:0046854", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046854", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A881", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A881" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A881", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A881" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A881", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A881" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 131, "end_pos": 133, "annotation": "n_glycosylation_sequon" }, { "start_pos": 150, "end_pos": 152, "annotation": "n_glycosylation_sequon" }, { "start_pos": 211, "end_pos": 213, "annotation": "n_glycosylation_sequon" }, { "start_pos": 216, "end_pos": 218, "annotation": "n_glycosylation_sequon" }, { "start_pos": 401, "end_pos": 403, "annotation": "n_glycosylation_sequon" }, { "start_pos": 427, "end_pos": 429, "annotation": "n_glycosylation_sequon" }, { "start_pos": 451, "end_pos": 453, "annotation": "n_glycosylation_sequon" }, { "start_pos": 46, "end_pos": 48, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-GGA-1855158", "name": "5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/3 in the cytosol", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-ALL-1629765" ], "output_participant_list": [ "R-ALL-1629759" ], "enzyme_list": [ "A0A8V1A6L5-1", "A0A8V1A881-1" ], "evidence": [ { "id": "R-GGA-1855158", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1855158" } ] }, { "id": "R-GGA-1855193", "name": "1-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/3 in the cytosol", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-ALL-1629736" ], "output_participant_list": [ "R-ALL-1629738" ], "enzyme_list": [ "A0A8V1A6L5-1", "A0A8V1A881-1" ], "evidence": [ { "id": "R-GGA-1855193", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1855193" } ] }, { "id": "R-GGA-1855194", "name": "1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-ALL-1629740" ], "output_participant_list": [ "R-ALL-1629732" ], "enzyme_list": [ "A0A8V1A6L5-1", "A0A8V1A881-1" ], "evidence": [ { "id": "R-GGA-1855194", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1855194" } ] }, { "id": "R-GGA-1855223", "name": "I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/3 in the cytosol", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-ALL-994141" ], "output_participant_list": [ "R-ALL-1629755" ], "enzyme_list": [ "A0A8V1A6L5-1", "A0A8V1A881-1" ], "evidence": [ { "id": "R-GGA-1855223", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1855223" } ] }, { "id": "R-GGA-1855227", "name": "IP6 is phosphorylated to 5-PP-IP5 by IP6K1/3 in the cytosol", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-ALL-1629770" ], "output_participant_list": [], "enzyme_list": [ "A0A8V1A6L5-1", "A0A8V1A881-1" ], "evidence": [ { "id": "R-GGA-1855227", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1855227" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-1629732", "participant_name": "1,5-(PP)2-IP4 [cytosol]", "crossref": [ { "id": "ZINC000096085264", "database": "ZINC", "url": "" }, { "id": "77983", "database": "ChEBI", "url": "" } ] }, { "participant_id": "R-ALL-1629736", "participant_name": "1-PP-IP4 [cytosol]", "crossref": [ { "id": "62926", "database": "ChEBI", "url": "" }, { "id": "ZINC000087528190", "database": "ZINC", "url": "" } ] }, { "participant_id": "R-ALL-1629738", "participant_name": "1,5-(PP)2-IP3 [cytosol]", "crossref": [ { "id": "62931", "database": "ChEBI", "url": "" }, { "id": "ZINC000087528210", "database": "ZINC", "url": "" } ] }, { "participant_id": "R-ALL-1629740", "participant_name": "1-PP-IP5 [cytosol]", "crossref": [ { "id": "74946", "database": "ChEBI", "url": "" }, { "id": "ZINC000095630287", "database": "ZINC", "url": "" } ] }, { "participant_id": "R-ALL-1629755", "participant_name": "5-PP-IP4 [cytosol]", "crossref": [ { "id": "62928", "database": "ChEBI", "url": "" }, { "id": "ZINC000087528195", "database": "ZINC", "url": "" } ] }, { "participant_id": "R-ALL-1629759", "participant_name": "5-PPP-IP5 [cytosol]", "crossref": [ { "id": "62985", "database": "ChEBI", "url": "" }, { "id": "ZINC000096085270", "database": "ZINC", "url": "" } ] }, { "participant_id": "R-ALL-1629765", "participant_name": "5-PP-IP5 [cytosol]", "crossref": [ { "id": "58628", "database": "ChEBI", "url": "" }, { "id": "ZINC000085552707", "database": "ZINC", "url": "" }, { "id": "C11526", "database": "COMPOUND", "url": "" } ] }, { "participant_id": "R-ALL-1629770", "participant_name": "IP6 [cytosol]", "crossref": [ { "id": "58130", "database": "ChEBI", "url": "" }, { "id": "ZINC000169289809", "database": "ZINC", "url": "" }, { "id": "C01204", "database": "COMPOUND", "url": "" } ] }, { "participant_id": "R-ALL-994141", "participant_name": "I(1,3,4,5,6)P5 [cytosol]", "crossref": [ { "id": "57733", "database": "ChEBI", "url": "" }, { "id": "ZINC000100015963", "database": "ZINC", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A8V1A6L5", "gene_name": "IP6K1", "activity": [ { "ec_number": "2.7.-.-", "activity": "", "evidence": [ { "id": "A0A8V1A6L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6L5" } ] } ] }, { "uniprot_ac": "A0A8V1A881", "gene_name": "IP6K3", "activity": [ { "ec_number": "2.7.-.-", "activity": "", "evidence": [ { "id": "A0A8V1A881", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A881" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 131, "end_pos": 133 }, { "start_pos": 150, "end_pos": 152 }, { "start_pos": 211, "end_pos": 213 }, { "start_pos": 216, "end_pos": 218 }, { "start_pos": 401, "end_pos": 403 }, { "start_pos": 427, "end_pos": 429 }, { "start_pos": 451, "end_pos": 453 }, { "start_pos": 46, "end_pos": 48 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A8I0-1", "uniprot_ac": "A0A8V1A8I0", "uniprot_id": "A0A8V1A8I0_CHICK", "mass": { "chemical_mass": 79884.0, "monoisotopic_mass": 79884.0 }, "refseq": { "ac": "XP_015153780", "name": "tetratricopeptide repeat protein 12 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015153780" }, "gene_names": [ { "name": "TTC12", "type": "recommended", "evidence": [ { "id": "A0A8V1A8I0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8I0" } ] }, { "name": "TTC12", "type": "synonym", "evidence": [ { "id": "XP_015153780", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015153780" } ] } ], "protein_names": [ { "name": "Tetratricopeptide repeat domain 12", "type": "synonym", "evidence": [ { "id": "A0A8V1A8I0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8I0/entry#names_and_taxonomy" } ] }, { "name": "tetratricopeptide repeat protein 12 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015153780", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015153780" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052555.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015153780.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015153780", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015153780" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A8I0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8I0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TTC12", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8I0", "locus": {} } ], "crossref": [ { "id": "A0A8V1A8I0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A8I0", "database": "AlphaFoldDB", "categories": [] }, { "id": "770784", "url": "https://www.ncbi.nlm.nih.gov/gene/770784", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013105", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013105", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019734", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019734", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043195", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043195", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:770784", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:770784", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "AVQQNCA", "url": "https://omabrowser.org/oma/group/AVQQNCA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A3A7", "url": "https://www.orthodb.org/?gene=A0A8V1A3A7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A8I0", "url": "https://www.orthodb.org/?gene=A0A8V1A8I0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46540", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46540", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46540:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46540:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07719", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07719", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015153780", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015153780", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1A3A7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3A7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A3A7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3A7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A8I0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8I0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A8I0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8I0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MATPQTLRNLRPPAMAALPDPQQEADFQRFLRRVDDISRLVQGLSSADSAVRDAAIAETDRRLRERQGSEQSAAAADRTVINTRDPVRGSVNAEAVHTEGFLAALEKDAKERAKRRKRNERLANALKEKGNDAFRKGDYSTAAQRYTDGLQKLKDMPELYTNRAQAYLKMHEYGKAIDDCKWALKCNAKCIKAYFLMGKAHLALKHYDESRQCYQNLLQIDPQKESLFKDCMNEVNLEEKRMQEEDRAMKAFQSGKHAALSIKDLLQKLDRPDQNILYYIGGIQVLTGAVKECTEQTLFRTNNGFSIINDNEVIRRGFCAERKSTAEVDLCVSLLSLWQAVCAGNEENQRLLLTHPDVNAQLSELLCSGGVEIQKETLALIALYSDNENGRRLLVRHQDLSRWLQILVMFVNSTDARASSAMSILSDLIQEEKFKAQCRLTFSTSALPLFTQLLASAKLVDQAALAHCIGIMGNLCADAAIRVQMAECNECWQACLQLVDGCGDVGTPKYRECVFAVLGLMMNLLLESNSVIQCLAVDISGRCMSLLRDQDGRIVTRAIGVLSRILAASSLAVEEAVKGGVVKKMIKFLKAGGQTTSSYALKTLSICTRGSRQAQEEVVKSDKKFSVLLKLLDSENEMIVGNAAFCLGQCLVVPGAATSLLNSNIVMALLKHAGGDAARTSVQENAAIALGKLCVAEPRHIFQLRELNGMAILNSSMKYVHSS", "length": 723, "header": "tr|A0A8V1A8I0-1|A0A8V1A8I0_CHICK Isoform 1 of Tetratricopeptide repeat domain 12 OS=Gallus gallus OX=9031 GN=TTC12 PE=4 SV=1 CANONICAL=A0A8V1A8I0-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A3A7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8I0/entry#A0A8V1A3A7-1", "sequence": { "sequence": "MAALPDPQQEADFQRFLRRVDDISRLVQGLSSADSAVRDAAIAETDRRLRERQGSEQSAAAADRTVINTRDPVRGSVNAEAVHTEGFLAALEKDAKERAKRRKRNERLANALKEKGNDAFRKGDYSTAAQRYTDGLQKLKDMPELYTNRAQAYLKMHEYGKAIDDCKWALKSRQCYQNLLQIDPQKESLFKDCMNEVNLEEKRMQEEDRAMKAFQSGKHAALSIKDLLQKLDRPDQNILYYIGGIQVLTGAVKECTEQTLFRTNNGFSIINDNEVIRRGFCAERKSTAEVDLCVSLLSLWQAVCAGNEENQRLLLTHPDVNAQLSELLCSGGVEIQKETLALIALYSDNENGRRLLVRHQDLSRWLQILVMFVNSTDARASSAMSILSDLIQEEKFKAQCRLTFSTSALPLFTQLLASAKLVDQAALAHCIGIMGNLCADAAIRVQMAECNECWQACLQLVDGCGDVGTPKYRECVFAVLGLMMNLLLESNSVIQCLAVDISGRCMSLLRDQDGRIVTRAIGVLSRILAASSLAVEEAVKGGVVKKMIKFLKAGGQTTSSYALKTLSICTRGSRQAQEEVVKSDKKFSVLLKLLDSENEMIVGNAAFCLGQCLVVPGAATSLLNSNIVMALLKHAGGDAARTSVQENAAIALGKLCVAEPRHIFQLRELNGMAILNSSMKYVHSS", "length": 685, "header": "tr|A0A8V1A3A7-1|A0A8V1A8I0_CHICK Computationally mapped isoform of Tetratricopeptide repeat domain 12 OS=Gallus gallus OX=9031 GN=TTC12 PE=4 SV=1 CANONICAL=A0A8V1A8I0-1" }, "locus": { "chromosome": "24", "start_pos": 5835518, "end_pos": 5821855, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010060915.1", "url": "https://www.ensembl.org/id/ENSGALT00010060915.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010037672.1", "url": "https://www.ensembl.org/id/ENSGALP00010037672.1" } ] } }, { "isoform_ac": "A0A8V1A8I0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8I0/entry#A0A8V1A8I0-1", "sequence": { "sequence": "MATPQTLRNLRPPAMAALPDPQQEADFQRFLRRVDDISRLVQGLSSADSAVRDAAIAETDRRLRERQGSEQSAAAADRTVINTRDPVRGSVNAEAVHTEGFLAALEKDAKERAKRRKRNERLANALKEKGNDAFRKGDYSTAAQRYTDGLQKLKDMPELYTNRAQAYLKMHEYGKAIDDCKWALKCNAKCIKAYFLMGKAHLALKHYDESRQCYQNLLQIDPQKESLFKDCMNEVNLEEKRMQEEDRAMKAFQSGKHAALSIKDLLQKLDRPDQNILYYIGGIQVLTGAVKECTEQTLFRTNNGFSIINDNEVIRRGFCAERKSTAEVDLCVSLLSLWQAVCAGNEENQRLLLTHPDVNAQLSELLCSGGVEIQKETLALIALYSDNENGRRLLVRHQDLSRWLQILVMFVNSTDARASSAMSILSDLIQEEKFKAQCRLTFSTSALPLFTQLLASAKLVDQAALAHCIGIMGNLCADAAIRVQMAECNECWQACLQLVDGCGDVGTPKYRECVFAVLGLMMNLLLESNSVIQCLAVDISGRCMSLLRDQDGRIVTRAIGVLSRILAASSLAVEEAVKGGVVKKMIKFLKAGGQTTSSYALKTLSICTRGSRQAQEEVVKSDKKFSVLLKLLDSENEMIVGNAAFCLGQCLVVPGAATSLLNSNIVMALLKHAGGDAARTSVQENAAIALGKLCVAEPRHIFQLRELNGMAILNSSMKYVHSS", "length": 723, "header": "tr|A0A8V1A8I0-1|A0A8V1A8I0_CHICK Isoform 1 of Tetratricopeptide repeat domain 12 OS=Gallus gallus OX=9031 GN=TTC12 PE=4 SV=1 CANONICAL=A0A8V1A8I0-1" }, "locus": { "chromosome": "24", "start_pos": 5835560, "end_pos": 5821855, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010060912.1", "url": "https://www.ensembl.org/id/ENSGALT00010060912.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010037669.1", "url": "https://www.ensembl.org/id/ENSGALP00010037669.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:770784", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:770784", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6GMH4-1", "protein_name": "Tetratricopeptide repeat protein 12", "gene_name": "Ttc12", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAKVGKNYTPPPALRFVSAMADDQERDLQRFLENVDEITNLIQEMNSDDPFIQQKAVLDTEKKLLLMEREQEEDGCRTTLNKTMISPPQAPENANEMNPDAFLASVEKDAKERAKRRRENRVLADALKEKGNEAFVKGDYETAIFFYSEGLGKLKDMKVLYTNRAQAYIKLGDYQKALVDCDWALKCDENCTKAYFHMGKAHLALKNYSKSKECYQKIGEINPKLKAQVKEHLNQVTLREKADLQEKKARESLDSGKNTAMTTRNLLETLSKPGQTPLFYAGGIEILTEMMTDCTERTLFRTYGGFSIINDHEVIKRCLFLAGKDAVEEIVCVSVLKLWQEVCIDNEENQRLLLSHPDMAKLLPSFMDSRILVIQQQSLALLLQLTQTDNGRNQVIKHLDMTRLCEALLSFLDFSDKKANTAIGLFTDLALEERFQVWFHANLPDVLPALTGALKREPKLTSPSALCQCIALMGNISAEPTARRHMLAYEEFGDACLDLLVKCEEDMDLYREVTYTLLGLIMNLCLEVPFLSESWAMKISRKCLSLLNSQDGGILTRAAGVLSRTLSSSQTIVEEALTAGVVKKMIKFLKTGGPTASRYAMKTLAVCTNSYHAAREEVMRLDKKFNVLMTLLASEDEVVVGNAALCLGNCMEVPSAASSLLKTDIMRVLLKLAGGDSQETAVQLNAGIALGKLCTAEPRFAVQLQELHGIQILNSTMKHLNDS", "length": 723 }, "evidence": [ { "id": "A0A8V1A8I0", "url": "https://omabrowser.org/oma/group/A0A8V1A8I0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8M3B119-1", "protein_name": "Tetratricopeptide repeat protein 12 isoform X1", "gene_name": "ttc12", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNSVSTMSLLDSDLEKFLRDVDQINELVRDLNSSEASCQENAIVKTEQLISSLEQKEQFKTKINKTVINTSSSENNPLNIRYESSQNPENFLKILEKDAEDRCQRRKMKEERANVLREQGNEAFTQGDYETAVRFYTEGLEQLRDMQALYTNRAQAFIKLKRYKEAISDCEWALRCNEKCIKAFIHMGTSHLALKDFTQSRICYRKILEIEPQRETMVKAYLRRVDMEEKVTLQEKAAWEELQEGTGQATNIADLLKKLERPNEINLYYCGGLELLSKAIKDCSGQTLFRLNNGFSIINGNITVRSCLSQNSKDPNAVDLCRSLIKLWRVVCSGNEQNQQLLMECSSARQHMVQLLASPFHEIHTESLQLLSMFAQTQHGRELIIHNLDSQQMAENLMICVCRNTSSLSPLTLLENLASEKKFQIQSRENFTAIFALPLEDLLSNTTTADPKLLASVISVIGTIAQDDAISKNLAGRKEFWRCSLQAMEQCMGCECGNVLYPLLGLMINLASNPSQVVQELAVPASSRCLGLLSHSSGGVITRAAGLLSVLLLLSSDATREAVQNGVVKKLLKMLKAGGEMSSRYSIKALTVCTASIPKAREELVKLDKRLHTLRNLLAVIDELVVGNAALCMGHCLEVDGAASCLLGTDCVALLLRHAAGDAKRAAVQQNAAITLGKLCKIEPRHMEKLRELHGLEILHSCMRLIT", "length": 707 }, "evidence": [ { "id": "A0A8V1A8I0", "url": "https://omabrowser.org/oma/group/A0A8V1A8I0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8BW49-1", "protein_name": "Tetratricopeptide repeat protein 12", "gene_name": "Ttc12", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADDQERDLQRFLENVDEITSLIQEMNSDDPFIQQKAVLDSEKKLLLMEREQEEDGCRTTLNKTMISPPQTPENADEMSPDAFLASVEKDAKERAKRRRENRVLADALKEKGNEAFVRGDYETAIFFYSEGLGKLKDMKVLYTNRAQAFIKLGDYQKALVDCDWALKCDENCTKAYFHMGKAHVALKNYSKAKECYQKIEEINPKLKAQVKEHLNQVTLREKADLQEKEAQESLDSGKNTAVTTKNLLETLSKPGQTPLFYAGGIEILTEMMADCTERTLFRTYGGFSTISDHEVIRRCLFLTGKDAVEEVLCVSVLKLWQEVCVDNEENQRLLVTHPDMARLLPSFMTSRILVIQQQSLDLLLQLTQTENGRNQVIKHLDMTQLCEALLSFLAFSDKKANTAIGILTDLALEERFQVWFQTNLPDVLPALTGALNREPKITSPSALCQCIALLGNISAEPTARKHMIAHEEFGNACLDLLVKCEEDMDLFREITYTLLGLIMNLCLEITFLSEMWVVKMSRKCLSLLNSKDGGILTRAAGVLSRTLSSSQTIVEEALTAGVVKKMIKFLRMGGQTASRYAIKILAICTNSCHAAREEVVRLDKKFDLLMLLLASEDEILAGNAALCLGNCMEVPSAAPSLLKTDIVRVLLKLAGSDSKETGVQLNAGIALGKLCTAEPRFAAQLRELHGIQVLNSTMKHLNDS", "length": 704 }, "evidence": [ { "id": "A0A8V1A8I0", "url": "https://omabrowser.org/oma/group/A0A8V1A8I0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9H892-1", "protein_name": "Tetratricopeptide repeat protein 12", "gene_name": "TTC12", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDADKEKDLQKFLKNVDEISNLIQEMNSDDPVVQQKAVLETEKRLLLMEEDQEEDECRTTLNKTMISPPQTAMKSAEEINSEAFLASVEKDAKERAKRRRENKVLADALKEKGNEAFAEGNYETAILRYSEGLEKLKDMKVLYTNRAQAYMKLEDYEKALVDCEWALKCDEKCTKAYFHMGKANLALKNYSVSRECYKKILEINPKLQTQVKGYLNQVDLQEKADLQEKEAHELLDSGKNTAVTTKNLLETLSKPDQIPLFYAGGIEILTEMINECTEQTLFRMHNGFSIISDNEVIRRCFSTAGNDAVEEMVCVSVLKLWQAVCSRNEENQRVLVIHHDRARLLAALLSSKVLAIRQQSFALLLHLAQTESGRSLIINHLDLTRLLEALVSFLDFSDKEANTAMGLFTDLALEERFQVWFQANLPGVLPALTGVLKTDPKVSSSSALCQCIAIMGNLSAEPTTRRHMAACEEFGDGCLSLLARCEEDVDLFREVIYTLLGLMMNLCLQAPFVSEVWAVEVSRRCLSLLNSQDGGILTRAAGVLSRTLSSSLKIVEEALRAGVVKKMMKFLKTGGETASRYAIKILAICTNSYHEAREEVIRLDKKLSVMMKLLSSEDEVLVGNAALCLGNCMEVPNVASSLLKTDLLQVLLKLAGSDTQKTAVQVNAGIALGKLCTAEPRFAAQLRKLHGLEILNSTMKYISDS", "length": 705 }, "evidence": [ { "id": "A0A8V1A8I0", "url": "https://omabrowser.org/oma/group/A0A8V1A8I0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A8I0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8I0" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A8I0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8I0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "sperm axoneme assembly", "id": "GO:0007288", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007288", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A8I0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8I0" } ], "pmid": "" }, { "name": "axonemal dynein complex assembly", "id": "GO:0070286", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070286", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A8I0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8I0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 412, "end_pos": 414, "annotation": "n_glycosylation_sequon" }, { "start_pos": 714, "end_pos": 716, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 412, "end_pos": 414 }, { "start_pos": 714, "end_pos": 716 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A8Q6-1", "uniprot_ac": "A0A8V1A8Q6", "uniprot_id": "A0A8V1A8Q6_CHICK", "mass": { "chemical_mass": 120319.0, "monoisotopic_mass": 120319.0 }, "refseq": {}, "gene_names": [ { "name": "NCAM1", "type": "recommended", "evidence": [ { "id": "A0A8V1A8Q6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8Q6" } ] } ], "protein_names": [ { "name": "Neural cell adhesion molecule 1", "type": "recommended", "evidence": [ { "id": "A0A8V1A8Q6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8Q6/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "This protein is a cell adhesion molecule involved in neuron-neuron adhesion, neurite fasciculation, outgrowth of neurites, etc.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A5M3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5M3#function" }, { "database": "UniProtKB", "id": "ARBA00003000", "url": "https://www.uniprot.org/uniprotkb/ARBA00003000#function" }, { "database": "UniProtKB", "id": "A0A8V1A5M8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5M8#function" }, { "database": "UniProtKB", "id": "A0A8V1A5N4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5N4#function" }, { "database": "UniProtKB", "id": "A0A8V1A3I2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3I2#function" }, { "database": "UniProtKB", "id": "A0A8V1A8Q6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8Q6#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A8Q6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8Q6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NCAM1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8Q6", "locus": { "chromosome": "24", "start_pos": 5838003, "end_pos": 5918871, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010024950", "url": "https://www.ensembl.org/id/ENSGALG00010024950" } ] } } ], "crossref": [ { "id": "A0A8V1A8Q6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A8Q6", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00063", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00063", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd00096", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00096", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd05730", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05730", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd05865", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05865", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd05869", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05869", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR003598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009138", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009138", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013098", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013098", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051170", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051170", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A3I2", "url": "https://www.orthodb.org/?gene=A0A8V1A3I2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A5M3", "url": "https://www.orthodb.org/?gene=A0A8V1A5M3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A5M8", "url": "https://www.orthodb.org/?gene=A0A8V1A5M8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A5N4", "url": "https://www.orthodb.org/?gene=A0A8V1A5N4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A8Q6", "url": "https://www.orthodb.org/?gene=A0A8V1A8Q6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12231", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12231", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12231:SF239", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12231:SF239", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00041", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00041", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07679", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07679", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13927", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13927", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1A3I2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3I2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A3I2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3I2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A5M3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5M3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A5M3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5M3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A5M8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5M8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A5M8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5M8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A5N4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5N4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A5N4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5N4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A8Q6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8Q6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A8Q6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8Q6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLPAAALPWTLFFLGAAASLQVDIVPSQGEISVGESKFFLCQVAGEAKYKDISWFSPNGEKLTPNQQRISVVRNDDFSSTLTIYNANIDDAGIYKCVVSSVEEGDSEATVNVKIFQKLMFKNAPTPQEFKEGDDAVIVCDVVSSLPPTIIWKHKGRDVILKKDVRFIVLSNNYLQIQGIKKTDEGTYRCEGRILARGEINFKDIQVIVNVPPSVRARQSTMNATANLSQSVTLACDADGFPEPTMTWTKDGEPIEQEDNEEKYSFNYDGSELIIKKVDKSDEAEYICIAENKAGEQDATIHLKVFAKPKITYVENKTAMELEDQITLTCEASGDPIPSITWKTSTRNISNEEKASWTRPEKQETLDGRIVVRSHARVSSLTLKEIQYTDAGEYVCTASNTIGQDSQAMYLEVQYAPKLQGPVAVYTWEGNQVNITCEVFAYPSAVISWFRDGQLLPSSNYSNIKIYNTPSASYLEVTPDSENDFGNYNCTAVNRIGQESSEFILVQADTPSSPSIDRVEPYSSTARVEFDEPEATGGVPILKYKAEWRALGEGEWHSRLYDAKEANVEGTITISGLKPETTYSVRLSAVNGKGVGEISLPSDFKTQPVREPSAPKLEGQMGEDGNSIKVNVIKQDDGGSPIRHYLIKYKAKHSSEWKPEIRLPSGSDHVMLKSLDWNAEYEVYVIAENQQGKSKPAHYAFRTSAQPTVIPASTSPTSGLGTAAIVGILIVIFVLLLVAVDVTCYFLNKCGLLMCIAVNLCGKSGPGAKGKDMEEGKAAFSKDESKEPIVEVRTEEERTPNHDGGKHTEPNETTPLTEPEHTADTAATVEDMLPSVTTGTTNSDTITETFATAQNSPTSETTTLTSSIAPPATAIPDSNAMSPGQATPAKAGASPVSPPPPSSTPKVAPLVDLSDTPSSAPATNNLSSSVLSNQGAVLSPSTVANMAETSKAAAGNKSAAPTPANLTSPPAPSEPKQEVSSTKSPEKEAAQPSTVKSPTETAKNPSNPKSEAASGGTTNPSQNEDFKMDEGTFKTPDIDLAKDVFAALGTTTPASVASGQARELASSTADSSVPAAPAKTEKTPVEDKSEVQATETKTPPAEVKTVPNEATQTNENESKA", "length": 1119, "header": "tr|A0A8V1A8Q6-1|A0A8V1A8Q6_CHICK Isoform 1 of Neural cell adhesion molecule 1 OS=Gallus gallus OX=9031 GN=NCAM1 PE=1 SV=1 CANONICAL=A0A8V1A8Q6-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A3I2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8Q6/entry#A0A8V1A3I2-1", "sequence": { "sequence": "MLPAAALPWTLFFLGAAASLQVDIVPSQGEISVGESKFFLCQVAGEAKYKDISWFSPNGEKLTPNQQRISVVRNDDFSSTLTIYNANIDDAGIYKCVVSSVEEGDSEATVNVKIFQKLMFKNAPTPQEFKEGDDAVIVCDVVSSLPPTIIWKHKGRDVILKKDVRFIVLSNNYLQIQGIKKTDEGTYRCEGRILARGEINFKDIQVIVNVPPSVRARQSTMNATANLSQSVTLACDADGFPEPTMTWTKDGEPIEQEDNEEKYSFNYDGSELIIKKVDKSDEAEYICIAENKAGEQDATIHLKVFAKPKITYVENKTAMELEDQITLTCEASGDPIPSITWKTSTRNISNEEKTLDGRIVVRSHARVSSLTLKEIQYTDAGEYVCTASNTIGQDSQAMYLEVQYAPKLQGPVAVYTWEGNQVNITCEVFAYPSAVISWFRDGQLLPSSNYSNIKIYNTPSASYLEVTPDSENDFGNYNCTAVNRIGQESSEFILVQADTPSSPSIDRVEPYSSTARVEFDEPEATGGVPILKYKAEWRALGEGEWHSRLYDAKEANVEGTITISGLKPETTYSVRLSAVNGKGVGEISLPSDFKTQPVQGEPSAPKLEGQMGEDGNSIKVNVIKQDDGGSPIRHYLIKYKAKHSSEWKPEIRLPSGSDHVMLKSLDWNAEYEVYVIAENQQGKSKPAHYAFRTSAQPTVIPASTSPTSGLGTAAIVGILIVIFVLLLVAVDVTCYFLNKCGLLMCIAVNLCGKSGPGAKGKDMEEGKAAFSKDESKEPIVEVRTEEERTPNHDGGKHTEPNETTPLTEPEHTADTAATVEDMLPSVTTGTTNSDTITETFATAQNSPTSETTTLTSSIAPPATAIPDSNAMSPGQATPAKAGASPVSPPPPSSTPKVAPLVDLSDTPSSAPATNNLSSSVLSNQGAVLSPSTVANMAETSKAAAGNKSAAPTPANLTSPPAPSEPKQEVSSTKSPEKEAAQPSTVKSPTETAKNPSNPKSEAASGGTTNPSQNEDFKMDEGTFKTPDIDLAKDVFAALGTTTPASVASGQARELASSTADSSVPAAPAKTEKTPVEDKSEVQATETKTPPAEVKTVPNEATQTNENESKA", "length": 1110, "header": "tr|A0A8V1A3I2-1|A0A8V1A8Q6_CHICK Computationally mapped isoform of Neural cell adhesion molecule 1 OS=Gallus gallus OX=9031 GN=NCAM1 PE=1 SV=1 CANONICAL=A0A8V1A8Q6-1" }, "locus": { "chromosome": "24", "start_pos": 5918674, "end_pos": 5841429, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010061014.1", "url": "https://www.ensembl.org/id/ENSGALT00010061014.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010037755.1", "url": "https://www.ensembl.org/id/ENSGALP00010037755.1" } ] } }, { "isoform_ac": "A0A8V1A5M3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8Q6/entry#A0A8V1A5M3-1", "sequence": { "sequence": "AASLQVDIVPSQGEISVGESKFFLCQVAGEAKYKDISWFSPNGEKLTPNQQRISVVRNDDFSSTLTIYNANIDDAGIYKCVVSSVEEGDSEATVNVKIFQKLMFKNAPTPQEFKEGDDAVIVCDVVSSLPPTIIWKHKGRDVILKKDVRFIVLSNNYLQIQGIKKTDEGTYRCEGRILARGEINFKDIQVIVNVPPSVRARQSTMNATANLSQSVTLACDADGFPEPTMTWTKDGEPIEQEDNEEKYSFNYDGSELIIKKVDKSDEAEYICIAENKAGEQDATIHLKVFAKPKITYVENKTAMELEDQITLTCEASGDPIPSITWKTSTRNISNEEKTLDGRIVVRSHARVSSLTLKEIQYTDAGEYVCTASNTIGQDSQAMYLEVQYAPKLQGPVAVYTWEGNQVNITCEVFAYPSAVISWFRDGQLLPSSNYSNIKIYNTPSASYLEVTPDSENDFGNYNCTAVNRIGQESSEFILVQADTPSSPSIDRVEPYSSTARVEFDEPEATGGVPILKYKAEWRALGEGEWHSRLYDAKEANVEGTITISGLKPETTYSVRLSAVNGKGVGEISLPSDFKTQPVREPSAPKLEGQMGEDGNSIKVNVIKQDDGGSPIRHYLIKYKAKHSSEWKPEIRLPSGSDHVMLKSLDWNAEYEVYVIAENQQGKSKPAHYAFRTSAQPTVIPATLGSPSTSSSFVSLLLSAVTLLLLC", "length": 710, "header": "tr|A0A8V1A5M3-1|A0A8V1A8Q6_CHICK Computationally mapped isoform of Neural cell adhesion molecule 1 OS=Gallus gallus OX=9031 GN=NCAM1 PE=1 SV=1 CANONICAL=A0A8V1A8Q6-1" }, "locus": { "chromosome": "24", "start_pos": 5882555, "end_pos": 5852608, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010060997.1", "url": "https://www.ensembl.org/id/ENSGALT00010060997.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010037738.1", "url": "https://www.ensembl.org/id/ENSGALP00010037738.1" } ] } }, { "isoform_ac": "A0A8V1A5M8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8Q6/entry#A0A8V1A5M8-1", "sequence": { "sequence": "AASLQVDIVPSQGEISVGESKFFLCQVAGEAKYKDISWFSPNGEKLTPNQQRISVVRNDDFSSTLTIYNANIDDAGIYKCVVSSVEEGDSEATVNVKIFQKLMFKNAPTPQEFKEGDDAVIVCDVVSSLPPTIIWKHKGRDVILKKDVRFIVLSNNYLQIQGIKKTDEGTYRCEGRILARGEINFKDIQVIVNVPPSVRARQSTMNATANLSQSVTLACDADGFPEPTMTWTKDGEPIEQEDNEEKYSFNYDGSELIIKKVDKSDEAEYICIAENKAGEQDATIHLKVFAKPKITYVENKTAMELEDQITLTCEASGDPIPSITWKTSTRNISNEEKTLDGRIVVRSHARVSSLTLKEIQYTDAGEYVCTASNTIGQDSQAMYLEVQYAPKLQGPVAVYTWEGNQVNITCEVFAYPSAVISWFRDGQLLPSSNYSNIKIYNTPSASYLEVTPDSENDFGNYNCTAVNRIGQESSEFILVQADTPSSPSIDRVEPYSSTARVEFDEPEATGGVPILKYKAEWRALGEGEWHSRLYDAKEANVEGTITISGLKPETTYSVRLSAVNGKGVGEISLPSDFKTQPVREPSAPKLEGQMGEDGNSIKVNVIKQDDGGSPIRHYLIKYKAKHSSEWKPEIRLPSGSDHVMLKSLDWNAEYEVYVIAENQQGKSKPAHYAFRTSAQPTVIPASTSPTSGLGTAAIVGILIVIFVLLLVAVDVTCYFLNKCGLLMCIAVNLCGKSGPGAKGKDMEEGKAAFSHTADTAATVEDMLPSVTTGTTNSDTITETFATAQNSPTSETTTLTSSIAPPATAIPDSNAMSPGQATPAKAGASPVSPPPPSSTPKVAPLVDLSDTPSSAPATNNLSSSVLSNQGAVLSPSTVANMAETSKAAAGNKSAAPTPANLTSPPAPSEPKQEVSSTKSPEKEAAQPSTVKSPTETAKNPSNPKSEAASGGTTNPSQNEDFKMDEGTFKTPDIDLAKDVFAALGTTTPASVASGQARELASSTADSSVPAAPAKTE", "length": 1015, "header": "tr|A0A8V1A5M8-1|A0A8V1A8Q6_CHICK Computationally mapped isoform of Neural cell adhesion molecule 1 OS=Gallus gallus OX=9031 GN=NCAM1 PE=1 SV=1 CANONICAL=A0A8V1A8Q6-1" }, "locus": { "chromosome": "24", "start_pos": 5882555, "end_pos": 5843885, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010061002.1", "url": "https://www.ensembl.org/id/ENSGALT00010061002.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010037743.1", "url": "https://www.ensembl.org/id/ENSGALP00010037743.1" } ] } }, { "isoform_ac": "A0A8V1A5N4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8Q6/entry#A0A8V1A5N4-1", "sequence": { "sequence": "AVPSLCCCLTVFCVLLSFAASLQVDIVPSQGEISVGESKFFLCQVAGEAKYKDISWFSPNGEKLTPNQQRISVVRNDDFSSTLTIYNANIDDAGIYKCVVSSVEEGDSEATVNVKIFQKLMFKNAPTPQEFKEGDDAVIVCDVVSSLPPTIIWKHKGRDVILKKDVRFIVLSNNYLQIQGIKKTDEGTYRCEGRILARGEINFKDIQVIVNVPPSVRARQSTMNATANLSQSVTLACDADGFPEPTMTWTKDGEPIEQEDNEEKYSFNYDGSELIIKKVDKSDEAEYICIAENKAGEQDATIHLKVFAKPKITYVENKTAMELEDQITLTCEASGDPIPSITWKTSTRNISNEEKTLDGRIVVRSHARVSSLTLKEIQYTDAGEYVCTASNTIGQDSQAMYLEVQYAPKLQGPVAVYTWEGNQVNITCEVFAYPSAVISWFRDGQLLPSSNYSNIKIYNTPSASYLEVTPDSENDFGNYNCTAVNRIGQESSEFILVQADTPSSPSIDRVEPYSSTARVEFDEPEATGGVPILKYKAEWRALGEGEWHSRLYDAKEANVEGTITISGLKPETTYSVRLSAVNGKGVGEISLPSDFKTQPVREPSAPKLEGQMGEDGNSIKVNVIKQDDGGSPIRHYLIKYKAKHSSEWKPEIRLPSGSDHVMLKSLDWNAEYEVYVIAENQQGKSKPAHYAFRTSAQPTVIPASTSPTSGLGTAAIVGILIVIFVLLLVAVDVTCYFLNKCGLLMCIAVNLCGKSGPGAKGKDMEEGKAAFSKDESKEPIVEVRTEEERTPNHDGGKHTEPNETTPLTEPEHTADTAATVEDMLPSVTTGTTNSDTITETFATAQNSPTSETTTLTSSIAPPATAIPDSNAMSPGQATPAKAGASPVSPPPPSSTPKVAPLVDLSDTPSSAPATNNLSSSVLSNQGAVLSPSTVANMAETSKAAAGNKSAAPTPANLTSPPAPSEPKQEVSSTKSPEKEAAQPSTVKSPTETAKNPSNPKSEAASGGTTNPSQNEDFKMDEGTFKTPDIDLAKDVFAALGTTTPASVASGQARELASSTADSSVPAAPAKTEYGCL", "length": 1076, "header": "tr|A0A8V1A5N4-1|A0A8V1A8Q6_CHICK Computationally mapped isoform of Neural cell adhesion molecule 1 OS=Gallus gallus OX=9031 GN=NCAM1 PE=1 SV=1 CANONICAL=A0A8V1A8Q6-1" }, "locus": { "chromosome": "24", "start_pos": 5882830, "end_pos": 5843873, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010061008.1", "url": "https://www.ensembl.org/id/ENSGALT00010061008.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010037748.1", "url": "https://www.ensembl.org/id/ENSGALP00010037748.1" } ] } }, { "isoform_ac": "A0A8V1A8Q6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8Q6/entry#A0A8V1A8Q6-1", "sequence": { "sequence": "MLPAAALPWTLFFLGAAASLQVDIVPSQGEISVGESKFFLCQVAGEAKYKDISWFSPNGEKLTPNQQRISVVRNDDFSSTLTIYNANIDDAGIYKCVVSSVEEGDSEATVNVKIFQKLMFKNAPTPQEFKEGDDAVIVCDVVSSLPPTIIWKHKGRDVILKKDVRFIVLSNNYLQIQGIKKTDEGTYRCEGRILARGEINFKDIQVIVNVPPSVRARQSTMNATANLSQSVTLACDADGFPEPTMTWTKDGEPIEQEDNEEKYSFNYDGSELIIKKVDKSDEAEYICIAENKAGEQDATIHLKVFAKPKITYVENKTAMELEDQITLTCEASGDPIPSITWKTSTRNISNEEKASWTRPEKQETLDGRIVVRSHARVSSLTLKEIQYTDAGEYVCTASNTIGQDSQAMYLEVQYAPKLQGPVAVYTWEGNQVNITCEVFAYPSAVISWFRDGQLLPSSNYSNIKIYNTPSASYLEVTPDSENDFGNYNCTAVNRIGQESSEFILVQADTPSSPSIDRVEPYSSTARVEFDEPEATGGVPILKYKAEWRALGEGEWHSRLYDAKEANVEGTITISGLKPETTYSVRLSAVNGKGVGEISLPSDFKTQPVREPSAPKLEGQMGEDGNSIKVNVIKQDDGGSPIRHYLIKYKAKHSSEWKPEIRLPSGSDHVMLKSLDWNAEYEVYVIAENQQGKSKPAHYAFRTSAQPTVIPASTSPTSGLGTAAIVGILIVIFVLLLVAVDVTCYFLNKCGLLMCIAVNLCGKSGPGAKGKDMEEGKAAFSKDESKEPIVEVRTEEERTPNHDGGKHTEPNETTPLTEPEHTADTAATVEDMLPSVTTGTTNSDTITETFATAQNSPTSETTTLTSSIAPPATAIPDSNAMSPGQATPAKAGASPVSPPPPSSTPKVAPLVDLSDTPSSAPATNNLSSSVLSNQGAVLSPSTVANMAETSKAAAGNKSAAPTPANLTSPPAPSEPKQEVSSTKSPEKEAAQPSTVKSPTETAKNPSNPKSEAASGGTTNPSQNEDFKMDEGTFKTPDIDLAKDVFAALGTTTPASVASGQARELASSTADSSVPAAPAKTEKTPVEDKSEVQATETKTPPAEVKTVPNEATQTNENESKA", "length": 1119, "header": "tr|A0A8V1A8Q6-1|A0A8V1A8Q6_CHICK Isoform 1 of Neural cell adhesion molecule 1 OS=Gallus gallus OX=9031 GN=NCAM1 PE=1 SV=1 CANONICAL=A0A8V1A8Q6-1" }, "locus": { "chromosome": "24", "start_pos": 5918674, "end_pos": 5841429, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010061011.1", "url": "https://www.ensembl.org/id/ENSGALT00010061011.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010037752.1", "url": "https://www.ensembl.org/id/ENSGALP00010037752.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 886, "start_aa": "Thr", "end_pos": 886, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr886", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 961, "start_aa": "Thr", "end_pos": 961, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr961", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A8Q6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8Q6" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A8Q6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8Q6" } ], "pmid": "" }, { "name": "external side of plasma membrane", "id": "GO:0009897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009897", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A8Q6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8Q6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A8Q6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8Q6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1115, "end_pos": 1117, "annotation": "n_glycosylation_sequon" }, { "start_pos": 222, "end_pos": 224, "annotation": "n_glycosylation_sequon" }, { "start_pos": 226, "end_pos": 228, "annotation": "n_glycosylation_sequon" }, { "start_pos": 315, "end_pos": 317, "annotation": "n_glycosylation_sequon" }, { "start_pos": 347, "end_pos": 349, "annotation": "n_glycosylation_sequon" }, { "start_pos": 433, "end_pos": 435, "annotation": "n_glycosylation_sequon" }, { "start_pos": 459, "end_pos": 461, "annotation": "n_glycosylation_sequon" }, { "start_pos": 488, "end_pos": 490, "annotation": "n_glycosylation_sequon" }, { "start_pos": 810, "end_pos": 812, "annotation": "n_glycosylation_sequon" }, { "start_pos": 924, "end_pos": 926, "annotation": "n_glycosylation_sequon" }, { "start_pos": 955, "end_pos": 957, "annotation": "n_glycosylation_sequon" }, { "start_pos": 964, "end_pos": 966, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1A8Q6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8Q6" }, { "id": "PS50853", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50853" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Fibronectin type-III", "eco_id": "ECO_0000259", "start_pos": 509, "end_pos": 608, "start_aa": "Thr", "end_aa": "Val", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1A8Q6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8Q6" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 8, "end_pos": 113, "start_aa": "Pro", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 886, 961 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1115, "end_pos": 1117 }, { "start_pos": 222, "end_pos": 224 }, { "start_pos": 226, "end_pos": 228 }, { "start_pos": 315, "end_pos": 317 }, { "start_pos": 347, "end_pos": 349 }, { "start_pos": 433, "end_pos": 435 }, { "start_pos": 459, "end_pos": 461 }, { "start_pos": 488, "end_pos": 490 }, { "start_pos": 810, "end_pos": 812 }, { "start_pos": 924, "end_pos": 926 }, { "start_pos": 955, "end_pos": 957 }, { "start_pos": 964, "end_pos": 966 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": 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"relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A8S0-1", "uniprot_ac": "A0A8V1A8S0", "uniprot_id": "A0A8V1A8S0_CHICK", "mass": { "chemical_mass": 126110.0, "monoisotopic_mass": 126110.0 }, "refseq": {}, "gene_names": [ { "name": "SIN3B", "type": "recommended", "evidence": [ { "id": "A0A8V1A8S0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8S0" } ] } ], "protein_names": [ { "name": "SIN3 transcription regulator family member B", "type": "synonym", "evidence": [ { "id": "A0A8V1A8S0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8S0/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A8S0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8S0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SIN3B", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8S0", "locus": { "chromosome": "28", "start_pos": 4709606, "end_pos": 4723288, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027346", "url": "https://www.ensembl.org/id/ENSGALG00010027346" } ] } } ], "crossref": [ { "id": "A0A8V1A8S0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A8S0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000003771", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000003771", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR003822", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003822", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013194", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013194", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031693", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031693", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036600", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036600", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039774", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039774", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A3V8", "url": "https://www.orthodb.org/?gene=A0A8V1A3V8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A8S0", "url": "https://www.orthodb.org/?gene=A0A8V1A8S0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NMJ8", "url": "https://www.orthodb.org/?gene=F1NMJ8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12346", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12346", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12346:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12346:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02671", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02671", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08295", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08295", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16879", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16879", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-400206", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-400206", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": 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"length": 1087, "header": "tr|A0A8V1A8S0-1|A0A8V1A8S0_CHICK Isoform 1 of SIN3 transcription regulator family member B OS=Gallus gallus OX=9031 GN=SIN3B PE=1 SV=1 CANONICAL=A0A8V1A8S0-1" }, "locus": { "chromosome": "28", "start_pos": 4722473, "end_pos": 4711995, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066306.1", "url": "https://www.ensembl.org/id/ENSGALT00010066306.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040572.1", "url": "https://www.ensembl.org/id/ENSGALP00010040572.1" } ] } }, { "isoform_ac": "F1NMJ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8S0/entry#F1NMJ8-1", "sequence": { "sequence": 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"length": 1075, "header": "tr|F1NMJ8-1|A0A8V1A8S0_CHICK Computationally mapped isoform of SIN3 transcription regulator family member B OS=Gallus gallus OX=9031 GN=SIN3B PE=1 SV=4 CANONICAL=A0A8V1A8S0-1" }, "locus": { "chromosome": "28", "start_pos": 4722720, "end_pos": 4711995, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066301.1", "url": "https://www.ensembl.org/id/ENSGALT00010066301.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040567.1", "url": "https://www.ensembl.org/id/ENSGALP00010040567.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-400206", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-400206", "resource": "Reactome", "description": "Regulation of lipid metabolism by PPARalpha" }, { "id": "R-GGA-8936459", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8936459", "resource": "Reactome", "description": "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A8S0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8S0" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A8S0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8S0" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A8S0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8S0" } ], "pmid": "" }, { "name": "Sin3-type complex", "id": "GO:0070822", "url": 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"Biological Process", "total": 1, "go_terms": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A8S0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8S0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1035, "end_pos": 1037, "annotation": "n_glycosylation_sequon" }, { "start_pos": 390, "end_pos": 392, "annotation": "n_glycosylation_sequon" }, { "start_pos": 547, "end_pos": 549, "annotation": "n_glycosylation_sequon" }, { "start_pos": 851, "end_pos": 853, "annotation": "n_glycosylation_sequon" }, { "start_pos": 97, "end_pos": 99, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1A8S0", 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{ "uniprot_canonical_ac": "A0A8V1A7A5-1", "uniprot_ac": "A0A8V1A7A5", "uniprot_id": "A0A8V1A7A5_CHICK", "mass": { "chemical_mass": 109101.0, "monoisotopic_mass": 109101.0 }, "refseq": {}, "gene_names": [ { "name": "ELAPOR1", "type": "recommended", "evidence": [ { "id": "A0A8V1A7A5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7A5" } ] } ], "protein_names": [ { "name": "Endosome-lysosome associated apoptosis and autophagy regulator 1", "type": "synonym", "evidence": [ { "id": "A0A8V1A7A5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7A5/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7A5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7A5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": 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"length": 996, "header": "tr|A0A1D5PYW4-1|A0A1D5PYW4_CHICK Computationally mapped isoform of Endosome-lysosome associated apoptosis and autophagy regulator 1 OS=Gallus gallus OX=9031 GN=ELAPOR1 PE=1 SV=2 CANONICAL=A0A8V1A7A5-1" }, "locus": { "chromosome": "26", "start_pos": 1194377, "end_pos": 1185206, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010060482.1", "url": "https://www.ensembl.org/id/ENSGALT00010060482.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010037241.1", "url": "https://www.ensembl.org/id/ENSGALP00010037241.1" } ] } }, { "isoform_ac": "A0A8V1A438-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7A5/entry#A0A8V1A438-1", "sequence": { "sequence": 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985, "header": "tr|A0A8V1A438-1|A0A8V1A7A5_CHICK Computationally mapped isoform of Endosome-lysosome associated apoptosis and autophagy regulator 1 OS=Gallus gallus OX=9031 GN=ELAPOR1 PE=1 SV=1 CANONICAL=A0A8V1A7A5-1" }, "locus": { "chromosome": "26", "start_pos": 1194377, "end_pos": 1187098, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010060475.1", "url": "https://www.ensembl.org/id/ENSGALT00010060475.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010037234.1", "url": "https://www.ensembl.org/id/ENSGALP00010037234.1" } ] } }, { "isoform_ac": "A0A8V1A7A5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7A5/entry#A0A8V1A7A5-1", "sequence": { "sequence": "MGGVVLPNPAPSSLVPKCVPQHAGCCGIGTSQKSPHIPTAAAELAGGPIPVGSQPSTRSLLQSEYHYEYTACDSAGARWRVAVPHTPGLCTGLPDPVKGTECSFSCKAGEFLDMKAQACKPCAEGTYSLGTGVRFDEWDELPHGFANVATNLELDDGFSDVVENCTTSTWVPLGDYIASNTDECTATLMYAVSLKQSGTVSFEYIYPDSSIVFEFFVQNDQCQPTVEESRWMRTTEKGWEFHSVELSRGNNVLYWRTTAFSVWSKVPKPVLVRNIGITGVAYTSECFPCKPGTFAAAAGSSSCQLCPANSFSSKGATACQPCEPTAYAEPGSASCKMRPPCTDKDYFYTHTACDANGETQLMFKWAEPKICSEALPRAAQLPPSGLKTRCPPCNPGFYKSNSSACEPCPYGSYSNGSGCVRCPAGTEPVLGLEYKWWNVLPPNMETTVLSGINFEYKGMAGWEVAGDYIYTAAGASDNDFMILTLLVPGFSPPQPALEDGDSKEVARITFVFETVCSVSCELYFMVGINSRTNTPVETWTGPRGKQSYTYVVEKNATTSFTWAFQRTRYREAGRRYTSDVAKLYSVNVTNVLGGVASFCRRCAATGGLCAPCPPGHALDHSTGACQPCPPGTFLRGHPPDGPPACQPCGPGTRSNQVRSLCYSDCTFSLALPGQTLHYDFSALSASTAFTSGPSFTSKGLKYFHHFNISLCGNHGRKAASCTDNVTDARLPDEGGSGRVVTSHVCQAIVVPSDVVGHRAAVSSQPVSLADRLLGVTVSSALDGVAAPPELFPPASPELPDVVFFFRSGEVTQSCAGGRATTIRLRCDPLRPGTGSLAVPSKCPEGTCDGCTFHLLWATAEGCPRCSANHFRAIVGACQGGVQRTTYVWKEPRLCHGGQRLPAPRVRPCRSAEFWLKVGVSVGTCVAVLLAALAAYFWKKNQKLEYKYSRLVLNAAAKESELPAPDSCAIMEGEDGEDELIFTSKKSLLGKIRCLATKRTPDGFDSVPLKPSSGGTDLEL", "length": 1019, "header": "tr|A0A8V1A7A5-1|A0A8V1A7A5_CHICK Isoform 1 of Endosome-lysosome associated apoptosis and autophagy regulator 1 OS=Gallus gallus OX=9031 GN=ELAPOR1 PE=1 SV=1 CANONICAL=A0A8V1A7A5-1" }, "locus": { "chromosome": "26", "start_pos": 1194377, "end_pos": 1187098, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010060473.1", "url": "https://www.ensembl.org/id/ENSGALT00010060473.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010037232.1", "url": "https://www.ensembl.org/id/ENSGALP00010037232.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7A5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7A5" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7A5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7A5" } ], "pmid": "" }, { "name": "lysosome", "id": "GO:0005764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005764", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7A5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7A5" } ], "pmid": "" }, { "name": "late endosome", "id": "GO:0005770", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005770", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7A5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7A5" } ], "pmid": "" }, { "name": "trans-Golgi network", "id": "GO:0005802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005802", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7A5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7A5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "autophagosome assembly", "id": "GO:0000045", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000045", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7A5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7A5" } ], "pmid": "" }, { "name": "positive regulation of vacuole organization", "id": "GO:0044090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044090", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7A5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7A5" } ], "pmid": "" }, { "name": "cellular response to starvation", "id": "GO:0009267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009267", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7A5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7A5" } ], "pmid": "" }, { "name": "positive regulation of autophagosome assembly", "id": "GO:2000786", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000786", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7A5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7A5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 164, "end_pos": 166, "annotation": "n_glycosylation_sequon" }, { "start_pos": 401, "end_pos": 403, "annotation": "n_glycosylation_sequon" }, { "start_pos": 415, "end_pos": 417, "annotation": "n_glycosylation_sequon" }, { "start_pos": 555, "end_pos": 557, "annotation": "n_glycosylation_sequon" }, { "start_pos": 587, "end_pos": 589, "annotation": "n_glycosylation_sequon" }, { "start_pos": 707, "end_pos": 709, "annotation": "n_glycosylation_sequon" }, { "start_pos": 724, "end_pos": 726, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1A7A5", "database": "UniProtKB", "url": 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{ "uniprot_canonical_ac": "A0A8V1A958-1", "uniprot_ac": "A0A8V1A958", "uniprot_id": "A0A8V1A958_CHICK", "mass": { "chemical_mass": 81827.0, "monoisotopic_mass": 81827.0 }, "refseq": { "ac": "NP_001376278", "name": "AP-4 complex subunit beta-1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376278" }, "gene_names": [ { "name": "AP4B1", "type": "recommended", "evidence": [ { "id": "A0A8V1A958", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A958" } ] }, { "name": "AP4B1", "type": "synonym", "evidence": [ { "id": "NP_001376278", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376278" } ] } ], "protein_names": [ { "name": "AP complex subunit beta", "type": "recommended", "evidence": [ { "id": "A0A8V1A958", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A958/entry#names_and_taxonomy" } ] }, { "name": "AP-4 complex subunit beta-1", "type": "synonym", "evidence": [ { "id": "NP_001376278", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376278" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR13267656.7756.1, SRR13267661.28176.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992484 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000356.1. On Sep 23, 2021 this sequence version replaced NP_001376278.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001376278", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376278" } ] }, { "annotation": "Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin-associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. It is also involved in protein sorting to the basolateral membrane in epithelial cells and the proper asymmetric localization of somatodendritic proteins in neurons. AP-4 is involved in the recognition and binding of tyrosine-based sorting signals found in the cytoplasmic part of cargos, but may also recognize other types of sorting signal.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A497", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A497#function" }, { "database": "UniProtKB", "id": "ARBA00053594", "url": "https://www.uniprot.org/uniprotkb/ARBA00053594#function" }, { "database": "UniProtKB", "id": "A0A8V1A958", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A958#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A958", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A958" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "AP4B1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A958", "locus": { "chromosome": "26", "start_pos": 3804215, "end_pos": 3811309, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027402", "url": "https://www.ensembl.org/id/ENSGALG00010027402" } ] } } ], "crossref": [ { "id": "A0A8V1A958", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A958", "database": "AlphaFoldDB", "categories": [] }, { "id": "419879", "url": "https://www.ncbi.nlm.nih.gov/gene/419879", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002553", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002553", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012295", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012295", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015151", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015151", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016342", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016342", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026739", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026739", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A492", "url": "https://www.orthodb.org/?gene=A0A8V1A492", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A497", "url": "https://www.orthodb.org/?gene=A0A8V1A497", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A958", "url": "https://www.orthodb.org/?gene=A0A8V1A958", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11134", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11134", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01602", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01602", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF09066", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09066", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-432720", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-432720", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-432722", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-432722", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001376278", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376278", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1A492", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A492", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A492-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A492-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A497", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A497", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A497-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A497-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A958", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A958", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A958-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A958-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPYLGGEEALRDLRRALSNPHVQAEPLRYRAAVLRVIRLMTQGADVSGLFAEMVKAGAAADVVQKKLVQLYVCAHAPRMPRLALLAVNTLRRDCADPSPAVRGLALRGLCDLRMPGMQEYVQQPLLSGLRDRASYVRRIAVLGCAKVHRLQGDAEVDGALVNELYSLLRDQDPIVVVNCLRALEEILKKEGGVVINKPIAHHLLNRMADLDQWGQSEVLAFLLRYRPRSEEELFNILSLLDGYLKSSSPSVVMAATKLFLVLAREYPHVQADVLVRVKGPLLAACTSESRELCFTALCHVRQILSSLPGHFSSHYKKFFCSYSEPHYIKCQKMEVLCELVNDENVQQVLEELKGYCTDISVELAQGAISAIGSIARTYTEQCVGILTELLGLQQEHITSAVVQAFRDLVWLCPQCTDAVCQALPGCEDIIQDSEGKQALIWLLGAHGEKVPNAPYVLEDFVENVKTEVFPAVKMELLTALVRLFLSRPAECQDMLGRLLYHCIEEEKDMSVRDRGLFYYRLLQSGVDEVKRVLCSPKSDPSLGLLEDQTEQPVNTWASEFNTLAPIYGKARWALVTAHQPGEPCYAFSPCTDSGNRGTGSLISEGSKEVLKVHPDTGSLTLIPDVVLTAEQFEKTWLSLDISCQQSLPWVGTVHPDTIQTALHVVHIQTIAMSKAGVQPWKAYFTAQDDSGCLFLTELLLEAEDSGMQVAVKQSEAKPEALQAFMSVFRTAVGAVAGLRS", "length": 740, "header": "tr|A0A8V1A958-1|A0A8V1A958_CHICK Isoform 1 of AP complex subunit beta OS=Gallus gallus OX=9031 GN=AP4B1 PE=3 SV=1 CANONICAL=A0A8V1A958-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A492-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A958/entry#A0A8V1A492-1", "sequence": { "sequence": "MADLDQWGQSEVLAFLLRYRPRSEEELFNILSLLDGYLKSSSPSVVMAATKLFLVLAREYPHVQADVLVRVKGPLLAACTSESRELCFTALCHVRQILSSLPGHFSSHYKKFFCSYSEPHYIKCQKMEVLCELVNDENVQQVLEELKGYCTDISVELAQGAISAIGSIARTYTEQCVGILTELLGLQQEHITSAVVQAFRDLVWLCPQCTDAVCQALPGCEDIIQDSEGKQALIWLLGAHGEKVPNAPYVLEDFVENVKTEVFPAVKMELLTALVRLFLSRPAECQDMLGRLLYHCIEEEKDMSVRDRGLFYYRLLQSGVDEVKRVLCSPKSDPSLGLLEDQTEQPVNTWASEFNTLAPIYGKARWALVTAHQPGEPCYAFSPCTDSGNRGTGSLISEGSKEVLKVHPDTGSLTLIPDVVLTAEQFEKTWLSLDISCQQSLPWVGTVHPDTIQTALHVVHIQTIAMSKAGVQPWKAYFTAQDDSGCLFLTELLLEAEDSGMQVAVKQSEAKPEALQAFMSVFRTAVGAVAGLRS", "length": 534, "header": "tr|A0A8V1A492-1|A0A8V1A958_CHICK Computationally mapped isoform of AP complex subunit beta OS=Gallus gallus OX=9031 GN=AP4B1 PE=3 SV=1 CANONICAL=A0A8V1A958-1" }, "locus": { "chromosome": "26", "start_pos": 3809444, "end_pos": 3805506, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066437.1", "url": "https://www.ensembl.org/id/ENSGALT00010066437.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040703.1", "url": "https://www.ensembl.org/id/ENSGALP00010040703.1" } ] } }, { "isoform_ac": "A0A8V1A497-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A958/entry#A0A8V1A497-1", "sequence": { "sequence": "MPGMQEYVQQPLLSGLRDRASYVRRIAVLGCAKVHRLQGDAEVDGALVNELYSLLRDQDPIVVVNCLRALEEILKKEGGVVINKPIAHHLLNRMADLDQWGQSEVLAFLLRYRPRSEEELFNILSLLDGYLKSSSPSVVMAATKLFLVLAREYPHVQADVLVRVKGPLLAACTSESRELCFTALCHVRQILSSLPGHFSSHYKKFFCSYSEPHYIKCQKMEVLCELVNDENVQQVLEELKGYCTDISVELAQGAISAIGSIARTYTEQCVGILTELLGLQQEHITSAVVQAFRDLVWLCPQCTDAVCQALPGCEDIIQDSEGKQALIWLLGAHGEKVPNAPYVLEDFVENVKTEVFPAVKMELLTALVRLFLSRPAECQDMLGRLLYHCIEEEKDMSVRDRGLFYYRLLQSGVDEVKRVLCSPKSDPSLGLLEDQTEQPVNTWASEFNTLAPIYGKARWALVTAHQPGEPCYAFSPCTDSGNRGTGSLISEGSKEVLKVHPDTGSLTLIPDVVLTAEQFEKTWLSLDISCQQSLPWVGTVHPDTIQTALHVVHIQTIAMSKAGVQPWKAYFTAQDDSGCLFLTELLLEAEDSGMQVAVKQSEAKPEALQAFMSVFRTAVGAVAGLRS", "length": 627, "header": "tr|A0A8V1A497-1|A0A8V1A958_CHICK Computationally mapped isoform of AP complex subunit beta OS=Gallus gallus OX=9031 GN=AP4B1 PE=3 SV=1 CANONICAL=A0A8V1A958-1" }, "locus": { "chromosome": "26", "start_pos": 3810649, "end_pos": 3805506, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066442.1", "url": "https://www.ensembl.org/id/ENSGALT00010066442.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040708.1", "url": "https://www.ensembl.org/id/ENSGALP00010040708.1" } ] } }, { "isoform_ac": "A0A8V1A958-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A958/entry#A0A8V1A958-1", "sequence": { "sequence": "MPYLGGEEALRDLRRALSNPHVQAEPLRYRAAVLRVIRLMTQGADVSGLFAEMVKAGAAADVVQKKLVQLYVCAHAPRMPRLALLAVNTLRRDCADPSPAVRGLALRGLCDLRMPGMQEYVQQPLLSGLRDRASYVRRIAVLGCAKVHRLQGDAEVDGALVNELYSLLRDQDPIVVVNCLRALEEILKKEGGVVINKPIAHHLLNRMADLDQWGQSEVLAFLLRYRPRSEEELFNILSLLDGYLKSSSPSVVMAATKLFLVLAREYPHVQADVLVRVKGPLLAACTSESRELCFTALCHVRQILSSLPGHFSSHYKKFFCSYSEPHYIKCQKMEVLCELVNDENVQQVLEELKGYCTDISVELAQGAISAIGSIARTYTEQCVGILTELLGLQQEHITSAVVQAFRDLVWLCPQCTDAVCQALPGCEDIIQDSEGKQALIWLLGAHGEKVPNAPYVLEDFVENVKTEVFPAVKMELLTALVRLFLSRPAECQDMLGRLLYHCIEEEKDMSVRDRGLFYYRLLQSGVDEVKRVLCSPKSDPSLGLLEDQTEQPVNTWASEFNTLAPIYGKARWALVTAHQPGEPCYAFSPCTDSGNRGTGSLISEGSKEVLKVHPDTGSLTLIPDVVLTAEQFEKTWLSLDISCQQSLPWVGTVHPDTIQTALHVVHIQTIAMSKAGVQPWKAYFTAQDDSGCLFLTELLLEAEDSGMQVAVKQSEAKPEALQAFMSVFRTAVGAVAGLRS", "length": 740, "header": "tr|A0A8V1A958-1|A0A8V1A958_CHICK Isoform 1 of AP complex subunit beta OS=Gallus gallus OX=9031 GN=AP4B1 PE=3 SV=1 CANONICAL=A0A8V1A958-1" }, "locus": { "chromosome": "26", "start_pos": 3811259, "end_pos": 3805506, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066444.1", "url": "https://www.ensembl.org/id/ENSGALT00010066444.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040710.1", "url": "https://www.ensembl.org/id/ENSGALP00010040710.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-432720", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-432720", "resource": "Reactome", "description": "Lysosome Vesicle Biogenesis" }, { "id": "R-GGA-432722", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-432722", "resource": "Reactome", "description": "Golgi Associated Vesicle Biogenesis" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A958", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A958" } ], "pmid": "" }, { "name": "vesicle-mediated transport", "id": "GO:0016192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016192", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A958", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A958" } ], "pmid": "" }, { "name": "protein targeting", "id": "GO:0006605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006605", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A958", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A958" } ], "pmid": "" }, { "name": "protein localization to somatodendritic compartment", "id": "GO:0061938", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061938", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A958", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A958" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A958", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A958" } ], "pmid": "" }, { "name": "clathrin adaptor complex", "id": "GO:0030131", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030131", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A958", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A958" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A958", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A958" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A958", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A958" } ], "pmid": "" }, { "name": "trans-Golgi network", "id": "GO:0005802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005802", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A958", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A958" } ], "pmid": "" }, { "name": "AP-4 adaptor complex", "id": "GO:0030124", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030124", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A958", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A958" } ], "pmid": "" }, { "name": "cytoplasmic side of trans-Golgi network transport vesicle membrane", "id": "GO:0098541", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098541", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A958", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A958" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "clathrin binding", "id": "GO:0030276", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030276", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A958", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A958" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1A958", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A958" }, { "id": "SM01020", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM01020" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Beta-adaptin appendage C-terminal subdomain", "eco_id": "ECO_0000259", "start_pos": 621, "end_pos": 733, "start_aa": "Leu", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A9A2-1", "uniprot_ac": "A0A8V1A9A2", "uniprot_id": "A0A8V1A9A2_CHICK", "mass": { "chemical_mass": 113581.0, "monoisotopic_mass": 113581.0 }, "refseq": { "ac": "XP_040504381", "name": "ataxin-2 isoform X21", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040504381" }, "gene_names": [ { "name": "ATXN2", "type": "recommended", "evidence": [ { "id": "A0A8V1A9A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9A2" } ] }, { "name": "ATXN2", "type": "synonym", "evidence": [ { "id": "XP_040504381", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040504381" } ] } ], "protein_names": [ { "name": "Ataxin 2", "type": "synonym", "evidence": [ { "id": "A0A8V1A9A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9A2/entry#names_and_taxonomy" } ] }, { "name": "ataxin-2 isoform X21", "type": "synonym", "evidence": [ { "id": "XP_040504381", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040504381" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052546.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040504381", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040504381" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9A2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9A2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ATXN2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9A2", "locus": { "chromosome": "15", "start_pos": 6137565, "end_pos": 6187900, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010025805", "url": "https://www.ensembl.org/id/ENSGALG00010025805" } ] } } ], "crossref": [ { "id": "A0A8V1A9A2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A9A2", "database": "AlphaFoldDB", "categories": [] }, { "id": "416877", "url": "https://www.ncbi.nlm.nih.gov/gene/416877", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR009604", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009604", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009818", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009818", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025852", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025852", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045117", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045117", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047575", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047575", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A499", "url": "https://www.orthodb.org/?gene=A0A8V1A499", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A982", "url": "https://www.orthodb.org/?gene=A0A8V1A982", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A9A2", "url": "https://www.orthodb.org/?gene=A0A8V1A9A2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ABN6", "url": "https://www.orthodb.org/?gene=A0A8V1ABN6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ABQ1", "url": "https://www.orthodb.org/?gene=A0A8V1ABQ1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12854", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12854", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12854:SF11", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12854:SF11", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06741", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06741", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07145", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07145", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14438", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14438", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040504381", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040504381", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1A499", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A499", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A499-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A499-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A982", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A982", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A982-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A982-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A9A2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9A2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A9A2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9A2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ABN6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABN6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ABN6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABN6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ABQ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABQ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ABQ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABQ1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSLKQTAAASQPAGNNRKPPGGGGSGGGGGGGGGGGLPSASGGGRQNMGRGRSSGKGPPQPTISFDGIYANMRMVHILTSVVGSKCEVQVKNGGIYEGVFKTYSPKCDLVLDAAHRKTAESSLGPKREDILESILFKSSDFVMVHFKDMDTNYARRDAFTDSAISAKVNGEHKEKDLEPWDGGETSATEELEALETDVSNGWDPNDMFRYNEENYGVISTYDSSLSSYTVPLERDNSEEFLKREARATQLAEEIESSAQYKARVALENDERTEEEKYTAVQRNANEREGHGVNTRESKYVPPGGRNRDVLSWGSGRQNSPRMGQSGSGPPISRSGSHTSDFSPNSGADQRVVNGGVPWPSPCPSPSSRPPSRYQSGPNSLPPRAATPTRPPSRPPSRPSRPPSHPSAHGSPAPVSTMPKRMSSEGPPRMSPKAQRHPRGHRVSTVPRLSPKTHRPRSPRQSSTPAGPALPSPQPGTIPTESVAMPVPAASPTPASPASNRAVTPSNEAKDTRLQDQRQNSAAGNKENIKPSETSPSFPKPESKGVSPIVSEHRKQIDDLKKFKNDFRLQSSSSSDAVDQLLNKTREGEKSRDVVKEKTEPAPKEPIIETGSNTNSNGGSSKPNSPSISPSISNSSEQKRGPEVTSQGVQTSGPGSKQDKEDKEEKKDTSEQVRKSTLNPNAKEFNPRSFAQPKPSTTPTSPRPQAQPSPSMVGHQQPTPVYTQPVCFAPNMMYPVPVSPGVQPLYPIPMTPMPVNQAKTYRAVPNMPQQRQDQHHQSTMMHPASAAGPPIVATPPAYSTQYVAYSPQQFPNQPLVQHVPHYQSQHPHVYSPVIQGNARMMAPPTHAQPGLVSSSATQYGAHEQTHAMYVSTGSLAQQYAHPNATLHPHPPHPQPSATPTGQQQSQHAGSHPAPSPVQHHQHQAAQALHLANPQQQSAIYHAGLAPTPPSMTPGSNTQSPQNSFPTAQQTVFTIHPSHVQPAYTNPPHMAHVPQAHVQSGMVPSHPTAHAPMMLMTTQPPGGPQAAIAQSALQPIPVSTTTHFPYMTHPSVQAHHQQQL", "length": 1058, "header": "tr|A0A8V1A9A2-1|A0A8V1A9A2_CHICK Isoform 1 of Ataxin 2 OS=Gallus gallus OX=9031 GN=ATXN2 PE=1 SV=1 CANONICAL=A0A8V1A9A2-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A499-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9A2/entry#A0A8V1A499-1", "sequence": { "sequence": "MSLKQTAAASQPAGNNRKPPGGGGSGGGGGGGGGGGLPSASGGGRQNMGRGRSSGKGPPQPTISFDGIYANMRMVHILTSVVGSKCEVQVKNGGIYEGVFKTYSPKCDLVLDAAHRKTAESSLGPKREDILESILFKSSDFVMVHFKDMDTNYARRDAFTDSAISAKVNGEHKEKDLEPWDGGETSATEELEALETDVSNGWDPNDMFRYNEENYGVISTYDSSLSSYTVPLERDNSEEFLKREARATQLAEEIESSAQYKARVALENDERTEEEKYTAVQRNANEREGHGVNTRESKYVPPGGRNRDVLSWGSGRQNSPRMGQSGSGPPISRSGSHTSDFSPNSGADQRVVNGGPPRMSPKAQRHPRGHRVSTGRGTISSGLEFVSHNAPGEASTTAVARGSPSGGTWSSVVSGVPRLSPKTHRPRSPRQSSTPAGPALPSPQPGTIPTESVAMPVPAASPTPASPASNRAVTPSNEAKDTRLQDQRQNSAAGNKENIKPSETSPSFPKPESKGVSPIVSEHRKQIDDLKKFKNDFRLQSSSSSDAVDQLLNKTREGEKSRDVVKEKTEPAPKEPIIETGSNTNSNGGSSKPNSPSISPSISNSSEQKRGPEVTSQGVQTSGPGSKQDKEDKEEKKDTSEQVRKSTLNPNAKEFNPRSFAQPKPSTTPTSPRPQAQPSPSMVGHQQPTPVYTQPVCFAPNMMYPVPVSPGVQPLYPIPMTPMPVNQAKTYRAVPNMPQQRQDQHHQSTMMHPASAAGPPIVATPPAYSTQYVAYSPQQFPNQPLVQHVPHYQSQHPHVYSPVIQGNARMMAPPTHAQPGLVSSSATQYGAHEQTHAMYVSTGSLAQQYAHPNATLHPHPPHPQPSATPTGQQQSQHAGSHPAPSPVQHHQHQAAQALHLANPQQQSAIYHAGLAPTPPSMTPGSNTQSPQNSFPTAQQTVFTIHPSHVQPAYTNPPHMAHVPQVNTV", "length": 968, "header": "tr|A0A8V1A499-1|A0A8V1A9A2_CHICK Computationally mapped isoform of Ataxin 2 OS=Gallus gallus OX=9031 GN=ATXN2 PE=1 SV=1 CANONICAL=A0A8V1A9A2-1" }, "locus": { "chromosome": "15", "start_pos": 6187445, "end_pos": 6142686, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010062933.1", "url": "https://www.ensembl.org/id/ENSGALT00010062933.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038869.1", "url": "https://www.ensembl.org/id/ENSGALP00010038869.1" } ] } }, { "isoform_ac": "A0A8V1A982-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9A2/entry#A0A8V1A982-1", "sequence": { "sequence": "MSLKQTAAASQPAGNNRKPPGGGGSGGGGGGGGGGGLPSASGGGRQNMGRGRSSGKGPPQPTISFDGIYANMRMVHILTSVVGSKCEVQVKNGGIYEGVFKTYSPKCDLVLDAAHRKTAESSLGPKREDILESILFKSSDFVMVHFKDMDTNYARRDAFTDSAISAKVNGEHKEKDLEPWDGGETSATEELEALETDVSNGWDPNDMFRYNEENYGVISTYDSSLSSYTVPLERDNSEEFLKREARATQLAEEIESSAQYKARVALENDERTEEEKYTAVQRNANEREGHGVNTRESKYVPPGGRNRDVLSWGSGRQNSPRMGQSGSGPPISRSGSHTSDFSPNSGADQRVVNGGPPRMSPKAQRHPRGHRVSTGRGTISSGLEFVSHNAPGEASTTAVARGSPSGGTWSSVVSGVPRLSPKTHRPRSPRQSSTPAGPALPSPQPGTIPTESVAMPVPAASPTPASPASNRAVTPSNEAKDTRLQDQRQNSAAGNKENIKPSETSPSFPKPESKGVSPIVSEHRKQIDDLKKFKNDFRLQSSSSSDAVDQLLNKTREGEKSRDVVKEKTEPAPKEPIIETGSNTNSNGGSSKPNSPSISPSISNSSEQKRGPEVTSQGVQTSGPGSKQDKEDKEEKKDTSEQVRKSTLNPNAKEFNPRSFAQPKPSTTPTSPRPQAQPSPSMVGHQQPTPVYTQPVCFAPNMMYPVPVSPGVQPLYPIPMTPMPVNQAKTYRAVPNMPQQRQDQHHQSTMMHPASAAGPPIVATPPAYSTQYVAYSPQQFPNQPLVQHVPHYQSQHPHVYSPVIQGNARMMAPPTHAQPGLVSSSATQYGAHEQTHAMYACPKIPYSKETGPSFYFAISTGSLAQQYAHPNATLHPHPPHPQPSATPTGQQQSQHAGSHPAPSPVQHHQHQAAQALHLANPQQQSAIYHAGLAPTPPSMTPGSNTQSPQNSFPTAQQTVFTIHPSHVQPAYTNPPHMAHVPQVNTV", "length": 986, "header": "tr|A0A8V1A982-1|A0A8V1A982_CHICK Computationally mapped isoform of Ataxin 2 OS=Gallus gallus OX=9031 GN=ATXN2 PE=1 SV=1 CANONICAL=A0A8V1A9A2-1" }, "locus": { "chromosome": "15", "start_pos": 6187445, "end_pos": 6142686, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010062921.1", "url": "https://www.ensembl.org/id/ENSGALT00010062921.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038860.1", "url": "https://www.ensembl.org/id/ENSGALP00010038860.1" } ] } }, { "isoform_ac": "A0A8V1A9A2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9A2/entry#A0A8V1A9A2-1", "sequence": { "sequence": "MSLKQTAAASQPAGNNRKPPGGGGSGGGGGGGGGGGLPSASGGGRQNMGRGRSSGKGPPQPTISFDGIYANMRMVHILTSVVGSKCEVQVKNGGIYEGVFKTYSPKCDLVLDAAHRKTAESSLGPKREDILESILFKSSDFVMVHFKDMDTNYARRDAFTDSAISAKVNGEHKEKDLEPWDGGETSATEELEALETDVSNGWDPNDMFRYNEENYGVISTYDSSLSSYTVPLERDNSEEFLKREARATQLAEEIESSAQYKARVALENDERTEEEKYTAVQRNANEREGHGVNTRESKYVPPGGRNRDVLSWGSGRQNSPRMGQSGSGPPISRSGSHTSDFSPNSGADQRVVNGGVPWPSPCPSPSSRPPSRYQSGPNSLPPRAATPTRPPSRPPSRPSRPPSHPSAHGSPAPVSTMPKRMSSEGPPRMSPKAQRHPRGHRVSTVPRLSPKTHRPRSPRQSSTPAGPALPSPQPGTIPTESVAMPVPAASPTPASPASNRAVTPSNEAKDTRLQDQRQNSAAGNKENIKPSETSPSFPKPESKGVSPIVSEHRKQIDDLKKFKNDFRLQSSSSSDAVDQLLNKTREGEKSRDVVKEKTEPAPKEPIIETGSNTNSNGGSSKPNSPSISPSISNSSEQKRGPEVTSQGVQTSGPGSKQDKEDKEEKKDTSEQVRKSTLNPNAKEFNPRSFAQPKPSTTPTSPRPQAQPSPSMVGHQQPTPVYTQPVCFAPNMMYPVPVSPGVQPLYPIPMTPMPVNQAKTYRAVPNMPQQRQDQHHQSTMMHPASAAGPPIVATPPAYSTQYVAYSPQQFPNQPLVQHVPHYQSQHPHVYSPVIQGNARMMAPPTHAQPGLVSSSATQYGAHEQTHAMYVSTGSLAQQYAHPNATLHPHPPHPQPSATPTGQQQSQHAGSHPAPSPVQHHQHQAAQALHLANPQQQSAIYHAGLAPTPPSMTPGSNTQSPQNSFPTAQQTVFTIHPSHVQPAYTNPPHMAHVPQAHVQSGMVPSHPTAHAPMMLMTTQPPGGPQAAIAQSALQPIPVSTTTHFPYMTHPSVQAHHQQQL", "length": 1058, "header": "tr|A0A8V1A9A2-1|A0A8V1A9A2_CHICK Isoform 1 of Ataxin 2 OS=Gallus gallus OX=9031 GN=ATXN2 PE=1 SV=1 CANONICAL=A0A8V1A9A2-1" }, "locus": { "chromosome": "15", "start_pos": 6187445, "end_pos": 6138178, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010062941.1", "url": "https://www.ensembl.org/id/ENSGALT00010062941.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038875.1", "url": "https://www.ensembl.org/id/ENSGALP00010038875.1" } ] } }, { "isoform_ac": "A0A8V1ABN6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9A2/entry#A0A8V1ABN6-1", "sequence": { "sequence": "MSLKQTAAASQPAGNNRKPPGGGGSGGGGGGGGGGGLPSASGGGRQNMGRGRSSGKGPPQPTISFDGIYANMRMVHILTSVVGSKCEVQVKNGGIYEGVFKTYSPKCDLVLDAAHRKTAESSLGPKREDILESILFKSSDFVMVHFKDMDTNYARRDAFTDSAISAKVNGEHKEKDLEPWDGGETSATEELEALETDVSNGWDPNDMFRYNEENYGVISTYDSSLSSYTVPLERDNSEEFLKREARATQLAEEIESSAQYKARVALENDERTEEEKYTAVQRNANEREGHGVNTRESKYVPPGGRNRDVLSWGSGRQNSPRMGQSGSGPPISRSGSHTSDFSPNSGADQRVVNGGPPRMSPKAQRHPRGHRVSTGRGTISSGLEFVSHNAPGEASTTAVARGSPSGGTWSSVVSGVPRLSPKTHRPRSPRQSSTPAGPALPSPQPGTIPTESVAMPVPAASPTPASPASNRAVTPSNEAKDTRLQDQRQNSAAGNKENIKPSETSPSFPKPESKGVSPIVSEHRKQIDDLKKFKNDFRLQSSSSSDAVDQLLNKTREGEKSRDVVKEKTEPAPKEPIIETGSNTNSNGGSSKPNSPSISPSISNSSEQKRGPEVTSQGVQTSGPGSKQDKEDKEEKKDTSEQVRKSTLNPNAKEFNPRSFAQPKPSTTPTSPRPQAQPSPSMVGHQQPTPVYTQPVCFAPNMMYPVPVSPGVQPLYPIPMTPMPVNQAKTYRAGKVPNMPQQRQDQHHQSTMMHPASAAGPPIVATPPAYSTQYVAYSPQQFPNQPLVQHVPHYQSQHPHVYSPVIQGNARMMAPPTHAQPGLVSSSATQYGAHEQTHAMYVSTGSLAQQYAHPNATLHPHPPHPQPSATPTGQQQSQHAGSHPAPSPVQHHQHQAAQALHLANPQQQSAIYHAGLAPTPPSMTPGSNTQSPQNSFPTAQQTVFTIHPSHVQPAYTNPPHMAHVPQVNTV", "length": 970, "header": "tr|A0A8V1ABN6-1|A0A8V1ABN6_CHICK Computationally mapped isoform of Ataxin 2 OS=Gallus gallus OX=9031 GN=ATXN2 PE=1 SV=1 CANONICAL=A0A8V1A9A2-1" }, "locus": { "chromosome": "15", "start_pos": 6187445, "end_pos": 6142686, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010062927.1", "url": "https://www.ensembl.org/id/ENSGALT00010062927.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038863.1", "url": "https://www.ensembl.org/id/ENSGALP00010038863.1" } ] } }, { "isoform_ac": "A0A8V1ABQ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9A2/entry#A0A8V1ABQ1-1", "sequence": { "sequence": "MSLKQTAAASQPAGNNRKPPGGGGSGGGGGGGGGGGLPSASGGGRQNMGRGRSSGKGPPQPTISFDGIYANMRMVHILTSVVGSKCEVQVKNGGIYEGVFKTYSPKCDLVLDAAHRKTAESSLGPKREDILESILFKSSDFVMVHFKDMDTNYARRDAFTDSAISAKVNGEHKEKDLEPWDGGETSATEELEALETDVSNGWDPNDMFRYNEENYGVISTYDSSLSSYTVPLERDNSEEFLKREARATQLAEEIESSAQYKARVALENDERTEEEKYTAVQRNANEREGHGVNTRESKYVPPGGRNRDVLSWGSGRQNSPRMGQSGSGPPISRSGSHTSDFSPNSGADQRVVNGGPPRMSPKAQRHPRGHRVSTGRGTISSGLEFVSHNAPGEASTTAVARGSPSGGTWSSVVSGVPRLSPKTHRPRSPRQSSTPAGPALPSPQPGTIPTESVAMPVPAASPTPASPASNRAVTPSNEAKDTRLQDQRQNSAAGNKENIKPSETSPSFPKPESKGVSPIVSEHRKQIDDLKKFKNDFRLQSSSSSDAVDQLLNKTREGEKSRDVVKEKTEPAPKEPIIETGSNTNSNGGSSKPNSPSISPSISNSSEQKRGPEVTSQGVQTSGPGSKQDKEDKEEKKDTSEQVRKSTLNPNAKEFNPRSFAQPKPSTTPTSPRPQAQPSPSMVGHQQPTPVYTQPVCFAPNMMYPVPVSPGVQPLYPIPMTPMPVNQAKTYRAGKVPNMPQQRQDQHHQSTMMHPASAAGPPIVATPPAYSTQYVAYSPQQFPNQPLVQHVPHYQSQHPHVYSPVIQGNARMMAPPTHAQPGLVSSSATQYGAHEQTHAMYVSTGSLAQQYAHPNATLHPHPPHPQPSATPTGQQQSQHAGSHPAPSPVQHHQHQAAQALHLANPQQQSAIYHAGLAPTPPSMTPGSNTQSPQNSFPTAQQTVFTIHPSHVQPAYTNPPHMAHVPQAHVQSGMVPSHPTAHAPMMLMTTQPPGGPQAAIAQSALQPIPVSTTTHFPYMTHPSVQAHHQQQL", "length": 1031, "header": "tr|A0A8V1ABQ1-1|A0A8V1ABQ1_CHICK Computationally mapped isoform of Ataxin 2 OS=Gallus gallus OX=9031 GN=ATXN2 PE=1 SV=1 CANONICAL=A0A8V1A9A2-1" }, "locus": { "chromosome": "15", "start_pos": 6187445, "end_pos": 6138178, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010062946.1", "url": "https://www.ensembl.org/id/ENSGALT00010062946.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038878.1", "url": "https://www.ensembl.org/id/ENSGALP00010038878.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 492, "start_aa": "Thr", "end_pos": 492, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr492", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 503, "start_aa": "Thr", "end_pos": 503, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr503", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 62, "start_aa": "Thr", "end_pos": 62, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr62", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 946, "start_aa": "Thr", "end_pos": 946, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr946", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9A2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9A2" } ], "pmid": "" }, { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9A2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9A2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasmic stress granule", "id": "GO:0010494", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010494", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9A2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9A2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "stress granule assembly", "id": "GO:0034063", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034063", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9A2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9A2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 582, "end_pos": 584, "annotation": "n_glycosylation_sequon" }, { "start_pos": 633, "end_pos": 635, "annotation": "n_glycosylation_sequon" }, { "start_pos": 882, "end_pos": 884, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1A9A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9A2" }, { "id": "PS52002", "database": "PROSITE", "url": "https://prosite.expasy.org/PS52002" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Sm", "eco_id": "ECO_0000259", "start_pos": 73, "end_pos": 150, "start_aa": "Arg", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], 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{ "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A9H7-1", "uniprot_ac": "A0A8V1A9H7", "uniprot_id": "A0A8V1A9H7_CHICK", "mass": { 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"UniProtKB", "id": "A0A8V1AEW1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEW1#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9H7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9H7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9H7", "locus": {} } ], "crossref": [ { "id": "A0A8V1A9H7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A9H7", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR000073", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000073", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029058", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029058", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR46197", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46197", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46197:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46197:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12697", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12697", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1A4K9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4K9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A4K9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4K9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A9H7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9H7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A9H7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9H7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AEW1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEW1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AEW1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEW1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "SGGAAWRARPRAGGWNRALPSPARVEPTMPRGRAALLALGALLACGLLLLPPAARRHVPARLPANATVRAGVAWVGRRPDVLLLHGQAFSSGTWQALGTLALLAAEGHRAVAIDLPGRSESAGAVARGRGRAAFLRHVVQRLGLRRPVLVSPSMSGRFALPFLLAHGRQLAGFVPIAPVGTREYGAVQYQQVQTPTLILYGDRDTGLGQQALQSLRHLPKHRVVVLPGAGHACYMDKPEDFHRALLGFLGQLQ", "length": 253, "header": "tr|A0A8V1A9H7-1|A0A8V1A9H7_CHICK Isoform 1 of Protein ABHD14A OS=Gallus gallus OX=9031 GN= PE=1 SV=1 CANONICAL=A0A8V1A9H7-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A4K9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9H7/entry#A0A8V1A4K9-1", "sequence": { "sequence": "GASPPHRRKAVRAVGGPAPCRALVSSPCPPPIPRRPDVLLLHGQAFSSGTWQALGTLALLAAEGHRAVAIDLPGRSESAGAVPARGALPLHLSPRGRAAFLRHVVQRLGLRRPVLVSPSMSGRFALPFLLAHGRQLAGFVPIAPVGTREYGAVQYQQVQTPTLILYGDRDTGLGQQALQSLRHLPKHRVVVLPGAGHACYMDKPEDFHRALLGFLGQLQ", "length": 219, "header": "tr|A0A8V1A4K9-1|A0A8V1A9H7_CHICK Computationally mapped isoform of Protein ABHD14A OS=Gallus gallus OX=9031 GN= PE=1 SV=1 CANONICAL=A0A8V1A9H7-1" }, "locus": { "chromosome": "12", "start_pos": 3317665, "end_pos": 3316268, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066696.1", "url": "https://www.ensembl.org/id/ENSGALT00010066696.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040837.1", "url": "https://www.ensembl.org/id/ENSGALP00010040837.1" } ] } }, { "isoform_ac": "A0A8V1A9H7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9H7/entry#A0A8V1A9H7-1", "sequence": { "sequence": "SGGAAWRARPRAGGWNRALPSPARVEPTMPRGRAALLALGALLACGLLLLPPAARRHVPARLPANATVRAGVAWVGRRPDVLLLHGQAFSSGTWQALGTLALLAAEGHRAVAIDLPGRSESAGAVARGRGRAAFLRHVVQRLGLRRPVLVSPSMSGRFALPFLLAHGRQLAGFVPIAPVGTREYGAVQYQQVQTPTLILYGDRDTGLGQQALQSLRHLPKHRVVVLPGAGHACYMDKPEDFHRALLGFLGQLQ", "length": 253, "header": "tr|A0A8V1A9H7-1|A0A8V1A9H7_CHICK Isoform 1 of Protein ABHD14A OS=Gallus gallus OX=9031 GN= PE=1 SV=1 CANONICAL=A0A8V1A9H7-1" }, "locus": { "chromosome": "12", "start_pos": 3317993, "end_pos": 3316268, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066698.1", "url": "https://www.ensembl.org/id/ENSGALT00010066698.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040839.1", "url": "https://www.ensembl.org/id/ENSGALP00010040839.1" } ] } }, { "isoform_ac": "A0A8V1AEW1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9H7/entry#A0A8V1AEW1-1", "sequence": { "sequence": "LGAAQACGRGAPRHTAAAAPSPRALGRALPGRSTATARWPAPDVLLLHGQAFSSGTWQALGTLALLAAEGHRAVAIDLPGYGDSPPAGSVATQRGRAAFLRHVVQRLGLRRPVLVSPSMSGRFALPFLLAHGRQLAGFVPIAPVGTREYGAVQYQQVQTPTLILYGDRDTGLGQQALQSLRHLPKHRVVVLPGAGHACYMDKPEDFHRALLGFLGQLQ", "length": 218, "header": "tr|A0A8V1AEW1-1|A0A8V1AEW1_CHICK Computationally mapped isoform of Protein ABHD14A OS=Gallus gallus OX=9031 GN= PE=1 SV=1 CANONICAL=A0A8V1A9H7-1" }, "locus": { "chromosome": "12", "start_pos": 3318360, "end_pos": 3316268, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066699.1", "url": "https://www.ensembl.org/id/ENSGALT00010066699.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040840.1", "url": "https://www.ensembl.org/id/ENSGALP00010040840.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9H7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9H7" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9H7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9H7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9H7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9H7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 65, "end_pos": 67, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": 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"field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A9N0-1", "uniprot_ac": "A0A8V1A9N0", "uniprot_id": "A0A8V1A9N0_CHICK", "mass": { "chemical_mass": 88097.0, "monoisotopic_mass": 88097.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "A0A8V1A9N0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9N0/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9N0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9N0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9N0", "locus": {} } ], "crossref": [ { "id": "A0A8V1A9N0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A9N0", "database": "AlphaFoldDB", "categories": [] }, { "id": "A0A8V1A4R9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4R9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A4R9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4R9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A9N0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9N0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A9N0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9N0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRTPPDASVRQRAPLGAHPQRLQRRAELRRRRPAGTSGPWAVRSAALSAGTARSVAPTPILARPGWVPVRRSEPEVRPFGRSSALHGGRSAAVRGWESGGSVGTGRDREHSSSAAHGSSMAPGSSMALYGTRQLYGTGQLYGTWQHYGTWQLYGTQHMAHGSSMAPGSSVAHSSSVAHGSSMAHSTWHMAALWHSMAHGSSMAHGTSMAHSSSAAHGSSMAPGSSMALCGTHCGTLCGTQQLHGTPWHTAAPWHCMAHSSSVAHSSSMALYGTRQLCGTLWHTAALWHCMAHGSSTALHGTQQLHGTIRHMATLWHCMTHGSSMALYGTSSTMALHGTQQLCGTVWHTAAPWHYAAHGNTMALYDTWQLHGTPWHTAALWHCMAHSSSMALYGTQQLCGTVWHTAALWHCMAHGSSVALHGTWQLCGTHYGTLCGTQQLHGTLWHAAAPWHCMAYGNTMALCGTQQLHGSPWHTAAPWHCMAHSSSVALYGTQQLRGTVWHTAAPWHCMAHSSSMALYGTQQLRGTVWHTAAPWHCMAHSSSMALYGTRQLHGTPWHTAALWHCMAQAALWHSMAHSSSMALYGTRQLHGTLWHTAALWHTAAPWHCMAHSSTMALYGTRQLCGTHYVTLCGTQQLHGSLWHTATPRHCMAHGSTMALYGTQQLCGTQQLCGTVWHTAAPWLSMAHSNSTALYGTRQLCGTPWHTAAPWHCTAHGNTMALCGTQQLHGSPWHTAAPWHYTAHGNTMALYGTQQLHGTLWHTAALWHCMAHGSSVALYGTQQLHGTVWHTAALWHCMAHGNFMALYGTRQLHGTL", "length": 814, "header": "tr|A0A8V1A9N0-1|A0A8V1A9N0_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1A9N0-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A4R9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9N0/entry#A0A8V1A4R9-1", "sequence": { "sequence": "MRTPPDASVRQRAPLGAHPQRLQRRAELRRRRPAGTSGPWAVRSAALSAGTARSVAPTPILARPGWVPVRRSEPEVRPFGRSSALHGGRSAAVRGWESGGSVGTGRDREHSSSAAHGSSMAPGSSMALYGTRQLYGTGQLYGTWQHYGTWQLYGTQHMAHGSSMAPGSSVAHSSSVAHGSSMAHSTWHMAALWHSMAHGSSMAHGTSMAHSSSAAHGSSMAPGSSMALCGTHCGTLCGTQQLHGTPWHTAAPWHCMAHSSSVAHSSSMALYGTRQLCGTLWHTAALWHCMAHGSSTALHGTQQLHGTIRHMATLWHCMTHGSSMALYGTSSTMALHGTQQLCGTVWHTAAPWHYAAHGNTMALYDTWQLHGTPWHTAALWHCMAHSSSMALYGTQQLCGTVWHTAALWHCMAHGSSVALHGTWQLCGTHYGTLCGTQQLHGTLWHIAAPWHCMAHGSSVALYGTRQLHGTPWHTAAPWHSMAHSSSMALYGTRQLCGTPWHTAALWHSMTRSSSMALYGIWQHYGTLWHTAAPWLSMAHGSSMALYGTQQLCGTVWHTAAPWHCMAHGSSMALYGTQQLHGTVWHTAAPWHCMAHGSSMALYGTQQLHGSLWHTAAPWHSMAHSSSVALYGTSSTMALHGTQQLHGTLWHTAAPWHSMAHSSSVAHGSSMALYGTQQHYGTVWHTAALWHTLCHTLWHTAAPWLSMAHGNSTALYGTR", "length": 718, "header": "tr|A0A8V1A4R9-1|A0A8V1A9N0_CHICK Computationally mapped isoform of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1A9N0-1" }, "locus": { "chromosome": "25", "start_pos": 770937, "end_pos": 768784, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066843.1", "url": "https://www.ensembl.org/id/ENSGALT00010066843.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040902.1", "url": "https://www.ensembl.org/id/ENSGALP00010040902.1" } ] } }, { "isoform_ac": "A0A8V1A9N0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9N0/entry#A0A8V1A9N0-1", "sequence": { "sequence": "MRTPPDASVRQRAPLGAHPQRLQRRAELRRRRPAGTSGPWAVRSAALSAGTARSVAPTPILARPGWVPVRRSEPEVRPFGRSSALHGGRSAAVRGWESGGSVGTGRDREHSSSAAHGSSMAPGSSMALYGTRQLYGTGQLYGTWQHYGTWQLYGTQHMAHGSSMAPGSSVAHSSSVAHGSSMAHSTWHMAALWHSMAHGSSMAHGTSMAHSSSAAHGSSMAPGSSMALCGTHCGTLCGTQQLHGTPWHTAAPWHCMAHSSSVAHSSSMALYGTRQLCGTLWHTAALWHCMAHGSSTALHGTQQLHGTIRHMATLWHCMTHGSSMALYGTSSTMALHGTQQLCGTVWHTAAPWHYAAHGNTMALYDTWQLHGTPWHTAALWHCMAHSSSMALYGTQQLCGTVWHTAALWHCMAHGSSVALHGTWQLCGTHYGTLCGTQQLHGTLWHAAAPWHCMAYGNTMALCGTQQLHGSPWHTAAPWHCMAHSSSVALYGTQQLRGTVWHTAAPWHCMAHSSSMALYGTQQLRGTVWHTAAPWHCMAHSSSMALYGTRQLHGTPWHTAALWHCMAQAALWHSMAHSSSMALYGTRQLHGTLWHTAALWHTAAPWHCMAHSSTMALYGTRQLCGTHYVTLCGTQQLHGSLWHTATPRHCMAHGSTMALYGTQQLCGTQQLCGTVWHTAAPWLSMAHSNSTALYGTRQLCGTPWHTAAPWHCTAHGNTMALCGTQQLHGSPWHTAAPWHYTAHGNTMALYGTQQLHGTLWHTAALWHCMAHGSSVALYGTQQLHGTVWHTAALWHCMAHGNFMALYGTRQLHGTL", "length": 814, "header": "tr|A0A8V1A9N0-1|A0A8V1A9N0_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1A9N0-1" }, "locus": { "chromosome": "25", "start_pos": 770937, "end_pos": 768300, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066840.1", "url": "https://www.ensembl.org/id/ENSGALT00010066840.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040899.1", "url": "https://www.ensembl.org/id/ENSGALP00010040899.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 58, "start_aa": "Thr", "end_pos": 58, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr58", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 688, "end_pos": 690, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 58 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 688, "end_pos": 690 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A778-1", "uniprot_ac": "A0A8V1A778", "uniprot_id": "A0A8V1A778_CHICK", "mass": { "chemical_mass": 24051.0, "monoisotopic_mass": 24051.0 }, "refseq": { "ac": "NP_001182523", "name": "transcription elongation factor A N-terminal and central domain-containing protein 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001182523" }, "gene_names": [ { "name": "TCEANC2", "type": "recommended", "evidence": [ { "id": "A0A8V1A778", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A778" } ] }, { "name": "C1orf83", "type": "synonym", "evidence": [ { "id": "NP_001182523", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001182523" } ] }, { "name": "TCEANC2", "type": "synonym", "evidence": [ { "id": "NP_001182523", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001182523" } ] } ], "protein_names": [ { "name": "Transcription elongation factor A N-terminal and central domain containing 2", "type": "synonym", "evidence": [ { "id": "A0A8V1A778", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A778/entry#names_and_taxonomy" } ] }, { "name": "transcription elongation factor A (SII) N-terminal and central domain containing 2", "type": "synonym", "evidence": [ { "id": "NP_001182523", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001182523" } ] }, { "name": "transcription elongation factor A N-terminal and central domain-containing protein 2", "type": "synonym", "evidence": [ { "id": "NP_001182523", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001182523" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: HAEL01001262.1, HAEK01012848.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000239.1. On Sep 23, 2021 this sequence version replaced NP_001182523.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001182523", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001182523" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A778", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A778" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TCEANC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A778", "locus": { "chromosome": "8", "start_pos": 24828563, "end_pos": 24824712, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010025342", "url": "https://www.ensembl.org/id/ENSGALG00010025342" } ] } } ], "crossref": [ { "id": "A0A8V1A778", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A778", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00183", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00183", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "424657", "url": "https://www.ncbi.nlm.nih.gov/gene/424657", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003617", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003617", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003618", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003618", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017923", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017923", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035441", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035441", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036575", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036575", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:424657", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424657", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QPKENLM", "url": "https://omabrowser.org/oma/group/QPKENLM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A4T6", "url": "https://www.orthodb.org/?gene=A0A8V1A4T6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A778", "url": "https://www.orthodb.org/?gene=A0A8V1A778", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11477", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11477", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11477:SF14", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11477:SF14", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07500", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07500", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08711", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08711", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001182523", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001182523", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1A4T6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4T6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A4T6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4T6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A778", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A778", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A778-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A778-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MERFVVRRARSPQSPRRARSEPRAYRQATLESLKRVVVVEDIKRWKAMLELPGQPRENLMEALGELKKKIPSKEVLLSTKIGHTVNRMRKHSDPDVAGLAKDVYTEWRASIKHHANRPSIEVRSDPKTEAFRKNARKLLCEALDLEIDHPLAENIEREAFHLSSRLISAPYRRMVRALVFSLKHRPETRAEVKTGTLTVPAFVQSHKK", "length": 208, "header": "tr|A0A8V1A778-1|A0A8V1A778_CHICK Isoform 1 of Transcription elongation factor A N-terminal and central domain containing 2 OS=Gallus gallus OX=9031 GN=TCEANC2 PE=4 SV=1 CANONICAL=A0A8V1A778-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A4T6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A778/entry#A0A8V1A4T6-1", "sequence": { "sequence": "MLSSASPSYVFLKSVASEVRASFRVILHVGLAPAGLKVYLAAEHQQDCCPVCASTSQSRVMCCLVSGHTVNRMRKHSDPDVAGLAKDVYTEWRASIKHHANRPSIEVRSDPKTEAFRKNARKLLCEALDLEIDHPLAENIEREAFHLSSRLISAPYRRMVRALVFSLKHRPETRAEVKTGTLTVPAFVQSHKK", "length": 193, "header": "tr|A0A8V1A4T6-1|A0A8V1A778_CHICK Computationally mapped isoform of Transcription elongation factor A N-terminal and central domain containing 2 OS=Gallus gallus OX=9031 GN=TCEANC2 PE=4 SV=1 CANONICAL=A0A8V1A778-1" }, "locus": { "chromosome": "8", "start_pos": 24827674, "end_pos": 24825279, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010061873.1", "url": "https://www.ensembl.org/id/ENSGALT00010061873.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038197.1", "url": "https://www.ensembl.org/id/ENSGALP00010038197.1" } ] } }, { "isoform_ac": "A0A8V1A778-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A778/entry#A0A8V1A778-1", "sequence": { "sequence": "MERFVVRRARSPQSPRRARSEPRAYRQATLESLKRVVVVEDIKRWKAMLELPGQPRENLMEALGELKKKIPSKEVLLSTKIGHTVNRMRKHSDPDVAGLAKDVYTEWRASIKHHANRPSIEVRSDPKTEAFRKNARKLLCEALDLEIDHPLAENIEREAFHLSSRLISAPYRRMVRALVFSLKHRPETRAEVKTGTLTVPAFVQSHKK", "length": 208, "header": "tr|A0A8V1A778-1|A0A8V1A778_CHICK Isoform 1 of Transcription elongation factor A N-terminal and central domain containing 2 OS=Gallus gallus OX=9031 GN=TCEANC2 PE=4 SV=1 CANONICAL=A0A8V1A778-1" }, "locus": { "chromosome": "8", "start_pos": 24827674, "end_pos": 24824717, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010061877.1", "url": "https://www.ensembl.org/id/ENSGALT00010061877.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038201.1", "url": "https://www.ensembl.org/id/ENSGALP00010038201.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:424657", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424657", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1WAX2-1", "protein_name": "Transcription elongation factor A N-terminal and central domain containing 2", "gene_name": "TCEANC2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDKFVIRTPRIQSSPQKKDPGGKIYKQATIESLKRVVVIEDIKRWKTMLELPDQTKENLVEVLRELKKKIPSREVLKSTRIGHTVNKMRQHSDSEVACLAREVYTEWRTFIEEHVDRPSIVVRSDPKTETLRKNAQKLLSEALELEMDHLLVENIERETFHLCSRLINGPYRRTVRALVFTLKHQAEIRAQVKNGTLPVGTFVQTHKK", "length": 208 }, "evidence": [ { "id": "A0A8V1A778", "url": "https://omabrowser.org/oma/group/A0A8V1A778/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "B0UYI1-1", "protein_name": "Transcription elongation factor A N-terminal and central domain-containing protein 2", "gene_name": "tceanc2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDKFVVRLPKDDMMKQESKHERNYKQATLESLRRVVVIEDIERYKSILELPGQPKENMIEALKELDKKVPSREVLKSTRIGHTVNNLRKHSDDPEIKSLAKEVYKHWRTFIEEHANKPSIEVRCDKQTESLRSNAKKLLSEAIEMKVDHELVENIEREVFHQSSRLVSGAYRRTVRALVFALKHKPELRVQVKDGKLPVNVFVKSYKKKS", "length": 210 }, "evidence": [ { "id": "A0A8V1A778", "url": "https://omabrowser.org/oma/group/A0A8V1A778/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1MBR2-1", "protein_name": "Transcription elongation factor A N-terminal and central domain containing 2", "gene_name": "TCEANC2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MDKFVIRTPRIQSSPQKKDPGGKIYKQATIESLKRVVVIEDIKRWKTMLELPDQSKENLVEALRELKKKIPSREVLKSTKIGHTVNKMRQHSDSEVACLAREVYTEWRTFIEKHVNRPSIEVRSDAKTETFRKNAQKLLSEALELEMDHLLVENIERETFHLCSRLINGPYRRTVRALVFTLKHRAEIREQVKSSMLPVGTFVQTHKK", "length": 208 }, "evidence": [ { "id": "A0A8V1A778", "url": "https://omabrowser.org/oma/group/A0A8V1A778/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3GTM0-1", "protein_name": "Transcription elongation factor A N-terminal and central domain-containing protein 2", "gene_name": "Tceanc2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDKFVIRTPRTQNSPQKKQLGGKVYKQATIESLKRVVVVEDIKRWKTMLELPDQTKENLVTALQELKKKIPSKEVLRSTKIGHIVNKMRKHSDPEVACLAKEVHTEWKTFFEKHLDRPSIEVRSDPKTESFRKNAQKLLSEALELKMDHLLVENIERETFHLCSRLINGPYRRTVRALVFTLKHRAEIREQVKSGALPVGTFVQTHKK", "length": 208 }, "evidence": [ { "id": "A0A8V1A778", "url": "https://omabrowser.org/oma/group/A0A8V1A778/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q5XIC7-1", "protein_name": "Transcription elongation factor A N-terminal and central domain-containing protein 2", "gene_name": "Tceanc2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDKFVIRTPRIQNSPKKKLKEKVYKQATIESLKRVVVIEDIKRWKTVLELPEQTKENLVAALQELKKKIPSREVLRSTRIGHAVNKVRRHSDPEVAGLAKEVYTEWKTFIENHLDRPSIEVHSDPKTESFRKNAQKLLSEALELKMDHLLVENIERETFHLCSRLINRPYRRTVRALVFTLKHRAEIREQVKSGTLPVGTFVQTHKK", "length": 207 }, "evidence": [ { "id": "A0A8V1A778", "url": "https://omabrowser.org/oma/group/A0A8V1A778/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8R2M0-1", "protein_name": "Transcription elongation factor A N-terminal and central domain-containing protein 2", "gene_name": "Tceanc2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDKFVIRTPRIQNSPKKKLGEKVYKQATIESLKRVVVIEDIKRWKTMLELPDQTKENLVAALQELKKKMPSREVLRSTRIGHAVNKMRRHSDPEVAGLAKEVYTEWKTFIEKHLDRPSIEVRSDPKTESFRKNAQKLLSEALELKMDHLLVENIERETFHLCSRLINGPYRRTVRALVFTLKHRAEIREQVKSGALPVGTFVQTHKK", "length": 207 }, "evidence": [ { "id": "A0A8V1A778", "url": "https://omabrowser.org/oma/group/A0A8V1A778/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A778", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A778" } ], "pmid": "" }, { "name": "transcription elongation by RNA polymerase II", "id": "GO:0006368", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006368", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A778", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A778" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A778", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A778" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "transcription elongation factor activity", "id": "GO:0003711", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003711", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A778", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A778" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1A778", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A778" }, { "id": "PS51319", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51319" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "TFIIS N-terminal", "eco_id": "ECO_0000259", "start_pos": 40, "end_pos": 114, "start_aa": "Glu", "end_aa": "His", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1A778", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A778" }, { "id": "PS51321", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51321" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "TFIIS central", "eco_id": "ECO_0000259", "start_pos": 131, "end_pos": 208, "start_aa": "Phe", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A795-1", "uniprot_ac": "A0A8V1A795", "uniprot_id": "A0A8V1A795_CHICK", "mass": { "chemical_mass": 231492.0, "monoisotopic_mass": 231492.0 }, "refseq": {}, "gene_names": [ { "name": "SETD1A", "type": "recommended", "evidence": [ { "id": "A0A8V1A795", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A795" } ] } ], "protein_names": [ { "name": "SET domain containing 1A", "type": "synonym", "evidence": [ { "id": "A0A8V1A795", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A795/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A795", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A795" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SETD1A", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A795", "locus": { "chromosome": "15", "start_pos": 5698368, "end_pos": 5657233, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010025349", "url": "https://www.ensembl.org/id/ENSGALG00010025349" } ] } } ], "crossref": [ { "id": "cd12549", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12549", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd19169", "url": 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Classification" ] }, { "id": "IPR035979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044570", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044570", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046341", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046341", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A4V1", "url": "https://www.orthodb.org/?gene=A0A8V1A4V1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A795", "url": "https://www.orthodb.org/?gene=A0A8V1A795", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45814", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45814", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45814:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45814:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00076", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00076", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00856", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00856", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF11764", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11764", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-8936459", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8936459", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9772755", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9772755", "database": "Reactome", "categories": [ "Enzyme 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"length": 2045, "header": "tr|A0A8V1A4V1-1|A0A8V1A795_CHICK Computationally mapped isoform of SET domain containing 1A OS=Gallus gallus OX=9031 GN=SETD1A PE=4 SV=1 CANONICAL=A0A8V1A795-1" }, "locus": { "chromosome": "15", "start_pos": 5697364, "end_pos": 5657341, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010061892.1", "url": "https://www.ensembl.org/id/ENSGALT00010061892.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038212.1", "url": "https://www.ensembl.org/id/ENSGALP00010038212.1" } ] } }, { "isoform_ac": "A0A8V1A795-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A795/entry#A0A8V1A795-1", "sequence": { "sequence": "MCRRRRAVRRSRRSQRSQRCIVGGRRRQQRAHTICGGSRKREAGAWRAVRAGNRPHVRRGARLLPPGDDRPPSAMSFREIKAGEKAKHPEDHGKKQSSSWINGMENSTQASTSVEKRNHHWRSYKLIIDPALKKGQHKLYRYDGQHFSMPNSGIAPVDCVRDPRIGRIWTKTKELELSVPKFKIDEFYVGPVPPKQVTFAKLNDNIRENFLTDMCKKYGEVEEVEILYNPKNKKHLGIAKVIFATVKGAREAVQHLHNTSVMGNIIHVELDTKGETRMRFYELLVNGLYTPQTLPVGTEQDASPTVNETLQLTDSLKRLKDSNLSSVGSSVTPNSSTPFSHDTAYSSCRQDTPNSFSQFTPQSQGTPHTPRLGTPFSQDSTYSSRQTTPVYHFGQDSGYKHRRHETKFTDAYNRRPGGHHYVHNSPGVFRGTEHQFSTFKSHQQEPVQFSHTPPLSHSSSSSYKSAFSPYQAPAVFPQSEEQPFAQTSREAEYRRPAPPPAEMVVESSAATSADFAPVKEKPEEPPPLPDSNSAPEPSAPSFSQTPERSETPGTPTMESEMQHNSLDSRIEMLLKEQRTKLPFLNEHDSDNEVRMEGSPISSSSSQLSPIPMYGSNSQPGYRAQTPSSRPSSTGLEDISPTPLPDSDDDEPIPGTASLNQNSRGTSEASMTPIDQLNRASKVETLEVKEMVPGDQTPTSEKMDESQHSSGEDMEISDDEMNSAPITSAECAKTIVVNSSVSNAAVMAPSIPPLPPPPGFPPLPPPPPPPPQPAFPMPPPLPPPPPPTHPAVTVPPPPLPAPPGVPPPHILPPLPPFHPGMFPVMQVDMISVLGNHWGGMPMSFQMQTQMLSRMMQAQNTYQYPPFMGGRMQFVNLPPYRPFSMGAALGRGQQWPPLPKFDPSVPPPGYEPKKEDPHKATVDGVLLVIVKELKAIMKRDLNRKMVEVVAFRAFDDWWDKKERLAKASLTPVKSGGELEEKPKPKDRITSCLLENWNKGEGLGYEGIGLGIGLRGAIRLPSFKVKRKEPPEAASAGDQKRIRPSTSVDDEDEESERDRDASDTTSDLSKKDAEAVGLRRRPARPLELDSEGEEGDETSGKEEESSSEKEEEQEEEGGLVKAAPGKEEEEDDDDEEDEDDDEDEEDEEDYEETGVETSDKEEEQDSEEEDAASPSSSKAEVESSDESEDSSEFESSSDSDEDDDEEEEEEEDEEEEEEEEVAEDQDREAMVAETEHEPASHELPDDKRETILELYPVDYMDATGLGLSEPALVEKDEGMEEVKAEESECDQVPEESIAAETLKQLVMERDQETKLALSPICRPVEEPEPIVMLEPEVQECPKPESQDEAGTVCLSTPVAVFGEARPSKSSFFSKSDDSCLETHVKTKLPSAVEEEDRLPRTPGREVVVHSETDILLLPAHKVPSSTVPLPSTPGKEESVVPPEKFPEQLMVTKTSIEEEIPRTPGRDILAKSSHPLGKSQSTDTVPATPGSDAPLTGSSLTLSSPQVPGSPFSYPSQSPGINSGIPRTPGRDFNFTPTFPEAGATIPCLLSGKKQSEDDLDEKPFKEPLGASLTISMNSVPSPIPFASPTQADFRTDMGLPPNEPIPIAALPCIPGDGRMPIEECKAEVKSVLLSPEAPVGASILPPPPPPSVLPKRRPGRPRRSPPSVLSLDMYSGKTIEPPPVPVALVESAMSKELLSAHPDAFYGLKDPEAVTLDFRNDSFHEKIAAETVAEKLPFKELENQWNEDFKEEEAHAKPKRQWRRQKKSPEHLPVIPSPEYSPPQPQFRPRSEFEEMTILYDIWNGGIDEEDIKFMCITYDRLLQQDNGMDWLNDTLWVFHPSTSFSTPKKKKRDDGMREHVTGCARSEGYYKIDKKDKLKYLNNSRAFAEEPPADTQGMSIPAQPHASTRAGSERRSEQRRLLSSFTGSCDSDLLKFNQLKFRKKKLKFCKSHIHDWGLFAMEPIAADEMVIEYVGQNIRQVIADMREKRYEDEGIGSSYMFRVDHDTIIDATKCGNFARFINHSCNPNCYAKVITVESQKKIVIYSKQHINVNEEITYDYKFPIEDVKIPCLCGSENCRGTLN", "length": 2082, "header": "tr|A0A8V1A795-1|A0A8V1A795_CHICK Isoform 1 of SET domain containing 1A OS=Gallus gallus OX=9031 GN=SETD1A PE=4 SV=1 CANONICAL=A0A8V1A795-1" }, "locus": { "chromosome": "15", "start_pos": 5698239, "end_pos": 5657341, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010061897.1", "url": "https://www.ensembl.org/id/ENSGALT00010061897.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038216.1", "url": "https://www.ensembl.org/id/ENSGALP00010038216.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1429, "start_aa": "Thr", "end_pos": 1429, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1429", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1485, "start_aa": "Thr", "end_pos": 1485, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1485", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 641, "start_aa": "Thr", "end_pos": 641, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr641", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 792, "start_aa": "Thr", "end_pos": 792, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr792", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-GGA-8936459", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8936459", "resource": "Reactome", "description": "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" }, { "id": "R-GGA-9772755", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9772755", "resource": "Reactome", "description": "Formation of WDR5-containing histone-modifying complexes" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A795", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A795" } ], "pmid": "" }, { "name": "histone H3K4 methyltransferase activity", "id": "GO:0042800", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042800", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A795", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A795" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A795", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A795" } ], "pmid": "" }, { "name": "chromosome", "id": "GO:0005694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005694", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A795", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A795" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A795", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A795" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A795", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A795" } ], "pmid": "" }, { "name": "Set1C/COMPASS complex", "id": "GO:0048188", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048188", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A795", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A795" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A795", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A795" } ], "pmid": "" }, { "name": "methylation", "id": "GO:0032259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032259", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A795", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A795" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 106, "end_pos": 108, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1531, "end_pos": 1533, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1718, "end_pos": 1720, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1831, "end_pos": 1833, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1881, "end_pos": 1883, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2021, "end_pos": 2023, "annotation": "n_glycosylation_sequon" }, { "start_pos": 258, "end_pos": 260, "annotation": "n_glycosylation_sequon" }, { "start_pos": 307, "end_pos": 309, "annotation": "n_glycosylation_sequon" }, { "start_pos": 323, "end_pos": 325, "annotation": "n_glycosylation_sequon" }, { "start_pos": 334, "end_pos": 336, "annotation": "n_glycosylation_sequon" }, { "start_pos": 737, "end_pos": 739, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1A795", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A795" }, { "id": "PS50868", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50868" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Post-SET", "eco_id": "ECO_0000259", "start_pos": 2066, "end_pos": 2082, "start_aa": "Val", "end_aa": "Asn", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1A795", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A795" }, { "id": "PS50102", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50102" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RRM", "eco_id": "ECO_0000259", "start_pos": 185, "end_pos": 273, "start_aa": "Asp", "end_aa": "Lys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1A795", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A795" }, { "id": "PS50280", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50280" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SET", "eco_id": "ECO_0000259", "start_pos": 1943, "end_pos": 2060, "start_aa": "Lys", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 641, 792, 1429, 1485 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 106, "end_pos": 108 }, { "start_pos": 1531, "end_pos": 1533 }, { "start_pos": 1718, "end_pos": 1720 }, { "start_pos": 1831, "end_pos": 1833 }, { "start_pos": 1881, "end_pos": 1883 }, { "start_pos": 2021, "end_pos": 2023 }, { "start_pos": 258, "end_pos": 260 }, { "start_pos": 307, "end_pos": 309 }, { "start_pos": 323, "end_pos": 325 }, { "start_pos": 334, "end_pos": 336 }, { "start_pos": 737, "end_pos": 739 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 4 }, { "field": "total_sites", "count": 4 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 4 }, { "field": 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"https://www.ncbi.nlm.nih.gov/protein/XP_040529234" } ] } ], "protein_names": [ { "name": "Ankyrin repeat and BTB/POZ domain-containing protein 2", "type": "recommended", "evidence": [ { "id": "A0A8V1A830", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A830/entry#names_and_taxonomy" } ] }, { "name": "ankyrin repeat and BTB/POZ domain-containing protein 2", "type": "synonym", "evidence": [ { "id": "XP_040529234", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040529234" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052577.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040529234", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040529234" } ] }, { "annotation": "May be involved in the initiation of hepatocyte growth.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A4Z5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Z5#function" }, { "database": "UniProtKB", "id": "ARBA00056228", "url": "https://www.uniprot.org/uniprotkb/ARBA00056228#function" }, { "database": "UniProtKB", "id": "A0A8V1A830", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A830#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A830", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A830" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ABTB2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A830", "locus": { "chromosome": "5", "start_pos": 18071644, "end_pos": 18204713, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010024886", "url": "https://www.ensembl.org/id/ENSGALG00010024886" } ] } } ], "crossref": [ { "id": "A0A8V1A830", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A830", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd18350", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18350", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd22913", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22913", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "425717", "url": "https://www.ncbi.nlm.nih.gov/gene/425717", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009072", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009072", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048063", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048063", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052089", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052089", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR059008", "url": "https://www.ebi.ac.uk/interpro/entry/IPR059008", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "LQCNGST", "url": "https://omabrowser.org/oma/group/LQCNGST/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A4Z5", "url": "https://www.orthodb.org/?gene=A0A8V1A4Z5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A830", "url": "https://www.orthodb.org/?gene=A0A8V1A830", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46071", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46071", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46071:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46071:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00023", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00023", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00651", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00651", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12796", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12796", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF26281", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26281", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040529234", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040529234", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1A4Z5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Z5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A4Z5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Z5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A830", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A830", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A830-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A830-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAGIYSSTLKTLEDLTLDSGYGAGDSCRSLSLSSSKSNSQAFTSSQHRGNWWYYSGSMNSRNNSWDTVNTVLPEDPEVADIFSKCPRLPDLEEYPWTDEDVARILRKAKGDGSGRPFSHEAVRRLSQLLRRALIRVSREAQRLSVMHSKCTRFEVQSAVKLIQSWSLAESCVLATVKALSLYSMSAGDGLRKGKSARCGLTFSVGRFFRWMVDTRISVRIHEYAAISLTACMENLVEEIKGRVLASQSPDGGGGEISAEILEVVINNDAELWGVLQPYEHLICGKNANGVLSLPAYFSPYNDGSVCSDGRADAYAQLELRTLEQSLLATCVGSISELSDLVSRAMHHMQCLNTIRPGMSPIRQTRQQQPISWSPDALHTLYYFLRCPQMESMENPNLDPPRMTLNNERPFMLLPPLMEWMRVAITYAEHRRSLTVDSDDIRQTARLLLPGLDCEPRQLKPECCFSSFRRLDAKAATEKFQQDLGFRMLNCGRTDLINQAIDALGADGVNTMDDQGMTPLMYACAAGDEAMVQMLIDAGANLDIPVPSTSPRYPSVHPDSRHWTALTFAVLHGHISVVQLLLDAGAHVEGSAVNSGEDNYAETPLQLASAAGNYELVSLLLSRGADPLLSMLEVNGMSSSLHEDMNCFSHSAAHGHRNVLRKLLTQPQQLKGDVLSLEEILAEGVESDTSSQGSSNEGQVKLCKTRMKALQEAMYYSAEHGYVDITMELRGLGVPWKLHVWIESLRTTFYQSRYSVVQTLLREFVTIKEEDYNEELVNEGLQLMFDILKTSKNDSINQQLASIFTHCYGSSPIPSIPEIHKTLPARLDPHFLNNKEMSDVTFLVEGKLFYAHKVLLVTASNRFKTLMTNKTEHDSHGSKTVEISDMKYNIFKMLMQYLYYGGTESMEIPTTDILELLSAASLFQLDGLQRHCEILCAQTISMENSVSIYKYAKIHNAPELAAFCEGFFLKHMSSLLEQDSFRQLIYSRNSKVQGLDPLRDLQTALAGRLHSVYVTSRV", "length": 1017, "header": "tr|A0A8V1A830-1|A0A8V1A830_CHICK Isoform 1 of Ankyrin repeat and BTB/POZ domain-containing protein 2 OS=Gallus gallus OX=9031 GN=ABTB2 PE=4 SV=1 CANONICAL=A0A8V1A830-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A4Z5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A830/entry#A0A8V1A4Z5-1", "sequence": { "sequence": "MAGIYSSTLKTLEDLTLDSGYGAGDSCRSLSLSSSKSNSQAFTSSQHRGNWWYYSGSMNSRNNSWDTVNTVLPEDPEVADIFSKCPRLPDLEEYPWTDEDVARILRKAKGDGSGRPFSHEAVRRLSQLLRRALIRVSREAQRLSVMHSKCTRFEVQSAVKLIQSWSLAESCVLATVKALSLYSMSAGDGLRKGKSARCGLTFSVGRFFRWMVDTRISVRIHEYAAISLTACMENLVEEIKGRVLASQSPDGGGGEISAEILEVVINNDAELWGVLQPYEHLICGKNANGVLSLPAYFSPYNDGSVCSDGRADAYAQLELRTLEQSLLATCVGSISELSDLVSRAMHHMQCLNTIRPGMSPIRQTRQQQPISWSPDALHTLYYFLRCPQMESMENPNLDPPRMTLNNERPFMLLPPLMEWMRVAITYAEHRRSLTVDSDDIRQTARLLLPGLDCEPRQLKPECCFSSFRRLDAKAATEKFQQDLGFRMLNCGRTDLINQAIDALGADGVNTMDDQGMTPLMYACAAGDEAMVQMLIDAGANLDIPVPSTSPRYPSVHPDSRHWTALTFAVLHGHISVVQLLLDAGAHVEGSAVNSGEDNYAETPLQLASAAGNYELVSLLLSRGADPLLSMLEVNGMSSSLHEDMNCFSHSAAHGHRNVLRKLLTQPQQLKGDVLSLEEILAEGVESDTSSQGSSNEGQVKLCKTRMKALQEAMYYSAEHGYVDITMELRGLGVPWKLHVWIESLRTTFYQSRYSVVQTLLREFVTIKEEDYNEELVNEGLQLMFDILKTSKNDSINQQLASIFTHCYGSSPIPSIPEIHKTLPARLDPHFLNNKEMSDVTFLVEGKLFYAHKVLLVTASNRFKTLMTNKTEHDSHGSKTVEISDMKYNIFKMLMQYLYYGGTESMEIPTTDILELLSAASLFQLDGLQRHCEILCAQTISMENSVSIYKYAKDLLERDALRSTSK", "length": 965, "header": "tr|A0A8V1A4Z5-1|A0A8V1A830_CHICK Computationally mapped isoform of Ankyrin repeat and BTB/POZ domain-containing protein 2 OS=Gallus gallus OX=9031 GN=ABTB2 PE=4 SV=1 CANONICAL=A0A8V1A830-1" }, "locus": { "chromosome": "5", "start_pos": 18204551, "end_pos": 18071671, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010060766.1", "url": "https://www.ensembl.org/id/ENSGALT00010060766.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010037525.1", "url": "https://www.ensembl.org/id/ENSGALP00010037525.1" } ] } }, { "isoform_ac": "A0A8V1A830-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A830/entry#A0A8V1A830-1", "sequence": { "sequence": "MAGIYSSTLKTLEDLTLDSGYGAGDSCRSLSLSSSKSNSQAFTSSQHRGNWWYYSGSMNSRNNSWDTVNTVLPEDPEVADIFSKCPRLPDLEEYPWTDEDVARILRKAKGDGSGRPFSHEAVRRLSQLLRRALIRVSREAQRLSVMHSKCTRFEVQSAVKLIQSWSLAESCVLATVKALSLYSMSAGDGLRKGKSARCGLTFSVGRFFRWMVDTRISVRIHEYAAISLTACMENLVEEIKGRVLASQSPDGGGGEISAEILEVVINNDAELWGVLQPYEHLICGKNANGVLSLPAYFSPYNDGSVCSDGRADAYAQLELRTLEQSLLATCVGSISELSDLVSRAMHHMQCLNTIRPGMSPIRQTRQQQPISWSPDALHTLYYFLRCPQMESMENPNLDPPRMTLNNERPFMLLPPLMEWMRVAITYAEHRRSLTVDSDDIRQTARLLLPGLDCEPRQLKPECCFSSFRRLDAKAATEKFQQDLGFRMLNCGRTDLINQAIDALGADGVNTMDDQGMTPLMYACAAGDEAMVQMLIDAGANLDIPVPSTSPRYPSVHPDSRHWTALTFAVLHGHISVVQLLLDAGAHVEGSAVNSGEDNYAETPLQLASAAGNYELVSLLLSRGADPLLSMLEVNGMSSSLHEDMNCFSHSAAHGHRNVLRKLLTQPQQLKGDVLSLEEILAEGVESDTSSQGSSNEGQVKLCKTRMKALQEAMYYSAEHGYVDITMELRGLGVPWKLHVWIESLRTTFYQSRYSVVQTLLREFVTIKEEDYNEELVNEGLQLMFDILKTSKNDSINQQLASIFTHCYGSSPIPSIPEIHKTLPARLDPHFLNNKEMSDVTFLVEGKLFYAHKVLLVTASNRFKTLMTNKTEHDSHGSKTVEISDMKYNIFKMLMQYLYYGGTESMEIPTTDILELLSAASLFQLDGLQRHCEILCAQTISMENSVSIYKYAKIHNAPELAAFCEGFFLKHMSSLLEQDSFRQLIYSRNSKVQGLDPLRDLQTALAGRLHSVYVTSRV", "length": 1017, "header": "tr|A0A8V1A830-1|A0A8V1A830_CHICK Isoform 1 of Ankyrin repeat and BTB/POZ domain-containing protein 2 OS=Gallus gallus OX=9031 GN=ABTB2 PE=4 SV=1 CANONICAL=A0A8V1A830-1" }, "locus": { "chromosome": "5", "start_pos": 18204551, "end_pos": 18078638, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010060764.1", "url": "https://www.ensembl.org/id/ENSGALT00010060764.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010037523.1", "url": "https://www.ensembl.org/id/ENSGALP00010037523.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "E1BMN7-1", "protein_name": "Ankyrin repeat and BTB/POZ domain-containing protein 2", "gene_name": "ABTB2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MIGGPPGLFACRQQPSTQLCRRLAPRRSLQRAFSQVGPGLAQRREPPPSIAAALFSRGPFSAENRRSASGKLRWTRRVAEEEQRRIVPVTARSRDAGSVGLWPPRISPTFLRPPGRRAGDAAAEPRGAERKEGAPESLELVSAHLGKGAWSCERPSLGEAAPGRLPMAGTYSSTLKTLEDLTLDSGYGAGDSCRSLSLSSSKSNSQALNSSAQQHRGAAWWCYSGSMNSRHNSWDTVNTVLPEDPEVADLFSRCPRLPELEEFPWTEGDVARVLRKGAGGRRQPLFSAEAVRRLAGLLRRALIRVAREAQRLSVLHAKCTRFEVQSAVRLVHSWALAESCALAAVKALSLYSMSAGDGLRRGKSARCGLTFSVGRFFRWMVDTRISVRIHEYAAISLTACMENLVEEIRARVLASQSPDGGGAGGGEVSAEALEMVINNDAELWGVLQPYEHLICGKNANGVLSLPAYFSPYNGGSLGHDERADAYAQLELRTLEQSLLATCVGSISELSDLVSRAMHHMQGRHPLCPGSSPARQARQPPQPITWSPDALHTLYYFLRCPQMESMENPNLDPPRMALNNERPFMLLPPLMEWMRVAITYAEHRRSLTVDSGDIRQAARLLLPGLDCEPRQLKPECCFSSFRRLDARAATEKFNQDLGFRMLNCGRTDLISQAIEALGPDGVNTMDDQGMTPLMYACAAGDEAMVQMLIDAGANLDIQVPSNSPRHPSIHPDSRHWTSLTFAVLHGHISVVQLLLDAGAHVEGSAVNGGEDSYAETPLQLASAAGNYELVSLLLSRGADPLLSMLEANGMASSLHEDMNCFSHSAAHGHRNVLRKLLTQPQQAKADVLSLEEILAEGVEDSDASSQGSGSEGPMRLSRTRTKALQEAMYYSAEHGYVDITMELRALGVPWKLHVWIESLRTSFSQSRYSVVQSLLRDFSSIKEEEYNEELVTEGLPLMFDILKTSKNDSVTQQLAAIFMHCYGSSPIPRIPELRKTLPARLDPHFLNNKEMSDVTFLVEGKLFYAHKVLLVTASNRFKTLMTNKSEQDGDGSKTIEIGDMKYHIFQMMMQYLYYGGTESMDIPTSDILELLSAASLFQLDALQRHCEILGSQTLSVDSAVNTYKYAKIHNAPELALFCEGFFLKHMKALLEQDSFRQLIYGRSSKVQGLDPLQDLQSTLAERVHSLYVTSRV", "length": 1191 }, "evidence": [ { "id": "A0A8V1A830", "url": "https://omabrowser.org/oma/group/A0A8V1A830/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1SGS8-1", "protein_name": "Ankyrin repeat and BTB/POZ domain-containing protein 2", "gene_name": "ABTB2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAGTYSSTLKTLEDLTLDSGYGAGDSCRSLSLSSSKSNSQALNSSAQQHRGAAWWCYSGSMNSRHNSWDTVNTVLPEDPEVADLFSRCPRLPELEEFPWTEGDVARVLRKGAGARRLPLFSAEAVRRLAGLLRRALIRVAREAQRLSVLHAKCTRFEVQSAVRLVHSWALAESCALAAVKALSLYSMSAGDGLRRGKSARCGLTFSVGRFFRWMVDTRISVRIHEYAAISLTACMENLVEEIRARVLASQSPDGGGAGGGEVSAEALEMVINNDAELWGVLQPYEHLICGKNANGVLSLPAYFSPYNGGSLGHDERADAYAQLELRTLEQSLLATCVGSISELSDLVSRAMHHMQGRHPLCPGSSPARQARQPPQPITWSPDALHTLYYFLRCPQMESMENPNLDPPRMALNNERPFMLLPPLMEWMRVAITYAEHRRSLTVDSGDIRQAARLLLPGLDCEPRQLKPECCFSSFRRLDARAATEKFNQDLGFRMLNCGRTDLISQAIEALGPDGVNTMDDQGMTPLMYACAAGDEAMVQMLIDAGANLDIQVPSNSPRYPSIHPDSRHWTSLTFAVLHGHISVVQLLLDAGAHVEGSAVNGGEDSFAETPLQLASAAGNYELVSLLLSRGADPLLSMLEANGIASSLHEDMNCFSHSAAHGHRNVLRKLLTQPQQAKADVLSLEEILAEGVEESDASSQGSGSEGPVRLSRTRTKALQEAMYYSAEHGYVDITMELRALGVPWKLHVWIESLRTSFSQSRYSVVQSLLRDFSSIKEEEYNEELVTEGLQLMFDILKTSKNDSVIQQLATIFTHCYGSSPIPSIPELRKTLPARLDPHFLNNKEMSDVTFLVEGKLFYAHKVLLVTASNRFKTLMTNKSEQDGDSSKTIEISDMKYHIFQMMMRYLYYGGTESMDIPTGDILELLSAASLFQLDALQRHCEILCSQTLSVESAVSTYKYAKIHNAPELALFCEGFFLKHMKALLEQDSFRQLIYGRSSKVQGLDPLQDLQSTLAERVHSLYVTSRV", "length": 1025 }, "evidence": [ { "id": "A0A8V1A830", "url": "https://omabrowser.org/oma/group/A0A8V1A830/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "M9PFY3-1", "protein_name": "BTB domain-containing protein", "gene_name": "CG33291", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MYCTKDCTCSLCRELRGYKPSDKKSAPSAPTLLSRMLNDNFILRRRGISLKNFQPQSLRNSEMLAQQMPVPRPPQTPSPTPIEELPDWATEDSSRAKKPNHKVVIYFGDSIHRGGQQSPLPSPKELHSQLLQEMSQKLKTSVAEEGLTGVEKVKKVQQMAGQPETSPPANDELPPYIESVQNGVINIRIEGNYRRASALVETVAKPTLAVVAPTKSECDCDAALGDNDDGNADDDSDDPGQDEAETDSCDWSYVQEWRRAAKRPTGNLPPNFVQHQAPSQVTGLPPVPPPQMQSPHQVQSQLPPSQTPLSSQKGLAVAMATPAPRVFKELAQQPNKGMPHKMVASSSSCSGGQANSSCKMPSPGTASKALIPQRAVAGPARLTVQSTPVKSQPPQLSGSLSQSQVSPNRPILGIPTTAANPTPPRIHQHDQFRALQRVQECHSSSDENRSSGHASMSDTGGHSSSPAGGMTLGPLPEDRLAAGVTNRSTRSRRHRGIMPGGKAPWSGTGLEDIKLAMLTLRSQTSSSTYSSLSAGSESSEPARRLGRYSSLETVVTSTSADEFVWVDSHNRLVELQHPPWSQQCILKVLRNGRCQQQAEHLAVEAVSRLGYLLQRALVRIAREIQRFSAGVGLCSKQEVVGALRVVLSSSLADSCTKACLRSAAMFAVPGESALKQSKSARAGLQLSVGRFYRWMTDARLGKFIHEYAAVYLCAGIENLLEEIALQCNGTTAAALDQSIASSGDVWGLLQPFAHLNAGRIASGALALPRWANSLDQVIASSGDFRGHLATCVGSIRELKEKALRTQQEFQLAAALSGSALAALFYFMRCSQLEHTELLAASGCHAGQAQSAAPGGGTSSAGHHVQELCYERAYVVLPPLAEWLRVAAAHAEHRNAMMIDKDDVMQAARLLLPGVDCPIRPVAHDEELPTKKTHFNTAPTVSSTGTGTGSSSCSSPVVSGIGIGIGEDTSELGRRATIGVAFKLLLTGRAELLAQAAQLLPPTTRYDTQNSAGLTALMIASIRNDEVALHALLDAGCDPNVEVPPAGSAGYPAIQPDTQHWTALSFAASRANYVALRILLERGGKVEGGARSSEEKCTLTPLQLAAGTGNLEIVALLLAHGANAFLSTQQKDSLCFAGSAQKGCFCAISVAAAHGHRSCLRKLLTHPVSPGTRDVLSLEEMLAEGDVGGVRGSGGPTGAGGPNSASASGNNEDILPLLNKTQIKRLQEAMYHSAENNHLDITIELRKLGVPWTLHCWMHALSAAHDLRLDAVIDQLLQDFLQVCPDDYSAQFVSECLPLLFNIFRNKNEGTTLLLADIFATCFGWETLPPVKEQPPMQPVQGSRIDPKFVNNPELSDVTFRVEGKIFYGHKIVLVTASPRFQSMLSSKLSEGSSTPTVQINDIRYHIFQLVMQFLYCGGCSSLDVAHGDVLELMAAASFFQLEGLLRYTEARCSEMVDVDNVVAMYIHAKVYNANRLLEFCQCFLLQNMVALLTYDDSVKRLLFAKKIPNHDVLAGLLQTLQNRLKARKPNSGGGLVNSYRSPPVTPVKK", "length": 1549 }, "evidence": [ { "id": "A0A8V1A830", "url": "https://omabrowser.org/oma/group/A0A8V1A830/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "O08764-1", "protein_name": "Ankyrin repeat and BTB/POZ domain-containing protein 2", "gene_name": "Abtb2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGTYSSTLKTLEDLTLDSGYGAGDSCRSLSLSSSKSNSQALNSSAPQHRGAAWWCYSGSMNSRHNSWDTVNTVLPEDPEVADLFSRCPRLPELEEFPWTEGDVARVLRKSVGGRRLPSFSAEAVRRLAGLLRRALIRVAREAQRLSVLHAKCTRFEVQSAVRLVHSWALAESCALAAVKALSLYSMSAGDGLRRGKSARCGLTFSVGRFFRWMVDTRISVRIHEYAAISLTACMENLVEEIRARVLASQSPDGGGAGGGEVSAEALEMVINNDAELWGVLQPYEHLICGKNANGVLSLPAYFSPYNGGSLGHDERADAYAQLELRTLEQSLLATCVGSISELSDLVSRAMHHMQGRHPLCPGTSPARQARQPPQPITWSPDALHTLYYFLRCPQMESMENPNLDPPRMTLNNERPFMLLPPLMEWMRVAITYAEHRRSLTVDSGDIRQAARLLLPGLDCEPRQLKPECCFSSFRRLDARAATERFNQDLGFRMLNCGRTDLISQPSSPGPDGVNTMDDQGLTPLMYACATGDEAMVQMLIDAGANLDIQVPSNSPRHPSVHPDSRHWTSLTFAVLHGHISVVQLLLDAGAHVEGSAVNSGEDSYAETPLQLASAAGNYELVSLLLSRGADPLLSMLEANGMASSLHEDMNCFSHSAAHGHRNVLRKLLTQPQQAKADVLSLEEILAEGVEESDTSSQGSSEGPVRLSRTRTKALQEAMYYSAEHGYVDITMELRALGVPWKLHIWIESLRTSFSQSRYSVVQGLLRDFSSIKEEEYNEELVTEGLQLMFDILKTSKNDSVLQQLATIFTHCYGTSPIPSIPEIRKTLPARLDPHFLNNKEMSDVTFLVEGKLFYAHKVLLVTASNRFKTLMTNKSEQDGDNSKTIEISDIKYHIFQMLMQYLYYGGTESMEIPTADILQLLSAANLFQLDALQRHCEILCSQTLSVESAVNTYKYAKIHNAPELALFCEGFFLKHMKALLEQMPSGSSSMAEAAKSRAWTHCRICRAP", "length": 1009 }, "evidence": [ { "id": "A0A8V1A830", "url": "https://omabrowser.org/oma/group/A0A8V1A830/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7TQI7-1", "protein_name": "Ankyrin repeat and BTB/POZ domain-containing protein 2", "gene_name": "Abtb2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAGTYSSTLKTLEDLTLDSGYGAGDSCRSLSLSSSKSNSQALNSSAQQHRGAAWWCYSGSMNSRHNSWDTVNTVLPEDPEVADLFSRCPRLPELEEFPWTEGDVARVLRKSVGGRRLPSFSAEAVRRLAGLLRRALIRVAREAQRLSVLHAKCTRFEVQSAVRLVHSWALAESCALAAVKALSLYSMSAGDGLRRGKSARCGLTFSVGRFFRWMVDTRISVRIHEYAAISLTACMENLVEEIRARVLASQSPDGGGAGGGEVSAEALEMVINNDAELWGVLQPYEHLICGKNANGVLSLPAYFSPYNGGSLGHDERADAYAQLELRTLEQSLLATCVGSISELSDLVSRAMHHMQGRHPLCPGTSPARQARQPPQPITWSPDALHTLYYFLRCPQMESMENPNLDPPRMTLNNERPFMLLPPLMEWMRVAITYAEHRRSPTVDSGDIRQAARLLLPGLDCEPRQLKPECCFSSFRRLDARAATERFNQDLGFRMLNCGRTDLISQAIEALGPDGVNTMDDQGMTPLMYACAAGDEAMVQMLIDAGANLDIQVPSHSPRHPSVHPDSRHWTSLTFAVLHGHISVVQLLLDAGAHVEGSAVNSGEDSYAETPLQLASAAGNYELVSLLLSRGADPLLSMLEANGMASSLHEEMNCFSHSAAHGHRNVLRKLLTQPQQAKADVLSLEEILAEGVEESDTSSQGSSEGPVRLSRTRTKALQEAMYYSAEHGYLDITMELRALGVPWKLHIWIESLRTSFSQSRYSVVQSLLKDFSSIKEEEYNEELVTEGLQLMFDILKTSKNDSVLQQLATIFTHCYGTSPIPSIPEIRKTLPARLDPHFLNNKEMSDVTFLVEGKLFYAHKVLLVTASNRFKTLMTNKSEQDGDSSKTIEISDIKYHIFQMLMQYLYYGGTESMEIPTADILQLLSAANLFQLDALQRHCEILCSQTLSVESAVNTYKYAKIHNAPELALFCEGFFLKHMKALLEQDAFRQLIYGRSSKVQGLDPLQDLQSTLAERVHSVYVTSRV", "length": 1024 }, "evidence": [ { "id": "A0A8V1A830", "url": "https://omabrowser.org/oma/group/A0A8V1A830/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8N961-1", "protein_name": "Ankyrin repeat and BTB/POZ domain-containing protein 2", "gene_name": "ABTB2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAGTYSSTLKTLEDLTLDSGYGAGDSCRSLSLSSSKSNSQALNSSAQQHRGAAWWCYSGSMNSRHNSWDTVNTVLPEDPEVADLFSRCPRLPELEEFPWTEGDVARVLRKGAGGRRLPQFSAEAVRRLAGLLRRALIRVAREAQRLSVLHAKCTRFEVQSAVRLVHSWALAESCALAAVKALSLYSMSAGDGLRRGKSARCGLTFSVGRFFRWMVDTRISVRIHEYAAISLTACMENLVEEIRARVMASHSPDGGGAGGGEVSAEALEMVINNDAELWGVLQPYEHLICGKNANGVLSLPAYFSPYNGGSLGHDERADAYAQLELRTLEQSLLATCVGSISELSDLVSRAMHHMQGRHPLCPGASPARQARQPPQPITWSPDALHTLYYFLRCPQMESMENPNLDPPRMTLNNERPFMLLPPLMEWMRVAITYAEHRRSLTVDSGDIRQAARLLLPGLDCEPRQLKPEHCFSSFRRLDARAATEKFNQDLGFRMLNCGRTDLINQAIEALGPDGVNTMDDQGMTPLMYACAAGDEAMVQMLIDAGANLDIQVPSNSPRHPSIHPDSRHWTSLTFAVLHGHISVVQLLLDAGAHVEGSAVNGGEDSYAETPLQLASAAGNYELVSLLLSRGADPLLSMLEAHGMGSSLHEDMNCFSHSAAHGHRNVLRKLLTQPQQAKADVLSLEEILAEGVEESDASSQGSGSEGPVRLSRTRTKALQEAMYYSAEHGYVDITMELRALGVPWKLHIWIESLRTSFSQSRYSVVQSLLRDFSSIREEEYNEELVTEGLQLMFDILKTSKNDSVIQQLATIFTHCYGSSPIPSIPEIRKTLPARLDPHFLNNKEMSDVTFLVEGKLFYAHKVLLVTASNRFKTLMTNKSEQDGDSSKTIEISDMKYHIFQMMMQYLYYGGTESMEIPTTDILELLSAASLFQLDALQRHCEILCSQTLSMESAVNTYKYAKIHNAPELALFCEGFFLKHMKALLEQDAFRQLIYGRSSKVQGLDPLQDLQNTLAERVHSVYITSRV", "length": 1025 }, "evidence": [ { "id": "A0A8V1A830", "url": "https://omabrowser.org/oma/group/A0A8V1A830/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein heterodimerization activity", "id": "GO:0046982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046982", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A830", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A830" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A830", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A830" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 62, "end_pos": 64, "annotation": "n_glycosylation_sequon" }, { "start_pos": 792, "end_pos": 794, "annotation": "n_glycosylation_sequon" }, { "start_pos": 868, "end_pos": 870, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1A830", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A830" }, { "id": "PS50097", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50097" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BTB", "eco_id": "ECO_0000259", "start_pos": 837, "end_pos": 906, "start_aa": "Ser", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 62, "end_pos": 64 }, { "start_pos": 792, "end_pos": 794 }, { "start_pos": 868, "end_pos": 870 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A7C2-1", "uniprot_ac": "A0A8V1A7C2", "uniprot_id": "A0A8V1A7C2_CHICK", "mass": { "chemical_mass": 46700.0, "monoisotopic_mass": 46700.0 }, "refseq": { "ac": "XP_015142288", "name": "guanine nucleotide exchange factor for Rab-3A isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015142288" }, "gene_names": [ { "name": "RAB3IL1", "type": "recommended", "evidence": [ { "id": "A0A8V1A7C2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7C2" } ] }, { "name": "RAB3IL1", "type": "synonym", "evidence": [ { "id": "XP_015142288", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015142288" } ] } ], "protein_names": [ { "name": "RAB3A interacting protein like 1", "type": "synonym", "evidence": [ { "id": "A0A8V1A7C2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7C2/entry#names_and_taxonomy" } ] }, { "name": "guanine nucleotide exchange factor for Rab-3A isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015142288", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015142288" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052536.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015142288.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015142288", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015142288" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7C2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7C2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RAB3IL1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7C2", "locus": { "chromosome": "5", "start_pos": 16351485, "end_pos": 16381742, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010025986", "url": "https://www.ensembl.org/id/ENSGALG00010025986" } ] } } ], "crossref": [ { "id": "A0A8V1A7C2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A7C2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000007203", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000007203", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd21069", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21069", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "423123", "url": "https://www.ncbi.nlm.nih.gov/gene/423123", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR009449", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009449", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040351", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040351", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:423123", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423123", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "EIDPIYH", "url": "https://omabrowser.org/oma/group/EIDPIYH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A4Z9", "url": "https://www.orthodb.org/?gene=A0A8V1A4Z9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A7C2", "url": "https://www.orthodb.org/?gene=A0A8V1A7C2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1C3B3", "url": "https://www.orthodb.org/?gene=E1C3B3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14430", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14430", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14430:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14430:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06428", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06428", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25555", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25555", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-8876198", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8876198", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015142288", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015142288", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1A4Z9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Z9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A4Z9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Z9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A7C2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7C2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A7C2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7C2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C3B3", "url": "https://www.uniprot.org/uniprotkb/E1C3B3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C3B3-1", "url": "https://www.uniprot.org/uniprotkb/E1C3B3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSLFSQTHFEEDSQEQPAVGYWKPLMPSKGSKEEPEAGCQDAGSGDDSQSTEQRNVSRLRSSSVEIREKGSEFLKEELHKAQKELKLKDKECERLSKVREQLEQELEELTASLFEEAHKMVREANTKQAASEKQLKEAWGKIDMLQAEVTALKTLVITSTPSSPNWELHPQLQSPSKAVFRKGHGRNKSTSSAVVTAVSQNATPTPVSRECKESGVPALLSLLLCIIPGKAIHFTYEPGWQALGADASSTLRQVDSILFAEFQSWKESPTLDKSCSFLDRIYREDVGPCLDFTKQELSELVRVAVEQNTLTIEPVASQMLPVVKVSAEDSGGPKKCALSGLPRTCKHRIMLGDSGNYYYISPSCRARITAVCNFFTYIRYIQQGLVRQDVELMYWEVMRLRREMSLAKLGFYPSEM", "length": 416, "header": "tr|A0A8V1A7C2-1|A0A8V1A7C2_CHICK Isoform 1 of RAB3A interacting protein like 1 OS=Gallus gallus OX=9031 GN=RAB3IL1 PE=1 SV=1 CANONICAL=A0A8V1A7C2-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A4Z9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7C2/entry#A0A8V1A4Z9-1", "sequence": { "sequence": "MSLFSQTHFEEDSQEQPAVGYWKPLMPSKGSKEEPEAGCQDAGSGDDSQSTEQRNVSRLRSSSVEIREKGSEFLKEELHKAQKELKLKDKECERLSKVREQLEQELEELTASLFEAHKMVREANTKQAASEKQLKEAWGKIDMLQAEVTALKTLVITSTPSSPNWELHPQLQSPSKAVFRKGHGRNKSTSSAVVTAVSQNATPTPVSRECKEVDSILFAEFQSWKESPTLDKSCSFLDRIYREDVGPCLDFTKQELSELVRVAVEQNTLTIEPVASQMLPVVKVSAEDSGGPKKCALSGLPRTCKHRIMLGDSGNYYYISPSCRARITAVCNFFTYIRYIQQGLVRQDVELMYWEVMRLRREMSLAKLGFYPSEM", "length": 375, "header": "tr|A0A8V1A4Z9-1|A0A8V1A7C2_CHICK Computationally mapped isoform of RAB3A interacting protein like 1 OS=Gallus gallus OX=9031 GN=RAB3IL1 PE=1 SV=1 CANONICAL=A0A8V1A7C2-1" }, "locus": { "chromosome": "5", "start_pos": 16365334, "end_pos": 16353442, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063379.1", "url": "https://www.ensembl.org/id/ENSGALT00010063379.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039118.1", "url": "https://www.ensembl.org/id/ENSGALP00010039118.1" } ] } }, { "isoform_ac": "A0A8V1A7C2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7C2/entry#A0A8V1A7C2-1", "sequence": { "sequence": "MSLFSQTHFEEDSQEQPAVGYWKPLMPSKGSKEEPEAGCQDAGSGDDSQSTEQRNVSRLRSSSVEIREKGSEFLKEELHKAQKELKLKDKECERLSKVREQLEQELEELTASLFEEAHKMVREANTKQAASEKQLKEAWGKIDMLQAEVTALKTLVITSTPSSPNWELHPQLQSPSKAVFRKGHGRNKSTSSAVVTAVSQNATPTPVSRECKESGVPALLSLLLCIIPGKAIHFTYEPGWQALGADASSTLRQVDSILFAEFQSWKESPTLDKSCSFLDRIYREDVGPCLDFTKQELSELVRVAVEQNTLTIEPVASQMLPVVKVSAEDSGGPKKCALSGLPRTCKHRIMLGDSGNYYYISPSCRARITAVCNFFTYIRYIQQGLVRQDVELMYWEVMRLRREMSLAKLGFYPSEM", "length": 416, "header": "tr|A0A8V1A7C2-1|A0A8V1A7C2_CHICK Isoform 1 of RAB3A interacting protein like 1 OS=Gallus gallus OX=9031 GN=RAB3IL1 PE=1 SV=1 CANONICAL=A0A8V1A7C2-1" }, "locus": { "chromosome": "5", "start_pos": 16365334, "end_pos": 16353442, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063381.1", "url": "https://www.ensembl.org/id/ENSGALT00010063381.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039120.1", "url": "https://www.ensembl.org/id/ENSGALP00010039120.1" } ] } }, { "isoform_ac": "E1C3B3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7C2/entry#E1C3B3-1", "sequence": { "sequence": "MSLFSQTHFEEDSQEQPAVGYWKPLMPSKGSKEEPEAGCQDAGSGDDSQSTEQRNVSRLRSSSVEIREKGSEFLKEELHKAQKELKLKDKECERLSKVREQLEQELEELTASLFEEAHKMVREANTKQAASEKQLKEAWGKIDMLQAEVTALKTLVITSTPSSPNWELHPQLQSPSKAVFRKGHGRNKSTSSAVVTAVSQNATPTPVSRECKEVDSILFAEFQSWKESPTLDKSCSFLDRIYREDVGPCLDFTKQELSELVRVAVEQNTLTIEPVASQMLPVVKVSAEDSGGPKKCALSGLPRTCKHRIMLGDSGNYYYISPSCRARITAVCNFFTYIRYIQQGLVRQDVELMYWEVMRLRREMSLAKLGFYPSEM", "length": 376, "header": "tr|E1C3B3-1|A0A8V1A7C2_CHICK Computationally mapped isoform of RAB3A interacting protein like 1 OS=Gallus gallus OX=9031 GN=RAB3IL1 PE=1 SV=1 CANONICAL=A0A8V1A7C2-1" }, "locus": { "chromosome": "5", "start_pos": 16365334, "end_pos": 16353442, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063383.1", "url": "https://www.ensembl.org/id/ENSGALT00010063383.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039122.1", "url": "https://www.ensembl.org/id/ENSGALP00010039122.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 205, "start_aa": "Thr", "end_pos": 205, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr205", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:423123", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423123", "resource": "KEGG Pathway" }, { "id": "R-GGA-8876198", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8876198", "resource": "Reactome", "description": "RAB GEFs exchange GTP for GDP on RABs" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A9J7GSF1-1", "protein_name": "Guanine nucleotide exchange factor for Rab-3A isoform X5", "gene_name": "Rab3il1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MWSGPPQPDEGLPTGLSAVSVPWKNLGPSKGHRESPGSLVENPASRKEAQGEEHSAAAPLDVSRLRSSSMEIREKGSEFLKEELYKAQKELKLKDEECERLCKVRAQLEQELEELTASLFQEAHKMVREANMKQAASEKQLKEAWGKIDMLQAEVTALKTLVITSTPASPNRELHPQLLSPTKAGPRKGHSRHKSTSSSLCPVVCPTAGHIPTPDKDGKEPGLPPLLSLLLCVIPSKAIHLTYEPTWQFPSGEPPTAPNSATSLSFSRQVDTTLFSEFQAWRASPTLDKDCPFLERVYREDVGPCLDFTVQELSALVRAAVEDNTLTIEPVASQTLPTVKVPTVECNNINTCALSGLARTCHHRIRLGDSESHYYISPSSRARITAVCNFFTYIRYIQQGLVRQDAEPMFWEIMRLRKGMSLAKLGFFPQEA", "length": 432 }, "evidence": [ { "id": "A0A8V1A7C2", "url": "https://omabrowser.org/oma/group/A0A8V1A7C2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q8TBN0-1", "protein_name": "Guanine nucleotide exchange factor for Rab-3A", "gene_name": "RAB3IL1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MWSGPPQPDQGLPPPLAAVPVPWKSTDPCQGHRESPGALVETSAGEEAQGQEGPAAAQLDVLRLRSSSMEIREKGSEFLKEELHRAQKELKLKDEECERLSKVREQLEQELEELTASLFEEAHKMVREANMKQAASEKQLKEARGKIDMLQAEVTALKTLVITSTPASPNRELHPQLLSPTKAGPRKGHSRHKSTSSTLCPAVCPAAGHTLTPDREGKEVDTILFAEFQAWRESPTLDKTCPFLERVYREDVGPCLDFTMQELSVLVRAAVEDNTLTIEPVASQTLPTVKVAEVDCSSTNTCALSGLTRTCRHRIRLGDSKSHYYISPSSRARITAVCNFFTYIRYIQQGLVRQDAEPMFWEIMRLRKEMSLAKLGFFPQEA", "length": 382 }, "evidence": [ { "id": "A0A8V1A7C2", "url": "https://omabrowser.org/oma/group/A0A8V1A7C2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8VDV3-1", "protein_name": "Guanine nucleotide exchange factor for Rab-3A", "gene_name": "Rab3il1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWSGQPQQDEGLPVGLSAIPVPWKNLGPSKSNRESSGGLVEASTSWEEAQGEEHPAPAPLDVSRLRSSSMEIREKGSEFLKEELYKAQKELKLKDEECERLCKVRAQLEQELEELTASLFEEAHKMVREANMKQATSEKQLKEAWGKIDMLQAEVTALKTLVITSTPASPNRELHPQLLSPTKAGPRKGHSRQKSTSSSLCPVVCPTAGHIPTPDKEGKEVDTTLFAEFQAWRASPTLDKSCPFLERVYREDVGPCLDFTVQELSALVRTAVEDNTLTIEPVASQTLPAVKVPTVECNNTNTCALSGLARTCHHRIRLGDSDSHYYISPSSRARITAVCNFFTYIRYIQQGLVRQDAEPMFWEIMRLRKGMSLAKLGFFPQEA", "length": 383 }, "evidence": [ { "id": "A0A8V1A7C2", "url": "https://omabrowser.org/oma/group/A0A8V1A7C2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q99NH3-1", "protein_name": "Guanine nucleotide exchange factor for Rab-3A", "gene_name": "Rab3il1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MWSGPPQQDEGLPVGLSAISVPWKNLGPSKGNRKSPGGLVEASASWEEAGGEEHPAAAPLDVSRLRSSSMEIREKGSEFLKEELYKAQKELKLKDEECERLCKVRAQLEQELEELTASLFEEAHKMVREANMKQAASEKQLKEAWGKIDMLQAEVTALKTLVITSTPASPNRELHPQLLSPTKAGPRKGHSRQKSTSSLCPVVCPTAGHIPTPDKEGKEVDTTLFAEFQAWRASPTLDKNCPFLERVYREDVGPCLDFTVQELSALVRTAVEDNTLTIEPVASQTLPNVECNNTNTCALSGLARTCHHRIRLGDSDGHYYISPSSRARITAVCNFFTYVRYIQQGLVRQDAEPMFWEIMRLRKGMSLAKLGFFPQEA", "length": 377 }, "evidence": [ { "id": "A0A8V1A7C2", "url": "https://omabrowser.org/oma/group/A0A8V1A7C2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7C2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7C2" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7C2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7C2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7C2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7C2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 187, "end_pos": 189, "annotation": "n_glycosylation_sequon" }, { "start_pos": 201, "end_pos": 203, "annotation": "n_glycosylation_sequon" }, { "start_pos": 55, "end_pos": 57, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1A7C2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7C2" }, { "id": "PF06428", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06428" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "GDP/GTP exchange factor Sec2 N-terminal", "eco_id": "ECO_0000259", "start_pos": 49, "end_pos": 146, "start_aa": "Gln", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 205 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 187, "end_pos": 189 }, { "start_pos": 201, "end_pos": 203 }, { "start_pos": 55, "end_pos": 57 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": 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domain-containing protein OS=Gallus gallus OX=9031 GN=LOC100857714 PE=4 SV=1 CANONICAL=A0A8V1A9Z3-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A531-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9Z3/entry#A0A8V1A531-1", "sequence": { "sequence": "MLWGRPDTFWCLLLTSFLQQASRVCAGDSTDVFGTEGKSATFHLQNLIGEYLTWSFHGEPILVIRLGARPELVFSDKSFTSRVTFSNNGSSLTILQLTRSDAGTYLAKSDEVKVNFTLHVYRELPEPMVICTGWNCSAESCRYELQCAVDPPGDNYFYWSYNNQPVNEGSEWVVERQHTEDPDLLPYTCTAQNPVSKRNTTVFPSALCAGTFSSSQNTIVVGLVIGLLLLLTVIVITVTLKGRRSHNLSVSAAPKAGAAAESMTVYAEVGANQQLRTDDEKMSSRMPGYCEQEKNPYSTVSELYPMAQPWGACVPAVSMDLLPATGEPSPSWTQGDELM", "length": 339, "header": "tr|A0A8V1A531-1|A0A8V1A9Z3_CHICK Computationally mapped isoform of Ig-like domain-containing protein OS=Gallus gallus OX=9031 GN=LOC100857714 PE=4 SV=1 CANONICAL=A0A8V1A9Z3-1" }, "locus": { "chromosome": "25", "start_pos": 1211557, "end_pos": 1206544, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067109.1", "url": "https://www.ensembl.org/id/ENSGALT00010067109.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041019.1", "url": "https://www.ensembl.org/id/ENSGALP00010041019.1" } ] } }, { "isoform_ac": "A0A8V1A9Z3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9Z3/entry#A0A8V1A9Z3-1", "sequence": { "sequence": "MLWGRPDTFWCLLLTSFLQQASRVCAGDSTDVFGTEGKSATFHLQNLIGEYLTWSFHGEPILVIRLGARPELVFSDKSFTSRVTFSNNGSSLTILQLTRSDAGTYLAKSDEVKVNFTLHVYRELPEPMVICTGWNCSAESCRYELQCAVDPPGDNYFYWSYNNQPVNEGSEWVVERQHTEDPDLLPYTCTAQNPVSKRNTTVFPSALCAGTFSSSQNTIVVGLVIGLLLLLTVIVITVTLKGRRSHNLSVSAAPKAGAAAESMTVYAEVGANQQIHVWNFPRAQKGDPKKLPASGVEISKTIYATVQDTTHLRTDDEKMSSRMPGYCEQEKNPYSTVSELYPMAQPWGACVPAVSMDLLPATGEPSPSWTQGDELM", "length": 376, "header": "tr|A0A8V1A9Z3-1|A0A8V1A9Z3_CHICK Isoform 1 of Ig-like domain-containing protein OS=Gallus gallus OX=9031 GN=LOC100857714 PE=4 SV=1 CANONICAL=A0A8V1A9Z3-1" }, "locus": { "chromosome": "25", "start_pos": 1211557, "end_pos": 1206544, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067112.1", "url": "https://www.ensembl.org/id/ENSGALT00010067112.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041021.1", "url": "https://www.ensembl.org/id/ENSGALP00010041021.1" } ] } }, { "isoform_ac": "A0A8V1ACQ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9Z3/entry#A0A8V1ACQ3-1", "sequence": { "sequence": "MLWGRPDTFWCLLLTSFLQQASRVCAGDSTDVFGTEGKSATFHLQNLIGEYLTWSFHGEPILVIRLGARPELVFSDKSFTSRVTFSNNGSSLTILQLTRSDAGTYLAKSDEVKVNFTLHVYRELPEPMVICTGWNCSAESCRYELQCAVDPPGDNYFYWSYNNQPVNEGSEWVVERQHTEDPDLLPYTCTAQNPVSKRNTTVFPSALCAESTASIPADGELPTVCVRSPNVTGSPSHHCHCHAAPTPRWRLGNLRYLLQQPKYNRSRTGDWTALTLDCHRYHCYIKRQEEPQPICFCSSQSRGCSREHDGVC", "length": 312, "header": "tr|A0A8V1ACQ3-1|A0A8V1ACQ3_CHICK Computationally mapped isoform of Ig-like domain-containing protein OS=Gallus gallus OX=9031 GN=LOC100857714 PE=4 SV=1 CANONICAL=A0A8V1A9Z3-1" }, "locus": { "chromosome": "25", "start_pos": 1210746, "end_pos": 1206544, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067107.1", "url": "https://www.ensembl.org/id/ENSGALT00010067107.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041018.1", "url": "https://www.ensembl.org/id/ENSGALP00010041018.1" } ] } }, { "isoform_ac": "A0A8V1AFC0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9Z3/entry#A0A8V1AFC0-1", "sequence": { "sequence": "MLWGRPDTFWCLLLTSFLQQASRVCAGDSTDVFGTEGKSATFHLQNLIGEYLTWSFHGEPILVIRLGARPELVFSDKSFTSRVTFSNNGSSLTILQLTRSDAGTYLAKSDEVKVNFTLHVYRELPEPMVICTGWNCSAESCRYELQCAVDPPGDNYFYWSYNNQPVNEGSEWVVERQHTEDPDLLPYTCTAQNPVSKRNTTVFPSALCAESTASIPADGELPTVCVRSPNVTGSPSHHCHCHAAPTPRWRLGNLRYLLQQPKYNRSRTGDWTALTLDCHRYHCYIKRQEEPQPICFCSSQSREGNRALRTSSKHGGLWGQEGARQGAEKSSSEVAVPHPEREMSPCSTCPS", "length": 351, "header": "tr|A0A8V1AFC0-1|A0A8V1AFC0_CHICK Computationally mapped isoform of Ig-like domain-containing protein OS=Gallus gallus OX=9031 GN=LOC100857714 PE=4 SV=1 CANONICAL=A0A8V1A9Z3-1" }, "locus": { "chromosome": "25", "start_pos": 1209916, "end_pos": 1206544, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067106.1", "url": "https://www.ensembl.org/id/ENSGALT00010067106.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041017.1", "url": "https://www.ensembl.org/id/ENSGALP00010041017.1" } ] } }, { "isoform_ac": "A0A8V1AHB0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9Z3/entry#A0A8V1AHB0-1", "sequence": { "sequence": "MLWGRPDTFWCLLLTSFLQQAMCAGDSTDVFGTEGKSATFHLQNLIGEYLTWSFHGEPILVIRLGARPELVFSDKSFTSRVTFSNNGSSLTILQLTRSDAGTYLAKSDEVKVNFTLHVYRELPEPMVICTGWNCSAESCRYELQCAVDPPGDNYFYWSYNNQPVNEGSEWVVERQHTEDPDLLPYTCTAQNPVSKRNTTVFPSALCAESTASIPADGTFSSSQNTIVVGLVIGLLLLLTVIVITVTLKGAAAESMTVYAEVGANQQIHVWNFPRAQKGDPKKLPASGVEISKTIYATVQDTTHLRTDDEKMSSRMPGYCEQEKNPYSTVSELYPMAQPWGACVPAVSMDLLPATGEPSPSWTQGDELM", "length": 368, "header": "tr|A0A8V1AHB0-1|A0A8V1A9Z3_CHICK Computationally mapped isoform of Ig-like domain-containing protein OS=Gallus gallus OX=9031 GN=LOC100857714 PE=4 SV=1 CANONICAL=A0A8V1A9Z3-1" }, "locus": { "chromosome": "25", "start_pos": 1211557, "end_pos": 1206544, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067111.1", "url": "https://www.ensembl.org/id/ENSGALT00010067111.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041020.1", "url": "https://www.ensembl.org/id/ENSGALP00010041020.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-202733", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-202733", "resource": "Reactome", "description": "Cell surface interactions at the vascular wall" }, { "id": "R-GGA-6798695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798695", "resource": "Reactome", "description": "Neutrophil degranulation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9Z3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9Z3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "immune response", "id": "GO:0006955", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006955", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9Z3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9Z3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 115, "end_pos": 117, "annotation": "n_glycosylation_sequon" }, { "start_pos": 135, "end_pos": 137, "annotation": "n_glycosylation_sequon" }, { "start_pos": 199, "end_pos": 201, "annotation": "n_glycosylation_sequon" }, { "start_pos": 247, "end_pos": 249, "annotation": "n_glycosylation_sequon" }, { "start_pos": 88, "end_pos": 90, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 115, "end_pos": 117 }, { "start_pos": 135, "end_pos": 137 }, { "start_pos": 199, "end_pos": 201 }, { "start_pos": 247, "end_pos": 249 }, { "start_pos": 88, "end_pos": 90 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AA09-1", "uniprot_ac": "A0A8V1AA09", "uniprot_id": "A0A8V1AA09_CHICK", "mass": { "chemical_mass": 120419.0, "monoisotopic_mass": 120419.0 }, "refseq": {}, "gene_names": [ { "name": "FAM120C", "type": "recommended", "evidence": [ { "id": "A0A8V1AA09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA09" } ] } ], "protein_names": [ { "name": "Family with sequence similarity 120 member C", "type": "synonym", "evidence": [ { "id": "A0A8V1AA09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA09/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AA09", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA09" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FAM120C", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA09", "locus": {} } ], "crossref": [ { "id": "A0A8V1AA09", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AA09", "database": "AlphaFoldDB", "categories": [] }, { "id": "415983", "url": "https://www.ncbi.nlm.nih.gov/gene/415983", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026784", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026784", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029060", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029060", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A545", "url": "https://www.orthodb.org/?gene=A0A8V1A545", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AA09", "url": "https://www.orthodb.org/?gene=A0A8V1AA09", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15976", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15976", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15976:SF14", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15976:SF14", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF27242", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27242", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1A545", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A545", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A545-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A545-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AA09", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA09", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AA09-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA09-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGVQGFQDYIEKHCPSAVVPTPLRLLIDADNCLHRLYGGFYTDWVSGGQWNHMLGYLAALAKACFNGNIELFVFFNGALEKARLHEWVKRQGNERQTAQQIVSHVQNKGTPPPKVWFLPPVCMAHCIRLALIRFHIKVAQSIEDHHQEVIAFCREKGFHGLVAYDSDYALCNIPYYFSAHALKLSRNGKSLTTSQYLMHEVAKQLDLNPNRFPIFAALLGNHILPDEDLASFHWSLLGPEHPLASLKVRAHQLVLPPCDVVIKAVADYVRNIQDTTDLDAIAKDVFQHSQSRTDDKVTRFKRAVAYYSATNKPMPFHPPHYIAARPNQFGMPGIVPPYVPSQMLNIPQTSLQAKPVAQQMSNQGGAQGQGPYPYSLSEPAITLETGGKNLSEQNNYSNIPHEGKHTPLYERSSPINPAQSGSPNHVDSTYFPASSTSSSSDNDEGNGGAVNHVSGNKIGWEKTGTQSESQTRGDLGDQTKAEGSSSASSGSQAADVKGNQTSNPQIPCLLSMPTRNHMDITTPPLPPVAPEVLRVAEHRHKKGLMYPYIFHVLTKGEIKIAVSIEDEANKDLPPAALLYRPVRQYVYGVLFSLAESRKKTERLAFRKNRLPPEFSPVIIKEWAAYKGKSPQTPELVEALAFREWTCPNLKKLWLGKAVEDKNRRMRAFLACMRSDTPAMLNPTNVPTHLMVLCCVLRYMVQWPGVRILRRQELDAFLAQALSPKLYEPDQLQELKIENLDPRGIQLSALFMSGVDMALFANDACGQPIPWEHCCPWMYFDGKLFQTKLIKASREKVPLIDLCDGQAEQAAKVEKMRQSILEGLNFSRQNHPLPFPPPPAMPFYPASMYPRHFGPVPPPQGRGRGFAGVYGFGGPYGETVATGAYRAFRVAAAAGHSGAFSGNDSNRTSKFQGGVQPIPSQGGKLEIAGTVVGHWAGSRRGRGGRGPFPLQVVSVGGPARGRPRGVISTPVIRTFGRGGRYYGRGYKSQGAIQGKPPYAASAEEVAKELKSKSEESKSSIVSSDGSLAENGVVNEEKPASQMNGNTGDIRASNQSESALSNDSKMCNTNPHLNALNADSVCHKDDALEATVLKKEE", "length": 1095, "header": "tr|A0A8V1AA09-1|A0A8V1AA09_CHICK Isoform 1 of Family with sequence similarity 120 member C OS=Gallus gallus OX=9031 GN=FAM120C PE=1 SV=1 CANONICAL=A0A8V1AA09-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A545-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA09/entry#A0A8V1A545-1", "sequence": { "sequence": "MGVQGFQDYIEKHCPSAVVPVELQKLARGSLVGGGRQRPPQTPLRLLIDADNCLHRLYGGFYTDWVSGGQWNHMLGYLAALAKACFNGNIELFVFFNGALEKARLHEWVKRQGNERQTAQQIVSHVQNKGTPPPKVWFLPPVCMAHCIRLALIRFHIKVAQSIEDHHQEVIAFCREKGFHGLVAYDSDYALCNIPYYFSAHALKLSRNGKSLTTSQYLMHEVAKQLDLNPNRFPIFAALLGNHILPDEDLASFHWSLLGPEHPLASLKVRAHQLVLPPCDVVIKAVADYVRNIQDTTDLDAIAKDVFQHSQSRTDDKVTRFKRAVAYYSATNKPMPFHPPHYIAARPNQFGMPGIVPPYVPSQMLNIPQTSLQAKPVAQQMSNQGGAQGQGPYPYSLSEPAITLETGGKNLSEQNNYSNIPHEGKHTPLYERSSPINPAQSGSPNHVDSTYFPASSTSSSSDNDEGNGGAVNHVSGNKIGWEKTGTQSESQTRGDLGDQTKAEGSSSASSGSQAADVKGNQTSNPQIPCLLSMPTRNHMDITTPPLPPVAPEVLRVAEHRHKKGLMYPYIFHVLTKGEIKIAVSIEDEANKDLPPAALLYRPVRQYVYGVLFSLAESRKKTERLAFRKNRLPPEFSPVIIKEWAAYKGKSPQTPELVEALAFREWTCPNLKKLWLGKAVEDKNRRMRAFLACMRSDTPAMLNPTNVPTHLMVLCCVLRYMVQWPGVRILRRQELDAFLAQALSPKLYEPDQLQELKIENLDPRGIQLSALFMSGVDMALFANDACGQPIPWEHCCPWMYFDGKLFQTKLIKASREKVPLIDLCDGQAEQAAKVEKMRQSILEGLNFSRQNHPLPFPPPPAMPFYPASMYPRHFGPVPPPQGRGRGFAGVQPIPSQGGKLEIAGTVVGHWAGSRRGRGGRGPFPLQVVSVGGPARGRPRGVISTPVIRTFGRGGRYYGRGYKSQGAIQGKPPYAASAEEVAKELKSKSEESKSSIVSSDGSLAENGVVNEEKPASQMNGNTGDIRASNQSESALSNDSKMCNTNPHLNALNADSVCHKDDALEATVLKKEE", 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"database": "AlphaFoldDB", "categories": [] }, { "id": "IPR018615", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018615", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044884", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044884", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A5A9", "url": "https://www.orthodb.org/?gene=A0A8V1A5A9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A7N2", "url": "https://www.orthodb.org/?gene=A0A8V1A7N2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A7N7", "url": "https://www.orthodb.org/?gene=A0A8V1A7N7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR34095", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR34095", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR34095:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR34095:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF09776", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09776", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-5389840", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5389840", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5419276", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5419276", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9937383", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9937383", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1A5A9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5A9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A5A9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5A9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A7N2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7N2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A7N2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7N2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A7N7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7N7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A7N7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7N7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVTQPPPWVEDILKEVEHTLKGIGREQHGLPSASSSPHQTAPVPSVSPHRPYSPSPSPALLPFPGPTPAPPCPLCTEAPKTERRSRGCPQEAALHPLAQSTMAAVWRVLSALQPRCLHTACGHRNSNRTSVTHLRRQVYGRLYPLLLVRTDGSTIHIRYKEPKRILMLPVDSSTLPEAERKARLRRQFPSKLRAKQEEALEELDLEKYKKFWKK", "length": 214, "header": "tr|A0A8V1A7N7-1|A0A8V1A7N7_CHICK Isoform 1 of Mitochondrial ribosomal protein L55 OS=Gallus gallus OX=9031 GN=MRPL55 PE=1 SV=1 CANONICAL=A0A8V1A7N7-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A5A9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7N7/entry#A0A8V1A5A9-1", "sequence": { "sequence": "MRFMAVSHRLPTELVMPHPCSHWSALQPRCLHTACGHRNSNRTSVTHLRRQVYGRLYPLLLVRTDGSTIHIRYKEPKRILMLPVDSSTLPEAERKARLRRQFPSKLRAKQEEALEELDLEKYKKFWKK", "length": 128, "header": "tr|A0A8V1A5A9-1|A0A8V1A7N7_CHICK Computationally mapped isoform of Mitochondrial ribosomal protein L55 OS=Gallus gallus OX=9031 GN=MRPL55 PE=1 SV=1 CANONICAL=A0A8V1A7N7-1" }, "locus": { "chromosome": "2", "start_pos": 2380068, "end_pos": 2379451, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063547.1", "url": "https://www.ensembl.org/id/ENSGALT00010063547.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039227.1", "url": "https://www.ensembl.org/id/ENSGALP00010039227.1" } ] } }, { "isoform_ac": "A0A8V1A7N2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7N7/entry#A0A8V1A7N2-1", "sequence": { "sequence": 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"MVTQPPPWVEDILKEVEHTLKGIGREQHGLPSASSSPHQTAPVPSVSPHRPYSPSPSPALLPFPGPTPAPPCPLCTEAPKTERRSRGCPQEAALHPLAQSTMAAVWRVLSALQPRCLHTACGHRNSNRTSVTHLRRQVYGRLYPLLLVRTDGSTIHIRYKEPKRILMLPVDSSTLPEAERKARLRRQFPSKLRAKQEEALEELDLEKYKKFWKK", "length": 214, "header": "tr|A0A8V1A7N7-1|A0A8V1A7N7_CHICK Isoform 1 of Mitochondrial ribosomal protein L55 OS=Gallus gallus OX=9031 GN=MRPL55 PE=1 SV=1 CANONICAL=A0A8V1A7N7-1" }, "locus": { "chromosome": "2", "start_pos": 2380068, "end_pos": 2377032, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063551.1", "url": "https://www.ensembl.org/id/ENSGALT00010063551.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039229.1", "url": "https://www.ensembl.org/id/ENSGALP00010039229.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true 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"pro_annotation": [], "site_annotation": [ { "start_pos": 127, "end_pos": 129, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 67 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 127, "end_pos": 129 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AA76-1", "uniprot_ac": "A0A8V1AA76", "uniprot_id": "A0A8V1AA76_CHICK", "mass": { "chemical_mass": 375927.0, "monoisotopic_mass": 375927.0 }, "refseq": {}, "gene_names": [ { "name": "LOC101751678", "type": "recommended", "evidence": [ { "id": "A0A8V1AA76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA76" } ] } ], "protein_names": [ { "name": "EF-hand domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8V1AA76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA76/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AA76", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA76" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC101751678", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA76", "locus": {} } ], "crossref": [ { "id": "cd00213", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00213", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR002048", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002048", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013787", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013787", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034325", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034325", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A5B8", "url": "https://www.orthodb.org/?gene=A0A8V1A5B8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AA76", "url": "https://www.orthodb.org/?gene=A0A8V1AA76", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AA88", "url": "https://www.orthodb.org/?gene=A0A8V1AA88", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AD08", "url": "https://www.orthodb.org/?gene=A0A8V1AD08", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AFL2", "url": "https://www.orthodb.org/?gene=A0A8V1AFL2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AFL7", "url": "https://www.orthodb.org/?gene=A0A8V1AFL7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AFM3", "url": "https://www.orthodb.org/?gene=A0A8V1AFM3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AHI1", "url": "https://www.orthodb.org/?gene=A0A8V1AHI1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AHI8", "url": "https://www.orthodb.org/?gene=A0A8V1AHI8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AHJ2", "url": "https://www.orthodb.org/?gene=A0A8V1AHJ2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11639", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11639", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11639:SF26", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11639:SF26", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01023", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01023", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1A5B8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5B8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A5B8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5B8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AA76", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA76", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AA76-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA76-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AA88", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA88", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AA88-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA88-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AD08", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD08", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AD08-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD08-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFL2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFL2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFL2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFL2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFL7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFL7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFL7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFL7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFM3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFM3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFM3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFM3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHI1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHI1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHI1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHI1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHI8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHI8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHI8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHI8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHJ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHJ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHJ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHJ2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSHFLDSVSTIITVFYQHAKEDGDQSKLNRRKMKEFIEKEFADAIVNPHDPQTIEKILQFLEWDGDGEIDFNEFLLLVFRVAKACYWYLQKGQCLLQRTKLITSSKTIQEPEIKNRGSRQQLQEEEPQTLERNRHPPCIPEPQPDTRVQDLETHEETGSHRQQHNTQSRADARQSTRPSEIIPQEYEEQTQEPCDQRSRQRRQPPELDRLGDLQSHKHGSLKAAQNDERQNQEKPQREQLADVRSCSHSCEPQLLPDRRSDRQPREPALPAYDQRNHRPQDQEAVAHGRSSRRPHEPEEADRGRHNQPRNPELLKDERSRNHLRKLEQKELERSSRQPCKPECLDSERLHQSYLQEPLVISHKYNNTRELEEDYYEQGKTQKDRKSCESMMEERTQEDSVAEAEATVKIRRETQKREREEEAKRPRESARYQRTQENTVAEAEADVEIHRVSRGRERELEDRRPHESVRHVKTQENIVAEAEADVEIRRVSREREREQEDRRPRDSERYDRTREDIVAEAEANVEIRRVSRGREREEDRRPDELVRYVKTQEDIVAEAEADVQIPCVSRKREREGKLRRPRESVRYERTREDIAAEAEADVEIRHVTQKRETGQEDRKPRESQRYDKTREDVVAEAEADVEIRRVSRGREREQEDRRPRESQSYERTREDIAAEAEADVEIHRVSRERKREEEARRPRELLRSGQRWEDIVAEAEADVEIHRVSREREREEEARRPRDSVRYERTREDVVAEAEADVEIRRVSRGREREQEDRRPRESQRYERTREDIAAEAEADVEIRRVSQGREREQEDRRPRESQRYERTREDIVAEAEADVEIRRVSRGREREEARRPHQLVRYVKTQEDLVAEAEANVEIHRVSREREREEEARRPRDSVRYERTREDIAAEAEADVEIRRVSRGREREEARRPNELVRYVKTQEDTVAEAEADVEIHHVSREREREEEARRPRDSVRYERTREDIVAEAEADVEIRRVSRGREREQEDRRPRESQRHERTREDIAAEAEANVEIRRVSRERKREEEARRPRDSVRYERTREDTVAEAEADVEIRRVSRGREREEARRPCELVRYVKTQEDIVAEAEADVEIHRVSREREREEEARRPRDSVRYERTREDIAAEAEADVEIRRVSRGREREQEDRRPRESQRYERTREDIVAEAEADVEIRRVSRGREREQDDRRPRESQRYERTREDIVAEAEAEVEIHRVSRGREREEARRPDDSVRYVKTQEDIVAEAEADVEIRRVSREREREEEARRPRDSVRYERTREDIVAEADLEIRRVSRERKREEEARRPRESQRYERTREDIVAEAEADVEIRRVSRGREREEARRPRESVRYVKTQEDIVAEAEADVEIYRVSREREREEARRPRDSVRYDRTREDIAAEAEADVEICRVSRGREREEARRPNELVRYVKTQEDTVAEAEADVEIHRVSREREREEEARRPRDSVRYERTREDIVAEAEADVEIRRVSRGREREQEDRRPRESQRYERTQEDIVAEAEADVEIRRVSRGREREQEDRRPHKSQRYERTREDIAAEAEADVEIRRVSRGREREQEDRRPRESQRYERTREDIVAEAEADVEIRRVSRGREREEARRPRDSVRYERTREDIVAEAEADVEIHRVSREREREEEARRPRDSVRYERTREDIVAEAEADVEIRRVSQGREREQEARRPCESQRYERTREDIVAEAEADVEIRRVSRGREREQDDRRPRESQRYERTREDIVAEAEAEVEIHRASRGREREEARRPDDSVRYVKTREDIVAEAEAEVEIRRVSREREREEEARRPRDSVRYERTQENIVAEAEADVEIRRVSRGREREQEDRRPRESQRYERTREDIVAEAEADVEIRRVSREREREEEARRPRDSVRYERTREDIVAEADLEIRRVSREREREEEARRPRESQRYERTREDIVAEAEADVEIRRVSRGREREEARRPRESVRYVKTQEDIVAEAEADVEIYRVSREREREEARRPRDSVRYERTREDIAAEAEADVEIRRVSRGREREEARRPNELVRYVKTQEDTVAEAEADVEIHRVSREREREEEARRPRDSVRYERTREDIAAEAEADVEIRRASQGREREQEDRRPHKSQRYERTREDIAAEAEADVEIRRVSRGREREEARRPCELVRYVKTQEDIVAEAEADVEIHRVSREREREEEARRPRDSVRYERTREDIVAEAEADVKIRRVSRGREREQEDRRPRESQRYERTWEDIVAEAEAEVEIHRASRGREREEARRPDDSVRYVKTREDIVAEAEADVEIRRVSQGREREQEARRPRESQRYERTREDIVAEAEAEVEIRRVSRGREREEARRPNELVRYVKTREDIVAEAEADVEIRRVSRGREREQEARRPRESQRYERTREDIVAEAEADVEIRRVSQERERQEEARRPRDSVRYDRTREDIVAEAEADVEIRHVTQKREREQEDRRPRKSQRYERTREDIVAEAEAEVEIRRVSRGREREEARRPNELVRYVKTREDSVAEAEAEVEIRRVSREREREEEARRPRDSVRYERTREDIVAEADLEIRWVSRERKREEEARRPRESQRYERTREDIVAEAEADVEIHRVTREREREEARKPRDSVRYERTREDIVAEAEADVEIRRVSRGREREQEDRRPHESQRYERTREDIVAEADVQIHRVSQKREREQEARRPRESVRYEKTQEDILAEAEADVEIRHVSREREREEARRPRESLRYERTQEDIVTDAEAEVCREEVERADSLHEYEEAVKERRAVRSRAREEAPVRERRLDRQRDLEVERNRFPVRDDQGERQERSLYQTVDVDSRDLVPPGEVPSVTDVRVRYIPSDPDVRPEVQAVPEPCEPQSIAYLIHVIQNLNDPKATTYEIICQQSNDSGQPVYVRKCYVSPQPPVGPCKESSVLEPELQHLPSSSSQENARELEEPRKGEIRERSATGVKEGASAPELDSLKDDTSQAETREDRRDHQSPSVHDVEEKNHQPEGDGPKATEEEVSQEAESQGNKDREAKSRSPAARAPELQEAHKQGQQAAEEPRHPVPQRDEAGCCHEDAELPSPDRSRQAREEENSKRSSQQENNTQPQREEERSPMAPQALSHPMRDEAKAP", "length": 3130, "header": "tr|A0A8V1AA76-1|A0A8V1AA76_CHICK Isoform 1 of EF-hand domain-containing protein OS=Gallus gallus OX=9031 GN=LOC101751678 PE=4 SV=1 CANONICAL=A0A8V1AA76-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A5B8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA76/entry#A0A8V1A5B8-1", "sequence": { "sequence": "MSHFLDSVSTIITVFYQHAKEDGDQSKLNRRKMKEFIEKEFADAIVNPHDPQTIEKILQFLEWDGDGEIDFNEFLLLVFRVAKACYWYLQKGQCLLQRTKLITSSKTIQEPEIKNRGSRQQLQEEEPQTLERNRHPPCIPEPQPDTRVQDLETHEETGSHRQQHNTQSRADARQSTRPSEIIPQEYEEQTQEPCDQRSRQRRQPPELDRLGDLQSHKHGSLKAAQNDERQNQEKPQREQLADVRSCSHSCEPQLLPDRRSDRQPREPALPAYDQRNHRPQDQEAVAHGRSSRRPHEPEEADRGRHNQPRNPELLKDERSRNHLRKLEQKELERSSRQPCKPECLDSERLHQSYLQEPLVISHKYNNTRELEEDYYEQGKTQKDRKSCESMMEERTQEDSVAEAEATVKIRRETQKREREEEAKRPRESARYQRTQENTVAEAEADVEIHRVSRGRERELEDRRPHESVRHVKTQENIVAEAEADVEIRRVSREREREQEDRRPRDSERYDRTREDIVAEAEANVEIRRVSRGREREEDRRPDELVRYVKTQEDIVAEAEADVQIPCVSRKREREGKLRRPRESVRYERTREDIAAEAEADVEIRHVTQKRETGQEDRKPRESQRYDKTREDVVAEAEADVEIRRVSRGREREQEDRRPRESQSYERTREDIAAEAEADVEIHRVSRERKREEEARRPRELLRSGQRWEDIVAEAEADVEIHRVSREREREEEARRPRDSVRYERTREDVVAEAEADVEIRRVSRGREREQEDRRPRESQRYERTREDIAAEAEADVEIRRVSQGREREQEDRRPRESQRYERTREDIVAEAEADVEIRRVSRGREREEARRPHQLVRYVKTQEDLVAEAEANVEIHRVSREREREEEARRPRDSVRYERTREDIAAEAEADVEIRRVSRGREREEARRPNELVRYVKTQEDTVAEAEADVEIHHVSREREREEEARRPRDSVRYERTREDIVAEAEADVEIRRVSRGREREQEDRRPRESQRHERTREDIAAEAEANVEIRRVSRERKREEEARRPRDSVRYERTREDTVAEAEADVEIRRVSRGREREEARRPCELVRYVKTQEDIVAEAEADVEIHRVSREREREEEARRPRDSVRYERTREDIAAEAEADVEIRRVSRGREREQEDRRPRESQRYERTREDIVAEAEADVEIRRVSRGREREQDDRRPRESQRYERTREDIVAEAEAEVEIHRVSRGREREEARRPDDSVRYVKTQEDIVAEAEADVEIRRVSREREREEEARRPRDSVRYERTREDIVAEADLEIRRVSRERKREEEARRPRESQRYERTREDIVAEAEADVEIRRVSRGREREEARRPRESVRYVKTQEDIVAEAEADVEIYRVSREREREEARRPRDSVRYERTREDIAAEAEADVEIRRVSRGREREEARRPNELVRYVKTQEDTVAEAEADVEIHRVSREREREEEARRPRDSVRYERTREDIAAEAEADVEIRRASQGREREQEDRRPHKSQRYERTREDIAAEAEADVEIRRVSRGREREEARRPCELVRYVKTQEDIVAEAEADVEIHRVSREREREEEARRPRDSVRYERTREDIVAEAEADVKIRRVSRGREREQEDRRPRESQRYERTWEDIVAEAEAEVEIHRASRGREREEARRPDDSVRYVKTREDIVAEAEADVEIRRVSRGREREQEARRPRESQRYERTREDIVAEAEADVEIRRVSQERERQEEARRPRDSVRYDRTREDIVAEAEADVEIRHVTQKREREQEDRRPRKSQRYERTREDIVAEAEAEVEIRRVSRGREREEARRPNELVRYVKTREDSVAEAEAEVEIRRVSREREREEEARRPRDSVRYERTREDIVAEADLEIRWVSRERKREEEARRPRESQRYERTREDIVAEAEADVEIHRVTREREREEARKPRDSVRYERTREDIVAEAEADVEIRRVSRGREREQEDRRPHESQRYERTREDIVAEADVQIHRVSQKREREQEARRPRESVRYEKTQEDILAEAEADVEIRHVSREREREEARRPRESLRYERTQEDIVTDAEAEVCREEVERADSLHEYEEAVKERRAVRSRAREEAPVRERRLDRQRDLEVERNRFPVRDDQGERQERSLYQTVDVDSRDLVPPGEVPSVTDVRVRYIPSDPDVRPEVQAVPEPCEPQSIAYLIHVIQNLNDPKATTYEIICQQSNDSGQPVYVRKCYVSPQPPVGPCKESSVLEPELQHLPSSSSQENARELEEPRKGEIRERSATGVKEGASAPELDSLKDDTSQAETREDRRDHQSPSVHDVEEKNHQPEGDGPKATEEEVSQEAESQGNKDREAKSRSPAARAPELQEAHKQGQQAAEEPRHPVPQRDEAGCCHEDAELPSPDRSRQAREEENSKRSSQQENNTQPQREEERSPMAPQALSHPMRDEAKAP", "length": 2436, "header": "tr|A0A8V1A5B8-1|A0A8V1AA76_CHICK Computationally mapped isoform of EF-hand domain-containing protein OS=Gallus gallus OX=9031 GN=LOC101751678 PE=4 SV=1 CANONICAL=A0A8V1AA76-1" }, "locus": { "chromosome": "25", "start_pos": 1290141, "end_pos": 1280044, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067200.1", "url": "https://www.ensembl.org/id/ENSGALT00010067200.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041104.1", "url": "https://www.ensembl.org/id/ENSGALP00010041104.1" } ] } }, { "isoform_ac": "A0A8V1AA76-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA76/entry#A0A8V1AA76-1", "sequence": { "sequence": "MSHFLDSVSTIITVFYQHAKEDGDQSKLNRRKMKEFIEKEFADAIVNPHDPQTIEKILQFLEWDGDGEIDFNEFLLLVFRVAKACYWYLQKGQCLLQRTKLITSSKTIQEPEIKNRGSRQQLQEEEPQTLERNRHPPCIPEPQPDTRVQDLETHEETGSHRQQHNTQSRADARQSTRPSEIIPQEYEEQTQEPCDQRSRQRRQPPELDRLGDLQSHKHGSLKAAQNDERQNQEKPQREQLADVRSCSHSCEPQLLPDRRSDRQPREPALPAYDQRNHRPQDQEAVAHGRSSRRPHEPEEADRGRHNQPRNPELLKDERSRNHLRKLEQKELERSSRQPCKPECLDSERLHQSYLQEPLVISHKYNNTRELEEDYYEQGKTQKDRKSCESMMEERTQEDSVAEAEATVKIRRETQKREREEEAKRPRESARYQRTQENTVAEAEADVEIHRVSRGRERELEDRRPHESVRHVKTQENIVAEAEADVEIRRVSREREREQEDRRPRDSERYDRTREDIVAEAEANVEIRRVSRGREREEDRRPDELVRYVKTQEDIVAEAEADVQIPCVSRKREREGKLRRPRESVRYERTREDIAAEAEADVEIRHVTQKRETGQEDRKPRESQRYDKTREDVVAEAEADVEIRRVSRGREREQEDRRPRESQSYERTREDIAAEAEADVEIHRVSRERKREEEARRPRELLRSGQRWEDIVAEAEADVEIHRVSREREREEEARRPRDSVRYERTREDVVAEAEADVEIRRVSRGREREQEDRRPRESQRYERTREDIAAEAEADVEIRRVSQGREREQEDRRPRESQRYERTREDIVAEAEADVEIRRVSRGREREEARRPHQLVRYVKTQEDLVAEAEANVEIHRVSREREREEEARRPRDSVRYERTREDIAAEAEADVEIRRVSRGREREEARRPNELVRYVKTQEDTVAEAEADVEIHHVSREREREEEARRPRDSVRYERTREDIVAEAEADVEIRRVSRGREREQEDRRPRESQRHERTREDIAAEAEANVEIRRVSRERKREEEARRPRDSVRYERTREDTVAEAEADVEIRRVSRGREREEARRPCELVRYVKTQEDIVAEAEADVEIHRVSREREREEEARRPRDSVRYERTREDIAAEAEADVEIRRVSRGREREQEDRRPRESQRYERTREDIVAEAEADVEIRRVSRGREREQDDRRPRESQRYERTREDIVAEAEAEVEIHRVSRGREREEARRPDDSVRYVKTQEDIVAEAEADVEIRRVSREREREEEARRPRDSVRYERTREDIVAEADLEIRRVSRERKREEEARRPRESQRYERTREDIVAEAEADVEIRRVSRGREREEARRPRESVRYVKTQEDIVAEAEADVEIYRVSREREREEARRPRDSVRYDRTREDIAAEAEADVEICRVSRGREREEARRPNELVRYVKTQEDTVAEAEADVEIHRVSREREREEEARRPRDSVRYERTREDIVAEAEADVEIRRVSRGREREQEDRRPRESQRYERTQEDIVAEAEADVEIRRVSRGREREQEDRRPHKSQRYERTREDIAAEAEADVEIRRVSRGREREQEDRRPRESQRYERTREDIVAEAEADVEIRRVSRGREREEARRPRDSVRYERTREDIVAEAEADVEIHRVSREREREEEARRPRDSVRYERTREDIVAEAEADVEIRRVSQGREREQEARRPCESQRYERTREDIVAEAEADVEIRRVSRGREREQDDRRPRESQRYERTREDIVAEAEAEVEIHRASRGREREEARRPDDSVRYVKTREDIVAEAEAEVEIRRVSREREREEEARRPRDSVRYERTQENIVAEAEADVEIRRVSRGREREQEDRRPRESQRYERTREDIVAEAEADVEIRRVSREREREEEARRPRDSVRYERTREDIVAEADLEIRRVSREREREEEARRPRESQRYERTREDIVAEAEADVEIRRVSRGREREEARRPRESVRYVKTQEDIVAEAEADVEIYRVSREREREEARRPRDSVRYERTREDIAAEAEADVEIRRVSRGREREEARRPNELVRYVKTQEDTVAEAEADVEIHRVSREREREEEARRPRDSVRYERTREDIAAEAEADVEIRRASQGREREQEDRRPHKSQRYERTREDIAAEAEADVEIRRVSRGREREEARRPCELVRYVKTQEDIVAEAEADVEIHRVSREREREEEARRPRDSVRYERTREDIVAEAEADVKIRRVSRGREREQEDRRPRESQRYERTWEDIVAEAEAEVEIHRASRGREREEARRPDDSVRYVKTREDIVAEAEADVEIRRVSQGREREQEARRPRESQRYERTREDIVAEAEAEVEIRRVSRGREREEARRPNELVRYVKTREDIVAEAEADVEIRRVSRGREREQEARRPRESQRYERTREDIVAEAEADVEIRRVSQERERQEEARRPRDSVRYDRTREDIVAEAEADVEIRHVTQKREREQEDRRPRKSQRYERTREDIVAEAEAEVEIRRVSRGREREEARRPNELVRYVKTREDSVAEAEAEVEIRRVSREREREEEARRPRDSVRYERTREDIVAEADLEIRWVSRERKREEEARRPRESQRYERTREDIVAEAEADVEIHRVTREREREEARKPRDSVRYERTREDIVAEAEADVEIRRVSRGREREQEDRRPHESQRYERTREDIVAEADVQIHRVSQKREREQEARRPRESVRYEKTQEDILAEAEADVEIRHVSREREREEARRPRESLRYERTQEDIVTDAEAEVCREEVERADSLHEYEEAVKERRAVRSRAREEAPVRERRLDRQRDLEVERNRFPVRDDQGERQERSLYQTVDVDSRDLVPPGEVPSVTDVRVRYIPSDPDVRPEVQAVPEPCEPQSIAYLIHVIQNLNDPKATTYEIICQQSNDSGQPVYVRKCYVSPQPPVGPCKESSVLEPELQHLPSSSSQENARELEEPRKGEIRERSATGVKEGASAPELDSLKDDTSQAETREDRRDHQSPSVHDVEEKNHQPEGDGPKATEEEVSQEAESQGNKDREAKSRSPAARAPELQEAHKQGQQAAEEPRHPVPQRDEAGCCHEDAELPSPDRSRQAREEENSKRSSQQENNTQPQREEERSPMAPQALSHPMRDEAKAP", "length": 3130, "header": "tr|A0A8V1AA76-1|A0A8V1AA76_CHICK Isoform 1 of EF-hand domain-containing protein OS=Gallus gallus OX=9031 GN=LOC101751678 PE=4 SV=1 CANONICAL=A0A8V1AA76-1" }, "locus": { "chromosome": "25", "start_pos": 1290141, "end_pos": 1280044, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067197.1", "url": "https://www.ensembl.org/id/ENSGALT00010067197.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041101.1", "url": "https://www.ensembl.org/id/ENSGALP00010041101.1" } ] } }, { "isoform_ac": "A0A8V1AA88-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA76/entry#A0A8V1AA88-1", "sequence": { "sequence": "MSHFLDSVSTIITVFYQHAKEDGDQSKLNRRKMKEFIEKEFADAIVNPHDPQTIEKILQFLEWDGDGEIDFNEFLLLVFRVAKACYWYLQKGQCLLQRTKLITSSKTIQEPEIKNRGSRQQLQEEEPQTLERNRHPPCIPEPQPDTRVQDLETHEETGSHRQQHNTQSRADARQSTRPSEIIPQEYEEQTQEPCDQRSRQRRQPPELDRLGDLQSHKHGSLKAAQNDERQNQEKPQREQLADVRSCSHSCEPQLLPDRRSDRQPREPALPAYDQRNHRPQDQEAVAHGRSSRRPHEPEEADRGRHNQPRNPELLKDERSRNHLRKLEQKELERSSRQPCKPECLDSERLHQSYLQEPLVISHKYNNTRELEEDYYEQGKTQKDRKSCESMMEERTQEDSVAEAEATVKIRRETQKREREEEAKRPRESARYQRTQENTVAEAEADVEIHRVSRGRERELEDRRPHESVRHVKTQENIVAEAEADVEIRRVSREREREQEDRRPRDSERYDRTREDIVAEAEANVEIRRVSRGREREEDRRPDELVRYVKTQEDIVAEAEADVQIPCVSRKREREGKLRRPRESVRYERTREDIAAEAEADVEIRHVTQKRETGQEDRKPRESQRYDKTREDVVAEAEADVEIRRVSRGREREQEDRRPRESQSYERTREDIAAEAEADVEIHRVSRERKREEEARRPRELLRSGQRWEDIVAEAEADVEIHRVSREREREEEARRPRDSVRYERTREDVVAEAEADVEIRRVSRGREREQEDRRPRESQRYERTREDIAAEAEADVEIRRVSRGREREEARRPNELVRYVKTQEDTVAEAEADVEIHHVSREREREEEARRPRDSVRYERTREDIVAEAEADVEIRRVSRGREREQEDRRPRESQRHERTREDIAAEAEANVEIRRVSRERKREEEARRPRDSVRYERTREDTVAEAEADVEIRRVSRGREREEARRPCELVRYVKTQEDIVAEAEADVEIHRVSREREREEEARRPRDSVRYERTREDIAAEAEADVEIRRVSRGREREQEDRRPRESQRYERTREDIVAEAEADVEIRRVSRGREREQDDRRPRESQRYERTREDIVAEAEAEVEIHRVSRGREREEARRPDDSVRYVKTQEDIVAEAEADVEIRRVSREREREEEARRPRDSVRYERTREDIVAEADLEIRRVSRERKREEEARRPRESQRYERTREDIVAEAEADVEIRRVSRGREREEARRPRESVRYVKTQEDIVAEAEADVEIYRVSREREREEARRPRDSVRYDRTREDIAAEAEADVEICRVSRGREREEARRPNELVRYVKTQEDTVAEAEADVEIHRVSREREREEEARRPRDSVRYERTREDIVAEAEADVEIRRVSRGREREQEDRRPRESQRYERTQEDIVAEAEADVEIRRVSRGREREQEDRRPHKSQRYERTREDIAAEAEADVEIRRVSRGREREQEDRRPRESQRYERTREDIVAEAEADVEIRRVSRGREREEARRPRDSVRYERTREDIVAEAEADVEIRRVSRGREREEARRPRESVRYVKTQEDIVAEAEADVEIYRVSREREREEARRPRDSVRYERTREDIAAEAEADVEIRRVSRGREREEARRPNELVRYVKTQEDTVAEAEADVEIHRVSREREREEEARRPRDSVRYERTREDIVAEAEADVKIRRVSRGREREQEDRRPRESQRYERTWEDIVAEAEAEVEIHRASRGREREEARRPDDSVRYVKTREDSVAEAEAEVEIRRVSREREREEEARRPRDSVRYERTREDIVAEADLEIRWVSRERKREEEARRPRESQRYERTREDIVAEAEADVEIHRVTREREREEARKPRDSVRYERTREDIVAEAEADVEIRRVSRGREREQEDRRPHESQRYERTREDIVAEADVQIHRVSQKREREQEARRPRESVRYEKTQEDILAEAEADVEIRHVSREREREEARRPRESLRYERTQEDIVTDAEAEVCREEVERADSLHEYEEAVKERRAVRSRAREEAPVRERRLDRQRDLEVERNRFPVRDDQGERQERSLYQTVDVDSRDLVPPGEVPSVTDVRVRYIPSDPDVRPEVQAVPEPCEPQSIAYLIHVIQNLNDPKATTYEIICQQSNDSGQPVYVRKCYVSPQPPVGPCKESSVLEPELQHLPSSSSQENARELEEPRKGEIRERSATGVKEGASAPELDSLKDDTSQAETREDRRDHQSPSVHDVEEKNHQPEGDGPKATEEEVSQEAESQGNKDREAKSRSPAARAPELQEAHKQGQQAAEEPRHPVPQRDEAGCCHEDAELPSPDRSRQAREEENSKRSSQQENNTQPQREEERSPMAPQALSHPMRDEAKAP", "length": 2357, "header": "tr|A0A8V1AA88-1|A0A8V1AA88_CHICK Computationally mapped isoform of EF-hand domain-containing protein OS=Gallus gallus OX=9031 GN=LOC101751678 PE=4 SV=1 CANONICAL=A0A8V1AA76-1" }, "locus": { "chromosome": "25", "start_pos": 1290141, "end_pos": 1280044, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067207.1", "url": "https://www.ensembl.org/id/ENSGALT00010067207.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041111.1", "url": "https://www.ensembl.org/id/ENSGALP00010041111.1" } ] } }, { "isoform_ac": "A0A8V1AD08-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA76/entry#A0A8V1AD08-1", "sequence": { "sequence": "MSHFLDSVSTIITVFYQHAKEDGDQSKLNRRKMKEFIEKEFADAIVNPHDPQTIEKILQFLEWDGDGEIDFNEFLLLVFRVAKACYWYLQKGQCLLQRTKLITSSKTIQEPEIKNRGSRQQLQEEEPQTLERNRHPPCIPEPQPDTRVQDLETHEETGSHRQQHNTQSRADARQSTRPSEIIPQEYEEQTQEPCDQRSRQRRQPPELDRLGDLQSHKHGSLKAAQNDERQNQEKPQREQLADVRSCSHSCEPQLLPDRRSDRQPREPALPAYDQRNHRPQDQEAVAHGRSSRRPHEPEEADRGRHNQPRNPELLKDERSRNHLRKLEQKELERSSRQPCKPECLDSERLHQSYLQEPLVISHKYNNTRELEEDYYEQGKTQKDRKSCESMMEERTQEDSVAEAEATVKIRRETQKREREEEAKRPRESARYQRTQENTVAEAEADVEIHRVSRGRERELEDRRPHESVRHVKTQENIVAEAEADVEIRRVSREREREQEDRRPRDSERYDRTREDIVAEAEANVEIRRVSRGREREEDRRPDELVRYVKTQEDIVAEAEADVQIPCVSRKREREGKLRRPRESVRYERTREDIAAEAEADVEIRHVTQKRETGQEDRKPRESQRYDKTREDVVAEAEADVEIRRVSRGREREQEDRRPRESQSYERTREDIAAEAEADVEIHRVSRERKREEEARRPRELLRSGQRWEDIVAEAEADVEIHRVSREREREEEARRPRDSVRYERTREDVVAEAEADVEIRRVSRGREREQEDRRPRESQRYERTREDIAAEAEADVEIRRVSRGREREQEDRRPRESQRYERTQEDIVAEAEADVEIRRVSRGREREQEDRRPHKSQRYERTREDIAAEAEADVEIRRVSRGREREQEDRRPRESQRYERTREDIVAEAEADVEIRRVSRGREREEARRPRDSVRYERTREDIVAEAEADVEIHRVSREREREEEARRPRDSVRYERTREDIVAEAEADVEIRRVSQGREREQEARRPCESQRYERTREDIVAEAEADVEIRRVSRGREREQDDRRPRESQRYERTREDIVAEAEAEVEIHRASRGREREEARRPDDSVRYVKTREDIVAEAEAEVEIRRVSREREREEEARRPRDSVRYERTQENIVAEAEADVEIRRVSRGREREQEDRRPRESQRYERTREDIVAEAEADVEIRRVSREREREEEARRPRDSVRYERTREDIVAEADLEIRRVSREREREEEARRPRESQRYERTREDIVAEAEADVEIRRVSRGREREEARRPRESVRYVKTQEDIVAEAEADVEIYRVSREREREEARRPRDSVRYERTREDIAAEAEADVEIRRVSRGREREEARRPNELVRYVKTQEDTVAEAEADVEIHRVSREREREEEARRPRDSVRYERTREDIAAEAEADVEIRRASQGREREQEDRRPHKSQRYERTREDIAAEAEADVEIRRVSRGREREEARRPCELVRYVKTQEDIVAEAEADVEIHRVSREREREEEARRPRDSVRYERTREDIVAEAEADVKIRRVSRGREREQEDRRPRESQRYERTWEDIVAEAEAEVEIHRASRGREREEARRPDDSVRYVKTREDIVAEAEADVEIRRVSQGREREQEARRPRESQRYERTREDIVAEAEAEVEIRRVSRGREREEARRPNELVRYVKTREDIVAEAEADVEIRRVSRGREREQEARRPRESQRYERTREDIVAEAEADVEIRRVSQERERQEEARRPRDSVRYDRTREDIVAEAEADVEIRHVTQKREREQEDRRPRKSQRYERTREDIVAEAEAEVEIRRVSRGREREEARRPNELVRYVKTREDSVAEAEAEVEIRRVSREREREEEARRPRDSVRYERTREDIVAEADLEIRWVSRERKREEEARRPRESQRYERTREDIVAEAEADVEIHRVTREREREEARKPRDSVRYERTREDIVAEAEADVEIRRVSRGREREQEDRRPHESQRYERTREDIVAEADVQIHRVSQKREREQEARRPRESVRYEKTQEDILAEAEADVEIRHVSREREREEARRPRESLRYERTQEDIVTDAEAEVCREEVERADSLHEYEEAVKERRAVRSRAREEAPVRERRLDRQRDLEVERNRFPVRDDQGERQERSLYQTVDVDSRDLVPPGEVPSVTDVRVRYIPSDPDVRPEVQAVPEPCEPQSIAYLIHVIQNLNDPKATTYEIICQQSNDSGQPVYVRKCYVSPQPPVGPCKESSVLEPELQHLPSSSSQENARELEEPRKGEIRERSATGVKEGASAPELDSLKDDTSQAETREDRRDHQSPSVHDVEEKNHQPEGDGPKATEEEVSQEAESQGNKDREAKSRSPAARAPELQEAHKQGQQAAEEPRHPVPQRDEAGCCHEDAELPSPDRSRQAREEENSKRSSQQENNTQPQREEERSPMAPQALSHPMRDEAKAP", "length": 2437, "header": "tr|A0A8V1AD08-1|A0A8V1AD08_CHICK Computationally mapped isoform of EF-hand domain-containing protein OS=Gallus gallus OX=9031 GN=LOC101751678 PE=4 SV=1 CANONICAL=A0A8V1AA76-1" }, "locus": { "chromosome": "25", "start_pos": 1290141, "end_pos": 1280044, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067209.1", "url": "https://www.ensembl.org/id/ENSGALT00010067209.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041113.1", "url": "https://www.ensembl.org/id/ENSGALP00010041113.1" } ] } }, { "isoform_ac": "A0A8V1AFL2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA76/entry#A0A8V1AFL2-1", "sequence": { "sequence": "MSHFLDSVSTIITVFYQHAKEDGDQSKLNRRKMKEFIEKEFADAIVNPHDPQTIEKILQFLEWDGDGEIDFNEFLLLVFRVAKACYWYLQKGQCLLQRTKLITSSKTIQEPEIKNRGSRQQLQEEEPQTLERNRHPPCIPEPQPDTRVQDLETHEETGSHRQQHNTQSRADARQSTRPSEIIPQEYEEQTQEPCDQRSRQRRQPPELDRLGDLQSHKHGSLKAAQNDERQNQEKPQREQLADVRSCSHSCEPQLLPDRRSDRQPREPALPAYDQRNHRPQDQEAVAHGRSSRRPHEPEEADRGRHNQPRNPELLKDERSRNHLRKLEQKELERSSRQPCKPECLDSERLHQSYLQEPLVISHKYNNTRELEEDYYEQGKTQKDRKSCESMMEERTQEDSVAEAEATVKIRRETQKREREEEAKRPRESARYQRTQENTVAEAEADVEIHRVSRGRERELEDRRPHESVRHVKTQENIVAEAEADVEIRRVSREREREQEDRRPRDSERYDRTREDIVAEAEANVEIRRVSRGREREEDRRPDELVRYVKTQEDIVAEAEADVQIPCVSRKREREGKLRRPRESVRYERTREDIAAEAEADVEIRHVTQKRETGQEDRKPRESQRYDKTREDVVAEAEADVEIRRVSRGREREQEDRRPRESQSYERTREDIAAEAEADVEIHRVSRERKREEEARRPRELLRSGQRWEDIVAEAEADVEIHRVSREREREEEARRPRDSVRYERTREDVVAEAEADVEIRRVSRGREREQEDRRPRESQRYERTREDIAAEAEADVEIRRVSQGREREQEDRRPRESQRYERTREDIVAEAEADVEIRRVSRGREREEARRPHQLVRYVKTQEDLVAEAEANVEIHRVSREREREEEARRPRDSVRYERTREDIAAEAEADVEIRRVSRGREREEARRPNELVRYVKTQEDTVAEAEADVEIHHVSREREREEEARRPRDSVRYERTREDIVAEAEADVEIRRVSRGREREQEDRRPRESQRHERTREDIAAEAEANVEIRRVSRERKREEEARRPRDSVRYERTREDTVAEAEADVEIRRVSRGREREEARRPCELVRYVKTQEDIVAEAEADVEIHRVSREREREEEARRPRDSVRYERTREDIAAEAEADVEIRRVSRGREREQEDRRPRESQRYERTREDIVAEAEADVEIRRVSRGREREQDDRRPRESQRYERTREDIVAEAEAEVEIHRVSRGREREEARRPDDSVRYVKTQEDIVAEAEADVEIRRVSREREREEEARRPRDSVRYERTREDIVAEADLEIRRVSRERKREEEARRPRESQRYERTREDIVAEAEADVEIRRVSRGREREEARRPRESVRYVKTQEDIVAEAEADVEIYRVSREREREEARRPRDSVRYERTREDIAAEAEADVEIRRVSRGREREEARRPNELVRYVKTQEDTVAEAEADVEIHRVSREREREEEARRPRDSVRYERTREDIAAEAEADVEIRRASQGREREQEDRRPHKSQRYERTREDIAAEAEADVEIRRVSRGREREEARRPCELVRYVKTQEDIVAEAEADVEIHRVSREREREEEARRPRDSVRYERTREDIVAEAEADVKIRRVSRGREREQEDRRPRESQRYERTWEDIVAEAEAEVEIHRASRGREREEARRPDDSVRYVKTREDIVAEAEADVEIRRVSQGREREQEARRPRESQRYERTREDIVAEAEAEVEIRRVSRGREREEARRPNELVRYVKTREDIVAEAEADVEIRRVSRGREREQEARRPRESQRYERTREDIVAEAEADVEIRRVSQERERQEEARRPRDSVRYDRTREDIVAEAEADVEIRHVTQKREREQEDRRPRKSQRYERTREDIVAEAEAEVEIRRVSRGREREEARRPNELVRYVKTREDSVAEAEAEVEIRRVSREREREEEARRPRDSVRYERTREDIVAEADLEIRWVSRERKREEEARRPRESQRYERTREDIVAEAEADVEIHRVTREREREEARKPRDSVRYERTREDIVAEAEADVEIRRVSRGREREQEDRRPHESQRYERTREDIVAEADVQIHRVSQKREREQEARRPRESVRYEKTQEDILAEAEADVEIRHVSREREREEARRPRESLRYERTQEDIVTDAEAEVCREEVERADSLHEYEEAVKERRAVRSRAREEAPVRERRLDRQRDLEVERNRFPVRDDQGERQERSLYQTVDVDSRDLVPPGEVPSVTDVRVRYIPSDPDVRPEVQAVPEPCEPQSIAYLIHVIQNLNDPKATTYEIICQQSNDSGQPVYVRKCYVSPQPPVGPCKESSVLEPELQHLPSSSSQENARELEEPRKGEIRERSATGVKEGASAPELDSLKDDTSQAETREDRRDHQSPSVHDVEEKNHQPEGDGPKATEEEVSQEAESQGNKDREAKSRSPAARAPELQEAHKQGQQAAEEPRHPVPQRDEAGCCHEDAELPSPDRSRQAREEENSKRSSQQENNTQPQREEERSPMAPQALSHPMRDEAKAP", "length": 2513, "header": "tr|A0A8V1AFL2-1|A0A8V1AFL2_CHICK Computationally mapped isoform of EF-hand domain-containing protein OS=Gallus gallus OX=9031 GN=LOC101751678 PE=4 SV=1 CANONICAL=A0A8V1AA76-1" }, "locus": { "chromosome": "25", "start_pos": 1290141, "end_pos": 1280044, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067198.1", "url": "https://www.ensembl.org/id/ENSGALT00010067198.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041102.1", "url": "https://www.ensembl.org/id/ENSGALP00010041102.1" } ] } }, { "isoform_ac": "A0A8V1AFL7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA76/entry#A0A8V1AFL7-1", "sequence": { "sequence": "MSHFLDSVSTIITVFYQHAKEDGDQSKLNRRKMKEFIEKEFADAIVNPHDPQTIEKILQFLEWDGDGEIDFNEFLLLVFRVAKACYWYLQKGQCLLQRTKLITSSKTIQEPEIKNRGSRQQLQEEEPQTLERNRHPPCIPEPQPDTRVQDLETHEETGSHRQQHNTQSRADARQSTRPSEIIPQEYEEQTQEPCDQRSRQRRQPPELDRLGDLQSHKHGSLKAAQNDERQNQEKPQREQLADVRSCSHSCEPQLLPDRRSDRQPREPALPAYDQRNHRPQDQEAVAHGRSSRRPHEPEEADRGRHNQPRNPELLKDERSRNHLRKLEQKELERSSRQPCKPECLDSERLHQSYLQEPLVISHKYNNTRELEEDYYEQGKTQKDRKSCESMMEERTQEDSVAEAEATVKIRRETQKREREEEAKRPRESARYQRTQENTVAEAEADVEIHRVSRGRERELEDRRPHESVRHVKTQENIVAEAEADVEIRRVSREREREQEDRRPRDSERYDRTREDIVAEAEANVEIRRVSRGREREEDRRPDELVRYVKTQEDIVAEAEADVQIPCVSRKREREGKLRRPRESVRYERTREDIAAEAEADVEIRHVTQKRETGQEDRKPRESQRYDKTREDVVAEAEADVEIRRVSRGREREQEDRRPRESQSYERTREDIAAEAEADVEIHRVSRERKREEEARRPRELLRSGQRWEDIVAEAEADVEIHRVSREREREEEARRPRDSVRYERTREDVVAEAEADVEIRRVSRGREREQEDRRPRESQRYERTREDIAAEAEADVEIRRVSQGREREQEDRRPRESQRYERTREDIVAEAEADVEIRRVSRGREREEARRPHQLVRYVKTQEDLVAEAEANVEIHRVSREREREEEARRPRDSVRYERTREDIAAEAEADVEIRRVSRGREREEARRPNELVRYVKTQEDTVAEAEADVEIHHVSREREREEEARRPRDSVRYERTREDIVAEAEADVEIRRVSRGREREQEDRRPRESQRHERTREDIAAEAEANVEIRRVSRERKREEEARRPRDSVRYERTREDTVAEAEADVEIRRVSRGREREEARRPCELVRYVKTQEDIVAEAEADVEIHRVSREREREEEARRPRDSVRYERTREDIAAEAEADVEIRRVSRGREREQEDRRPRESQRYERTREDIVAEAEADVEIRRVSRGREREQDDRRPRESQRYERTREDIVAEAEAEVEIHRVSRGREREEARRPDDSVRYVKTREDIVAEAEADVEIRRVSQGREREQEARRPRESQRYERTREDIVAEAEADVEIRRVSQERERQEEARRPRDSVRYDRTREDIVAEAEADVEIRHVTQKREREQEDRRPRKSQRYERTREDIVAEAEAEVEIRRVSRGREREEARRPNELVRYVKTREDSVAEAEAEVEIRRVSREREREEEARRPRDSVRYERTREDIVAEADLEIRWVSRERKREEEARRPRESQRYERTREDIVAEAEADVEIHRVTREREREEARKPRDSVRYERTREDIVAEAEADVEIRRVSRGREREQEDRRPHESQRYERTREDIVAEADVQIHRVSQKREREQEARRPRESVRYEKTQEDILAEAEADVEIRHVSREREREEARRPRESLRYERTQEDIVTDAEAEVCREEVERADSLHEYEEAVKERRAVRSRAREEAPVRERRLDRQRDLEVERNRFPVRDDQGERQERSLYQTVDVDSRDLVPPGEVPSVTDVRVRYIPSDPDVRPEVQAVPEPCEPQSIAYLIHVIQNLNDPKATTYEIICQQSNDSGQPVYVRKCYVSPQPPVGPCKESSVLEPELQHLPSSSSQENARELEEPRKGEIRERSATGVKEGASAPELDSLKDDTSQAETREDRRDHQSPSVHDVEEKNHQPEGDGPKATEEEVSQEAESQGNKDREAKSRSPAARAPELQEAHKQGQQAAEEPRHPVPQRDEAGCCHEDAELPSPDRSRQAREEENSKRSSQQENNTQPQREEERSPMAPQALSHPMRDEAKAP", "length": 2014, "header": "tr|A0A8V1AFL7-1|A0A8V1AFL7_CHICK Computationally mapped isoform of EF-hand domain-containing protein OS=Gallus gallus OX=9031 GN=LOC101751678 PE=4 SV=1 CANONICAL=A0A8V1AA76-1" }, "locus": { "chromosome": "25", "start_pos": 1290141, "end_pos": 1280044, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067203.1", "url": "https://www.ensembl.org/id/ENSGALT00010067203.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041107.1", "url": "https://www.ensembl.org/id/ENSGALP00010041107.1" } ] } }, { "isoform_ac": "A0A8V1AFM3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA76/entry#A0A8V1AFM3-1", "sequence": { "sequence": "MSHFLDSVSTIITVFYQHAKEDGDQSKLNRRKMKEFIEKEFADAIVNPHDPQTIEKILQFLEWDGDGEIDFNEFLLLVFRVAKACYWYLQKGQCLLQRTKLITSSKTIQEPEIKNRGSRQQLQEEEPQTLERNRHPPCIPEPQPDTRVQDLETHEETGSHRQQHNTQSRADARQSTRPSEIIPQEYEEQTQEPCDQRSRQRRQPPELDRLGDLQSHKHGSLKAAQNDERQNQEKPQREQLADVRSCSHSCEPQLLPDRRSDRQPREPALPAYDQRNHRPQDQEAVAHGRSSRRPHEPEEADRGRHNQPRNPELLKDERSRNHLRKLEQKELERSSRQPCKPECLDSERLHQSYLQEPLVISHKYNNTRELEEDYYEQGKTQKDRKSCESMMEERTQEDSVAEAEATVKIRRETQKREREEEAKRPRESARYQRTQENTVAEAEADVEIHRVSRGRERELEDRRPHESVRHVKTQENIVAEAEADVEIRRVSREREREQEDRRPRDSERYDRTREDIVAEAEANVEIRRVSRGREREEDRRPDELVRYVKTQEDIVAEAEADVQIPCVSRKREREGKLRRPRESVRYERTREDIAAEAEADVEIRHVTQKRETGQEDRKPRESQRYDKTREDVVAEAEADVEIRRVSRGREREQEDRRPRESQSYERTREDIAAEAEADVEIHRVSRERKREEEARRPRELLRSGQRWEDIVAEAEADVEIHRVSREREREEEARRPRDSVRYERTREDVVAEAEADVEIRRVSRGREREQEDRRPRESQRYERTREDIVAEAEADVEIRRVSRGREREEARRPCELVRYVKTQEDIVAEAEADVEIHRVSREREREEEARRPRDSVRYERTREDIAAEAEADVEIRRVSRGREREQEDRRPRESQRYERTREDIVAEAEAEVEIHRVSRGREREEARRPDDSVRYVKTQEDIVAEAEADVEIRRVSREREREEEARRPRDSVRYERTREDIVAEAEADVEIRRVSRGREREQEDRRPRESQRYERTQEDIVAEAEADVEIRRVSRGREREQEDRRPHKSQRYERTREDIAAEAEADVEIRRVSRGREREQEDRRPRESQRYERTREDIVAEAEADVEIRRVSRGREREEARRPRDSVRYERTREDIVAEAEADVEIRRVSRGREREEARRPRESVRYVKTQEDIVAEAEADVEIYRVSREREREEARRPRDSVRYERTREDIAAEAEADVEIRRVSRGREREEARRPNELVRYVKTQEDIVAEAEADVEIHRVSREREREEEARRPRDSVRYERTREDIVAEAEADVKIRRVSRGREREQEDRRPRESQRYERTWEDIVAEAEAEVEIHRASRGREREEARRPDDSVRYVKTREDSVAEAEAEVEIRRVSREREREEEARRPRDSVRYERTREDIVAEADLEIRWVSRERKREEEARRPRESQRYERTREDIVAEAEADVEIHRVTREREREEARKPRDSVRYERTREDIVAEAEADVEIRRVSRGREREQEDRRPHESQRYERTREDIVAEADVQIHRVSQKREREQEARRPRESVRYEKTQEDILAEAEADVEIRHVSREREREEARRPRESLRYERTQEDIVTDAEAEVCREEVERADSLHEYEEAVKERRAVRSRAREEAPVRERRLDRQRDLEVERNRFPVRDDQGERQERSLYQTVDVDSRDLVPPGEVPSVTDVRVRYIPSDPDVRPEVQAVPEPCEPQSIAYLIHVIQNLNDPKATTYEIICQQSNDSGQPVYVRKCYVSPQPPVGPCKESSVLEPELQHLPSSSSQENARELEEPRKGEIRERSATGVKEGASAPELDSLKDDTSQAETREDRRDHQSPSVHDVEEKNHQPEGDGPKATEEEVSQEAESQGNKDREAKSRSPAARAPELQEAHKQGQQAAEEPRHPVPQRDEAGCCHEDAELPSPDRSRQAREEENSKRSSQQENNTQPQREEERSPMAPQALSHPMRDEAKAP", "length": 1973, "header": "tr|A0A8V1AFM3-1|A0A8V1AFM3_CHICK Computationally mapped isoform of EF-hand domain-containing protein OS=Gallus gallus OX=9031 GN=LOC101751678 PE=4 SV=1 CANONICAL=A0A8V1AA76-1" }, "locus": { "chromosome": "25", "start_pos": 1290141, "end_pos": 1280044, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067208.1", "url": "https://www.ensembl.org/id/ENSGALT00010067208.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041112.1", "url": "https://www.ensembl.org/id/ENSGALP00010041112.1" } ] } }, { "isoform_ac": "A0A8V1AHI1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA76/entry#A0A8V1AHI1-1", "sequence": { "sequence": "MSHFLDSVSTIITVFYQHAKEDGDQSKLNRRKMKEFIEKEFADAIVNPHDPQTIEKILQFLEWDGDGEIDFNEFLLLVFRVAKACYWYLQKGQCLLQRTKLITSSKTIQEPEIKNRGSRQQLQEEEPQTLERNRHPPCIPEPQPDTRVQDLETHEETGSHRQQHNTQSRADARQSTRPSEIIPQEYEEQTQEPCDQRSRQRRQPPELDRLGDLQSHKHGSLKAAQNDERQNQEKPQREQLADVRSCSHSCEPQLLPDRRSDRQPREPALPAYDQRNHRPQDQEAVAHGRSSRRPHEPEEADRGRHNQPRNPELLKDERSRNHLRKLEQKELERSSRQPCKPECLDSERLHQSYLQEPLVISHKYNNTRELEEDYYEQGKTQKDRKSCESMMEERTQEDSVAEAEATVKIRRETQKREREEEAKRPRESARYQRTQENTVAEAEADVEIHRVSRGRERELEDRRPHESVRHVKTQENIVAEAEADVEIRRVSREREREQEDRRPRDSERYDRTREDIVAEAEANVEIRRVSRGREREEDRRPDELVRYVKTQEDIVAEAEADVQIPCVSRKREREGKLRRPRESVRYERTREDIAAEAEADVEIRHVTQKRETGQEDRKPRESQRYDKTREDVVAEAEADVEIRRVSRGREREQEDRRPRESQSYERTREDIAAEAEADVEIHRVSRERKREEEARRPRELLRSGQRWEDIVAEAEADVEIHRVSREREREEEARRPRDSVRYERTREDVVAEAEADVEIRRVSRGREREQEDRRPRESQRYERTREDIAAEAEADVEIRRVSQGREREQEDRRPRESQRYERTREDIVAEAEADVEIRRVSRGREREEARRPHQLVRYVKTQEDLVAEAEANVEIHRVSREREREEEARRPRDSVRYERTREDIAAEAEADVEIRRVSRGREREEARRPNELVRYVKTQEDTVAEAEADVEIHHVSREREREEEARRPRDSVRYERTREDIVAEAEADVEIRRVSRGREREQEDRRPRESQRHERTREDIAAEAEANVEIRRVSRERKREEEARRPRDSVRYERTREDTVAEAEADVEIRRVSRGREREEARRPCELVRYVKTQEDIVAEAEADVEIRRVSREREREEEARRPRDSVRYERTQENIVAEAEADVEIRRVSRGRKREEEARRPRESQRYERTREDIVAEAEADVEIRRVSQEREREEEARRPRDSVRYERTREDIVAEADLEIRRVSRERKREEEARRPRESQRYERTQEDIVAEAEADVEIRRVSRGREREQEDRRPHKSQRYERTREDIAAEAEADVEIRRVSRGREREQEDRRPRESQRYERTREDIVAEAEADVEIRRVSRGREREEARRPRDSVRYERTREDIAAEAEADVEIRRASQGREREQEDRRPHKSQRYERTREDIAAEAEADVEIRRVSRGREREEARRPCELVRYVKTQEDIVAEAEADVEIHRVSREREREEEARRPRDSVRYERTREDIVAEAEADVKIRRVSRGREREQEDRRPRESQRYERTWEDIVAEAEAEVEIHRASRGREREEARRPDDSVRYVKTREDIVAEAEADVEIRRVSQGREREQEARRPRESQRYERTREDIVAEAEAEVEIRRVSRGREREEARRPNELVRYVKTREDIVAEAEADVEIRRVSRGREREQEARRPRESQRYERTREDIVAEAEADVEIRRVSQERERQEEARRPRDSVRYDRTREDIVAEAEADVEIRHVTQKREREQEDRRPRKSQRYERTREDIVAEAEAEVEIRRVSRGREREEARRPNELVRYVKTREDSVAEAEAEVEIRRVSREREREEEARRPRDSVRYERTREDIVAEADLEIRWVSRERKREEEARRPRESQRYERTREDIVAEAEADVEIHRVTREREREEARKPRDSVRYERTREDIVAEAEADVEIRRVSRGREREQEDRRPHESQRYERTREDIVAEADVQIHRVSQKREREQEARRPRESVRYEKTQEDILAEAEADVEIRHVSREREREEARRPRESLRYERTQEDIVTDAEAEVCREEVERADSLHEYEEAVKERRAVRSRAREEAPVRERRLDRQRDLEVERNRFPVRDDQGERQERSLYQTVDVDSRDLVPPGEVPSVTDVRVRYIPSDPDVRPEVQAVPEPCEPQSIAYLIHVIQNLNDPKATTYEIICQQSNDSGQPVYVRKCYVSPQPPVGPCKESSVLEPELQHLPSSSSQENARELEEPRKGEIRERSATGVKEGASAPELDSLKDDTSQAETREDRRDHQSPSVHDVEEKNHQPEGDGPKATEEEVSQEAESQGNKDREAKSRSPAARAPELQEAHKQGQQAAEEPRHPVPQRDEAGCCHEDAELPSPDRSRQAREEENSKRSSQQENNTQPQREEERSPMAPQALSHPMRDEAKAP", "length": 2399, "header": "tr|A0A8V1AHI1-1|A0A8V1AA76_CHICK Computationally mapped isoform of EF-hand domain-containing protein OS=Gallus gallus OX=9031 GN=LOC101751678 PE=4 SV=1 CANONICAL=A0A8V1AA76-1" }, "locus": { "chromosome": "25", "start_pos": 1290141, "end_pos": 1280044, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067201.1", "url": "https://www.ensembl.org/id/ENSGALT00010067201.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041105.1", "url": "https://www.ensembl.org/id/ENSGALP00010041105.1" } ] } }, { "isoform_ac": "A0A8V1AHI8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA76/entry#A0A8V1AHI8-1", "sequence": { "sequence": "MSHFLDSVSTIITVFYQHAKEDGDQSKLNRRKMKEFIEKEFADAIVNPHDPQTIEKILQFLEWDGDGEIDFNEFLLLVFRVAKACYWYLQKGQCLLQRTKLITSSKTIQEPEIKNRGSRQQLQEEEPQTLERNRHPPCIPEPQPDTRVQDLETHEETGSHRQQHNTQSRADARQSTRPSEIIPQEYEEQTQEPCDQRSRQRRQPPELDRLGDLQSHKHGSLKAAQNDERQNQEKPQREQLADVRSCSHSCEPQLLPDRRSDRQPREPALPAYDQRNHRPQDQEAVAHGRSSRRPHEPEEADRGRHNQPRNPELLKDERSRNHLRKLEQKELERSSRQPCKPECLDSERLHQSYLQEPLVISHKYNNTRELEEDYYEQGKTQKDRKSCESMMEERTQEDSVAEAEATVKIRRETQKREREEEAKRPRESARYQRTQENTVAEAEADVEIHRVSRGRERELEDRRPHESVRHVKTQENIVAEAEADVEIRRVSREREREQEDRRPRDSERYDRTREDIVAEAEANVEIRRVSRGREREEDRRPDELVRYVKTQEDIVAEAEADVQIPCVSRKREREGKLRRPRESVRYERTREDIAAEAEADVEIRHVTQKRETGQEDRKPRESQRYDKTREDVVAEAEADVEIRRVSRGREREQEDRRPRESQSYERTREDIAAEAEADVEIHRVSRERKREEEARRPRELLRSGQRWEDIVAEAEADVEIHRVSREREREEEARRPRDSVRYERTREDVVAEAEADVEIRRVSRGREREQEDRRPRESQRYERTREDIAAEAEADVEIRRVSQGREREQEDRRPRESQRYERTREDIVAEAEADVEIRRVSRGREREEARRPHQLVRYVKTQEDLVAEAEANVEIHRVSREREREEEARRPRDSVRYERTREDIAAEAEADVEIRRVSRGREREEARRPNELVRYVKTQEDTVAEAEADVEIHHVSREREREEEARRPRDSVRYERTREDIVAEAEADVEIRRVSRGREREQEDRRPRESQRHERTREDIAAEAEANVEIRRVSRERKREEEARRPRDSVRYERTREDTVAEAEADVEIRRVSRGREREEARRPCELVRYVKTQEDIVAEAEADVEIHRVSREREREEEARRPRDSVRYERTREDIAAEAEADVEIRRVSRGREREQEDRRPRESQRYERTREDIVAEAEADVEIRRVSRGREREQDDRRPRESQRYERTREDIVAEAEAEVEIHRVSRGREREEARRPDDSVRYVKTREDIVAEAEAEVEIRRVSREREREEEARRPRDSVRYERTQENIVAEAEADVEIRRVSRGREREQEDRRPRESQRYERTREDIVAEAEADVEIRRVSREREREEEARRPRDSVRYERTREDIVAEADLEIRWVSRERKREEEARRPRESQRYERTREDIVAEAEADVEIHRVTREREREEARKPRDSVRYERTREDIVAEAEADVEIRRVSRGREREQEDRRPHESQRYERTREDIVAEADVQIHRVSQKREREQEARRPRESVRYEKTQEDILAEAEADVEIRHVSREREREEARRPRESLRYERTQEDIVTDAEAEVCREEVERADSLHEYEEAVKERRAVRSRAREEAPVRERRLDRQRDLEVERNRFPVRDDQGERQERSLYQTVDVDSRDLVPPGEVPSVTDVRVRYIPSDPDVRPEVQAVPEPCEPQSIAYLIHVIQNLNDPKATTYEIICQQSNDSGQPVYVRKCYVSPQPPVGPCKESSVLEPELQHLPSSSSQENARELEEPRKGEIRERSATGVKEGASAPELDSLKDDTSQAETREDRRDHQSPSVHDVEEKNHQPEGDGPKATEEEVSQEAESQGNKDREAKSRSPAARAPELQEAHKQGQQAAEEPRHPVPQRDEAGCCHEDAELPSPDRSRQAREEENSKRSSQQENNTQPQREEERSPMAPQALSHPMRDEAKAP", "length": 1937, "header": "tr|A0A8V1AHI8-1|A0A8V1AA76_CHICK Computationally mapped isoform of EF-hand domain-containing protein OS=Gallus gallus OX=9031 GN=LOC101751678 PE=4 SV=1 CANONICAL=A0A8V1AA76-1" }, "locus": { "chromosome": "25", "start_pos": 1290141, "end_pos": 1280044, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067206.1", "url": "https://www.ensembl.org/id/ENSGALT00010067206.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041110.1", "url": "https://www.ensembl.org/id/ENSGALP00010041110.1" } ] } }, { "isoform_ac": "A0A8V1AHJ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA76/entry#A0A8V1AHJ2-1", "sequence": { "sequence": "MSHFLDSVSTIITVFYQHAKEDGDQSKLNRRKMKEFIEKEFADAIVNPHDPQTIEKILQFLEWDGDGEIDFNEFLLLVFRVAKACYWYLQKGQCLLQRTKLITSSKTIQEPEIKNRGSRQQLQEEEPQTLERNRHPPCIPEPQPDTRVQDLETHEETGSHRQQHNTQSRADARQSTRPSEIIPQEYEEQTQEPCDQRSRQRRQPPELDRLGDLQSHKHGSLKAAQNDERQNQEKPQREQLADVRSCSHSCEPQLLPDRRSDRQPREPALPAYDQRNHRPQDQEAVAHGRSSRRPHEPEEADRGRHNQPRNPELLKDERSRNHLRKLEQKELERSSRQPCKPECLDSERLHQSYLQEPLVISHKYNNTRELEEDYYEQGKTQKDRKSCESMMEERTQEDSVAEAEATVKIRRETQKREREEEAKRPRESARYQRTQENTVAEAEADVEIHRVSRGRERELEDRRPHESVRHVKTQENIVAEAEADVEIRRVSREREREQEDRRPRDSERYDRTREDIVAEAEANVEIRRVSRGREREEDRRPDELVRYVKTQEDIVAEAEADVEIHRVSREREREEEARRPRDSVRYERTREDIAAEAEADVEIRRVSRGREREQEDRRPRESQRYERTREDIVAEAEADVEIRRVSRGREREQDDRRPRESQRYERTREDIVAEAEAEVEIHRVSRGREREEARRPDDSVRYVKTQEDIVAEAEADVEIRRVSREREREEEARRPRDSVRYERTREDIVAEADLEIRRVSRERKREEEARRPRESQRYERTREDIVAEAEADVEIRRVSRGREREEARRPRESVRYVKTQEDTVAEAEADVEIHRVSREREREEEARRPRDSVRYERTREDIVAEAEADVEIRRVSRGREREQEDRRPRESQRYERTQEDIVAEAEADVEIRRVSRGREREQEDRRPHKSQRYERTREDIAAEAEADVEIRRVSRGREREQEDRRPRESQRYERTREDIVAEAEADVEIRRVSRGREREEARRPRDSVRYERTREDIVAEAEADVEIRRVSRGREREEARRPRESVRYVKTQEDIVAEAEADVEIYRVSREREREEARRPRDSVRYERTREDIAAEAEADVEIRRVSRGREREEARRPNELVRYVKTQEDTVAEAEADVEIHRVSREREREEEARRPRDSVRYERTREDIAAEAEADVEIRRASQGREREQEDRRPHKSQRYERTREDIAAEAEADVEIRRVSRGREREEARRPCELVRYVKTQEDIVAEAEADVEIHRVSREREREEEARRPRDSVRYERTREDIVAEAEADVKIRRVSRGREREQEDRRPRESQRYERTWEDIVAEAEAEVEIHRASRGREREEARRPDDSVRYVKTREDIVAEAEADVEIRRVSQGREREQEARRPRESQRYERTREDIVAEAEAEVEIRRVSRGREREEARRPNELVRYVKTREDIVAEAEADVEIRRVSRGREREQEARRPRESQRYERTREDIVAEAEAEVEIRRVSRGREREEARRPNELVRYVKTREDSVAEAEAEVEIRRVSREREREEEARRPRDSVRYERTREDIVAEADLEIRWVSRERKREEEARRPRESQRYERTREDIVAEAEADVEIHRVTREREREEARKPRDSVRYERTREDIVAEAEADVEIRRVSRGREREQEDRRPHESQRYERTREDIVAEADVQIHRVSQKREREQEARRPRESVRYEKTQEDILAEAEADVEIRHVSREREREEARRPRESLRYERTQEDIVTDAEAEVCREEVERADSLHEYEEAVKERRAVRSRAREEAPVRERRLDRQRDLEVERNRFPVRDDQGERQERSLYQTVDVDSRDLVPPGEVPSVTDVRVRYIPSDPDVRPEVQAVPEPCEPQSIAYLIHVIQNLNDPKATTYEIICQQSNDSGQPVYVRKCYVSPQPPVGPCKESSVLEPELQHLPSSSSQENARELEEPRKGEIRERSATGVKEGASAPELDSLKDDTSQAETREDRRDHQSPSVHDVEEKNHQPEGDGPKATEEEVSQEAESQGNKDREAKSRSPAARAPELQEAHKQGQQAAEEPRHPVPQRDEAGCCHEDAELPSPDRSRQAREEENSKRSSQQENNTQPQREEERSPMAPQALSHPMRDEAKAP", "length": 2124, "header": "tr|A0A8V1AHJ2-1|A0A8V1AA76_CHICK Computationally mapped isoform of EF-hand domain-containing protein OS=Gallus gallus OX=9031 GN=LOC101751678 PE=4 SV=1 CANONICAL=A0A8V1AA76-1" }, "locus": { "chromosome": "25", "start_pos": 1290141, "end_pos": 1280044, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067211.1", "url": "https://www.ensembl.org/id/ENSGALT00010067211.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041115.1", "url": "https://www.ensembl.org/id/ENSGALP00010041115.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "transition metal ion binding", "id": "GO:0046914", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046914", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AA76", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA76" } ], "pmid": "" }, { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AA76", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA76" } ], "pmid": "" }, { "name": "calcium-dependent protein binding", "id": "GO:0048306", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048306", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AA76", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA76" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction", "id": "GO:0051896", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051896", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AA76", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA76" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 2901, "end_pos": 2903, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3101, "end_pos": 3103, "annotation": "n_glycosylation_sequon" }, { "start_pos": 365, "end_pos": 367, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AA76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA76" }, { "id": "PS50222", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50222" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EF-hand", "eco_id": "ECO_0000259", "start_pos": 49, "end_pos": 84, "start_aa": "His", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 2901, "end_pos": 2903 }, { "start_pos": 3101, "end_pos": 3103 }, { "start_pos": 365, "end_pos": 367 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AA83-1", "uniprot_ac": "A0A8V1AA83", "uniprot_id": "A0A8V1AA83_CHICK", "mass": { "chemical_mass": 60075.0, "monoisotopic_mass": 60075.0 }, "refseq": {}, "gene_names": [ { "name": "TTLL11", "type": "recommended", "evidence": [ { "id": "A0A8V1AA83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA83" } ] } ], "protein_names": [ { "name": "Tubulin tyrosine ligase like 11", "type": "synonym", "evidence": [ { "id": "A0A8V1AA83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA83/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AA83", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA83" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TTLL11", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA83", "locus": { "chromosome": "17", "start_pos": 9216526, "end_pos": 9268062, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027724", "url": "https://www.ensembl.org/id/ENSGALG00010027724" } ] } } ], "crossref": [ { "id": "A0A8V1AA83", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AA83", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR004344", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004344", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A5C3", "url": "https://www.orthodb.org/?gene=A0A8V1A5C3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AA83", "url": "https://www.orthodb.org/?gene=A0A8V1AA83", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12241", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12241", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12241:SF154", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12241:SF154", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03133", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03133", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF27858", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27858", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1A5C3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5C3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A5C3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5C3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AA83", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA83", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AA83-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA83-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTEMVRKVTLSRAVRTMQDLFPVEYNFYPRSWILPEEFPLFVTEVRMMKESDPSWKPTFIVKPDGGCQGDGIYLIKDPNDVRLAGSLQSRPAVVQEYICKPLLVDKLKFDIRLYVLLKSLEPLEIYIAKDGLSRFCTEPYQEPTLKNLHQVFMHLTNYSLNIHSGNFIHSDNANTGSKRTFSSILCRLSSRGADVKKVWSDIISLVIKTIIALTPELKVYYQSDIPAGKPGPTCFQILGFDILLMKNLKPMLLEVNANPSMRIEHEQELSPGVFENVPSPVDEEVKVAVIRDTLRLVDPQKKKRKDIQSQTSEHVSETKEDLLDAGPAGGLEYDTSKTTEAGLPSLCLKQVFPKYAKQFNYLRLVDRVAALFIRFLGVKGTTKLGPTGFRTFIRNCKLSNSNFSMAAVDILYIDITRRWNSMGIDHKESGMCLQAFVEAFFCLAQKKYKSLPLHEQVASLIDFCEYHLAALDEKRLLCGRGVVERRSAVVACPTDGLEGTPALHAPLLNCTAAAGKLAGCRSHRYPGAVSPGAGRD", "length": 536, "header": "tr|A0A8V1AA83-1|A0A8V1AA83_CHICK Isoform 1 of Tubulin tyrosine ligase like 11 OS=Gallus gallus OX=9031 GN=TTLL11 PE=4 SV=1 CANONICAL=A0A8V1AA83-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A5C3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA83/entry#A0A8V1A5C3-1", "sequence": { "sequence": "MEPAGAPPPSCAPAREAEEPPGSPALPAERPRDGEPARKAREEAASAERSHGRGPAGRAARGGGRHGPEERGARTGRRPRVTVDSSKAKTSLEALKISLRQLRWREFPFGRRLPCDIYWHGVSFHDSYIFSGQVNKFPGMTEMVRKVTLSRAVRTMQDLFPVEYNFYPRSWILPEEFPLFVTEILGFDILLMKNLKPMLLEVNANPSMRIEHEQELSPGVFENVPSPVDEEVKVAVIRDTLRLVDPQKKKRKDIQSQTSEHVSETKEDLLDAGPAGGLEYDTSKTTEAGLPSLCLKQVFPKYAKQFNYLRLVDRVAALFIRFLGVKGTTKLGPTGFRTFIRNCKLSNSNFSMAAVDILYIDITRRWNSMGIDHKESGMCLQAFVEAFFCLAQKKYKSLPLHEQVASLIDFCEYHLAALDEKRLLCGRGVVERRSAVVACPTDGLEGTPALHAPLLNCTAAAGKLAGCRSHRYPGAVSPGAGRD", "length": 483, "header": "tr|A0A8V1A5C3-1|A0A8V1AA83_CHICK Computationally mapped isoform of Tubulin tyrosine ligase like 11 OS=Gallus gallus OX=9031 GN=TTLL11 PE=4 SV=1 CANONICAL=A0A8V1AA83-1" }, "locus": { "chromosome": "17", "start_pos": 9268002, "end_pos": 9234592, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067205.1", "url": "https://www.ensembl.org/id/ENSGALT00010067205.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041109.1", "url": "https://www.ensembl.org/id/ENSGALP00010041109.1" } ] } }, { "isoform_ac": "A0A8V1AA83-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA83/entry#A0A8V1AA83-1", "sequence": { "sequence": "MTEMVRKVTLSRAVRTMQDLFPVEYNFYPRSWILPEEFPLFVTEVRMMKESDPSWKPTFIVKPDGGCQGDGIYLIKDPNDVRLAGSLQSRPAVVQEYICKPLLVDKLKFDIRLYVLLKSLEPLEIYIAKDGLSRFCTEPYQEPTLKNLHQVFMHLTNYSLNIHSGNFIHSDNANTGSKRTFSSILCRLSSRGADVKKVWSDIISLVIKTIIALTPELKVYYQSDIPAGKPGPTCFQILGFDILLMKNLKPMLLEVNANPSMRIEHEQELSPGVFENVPSPVDEEVKVAVIRDTLRLVDPQKKKRKDIQSQTSEHVSETKEDLLDAGPAGGLEYDTSKTTEAGLPSLCLKQVFPKYAKQFNYLRLVDRVAALFIRFLGVKGTTKLGPTGFRTFIRNCKLSNSNFSMAAVDILYIDITRRWNSMGIDHKESGMCLQAFVEAFFCLAQKKYKSLPLHEQVASLIDFCEYHLAALDEKRLLCGRGVVERRSAVVACPTDGLEGTPALHAPLLNCTAAAGKLAGCRSHRYPGAVSPGAGRD", "length": 536, "header": "tr|A0A8V1AA83-1|A0A8V1AA83_CHICK Isoform 1 of Tubulin tyrosine ligase like 11 OS=Gallus gallus OX=9031 GN=TTLL11 PE=4 SV=1 CANONICAL=A0A8V1AA83-1" }, "locus": { "chromosome": "17", "start_pos": 9261541, "end_pos": 9234592, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067202.1", "url": "https://www.ensembl.org/id/ENSGALT00010067202.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041106.1", "url": "https://www.ensembl.org/id/ENSGALP00010041106.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AA83", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA83" } ], "pmid": "" }, { "name": "ligase activity", "id": "GO:0016874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016874", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AA83", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA83" } ], "pmid": "" }, { "name": "tubulin-glutamic acid ligase activity", "id": "GO:0070740", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070740", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AA83", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA83" } ], "pmid": "" }, { "name": "tubulin binding", "id": "GO:0015631", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015631", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AA83", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA83" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "microtubule cytoskeleton organization", "id": "GO:0000226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000226", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AA83", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA83" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "ciliary basal body", "id": "GO:0036064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036064", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AA83", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA83" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 157, "end_pos": 159, "annotation": "n_glycosylation_sequon" }, { "start_pos": 402, "end_pos": 404, "annotation": "n_glycosylation_sequon" }, { "start_pos": 509, "end_pos": 511, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 157, "end_pos": 159 }, { "start_pos": 402, "end_pos": 404 }, { "start_pos": 509, "end_pos": 511 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AAK8-1", "uniprot_ac": "A0A8V1AAK8", "uniprot_id": "A0A8V1AAK8_CHICK", "mass": { "chemical_mass": 111715.0, "monoisotopic_mass": 111715.0 }, "refseq": { "ac": "XP_040508596", "name": "DENN domain-containing protein 2C isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040508596" }, "gene_names": [ { "name": "DENND2C", "type": "recommended", "evidence": [ { "id": "A0A8V1AAK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAK8" } ] }, { "name": "DENND2C", "type": "synonym", "evidence": [ { "id": "XP_040508596", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040508596" } ] } ], "protein_names": [ { "name": "DENN domain containing 2C", "type": "synonym", "evidence": [ { "id": "A0A8V1AAK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAK8/entry#names_and_taxonomy" } ] }, { "name": "DENN domain-containing protein 2C isoform X1", "type": "synonym", "evidence": [ { "id": "XP_040508596", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040508596" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052557.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040508596", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040508596" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAK8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAK8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "DENND2C", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAK8", "locus": { "chromosome": "26", "start_pos": 3913177, "end_pos": 3932671, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010025485", "url": "https://www.ensembl.org/id/ENSGALG00010025485" } ] } } ], "crossref": [ { "id": "A0A8V1AAK8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AAK8", "database": "AlphaFoldDB", "categories": [] }, { "id": "100858235", "url": "https://www.ncbi.nlm.nih.gov/gene/100858235", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001194", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001194", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005112", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005112", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005113", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005113", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037516", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037516", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043153", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043153", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051942", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051942", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:100858235", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100858235", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PLPMWRT", "url": "https://omabrowser.org/oma/group/PLPMWRT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A5F8", "url": "https://www.orthodb.org/?gene=A0A8V1A5F8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A5G8", "url": "https://www.orthodb.org/?gene=A0A8V1A5G8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AAK8", "url": "https://www.orthodb.org/?gene=A0A8V1AAK8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15288", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15288", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15288:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15288:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02141", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02141", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03455", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03455", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03456", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03456", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-8876198", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8876198", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_040508596", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040508596", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1A5F8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5F8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A5F8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5F8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A5G8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5G8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A5G8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5G8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AAK8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAK8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AAK8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAK8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPAVQRDKVALAGSSCRTQGLLDAPGCFGVSCQLDACKTQVKLGKTGDGVFLSTLALAMHPAETGDSSFSRSAVQTLSRSHCRNIKQKISQWEGRTQGCSSKEKQQLNDFGVKYDPGCDVPSKVKPEDIEKGRKAGSEDPKNLGLDFRENAGSCLQTTDCGDLKSCACSHASQAKENGKWQPGFPDPGKALPPGNFYTLQGLWRKVDPSTALPVPVDLQKKWGHCGFTEREWKAKGVELFCGAERNVKNSYLEAVEQEEKLAAVPPPKPRRTFRYLAENCASSCSDASATKEAPLEKKRGGDLVSFSNNLEKRTVSRMIRGRIQRKSFEFEDIQGFRNWMSATRSHKLQEETNGTAGPRLIYTQSEDNIYEDIICPAKENPYEDIRVLPLPLWKVPSVWKLPPSQSTSRAPKLPPKPSFLSRKTFELKPSLTSLQGKMVKDTTLPVTLTDWKLFRAVEATSRRKNLPWMVLKIQEIFVSKRGKKRVKLLSPAGREVPPTKGETSGNESDTENQPKSRHKGLLLVQSASKRNPHYQTLERDLIELQEQQLFELFVVVSLQKKSSEIKYTPQIIQQFPSKPEHRFRQSKDTEERLKVIPKFCFPDPKDWFPASDLKSETFSFVLTGEDGSRWFGYCKKLLPEGKGKRLPEVYCIVSRLGCFNLFSKILDEVEKRREMSPALVHPFMRSVMEAPFPAPGRTITVKSFLPGAGNEVMKLCRPSDSRLEHVDFECLFKCLSVSHMIRVFASLLLERRVIFVADNLSTLSKCGHAAVAILYPFTWQHTYIPVLPTSMIDIVCSPTPFLIGILSCSLPQLQDLPLEEVLIVDLCADKFLQEVSDEEEILPHKLQAALVQILEERNEILSHEQSRMQGDMPLNSLVSEAFVHFFVEIVGHYSLHMNVTEKGERVFQREPFRKSHMSRNVRHFLHFFMETQMFAGFIQDRELSKSAVKGLFEVRALEYLESIPETEPTGMNRILRTLGSKMKFLQKK", "length": 988, "header": "tr|A0A8V1AAK8-1|A0A8V1AAK8_CHICK Isoform 1 of DENN domain containing 2C OS=Gallus gallus OX=9031 GN=DENND2C PE=4 SV=1 CANONICAL=A0A8V1AAK8-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A5F8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAK8/entry#A0A8V1A5F8-1", "sequence": { "sequence": "MHPAETGDSSFSRSAVQTLSRSHCRNIKQKISQWEGRTQGCSSKEKQQLNDFGVKYDPGCDVPSKVKPEDIEKGRKAGSEDPKNLGLDFRENAGSCLQTTDCGDLKSCACSHASQAKENGKWQPGFPDPGKALPPGNFYTLQGLWRKVDPSTALPVPVDLQKKWGHCGFTEREWKAKGVELFCGAERNVKNSYLEAVEQEEKLAAVPPPKPRRTFRYLAENCASSCSDASATKEAPLEKKRGGDLVSFSNNLEKRTVSRMIRGRIQRKSFEFEDIQGFRNWMSATRSHKLQEETNGTAGPRLIYTQSEDNIYEDIICPAKENPYEDIRVLPLPLWKVPSVWKLPPSQSTSRAPKMVLKIQEIFVSKRGKKRVKLLSPAGREVPPTKGETSGNESDTENQPKSRHKGLLLVQSASKRNPHYQTLERDLIELQEQQLFELFVVVSLQKKSSEIKYTPQIIQQFPSKPEHRFRQSKDTEERLKVIPKFCFPDPKDWFPASDLKSETFSFVLTGEDGSRWFGYCKKLLPEGKGKRLPEVYCIVSRLGCFNLFSKILDEVEKRREMSPALVHPFMRSVMEAPFPAPGRTITVKSFLPGAGNEVMKLCRPSDSRLEHVDFECLFKCLSVSHMIRVFASLLLERRVIFVADNLSTLSKCGHAAVAILYPFTWQHTYIPVLPTSMIDIVCSPTPFLIGILSCSLPQLQDLPLEEVLIVDLCADKFLQEVSDEEEILPHKLQAALVQILEERNEILSHEQSRDMPLNSLVSEAFVHFFVEIVGHYSLHMNVTEKGERVFQREPFRKSHMSRNVRHFLHFFMETQMFAGFIQDRELSKSAVKGLFEVRALEYLESIPETEPTGMNRILRTLGSKMKFLQKK", "length": 871, "header": "tr|A0A8V1A5F8-1|A0A8V1AAK8_CHICK Computationally mapped isoform of DENN domain containing 2C OS=Gallus gallus OX=9031 GN=DENND2C PE=4 SV=1 CANONICAL=A0A8V1AAK8-1" }, "locus": { "chromosome": "26", "start_pos": 3927723, "end_pos": 3913499, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010062202.1", "url": "https://www.ensembl.org/id/ENSGALT00010062202.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038445.1", "url": "https://www.ensembl.org/id/ENSGALP00010038445.1" } ] } }, { "isoform_ac": "A0A8V1A5G8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAK8/entry#A0A8V1A5G8-1", "sequence": { "sequence": "MHPAETGDSSFSRSAVQTLSRSHCRNIKQKISQWEGRTQGCSSKEKQQLNDFGVKYDPGCDVPSKVKPEDIEKGRKAGSEDPKNLGLDFRENAGSCLQTTDCGDLKSCACSHASQAKENGKWQPGFPDPGKALPPGNFYTLQGLWRKVDPSTALPVPVDLQKKWGHCGFTEREWKAKGVELFCGAERNVKNSYLEAVEQEEKLAAVPPPKPRRTFRYLAENCASSCSDASATKEAPLEKKRGGDLVSFSNNLEKRTVSRMIRGRIQRKSFEFEDIQGFRNWMSATRSHKLQEETNGTAGPRLIYTQSEDNIYEDIICPAKENPYEDIRVLPLPLWKVPSVWKLPPSQSTSRAPKLPPKPSFLSRKTFELKPSLTSLQGKMVKDTTLPVTLTDWKLFRAVEATSRRKNLPWMVLKIQEIFVSKRGKKRVKLLSPAGREVPPTKGETSGNESDTENQPKSRHKGLLLVQSASKRNPHYQTLERDLIELQEQQLFELFVVVSLQKKSSEIKYTPQIIQQFPSKPEHRFRQSKDTEERLKVIPKFCFPDPKDWFPASDLKSETFSFVLTGEDGSRWFGYCKKLLPEGKGKRLPEVYCIVSRLGCFNLFSKILDEVEKRREMSPALVHPFMRSVMEAPFPAPGRTITVKSFLPGAGNEVMKLCRPSDSRLEHVDFECLFKCLSVSHMIRVFASLLLERRVIFVADNLSTLSKCGHAAVAILYPFTWQHTYIPVLPTSMIDIVCSPTPFLIGILSCSLPQLQDLPLEEVLIVDLCADKFLQEVSDEEEILPHKLQAALVQILEERNEILSHEQSRMQGDMPLNSLVSEAFVHFFVEIVGHYSLHMNVTEKGERVFQREPFRKSHMSRNVRHFLHFFMETQMFAGFIQDRELSKSAVKGLFEVRALEYLESIPETEPTGMNRILRTLGSKMKFLQKK", "length": 930, "header": "tr|A0A8V1A5G8-1|A0A8V1AAK8_CHICK Computationally mapped isoform of DENN domain containing 2C OS=Gallus gallus OX=9031 GN=DENND2C PE=4 SV=1 CANONICAL=A0A8V1AAK8-1" }, "locus": { "chromosome": "26", "start_pos": 3927723, "end_pos": 3913499, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010062214.1", "url": "https://www.ensembl.org/id/ENSGALT00010062214.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038455.1", "url": "https://www.ensembl.org/id/ENSGALP00010038455.1" } ] } }, { "isoform_ac": "A0A8V1AAK8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAK8/entry#A0A8V1AAK8-1", "sequence": { "sequence": "MPAVQRDKVALAGSSCRTQGLLDAPGCFGVSCQLDACKTQVKLGKTGDGVFLSTLALAMHPAETGDSSFSRSAVQTLSRSHCRNIKQKISQWEGRTQGCSSKEKQQLNDFGVKYDPGCDVPSKVKPEDIEKGRKAGSEDPKNLGLDFRENAGSCLQTTDCGDLKSCACSHASQAKENGKWQPGFPDPGKALPPGNFYTLQGLWRKVDPSTALPVPVDLQKKWGHCGFTEREWKAKGVELFCGAERNVKNSYLEAVEQEEKLAAVPPPKPRRTFRYLAENCASSCSDASATKEAPLEKKRGGDLVSFSNNLEKRTVSRMIRGRIQRKSFEFEDIQGFRNWMSATRSHKLQEETNGTAGPRLIYTQSEDNIYEDIICPAKENPYEDIRVLPLPLWKVPSVWKLPPSQSTSRAPKLPPKPSFLSRKTFELKPSLTSLQGKMVKDTTLPVTLTDWKLFRAVEATSRRKNLPWMVLKIQEIFVSKRGKKRVKLLSPAGREVPPTKGETSGNESDTENQPKSRHKGLLLVQSASKRNPHYQTLERDLIELQEQQLFELFVVVSLQKKSSEIKYTPQIIQQFPSKPEHRFRQSKDTEERLKVIPKFCFPDPKDWFPASDLKSETFSFVLTGEDGSRWFGYCKKLLPEGKGKRLPEVYCIVSRLGCFNLFSKILDEVEKRREMSPALVHPFMRSVMEAPFPAPGRTITVKSFLPGAGNEVMKLCRPSDSRLEHVDFECLFKCLSVSHMIRVFASLLLERRVIFVADNLSTLSKCGHAAVAILYPFTWQHTYIPVLPTSMIDIVCSPTPFLIGILSCSLPQLQDLPLEEVLIVDLCADKFLQEVSDEEEILPHKLQAALVQILEERNEILSHEQSRMQGDMPLNSLVSEAFVHFFVEIVGHYSLHMNVTEKGERVFQREPFRKSHMSRNVRHFLHFFMETQMFAGFIQDRELSKSAVKGLFEVRALEYLESIPETEPTGMNRILRTLGSKMKFLQKK", "length": 988, "header": "tr|A0A8V1AAK8-1|A0A8V1AAK8_CHICK Isoform 1 of DENN domain containing 2C OS=Gallus gallus OX=9031 GN=DENND2C PE=4 SV=1 CANONICAL=A0A8V1AAK8-1" }, "locus": { "chromosome": "26", "start_pos": 3931026, "end_pos": 3913499, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010062211.1", "url": "https://www.ensembl.org/id/ENSGALT00010062211.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038452.1", "url": "https://www.ensembl.org/id/ENSGALP00010038452.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:100858235", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100858235", "resource": "KEGG Pathway" }, { "id": "R-GGA-8876198", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8876198", "resource": "Reactome", "description": "RAB GEFs exchange GTP for GDP on RABs" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZX30-1", "protein_name": "DENN domain containing 2C", "gene_name": "Dennd2c", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MHPTGTMDVGFTRSAVQTLSRSHCKNIKQKISQWEGRANGVTQPAKFHPKDFGVRYNNCHQERPPHKHPTGEERNGGLPRNTDARSHDQSEGESESRELKDPHPLEGEPNSSRMCARVKQIESCQAVAVDPEASLPPGNFYTSQIPWKSIEGLTPNKVFTVALSPCDFTEEEPELSVLDSSYRVAKSLENIYCEPEGQECGPSINPLPKPRRTFRYLSESDGMPYKERNCDQKNCESVCCADSSLASFQDPEPKRYGGKIRGRSKRKSFEFEDIQHFRNSRKIHEELERNAGSALYYTQSEDNIYEDIIYPAKENPYEDIPVQSFPIWRSPSAWRLPPAKSAFRTPKLPPKPQFLQRKTMELKNTQAYLRSKLTKDTTLPVTLTEWKLFRAGEVANRKKRNLPRLVLKINDTFESKRGKKRVKLQPYTGKEAPSSKGETSGNESDAEYLPKNRHKRLAQLQQSSKRSPHYQTLERDLIELQEQQLFELFVVVSLQKKASGMEYMPRVIQQFPSKGDHGYKQSKDTEERLKVIPRFCFPDSEDCAPTLELKSETFSFVLTGEDGSRWFGYCKKLLPEGRGKRLPEVYCMVSRLGCFNLFSKILDEVEKRREMSPALVYPFMRSVMEAPFPAPGRTITVKSYLPGAGDESIELCRPLDSRLEHVDFECLFKCLSVRHLIRVCASLLLERRVIFVADSLSTLSKCGHAVVATLYPFTWQHTYIPVLPVSMIDIVCSPTPFFIGILSCSLPLLQDLPIEEVLIVDLCADKFLQEVSDEDEIMPPKLQAALVQILEERDEVLAQERQFSQDVTLNSLVSEAFVRFFVELVGHYSLNMTVTERGERVFLREPFRKSHTSRSVRHFLDLFMETQMFAGFVQDRELRQSGVKGLFEVRALQYLETIPESEPSGVNRILRSLGSKMRFLHKK", "length": 923 }, "evidence": [ { "id": "A0A8V1AAK8", "url": "https://omabrowser.org/oma/group/A0A8V1AAK8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1R7P0-1", "protein_name": "DENN domain-containing protein 2C isoform X1", "gene_name": "dennd2c", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLALGVDHEKKGGPGGKTREPGVNIKQKISQWEGLTQQEDIRSGKVQTQRTLASRRLSEDLLGNGLDSSDGGRNKATVFKAKSLGLDFRENLKTFKPVTPEVKPNFPRNRDHLNKCVTPSTVSQVQVAKPNVKINNINSSHFSNVEITSLPQCVDYPEPSLPPGNFYTSRGFWKRLEADESFWEREKDSSLMTKGLDFGPSSPPPKPQRTFQYKGASSPTNQWIQPENQTPAVSKLNQVQKHDIILKPPSCPPPPCPVNTVNGFSRHRKNRKSFEFEDVVRLSAQTASRGKESRRSGLYHALSEDSIYEDIISDMPKENPYEDITLSPMCLPIRRQRNYTVGQRERPQLKLSPKPFTLLPNGDRLHKVGRDHRQLTTSPTCSTISSSPRSSAVKPAALYKTSRQPLLVNRIQEIFESKRGRKRVWATATREELSGTESDPEENSKDRSHRTVYVQSTLKRRPGYRTLERDLIQLQQQQLFQQFVVVSLRKGSPGNTYIPEITQQFPTKFEKSSRLSREAEDRLRAIPKFCFPDCHDWRPSSDHTSETFSFVLTGEDGSRLFGYCRKILPSGKGKRLPEVHCIVSRLGCFNLFSKILEEVERRREISPALVSPFMHSVMEAPFPAPGRTITVKSFLPGSGNEVLTLCRPVDSRLEHVDFESLLQCLSVSRLLQVFASLMLERRVIFIADKLSVLSRCAHSALALLYPFTWQHTFVPVLPAGMLDICCSPTPFVMGALSPSLPEVLDMPIEEVLIVDLCTDKFVVQLGDEDCILPSKLQAALQEILENREEILEQNRRDRRGDKSDLSTLVSEAFVWFFVEIVGHYSLYMNDSGPGGTRELQRDAFRKSHPSRGVRQLLQLFMDTQMFAGFIQDRELRKGGVKGLFELRAAEYLDSYPEPETSGVNRFLKGLGNKMKFLQKK", "length": 920 }, "evidence": [ { "id": "A0A8V1AAK8", "url": "https://omabrowser.org/oma/group/A0A8V1AAK8/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAK8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAK8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAK8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAK8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 353, "end_pos": 355, "annotation": "n_glycosylation_sequon" }, { "start_pos": 506, "end_pos": 508, "annotation": "n_glycosylation_sequon" }, { "start_pos": 759, "end_pos": 761, "annotation": "n_glycosylation_sequon" }, { "start_pos": 898, "end_pos": 900, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AAK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAK8" }, { "id": "PS50211", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50211" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "UDENN", "eco_id": "ECO_0000259", "start_pos": 551, "end_pos": 948, "start_aa": "Glu", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 353, "end_pos": 355 }, { "start_pos": 506, "end_pos": 508 }, { "start_pos": 759, "end_pos": 761 }, { "start_pos": 898, "end_pos": 900 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A8N5-1", "uniprot_ac": "A0A8V1A8N5", "uniprot_id": "A0A8V1A8N5_CHICK", "mass": { "chemical_mass": 49863.0, "monoisotopic_mass": 49863.0 }, "refseq": {}, "gene_names": [ { "name": "C1orf228", "type": "recommended", "evidence": [ { "id": "A0A8V1A8N5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8N5" } ] } ], "protein_names": [ { "name": "Armadillo like helical domain containing 1", "type": "synonym", "evidence": [ { "id": "A0A8V1A8N5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8N5/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A8N5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8N5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "C1orf228", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8N5", "locus": {} } ], "crossref": [ { "id": "A0A8V1A8N5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A8N5", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041090", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041090", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR34258", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR34258", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR34258:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR34258:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF17741", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17741", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1A635", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A635", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A635-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A635-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A8N5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8N5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A8N5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8N5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AB64", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB64", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AB64-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB64-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTSVKEQEAIKKLMVFLQEWDSAHRVARNHILDNFIRSNIGKTEPELELEFSQGASLFLARLAAWLRVTYMYSTCINKLLKSIGIFLSAASGRRYIIEFLEMGGVLMLLEILGLNHLNEEDKRESVKLLQLIADAGRKYKELICESYGVQSLAELLATCSSAEVRDEVQILLDSLGRGNPKYQNQVYSGLLAVLPCGSPHAQQLALQTLRSMQDLLEEPPPAGVAPLLAALGTTHPEVQYEAVQLLLAVASRRAPPALLPGLVALLTPPGRKARAKDPMLPPREPTLAHVQQAAAAKAIGVLAKESAEVAEELIQLKVVHGLMVAVGNLDYPLSQRNASISLEYFVRMYPFVEEHVRKAVGDTLFQLFKDCPETWYTKIDPVQAEELASNPVDSPKDMAKMQSAEAGCPLTDLSGDNHYFATSFFLPIHKIYGEFRAFEEDQHALVQNNF", "length": 450, "header": "tr|A0A8V1A8N5-1|A0A8V1A8N5_CHICK Isoform 1 of Armadillo like helical domain containing 1 OS=Gallus gallus OX=9031 GN=C1orf228 PE=4 SV=1 CANONICAL=A0A8V1A8N5-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A635-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8N5/entry#A0A8V1A635-1", "sequence": { "sequence": "MMAEEIMTSVKEQEAIKKLMVFLQEWDSAHRVARNHILDNFIRSNIGKTEPELELEFSQGASLFLARLAAWLRVTYMYSTCINKLLKSIGIFLSAASGRRYIIEFLEMGGVLMLLEILGLNHLNEEDKRESVKLLQLIADAGRKYKELICESYGVQSLAELLATCSSAEVRDEVQILLDSLGRGNPKYQNQVYSGLLAVLPCGSPHAQQLALQTLRSMQDLLEEPPPAGVAPLLAALGTTHPEVQYEAVQLLLAVASRRAPPALLPGLVALLTPPGRKARAKDPMLPPREPTLAHVQQAAAAKAIGVLAKESAEVAEELIQLKVVHGLMVAVGNLDYPLSQRNASISLEYFVRMYPFVEEHVRKAVGDTLFQLFKDCPETWYTKIDPVQAEELASNPVDSPKDMAKMQSAEGDQE", "length": 415, "header": "tr|A0A8V1A635-1|A0A8V1A8N5_CHICK Computationally mapped isoform of Armadillo like helical domain containing 1 OS=Gallus gallus OX=9031 GN=C1orf228 PE=4 SV=1 CANONICAL=A0A8V1A8N5-1" }, "locus": { "chromosome": "8", "start_pos": 20436646, "end_pos": 20426707, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010062531.1", "url": "https://www.ensembl.org/id/ENSGALT00010062531.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038664.1", "url": "https://www.ensembl.org/id/ENSGALP00010038664.1" } ] } }, { "isoform_ac": "A0A8V1A8N5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8N5/entry#A0A8V1A8N5-1", "sequence": { "sequence": "MTSVKEQEAIKKLMVFLQEWDSAHRVARNHILDNFIRSNIGKTEPELELEFSQGASLFLARLAAWLRVTYMYSTCINKLLKSIGIFLSAASGRRYIIEFLEMGGVLMLLEILGLNHLNEEDKRESVKLLQLIADAGRKYKELICESYGVQSLAELLATCSSAEVRDEVQILLDSLGRGNPKYQNQVYSGLLAVLPCGSPHAQQLALQTLRSMQDLLEEPPPAGVAPLLAALGTTHPEVQYEAVQLLLAVASRRAPPALLPGLVALLTPPGRKARAKDPMLPPREPTLAHVQQAAAAKAIGVLAKESAEVAEELIQLKVVHGLMVAVGNLDYPLSQRNASISLEYFVRMYPFVEEHVRKAVGDTLFQLFKDCPETWYTKIDPVQAEELASNPVDSPKDMAKMQSAEAGCPLTDLSGDNHYFATSFFLPIHKIYGEFRAFEEDQHALVQNNF", "length": 450, "header": "tr|A0A8V1A8N5-1|A0A8V1A8N5_CHICK Isoform 1 of Armadillo like helical domain containing 1 OS=Gallus gallus OX=9031 GN=C1orf228 PE=4 SV=1 CANONICAL=A0A8V1A8N5-1" }, "locus": { "chromosome": "8", "start_pos": 20447521, "end_pos": 20426797, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010062536.1", "url": "https://www.ensembl.org/id/ENSGALT00010062536.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038668.1", "url": "https://www.ensembl.org/id/ENSGALP00010038668.1" } ] } }, { "isoform_ac": "A0A8V1AB64-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8N5/entry#A0A8V1AB64-1", "sequence": { "sequence": "MAKEIMTSVKEQEAIKKLMVFLQEWDSAHRVARNHILDNFIRSNIGKTEPELELEFSQGASLFLARLAAWLRVTYMYSTCINKLLKSIGIFLSAASGRRYIIEFLEMGGVLMLLEILGLNHLNEEDKRESVKLLQLIADAGRKYKELICESYGVQSLAELLATCSSAEVRDEVQILLDSLGRGNPKYQNQVYSGLLAVLPCGSPHAQQLALQTLRSMQDLLEEPPPAGVAPLLAALGTTHPEVQYEAVQLLLAVASRRAPPALLPGLVALLTPPGRKARAKDPMLPPREPTLAHVQQAAAAKAIGVLAKESAEVAEELIQLKVVHGLMVAVGNLDYPLSQRNASISLEYFVRMYPFVEEHVRKAVGDTLFQLFKDCPETWYTKIDPVQAEELASNPVDSPKDMAKMQSAEGDQE", "length": 414, "header": "tr|A0A8V1AB64-1|A0A8V1AB64_CHICK Computationally mapped isoform of Armadillo like helical domain containing 1 OS=Gallus gallus OX=9031 GN=C1orf228 PE=4 SV=1 CANONICAL=A0A8V1A8N5-1" }, "locus": { "chromosome": "8", "start_pos": 20436646, "end_pos": 20426660, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010062533.1", "url": "https://www.ensembl.org/id/ENSGALT00010062533.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038666.1", "url": "https://www.ensembl.org/id/ENSGALP00010038666.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A8N5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8N5" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A8N5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8N5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 337, "end_pos": 339, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 337, "end_pos": 339 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A8U0-1", "uniprot_ac": "A0A8V1A8U0", "uniprot_id": "A0A8V1A8U0_CHICK", "mass": { "chemical_mass": 54949.0, "monoisotopic_mass": 54949.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "IF rod domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8V1A8U0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8U0/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A8U0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8U0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8U0", "locus": {} } ], "crossref": [ { "id": "A0A8V1A8U0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A8U0", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR002957", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002957", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018039", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018039", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039008", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039008", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A6C7", "url": "https://www.orthodb.org/?gene=A0A8V1A6C7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A8U0", "url": "https://www.orthodb.org/?gene=A0A8V1A8U0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23239", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23239", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23239:SF372", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23239:SF372", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00038", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00038", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-6805567", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6805567", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-6809371", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6809371", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1A6C7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6C7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A6C7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6C7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A8U0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8U0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A8U0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8U0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSCSIKQTTGSLRGRTSGGSCVIGGGGGGGGARMSSVSSGRYTTCGIGGSRGFSGRSYCGGVNYGGGLSSGSLVGGSYGGGLGAAVLGGCSGIGFSGGSARFGGGIGGGLGISLGGGVVGGGFSGDGILLSGDEKVTMQNLNDRLASYLDKVRCLEQENADLECRIREWYAKQGPFCEPRDYSCYYKEIEDLQNQIVCATIDNNKIILNIDNSRMTADDFRVKYETELALRQSVEADINGLRQSVEADINGLRQVLDQLTLCRSDLEAQLESLREELCCLKKNHEEEMNCLRKQSTGDVSVEVNACPGPDLRQILEDLRCQYETLIARNRKEVEDWYECKIEEVNREVITSGQEVETCNNQVTELRRQLQALEIDLQAQLSQRNNLESSLAETECQYNTLLGELQNQITCVEQQLAEIRAEIECQNQEYKTLLDVKCRLEQEIQTYRCLLEGGQQDLIHGGGIGVGSGVGGGVIRTSHTYTTTTASHCQPQVPPCKTGDIQVTCRRICD", "length": 509, "header": "tr|A0A8V1A8U0-1|A0A8V1A8U0_CHICK Isoform 1 of IF rod domain-containing protein OS=Gallus gallus OX=9031 GN= PE=1 SV=1 CANONICAL=A0A8V1A8U0-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A6C7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8U0/entry#A0A8V1A6C7-1", "sequence": { "sequence": "MSCSIKQTTGSLRGRTSGGSCVIGGGGGGGGARMSSVSSGRYTTCGIGGSRGFSGRSYCGGVNYGGGLSSGSLVGGSYGGGLGAAVLGGCSGIGFSGGSARFGGGIGGGLGISLGGGVVGGGFSGDGILLSGDEKVTMQNLNDRLASYLDKVRCLEQENADLECRIREWYAKQGPFCEPRDYSCYYKEIEDLQNQIVCATIDNNKIILNIDNSRMTADDFRVKYETELALRQSVEADINGLRQVLDQLTLCRSDLEAQLESLREELCCLKKNHEEEMNCLRKQSTGDVSVEVNACPGPDLRKILEEMRCQYETLIERNRKEVEDWYECKIEEVNREVITSGQEVETCNNQVTELRRQLQALEIDLQAQLSQRDNLESSLAETECRYNNHLGELQTQITCVEQQLADLRAEMECQNQEYKILLDVKCRLEQEIHTYRCLLEGGQQDLIQQGGIGQLSGLGGGVARTGGIGGGGIIRTSHTYTSSAQMPSCAAAEIQVPCRRICD", "length": 503, "header": "tr|A0A8V1A6C7-1|A0A8V1A8U0_CHICK Computationally mapped isoform of IF rod domain-containing protein OS=Gallus gallus OX=9031 GN= PE=1 SV=1 CANONICAL=A0A8V1A8U0-1" }, "locus": { "chromosome": "27", "start_pos": 4605812, "end_pos": 4601379, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010064848.1", "url": "https://www.ensembl.org/id/ENSGALT00010064848.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039639.1", "url": "https://www.ensembl.org/id/ENSGALP00010039639.1" } ] } }, { "isoform_ac": "A0A8V1A8U0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8U0/entry#A0A8V1A8U0-1", "sequence": { "sequence": "MSCSIKQTTGSLRGRTSGGSCVIGGGGGGGGARMSSVSSGRYTTCGIGGSRGFSGRSYCGGVNYGGGLSSGSLVGGSYGGGLGAAVLGGCSGIGFSGGSARFGGGIGGGLGISLGGGVVGGGFSGDGILLSGDEKVTMQNLNDRLASYLDKVRCLEQENADLECRIREWYAKQGPFCEPRDYSCYYKEIEDLQNQIVCATIDNNKIILNIDNSRMTADDFRVKYETELALRQSVEADINGLRQSVEADINGLRQVLDQLTLCRSDLEAQLESLREELCCLKKNHEEEMNCLRKQSTGDVSVEVNACPGPDLRQILEDLRCQYETLIARNRKEVEDWYECKIEEVNREVITSGQEVETCNNQVTELRRQLQALEIDLQAQLSQRNNLESSLAETECQYNTLLGELQNQITCVEQQLAEIRAEIECQNQEYKTLLDVKCRLEQEIQTYRCLLEGGQQDLIHGGGIGVGSGVGGGVIRTSHTYTTTTASHCQPQVPPCKTGDIQVTCRRICD", "length": 509, "header": "tr|A0A8V1A8U0-1|A0A8V1A8U0_CHICK Isoform 1 of IF rod domain-containing protein OS=Gallus gallus OX=9031 GN= PE=1 SV=1 CANONICAL=A0A8V1A8U0-1" }, "locus": { "chromosome": "27", "start_pos": 4605812, "end_pos": 4592119, "strand": "+", "evidence": [ { "database": "Ensembl 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"pmid": "" }, { "name": "lipid droplet", "id": "GO:0005811", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005811", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A948", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A948" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A948", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A948" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A948", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A948" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A948", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A948" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 213, "end_pos": 215, "annotation": "n_glycosylation_sequon" }, { "start_pos": 432, "end_pos": 434, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-GGA-1482647", "name": "2-MAG and DAG are transacylated to TAG by PNPLA2/3", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, endoplasmic reticulum membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A1D5PXZ3-1", "A0A8V1A948-1" ], "evidence": [ { "id": "R-GGA-1482647", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1482647" } ] }, { "id": "R-GGA-1482654", "name": "2-MAG is transacylated to DAG by PNPLA2/3", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, endoplasmic reticulum membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A1D5PXZ3-1", "A0A8V1A948-1" ], "evidence": [ { "id": "R-GGA-1482654", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1482654" } ] }, { "id": "R-GGA-1482777", "name": "TAG is hydrolyzed to DAG by PNPLA2/3", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, endoplasmic reticulum membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A1D5PXZ3-1", "A0A8V1A948-1" ], "evidence": [ { "id": "R-GGA-1482777", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1482777" } ] }, { "id": "R-GGA-1482811", "name": "DAG is hydrolyzed to 2-MAG by PNPLA2/3", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, endoplasmic reticulum membrane", "input_participant_list": [], "output_participant_list": [ "R-ALL-1498728" ], "enzyme_list": [ "A0A1D5PXZ3-1", "A0A8V1A948-1" ], "evidence": [ { "id": "R-GGA-1482811", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1482811" } ] }, { "id": "R-GGA-8952289", "name": "FAM20C phosphorylates FAM20C substrates", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "endoplasmic reticulum lumen", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0X453-1", "A0A8V0XGH4-1", "A0A8V1AL50-1", "A0A8V1A1S2-1", "A0A8V0YTC7-1", "A0A8V0ZTG6-1", "E1BS94-1", "A0A8V1A948-1", "A0A8V0Y248-1" ], "evidence": [ { "id": "R-GGA-8952289", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8952289" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-1498728", "participant_name": "2-MAG [endoplasmic reticulum membrane]", "crossref": [ { "id": "17389", "database": "ChEBI", "url": "" }, { "id": "C02112", "database": "COMPOUND", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5PXZ3", "gene_name": "PNPLA3", "activity": [ { "ec_number": "3.1.1.3", "activity": "a triacylglycerol + H2O = a diacylglycerol + a fatty acid + H(+).", "evidence": [ { "id": "A0A1D5PXZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PXZ3" } ] }, { "ec_number": "3.1.1.3", "activity": "", "evidence": [ { "id": "A0A1D5PXZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PXZ3" } ] } ] }, { "uniprot_ac": "A0A8V0X453", "gene_name": "CP", "activity": [ { "ec_number": "1.11.1.27", "activity": "a hydroperoxide + 2 glutathione = an alcohol + glutathione disulfide + H2O.", "evidence": [ { "id": "A0A8V0X453", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X453" } ] }, { "ec_number": "1.16.3.1", "activity": "4 Fe(2+) + O2 + 4 H(+) = 4 Fe(3+) + 2 H2O.", "evidence": [ { "id": "A0A8V0X453", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X453" } ] }, { "ec_number": "1.11.1.9", "activity": "2 glutathione + H2O2 = glutathione disulfide + 2 H2O.", "evidence": [ { "id": "A0A8V0X453", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X453" } ] }, { "ec_number": "1.16.3.4", "activity": "4 Cu(+) + O2 + 4 H(+) = 4 Cu(2+) + 2 H2O.", "evidence": [ { "id": "A0A8V0X453", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X453" } ] }, { "ec_number": "1.11.1.27", "activity": "", "evidence": [ { "id": "A0A8V0X453", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X453" } ] }, { "ec_number": "1.16.3.1", "activity": "", "evidence": [ { "id": "A0A8V0X453", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X453" } ] }, { "ec_number": "1.16.3.4", "activity": "", "evidence": [ { "id": "A0A8V0X453", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X453" } ] }, { "ec_number": "1.11.1.9", "activity": "", "evidence": [ { "id": "A0A8V0X453", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X453" } ] } ] }, { "uniprot_ac": "A0A8V0XGH4", "gene_name": "PDIA6", "activity": [ { "ec_number": "5.3.4.1", "activity": "Catalyzes the rearrangement of -S-S- bonds in proteins.", "evidence": [ { "id": "A0A8V0XGH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XGH4" } ] }, { "ec_number": "5.3.4.1", "activity": "", "evidence": [ { "id": "A0A8V0XGH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XGH4" } ] } ] }, { "uniprot_ac": "A0A8V0Y248", "gene_name": "QSOX1", "activity": [ { "ec_number": "1.8.3.2", "activity": "2 R'C(R)SH + O2 = R'C(R)S-S(R)CR' + H2O2.", "evidence": [ { "id": "A0A8V0Y248", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y248" } ] }, { "ec_number": "1.8.3.2", "activity": "", "evidence": [ { "id": "A0A8V0Y248", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y248" } ] } ] }, { "uniprot_ac": "A0A8V0YTC7", "gene_name": "MGAT4A", "activity": [ { "ec_number": "2.4.1.145", "activity": "N(4)-{beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)-[beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc}-L-asparaginyl-[protein] + UDP-N-acetyl-alpha-D-glucosamine = N(4)-{beta-D-GlcNAc-(1->2)-[beta-D-GlcNAc-(1->4)]-alpha-D-Man-(1->3)-[beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc}-L-asparaginyl-[protein] + UDP + H(+).", "evidence": [ { "id": "A0A8V0YTC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTC7" } ] }, { "ec_number": "2.4.1.145", "activity": "", "evidence": [ { "id": "A0A8V0YTC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTC7" } ] } ] }, { "uniprot_ac": "A0A8V0ZTG6", "gene_name": "PROC", "activity": [ { "ec_number": "3.4.21.69", "activity": "Degradation of blood coagulation factors Va and VIIIa.", "evidence": [ { "id": "A0A8V0ZTG6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTG6" } ] }, { "ec_number": "3.4.21.69", "activity": "", "evidence": [ { "id": "A0A8V0ZTG6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTG6" } ] } ] }, { 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"field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A9F2-1", "uniprot_ac": "A0A8V1A9F2", "uniprot_id": "A0A8V1A9F2_CHICK", "mass": { "chemical_mass": 83515.0, "monoisotopic_mass": 83515.0 }, "refseq": { "ac": "NP_989846", "name": "interleukin-17 receptor D precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989846" }, "gene_names": [ { "name": "IL17RD", "type": "recommended", "evidence": [ { "id": "A0A8V1A9F2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9F2" } ] }, { "name": "IL17RD", "type": "synonym", "evidence": [ { "id": "NP_989846", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989846" } ] }, { "name": "SEF", "type": "synonym", "evidence": [ { "id": "NP_989846", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989846" } ] } ], "protein_names": [ { "name": "Interleukin-17 receptor D", "type": "recommended", "evidence": [ { "id": "A0A8V1A9F2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9F2/entry#names_and_taxonomy" } ] }, { "name": "IL-17 receptor D", "type": "synonym", "evidence": [ { "id": "NP_989846", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989846" } ] }, { "name": "IL-17RD", "type": "synonym", "evidence": [ { "id": "NP_989846", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989846" } ] }, { "name": "cSEF", "type": "synonym", "evidence": [ { "id": "NP_989846", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989846" } ] }, { "name": "interleukin-17 receptor D precursor", "type": "synonym", "evidence": [ { "id": "NP_989846", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989846" } ] }, { "name": "sef homolog", "type": "synonym", "evidence": [ { "id": "NP_989846", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989846" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AY278204.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000252.1. On Sep 23, 2021 this sequence version replaced NP_989846.1.", "evidence": [ { "database": "RefSeq", "id": "NP_989846", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989846" } ] }, { "annotation": "The anterior expression is not fixed in the period of limb development, but the expression domains of Mkp3, Sef and TSK change considerably from the distal domain to the anterior domain", "evidence": [ { "database": "RefSeq", "id": "NP_989846", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989846" }, { "database": "PubMed", "id": "20100248", "url": "https://glygen.org/publication/PubMed/20100248" } ] }, { "annotation": "The spatiotemporal pattern of cSef expression during limb development suggests a role for cSef in regulating limb outgrowth but not limb initiation", "evidence": [ { "database": "RefSeq", "id": "NP_989846", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989846" }, { "database": "PubMed", "id": "15844098", "url": "https://glygen.org/publication/PubMed/15844098" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9F2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9F2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "IL17RD", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9F2", "locus": { "chromosome": "12", "start_pos": 8730984, "end_pos": 8791278, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027043", "url": "https://www.ensembl.org/id/ENSGALG00010027043" } ] } } ], "crossref": [ { "id": "A0A8V1A9F2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A9F2", "database": "AlphaFoldDB", "categories": [] }, { "id": "395186", "url": "https://www.ncbi.nlm.nih.gov/gene/395186", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013568", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013568", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031951", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031951", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035897", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035897", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039465", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039465", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:395186", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395186", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KNCKEDQ", "url": "https://omabrowser.org/oma/group/KNCKEDQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A6W9", "url": "https://www.orthodb.org/?gene=A0A8V1A6W9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A9F2", "url": "https://www.orthodb.org/?gene=A0A8V1A9F2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A9F6", "url": "https://www.orthodb.org/?gene=A0A8V1A9F6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AEC6", "url": "https://www.orthodb.org/?gene=A0A8V1AEC6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15583", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15583", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15583:SF14", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15583:SF14", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08357", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08357", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16742", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16742", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_989846", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989846", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1A6W9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6W9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A6W9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6W9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A9F2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9F2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A9F2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9F2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A9F6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9F6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A9F6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9F6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AEC6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEC6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AEC6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEC6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAPGRELGAFLLALLAFCGGRRLAEAAGGPGGRRGAAADACGGRGLSSVTKSNGLLNITFKYDNCTPYLNSVGKHVIGDVQNITISQYACYEQVAVTILWTANAIGIEYLRGFRVILEELKSEGRQCQQMVLRDPKQLSPSFKRTGMESNPFANLKFETDYFVKIVPFPSIKNESNYHPFFFRTRPCELLLQPENLICKPYWKPRNLNVTQQGFNMQVSFDHAPHNFGFRYYFLHYKLKHEGPFKQKTCKQDQNTDTTSCILQNVTPGDYIIELVDDTNTTRKTMHYALKPVHSPWAGPIRAIAITVPLVVISAFATLFTVMCRKKQQENIYSHLDEESSESSAYGAGLPVERLRPRPKVFICYSSKDCQKHINVIQCFAYFLQDFCGCEVALDLWEDLKICKESQKEWLIKKINESQFIIIVCSKGMKYFVEKKNWKHRGVTKDTGKGELFLFAVFTVAEKLRQAKQNSNDLCKFIAVYFDYSCEGDIPGILDLSTKYKLMDNLPQLYSHLHSRDLSVQDSEVFPVNVSKRNYFRSKSGRSLYVAICNMHQFIDQEPDWFEKQFIPFLPHPLHYSEPVMEKFDSGLVLNDLVNKQAADDDFYLKTDVNIISAGSSDSHCIIQHLNLGEDVETQDIQSGSSSVLRPLLHAVKASNLKDMPRDSGIYDSSVPSSELSLPLMEGLLTDQTETSSITGSVSSSSGLGEEEPPVITSTKFLLPGICKAELHCHIHTDELQAIAPL", "length": 741, "header": "tr|A0A8V1A9F2-1|A0A8V1A9F2_CHICK Isoform 1 of Interleukin-17 receptor D OS=Gallus gallus OX=9031 GN=IL17RD PE=4 SV=1 CANONICAL=A0A8V1A9F2-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A6W9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9F2/entry#A0A8V1A6W9-1", "sequence": { "sequence": "MLLQAVPESNAILLRAVTSFTSGLSSVTKSNGLLNITFKYDRIEYLRGFRVILEELKSEGRQCQQMVLRDPKQLSPSFKRTGMESNPFANLKFETDYFVKIVPFPSIKNESNYHPFFFRTRPCELLLQPENLICKPYWKPRNLNVTQQGFNMQVSFDHAPHNFGFRYYFLHYKLKHEGPFKQKTCKQDQNTDTTSCILQNVTPGDYIIELVDDTNTTRKTMHYALKPVHSPWAGPIRAIAITVPLVVISAFATLFTVMCRKKQQENIYSHLDEESSESSAYGAGLPVERLRPRPKVFICYSSKDCQKHINVIQCFAYFLQDFCGCEVALDLWEDLKICKESQKEWLIKKINESQFIIIVCSKGMKYFVEKKNWKHRGVTKDTGKGELFLFAVFTVAEKLRQAKQNSNDLCKFIAVYFDYSCEGDIPGILDLSTKYKLMDNLPQLYSHLHSRDLSVQDSEVFPVNVSKRNYFRSKSGRSLYVAICNMHQFIDQEPDWFEKQFIPFLPHPLHYSEPVMEKFDSGLVLNDLVNKQAADDDFYLKTDVNIISAGSSDSHCIIQHLNLGEDVETQDIQSGSSSVLRPLLHAVKASNLKDMPRDSGIYDSSVPSSELSLPLMEGLLTDQTETSSITGSVSSSSGLGEEEPPVITSTKFLLPGICKAELHCHIHTDELQAIAPL", "length": 677, "header": "tr|A0A8V1A6W9-1|A0A8V1A9F2_CHICK Computationally mapped isoform of Interleukin-17 receptor D OS=Gallus gallus OX=9031 GN=IL17RD PE=4 SV=1 CANONICAL=A0A8V1A9F2-1" }, "locus": { "chromosome": "12", "start_pos": 8773053, "end_pos": 8734425, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065569.1", "url": "https://www.ensembl.org/id/ENSGALT00010065569.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039864.1", "url": "https://www.ensembl.org/id/ENSGALP00010039864.1" } ] } }, { "isoform_ac": "A0A8V1A9F2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9F2/entry#A0A8V1A9F2-1", "sequence": { "sequence": "MAPGRELGAFLLALLAFCGGRRLAEAAGGPGGRRGAAADACGGRGLSSVTKSNGLLNITFKYDNCTPYLNSVGKHVIGDVQNITISQYACYEQVAVTILWTANAIGIEYLRGFRVILEELKSEGRQCQQMVLRDPKQLSPSFKRTGMESNPFANLKFETDYFVKIVPFPSIKNESNYHPFFFRTRPCELLLQPENLICKPYWKPRNLNVTQQGFNMQVSFDHAPHNFGFRYYFLHYKLKHEGPFKQKTCKQDQNTDTTSCILQNVTPGDYIIELVDDTNTTRKTMHYALKPVHSPWAGPIRAIAITVPLVVISAFATLFTVMCRKKQQENIYSHLDEESSESSAYGAGLPVERLRPRPKVFICYSSKDCQKHINVIQCFAYFLQDFCGCEVALDLWEDLKICKESQKEWLIKKINESQFIIIVCSKGMKYFVEKKNWKHRGVTKDTGKGELFLFAVFTVAEKLRQAKQNSNDLCKFIAVYFDYSCEGDIPGILDLSTKYKLMDNLPQLYSHLHSRDLSVQDSEVFPVNVSKRNYFRSKSGRSLYVAICNMHQFIDQEPDWFEKQFIPFLPHPLHYSEPVMEKFDSGLVLNDLVNKQAADDDFYLKTDVNIISAGSSDSHCIIQHLNLGEDVETQDIQSGSSSVLRPLLHAVKASNLKDMPRDSGIYDSSVPSSELSLPLMEGLLTDQTETSSITGSVSSSSGLGEEEPPVITSTKFLLPGICKAELHCHIHTDELQAIAPL", "length": 741, "header": "tr|A0A8V1A9F2-1|A0A8V1A9F2_CHICK Isoform 1 of Interleukin-17 receptor D OS=Gallus gallus OX=9031 GN=IL17RD PE=4 SV=1 CANONICAL=A0A8V1A9F2-1" }, "locus": { "chromosome": "12", "start_pos": 8771940, "end_pos": 8734425, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065558.1", "url": "https://www.ensembl.org/id/ENSGALT00010065558.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039856.1", "url": "https://www.ensembl.org/id/ENSGALP00010039856.1" } ] } }, { "isoform_ac": "A0A8V1A9F6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9F2/entry#A0A8V1A9F6-1", "sequence": { "sequence": "MLDLASDFQKLRMGYVELSPVEIELLGGSYSKCTRSIKMLLQAVPESNAILLRAVTSFTSGLSSVTKSNGLLNITFKYDNCTPYLNSVGKHVIGDVQNITISQYACYEQVAVTILWTANAIGIEYLRGFRVILEELKSEGRQCQQMVLRDPKQLSPSFKRTGMESNPFANLKFETDYFVKIVPFPSIKNESNYHPFFFRTRPCELLLQPENLICKPYWKPRNLNVTQQGFNMQVSFDHAPHNFGFRYYFLHYKLKHEGPFKQKTCKQDQNTDTTSCILQNVTPGDYIIELVDDTNTTRKTMHYALKPVHSPWAGPIRAIAITVPLVVISAFATLFTVMCRKKQQENIYSHLDEESSESSAYGAGLPVERLRPRPKVFICYSSKDCQKHINVIQCFAYFLQDFCGCEVALDLWEDLKICKESQKEWLIKKINESQFIIIVCSKGMKYFVEKKNWKHRGVTKDTGKGELFLFAVFTVAEKLRQAKQNSNDLCKFIAVYFDYSCEGDIPGILDLSTKYKLMDNLPQLYSHLHSRDLSVQDSEVFPVNVSKRNYFRSKSGRSLYVAICNMHQFIDQEPDWFEKQFIPFLPHPLHYSEPVMEKFDSGLVLNDLVNKQAADDDFYLKTDVNIISAGSSDSHCIIQHLNLGEDVETQDIQSGSSSVLRPLLHAVKASNLKDMPRDSGIYDSSVPSSELSLPLMEGLLTDQTETSSITGSVSSSSGLGEEEPPVITSTKFLLPGICKAELHCHIHTDELQAIAPL", "length": 757, "header": "tr|A0A8V1A9F6-1|A0A8V1A9F6_CHICK Computationally mapped isoform of Interleukin-17 receptor D OS=Gallus gallus OX=9031 GN=IL17RD PE=4 SV=1 CANONICAL=A0A8V1A9F2-1" }, "locus": { "chromosome": "12", "start_pos": 8777466, "end_pos": 8734425, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065566.1", "url": "https://www.ensembl.org/id/ENSGALT00010065566.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039861.1", "url": "https://www.ensembl.org/id/ENSGALP00010039861.1" } ] } }, { "isoform_ac": "A0A8V1AEC6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9F2/entry#A0A8V1AEC6-1", "sequence": { "sequence": "MAPGRELGAFLLALLAFCGGRRLAEAAGGPGGRRGAAADACGGRGLSSVTKSNGLLNITFKYDRIEYLRGFRVILEELKSEGRQCQQMVLRDPKQLSPSFKRTGMESNPFANLKFETDYFVKIVPFPSIKNESNYHPFFFRTRPCELLLQPENLICKPYWKPRNLNVTQQGFNMQVSFDHAPHNFGFRYYFLHYKLKHEGPFKQKTCKQDQNTDTTSCILQNVTPGDYIIELVDDTNTTRKTMHYALKPVHSPWAGPIRAIAITVPLVVISAFATLFTVMCRKKQQENIYSHLDEESSESSAYGAGLPVERLRPRPKVFICYSSKDCQKHINVIQCFAYFLQDFCGCEVALDLWEDLKICKESQKEWLIKKINESQFIIIVCSKGMKYFVEKKNWKHRGVTKDTGKGELFLFAVFTVAEKLRQAKQNSNDLCKFIAVYFDYSCEGDIPGILDLSTKYKLMDNLPQLYSHLHSRDLSVQDSEVFPVNVSKRNYFRSKSGRSLYVAICNMHQFIDQEPDWFEKQFIPFLPHPLHYSEPVMEKFDSGLVLNDLVNKQAADDDFYLKTDVNIISAGSSDSHCIIQHLNLGEDVETQDIQSGSSSVLRPLLHAVKASNLKDMPRDSGIYDSSVPSSELSLPLMEGLLTDQTETSSITGSVSSSSGLGEEEPPVITSTKFLLPGICKAELHCHIHTDELQAIAPL", "length": 699, "header": "tr|A0A8V1AEC6-1|A0A8V1AEC6_CHICK Computationally mapped isoform of Interleukin-17 receptor D OS=Gallus gallus OX=9031 GN=IL17RD PE=4 SV=1 CANONICAL=A0A8V1A9F2-1" }, "locus": { "chromosome": "12", "start_pos": 8771940, "end_pos": 8734425, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065562.1", "url": "https://www.ensembl.org/id/ENSGALT00010065562.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039858.1", "url": "https://www.ensembl.org/id/ENSGALP00010039858.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 266, "start_aa": "Thr", "end_pos": 266, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr266", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "Sef is synexpressed with FGFs during chick embryogenesis and its expression is differentially regulated by FGFs in the developing limb.", "journal": "Developmental dynamics : an official publication of the American Association of Anatomists", "date": "2005-06", "authors": "Harduf Haggar, Halperin Einat, Reshef Ram, Ron Dina", "evidence": [ { "database": "RefSeq", "id": "NP_989846", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989846" } ], "reference": [ { "type": "PubMed", "id": "15844098", "url": "https://glygen.org/publication/PubMed/15844098" } ] }, { "title": "Anterior shift in gene expression precedes anteriormost digit formation in amniote limbs.", "journal": "Development, growth & differentiation", "date": "2010-02", "authors": "Uejima Asaka, Amano Takanori, Nomura Naoki, Noro Miyuki, Yasue Taiji, Shiroishi Toshihiko, Ohta Kunimasa, Yokoyama Hitoshi, Tamura Koji", "evidence": [ { "database": "RefSeq", "id": "NP_989846", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989846" } ], "reference": [ { "type": "PubMed", "id": "20100248", "url": "https://glygen.org/publication/PubMed/20100248" } ] } ], "pathway": [ { "id": "gga:395186", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395186", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZGQ0-1", "protein_name": "Interleukin-17 receptor D", "gene_name": "Il17rd", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAPWLQLCSFFFTVNACLNGSQLAVAAGGSGRARGADTCGWRGVGPASRNSGLYNITFRYDNCTTYLSPVGKHMIADAQNITISQYACNDQVAVTILWSPGALGIEFLKGFRVILEELRSEGRLCQQLVLKDPKQLNSSFKRTGMESQPFLNMKFETDYFVKIVPFPSIKNESDYHPFFFRTRACDLLLQPDNLACKPFWKPRNLNITQYGSDMQVSFHHAPQNFGFRGFHVHYKLKHEGPFRRRTCRQDQNTETTSCLLQNVSPGDYVIELVDDSNTTRKAAQYVVKPVQSPWAGPIRAVAITVPLVVISAFATLFTVMCRKKQQENIYSHLDEESPESSTYAAVLPRDRLRPRPKVFLCYSSKDGQNHMNVVQCFAYFLQEFCGCEVALDLWEDFSHCIEGQREWVIQKIHESQFIIVVCSKGMKYFVDKKSYRHKGGSRGGTGQGELFLVAVAAIAEKLRQAKQSSSAALSKFITVYFDYSCEGDVPCTLDLSTKYKLMDNLPELCSHLHSGEQEELGQHPGHSSRRNYFRSKAGRSLYVAICNMHQFIDEEPDWFEKQFVPFHPPPVRYQEPVLEKFDSGLVLNDVISKPGPESDFCLKVEASILGATGPADSYSYLENQHAGLDQDTEAQPACDGGPALQPLLHAVKAGSPSDMPRDSGIYDSSVPSSELSLPLMEGLSPDQIETSSLTESVSSSSGLGEEDPPTFPSKLLASGVSKGEHGFHSYTDELQAAAPL", "length": 740 }, "evidence": [ { "id": "A0A8V1A9F2", "url": "https://omabrowser.org/oma/group/A0A8V1A9F2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1SGL1-1", "protein_name": "Interleukin-17 receptor 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"MAPWLQLCSVFFTVNACLNGSQLAVAAGGSGRARGADTCGWRGVGPASRNSGLYNITFKYDNCTTYLNPVGKHVIADAQNITISQYACHDQVAVTILWSPGALGIEFLKGFRVILEELKSEGRQCQQLILKDPKQLNSSFKRTGMESQPFLNMKFETDYFVKVVPFPSIKNESNYHPFFFRTRACDLLLQPDNLACKPFWKPRNLNISQHGSDMQVSFDHAPHNFGFRFFYLHYKLKHEGPFKRKTCKQEQTTETTSCLLQNVSPGDYIIELVDDTNTTRKVMHYALKPVHSPWAGPIRAVAITVPLVVISAFATLFTVMCRKKQQENIYSHLDEESSESSTYTAALPRERLRPRPKVFLCYSSKDGQNHMNVVQCFAYFLQDFCGCEVALDLWEDFSLCREGQREWVIQKIHESQFIIVVCSKGMKYFVDKKNYKHKGGGRGSGKGELFLVAVSAIAEKLRQAKQSSSAALSKFIAVYFDYSCEGDVPGILDLSTKYRLMDNLPQLCSHLHSRDHGLQEPGQHTRQGSRRNYFRSKSGRSLYVAICNMHQFIDEEPDWFEKQFVPFHPPPLRYREPVLEKFDSGLVLNDVMCKPGPESDFCLKVEAAVLGATGPADSQHESQHGGLDQDGEARPALDGSAALQPLLHTVKAGSPSDMPRDSGIYDSSVPSSELSLPLMEGLSTDQTETSSLTESVSSSSGLGEEEPPALPSKLLSSGSCKADLGCRSYTDELHAVAPL", "length": 739 }, "evidence": [ { "id": "A0A8V1A9F2", "url": "https://omabrowser.org/oma/group/A0A8V1A9F2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", 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"https://www.ebi.ac.uk/QuickGO/term/GO:0030512", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9F2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9F2" } ], "pmid": "" }, { "name": "negative regulation of epithelial to mesenchymal transition", "id": "GO:0010719", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010719", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9F2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9F2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 173, "end_pos": 175, "annotation": "n_glycosylation_sequon" }, { "start_pos": 208, "end_pos": 210, "annotation": "n_glycosylation_sequon" }, { "start_pos": 264, "end_pos": 266, "annotation": "n_glycosylation_sequon" }, { "start_pos": 279, "end_pos": 281, "annotation": "n_glycosylation_sequon" }, { "start_pos": 415, "end_pos": 417, "annotation": "n_glycosylation_sequon" }, { "start_pos": 528, "end_pos": 530, "annotation": "n_glycosylation_sequon" }, { "start_pos": 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"publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8V1A6X0-1", "uniprot_ac": "A0A8V1A6X0", "uniprot_id": "A0A8V1A6X0_CHICK", "mass": { "chemical_mass": 72936.0, "monoisotopic_mass": 72936.0 }, "refseq": { "ac": "XP_040561973", "name": "secretogranin-2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040561973" }, "gene_names": [ { "name": "SCG2", "type": "recommended", "evidence": [ { "id": "A0A8V1A6X0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6X0" } ] }, { "name": "SCG2", "type": "synonym", "evidence": [ { "id": "XP_040561973", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040561973" } ] } ], "protein_names": [ { "name": "Secretogranin II", "type": "synonym", "evidence": [ { "id": "A0A8V1A6X0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6X0/entry#names_and_taxonomy" } ] }, { "name": "secretogranin-2", "type": "synonym", "evidence": [ { "id": "XP_040561973", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040561973" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052540.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040561973", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040561973" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A6X0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6X0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SCG2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6X0", "locus": { "chromosome": "9", "start_pos": 7899138, "end_pos": 7931606, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010025890", "url": "https://www.ensembl.org/id/ENSGALG00010025890" } ] } } ], "crossref": [ { "id": "101750767", "url": "https://www.ncbi.nlm.nih.gov/gene/101750767", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038858", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038858", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "RNAAYDD", "url": "https://omabrowser.org/oma/group/RNAAYDD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A6X0", "url": "https://www.orthodb.org/?gene=A0A8V1A6X0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15119", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15119", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15119:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15119:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01271", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01271", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-381426", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-381426", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-8957275", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8957275", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_040561973", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040561973", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1A6X0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6X0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A6X0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6X0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLNMAETKPIQLGAACAVTFFFVLICWADAASFQQYQLLQKDPDYVMKNLQRLPNPDMIKALEYIEDLRKQANKGESIPDYNSFQSVPYLLQQKENKDQVHLPENVRDSLTEDESQWVKVMLEALRQAEKESKGTKENKLYGLSSDNSFPAGVTDDYEAYKWPERWQKYLKMPLGHYEDSSRDSPFKRTNEIVEEQYTPQSLATLESVFQELGKMAGPSNHKKERLDEDQKLYADDEDDVYKVNNIAYEDVVGGEDWNPIEEKVESQTQEEIKDSKEEIDKHEEEVDDEMKRSGKLSFLEDEMRRENKDQMSEDVSKLMNYYLKRLMGSAGNRKLRTGGELEEKRAATILDKQLNPQSIAQLIEMSRNLQIPPEDLIDMFKPGEKKQLQSERLEAEQEAEFPEDLDEITETNLGQSDIFKNNVNSKNGYMKQPLNAIPENLPEDLNIEDIVSLLGTGNLGNQNPSYLLNRLNQENDLPRLPYIPRRLKGRPVAKSAWINDLERRQMEYEKLDEKDEELADYLAKMLAKYPEVINTNQMKRVPVPASESDLQEDERLEQAIREHLSQLGPQEAARLASLSKRLSMAGDTDDTQNRQYLDEDMLAKVLEYLKQEKSELERDHITKRAMENM", "length": 629, "header": "tr|A0A8V1A6X0-1|A0A8V1A6X0_CHICK Isoform 1 of Secretogranin II OS=Gallus gallus OX=9031 GN=SCG2 PE=1 SV=1 CANONICAL=A0A8V1A6X0-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A6X0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6X0/entry#A0A8V1A6X0-1", "sequence": { "sequence": "MLNMAETKPIQLGAACAVTFFFVLICWADAASFQQYQLLQKDPDYVMKNLQRLPNPDMIKALEYIEDLRKQANKGESIPDYNSFQSVPYLLQQKENKDQVHLPENVRDSLTEDESQWVKVMLEALRQAEKESKGTKENKLYGLSSDNSFPAGVTDDYEAYKWPERWQKYLKMPLGHYEDSSRDSPFKRTNEIVEEQYTPQSLATLESVFQELGKMAGPSNHKKERLDEDQKLYADDEDDVYKVNNIAYEDVVGGEDWNPIEEKVESQTQEEIKDSKEEIDKHEEEVDDEMKRSGKLSFLEDEMRRENKDQMSEDVSKLMNYYLKRLMGSAGNRKLRTGGELEEKRAATILDKQLNPQSIAQLIEMSRNLQIPPEDLIDMFKPGEKKQLQSERLEAEQEAEFPEDLDEITETNLGQSDIFKNNVNSKNGYMKQPLNAIPENLPEDLNIEDIVSLLGTGNLGNQNPSYLLNRLNQENDLPRLPYIPRRLKGRPVAKSAWINDLERRQMEYEKLDEKDEELADYLAKMLAKYPEVINTNQMKRVPVPASESDLQEDERLEQAIREHLSQLGPQEAARLASLSKRLSMAGDTDDTQNRQYLDEDMLAKVLEYLKQEKSELERDHITKRAMENM", "length": 629, "header": "tr|A0A8V1A6X0-1|A0A8V1A6X0_CHICK Isoform 1 of Secretogranin II OS=Gallus gallus OX=9031 GN=SCG2 PE=1 SV=1 CANONICAL=A0A8V1A6X0-1" }, "locus": { "chromosome": "9", "start_pos": 7902122, "end_pos": 7900236, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063096.1", "url": "https://www.ensembl.org/id/ENSGALT00010063096.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038946.1", "url": "https://www.ensembl.org/id/ENSGALP00010038946.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-381426", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-381426", "resource": "Reactome", "description": "Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)" }, { "id": "R-GGA-8957275", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8957275", "resource": "Reactome", "description": "Post-translational protein phosphorylation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A9J7K0X4-1", "protein_name": "Secretogranin-2", "gene_name": "Scg2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAEAKTHQFGALLLLVLISGAEAASFQRNQLVQKEPDLRLENVQKFPSPEMIRALEYIEKLRQQAHREESSPDYNPYQGISVPLQLKENIEESHLAESSRDALSEDEWMRIILEALRQAENEPQSTPKENKLFALNLEKNFPVDMVDDYETQQWPERKLKHMRFPLMYEENSRENPFKRTNEIVEEQYTPQSLATLESVFQELGKLTGPNNQKRERVDEEQKLYTDDEDDVYKNNNIAYEDVVGGEDWSPVEEKIETQTQEEVRDSKENTEANEQINEEMKRSGQLGLQDEDNRKESKDQLSEDASKVITYLRRLVNAVGSGRSQNGQNGDRAARLLEKPLDAQSIYQLIEISRNLQIPPEDLIEMLRAGEKPNALVEPEQDLELPVDLDDIPEADIDHPDMFQSKLLSKGGYSKVPGHGMIEALPEGLSVEDILNLLGMENEANQKPPYFPNQYSRDKALLRLPYGPGKARTNKIPKAAWMPEVESRQAPYENLINDKDQELGDYLARLLVKYPELLNSNQLKRVPSPGSSEDDLQEEEQLEQAIKEQLGQGSSQETEKLATVSKRLPAGSLKNDDALNRQYLDEDMLMKVLEYLTQEKAEQGKEHLAKRAMENM", "length": 616 }, "evidence": [ { "id": "A0A8V1A6X0", "url": "https://omabrowser.org/oma/group/A0A8V1A6X0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "I3LUV5-1", "protein_name": "Secretogranin-2", "gene_name": "SCG2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAEAKTHWLGASLSLILLIFLLATAEAASFQRNQLLQKEPDLRLENVQRFASPEMIRALEYIEKLRQQAHKEESSPDYNPYQGVSVPLQQKENSDLPESSRDSLSEDEWMKIILEALRQAENEPQSSLKENKPYTLNSEKNFPMDMPDDYETQQWPERKLKHMRFPPMYEENSRDNPFKRTNEIVEEQYTPQSLATLESVFQELGKLTGPNNQKRERVDEEQKLYTDDEDDIYKANNIAYEDVVGGEDWNPVEEKIESQTQEEVRDSKENIEKNEQINDEMKRSGQMGLQDEDLRKEGKDQLSEDVSKVIAYLKRLVNAVGSGKSQNGQNGERANRLFEKPLDSQSIYQLIELSRNLQIPPEDLIDMLKTGEKPNASVEPEQELEIPVDLDDISEVDLDHPDLFQNKMLSKNGYSKTPGRAVSEALPDGLSVEDILNLLGMENAANQKPPYFPNQYNREKILPRLPYGPGRAKANQLPKAVWMPDVENRQMAYDNLNDKDQELGEYLARMLVKYPEIMNSNQVKRVPSQGSSEDDLQEENQIEQAIKERLNQHSSQDTDKLALVSKRLPVATPKSDDAPNRQYLDEDLLMKVLEYLNQEKAEKGREHIAKRAMENM", "length": 616 }, "evidence": [ { "id": "A0A8V1A6X0", "url": "https://omabrowser.org/oma/group/A0A8V1A6X0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P10362-1", "protein_name": "Secretogranin-2", "gene_name": "Scg2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTESKAYRFGAVLLLIHLIFLVPGTEAASFQRNQLLQKEPDLRLENVQKFPSPEMIRALEYIEKLRQQAHREESSPDYNPYQGISVPLQLKENGEESHLAESSRDVLSEDEWMRIILEALRQAENEPPSALKENKPYALNLEKNFPVDTPDDYETQQWPERKLKHMRFPLMYEENSRENPFKRTNEIVEEQYTPQSLATLESVFQELGKLTGPSNQKRERVDEEQKLYTDDEDDVYKTNNIAYEDVVGGEDWSPMEEKIETQTQEEVRDSKENTEKNEQINEEMKRSGHLGLPDEGNRKESKDQLSEDASKVITYLRRLVNAVGSGRSQSGQNGDRAARLLERPLDSQSIYQLIEISRNLQIPPEDLIEMLKAGEKPNGLVEPEQDLELAVDLDDIPEADIDRPDMFQSKTLSKGGYPKAPGRGMMEALPDGLSVEDILNVLGMENVANQKSPYFPNQYSRDKALLRLPYGPGKSRANQIPKVAWIPDVESRQAPYDNLNDKDQELGEYLARMLVKYPELMNTNQLKRVPSPGSSEDDLQEEEQLEQAIKEHLGQGSSQEMEKLAKVSKRIPAGSLKNEDTPNRQYLDEDMLLKVLEYLNQEQAEQGREHLAKRAMENM", "length": 619 }, "evidence": [ { "id": "A0A8V1A6X0", "url": "https://omabrowser.org/oma/group/A0A8V1A6X0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P13521-1", "protein_name": "Secretogranin-2", "gene_name": "SCG2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAEAKTHWLGAALSLIPLIFLISGAEAASFQRNQLLQKEPDLRLENVQKFPSPEMIRALEYIENLRQQAHKEESSPDYNPYQGVSVPLQQKENGDESHLPERDSLSEEDWMRIILEALRQAENEPQSAPKENKPYALNSEKNFPMDMSDDYETQQWPERKLKHMQFPPMYEENSRDNPFKRTNEIVEEQYTPQSLATLESVFQELGKLTGPNNQKRERMDEEQKLYTDDEDDIYKANNIAYEDVVGGEDWNPVEEKIESQTQEEVRDSKENIEKNEQINDEMKRSGQLGIQEEDLRKESKDQLSDDVSKVIAYLKRLVNAAGSGRLQNGQNGERATRLFEKPLDSQSIYQLIEISRNLQIPPEDLIEMLKTGEKPNGSVEPERELDLPVDLDDISEADLDHPDLFQNRMLSKSGYPKTPGRAGTEALPDGLSVEDILNLLGMESAANQKTSYFPNPYNQEKVLPRLPYGAGRSRSNQLPKAAWIPHVENRQMAYENLNDKDQELGEYLARMLVKYPEIINSNQVKRVPGQGSSEDDLQEEEQIEQAIKEHLNQGSSQETDKLAPVSKRFPVGPPKNDDTPNRQYWDEDLLMKVLEYLNQEKAEKGREHIAKRAMENM", "length": 617 }, "evidence": [ { "id": "A0A8V1A6X0", "url": "https://omabrowser.org/oma/group/A0A8V1A6X0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P20616-1", "protein_name": "Secretogranin-2", "gene_name": "SCG2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAEAKTHWLGAVLSLIPLIFLLSEAEAASFQRNQLLQKEPDLRLENVQRFPSPEMIRALEYIEKLRQQAHKEESSPDYNPYQGVSVPLQQKENGDLPESSRDSLSEDEWMKIIAEALRQAENEPQSAPKENKPYTLNSEKNFPMDMPDDYETQQWAERKLKHMRFPPMYEENSRDNPFKRTNEIVEEQYTPQNLATLESVFQELGKLTGPNSQKRERADEEQKLYTDDEDDIYKANNIAYEDVVGGEDWNPVEEKIESQTQEEVRDSKENADKTEQINDEMKRSGQLGLQDEDLRKESKDQLSDDVSKVITYLKRLVNAAGSGRSQNGQTGERAIRLFEKPLDPQSIYQLIEISRNLQIPPEDLIDMLKTGEKPVEPEQELEIPVEPEDISEVDLDHPDLFQNKMLSKNGYPKAPGHAVAEALSEGLSVEDILNLLGMESAANPKPPYFPNQYNREKVLSRLPYGPGRSKANQLPKAVWMPDVENRQMAYENLNDKDQELGEYLARMLVKYPEIMNANPAKRVPSQGSTEDDRQDENQIEQALKEHLSQHSSQETDKLASVSKRLPVGTPKSDDTPNRPYLDEDLLVKVLEYLNQEKAEKGREHIAKRAMENM", "length": 613 }, "evidence": [ { "id": "A0A8V1A6X0", "url": "https://omabrowser.org/oma/group/A0A8V1A6X0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q03517-1", "protein_name": "Secretogranin-2", "gene_name": "Scg2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAGAKAYRLGAVLLLIHLIFLISGAEAASFQRNQLLQKEPDLRLENVQKFPSPEMIRALEYIEKLRQQAHREESSPDYNPYQGVSVPLQLKENGEESHLAESSRDALSEDEWMRIILEALRQAENEPPSAPKENKPYALNLEKNFPVDTPDDYETQQWPERKLKHMRFPLMYEENSRENPFKRTNEIVEEQYTPQSLATLESVFQELGKLTGPSNQKRERVDEEQKLYTDDEDDVYKTNNIAYEDVVGGEDWSPIEEKIETQTQEEVRDSKENTEKNEQINEEMKRSGQLGLPDEENRRESKDQLSEDASKVITYLRRLVNAVGSGRSQSGPNGDRAARLLQKPLDSQSIYQLIEISRNLQIPPEDLIEMLKAGEKPNGLVEPEQDLELAVDLDDIPEADLDRPDMFQSKMLSKGGYPKAPGRGMVEALPDGLSVEDILNVLGMENVVNQKSPYFPNQYSQDKALMRLPYGPGKSRANQIPKVAWIPDVESRQAPYENLNDQELGEYLARMLVKYPELLNTNQLKRVPSPVSSEDDLQEEEQLEQAIKEHLGPGSSQEMERLAKVSKRIPVGSLKNEDTPNRQYLDEDMLLKVLEYLNQEQAEQGREHLAKRAMENM", "length": 617 }, "evidence": [ { "id": "A0A8V1A6X0", "url": "https://omabrowser.org/oma/group/A0A8V1A6X0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "neuronal dense core vesicle", "id": "GO:0098992", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098992", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A6X0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6X0" } ], "pmid": "" }, { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A6X0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6X0" } ], "pmid": "" }, { "name": "secretory granule", "id": "GO:0030141", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030141", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A6X0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6X0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "angiogenesis", "id": "GO:0001525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001525", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A6X0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6X0" } ], "pmid": "" }, { "name": "MAPK cascade", "id": "GO:0000165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000165", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A6X0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6X0" } ], "pmid": "" }, { "name": "positive regulation of endothelial cell proliferation", "id": "GO:0001938", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001938", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A6X0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6X0" } ], "pmid": "" }, { "name": "negative regulation of endothelial cell apoptotic process", "id": "GO:2000352", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000352", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A6X0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6X0" } ], "pmid": "" }, { "name": "negative regulation of extrinsic apoptotic signaling pathway", "id": "GO:2001237", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2001237", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A6X0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6X0" } ], "pmid": "" }, { "name": "induction of positive chemotaxis", "id": "GO:0050930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050930", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A6X0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6X0" } ], "pmid": "" }, { "name": "eosinophil chemotaxis", "id": "GO:0048245", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048245", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A6X0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6X0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "chemoattractant activity", "id": "GO:0042056", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042056", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A6X0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6X0" } ], "pmid": "" }, { "name": "cytokine activity", "id": "GO:0005125", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005125", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A6X0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6X0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A6X1-1", "uniprot_ac": "A0A8V1A6X1", "uniprot_id": "A0A8V1A6X1_CHICK", "mass": { "chemical_mass": 159342.0, "monoisotopic_mass": 159342.0 }, "refseq": { "ac": "XP_015148236", "name": "nischarin isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015148236" }, "gene_names": [ { "name": "NISCH", "type": "recommended", "evidence": [ { "id": "A0A8V1A6X1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6X1" } ] }, { "name": "NISCH", "type": "synonym", "evidence": [ { "id": "XP_015148236", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015148236" } ] } ], "protein_names": [ { "name": "Nischarin", "type": "recommended", "evidence": [ { "id": "A0A8V1A6X1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6X1/entry#names_and_taxonomy" } ] }, { "name": "Imidazoline receptor 1", "type": "synonym", "evidence": [ { "id": "A0A8V1A6X1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6X1/entry#names_and_taxonomy" } ] }, { "name": "Imidazoline-1 receptor", "type": "synonym", "evidence": [ { "id": "A0A8V1A6X1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6X1/entry#names_and_taxonomy" } ] }, { "name": "nischarin isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015148236", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015148236" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052543.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015148236.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015148236", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015148236" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A6X1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6X1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NISCH", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6X1", "locus": { "chromosome": "12", "start_pos": 684380, "end_pos": 649902, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028031", "url": "https://www.ensembl.org/id/ENSGALG00010028031" } ] } } ], "crossref": [ { "id": "cd06875", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06875", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "415893", "url": "https://www.ncbi.nlm.nih.gov/gene/415893", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001683", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001683", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003591", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003591", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025875", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025875", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036871", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036871", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037904", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037904", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057714", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057714", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:415893", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415893", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WSKNDLC", "url": "https://omabrowser.org/oma/group/WSKNDLC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A6X1", "url": "https://www.orthodb.org/?gene=A0A8V1A6X1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AEL0", "url": "https://www.orthodb.org/?gene=A0A8V1AEL0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15454", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15454", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15454:SF35", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15454:SF35", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00560", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00560", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00787", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00787", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12799", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12799", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25625", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25625", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-9013149", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013149", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9696264", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9696264", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9696270", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9696270", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015148236", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015148236", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1A6X1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6X1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A6X1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6X1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AEL0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEL0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AEL0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEL0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEAAAAAGEDGEEPLRSARVLGSELVETYTVYIIQVSVGNHQWTVKHRYSDFHDLHEKLVSEKKIDKNLLPPKKIIGKNSKSLVEKRQKELEVYLQTLLVKFSVTAPKVLSHFLHFHFYEINGITAALAEELFHKGEQLLMAGEVFTIRPLQLYAVTQQLLQGKPTCANGDAKTDLGHILDFTCRLKYLKVTGTGGPFGTSNIQEHHLPFDLSIFKSLHQIEINHCGGKLIKGLTSSKHTLATMSVRFSATSMKEILVPEASEFDQWEPEGASASCPVTAVIPTWRNLTTLDMSHNNISQIDDSVKLIPKIEFLDLSHNGVSLVENLQHLYNLVHLDLSYNKLTSLEGVHTKLGNIKTLNLAGNQLESLYGLNKLYSLVNLDLSSNRIEQIDEVKNIGSLPCLEKVVLSSNPLSIIPDYRTKVLAQFGDRASEVCLDNIVTTEKELDTVEVLKAIQKSKEVKYKLSNSDKKISEDFRLTAASSKSNCSSLTVRPSSPSLPRPVSSSQEIVCEETVLASSSFQFNASTPTDHTVPQRCSEIPDSRCKNQAPVSLLEYGRGDNTCLDHPEEERCTVPDPCNTVILPFNCMSYTATNQDFTQHLSALIAQTVQRTTPSFIENKGSLPAGSRTTDKEDGYFEMGLHEGDQTFEFSTSQTQSSDNVAVKSINVVKILWSFSIHIYKEVRQFASCLVLTDDLLAVFEIPPQELRGSCQHIPSALKLILCFPYADLTEFGFLMPEICLMLKLKNSDNCLFVVSDSQNLQDFYSCLHTCHSRHCTSVLPSSTTYCGSANLQEFLSQLMELNCISSEDVEIKGCFPTYLVYGNKTNAQKTLHQPDSAGSNKAWSKDDLRSTLYSSMYKSSDQCPCVFHPCWLFLTTQHLYIIKVDFSVLPNKWIGTEDLRSVLKLNSIPLASVVLHPTHGSIQQKGSFLDGHVLELLIGYRFVTAVFVLPHEKFHFLRVYSLLRTLLKNVKTIIVFKASNKSDAARNHVLESNRHGQSASFYKPHLTLSSLYPSEFLIQKITEDNQIPVHLHASVSLQYVAGLKGNALVEFFHGNIAEVENEELRHLMWSSVLFYKTPSVEVMACVLLSTKAIYFLLDDTFNHADEQQSDFWNQENSDCENNSFHLSCCLVLKLNDLQSVNVGLFDQYFRITGQSADHIVTCLTRDSYNTHAFMQQLMAVLSLLARTPSPEPIDKDFYSEFGSKNTGKMENYELIHSSRVKFIYPNEEEIGDLAFLVAEKMDDLTHLQSLHILLYVLAFQVNPVEGSAQNTSPLQPKTLILTSSDLFLFDEDYICYPLPEFAKEPPKRDKYRLADGRRIRDLDRVLMGYQTYPQALTFVFDDVQNQNLMQNLALNHFGDADSAPKGNAKQEGNRSREIQWYIFIPSAESRERLISLLARQWEILCGRELPLELTG", "length": 1416, "header": "tr|A0A8V1A6X1-1|A0A8V1A6X1_CHICK Isoform 1 of Nischarin OS=Gallus gallus OX=9031 GN=NISCH PE=4 SV=1 CANONICAL=A0A8V1A6X1-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A6X1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6X1/entry#A0A8V1A6X1-1", "sequence": { "sequence": "MEAAAAAGEDGEEPLRSARVLGSELVETYTVYIIQVSVGNHQWTVKHRYSDFHDLHEKLVSEKKIDKNLLPPKKIIGKNSKSLVEKRQKELEVYLQTLLVKFSVTAPKVLSHFLHFHFYEINGITAALAEELFHKGEQLLMAGEVFTIRPLQLYAVTQQLLQGKPTCANGDAKTDLGHILDFTCRLKYLKVTGTGGPFGTSNIQEHHLPFDLSIFKSLHQIEINHCGGKLIKGLTSSKHTLATMSVRFSATSMKEILVPEASEFDQWEPEGASASCPVTAVIPTWRNLTTLDMSHNNISQIDDSVKLIPKIEFLDLSHNGVSLVENLQHLYNLVHLDLSYNKLTSLEGVHTKLGNIKTLNLAGNQLESLYGLNKLYSLVNLDLSSNRIEQIDEVKNIGSLPCLEKVVLSSNPLSIIPDYRTKVLAQFGDRASEVCLDNIVTTEKELDTVEVLKAIQKSKEVKYKLSNSDKKISEDFRLTAASSKSNCSSLTVRPSSPSLPRPVSSSQEIVCEETVLASSSFQFNASTPTDHTVPQRCSEIPDSRCKNQAPVSLLEYGRGDNTCLDHPEEERCTVPDPCNTVILPFNCMSYTATNQDFTQHLSALIAQTVQRTTPSFIENKGSLPAGSRTTDKEDGYFEMGLHEGDQTFEFSTSQTQSSDNVAVKSINVVKILWSFSIHIYKEVRQFASCLVLTDDLLAVFEIPPQELRGSCQHIPSALKLILCFPYADLTEFGFLMPEICLMLKLKNSDNCLFVVSDSQNLQDFYSCLHTCHSRHCTSVLPSSTTYCGSANLQEFLSQLMELNCISSEDVEIKGCFPTYLVYGNKTNAQKTLHQPDSAGSNKAWSKDDLRSTLYSSMYKSSDQCPCVFHPCWLFLTTQHLYIIKVDFSVLPNKWIGTEDLRSVLKLNSIPLASVVLHPTHGSIQQKGSFLDGHVLELLIGYRFVTAVFVLPHEKFHFLRVYSLLRTLLKNVKTIIVFKASNKSDAARNHVLESNRHGQSASFYKPHLTLSSLYPSEFLIQKITEDNQIPVHLHASVSLQYVAGLKGNALVEFFHGNIAEVENEELRHLMWSSVLFYKTPSVEVMACVLLSTKAIYFLLDDTFNHADEQQSDFWNQENSDCENNSFHLSCCLVLKLNDLQSVNVGLFDQYFRITGQSADHIVTCLTRDSYNTHAFMQQLMAVLSLLARTPSPEPIDKDFYSEFGSKNTGKMENYELIHSSRVKFIYPNEEEIGDLAFLVAEKMDDLTHLQSLHILLYVLAFQVNPVEGSAQNTSPLQPKTLILTSSDLFLFDEDYICYPLPEFAKEPPKRDKYRLADGRRIRDLDRVLMGYQTYPQALTFVFDDVQNQNLMQNLALNHFGDADSAPKGNAKQEGNRSREIQWYIFIPSAESRERLISLLARQWEILCGRELPLELTG", "length": 1416, "header": "tr|A0A8V1A6X1-1|A0A8V1A6X1_CHICK Isoform 1 of Nischarin OS=Gallus gallus OX=9031 GN=NISCH PE=4 SV=1 CANONICAL=A0A8V1A6X1-1" }, "locus": { "chromosome": "12", "start_pos": 683616, "end_pos": 650049, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067931.1", "url": "https://www.ensembl.org/id/ENSGALT00010067931.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041674.1", "url": "https://www.ensembl.org/id/ENSGALP00010041674.1" } ] } }, { "isoform_ac": "A0A8V1AEL0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6X1/entry#A0A8V1AEL0-1", "sequence": { "sequence": "MLCEFLSLHCSLFQVYIIQVSVGNHQWTVKHRYSDFHDLHEKLVSEKKIDKNLLPPKKIIGKNSKSLVEKRQKELEVYLQTLLVKFSVTAPKVLSHFLHFHFYEINGITAALAEELFHKGEQLLMAGEVFTIRPLQLYAVTQQLLQGKPTCANGDAKTDLGHILDFTCRLKYLKVTGTGGPFGTSNIQEHHLPFDLSIFKSLHQIEINHCGGKLIKGLTSSKHTLATMSVRFSATSMKEILVPEASEFDQWEPEGASASCPVTAVIPTWRNLTTLDMSHNNISQIDDSVKLIPKIEFLDLSHNGVSLVENLQHLYNLVHLDLSYNKLTSLEGVHTKLGNIKTLNLAGNQLESLYGLNKLYSLVNLDLSSNRIEQIDEVKNIGSLPCLEKVVLSSNPLSIIPDYRTKVLAQFGDRASEVCLDNIVTTEKELDTVEVLKAIQKSKEVKYKLSNSDKKISEDFRLTAASSKSNCSSLTVRPSSPSLPRPVSSSQEIVCEETVLASSSFQFNASTPTDHTVPQRCSEIPDSRCKNQAPVSLLEYGRGDNTCLDHPEEERCTVPDPCNTVILPFNCMSYTATNQDFTQHLSALIAQTVQRTTPSFIENKGSLPAGSRTTDKEDGYFEMGLHEGDQTFEFSTSQTQSSDNVAVKSINVVKILWSFSIHIYKEVRQFASCLVLTDDLLAVFEIPPQELRGSCQHIPSALKLILCFPYADLTEFGFLMPEICLMLKLKNSDNCLFVVSDSQNLQDFYSCLHTCHSRHCTSVLPSSTTYCGSANLQEFLSQLMELNCISSEDVEIKGCFPTYLVYGNKTNAQKTLHQPDSAGSNKAWSKDDLRSTLYSSMYKSSDQCPCVFHPCWLFLTTQHLYIIKVDFSVLPNKWIGTEDLRSVLKLNSIPLASVVLHPTHGSIQQKGSFLDGHVLELLIGYRFVTAVFVLPHEKFHFLRVYSLLRTLLKNVKTIIVFKASNKSDAARNHVLESNRHGQSASFYKPHLTLSSLYPSEFLIQKITEDNQIPVHLHASVSLQYVAGLKGNALVEFFHGNIAEVENEELRHLMWSSVLFYKTPSVEVMACVLLSTKAIYFLLDDTFNHADEQQSDFWNQENSDCENNSFHLSCCLVLKLNDLQSVNVGLFDQYFRITGQSADHIVTCLTRDSYNTHAFMQQLMAVLSLLARTPSPEPIDKDFYSEFGSKNTGKMENYELIHSSRVKFIYPNEEEIGDLAFLVAEKMDDLTHLQSLHILLYVLAFQVNPVEGSAQNTSPLQPKTLILTSSDLFLFDEDYICYPLPEFAKEPPKRDKYRLADGRRIRDLDRVLMGYQTYPQALTFVFDDVQNQNLMQNLALNHFGDADSAPKGNAKQEGNRSREIQWYIFIPSAESRERLISLLARQWEILCGRELPLELTG", "length": 1400, "header": "tr|A0A8V1AEL0-1|A0A8V1AEL0_CHICK Computationally mapped isoform of Nischarin OS=Gallus gallus OX=9031 GN=NISCH PE=4 SV=1 CANONICAL=A0A8V1A6X1-1" }, "locus": { "chromosome": "12", "start_pos": 683616, "end_pos": 655243, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067930.1", "url": "https://www.ensembl.org/id/ENSGALT00010067930.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041673.1", "url": "https://www.ensembl.org/id/ENSGALP00010041673.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:415893", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415893", "resource": "KEGG Pathway" }, { "id": "R-GGA-9013149", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013149", "resource": "Reactome", "description": "RAC1 GTPase cycle" }, { "id": "R-GGA-9696264", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9696264", "resource": "Reactome", "description": "RND3 GTPase cycle" }, { "id": "R-GGA-9696270", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9696270", "resource": "Reactome", "description": "RND2 GTPase cycle" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A5G2RKR1-1", "protein_name": "Nischarin", "gene_name": "NISCH", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAAAARSFGPEPEAEPAKEARVVGSELVDTYTVYIIQVTDGSHEWTVKHRYSDFHDLHEKLVAEKKIDKSLLPPKKIIGKNSRSLVEKREKDLEVYLQTLLATFPDVAPRVLAHFLHFHFYEINGITAALAEELFEKGEQLLGAGEVFAIGPLQLYAVTEQLQQGKPTCASGDAKTDLGHILDFTCRLKYLKVSGTEGPFGTSNIQEQHLPFDLSIFKSLHQVEISHCDAKHIRGLVASKPTLATMSVCFSATSMKEVLVPEASEFDEWEPAGAALEGPVTAIIPTWQALTALDLSHNSISEIDESVKLIPKIEFLDLSHNGVLVVDNLQHLYNLVHLDLSYNKLSSLEGVHTKLGNIKTLNLAGNLLGSLHGLHKLYSLVNLDLSNNRIEQMEEVRSIGSLPCLEHVALLNNPLSIIPDYRTKVLAQFGERASEVCLDNTVTTEKELDTVEVLKAIQKAKEVKSKLSNTEKKVSEDSRLSAATCIRPSGSPPTVAPTSASLPQPILSNQGIMFVQEEALASSLSSTDSLTPEDRPIARGCSDSLESIPAGQALCDEIRDVPGAVGGASPEHSEPEVQVVPGSGQIIFLPFTCIGYTATNQDFIQRLSTLIRQAIERQLPAWIEAANQREEGRGEQGEEEEEEEEEDVAENRYFEMGPPDVEEEEEGGPGEEEEEEEEEEEEEGEEGEEERLALEWALGADEDFLLEHIRILKVLWCFLIHVQGSIRQFAACLVLTDFGIAVFEIPHQESRGSSQHILSSLRFVFCFPHGDLTEFGFLMPELCLVLKVRHSENTLFIISDATNLHEFHADLRSCFAPQHMAMLCSPVLYGSHTSLQEFLRQLLTFYKVAGGCQERSQGCFPVYLVYSDKRMVQTAAGDYSGNIEWASCTLCSAVRRSCCAPSEAVKSAAIPYWLLLTPQHLNVIKADFNPMPNRGTHNCRNRNSFKLSRVPLSTVLLDPTRSCTQPRGAFADGHVLELLVGYRFVTAIFVLPHEKFHFLRIYNQLRASLQDLKTVVIAKTPATGGRPQSPLADGQPTEGRASDDQHLQEALEEVPVPALAPAEAPGLAKIPAPAEASEPALVLPEAPTEASASEETPAEASAGASVPAPAEGTAQAEAPAQYPSERLIQSMSEENQIPSHLPACPSLQHIASLQGSAVVEFFHNSIAEVENEELRHLLWSSVVFYQTPGLEVTACVLLSTKAVYFVLHDGLRRYFSEPLQDFWHQKNTDYNNSPFHISQCFVLKLSDLQTVNVGLFDQYFRLTGSSPAQVVTCLTRDSYLTHCFLQHVMAVLSLLERTPSPEPVDKDFYSEFGNKTTGKVENYELIHSSRVKFTYPSEEEIGDLTFTVAQKMADPEKAPGLSILLYVQAFQVGMPLPGRCRGLLRPKTLLLTSAEIFLLDEDFVHYPLPEFAKEPPQRDRYRLDDGRRVRDLDRVLMGYQTYPQALTLVFDDVQGHDLMGSVTLDHFGEEPGGPARAGQGREVQWQVFIPSAESREKLISLLARQWEALCGRELPVELTG", "length": 1520 }, "evidence": [ { "id": "A0A8V1A6X1", "url": "https://omabrowser.org/oma/group/A0A8V1A6X1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1N322-1", "protein_name": "Nischarin", "gene_name": "NISCH", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAAAARSFGPEREAEPVKTARVVGSELVDTYTVYIIQITDGSHEWTVKHRYSDFHDLHEKLVAEKKIDRSLLPPKKIIGKNSRSLVEKREKDLEIYLQTLLATFPDVAPRVLAQFLHFHFYEINGITAALAEELFEKGEQLLGAGEVFAIGPLQLYAVTEQLQQGKPTCASGDAKTDLGHILDFTCRLKYLKVSGTEGPFGTSNIQEQLLPFDLSIFKSLHQVEISHCDARRIRGLVASKPTLATMSVRFSATSMKEVLVPEASEFDEWEPAGAALEGPVTAVIPTWQALTALDLSHNSISEIDDSVKLIPKIEFLDLSHNGVLVMNNLQHLYNLVHVDLSYNKLSSLEGAHTKLGNIKTLNLAGNLLRHLSGLHKLYSLVNLDLSDNRIEQMEEVRSIGSLPCLEHVALLNNPLSIIPDYRTKVLAQFGERASEVCLDNTVTTEKELDTVEVLKAIQKAKEVKSKLSNPEKKVSEDSRLSAAPCVRPSSSPPSAAPTSASLPQPILSNQGIMFVQEDALASSLSSTDSLTPEDRSIVGGCSDSLESIPAGQAPSDDLRDVPGAVGGVSPEHAEPEVQVVPGSGQIIFLPFTCIGYTATNQDFIQRLSTLIRQAIERQLPAWIEAANQREEGQGEQGEDDEEEEDVAENRYFEMGPPDTEEEEEGGPGEEEEEEEEEEAEEERLALEWALGADEDFLLEHIRILKVLWCFLIHVQGSIRQFAACLVLTDFGIAVFEIPHQESRGSSQHILSSLRFVFCFPHGDLTEFGFLMPELCLVLKVRHSENTLFIISDAAHLHEFHADLRACFAPQHMAMLCSPVLYGSHTSLQEFLRQLLTFYKVAGGCQERSQGCFPVYLVYSDKRMVQTAPGDYSGNIEWASCTLCSAVRRSCCAPSEAVKSAAIPYWLLLTPQHLNVIKADFNPMPNRGTHNCRNRNSFKLSRVPLSTVLLDPTRSCTQPRGAFADGHVLELLVGYRFVTAIFVLPHEKFHFLRIYNQLRASLQDLKTVVIAKTPATGGGPQSPLVDGQPAESRASSDQNLQEAPAETTAPALVEAPALTPGEASAPSPAKTPAPVEASVPALVPVEVPEEAEASAEIPVEALAQAEAPAQYPSEPLIRSMSEDNQIPSHLPACPSLRHIASLRGRAVVEFFHSSIAEVENEELRHLLWSSVVFYQMPGLEVTACVLLSTKAVYFVLHDGLRRYFSEPLQDFWHQKNTDYNNSPFHISQCFVLKLSDLQVVNVGLFDQYFRLTGSCPAQVVTCLTRDSYLTHCFLQHLMAVLSLLERTPSPEPVDKDFYSEFGNKTTGKMENYELIHSSRVKFTYPSEEEVGDLTFTVAQKMAAPEKAPALSILLCVQAFQVGSPQPGRCRGLLRPKTLLLTSAEIFLLDEDFVHYPLPEFAKEPPQRDRYRLDDGRRVRDLDRVLMGYQTYPQALTLVFDDVQGHDLMGSVTLDHFGEVPGGPARGGQGREVQWQVFVPSAESREKLISLLARQWEALCGRELPVELTG", "length": 1508 }, "evidence": [ { "id": "A0A8V1A6X1", "url": "https://omabrowser.org/oma/group/A0A8V1A6X1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q4G017-1", "protein_name": "Nischarin", "gene_name": "Nisch", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAATLSFGPEREAEPAKEARVVGSELVDTYTVYVIQVTDGNHEWTIKHRYSDFHDLHEKLVAERKIDKTLLPPKKIIGKNSRSLVEKREKDLEVYLQTLLKTFPDVAPRVLAHFLHFHLYEINGVTAALAEELFEKGEQLLGAGEVFAIRPLQLYAITEQLQQGKPTCASGDAKTDLGHILDFTCRLKYLKVSGTEGPFGTSNIREQLLPFDLSIFKSLHQVEMSHCDAKHVRGLVTSKPTLATMSVRFSAASMKEVLVPEASEFDEWEPEGTTLGGPVTAVIPTWQALTTLDLSHNSISEIDESVKLIPKIEYLDLSHNGVLVVDNLQHLYNLVHLDLSYNKLSSLEGVHTKLGNVKTLNLAGNFLERLSGLHKLYSLVNLDLRDNRIEQLDEVKSIGNLPCLEHVALLNNPLSIIPDYRTKVLSQFGERASEICLDDVATTEKELDTVEVLKAIQKAKDVKSKLSSTEKKVGEDFRLPTAPCIRPSSSPPTAVPTSASLPQPILSNQGIMFVQEEALASSLSSTDSLPPDDRPIAQACSNSMGSLPTGQVAAEDLRDLPGAVGGVSPDHAEPEVQVVPGSGQIIFLPFTCIGYTATNQDFIQRLSTLIRQAIERQLPAWIEAANQREEAHGEQGEEEEEEEEEDVAESRYFEMGPPDAEEEEGSGQGEEDEEDEDEEAEEERLALEWALGADEDFLLEHIRILKVLWCFLIHVQGSIRQFAACLVLTDFGIAVFEIPHQESRGSSQHILSSLRFVFCFPHGDLTEFGFLMPELCLVLKVRHSENTLFIISDAANLHEFHADLRSCFAPQHMAMLCSPILYGSHTSLQEFLRQLLTFYKVAGGSQERSQGCFPVYLVYSDKRMVQTAAGDYSGNIEWASCTLCSAVRRSCCAPSEAVKSAAIPYWLLLTSQHLNVIKADFNPMPSRGTHNCRNRNSFKLSRVPLSTVLLDPTRSCTQPRGAFADGHVLELLVGYRFVTAIFVLPHEKFHFLRVYNQLRASLKDLKTVVIAKNPSARPRTQGPLAGGQPAKSRVSAEQRLQETPAEAPAPAPAAAESAAEAPAAAEASAPAGAPAPAGAPAPAGAPAGAQAPAPAQAEVPAQYPSERLIQSTSEENQIPSHLPVCPSLQHIARLRGRAIIDLFHSSIAEVENEELRHLLWSSVVFYQTPGLEVTACVLLSTKAVYFILHDGLRRYFSEPLQDFWHQKNTDYNNSPFHISQCFVLKLSDLQSVNVGLFDQYFRLTGSSPTQVVTCLTRDSYLTHCFLQHLMLVLSSLERTPSPEPIDKDFYSEFGDKNTGKMENYELIHSSRVKFTYPSEEEVGDLTYVVAQKMADPAKNPALSILLYIQAFQVITPQLGRGRGPLRPKTLLLTSAEIFLLDEDYIHYPLPEFAKEPPQRDRYRLDDGRRVRDLDRVLMGYNPYPQALTLVFDDTQGHDLMGSVTLDHFGEMPGGPGRAGQGREVQWQVFVPSAESREKLISLLARQWEALCGRELPVELTG", "length": 1502 }, "evidence": [ { "id": "A0A8V1A6X1", "url": "https://omabrowser.org/oma/group/A0A8V1A6X1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q80TM9-1", "protein_name": "Nischarin", "gene_name": "Nisch", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAATLSFGPEREAEPAKEARVVGSELVDTYTVYVIQVTDGNHEWTIKHRYSDFHDLHEKLVAERKIDKSLLPPKKIIGKNSRSLVEKRERDLEVYLQTLLTTFPDVAPRVLAHFLHFHLYEVNGVTAALAEELFEKGEQLLGAGEVFAIRPLQLYAITEQLQQGKPTCASGDAKTDLGHILDFTCRLKYLKVSGTEGPFGTSNIKEQLLPFDLSIFKSLHQVEISHCDAKHIRGLVTSKPTLATMSVRFSATSMKEVLAPEASEFDEWEPEGTATLGGPVTAIIPTWQALTTLDLSHNSICEIDESVKLIPKIEYLDLSHNGLRVVDNLQHLYNLVHLDLSYNKLSSLEGVHTKLGNVKTLNLAGNFLESLSGLHKLYSLVNVDLRDNRIEQLDEVKSIGSLPCLERLTLLNNPLSIIPDYRTKVLSQFGERASEICLDDVATTEKELDTVEVLKAIQKAKDVKSKLSNTEKKAGEDFRLPPAPCIRPGGSPPAAPASASLPQPILSNQGIMFVQEEALASSLSSTDSLPPEDHRPIARACSDSLESIPAGQVASDDLRDVPGAVGGVSPDHAEPEVQVVPGSGQIIFLPFTCIGYTATNQDFIQRLSTLIRQAIERQLPAWIEAANQREEAHGEQGEEEEEEEEEEDVAENRYFEMGPPDAEEEEGSGQGEEDEEDEDEEAEEERLALEWALGADEDFLLEHIRILKVLWCFLIHVQGSIRQFAACLVLTDFGIAVFEIPHQESRGSSQHILSSLRFVFCFPHGDLTEFGFLMPELCLVLKVRHSENTLFIISDAANLHEFHADLRSCFAPQHMAMLCSPILYGSHTTLQEFLRQLLTFYKVAGGSQERSQGCFPVYLVYSDKRMVQTPAGDYSGNIEWASCTLCSAVRRSCCAPSEAVKSAAIPYWLLLTSQHLNVIKADFNPMPNRGTHNCRNRNSFKLSRVPLSTVLLDPTRSCTQPRGAFADGHVLELLVGYRFVTAIFVLPHEKFHFLRVYNQLRASLQDLKTVVISKNPSAKPRNQPAKSRASAEQRLQETPADAPAPAAVPPTASAPAPAEALAPDLAPVQAPGEDRGLTSAEAPAAAEAPAAAEAPAAAEAPAAAEAPAAAEAPAAAEAPAPAEAPAAAEAPAAAEAPAAAEAPAAAEAPASAEAPAPNQAPAPARGPAPARGPAPAGGPAPAEALAQAEVPAQYPSERLIQSTSEENQIPSHLPVCPSLQHIARLRGRAIIDLFHNSIAEVENEELRHLLWSSVVFYQTPGLEVTACVLLSSKAVYFILHDGLRRYFSEPLQDFWHQKNTDYNNSPFHVSQCFVLKLSDLQSVNVGLFDQYFRLTGSSPTQVVTCLTRDSYLTHCFLQHLMLVLSSLERTPSPEPVDKDFYSEFGDKNTGKMENYELIHSSRVKFTYPSEEEVGDLTYIVAQKMADPAKNPALSILLYIQAFQVVTPHLGRGRGPLRPKTLLLTSAEIFLLDEDYIHYPLPEFAKEPPQRDRYRLDDGRRVRDLDRVLMGYYPYPQALTLVFDDTQGHDLMGSVTLDHFGEMPGGPGRVGQGREVQWQVFVPSAESREKLISLLARQWEALCGRELPVELTG", "length": 1593 }, "evidence": [ { "id": "A0A8V1A6X1", "url": "https://omabrowser.org/oma/group/A0A8V1A6X1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9Y2I1-1", "protein_name": "Nischarin", "gene_name": "NISCH", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATARTFGPEREAEPAKEARVVGSELVDTYTVYIIQVTDGSHEWTVKHRYSDFHDLHEKLVAERKIDKNLLPPKKIIGKNSRSLVEKREKDLEVYLQKLLAAFPGVTPRVLAHFLHFHFYEINGITAALAEELFEKGEQLLGAGEVFAIGPLQLYAVTEQLQQGKPTCASGDAKTDLGHILDFTCRLKYLKVSGTEGPFGTSNIQEQLLPFDLSIFKSLHQVEISHCDAKHIRGLVASKPTLATLSVRFSATSMKEVLVPEASEFDEWEPEGTTLEGPVTAVIPTWQALTTLDLSHNSVSEIDESVKLIPKIEFLDLSHNGLLVVDNLQHLYNLVHLDLSYNKLSSLEGLHTKLGNIKTLNLAGNLLESLSGLHKLYSLVNLDLRDNRIEQMEEVRSIGSLPCLEHVSLLNNPLSIIPDYRTKVLAQFGERASEVCLDDTVTTEKELDTVEVLKAIQKAKEVKSKLSNPEKKGGEDSRLSAAPCIRPSSSPPTVAPASASLPQPILSNQGIMFVQEEALASSLSSTDSLTPEHQPIAQGCSDSLESIPAGQAASDDLRDVPGAVGGASPEHAEPEVQVVPGSGQIIFLPFTCIGYTATNQDFIQRLSTLIRQAIERQLPAWIEAANQREEGQGEQGEEEDEEEEEEEDVAENRYFEMGPPDVEEEEGGGQGEEEEEEEEDEEAEEERLALEWALGADEDFLLEHIRILKVLWCFLIHVQGSIRQFAACLVLTDFGIAVFEIPHQESRGSSQHILSSLRFVFCFPHGDLTEFGFLMPELCLVLKVRHSENTLFIISDAANLHEFHADLRSCFAPQHMAMLCSPILYGSHTSLQEFLRQLLTFYKVAGGCQERSQGCFPVYLVYSDKRMVQTAAGDYSGNIEWASCTLCSAVRRSCCAPSEAVKSAAIPYWLLLTPQHLNVIKADFNPMPNRGTHNCRNRNSFKLSRVPLSTVLLDPTRSCTQPRGAFADGHVLELLVGYRFVTAIFVLPHEKFHFLRVYNQLRASLQDLKTVVIAKTPGTGGSPQGSFADGQPAERRASNDQRPQEVPAEALAPAPAEVPAPAPAAASASGPAKTPAPAEASTSALVPEETPVEAPAPPPAEAPAQYPSEHLIQATSEENQIPSHLPACPSLRHVASLRGSAIIELFHSSIAEVENEELRHLMWSSVVFYQTPGLEVTACVLLSTKAVYFVLHDGLRRYFSEPLQDFWHQKNTDYNNSPFHISQCFVLKLSDLQSVNVGLFDQHFRLTGSTPMQVVTCLTRDSYLTHCFLQHLMVVLSSLERTPSPEPVDKDFYSEFGNKTTGKMENYELIHSSRVKFTYPSEEEIGDLTFTVAQKMAEPEKAPALSILLYVQAFQVGMPPPGCCRGPLRPKTLLLTSSEIFLLDEDCVHYPLPEFAKEPPQRDRYRLDDGRRVRDLDRVLMGYQTYPQALTLVFDDVQGHDLMGSVTLDHFGEVPGGPARASQGREVQWQVFVPSAESREKLISLLARQWEALCGRELPVELTG", "length": 1504 }, "evidence": [ { "id": "A0A8V1A6X1", "url": "https://omabrowser.org/oma/group/A0A8V1A6X1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "integrin binding", "id": "GO:0005178", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005178", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A6X1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6X1" } ], "pmid": "" }, { "name": "phosphatidylinositol binding", "id": "GO:0035091", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035091", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A6X1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6X1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "early endosome", "id": "GO:0005769", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005769", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A6X1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6X1" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A6X1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6X1" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A6X1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6X1" } ], "pmid": "" }, { "name": "recycling endosome", "id": "GO:0055037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055037", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A6X1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6X1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A6X1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6X1" } ], "pmid": "" }, { "name": "Rac protein signal transduction", "id": "GO:0016601", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016601", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A6X1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6X1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1122, "end_pos": 1124, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1271, "end_pos": 1273, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1374, "end_pos": 1376, "annotation": "n_glycosylation_sequon" }, { "start_pos": 287, "end_pos": 289, "annotation": "n_glycosylation_sequon" }, { "start_pos": 297, "end_pos": 299, "annotation": "n_glycosylation_sequon" }, { "start_pos": 486, "end_pos": 488, "annotation": "n_glycosylation_sequon" }, { "start_pos": 524, "end_pos": 526, "annotation": "n_glycosylation_sequon" }, { "start_pos": 824, "end_pos": 826, "annotation": "n_glycosylation_sequon" }, { "start_pos": 981, "end_pos": 983, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1A6X1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6X1" }, { "id": "PS50195", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50195" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PX", "eco_id": "ECO_0000259", "start_pos": 10, "end_pos": 120, "start_aa": "Asp", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1122, "end_pos": 1124 }, { "start_pos": 1271, "end_pos": 1273 }, { "start_pos": 1374, "end_pos": 1376 }, { "start_pos": 287, "end_pos": 289 }, { "start_pos": 297, "end_pos": 299 }, { "start_pos": 486, "end_pos": 488 }, { "start_pos": 524, "end_pos": 526 }, { "start_pos": 824, "end_pos": 826 }, { "start_pos": 981, "end_pos": 983 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A6Y0-1", "uniprot_ac": "A0A8V1A6Y0", "uniprot_id": "A0A8V1A6Y0_CHICK", "mass": { "chemical_mass": 32078.0, "monoisotopic_mass": 32078.0 }, "refseq": { "ac": "XP_046755403", "name": "uncharacterized protein LOC415758 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046755403" }, "gene_names": [ { "name": "LOC415758", "type": "recommended", "evidence": [ { "id": "A0A8V1A6Y0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6Y0" } ] }, { "name": "LOC415758", "type": "synonym", "evidence": [ { "id": "XP_046755403", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046755403" } ] } ], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "A0A8V1A6Y0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6Y0/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein LOC415758 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_046755403", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046755403" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052542.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_046755403", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046755403" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A6Y0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6Y0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC415758", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6Y0", "locus": {} } ], "crossref": [ { "id": "A0A8V1A6Y0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A6Y0", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd04722", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04722", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "415758", "url": "https://www.ncbi.nlm.nih.gov/gene/415758", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR005137", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005137", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011060", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011060", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A6Y0", "url": "https://www.orthodb.org/?gene=A0A8V1A6Y0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ABY5", "url": "https://www.orthodb.org/?gene=A0A8V1ABY5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21381", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21381", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21381:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21381:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03437", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03437", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_046755403", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046755403", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1A6Y0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6Y0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A6Y0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6Y0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ABY5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABY5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ABY5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABY5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MARPRLFGRLRAAVLGVVHVGALPGTPRSSLPLAQIIDQACQEAEAYKDAGVDGLIVENMHDRPYTLCPGPEVTATMTAVGAAVRRLCPHLALGVQVLCAANQQATAVALAAGLDFIRVEGFVFSHVADEGIINACAGDLLRYRKLVGAENIQIFADIKKKHSAHALTADISVAETASAAELFLADGVVLTGTATGLPADPGELREVQRAVKIPVLIGSGVTLENVKNYLDANALIIASSYSFVPLQTSISNVTNCQVPSSTQGVIMMESFLPELTDKGCFDPLDASSHLENHCCFLSAYVDLQ", "length": 304, "header": "tr|A0A8V1A6Y0-1|A0A8V1A6Y0_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN=LOC415758 PE=3 SV=1 CANONICAL=A0A8V1A6Y0-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A6Y0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6Y0/entry#A0A8V1A6Y0-1", "sequence": { "sequence": "MARPRLFGRLRAAVLGVVHVGALPGTPRSSLPLAQIIDQACQEAEAYKDAGVDGLIVENMHDRPYTLCPGPEVTATMTAVGAAVRRLCPHLALGVQVLCAANQQATAVALAAGLDFIRVEGFVFSHVADEGIINACAGDLLRYRKLVGAENIQIFADIKKKHSAHALTADISVAETASAAELFLADGVVLTGTATGLPADPGELREVQRAVKIPVLIGSGVTLENVKNYLDANALIIASSYSFVPLQTSISNVTNCQVPSSTQGVIMMESFLPELTDKGCFDPLDASSHLENHCCFLSAYVDLQ", "length": 304, "header": "tr|A0A8V1A6Y0-1|A0A8V1A6Y0_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN=LOC415758 PE=3 SV=1 CANONICAL=A0A8V1A6Y0-1" }, "locus": { "chromosome": "11", "start_pos": 8092690, "end_pos": 8065897, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063141.1", "url": "https://www.ensembl.org/id/ENSGALT00010063141.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038977.1", "url": "https://www.ensembl.org/id/ENSGALP00010038977.1" } ] } }, { "isoform_ac": "A0A8V1ABY5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6Y0/entry#A0A8V1ABY5-1", "sequence": { "sequence": "MARPRLFGRLRAAVLGVVHVGALPGTPRSSLPLAQIIDQACQEAEAYKDAGVDGLIVENMHDRPYTLCPGPEVTATMTAVGAAVRRLCPHLALGVQVLCAANQQATAVALAAGLDFIRVEGFVFSHVADEGIINACAGDLLRYRKLVGAENIQIFADIKKKHSAHALTADISVAETASAAELFLADGVVLTGTATGLPADPGELREVQRAVKIPVLIGSGVTLENVKNYLDANALIIASSYSFVPLQTSISNVTNCQVPSSTQGVIMMESFLPELTG", "length": 277, "header": "tr|A0A8V1ABY5-1|A0A8V1ABY5_CHICK Computationally mapped isoform of Uncharacterized protein OS=Gallus gallus OX=9031 GN=LOC415758 PE=3 SV=1 CANONICAL=A0A8V1A6Y0-1" }, "locus": { "chromosome": "11", "start_pos": 8092690, "end_pos": 8067174, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063135.1", "url": "https://www.ensembl.org/id/ENSGALT00010063135.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038974.1", "url": "https://www.ensembl.org/id/ENSGALP00010038974.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 252, "end_pos": 254, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 252, "end_pos": 254 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A6Z8-1", "uniprot_ac": "A0A8V1A6Z8", "uniprot_id": "A0A8V1A6Z8_CHICK", "mass": { "chemical_mass": 64499.0, "monoisotopic_mass": 64499.0 }, "refseq": { "ac": "XP_015148873", "name": "2',5'-phosphodiesterase 12", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015148873" }, "gene_names": [ { "name": "PDE12", "type": "recommended", "evidence": [ { "id": "A0A8V1A6Z8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6Z8" } ] }, { "name": "PDE12", "type": "synonym", "evidence": [ { "id": "XP_015148873", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015148873" } ] } ], "protein_names": [ { "name": "2',5'-phosphodiesterase 12", "type": "recommended", "evidence": [ { "id": "A0A8V1A6Z8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6Z8/entry#names_and_taxonomy" } ] }, { "name": "2',5'-phosphodiesterase 12", "type": "synonym", "evidence": [ { "id": "XP_015148873", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015148873" } ] }, { "name": "Mitochondrial deadenylase", "type": "synonym", "evidence": [ { "id": "A0A8V1A6Z8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6Z8/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052543.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015148873.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015148873", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015148873" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A6Z8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6Z8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PDE12", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6Z8", "locus": { "chromosome": "12", "start_pos": 8900221, "end_pos": 8896004, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027078", "url": "https://www.ensembl.org/id/ENSGALG00010027078" } ] } } ], "crossref": [ { "id": "A0A8V1A6Z8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A6Z8", "database": "AlphaFoldDB", "categories": [] }, { "id": "107054443", "url": "https://www.ncbi.nlm.nih.gov/gene/107054443", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR005135", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005135", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036691", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036691", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048821", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048821", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050410", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050410", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:107054443", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:107054443", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FRLKSAC", "url": "https://omabrowser.org/oma/group/FRLKSAC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A6Z8", "url": "https://www.orthodb.org/?gene=A0A8V1A6Z8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12121", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12121", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12121:SF37", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12121:SF37", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03372", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03372", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21171", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21171", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-8983711", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8983711", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015148873", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015148873", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1A6Z8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6Z8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A6Z8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6Z8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MWRGLRAALGWLSRLGGGGVPPGAMEPAERAVVRCVPSEPKLSLQLVLPDGSARYMQRDQAEPLGRALARLATNAAKGRAKAGKKSKKPRAEDGEAGEAELPEVRLFSRDGRAVSEEVPNAAAWQDGAVLQVGAARYRVERNPPALTELRLPRSLLAGFPVCPKVSAEFAAPQHCLFRWYRERRPRGDGEGPAWEEEREPEGGERVFTPSNALVGLRLKLRCTPGDGTRRFGAPREVESSGPVEAGPGVCTFDARHLYTRKVCGRGSVRAVSYNILADAYAQTEFSRTVLYPYCAPYALEVDYRQNLLKKELAGYNADLICLQEVDKSVFADSLAPALDAFGLEGLFKIKEKQHEGLATFYRRDKFSLLSRHDITFSEALLSEPLHAELRDRLGRYPAVRDKVLQRSSVLQVSVLQSETDPSRKLCVANTHLYWHPKGGNIRLIQIAVALSHIKYVACDLYPNIPLIFCGDFNSTPSSGTYGFINTGGIAEDHEDWASNGEEERCNMPLSHPFKLQSACGEPAYTNYVGGFYGCLDYVFIDQNALEVEQVIPLPSHEEVTTHQALPSVSHPSDHIALVCDLKWK", "length": 584, "header": "tr|A0A8V1A6Z8-1|A0A8V1A6Z8_CHICK Isoform 1 of 2',5'-phosphodiesterase 12 OS=Gallus gallus OX=9031 GN=PDE12 PE=1 SV=1 CANONICAL=A0A8V1A6Z8-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A6Z8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6Z8/entry#A0A8V1A6Z8-1", "sequence": { "sequence": "MWRGLRAALGWLSRLGGGGVPPGAMEPAERAVVRCVPSEPKLSLQLVLPDGSARYMQRDQAEPLGRALARLATNAAKGRAKAGKKSKKPRAEDGEAGEAELPEVRLFSRDGRAVSEEVPNAAAWQDGAVLQVGAARYRVERNPPALTELRLPRSLLAGFPVCPKVSAEFAAPQHCLFRWYRERRPRGDGEGPAWEEEREPEGGERVFTPSNALVGLRLKLRCTPGDGTRRFGAPREVESSGPVEAGPGVCTFDARHLYTRKVCGRGSVRAVSYNILADAYAQTEFSRTVLYPYCAPYALEVDYRQNLLKKELAGYNADLICLQEVDKSVFADSLAPALDAFGLEGLFKIKEKQHEGLATFYRRDKFSLLSRHDITFSEALLSEPLHAELRDRLGRYPAVRDKVLQRSSVLQVSVLQSETDPSRKLCVANTHLYWHPKGGNIRLIQIAVALSHIKYVACDLYPNIPLIFCGDFNSTPSSGTYGFINTGGIAEDHEDWASNGEEERCNMPLSHPFKLQSACGEPAYTNYVGGFYGCLDYVFIDQNALEVEQVIPLPSHEEVTTHQALPSVSHPSDHIALVCDLKWK", "length": 584, "header": "tr|A0A8V1A6Z8-1|A0A8V1A6Z8_CHICK Isoform 1 of 2',5'-phosphodiesterase 12 OS=Gallus gallus OX=9031 GN=PDE12 PE=1 SV=1 CANONICAL=A0A8V1A6Z8-1" }, "locus": { "chromosome": "12", "start_pos": 8899423, "end_pos": 8896017, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065629.1", "url": "https://www.ensembl.org/id/ENSGALT00010065629.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039895.1", "url": "https://www.ensembl.org/id/ENSGALP00010039895.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:107054443", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:107054443", "resource": "KEGG Pathway" }, { "id": "R-GGA-8983711", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8983711", "resource": "Reactome", "description": "OAS antiviral response" } ], "orthologs": [ { "uniprot_canonical_ac": "F1SGK9-1", "protein_name": "2',5'-phosphodiesterase 12", "gene_name": "PDE12", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MWRLPGARAALRGVRTAVERHSRAEAATETAAGVMERAVVRCVPSEPKLSLSFALADGSHKNMQRDQSEPLGRALSRIATNALKGHAKAAAARKSRKNRPNAGGGGACAGSGPEPAAACEPVVKLYYREEAVAEDVLNVDAWQDGAVLQIGDVKYKVERNPPSLTELQLPRYIMAGFPVCPKLGLEFGDPAGSLFRWYKETKPTAVEPEGGGPSSLSPSSPSPGWTETGVNERVYTPSNADIGLRLKLHCTPGNGQRFGPSRELESVCSVEAGPGTCTFDHRHLYTKKVTDDALIRTVSYNLLADTYAQTEFSRTVLYPYCAPYALELDYRQNLIQKELTGYNADLICLQEVDRDVFTDSLVPALEAFGLEGVFRIKQHEGLATFYRKSKFSLLSQHDIAFHEALQSDPLHKELLEKLVLYPAAQEKVLQRSSVLQVSVLQSTKDSSKKICVANTHLYWHPKGGYIRLIQMAVALAHIRHVSCDLYPGIPVVFCGDFNSTPSTGMYHFVINGSIPEDHEDWASNGEEERCNMSLTHFFKLKSACGEPAYTNYVGGFHGCLDYIFIDLNTLEVEQVIPLPSHEEVTTHQALPSVSHPSDHIALVCDLKWK", "length": 609 }, "evidence": [ { "id": "A0A8V1A6Z8", "url": "https://omabrowser.org/oma/group/A0A8V1A6Z8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q08DF7-1", "protein_name": "2',5'-phosphodiesterase 12", "gene_name": "PDE12", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MWRLPGVRAALRGVRTAVERRSRTEAASETSVGAMERAVVRCVPSEPKLSLSFALADGSHKNMQRDQSEPLGRALSRIATNALKGHAKVAAAKKSRKNRPNAGSGVACAGPGPEPAAACEPVVKLYYREEAVAEDVLNVDAWQDGAVLQIGDVKYKVERNPPAFTELQLPRYIMAGFPVCPKLGVEFGDPTGSLFRWYKETKPRAAEPEGGGPSSSSPSSPSPGWTETGVDERVYTPSNADIGLRLKLHCTPGNGQRFGPSRELESVCPVEAGPGTCTFDHRHLYTKKVTDDALIRTVSYNILADTYAQTEFSRTVLYPYCAPYALELDYRQNLIQKELTGYNADLICLQEVDRCVFTDSLMPALEAFGLEGVFRIKQHEGLATFYRKSKFSLLSQHDIAFHEALQSDPLHKELLEKLALYPSAQERVLQRSSVVQVSVLQSTKDSSKKICVANTHLYWHPKGGYIRLIQMAVALAHIRHVSCDLYPGIPVIFCGDFNSTPSTGMYHFVINGSIAEDHEDWTSNGEEERCNMSLSHFFKLKSACGEPAYTNYVGGFHGCLDYIFIDLHALEVEQVIPLPSHEEVTTHQALPSVSHPSDHIALVCDLKWK", "length": 609 }, "evidence": [ { "id": "A0A8V1A6Z8", "url": "https://omabrowser.org/oma/group/A0A8V1A6Z8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q3TIU4-1", "protein_name": "2',5'-phosphodiesterase 12", "gene_name": "Pde12", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWRLPGRSALRGVRSVVERRSRAEAGTHEAVRAMERAVVRCVPSEPKLSLSFALADGSHKNMQRDQSEPLGRALSRIATNALKGHAKVAAAKKSRKNRAHSSGGAACEATGPEPVATCEPVVKLYYREEAVAEDVLNVDAWQDGAVLQIGDVKYKVERNPPTFTELQLPRYIMAGFPVCPKLGVEFGDPASSVFRWYKEVKPGAAEPGDSGPASSSHSSQPSAWIETGVDERVYTPCNADIGLRLRLHCTPGNGQRFGPSRELESLCPVEAGPGTCTFDHRHLYTKKVTEDSFIRTVSYNILADTYAQTEFSRTVLYPYCAPYALELDYRQNLIQKELTGYNADLICLQEVDRAVFSDSLVPALEAFGLEGVFRIKQHEGLATFYRKSKFRLLSQHDISFQEALKSDPLHKELLEKLALNPLAQEKVLQRSSVLQISVLQSTTDSSKKICVANTHLYWHPKGGYIRLIQMEVALVHIRHVSRDLYPGIPVIFCGDFNSTPSTGMYHFVISGSIAEDHEDWASNGEEERCSMPLSHCFKLKSACGEPAYTNYVGGFHGCLDYIFIDLNTLEVEQVIPLPSHEEVTTHQALPSVSHPSDHIALVCDLKWK", "length": 608 }, "evidence": [ { "id": "A0A8V1A6Z8", "url": "https://omabrowser.org/oma/group/A0A8V1A6Z8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6AXQ5-1", "protein_name": "2',5'-phosphodiesterase 12", "gene_name": "Pde12", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MWRLPGRAALRGVRSVVEQRSPAEATTHEAVRAMERAVVRCVPSEPKLSLSFALADGSHKNMQRDQSEPLGRALSRIATNALKGHAKVAAAKKSRKNRAHSSGGAACAATGSEPAATCEPVVKLYYREEAVAEDVLNVDAWQDGAVLQIGDVKYKVERNPPAFTELQLPRYIMAGFPVCPKLGLEFGDPASSVFRWYKEVKPGAAEPGDSGLASSSHSLQSSAWIETGVDERVYTPCNADIGLRLKLHCTPGNGQRFGPSRELESVCPVEAGPGTCTFDHRHLYTKKVTEDSFIRTVSYNILADTYAQTEFSRTVLYPYCAPYALELDYRQNLIQKELTGYNADLICLQEVDRAVFSDSLVPALEAFGLEGVFRIKQHEGLATFYRKSKFRLLSQHDISFQEALKSDPLHKELLEKLALNPLAQEKVLQRSSVLQISVLQSTTDSSKKICVANTHLYWHPKGGYIRLIQMAAALVHIRHVSCDLYPGIPVIFCGDFNSTPSTGMYHFVINGSVPEDHEDWASNGEEERCGMSLTHCFKLKSACGEPAYTNYVGGFHGCLDYIFIDLNALEVEQVIPLPSHEEVTTHQALPSVSHPSDHIALVCDLKWK", "length": 608 }, "evidence": [ { "id": "A0A8V1A6Z8", "url": "https://omabrowser.org/oma/group/A0A8V1A6Z8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6L8Q7-1", "protein_name": "2',5'-phosphodiesterase 12", "gene_name": "PDE12", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MWRLPGARAALRVIRTAVEKLSRAEAGSQTAAGAMERAVVRCVPSEPKLSLSFALADGSHKNMQRDQSEPLGRVLSRIATNALKGHAKAAAAKKSRKSRPNASGGAACSGPGPEPAVFCEPVVKLYYREEAVAEDVLNVDAWQDGAVLQIGDVKYKVERNPPAFTELQLPRYIMAGFPVCPKLSLEFGDPASSLFRWYKEAKPGAAEPEVGVPSSLSPSSPSSSWTETDVEERVYTPSNADIGLRLKLHCTPGDGQRFGHSRELESVCVVEAGPGTCTFDHRHLYTKKVTEDALIRTVSYNILADTYAQTEFSRTVLYPYCAPYALELDYRQNLIQKELTGYNADVICLQEVDRAVFSDSLVPALEAFGLEGVFRIKQHEGLATFYRKSKFSLLSQHDISFYEALESDPLHKELLEKLVLYPSAQEKVLQRSSVLQVSVLQSTKDSSKRICVANTHLYWHPKGGYIRLIQMAVALAHIRHVSCDLYPGIPVIFCGDFNSTPSTGMYHFVINGSIPEDHEDWASNGEEERCNMSLTHFFKLKSACGEPAYTNYVGGFHGCLDYIFIDLNALEVEQVIPLPSHEEVTTHQALPSVSHPSDHIALVCDLKWK", "length": 609 }, "evidence": [ { "id": "A0A8V1A6Z8", "url": "https://omabrowser.org/oma/group/A0A8V1A6Z8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8W0Z9-1", "protein_name": "Carbon catabolite repressor protein 4 homolog 1", "gene_name": "CCR4-1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MLSVIRVHLPSEIPIVGCELTPYVLLRRPDKTPSTDDVPESAPLEGHFLKYRWFRVQSDKKVAICSVHPSETATLQCLGCLKSKVPVAKSYHCSTKCFSDAWQHHRVLHERAASAATEGNDEEELPRLNSSGSGSGVLSTSVSLTNGSSSVYPSAITQKTGAGGETLVEVGRSKTYTPMADDICHVLKFECVVVNAETKQNVGLSCTILTSRVIPAPSPSPRRLISISGTDVTGHLDSNGRPLSMGTFTVLSYNILSDTYASSDIYSYCPTWALAWTYRRQNLLREIVKYRADIVCLQEVQNDHFEEFFLPELDKHGYQGLFKRKTNEVFIGNTNTIDGCATFFRRDRFSHVKKYEVEFNKAAQSLTEAIIPVSQKKNALNRLVKDNVALIVVLEAKFGSQAADNPGKRQLLCVANTHVNVPHELKDVKLWQVHTLLKGLEKIAASADIPMLVCGDFNTVPASAPHTLLAVGKVDPLHPDLMVDPLGILRPHSKLTHQLPLVSAYSQFAKMGGNVITEQQRRRLDPASSEPLFTNCTRDFIGTLDYIFYTADTLTVESLLELLDEESLRKDTALPSPEWSSDHIALLAEFRCMPRARRNNIL", "length": 602 }, "evidence": [ { "id": "A0A8V1A6Z8", "url": "https://omabrowser.org/oma/group/A0A8V1A6Z8/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 9, "go_terms": [ { "name": "cellular response to interferon-alpha", "id": "GO:0035457", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035457", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A6Z8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6Z8" } ], "pmid": "" }, { "name": "cellular response to dsRNA", "id": "GO:0071359", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071359", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A6Z8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6Z8" } ], "pmid": "" }, { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A6Z8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6Z8" } ], "pmid": "" }, { "name": "cellular response to type II interferon", "id": "GO:0071346", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071346", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A6Z8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6Z8" } ], "pmid": "" }, { "name": "positive regulation of viral genome replication", "id": "GO:0045070", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045070", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A6Z8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6Z8" } ], "pmid": "" }, { "name": "nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay", "id": "GO:0000288", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000288", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A6Z8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6Z8" } ], "pmid": "" }, { "name": "mitochondrial mRNA catabolic process", "id": "GO:0000958", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000958", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A6Z8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6Z8" } ], "pmid": "" }, { "name": "regulation of mitochondrial mRNA stability", "id": "GO:0044528", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044528", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A6Z8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6Z8" } ], "pmid": "" }, { "name": "antiviral innate immune response", "id": "GO:0140374", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140374", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A6Z8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6Z8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A6Z8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6Z8" } ], "pmid": "" }, { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A6Z8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6Z8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A6Z8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6Z8" } ], "pmid": "" }, { "name": "3'-5'-RNA exonuclease activity", "id": "GO:0000175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000175", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A6Z8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6Z8" } ], "pmid": "" }, { "name": "poly(A)-specific ribonuclease activity", "id": "GO:0004535", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004535", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A6Z8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6Z8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 473, "end_pos": 475, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1A6Z8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6Z8" }, { "id": "PF21171", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21171" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "2',5'-phosphodiesterase 12-like N-terminal", "eco_id": "ECO_0000259", "start_pos": 143, "end_pos": 244, "start_aa": "Pro", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1A6Z8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6Z8" }, { "id": "PF03372", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03372" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Endonuclease/exonuclease/phosphatase", "eco_id": "ECO_0000259", "start_pos": 272, "end_pos": 574, "start_aa": "Ser", "end_aa": "His", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 473, "end_pos": 475 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A723-1", "uniprot_ac": "A0A8V1A723", "uniprot_id": "A0A8V1A723_CHICK", "mass": { "chemical_mass": 39346.0, "monoisotopic_mass": 39346.0 }, "refseq": { "ac": "XP_417963", "name": "kelch domain-containing protein 8A", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417963" }, "gene_names": [ { "name": "KLHDC8A", "type": "recommended", "evidence": [ { "id": "A0A8V1A723", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A723" } ] }, { "name": "KLHDC8A", "type": "synonym", "evidence": [ { "id": "XP_417963", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417963" } ] } ], "protein_names": [ { "name": "Kelch domain containing 8A", "type": "synonym", "evidence": [ { "id": "A0A8V1A723", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A723/entry#names_and_taxonomy" } ] }, { "name": "kelch domain-containing protein 8A", "type": "synonym", "evidence": [ { "id": "XP_417963", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417963" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052557.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Dec 16, 2011 this sequence version replaced XP_417963.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_417963", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417963" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A723", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A723" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "KLHDC8A", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A723", "locus": { "chromosome": "26", "start_pos": 2126001, "end_pos": 2135665, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010025323", "url": "https://www.ensembl.org/id/ENSGALG00010025323" } ] } } ], "crossref": [ { "id": "A0A8V1A723", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A723", "database": "AlphaFoldDB", "categories": [] }, { "id": "419829", "url": "https://www.ncbi.nlm.nih.gov/gene/419829", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006652", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006652", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015915", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015915", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051746", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051746", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:419829", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419829", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FPYPVHH", "url": "https://omabrowser.org/oma/group/FPYPVHH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A723", "url": "https://www.orthodb.org/?gene=A0A8V1A723", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46260", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46260", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46260:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46260:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01344", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01344", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24681", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24681", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_417963", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417963", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1A723", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A723", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A723-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A723-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDADTMEVANTRDFQWKTLSPLPSRRVYSTLVEVGGQVFAIGGCDDNGVPMDCFEVYSPEADQWTSLPPMPTARAGVAVATLGKRIMVIGGVGANQVPLKIVEMYNVDEGKWKKRNSLREAAMGISVTAKDYRVYAAGGMGADLRPHNYLQHYDMLKDIWVSLAAMPTARYAATSFLRGTKIYVLGGRQSKYAINAFEVFDTETRSWTKFPNIPNKRAFSSFVPTEDKLFSLGGLRQGRLYRQPKFMRTVDVFDFEQGGWMKMERSFYLKKRRADFVAGYLKGRVVVAGGLGNQPTVLESAEAFHPEKNKWESLPPMPTPRCACSSIVLRGCLLLAVGGVSQGLSSAVEALCLSDS", "length": 356, "header": "tr|A0A8V1A723-1|A0A8V1A723_CHICK Isoform 1 of Kelch domain containing 8A OS=Gallus gallus OX=9031 GN=KLHDC8A PE=4 SV=1 CANONICAL=A0A8V1A723-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A723-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A723/entry#A0A8V1A723-1", "sequence": { "sequence": "MDADTMEVANTRDFQWKTLSPLPSRRVYSTLVEVGGQVFAIGGCDDNGVPMDCFEVYSPEADQWTSLPPMPTARAGVAVATLGKRIMVIGGVGANQVPLKIVEMYNVDEGKWKKRNSLREAAMGISVTAKDYRVYAAGGMGADLRPHNYLQHYDMLKDIWVSLAAMPTARYAATSFLRGTKIYVLGGRQSKYAINAFEVFDTETRSWTKFPNIPNKRAFSSFVPTEDKLFSLGGLRQGRLYRQPKFMRTVDVFDFEQGGWMKMERSFYLKKRRADFVAGYLKGRVVVAGGLGNQPTVLESAEAFHPEKNKWESLPPMPTPRCACSSIVLRGCLLLAVGGVSQGLSSAVEALCLSDS", "length": 356, "header": "tr|A0A8V1A723-1|A0A8V1A723_CHICK Isoform 1 of Kelch domain containing 8A OS=Gallus gallus OX=9031 GN=KLHDC8A PE=4 SV=1 CANONICAL=A0A8V1A723-1" }, "locus": { "chromosome": "26", "start_pos": 2130325, "end_pos": 2126756, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010061813.1", "url": "https://www.ensembl.org/id/ENSGALT00010061813.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038156.1", "url": "https://www.ensembl.org/id/ENSGALP00010038156.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 319, "start_aa": "Thr", "end_pos": 319, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr319", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:419829", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419829", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A9J7G045-1", "protein_name": "Kelch domain-containing protein 8A", "gene_name": "Klhdc8a", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEVPNVKDFQWKRLAPLPSRRVYCSLLETGGQVYAIGGCDDNGVPMDCFEVYSPEADQWTSLPSLPTARAGVAVTALGKRIMVIGGVGTNQLPLKVVEMYNIDEGKWKKRSVLREAAMGISVTAKDYRVYAAGGMGLDLRPHNYLQHYDMLKDMWVSLAPMPTPRYAATSFLRGSKIYVLGGRQSKYAVNAFEVFDIESRSWTKFPNIPCKRAFSSFVTLDNHLYSLGGLRQGRLYRQPKFLRTMDVFDMEQGGWLKMERSFFLKKRRADFVAGGLSGRVIVAGGLGNQPTVLETAEAFHPEKNKWEALPAMPTPRCACSSIVFKNCLLAVGGVSQGLSDAVEALYVSES", "length": 350 }, "evidence": [ { "id": "A0A8V1A723", "url": "https://omabrowser.org/oma/group/A0A8V1A723/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0AAA9RVP3-1", "protein_name": "Kelch domain containing 8A", "gene_name": "KLHDC8A", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MEVPTVKDFQWKRLAPLPSRRVYCSLLETGGQVYAIGGCDDNGVPMDCFEVYSPEADQWTALPPLPTARAGVAVTALGKRIMVIGGVGASQLPLKVVEMYNIDEGKWKKRSALREAAMGISVTAKDYRVYAAGGMGLDLRPHNHLQHYDMLKDMWVSLAHMPTPRYAATSFLRGSKIYVLGGRQSKYAVNAFEVFDIETRSWTKFPNIPCKRAFSSFVTLDDRLYSLGGLRQGRLYRQPKFLRTMDVFDMEQGGWLKMERSFFLKKRRADFVAGSLSGRVIVAGGLGNQPTVLETAEAFHPGKSRWEALPAMPTPRCACSSLVLRNCLLAVGGVNQGLSDAVEALCVSDS", "length": 350 }, "evidence": [ { "id": "A0A8V1A723", "url": "https://omabrowser.org/oma/group/A0A8V1A723/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F2Z3R0-1", "protein_name": "Kelch domain containing 8A", "gene_name": "Klhdc8a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEVPNVKDFQWKRLAPLPSRRVYCSLLETGGQVYAIGGCDDNGVPMDCFEVYSPEADQWTSLPSLPTARAGVAITALGKRIMVIGGVGTNQLPVKVVEMYNIDEGKWKKRSVLREAAMGISVTAKDYRVYAAGGMGLDLRPHNYLQHYDMLKDMWVSLAPMPTPRYAATSFLRGSKIYVLGGRQSKYAVNAFEVFDIESRSWTKFPNIPCKRAFSSFVTLDNHLYSLGGLRQGRLYRQPKFLRTMDVFDMEQGGWLKMERSFFLKKRRADFVAGGLSGRVIVAGGLGNQPTVLETAEAFHPEKNKWEALPPMPTPRCACSSIVFKNCLLAVGGVSQGLSDAVEALFVSDS", "length": 350 }, "evidence": [ { "id": "A0A8V1A723", "url": "https://omabrowser.org/oma/group/A0A8V1A723/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "I3L9W7-1", "protein_name": "Kelch domain containing 8A", "gene_name": "KLHDC8A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEVPNVKDFQWKRLAPLPSRRVYCSLLETGGQVYAIGGCDDNGVPMDCFEVYSPEADQWTALPPLPTARAGVAVTALGKRIMVIGGVGTSQLPLKVVEMYNIDEGKWKKRSMLREAAMGISVTAKDYRVYAAGGMGLDLRPHNHLQHYDMLKDMWVSLAPMPTPRYAATSFLRGSKIYVLGGRQSKYAVNAFEVFDIETRSWTKFPNIPCKRAFSSFVTLDDRLYSLGGLRQGRLYRQPKFLRTMDVFDMEQGGWLKMERSFFLKKRRADFVAGSVSGRVIVAGGLGNQPTVLETAEAFHPGKNKWEVLPAMPTPRCACSSIVIKNCLLAVGGVNQGLSDAVEALCVSDS", "length": 350 }, "evidence": [ { "id": "A0A8V1A723", "url": "https://omabrowser.org/oma/group/A0A8V1A723/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q8IYD2-1", "protein_name": "Kelch domain-containing protein 8A", "gene_name": "KLHDC8A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEVPNVKDFQWKRLAPLPSRRVYCSLLETGGQVYAIGGCDDNGVPMDCFEVYSPEADQWTALPRLPTARAGVAVTALGKRIMVIGGVGTNQLPLKVVEMYNIDEGKWKKRSMLREAAMGISVTAKDYRVYAAGGMGLDLRPHNHLQHYDMLKDMWVSLAPMPTPRYAATSFLRGSKIYVLGGRQSKYAVNAFEVFDIETRSWTKFPNIPYKRAFSSFVTLDNHLYSLGGLRQGRLYRQPKFLRTMDVFDMEQGGWLKMERSFFLKKRRADFVAGSLSGRVIVAGGLGNQPTVLETAEAFHPGKNKWEILPAMPTPRCACSSIVVKNCLLAVGGVNQGLSDAVEALCVSDS", "length": 350 }, "evidence": [ { "id": "A0A8V1A723", "url": "https://omabrowser.org/oma/group/A0A8V1A723/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q91XA8-1", "protein_name": "Kelch domain-containing protein 8A", "gene_name": "Klhdc8a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEVPNVKDFQWKRLAPLPSRRVYCSLLETGGQVYAIGGCDDNGVPMDCFEVYSPEADQWTSLPSLPTARAGVAITALGKRIMVIGGVGTNQLPVKVVEMYNIDEGKWKKRSVLREAAMGISVTAKDYRVYAAGGMGLDLRPHNYLQHYDMLKDMWVSLAPMPTPRYAATSFLRGSKIYVLGGRQSKYAVNAFEVFDIESRSWTKFPNIPCKRAFSSFVTLDNHLYSLGGLRQGRLYRQPKFLRTMDVFDMEQGGWLKMERSFFLKKRRADFVAGGLSGRVIVAGGLGNQPTVLETAEAFHPEKNKWEALPPMPTPRCACSSIVFKNCLLAVGGVSQGLSDAVEALFVSDS", "length": 350 }, "evidence": [ { "id": "A0A8V1A723", "url": "https://omabrowser.org/oma/group/A0A8V1A723/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 319 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A726-1", "uniprot_ac": "A0A8V1A726", "uniprot_id": "A0A8V1A726_CHICK", "mass": { "chemical_mass": 25927.0, "monoisotopic_mass": 25927.0 }, "refseq": {}, "gene_names": [ { "name": "FAM72A", "type": "recommended", "evidence": [ { "id": "A0A8V1A726", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A726" } ] } ], "protein_names": [ { "name": "Family with sequence similarity 72 member A", "type": "synonym", "evidence": [ { "id": "A0A8V1A726", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A726/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A726", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A726" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FAM72A", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A726", "locus": {} } ], "crossref": [ { "id": "A0A8V1A726", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A726", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR026768", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026768", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A726", "url": "https://www.orthodb.org/?gene=A0A8V1A726", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31841", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31841", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31841:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31841:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14976", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14976", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1A726", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A726", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A726-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A726-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "QQHGRNSPYGGREKARQSRPSIALRASPADSRQSAKHFPFPTQHPLQTPTIARQSCNEQTEGYEAVPTFHLSVVFSDDLLILFEFCWRRHVFKLNLQADPQPTNAVLSSRGMKAVLLADTDTDLYSTDIPPSGTIDFIGSCYFTEICKCKLKNIACLKCGNIVGYHVISPCKPCLLSCNNGHFWMFYSQAVFGINRLDSSGVNVLLWGNLPDLEENTDEDMSCISEEEYIR", "length": 231, "header": "tr|A0A8V1A726-1|A0A8V1A726_CHICK Isoform 1 of Family with sequence similarity 72 member A OS=Gallus gallus OX=9031 GN=FAM72A PE=3 SV=1 CANONICAL=A0A8V1A726-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A726-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A726/entry#A0A8V1A726-1", "sequence": { "sequence": "QQHGRNSPYGGREKARQSRPSIALRASPADSRQSAKHFPFPTQHPLQTPTIARQSCNEQTEGYEAVPTFHLSVVFSDDLLILFEFCWRRHVFKLNLQADPQPTNAVLSSRGMKAVLLADTDTDLYSTDIPPSGTIDFIGSCYFTEICKCKLKNIACLKCGNIVGYHVISPCKPCLLSCNNGHFWMFYSQAVFGINRLDSSGVNVLLWGNLPDLEENTDEDMSCISEEEYIR", "length": 231, "header": "tr|A0A8V1A726-1|A0A8V1A726_CHICK Isoform 1 of Family with sequence similarity 72 member A OS=Gallus gallus OX=9031 GN=FAM72A PE=3 SV=1 CANONICAL=A0A8V1A726-1" }, "locus": { "chromosome": "26", "start_pos": 2426028, "end_pos": 2421043, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065664.1", "url": "https://www.ensembl.org/id/ENSGALT00010065664.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039930.1", "url": "https://www.ensembl.org/id/ENSGALP00010039930.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A726", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A726" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], 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This record is derived from a genomic sequence (NC_052557.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040508962", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040508962" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9V0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9V0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TCP11", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9V0", "locus": {} } ], "crossref": [ { "id": "A0A8V1A9V0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A9V0", "database": "AlphaFoldDB", "categories": [] }, { "id": "419897", "url": "https://www.ncbi.nlm.nih.gov/gene/419897", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR008862", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008862", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A738", "url": "https://www.orthodb.org/?gene=A0A8V1A738", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A9V0", "url": "https://www.orthodb.org/?gene=A0A8V1A9V0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12832", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12832", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12832:SF14", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12832:SF14", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05794", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05794", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040508962", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040508962", "database": 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"categories": [ "Protein" ] }, { "id": "A0A8V1AJ50-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ50-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAFLMKKKKFKFQTSFTLEELTAVPFVNGVLFCKIRLLDGGDFASLSTREEVQENCVRWKKKFTFVCKMSANPATGLLDPCICRVSVRKELKGGKTYSKLGFADLNLAEFAGSGSTVRCCLLEGYDTKNTRQDNSILKVQQLVTIGMSLLSGDPCFKTPPSTAKSITIPGQDSTLQLTCKGEGTTSSNSSSATIGSLRQTKPRATILSSAGVPEEPDQNLSSPEEVFHSGHSRNSSYASQQSKISGYSTEHSRSSSMSDLTHRRNTSTSSSASGGLSMTVECPEGERDHKLEKPPRPPRPALLLDRPSRRKKDSVESHPTRVDDTRIDADDIVEKIMQSQDFTDVSNTEDSNLRLFVSRDGTTTLSGIQLGNRVSSGVYEPVVIETH", "length": 387, "header": "tr|A0A8V1A749-1|A0A8V1A749_CHICK Isoform 1 of Family with sequence similarity 102 member A OS=Gallus gallus OX=9031 GN=FAM102A PE=3 SV=1 CANONICAL=A0A8V1A749-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A749-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A749/entry#A0A8V1A749-1", "sequence": { "sequence": "MAFLMKKKKFKFQTSFTLEELTAVPFVNGVLFCKIRLLDGGDFASLSTREEVQENCVRWKKKFTFVCKMSANPATGLLDPCICRVSVRKELKGGKTYSKLGFADLNLAEFAGSGSTVRCCLLEGYDTKNTRQDNSILKVQQLVTIGMSLLSGDPCFKTPPSTAKSITIPGQDSTLQLTCKGEGTTSSNSSSATIGSLRQTKPRATILSSAGVPEEPDQNLSSPEEVFHSGHSRNSSYASQQSKISGYSTEHSRSSSMSDLTHRRNTSTSSSASGGLSMTVECPEGERDHKLEKPPRPPRPALLLDRPSRRKKDSVESHPTRVDDTRIDADDIVEKIMQSQDFTDVSNTEDSNLRLFVSRDGTTTLSGIQLGNRVSSGVYEPVVIETH", "length": 387, "header": "tr|A0A8V1A749-1|A0A8V1A749_CHICK Isoform 1 of Family with sequence similarity 102 member A OS=Gallus gallus OX=9031 GN=FAM102A PE=3 SV=1 CANONICAL=A0A8V1A749-1" }, "locus": { "chromosome": "17", "start_pos": 5535785, "end_pos": 5507009, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068013.1", "url": "https://www.ensembl.org/id/ENSGALT00010068013.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041756.1", "url": "https://www.ensembl.org/id/ENSGALP00010041756.1" } ] } }, { "isoform_ac": "A0A8V1AHA4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A749/entry#A0A8V1AHA4-1", "sequence": { "sequence": "MAFLMKKKKFKFQTSFTLEELTAVPFVNGVLFCKIRLLDGGDFASLSTREEVQENCVRWKKKFTFVCKMSANPATGLLDPCICRVSVRKELKGGKTYSKLGFADLNLAEFAGSGSTVRCCLLEGYDTKNTRQDNSILKVTIGMSLLSGDPCFKTPPSTAKSITIPGQDSTLQLTCKGEGTTSSNSSSATIGSLRQTKPRATILSSGVPEEPDQNLSSPEEVFHSGHSRNSSYASQQSKISGYSTEHSRSSSMSDLTHRRNTSTSSSASGGLSMTVECPEGERDHKLEKPPRPPRPALLLDRPSRRKKDSVESHPTRVDDTRIDADDIVEKIMQSQDFTDVSNTEDSNLRLFVSRDGTTTLSGIQLGNRRDF", "length": 371, "header": "tr|A0A8V1AHA4-1|A0A8V1A749_CHICK Computationally mapped isoform of Family with sequence similarity 102 member A OS=Gallus gallus OX=9031 GN=FAM102A PE=3 SV=1 CANONICAL=A0A8V1A749-1" }, "locus": { "chromosome": "17", "start_pos": 5534962, "end_pos": 5507009, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068012.1", "url": "https://www.ensembl.org/id/ENSGALT00010068012.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041754.1", "url": "https://www.ensembl.org/id/ENSGALP00010041754.1" } ] } }, { "isoform_ac": "A0A8V1AJ50-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A749/entry#A0A8V1AJ50-1", "sequence": { "sequence": "MAFLMKKKKFKFQTSFTLEELTAVPFVNGVLFCKIRLLDGGDFASLSTREEVQENCVRWKKKFTFVCKMSANPATGLLDPCICRVSVRKLGFADLNLAEFAGSGSTVRCCLLEGYDTKNTRQDNSILKVTIGMSLLSGDPCFKTPPSTAKSITIPGQDSTLQLTCKGEGTTSSNSSSATIGSLRQTKPRATILSSGVPEEPDQNLSSPEEVFHSGHSRNSSYASQQSKISGYSTEHSRSSSMSDLTHRRNTSTSSSASGGLSMTVECPEGERDHKLEKPPRPPRPALLLDRPSRRKKDSVESHPTRVDDTRIDADDIVEKIMQSQDFTDVSNTEDSNLRLFVSRDGTTTLSGIQLGNRVSSGVYEPVVIETH", "length": 372, "header": "tr|A0A8V1AJ50-1|A0A8V1A749_CHICK Computationally mapped isoform of Family with sequence similarity 102 member A OS=Gallus gallus OX=9031 GN=FAM102A PE=3 SV=1 CANONICAL=A0A8V1A749-1" }, "locus": { "chromosome": "17", "start_pos": 5535785, "end_pos": 5507009, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068014.1", "url": "https://www.ensembl.org/id/ENSGALT00010068014.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041757.1", "url": "https://www.ensembl.org/id/ENSGALP00010041757.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A749", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A749" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A749", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A749" } ], "pmid": "" }, { "name": "membrane raft", "id": "GO:0045121", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045121", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A749", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A749" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "positive regulation of osteoclast differentiation", "id": "GO:0045672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045672", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A749", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A749" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 188, "end_pos": 190, "annotation": "n_glycosylation_sequon" }, { "start_pos": 219, "end_pos": 221, "annotation": "n_glycosylation_sequon" }, { "start_pos": 234, "end_pos": 236, "annotation": "n_glycosylation_sequon" }, { "start_pos": 265, "end_pos": 267, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1A749", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A749" }, { "id": "PS51840", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51840" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2 NT-type", "eco_id": "ECO_0000259", "start_pos": 2, "end_pos": 145, "start_aa": "Ala", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 188, "end_pos": 190 }, { "start_pos": 219, "end_pos": 221 }, { "start_pos": 234, "end_pos": 236 }, { "start_pos": 265, "end_pos": 267 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A753-1", "uniprot_ac": "A0A8V1A753", "uniprot_id": "A0A8V1A753_CHICK", "mass": { "chemical_mass": 56658.0, "monoisotopic_mass": 56658.0 }, "refseq": { "ac": "XP_015153825", "name": "RNA-binding protein MEX3A", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015153825" }, "gene_names": [ { "name": "MEX3A", "type": "recommended", "evidence": [ { "id": "A0A8V1A753", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A753" } ] }, { "name": "MEX3A", "type": "synonym", "evidence": [ { "id": "XP_015153825", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015153825" } ] } ], "protein_names": [ { "name": "Mex-3 RNA binding family member A", "type": "synonym", "evidence": [ { "id": "A0A8V1A753", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A753/entry#names_and_taxonomy" } ] }, { "name": "RNA-binding protein MEX3A", "type": "synonym", "evidence": [ { "id": "XP_015153825", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015153825" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052556.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015153825.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015153825", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015153825" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A753", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A753" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MEX3A", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A753", "locus": { "chromosome": "25", "start_pos": 377536, "end_pos": 363884, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028070", "url": "https://www.ensembl.org/id/ENSGALG00010028070" } ] } } ], "crossref": [ { "id": "A0A8V1A753", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A753", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd16518", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16518", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd16720", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16720", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd22423", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22423", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd22424", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22424", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "101747646", "url": "https://www.ncbi.nlm.nih.gov/gene/101747646", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004088", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004088", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036612", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036612", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047226", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047226", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047227", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047227", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047228", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047228", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:101747646", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:101747646", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SMENRYS", "url": "https://omabrowser.org/oma/group/SMENRYS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A753", "url": "https://www.orthodb.org/?gene=A0A8V1A753", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AEV6", "url": "https://www.orthodb.org/?gene=A0A8V1AEV6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23285", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23285", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23285:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23285:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00013", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00013", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13920", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13920", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015153825", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015153825", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1A753", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A753", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A753-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A753-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AEV6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEV6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AEV6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEV6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPSLLVPGIMERNGGFGDLGCFGGSGKDRALLEDDRALQLALDQLCLLGLGEPSSSSSSSAAVLVEDSNNNNNNPPPPPPPQQPPPPNPPPPPQPQPPPPPPPPPPAPKGPSAAGGGAAEPKLCALYKEAELRLKSSSNTTECVPVPSSEHVAEIVGRQGCKIKALRAKTNTYIKTPVRGEEPVFMVTGRREDVAMARREIISAAEHFSMIRASRNKAGTTFGSAPTLPGQVTIRVRVPYRVVGLVVGPKGATIKRIQQQTNTYIITPSRDRDPVFEITGAPGNVERAREEIETHIAVRTGKILEYNNENDFLSSSPDSSMENRYSEAWRVHTPAPGCKPLSTFRQNSLGCIGDCSVDPVYETPRLNDQNDFNYGYLFPNYGVNKQDLYYGVPESGAPMWAGQENTNPVSVLFSKQQRSSSTGAIHPNSHRSPSSSIQEPNLSALPRRSQGEPLQGFSKLGSTAAARTSVSSSRECMVCFESEVTAALVPCGHNLFCMECAVRICERTDPECPVCHAAATQAIRIFS", "length": 527, "header": "tr|A0A8V1A753-1|A0A8V1A753_CHICK Isoform 1 of Mex-3 RNA binding family member A OS=Gallus gallus OX=9031 GN=MEX3A PE=4 SV=1 CANONICAL=A0A8V1A753-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A753-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A753/entry#A0A8V1A753-1", "sequence": { "sequence": "MPSLLVPGIMERNGGFGDLGCFGGSGKDRALLEDDRALQLALDQLCLLGLGEPSSSSSSSAAVLVEDSNNNNNNPPPPPPPQQPPPPNPPPPPQPQPPPPPPPPPPAPKGPSAAGGGAAEPKLCALYKEAELRLKSSSNTTECVPVPSSEHVAEIVGRQGCKIKALRAKTNTYIKTPVRGEEPVFMVTGRREDVAMARREIISAAEHFSMIRASRNKAGTTFGSAPTLPGQVTIRVRVPYRVVGLVVGPKGATIKRIQQQTNTYIITPSRDRDPVFEITGAPGNVERAREEIETHIAVRTGKILEYNNENDFLSSSPDSSMENRYSEAWRVHTPAPGCKPLSTFRQNSLGCIGDCSVDPVYETPRLNDQNDFNYGYLFPNYGVNKQDLYYGVPESGAPMWAGQENTNPVSVLFSKQQRSSSTGAIHPNSHRSPSSSIQEPNLSALPRRSQGEPLQGFSKLGSTAAARTSVSSSRECMVCFESEVTAALVPCGHNLFCMECAVRICERTDPECPVCHAAATQAIRIFS", "length": 527, "header": "tr|A0A8V1A753-1|A0A8V1A753_CHICK Isoform 1 of Mex-3 RNA binding family member A OS=Gallus gallus OX=9031 GN=MEX3A PE=4 SV=1 CANONICAL=A0A8V1A753-1" }, "locus": { "chromosome": "25", "start_pos": 376899, "end_pos": 363962, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068018.1", "url": "https://www.ensembl.org/id/ENSGALT00010068018.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041761.1", "url": "https://www.ensembl.org/id/ENSGALP00010041761.1" } ] } }, { "isoform_ac": "A0A8V1AEV6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A753/entry#A0A8V1AEV6-1", "sequence": { "sequence": "MGASLLLGKVKPSGGPADPRGGALCVPPTACGRSRGTPGGSERSSHPRGDGRRGRRAFRGAHRSGRAVGPMAVADTRCAPAVGGGVSGTALGVGAPLGSGALDPSEFPPGKSAAPRERLRAAPTGGCKIKALRAKTNTYIKTPVRGEEPVFMVTGRREDVAMARREIISAAEHFSMIRASRNKAGTTFGSAPTLPGQVTIRVRVPYRVVGLVVGPKGATIKRIQQQTNTYIITPSRDRDPVFEITGAPGNVERAREEIETHIAVRTGKILEYNNENDFLSSSPDSSMENRYSEAWRVHTPAPGCKPLSTFRQNSLGCIGDCSVDPVYETPRLNDQNDFNYGYLFPNYGVNKQDLYYGVPESGAPMWAGQENTNPVSVLFSKQQRSSSTGAIHPNSHRSPSSSIQEPNLSALPRRSQGEPLQGFSKLGSTAAARTSVSSSRECMVCFESEVTAALVPCGHNLFCMECAVRICERTDPECPVCHAAATQAIRIFS", "length": 493, "header": "tr|A0A8V1AEV6-1|A0A8V1AEV6_CHICK Computationally mapped isoform of Mex-3 RNA binding family member A OS=Gallus gallus OX=9031 GN=MEX3A PE=4 SV=1 CANONICAL=A0A8V1A753-1" }, "locus": { "chromosome": "25", "start_pos": 376899, "end_pos": 368404, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068017.1", "url": "https://www.ensembl.org/id/ENSGALT00010068017.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041760.1", "url": "https://www.ensembl.org/id/ENSGALP00010041760.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:101747646", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:101747646", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A1B0GWR7-1", "protein_name": "Mex-3 RNA binding family member A", "gene_name": "Mex3a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPSLVVSGIMERNGGFGELGCFGGSAKDRGLLEDERALQLALDQLCLLGLGEPPAPTAGEDGGGGGGGAPAQPAAPPQPAPPPPPAAAPAAPSAAPAAQTPQPPTAPKGANDAKLCALYKEAELRLKGSSNTTECVPVPTSEHVAEIVGRQGCKIKALRAKTNTYIKTPVRGEEPVFMVTGRREDVATARREIISAAEHFSMIRASRNKSGAAFGVAPALPGQVTIRVRVPYRVVGLVVGPKGATIKRIQQQTNTYIITPSRDRDPVFEITGAPGNVERAREEIETHIAVRTGKILEYNSDGDFLAGSPDAALDSRYSDAWRVHAPGCKPLSTFRQNSLGCIGECGVDSAFEAPRLGEQGGDFGYGGYLFPGYGVGKQDVYYGVAETSPPLWAGQENATPTSVLFSSASSSSSSAKARAGPPGAHRSPATSAGPEQLTGLPRRPPGEPLQGFSKLGAGGLRSPGGGRDCMVCFESEVTAALVPCGHNLFCMECAVRICERTDPECPVCHITATQAIRIFS", "length": 520 }, "evidence": [ { "id": "A0A8V1A753", "url": "https://omabrowser.org/oma/group/A0A8V1A753/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A1L020-1", "protein_name": "RNA-binding protein MEX3A", "gene_name": "MEX3A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPSLVVSGIMERNGGFGELGCFGGSAKDRGLLEDERALQLALDQLCLLGLGEPPAPTAGEDGGGGGGGAPAQPAAPPQPAPPPPPAAPPAAPTAAPAAQTPQPPTAPKGASDAKLCALYKEAELRLKGSSNTTECVPVPTSEHVAEIVGRQGCKIKALRAKTNTYIKTPVRGEEPVFMVTGRREDVATARREIISAAEHFSMIRASRNKSGAAFGVAPALPGQVTIRVRVPYRVVGLVVGPKGATIKRIQQQTNTYIITPSRDRDPVFEITGAPGNVERAREEIETHIAVRTGKILEYNNENDFLAGSPDAAIDSRYSDAWRVHQPGCKPLSTFRQNSLGCIGECGVDSGFEAPRLGEQGGDFGYGGYLFPGYGVGKQDVYYGVAETSPPLWAGQENATPTSVLFSSASSSSSSSAKARAGPPGAHRSPATSAGPELAGLPRRPPGEPLQGFSKLGGGGLRSPGGGRDCMVCFESEVTAALVPCGHNLFCMECAVRICERTDPECPVCHITATQAIRIFS", "length": 520 }, "evidence": [ { "id": "A0A8V1A753", "url": "https://omabrowser.org/oma/group/A0A8V1A753/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "E1B7I1-1", "protein_name": "Mex-3 RNA binding family member A", "gene_name": "MEX3A", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPSLVVSGIMERNGGFGELGCFGGSAKDRGLLEDERALQLALDQLCLLGLGEPPAPTAGEDGGGGGGGAPAQPAAPPQPAPPPPPAAPPAAPTAAPAAQTPQPPTAPKGASDAKLCALYKEAELRLKGSSNTTECVPVPTSEHVAEIVGRQGCKIKALRAKTNTYIKTPVRGEEPVFMVTGRREDVATARREIISAAEHFSMIRASRNKSGAAFGVAPALPGQVTIRVRVPYRVVGLVVGPKGATIKRIQQQTNTYIITPSRDRDPVFEITGAPGNVERAREEIETHIAVRTGKILEYNNENDFLAGSPDAALDSRYSEAWRVHPSGCKPLSTFRQNSLGCIGECGVDSGFEAPRLGEQGGDFGYGGYLFPGYGVGKQDVYYGVAETSPPLWAGQENATPTSVLFSSASSSSSSSAKARAGPPGAHRSPAASAGPELAGLPRRPPGEPLQGFSKLGGGGLRSPGGGRDCMVCFESEVTAALVPCGHNLFCMECAVRICERTDPECPVCHITATQAIRIFS", "length": 520 }, "evidence": [ { "id": "A0A8V1A753", "url": "https://omabrowser.org/oma/group/A0A8V1A753/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "E7EXM9-1", "protein_name": "RNA-binding protein MEX3A", "gene_name": "mex3a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MPSLLVLAGIMEKNGGYGGDLAGSGFGSEGLLVPPEEEEDDSRALRVALGQLSLLGLGEGEDGAPAGGGGGGGGVQDRSNNNHHNHIQAEPGMLQGKNKLCALYESSPTETKGRGCNITECVPVPSSEHVAEIVGRQGCKIKALRAKTNTYIKTPVRGEEPVFLITGRKEDVALARREIISAAEHFSMLRASRNKFSGSPPAPLPGQTTIQVRVPYRVVGLVVGPKGSTIKRIQQQTCTYIVTPSRDRDPVFEITGSPGNAERAREEIEAHIAFRTGGLHDHNNENDCLGPESGNGGLESRLQQVWGLQGAPRKPLASSYRQNFSDTVVGSSSGGGGGIYSKGDFNNHGSSGDKPSSYFGSEGTQSWGDPDYPKQVAYYAQQRSKSFGGLPLPLTRLSPGLPEPCGTGNSNAVGSPHAQARRAHSEPTAATGAFTGRLPVPDSPPAMSRDCMTCFESKVTAALVPCGHNLFCMECAIRICELNHPECPVCHTLVTQAIRIFS", "length": 502 }, "evidence": [ { "id": "A0A8V1A753", "url": "https://omabrowser.org/oma/group/A0A8V1A753/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1RLQ1-1", "protein_name": "Mex-3 RNA binding family member A", "gene_name": "MEX3A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPSLVVSGIMERNGGFGELGCFGGSAKDRGLLEDERALQLALDQLCLLGLGEPPAPTAGEDGGGGGGGAPAQPAAPPQPAQPPPPAAPPAAPTAAPAAQTPQPPTAPKGASDAKLCALYKEAELRLKGSSNTTECVPVPTSEHVAEIVGRQGCKIKALRAKTNTYIKTPVRGEEPVFMVTGRREDVATARREIISAAEHFSMIRASRNKSGAAFGVAPALPGQVTIRVRVPYRVVGLVVGPKGATIKRIQQQTNTYIITPSRDRDPVFEITGAPGNVERAREEIETHIAVRTGKILEYNNENDFLAGSPDAGLDSRYSEAWRVHPPGCKPLSTFRQNSLGCIGECGVDSGFEAPRLGEQGGDFGYGGYLFPGYGVGKQDVYYGVAETSPPLWAGQENATPTSVLFSSASSSSSSAKARAGPPGAHRSPATSAGPELAGLPRRPPGEPLQGFSKLGGGGLRSPGGGRDCMVCFESEVTAALVPCGHNLFCMECAVRICERTDPECPVCHITATQAIRIFS", "length": 519 }, "evidence": [ { "id": "A0A8V1A753", "url": "https://omabrowser.org/oma/group/A0A8V1A753/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3UYU0-1", "protein_name": "Mex3 RNA binding family member A", "gene_name": "Mex3a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPSLVVSGIMERNGGFGELGCFGGSAKDRGLLEDERALQLALDQLCLLGLGEPPAPTAGEDGGGGGGGAPAQPAAPPQPAPPPPPAAAPAAPSAAPAAQTPQPPTAPKGANDAKLCALYKEAELRLKGSSNTTECVPVPTSEHVAEIVGRQGCKIKALRAKTNTYIKTPVRGEEPVFMVTGRREDVATARREIISAAEHFSMIRASRNKSGAAFGVAPALPGQVTIRVRVPYRVVGLVVGPKGATIKRIQQQTNTYIITPSRDRDPVFEITGAPGNVERAREEIETHIAVRTGKILEYNSDGDFLAGSPDAALDSRYSDAWRVHAPGCKPLSTFRQNSLGCIGECGVDSAFEAPRLSEQGGDFGYSGYLFPGYGVGKQDVYYGVAETSPPLWAGQENATPTSVLFSSASSSSSSAKARAGPPGAHRSPATSAGPEQLTGLPRRPPGEPLQGFSKLGTGGLRSPGSGRDCMVCFESEVTAALVPCGHNLFCMECAVRICERTDPECPVCHITATQAIRIFS", "length": 520 }, "evidence": [ { "id": "A0A8V1A753", "url": "https://omabrowser.org/oma/group/A0A8V1A753/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A753", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A753" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A753", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A753" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A753", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A753" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A753", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A753" } ], "pmid": "" }, { "name": "P-body", "id": "GO:0000932", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000932", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A753", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A753" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A753", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A753" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 139, "end_pos": 141, "annotation": "n_glycosylation_sequon" }, { "start_pos": 441, "end_pos": 443, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1A753", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A753" }, { "id": "PS50089", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50089" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RING-type", "eco_id": "ECO_0000259", "start_pos": 476, "end_pos": 516, "start_aa": "Cys", "end_aa": "His", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 139, "end_pos": 141 }, { "start_pos": 441, "end_pos": 443 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A757-1", "uniprot_ac": "A0A8V1A757", "uniprot_id": "A0A8V1A757_CHICK", "mass": { "chemical_mass": 69604.0, "monoisotopic_mass": 69604.0 }, "refseq": { "ac": "XP_004948993", "name": "uncharacterized protein C19orf44 homolog isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004948993" }, "gene_names": [ { "name": "C19orf44", "type": "recommended", "evidence": [ { "id": "A0A8V1A757", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A757" } ] }, { "name": "C19orf44", "type": "synonym", "evidence": [ { "id": "XP_004948993", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004948993" } ] } ], "protein_names": [ { "name": "Chromosome 19 open reading frame 44", "type": "synonym", "evidence": [ { "id": "A0A8V1A757", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A757/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein C19orf44 homolog isoform X1", "type": "synonym", "evidence": [ { "id": "XP_004948993", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004948993" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052559.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004948993.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004948993", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004948993" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A757", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A757" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "C19orf44", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A757", "locus": { "chromosome": "28", "start_pos": 4775713, "end_pos": 4783952, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027109", "url": "https://www.ensembl.org/id/ENSGALG00010027109" } ] } } ], "crossref": [ { "id": "A0A8V1A757", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A757", "database": "AlphaFoldDB", "categories": [] }, { "id": "420145", "url": "https://www.ncbi.nlm.nih.gov/gene/420145", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR027884", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027884", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040120", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040120", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:420145", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420145", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FKINVMT", "url": "https://omabrowser.org/oma/group/FKINVMT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A757", "url": "https://www.orthodb.org/?gene=A0A8V1A757", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A9Q7", "url": "https://www.orthodb.org/?gene=A0A8V1A9Q7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22409", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22409", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22409:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22409:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15391", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15391", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004948993", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004948993", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1A757", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A757", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A757-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A757-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A9Q7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9Q7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A9Q7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9Q7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAVRVPAGGEQGRGAAPRWTTAASGHCGLPRSCAELRGDGAELEGARRAPLGRSRFLKVRSGEARGHQRGPAARGGEATSALLSAAHARSNSALRKVAQLQSKILDRKKQLELQSTELGRKPLDEDSSSASSLEHHTRGKKYLKGCAAVGRNVAASRGCSEEEESTQSPKRNVTVTQQLGLGTYEKPMREFMENSLEFSSGRENQRCVTTDSRWGGKRETPVAPGTPPPSHKEIPLTEVSAVPSLHSKGSEKNILGGSNLLRPSPASRNRTARHDMRSQSLSSSMKDNTVKMTLLRRGNAKQSQVSNGSGGSEIKSLDDLFSKADDVEDSTSISSNDFRQNILSLDDLASGISEMAELKQQGTDIQISRETNRNPKKDTFLLEKDQTFPKISAEIDATDTSERDTENVTEAEIPEHLEVSADFSRPRQDYPDQDDRTVNSEYSEDFEQSPSTTDKETVSKMSEEHSESYAYSGKDPSSSASSPLLTRERHKRIHRVAVKETAAQTVDLPFTYCWSKTNSSAVLGLPVGNSYVDPVPIASHVISMDTVEALTAYNPSVLVLNAMLKQHLMLTQQFVENIQHLHLSLVESLENEKFHYHTLEEAKEYIKNHRSPPLTIEQAFEEIQRAEEILPSS", "length": 633, "header": "tr|A0A8V1A757-1|A0A8V1A757_CHICK Isoform 1 of Chromosome 19 open reading frame 44 OS=Gallus gallus OX=9031 GN=C19orf44 PE=4 SV=1 CANONICAL=A0A8V1A757-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A757-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A757/entry#A0A8V1A757-1", "sequence": { "sequence": "MAVRVPAGGEQGRGAAPRWTTAASGHCGLPRSCAELRGDGAELEGARRAPLGRSRFLKVRSGEARGHQRGPAARGGEATSALLSAAHARSNSALRKVAQLQSKILDRKKQLELQSTELGRKPLDEDSSSASSLEHHTRGKKYLKGCAAVGRNVAASRGCSEEEESTQSPKRNVTVTQQLGLGTYEKPMREFMENSLEFSSGRENQRCVTTDSRWGGKRETPVAPGTPPPSHKEIPLTEVSAVPSLHSKGSEKNILGGSNLLRPSPASRNRTARHDMRSQSLSSSMKDNTVKMTLLRRGNAKQSQVSNGSGGSEIKSLDDLFSKADDVEDSTSISSNDFRQNILSLDDLASGISEMAELKQQGTDIQISRETNRNPKKDTFLLEKDQTFPKISAEIDATDTSERDTENVTEAEIPEHLEVSADFSRPRQDYPDQDDRTVNSEYSEDFEQSPSTTDKETVSKMSEEHSESYAYSGKDPSSSASSPLLTRERHKRIHRVAVKETAAQTVDLPFTYCWSKTNSSAVLGLPVGNSYVDPVPIASHVISMDTVEALTAYNPSVLVLNAMLKQHLMLTQQFVENIQHLHLSLVESLENEKFHYHTLEEAKEYIKNHRSPPLTIEQAFEEIQRAEEILPSS", "length": 633, "header": "tr|A0A8V1A757-1|A0A8V1A757_CHICK Isoform 1 of Chromosome 19 open reading frame 44 OS=Gallus gallus OX=9031 GN=C19orf44 PE=4 SV=1 CANONICAL=A0A8V1A757-1" }, "locus": { "chromosome": "28", "start_pos": 4783902, "end_pos": 4780218, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065700.1", "url": "https://www.ensembl.org/id/ENSGALT00010065700.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039966.1", "url": "https://www.ensembl.org/id/ENSGALP00010039966.1" } ] } }, { "isoform_ac": "A0A8V1A9Q7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A757/entry#A0A8V1A9Q7-1", "sequence": { "sequence": "MAVRVPAGGEQGRGAAPRWTTAASGHCGLPRSCAELRGDGAELEGARRAPLGRSRFLKVRSGEARGHQRGPAARGGEATSALLSAAHARSNSALRKVAQLQSKILDRKKQLELQSTELGRKPLDEDSSSASSLEHHTRGKKYLKGCAAVGRNVAASRGCSEEEESTQSPKRNVTVTQQLGLGTYEKPMREFMENSLEFSSGRENQRCVTTDSRWGGKRETPVAPGTPPPSHKEIPLTEVSAVPSLHSKGSEKNILGGSNLLRPSPASRNRTARHDMRSQSLSSSMKDNTVKMTLLRRGNAKQSQVSNGSGGSEIKSLDDLFSKADDVEDSTSISSNDFRQNILSLDDLASGISEMAELKQQGTDIQISRETNRNPKKDTFLLEKDQTFPKISAEIDATDTSERDTENVTEAEIPEHLEVSADFSRPRQDYPDQDDRTVNSEYSEDFEQSPSTTDKETVSKMSEEHSESYAYSGKDPSSSASSPLLTRERHKRIHRVAVKETAAQTVDLPFTYCWSKTNSSAVLGLPVGNSYVDPVPIASHVISMDTVEALTAYNPSVLVLNAMLKQHLMLTQQFVENIQHLHLSLVESLENEKFHYHTLEEAKEVFMIEVLYAS", "length": 614, "header": "tr|A0A8V1A9Q7-1|A0A8V1A9Q7_CHICK Computationally mapped isoform of Chromosome 19 open reading frame 44 OS=Gallus gallus OX=9031 GN=C19orf44 PE=4 SV=1 CANONICAL=A0A8V1A757-1" }, "locus": { "chromosome": "28", "start_pos": 4783902, "end_pos": 4780349, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065702.1", "url": "https://www.ensembl.org/id/ENSGALT00010065702.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039968.1", "url": "https://www.ensembl.org/id/ENSGALP00010039968.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:420145", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420145", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 172, "end_pos": 174, "annotation": "n_glycosylation_sequon" }, { "start_pos": 269, "end_pos": 271, "annotation": "n_glycosylation_sequon" }, { "start_pos": 307, "end_pos": 309, "annotation": "n_glycosylation_sequon" }, { "start_pos": 407, "end_pos": 409, "annotation": "n_glycosylation_sequon" }, { "start_pos": 518, "end_pos": 520, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1A757", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A757" }, { "id": "PF15391", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15391" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DUF4614", "eco_id": "ECO_0000259", "start_pos": 440, "end_pos": 611, "start_aa": "Ser", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 172, "end_pos": 174 }, { "start_pos": 269, "end_pos": 271 }, { "start_pos": 307, "end_pos": 309 }, { "start_pos": 407, "end_pos": 409 }, { "start_pos": 518, "end_pos": 520 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A759-1", "uniprot_ac": "A0A8V1A759", "uniprot_id": "A0A8V1A759_CHICK", "mass": { "chemical_mass": 35214.0, "monoisotopic_mass": 35214.0 }, "refseq": { "ac": "XP_040510825", "name": "retinol dehydrogenase 16-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040510825" }, "gene_names": [ { "name": "LOC100859726", "type": "recommended", "evidence": [ { "id": "A0A8V1A759", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A759" } ] }, { "name": "LOC100859726", "type": "synonym", "evidence": [ { "id": "XP_040510825", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040510825" } ] } ], "protein_names": [ { "name": "RDH16 dehydrogenase", "type": "recommended", "evidence": [ { "id": "A0A8V1A759", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A759/entry#names_and_taxonomy" } ] }, { "name": "retinol dehydrogenase 16-like", "type": "synonym", "evidence": [ { "id": "XP_040510825", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040510825" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052565.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040510825", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040510825" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A759", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A759" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC100859726", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A759", "locus": {} } ], "crossref": [ { "id": "A0A8V1A759", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A759", "database": "AlphaFoldDB", "categories": [] }, { "id": "100859726", "url": "https://www.ncbi.nlm.nih.gov/gene/100859726", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002347", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002347", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036291", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036291", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "VDWLVIE", "url": "https://omabrowser.org/oma/group/VDWLVIE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A759", "url": "https://www.orthodb.org/?gene=A0A8V1A759", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR43313", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43313", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR43313:SF11", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43313:SF11", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00106", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00106", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-2453902", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2453902", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_040510825", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040510825", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1A759", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A759", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A759-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A759-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MWLWLLALLGLWLLRRWHRERQTVPGLEEKFVLITGCDSGFGDLLARQLDARGLRVLAGCLTESGAARLRETASSRLQTVLLDVTSSSSIAAAAAWVQERVGERGLWGLVNNAGIAVPAAPNEWLRKEDFVAVLNVNLVGLIEVTLSLLPLVKRARGRVVNVASVMGRLSIFGGGYCPSKFGVEAFSDNLRLEMQHFGVKVSIIEPGYFKTGITNAAALERTLISTWERLSKETKASYGDKYLQDFLASMREMQKKCNPNLSLVTDCMEHALTRCYPRCRYAAGWDAKLLYIPLSYMPSAITDAFFTWLSPKPAQRA", "length": 317, "header": "tr|A0A8V1A759-1|A0A8V1A759_CHICK Isoform 1 of RDH16 dehydrogenase OS=Gallus gallus OX=9031 GN=LOC100859726 PE=3 SV=1 CANONICAL=A0A8V1A759-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A759-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A759/entry#A0A8V1A759-1", "sequence": { "sequence": "MWLWLLALLGLWLLRRWHRERQTVPGLEEKFVLITGCDSGFGDLLARQLDARGLRVLAGCLTESGAARLRETASSRLQTVLLDVTSSSSIAAAAAWVQERVGERGLWGLVNNAGIAVPAAPNEWLRKEDFVAVLNVNLVGLIEVTLSLLPLVKRARGRVVNVASVMGRLSIFGGGYCPSKFGVEAFSDNLRLEMQHFGVKVSIIEPGYFKTGITNAAALERTLISTWERLSKETKASYGDKYLQDFLASMREMQKKCNPNLSLVTDCMEHALTRCYPRCRYAAGWDAKLLYIPLSYMPSAITDAFFTWLSPKPAQRA", "length": 317, "header": "tr|A0A8V1A759-1|A0A8V1A759_CHICK Isoform 1 of RDH16 dehydrogenase OS=Gallus gallus OX=9031 GN=LOC100859726 PE=3 SV=1 CANONICAL=A0A8V1A759-1" }, "locus": { "chromosome": "34", "start_pos": 1569115, "end_pos": 1567656, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063283.1", "url": "https://www.ensembl.org/id/ENSGALT00010063283.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039064.1", "url": "https://www.ensembl.org/id/ENSGALP00010039064.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-2453902", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2453902", "resource": "Reactome", "description": "The canonical retinoid cycle in rods (twilight vision)" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1LTW0-1", "protein_name": "Retinol dehydrogenase 16-like", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MWLYLAVLLGLYYFLRWYRERQVVSHLRDKFVFITGCDSGFGNQLARQLDLKGLRVLAACLMKQGAEQLRNQTSDRLQTVILDVTKTESVAAATEWVKERVGDRGLWGLVNNAGICTPMAPNQWLTKQDFVKILEVNLLGVIDVTLSLLPLVRKARGHVVNVSSVMGRMAVFGGGYSMSKYGVEAFSDSLMKVAVIEPGYFLTDMTQEEVYHENLQTSWDHASPEIQELYGDNFLADFIKASDFLKAPWARNLSLVTNCMEHALTACHPRSRYSAGWDAKFLYLPMSYLPSFLVDLMIYWNYPQPAKAL", "length": 309 }, "evidence": [ { "id": "A0A8V1A759", "url": "https://omabrowser.org/oma/group/A0A8V1A759/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "O54909-1", "protein_name": "Retinol dehydrogenase 16", "gene_name": "Rdh16", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWLYLVALVGLWTLLRFFRVRQVVSHLQDKYVFITGCDSGFGTLLARQLDRRGMRVLAACLTEKGAEELRNKTSDRLETVILDVTKTESIVTATQWVKEHVGNRGLWGLVNNAGISTPSGPNEWMKKQDFAHVLDVNLLGMIEVTLSMLPLVRKARGRVVNVSSVMGRVSLFGGGYCISKYGVEAFSDSLRRELSYFGVKVAIIEPGFFLTGVTSSARLCSNTQMLWDQTSSEIREIYGEKYLASYLKRLNKLDKRCNKDLSGVTDCMEHALTACHPRTRYSAGWDAKLFYLPLSYLPTFLVDALLYWTSLKPEKAL", "length": 317 }, "evidence": [ { "id": "A0A8V1A759", "url": "https://omabrowser.org/oma/group/A0A8V1A759/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "all-trans-retinol dehydrogenase (NAD+) activity", "id": "GO:0004745", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004745", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A759", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A759" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "retinol metabolic process", "id": "GO:0042572", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042572", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A759", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A759" } ], "pmid": "" }, { "name": "steroid metabolic process", "id": "GO:0008202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008202", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A759", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A759" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 260, "end_pos": 262, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], 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} ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A762-1", "uniprot_ac": "A0A8V1A762", "uniprot_id": "A0A8V1A762_CHICK", "mass": { "chemical_mass": 94040.0, "monoisotopic_mass": 94040.0 }, "refseq": {}, "gene_names": [ { "name": "IKBKE", "type": "recommended", "evidence": [ { "id": "A0A8V1A762", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A762" } ] } ], "protein_names": [ { "name": "Inhibitor of nuclear factor kappa B kinase 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"AlphaFoldDB", "categories": [] }, { "id": "IPR000719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017441", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017441", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041309", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041309", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051180", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051180", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A762", "url": "https://www.orthodb.org/?gene=A0A8V1A762", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A9R1", "url": "https://www.orthodb.org/?gene=A0A8V1A9R1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22969", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22969", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22969:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22969:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00069", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00069", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18394", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18394", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18396", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18396", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-4755510", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4755510", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-936440", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-936440", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-936964", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-936964", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9824878", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9824878", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9860927", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9860927", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1A762", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A762", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A762-1", "url": 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"MPRIVPTALCSVLGRGWELRCCRRWGLQGHPQGTEAEAFPPPAAADACRAGFAIPWVSVLQRGGASLHLAALPARTSVHPPLLGCRPRQVPASSGVWQSTEQRRCLPCAEGRAAVTAMQSTPNYLWSTDDLLGQGATACVYKARSKKSGELVAVKVFNKASYLRPQEVQMREFEMLRKLNHKNIVKLFAVEETGSSKQKVLVMEYCSSGSLLSILEDPANAFGLAEPEFLVVLQCVVAGMNHLRENGVVHRDIKPGNIMRLVGEDGQSIYKLTDFGAARELEDDEKFVSVYGTEEYLHPDMYERAVLRKPQQKAYGVTVDLWSIGVTFYHAATGRLPFVPFGGPRRNKETMYKITTEKPPGAIAGVQRQENGSIEWSYELPLTCQLSVGLKDQLVPILANILEVDQEKCWGFDQFLAETNDILHRIVVDVFSLQQASSHRIYIHSYNTTSKFLDAVFKQTDIVPHHQEYFFEGHPYELDPNLQAHNFCRTARHNPLTLLSCAEQPEDVVGVRYKDPALDFPKFVPKVDVVADCSAAKSAVGAVHQALRIAQELRQCQELTVRGLHWVIGNLRSECSRVLEQRRGVHAVLSGLQLMEGKTRGLYEAIPGGSALPALKDVAAVRIRLQRVAEELSQCSHSIFDFQGALDGMVSELVQHGQQAHEDKSIRQIECCLEKMQLIYKQFRKARTCPALGYNEEQIHKLDKVNLGDLARKVLLIFQDKCAQRYQEALVLHGSRMRKVCEIKKQLKRLSNRISTCSVEASECQDCLQLALDKFLQTVVPEKHSLAMVPAVPSPVPLSQMRREMALQMQELLEQMKSVSYDLQFNNSIIERLSGAAPAPGV", "length": 842, "header": "tr|A0A8V1A762-1|A0A8V1A762_CHICK Isoform 1 of Inhibitor of nuclear factor kappa B kinase subunit epsilon OS=Gallus gallus OX=9031 GN=IKBKE PE=4 SV=1 CANONICAL=A0A8V1A762-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A762-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A762/entry#A0A8V1A762-1", "sequence": { "sequence": 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OX=9031 GN=IKBKE PE=4 SV=1 CANONICAL=A0A8V1A762-1" }, "locus": { "chromosome": "26", "start_pos": 2521308, "end_pos": 2510867, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065705.1", "url": "https://www.ensembl.org/id/ENSGALT00010065705.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039971.1", "url": "https://www.ensembl.org/id/ENSGALP00010039971.1" } ] } }, { "isoform_ac": "A0A8V1A9R1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A762/entry#A0A8V1A9R1-1", "sequence": { "sequence": 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OS=Gallus gallus OX=9031 GN=IKBKE PE=4 SV=1 CANONICAL=A0A8V1A762-1" }, "locus": { "chromosome": "26", "start_pos": 2521308, "end_pos": 2511382, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065707.1", "url": "https://www.ensembl.org/id/ENSGALT00010065707.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039973.1", "url": "https://www.ensembl.org/id/ENSGALP00010039973.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-4755510", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4755510", "resource": "Reactome", "description": "SUMOylation of immune response proteins" }, { "id": "R-GGA-936440", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-936440", "resource": "Reactome", "description": "Negative regulators of DDX58/IFIH1 signaling" }, { "id": "R-GGA-936964", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-936964", "resource": "Reactome", "description": "Activation of IRF3, IRF7 mediated by TBK1, IKK\u03b5 (IKBKE)" }, { "id": "R-GGA-9824878", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9824878", "resource": "Reactome", "description": "Regulation of TBK1, IKK\u03b5 (IKBKE)-mediated activation of IRF3, IRF7" }, { "id": "R-GGA-9860927", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9860927", "resource": "Reactome", "description": "Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "K48-linked polyubiquitin modification-dependent protein binding", "id": "GO:0036435", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036435", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A762", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A762" } ], "pmid": "" }, { "name": "IkappaB kinase activity", "id": "GO:0008384", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008384", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A762", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A762" } ], "pmid": "" }, { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A762", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A762" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A762", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A762" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A762", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A762" } ], "pmid": "" }, { "name": "ubiquitin protein ligase binding", "id": "GO:0031625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031625", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A762", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A762" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A762", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A762" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A762", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A762" } ], "pmid": "" }, { "name": "mitochondrial membrane", "id": "GO:0031966", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031966", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A762", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A762" } ], "pmid": "" }, { "name": "PML body", "id": "GO:0016605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016605", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A762", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A762" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 17, "go_terms": [ { "name": "mRNA stabilization", "id": "GO:0048255", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048255", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A762", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A762" } ], "pmid": "" }, { "name": "positive regulation of lipid storage", "id": "GO:0010884", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010884", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A762", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A762" } ], "pmid": "" }, { "name": "positive regulation of canonical NF-kappaB signal transduction", "id": "GO:0043123", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043123", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A762", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A762" } ], "pmid": "" }, { "name": "intrinsic apoptotic signaling pathway in response to DNA damage", "id": "GO:0008630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008630", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A762", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A762" } ], "pmid": "" }, { "name": "activation of innate immune response", "id": "GO:0002218", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002218", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A762", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A762" } ], "pmid": "" }, { "name": "regulation of protein-containing complex assembly", "id": "GO:0043254", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043254", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A762", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A762" } ], "pmid": "" }, { "name": "cellular response to virus", "id": "GO:0098586", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098586", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A762", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A762" } ], "pmid": "" }, { "name": "positive regulation of type I interferon production", "id": "GO:0032481", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032481", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A762", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A762" } ], "pmid": "" }, { "name": "positive regulation of type I interferon-mediated signaling pathway", "id": "GO:0060340", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060340", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A762", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A762" } ], "pmid": "" }, { "name": "gene expression", "id": "GO:0010467", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010467", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A762", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A762" } ], "pmid": "" }, { "name": "response to interferon-beta", "id": "GO:0035456", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035456", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A762", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A762" } ], "pmid": "" }, { "name": "response to type I interferon", "id": "GO:0034340", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034340", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A762", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A762" } ], "pmid": "" }, { "name": "interleukin-17-mediated signaling pathway", "id": "GO:0097400", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097400", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A762", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A762" } ], "pmid": "" }, { "name": "positive regulation of gene expression", "id": "GO:0010628", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010628", "evidence": [ { "database": 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"species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A786", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A786" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ENG", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A786", "locus": { "chromosome": "17", "start_pos": 5568323, "end_pos": 5558454, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028084", "url": "https://www.ensembl.org/id/ENSGALG00010028084" } ] } } ], "crossref": [ { "id": "A0A8V1A786", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A786", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR055356", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055356", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058899", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058899", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A786", "url": "https://www.orthodb.org/?gene=A0A8V1A786", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AC47", "url": "https://www.orthodb.org/?gene=A0A8V1AC47", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14002", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14002", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14002:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14002:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF23344", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23344", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF26060", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26060", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1A786", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A786", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A786-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A786-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AC47", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC47", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AC47-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC47-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MWGSPCHPCIGAAPVFSTWSSPLPTIKPCGVVFGSRMGSWRLNILKACAVIPNTAALCHHPIRGSRAHPLTLSLGAQHWQQNPLPSGETEARAPLTSSPSSPLTPPPPSPGTAPALRSGISSRHGAAPPADPPPPPPPPPPPAEGSRFPAAAARSLRSGLGVAAGMCRRSSPLLPLLLALLGRPDPAPAEHCDLQPVTAEPPITLFYTTSTVLRGCVSNSSTLASHEVHVLSIQWSKTPVPMLNVSITPRDDDCTRPAALILQCTQCLASITLPCQNLLIHTDASLRPKVQGKELPKDAKGHLLEWVQRTYGGITSYSELKDPQRIHLQLGENSNSPQNCIPQKDFDATPHLEAEVLFREVKGCTSSSAQSARAAHIVQLLHKPSLPITEVKLTLNCPRQQQNNQILLLQGPANLTWLLMLNNCSLQFLASGTYKILHFPMDPRKGELLPDTEQGLIAKAFEKNYSIIASYSVIPISPHITLNIHEREVPKKLPVGPTSSAPSPDDVSSSLLFTLSPWKCTDDTMEIVIARSNLEPIKDVVNITLRDISCQAEKNATHFMLHTLLSHCGTSLENHGHANNELVLSLSKGSVLRSVRVAFQCPIPRELFLRLFPTAAFKAPQTELEVNKEVFVQASMHLEDYPADLQLKECYLMAPGMEPLLLVQGNKAQSSSVAMLEEPPSNRARKVWRFRFTYTVPEGRHVPFSATLKCKAGLQNNTIFEKVLEVKVKDVWRLPNNQGLGLSAVLGITFGAFLIGALLTAGLWYIYSHTRPISKLQPVSTTAPASESSSTNHSIGSTQSTPCSTSSMA", "length": 809, "header": "tr|A0A8V1A786-1|A0A8V1A786_CHICK Isoform 1 of Endoglin OS=Gallus gallus OX=9031 GN=ENG PE=1 SV=1 CANONICAL=A0A8V1A786-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A786-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A786/entry#A0A8V1A786-1", "sequence": { "sequence": "MWGSPCHPCIGAAPVFSTWSSPLPTIKPCGVVFGSRMGSWRLNILKACAVIPNTAALCHHPIRGSRAHPLTLSLGAQHWQQNPLPSGETEARAPLTSSPSSPLTPPPPSPGTAPALRSGISSRHGAAPPADPPPPPPPPPPPAEGSRFPAAAARSLRSGLGVAAGMCRRSSPLLPLLLALLGRPDPAPAEHCDLQPVTAEPPITLFYTTSTVLRGCVSNSSTLASHEVHVLSIQWSKTPVPMLNVSITPRDDDCTRPAALILQCTQCLASITLPCQNLLIHTDASLRPKVQGKELPKDAKGHLLEWVQRTYGGITSYSELKDPQRIHLQLGENSNSPQNCIPQKDFDATPHLEAEVLFREVKGCTSSSAQSARAAHIVQLLHKPSLPITEVKLTLNCPRQQQNNQILLLQGPANLTWLLMLNNCSLQFLASGTYKILHFPMDPRKGELLPDTEQGLIAKAFEKNYSIIASYSVIPISPHITLNIHEREVPKKLPVGPTSSAPSPDDVSSSLLFTLSPWKCTDDTMEIVIARSNLEPIKDVVNITLRDISCQAEKNATHFMLHTLLSHCGTSLENHGHANNELVLSLSKGSVLRSVRVAFQCPIPRELFLRLFPTAAFKAPQTELEVNKEVFVQASMHLEDYPADLQLKECYLMAPGMEPLLLVQGNKAQSSSVAMLEEPPSNRARKVWRFRFTYTVPEGRHVPFSATLKCKAGLQNNTIFEKVLEVKVKDVWRLPNNQGLGLSAVLGITFGAFLIGALLTAGLWYIYSHTRPISKLQPVSTTAPASESSSTNHSIGSTQSTPCSTSSMA", "length": 809, "header": "tr|A0A8V1A786-1|A0A8V1A786_CHICK Isoform 1 of Endoglin OS=Gallus gallus OX=9031 GN=ENG PE=1 SV=1 CANONICAL=A0A8V1A786-1" }, "locus": { "chromosome": "17", "start_pos": 5567757, "end_pos": 5558536, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068055.1", "url": "https://www.ensembl.org/id/ENSGALT00010068055.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041798.1", "url": "https://www.ensembl.org/id/ENSGALP00010041798.1" } ] } }, { "isoform_ac": "A0A8V1AC47-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A786/entry#A0A8V1AC47-1", "sequence": { "sequence": "MWGSPCHPCIGAAPVFSTWSSPLPTIKPCGVVFGSRMGSWRLNILKACAVIPNTAALCHHPIRGSRAHPLTLSLGAQHWQQNPLPSGETEARAPLTSSPSSPLTPPPPSPGTAPALRSGISSRHGAAPPADPPPPPPPPPPPAEGSRFPAAAARSLRSGLGVAAGMCRRSSPLLPLLLALLGRPDPAPAEHCDLQPVTAEPPITLFYTTSTVLRGCVSNSSTLASHEVHVLSIQWSKTPVPMLNVSITPRDDDCTRPAALILQCTQCLASITLPCQNLLIHTDASLRPKVQGKELPKDAKGHLLEWVQRTYGGITSYSELKDPQRIHLQLGENSNSPQNCIPQKDFDATPHLEAEVLFREVKGCTSSSAQSARAAHIVQLLHKPSLPITEVKLTLNCPRQQQNNQILLLQGPANLTWLLMLNNCSLQFLASGTYKILHFPMDPRKGELLPDTEQGLIAKAFEKNYSIIASYSVIPISPHITLNIHEREVPKKLPVGPTSSAPSPDDVSSSLLFTLSPWKCTDDTMEIVIARSNLEPIKDVVNITLRDISCQAEKNATHFMLHTLLSHCGTSLENHGHANNEVAFQCPIPRELFLRLFPTAAFKAPQTELEVNKEVFVQASMHLEDYPADLQLKECYLMAPGMEPLLLVQGNKAQSSSVAMLEEPPSNRARKVWRFRFTYTVPEGRHVPFSATLKCKAGLQNNTIFEKVLEVKVKDVWRLPNNQGLGLSAVLGITFGAFLIGALLTAGLWYIYSHTRPISKLQPVSTTAPASESSSTNHSIGSTQSTPCSTSSMA", "length": 794, "header": "tr|A0A8V1AC47-1|A0A8V1AC47_CHICK Computationally mapped isoform of Endoglin OS=Gallus gallus OX=9031 GN=ENG PE=1 SV=1 CANONICAL=A0A8V1A786-1" }, "locus": { "chromosome": "17", 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"gene_names": [ { "name": "ABHD6", "type": "recommended", "evidence": [ { "id": "A0A8V1A9U5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9U5" } ] } ], "protein_names": [ { "name": "acylglycerol lipase", "type": "recommended", "evidence": [ { "id": "A0A8V1A9U5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9U5/entry#names_and_taxonomy" } ] }, { "name": "3.1.1.23", "type": "synonym", "evidence": [ { "id": "A0A8V1A9U5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9U5/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Lipase that preferentially hydrolysis medium-chain saturated monoacylglycerols including 2-arachidonoylglycerol. Through 2-arachidonoylglycerol degradation may regulate endocannabinoid signaling pathways. Also has a lysophosphatidyl lipase activity with a preference for lysophosphatidylglycerol among other lysophospholipids. Also able to degrade bis(monoacylglycero)phosphate (BMP) and constitutes the major enzyme for BMP catabolism. BMP, also known as lysobisphosphatidic acid, is enriched in late endosomes and lysosomes and plays a key role in the formation of intraluminal vesicles and in lipid sorting.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7A6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7A6#function" }, { "database": "UniProtKB", "id": "ARBA00049568", "url": "https://www.uniprot.org/uniprotkb/ARBA00049568#function" }, { "database": "UniProtKB", "id": "A0A8V1AEQ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEQ8#function" }, { "database": "UniProtKB", "id": "A0A8V1A9U5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9U5#function" }, { "database": "UniProtKB", "id": "A0A8V1A7A0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7A0#function" }, { "database": "UniProtKB", "id": "E1C7P7", "url": "https://www.uniprot.org/uniprotkb/E1C7P7#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9U5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9U5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ABHD6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9U5", "locus": { "chromosome": "12", "start_pos": 9134251, "end_pos": 9112864, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027118", "url": "https://www.ensembl.org/id/ENSGALG00010027118" } ] } } ], "crossref": [ { "id": "A0A8V1A9U5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A9U5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000005696", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000005696", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "416009", "url": "https://www.ncbi.nlm.nih.gov/gene/416009", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000073", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000073", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029058", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029058", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050266", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050266", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416009", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416009", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NAMWQYS", "url": "https://omabrowser.org/oma/group/NAMWQYS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A7A0", "url": "https://www.orthodb.org/?gene=A0A8V1A7A0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A7A6", "url": "https://www.orthodb.org/?gene=A0A8V1A7A6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A9U5", "url": "https://www.orthodb.org/?gene=A0A8V1A9U5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AEQ8", "url": "https://www.orthodb.org/?gene=A0A8V1AEQ8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1C7P7", "url": "https://www.orthodb.org/?gene=E1C7P7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR43798", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43798", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR43798:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43798:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00561", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00561", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-426048", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-426048", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "44316", "url": "https://www.rhea-db.org/rhea/44316", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1A7A0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7A0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A7A0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7A0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A7A6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7A6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A7A6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7A6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A9U5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9U5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A9U5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9U5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AEQ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEQ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AEQ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEQ8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C7P7", "url": "https://www.uniprot.org/uniprotkb/E1C7P7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C7P7-1", "url": "https://www.uniprot.org/uniprotkb/E1C7P7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDLDVLNMFVIAGGTLAIPILAFVASFLLWPSALIRIYYWYWRRALGMQVRYVNYDDNYQFCYSYRGRPGYRPSILMLHGFSGHKDMWLSIVKFLPKNLHLVCVDLPGHEGTTRSALDDYSIMGQAKRIHQFVECIKLNKRPFHLVGTSMGGNVAGVYAAQYPEDVCSLTLICPAGLPSFTDSKFVKMLRELKDSERTDRIPLIPSTPEEMADMLKLCSYVRFKVPQQGLVDVRIPHNDFYRKLFLEIVDEKSRHSLHENMNKIKAPTQVIWGKQDQVLDVSGADILASAIPDCHVSILENCGHSVVVERPRKTANLILEFLAMLHSAGNSKKQA", "length": 335, "header": "tr|A0A8V1A9U5-1|A0A8V1A9U5_CHICK Isoform 1 of acylglycerol lipase OS=Gallus gallus OX=9031 GN=ABHD6 PE=1 SV=1 CANONICAL=A0A8V1A9U5-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A7A0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9U5/entry#A0A8V1A7A0-1", "sequence": { "sequence": "MRRMRSFCWSSEPLRPQRAGPVPRGGGGDLYRVGAGRRSSMDLDVLNMFVIAGGTLAIPILAFVASFLLWPSALIRIYYWYWRRALGMQVRYVNYDDNYQFCYSYRGRPGYRPSILMLHGFSGHKDMWLSIVKFLPKNLHLVCVDLPGHEGTTRSALDDYSIMGQAKRIHQFVECIKLNKRPFHLVGTSMGGNVAGVYAAQYPEDVCSLTLICPAGLPSFTDSKFVKMLRELKDSERTDRIPLIPSTPEEMADMLKLCSYVRFKVPQQILQGLVDVRIPHNDFYRKLFLEIVDEKSRHSLHENMNKIKAPTQVIWGKQDQVLDVSGADILASAIPDCHVSILENCGHSVVVERPRKTANLILEFLAMLHSAGNSKKQA", "length": 378, "header": "tr|A0A8V1A7A0-1|A0A8V1A9U5_CHICK Computationally mapped isoform of acylglycerol lipase OS=Gallus gallus OX=9031 GN=ABHD6 PE=1 SV=1 CANONICAL=A0A8V1A9U5-1" }, "locus": { "chromosome": "12", "start_pos": 9133169, "end_pos": 9124357, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065740.1", "url": "https://www.ensembl.org/id/ENSGALT00010065740.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040006.1", "url": "https://www.ensembl.org/id/ENSGALP00010040006.1" } ] } }, { "isoform_ac": "A0A8V1A7A6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9U5/entry#A0A8V1A7A6-1", "sequence": { "sequence": "MKGSLIEPLRPQRAGPVPRGGGGDLYRVGAGRRSSMDLDVLNMFVIAGGTLAIPILAFVASFLLWPSALIRIYYWYWRRALGMQVRYVNYDDNYQFCYSYRGRPGYRPSILMLHGFSGHKDMWLSIVKFLPKNLHLVCVDLPGHEGTTRSALDDYSIMGQAKRIHQFVECIKLNKRPFHLVGTSMGGNVAGVYAAQYPEDVCSLTLICPAGLPSFTDSKFVKMLRELKDSERTDRIPLIPSTPEEMADMLKLCSYVRFKVPQQILQGLVDVRIPHNDFYRKLFLEIVDEKSRHSLHENMNKIKAPTQVIWGKQDQVLDVSGADILASAIPDCHVSILENCGHSVVVERPRKTANLILEFLAMLHSAGNSKKQA", "length": 373, "header": "tr|A0A8V1A7A6-1|A0A8V1A7A6_CHICK Computationally mapped isoform of acylglycerol lipase OS=Gallus gallus OX=9031 GN=ABHD6 PE=1 SV=1 CANONICAL=A0A8V1A9U5-1" }, "locus": { "chromosome": "12", "start_pos": 9133169, "end_pos": 9113063, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065745.1", "url": "https://www.ensembl.org/id/ENSGALT00010065745.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040011.1", "url": "https://www.ensembl.org/id/ENSGALP00010040011.1" } ] } }, { "isoform_ac": "A0A8V1A9U5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9U5/entry#A0A8V1A9U5-1", "sequence": { "sequence": "MDLDVLNMFVIAGGTLAIPILAFVASFLLWPSALIRIYYWYWRRALGMQVRYVNYDDNYQFCYSYRGRPGYRPSILMLHGFSGHKDMWLSIVKFLPKNLHLVCVDLPGHEGTTRSALDDYSIMGQAKRIHQFVECIKLNKRPFHLVGTSMGGNVAGVYAAQYPEDVCSLTLICPAGLPSFTDSKFVKMLRELKDSERTDRIPLIPSTPEEMADMLKLCSYVRFKVPQQGLVDVRIPHNDFYRKLFLEIVDEKSRHSLHENMNKIKAPTQVIWGKQDQVLDVSGADILASAIPDCHVSILENCGHSVVVERPRKTANLILEFLAMLHSAGNSKKQA", "length": 335, "header": "tr|A0A8V1A9U5-1|A0A8V1A9U5_CHICK Isoform 1 of acylglycerol lipase OS=Gallus gallus OX=9031 GN=ABHD6 PE=1 SV=1 CANONICAL=A0A8V1A9U5-1" }, "locus": { "chromosome": "12", "start_pos": 9133169, "end_pos": 9128062, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065742.1", "url": "https://www.ensembl.org/id/ENSGALT00010065742.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040008.1", "url": "https://www.ensembl.org/id/ENSGALP00010040008.1" } ] } }, { "isoform_ac": "A0A8V1AEQ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9U5/entry#A0A8V1AEQ8-1", "sequence": { "sequence": "MEVGAGRRSSMDLDVLNMFVIAGGTLAIPILAFVASFLLWPSALIRIYYWYWRRALGMQVRYVNYDDNYQFCYSYRGRPGYRPSILMLHGFSGHKDMWLSIVKFLPKNLHLVCVDLPGHEGTTRSALDDYSIMGQAKRIHQFVECIKLNKRPFHLVGTSMGGNVAGVYAAQYPEDVCSLTLICPAGLPSFTDSKFVKMLRELKDSERTDRIPLIPSTPEEMADMLKLCSYVRFKVPQQILQGLVDVRIPHNDFYRKLFLEIVDEKSRHSLHENMNKIKAPTQVIWGKQDQVLDVSGADILASAIPDCHVSILENCGHSVVVERPRKTANLILEFLAMLHSAGNSKKQA", "length": 348, "header": "tr|A0A8V1AEQ8-1|A0A8V1AEQ8_CHICK Computationally mapped isoform of acylglycerol lipase OS=Gallus gallus OX=9031 GN=ABHD6 PE=1 SV=1 CANONICAL=A0A8V1A9U5-1" }, "locus": { "chromosome": "12", "start_pos": 9133169, "end_pos": 9127409, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065739.1", "url": "https://www.ensembl.org/id/ENSGALT00010065739.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040005.1", "url": "https://www.ensembl.org/id/ENSGALP00010040005.1" } ] } }, { "isoform_ac": "E1C7P7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9U5/entry#E1C7P7-1", "sequence": { "sequence": "MDLDVLNMFVIAGGTLAIPILAFVASFLLWPSALIRIYYWYWRRALGMQVRYVNYDDNYQFCYSYRGRPGYRPSILMLHGFSGHKDMWLSIVKFLPKNLHLVCVDLPGHEGTTRSALDDYSIMGQAKRIHQFVECIKLNKRPFHLVGTSMGGNVAGVYAAQYPEDVCSLTLICPAGLPSFTDSKFVKMLRELKDSERTDRIPLIPSTPEEMADMLKLCSYVRFKVPQQILQGLVDVRIPHNDFYRKLFLEIVDEKSRHSLHENMNKIKAPTQVIWGKQDQVLDVSGADILASAIPDCHVSILENCGHSVVVERPRKTANLILEFLAMLHSAGNSKKQA", "length": 338, "header": "tr|E1C7P7-1|A0A8V1A9U5_CHICK Computationally mapped isoform of acylglycerol lipase OS=Gallus gallus OX=9031 GN=ABHD6 PE=1 SV=1 CANONICAL=A0A8V1A9U5-1" }, "locus": { "chromosome": "12", "start_pos": 9133169, "end_pos": 9128062, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065743.1", "url": "https://www.ensembl.org/id/ENSGALT00010065743.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040009.1", "url": "https://www.ensembl.org/id/ENSGALP00010040009.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:416009", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416009", "resource": "KEGG Pathway" }, { "id": "R-GGA-426048", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-426048", "resource": "Reactome", "description": "Arachidonate production from DAG" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287A2V4-1", "protein_name": "Monoacylglycerol lipase ABHD6", "gene_name": "ABHD6", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDLDVVNMFVIAGGTLAIPILAFVASFLLWPSALIRIYYWYWRRALGMQVRYVHHEDYQFCYSFRGRPGHKPSILMLHGFSAHKDMWLSVVKFLPKNLHLICVDMPGHEGTTRSSLDDLSIDGQVKRIHQFVECLKLNRKPFHLIGTSMGGHVAGVYAAYYPSDLCSLSLVCPAGLQYSTDNHFVKQLKELQESAAIEKIPLIPSTPEEMSEMLQLCSYARIKVPQQILQGLVDVRIPHNNFYRKLFLEMVSEKSRYCLHQNMDKIKVPTQIIWGKEDQILDVSGADMLAKSITNCHVDLLENCGHSVVMERPRKTAKLVIDFLTSVHNTDNNKKLD", "length": 337 }, "evidence": [ { "id": "A0A8V1A9U5", "url": "https://omabrowser.org/oma/group/A0A8V1A9U5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A9J7F095-1", "protein_name": "Monoacylglycerol lipase ABHD6", "gene_name": "Abhd6", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MKMGPKYKPPFLFHFPALSKESPFQLLPKPVTFRKSLLLEDLCRCQPPLTSRMDLDVVNMFVIAGGTLAIPILAFVASFLLWPSALIRIYYWYWRRTLGMQVRYAHHEDYQFCYSFRGRPGHKPSILMLHGFSAHKDMWLSVVKFLPKNLHLVCVDMPGHEGTTRSSLDDLSIDGQVKRVHQFVECLKLNKKPFHLIGTSMGGHVAGVYAAYYPSDICSLCLVCPAGLQYSTDNQFVQRLKELQDSAAIQKIPLIPSTPEEMSEMLQLCSYVRFKVPQQILQGLVDVRIPHNSFYRRLFLEIVSEKSRYSLHQNMDKIKVPTQIIWGKQDQVLDVSGADILAKSIANCQVELLENCGHSVVMERPRKTAKLIVDFLASVHNTDNNKKLN", "length": 389 }, "evidence": [ { "id": "A0A8V1A9U5", "url": "https://omabrowser.org/oma/group/A0A8V1A9U5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "E7F881-1", "protein_name": "acylglycerol lipase", "gene_name": "abhd6a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDLDVLNMFLIAGGTLAIPILAFVASFLLWPATLIKVYHWYWRRRLGMQVDYAEYEGYRFCYSHRGNPGFRPSVLMLHGFSAHKDMWLGVVKFLPKNVHLICVDMPGHEGTSRTSAVDYSIEGQVKRINQFVKSIGLNKKPFHLIGTSMGGNVAGVYAARHPSELCGVTLICPAGLQYPTESKFVERLRELEKTQDRDGIPLIPSTPEQMEEMLKLCSYVRFKIPKQILQGLVDVRIPNNDFYHECFMELVGEKSRHSLHENMHLISTPLQVIWGKNDQVLDVSGASVLSGAVPGCQVHLLDNCGHSVVLERPRKSAQLITDFIIAQQNAGINSNKKLS", "length": 339 }, "evidence": [ { "id": "A0A8V1A9U5", "url": "https://omabrowser.org/oma/group/A0A8V1A9U5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q1LZ86-1", "protein_name": "Monoacylglycerol lipase ABHD6", "gene_name": "ABHD6", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MDLDVVNMFVIAGGTLALPILAFVASFLLWPSALIRIYYWYWRRTLGMQVRYVRHEDYQFCYSFRGRPGHKPSILMLHGFSAHKDMWLSMVKFLPKNLHLVCVDMPGHEGTTRSSLDDLSIDGQVKRIHQFVECLKLNKKPFHLVGTSMGGHVAGVYAAHYPSDVCSLSLVCPAGLQYSTDNKFVQRLKELQESAAVEKIPLIPTTPKEMSEMLQLCSYVRFKVPQQILQGLVDVRIPHNTFYRKLFLEIVSEKSRYSLHQNMDKIKVPTQIIWGKQDQVLDVSGADMLAKSIANSQVELLENCGHSVVMERPRKTAKLLVDFLASVHSTDNSKKLD", "length": 337 }, "evidence": [ { "id": "A0A8V1A9U5", "url": "https://omabrowser.org/oma/group/A0A8V1A9U5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q5XI64-1", "protein_name": "Monoacylglycerol lipase ABHD6", "gene_name": "Abhd6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDLDVVNMFVIAGGTLAIPILAFVASFLLWPSALIRIYYWYWRRTLGMQVRYVHHEDYQFCYSFRGRPGHKPSVLMLHGFSAHKDMWLSVVKFLPKNLHLVCVDMPGHEGTTRSSLDDLSIVGQVKRIHQFVECLKLNKKPFHLIGTSMGGNVAGVYAAYYPSDVCSLSLVCPAGLQYSTDNRFVQRLKELEDSAATQKIPLIPSTPEEMSEMLQLCSYVRFKVPQQILQGLVDVRIPHNSFYRKLFLEIVSEKSRYSLHENMDKIKVPTQIIWGKQDQVLDVSGADILAKSITNSQVEVLENCGHSVVMERPRKTAKLVVDFLASVHNPDNNKKLN", "length": 337 }, "evidence": [ { "id": "A0A8V1A9U5", "url": "https://omabrowser.org/oma/group/A0A8V1A9U5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8R2Y0-1", "protein_name": "Monoacylglycerol lipase ABHD6", "gene_name": "Abhd6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDLDVVNMFVIAGGTLAIPILAFVASFLLWPSALIRIYYWYWRRTLGMQVRYAHHEDYQFCYSFRGRPGHKPSILMLHGFSAHKDMWLSVVKFLPKNLHLVCVDMPGHEGTTRSSLDDLSIVGQVKRIHQFVECLKLNKKPFHLIGTSMGGHVAGVYAAYYPSDVCSLSLVCPAGLQYSTDNPFVQRLKELEESAAIQKIPLIPSTPEEMSEMLQLCSYVRFKVPQQILQGLVDVRIPHNSFYRKLFLEIVNEKSRYSLHENMDKIKVPTQIIWGKQDQVLDVSGADILAKSISNSQVEVLENCGHSVVMERPRKTAKLIVDFLASVHNTDNKKLN", "length": 336 }, "evidence": [ { "id": "A0A8V1A9U5", "url": "https://omabrowser.org/oma/group/A0A8V1A9U5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9BV23-1", "protein_name": "Monoacylglycerol lipase ABHD6", "gene_name": "ABHD6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDLDVVNMFVIAGGTLAIPILAFVASFLLWPSALIRIYYWYWRRTLGMQVRYVHHEDYQFCYSFRGRPGHKPSILMLHGFSAHKDMWLSVVKFLPKNLHLVCVDMPGHEGTTRSSLDDLSIDGQVKRIHQFVECLKLNKKPFHLVGTSMGGQVAGVYAAYYPSDVSSLCLVCPAGLQYSTDNQFVQRLKELQGSAAVEKIPLIPSTPEEMSEMLQLCSYVRFKVPQQILQGLVDVRIPHNNFYRKLFLEIVSEKSRYSLHQNMDKIKVPTQIIWGKQDQVLDVSGADMLAKSIANCQVELLENCGHSVVMERPRKTAKLIIDFLASVHNTDNNKKLD", "length": 337 }, "evidence": [ { "id": "A0A8V1A9U5", "url": "https://omabrowser.org/oma/group/A0A8V1A9U5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9U5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9U5" } ], "pmid": "" }, { "name": "mitochondrial membrane", "id": "GO:0031966", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031966", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9U5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9U5" } ], "pmid": "" }, { "name": "lysosomal membrane", "id": "GO:0005765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005765", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9U5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9U5" } ], "pmid": "" }, { "name": "late endosome membrane", "id": "GO:0031902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031902", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9U5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9U5" } ], "pmid": "" }, { "name": "AMPA glutamate receptor complex", "id": "GO:0032281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032281", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9U5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9U5" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9U5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9U5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "acylglycerol catabolic process", "id": "GO:0046464", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046464", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9U5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9U5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "monoacylglycerol lipase activity", "id": "GO:0047372", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047372", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9U5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9U5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "44316", "name": "", "equation": "1-dodecanoylglycerol + H2O = dodecanoate + glycerol + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q5ZIN0-1", "A0A8V1A9U5-1" ], "evidence": [ { "id": "44316", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/44316" } ] }, { "id": "R-GGA-5694462", "name": "ABHD6,12 hydrolyse 3AG", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [ "R-ALL-5694509" ], "output_participant_list": [ "R-ALL-422506" ], "enzyme_list": [ "A0A8V0Z6A2-1", "A0A8V1A9U5-1" ], "evidence": [ { "id": "R-GGA-5694462", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5694462" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-422506", "participant_name": "AA [plasma membrane]", "crossref": [ { "id": "ZINC000004474696", "database": "ZINC", "url": "" }, { "id": "32395", "database": "ChEBI", "url": "" }, { "id": "C00219", "database": "COMPOUND", "url": "" } ] }, { "participant_id": "R-ALL-5694509", "participant_name": "3AG [plasma membrane]", "crossref": [ { "id": "75571", "database": "ChEBI", "url": "" }, { "id": "ZINC000004654970", "database": "ZINC", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0Z6A2", "gene_name": "ABHD12", "activity": [ { "ec_number": "3.1.1.23", "activity": "Hydrolyzes glycerol monoesters of long-chain fatty acids.", "evidence": [ { "id": "A0A8V0Z6A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6A2" } ] }, { "ec_number": "3.1.1.23", "activity": "", "evidence": [ { "id": "A0A8V0Z6A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6A2" } ] } ] }, { "uniprot_ac": "A0A8V1A9U5", "gene_name": "ABHD6", "activity": [ { "ec_number": "3.1.1.23", "activity": "Hydrolyzes glycerol monoesters of long-chain fatty acids.", "evidence": [ { "id": "A0A8V1A9U5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9U5" } ] }, { "ec_number": "3.1.1.23", "activity": "", "evidence": [ { "id": "A0A8V1A9U5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9U5" } ] } ] }, { "uniprot_ac": "Q5ZIN0", "gene_name": "ABHD12", "activity": [ { "ec_number": "3.1.1.-", "activity": "", "evidence": [ { "id": "Q5ZIN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZIN0" } ] }, { "ec_number": "3.1.1.23", "activity": "Hydrolyzes glycerol monoesters of long-chain fatty acids.", "evidence": [ { "id": "Q5ZIN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZIN0" } ] }, { "ec_number": "3.1.-.-", "activity": "", "evidence": [ { "id": "Q5ZIN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZIN0" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1A9U5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9U5" }, { "id": "PF00561", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00561" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "AB hydrolase-1", "eco_id": "ECO_0000259", "start_pos": 73, "end_pos": 182, "start_aa": "Pro", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.1.1.23", "ec_name": "Hydrolyzes glycerol monoesters of long-chain fatty acids.", "evidence": [ { "id": "3.1.1.23", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.1.1.23" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AA18-1", "uniprot_ac": "A0A8V1AA18", "uniprot_id": "A0A8V1AA18_CHICK", "mass": { "chemical_mass": 66962.0, "monoisotopic_mass": 66962.0 }, "refseq": {}, "gene_names": [ { "name": "TRIM29", "type": "recommended", "evidence": [ { "id": "A0A8V1AA18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA18" } ] } ], "protein_names": [ { "name": "Tripartite motif-containing protein 29", "type": "recommended", "evidence": [ { "id": "A0A8V1AA18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA18/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Plays a crucial role in the regulation of macrophage activation in response to viral or bacterial infections within the respiratory tract. Mechanistically, TRIM29 interacts with IKBKG/NEMO in the lysosome where it induces its 'Lys-48' ubiquitination and subsequent degradation. In turn, the expression of type I interferons and the production of pro-inflammatory cytokines are inhibited. Additionally, induces the 'Lys-48' ubiquitination of STING1 in a similar way, leading to its degradation.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7B0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7B0#function" }, { "database": "UniProtKB", "id": "ARBA00056595", "url": "https://www.uniprot.org/uniprotkb/ARBA00056595#function" }, { "database": "UniProtKB", "id": "A0A8V1AA18", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA18#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AA18", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA18" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TRIM29", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA18", "locus": { "chromosome": "24", "start_pos": 3947518, "end_pos": 3924833, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010025978", "url": "https://www.ensembl.org/id/ENSGALG00010025978" } ] } } ], "crossref": [ { "id": "A0A8V1AA18", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AA18", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd19769", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19769", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd19840", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19840", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "419754", "url": "https://www.ncbi.nlm.nih.gov/gene/419754", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000315", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000315", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051051", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051051", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058030", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058030", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A7B0", "url": "https://www.orthodb.org/?gene=A0A8V1A7B0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AA18", "url": "https://www.orthodb.org/?gene=A0A8V1AA18", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR25465", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR25465", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR25465:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR25465:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00643", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00643", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25600", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25600", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1A7B0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7B0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A7B0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7B0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AA18", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA18", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AA18-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA18-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "METGSAARTNGTAGKPEDVKSPSAPKKDEEVKKTTNPGGGEKEPIKGTGGTSLETGQIKSSLFSGSDWKRPIIQFVESSDEKRSTYFSMDSADSKKMPFASGQIGDMRRTPLSFADKGDLRKSLFSLDSKKSFLPNEGEGRKPLFSSGQIGDMKKPSLPLVETGDLRRPTFNKVPDRAAGSRPRVKLEDVLCDSCIDNKQKAVKSCLVCQASFCELHLKPHLEGAAFRDHQLLDPIRDFEARKCPVHGKTMELFCQTDQMCICYLCMFQEHKNHSTVTVEIEKAGKEAELSLQKEQLQLKIIEVEDEVDKWQKERDRIKNYTTNEKATVDQHFKELIRDLERQRDEVKAALDQREKIASENVKEIVDELEERAKLLREDKENREQIHQISDSVLFLQEFGALMRNYVPPPSLPTYSVLLEGESMSPSMGLLRDDLLNVCMRHVEKICKADLGRNFIERNHMENGDHRYMMNNYEWNQPDNLKRFSMFLSPKASFNPRSWEFSSFQATEETLGTGNGTKLPFQFSSVGQNPPGDFSKQSDGSLFTKTAYPSIVRHQSAKVTPQTWKSSKQSVLSHYRPFYVNKGNGATSNEAP", "length": 592, "header": "tr|A0A8V1AA18-1|A0A8V1AA18_CHICK Isoform 1 of Tripartite motif-containing protein 29 OS=Gallus gallus OX=9031 GN=TRIM29 PE=1 SV=1 CANONICAL=A0A8V1AA18-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A7B0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA18/entry#A0A8V1A7B0-1", "sequence": { "sequence": "METGSAARTNGTAGKPEDVKSPSAPKKDEEVKKTTNPGGGEKEPIKGTGGTSLETGQIKSSLFSGSDWKRPIIQFVESSDEKRSTYFSMDSADSKKMPFASGQIGDMRRTPLSFADKGDLRKSLFSLDSKKSFLPNEGEGRKPLFSSGQIGDMKKPSLPLVETGDLRRPTFNKVPDRAAGSRPRVKLEDVLCDSCIDNKQKAVKSCLVCQASFCELHLKPHLEGAAFRDHQLLDPIRDFEARKCPVHGKTMELFCQTDQMCICYLCMFQEHKNHSTVTVEIEKAGKEAELSLQKEQLQLKIIEVEDEVDKWQKERDRIKNYTTNEKATVDQHFKELIRDLERQRDEVKAALDQREKIASENVKEIVDELEERAKLLREDKENREQIHQISDSVLFLQEFGALMRNYVPPPSLPTYSVLLEGESMSPSMGLLRDDLLNVCMRHVEKICKADLGRNFIERNHMENGDHRYMMNNYEWNQPDNLKRFSMFLSPKVGNGTKLPFQFSSVGQNPPGDFSKQSDGSLFTKTAYPSIVRHQSAKVTPQTWKSSKQSVLSHYRPFYVNKGNGATSNEAP", "length": 571, "header": "tr|A0A8V1A7B0-1|A0A8V1AA18_CHICK Computationally mapped isoform of Tripartite motif-containing protein 29 OS=Gallus gallus OX=9031 GN=TRIM29 PE=1 SV=1 CANONICAL=A0A8V1AA18-1" }, "locus": { "chromosome": "24", "start_pos": 3946514, "end_pos": 3924957, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063362.1", "url": "https://www.ensembl.org/id/ENSGALT00010063362.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039110.1", "url": "https://www.ensembl.org/id/ENSGALP00010039110.1" } ] } }, { "isoform_ac": "A0A8V1AA18-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA18/entry#A0A8V1AA18-1", "sequence": { "sequence": "METGSAARTNGTAGKPEDVKSPSAPKKDEEVKKTTNPGGGEKEPIKGTGGTSLETGQIKSSLFSGSDWKRPIIQFVESSDEKRSTYFSMDSADSKKMPFASGQIGDMRRTPLSFADKGDLRKSLFSLDSKKSFLPNEGEGRKPLFSSGQIGDMKKPSLPLVETGDLRRPTFNKVPDRAAGSRPRVKLEDVLCDSCIDNKQKAVKSCLVCQASFCELHLKPHLEGAAFRDHQLLDPIRDFEARKCPVHGKTMELFCQTDQMCICYLCMFQEHKNHSTVTVEIEKAGKEAELSLQKEQLQLKIIEVEDEVDKWQKERDRIKNYTTNEKATVDQHFKELIRDLERQRDEVKAALDQREKIASENVKEIVDELEERAKLLREDKENREQIHQISDSVLFLQEFGALMRNYVPPPSLPTYSVLLEGESMSPSMGLLRDDLLNVCMRHVEKICKADLGRNFIERNHMENGDHRYMMNNYEWNQPDNLKRFSMFLSPKASFNPRSWEFSSFQATEETLGTGNGTKLPFQFSSVGQNPPGDFSKQSDGSLFTKTAYPSIVRHQSAKVTPQTWKSSKQSVLSHYRPFYVNKGNGATSNEAP", "length": 592, "header": "tr|A0A8V1AA18-1|A0A8V1AA18_CHICK Isoform 1 of Tripartite motif-containing protein 29 OS=Gallus gallus OX=9031 GN=TRIM29 PE=1 SV=1 CANONICAL=A0A8V1AA18-1" }, "locus": { "chromosome": "24", "start_pos": 3946514, "end_pos": 3924957, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063360.1", "url": "https://www.ensembl.org/id/ENSGALT00010063360.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039109.1", "url": "https://www.ensembl.org/id/ENSGALP00010039109.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AA18", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA18" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AA18", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA18" } ], "pmid": "" }, { "name": "p53 binding", "id": "GO:0002039", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002039", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AA18", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA18" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AA18", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA18" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "lysosome", "id": "GO:0005764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005764", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AA18", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA18" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AA18", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA18" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 10, "end_pos": 12, "annotation": "n_glycosylation_sequon" }, { "start_pos": 273, "end_pos": 275, "annotation": "n_glycosylation_sequon" }, { "start_pos": 320, "end_pos": 322, "annotation": "n_glycosylation_sequon" }, { "start_pos": 515, "end_pos": 517, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AA18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA18" }, { "id": "PS50119", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50119" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "B box-type", "eco_id": "ECO_0000259", "start_pos": 239, "end_pos": 279, "start_aa": "Phe", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 10, "end_pos": 12 }, { "start_pos": 273, "end_pos": 275 }, { "start_pos": 320, "end_pos": 322 }, { "start_pos": 515, "end_pos": 517 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A7B5-1", "uniprot_ac": "A0A8V1A7B5", "uniprot_id": "A0A8V1A7B5_CHICK", "mass": { "chemical_mass": 17705.0, "monoisotopic_mass": 17705.0 }, "refseq": {}, "gene_names": [ { "name": "CHCHD10", "type": "recommended", "evidence": [ { "id": "A0A8V1A7B5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7B5" } ] } ], "protein_names": [ { "name": "Coiled-coil-helix-coiled-coil-helix domain containing 10", "type": "synonym", "evidence": [ { "id": "A0A8V1A7B5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7B5/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7B5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7B5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CHCHD10", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7B5", "locus": { "chromosome": "15", "start_pos": 7973562, "end_pos": 7974798, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010025985", "url": "https://www.ensembl.org/id/ENSGALG00010025985" } ] } } ], "crossref": [ { "id": "A0A8V1A7B5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A7B5", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR010625", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010625", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055304", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055304", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A7B5", "url": "https://www.orthodb.org/?gene=A0A8V1A7B5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13523", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13523", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13523:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13523:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06747", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06747", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1A7B5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7B5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A7B5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7B5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MARGRRSVSRPAAPPAPASAAPAAPVPAAQPAQPGLMAQMASTAAGVAVGSAVGHVVGSALTGAFGGSSEPPRAAVPAQEPRQQPAVQPQSPYGPCHYEMKQFLECATNQRDLTLCEGFNEALKQCKYSNGERALTPAGGLLRDSGWEGGKAAEQPAVCYVWSSFCPCVSSLL", "length": 173, "header": "tr|A0A8V1A7B5-1|A0A8V1A7B5_CHICK Isoform 1 of Coiled-coil-helix-coiled-coil-helix domain containing 10 OS=Gallus gallus OX=9031 GN=CHCHD10 PE=1 SV=1 CANONICAL=A0A8V1A7B5-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A7B5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7B5/entry#A0A8V1A7B5-1", "sequence": { "sequence": "MARGRRSVSRPAAPPAPASAAPAAPVPAAQPAQPGLMAQMASTAAGVAVGSAVGHVVGSALTGAFGGSSEPPRAAVPAQEPRQQPAVQPQSPYGPCHYEMKQFLECATNQRDLTLCEGFNEALKQCKYSNGERALTPAGGLLRDSGWEGGKAAEQPAVCYVWSSFCPCVSSLL", "length": 173, "header": "tr|A0A8V1A7B5-1|A0A8V1A7B5_CHICK Isoform 1 of Coiled-coil-helix-coiled-coil-helix domain containing 10 OS=Gallus gallus OX=9031 GN=CHCHD10 PE=1 SV=1 CANONICAL=A0A8V1A7B5-1" }, "locus": { "chromosome": "15", "start_pos": 7974784, "end_pos": 7973792, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063375.1", "url": "https://www.ensembl.org/id/ENSGALT00010063375.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039115.1", "url": "https://www.ensembl.org/id/ENSGALP00010039115.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7B5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7B5" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7B5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7B5" } ], "pmid": "" }, { "name": "mitochondrial intermembrane space", "id": "GO:0005758", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005758", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7B5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7B5" } ], "pmid": "" }, { "name": "MICOS complex", "id": "GO:0061617", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061617", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7B5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7B5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "mitochondrion organization", "id": "GO:0007005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007005", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7B5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7B5" } ], "pmid": "" }, { "name": "inner mitochondrial membrane organization", "id": "GO:0007007", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007007", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7B5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7B5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1A7B5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7B5" }, { "id": "PF06747", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06747" } ], "ann_type": 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This record is derived from a genomic sequence (NC_052559.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Mar 1, 2022 this sequence version replaced XP_015155215.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015155215", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015155215" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7D5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7D5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CELF5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7D5", "locus": { "chromosome": "28", "start_pos": 1747784, "end_pos": 1719075, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027133", "url": "https://www.ensembl.org/id/ENSGALG00010027133" } ] } } ], "crossref": [ { "id": "A0A8V1A7D5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A7D5", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd12632", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12632", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12635", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12635", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12639", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12639", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "425867", "url": "https://www.ncbi.nlm.nih.gov/gene/425867", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034648", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034648", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A7D5", "url": "https://www.orthodb.org/?gene=A0A8V1A7D5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24012", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24012", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00076", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00076", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015155215", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015155215", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1A7D5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7D5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A7D5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7D5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSSSGGAEPPAQPDSMKDLDAIKLFVGQIPRNLEEKDLKPLFEQFGKIYELTVLKDRYTGMHKGCAFLTYCARDSAIKAQTALHEQKTLPGMARPIQVKPADSESRGGDRKLFVGMLNKQQSEDDVLRLFEPFGVIDECTVLRGPDGNSKGCAFVKFSSHTEAQAAIHALHGSQTMPGASSSLVVKFADTDKERTLRRMQQMVGQLGIFTPSLTLPFSPYSAYAQALMQQQTTVLSTSHGSYLSPGVAFSPCHIQQIGAVSLNGLPAAPIAQTSGLHSPPLLGTTAMPGLVAPISNGFTGVVPFPNGHPALETVYTNGFVPYSAQSPSVAETLHPAFSGVQQYAAVYPTTSITPIAQSIPQPPPVLQQQQREGPEGCNLFIYHLPQEFGDNELMQMFLPFGNIISSKVFMDRATNQSKCFGFVSFDNPSSAQTAIQAMNGFQIGMKRLKVQLKRPKDANHPY", "length": 462, "header": "tr|A0A8V1A7D5-1|A0A8V1A7D5_CHICK Isoform 1 of CUGBP Elav-like family member 5 OS=Gallus gallus OX=9031 GN=CELF5 PE=3 SV=1 CANONICAL=A0A8V1A7D5-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A7D5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7D5/entry#A0A8V1A7D5-1", "sequence": { "sequence": "MSSSGGAEPPAQPDSMKDLDAIKLFVGQIPRNLEEKDLKPLFEQFGKIYELTVLKDRYTGMHKGCAFLTYCARDSAIKAQTALHEQKTLPGMARPIQVKPADSESRGGDRKLFVGMLNKQQSEDDVLRLFEPFGVIDECTVLRGPDGNSKGCAFVKFSSHTEAQAAIHALHGSQTMPGASSSLVVKFADTDKERTLRRMQQMVGQLGIFTPSLTLPFSPYSAYAQALMQQQTTVLSTSHGSYLSPGVAFSPCHIQQIGAVSLNGLPAAPIAQTSGLHSPPLLGTTAMPGLVAPISNGFTGVVPFPNGHPALETVYTNGFVPYSAQSPSVAETLHPAFSGVQQYAAVYPTTSITPIAQSIPQPPPVLQQQQREGPEGCNLFIYHLPQEFGDNELMQMFLPFGNIISSKVFMDRATNQSKCFGFVSFDNPSSAQTAIQAMNGFQIGMKRLKVQLKRPKDANHPY", "length": 462, "header": "tr|A0A8V1A7D5-1|A0A8V1A7D5_CHICK Isoform 1 of CUGBP Elav-like family member 5 OS=Gallus gallus OX=9031 GN=CELF5 PE=3 SV=1 CANONICAL=A0A8V1A7D5-1" }, "locus": { "chromosome": "28", "start_pos": 1747744, "end_pos": 1719123, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065775.1", "url": "https://www.ensembl.org/id/ENSGALT00010065775.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040041.1", "url": "https://www.ensembl.org/id/ENSGALP00010040041.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 349, "start_aa": "Thr", "end_pos": 349, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr349", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7D5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7D5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7D5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7D5" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7D5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7D5" } ], "pmid": "" }, { "name": "ribonucleoprotein complex", "id": "GO:1990904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990904", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7D5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7D5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "mRNA splice site recognition", "id": "GO:0006376", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006376", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7D5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7D5" } ], "pmid": "" }, { "name": "regulation of alternative mRNA splicing, via spliceosome", "id": "GO:0000381", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000381", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7D5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7D5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 415, "end_pos": 417, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1A7D5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7D5" }, { "id": "PS50102", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50102" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RRM", "eco_id": "ECO_0000259", "start_pos": 22, "end_pos": 103, "start_aa": "Ile", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 349 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 415, "end_pos": 417 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A7E7-1", "uniprot_ac": "A0A8V1A7E7", "uniprot_id": "A0A8V1A7E7_CHICK", "mass": { "chemical_mass": 86580.0, "monoisotopic_mass": 86580.0 }, "refseq": {}, "gene_names": [ { "name": "CACTIN", "type": "recommended", "evidence": [ { "id": "A0A8V1A7E7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E7" } ] } ], "protein_names": [ { "name": "Splicing factor Cactin", "type": "recommended", "evidence": [ { "id": "A0A8V1A7E7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E7/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7E7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CACTIN", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E7", "locus": { "chromosome": "28", "start_pos": 1456264, "end_pos": 1450700, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028115", "url": "https://www.ensembl.org/id/ENSGALG00010028115" } ] } } ], "crossref": [ { "id": "A0A8V1A7E7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A7E7", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR018816", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018816", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019134", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019134", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A7E7", "url": "https://www.orthodb.org/?gene=A0A8V1A7E7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AHI7", "url": "https://www.orthodb.org/?gene=A0A8V1AHI7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21737", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21737", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21737:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21737:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF09732", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09732", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF10312", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10312", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1A7E7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A7E7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHI7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHI7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHI7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHI7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGSGSRSRDRRDRERDRERSGSEGKRRRSRSRSRGRRREASSGSDSNDERQKWKKKSKNRDQHHKSQRKHRSRSRGRSSDSSAERDRRRARSRDRRRRRAGSKSSVSSVSSPSPPRSRGQEESGQQLSLQERLRMKEEKKKQAALMKALETPEEKRARRLAKKEAKERKKREKMGWGEEYMGYTNTDNPFGDNNLLGTFIWSKALEKKGISHLDEKDLKERNKRIQEDNRLELQKQVKQLRLEREREKAMREQELEMLQREKEAEHFKTWEEQEDNFHLQQAKLRSKIRIRDGRAKPIDLLAKYISAEDDDLAVEMHEPYTFLNGLTVSDMEDLVEDIQVYMELEQGKNVDFWRDMTIITEDEIAKLRKLEASGKGGPGERRDGVNASVSSDVQSVFKGKTYNQLQVLYQGIESKIRAGGPNLDIGYWESLLQQLKAYMARARLRERHQDVLRQKLYKLKQEQGVESEPLFPIIKREPVSPSDRLDAEESIVVQPGPSSEPEAEQDVEVKEEAEGEAVLMEEDLIQQSLDDYDAGKYSPRLLGTNELPFDAHVLEAEEDTHRLLLLRQQLQVTGNATESADDIFFRKAKEGMGADEAQFSVEMPLTGKAYLWADKYRPRKPRFFNRVHTGFEWNKYNQTHYDFDNPPPKIVQGYKFNIFYPDLIDKRSTPEYFLEACQDNKDFAILRFHAGPPYEDIAFKIVNREWEYSHRHGFRCQFANGIFQLWFHFKRYRYRR", "length": 736, "header": "tr|A0A8V1A7E7-1|A0A8V1A7E7_CHICK Isoform 1 of Splicing factor Cactin OS=Gallus gallus OX=9031 GN=CACTIN PE=1 SV=1 CANONICAL=A0A8V1A7E7-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A7E7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E7/entry#A0A8V1A7E7-1", "sequence": { "sequence": "MGSGSRSRDRRDRERDRERSGSEGKRRRSRSRSRGRRREASSGSDSNDERQKWKKKSKNRDQHHKSQRKHRSRSRGRSSDSSAERDRRRARSRDRRRRRAGSKSSVSSVSSPSPPRSRGQEESGQQLSLQERLRMKEEKKKQAALMKALETPEEKRARRLAKKEAKERKKREKMGWGEEYMGYTNTDNPFGDNNLLGTFIWSKALEKKGISHLDEKDLKERNKRIQEDNRLELQKQVKQLRLEREREKAMREQELEMLQREKEAEHFKTWEEQEDNFHLQQAKLRSKIRIRDGRAKPIDLLAKYISAEDDDLAVEMHEPYTFLNGLTVSDMEDLVEDIQVYMELEQGKNVDFWRDMTIITEDEIAKLRKLEASGKGGPGERRDGVNASVSSDVQSVFKGKTYNQLQVLYQGIESKIRAGGPNLDIGYWESLLQQLKAYMARARLRERHQDVLRQKLYKLKQEQGVESEPLFPIIKREPVSPSDRLDAEESIVVQPGPSSEPEAEQDVEVKEEAEGEAVLMEEDLIQQSLDDYDAGKYSPRLLGTNELPFDAHVLEAEEDTHRLLLLRQQLQVTGNATESADDIFFRKAKEGMGADEAQFSVEMPLTGKAYLWADKYRPRKPRFFNRVHTGFEWNKYNQTHYDFDNPPPKIVQGYKFNIFYPDLIDKRSTPEYFLEACQDNKDFAILRFHAGPPYEDIAFKIVNREWEYSHRHGFRCQFANGIFQLWFHFKRYRYRR", "length": 736, "header": "tr|A0A8V1A7E7-1|A0A8V1A7E7_CHICK Isoform 1 of Splicing factor Cactin OS=Gallus gallus OX=9031 GN=CACTIN PE=1 SV=1 CANONICAL=A0A8V1A7E7-1" }, "locus": { "chromosome": "28", "start_pos": 1456036, "end_pos": 1450761, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068126.1", "url": "https://www.ensembl.org/id/ENSGALT00010068126.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041869.1", "url": "https://www.ensembl.org/id/ENSGALP00010041869.1" } ] } }, { "isoform_ac": "A0A8V1AHI7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E7/entry#A0A8V1AHI7-1", "sequence": { "sequence": "MKVPRETQHLRGGWDAVTHHHRAPKEGLALLLTMGTQYSSDSNDERQKWKKKSKNRDQHHKSQRKHRSRSRGRSSDSSAERDRRRARSRDRRRRRAGSKSSVSSVSSPSPPRSRGQEESGQQLSLQERLRMKEEKKKQAALMKALETPEEKRARRLAKKEAKERKKREKMGWGEEYMGYTNTDNPFGDNNLLGTFIWSKALEKKGISHLDEKDLKERNKRIQEDNRLELQKVKQLRLEREREKAMREQELEMLQREKEAEHFKTWEEQEDNFHLQQAKLRSKIRIRDGRAKPIDLLAKYISAEDDDLAVEMHEPYTFLNGLTVSDMEDLVEDIQVYMELEQGKNVDFWRDMTIITEDEIAKLRKLEASGKGGPGERRDGVNASVSSDVQSVFKGKTYNQLQVLYQGIESKIRAGGPNLDIGYWESLLQQLKAYMARARLRERHQDVLRQKLYKLKQEQGVESEPLFPIIKREPVSPSDRLDAEESIVVQPGPSSEPEAEQDVEVKEEAEGEAVLMEEDLIQQSLDDYDAGKYSPRLLGTNELPFDAHVLEAEEDTHRLLLLRQQLQVTGNATESADDIFFRKAKEGMGADEAQFSVEMPLTGKAYLWADKYRPRKPRFFNRVHTGFEWNKYNQTHYDFDNPPPKIVQGYKFNIFYPDLIDKRSTPEYFLEACQDNKDFAILRFHAGPPYEDIAFKIVNREWEYSHRHGFRCQFANGIFQLWFHFKRYRYRR", "length": 731, "header": "tr|A0A8V1AHI7-1|A0A8V1A7E7_CHICK Computationally mapped isoform of Splicing factor Cactin OS=Gallus gallus OX=9031 GN=CACTIN PE=1 SV=1 CANONICAL=A0A8V1A7E7-1" }, "locus": { "chromosome": "28", "start_pos": 1456036, "end_pos": 1451644, 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"https://www.ncbi.nlm.nih.gov/protein/XP_015132617" } ] } ], "protein_names": [ { "name": "F-box/SPRY domain-containing protein 1", "type": "recommended", "evidence": [ { "id": "A0A8V1A7G4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7G4/entry#names_and_taxonomy" } ] }, { "name": "F-box only protein 45", "type": "synonym", "evidence": [ { "id": "A0A8V1A7G4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7G4/entry#names_and_taxonomy" } ] }, { "name": "F-box/SPRY domain-containing protein 1", "type": "synonym", "evidence": [ { "id": "XP_015132617", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015132617" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052540.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015132617", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015132617" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7G4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7G4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FBXO45", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7G4", "locus": { "chromosome": "9", "start_pos": 4355061, "end_pos": 4359866, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010024798", "url": "https://www.ensembl.org/id/ENSGALG00010024798" } ] } } ], "crossref": [ { "id": "A0A8V1A7G4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A7G4", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd12907", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12907", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd22111", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22111", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "770111", "url": "https://www.ncbi.nlm.nih.gov/gene/770111", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001810", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001810", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001870", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001870", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003877", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003877", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035784", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035784", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036047", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036047", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043136", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043136", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050672", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050672", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:770111", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:770111", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ATKRASM", "url": "https://omabrowser.org/oma/group/ATKRASM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A7G4", "url": "https://www.orthodb.org/?gene=A0A8V1A7G4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12245", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12245", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12245:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12245:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00622", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00622", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12937", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12937", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015132617", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015132617", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1A7G4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7G4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A7G4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7G4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAGPGGGAAGGAGWRLPGRVLELVFSYLELRELRSCALVCKLWHHVLHGDENSEVWRSLAARCLAEEALRTDILCNVPTYKGKVRAFHHAFSTNDCSRNVYIKKNGFTLHRNPIAQSTDGARTKIGFSEGRHAWEVWWEGPLGTVAVIGIATKRAAMQCQGYVALLGSDDQSWGWNLVDNNLLHNGEVNGSFPQCNNAPKYQIGERIRVILDMEDKTLAFERGYEFLGVAFRGLPKVCLYPAVSAVYGNTEVTLVYLGKPLDG", "length": 264, "header": "tr|A0A8V1A7G4-1|A0A8V1A7G4_CHICK Isoform 1 of F-box/SPRY domain-containing protein 1 OS=Gallus gallus OX=9031 GN=FBXO45 PE=3 SV=1 CANONICAL=A0A8V1A7G4-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A7G4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7G4/entry#A0A8V1A7G4-1", "sequence": { "sequence": "MAAGPGGGAAGGAGWRLPGRVLELVFSYLELRELRSCALVCKLWHHVLHGDENSEVWRSLAARCLAEEALRTDILCNVPTYKGKVRAFHHAFSTNDCSRNVYIKKNGFTLHRNPIAQSTDGARTKIGFSEGRHAWEVWWEGPLGTVAVIGIATKRAAMQCQGYVALLGSDDQSWGWNLVDNNLLHNGEVNGSFPQCNNAPKYQIGERIRVILDMEDKTLAFERGYEFLGVAFRGLPKVCLYPAVSAVYGNTEVTLVYLGKPLDG", "length": 264, "header": "tr|A0A8V1A7G4-1|A0A8V1A7G4_CHICK Isoform 1 of F-box/SPRY domain-containing protein 1 OS=Gallus gallus OX=9031 GN=FBXO45 PE=3 SV=1 CANONICAL=A0A8V1A7G4-1" }, "locus": { "chromosome": "9", "start_pos": 4359809, "end_pos": 4356974, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010060536.1", "url": "https://www.ensembl.org/id/ENSGALT00010060536.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010037295.1", "url": "https://www.ensembl.org/id/ENSGALP00010037295.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:770111", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:770111", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "G5E639-1", "protein_name": "F-box/SPRY domain-containing protein 1", "gene_name": "FBXO45", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAAPAPGAGAASGGAGCSGGGAGAGSGSGAGGRLPSRVLELVFSYLELSELRSCALVCKHWYRCLHGDENSEVWRSLCARSLAEEALRTDILCNLPSYKAKIRAFQHAFSTNDCSRNVYIKKNGFTLHRNPIAQSTDGARTKIGFSEGRHAWEVWWEGPLGTVAVIGIATKRAPMQCQGYVALLGSDDQSWGWNLVDNNLLHNGEVNGSFPQCNNAPKYQIGERIRVILDMEDKTLAFERGYEFLGVAFRGLPKVCLYPAVSAVYGNTEVTLVYLGKPLDG", "length": 281 }, "evidence": [ { "id": "A0A8V1A7G4", "url": "https://omabrowser.org/oma/group/A0A8V1A7G4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P0C2W1-1", "protein_name": "F-box/SPRY domain-containing protein 1", "gene_name": "FBXO45", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAPAPGAGAASGGAGCSGGGAGAGAGSGSGAAGAGGRLPSRVLELVFSYLELSELRSCALVCKHWYRCLHGDENSEVWRSLCARSLAEEALRTDILCNLPSYKAKIRAFQHAFSTNDCSRNVYIKKNGFTLHRNPIAQSTDGARTKIGFSEGRHAWEVWWEGPLGTVAVIGIATKRAPMQCQGYVALLGSDDQSWGWNLVDNNLLHNGEVNGSFPQCNNAPKYQIGERIRVILDMEDKTLAFERGYEFLGVAFRGLPKVCLYPAVSAVYGNTEVTLVYLGKPLDG", "length": 286 }, "evidence": [ { "id": "A0A8V1A7G4", "url": "https://omabrowser.org/oma/group/A0A8V1A7G4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0CH38-1", "protein_name": "F-box/SPRY domain-containing protein 1", "gene_name": "Fbxo45", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "LASRALVCKHWYRCLHGDENSEVWRSLCARSLEEAMRTDILCNLPSYKAKVRAFQHAFSTNDCSRNVYIKKNGFTLHRNPIAQSTDGARTKIGFSEGRHAWEVWWEGPLGTVAVIGIATKRAPMQCQGYVALLGSDDQSWGWNLVDNNLLHNGEVNGSFPQCNNAPKYQIGERIRVILDMEDKTLAFERGYEFLGVAFRGLPKACLYPAVSAVYGNTEVTLVYLGKPLDG", "length": 230 }, "evidence": [ { "id": "A0A8V1A7G4", "url": "https://omabrowser.org/oma/group/A0A8V1A7G4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6NZ03-1", "protein_name": "F-box/SPRY domain-containing protein 1", "gene_name": "fbxo45", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSGAVATGGAQSAGLGAAAAGCCSSASGAGSAALLSGGSGIAGRLPSRVLEHIFSYLELMDLLNCSLVCWHWNNCLSDENSEVWRSLCARSLSDEAMRSDILCNLASYKGKLKSFQHALSSHDCSRNVYIKKNGFTLHRNPIAQSTDGARGKIGFSEGRHAWEIWWEGPLGTVAVIGIATKRAPMQCQGYVALLGSDDQSWGWNLVDNNLLHNGEVNGNFPQCNNAPKYQIGERIRVILDMDDKTLAFERGFEFLGVAFRGLPKTCLFPAVSAVYGNTEVTMVYLGRPLDG", "length": 291 }, "evidence": [ { "id": "A0A8V1A7G4", "url": "https://omabrowser.org/oma/group/A0A8V1A7G4/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8K3B1-1", "protein_name": "F-box/SPRY domain-containing protein 1", "gene_name": "Fbxo45", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAPGPGAGAASGGASGGGAGAGGGASAGSGSSGVGGRLPSRVLELVFSYLELSELRSCALVCKHWYRCLHGDENSEVWRSLCARSLAEEALRTDILCNLPSYKAKVRAFQHAFSTNDCSRNVYIKKNGFTLHRNPIAQSTDGARTKIGFSEGRHAWEVWWEGPLGTVAVIGIATKRAPMQCQGYVALLGSDDQSWGWNLVDNNLLHNGEVNGSFPQCNNAPKYQIGERIRVILDMEDKTLAFERGYEFLGVAFRGLPKACLYPAVSAVYGNTEVTLVYLGKPLDG", "length": 286 }, "evidence": [ { "id": "A0A8V1A7G4", "url": "https://omabrowser.org/oma/group/A0A8V1A7G4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9V6L9-1", "protein_name": "F-box/SPRY domain-containing protein 1", "gene_name": "Fsn", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MVDPVAALCNYNVLEVIFSYLELDDLSHCSQVCKSWYHFLNDENSDVWRWHCLNKLPKESLKSDLLASVSTYKTKLRAYFHAWSPNDCSRNVYIKPNGFTLHRNPVAQSTDAARGKIGFRHGRHTWEVIWEGPLGTVAVIGISTKEAALQCHGYVALLGSDDQSWGWNLVENHLLHNGDMQGSYPLLNNAPKYQVGERIRVILDCEDNTLSFEKNYEFLGVAFRGLPDKKLYPTVSAVYGNTEVSMVYLGTPLDG", "length": 255 }, "evidence": [ { "id": "A0A8V1A7G4", "url": "https://omabrowser.org/oma/group/A0A8V1A7G4/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7G4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7G4" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7G4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7G4" } ], "pmid": "" }, { "name": "postsynaptic density", "id": "GO:0014069", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014069", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7G4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7G4" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": 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"A0A8V1AA60-1", "uniprot_ac": "A0A8V1AA60", "uniprot_id": "A0A8V1AA60_CHICK", "mass": { "chemical_mass": 88983.0, "monoisotopic_mass": 88983.0 }, "refseq": {}, "gene_names": [ { "name": "TPCN2", "type": "recommended", "evidence": [ { "id": "A0A8V1AA60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA60" } ] } ], "protein_names": [ { "name": "Two pore channel protein 2", "type": "recommended", "evidence": [ { "id": "A0A8V1AA60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA60/entry#names_and_taxonomy" } ] }, { "name": "Two pore calcium channel protein 2", "type": "synonym", "evidence": [ { "id": "A0A8V1AA60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA60/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AA60", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA60" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TPCN2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA60", "locus": { "chromosome": "5", "start_pos": 16694818, "end_pos": 16672872, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010025386", "url": "https://www.ensembl.org/id/ENSGALG00010025386" } ] } } ], "crossref": [ { "id": "A0A8V1AA60", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AA60", "database": "AlphaFoldDB", "categories": [] }, { "id": "423141", "url": "https://www.ncbi.nlm.nih.gov/gene/423141", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR005821", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005821", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027359", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027359", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028798", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028798", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:423141", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423141", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FTESIEM", "url": "https://omabrowser.org/oma/group/FTESIEM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A7H0", "url": "https://www.orthodb.org/?gene=A0A8V1A7H0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AA60", "url": "https://www.orthodb.org/?gene=A0A8V1AA60", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46768", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46768", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46768:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46768:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00520", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00520", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-2672351", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2672351", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "29671", "url": "https://www.rhea-db.org/rhea/29671", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "34963", "url": "https://www.rhea-db.org/rhea/34963", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1A7H0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7H0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A7H0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7H0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AA60", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA60", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AA60-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA60-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEAGAAAETEPLLPPRSWRAARGAAGAAEDLHINQAVVFIEDAIQYRSINHRVDSKSLWLYRWYYSRICQWILSLTITIILALAFVETPSSLTVTSDVRYRLPAWDPLCGLTESIELLCFLVFMIDVSVKSYLIGWEEFWKNKWLMAYIVTLIISLTDWVVSLSFFCTETVRVRRILRPFFLLQNSSMMKKTLKSINSTLPEMASVVLLLAVHLSLFTMFAMLLFARTKDGQQDKEWVGYFRNLPDSLTSLLVLLTTANNPDVMIPAYSKNRAYSIFFILFTVLGNLFLMNLLTAIIYNQFRGYLLKSVQSSLFRRRLGIRAAFEVLSSLKETPANSEQSCVSAGAVLQVLQKVEMDSRCKQAIMMSLKICSCDQLSAAQFQRLFEELDKDAIKQHPPSPEYRSHFMRKMQFAFGHPYFGYLGNVVALANIVSICVVLVLDADKQPSERDDFFLGTINCFFIIYYLMEMLLKILAMGLKRYLSYPSNRFDGLLTTILLVLEIATFAEYGFPHPGWRPEFVGLLSLWDMVRLANMLIVFRFLRIIPNMKFMSLVVTTLLDLVKNLRAFAGILVVVFYAFAITGIMLFKGAVVPMGNVSVVNTTYNNGTLQCGTYEQLEYWPNNFDDFAAALVTLWDVMVVNNWQVFLEAFSRYTSPWAKIYFVAWWLISSVIWVNLFVALLLENFIHKWDRRCHRESLSDIEYQRTVELMFRDVLEEPTEEELMEKLQQHPHLHLYFSLSITFYYNLPKQHELVWNYHHQCLSNAVLPSTQG", "length": 771, "header": "tr|A0A8V1AA60-1|A0A8V1AA60_CHICK Isoform 1 of Two pore channel protein 2 OS=Gallus gallus OX=9031 GN=TPCN2 PE=1 SV=1 CANONICAL=A0A8V1AA60-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A7H0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA60/entry#A0A8V1A7H0-1", "sequence": { "sequence": "MEAGAAAETEPLLPPRSWRAARGAAGAAEDLHINQAVVFIEDAIQYRSINHRVDSKSLWLYRWYYSRICQWILSLTITIILALAFVETPSSLTVTSDVRYRLPAWDPLCGLTESIELLCFLVFMIDVSVKSYLIGWEEFWKNKWLMAYIVTLIISLTDWVVSLSFFCTETVRVRRILRPFFLLQNSSMMKKTLKSINSTLPEMASVVLLLAVHLSLFTMFAMLLFARTKDGQQDKEWVGYFRNLPDSLTSLLVLLTTANNPDVMIPAYSKNRAYSIFFILFTVLGNLFLMNLLTAIIYNQFRGYLLKSVQSSLFRRRLGIRAAFEVLSSLKETPANSEQSCVSAGAVLQVLQKVEMDSRCKQAIMMSLKICSCDQLSAAQFQRLFEELDKDAIKQHPPSPEYRSHFMRKMQFAFGHPYFGYLGNVVALANIVSICVVLVLDADKQPSERDDFFLGTINCFFIIYYLMEMLLKILAMGLKRYLSYPSNRFDGLLTTILLVLEIATFAEYGFPHPGWRPEFVGLLSLWDMVRLANMLIVFRFLRIIPNMKFMSLVVTTLLDLVKNLRAFAGILVVVFYAFAITGIMLFKGAVVPMGNVSVVNTTYNNGTLQCGTYEQLEYWPNNFDDFAAALVTLWDVMVVNNWQVFLEAFSRYTSPWAKIYFVAWWLISSVIWVNLFVALLLENFIHKWDRRCHRESLSDIEYQRTVELMFRDVLEEPTEEELMEKLQQHPHLHLCR", "length": 736, "header": "tr|A0A8V1A7H0-1|A0A8V1AA60_CHICK Computationally mapped isoform of Two pore channel protein 2 OS=Gallus gallus OX=9031 GN=TPCN2 PE=1 SV=1 CANONICAL=A0A8V1AA60-1" }, "locus": { "chromosome": "5", "start_pos": 16692428, "end_pos": 16672923, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010061994.1", "url": "https://www.ensembl.org/id/ENSGALT00010061994.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038287.1", "url": "https://www.ensembl.org/id/ENSGALP00010038287.1" } ] } }, { "isoform_ac": "A0A8V1AA60-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA60/entry#A0A8V1AA60-1", "sequence": { "sequence": "MEAGAAAETEPLLPPRSWRAARGAAGAAEDLHINQAVVFIEDAIQYRSINHRVDSKSLWLYRWYYSRICQWILSLTITIILALAFVETPSSLTVTSDVRYRLPAWDPLCGLTESIELLCFLVFMIDVSVKSYLIGWEEFWKNKWLMAYIVTLIISLTDWVVSLSFFCTETVRVRRILRPFFLLQNSSMMKKTLKSINSTLPEMASVVLLLAVHLSLFTMFAMLLFARTKDGQQDKEWVGYFRNLPDSLTSLLVLLTTANNPDVMIPAYSKNRAYSIFFILFTVLGNLFLMNLLTAIIYNQFRGYLLKSVQSSLFRRRLGIRAAFEVLSSLKETPANSEQSCVSAGAVLQVLQKVEMDSRCKQAIMMSLKICSCDQLSAAQFQRLFEELDKDAIKQHPPSPEYRSHFMRKMQFAFGHPYFGYLGNVVALANIVSICVVLVLDADKQPSERDDFFLGTINCFFIIYYLMEMLLKILAMGLKRYLSYPSNRFDGLLTTILLVLEIATFAEYGFPHPGWRPEFVGLLSLWDMVRLANMLIVFRFLRIIPNMKFMSLVVTTLLDLVKNLRAFAGILVVVFYAFAITGIMLFKGAVVPMGNVSVVNTTYNNGTLQCGTYEQLEYWPNNFDDFAAALVTLWDVMVVNNWQVFLEAFSRYTSPWAKIYFVAWWLISSVIWVNLFVALLLENFIHKWDRRCHRESLSDIEYQRTVELMFRDVLEEPTEEELMEKLQQHPHLHLYFSLSITFYYNLPKQHELVWNYHHQCLSNAVLPSTQG", "length": 771, "header": "tr|A0A8V1AA60-1|A0A8V1AA60_CHICK Isoform 1 of Two pore channel protein 2 OS=Gallus gallus OX=9031 GN=TPCN2 PE=1 SV=1 CANONICAL=A0A8V1AA60-1" }, "locus": { "chromosome": "5", "start_pos": 16694586, "end_pos": 16672923, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010061997.1", "url": "https://www.ensembl.org/id/ENSGALT00010061997.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038290.1", "url": "https://www.ensembl.org/id/ENSGALP00010038290.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:423141", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423141", "resource": "KEGG Pathway" }, { "id": "R-GGA-2672351", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2672351", "resource": "Reactome", "description": "Stimuli-sensing channels" } ], "orthologs": [ { "uniprot_canonical_ac": "Q8BWC0-1", "protein_name": "Two pore channel protein 2", "gene_name": "Tpcn2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAEEQPLLGRDRGSGQVHSGAAADQELCIDQAVVFIEDAIKYRSIYHRMDAGSLWLYRWYYSNVCQRVLGFIIFLILILAFVEVPSSFTKTADVRYRSQPWQPPCGLTETIEAFCLLAFLVDLSVKGYLVGQAQLQQNLWLLAYFMVLVVSVVDWIVSLSLACEEPLRMRRLLRPFFLLQNSSMMKKTLKCIRWSLPEMASVGLLLAIHLCLFTIIGMLLFTIGEKDEAQDQERLAYFRNLPEALTSLLVLLTTSNNPDVMIPAYTQNRAFALFFIVFTLIGSLFLMNLLTAIIYNQFRGYLMKSLQTSLFRRRLGARAAYEVLASRAGPAGTTPELVGVNPETFLPVLQKTQLNKTHKQAIMQKVQSYEGRPMLADEFQKLFDEVDKGLAKERPLKPQYQSPFLQTAQFIFSHHYFDYLGNLVALGNLLSICVFLVLDSDLLPGERDDFVLGILDYIFILYYLLELLFKVFALGLPGYLSYHSNVFDGLLTIILLVSEICTLAVYRLPHSGWKPEQYGPLSLWDMTRLMNTLIVFRFLRIIPNIKPMAEVANTILGLIPNLRAFGGILVVAYYVFAMIGINLFRGVIVPPGNSSLVPDNNSAVCGSFEQLGYWPNNFDDFAAALITLWNVMVVNNWQVILEAYKRYAGPWSMVYFVLWWLVSSVIWINLFLALLLENFLHRWDPQGHKQLLVGTKQMSVELMFRDILEEPKEEELMEKLHKHPHLHLCR", "length": 731 }, "evidence": [ { "id": "A0A8V1AA60", "url": "https://omabrowser.org/oma/group/A0A8V1AA60/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8NHX9-1", "protein_name": "Two pore channel protein 2", "gene_name": "TPCN2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAEPQAESEPLLGGARGGGGDWPAGLTTYRSIQVGPGAAARWDLCIDQAVVFIEDAIQYRSINHRVDASSMWLYRRYYSNVCQRTLSFTIFLILFLAFIETPSSLTSTADVRYRAAPWEPPCGLTESVEVLCLLVFAADLSVKGYLFGWAHFQKNLWLLGYLVVLVVSLVDWTVSLSLVCHEPLRIRRLLRPFFLLQNSSMMKKTLKCIRWSLPEMASVGLLLAIHLCLFTMFGMLLFAGGKQDDGQDRERLTYFQNLPESLTSLLVLLTTANNPDVMIPAYSKNRAYAIFFIVFTVIGSLFLMNLLTAIIYSQFRGYLMKSLQTSLFRRRLGTRAAFEVLSSMVGEGGAFPQAVGVKPQNLLQVLQKVQLDSSHKQAMMEKVRSYGSVLLSAEEFQKLFNELDRSVVKEHPPRPEYQSPFLQSAQFLFGHYYFDYLGNLIALANLVSICVFLVLDADVLPAERDDFILGILNCVFIVYYLLEMLLKVFALGLRGYLSYPSNVFDGLLTVVLLVLEISTLAVYRLPHPGWRPEMVGLLSLWDMTRMLNMLIVFRFLRIIPSMKLMAVVASTVLGLVQNMRAFGGILVVVYYVFAIIGINLFRGVIVALPGNSSLAPANGSAPCGSFEQLEYWANNFDDFAAALVTLWNLMVVNNWQVFLDAYRRYSGPWSKIYFVLWWLVSSVIWVNLFLALILENFLHKWDPRSHLQPLAGTPEATYQMTVELLFRDILEEPGEDELTERLSQHPHLWLCR", "length": 752 }, "evidence": [ { "id": "A0A8V1AA60", "url": "https://omabrowser.org/oma/group/A0A8V1AA60/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 9, "go_terms": [ { "name": "calcium channel activity", "id": "GO:0005262", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005262", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AA60", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA60" } ], "pmid": "" }, { "name": "voltage-gated channel activity", "id": "GO:0022832", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022832", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AA60", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA60" } ], "pmid": "" }, { "name": "NAADP-sensitive calcium-release channel activity", "id": "GO:0072345", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072345", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AA60", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA60" } ], "pmid": "" }, { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AA60", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA60" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AA60", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA60" } ], "pmid": "" }, { "name": "phosphatidylinositol-3,5-bisphosphate binding", "id": "GO:0080025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0080025", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AA60", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA60" } ], "pmid": "" }, { "name": "ligand-gated sodium channel activity", "id": "GO:0015280", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015280", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AA60", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA60" } ], "pmid": "" }, { "name": "voltage-gated calcium channel activity", "id": "GO:0005245", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005245", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AA60", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA60" } ], "pmid": "" }, { "name": "intracellularly phosphatidylinositol-3,5-bisphosphate-gated monatomic cation channel activity", "id": "GO:0097682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097682", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AA60", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA60" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 12, "go_terms": [ { "name": "calcium-mediated signaling", "id": "GO:0019722", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019722", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AA60", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA60" } ], "pmid": "" }, { "name": "smooth muscle contraction", "id": "GO:0006939", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006939", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AA60", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA60" } ], "pmid": "" }, { "name": "regulation of autophagy", "id": "GO:0010506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010506", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AA60", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA60" } ], "pmid": "" }, { "name": "intracellular calcium ion homeostasis", "id": "GO:0006874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006874", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AA60", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA60" } ], "pmid": "" }, { "name": "lysosome organization", "id": "GO:0007040", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007040", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AA60", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA60" } ], "pmid": "" }, { "name": "release of sequestered calcium ion into cytosol", "id": "GO:0051209", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051209", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AA60", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA60" } ], "pmid": "" }, { "name": "receptor-mediated endocytosis of virus by host cell", "id": "GO:0019065", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019065", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AA60", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA60" } ], "pmid": "" }, { "name": "regulation of exocytosis", "id": "GO:0017157", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017157", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AA60", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA60" } ], "pmid": "" }, { "name": "intracellular pH reduction", "id": "GO:0051452", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051452", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AA60", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA60" } ], "pmid": "" }, { "name": "endocytosis involved in viral entry into host cell", "id": "GO:0075509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0075509", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AA60", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA60" } ], "pmid": "" }, { "name": "negative regulation of developmental pigmentation", "id": "GO:0048086", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048086", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AA60", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA60" } ], "pmid": "" }, { "name": "endosome to lysosome transport of low-density lipoprotein particle", "id": "GO:0090117", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090117", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AA60", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA60" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "lysosomal membrane", "id": "GO:0005765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005765", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AA60", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA60" } ], "pmid": "" }, { "name": "late endosome membrane", "id": "GO:0031902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031902", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AA60", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA60" } ], "pmid": "" }, { "name": "monoatomic ion channel complex", "id": "GO:0034702", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034702", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AA60", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA60" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AA60", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA60" } ], "pmid": "" }, { "name": "endolysosome membrane", "id": "GO:0036020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AA60", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA60" } ], "pmid": "" }, { "name": "melanosome membrane", "id": "GO:0033162", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033162", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AA60", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA60" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 185, "end_pos": 187, "annotation": "n_glycosylation_sequon" }, { "start_pos": 197, "end_pos": 199, "annotation": "n_glycosylation_sequon" }, { "start_pos": 595, "end_pos": 597, "annotation": "n_glycosylation_sequon" }, { "start_pos": 600, "end_pos": 602, "annotation": "n_glycosylation_sequon" }, { "start_pos": 605, "end_pos": 607, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "29671", "name": "", "equation": "Ca(2+)(in) = Ca(2+)(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YTN5-1", "A0A8V0YTP2-1" ], "evidence": [ { "id": "29671", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/29671" } ] }, { "id": "34963", "name": "", "equation": "Na(+)(in) = Na(+)(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "34963", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/34963" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0YTN5", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTN5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTN5" } ] } ] }, { "uniprot_ac": "A0A8V0YTP2", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTP2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTP2" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AA60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA60" }, { "id": "PF00520", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00520" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ion transport", "eco_id": "ECO_0000259", "start_pos": 72, "end_pos": 301, "start_aa": "Ile", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 185, "end_pos": 187 }, { "start_pos": 197, "end_pos": 199 }, { "start_pos": 595, "end_pos": 597 }, { "start_pos": 600, "end_pos": 602 }, { "start_pos": 605, "end_pos": 607 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A7H6-1", "uniprot_ac": "A0A8V1A7H6", "uniprot_id": "A0A8V1A7H6_CHICK", "mass": { "chemical_mass": 50880.0, "monoisotopic_mass": 50880.0 }, "refseq": { "ac": "NP_001384417", "name": "zinc finger MYND domain-containing protein 10", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384417" }, "gene_names": [ { "name": "ZMYND10", "type": "recommended", "evidence": [ { "id": "A0A8V1A7H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7H6" } ] }, { "name": "TUSC4", "type": "synonym", "evidence": [ { "id": "NP_001384417", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384417" } ] }, { "name": "ZMYND10", "type": "synonym", "evidence": [ { "id": "NP_001384417", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384417" } ] } ], "protein_names": [ { "name": "Zinc finger MYND domain-containing protein 10", "type": "recommended", "evidence": [ { "id": "A0A8V1A7H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7H6/entry#names_and_taxonomy" } ] }, { "name": "tumor suppressor candidate 4", "type": "synonym", "evidence": [ { "id": "NP_001384417", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384417" } ] }, { "name": "zinc finger MYND domain-containing protein 10", "type": "synonym", "evidence": [ { "id": "NP_001384417", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384417" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000251.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001384417", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384417" } ] }, { "annotation": "Plays a role in axonemal structure organization and motility. Involved in axonemal pre-assembly of inner and outer dynein arms (IDA and ODA, respectively) for proper axoneme building for cilia motility. May act by indirectly regulating transcription of dynein proteins.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7H6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7H6#function" }, { "database": "UniProtKB", "id": "ARBA00045527", "url": "https://www.uniprot.org/uniprotkb/ARBA00045527#function" }, { "database": "UniProtKB", "id": "A0A8V1AF75", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF75#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7H6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7H6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ZMYND10", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7H6", "locus": { "chromosome": "12", "start_pos": 1529199, "end_pos": 1540663, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028126", "url": "https://www.ensembl.org/id/ENSGALG00010028126" } ] } } ], "crossref": [ { "id": "A0A8V1A7H6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A7H6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000002131", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000002131", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "112529928", "url": "https://www.ncbi.nlm.nih.gov/gene/112529928", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002893", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002893", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009348", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009348", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052298", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052298", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "LIHEAYC", "url": "https://omabrowser.org/oma/group/LIHEAYC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1L1RSI4", "url": "https://www.orthodb.org/?gene=A0A1L1RSI4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A7H6", "url": "https://www.orthodb.org/?gene=A0A8V1A7H6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AF75", "url": "https://www.orthodb.org/?gene=A0A8V1AF75", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AHL0", "url": "https://www.orthodb.org/?gene=A0A8V1AHL0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AJF3", "url": "https://www.orthodb.org/?gene=A0A8V1AJF3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12991", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12991", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12991:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12991:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13244", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13244", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13244:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13244:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01753", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01753", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF06218", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06218", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001384417", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384417", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1L1RSI4", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RSI4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1L1RSI4-1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RSI4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A7H6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7H6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A7H6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7H6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AF75", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF75", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AF75-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF75-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHL0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHL0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHL0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHL0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJF3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJF3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJF3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJF3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAAEPLSPAEAEALVRALRGTELRDAGGKGWLRQHECVEKLNMHAILSASAGQEQLLIELLISHAKIPILIGELISAEVWKHKVFPVLCRLEDFHPSSTFPIYVVLHHEASIINLLETVFYHKEICESAEDSILDLIDYCHRKLTLLVARSASRQAATQQELHPEELAGLLSMQELQKQAEVMEFEISLKALSVLRFITDQVGSLPLSALTRMLNTHNLPCLLVELVEHCPWSCREAGKFKKFENGTWHVVPPEDQLKMTKLDGQVWLALLNLLLSPECQHKYHFDGFNKSQLLKLRAFLTDVLLDQLPNLVEMQRFLSHLAVTEPAPPKKDLVLEQVPVIWDHILKKNMGKWEAIAKHQVKHAFSPTEEELKLQARRWAQMYSLDMLEALAPDKPRCRVCGVEAAKRCSRCRNEWYCTRACQVQHWQKHRTACNLLAQAPGTAGTL", "length": 448, "header": "tr|A0A8V1A7H6-1|A0A8V1A7H6_CHICK Isoform 1 of Zinc finger MYND domain-containing protein 10 OS=Gallus gallus OX=9031 GN=ZMYND10 PE=3 SV=1 CANONICAL=A0A8V1A7H6-1" }, "isoforms": [ { "isoform_ac": "A0A1L1RSI4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7H6/entry#A0A1L1RSI4-1", "sequence": { "sequence": "MGGRIECVFFSEFHPTLGPKITYQVPEDFISRELFDTVQVYVITKPELQNKLITVTAMEKKLIGCPVCIEHKKYSRNALLFNLGFVCDARAKACALEPIVKKLAGYLTTLELESGFISNKESKQKLVPIMTILLEELNAKGKCTLPIDESNTIHLKVIEQRPDPQIVQEYDVPVFTQNKDDFFNSQWDLTTQQILPYIDGFRHVQKISAEADVELNLVRIAVQNLLYYGVVTLVSILQYSNVYCTTPKVQDVVDDKCLQEECLSYVTKPGHKRASLRDVFQLYCGLSPGTTVRDLISRYTLQLQRVDERRLIQFGLMKGLIRRLQKYPVKVARDERSHPARLYTGCHSYDEICCKTGGSGSMSVWRS", "length": 367, "header": "tr|A0A1L1RSI4-1|A0A1L1RSI4_CHICK Computationally mapped isoform of NPR2-like, GATOR1 complex subunit OS=Gallus gallus OX=9031 GN=ZMYND10 PE=3 SV=2 CANONICAL=A0A8V1A7H6-1" }, "locus": { "chromosome": "12", "start_pos": 1540610, "end_pos": 1537067, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068153.1", "url": "https://www.ensembl.org/id/ENSGALT00010068153.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041896.1", "url": "https://www.ensembl.org/id/ENSGALP00010041896.1" } ] } }, { "isoform_ac": "A0A8V1A7H6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7H6/entry#A0A8V1A7H6-1", "sequence": { "sequence": "MAAAEPLSPAEAEALVRALRGTELRDAGGKGWLRQHECVEKLNMHAILSASAGQEQLLIELLISHAKIPILIGELISAEVWKHKVFPVLCRLEDFHPSSTFPIYVVLHHEASIINLLETVFYHKEICESAEDSILDLIDYCHRKLTLLVARSASRQAATQQELHPEELAGLLSMQELQKQAEVMEFEISLKALSVLRFITDQVGSLPLSALTRMLNTHNLPCLLVELVEHCPWSCREAGKFKKFENGTWHVVPPEDQLKMTKLDGQVWLALLNLLLSPECQHKYHFDGFNKSQLLKLRAFLTDVLLDQLPNLVEMQRFLSHLAVTEPAPPKKDLVLEQVPVIWDHILKKNMGKWEAIAKHQVKHAFSPTEEELKLQARRWAQMYSLDMLEALAPDKPRCRVCGVEAAKRCSRCRNEWYCTRACQVQHWQKHRTACNLLAQAPGTAGTL", "length": 448, "header": "tr|A0A8V1A7H6-1|A0A8V1A7H6_CHICK Isoform 1 of Zinc finger MYND domain-containing protein 10 OS=Gallus gallus OX=9031 GN=ZMYND10 PE=3 SV=1 CANONICAL=A0A8V1A7H6-1" }, "locus": { "chromosome": "12", "start_pos": 1537767, "end_pos": 1529434, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068156.1", "url": "https://www.ensembl.org/id/ENSGALT00010068156.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041899.1", "url": "https://www.ensembl.org/id/ENSGALP00010041899.1" } ] } }, { "isoform_ac": "A0A8V1AF75-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7H6/entry#A0A8V1AF75-1", "sequence": { "sequence": "MHAILSASAGQEQLLIELLISHAKIPILIGELISAEVWKHKVFPVLCRLEDFHPSSTFPIYVVLHHEASIINLLETVFYHKEICESAEDSILDLIDYCHRKLTLLVARSASRQAATQQELHPEELAGLLSMQELQKQAEVMEFEISLKALSVLRFITDQVGSLPLSALTRMLNTHNLPCLLVELVEHCPWSCREAGKFKKFENGTWHVVPPEDQLKMTKLDGQVWLALLNLLLSPECQHKYHFDGFNKSQLLKLRAFLTDVLLDQLPNLVEMQRFLSHLAVTEPAPPKKDLVLEQVPVIWDHILKKNMGKWEAIAKHQVKHAFSPTEEELKLQARRWAQMYSLDMLEALAPDKPRCRVCGVEAAKRCSRCRNEWYCTRACQVQHWQKHRTACNLLAQAPGTAGTL", "length": 405, "header": "tr|A0A8V1AF75-1|A0A8V1AF75_CHICK Computationally mapped isoform of Zinc finger MYND domain-containing protein 10 OS=Gallus gallus OX=9031 GN=ZMYND10 PE=3 SV=1 CANONICAL=A0A8V1A7H6-1" }, "locus": { "chromosome": "12", "start_pos": 1537061, "end_pos": 1529434, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068155.1", "url": "https://www.ensembl.org/id/ENSGALT00010068155.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041898.1", "url": "https://www.ensembl.org/id/ENSGALP00010041898.1" } ] } }, { "isoform_ac": "A0A8V1AHL0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7H6/entry#A0A8V1AHL0-1", "sequence": { "sequence": "MHAILSASAGQEQLLIELLISHAKIPILIGELISAEVWKHKVFPVLCRLEDFHPSSTFPIYVVLHHEASIINLLETVFYHKEICESAEDSILDLIDYCHRKLTLLVARSASRQAATQQELHPEELAGLLSMQELQKQAEVMEFEISLKALSVLRFITDQVGSLPLSALTRMLNTHNLPCLLVELVEHCPWSCREAGKFKKFENGTWHVVPPEDQLKMTKLDGQVWLALLNLLLSPECQHKYHFDGFNKSQLLKLRAFLTDVLLDQLPNLVEMQRFLSHLAVTEPAPPKKDLVLEQACGDFFHLSCCSLLSLVTFSFSQVRPCRSCAPEEQPSTHSTVTPSLLETVCKERADCCPSSTAGMSVGSGRQCQRWGPHPRCYPSLHLCLWACVAPACAKDRQGEPAGGTRIGSILPSKQ", "length": 415, "header": "tr|A0A8V1AHL0-1|A0A8V1A7H6_CHICK Computationally mapped isoform of Zinc finger MYND domain-containing protein 10 OS=Gallus gallus OX=9031 GN=ZMYND10 PE=3 SV=1 CANONICAL=A0A8V1A7H6-1" }, "locus": { "chromosome": "12", "start_pos": 1537061, "end_pos": 1530517, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068154.1", "url": "https://www.ensembl.org/id/ENSGALT00010068154.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041897.1", "url": "https://www.ensembl.org/id/ENSGALP00010041897.1" } ] } }, { "isoform_ac": "A0A8V1AJF3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7H6/entry#A0A8V1AJF3-1", "sequence": { "sequence": "MGGRIECVFFSEFHPTLGPKITYQVPEDFISRELFDTVQVYVITKPELQNKLITVTAMEKKLIGCPVCIEHKKYSRNALLFNLGFVCDARAKACALEPIVKKLAGYLTTLELESGFISNKESKQKLVPIMTILLEELNAKGKCTLPIDESNTIHLKVIEQRPDPQIVQEYDVPVFTQNKDDFFNSQWDLTTQQILPYIDGFRHVQKISAEADVELNLVRIAVQNLLYYGVVTLVSILQVQDVVDDKCLQEECLSYVTKPGHKRASLRDVFQLYCGLSPGTTVRDLISRYTLQLQRVDERRLIQFGLMKGLIRRLQKYPVKVARDERSHPARLYTGCHSYDEICCKTGMSYKELDERLENDPNIIVCWK", "length": 368, "header": "tr|A0A8V1AJF3-1|A0A8V1A7H6_CHICK Computationally mapped isoform of Zinc finger MYND domain-containing protein 10 OS=Gallus gallus OX=9031 GN=ZMYND10 PE=3 SV=1 CANONICAL=A0A8V1A7H6-1" }, "locus": { "chromosome": "12", "start_pos": 1540610, "end_pos": 1537962, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068152.1", "url": "https://www.ensembl.org/id/ENSGALT00010068152.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041895.1", "url": "https://www.ensembl.org/id/ENSGALP00010041895.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A3L7HP06-1", "protein_name": "Zinc finger MYND domain-containing protein 10", "gene_name": "Zmynd10", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MGDLELLLPGEAEVLVRGLCSFPLPEMGSEGWSKQHESLEKLNMQAILDATVSQGEPIQELLVTHGKIPTLVEELIAVEMWKQKVFPVLCRLEDFKPHNTFPIYMVVHHEASIINLLETVFFHKEVCESADDKVLDLVDYCHRKLILLVARTGCGDPYEEERSQDSTPMQELQKQAEMMEFEISLKALSVLRYITDCVDSLSPSTLNRMLRTHNLPCLLVELLEHSPWCRREGGKLQQFENGRWQTVPPSEQQRLNKLDGQVWITLYNLLLSPEAQARYCLTSFVKGQLLKLQAFLTDTLLDQLPNLADLKGFLAHLALAETQPPKKDLVLEQIPEIWNQLERENKGKWQAIAKHQLQHVFSPSEKDLRRQAQRWAETYRLDVLEAIAPERPHCAYCQAEASKRCSRCQSVWYCCRDCQVKHWEKHGKTCVLAAQGDRAK", "length": 440 }, "evidence": [ { "id": "A0A8V1A7H6", "url": "https://omabrowser.org/oma/group/A0A8V1A7H6/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "E1BD65-1", "protein_name": "Zinc finger MYND domain-containing protein 10", "gene_name": "ZMYND10", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGDLELLLPGEADVLVRGLRSFQLRDMGSRGWNQQHENLEKLNMQAILDATASQGEPIQELLVTHGKIPTLVEELIAVEMWKQKVFPVLCKLEDFKPQNTFPIYMVLHHEASIINLLETVFFHKEVCESAEDTVLDLVDYCHRKLTLLVAQSGRGAPPEEESQYSSPMQELQKQAELMEFEIALKALSVLRYITDCVDSLSLSTLSRMLSTHNLPCLLVELLEHSPWSRREGGKLQQFESGRWQTVTPSEQQKLSKLDGQVWIALYNLLLSPEARARYCLTSFAKGQLLKLRAFLTDTLLDQLPNLADLQGFLAHLALTEAQPPKKDLVLEQIPEIWERLERENKGKWQAIAKHQLRHVFSPSEQDLRLQARRWAETYRLDVLEAVAPERPRCAYCSAEASKRCSRCQNEWYCCRECQVKHWEKHGKACVLAVQGDRAK", "length": 439 }, "evidence": [ { "id": "A0A8V1A7H6", "url": "https://omabrowser.org/oma/group/A0A8V1A7H6/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1SJ23-1", "protein_name": "Zinc finger MYND domain-containing protein 10", "gene_name": "ZMYND10", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGDLELLLPGEADVLVRGLRSFQIREMGSGGWNQQHENLEKLNMQAILDATASQGEPIQELLVTHGKIPTLVEELIAVEMWKQKVFPVLCKLEDFKPQNTFPIYMVIHHEASIINLLETVFFHKEVCESAEDTVLDLVDYCHRKLTLLVAHCGHDGPSEEEESQYSTPMQELQKQAELMEFEIALKALSVLRYITDCVDSLSLSTLSRMLSTHNLPCLLVELLEHSPWSRQEGGKLQQFESGRWQTVPPSEQQKLSKLDGQVWIALYNLLLSPEARAHYCLTSFAKGQLLKLQAFLTDTLLDQMPNLADLQGFLAHLALAEAQPPKKDLVLEQIPEIWERLEQENKGKWQAIAKHQLQHIFSTSEQDLRLQAQRWAETYRLDVLEAVAPERPRCAYCSAEASKRCSRCQNEWYCCRECQVKHWEKHGKSCVVAAQGDRAK", "length": 440 }, "evidence": [ { "id": "A0A8V1A7H6", "url": "https://omabrowser.org/oma/group/A0A8V1A7H6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O75800-1", "protein_name": "Zinc finger MYND domain-containing protein 10", "gene_name": "ZMYND10", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGDLELLLPGEAEVLVRGLRSFPLREMGSEGWNQQHENLEKLNMQAILDATVSQGEPIQELLVTHGKVPTLVEELIAVEMWKQKVFPVFCRVEDFKPQNTFPIYMVVHHEASIINLLETVFFHKEVCESAEDTVLDLVDYCHRKLTLLVAQSGCGGPPEGEGSQDSNPMQELQKQAELMEFEIALKALSVLRYITDCVDSLSLSTLSRMLSTHNLPCLLVELLEHSPWSRREGGKLQQFEGSRWHTVAPSEQQKLSKLDGQVWIALYNLLLSPEAQARYCLTSFAKGRLLKLRAFLTDTLLDQLPNLAHLQSFLAHLTLTETQPPKKDLVLEQIPEIWERLERENRGKWQAIAKHQLQHVFSPSEQDLRLQARRWAETYRLDVLEAVAPERPRCAYCSAEASKRCSRCQNEWYCCRECQVKHWEKHGKTCVLAAQGDRAK", "length": 440 }, "evidence": [ { "id": "A0A8V1A7H6", "url": "https://omabrowser.org/oma/group/A0A8V1A7H6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6AXZ5-1", "protein_name": "Zinc finger MYND domain-containing protein 10", "gene_name": "Zmynd10", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGDLELLLPGEAEVLVQGLHSFQLREMGSEGWSKQHENLEKLNMQAILDATVSQAEPIQELLVTHGKIPTLVEELIAVEMWKQKVFPVLCRLEDFKPQNTFPIYMVVHHEASIINLLETVFFHKEVCESADDTVLDLVDYCHRKLILLVARKGGGDLSEEERFQDSTPMQELQKQAEMMEFEISLKALSVLRYITDCMDSLSLSTLNRMLTTHNLPCLLVELLEHSPWSRREGGKLQHFESGRWQTVAPSEHQKLNKLDGQVWIALYNLLLSPEARTRYCLTNFAKGQLLKLQAFLTDTLLDQLPNLADLKSFLAHLALVETQPPKKDLVLEQIPEIWDRLERENKGKWQAIAKHQLQHVFSLSEKDLRQQAQRWAETYRLDVLEAVAPERPRCAYCSAEASKRCSRCQKVWYCCRECQVKHWEKHGKTCVLAAQGDRAK", "length": 440 }, "evidence": [ { "id": "A0A8V1A7H6", "url": "https://omabrowser.org/oma/group/A0A8V1A7H6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q99ML0-1", "protein_name": "Zinc finger MYND domain-containing protein 10", "gene_name": "Zmynd10", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGDLELLLPGEAEVLVRGLRSFQLREMGSEGWNKQHESLEKLNMQAILDATISQAEPIQELLINHGKIPTLVEELIAVEMWKQKVFPVLCRLEDFKPQNTFPIYMVVHHEASIINLLETVFFHKEVCESADDKVLDLVDYCHRKLILLVARKGGGDLSEEEQFQDSTPMQELQKQAEMMEFEISLKALSVLRYITDCVDSLSLSTLNRMLRTHNLPCLLVELLEHSPWSRRVGGKLQHFESGRWQTVAPSEQQKLNKLDGQVWIALYNLLLSPEARARYCLTSFAKGQLLKLQAFLTDTLLDQLPNLADLKGFLAHLSLAETQPPKKDLVLEQIPEIWDRLERENKGKWQAIAKHQLQHVFSLSEKDLRQQAQRWAETYRLDVLEAVAPERPRCGYCNAEASKRCSRCQNVWYCCRECQVKHWEKHGKTCVLAAQGDRAK", "length": 440 }, "evidence": [ { "id": "A0A8V1A7H6", "url": "https://omabrowser.org/oma/group/A0A8V1A7H6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VU41-1", "protein_name": "Zinc finger MYND domain-containing protein 10 homolog", "gene_name": "Zmynd10", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MVNFVHPEEMYLFVESIRPFEVREVGSPKWLEVHEMILGLSQQAALELSQNREEEVKEFLISRDKLRVLIHEAYCVTLWKTRVLPHLLEIDPNPQATFLIYTVLYHEAALVALLDVCLYHPSGCETLQESVLDLIDYCAQAISQVIGLVSMGYHENETKLDVDEAVLTELERQKRDFIYKIGLRCISVLNYIADNVTLFHLSAARRLLVTHDIPWLMADVLSFRPWQRKTSKGIQKFIDEKWTNVDDVTKIVKPEAQAWFCVRQLLLNPQIMENYAFNEARCKQLHKLLGLMHEPLLDQLPPLIELKVFLSRLTLSGNTAKTQPLLLEDIPQIQEELLKDVEENGGFYQIAQDQDSVFLSKNKENICALATRLSKAYGTDLLCELEQNMDDLKMGEAKDAGAGGDGDTDHTCATCQAKAKKKCACCKKVHYCSRDCQLKDWPQHKLVCLKT", "length": 451 }, "evidence": [ { "id": "A0A8V1A7H6", "url": "https://omabrowser.org/oma/group/A0A8V1A7H6/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "molecular adaptor activity", "id": "GO:0060090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060090", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7H6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7H6" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7H6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7H6" } ], "pmid": "" }, { "name": "protein folding chaperone", "id": "GO:0044183", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044183", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7H6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7H6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7H6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7H6" } ], "pmid": "" }, { "name": "apical plasma membrane", "id": "GO:0016324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016324", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7H6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7H6" } ], "pmid": "" }, { "name": "centriolar satellite", "id": "GO:0034451", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034451", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7H6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7H6" } ], "pmid": "" }, { "name": "dynein axonemal particle", "id": "GO:0120293", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120293", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7H6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7H6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "motile cilium assembly", "id": "GO:0044458", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044458", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7H6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7H6" } ], "pmid": "" }, { "name": "outer dynein arm assembly", "id": "GO:0036158", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036158", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7H6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7H6" } ], "pmid": "" }, { "name": "positive regulation of motile cilium assembly", "id": "GO:1905505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905505", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7H6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7H6" } ], "pmid": "" }, { "name": "inner dynein arm assembly", "id": "GO:0036159", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036159", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7H6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7H6" } ], "pmid": "" }, { "name": "negative regulation of TORC1 signaling", "id": "GO:1904262", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904262", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7H6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7H6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 246, "end_pos": 248, "annotation": "n_glycosylation_sequon" }, { "start_pos": 290, "end_pos": 292, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1A7H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7H6" }, { "id": "PS50865", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50865" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "MYND-type", "eco_id": "ECO_0000259", "start_pos": 399, "end_pos": 435, "start_aa": "Cys", "end_aa": "Cys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 246, "end_pos": 248 }, { "start_pos": 290, "end_pos": 292 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", 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"Protein" ] } ], "sequence": { "sequence": "MSAKQGGVTLLGGAQLSFLLVTNFSSVTSRQSTKVGCIASRRKIFGVEKACCDICNVVRMRMVSALGSARPRDRAAVLVLLLTAALVVGTQGACSAPPRFSFAELKEGYLHNRTFSTSDVVEYNCRPGYMRNTMARNTFICEKNRWKGSSNFCLPRPCSYPGEPMNGRLVEAEQFTFGSTANYSCDTGYRLIGNSQIRCVIKDGHVAWDGDVPTCEPIPCLPPPVIANGEHNGGHIELFTYGASVTYHCHADIRGRKHFSLVGDASIFCTTIDNVNGVWNKPAPECKEVSCREPHVEHGRLQSRYRAEYTYGDTIIFDCEFRYALLGSDTATCQEDGSWDPPPPQCQRSSCDDPPDVQNAVKARLAGNLFPIETVITYECKTGYEFSPGVVMEHISCQPDYTWTEVPPPCKRISCPNPATKTGMQISFWDRKDTYVFGDRVRIICDPGYVFKDRDDHVMLQCTNNGTWNRAAPECIPEPHCPKPAVDHGREAYNSKNDYTVGTKVRIECDEGYTLSTQQLVTCQADGNWFPSLPYCQKACGPPPQSTSGLNVNATSSSFPYGYRVEYSCAAGLSLIGDESLYCTSEDGVNLEWSGPAPECRVVHCPKPVVENGEMVTLRHTFPYGTSVSFYCKEGFMLRGSAESRCVADGTWQPALPKCQPVKCRAPTSKENLQFFPVKGEYEFKESLYFSCKLNNNAADRALTTCSTNGSWMPPPNCKTFYVRKKIDQIKETFDCGLPLAELRTLLEVQKLYLEIQKLEKELGAKGGRWWP", "length": 772, "header": "tr|A0A8V1AA32-1|A0A8V1AA32_CHICK Isoform 1 of Complement component 4 binding protein, secretory OS=Gallus gallus OX=9031 GN=C4BPS PE=1 SV=1 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gallus OX=9031 GN=C4BPS PE=1 SV=1 CANONICAL=A0A8V1AA32-1" }, "locus": { "chromosome": "26", "start_pos": 2676834, "end_pos": 2670972, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065826.1", "url": "https://www.ensembl.org/id/ENSGALT00010065826.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040092.1", "url": "https://www.ensembl.org/id/ENSGALP00010040092.1" } ] } }, { "isoform_ac": "A0A8V1AA32-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA32/entry#A0A8V1AA32-1", "sequence": { "sequence": 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"start_pos": 2676834, "end_pos": 2670146, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065828.1", "url": "https://www.ensembl.org/id/ENSGALT00010065828.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040094.1", "url": "https://www.ensembl.org/id/ENSGALP00010040094.1" } ] } }, { "isoform_ac": "A0A8V1ACX5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA32/entry#A0A8V1ACX5-1", "sequence": { "sequence": "MRMVSALGSARPRDRAAVLVLLLTAALVVGTQELKEGYLHNRTFSTSDVVEYNCRPGYMRNTMARNTFICEKNRWKGSSNFCLPRPCSYPGEPMNGRLVEAEQFTFGSTANYSCDTGYRLIGNSQIRCVIKDGHVAWDGDVPTCEPIPCLPPPVIANGEHNGGHIELFTYGASVTYHCHADIRGRKHFSLVGDASIFCTTIDNVNGVWNKPAPECKEVSCREPHVEHGRLQSRYRAEYTYGDTIIFDCEFRYALLGSDTATCQEDGSWDPPPPQCQRSSCDDPPDVQNAVKARLAGNLFPIETVITYECKTGYEFSPGVVMEHISCQPDYTWTEVPPPCKRISCPNPATKTGMQISFWDRKDTYVFGDRVRIICDPGYVFKDRDDHVMLQCTNNGTWNRAAPECIPEPHCPKPAVDHGREAYNSKNDYTVGTKVRIECDEGYTLSTQQLVTCQADGNWFPSLPYCQKACGPPPQSTSGLNVNATSSSFPYGYRVEYSCAAGLSLIGDESLYCTSEDGVNLEWSGPAPECRVVHCPKPVVENGEMVTLRHTFPYGTSVSFYCKEGFMLRGSAESRCVADGTWQPALPKCQPVKCRAPTSKENLQFFPVKGEYEFKESLYFSCKLNNNAADRALTTCSTNGSWMPPPNCKTFYVRKKIDQIKETFDCGLPLAELRTLLEVQKLYLEIQKLEKELGAKGGRWWP", "length": 701, "header": "tr|A0A8V1ACX5-1|A0A8V1ACX5_CHICK Computationally mapped isoform of Complement component 4 binding protein, secretory OS=Gallus gallus OX=9031 GN=C4BPS PE=1 SV=1 CANONICAL=A0A8V1AA32-1" }, "locus": { "chromosome": "26", "start_pos": 2676834, "end_pos": 2670569, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065827.1", "url": "https://www.ensembl.org/id/ENSGALT00010065827.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040093.1", "url": "https://www.ensembl.org/id/ENSGALP00010040093.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 112, "end_pos": 114, "annotation": "n_glycosylation_sequon" }, { "start_pos": 182, "end_pos": 184, "annotation": "n_glycosylation_sequon" }, { "start_pos": 23, "end_pos": 25, "annotation": "n_glycosylation_sequon" }, { "start_pos": 465, "end_pos": 467, "annotation": "n_glycosylation_sequon" }, { "start_pos": 553, "end_pos": 555, "annotation": "n_glycosylation_sequon" }, { "start_pos": 709, "end_pos": 711, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": 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"A0A8V1A7I3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7I3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MFSD12", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7I3", "locus": { "chromosome": "28", "start_pos": 1479525, "end_pos": 1472749, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028127", "url": "https://www.ensembl.org/id/ENSGALG00010028127" } ] } } ], "crossref": [ { "id": "A0A8V1A7I3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A7I3", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd17491", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17491", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "420074", "url": "https://www.ncbi.nlm.nih.gov/gene/420074", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR036259", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036259", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039672", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039672", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:420074", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420074", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GLYTAWM", "url": "https://omabrowser.org/oma/group/GLYTAWM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A7I3", "url": "https://www.orthodb.org/?gene=A0A8V1A7I3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ACF9", "url": "https://www.orthodb.org/?gene=A0A8V1ACF9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AJF7", "url": "https://www.orthodb.org/?gene=A0A8V1AJF7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11328", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11328", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11328:SF28", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11328:SF28", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13347", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13347", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1A7I3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7I3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A7I3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7I3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ACF9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ACF9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJF7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJF7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJF7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJF7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAEPALGAALPLRARLSFAAGHFLNDLCASLWFTYLLLYLHAVLGYSHGLAGGLLLAGQVADGLCTPLLGYEADRSAGCGRYGRRKSWHLAGTTCVLISFPFIFNPCLGCKEGTPQWAAFIYYLPFIVIFQFGWAATQISHLSLIPELVTSDHEKVELTAFRYAFTVMANITVYGLAWLLLNLQVDQPERTEHLGFQDVPVFRNLSLIVVGLGALFSLFFHLGTKEKLYPLGSVPQPKESTPLLQKEPTRSPRSLLVWKDWLLEPSFYQVAVLYMATRLIVNLSQTYIAMYLTNSLLLPKKYIATIPLVMYISGFLSSFLMKPVNKWIGRNLTYFVGILVILAFASWVSLSREMGAEIYGVAVLLGAGSATILVTSLSMTADLIGTNTHSSAFVYGAMSFTDKMANGLAVMLIQNLHPCPTELCCPACVSFYHWVMVLVTGGIAMAATVFLCCIMIWPIRVRFHGPGCSGRLQGDPHGRHVDRLSSLCFCCSWPQSWGCACGGKICPCLVVLLWEHMDVGGQRGLLRLLAAKWRAGGGLPSPSWGPTASAQYQLYL", "length": 556, "header": "tr|A0A8V1A7I3-1|A0A8V1A7I3_CHICK Isoform 1 of Major facilitator superfamily domain containing 12 OS=Gallus gallus OX=9031 GN=MFSD12 PE=3 SV=1 CANONICAL=A0A8V1A7I3-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A7I3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7I3/entry#A0A8V1A7I3-1", "sequence": { "sequence": "MAEPALGAALPLRARLSFAAGHFLNDLCASLWFTYLLLYLHAVLGYSHGLAGGLLLAGQVADGLCTPLLGYEADRSAGCGRYGRRKSWHLAGTTCVLISFPFIFNPCLGCKEGTPQWAAFIYYLPFIVIFQFGWAATQISHLSLIPELVTSDHEKVELTAFRYAFTVMANITVYGLAWLLLNLQVDQPERTEHLGFQDVPVFRNLSLIVVGLGALFSLFFHLGTKEKLYPLGSVPQPKESTPLLQKEPTRSPRSLLVWKDWLLEPSFYQVAVLYMATRLIVNLSQTYIAMYLTNSLLLPKKYIATIPLVMYISGFLSSFLMKPVNKWIGRNLTYFVGILVILAFASWVSLSREMGAEIYGVAVLLGAGSATILVTSLSMTADLIGTNTHSSAFVYGAMSFTDKMANGLAVMLIQNLHPCPTELCCPACVSFYHWVMVLVTGGIAMAATVFLCCIMIWPIRVRFHGPGCSGRLQGDPHGRHVDRLSSLCFCCSWPQSWGCACGGKICPCLVVLLWEHMDVGGQRGLLRLLAAKWRAGGGLPSPSWGPTASAQYQLYL", "length": 556, "header": "tr|A0A8V1A7I3-1|A0A8V1A7I3_CHICK Isoform 1 of Major facilitator superfamily domain containing 12 OS=Gallus gallus OX=9031 GN=MFSD12 PE=3 SV=1 CANONICAL=A0A8V1A7I3-1" }, "locus": { "chromosome": "28", "start_pos": 1478837, "end_pos": 1472805, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068161.1", "url": "https://www.ensembl.org/id/ENSGALT00010068161.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041904.1", "url": "https://www.ensembl.org/id/ENSGALP00010041904.1" } ] } }, { "isoform_ac": "A0A8V1ACF9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7I3/entry#A0A8V1ACF9-1", "sequence": { "sequence": "MAEPALGAALPLRARLSFAAGHFLNDLCASLWFTYLLLYLHAVLGYSHGLAGGLLLAGQVADGLCTPLLGYEADRSAGCGRYGRRKSWHLAGTTCVLISFPFIFNPCLGCKEGTPQWAAFIYYLPFIVIFQFGWAATQISHLSLIPELVTSDHEKVELTAFRYAFTVMANITVYGLAWLLLNLQVDQPERTEHLGFQDVPVFRNLSLIVVGLGALFSLFFHLGTKEKLYPLGSVPQPKESTPLLQKEPTRSPRSLLVWKDWLLEPSFYQVAVLYMATRLIVNLSQTYIAMYLTNSLLLPKKYIATIPLVMYISGFLSSFLMKPVNKWIGRNLTYFVGILVILAFASWVSLSREMGAEIYGVAVLLGAGSATILVTSLSMTADLIGTNTHSSAFVYGAMSFTDKMANGLAVMLIQNLHPCPTELCCPACVSFYHWVMVLVTGGIAMAATVFLCCIMIWPIRVRFHGPGCSGRLQGDPHDDIALQGLNEAGIQHHETESAEDRSLSSTVN", "length": 508, "header": "tr|A0A8V1ACF9-1|A0A8V1ACF9_CHICK Computationally mapped isoform of Major facilitator superfamily domain containing 12 OS=Gallus gallus OX=9031 GN=MFSD12 PE=3 SV=1 CANONICAL=A0A8V1A7I3-1" }, "locus": { "chromosome": "28", "start_pos": 1479109, "end_pos": 1472805, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068163.1", "url": "https://www.ensembl.org/id/ENSGALT00010068163.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041906.1", "url": "https://www.ensembl.org/id/ENSGALP00010041906.1" } ] } }, { "isoform_ac": "A0A8V1AJF7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7I3/entry#A0A8V1AJF7-1", "sequence": { "sequence": "MAEPALGAALPLRARLSFAAGHFLNDLCASLWFTYLLLYLHAVLGYSHGLAGGLLLAGQVADGLCTPLLGYEADRSAGCGRYGRRKSWHLAGTTCVLISFPFIFNPCLGCKEGTPQWAAFIYYLPFIVIFQFGWAATQISHLSLIPELVTSDHEKVELTAFRYAFTVMANITVYGLAWLLLNLQVDQPERTEHLGFQDVPVFRNLSLIVVGLGALFSLFFHLGTKEKLYPLGSVPQPKESTPLLQKEPTRSPRSLLVWKDWLLEPSFYQVAVLYMATRLIVNLSQTYIAMYLTNSLLLPKKYIATIPLVMYISGFLSSFLMKPVNKWIGRNLTYFVGILVILAFASWVSLSREMGAEIYGVAVLLGAGSATILVTSLSMTADLIGTNTDRTLLPCLCQLLSLGDGVGHWGYRHGCHCISVLHHDLAHPCPLP", "length": 432, "header": "tr|A0A8V1AJF7-1|A0A8V1A7I3_CHICK Computationally mapped isoform of Major facilitator superfamily domain containing 12 OS=Gallus gallus OX=9031 GN=MFSD12 PE=3 SV=1 CANONICAL=A0A8V1A7I3-1" }, "locus": { "chromosome": "28", "start_pos": 1479018, "end_pos": 1472805, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068157.1", "url": "https://www.ensembl.org/id/ENSGALT00010068157.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041900.1", "url": "https://www.ensembl.org/id/ENSGALP00010041900.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 547, "start_aa": "Thr", "end_pos": 547, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr547", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:420074", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420074", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1M4E3-1", "protein_name": "Major facilitator superfamily domain-containing protein 12", "gene_name": "Mfsd12", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSPPSGDAGPGPPRSLSLAARLSFAVGHFLNDLCAGMWFTYLLLFLHSVRGYSSRGAGLLLLLGQVADGLCTPLVGYEADRAACVRCGPRKAWHLAGTVCVLLSFPFIFSPCLGCGEATPEWAALLYYGPFIVIFQFGWAATQIAHLSLIPELTTSDHEKVELTALRYAFTVVANITVYGAAWLLLHLQGSAHGGQNISVGDQLGVQDVSVFRNLALLVVGVGAVFSLLFHLGTKESRRPQHRGIEPDEHSPLVAPVPQSLLLWKHWLQEPAFYQVGLLYMTTRLIVNLSQTYIAMYLTYSLSLPKKFIATIPLVMYLSGFFSSFLMKPINRRIGRNMTYFTGLLVILAFAAWVALADNLGVAVYGAALLLGAGCATILVTSLAMTADLIGPHTHSGAFVYGAMSFSDKVANGLAVMAVQSLHPCPSELCCGACIGFYHWVMTAVTGGVGVAAALALCSILIWPIRIRTRDPRDRP", "length": 476 }, "evidence": [ { "id": "A0A8V1A7I3", "url": "https://omabrowser.org/oma/group/A0A8V1A7I3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1S7R4-1", "protein_name": "Major facilitator superfamily domain-containing protein 12", "gene_name": "MFSD12", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGPGPPTAGAGAPPRPLSLVARLSYAVGHFLNDLCASMWFTYLLLYLHSVRAYSSRGAGLLLLLGQVADGLCTPLVGFEVDRAAGRCARFGPRKAWHLVGTICVLLSFPFIFSPCLGCGATTPEWAALLYYGPFIVIFQFGWAATQIAHLSLIPELVTNDHEKVELTALRYAFTVVANITVYGAAWLLLHLQGSPHMESTQDINDQLGVQDVPVFRNLSLLVVGIGAVFSLLFHLGTREGRRRQVEEPDEHGPLLAPATARPLLLWKHWLQEPAFYQVGLLYMSTRLIVNLSQTYMAMYLTYSLNLPKKFIATIPLVMYLSGFFSSFLMKPINKCIGRNMTYFVGLLVILAFAAWVALTNELGVAVYVAAVLLGTGCATILVTSLAMTADLIGPHTHSGAFVYGAMSFSDKVANGLAVMAIQSLHPCSLELCCRACVSFYHWVMVAVTGGVGVAATLCLCSLLIWPIRLQNWDSGAQP", "length": 478 }, "evidence": [ { "id": "A0A8V1A7I3", "url": "https://omabrowser.org/oma/group/A0A8V1A7I3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q3U481-1", "protein_name": "Major facilitator superfamily domain-containing protein 12", "gene_name": "Mfsd12", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSPPSDDAGPGPPRTLSLAARLSFAVGHFLNDLCAGMWFTYLLLFLHSVRGYSSRGAGLLLLLGQVADGLCTPLVGYEADRASCVRCGPRKAWHLAGTVCVLLSFPFIFSPCLGCGEATPEWAALLYYGPFIVVFQFGWAATQIAHLSLIPELVTSDHEKVELTALRYAFTVVANITVYGAAWLLLHLQGSAHGEQDISVGDQLGVQDVPVFRNLALLVVGVGAIFSLLFHLGTKEGHRSQHWGNEPNEHTPLVAPAAQPLLLWKHWLREPAFYQVGMLYMTTRLIVNLSQTYIAMYLTYSLSLPKKFIATIPLVMYLSGFFSSFLMKPVNRRIGRNMTYFTGLLVILAFAAWVALADNLGVAVYGAAVLLGAGCATILVTSLAMTADLIGPHTHSGAFVYGAMSFSDKVANGLAVMAVQSLHPCPSELCCGACISFYHWVMTAVTGGVGVAAALALCSLLIWPIRIRNRDPRDRP", "length": 476 }, "evidence": [ { "id": "A0A8V1A7I3", "url": "https://omabrowser.org/oma/group/A0A8V1A7I3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6NUT3-1", "protein_name": "Major facilitator superfamily domain-containing protein 12", "gene_name": "MFSD12", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGPGPPAAGAAPSPRPLSLVARLSYAVGHFLNDLCASMWFTYLLLYLHSVRAYSSRGAGLLLLLGQVADGLCTPLVGYEADRAASCCARYGPRKAWHLVGTVCVLLSFPFIFSPCLGCGAATPEWAALLYYGPFIVIFQFGWASTQISHLSLIPELVTNDHEKVELTALRYAFTVVANITVYGAAWLLLHLQGSSRVEPTQDISISDQLGGQDVPVFRNLSLLVVGVGAVFSLLFHLGTRERRRPHAEEPGEHTPLLAPATAQPLLLWKHWLREPAFYQVGILYMTTRLIVNLSQTYMAMYLTYSLHLPKKFIATIPLVMYLSGFLSSFLMKPINKCIGRNMTYFSGLLVILAFAAWVALAEGLGVAVYAAAVLLGAGCATILVTSLAMTADLIGPHTNSGAFVYGSMSFLDKVANGLAVMAIQSLHPCPSELCCRACVSFYHWAMVAVTGGVGVAAALCLCSLLLWPTRLRRWDRDARP", "length": 480 }, "evidence": [ { "id": "A0A8V1A7I3", "url": "https://omabrowser.org/oma/group/A0A8V1A7I3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "negative regulation of melanin biosynthetic process", "id": "GO:0048022", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048022", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7I3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7I3" } ], "pmid": "" }, { "name": "carbohydrate transport", "id": "GO:0008643", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008643", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7I3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7I3" } ], "pmid": "" }, { "name": "cysteine transmembrane transport", "id": "GO:1903712", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903712", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7I3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7I3" } ], "pmid": "" }, { "name": "regulation of melanin biosynthetic process", "id": "GO:0048021", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048021", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7I3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7I3" } ], "pmid": "" }, { "name": "pigment metabolic process involved in pigmentation", "id": "GO:0043474", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043474", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7I3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7I3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7I3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7I3" } ], "pmid": "" }, { "name": "lysosome", "id": "GO:0005764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005764", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7I3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7I3" } ], "pmid": "" }, { "name": "melanosome", "id": "GO:0042470", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042470", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7I3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7I3" } ], "pmid": "" }, { "name": "late endosome", "id": "GO:0005770", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005770", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7I3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7I3" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7I3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7I3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "symporter activity", "id": "GO:0015293", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015293", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7I3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7I3" } ], "pmid": "" }, { "name": "cysteine transmembrane transporter activity", "id": "GO:0033229", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033229", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7I3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7I3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 170, 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"length": 1076, "header": "tr|A0A8V1A7J0-1|A0A8V1A7J0_CHICK Isoform 1 of Pleckstrin homology and RUN domain containing M1 OS=Gallus gallus OX=9031 GN=PLEKHM1 PE=4 SV=1 CANONICAL=A0A8V1A7J0-1" }, "locus": { "chromosome": "27", "start_pos": 1250166, "end_pos": 1238426, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063473.1", "url": "https://www.ensembl.org/id/ENSGALT00010063473.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039184.1", "url": "https://www.ensembl.org/id/ENSGALP00010039184.1" } ] } }, { "isoform_ac": "A0A8V1ACI7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7J0/entry#A0A8V1ACI7-1", "sequence": { "sequence": "MHVGHTDPLIKKQLVSSIKALQKQYVSSDAVVTSDDGNANTLCCALEAVFVHGLKAKHIRTEAGGKGRKAGGRLPLPQPVFWALLKGITHRNIISELEQLIFITTDVGRCRAWLRLALNDGLVECYLKLLLRERSRLPEFYQPTALLLDAEECEFLLSYLQGLSSLTFQLSYKSAVLNEWTVTPLSLSGLCPVSELLEPPAAEPQRKASLGSISQSSGSDEIEIQPPALPICKAGDKPKRTSSSLSLNTTGSSQLSSSLGSDSVQPHCARSPERGDEPLSCDSDLGTATAEDLDRSLQEVLSEFRKAEPSFGAPSEQLIPAVLGCSPPPPEDTHPPPSPPPADACAAPQEEDSIPTPRRVDGGKEGRVVRSPAAKFLCSPLPGCSNRKSWISEDDFYRPSAGESDEIPADPNGFVPDGAGEGPTSGLLSALDLERPSPPPSQGPRLSPEREQKGFSVVHRRQMGLSNPFRGLLKLGSLERRGAMGIWKEFSCELSPLELRLFLDHEDRICVESFSLLRCESLALTHSDGRFELVFLGKKLCLRAPSRDEAEDWLDRIREALRKVRPQLEEEEWETLEYPEDGGDGCEPSAPLQYEAPGNGLDWTLSHKAELDAIKESILYADVDKTWVPFIFSLSLETLKCFKVRNNDKILSNSYGIETIQDILPDTSLGGPSFFKVITSKAVLKLRAESAQEAAAWRELVRAVLGSYLEGAEEALTLGGGLDGHSQVLLKSMVKENGFLLQYLVAIPVEKGLDSQSFICAGCSRQIGFSFAKPKLCAYSGLYYCDSCHRDDETVIPSRLIHNWDLSKRGVCRQALKFLTQICKQPLIDLKLVNESLYDHVERMRRIRRSREQLKLLGDYLSVCRSGALKELSKRLDHRNYLLECPHKYSVADLQQISDGAFEPFLLSLTHFASHHVYSCDLCTQRGFICQICGGSDIIFPFQLDSTARCKDCKTVFHRECYGSTASCPRCERRRRYRQEREEEEEEEEDGEEGSAGADPIEPAAIPKAAADEVPTSPKSSGRRCTTGCQPSSRGVTRRAHGQRGADEQRGLWGCSRPLPTPHRWDAVTL", "length": 1070, "header": "tr|A0A8V1ACI7-1|A0A8V1ACI7_CHICK Computationally mapped isoform of Pleckstrin homology and RUN domain containing M1 OS=Gallus gallus OX=9031 GN=PLEKHM1 PE=4 SV=2 CANONICAL=A0A8V1A7J0-1" }, "locus": { "chromosome": "27", "start_pos": 1250026, "end_pos": 1238426, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063470.1", "url": "https://www.ensembl.org/id/ENSGALT00010063470.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039181.1", "url": "https://www.ensembl.org/id/ENSGALP00010039181.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 430, "start_aa": "Thr", "end_pos": 430, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr430", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7J0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7J0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "lysosomal membrane", "id": "GO:0005765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005765", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7J0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7J0" } ], "pmid": "" }, { "name": "late endosome", "id": "GO:0005770", "url": 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"PS50003", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50003" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PH", "eco_id": "ECO_0000259", "start_pos": 477, "end_pos": 568, "start_aa": "Gly", "end_aa": "Arg", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1A7J0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7J0" }, { "id": "PS50826", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50826" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RUN", "eco_id": "ECO_0000259", "start_pos": 39, "end_pos": 181, "start_aa": "Thr", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 430 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 254, "end_pos": 256 }, { "start_pos": 840, "end_pos": 842 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { 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"phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A7K0-1", "uniprot_ac": "A0A8V1A7K0", "uniprot_id": "A0A8V1A7K0_CHICK", "mass": { "chemical_mass": 17100.0, "monoisotopic_mass": 17100.0 }, "refseq": { "ac": "XP_015148261", "name": "uncharacterized protein C3orf18 homolog isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015148261" }, "gene_names": [ { "name": "C3orf18", "type": "recommended", "evidence": [ { "id": "A0A8V1A7K0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7K0" } ] }, { "name": "C3orf18", "type": "synonym", "evidence": [ { "id": "XP_015148261", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015148261" } ] } ], "protein_names": [ { "name": "Chromosome 3 open reading frame 18", "type": "synonym", "evidence": [ { "id": "A0A8V1A7K0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7K0/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein C3orf18 homolog isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015148261", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015148261" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052543.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015148261.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015148261", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015148261" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7K0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7K0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "C3orf18", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7K0", "locus": { "chromosome": "12", "start_pos": 1835835, "end_pos": 1846962, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028136", "url": "https://www.ensembl.org/id/ENSGALG00010028136" } ] } } ], "crossref": [ { "id": "A0A8V1A7K0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A7K0", "database": "AlphaFoldDB", "categories": [] }, { "id": "415914", "url": "https://www.ncbi.nlm.nih.gov/gene/415914", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR042351", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042351", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:415914", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415914", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MAMVLYI", "url": "https://omabrowser.org/oma/group/MAMVLYI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A7K0", "url": "https://www.orthodb.org/?gene=A0A8V1A7K0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ACI0", "url": "https://www.orthodb.org/?gene=A0A8V1ACI0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AJH5", "url": "https://www.orthodb.org/?gene=A0A8V1AJH5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15868", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15868", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15868:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15868:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF27898", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27898", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015148261", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015148261", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1A7K0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7K0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A7K0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7K0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ACI0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACI0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ACI0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACI0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJH5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJH5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJH5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJH5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSSSSPSARDFYHSSSTTAKPDAGTTLDASVPETATVSPETTSFNSTKIPDVASNGPSMSAMLLSFGIITVIGLAVAMVLYIRKRKRLEKLRHQLMPMYNFDPTEEQDELEQELLEHGRDAASSQASQSKPFSKTEPAGIVGTVPGAGILLNRPQFSHT", "length": 159, "header": "tr|A0A8V1A7K0-1|A0A8V1A7K0_CHICK Isoform 1 of Chromosome 3 open reading frame 18 OS=Gallus gallus OX=9031 GN=C3orf18 PE=4 SV=1 CANONICAL=A0A8V1A7K0-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A7K0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7K0/entry#A0A8V1A7K0-1", "sequence": { "sequence": "MSSSSPSARDFYHSSSTTAKPDAGTTLDASVPETATVSPETTSFNSTKIPDVASNGPSMSAMLLSFGIITVIGLAVAMVLYIRKRKRLEKLRHQLMPMYNFDPTEEQDELEQELLEHGRDAASSQASQSKPFSKTEPAGIVGTVPGAGILLNRPQFSHT", "length": 159, "header": "tr|A0A8V1A7K0-1|A0A8V1A7K0_CHICK Isoform 1 of Chromosome 3 open reading frame 18 OS=Gallus gallus OX=9031 GN=C3orf18 PE=4 SV=1 CANONICAL=A0A8V1A7K0-1" }, "locus": { "chromosome": "12", "start_pos": 1844879, "end_pos": 1840116, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068181.1", "url": "https://www.ensembl.org/id/ENSGALT00010068181.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041924.1", "url": "https://www.ensembl.org/id/ENSGALP00010041924.1" } ] } }, { "isoform_ac": "A0A8V1ACI0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7K0/entry#A0A8V1ACI0-1", "sequence": { "sequence": "MSSSSPSARDFYHSSSTTAKPDAGTTLDASVPETATVSPETTSFNSTKIPDVASNGPSMSAMLLSFGIITVIGLAVAMVLYIRKRKRLEKLRHQLMPMYNFDPTEEQDELEQELLEHGRDAASSQASQSKILLTSQGALQRPSRLVFTDVANAINA", "length": 156, "header": "tr|A0A8V1ACI0-1|A0A8V1ACI0_CHICK Computationally mapped isoform of Chromosome 3 open reading frame 18 OS=Gallus gallus OX=9031 GN=C3orf18 PE=4 SV=1 CANONICAL=A0A8V1A7K0-1" }, "locus": { "chromosome": "12", "start_pos": 1844879, "end_pos": 1838773, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068183.1", "url": "https://www.ensembl.org/id/ENSGALT00010068183.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041926.1", "url": "https://www.ensembl.org/id/ENSGALP00010041926.1" } ] } }, { "isoform_ac": "A0A8V1AJH5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7K0/entry#A0A8V1AJH5-1", "sequence": { "sequence": "MSSSSPSARDFYHSSSTTAKPDAGTTLDASVPETATVSPETTSFNSTKIPDVASNGPSMSAMLLSFGIITVIGLAVAMVLYIRKRKRLEKLRHQLMPMYNFDPTEEQDELEQELLEHGRDAASSQASQSKFQEQEFSSTGLSFHILDTFRFC", "length": 152, "header": "tr|A0A8V1AJH5-1|A0A8V1A7K0_CHICK Computationally mapped isoform of Chromosome 3 open reading frame 18 OS=Gallus gallus OX=9031 GN=C3orf18 PE=4 SV=1 CANONICAL=A0A8V1A7K0-1" }, "locus": { "chromosome": "12", "start_pos": 1844879, "end_pos": 1838844, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068182.1", "url": "https://www.ensembl.org/id/ENSGALT00010068182.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041925.1", "url": "https://www.ensembl.org/id/ENSGALP00010041925.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:415914", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415914", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287B2Q2-1", "protein_name": "Chromosome 13 C3orf18 homolog", "gene_name": "C3orf18", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDSRISSAKGWFSSHPPTSEPDLEPATDGPASETTTLSPEATSFNDTRIPDVAGGTAGVGTMLLSFGIITVIGLAVAMVLYIRKKKRLEKLRHQLMPMYNFDPTEEQDELEQELLEHGRDAASMQAAAAVQAMQGKTTLPSQGPMQRPSRLVFTDVANAIHA", "length": 162 }, "evidence": [ { "id": "A0A8V1A7K0", "url": "https://omabrowser.org/oma/group/A0A8V1A7K0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "D4A9R5-1", "protein_name": "Similar to human chromosome 3 open reading frame 18", "gene_name": "C8h3orf18", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNSRVPATQSWFSSHPPTTEPDLEPATEGSTTETATLSPETTSFNDTRMPDMAGGTAGVGTMLLSFGIITVIGLAVAMVLYIRKKKRLEKLRHQLMPMYNFDPTEEQDELEQELLEHGRDAASLQAAASLQATQGKSTLPSQGPLQRPSRLVFTDVANAIHA", "length": 162 }, "evidence": [ { "id": "A0A8V1A7K0", "url": "https://omabrowser.org/oma/group/A0A8V1A7K0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3H8B4-1", "protein_name": "Uncharacterized protein C3orf18 homolog", "gene_name": "CUNH3orf18", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDSRVPATRSWFSGHPPTTEPDLEPATEGSTTETTTLSPETTSFNGTRIPDMAGGAVGVGTMLLSFGIITVIGLAVAMVLYIRKKKRLEKLRHQLMPMYNFDPTEEQDELEQELLEHGRDAASIQAAASLQATQGKSTLPSQGPLQRPSRLVFTDVANAIHA", "length": 162 }, "evidence": [ { "id": "A0A8V1A7K0", "url": "https://omabrowser.org/oma/group/A0A8V1A7K0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q8BGK9-1", "protein_name": "Uncharacterized protein C3orf18 homolog", "gene_name": "", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNSRVPATQSWFSSHLPTTEPDLEPATAAEGSTTETATLSPETTSFNDTRIPDVAGGAAGVGTMLLSFGIITVIGLAVAMVLYIRKKKRLEKLRHQLMPMYNFDPTEEQDELEQELLEHGRDAASMQAAASLQVTQGKSTLPSQGPLQRPSRLVFTDVANAIHA", "length": 164 }, "evidence": [ { "id": "A0A8V1A7K0", "url": "https://omabrowser.org/oma/group/A0A8V1A7K0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9UK00-1", "protein_name": "Uncharacterized protein C3orf18", "gene_name": "C3orf18", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNSRTASARGWFSSRPPTSESDLEPATDGPASETTTLSPEATTFNDTRIPDAAGGTAGVGTMLLSFGIITVIGLAVALVLYIRKKKRLEKLRHQLMPMYNFDPTEEQDELEQELLEHGRDAASVQAATSVQAMQGKTTLPSQGPLQRPSRLVFTDVANAIHA", "length": 162 }, "evidence": [ { "id": "A0A8V1A7K0", "url": "https://omabrowser.org/oma/group/A0A8V1A7K0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 45, "end_pos": 47, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 45, "end_pos": 47 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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"database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGCGAELRLRGSGGAQCDLVRLARGGESPALMGQTLRKWLPSTRTVCVETQEAAGSREPACVLCGRVDEDSSILGHKKELGGFYFHEFCAMFANDLCEHVEAGRMAQFSRKDLIRTVRQAEQTLCFVCGKTGATITCAALGCDRSFHLPCASEGQCVTLYIGKFRSLCWEHRPQQAVEAAPAQDTTCIICMEPVGDSRSYSTMVCPSCQHAWFHRACIQEQAMRAGIYCFQCPLCRDRDWFLRDMVTMGIRIPFRKPTWEDNNAYASLRIRHDRCDASSCLYPRGRERAEREGPWQLLLCSSCAAQGTHRRCSFLSQGTASWECNACAGEGTASGSGVDRAGPSTASQQGLPPLIGPITLESSSTSSTTSTTST", "length": 374, "header": "tr|A0A8V1A7K3-1|A0A8V1A7K3_CHICK Isoform 1 of PHD finger protein 7 OS=Gallus gallus OX=9031 GN=LOC101747452 PE=4 SV=1 CANONICAL=A0A8V1A7K3-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A7K3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7K3/entry#A0A8V1A7K3-1", "sequence": { "sequence": 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[], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7K3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7K3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7K3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7K3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1A7K3", "database": "UniProtKB", "url": 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"table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A7L4-1", "uniprot_ac": "A0A8V1A7L4", "uniprot_id": "A0A8V1A7L4_CHICK", "mass": { "chemical_mass": 57118.0, "monoisotopic_mass": 57118.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "A0A8V1A7L4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7L4/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7L4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7L4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7L4", "locus": {} } ], "crossref": [ { "id": "A0A8V1A7L4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A7L4", "database": "AlphaFoldDB", "categories": [] }, { "id": "A0A8V1A7L4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7L4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A7L4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7L4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ACL5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACL5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ACL5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACL5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "CHRPIADTGAAPPRCTHGRCRGCAVPTRRRTAGPGNCGDTAVWGHPVVSQRGSPKGCPKGCPQRAVPKRVSQRAVPKRVSQSAVPKGFPQKGVHKGCPKGCPQRVSPKGGPKGLSQRVSPKGGPKVLSPKGCPKGLSPKGGAPKGCPQRAVPKGVSQWAVPKGCPQKGVPKGVPKGCPQRGVPKGVPKGCPQRAVPKGVSQRVSQRAVPKRVSQRVPPNGVPKGVSQRVSQRAVPKRVSQRVPPKGVPKGCPQRAVPKGCPKGLSQRGFPKRVSTKGVPKGLSPKGCPKGCPKGLSPKGAPKGCPQRGVPKGCPQKGVPKGCPQRAVPKRVSQRVPPKGVPKGVSQSGVPKGCPQRAVPKRVSQRGVPMATSPQCPHGLSSTGCPKGVSPKGCSKGVSPKGCPQKGVPKGCPKGVSPKGCPQRVSPKGCPQRLSQRAVPKRVSQRAVPRGLSPKGVPKGCPTRVSPRPHPRSVPIVVSPRCSHRASQWWRPQRGVPIAVSPWCPHGGPTECPHGSVPMLGSLRCPQSGVPSAAPMVSPWRCPHGGVPMAVSL", "length": 552, "header": "tr|A0A8V1A7L4-1|A0A8V1A7L4_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1A7L4-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A7L4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7L4/entry#A0A8V1A7L4-1", "sequence": { "sequence": "CHRPIADTGAAPPRCTHGRCRGCAVPTRRRTAGPGNCGDTAVWGHPVVSQRGSPKGCPKGCPQRAVPKRVSQRAVPKRVSQSAVPKGFPQKGVHKGCPKGCPQRVSPKGGPKGLSQRVSPKGGPKVLSPKGCPKGLSPKGGAPKGCPQRAVPKGVSQWAVPKGCPQKGVPKGVPKGCPQRGVPKGVPKGCPQRAVPKGVSQRVSQRAVPKRVSQRVPPNGVPKGVSQRVSQRAVPKRVSQRVPPKGVPKGCPQRAVPKGCPKGLSQRGFPKRVSTKGVPKGLSPKGCPKGCPKGLSPKGAPKGCPQRGVPKGCPQKGVPKGCPQRAVPKRVSQRVPPKGVPKGVSQSGVPKGCPQRAVPKRVSQRGVPMATSPQCPHGLSSTGCPKGVSPKGCSKGVSPKGCPQKGVPKGCPKGVSPKGCPQRVSPKGCPQRLSQRAVPKRVSQRAVPRGLSPKGVPKGCPTRVSPRPHPRSVPIVVSPRCSHRASQWWRPQRGVPIAVSPWCPHGGPTECPHGSVPMLGSLRCPQSGVPSAAPMVSPWRCPHGGVPMAVSL", "length": 552, "header": "tr|A0A8V1A7L4-1|A0A8V1A7L4_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1A7L4-1" }, "locus": { "chromosome": "27", "start_pos": 1186583, "end_pos": 1182983, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063508.1", "url": "https://www.ensembl.org/id/ENSGALT00010063508.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039204.1", "url": "https://www.ensembl.org/id/ENSGALP00010039204.1" } ] } }, { "isoform_ac": "A0A8V1ACL5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7L4/entry#A0A8V1ACL5-1", "sequence": { "sequence": "MSRPHTQCHHPIFNDPTPYPMSTPHTQHHHPILNATTPHTLSPPHTHCPHPILNVTIPYPTSPPRLSPKGCPKGCPQTVSPKGCPKGCPKGLSPKGCPKGCPQRVSQRAVPKGLSQRGVPKGCPKGVSPKGCPQRVSPKGCPQRGVPKGVPKGCPQRVPQRAVPKGGSQRAVPKRVSQRAVPKGLSPKGCPKGCPQRVSPKGCPKAVSPKGVPKGLSPKGCPKGVSPWPHPHSVPMALSPWCPHRVSPWGAPKEMSQRAVPKGGAKGVPMVLSLWCPHRASPWGAPKGVSQRAVLNGVSQRGVPKGVFQRGVPKGLSPKGCPKGMSQRGFPKRVSAKGVPKGLSPKAVPKGCPQKSIPKSCPQRAVPKGCPKGLSHKGVPTATSPQCPHRCVPTVFPQSIPVVASPAWCPHSRVPMVSPWWPHRVSPRTAPLPSSPPNGAPTATSGDVGTARRWHRGAENGAGGGGGCGVGRGMGWVALGGDGRGL", "length": 486, "header": "tr|A0A8V1ACL5-1|A0A8V1ACL5_CHICK Computationally mapped isoform of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1A7L4-1" }, "locus": { "chromosome": "27", "start_pos": 1185790, "end_pos": 1182157, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063512.1", "url": "https://www.ensembl.org/id/ENSGALT00010063512.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039206.1", "url": "https://www.ensembl.org/id/ENSGALP00010039206.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { 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"sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A7M9-1", "uniprot_ac": "A0A8V1A7M9", "uniprot_id": "A0A8V1A7M9_CHICK", "mass": { "chemical_mass": 237299.0, "monoisotopic_mass": 237299.0 }, "refseq": {}, "gene_names": [ { "name": "DOCK3", "type": "recommended", "evidence": [ { "id": "A0A8V1A7M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M9" } ] } ], "protein_names": [ { "name": "Dedicator of cytokinesis 3", "type": "synonym", "evidence": [ { "id": "A0A8V1A7M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M9/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7M9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus 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"categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-9013149", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013149", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9013404", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013404", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9013408", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013408", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9032759", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9032759", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-983231", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983231", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1A7M9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A7M9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ACL1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACL1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ACL1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACL1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJJ7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJJ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJJ7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MWSPTEEEKYGVVICSFRGAVPQGLVLELGETVQILEKCEGWYRGVSIKKPNVKGIFPANYIHLKKAIVSNRGQYETVVPLEDSVVTEVTATLQEWAVLWKQLYVKHKVDLFYKLRHVMNELIDLRRQLLSGHLTQDQVREVKRHLTVRLDWGNEHLGLDLVPRKDFEVVDSDQISVSDLYKMHLSSRHSVQQSTSQVDTIRQRHGDACRMPVPHHFFLSLKSFTYNTIGEDTDVFFSLYDVREGKQISERFMVRLNKNGGPRNPEKIDRMCALFTDLSSKDMKRDLYIVAHVIRIGRMLLNDSKKGPPHLHYRRPYGCAVLSIMDVLQSISEIKEEKDFVLKVYTCNNENEWCQIHENIIRKSSTKYTAPSSNYGLIISLQLLRGDMEQVRRENPMIFNRGVSVTRKLGFPDVIMPGDIRNDLYLTLEKGDFERGGKSVQKNIEVTMYVLYADGEILKDCISLGSGEPSRSAYHSFVLYHNNSPRWGEIIKLPIPIDRFRGSHLRFEFRHCSTKDKGEKKLFGFAFTPLMRDDGTTLSDDIHELYVYKCDENSTFNNHALYLGLPCCKEDYNGCPNIPSSLIFQRSTKESFSVSTQLSSTKLTQNVDLLALLKWKAYPDRVMDILGRLRHVSGEEIVKFLQDILDTLFVVLDDNTEKYGLLVFQSLVFIINLLRDSKYFHFRPVMDTYIQKHFAGALAYKELIRCLKWYMDRSAELVRQDHIQEAMRALEYLFKFIVQSRILYSRATCGMEEEQFRSSIQELFQSIRFVLSLDSRSSETLIFTQAALLNSFPAIFDELLQMFTVQEVAEFVRGTLGSMPSTVHIGQSMDVVKLQSIARTVDSRLFSFSESRRILLPVVLHHIHLHLRQQKELLICSGILSSIFSIIKTSSLEGDVVEEVEMMVESLLDVLLQTLLTIMSKSQSQEAGEYVSCLLSLLRQMSDTHFQHLLDNFQSKDELKEFLLKIFCVFRNLMKMSVFPRDWMVMRLLTSNIIVTTVQYLSSALHKNFTETDFDFKVWNSYFSLAVLFINQPSLQLESATPAKRKKILDKYGDMRVMMAYELFSMWQNLGEHKIHFIPGMIGPFLGVTLVPQPEVRNIMIPIFHDMMDWEQRKNGNFKQVEAELIDKLDSLVSEGKGDENYRELFSLLLLEKIEQETWRETGISFVTSVTRLMERLLDYRDCMKGDETENKKIGCTVNLMNFYKSEINKEEMYIRYIHKLCDMHLQAENYTEAAFTLLLYCELLQWEDRPLREFLHYPSQSEWQRKEGLCRKIIHYFNKGKSWEFGIPLCRELAMQYESLYDYQSLSWIRKMEATYYDNIMEQQRLEPEFFRVGFYGRKFPFFLRNKEYVCRGHDYERLEAFQQRMLSEFPQAIAMQHPNHPDDSILQCDAQYLQIYAVTPIPDNIDVLQMDRVPDRIKSFYRVNNIRKFRYDRPFHKGPKDKDNEFKSLWIERTTLTLTHSLPGISRWFEVERRELVEVSPLENAIQVVENKNQELRTLISQYQHKQMHGNINLLSMCLNGVIDAAVNGGIARYQEAFFDKDYITKHPGDAEKITQLKELMQEQVHVLGVGLAVHEKFVHPEMRPLHKKLIDQFQMMRSSLYHELPGLDKLSPACSGSSTPRSNVLVSHGPMSPESIKLLHRHSPLNLLGSVRHSSSSLSSHTSSETGNLVILTDSSVGEAAEEMYHMQASPSTSSLSSTHSAPSQMINSAPSSARVLVKGGGLTTLEAEALYLPTEQIQHGRQPCKLPHAAPTNVPHLCPGGTTSRDKYRHTRELMMLLPTHRDRPSSAMYPTAIMENGQPPNFQRALMQQMIGPCKPCSDPNLSVAEKAVPAAPSSWSLDSGTREALPFLSAHVGSILAPPVPPRSLPHGHYSLHFDAFHHQLSDAPPALPARTLRKSPLHPIPASPTSPQSGLDGSNSTLSGSASSGVSSLSESNFGHSSEPPPRTDTMDSVPSQAWNTDEDLETPYLPVRYSLSEPDVLESLKSQPCRSHSAPSGVIPQDTLDPPALPPKPYHSRLPNIENEEGMIIEDDDKHRQLHRKVSQPVSGGKEEQARVAWEHGISEQ", "length": 2069, "header": "tr|A0A8V1A7M9-1|A0A8V1A7M9_CHICK Isoform 1 of Dedicator of cytokinesis 3 OS=Gallus gallus OX=9031 GN=DOCK3 PE=3 SV=1 CANONICAL=A0A8V1A7M9-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A7M9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M9/entry#A0A8V1A7M9-1", "sequence": { "sequence": "MWSPTEEEKYGVVICSFRGAVPQGLVLELGETVQILEKCEGWYRGVSIKKPNVKGIFPANYIHLKKAIVSNRGQYETVVPLEDSVVTEVTATLQEWAVLWKQLYVKHKVDLFYKLRHVMNELIDLRRQLLSGHLTQDQVREVKRHLTVRLDWGNEHLGLDLVPRKDFEVVDSDQISVSDLYKMHLSSRHSVQQSTSQVDTIRQRHGDACRMPVPHHFFLSLKSFTYNTIGEDTDVFFSLYDVREGKQISERFMVRLNKNGGPRNPEKIDRMCALFTDLSSKDMKRDLYIVAHVIRIGRMLLNDSKKGPPHLHYRRPYGCAVLSIMDVLQSISEIKEEKDFVLKVYTCNNENEWCQIHENIIRKSSTKYTAPSSNYGLIISLQLLRGDMEQVRRENPMIFNRGVSVTRKLGFPDVIMPGDIRNDLYLTLEKGDFERGGKSVQKNIEVTMYVLYADGEILKDCISLGSGEPSRSAYHSFVLYHNNSPRWGEIIKLPIPIDRFRGSHLRFEFRHCSTKDKGEKKLFGFAFTPLMRDDGTTLSDDIHELYVYKCDENSTFNNHALYLGLPCCKEDYNGCPNIPSSLIFQRSTKESFSVSTQLSSTKLTQNVDLLALLKWKAYPDRVMDILGRLRHVSGEEIVKFLQDILDTLFVVLDDNTEKYGLLVFQSLVFIINLLRDSKYFHFRPVMDTYIQKHFAGALAYKELIRCLKWYMDRSAELVRQDHIQEAMRALEYLFKFIVQSRILYSRATCGMEEEQFRSSIQELFQSIRFVLSLDSRSSETLIFTQAALLNSFPAIFDELLQMFTVQEVAEFVRGTLGSMPSTVHIGQSMDVVKLQSIARTVDSRLFSFSESRRILLPVVLHHIHLHLRQQKELLICSGILSSIFSIIKTSSLEGDVVEEVEMMVESLLDVLLQTLLTIMSKSQSQEAGEYVSCLLSLLRQMSDTHFQHLLDNFQSKDELKEFLLKIFCVFRNLMKMSVFPRDWMVMRLLTSNIIVTTVQYLSSALHKNFTETDFDFKVWNSYFSLAVLFINQPSLQLESATPAKRKKILDKYGDMRVMMAYELFSMWQNLGEHKIHFIPGMIGPFLGVTLVPQPEVRNIMIPIFHDMMDWEQRKNGNFKQVEAELIDKLDSLVSEGKGDENYRELFSLLLLEKIEQETWRETGISFVTSVTRLMERLLDYRDCMKGDETENKKIGCTVNLMNFYKSEINKEEMYIRYIHKLCDMHLQAENYTEAAFTLLLYCELLQWEDRPLREFLHYPSQSEWQRKEGLCRKIIHYFNKGKSWEFGIPLCRELAMQYESLYDYQSLSWIRKMEATYYDNIMEQQRLEPEFFRVGFYGRKFPFFLRNKEYVCRGHDYERLEAFQQRMLSEFPQAIAMQHPNHPDDSILQCDAQYLQIYAVTPIPDNIDVLQMDRVPDRIKSFYRVNNIRKFRYDRPFHKGPKDKDNEFKSLWIERTTLTLTHSLPGISRWFEVERRELVEVSPLENAIQVVENKNQELRTLISQYQHKQMHGNINLLSMCLNGVIDAAVNGGIARYQEAFFDKDYITKHPGDAEKITQLKELMQEQVHVLGVGLAVHEKFVHPEMRPLHKKLIDQFQMMRSSLYHELPGLDKLSPACSGSSTPRSNVLVSHGPMSPESIKLLHRHSPLNLLGSVRHSSSSLSSHTSSETGNLVILTDSSVGEAAEEMYHMQASPSTSSLSSTHSAPSQMINSAPSSARVLVKGGGLTTLEAEALYLPTEQIQHGRQPCKLPHAAPTNVPHLCPGGTTSRDKYRHTRELMMLLPTHRDRPSSAMYPTAIMENGQPPNFQRALMQQMIGPCKPCSDPNLSVAEKAVPAAPSSWSLDSGTREALPFLSAHVGSILAPPVPPRSLPHGHYSLHFDAFHHQLSDAPPALPARTLRKSPLHPIPASPTSPQSGLDGSNSTLSGSASSGVSSLSESNFGHSSEPPPRTDTMDSVPSQAWNTDEDLETPYLPVRYSLSEPDVLESLKSQPCRSHSAPSGVIPQDTLDPPALPPKPYHSRLPNIENEEGMIIEDDDKHRQLHRKVSQPVSGGKEEQARVAWEHGISEQ", "length": 2069, "header": "tr|A0A8V1A7M9-1|A0A8V1A7M9_CHICK Isoform 1 of Dedicator of cytokinesis 3 OS=Gallus gallus OX=9031 GN=DOCK3 PE=3 SV=1 CANONICAL=A0A8V1A7M9-1" }, "locus": { "chromosome": "12", "start_pos": 2313941, "end_pos": 2034690, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068211.1", "url": "https://www.ensembl.org/id/ENSGALT00010068211.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041954.1", "url": "https://www.ensembl.org/id/ENSGALP00010041954.1" } ] } }, { "isoform_ac": "A0A8V1ACL1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M9/entry#A0A8V1ACL1-1", "sequence": { "sequence": "MWSPTEEEKYGVVICSFRGAVPQGLVLELGETVQILEKCEGWYRGVSIKKPNVKGIFPANYIHLKKAIVSNRGQYETVVPLEDSVVTEVTATLQEWAVLWKQLYVKHKVDLFYKLRHVMNELIDLRRQLLSGHLTQDQVREVKRHLTVRLDWGNEHLGLDLVPRKDFEVVDSDQISVSDLYKMHLSSRHSVQQSTSQVDTIRQRHGDACRMPVPHHFFLSLKSFTYNTIGEDTDVFFSLYDVREGKQISERFMVRLNKNGGPRNPEKIDRMCALFTDLSSKDMKRDLYIVAHVIRIGRMLLNDSKKGPPHLHYRRPYGCAVLSIMDVLQSISEIKEEKDFVLKVYTCNNENEWCQIHENIIRKSSTKYTAPSSNYGLIISLQLLRGDMEQVRRENPMIFNRGVSVTRKLGFPDVIMPGDIRNDLYLTLEKGDFERGGKSVQKNIEVTMYVLYADGEILKDCISLGSGEPSRSAYHSFVLYHNNSPRWGEIIKLPIPIDRFRGSHLRFEFRHCSTKDKGEKKLFGFAFTPLMRDDGTTLSDDIHELYVYKCDENSTFNNHALYLGLPCCKEDYNGCPNIPSSLIFQRSTKESFSVSTQLSSTKLTQNVDLLALLKWKAYPDRVMDILGRLRHVSGEEIVKFLQDILDTLFVVLDDNTEKYGLLVFQSLVFIINLLRDSKYFHFRPVMDTYIQKHFAGALAYKELIRCLKWYMDRSAELVRQDHIQEAMRALEYLFKFIVQSRILYSRATCGMEEEQFRSSIQELFQSIRFVLSLDSRSSETLIFTQAALLNSFPAIFDELLQMFTVQEVAEFVRGTLGSMPSTVHIGQSMDVVKLQSIARTVDSRLFSFSESRRILLPVVLHHIHLHLRQQKELLICSGILSSIFSIIKTSSLEGDVVEEVEMMVESLLDVLLQTLLTIMSKSQSQEAVRGQRCPQCTAEITGEYVSCLLSLLRQMSDTHFQHLLDNFQSKDELKEFLLKIFCVFRNLMKMSVFPRDWMVMRLLTSNIIVTTVQYLSSALHKNFTETDFDFKVWNSYFSLAVLFINQPSLQLESATPAKRKKILDKYGDMRVMMAYELFSMWQNLGEHKIHFIPGMIGPFLGVTLVPQPEVRNIMIPIFHDMMDWEQRKNGNFKQVEAELIDKLDSLVSEGKGDENYRELFSLLTQLFGPYPSLLEKIEQETWRETGISFVTSVTRLMERLLDYRDCMKGDETENKKIGCTVNLMNFYKSEINKEEMYIRYIHKLCDMHLQAENYTEAAFTLLLYCELLQWEDRPLREFLHYPSQSEWQRKEGLCRKIIHYFNKGKSWEFGIPLCRELAMQYESLYDYQSLSWIRKMEATYYDNIMEQQRLEPEFFRVGFYGRKFPFFLRNKEYVCRGHDYERLEAFQQRMLSEFPQAIAMQHPNHPDDSILQCDAQYLQIYAVTPIPDNIDVLQMDRVPDRIKSFYRVNNIRKFRYDRPFHKGPKDKDNEFKSLWIERTTLTLTHSLPGISRWFEVERRELVEVSPLENAIQVVENKNQELRTLISQYQHKQMHGNINLLSMCLNGVIDAAVNGGIARYQEAFFDKDYITKHPGDAEKITQLKELMQEQVHVLGVGLAVHEKFVHPEMRPLHKKLIDQFQMMRSSLYHELPGLDKLSPACSGSSTPRSNVLVSHGPMSPESIKLLHRHSPLNLLGSVRHSSSSLSSHTSSETGNLVILTDSSVGEAAEEMYHMQASPSTSSLSSTHSAPSQMINSAPSSARDKYRHTRELMMLLPTHRDRPSSAMYPTAIMENGQPPNFQRALMQQMIGPCKPCSDPNLSVAEKAVPAAPSSWSLDSGTREALPFLSAHVGSILAPPVPPRSLPHGHYSLHFDAFHHQLSDAPPALPARTLRKSPLHPIPASPTSPQSGLDGSNSTLSGSASSGVSSLSESNFGHSSEPPPRTDTMDSVPSQAWNTDEDLETPYLPVRYSLSEPDVLESLKSQPCRSHSAPSGVIPQDTLDPPALPPKPYHSRLPNIENEEGMIIEDDDKHRQLHRKVSQPVSGGKEEQARVAWEHGISEQ", "length": 2041, "header": "tr|A0A8V1ACL1-1|A0A8V1ACL1_CHICK Computationally mapped isoform of Dedicator of cytokinesis 3 OS=Gallus gallus OX=9031 GN=DOCK3 PE=3 SV=1 CANONICAL=A0A8V1A7M9-1" }, "locus": { "chromosome": "12", "start_pos": 2313941, "end_pos": 2034690, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068213.1", "url": "https://www.ensembl.org/id/ENSGALT00010068213.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041956.1", "url": "https://www.ensembl.org/id/ENSGALP00010041956.1" } ] } }, { "isoform_ac": "A0A8V1AJJ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M9/entry#A0A8V1AJJ7-1", "sequence": { "sequence": "MWSPTEEEKYGVVICSFRGAVPQGLVLELGETVQILEKCEGWYRGVSIKKPNVKGIFPANYIHLKKAIVSNRGQYETVVPLEDSVVTEVTATLQEWAVLWKQLYVKHKVDLFYKLRHVMNELIDLRRQLLSGHLTQDQVREVKRHLTVRLDWGNEHLGLDLVPRKDFEVVDSDQISVSDLYKMHLSSRHSVQQSTSQVDTIRQRHGDACRMPVPHHFFLSLKSFTYNTIGEDTDVFFSLYDVREGKQISERFMVRLNKNGGPRNPEKIDRMCALFTDLSSKDMKRDLYIVAHVIRIGRMLLNDSKKGPPHLHYRRPYGCAVLSIMDVLQSISEIKEEKDFVLKVYTCNNENEWCQIHENIIRKSSTKYTAPSSNYGLIISLQLLRGDMEQVRRENPMIFNRGVSVTRKLGFPDVIMPGDIRNDLYLTLEKGDFERGGKSVQKNIEVTMYVLYADGEILKDCISLGSGEPSRSAYHSFVLYHNNSPRWGEIIKLPIPIDRFRGSHLRFEFRHCSTKDKGEKKLFGFAFTPLMRDDGTTLSDDIHELYVYKCDENSTFNNHALYLGLPCCKEDYNGCPNIPSSLIFQRSTKESFSVSTQLSSTKLTQNVDLLALLKWKAYPDRVMDILGRLRHVSGEEIVKFLQDILDTLFVVLDDNTEKYGLLVFQSLVFIINLLRDSKYFHFRPVMDTYIQKHFAGALAYKELIRCLKWYMDRSAELVRQDHIQEAMRALEYLFKFIVQSRILYSRATCGMEEEQFRSSIQELFQSIRFVLSLDSRSSETLIFTQAALLNSFPAIFDELLQMFTVQEVAEFVRGTLGSMPSTVHIGQSMDVVKLQSIARTVDSRLFSFSESRRILLPVVLHHIHLHLRQQKELLICSGILSSIFSIIKTSSLEGDVVEEVEMMVESLLDVLLQTLLTIMSKSQSQEAVRGQRCPQCTAEITGEYVSCLLSLLRQMSDTHFQHLLDNFQSKDELKEFLLKIFCVFRNLMKMSVFPRDWMVMRLLTSNIIVTTVQYLSSALHKNFTETDFDFKVWNSYFSLAVLFINQPSLQLESATPAKRKKILDKYGDMRVMMAYELFSMWQNLGEHKIHFIPGMIGPFLGVTLVPQPEVRNIMIPIFHDMMDWEQRKNGNFKQVEAELIDKLDSLVSEGKGDENYRELFSLLTQLFGPYPSLLEKIEQETWRETGISFVTSVTRLMERLLDYRDCMKGDETENKKIGCTVNLMNFYKSEINKEEMYIRYIHKLCDMHLQAENYTEAAFTLLLYCELLQWEDRPLREFLHYPSQSEWQRKEGLCRKIIHYFNKGKSWEFGIPLCRELAMQYESLYDYQSLSWIRKMEATYYDNIMEQQRLEPEFFRVGFYGRKFPFFLRNKEYVCRGHDYERLEAFQQRMLSEFPQAIAMQHPNHPDDSILQCDAQYLQIYAVTPIPDNIDVLQMDRVPDRIKSFYRVNNIRKFRYDRPFHKGPKDKDNEFKSLWIERTTLTLTHSLPGISRWFEVERRELVEVSPLENAIQVVENKNQELRTLISQYQHKQMHGNINLLSMCLNGVIDAAVNGGIARYQEAFFDKDYITKHPGDAEKITQLKELMQEQVHVLGVGLAVHEKFVHPEMRPLHKKLIDQFQMMRSSLYHELPGLDKLSPACSGSSTPRSNVLVSHGPMSPESIKLLHRHSPLNLLGSVRHSSSSLSSHTSSETGNLVILTDSSVGEAAEEMYHMQASPSTSSLSSTHSAPSQMINSAPSSARVLVKGGGLTTLEAEALYLPTEQIQHGRQPCKLPHAAPTNVPHLCPGGTTSRDKYRHTRELMMLLPTHRDRPSSAMYPTAIMENGQPPNFQRALMQQMIGPCKPCSDPNLSVAEKGHYSLHFDAFHHQLSDAPPALPARTLRKSPLHPIPASPTSPQSGLDGSNSTLSGSASSGVSSLSESNFGHSSEPPPRTDTMDSVPSQAWNTDEDLETPYLPVRYSLSEPDVLESLKSQPCRSHSAPSGVIPQDTLDPPALPPKPYHSRLPNIENEEGMIIEDDDKHRQLHRKVSQPVSGGKEEQARVAWEHGISEQ", "length": 2051, "header": "tr|A0A8V1AJJ7-1|A0A8V1A7M9_CHICK Computationally mapped isoform of Dedicator of cytokinesis 3 OS=Gallus gallus OX=9031 GN=DOCK3 PE=3 SV=1 CANONICAL=A0A8V1A7M9-1" }, "locus": { "chromosome": "12", "start_pos": 2313941, "end_pos": 2034690, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068212.1", "url": "https://www.ensembl.org/id/ENSGALT00010068212.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041955.1", "url": "https://www.ensembl.org/id/ENSGALP00010041955.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-9013149", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013149", "resource": "Reactome", "description": "RAC1 GTPase cycle" }, { "id": "R-GGA-9013404", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013404", "resource": "Reactome", "description": "RAC2 GTPase cycle" }, { "id": "R-GGA-9013408", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013408", "resource": "Reactome", "description": "RHOG GTPase cycle" }, { "id": "R-GGA-9032759", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9032759", "resource": "Reactome", "description": "NTRK2 activates RAC1" }, { "id": "R-GGA-983231", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983231", "resource": "Reactome", "description": "Factors involved in megakaryocyte development and platelet production" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7M9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M9" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7M9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M9" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7M9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "SH3 domain binding", "id": "GO:0017124", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017124", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7M9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M9" } ], "pmid": "" }, { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7M9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M9" } ], "pmid": "" }, { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7M9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "small GTPase-mediated signal transduction", "id": "GO:0007264", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007264", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7M9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1008, "end_pos": 1010, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1230, "end_pos": 1232, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1826, "end_pos": 1828, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1922, "end_pos": 1924, "annotation": "n_glycosylation_sequon" }, { "start_pos": 302, "end_pos": 304, "annotation": "n_glycosylation_sequon" }, { "start_pos": 482, "end_pos": 484, "annotation": "n_glycosylation_sequon" }, { "start_pos": 553, "end_pos": 555, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1A7M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M9" }, { "id": "PS51650", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51650" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2 DOCK-type", "eco_id": "ECO_0000259", "start_pos": 421, "end_pos": 599, "start_aa": "Arg", "end_aa": "Ser", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1A7M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M9" }, { "id": "PS51651", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51651" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DOCKER", "eco_id": "ECO_0000259", "start_pos": 1205, "end_pos": 1612, "start_aa": "Lys", "end_aa": "Lys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1A7M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M9" }, { "id": "PS50002", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50002" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SH3", "eco_id": "ECO_0000259", "start_pos": 6, "end_pos": 67, "start_aa": "Glu", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1008, "end_pos": 1010 }, { "start_pos": 1230, "end_pos": 1232 }, { "start_pos": 1826, "end_pos": 1828 }, { "start_pos": 1922, "end_pos": 1924 }, { "start_pos": 302, "end_pos": 304 }, { "start_pos": 482, "end_pos": 484 }, { "start_pos": 553, "end_pos": 555 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": 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This record is derived from a genomic sequence (NC_052559.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. 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"UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A7P9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A7P9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTSGSGHVDSKAELTTLLEQWEKEHGSGQDMVPILTRMSELIEKETEEYRKGDPDPFDDRHPGRADPECMLGHLLRILFKNDDFMNALVNAYVMTSREPPLNTAACRLLLDIMPGLETAVVFQEKEGIVENLFKWAREADQPLRTYATGLLGGAMENQDIAANYRDENSQLVALVLRRLRELQVTEMTTKQENKRPSPRKVPSDSLLPLDEEAVDMDYGEMAVDGEQEEVAGDMEISFHLDSSHKTSSRVNSATKLNDGGLRKSKSGKQHERDGFRKAKQKLGFSASEPERMFVELSNSSWSEMSPWVIGTNYTLYPLTPAIEQRLILQYLTPLGEYQELLPIFMQLGSRELMMYYIDLKRTNDVLLTFEALKHLASLLLHNKFATEFVAHGGVQKLLEIPRPSMAATGVSMCLYYLSYNQDAMERVCMHPHNVLSDVVNYTLWLMECSHASGCCHATMFFSICFSFRAVLELFDRHDGLRRLVNLISTLEILNLEDQGALLSDDEIFASRQTGKHTCMALRRYFEAHLAIKLEQVKQSLQRTEGGVLVHPQPPYKACSYTHEQIVEMMEFLIEYGPAQLYWEPAEVFLKLSCVQLMLQLISIACNWKTYYARNDTVRYALDVLAILTVVPKIQLQLAEPVDVLDEAGSTVSTVGISIILGVAEGEFFIHDAEIQKSALQIIINCVCGPDNRISSIGKFISGTPRRKLPQAPKSSEHTLAKMWNVVQSNNGIKVLLSLLSIKMPITDADQIRALACKALVGLSRSSTVRQIISKLPLFSSCQIQQLMKEPVLQDKRSEHVKFCKYAAELIERVSGKPLLIGTDVSLARLQKADVVAQSRITFPEKELLLLIRNHLISKGLGETASILTKEADLPMTAASHSSAFTPVAAAASPVALPRTPRIANGISARLSSHTSVGSAATSVHAQARPPVSQGPLALPGPSYASNSPLIGRISFVRERPSPCNGRKIRVLRQKSDHGAYSQSPAIKKQLDRHLPSPPTLDSIITEYLREQHARCKNPVATCPPFSLFTPHQCPEPKQRRQAPTNFTSRLTRRAAFPKYGGVDGGCFDRHLIFSRFRPISVFREANEDESGFTCCAFSARERFLMLGTCTGQLKLYNVFSGQEEASYNCHNSAITHLEPSRDGSLLLTSATWSQPLSALWGMKSVFDMKHSFPDDQYVEFSKHSQDRVIGTKGDIAHIYDIQTGNKLLTLFNPDLANNYKKNCATFNPTDDLVLNDGVLWDVRSAQAIHKFDKFNMTISGVFHPNGLEVIVNTEIWDLRTFHLLHTVPALDQCRVVFNYTGTVMYGAMLQADDEDELLEERMRSPFGSSFRTFNATDYKPIATIDVKRNIFDLCTDSKDCYLAVIENQGSMDSMNMDTVCRLYEVGRQRLAEDEEDEEEDQEEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDENNENAGEDGENDFSPSDDEELANLLEEGDEGEDEDSDADEEVELILGDTLITPTWKMT", "length": 1496, "header": "tr|A0A8V1A7P9-1|A0A8V1A7P9_CHICK Isoform 1 of DDB1- and CUL4-associated factor 1 OS=Gallus gallus OX=9031 GN=DCAF1 PE=1 SV=1 CANONICAL=A0A8V1A7P9-1" }, "isoforms": [ { "isoform_ac": "A0A1D5NW92-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9/entry#A0A1D5NW92-1", "sequence": { "sequence": "MTSGSGHVDSKAELTTLLEQWEKEHGSGQDMVPILTRMSELIEKETEEYRKGDPDPFDDRHPGRADPECMLGHLLRILFKNDDFMNALVNAYVMTSREPPLNTAACRLLLDIMPGLETAVVFQEKEGIVENLFKWAREADQPLRTYATGLLGGAMENQDIAANYRDENSQLVALVLRRLRELQVTEMTTKQENKRPSPRKVPSDSLLPLDEEAVDMDYGEMAVDGEQEEVAGDMEISFHLDSSHKTSSRVNSATKLNDGGLRKSKSGKQHERDGFRKAKQKLGFSASEPERMFVELSNSSWSEMSPWVIGTNYTLYPLTPAIEQRLILQYLTPLGEYQELLPIFMQLGSRELMMYYIDLKRTNDVLLTFEALKHLASLLLHNKFATEFVAHGGVQKLLEIPRPSMAATGVSMCLYYLSYNQDAMERVCMHPHNVLSDVVNYTLWLMECSHASGCCHATMFFSICFSFRAVLELFDRHDGLRRLVNLISTLEILNLEDQGALLSDDEIFASRQTGKHTCMALRRYFEAHLAIKLEQVKQSLQRTEGGVLVHPQPPYKACSYTHEQIVEMMEFLIEYGPAQLYWEPAEVFLKLSCVQLMLQLISIACNWKTYYARNDTVRYALDVLAILTVVPKIQLQLAEPVDVLDEAGSTVSTVGISIILGVAEGEFFIHDAEIQKSALQIIINCVCGPDNRISSIGKFISGTPRRKLPQAPKSSEHTLAKMWNVVQSNNGIKVLLSLLSIKMPITDADQIRALACKALVGLSRSSTVRQIISKLPLFSSCQIQQLMKEPVLQDKRSEHVKFCKYAAELIERVSGKPLLIGTDVSLARLQKADVVAQSRITFPEKELLLLIRNHLISKGLGETASILTKEADLPMTAASHSSAFTPVAAAASPVALPRTPRIANGISARLSSHTSVGSAATSVHAQARPPVSQGPLALPGPSYASNSPLIGRISFVRERPSPCNGRKIRVLRQKSDHGAYSQSPAIKKQLDRHLPSPPTLDSIITEYLREQHARCKNPVATCPPFSLFTPHQCPEPKQRRQAPTNFTSRLTRRAAFPKYGGVDGGCFDRHLIFSRFRPISVFREANEDESGFTCCAFSARERFLMLGTCTGQLKLYNVFSGQEEASYNCHNSAITHLEPSRDGSLLLTSATWSQPLSALWGMKSVFDMKHSFPDDQYVEFSKHSQDRVIGTKGDIAHIYDIQTGNKLLTLFNPDLANNYKKNCATFNPTDDLVLNDGVLWDVRSAQAIHKFDKFNMTISGVFHPNGLEVIVNTEIWDLRTFHLLHTVPALDQCRVVFNYTGTVMYGAMLQADDEDELLEERMRSPFGSSFRTFNATDYKPIATIDVKRNIFDLCTDSKDCYLAVIENQGSMDSMNMDTVCRLYEVGRQRLAEDEEDEEEDQEEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDENNENAGEDGENDFSPSDDEELANLLEEGDEGEDEDSDADEEVELILGDINCSIQ", "length": 1492, "header": "tr|A0A1D5NW92-1|A0A1D5NW92_CHICK Computationally mapped isoform of DDB1- and CUL4-associated factor 1 OS=Gallus gallus OX=9031 GN=DCAF1 PE=1 SV=2 CANONICAL=A0A8V1A7P9-1" }, "locus": { "chromosome": "12", "start_pos": 2376689, "end_pos": 2334511, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068230.1", "url": "https://www.ensembl.org/id/ENSGALT00010068230.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041973.1", "url": "https://www.ensembl.org/id/ENSGALP00010041973.1" } ] } }, { "isoform_ac": "A0A1D5PF43-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9/entry#A0A1D5PF43-1", "sequence": { "sequence": "MTSGSGHVDSKAELTTLLEQWEKEHGSGQDMVPILTRMSELIEKETEEYRKGDPDPFDDRHPGRADPECMLGHLLRILFKNDDFMNALVNAYVMTSREPPLNTAACRLLLDIMPGLETAVVFQEKEGIVENLFKWAREADQPLRTYATGLLGGAMENQDIAANYRDENSQLVALVLRRLRELQVTEMTTKQENKRPSPRKVPSDSLLPLDEEAVDMDYGEMAVDGEQEEVAGDMEISFHLDSSHKTSSRVNSATKLNDGGLRKSKSGKQHERDGFRKAKQKLGFSASEPERMFVELSNSSWSEMSPWVIGTNYTLYPLTPAIEQRLILQYLTPLGEYQELLPIFMQLGSRELMMYYIDLKRTNDVLLTFEALKHLASLLLHNKFATEFVAHGGVQKLLEIPRPSMAATGVSMCLYYLSYNQDAMERVCMHPHNVLSDVVNYTLWLMECSHASGCCHATMFFSICFSFRAVLELFDRHDGLRRLVNLISTLEILNLEDQGALLSDDEIFASRQTGKHTCMALRRYFEAHLAIKLEQVKQSLQRTEGGVLVHPQPPYKACSYTHEQIVEMMEFLIEYGPAQLYWEPAEVFLKLSCVQLMLQLISIACNWKTYYARNDTVRYALDVLAILTVVPKIQLQLAEPVDVLDEAGSTVSTVGISIILGVAEGEFFIHDAEIQKSALQIIINCVCGPDNRISSIGKFISGTPRRKLPQAPKSSEHTLAKMWNVVQSNNGIKVLLSLLSIKMPITDADQIRALACKALVGLSRSSTVRQIISKLPLFSSCQIQQLMKEPVLQDKRSEHVKFCKYAAELIERVSGKPLLIGTDVSLARLQKADVVAQSRITFPEKELLLLIRNHLISKGLGETASILTKEADLPMTAASHSSAFTPVAAAASPVALPRTPRIANGISARLSSHTSVGSAATSVHAQARPPVSQGPLALPGPSYASNSPLIGRISFVRERPSPCNGRKIRVLRQKSDHGAYSQSPAIKKQLDRHLPSPPTLDSIITEYLREQHARCKNPVATCPPFSLFTPHQCPEPKQRRQAPTNFTSRLTRRAAFPKYGGVDGGCFDRHLIFSRFRPISVFREANEDESGFTCCAFSARERFLMLGTCTGQLKLYNVFSGQEEASYNCHNSAITHLEPSRDGSLLLTSATWSQPLSALWGMKSVFDMKHSFPDDQYVEFSKHSQDRVIGTKGDIAHIYDIQTGNKLLTLFNPDLANNYKKNCATFNPTDDLVLNDGVLWDVRSAQAIHKFDKFNMTISGVFHPNGLEVIVNTEIWDLRTFHLLHTVPALDQCRVVFNYTGTVMYGAMLQADDEDELLEERMRSPFGSSFRTFNATDYKPIATIDVKRNIFDLCTDSKDCYLAVIENQGSMDSMNMDTVCRLYEVGRQRLAEDEEDEEEDQINHFEL", "length": 1407, "header": "tr|A0A1D5PF43-1|A0A1D5PF43_CHICK Computationally mapped isoform of DDB1- and CUL4-associated factor 1 OS=Gallus gallus OX=9031 GN=DCAF1 PE=1 SV=2 CANONICAL=A0A8V1A7P9-1" }, "locus": { "chromosome": "12", "start_pos": 2376689, "end_pos": 2348357, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068228.1", "url": "https://www.ensembl.org/id/ENSGALT00010068228.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041971.1", "url": "https://www.ensembl.org/id/ENSGALP00010041971.1" } ] } }, { "isoform_ac": "A0A1D5PYE6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9/entry#A0A1D5PYE6-1", "sequence": { "sequence": "MTSGSGHVDSKAELTTLLEQWEKEHGSGQDMVPILTRMSELIEKETEEYRKGDPDPFDDRHPGRADPECMLGHLLRILFKNDDFMNALVNAYVMTSREPPLNTAACRLLLDIMPGLETAVVFQEKEGIVENLFKWAREADQPLRTYATGLLGGAMENQDIAANYRDENSQLLLPIFMQLGSRELMMYYIDLKRTNDVLLTFEALKHLASLLLHNKFATEFVAHGGVQKLLEIPRPSMAATGVSMCLYYLSYNQDAMERVCMHPHNVLSDVVNYTLWLMECSHASGCCHATMFFSICFSFRAVLELFDRHDGLRRLVNLISTLEILNLEDQGALLSDDEIFASRQTGKHTCMALRRYFEAHLAIKLEQVKQSLQRTEGGVLVHPQPPYKACSYTHEQIVEMMEFLIEYGPAQLYWEPAEVFLKLSCVQLMLQLISIACNWKTYYARNDTVRYALDVLAILTVVPKIQLQLAEPVDVLDEAGSTVSTVGISIILGVAEGEFFIHDAEIQKSALQIIINCVCGPDNRISSIGKFISGTPRRKLPQAPKSSEHTLAKMWNVVQSNNGIKVLLSLLSIKMPITDADQIRALACKALVGLSRSSTVRQIISKLPLFSSCQIQQLMKEPVLQDKRSEHVKFCKYAAELIERVSGKPLLIGTDVSLARLQKADVVAQSRITFPEKELLLLIRNHLISKGLGETASILTKEADLPMTAASHSSAFTPVAAAASPVALPRTPRIANGISARLSSHTSVGSAATSVHAQARPPVSQGPLALPGPSYASNSPLIGRISFVRERPSPCNGRKIRVLRQKSDHGAYSQSPAIKKQLDRHLPSPPTLDSIITEYLREQHARCKNPVATCPPFSLFTPHQCPEPKQRRQAPTNFTSRLTRRAAFPKYGGVDGGCFDRHLIFSRFRPISVFREANEDESGFTCCAFSARERFLMLGTCTGQLKLYNVFSGQEEASYNCHNSAITHLEPSRDGSLLLTSATWSQPLSALWGMKSVFDMKHSFPDDQYVEFSKHSQDRVIGTKGDIAHIYDIQTGNKLLTLFNPDLANNYKKNCATFNPTDDLVLNDGVLWDVRSAQAIHKFDKFNMTISGVFHPNGLEVIVNTEIWDLRTFHLLHTVPALDQCRVVFNYTGTVMYGAMLQADDEDELLEERMRSPFGSSFRTFNATDYKPIATIDVKRNIFDLCTDSKDCYLAVIENQGSMDSMNMDTVCRLYEVGRQRLAEDEEDEEEDQEEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDENNENAGEDGENDFSPSDDEELANLLEEGDEGEDEDSDADEEVELILGDTDSSDNSDLEDDIILTLNE", "length": 1337, "header": "tr|A0A1D5PYE6-1|A0A1D5PYE6_CHICK Computationally mapped isoform of DDB1- and CUL4-associated factor 1 OS=Gallus gallus OX=9031 GN=DCAF1 PE=1 SV=1 CANONICAL=A0A8V1A7P9-1" }, "locus": { "chromosome": "12", "start_pos": 2376689, "end_pos": 2333535, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068231.1", "url": "https://www.ensembl.org/id/ENSGALT00010068231.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041974.1", "url": "https://www.ensembl.org/id/ENSGALP00010041974.1" } ] } }, { "isoform_ac": "A0A8V1A7P9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9/entry#A0A8V1A7P9-1", "sequence": { "sequence": "MTSGSGHVDSKAELTTLLEQWEKEHGSGQDMVPILTRMSELIEKETEEYRKGDPDPFDDRHPGRADPECMLGHLLRILFKNDDFMNALVNAYVMTSREPPLNTAACRLLLDIMPGLETAVVFQEKEGIVENLFKWAREADQPLRTYATGLLGGAMENQDIAANYRDENSQLVALVLRRLRELQVTEMTTKQENKRPSPRKVPSDSLLPLDEEAVDMDYGEMAVDGEQEEVAGDMEISFHLDSSHKTSSRVNSATKLNDGGLRKSKSGKQHERDGFRKAKQKLGFSASEPERMFVELSNSSWSEMSPWVIGTNYTLYPLTPAIEQRLILQYLTPLGEYQELLPIFMQLGSRELMMYYIDLKRTNDVLLTFEALKHLASLLLHNKFATEFVAHGGVQKLLEIPRPSMAATGVSMCLYYLSYNQDAMERVCMHPHNVLSDVVNYTLWLMECSHASGCCHATMFFSICFSFRAVLELFDRHDGLRRLVNLISTLEILNLEDQGALLSDDEIFASRQTGKHTCMALRRYFEAHLAIKLEQVKQSLQRTEGGVLVHPQPPYKACSYTHEQIVEMMEFLIEYGPAQLYWEPAEVFLKLSCVQLMLQLISIACNWKTYYARNDTVRYALDVLAILTVVPKIQLQLAEPVDVLDEAGSTVSTVGISIILGVAEGEFFIHDAEIQKSALQIIINCVCGPDNRISSIGKFISGTPRRKLPQAPKSSEHTLAKMWNVVQSNNGIKVLLSLLSIKMPITDADQIRALACKALVGLSRSSTVRQIISKLPLFSSCQIQQLMKEPVLQDKRSEHVKFCKYAAELIERVSGKPLLIGTDVSLARLQKADVVAQSRITFPEKELLLLIRNHLISKGLGETASILTKEADLPMTAASHSSAFTPVAAAASPVALPRTPRIANGISARLSSHTSVGSAATSVHAQARPPVSQGPLALPGPSYASNSPLIGRISFVRERPSPCNGRKIRVLRQKSDHGAYSQSPAIKKQLDRHLPSPPTLDSIITEYLREQHARCKNPVATCPPFSLFTPHQCPEPKQRRQAPTNFTSRLTRRAAFPKYGGVDGGCFDRHLIFSRFRPISVFREANEDESGFTCCAFSARERFLMLGTCTGQLKLYNVFSGQEEASYNCHNSAITHLEPSRDGSLLLTSATWSQPLSALWGMKSVFDMKHSFPDDQYVEFSKHSQDRVIGTKGDIAHIYDIQTGNKLLTLFNPDLANNYKKNCATFNPTDDLVLNDGVLWDVRSAQAIHKFDKFNMTISGVFHPNGLEVIVNTEIWDLRTFHLLHTVPALDQCRVVFNYTGTVMYGAMLQADDEDELLEERMRSPFGSSFRTFNATDYKPIATIDVKRNIFDLCTDSKDCYLAVIENQGSMDSMNMDTVCRLYEVGRQRLAEDEEDEEEDQEEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDENNENAGEDGENDFSPSDDEELANLLEEGDEGEDEDSDADEEVELILGDTLITPTWKMT", "length": 1496, "header": "tr|A0A8V1A7P9-1|A0A8V1A7P9_CHICK Isoform 1 of DDB1- and CUL4-associated factor 1 OS=Gallus gallus OX=9031 GN=DCAF1 PE=1 SV=1 CANONICAL=A0A8V1A7P9-1" }, "locus": { "chromosome": "12", "start_pos": 2376689, "end_pos": 2333555, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068232.1", "url": "https://www.ensembl.org/id/ENSGALT00010068232.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041975.1", "url": "https://www.ensembl.org/id/ENSGALP00010041975.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-GGA-983168", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983168", "resource": "Reactome", "description": "Antigen processing: Ubiquitination & Proteasome degradation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7P9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7P9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ], "pmid": "" }, { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7P9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ], "pmid": "" }, { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7P9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ], "pmid": "" }, { "name": "positive regulation of protein catabolic process", "id": "GO:0045732", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045732", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7P9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ], "pmid": "" }, { "name": "cell competition in a multicellular organism", "id": "GO:0035212", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035212", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7P9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ], "pmid": "" }, { "name": "chromatin organization", "id": "GO:0006325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006325", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7P9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7P9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ], "pmid": "" }, { "name": "nuclear estrogen receptor binding", "id": "GO:0030331", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030331", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7P9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ], "pmid": "" }, { "name": "ubiquitin-like ligase-substrate adaptor activity", "id": "GO:1990756", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990756", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7P9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ], "pmid": "" }, { "name": "histone H2AT120 kinase activity", "id": "GO:1990244", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990244", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7P9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ], "pmid": "" }, { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7P9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7P9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7P9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7P9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ], "pmid": 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"A0A8V0ZUU8-1", "A0A8V1AG70-1", "F1NA68-1", "F1NLR7-1", "A0A8V0Y6K1-1", "A0A8V0XS42-1", "A0A8V0YRN4-1", "A0A8V0YFP8-1", "A0A8V1A7P9-1", "A0A1D5PRN8-1", "A0A3Q3AAD7-1", "A0A3Q2TWZ8-1", "A0A8V0XBZ0-1", "A0A8V0XFX2-1", "A0A8V0YFL1-1", "A0A8V0YTL9-1", "A0A8V0YMB3-1", "A0A8V0X2Y2-1", "A0A8V0XCY6-1", "A0A3Q2UI62-1", "A0A8V0Y241-1", "A0A8V0Z8G2-1", "A0A8V1ABR8-1", "A0A8V1AP60-1", "A0A8V0YZM1-1", "A0A8V0ZB38-1", "A0A8V0Z466-1", "A0A8V0ZA06-1", "A0A8V1AMQ2-1", "A0A8V0ZGY3-1", "A0A8V0ZQJ2-1", "A0A8V0ZYU6-1", "A0A8V1A513-1", "A0A8V0XE48-1", "A0A8V0XKG0-1" ], "evidence": [ { "id": "46608", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/46608" } ] }, { "id": "R-GGA-983140", "name": "Transfer of Ub from E2 to substrate and release of E2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0X324-1", "A0A8V0XEM6-1", "A0A8V0XJC4-1", "A0A8V0XQR1-1", "A0A8V1AC19-1", "A0A8V1AC55-1", "A0A8V1AKB8-1", "A0A8V1ALH0-1", "F1NL19-1", "F1NRC6-1", "F1NTZ8-1", "A0A8V0YHL7-1", "A0A8V0YPW4-1", "A0A8V0YRM6-1", "A0A8V0YV22-1", "A0A8V0YVP3-1", "A0A8V0Z2L5-1", "F1NL77-1", "E1C982-1", "A0A3Q2UC96-1", "Q5ZKX6-1", "Z4YJC3-1", "A0A8V0XQU7-1", "A0A8V0Y5C9-1", "A0A8V1AL09-1", "A0A8V1AML5-1", "A0A8V1AP69-1", "F1NVY8-1", "R4GIV8-1", "A0A8V0ZJ49-1", "A0A8V0ZJV9-1", "A0A8V0ZL18-1", "A0A8V0ZM17-1", "A0A8V0ZSH4-1", "A0A8V0ZVX3-1", "A0A8V0ZW26-1", "A0A8V1A0Z6-1", "A0A8V0ZZH3-1", "A0A8V1A052-1", "A0A8V1A0X2-1", "A0A8V1A1I4-1", "A0A8V1A2W7-1", "A0A8V1A5P4-1", "A0A8V1A7T1-1", "A0A8V0XTY5-1", "A0A8V0Y5B5-1", "A0A8V0YL05-1", "A0A8V0Z082-1", "A0A8V0ZS27-1", "A0A8V1A9M0-1", "E1BZ35-1", "E1C3Q9-1", "F1NC08-1", "F1P2G0-1", "A0A8V0YY10-1", "A0A8V0YYC5-1", "A0A8V0Z1W7-1", "A0A8V0Z4C8-1", "A0A8V0Z596-1", "A0A1D5P284-1", "A0A8V0ZF21-1", "A0A3Q2U2G8-1", "A0A8V1A4H7-1", "A0A8V1A1N8-1", "A0A8V1A233-1", "A0A8V1A7P9-1", "A0A8V1ACU3-1", "A0A8V0ZSA3-1", "E1C656-1", "A0A8V0Y0Q7-1", "A0A8V0Y059-1", "A0A8V0Y5C7-1", "A0A8V0YCS7-1", "A0A8V0YDQ1-1", "A0A8V0YFD9-1", "A0A8V0YGF4-1", "A0A8V0YJK8-1", "A0A8V0YLY7-1", "A0A1D5NVE2-1", "A0A8V0ZKK3-1", "A0A8V0ZKQ3-1" ], "evidence": [ { "id": "R-GGA-983140", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983140" } ] }, { "id": "R-GGA-983147", "name": "Release of E3 from polyubiquitinated substrate", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XEM6-1", "A0A8V0XJC4-1", "A0A8V1AC55-1", "A0A8V1AKB8-1", "A0A8V1ALH0-1", "F1NRC6-1", "F1NTZ8-1", "A0A8V0YHL7-1", "A0A8V0YRM6-1", "A0A8V0YV22-1", "A0A8V0YVP3-1", "A0A8V0Z2L5-1", "F1NL77-1", "E1C982-1", "A0A3Q2UC96-1", "Z4YJC3-1", "A0A8V0XQU7-1", "A0A8V0Y5C9-1", "A0A8V1AL09-1", "A0A8V1AML5-1", "A0A8V1AP69-1", "F1NVY8-1", "A0A8V0ZJ49-1", "A0A8V0ZJV9-1", "A0A8V0ZL18-1", "A0A8V0ZM17-1", "A0A8V0ZSH4-1", "A0A8V0ZVX3-1", "A0A8V0ZW26-1", "A0A8V1A0Z6-1", "A0A8V0ZZH3-1", "A0A8V1A0X2-1", "A0A8V1A2W7-1", "A0A8V1A7T1-1", "A0A8V0XTY5-1", "A0A8V0Y5B5-1", "A0A8V0YL05-1", "A0A8V0ZS27-1", "A0A8V1A9M0-1", "E1BZ35-1", "E1C3Q9-1", "F1NC08-1", "F1P2G0-1", "A0A8V0YYC5-1", "A0A8V0Z4C8-1", "A0A8V0Z596-1", "A0A1D5P284-1", "A0A8V0ZF21-1", "A0A3Q2U2G8-1", "A0A8V1A1N8-1", "A0A8V1A233-1", "A0A8V1A7P9-1", "A0A8V0ZSA3-1", "E1C656-1", "A0A8V0Y0Q7-1", "A0A8V0Y5C7-1", "A0A8V0YCS7-1", "A0A8V0YDQ1-1", "A0A8V0YGF4-1", "A0A8V0YJK8-1", "A0A8V0YLY7-1", "A0A8V0ZKK3-1", "A0A8V0ZKQ3-1" ], "evidence": [ { "id": "R-GGA-983147", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983147" } ] }, { "id": "R-GGA-983156", "name": "Polyubiquitination of substrate", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0X324-1", "A0A8V0XEM6-1", "A0A8V0XJC4-1", "A0A8V0XQR1-1", "A0A8V1AC19-1", "A0A8V1AC55-1", "A0A8V1AKB8-1", "A0A8V1ALH0-1", "F1NL19-1", "F1NRC6-1", "F1NTZ8-1", "A0A8V0YHL7-1", "A0A8V0YPW4-1", "A0A8V0YRM6-1", "A0A8V0YV22-1", "A0A8V0YVP3-1", "A0A8V0Z2L5-1", "F1NL77-1", "E1C982-1", "A0A3Q2UC96-1", "Q5ZKX6-1", "Z4YJC3-1", "A0A8V0XQU7-1", "A0A8V0Y5C9-1", "A0A8V1AL09-1", "A0A8V1AML5-1", "A0A8V1AP69-1", "F1NVY8-1", "R4GIV8-1", "A0A8V0ZJ49-1", "A0A8V0ZJV9-1", "A0A8V0ZL18-1", "A0A8V0ZM17-1", "A0A8V0ZSH4-1", "A0A8V0ZVX3-1", "A0A8V0ZW26-1", "A0A8V1A0Z6-1", "A0A8V0ZZH3-1", "A0A8V1A052-1", "A0A8V1A0X2-1", "A0A8V1A1I4-1", "A0A8V1A2W7-1", "A0A8V1A5P4-1", "A0A8V1A7T1-1", "A0A8V0XTY5-1", "A0A8V0Y5B5-1", "A0A8V0YL05-1", "A0A8V0Z082-1", "A0A8V0ZS27-1", "A0A8V1A9M0-1", "E1BZ35-1", "E1C3Q9-1", "F1NC08-1", "F1P2G0-1", "A0A8V0YY10-1", "A0A8V0YYC5-1", "A0A8V0Z1W7-1", "A0A8V0Z4C8-1", "A0A8V0Z596-1", "A0A1D5P284-1", "A0A8V0ZF21-1", "A0A3Q2U2G8-1", "A0A8V1A4H7-1", "A0A8V1A1N8-1", "A0A8V1A233-1", "A0A8V1A7P9-1", "A0A8V1ACU3-1", "A0A8V0ZSA3-1", "E1C656-1", "A0A8V0Y0Q7-1", "A0A8V0Y059-1", "A0A8V0Y5C7-1", "A0A8V0YCS7-1", "A0A8V0YDQ1-1", "A0A8V0YFD9-1", "A0A8V0YGF4-1", "A0A8V0YJK8-1", "A0A8V0YLY7-1", "A0A1D5NVE2-1", "A0A8V0ZKK3-1", "A0A8V0ZKQ3-1" ], "evidence": [ { "id": "R-GGA-983156", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983156" } ] }, { "id": "R-GGA-983157", "name": "Interaction of E3 with substrate and E2-Ub complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0X324-1", "A0A8V0XEM6-1", "A0A8V0XJC4-1", "A0A8V0XQR1-1", "A0A8V1AC19-1", "A0A8V1AC55-1", "A0A8V1AKB8-1", "A0A8V1ALH0-1", "F1NL19-1", "F1NRC6-1", "F1NTZ8-1", "A0A8V0YHL7-1", "A0A8V0YPW4-1", "A0A8V0YRM6-1", "A0A8V0YV22-1", "A0A8V0YVP3-1", "A0A8V0Z2L5-1", "F1NL77-1", "E1C982-1", "A0A3Q2UC96-1", "Q5ZKX6-1", "Z4YJC3-1", "A0A8V0XQU7-1", "A0A8V0Y5C9-1", "A0A8V1AL09-1", "A0A8V1AML5-1", "A0A8V1AP69-1", "F1NVY8-1", "R4GIV8-1", "A0A8V0ZJ49-1", "A0A8V0ZJV9-1", "A0A8V0ZL18-1", "A0A8V0ZM17-1", "A0A8V0ZSH4-1", "A0A8V0ZVX3-1", "A0A8V0ZW26-1", "A0A8V1A0Z6-1", "A0A8V0ZZH3-1", "A0A8V1A052-1", "A0A8V1A0X2-1", "A0A8V1A1I4-1", "A0A8V1A2W7-1", "A0A8V1A5P4-1", "A0A8V1A7T1-1", "A0A8V0XTY5-1", "A0A8V0Y5B5-1", "A0A8V0YL05-1", "A0A8V0Z082-1", "A0A8V0ZS27-1", "A0A8V1A9M0-1", "E1BZ35-1", "E1C3Q9-1", "F1NC08-1", "F1P2G0-1", "A0A8V0YY10-1", "A0A8V0YYC5-1", "A0A8V0Z1W7-1", "A0A8V0Z4C8-1", "A0A8V0Z596-1", "A0A1D5P284-1", "A0A8V0ZF21-1", "A0A3Q2U2G8-1", "A0A8V1A4H7-1", "A0A8V1A1N8-1", "A0A8V1A233-1", "A0A8V1A7P9-1", "A0A8V1ACU3-1", "A0A8V0ZSA3-1", "E1C656-1", "A0A8V0Y0Q7-1", "A0A8V0Y059-1", "A0A8V0Y5C7-1", "A0A8V0YCS7-1", "A0A8V0YDQ1-1", "A0A8V0YFD9-1", "A0A8V0YGF4-1", "A0A8V0YJK8-1", "A0A8V0YLY7-1", "A0A1D5NVE2-1", "A0A8V0ZKK3-1", "A0A8V0ZKQ3-1" ], "evidence": [ { "id": "R-GGA-983157", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983157" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5NVE2", "gene_name": "UBE2Q1", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A1D5NVE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVE2" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A1D5NVE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVE2" } ] } ] }, { "uniprot_ac": "A0A1D5NWT4", "gene_name": "RPS6KA3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5NWT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NWT4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5NWT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NWT4" } ] } ] }, { "uniprot_ac": "A0A1D5P0M9", "gene_name": "MAP3K13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5P0M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P0M9" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A1D5P0M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P0M9" } ] } ] }, { "uniprot_ac": "A0A1D5P284", "gene_name": "UBR2", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A1D5P284", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P284" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A1D5P284", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P284" } ] } ] }, { "uniprot_ac": "A0A1D5P517", "gene_name": "PLK3", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5P517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P517" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A1D5P517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P517" } ] } ] }, { "uniprot_ac": "A0A1D5P8A9", "gene_name": "SNRK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5P8A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P8A9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5P8A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P8A9" } ] } ] }, { "uniprot_ac": "A0A1D5PA08", "gene_name": "STK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PA08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PA08" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5PA08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PA08" } ] } ] }, { "uniprot_ac": "A0A1D5PB73", "gene_name": "CASK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PB73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PB73" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5PB73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PB73" } ] } ] }, { "uniprot_ac": "A0A1D5PD64", "gene_name": "MAP2K3", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PD64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PD64" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A1D5PD64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PD64" } ] } ] }, { "uniprot_ac": "A0A1D5PMG2", "gene_name": "DCLK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PMG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMG2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5PMG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMG2" } ] } ] }, { "uniprot_ac": "A0A1D5PMQ7", "gene_name": "STK40", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PMQ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMQ7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5PMQ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMQ7" } ] } ] }, { "uniprot_ac": "A0A1D5PRN8", "gene_name": "DAPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PRN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRN8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5PRN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRN8" } ] } ] }, { "uniprot_ac": "A0A1D5PTJ8", "gene_name": "MAP3K5", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PTJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PTJ8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A1D5PTJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PTJ8" } ] } ] }, { "uniprot_ac": "A0A1D5PUY5", "gene_name": "PRKCB", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PUY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUY5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A1D5PUY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUY5" } ] } ] }, { "uniprot_ac": "A0A1D5PV76", "gene_name": "STK17A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PV76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PV76" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5PV76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PV76" } ] } ] }, { "uniprot_ac": "A0A1D5PX90", "gene_name": "KSR2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PX90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PX90" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5PX90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PX90" } ] } ] }, { "uniprot_ac": "A0A1D5PXN4", "gene_name": "PRKCD", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PXN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PXN4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A1D5PXN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PXN4" } ] } ] }, { "uniprot_ac": "A0A1L1RWI9", "gene_name": "CAMK4", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1L1RWI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RWI9" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A1L1RWI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RWI9" } ] } ] }, { "uniprot_ac": "A0A3Q2TRY2", "gene_name": "TAOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2TRY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TRY2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q2TRY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TRY2" } ] } ] }, { "uniprot_ac": "A0A3Q2TUS7", "gene_name": "TLK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2TUS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TUS7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q2TUS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TUS7" } ] } ] }, { "uniprot_ac": "A0A3Q2TV19", "gene_name": "UHMK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2TV19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TV19" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q2TV19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TV19" } ] } ] }, { "uniprot_ac": "A0A3Q2TWZ8", "gene_name": "MAP3K20", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2TWZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TWZ8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A3Q2TWZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TWZ8" } ] } ] }, { "uniprot_ac": "A0A3Q2TY19", "gene_name": "MAPK8", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2TY19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TY19" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A3Q2TY19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TY19" } ] } ] }, { "uniprot_ac": "A0A3Q2U2G8", "gene_name": "TRIM9", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A3Q2U2G8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U2G8" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A3Q2U2G8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U2G8" } ] } ] }, { "uniprot_ac": "A0A3Q2U4X3", "gene_name": "AKT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2U4X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U4X3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q2U4X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U4X3" } ] } ] }, { "uniprot_ac": "A0A3Q2U592", "gene_name": "DCLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2U592", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U592" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q2U592", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U592" } ] } ] }, { "uniprot_ac": "A0A3Q2U9U9", "gene_name": "OXSR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2U9U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U9U9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q2U9U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U9U9" } ] } ] }, { "uniprot_ac": "A0A3Q2UC96", "gene_name": "NEDD4L", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A3Q2UC96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UC96" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A3Q2UC96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UC96" } ] } ] }, { "uniprot_ac": "A0A3Q2UF44", "gene_name": "NEK8", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2UF44", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UF44" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q2UF44", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UF44" } ] } ] }, { "uniprot_ac": "A0A3Q2UI52", "gene_name": "LATS2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2UI52", "database": "UniProtKB", "url": 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"ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A3Q3A664", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3A664" } ] } ] }, { "uniprot_ac": "A0A3Q3AAD7", "gene_name": "STK35", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q3AAD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3AAD7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q3AAD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3AAD7" } ] } ] }, { "uniprot_ac": "A0A3Q3B2F1", "gene_name": "PKN3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q3B2F1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3B2F1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A3Q3B2F1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3B2F1" } ] } ] }, { "uniprot_ac": "A0A8V0X1Q7", "gene_name": "MELK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X1Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X1Q7" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X1Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X1Q7" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0X1Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X1Q7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0X1Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X1Q7" } ] } ] }, { "uniprot_ac": "A0A8V0X2Y2", "gene_name": "MAPK12", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X2Y2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X2Y2" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0X2Y2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X2Y2" } ] } ] }, { "uniprot_ac": "A0A8V0X324", "gene_name": "UBE2E1", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0X324", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X324" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0X324", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X324" } ] } ] }, { "uniprot_ac": "A0A8V0X3D6", "gene_name": "LOC100858386", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X3D6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X3D6" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0X3D6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X3D6" } ] } ] }, { "uniprot_ac": "A0A8V0X4P0", "gene_name": "CDKL5", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X4P0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X4P0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0X4P0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X4P0" } ] } ] }, { "uniprot_ac": "A0A8V0X4Q3", "gene_name": "ICK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X4Q3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X4Q3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0X4Q3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X4Q3" } ] } ] }, { "uniprot_ac": "A0A8V0X5Z8", "gene_name": "NEK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X5Z8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X5Z8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0X5Z8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X5Z8" } ] } ] }, { "uniprot_ac": "A0A8V0X6T4", "gene_name": "LOC107050692", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X6T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X6T4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0X6T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X6T4" } ] } ] }, { "uniprot_ac": "A0A8V0X7R2", "gene_name": "SBK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X7R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X7R2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0X7R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X7R2" } ] } ] }, { "uniprot_ac": "A0A8V0X8M1", "gene_name": "TRIO", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X8M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X8M1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0X8M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X8M1" } ] } ] }, { "uniprot_ac": "A0A8V0XAH9", "gene_name": "NEK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XAH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XAH9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XAH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XAH9" } ] } ] }, { "uniprot_ac": "A0A8V0XB58", "gene_name": "CAMK2D", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XB58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XB58" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V0XB58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XB58" } ] } ] }, { "uniprot_ac": "A0A8V0XBZ0", "gene_name": "STK32C", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XBZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XBZ0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XBZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XBZ0" } ] } ] }, { "uniprot_ac": "A0A8V0XCS0", "gene_name": "PRKG2", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XCS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCS0" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0A8V0XCS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCS0" } ] } ] }, { "uniprot_ac": "A0A8V0XCV5", "gene_name": "MAP3K7", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XCV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCV5" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0XCV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCV5" } ] } ] }, { "uniprot_ac": "A0A8V0XCY6", "gene_name": "TTK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XCY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCY6" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V0XCY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCY6" } ] } ] }, { "uniprot_ac": "A0A8V0XDR5", "gene_name": "IRAK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XDR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XDR5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XDR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XDR5" } ] } ] }, { "uniprot_ac": "A0A8V0XE48", "gene_name": "ROCK2", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XE48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XE48" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "A0A8V0XE48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XE48" } ] } ] }, { "uniprot_ac": "A0A8V0XEA3", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XEA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEA3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XEA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEA3" } ] } ] }, { "uniprot_ac": "A0A8V0XEM6", "gene_name": "HERC2", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0XEM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEM6" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0XEM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEM6" } ] } ] }, { "uniprot_ac": "A0A8V0XFW1", "gene_name": "SGK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XFW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFW1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XFW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFW1" } ] } ] }, { "uniprot_ac": "A0A8V0XFX2", "gene_name": "NEK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XFX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFX2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XFX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFX2" } ] } ] }, { "uniprot_ac": "A0A8V0XG21", "gene_name": "LOC107050335", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XG21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XG21" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XG21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XG21" } ] } ] }, { "uniprot_ac": "A0A8V0XI18", "gene_name": "ATM", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XI18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XI18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XI18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XI18" } ] } ] }, { "uniprot_ac": "A0A8V0XJC4", "gene_name": "UBE3D", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0XJC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJC4" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0XJC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJC4" } ] } ] }, { "uniprot_ac": "A0A8V0XKG0", "gene_name": "NEK9", "activity": [ { "ec_number": "2.7.11.38", "activity": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XKG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XKG0" } ] }, { "ec_number": "2.7.11.38", "activity": "", "evidence": [ { "id": "A0A8V0XKG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XKG0" } ] } ] }, { "uniprot_ac": "A0A8V0XLV6", "gene_name": "MAPK10", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XLV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLV6" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0XLV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLV6" } ] } ] }, { "uniprot_ac": "A0A8V0XMT1", "gene_name": "MOS", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XMT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMT1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XMT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMT1" } ] } ] }, { "uniprot_ac": "A0A8V0XMX8", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMX8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMX8" } ] } ] }, { "uniprot_ac": "A0A8V0XND6", "gene_name": "RIOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XND6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XND6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XND6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XND6" } ] } ] }, { "uniprot_ac": "A0A8V0XNJ2", "gene_name": "CDK8", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] } ] }, { "uniprot_ac": "A0A8V0XNK8", "gene_name": "PRKCQ", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XNK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNK8" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0XNK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNK8" } ] } ] }, { "uniprot_ac": "A0A8V0XQ14", "gene_name": "PLK4", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQ14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ14" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A8V0XQ14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ14" } ] } ] }, { "uniprot_ac": "A0A8V0XQ97", "gene_name": "CDK14", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQ97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ97" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0XQ97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ97" } ] } ] }, { "uniprot_ac": "A0A8V0XQQ4", "gene_name": "NME7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQQ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQQ4" } ] } ] }, { "uniprot_ac": "A0A8V0XQR1", "gene_name": "UBE2H", "activity": [ { "ec_number": "2.3.2.24", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E1 ubiquitin-activating enzyme]-L-cysteine + N(6)-monoubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0XQR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQR1" } ] }, { "ec_number": "2.3.2.24", "activity": "", "evidence": [ { "id": "A0A8V0XQR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQR1" } ] } ] }, { "uniprot_ac": "A0A8V0XQS0", "gene_name": "STK24", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQS0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XQS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQS0" } ] } ] }, { "uniprot_ac": "A0A8V0XQU7", "gene_name": "RNF6", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0XQU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQU7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0XQU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQU7" } ] } ] }, { "uniprot_ac": "A0A8V0XS42", "gene_name": "MAP3K4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XS42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XS42" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0XS42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XS42" } ] } ] }, { "uniprot_ac": "A0A8V0XTY5", "gene_name": "SH3RF1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0XTY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XTY5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0XTY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XTY5" } ] } ] }, { "uniprot_ac": "A0A8V0XU71", "gene_name": "MYO3A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XU71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU71" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XU71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU71" } ] } ] }, { "uniprot_ac": "A0A8V0XU96", "gene_name": "PRKD1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XU96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU96" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0XU96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU96" } ] } ] }, { "uniprot_ac": "A0A8V0XUM6", "gene_name": "LATS1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XUM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XUM6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XUM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XUM6" } ] } ] }, { "uniprot_ac": "A0A8V0XW11", "gene_name": "RPS6KA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XW11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW11" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XW11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW11" } ] } ] }, { "uniprot_ac": "A0A8V0XW29", "gene_name": "CDKL2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XW29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW29" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0XW29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW29" } ] } ] }, { "uniprot_ac": "A0A8V0XXB8", "gene_name": "MAPK15", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XXB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXB8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0XXB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXB8" } ] } ] }, { "uniprot_ac": "A0A8V0Y059", "gene_name": "UBE2D1", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0Y059", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y059" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0Y059", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y059" } ] } ] }, { "uniprot_ac": "A0A8V0Y074", "gene_name": "NEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y074", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y074" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y074", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y074" } ] } ] }, { "uniprot_ac": "A0A8V0Y0Q7", "gene_name": "RNF144B", "activity": [ { "ec_number": "2.3.2.31", "activity": "[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.", "evidence": [ { "id": "A0A8V0Y0Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y0Q7" } ] }, { "ec_number": "2.3.2.31", "activity": "", "evidence": [ { "id": "A0A8V0Y0Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y0Q7" } ] } ] }, { "uniprot_ac": "A0A8V0Y241", "gene_name": "LOC426385", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y241", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y241" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y241", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y241" } ] } ] }, { "uniprot_ac": "A0A8V0Y2I5", "gene_name": "CDK7", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] } ] }, { "uniprot_ac": "A0A8V0Y3D1", "gene_name": "LRRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y3D1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3D1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y3D1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3D1" } ] } ] }, { "uniprot_ac": "A0A8V0Y3L2", "gene_name": "MLK4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y3L2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3L2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0Y3L2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3L2" } ] } ] }, { "uniprot_ac": "A0A8V0Y457", "gene_name": "PRPF4B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y457", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y457" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y457", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y457" } ] } ] }, { "uniprot_ac": "A0A8V0Y4L8", "gene_name": "HUNK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y4L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y4L8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y4L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y4L8" } ] } ] }, { "uniprot_ac": "A0A8V0Y5B5", "gene_name": "LTN1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Y5B5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5B5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0Y5B5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5B5" } ] } ] }, { "uniprot_ac": "A0A8V0Y5C7", "gene_name": "CBLL1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Y5C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5C7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0Y5C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5C7" } ] } ] }, { "uniprot_ac": "A0A8V0Y5C9", "gene_name": "HERC3", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Y5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5C9" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0Y5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5C9" } ] } ] }, { "uniprot_ac": "A0A8V0Y6K1", "gene_name": "MAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6K1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6K1" } ] } ] }, { "uniprot_ac": "A0A8V0Y7C3", "gene_name": "DAPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y7C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7C3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y7C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7C3" } ] } ] }, { "uniprot_ac": "A0A8V0Y823", "gene_name": "SRPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y823", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y823" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y823", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y823" } ] } ] }, { "uniprot_ac": "A0A8V0Y8X9", "gene_name": "PRKACA", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y8X9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8X9" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0A8V0Y8X9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8X9" } ] } ] }, { "uniprot_ac": "A0A8V0Y935", "gene_name": "MAST4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y935", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y935" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y935", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y935" } ] } ] }, { "uniprot_ac": "A0A8V0Y955", "gene_name": "PAK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y955", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y955" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y955", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y955" } ] } ] }, { "uniprot_ac": "A0A8V0Y9Q1", "gene_name": "LOC107055388", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y9Q1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9Q1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y9Q1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9Q1" } ] } ] }, { "uniprot_ac": "A0A8V0YCS7", "gene_name": "RNF19A", "activity": [ { "ec_number": "2.3.2.31", "activity": "[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.", "evidence": [ { "id": "A0A8V0YCS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCS7" } ] }, { "ec_number": "2.3.2.31", "activity": "", "evidence": [ { "id": "A0A8V0YCS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCS7" } ] } ] }, { "uniprot_ac": "A0A8V0YCV9", "gene_name": "SIK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YCV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YCV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCV9" } ] } ] }, { "uniprot_ac": "A0A8V0YCY4", "gene_name": "AURKB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YCY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YCY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY4" } ] } ] }, { "uniprot_ac": "A0A8V0YCY8", "gene_name": "RIOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YCY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YCY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY8" } ] } ] }, { "uniprot_ac": "A0A8V0YDH4", "gene_name": "ALPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YDH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDH4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YDH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDH4" } ] } ] }, { "uniprot_ac": "A0A8V0YDQ1", "gene_name": "WWP1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YDQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDQ1" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0YDQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDQ1" } ] } ] }, { "uniprot_ac": "A0A8V0YF83", "gene_name": "WNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YF83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF83" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YF83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF83" } ] } ] }, { "uniprot_ac": "A0A8V0YFD9", "gene_name": "UBE2D2", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0YFD9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFD9" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0YFD9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFD9" } ] } ] }, { "uniprot_ac": "A0A8V0YFH4", "gene_name": "NRK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFH4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YFH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFH4" } ] } ] }, { "uniprot_ac": "A0A8V0YFL1", "gene_name": "CDK19", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0YFL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL1" } ] } ] }, { "uniprot_ac": "A0A8V0YFP8", "gene_name": "RIPK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFP8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YFP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFP8" } ] } ] }, { "uniprot_ac": "A0A8V0YFR6", "gene_name": "TNIK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFR6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YFR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFR6" } ] } ] }, { "uniprot_ac": "A0A8V0YGF4", "gene_name": "MYLIP", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YGF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGF4" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YGF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGF4" } ] } ] }, { "uniprot_ac": "A0A8V0YGW2", "gene_name": "STK32B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YGW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGW2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YGW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGW2" } ] } ] }, { "uniprot_ac": "A0A8V0YHH2", "gene_name": "STK38L", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YHH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHH2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YHH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHH2" } ] } ] }, { "uniprot_ac": "A0A8V0YHL7", "gene_name": "RNF114", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YHL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHL7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YHL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHL7" } ] } ] }, { "uniprot_ac": "A0A8V0YHN2", "gene_name": "RPS6KA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YHN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YHN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN2" } ] } ] }, { "uniprot_ac": "A0A8V0YIV6", "gene_name": "DYRK1A", "activity": [ { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] } ] }, { "uniprot_ac": "A0A8V0YJK8", "gene_name": "RNF14", "activity": [ { "ec_number": "2.3.2.31", "activity": "[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.", "evidence": [ { "id": "A0A8V0YJK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJK8" } ] }, { "ec_number": "2.3.2.31", "activity": "", "evidence": [ { "id": "A0A8V0YJK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJK8" } ] } ] }, { "uniprot_ac": "A0A8V0YJP9", "gene_name": "RIOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YJP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YJP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP9" } ] } ] }, { "uniprot_ac": "A0A8V0YK18", "gene_name": "CDC42BPB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YK18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YK18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK18" } ] } ] }, { "uniprot_ac": "A0A8V0YKK3", "gene_name": "MAP4K4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKK3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKK3" } ] } ] }, { "uniprot_ac": "A0A8V0YL05", "gene_name": "UBE3A", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YL05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL05" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0YL05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL05" } ] } ] }, { "uniprot_ac": "A0A8V0YLV1", "gene_name": "MARK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YLV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLV1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YLV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLV1" } ] } ] }, { "uniprot_ac": "A0A8V0YLY7", "gene_name": "MKRN4P", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLY7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLY7" } ] } ] }, { "uniprot_ac": "A0A8V0YM22", "gene_name": "MYO3AL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YM22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM22" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YM22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM22" } ] } ] }, { "uniprot_ac": "A0A8V0YM96", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YM96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM96" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YM96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM96" } ] } ] }, { "uniprot_ac": "A0A8V0YMB3", "gene_name": "STK32A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMB3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMB3" } ] } ] }, { "uniprot_ac": "A0A8V0YMN5", "gene_name": "BRAF", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YMN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YMN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN5" } ] } ] }, { "uniprot_ac": "A0A8V0YNI5", "gene_name": "NIM1K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YNI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNI5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YNI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNI5" } ] } ] }, { "uniprot_ac": "A0A8V0YPW4", "gene_name": "UBE2J2", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0YPW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPW4" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0YPW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPW4" } ] } ] }, { "uniprot_ac": "A0A8V0YRC9", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] } ] }, { "uniprot_ac": "A0A8V0YRM6", "gene_name": "RNF130", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YRM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRM6" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YRM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRM6" } ] } ] }, { "uniprot_ac": "A0A8V0YRN4", "gene_name": "GAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRN4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YRN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRN4" } ] } ] }, { "uniprot_ac": "A0A8V0YSH3", "gene_name": "RPS6KA6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YSH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSH3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YSH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSH3" } ] } ] }, { "uniprot_ac": "A0A8V0YTI1", "gene_name": "TSSK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTI1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTI1" } ] } ] }, { "uniprot_ac": "A0A8V0YTL9", "gene_name": "VRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTL9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTL9" } ] } ] }, { "uniprot_ac": "A0A8V0YTN5", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTN5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTN5" } ] } ] }, { "uniprot_ac": "A0A8V0YTP2", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTP2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTP2" } ] } ] }, { "uniprot_ac": "A0A8V0YV22", "gene_name": "RNF4", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YV22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YV22" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YV22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YV22" } ] } ] }, { "uniprot_ac": "A0A8V0YVP3", "gene_name": "RBBP6", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YVP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVP3" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YVP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVP3" } ] } ] }, { "uniprot_ac": "A0A8V0YXZ5", "gene_name": "CDC42BPA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YXZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXZ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YXZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXZ5" } ] } ] }, { "uniprot_ac": "A0A8V0YY10", "gene_name": "UBE2D3", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0YY10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YY10" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0YY10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YY10" } ] } ] }, { "uniprot_ac": "A0A8V0YYC5", "gene_name": "ZNRF2", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YYC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYC5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YYC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYC5" } ] } ] }, { "uniprot_ac": "A0A8V0YYX2", "gene_name": "PAK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YYX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYX2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YYX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYX2" } ] } ] }, { "uniprot_ac": "A0A8V0YYZ3", "gene_name": "SPEG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YYZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYZ3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YYZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYZ3" } ] } ] }, { "uniprot_ac": "A0A8V0YZ74", "gene_name": "MAP2K5", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZ74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZ74" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V0YZ74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZ74" } ] } ] }, { "uniprot_ac": "A0A8V0YZF2", "gene_name": "PAK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZF2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YZF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZF2" } ] } ] }, { "uniprot_ac": "A0A8V0YZK0", "gene_name": "MAP3K6", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZK0" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0YZK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZK0" } ] } ] }, { "uniprot_ac": "A0A8V0YZM1", "gene_name": "MOK", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] }, { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] } ] }, { "uniprot_ac": "A0A8V0YZV9", "gene_name": "ATR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YZV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZV9" } ] } ] }, { "uniprot_ac": "A0A8V0YZY4", "gene_name": "SBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZY4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YZY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZY4" } ] } ] }, { "uniprot_ac": "A0A8V0Z082", "gene_name": "UBE2B", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0Z082", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z082" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0Z082", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z082" } ] } ] }, { "uniprot_ac": "A0A8V0Z124", "gene_name": "VRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z124", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z124" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z124", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z124" } ] } ] }, { "uniprot_ac": "A0A8V0Z157", "gene_name": "MARK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] } ] }, { "uniprot_ac": "A0A8V0Z1W7", "gene_name": "UBE2K", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0Z1W7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1W7" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0Z1W7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1W7" } ] } ] }, { "uniprot_ac": "A0A8V0Z1X0", "gene_name": "MAP4K3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z1X0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1X0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z1X0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1X0" } ] } ] }, { "uniprot_ac": "A0A8V0Z283", "gene_name": "MARK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] } ] }, { "uniprot_ac": "A0A8V0Z2E3", "gene_name": "PDIK1L", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z2E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2E3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z2E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2E3" } ] } ] }, { "uniprot_ac": "A0A8V0Z2L5", "gene_name": "TRIM63", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Z2L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2L5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0Z2L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2L5" } ] } ] }, { "uniprot_ac": "A0A8V0Z2Z3", "gene_name": "AAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z2Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2Z3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z2Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2Z3" } ] } ] }, { "uniprot_ac": "A0A8V0Z466", "gene_name": "MAP3K19", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z466", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z466" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z466", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z466" } ] } ] }, { "uniprot_ac": "A0A8V0Z4C8", "gene_name": "MGRN1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Z4C8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4C8" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0Z4C8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4C8" } ] } ] }, { "uniprot_ac": "A0A8V0Z596", "gene_name": "STUB1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Z596", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z596" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0Z596", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z596" } ] } ] }, { "uniprot_ac": "A0A8V0Z6K4", "gene_name": "PIK3R4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z6K4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6K4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z6K4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6K4" } ] } ] }, { "uniprot_ac": "A0A8V0Z6T1", "gene_name": "ERN2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z6T1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6T1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z6T1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6T1" } ] } ] }, { "uniprot_ac": "A0A8V0Z807", "gene_name": "NEK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z807", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z807" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z807", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z807" } ] } ] }, { "uniprot_ac": "A0A8V0Z8G2", "gene_name": "TTBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z8G2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8G2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z8G2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8G2" } ] } ] }, { "uniprot_ac": "A0A8V0Z8T4", "gene_name": "RPS6KC1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z8T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8T4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z8T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8T4" } ] } ] }, { "uniprot_ac": "A0A8V0Z927", "gene_name": "PINK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z927", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z927" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z927", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z927" } ] } ] }, { "uniprot_ac": "A0A8V0Z930", "gene_name": "CAMK2B", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z930", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z930" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V0Z930", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z930" } ] } ] }, { "uniprot_ac": "A0A8V0Z9J0", "gene_name": "CIT", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z9J0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9J0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z9J0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9J0" } ] } ] }, { "uniprot_ac": "A0A8V0ZA06", "gene_name": "CDKL1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA06" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0ZA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA06" } ] } ] }, { "uniprot_ac": "A0A8V0ZA45", "gene_name": "MAP4K5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZA45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA45" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZA45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA45" } ] } ] }, { "uniprot_ac": "A0A8V0ZB33", "gene_name": "CAMK2G", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZB33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB33" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V0ZB33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB33" } ] } ] }, { "uniprot_ac": "A0A8V0ZB38", "gene_name": "CIITA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZB38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB38" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZB38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB38" } ] } ] }, { "uniprot_ac": "A0A8V0ZBN6", "gene_name": "MAP2K1", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZBN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBN6" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V0ZBN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBN6" } ] } ] }, { "uniprot_ac": "A0A8V0ZBZ2", "gene_name": "MAP3K9", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZBZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBZ2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0ZBZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBZ2" } ] } ] }, { "uniprot_ac": "A0A8V0ZC16", "gene_name": "KALRN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZC16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC16" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZC16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC16" } ] } ] }, { "uniprot_ac": "A0A8V0ZD40", "gene_name": "CDC2L1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] } ] }, { "uniprot_ac": "A0A8V0ZD48", "gene_name": "PRKCE", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD48" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0ZD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD48" } ] } ] }, { "uniprot_ac": "A0A8V0ZD60", "gene_name": "STK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZD60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD60" } ] } ] }, { "uniprot_ac": "A0A8V0ZD70", "gene_name": "DCLK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD70" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZD70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD70" } ] } ] }, { "uniprot_ac": "A0A8V0ZDW9", "gene_name": "NEK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZDW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDW9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZDW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDW9" } ] } ] }, { "uniprot_ac": "A0A8V0ZF21", "gene_name": "DTX3L", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZF21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF21" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZF21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF21" } ] } ] }, { "uniprot_ac": "A0A8V0ZFM2", "gene_name": "LMTK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZFM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFM2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZFM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFM2" } ] } ] }, { "uniprot_ac": "A0A8V0ZFP1", "gene_name": "TTBK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZFP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFP1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZFP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFP1" } ] } ] }, { "uniprot_ac": "A0A8V0ZFT3", "gene_name": "LRRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZFT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFT3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZFT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFT3" } ] } ] }, { "uniprot_ac": "A0A8V0ZGY3", "gene_name": "HIPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZGY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGY3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZGY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGY3" } ] } ] }, { "uniprot_ac": "A0A8V0ZH91", "gene_name": "WNK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZH91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH91" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZH91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH91" } ] } ] }, { "uniprot_ac": "A0A8V0ZI32", "gene_name": "STK16", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZI32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI32" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZI32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI32" } ] } ] }, { "uniprot_ac": "A0A8V0ZJ49", "gene_name": "SMURF1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZJ49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ49" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZJ49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ49" } ] } ] }, { "uniprot_ac": "A0A8V0ZJV9", "gene_name": "MIB2", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZJV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJV9" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZJV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJV9" } ] } ] }, { "uniprot_ac": "A0A8V0ZK64", "gene_name": "PDPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZK64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK64" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZK64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK64" } ] } ] }, { "uniprot_ac": "A0A8V0ZKA2", "gene_name": "EIF2AK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZKA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKA2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZKA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKA2" } ] } ] }, { "uniprot_ac": "A0A8V0ZKK3", "gene_name": "UBE3B", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKK3" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKK3" } ] } ] }, { "uniprot_ac": "A0A8V0ZKM9", "gene_name": "STK36", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZKM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKM9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZKM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKM9" } ] } ] }, { "uniprot_ac": "A0A8V0ZKQ3", "gene_name": "RNF25", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZKQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKQ3" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZKQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKQ3" } ] } ] }, { "uniprot_ac": "A0A8V0ZL18", "gene_name": "HECTD2", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZL18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL18" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZL18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL18" } ] } ] }, { "uniprot_ac": "A0A8V0ZLU3", "gene_name": "TLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZLU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLU3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZLU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLU3" } ] } ] }, { "uniprot_ac": "A0A8V0ZM17", "gene_name": "UBR1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZM17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM17" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZM17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM17" } ] } ] }, { "uniprot_ac": "A0A8V0ZMK1", "gene_name": "PIKFYVE", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] }, { "ec_number": "2.7.1.150", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] }, { "ec_number": "2.7.1.150", "activity": "", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] } ] }, { "uniprot_ac": "A0A8V0ZNP7", "gene_name": "SGK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZNP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNP7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZNP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNP7" } ] } ] }, { "uniprot_ac": "A0A8V0ZPX2", "gene_name": "ALPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZPX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPX2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZPX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPX2" } ] } ] }, { "uniprot_ac": "A0A8V0ZQJ2", "gene_name": "RPS6KB2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZQJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZQJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQJ2" } ] } ] }, { "uniprot_ac": "A0A8V0ZQT5", "gene_name": "SLC13A3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZQT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQT5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZQT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQT5" } ] } ] }, { "uniprot_ac": "A0A8V0ZRX1", "gene_name": "SETD6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZRX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRX1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZRX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRX1" } ] }, { "ec_number": "2.1.1.-", "activity": "", "evidence": [ { "id": "A0A8V0ZRX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRX1" } ] } ] }, { "uniprot_ac": "A0A8V0ZS27", "gene_name": "TRIP12", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZS27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS27" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZS27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS27" } ] } ] }, { "uniprot_ac": "A0A8V0ZSA3", "gene_name": "HERC4", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZSA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSA3" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZSA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSA3" } ] } ] }, { "uniprot_ac": "A0A8V0ZSB4", "gene_name": "SIK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZSB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSB4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZSB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSB4" } ] } ] }, { "uniprot_ac": "A0A8V0ZSH4", "gene_name": "RNF111", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZSH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSH4" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZSH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSH4" } ] } ] }, { "uniprot_ac": "A0A8V0ZSP4", "gene_name": "PKN2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] }, { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] } ] }, { "uniprot_ac": "A0A8V0ZT63", "gene_name": "STK25", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZT63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT63" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZT63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT63" } ] } ] }, { "uniprot_ac": "A0A8V0ZUC6", "gene_name": "PAK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUC6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUC6" } ] } ] }, { "uniprot_ac": "A0A8V0ZUL0", "gene_name": "PASK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUL0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUL0" } ] } ] }, { "uniprot_ac": "A0A8V0ZUU8", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU8" } ] } ] }, { "uniprot_ac": "A0A8V0ZUU9", "gene_name": "MKNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU9" } ] } ] }, { "uniprot_ac": "A0A8V0ZVX3", "gene_name": "NEDD4", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZVX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVX3" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZVX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVX3" } ] } ] }, { "uniprot_ac": "A0A8V0ZW26", "gene_name": "ZNRF1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZW26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZW26" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZW26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZW26" } ] } ] }, { "uniprot_ac": "A0A8V0ZWC7", "gene_name": "EIF2AK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZWC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWC7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZWC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWC7" } ] } ] }, { "uniprot_ac": "A0A8V0ZWW1", "gene_name": "MAP3K12", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZWW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWW1" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0ZWW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWW1" } ] } ] }, { "uniprot_ac": "A0A8V0ZXQ9", "gene_name": "PRKG1", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZXQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXQ9" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0A8V0ZXQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXQ9" } ] } ] }, { "uniprot_ac": "A0A8V0ZYU6", "gene_name": "TNNI3K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZYU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYU6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZYU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYU6" } ] } ] }, { "uniprot_ac": "A0A8V0ZZE4", "gene_name": "OBSCN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZZE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZE4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZZE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZE4" } ] } ] }, { "uniprot_ac": "A0A8V0ZZH3", "gene_name": "ITCH", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZZH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZH3" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZZH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZH3" } ] } ] }, { "uniprot_ac": "A0A8V0ZZK5", "gene_name": "STK38", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZZK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZK5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZZK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZK5" } ] } ] }, { "uniprot_ac": "A0A8V0ZZV3", "gene_name": "MYO3B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZZV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZV3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZZV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZV3" } ] } ] }, { "uniprot_ac": "A0A8V1A052", "gene_name": "UBE2E3", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V1A052", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A052" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V1A052", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A052" } ] } ] }, { "uniprot_ac": "A0A8V1A069", "gene_name": "TESK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A069", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A069" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1A069", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A069" } ] } ] }, { "uniprot_ac": "A0A8V1A0W4", "gene_name": "ULK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A0W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0W4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A0W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0W4" } ] } ] }, { "uniprot_ac": "A0A8V1A0X2", "gene_name": "UBE3C", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A0X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0X2" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V1A0X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0X2" } ] } ] }, { "uniprot_ac": "A0A8V1A0Y8", "gene_name": "MAST2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A0Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Y8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A0Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Y8" } ] } ] }, { "uniprot_ac": "A0A8V1A0Z6", "gene_name": "UBE4A", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A0Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Z6" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1A0Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Z6" } ] } ] }, { "uniprot_ac": "A0A8V1A1I4", "gene_name": "UBE2Z", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V1A1I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1I4" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V1A1I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1I4" } ] } ] }, { "uniprot_ac": "A0A8V1A1N8", "gene_name": "HERC1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A1N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1N8" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V1A1N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1N8" } ] } ] }, { "uniprot_ac": "A0A8V1A1P3", "gene_name": "SRPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A1P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1P3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A1P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1P3" } ] } ] }, { "uniprot_ac": "A0A8V1A1Y7", "gene_name": "CDK2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A1Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1Y7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V1A1Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1Y7" } ] } ] }, { "uniprot_ac": "A0A8V1A233", "gene_name": "RNF220", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A233", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A233" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1A233", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A233" } ] } ] }, { "uniprot_ac": "A0A8V1A2T9", "gene_name": "MAP3K14", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A2T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2T9" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V1A2T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2T9" } ] } ] }, { "uniprot_ac": "A0A8V1A2W7", "gene_name": "RNF41", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A2W7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2W7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1A2W7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2W7" } ] } ] }, { "uniprot_ac": "A0A8V1A3T8", "gene_name": "MAST3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A3T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3T8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A3T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3T8" } ] } ] }, { "uniprot_ac": "A0A8V1A4A1", "gene_name": "CAMKK2", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4A1" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1A4A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4A1" } ] } ] }, { "uniprot_ac": "A0A8V1A4H7", "gene_name": "UBE2L3", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V1A4H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4H7" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V1A4H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4H7" } ] } ] }, { "uniprot_ac": "A0A8V1A4J8", "gene_name": "MAPKAPK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4J8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A4J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4J8" } ] } ] }, { "uniprot_ac": "A0A8V1A4Q4", "gene_name": "MAPK3", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Q4" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1A4Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Q4" } ] } ] }, { "uniprot_ac": "A0A8V1A4V7", "gene_name": "HIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A4V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V7" } ] } ] }, { "uniprot_ac": "A0A8V1A513", "gene_name": "DAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A513" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A513" } ] } ] }, { "uniprot_ac": "A0A8V1A5P4", "gene_name": "UBE2G2", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V1A5P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5P4" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V1A5P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5P4" } ] } ] }, { "uniprot_ac": "A0A8V1A675", "gene_name": "CSNK1G2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A675", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A675" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A675", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A675" } ] } ] }, { "uniprot_ac": "A0A8V1A7E0", "gene_name": "DYRK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1A7E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E0" } ] } ] }, { "uniprot_ac": "A0A8V1A7E9", "gene_name": "SIK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E9" } ] } ] }, { "uniprot_ac": "A0A8V1A7M0", "gene_name": "STK39", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M0" } ] } ] }, { "uniprot_ac": "A0A8V1A7P9", "gene_name": "DCAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] } ] }, { "uniprot_ac": "A0A8V1A7T1", "gene_name": "RNF123", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A7T1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7T1" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1A7T1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7T1" } ] } ] }, { "uniprot_ac": "A0A8V1A9M0", "gene_name": "RNF34", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A9M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9M0" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1A9M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9M0" } ] } ] }, { "uniprot_ac": "A0A8V1A9S5", "gene_name": "NUAK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A9S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9S5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A9S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9S5" } ] } ] }, { "uniprot_ac": "A0A8V1ABF3", "gene_name": "PRKAA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] } ] }, { "uniprot_ac": "A0A8V1ABP4", "gene_name": "DSTYK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP4" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1ABP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP4" } ] } ] }, { "uniprot_ac": "A0A8V1ABR8", "gene_name": "CAMK4L", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR8" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1ABR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR8" } ] } ] }, { "uniprot_ac": "A0A8V1AC19", "gene_name": "UBA7", "activity": [ { "ec_number": "6.2.1.45", "activity": "ATP + ubiquitin + [E1 ubiquitin-activating enzyme]-L-cysteine = AMP + diphosphate + S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V1AC19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC19" } ] }, { "ec_number": "6.2.1.45", "activity": "", "evidence": [ { "id": "A0A8V1AC19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC19" } ] } ] }, { "uniprot_ac": "A0A8V1AC40", "gene_name": "CDK18", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AC40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC40" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V1AC40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC40" } ] } ] }, { "uniprot_ac": "A0A8V1AC55", "gene_name": "SMURF2", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1AC55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC55" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V1AC55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC55" } ] } ] }, { "uniprot_ac": "A0A8V1ACB5", "gene_name": "MAPK13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACB5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1ACB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACB5" } ] } ] }, { "uniprot_ac": "A0A8V1ACF6", "gene_name": "PIM1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF6" } ] } ] }, { "uniprot_ac": "A0A8V1ACK0", "gene_name": "MAPKAPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK0" } ] } ] }, { "uniprot_ac": "A0A8V1ACU3", "gene_name": "UBE2O", "activity": [ { "ec_number": "2.3.2.24", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E1 ubiquitin-activating enzyme]-L-cysteine + N(6)-monoubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1ACU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACU3" } ] }, { "ec_number": "2.3.2.24", "activity": "", "evidence": [ { "id": "A0A8V1ACU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACU3" } ] } ] }, { "uniprot_ac": "A0A8V1ACW2", "gene_name": "WNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACW2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACW2" } ] } ] }, { "uniprot_ac": "A0A8V1ADF0", "gene_name": "MAP2K2", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF0" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V1ADF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF0" } ] } ] }, { "uniprot_ac": "A0A8V1ADN9", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADN9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1ADN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADN9" } ] } ] }, { "uniprot_ac": "A0A8V1ADT4", "gene_name": "MKNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADT4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ADT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADT4" } ] } ] }, { "uniprot_ac": "A0A8V1AE45", "gene_name": "ERN1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AE45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE45" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AE45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE45" } ] } ] }, { "uniprot_ac": "A0A8V1AEH4", "gene_name": "STK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEH4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEH4" } ] } ] }, { "uniprot_ac": "A0A8V1AFS4", "gene_name": "STKLD1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AFS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFS4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AFS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFS4" } ] } ] }, { "uniprot_ac": "A0A8V1AG70", "gene_name": "LOC100857512", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AG70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG70" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AG70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG70" } ] } ] }, { "uniprot_ac": "A0A8V1AH12", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AH12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH12" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AH12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH12" } ] } ] }, { "uniprot_ac": "A0A8V1AHA8", "gene_name": "NEK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AHA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHA8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AHA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHA8" } ] } ] }, { "uniprot_ac": "A0A8V1AIY7", "gene_name": "AATK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AIY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AIY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIY7" } ] } ] }, { "uniprot_ac": "A0A8V1AJA4", "gene_name": "RPS6KB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AJA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJA4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AJA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJA4" } ] } ] }, { "uniprot_ac": "A0A8V1AKB8", "gene_name": "TRIM32", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1AKB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKB8" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1AKB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKB8" } ] } ] }, { "uniprot_ac": "A0A8V1AKW4", "gene_name": "MAP2K4", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AKW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKW4" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V1AKW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKW4" } ] } ] }, { "uniprot_ac": "A0A8V1AL09", "gene_name": "TRIM37", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1AL09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL09" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1AL09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL09" } ] } ] }, { "uniprot_ac": "A0A8V1ALH0", "gene_name": "RNF213", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1ALH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALH0" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1ALH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALH0" } ] } ] }, { "uniprot_ac": "A0A8V1AM12", "gene_name": "GSG2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AM12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM12" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AM12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM12" } ] } ] }, { "uniprot_ac": "A0A8V1AMK5", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AMK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V1AMK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK5" } ] } ] }, { "uniprot_ac": "A0A8V1AML5", "gene_name": "TRIM50", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1AML5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AML5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1AML5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AML5" } ] } ] }, { "uniprot_ac": "A0A8V1AMQ2", "gene_name": "CAMKK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AMQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ2" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1AMQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ2" } ] } ] }, { "uniprot_ac": "A0A8V1AP60", "gene_name": "KSR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AP60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AP60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP60" } ] } ] }, { "uniprot_ac": "A0A8V1AP69", "gene_name": "TRIM58", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1AP69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP69" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1AP69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP69" } ] } ] }, { "uniprot_ac": "E1BQN6", "gene_name": "PRKCZ", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQN6" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1BQN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQN6" } ] } ] }, { "uniprot_ac": "E1BQV7", "gene_name": "SLK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQV7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BQV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQV7" } ] } ] }, { "uniprot_ac": "E1BUG0", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] } ] }, { "uniprot_ac": "E1BW33", "gene_name": "SMG1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BW33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BW33" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BW33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BW33" } ] } ] }, { "uniprot_ac": "E1BWA3", "gene_name": "PRKCI", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BWA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWA3" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1BWA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWA3" } ] } ] }, { "uniprot_ac": "E1BWT0", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BWT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWT0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BWT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWT0" } ] } ] }, { "uniprot_ac": "E1BX69", "gene_name": "EIF2AK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BX69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BX69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BX69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BX69" } ] } ] }, { "uniprot_ac": "E1BY69", "gene_name": "PIM3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BY69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BY69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY69" } ] } ] }, { "uniprot_ac": "E1BYH2", "gene_name": "TAOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BYH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYH2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BYH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYH2" } ] } ] }, { "uniprot_ac": "E1BZ35", "gene_name": "RNF182", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1BZ35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BZ35" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "E1BZ35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BZ35" } ] } ] }, { "uniprot_ac": "E1C093", "gene_name": "PIK3CG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] } ] }, { "uniprot_ac": "E1C2I2", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C2I2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2I2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C2I2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2I2" } ] } ] }, { "uniprot_ac": "E1C3Q9", "gene_name": "SIAH2", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1C3Q9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C3Q9" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "E1C3Q9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C3Q9" } ] } ] }, { "uniprot_ac": "E1C581", "gene_name": "TBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C581", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C581" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C581", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C581" } ] } ] }, { "uniprot_ac": "E1C656", "gene_name": "HACE1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1C656", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C656" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "E1C656", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C656" } ] } ] }, { "uniprot_ac": "E1C6T4", "gene_name": "PRKD3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C6T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C6T4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1C6T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C6T4" } ] } ] }, { "uniprot_ac": "E1C764", "gene_name": "BMP2K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C764", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C764" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C764", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C764" } ] } ] }, { "uniprot_ac": "E1C848", "gene_name": "MAP3K8", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C848", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C848" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1C848", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C848" } ] } ] }, { "uniprot_ac": "E1C982", "gene_name": "AREL1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1C982", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C982" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "E1C982", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C982" } ] } ] }, { "uniprot_ac": "F1NA68", "gene_name": "CDK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NA68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NA68" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1NA68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NA68" } ] } ] }, { "uniprot_ac": "F1NB57", "gene_name": "PLK2", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NB57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NB57" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "F1NB57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NB57" } ] } ] }, { "uniprot_ac": "F1NBT0", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NBT0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NBT0" } ] } ] }, { "uniprot_ac": "F1NC08", "gene_name": "RNF138", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1NC08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NC08" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "F1NC08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NC08" } ] } ] }, { "uniprot_ac": "F1NCX7", "gene_name": "PLK1", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NCX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCX7" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "F1NCX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCX7" } ] } ] }, { "uniprot_ac": "F1NCY7", "gene_name": "MAPKAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NCY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NCY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCY7" } ] } ] }, { "uniprot_ac": "F1NJH1", "gene_name": "PRKCH", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NJH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJH1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1NJH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJH1" } ] } ] }, { "uniprot_ac": "F1NKW3", "gene_name": "MAP3K15", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NKW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NKW3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1NKW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NKW3" } ] } ] }, { "uniprot_ac": "F1NL19", "gene_name": "CDC34", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "F1NL19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NL19" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "F1NL19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NL19" } ] } ] }, { "uniprot_ac": "F1NL77", "gene_name": "CBLB", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1NL77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NL77" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "F1NL77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NL77" } ] } ] }, { "uniprot_ac": "F1NLR7", "gene_name": "CLK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NLR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLR7" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "F1NLR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLR7" } ] } ] }, { "uniprot_ac": "F1NRC6", "gene_name": "RLIM", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1NRC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NRC6" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "F1NRC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NRC6" } ] } ] }, { "uniprot_ac": "F1NTZ8", "gene_name": "HECW2", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1NTZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NTZ8" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "F1NTZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NTZ8" } ] } ] }, { "uniprot_ac": "F1NUX4", "gene_name": "MTOR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NUX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NUX4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NUX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NUX4" } ] } ] }, { "uniprot_ac": "F1NVF2", "gene_name": "MAP2K6", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NVF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVF2" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "F1NVF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVF2" } ] } ] }, { "uniprot_ac": "F1NVY8", "gene_name": "LNX1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1NVY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVY8" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "F1NVY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVY8" } ] } ] }, { "uniprot_ac": "F1P011", "gene_name": "CAMK2A", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1P011", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P011" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F1P011", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P011" } ] } ] }, { "uniprot_ac": "F1P2G0", "gene_name": "SIAH1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1P2G0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P2G0" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "F1P2G0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P2G0" } ] } ] }, { "uniprot_ac": "F1P356", "gene_name": "NUAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1P356", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P356" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1P356", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P356" } ] } ] }, { "uniprot_ac": "F1P4G3", "gene_name": "HIPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1P4G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P4G3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1P4G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P4G3" } ] } ] }, { "uniprot_ac": "P05625", "gene_name": "RAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05625", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05625" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P05625", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05625" } ] } ] }, { "uniprot_ac": "P10741", "gene_name": "MOS", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P10741", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P10741" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P10741", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P10741" } ] } ] }, { "uniprot_ac": "P13863", "gene_name": "CDK1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13863" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13863" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13863" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13863" } ] } ] }, { "uniprot_ac": "P18652", "gene_name": "RPS6KA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P18652", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18652" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P18652", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18652" } ] } ] }, { "uniprot_ac": "P21868", "gene_name": "CSNK2A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P21868", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21868" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P21868", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21868" } ] } ] }, { "uniprot_ac": "P21869", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P21869", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21869" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P21869", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21869" } ] } ] }, { "uniprot_ac": "P53666", "gene_name": "LIMK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P53666", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P53666" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P53666", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P53666" } ] } ] }, { "uniprot_ac": "P67962", "gene_name": "CSNK1A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P67962", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67962" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P67962", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67962" } ] } ] }, { "uniprot_ac": "P79996", "gene_name": "MAPK9", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P79996", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P79996" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P79996", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P79996" } ] } ] }, { "uniprot_ac": "Q04982", "gene_name": "BRAF", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q04982", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q04982" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q04982", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q04982" } ] } ] }, { "uniprot_ac": "Q0GGW5", "gene_name": "STK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0GGW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0GGW5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0GGW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0GGW5" } ] } ] }, { "uniprot_ac": "Q5F3L1", "gene_name": "RPS6KA5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5F3L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3L1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5F3L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3L1" } ] } ] }, { "uniprot_ac": "Q5F3W3", "gene_name": "MAPK6", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5F3W3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3W3" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "Q5F3W3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3W3" } ] } ] }, { "uniprot_ac": "Q5ZIU3", "gene_name": "DYRK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5ZIU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZIU3" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q5ZIU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZIU3" } ] } ] }, { "uniprot_ac": "Q5ZJH6", "gene_name": "ULK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5ZJH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJH6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5ZJH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJH6" } ] } ] }, { "uniprot_ac": "Q5ZJK4", "gene_name": "STK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5ZJK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJK4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5ZJK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJK4" } ] } ] }, { "uniprot_ac": "Q5ZJS0", "gene_name": "CSNK1G1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5ZJS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJS0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5ZJS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJS0" } ] } ] }, { "uniprot_ac": "Q5ZKI0", "gene_name": "CAMK2D", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5ZKI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKI0" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q5ZKI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKI0" } ] } ] }, { "uniprot_ac": "Q5ZKN1", "gene_name": "CDK9", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5ZKN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKN1" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "Q5ZKN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKN1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q5ZKN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKN1" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "Q5ZKN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKN1" } ] } ] }, { "uniprot_ac": "Q5ZKX6", "gene_name": "UBE2F", "activity": [ { "ec_number": "2.3.2.34", "activity": "[E1 NEDD8-activating enzyme]-S-[NEDD8 protein]-yl-L-cysteine + [E2 NEDD8-conjugating enzyme]-L-cysteine = [E1 NEDD8-activating enzyme]-L-cysteine + [E2 NEDD8-conjugating enzyme]-S-[NEDD8-protein]-yl-L-cysteine.", "evidence": [ { "id": "Q5ZKX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKX6" } ] }, { "ec_number": "2.3.2.34", "activity": "", "evidence": [ { "id": "Q5ZKX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKX6" } ] } ] }, { "uniprot_ac": "Q5ZLL1", "gene_name": "CSNK1E", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5ZLL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZLL1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5ZLL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZLL1" } ] } ] }, { "uniprot_ac": "Q6U1I9", "gene_name": "SGK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q6U1I9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6U1I9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q6U1I9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6U1I9" } ] } ] }, { "uniprot_ac": "Q6XUX0", "gene_name": "DSTYK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q6XUX0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6XUX0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q6XUX0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6XUX0" } ] } ] }, { "uniprot_ac": "Q7T0B1", "gene_name": "STK40", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q7T0B1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q7T0B1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q7T0B1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q7T0B1" } ] } ] }, { "uniprot_ac": "Q8AYC9", "gene_name": "CHEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q8AYC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8AYC9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8AYC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8AYC9" } ] } ] }, { "uniprot_ac": "Q8QFP8", "gene_name": "LIMK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q8QFP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8QFP8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8QFP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8QFP8" } ] } ] }, { "uniprot_ac": "Q8QGX4", "gene_name": "PRKDC", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q8QGX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8QGX4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8QGX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8QGX4" } ] } ] }, { "uniprot_ac": "Q90771", "gene_name": "CDK6", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q90771", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q90771" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q90771", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q90771" } ] } ] }, { "uniprot_ac": "Q90891", "gene_name": "MAP2K2", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q90891", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q90891" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "Q90891", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q90891" } ] } ] }, { "uniprot_ac": "Q9I9E0", "gene_name": "TAOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q9I9E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9I9E0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9I9E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9I9E0" } ] } ] }, { "uniprot_ac": "Q9IA88", "gene_name": "SIK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q9IA88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9IA88" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9IA88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9IA88" } ] } ] }, { "uniprot_ac": "R4GIN8", "gene_name": "PRKACB", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "R4GIN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GIN8" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "R4GIN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GIN8" } ] } ] }, { "uniprot_ac": "R4GIV8", "gene_name": "UBE2R2", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "R4GIV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GIV8" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "R4GIV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GIV8" } ] } ] }, { "uniprot_ac": "R4GJB8", "gene_name": "TESK1", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "R4GJB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GJB8" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "R4GJB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GJB8" } ] } ] }, { "uniprot_ac": "Z4YJC3", "gene_name": "TRIM71", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Z4YJC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Z4YJC3" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "Z4YJC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Z4YJC3" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.7.11.1", "ec_name": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "2.7.11.1", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1" }, { "id": "2.7.11.1", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.7.11.1" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1045, "end_pos": 1047 }, { "start_pos": 1255, "end_pos": 1257 }, { "start_pos": 1298, "end_pos": 1300 }, { "start_pos": 1334, "end_pos": 1336 }, { "start_pos": 298, "end_pos": 300 }, { "start_pos": 312, "end_pos": 314 }, { "start_pos": 440, "end_pos": 442 }, { "start_pos": 614, "end_pos": 616 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A7R3-1", "uniprot_ac": "A0A8V1A7R3", "uniprot_id": "A0A8V1A7R3_CHICK", "mass": { "chemical_mass": 40459.0, "monoisotopic_mass": 40459.0 }, "refseq": { "ac": "XP_004935032", "name": "hematopoietic progenitor cell antigen CD34 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004935032" }, "gene_names": [ { "name": "CD34", "type": "recommended", "evidence": [ { "id": "A0A8V1A7R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7R3" } ] }, { "name": "CD34", "type": "synonym", "evidence": [ { "id": "XP_004935032", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004935032" } ] } ], "protein_names": [ { "name": "CD34 molecule", "type": "synonym", "evidence": [ { "id": "A0A8V1A7R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7R3/entry#names_and_taxonomy" } ] }, { "name": "hematopoietic progenitor cell antigen CD34 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_004935032", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004935032" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052557.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004935032.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004935032", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004935032" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7R3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7R3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CD34", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7R3", "locus": { "chromosome": "26", "start_pos": 2760033, "end_pos": 2772836, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027183", "url": "https://www.ensembl.org/id/ENSGALG00010027183" } ] } } ], "crossref": [ { "id": "A0A8V1A7R3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A7R3", "database": "AlphaFoldDB", "categories": [] }, { "id": "419856", "url": "https://www.ncbi.nlm.nih.gov/gene/419856", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR008083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013836", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013836", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:419856", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419856", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GEIKCAG", "url": "https://omabrowser.org/oma/group/GEIKCAG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A7R3", "url": "https://www.orthodb.org/?gene=A0A8V1A7R3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AD53", "url": "https://www.orthodb.org/?gene=A0A8V1AD53", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16677", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16677", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16677:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16677:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06365", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06365", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004935032", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004935032", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1A7R3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7R3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A7R3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7R3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AD53", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD53", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AD53-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD53-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPCWGSVHMMKWRQLFWIVFCTVRLAGTAADSPTDISTAVSLAVATAQSSTGSEAPTSTMGSSTTPMQDSPAATAQPSSVSPISPGLSSGHSPQSSAHPSVHPSVHPSTHPSAQTSAQTSIQTSQTPTPLLGSHSHPENTSSWATTTPSPTLHPGTTAAVHPSATTLLSSTATPRLTVVSEATTQLHTSGGVSKPITCHNIKDVSNSGALCLRLNESHTCKHFLDTKGSDLWSAICEGDADRVPPPCHIKLATSEVDQECLLLILDGNTDPATDVLRKSHWEKFGIKSLERGSVRSHQDFSRKTLTALVTSGLLLAALGTAGYFLMRRRSWSPAGQRLDEDHYDLETGSQGSPAQQEKPSANGAQENGASRNGRGTAQSLADTSM", "length": 385, "header": "tr|A0A8V1A7R3-1|A0A8V1A7R3_CHICK Isoform 1 of CD34 molecule OS=Gallus gallus OX=9031 GN=CD34 PE=1 SV=1 CANONICAL=A0A8V1A7R3-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A7R3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7R3/entry#A0A8V1A7R3-1", "sequence": { "sequence": "MPCWGSVHMMKWRQLFWIVFCTVRLAGTAADSPTDISTAVSLAVATAQSSTGSEAPTSTMGSSTTPMQDSPAATAQPSSVSPISPGLSSGHSPQSSAHPSVHPSVHPSTHPSAQTSAQTSIQTSQTPTPLLGSHSHPENTSSWATTTPSPTLHPGTTAAVHPSATTLLSSTATPRLTVVSEATTQLHTSGGVSKPITCHNIKDVSNSGALCLRLNESHTCKHFLDTKGSDLWSAICEGDADRVPPPCHIKLATSEVDQECLLLILDGNTDPATDVLRKSHWEKFGIKSLERGSVRSHQDFSRKTLTALVTSGLLLAALGTAGYFLMRRRSWSPAGQRLDEDHYDLETGSQGSPAQQEKPSANGAQENGASRNGRGTAQSLADTSM", "length": 385, "header": "tr|A0A8V1A7R3-1|A0A8V1A7R3_CHICK Isoform 1 of CD34 molecule OS=Gallus gallus OX=9031 GN=CD34 PE=1 SV=1 CANONICAL=A0A8V1A7R3-1" }, "locus": { "chromosome": "26", "start_pos": 2772765, "end_pos": 2763510, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065906.1", "url": "https://www.ensembl.org/id/ENSGALT00010065906.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040172.1", "url": "https://www.ensembl.org/id/ENSGALP00010040172.1" } ] } }, { "isoform_ac": "A0A8V1AD53-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7R3/entry#A0A8V1AD53-1", "sequence": { "sequence": "MPCWGSVHMMKWRQLFWIVFCTVRLAGTAADSPTDISTAVSLAVATAQSSTGSEAPTSTMGSSTTPMQDSPATAQPSSVSPISPGLSSGHSPQSSAHPSVHPSVHPSTHPSAQTSAQTSIQTSQTPTPLLGSHSHPENTSSWATTTPSPTLHPGTTAAVHPSATTLLSSTATPRLTVVSEATTQLHTSGGVSKPITCHNIKDVSNSGALCLRLNESHTCKHFLDTKGSDLWSAICEGDADRVPPPCHIKLATSEVDQECLLLILDGNTDPATDVLRKSHWEKFGIKSLERGSVRSHQDFSRKTLTALVTSGLLLAALGTAGYFLMRRRSWSPAG", "length": 334, "header": "tr|A0A8V1AD53-1|A0A8V1AD53_CHICK Computationally mapped isoform of CD34 molecule OS=Gallus gallus OX=9031 GN=CD34 PE=1 SV=1 CANONICAL=A0A8V1A7R3-1" }, "locus": { "chromosome": "26", "start_pos": 2772765, "end_pos": 2763649, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065907.1", "url": "https://www.ensembl.org/id/ENSGALT00010065907.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040173.1", "url": "https://www.ensembl.org/id/ENSGALP00010040173.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:419856", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419856", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1LL53-1", "protein_name": "CD34 molecule", "gene_name": "CD34", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MMLGRRGARAGRGMVRGWTALCLLSLLPSMEFTQTPMAATTATVSASPEISSPVPTTTFDWRSMNSSTFRSTSLYDVSQDSNGTTAVTLVPASTDSFTSTSETLPASGAVNSSVQSQTSLATTVSSTLISFATSEATLQPSTFPGNISDSLYNSTSPVTFSIITSPSFSPTQSILKSEIKCSRVKEVKLAHSICLKLNETSSCEEFKKNNEEKLTGFLCQKKQAEVCSLLLAQSEVRPQCLLLVLTNRTESSSKIKLLEEHRSDLREMGIEDISEEVVSSHQSYSRKTLIALVTSGILLAILITTCYFLMNRRSWSPTGERLGEDPYYVENGGGQGYSSGPEASPEAQGKAIVNRGAQENGTGQATSRNGHSARQRVVADTEL", "length": 383 }, "evidence": [ { "id": "A0A8V1A7R3", "url": "https://omabrowser.org/oma/group/A0A8V1A7R3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "B1PLB1-1", "protein_name": "CD34 molecule", "gene_name": "Cd34", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPVHRGARAGLLLPWGWVALCLMSLLHLNNLTSVASENSTQGVFPPVPTNESTEESITSSIPGSTSHYYLIGQDSNKTTPAISETTVNFTATPGTPSGSGTPHTFSQPQTYPTVTLPTTSDSTSTPEVEHSTWNTSLPSVNVSDYSPNNVSSEMISTTEPCAHTSSSVPSIIKGDIKCSGIRGVPFTQGICLELSEASSCEEFKKERGEELMQILCKKEETEADAGTSVCSLNLAQSEVRPECLLMVLANSTELSSKLQLMEKHQSDLRKLGIQSFNKQDLGSHQSYSRKTLIALVTSGVLLAILGTTGYFLMNRRSWSPTGERLELEP", "length": 329 }, "evidence": [ { "id": "A0A8V1A7R3", "url": "https://omabrowser.org/oma/group/A0A8V1A7R3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3ID98-1", "protein_name": "Hematopoietic progenitor cell antigen CD34", "gene_name": "Cd34", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MQVHRDAHAGLLLPWGWVALCLMSLLHLNNLTSAATETTAPGISPSIPTNESTEKTTIPNIPGSTSSHFLPQDSNETTPAISETTVNFTSTSGIPSGSGTTQTFVQSQTSPTITVPTTSDSASTSEITWKPSLPSVNVSDYSTNNISSEMTPTTEPYAYTSSSTAPVTIKGEIKCSGIREVRLAQGICLELSEASSCDEFKKEKGDGLTQILCGKEGTEVEAGASVCSLLLAQSEVRPECLLMVLANSTELSSKLQLMEKHQSDLRKLGIQGFNKQDIGSHQSYSRKTLIALVTSGVLLAILGTTGYFLMNRRSWSPTGERLGEDPYYTENGGGQGYSSGPGASPETQGKASVIRGAQENGTGQATSRNGHSARQHVVADTEL", "length": 383 }, "evidence": [ { "id": "A0A8V1A7R3", "url": "https://omabrowser.org/oma/group/A0A8V1A7R3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P28906-1", "protein_name": "Hematopoietic progenitor cell antigen CD34", "gene_name": "CD34", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLVRRGARAGPRMPRGWTALCLLSLLPSGFMSLDNNGTATPELPTQGTFSNVSTNVSYQETTTPSTLGSTSLHPVSQHGNEATTNITETTVKFTSTSVITSVYGNTNSSVQSQTSVISTVFTTPANVSTPETTLKPSLSPGNVSDLSTTSTSLATSPTKPYTSSSPILSDIKAEIKCSGIREVKLTQGICLEQNKTSSCAEFKKDRGEGLARVLCGEEQADADAGAQVCSLLLAQSEVRPQCLLLVLANRTEISSKLQLMKKHQSDLKKLGILDFTEQDVASHQSYSQKTLIALVTSGALLAVLGITGYFLMNRRSWSPTGERLGEDPYYTENGGGQGYSSGPGTSPEAQGKASVNRGAQENGTGQATSRNGHSARQHVVADTEL", "length": 385 }, "evidence": [ { "id": "A0A8V1A7R3", "url": "https://omabrowser.org/oma/group/A0A8V1A7R3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q64314-1", "protein_name": "Hematopoietic progenitor cell antigen CD34", "gene_name": "Cd34", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQVHRDTRAGLLLPWRWVALCLMSLLHLNNLTSATTETSTQGISPSVPTNESVEENITSSIPGSTSHYLIYQDSSKTTPAISETMVNFTVTSGIPSGSGTPHTFSQPQTSPTGILPTTSDSISTSEMTWKSSLPSINVSDYSPNNSSFEMTSPTEPYAYTSSSAPSAIKGEIKCSGIREVRLAQGICLELSEASSCEEFKKEKGEDLIQILCEKEEAEADAGASVCSLLLAQSEVRPECLLMVLANSTELPSKLQLMEKHQSDLRKLGIQSFNKQDIGSHQSYSRKTLIALVTSGVLLAILGTTGYFLMNRRSWSPTGERLGEDPYYTENGGGQGYSSGPGASPETQGKANVTRGAQENGTGQATSRNGHSARQHVVADTEL", "length": 382 }, "evidence": [ { "id": "A0A8V1A7R3", "url": "https://omabrowser.org/oma/group/A0A8V1A7R3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 19, "go_terms": [ { "name": "negative regulation of interleukin-2 production", "id": "GO:0032703", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032703", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7R3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7R3" } ], "pmid": "" }, { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7R3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7R3" } ], "pmid": "" }, { "name": "tissue homeostasis", "id": "GO:0001894", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001894", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7R3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7R3" } ], "pmid": "" }, { "name": "positive regulation of angiogenesis", "id": "GO:0045766", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045766", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7R3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7R3" } ], "pmid": "" }, { "name": "cell-matrix adhesion", "id": "GO:0007160", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007160", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7R3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7R3" } ], "pmid": "" }, { "name": "cell-cell adhesion", "id": "GO:0098609", "url": 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"https://www.ebi.ac.uk/QuickGO/term/GO:0003094", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7R3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7R3" } ], "pmid": "" }, { "name": "hematopoietic stem cell proliferation", "id": "GO:0071425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071425", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7R3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7R3" } ], "pmid": "" }, { "name": "paracrine signaling", "id": "GO:0038001", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038001", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7R3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7R3" } ], "pmid": "" }, { "name": "transdifferentiation", "id": "GO:0060290", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060290", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7R3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7R3" } ], "pmid": "" }, { "name": "vascular wound healing", "id": "GO:0061042", "url": 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"metanephric glomerular mesangial cell differentiation", "id": "GO:0072254", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072254", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7R3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7R3" } ], "pmid": "" }, { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7R3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7R3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7R3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7R3" } ], "pmid": "" }, { "name": "external side of plasma membrane", "id": "GO:0009897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009897", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7R3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7R3" } ], "pmid": "" }, { "name": "intercellular bridge", "id": "GO:0045171", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045171", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7R3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7R3" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7R3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7R3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "carbohydrate binding", "id": "GO:0030246", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030246", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7R3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7R3" } ], "pmid": "" }, { "name": "RNA polymerase II-specific DNA-binding transcription factor binding", "id": "GO:0061629", "url": 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"table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A7S4-1", "uniprot_ac": "A0A8V1A7S4", "uniprot_id": "A0A8V1A7S4_CHICK", "mass": { "chemical_mass": 62415.0, "monoisotopic_mass": 62415.0 }, "refseq": { "ac": "XP_015142323", "name": "E3 ubiquitin-protein ligase ZFP91", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015142323" }, "gene_names": [ { "name": "ZFP91", "type": "recommended", "evidence": [ { "id": "A0A8V1A7S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7S4" } ] }, { "name": "ZFP91", "type": "synonym", "evidence": [ { "id": "XP_015142323", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015142323" } ] } ], "protein_names": [ { "name": "E3 ubiquitin-protein ligase ZFP91", "type": "recommended", "evidence": [ { "id": "A0A8V1A7S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7S4/entry#names_and_taxonomy" } ] }, { "name": "2.3.2.27", "type": "synonym", "evidence": [ { "id": "A0A8V1A7S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7S4/entry#names_and_taxonomy" } ] }, { "name": "E3 ubiquitin-protein ligase ZFP91", "type": "synonym", "evidence": [ { "id": "XP_015142323", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015142323" } ] }, { "name": "RING-type E3 ubiquitin transferase ZFP91", "type": "synonym", "evidence": [ { "id": "A0A8V1A7S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7S4/entry#names_and_taxonomy" } ] }, { "name": "Zinc finger protein 91 homolog", "type": "synonym", "evidence": [ { "id": "A0A8V1A7S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7S4/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052536.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015142323.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015142323", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015142323" } ] }, { "annotation": "DNA-binding transcription factor. Also acts as an atypical E3 ubiquitin-protein ligase that mediates 'Lys-63'-linked ubiquitination of MAP3K14/NIK, leading to stabilize and activate MAP3K14/NIK. It thereby acts as an activator of the non-canonical NF-kappa-B2/NFKB2 pathway. May also play an important role in cell proliferation and/or anti-apoptosis.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7S4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7S4#function" }, { "database": "UniProtKB", "id": "ARBA00094191", "url": "https://www.uniprot.org/uniprotkb/ARBA00094191#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7S4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7S4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ZFP91", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7S4", "locus": { "chromosome": "5", "start_pos": 16477322, "end_pos": 16492217, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010026112", "url": "https://www.ensembl.org/id/ENSGALG00010026112" } ] } } ], "crossref": [ { "id": "A0A8V1A7S4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A7S4", "database": "AlphaFoldDB", "categories": [] }, { "id": "423128", "url": "https://www.ncbi.nlm.nih.gov/gene/423128", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051061", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051061", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:423128", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423128", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YCSGAER", "url": "https://omabrowser.org/oma/group/YCSGAER/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A7S4", "url": "https://www.orthodb.org/?gene=A0A8V1A7S4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46179", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46179", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46179:SF11", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46179:SF11", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015142323", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015142323", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1A7S4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7S4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A7S4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7S4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPAGAEQPAGAEQQQEPQQEPQQEPARSPPPAAERPPPPSGRRRPCAAATAEQGEESGGGGRVLRGGRERGRAAGGAAASRRRKAEYPRRRRSSPGARPAAAEQPAAETPSAARKGAPRAGCTDKASGKDPKEEKEEEEVSPALSQGSPVSTARPSRSWRSSRSASAARQREAENSRASRSKTGSLQLVCKSEPNADQLEYEVTEEHQSPAGISDDEEEILASEEEVPFKDDPRDETYKPHLEKEAPKQRRKAGKGKEEKEKQKEIKVEVKEESEFREDEEPPRKRGRRRKDDKSPRLPKRRKKPPIQYVRCEMEGCGTVLAHPRYLQHHIKYQHLLKKKYVCPHPSCGRLFRLQKQLLRHAKHHTDQRDYICEYCARAFKSSHNLAVHRMIHTGEKPLQCEICGFTCRQKASLNWHMKKHDADSFYQFSCNICGKKFEKKDSVVAHKAKSHPEVLIAEALAANAGALITSTDILGTNPEAIAPPTDGQGLPLLPDPLGSAAPADCLLLNPDGMPKTYCGGAERVSLVADGKLFVGSGSSANPEGLVMNTEILGATTEVLIEDSDSTGP", "length": 569, "header": "tr|A0A8V1A7S4-1|A0A8V1A7S4_CHICK Isoform 1 of E3 ubiquitin-protein ligase ZFP91 OS=Gallus gallus OX=9031 GN=ZFP91 PE=3 SV=1 CANONICAL=A0A8V1A7S4-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A7S4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7S4/entry#A0A8V1A7S4-1", "sequence": { "sequence": "MPAGAEQPAGAEQQQEPQQEPQQEPARSPPPAAERPPPPSGRRRPCAAATAEQGEESGGGGRVLRGGRERGRAAGGAAASRRRKAEYPRRRRSSPGARPAAAEQPAAETPSAARKGAPRAGCTDKASGKDPKEEKEEEEVSPALSQGSPVSTARPSRSWRSSRSASAARQREAENSRASRSKTGSLQLVCKSEPNADQLEYEVTEEHQSPAGISDDEEEILASEEEVPFKDDPRDETYKPHLEKEAPKQRRKAGKGKEEKEKQKEIKVEVKEESEFREDEEPPRKRGRRRKDDKSPRLPKRRKKPPIQYVRCEMEGCGTVLAHPRYLQHHIKYQHLLKKKYVCPHPSCGRLFRLQKQLLRHAKHHTDQRDYICEYCARAFKSSHNLAVHRMIHTGEKPLQCEICGFTCRQKASLNWHMKKHDADSFYQFSCNICGKKFEKKDSVVAHKAKSHPEVLIAEALAANAGALITSTDILGTNPEAIAPPTDGQGLPLLPDPLGSAAPADCLLLNPDGMPKTYCGGAERVSLVADGKLFVGSGSSANPEGLVMNTEILGATTEVLIEDSDSTGP", "length": 569, "header": "tr|A0A8V1A7S4-1|A0A8V1A7S4_CHICK Isoform 1 of E3 ubiquitin-protein ligase ZFP91 OS=Gallus gallus OX=9031 GN=ZFP91 PE=3 SV=1 CANONICAL=A0A8V1A7S4-1" }, "locus": { "chromosome": "5", "start_pos": 16492018, "end_pos": 16480275, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063621.1", "url": "https://www.ensembl.org/id/ENSGALT00010063621.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039272.1", "url": "https://www.ensembl.org/id/ENSGALP00010039272.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:423128", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423128", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1MAJ8-1", "protein_name": "E3 ubiquitin-protein ligase ZFP91", "gene_name": "Zfp91", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPGETEEPRSPEQQDQEGGPAAAADAASDELRSGVAAAAKPAETASSRVLRGGRDRGRTAAAAAAAAVSRRRKAEYPRRRRSSPSNRPPDGHGHQPAAAKPPSPAQGKKSPRLQCIEKITTDKDPKEEKEDDSVLPQEVSITATRPSRSWRSSSRTSISRLRDSENTRSSRSKTGSLQLVCKTEPITDQLDYDVPEEHQSPSGISSDEEEEEEEMLISEEEIPFKDDPRDETYKPHLERETPKPRRKSGKVKEEKEKKEIKVEVEVEVKEEENEIREDEEPPRKRGRRRKDDKSPRLPKRRKKPPIQYVRCEMEGCGTVLAHPRYLQHHIKYQHLLKKKYVCPHPSCGRLFRLQKQLLRHAKHHTDQRDYICEYCARAFKSSHNLAVHRMIHTGEKPLQCEICGFTCRQKASLNWHMKKHDADSFYQFSCNICGKKFEKKDSVVAHKAKSHPEVLIAEALAANAGALITSTDILGTNPEPLTQPADSQGLPLLPEPLGNSTSGECLLLEAEGMSKSYCSGTERVSLMADGKIFVGSGSSGGTEGLVMNSDILGATTEVLIEDTDSTGP", "length": 568 }, "evidence": [ { "id": "A0A8V1A7S4", "url": "https://omabrowser.org/oma/group/A0A8V1A7S4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1MV04-1", "protein_name": "E3 ubiquitin-protein ligase ZFP91", "gene_name": "ZFP91", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPGETEEPRPPERQDQGGGPAAAEPQPQPPEAAAAPPAGPPSSRVLRGGRDRGRAAAAAAAAAAAVSRRRKAEYPRRRRSSPSARPADAPGQPAQAAKPPSPAQGKRSPRLLCIEKVSTEKDPKEEKEEEESALAQEAPSATARPSRGWRGSSRTSVSRHRDAENTRSSRSKTGSLQLICKSEPNTDQLDYDAAEEHQSPGGISSDEEEEEEEEMLISEEEIPFKDDPRDETYKPHLERETPKPRRKSGKVKEEKEKKEIKVEVEVEVKEEENEIREDEEPPRKRGRRRKDDKSPRLPKRRKKPPIQYVRCEMEGCGTVLAHPRYLQHHIKYQHLLKKKYVCPHPSCGRLFRLQKQLLRHAKHHTDQRDYICEYCARAFKSSHNLAVHRMIHTGEKPLQCEICGFTCRQKASLNWHMKKHDADSFYQFSCNICGKKFEKKDSVVAHKAKSHPEVLIAEALAANAGALITSTDILGTSPEALSPPAGGQGLPLLPEPLGNPAPGECLLLEAEGVSKSFCGGAERVSLVTDGKLFVGGGGGTGADGLVMNSDILGATAEVLIEDSDSAGP", "length": 568 }, "evidence": [ { "id": "A0A8V1A7S4", "url": "https://omabrowser.org/oma/group/A0A8V1A7S4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q62511-1", "protein_name": "E3 ubiquitin-protein ligase ZFP91", "gene_name": "Zfp91", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPGETEEPRSPEQQDQEGGPAAAADAASEELRPGAAAAPAAPAETASSRVLRGGRDRGRTAAAAAAAAAAVSRRRKAEYPRRRRSSPSNRPPDGPGHQPAAAKPPSPAQGKKSPRLQCIEKLTTDKDPKEEKEDDSVLPQEVSITTTRASRSWRSSSRTSISRLRDSENTRSSRSKTGSLQLVCKTEPITDQLDYDVPEEHQSPGGISSDEEEEEEEEMLISEEEIPFKDDPRDETYKPHLERETPKPRRKSGKVKEEKEKKEIKVEVEVEVKEEENEIREDEEPPRKRGRRRKDDKSPRLPKRRKKPPIQYVRCEMEGCGTVLAHPRYLQHHIKYQHLLKKKYVCPHPSCGRLFRLQKQLLRHAKHHTDQRDYICEYCARAFKSSHNLAVHRMIHTGEKPLQCEICGFTCRQKASLNWHMKKHDADSFYQFSCNICGKKFEKKDSVVAHKAKSHPEVLIAEALAANAGALITSTDILGTNPEPLTQPADGQGLPLLPEPLGNSTAGECLLLEAEGMSKSYCSGTERVSLMADGKIFVGSGSSGGTEGLVMNSDILGATTEVLIEDTDSTGP", "length": 572 }, "evidence": [ { "id": "A0A8V1A7S4", "url": "https://omabrowser.org/oma/group/A0A8V1A7S4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96JP5-1", "protein_name": "E3 ubiquitin-protein ligase ZFP91", "gene_name": "ZFP91", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPGETEEPRPPEQQDQEGGEAAKAAPEEPQQRPPEAVAAAPAGTTSSRVLRGGRDRGRAAAAAAAAAVSRRRKAEYPRRRRSSPSARPPDVPGQQPQAAKSPSPVQGKKSPRLLCIEKVTTDKDPKEEKEEEDDSALPQEVSIAASRPSRGWRSSRTSVSRHRDTENTRSSRSKTGSLQLICKSEPNTDQLDYDVGEEHQSPGGISSEEEEEEEEEMLISEEEIPFKDDPRDETYKPHLERETPKPRRKSGKVKEEKEKKEIKVEVEVEVKEEENEIREDEEPPRKRGRRRKDDKSPRLPKRRKKPPIQYVRCEMEGCGTVLAHPRYLQHHIKYQHLLKKKYVCPHPSCGRLFRLQKQLLRHAKHHTDQRDYICEYCARAFKSSHNLAVHRMIHTGEKPLQCEICGFTCRQKASLNWHMKKHDADSFYQFSCNICGKKFEKKDSVVAHKAKSHPEVLIAEALAANAGALITSTDILGTNPESLTQPSDGQGLPLLPEPLGNSTSGECLLLEAEGMSKSYCSGTERVSLMADGKIFVGSGSSGGTEGLVMNSDILGATTEVLIEDSDSAGP", "length": 570 }, "evidence": [ { "id": "A0A8V1A7S4", "url": "https://omabrowser.org/oma/group/A0A8V1A7S4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7S4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7S4" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7S4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7S4" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7S4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7S4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7S4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7S4" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7S4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7S4" } ], "pmid": "" }, { "name": "protein K63-linked ubiquitination", "id": "GO:0070534", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070534", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7S4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7S4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7S4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7S4" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7S4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7S4" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7S4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7S4" } ], "pmid": "" }, { "name": "transcription coregulator activity", "id": "GO:0003712", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003712", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7S4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7S4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1A7S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7S4" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 341, "end_pos": 370, "start_aa": "Tyr", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.3.2.27", "ec_name": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "2.3.2.27", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.3.2.27" } ] } ], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": 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"o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A7S7-1", "uniprot_ac": "A0A8V1A7S7", "uniprot_id": "A0A8V1A7S7_CHICK", "mass": { "chemical_mass": 12316.0, "monoisotopic_mass": 12316.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Ig-like domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8V1A7S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7S7/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7S7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7S7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7S7", "locus": {} } ], "crossref": [ { "id": "A0A8V1A7S7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A7S7", "database": 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"categories": [ "Protein Classification" ] }, { "id": "IPR050636", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050636", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR47772", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47772", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47772:SF12", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47772:SF12", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47772:SF13", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47772:SF13", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01352", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01352", "database": "Pfam", "categories": [ "Protein 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"https://www.ensembl.org/id/ENSGALT00010065936.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040202.1", "url": "https://www.ensembl.org/id/ENSGALP00010040202.1" } ] } }, { "isoform_ac": "A0A8V1AAF1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7U3/entry#A0A8V1AAF1-1", "sequence": { "sequence": "GPGASHDVAVYFSAEEWLLLARWQRELYQEVMMDNYDLVACLGKEQCCAAPPAPPAPGAPLLTLHPSFRGAPRCALPGAGGVRRGLRGRRSAGSLSLIRHGAQHGEERPFACGRCERRFSWKESLQLHLRSHAPERRHKCQQCGRAFSRSGNLLLHQRVHTGERPYACTQCDKAFCNKASLTTHRRLHRRCRTFACAQCRLGFSSKSKLRLHLRGHGDGGGLGVGGGQP", "length": 229, "header": "tr|A0A8V1AAF1-1|A0A8V1AAF1_CHICK Computationally mapped isoform of KRAB domain-containing protein OS=Gallus gallus OX=9031 GN= PE=3 SV=1 CANONICAL=A0A8V1A7U3-1" }, "locus": { "chromosome": "2", "start_pos": 398891, "end_pos": 397157, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065933.1", "url": "https://www.ensembl.org/id/ENSGALT00010065933.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040199.1", "url": "https://www.ensembl.org/id/ENSGALP00010040199.1" } ] } }, { "isoform_ac": "A0A8V1AD83-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7U3/entry#A0A8V1AD83-1", "sequence": { "sequence": "PRPQVHPCSHCIPVCCHDWGWHSSTRHKAAPCTGTRRPGHECTACGKVFRHHRNLLAHKKQRGPQRHPCSECGHSFCLKGDLLRHRHQRDPRAHGEGQKAAAPRLSPECGRRLEAELSLIRHGAQHGEERPFACGRCERRFSWKESLQLHLRSHAPERRHKCQQCGRAFSRSGNLLLHQRVHTGERPYACTQCDKAFCNKASLTTHRRLHRRCRTFACAQCRLGFSSKSKLRLHLHCEGGAGGGVPVPPASTAGPRPATSPNAEPARRPRGTERPFGCGECGKSFQHRGNLITHLRVHTGERPFACGVCGKSFSQKGDLMRHQRTHTGEKPFECTVCGKSFCSKQTFVLHQRIHTGEKPFSCGDCGKSFNRKANFVTHQKIHRGERPFVCAECGKGFCAKKTFILHQKIHVGERPFGCSQCGKSFSRNGDLTRHHRIHTGERPFACADCGKSFSHNGELIKHRRIHTGEKPFACTECGKSFNRKGTLITHQRIHTGERPFVCAECGKSFNLKTTLMKHTRIHTGERPFACAECGKSFKYKGNLRTHRLTHTVQRVYPCTECGQVFGHRKELSAHQGAHAGERVLSCCRPCLPAPPLLVPRTQTQLPLSKCE", "length": 611, "header": "tr|A0A8V1AD83-1|A0A8V1AD83_CHICK Computationally mapped isoform of C2H2-type domain-containing protein OS=Gallus gallus OX=9031 GN= PE=3 SV=1 CANONICAL=A0A8V1A7U3-1" }, "locus": { "chromosome": "2", "start_pos": 403236, "end_pos": 397362, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065937.1", "url": "https://www.ensembl.org/id/ENSGALT00010065937.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040203.1", "url": "https://www.ensembl.org/id/ENSGALP00010040203.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7U3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7U3" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7U3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7U3" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7U3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7U3" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7U3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7U3" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7U3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7U3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7U3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7U3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7U3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7U3" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7U3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7U3" } ], "pmid": "" }, { "name": "negative regulation of DNA-templated transcription", "id": "GO:0045892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045892", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7U3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7U3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1A7U3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7U3" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 157, "end_pos": 184, "start_aa": "His", "end_aa": "His", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1A7U3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7U3" }, { "id": "PS50805", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50805" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "KRAB", "eco_id": "ECO_0000259", "start_pos": 12, "end_pos": 86, "start_aa": "Val", "end_aa": "Cys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AAH3-1", "uniprot_ac": "A0A8V1AAH3", "uniprot_id": "A0A8V1AAH3_CHICK", "mass": { "chemical_mass": 106504.0, "monoisotopic_mass": 106504.0 }, "refseq": {}, "gene_names": [ { "name": "CHAF1A", "type": "recommended", "evidence": [ { "id": "A0A8V1AAH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAH3" } ] } ], "protein_names": [ { "name": "Chromatin assembly factor 1 subunit A", "type": "synonym", "evidence": [ { "id": "A0A8V1AAH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAH3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAH3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAH3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CHAF1A", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAH3", "locus": { "chromosome": "28", "start_pos": 2957931, "end_pos": 2931938, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027202", "url": "https://www.ensembl.org/id/ENSGALG00010027202" } ] } } ], "crossref": [ { "id": "A0A8V1AAH3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AAH3", "database": "AlphaFoldDB", "categories": [] }, { "id": "770217", "url": "https://www.ncbi.nlm.nih.gov/gene/770217", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR021644", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021644", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022043", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022043", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029091", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029091", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029105", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029105", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A7W0", "url": "https://www.orthodb.org/?gene=A0A8V1A7W0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AAH3", "url": "https://www.orthodb.org/?gene=A0A8V1AAH3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ADA2", "url": "https://www.orthodb.org/?gene=A0A8V1ADA2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AFC2", "url": "https://www.orthodb.org/?gene=A0A8V1AFC2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AFC7", "url": "https://www.orthodb.org/?gene=A0A8V1AFC7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15272", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15272", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15272:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15272:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF11600", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11600", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12253", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12253", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF15539", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15539", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF15557", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15557", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1A7W0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7W0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A7W0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7W0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AAH3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAH3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AAH3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAH3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ADA2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADA2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ADA2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADA2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFC2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFC2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFC2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFC7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFC7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFC7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFC7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAMECRDKAVVPPRRLVQARLPFKRLNPVPKEKHDAEAEGKKGKCSKSGLGQSKDSSTDTSHASTDNMENDCQLNSDVNFVPKLVNGKGPLDHFIRKSTKDNTDEIIVIIDSVDESNQRLSDDVDHVSFDSKASSAALTNGMLGKDTNKLSCLNSTQNSQTDDSMQTDVPCEAIANKGEDLVDGIQSCSGLTERNNLENTKVNQSELKDVIFEGKMPVVLLEDIMAAKSPQVTSLDGSVTSENETVELSHEGDSVLTNSSLSSLSVSSPEAQPVAETKRNTSPLAVSTPVRKVSQKLHKSSAEKEKLRLQRDQERADKLQKLQAEREEKGRLKEEAKAAKERAKEEAKKKKEEEKELKERERREKKEKEEKEKAEKLRVKEEKRKERQEALEAKLEEKRKKEEEKRLKEEEKRINAQKAEITRFFQKPKTPQAPKILAGSCGKFAPFEIKENMVLAPLCRIALYPDFLEQLDRLLRAQNSEVSFLRDLKCRKPRKTGPTFVNSSTDTVNSDVVVVDNCKTDAVPERGKFGRMKLLQFCENHRPAYWGTWNKKTTMIRPRNPWSKDSKLLDYEVDSDEEWEEEEPGESLSHSEGDDEEEGEDEDDDDGFFVPHGYLSEDEGVTEECDPENQKVRQKLKAKEWDELMAKGKRLHVLQPVKIGCIWESAQNDSGTNADLKILQQFTACILDSSVAEEEQQIQKCSKKRAKDQQILGQLLPLLHGNVNGSKVIIQEFQECCRQGLFSDVTAATDCGDTSPVSPNTSRPQTPVGEDSGVPSKARLKRIISENSVYEKRPEYRMCWYVHSEVLKSFDQEHLPVPCQWNYITQVPSSGKEDGGSVPGVAPVQSTPVSVKRKSTGSMCITKFMKRPRDAEQAEAMEMDGFQADTEEDEDDDDCMIVDVQPCKDSTLTVTETAPESRGTTAAHQDASMAGSSVCRCLEKMRSNVPAAH", "length": 950, "header": "tr|A0A8V1AAH3-1|A0A8V1AAH3_CHICK Isoform 1 of Chromatin assembly factor 1 subunit A OS=Gallus gallus OX=9031 GN=CHAF1A PE=3 SV=1 CANONICAL=A0A8V1AAH3-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A7W0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAH3/entry#A0A8V1A7W0-1", "sequence": { "sequence": "MAAMECRDKAVVPPRRLVQARLPFKRLNPVPKEKHDAEAEGKKGKCSKSGLGQSKDSSTDTSHASTDNMENDCQLNSDVNFVPKLVNGKGPLDHFIRKSTKDNTDEIIVIIDSVDESNQRLSDDVDHVSFDSKASSAALTNGMLGKDTNKLSCLNSTQNSQTDDSMQTDVPCEAIANKGEDLVDGIQSCSGLTERNNLENTKVNQSELKDVIFEGKMPVVLLEDIMAAKSPQVTSLDGSVTSENETVELSHEGDSVLTNSSLSSLSVSSPEAQPVAETKRNTSPLAVSTPVRKVSQKLHKSSAEKEKLRLQRDQERADKLQKLQAEREEKGRLKEEAKAAKERAKEEKELKERERREKKEKEEKEKAEKLRVKEEKRKERQEALEAKLEEKRKKEEEKRLKEEEKRINAQKAEITRFFQKPKTPQAPKILAGSCGKFAPFEIKENMVLAPLCRIALYPDFLEQLDRLLRAQNSEVSFLRDLKCRKPRKTGPTFVNSSTDTVNSDVVVVDNCKTDAVPERGKFGRMKLLQFCENHRPAYWGTWNKKTTMIRPRNPWSKDSKLLDYEVDSDEEWEEEEPGESLSHSEGDDEEEGEDEDDDDGFFVPHGYLSEDEGVTEECDPENQKVRQKLKAKEWDELMAKGKRLHVLQPVKIGCIWESAQNDSGTNADLKILQQFTACILDSSVAEEEQQIQKCSKKRAKDQQILGQLLPLLHGNVNGSKVIIQEFQECCRQGLFSDVTAATDCGDTSPVSPNTSRPQTPVGEDSGVPSKARLKRIISENSVYEKRPEYRMCWYVHSEVLKSFDQEHLPVPCQWNYITQVPSSGKEDGGSVPGVAPVQSTPVSVKRKSTGSMCITKFMKRPRDAEQAEAMEMDGFQADTEEDEDDDDCMIVDVQPCKDSTLTVTETAPESRGTTAAHQDASMVSPSNTV", "length": 929, "header": "tr|A0A8V1A7W0-1|A0A8V1AAH3_CHICK Computationally mapped isoform of Chromatin assembly factor 1 subunit A OS=Gallus gallus OX=9031 GN=CHAF1A PE=3 SV=1 CANONICAL=A0A8V1AAH3-1" }, "locus": { "chromosome": "28", "start_pos": 2956071, "end_pos": 2942089, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065951.1", "url": "https://www.ensembl.org/id/ENSGALT00010065951.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040217.1", "url": "https://www.ensembl.org/id/ENSGALP00010040217.1" } ] } }, { "isoform_ac": "A0A8V1AAH3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAH3/entry#A0A8V1AAH3-1", "sequence": { "sequence": "MAAMECRDKAVVPPRRLVQARLPFKRLNPVPKEKHDAEAEGKKGKCSKSGLGQSKDSSTDTSHASTDNMENDCQLNSDVNFVPKLVNGKGPLDHFIRKSTKDNTDEIIVIIDSVDESNQRLSDDVDHVSFDSKASSAALTNGMLGKDTNKLSCLNSTQNSQTDDSMQTDVPCEAIANKGEDLVDGIQSCSGLTERNNLENTKVNQSELKDVIFEGKMPVVLLEDIMAAKSPQVTSLDGSVTSENETVELSHEGDSVLTNSSLSSLSVSSPEAQPVAETKRNTSPLAVSTPVRKVSQKLHKSSAEKEKLRLQRDQERADKLQKLQAEREEKGRLKEEAKAAKERAKEEAKKKKEEEKELKERERREKKEKEEKEKAEKLRVKEEKRKERQEALEAKLEEKRKKEEEKRLKEEEKRINAQKAEITRFFQKPKTPQAPKILAGSCGKFAPFEIKENMVLAPLCRIALYPDFLEQLDRLLRAQNSEVSFLRDLKCRKPRKTGPTFVNSSTDTVNSDVVVVDNCKTDAVPERGKFGRMKLLQFCENHRPAYWGTWNKKTTMIRPRNPWSKDSKLLDYEVDSDEEWEEEEPGESLSHSEGDDEEEGEDEDDDDGFFVPHGYLSEDEGVTEECDPENQKVRQKLKAKEWDELMAKGKRLHVLQPVKIGCIWESAQNDSGTNADLKILQQFTACILDSSVAEEEQQIQKCSKKRAKDQQILGQLLPLLHGNVNGSKVIIQEFQECCRQGLFSDVTAATDCGDTSPVSPNTSRPQTPVGEDSGVPSKARLKRIISENSVYEKRPEYRMCWYVHSEVLKSFDQEHLPVPCQWNYITQVPSSGKEDGGSVPGVAPVQSTPVSVKRKSTGSMCITKFMKRPRDAEQAEAMEMDGFQADTEEDEDDDDCMIVDVQPCKDSTLTVTETAPESRGTTAAHQDASMAGSSVCRCLEKMRSNVPAAH", "length": 950, "header": "tr|A0A8V1AAH3-1|A0A8V1AAH3_CHICK Isoform 1 of Chromatin assembly factor 1 subunit A OS=Gallus gallus OX=9031 GN=CHAF1A PE=3 SV=1 CANONICAL=A0A8V1AAH3-1" }, "locus": { "chromosome": "28", "start_pos": 2956927, "end_pos": 2942089, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065954.1", "url": "https://www.ensembl.org/id/ENSGALT00010065954.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040220.1", "url": "https://www.ensembl.org/id/ENSGALP00010040220.1" } ] } }, { "isoform_ac": "A0A8V1ADA2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAH3/entry#A0A8V1ADA2-1", "sequence": { "sequence": "MECRDKAVVPPRRLVQARLPFKRLNPVPKEKHDAEAEGKKGKCSKSGLGQSKDSSTDTSHASTDNMENDCQLNSDVNFVPKLVNGKGPLDHFIRKSTKDNTDEIIVIIDSVDESNQRLSDDVDHVSFDSKASSAALTNGMLGKDTNKLSCLNSTQNSQTDDSMQTDVPCEAIANKGEDLVDGIQSCSGLTERNNLENTKVNQSELKDVIFEGKMPVVLLEDIMAAKSPQVTSLDGSVTSENETVELSHEGDSVLTNSSLSSLSVSSPEAQPVAETKRNTSPLAVSTPVRKVSQKLHKSSAEKEKLRLQRDQERADKLQKLQAEREEKGRLKEEAKAAKERAKEEAKKKKEEEKELKERERREKKEKEEKEKAEKLRVKEEKRKERQEALEAKLEEKRKKEEEKRLKEEEKRINAQKAEITRFFQKPKTPQAPKILAGSCGKFAPFEIKENMVLAPLCRIALYPDFLEQLDRLLRAQNSEVSFLRDLKCRKPRKTGPTFVNSSTDTVNSDVVVVDNCKTDAVPERGKFGRMKLLQFCENHRPAYWGTWNKKTTMIRPRNPWSKDSKLLDYEVDSDEEWEEEEPGESLSHSEGDDEEEGEDEDDDDGFFVPHGYLSEDEGVTEECDPENQKVRQKLKAKEWDELMAKGKRLHVLQPVKIGCIWESAQNDSGTNADLKILQQFTACILDSSVAEEEQQIQKCSKKRAKDQQILGQLLPLLHGNVNGSKVIIQEFQECCRQGLFSDVTAATDCGDTSPVSPNTSRPQTPVGEDSGVPSKARLKRIISENSVYEKRPEYRMCWYVHSEVLKSFDQEHLPVPCQWNYITQVPSSGKEDGGSVPGVAPVQSTPVSVKRKSTGSMCITKFMKRPRDAEQAEAMEMDGFQADTEEDEDDDDCMIVDVQPCKDSTLTVTETAPESRGTTAAHQDASMVSPSNTV", "length": 934, "header": "tr|A0A8V1ADA2-1|A0A8V1ADA2_CHICK Computationally mapped isoform of Chromatin assembly factor 1 subunit A OS=Gallus gallus OX=9031 GN=CHAF1A PE=3 SV=1 CANONICAL=A0A8V1AAH3-1" }, "locus": { "chromosome": "28", "start_pos": 2956071, "end_pos": 2942349, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065953.1", "url": "https://www.ensembl.org/id/ENSGALT00010065953.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040219.1", "url": "https://www.ensembl.org/id/ENSGALP00010040219.1" } ] } }, { "isoform_ac": "A0A8V1AFC2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAH3/entry#A0A8V1AFC2-1", "sequence": { "sequence": "FVAMECRDKAVVPPRRLVQARLPFKRLNPVPKEKHDAEAEGKKGKCSKSGLGQSKDSSTDTSHASTDNMENDCQLNSDVNFVPKLVNGKGPLDHFIRKSTKDNTDEIIVIIDSVDESNQRLSDDVDHVSFDSKASSAALTNGMLGKDTNKLSCLNSTQNSQTDDSMQTDVPCEAIANKGEDLVDGIQSCSGLTERNNLENTKVNQSELKDVIFEGKMPVVLLEDIMAAKSPQVTSLDGSVTSENETVELSHEGDSVLTNSSLSSLSVSSPEAQPVAETKRNTSPLAVSTPVRKVSQKLHKSSAEKEKLRLQRDQERADKLQKLQAEREEKGRLKEEAKAAKERAKEEAKKKKEEEKELKERERREKKEKEEKEKAEKLRVKEEKRKERQEALEAKLEEKRKKEEEKRLKEEEKRINAQKAEITRFFQKPKTPQAPKILAGSCGKFAPFEIKENMVLAPLCRIALYPDFLEQLDRLLRAQNSEVSFLRDLKCRKPRKTGPTFVNSSTDTVNSDVVVVDNCKTDAVPERGKFGRMKLLQFCENHRPAYWGTWNKKTTMIRPRNPWSKDSVSNLQDDEEEGEDEDDDDGFFVPHGYLSEDEGVTEECDPENQKVRQKLKAKEWDELMAKGKRLHVLQPVKIGCIWESAQNDSGTNADLKILQQFTACILDSSVAEEEQQIQKCSKKRAKDQQILGQLLPLLHGNVNGSKVIIQEFQECCRQGLFSDVTAATDCGDTSPVSPNTSRPQTPVGEDSGVPSKARLKRIISENSVYEKRPEYRMCWYVHSEVLKSFDQEHLPVPCQWNYITQVPSSGKEDGGSVPGVAPVQSTPVSVKRKSTGSMCITKFMKRPRDAEQAEAMEMDGFQADTEEDEDDDDCMIVDVQPCKDSTLTVTETAPESRGTTAAHQDASMVSPSNTV", "length": 915, "header": "tr|A0A8V1AFC2-1|A0A8V1AFC2_CHICK Computationally mapped isoform of Chromatin assembly factor 1 subunit A OS=Gallus gallus OX=9031 GN=CHAF1A PE=3 SV=1 CANONICAL=A0A8V1AAH3-1" }, "locus": { "chromosome": "28", "start_pos": 2956071, "end_pos": 2942340, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065950.1", "url": "https://www.ensembl.org/id/ENSGALT00010065950.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040216.1", "url": "https://www.ensembl.org/id/ENSGALP00010040216.1" } ] } }, { "isoform_ac": "A0A8V1AFC7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAH3/entry#A0A8V1AFC7-1", "sequence": { "sequence": "MGHTEQLAMECRDKAVVPPRRLVQARLPFKRLNPVPKEKHDAEAEGKKGKCSKSGLGQSKDSSTDTSHASTDNMENDCQLNSDVNFVPKLVNGKGPLDHFIRKSTKDNTDEIIVIIDSVDESNQRLSDDVDHVSFDSKASSAALTNGMLGKDTNKLSCLNSTQNSQTDDSMQTDVPCEAIANKGEDLVDGIQSCSGLTERNNLENTKVNQSELKDVIFEGKMPVVLLEDIMAAKSPQVTSLDGSVTSENETVELSHEGDSVLTNSSLSSLSVSSPEAQPVAETKRNTSPLAVSTPVRKVSQKLHKSSAEKEKLRLQRDQERADKLQKLQAEREEKGRLKEEAKAAKERAKEEAKKKKEEEKELKERERREKKEKEEKEKAEKLRVKEEKRKERQEALEAKLEEKRKKEEEKRLKEEEKRINAQKAEITRFFQKPKTPQAPKILAGSCGKFAPFEIKENMVLAPLCRIALYPDFLEQLDRLLRAQNSEVSFLRDLKCRKPRKTGPTFVNSSTDTVNSDVVVVDNCKTDAVPERGKFGRMKLLQFCENHRPAYWGTWNKKTTMIRPRNPWSKDSKLLDYEVDSDEEWEEEEPGESLSHSEGDDEEEGEDEDDDDGFFVPHGYLSEDEGVTEECDPENQKVRQKLKAKEWDELMAKGKRLHVLQPVKIGCIWESAQNDSGTNADLKILQQFTACILDSSVAEEEQQIQKCSKKRAKDQQILGQLLPLLHGNVNGSKVIIQEFQECCRQGLFSDVTAATDCGDTSPVSPNTSRPQTPVGEDSGVPSKARLKRIISENSVYEKRPEYRMCWYVHSEVLKSFDQEHLPVPCQWNYITQVPSSGKEDGGSVPGVAPVQSTPVSVKRKSTGSMCITKFMKRPRDAEQAEAMEMDGFQADTEEDEDDDDCMIVDVQPCKDSTLTVTETAPESRGTTAAHQDASMVSPSNTV", "length": 942, "header": "tr|A0A8V1AFC7-1|A0A8V1AFC7_CHICK Computationally mapped isoform of Chromatin assembly factor 1 subunit A OS=Gallus gallus OX=9031 GN=CHAF1A PE=3 SV=1 CANONICAL=A0A8V1AAH3-1" }, "locus": { "chromosome": "28", "start_pos": 2956071, "end_pos": 2932014, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065956.1", "url": "https://www.ensembl.org/id/ENSGALT00010065956.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040222.1", "url": "https://www.ensembl.org/id/ENSGALP00010040222.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAH3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAH3" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAH3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAH3" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAH3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAH3" } ], "pmid": "" }, { "name": "CAF-1 complex", "id": "GO:0033186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033186", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAH3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAH3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAH3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAH3" } ], "pmid": "" }, { "name": "DNA replication", "id": "GO:0006260", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006260", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAH3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAH3" } ], "pmid": "" }, { "name": "nucleosome assembly", "id": "GO:0006334", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006334", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAH3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAH3" } ], "pmid": "" }, { "name": "DNA replication-dependent chromatin assembly", "id": "GO:0006335", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006335", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAH3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAH3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAH3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAH3" } ], "pmid": "" }, { "name": "chromo shadow domain binding", "id": "GO:0070087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070087", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAH3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAH3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 155, "end_pos": 157, "annotation": "n_glycosylation_sequon" }, { "start_pos": 204, "end_pos": 206, "annotation": "n_glycosylation_sequon" }, { "start_pos": 244, "end_pos": 246, "annotation": "n_glycosylation_sequon" }, { "start_pos": 259, "end_pos": 261, "annotation": "n_glycosylation_sequon" }, { "start_pos": 281, "end_pos": 283, "annotation": "n_glycosylation_sequon" }, { "start_pos": 503, "end_pos": 505, "annotation": "n_glycosylation_sequon" }, { "start_pos": 669, "end_pos": 671, "annotation": "n_glycosylation_sequon" }, { "start_pos": 725, "end_pos": 727, "annotation": "n_glycosylation_sequon" }, { "start_pos": 761, "end_pos": 763, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AAH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAH3" }, { "id": "PF11600", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11600" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Chromatin assembly factor 1 p150 subunit acidic region", "eco_id": "ECO_0000259", "start_pos": 317, "end_pos": 455, "start_aa": "Ala", "end_aa": "Val", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1AAH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAH3" }, { "id": "PF12253", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12253" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Chromatin assembly factor 1 subunit A dimerization", "eco_id": "ECO_0000259", "start_pos": 534, "end_pos": 606, "start_aa": "Lys", "end_aa": "Asp", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1AAH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAH3" }, { "id": "PF15539", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15539" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Chromatin assembly factor 1 subunit p150 C-terminal", "eco_id": "ECO_0000259", "start_pos": 639, "end_pos": 911, "start_aa": "Ala", "end_aa": "Val", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1AAH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAH3" }, { "id": "PF15557", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15557" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Chromatin assembly factor 1 subunit p150 N-terminal", "eco_id": "ECO_0000259", "start_pos": 2, "end_pos": 177, "start_aa": "Ala", "end_aa": "Asn", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 155, "end_pos": 157 }, { "start_pos": 204, "end_pos": 206 }, { "start_pos": 244, "end_pos": 246 }, { "start_pos": 259, "end_pos": 261 }, { "start_pos": 281, "end_pos": 283 }, { "start_pos": 503, "end_pos": 505 }, { "start_pos": 669, "end_pos": 671 }, { "start_pos": 725, "end_pos": 727 }, { "start_pos": 761, "end_pos": 763 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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"o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A7W1-1", "uniprot_ac": "A0A8V1A7W1", "uniprot_id": "A0A8V1A7W1_CHICK", "mass": { "chemical_mass": 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26091, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028184", "url": "https://www.ensembl.org/id/ENSGALG00010028184" } ] } } ], "crossref": [ { "id": "A0A8V1A7W1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A7W1", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR001129", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001129", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023352", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023352", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A7W1", "url": "https://www.orthodb.org/?gene=A0A8V1A7W1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31004", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31004", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31004:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31004:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01124", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01124", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1A7W1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7W1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A7W1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7W1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAADPTLPPEEVALLELGKAAPPDEDPPAPDDGRGDPDATLLWDQRQHGTQGQPEPTDTKRRSRPEGAHDDPEEGTPACPPPEADGEEDPGLPVMADHVFVPIDLHCIERTPAEQRKQQPTPQPQEEGRGGCAPPRDRPNSILPKQAFLPGGPSLYRGLLGFERQAAKLPAEGPRCPCAEVCSTAALKAVASVVGALFLCPCLIYGAYVFLPFDAPLLPTISTRLVYTLRCAAFATVPIVLGMIISGISRLCSAALEPFGKLQREVEIHRTYVSQSVHLFILYFFNMAVLATYLQQELLKLIPLLTGLFAISRLTYWLSYAFGRSFRAFGFAMTFLPLVAMLLWNLYSMFVLEPENLLAVATAKPEESSQQSRARLRNESVVEDVETGQHRHQPSPHAEGQQLRL", "length": 406, "header": "tr|A0A8V1A7W1-1|A0A8V1A7W1_CHICK Isoform 1 of Transmembrane protein 79 OS=Gallus gallus OX=9031 GN=TMEM79 PE=4 SV=1 CANONICAL=A0A8V1A7W1-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A7W1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7W1/entry#A0A8V1A7W1-1", "sequence": { "sequence": "MAAADPTLPPEEVALLELGKAAPPDEDPPAPDDGRGDPDATLLWDQRQHGTQGQPEPTDTKRRSRPEGAHDDPEEGTPACPPPEADGEEDPGLPVMADHVFVPIDLHCIERTPAEQRKQQPTPQPQEEGRGGCAPPRDRPNSILPKQAFLPGGPSLYRGLLGFERQAAKLPAEGPRCPCAEVCSTAALKAVASVVGALFLCPCLIYGAYVFLPFDAPLLPTISTRLVYTLRCAAFATVPIVLGMIISGISRLCSAALEPFGKLQREVEIHRTYVSQSVHLFILYFFNMAVLATYLQQELLKLIPLLTGLFAISRLTYWLSYAFGRSFRAFGFAMTFLPLVAMLLWNLYSMFVLEPENLLAVATAKPEESSQQSRARLRNESVVEDVETGQHRHQPSPHAEGQQLRL", "length": 406, "header": "tr|A0A8V1A7W1-1|A0A8V1A7W1_CHICK Isoform 1 of Transmembrane protein 79 OS=Gallus gallus OX=9031 GN=TMEM79 PE=4 SV=1 CANONICAL=A0A8V1A7W1-1" }, "locus": { "chromosome": "25", "start_pos": 28706, "end_pos": 26495, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068298.1", "url": "https://www.ensembl.org/id/ENSGALT00010068298.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042041.1", "url": "https://www.ensembl.org/id/ENSGALP00010042041.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 77, "start_aa": "Thr", "end_pos": 77, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr77", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "trans-Golgi network membrane", "id": "GO:0032588", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032588", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7W1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7W1" } ], "pmid": "" }, { "name": "lysosomal membrane", "id": "GO:0005765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005765", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7W1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7W1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7W1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7W1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "regulated exocytosis", "id": "GO:0045055", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045055", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7W1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7W1" } ], "pmid": "" }, { "name": "establishment of skin barrier", "id": "GO:0061436", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061436", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7W1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7W1" } ], "pmid": "" }, { "name": "epithelial cell maturation", "id": "GO:0002070", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002070", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7W1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7W1" } ], "pmid": "" }, { "name": "positive regulation of epidermis development", "id": "GO:0045684", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045684", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7W1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7W1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 379, "end_pos": 381, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 77 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 379, "end_pos": 381 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": 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"total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A7W3-1", "uniprot_ac": "A0A8V1A7W3", "uniprot_id": "A0A8V1A7W3_CHICK", "mass": { "chemical_mass": 135895.0, "monoisotopic_mass": 135895.0 }, "refseq": { "ac": "XP_004944563", "name": "nucleolar protein 8 isoform X4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004944563" }, "gene_names": [ { "name": "NOL8", "type": "recommended", "evidence": [ { "id": "A0A8V1A7W3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7W3" } ] }, { "name": "NOL8", "type": "synonym", "evidence": [ { "id": "XP_004944563", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004944563" } ] } ], "protein_names": [ { "name": "Nucleolar protein 8", "type": "recommended", "evidence": [ { "id": "A0A8V1A7W3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7W3/entry#names_and_taxonomy" } ] }, { "name": "nucleolar protein 8 isoform X4", "type": "synonym", "evidence": [ { "id": "XP_004944563", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004944563" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052543.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004944563.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004944563", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004944563" } ] }, { "annotation": "Plays an essential role in the survival of diffuse-type gastric cancer cells. Acts as a nucleolar anchoring protein for DDX47. May be involved in regulation of gene expression at the post-transcriptional level or in ribosome biogenesis in cancer cells.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7W3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7W3#function" }, { "database": "UniProtKB", "id": "ARBA00054821", "url": "https://www.uniprot.org/uniprotkb/ARBA00054821#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7W3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7W3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NOL8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7W3", "locus": { "chromosome": "12", "start_pos": 3659514, "end_pos": 3645102, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027207", "url": "https://www.ensembl.org/id/ENSGALG00010027207" } ] } } ], "crossref": [ { "id": "A0A8V1A7W3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A7W3", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd12226", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12226", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "415955", "url": "https://www.ncbi.nlm.nih.gov/gene/415955", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034138", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034138", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:415955", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415955", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1A7W3", "url": "https://www.orthodb.org/?gene=A0A8V1A7W3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48029", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48029", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR48029:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48029:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00076", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00076", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004944563", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004944563", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1A7W3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7W3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A7W3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7W3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": 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transduction of intracellular signals.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACY3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACY3#function" }, { "database": "UniProtKB", "id": "ARBA00059037", "url": "https://www.uniprot.org/uniprotkb/ARBA00059037#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7Z0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7Z0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CRKL", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7Z0", "locus": { "chromosome": "15", "start_pos": 8266284, "end_pos": 8281964, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010026221", "url": "https://www.ensembl.org/id/ENSGALG00010026221" } ] } } ], "crossref": [ { "id": "A0A8V1A7Z0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A7Z0", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd09926", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09926", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd11758", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11758", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd11759", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11759", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "416939", "url": "https://www.ncbi.nlm.nih.gov/gene/416939", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000980", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000980", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035457", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035457", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035458", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035458", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036028", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036028", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036860", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036860", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051184", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051184", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416939", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416939", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WYVGPLS", "url": "https://omabrowser.org/oma/group/WYVGPLS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A7Z0", "url": "https://www.orthodb.org/?gene=A0A8V1A7Z0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ACY3", "url": "https://www.orthodb.org/?gene=A0A8V1ACY3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19969", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19969", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19969:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19969:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00017", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00017", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00018", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00018", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07653", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07653", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1A7Z0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7Z0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A7Z0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7Z0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ACY3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACY3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ACY3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACY3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "ERREGCCPAHRAAEHIGALSAAPGRPRPAILGPPPQRHGASFSASPVPGPPIRRAGRFLLAPGPAACPSGPSPPRLSSRRASGLLAFFLPSLALPRPEPCPPPPGSIRRTAPAGTWARCRGRRRRRGCRGSGTACSWCGTRPPARGTTCSRCPRTPGCPTTSLTPCPTAALRSAIRSSSTCPPCWSSTRSTTWIPPPSSSPRPGEYPSPPMGSGSAPAMSAAEENVEYVRTLYDFPGNDAEDLPFKKGEILVIVEKPEEQWWSARNKDGRIGMIPVPYVEKLVRSSIGKHGNRNSNSYGIPEPAHAYAQPQTTSPLPTVSSTPGAVINPLPSTQNGPVYAKAIQKRVPCAYDKTALALEIRAHELSRIAQDVCGSNENRTRSPDCPVPNHKATLPTGLKHSLTTTAHYK", "length": 409, "header": "tr|A0A8V1A7Z0-1|A0A8V1A7Z0_CHICK Isoform 1 of CRK like proto-onco, adaptor protein OS=Gallus gallus OX=9031 GN=CRKL PE=1 SV=1 CANONICAL=A0A8V1A7Z0-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A7Z0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7Z0/entry#A0A8V1A7Z0-1", "sequence": { "sequence": "ERREGCCPAHRAAEHIGALSAAPGRPRPAILGPPPQRHGASFSASPVPGPPIRRAGRFLLAPGPAACPSGPSPPRLSSRRASGLLAFFLPSLALPRPEPCPPPPGSIRRTAPAGTWARCRGRRRRRGCRGSGTACSWCGTRPPARGTTCSRCPRTPGCPTTSLTPCPTAALRSAIRSSSTCPPCWSSTRSTTWIPPPSSSPRPGEYPSPPMGSGSAPAMSAAEENVEYVRTLYDFPGNDAEDLPFKKGEILVIVEKPEEQWWSARNKDGRIGMIPVPYVEKLVRSSIGKHGNRNSNSYGIPEPAHAYAQPQTTSPLPTVSSTPGAVINPLPSTQNGPVYAKAIQKRVPCAYDKTALALEIRAHELSRIAQDVCGSNENRTRSPDCPVPNHKATLPTGLKHSLTTTAHYK", "length": 409, "header": "tr|A0A8V1A7Z0-1|A0A8V1A7Z0_CHICK Isoform 1 of CRK like proto-onco, adaptor protein OS=Gallus gallus OX=9031 GN=CRKL PE=1 SV=1 CANONICAL=A0A8V1A7Z0-1" }, "locus": { "chromosome": "15", "start_pos": 8281795, "end_pos": 8272951, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063807.1", "url": "https://www.ensembl.org/id/ENSGALT00010063807.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039344.1", "url": "https://www.ensembl.org/id/ENSGALP00010039344.1" } ] } }, { "isoform_ac": "A0A8V1ACY3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7Z0/entry#A0A8V1ACY3-1", "sequence": { "sequence": "MSSAARFDSSDRSSWYVGPVSRAEAQTRLQGQRHGMFLVRDSSTCPGDYVLSVSENSRVSHYIINSLPNRRFKIGDQEFEHLPALLEFYKIHYLDTTTLIEPAPRYPSPPMGSGSAPAMSAAEENVEYVRTLYDFPGNDAEDLPFKKGEILVIVEKPEEQWWSARNKDGRIGMIPVPYVEKLVRSSIGKHGNRNSNSYGIPEPAHAYAQPQTTSPLPTVSSTPGAVINPLPSTQNGPVYAKAIQKRVPCAYDKTALALEVGDIVKVTRMNINGQWEGEVNGRKGLFPFTHVKIFDPQNPDENE", "length": 303, "header": "tr|A0A8V1ACY3-1|A0A8V1ACY3_CHICK Computationally mapped isoform of Crk-like protein OS=Gallus gallus OX=9031 GN=CRKL PE=1 SV=1 CANONICAL=A0A8V1A7Z0-1" }, "locus": { "chromosome": "15", "start_pos": 8281499, "end_pos": 8270064, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063811.1", "url": "https://www.ensembl.org/id/ENSGALT00010063811.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039346.1", "url": "https://www.ensembl.org/id/ENSGALP00010039346.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 168, "start_aa": "Thr", "end_pos": 168, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr168", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 322, "start_aa": "Thr", "end_pos": 322, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr322", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:416939", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416939", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1UYQ0-1", "protein_name": "Crk-like protein", "gene_name": "CRKL", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSSARFDSSDRSAWYMGPVSRQEAQTRLQGQRHGMFLVRDSSTCPGDYVLSVSENSRVSHYIINSLPNRRFKIGDQEFDHLPALLEFYKIHYLDTTTLIEPAPRYPSPPVGSVSAPNLPTAEENLEYVRTLYDFPGNDAEDLPFKKGEILVIIEKPEEQWWSARNKEGRVGMIPVPYVEKLVRSSPLGKHGNRNSNSYGIPEPAHAYAQPQTTAPLPAVPSTPGVTVNPLPSTQNGPVFAKAIQKRVPCAYDKTALALEVGDIVKVTRMNINGQWEGEVNGRKGLFPFTHVKIIDPQNPDENE", "length": 303 }, "evidence": [ { "id": "A0A8V1A7Z0", "url": "https://omabrowser.org/oma/group/A0A8V1A7Z0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0AAA9RVE1-1", "protein_name": "Crk-like protein", "gene_name": "CRKL", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSSARFDSSDRSAWYMGPVSRQEAQTRLQGQRHGVFLVRDSSTCPGDYVLSVSENSRVSHYIINSLPNRRFKIGDQEFDHLPALLEFYKIHYLDTTTLIEPAPRYPSPPVGSVSAPSLPAAEETLEYVRTLYDFPGNDAEDLPFKKGEILVIVEKPEEQWWSARNKDGRVGMIPVPYVEKLVRASAQGKPGNRNSSSYGVPEPAHAYAQPQTTAPPPAAGAPGAAVSPLPSTQNGPVFAKAIQKRVPCAYDKTALALEVGDIVKVTRMNINGQWEGEVNGRKGLFPFTHVKIIDPQNPDESE", "length": 302 }, "evidence": [ { "id": "A0A8V1A7Z0", "url": "https://omabrowser.org/oma/group/A0A8V1A7Z0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3HFZ9-1", "protein_name": "Crk-like protein", "gene_name": "Crkl", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSSARFDSADRSAWYMGPVSRQEAQTRLQGQRHGMFLVRDSSTCPGDYVLSVSENSRVSHYIINSLPNRRFKIGDQEFDHLPALLEFYKIHYLDTTTLIEPAPRYPSPPMGSVSAPNLSAAEENVEYVRTLYDFPGNDAEDLPFKKGEILVIIEKPEEQWWSARNKDGRVGMIPVPYVEKLVRSSPHGKHGNRNSNSYGIPEPAHAYAQPQTTTPLPTVASTPGASINPLPSTQNGPVFAKAIQKRVPCAYDKTALALEVGDIVKVTRMNINGQWEGEVNGRKGLFPFTHVKIFDPQNPDDNE", "length": 303 }, "evidence": [ { "id": "A0A8V1A7Z0", "url": "https://omabrowser.org/oma/group/A0A8V1A7Z0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P46109-1", "protein_name": "Crk-like protein", "gene_name": "CRKL", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSSARFDSSDRSAWYMGPVSRQEAQTRLQGQRHGMFLVRDSSTCPGDYVLSVSENSRVSHYIINSLPNRRFKIGDQEFDHLPALLEFYKIHYLDTTTLIEPAPRYPSPPMGSVSAPNLPTAEDNLEYVRTLYDFPGNDAEDLPFKKGEILVIIEKPEEQWWSARNKDGRVGMIPVPYVEKLVRSSPHGKHGNRNSNSYGIPEPAHAYAQPQTTTPLPAVSGSPGAAITPLPSTQNGPVFAKAIQKRVPCAYDKTALALEVGDIVKVTRMNINGQWEGEVNGRKGLFPFTHVKIFDPQNPDENE", "length": 303 }, "evidence": [ { "id": "A0A8V1A7Z0", "url": "https://omabrowser.org/oma/group/A0A8V1A7Z0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P47941-1", "protein_name": "Crk-like protein", "gene_name": "Crkl", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSARFDSSDRSAWYMGPVTRQEAQTRLQGQRHGMFLVRDSSTCPGDYVLSVSENSRVSHYIINSLPNRRFKIGDQEFDHLPALLEFYKIHYLDTTTLIEPAPRYPSPPVGSVSAPNLPTAEENLEYVRTLYDFPGNDAEDLPFKKGELLVIIEKPEEQWWSARNKDGRVGMIPVPYVEKLVRSSPHGKHGNRNSNSYGIPEPAHAYAQPQTTTPLPTVASTPGAAINPLPSTQNGPVFAKAIQKRVPCAYDKTALALEVGDIVKVTRMNINGQWEGEVNGRKGLFPFTHVKIFDPQNPDDNE", "length": 303 }, "evidence": [ { "id": "A0A8V1A7Z0", "url": "https://omabrowser.org/oma/group/A0A8V1A7Z0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5U2U2-1", "protein_name": "Crk-like protein", "gene_name": "Crkl", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSARFDSSDRSAWYMGPVSRQEAQTRLQGQRHGMFLVRDSSTCPGDYVLSVSENSRVSHYIINSLPNRRFKIGDQEFDHLPALLEFYKIHYLDTTTLIEPAPRYPNPPMGSVSAPNLSTAEENLEYVRTLYDFPGNDAEDLPFKKGELLVIIEKPEEQWWSARNKDGRVGMIPVPYVEKLVRSSPHGKHGNRNSNSYGIPEPAHAYAQPQTTTPLPTVASTPGAAINPLPSTQNGPVFAKAIQKRVPCAYDKTALALEVGDIVKVTRMNINGQWEGEVNGRKGLFPFTHVKIFDPQNPDDNE", "length": 303 }, "evidence": [ { "id": "A0A8V1A7Z0", "url": "https://omabrowser.org/oma/group/A0A8V1A7Z0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "phosphotyrosine residue binding", "id": "GO:0001784", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001784", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7Z0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7Z0" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7Z0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7Z0" } ], "pmid": "" }, { "name": "RNA polymerase II-specific DNA-binding transcription factor binding", "id": "GO:0061629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061629", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7Z0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7Z0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7Z0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7Z0" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7Z0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7Z0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 12, "go_terms": [ { "name": "positive regulation of cell population proliferation", "id": "GO:0008284", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008284", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7Z0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7Z0" } ], "pmid": "" }, { "name": "negative regulation of gene expression", "id": "GO:0010629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010629", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7Z0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7Z0" } ], "pmid": "" }, { "name": "positive regulation of ERK1 and ERK2 cascade", "id": "GO:0070374", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070374", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7Z0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7Z0" } ], "pmid": "" }, { "name": "positive regulation of substrate adhesion-dependent cell spreading", "id": "GO:1900026", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900026", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7Z0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7Z0" } ], "pmid": "" }, { "name": "cellular response to transforming growth factor beta stimulus", "id": "GO:0071560", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071560", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7Z0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7Z0" } ], "pmid": "" }, { "name": "negative regulation of SMAD protein signal transduction", "id": "GO:0060392", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060392", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7Z0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7Z0" } ], "pmid": "" }, { "name": "positive regulation of glial cell migration", "id": "GO:1903977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903977", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7Z0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7Z0" } ], "pmid": "" }, { "name": "regulation of cell adhesion", "id": "GO:0030155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030155", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7Z0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7Z0" } ], "pmid": "" }, { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7Z0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7Z0" } ], "pmid": "" }, { "name": "cellular response to growth factor stimulus", "id": "GO:0071363", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071363", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7Z0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7Z0" } ], "pmid": "" }, { "name": "regulation of cell migration", "id": "GO:0030334", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030334", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7Z0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7Z0" } ], "pmid": "" }, { "name": "regulation of gene expression", "id": "GO:0010468", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010468", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7Z0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7Z0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 378, "end_pos": 380, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1A7Z0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7Z0" }, { "id": "PS50002", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50002" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SH3", "eco_id": "ECO_0000259", "start_pos": 224, "end_pos": 284, "start_aa": "Glu", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 168, 322 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 378, "end_pos": 380 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", 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"count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": 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"uniprot_ac": "A0A8V1A818", "uniprot_id": "A0A8V1A818_CHICK", "mass": { "chemical_mass": 99073.0, "monoisotopic_mass": 99073.0 }, "refseq": { "ac": "XP_015148406", "name": "putative RNA-binding protein 15B", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015148406" }, "gene_names": [ { "name": "RBM15B", "type": "recommended", "evidence": [ { "id": "A0A8V1A818", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A818" } ] }, { "name": "RBM15B", "type": "synonym", "evidence": [ { "id": "XP_015148406", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015148406" } ] } ], "protein_names": [ { "name": "Putative RNA-binding protein 15B", "type": "recommended", "evidence": [ { "id": "A0A8V1A818", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A818/entry#names_and_taxonomy" } ] }, { "name": "RNA-binding motif protein 15B", "type": "synonym", "evidence": [ { "id": "A0A8V1A818", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A818/entry#names_and_taxonomy" } ] }, { "name": "putative RNA-binding protein 15B", "type": "synonym", "evidence": [ { "id": "XP_015148406", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015148406" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052543.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015148406.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015148406", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015148406" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A818", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A818" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RBM15B", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A818", "locus": { "chromosome": "12", "start_pos": 2330123, "end_pos": 2325058, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028206", "url": "https://www.ensembl.org/id/ENSGALG00010028206" } ] } } ], "crossref": [ { "id": "A0A8V1A818", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A818", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd12556", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12556", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12558", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12558", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd21550", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21550", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "770664", "url": "https://www.ncbi.nlm.nih.gov/gene/770664", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010912", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010912", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012921", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012921", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016194", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016194", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034535", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034535", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034536", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034536", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:770664", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:770664", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GLFRQFQ", "url": "https://omabrowser.org/oma/group/GLFRQFQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A818", "url": "https://www.orthodb.org/?gene=A0A8V1A818", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23189", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23189", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00076", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00076", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07744", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07744", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015148406", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015148406", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1A818", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A818", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A818-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A818-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKRGSERDASPPGAGGGRAAAAKRPRERERESSSRRGPHRSSGASRSSRDKSTPGGGGGGGGGGGGSGGSGGGGSGSRSHRGDERAGGADSNHRPAASGSASGARGQAAPSSSSSSSSSSRALGVPKAKALPGAVVAPSLLLAGPPPGAAPSLLLAPLGGSAGLAGEPPGSCEYKTLLVSGLSAALPDQLLEDGLFRLFQRFAGGGAGDISVKLSHTPELGRVAYVNFRHPGDARDARRHARARQLLLYDRPLKVEPVYLRGGRRSRTPPPAPSPEPLGYLPPLHGAYQYKQRSLSPVTSPLLREPRPRHAHAAAAAFALEAAAIGLSRERERALDYYGLYDERGRPYSYPIVAEEDLMPEDDQRATRNLFIGNLDHNVSEVELRRAFEKYGIIEEVVIKRPARGQGGAYAFLKFQNLDMAHRAKVAMSGRVVGRNPIKIGYGKANPTTRLWVGGLGPSTSLAALAREFDRFGSIRTIDYVKGDSFAYIQYESLDAAQAACAQMRGFPLGGPERRLRVDFAKAEETRYPQQYQPAPLPVHYELLADGYSRHRSLEQDLRVRDRTPPHLLYSDRDRSFAEADWASPAKNAERRNNLEGYSRSVRSRSGERWASDSDRAVPKLWEERRKRRSLSSDRGRTAHSPYEDRSRTKASGPALDRSPERARKENHTTESGTEKEQSNSLQNNRHATEEKPHREASDAPQPKKRDSERNHRTGESESKAHEEPKSETKKLKNLSEYAQTLQLAWNGLLVLKNSCFPTSMHILEGDLGVINGLLKDHSSGGKLTQLKIAQRLRLDQPKLDEVTRRIKQGSPNGYAVLLATQSAPGGAGAEGTFPVVEPGLQRRLLRNLVSYLKQKQAAGVISLPVGGAKGRDSTGMLYAFPPCEFSQQYLQSALRTLGKLEEEHMVIVIVKDTA", "length": 915, "header": "tr|A0A8V1A818-1|A0A8V1A818_CHICK Isoform 1 of Putative RNA-binding protein 15B OS=Gallus gallus OX=9031 GN=RBM15B PE=1 SV=1 CANONICAL=A0A8V1A818-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A818-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A818/entry#A0A8V1A818-1", "sequence": { "sequence": "MKRGSERDASPPGAGGGRAAAAKRPRERERESSSRRGPHRSSGASRSSRDKSTPGGGGGGGGGGGGSGGSGGGGSGSRSHRGDERAGGADSNHRPAASGSASGARGQAAPSSSSSSSSSSRALGVPKAKALPGAVVAPSLLLAGPPPGAAPSLLLAPLGGSAGLAGEPPGSCEYKTLLVSGLSAALPDQLLEDGLFRLFQRFAGGGAGDISVKLSHTPELGRVAYVNFRHPGDARDARRHARARQLLLYDRPLKVEPVYLRGGRRSRTPPPAPSPEPLGYLPPLHGAYQYKQRSLSPVTSPLLREPRPRHAHAAAAAFALEAAAIGLSRERERALDYYGLYDERGRPYSYPIVAEEDLMPEDDQRATRNLFIGNLDHNVSEVELRRAFEKYGIIEEVVIKRPARGQGGAYAFLKFQNLDMAHRAKVAMSGRVVGRNPIKIGYGKANPTTRLWVGGLGPSTSLAALAREFDRFGSIRTIDYVKGDSFAYIQYESLDAAQAACAQMRGFPLGGPERRLRVDFAKAEETRYPQQYQPAPLPVHYELLADGYSRHRSLEQDLRVRDRTPPHLLYSDRDRSFAEADWASPAKNAERRNNLEGYSRSVRSRSGERWASDSDRAVPKLWEERRKRRSLSSDRGRTAHSPYEDRSRTKASGPALDRSPERARKENHTTESGTEKEQSNSLQNNRHATEEKPHREASDAPQPKKRDSERNHRTGESESKAHEEPKSETKKLKNLSEYAQTLQLAWNGLLVLKNSCFPTSMHILEGDLGVINGLLKDHSSGGKLTQLKIAQRLRLDQPKLDEVTRRIKQGSPNGYAVLLATQSAPGGAGAEGTFPVVEPGLQRRLLRNLVSYLKQKQAAGVISLPVGGAKGRDSTGMLYAFPPCEFSQQYLQSALRTLGKLEEEHMVIVIVKDTA", "length": 915, "header": "tr|A0A8V1A818-1|A0A8V1A818_CHICK Isoform 1 of Putative RNA-binding protein 15B OS=Gallus gallus OX=9031 GN=RBM15B PE=1 SV=1 CANONICAL=A0A8V1A818-1" }, "locus": { "chromosome": "12", "start_pos": 2327862, "end_pos": 2325118, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068354.1", "url": "https://www.ensembl.org/id/ENSGALT00010068354.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042097.1", "url": "https://www.ensembl.org/id/ENSGALP00010042097.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:770664", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:770664", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZHD6-1", "protein_name": "Putative RNA-binding protein 15B", "gene_name": "Rbm15b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKRQNERDSSPSGRGSSSSAKRPREREREAEAGGRRAAHKASGGTKHPVPARARDKPRGSGGGGGHRDGRAAGDANHRASSGRSSGAPGGGGRTGKASGDPGAGGASPRASPLPPPPPPPGAEPAGPGTTAAPEYKTLLISSLSPALPAEHLEDRLFHQFKRFGEISLRLSHTPELGRVAYVNFRHPQDAREARQHALARQLLLYDRPLKVEPVYLRGGGSSRRSSSSSAAASTPPPGPPTPADPLGYLPLHGGYQYKQRSLSPVAAPPLREPRARHAAAAFALDAAAAAAVGLSRERALDYYGLYDDRGRPYSYQAVCEEDLMPEDDQRATRNLFIGNLDHSVSEVELRRAFEKYGIIEEVVIKRPARGQGGAYAFLKFQNLDMAHRAKVAMSGRVIGRNPIKIGYGKANPTTRLWVGGLGPNTSLAALAREFDRFGSIRTIDHVKGDSFAYIQYESLDAAQAACAKMRGFPLGGPDRRLRVDFAKAEETRYPQQYQPSPLPVHYELLTDGYTRHRNLDADLRVRDRTPPHLLYSDRDRTFLEGDWTSLSKSSDRRNSLEGYSRSVRSRSGERWGADGDRSIAKPWEERRKRRSLSSDRGRTTHSPYEERSRTKGGGQQSERGSDRTPERSRKENHSSEGTKESGSNSLSNSRHSAEERSHHHHHHEAPDSSHGKKTRESERNHRTTEAEPKTLEEPKHETKKLKTLSEYAQTLQLGWNGLLVLKNSCFPTSMHILEGDQGVISGLLKDHTSGSKLTQLKIAQRLRLDQPKLDEVTRRIKQGSPNGYAVLLAIQSTPSGPGAEGMPMVEPGLQRRLLRNLVSYLKQKQAAGVISLPVGGSKGRDSTGMLYAFPPCDFSQQYLQSALRTLGKLEEEHMVIVIVRDAA", "length": 887 }, "evidence": [ { "id": "A0A8V1A818", "url": "https://omabrowser.org/oma/group/A0A8V1A818/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1SIZ8-1", "protein_name": "Putative RNA-binding protein 15B", "gene_name": "RBM15B", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MKRQSERDSSPGGRGSSSSAKRPREREREAEAGGRRAAHKASGGTKHPVPTRAREKPRGSGGGGGGHRDGRGAGDANHRASSGRASGSGAGGGGRGGKASGDPGASGASPRASPLPPPPPPPGSEPAGPGSSAAAPEYKTLLISSLSPALPAEHLEDRLFHQFKRFGEISLRLSHTPELGRVAYVNFRHPQDAREARQHALARQLLLYDRPLKVEPVYLRGGGGGGGSSRRSSSSSAAASTPPPGPPAPADPLGYLPLHGGYQYKQRSLSPVAAPPLREPRARHAAAAFALDAAAAAAVGLSRERALDYYGLYDDRGRPYGYPAVCEEDLMPEDDQRATRNLFIGNLDHSVSEVELRRAFEKYGIIEEVVIKRPARGQGGAYAFLKFQNLDMAHRAKVAMSGRVIGRNPIKIGYGKANPTTRLWVGGLGPNTSLAALAREFDRFGSIRTIDHVKGDSFAYIQYESLDAAQAACAKMRGFPLGGPDRRLRVDFAKAEETRYPQQYQPSPLPVHYELLPDGYTRHRNLDADLRVRDRTPPHLLYSDRDRTFLEGDWTSPSKSSDRRNSLEGYSRSVRSRSGERWGGDGDRGLPKPWEERRKRRSLSSDRGRTTHSPYEERSRTKGGGQQADRGSDRTPERSRKENHSSEGTKELSGNSLSNSRHGAEERSHHHHHEAPDSSHGKKTRESERNHRTTEAETKPLEEPKHETKKLKNLSEYAQTLQLGWNGLLVLKNSCFPTSMHILEGDQGVISGLLKDHTSGSKLTQLKIAQRLRLDQPKLDEVTRRIKQGSPNGYAVLLATQATPSGPGTEGMPTVEPGLQRRLLRNLVSYLKQKQAAGVISLPVGGSKGRDSTGMLYAFPPCDFSQQYLQSALRTLGKLEEEHMVIVIVRDTA", "length": 893 }, "evidence": [ { "id": "A0A8V1A818", "url": "https://omabrowser.org/oma/group/A0A8V1A818/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F6RM04-1", "protein_name": "Putative RNA-binding protein 15B", "gene_name": "RBM15B", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MKRQSERDSSPSGRGSSSSAKRPREREREAEAGGRRAAHKASGGAKHPVPTRARDKPRGSGGSGGGHRDGRGAGDANHRASSGRSSGSGAGGGGRGGKASGDPGASGASPRASPLPPPPPPPGAEPTGPGSSAAAPEYKTLLISSLSPALPAEHLEDRLFHQFKRFGEISLRLSHTPELGRVAYVNFRHPQDAREARQHALARQLLLYDRPLKVEPVYLRGGGGGGGSSRRSSSSSAAASTPPPGPPAPADPLGYLPLHGGYQYKQRSLSPVAAPPLREPRARHAAAAFALDAAAAAAAVGLSRERALDYYGLYDDRGRPYGYPAVCEEDLMPEDDQRATRNLFIGNLDHSVSEVELRRAFEKYGIIEEVVIKRPARGQGGAYAFLKFQNLDMAHRAKVGMSGRVIGRNPIKIGYGKANPTTRLWVGGLGPNTSLAALAREFDRFGSIRTIDHVKGDSFAYIQYESLDAAQAACAKMRGFPLGGPDRRLRVDFAKAEETRYPQQYQPSPLPVHYELLPDGYTRHRNLDADLRVRDRTPPHLLYSDRERTFLEGDWTSPSKSSDRRNSLEGYSRSVRSRSGERWGGDGDRGLPKAWEDRRKRRSLSSDRGRATHSPYEERSRTKGGGQPADRGSDRTPERSRKENHSSEGTKESGSNSLSNSRHGAEERSHHHHHEAPDSSHGKKTRESERNHRTTEAEPKPLEEPKHETKKLKNLSEYAQTLQLGWNGLLVLKNSCFPTSMHILEGDQGVISSLLKDHTSGSKLTQLKIAQRLRLDQPKLDEVTRRIKQGSPNGYAVLLATQATPSGPGSEGMPTVEPGLQRRLLRNLVSYLKQKQAAGVISLPVGGSKGRDSTGMLYAFPPCDFSQQYLQSALRTLGKLEEEHMVIVIVRDTA", "length": 894 }, "evidence": [ { "id": "A0A8V1A818", "url": "https://omabrowser.org/oma/group/A0A8V1A818/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q6PHZ5-1", "protein_name": "Putative RNA-binding protein 15B", "gene_name": "Rbm15b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKRQSERDSSPSGRGSSSSAKRPREREREAEAGGRRAAHKASGGTKHPVPARARDKPRGSGGGGGHRDGRAAGDANHRASGGRSSGAPGGGGRTGKASGDPGAGGASPRASPLPPPPPPPGAEPAGPGSTAAPEYKTLLISSLSPALPAEHLEDRLFHQFKRFGEISLRLSHTPELGRVAYVNFRHPQDAREARQHALARQLLLYDRPLKVEPVYLRGGGSSRRSSSSSAAASTPPPGPPAPADPLGYLPLHGGYQYKQRSLSPVAAPPLREPRARHAAAAFALDAAAAAAVGLSRERALDYYGLYDDRGRPYGYQAVCEEDLMPEDDQRATRNLFIGNLDHSVSEVELRRAFEKYGIIEEVVIKRPARGQGGAYAFLKFQNLDMAHRAKVAMSGRVIGRNPIKIGYGKANPTTRLWVGGLGPNTSLAALAREFDRFGSIRTIDHVKGDSFAYIQYESLDAAQAACAKMRGFPLGGPDRRLRVDFAKAEETRYPQQYQPSPLPVHYELLTDGYTRHRNLDADLRVRDRTPPHLLYSDRDRTFLEGDWTSLSKSSDRRNSLEGYSRSVRSRSGERWGGDGDRSIAKPWEERRKRRSLSSDRGRTTHSPYEERSRTKGGGQQSERGSDRTPERSRKENHSSEGTKESGSNSLSNSRHGAEERSHHHHHHEAPDSSHGKKTRESERNHRTTEAEPKTLEEPKHETKKLKTLSEYAQTLQLGWNGLLVLKNSCFPTSMHILEGDQGVISGLLKDHPSGSKLTQLKIAQRLRLDQPKLDEVTRRIKQGSPNGYAVLLAIQSTPSGPGAEGMPVVEPGLQRRLLRNLVSYLKQKQAAGVISLPVGGSKGRDNTGMLYAFPPCDFSQQYLQSALRTLGKLEEEHMVIVIVRDTA", "length": 887 }, "evidence": [ { "id": "A0A8V1A818", "url": "https://omabrowser.org/oma/group/A0A8V1A818/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8NDT2-1", "protein_name": "Putative RNA-binding protein 15B", "gene_name": "RBM15B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKRQSERDSSPSGRGSSSSAKRPREREREAEAGGRRAAHKASGGAKHPVPARARDKPRGSGSGGGGHRDGRGTGDANHRASSGRSSGSGAGGGGRGGKASGDPGASGMSPRASPLPPPPPPPGAEPACPGSSAAAPEYKTLLISSLSPALPAEHLEDRLFHQFKRFGEISLRLSHTPELGRVAYVNFRHPQDAREARQHALARQLLLYDRPLKVEPVYLRGGGGSSRRSSSSSAAASTPPPGPPAPADPLGYLPLHGGYQYKQRSLSPVAAPPLREPRARHAAAAFALDAAAAAAVGLSRERALDYYGLYDDRGRPYGYPAVCEEDLMPEDDQRATRNLFIGNLDHSVSEVELRRAFEKYGIIEEVVIKRPARGQGGAYAFLKFQNLDMAHRAKVAMSGRVIGRNPIKIGYGKANPTTRLWVGGLGPNTSLAALAREFDRFGSIRTIDHVKGDSFAYIQYESLDAAQAACAKMRGFPLGGPDRRLRVDFAKAEETRYPQQYQPSPLPVHYELLTDGYTRHRNLDADLVRDRTPPHLLYSDRDRTFLEGDWTSPSKSSDRRNSLEGYSRSVRSRSGERWGADGDRGLPKPWEERRKRRSLSSDRGRTTHSPYEERSRTKGSGQQSERGSDRTPERSRKENHSSEGTKESSSNSLSNSRHGAEERGHHHHHHEAADSSHGKKARDSERNHRTTEAEPKPLEEPKHETKKLKNLSEYAQTLQLGWNGLLVLKNSCFPTSMHILEGDQGVISSLLKDHTSGSKLTQLKIAQRLRLDQPKLDEVTRRIKQGSPNGYAVLLATQATPSGLGTEGMPTVEPGLQRRLLRNLVSYLKQKQAAGVISLPVGGSKGRDGTGMLYAFPPCDFSQQYLQSALRTLGKLEEEHMVIVIVRDTA", "length": 890 }, "evidence": [ { "id": "A0A8V1A818", "url": "https://omabrowser.org/oma/group/A0A8V1A818/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "RNA N6-methyladenosine methyltransferase complex", "id": "GO:0036396", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036396", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A818", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A818" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A818", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A818" } ], "pmid": "" }, { "name": "nuclear envelope", "id": "GO:0005635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005635", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A818", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A818" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A818", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A818" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A818", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A818" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A818", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A818" } ], "pmid": "" }, { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A818", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A818" } ], "pmid": "" }, { "name": "mRNA export from nucleus", "id": "GO:0006406", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006406", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A818", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A818" } ], "pmid": "" }, { "name": "RNA splicing", "id": "GO:0008380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008380", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A818", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A818" } ], "pmid": "" }, { "name": "RNA methylation", "id": "GO:0001510", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001510", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A818", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A818" } ], "pmid": "" }, { "name": "regulation of alternative mRNA splicing, via spliceosome", "id": "GO:0000381", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000381", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A818", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A818" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 378, "end_pos": 380, "annotation": "n_glycosylation_sequon" }, { "start_pos": 667, "end_pos": 669, "annotation": "n_glycosylation_sequon" }, { "start_pos": 734, "end_pos": 736, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1A818", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A818" }, { "id": "PS50102", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50102" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RRM", "eco_id": "ECO_0000259", "start_pos": 175, "end_pos": 256, "start_aa": "Lys", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1A818", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A818" }, { "id": "PS50917", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50917" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SPOC", "eco_id": "ECO_0000259", "start_pos": 735, "end_pos": 914, "start_aa": "Leu", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 378, "end_pos": 380 }, { "start_pos": 667, "end_pos": 669 }, { "start_pos": 734, "end_pos": 736 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A821-1", "uniprot_ac": "A0A8V1A821", "uniprot_id": "A0A8V1A821_CHICK", "mass": { "chemical_mass": 43767.0, "monoisotopic_mass": 43767.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "AIG1-type G domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8V1A821", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A821/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A821", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A821" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A821", "locus": {} } ], "crossref": [ { "id": "A0A8V1A821", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A821", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR006703", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006703", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045058", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045058", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR10903", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10903", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10903:SF73", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10903:SF73", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04548", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04548", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1A821", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A821", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A821-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A821-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MADRAAETGAAAPPRDCASSECPAEAVGTERRGTEREEDGEEEKPGAGGPDGSEPKRRESGARAESAEKGHESGDGACGSTAEKRGEPRDGAPVGGGEPQELRILLLGRSGGGRSATGNTLLCREEFKSQLASQPVTTTCKEGRRDWGEWCVVVMDTPAIFGGSQWDKKQLEEERRHCVHFGTHKYCVLLLVTQLGRYTREDREVQKRVKQVFGKGAKKRMVVVFTRREDLGDSSLDEFVKTAENGALRKLVKEGNPPMGTVPGGRGGARWDGDIGTGRGVPAASVPHFSLPVRRLGLPGDCSVRPWRSPKKGKERHNHGRSTCPCAAQPRQRLRNAAAPGWEDWRGAKRHGEHHPGATSLRVQAVHHAGDPQLRDSSWALGWRGHRGDRHGRHLPFVGRQQ", "length": 402, "header": "tr|A0A8V1A821-1|A0A8V1A821_CHICK Isoform 1 of AIG1-type G domain-containing protein OS=Gallus gallus OX=9031 GN= PE=1 SV=1 CANONICAL=A0A8V1A821-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A821-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A821/entry#A0A8V1A821-1", "sequence": { "sequence": "MADRAAETGAAAPPRDCASSECPAEAVGTERRGTEREEDGEEEKPGAGGPDGSEPKRRESGARAESAEKGHESGDGACGSTAEKRGEPRDGAPVGGGEPQELRILLLGRSGGGRSATGNTLLCREEFKSQLASQPVTTTCKEGRRDWGEWCVVVMDTPAIFGGSQWDKKQLEEERRHCVHFGTHKYCVLLLVTQLGRYTREDREVQKRVKQVFGKGAKKRMVVVFTRREDLGDSSLDEFVKTAENGALRKLVKEGNPPMGTVPGGRGGARWDGDIGTGRGVPAASVPHFSLPVRRLGLPGDCSVRPWRSPKKGKERHNHGRSTCPCAAQPRQRLRNAAAPGWEDWRGAKRHGEHHPGATSLRVQAVHHAGDPQLRDSSWALGWRGHRGDRHGRHLPFVGRQQ", "length": 402, "header": "tr|A0A8V1A821-1|A0A8V1A821_CHICK Isoform 1 of AIG1-type G domain-containing protein OS=Gallus gallus OX=9031 GN= PE=1 SV=1 CANONICAL=A0A8V1A821-1" }, "locus": { "chromosome": "2", "start_pos": 502372, "end_pos": 495047, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066029.1", "url": "https://www.ensembl.org/id/ENSGALT00010066029.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040295.1", "url": "https://www.ensembl.org/id/ENSGALP00010040295.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A821", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A821" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A821", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A821" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1A821", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A821" }, { "id": "PS51720", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51720" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "AIG1-type G", "eco_id": "ECO_0000259", "start_pos": 99, "end_pos": 316, "start_aa": "Pro", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A837-1", "uniprot_ac": "A0A8V1A837", "uniprot_id": "A0A8V1A837_CHICK", "mass": { "chemical_mass": 39848.0, "monoisotopic_mass": 39848.0 }, "refseq": { "ac": "NP_001376377", "name": "leucine-rich repeat-containing protein 58", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376377" }, "gene_names": [ { "name": "LRRC58", "type": "recommended", "evidence": [ { "id": "A0A8V1A837", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A837" } ] }, { "name": "LRRC58", "type": "synonym", "evidence": [ { "id": "NP_001376377", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376377" } ] } ], "protein_names": [ { "name": "Leucine rich repeat containing 58", "type": "synonym", "evidence": [ { "id": "A0A8V1A837", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A837/entry#names_and_taxonomy" } ] }, { "name": "leucine-rich repeat-containing protein 58", "type": "synonym", "evidence": [ { "id": "NP_001376377", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376377" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR12888496.320634.1, SRR12888486.98249.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000017.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001376377", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376377" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A837", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A837" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LRRC58", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A837", "locus": { "chromosome": "1", "start_pos": 79982054, "end_pos": 79966933, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010026272", "url": "https://www.ensembl.org/id/ENSGALG00010026272" } ] } } ], "crossref": [ { "id": "A0A8V1A837", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A837", "database": "AlphaFoldDB", "categories": [] }, { "id": "418332", "url": "https://www.ncbi.nlm.nih.gov/gene/418332", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003591", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003591", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050216", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050216", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055414", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055414", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "GLSQWFP", "url": "https://omabrowser.org/oma/group/GLSQWFP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A837", "url": "https://www.orthodb.org/?gene=A0A8V1A837", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48051", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48051", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR48051:SF53", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48051:SF53", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF23598", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23598", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001376377", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376377", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1A837", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A837", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A837-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A837-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAAGGAAAEPEPEPPRRGPTEGEEAAAAELAAELAARRSAEARRLVLSPRRLWGPLPAGLSQWFPALEVLDVSGTGLAELGEELLALPRLHTLLAKNNRLGGPGSLPKALGQAPLSRSLRVLNLSGNRFAELPPALLGLRGLQSLSLGGNRLHGIPPDIQELRSLEFLYLGGNFITSIPPELANLPSLSSLVLCDNKIQSIPPQLAQLHSLRSLSLHNNLLTYLPREILNLVHLEELSLRGNPLVVRFVRDLTYNPPSLQELAGRTIKTRNVPYAPSDLPENLVRYLSLASNCPNPKCGGVYFDSCVRQIKFVDFCGKYRIPLMHYLCSPECSSPCSSASQSSTSQSESDSEDEASVAARRMQKVLLG", "length": 369, "header": "tr|A0A8V1A837-1|A0A8V1A837_CHICK Isoform 1 of Leucine rich repeat containing 58 OS=Gallus gallus OX=9031 GN=LRRC58 PE=4 SV=1 CANONICAL=A0A8V1A837-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A837-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A837/entry#A0A8V1A837-1", "sequence": { "sequence": "MAAAGGAAAEPEPEPPRRGPTEGEEAAAAELAAELAARRSAEARRLVLSPRRLWGPLPAGLSQWFPALEVLDVSGTGLAELGEELLALPRLHTLLAKNNRLGGPGSLPKALGQAPLSRSLRVLNLSGNRFAELPPALLGLRGLQSLSLGGNRLHGIPPDIQELRSLEFLYLGGNFITSIPPELANLPSLSSLVLCDNKIQSIPPQLAQLHSLRSLSLHNNLLTYLPREILNLVHLEELSLRGNPLVVRFVRDLTYNPPSLQELAGRTIKTRNVPYAPSDLPENLVRYLSLASNCPNPKCGGVYFDSCVRQIKFVDFCGKYRIPLMHYLCSPECSSPCSSASQSSTSQSESDSEDEASVAARRMQKVLLG", "length": 369, "header": "tr|A0A8V1A837-1|A0A8V1A837_CHICK Isoform 1 of Leucine rich repeat containing 58 OS=Gallus gallus OX=9031 GN=LRRC58 PE=4 SV=1 CANONICAL=A0A8V1A837-1" }, "locus": { "chromosome": "1", "start_pos": 79978003, "end_pos": 79966989, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063935.1", "url": "https://www.ensembl.org/id/ENSGALT00010063935.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039390.1", "url": "https://www.ensembl.org/id/ENSGALP00010039390.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 21, "start_aa": "Thr", "end_pos": 21, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr21", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0ABK0LTN7-1", "protein_name": "Leucine rich repeat containing 58", "gene_name": "Lrrc58", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEEAALGEAELNWSRLSVSAEALESELEARAEERRGSREALLRLLLPYNRLTSLPRALGSGFPHLQLLDVSGNALTALGPELLTLSGLRTLLARNNRLGGPGSLPKGLGQSPLCRSLQVLNLSGNCFQELPASLLELRALQTLSLGGNQLQSIPAEIENLQSLECLYLGGNFIKEIPPELANLPSLNYLVLCDNKIQSVPPQLSQLHSLRSLSLHNNLLTYLPREILNLIHLEELSLRGNPLVVRFVRDLTYDPPTLLELAARTIKIRSISYTPYDLPGNLLRYLGSASNCPNPKCGGVYFDCCVRQIKFVDFCGKYRLPLMHYLCSPECSSPCSSASHSSTSQSESDSEDEASVAAHRMQKVLLG", "length": 366 }, "evidence": [ { "id": "A0A8V1A837", "url": "https://omabrowser.org/oma/group/A0A8V1A837/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1MTP8-1", "protein_name": "Leucine rich repeat containing 58", "gene_name": "LRRC58", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MEEVGGAVATAGEAELNLSRLSVSLETLESELEARGEERRGAREALLRLLLPHNRLVSLPRALGSGFPHLQLLDVSGNALTALGPELLALRGLRTLLAKNNRLGGPGAFPKGLAQSPLCRSLQVLNLSGNCFQEVPTSLLELRALQTLSLGGNQLQSIPAEIENLRSLECLYLGGNFIKEIPPELGNLPSLNYLVLCDNKIQSVPPQLSQLHSLRSLSLHNNLLTYLPREILNLIHLEELSLRGNPLVVRFVRDLTYDPPTLLELAARTIKIRNISYTPYDLPGNLLRYLSLASNCPNPKCGGVYFDCCVRQIKFVDFCGKYRLPLMHYLCSPECSSPCSSASHSSTSQSESDSEDEASVAAHRMQKVLLG", "length": 371 }, "evidence": [ { "id": "A0A8V1A837", "url": "https://omabrowser.org/oma/group/A0A8V1A837/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q3UGP9-1", "protein_name": "Leucine-rich repeat-containing protein 58", "gene_name": "Lrrc58", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEEAALGEAELNWSRLSVSAEALESELEARAEERRGAREALLRLLLPYNRLTSLPRALGGGFPHLQLLDVSGNSLTALGPELLTLSGLRTLLARNNRLGGPGSLPKGLAQSPLCRSLQVLNLSGNCFQELPASLLELRALQTLSLGGNQLQSIPAEIENLRSLECLYLGGNFIKEIPPELANLPSLNYLVLCDNKIQSVPPQLSQLHSLRSLSLHNNLLTYLPREILNLIHLEELSLRGNPLVVRFVRDLTYDPPTLLELAARTIKIRSISYTPYDLPGNLLRYLGSASNCPNPKCGGVYFDCCVRQIKFVDFCGKYRLPLMHYLCSPECSSPCSSASHSSTSQSESDSEDEASVAAHRMQKVLLG", "length": 366 }, "evidence": [ { "id": "A0A8V1A837", "url": "https://omabrowser.org/oma/group/A0A8V1A837/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96CX6-1", "protein_name": "Leucine-rich repeat-containing protein 58", "gene_name": "LRRC58", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEEAGAAVVTAGEAELNWSRLSVSTETLESELEARGEERRGAREALLRLLLPHNRLVSLPRALGSGFPHLQLLDVSGNALTALGPELLALRGLRTLLAKNNRLGGPSALPKGLAQSPLCRSLQVLNLSGNCFQEVPASLLELRALQTLSLGGNQLQSIPAEIENLQSLECLYLGGNFIKEIPPELGNLPSLNYLVLCDNKIQSIPPQLSQLHSLRSLSLHNNLLTYLPREILNLIHLEELSLRGNPLVVRFVRDLTYDPPTLLELAARTIKIRNISYTPYDLPGNLLRYLGSASNCPNPKCGGVYFDCCVRQIKFVDFCGKYRLPLMHYLCSPECSSPCSSASHSSTSQSESDSEDEASVAARRMQKVLLG", "length": 371 }, "evidence": [ { "id": "A0A8V1A837", "url": "https://omabrowser.org/oma/group/A0A8V1A837/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9W2U2-1", "protein_name": "Disease resistance R13L4/SHOC-2-like LRR domain-containing protein", "gene_name": "CT7080", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MEVYTSDSSDTDSREQKTLDFGRMSLDLVTLEDHLASPQKALLKSSGDIETMLLNHNRLVGLPRLLLQFGNLKILDLSSNAITTLPDAVCQLPLVTLIAKNNLLTNASLPKSLLTKMANGNGNGNATGGTNSTLKELNLSGNQLTHFPEQVTELRHLKYLYLGGNKISSVSKDIWKMQSLHVLSLGGNLISEVPEAVGSLNQLQALVLCDNLIEILPTSIARLKNLKSLLLHKNRLRHLPKDIVALKNLTELSLRDNPLVVRFVQDMALKPPTLLELAGRMVKASGQRPGPYDIPRTLAEYLNSANCCVNPNCKGVFFDNRVEHIKFVDFCGKYRVPLLQYLCSSKCIEPEQPAARGSSVPAASASSGFMMRKVLLG", "length": 377 }, "evidence": [ { "id": "A0A8V1A837", "url": "https://omabrowser.org/oma/group/A0A8V1A837/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A837", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A837" } ], "pmid": "" }, { "name": "Cul5-RING ubiquitin ligase complex", "id": "GO:0031466", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031466", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A837", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A837" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A837", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A837" } ], "pmid": "" }, { "name": "regulation of taurine biosynthetic process", "id": "GO:0062089", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0062089", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A837", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A837" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "ubiquitin-like ligase-substrate adaptor activity", "id": "GO:1990756", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990756", 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Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052557.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015154512", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015154512" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A867", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A867" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FAM19A3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A867", "locus": {} } ], "crossref": [ { "id": "A0A8V1A867", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A867", "database": "AlphaFoldDB", "categories": [] }, { "id": "419874", "url": "https://www.ncbi.nlm.nih.gov/gene/419874", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR020350", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020350", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051743", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051743", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:419874", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419874", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RWWCHME", "url": "https://omabrowser.org/oma/group/RWWCHME/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A867", "url": "https://www.orthodb.org/?gene=A0A8V1A867", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31770", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31770", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31770:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31770:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12020", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12020", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015154512", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015154512", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1A867", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A867", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A867-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A867-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSERDVQSLSRRVLVLTLCLTTLWGRLTLASTHHRSHSAHVEPGTCEVIAAHRCCNKNKIEERSQTVKCSCFPGQVAGTTRAAPSCVDASIVLQKWWCQMEPCLAGEECKVLPDLSGWSCSSGNKVKTTKVTR", "length": 133, "header": "tr|A0A8V1A867-1|A0A8V1A867_CHICK Isoform 1 of TAFA chemokine like family member 3 OS=Gallus gallus OX=9031 GN=FAM19A3 PE=3 SV=1 CANONICAL=A0A8V1A867-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A867-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A867/entry#A0A8V1A867-1", "sequence": { "sequence": "MSERDVQSLSRRVLVLTLCLTTLWGRLTLASTHHRSHSAHVEPGTCEVIAAHRCCNKNKIEERSQTVKCSCFPGQVAGTTRAAPSCVDASIVLQKWWCQMEPCLAGEECKVLPDLSGWSCSSGNKVKTTKVTR", "length": 133, "header": "tr|A0A8V1A867-1|A0A8V1A867_CHICK Isoform 1 of TAFA chemokine like family member 3 OS=Gallus gallus OX=9031 GN=FAM19A3 PE=3 SV=1 CANONICAL=A0A8V1A867-1" }, "locus": { "chromosome": "26", "start_pos": 3618014, "end_pos": 3612915, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066084.1", "url": "https://www.ensembl.org/id/ENSGALT00010066084.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040350.1", "url": "https://www.ensembl.org/id/ENSGALP00010040350.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:419874", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419874", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A9J7F2V3-1", "protein_name": "Chemokine-like protein TAFA-3", "gene_name": "Tafa3", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSERTSSSWSPGSWVLALCLAWLWTRLASASLQPPTATVLVKQGTCEVIAAHRCCNRNRIEERSQTVKCSCLSGQVAGTTRAKPSCVDASIVLQKWWCQMEPCLLGEECKVLPDLSGWSCSSGHKVKTTKVTR", "length": 133 }, "evidence": [ { "id": "A0A8V1A867", "url": "https://omabrowser.org/oma/group/A0A8V1A867/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "E7FC03-1", "protein_name": "Chemokine-like protein TAFA-2", "gene_name": "tafa3a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MRERELQRVGRRLLLLGICLLSLWGQFSLASTHRSHIVHVKAGTCEVIAAHRCCNKNKIEERSQTVKCSCFPGQVAGTTRAAPSCVDASIVAQKWWCQMQPCMDGEECKVLPDLKGWSCSTGNKVKTTKVTR", "length": 132 }, "evidence": [ { "id": "A0A8V1A867", "url": "https://omabrowser.org/oma/group/A0A8V1A867/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1LXB8-1", "protein_name": "TAFA chemokine like family member 3", "gene_name": "Tafa3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAERSTSNWSPGSWVLALCLAWLWTRLASASLQPPTSTVLVKQGTCEVIAAHRCCNRNRIEERSQTVKCSCLSGQVAGTTRAKPSCVDASIVLQKWWCQMEPCLLGEECKVLPDLSGWSCSRGHKVKTTKVTR", "length": 133 }, "evidence": [ { "id": "A0A8V1A867", "url": "https://omabrowser.org/oma/group/A0A8V1A867/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7TPG6-1", "protein_name": "Chemokine-like protein TAFA-3", "gene_name": "Tafa3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MERPTSNWSAGSWVLALCLAWLWTCPASASLQPPTSAVLVKQGTCEVIAAHRCCNRNRIEERSQTVKCSCLSGQVAGTTRAKPSCVDASIVLQKWWCQMEPCLLGEECKVLPDLSGWSCSSGHKVKTTKVTR", "length": 132 }, "evidence": [ { "id": "A0A8V1A867", "url": "https://omabrowser.org/oma/group/A0A8V1A867/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A867", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A867" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "receptor ligand activity", "id": "GO:0048018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048018", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A867", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A867" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A872-1", "uniprot_ac": "A0A8V1A872", "uniprot_id": "A0A8V1A872_CHICK", "mass": { "chemical_mass": 89429.0, "monoisotopic_mass": 89429.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Zinc finger protein 777", "type": "recommended", "evidence": [ { "id": "A0A8V1A872", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A872/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "May be involved in transcriptional regulation.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A872", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A872#function" }, { "database": "UniProtKB", "id": "ARBA00003767", "url": "https://www.uniprot.org/uniprotkb/ARBA00003767#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A872", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A872" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A872", "locus": {} } ], "crossref": [ { "id": "A0A8V1A872", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A872", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd07765", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07765", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001909", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001909", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036051", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036051", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR24399", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24399", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24399:SF70", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24399:SF70", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01352", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01352", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1A872", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A872", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A872-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A872-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTTGLGGPFPALFAPLSPPSPCRSHGAVSSTVGGGEVGTNPPQRGWFGPGPWRSPTYRYLHPLIVPSAGDPQPTGARSLWLSSPHGIPHPSASPSCGGASPTFGCPHLWGSPAQGLLRPSGPFPTYGPRPRGCSRPADAHTPSPQVPELGMRPRCPSPFQRGSSTCTSERETQTAELSLTVVTAVQAVERKVDSHATRLLDLEGRTGVAEKKLIDCEKTATELGNQLESKCAALGTLIQEYGLLQRRLENMENLLKNRNFWILRLPPGRKGEVPKVPVTFDDVSVCFNDKEWEKLEEWQKELYKNVMKGNYESLISLDYAISKPGVLSQIEQGEEPRVRNEQDLEESEMMSDATAAGIRVVIKTEELLPEDSPENPELHGMSGQSEGSFQSPDEEAACESPYGSVSPPRELPGTSLGDPSEYVGDYNEIQRVIVHHGSCTEDGVVIKTEEEEEDDVDEPCSMFSGRSDPPAFPSHEAGLGCEAQCSSKAAPRSLAAARVHKSPSCERDAGEMKPAMAQQQRNRTRERPYICPECGKSFMLKINFVIHQRNHLKEGPYECHECDLSFRNKQQFLLHQRSHTRRGVGVPRRPEHGLKAPARPPAPGKPYKCSECESSFSHKSSLSKHQITHVGERPFTCGECRRSFRLQISLIMHQRIHAGKNEMAFLCPQCGKNFTRPSHLLRHQRTHTGERPFQCSQCEKTFSEKSKLTNHYRIHTRERPHACAVCGKGFIRKHHLLEHQRIHTGERPYHCAECGKNFTQKHHLLEHQRAHTGERPYPCTECTKCFRYKQSLKYHLRTHVGE", "length": 802, "header": "tr|A0A8V1A872-1|A0A8V1A872_CHICK Isoform 1 of Zinc finger protein 777 OS=Gallus gallus OX=9031 GN= PE=3 SV=1 CANONICAL=A0A8V1A872-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A872-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A872/entry#A0A8V1A872-1", "sequence": { "sequence": "MTTGLGGPFPALFAPLSPPSPCRSHGAVSSTVGGGEVGTNPPQRGWFGPGPWRSPTYRYLHPLIVPSAGDPQPTGARSLWLSSPHGIPHPSASPSCGGASPTFGCPHLWGSPAQGLLRPSGPFPTYGPRPRGCSRPADAHTPSPQVPELGMRPRCPSPFQRGSSTCTSERETQTAELSLTVVTAVQAVERKVDSHATRLLDLEGRTGVAEKKLIDCEKTATELGNQLESKCAALGTLIQEYGLLQRRLENMENLLKNRNFWILRLPPGRKGEVPKVPVTFDDVSVCFNDKEWEKLEEWQKELYKNVMKGNYESLISLDYAISKPGVLSQIEQGEEPRVRNEQDLEESEMMSDATAAGIRVVIKTEELLPEDSPENPELHGMSGQSEGSFQSPDEEAACESPYGSVSPPRELPGTSLGDPSEYVGDYNEIQRVIVHHGSCTEDGVVIKTEEEEEDDVDEPCSMFSGRSDPPAFPSHEAGLGCEAQCSSKAAPRSLAAARVHKSPSCERDAGEMKPAMAQQQRNRTRERPYICPECGKSFMLKINFVIHQRNHLKEGPYECHECDLSFRNKQQFLLHQRSHTRRGVGVPRRPEHGLKAPARPPAPGKPYKCSECESSFSHKSSLSKHQITHVGERPFTCGECRRSFRLQISLIMHQRIHAGKNEMAFLCPQCGKNFTRPSHLLRHQRTHTGERPFQCSQCEKTFSEKSKLTNHYRIHTRERPHACAVCGKGFIRKHHLLEHQRIHTGERPYHCAECGKNFTQKHHLLEHQRAHTGERPYPCTECTKCFRYKQSLKYHLRTHVGE", "length": 802, "header": "tr|A0A8V1A872-1|A0A8V1A872_CHICK Isoform 1 of Zinc finger protein 777 OS=Gallus gallus OX=9031 GN= PE=3 SV=1 CANONICAL=A0A8V1A872-1" }, "locus": { "chromosome": "2", "start_pos": 610055, "end_pos": 603723, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066089.1", "url": "https://www.ensembl.org/id/ENSGALT00010066089.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040355.1", "url": "https://www.ensembl.org/id/ENSGALP00010040355.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A872", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A872" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A872", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A872" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A872", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A872" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A872", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A872" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A872", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A872" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A872", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A872" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A872", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A872" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 522, "end_pos": 524, "annotation": "n_glycosylation_sequon" }, { "start_pos": 673, "end_pos": 675, "annotation": "n_glycosylation_sequon" }, { "start_pos": 757, "end_pos": 759, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], 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This record is derived from a genomic sequence (NC_052559.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_046760547", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046760547" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A8A4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8A4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "HAUS8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8A4", "locus": { "chromosome": "28", "start_pos": 4657813, "end_pos": 4648994, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027273", "url": "https://www.ensembl.org/id/ENSGALG00010027273" } ] } } ], "crossref": [ { "id": "A0A8V1A8A4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A8A4", "database": 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"database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-380284", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-380284", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-380320", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-380320", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5620912", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5620912", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-8854518", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8854518", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_046760547", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046760547", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1A8A4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8A4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A8A4-1", "url": 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] } }, { "isoform_ac": "A0A8V1ADQ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8A4/entry#A0A8V1ADQ2-1", "sequence": { "sequence": "MSALADGETSQNKRKGRRVVKSRYLQYDKKGSSKNSSTKSFLSSTSSSSSAARTSSLLSQKSETAGLASGLLNQSSFEKGDLQSTLLDGDKITRPDLDLSAINDKAVRQKATSPKASCKTDKGTCVNKQKSKNNPVVVGAELGSQELILTYLGVKQRKDVAQLEEKAEENLLMLCEEKERQQEKLYELKREILLKEREEKLDEELVKQMELLSPLVPLLGRFKEQYKSFAVALDATRHKLPIKNIHIDGDMPTYLDKLQEQLTVTQELLAEVMPDSSEESAKAFSELQDTEDVFKKLEKELQRSFTQVQNLSYEASKEVSLHNQRICEDNHGVEVVKHWYFN", "length": 342, "header": "tr|A0A8V1ADQ2-1|A0A8V1ADQ2_CHICK Computationally mapped isoform of HAUS augmin like complex subunit 8 OS=Gallus gallus OX=9031 GN=HAUS8 PE=1 SV=1 CANONICAL=A0A8V1A8A4-1" }, "locus": { "chromosome": "28", "start_pos": 4655797, "end_pos": 4650117, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066125.1", "url": "https://www.ensembl.org/id/ENSGALT00010066125.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040391.1", "url": 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This record is derived from a genomic sequence (NC_052539.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. 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[ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "A0A8V1A8C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8C0/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A8C0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8C0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8C0", "locus": {} } ], "crossref": [ { "id": "A0A8V1A8C0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A8C0", "database": "AlphaFoldDB", "categories": [] }, { "id": "A0A8V1A8C0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8C0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A8C0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8C0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "SCVGCSWTRCVGASPSVQQSWVGCWLAVGFWKKKKKKEQNNETLGSKSMGAGAAGGCAEGRREAEGFSCFVGTVLGEADNDTITRNLYLHTKILIALVFFILKFA", "length": 105, "header": "tr|A0A8V1A8C0-1|A0A8V1A8C0_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1A8C0-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A8C0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8C0/entry#A0A8V1A8C0-1", "sequence": { "sequence": "SCVGCSWTRCVGASPSVQQSWVGCWLAVGFWKKKKKKEQNNETLGSKSMGAGAAGGCAEGRREAEGFSCFVGTVLGEADNDTITRNLYLHTKILIALVFFILKFA", "length": 105, "header": "tr|A0A8V1A8C0-1|A0A8V1A8C0_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1A8C0-1" }, "locus": { "chromosome": "2", "start_pos": 761002, "end_pos": 759869, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066145.1", "url": "https://www.ensembl.org/id/ENSGALT00010066145.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040411.1", "url": "https://www.ensembl.org/id/ENSGALP00010040411.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 41, "end_pos": 43, "annotation": "n_glycosylation_sequon" }, { "start_pos": 80, "end_pos": 82, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 41, "end_pos": 43 }, { "start_pos": 80, "end_pos": 82 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A8C2-1", "uniprot_ac": "A0A8V1A8C2", "uniprot_id": "A0A8V1A8C2_CHICK", "mass": { "chemical_mass": 123465.0, "monoisotopic_mass": 123465.0 }, "refseq": { "ac": "XP_024997091", "name": "DENN domain-containing protein 1A isoform X4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024997091" }, "gene_names": [ { "name": "DENND1A", "type": "recommended", "evidence": [ { "id": "A0A8V1A8C2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8C2" } ] }, { "name": "DENND1A", "type": "synonym", "evidence": [ { "id": "XP_024997091", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024997091" } ] } ], "protein_names": [ { "name": "DENN domain containing 1A", "type": "synonym", "evidence": [ { "id": "A0A8V1A8C2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8C2/entry#names_and_taxonomy" } ] }, { "name": "DENN domain-containing protein 1A isoform X4", "type": "synonym", "evidence": [ { "id": "XP_024997091", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024997091" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052548.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_024997091", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024997091" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A8C2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8C2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "DENND1A", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8C2", "locus": { "chromosome": "17", "start_pos": 9629168, "end_pos": 9806368, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028346", "url": "https://www.ensembl.org/id/ENSGALG00010028346" } ] } } ], "crossref": [ { "id": "A0A8V1A8C2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A8C2", "database": "AlphaFoldDB", "categories": [] }, { "id": "417102", "url": "https://www.ncbi.nlm.nih.gov/gene/417102", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001194", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001194", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005112", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005112", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005113", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005113", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037516", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037516", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040032", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040032", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043153", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043153", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A8C2", "url": "https://www.orthodb.org/?gene=A0A8V1A8C2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A8C6", "url": "https://www.orthodb.org/?gene=A0A8V1A8C6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ADG0", "url": "https://www.orthodb.org/?gene=A0A8V1ADG0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ADG5", "url": "https://www.orthodb.org/?gene=A0A8V1ADG5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AG17", "url": "https://www.orthodb.org/?gene=A0A8V1AG17", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AIB6", "url": "https://www.orthodb.org/?gene=A0A8V1AIB6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AK59", "url": "https://www.orthodb.org/?gene=A0A8V1AK59", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13196", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13196", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13196:SF22", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13196:SF22", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02141", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02141", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03455", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03455", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03456", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03456", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-8876198", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8876198", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_024997091", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024997091", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1A8C2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8C2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A8C2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8C2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A8C6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8C6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A8C6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8C6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ADG0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADG0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ADG0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADG0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ADG5", "url": 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"database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGSRIKQNPETTFEVYAEVTYSGISCIGKDPEVRRQFPEDYSDQEVLQTLTKFCFPFYVDSHAVSQVGQNFTFVLTDIDSKQRFGFCRLSSGAKSCFCILSYLPWFEVFYKLLNVLADYSAKGQDNQRSELLETFHKLSIPEPKTPVQLGLHSYFTVPDIRELPSIPENRNLTEYFVAVDVNNMLHLYASMLYERRILICCSKLSTLTACIHGSAAMLYPMFWQHVYIPVLPPHLLDYCCAPMPYLIGIHLSLMEKVRNMALEDVVILNVDTNTLETPFDDLQSLPNDVVSALKNRLKKVSTTTGDGVARAFLKAQASFFGSYRNALKIEPGEPITFCEETFVSHRSAVMRQFLQNAIQLQLFKQFIDGRLDLLNSGEGFSDAFEEEINMGEYAGSDKLYLQWLSTVRKGSGAILNTVKTKANPAMKTVYKFAKDHAKMGIKEVKNRLKQKDIAENGCSAAPEQSLPRPAPSPLVEKKDTKLREDRRPITVHFGQQQRLRPPRPPPPKIQRSTRPVRPPRPHIVKRPKSNIAVEARRTSISSPEHLVKPMRHYTVFLSEDSSDDEFQQEEDPVSGFSENFFFSAPFEWPQPYRALKESDSADGEEAVSPEKAKEPLPPSPLLLSNATEINLLEDIFPNLEVETQPQPLSQAKSLEDLRTPKEETDQRCTFDYQRMDLAGSERNRIVPPMKLSHPYNKLWNMGHDDMAIPTKYSQSSPERPLTALGNVPPITRRPRSRDSILAPAEKDDSNPTAQGNITIPRPQGRKTPELGIVPPPPAPRASKHQTPTGPTEILSTHTTGCSQLVSDLIPEPLGVARLSLEPEGQQSVNYSPCSSQLLSSATSTAEMLQPVKVKTDNTGNESDYLLNLLDPLKTANWQSSGPQQGSCSLQSSATPPSGAGFAAVASDFVTPPAAPFVQSLSYPSPALPPFLQASPNPFTQTVPGPLSVSLVRPPRGSFTPTLGHAYSSSFITPNSSFYPPHRPQPNISTLSMPNLFSQAPAMSPASSLLLQSHSPSPASSLQPACLSGPSKTRTLQVGKSSSKVDTKQALALLSNEPPLIPSRPAKGLESVLLSSKSEETKDPFEDLLKKTKQDVSSTPGKVEQLRRQWETFE", "length": 1113, "header": "tr|A0A8V1A8C2-1|A0A8V1A8C2_CHICK Isoform 1 of DENN domain containing 1A OS=Gallus gallus OX=9031 GN=DENND1A PE=4 SV=1 CANONICAL=A0A8V1A8C2-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A8C2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8C2/entry#A0A8V1A8C2-1", "sequence": { "sequence": "MGSRIKQNPETTFEVYAEVTYSGISCIGKDPEVRRQFPEDYSDQEVLQTLTKFCFPFYVDSHAVSQVGQNFTFVLTDIDSKQRFGFCRLSSGAKSCFCILSYLPWFEVFYKLLNVLADYSAKGQDNQRSELLETFHKLSIPEPKTPVQLGLHSYFTVPDIRELPSIPENRNLTEYFVAVDVNNMLHLYASMLYERRILICCSKLSTLTACIHGSAAMLYPMFWQHVYIPVLPPHLLDYCCAPMPYLIGIHLSLMEKVRNMALEDVVILNVDTNTLETPFDDLQSLPNDVVSALKNRLKKVSTTTGDGVARAFLKAQASFFGSYRNALKIEPGEPITFCEETFVSHRSAVMRQFLQNAIQLQLFKQFIDGRLDLLNSGEGFSDAFEEEINMGEYAGSDKLYLQWLSTVRKGSGAILNTVKTKANPAMKTVYKFAKDHAKMGIKEVKNRLKQKDIAENGCSAAPEQSLPRPAPSPLVEKKDTKLREDRRPITVHFGQQQRLRPPRPPPPKIQRSTRPVRPPRPHIVKRPKSNIAVEARRTSISSPEHLVKPMRHYTVFLSEDSSDDEFQQEEDPVSGFSENFFFSAPFEWPQPYRALKESDSADGEEAVSPEKAKEPLPPSPLLLSNATEINLLEDIFPNLEVETQPQPLSQAKSLEDLRTPKEETDQRCTFDYQRMDLAGSERNRIVPPMKLSHPYNKLWNMGHDDMAIPTKYSQSSPERPLTALGNVPPITRRPRSRDSILAPAEKDDSNPTAQGNITIPRPQGRKTPELGIVPPPPAPRASKHQTPTGPTEILSTHTTGCSQLVSDLIPEPLGVARLSLEPEGQQSVNYSPCSSQLLSSATSTAEMLQPVKVKTDNTGNESDYLLNLLDPLKTANWQSSGPQQGSCSLQSSATPPSGAGFAAVASDFVTPPAAPFVQSLSYPSPALPPFLQASPNPFTQTVPGPLSVSLVRPPRGSFTPTLGHAYSSSFITPNSSFYPPHRPQPNISTLSMPNLFSQAPAMSPASSLLLQSHSPSPASSLQPACLSGPSKTRTLQVGKSSSKVDTKQALALLSNEPPLIPSRPAKGLESVLLSSKSEETKDPFEDLLKKTKQDVSSTPGKVEQLRRQWETFE", "length": 1113, "header": "tr|A0A8V1A8C2-1|A0A8V1A8C2_CHICK Isoform 1 of DENN domain containing 1A OS=Gallus gallus OX=9031 GN=DENND1A PE=4 SV=1 CANONICAL=A0A8V1A8C2-1" }, "locus": { "chromosome": "17", "start_pos": 9806229, "end_pos": 9631076, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068664.1", "url": "https://www.ensembl.org/id/ENSGALT00010068664.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042202.1", "url": "https://www.ensembl.org/id/ENSGALP00010042202.1" } ] } }, { "isoform_ac": "A0A8V1A8C6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8C2/entry#A0A8V1A8C6-1", "sequence": { "sequence": "MGSRIKQNPETTFEVYAEVTYSGISCIGKDPEVRRQFPEDYSDQEVLQTLTKFCFPFYVDSHAVSQVGQNFTFVLTDIDSKQRFGFCRLSSGAKSCFCILSYLPWFEVFYKLLNVLADYSAKGQDNQRSELLETFHKLSIPEPKTPVQLGLHSYFTVPDIRELPSIPENRNLTEYFVAVDVNNMLHLYASMLYERRILICCSKLSTLTACIHGSAAMLYPMFWQHVYIPVLPPHLLDYCCAPMPYLIGIHLSLMEKVRNMALEDVVILNVDTNTLETPFDDLQSLPNDVVSALKNRLKKVSTTTGDGVARAFLKAQASFFGSYRNALKIEPGEPITFCEETFVSHRSAVMRQFLQNAIQLQLFKQFIDGRLDLLNSGEGFSDAFEEEINMGEYAGSDKLYLQWLSTVRKGSGAILNTVKTKANPAMKTVYKFAKDHAKMGIKEVKNRLKQKDIAENGCSAAPEQSLPRPAPSPLVEKKDTKLREDRRPITVHFGQFCDVLNSEDTLTGHSNCCSCESWCVQVRPPRPHIVKRPKSNIAVEARRTSISSPEQPQPYRALKESDSADGEEAVSPEKAKEPLPPSPLLLSNATEINLLEDIFPNLEVETQPQPLSQAKSLEDLRTPKEETDQRCTFDYQRMDLAGSERNRIVPPMKLSHPYNKLWNMGHDDMAIPTKYSQSSPERPLTALGNVPPITRRPRSRDSILAPAEKDDSNPTAQGNITIPRPQGRKTPELGIVPPPPAPRASKHQTPTGPTEILSTHTTGCSQLVSDLIPEPLGVARLSLEPEGQQSVNYSPCSSQLLSSATSTAEMLQPVKVKTDNTGNESDYLLNLLDPLKTANWQSSGPQQGSCSLQSSATPPSGAGFAAVASDFVTPPAAPFVQSLSYPSPALPPFLQASPNPFTQTVPGPLSVSLVRPPRGSFTPTLGHAYSSSFITPNSSFYPPHRPQPNISTLSMPNLFSQAPAMSPASSLLLQSHSPSPASSLQPACLSGPSKTRTLQVGKSSSKVDTKQALALLSNEPPLIPSRPAKGLESVLLSSKSEETKDPFEDLLKKTKQDVSSTPGKVEQLRRQWETFE", "length": 1076, "header": "tr|A0A8V1A8C6-1|A0A8V1A8C6_CHICK Computationally mapped isoform of DENN domain containing 1A OS=Gallus gallus OX=9031 GN=DENND1A PE=4 SV=1 CANONICAL=A0A8V1A8C2-1" }, "locus": { "chromosome": "17", "start_pos": 9806229, "end_pos": 9631076, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068669.1", "url": "https://www.ensembl.org/id/ENSGALT00010068669.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042207.1", "url": "https://www.ensembl.org/id/ENSGALP00010042207.1" } ] } }, { "isoform_ac": "A0A8V1ADG0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8C2/entry#A0A8V1ADG0-1", "sequence": { "sequence": "MLMQDYIFLVIEVLQTLTKFCFPFYVDSHAVSQVGQNFTFVLTDIDSKQRFGFCRLSSGAKSCFCILSYLPWFEVFYKLLNVLADYSAKGQDNQRSELLETFHKLSIPEPKTPVQLGLHSYFTVPDIRELPSIPENLTACIHGSAAMLYPMFWQHVYIPVLPPHLLDYCCAPMPYLIGIHLSLMEKVRNMALEDVVILNVDTNTLETPFDDLQSLPNDVVSALKNRLKKVSTTTGDGVARAFLKAQASFFGSYRNALKIEPGEPITFCEETFVSHRSAVMRQFLQNAIQLQLFKQFIDGRLDLLNSGEGFSDAFEEEINMGEYAGSDKLYLQWLSTVRKGSGAILNTVKTKANPAMKTVYKFAKDHAKMGIKEVKNRLKQKDIAENGCSAAPEQSLPRPAPSPLVEKKDTKLREDRRPITVHFGQVRPPRPHIVKRPKSNIAVEARRTSISSPEQPQPYRALKESDSADGEEAVSPEKAKEPLPPSPLLLSNATEINLLEDIFPNLEVETQPQPLSQAKSLEDLRTPKEETDQRCTFDYQRMDLAGSERNRIVPPMKLSHPYNKLWNMGHDDMAIPTKYSQSSPERPLTALGNVPPITRRPRSRDSILAPAEKDDSNPTAQGNITIPRPQGRKTPELGIVPPPPAPRASKHQTPTGPTEILSTHTTGCSQLVSDLIPEPLGVARLSLEPEGQQSVNYSPCSSQLLSSATSTAEMLQPVKVKTDNTGNESDYLLNLLDPLKTANWQSSGPQQGSCSLQSSATPPSGAGFAAVASDFVTPPAAPFVQSLSYPSPALPPFLQASPNPFTQTVPGPLSVSLVRPPRGSFTPTLGHAYSSSFITPNSSFYPPHRPQPNISTLSMPNLFSQAPAMSPASSLLLQSHSPSPASSLQPACLSGPSKTRTLQVGKSSSKVDTKQALALLSNEPPLIPSRPAKGLESVLLSSKSEETKDPFEDLLKKTKQDVSSTPGKVEQLRRQWETFE", "length": 980, "header": "tr|A0A8V1ADG0-1|A0A8V1ADG0_CHICK Computationally mapped isoform of DENN domain containing 1A OS=Gallus gallus OX=9031 GN=DENND1A PE=4 SV=1 CANONICAL=A0A8V1A8C2-1" }, "locus": { "chromosome": "17", "start_pos": 9765573, "end_pos": 9631076, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068666.1", "url": "https://www.ensembl.org/id/ENSGALT00010068666.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042204.1", "url": "https://www.ensembl.org/id/ENSGALP00010042204.1" } ] } }, { "isoform_ac": "A0A8V1ADG5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8C2/entry#A0A8V1ADG5-1", "sequence": { "sequence": "MGSRIKQNPETTFEVYAEVTYSGISCIGKDPEVRRQFPEDYSDQEVLQTLTKFCFPFYVDSHAVSQVGQNFTFVLTDIDSKQRFGFCRLSSGAKSCFCILSYLPWFEVFYKLLNVLADYSAKGQDNQRSELLETFHKLSIPEPKTPVQLGLHSYFTVPDIRELPSIPENRNLTEYFVAVDVNNMLHLYASMLYERRILICCSKLSTLTACIHGSAAMLYPMFWQHVYIPVLPPHLLDYCCAPMPYLIGIHLSLMEKVRNMALEDVVILNVDTNTLETPFDDLQSLPNDVVSALKNRLKKVSTTTGDGVARAFLKAQASFFGSYRNALKIEPGEPITFCEETFVSHRSAVMRQFLQNAIQLQLFKQFIDGRLDLLNSGEGFSDAFEEEINMGEYAGSDKLYLQWLSTVRKGSGAILNTVKTKANPAMKTVYKFAKDHAKMGIKEVKNRLKQKDIAENGCSAAPEQSLPRPAPSPLVEKKDTKLREDRRPITVHFGQVRPPRPHIVKRPKSNIAVEARRTSISSPEQPQPYRALKESDSADGEEAVSPEKAKEPLPPSPLLLSNATEINLLEDIFPNLEVETQPQPLSQAKSLEDLRTPKEETDQRCTFDYQRMDLAGSERNRIVPPMKLSHPYNKLWNMGHDDMAIPTKYSQSSPERPLTALGNVPPITRRPRSRDSILAPAEKDDSNPTAQGNITIPRPQGRKTPELGIVPPPPAPRASKHQTPTGPTEILSTHTTGCSQLVSDLIPEPLGVARLSLEPEGQQSVNYSPCSSQLLSSATSTAEMLQPVKVKTDNTGNESDYLLNLLDPLKTANWQSSGPQQGSCSLQSSATPPSGAGFAAVASDFVTPPAAPFVQSLSYPSPALPPFLQASPNPFTQTVPGPLSVSLVRPPRGSFTPTLGHAYSSSFITPNSSFYPPHRPQPNISTLSMPNLFSQAPAMSPASSLLLQSHSPSPASSLQPACLSGPSKTRTLQVGKSSSKVDTKQALALLSNEPPLIPSRPAKGLESVLLSSKSEETKDPFEDLLKKTKQDVSSTPGKVEQLRRQWETFE", "length": 1050, "header": "tr|A0A8V1ADG5-1|A0A8V1ADG5_CHICK Computationally mapped isoform of DENN domain containing 1A OS=Gallus gallus OX=9031 GN=DENND1A PE=4 SV=1 CANONICAL=A0A8V1A8C2-1" }, "locus": { "chromosome": "17", "start_pos": 9806229, "end_pos": 9631076, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068671.1", "url": "https://www.ensembl.org/id/ENSGALT00010068671.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042209.1", "url": "https://www.ensembl.org/id/ENSGALP00010042209.1" } ] } }, { "isoform_ac": "A0A8V1AG17-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8C2/entry#A0A8V1AG17-1", "sequence": { "sequence": "MGSRIKQNPETTFEVYAEVTYSGISCIGKDPEVRRQFPEDYSDQEVLQTLTKFCFPFYVDSHAVSQVGQNFTFVLTDIDSKQRFGFCRLSSGAKSCFCILRIIKGVSFWKHFINLASLSQKLPFSLDCTLTLLCLTSESFLVYLKINLTEYFVAVDVNNMLHLYASMLYERRILICCSKLSTLTACIHGSAAMLYPMFWQHVYIPVLPPHLLDYCCAPMPYLIGIHLSLMEKVRNMALEDVVILNVDTNTLETPFDDLQSLPNDVVSALKNRLKKVSTTTGDGVARAFLKAQASFFGSYRNALKIEPGEPITFCEETFVSHRSAVMRQFLQNAIQLQLFKQFIDGRLDLLNSGEGFSDAFEEEINMGEYAGSDKLYLQWLSTVRKGSGAILNTVKTKANPAMKTVYKFAKDHAKMGIKEVKNRLKQKDIAENGCSAAPEQSLPRPAPSPLVEKKDTKLREDRRPITVHFGQVRPPRPHIVKRPKSNIAVEARRTSISSPEQPQPYRALKESDSADGEEAVSPEKAKEPLPPSPLLLSNATEINLLEDIFPNLEVETQPQPLSQAKSLEDLRTPKEETDQRCTFDYQRMDLAGSERNRIVPPMKLSHPYNKLWNMGHDDMAIPTKYSQSSPERPLTALGNVPPITRRPRSRDSILAPAEKDDSNPTAQGNITIPRPQGRKTPELGIVPPPPAPRASKHQTPTGPTEILSTHTTGCSQLVSDLIPEPLGVARLSLEPEGQQSVNYSPCSSQLLSSATSTAEMLQPVKVKTDNTGNESDYLLNLLDPLKTANWQSSGPQQGSCSLQSSATPPSGAGFAAVASDFVTPPAAPFVQSLSYPSPALPPFLQASPNPFTQTVPGPLSVSLVRPPRGSFTPTLGHAYSSSFITPNSSFYPPHRPQPNISTLSMPNLFSQAPAMSPASSLLLQSHSPSPASSLQPACLSGPSKTRTLQVGKSSSKVDTKQALALLSNEPPLIPSRPAKGLESVLLSSKSEETKDPFEDLLKKTKQDVSSTPGKVEQLRRQWETFE", "length": 1026, "header": "tr|A0A8V1AG17-1|A0A8V1A8C2_CHICK Computationally mapped isoform of DENN domain containing 1A OS=Gallus gallus OX=9031 GN=DENND1A PE=4 SV=1 CANONICAL=A0A8V1A8C2-1" }, "locus": { "chromosome": "17", "start_pos": 9806229, "end_pos": 9631076, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068663.1", "url": "https://www.ensembl.org/id/ENSGALT00010068663.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042201.1", "url": "https://www.ensembl.org/id/ENSGALP00010042201.1" } ] } }, { "isoform_ac": "A0A8V1AIB6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8C2/entry#A0A8V1AIB6-1", "sequence": { "sequence": "MGSRIKQNPETTFEVYAEVTYSGISCIGKDPEVRRQFPEDYSDQEVLQTLTKFCFPFYVDSHAVSQVGQNFTFVLTDIDSKQRFGFCRLSSGAKSCFCILSYLPWFEVFYKLLNVLADYSAKGQDNQRSELLETFHKLSIPEPKTPVQLGLHSYFTVPDIRELPSIPENRNLTEYFVAVDVNNMLHLYASMLYERRILICCSKLSTLTACIHGSAAMLYPMFWQHVYIPVLPPHLLDYC", "length": 239, "header": "tr|A0A8V1AIB6-1|A0A8V1A8C2_CHICK Computationally mapped isoform of DENN domain containing 1A OS=Gallus gallus OX=9031 GN=DENND1A PE=4 SV=1 CANONICAL=A0A8V1A8C2-1" }, "locus": { "chromosome": "17", "start_pos": 9806229, "end_pos": 9720081, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068661.1", "url": "https://www.ensembl.org/id/ENSGALT00010068661.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042200.1", "url": "https://www.ensembl.org/id/ENSGALP00010042200.1" } ] } }, { "isoform_ac": "A0A8V1AK59-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8C2/entry#A0A8V1AK59-1", "sequence": { "sequence": "MGSRIKQNPETTFEVYAEVTYSGISCIGKDPEVRRQFPEDYSDQEVLQTLTKFCFPFYVDSHAVSQVGQNFTFVLTDIDSKQRFGFCRLSSGAKSCFCILSYLPWFEVFYKLLNVLADYSAKGQDNQRSELLETFHKLSIPEPKTPVQLGLHSYFTVPDIRELPSIPENRNLTEYFVAVDVNNMLHLYASMLYERRILICCSKLSTLTACIHGSAAMLYPMFWQHVYIPVLPPHLLDYCCAPMPYLIGIHLSLMEKVRNMALEDVVILNVDTNTLETPFDDLQSLPNDVVSALKNRLKKVSTTTGDGVARAFLKAQASFFGSYRNALKIEPGEPITFCEETFVSHRSAVMRQFLQNAIQLQLFKQFIDGRLDLLNSGEGFSDAFEEEINMGEYAGSDKLYLQWLSTVRKGSGAILNTVKTKANPAMKTVYKFAKDHAKMGIKEVKNRLKQKDIAENGCSAAPEQSLPRPAPSPLVEKKDTKLREDRRPITVHFGQFCDVLNSEDTLTGHSNCCSCESWCVQQQRLRPPRPPPPKIQRSTRPVRPPRPHIVKRPKSNIAVEARRTSISSPEQPQPYRALKESDSADGEEAVSPEKAKEPLPPSPLLLSNATEINLLEDIFPNLEVETQPQPLSQAKSLEDLRTPKEETDQRCTFDYQRMDLAGSERNRIVPPMKLSHPYNKLWNMGHDDMAIPTKYSQSSPERPLTALGNVPPITRRPRSRDSILAPAEKDDSNPTAQGNITIPRPQGRKTPELGIVPPPPAPRASKHQTPTGPTEILSTHTTGCSQLVSDLIPEPLGVARLSLEPEGQQSVNYSPCSSQLLSSATSTAEMLQPVKVKTDNTGNESDYLLNLLDPLKTANWQSSGPQQGSCSLQSSATPPSGAGFAAVASDFVTPPAAPFVQSLSYPSPALPPFLQASPNPFTQTVPGPLSVSLVRPPRGSFTPTLGHAYSSSFITPNSSFYPPHRPQPNISTLSMPNLFSQAPAMSPASSLLLQSHSPSPASSLQPACLSGPSKTRTLQVGKSSSKVDTKQALALLSNEPPLIPSRPAKGLESVLLSSKSEETKDPFEDLLKKTKQDVSSTPGKVEQLRRQWETFE", "length": 1096, "header": "tr|A0A8V1AK59-1|A0A8V1A8C2_CHICK Computationally mapped isoform of DENN domain containing 1A OS=Gallus gallus OX=9031 GN=DENND1A PE=4 SV=1 CANONICAL=A0A8V1A8C2-1" }, "locus": { "chromosome": "17", "start_pos": 9806229, "end_pos": 9631076, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068665.1", "url": "https://www.ensembl.org/id/ENSGALT00010068665.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042203.1", "url": "https://www.ensembl.org/id/ENSGALP00010042203.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1098, "start_aa": "Thr", "end_pos": 1098, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1098", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-GGA-8876198", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8876198", "resource": "Reactome", "description": "RAB GEFs exchange GTP for GDP on RABs" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A8C2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8C2" } ], "pmid": "" }, { "name": "dendrite", "id": "GO:0030425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A8C2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8C2" } ], "pmid": "" }, { "name": "neuronal cell body", "id": "GO:0043025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043025", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A8C2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8C2" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A8C2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8C2" } ], "pmid": "" }, { "name": "clathrin-coated vesicle", "id": "GO:0030136", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030136", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A8C2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8C2" } ], "pmid": "" }, { "name": "clathrin-coated vesicle membrane", "id": "GO:0030665", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030665", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A8C2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8C2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "endocytosis", "id": "GO:0006897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006897", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A8C2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8C2" } ], "pmid": "" }, { "name": "endocytic recycling", "id": "GO:0032456", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032456", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A8C2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8C2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "SH3 domain binding", "id": "GO:0017124", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017124", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A8C2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8C2" } ], "pmid": "" }, { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A8C2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8C2" } ], "pmid": "" }, { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A8C2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8C2" } ], "pmid": "" }, { "name": "phosphatidylinositol phosphate binding", "id": "GO:1901981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901981", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A8C2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8C2" } ], "pmid": "" }, { "name": "phosphatidylinositol-3-phosphate binding", "id": "GO:0032266", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032266", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A8C2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8C2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 171, "end_pos": 173, "annotation": "n_glycosylation_sequon" }, { "start_pos": 625, "end_pos": 627, "annotation": "n_glycosylation_sequon" }, { "start_pos": 70, "end_pos": 72, "annotation": "n_glycosylation_sequon" }, { "start_pos": 756, "end_pos": 758, "annotation": "n_glycosylation_sequon" }, { "start_pos": 829, "end_pos": 831, "annotation": "n_glycosylation_sequon" }, { "start_pos": 860, "end_pos": 862, "annotation": "n_glycosylation_sequon" }, { "start_pos": 974, "end_pos": 976, "annotation": "n_glycosylation_sequon" }, { "start_pos": 986, "end_pos": 988, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1A8C2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8C2" }, { "id": "PS50211", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50211" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "UDENN", 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"protein_names": [ { "name": "Guanylyl cyclase domain containing 1", "type": "synonym", "evidence": [ { "id": "A0A8V1A8C8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8C8/entry#names_and_taxonomy" } ] }, { "name": "protein GUCD1", "type": "synonym", "evidence": [ { "id": "XP_040540900", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040540900" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052587.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040540900", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040540900" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A8C8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8C8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "GUCD1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8C8", "locus": { "chromosome": "15", "start_pos": 8447839, "end_pos": 8438858, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010026403", "url": "https://www.ensembl.org/id/ENSGALG00010026403" } ] } } ], "crossref": [ { "id": "A0A8V1A8C8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A8C8", "database": 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Guanylyl cyclase domain containing 1 OS=Gallus gallus OX=9031 GN=GUCD1 PE=4 SV=1 CANONICAL=A0A8V1A8C8-1" }, "locus": { "chromosome": "15", "start_pos": 8445263, "end_pos": 8439057, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010064231.1", "url": "https://www.ensembl.org/id/ENSGALT00010064231.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039475.1", "url": "https://www.ensembl.org/id/ENSGALP00010039475.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:416948", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416948", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287B1P5-1", "protein_name": "Guanylyl cyclase domain containing 1", "gene_name": "GUCD1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": 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"https://omabrowser.org/oma/group/A0A8V1A8C8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3HY22-1", "protein_name": "Protein GUCD1 isoform X3", "gene_name": "Gucd1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MVLRYLGQLDDGEFQNALQELQLTRSIWTIDLAYLMRHFGVRHRFCTQTLGVDKGYKNQSFYRKHFDTEETRVNQLFAQAKACKVRVEKCTVSVQDIQAHLAQGHVAIVLVNSGVLHCDLCSSPVKYCCFTPSGHRCFCRTPDYQGHFIVLRGYNRATGCIFYNNPAYADRMCSTSISNFEEARTSYGTDEDILFVYLDS", "length": 200 }, "evidence": [ { "id": "A0A8V1A8C8", "url": "https://omabrowser.org/oma/group/A0A8V1A8C8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q8BZI6-1", "protein_name": "Protein GUCD1", "gene_name": "Gucd1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRTEAEAAGQPLEPGDFVQLPVPIIQQLYHWDCGLACSRMVLRYLGQLDDGEFENALQELQLTRSIWTIDLAYLMRHFGVRHRFCTQTLGVDKGYKNQSFYRKHFDTEETRVNQLFAQAKACKVQVEKCTVSVQDIQVHLAQGHVAIVLVNSGVLHCDLCSSPVKYCCFTPSGHRCFCRTPDYQGHFIVLRGYNRATGCIFYNNPAYADRMCSTSISNFEEARTSYGTDEDILFVYLDS", "length": 239 }, "evidence": [ { "id": "A0A8V1A8C8", "url": "https://omabrowser.org/oma/group/A0A8V1A8C8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8L870-1", "protein_name": "Guanylyl cyclase 1", "gene_name": "GC1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MWPLCFLLNKLLRVEERNQGILDGNGDSTFPKYCLFDDPLVSDGKYRDAGLPSSSHMDVPHVHQLASWDCGLACVLMVLRASGIASCTLEDLAEICSTNSIWTVDLAYLLQKFCVEFSYYTITFGANPNYSIEEFYKEQLPEDLVRVDLLFRKAHESGIIIQCRSVSIHEISCLLLSGNYIAIALVDQDKLSKSWLEEVLVSGLHSSNSCYTGHYVVICGYDAVRDEFEIRDPASSKIHERISSKCLENARKSFGTDEDLLLINLENMRNQNGY", "length": 274 }, "evidence": [ { "id": "A0A8V1A8C8", "url": "https://omabrowser.org/oma/group/A0A8V1A8C8/", "database": 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"MNGLPPSKHYNLTHYQQRYNWDCGLSCIIMILSAQQREQLLGNFDAVCGEEGFGSSTWTIDLCYLLMRYQVRHEYFTQTLGIDPNYAQHTYYSKIIDKDERRVTRKFKDARAHGLRVEQRTVDMEVILRHLARHGPVILLTNASLLTCEVCKRNVLEKFGCFHIPCIAQNTRLHGPKRYAGHYVVLCGYDMAAQKLFYHNPEVHDGHICRCLIESMDTARRAYGTDEDIIFIYEKKETRE", "length": 240 }, "evidence": [ { "id": "A0A8V1A8C8", "url": "https://omabrowser.org/oma/group/A0A8V1A8C8/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 153, "end_pos": 155, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], 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"count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A8D3-1", "uniprot_ac": "A0A8V1A8D3", "uniprot_id": "A0A8V1A8D3_CHICK", "mass": { "chemical_mass": 10116.0, "monoisotopic_mass": 10116.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Epidermal differentiation protein", "type": "recommended", "evidence": [ { "id": "A0A8V1A8D3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8D3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A8D3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8D3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8D3", "locus": {} } ], "crossref": [ { "id": "A0A8V1A8D3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A8D3", "database": "AlphaFoldDB", "categories": [] }, { "id": "A0A8V1A8D3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8D3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A8D3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8D3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MCSRQDKDQCHRQERSSCHSSEGCGGGRGGSGCHGSSGSMCHSSSGGFGCHRSSGSGCHGSSGSGCHGSSGGSGCHGSSGGSCHGKPQDCQQQIYQVSSKMK", "length": 102, "header": "tr|A0A8V1A8D3-1|A0A8V1A8D3_CHICK Isoform 1 of Epidermal differentiation protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1A8D3-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A8D3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8D3/entry#A0A8V1A8D3-1", "sequence": { "sequence": "MCSRQDKDQCHRQERSSCHSSEGCGGGRGGSGCHGSSGSMCHSSSGGFGCHRSSGSGCHGSSGSGCHGSSGGSGCHGSSGGSCHGKPQDCQQQIYQVSSKMK", "length": 102, "header": "tr|A0A8V1A8D3-1|A0A8V1A8D3_CHICK Isoform 1 of Epidermal differentiation protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1A8D3-1" }, "locus": { "chromosome": "25", "start_pos": 1691171, "end_pos": 1690866, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068683.1", "url": "https://www.ensembl.org/id/ENSGALT00010068683.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042212.1", "url": "https://www.ensembl.org/id/ENSGALP00010042212.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A8E1-1", "uniprot_ac": "A0A8V1A8E1", "uniprot_id": "A0A8V1A8E1_CHICK", "mass": { "chemical_mass": 69623.0, "monoisotopic_mass": 69623.0 }, "refseq": {}, "gene_names": [ { "name": "CSPG5", "type": "recommended", "evidence": [ { "id": "A0A8V1A8E1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8E1" } ] } ], "protein_names": [ { "name": "Chondroitin sulfate proteoglycan 5", "type": "synonym", "evidence": [ { "id": "A0A8V1A8E1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8E1/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A8E1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8E1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CSPG5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8E1", "locus": { "chromosome": "2", "start_pos": 896412, "end_pos": 890302, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027290", "url": "https://www.ensembl.org/id/ENSGALG00010027290" } ] } } ], "crossref": [ { "id": "A0A8V1A8E1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A8E1", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR009505", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009505", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010555", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010555", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A8E1", "url": "https://www.orthodb.org/?gene=A0A8V1A8E1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AB16", "url": "https://www.orthodb.org/?gene=A0A8V1AB16", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ADU4", "url": "https://www.orthodb.org/?gene=A0A8V1ADU4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15381", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15381", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15381:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15381:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06566", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06566", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF06567", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06567", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-1971475", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1971475", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-2022870", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2022870", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-2022923", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2022923", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-2024101", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2024101", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1A8E1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8E1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A8E1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8E1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AB16", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB16", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AB16-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB16-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ADU4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADU4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ADU4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADU4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MCMGGRIPLYACMGGLDPIICVYEGAASHYVYGGAGSRVLLRPLQALCPHGEGRSTPIATHGVLRGPRGTGGGSQSRAAIPMGVGGTSASDTALSLCPTAPEWPPRNGSSGRAWGGPLQSGAPINSTDPLGPQLEPPGGGPATADPTVGCMGCSGEGAASSVPPVPDAAQDPRLGVTGPTDGDGGVVALGSPEEVGSGEQPTRAGVGPTEGLTPRPPGLPSPGLGLSSPGPNLGLPSLDLPNPNLGLPDPNLGLPNPSLGLPSPGPTPDRPIPNPNPSLDLPDPGLAIQTPNLGLSNPNIPLPSPSPGPGTEPDLLPVAEDSEVSMELPQPSSSPAPAQRARGRTDRTWLGAPEPISAAPGTAEPPEIIDVDYYDVFDGGHGPGGGHGAGGAAQREPGGAATPWGLHELYDDFTPFDEADFYPTTSFYAEGDDDAEEELEEDEEEEEEEDGGLEDENGYRPPASAAPRVPPPPSPTEGTPMARPRPGERAVPENSSECRSGYVRHNSSCRSVCDLVPSYCHNGGQCYLVESHGAFCRCNTQDYTWHKGTRCEAIVTDFQVLCVAVGSAALVLLLLFMLTVFFAKKLYLLKTENSKLRKTKYRTPSELHNDNFSLSTIAEGSHPNDDPGAPHKLQDPLKPGLKDEEPLSILSTAPEEGSKGEPGGCGVPCLHNNLG", "length": 675, "header": "tr|A0A8V1A8E1-1|A0A8V1A8E1_CHICK Isoform 1 of Chondroitin sulfate proteoglycan 5 OS=Gallus gallus OX=9031 GN=CSPG5 PE=4 SV=1 CANONICAL=A0A8V1A8E1-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A8E1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8E1/entry#A0A8V1A8E1-1", "sequence": { "sequence": "MCMGGRIPLYACMGGLDPIICVYEGAASHYVYGGAGSRVLLRPLQALCPHGEGRSTPIATHGVLRGPRGTGGGSQSRAAIPMGVGGTSASDTALSLCPTAPEWPPRNGSSGRAWGGPLQSGAPINSTDPLGPQLEPPGGGPATADPTVGCMGCSGEGAASSVPPVPDAAQDPRLGVTGPTDGDGGVVALGSPEEVGSGEQPTRAGVGPTEGLTPRPPGLPSPGLGLSSPGPNLGLPSLDLPNPNLGLPDPNLGLPNPSLGLPSPGPTPDRPIPNPNPSLDLPDPGLAIQTPNLGLSNPNIPLPSPSPGPGTEPDLLPVAEDSEVSMELPQPSSSPAPAQRARGRTDRTWLGAPEPISAAPGTAEPPEIIDVDYYDVFDGGHGPGGGHGAGGAAQREPGGAATPWGLHELYDDFTPFDEADFYPTTSFYAEGDDDAEEELEEDEEEEEEEDGGLEDENGYRPPASAAPRVPPPPSPTEGTPMARPRPGERAVPENSSECRSGYVRHNSSCRSVCDLVPSYCHNGGQCYLVESHGAFCRCNTQDYTWHKGTRCEAIVTDFQVLCVAVGSAALVLLLLFMLTVFFAKKLYLLKTENSKLRKTKYRTPSELHNDNFSLSTIAEGSHPNDDPGAPHKLQDPLKPGLKDEEPLSILSTAPEEGSKGEPGGCGVPCLHNNLG", "length": 675, "header": "tr|A0A8V1A8E1-1|A0A8V1A8E1_CHICK Isoform 1 of Chondroitin sulfate proteoglycan 5 OS=Gallus gallus OX=9031 GN=CSPG5 PE=4 SV=1 CANONICAL=A0A8V1A8E1-1" }, "locus": { "chromosome": "2", "start_pos": 896152, "end_pos": 891284, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066169.1", "url": "https://www.ensembl.org/id/ENSGALT00010066169.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040436.1", "url": "https://www.ensembl.org/id/ENSGALP00010040436.1" } ] } }, { "isoform_ac": "A0A8V1AB16-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8E1/entry#A0A8V1AB16-1", "sequence": { "sequence": "MAPPAPPPRAALTLLLALSAIGPAAPAPEWPPRNGSSGRAWGGPLQSGAPINSTDPLGPQLEPPGGGPATADPTVGCMGCSGEGAASSVPPVPDAAQDPRLGVTGPTDGDGGVVALGSPEEVGSGEQPTRAGVGPTEGLTPRPPGLPSPGLGLSSPGPNLGLPSLDLPNPNLGLPDPNLGLPNPSLGLPSPGPTPDRPIPNPNPSLDLPDPGLAIQTPNLGLSNPNIPLPSPSPGPGTEPDLLPVAEDSEVSMELPQPSSSPAPAQRARGRTDRTWLGAPEPISAAPGTAEPPEIIDVDYYDVFDGGHGPGGGHGAGGAAQREPGGAATPWGLHELYDDFTPFDEADFYPTTSFYAEGDDDAEEELEEDEEEEEEEDGGLEDENGYRPPASAAPRVPPPPSPTEGTPMARPRPGERAVPENSSECRSGYVRHNSSCRSVCDLVPSYCHNGGQCYLVESHGAFCRCNTQDYTWHKGTRCEAIVTDFQVLCVAVGSAALVLLLLFMLTVFFAKKLYLLKTENSKLRKTKYRTPSELHNDNFSLSTIAEGSHPNREAQHRAL", "length": 559, "header": "tr|A0A8V1AB16-1|A0A8V1AB16_CHICK Computationally mapped isoform of Chondroitin sulfate proteoglycan 5 OS=Gallus gallus OX=9031 GN=CSPG5 PE=4 SV=1 CANONICAL=A0A8V1A8E1-1" }, "locus": { "chromosome": "2", "start_pos": 894817, "end_pos": 890302, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066167.1", "url": "https://www.ensembl.org/id/ENSGALT00010066167.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040433.1", "url": "https://www.ensembl.org/id/ENSGALP00010040433.1" } ] } }, { "isoform_ac": "A0A8V1ADU4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8E1/entry#A0A8V1ADU4-1", "sequence": { "sequence": "MDRIGTDRIHLQGPAPEWPPRNGSSGRAWGGPLQSGAPINSTDPLGPQLEPPGGGPATADPTVGCMGCSGEGAASSVPPVPDAAQDPRLGVTGPTDGDGGVVALGSPEEVGSGEQPTRAGVGPTEGLTPRPPGLPSPGLGLSSPGPNLGLPSLDLPNPNLGLPDPNLGLPNPSLGLPSPGPTPDRPIPNPNPSLDLPDPGLAIQTPNLGLSNPNIPLPSPSPGPGTEPDLLPVAEDSEVSMELPQPSSSPAPAQRARGRTDRTWLGAPEPISAAPGTAEPPEIIDVDYYDVFDGGHGPGGGHGAGGAAQREPGGAATPWGLHELYDDFTPFDEADFYPTTSFYAEGDDDAEEELEEDEEEEEEEDGGLEDENGYRPPASAAPRVPPPPSPTEGTPMARPRPGERAVPENSSECRSGYVRHNSSCRSVCDLVPSYCHNGGQCYLVESHGAFCRCNTQDYTWHKGTRCEAIVTDFQVLCVAVGSAALVLLLLFMLTVFFAKKLYLLKTENSKLRKTKYRTPSELHNDNFSLSTIAEGSHPNDDPGAPHKLQDPLKPGLKDEEPLSILSTAPEEGSKGEPGGCGVPCLHNNLG", "length": 590, "header": "tr|A0A8V1ADU4-1|A0A8V1ADU4_CHICK Computationally mapped isoform of Chondroitin sulfate proteoglycan 5 OS=Gallus gallus OX=9031 GN=CSPG5 PE=4 SV=1 CANONICAL=A0A8V1A8E1-1" }, "locus": { "chromosome": "2", "start_pos": 896152, "end_pos": 890873, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066171.1", "url": 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}, "locus": { "chromosome": "12", "start_pos": 9772329, "end_pos": 9746408, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068822.1", "url": "https://www.ensembl.org/id/ENSGALT00010068822.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042264.1", "url": "https://www.ensembl.org/id/ENSGALP00010042264.1" } ] } }, { "isoform_ac": "A0A8V1AG76-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8I4/entry#A0A8V1AG76-1", "sequence": { "sequence": "MDHRTEERRKQRHSLTLLEQVKRMKESSEIVDVVLVAEGQKFPCHKVVLAAFSSYFKAMFTCGLVECTQREVVLYDISAESVSVILNYIYSADLHLTNQNVQTVALASYFMQMEDVFSLCQKYMMDHMDASNCVGIYYFANHIGAEDLCDQAKRYLYQHFAEVSLQEEILEIEVQQLLALIKSDDLNVSREESILDLVIRWVNHSRKSRAEHLIKLLKEVRLMDLPDDEPDRLSNRMFQYDPGRDKWTERAPMKYSKYRFSTAVVNSEIYVLGGIGCLGRDRGQTRKCLDAVEIYNPDGDFWRDGPPMPSPLLSLRTNSTCAGCVEGKLYLCGGFHGAARHEVITKEILELDTWENQWNVVAINVLMHDSYDVCLVARLNPRDLIPPPPDLVDQ", "length": 394, "header": "tr|A0A8V1AG76-1|A0A8V1A8I4_CHICK Computationally mapped isoform of Kelch repeat and BTB domain containing 12 OS=Gallus gallus OX=9031 GN=KBTBD12 PE=4 SV=1 CANONICAL=A0A8V1A8I4-1" }, "locus": { "chromosome": "12", "start_pos": 9772329, "end_pos": 9746408, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068821.1", "url": "https://www.ensembl.org/id/ENSGALT00010068821.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042263.1", "url": "https://www.ensembl.org/id/ENSGALP00010042263.1" } ] } }, { "isoform_ac": "A0A8V1AKB6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8I4/entry#A0A8V1AKB6-1", "sequence": { "sequence": "MDHRTEERRKQRHSLTLLEQVKRMKESSEIVDVVLVAEGQKFPCHKVVLAAFSSYFKAMFTCGLVECTQREVVLYDISAESVSVILNYIYSADLHLTNQNVQTVALASYFMQMEDVFSLCQKYMMDHMDASNCVGIYYFANHIGAEDLCDQAKRYLYQHFAEVSLQEEILEIEVQQLLALIKSDDLNVSREESILDLVIRWVNHSRKSRAEHLIKLLKEVRLVLVSPSFLMEARKRNTVILCNSECNDMFEEALKSIRLATHPSLSLRYGMETTDLLLCIGNNSLGIRSRHGSYADASFCYAPATQKTYFISSPKYGEGLGSVCSGVVTENNDIIVAGEASAAKMSRQKNRNIEIYRKTKQGEKELYPYLIILTENTNFKKGSSFMKTCSMDLPDDEPDRLSNRMFQYDPGRDKWTERAPMKYSKYRFSTAVVNSEIYVLGGIGCLGRDRGQTRKCLDAVEIYNPDGDFWRDGPPMPSPLLSLRTNSTCAGCVEGKLYLCGGFHGAARHEVITKEILELDTWENQWNVVAINVLMHDSYDVCLVARLNPRDLIPPPPDLVDQ", "length": 562, "header": "tr|A0A8V1AKB6-1|A0A8V1A8I4_CHICK Computationally mapped isoform of Kelch repeat and BTB domain containing 12 OS=Gallus gallus OX=9031 GN=KBTBD12 PE=4 SV=1 CANONICAL=A0A8V1A8I4-1" }, "locus": { "chromosome": "12", "start_pos": 9772329, "end_pos": 9746408, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068823.1", "url": "https://www.ensembl.org/id/ENSGALT00010068823.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042265.1", "url": "https://www.ensembl.org/id/ENSGALP00010042265.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A8I4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8I4" } ], "pmid": "" }, { "name": "Cul3-RING ubiquitin ligase complex", "id": "GO:0031463", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031463", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A8I4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8I4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": 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:: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052556.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015154144.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015154144", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015154144" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A8K8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8K8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "DAP3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8K8", "locus": { "chromosome": "25", "start_pos": 2176696, "end_pos": 2168339, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028425", "url": "https://www.ensembl.org/id/ENSGALG00010028425" } ] } } ], "crossref": [ { "id": "A0A8V1A8K8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A8K8", "database": "AlphaFoldDB", "categories": [] }, { "id": "425065", "url": 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"MLRSVKGFICRPLKLDHGYALHMAAKDCFSSVVSQDVQTPAEKPRAIFYTNESDPAQHSEQHEGRHYSIPLEEVKAVFPHGLPYRFQQQIKTFQEACVMVRKPALELFTYLKNSNFAHPVVRYVIYGERGTGKTMTLCHVVHFCARQGWLVLHIPDAHLWVKNCKELMQSSYNKERLDQPLQASFWLRNFRTTNEHFLKEIKTQQKYVWGKRDSTEQGRPLGEVVEQGLTRVKNASDAVGVVLKEIKQQCCLGSFRVLVAVDGVNALWGRTTLKKEDKSPVSPEELTLVYNLRKMVMNNWSGGAVVTTLSQTGSLFKPSSAHLPHELLGKEGFDALDPFVPILVPNYTEREFESCYHYYLHCRWLQHEKARTEDGKEELRFLSGCNPWQLERLSAPL", "length": 397, "header": "tr|A0A8V1A8K8-1|A0A8V1A8K8_CHICK Isoform 1 of Small ribosomal subunit protein mS29 OS=Gallus gallus OX=9031 GN=DAP3 PE=1 SV=1 CANONICAL=A0A8V1A8K8-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A8K8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8K8/entry#A0A8V1A8K8-1", "sequence": { "sequence": "MLRSVKGFICRPLKLDHGYALHMAAKDCFSSVVSQDVQTPAEKPRAIFYTNESDPAQHSEQHEGRHYSIPLEEVKAVFPHGLPYRFQQQIKTFQEACVMVRKPALELFTYLKNSNFAHPVVRYVIYGERGTGKTMTLCHVVHFCARQGWLVLHIPDAHLWVKNCKELMQSSYNKERLDQPLQASFWLRNFRTTNEHFLKEIKTQQKYVWGKRDSTEQGRPLGEVVEQGLTRVKNASDAVGVVLKEIKQQCCLGSFRVLVAVDGVNALWGRTTLKKEDKSPVSPEELTLVYNLRKMVMNNWSGGAVVTTLSQTGSLFKPSSAHLPHELLGKEGFDALDPFVPILVPNYTEREFESCYHYYLHCRWLQHEKARTEDGKEELRFLSGCNPWQLERLSAPL", "length": 397, "header": "tr|A0A8V1A8K8-1|A0A8V1A8K8_CHICK Isoform 1 of Small ribosomal subunit protein mS29 OS=Gallus gallus OX=9031 GN=DAP3 PE=1 SV=1 CANONICAL=A0A8V1A8K8-1" }, "locus": { "chromosome": "25", "start_pos": 2176672, "end_pos": 2169114, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068848.1", "url": "https://www.ensembl.org/id/ENSGALT00010068848.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042290.1", "url": "https://www.ensembl.org/id/ENSGALP00010042290.1" } ] } }, { "isoform_ac": "A0A8V1ADP8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8K8/entry#A0A8V1ADP8-1", "sequence": { "sequence": "MRKLNPSPFPADKMLRSVKGFICRPLKLDHGYALHMAAKDCFSSVVSQDVQTPAEKPRAIFYTNESDPAQHSEQHEGRHYSIPLEEVKAVFPHGLPYRFQQQIKTFQEACVMVRKPALELFTYLKNSNFAHPVVRYVIYGERGTGKTMTLCHVVHFCARQGWLVLHIPDAHLWVKNCKELMQSSYNKERLDQPLQASFWLRNFRTTNEHFLKEIKTQQKYVWGKRDSTEQGRPLGEVVEQGLTRVKNASDAVGVVLKEIKQQCCLGSFRVLVAVDGVNALWGRTTLKKEDKSPVSPEELTLVYNLRKMVMNNWSGGAVVTTLSQTGSLFKPSSAHLPHELLGKEGFDALDPFVPILVPNYTEREFESCYHYYLHCRWLQHEKARTEDGKEELRFLSGCNPWQLERLSAPL", "length": 410, "header": "tr|A0A8V1ADP8-1|A0A8V1ADP8_CHICK Computationally mapped isoform of Small ribosomal subunit protein mS29 OS=Gallus gallus OX=9031 GN=DAP3 PE=1 SV=1 CANONICAL=A0A8V1A8K8-1" }, "locus": { "chromosome": "25", "start_pos": 2176672, "end_pos": 2169075, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068850.1", "url": "https://www.ensembl.org/id/ENSGALT00010068850.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042292.1", "url": "https://www.ensembl.org/id/ENSGALP00010042292.1" } ] } }, { "isoform_ac": "A0A8V1AIJ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8K8/entry#A0A8V1AIJ5-1", "sequence": { "sequence": "MLRSVKGFICRPLKLDHGYALHMAAKDCFSSVVSQDVQTPAEKPRAIFYTNESDPAQHSEQHEGRHYSIPLEEVKAVFPHGLPYRFQQQIKTFQEACVMVRKPALELFTYLKNSNFAHPVVRYVIYGERGTGKTMTLCHVVHFCARQGWLVLHIPDAHLWVKNCKELMQSSYNKERLDQPLQASFWLRNFRTTNEHFLKEIKTQQKYVWGKRDSTEQGRPLGEVVEQGLTRVKNASDAVGVVLKEIKQQCCLGSFRVLVAVDGVNALWGRTTLKKEDKSPVSPEELTLVYNLRKMVMNNWLQCSILELRCLRGAMDTLSGSRAHFTVCSAPISERWCCGDNAQPDRFPLQAQLCPSAPRAAGKGGVRCTGSLCPHPRAQLHRA", "length": 383, "header": "tr|A0A8V1AIJ5-1|A0A8V1A8K8_CHICK Computationally mapped isoform of Small ribosomal subunit protein mS29 OS=Gallus gallus OX=9031 GN=DAP3 PE=1 SV=1 CANONICAL=A0A8V1A8K8-1" }, "locus": { "chromosome": "25", "start_pos": 2176447, "end_pos": 2169114, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068851.1", "url": "https://www.ensembl.org/id/ENSGALT00010068851.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042293.1", "url": "https://www.ensembl.org/id/ENSGALP00010042293.1" } ] } }, { "isoform_ac": "A0A8V1AKD4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8K8/entry#A0A8V1AKD4-1", "sequence": { "sequence": "MLRSVKGFICRPLKLDHGYALHMAAKDCFSSVVSQDVQTPAEKPRAIFYTNESDPIKTFQEACVMVRKPALELFTYLKNSNFAHPVVRYVIYGERGTGKTMTLCHVVHFCARQGWLVLHIPDAHLWVKNCKELMQSSYNKERLDQPLQASFWLRNFRTTNEHFLKEIKTQQKYVWGKRDSTEQGRPLGEVVEQGLTRVKNASDAVGVVLKEIKQQCCLGSFRVLVAVDGVNALWGRTTLKKEDKSPVSPEELTLVYNLRKMVMNNWSGGAVVTTLSQTGSLFKPSSAHLPHELLGKEGFDALDPFVPILVPNYTEREFESCYHYYLHCRWLQHEKARTEDGKEELRFLSGCNPWQLERLSAPL", "length": 363, "header": "tr|A0A8V1AKD4-1|A0A8V1A8K8_CHICK Computationally mapped isoform of Small ribosomal subunit protein mS29 OS=Gallus gallus OX=9031 GN=DAP3 PE=1 SV=1 CANONICAL=A0A8V1A8K8-1" }, "locus": { "chromosome": "25", "start_pos": 2176672, "end_pos": 2169114, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068849.1", "url": "https://www.ensembl.org/id/ENSGALT00010068849.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042291.1", "url": "https://www.ensembl.org/id/ENSGALP00010042291.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:425065", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:425065", "resource": "KEGG Pathway" }, { "id": "R-GGA-5389840", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5389840", "resource": "Reactome", "description": "Mitochondrial translation elongation" }, { "id": "R-GGA-5419276", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5419276", "resource": "Reactome", "description": "Mitochondrial translation termination" }, { "id": "R-GGA-9937383", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9937383", "resource": "Reactome", "description": "Mitochondrial ribosome-associated quality control" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2K264-1", "protein_name": "Small ribosomal subunit protein mS29", "gene_name": "Dap3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRTKTMLTGMTRFFSRVQKLDPRCFLHVSVQAPQNNQVPAERPRAVSRTSDSDPAKHGEQHEGQHYSIPPQDLKTVFPHGLPPRYAMQVKTFGEACLMVRKPALELLGYLKNTNFAHPAVRYLLYGEKGTGKTLSLCHAVHFCAKSDWLILHIPDAHLWVKNCGELLQSTYNKQRFDQPLEASTWLKNFKTTNERFLGQIKVQEKYVWNKRESTEKGSPLGEVVEQGLTRVRNATDAVGVVLKELKTQSSLGLFHLLVAVDGVNALWGRTTLKREDRTLIAPEELALVRNLRKMVKNDWHGGAIVLSLSQTGSLFKSRTAYLPHELLGKEGFNALEPFLPILISNYNPKEFESSFQYYLENNWLQHEKGSISLCTHAYLRYPSLLSSAHPATQGLRSSFLSRPDLMACIANI", "length": 412 }, "evidence": [ { "id": "A0A8V1A8K8", "url": "https://omabrowser.org/oma/group/A0A8V1A8K8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P51398-1", "protein_name": "Small ribosomal subunit protein mS29", "gene_name": "DAP3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MMLKGITRLISRIHKLDPGRFLHMGTQARQSIAAHLDNQVPVESPRAISRTNENDPAKHGDQHEGQHYNISPQDLETVFPHGLPPRFVMQVKTFSEACLMVRKPALELLHYLKNTSFAYPAIRYLLYGEKGTGKTLSLCHVIHFCAKQDWLILHIPDAHLWVKNCRDLLQSSYNKQRFDQPLEASTWLKNFKTTNERFLNQIKVQEKYVWNKRESTEKGSPLGEVVEQGITRVRNATDAVGIVLKELKRQSSLGMFHLLVAVDGINALWGRTTLKREDKSPIAPEELALVHNLRKMMKNDWHGGAIVSALSQTGSLFKPRKAYLPQELLGKEGFDALDPFIPILVSNYNPKEFESCIQYYLENNWLQHEKAPTEEGKKELLFLSNANPSLLERHCAYL", "length": 398 }, "evidence": [ { "id": "A0A8V1A8K8", "url": "https://omabrowser.org/oma/group/A0A8V1A8K8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9ER88-1", "protein_name": "Small ribosomal subunit protein mS29", "gene_name": "Dap3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLTGITRLFSRVQKLDPRCFLHMSVQATQNSQVPAERPRTVSRTSDSDPAKHGEQHEGQHYSIPLQDLKTVFPHGLPPRYMMQVKTFGEACLMVRKPALELLGYLKNTNFAHPAVRYLLYGEKGTGKTLSLCHAVHFCARHDWLILHIPDAHLWVKNCRELLQSTHNKQRFDQPLEASTWLKNFKTTNERFLSQIKVQEKYVWNKRESTEKGSPLGEVVEQGLTRVRNATDAVGVVLKELKAQSALGLFHLLVAVDGVNALWGRTTLKKEDRTLIAPEELSLVHNLRKMVKNDWHGGAIVLSLSQTGSLFKSRTAYLPHELLGKEGFNALEPFLPILIPNYNPKEFESSFQYYLENNWLQHEKASTEEGRKELRFLSNCNPEQLERLCASL", "length": 391 }, "evidence": [ { "id": "A0A8V1A8K8", "url": "https://omabrowser.org/oma/group/A0A8V1A8K8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9W253-1", "protein_name": "Small ribosomal subunit protein mS29", "gene_name": "mRpS29", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MKMIRNRFGSLSRVSAQLQRHVQQMSTNAAASPAEGATISEFRTAVSNPGEHSAMQVAKFYTIPAEQKKQIFTGGGLPKQYEQQIKTFTEACLMVRNPALELLQYIKDGDLTKPVVRYVLYGENGTGKTLTMAHVLHYGALNDFLLVHVPWAPNWMKRPKEASNAAGQEGMIDLPFDAAAWLVHFKTQNGPLLQRLQLKTSKEYVWSKRESTPAGSSLIELVEHGIARIKYASETTAALIAELKQLSTAGQCKVMVAIDGFNAFFHPVTRIFSDNKQLVTPDRVTLTQPFLDITNYDWTNGVCILSVDKIAMTEGHMDSYMPRYLLGKEGFEHLDPFVPIHVENYTDKEFHSYISYYLDRHWINKTPQGFEEQLKFMSNKNPYSLMQLVKAL", "length": 392 }, "evidence": [ { "id": "A0A8V1A8K8", "url": "https://omabrowser.org/oma/group/A0A8V1A8K8/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A8K8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8K8" } ], "pmid": "" }, { "name": "mitochondrial translation", "id": "GO:0032543", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032543", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A8K8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8K8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "mitochondrial ribosome", "id": "GO:0005761", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005761", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A8K8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8K8" } ], "pmid": "" }, { "name": "small ribosomal subunit", "id": "GO:0015935", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015935", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A8K8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8K8" } ], "pmid": "" }, { "name": "mitochondrial small ribosomal subunit", "id": "GO:0005763", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005763", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A8K8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8K8" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A8K8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8K8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A8K8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8K8" } ], "pmid": "" }, { "name": "structural constituent of ribosome", "id": "GO:0003735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003735", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A8K8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8K8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 234, "end_pos": 236, "annotation": "n_glycosylation_sequon" }, { "start_pos": 299, "end_pos": 301, "annotation": "n_glycosylation_sequon" }, { "start_pos": 346, "end_pos": 348, "annotation": "n_glycosylation_sequon" }, { "start_pos": 51, "end_pos": 53, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 234, "end_pos": 236 }, { "start_pos": 299, "end_pos": 301 }, { "start_pos": 346, "end_pos": 348 }, { "start_pos": 51, "end_pos": 53 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A8L3-1", "uniprot_ac": "A0A8V1A8L3", "uniprot_id": "A0A8V1A8L3_CHICK", "mass": { "chemical_mass": 31748.0, "monoisotopic_mass": 31748.0 }, "refseq": {}, "gene_names": [ { "name": "S100A16", "type": "recommended", "evidence": [ { "id": "A0A8V1A8L3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8L3" } ] } ], "protein_names": [ { "name": "S100 calcium binding protein A16", "type": "synonym", "evidence": [ { "id": "A0A8V1A8L3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8L3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A8L3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8L3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "S100A16", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8L3", "locus": {} } ], "crossref": [ { "id": "A0A8V1A8L3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A8L3", "database": "AlphaFoldDB", "categories": [] }, { "id": "100859094", "url": "https://www.ncbi.nlm.nih.gov/gene/100859094", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001751", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001751", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002048", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002048", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013787", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013787", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018247", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018247", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:100859094", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100859094", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DCYTDLE", "url": "https://omabrowser.org/oma/group/DCYTDLE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR11639", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11639", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11639:SF76", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11639:SF76", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01023", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01023", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1A8L3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8L3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A8L3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8L3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGA0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGA0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGA0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGA0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGSGLRAGVTGRGRKRGEERRGGGGRKVGTCAPQCCCRLWVGDTRPRGAHSTIESILFVAQRGYSVPTHGVGAGGIQQLCTHGRGRAARILPPLGRAVLPSLPRWPFASEPLAAEGNSAWRQCCPPPRASCTLLASTFGSLIPAASSARGFRSSFAAKQCPNGGDPETLGEIFCTSVGPAALPASVNVGAMAEGTELEWAVQVLVNNFDKYSSRCCCRKPRRISKKDFRKMLSRELNHMLTDTGNRRAADKLICDLDENKDGRISFEEYWTLIGGIASPIAHIIRQQEQSVKLTK", "length": 295, "header": "tr|A0A8V1A8L3-1|A0A8V1A8L3_CHICK Isoform 1 of S100 calcium binding protein A16 OS=Gallus gallus OX=9031 GN=S100A16 PE=3 SV=1 CANONICAL=A0A8V1A8L3-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A8L3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8L3/entry#A0A8V1A8L3-1", "sequence": { "sequence": "MGSGLRAGVTGRGRKRGEERRGGGGRKVGTCAPQCCCRLWVGDTRPRGAHSTIESILFVAQRGYSVPTHGVGAGGIQQLCTHGRGRAARILPPLGRAVLPSLPRWPFASEPLAAEGNSAWRQCCPPPRASCTLLASTFGSLIPAASSARGFRSSFAAKQCPNGGDPETLGEIFCTSVGPAALPASVNVGAMAEGTELEWAVQVLVNNFDKYSSRCCCRKPRRISKKDFRKMLSRELNHMLTDTGNRRAADKLICDLDENKDGRISFEEYWTLIGGIASPIAHIIRQQEQSVKLTK", "length": 295, "header": "tr|A0A8V1A8L3-1|A0A8V1A8L3_CHICK Isoform 1 of S100 calcium binding protein A16 OS=Gallus gallus OX=9031 GN=S100A16 PE=3 SV=1 CANONICAL=A0A8V1A8L3-1" }, "locus": { "chromosome": "25", "start_pos": 1728365, "end_pos": 1725624, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068853.1", "url": "https://www.ensembl.org/id/ENSGALT00010068853.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042295.1", "url": "https://www.ensembl.org/id/ENSGALP00010042295.1" } ] } }, { "isoform_ac": "A0A8V1AGA0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8L3/entry#A0A8V1AGA0-1", "sequence": { "sequence": "MAEGTELEWAVQVLVNNFDKYSSRCCCRKPRRISKKDFRKMLSRELNHMLTDTGNRRAADKLICDLDENKDGRISFEEYWTLIGGIASPIAHIIRQQEQSVKLTK", "length": 105, "header": "tr|A0A8V1AGA0-1|A0A8V1A8L3_CHICK Computationally mapped isoform of S100 calcium binding protein A16 OS=Gallus gallus OX=9031 GN=S100A16 PE=3 SV=1 CANONICAL=A0A8V1A8L3-1" }, "locus": { "chromosome": "25", "start_pos": 1726028, "end_pos": 1725624, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068852.1", "url": "https://www.ensembl.org/id/ENSGALT00010068852.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042294.1", "url": "https://www.ensembl.org/id/ENSGALP00010042294.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:100859094", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100859094", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F2Z5M4-1", "protein_name": "Protein S100", "gene_name": "S100A16", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MADSYTELEKAVVVLVENFYKYVSKHSLVKNKISKSSFRKMLQKELNHMLTDTGNRKAADKLIQNLDANHDGRISFDEYWTLIGGITSPIANLIRQQEQQSSS", "length": 103 }, "evidence": [ { "id": "A0A8V1A8L3", "url": "https://omabrowser.org/oma/group/A0A8V1A8L3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3HC27-1", "protein_name": "Protein S100", "gene_name": "S100a16", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MADCYTELEKAVVVLVENFYKYVSKHSLVKNKISKSSFRKMLQRELNHMLTDTGNRKAADKLIQNLDANHDGRISFDEYWTMIGGITSPMANLIRQQECQQEQQGSS", "length": 107 }, "evidence": [ { "id": "A0A8V1A8L3", "url": "https://omabrowser.org/oma/group/A0A8V1A8L3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q0VCM0-1", "protein_name": "Protein S100-A16", "gene_name": "S100A16", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MADSYTELEKAVVVLVENFYKYVSKHSLVKNKISKSSFRKMLQKELNHMLTDTGNRKAADKLIQNLDANHDGRISFDEYWTLIGGITSPIANLIRQQEQQSSS", "length": 103 }, "evidence": [ { "id": "A0A8V1A8L3", "url": "https://omabrowser.org/oma/group/A0A8V1A8L3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q96FQ6-1", "protein_name": "Protein S100-A16", "gene_name": "S100A16", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSDCYTELEKAVIVLVENFYKYVSKYSLVKNKISKSSFREMLQKELNHMLSDTGNRKAADKLIQNLDANHDGRISFDEYWTLIGGITGPIAKLIHEQEQQSSS", "length": 103 }, "evidence": [ { "id": "A0A8V1A8L3", "url": "https://omabrowser.org/oma/group/A0A8V1A8L3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9D708-1", "protein_name": "Protein S100-A16", "gene_name": "S100a16", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADCYTELEKAVVVLVENFYKYVSKHSLVKNKISKSSFRKMLQRELNHMLTDTGNRKAADKLIQNLDANHDGRICFDEYWTMIGGITSPMANLIRQQECQQESQQECQQESQQESQQESQQGSS", "length": 124 }, "evidence": [ { "id": "A0A8V1A8L3", "url": "https://omabrowser.org/oma/group/A0A8V1A8L3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A8L3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8L3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1A8L3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8L3" }, { "id": "PS50222", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50222" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EF-hand", "eco_id": "ECO_0000259", "start_pos": 244, "end_pos": 279, "start_aa": "Gly", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A8L7-1", "uniprot_ac": "A0A8V1A8L7", "uniprot_id": "A0A8V1A8L7_CHICK", "mass": { "chemical_mass": 60125.0, "monoisotopic_mass": 60125.0 }, "refseq": { "ac": "XP_418528", "name": "solute carrier family 22 member 13-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418528" }, "gene_names": [ { "name": "SLC22A13L", "type": "recommended", "evidence": [ { "id": "A0A8V1A8L7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8L7" } ] }, { "name": "SLC22A13L", "type": "synonym", "evidence": [ { "id": "XP_418528", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418528" } ] } ], "protein_names": [ { "name": "Major facilitator superfamily (MFS) profile domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8V1A8L7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8L7/entry#names_and_taxonomy" } ] }, { "name": "solute carrier family 22 member 13-like", "type": "synonym", "evidence": [ { "id": "XP_418528", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418528" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052533.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_418528.5. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_418528", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418528" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A8L7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8L7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SLC22A13L", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8L7", "locus": {} } ], "crossref": [ { "id": "A0A8V1A8L7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A8L7", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd17374", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17374", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "420422", "url": "https://www.ncbi.nlm.nih.gov/gene/420422", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR005828", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005828", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020846", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020846", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036259", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036259", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:420422", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420422", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WTSIPTI", "url": "https://omabrowser.org/oma/group/WTSIPTI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A8L7", "url": "https://www.orthodb.org/?gene=A0A8V1A8L7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24064", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24064", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00083", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00083", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_418528", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418528", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1A8L7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8L7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A8L7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8L7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSGIGENLKAAGEFGPFQRRLVLFSLPPCLILAFHQFCQLFMVVDVPHYCNTDWIRAVGPNLTEEEQLNLTVPRDADGEYEQCSMYSPVDWDLDSIMAYGLNATEKCSSGWVYPTALQPSLLTEFDLVCDRKNLNDVSQSIYMLGMFLGAMIFGLLSDRFGRRPVLLISILLEGLFGVGIALVPHFYVYLAFRCVVGASVSGIMMTLLALATEWVGVSYRPQAVLLSHCCFAAGQMILAGLSYGIPNWRLLQIVGSAPIFILFLFIWVLPESARWLVTKGKIEEAKKYLKKAASINKRTIPPELLDQLKCETQTKSGSILDLLRKKHLLKVTLIMSCAWFVNSLVYYGLSLNVTNFGLDIYLTQLAFGAVEIPGRVGCILMLQWFGRKKSQGGFLLLSGLVCLIITVIPEDQPVVITVLATIGKFTASASFSSAYVYTAELFPTIIRQSGVGLCSMVARVAGIIAPLILLLEQHHRAIPMAIYGGTTVLGGLLCFLLPETRGVELADGTEGGQPTAVVHENDSSSSETGHVKVKDGGQVNENTKNTYF", "length": 548, "header": "tr|A0A8V1A8L7-1|A0A8V1A8L7_CHICK Isoform 1 of Major facilitator superfamily (MFS) profile domain-containing protein OS=Gallus gallus OX=9031 GN=SLC22A13L PE=4 SV=1 CANONICAL=A0A8V1A8L7-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A8L7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8L7/entry#A0A8V1A8L7-1", "sequence": { "sequence": "MSGIGENLKAAGEFGPFQRRLVLFSLPPCLILAFHQFCQLFMVVDVPHYCNTDWIRAVGPNLTEEEQLNLTVPRDADGEYEQCSMYSPVDWDLDSIMAYGLNATEKCSSGWVYPTALQPSLLTEFDLVCDRKNLNDVSQSIYMLGMFLGAMIFGLLSDRFGRRPVLLISILLEGLFGVGIALVPHFYVYLAFRCVVGASVSGIMMTLLALATEWVGVSYRPQAVLLSHCCFAAGQMILAGLSYGIPNWRLLQIVGSAPIFILFLFIWVLPESARWLVTKGKIEEAKKYLKKAASINKRTIPPELLDQLKCETQTKSGSILDLLRKKHLLKVTLIMSCAWFVNSLVYYGLSLNVTNFGLDIYLTQLAFGAVEIPGRVGCILMLQWFGRKKSQGGFLLLSGLVCLIITVIPEDQPVVITVLATIGKFTASASFSSAYVYTAELFPTIIRQSGVGLCSMVARVAGIIAPLILLLEQHHRAIPMAIYGGTTVLGGLLCFLLPETRGVELADGTEGGQPTAVVHENDSSSSETGHVKVKDGGQVNENTKNTYF", "length": 548, "header": "tr|A0A8V1A8L7-1|A0A8V1A8L7_CHICK Isoform 1 of Major facilitator superfamily (MFS) profile domain-containing protein OS=Gallus gallus OX=9031 GN=SLC22A13L PE=4 SV=1 CANONICAL=A0A8V1A8L7-1" }, "locus": { "chromosome": "2", "start_pos": 4949731, "end_pos": 4943942, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010064596.1", "url": "https://www.ensembl.org/id/ENSGALT00010064596.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039571.1", "url": "https://www.ensembl.org/id/ENSGALP00010039571.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:420422", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420422", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8M6YVM2-1", "protein_name": "Solute carrier family 22 member 13b isoform X1", "gene_name": "slc22a13b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MIDFTQILSSVGEFGAFQKRLLVAVCLPNIFTAFHMFGQVFTAISFPHYCNSSWILRQAPNLTEEKQLNLTVPLDSKGQYESCKMFTPVEMDIEDIEHYGINTTTSCIDGWVYKAPKDSSTLITEFDLVCENKVYSEASQSIYMAGLLVGALLFGPMADKYGRRFATLLSLFLQFLSGVGVAFSPNIYVYIALRFVVGTTISGISINTFVLGTEWCGSAKRALFTILSHCFFAIGLMLLSGVAYGIRNWRVLQLVLSAPVGLFFIYYWILPESARWLLTQGKLDSAKREILKAARINGRKVSENLLDKMEAENTAKSSTMIDLFRVGYLRKRALIMCYMWFVTSLVYYGVSLNVGNFGLDIYLTQLIFGMAEFPARLSCFPLIQRFGRRICQSVVLLLGGTACLIIPAIPAKYPIVVTVIAVIGKFSLAASFSIVYVYTAELYPTVVRQNGVGLNSMCARVAGILAPLIGLLDVYHHAIPMIIYGSLPFVGGALTFLLPETLNTDLQDHTDIPADESMTVTEVKLERWGRRRGWDRERSTSQDFKSGRL", "length": 549 }, "evidence": [ { "id": "A0A8V1A8L7", "url": "https://omabrowser.org/oma/group/A0A8V1A8L7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "D3Z8A7-1", "protein_name": "Solute carrier family 22 member 13-like 1", "gene_name": "Slc22a13l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAQFAQVMAEVGDFGPFQVRVTILMGIPNFLSAFFVFSQVFMVLDEAHHCSVSWVKNHTFNLSAAEQLAVSIPNDTAGRPESCLMFRPPPDSASLEDILSHRFNETQACDSGWDYPENRPPSLKNEFDLVCERENLKRTSQSVFMAGLLVGALVFGPVCDWIGRRASILLQVLLSGITGVATAFVPSFELYMVLCFFSAIAVAGYMMSTMILVSEWVGPSWRTRAMVLAQSNFALGLMALAGLAYGVRNWRLLQIIGTTPIFLLVFYFWVLPESPRWLLSQGRTEEAKQLVQKAALVNGRPLASELLNQLVPEKTGPSGNALDLFRHPQLRKVTLILIAVWFVDSLLYYGLGFQVGDFGLDIYLTQVIFGVVEVPARLSSIPMMEKLGRKWSQLCTLTLAGVMCVIIIFIPGDLPTVATALAVVGKFASSAAFTISYVYTAELLPTIIRQTGMGLVSIFSRVGGIITPLVMLLEQYHKAIPMLIFGSLPIGAGLLCALLPETRGQTLKDTLQDLEQGGPHGEHRLLGRTSVAGVCLAVFRSFTEEGRPSLNVGSILLAMALNSINK", "length": 566 }, "evidence": [ { "id": "A0A8V1A8L7", "url": "https://omabrowser.org/oma/group/A0A8V1A8L7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O64515-1", "protein_name": "Organic cation/carnitine transporter 2", "gene_name": "OCT2", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAEPTQPLLTDSNSSSPRSLDDTIESYIGSFGWAQFLQAALVSFSGVFDAQQTFISVFTDSEPTWHCTDSNSICHESISNICILPKTAWSWDYSPHVSVISEWGLQCAGSFVKGLPESSFFVGCLIGGLVLSTLADSSLGRKNMLFLSCLVMAISTMLTVFSPNIWVYAVLRFVNGFGRATIGTCALVLSTELVGKKWRGRVGIMSFFGFMLGFLSLPLMAYMNRGSSWRILYAWTSIPTIIYCVLVRFFVCESPRWLFVRGRREEAISILKRVASIPSTDVSSGGAISMSFSSLPFEEDEEKPSTNVNIFTTMKVLVEKRWALKRLSAVMAIAFGIGLVYYGMPLALSNLDFNIYLSAAFNALMDLPANLITLFLVDKLSRRNALIGFTALGGVSSVLIFALHNMRIGNHGALQLALELISYFSACSAFNMEMIYTIELFPTCVRNSAIAMARQALVLGGVFSPIMVAAGRKNAFWSFGLFGLAIGLLGLFAVGLPETRGSDLCDTMDEEECKDRRSKVAVNNVIA", "length": 527 }, "evidence": [ { "id": "A0A8V1A8L7", "url": "https://omabrowser.org/oma/group/A0A8V1A8L7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9Y226-1", "protein_name": "Solute carrier family 22 member 13", "gene_name": "SLC22A13", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAQFVQVLAEIGDFGRFQIQLLILLCVLNFLSPFYFFAHVFMVLDEPHHCAVAWVKNHTFNLSAAEQLVLSVPLDTAGHPEPCLMFRPPPANASLQDILSHRFNETQPCDMGWEYPENRLPSLKNEFNLVCDRKHLKDTTQSVFMAGLLVGTLMFGPLCDRIGRKATILAQLLLFTLIGLATAFVPSFELYMALRFAVATAVAGLSFSNVTLLTEWVGPSWRTQAVVLAQCNFSLGQMVLAGLAYGFRNWRLLQITGTAPGLLLFFYFWALPESARWLLTRGRMDEAIQLIQKAASVNRRKLSPELMNQLVPEKTGPSGNALDLFRHPQLRKVTLIIFCVWFVDSLGYYGLSLQVGDFGLDVYLTQLIFGAVEVPARCSSIFMMQRFGRKWSQLGTLVLGGLMCIIIIFIPADLPVVVTMLAVVGKMATAAAFTISYVYSAELFPTILRQTGMGLVGIFSRIGGILTPLVILLGEYHAALPMLIYGSLPIVAGLLCTLLPETHGQGLKDTLQDLELGPHPRSPKSVPSEKETEAKGRTSSPGVAFVSSTYF", "length": 551 }, "evidence": [ { "id": "A0A8V1A8L7", "url": "https://omabrowser.org/oma/group/A0A8V1A8L7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A8L7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8L7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "transmembrane transporter activity", "id": "GO:0022857", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022857", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A8L7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8L7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 102, "end_pos": 104, "annotation": "n_glycosylation_sequon" }, { "start_pos": 352, "end_pos": 354, "annotation": "n_glycosylation_sequon" }, { "start_pos": 521, "end_pos": 523, "annotation": "n_glycosylation_sequon" }, { "start_pos": 61, "end_pos": 63, "annotation": "n_glycosylation_sequon" }, { "start_pos": 69, "end_pos": 71, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1A8L7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8L7" }, { "id": "PS50850", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50850" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Major facilitator superfamily (MFS) profile", "eco_id": "ECO_0000259", "start_pos": 95, "end_pos": 502, "start_aa": "Ser", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 102, "end_pos": 104 }, { "start_pos": 352, "end_pos": 354 }, { "start_pos": 521, "end_pos": 523 }, { "start_pos": 61, "end_pos": 63 }, { "start_pos": 69, "end_pos": 71 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A8M8-1", "uniprot_ac": "A0A8V1A8M8", "uniprot_id": "A0A8V1A8M8_CHICK", "mass": { "chemical_mass": 189059.0, "monoisotopic_mass": 189059.0 }, "refseq": {}, "gene_names": [ { "name": "COL5A1", "type": "recommended", "evidence": [ { "id": "A0A8V1A8M8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8M8" } ] } ], "protein_names": [ { "name": "Collagen type V alpha 1 chain", "type": "synonym", "evidence": [ { "id": "A0A8V1A8M8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8M8/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A8M8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8M8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "COL5A1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8M8", "locus": { "chromosome": "17", "start_pos": 8170255, "end_pos": 8041836, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028434", "url": "https://www.ensembl.org/id/ENSGALG00010028434" } ] } } ], "crossref": [ { "id": "cd00110", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00110", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000885", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000885", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001791", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001791", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008160", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008160", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048287", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048287", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050149", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050149", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050938", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050938", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A8M8", "url": "https://www.orthodb.org/?gene=A0A8V1A8M8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ADR4", "url": "https://www.orthodb.org/?gene=A0A8V1ADR4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AGB2", "url": "https://www.orthodb.org/?gene=A0A8V1AGB2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AIK7", "url": "https://www.orthodb.org/?gene=A0A8V1AIK7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AKE8", "url": "https://www.orthodb.org/?gene=A0A8V1AKE8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24023", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24023", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24023:SF1082", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24023:SF1082", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24023:SF1089", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24023:SF1089", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24023:SF1095", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24023:SF1095", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR37456", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR37456", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR37456:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR37456:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01391", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01391", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01410", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01410", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02210", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02210", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-1650814", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1650814", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-2022090", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2022090", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1A8M8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8M8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A8M8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8M8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ADR4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADR4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ADR4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADR4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGB2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGB2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGB2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGB2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AIK7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIK7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AIK7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIK7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AKE8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKE8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AKE8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKE8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDTHTRWKRRSWIRNWQLHVALVLLGAAALGRAAEPADLLKVLDFHNLPDGITRTTGFCTSRRSSKEADVAYRVTKDAQLSAPTKQLYPASPFPEDFSILTTVKAKKGGQSFLISIYNEQGIQQIGVEMGRSPVFLYEDHTGKPGPEDYPLFRGINLADGKWHRVAISVQKKNVTLILDCKKKITKFLDRSDHPIIDVNGIIVFGTRILDEEVFEGDIQQLLIVADPRAAHDYCEHYSPDCDTAVPDAPQSQDPNQDEYYTDGEGEGDTYYYEYPYYEDVDEAVKPEAPTTKPAPPGVAAGERPETKQDYPSPTPSPEAGNPSRQTKGAAPVDDPLVDEYNYETINEEYFTPLPYEDINYNEEVDPQGGLTENAVEAELPTSTVITYNETDAAQGGDDLDKDFTEETIKEYDGNYYYYDRTVSPDIGPGMPANQDTIYEGIGGPRGEKGQKGEPAIIEPGMLVEGPPGPEGPAGLPGPPGPTGPVGLMGDPGERGPPGRPGLPGADGLPGPPGTMLMLPFRFSGGGDAGSKGPMVSAQEAQAQAILQQARLALRGPAGPMGLTGRPGPMGPPGSGGLKGEAGEMGPQGPRGIQGPPGPAGKPGRRGRAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGNRGEPGPHGPPGAPGEDGERGDDGEVGPRGLPGEPGPRGLLGPKGPPGPPGPPGVAGMDGQTGPKGNVGPQGEPGPPGQQGNPGAQGLPGPQGPIGPPGEKGPLGKPGLPGMPGADGPPGHPGKEGPPGEKGSQGPPGPQGPIGYPGPRGVKGADGVRGLKGTKGEKGEDGFPGFKGDMGIKGDRGEIGPPGPRGEDGPEGPKGRSGPNGDPGPLGPAGEKGKLGVPGLPGYPGRQGPKGSIGFPGFPGANGEKGTRGTPGKPGPRGQRGPTGPRGERGPRGSTGKPGPKGNSGGDGPPGPPGERGPPGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQGLPGLTGKEGTKGDPGPAGLPGKDGPPGLRGFPGERGLPGPIGSPGLKGNEGPPGPPGPAGSPGERGPAGSAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGIQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPAGADGEPGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPSGPPGADGPQGPAGGIGNPGAVGEKGEPGESGEPGLPGEVGLPGPKGERGEKGEAGPSGAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDGLRGIPGPVGEQGLPGSPGPDGPPGPLGPPGLPGLKGDSGPKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSAGPKGEQGITGPSGPIGPPGPPGLPGPPGPKGAKGSSGPTGPKGESGLPGPPGPPGPPGEVIQPLPIQSSKRTRRNIDASQLVDDGNADNYMDYADGMEEIFGSLNSLKLEIEQMKHPLGTQHNPARTCKDLQLCHPDFPDGEYWVDPNQGCSRDSFKVYCNFTAGGETCIFPDKKSEGARITSWPKENPGSWFSEFKRGKLVRCISVLSVFFNPCRILQSKMARWPKEQPSTWYSQYKRGSLLSYVDSDGNPIGVVQMTFLRLLSASAHQNITYNCYQSVAWHDATTDSYDKAIRFLGSNDEEMSYDNNPYIRAAFDGCAAKKGYQKTVLEINTPKVEQVPIVDIMFNDFGEASQKFGFEVGPACFMG", "length": 1876, "header": "tr|A0A8V1A8M8-1|A0A8V1A8M8_CHICK Isoform 1 of Collagen type V alpha 1 chain OS=Gallus gallus OX=9031 GN=COL5A1 PE=1 SV=1 CANONICAL=A0A8V1A8M8-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A8M8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8M8/entry#A0A8V1A8M8-1", "sequence": { "sequence": "MDTHTRWKRRSWIRNWQLHVALVLLGAAALGRAAEPADLLKVLDFHNLPDGITRTTGFCTSRRSSKEADVAYRVTKDAQLSAPTKQLYPASPFPEDFSILTTVKAKKGGQSFLISIYNEQGIQQIGVEMGRSPVFLYEDHTGKPGPEDYPLFRGINLADGKWHRVAISVQKKNVTLILDCKKKITKFLDRSDHPIIDVNGIIVFGTRILDEEVFEGDIQQLLIVADPRAAHDYCEHYSPDCDTAVPDAPQSQDPNQDEYYTDGEGEGDTYYYEYPYYEDVDEAVKPEAPTTKPAPPGVAAGERPETKQDYPSPTPSPEAGNPSRQTKGAAPVDDPLVDEYNYETINEEYFTPLPYEDINYNEEVDPQGGLTENAVEAELPTSTVITYNETDAAQGGDDLDKDFTEETIKEYDGNYYYYDRTVSPDIGPGMPANQDTIYEGIGGPRGEKGQKGEPAIIEPGMLVEGPPGPEGPAGLPGPPGPTGPVGLMGDPGERGPPGRPGLPGADGLPGPPGTMLMLPFRFSGGGDAGSKGPMVSAQEAQAQAILQQARLALRGPAGPMGLTGRPGPMGPPGSGGLKGEAGEMGPQGPRGIQGPPGPAGKPGRRGRAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGNRGEPGPHGPPGAPGEDGERGDDGEVGPRGLPGEPGPRGLLGPKGPPGPPGPPGVAGMDGQTGPKGNVGPQGEPGPPGQQGNPGAQGLPGPQGPIGPPGEKGPLGKPGLPGMPGADGPPGHPGKEGPPGEKGSQGPPGPQGPIGYPGPRGVKGADGVRGLKGTKGEKGEDGFPGFKGDMGIKGDRGEIGPPGPRGEDGPEGPKGRSGPNGDPGPLGPAGEKGKLGVPGLPGYPGRQGPKGSIGFPGFPGANGEKGTRGTPGKPGPRGQRGPTGPRGERGPRGSTGKPGPKGNSGGDGPPGPPGERGPPGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQGLPGLTGKEGTKGDPGPAGLPGKDGPPGLRGFPGERGLPGPIGSPGLKGNEGPPGPPGPAGSPGERGPAGSAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGIQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPAGADGEPGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPSGPPGADGPQGPAGGIGNPGAVGEKGEPGESGEPGLPGEVGLPGPKGERGEKGEAGPSGAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDGLRGIPGPVGEQGLPGSPGPDGPPGPLGPPGLPGLKGDSGPKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSAGPKGEQGITGPSGPIGPPGPPGLPGPPGPKGAKGSSGPTGPKGESGLPGPPGPPGPPGEVIQPLPIQSSKRTRRNIDASQLVDDGNADNYMDYADGMEEIFGSLNSLKLEIEQMKHPLGTQHNPARTCKDLQLCHPDFPDGEYWVDPNQGCSRDSFKVYCNFTAGGETCIFPDKKSEGARITSWPKENPGSWFSEFKRGKLVRCISVLSVFFNPCRILQSKMARWPKEQPSTWYSQYKRGSLLSYVDSDGNPIGVVQMTFLRLLSASAHQNITYNCYQSVAWHDATTDSYDKAIRFLGSNDEEMSYDNNPYIRAAFDGCAAKKGYQKTVLEINTPKVEQVPIVDIMFNDFGEASQKFGFEVGPACFMG", "length": 1876, "header": "tr|A0A8V1A8M8-1|A0A8V1A8M8_CHICK Isoform 1 of Collagen type V alpha 1 chain OS=Gallus gallus OX=9031 GN=COL5A1 PE=1 SV=1 CANONICAL=A0A8V1A8M8-1" }, "locus": { "chromosome": "17", "start_pos": 8167503, "end_pos": 8042107, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068868.1", "url": "https://www.ensembl.org/id/ENSGALT00010068868.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042310.1", "url": "https://www.ensembl.org/id/ENSGALP00010042310.1" } ] } }, { "isoform_ac": "A0A8V1ADR4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8M8/entry#A0A8V1ADR4-1", "sequence": { "sequence": "MDTHTRWKRRSWIRNWQLHVALVLLGAAALGRAAEPADLLKVLDFHNLPDGITRTTGFCTSRRSSKEADVAYRVTKDAQLSAPTKQLYPASPFPEDFSILTTVKAKKGGQSFLISIYNEQGIQQIGVEMGRSPVFLYEDHTGKPGPEDYPLFRGINLADGKWHRVAISVQKKNVTLILDCKKKITKFLDRSDHPIIDVNGIIVFGTRILDEEVFEGDIQQLLIVADPRAAHDYCEHYSPDCDTAVPDAPQSQDPNQDEYYTDGEGEGDTYYYEYPYYEDVDEAVKPEAPTTKPAPPGVAAGERPETKQDYPSPTPSPEAGNPSRQTKGAAPVDDPLVDEYNYETINEEYFTPLPYEDINYNEEVDPQGGLTENAVEAELPTSTVITYNETDAAQGGDDLDKDFTEETIKEYDGNYYYYDRTVSPDIGPGMPANQDTIYEGIGGPRGEKGQKGEPAIIEPGMLVEGPPGPEGPAGLPGPPGPTGPVGLMGDPGERGPPGRPGLPGADGLPGPPGTMLMLPFRFSGGGDAGSKGPMVSAQEAQAQAILQQARLALRGPAGPMGLTGRPGPMGPPGSGGLKGEAGEMGPQGPRGIQGPPGPAGKPGRRGRAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGNRGEPGPHGPPGAPGEDGERGDDGEVGPRGLPGEPGPRGLLGPKGPPGPPGPPGVAGMDGQTGPKGNVGPQGEPGPPGQQGNPGAQGLPGPQGPIGPPGEKGPLGKPGLPGMPGADGPPGHPGKEGPPGEKGSQGPPGPQGPIGYPGPRGVKGADGVRGLKGTKGEKGEDGFPGFKGDMGIKGDRGEIGPPGPRGEDGPEGPKGRSGPNGDPGPLGPAGEKGKLGVPGLPGYPGRQGPKGSIGFPGFPGANGEKGTRGTPGKPGPRGQRGPTGPRGERGPRGSTGKPGPKGNSGGDGPPGPPGERGPPGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQGLPGLTGKEGTKGDPGPAGLPGKDGPPGLRGFPGERGLPGPIGSPGLKGNEGPPGPPGPAGSPGERGPAGSAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGIQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPAGADGEPGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPSGPPGADGPQGPAGGIGNPGAVGEKGEAGPSGAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDGLRGIPGPVGEQGLPGSPGPDGPPGPLGPPGLPGLKGDSGPKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSAGPKGEQGITGPSGPIGPPGPPGLPGPPGPKGAKGSSGPTGPKGESGLPGPPGPPGPPGEVIQPLPIQSSKRTRRNIDASQLVDDGNADNYMDYADGMEEIFGSLNSLKLEIEQMKHPLGTQHNPARTCKDLQLCHPDFPDGEYWVDPNQGCSRDSFKVYCNFTAGGETCIFPDKKSEGARITSWPKENPGSWFSEFKRGKLLSYVDSDGNPIGVVQMTFLRLLSASAHQNITYNCYQSVAWHDATTDSYDKAIRFLGSNDEEMSYDNNPYIRAAFDGCAAKKGYQKTVLEINTPKVEQVPIVDIMFNDFGEASQKFGFEVGPACFMG", "length": 1808, "header": "tr|A0A8V1ADR4-1|A0A8V1ADR4_CHICK Computationally mapped isoform of Collagen type V alpha 1 chain OS=Gallus gallus OX=9031 GN=COL5A1 PE=1 SV=1 CANONICAL=A0A8V1A8M8-1" }, "locus": { "chromosome": "17", "start_pos": 8167503, "end_pos": 8042107, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068870.1", "url": "https://www.ensembl.org/id/ENSGALT00010068870.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042312.1", "url": "https://www.ensembl.org/id/ENSGALP00010042312.1" } ] } }, { "isoform_ac": "A0A8V1AGB2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8M8/entry#A0A8V1AGB2-1", "sequence": { "sequence": "MDTHTRWKRRSWIRNWQLHVALVLLGAAALGRAAEPADLLKVLDFHNLPDGITRTTGFCTSRRSSKEADVAYRVTKDAQLSAPTKQLYPASPFPEDFSILTTVKAKKGGQSFLISIYNEQGIQQIGVEMGRSPVFLYEDHTGKPGPEDYPLFRGINLADGKWHRVAISVQKKNVTLILDCKKKITKFLDRSDHPIIDVNGIIVFGTRILDEEVFEGDIQQLLIVADPRAAHDYCEHYSPDCDTAVPDAPQSQDPNQDEYYTDGEGEGDTYYYEYPYYEDVDEAVKPEAPTTKPAPPGVAAGERPETKQDYPSPTPSPEAGNPSRQTKGAAPVDDPLVDEYNYETINEEYFTPLPYEDINYNEEVDPQGGLTENAVEAELPTSTVITYNETDAAQGGDDLDKDFTEETIKEYDGNYYYYDRTVSPDIGPGMPANQDTIYEGIGGPRGEKGQKGEPAIIEPGMLVEGPPGPEGPAGLPGPPGPTGPVGLMGDPGERGPPGRPGLPGADGLPGPPGTMLMLPFRFSGGGDAGSKGPMVSAQEAQAQAILQQARLALRGPAGPMGLTGRPGPMGPPGSGGLKGEAGEMGPQGPRGIQGPPGPAGKPGRRGRAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGNRGEPGPHGPPGAPGEDGERGDDGEVGPRGLPGEPGPRGLLGPKGPPGPPGPPGVAGMDGQTGPKGNVGPQGEPGPPGQQGNPGAQGLPGPQGPIGPPGEKGPLGKPGLPGMPGADGPPGHPGKEGPPGEKGSQGPPGPQGPIGYPGPRGVKGADGVRGLKGTKGEKGEDGFPGFKGDMGIKGDRGEIGPPGPRGEDGPEGPKGRSGPNGDPGPLGPAGEKGKLGVPGLPGYPGRQGPKGSIGFPGFPGANGEKGTRGTPGKPGPRGQRGPTGPRGERGPRGSTGKPGPKGNSGGDGPPGPPGERGPPGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQGLPGLTGKEGTKGDPGPAGLPGKDGPPGLRGFPGERGLPGPIGSPGLKGNEGPPGPPGPAGSPGERGPAGSAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGIQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPAGADGEPGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPSGPPGADGPQGPAGGIGNPGAVGEKGEPGESGEPGLPGEVGLPGPKGERGEKGEAGPSGAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDGLRGIPGPVGEQGLPGSPGPDGPPGPLGPPGLPGLKGDSGPKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSAGPKGEQGITGPSGPIGPPGPPGLPGPPGPKGAKGSSGPTGPKGESGLPGPPGPPGPPGEVIQPLPIQSSKRTRRNIDASQLVDDGNADNYMDYADGMEEIFGSLNSLKLEIEQMKHPLGTQHNPARTCKDLQLCHPDFPDGEYWVDPNQGCSRDSFKVYCNFTAGGETCIFPDKKSEGARITSWPKENPGSWFSEFKRGKLLSYVDSDGNPIGVVQMTFLRTSLTTATSP", "length": 1738, "header": "tr|A0A8V1AGB2-1|A0A8V1A8M8_CHICK Computationally mapped isoform of Collagen type V alpha 1 chain OS=Gallus gallus OX=9031 GN=COL5A1 PE=1 SV=1 CANONICAL=A0A8V1A8M8-1" }, "locus": { "chromosome": "17", "start_pos": 8165206, "end_pos": 8042107, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068867.1", "url": "https://www.ensembl.org/id/ENSGALT00010068867.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042309.1", "url": "https://www.ensembl.org/id/ENSGALP00010042309.1" } ] } }, { "isoform_ac": "A0A8V1AIK7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8M8/entry#A0A8V1AIK7-1", "sequence": { "sequence": "MDTHTRWKRRSWIRNWQLHVALVLLGAAALGRAAEPADLLKVLDFHNLPDGITRTTGFCTSRRSSKEADVAYRVTKDAQLSAPTKQLYPASPFPEDFSILTTVKAKKGGQSFLISIYNEQGIQQIGVEMGRSPVFLYEDHTGKPGPEDYPLFRGINLADGKWHRVAISVQKKNVTLILDCKKKITKFLDRSDHPIIDVNGIIVFGTRILDEEVFEGDIQQLLIVADPRAAHDYCEHYSPDCDTAVPDAPQSQDPNQDEYYTDGEGEGDTYYYEYPYYEDVDEAVKPEAPTTKPAPPGVAAGERPETKQDYPSPTPSPEAGNPSRQTKGAAPVDDPLVDEYNYETINEEYFTPLPYEDINYNEEVDPQGGLTENAVEAELPTSTVITYNETDAAQGGDDLDKDFTEETIKEYDGNYYYYDRTVSPDIGPGMPANQDTIYEGIGGPRGEKGQKGEPAIIEPGMLVEGPPGPEGPAGLPGPPGPTGPVGLMGDPGERGPPGRPGLPGADGLPGPPGTMLMLPFRFSGGGDAGSKGPMVSAQEAQAQAILQQARLALRGPAGPMGLTGRPGPMGPPGSGGLKGEAGEMGPQGPRGIQGPPGPAGKPGRRGRAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGNRGEPGPHGPPGAPGEDGERGDDGEVGPRGLPGEPGPRGLLGPKGPPGPPGPPGVAGMDGQTGPKGNVGPQGEPGPPGQQGNPGAQGLPGPQGPIGPPGEKGPLGKPGLPGMPGADGPPGHPGKEGPPGEKGSQGPPGPQGPIGYPGPRGVKGADGVRGLKGTKGEKGEDGFPGFKGDMGIKGDRGEIGPPGPRGEDGPEGPKGRSGPNGDPGPLGPAGEKGKLGVPGLPGYPGRQGPKGSIGFPGFPGANGEKGTRGTPGKPGPRGQRGPTGPRGERGPRGSTGKPGPKGNSGGDGPPGPPGERGPPGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQGLPGLTGKEGTKGDPGPAGLPGKDGPPGLRGFPGERGLPGPIGSPGLKGNEGPPGPPGPAGSPGERGPAGSAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGIQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPAGADGEPGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPSGPPGADGPQGPAGGIGNPGAVGEKGEPGESGEPGLPGEVGLPGPKGERGEKGEAGPSGAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDGLRGIPGPVGEQGLPGSPGPDGPPGPLGPPGLPGLKGDSGPKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSAGPKGEQGITGPSGPIGPPGPPGLPGPPGPKGAKGSSGPTGPKGESGLPGPPGPPGPPGEVIQPLPIQSSKRTRRNIDASQLVDDGNADNYMDYADGMEEIFGSLNSLKLEIEQMKHPLGTQHNPARTCKDLQLCHPDFPDGEYWVDPNQGCSRDSFKVYCNFTAGGETCIFPDKKSEGARITSWPKENPGSWFSEFKRGKLVRCISVLSVFFNPCRILQSKMARWPKEQPSTWYSQYKRGSLIDGQCHVSPSVH", "length": 1762, "header": "tr|A0A8V1AIK7-1|A0A8V1A8M8_CHICK Computationally mapped isoform of Collagen type V alpha 1 chain OS=Gallus gallus OX=9031 GN=COL5A1 PE=1 SV=1 CANONICAL=A0A8V1A8M8-1" }, "locus": { "chromosome": "17", "start_pos": 8163888, "end_pos": 8042107, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068866.1", "url": "https://www.ensembl.org/id/ENSGALT00010068866.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042308.1", "url": "https://www.ensembl.org/id/ENSGALP00010042308.1" } ] } }, { "isoform_ac": "A0A8V1AKE8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8M8/entry#A0A8V1AKE8-1", "sequence": { "sequence": 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"start_aa": "Thr", "end_pos": 482, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr482", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-GGA-1650814", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1650814", "resource": "Reactome", "description": "Collagen biosynthesis and modifying enzymes" }, { "id": "R-GGA-2022090", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2022090", "resource": "Reactome", "description": "Assembly of collagen fibrils and other multimeric structures" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": 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"table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A8P2-1", "uniprot_ac": "A0A8V1A8P2", "uniprot_id": "A0A8V1A8P2_CHICK", "mass": { "chemical_mass": 12072.0, "monoisotopic_mass": 12072.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "A0A8V1A8P2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8P2/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A8P2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8P2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8P2", "locus": {} } ], "crossref": [ { "id": "A0A8V1A8P2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A8P2", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR029290", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029290", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR15562", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15562", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15562:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15562:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15331", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15331", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1A8P2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8P2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A8P2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8P2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQNTFWSGLRECHHLPELEEAAGSPEEAADSPETSSTSSTMDAPMDPETRTSPAAAEAKQDLLGTLPQRFHMPAPKVLCRPSAQRWVKPCCTRSCGESLERTLTIRYPR", "length": 109, "header": "tr|A0A8V1A8P2-1|A0A8V1A8P2_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1A8P2-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A8P2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8P2/entry#A0A8V1A8P2-1", "sequence": { "sequence": "MQNTFWSGLRECHHLPELEEAAGSPEEAADSPETSSTSSTMDAPMDPETRTSPAAAEAKQDLLGTLPQRFHMPAPKVLCRPSAQRWVKPCCTRSCGESLERTLTIRYPR", "length": 109, "header": "tr|A0A8V1A8P2-1|A0A8V1A8P2_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1A8P2-1" }, "locus": { "chromosome": "20", "start_pos": 5454840, "end_pos": 5454514, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010060994.1", "url": "https://www.ensembl.org/id/ENSGALT00010060994.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010037736.1", "url": "https://www.ensembl.org/id/ENSGALP00010037736.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A8Q4-1", "uniprot_ac": "A0A8V1A8Q4", "uniprot_id": "A0A8V1A8Q4_CHICK", "mass": { "chemical_mass": 52680.0, "monoisotopic_mass": 52680.0 }, "refseq": { "ac": "XP_015155009", "name": "plexin domain-containing protein 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015155009" }, "gene_names": [ { "name": "PLXDC1", "type": "recommended", "evidence": [ { "id": "A0A8V1A8Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8Q4" } ] }, { "name": "PLXDC1", "type": "synonym", "evidence": [ { "id": "XP_015155009", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015155009" } ] } ], "protein_names": [ { "name": "Plexin domain containing 1", "type": "synonym", "evidence": [ { "id": "A0A8V1A8Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8Q4/entry#names_and_taxonomy" } ] }, { "name": "plexin domain-containing protein 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015155009", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015155009" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052558.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015155009.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015155009", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015155009" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A8Q4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8Q4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PLXDC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8Q4", "locus": { "chromosome": "27", "start_pos": 4077345, "end_pos": 4091284, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010026681", "url": "https://www.ensembl.org/id/ENSGALG00010026681" } ] } } ], "crossref": [ { "id": "A0A8V1A8Q4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A8Q4", "database": "AlphaFoldDB", "categories": [] }, { "id": "771862", "url": "https://www.ncbi.nlm.nih.gov/gene/771862", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002165", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002165", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031152", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031152", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:771862", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:771862", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PHKHREA", "url": "https://omabrowser.org/oma/group/PHKHREA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A8Q4", "url": "https://www.orthodb.org/?gene=A0A8V1A8Q4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ADM7", "url": "https://www.orthodb.org/?gene=A0A8V1ADM7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13055", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13055", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13055:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13055:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01437", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01437", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015155009", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015155009", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1A8Q4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8Q4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A8Q4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8Q4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ADM7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADM7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ADM7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADM7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRGGALILLGLIALCGRRGARGAGPPEGQRGAGQPQRMHISQDLVGRSLLIDTLLDNETRIVEDNHSYYVSRTYGPGAARRQGLWVDMAAADSSHVKVHGILSNTHRQASRIVLSFDFPFYGHLLRQVTIATGGFIFMGDVIHRMLTATQYIAPLMANFNPSYSRNSTVQYLDNGTVFVVQWDKVYLQGKEDVGSFTFQAALHSSGRIVFGYKEIPVPVLQISAAQHPVKAGLSDAFMVLNASPEVPAPAAESRRRTIYEYHRVELDTSKITNMSAVEFTPLPTCLQHRSCEVCVSSTLTFNCSWCHVLQRCSSGFDRHREEWLSYGCAQQADTKSCEDLAEDDRYSAPPDGSSSPLDEDIATPTASLFIDSLTTEDDTKLNQQAGSEGVGNDLPSAAVGAPIHTGTIVGIVLAVLLIAAIILAGIYINSHPTSNAALFFIERRPHRWPAMKFRNHTNHATYSEVEAASHEKEGFVEAEQC", "length": 481, "header": "tr|A0A8V1A8Q4-1|A0A8V1A8Q4_CHICK Isoform 1 of Plexin domain containing 1 OS=Gallus gallus OX=9031 GN=PLXDC1 PE=3 SV=1 CANONICAL=A0A8V1A8Q4-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A8Q4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8Q4/entry#A0A8V1A8Q4-1", "sequence": { "sequence": "MRGGALILLGLIALCGRRGARGAGPPEGQRGAGQPQRMHISQDLVGRSLLIDTLLDNETRIVEDNHSYYVSRTYGPGAARRQGLWVDMAAADSSHVKVHGILSNTHRQASRIVLSFDFPFYGHLLRQVTIATGGFIFMGDVIHRMLTATQYIAPLMANFNPSYSRNSTVQYLDNGTVFVVQWDKVYLQGKEDVGSFTFQAALHSSGRIVFGYKEIPVPVLQISAAQHPVKAGLSDAFMVLNASPEVPAPAAESRRRTIYEYHRVELDTSKITNMSAVEFTPLPTCLQHRSCEVCVSSTLTFNCSWCHVLQRCSSGFDRHREEWLSYGCAQQADTKSCEDLAEDDRYSAPPDGSSSPLDEDIATPTASLFIDSLTTEDDTKLNQQAGSEGVGNDLPSAAVGAPIHTGTIVGIVLAVLLIAAIILAGIYINSHPTSNAALFFIERRPHRWPAMKFRNHTNHATYSEVEAASHEKEGFVEAEQC", "length": 481, "header": "tr|A0A8V1A8Q4-1|A0A8V1A8Q4_CHICK Isoform 1 of Plexin domain containing 1 OS=Gallus gallus OX=9031 GN=PLXDC1 PE=3 SV=1 CANONICAL=A0A8V1A8Q4-1" }, "locus": { "chromosome": "27", "start_pos": 4088472, "end_pos": 4078189, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010064754.1", "url": "https://www.ensembl.org/id/ENSGALT00010064754.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039606.1", "url": "https://www.ensembl.org/id/ENSGALP00010039606.1" } ] } }, { "isoform_ac": "A0A8V1ADM7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8Q4/entry#A0A8V1ADM7-1", "sequence": { "sequence": "MVFEAGVPRITLAARKIPAPGPPEGQRGAGQPQRMHISQDLVGRSLLIDTLLDNETRIVEDNHSYYVSRTYGPGAARRQGLWVDMAAADSSHVKVHGILSNTHRQASRIVLSFDFPFYGHLLRQVTIATGGFIFMGDVIHRMLTATQYIAPLMANFNPSYSRNSTVQYLDNGTVFVVQWDKVYLQGKEDVGSFTFQAALHSSGRIVFGYKEIPVPVLQISAAQHPVKAGLSDAFMVLNASPEVPESRRRTIYEYHRVELDTSKITNMSAVEFTPLPTCLQHRSCEVCVSSTLTFNCSWCHVLQRCSSGFDRHREEWLSYGCAQQADTKSCEDLAEDDRYSAPPDGSSSPLDEDIATPTASLFIDSLTTEDDTKLNQQAGSEGVGNDLPSAAVGAPIHTGTIVGIVLAVLLIAAIILAGIYINSHPTSNAALFFIERRPHRWPAMKFRNHTNHATYSEVEAASHEKEGFVEAEQC", "length": 474, "header": "tr|A0A8V1ADM7-1|A0A8V1ADM7_CHICK Computationally mapped isoform of Plexin domain containing 1 OS=Gallus gallus OX=9031 GN=PLXDC1 PE=3 SV=1 CANONICAL=A0A8V1A8Q4-1" }, "locus": { "chromosome": "27", "start_pos": 4090975, "end_pos": 4078189, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010064759.1", "url": "https://www.ensembl.org/id/ENSGALT00010064759.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039608.1", "url": "https://www.ensembl.org/id/ENSGALP00010039608.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:771862", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:771862", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZEE4-1", "protein_name": "Plexin domain containing 1", "gene_name": "Plxdc1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSRRGPGSCGVRRGAPGGGDPGVAPRPLGPPARAPQGRNAAHRSRCPLRSGSPFSQPRVASSTAAAAAPTRRSSAPTMRAQLWLLQLLLLCGTARALSPATPAGHDERQGSAWTAKRTRQGWNRRVRESPGQVLKPGKTQLSQDLGGDSLAIDTLPDNRTRVVEDNHNYYVSRVYGPGEQRTRDLWVDLSVANRNHVKVHRILSSSHRQASRVVLSFDFPFYGHPLRQITIATGGFIFMGDVLHRMLTATQYVAPLMANFNPGYSDNSTVAYFDNGTVFVVQWDHVYLQGREDRGSFTFQAALHQDGRIVFGYKEIPMAVLDISSAQHPVKAGLSDAFMILNSSPEVPESRRRTIFEYHRVELDSSKITTTSAVEFTPLPTCLQHQSCDACMSSNLTFNCSWCYVLQRCSSGFDRYRQEWLTYGCAQEAEGKTCEHFQDEGHYSASPDSSFSPSDGGSTTSSSLFIDSLTTEDDTKLNPYAEGDGLPDNSSPKTKGPPVHLGTIVGIVLAVLLVAAIILAGIYISGHPNSNAALFFIERRPHHWPAMKFHNHPNHSTYTEVEPSGHEKEGFVEAEQC", "length": 577 }, "evidence": [ { "id": "A0A8V1A8Q4", "url": "https://omabrowser.org/oma/group/A0A8V1A8Q4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1RWK7-1", "protein_name": "Plexin domain containing 1", "gene_name": "PLXDC1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRAELWLLVLVFREAARALSPPPGAGQDAGRGPGWATKGITQGWNRRAGGSPGQVSEPDRTQLSQDLGGGTLAIDTRPENGTRVVEDNHSYYVSHLYGPSEPRSQDLWVDVAKANQSQVKVHRILSNTHRQASRVVLSFDFPFYGHPLRQITIATGGFIFMGDVIHRMLTATQYVAPLMANFNPGYSDNSTVAYFDNGTVFVVQWDHVYLQGREDRGSFTFQAALHQDGRIVFGYREIPMSVLEISSSQHPVKAGLSDAFMILNPSPDVPESRRRTIFEYHRVELDPSKITSMSAVEFTPLPTCLQHQSCDACMSSDLTFNCSWCHVLQRCSSGFDRYRQEWLAYGCAQEAEGRTCEDFQDEDASSSPDSSFSPFDRDLTTTSSTLFVDSLTTEDDTKLNPYAGGEGLQNNLSPETKGPPVHLGTIVGIVLAVLLVAAIILAGIYINGHPTSNAALFFIERRPHHWPAMKFRNHPNHSTYTEVEPSGHEKEGFVEAEQC", "length": 499 }, "evidence": [ { "id": "A0A8V1A8Q4", "url": "https://omabrowser.org/oma/group/A0A8V1A8Q4/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q8IUK5-1", "protein_name": "Plexin domain-containing protein 1", "gene_name": "PLXDC1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRGELWLLVLVLREAARALSPQPGAGHDEGPGSGWAAKGTVRGWNRRARESPGHVSEPDRTQLSQDLGGGTLAMDTLPDNRTRVVEDNHSYYVSRLYGPSEPHSRELWVDVAEANRSQVKIHTILSNTHRQASRVVLSFDFPFYGHPLRQITIATGGFIFMGDVIHRMLTATQYVAPLMANFNPGYSDNSTVVYFDNGTVFVVQWDHVYLQGWEDKGSFTFQAALHHDGRIVFAYKEIPMSVPEISSSQHPVKTGLSDAFMILNPSPDVPESRRRSIFEYHRIELDPSKVTSMSAVEFTPLPTCLQHRSCDACMSSDLTFNCSWCHVLQRCSSGFDRYRQEWMDYGCAQEAEGRMCEDFQDEDHDSASPDTSFSPYDGDLTTTSSSLFIDSLTTEDDTKLNPYAGGDGLQNNLSPKTKGTPVHLGTIVGIVLAVLLVAAIILAGIYINGHPTSNAALFFIERRPHHWPAMKFRSHPDHSTYAEVEPSGHEKEGFMEAEQC", "length": 500 }, "evidence": [ { "id": "A0A8V1A8Q4", "url": "https://omabrowser.org/oma/group/A0A8V1A8Q4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q91ZV7-1", "protein_name": "Plexin domain-containing protein 1", "gene_name": "Plxdc1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRAQLWLLQLLLLRGAARALSPATPAGHNEGQDSAWTAKRTRQGWSRRPRESPAQVLKPGKTQLSQDLGGGSLAIDTLPDNRTRVVEDNHNYYVSRVYGPGEKQSQDLWVDLAVANRSHVKIHRILSSSHRQASRVVLSFDFPFYGHPLRQITIATGGFIFMGDMLHRMLTATQYVAPLMANFNPGYSDNSTVAYFDNGTVFVVQWDHVYLQDREDRGSFTFQAALHRDGRIVFGYKEIPMAVLDISSAQHPVKAGLSDAFMILNSSPEVPASQRRTIFEYHRVELDSSKITTTSAVEFTPLPTCLQHQSCDTCVSSNLTFNCSWCHVLQRCSSGFDRYRQEWLTYGCAQEAEGKTCEDFQDDSHYSASPDSSFSPFNGDSTTSSSLFIDSLTTEDDTKLNPYAEGDGLPDHSSPKSKGPPVHLGTIVGIVLAVLLVAAIILAGIYISGHPNSNAALFFIERRPHHWPAMKFHNHPNHSTYTEVEPSGHEKEGFVEAEQC", "length": 500 }, "evidence": [ { "id": "A0A8V1A8Q4", "url": "https://omabrowser.org/oma/group/A0A8V1A8Q4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A8Q4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8Q4" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A8Q4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8Q4" } ], "pmid": "" }, { "name": "receptor complex", "id": "GO:0043235", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043235", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A8Q4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8Q4" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A8Q4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8Q4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 166, "end_pos": 168, "annotation": "n_glycosylation_sequon" }, { "start_pos": 174, "end_pos": 176, "annotation": "n_glycosylation_sequon" }, { "start_pos": 241, "end_pos": 243, "annotation": 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"end_pos": 168 }, { "start_pos": 174, "end_pos": 176 }, { "start_pos": 241, "end_pos": 243 }, { "start_pos": 273, "end_pos": 275 }, { "start_pos": 302, "end_pos": 304 }, { "start_pos": 455, "end_pos": 457 }, { "start_pos": 57, "end_pos": 59 }, { "start_pos": 65, "end_pos": 67 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": 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"field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A8Q7-1", "uniprot_ac": "A0A8V1A8Q7", "uniprot_id": "A0A8V1A8Q7_CHICK", "mass": { "chemical_mass": 32267.0, "monoisotopic_mass": 32267.0 }, "refseq": {}, "gene_names": [ { "name": "RIT1", "type": "recommended", "evidence": [ { "id": "A0A8V1A8Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8Q7" } ] } ], "protein_names": [ { "name": "small monomeric GTPase", "type": "recommended", "evidence": [ { "id": "A0A8V1A8Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8Q7/entry#names_and_taxonomy" } ] }, { "name": "3.6.5.2", "type": "synonym", "evidence": [ { "id": "A0A8V1A8Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8Q7/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A8Q7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8Q7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RIT1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8Q7", "locus": { "chromosome": "25", "start_pos": 2215182, "end_pos": 2220819, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028448", "url": "https://www.ensembl.org/id/ENSGALG00010028448" } ] } } ], "crossref": [ { "id": "A0A8V1A8Q7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A8Q7", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd04141", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04141", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001806", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001806", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005225", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005225", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A8Q7", "url": "https://www.orthodb.org/?gene=A0A8V1A8Q7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AGD8", "url": "https://www.orthodb.org/?gene=A0A8V1AGD8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24070", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24070", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00071", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00071", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "19669", "url": "https://www.rhea-db.org/rhea/19669", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1A8Q7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8Q7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A8Q7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8Q7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGD8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGD8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGD8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGD8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MWSGGGASRGAVSRWRGPAAILGSPPELRAGPCGGGGGVRCVAERPEVSGERSGGAARRAAGLTPFSSPLRGGASLGAEEMDAGARPGGAGQPREYKLVMLGAGGVGKSAMTMQFISHRFPEDHDPTIEDAYKIRIRIDDEPANLDILDTAGQAEFTAMRDQYMRAGEGFIICYSITDRRSFHEVREFKQLIYRVRRTDDTPVVLVGNKSDLTQLRQVSKEEGSALAREFNCPFFETSAAYRYYIDDVFHALVREIRRKEKEAVMAMEKKSKPKSSVWKRLKSPFRRKKDSVT", "length": 293, "header": "tr|A0A8V1A8Q7-1|A0A8V1A8Q7_CHICK Isoform 1 of small monomeric GTPase OS=Gallus gallus OX=9031 GN=RIT1 PE=3 SV=1 CANONICAL=A0A8V1A8Q7-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A8Q7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8Q7/entry#A0A8V1A8Q7-1", "sequence": { "sequence": "MWSGGGASRGAVSRWRGPAAILGSPPELRAGPCGGGGGVRCVAERPEVSGERSGGAARRAAGLTPFSSPLRGGASLGAEEMDAGARPGGAGQPREYKLVMLGAGGVGKSAMTMQFISHRFPEDHDPTIEDAYKIRIRIDDEPANLDILDTAGQAEFTAMRDQYMRAGEGFIICYSITDRRSFHEVREFKQLIYRVRRTDDTPVVLVGNKSDLTQLRQVSKEEGSALAREFNCPFFETSAAYRYYIDDVFHALVREIRRKEKEAVMAMEKKSKPKSSVWKRLKSPFRRKKDSVT", "length": 293, "header": "tr|A0A8V1A8Q7-1|A0A8V1A8Q7_CHICK Isoform 1 of small monomeric GTPase OS=Gallus gallus OX=9031 GN=RIT1 PE=3 SV=1 CANONICAL=A0A8V1A8Q7-1" }, "locus": { "chromosome": "25", "start_pos": 2220620, "end_pos": 2217485, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068900.1", "url": "https://www.ensembl.org/id/ENSGALT00010068900.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042342.1", "url": "https://www.ensembl.org/id/ENSGALP00010042342.1" } ] } }, { "isoform_ac": "A0A8V1AGD8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8Q7/entry#A0A8V1AGD8-1", "sequence": { "sequence": "MDAGARPGGAGQPREYKLVMLGAGGVGKSAMTMQFISHRFPEDHDPTIEDAYKIRIRIDDEPANLDILDTAGQAEFTAMRDQYMRAGEGFIICYSITDRRSFHEVREFKQLIYRVRRTDDTPVVLVGNKSDLTQLRQVCGSQRGPPFCFSFRMQP", "length": 155, "header": "tr|A0A8V1AGD8-1|A0A8V1A8Q7_CHICK Computationally mapped isoform of small monomeric GTPase OS=Gallus gallus OX=9031 GN=RIT1 PE=3 SV=1 CANONICAL=A0A8V1A8Q7-1" }, "locus": { "chromosome": "25", "start_pos": 2220380, "end_pos": 2218574, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068899.1", "url": "https://www.ensembl.org/id/ENSGALT00010068899.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042341.1", "url": "https://www.ensembl.org/id/ENSGALP00010042341.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A8Q7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8Q7" } ], "pmid": "" }, { "name": "calmodulin binding", "id": "GO:0005516", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005516", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A8Q7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8Q7" } 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"publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A8U2-1", "uniprot_ac": "A0A8V1A8U2", "uniprot_id": "A0A8V1A8U2_CHICK", "mass": { "chemical_mass": 20566.0, "monoisotopic_mass": 20566.0 }, "refseq": {}, "gene_names": [ { "name": "LOC121112063", "type": "recommended", "evidence": [ { "id": "A0A8V1A8U2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8U2" } ] } ], "protein_names": [ { "name": "Protein JTB", "type": "recommended", "evidence": [ { "id": "A0A8V1A8U2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8U2/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Required for normal cytokinesis during mitosis. Plays a role in the regulation of cell proliferation. May be a component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Increases AURKB activity. Inhibits apoptosis induced by TGFB1. Overexpression induces swelling of mitochondria and reduces mitochondrial membrane potential.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A8U2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8U2#function" }, { "database": "UniProtKB", "id": "ARBA00058368", "url": "https://www.uniprot.org/uniprotkb/ARBA00058368#function" }, { "database": "UniProtKB", "id": "A0A8V1AG95", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG95#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A8U2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8U2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC121112063", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8U2", "locus": {} } ], "crossref": [ { "id": "A0A8V1A8U2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A8U2", "database": "AlphaFoldDB", "categories": [] }, { "id": "121112063", "url": "https://www.ncbi.nlm.nih.gov/gene/121112063", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR008657", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008657", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "TITRSCD", "url": "https://omabrowser.org/oma/group/TITRSCD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR13041", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13041", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13041:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13041:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05439", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05439", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1A8U2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8U2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A8U2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8U2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AG95", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG95", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AG95-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG95-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MWSRRGAGPRCCALCALLGALCALLGAGLRPVTAVAAMAASEERRSASPATPCWRREEFVVARECGRCSGFEVKSIPECGPTGFVEKISCAASKRDEYKRSSRRRAQPAGLPGGRSAARHRSARPPAHLPGQHRGGTAGAAHPAAVPPARVPPGDGFPARLGVGTRGAGAARPPGRSGGGRRGGRGRSGQSAADGRGPPGPP", "length": 202, "header": "tr|A0A8V1A8U2-1|A0A8V1A8U2_CHICK Isoform 1 of Protein JTB OS=Gallus gallus OX=9031 GN=LOC121112063 PE=3 SV=1 CANONICAL=A0A8V1A8U2-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A8U2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8U2/entry#A0A8V1A8U2-1", "sequence": { "sequence": "MWSRRGAGPRCCALCALLGALCALLGAGLRPVTAVAAMAASEERRSASPATPCWRREEFVVARECGRCSGFEVKSIPECGPTGFVEKISCAASKRDEYKRSSRRRAQPAGLPGGRSAARHRSARPPAHLPGQHRGGTAGAAHPAAVPPARVPPGDGFPARLGVGTRGAGAARPPGRSGGGRRGGRGRSGQSAADGRGPPGPP", "length": 202, "header": "tr|A0A8V1A8U2-1|A0A8V1A8U2_CHICK Isoform 1 of Protein JTB OS=Gallus gallus OX=9031 GN=LOC121112063 PE=3 SV=1 CANONICAL=A0A8V1A8U2-1" }, "locus": { "chromosome": "25", "start_pos": 1852002, "end_pos": 1848652, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066327.1", "url": "https://www.ensembl.org/id/ENSGALT00010066327.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040593.1", "url": "https://www.ensembl.org/id/ENSGALP00010040593.1" } ] } }, { "isoform_ac": "A0A8V1AG95-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8U2/entry#A0A8V1AG95-1", "sequence": { "sequence": "MWSRRGAGPRCCALCALLGALCALLGAGLRPVTAVAAMAASEERRSASPATPCWRREEFVVARECGRCSGFEVKSIPECGPTGFVEKISCAASKRDEYKSCRSAVLEARIFWRFVGSMICVAAACAVLVVWRQRALDRRALEKVRKQIESI", "length": 151, "header": "tr|A0A8V1AG95-1|A0A8V1A8U2_CHICK Computationally mapped isoform of Protein JTB OS=Gallus gallus OX=9031 GN=LOC121112063 PE=3 SV=1 CANONICAL=A0A8V1A8U2-1" }, "locus": { "chromosome": "25", "start_pos": 1852002, "end_pos": 1851062, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066326.1", "url": "https://www.ensembl.org/id/ENSGALT00010066326.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040592.1", "url": "https://www.ensembl.org/id/ENSGALP00010040592.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", 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"cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A8U2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8U2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 51 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 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"sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A8V5-1", "uniprot_ac": "A0A8V1A8V5", "uniprot_id": "A0A8V1A8V5_CHICK", "mass": { "chemical_mass": 18208.0, "monoisotopic_mass": 18208.0 }, "refseq": {}, "gene_names": [ { "name": "NRARP", "type": "recommended", "evidence": [ { "id": "A0A8V1A8V5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8V5" } ] } ], "protein_names": [ { "name": "NOTCH regulated ankyrin repeat protein", "type": "synonym", "evidence": [ { "id": "A0A8V1A8V5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8V5/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A8V5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8V5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NRARP", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8V5", "locus": { "chromosome": "17", "start_pos": 1327465, "end_pos": 1329041, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028477", "url": "https://www.ensembl.org/id/ENSGALG00010028477" } ] } } ], "crossref": [ { "id": "A0A8V1A8V5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A8V5", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR002110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051226", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051226", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A8V5", "url": "https://www.orthodb.org/?gene=A0A8V1A8V5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24179", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24179", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24179:SF21", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24179:SF21", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12796", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12796", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1A8V5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8V5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A8V5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8V5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSQSDVSPCAAPPSQRVFQEAVRRGNTKELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLANRDGWSALHIAAFGGHQDIVLYLITKAKYSAGARRTAAHPLPSSLFDSVWFSFRGLFSYCNFFFSIYLGCTHSIHGFSLTSAQML", "length": 165, "header": "tr|A0A8V1A8V5-1|A0A8V1A8V5_CHICK Isoform 1 of NOTCH regulated ankyrin repeat protein OS=Gallus gallus OX=9031 GN=NRARP PE=3 SV=1 CANONICAL=A0A8V1A8V5-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A8V5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8V5/entry#A0A8V1A8V5-1", "sequence": { "sequence": "MSQSDVSPCAAPPSQRVFQEAVRRGNTKELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLANRDGWSALHIAAFGGHQDIVLYLITKAKYSAGARRTAAHPLPSSLFDSVWFSFRGLFSYCNFFFSIYLGCTHSIHGFSLTSAQML", "length": 165, "header": 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This record is derived from a genomic sequence (NC_052543.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015148358.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015148358", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015148358" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A940", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A940" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "IQCF6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A940", "locus": {} } ], "crossref": [ { "id": "A0A8V1A940", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A940", "database": "AlphaFoldDB", "categories": [] }, { "id": "101751993", "url": "https://www.ncbi.nlm.nih.gov/gene/101751993", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000048", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000048", "database": 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"MPSFFRSRPAPRGRPAAALPAGSRERTRRRWRGSAALCAEGGRMSRVPVGKVLLRNVIRHTGAHNKIQEETEMWKIREWEKQAEETYWRQRSRMLSDTSSSRMRSDGFDEEGHRADWKTKNSHFLDPVEDDLFRARSWNKKLYECEANMPDRWGHSGYKELYPEEFDTDSDQQERDKQNAVNGKKKSHLRKQSAHELHKRKKTKKSHKKKQKKRSHKKRKKKKKEQGRSSSDSSQENECSEEETSSIQKGKHKRKKKTRKVPAREPTSSSEQESDFSHASSSTTSSSEDSESEEKKEKRLTKKRKKRHNSVSERHSEVAEKRSKRKNWKVAADEKSEDSSEED", "length": 343, "header": "tr|A0A8V1A942-1|A0A8V1A942_CHICK Isoform 1 of NKAP domain containing 1 OS=Gallus gallus OX=9031 GN=C11orf57 PE=4 SV=1 CANONICAL=A0A8V1A942-1" }, "locus": { "chromosome": "24", "start_pos": 6210492, "end_pos": 6206577, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010061297.1", "url": "https://www.ensembl.org/id/ENSGALT00010061297.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010037901.1", "url": "https://www.ensembl.org/id/ENSGALP00010037901.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A944-1", "uniprot_ac": "A0A8V1A944", "uniprot_id": "A0A8V1A944_CHICK", "mass": { "chemical_mass": 37576.0, "monoisotopic_mass": 37576.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Translation elongation factor EFTs/EF1B dimerisation domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8V1A944", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A944/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Participates in mitochondrial translation.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A944", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A944#function" }, { "database": "UniProtKB", "id": "ARBA00094424", "url": "https://www.uniprot.org/uniprotkb/ARBA00094424#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A944", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A944" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A944", "locus": {} } ], "crossref": [ { "id": "A0A8V1A944", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A944", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR001816", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001816", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036402", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036402", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR11741", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11741", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11741:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11741:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A944", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A944", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A944-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A944-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTPNPLCVPITPNPLSVPMALCPHHPNLWQCPLCVPITPNPLSVPFVSPTPQTLSVSPLCPHGSVSPSPQSLAVSPLCPHHPKPPQCPLCVPMTPNPLCVPITPNPLNVPMALCPHHPKLSVSSLCPYDPKPAQCPHGAVSPHHPKAVSPLFPVALCPHPPNLRACPHICGVPTSVSPHLCPRDPQQSPPYPHITMSCPPPPPPGSMGENMALRRAAFLAVPPDCFIASYAHGPPPGEPPPPHTAPALGRYGALVACRVTEPGVSPDPAAVGRKVAQHVVGMAPLSVGGPGGDVGGGRGGRKEGGEEEEEEGEGEEEETRLLAQSFVLQPSLTVAEFVRSHGVAVLDFVRFQCGEEERG", "length": 359, "header": "tr|A0A8V1A944-1|A0A8V1A944_CHICK Isoform 1 of Translation elongation factor EFTs/EF1B dimerisation domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1A944-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A944-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A944/entry#A0A8V1A944-1", "sequence": { "sequence": "MTPNPLCVPITPNPLSVPMALCPHHPNLWQCPLCVPITPNPLSVPFVSPTPQTLSVSPLCPHGSVSPSPQSLAVSPLCPHHPKPPQCPLCVPMTPNPLCVPITPNPLNVPMALCPHHPKLSVSSLCPYDPKPAQCPHGAVSPHHPKAVSPLFPVALCPHPPNLRACPHICGVPTSVSPHLCPRDPQQSPPYPHITMSCPPPPPPGSMGENMALRRAAFLAVPPDCFIASYAHGPPPGEPPPPHTAPALGRYGALVACRVTEPGVSPDPAAVGRKVAQHVVGMAPLSVGGPGGDVGGGRGGRKEGGEEEEEEGEGEEEETRLLAQSFVLQPSLTVAEFVRSHGVAVLDFVRFQCGEEERG", "length": 359, "header": "tr|A0A8V1A944-1|A0A8V1A944_CHICK Isoform 1 of Translation elongation factor EFTs/EF1B dimerisation domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1A944-1" }, "locus": { "chromosome": "34", "start_pos": 2418401, "end_pos": 2417325, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010062840.1", "url": "https://www.ensembl.org/id/ENSGALT00010062840.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038825.1", "url": "https://www.ensembl.org/id/ENSGALP00010038825.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 50, "start_aa": "Thr", "end_pos": 50, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr50", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "translation elongation factor activity", "id": "GO:0003746", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003746", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A944", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A944" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 50 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A946-1", "uniprot_ac": "A0A8V1A946", "uniprot_id": "A0A8V1A946_CHICK", "mass": { "chemical_mass": 35152.0, "monoisotopic_mass": 35152.0 }, "refseq": { "ac": "XP_015155601", "name": "yjeF N-terminal domain-containing protein 3 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015155601" }, "gene_names": [ { "name": "YJEFN3", "type": "recommended", "evidence": [ { "id": "A0A8V1A946", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A946" } ] }, { "name": "YJEFN3", "type": "synonym", "evidence": [ { "id": "XP_015155601", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015155601" } ] } ], "protein_names": [ { "name": "ApoA-I-binding protein 2", "type": "recommended", "evidence": [ { "id": "A0A8V1A946", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A946/entry#names_and_taxonomy" } ] }, { "name": "yjeF N-terminal domain-containing protein 3 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015155601", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015155601" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052559.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015155601.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015155601", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015155601" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A946", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A946" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "YJEFN3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A946", "locus": { "chromosome": "28", "start_pos": 3893613, "end_pos": 3898926, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028511", "url": "https://www.ensembl.org/id/ENSGALG00010028511" } ] } } ], "crossref": [ { "id": "A0A8V1A946", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A946", "database": "AlphaFoldDB", "categories": [] }, { "id": "100857831", "url": "https://www.ncbi.nlm.nih.gov/gene/100857831", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004443", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004443", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032976", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032976", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036652", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036652", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:100857831", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100857831", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1A946", "url": "https://www.orthodb.org/?gene=A0A8V1A946", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AGQ9", "url": "https://www.orthodb.org/?gene=A0A8V1AGQ9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AKR9", "url": "https://www.orthodb.org/?gene=A0A8V1AKR9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13232", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13232", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13232:SF12", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13232:SF12", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015155601", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015155601", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1A946", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A946", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A946-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A946-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGQ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGQ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGQ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGQ9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AKR9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKR9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AKR9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKR9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNNRSIVQLYITAQSFSPGPLPGPCLARKATATPRRACPSPALPLLILPRSPSNRGRPLPRNGGDVPSAVPRRLGTEWGWRGSHGCPLPRSKAEAEAIEKELLEDYRFGRQQLIEMWGHACAVAVTKAFPLPSLPRKQPTVLVVCGPAQNGAIGLVCARHLRVFDYEPTIFYPKRSLDPLYRDFTTQCEKMDIPFLSYLPTEVQLINDAYNAVVDAVLGAEAELGEGRGPCAGILATLKHVRIPIVSLDVPSGWDVEAGSSGGISPDVLVSLMAPKQCARRFLGRQHFVAGRFVPYDVQKKFELNPPDYPGTECVVALRAPQ", "length": 322, "header": "tr|A0A8V1A946-1|A0A8V1A946_CHICK Isoform 1 of ApoA-I-binding protein 2 OS=Gallus gallus OX=9031 GN=YJEFN3 PE=4 SV=1 CANONICAL=A0A8V1A946-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A946-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A946/entry#A0A8V1A946-1", "sequence": { "sequence": "MNNRSIVQLYITAQSFSPGPLPGPCLARKATATPRRACPSPALPLLILPRSPSNRGRPLPRNGGDVPSAVPRRLGTEWGWRGSHGCPLPRSKAEAEAIEKELLEDYRFGRQQLIEMWGHACAVAVTKAFPLPSLPRKQPTVLVVCGPAQNGAIGLVCARHLRVFDYEPTIFYPKRSLDPLYRDFTTQCEKMDIPFLSYLPTEVQLINDAYNAVVDAVLGAEAELGEGRGPCAGILATLKHVRIPIVSLDVPSGWDVEAGSSGGISPDVLVSLMAPKQCARRFLGRQHFVAGRFVPYDVQKKFELNPPDYPGTECVVALRAPQ", "length": 322, "header": "tr|A0A8V1A946-1|A0A8V1A946_CHICK Isoform 1 of ApoA-I-binding protein 2 OS=Gallus gallus OX=9031 GN=YJEFN3 PE=4 SV=1 CANONICAL=A0A8V1A946-1" }, "locus": { "chromosome": "28", "start_pos": 3896833, "end_pos": 3893632, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069042.1", "url": "https://www.ensembl.org/id/ENSGALT00010069042.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042484.1", "url": "https://www.ensembl.org/id/ENSGALP00010042484.1" } ] } }, { "isoform_ac": "A0A8V1AGQ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A946/entry#A0A8V1AGQ9-1", "sequence": { "sequence": "MVQFRSSQPCQLPGSAADEQPQHCSALYNSPIVQPGAAARAVPRTKGDRDPAPRVPEPCAAFAHPAPIPLQPKAEAEAIEKELLEDYRFGRQQLIEMWGHACAVAVTKAFPLPSLPRKQPTVLVVCGPAQNGAIGLVCARHLRVFDYEPTIFYPKRSLDPLYRDFTTQCEKMDIPFLSYLPTEVQLINDAYNAVVDAVLGAEAELGEGRGPCAGILATLKHVRIPIVSLDVPSGWDVEAGSSGGISPDVLVSLMAPKQCARRFLGRQHFVAGRFVPYDVQKKFELNPPDYPGTECVVALRAPQ", "length": 303, "header": "tr|A0A8V1AGQ9-1|A0A8V1A946_CHICK Computationally mapped isoform of ApoA-I-binding protein 2 OS=Gallus gallus OX=9031 GN=YJEFN3 PE=4 SV=1 CANONICAL=A0A8V1A946-1" }, "locus": { "chromosome": "28", "start_pos": 3896885, "end_pos": 3893632, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069041.1", "url": "https://www.ensembl.org/id/ENSGALT00010069041.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042483.1", "url": "https://www.ensembl.org/id/ENSGALP00010042483.1" } ] } }, { "isoform_ac": "A0A8V1AKR9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A946/entry#A0A8V1AKR9-1", "sequence": { "sequence": "MSSVPGPSREPPRYLSKAEAEAIEKELLEDYRFGRQQLIEMWGHACAVAVTKAFPLPSLPRKQPTVLVVCGPAQNGAIGLVCARHLRVFDYEPTIFYPKRSLDPLYRDFTTQCEKMDIPFLSYLPTEVQLINDAYNAVVDAVLGAEAELGEGRGPCAGILATLKHVRIPIVSLDVPSGWDVEAGSSGGISPDVLVSLMAPKQCARRFLGRQHFVAGRFVPYDVQKKFELNPPDYPGTECVVALRAPQ", "length": 247, "header": "tr|A0A8V1AKR9-1|A0A8V1A946_CHICK Computationally mapped isoform of ApoA-I-binding protein 2 OS=Gallus gallus OX=9031 GN=YJEFN3 PE=4 SV=1 CANONICAL=A0A8V1A946-1" }, "locus": { "chromosome": "28", "start_pos": 3898813, "end_pos": 3893632, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069043.1", "url": "https://www.ensembl.org/id/ENSGALT00010069043.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042485.1", "url": "https://www.ensembl.org/id/ENSGALP00010042485.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:100857831", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100857831", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A946", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A946" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "NAD(P)HX epimerase activity", "id": "GO:0052856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0052856", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A946", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A946" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 3, "end_pos": 5, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1A946", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A946" }, { "id": "PS51385", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51385" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "YjeF N-terminal", "eco_id": "ECO_0000259", "start_pos": 95, "end_pos": 306, "start_aa": "Ala", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 3, "end_pos": 5 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A952-1", "uniprot_ac": "A0A8V1A952", "uniprot_id": "A0A8V1A952_CHICK", "mass": { "chemical_mass": 39862.0, "monoisotopic_mass": 39862.0 }, "refseq": {}, "gene_names": [ { "name": "FAM212A", "type": "recommended", "evidence": [ { "id": "A0A8V1A952", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A952" } ] } ], "protein_names": [ { "name": "Family with sequence similarity 212 member A", "type": "synonym", "evidence": [ { "id": "A0A8V1A952", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A952/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A952", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A952" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FAM212A", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A952", "locus": { "chromosome": "12", "start_pos": 2594525, "end_pos": 2589757, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010026901", "url": "https://www.ensembl.org/id/ENSGALG00010026901" } ] } } ], "crossref": [ { "id": "A0A8V1A952", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A952", "database": "AlphaFoldDB", "categories": [] }, { "id": "101751145", "url": "https://www.ncbi.nlm.nih.gov/gene/101751145", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR029267", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029267", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039201", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039201", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR28615", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28615", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR28615:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28615:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15342", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15342", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1A952", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A952", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A952-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A952-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AC14", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC14", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AC14-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC14-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "ESWSTPGVCLGGAGHRTACGAREGGDSAVSAGTRAHLGVLAGAEATIRRQHQALTGQSEWCATVSELELSEERSELHPSAWPSPGSAPFGRLQDRRQPALTISPPGGCARTAYRGARGATFADTHTTSPPALANFKSHRSACPDVTCTYSCPVTSCSPGQAARSISAYQFTRWASSSAPARSVTCAGTRRSLGTRCSAGCRVLQPRSLPRSSTSALNQWRALEPADGRDWTVSLLSQSRNRQPLVLGDNCFADLVENWMDLPEVGAEPRRRPPTEPSRRLGKPPAFLLSLSGNVRRKLASMARPRGAEGGRPGGRDPAKRLSCPLGLGGQPKGACFHQSHSNIAQLATDFHRFTALMNSRSRQPIICNDVIGYI", "length": 374, "header": "tr|A0A8V1A952-1|A0A8V1A952_CHICK Isoform 1 of Family with sequence similarity 212 member A OS=Gallus gallus OX=9031 GN=FAM212A PE=3 SV=1 CANONICAL=A0A8V1A952-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A952-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A952/entry#A0A8V1A952-1", "sequence": { "sequence": "ESWSTPGVCLGGAGHRTACGAREGGDSAVSAGTRAHLGVLAGAEATIRRQHQALTGQSEWCATVSELELSEERSELHPSAWPSPGSAPFGRLQDRRQPALTISPPGGCARTAYRGARGATFADTHTTSPPALANFKSHRSACPDVTCTYSCPVTSCSPGQAARSISAYQFTRWASSSAPARSVTCAGTRRSLGTRCSAGCRVLQPRSLPRSSTSALNQWRALEPADGRDWTVSLLSQSRNRQPLVLGDNCFADLVENWMDLPEVGAEPRRRPPTEPSRRLGKPPAFLLSLSGNVRRKLASMARPRGAEGGRPGGRDPAKRLSCPLGLGGQPKGACFHQSHSNIAQLATDFHRFTALMNSRSRQPIICNDVIGYI", "length": 374, "header": "tr|A0A8V1A952-1|A0A8V1A952_CHICK Isoform 1 of Family with sequence similarity 212 member A OS=Gallus gallus OX=9031 GN=FAM212A PE=3 SV=1 CANONICAL=A0A8V1A952-1" }, "locus": { "chromosome": "12", "start_pos": 2593521, "end_pos": 2589956, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065288.1", "url": "https://www.ensembl.org/id/ENSGALT00010065288.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039748.1", "url": "https://www.ensembl.org/id/ENSGALP00010039748.1" } ] } }, { "isoform_ac": "A0A8V1AC14-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A952/entry#A0A8V1AC14-1", "sequence": { "sequence": "MHSARLDGGLGQRRAEPRCRREHMPGTRPAERDPRPAPRRPGSACSEEEQGGPAARSPPASERSLECDSGYSEASGGTWREDEAPVLRRHPPPCQRAHRLSAGTPAPAPARRARPKSTSDACLEQWRALEPADGRDWTVSLLSQSRNRQPLVLGDNCFADLVENWMDLPEVGAEPRRRPPTEPSRRLGKPPAFLLSLSGNVRRKLASMARPRGAEGGRPGGRDPAKRLSCPLGLGGQPKGACFHQSHSNIAQLATDFHRFTALMNSRSRQPIICNDVIGYI", "length": 281, "header": "tr|A0A8V1AC14-1|A0A8V1AC14_CHICK Computationally mapped isoform of Family with sequence similarity 212 member A OS=Gallus gallus OX=9031 GN=FAM212A PE=3 SV=1 CANONICAL=A0A8V1A952-1" }, "locus": { "chromosome": "12", "start_pos": 2593521, "end_pos": 2591802, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065287.1", "url": "https://www.ensembl.org/id/ENSGALT00010065287.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039747.1", "url": "https://www.ensembl.org/id/ENSGALP00010039747.1" } ] } } ], "glycosylation": [], "phosphorylation": [], 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"publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A9A1-1", "uniprot_ac": "A0A8V1A9A1", "uniprot_id": "A0A8V1A9A1_CHICK", "mass": { "chemical_mass": 51650.0, "monoisotopic_mass": 51650.0 }, "refseq": { "ac": "NP_001013412", "name": "protein phosphatase 1M", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001013412" }, "gene_names": [ { "name": "PPM1M", "type": "recommended", "evidence": [ { "id": "A0A8V1A9A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9A1" } ] }, { "name": "PPM1M", "type": "synonym", "evidence": [ { "id": "NP_001013412", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001013412" } ] } ], "protein_names": [ { "name": "Protein phosphatase, Mg2+/Mn2+ dependent 1M", "type": "synonym", "evidence": [ { "id": "A0A8V1A9A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9A1/entry#names_and_taxonomy" } ] }, { "name": "protein phosphatase 1M (PP2C domain containing)", "type": "synonym", "evidence": [ { "id": "NP_001013412", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001013412" } ] }, { "name": "protein phosphatase 1M", "type": "synonym", "evidence": [ { "id": "NP_001013412", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001013412" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ719435.1, SRR13267655.17813.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000252.1. On Sep 23, 2021 this sequence version replaced NP_001013412.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001013412", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001013412" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9A1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9A1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PPM1M", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9A1", "locus": { "chromosome": "12", "start_pos": 3154844, "end_pos": 3148126, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027445", "url": "https://www.ensembl.org/id/ENSGALG00010027445" } ] } } ], "crossref": [ { "id": "A0A8V1A9A1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A9A1", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00143", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00143", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "415941", "url": "https://www.ncbi.nlm.nih.gov/gene/415941", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001932", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001932", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015655", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015655", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036457", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036457", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:415941", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415941", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CNKEVAH", "url": "https://omabrowser.org/oma/group/CNKEVAH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A9A1", "url": "https://www.orthodb.org/?gene=A0A8V1A9A1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13832", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13832", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13832:SF236", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13832:SF236", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00481", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00481", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001013412", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001013412", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1A9A1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9A1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A9A1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9A1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSVEWLRRLRRGGPAERPGGARESVPRSPQPAPPRYRRPKFLRGGEESPRGGRAVRGAGPERPLPWGSGYAEVINAEKSEFNEDQAACCQISVRRREPGLEEDQEWLILCSTQFLTGYYWALFDGHGGPEAAIIASDYLHYCIKQKLEEVAGAIVEARPPMHLSGRCVCDSDPQFVEEKHIHAEDVVVGALENAFQECDEVIGQEMEATNQTGGCTALAALYFQGKLYVANAGDSRAILILKDTVVPMSSEFTPETERQRLQHLAFLFPKLLDGEFTRFEFPRRLKGDDVGQKVLYRDYFMEGWGYKLVEKADLKYPLVHGHGKQARLLGTLSVSRGLGDHQLKVIDTNIEVKPFLSCIPKVNVFDFALHDIKEDDVLIMATDGLWDVLCNEEVAHMARSFLADNRTNPQRFSELAKSLACRARGKKRGHQWMLDDSQEASYDDISVFVIPLHNRVEDC", "length": 459, "header": "tr|A0A8V1A9A1-1|A0A8V1A9A1_CHICK Isoform 1 of Protein phosphatase, Mg2+/Mn2+ dependent 1M OS=Gallus gallus OX=9031 GN=PPM1M PE=4 SV=1 CANONICAL=A0A8V1A9A1-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A9A1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9A1/entry#A0A8V1A9A1-1", "sequence": { "sequence": "MSVEWLRRLRRGGPAERPGGARESVPRSPQPAPPRYRRPKFLRGGEESPRGGRAVRGAGPERPLPWGSGYAEVINAEKSEFNEDQAACCQISVRRREPGLEEDQEWLILCSTQFLTGYYWALFDGHGGPEAAIIASDYLHYCIKQKLEEVAGAIVEARPPMHLSGRCVCDSDPQFVEEKHIHAEDVVVGALENAFQECDEVIGQEMEATNQTGGCTALAALYFQGKLYVANAGDSRAILILKDTVVPMSSEFTPETERQRLQHLAFLFPKLLDGEFTRFEFPRRLKGDDVGQKVLYRDYFMEGWGYKLVEKADLKYPLVHGHGKQARLLGTLSVSRGLGDHQLKVIDTNIEVKPFLSCIPKVNVFDFALHDIKEDDVLIMATDGLWDVLCNEEVAHMARSFLADNRTNPQRFSELAKSLACRARGKKRGHQWMLDDSQEASYDDISVFVIPLHNRVEDC", "length": 459, "header": "tr|A0A8V1A9A1-1|A0A8V1A9A1_CHICK Isoform 1 of Protein phosphatase, Mg2+/Mn2+ dependent 1M OS=Gallus gallus OX=9031 GN=PPM1M PE=4 SV=1 CANONICAL=A0A8V1A9A1-1" }, "locus": { "chromosome": "12", "start_pos": 3153781, "end_pos": 3148176, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066527.1", "url": "https://www.ensembl.org/id/ENSGALT00010066527.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040751.1", "url": "https://www.ensembl.org/id/ENSGALP00010040751.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:415941", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415941", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0ABK0LDR0-1", "protein_name": "Protein phosphatase, Mg2+/Mn2+ dependent, 1M", "gene_name": "Ppm1m", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSAGWFRRRFLPGGPLPEPRPPGPRSSPVPYHRPRFLRGSGSSPGANDASRRPDARPVRSPARGRTLPWNAGYAEIINAEKSEFNEDQAACGKLCIRRCEFGIEEDQEWLTVCPEEFLTGHYWALFDGHGGPAAAILAANTLHSCLRRQLEVVVEGMMAAQPPMHLSGRCVCSSDPQFVEEKGIRAEDLVIGALENAFQECDDVIGRELEASGQVGGCTALVAVFLQGKLYVANAGDSRAILVRRDEIRLLSSEFTPETERQRIQQLAFTYPELLAGEFTRLEFPRRLKGDDLGQKVLFRDHHMRGWSYKQVEKTDLKYPLIHGQGRQARLLGTLAVSRGLGDHQLRVLDTDIQLKPFLLSIPQVTVLDVDQLALQEDDVVVMATDGLWDVLSNEQVALLVRSFLTGNREDPHRFSELAKMLIHNTQGKDGGASGEGQVSYDDVSVFVIPLSSQAQESGGH", "length": 461 }, "evidence": [ { "id": "A0A8V1A9A1", "url": "https://omabrowser.org/oma/group/A0A8V1A9A1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1SIX8-1", "protein_name": "Protein phosphatase, Mg2+/Mn2+ dependent 1M", "gene_name": "PPM1M", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSADWFRRRFLPGGPLTAPRPPRPRASPVPYRRPRFLRGSGSSTSTADASRRPDARPRPVRSPVRGRALPWNAGYAEIINAEKSEFNEDQAACGKLCIRRCGFGVEEDQEWLTLCPEEVLTGHYWALFDGHGGPAAAILAANTLHSCLRRQLEAVVDGMMATQPPMHLSGCCICPSDPQFVEEKGIRTEDLVIGALESAFQECDEVIGRELEASGQVGGCTALVAVSLQGKLYVANAGDSRAILVRRDEVRPLSSEFTPETERQRIQQLAFVYPELLAGEFTRLEFPRRLKGDDLGQKVLFRDHHMSGWSYKCVEKSDLKYPLIHGQGRQARLLGTLAVSRGLGDHQLRVLDTNIQLKPFLLSVPQVTVLDVDQLEPQEEDVVVMATDGLWDVLSNEQVAWLVRSFLPGNREDPHRFSELAQMLIHSTQGKDDSPTQEGQVSYDDVSVFVIPLHNHDQRRGSH", "length": 463 }, "evidence": [ { "id": "A0A8V1A9A1", "url": "https://omabrowser.org/oma/group/A0A8V1A9A1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q96MI6-5", "protein_name": "Protein phosphatase 1M", "gene_name": "PPM1M", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSAGWFRRRFLPGEPLPAPRPPGPHASPVPYRRPRFLRGSSSSPGAADASRRPDSRPVRSPARGRTLPWNAGYAEIINAEKSEFNEDQAACGKLCIRRCEFGAEEEWLTLCPEEFLTGHYWALFDGHGGPAAAILAANTLHSCLRRQLEAVVEGLVATQPPMHLNGRCICPSDPQFVEEKGIRAEDLVIGALESAFQECDEVIGRELEASGQMGGCTALVAVSLQGKLYMANAGDSRAILVRRDEIRPLSFEFTPETERQRIQQLAFVYPELLAGEFTRLEFPRRLKGDDLGQKVLFRDHHMSGWSYKRVEKSDLKYPLIHGQGRQARLLGTLAVSRGLGDHQLRVLDTNIQLKPFLLSVPQVTVLDVDQLELQEDDVVVMATDGLWDVLSNEQVAWLVRSFLPGNQEDPHRFSKLAQMLIHSTQGKEDSLTEEGQVSYDDVSVFVIPLHSQGQESSDH", "length": 459 }, "evidence": [ { "id": "A0A8V1A9A1", "url": "https://omabrowser.org/oma/group/A0A8V1A9A1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "[pyruvate dehydrogenase (acetyl-transferring)]-phosphatase activity", "id": "GO:0004741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004741", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9A1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9A1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9A1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9A1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 210, "end_pos": 212, "annotation": "n_glycosylation_sequon" }, { "start_pos": 405, "end_pos": 407, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1A9A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9A1" }, { "id": "PS51746", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51746" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PPM-type phosphatase", "eco_id": "ECO_0000259", "start_pos": 67, "end_pos": 452, "start_aa": "Gly", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 210, "end_pos": 212 }, { "start_pos": 405, "end_pos": 407 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A9A6-1", "uniprot_ac": "A0A8V1A9A6", "uniprot_id": "A0A8V1A9A6_CHICK", "mass": { "chemical_mass": 59266.0, "monoisotopic_mass": 59266.0 }, "refseq": { "ac": "XP_015155455", "name": "ADAMTS-like protein 5 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015155455" }, "gene_names": [ { "name": "ADAMTSL5", "type": "recommended", "evidence": [ { "id": "A0A8V1A9A6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9A6" } ] }, { "name": "ADAMTSL5", "type": "synonym", "evidence": [ { "id": "XP_015155455", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015155455" } ] } ], "protein_names": [ { "name": "ADAMTS like 5", "type": "synonym", "evidence": [ { "id": "A0A8V1A9A6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9A6/entry#names_and_taxonomy" } ] }, { "name": "ADAMTS-like protein 5 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015155455", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015155455" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052559.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015155455.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015155455", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015155455" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9A6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9A6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ADAMTSL5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9A6", "locus": { "chromosome": "28", "start_pos": 3676497, "end_pos": 3681163, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027448", "url": "https://www.ensembl.org/id/ENSGALG00010027448" } ] } } ], "crossref": [ { "id": "A0A8V1A9A6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A9A6", "database": "AlphaFoldDB", "categories": [] }, { "id": "427264", "url": "https://www.ncbi.nlm.nih.gov/gene/427264", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000884", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000884", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010294", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010294", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013273", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013273", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036383", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036383", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045371", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045371", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050439", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050439", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "CQSDFGE", "url": "https://omabrowser.org/oma/group/CQSDFGE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A9A6", "url": "https://www.orthodb.org/?gene=A0A8V1A9A6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13723", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13723", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13723:SF173", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13723:SF173", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00090", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00090", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF05986", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05986", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19236", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19236", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-5173214", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5173214", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015155455", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015155455", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1A9A6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9A6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A9A6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9A6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAVIGRRDGLAPRAHPGGPHGAGSWWPWRALLLAWLSLGCGIGTTQVPAPGEAMWGPEPPSRTRPRRQSAHGAWGSWGPWSACSSSCGDGVALRTRRCLRSAEEEPCIGDQRQYRLCQLQGCPGGSVPFRAMQCSLYDDTPVQGMQTRHRWVPFYGAPNVCDLNCLAVGHNFYYTFGRVLDGTRCRPGSTDLCVGGRCLSVGCDGILGTGAQPRVCSRCGGGQDGCLFVHRLFQDTEPFSGHFGYMNVTKIPAGATNIKVTDKSRNFLALMRSDGHYVLNGDWSIAWPGPYEVAGTQLLYARSPDGTESLEAPGPTDEDLHVLVLLQEPNPGIEYEFWLPRGHPQHSMVDTSALRQPQPRGAGSPPPAEPPLPTVPPRARDPITEPLPPRSPPGVRSAAGRCGRCHPPKGRSQRIRHFCQSDFGEQRVPSTDPGAALGGAGDALRGAGGDAVPAPLPHGTTGVRLGARHVRLPHAAGGPRLRADGTAPRQLRAHVEPHPAATRRLRTALVTPRGARGAGRGTALCPPALSQQGWGTPWGMGMMQGWGTPPAVLGAL", "length": 556, "header": "tr|A0A8V1A9A6-1|A0A8V1A9A6_CHICK Isoform 1 of ADAMTS like 5 OS=Gallus gallus OX=9031 GN=ADAMTSL5 PE=4 SV=1 CANONICAL=A0A8V1A9A6-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A9A6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9A6/entry#A0A8V1A9A6-1", "sequence": { "sequence": "MAVIGRRDGLAPRAHPGGPHGAGSWWPWRALLLAWLSLGCGIGTTQVPAPGEAMWGPEPPSRTRPRRQSAHGAWGSWGPWSACSSSCGDGVALRTRRCLRSAEEEPCIGDQRQYRLCQLQGCPGGSVPFRAMQCSLYDDTPVQGMQTRHRWVPFYGAPNVCDLNCLAVGHNFYYTFGRVLDGTRCRPGSTDLCVGGRCLSVGCDGILGTGAQPRVCSRCGGGQDGCLFVHRLFQDTEPFSGHFGYMNVTKIPAGATNIKVTDKSRNFLALMRSDGHYVLNGDWSIAWPGPYEVAGTQLLYARSPDGTESLEAPGPTDEDLHVLVLLQEPNPGIEYEFWLPRGHPQHSMVDTSALRQPQPRGAGSPPPAEPPLPTVPPRARDPITEPLPPRSPPGVRSAAGRCGRCHPPKGRSQRIRHFCQSDFGEQRVPSTDPGAALGGAGDALRGAGGDAVPAPLPHGTTGVRLGARHVRLPHAAGGPRLRADGTAPRQLRAHVEPHPAATRRLRTALVTPRGARGAGRGTALCPPALSQQGWGTPWGMGMMQGWGTPPAVLGAL", "length": 556, "header": "tr|A0A8V1A9A6-1|A0A8V1A9A6_CHICK Isoform 1 of ADAMTS like 5 OS=Gallus gallus OX=9031 GN=ADAMTSL5 PE=4 SV=1 CANONICAL=A0A8V1A9A6-1" }, "locus": { "chromosome": "28", "start_pos": 3681047, "end_pos": 3676634, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066536.1", "url": "https://www.ensembl.org/id/ENSGALT00010066536.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040756.1", "url": "https://www.ensembl.org/id/ENSGALP00010040756.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 316, "start_aa": "Thr", "end_pos": 316, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr316", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 374, "start_aa": "Thr", "end_pos": 374, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr374", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-GGA-5173214", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5173214", "resource": "Reactome", "description": "O-glycosylation of TSR domain-containing proteins" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9A6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9A6" } ], "pmid": "" }, { "name": "extracellular matrix", "id": "GO:0031012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031012", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9A6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9A6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "extracellular matrix organization", "id": "GO:0030198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030198", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9A6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9A6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 247, "end_pos": 249, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1A9A6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9A6" }, { "id": "PF05986", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05986" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "ADAMTS/ADAMTS-like Spacer 1", "eco_id": "ECO_0000259", "start_pos": 242, "end_pos": 340, "start_aa": "His", "end_aa": "Pro", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1A9A6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9A6" }, { "id": "PF19236", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19236" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "ADAMTS/ADAMTS-like cysteine-rich", "eco_id": "ECO_0000259", "start_pos": 152, "end_pos": 226, "start_aa": "Val", "end_aa": "Cys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 316, 374 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 247, "end_pos": 249 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A9C8-1", "uniprot_ac": "A0A8V1A9C8", "uniprot_id": "A0A8V1A9C8_CHICK", "mass": { "chemical_mass": 7588.0, "monoisotopic_mass": 7588.0 }, "refseq": {}, "gene_names": [ { "name": "PCP4L1", "type": "recommended", "evidence": [ { "id": "A0A8V1A9C8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9C8" } ] } ], "protein_names": [ { "name": "Purkinje cell protein 4 like 1", "type": "synonym", "evidence": [ { "id": "A0A8V1A9C8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9C8/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9C8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9C8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PCP4L1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9C8", "locus": { "chromosome": "25", "start_pos": 2486286, "end_pos": 2487531, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027492", "url": "https://www.ensembl.org/id/ENSGALG00010027492" } ] } } ], "crossref": [ { "id": "A0A8V1A9C8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A9C8", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR052142", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052142", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR15359", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15359", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15359:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15359:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A9C8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9C8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A9C8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9C8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "PQRSPDASPRPTETPGGQQEAKAADPKRGEEEEEEIDIDLSAPETERAALSIQGRFRRFQKRKKESGP", "length": 68, "header": "tr|A0A8V1A9C8-1|A0A8V1A9C8_CHICK Isoform 1 of Purkinje cell protein 4 like 1 OS=Gallus gallus OX=9031 GN=PCP4L1 PE=3 SV=1 CANONICAL=A0A8V1A9C8-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A9C8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9C8/entry#A0A8V1A9C8-1", "sequence": { "sequence": "PQRSPDASPRPTETPGGQQEAKAADPKRGEEEEEEIDIDLSAPETERAALSIQGRFRRFQKRKKESGP", "length": 68, "header": "tr|A0A8V1A9C8-1|A0A8V1A9C8_CHICK Isoform 1 of Purkinje cell protein 4 like 1 OS=Gallus gallus OX=9031 GN=PCP4L1 PE=3 SV=1 CANONICAL=A0A8V1A9C8-1" }, "locus": { "chromosome": "25", "start_pos": 2487531, "end_pos": 2486711, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066601.1", "url": "https://www.ensembl.org/id/ENSGALT00010066601.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040783.1", "url": "https://www.ensembl.org/id/ENSGALP00010040783.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], 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0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A9E3-1", "uniprot_ac": "A0A8V1A9E3", "uniprot_id": "A0A8V1A9E3_CHICK", "mass": { "chemical_mass": 127244.0, "monoisotopic_mass": 127244.0 }, "refseq": {}, "gene_names": [ { "name": "MYO1F", "type": "recommended", "evidence": [ { "id": "A0A8V1A9E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9E3" } ] } ], "protein_names": [ { "name": "Myosin IF", "type": "synonym", "evidence": [ { "id": "A0A8V1A9E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9E3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9E3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9E3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MYO1F", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9E3", "locus": { "chromosome": "28", "start_pos": 2170072, "end_pos": 2183246, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028548", "url": "https://www.ensembl.org/id/ENSGALG00010028548" } ] } } ], "crossref": [ { "id": "A0A8V1A9E3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A9E3", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd01378", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01378", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd11827", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11827", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001609", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001609", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010926", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010926", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035507", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035507", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036028", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036028", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036072", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036072", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A9E3", "url": "https://www.orthodb.org/?gene=A0A8V1A9E3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AEK6", "url": "https://www.orthodb.org/?gene=A0A8V1AEK6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AGZ8", "url": "https://www.orthodb.org/?gene=A0A8V1AGZ8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AJ75", "url": "https://www.orthodb.org/?gene=A0A8V1AJ75", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13140", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13140", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13140:SF663", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13140:SF663", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00063", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00063", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF06017", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06017", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14604", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14604", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1A9E3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9E3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A9E3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9E3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AEK6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEK6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AEK6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEK6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGZ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGZ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGZ8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJ75", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ75", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJ75-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ75-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPRSQGQDTGTPCKERFHWQSHNVKQSGVDDMVLLAKISEEAIVENLKKRFMDDYIFTYIGPVLISVNPFKQMPYFTDREIELYQGAAQYENPPHIYALTDNMYRNMLIDGENQCVIISGESGAGKTVAAKYIMGYISKVSGGGDKVQHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSRGGEPDGGKISNFLLEKSRVVSQNEHERNFHVYYQLIEGASQEQRQNLGIMSPDYYYYLNQSDTYQVEGTDDRSDFLETMNAMQVIGIRGEDQQLVLQIVAGILHLGNISFREEGNYARVENADSLAFPAYLLGIDRDRLNDKITSRKMDSKWGGRSESITVTLNVEQAAYTRDALAKGLYARVFDFLVESINRAMQKPYEEYSIGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLKAEQEEYVQEGIKWTQIQYFNNKVVCDLIENKLNPPGIMSVLDDVCATMHATGEGADQTLLQKLQAAVGTHEHFNSWSSGFVIHHYAGKVSYDVNGFCERNRDVLFTDLIELMQSSEYAFIRMLFPEKLDADKKGRPTTAGSKIKKQANDLVNTLMKCTPHYIRCIKPNETKKPRDWEESRVKHQVEYLGLKENIRVRRAGFAYRRIFHKFLQRYAILTPETWPSWRGDERQGVQHLLRSVNMDPDQYQMGRSKVFVKNPESLFLLEEMRERKFDGFARVIQKAWRRHIAIRKYEQMREEASSILYNFKERRRNSINRNFVGDYLGMEERPELRQFLAKRERIDFADSITKYDRRFKPIKRDFILTPKYFYLIGREKVKKGPEKGQIKEVLKKKVEIQAVSGVSLSTRQDDFFILHEKDADNFLESIFKTELVSLLCKRYEELTRSKLRLNFQDTLQFRVKKEGWGGGGTRTVTFTRGQGDVAALKAGGKTLTVSIADGLPRNSKPTRKEVMQSKGGSRRPPPSRGVPPAPQGTYRNGAPQFPRGDGHAKRDTYTTPQKQARAPPATALPPQNASRRSKARPPSEQNMEFLNVPDQGVAGMQRRRSVGQRPPPASRPKPQPKAAVPRCQALYQYIGQDVDELSFNVGDVIDILLEDISGWWKGRLHGREGLFPGNYVQKI", "length": 1109, "header": "tr|A0A8V1A9E3-1|A0A8V1A9E3_CHICK Isoform 1 of Myosin IF OS=Gallus gallus OX=9031 GN=MYO1F PE=1 SV=1 CANONICAL=A0A8V1A9E3-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A9E3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9E3/entry#A0A8V1A9E3-1", "sequence": { "sequence": "MPRSQGQDTGTPCKERFHWQSHNVKQSGVDDMVLLAKISEEAIVENLKKRFMDDYIFTYIGPVLISVNPFKQMPYFTDREIELYQGAAQYENPPHIYALTDNMYRNMLIDGENQCVIISGESGAGKTVAAKYIMGYISKVSGGGDKVQHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSRGGEPDGGKISNFLLEKSRVVSQNEHERNFHVYYQLIEGASQEQRQNLGIMSPDYYYYLNQSDTYQVEGTDDRSDFLETMNAMQVIGIRGEDQQLVLQIVAGILHLGNISFREEGNYARVENADSLAFPAYLLGIDRDRLNDKITSRKMDSKWGGRSESITVTLNVEQAAYTRDALAKGLYARVFDFLVESINRAMQKPYEEYSIGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLKAEQEEYVQEGIKWTQIQYFNNKVVCDLIENKLNPPGIMSVLDDVCATMHATGEGADQTLLQKLQAAVGTHEHFNSWSSGFVIHHYAGKVSYDVNGFCERNRDVLFTDLIELMQSSEYAFIRMLFPEKLDADKKGRPTTAGSKIKKQANDLVNTLMKCTPHYIRCIKPNETKKPRDWEESRVKHQVEYLGLKENIRVRRAGFAYRRIFHKFLQRYAILTPETWPSWRGDERQGVQHLLRSVNMDPDQYQMGRSKVFVKNPESLFLLEEMRERKFDGFARVIQKAWRRHIAIRKYEQMREEASSILYNFKERRRNSINRNFVGDYLGMEERPELRQFLAKRERIDFADSITKYDRRFKPIKRDFILTPKYFYLIGREKVKKGPEKGQIKEVLKKKVEIQAVSGVSLSTRQDDFFILHEKDADNFLESIFKTELVSLLCKRYEELTRSKLRLNFQDTLQFRVKKEGWGGGGTRTVTFTRGQGDVAALKAGGKTLTVSIADGLPRNSKPTRKEVMQSKGGSRRPPPSRGVPPAPQGTYRNGAPQFPRGDGHAKRDTYTTPQKQARAPPATALPPQNASRRSKARPPSEQNMEFLNVPDQGVAGMQRRRSVGQRPPPASRPKPQPKAAVPRCQALYQYIGQDVDELSFNVGDVIDILLEDISGWWKGRLHGREGLFPGNYVQKI", "length": 1109, "header": "tr|A0A8V1A9E3-1|A0A8V1A9E3_CHICK Isoform 1 of Myosin IF OS=Gallus gallus OX=9031 GN=MYO1F PE=1 SV=1 CANONICAL=A0A8V1A9E3-1" }, "locus": { "chromosome": "28", "start_pos": 2183154, "end_pos": 2170381, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069143.1", "url": "https://www.ensembl.org/id/ENSGALT00010069143.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042585.1", "url": "https://www.ensembl.org/id/ENSGALP00010042585.1" } ] } }, { "isoform_ac": "A0A8V1AEK6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9E3/entry#A0A8V1AEK6-1", "sequence": { "sequence": "MGSKERFHWQSHNVKQSGVDDMVLLAKISEEAIVENLKKRFMDDYIFTYIGPVLISVNPFKQMPYFTDREIELYQGAAQYENPPHIYALTDNMYRNMLIDGENQCVIISGESGAGKTVAAKYIMGYISKVSGGGDKVQHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSRGGEPDGGKISNFLLEKSRVVSQNEHERNFHVYYQLIEGASQEQRQNLGIMSPDYYYYLNQSDTYQVEGTDDRSDFLETMNAMQVIGIRGEDQQLVLQIVAGILHLGNISFREEGNYARVENADSLAFPAYLLGIDRDRLNDKITSRKMDSKWGGRSESITVTLNVEQAAYTRDALAKGLYARVFDFLVESINRAMQKPYEEYSIGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLKAEQEEYVQEGIKWTQIQYFNNKVVCDLIENKLNPPGIMSVLDDVCATMHATGEGADQTLLQKLQAAVGTHEHFNSWSSGFVIHHYAGKVSYDVNGFCERNRDVLFTDLIELMQSSEYAFIRMLFPEKLDADKKGRPTTAGSKIKKQANDLVNTLMKCTPHYIRCIKPNETKKPRDWEESRVKHQVEYLGLKENIRVRRAGFAYRRIFHKFLQRYAILTPETWPSWRGDERQGVQHLLRSVNMDPDQYQMGRSKVFVKNPESLFLLEEMRERKFDGFARVIQKAWRRHIAIRKYEQMREEASSILYNFKERRRNSINRNFVGDYLGMEERPELRQFLAKRERIDFADSITKYDRRFKPIKRDFILTPKYFYLIGREKVKKGPEKGQIKEVLKKKVEIQAVSGVSLSTRQDDFFILHEKDADNFLESIFKTELVSLLCKRYEELTRSKLRLNFQDTLQFRVKKEGWGGGGTRTVTFTRGQGDVAALKAGGKTLTVSIADGLPRNSKPTRKEVMQSKGGSRRPPPSRGVPPAPQGTYRNGAPQFPRGDGHAKRDTYTTPQKQARAPPATALPPQNASRRSKARPPSEQNMEFLNVPDQGVAG", "length": 1019, "header": "tr|A0A8V1AEK6-1|A0A8V1AEK6_CHICK Computationally mapped isoform of Myosin IF OS=Gallus gallus OX=9031 GN=MYO1F PE=1 SV=1 CANONICAL=A0A8V1A9E3-1" }, "locus": { "chromosome": "28", "start_pos": 2183119, "end_pos": 2171290, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069140.1", "url": "https://www.ensembl.org/id/ENSGALT00010069140.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042582.1", "url": "https://www.ensembl.org/id/ENSGALP00010042582.1" } ] } }, { "isoform_ac": "A0A8V1AGZ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9E3/entry#A0A8V1AGZ8-1", "sequence": { "sequence": "MGSKERFHWQSHNVKQSGVDDMVLLAKISEEAIVENLKKRFMDDYIFTYIGPVLISVNPFKQMPYFTDREIELYQGAAQYENPPHIYALTDNMYRNMLIDGENQCVIIRAAPRVGVPAPPPAPWGSCSECRHVVLLTFMPCSGHQHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSRGGEPDGGKISNFLLEKSRVVSQNEHERNFHVYYQLIEGASQEQRQNLGIMSPDYYYYLNQSDTYQVEGTDDRSDFLETMNAMQVIGIRGEDQQLVLQIVAGILHLGNISFREEGNYARVENADSLAFPAYLLGIDRDRLNDKITSRKMDSKWGGRSESITVTLNVEQAAYTRDALAKGLYARVFDFLVESINRAMQKPYEEYSIGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLKAEQEEYVQEGIKWTQIQYFNNKVVCDLIENKLNPPGIMSVLDDVCATMHATGEGADQTLLQKLQAAVGTHEHFNSWSSGFVIHHYAGKVSYDVNGFCERNRDVLFTDLIELMQSSEYAFIRMLFPEKLDADKKGRPTTAGSKIKKQANDLVNTLMKCTPHYIRCIKPNETKKPRDWEESRVKHQVEYLGLKENIRVRRAGFAYRRIFHKFLQRYAILTPETWPSWRGDERQGVQHLLRSVNMDPDQYQMGRSKVFVKNPESLFLLEEMRERKFDGFARVIQKAWRRHIAIRKYEQMREEASSILYNFKERRRNSINRNFVGDYLGMEERPELRQFLAKRERIDFADSITKYDRRFKPIKRDFILTPKYFYLIGREKVKKGPEKGQIKEVLKKKVEIQAVSGVSLSTRQDDFFILHEKDADNFLESIFKTELVSLLCKRYEELTRSKLRLNFQDTLQFRVKKEGWGGGGTRTVTFTRGQGDVAALKAGGKTLTVSIADGLPRNSKPTRKEVMQSKGGSRRPPPSRGVPPAPQGTYRNGAPQFPRGDGHAKRDTYTTPQKQARAPPATALPPQNASRRSKARPPSEQNMEFLNVPDQGVAGMQRRRSVGQRPPPASRPKPQPKAAVPRCQALYQYIGQDVDELSFNVGDVIDILLEDISGWWKGRLHGREGLFPGNYVQKI", "length": 1106, "header": "tr|A0A8V1AGZ8-1|A0A8V1A9E3_CHICK Computationally mapped isoform of Myosin IF OS=Gallus gallus OX=9031 GN=MYO1F PE=1 SV=1 CANONICAL=A0A8V1A9E3-1" }, "locus": { "chromosome": "28", "start_pos": 2183119, "end_pos": 2170381, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069142.1", "url": "https://www.ensembl.org/id/ENSGALT00010069142.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042584.1", "url": "https://www.ensembl.org/id/ENSGALP00010042584.1" } ] } }, { "isoform_ac": "A0A8V1AJ75-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9E3/entry#A0A8V1AJ75-1", "sequence": { "sequence": 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"length": 1109, "header": "tr|A0A8V1AJ75-1|A0A8V1A9E3_CHICK Computationally mapped isoform of Myosin IF OS=Gallus gallus OX=9031 GN=MYO1F PE=1 SV=1 CANONICAL=A0A8V1A9E3-1" }, "locus": { "chromosome": "28", "start_pos": 2183119, "end_pos": 2170184, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069141.1", "url": "https://www.ensembl.org/id/ENSGALT00010069141.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042583.1", "url": "https://www.ensembl.org/id/ENSGALP00010042583.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "calmodulin binding", "id": "GO:0005516", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005516", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9E3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9E3" } ], "pmid": "" }, { 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"phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": 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"phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A9G1-1", "uniprot_ac": "A0A8V1A9G1", "uniprot_id": "A0A8V1A9G1_CHICK", "mass": { "chemical_mass": 24213.0, "monoisotopic_mass": 24213.0 }, "refseq": { "ac": "NP_990343", "name": "homeobox protein ANF-1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990343" }, "gene_names": [ { "name": "HESX1", "type": "recommended", "evidence": [ { "id": "A0A8V1A9G1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9G1" } ] }, { "name": "GANF", "type": "synonym", "evidence": [ { "id": "NP_990343", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990343" } ] }, { "name": "HESX1", "type": "synonym", "evidence": [ { "id": "NP_990343", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990343" } ] } ], "protein_names": [ { "name": "HESX homeobox 1", "type": "synonym", "evidence": [ { "id": "A0A8V1A9G1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9G1/entry#names_and_taxonomy" } ] }, { "name": "anterior neural fold protein", "type": "synonym", "evidence": [ { "id": "NP_990343", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990343" } ] }, { "name": "homeo box (expressed in ES cells) 1", "type": "synonym", "evidence": [ { "id": "NP_990343", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990343" } ] }, { "name": "homeobox protein ANF-1", "type": "synonym", "evidence": [ { "id": "NP_990343", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990343" } ] }, { "name": "homeobox protein GANF", "type": "synonym", "evidence": [ { "id": "NP_990343", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990343" } ] }, { "name": "homeobox, ES cell expressed 1", "type": "synonym", "evidence": [ { "id": "NP_990343", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990343" } ] }, { "name": "homeodomain-containing protein", "type": "synonym", "evidence": [ { "id": "NP_990343", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990343" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: CR352461.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000252.1. On Dec 3, 2021 this sequence version replaced NP_990343.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_990343", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990343" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9G1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9G1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "HESX1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9G1", "locus": { "chromosome": "12", "start_pos": 8781787, "end_pos": 8791258, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027046", "url": "https://www.ensembl.org/id/ENSGALG00010027046" } ] } } ], "crossref": [ { "id": "A0A8V1A9G1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A9G1", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00086", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00086", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "395864", "url": "https://www.ncbi.nlm.nih.gov/gene/395864", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001356", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001356", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017970", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017970", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043402", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043402", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:395864", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395864", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VNLCVHI", "url": "https://omabrowser.org/oma/group/VNLCVHI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A9G1", "url": "https://www.orthodb.org/?gene=A0A8V1A9G1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46966", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46966", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46966:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46966:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00046", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00046", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_990343", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990343", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1A9G1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9G1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A9G1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9G1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MCCAVLAEGETMASTSLCAANPSASQNLRKVSGFVENKTTQCSFSIESILGLEQKKDGIAAVKPHRPWMDVCTNLVLGDDSDPHLQIPVVSYENSLFHANSNLMQEEKVLNCEKYFSVTERLSFKRELSWYRGRRPRTAFTRNQIEVLENVFKMNSYPGIDIREELARKLDLEEDRIQIWFQNRRAKLKRSHRESQFLMVKNNFTSSLLE", "length": 210, "header": "tr|A0A8V1A9G1-1|A0A8V1A9G1_CHICK Isoform 1 of HESX homeobox 1 OS=Gallus gallus OX=9031 GN=HESX1 PE=3 SV=1 CANONICAL=A0A8V1A9G1-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A9G1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9G1/entry#A0A8V1A9G1-1", "sequence": { "sequence": "MCCAVLAEGETMASTSLCAANPSASQNLRKVSGFVENKTTQCSFSIESILGLEQKKDGIAAVKPHRPWMDVCTNLVLGDDSDPHLQIPVVSYENSLFHANSNLMQEEKVLNCEKYFSVTERLSFKRELSWYRGRRPRTAFTRNQIEVLENVFKMNSYPGIDIREELARKLDLEEDRIQIWFQNRRAKLKRSHRESQFLMVKNNFTSSLLE", "length": 210, "header": "tr|A0A8V1A9G1-1|A0A8V1A9G1_CHICK Isoform 1 of HESX homeobox 1 OS=Gallus gallus OX=9031 GN=HESX1 PE=3 SV=1 CANONICAL=A0A8V1A9G1-1" }, "locus": { "chromosome": "12", "start_pos": 8784280, "end_pos": 8782324, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065575.1", "url": "https://www.ensembl.org/id/ENSGALT00010065575.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039866.1", "url": "https://www.ensembl.org/id/ENSGALP00010039866.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:395864", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395864", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3L7GV18-1", "protein_name": "Homeobox expressed in ES cells 1", "gene_name": "Hesx1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSPSLQEGAQLGESKPSSCSFSIESILGLDQKKDCVPSLRPHRPWADTCGDSEKYGNLCLHDPDLPSEISFPCLVDHPMPEERASKHENYFSTSETLPLKRELSWYRGRRPRTAFTQNQVEVLENVFRVNCYPGIDIREDLAQKLNLEEDRIQIWFQNRRAKLKRSRRESQFLMAKKKTFNTDLLK", "length": 186 }, "evidence": [ { "id": "A0A8V1A9G1", "url": "https://omabrowser.org/oma/group/A0A8V1A9G1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "D4AEG9-1", "protein_name": "Homeobox expressed in ES cells 1", "gene_name": "Hesx1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSPSLREVAQLRESKPSPCSFSIESILGLDQKKDCATSVRPHRPWTDTCGDSEKDGNPRLHAPGLPSEISFPCPVDHPMPEERAPKYENYFSASETHSLKRELSWYRGRRPRTAFTQNQVEVLENVFRMNCYPGIDIREDLAQKLNLEEDRIQIWFQNRRAKLKRSRRESQFLMAKKPFNPDLLK", "length": 185 }, "evidence": [ { "id": "A0A8V1A9G1", "url": "https://omabrowser.org/oma/group/A0A8V1A9G1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "I3LKM5-1", "protein_name": "Homeobox expressed in ES cells 1", "gene_name": "HESX1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSPSLQEGARLAESKPSPCSFSIESILGLDQKKDCVPSTKPHRPWADTCSSSGKDVNFCLHVPSLPDGISLPCNVDHSVPEEGVLKCENYFSASERLSLKRELSWYRGRRPRTAFTQNQIEMLENVFRVNCYPGIDIREDLARKLNLEEDRIQIWFQNRRAKLKRSHRESQFLMAKKSFNTDLLE", "length": 185 }, "evidence": [ { "id": "A0A8V1A9G1", "url": "https://omabrowser.org/oma/group/A0A8V1A9G1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q61658-1", "protein_name": "Homeobox expressed in ES cells 1", "gene_name": "Hesx1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSPSLREGAQLRESKPAPCSFSIESILGLDQKKDCTTSVRPHRPWTDTCGDSEKGGNPPLHAPDLPSETSFPCPVDHPRPEERAPKYENYFSASETRSLKRELSWYRGRRPRTAFTQNQVEVLENVFRVNCYPGIDIREDLAQKLNLEEDRIQIWFQNRRAKMKRSRRESQFLMAKKPFNPDLLK", "length": 185 }, "evidence": [ { "id": "A0A8V1A9G1", "url": "https://omabrowser.org/oma/group/A0A8V1A9G1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9UBX0-1", "protein_name": "Homeobox expressed in ES cells 1", "gene_name": "HESX1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSPSLQEGAQLGENKPSTCSFSIERILGLDQKKDCVPLMKPHRPWADTCSSSGKDGNLCLHVPNPPSGISFPSVVDHPMPEERASKYENYFSASERLSLKRELSWYRGRRPRTAFTQNQIEVLENVFRVNCYPGIDIREDLAQKLNLEEDRIQIWFQNRRAKLKRSHRESQFLMAKKNFNTNLLE", "length": 185 }, "evidence": [ { "id": "A0A8V1A9G1", "url": "https://omabrowser.org/oma/group/A0A8V1A9G1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9G1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9G1" } ], "pmid": "" }, { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9G1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9G1" } ], "pmid": "" }, { "name": "DNA-binding transcription repressor activity, RNA polymerase II-specific", "id": "GO:0001227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001227", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9G1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9G1" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9G1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9G1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9G1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9G1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9G1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9G1" } ], "pmid": "" }, { "name": "pituitary gland development", "id": "GO:0021983", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021983", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9G1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9G1" } ], "pmid": "" } ] } ] }, 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"sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A9K9-1", "uniprot_ac": "A0A8V1A9K9", "uniprot_id": "A0A8V1A9K9_CHICK", "mass": { "chemical_mass": 19540.0, "monoisotopic_mass": 19540.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Occludin/ELL domain containing 1", "type": "synonym", "evidence": [ { "id": "A0A8V1A9K9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9K9/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9K9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9K9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9K9", "locus": {} } ], "crossref": [ { "id": "A0A8V1A9K9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A9K9", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR010844", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010844", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031176", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031176", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A9K9", "url": "https://www.orthodb.org/?gene=A0A8V1A9K9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23288", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23288", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23288:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23288:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A9K9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9K9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A9K9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9K9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFNPRCQSEAGSGSAPGGPRPAMQQAVCVPKPLLVQAKRVVFEDEVGMAGRPPQRARLTTTEEGERWGGSGSVPQPRSIPDYVVRYPAIRSAQQRQRYGAVFADQHAEYRQLRGQLRAEQRGDAVRPLHRRVGTDLAFVAKWQRCLYLKEKLTHIKAQIHEYDRSSDRSAVRF", "length": 173, "header": "tr|A0A8V1A9K9-1|A0A8V1A9K9_CHICK Isoform 1 of Occludin/ELL domain containing 1 OS=Gallus gallus OX=9031 GN= PE=3 SV=1 CANONICAL=A0A8V1A9K9-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A9K9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9K9/entry#A0A8V1A9K9-1", "sequence": { "sequence": "MFNPRCQSEAGSGSAPGGPRPAMQQAVCVPKPLLVQAKRVVFEDEVGMAGRPPQRARLTTTEEGERWGGSGSVPQPRSIPDYVVRYPAIRSAQQRQRYGAVFADQHAEYRQLRGQLRAEQRGDAVRPLHRRVGTDLAFVAKWQRCLYLKEKLTHIKAQIHEYDRSSDRSAVRF", "length": 173, "header": "tr|A0A8V1A9K9-1|A0A8V1A9K9_CHICK Isoform 1 of Occludin/ELL domain containing 1 OS=Gallus gallus OX=9031 GN= PE=3 SV=1 CANONICAL=A0A8V1A9K9-1" }, "locus": { "chromosome": "28", "start_pos": 3808129, "end_pos": 3806369, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069209.1", "url": "https://www.ensembl.org/id/ENSGALT00010069209.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042651.1", "url": "https://www.ensembl.org/id/ENSGALP00010042651.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1A9K9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9K9" }, { "id": "PS51980", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51980" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "OCEL", "eco_id": "ECO_0000259", "start_pos": 80, "end_pos": 173, "start_aa": "Pro", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A9L3-1", "uniprot_ac": "A0A8V1A9L3", "uniprot_id": "A0A8V1A9L3_CHICK", "mass": { "chemical_mass": 45677.0, "monoisotopic_mass": 45677.0 }, "refseq": { "ac": "XP_003642731", "name": "exopolyphosphatase PRUNE1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642731" }, "gene_names": [ { "name": "PRUNE1", "type": "recommended", "evidence": [ { "id": "A0A8V1A9L3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9L3" } ] }, { "name": "PRUNE1", "type": "synonym", "evidence": [ { "id": "XP_003642731", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642731" } ] } ], "protein_names": [ { "name": "Prune exopolyphosphatase 1", "type": "synonym", "evidence": [ { "id": "A0A8V1A9L3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9L3/entry#names_and_taxonomy" } ] }, { "name": "exopolyphosphatase PRUNE1", "type": "synonym", "evidence": [ { "id": "XP_003642731", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642731" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052556.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_003642731.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003642731", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642731" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9L3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9L3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PRUNE1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9L3", "locus": { "chromosome": "25", "start_pos": 2606944, "end_pos": 2594753, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028580", "url": "https://www.ensembl.org/id/ENSGALG00010028580" } ] } } ], "crossref": [ { "id": "A0A8V1A9L3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A9L3", "database": "AlphaFoldDB", "categories": [] }, { "id": "427053", "url": "https://www.ncbi.nlm.nih.gov/gene/427053", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004097", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004097", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038222", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038222", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038763", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038763", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:427053", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427053", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TMTIFFN", "url": "https://omabrowser.org/oma/group/TMTIFFN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A9L3", "url": "https://www.orthodb.org/?gene=A0A8V1A9L3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AL67", "url": "https://www.orthodb.org/?gene=A0A8V1AL67", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12112", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12112", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12112:SF47", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12112:SF47", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02833", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02833", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003642731", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642731", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1A9L3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9L3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A9L3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9L3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AL67", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL67", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AL67-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL67-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MERFLGGRRAALQEHIQRRQEVHVVMGNEACDLDSTVSALALAYFLAKTSVPPKAAFIPVLNIPRADFALRTETTFLLREHSIPDSSLIFRDEIDLAGLHRAGLLSLTLVDHHVLPSTDAALEEAVVDVLDHRPLEREWAPSCQLTVELVGSCATLVTERIAQGPPGVLDRTTAALLHGTILLDSVNLSPAAGKVTPRDVLCVSLLESRFPELPPHDSIYGALQAAKFDVSGLTTEQMLRKDLKTVSGDEQVLAISGVYMDIELFLRRPGLLQDLETFCQTRGYSVLVAMTVSFNDCYEPTRQLAVYSQHEALRSTVCRALEEATTPALHLQALPSPWPCISAYAQGNTLASRKKVLPILRAALGGGPGTAAGPEEEAAPPPTPMNSLVEESPLAQAVPPVCPQAVLERVSRMAAEQPDSDK", "length": 422, "header": "tr|A0A8V1A9L3-1|A0A8V1A9L3_CHICK Isoform 1 of Prune exopolyphosphatase 1 OS=Gallus gallus OX=9031 GN=PRUNE1 PE=1 SV=1 CANONICAL=A0A8V1A9L3-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A9L3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9L3/entry#A0A8V1A9L3-1", "sequence": { "sequence": "MERFLGGRRAALQEHIQRRQEVHVVMGNEACDLDSTVSALALAYFLAKTSVPPKAAFIPVLNIPRADFALRTETTFLLREHSIPDSSLIFRDEIDLAGLHRAGLLSLTLVDHHVLPSTDAALEEAVVDVLDHRPLEREWAPSCQLTVELVGSCATLVTERIAQGPPGVLDRTTAALLHGTILLDSVNLSPAAGKVTPRDVLCVSLLESRFPELPPHDSIYGALQAAKFDVSGLTTEQMLRKDLKTVSGDEQVLAISGVYMDIELFLRRPGLLQDLETFCQTRGYSVLVAMTVSFNDCYEPTRQLAVYSQHEALRSTVCRALEEATTPALHLQALPSPWPCISAYAQGNTLASRKKVLPILRAALGGGPGTAAGPEEEAAPPPTPMNSLVEESPLAQAVPPVCPQAVLERVSRMAAEQPDSDK", "length": 422, "header": "tr|A0A8V1A9L3-1|A0A8V1A9L3_CHICK Isoform 1 of Prune exopolyphosphatase 1 OS=Gallus gallus OX=9031 GN=PRUNE1 PE=1 SV=1 CANONICAL=A0A8V1A9L3-1" }, "locus": { "chromosome": "25", "start_pos": 2606613, "end_pos": 2603580, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069215.1", "url": "https://www.ensembl.org/id/ENSGALT00010069215.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042657.1", "url": "https://www.ensembl.org/id/ENSGALP00010042657.1" } ] } }, { "isoform_ac": "A0A8V1AL67-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9L3/entry#A0A8V1AL67-1", "sequence": { "sequence": "MGNEACDLDSTVSALALAYFLAKTSVPPKAAFIPVLNIPRADFALRTETTFLLREHSIPDSSLIFRDEIDLAGLHRAGLLSLTLVDHHVLPSTDAALEEAVVDVLDHRPLEREWAPSCQLTVELVGSCATLVTERIAQGPPGVLDRTTAALLHGTILLDSVNLSPAAGKVTPRDVLCVSLLESRFPELPPHDSIYGALQAAKFDVSGLTTEQMLRKDLKTVSGDEQVLAISGVYMDIELFLRRPGLLQDLETFCQTRGYSVLVAMTVSFNDCYEPTRQLAVYSQHEALRSTVCRALEEATTPALHLQALPSPWPCISAYAQGNTLASRKKVLPILRAALGGGPGTAAGPEEEAAPPPTPMNSLVEESPLAQAVPPVCPQAVLERVSRMAAEQPDSDK", "length": 397, "header": "tr|A0A8V1AL67-1|A0A8V1A9L3_CHICK Computationally mapped isoform of Prune exopolyphosphatase 1 OS=Gallus gallus OX=9031 GN=PRUNE1 PE=1 SV=1 CANONICAL=A0A8V1A9L3-1" }, "locus": { "chromosome": "25", "start_pos": 2606613, "end_pos": 2604784, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069216.1", "url": "https://www.ensembl.org/id/ENSGALT00010069216.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042658.1", "url": "https://www.ensembl.org/id/ENSGALP00010042658.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 383, "start_aa": "Thr", "end_pos": 383, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr383", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:427053", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427053", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1SDE2-1", "protein_name": "Exopolyphosphatase PRUNE1", "gene_name": "PRUNE1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEDYLQGCRAALQESRPLHVVLGNEACDLDSMVSALALAFYLAKTTEAEEVFVPVLNIKRSELPLRGDNVFFLQKIHIPESLLIFRDEIDLHALHQAGQLTLILVDHHVLPKTDAALEEAVAEVLDHRPIDQKHCPPCHVSVELVGSCATLVTERILQGAPEILDLQIAALLHGTIILDCVNMDLKIGKATPKDNKYVEKLEALFPDLPNRNDIFDSLQKAKFDVSGLTTEQMLRKDQKTISRQGIKVAISAIYMDLEAFLQRSGLIADLHAFCQAHSYDALVAMTIFFNTHNEPVRQLAVFCPHTALRVMICGVLESSHSPSLKLVPVPSTHPNLQAYLQGNTQVSRKKLLPLLQEALSAYFDSMKSPSGQPETAGVSREQVDKELDRAGNSLISGLSQDEEEPPLPPTPMNSLVDECPLDQGLPKFSAEVIFEKCSQISLSESTTASLSKK", "length": 453 }, "evidence": [ { "id": "A0A8V1A9L3", "url": "https://omabrowser.org/oma/group/A0A8V1A9L3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3H2Y2-1", "protein_name": "Exopolyphosphatase PRUNE1", "gene_name": "Prune1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEDYLQDCRAALQESRPLHVVLGNEACDLDSMVSALALAFYLTKTSESGEIFIPVLNINRSELPLRGDNVFFLQKVRIPEPVLIFRDEIDLHALHQAGQLTLTLVDHHVLPKSDAALEEAVAEVLDHRPIEQKYCPPCHVSVEHVGSCATLVAERILQGAPEILDRQTAFLLYGTIILDCVNMDAKVGKATLKDSKYVEKLEALFPDLPQREDIFDSLQKAKFDVSGLTTEQMLRKDQKTVCRQDTKVAISAVYMDLEAFLQRLDLLEDLSAFCHEHSYDALVAMTIFFNTHNEPVRQLAVFCPHSALRMTICGVLEQSTSPPLKLTPIPSISPDLQAYLQGNTQVSRKKLLPVLQEALSAYFDSTKMPSGQLGVVGMSREQGDKELDRAGSSIFGLSQDEEDPPLPPTPMNSLVDECPLDQGLPKLSAEAVFEKCSQISLSQSTRACPSNK", "length": 452 }, "evidence": [ { "id": "A0A8V1A9L3", "url": "https://omabrowser.org/oma/group/A0A8V1A9L3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P38698-1", "protein_name": "Polyphosphatase", "gene_name": "PPX1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSPLRKTVPEFLAHLKSLPISKIASNDVLTICVGNESADMDSIASAITYSYCQYIYNEGTYSEEKKKGSFIVPIIDIPREDLSLRRDVMYVLEKLKIKEEELFFIEDLKSLKQNVSQGTELNSYLVDNNDTPKNLKNYIDNVVGIIDHHFDLQKHLDAEPRIVKVSGSCSSLVFNYWYEKLQGDREVVMNIAPLLMGAILIDTSNMRRKVEESDKLAIERCQAVLSGAVNEVSAQGLEDSSEFYKEIKSRKNDIKGFSVSDILKKDYKQFNFQGKGHKGLEIGLSSIVKRMSWLFNEHGGEADFVNQCRRFQAERGLDVLVLLTSWRKAGDSHRELVILGDSNVVRELIERVSDKLQLQLFGGNLDGGVAMFKQLNVEATRKQVVPYLEEAYSNLEE", "length": 397 }, "evidence": [ { "id": "A0A8V1A9L3", "url": "https://omabrowser.org/oma/group/A0A8V1A9L3/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q5E9Y6-1", "protein_name": "Exopolyphosphatase PRUNE1", "gene_name": "PRUNE1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MENYLQGCRAALQESRPIHVVLGNEACDLDSMVSALALAFYLAKTTEAEEVFVPVLNIKRSELPLRGDNVFFLQKIHIPESVLIFRDEIDLHALHQAGQLTLILVDHHVLPKSDAALEEAVAEVLDHRPIDQRHCPPCHVSVELVGSCATLVAERILQGAPEILDRQTAALLHGTILLDCVNMDLKIGKATLKDSHYVEKLEALFPDLPSRNDIFDSLQKAKFDVSGLTTEQMLRKDQKTISRQGTKVAISAIYMDMEAFLQRSGLLADLRAFCQAHSYDALVAMTIFFNTYNEPVRQLAVFCPHAALRMTICGILEHSHSPPLKLTPVPSSHPDLQAYLQGNTQISRKKVLPLLQEALSAYFDSTNIPLGQPETEGVSREQVDKELDRAGNSLLSGLSQDEEEPPLPPTPMNSLVDECPLDQGLPKFSAEVIFEKCSQISLSEPTTASLSKK", "length": 453 }, "evidence": [ { "id": "A0A8V1A9L3", "url": "https://omabrowser.org/oma/group/A0A8V1A9L3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q6AYG3-1", "protein_name": "Exopolyphosphatase PRUNE1", "gene_name": "Prune1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEDYLQDCRAALQESRPLHVVLGNEACDLDSMVSALALAFYLTKTSEAEDIFIPVLNIKRSELPLRGDNVFFLQEVKIAESALIFRDEIDLLALHQAGQLTLILVDHHMLPKSDAALEEAVAEVLDHRPIEQKYCPPCHVSVELVGSCATLVAERILQGAPETLDRQTAALLHGTIILDCVNMDAKIGKATLKDNEYVEKLEALFPDLPKRKDIFDSLQKAKFDVSGLTTEQMLRKDQKTIYRQGTKVAVSAVYMDLEAFLQRSGLLSDLSAFCQDHSYDALVAMAIFFNTHNEPVRQLAIFCPHEALRMTICGVLEQSTSPALKLTPIPSISAHLQAYLQGNTQVSRKKLLPVLQEALSAYLDSMRTPAGQLEAALGMSREQADKELDKASNSLIAGLSQDDEDPPLPPTPMNSLVDECPLDQGLPKLSAEAVFEKCSQISLSQSTRACPSNK", "length": 454 }, "evidence": [ { "id": "A0A8V1A9L3", "url": "https://omabrowser.org/oma/group/A0A8V1A9L3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q86TP1-1", "protein_name": "Exopolyphosphatase PRUNE1", "gene_name": "PRUNE1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEDYLQGCRAALQESRPLHVVLGNEACDLDSTVSALALAFYLAKTTEAEEVFVPVLNIKRSELPLRGDIVFFLQKVHIPESILIFRDEIDLHALYQAGQLTLILVDHHILSKSDTALEEAVAEVLDHRPIEPKHCPPCHVSVELVGSCATLVTERILQGAPEILDRQTAALLHGTIILDCVNMDLKIGKATPKDSKYVEKLEALFPDLPKRNDIFDSLQKAKFDVSGLTTEQMLRKDQKTIYRQGVKVAISAIYMDLEAFLQRSNLLADLHAFCQAHSYDVLVAMTIFFNTHNEPVRQLAIFCPHVALQTTICEVLERSHSPPLKLTPASSTHPNLHAYLQGNTQVSRKKLLPLLQEALSAYFDSMKIPSGQPETADVSREQVDKELDRASNSLISGLSQDEEDPPLPPTPMNSLVDECPLDQGLPKLSAEAVFEKCSQISLSQSTTASLSKK", "length": 453 }, "evidence": [ { "id": "A0A8V1A9L3", "url": "https://omabrowser.org/oma/group/A0A8V1A9L3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BIW1-1", "protein_name": "Exopolyphosphatase PRUNE1", "gene_name": "Prune1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEDYLQDCRAALQDSRPLHVVLGNEACDLDSMVSALALAFYLTKTSEAEDIFIPVLNIKRSELPLRGDNVFFLQEVKIPEPALIFRDEIDLLALHQAGQLTLILVDHHILPKSDAALEEAVAEVLDHRPIEQKYCPPCHVSVELVGSCATLVTERILQGAPETLDRQTAALLHGTIILDCVNMDTNIGKATPKDSKYVEELEALFPDLPKRKDIFDSLQKAKFDVSGLTTEQMLRKDQKTVYRQGTKVAISAIYMDLKAFLQRTDLFTDLSSFCHDHSYDALVAMTIFFNTQNEPVRQLAIFCPHEALRMTICGILERSTSPPLKLTPIPSTSPNLQAYHQGNTQVSRKKLLPVLQEALSAYLDSAKMASGQSEVAVGMSREQVDKDLDKASNSLISGLSQDEEDPPLPPTPMNSLVDECPLDQGLPKFSAEAVFEKCSQISLSQSARACTSNK", "length": 454 }, "evidence": [ { "id": "A0A8V1A9L3", "url": "https://omabrowser.org/oma/group/A0A8V1A9L3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9L3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9L3" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9L3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9L3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "regulation of microtubule polymerization", "id": "GO:0031113", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031113", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9L3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9L3" } ], "pmid": "" }, { "name": "regulation of neurogenesis", "id": "GO:0050767", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050767", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9L3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9L3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "tubulin binding", "id": "GO:0015631", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015631", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9L3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9L3" } ], "pmid": "" }, { "name": "phosphatase activity", "id": "GO:0016791", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016791", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9L3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9L3" } ], "pmid": "" }, { "name": "exopolyphosphatase activity", "id": "GO:0004309", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004309", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9L3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9L3" } ], "pmid": "" }, { "name": "pyrophosphatase activity", "id": "GO:0016462", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016462", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9L3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9L3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 187, "end_pos": 189, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1A9L3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9L3" }, { "id": "SM01131", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM01131" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DHHA2", "eco_id": "ECO_0000259", "start_pos": 220, "end_pos": 364, "start_aa": "Tyr", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 383 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 187, "end_pos": 189 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A9L7-1", "uniprot_ac": "A0A8V1A9L7", "uniprot_id": "A0A8V1A9L7_CHICK", "mass": { "chemical_mass": 24964.0, "monoisotopic_mass": 24964.0 }, "refseq": {}, "gene_names": [ { "name": "C26H6ORF125", "type": "recommended", "evidence": [ { "id": "A0A8V1A9L7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9L7" } ] } ], "protein_names": [ { "name": "Mitochondrial nucleoid factor 1", "type": "recommended", "evidence": [ { "id": "A0A8V1A9L7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9L7/entry#names_and_taxonomy" } ] }, { "name": "Mitochondrial protein M19", "type": "synonym", "evidence": [ { "id": "A0A8V1A9L7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9L7/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9L7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9L7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "C26H6ORF125", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9L7", "locus": { "chromosome": "26", "start_pos": 4662617, "end_pos": 4655815, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027579", "url": "https://www.ensembl.org/id/ENSGALG00010027579" } ] } } ], "crossref": [ { "id": "A0A8V1A9L7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A9L7", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR037698", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037698", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A9L7", "url": "https://www.orthodb.org/?gene=A0A8V1A9L7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR34260", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR34260", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR34260:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR34260:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF20180", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20180", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1A9L7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9L7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A9L7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9L7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNTGQDSLGCEAASNQAPKQLSPPRCRPPGSGVCSPAARCLCRLQGAGAATSPTDGQRRAVQHPRRATLRCTARLDPRTALRMRGSAPPRHVTPMAATRYRRFLKLCEEWPVEETKRQRDLGVFIRQRVAQAFREGENTQIADPETCDQMYESLVRIHNNYYKNKYPRLKDTSFTGVTVQDCKMILATDILKQMEDMKKGTWRKLRERFYAKKSEEDSK", "length": 219, "header": "tr|A0A8V1A9L7-1|A0A8V1A9L7_CHICK Isoform 1 of Mitochondrial nucleoid factor 1 OS=Gallus gallus OX=9031 GN=C26H6ORF125 PE=1 SV=1 CANONICAL=A0A8V1A9L7-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A9L7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9L7/entry#A0A8V1A9L7-1", "sequence": { "sequence": "MNTGQDSLGCEAASNQAPKQLSPPRCRPPGSGVCSPAARCLCRLQGAGAATSPTDGQRRAVQHPRRATLRCTARLDPRTALRMRGSAPPRHVTPMAATRYRRFLKLCEEWPVEETKRQRDLGVFIRQRVAQAFREGENTQIADPETCDQMYESLVRIHNNYYKNKYPRLKDTSFTGVTVQDCKMILATDILKQMEDMKKGTWRKLRERFYAKKSEEDSK", "length": 219, "header": "tr|A0A8V1A9L7-1|A0A8V1A9L7_CHICK Isoform 1 of Mitochondrial nucleoid factor 1 OS=Gallus gallus OX=9031 GN=C26H6ORF125 PE=1 SV=1 CANONICAL=A0A8V1A9L7-1" }, "locus": { "chromosome": "26", "start_pos": 4660913, "end_pos": 4655962, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066805.1", "url": "https://www.ensembl.org/id/ENSGALT00010066805.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040884.1", "url": "https://www.ensembl.org/id/ENSGALP00010040884.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9L7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9L7" } ], "pmid": "" }, { "name": "mitochondrial nucleoid", "id": "GO:0042645", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042645", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9L7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9L7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "mitochondrial respiratory chain complex III assembly", "id": "GO:0034551", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034551", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9L7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9L7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A9L8-1", "uniprot_ac": "A0A8V1A9L8", "uniprot_id": "A0A8V1A9L8_CHICK", "mass": { "chemical_mass": 86747.0, "monoisotopic_mass": 86747.0 }, "refseq": {}, "gene_names": [ { "name": "USHBP1", "type": "recommended", "evidence": [ { "id": "A0A8V1A9L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9L8" } ] } ], "protein_names": [ { "name": "USH1 protein network component harmonin binding protein 1", "type": "synonym", "evidence": [ { "id": "A0A8V1A9L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9L8/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9L8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9L8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "USHBP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9L8", "locus": { "chromosome": "28", "start_pos": 3826199, "end_pos": 3830393, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028583", "url": "https://www.ensembl.org/id/ENSGALG00010028583" } ] } } ], "crossref": [ { "id": "A0A8V1A9L8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A9L8", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR019536", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019536", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040171", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040171", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A9L8", "url": "https://www.orthodb.org/?gene=A0A8V1A9L8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AEV5", "url": "https://www.orthodb.org/?gene=A0A8V1AEV5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23347", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23347", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23347:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23347:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10506", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10506", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1A9L8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9L8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A9L8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9L8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AEV5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEV5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AEV5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEV5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQIFLHSRTLSRVRAPSWLHGHPRAGEGPVWGRAGLRGGDGVPQSPPGVAVTRRRAAQRLSAGCSGAAEEEEISAGTRSGQGQGRPRGAPPAAGSAHCRIRSLWGRAVGPGAGRRRAMEEASGASPRARGAAGPQSSIVVPISAKLHPQLHRHPPAPSDPQGQAGQSPRAPLRLAGERLDEDEDRDEDEDEDEDEDAAAAGDEEHITTLLACTDPHSTRPLPHRDQEEHSGCTGSPHPHGQQPRGLDGAGTEAPHPDLFAALQHAVSSLERAVISRHRCTPAPPAEWAQSLEELQRVAGPCQGLGRGEGLLEEAERNAALRAALGDRDEELSRTTDALRALQGERERLQGKVWELQEALARLEGTGGAGGDTTGLSGAPGPGDPQDLSGCILSCDDAQPHGAQPHSPLSPPPSEGASRELEQRMQQLQGHMERLKEVNQQLSAALRDCKSDSERLSMVLGQHESRSSALHLALHCSERCVDAYAALLERMWAKLGRDGHGPSAGATGEQSTEHSCGSSPTQRLQLPDQAEPKRQEGSRVTSCPGLHSTHGSEEGALREAIRQLRAEQAAVQMSLHHVPTPSRAPSRRAEDACARAERALRDARALLPGWRRPERAELLREVAELKEAMAELRTRLQLAEREKRGLEVLAAAQGPREAALRLVLQHMEREQGAHSPPSGSSSSEEDAPMGAAAPQRPADPERTAQELQCALARMEQLHARAQALVLSLEQSSAVSRAQHEHCIAVTRESFHAHSALALAYRSARRKQAAQLQHLEARAGAVQQQQAQRMQALARRLQALEQHAAGGETCI", "length": 809, "header": "tr|A0A8V1A9L8-1|A0A8V1A9L8_CHICK Isoform 1 of USH1 protein network component harmonin binding protein 1 OS=Gallus gallus OX=9031 GN=USHBP1 PE=4 SV=1 CANONICAL=A0A8V1A9L8-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A9L8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9L8/entry#A0A8V1A9L8-1", "sequence": { "sequence": "MQIFLHSRTLSRVRAPSWLHGHPRAGEGPVWGRAGLRGGDGVPQSPPGVAVTRRRAAQRLSAGCSGAAEEEEISAGTRSGQGQGRPRGAPPAAGSAHCRIRSLWGRAVGPGAGRRRAMEEASGASPRARGAAGPQSSIVVPISAKLHPQLHRHPPAPSDPQGQAGQSPRAPLRLAGERLDEDEDRDEDEDEDEDEDAAAAGDEEHITTLLACTDPHSTRPLPHRDQEEHSGCTGSPHPHGQQPRGLDGAGTEAPHPDLFAALQHAVSSLERAVISRHRCTPAPPAEWAQSLEELQRVAGPCQGLGRGEGLLEEAERNAALRAALGDRDEELSRTTDALRALQGERERLQGKVWELQEALARLEGTGGAGGDTTGLSGAPGPGDPQDLSGCILSCDDAQPHGAQPHSPLSPPPSEGASRELEQRMQQLQGHMERLKEVNQQLSAALRDCKSDSERLSMVLGQHESRSSALHLALHCSERCVDAYAALLERMWAKLGRDGHGPSAGATGEQSTEHSCGSSPTQRLQLPDQAEPKRQEGSRVTSCPGLHSTHGSEEGALREAIRQLRAEQAAVQMSLHHVPTPSRAPSRRAEDACARAERALRDARALLPGWRRPERAELLREVAELKEAMAELRTRLQLAEREKRGLEVLAAAQGPREAALRLVLQHMEREQGAHSPPSGSSSSEEDAPMGAAAPQRPADPERTAQELQCALARMEQLHARAQALVLSLEQSSAVSRAQHEHCIAVTRESFHAHSALALAYRSARRKQAAQLQHLEARAGAVQQQQAQRMQALARRLQALEQHAAGGETCI", "length": 809, "header": "tr|A0A8V1A9L8-1|A0A8V1A9L8_CHICK Isoform 1 of USH1 protein network component harmonin binding protein 1 OS=Gallus gallus OX=9031 GN=USHBP1 PE=4 SV=1 CANONICAL=A0A8V1A9L8-1" }, "locus": { "chromosome": "28", "start_pos": 3830194, "end_pos": 3826445, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069220.1", "url": "https://www.ensembl.org/id/ENSGALT00010069220.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042662.1", "url": "https://www.ensembl.org/id/ENSGALP00010042662.1" } ] } }, { "isoform_ac": "A0A8V1AEV5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9L8/entry#A0A8V1AEV5-1", "sequence": { "sequence": "MQIFLHSRTLSRVRAPSWLHGHPRAGEGPVWGRAGLRGGDGVPQSPPGVAVTRRRAAQRLSAGCSGAAEEEEISAGTRSGQGQGRPRGAPPAAGSAHCRIRSLWGRAVGPGAGRRRAMEEGQAGQSPRAPLRLAGERLDEDEDRDEDEDEDEDEDAAAAGDEEHITTLLACTDPHSTRPLPHRDQEEHSGCTGSPHPHGQQPRGLDGAGTEAPHPDLFAALQHAVSSLERAVISRHRCTPAPPAEWAQSLEELQRVAGPCQGLGRGEGLLEEAERNAALRAALGDRDEELSRTTDALRALQGERERLQGKVWELQEALARLEGTGGAGGDTTGLSGAPGPGDPQDLSGCILSCDDAQPHGAQPHSPLSPPPSEGASRELEQRMQQLQGHMERLKEVNQQLSAALRDCKSDSERLSMVLGQHESRSSALHLALHCSERCVDAYAALLERMWAKLGRDGHGPSAGATGEQSTEHSCGSSPTQRLQLPDQAEPKRQEGSRVTSCPGLHSTHGSEEGALREAIRQLRAEQAAVQMSLHHVPTPSRAPSRRAEDACARAERALRDARALLPGWRRPERAELLREVAELKEAMAELRTRLQLAEREKRGLEVLAAAQGPREAALRLVLQHMEREQGAHSPPSGSSSSEEDAPMGAAAPQRPADPERTAQELQCALARMEQLHARAQALVLSLEQSSAVSRAQHEHCIAVTRESFHAHRWAEGA", "length": 717, "header": "tr|A0A8V1AEV5-1|A0A8V1AEV5_CHICK Computationally mapped isoform of USH1 protein network component harmonin binding protein 1 OS=Gallus gallus OX=9031 GN=USHBP1 PE=4 SV=1 CANONICAL=A0A8V1A9L8-1" }, "locus": { "chromosome": "28", "start_pos": 3830194, "end_pos": 3826892, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069222.1", "url": "https://www.ensembl.org/id/ENSGALT00010069222.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042664.1", "url": "https://www.ensembl.org/id/ENSGALP00010042664.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 52, "start_aa": "Thr", "end_pos": 52, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr52", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1A9L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9L8" }, { "id": "PF10506", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10506" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Harmonin-binding protein USHBP1 PDZ-binding", "eco_id": "ECO_0000259", "start_pos": 426, "end_pos": 487, "start_aa": "Gln", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 52 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { 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{ "database": "Ensembl Peptide", "id": "ENSGALP00010042672.1", "url": "https://www.ensembl.org/id/ENSGALP00010042672.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 160, "start_aa": "Thr", "end_pos": 160, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr160", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "resolution of meiotic recombination intermediates", "id": "GO:0000712", 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"https://www.uniprot.org/uniprotkb/A0A8V1A9M9" } ], "pmid": "" }, { "name": "manganese ion binding", "id": "GO:0030145", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030145", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9M9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9M9" } ], "pmid": "" }, { "name": "DNA endonuclease activity", "id": "GO:0004520", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004520", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9M9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9M9" } ], "pmid": "" }, { "name": "cobalt ion binding", "id": "GO:0050897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050897", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9M9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9M9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9M9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9M9" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9M9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9M9" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9M9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9M9" } ], "pmid": "" }, { "name": "midbody", "id": "GO:0030496", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030496", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9M9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9M9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 396, "end_pos": 398, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], 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"chemical_mass": 150373.0, "monoisotopic_mass": 150373.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Protein phosphatase 1 regulatory subunit 26", "type": "synonym", "evidence": [ { "id": "A0A8V1A9Q8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9Q8/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9Q8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9Q8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9Q8", "locus": {} } ], "crossref": [ { "id": "IPR026130", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026130", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031474", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031474", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A9Q8", "url": "https://www.orthodb.org/?gene=A0A8V1A9Q8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AH44", "url": "https://www.orthodb.org/?gene=A0A8V1AH44", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15724", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15724", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15724:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15724:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15740", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15740", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1A9Q8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9Q8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A9Q8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9Q8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AH44", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH44", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AH44-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH44-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFLMNASPLVALQTQWESFGPVRNCRYPVCFSESEGDVTRTSVHAKVQMIIRSLQSQESPLGMNNECECIMQKKQKGEKGTSNRVASSTTLLQKHPKYTKRSCPADSDDTEENVEFGTLLLDSDSDDSVDRGIEEAIQEYLKAKGKSDQSLQRNAECSENISRNKRLKREFSQNKMSSNLLPVKFKADMLSEEYFSDQLGIGKRLQPASPQSISSDDSFEQSIQAEIVQFLNEKKQQEISKCVIGQDKKDSHVRSVLKSNKQTTNKTNCGAVKRGCNALLLRHHPKLRKTSTQSKCLKSKIQEMPGDFNRVDQAYLEAASQPWLLQQNKESGTNYWEPRGALMDESIHGSDSSSDDGIEEAIQLYQLEKIRKEAGHTTDCVPLQREQFDTKGIADISASLTISSTKSASPETCKSPTSNKRKEINSKSTELESSSNDFNRLFKPLKKARHFVPPENKIAACELTLQASCRADTSAELMCAEAILDISKTIMPSQMGSDSKSLAADSFFSPQLLSSSHCESDSSLVDSDDSIEQEIQAFLALKAQSESLVTKPPGLSHSIQMPLPSDQNSLGGTLEPSLPKTLKLSLNRKKGLKREGRIAKQGASKASEQLGMGFFQPDNYSKVPVLQEGTLTSPEGLCGAQMLSSNETEQQQLSSELSESVGKCVALDSGNPFLQVQSGTRKLVKKTIRTQEGDGSDDESSSLDSDEDLDSAIKDLLRSKRKLKKKSKDQKSQCKKRVTCTETDSQLLDEVSDLQQSEWKCKNPMLLKSCLSKSRKAVKENAVRNHPDNINVSLSSERPEAIKNVEFDLQLKKGCKPEPISSQNNLQTAKNKKCTFTAASGTDDSSSVDSDDSIEQEIRKFLAEKAKDSASNSEMQKNEATLDLLTKQTANKGKVKQQSVENEIDFLLDRTKKTKGSQQTDELKSSQRMEGKSAMLPDSGKTASSAENVSFNTTGQSKAKQGMVGVKGAAGELPGKATGKKDVPNTEPMQKTLPPKTSKNEGRKRQKVSSAKPRSKRKNSFQLKISSKFIAGLKHARERKKSMLLNKKQKSEHLLNQSSSSGTEVASQDTNVLTREKGAPLPKGECSGENKIAIKESNSSQKLTVEVSGPRVAETCERPDAAPLYIKEAEGCKKAAAAGDQTDSHLNLPSQGQSVAAGQVDKVCRGTDKAESVQMGTEEGDSHKDSWADSNVGPPLLQHSMAVVEADKVSKETCQQSIQASGHGENNQQDNRQDPRVGCALQELNVTAVTADEASGEACAGNSEHMCMEEESITCQDSDRQSEIQVSSSSWEGKVPVLQNRETDCEPEPGQEVLEKDCAKCTDTPAGDSPDSFMKLKVSNNCLRTILCPRGLRSELTKQNSSRVGAAAGAEIWL", "length": 1374, "header": "tr|A0A8V1A9Q8-1|A0A8V1A9Q8_CHICK Isoform 1 of Protein phosphatase 1 regulatory subunit 26 OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1A9Q8-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A9Q8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9Q8/entry#A0A8V1A9Q8-1", "sequence": { "sequence": "MFLMNASPLVALQTQWESFGPVRNCRYPVCFSESEGDVTRTSVHAKVQMIIRSLQSQESPLGMNNECECIMQKKQKGEKGTSNRVASSTTLLQKHPKYTKRSCPADSDDTEENVEFGTLLLDSDSDDSVDRGIEEAIQEYLKAKGKSDQSLQRNAECSENISRNKRLKREFSQNKMSSNLLPVKFKADMLSEEYFSDQLGIGKRLQPASPQSISSDDSFEQSIQAEIVQFLNEKKQQEISKCVIGQDKKDSHVRSVLKSNKQTTNKTNCGAVKRGCNALLLRHHPKLRKTSTQSKCLKSKIQEMPGDFNRVDQAYLEAASQPWLLQQNKESGTNYWEPRGALMDESIHGSDSSSDDGIEEAIQLYQLEKIRKEAGHTTDCVPLQREQFDTKGIADISASLTISSTKSASPETCKSPTSNKRKEINSKSTELESSSNDFNRLFKPLKKARHFVPPENKIAACELTLQASCRADTSAELMCAEAILDISKTIMPSQMGSDSKSLAADSFFSPQLLSSSHCESDSSLVDSDDSIEQEIQAFLALKAQSESLVTKPPGLSHSIQMPLPSDQNSLGGTLEPSLPKTLKLSLNRKKGLKREGRIAKQGASKASEQLGMGFFQPDNYSKVPVLQEGTLTSPEGLCGAQMLSSNETEQQQLSSELSESVGKCVALDSGNPFLQVQSGTRKLVKKTIRTQEGDGSDDESSSLDSDEDLDSAIKDLLRSKRKLKKKSKDQKSQCKKRVTCTETDSQLLDEVSDLQQSEWKCKNPMLLKSCLSKSRKAVKENAVRNHPDNINVSLSSERPEAIKNVEFDLQLKKGCKPEPISSQNNLQTAKNKKCTFTAASGTDDSSSVDSDDSIEQEIRKFLAEKAKDSASNSEMQKNEATLDLLTKQTANKGKVKQQSVENEIDFLLDRTKKTKGSQQTDELKSSQRMEGKSAMLPDSGKTASSAENVSFNTTGQSKAKQGMVGVKGAAGELPGKATGKKDVPNTEPMQKTLPPKTSKNEGRKRQKVSSAKPRSKRKNSFQLKISSKFIAGLKHARERKKSMLLNKKQKSEHLLNQSSSSGTEVASQDTNVLTREKGAPLPKGECSGENKIAIKESNSSQKLTVEVSGPRVAETCERPDAAPLYIKEAEGCKKAAAAGDQTDSHLNLPSQGQSVAAGQVDKVCRGTDKAESVQMGTEEGDSHKDSWADSNVGPPLLQHSMAVVEADKVSKETCQQSIQASGHGENNQQDNRQDPRVGCALQELNVTAVTADEASGEACAGNSEHMCMEEESITCQDSDRQSEIQVSSSSWEGKVPVLQNRETDCEPEPGQEVLEKDCAKCTDTPAGDSPDSFMKLKVSNNCLRTILCPRGLRSELTKQNSSRVGAAAGAEIWL", "length": 1374, "header": "tr|A0A8V1A9Q8-1|A0A8V1A9Q8_CHICK Isoform 1 of Protein phosphatase 1 regulatory subunit 26 OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1A9Q8-1" }, "locus": { "chromosome": "17", "start_pos": 8321469, "end_pos": 8316893, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066913.1", "url": "https://www.ensembl.org/id/ENSGALT00010066913.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040931.1", "url": "https://www.ensembl.org/id/ENSGALP00010040931.1" } ] } }, { "isoform_ac": "A0A8V1AH44-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9Q8/entry#A0A8V1AH44-1", "sequence": { "sequence": "MFLMNASPLVALQTQWESFGPVRNCRYPVCFSESEGDVTRTSVHAKVQMIIRSLQSQESPLGMNNECECIMQKKQKGEKGTSNRVASSTTLLQKHPKYTKRSCPADSDDTEENVEFGTLLLDSDSDDSVDRGIEEAIQEYLKAKGKSDQSLQRNAECSENISRNKRLKREFSQNKMSSNLLPVKFKADMLSEEYFSDQLGIGKRLQPASPQSISSDDSFEQSIQAEIVQFLNEKKQQEISKCVIGQDKKDSHVRSVLKSNKQTTNKTNCGAVKRGCNALLLRHHPKLRKTSTQSKCLKSKIQEMPGDFNRVDQAYLEAASQPWLLQQNKESGTNYWEPRGALMDESIHGSDSSSDDGIEEAIQLYQLEKIRKEAGHTTDCVPLQREQFDTKGIADISASLTISSTKSASPETCKSPTSNKRKEINSKSTELESSSNDFNRLFKPLKKARHFVPPENKIAACELTLQASCRADTSAELMCAEAILDISKTIMPSQMGSDSKSLAADSFFSPQLLSSSHCESDSSLVDSDDSIEQEIQAFLALKAQSESLVTKPPGLSHSIQMPLPSDQNSLGGTLEPSLPKTLKLSLNRKKGLKREGRIAKQGASKASEQLGMGFFQPDNYSKVPVLQEGTLTSPEGLCGAQMLSSNETEQQQLSSELSESVGKCVALDSGNPFLQVQSGTRKLVKKTIRTQEGDGSDDESSSLDSDEDLDSAIKDLLRSKRKLKKKSKDQKSQCKKRVTCTETDSQLLDEVSDLQQSEWKCKNPMLLKSCLSKSRKAVKENAVRNHPDNINVSLSSERPEAIKNVEFDLQLKKGCKPEPISSQNNLQTAKNKKCTFTAASGTDDSSSVDSDDSIEQEIRKFLAEKAKDSASNSEMQKNEATLDLLTKQTANKGKVKQQSVENEIDFLLDRTKKTKGSQQTDELKSSQRMEGKSAMLPDSGKTASSAENVSFNTTGQSKAKQGMVGVKGAAGELPGKATGKKDVPNTEPMQKTLPPKTSKNEGRKRQKVSSAKPRSKRKNSFQLKISSKFIAGLKHARERKKSMLLNKKQKSEHLLNQSSSSGTEVASQDTNVLTREKGAPLPKGECSGENKIAIKESNSSQKLTVEVSGPRVAETCERPDAAPLYIKEAEGCKKAAAAGDQTDSHLNLPSQGQSVAAGQVDKVCRGTDKAESVQMGTEEGDSHKDSWADSNVGPPLLQHSMAVVEADKVSKETCQQSIQASGHGENNQQDNRQDPRVGCALQELNVTAVTADEASGEACAGNSEHMCMEEESITCQDSDRQSEIQVSSSSWEGKVPVLQNRETDCEPEPGQEVLEKDCAKCTDTPAGDSPDSFMKLKVSNK", "length": 1341, "header": "tr|A0A8V1AH44-1|A0A8V1A9Q8_CHICK Computationally mapped isoform of Protein phosphatase 1 regulatory subunit 26 OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1A9Q8-1" }, "locus": { "chromosome": "17", "start_pos": 8320915, "end_pos": 8316893, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066915.1", "url": "https://www.ensembl.org/id/ENSGALT00010066915.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040932.1", "url": "https://www.ensembl.org/id/ENSGALP00010040932.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein phosphatase inhibitor activity", "id": "GO:0004864", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004864", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9Q8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9Q8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1056, "end_pos": 1058, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1098, "end_pos": 1100, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1245, "end_pos": 1247, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1360, "end_pos": 1362, "annotation": "n_glycosylation_sequon" }, { "start_pos": 160, "end_pos": 162, "annotation": "n_glycosylation_sequon" }, { "start_pos": 265, "end_pos": 267, "annotation": "n_glycosylation_sequon" }, { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" }, { "start_pos": 619, "end_pos": 621, "annotation": "n_glycosylation_sequon" }, { "start_pos": 646, "end_pos": 648, "annotation": "n_glycosylation_sequon" }, { "start_pos": 791, "end_pos": 793, "annotation": "n_glycosylation_sequon" }, { "start_pos": 948, "end_pos": 950, "annotation": "n_glycosylation_sequon" }, { "start_pos": 952, "end_pos": 954, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1A9Q8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9Q8" }, { "id": "PF15740", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15740" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Protein phosphatase 1 regulatory subunit 26 N-terminal", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 869, "start_aa": "Met", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1056, "end_pos": 1058 }, { "start_pos": 1098, "end_pos": 1100 }, { "start_pos": 1245, "end_pos": 1247 }, { "start_pos": 1360, "end_pos": 1362 }, { "start_pos": 160, "end_pos": 162 }, { "start_pos": 265, "end_pos": 267 }, { "start_pos": 5, "end_pos": 7 }, { "start_pos": 619, "end_pos": 621 }, { "start_pos": 646, "end_pos": 648 }, { "start_pos": 791, "end_pos": 793 }, { "start_pos": 948, "end_pos": 950 }, { "start_pos": 952, "end_pos": 954 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A9R6-1", "uniprot_ac": "A0A8V1A9R6", "uniprot_id": "A0A8V1A9R6_CHICK", "mass": { "chemical_mass": 18303.0, "monoisotopic_mass": 18303.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Tachykinin 3", "type": "synonym", "evidence": [ { "id": "A0A8V1A9R6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9R6/entry#names_and_taxonomy" } ] } ], "function": [], 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"sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A9V8-1", "uniprot_ac": "A0A8V1A9V8", "uniprot_id": "A0A8V1A9V8_CHICK", "mass": { "chemical_mass": 30219.0, "monoisotopic_mass": 30219.0 }, "refseq": {}, "gene_names": [ { "name": "CRYGN", "type": "recommended", "evidence": [ { "id": "A0A8V1A9V8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9V8" } ] } ], "protein_names": [ { "name": "Crystallin gamma N", "type": "synonym", "evidence": [ { "id": "A0A8V1A9V8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9V8/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9V8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9V8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CRYGN", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9V8", "locus": { "chromosome": "2", "start_pos": 6266775, "end_pos": 6271874, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027125", "url": "https://www.ensembl.org/id/ENSGALG00010027125" } ] } } ], "crossref": [ { "id": "A0A8V1A9V8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A9V8", "database": "AlphaFoldDB", "categories": [] }, { "id": "428406", "url": "https://www.ncbi.nlm.nih.gov/gene/428406", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001064", "url": 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}, { "id": "PTHR11818:SF22", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11818:SF22", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00030", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00030", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1A9V8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9V8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A9V8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9V8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AES7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AES7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AES7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AES7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": 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CANONICAL=A0A8V1A9V8-1" }, "locus": { "chromosome": "2", "start_pos": 6271102, "end_pos": 6266865, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065757.1", "url": "https://www.ensembl.org/id/ENSGALT00010065757.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040023.1", "url": "https://www.ensembl.org/id/ENSGALP00010040023.1" } ] } }, { "isoform_ac": "A0A8V1AES7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9V8/entry#A0A8V1AES7-1", "sequence": { "sequence": "MRMGKTWLSFSSTGATAQRAAGAPFLKITFYEGKCFSGRKLEVCGTCSSFQQRGFPHRVNSIRVQSGAWVCFDHPELHGQQFVLEHGEYPHWQRWNGRGDRMGSCRPVGMHGQHYRIQLFEGSCFGGRSMELTEDCSCLRGRGWEQPHVNAVRVYGDGAWVLYEEPNYGGRMYVVERGEFGNFRAWQGFSANVQSVRRVINYF", "length": 203, "header": "tr|A0A8V1AES7-1|A0A8V1AES7_CHICK Computationally mapped isoform of Crystallin gamma N OS=Gallus gallus OX=9031 GN=CRYGN PE=3 SV=1 CANONICAL=A0A8V1A9V8-1" }, "locus": { "chromosome": "2", "start_pos": 6271630, "end_pos": 6266865, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065759.1", "url": "https://www.ensembl.org/id/ENSGALT00010065759.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040025.1", "url": "https://www.ensembl.org/id/ENSGALP00010040025.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0AAA9SAW0-1", "protein_name": "Gamma-crystallin N", "gene_name": "CRYGN", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MDGEADTLEITLYEGKHFTGRKLEVFGDCDNFQDHGFMNRVNSVRVESGAWVCFDHPDFRGQQFILEHGDYPDFYRWNGHNDHMGSCRPVRMHGEHFRLEIFEGCNFTGQCLEFKEDCPFLQSRGWTKNCVNAIKAYGDGAWVLYEEPNYRGRMYLVERGDFRSFSDWEAPSARVQSLRRVANF", "length": 184 }, "evidence": [ { "id": "A0A8V1A9V8", "url": "https://omabrowser.org/oma/group/A0A8V1A9V8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "D3ZEG1-1", "protein_name": "Gamma-crystallin N", "gene_name": "Crygn", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAQRSGKITLYEGKHFTGRKLEVFGDCDNFQDRGFMNRVNSIRVESGAWVCFDHPDFRGQQFILEHGDYPEFFRWNGHNDHMGSCRPVGMHGEHFRIDIFEGCNFTGQCLEFVEDCPFLQSRGWAKSCVNAIKVYGDGAWVLYEEPNYRGRMYVVERGDFRSFSDWEAHSARVQSLRRVLNFF", "length": 183 }, "evidence": [ { "id": "A0A8V1A9V8", "url": "https://omabrowser.org/oma/group/A0A8V1A9V8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8VHL5-1", "protein_name": "Gamma-crystallin N", "gene_name": "Crygn", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAQRSGKITLYEGKHFTGRKLEVFGDCDNFQDQGFMNRVNSIRVESGAWVCFDHPDFRGQQFILEHGDYPEFFRWNGHNDHMGSCRPVGMHGEHFRIDIFEGCNFTGQCLEFVEDCPFLQSRGWAKSCVNAIKVYGDGAWVLYEEPNYRGRMYVLERGDYRCFSDWGAHSARVQSLRRVLNFF", "length": 183 }, "evidence": [ { "id": "A0A8V1A9V8", "url": "https://omabrowser.org/oma/group/A0A8V1A9V8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8WXF5-1", "protein_name": "Gamma-crystallin N", "gene_name": "CRYGN", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAQRSGKITLYEGKHFTGQKLEVFGDCDNFQDRGFMNRVNSIHVESGAWVCFNHPDFRGQQFILEHGDYPDFFRWNSHSDHMGSCRPVGMHGEHFRLEIFEGCNFTGQCLEFLEDSPFLQSRGWVKNCVNTIKVYGDGAAWSPRSFGAEDFQLSSSLQSDQGPEEATTKPATTQPPFLTANL", "length": 182 }, "evidence": [ { "id": "A0A8V1A9V8", "url": "https://omabrowser.org/oma/group/A0A8V1A9V8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "visual perception", "id": "GO:0007601", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007601", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9V8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9V8" } ], "pmid": "" }, { "name": "lens development in camera-type eye", "id": "GO:0002088", "url": 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"field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A9X4-1", "uniprot_ac": "A0A8V1A9X4", "uniprot_id": "A0A8V1A9X4_CHICK", "mass": { "chemical_mass": 49128.0, "monoisotopic_mass": 49128.0 }, "refseq": { "ac": "XP_004949808", "name": "nuclear envelope integral membrane protein 1 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004949808" }, "gene_names": [ { "name": "NEMP1", "type": "recommended", "evidence": [ { "id": "A0A8V1A9X4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9X4" } ] }, { "name": "NEMP1", "type": "synonym", "evidence": [ { "id": "XP_004949808", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004949808" } ] } ], "protein_names": [ { "name": "Nuclear envelope integral membrane protein 1", "type": "synonym", "evidence": [ { "id": "A0A8V1A9X4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9X4/entry#names_and_taxonomy" } ] }, { "name": "nuclear envelope integral membrane protein 1 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_004949808", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004949808" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052565.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004949808.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004949808", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004949808" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9X4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9X4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NEMP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9X4", "locus": { "chromosome": "34", "start_pos": 1593928, "end_pos": 1598769, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010025337", "url": "https://www.ensembl.org/id/ENSGALG00010025337" } ] } } ], "crossref": [ { "id": "A0A8V1A9X4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A9X4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000031056", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000031056", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "769312", "url": "https://www.ncbi.nlm.nih.gov/gene/769312", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019358", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019358", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "MAGCMKM", "url": "https://omabrowser.org/oma/group/MAGCMKM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PS15", "url": "https://www.orthodb.org/?gene=A0A1D5PS15", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A9X4", "url": "https://www.orthodb.org/?gene=A0A8V1A9X4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13598", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13598", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13598:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13598:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10225", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10225", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004949808", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004949808", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PS15", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PS15", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PS15-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PS15-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A9X4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9X4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A9X4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9X4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTSDGPRSLIGCCLVLLCRRRALCCEDVKEKVTALQEGSACCCAASHHFCYTNVHSPCWRDIWTRMQIQVNSDRVIRVTQVGSEEELRELEESKVWNFLSSLLKEKLNSTNIDVDLYSNKTCLKVELLEDGTKYCIVLSRWFDPKLFLVFFLGLLLFFCGDMLSRSQLFFYSAGISIGLLASLLILIYVMSKAMPKKSPVYFLLVGGWSFSLYLLQLVFKNLREICKSYWQYLLGYLLLMGFVSFGVCYRYGPLENERSINLLSWALQLLGLALMYLGIQIRPIALALVVIAVCTKNMDYPLQWVYGVYKRVQSARLGPSPPRLLTEEEYRIQGEVETRKALEELRNYCRSPDFSAWTAVSRIQSPKRFAEFVGGASHLTASEVSFHEQEYGLGGVFLEEQLFEEDEEEDFLHEETARAARGPTTLLTAD", "length": 430, "header": "tr|A0A8V1A9X4-1|A0A8V1A9X4_CHICK Isoform 1 of Nuclear envelope integral membrane protein 1 OS=Gallus gallus OX=9031 GN=NEMP1 PE=3 SV=1 CANONICAL=A0A8V1A9X4-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PS15-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9X4/entry#A0A1D5PS15-1", "sequence": { "sequence": "MQIQVNSDRVIRVTQVGSEEELRELEESKVWNFLSSLLKEKLNSTNIDVDLYSNKTCLKVELLEDGTKYCIVLSRWFDPKLFLVFFLGLLLFFCGDMLSRSQLFFYSAGISIGLLASLLILIYVMSKAMPKKSPVYFLLVGGWSFSLYLLQLVFKNLREICKSYWQYLLGYLLLMGFVSFGVCYRYGPLENERSINLLSWALQLLGLALMYLGIQIRPIALALVVIAVCTKNMDYPLQWVYGVYKRVQSARLGPSPPRLLTEEEYRIQGEVETRKALEELRNYCRSPDFSAWTAVSRIQSPKRFAEFVGGASHLTASEVSFHEQEYGLGGVFLEEQLFEEDEEEDFLHEETARAARGPTTLLTAD", "length": 365, "header": "tr|A0A1D5PS15-1|A0A1D5PS15_CHICK Computationally mapped isoform of Nuclear envelope integral membrane protein 1 OS=Gallus gallus OX=9031 GN=NEMP1 PE=3 SV=2 CANONICAL=A0A8V1A9X4-1" }, "locus": { "chromosome": "34", "start_pos": 1597903, "end_pos": 1595183, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010061859.1", "url": "https://www.ensembl.org/id/ENSGALT00010061859.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038188.1", "url": "https://www.ensembl.org/id/ENSGALP00010038188.1" } ] } }, { "isoform_ac": "A0A8V1A9X4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9X4/entry#A0A8V1A9X4-1", "sequence": { "sequence": "MTSDGPRSLIGCCLVLLCRRRALCCEDVKEKVTALQEGSACCCAASHHFCYTNVHSPCWRDIWTRMQIQVNSDRVIRVTQVGSEEELRELEESKVWNFLSSLLKEKLNSTNIDVDLYSNKTCLKVELLEDGTKYCIVLSRWFDPKLFLVFFLGLLLFFCGDMLSRSQLFFYSAGISIGLLASLLILIYVMSKAMPKKSPVYFLLVGGWSFSLYLLQLVFKNLREICKSYWQYLLGYLLLMGFVSFGVCYRYGPLENERSINLLSWALQLLGLALMYLGIQIRPIALALVVIAVCTKNMDYPLQWVYGVYKRVQSARLGPSPPRLLTEEEYRIQGEVETRKALEELRNYCRSPDFSAWTAVSRIQSPKRFAEFVGGASHLTASEVSFHEQEYGLGGVFLEEQLFEEDEEEDFLHEETARAARGPTTLLTAD", "length": 430, "header": "tr|A0A8V1A9X4-1|A0A8V1A9X4_CHICK Isoform 1 of Nuclear envelope integral membrane protein 1 OS=Gallus gallus OX=9031 GN=NEMP1 PE=3 SV=1 CANONICAL=A0A8V1A9X4-1" }, "locus": { "chromosome": "34", "start_pos": 1598570, "end_pos": 1595183, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010061862.1", "url": "https://www.ensembl.org/id/ENSGALT00010061862.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038189.1", "url": "https://www.ensembl.org/id/ENSGALP00010038189.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A7MBC7-1", "protein_name": "Nuclear envelope integral membrane protein 1", "gene_name": "NEMP1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAGGMKVAVLPAVGAGPWSWGAGGCGAVRLLLVLFGCFVCGSAGIDLNVVTLRESEILFMNTSRQSCYKNVLIPKWHDIWTRIQIRVNSSKLVRVTQVENEDKLKELEQFSIWNFFSSFLKEKLNDTYINVGLYSTKTCLKVEILEEDTKYSVIVTRRFDPKLFLIFLLGLTLFFCGDLLSRSQIFYYSTGMSVGIVASLLIIIFIVSKFMPKKSPIYIILVGGWSFSLYLIQLVFKNLQEIWRCYWQYLLSYVLAVGFMSFAVCYKYGPLENERSINLLTWTLQLLGLCFMYSSIQIPHIALAIVVIALCTKNLDYPIHWLYITYRKMCKATEKTVPPRLLTEEEYRLQGEVETRKALEQLREYCNSPDCSAWKTVSRIQSPKRFADFVEGSFHLTPNEVSVHEQEYGLGSIIAQDELSEETSSEEEDSDSRYPLVVQQNSFLT", "length": 445 }, "evidence": [ { "id": "A0A8V1A9X4", "url": "https://omabrowser.org/oma/group/A0A8V1A9X4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "E7FE40-1", "protein_name": "Nuclear envelope integral membrane protein 1", "gene_name": "nemp1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAGFMKYKSVSTTIETVRLKLILTAVLFLFPFSQTSGASRPIIEIKDGQEIKVQAAQHFCYNNTIIPGWRETWTRIQVRVWSTTKLKVTVVNDEQDLKELEHFSIWKLVQYFVREQTNETTISVSLFNNKTCFRVDPSESRTLYTVQPSRHFDIYLFLVFLAGVLLFFYADVLSRSQVFHYSAGMSTGMIASLLILIFIVYRFLPKKSPFYMLVVGGWSFSLYIIQLVFRNLQVILTDHWHLAIGYVFVVGFISFAVCYRYGPLVEERSINILSWALQIFGLLLVYAGIQVQQVAFAIMIAAFCSKNLEYPFNTAFMLYHKLKPKKLEPRRLLTEEEFQRQSEVETQKALEELRKYCGSPDFNTWKTVSRLQSPKRFADFIEGSPHLLSNEVSVHMQEYGLGGSFFEDELFSTDEEDKEEEEDGWETEDDIKPEVTSPRMNNTRGK", "length": 446 }, "evidence": [ { "id": "A0A8V1A9X4", "url": "https://omabrowser.org/oma/group/A0A8V1A9X4/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1SL61-1", "protein_name": "Nuclear envelope integral membrane protein 1", "gene_name": "NEMP1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAGGMKVAVLPAVGSGPWSWRSGGCGAVWLLLVLSGCLVCGSAGIDLKVVMLQESKVYCMNTSQQSCYKNVLIPKWHDVWTRIQIRVNSSKLVRVTQVENEEKLKELEQFSIWNFFSSFLKEKLNDTYVNVGLYSTKTCLKVEIIEEDTKYSVTVTRRFDPKLFLIFLLGLMLFFCGDLLSRSQIFYYSTGMSVGIVASLLIIIFILSKFMPKKSPIYIILVGGWSFSLYLIQLVFKNLQEIWRCYWQYLLSYVLAVGFMSFAVCYKYGPLENERSINLLTWTLQLMGLCFMYSSIQIPQISLAIIITALCTKNLEYPIHWLYITYRKMCKAAEKTVPPRLLTEEEYRIQGEVETRKALEKLREYCNSPDCAAWKTVSRIQSPKRFADFVEGSFHLTPNEVSVHEQEYGLGSIIAQDELYEETSSEEGDTDSRYPAITQQNNFLT", "length": 445 }, "evidence": [ { "id": "A0A8V1A9X4", "url": "https://omabrowser.org/oma/group/A0A8V1A9X4/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "M0R7R7-1", "protein_name": "Nuclear envelope integral membrane protein 1", "gene_name": "Nemp1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGGIKVAVWSAVGPGPGCCGAGGGGAAWLLLVVAGCVVGCSAGIDVNVVMLQESQVDMNSSQQFCYKNVLIPKWHDIWTRIQVRVNSSKLVRVTQVDSEERLKELEQFSVWNSLSSFLKEKLNDTYVNVGLYSTKTCLKVEIIEKDTKYSVIVTRRFDPKLFLVFLLGLTLFFCGDLLSRSQIFYYSTGMSVGIVASLLIVIFMISKLMPKRSPIYVILVGGWSFSLYLIQLVFKNLQEIWRCYWHYLLSYILTVGFMSFAVCYKYGPLENERSINLLTWTLQLLGLGFMYSGIQIPHVAFALIVIALCTKNLEYPIYWLYSTYRRMCKASEKPVPPRLLTEEEYRIQGEVETQKALQELREFCNSPECSAWKTISRIQSPKRFADFVEGSFHLTPNEVSVHEQEYGLGSILAQDEELSSEEEGSEDLPLTQNSFLT", "length": 438 }, "evidence": [ { "id": "A0A8V1A9X4", "url": "https://omabrowser.org/oma/group/A0A8V1A9X4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O14524-1", "protein_name": "Nuclear envelope integral membrane protein 1", "gene_name": "NEMP1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAGGMKVAVSPAVGPGPWGSGVGGGGTVRLLLILSGCLVYGTAETDVNVVMLQESQVCEKRASQQFCYTNVLIPKWHDIWTRIQIRVNSSRLVRVTQVENEEKLKELEQFSIWNFFSSFLKEKLNDTYVNVGLYSTKTCLKVEIIEKDTKYSVIVIRRFDPKLFLVFLLGLMLFFCGDLLSRSQIFYYSTGMTVGIVASLLIIIFILSKFMPKKSPIYVILVGGWSFSLYLIQLVFKNLQEIWRCYWQYLLSYVLTVGFMSFAVCYKYGPLENERSINLLTWTLQLMGLCFMYSGIQIPHIALAIIIIALCTKNLEHPIQWLYITCRKVCKGAEKPVPPRLLTEEEYRIQGEVETRKALEELREFCNSPDCSAWKTVSRIQSPKRFADFVEGSSHLTPNEVSVHEQEYGLGSIIAQDEIYEEASSEEEDSYSRCPAITQNNFLT", "length": 444 }, "evidence": [ { "id": "A0A8V1A9X4", "url": "https://omabrowser.org/oma/group/A0A8V1A9X4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6ZQE4-1", "protein_name": "Nuclear envelope integral membrane protein 1", "gene_name": "Nemp1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAGGIKVSVWSAVGPGPRCWGAGGGGGATWLLLVVAGCVVCGSADVNVVMLQESQVDMNSSQQFCYKNVLIPKWHDIWTRIQVRVNSSKLVRVTQVDNEEKLKELEQFSIWNFFSSFLKEKLNDTYVNVGLYSTKTCLKVEMIEKDTTYSVTVTRRFDPKLFLVFLLGLTLFFCGDLLSRSQIFYYSTGMSVGIVASLLIVIFMISKFMPKRSPIYVILVGGWSFSLYLIQLVFKNLQEIWRSYWHYLLSYILTVGFMSFAVCYKYGPLENERSINLLTWTLQLLGLGLMYSSIQIPHVAFALIVIALCTKNLEYPIHWLCSTYRRMCKASGKPVPPRLLTEEEYRIQGEVETQKALQELREFCNSPECSAWKTISRIQSPKRFADFVEGSFHLTPNEVSVHEQEYGLGSIFTQDEELSSEEEGSEYPTFTQNNFLT", "length": 437 }, "evidence": [ { "id": "A0A8V1A9X4", "url": "https://omabrowser.org/oma/group/A0A8V1A9X4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nuclear envelope", "id": "GO:0005635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005635", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9X4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9X4" } ], "pmid": "" }, { "name": "nuclear inner membrane", "id": "GO:0005637", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005637", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9X4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9X4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "nuclear membrane organization", "id": "GO:0071763", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071763", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9X4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9X4" } ], "pmid": "" }, { "name": "erythrocyte enucleation", "id": "GO:0043131", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043131", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9X4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9X4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 108, "end_pos": 110, "annotation": "n_glycosylation_sequon" }, { "start_pos": 119, "end_pos": 121, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], 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106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052556.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. 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"table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1A9Y6-1", "uniprot_ac": "A0A8V1A9Y6", "uniprot_id": "A0A8V1A9Y6_CHICK", "mass": { "chemical_mass": 269689.0, "monoisotopic_mass": 269689.0 }, "refseq": { "ac": "NP_001292609", "name": "centriolin", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292609" }, "gene_names": [ { "name": "CNTRL", "type": "recommended", "evidence": [ { "id": "A0A8V1A9Y6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9Y6" } ] }, { "name": "CEP110", "type": "synonym", "evidence": [ { "id": "NP_001292609", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292609" } ] }, { "name": "CNTRL", "type": "synonym", "evidence": [ { "id": "NP_001292609", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292609" } ] } ], "protein_names": [ { "name": "Centriolin", "type": "synonym", "evidence": [ { "id": "A0A8V1A9Y6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9Y6/entry#names_and_taxonomy" } ] }, { "name": "centriolin", "type": "synonym", "evidence": [ { "id": "NP_001292609", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292609" } ] }, { "name": "centrosomal protein 110kDa", "type": "synonym", "evidence": [ { "id": "NP_001292609", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292609" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000308.1. On Dec 3, 2021 this sequence version replaced NP_001292609.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001292609", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292609" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9Y6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9Y6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CNTRL", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9Y6", "locus": { "chromosome": "17", "start_pos": 8984955, "end_pos": 8952807, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027672", "url": "https://www.ensembl.org/id/ENSGALG00010027672" } ] } } ], "crossref": [ { "id": "417121", "url": "https://www.ncbi.nlm.nih.gov/gene/417121", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003591", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003591", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050576", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050576", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:417121", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417121", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "XYIENLE", "url": "https://omabrowser.org/oma/group/XYIENLE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A9Y6", "url": "https://www.orthodb.org/?gene=A0A8V1A9Y6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ACP7", "url": "https://www.orthodb.org/?gene=A0A8V1ACP7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45973", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45973", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45973:SF36", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45973:SF36", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14580", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14580", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001292609", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292609", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1A9Y6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9Y6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A9Y6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9Y6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ACP7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACP7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ACP7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACP7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKKSYKKKELCGKTQMSAFRTPTPMSSVGSSTRSPSPLSQQTSPPARKSTAWQNQQRDTTANVEAALESKFHEEENGVSPGVRYITEPLIKSLSKQENLAYISSLNLSSPKDGDKKFKYIENLEKCSKLERLNLSNNQIEKIEKLDKLLKLRELNLSYNKISKIEGMEHLHNLQKMNLAGNEIEHIPVWVGKKLRSLRILNLKQNKVSSLHEIAKLKPLQDLTSLFLAGNPVASLPHYRLYIIFHLRALENLDGQPVTNHDRQEALKRFDLEEIEKLERELENAIKEMENLKLNQSKVLEQLHHQDEVNKSLKEKTLQQKQSCEDLQRDVDTKNELLKQKTMELTRACQKQYELEQELAFYKIDAKFEPLSYFPSEDVELEDVPGESPYIGKARYKRNMFIREGYIASKAQQVETGKMQPDENDFCKKSQLNPQFQTVDEQLESKEKKIHSAQRRLEELQNAIGKAEQQVLEVTGELQQLEGALAQKKVLQANREDLEQQLSKKIQTLHQLQEGALALEKQMEKQKREIGKKQKELEDLKSSLASVNSKEPRHAHMRAQKASKEQQIEVMNKQYKQLESRLDEMLSRIAKETEEIKDLEQQLTDGQIATNEALKRDLESIIIGLQEYLESVKHQAKQANDECKELQKDKESLLQRLADLEDERNSLKIVVMDAENMRKEIAMLEGALQEQREINESLREGQGDVSAYEAELEAQLRERDTEANQQKEELERLKQLSQMELSALQAELEKERQALENALTKAQLAEEKEQENYKLLSQFKQLQGDNNLLKQQLKDLQNQLSHAVGNLIHPEEVLARINELKQKLRTGAGEIKCQNSADVLGKSLASLQKEFNNILADTQREKEKAWERQRQLQEEMVSQKEKLEDIQEKYRQVKSENRQNKNKVHQLENEIQLLREKIKSMEEIQGLADQQLQEADEEKEAILAQLEDLEKRKKIEDARAQMQFADLDKELKELKRAIITADKLAAAELSIAKNQLQALHGTVLKINQERAEEFEEAEEFCVEAARATRDLARAEAEIELLQQLLKQKEEQLQHEMGKAGEKTALSSQKLEIDQLNDTVEQQKAEIDHLRWLLDDIGAGNKDEIDNLQEEIAALRSALSYQNDYITNIADPLKRRGYWYYMPPSQASTPASHSTKDSGVGLQYPGTSPPRRGCSQVRKEDLPRSRGCWVYSPVRNRLHKTNLDKAGRAKEDREGNEEAHAHKDPPFVPPPGTVIYTVLPDGAPLPEGTVAYGPPPAAANGGSIAPGSVIYGPPPVGAQVVYGLLPPNFTVPLIPFGDLHCNVPKHHDLESEVSRLEDTVQHLKSRKYRDKWSEAAEHKCKNEMEKIHQNIEDLLHEREELEREVAELQRTAQKRNKCKDFVEGYTENLMAELQLEKSLKHHEDVAEEIECIEKTLLKRRAELREADRLLAEAELELESTRGKTKDTIQKYNHAKQHLFRTETEAEELERRAQEMATKLVKADQQLRSLQADTRDLEQHKKEQEGILKEINKMVSARDSEFQSLNQKIEMLTESLQKLQGDIQAAEGNEEHHLQMLREVEDILQVKKTEQERLKNQVTAQQQELLFLEQQLSQRKEQLRVLQDCISQKKGDLKEALRDGETEAKEKQRQIREIKLLLEDLNAERRELDVQIDEKRAQLLFIKKDIGKEEENLQIILGQINKHKIELKHVLEMLEIENNELQGLKLQHNQKVNELEKTQVAVLEEKLKLENIQRLFHCQQGEVDWQEQLLQKDRQENEHLVSQMRTLQNNIESLNKEKQKLEEDCQSLEKKLSQTRRDLTATEDSIKTALSNVEKRELDIKNLQQEIDVLNKQKKSLHGDITVVQKDLQEKKNELEMLKGELSESRQQLQLAEQNLKDNTKHQEELLREQATLKEDILKCVRKCKDCQERQKKRENHLQQLQKEIEEKETILAKQEAILCNLKQNSEHEGKKLEENTAKLKEQKLLLEKELMDQREKLEQAVAKVRLTEENNRKLEKEASQFAALEETIRKSKHQVSEKELQLQQKNREIQSLQKELELSKSELNHLQGQLASERKRAEKRICSLKEAMKMQRTQFERELHEQKRENNCLQSDIAAAEQVAQNNHERTKRLIKELGQIQQDYMDLQNQVKTQEDLEKRQREIENTATLLKLEVEDDIKTGFKSSSPSSPELLEDLEAFSAVNKSLQCESDNLEEMFSFADADKRLFSSEKKLDFSQIFIMDEQWRGEALREKLQHHEDRLKAQLRHCMSKQVDVLIRGKQQTQGTLHSLKRQVDALDDLVSSTSSDSLFLAESSSSLLSLRDALSLTKTQAALTGHAHFPSSSAGVPAVAHTWHSCS", "length": 2334, "header": "tr|A0A8V1A9Y6-1|A0A8V1A9Y6_CHICK Isoform 1 of Centriolin OS=Gallus gallus OX=9031 GN=CNTRL PE=4 SV=1 CANONICAL=A0A8V1A9Y6-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A9Y6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9Y6/entry#A0A8V1A9Y6-1", "sequence": { "sequence": "MKKSYKKKELCGKTQMSAFRTPTPMSSVGSSTRSPSPLSQQTSPPARKSTAWQNQQRDTTANVEAALESKFHEEENGVSPGVRYITEPLIKSLSKQENLAYISSLNLSSPKDGDKKFKYIENLEKCSKLERLNLSNNQIEKIEKLDKLLKLRELNLSYNKISKIEGMEHLHNLQKMNLAGNEIEHIPVWVGKKLRSLRILNLKQNKVSSLHEIAKLKPLQDLTSLFLAGNPVASLPHYRLYIIFHLRALENLDGQPVTNHDRQEALKRFDLEEIEKLERELENAIKEMENLKLNQSKVLEQLHHQDEVNKSLKEKTLQQKQSCEDLQRDVDTKNELLKQKTMELTRACQKQYELEQELAFYKIDAKFEPLSYFPSEDVELEDVPGESPYIGKARYKRNMFIREGYIASKAQQVETGKMQPDENDFCKKSQLNPQFQTVDEQLESKEKKIHSAQRRLEELQNAIGKAEQQVLEVTGELQQLEGALAQKKVLQANREDLEQQLSKKIQTLHQLQEGALALEKQMEKQKREIGKKQKELEDLKSSLASVNSKEPRHAHMRAQKASKEQQIEVMNKQYKQLESRLDEMLSRIAKETEEIKDLEQQLTDGQIATNEALKRDLESIIIGLQEYLESVKHQAKQANDECKELQKDKESLLQRLADLEDERNSLKIVVMDAENMRKEIAMLEGALQEQREINESLREGQGDVSAYEAELEAQLRERDTEANQQKEELERLKQLSQMELSALQAELEKERQALENALTKAQLAEEKEQENYKLLSQFKQLQGDNNLLKQQLKDLQNQLSHAVGNLIHPEEVLARINELKQKLRTGAGEIKCQNSADVLGKSLASLQKEFNNILADTQREKEKAWERQRQLQEEMVSQKEKLEDIQEKYRQVKSENRQNKNKVHQLENEIQLLREKIKSMEEIQGLADQQLQEADEEKEAILAQLEDLEKRKKIEDARAQMQFADLDKELKELKRAIITADKLAAAELSIAKNQLQALHGTVLKINQERAEEFEEAEEFCVEAARATRDLARAEAEIELLQQLLKQKEEQLQHEMGKAGEKTALSSQKLEIDQLNDTVEQQKAEIDHLRWLLDDIGAGNKDEIDNLQEEIAALRSALSYQNDYITNIADPLKRRGYWYYMPPSQASTPASHSTKDSGVGLQYPGTSPPRRGCSQVRKEDLPRSRGCWVYSPVRNRLHKTNLDKAGRAKEDREGNEEAHAHKDPPFVPPPGTVIYTVLPDGAPLPEGTVAYGPPPAAANGGSIAPGSVIYGPPPVGAQVVYGLLPPNFTVPLIPFGDLHCNVPKHHDLESEVSRLEDTVQHLKSRKYRDKWSEAAEHKCKNEMEKIHQNIEDLLHEREELEREVAELQRTAQKRNKCKDFVEGYTENLMAELQLEKSLKHHEDVAEEIECIEKTLLKRRAELREADRLLAEAELELESTRGKTKDTIQKYNHAKQHLFRTETEAEELERRAQEMATKLVKADQQLRSLQADTRDLEQHKKEQEGILKEINKMVSARDSEFQSLNQKIEMLTESLQKLQGDIQAAEGNEEHHLQMLREVEDILQVKKTEQERLKNQVTAQQQELLFLEQQLSQRKEQLRVLQDCISQKKGDLKEALRDGETEAKEKQRQIREIKLLLEDLNAERRELDVQIDEKRAQLLFIKKDIGKEEENLQIILGQINKHKIELKHVLEMLEIENNELQGLKLQHNQKVNELEKTQVAVLEEKLKLENIQRLFHCQQGEVDWQEQLLQKDRQENEHLVSQMRTLQNNIESLNKEKQKLEEDCQSLEKKLSQTRRDLTATEDSIKTALSNVEKRELDIKNLQQEIDVLNKQKKSLHGDITVVQKDLQEKKNELEMLKGELSESRQQLQLAEQNLKDNTKHQEELLREQATLKEDILKCVRKCKDCQERQKKRENHLQQLQKEIEEKETILAKQEAILCNLKQNSEHEGKKLEENTAKLKEQKLLLEKELMDQREKLEQAVAKVRLTEENNRKLEKEASQFAALEETIRKSKHQVSEKELQLQQKNREIQSLQKELELSKSELNHLQGQLASERKRAEKRICSLKEAMKMQRTQFERELHEQKRENNCLQSDIAAAEQVAQNNHERTKRLIKELGQIQQDYMDLQNQVKTQEDLEKRQREIENTATLLKLEVEDDIKTGFKSSSPSSPELLEDLEAFSAVNKSLQCESDNLEEMFSFADADKRLFSSEKKLDFSQIFIMDEQWRGEALREKLQHHEDRLKAQLRHCMSKQVDVLIRGKQQTQGTLHSLKRQVDALDDLVSSTSSDSLFLAESSSSLLSLRDALSLTKTQAALTGHAHFPSSSAGVPAVAHTWHSCS", "length": 2334, "header": "tr|A0A8V1A9Y6-1|A0A8V1A9Y6_CHICK Isoform 1 of Centriolin OS=Gallus gallus OX=9031 GN=CNTRL PE=4 SV=1 CANONICAL=A0A8V1A9Y6-1" }, "locus": { "chromosome": "17", "start_pos": 8984021, "end_pos": 8954355, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067096.1", "url": "https://www.ensembl.org/id/ENSGALT00010067096.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041016.1", "url": "https://www.ensembl.org/id/ENSGALP00010041016.1" } ] } }, { "isoform_ac": "A0A8V1ACP7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9Y6/entry#A0A8V1ACP7-1", "sequence": { "sequence": "MGTRNSNKIEGMEHLHNLQKMNLAGNEIEHIPVWVGKKLRSLRILNLKQNKVSSLHEIAKLKPLQDLTSLFLAGNPVASLPHYRLYIIFHLRALENLDGQPVTNHDRQEALKRFDLEEIEKLERELENAIKEMENLKLNQSKVLEQLHHQDEVNKSLKEKTLQQKQSCEDLQRDVDTKNELLKQKTMELTRACQKQYELEQELAFYKIDAKFEPLSYFPSEDVELEDVPGESPYIGKARYKRNMFIREGYIASKAQQVETGKMQPDENDFCKKSQLNPQFQTVDEQLESKEKKIHSAQRRLEELQNAIGKAEQQVLEVTGELQQLEGALAQKKVLQANREDLEQQLSKKIQTLHQLQEGALALEKQMEKQKREIGKKQKELEDLKSSLASVNSKEPRHAHMRAQKASKEQQIEVMNKQYKQLESRLDEMLSRIAKETEEIKDLEQQLTDGQIATNEALKRDLESIIIGLQEYLESVKHQAKQANDECKELQKDKESLLQRLADLEDERNSLKIVVMDAENMRKEIAMLEGALQEQREINESLREGQGDVSAYEAELEAQLRERDTEANQQKEELERLKQLSQMELSALQAELEKERQALENALTKAQLAEEKEQENYKLLSQFKQLQGDNNLLKQQLKDLQNQLSHAVGNLIHPEEVLARINELKQKLRTGAGEIKCQNSADVLGKSLASLQKEFNNILADTQREKEKAWERQRQLQEEMVSQKEKLEDIQEKYRQVKSENRQNKNKVHQLENEIQLLREKIKSMEEIQGLADQQLQEADEEKEAILAQLEDLEKRKKIEDARAQMQFADLDKELKELKRAIITADKLAAAELSIAKNQLQALHGTVLKINQERAEEFEEAEEFCVEAARATRDLARAEAEIELLQQLLKQKEEQLQHEMGKAGEKTALSSQKLEIDQLNDTVEQQKAEIDHLRWLLDDIGAGNKDEIDNLQEEIAALRSALSYQNDYITNIADPLKRRGYWYYMPPSQASTPASHSTKDSGVGLQYPGTSPPRRGCSQVRKEDLPRSRGCWVYSPVRNRLHKTNLDKAGRAKEDREGNEEAHAHKDPPFVPPPGTVIYTVLPDGAPLPEGTVAYGPPPAAANGGSIAPGSVIYGPPPVGAQVVYGLLPPNFTVPLIPFGDLHCNVPKHHDLESEVSRLEDTVQHLKSRKYRDKWSEAAEHKCKNEMEKIHQNIEDLLHEREELEREVAELQRTAQKRNKCKDFVEGYTENLMAELQLEKSLKHHEDVAEEIECIEKTLLKRRAELREADRLLAEAELELESTRGKTKDTIQKYNHAKQHLFRTETEAEELERRAQEMATKLVKADQQLRSLQADTRDLEQHKKEQEGILKEINKMVSARDSEFQSLNQKIEMLTESLQKLQGDIQAAEGNEEHHLQMLREVEDILQVKKTEQERLKNQVTAQQQELLFLEQQLSQRKEQLRVLQDCISQKKGDLKEALRDGETEAKEKQRQIREIKLLLEDLNAERRELDVQIDEKRAQLLFIKKDIGKEEENLQIILGQINKHKIELKHVLEMLEIENNELQGLKLQHNQKVNELEKTQVAVLEEKLKLENIQRLFHCQQGEVDWQEQLLQKDRQENEHLVSQMRTLQNNIESLNKEKQKLEEDCQSLEKKLSQTRRDLTATEDSIKTALSNVEKRELDIKNLQQEIDVLNKQKKSLHGDITVVQKDLQEKKNELEMLKGELSESRQQLQLAEQNLKDNTKHQEELLREQATLKEDILKCVRKCKDCQERQKKRENHLQQLQKEIEEKETILAKQEAILCNLKQNSEHEGKKLEENTAKLKEQKLLLEKELMDQREKLEQAVAKVRLTEENNRKLEKEASQFAALEETIRKSKHQVSEKELQLQQKNREIQSLQKELELSKSELNHLQGQLASERKRAEKRICSLKEAMKMQRTQFERELHEQKRENNCLQSDIAAAEQVAQNNHERTKRLIKELGQIQQDYMDLQNQVKTQEDLEKRQREIENTATLLKLEVEDDIKTGFKSSSPSSPELLEDLEAFSAVNKSLQCESDNLEEMFSFADADKRLFSSEKKLDFSQIFIMDEQWRGEALREKLQHHEDRLKAQLRHCMSKQVDVLIRGKQQTQGTLHSLKRQVDALDDLVSSTSSDSLFLAESSSSLLSLRDALSLTKTQAALTGHAHFPSSSAGVPAVAHTWHSCS", "length": 2179, "header": "tr|A0A8V1ACP7-1|A0A8V1ACP7_CHICK Computationally mapped isoform of Centriolin OS=Gallus gallus OX=9031 GN=CNTRL PE=4 SV=1 CANONICAL=A0A8V1A9Y6-1" }, "locus": { "chromosome": "17", "start_pos": 8984021, "end_pos": 8955114, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067092.1", "url": "https://www.ensembl.org/id/ENSGALT00010067092.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041013.1", "url": "https://www.ensembl.org/id/ENSGALP00010041013.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:417121", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417121", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A1B0GWU0-1", "protein_name": "Centriolin", "gene_name": "Cntrl", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKKGSERKLSKAKMPVSSHFPGPSSLRSSMRSRSLSPLIGSETPPFHPGGQCPAQAELTDENTMPLESQQHKGADPYVGVRYITEALIKKLTKQDNLALVKSLNLSLSKDGGKKFRYIENLEKCVKLEVLNLSYNLIAKIEKVDKLLRLRELNLSYNKISKIEGLENMCNLQKLNLAGNEIEHIPGWFSKKLKSLRVLNLKGNKISSLQDVSKLKPLQDLTSLTLIDNPVVALPHYLQFIIFHLRSLESLEGQPVTTQDRQEAFERFSLEEIERLEKDLEKKTVETEELKNKQTKFLEEIKHQDKLNKSLKEEAMLQKQSCEELESDLNTKKELLKQKTVELTRACQKQYELEQELAFYKIDAKFEPLNYYPSEYAEMDKSPDESPYIGKSRYKRNMFATETYIVSDAQAVQVRKMVPDGGQLRHEHAPRAQAPPDVQLEDTGKQIVAAQTRLSELHHEIEAAEQKVLRATQEFKQLEEAIRQKKISEAEKDLLLKQLSGRLRHLNKLRQEALDLEAQLEKQRKEIAEKHEEINSAQLATDLLDSKDPKQSHMKAQKRGKEQQLDIMNKQYTQLESRLDEILCRIATETEEIKDLEQQLTDGQIAANEALKKDLEGVISGLQEYLGTIKGQAAQAQNECRKLQDEKETLLQRLTEVKQEKDELEIVAMDAENMRKELAELENALQEQHEVNASLQQAQGDLSAYETELETQLKLKDAETSQLKQELENLVRRTQLEQSVLQTELEKERQSLRDALGKAQSSEEKQQENSELRAQLKQLQDDNSLLKKQLKDFQSHLNHVVDGLIHPEEVAARVDELRKRLKLGAGEMRIHSPSDVLGKSLADLQKQFSEILARSQWEKEEAQVRERKLHEEMALQQEKLANGQEEFKQACERALEARIKFDKRQHNARIQQLENEIHYLQENLKSMEKIQGLTDLQLQEADEEKERILAQLQELEKKKRREDARSQEQFLGLDTELKSLKKAVAASDKLAAAELTIAKEQLKSLHGTVMRINQERAEELQEAERSSREAMQAAKDLSRAEAEIELLQHLLREREGQFRDEMENAHVGSKGANLQLLEIEALKEAMAKQRAEITRLRDVLNLTGTGKKGGIENVVEEIAELRHAVSAQNEYISSMADPVQRQGCWYFMPPPPSSKVSSHSSQATKDSGLGLKCTASTPLRSQQAGQQEEKGSSGPLPASGYWVYSPIRSTPHKSFSKREDADNGGDSQEESGLDDQEDPPFVPPPGYIMYTVLPDGSPVPQGVALYAPSPPLPHSSHPLTPGTVVYGPPPAGAPIIYGPPPANFAVPLISMGVQHCNIPEHRDLENEVSRLEDITHHLKSKHQEERWLKTSRQHPEKEVEELHRNIDDLVQEKKELELEVEELHRTVERHQQRRDFIDGNVENLMTELEIEKSLKHHEDIVDEIECLEKTLLKRRSELREADRLLAEAESELACTKEKTKSAVEKFTDAKRNLLQTESDAEALEKRAQETALNLVKAEQQLRLLQADAEDLEQHKIKQEEILKEINKVVAAKDADFQCLNEKKEKLTEELQSLQRDIKAAEVNEDHHLQVLKESESLLQAKRAELETLKSQVTSQQQELAVLDSQLGHRREELLLLQDSLTQAKADLQEALTLGETEVAEKCSHIREVKSLLEELSFQKGELNVHISERRTQLTLIKQEIEKEEENLEVVLQQLSKHKTELKNVADILQLETNELQSLKLQHDQKVVELEKTQVDLLEGKLELESLQQTAQQQRRELERQRQLLERDRRETERVRAETQALQSCIECLNKEKEHLQEQCESWEKKSSHAKRVLAATEESNNTEQSKLGQLEVSVRKLQQELELLSQDKLALHSDSAQEQQQLQDKREALNSLQKELENTQDHLNLAKQDLMHTTKCQSALLSEQAQLQKDVSQWTARLESCQKETETKEQQLQELQDEIRESKLQLDQQEMVFQKLQKERESEEQKLVASIVSLEQQQGQLERELMDQKSKLEWLLTDVSAAEGRLRTLQKEERCTESLEKMLSQAKQQLSEREQQLMEKSGDLLALQKEADGMRADFSLLRNQFLTERKKAEKQVAGLKEALKIQRSQLEKNLLEQKQENSCMQKEMATIELVAQDNHERARRLMKELRQMQQEYLELKKQVANQKDFERRQMEVSNAMRTLKSEVKDEIRTSLRNLNQFLPDLPADLTAILERDDNLRELESVKENFPFTTNERIFEEKSNFPQVHIMDEHRRGEALRERLRHREDHLKAQLRDSMSKQAEVLIKGKRQTEGTLHSLRRQVDALGELVTSTSVDSAPSPSLSHLESSLVEDSQHGHSQSSFQVLQVPSEPNIYRH", "length": 2336 }, "evidence": [ { "id": "A0A8V1A9Y6", "url": "https://omabrowser.org/oma/group/A0A8V1A9Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A9J7JV20-1", "protein_name": "Centriolin", "gene_name": "Cntrl", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MKRGSEQTFSKAKMSLSSHFSGPSSLMPSMRSRSLSPLIVSETPPFHSGGEWSAQAGLTDENTMLLESQHHKGSDSCVGVRYITEALIKKLTKQDNLTLVKSLNLSLSKDGGKKFRYIENLDKCVKLEVLNLSYNLIAKIEKVDKLLRLRELNLSYNKISKIEGLENMFNLQKLNLAGNEIQHIPVWLAKKLKSLRVLNLKGNKISSLQDVSKLKPLQDLTSLTLIDNPLATLPHYLQFTIFHLRSLESLEGQPVTTQDRQEAFERFSLEEVERLEKDLEKKMVETDELKNKQTKFLEEIKNQDKLNKSLKEEAMLQKQNCEELESDLNTKNELLKQKTMELTRACQKQYELEQELAFYKIDAKFEPLNYYPSEYAEIDKPPDESPYIGKSRYKRNMFATETYILSDAQAVQIQKMMPGGQLRHEHVPLRAHALLDVQVEDTEKNISAAQIRLSELHHEIETAEQKILQATQEFKQLEEAIQQKKLSEAEKDLLLKQLSSRIQFLNKLRQEALDLEMQMEKQRKETAEKQEDINNLQLAIDSLDFKDPKHSHMKAQKRGKEQQLDIMNKQYTQLESRLNEILSRIAKETEEIKDLEQQLTDGQIAANEALKKDLEGVISGLQEYLGTIKGQATQAQNECRKLQDEKETLLQRLTDVKQERDELEIVAIDAENMRKELAELESALQEQREMNASLQQAQGELSAYEAELETRLKLKDAEASQLKGELEKLTRLTQLEQSVLQTELEKERESLRDALGKAQSSEEKQQENSELRTQLKKLQDDNSLLKQQLKDFQKHLNQVVDGLIHPEEVAARVDELRRKLKLGAGEMRIHSPSDVLGKSLANLQKQFSEILARSQWEKEEAQVRERKLHEEMVLQQETLANGQEEFRQACERALEARVKFDKRQHNARIQQLENEIHYLQENLKSMEEIQGLTDLQLQEADEEKERIMAQLQELEKKKKHEDAKSQEQFLGLDKELKSLKKAVAASDKLAAAELTITKDQLKSLHGTVMRINQERAEELQKAEKLGRKATQAAKDLARAEAEIELLQHLLREREEQFCIKMENADLGSKGANSQLLEIKMLNEVMAKQRAEITRLRDVLNLTGTGDKGGGIENVLEEIAELRHEVSAQNEYISSMTDPFRRQGYWCFIPPPPPSSKVSSHSSQVTKDSGLGLKYTASTPLRKPQPGQQEEKDNSEPLPTSGYWVYSPIRNGLHKSFSNRENADSGGDSQEESGLDDQEEPSFVPPPGYIMYTVFPDGSPVPQGMALYAPSPPLPNNSQPLTPGTVVYGPPPVGAPIVYGPPPTNFAVPLVPVGMQHCNIPEHHNLLNEVSRLEDIMQHLKSNRQEEQWPKASKQHSEKEVEELHHNIDDLLQEKKELEHEVEELHRTIQKHQQRKDFIDGNVENLMTELEIEKSLKRHEDIVDEVACIEKTLLKRRSELREADQLLAEAEHELSCTKEKTKHAVEKFADAERNLLQIESDAEALEKRAQETALNLVKAEQQLRLLQADAEDLEQHKIKQEEILKEINKVVAAKDADFQCLNEKKEKLTKDLQSLQRDIKTAEHNEDHHLQVLKDSETLLQAKRAELETLRSQVTSQQQELAVLDTQLRHRREELLLLQDSLVQAKADLQEALTLGETEVAEKCSHIREVKSLLEELSFQKGELNVHISEQKTQLALIKQEMEKEEENLQIVLQQLSKHKTELKNLAEILQLENSELQGLKLQRDQKVMELEKTQVDLLEEKLELENLQQTIQQQNREIEWQKQLLERDKREIERVRAETQALRSCIECLTKEKEDLQEQCEAWEKKSSQAKRVLATTEESNRTEQSNLGKLEHRVRELQQELEHLSQDKLAMHSDISMVQHQLQDKREAINSLQEELGNTQDHLNQAKQDLLHTTQRQNALLSEQEQLQKDISKWIARFESCQKETETKEQQLQELQNEIRESKLQLEQQEMMFQKLQKETESEEQKLEAGKVTLKQQQEQLEKEVTEQKTKLEQLLTDVSAAEGRLRTLQEEGRCSESLEKLLSQAKQQLSEREQQLIGKSSELLAQQEEADAMRADFSLLRNQFLTERKKAEKQVAGLKEALKFQRSQLEKNLLEQRQENSCMQKEMATIELVAQDNHERARRLMKELNQMQHEYLELKKQMANQKDLERRQMEINDAMRTLKSEVKDEIRTSLKNFNQFLPELPADLTAILERNENLGELESLKENFPFTTNERLFEEKSNFSQIHIMDEHWRGEALRERLRHREDRLKAQLRHCMSKQAEVLIKGKRQTEGTLHSLRRQVDALGELVTSSSVDSTSPPSLSHLDSSLVEDSQIGQSREKKLQLKSGIWSCVNLRGNTYSTSLTS", "length": 2348 }, "evidence": [ { "id": "A0A8V1A9Y6", "url": "https://omabrowser.org/oma/group/A0A8V1A9Y6/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A2AL36-1", "protein_name": "Centriolin", "gene_name": "Cntrl", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKKGSERRLSKAKMPLSSHFPGPSSLRSSMRSRSLSPLIGSETQPLHPGGQWPAQAELTDESTVPLEPQQRKGAESYVGVRYITEALIKKLTKQDNLALVKSLNLSLSKDGGKKFRYIENLEKCVKLEVLNLSYNLIVKIEKVDKLLRLRELNLSYNKISKIEGLENMCNLQKLNLAGNEIEHIPVWFAKKLKSLRVLNLKGNKISSLQDVSKLKPLQDLTSLVLIDNPVVALPHYLQFIIFHLRSLESLEGQPVTTQDRQEAFERFSLEEIERLEKDLEKKTVETEELKNKQTKFLEEIKNQDKLNKSLKEEAMLQKQSCEELESDLSTKKELLKQKTVELTRACQKQYELEQELAFYKIDAKFEPLNYYPSEYAEIDKYPDESPYIGKSRYKRNMFATETYIVSDAQAVQIRKMVPEGGQLRHEHTPPRVQAPPDLQLEDTEKKISAAQTRLSELHHEIETAEQKVLRATQEFKQLEEAIQQKKISEAEKDLLLKQLSGRLQHLNRLRQEALDLEIQMEKQRKEIAEKHEEINTVQLATDSLDPKDPKHSHMKAQKRGKEQQLDIMNRQYTQLESRLDEILCRIAKETEEIKDLEQQLTDGQIAANEALKKDLEGVISGLQEYLGTIKGQATQAQNECRKLQDEKETLLQRLTEVQQEKEELELIAMDAENMRKELAELESALQEQHEVNASLQQAQGDLSAYETELETQLKLKDAETSQLKQELEKLLRRTQLEQSVLQTELEKERESLRDALGKAQSSEEKQQENNELRTQLKQLQDDNSLLKKQLKEFQNHLNHVVDGLIHPEEVAARVDELRKRLKLGAGEMRIHSPSDVLGKSLADLQKQFSEILARSQWEKEEAQVRERKLHEEMALQQEKLANGQEEFRQACERALEARIKFDKRQHNARIQQLENEIHYLQENLKSMEKIQGLTDLQLQEADEEKERILAQLQELEKKKKREDARSQEQFLGLDEELKSLKKAVAASDKLAAAELTIAKDQLKSLHGTVVRINQERAEELQEAERFSREAMQAAKDLSRAEAEIELLQHLLREREGQFRDEMENADLGAKGANSQLLEIEALNEAMAKQRAEITRLRDVLNLTGAGTKGGIENVLEEIAELRHAVSAQNEYISSMADPFRRQGWWYFMPPAPSSKVSSHSSQATKDSGLGLKYTASTPLRKPQPGQQEEKDSSGPLPASGYWVYSPIRSTLHKSFSKREDADSGGDSQEESGLDDQEEPPFVPPPGYIMYTVLPDGSPVPQGVALYAPSPPLPNSSHPLTPGTVVYGPPPAGAPIIYGPPPANFAVPLVPAGVQHCNIPEHHNLENEVSRLEDIMQHLKSKQREERRQKASTQHSEEEVDGLHRDIDDLLQEKKELELEVEELHRTIERHQQRKDFIDGHVENLMTELEIEKSLKHHEDIVDEIECLEKTLLKRRSELREADRLLAEAENELACTKEKTKSAVEKFTDAKRNLLQTESDAEALEKRAQETALNLVKAEQQLRLLQADAEDLEQHKIKQEEILKEINKVVAAKDADFQCLNEKKEKLTEELQSLQRDIKAAQHSEDHHLQVLRESETLLQAKRAELETLKSQVTSQQQELAVLDSELGHRREELLLLQDSLAQAKADLQEALTLGETEVAEKCSHIREVKSLLEELSFQKGELNVHISEKKTQLALIQQEMEKEEKNLQVVLQQLSRHKTELKNVADILQLETSELQGLKLQHDQKVVELEKAQVDVLEEKLELENLQQATQQQRRELERQRQLLERDRRETERVRAESQALQSCVECLSKEKEDLQGQCESWEKKSSHAQRVLAATEESNKMEQSNLGKLELSVRKLRQELEQLSQDKLALHSEVAEVQQQLQGKQEAINSLQEELDSTQDHLDLAKQDLIHTTKCQNELLNEQTQLQEDISKWMARLESCQKETETKEQQVQQLQDEIRESKLRLDQQEMMFQKLQKEREREEQKFEAGKVTLEQQQRQLEKELTDQKSRLKQLLTDVSAAEGRLGTLQEEERRIEGLERMLSQAKQQLSEREQQLMAKSGELLALQKEADDMRADFSLLRNQFLTERKKAEKQVAGLKEALKIQRSQLEKNLLEQKQENSCMQKEMATIELVAQDNHERARRLMKELSQMQQEYLELKKQVANQKDLERRQMEVSDAMRTLKSEVKDEIRTSLRNLNQFLPELPADLASILERNENLRELESLKENFPFTTKERIFEEKSNFPQVHIMDEHWRGEALRQRLRRHEDQLKAQLRHCMSKQAEVLIKGKQQTEGTLHSLRRQVDALGELVTSTSTDSASSPSLPSLVEDSQHGHSQSSFQVLQVPLEEPNSYRH", "length": 2334 }, "evidence": [ { "id": "A0A8V1A9Y6", "url": "https://omabrowser.org/oma/group/A0A8V1A9Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7Z7A1-1", "protein_name": "Centriolin", "gene_name": "CNTRL", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKKGSQQKIFSKAKIPSSSHSPIPSSMSNMRSRSLSPLIGSETLPFHSGGQWCEQVEIADENNMLLDYQDHKGADSHAGVRYITEALIKKLTKQDNLALIKSLNLSLSKDGGKKFKYIENLEKCVKLEVLNLSYNLIGKIEKLDKLLKLRELNLSYNKISKIEGIENMCNLQKLNLAGNEIEHIPVWLGKKLKSLRVLNLKGNKISSLQDISKLKPLQDLISLILVENPVVTLPHYLQFTIFHLRSLESLEGQPVTTQDRQEAFERFSLEEVERLERDLEKKMIETEELKSKQTRFLEEIKNQDKLNKSLKEEAMLQKQSCEELKSDLNTKNELLKQKTIELTRACQKQYELEQELAFYKIDAKFEPLNYYPSEYAEIDKAPDESPYIGKSRYKRNMFATESYIIDSAQAVQIKKMEPDEQLRNDHMNLRGHTPLDTQLEDKEKKISAAQTRLSELHDEIEKAEQQILRATEEFKQLEEAIQLKKISEAGKDLLYKQLSGRLQLVNKLRQEALDLELQMEKQKQEIAGKQKEIKDLQIAIDSLDSKDPKHSHMKAQKSGKEQQLDIMNKQYQQLESRLDEILSRIAKETEEIKDLEEQLTEGQIAANEALKKDLEGVISGLQEYLGTIKGQATQAQNECRKLRDEKETLLQRLTEVEQERDQLEIVAMDAENMRKELAELESALQEQHEVNASLQQTQGDLSAYEAELEARLNLRDAEANQLKEELEKVTRLTQLEQSALQAELEKERQALKNALGKAQFSEEKEQENSELHAKLKHLQDDNNLLKQQLKDFQNHLNHVVDGLVRPEEVAARVDELRRKLKLGTGEMNIHSPSDVLGKSLADLQKQFSEILARSKWERDEAQVRERKLQEEMALQQEKLATGQEEFRQACERALEARMNFDKRQHEARIQQMENEIHYLQENLKSMEEIQGLTDLQLQEADEEKERILAQLRELEKKKKLEDAKSQEQVFGLDKELKKLKKAVATSDKLATAELTIAKDQLKSLHGTVMKINQERAEELQEAERFSRKAAQAARDLTRAEAEIELLQNLLRQKGEQFRLEMEKTGVGTGANSQVLEIEKLNETMERQRTEIARLQNVLDLTGSDNKGGFENVLEEIAELRREVSYQNDYISSMADPFKRRGYWYFMPPPPSSKVSSHSSQATKDSGVGLKYSASTPVRKPRPGQQDGKEGSQPPPASGYWVYSPIRSGLHKLFPSRDADSGGDSQEESELDDQEEPPFVPPPGYMMYTVLPDGSPVPQGMALYAPPPPLPNNSRPLTPGTVVYGPPPAGAPMVYGPPPPNFSIPFIPMGVLHCNVPEHHNLENEVSRLEDIMQHLKSKKREERWMRASKRQSEKEMEELHHNIDDLLQEKKSLECEVEELHRTVQKRQQQKDFIDGNVESLMTELEIEKSLKHHEDIVDEIECIEKTLLKRRSELREADRLLAEAESELSCTKEKTKNAVEKFTDAKRSLLQTESDAEELERRAQETAVNLVKADQQLRSLQADAKDLEQHKIKQEEILKEINKIVAAKDSDFQCLSKKKEKLTEELQKLQKDIEMAERNEDHHLQVLKESEVLLQAKRAELEKLKSQVTSQQQEMAVLDRQLGHKKEELHLLQGSMVQAKADLQEALRLGETEVTEKCNHIREVKSLLEELSFQKGELNVQISERKTQLTLIKQEIEKEEENLQVVLRQMSKHKTELKNILDMLQLENHELQGLKLQHDQRVSELEKTQVAVLEEKLELENLQQISQQQKGEIEWQKQLLERDKREIERMTAESRALQSCVECLSKEKEDLQEKCDIWEKKLAQTKRVLAAAEENSKMEQSNLEKLELNVRKLQQELDQLNRDKLSLHNDISAMQQQLQEKREAVNSLQEELANVQDHLNLAKQDLLHTTKHQDVLLSEQTRLQKDISEWANRFEDCQKEEETKQQQLQVLQNEIEENKLKLVQQEMMFQRLQKERESEESKLETSKVTLKEQQHQLEKELTDQKSKLDQVLSKVLAAEERVRTLQEEERWCESLEKTLSQTKRQLSEREQQLVEKSGELLALQKEADSMRADFSLLRNQFLTERKKAEKQVASLKEALKIQRSQLEKNLLEQKQENSCIQKEMATIELVAQDNHERARRLMKELNQMQYEYTELKKQMANQKDLERRQMEISDAMRTLKSEVKDEIRTSLKNLNQFLPELPADLEAILERNENLEGELESLKENLPFTMNEGPFEEKLNFSQVHIMDEHWRGEALREKLRHREDRLKAQLRHCMSKQAEVLIKGKRQTEGTLHSLRRQVDALGELVTSTSADSASSPSLSQLESSLTEDSQLGQNQEKNASAR", "length": 2325 }, "evidence": [ { "id": "A0A8V1A9Y6", "url": "https://omabrowser.org/oma/group/A0A8V1A9Y6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "meiotic spindle pole", "id": "GO:0090619", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090619", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9Y6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9Y6" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9Y6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9Y6" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9Y6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9Y6" } ], 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"summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046757650" }, "gene_names": [ { "name": "FBXW2", "type": "recommended", "evidence": [ { "id": "A0A8V1A9Z5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9Z5" } ] }, { "name": "FBXW2", "type": "synonym", "evidence": [ { "id": "XP_046757650", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046757650" } ] } ], "protein_names": [ { "name": "F-box/WD repeat-containing protein 2", "type": "recommended", "evidence": [ { "id": "A0A8V1A9Z5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9Z5/entry#names_and_taxonomy" } ] }, { "name": "F-box and WD-40 domain-containing protein 2", "type": "synonym", "evidence": [ { "id": "A0A8V1A9Z5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9Z5/entry#names_and_taxonomy" } ] }, { "name": "F-box/WD repeat-containing protein 2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_046757650", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046757650" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052548.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_046757650", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046757650" } ] }, { "annotation": "Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHI3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHI3#function" }, { "database": "UniProtKB", "id": "ARBA00003437", "url": "https://www.uniprot.org/uniprotkb/ARBA00003437#function" }, { "database": "UniProtKB", "id": "A0A8V1A9Z5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9Z5#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9Z5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9Z5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FBXW2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9Z5", "locus": { "chromosome": "17", "start_pos": 10982016, "end_pos": 11002582, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028712", "url": "https://www.ensembl.org/id/ENSGALG00010028712" } ] } } ], "crossref": [ { "id": "A0A8V1A9Z5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1A9Z5", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd22131", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22131", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "417088", "url": "https://www.ncbi.nlm.nih.gov/gene/417088", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001810", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001810", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019775", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019775", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020472", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020472", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036047", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036047", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042627", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042627", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "TIACWDW", "url": "https://omabrowser.org/oma/group/TIACWDW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A9Z5", "url": "https://www.orthodb.org/?gene=A0A8V1A9Z5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AFA0", "url": "https://www.orthodb.org/?gene=A0A8V1AFA0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AHI3", "url": "https://www.orthodb.org/?gene=A0A8V1AHI3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ALI3", "url": "https://www.orthodb.org/?gene=A0A8V1ALI3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR44436", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44436", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR44436:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44436:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00400", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00400", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12937", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12937", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-8951664", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8951664", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-983168", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983168", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_046757650", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046757650", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1A9Z5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9Z5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A9Z5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9Z5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFA0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFA0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFA0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFA0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHI3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHI3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHI3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHI3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALI3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALI3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALI3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALI3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSFNTILQTSLCIFFKHKAGKFLHNLMEKKDFEAWLDNISITFLSLTDLQKNETLDHLISLSGAVQLRHLSNNLEILLKRDFLKLLPLELSFYLLKWLDPHTLLTCCLVSKQWNKVISACTEVWQTACKNLGWQIDDSVQDPLHWKKVYLKAILRMKQLKDHEAFETSSLIGHSARVYALYYRDGLLCTGSDDLSAKLWDVSTGQCIYGIQTHTCATVKFDEQKLVTGSFDNTVACWEWSSGAKTQHFRGHTGAVFSVDYNDELDVLVSGSADFTVKVWALSTGTCLNTLTGHTEWVTKVVLQKCKVKSLMHSPGDYILLSADKYEIKIWPIGREINCKCLKTLSVSEDRSISLQPRLHFDGKYIVCSSALGLYQWDFASYDIVRVIKTSDFSNVSLLGFGEIFALLFDNRYLYIMDVRTEELISRWPLPEYRKSKRGSSFLAGEMSWLNGLNGQNDTGLVFATSMPDHSIHLVLWKEHG", "length": 480, "header": "tr|A0A8V1A9Z5-1|A0A8V1A9Z5_CHICK Isoform 1 of F-box/WD repeat-containing protein 2 OS=Gallus gallus OX=9031 GN=FBXW2 PE=4 SV=1 CANONICAL=A0A8V1A9Z5-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A9Z5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9Z5/entry#A0A8V1A9Z5-1", "sequence": { "sequence": "MSFNTILQTSLCIFFKHKAGKFLHNLMEKKDFEAWLDNISITFLSLTDLQKNETLDHLISLSGAVQLRHLSNNLEILLKRDFLKLLPLELSFYLLKWLDPHTLLTCCLVSKQWNKVISACTEVWQTACKNLGWQIDDSVQDPLHWKKVYLKAILRMKQLKDHEAFETSSLIGHSARVYALYYRDGLLCTGSDDLSAKLWDVSTGQCIYGIQTHTCATVKFDEQKLVTGSFDNTVACWEWSSGAKTQHFRGHTGAVFSVDYNDELDVLVSGSADFTVKVWALSTGTCLNTLTGHTEWVTKVVLQKCKVKSLMHSPGDYILLSADKYEIKIWPIGREINCKCLKTLSVSEDRSISLQPRLHFDGKYIVCSSALGLYQWDFASYDIVRVIKTSDFSNVSLLGFGEIFALLFDNRYLYIMDVRTEELISRWPLPEYRKSKRGSSFLAGEMSWLNGLNGQNDTGLVFATSMPDHSIHLVLWKEHG", "length": 480, "header": "tr|A0A8V1A9Z5-1|A0A8V1A9Z5_CHICK Isoform 1 of F-box/WD repeat-containing protein 2 OS=Gallus gallus OX=9031 GN=FBXW2 PE=4 SV=1 CANONICAL=A0A8V1A9Z5-1" }, "locus": { "chromosome": "17", "start_pos": 10990395, "end_pos": 10983632, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069505.1", "url": "https://www.ensembl.org/id/ENSGALT00010069505.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042787.1", "url": "https://www.ensembl.org/id/ENSGALP00010042787.1" } ] } }, { "isoform_ac": "A0A8V1AFA0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9Z5/entry#A0A8V1AFA0-1", "sequence": { "sequence": "MEKKDFEAWLDNISITFLSLTDLQKNETLDHLISLSGAVQLRHLSNNLEILLKRDFLKLLPLELSFYLLKWLDPHTLLTCCLVSKQWNKVISACTEVWQTACKNLGWQIDDSVQDPLHWKKVYLKAILRMKQLKDHEAFETSSLIGHSARVYALYYRDGLLCTGSDDLSAKLWDVSTGQCIYGIQTHTCATVKFDEQKLVTGSFDNTVACWEWSSGAKTQHFRGHTGAVFSVDYNDELDVLVSGSADFTVKVWALSTGTCLNTLTGHTEWVTKIWPIGREINCKCLKTLSVSEDRSISLQPRLHFDGKYIVCSSALGLYQWDFASYDIVRVIKTSDFSNVSLLGFGEIFALLFDNRYLYIMDVRTEELISRWPLPEYRKSKRGSSFLAGEMSWLNGLNGQNDTGLVFATSMPDHSIHLVLWKEHG", "length": 425, "header": "tr|A0A8V1AFA0-1|A0A8V1AFA0_CHICK Computationally mapped isoform of F-box and WD repeat domain containing 2 OS=Gallus gallus OX=9031 GN=FBXW2 PE=4 SV=1 CANONICAL=A0A8V1A9Z5-1" }, "locus": { "chromosome": "17", "start_pos": 10989855, "end_pos": 10983632, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069510.1", "url": "https://www.ensembl.org/id/ENSGALT00010069510.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042789.1", "url": "https://www.ensembl.org/id/ENSGALP00010042789.1" } ] } }, { "isoform_ac": "A0A8V1AHI3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9Z5/entry#A0A8V1AHI3-1", "sequence": { "sequence": "MPELGAHTAPAPGKFLHNLMEKKDFEAWLDNISITFLSLTDLQKNETLDHLISLSGAVQLRHLSNNLEILLKRDFLKLLPLELSFYLLKWLDPHTLLTCCLVSKQWNKVISACTEVWQTACKNLGWQIDDSVQDPLHWKKVYLKAILRMKQLKDHEAFETSSLIGHSARVYALYYRDGLLCTGSDDLSAKLWDVSTGQCIYGIQTHTCATVKFDEQKLVTGSFDNTVACWEWSSGAKTQHFRGHTGAVFSVDYNDELDVLVSGSADFTVKVWALSTGTCLNTLTGHTEWVTKVVLQKCKVKSLMHSPGDYILLSADKYEIKIWPIGREINCKCLKTLSVSEDRSISLQPRLHFDGKYIVCSSALGLYQWDFASYDIVRVIKTSDFSNVSLLGFGEIFALLFDNRYLYIMDVRTEELISRWPLPEYRKSKRGSSFLAGEMSWLNGLNGQNDTGLVFATSMPDHSIHLVLWKEHG", "length": 473, "header": "tr|A0A8V1AHI3-1|A0A8V1A9Z5_CHICK Computationally mapped isoform of F-box/WD repeat-containing protein 2 OS=Gallus gallus OX=9031 GN=FBXW2 PE=4 SV=1 CANONICAL=A0A8V1A9Z5-1" }, "locus": { "chromosome": "17", "start_pos": 11002523, "end_pos": 10983632, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069512.1", "url": "https://www.ensembl.org/id/ENSGALT00010069512.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042791.1", "url": "https://www.ensembl.org/id/ENSGALP00010042791.1" } ] } }, { "isoform_ac": "A0A8V1ALI3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9Z5/entry#A0A8V1ALI3-1", "sequence": { "sequence": "MEKKDFEAWLDNISITFLSLTDLQKNETLDHLISLSGAVQLRHLSNNLEILLKRDFLKLLPLELSFYLLKWLDPHTLLTCCLVSKQWNKVISACTEVWQTACKNLGWQIDDSVQDPLHWKKVYLKAILRMKQLKDHEAFETSSLIGHSARVYALYYRDGLLCTGSDDLSAKLWDVSTVACWEWSSGAKTQHFRGHTGAVSGSADFTVKVWALSTGTCLNTLTGHTEWVTKVVLQKCKVKSLMHSPGDYILLSADKYEIKIWPIGREINCKCLKTLSVSEDRSISLQPRLHFDGKYIVCSSALGLYQWDFASYDIVRVIKTSDFSNVSLLGFGEIFALLFDNRYLYIMDVRTEELISRWPLPEYRKSKRGSSFLAGEMSWLNGLNGQNDTGLVFATSMPDHSIHLVLWKEHG", "length": 411, "header": "tr|A0A8V1ALI3-1|A0A8V1A9Z5_CHICK Computationally mapped isoform of F-box/WD repeat-containing protein 2 OS=Gallus gallus OX=9031 GN=FBXW2 PE=4 SV=1 CANONICAL=A0A8V1A9Z5-1" }, "locus": { "chromosome": "17", "start_pos": 10989855, "end_pos": 10983632, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069509.1", "url": "https://www.ensembl.org/id/ENSGALT00010069509.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042788.1", "url": "https://www.ensembl.org/id/ENSGALP00010042788.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-8951664", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8951664", "resource": "Reactome", "description": "Neddylation" }, { "id": "R-GGA-983168", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983168", "resource": "Reactome", "description": "Antigen processing: Ubiquitination & Proteasome degradation" } ], "orthologs": [ { "uniprot_canonical_ac": "B2RZ17-1", "protein_name": "F-box/WD repeat-containing protein 2", "gene_name": "Fbxw2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MERKDFETWLDNISVTFLSLTDLQKNETLDHLISLSGAVQLRHLSNNLETLLKRDFLKLLPLELSFYLLKWLDPQTLLTCCLVSKQWNKVISACTEVWQTACKNLGWQIDDSVQDALHWKKVYLKAILRMKQLEDHEAFETSSLIGHSARVYALYYKDGLLCTGSDDLSAKLWDVSTGQCVYGIQTHTCAAVKFDEQKLVTGSFDNTVACWEWSSGARTQHFRGHTGAVFSVDYSDELDILVSGSADFAVKVWALSAGTCLNTLTGHTEWVTKVVLQQCKVKSLLHSPGDYILLSADKYEIKIWPIGREINCKCLKTLSVSEDRSICLQPRLHFDGKYIVCSSALGLYQWDFASYDILRVIKTPEVANLALLGFGDVFALLFDNHYLYIMDLRTESLISRWPLPEYRKSKRGSSFLAGEASWLNGLDGHNDTGLVFATSMPDHSIHLVLWKEHG", "length": 454 }, "evidence": [ { "id": "A0A8V1A9Z5", "url": "https://omabrowser.org/oma/group/A0A8V1A9Z5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q58D00-1", "protein_name": "F-box/WD repeat-containing protein 2", "gene_name": "FBXW2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MERKDFETWLDNISVTFLSLTDLQKNETLDHLISLSGAVQLRHLSNNLETLLKRDFLKLLPLELSFYLLKWLDPQTLLTCCLVSKQWNKVISACTEVWQTACKSLGWQIDDSVQDALHWKKVYLKAILRMKQLEDHEAFETSSLIGHSARVYALYYKDGLLCTGSDDLSAKLWDVSTGQCVYGIQTHTCAAVKFDEQKLVTGSFDNTVACWEWSSGARTQHFRGHTGAVFSVDYNDELDILVSGSADFTVKVWALSAGTCLNTLTGHTEWVTKVVLQKCKVKSLLHSPGDYILLSADKYEIKIWPIGREINCKCLKTLSVSEDRSICLQPRLHFDGKYIVCSSALGLYQWDFASYDILRVIKTPEIANLALLGFGDIFALLFDNRYLYILDLRTESLISRWPLPEYRKSKRGSSFLAGEASWLNGLDGHNDTGLVFATSMPDHSIHLVLWKEHG", "length": 454 }, "evidence": [ { "id": "A0A8V1A9Z5", "url": "https://omabrowser.org/oma/group/A0A8V1A9Z5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q60584-1", "protein_name": "F-box/WD repeat-containing protein 2", "gene_name": "Fbxw2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MERKDFETWLDNISVTFLSLTDLQKNETLDHLISLSGAVQLRHLSNNLETLLKRDFLKLLPLELSFYLLKWLDPQTLLTCCLVSKQWNKVISACTEVWQTACKNLGWQIDDSVQDSLHWKKVYLKAILRMKQLEDHEAFETSSLIGHSARVYALYYKDGLLCTGSDDLSAKLWDVSTGQCVYGIQTHTCAAVKFDEQKLVTGSFDNTVACWEWSSGARTQHFRGHTGAVFSVDYSDELDILVSGSADFAVKVWALSAGTCLNTLTGHTEWVTKVVLQKCKVKSLLHSPGDYILLSADKYEIKIWPIGREINCKCLKTLSVSEDRSICLQPRLHFDGKYIVCSSALGLYQWDFASYDILRVIKTPEVANLALLGFGDVFALLFDNHYLYIMDLRTESLISRWPLPEYRKSKRGSSFLAGERPG", "length": 422 }, "evidence": [ { "id": "A0A8V1A9Z5", "url": "https://omabrowser.org/oma/group/A0A8V1A9Z5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9UKT8-1", "protein_name": "F-box/WD repeat-containing protein 2", "gene_name": "FBXW2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MERKDFETWLDNISVTFLSLTDLQKNETLDHLISLSGAVQLRHLSNNLETLLKRDFLKLLPLELSFYLLKWLDPQTLLTCCLVSKQWNKVISACTEVWQTACKNLGWQIDDSVQDALHWKKVYLKAILRMKQLEDHEAFETSSLIGHSARVYALYYKDGLLCTGSDDLSAKLWDVSTGQCVYGIQTHTCAAVKFDEQKLVTGSFDNTVACWEWSSGARTQHFRGHTGAVFSVDYNDELDILVSGSADFTVKVWALSAGTCLNTLTGHTEWVTKVVLQKCKVKSLLHSPGDYILLSADKYEIKIWPIGREINCKCLKTLSVSEDRSICLQPRLHFDGKYIVCSSALGLYQWDFASYDILRVIKTPEIANLALLGFGDIFALLFDNRYLYIMDLRTESLISRWPLPEYRKSKRGSSFLAGEASWLNGLDGHNDTGLVFATSMPDHSIHLVLWKEHG", "length": 454 }, "evidence": [ { "id": "A0A8V1A9Z5", "url": "https://omabrowser.org/oma/group/A0A8V1A9Z5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 38, "end_pos": 40, "annotation": "n_glycosylation_sequon" }, { "start_pos": 394, "end_pos": 396, "annotation": "n_glycosylation_sequon" }, { "start_pos": 456, "end_pos": 458, "annotation": "n_glycosylation_sequon" }, { "start_pos": 52, "end_pos": 54, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1A9Z5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9Z5" }, { "id": "PS50181", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50181" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "F-box", "eco_id": "ECO_0000259", "start_pos": 80, "end_pos": 127, "start_aa": "Arg", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { 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Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052559.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040509550", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040509550" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AA41", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA41" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "KLHL33", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA41", "locus": {} } ], "crossref": [ { "id": "A0A8V1AA41", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AA41", "database": "AlphaFoldDB", "categories": [] }, { "id": "101750992", "url": "https://www.ncbi.nlm.nih.gov/gene/101750992", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006652", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006652", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011705", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011705", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015915", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015915", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "QDTHLIH", "url": "https://omabrowser.org/oma/group/QDTHLIH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AA41", "url": "https://www.orthodb.org/?gene=A0A8V1AA41", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ACV5", "url": "https://www.orthodb.org/?gene=A0A8V1ACV5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45632", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45632", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45632:SF14", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45632:SF14", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07707", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07707", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21536", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21536", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24681", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24681", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040509550", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040509550", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AA41", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA41", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AA41-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA41-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ACV5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACV5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ACV5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACV5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVVSSLWQWIQYILPWGSANSSPVCPPRTTWLWGWHPDLTPRVPTGKMWVAEGPAPAQWHLRDGAHARHFLAMANDLRTAGQLVDVAVGPEGDVAHAVVLASVSSFFLCFLEDRTRELRRGPPAHIPLPPGATLWGWRALLTFAYEGTVPHGREREVEESARVLGAPRVVAACASRLEGDHQEGGPEALEEQWETLRAMEQLHASGLGCDLRLQAGDEVIPVQRLALSCSCDFFRALFTCPMREATHDPAAPLTTGLTPAELRLLLSFAYTGAVVGPWPAVLEAAETSLRYQAWGLLTLCLDVFTHGLTPETGLDVLAFAVAYGLAQVSRTAEDYVLATFPTVVATPAFLDLPAHLLIRLLRSDGLNVLHELEALEAASRWLKANGDGREDLTREVLSSVRFALMSGQELKKIPSVTAGVADPGLLRQLVVESLAPMAQLPCRVRSLQEVLVVCGGDKLTPNMAARKPSGNLWFAHRYLNAVGLVKHVEWRALGQFPDGPRFRHAVAVVGNTLYVLGGKRYYGVHDTLASVYRYQPMDNSWERLASMTCGRSYFAAVALEGSIYALGGSSGDLYCTDTVECYNVAADTWRRCQSLPMALCGHAACALDGALYVSGGCDEAYQCQTALLRYIPGAPATVLAPMNGQRAGHVMEEAGGQLYVAGGLCQKDGQTGYRDQLAFEVYSPKLDIWVLLSPLPHAHVVGGAAVLGGELLVLGGYSHETYRDTHLIHAYQPGARRWITRGTLPHAYTDLRVCVLTVPPALRGPTCLEDPPRSPNALSNT", "length": 781, "header": "tr|A0A8V1AA41-1|A0A8V1AA41_CHICK Isoform 1 of Kelch like family member 33 OS=Gallus gallus OX=9031 GN=KLHL33 PE=4 SV=1 CANONICAL=A0A8V1AA41-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AA41-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA41/entry#A0A8V1AA41-1", "sequence": { "sequence": "MVVSSLWQWIQYILPWGSANSSPVCPPRTTWLWGWHPDLTPRVPTGKMWVAEGPAPAQWHLRDGAHARHFLAMANDLRTAGQLVDVAVGPEGDVAHAVVLASVSSFFLCFLEDRTRELRRGPPAHIPLPPGATLWGWRALLTFAYEGTVPHGREREVEESARVLGAPRVVAACASRLEGDHQEGGPEALEEQWETLRAMEQLHASGLGCDLRLQAGDEVIPVQRLALSCSCDFFRALFTCPMREATHDPAAPLTTGLTPAELRLLLSFAYTGAVVGPWPAVLEAAETSLRYQAWGLLTLCLDVFTHGLTPETGLDVLAFAVAYGLAQVSRTAEDYVLATFPTVVATPAFLDLPAHLLIRLLRSDGLNVLHELEALEAASRWLKANGDGREDLTREVLSSVRFALMSGQELKKIPSVTAGVADPGLLRQLVVESLAPMAQLPCRVRSLQEVLVVCGGDKLTPNMAARKPSGNLWFAHRYLNAVGLVKHVEWRALGQFPDGPRFRHAVAVVGNTLYVLGGKRYYGVHDTLASVYRYQPMDNSWERLASMTCGRSYFAAVALEGSIYALGGSSGDLYCTDTVECYNVAADTWRRCQSLPMALCGHAACALDGALYVSGGCDEAYQCQTALLRYIPGAPATVLAPMNGQRAGHVMEEAGGQLYVAGGLCQKDGQTGYRDQLAFEVYSPKLDIWVLLSPLPHAHVVGGAAVLGGELLVLGGYSHETYRDTHLIHAYQPGARRWITRGTLPHAYTDLRVCVLTVPPALRGPTCLEDPPRSPNALSNT", "length": 781, "header": "tr|A0A8V1AA41-1|A0A8V1AA41_CHICK Isoform 1 of Kelch like family member 33 OS=Gallus gallus OX=9031 GN=KLHL33 PE=4 SV=1 CANONICAL=A0A8V1AA41-1" }, "locus": { "chromosome": "28", "start_pos": 1206140, "end_pos": 1202743, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067162.1", "url": "https://www.ensembl.org/id/ENSGALT00010067162.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041066.1", "url": "https://www.ensembl.org/id/ENSGALP00010041066.1" } ] } }, { "isoform_ac": "A0A8V1ACV5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA41/entry#A0A8V1ACV5-1", "sequence": { "sequence": "MSARSQHSSAGRGTRRTARDTALPRTHDTVQRKMWVAEGPAPAQWHLRDGAHARHFLAMANDLRTAGQLVDVAVGPEGDVAHAVVLASVSSFFLCFLEDRTRELRRGPPAHIPLPPGATLWGWRALLTFAYEGTVPHGREREVEESARVLGAPRVVAACASRLEGDHQEGGPEALEEQWETLRAMEQLHASGLGCDLRLQAGDEVIPVQRLALSCSCDFFRALFTCPMREATHDPAAPLTTGLTPAELRLLLSFAYTGAVVGPWPAVLEAAETSLRYQAWGLLTLCLDVFTHGLTPETGLDVLAFAVAYGLAQVSRTAEDYVLATFPTVVATPAFLDLPAHLLIRLLRSDGLNVLHELEALEAASRWLKANGDGREDLTREVLSSVRFALMSGQELKKIPSVTAGVADPGLLRQLVVESLAPMAQLPCRVRSLQEVLVVCGGDKLTPNMAARKPSGNLWFAHRYLNAVGLVKHVEWRALGQFPDGPRFRHAVAVVGNTLYVLGGKRYYGVHDTLASVYRYQPMDNSWERLASMTCGRSYFAAVALEGSIYALGGSSGDLYCTDTVECYNVAADTWRRCQSLPMALCGHAACALDGALYVSGGCDEAYQCQTALLRYIPGAPATVLAPMNGQRAGHVMEEAGGQLYVAGGLCQKDGQTGYRDQLAFEVYSPKLDIWVLLSPLPHAHVVGGAAVLGGELLVLGGYSHETYRDTHLIHAYQPGARRWITRGTLPHAYTDLRVCVLTVPPALRGPTCLEDPPRSPNALSNT", "length": 767, "header": "tr|A0A8V1ACV5-1|A0A8V1ACV5_CHICK Computationally mapped isoform of Kelch like family member 33 OS=Gallus gallus OX=9031 GN=KLHL33 PE=4 SV=1 CANONICAL=A0A8V1AA41-1" }, "locus": { "chromosome": "28", "start_pos": 1206681, "end_pos": 1202743, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067164.1", "url": "https://www.ensembl.org/id/ENSGALT00010067164.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041068.1", "url": "https://www.ensembl.org/id/ENSGALP00010041068.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A140LGZ3-1", "protein_name": "Kelch-like protein 33", "gene_name": "si:ch211-63p21.8", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEFTRKYLPLEWEERWRREKERRKRMMEEGGEKFEEEEKRRLKWIVSYNDGRMGMKEKDNEHGNAEEDEPMHRYRRQSYASEIHQTLLEMKMADVLTDLTLSTEDGMSVRVHWLVLAAVSSIIQEKDEDVKEISLSPEVCRSGLVAVVEFAYTGGISNLNIDNMMQIQTAAESLGAPRVLELLKKENKGDEVRKSLAEEQMTVGLQCMKDFWDKRLRCDVKLIAEGTVFHAHRALLSASSEYFRGMFTRGMKESREESVSLLSAGAAELEILLKCCYSGALELSWSCVFELTCTSLQFQFQPAVSLCLQFLQQEMDVHNCLDVASFAEAYGMVDIMEMAEDFVLRHFQEISATPKFQDLPADKLLQFLRCDALSVPSELAVFRAVVSWIETDPAERLLQAEQLMKAVRFPFMTFREFQEVRAVNLTMECSGEYDVELYKSALKEFGVSDHVAQQRVRYPKDALVLVGGDELDADNGRRRPSKQLWFVNSLRSGTGLVKQMEWRLLGEMPDQARFRHGVGVLNGQLYIAGGCYFYSKADIMKSVYRYDPVREQWEKLSDLLELRSNFTLVVNGENLYAVGGDKEINTNLDSVEKYSPETNSWSFTHPLDQALSGHAATVCGGEIFISGGFNCKYECLVSMSAYHPLRGTTYLSDMIHDRAQHCMESLRNRIYVAGGVCNLRKFYTNQLSCEVYDLVHDVWTEFTALPVPHVGAASAVLEERLYILGGYCQEDYSEARLAHRYDPVTHRWDSMGKIPGPVTDIRTCLLKLPEHIRK", "length": 774 }, "evidence": [ { "id": "A0A8V1AA41", "url": "https://omabrowser.org/oma/group/A0A8V1AA41/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A6NCF5-1", "protein_name": "Kelch-like protein 33", "gene_name": "KLHL33", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLLSGMRESQGTEVSLRTISTQDLRLLVSFAYSGVVRARWPGLLRAAQAALQYQSSSCLDLCQKGLARGLSPARCLALFPMAEAPGLERLWSKARHYLLTHLPAVALCPAFPSLPAACLAELLDSDELHVQEEFEAFVAARCWLAANPETQESEAKALLRCVRFGRMSTRELRRVRAAGLLPPLTPDLLHQLMVEADVPGQERRREPDRALVVIGGDGLRPDMALRQPSRAVWWARAFRCGVGLVRTVEWGQLPALPAPGRFRHGAASLAGSELYVCGGQDFYSHSNTLASTLRWEPSQEDWEEMAPLSQARSLFSLVALDGKLYALGGRHNDVALDSVETYNPELNVWRPAPALPAPCFAHAAAILEGQLYVSGGCGGTGQYLASLMHYDPKLEKPGTFLSPMGVPRAGHVMAALGGRLYVAGGLGETEDLLSFEAYELRTDSWTHLAPLPSPHVGAASAVLQGELLVLGGYSHRTYALSHLIHAYCPGLGRWLCLGTLPRPRAEMPACILTLPAVQHIALVPTPHQTKPAG", "length": 533 }, "evidence": [ { "id": "A0A8V1AA41", "url": "https://omabrowser.org/oma/group/A0A8V1AA41/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "F1M601-1", "protein_name": "Kelch-like family member 33", "gene_name": "Klhl33", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTSLSSDLEHVSLPIQKDNLESPVPARRTSSRSPSSDEDPGLLSFSLAERNPPSPLVSGNLPFPASAPEKGKKQDDSEDSAEPEMLCSVEHPCQFFAEAQRLREQKLLLDEEVTVRGQVYGVHRVILAAISRLFRGRLLEGGGQQPGFSLDVTPRGWEAALTFAYEGVLGPAPQDEVLAAAKALGAPRVKIAAQLRPEGLGKAREDEKKLTQAEELRENLHSIERLYREGIGCDLELEAEGYRLQVHRVALACGSEFFGAMLLSGMRESQGTKVSLRTISSQDLRLLVSFAYTGVVRERWPGLLRAAQAALQYQSSSCLDLCQRALAQSLCPALCLALFPMIEAPGLEKVWKKAHHYLLTHLPAVASCPAFPSLPVTCLAELLDSDELHVQEEFEAFAAARCWLAANPETQESEAKALLRCVRFGRMSTRELRKVRAAGLPEPLQPDLLYQLMVEAEVPGQERWREPDQALVVIGGDGLRPDMDRRKPSCKVWWARAFHCGMGLVRTVEWCRLPNLPAPGRFRHGAASLTGGELYVCGGQDFYSPTNTLASTLRWSSSQEDWEEMAPLCQARSFFPLVVFDGQLYVLGGRDNGVALNSVETYNPELNVWRPAPALPAPCFAHAAAILEDRLYVSGGCSGTGQYLDSLIHYDPKLKKPGTLLSPMGVARASHVMAALGGKLYVAGGIGDTGDLLSFEAYEPKTDSWTHLASLPSPHVGAAGAVLQGELLVLGGYSHRTYAISHLVHAYCPGLDRWLCLGTLPRPRAEMPACVLTLSSVQHRALVPTQHQNKPAG", "length": 793 }, "evidence": [ { "id": "A0A8V1AA41", "url": "https://omabrowser.org/oma/group/A0A8V1AA41/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1MIH3-1", "protein_name": "Kelch like family member 33", "gene_name": "KLHL33", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSLSDSTRRPSGAEEVSLLVQKDDLDLPLPTQRTPSWPPSPDEDPGLPPFPLEEPGPRPMTPASLPSPALSLEEEEEEEDEEDGEDSAEPEGLCSEEHPSQFFAEAQRLREQRLLLDEEVSVGGRAYGVHRVILASVSSLFRGRLLGSRGPQPPLSLDVTPAAWEAVLTFAYEGVLGPASREDVLVAAEALGAPRIKAAAQWGRQGTGSGREDEKQPSQAEELRENLRSIELLYQEGIGCDLELEAGGCRLRVHRAALACGSEFFGAMLLSGMRESQGTEVSLHTISAQDLRLLVSFAYSGVVRAKWPGLLRAAQAALQYQSSSCLALCQKALARGLSPARCLALIPMAEAPGLERLWSKARHYLLTHLPAVALCSTFPTLPAACLAELLDSDELHLQEEFEAFVAARRWLAANPDTQESEAKALLRCVRFGRMSTRELRRVRAAGLPPPLSPDLLHQLMVEAEVPGQERRREPDQALVVIGGDGLRSDMATRQPSRGVWWARAFRCGIGLVRTVEWGRLPALPAPGRFRHGAASLAGSVLYVCGGQDFYSHSNTLASTLRWDPSQEDWEEMAPLCQPRSLFPLVALDGLLYALGGRDSGIALRSVETYNPELNVWRPAPPLPAPRFAHAAAVLEGQLYVSGGCSETGQYQASLLHYDPKLEKPVTLLSPMGVPRAGHVMASLGGRLYVAGGLGQTGDLLSFEAYDPSTGSWTQLTPLPSPHVGAAGAVLQGELLVLGGYSHRTYAPSHLIHAYCPGLGRWLCLGTLPRPRAEMPACILTLPAVQHVALVPTRHQTKPAG", "length": 800 }, "evidence": [ { "id": "A0A8V1AA41", "url": "https://omabrowser.org/oma/group/A0A8V1AA41/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3UW92-1", "protein_name": "Kelch-like 33", "gene_name": "Klhl33", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLLSGMRESQGTKVTLRTISSQDLRLLVSFAYTGVVRERWPGLLRAAQAALQYQSSSCLDLCQKALAQSLCPALCLALFPMIEAPGLEKVWGKAHDYLLSHLPAVASCPTFSSLPVTCLAELLDSDELHVQEEFEAFSAARCWLAANPETHESEAKALLRCVRFGRMSTRELRKVRAAGLPPSLPPDLLYQLMVEAEVPGQERWREPDQALVVIGGDGLRPDMDRRQPSCKVWWARAFHCGMGLVRTVEWCRLPNLPAPGRFRHGAASLTGSELYVCGGQDFYSHNSTLASTLRWSSSQEDWEEMAPLCQARSFFPLVVFDGQLYALGGRDNGVALNSVETYNPELNVWRPAPALPAPCFAHAAAILEDRLYVSGGCSGTGQYLDSLIHYDPKLKRPGTLLSPMGVARASHVMAALGGKLYVAGGVGDTGDLLSFEAYEPKSDSWTQLASLPSPHVGAAGAVLQGELLVLGGYSHRTYAISHLVHAYCPGLDRWLCLGTLPRPRAEMPACILTLPSVQHIALVPTQHQNKPAG", "length": 533 }, "evidence": [ { "id": "A0A8V1AA41", "url": "https://omabrowser.org/oma/group/A0A8V1AA41/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 20, "end_pos": 22, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AA41", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA41" }, { "id": "PS50097", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50097" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BTB", "eco_id": "ECO_0000259", "start_pos": 209, "end_pos": 274, "start_aa": "Cys", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 20, "end_pos": 22 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", 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"table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AA44-1", "uniprot_ac": "A0A8V1AA44", "uniprot_id": "A0A8V1AA44_CHICK", "mass": { "chemical_mass": 17788.0, "monoisotopic_mass": 17788.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Keratin", "type": "recommended", "evidence": [ { "id": "A0A8V1AA44", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA44/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AA44", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA44" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA44", "locus": {} } ], "crossref": [ { "id": "A0A8V1AA44", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AA44", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR003461", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003461", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR31203", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31203", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31203:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31203:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02422", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02422", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1AA44", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA44", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AA44-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA44-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMNISSECLPTCEVACTQPYAYSRSLEPCVTSCGDSRAVVYPPPVVLTFPGPTLASCSQESIVGTSIPQPYGPAIQYGSEESYGMGGSVGTSGNGVSFGDGGVSGMGGYFGSQGSVGYGGMSGMGGSAWCGGVSGMGGSFGKGGSFGFGGSSRIGSCYSKQSYRSHRGSRFGIYSSF", "length": 177, "header": "tr|A0A8V1AA44-1|A0A8V1AA44_CHICK Isoform 1 of Keratin OS=Gallus gallus OX=9031 GN= PE=3 SV=1 CANONICAL=A0A8V1AA44-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AA44-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA44/entry#A0A8V1AA44-1", "sequence": { "sequence": "MMNISSECLPTCEVACTQPYAYSRSLEPCVTSCGDSRAVVYPPPVVLTFPGPTLASCSQESIVGTSIPQPYGPAIQYGSEESYGMGGSVGTSGNGVSFGDGGVSGMGGYFGSQGSVGYGGMSGMGGSAWCGGVSGMGGSFGKGGSFGFGGSSRIGSCYSKQSYRSHRGSRFGIYSSF", "length": 177, "header": "tr|A0A8V1AA44-1|A0A8V1AA44_CHICK Isoform 1 of Keratin OS=Gallus gallus OX=9031 GN= PE=3 SV=1 CANONICAL=A0A8V1AA44-1" }, "locus": { "chromosome": "25", "start_pos": 1358598, "end_pos": 1358068, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069581.1", "url": "https://www.ensembl.org/id/ENSGALT00010069581.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042842.1", "url": "https://www.ensembl.org/id/ENSGALP00010042842.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "structural constituent of cytoskeleton", "id": "GO:0005200", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005200", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AA44", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA44" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "intermediate filament", "id": "GO:0005882", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005882", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AA44", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA44" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 3, "end_pos": 5, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 3, "end_pos": 5 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": 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"n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AA56-1", "uniprot_ac": "A0A8V1AA56", "uniprot_id": "A0A8V1AA56_CHICK", "mass": { "chemical_mass": 27942.0, "monoisotopic_mass": 27942.0 }, "refseq": { "ac": "XP_015154259", "name": "synaptophysin-like protein 2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015154259" }, "gene_names": [ { "name": "SYPL2", "type": "recommended", "evidence": [ { "id": "A0A8V1AA56", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA56" } ] }, { "name": "SYPL2", "type": "synonym", "evidence": [ { "id": "XP_015154259", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015154259" } ] } ], "protein_names": [ { "name": "Synaptophysin like 2", "type": "synonym", "evidence": [ { "id": "A0A8V1AA56", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA56/entry#names_and_taxonomy" } ] }, { "name": "synaptophysin-like protein 2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015154259", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015154259" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052557.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015154259.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015154259", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015154259" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AA56", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA56" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SYPL2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA56", "locus": { "chromosome": "26", "start_pos": 1261584, "end_pos": 1257681, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027714", "url": "https://www.ensembl.org/id/ENSGALG00010027714" } ] } } ], "crossref": [ { "id": "A0A8V1AA56", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AA56", "database": "AlphaFoldDB", "categories": [] }, { "id": "100858920", "url": "https://www.ncbi.nlm.nih.gov/gene/100858920", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001285", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001285", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008253", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008253", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:100858920", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100858920", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VFYLRFH", "url": "https://omabrowser.org/oma/group/VFYLRFH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AA56", "url": "https://www.orthodb.org/?gene=A0A8V1AA56", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ACX4", "url": "https://www.orthodb.org/?gene=A0A8V1ACX4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AHG0", "url": "https://www.orthodb.org/?gene=A0A8V1AHG0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10306", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10306", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10306:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10306:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01284", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01284", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015154259", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015154259", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AA56", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA56", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AA56-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA56-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ACX4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACX4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ACX4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACX4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHG0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHG0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHG0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHG0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAESGAPSGGDKAPRLQDRVLAGMRWGRLQEPLGFVKVLEWLFAIFAFGACGSFSGESGATVKCSGETKEMSAISVQFGYPFRLYQIPFEMPECDGESEPRTLHLVGDFSAPAEFFVTLGVFSFLYAMAALVLYLRFHSLYADNKKLPFTDFCVTVCFAFFWLVAAAAWGKGLSDVKAATRPSSLIAAMSVCQGHDVVCNAGATPAMGLANISVLFGFINFLLWAGNCWFVFKETTWHTQAEPRGDSAAEQGAIDKQ", "length": 257, "header": "tr|A0A8V1AA56-1|A0A8V1AA56_CHICK Isoform 1 of Synaptophysin like 2 OS=Gallus gallus OX=9031 GN=SYPL2 PE=3 SV=1 CANONICAL=A0A8V1AA56-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AA56-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA56/entry#A0A8V1AA56-1", "sequence": { "sequence": "MAESGAPSGGDKAPRLQDRVLAGMRWGRLQEPLGFVKVLEWLFAIFAFGACGSFSGESGATVKCSGETKEMSAISVQFGYPFRLYQIPFEMPECDGESEPRTLHLVGDFSAPAEFFVTLGVFSFLYAMAALVLYLRFHSLYADNKKLPFTDFCVTVCFAFFWLVAAAAWGKGLSDVKAATRPSSLIAAMSVCQGHDVVCNAGATPAMGLANISVLFGFINFLLWAGNCWFVFKETTWHTQAEPRGDSAAEQGAIDKQ", "length": 257, "header": "tr|A0A8V1AA56-1|A0A8V1AA56_CHICK Isoform 1 of Synaptophysin like 2 OS=Gallus gallus OX=9031 GN=SYPL2 PE=3 SV=1 CANONICAL=A0A8V1AA56-1" }, "locus": { "chromosome": "26", "start_pos": 1261568, "end_pos": 1258271, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067177.1", "url": "https://www.ensembl.org/id/ENSGALT00010067177.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041081.1", "url": "https://www.ensembl.org/id/ENSGALP00010041081.1" } ] } }, { "isoform_ac": "A0A8V1ACX4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA56/entry#A0A8V1ACX4-1", "sequence": { "sequence": "MEGRTEVPDRVLAGMRWGRLQEPLGFVKVLEWLFAIFAFGACGSFSGESGATVKCSGETKEMSAISVQFGYPFRLYQIPFEMPECDGESEPRTLHLVGDFSAPAEFFVTLGVFSFLYAMAALVLYLRFHSLYADNKKLPFTDFCVTVCFAFFWLVAAAAWGKGLSDVKAATRPSSLIAAMSVCQGHDVVCNAGATPAMGLANISVLFGFINFLLWAGNCWFVFKETTWHTQAEPRGDSAAEQGAIDKQ", "length": 248, "header": "tr|A0A8V1ACX4-1|A0A8V1ACX4_CHICK Computationally mapped isoform of Synaptophysin like 2 OS=Gallus gallus OX=9031 GN=SYPL2 PE=3 SV=1 CANONICAL=A0A8V1AA56-1" }, "locus": { "chromosome": "26", "start_pos": 1261568, "end_pos": 1257998, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067179.1", "url": "https://www.ensembl.org/id/ENSGALT00010067179.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041083.1", "url": "https://www.ensembl.org/id/ENSGALP00010041083.1" } ] } }, { "isoform_ac": "A0A8V1AHG0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA56/entry#A0A8V1AHG0-1", "sequence": { "sequence": "MAPGLGFRAAGRAALQRHRTGRGKLRHEWDQSVGLFAIFAFGACGSFSGESGATVKCSGETKEMSAISVQFGYPFRLYQIPFEMPECDGESEPRTLHLVGDFSAPAEFFVTLGVFSFLYAMAALVLYLRFHSLYADNKKLPFTDFCVTVCFAFFWLVAAAAWGKGLSDVKAATRPSSLIAAMSVCQGHDVVCNAGATPAMGLANISVLFGFINFLLWAGNCWFVFKETTWHTQAEPRGDSAAEQGAIDKQ", "length": 250, "header": "tr|A0A8V1AHG0-1|A0A8V1AA56_CHICK Computationally mapped isoform of Synaptophysin like 2 OS=Gallus gallus OX=9031 GN=SYPL2 PE=3 SV=1 CANONICAL=A0A8V1AA56-1" }, "locus": { "chromosome": "26", "start_pos": 1261568, "end_pos": 1258916, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067176.1", "url": "https://www.ensembl.org/id/ENSGALT00010067176.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041080.1", "url": "https://www.ensembl.org/id/ENSGALP00010041080.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 204, "start_aa": "Thr", "end_pos": 204, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr204", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:100858920", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100858920", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A5G2R2H0-1", "protein_name": "Synaptophysin like 2", "gene_name": "SYPL2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSSTESSSRTEDKSPRQQVDRLLVGLRWQRLEEPLGFIKVLQWLFAIFAFGCCGSYSGETGATVRCNNEAKDVSAIIVLFGYPFRLNRVQYEMPLCDDESTSKTMHLMGDFSAPAEFFVTLGIFSFFYTIAALVLYLRFHSLYTENRRFPLVDFCVTVSFTFFWLVAAAAWGKGLTDVKGATRPSSLTAAMSVCHGEEAVCSGGATPSMGLANISVLFGFINFFLWAGNCWFVFKETPWYGQGQDQGQGTSQESAAEQGAVEKQ", "length": 264 }, "evidence": [ { "id": "A0A8V1AA56", "url": "https://omabrowser.org/oma/group/A0A8V1AA56/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "D4A6M0-1", "protein_name": "Synaptophysin-like 2", "gene_name": "Sypl2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSTESPGRTSDKSPRQQVDRLLLGLRWQRLEEPLGFIKVLQWLFAIFAFGSCGSYSGETGALVRCNNDPKDVSSIIVLFGYPFRLYQVQYEMPLCDEESTSKTMNLMGDFSAPAEFFVTLGIFSFFYTMAALVIYLRFHKVYTENKRFPLVDFCVTVSFTFFWLVAAAAWGKGLTDVKGATRPSSLTAAMSVCHGEEAVCSAGATPSMGLANISVLFGFINFFLWAGNCWFVFKETPWHGQGQDQGQGPSQESAAEQGAVEKQ", "length": 264 }, "evidence": [ { "id": "A0A8V1AA56", "url": "https://omabrowser.org/oma/group/A0A8V1AA56/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O89104-1", "protein_name": "Synaptophysin-like protein 2", "gene_name": "Sypl2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSTESPGRTSDKSPRQQVDRLLLGLRWQRLEEPLGFIKVLQWLFAIFAFGSCGSYSGETGALVLCNNEAKDVSSIIVLFGYPFRLYQVQYEMPLCDQDSTSKTMNLMGDFSAPAEFFVTLGIFSFFYTMAALVIYLRFHKLYTENKRFPLVDFCVTVSFTFFWLVAAAAWGKGLTDVKGATRPSSLTAAMSVCHGEEAVCSAGATPSMGLANLSVLFGFINFFLWAGNCWFVFKETPWHGQGQDQGQGPSQESAAEQGAVEKQ", "length": 264 }, "evidence": [ { "id": "A0A8V1AA56", "url": "https://omabrowser.org/oma/group/A0A8V1AA56/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5VXT5-1", "protein_name": "Synaptophysin-like protein 2", "gene_name": "SYPL2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSSTESAGRTADKSPRQQVDRLLVGLRWRRLEEPLGFIKVLQWLFAIFAFGSCGSYSGETGAMVRCNNEAKDVSSIIVAFGYPFRLHRIQYEMPLCDEESSSKTMHLMGDFSAPAEFFVTLGIFSFFYTMAALVIYLRFHNLYTENKRFPLVDFCVTVSFTFFWLVAAAAWGKGLTDVKGATRPSSLTAAMSVCHGEEAVCSAGATPSMGLANISVLFGFINFFLWAGNCWFVFKETPWHGQGQGQDQDQDQDQGQGPSQESAAEQGAVEKQ", "length": 272 }, "evidence": [ { "id": "A0A8V1AA56", "url": "https://omabrowser.org/oma/group/A0A8V1AA56/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "synaptic vesicle membrane", "id": "GO:0030672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030672", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AA56", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA56" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AA56", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA56" } ], "pmid": "" }, { "name": "synaptic vesicle", "id": "GO:0008021", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008021", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AA56", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA56" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 211, "end_pos": 213, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AA56", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA56" }, { "id": "PS51225", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51225" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "MARVEL", "eco_id": "ECO_0000259", "start_pos": 28, "end_pos": 236, "start_aa": "Arg", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 204 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 211, "end_pos": 213 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AA61-1", "uniprot_ac": "A0A8V1AA61", "uniprot_id": "A0A8V1AA61_CHICK", "mass": { "chemical_mass": 76349.0, "monoisotopic_mass": 76349.0 }, "refseq": { "ac": "XP_040508823", "name": "ataxin-7-like protein 2 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040508823" }, "gene_names": [ { "name": "ATXN7L2", "type": "recommended", "evidence": [ { "id": "A0A8V1AA61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA61" } ] }, { "name": "ATXN7L2", "type": "synonym", "evidence": [ { "id": "XP_040508823", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040508823" } ] } ], "protein_names": [ { "name": "Ataxin 7 like 2", "type": "synonym", "evidence": [ { "id": "A0A8V1AA61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA61/entry#names_and_taxonomy" } ] }, { "name": "ataxin-7-like protein 2 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_040508823", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040508823" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052557.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040508823", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040508823" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AA61", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA61" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ATXN7L2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA61", "locus": { "chromosome": "26", "start_pos": 1268077, "end_pos": 1262374, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027717", "url": "https://www.ensembl.org/id/ENSGALG00010027717" } ] } } ], "crossref": [ { "id": "A0A8V1AA61", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AA61", "database": "AlphaFoldDB", "categories": [] }, { "id": "429691", "url": "https://www.ncbi.nlm.nih.gov/gene/429691", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013243", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013243", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052237", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052237", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "GKTPMAP", "url": "https://omabrowser.org/oma/group/GKTPMAP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AA61", "url": "https://www.orthodb.org/?gene=A0A8V1AA61", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AHG6", "url": "https://www.orthodb.org/?gene=A0A8V1AHG6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15117", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15117", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15117:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15117:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08313", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08313", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040508823", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040508823", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AA61", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA61", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AA61-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA61-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHG6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHG6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHG6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHG6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAARGRAAAMAAAERRLPSVDEFAGQSWSAWVERAGPPAEPAGLELEESSKGSKKLDAMTLIKEDMSIFGHCPAHDEFYLVVCNHCSQVVKPQAFQKHCERRHGPLSKLYSKCHAVNGQPAGKALRDKGARSRAQPLPEKAQKDNNLCLFMPVVNLEKIPSFPKPEGLKAAPKTPPKAPPAPPASSPAEPPGRPSPAPPPPPKEPPGAGGDSVPAPTASPVLKAGEKEPGVCRPPPRAHKKLTRKECDLNRQCGVLNPDTKKVCTRLLTCKIHSVHQRREVQGRAKDFDVLVAELKASSRREAPKEKSPPRKDPPGIEPPAPPALPQPPAAPPGASPCRPRPPHAHCPPPRARLSSDSDPEEGDGGLFPFPLPKEGGSRGSSEDSEEEGAADDAHRPDCHYAARPPRPQAFCTFGSRLVSPGCYVFNRRLDRFCSALGSMLERHLSSHMWRKIPPAADSQLPAAPAPPSPAGPAAPTPPPHARTPPTPTGPRDGRVPAGINYTVGSPHAAAACSQPECGGGGSQSITSPLPANIPSPSFSKLPSTKASKSSRAKEAAGGTEPDSVARKRKQPLGAAASPPYKRTCPGDGPKSKSPACQVSAPPGKTKSPAVAALNGSACAGSRLKRALPPDCRPPLSAAPEPRGSPLRGVGVPPPPPRCISEDEVKKRKNSATYCRPSKPKHAAPPPAPPPAPSPAPPDLGCSVRRKKPGSALGFEEKRSVLKSKAH", "length": 727, "header": "tr|A0A8V1AA61-1|A0A8V1AA61_CHICK Isoform 1 of Ataxin 7 like 2 OS=Gallus gallus OX=9031 GN=ATXN7L2 PE=4 SV=1 CANONICAL=A0A8V1AA61-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AA61-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA61/entry#A0A8V1AA61-1", "sequence": { "sequence": "MAARGRAAAMAAAERRLPSVDEFAGQSWSAWVERAGPPAEPAGLELEESSKGSKKLDAMTLIKEDMSIFGHCPAHDEFYLVVCNHCSQVVKPQAFQKHCERRHGPLSKLYSKCHAVNGQPAGKALRDKGARSRAQPLPEKAQKDNNLCLFMPVVNLEKIPSFPKPEGLKAAPKTPPKAPPAPPASSPAEPPGRPSPAPPPPPKEPPGAGGDSVPAPTASPVLKAGEKEPGVCRPPPRAHKKLTRKECDLNRQCGVLNPDTKKVCTRLLTCKIHSVHQRREVQGRAKDFDVLVAELKASSRREAPKEKSPPRKDPPGIEPPAPPALPQPPAAPPGASPCRPRPPHAHCPPPRARLSSDSDPEEGDGGLFPFPLPKEGGSRGSSEDSEEEGAADDAHRPDCHYAARPPRPQAFCTFGSRLVSPGCYVFNRRLDRFCSALGSMLERHLSSHMWRKIPPAADSQLPAAPAPPSPAGPAAPTPPPHARTPPTPTGPRDGRVPAGINYTVGSPHAAAACSQPECGGGGSQSITSPLPANIPSPSFSKLPSTKASKSSRAKEAAGGTEPDSVARKRKQPLGAAASPPYKRTCPGDGPKSKSPACQVSAPPGKTKSPAVAALNGSACAGSRLKRALPPDCRPPLSAAPEPRGSPLRGVGVPPPPPRCISEDEVKKRKNSATYCRPSKPKHAAPPPAPPPAPSPAPPDLGCSVRRKKPGSALGFEEKRSVLKSKAH", "length": 727, "header": "tr|A0A8V1AA61-1|A0A8V1AA61_CHICK Isoform 1 of Ataxin 7 like 2 OS=Gallus gallus OX=9031 GN=ATXN7L2 PE=4 SV=1 CANONICAL=A0A8V1AA61-1" }, "locus": { "chromosome": "26", "start_pos": 1267624, "end_pos": 1262410, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067182.1", "url": "https://www.ensembl.org/id/ENSGALT00010067182.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041086.1", "url": "https://www.ensembl.org/id/ENSGALP00010041086.1" } ] } }, { "isoform_ac": "A0A8V1AHG6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA61/entry#A0A8V1AHG6-1", "sequence": { "sequence": "MTLIKEDMSIFGHCPAHDEFYLVVCNHCSQVVKPQAFQKHCERRHGPLSKLYSKCHAVNGQPAGKALRDKGARSRAQPLPEKAQKDNNLCLFMPVVNLEKIPSFPKPEGLKAAPKTPPKAPPAPPASSPAEPPGRPSPAPPPPPKEPPGAGGDSVPAPTASPVLKAGEKEPGVCRPPPRAHKKLTRKECDLNRQCGVLNPDTKKVCTRLLTCKIHSVHQRREVQGRAKDFDVLVAELKASSRREAPKEKSPPRKDPPGIEPPAPPALPQPPAAPPGASPCRPRPPHAHCPPPRARLSSDSDPEEGDGGLFPFPLPKEGGSRGSSEDSEEEGAADDAHRPDCHYAARPPRPQAFCTFGSRLVSPGCYVFNRRLDRFCSALGSMLERHLSSHMWRKIPPAADSQLPAAPAPPSPAGPAAPTPPPHARTPPTPTGPRDGRVPAGINYTVGSPHAAAACSQPECGGGGSQSITSPLPANIPSPSFSKLPSTKASKSSRAKEAAGGTEPDSVARKRKQPLGAAASPPYKRTCPGDGPKSKSPACQVSAPPGKTKSPAVAALNGSACAGSRLKRALPPDCRPPLSAAPEPRGSPLRGVGVPPPPPRCISEDEVKKRKNSATYCRPSKPKHAAPPPAPPPAPSPAPPDLGCSVRRKKPGSALGFEEKRSVLKSKAH", "length": 669, "header": "tr|A0A8V1AHG6-1|A0A8V1AA61_CHICK Computationally mapped isoform of Ataxin 7 like 2 OS=Gallus gallus OX=9031 GN=ATXN7L2 PE=4 SV=1 CANONICAL=A0A8V1AA61-1" }, "locus": { "chromosome": "26", "start_pos": 1267624, "end_pos": 1263689, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067181.1", "url": "https://www.ensembl.org/id/ENSGALT00010067181.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041085.1", "url": "https://www.ensembl.org/id/ENSGALP00010041085.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 217, "start_aa": "Thr", "end_pos": 217, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr217", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 477, "start_aa": "Thr", "end_pos": 477, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr477", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A9J7JBE3-1", "protein_name": "Ataxin-7-like protein 2 isoform X2", "gene_name": "Atxn7l2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAVRERAVAAMAALERRVPSLDDFAGQSWSSWVERADLPAADGAELEESNKNVKKLDAMTLIKEDMSIFGHCPAHDDFYLVVCNHCSQVVKPQAFQKHCERRHGPLSKLYARAPPPPPAPASSQKCHVVNGQGPACRAPGSTKTSSREKGQGSRSRGHQPPEKTQKDNLCLFVPVVNLEKMSSLPKPDGHGVRVAPPSAFLSQPGGLPKDSPGKVPTAPSPKEPPGRENMELIPGEGSSHRAESSPPEKEPSGARLPPKTHRKMARKEFDLNRQCGVINPETKKICTRLLTCKIHSVHQRREVPGRTKDFDVLVAELKASSRKGESPKEKSPGRKEPALERPSQEPPSAIQGVAAAAAPNNTSARSKQAYPYCVLPRSQASSESEADDEGPCGGDGDPGLFPFPLPRGGAQASSEESEEEGTPDDLHLPPDCHYTTRPPRPQAFCTFGSRLVSPGCYVFSRRLDRFCSALSSMLERHLSSHMWKKIPPAAEPPSHLVSPSLSDPLSPSSMGSCPRLPGPPPRPACPASIPPMKDSLVPSYPAGSPSVAAACSQAECMGGSQAITSPLPANTPSPSFSKLPPSKASKSSKGKEGVEMEAPSRKRKLSPGPTTFKRTCILEPAGKGKPSGCRGLSAKTKTTLSMGLNGTVGPRVKRAGPLDCRGSPHSSPIPVKASQLENRGMAGHPAKVLPSNCLSEEEVAKKRKNLATYCRPVKAKHCQAGVPPDGTCSVRRKKPGPALPFEEKCSTLKSKAH", "length": 753 }, "evidence": [ { "id": "A0A8V1AA61", "url": "https://omabrowser.org/oma/group/A0A8V1AA61/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0ABK0LP53-1", "protein_name": "Ataxin 7-like 2", "gene_name": "Atxn7l2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAILSVQDLRRAELEESSKNTKKLDAMTLIKEDMSIFGHCPAHDDFYLVVCNHCSQVVKPQAFQKHCERRHGPLSKLYARAPPPPPAPASSQKCHVVNGQGPACRAPGSTKTSSREKGQGSRSRGHQPPEKTQKDSLCLFVPVVNLEKMSSLPKPDGHGIRVAPPSAFLSQPGGLPKDSPGKVPTAPSPKEPPGRENMELIPGEGTSHRAEGSPPEKEPSGARLPPKTHRKMARKEFDLNRQCGVINPETKKICTRLLTCKIHSVHQRREVPGRAKDFDVLVAELKASSRKGESPKEKSPARKEPALERPSQEPPTAVQGAAAVAAPNNTFSSLSKQTYPYCTLPRSRASSESEVDDEGLCGGDGDPGLFPFPLPRGGAQASSEESEEEGTSDDLHLSPDCHYATRPPRPQAFCTFGSRLVSPGCYVFSRRLDRFCSALSSMLERHLSSHMWKKIPPAAEPPSHLVSPSLSDPLSPSSMGSCPRLPGPPPRPACPASVPPIKDSLVPSYPAGSPSVAAACSQAECMGGSQAITSPLPANTPSPSFSKLPPSKASKSSKGKEGVEMEAPSRKRKLSPGPTTFKRTCILEPAGKGKPSSCRGLSTKTKTALNLGLNGTVGPRMKRAGPLDCRGSPHSSPIPVKASQLENRGVAGHPTKVLPTNCLSEEEVAKKRKNLATYCRPVKAKHCQAGVPPDGTCSVRRKKPGPALPFEEKCSTLKVPVQLPEEHGQRGFGRG", "length": 735 }, "evidence": [ { "id": "A0A8V1AA61", "url": "https://omabrowser.org/oma/group/A0A8V1AA61/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1S5Z9-1", "protein_name": "Ataxin 7 like 2", "gene_name": "ATXN7L2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAVRERAAAAMAALERRVPSLDDFAGQSWSSWVERAELPAADGAELEESNKNMKKLDAMTLIKEDMSIFGHCPAHDDFYLVVCNHCSQVVKPQAFQKHCERRHGPLSKLYARAPPPPPAPASSQKCHVVNGQGPAYRASGSTKTSSREKGQGSRSRGHQPPEKTQKDNLCLFVPVVNLEKMSSLPKPDGHGIRVAPPSAFLSQPGSLAKDSPGKNPMAPPSKEPPGREGIEITPSEGLSHRAEGSPPEKEPGGTRLPPKTHRKMARKECDLNRQCGVVNPETKKICTRLLTCKIHSVHQRREVQGRAKDFDVLVAELKASSRKGESPKEKSPGRKEPALERPSQEPPSSVQAVAAAAAPGSTFSARAKQTYPYCALPRSRASSESELDAEGPGGGDGDPGLFPFPLPRGGAQASSEESEEEGTSDDLRLPTDCHYASRPPRPQAFCTFGSRLVSPGCYVFSRRLDRFCSALSSMLERHLSSHMWKKIPPAAEPPSHLVSSPPAAPLSPSSASSCPRLPGPPPRPACPASMPPAKDSLVPSYPAGSPSVAAACSQAECMGGSQAITSPLPANTPSPSFCKLPPSKASKSSKGKDALEVEAPSRKRKLSPGPTTFKRTCILEPTGKGKPPGCRGLSAKTKTALGVGLNGTVGPRVKRAGPLDCRGPPHPPPTPVKASQLDSQGGAGLTAKALPTSCLSEEEVAKKRKNLATYCRPVKAKHCQAGAPADAACSVRRKKPGPALAFEDKCSPLKSKAH", "length": 754 }, "evidence": [ { "id": "A0A8V1AA61", "url": "https://omabrowser.org/oma/group/A0A8V1AA61/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q5T6C5-1", "protein_name": "Ataxin-7-like protein 2", "gene_name": "ATXN7L2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAVRERAAAAMAALERRVPSLDDFAGQSWSSWVERADLPAADGAELEESSKNTKKLDAMTLIKEDMSIFGHCPAHDDFYLVVCNHCSQVVKPQAFQKHCERRHGPLSKLYGRAPPPPPAPASSQKCHVVNGQGPACRAPGSTKTSSREKGQGSRSRGHQPPEKTQKDNLCQPGGLTKDSPGKPPMAPPSKEPPGRENIEIIPSEGSSHWAEGSPPEKEPSGTRLPPKTHRKMARKECDLNRQCGVINPETKKICTRLLTCKIHSVHQRREVQGRAKDFDVLVAELKANSRKGESPKEKSPGRKEQVLERPSQELPSSVQVVAAVAAPSSTFSVRAKQTYPYCALPRSRASSESELDDEGPCGGDGDPGLFPFPMPRGGTQASSEESEEEGTSDDLHPPPDCHYATRPPRPQAFCTFGSRLVSPGCYVFSRRLDRFCSALSSMLERHLSTHMWKKIPPAAEPPAHLVNSPLSAPLSPSSTGTCPRLPGPTLRPACPASMPPTKDNLVPSYPAGSPSVAAACSQAECMGGSQAITSPLPANTPSPSFSKLPPSKASKSSKGKDGVEVEAPSRKRKLSPGPTTLKRTCILEPTGKGKPSGCRGLSAKTKTALSMGLNGTMGPRVKRAGPLDCRGSPHQLPTPVKASQLENRGAAGHPAKALPTNCLSEEEVAKKRKNLATYCRPVKAKHCQAGAPADVACSVRRKKPGPALAFEEKCSTLKSKAH", "length": 722 }, "evidence": [ { "id": "A0A8V1AA61", "url": "https://omabrowser.org/oma/group/A0A8V1AA61/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 501, "end_pos": 503, "annotation": "n_glycosylation_sequon" }, { "start_pos": 615, "end_pos": 617, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AA61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA61" }, { "id": "PS51505", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51505" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SCA7", "eco_id": "ECO_0000259", "start_pos": 240, "end_pos": 307, "start_aa": "Lys", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 217, 477 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 501, "end_pos": 503 }, { "start_pos": 615, "end_pos": 617 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AA77-1", "uniprot_ac": "A0A8V1AA77", "uniprot_id": "A0A8V1AA77_CHICK", "mass": { "chemical_mass": 12361.0, "monoisotopic_mass": 12361.0 }, "refseq": {}, "gene_names": [ { "name": "LOC100859722", "type": "recommended", "evidence": [ { "id": "A0A8V1AA77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA77" } ] } ], "protein_names": [ { "name": "Keratin", "type": "recommended", "evidence": [ { "id": "A0A8V1AA77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA77/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AA77", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA77" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC100859722", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA77", "locus": {} } ], "crossref": [ { "id": "A0A8V1AA77", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AA77", "database": "AlphaFoldDB", "categories": [] }, { "id": "100859722", "url": "https://www.ncbi.nlm.nih.gov/gene/100859722", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003461", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003461", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:100859722", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100859722", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RSNIACP", "url": "https://omabrowser.org/oma/group/RSNIACP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AA77", "url": "https://www.orthodb.org/?gene=A0A8V1AA77", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31203", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31203", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31203:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31203:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02422", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02422", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001264904", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264904", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AA77", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA77", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AA77-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA77-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSCYDLCPPKTSVAVPQPIAESCNELCARQCPDSTAFIQPPPVVVTFPGPILSSFPQQAVVGSSGAPAFGGSLGLGGLYGAGATQGSGGLCTFGRPYVSPAYSPCALPRYSRKLWDTCGPC", "length": 121, "header": "tr|A0A8V1AA77-1|A0A8V1AA77_CHICK Isoform 1 of Keratin OS=Gallus gallus OX=9031 GN=LOC100859722 PE=3 SV=1 CANONICAL=A0A8V1AA77-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AA77-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA77/entry#A0A8V1AA77-1", "sequence": { "sequence": "MSCYDLCPPKTSVAVPQPIAESCNELCARQCPDSTAFIQPPPVVVTFPGPILSSFPQQAVVGSSGAPAFGGSLGLGGLYGAGATQGSGGLCTFGRPYVSPAYSPCALPRYSRKLWDTCGPC", "length": 121, "header": "tr|A0A8V1AA77-1|A0A8V1AA77_CHICK Isoform 1 of Keratin OS=Gallus gallus OX=9031 GN=LOC100859722 PE=3 SV=1 CANONICAL=A0A8V1AA77-1" }, "locus": { "chromosome": "25", "start_pos": 1425087, "end_pos": 1424725, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069616.1", "url": "https://www.ensembl.org/id/ENSGALT00010069616.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042877.1", "url": "https://www.ensembl.org/id/ENSGALP00010042877.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:100859722", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100859722", "resource": "KEGG Pathway" } ], "orthologs": [], 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"AVAAAGVRFQLVAARHQPHLRVRSGAAPGAVGRVLPGRAGAAAAGVRRARRLFPHLPARHQTGRGGRAQPHLPGHHHLQPQRVPLLQDHPQRHVPRGRAAGAAQRALRDQQPAAGRARRAGGAARQGQLQELQGQTLQHGRVLQPHRPRPGRHAAAVLLPRRRLLRTQLQRDLHPPGQVLHLQLGAAGHGAADHAAGRRGERAGADAQHPAGGVPPRLGGHGRDVVRGGGEGADPQPAGAALHRPAGLRRGARLPDLRVVPAAAASPPAAWTARRATWPRTATAAWCTCPATPTSARRSSTRSARTPRWVRTGPDRCGGGGKGGGGGGTDPTPPSPGADFLVKKDSEYCACRTPCDTVRYGKELSMVKIPSKASARYLARKFNKTEQYIADNVLVLDIFFEALNYEMIEQKKAYEVAGLLGDIGGQMGLFIGASLLTILEIFDYLYEVFRDKLIGFYKDKKRMRRGSSTTLEHPAVPGSPAATLPPRTPIGPCAATRTVSPSPRTCYLVTRL", "length": 512, "header": "tr|A0A8V1AA82-1|A0A8V1AA82_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN=ASIC1L PE=3 SV=1 CANONICAL=A0A8V1AA82-1" }, "locus": { "chromosome": "2", "start_pos": 326377, "end_pos": 320930, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065868.1", "url": "https://www.ensembl.org/id/ENSGALT00010065868.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040134.1", "url": 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"function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052533.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_003640698.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003640698", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003640698" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AA89", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA89" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "GIMAP6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA89", "locus": {} } ], "crossref": [ { "id": "cd01852", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01852", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "420413", "url": "https://www.ncbi.nlm.nih.gov/gene/420413", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006703", "url": 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Classification" ] }, { "id": "PTHR10903:SF73", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10903:SF73", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04548", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04548", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003640698", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003640698", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AA89", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA89", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AA89-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA89-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": 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CANONICAL=A0A8V1AA89-1" }, "locus": { "chromosome": "2", "start_pos": 4077749, "end_pos": 4077555, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010062045.1", "url": "https://www.ensembl.org/id/ENSGALT00010062045.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038326.1", "url": "https://www.ensembl.org/id/ENSGALP00010038326.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:420413", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420413", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q8BWF2-1", "protein_name": "GTPase IMAP family member 5", "gene_name": "Gimap5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": 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"MEDHGFEELSTRTHDLNVRRLTKGNINFLLSTGQETYSVEDSGLLRILLVGKSGCGKSATGNSILRRPAFESRLRGQSVTRTSQAEMGTWEGRSFLVVDTPPIFESKIQNQDMDKDIGNCYLMCAPGPHVLLLVTQLGRYTVEDAMAVRMVKQIFGVGVMRYMIVLFTHKEDLADESLEEFVTHTGNLDLHRLVQECGRRYCAFNNKASGEEQQGQLAELMALVRRLEQEHEGSFHSNDLFVYTQVFLRGGYSEHQEPYKFYLTKVRQEVEKQKRELEEQEGSWMAKMLCRVTSCLDWHIAVSVLLIVLGLTLLITLINMYIGRWK", "length": 326 }, "evidence": [ { "id": "A0A8V1AA89", "url": "https://omabrowser.org/oma/group/A0A8V1AA89/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AA89", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA89" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AA89", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA89" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AA89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA89" }, { "id": "PS51720", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51720" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "AIG1-type G", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 201, "start_aa": "Met", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], 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"sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AA99-1", "uniprot_ac": "A0A8V1AA99", "uniprot_id": "A0A8V1AA99_CHICK", "mass": { "chemical_mass": 46738.0, "monoisotopic_mass": 46738.0 }, "refseq": {}, "gene_names": [ { "name": "CRNN", "type": "recommended", "evidence": [ { "id": "A0A8V1AA99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA99" } ] } ], "protein_names": [ { "name": "Cornulin", "type": "synonym", "evidence": [ { "id": "A0A8V1AA99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA99/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AA99", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA99" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CRNN", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA99", "locus": { "chromosome": "25", "start_pos": 1294804, "end_pos": 1298265, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027728", "url": "https://www.ensembl.org/id/ENSGALG00010027728" } ] } } ], "crossref": [ { "id": "A0A8V1AA99", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AA99", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00213", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00213", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR002048", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002048", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013787", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013787", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018247", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018247", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034325", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034325", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AA99", "url": "https://www.orthodb.org/?gene=A0A8V1AA99", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AFN5", "url": "https://www.orthodb.org/?gene=A0A8V1AFN5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11639", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11639", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11639:SF26", "url": 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"MMLLYIRLLGAGWLHTALFSPSRLPLFCGEMAQLQENINGIITVFYTYARSDGDSSTLSRGELRQLIEQEFGDVITDAWDPRTVDEVLFFLDEDSSGKIDFGEFLSLIFRVAKACHRQLQQYLEPEYDQELTVQEEADGEQQHKQVLEQGVSEQVQEGGTPQQDQDTQQHQESEEPKNHQGTQQKQEGGTPKYQDTQKIEKSEIPKVQDTQKTQEVETPKNNESTQQKKSETPKDNQDTHQDDRAKTPEQSPKRGENVVTKSPEEDRNTQEAEKTPKHDPKPHQDKVTETPKLGQDHHQRHELKPAEQSHTSPTKTPGGTTDKTKDHVAHWQDPSPKGTQELPPPVRGTSPHPDPQPSGTQHDPAHLPNPTVIVREGSGAEAERVPGQQQHGAHGKGKHVAEQEHLQPQWPPRK", "length": 414, "header": "tr|A0A8V1AA99-1|A0A8V1AA99_CHICK Isoform 1 of Cornulin OS=Gallus gallus OX=9031 GN=CRNN PE=4 SV=1 CANONICAL=A0A8V1AA99-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AA99-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA99/entry#A0A8V1AA99-1", "sequence": { "sequence": "MMLLYIRLLGAGWLHTALFSPSRLPLFCGEMAQLQENINGIITVFYTYARSDGDSSTLSRGELRQLIEQEFGDVITDAWDPRTVDEVLFFLDEDSSGKIDFGEFLSLIFRVAKACHRQLQQYLEPEYDQELTVQEEADGEQQHKQVLEQGVSEQVQEGGTPQQDQDTQQHQESEEPKNHQGTQQKQEGGTPKYQDTQKIEKSEIPKVQDTQKTQEVETPKNNESTQQKKSETPKDNQDTHQDDRAKTPEQSPKRGENVVTKSPEEDRNTQEAEKTPKHDPKPHQDKVTETPKLGQDHHQRHELKPAEQSHTSPTKTPGGTTDKTKDHVAHWQDPSPKGTQELPPPVRGTSPHPDPQPSGTQHDPAHLPNPTVIVREGSGAEAERVPGQQQHGAHGKGKHVAEQEHLQPQWPPRK", "length": 414, "header": "tr|A0A8V1AA99-1|A0A8V1AA99_CHICK Isoform 1 of Cornulin OS=Gallus gallus OX=9031 GN=CRNN PE=4 SV=1 CANONICAL=A0A8V1AA99-1" }, "locus": { "chromosome": "25", "start_pos": 1296584, "end_pos": 1295023, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067217.1", "url": "https://www.ensembl.org/id/ENSGALT00010067217.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041121.1", "url": "https://www.ensembl.org/id/ENSGALP00010041121.1" } ] } }, { "isoform_ac": "A0A8V1AFN5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA99/entry#A0A8V1AFN5-1", "sequence": { "sequence": "MMLLYIRLLGAGWLHTALFSPRLPLFCGEMAQLQENINGIITVFYTYARSDGDSSTLSRGELRQLIEQEFGDVITDAWDPRTVDEVLFFLDEDSSGKIDFGEFLSLIFRVAKACHRQLQQYLEPEYDQELTVQEEADGEQQHKQVLEQGVSEQVQEGGTPQQDQDTQQHQESEEPKNHQGTQQKQEGGTPKYQDTQKIEKSEIPKVQDTQKTQEVETPKNNESTQQKKSETPKDNQDTHQDDRAKTPEQSPKRGENVVTKSPEEDRNTQEAEKTPKHDPKPHQDKVTETPKLGQDHHQRHELKPAEQSHTSPTKTPGGTTDKTKDHVAHWQDPSPKGTQELPPPVRGTSPHPDPQPSGTQHDPAHLPNPTVIVREGSGAEAERVPGQQQHGAHGKGKHVAEQEHLQPQWPPRK", "length": 413, "header": "tr|A0A8V1AFN5-1|A0A8V1AFN5_CHICK Computationally mapped isoform of Cornulin OS=Gallus gallus OX=9031 GN=CRNN PE=4 SV=1 CANONICAL=A0A8V1AA99-1" }, "locus": { "chromosome": "25", "start_pos": 1296584, "end_pos": 1295023, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067218.1", "url": "https://www.ensembl.org/id/ENSGALT00010067218.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041122.1", "url": "https://www.ensembl.org/id/ENSGALP00010041122.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction", "id": "GO:0051896", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051896", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AA99", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA99" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "transition metal ion binding", "id": "GO:0046914", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046914", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AA99", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA99" } ], "pmid": "" }, { "name": "calcium-dependent protein binding", "id": "GO:0048306", "url": 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Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052558.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_001234927", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001234927" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAB7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAB7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "HOXB13", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAB7", "locus": { "chromosome": "27", "start_pos": 3352798, "end_pos": 3350872, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010026052", "url": "https://www.ensembl.org/id/ENSGALG00010026052" } ] } } ], "crossref": [ { "id": "A0A8V1AAB7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AAB7", "database": 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"database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:771676", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:771676", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HPPDGCA", "url": "https://omabrowser.org/oma/group/HPPDGCA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AAB7", "url": "https://www.orthodb.org/?gene=A0A8V1AAB7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45804", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45804", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45804:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45804:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00046", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00046", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12284", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12284", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_001234927", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001234927", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AAB7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAB7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AAB7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAB7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQPPGLEGLLAAGGFAGGQGRVLPPPPAIGCPSPPPGMNPGYPTEEAAKPCLTAPPGPAAPPGPTASAPLPYGYLGGGYYSCRVARSALKAGPAQGPFPPEKYLDPPAGSEDFQSRPAELAFYPGYGAPYQPVAGYLDVSVVPGLGGPGEPRHEALLPVDGYHQPWALGGSWSGQMCCPKEQGQAGYLLKSAFADAAAPLPPDGCAFRRGRKKRVPYSKGQLKELEKEYASSKFITRDKRRKISAATNLTERQITIWFQNRRVKEKKVVAKIKSSSGAQ", "length": 279, "header": "tr|A0A8V1AAB7-1|A0A8V1AAB7_CHICK Isoform 1 of Homeobox B13 OS=Gallus gallus OX=9031 GN=HOXB13 PE=3 SV=1 CANONICAL=A0A8V1AAB7-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AAB7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAB7/entry#A0A8V1AAB7-1", "sequence": { "sequence": "MQPPGLEGLLAAGGFAGGQGRVLPPPPAIGCPSPPPGMNPGYPTEEAAKPCLTAPPGPAAPPGPTASAPLPYGYLGGGYYSCRVARSALKAGPAQGPFPPEKYLDPPAGSEDFQSRPAELAFYPGYGAPYQPVAGYLDVSVVPGLGGPGEPRHEALLPVDGYHQPWALGGSWSGQMCCPKEQGQAGYLLKSAFADAAAPLPPDGCAFRRGRKKRVPYSKGQLKELEKEYASSKFITRDKRRKISAATNLTERQITIWFQNRRVKEKKVVAKIKSSSGAQ", "length": 279, "header": "tr|A0A8V1AAB7-1|A0A8V1AAB7_CHICK Isoform 1 of Homeobox B13 OS=Gallus gallus OX=9031 GN=HOXB13 PE=3 SV=1 CANONICAL=A0A8V1AAB7-1" }, "locus": { "chromosome": "27", "start_pos": 3352520, "end_pos": 3350930, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063516.1", "url": "https://www.ensembl.org/id/ENSGALT00010063516.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039208.1", "url": "https://www.ensembl.org/id/ENSGALP00010039208.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 65, "start_aa": "Thr", "end_pos": 65, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr65", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:771676", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:771676", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1UR05-1", "protein_name": "Homeobox B13", "gene_name": "HOXB13", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEPGNYATLDGAKEIEGLLGAGGSRNLVAHSPLTSHPAAAPTLMPAVNYAPLDLPGSAEPPKQCHPCSGVPQGASPAPVPYGYFGGGYYSCRVSRSSLKPCAQGATLAAYPAETPTAGEEYPSRPTEFAFYPGYPGPYQPMASYLDVSVVQTLGTPAEPRHDSLLPVDSYQPWALTGGWNSQVCCQGEQNPSGSFWKAAFADSSAQHPPEGCAFRRGRKKRIPYSKGQLRELEREYSANKFITKDKRRKISAATSLSERQITIWFQNRRVKEKKVLAKVKTSATP", "length": 285 }, "evidence": [ { "id": "A0A8V1AAB7", "url": "https://omabrowser.org/oma/group/A0A8V1AAB7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "D3ZWL5-1", "protein_name": "Homeo box B13", "gene_name": "Hoxb13", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEPGNYATLDGAKDIEGLLGAGGGRNLVAHSSPLASHPAAPTLMPTVNYAPLDLPGSAEPPKQCHPCPGVPQGASPAPVPYGYFGGGYYSCRVSRSSLKPCAQTATLATYPSETPAPGEEYPSRPTEFAFYPGYPGPYQPMASYLDVSVVQTLGAPGEPRHDSLLPVDSYQPWALAGGWNSQMCCQGEQNPPGPFWKAAFAEPSVQHPPPDGCAFRRGRKKRIPYSKGQLRELEREYAANKFITKDKRRKISAATSLSERQITIWFQNRRVKEKKVLAKVKTSTTP", "length": 286 }, "evidence": [ { "id": "A0A8V1AAB7", "url": "https://omabrowser.org/oma/group/A0A8V1AAB7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1BPB2-1", "protein_name": "Homeobox B13", "gene_name": "HOXB13", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MEPSNYTTLDGAKEIEGLLGAGGSRNLVTHSPLTSHPTSAPTLMPAVNYAPLDLPGSAEPPKQCHPCPGVPQGASPAPVPYGYFGGGYYSCRVSRSSLKPCAQAATLAAYPAETPTSGEEYPSRPTEFAFYPGYPGPYQPMASYLDVSVVQTLGAPGEPRHDSLLPVDSYQPWALTGGWNSQMCCQGEQNPPGPFWKAAFADSSSQHPPEGCTFRRGRKKRIPYSKGQLRELEREYSANKFITKDKRRKISAATSLSERQITIWFQNRRVKEKKVLAKVKTSAPP", "length": 285 }, "evidence": [ { "id": "A0A8V1AAB7", "url": "https://omabrowser.org/oma/group/A0A8V1AAB7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3H5S1-1", "protein_name": "Homeobox protein Hox-B13", "gene_name": "Hoxb13", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": 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"A0A8V1AAD4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAD4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAD4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAD4" } ], "pmid": "" }, { "name": "sarcolemma", "id": "GO:0042383", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042383", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAD4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAD4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "fructose transmembrane transporter activity", "id": "GO:0005353", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005353", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAD4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAD4" } ], "pmid": "" }, { "name": "D-glucose transmembrane transporter activity", "id": "GO:0055056", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055056", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAD4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAD4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 144, "end_pos": 146, "annotation": "n_glycosylation_sequon" }, { "start_pos": 32, "end_pos": 34, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "60372", "name": "", "equation": "D-fructose(out) = D-fructose(in)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "60372", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/60372" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AAD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAD4" }, { "id": "PS50850", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50850" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Major facilitator superfamily (MFS) profile", "eco_id": "ECO_0000259", "start_pos": 2, "end_pos": 445, "start_aa": "Val", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 144, "end_pos": 146 }, { "start_pos": 32, "end_pos": 34 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AAD5-1", "uniprot_ac": "A0A8V1AAD5", "uniprot_id": "A0A8V1AAD5_CHICK", "mass": { "chemical_mass": 59229.0, "monoisotopic_mass": 59229.0 }, "refseq": { "ac": "XP_425830", "name": "synaptotagmin-6", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_425830" }, "gene_names": [ { "name": "SYT6", "type": "recommended", "evidence": [ { "id": "A0A8V1AAD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAD5" } ] }, { "name": "SYT6", "type": "synonym", "evidence": [ { "id": "XP_425830", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_425830" } ] } ], "protein_names": [ { "name": "Synaptotagmin 6", "type": "synonym", "evidence": [ { "id": "A0A8V1AAD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAD5/entry#names_and_taxonomy" } ] }, { "name": "synaptotagmin-6", "type": "synonym", "evidence": [ { "id": "XP_425830", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_425830" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052557.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Jun 19, 2013 this sequence version replaced XP_425830.3. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_425830", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_425830" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAD5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAD5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SYT6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAD5", "locus": { "chromosome": "26", "start_pos": 3849207, "end_pos": 3877828, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010025434", "url": "https://www.ensembl.org/id/ENSGALG00010025434" } ] } } ], "crossref": [ { "id": "A0A8V1AAD5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AAD5", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd08385", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08385", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd08403", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08403", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "428270", "url": "https://www.ncbi.nlm.nih.gov/gene/428270", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000008", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000008", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001565", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001565", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035892", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035892", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:428270", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428270", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VMRVGCN", "url": "https://omabrowser.org/oma/group/VMRVGCN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AAD5", "url": "https://www.orthodb.org/?gene=A0A8V1AAD5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10024", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10024", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10024:SF45", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10024:SF45", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00168", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00168", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_425830", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_425830", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AAD5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAD5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AAD5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAD5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSGTEDDSRCQKAVRIITELCRKKSLPALHLNTCREFLLPSDQSLSISEPELSVSLLAVIVIVCGLALVAVFLFLFWKLCWVPWRNKALSSHLAVLQSEAGCNKENMADKLQDTGTISFLEAAVKISHTSPDIPAEVQMSMKDHILRRTRIQRQTTEPASSTRHISFKRHLPRQMHVSSMDYGMDPPAIAEQPTSIGRIKPELYKQKSVDSEDPKKEAAKTCGKINFTLKYDYENETLTVRILRAFDLPAKDFCGSSDPYVKIYLLPDRKRKFQTRVHRKTLNPTFDESFHFPVPHEELVSRKLHLSVFDFDRFSRHDMIGEVILENLFEDSDLSRETSVWKDIQYATTESVDLGEIMFSLCYLPTAGRLTLTVIKCRNLKAMDITGYSDPYVKVSLLCDGRRLKKKKTTIKKNTLNPTYNEAIIFDIPPENMDQVSLLISVMDYDRVGHNEIIGVCRVGVNAEGLGRDHWNEMLAYPRKPIAHWHPLVEVKKSFKEWQGRAASFDSQSSCPSPKPPPTP", "length": 520, "header": "tr|A0A8V1AAD5-1|A0A8V1AAD5_CHICK Isoform 1 of Synaptotagmin 6 OS=Gallus gallus OX=9031 GN=SYT6 PE=3 SV=1 CANONICAL=A0A8V1AAD5-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AAD5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAD5/entry#A0A8V1AAD5-1", "sequence": { "sequence": "MSGTEDDSRCQKAVRIITELCRKKSLPALHLNTCREFLLPSDQSLSISEPELSVSLLAVIVIVCGLALVAVFLFLFWKLCWVPWRNKALSSHLAVLQSEAGCNKENMADKLQDTGTISFLEAAVKISHTSPDIPAEVQMSMKDHILRRTRIQRQTTEPASSTRHISFKRHLPRQMHVSSMDYGMDPPAIAEQPTSIGRIKPELYKQKSVDSEDPKKEAAKTCGKINFTLKYDYENETLTVRILRAFDLPAKDFCGSSDPYVKIYLLPDRKRKFQTRVHRKTLNPTFDESFHFPVPHEELVSRKLHLSVFDFDRFSRHDMIGEVILENLFEDSDLSRETSVWKDIQYATTESVDLGEIMFSLCYLPTAGRLTLTVIKCRNLKAMDITGYSDPYVKVSLLCDGRRLKKKKTTIKKNTLNPTYNEAIIFDIPPENMDQVSLLISVMDYDRVGHNEIIGVCRVGVNAEGLGRDHWNEMLAYPRKPIAHWHPLVEVKKSFKEWQGRAASFDSQSSCPSPKPPPTP", "length": 520, "header": "tr|A0A8V1AAD5-1|A0A8V1AAD5_CHICK Isoform 1 of Synaptotagmin 6 OS=Gallus gallus OX=9031 GN=SYT6 PE=3 SV=1 CANONICAL=A0A8V1AAD5-1" }, "locus": { "chromosome": "26", "start_pos": 3877642, "end_pos": 3850658, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010062100.1", "url": "https://www.ensembl.org/id/ENSGALT00010062100.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038381.1", "url": "https://www.ensembl.org/id/ENSGALP00010038381.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 519, "start_aa": "Thr", "end_pos": 519, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr519", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:428270", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428270", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q5T7P8-1", "protein_name": "Synaptotagmin-6", "gene_name": "SYT6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSGVWGAGGPRCQEALAVLASLCRARPPPLGLDVETCRSFELQPPERSPSAAGAGTSVSLLAVVVIVCGVALVAVFLFLFWKLCWMPWRNKEASSPSSANPPLEALQSPSFRGNMADKLKDPSTLGFLEAAVKISHTSPDIPAEVQMSVKEHIMRHTRLQRQTTEPASSTRHTSFKRHLPRQMHVSSVDYGNELPPAAEQPTSIGRIKPELYKQKSVDGEDAKSEATKSCGKINFSLRYDYETETLIVRILKAFDLPAKDFCGSSDPYVKIYLLPDRKCKLQTRVHRKTLNPTFDENFHFPVPYEELADRKLHLSVFDFDRFSRHDMIGEVILDNLFEASDLSRETSIWKDIQYATSESVDLGEIMFSLCYLPTAGRLTLTVIKCRNLKAMDITGYSDPYVKVSLLCDGRRLKKKKTTIKKNTLNPVYNEAIIFDIPPENMDQVSLLISVMDYDRVGHNEIIGVCRVGITAEGLGRDHWNEMLAYPRKPIAHWHSLVEVKKSFKEGNPRL", "length": 510 }, "evidence": [ { "id": "A0A8V1AAD5", "url": "https://omabrowser.org/oma/group/A0A8V1AAD5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q62746-1", "protein_name": "Synaptotagmin-6", "gene_name": "Syt6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSGVWGAGGPRCQAALAVLASLCRARPPPLGLDVETCQSFELQPPEQSPSAADSGTSVSLLAVVVIVCGVALVAVFFFLFWKLCWMPWRNKEASSPSSANPASEILQSPSSRGNMADKLKDPSALGFLEAAVKISHTSPDIPAEVQMSVKEHIMRHTKLQRQTTEPASSTRHTSFKRHLPRQMHVSSVDYGNELPPAAAEQPTSIGRIKPELYKQKSVDGDEAKSEAAKSCGKINFSLRYDYESETLIVRILKAFDLPAKDFCGSSDPYVKIYLLPDRKCKLQTRVHRKTLNPTFDENFHFPVPYEELADRKLHLSVFDFDRFSRHDMIGEVILDNLFEASDLSRETSIWKDIQYATSESVDLGEIMFSLCYLPTAGRLTLTVIKCRNLKAMDITGYSDPYVKVSLLCDGRRLKKKKTTIKKNTLNPVYNEAIIFDIPPENMDQVSLLISVMDYDRVGHNEIIGVCRVGISAEGLGRDHWNEMLAYPRKPIAHWHCLAEVKKSFKEGTPRL", "length": 511 }, "evidence": [ { "id": "A0A8V1AAD5", "url": "https://omabrowser.org/oma/group/A0A8V1AAD5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9R0N8-1", "protein_name": "Synaptotagmin-6", "gene_name": "Syt6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSGVWGAGGPRCQAALAVLASLCRARPPPLGLDVETCRSFELQSPEQSPSAADSGTSVSLLAVVVIVCGVALVAVFLFLFWKLCWMPWRKKEASSPSSANPASETLQSPSSRGNMADKLKDPSALGFLEAAVKISHTSPDIPAEVQMSVKEHIMRHTKLQRQTTEPASSTRHTSFKRHLPRQMHVSSVDYGNELPPAAAEQPTSIGRIKPELYKQKSVDGDDAKSEAAKSCGKINFSLRYDYESETLIVRILKAFDLPAKDFCGSSDPYVKIYLLPDRKCKLQTRVHRKTLNPTFDENFHFPVPYEELADRKLHLSVFDFDRFSRHDMIGEVILDNLFEASDLSRETSIWKDIQYATSESVDLGEIMFSLCYLPTAGRLTLTVIKCRNLKAMDITGYSDPYVKVSLLCDGRRLKKKKTTIKKNTLNPIYNEAIIFDIPPENMDQVSLLISVMDYDRVGHNEIIGVCRVGINAEGLGRDHWNEMLAYPRKPIAHWHSLVEVKKSFKEGTPRL", "length": 511 }, "evidence": [ { "id": "A0A8V1AAD5", "url": "https://omabrowser.org/oma/group/A0A8V1AAD5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAD5", "url": 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"id": "A0A8V1AAD5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAD5" } ], "pmid": "" }, { "name": "syntaxin binding", "id": "GO:0019905", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019905", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAD5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAD5" } ], "pmid": "" }, { "name": "calcium-dependent phospholipid binding", "id": "GO:0005544", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005544", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAD5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAD5" } ], "pmid": "" }, { "name": "clathrin binding", "id": "GO:0030276", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030276", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAD5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAD5" } ], "pmid": "" }, { "name": "SNARE binding", "id": "GO:0000149", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000149", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAD5", 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] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 233, "start_aa": "Thr", "end_pos": 233, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr233", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 258, "start_aa": "Thr", "end_pos": 258, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr258", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", 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This record is derived from a genomic sequence (NC_052597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Mar 1, 2022 this sequence version replaced XP_040546596.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040546596", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040546596" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAE8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAE8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC431321", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAE8", "locus": {} } ], "crossref": [ { "id": "A0A8V1AAE8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AAE8", "database": "AlphaFoldDB", "categories": [] }, { "id": "431321", "url": "https://www.ncbi.nlm.nih.gov/gene/431321", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003461", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003461", "database": 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"o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AAF5-1", "uniprot_ac": "A0A8V1AAF5", "uniprot_id": "A0A8V1AAF5_CHICK", "mass": { "chemical_mass": 66500.0, "monoisotopic_mass": 66500.0 }, "refseq": { "ac": "NP_001376447", "name": "leucine-rich repeat-containing protein 43", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376447" }, "gene_names": [ { "name": "LRRC43", "type": "recommended", "evidence": [ { "id": "A0A8V1AAF5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAF5" } ] }, { "name": "LRRC43", "type": "synonym", "evidence": [ { "id": "NP_001376447", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376447" } ] } ], "protein_names": [ { "name": "Leucine rich repeat containing 43", "type": "synonym", "evidence": [ { "id": "A0A8V1AAF5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAF5/entry#names_and_taxonomy" } ] }, { "name": "leucine-rich repeat-containing protein 43", "type": "synonym", "evidence": [ { "id": "NP_001376447", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376447" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992432 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000260.1. On Oct 6, 2021 this sequence version replaced NP_001376447.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001376447", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376447" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAF5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAF5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LRRC43", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAF5", "locus": { "chromosome": "15", "start_pos": 5809212, "end_pos": 5802084, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010025451", "url": "https://www.ensembl.org/id/ENSGALG00010025451" } ] } } ], "crossref": [ { "id": "A0A8V1AAF5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AAF5", "database": "AlphaFoldDB", "categories": [] }, { "id": "416859", "url": "https://www.ncbi.nlm.nih.gov/gene/416859", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR060201", "url": "https://www.ebi.ac.uk/interpro/entry/IPR060201", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR060203", "url": "https://www.ebi.ac.uk/interpro/entry/IPR060203", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "AEVIPCN", "url": "https://omabrowser.org/oma/group/AEVIPCN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AAF5", "url": "https://www.orthodb.org/?gene=A0A8V1AAF5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15454", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15454", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15454:SF19", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15454:SF19", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF28328", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF28328", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF28335", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF28335", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001376447", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376447", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AAF5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAF5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AAF5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAF5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAPGPHSLSAAFQKHLQLLGLRDFPCGLGSWNKSRFVTYAGSSGQEEERPLGEESPEALLELLSDPHSPWALPPGCSPEDQRLRDVAVLAPQLTRGTRVLQLFRSLRIVGKDVEEVDEGLLQLQRLEELTLCANQISRITSANLPRTLKVLELCCNAVADLQGLCAQPPPELQHLGLGYNRLHGPLQDKHLTADFWPNLISLDLSFNNLTDLFGLVSQLSSLKKLRILVLQGNPLALIPTYRGFIVDSLPKLSFLDDIHIGLDERYQFRGLSKQPELIKNEAQVVVSIGKIKGVPDPSTLQELEIGSEAPVITYSYCVTYKFAGEETEDVVTEVKVHQSPVVATPDMDNSAWDVREMKGQQECAAMEDPAAHTAKVFVTPGEPWADTIDCSYRKEHTAKDLVGLKDYLRAGTIVSVVEEKVLWWPVSADSEENAVKSGKERQGLKKESTKGPGPRDKQKKKKKKEKPRELRSDPPIRRILGSERVALEALLATEALVATVCDFGILITEQLLQSPSQEEKLDKKKGKDKSKKTKAKKESQKATAPAKGKRKNRRPAEQEEECGLQPVPLTVEFQVQLLRWPTAGAQHRDSMTEAEGKAQ", "length": 600, "header": "tr|A0A8V1AAF5-1|A0A8V1AAF5_CHICK Isoform 1 of Leucine rich repeat containing 43 OS=Gallus gallus OX=9031 GN=LRRC43 PE=4 SV=1 CANONICAL=A0A8V1AAF5-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AAF5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAF5/entry#A0A8V1AAF5-1", "sequence": { "sequence": "MAAPGPHSLSAAFQKHLQLLGLRDFPCGLGSWNKSRFVTYAGSSGQEEERPLGEESPEALLELLSDPHSPWALPPGCSPEDQRLRDVAVLAPQLTRGTRVLQLFRSLRIVGKDVEEVDEGLLQLQRLEELTLCANQISRITSANLPRTLKVLELCCNAVADLQGLCAQPPPELQHLGLGYNRLHGPLQDKHLTADFWPNLISLDLSFNNLTDLFGLVSQLSSLKKLRILVLQGNPLALIPTYRGFIVDSLPKLSFLDDIHIGLDERYQFRGLSKQPELIKNEAQVVVSIGKIKGVPDPSTLQELEIGSEAPVITYSYCVTYKFAGEETEDVVTEVKVHQSPVVATPDMDNSAWDVREMKGQQECAAMEDPAAHTAKVFVTPGEPWADTIDCSYRKEHTAKDLVGLKDYLRAGTIVSVVEEKVLWWPVSADSEENAVKSGKERQGLKKESTKGPGPRDKQKKKKKKEKPRELRSDPPIRRILGSERVALEALLATEALVATVCDFGILITEQLLQSPSQEEKLDKKKGKDKSKKTKAKKESQKATAPAKGKRKNRRPAEQEEECGLQPVPLTVEFQVQLLRWPTAGAQHRDSMTEAEGKAQ", "length": 600, "header": "tr|A0A8V1AAF5-1|A0A8V1AAF5_CHICK Isoform 1 of Leucine rich repeat containing 43 OS=Gallus gallus OX=9031 GN=LRRC43 PE=4 SV=1 CANONICAL=A0A8V1AAF5-1" }, "locus": { "chromosome": "15", "start_pos": 5809145, "end_pos": 5802096, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010062130.1", "url": "https://www.ensembl.org/id/ENSGALT00010062130.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038401.1", "url": "https://www.ensembl.org/id/ENSGALP00010038401.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 380, "start_aa": "Thr", "end_pos": 380, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr380", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6ANQ5-1", "protein_name": "Leucine rich repeat containing 43", "gene_name": "Lrrc43", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MATRGSSASDERHLGPEDVPGTLSTAVREHLRKLCLREFPCGVGSWNKSRFLPRQYRTWRELIPKEEETVGPEEETVEALLGLVRSSHSPWAMLKDSSAEDRFLRELAIQNPLTIKDTFFYSYFRCLRVVDKGVSLVDKEILKFLKLEELVLSANKIKDIDANNLPPTLKVLELYGNLIASMECLCSPPPPNLQHLGLGHNKLLGPLESLYVTSNNWPLLVSLDLGFNDLTDLQSMILGLSTLKCLRLLVLQGNPLALVPYYRGFTVDSLARLCVLDDITVSPSEKHQFRGLNSHGDLLAREAQFVVTIGNVRGVLDSSILDPEPGPDGPFISYSYYVTYDFVEDEEKEGITSGMEELHPDSVLDEIDKPSSGMDEEEEEEEEEEEDRQEVLSVFQSQAHHRPVRQGGRHRFRPESPEVMSRELSEYIVKEMNQMAEDSGESGITEVDESETSISIHSAPLPQSIDSSEELAKLRPRLDVRLCPSPGTVLFSTMHKPWADVIPCTYEMKHTLKELIRVKAFLLSGTTVSIVEEKIISWPVVPTPVESPLPAKKGKGDKKKKEEPAKDKGPRKKKEPPRELRQDPPVLRVLGSGQVYLEPLLAGEPVVSTVCNFGVARTLETDRLTYARDSKKVKKGSKKDKSKAAAPTVESGYQPEPLSVEVQIQLHQYRSVEEAFLSLID", "length": 681 }, "evidence": [ { "id": "A0A8V1AAF5", "url": "https://omabrowser.org/oma/group/A0A8V1AAF5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q3V0L5-1", "protein_name": "Leucine-rich repeat-containing protein 43", "gene_name": "Lrrc43", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "METSESSTSDYRQTEGEGEGVPGTLSTAVCEHLRKLCLREFPCGIGSWNKSRFLPQKCRVWRELVPKEEETLVPEEETVEALLGLVRSNHSPWAMLKDASAEDRFLRELAIQNPLMIKDTFFYSYFRSLRVVNKGVSLVDKDLLKFLKLEELVLSANKIEEIDANNLPPTLKVLELYGNLIASMECLCSAPPPRLQHLGLGHNKLLGPLESLYVTSHNWPQLVSLDLGFNNLTDLQNMILGLSTLRHLRLLVLQGNPLSLVPYYRGFTIDSLAHLCVLDDITVSPNEKHQFRGLNIHGDLLAREAQFVVTIGNVRGVLDSSILDPEPGPDGPFISYSYYVTYDFVEDEDMERNVSGLVEATHHDSVLDEIDKHFSGTDEEDQQEDPLDGRHRHRGRQRFHPGSTEEMSKELSEFIAKEMSQMAEGSVESGITEVDWSETSISIHSAPLPQSIDSSEELAKLRPKIDIQLCPSPGTVLFNTVHKPWSDVIPCTYEMKHTLKELIRVKAFLLAGTTVSIVEEKILSWPVVPTPVESPLPAKKGKDNNKKKEPAKDKVHKKKKEPPRELRQDPPVLTVLGSGLVYLEPLLAGEAVVSTVCNFGVVRTLETDRLTHARDSKKVKKSLKKDRSKTVPPTMESGYQPEPLSVEVQIQLHQYRSVEEAFLSLID", "length": 667 }, "evidence": [ { "id": "A0A8V1AAF5", "url": "https://omabrowser.org/oma/group/A0A8V1AAF5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8N309-1", "protein_name": "Leucine-rich repeat-containing protein 43", "gene_name": "LRRC43", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEASYESESESESEAGPGTQRPGTGTVSAAVREHLRKLCLREFPCGAGSWNKSRFLPQTWRTWRELVPREEDVVSPGEETVEALLGLVRSRHSPWALLNNSNAEDSFLRELAIRNPLTITDTFFYSYFRSLRVIDKKVTLVDKDLLKFLKLEELVLSANRIKEVDATNLPPTLKVLELYGNEISSMECLCAHPPAGLQHLGLGHNKLLGPLESLYVTANHWPNLVSLDLGFNDLTDLQSMVTSLRTLRHLRLLVLQGNPLALVPYYRGLTIDSLAQLCVLDDITVSPNEKHLFRGLSLNGDLLAQEAQFVVTIGNIRGVLDTSVLDPEPRPEGPFITYNYYVTYDFVKDEEGEMNESAGVLAEIVKPSPSLELLVEESPEEVVEDVIEDIVEEVTEEVEGSLESEVEESGESELSVISGPSTILQMPRASAEELAKLRLRIDPRLCPSPGTVLFSTAHKPWAEVIPCSYEMQHSLRDLVPLKAFLLAGTTVTIVEEKILSWPVVLPAVDSPLSAKKGKGEKDKKGKEKDRTGKGEKEPAKEWKVLKKKKEPPKELRQDPPILQVLGRGLVILEPLLAGEPLVSTVCNFGVVRTLTSDRLTLARDSKKIKKVAKKEKPKAVIPIYEGDYHPEPLTVEVQIQLNQCRSAEEALRMFAV", "length": 656 }, "evidence": [ { "id": "A0A8V1AAF5", "url": "https://omabrowser.org/oma/group/A0A8V1AAF5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 209, "end_pos": 211, "annotation": "n_glycosylation_sequon" }, { "start_pos": 33, "end_pos": 35, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AAF5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAF5" }, { "id": "PF28335", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF28335" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Leucine-rich repeat-containing protein 43 C-terminal", "eco_id": "ECO_0000259", "start_pos": 283, "end_pos": 334, "start_aa": "Ala", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1AAF5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAF5" }, { "id": "PF28328", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF28328" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Leucine-rich repeat-containing protein 43 N-terminal", "eco_id": "ECO_0000259", "start_pos": 16, "end_pos": 94, "start_aa": "His", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 380 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 209, "end_pos": 211 }, { "start_pos": 33, "end_pos": 35 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": 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"n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AAG2-1", "uniprot_ac": "A0A8V1AAG2", "uniprot_id": "A0A8V1AAG2_CHICK", "mass": { "chemical_mass": 108863.0, "monoisotopic_mass": 108863.0 }, "refseq": { "ac": "XP_040542036", "name": "ADAMTS-like protein 2 isoform X8", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040542036" }, "gene_names": [ { "name": "ADAMTSL2", "type": "recommended", "evidence": [ { "id": "A0A8V1AAG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAG2" } ] }, { "name": "ADAMTSL2", "type": "synonym", "evidence": [ { "id": "XP_040542036", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040542036" } ] } ], "protein_names": [ { "name": "ADAMTS like 2", "type": "synonym", "evidence": [ { "id": "A0A8V1AAG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAG2/entry#names_and_taxonomy" } ] }, { "name": "ADAMTS-like protein 2 isoform X8", "type": "synonym", "evidence": [ { "id": "XP_040542036", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040542036" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052589.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040542036", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040542036" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAG2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAG2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ADAMTSL2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAG2", "locus": { "chromosome": "17", "start_pos": 7598173, "end_pos": 7577950, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028876", "url": "https://www.ensembl.org/id/ENSGALG00010028876" } ] } } ], "crossref": [ { "id": "A0A8V1AAG2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AAG2", "database": "AlphaFoldDB", "categories": [] }, { "id": "417147", "url": "https://www.ncbi.nlm.nih.gov/gene/417147", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000884", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000884", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010294", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010294", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010909", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010909", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013273", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013273", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036383", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036383", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045371", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045371", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050439", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050439", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AAG2", "url": "https://www.orthodb.org/?gene=A0A8V1AAG2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AHW3", "url": "https://www.orthodb.org/?gene=A0A8V1AHW3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13723", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13723", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13723:SF147", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13723:SF147", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00090", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00090", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF05986", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05986", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08686", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08686", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19030", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19030", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19236", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19236", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-5173214", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5173214", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_040542036", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040542036", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AAG2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAG2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AAG2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAG2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHW3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHW3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHW3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHW3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQVPPLDQALAVTGGGGPPIGLHGVLLSTAWLLRRMKMFRWRWSSISVSVRSRLRAALALLVVGNVAFVIAQDLPQTSNSLEEGADVTAYWWGEWTKWTACTRSCGGGVKSQERHCLRQRRKSVSGLANKTCTGTSKRYQLCKVQECPANGRSFREEQCSSFNSHVYNGRTYQWKPLYPDDYVHISSKPCDLHCTTVDGQRQLMVQARDGTSCKYTDFRGVCVSGKCEPIGCDGILFSTHTLDKCGVCQGDGSSCTHVTGSYRKGNAHLGYSLVTHIPAGARDIQIVERKKSADVLAVADEAGYYFFNGNYKVDSPKNFNIAGTVFKYRRPMDVYETGIEYIVAQGPTNQGLNIMVWNQNGKNPSITFEYTLLRKPHSNLQPIYYTFSESDSEESREFDGDVPLGFIQHNATYFGKISRERIDLENQVFGRQDTEEDLNLSKDPNVTRSTYQTDPDDRDFDPTFTSREFLSENAITDKLLDKTSDSKELVLNMTMNSIFAQGDPINSVGSHIDSLYVDYEDSDGIVTYTINGTYMELSNSKAVNSSAETPFSNATVTMTSSQGNRTHKARNRLKLLRKGQGVSAADMYRWKLSSHEPCSSTCTTGVMSTYAMCVRYDGIEVDDTYCDAMTRPEPVHEFCAGRECQPRWETSSWSECSRTCGEGYQFRIVRCWKMISPGFDSSVYSDLCESADITRPDERKVCKNPACGPQWEMSEWSECSARCGERSVVTRDIRCSEEEKLCDASARPLAEKNCTGPPCDRQWTVSDWGPCSGGCGQGRMIRHVYCKTSDGRVVPESQCNLETKPLAIHPCGDKNCPSHWLAQDWERCNTTCGRGVKKRIVLCLEIVNGKIKTHSPTDCDVAKKPVEETTCFERPCFKWYTTPWSECTKTCGIGVRMRDVKCYQGKDIVRGCDPLVKPVGKQTCDLQPCPTEPPDDSCQDQAGTNCALAIKVNLCSHWYYSKACCRSCRTPHS", "length": 973, "header": "tr|A0A8V1AAG2-1|A0A8V1AAG2_CHICK Isoform 1 of ADAMTS like 2 OS=Gallus gallus OX=9031 GN=ADAMTSL2 PE=4 SV=1 CANONICAL=A0A8V1AAG2-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AAG2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAG2/entry#A0A8V1AAG2-1", "sequence": { "sequence": "MQVPPLDQALAVTGGGGPPIGLHGVLLSTAWLLRRMKMFRWRWSSISVSVRSRLRAALALLVVGNVAFVIAQDLPQTSNSLEEGADVTAYWWGEWTKWTACTRSCGGGVKSQERHCLRQRRKSVSGLANKTCTGTSKRYQLCKVQECPANGRSFREEQCSSFNSHVYNGRTYQWKPLYPDDYVHISSKPCDLHCTTVDGQRQLMVQARDGTSCKYTDFRGVCVSGKCEPIGCDGILFSTHTLDKCGVCQGDGSSCTHVTGSYRKGNAHLGYSLVTHIPAGARDIQIVERKKSADVLAVADEAGYYFFNGNYKVDSPKNFNIAGTVFKYRRPMDVYETGIEYIVAQGPTNQGLNIMVWNQNGKNPSITFEYTLLRKPHSNLQPIYYTFSESDSEESREFDGDVPLGFIQHNATYFGKISRERIDLENQVFGRQDTEEDLNLSKDPNVTRSTYQTDPDDRDFDPTFTSREFLSENAITDKLLDKTSDSKELVLNMTMNSIFAQGDPINSVGSHIDSLYVDYEDSDGIVTYTINGTYMELSNSKAVNSSAETPFSNATVTMTSSQGNRTHKARNRLKLLRKGQGVSAADMYRWKLSSHEPCSSTCTTGVMSTYAMCVRYDGIEVDDTYCDAMTRPEPVHEFCAGRECQPRWETSSWSECSRTCGEGYQFRIVRCWKMISPGFDSSVYSDLCESADITRPDERKVCKNPACGPQWEMSEWSECSARCGERSVVTRDIRCSEEEKLCDASARPLAEKNCTGPPCDRQWTVSDWGPCSGGCGQGRMIRHVYCKTSDGRVVPESQCNLETKPLAIHPCGDKNCPSHWLAQDWERCNTTCGRGVKKRIVLCLEIVNGKIKTHSPTDCDVAKKPVEETTCFERPCFKWYTTPWSECTKTCGIGVRMRDVKCYQGKDIVRGCDPLVKPVGKQTCDLQPCPTEPPDDSCQDQAGTNCALAIKVNLCSHWYYSKACCRSCRTPHS", "length": 973, "header": "tr|A0A8V1AAG2-1|A0A8V1AAG2_CHICK Isoform 1 of ADAMTS like 2 OS=Gallus gallus OX=9031 GN=ADAMTSL2 PE=4 SV=1 CANONICAL=A0A8V1AAG2-1" }, "locus": { "chromosome": "17", "start_pos": 7597544, "end_pos": 7578030, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069843.1", "url": "https://www.ensembl.org/id/ENSGALT00010069843.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042969.1", "url": "https://www.ensembl.org/id/ENSGALP00010042969.1" } ] } }, { "isoform_ac": "A0A8V1AHW3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAG2/entry#A0A8V1AHW3-1", "sequence": { "sequence": "MKMFRWRWSSISVSVRSRLRAALALLVVGNVAFVIAQDLPQTSNSLEEGADVTAYWWGEWTKWTACTRSCGGGVKSQERHCLRQRRKSVSGLANKTCTGTSKRYQLCKVQECPANGRSFREEQCSSFNSHVYNGRTYQWKPLYPDDYVHISSKPCDLHCTTVDGQRQLMVQARDGTSCKYTDFRGVCVSGKCEPIGCDGILFSTHTLDKCGVCQGDGSSCTHVTGSYRKGNAHLGYSLVTHIPAGARDIQIVERKKSADVLAVADEAGYYFFNGNYKVDSPKNFNIAGTVFKYRRPMDVYETGIEYIVAQGPTNQGLNIMVWNQNGKNPSITFEYTLLRKPHSNLQPIYYTFSESDSEESREFDGDVPLGFIQHNATYFGKISRERIDLENQVFGRQDTEEDLNLSKGQETNEVYERAETIDCEPKLKGKQPKDPNVTRSTYQTDPDDRDFDPTFTSREFLSENAITDKLLDKTSDSKELVLNMTMNSIFAQGDPINSVGSHIDSLYVDYEDSDGIVTYTINGTYMELSNSKAVNSSAETPFSNATVTMTSSQGNRTHKARNRLKLLRKGQGVSAADMYRWKLSSHEPCSSTCTTGVMSTYAMCVRYDGIEVDDTYCDAMTRPEPVHEFCAGRECQPRWETSSWSECSRTCGEGYQFRIVRCWKMISPGFDSSVYSDLCESADITRPDERKVCKNPACGPQWEMSEWSECSARCGERSVVTRDIRCSEEEKLCDASARPLAEKNCTGPPCDRQWTVSDWGPCSGGCGQGRMIRHVYCKTSDGRVVPESQCNLETKPLAIHPCGDKNCPSHWLAQDWERCNTTCGRGVKKRIVLCLEIVNGKIKTHSPTDCDVAKKPVEETTCFERPCFKWYTTPWSECTKTCGIGVRMRDVKCYQGKDIVRGCDPLVKPVGKQTCDLQPCPTEPPDDSCQDQAGTNCALAIKVNLCSHWYYSKACCRSCRTPHS", "length": 964, "header": "tr|A0A8V1AHW3-1|A0A8V1AAG2_CHICK Computationally mapped isoform of ADAMTS like 2 OS=Gallus gallus OX=9031 GN=ADAMTSL2 PE=4 SV=1 CANONICAL=A0A8V1AAG2-1" }, "locus": { "chromosome": "17", "start_pos": 7597544, "end_pos": 7579145, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069842.1", "url": "https://www.ensembl.org/id/ENSGALT00010069842.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042968.1", "url": "https://www.ensembl.org/id/ENSGALP00010042968.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 931, "start_aa": "Thr", "end_pos": 931, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr931", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-GGA-5173214", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5173214", "resource": "Reactome", "description": "O-glycosylation of TSR domain-containing proteins" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAG2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAG2" } ], "pmid": "" }, { "name": "extracellular matrix", "id": "GO:0031012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031012", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAG2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAG2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "extracellular matrix organization", "id": "GO:0030198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030198", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAG2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAG2" } ], "pmid": "" }, { "name": "negative regulation of transforming growth factor beta receptor signaling pathway", "id": "GO:0030512", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030512", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAG2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAG2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "microfibril binding", "id": "GO:0050436", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050436", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAG2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAG2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 129, "end_pos": 131, "annotation": "n_glycosylation_sequon" }, { "start_pos": 410, "end_pos": 412, "annotation": "n_glycosylation_sequon" }, { "start_pos": 439, "end_pos": 441, "annotation": "n_glycosylation_sequon" }, { "start_pos": 445, "end_pos": 447, "annotation": "n_glycosylation_sequon" }, { "start_pos": 492, "end_pos": 494, "annotation": "n_glycosylation_sequon" }, { "start_pos": 531, "end_pos": 533, "annotation": "n_glycosylation_sequon" }, { "start_pos": 544, "end_pos": 546, "annotation": "n_glycosylation_sequon" }, { "start_pos": 553, "end_pos": 555, "annotation": "n_glycosylation_sequon" }, { "start_pos": 564, "end_pos": 566, "annotation": "n_glycosylation_sequon" }, { "start_pos": 753, "end_pos": 755, "annotation": "n_glycosylation_sequon" }, { "start_pos": 829, "end_pos": 831, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AAG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAG2" }, { "id": "PS50900", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50900" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PLAC", "eco_id": "ECO_0000259", "start_pos": 934, "end_pos": 972, "start_aa": "Pro", "end_aa": "His", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 931 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 129, "end_pos": 131 }, { "start_pos": 410, "end_pos": 412 }, { "start_pos": 439, "end_pos": 441 }, { "start_pos": 445, "end_pos": 447 }, { "start_pos": 492, "end_pos": 494 }, { "start_pos": 531, "end_pos": 533 }, { "start_pos": 544, "end_pos": 546 }, { "start_pos": 553, "end_pos": 555 }, { "start_pos": 564, "end_pos": 566 }, { "start_pos": 753, "end_pos": 755 }, { "start_pos": 829, "end_pos": 831 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { 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"o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AAG8-1", "uniprot_ac": "A0A8V1AAG8", "uniprot_id": "A0A8V1AAG8_CHICK", "mass": { "chemical_mass": 48702.0, "monoisotopic_mass": 48702.0 }, "refseq": { "ac": "XP_004944561", "name": "osteomodulin", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004944561" }, "gene_names": [ { "name": "OMD", "type": "recommended", "evidence": [ { "id": "A0A8V1AAG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAG8" } ] }, { "name": "OMD", "type": "synonym", "evidence": [ { "id": "XP_004944561", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004944561" } ] } ], "protein_names": [ { "name": "Osteomodulin", "type": "recommended", "evidence": [ { "id": "A0A8V1AAG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAG8/entry#names_and_taxonomy" } ] }, { "name": "Keratan sulfate proteoglycan osteomodulin", "type": "synonym", "evidence": [ { "id": "A0A8V1AAG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAG8/entry#names_and_taxonomy" } ] }, { "name": "Osteoadherin", "type": "synonym", "evidence": [ { "id": "A0A8V1AAG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAG8/entry#names_and_taxonomy" } ] }, { "name": "osteomodulin", "type": "synonym", "evidence": [ { "id": "XP_004944561", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004944561" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052543.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004944561.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004944561", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004944561" } ] }, { "annotation": "May be implicated in biomineralization processes. Has a function in binding of osteoblasts via the alpha(V)beta(3)-integrin.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAG8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAG8#function" }, { "database": "UniProtKB", "id": "ARBA00060161", "url": "https://www.uniprot.org/uniprotkb/ARBA00060161#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAG8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAG8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "OMD", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAG8", "locus": { "chromosome": "12", "start_pos": 3608935, "end_pos": 3601755, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027204", "url": "https://www.ensembl.org/id/ENSGALG00010027204" } ] } } ], "crossref": [ { "id": "A0A8V1AAG8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AAG8", "database": "AlphaFoldDB", "categories": [] }, { "id": "101747586", "url": "https://www.ncbi.nlm.nih.gov/gene/101747586", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000372", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000372", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003591", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003591", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:101747586", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:101747586", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HYHHLTY", "url": "https://omabrowser.org/oma/group/HYHHLTY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AAG8", "url": "https://www.orthodb.org/?gene=A0A8V1AAG8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45712", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45712", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45712:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45712:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00560", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00560", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01462", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01462", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13855", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13855", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-2022854", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2022854", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-2022857", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2022857", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_004944561", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004944561", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AAG8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAG8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AAG8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAG8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGILSQLSILYLLWTTTVFCQYEDYDFGDEYDEPDHQQPYYSNSNPSAQAEVPHFPFPVECARECFCPPEFPLSMYCDHRKLKTIPNIPAHVQQLYLQNNDIEAVPAGPFTNVTILREINLSYNKIKFHMIDHGVFAKLSNLVQLHLHHNELDEFPFPLPSSLERLLLGFNKISKLPGIALDGLANITMLDLCSNFLDDSVLKGNPFSAMNNLMQLNLCNNKLQTMPPNLPSSLMYLSLENNSISYIPENYFSKLPKIIALRMSHNNLQNIPRNTFISLPNLIELNLGHNKLKQVFYIPRSLQHLYIEDNDIEMINVTLMCPSIDLMNINQLTYIRVDQNKLTTPISTYAFFCFPHIRTIYYGEQNSNANKSTQIRAPVFRRLLTPEEYDEIEDDHEIHDQETEEEHEAENNYFYPHFW", "length": 419, "header": "tr|A0A8V1AAG8-1|A0A8V1AAG8_CHICK Isoform 1 of Osteomodulin OS=Gallus gallus OX=9031 GN=OMD PE=3 SV=1 CANONICAL=A0A8V1AAG8-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AAG8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAG8/entry#A0A8V1AAG8-1", "sequence": { "sequence": "MGILSQLSILYLLWTTTVFCQYEDYDFGDEYDEPDHQQPYYSNSNPSAQAEVPHFPFPVECARECFCPPEFPLSMYCDHRKLKTIPNIPAHVQQLYLQNNDIEAVPAGPFTNVTILREINLSYNKIKFHMIDHGVFAKLSNLVQLHLHHNELDEFPFPLPSSLERLLLGFNKISKLPGIALDGLANITMLDLCSNFLDDSVLKGNPFSAMNNLMQLNLCNNKLQTMPPNLPSSLMYLSLENNSISYIPENYFSKLPKIIALRMSHNNLQNIPRNTFISLPNLIELNLGHNKLKQVFYIPRSLQHLYIEDNDIEMINVTLMCPSIDLMNINQLTYIRVDQNKLTTPISTYAFFCFPHIRTIYYGEQNSNANKSTQIRAPVFRRLLTPEEYDEIEDDHEIHDQETEEEHEAENNYFYPHFW", "length": 419, "header": "tr|A0A8V1AAG8-1|A0A8V1AAG8_CHICK Isoform 1 of Osteomodulin OS=Gallus gallus OX=9031 GN=OMD PE=3 SV=1 CANONICAL=A0A8V1AAG8-1" }, "locus": { "chromosome": "12", "start_pos": 3608377, "end_pos": 3606335, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065948.1", "url": "https://www.ensembl.org/id/ENSGALT00010065948.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040214.1", "url": "https://www.ensembl.org/id/ENSGALP00010040214.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:101747586", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:101747586", "resource": "KEGG Pathway" }, { "id": "R-GGA-2022854", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2022854", "resource": "Reactome", "description": "Keratan sulfate biosynthesis" }, { "id": "R-GGA-2022857", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2022857", "resource": "Reactome", "description": "Keratan sulfate degradation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0AAA9SYU0-1", "protein_name": "Osteomodulin", "gene_name": "OMD", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGFSSLVCVLFFFLGVKVYCQYESYQWDEDYDQEPDDVYQTEFQFQQNINYEAPFHQHTLGCASECFCPPNFPSSMYCDNRKLKTIPNIPAHIQQVYLQFNEIEAVTADSFINATHLKEINLSHNKIKSQKIDHGVFAKLPNLLQLHLQHNNLEDFPFPLPKSLERIFLGYNEISRLQTNAVNGLVNLTMLDLCFNKIDDSVLQEKVLAKMEKLMQLNLCNNRLESMPPGLPSSLMYLSLENNSISSIPENYFNKLPKLHALRISHNKLQDIPYNIFNLSNLIELNVGHNKLKQAFYIPRNLEHLYLENNEIENVNVTVMCPSVDPLHYHHLTHIRIDQNKLKAPISSYIFLCFPHIHTIYYGEQQSTNGQTIQLKTQVFRRFQDDGDSEDHDDHHEGPEEEGTEENIDAHYYGSQEWQETI", "length": 422 }, "evidence": [ { "id": "A0A8V1AAG8", "url": "https://omabrowser.org/oma/group/A0A8V1AAG8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1SUE2-1", "protein_name": "Osteomodulin", "gene_name": "OMD", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGFSSPVCVLLFFLGVKVYCQYESYQWDEDYDQEPDDVYQPEFQFRQNVDYRVPFPQHTLGCPSECFCPPNFPSSMYCDNRKLKTIPNIPPYIQQVYLQFNEIEAVTADSFINATHLKEINLSHNKIKSQKMDHGVFAKLSNLLQLHLHHNNLEEFPFPLPKSLERILLGYNEISRLQTNAMDGLVNLTMLDLCYNQIDDSMLQEKILGKMEKLMQLNLCNNRLESMPPGLPSSLMYLSLENNSISSIPENYFNELPKLHALRMSHNKLQDIPCNIFNLSNLVELNVGHNKLKQAFYIPRNLEHLYLENNEIENINVTVMCPSVNPLHYHHLTYIRLDQNKLKEPISSYILLCFPHIHTIYYGEQRSTNGQTIQLKTQVFRRFQDDADSEDHDDHQEGPEEEGSEEHVDPHYYGGQEWQETI", "length": 422 }, "evidence": [ { "id": "A0A8V1AAG8", "url": "https://omabrowser.org/oma/group/A0A8V1AAG8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F6NL91-1", "protein_name": "Osteomodulin", "gene_name": "omd", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTLAQLLTILCLFLLTGVLVFSQDYEETNYSDYDTDAISLPEAPPLSVTQQPDYDSQLIYSYDCARECFCPSSYPFAMYCDHQKLKEVPNIPRHIRHLYIQHNDIEEITSKPFINATSLREINLSYNKLQSSKVDKDVFKRLKDLTQLHLEHNNLEDIPSPLPKTLKRLHLGFNKISKIAADATRELTKLTVLDLGSNRLTDASIKGKILSGMKSLMQIILCNNKLKSMPADLPESIQQISLENNSIVSIPEGYFKKTPNLVSLRMPHNKLKSVAYNAFNLSKLMELHLGHNQLSKPFFVPRNLEHLYLNHNDFKDLNISLMCPSLDLGHPNMLTYIRLDNNKLSGPVDYYAYRCFPRLIMIFYGHQRKDDEDDSEKSPKKYEKPDRPKKPGGSKAIDTEV", "length": 401 }, "evidence": [ { "id": "A0A8V1AAG8", "url": "https://omabrowser.org/oma/group/A0A8V1AAG8/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "O35103-1", "protein_name": "Osteomodulin", "gene_name": "Omd", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGFLSPIYVLFFCFGVRVYCQYEAYRWDDDYDQEPNEDYDPEFQFHQNIEYGVPFYNNILGCAKECFCPTNFPTSMYCDNRKLKTIPIIPMHIQQLNLQFNDIEAVTANSFINATHLKEINLSHNKIKSQKIDYGVFAKLSNLQQLHLEHNNLEEFPFPLPKSLERLLLGYNEISILPTNAMDGLVNVTMLDLCYNHLSDSMLKEKTLSKMEKLMQLNLCNNRLESMPLGLPSSLMYLSLENNSISSIPDNYFDKLPKLHALRISHNKLEDIPYDIFNLSNLIELNVGHNKLKQAFYIPRNLEHLYLQNNEIESINVTMICPSPDPVHHHHLTYLRVDQNKLKEPISSYIFFCFPRIHSIYYGEQRSTNGETIQLKTQVFRSYQEEEEEDDHDSQDNTLEGQEVSDEHYNSHYYEMQEWQDTI", "length": 423 }, "evidence": [ { "id": "A0A8V1AAG8", "url": "https://omabrowser.org/oma/group/A0A8V1AAG8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q99983-1", "protein_name": "Osteomodulin", "gene_name": "OMD", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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"MGCLRPIYVLFFCFVVRVYGQYEAYQWDEDYEQEPSEDYEPEFQFHQNIEYGAPFYQNILGCAKECFCPTNFPTSMYCDNRKLKTIPDIPMHIQQLNLQFNDIEAVTADSFINATHLKEINLSHNKIKSQKIDYGVFAKLSNLQQLHLDHNNLEEFPFPLPKSLERLLLGYNEISTLPTHAMDGLVNVTMLDLCYNHLSDSTLKGKILSKLEKLMQLNLCNNRLESMPPGLPLSLMYLSLENNSISSIPEDYFQKLPKLHALRISHNKLEDIPYDIFNLSNLIELNVGHNKLKQAFYIPRNLEHLYLQNNEIQSINVTMMCPSLDPLHHHHLTYLRVDQNKLKEPISSYIFFCFPRIHSIYYGEQRSTNGETIQLKTQVFRRYQDEEEEEEDDSQDHTLEGQEETEEHFNSHYYEMQAWQNTI", "length": 423 }, "evidence": [ { "id": "A0A8V1AAG8", "url": "https://omabrowser.org/oma/group/A0A8V1AAG8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAG8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAG8" } ], "pmid": "" }, { "name": "extracellular matrix", "id": "GO:0031012", 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"database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AAH0", "url": "https://www.orthodb.org/?gene=A0A8V1AAH0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24251", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24251", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24251:SF30", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24251:SF30", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00057", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00057", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00431", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00431", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01392", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01392", "database": "Pfam", "categories": [ "Protein 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"##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052556.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_046759974", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046759974" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAH1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAH1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAH1", "locus": {} } ], "crossref": [ { "id": "A0A8V1AAH1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AAH1", "database": "AlphaFoldDB", "categories": [] }, { "id": "121107573", "url": "https://www.ncbi.nlm.nih.gov/gene/121107573", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003461", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003461", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "SCAIQNT", "url": "https://omabrowser.org/oma/group/SCAIQNT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AAH1", "url": "https://www.orthodb.org/?gene=A0A8V1AAH1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31203", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31203", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31203:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31203:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02422", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02422", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_046759974", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046759974", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AAH1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAH1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AAH1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAH1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSCSSLCAPACGVATPTPLADSCNEPCVRQCPDSTVVIQPPATVVTFPGPILSSFPQNAVVGSAGVPAVGSGLGGTFGRSAGYGGYGGFGGYGGLGGYGGFYGLGGYGGYGGFGSCGYGGWRRGHRYLSGSCGPC", "length": 135, "header": "tr|A0A8V1AAH1-1|A0A8V1AAH1_CHICK Isoform 1 of Keratin OS=Gallus gallus OX=9031 GN= PE=3 SV=1 CANONICAL=A0A8V1AAH1-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AAH1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAH1/entry#A0A8V1AAH1-1", "sequence": { "sequence": "MSCSSLCAPACGVATPTPLADSCNEPCVRQCPDSTVVIQPPATVVTFPGPILSSFPQNAVVGSAGVPAVGSGLGGTFGRSAGYGGYGGFGGYGGLGGYGGFYGLGGYGGYGGFGSCGYGGWRRGHRYLSGSCGPC", "length": 135, "header": "tr|A0A8V1AAH1-1|A0A8V1AAH1_CHICK Isoform 1 of Keratin OS=Gallus gallus OX=9031 GN= PE=3 SV=1 CANONICAL=A0A8V1AAH1-1" }, "locus": { "chromosome": "25", "start_pos": 1582840, "end_pos": 1582436, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069853.1", "url": "https://www.ensembl.org/id/ENSGALT00010069853.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042979.1", "url": "https://www.ensembl.org/id/ENSGALP00010042979.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "structural constituent of cytoskeleton", "id": "GO:0005200", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005200", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAH1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAH1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "intermediate filament", "id": "GO:0005882", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005882", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAH1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAH1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AAI9-1", "uniprot_ac": "A0A8V1AAI9", "uniprot_id": "A0A8V1AAI9_CHICK", "mass": { "chemical_mass": 54441.0, "monoisotopic_mass": 54441.0 }, "refseq": { "ac": "XP_024999581", "name": "interferon regulatory factor 6 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024999581" }, "gene_names": [ { "name": "IRF6", "type": "recommended", "evidence": [ { "id": "A0A8V1AAI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAI9" } ] }, { "name": "IRF6", "type": "synonym", "evidence": [ { "id": "XP_024999581", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024999581" } ] } ], "protein_names": [ { "name": "Interferon regulatory factor 6", "type": "synonym", "evidence": [ { "id": "A0A8V1AAI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAI9/entry#names_and_taxonomy" } ] }, { "name": "interferon regulatory factor 6 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_024999581", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024999581" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052557.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_024999581", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024999581" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAI9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAI9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "IRF6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAI9", "locus": { "chromosome": "26", "start_pos": 3202425, "end_pos": 3209902, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027212", "url": "https://www.ensembl.org/id/ENSGALG00010027212" } ] } } ], "crossref": [ { "id": "A0A8V1AAI9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AAI9", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00103", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00103", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "419863", "url": "https://www.ncbi.nlm.nih.gov/gene/419863", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001346", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001346", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008984", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008984", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017855", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017855", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019471", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019471", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019817", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019817", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036388", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036388", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036390", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036390", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "NEAWPKE", "url": "https://omabrowser.org/oma/group/NEAWPKE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AAI9", "url": "https://www.orthodb.org/?gene=A0A8V1AAI9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ADB9", "url": "https://www.orthodb.org/?gene=A0A8V1ADB9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11949", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11949", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11949:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11949:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00605", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00605", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF10401", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10401", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_024999581", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024999581", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AAI9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAI9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AAI9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAI9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ADB9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADB9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ADB9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADB9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLGDAAGSETMALHPRRVRLKPWLVAQVDSGMYPGLIWLNREAKRFQIPWKHATRHSPQHEEENTIFKAWAVETGKYQEGVDEPDPAKWKAQLRCALNKSREFNLMYDGTKEVPMNPVKIYEVCDIPQSQGSIINPGSTGSAPWDEKENDLDEDEEEELNPSQHVPIQETFPFLNINGKSHFPSVDSPMAPASAENCSPEAVWPKNEPLDMEMPPTALQHDFFSSPELWISSLPMTDLEIKFEYRGKETGQTTTVSNPQGCRLFYGELGPMPDQEELFGPINLEQVRFPGTEQITNEKQKIFTSRLLDVMDRGLILEVSGHAIYAVRLCQCKVYWSGPCAPSATTPNLIERQKKVKLFCLETFLSELIAHQKGQIEKQPPFEIYFCFGEEWPDGKPRERKLIVVQVIPVVARMIYEMFSGDFTRSFDSGSVRLQISTPDIKDNIVAHLKQLYRLLQTHQEGWPMQAPTMHMAQPLPAQ", "length": 478, "header": "tr|A0A8V1AAI9-1|A0A8V1AAI9_CHICK Isoform 1 of Interferon regulatory factor 6 OS=Gallus gallus OX=9031 GN=IRF6 PE=1 SV=1 CANONICAL=A0A8V1AAI9-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AAI9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAI9/entry#A0A8V1AAI9-1", "sequence": { "sequence": "MLGDAAGSETMALHPRRVRLKPWLVAQVDSGMYPGLIWLNREAKRFQIPWKHATRHSPQHEEENTIFKAWAVETGKYQEGVDEPDPAKWKAQLRCALNKSREFNLMYDGTKEVPMNPVKIYEVCDIPQSQGSIINPGSTGSAPWDEKENDLDEDEEEELNPSQHVPIQETFPFLNINGKSHFPSVDSPMAPASAENCSPEAVWPKNEPLDMEMPPTALQHDFFSSPELWISSLPMTDLEIKFEYRGKETGQTTTVSNPQGCRLFYGELGPMPDQEELFGPINLEQVRFPGTEQITNEKQKIFTSRLLDVMDRGLILEVSGHAIYAVRLCQCKVYWSGPCAPSATTPNLIERQKKVKLFCLETFLSELIAHQKGQIEKQPPFEIYFCFGEEWPDGKPRERKLIVVQVIPVVARMIYEMFSGDFTRSFDSGSVRLQISTPDIKDNIVAHLKQLYRLLQTHQEGWPMQAPTMHMAQPLPAQ", "length": 478, "header": "tr|A0A8V1AAI9-1|A0A8V1AAI9_CHICK Isoform 1 of Interferon regulatory factor 6 OS=Gallus gallus OX=9031 GN=IRF6 PE=1 SV=1 CANONICAL=A0A8V1AAI9-1" }, "locus": { "chromosome": "26", "start_pos": 3209890, "end_pos": 3202776, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065974.1", "url": "https://www.ensembl.org/id/ENSGALT00010065974.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040240.1", "url": "https://www.ensembl.org/id/ENSGALP00010040240.1" } ] } }, { "isoform_ac": "A0A8V1ADB9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAI9/entry#A0A8V1ADB9-1", "sequence": { "sequence": "MALHPRRVRLKPWLVAQVDSGMYPGLIWLNREAKRFQIPWKHATRHSPQHEEENTIFKAWAVETGKYQEGVDEPDPAKWKAQLRCALNKSREFNLMYDGTKEVPMNPVKIYEVCDIPQSQGSIINPGSTGSAPWDEKENDLDEDEEEELNPSQHVPIQETFPFLNINGKSHFPSVDSPMAPASAENCSPEAVWPKNEPLDMEMPPTALQHDFFSSPELWISSLPMTDLEIKFEYRGKETGQTTTVSNPQGCRLFYGELGPMPDQEELFGPINLEQVRFPGTEQITNEKQKIFTSRLLDVMDRGLILEVSGHAIYAVRLCQCKVYWSGPCAPSATTPNLIERQKKVKLFCLETFLSELIAHQKGQIEKQPPFEIYFCFGEEWPDGKPRERKLIVVQVIPVVARMIYEMFSGDFTRSFDSGSVRLQISTPDIKDNIVAHLKQLYRLLQTHQEGWPMQAPTMHMAQPLPAQ", "length": 468, "header": "tr|A0A8V1ADB9-1|A0A8V1ADB9_CHICK Computationally mapped isoform of Interferon regulatory factor 6 OS=Gallus gallus OX=9031 GN=IRF6 PE=1 SV=1 CANONICAL=A0A8V1AAI9-1" }, "locus": { "chromosome": "26", "start_pos": 3206234, "end_pos": 3202776, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065973.1", "url": "https://www.ensembl.org/id/ENSGALT00010065973.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040239.1", "url": "https://www.ensembl.org/id/ENSGALP00010040239.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "D4AAV0-1", "protein_name": "Interferon regulatory factor 6", "gene_name": "Irf6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALHPRRVRLKPWLVAQVDSGLYPGLIWLHRDSKRFQIPWKHATRHSPQQEEENTIFKAWAVETGKYQEGVDDPDPAKWKAQLRCALNKSREFNLMYDGTKEVPMNPVKIYQVCDIPQPQGSVINPGSTGSAPWDEKDNDVDEDDEEDELEQSQHHVPIQDTFPFLNINGSPMAPASVGNCSVGNCSPESVWPKTEPLEMEVPQAPIQPFYSSPELWISSLPMTDLDIKFQYRGKEYGQTMTVSNPQGCRLFYGDLGPMPDQEELFGPVSLEQVKFPGPEHITNEKQKLFTSKLLDVMDRGLILEVSGHAIYAIRLCQCKVYWSGPCAPSLAAPNLIERQKKVKLFCLETFLSELIAHQKGQIEKQPPFEIYLCFGEEWPDGKPLERKLILVQVIPVVARMIYEMFSGDFTRSFDSGSVRLQISTPDIKDNIVAQLKQLYRILQTQESWQPMQPAPSMQLPPALPAQ", "length": 467 }, "evidence": [ { "id": "A0A8V1AAI9", "url": "https://omabrowser.org/oma/group/A0A8V1AAI9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E9LK28-1", "protein_name": "Interferon regulatory factor 6", "gene_name": "IRF6", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MALHPRRVRLKPWLVAQVDSGLYPGLIWLHRDSKRFQIPWKHATRHSPQQEEENTIFKAWAVETGKYQEGVDDPDPAKWKAQLRCALNKSREFNLMYDGTKEVPMNPVKIYQVCDIPQPQGSVVNPGSTGSAPWDEKDNDVDDEDEEDELDQSQHHVPIQDTFPFLNINGSPIAPASVGNCSVGNCSPEAVWPKTEPLEMEVPQAPIQPFYSSPELWISSLPMTDLDIKFQYRGKEYGQTMTVSNPQGCRLFYGDLGPMPDQEELFGPVSLEQVKFPGPEHITNEKQKLFTSKLLDVMDRGLILEVSGHAIYAIRLCQCKVYWSGPCAPSLVAPNLIERQKKVKLFCLETFLSDLIAHQKGQIEKQPPFEIYLCFGEEWPDGKPLERKLILVQVIPVVARMIYEMFSGDFTRSFDSGSVRLQISTPDIKDNIVAQLKQLYRILQTQESWQPMQPTPSMQMPPALPAQ", "length": 467 }, "evidence": [ { "id": "A0A8V1AAI9", "url": "https://omabrowser.org/oma/group/A0A8V1AAI9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3H2M3-1", "protein_name": "Interferon regulatory factor 6", "gene_name": "Irf6", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MALHPRRVRLKPWLVAQVDSGLYPGLIWLHRDSKRFQIPWKHATRHSPQQEEENTIFKAWAVETGKYQEGVDDPDPAKWKAQLRCALNKSREFNLMYDGTKEVPMNPVKIYQVCDIPQPQGSVINPGSTGSAPWDEKDNDVDEDEEEDELDQSQHHVPIQDTFPFLNISGSPMAPASVGNCSVGNCSPESVWTKTEPLEMEVPQAPIQPFHSSPELWISSLPMTDLDIKFQYRGKEYGQTMTVSNPQGCRLFYGDLGPMPDQEELFGPVSLEQVKFPGPEHITNEKQKLFTSKLLDVMDRGLILEVSGHAIYAIRLCQCKVYWSGPCAPSLAAPNLIERQKKVKLFCLETFLSELIAHQKGQIEKQPPFEIYLCFGEEWPDGKPPERKLILVQVIPVVARMIYEMFSGDFTRSFDSGSVRLQISTPDIKDNIVAQLKQLYRILQTQESWQPMQPAPSMQLPPALPAQ", "length": 467 }, "evidence": [ { "id": "A0A8V1AAI9", "url": "https://omabrowser.org/oma/group/A0A8V1AAI9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "O14896-1", "protein_name": "Interferon regulatory factor 6", "gene_name": "IRF6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MALHPRRVRLKPWLVAQVDSGLYPGLIWLHRDSKRFQIPWKHATRHSPQQEEENTIFKAWAVETGKYQEGVDDPDPAKWKAQLRCALNKSREFNLMYDGTKEVPMNPVKIYQVCDIPQPQGSIINPGSTGSAPWDEKDNDVDEEDEEDELDQSQHHVPIQDTFPFLNINGSPMAPASVGNCSVGNCSPEAVWPKTEPLEMEVPQAPIQPFYSSPELWISSLPMTDLDIKFQYRGKEYGQTMTVSNPQGCRLFYGDLGPMPDQEELFGPVSLEQVKFPGPEHITNEKQKLFTSKLLDVMDRGLILEVSGHAIYAIRLCQCKVYWSGPCAPSLVAPNLIERQKKVKLFCLETFLSDLIAHQKGQIEKQPPFEIYLCFGEEWPDGKPLERKLILVQVIPVVARMIYEMFSGDFTRSFDSGSVRLQISTPDIKDNIVAQLKQLYRILQTQESWQPMQPTPSMQLPPALPPQ", "length": 467 }, "evidence": [ { "id": "A0A8V1AAI9", "url": "https://omabrowser.org/oma/group/A0A8V1AAI9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P97431-1", "protein_name": "Interferon regulatory factor 6", "gene_name": "Irf6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALHPRRVRLKPWLVAQVDSGLYPGLIWLHRDSKRFQIPWKHATRHSPQQEEENTIFKAWAVETGKYQEGVDDPDPAKWKAQLRCALNKSREFNLMYDGTKEVPMNPVKIYQVCDIPQTQGSVINPGSTGSAPWDEKDNDVDEDEEEDELEQSQHHVPIQDTFPFLNINGSPMAPASVGNCSVGNCSPESVWPKTEPLEMEVPQAPIQPFYSSPELWISSLPMTDLDIKFQYRGKEYGQTMTVSNPQGCRLFYGDLGPMPDQEELFGPVSLEQVKFPGPEHITNEKQKLFTSKLLDVMDRGLILEVSGHAIYAIRLCQCKVYWSGPCAPSLAAPNLIERQKKVKLFCLETFLSELIAHQKGQIEKQPPFEIYLCFGEEWPDGKPLERKLILVQVIPVVARMIYEMFSGDFTRSFDSGSVRLQISTPDIKDNIVAQLKQLYRILQTQESWQPMQPAPSMQLPQALPAQ", "length": 467 }, "evidence": [ { "id": "A0A8V1AAI9", "url": "https://omabrowser.org/oma/group/A0A8V1AAI9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6PGZ7-1", "protein_name": "Interferon regulatory factor 6", "gene_name": "irf6", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSSHPRRVRLKPWLVSQVDNATFPGLVWLDRDAKRFQIPWKHATRHTPQQEEENTIFKAWAVETGKYQEGVDEPDPAKWKAQLRCALNKSREFNLIYDGTKEVPMNPLKIYDVCDIPQTPSNPGSVPTYETDGDEDDIPDTPEPPPPYASHGMSASPLAAVWTPPGSVSPLQPSSCAPPPALPPPPALPPPAATVLPAAAAPPANVWPKKEPEDVEMQPPPMEIQTPTALDNLFITPETWISSLPMTDLEVQFYYRGKEVCPPLTVSNPQGCRLFYGDLGPIVNQEELFGPVSLEQVRFPPTEHIANDKQRVFTSRLLDVMDRGLILEVSGHDIYAVRLCQCKVYWSGPCAPNPNAPNLIERQQKVKLFCLESFLSGVITHQRGQSSDAPLYDIHLCFGEEWPDGRPRERKLIMVQVVPVVARMISEMFSGDCTRSFDSGSVRLQISIPDIKDNIVTHLKQLYRLLQTHQGPENWPLPPGAALQLSSALHTQ", "length": 492 }, "evidence": [ { "id": "A0A8V1AAI9", "url": "https://omabrowser.org/oma/group/A0A8V1AAI9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAI9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAI9" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAI9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAI9" } ], "pmid": "" }, { "name": "apical part of cell", "id": "GO:0045177", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045177", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAI9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAI9" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAI9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAI9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAI9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAI9" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAI9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAI9" } ], "pmid": "" }, { "name": "negative regulation of cell population proliferation", "id": "GO:0008285", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008285", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAI9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAI9" } ], "pmid": "" }, { "name": "immune system process", "id": "GO:0002376", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002376", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAI9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAI9" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAI9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAI9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAI9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAI9" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAI9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAI9" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAI9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAI9" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAI9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAI9" } ], "pmid": "" }, { "name": "transcription cis-regulatory region binding", "id": "GO:0000976", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000976", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAI9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAI9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 196, "end_pos": 198, "annotation": "n_glycosylation_sequon" }, { "start_pos": 98, "end_pos": 100, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": 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"glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", 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}, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AAK0-1", "uniprot_ac": "A0A8V1AAK0", "uniprot_id": "A0A8V1AAK0_CHICK", "mass": { "chemical_mass": 102925.0, "monoisotopic_mass": 102925.0 }, "refseq": {}, "gene_names": [ { "name": "ANKRD24", "type": "recommended", "evidence": [ { "id": "A0A8V1AAK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAK0" } ] } ], "protein_names": [ { "name": "Ankyrin repeat domain 24", "type": "synonym", "evidence": [ { "id": "A0A8V1AAK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAK0/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAK0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAK0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ANKRD24", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAK0", "locus": { "chromosome": "28", "start_pos": 3027588, "end_pos": 3033768, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027220", "url": "https://www.ensembl.org/id/ENSGALG00010027220" } ] } } ], "crossref": [ { "id": "A0A8V1AAK0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AAK0", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR002110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042420", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042420", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AAK0", "url": "https://www.orthodb.org/?gene=A0A8V1AAK0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24129", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24129", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24129:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24129:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00023", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00023", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12796", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12796", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13857", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13857", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1AAK0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAK0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AAK0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAK0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": 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} ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AAP5-1", "uniprot_ac": "A0A8V1AAP5", "uniprot_id": "A0A8V1AAP5_CHICK", "mass": { "chemical_mass": 78164.0, "monoisotopic_mass": 78164.0 }, "refseq": { "ac": "XP_040508871", "name": "leucine-rich repeat neuronal protein 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040508871" }, "gene_names": [ { "name": "LRRN2", "type": "recommended", "evidence": [ { "id": "A0A8V1AAP5", "database": 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Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052557.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040508871", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040508871" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAP5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAP5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LRRN2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAP5", "locus": { "chromosome": "26", "start_pos": 1864852, "end_pos": 1897195, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027241", "url": "https://www.ensembl.org/id/ENSGALG00010027241" } ] } } ], "crossref": [ { "id": "428261", "url": "https://www.ncbi.nlm.nih.gov/gene/428261", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000483", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000483", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003591", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003591", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013098", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013098", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050541", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050541", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:428261", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428261", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LPAWAFW", "url": "https://omabrowser.org/oma/group/LPAWAFW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AAP5", "url": "https://www.orthodb.org/?gene=A0A8V1AAP5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24369", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24369", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24369:SF211", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24369:SF211", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07679", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07679", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13855", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13855", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040508871", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040508871", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AAP5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAP5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AAP5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAP5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRGFQGSSLLLCIVAAAAIPIVPWKVKCPLQCVCQIRPWYTPRSVYREAATVDCNDLFITAVPEDLPAGTQTLLLQSNNIARLEQSELDYLRNLTELDLSQNSFSNVWDFGLKSMPQLLSLHLEENRLTELPDSSFPGLGSLQELYLNHNQLRRIAPRAFAGLGSLLRLHLNSNLLQMVDSRWFQMLPSLEILMIGGNRVDAILDMNFRPLSNLRSLVLAGMNLQEISDYALEGLRSLESLSFYDNKLVTVPKRALQRVPSLKFLDLNKNPLQRVRQSDFTNMLHLKELGLNNMEELVSIDKFALINLPELTKLDVTNNPKLSFIHPNAFHHLPQMETLMLNNNALSALHKQTVESLPNLQEISIHSNPIRCDCVIRWVNSTEMRIRFIEPQSTLCAEPPDLKRRHIRDVPFREMTDRCLPLISTQSFPSRLEVMDGDNISLHCRAMAEPDPEIYWVTPSGVKLIPYAHDGHYKVHPEGTLEIMGISAHEAGLYTCVAHNLLGADTKSITVLVNSSFPHSEASLELAVLDVQPYHILLAWKPHLNAVSSNLTWSSFLLSSSLDTTNVARIPLGTHAYNITRLHQDTEYWACLHVAFVDLQAKVACINARTKEAIRHHRFLGDRQCLLTLLALSILLLATGLVARCGFGDEPRRAGDALWDAGAVRVVYPHLAQHWAQGPRSGQLLAVEVQAAPLDS", "length": 696, "header": "tr|A0A8V1AAP5-1|A0A8V1AAP5_CHICK Isoform 1 of Leucine rich repeat neuronal 2 OS=Gallus gallus OX=9031 GN=LRRN2 PE=4 SV=1 CANONICAL=A0A8V1AAP5-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AAP5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAP5/entry#A0A8V1AAP5-1", "sequence": { "sequence": "MRGFQGSSLLLCIVAAAAIPIVPWKVKCPLQCVCQIRPWYTPRSVYREAATVDCNDLFITAVPEDLPAGTQTLLLQSNNIARLEQSELDYLRNLTELDLSQNSFSNVWDFGLKSMPQLLSLHLEENRLTELPDSSFPGLGSLQELYLNHNQLRRIAPRAFAGLGSLLRLHLNSNLLQMVDSRWFQMLPSLEILMIGGNRVDAILDMNFRPLSNLRSLVLAGMNLQEISDYALEGLRSLESLSFYDNKLVTVPKRALQRVPSLKFLDLNKNPLQRVRQSDFTNMLHLKELGLNNMEELVSIDKFALINLPELTKLDVTNNPKLSFIHPNAFHHLPQMETLMLNNNALSALHKQTVESLPNLQEISIHSNPIRCDCVIRWVNSTEMRIRFIEPQSTLCAEPPDLKRRHIRDVPFREMTDRCLPLISTQSFPSRLEVMDGDNISLHCRAMAEPDPEIYWVTPSGVKLIPYAHDGHYKVHPEGTLEIMGISAHEAGLYTCVAHNLLGADTKSITVLVNSSFPHSEASLELAVLDVQPYHILLAWKPHLNAVSSNLTWSSFLLSSSLDTTNVARIPLGTHAYNITRLHQDTEYWACLHVAFVDLQAKVACINARTKEAIRHHRFLGDRQCLLTLLALSILLLATGLVARCGFGDEPRRAGDALWDAGAVRVVYPHLAQHWAQGPRSGQLLAVEVQAAPLDS", "length": 696, "header": "tr|A0A8V1AAP5-1|A0A8V1AAP5_CHICK Isoform 1 of Leucine rich repeat neuronal 2 OS=Gallus gallus OX=9031 GN=LRRN2 PE=4 SV=1 CANONICAL=A0A8V1AAP5-1" }, "locus": { "chromosome": "26", "start_pos": 1867726, "end_pos": 1865639, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066042.1", "url": "https://www.ensembl.org/id/ENSGALT00010066042.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040308.1", "url": "https://www.ensembl.org/id/ENSGALP00010040308.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 458, "start_aa": "Thr", "end_pos": 458, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr458", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:428261", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428261", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZAV8-1", "protein_name": "Leucine rich repeat neuronal 2", "gene_name": "Lrrn2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRLLVAALLLSWAASTNTAVPVVPWRVPCPPQCACQIRPWYTPRSSYREATTVDCNDLFLTAVPPGLPAGTQTLLLQSNSISRIEQTELGYLANLTELDLSQNSFSDARDCDFQALPQLLSLHLEENQLSRLEDHSFAGLTRLQELYLNHNQLCRISPRAFEGLGNLLRLHLNSNLLRTIDSRWFEMLPNLEILMIGGNKVDAILDMNFRPLANLRSLVLAGMSLREISDYALEGLQSLESLSFYDNQLAQVPKRALEQVPGLKFLDLNKNPLQRVGPGDFANMLHLKELGLNNMEELVSIDKFALVNLPELTKLDITNNPRLSFIHPRAFHHLPQMETLMLNNNALSALHQQTVESLPNLQEVGLHGNPIRCDCVIRWANATGTHVRFIEPQSTLCAEPPDLQRRPVREVPFREMTDHCLPLISPRSFPSSLQVASGESLVLHCRALAEPEPEIYWVTPAGVRLTPARSGRKYRVFPEGTLELRRVTAEEAGLYTCVAQNLVGADTKTVSVVVGHAPFQPGRDKGPGLELHVQETHPYHILLFWAPPPNIVSTNLTWSSAASLRDHETTALARLPRGTHRYNITRLLPATEYWACLQVAFADAHTQLACVWARTKEASPCHRALGDRPGLIAILALAVLLLAAGLAAHLGRGQSKQRVGEKPLLPVWAFWGWSAPSVRVVSAPIVLPWNPGRKQPRCQMGKQCHHHCLNIAEAPPGLSSREITRTTLHQTGRDLGQMPARNAALIDPHA", "length": 750 }, "evidence": [ { "id": "A0A8V1AAP5", "url": "https://omabrowser.org/oma/group/A0A8V1AAP5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1S362-1", "protein_name": "Leucine rich repeat neuronal 2", "gene_name": "LRRN2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRLLVAPLLLAWVAGATAAVPVVPWRVPCPPQCACQIRPWYTPRSSYREATTVDCNDLFLTAVPPALPAGTQTLLLQSNSIVRVDQGELGYLANLTELDLSQNSFSDTRDCDFRALPQLLSLHLEENQLTRLEDHSFAGLASLQELYLNHNQLYRIAPRAFAGLSNLLRLHLNSNLLRAVDSRWFEMLPNLEILMIGGNRVDAILDMNFRPLANLRSLVLAGMNLREISDYALEGLQSLESLSFYDNRLARVPRRALEQVPGLKFLDLNKNPLQRVGPGDFANMLHLKELGLNNMEELVSIDKFALVNLPELTKLDITNNPRLSFIHPRAFHHLPQMETLMLNNNALSALHQQTVESLPNLQEVGLHGNPIRCDCVIRWANATGTRVRFIEPQSTLCAEPPDLQRRPVREVPFREMTDHCLPLISPRSFPSSLQVASGESLVLHCRALAEPEPEIYWVTPAGVRLTAARAGRKYRVYPEGTLELRRVTVEEAGLYTCVAQNLVGADTKTVSVVVGRAPLQPGRDKGWGLELRVQETHPYHILLSWVSPPNTVSTNLTWSSASALRGHGATALARLPRGTHSYNITRLLQATEYWACLQVAFADAHTQLACVWARTKEATPCHRALGDRPGLIAVLALAILLLAAGLAAHLGTGQPRQGVSGRPLLPVWAFWGWSASSVRVVSAPLVLHWNPGRKPPRSSEEETLSPPLSQNS", "length": 712 }, "evidence": [ { "id": "A0A8V1AAP5", "url": "https://omabrowser.org/oma/group/A0A8V1AAP5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O75325-1", "protein_name": "Leucine-rich repeat neuronal protein 2", "gene_name": "LRRN2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRLLVAPLLLAWVAGATAAVPVVPWHVPCPPQCACQIRPWYTPRSSYREATTVDCNDLFLTAVPPALPAGTQTLLLQSNSIVRVDQSELGYLANLTELDLSQNSFSDARDCDFHALPQLLSLHLEENQLTRLEDHSFAGLASLQELYLNHNQLYRIAPRAFSGLSNLLRLHLNSNLLRAIDSRWFEMLPNLEILMIGGNKVDAILDMNFRPLANLRSLVLAGMNLREISDYALEGLQSLESLSFYDNQLARVPRRALEQVPGLKFLDLNKNPLQRVGPGDFANMLHLKELGLNNMEELVSIDKFALVNLPELTKLDITNNPRLSFIHPRAFHHLPQMETLMLNNNALSALHQQTVESLPNLQEVGLHGNPIRCDCVIRWANATGTRVRFIEPQSTLCAEPPDLQRLPVREVPFREMTDHCLPLISPRSFPPSLQVASGESMVLHCRALAEPEPEIYWVTPAGLRLTPAHAGRRYRVYPEGTLELRRVTAEEAGLYTCVAQNLVGADTKTVSVVVGRALLQPGRDEGQGLELRVQETHPYHILLSWVTPPNTVSTNLTWSSASSLRGQGATALARLPRGTHSYNITRLLQATEYWACLQVAFADAHTQLACVWARTKEATSCHRALGDRPGLIAILALAVLLLAAGLAAHLGTGQPRKGVGGRRPLPPAWAFWGWSAPSVRVVSAPLVLPWNPGRKLPRSSEGETLLPPLSQNS", "length": 713 }, "evidence": [ { "id": "A0A8V1AAP5", "url": "https://omabrowser.org/oma/group/A0A8V1AAP5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAP5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAP5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "signaling receptor activity", "id": "GO:0038023", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038023", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAP5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAP5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 380, "end_pos": 382, "annotation": "n_glycosylation_sequon" }, { "start_pos": 439, "end_pos": 441, "annotation": "n_glycosylation_sequon" }, { "start_pos": 514, "end_pos": 516, "annotation": "n_glycosylation_sequon" }, { "start_pos": 550, "end_pos": 552, "annotation": "n_glycosylation_sequon" }, { "start_pos": 578, "end_pos": 580, "annotation": "n_glycosylation_sequon" }, { "start_pos": 93, "end_pos": 95, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AAP5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAP5" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 421, "end_pos": 510, "start_aa": "Pro", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 458 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 380, "end_pos": 382 }, { "start_pos": 439, "end_pos": 441 }, { "start_pos": 514, "end_pos": 516 }, { "start_pos": 550, "end_pos": 552 }, { "start_pos": 578, "end_pos": 580 }, { "start_pos": 93, "end_pos": 95 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], 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"exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AC45-1", "uniprot_ac": "A0A8V1AC45", "uniprot_id": "A0A8V1AC45_CHICK", "mass": { "chemical_mass": 32630.0, "monoisotopic_mass": 32630.0 }, "refseq": {}, "gene_names": [ { "name": "GOSR2", "type": "recommended", "evidence": [ { "id": "A0A8V1AC45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC45" } ] } ], "protein_names": [ { "name": "Golgi SNAP receptor complex member 2", "type": "synonym", "evidence": [ { "id": "A0A8V1AC45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC45/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Involved in transport of proteins from the cis/medial-Golgi to the trans-Golgi network.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9S7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9S7#function" }, { "database": "UniProtKB", "id": "ARBA00037078", "url": "https://www.uniprot.org/uniprotkb/ARBA00037078#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AC45", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC45" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "GOSR2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC45", "locus": { "chromosome": "27", "start_pos": 693596, "end_pos": 705907, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010025936", "url": "https://www.ensembl.org/id/ENSGALG00010025936" } ] } } ], "crossref": [ { "id": "A0A8V1AC45", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AC45", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15863", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15863", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "419973", "url": "https://www.ncbi.nlm.nih.gov/gene/419973", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR027027", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027027", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038407", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038407", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR060290", "url": "https://www.ebi.ac.uk/interpro/entry/IPR060290", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "LKYDSRH", "url": "https://omabrowser.org/oma/group/LKYDSRH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A9S7", "url": "https://www.orthodb.org/?gene=A0A8V1A9S7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AC45", "url": "https://www.orthodb.org/?gene=A0A8V1AC45", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21230", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21230", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21230:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21230:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12352", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12352", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF27021", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27021", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-204005", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-204005", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5694530", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5694530", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-6811438", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6811438", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1A9S7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9S7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A9S7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9S7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AC45", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC45", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AC45-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC45-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSSPQALEGCTEVSPGPPLLQACSDEWPWVGMGQWLAQMILEVVPNLNDPATLPFSHLGPKTRSTHRLREALPPAAPQTQRRDLAGPRPAEAEVASYGSGSCVRRKRRRRVGRKGGGRAAEMEGLYHQTNKQVHEVQSYMGRLETSDKESVHLVENEIQARIDKVFSNLERLEILSSKEPPNKRQNAKLRVDQLKYDVQHLQTALRNFQHRRYIREQQERQREELLARTFTTNGTQKKILDVANTLGLSNTVMRLIEKRAFQDKYFMIGGMIVTCVIMFLVVQYLT", "length": 286, "header": "tr|A0A8V1AC45-1|A0A8V1AC45_CHICK Isoform 1 of Golgi SNAP receptor complex member 2 OS=Gallus gallus OX=9031 GN=GOSR2 PE=1 SV=1 CANONICAL=A0A8V1AC45-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A9S7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC45/entry#A0A8V1A9S7-1", "sequence": { "sequence": "MGRLETSDKESVHLVENEIQARIDKVFSNLERLEILSSKEPPNKRQNAKLRVDQLKYDVQHLQTALRNFQHRRYIREQQERQREELLARTFTTNDSDTTIPIDETLQFNESLQNAHRGMDDLIGSGTNILQGLRDQRVTLKGTQKKILDVANTLGLSNTVMRLIEKRAFQDKYFMIGGMIVTCVIMFLVVQYLT", "length": 194, "header": "tr|A0A8V1A9S7-1|A0A8V1AC45_CHICK Computationally mapped isoform of Golgi SNAP receptor complex member 2 OS=Gallus gallus OX=9031 GN=GOSR2 PE=1 SV=1 CANONICAL=A0A8V1AC45-1" }, "locus": { "chromosome": "27", "start_pos": 703337, "end_pos": 696613, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063225.1", "url": "https://www.ensembl.org/id/ENSGALT00010063225.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039027.1", "url": "https://www.ensembl.org/id/ENSGALP00010039027.1" } ] } }, { "isoform_ac": "A0A8V1AC45-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC45/entry#A0A8V1AC45-1", "sequence": { "sequence": "MSSPQALEGCTEVSPGPPLLQACSDEWPWVGMGQWLAQMILEVVPNLNDPATLPFSHLGPKTRSTHRLREALPPAAPQTQRRDLAGPRPAEAEVASYGSGSCVRRKRRRRVGRKGGGRAAEMEGLYHQTNKQVHEVQSYMGRLETSDKESVHLVENEIQARIDKVFSNLERLEILSSKEPPNKRQNAKLRVDQLKYDVQHLQTALRNFQHRRYIREQQERQREELLARTFTTNGTQKKILDVANTLGLSNTVMRLIEKRAFQDKYFMIGGMIVTCVIMFLVVQYLT", "length": 286, "header": "tr|A0A8V1AC45-1|A0A8V1AC45_CHICK Isoform 1 of Golgi SNAP receptor complex member 2 OS=Gallus gallus OX=9031 GN=GOSR2 PE=1 SV=1 CANONICAL=A0A8V1AC45-1" }, "locus": { "chromosome": "27", "start_pos": 705708, "end_pos": 696613, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063233.1", "url": "https://www.ensembl.org/id/ENSGALT00010063233.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039035.1", "url": "https://www.ensembl.org/id/ENSGALP00010039035.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-204005", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-204005", "resource": "Reactome", "description": "COPII-mediated vesicle transport" }, { "id": "R-GGA-5694530", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5694530", "resource": "Reactome", "description": "Cargo concentration in the ER" }, { "id": "R-GGA-6811438", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6811438", "resource": "Reactome", "description": "Intra-Golgi traffic" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287BIC8-1", "protein_name": "Golgi SNAP receptor complex member 2", "gene_name": "GOSR2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEPLYQQTHKQVHEIQSHMGRLETADKQSVHLVENEIQASIDQIFSHLERLEILSSKEPPNKRQNAKLRVDQLKYDVQHLQTALRNFQQRRYTREQQERQREELLSRTFTTNDSDTTIPMDESLQFNSSLQKIHHGMDDLIGGGHSILEGLRAQRLTLKGTQKKILDIANMLGLSNTVMRLIEKRAFQDKYFMIGGMLLTCVVMFLAVQYLT", "length": 212 }, "evidence": [ { "id": "A0A8V1AC45", "url": "https://omabrowser.org/oma/group/A0A8V1AC45/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O14653-1", "protein_name": "Golgi SNAP receptor complex member 2", "gene_name": "GOSR2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDPLFQQTHKQVHEIQSCMGRLETADKQSVHIVENEIQASIDQIFSRLERLEILSSKEPPNKRQNARLRVDQLKYDVQHLQTALRNFQHRRHAREQQERQREELLSRTFTTNDSDTTIPMDESLQFNSSLQKVHNGMDDLILDGHNILDGLRTQRLTLKGTQKKILDIANMLGLSNTVMRLIEKRAFQDKYFMIGGMLLTCVVMFLVVQYLT", "length": 212 }, "evidence": [ { "id": "A0A8V1AC45", "url": "https://omabrowser.org/oma/group/A0A8V1AC45/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "O35165-1", "protein_name": "Golgi SNAP receptor complex member 2", "gene_name": "Gosr2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEPLYQQTHKQVHEIQSHMGRLETADKQSVHLVENEIQASIDQIFSHLERLEILSSKEPPNRRQNAKLRVDQLKYDVQHLQTALRNFQHRRQAKEQQERQRDELLSRTFTTNDSDTTIPMDESLQFNSSLQNIHHGMDDLIGGGHSILEGLRAQRLTLKGTQKKILDIANMLGLSNTVMRLIEKRAFQDKYFMIGGMLLTCAVMFLVVQYLT", "length": 212 }, "evidence": [ { "id": "A0A8V1AC45", "url": "https://omabrowser.org/oma/group/A0A8V1AC45/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O35166-1", "protein_name": "Golgi SNAP receptor complex member 2", "gene_name": "Gosr2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEPLYQQTNKQVQEIQSHMGRLERADKQSVHLVENEIQASIEQIFSHLERLEILSSKEPLNRRQNAKLRVDQLKYDVQHLQTALRNFQHRRQVREQQERQRDELLSRTFTTNDSDTTIPMDESLQFNSSLHNIHHGMDDLIGGGHSILEGLRAQRLTLKGTQKKILDIANMLGLSNTVMRLIEKRAFQDKYFMIGGMLLTCAVMFLVVQYLT", "length": 212 }, "evidence": [ { "id": "A0A8V1AC45", "url": "https://omabrowser.org/oma/group/A0A8V1AC45/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q55FD0-1", "protein_name": "V-SNARE family protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MYSNDSGNGYGYGYSTNSSSSSNNISSISNLQHRDTSNRDNGSGSSSGSGLDDLYKQANKLLFSIRNDLETLETGTDTSVIIQSKLSTNINQLSRLSDQIDGMVSNEPIAKREIWRILLIIIKKLKNFRKVKQLVEESKSLRKSLDMFLQTKYKKQMEEEEKNKLMGRRKAGESSAIGNLMKENKHLNDGNSTLDSLTEMGNSIIYNLVGQNSKLKGVNKKIYDIANTLGLSRSVIQRIKRRQHQDKVIVYSGMVIVLIIVFLLWYFFRK", "length": 270 }, "evidence": [ { "id": "A0A8V1AC45", "url": "https://omabrowser.org/oma/group/A0A8V1AC45/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9SJL6-1", "protein_name": "Membrin-11", "gene_name": "MEMB11", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MASGIVEGGGSLSDVYSSAKRILLKARDGIERLERFESSSMDSPDLASSVKRDITEVRSLCSNMDTLWRSIPVKSQRDLWRRKTEQVGEEAEYLNLSLEKYMSRNQRKMLEAKERADLLGRASGEGAHILQIFDEEAQAMSSVKNSKRMLEESFSSGVAILSKYAEQRDRLKSAQRKALDVLNTVGLSNSVLRLIERRNRVDTWIKYAGMIATLVILYLFIRWTR", "length": 225 }, "evidence": [ { "id": "A0A8V1AC45", "url": "https://omabrowser.org/oma/group/A0A8V1AC45/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9VRL2-1", "protein_name": "Probable Golgi SNAP receptor complex member 2", "gene_name": "Membrin", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MESLYHQTNNVVKDIERDFQRLSQLSAQESLDVENGIQLKITQANANCDRLDVLLYKVPPSQRQSSKLRVDQLKYDLRHLQTSLQTARERRQRRMQEISEREQLLNHRFTANSAQPEETRLQLDYELQHHTQLGNAHRGVDDMIASGSGILESLISQRMTLGGAHKRIQAIGSTLGLSNHTMKLIERRLVEDRRIFIGGVVVTLLIIALIIYFLVL", "length": 216 }, "evidence": [ { "id": "A0A8V1AC45", "url": "https://omabrowser.org/oma/group/A0A8V1AC45/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AC45", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC45" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AC45", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC45" } ], "pmid": "" }, { "name": "late endosome membrane", "id": "GO:0031902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031902", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AC45", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC45" } ], "pmid": "" }, { "name": "ER to Golgi transport vesicle membrane", "id": "GO:0012507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012507", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AC45", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC45" } ], "pmid": "" }, { "name": "SNARE complex", "id": "GO:0031201", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031201", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AC45", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC45" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AC45", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC45" } ], "pmid": "" }, { "name": "vesicle-mediated transport", "id": "GO:0016192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016192", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AC45", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC45" } ], "pmid": "" }, { "name": "vesicle fusion", "id": "GO:0006906", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006906", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AC45", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC45" } ], "pmid": "" }, { "name": "intra-Golgi vesicle-mediated transport", "id": "GO:0006891", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006891", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AC45", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC45" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "SNAP receptor activity", "id": "GO:0005484", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005484", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AC45", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC45" } ], "pmid": "" }, { "name": "SNARE binding", "id": "GO:0000149", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000149", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AC45", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC45" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 233, "end_pos": 235, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AC45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC45" }, { "id": "PF27021", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27021" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BOS1/GOSR2/MEM11 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"total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1ACU9-1", "uniprot_ac": "A0A8V1ACU9", "uniprot_id": "A0A8V1ACU9_CHICK", "mass": { "chemical_mass": 82430.0, "monoisotopic_mass": 82430.0 }, "refseq": {}, "gene_names": [ { "name": "LOC101750889", "type": "recommended", "evidence": [ { "id": "A0A8V1ACU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACU9" } ] } ], "protein_names": [ { "name": "LRRCT domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8V1ACU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACU9/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACU9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACU9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC101750889", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACU9", "locus": {} } ], "crossref": [ { "id": "A0A8V1ACU9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1ACU9", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR000483", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000483", "database": "InterPro", "categories": [ "Protein 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"categories": [ "Protein Classification" ] }, { "id": "PTHR24366", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24366", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24366:SF158", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24366:SF158", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24369", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24369", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24369:SF157", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24369:SF157", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13855", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13855", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1AA36", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA36", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AA36-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA36-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ACU9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACU9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ACU9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACU9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFG9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFG9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFG9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFG9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAVRFPALLPLILAALQPAAVPAEPPPPCPWEMNKVKDIVEVNCTGRDLSAVPAGLPENTGILLLNANRLLSVSTAAFQKLAALQDLDLSDNGLQAVLTEAALPSLKELLLSHNALEALPALQGLPALTRLALAHNKLQALAPTAFRAVLQLQDLDLRGNALRTLPEDVFMGLRALKDLDLSDNALEELPRGLLQDLVTLETLWLSGNRLRALPSGFFPEGHLFAYVFLTENPWHCDCDLVYLRSWILRNEGSVYEPERGLGKTKVEVAPEKVLCQSPSEHLQKPIIRFKPNCGHVGDAEEEEEYEYNDEESTPTHPLVASLSPVYPPSSEEPTTAPHTPTQPPLTTVSPLLTTPAGPSLAPTTFLTTPPSTVAPSTAPPASTSSTTTPPSTVQPSQPPSTATFHTAPRSTPHTPTISLPAAPSTDSHPQSPLTTLTASSPLTVPIRAFSVGPSVLPSPTNPESTSVATSSPSALMSPTLVVPNTTLSIHTPTLSAPLDTTPFPHPSPPLRPPLLCPCSTPAQTPSVLHSQTGVKGLPWKHWVLNHCCLLRWFLYLACLALLLLSVLPLACCLVWMCLMRQHDSLQTQEVQHPLMRWENSTGSHTTHLSIFRSPRQRSTFCTTKEVELCPEVATSHTYCTIKDLGVQRGPPAKSFCTTKELWIHHSPRNASSNPFPVELTATELSSLRSPSAYSPDRGAVSQRAACSTGQSVSSRQELHFQPAIPSHESHAWKCHSFSKGLQFSLAVVSHWEWMVLNSAISL", "length": 762, "header": "tr|A0A8V1ACU9-1|A0A8V1ACU9_CHICK Isoform 1 of LRRCT domain-containing protein OS=Gallus gallus OX=9031 GN=LOC101750889 PE=1 SV=1 CANONICAL=A0A8V1ACU9-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AA36-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACU9/entry#A0A8V1AA36-1", "sequence": { "sequence": "MRRIQLCPAHQPGCRPQAVRFPALLPLILAALQPAAVPAEPPPPCPWEMNKVKDIVEVNCTGRDLSAVPAGLPENTGILLLNANRLLSVSTAAFQKLAALQDLDLSDNGLQAVLTEAALPSLKELLLSHNALEALPALQGLPALTRLALAHNKLQALAPTAFRAVLQLQDLDLRGNALRTLPEDVFMGLRALKDLDLSDNALEELPRGLLQDLVTLETLWLSGNRLRALPSGFFPEGHLFAYVFLTENPWHCDCDLVYLRSWILRNEGSVYEPERGLGKTKVEVAPEKVLCQSPSEHLQKPIIRFKPNCGHVGDAEEEEEYEYNDEESTPTHPLVASLSPVYPPSSEEPTTAPHTPTQPPLTTVSPLLTTPAGPSLAPTTFLTTPPSTVAPSTAPPASTSSTTTPPSTVQPSQPPSTATFHTAPRSTPHTPTISLPAAPSTDSHPQSPLTTLTASSPLTVPIRAFSVGPSVLPSPTNPESTSVATSSPSALMSPTLVVPNTTLSIHTPTLSAPLDTTPFPHPSPPLRPPLLCPCSTPAQTPSVLHSQTGVKGLPWKHWVLNHCCLLRWFLYLACLALLLLSVLPLACCLVWMCLMRQHDSLQTQEVQHPLMRWENSTGSHTTHLSIFRSPRQRSTFCTTKEVELCPEVATSHTYCTIKDLGVQRGPPAKSFCTTKELWIHHSPRNASSNPFPVELTATELSSLRSPSAYSPDRGVSAISAVRVKYAANTL", "length": 730, "header": "tr|A0A8V1AA36-1|A0A8V1ACU9_CHICK Computationally mapped isoform of LRRCT domain-containing protein OS=Gallus gallus OX=9031 GN=LOC101750889 PE=1 SV=1 CANONICAL=A0A8V1ACU9-1" }, "locus": { "chromosome": "28", "start_pos": 1197700, "end_pos": 1194939, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067157.1", "url": "https://www.ensembl.org/id/ENSGALT00010067157.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041061.1", "url": "https://www.ensembl.org/id/ENSGALP00010041061.1" } ] } }, { "isoform_ac": "A0A8V1ACU9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACU9/entry#A0A8V1ACU9-1", "sequence": { "sequence": "MAVRFPALLPLILAALQPAAVPAEPPPPCPWEMNKVKDIVEVNCTGRDLSAVPAGLPENTGILLLNANRLLSVSTAAFQKLAALQDLDLSDNGLQAVLTEAALPSLKELLLSHNALEALPALQGLPALTRLALAHNKLQALAPTAFRAVLQLQDLDLRGNALRTLPEDVFMGLRALKDLDLSDNALEELPRGLLQDLVTLETLWLSGNRLRALPSGFFPEGHLFAYVFLTENPWHCDCDLVYLRSWILRNEGSVYEPERGLGKTKVEVAPEKVLCQSPSEHLQKPIIRFKPNCGHVGDAEEEEEYEYNDEESTPTHPLVASLSPVYPPSSEEPTTAPHTPTQPPLTTVSPLLTTPAGPSLAPTTFLTTPPSTVAPSTAPPASTSSTTTPPSTVQPSQPPSTATFHTAPRSTPHTPTISLPAAPSTDSHPQSPLTTLTASSPLTVPIRAFSVGPSVLPSPTNPESTSVATSSPSALMSPTLVVPNTTLSIHTPTLSAPLDTTPFPHPSPPLRPPLLCPCSTPAQTPSVLHSQTGVKGLPWKHWVLNHCCLLRWFLYLACLALLLLSVLPLACCLVWMCLMRQHDSLQTQEVQHPLMRWENSTGSHTTHLSIFRSPRQRSTFCTTKEVELCPEVATSHTYCTIKDLGVQRGPPAKSFCTTKELWIHHSPRNASSNPFPVELTATELSSLRSPSAYSPDRGAVSQRAACSTGQSVSSRQELHFQPAIPSHESHAWKCHSFSKGLQFSLAVVSHWEWMVLNSAISL", "length": 762, "header": "tr|A0A8V1ACU9-1|A0A8V1ACU9_CHICK Isoform 1 of LRRCT domain-containing protein OS=Gallus gallus OX=9031 GN=LOC101750889 PE=1 SV=1 CANONICAL=A0A8V1ACU9-1" }, "locus": { "chromosome": "28", "start_pos": 1201476, "end_pos": 1195387, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067159.1", "url": "https://www.ensembl.org/id/ENSGALT00010067159.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041063.1", "url": "https://www.ensembl.org/id/ENSGALP00010041063.1" } ] } }, { "isoform_ac": "A0A8V1AFG9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACU9/entry#A0A8V1AFG9-1", "sequence": { "sequence": "MNKVKDIVEVNCTGRDLSAVPAGLPENTGILLLNANRLLSVSTAAFQKLAALQDLDLSDNGLQAVLTEAALPSLKELLLSHNALEALPALQGLPALTRLALAHNKLQALAPTAFRAVLQLQDLDLRGNALRTLPEDVFMGLRALKDLDLSDNALEELPRGLLQDLVTLETLWLSGNRLRALPSGFFPEGHLFAYVFLTENPWHCDCDLVYLRSWILRNEGSVYEPERGLGKTKVEVAPEKVLCQSPSEHLQKPIIRFKPNCGHVGDAEEEEEYEYNDEESTPTHPLVASLSPVYPPSSEEPTTAPHTPTQPPLTTVSPLLTTPAGPSLAPTTFLTTPPSTVAPSTAPPASTSSTTTPPSTVQPSQPPSTATFHTAPRSTPHTPTISLPAAPSTDSHPQSPLTTLTASSPLTVPIRAFSVGPSVLPSPTNPESTSVATSSPSALMSPTLVVPNTTLSIHTPTLSAPLDTTPFPHPSPPLRPPLLCPCSTPAQTPSVLHSQTGVKGLPWKHWVLNHCCLLRWFLYLACLALLLLSVLPLACCLVWMCLMRQHDSLQTQEVQHPLMRWENSTGSHTTHLSIFRSPRQRSTFCTTKEVELCPEVATSHTYCTIKDLGVQRGPPAKSFCTTKELWIHHSPRNASSNPFPVELTATELSSLRSPSAYSPDRGVSAISAVRVKYAANTL", "length": 682, "header": "tr|A0A8V1AFG9-1|A0A8V1AFG9_CHICK Computationally mapped isoform of LRRCT domain-containing protein OS=Gallus gallus OX=9031 GN=LOC101750889 PE=1 SV=1 CANONICAL=A0A8V1ACU9-1" }, "locus": { "chromosome": "28", "start_pos": 1197700, "end_pos": 1195655, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067158.1", "url": "https://www.ensembl.org/id/ENSGALT00010067158.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041062.1", "url": "https://www.ensembl.org/id/ENSGALP00010041062.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 520, "start_aa": "Thr", "end_pos": 520, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr520", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular 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"MPGARRSLASPVVSGVLCPCGSPRAAAAPGPGAEGSGGGPCGRAVCEASEQDRRLRALFQKLDVNRDGALCIHDLAVGLGRLGLHRTELDLLKIVKAGDKDLDGQLDFEEFVHYLQDHEKKLRLVFKSLDKKNDGRIDAQEIVQSLRDLGVKISEQQAEKILKRIRTGHFWGPVTYMDKNGTMTIDWNEWRDYHLLHPVENIPEIILYWKHSTIFDVGENLTVPDEFTVEERQTGMWWRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMCIIGGFTQMIREGGTRSLWRGNGINVLKIAPESAIKFMAYEQIKRFIGTDQEMLRIHERLLAGSLAGAIAQSSIYPMEVLKTRMALRKTGQYSGMLDCAKNILSKEGMAAFYKGYIPNMLGIIPYAGIDLAVYETLKNAWLQRYAVNSADPGVFVLLACGTISSTCGQLASYPLALVRTRMQAQASVEGAPEVTMRGLFKHILKTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKMTLGVQSR", "length": 520, "header": "tr|A0A8V1AES3-1|A0A8V1AES3_CHICK Isoform 1 of Mitochondrial adenyl nucleotide antiporter SLC25A25 OS=Gallus gallus OX=9031 GN=SLC25A25 PE=1 SV=1 CANONICAL=A0A8V1AES3-1" }, "isoforms": [ { "isoform_ac": "A0A3Q3AJ87-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AES3/entry#A0A3Q3AJ87-1", "sequence": { "sequence": "MLQSLWRFLSSFLPRAACQGPADGKDDEARNATPLPGPGEKGPKVLGKPQDRGTDPTERRPTILLVVGPAEHFPKKIVKAGDKDLDGQLDFEEFVHYLQDHEKKLRLVFKSLDKKNDGRIDAQEIVQSLRDLGVKISEQQAEKILKRIRTGHFWGPVTYMDKNGTMTIDWNEWRDYHLLHPVENIPEIILYWKHSTIFDVGENLTVPDEFTVEERQTGMWWRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMCIIGGFTQMIREGGTRSLWRGNGINVLKIAPESAIKFMAYEQIKRFIGTDQEMLRIHERLLAGSLAGAIAQSSIYPMEVLKTRMALRKTGQYSGMLDCAKNILSKEGMAAFYKGYIPNMLGIIPYAGIDLAVYETLKNAWLQRYAVNSADPGVFVLLACGTISSTCGQLASYPLALVRTRMQAQASVEGAPEVTMRGLFKHILKTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKMTLGVQSR", "length": 503, "header": "tr|A0A3Q3AJ87-1|A0A8V1AES3_CHICK Computationally mapped isoform of Mitochondrial adenyl nucleotide antiporter SLC25A25 OS=Gallus gallus OX=9031 GN=SLC25A25 PE=1 SV=1 CANONICAL=A0A8V1AES3-1" }, "locus": { "chromosome": "17", "start_pos": 5485248, "end_pos": 5472788, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067983.1", "url": "https://www.ensembl.org/id/ENSGALT00010067983.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041726.1", "url": "https://www.ensembl.org/id/ENSGALP00010041726.1" } ] } }, { "isoform_ac": "A0A8V1ABW7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AES3/entry#A0A8V1ABW7-1", "sequence": { "sequence": "MLQSLWRFLSSFLPRAACQGPADGKDDEARNATPLPGPGEKGPKVLGKPQDRGTDPTERRPTILLVVGPAEHFPKKIVKAGDKDLDGQLDFEEFVHYLQDHEKKLRLVFKSLDKKNDGRIDAQEIVQSLRDLGVKISEQQAEKILKSMDKNGTMTIDWNEWRDYHLLHPVENIPEIILYWKHSTIFDVGENLTVPDEFTVEERQTGMWWRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMCIIGGFTQMIREGGTRSLWRGNGINVLKIAPESAIKFMAYEQIKRFIGTDQEMLRIHERLLAGSLAGAIAQSSIYPMEVLKTRMALRKTGQYSGMLDCAKNILSKEGMAAFYKGYIPNMLGIIPYAGIDLAVYETLKNAWLQRYAVNSADPGVFVLLACGTISSTCGQLASYPLALVRTRMQAQASVEGAPEVTMRGLFKHILKTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKMTLGVQSR", "length": 491, "header": "tr|A0A8V1ABW7-1|A0A8V1AES3_CHICK Computationally mapped isoform of Mitochondrial adenyl nucleotide antiporter SLC25A25 OS=Gallus gallus OX=9031 GN=SLC25A25 PE=1 SV=1 CANONICAL=A0A8V1AES3-1" }, "locus": { "chromosome": "17", "start_pos": 5485248, "end_pos": 5472788, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067985.1", "url": "https://www.ensembl.org/id/ENSGALT00010067985.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041728.1", "url": "https://www.ensembl.org/id/ENSGALP00010041728.1" } ] } }, { "isoform_ac": "A0A8V1AES3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AES3/entry#A0A8V1AES3-1", "sequence": { "sequence": "MPGARRSLASPVVSGVLCPCGSPRAAAAPGPGAEGSGGGPCGRAVCEASEQDRRLRALFQKLDVNRDGALCIHDLAVGLGRLGLHRTELDLLKIVKAGDKDLDGQLDFEEFVHYLQDHEKKLRLVFKSLDKKNDGRIDAQEIVQSLRDLGVKISEQQAEKILKRIRTGHFWGPVTYMDKNGTMTIDWNEWRDYHLLHPVENIPEIILYWKHSTIFDVGENLTVPDEFTVEERQTGMWWRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMCIIGGFTQMIREGGTRSLWRGNGINVLKIAPESAIKFMAYEQIKRFIGTDQEMLRIHERLLAGSLAGAIAQSSIYPMEVLKTRMALRKTGQYSGMLDCAKNILSKEGMAAFYKGYIPNMLGIIPYAGIDLAVYETLKNAWLQRYAVNSADPGVFVLLACGTISSTCGQLASYPLALVRTRMQAQASVEGAPEVTMRGLFKHILKTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKMTLGVQSR", "length": 520, "header": "tr|A0A8V1AES3-1|A0A8V1AES3_CHICK Isoform 1 of Mitochondrial adenyl nucleotide antiporter SLC25A25 OS=Gallus gallus OX=9031 GN=SLC25A25 PE=1 SV=1 CANONICAL=A0A8V1AES3-1" }, "locus": { "chromosome": "17", "start_pos": 5495374, "end_pos": 5472788, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067987.1", "url": "https://www.ensembl.org/id/ENSGALT00010067987.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041730.1", "url": "https://www.ensembl.org/id/ENSGALP00010041730.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:417230", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417230", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AES3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AES3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "transmembrane transport", "id": "GO:0055085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055085", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AES3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AES3" } ], "pmid": "" }, { "name": "ADP transport", "id": "GO:0015866", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015866", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AES3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AES3" } ], "pmid": "" }, { "name": "ATP transport", "id": "GO:0015867", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015867", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AES3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AES3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "calcium 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"table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AEM9-1", "uniprot_ac": "A0A8V1AEM9", "uniprot_id": "A0A8V1AEM9_CHICK", "mass": { "chemical_mass": 47070.0, "monoisotopic_mass": 47070.0 }, "refseq": {}, "gene_names": [ { "name": "UBAC1", "type": "recommended", "evidence": [ { "id": "A0A8V1AEM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEM9" } ] } ], "protein_names": [ { "name": "Ubiquitin-associated domain-containing protein 1", "type": "recommended", "evidence": [ { "id": "A0A8V1AEM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEM9/entry#names_and_taxonomy" } ] }, { "name": "Kip1 ubiquitination-promoting complex protein 2", "type": "synonym", "evidence": [ { "id": "A0A8V1AEM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEM9/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEM9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEM9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "UBAC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEM9", "locus": { "chromosome": "17", "start_pos": 8782493, "end_pos": 8761818, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027427", "url": "https://www.ensembl.org/id/ENSGALG00010027427" } ] } } ], "crossref": [ { "id": "A0A8V1AEM9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AEM9", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd14303", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14303", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd14304", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14304", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd17066", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17066", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "427754", "url": "https://www.ncbi.nlm.nih.gov/gene/427754", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000626", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000626", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006636", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006636", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009060", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009060", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015940", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015940", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029071", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029071", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041926", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041926", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041927", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041927", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052476", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052476", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057650", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057650", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "WLIQNDS", "url": "https://omabrowser.org/oma/group/WLIQNDS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ABY4", "url": "https://www.orthodb.org/?gene=A0A8V1ABY4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AEM9", "url": "https://www.orthodb.org/?gene=A0A8V1AEM9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46738", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46738", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46738:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46738:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF22562", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22562", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23326", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23326", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-983168", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983168", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1ABY4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABY4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ABY4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABY4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AEM9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEM9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AEM9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEM9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFVQEEKIFAGKVLRLQVCTMEGAEWLEEVPEDTTVEKLKERCLKHCVPGSLEDPKTVTHHKLIHATSEKVLTDSKTVLEENIQDRDVLLLIKKRAPPPLPKMADVSAEEKVLVYVSVSLPVGIGRKQEQKAPDKDAILKATANLPSRNVDRTVAQHNMRDFQTELRKILVSLIEVAQKLLALNPDAVELFKKANAMLDEDEEDRVDEIALRQLTEMGFPESRAVKALRLNHMSVTQAMEWLIEHADDPAVDAPLPGQTPSEAAAEAGASSAEATAGPSSEAGGEEAKDELTEIFKKIRRKREFRPDPRAVIALMEMGFDEKEVVDALRVNNNQQNAACEWLLGDRKPSPEDLDKGIDTNSPLFQAILENPVVQLGLTNPKTLLAFEDMLENPLNSTQWMNDPETGPVMLQISRIFQTLNRT", "length": 422, "header": "tr|A0A8V1AEM9-1|A0A8V1AEM9_CHICK Isoform 1 of Ubiquitin-associated domain-containing protein 1 OS=Gallus gallus OX=9031 GN=UBAC1 PE=4 SV=1 CANONICAL=A0A8V1AEM9-1" }, "isoforms": [ { "isoform_ac": "A0A8V1ABY4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEM9/entry#A0A8V1ABY4-1", "sequence": { "sequence": "MFVQEEKIFAGKVLRLQVCTMEGAEWLEEVPEDTTVEKLKERCLKHCVPGSLEDPKTVTHHKLIHATSEKVLTDSKTVLEENIQDRDVLLLIKKRAPPPLPKMADVSAEEKRKQEQKAPDKDAILKATANLPSRNVDRTVAQHNMRDFPFLQFQTELRKILVSLIEVAQKLLALNPDAVELFKKANAMLDEDEEDRVDEIALRQLTEMGFPESRAVKALRLNHMSVTQAMEWLIEHADDPAVDAPLPGQTPSEAAAEAGASSAEATAGPSSEAGGEEAKDELTEIFKKIRRKREFRPDPRAVIALMEMGFDEKEVVDALRVNNNQQNAACEWLLGDRKPSPEDLDKGIDTNSPLFQAILENPVVQLGLTNPKTLLAFEDMLENPLNSTQWMNDPETGPVMLQISRIFQTLNRT", "length": 413, "header": "tr|A0A8V1ABY4-1|A0A8V1AEM9_CHICK Computationally mapped isoform of Ubiquitin-associated domain-containing protein 1 OS=Gallus gallus OX=9031 GN=UBAC1 PE=4 SV=1 CANONICAL=A0A8V1AEM9-1" }, "locus": { "chromosome": "17", "start_pos": 8777530, "end_pos": 8761986, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066495.1", "url": "https://www.ensembl.org/id/ENSGALT00010066495.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040738.1", "url": "https://www.ensembl.org/id/ENSGALP00010040738.1" } ] } }, { "isoform_ac": "A0A8V1AEM9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEM9/entry#A0A8V1AEM9-1", "sequence": { "sequence": "MFVQEEKIFAGKVLRLQVCTMEGAEWLEEVPEDTTVEKLKERCLKHCVPGSLEDPKTVTHHKLIHATSEKVLTDSKTVLEENIQDRDVLLLIKKRAPPPLPKMADVSAEEKVLVYVSVSLPVGIGRKQEQKAPDKDAILKATANLPSRNVDRTVAQHNMRDFQTELRKILVSLIEVAQKLLALNPDAVELFKKANAMLDEDEEDRVDEIALRQLTEMGFPESRAVKALRLNHMSVTQAMEWLIEHADDPAVDAPLPGQTPSEAAAEAGASSAEATAGPSSEAGGEEAKDELTEIFKKIRRKREFRPDPRAVIALMEMGFDEKEVVDALRVNNNQQNAACEWLLGDRKPSPEDLDKGIDTNSPLFQAILENPVVQLGLTNPKTLLAFEDMLENPLNSTQWMNDPETGPVMLQISRIFQTLNRT", "length": 422, "header": "tr|A0A8V1AEM9-1|A0A8V1AEM9_CHICK Isoform 1 of Ubiquitin-associated domain-containing protein 1 OS=Gallus gallus OX=9031 GN=UBAC1 PE=4 SV=1 CANONICAL=A0A8V1AEM9-1" }, "locus": { "chromosome": "17", "start_pos": 8777530, "end_pos": 8761986, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066493.1", "url": "https://www.ensembl.org/id/ENSGALT00010066493.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040737.1", "url": "https://www.ensembl.org/id/ENSGALP00010040737.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-983168", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983168", "resource": "Reactome", "description": "Antigen processing: Ubiquitination & Proteasome degradation" } ], "orthologs": [ { "uniprot_canonical_ac": "Q5XIR9-1", "protein_name": "Ubiquitin-associated domain-containing protein 1", "gene_name": "Ubac1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFVQEEKIFAGKVLRLHICAADGSEWLEEATEDTSVEKLKESCLKHGAHGSLEDPKNVTHHKLIHAASERVLSDSKTILEENIQDQDVLLLIKKRAPSPIPKMADVSAEEKKKQEQKAPDKDAILRATANLPACSTDRTAVQTTMRDFQTELRKILVSLIEVAQKLLALNPDAVELFKKANAMLDEDEDERVDETALRQLTEMGFPESRASKALRLNHMSVPQAMEWLIEHSEDPAIDTPLPGHAAQAEASAAAATSSSSSEAAVGTSVEDEESRDELTEIFKKIRRKKEFRADARAVISLMEMGFDEKEVIDALRVNNNQQNAACEWLLGDRKPSPEELDQGIDPNSPLFQAILDNPVVQLGLTNPKTLLAFEDMLENPLNSTQWMNDPETGPVMLQISRIFQTLNRT", "length": 409 }, "evidence": [ { "id": "A0A8V1AEM9", "url": "https://omabrowser.org/oma/group/A0A8V1AEM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8VDI7-1", "protein_name": "Ubiquitin-associated domain-containing protein 1", "gene_name": "Ubac1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFVQEEKIFAGKVLRLHICAADGAEWLEEATEDTSVEKLKESCLKHGAHGSLEDPKNVTHHKLIHAASERVLSDSKTILEENIQDQDVLLLIKKRVPSPLPKMADVSAEEKKKQEQKAPDKDAILRATANLPACSTDRTAVQTTMRDFQTELRKILVSLIEVAQKLLALNPDAVELFKKANAMLDEDEDERVDETALRQLTEMGFPESRASKALRLNHMSVPQAMEWLIEHSEDPAIDTPLPGHAAQAGASAAATTSSTSSEAAVGTSVEDEESRDELTEIFKKIRRKKEFRADARAVISLMEMGFDEKEVIDALRVNNNQQNAACEWLLGDRKPSPEELDQGIDPNSPLFQAILDNPVVQLGLTNPKTLLAFEDMLENPLNSTQWMNDPETGPVMLQISRIFQTLNRT", "length": 409 }, "evidence": [ { "id": "A0A8V1AEM9", "url": "https://omabrowser.org/oma/group/A0A8V1AEM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9BSL1-1", "protein_name": "Ubiquitin-associated domain-containing protein 1", "gene_name": "UBAC1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MFVQEEKIFAGKVLRLHICASDGAEWLEEATEDTSVEKLKERCLKHCAHGSLEDPKSITHHKLIHAASERVLSDARTILEENIQDQDVLLLIKKRAPSPLPKMADVSAEEKKKQDQKAPDKEAILRATANLPSYNMDRAAVQTNMRDFQTELRKILVSLIEVAQKLLALNPDAVELFKKANAMLDEDEDERVDEAALRQLTEMGFPENRATKALQLNHMSVPQAMEWLIEHAEDPTIDTPLPGQAPPEAEGATAAASEAAAGASATDEEARDELTEIFKKIRRKREFRADARAVISLMEMGFDEKEVIDALRVNNNQQNAACEWLLGDRKPSPEELDKGIDPDSPLFQAILDNPVVQLGLTNPKTLLAFEDMLENPLNSTQWMNDPETGPVMLQISRIFQTLNRT", "length": 405 }, "evidence": [ { "id": "A0A8V1AEM9", "url": "https://omabrowser.org/oma/group/A0A8V1AEM9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEM9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEM9" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEM9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEM9" } ], "pmid": "" }, { "name": "ubiquitin ligase complex", "id": "GO:0000151", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000151", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEM9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEM9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "polyubiquitin modification-dependent protein binding", "id": "GO:0031593", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031593", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEM9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEM9" } ], "pmid": "" }, { "name": "proteasome binding", "id": "GO:0070628", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070628", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEM9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEM9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEM9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEM9" } ], "pmid": "" }, { "name": "protein maturation", "id": "GO:0051604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051604", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEM9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEM9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 395, "end_pos": 397, "annotation": "n_glycosylation_sequon" }, { "start_pos": 420, "end_pos": 422, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AEM9", 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1ACF4-1", "uniprot_ac": "A0A8V1ACF4", "uniprot_id": "A0A8V1ACF4_CHICK", "mass": { "chemical_mass": 23548.0, "monoisotopic_mass": 23548.0 }, "refseq": { "ac": "XP_015148282", "name": "transmembrane reductase CYB561D2 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015148282" }, "gene_names": [ { "name": "CYB561D2", "type": "recommended", "evidence": [ { "id": "A0A8V1ACF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF4" } ] }, { "name": "CYB561D2", "type": "synonym", "evidence": [ { "id": "XP_015148282", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015148282" } ] } ], "protein_names": [ { "name": "ascorbate ferrireductase (transmembrane)", "type": "recommended", "evidence": [ { "id": "A0A8V1ACF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF4/entry#names_and_taxonomy" } ] }, { "name": "7.2.1.3", "type": "synonym", "evidence": [ { "id": "A0A8V1ACF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF4/entry#names_and_taxonomy" } ] }, { "name": "transmembrane reductase CYB561D2 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_015148282", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015148282" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052543.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015148282", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015148282" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACF4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CYB561D2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF4", "locus": { "chromosome": "12", "start_pos": 1542200, "end_pos": 1539632, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028129", "url": "https://www.ensembl.org/id/ENSGALG00010028129" } ] } } ], "crossref": [ { "id": "A0A8V1ACF4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1ACF4", "database": 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"http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15422", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15422:SF21", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15422:SF21", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03188", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03188", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015148282", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015148282", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1ACF4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ACF4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHL4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHL4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHL4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHL4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MALTAESESRLFRSLRAAAGAAAHAAALGLPAGVAVLARPGSSLFSWHPLLMALAVSLLMTEALLAFSPEASPLRGLSRKAKARAHWVLQALAVLCAALGLGLVAYNKHLHGTGHLRTWHGRIGLLTVLYFAVQSLGGLPLLYPKLAGSWPPGKLRLYHATAGLVGYLLGCASLTLGMCSLWFTTAARGAAWYLAVLCPVLTSLVVMNQVSNAYLYRKRSQH", "length": 222, "header": "tr|A0A8V1ACF4-1|A0A8V1ACF4_CHICK Isoform 1 of ascorbate ferrireductase (transmembrane) OS=Gallus gallus OX=9031 GN=CYB561D2 PE=4 SV=1 CANONICAL=A0A8V1ACF4-1" }, "isoforms": [ { "isoform_ac": "A0A8V1ACF4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF4/entry#A0A8V1ACF4-1", "sequence": { "sequence": "MALTAESESRLFRSLRAAAGAAAHAAALGLPAGVAVLARPGSSLFSWHPLLMALAVSLLMTEALLAFSPEASPLRGLSRKAKARAHWVLQALAVLCAALGLGLVAYNKHLHGTGHLRTWHGRIGLLTVLYFAVQSLGGLPLLYPKLAGSWPPGKLRLYHATAGLVGYLLGCASLTLGMCSLWFTTAARGAAWYLAVLCPVLTSLVVMNQVSNAYLYRKRSQH", "length": 222, "header": "tr|A0A8V1ACF4-1|A0A8V1ACF4_CHICK Isoform 1 of ascorbate ferrireductase (transmembrane) OS=Gallus gallus OX=9031 GN=CYB561D2 PE=4 SV=1 CANONICAL=A0A8V1ACF4-1" }, "locus": { "chromosome": "12", "start_pos": 1541634, "end_pos": 1540822, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068158.1", "url": "https://www.ensembl.org/id/ENSGALT00010068158.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041901.1", "url": "https://www.ensembl.org/id/ENSGALP00010041901.1" } ] } }, { "isoform_ac": "A0A8V1AHL4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF4/entry#A0A8V1AHL4-1", "sequence": { "sequence": "MPLEHGQAVGHQPPPWEAWCSKAAFPTAQPEPPRSAQPPHLQRGEVPRQLLDDGLQRAGLGSRVADEAEVEEQGVAAVLLVLDAHRAADQLLLHGGAAGGQEPVPSAGAAGLFSWHPLLMALAVSLLMTEALLAFSPEASPLRGLSRKAKARAHWVLQALAVLCAALGLGLVAYNKHLHGTGHLRTWHGRIGLLTVLYFAVQSLGGLPLLYPKLAGSWPPGKLRLYHATAGLVGYLLGCASLTLGMCSLWFTTAARGAAWYLAVLCPVLTSLVVMNQVSNAYLYRKRSQH", "length": 290, "header": "tr|A0A8V1AHL4-1|A0A8V1ACF4_CHICK Computationally mapped isoform of ascorbate ferrireductase (transmembrane) OS=Gallus gallus OX=9031 GN=CYB561D2 PE=4 SV=1 CANONICAL=A0A8V1ACF4-1" }, "locus": { "chromosome": "12", "start_pos": 1541634, "end_pos": 1539831, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068159.1", "url": "https://www.ensembl.org/id/ENSGALT00010068159.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041902.1", "url": "https://www.ensembl.org/id/ENSGALP00010041902.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACF4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF4" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACF4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF4" } ], "pmid": "" }, { "name": "vesicle", "id": "GO:0031982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031982", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACF4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACF4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF4" } ], "pmid": "" }, { "name": "transmembrane monodehydroascorbate reductase activity", "id": "GO:0140575", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140575", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACF4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF4" } ], "pmid": "" }, { "name": "transmembrane ascorbate ferrireductase activity", "id": "GO:0140571", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140571", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACF4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF4" } ], "pmid": "" }, { "name": "heme binding", "id": "GO:0020037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0020037", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACF4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "ascorbate homeostasis", "id": "GO:0140576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140576", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACF4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1ACF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF4" }, { "id": "PS50939", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50939" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Cytochrome b561", "eco_id": "ECO_0000259", "start_pos": 11, "end_pos": 217, "start_aa": "Leu", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "7.2.1.3", "ec_name": "Fe(3+)(out) + L-ascorbate(in) = monodehydro-L-ascorbate radical(in) + Fe(2+)(out) + H(+).", "evidence": [ { "id": "7.2.1.3", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:7.2.1.3" }, { "id": "7.2.1.3", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=7.2.1.3" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AAU2-1", "uniprot_ac": "A0A8V1AAU2", "uniprot_id": "A0A8V1AAU2_CHICK", "mass": { "chemical_mass": 34425.0, "monoisotopic_mass": 34425.0 }, "refseq": {}, "gene_names": [ { "name": "AQP10", "type": "recommended", "evidence": [ { "id": "A0A8V1AAU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAU2" } ] } ], "protein_names": [ { "name": "Aquaporin 10", "type": "synonym", "evidence": [ { "id": "A0A8V1AAU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAU2/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Aquaglyceroporins form homotetrameric transmembrane channels, with each monomer independently mediating glycerol and water transport across the plasma membrane along their osmotic gradient. Could also be permeable to urea. Also participates in cell permeability to H2O2 and H2O2-mediated signaling. In skin, transports glycerol to the epidermis and stratum corneum, where it maintains hydration, elasticity, and supports lipid biosynthesis for barrier repair. In kidney, contributes to the reabsorption of water, helping the body maintain proper fluid balance.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A5Y1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5Y1#function" }, { "database": "UniProtKB", "id": "ARBA00049592", "url": "https://www.uniprot.org/uniprotkb/ARBA00049592#function" }, { "database": "UniProtKB", "id": "A0A8V1AG63", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG63#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAU2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAU2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "AQP10", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAU2", "locus": { "chromosome": "25", "start_pos": 1925822, "end_pos": 1922745, 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"database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AAU2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAU2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AG63", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG63", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AG63-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG63-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGRGCCVGAERGAGRSRVPVLQLITLGGAAQMVTSSGTKGNVITSSLAGALAVMVAIYTAGGVSGAHLNPAFSLAMSLLGQLPWWKFPIFVAVQIFGSFIAAAAVYALYYGTQSPRWGRGWARSRGGSAAARLCPADAIWSYSNGTLTASGPRETASIFATYPAEHLSLPNGFLDQVLGTAVLITGILAITDTRNHAVPRGLEPVAVALLVLAIEVSMGSNCGCPMNPARDLGPRLFTLLAGWGTEVFRWVRAVGPGGKVGGHRLDAPHPRLRWQQGQRVVVGAGGGPAGGGRAGHGALSALRGLPPPRGGGGGGRRPSTQADQALTAPRRPRRG", "length": 335, "header": "tr|A0A8V1AAU2-1|A0A8V1AAU2_CHICK Isoform 1 of Aquaporin 10 OS=Gallus gallus OX=9031 GN=AQP10 PE=3 SV=1 CANONICAL=A0A8V1AAU2-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A5Y1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAU2/entry#A0A8V1A5Y1-1", "sequence": { "sequence": "MGRGCCVGAERGAGRSRVPVLQLITLGGAAQMVTSSGTKGNVITSSLAGALAVMVAIYTAGGVSGAHLNPAFSLAMSLLGQLPWWKFPIFVAVQIFGSFIAAAAVYALYYDAIWSYSNGTLTASGPRETASIFATYPAEHLSLPNGFLDQVLGTAVLITGILAITDTRNHAVPRGLEPVAVALLVLAIEVSMGSNCGCPMNPARDLGPRLFTLLAGWGTEVFSRGSAWWWVPVVAPLVGAALGTGLYQLFVAFHHPEEEEEEDGGRARRQTKH", "length": 273, "header": "tr|A0A8V1A5Y1-1|A0A8V1AAU2_CHICK Computationally mapped isoform of Aquaporin 10 OS=Gallus gallus OX=9031 GN=AQP10 PE=3 SV=1 CANONICAL=A0A8V1AAU2-1" }, "locus": { "chromosome": "25", "start_pos": 1925757, "end_pos": 1924151, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067569.1", "url": "https://www.ensembl.org/id/ENSGALT00010067569.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041312.1", "url": "https://www.ensembl.org/id/ENSGALP00010041312.1" } ] } }, { "isoform_ac": "A0A8V1AAU2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAU2/entry#A0A8V1AAU2-1", "sequence": { "sequence": "MGRGCCVGAERGAGRSRVPVLQLITLGGAAQMVTSSGTKGNVITSSLAGALAVMVAIYTAGGVSGAHLNPAFSLAMSLLGQLPWWKFPIFVAVQIFGSFIAAAAVYALYYGTQSPRWGRGWARSRGGSAAARLCPADAIWSYSNGTLTASGPRETASIFATYPAEHLSLPNGFLDQVLGTAVLITGILAITDTRNHAVPRGLEPVAVALLVLAIEVSMGSNCGCPMNPARDLGPRLFTLLAGWGTEVFRWVRAVGPGGKVGGHRLDAPHPRLRWQQGQRVVVGAGGGPAGGGRAGHGALSALRGLPPPRGGGGGGRRPSTQADQALTAPRRPRRG", "length": 335, "header": "tr|A0A8V1AAU2-1|A0A8V1AAU2_CHICK Isoform 1 of Aquaporin 10 OS=Gallus gallus OX=9031 GN=AQP10 PE=3 SV=1 CANONICAL=A0A8V1AAU2-1" }, "locus": { "chromosome": "25", "start_pos": 1925786, "end_pos": 1924151, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067571.1", "url": "https://www.ensembl.org/id/ENSGALT00010067571.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041314.1", "url": "https://www.ensembl.org/id/ENSGALP00010041314.1" } ] } }, { "isoform_ac": "A0A8V1AG63-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAU2/entry#A0A8V1AG63-1", "sequence": { "sequence": "MGRGCCVGAERGAGRSRVPVLQLITLGGAAQMVTSSGTKGNVITSSLAGALAVMVAIYTAGGVSGAHLNPAFSLAMSLLGQLPWWKFPIFVAVQIFGSFIAAAAVYALYYDAIWSYSNGTLTASGPRETASIFATYPAEHLSLPNGFLDQVLGTAVLITGILAITDTRNHAVPRGLEPVAVALLVLAIEVSMGSNCGCPMNPARDLGPRLFTLLAGWGTEVFRWVRAVGPGGKVGGHRLDAPHPRLRWQQGQRVVVGAGGGPAGGGRAGHGALSALRGLPPPRGGGGGGRRPSTQADQALTAPRRPRRG", "length": 309, "header": "tr|A0A8V1AG63-1|A0A8V1AAU2_CHICK Computationally mapped isoform of Aquaporin 10 OS=Gallus gallus OX=9031 GN=AQP10 PE=3 SV=1 CANONICAL=A0A8V1AAU2-1" }, "locus": { "chromosome": "25", "start_pos": 1925786, "end_pos": 1924151, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067572.1", "url": "https://www.ensembl.org/id/ENSGALT00010067572.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041315.1", "url": "https://www.ensembl.org/id/ENSGALP00010041315.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": 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"header": "tr|A0A8V1AB38-1|A0A8V1AB38_CHICK Isoform 1 of Centromere protein X OS=Gallus gallus OX=9031 GN=CENPX PE=3 SV=1 CANONICAL=A0A8V1AB38-1" }, "locus": { "chromosome": "18", "start_pos": 5629524, "end_pos": 5628400, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070499.1", "url": "https://www.ensembl.org/id/ENSGALT00010070499.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043190.1", "url": "https://www.ensembl.org/id/ENSGALP00010043190.1" } ] } }, { "isoform_ac": "A0A8V1AGF1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB38/entry#A0A8V1AGF1-1", "sequence": { "sequence": "MSCEETVERLLRLHFRDGRTRVNGDALLLMAELLKVFVREAAARAARQAQAEDLEKVDIEHVEKVLPQLLLDF", "length": 73, "header": "tr|A0A8V1AGF1-1|A0A8V1AB38_CHICK Computationally mapped isoform of Centromere protein X OS=Gallus gallus OX=9031 GN=CENPX PE=3 SV=1 CANONICAL=A0A8V1AB38-1" }, "locus": { "chromosome": "18", "start_pos": 5629524, "end_pos": 5628245, "strand": "-", "evidence": [ 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Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AB38", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB38" } ], "pmid": "" }, { "name": "kinetochore", "id": "GO:0000776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000776", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AB38", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB38" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], 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"count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { 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"database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008271", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008271", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017441", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017441", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ABR8", "url": "https://www.orthodb.org/?gene=A0A8V1ABR8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AH35", "url": "https://www.orthodb.org/?gene=A0A8V1AH35", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AIW9", "url": "https://www.orthodb.org/?gene=A0A8V1AIW9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24347", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24347", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00069", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00069", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "17989", "url": "https://www.rhea-db.org/rhea/17989", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "46608", "url": "https://www.rhea-db.org/rhea/46608", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1ABR8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ABR8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AH35", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH35", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AH35-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH35-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AIW9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIW9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AIW9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIW9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLGSVLPGSCWETPLPPPSAGTMPSSKTDGEYWIDGSHREAALEDFYVVGPELGRRAVVFRRAPREMRRCSKGSPLGSNGQQWAAMGSDGSLCSWGRFWCKKRGATSVVYSCEEKGTRTPYAAKILKKTIDKKIVRTEIGVLLRLSHPNIIKLKEIFETPSEIALVLELVTGGELFDRIVERGFYSERDAAHVVKQILEAVSYLHENGVVHRDLKPENLLYADLSPDAPLKIGDFGLSKIVDEQDTMKTVCGTPGYCAPEILHGCPYGPEVDMWSVGVITYILLCGFEPFFDPRGDQYMYSRILTCDYEFVSPWWDEVSLNAKDLVRKLIVLDPQKRLTVYQALEHPWVTGKAAKFAHMDSTQKKLQEFNARRKLKAAMKAVVASSRLGNHGHHDCSRSRGGPRGRESTEATSASEELEAFPAVPTVPVNGASCRS", "length": 436, "header": "tr|A0A8V1ABR8-1|A0A8V1ABR8_CHICK Isoform 1 of Calcium/calmodulin-dependent protein kinase type IV OS=Gallus gallus OX=9031 GN=CAMK4L PE=3 SV=1 CANONICAL=A0A8V1ABR8-1" }, "isoforms": [ { "isoform_ac": "A0A8V1ABR8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR8/entry#A0A8V1ABR8-1", "sequence": { "sequence": "MLGSVLPGSCWETPLPPPSAGTMPSSKTDGEYWIDGSHREAALEDFYVVGPELGRRAVVFRRAPREMRRCSKGSPLGSNGQQWAAMGSDGSLCSWGRFWCKKRGATSVVYSCEEKGTRTPYAAKILKKTIDKKIVRTEIGVLLRLSHPNIIKLKEIFETPSEIALVLELVTGGELFDRIVERGFYSERDAAHVVKQILEAVSYLHENGVVHRDLKPENLLYADLSPDAPLKIGDFGLSKIVDEQDTMKTVCGTPGYCAPEILHGCPYGPEVDMWSVGVITYILLCGFEPFFDPRGDQYMYSRILTCDYEFVSPWWDEVSLNAKDLVRKLIVLDPQKRLTVYQALEHPWVTGKAAKFAHMDSTQKKLQEFNARRKLKAAMKAVVASSRLGNHGHHDCSRSRGGPRGRESTEATSASEELEAFPAVPTVPVNGASCRS", "length": 436, "header": "tr|A0A8V1ABR8-1|A0A8V1ABR8_CHICK Isoform 1 of Calcium/calmodulin-dependent protein kinase type IV OS=Gallus gallus OX=9031 GN=CAMK4L PE=3 SV=1 CANONICAL=A0A8V1ABR8-1" }, "locus": { "chromosome": "28", "start_pos": 3601661, "end_pos": 3594665, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067933.1", "url": "https://www.ensembl.org/id/ENSGALT00010067933.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041676.1", "url": "https://www.ensembl.org/id/ENSGALP00010041676.1" } ] } }, { "isoform_ac": "A0A8V1AH35-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR8/entry#A0A8V1AH35-1", "sequence": { "sequence": "MPSSKTDGEYWIDGSHREAALEDFYVVGPELGRGATSVVYSCEEKGTRTPYAAKILKKTIDKKIVRTEIGVLLRLSHPNIPAAARCRRPCGVSQLVTRPAKIKLKEIFETPSEIALVLELVTGGELFDRIVERGFYSERDAAHVVKQILEAVSYLHENGVVHRDLKPENLLYADLSPDAPLKIGDFGLSKIVDEQDTMKTVCGTPGYCAPEILHGCPYGPEVDMWSVGVITYILLCGFEPFFDPRGDQYMYSRILTCDYEFVSPWWDEVSLNAKDLVRKLIVLDPQKRLTVYQALEHPWVTGKAAKFAHMDSTQKKLQEFNARRKLKAAMKAVVASSRLGNHGHHDCSRSRGGPRGRESTEATSASEELEAFPAVPTVPVNGASCRS", "length": 387, "header": "tr|A0A8V1AH35-1|A0A8V1ABR8_CHICK Computationally mapped isoform of Calcium/calmodulin-dependent protein kinase type IV OS=Gallus gallus OX=9031 GN=CAMK4L PE=3 SV=1 CANONICAL=A0A8V1ABR8-1" }, "locus": { "chromosome": "28", "start_pos": 3601661, "end_pos": 3594731, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067934.1", "url": "https://www.ensembl.org/id/ENSGALT00010067934.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041677.1", "url": "https://www.ensembl.org/id/ENSGALP00010041677.1" } ] } }, { "isoform_ac": "A0A8V1AIW9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR8/entry#A0A8V1AIW9-1", "sequence": { "sequence": "MAPAQASPNGAAPSQWHSPIPIPMAQPHPHPNGTAPSPSQWHSPIPIPMAQPHPHPNGTAPLQWHIPIPFPMAQPQPNGTAPTQRHSPIAMAQPHPYLNGTALSQWHSPIPIPMAHPYPSGTAPSAATHSHPFQIKLKEIFETPSEIALVLELVTGGELFDRIVERGFYSERDAAHVVKQILEAVSYLHENGVVHRDLKPENLLYADLSPDAPLKIGDFGLSKIVDEQDTMKTVCGTPGYCAPEILHGCPYGPEVDMWSVGVITYILLCGFEPFFDPRGDQYMYSRILTCDYEFVSPWWDEVSLNAKDLVRKLIVLDPQKRLTVYQALEHPWVTGKAAKFAHMDSTQKKLQEFNARRKLKAAMKAVVASSRLGNHGHHDCSRSRGGPRGRESTEATSASEELEAFPAVPTVPVNGASCRS", "length": 420, "header": "tr|A0A8V1AIW9-1|A0A8V1ABR8_CHICK Computationally mapped isoform of Calcium/calmodulin-dependent protein kinase type IV OS=Gallus gallus OX=9031 GN=CAMK4L PE=3 SV=1 CANONICAL=A0A8V1ABR8-1" }, "locus": { "chromosome": "28", "start_pos": 3601661, "end_pos": 3599093, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067932.1", "url": "https://www.ensembl.org/id/ENSGALT00010067932.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041675.1", "url": "https://www.ensembl.org/id/ENSGALP00010041675.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABR8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR8" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABR8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR8" } ], "pmid": "" }, { "name": "calmodulin binding", "id": "GO:0005516", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005516", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABR8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR8" } ], "pmid": "" }, { "name": "calcium/calmodulin-dependent protein kinase activity", "id": "GO:0004683", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004683", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABR8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR8" } ], "pmid": "" }, { "name": "protein kinase activity", "id": "GO:0004672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004672", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABR8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABR8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR8" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABR8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "inflammatory response", "id": "GO:0006954", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006954", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABR8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR8" } ], "pmid": "" }, { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABR8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR8" } ], "pmid": "" }, { "name": "adaptive immune response", "id": "GO:0002250", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002250", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABR8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "17989", "name": "", "equation": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q6U1I9-1", "A0A8V0XNJ2-1", "A0A8V0ZUL0-1", "A0A8V0ZT63-1", "A0A8V1ACW2-1", "A0A8V0Z1X0-1", "A0A8V0YHN2-1", "A0A8V0YMN5-1", "A0A8V0Z807-1", "A0A8V0Z930-1", "A0A8V0YFR6-1", "A0A1D5P0M9-1", "A0A8V0ZBN6-1", "A0A3Q2U9U9-1", "A0A8V0YXZ5-1", "A0A8V0ZSP4-1", "A0A8V0ZXQ9-1", "A0A8V0ZZV3-1", "A0A8V1ADF0-1", "A0A8V0ZFT3-1", "A0A8V0ZA45-1", "A0A8V0ZB33-1", "A0A8V0ZD70-1", "A0A8V0Z8T4-1", "R4GIN8-1", "A0A8V0ZK64-1", "A0A8V0ZC16-1", "A0A8V0ZWW1-1", "E1BY69-1", "A0A8V0ZDW9-1", "A0A8V0ZKA2-1", "A0A3Q3B2F1-1", "F1P356-1", "A0A8V1AHA8-1", "Q8QFP8-1", "F1P011-1", "A0A8V0YKK3-1", "A0A1D5NWT4-1", "A0A1D5PMQ7-1", "E1BWA3-1", "F1NVF2-1", "A0A1D5PXN4-1", "A0A3Q2TY19-1", "A0A3Q2U592-1", "A0A8V0XCV5-1", "A0A1D5P8A9-1", "A0A1D5PMG2-1", "A0A8V0X1Q7-1", "A0A8V0Y935-1", "A0A8V0YM96-1", "A0A8V0YF83-1", "A0A8V0YJP9-1", "A0A8V1AKW4-1", "A0A8V0ZSB4-1", "F1NBT0-1", "P18652-1", "P21868-1", "P21869-1", "P53666-1", "P79996-1", "Q5F3W3-1", "Q5ZJS0-1", "Q5ZKN1-1", "Q5ZLL1-1", "A0A8V0XCS0-1", "A0A8V0XNK8-1", "A0A8V0XLV6-1", "A0A8V0XDR5-1", "E1BYH2-1", "E1BQN6-1", "A0A8V0XU71-1", "Q5ZJH6-1", "A0A8V0Y3D1-1", "A0A8V0Y7C3-1", "A0A8V0YCY4-1", "A0A8V0YIV6-1", "A0A8V0YK18-1", "A0A8V0YM22-1", "A0A8V0YTN5-1", "A0A8V0YTP2-1", "Q5F3L1-1", "A0A8V0Y3L2-1", "A0A8V0YCY8-1", "A0A8V0Y9Q1-1", "A0A8V0ZD48-1", "A0A8V0ZD60-1", "A0A8V0ZBZ2-1", "A0A8V0Z9J0-1", "A0A8V1ABF3-1", "Q8AYC9-1", "A0A8V0Z927-1", "A0A8V1A2T9-1", "Q5ZKI0-1", "Q7T0B1-1", "P10741-1", "A0A8V0YFH4-1", "E1C848-1", "A0A8V0X8M1-1", "E1BW33-1", "A0A8V0Z283-1", "A0A8V0Z157-1", "A0A3Q2U4X3-1", "A0A8V0XW11-1", "E1BUG0-1", "A0A8V1ABP4-1", "A0A8V1AJA4-1", "A0A8V1AEH4-1", "F1NJH1-1", "A0A8V1AMK5-1", "A0A3Q2TRY2-1", "A0A8V0X3D6-1", "A0A1D5PD64-1", "A0A8V0XQ97-1", "R4GJB8-1", "A0A8V0X5Z8-1", "A0A8V0XG21-1", "A0A8V0XB58-1", "A0A8V0XMX8-1", "A0A8V0XQS0-1", "A0A8V0XW29-1", "A0A8V0Y074-1", "A0A8V0XXB8-1", "A0A8V0XQ14-1", "A0A8V0XMT1-1", "A0A8V0Y457-1", "A0A8V0Y823-1", "A0A8V0Y4L8-1", "A0A8V0XND6-1", "A0A8V0YZ74-1", "A0A8V0YTI1-1", "A0A8V0YLV1-1", "A0A8V0Z2E3-1", "A0A8V0YCV9-1", "A0A8V0YSH3-1", "A0A8V0YYX2-1", "A0A8V0YZY4-1", "Q5ZIU3-1", "A0A8V0YZK0-1", "A0A8V0ZKM9-1", "A0A8V0ZWC7-1", "A0A8V1A1Y7-1", "A0A8V1A069-1", "A0A8V0ZI32-1", "A0A8V0ZH91-1", "E1BQV7-1", "A0A8V0ZRX1-1", 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"A0A8V0XQQ4-1", "A0A8V0XKG0-1" ], "evidence": [ { "id": "17989", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/17989" } ] }, { "id": "46608", "name": "", "equation": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A1D5PUY5-1", "Q6U1I9-1", "A0A8V0XNJ2-1", "A0A8V0ZUL0-1", "A0A8V0ZT63-1", "A0A8V1ACW2-1", "A0A8V0Z1X0-1", "A0A8V0YHN2-1", "A0A8V0YMN5-1", "A0A8V0Z807-1", "A0A8V0Z930-1", "A0A8V0YFR6-1", "A0A1D5P0M9-1", "A0A8V0ZBN6-1", "A0A3Q2U9U9-1", "A0A8V0YRC9-1", "A0A8V0YXZ5-1", "A0A8V0ZSP4-1", "A0A8V0ZXQ9-1", "A0A8V0ZZV3-1", "A0A8V1ADF0-1", "A0A8V0ZFT3-1", "A0A8V0ZA45-1", "A0A8V0ZB33-1", "A0A8V0ZD70-1", "A0A8V0Z8T4-1", "R4GIN8-1", "A0A8V0ZK64-1", "A0A8V0ZC16-1", "A0A8V0ZWW1-1", "E1BY69-1", "A0A8V0ZDW9-1", "A0A8V0ZKA2-1", "A0A3Q3B2F1-1", "F1P356-1", "A0A8V1AHA8-1", "Q8QFP8-1", "F1P011-1", "A0A8V0YKK3-1", "A0A1D5NWT4-1", 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"A0A8V0ZZE4-1", "P05625-1", "P13863-1", "Q04982-2", "Q0GGW5-1", "Q6XUX0-1", "Q8QGX4-1", "Q9I9E0-1", "Q9IA88-1", "Q5ZJK4-1", "A0A1D5PTJ8-1", "E1C2I2-1", "F1NCX7-1", "F1NKW3-1", "A0A8V1A0W4-1", "A0A8V1A4J8-1", "A0A8V1ACK0-1", "F1NCY7-1", "A0A8V0X6T4-1", "A0A8V0XUM6-1", "A0A8V0XEA3-1", "A0A8V0YHH2-1", "A0A3Q2UI52-1", "A0A8V0ZZK5-1", "A0A8V0ZPX2-1", "A0A8V1ACB5-1", "A0A8V0YDH4-1", "A0A8V1AFS4-1", "A0A8V1AH12-1", "A0A8V0ZQT5-1", "A0A8V0ZFP1-1", "E1C764-1", "F1P4G3-1", "A0A8V0Y2I5-1", "A0A8V0ZLU3-1", "A0A8V0ZNP7-1", "A0A8V0Z2Z3-1", "A0A8V0YNI5-1", "Q90771-1", "A0A8V0X4P0-1", "A0A8V0X7R2-1", "A0A3Q3A664-1", "A0A8V0YGW2-1", "E1C581-1", "A0A8V1AC40-1", "A0A3Q2TUS7-1", "A0A1D5PA08-1", "A0A8V0XFW1-1", "A0A8V0XAH9-1", "A0A8V0ZFM2-1", "A0A8V1A4A1-1", "A0A8V0ZD40-1", "A0A8V0Z6T1-1", "A0A8V1A4V7-1", "A0A8V0YZF2-1", "E1BX69-1", "A0A8V0Y955-1", "A0A1D5PB73-1", "A0A1D5PV76-1", "A0A1D5PX90-1", "A0A1L1RWI9-1", "A0A3Q2TV19-1", "A0A3Q2UF44-1", "A0A8V0X4Q3-1", "A0A8V0Z124-1", "A0A8V0Z6K4-1", "A0A8V1AIY7-1", "A0A8V1AE45-1", "A0A8V0YZV9-1", "A0A8V0YYZ3-1", "A0A8V0ZUC6-1", "A0A8V0ZUU8-1", "A0A8V1AG70-1", "F1NA68-1", "F1NLR7-1", "A0A8V0Y6K1-1", "A0A8V0XS42-1", "A0A8V0YRN4-1", "A0A8V0YFP8-1", "A0A8V1A7P9-1", "A0A1D5PRN8-1", "A0A3Q3AAD7-1", "A0A3Q2TWZ8-1", "A0A8V0XBZ0-1", "A0A8V0XFX2-1", "A0A8V0YFL1-1", "A0A8V0YTL9-1", "A0A8V0YMB3-1", "A0A8V0X2Y2-1", "A0A8V0XCY6-1", "A0A3Q2UI62-1", "A0A8V0Y241-1", "A0A8V0Z8G2-1", "A0A8V1ABR8-1", "A0A8V1AP60-1", "A0A8V0YZM1-1", "A0A8V0ZB38-1", "A0A8V0Z466-1", "A0A8V0ZA06-1", "A0A8V1AMQ2-1", "A0A8V0ZGY3-1", "A0A8V0ZQJ2-1", "A0A8V0ZYU6-1", "A0A8V1A513-1", "A0A8V0XE48-1", "A0A8V0XKG0-1" ], "evidence": [ { "id": "46608", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/46608" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5NWT4", "gene_name": "RPS6KA3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5NWT4", "database": 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"ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5PA08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PA08" } ] } ] }, { "uniprot_ac": "A0A1D5PB73", "gene_name": "CASK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PB73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PB73" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5PB73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PB73" } ] } ] }, { "uniprot_ac": "A0A1D5PD64", "gene_name": "MAP2K3", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PD64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PD64" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": 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{ "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XCY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCY6" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V0XCY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCY6" } ] } ] }, { "uniprot_ac": "A0A8V0XDR5", "gene_name": "IRAK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XDR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XDR5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XDR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XDR5" } ] } ] }, { "uniprot_ac": "A0A8V0XE48", "gene_name": "ROCK2", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XE48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XE48" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "A0A8V0XE48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XE48" } ] } ] }, { "uniprot_ac": "A0A8V0XEA3", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XEA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEA3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XEA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEA3" } ] } ] }, { "uniprot_ac": "A0A8V0XFW1", "gene_name": "SGK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XFW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFW1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XFW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFW1" } ] } ] }, { "uniprot_ac": "A0A8V0XFX2", "gene_name": "NEK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XFX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFX2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XFX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFX2" } ] } ] }, { "uniprot_ac": "A0A8V0XG21", "gene_name": "LOC107050335", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XG21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XG21" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XG21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XG21" } ] } ] }, { "uniprot_ac": "A0A8V0XI18", "gene_name": "ATM", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XI18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XI18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XI18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XI18" } ] } ] }, { "uniprot_ac": "A0A8V0XKG0", "gene_name": "NEK9", "activity": [ { "ec_number": "2.7.11.38", "activity": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XKG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XKG0" } ] }, { "ec_number": "2.7.11.38", "activity": "", "evidence": [ { "id": "A0A8V0XKG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XKG0" } ] } ] }, { "uniprot_ac": "A0A8V0XLV6", "gene_name": "MAPK10", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XLV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLV6" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0XLV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLV6" } ] } ] }, { "uniprot_ac": "A0A8V0XMT1", "gene_name": "MOS", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XMT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMT1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XMT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMT1" } ] } ] }, { "uniprot_ac": "A0A8V0XMX8", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMX8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMX8" } ] } ] }, { "uniprot_ac": "A0A8V0XND6", "gene_name": "RIOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XND6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XND6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XND6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XND6" } ] } ] }, { "uniprot_ac": "A0A8V0XNJ2", "gene_name": "CDK8", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] } ] }, { "uniprot_ac": "A0A8V0XNK8", "gene_name": "PRKCQ", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XNK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNK8" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0XNK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNK8" } ] } ] }, { "uniprot_ac": "A0A8V0XQ14", "gene_name": "PLK4", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQ14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ14" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A8V0XQ14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ14" } ] } ] }, { "uniprot_ac": "A0A8V0XQ97", "gene_name": "CDK14", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQ97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ97" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0XQ97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ97" } ] } ] }, { "uniprot_ac": "A0A8V0XQQ4", "gene_name": "NME7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQQ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQQ4" } ] } ] }, { "uniprot_ac": "A0A8V0XQS0", "gene_name": "STK24", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQS0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XQS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQS0" } ] } ] }, { "uniprot_ac": "A0A8V0XS42", "gene_name": "MAP3K4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XS42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XS42" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0XS42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XS42" } ] } ] }, { "uniprot_ac": "A0A8V0XU71", "gene_name": "MYO3A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XU71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU71" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XU71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU71" } ] } ] }, { "uniprot_ac": "A0A8V0XU96", "gene_name": "PRKD1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XU96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU96" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0XU96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU96" } ] } ] }, { "uniprot_ac": "A0A8V0XUM6", "gene_name": "LATS1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XUM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XUM6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XUM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XUM6" } ] } ] }, { "uniprot_ac": "A0A8V0XW11", "gene_name": "RPS6KA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XW11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW11" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XW11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW11" } ] } ] }, { "uniprot_ac": "A0A8V0XW29", "gene_name": "CDKL2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XW29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW29" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0XW29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW29" } ] } ] }, { "uniprot_ac": "A0A8V0XXB8", "gene_name": "MAPK15", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XXB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXB8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0XXB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXB8" } ] } ] }, { "uniprot_ac": "A0A8V0Y074", "gene_name": "NEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y074", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y074" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y074", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y074" } ] } ] }, { "uniprot_ac": "A0A8V0Y241", "gene_name": "LOC426385", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y241", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y241" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y241", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y241" } ] } ] }, { "uniprot_ac": "A0A8V0Y2I5", "gene_name": "CDK7", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] } ] }, { "uniprot_ac": "A0A8V0Y3D1", "gene_name": "LRRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y3D1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3D1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y3D1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3D1" } ] } ] }, { "uniprot_ac": "A0A8V0Y3L2", "gene_name": "MLK4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y3L2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3L2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0Y3L2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3L2" } ] } ] }, { "uniprot_ac": "A0A8V0Y457", "gene_name": "PRPF4B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y457", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y457" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y457", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y457" } ] } ] }, { "uniprot_ac": "A0A8V0Y4L8", "gene_name": "HUNK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y4L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y4L8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y4L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y4L8" } ] } ] }, { "uniprot_ac": "A0A8V0Y6K1", "gene_name": "MAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6K1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6K1" } ] } ] }, { "uniprot_ac": "A0A8V0Y7C3", "gene_name": "DAPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y7C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7C3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y7C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7C3" } ] } ] }, { "uniprot_ac": "A0A8V0Y823", "gene_name": "SRPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y823", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y823" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y823", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y823" } ] } ] }, { "uniprot_ac": "A0A8V0Y8X9", "gene_name": "PRKACA", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y8X9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8X9" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0A8V0Y8X9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8X9" } ] } ] }, { "uniprot_ac": "A0A8V0Y935", "gene_name": "MAST4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y935", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y935" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y935", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y935" } ] } ] }, { "uniprot_ac": "A0A8V0Y955", "gene_name": "PAK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y955", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y955" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y955", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y955" } ] } ] }, { "uniprot_ac": "A0A8V0Y9Q1", "gene_name": "LOC107055388", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y9Q1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9Q1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y9Q1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9Q1" } ] } ] }, { "uniprot_ac": "A0A8V0YCV9", "gene_name": "SIK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YCV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YCV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCV9" } ] } ] }, { "uniprot_ac": "A0A8V0YCY4", "gene_name": "AURKB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YCY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YCY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY4" } ] } ] }, { "uniprot_ac": "A0A8V0YCY8", "gene_name": "RIOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YCY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YCY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY8" } ] } ] }, { "uniprot_ac": "A0A8V0YDH4", "gene_name": "ALPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YDH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDH4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YDH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDH4" } ] } ] }, { "uniprot_ac": "A0A8V0YF83", "gene_name": "WNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YF83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF83" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YF83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF83" } ] } ] }, { "uniprot_ac": "A0A8V0YFH4", "gene_name": "NRK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFH4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YFH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFH4" } ] } ] }, { "uniprot_ac": "A0A8V0YFL1", "gene_name": "CDK19", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0YFL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL1" } ] } ] }, { "uniprot_ac": "A0A8V0YFP8", "gene_name": "RIPK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFP8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YFP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFP8" } ] } ] }, { "uniprot_ac": "A0A8V0YFR6", "gene_name": "TNIK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFR6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YFR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFR6" } ] } ] }, { "uniprot_ac": "A0A8V0YGW2", "gene_name": "STK32B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YGW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGW2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YGW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGW2" } ] } ] }, { "uniprot_ac": "A0A8V0YHH2", "gene_name": "STK38L", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YHH2", "database": "UniProtKB", "url": 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"https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] } ] }, { "uniprot_ac": "A0A8V0YJP9", "gene_name": "RIOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YJP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YJP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP9" } ] } ] }, { "uniprot_ac": "A0A8V0YK18", "gene_name": "CDC42BPB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YK18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YK18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK18" } ] } ] }, { "uniprot_ac": "A0A8V0YKK3", "gene_name": "MAP4K4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKK3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKK3" } ] } ] }, { "uniprot_ac": "A0A8V0YLV1", "gene_name": "MARK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YLV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLV1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YLV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLV1" } ] } ] }, { "uniprot_ac": "A0A8V0YM22", "gene_name": "MYO3AL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YM22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM22" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YM22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM22" } ] } ] }, { "uniprot_ac": "A0A8V0YM96", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YM96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM96" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YM96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM96" } ] } ] }, { "uniprot_ac": "A0A8V0YMB3", "gene_name": "STK32A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMB3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMB3" } ] } ] }, { "uniprot_ac": "A0A8V0YMN5", "gene_name": "BRAF", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YMN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YMN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN5" } ] } ] }, { "uniprot_ac": "A0A8V0YNI5", "gene_name": "NIM1K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YNI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNI5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YNI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNI5" } ] } ] }, { "uniprot_ac": "A0A8V0YRC9", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] } ] }, { "uniprot_ac": "A0A8V0YRN4", "gene_name": "GAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRN4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YRN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRN4" } ] } ] }, { "uniprot_ac": "A0A8V0YSH3", "gene_name": "RPS6KA6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YSH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSH3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YSH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSH3" } ] } ] }, { "uniprot_ac": "A0A8V0YTI1", "gene_name": "TSSK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTI1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTI1" } ] } ] }, { "uniprot_ac": "A0A8V0YTL9", "gene_name": "VRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTL9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTL9" } ] } ] }, { "uniprot_ac": "A0A8V0YTN5", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTN5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTN5" } ] } ] }, { "uniprot_ac": "A0A8V0YTP2", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTP2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTP2" } ] } ] }, { "uniprot_ac": "A0A8V0YXZ5", "gene_name": "CDC42BPA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YXZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXZ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YXZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXZ5" } ] } ] }, { "uniprot_ac": "A0A8V0YYX2", "gene_name": "PAK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YYX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYX2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YYX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYX2" } ] } ] }, { "uniprot_ac": "A0A8V0YYZ3", "gene_name": "SPEG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YYZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYZ3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YYZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYZ3" } ] } ] }, { "uniprot_ac": "A0A8V0YZ74", "gene_name": "MAP2K5", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZ74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZ74" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V0YZ74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZ74" } ] } ] }, { "uniprot_ac": "A0A8V0YZF2", "gene_name": "PAK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZF2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YZF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZF2" } ] } ] }, { "uniprot_ac": "A0A8V0YZK0", "gene_name": "MAP3K6", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZK0" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0YZK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZK0" } ] } ] }, { "uniprot_ac": "A0A8V0YZM1", "gene_name": "MOK", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] }, { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] } ] }, { "uniprot_ac": "A0A8V0YZV9", "gene_name": "ATR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YZV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZV9" } ] } ] }, { "uniprot_ac": "A0A8V0YZY4", "gene_name": "SBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZY4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YZY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZY4" } ] } ] }, { "uniprot_ac": "A0A8V0Z124", "gene_name": "VRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z124", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z124" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z124", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z124" } ] } ] }, { "uniprot_ac": "A0A8V0Z157", "gene_name": "MARK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] } ] }, { "uniprot_ac": "A0A8V0Z1X0", "gene_name": "MAP4K3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z1X0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1X0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z1X0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1X0" } ] } ] }, { "uniprot_ac": "A0A8V0Z283", "gene_name": "MARK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] } ] }, { "uniprot_ac": "A0A8V0Z2E3", "gene_name": "PDIK1L", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z2E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2E3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z2E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2E3" } ] } ] }, { "uniprot_ac": "A0A8V0Z2Z3", "gene_name": "AAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z2Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2Z3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z2Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2Z3" } ] } ] }, { "uniprot_ac": "A0A8V0Z466", "gene_name": "MAP3K19", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z466", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z466" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z466", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z466" } ] } ] }, { "uniprot_ac": "A0A8V0Z6K4", "gene_name": "PIK3R4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z6K4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6K4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z6K4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6K4" } ] } ] }, { "uniprot_ac": "A0A8V0Z6T1", "gene_name": "ERN2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": 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"activity": "", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] } ] }, { "uniprot_ac": "A0A8V0ZD48", "gene_name": "PRKCE", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD48" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0ZD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD48" } ] } ] }, { "uniprot_ac": "A0A8V0ZD60", "gene_name": "STK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD60", "database": 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O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] }, { "ec_number": "2.7.1.150", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] }, { "ec_number": "2.7.1.150", "activity": "", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] } ] }, { "uniprot_ac": "A0A8V0ZNP7", "gene_name": "SGK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", 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"url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZQJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQJ2" } ] } ] }, { "uniprot_ac": "A0A8V0ZQT5", "gene_name": "SLC13A3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZQT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQT5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZQT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQT5" } ] } ] }, { "uniprot_ac": "A0A8V0ZRX1", "gene_name": "SETD6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZRX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRX1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZRX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRX1" } ] }, { "ec_number": "2.1.1.-", "activity": "", "evidence": [ { "id": "A0A8V0ZRX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRX1" } ] } ] }, { "uniprot_ac": "A0A8V0ZSB4", "gene_name": "SIK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZSB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSB4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZSB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSB4" } ] } ] }, { "uniprot_ac": "A0A8V0ZSP4", "gene_name": "PKN2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] }, { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] } ] }, { "uniprot_ac": "A0A8V0ZT63", "gene_name": "STK25", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZT63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT63" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZT63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT63" } ] } ] }, { "uniprot_ac": "A0A8V0ZUC6", "gene_name": "PAK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUC6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUC6" } ] } ] }, { "uniprot_ac": "A0A8V0ZUL0", "gene_name": "PASK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUL0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUL0" } ] } ] }, { "uniprot_ac": "A0A8V0ZUU8", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU8" } ] } ] }, { "uniprot_ac": "A0A8V0ZUU9", "gene_name": "MKNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU9" } ] } ] }, { "uniprot_ac": "A0A8V0ZWC7", "gene_name": "EIF2AK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZWC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWC7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZWC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWC7" } ] } ] }, { "uniprot_ac": "A0A8V0ZWW1", "gene_name": "MAP3K12", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZWW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWW1" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0ZWW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWW1" } ] } ] }, { "uniprot_ac": "A0A8V0ZXQ9", "gene_name": "PRKG1", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZXQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXQ9" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0A8V0ZXQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXQ9" } ] } ] }, { "uniprot_ac": "A0A8V0ZYU6", "gene_name": "TNNI3K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZYU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYU6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZYU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYU6" } ] } ] }, { "uniprot_ac": "A0A8V0ZZE4", "gene_name": "OBSCN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZZE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZE4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZZE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZE4" } ] } ] }, { "uniprot_ac": "A0A8V0ZZK5", "gene_name": "STK38", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZZK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZK5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZZK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZK5" } ] } ] }, { "uniprot_ac": "A0A8V0ZZV3", "gene_name": "MYO3B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZZV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZV3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZZV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZV3" } ] } ] }, { "uniprot_ac": "A0A8V1A069", "gene_name": "TESK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A069", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A069" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1A069", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A069" } ] } ] }, { "uniprot_ac": "A0A8V1A0W4", "gene_name": "ULK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A0W4", "database": 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} ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A1P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1P3" } ] } ] }, { "uniprot_ac": "A0A8V1A1Y7", "gene_name": "CDK2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A1Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1Y7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V1A1Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1Y7" } ] } ] }, { "uniprot_ac": "A0A8V1A2T9", "gene_name": "MAP3K14", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A2T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2T9" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V1A2T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2T9" } ] } ] }, { "uniprot_ac": "A0A8V1A3T8", "gene_name": "MAST3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A3T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3T8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A3T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3T8" } ] } ] }, { "uniprot_ac": "A0A8V1A4A1", "gene_name": "CAMKK2", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4A1" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1A4A1", "database": "UniProtKB", "url": 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"uniprot_ac": "A0A8V1A4V7", "gene_name": "HIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A4V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V7" } ] } ] }, { "uniprot_ac": "A0A8V1A513", "gene_name": "DAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A513" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A513" } ] } ] }, { "uniprot_ac": "A0A8V1A675", "gene_name": "CSNK1G2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A675", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A675" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A675", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A675" } ] } ] }, { "uniprot_ac": "A0A8V1A7E0", "gene_name": "DYRK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1A7E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E0" } ] } ] }, { "uniprot_ac": "A0A8V1A7E9", "gene_name": "SIK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E9" } ] } ] }, { "uniprot_ac": "A0A8V1A7M0", "gene_name": "STK39", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M0" } ] } ] }, { "uniprot_ac": "A0A8V1A7P9", "gene_name": "DCAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] } ] }, { "uniprot_ac": "A0A8V1A9S5", "gene_name": "NUAK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A9S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9S5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A9S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9S5" } ] } ] }, { "uniprot_ac": "A0A8V1ABF3", "gene_name": "PRKAA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] } ] }, { "uniprot_ac": "A0A8V1ABP4", "gene_name": "DSTYK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP4" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1ABP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP4" } ] } ] }, { "uniprot_ac": "A0A8V1ABR8", "gene_name": "CAMK4L", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR8" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1ABR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR8" } ] } ] }, { "uniprot_ac": "A0A8V1AC40", "gene_name": "CDK18", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AC40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC40" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V1AC40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC40" } ] } ] }, { "uniprot_ac": "A0A8V1ACB5", "gene_name": "MAPK13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACB5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1ACB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACB5" } ] } ] }, { "uniprot_ac": "A0A8V1ACF6", "gene_name": "PIM1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF6" } ] } ] }, { "uniprot_ac": "A0A8V1ACK0", "gene_name": "MAPKAPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK0" } ] } ] }, { "uniprot_ac": "A0A8V1ACW2", "gene_name": "WNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACW2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACW2" } ] } ] }, { "uniprot_ac": "A0A8V1ADF0", "gene_name": "MAP2K2", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF0" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V1ADF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF0" } ] } ] }, { "uniprot_ac": "A0A8V1ADN9", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADN9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1ADN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADN9" } ] } ] }, { "uniprot_ac": "A0A8V1ADT4", "gene_name": "MKNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADT4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ADT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADT4" } ] } ] }, { "uniprot_ac": "A0A8V1AE45", "gene_name": "ERN1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AE45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE45" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AE45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE45" } ] } ] }, { "uniprot_ac": "A0A8V1AEH4", "gene_name": "STK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEH4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEH4" } ] } ] }, { "uniprot_ac": "A0A8V1AFS4", "gene_name": "STKLD1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AFS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFS4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AFS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFS4" } ] } ] }, { "uniprot_ac": "A0A8V1AG70", "gene_name": "LOC100857512", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AG70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG70" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AG70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG70" } ] } ] }, { "uniprot_ac": "A0A8V1AH12", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AH12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH12" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AH12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH12" } ] } ] }, { "uniprot_ac": "A0A8V1AHA8", "gene_name": "NEK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AHA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHA8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AHA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHA8" } ] } ] }, { "uniprot_ac": "A0A8V1AIY7", "gene_name": "AATK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AIY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AIY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIY7" } ] } ] }, { "uniprot_ac": "A0A8V1AJA4", "gene_name": "RPS6KB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AJA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJA4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AJA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJA4" } ] } ] }, { "uniprot_ac": "A0A8V1AKW4", "gene_name": "MAP2K4", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AKW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKW4" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V1AKW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKW4" } ] } ] }, { "uniprot_ac": "A0A8V1AM12", "gene_name": "GSG2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AM12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM12" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AM12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM12" } ] } ] }, { "uniprot_ac": "A0A8V1AMK5", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AMK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V1AMK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK5" } ] } ] }, { "uniprot_ac": "A0A8V1AMQ2", "gene_name": "CAMKK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AMQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ2" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1AMQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ2" } ] } ] }, { "uniprot_ac": "A0A8V1AP60", "gene_name": "KSR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AP60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AP60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP60" } ] } ] }, { "uniprot_ac": "E1BQN6", "gene_name": "PRKCZ", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQN6" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1BQN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQN6" } ] } ] }, { "uniprot_ac": "E1BQV7", "gene_name": "SLK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQV7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BQV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQV7" } ] } ] }, { "uniprot_ac": "E1BUG0", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] } ] }, { "uniprot_ac": "E1BW33", "gene_name": "SMG1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BW33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BW33" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BW33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BW33" } ] } ] }, { "uniprot_ac": "E1BWA3", "gene_name": "PRKCI", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BWA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWA3" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1BWA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWA3" } ] } ] }, { "uniprot_ac": "E1BWT0", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BWT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWT0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BWT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWT0" } ] } ] }, { "uniprot_ac": "E1BX69", "gene_name": "EIF2AK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BX69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BX69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BX69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BX69" } ] } ] }, { "uniprot_ac": "E1BY69", "gene_name": "PIM3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BY69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BY69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY69" } ] } ] }, { "uniprot_ac": "E1BYH2", "gene_name": "TAOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BYH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYH2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BYH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYH2" } ] } ] }, { "uniprot_ac": "E1C093", "gene_name": "PIK3CG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] } ] }, { "uniprot_ac": "E1C2I2", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C2I2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2I2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C2I2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2I2" } ] } ] }, { "uniprot_ac": "E1C581", "gene_name": "TBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C581", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C581" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C581", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C581" } ] } ] }, { "uniprot_ac": "E1C6T4", "gene_name": "PRKD3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C6T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C6T4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1C6T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C6T4" } ] } ] }, { "uniprot_ac": "E1C764", "gene_name": "BMP2K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C764", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C764" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C764", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C764" } ] } ] }, { "uniprot_ac": "E1C848", "gene_name": "MAP3K8", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C848", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C848" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1C848", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C848" } ] } ] }, { "uniprot_ac": "F1NA68", "gene_name": "CDK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NA68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NA68" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1NA68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NA68" } ] } ] }, { "uniprot_ac": "F1NB57", "gene_name": "PLK2", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NB57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NB57" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "F1NB57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NB57" } ] } ] }, { "uniprot_ac": "F1NBT0", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NBT0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NBT0" } ] } ] }, { "uniprot_ac": "F1NCX7", "gene_name": "PLK1", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NCX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCX7" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "F1NCX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCX7" } ] } ] }, { "uniprot_ac": "F1NCY7", "gene_name": "MAPKAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NCY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NCY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCY7" } ] } ] }, { "uniprot_ac": "F1NJH1", "gene_name": "PRKCH", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NJH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJH1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1NJH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJH1" } ] } ] }, { "uniprot_ac": "F1NKW3", "gene_name": "MAP3K15", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NKW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NKW3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1NKW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NKW3" } ] } ] }, { "uniprot_ac": "F1NLR7", "gene_name": "CLK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NLR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLR7" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "F1NLR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLR7" } ] } ] }, { "uniprot_ac": "F1NUX4", "gene_name": "MTOR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NUX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NUX4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NUX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NUX4" } ] } ] }, { "uniprot_ac": "F1NVF2", "gene_name": "MAP2K6", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NVF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVF2" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "F1NVF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVF2" } ] } ] }, { "uniprot_ac": "F1P011", "gene_name": "CAMK2A", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1P011", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P011" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F1P011", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P011" } ] } ] }, { "uniprot_ac": "F1P356", "gene_name": "NUAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1P356", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P356" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1P356", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P356" } ] } ] }, { "uniprot_ac": "F1P4G3", "gene_name": "HIPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1P4G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P4G3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1P4G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P4G3" } ] } ] }, { "uniprot_ac": "P05625", "gene_name": "RAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05625", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05625" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P05625", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05625" } ] } ] }, { "uniprot_ac": "P10741", "gene_name": "MOS", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P10741", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P10741" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P10741", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P10741" } ] } ] }, { "uniprot_ac": "P13863", "gene_name": "CDK1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13863" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13863" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13863" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13863" } ] } ] }, { "uniprot_ac": "P18652", "gene_name": "RPS6KA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P18652", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18652" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P18652", "database": 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"name": "AP-3 complex subunit delta", "type": "synonym", "evidence": [ { "id": "A0A8V1AAZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAZ3/entry#names_and_taxonomy" } ] }, { "name": "Adaptor-related protein complex 3 subunit delta-1", "type": "synonym", "evidence": [ { "id": "A0A8V1AAZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAZ3/entry#names_and_taxonomy" } ] }, { "name": "Delta-adaptin", "type": "synonym", "evidence": [ { "id": "A0A8V1AAZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAZ3/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. Involved in process of CD8+ T-cell and NK cell degranulation. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAZ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAZ3#function" }, { "database": "UniProtKB", "id": "ARBA00055970", "url": "https://www.uniprot.org/uniprotkb/ARBA00055970#function" }, { "database": "UniProtKB", "id": "A0A8V1AI49", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI49#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAZ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAZ3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "AP3D1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAZ3", "locus": { "chromosome": "28", "start_pos": 2548428, "end_pos": 2521831, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027897", "url": "https://www.ensembl.org/id/ENSGALG00010027897" } ] } } ], "crossref": [ { "id": "A0A8V1AAZ3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AAZ3", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR002553", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002553", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010474", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010474", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017105", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017105", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058898", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058898", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AAZ3", "url": "https://www.orthodb.org/?gene=A0A8V1AAZ3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AI49", "url": "https://www.orthodb.org/?gene=A0A8V1AI49", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22781", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22781", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22781:SF12", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22781:SF12", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01602", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01602", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF06375", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06375", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF26171", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26171", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1AAZ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAZ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AAZ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAZ3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AI49", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI49", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AI49-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI49-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MALKMVKGSIDRMFDKNLQDLVRGIRNHKEDEAKYISQCIDEIKQELKQDNIAVKANAVCKLTYLQMLGYDISWAAFNIIEVMSASKFTFKRIGYLAASQCFHEGTDVIMLTTNQIRKDLSSPNQYDTGVALTGLSCFVTPDLARDLANDIMTLMSHTKPYIRKKAVLIMYKVFLKYPESLRPAFPRLKEKLEDPDPGVQSAAVNVICELARRNPKNYLSLAPLFFKLMTSSTNNWVLIKIIKLFGALTPLEPRLGKKLIEPLTNLIHSTSAMSLLYECVNTVIAVLISLSSGMPNHSASIQLCVQKLRILIEDSDQNLKYLGLLAMSKILKTHPKSVQSHKDLILQCLDDKDESIRLRALDLLYGMVSKKNLMEIVKKLMIHVDKAEGTTYRDELLTKIIDICSQSNYQYITNFEWYISILVELTRLEGTRHGHLIAAQMLDVAIRVKAIRKFAVSQMAMLLDNAHLIASNTQRNGICEVLYAAAWICGEFSEHLEEANQTLEAMLRPKVTTLPGHIQAVYVQNMVKLYASILQQKEQAGEKEAAQEITQLMIERLPQFVQSADLEVQERASCILQLIKYIQKLQVKEVPVAEEVIALFAGELNPVAPKAQKKVPVPEGLDLDAWINEPPSDSESEDEKPKTIFHDEEQRHSKPRHPEMDEEELARRREARKQEQANNPFYIKSSPSPQKRYQDTPGVEHIPVVQIDLSVPLKVPGMPMSDQYVKLEEERRHKQKLEKDKKKKKQKKEKRGKHHRHNSLHTESEEDIAPAHHVDIITEEMPENALPSDEDDKDPNDPYKALDIDLDKPLADSEKLPVQRHRNAEALKTPESEVPPVEKKSKKPKKKEKKHKEKEKDKGKKKEKEKKVVEEEEEEKKEEDLDFWLSTAPPPGSAAQPQEEEEEDEGKKSSKHKKKKHKKEKEEKSKDKKKSKKKHHHSEEEMAESVQNGTLDDEPLPPMSSYRLLAENPYIKTTYDIQGNLQNDSQVTVSVIFENKSTSFLKSMELNVLDSLNTKMLRPEGSSVHDGIPVPFQLPPGISNEAQFVFTLQSIVMAQKLKGTLSFIVKNDEGSTHEKLDFKLHFSCASYLITTPCYSDAFAKLLESGDLHMSSIKVDGISISFQHLLAKICFHHHFSVVERVDSCASMYSRSIQGHHVCLLVKKGENSVSIDGKCSDPTLLSNLLDEMKETLSKC", 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"length": 1193, "header": "tr|A0A8V1AAZ3-1|A0A8V1AAZ3_CHICK Isoform 1 of AP-3 complex subunit delta-1 OS=Gallus gallus OX=9031 GN=AP3D1 PE=1 SV=1 CANONICAL=A0A8V1AAZ3-1" }, "locus": { "chromosome": "28", "start_pos": 2547438, "end_pos": 2522088, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067627.1", "url": "https://www.ensembl.org/id/ENSGALT00010067627.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041370.1", "url": "https://www.ensembl.org/id/ENSGALP00010041370.1" } ] } }, { "isoform_ac": "A0A8V1AI49-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAZ3/entry#A0A8V1AI49-1", "sequence": { "sequence": "MALKMVKGSIDRMFDKNLQDLVRGIRNHKEDEAKYISQCIDEIKQELKQDNIAVKANAVCKLTYLQMLGYDISWAAFNIIEVMSASKFTFKRIGYLAASQCFHEGTDVIMLTTNQIRKDLSSPNQYDTGVALTGLSCFVTPDLARDLANDIMTLMSHTKPYIRKKAVLIMYKVFLKYPESLRPAFPRLKEKLEDPDPGVQSAAVNVICELARRNPKNYLSLAPLFFKLMTSSTNNWVLIKIIKLFGALTPLEPRLGKKLIEPLTNLIHSTSAMSLLYECVNTVIAVLISLSSGMPNHSASIQLCVQKLRILIEDSDQNLKYLGLLAMSKILKTHPKSVQSHKDLILQCLDDKDESIRLRALDLLYGMVSKKNLMEIVKKLMIHVDKAEGTTYRDELLTKIIDICSQSNYQYITNFEWYISILVELTRLEGTRHGHLIAAQMLDVAIRVKAIRKFAVSQMAMLLDNAHLIASNTQRNGICEVLYAAAWICGEFSEHLEEANQTLEAMLRPKVTTLPGHIQAVYVQNMVKLYASILQQKEQAGEKEAAQEITQLMIERLPQFVQSADLEVQERASCILQLIKYIQKLQVKEVPVAEEVIALFAGELNPVAPKAQKKVPVPEGLDLDAWINEPPSDSESEDEKPKTIFHDEEQRHSKPRHPEMDEEELARRREARKQEQANNPFYIKSSPSPQKRYQDTPGVEHIPVVQIDLSVPLKVPGMPMSDQYVKLEEERRHKQKLEKDKKKKKQKKEKRGKHHRHNSLHTESEEDIAPAHHVDIITEEMPENALPSDEDDKDPNDPYKALDIDLDKPLADSEKLPVQRHRNAEALKTPESEVPPVEKKSKKPKKKEKKHKEKEKDKGKKKEKEKKHKKEKEEKSKDKKKSKKKHHHSEEEMAESVQNGTLDDEPLPPMSSYRLLAENPYIKTTYDIQGNLQNDSQVTVSVIFENKSTSFLKSMELNVLDSLNTKMLRPEGSSVHDGIPVPFQLPPGISNEAQFVFTLQSIVMAQKLKGTLSFIVKNDEGSTHEKLDFKLHFSCASYLITTPCYR", "length": 1046, "header": "tr|A0A8V1AI49-1|A0A8V1AAZ3_CHICK Computationally mapped isoform of AP-3 complex subunit delta-1 OS=Gallus gallus OX=9031 GN=AP3D1 PE=1 SV=1 CANONICAL=A0A8V1AAZ3-1" }, "locus": { "chromosome": "28", "start_pos": 2546313, "end_pos": 2522088, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067621.1", "url": "https://www.ensembl.org/id/ENSGALT00010067621.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041364.1", "url": "https://www.ensembl.org/id/ENSGALP00010041364.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 10, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAZ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAZ3" } ], "pmid": "" }, { "name": "endosome", "id": "GO:0005768", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005768", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAZ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAZ3" } ], "pmid": "" }, { "name": "cytoplasmic vesicle membrane", "id": "GO:0030659", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030659", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAZ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAZ3" } ], "pmid": "" }, { "name": "AP-3 adaptor complex", "id": "GO:0030123", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030123", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAZ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAZ3" } ], "pmid": "" }, { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAZ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAZ3" } ], "pmid": "" }, { "name": "terminal bouton", "id": "GO:0043195", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043195", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAZ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAZ3" } ], "pmid": "" }, { "name": "postsynapse", "id": "GO:0098794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098794", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAZ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAZ3" } ], "pmid": "" }, { "name": "endosome membrane", "id": "GO:0010008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010008", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAZ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAZ3" } ], "pmid": "" }, { "name": "presynaptic endosome", "id": "GO:0098830", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098830", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAZ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAZ3" } ], "pmid": "" }, { "name": "axon cytoplasm", "id": "GO:1904115", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904115", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAZ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAZ3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 12, "go_terms": [ { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAZ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAZ3" } ], "pmid": "" }, { "name": "vesicle-mediated transport", "id": "GO:0016192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016192", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAZ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAZ3" } ], "pmid": "" }, { "name": "lysosomal transport", "id": "GO:0007041", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007041", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAZ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAZ3" } ], "pmid": "" }, { "name": "synaptic vesicle budding from endosome", "id": "GO:0016182", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016182", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAZ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAZ3" } ], "pmid": "" }, { "name": "endosome to melanosome transport", "id": "GO:0035646", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035646", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAZ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAZ3" } ], "pmid": "" }, { "name": "anterograde synaptic vesicle transport", "id": "GO:0048490", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048490", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAZ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAZ3" } ], "pmid": "" }, { "name": "synaptic vesicle membrane organization", "id": "GO:0048499", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048499", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAZ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAZ3" } ], "pmid": "" }, { "name": "protein localization to membrane", "id": "GO:0072657", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072657", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAZ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAZ3" } ], "pmid": "" }, { "name": "neurotransmitter receptor transport, postsynaptic endosome to lysosome", "id": "GO:0098943", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098943", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAZ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAZ3" } ], "pmid": "" }, { "name": "protein targeting to vacuole", "id": "GO:0006623", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006623", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAZ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAZ3" } ], "pmid": "" }, { "name": "Golgi to vacuole transport", "id": "GO:0006896", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006896", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAZ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAZ3" } ], "pmid": "" }, { "name": "zinc ion import into lysosome", "id": "GO:0140916", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140916", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAZ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAZ3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 296, "end_pos": 298, "annotation": "n_glycosylation_sequon" }, { "start_pos": 500, "end_pos": 502, "annotation": "n_glycosylation_sequon" }, { "start_pos": 948, "end_pos": 950, "annotation": "n_glycosylation_sequon" }, { "start_pos": 983, "end_pos": 985, "annotation": "n_glycosylation_sequon" }, { "start_pos": 995, "end_pos": 997, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AAZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAZ3" }, { "id": "SM01354", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM01354" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "AP-3 complex subunit delta", "eco_id": "ECO_0000259", "start_pos": 660, "end_pos": 807, "start_aa": "Met", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 296, "end_pos": 298 }, { "start_pos": 500, "end_pos": 502 }, { "start_pos": 948, "end_pos": 950 }, { "start_pos": 983, "end_pos": 985 }, { "start_pos": 995, "end_pos": 997 } ] }, "class_list": [], "section_stats": [ { 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"sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1ACK0-1", "uniprot_ac": "A0A8V1ACK0", "uniprot_id": "A0A8V1ACK0_CHICK", "mass": { "chemical_mass": 47636.0, "monoisotopic_mass": 47636.0 }, "refseq": {}, "gene_names": [ { "name": "MAPKAPK3", "type": "recommended", "evidence": [ { "id": "A0A8V1ACK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK0" } ] } ], "protein_names": [ { "name": "non-specific serine/threonine protein kinase", "type": "recommended", "evidence": [ { "id": "A0A8V1ACK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK0/entry#names_and_taxonomy" } ] }, { "name": "2.7.11.1", "type": "synonym", "evidence": [ { "id": "A0A8V1ACK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK0/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACK0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MAPKAPK3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK0", "locus": { "chromosome": "12", "start_pos": 1988947, "end_pos": 1944583, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028146", "url": "https://www.ensembl.org/id/ENSGALG00010028146" } ] } } ], "crossref": [ { "id": "A0A8V1ACK0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1ACK0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000002283", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000002283", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd14172", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14172", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "415917", "url": "https://www.ncbi.nlm.nih.gov/gene/415917", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008271", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008271", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017441", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017441", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027442", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027442", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:415917", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415917", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PSPEWDC", "url": "https://omabrowser.org/oma/group/PSPEWDC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2U1E9", "url": "https://www.orthodb.org/?gene=A0A3Q2U1E9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ACK0", "url": "https://www.orthodb.org/?gene=A0A8V1ACK0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AJI9", "url": "https://www.orthodb.org/?gene=A0A8V1AJI9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BT35", "url": "https://www.orthodb.org/?gene=E1BT35", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24347", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24347", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00069", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00069", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "17989", "url": "https://www.rhea-db.org/rhea/17989", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "46608", "url": "https://www.rhea-db.org/rhea/46608", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q2U1E9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U1E9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2U1E9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U1E9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ACK0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ACK0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJI9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJI9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJI9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJI9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BT35", "url": "https://www.uniprot.org/uniprotkb/E1BT35", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BT35-1", "url": "https://www.uniprot.org/uniprotkb/E1BT35-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQHSGLDGGRCVSGPSAPGDGAEGSPGGRRGGRGLSPAMERDGGEQESQPESHVESRSGVKPVPGGAAHVKLEIKKHAVTDDYKLSKRVLGLGINGKVLECFHKETGQKCALKLLYDNPKARLEVEYHWRASGCPHIVHILDVYENMHHGKRCLLIVMECMEGGELFSRIQERGDQAFTEREASEIMRDIGTAIQYLHSMNIAHRDVKPENLLYTSKEKDTVLKLTDFGFAKETTVQNALQTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVITYILLCGFPPFYSNTGQAISPGMKRRIRMGQYGFPNPEWAEVSEEAKQLIRHLLKTDPTERMTISQFMNHPWINRSMAVPPTPLHTARVLQEDKDHWDEVKEEMTSALATMRVDYDQVKIKDLKTSNNRLLNKRRKKQKQSGTSSAAPGCNNQ", "length": 425, "header": "tr|A0A8V1ACK0-1|A0A8V1ACK0_CHICK Isoform 1 of non-specific serine/threonine protein kinase OS=Gallus gallus OX=9031 GN=MAPKAPK3 PE=1 SV=1 CANONICAL=A0A8V1ACK0-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2U1E9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK0/entry#A0A3Q2U1E9-1", "sequence": { "sequence": "MERDGGEQESQPESHVESRSGVKPVPGGAAHVKLEIKKHAVTDDYKLSKRVLGLGINGKVLECFHKETGQKCALKLLYDNPKARLEVEYHWRASGCPHIVHILDVYENMHHGKRCLLIVMECMEGGELFSRIQERGDQAFTEREASEIMRDIGTAIQYLHSMNIAHRDVKPENLLYTSKEKDTVLKLTDFGFAKETTVQNALQTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVITYILLCGFPPFYSNTGQAISPGMKRRIRMGQYGFPNPEWAEVSEEAKQLIRHLLKTDPTERMTISQFMNHPWINRSMAVPPTPLHTARVLQEDKDHWDEVKVPHLLFVLMAVECFLQSATIGQTKSCLQALTLSCWPLPGGDDQCFGYHEGGLRSGEN", "length": 392, "header": "tr|A0A3Q2U1E9-1|A0A8V1ACK0_CHICK Computationally mapped isoform of non-specific serine/threonine protein kinase OS=Gallus gallus OX=9031 GN=MAPKAPK3 PE=1 SV=1 CANONICAL=A0A8V1ACK0-1" }, "locus": { "chromosome": "12", "start_pos": 1987201, "end_pos": 1947436, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068198.1", "url": "https://www.ensembl.org/id/ENSGALT00010068198.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041941.1", "url": "https://www.ensembl.org/id/ENSGALP00010041941.1" } ] } }, { "isoform_ac": "A0A8V1ACK0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK0/entry#A0A8V1ACK0-1", "sequence": { "sequence": "MQHSGLDGGRCVSGPSAPGDGAEGSPGGRRGGRGLSPAMERDGGEQESQPESHVESRSGVKPVPGGAAHVKLEIKKHAVTDDYKLSKRVLGLGINGKVLECFHKETGQKCALKLLYDNPKARLEVEYHWRASGCPHIVHILDVYENMHHGKRCLLIVMECMEGGELFSRIQERGDQAFTEREASEIMRDIGTAIQYLHSMNIAHRDVKPENLLYTSKEKDTVLKLTDFGFAKETTVQNALQTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVITYILLCGFPPFYSNTGQAISPGMKRRIRMGQYGFPNPEWAEVSEEAKQLIRHLLKTDPTERMTISQFMNHPWINRSMAVPPTPLHTARVLQEDKDHWDEVKEEMTSALATMRVDYDQVKIKDLKTSNNRLLNKRRKKQKQSGTSSAAPGCNNQ", "length": 425, "header": "tr|A0A8V1ACK0-1|A0A8V1ACK0_CHICK Isoform 1 of non-specific serine/threonine protein kinase OS=Gallus gallus OX=9031 GN=MAPKAPK3 PE=1 SV=1 CANONICAL=A0A8V1ACK0-1" }, "locus": { "chromosome": "12", "start_pos": 1987301, "end_pos": 1944782, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068203.1", "url": "https://www.ensembl.org/id/ENSGALT00010068203.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041946.1", "url": "https://www.ensembl.org/id/ENSGALP00010041946.1" } ] } }, { "isoform_ac": "A0A8V1AJI9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK0/entry#A0A8V1AJI9-1", "sequence": { "sequence": "MERDGGEQESQPESHVESRSGVKPVPGGAAHVKLEIKKHAVTDDYKLSKRVLGLGINGKVLECFHKETGQKCALKLLYDNPKARLEVEYHWRASGCPHIVHILDVYENMHHGKRCLLIVMECMEGGELFSRIQERGDQAFTEREASEIMRDIGTAIQYLHSMNIAHRDVKVRSEAPEVLGPEKYDKSCDMWSLGVITYILLCGFPPFYSNTGQAISPGMKRRIRMGQYGFPNPEWAEVSEEAKQLIRHLLKTDPTERMTISQFMNHPWINRSMAVPPTPLHTARVLQEDKDHWDEVKEEMTSALATMRVDYDQVKIKDLKTSNNRLLNKRRKKQKQSGTSSAAPGCNNQ", "length": 349, "header": "tr|A0A8V1AJI9-1|A0A8V1ACK0_CHICK Computationally mapped isoform of non-specific serine/threonine protein kinase OS=Gallus gallus OX=9031 GN=MAPKAPK3 PE=1 SV=1 CANONICAL=A0A8V1ACK0-1" }, "locus": { "chromosome": "12", "start_pos": 1987301, "end_pos": 1947436, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068202.1", "url": "https://www.ensembl.org/id/ENSGALT00010068202.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041945.1", "url": "https://www.ensembl.org/id/ENSGALP00010041945.1" } ] } }, { "isoform_ac": "E1BT35-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK0/entry#E1BT35-1", "sequence": { "sequence": "MERDGGEQESQPESHVESRSGVKPVPGGAAHVKLEIKKHAVTDDYKLSKRVLGLGINGKVLECFHKETGQKCALKLLYDNPKARLEVEYHWRASGCPHIVHILDVYENMHHGKRCLLIVMECMEGGELFSRIQERGDQAFTEREASEIMRDIGTAIQYLHSMNIAHRDVKPENLLYTSKEKDTVLKLTDFGFAKETTVQNALQTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVITYILLCGFPPFYSNTGQAISPGMKRRIRMGQYGFPNPEWAEVSEEAKQLIRHLLKTDPTERMTISQFMNHPWINRSMAVPPTPLHTARVLQEDKDHWDEVKEEMTSALATMRVDYDQVKIKDLKTSNNRLLNKRRKKQKQSGTSSAAPGCNNQ", "length": 387, "header": "tr|E1BT35-1|A0A8V1ACK0_CHICK Computationally mapped isoform of non-specific serine/threonine protein kinase OS=Gallus gallus OX=9031 GN=MAPKAPK3 PE=1 SV=1 CANONICAL=A0A8V1ACK0-1" }, "locus": { "chromosome": "12", "start_pos": 1987301, "end_pos": 1947436, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068200.1", "url": "https://www.ensembl.org/id/ENSGALT00010068200.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041943.1", "url": "https://www.ensembl.org/id/ENSGALP00010041943.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 354, "start_aa": "Thr", "end_pos": 354, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr354", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:415917", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415917", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2M9B6-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "Mapkapk3", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDGEAAGEKGSLVPPPGALDGPTLGGAQALGVRREPKKYAVTDDYQLSKQVLGLGVNGKVLECYHRRTGQKCALKLLYDSPKARQEVDHHWQASGGPHIVRVLDVYENMHHGKRCLLIVMECMEGGELFSRIQERGDQAFTEREAAEIMRDIGTAIQFLHSQNIAHRDVKPENLLYTSKEKDAVLKLTDFGFAKETTQNALQTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGFPPFYSNTGQAISPGMKRRIRLGQYGFPKPEWSEVSEDAKQLIRLLLKTDPTERLTIMQFMNHPWINQSMVVPQTPLHTARVLQEDKDHWDEVKEEMTSALATMRVDYDQVKIKDLKTSNNRLLNKRRKKQAGSSSASQGCNNQ", "length": 384 }, "evidence": [ { "id": "A0A8V1ACK0", "url": "https://omabrowser.org/oma/group/A0A8V1ACK0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P49071-1", "protein_name": "MAP kinase-activated protein kinase 2", "gene_name": "MAPk-Ak2", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MLSLQNQRQPKTTPLTDDYVTSNTVLGYGINGKVVQCTHRRTQQNYALKVLLDSERARREVDLHWRVSGCRYIVNIIDVYENTFKDRKCLLVVMECMEGGELFQRIQDKADGAFTEREAAQIMHEICAAVDYLHSRDIAHRDLKPENLLYTTTQPNATLKLTDFGFAKETFTSYTLQTPCYTPYYVAPEVLGPEKYDKSCDIWSLGVVMYIIMCGFPPFYSNHGLAISPGMKNRIRTGQYDFPDPEWTNVSQAAKDLIKGMLNVDPSKRLRIQDVISNKWIAQYNAVPQTPLCTGRMLKEAEETWPEVQEEMTRSLATMRVDYDQMQIKALDKSNNPLLTKRRKKIEEMELYMANATRN", "length": 359 }, "evidence": [ { "id": "A0A8V1ACK0", "url": "https://omabrowser.org/oma/group/A0A8V1ACK0/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q3SYZ2-1", "protein_name": "MAP kinase-activated protein kinase 3", "gene_name": "MAPKAPK3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MDVETAEEQGGPAPPSGVPCGPCSAGAPALGGRREPKKYAVTDDYQLSKQVLGLGVNGKVLECFHRRTGQKCALKLLYDSPKARQEVDHHWQASGGPHIVRILDVYENMHHSKRCLLIIMECMEGGELFSRIQERGDQAFTEREAAEIMRDIGTAIQFLHSRNIAHRDVKPENLLYTSKDKDAVLKLTDFGFAKETTQNALQTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGFPPFYSNTGQAISPGMKRRIRLGQYGFPSPEWSEVSEDAKQLIRLLLKTDPTERLTITQFMNHPWINQSMVVPQTPLHTARVLQEDRDHWDEVKEEMTSALATMRVDYDQVKIKDLKTSNNRLLNKRRKKQAGSSSGSQGCNNQ", "length": 384 }, "evidence": [ { "id": "A0A8V1ACK0", "url": "https://omabrowser.org/oma/group/A0A8V1ACK0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q3UMW7-1", "protein_name": "MAP kinase-activated protein kinase 3", "gene_name": "Mapkapk3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDGETAGEKGSLVPPPGALGGSALGGAPAPGVRREPKKYAVTDDYQLSKQVLGLGVNGKVLECYHRRSGQKCALKLLYDSPKARQEVDHHWQASGGPHIVRILDVYENMHHGKRCLLIVMECMEGGELFSRIQERGDQAFTEREAAEIMRDIGTAIQFLHSRNIAHRDVKPENLLYTSKEKDAVLKLTDFGFAKETTQNALQTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGFPPFYSNTGQAISPGMKRRIRLGQYSFPNPEWLDVSEDAKQLIRLLLKTDPTERLTIMQFMNHPWINQSMVVPQTPLYTARVLQEDKDHWDDVKEEMTSALATMRVDYDQVKIKDLKTSNNRLLNKRRKKQAGSSSASQGCNNQ", "length": 384 }, "evidence": [ { "id": "A0A8V1ACK0", "url": "https://omabrowser.org/oma/group/A0A8V1ACK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q66H84-1", "protein_name": "MAP kinase-activated protein kinase 3", "gene_name": "Mapkapk3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDGETAGEKGSLVPQPGALGAPALGGAPAPGVRREPKKYAVTDDYQLSKQVLGLGVNGKVLECYHRRSGQKCALKLLYDSPKARQEVDHHWQASGGPHIVRILDVYENMHHGKRCLLIVMECMEGGELFSRIQERGDQAFTEREAAEIMRDIGTAIQFLHSQNIAHRDVKPENLLYTSKEKDAVLKLTDFGFAKETTQNALQTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGFPPFYSNTGQAISPGMKRRIRLGQYGFPKPEWADVSEDAKQLIRLLLKTDPTERLTIMQFMNHPWINQSMEVPQTPLHTARVLEEDKDHWDDVKEEMTSALATMRVDYDQVKIKDLKTSNNRLLNKRRKKQGGSSSASPGCNNQ", "length": 384 }, "evidence": [ { "id": "A0A8V1ACK0", "url": "https://omabrowser.org/oma/group/A0A8V1ACK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACK0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK0" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACK0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK0" } ], "pmid": "" }, { "name": "calmodulin binding", "id": "GO:0005516", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005516", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACK0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK0" } ], "pmid": "" }, { "name": "calcium/calmodulin-dependent protein kinase activity", "id": "GO:0004683", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004683", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACK0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACK0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK0" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACK0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK0" } ], "pmid": "" }, { "name": "postsynaptic density", "id": "GO:0014069", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014069", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACK0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK0" } ], "pmid": "" }, { "name": "neuron projection", "id": "GO:0043005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043005", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACK0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "response to lipopolysaccharide", "id": "GO:0032496", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032496", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACK0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK0" } ], "pmid": "" }, { "name": "MAPK cascade", "id": "GO:0000165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000165", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACK0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK0" } ], "pmid": "" }, { "name": "response to cytokine", "id": "GO:0034097", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034097", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACK0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK0" } ], "pmid": "" }, { "name": "regulation of protein localization to plasma membrane", "id": "GO:1903076", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903076", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACK0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK0" } ], "pmid": "" }, { "name": "regulation of neuronal synaptic plasticity", "id": "GO:0048168", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048168", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACK0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK0" } ], "pmid": "" }, { "name": "toll-like receptor signaling pathway", "id": "GO:0002224", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002224", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACK0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK0" } ], "pmid": "" }, { "name": "macropinocytosis", "id": "GO:0044351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACK0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 346, "end_pos": 348, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "17989", "name": "", "equation": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q6U1I9-1", "A0A8V0XNJ2-1", "A0A8V0ZUL0-1", "A0A8V0ZT63-1", "A0A8V1ACW2-1", "A0A8V0Z1X0-1", "A0A8V0YHN2-1", "A0A8V0YMN5-1", "A0A8V0Z807-1", "A0A8V0Z930-1", "A0A8V0YFR6-1", "A0A1D5P0M9-1", "A0A8V0ZBN6-1", "A0A3Q2U9U9-1", "A0A8V0YXZ5-1", "A0A8V0ZSP4-1", "A0A8V0ZXQ9-1", "A0A8V0ZZV3-1", "A0A8V1ADF0-1", "A0A8V0ZFT3-1", "A0A8V0ZA45-1", "A0A8V0ZB33-1", "A0A8V0ZD70-1", "A0A8V0Z8T4-1", "R4GIN8-1", "A0A8V0ZK64-1", "A0A8V0ZC16-1", "A0A8V0ZWW1-1", "E1BY69-1", "A0A8V0ZDW9-1", "A0A8V0ZKA2-1", "A0A3Q3B2F1-1", "F1P356-1", "A0A8V1AHA8-1", "Q8QFP8-1", "F1P011-1", "A0A8V0YKK3-1", "A0A1D5NWT4-1", "A0A1D5PMQ7-1", "E1BWA3-1", "F1NVF2-1", "A0A1D5PXN4-1", "A0A3Q2TY19-1", "A0A3Q2U592-1", "A0A8V0XCV5-1", "A0A1D5P8A9-1", "A0A1D5PMG2-1", "A0A8V0X1Q7-1", "A0A8V0Y935-1", "A0A8V0YM96-1", "A0A8V0YF83-1", "A0A8V0YJP9-1", "A0A8V1AKW4-1", "A0A8V0ZSB4-1", "F1NBT0-1", "P18652-1", "P21868-1", "P21869-1", "P53666-1", "P79996-1", "Q5F3W3-1", "Q5ZJS0-1", "Q5ZKN1-1", "Q5ZLL1-1", "A0A8V0XCS0-1", "A0A8V0XNK8-1", "A0A8V0XLV6-1", "A0A8V0XDR5-1", "E1BYH2-1", "E1BQN6-1", "A0A8V0XU71-1", "Q5ZJH6-1", "A0A8V0Y3D1-1", "A0A8V0Y7C3-1", "A0A8V0YCY4-1", "A0A8V0YIV6-1", "A0A8V0YK18-1", "A0A8V0YM22-1", "A0A8V0YTN5-1", "A0A8V0YTP2-1", "Q5F3L1-1", "A0A8V0Y3L2-1", "A0A8V0YCY8-1", "A0A8V0Y9Q1-1", "A0A8V0ZD48-1", "A0A8V0ZD60-1", "A0A8V0ZBZ2-1", "A0A8V0Z9J0-1", "A0A8V1ABF3-1", "Q8AYC9-1", "A0A8V0Z927-1", "A0A8V1A2T9-1", "Q5ZKI0-1", "Q7T0B1-1", "P10741-1", "A0A8V0YFH4-1", "E1C848-1", "A0A8V0X8M1-1", "E1BW33-1", "A0A8V0Z283-1", "A0A8V0Z157-1", "A0A3Q2U4X3-1", "A0A8V0XW11-1", "E1BUG0-1", "A0A8V1ABP4-1", "A0A8V1AJA4-1", "A0A8V1AEH4-1", "F1NJH1-1", "A0A8V1AMK5-1", "A0A3Q2TRY2-1", "A0A8V0X3D6-1", "A0A1D5PD64-1", "A0A8V0XQ97-1", "R4GJB8-1", "A0A8V0X5Z8-1", "A0A8V0XG21-1", "A0A8V0XB58-1", "A0A8V0XMX8-1", "A0A8V0XQS0-1", "A0A8V0XW29-1", "A0A8V0Y074-1", "A0A8V0XXB8-1", "A0A8V0XQ14-1", "A0A8V0XMT1-1", "A0A8V0Y457-1", "A0A8V0Y823-1", "A0A8V0Y4L8-1", "A0A8V0XND6-1", "A0A8V0YZ74-1", "A0A8V0YTI1-1", "A0A8V0YLV1-1", "A0A8V0Z2E3-1", "A0A8V0YCV9-1", "A0A8V0YSH3-1", "A0A8V0YYX2-1", "A0A8V0YZY4-1", "Q5ZIU3-1", "A0A8V0YZK0-1", "A0A8V0ZKM9-1", "A0A8V0ZWC7-1", "A0A8V1A1Y7-1", "A0A8V1A069-1", "A0A8V0ZI32-1", "A0A8V0ZH91-1", "E1BQV7-1", "A0A8V0ZRX1-1", "A0A8V0ZUU9-1", "A0A8V1A0Y8-1", "A0A8V1A7E9-1", "A0A8V1A7E0-1", "A0A8V1A3T8-1", "A0A8V1A9S5-1", "A0A8V1A7M0-1", "A0A8V1A675-1", "A0A8V1A1P3-1", "A0A8V1ADT4-1", "E1BWT0-1", "A0A8V1ACF6-1", "A0A8V1ADN9-1", "A0A8V1AM12-1", "A0A8V1A4Q4-1", "Q90891-1", "A0A1D5P517-1", "F1NB57-1", "F1NUX4-1", "A0A8V0ZZE4-1", "P05625-1", "P13863-1", "P67962-1", "Q04982-2", "Q0GGW5-1", "Q6XUX0-1", "Q8QGX4-1", "Q9I9E0-1", "Q9IA88-1", "Q5ZJK4-1", "A0A1D5PTJ8-1", "E1C2I2-1", "F1NCX7-1", "F1NKW3-1", "A0A8V1A0W4-1", "A0A8V1A4J8-1", "A0A8V1ACK0-1", "F1NCY7-1", "A0A8V0X6T4-1", "A0A8V0ZFM2-1", "A0A8V0XUM6-1", "A0A8V0XEA3-1", "A0A8V1AIY7-1", "A0A8V0YHH2-1", "A0A3Q2UI52-1", "A0A8V0ZZK5-1", "A0A8V0ZPX2-1", "A0A8V1ACB5-1", "A0A8V0YDH4-1", "A0A8V1AFS4-1", "A0A8V1AH12-1", "A0A8V0YRC9-1", "A0A8V0ZQT5-1", "A0A8V0ZFP1-1", "E1C764-1", "A0A1D5PUY5-1", "F1P4G3-1", "A0A8V0ZMK1-1", "A0A8V0Y2I5-1", "A0A8V0ZLU3-1", "A0A8V0ZNP7-1", "A0A8V0Z2Z3-1", "A0A8V0YNI5-1", "Q90771-1", "A0A8V0X4P0-1", "A0A8V0X7R2-1", "A0A3Q3A664-1", "A0A8V0YGW2-1", "E1C581-1", "A0A8V1AC40-1", "A0A3Q2TUS7-1", "A0A1D5PA08-1", "A0A8V0XFW1-1", "A0A8V0XAH9-1", "A0A8V1A4A1-1", "A0A8V0ZD40-1", "A0A8V0Z6T1-1", "A0A8V1A4V7-1", "E1C093-1", "A0A8V0YZF2-1", "E1BX69-1", "A0A8V0XI18-1", "A0A8V0Y955-1", "A0A1D5PB73-1", "A0A1D5PV76-1", "A0A1D5PX90-1", "A0A1L1RWI9-1", "A0A3Q2TV19-1", "A0A3Q2UF44-1", "A0A8V0X4Q3-1", "A0A8V0Z124-1", "A0A8V0Z6K4-1", "A0A8V1AE45-1", "A0A8V0YZV9-1", "A0A8V0YYZ3-1", "A0A8V0ZUC6-1", "A0A8V0ZUU8-1", "A0A8V1AG70-1", "F1NA68-1", "F1NLR7-1", "A0A8V0Y6K1-1", "A0A8V0XS42-1", "A0A8V0YRN4-1", "A0A8V0YFP8-1", "A0A8V1A7P9-1", "A0A1D5PRN8-1", "A0A3Q3AAD7-1", "A0A3Q2TWZ8-1", "A0A8V0XBZ0-1", "A0A8V0XFX2-1", "A0A8V0YFL1-1", "A0A8V0YTL9-1", "A0A8V0YMB3-1", "A0A8V0X2Y2-1", "A0A8V0XCY6-1", "A0A3Q2UI62-1", "A0A8V0Y241-1", "A0A8V0Z8G2-1", "A0A8V1ABR8-1", "A0A8V1AP60-1", "A0A8V0YZM1-1", "A0A8V0ZB38-1", "A0A8V0Z466-1", "A0A8V0ZA06-1", "A0A8V1AMQ2-1", "A0A8V0ZGY3-1", "A0A8V0ZQJ2-1", "A0A8V0ZYU6-1", "A0A8V1A513-1", "A0A8V0XE48-1", "A0A8V0XQQ4-1", "A0A8V0XKG0-1" ], "evidence": [ { "id": "17989", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/17989" } ] }, { "id": "46608", "name": "", "equation": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A1D5PUY5-1", "Q6U1I9-1", "A0A8V0XNJ2-1", "A0A8V0ZUL0-1", "A0A8V0ZT63-1", "A0A8V1ACW2-1", "A0A8V0Z1X0-1", "A0A8V0YHN2-1", "A0A8V0YMN5-1", "A0A8V0Z807-1", "A0A8V0Z930-1", "A0A8V0YFR6-1", "A0A1D5P0M9-1", "A0A8V0ZBN6-1", "A0A3Q2U9U9-1", "A0A8V0YRC9-1", "A0A8V0YXZ5-1", "A0A8V0ZSP4-1", "A0A8V0ZXQ9-1", "A0A8V0ZZV3-1", "A0A8V1ADF0-1", "A0A8V0ZFT3-1", "A0A8V0ZA45-1", "A0A8V0ZB33-1", "A0A8V0ZD70-1", 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"A0A8V1A7E0-1", "A0A8V1A3T8-1", "A0A8V1A9S5-1", "A0A8V1A7M0-1", "A0A8V1A675-1", "A0A8V1A1P3-1", "A0A8V1ADT4-1", "E1BWT0-1", "A0A8V1ACF6-1", "A0A8V1ADN9-1", "A0A8V1AM12-1", "A0A8V1A4Q4-1", "Q90891-1", "F1NUX4-1", "A0A8V0ZZE4-1", "P05625-1", "P13863-1", "Q04982-2", "Q0GGW5-1", "Q6XUX0-1", "Q8QGX4-1", "Q9I9E0-1", "Q9IA88-1", "Q5ZJK4-1", "A0A1D5PTJ8-1", "E1C2I2-1", "F1NCX7-1", "F1NKW3-1", "A0A8V1A0W4-1", "A0A8V1A4J8-1", "A0A8V1ACK0-1", "F1NCY7-1", "A0A8V0X6T4-1", "A0A8V0XUM6-1", "A0A8V0XEA3-1", "A0A8V0YHH2-1", "A0A3Q2UI52-1", "A0A8V0ZZK5-1", "A0A8V0ZPX2-1", "A0A8V1ACB5-1", "A0A8V0YDH4-1", "A0A8V1AFS4-1", "A0A8V1AH12-1", "A0A8V0ZQT5-1", "A0A8V0ZFP1-1", "E1C764-1", "F1P4G3-1", "A0A8V0Y2I5-1", "A0A8V0ZLU3-1", "A0A8V0ZNP7-1", "A0A8V0Z2Z3-1", "A0A8V0YNI5-1", "Q90771-1", "A0A8V0X4P0-1", "A0A8V0X7R2-1", "A0A3Q3A664-1", "A0A8V0YGW2-1", "E1C581-1", "A0A8V1AC40-1", "A0A3Q2TUS7-1", "A0A1D5PA08-1", "A0A8V0XFW1-1", "A0A8V0XAH9-1", "A0A8V0ZFM2-1", "A0A8V1A4A1-1", "A0A8V0ZD40-1", "A0A8V0Z6T1-1", "A0A8V1A4V7-1", "A0A8V0YZF2-1", "E1BX69-1", "A0A8V0Y955-1", "A0A1D5PB73-1", "A0A1D5PV76-1", "A0A1D5PX90-1", "A0A1L1RWI9-1", "A0A3Q2TV19-1", "A0A3Q2UF44-1", "A0A8V0X4Q3-1", "A0A8V0Z124-1", "A0A8V0Z6K4-1", "A0A8V1AIY7-1", "A0A8V1AE45-1", "A0A8V0YZV9-1", "A0A8V0YYZ3-1", "A0A8V0ZUC6-1", "A0A8V0ZUU8-1", "A0A8V1AG70-1", "F1NA68-1", "F1NLR7-1", "A0A8V0Y6K1-1", "A0A8V0XS42-1", "A0A8V0YRN4-1", "A0A8V0YFP8-1", "A0A8V1A7P9-1", "A0A1D5PRN8-1", "A0A3Q3AAD7-1", "A0A3Q2TWZ8-1", "A0A8V0XBZ0-1", "A0A8V0XFX2-1", "A0A8V0YFL1-1", "A0A8V0YTL9-1", "A0A8V0YMB3-1", "A0A8V0X2Y2-1", "A0A8V0XCY6-1", "A0A3Q2UI62-1", "A0A8V0Y241-1", "A0A8V0Z8G2-1", "A0A8V1ABR8-1", "A0A8V1AP60-1", "A0A8V0YZM1-1", "A0A8V0ZB38-1", "A0A8V0Z466-1", "A0A8V0ZA06-1", "A0A8V1AMQ2-1", "A0A8V0ZGY3-1", "A0A8V0ZQJ2-1", "A0A8V0ZYU6-1", "A0A8V1A513-1", "A0A8V0XE48-1", "A0A8V0XKG0-1" ], "evidence": [ { "id": "46608", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/46608" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5NWT4", "gene_name": "RPS6KA3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5NWT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NWT4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5NWT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NWT4" } ] } ] }, { "uniprot_ac": "A0A1D5P0M9", "gene_name": "MAP3K13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5P0M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P0M9" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A1D5P0M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P0M9" } ] } ] }, { "uniprot_ac": "A0A1D5P517", "gene_name": "PLK3", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5P517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P517" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A1D5P517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P517" } ] } ] }, { "uniprot_ac": "A0A1D5P8A9", "gene_name": "SNRK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5P8A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P8A9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5P8A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P8A9" } ] } ] }, { "uniprot_ac": "A0A1D5PA08", "gene_name": "STK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP 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"id": "A0A1D5PD64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PD64" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A1D5PD64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PD64" } ] } ] }, { "uniprot_ac": "A0A1D5PMG2", "gene_name": "DCLK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PMG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMG2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5PMG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMG2" } ] } ] }, { "uniprot_ac": "A0A1D5PMQ7", "gene_name": "STK40", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PMQ7", "database": "UniProtKB", "url": 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"https://www.uniprot.org/uniprotkb/A0A8V0XDR5" } ] } ] }, { "uniprot_ac": "A0A8V0XE48", "gene_name": "ROCK2", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XE48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XE48" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "A0A8V0XE48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XE48" } ] } ] }, { "uniprot_ac": "A0A8V0XEA3", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XEA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEA3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XEA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEA3" } ] } ] }, { "uniprot_ac": "A0A8V0XFW1", "gene_name": "SGK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XFW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFW1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XFW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFW1" } ] } ] }, { "uniprot_ac": "A0A8V0XFX2", "gene_name": "NEK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XFX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFX2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XFX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFX2" } ] } ] }, { "uniprot_ac": "A0A8V0XG21", "gene_name": "LOC107050335", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XG21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XG21" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XG21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XG21" } ] } ] }, { "uniprot_ac": "A0A8V0XI18", "gene_name": "ATM", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XI18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XI18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XI18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XI18" } ] } ] }, { "uniprot_ac": "A0A8V0XKG0", "gene_name": "NEK9", "activity": [ { "ec_number": "2.7.11.38", "activity": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XKG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XKG0" } ] }, { "ec_number": "2.7.11.38", "activity": "", "evidence": [ { "id": "A0A8V0XKG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XKG0" } ] } ] }, { "uniprot_ac": "A0A8V0XLV6", "gene_name": "MAPK10", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XLV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLV6" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0XLV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLV6" } ] } ] }, { "uniprot_ac": "A0A8V0XMT1", "gene_name": "MOS", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XMT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMT1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XMT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMT1" } ] } ] }, { "uniprot_ac": "A0A8V0XMX8", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMX8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMX8" } ] } ] }, { "uniprot_ac": "A0A8V0XND6", "gene_name": "RIOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XND6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XND6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XND6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XND6" } ] } ] }, { "uniprot_ac": "A0A8V0XNJ2", "gene_name": "CDK8", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] } ] }, { "uniprot_ac": "A0A8V0XNK8", "gene_name": "PRKCQ", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XNK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNK8" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0XNK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNK8" } ] } ] }, { "uniprot_ac": "A0A8V0XQ14", "gene_name": "PLK4", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQ14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ14" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A8V0XQ14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ14" } ] } ] }, { "uniprot_ac": "A0A8V0XQ97", "gene_name": "CDK14", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQ97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ97" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0XQ97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ97" } ] } ] }, { "uniprot_ac": "A0A8V0XQQ4", "gene_name": "NME7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQQ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQQ4" } ] } ] }, { "uniprot_ac": "A0A8V0XQS0", "gene_name": "STK24", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQS0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XQS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQS0" } ] } ] }, { "uniprot_ac": "A0A8V0XS42", "gene_name": "MAP3K4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XS42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XS42" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0XS42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XS42" } ] } ] }, { "uniprot_ac": "A0A8V0XU71", "gene_name": "MYO3A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XU71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU71" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XU71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU71" } ] } ] }, { "uniprot_ac": "A0A8V0XU96", "gene_name": "PRKD1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XU96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU96" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0XU96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU96" } ] } ] }, { "uniprot_ac": "A0A8V0XUM6", "gene_name": "LATS1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XUM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XUM6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XUM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XUM6" } ] } ] }, { "uniprot_ac": "A0A8V0XW11", "gene_name": "RPS6KA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XW11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW11" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XW11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW11" } ] } ] }, { "uniprot_ac": "A0A8V0XW29", "gene_name": "CDKL2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XW29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW29" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0XW29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW29" } ] } ] }, { "uniprot_ac": "A0A8V0XXB8", "gene_name": "MAPK15", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XXB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXB8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0XXB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXB8" } ] } ] }, { "uniprot_ac": "A0A8V0Y074", "gene_name": "NEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y074", "database": "UniProtKB", "url": 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"ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] } ] }, { "uniprot_ac": "A0A8V0Y3D1", "gene_name": "LRRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y3D1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3D1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y3D1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3D1" } ] } ] }, { "uniprot_ac": "A0A8V0Y3L2", "gene_name": "MLK4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y3L2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3L2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0Y3L2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3L2" } ] } ] }, { "uniprot_ac": "A0A8V0Y457", "gene_name": "PRPF4B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y457", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y457" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y457", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y457" } ] } ] }, { "uniprot_ac": "A0A8V0Y4L8", "gene_name": "HUNK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y4L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y4L8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y4L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y4L8" } ] } ] }, { "uniprot_ac": "A0A8V0Y6K1", "gene_name": "MAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6K1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6K1" } ] } ] }, { "uniprot_ac": "A0A8V0Y7C3", "gene_name": "DAPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y7C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7C3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y7C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7C3" } ] } ] }, { "uniprot_ac": "A0A8V0Y823", "gene_name": "SRPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y823", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y823" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y823", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y823" } ] } ] }, { "uniprot_ac": "A0A8V0Y8X9", "gene_name": "PRKACA", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y8X9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8X9" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0A8V0Y8X9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8X9" } ] } ] }, { "uniprot_ac": "A0A8V0Y935", "gene_name": "MAST4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y935", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y935" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y935", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y935" } ] } ] }, { "uniprot_ac": "A0A8V0Y955", "gene_name": "PAK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y955", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y955" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y955", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y955" } ] } ] }, { "uniprot_ac": "A0A8V0Y9Q1", "gene_name": "LOC107055388", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y9Q1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9Q1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y9Q1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9Q1" } ] } ] }, { "uniprot_ac": "A0A8V0YCV9", "gene_name": "SIK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YCV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YCV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCV9" } ] } ] }, { "uniprot_ac": "A0A8V0YCY4", "gene_name": "AURKB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YCY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YCY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY4" } ] } ] }, { "uniprot_ac": "A0A8V0YCY8", "gene_name": "RIOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YCY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YCY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY8" } ] } ] }, { "uniprot_ac": "A0A8V0YDH4", "gene_name": "ALPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YDH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDH4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YDH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDH4" } ] } ] }, { "uniprot_ac": "A0A8V0YF83", "gene_name": "WNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YF83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF83" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YF83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF83" } ] } ] }, { "uniprot_ac": "A0A8V0YFH4", "gene_name": "NRK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFH4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YFH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFH4" } ] } ] }, { "uniprot_ac": "A0A8V0YFL1", "gene_name": "CDK19", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0YFL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL1" } ] } ] }, { "uniprot_ac": "A0A8V0YFP8", "gene_name": "RIPK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFP8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YFP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFP8" } ] } ] }, { "uniprot_ac": "A0A8V0YFR6", "gene_name": "TNIK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFR6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YFR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFR6" } ] } ] }, { "uniprot_ac": "A0A8V0YGW2", "gene_name": "STK32B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YGW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGW2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YGW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGW2" } ] } ] }, { "uniprot_ac": "A0A8V0YHH2", "gene_name": "STK38L", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YHH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHH2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YHH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHH2" } ] } ] }, { "uniprot_ac": "A0A8V0YHN2", "gene_name": "RPS6KA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YHN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YHN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN2" } ] } ] }, { "uniprot_ac": "A0A8V0YIV6", "gene_name": "DYRK1A", "activity": [ { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] } ] }, { "uniprot_ac": "A0A8V0YJP9", "gene_name": "RIOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YJP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YJP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP9" } ] } ] }, { "uniprot_ac": "A0A8V0YK18", "gene_name": "CDC42BPB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YK18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YK18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK18" } ] } ] }, { "uniprot_ac": "A0A8V0YKK3", "gene_name": "MAP4K4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKK3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKK3" } ] } ] }, { "uniprot_ac": "A0A8V0YLV1", "gene_name": "MARK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YLV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLV1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YLV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLV1" } ] } ] }, { "uniprot_ac": "A0A8V0YM22", "gene_name": "MYO3AL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YM22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM22" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YM22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM22" } ] } ] }, { "uniprot_ac": "A0A8V0YM96", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YM96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM96" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YM96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM96" } ] } ] }, { "uniprot_ac": "A0A8V0YMB3", "gene_name": "STK32A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMB3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMB3" } ] } ] }, { "uniprot_ac": "A0A8V0YMN5", "gene_name": "BRAF", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YMN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YMN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN5" } ] } ] }, { "uniprot_ac": "A0A8V0YNI5", "gene_name": "NIM1K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YNI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNI5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YNI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNI5" } ] } ] }, { "uniprot_ac": "A0A8V0YRC9", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] } ] }, { "uniprot_ac": "A0A8V0YRN4", "gene_name": "GAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRN4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YRN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRN4" } ] } ] }, { "uniprot_ac": "A0A8V0YSH3", "gene_name": "RPS6KA6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YSH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSH3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YSH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSH3" } ] } ] }, { "uniprot_ac": "A0A8V0YTI1", "gene_name": "TSSK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTI1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTI1" } ] } ] }, { "uniprot_ac": "A0A8V0YTL9", "gene_name": "VRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTL9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTL9" } ] } ] }, { "uniprot_ac": "A0A8V0YTN5", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTN5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTN5" } ] } ] }, { "uniprot_ac": "A0A8V0YTP2", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTP2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTP2" } ] } ] }, { "uniprot_ac": "A0A8V0YXZ5", "gene_name": "CDC42BPA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YXZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXZ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YXZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXZ5" } ] } ] }, { "uniprot_ac": "A0A8V0YYX2", "gene_name": "PAK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YYX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYX2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YYX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYX2" } ] } ] }, { "uniprot_ac": "A0A8V0YYZ3", "gene_name": "SPEG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YYZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYZ3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YYZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYZ3" } ] } ] }, { "uniprot_ac": "A0A8V0YZ74", "gene_name": "MAP2K5", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZ74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZ74" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V0YZ74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZ74" } ] } ] }, { "uniprot_ac": "A0A8V0YZF2", "gene_name": "PAK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZF2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YZF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZF2" } ] } ] }, { "uniprot_ac": "A0A8V0YZK0", "gene_name": "MAP3K6", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZK0" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0YZK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZK0" } ] } ] }, { "uniprot_ac": "A0A8V0YZM1", "gene_name": "MOK", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] }, { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] } ] }, { "uniprot_ac": "A0A8V0YZV9", "gene_name": "ATR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YZV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZV9" } ] } ] }, { "uniprot_ac": "A0A8V0YZY4", "gene_name": "SBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZY4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YZY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZY4" } ] } ] }, { "uniprot_ac": "A0A8V0Z124", "gene_name": "VRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z124", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z124" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z124", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z124" } ] } ] }, { "uniprot_ac": "A0A8V0Z157", "gene_name": "MARK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] } ] }, { "uniprot_ac": "A0A8V0Z1X0", "gene_name": "MAP4K3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z1X0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1X0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z1X0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1X0" } ] } ] }, { "uniprot_ac": "A0A8V0Z283", "gene_name": "MARK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] } ] }, { "uniprot_ac": "A0A8V0Z2E3", "gene_name": "PDIK1L", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z2E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2E3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z2E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2E3" } ] } ] }, { "uniprot_ac": "A0A8V0Z2Z3", "gene_name": "AAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z2Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2Z3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z2Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2Z3" } ] } ] }, { "uniprot_ac": "A0A8V0Z466", "gene_name": "MAP3K19", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z466", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z466" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z466", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z466" } ] } ] }, { "uniprot_ac": "A0A8V0Z6K4", "gene_name": "PIK3R4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z6K4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6K4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z6K4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6K4" } ] } ] }, { "uniprot_ac": "A0A8V0Z6T1", "gene_name": "ERN2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z6T1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6T1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z6T1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6T1" } ] } ] }, { "uniprot_ac": "A0A8V0Z807", "gene_name": "NEK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z807", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z807" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z807", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z807" } ] } ] }, { "uniprot_ac": "A0A8V0Z8G2", "gene_name": "TTBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": 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"ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z9J0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9J0" } ] } ] }, { "uniprot_ac": "A0A8V0ZA06", "gene_name": "CDKL1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA06" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0ZA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA06" } ] } ] }, { "uniprot_ac": "A0A8V0ZA45", "gene_name": "MAP4K5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZA45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA45" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZA45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA45" } ] } ] }, { "uniprot_ac": "A0A8V0ZB33", "gene_name": "CAMK2G", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZB33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB33" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V0ZB33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB33" } ] } ] }, { "uniprot_ac": "A0A8V0ZB38", "gene_name": "CIITA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZB38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB38" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZB38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB38" } ] } ] }, { "uniprot_ac": "A0A8V0ZBN6", "gene_name": "MAP2K1", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZBN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBN6" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V0ZBN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBN6" } ] } ] }, { "uniprot_ac": "A0A8V0ZBZ2", "gene_name": "MAP3K9", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZBZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBZ2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0ZBZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBZ2" } ] } ] }, { "uniprot_ac": "A0A8V0ZC16", "gene_name": "KALRN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZC16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC16" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZC16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC16" } ] } ] }, { "uniprot_ac": "A0A8V0ZD40", "gene_name": "CDC2L1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] } ] }, { "uniprot_ac": "A0A8V0ZD48", "gene_name": "PRKCE", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD48" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0ZD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD48" } ] } ] }, { "uniprot_ac": "A0A8V0ZD60", "gene_name": "STK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZD60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD60" } ] } ] }, { "uniprot_ac": "A0A8V0ZD70", "gene_name": "DCLK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD70" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZD70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD70" } ] } ] }, { "uniprot_ac": "A0A8V0ZDW9", "gene_name": "NEK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": 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"ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZGY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGY3" } ] } ] }, { "uniprot_ac": "A0A8V0ZH91", "gene_name": "WNK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZH91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH91" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZH91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH91" } ] } ] }, { "uniprot_ac": "A0A8V0ZI32", "gene_name": "STK16", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZI32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI32" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": 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H(+).", "evidence": [ { "id": "A0A8V0ZRX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRX1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZRX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRX1" } ] }, { "ec_number": "2.1.1.-", "activity": "", "evidence": [ { "id": "A0A8V0ZRX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRX1" } ] } ] }, { "uniprot_ac": "A0A8V0ZSB4", "gene_name": "SIK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZSB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSB4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZSB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSB4" } ] } ] }, { "uniprot_ac": "A0A8V0ZSP4", "gene_name": "PKN2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] }, { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] } ] }, { "uniprot_ac": "A0A8V0ZT63", "gene_name": "STK25", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZT63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT63" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZT63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT63" } ] } ] }, { "uniprot_ac": "A0A8V0ZUC6", "gene_name": "PAK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUC6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUC6" } ] } ] }, { "uniprot_ac": "A0A8V0ZUL0", "gene_name": "PASK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUL0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUL0" } ] } ] }, { "uniprot_ac": "A0A8V0ZUU8", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU8" } ] } ] }, { "uniprot_ac": "A0A8V0ZUU9", "gene_name": "MKNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU9" } ] } ] }, { "uniprot_ac": "A0A8V0ZWC7", "gene_name": "EIF2AK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZWC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWC7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZWC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWC7" } ] } ] }, { "uniprot_ac": "A0A8V0ZWW1", "gene_name": "MAP3K12", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZWW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWW1" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0ZWW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWW1" } ] } ] }, { "uniprot_ac": "A0A8V0ZXQ9", "gene_name": "PRKG1", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZXQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXQ9" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0A8V0ZXQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXQ9" } ] } ] }, { "uniprot_ac": "A0A8V0ZYU6", "gene_name": "TNNI3K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZYU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYU6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZYU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYU6" } ] } ] }, { "uniprot_ac": "A0A8V0ZZE4", "gene_name": "OBSCN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZZE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZE4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZZE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZE4" } ] } ] }, { "uniprot_ac": "A0A8V0ZZK5", "gene_name": "STK38", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZZK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZK5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZZK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZK5" } ] } ] }, { 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{ "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A0W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0W4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A0W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0W4" } ] } ] }, { "uniprot_ac": "A0A8V1A0Y8", "gene_name": "MAST2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A0Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Y8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A0Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Y8" } ] } ] }, { "uniprot_ac": "A0A8V1A1P3", "gene_name": "SRPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A1P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1P3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A1P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1P3" } ] } ] }, { "uniprot_ac": "A0A8V1A1Y7", "gene_name": "CDK2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A1Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1Y7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V1A1Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1Y7" } ] } ] }, { "uniprot_ac": "A0A8V1A2T9", "gene_name": "MAP3K14", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A2T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2T9" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V1A2T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2T9" } ] } ] }, { "uniprot_ac": "A0A8V1A3T8", "gene_name": "MAST3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A3T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3T8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A3T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3T8" } ] } ] }, { "uniprot_ac": "A0A8V1A4A1", "gene_name": "CAMKK2", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4A1", "database": "UniProtKB", "url": 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"ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1A4Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Q4" } ] } ] }, { "uniprot_ac": "A0A8V1A4V7", "gene_name": "HIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A4V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V7" } ] } ] }, { "uniprot_ac": "A0A8V1A513", "gene_name": "DAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A513" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A513" } ] } ] }, { "uniprot_ac": "A0A8V1A675", "gene_name": "CSNK1G2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A675", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A675" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A675", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A675" } ] } ] }, { "uniprot_ac": "A0A8V1A7E0", "gene_name": "DYRK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1A7E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E0" } ] } ] }, { "uniprot_ac": "A0A8V1A7E9", "gene_name": "SIK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E9" } ] } ] }, { "uniprot_ac": "A0A8V1A7M0", "gene_name": "STK39", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M0" } ] } ] }, { "uniprot_ac": "A0A8V1A7P9", "gene_name": "DCAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] } ] }, { "uniprot_ac": "A0A8V1A9S5", "gene_name": "NUAK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A9S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9S5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A9S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9S5" } ] } ] }, { "uniprot_ac": "A0A8V1ABF3", "gene_name": "PRKAA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] } ] }, { "uniprot_ac": "A0A8V1ABP4", "gene_name": "DSTYK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP4" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1ABP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP4" } ] } ] }, { "uniprot_ac": "A0A8V1ABR8", "gene_name": "CAMK4L", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR8" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1ABR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR8" } ] } ] }, { "uniprot_ac": "A0A8V1AC40", "gene_name": "CDK18", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AC40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC40" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V1AC40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC40" } ] } ] }, { "uniprot_ac": "A0A8V1ACB5", "gene_name": "MAPK13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACB5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1ACB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACB5" } ] } ] }, { "uniprot_ac": "A0A8V1ACF6", "gene_name": "PIM1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF6" } ] } ] }, { "uniprot_ac": "A0A8V1ACK0", "gene_name": "MAPKAPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK0" } ] } ] }, { "uniprot_ac": "A0A8V1ACW2", "gene_name": "WNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACW2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACW2" } ] } ] }, { "uniprot_ac": "A0A8V1ADF0", "gene_name": "MAP2K2", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF0" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V1ADF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF0" } ] } ] }, { "uniprot_ac": "A0A8V1ADN9", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADN9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1ADN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADN9" } ] } ] }, { "uniprot_ac": "A0A8V1ADT4", "gene_name": "MKNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADT4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ADT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADT4" } ] } ] }, { "uniprot_ac": "A0A8V1AE45", "gene_name": "ERN1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AE45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE45" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AE45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE45" } ] } ] }, { "uniprot_ac": "A0A8V1AEH4", "gene_name": "STK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEH4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEH4" } ] } ] }, { "uniprot_ac": "A0A8V1AFS4", "gene_name": "STKLD1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AFS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFS4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AFS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFS4" } ] } ] }, { "uniprot_ac": "A0A8V1AG70", "gene_name": "LOC100857512", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AG70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG70" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AG70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG70" } ] } ] }, { "uniprot_ac": "A0A8V1AH12", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AH12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH12" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AH12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH12" } ] } ] }, { "uniprot_ac": "A0A8V1AHA8", "gene_name": "NEK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AHA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHA8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AHA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHA8" } ] } ] }, { "uniprot_ac": "A0A8V1AIY7", "gene_name": "AATK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AIY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AIY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIY7" } ] } ] }, { "uniprot_ac": "A0A8V1AJA4", "gene_name": "RPS6KB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AJA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJA4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AJA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJA4" } ] } ] }, { "uniprot_ac": "A0A8V1AKW4", "gene_name": "MAP2K4", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AKW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKW4" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V1AKW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKW4" } ] } ] }, { "uniprot_ac": "A0A8V1AM12", "gene_name": "GSG2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AM12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM12" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AM12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM12" } ] } ] }, { "uniprot_ac": "A0A8V1AMK5", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AMK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V1AMK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK5" } ] } ] }, { "uniprot_ac": "A0A8V1AMQ2", "gene_name": "CAMKK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AMQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ2" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1AMQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ2" } ] } ] }, { "uniprot_ac": "A0A8V1AP60", "gene_name": "KSR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AP60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AP60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP60" } ] } ] }, { "uniprot_ac": "E1BQN6", "gene_name": "PRKCZ", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQN6" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1BQN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQN6" } ] } ] }, { "uniprot_ac": "E1BQV7", "gene_name": "SLK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQV7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BQV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQV7" } ] } ] }, { "uniprot_ac": "E1BUG0", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] } ] }, { "uniprot_ac": "E1BW33", "gene_name": "SMG1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BW33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BW33" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BW33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BW33" } ] } ] }, { "uniprot_ac": "E1BWA3", "gene_name": "PRKCI", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BWA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWA3" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1BWA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWA3" } ] } ] }, { "uniprot_ac": "E1BWT0", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BWT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWT0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BWT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWT0" } ] } ] }, { "uniprot_ac": "E1BX69", "gene_name": "EIF2AK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BX69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BX69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BX69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BX69" } ] } ] }, { "uniprot_ac": "E1BY69", "gene_name": "PIM3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BY69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BY69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY69" } ] } ] }, { "uniprot_ac": "E1BYH2", "gene_name": "TAOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BYH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYH2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BYH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYH2" } ] } ] }, { "uniprot_ac": "E1C093", "gene_name": "PIK3CG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] } ] }, { "uniprot_ac": "E1C2I2", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C2I2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2I2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C2I2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2I2" } ] } ] }, { "uniprot_ac": "E1C581", "gene_name": "TBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C581", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C581" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C581", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C581" } ] } ] }, { "uniprot_ac": "E1C6T4", "gene_name": "PRKD3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C6T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C6T4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1C6T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C6T4" } ] } ] }, { "uniprot_ac": "E1C764", "gene_name": "BMP2K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C764", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C764" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C764", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C764" } ] } ] }, { "uniprot_ac": "E1C848", "gene_name": "MAP3K8", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C848", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C848" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1C848", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C848" } ] } ] }, { "uniprot_ac": "F1NA68", "gene_name": "CDK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NA68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NA68" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1NA68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NA68" } ] } ] }, { "uniprot_ac": "F1NB57", "gene_name": "PLK2", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NB57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NB57" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "F1NB57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NB57" } ] } ] }, { "uniprot_ac": "F1NBT0", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NBT0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NBT0" } ] } ] }, { "uniprot_ac": "F1NCX7", "gene_name": "PLK1", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NCX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCX7" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "F1NCX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCX7" } ] } ] }, { "uniprot_ac": "F1NCY7", "gene_name": "MAPKAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NCY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NCY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCY7" } ] } ] }, { "uniprot_ac": "F1NJH1", "gene_name": "PRKCH", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NJH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJH1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1NJH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJH1" } ] } ] }, { "uniprot_ac": "F1NKW3", "gene_name": "MAP3K15", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NKW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NKW3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1NKW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NKW3" } ] } ] }, { "uniprot_ac": "F1NLR7", "gene_name": "CLK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NLR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLR7" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "F1NLR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLR7" } ] } ] }, { "uniprot_ac": "F1NUX4", "gene_name": "MTOR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NUX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NUX4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NUX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NUX4" } ] } ] }, { "uniprot_ac": "F1NVF2", "gene_name": "MAP2K6", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NVF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVF2" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "F1NVF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVF2" } ] } ] }, { "uniprot_ac": "F1P011", "gene_name": "CAMK2A", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1P011", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P011" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F1P011", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P011" } ] } ] }, { "uniprot_ac": "F1P356", "gene_name": "NUAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1P356", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P356" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1P356", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P356" } ] } ] }, { "uniprot_ac": "F1P4G3", "gene_name": "HIPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1P4G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P4G3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1P4G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P4G3" } ] } ] }, { "uniprot_ac": "P05625", "gene_name": "RAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05625", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05625" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P05625", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05625" } ] } ] }, { "uniprot_ac": "P10741", "gene_name": "MOS", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P10741", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P10741" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P10741", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P10741" } ] } ] }, { "uniprot_ac": "P13863", "gene_name": "CDK1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13863" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13863" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13863" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13863" } ] } ] }, { "uniprot_ac": "P18652", "gene_name": "RPS6KA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P18652", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18652" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P18652", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18652" } ] } ] }, { "uniprot_ac": "P21868", "gene_name": "CSNK2A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P21868", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21868" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P21868", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21868" } ] } ] }, { "uniprot_ac": "P21869", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": 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"evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEM0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEM0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "OTOP3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEM0", "locus": { "chromosome": "18", "start_pos": 11201444, "end_pos": 11194314, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029680", "url": "https://www.ensembl.org/id/ENSGALG00010029680" } ] } } ], "crossref": [ { "id": "A0A8V1AEM0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AEM0", "database": "AlphaFoldDB", "categories": [] }, { "id": "422112", "url": "https://www.ncbi.nlm.nih.gov/gene/422112", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004878", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004878", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:422112", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422112", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NRVDMGA", "url": "https://omabrowser.org/oma/group/NRVDMGA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AEM0", "url": "https://www.orthodb.org/?gene=A0A8V1AEM0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1APS5", "url": "https://www.orthodb.org/?gene=A0A8V1APS5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21522", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21522", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21522:SF36", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21522:SF36", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03189", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03189", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1AEM0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEM0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AEM0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEM0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1APS5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APS5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1APS5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APS5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAGNKASKQKFCHHCNSRSASAPPGTSTIHYEKSWLYRHCSLQQRDRQAQKSGQLFSGLLALNVVFLGSAFISSMIFNHVAITLADVWILLSILKVLCLCWIIYYLLGTSRQPHAVLYRDTHAGPVWIRGSLLLFGTFSILLNVFQIGYSVIQINCKSKVEIVFPSIEILFVATQAFFLWHHSKDCIQVQHNLTRCGLMLTIATNLLLWLLAVTNDSIHMEIESQLQDKQLLRILRLLHYRMLTDSCACPNTTTCKVFQKGYILLYPFNTEYCLICCSVLYVMWKNVGRRISHHHITHIKPKFKLQGVVFGPLLGAAAVIIGICVFMMYQIQATGSAPNYQVFVLYYSYYIVLLPLMCVVAIIGTIIHTLEKRELDTLKNPTRSLDVVLLMGAALGQIAMSYFSIVAIVATNPRDMLNSLILSYSVLLIFQYITQNIFIIDGLQRQPFAAAEAQHTTHAGQLSAVPELPGEGVTTPSSNQERSQTFPSKEEEVSEEHNREAPDQRRVSVLELGQEFRRVSLSYIHTYSHLGWKRKALKEISFFLVLCNIILWIMPTFGAHPVFENGLQKSFYGYSTWFAIVNFGLPLSVFYRMHSVGGLLEVYVSA", "length": 606, "header": "tr|A0A8V1AEM0-1|A0A8V1AEM0_CHICK Isoform 1 of Otopetrin 3 OS=Gallus gallus OX=9031 GN=OTOP3 PE=3 SV=1 CANONICAL=A0A8V1AEM0-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AEM0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEM0/entry#A0A8V1AEM0-1", "sequence": { "sequence": "MAGNKASKQKFCHHCNSRSASAPPGTSTIHYEKSWLYRHCSLQQRDRQAQKSGQLFSGLLALNVVFLGSAFISSMIFNHVAITLADVWILLSILKVLCLCWIIYYLLGTSRQPHAVLYRDTHAGPVWIRGSLLLFGTFSILLNVFQIGYSVIQINCKSKVEIVFPSIEILFVATQAFFLWHHSKDCIQVQHNLTRCGLMLTIATNLLLWLLAVTNDSIHMEIESQLQDKQLLRILRLLHYRMLTDSCACPNTTTCKVFQKGYILLYPFNTEYCLICCSVLYVMWKNVGRRISHHHITHIKPKFKLQGVVFGPLLGAAAVIIGICVFMMYQIQATGSAPNYQVFVLYYSYYIVLLPLMCVVAIIGTIIHTLEKRELDTLKNPTRSLDVVLLMGAALGQIAMSYFSIVAIVATNPRDMLNSLILSYSVLLIFQYITQNIFIIDGLQRQPFAAAEAQHTTHAGQLSAVPELPGEGVTTPSSNQERSQTFPSKEEEVSEEHNREAPDQRRVSVLELGQEFRRVSLSYIHTYSHLGWKRKALKEISFFLVLCNIILWIMPTFGAHPVFENGLQKSFYGYSTWFAIVNFGLPLSVFYRMHSVGGLLEVYVSA", "length": 606, "header": "tr|A0A8V1AEM0-1|A0A8V1AEM0_CHICK Isoform 1 of Otopetrin 3 OS=Gallus gallus OX=9031 GN=OTOP3 PE=3 SV=1 CANONICAL=A0A8V1AEM0-1" }, "locus": { "chromosome": "18", "start_pos": 11200296, "end_pos": 11195622, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071786.1", "url": "https://www.ensembl.org/id/ENSGALT00010071786.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044476.1", "url": "https://www.ensembl.org/id/ENSGALP00010044476.1" } ] } }, { "isoform_ac": "A0A8V1APS5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEM0/entry#A0A8V1APS5-1", "sequence": { "sequence": "MAGNKASKQKFCHHCNSRSASAPPGTSTIHYEKSWLYRHCSLQQRDRQAQKSGQLFSGLLALNVVFLGSAFISSMIFNHVAITLADVWILLSILKVLCLCWIIYYLLGTSRQPHAVLYRDTHAGPVWIRGSLLLFGTFSILLNVFQIGYSVIQINCKSKVEIVFPSIEILFVATQAFFLWHHSKDCIQVQHNLTRCGLMLTIATNLLLWLLAVTNDSIHMEIESQLREVEQRLAGNETDSCACPNTTTCKVFQKGYILLYPFNTEYCLICCSVLYVMWKNVGRRISHHHITHIKPKFKLQGVVFGPLLGAAAVIIGICVFMMYQIQATGSAPNYQVFVLYYSYYIVLLPLMCVVAIIGTIIHTLEKRELDTLKNPTRSLDVVLLMGAALGQIAMSYFSIVAIVATNPRDMLNSLILSYSVLLIFQYITQNIFIIDGLQRQPFAAAEAQHTTHAGQLSAVPELPGEGVTTPSSNQERSQTFPSKEEEVSEEHNREAPDQRRVSVLELGQEFRRVSLSYIHTYSHLGWKRKALKEISFFLVLCNIILWIMPTFGAHPVFENGLQKSFYGYSTWFAIVNFGLPLSVFYRMHSVGGLLEVYVSA", "length": 600, "header": "tr|A0A8V1APS5-1|A0A8V1AEM0_CHICK Computationally mapped isoform of Otopetrin 3 OS=Gallus gallus OX=9031 GN=OTOP3 PE=3 SV=1 CANONICAL=A0A8V1AEM0-1" }, "locus": { "chromosome": "18", "start_pos": 11200296, "end_pos": 11195622, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071787.1", "url": "https://www.ensembl.org/id/ENSGALT00010071787.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044477.1", "url": "https://www.ensembl.org/id/ENSGALP00010044477.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:422112", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422112", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2JTK7-1", "protein_name": "Otopetrin 3", "gene_name": "Otop3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASQTSAPEPAPMPSSEAETTEAASTYDQANMDVETKHTGPPGAPKQKSWLALHFSLLLRRDRQAQKAGQLFSGLLALNVVFLGGAFICSMIFNKVAVTLGDVWILLAALKVLSLLWLLYYTVGTTRKPHAVLYRDPHAGPVWVRGSLVLFGSCTVCLNVFRMGYDVSHIHCKSEVELIFPAIEIVFMIIQTWVLWKHCKDCVQVQTNFTRCGLMLTLATNLLMWVLAVTNDSMHREIEAELDALMEKFSGNGTNTCMCLNATVCEVFRKGFLMLYPFSTEYCLICCAVLFVMWKNVGRSLAAHSGAHPNRPPFRLHGAIFGPLLGLLALVAGVCVFVLFQIEASGPDIARQYFTLYYAFYVAVLPTMSLACLAGTAIHGLEERELDTLKNPTRSLDVVLLMGAALGQMGIAYFSIVAIVATQPHQLLNQLILAYSLLLILQHITQNLFIIEGLHRRPLWEPVISGVPEKQDIELPRRGSLRELGQDLRRASRAYIHSFSHLNWKRRMLKEISLFLILCNITLWMMPAFGIHPEFENGLEKDFYGYRTWFTIVNFGLPLGVFYRMHSVGGLVEVYLGA", "length": 578 }, "evidence": [ { "id": "A0A8V1AEM0", "url": "https://omabrowser.org/oma/group/A0A8V1AEM0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1RVV5-1", "protein_name": "Otopetrin 3", "gene_name": "OTOP3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPAPASAPTEALPVVSPEAQEPGKTPAKESQAAMGAEGTKAPAPPVQKSWLVRHFSLLLRRDRQAQKAGQLFSGLLALNVVFLGGAFICSMIFNNVAITLGDVWILLATLKSLSLLWLLYYTAGTTRRPHAVPHQDPHAGPIWVLGSLVLFGSCTICLNIFRVGYDISHSGCKSQLELIFPAIEIIFMGVQTWVLWKHCKDCVQVQTNFTRCGLMLTLATNLLLWLLAVTNDSMHHEIESELNTLVKKFSGNDTNTCLCLNVTMCKVFQKGYLMLYPFSTEYCLICCAVLFVMWKNVGRRLASHVDGHPRTPPFHLHGAIFGPLLGLLVLVAGVCVFVLFQIQASGPAIARQYFTIYYAFYVAVLPAMSLACLAGTAIHGLEERELDTLKNPTRSLDVMLLMGAALGQIGISYFSIVAIVATRPHELLNRLILAYSLLLILQHIAQNLFIIEGLHRRPLWEAAPESLAGKREAEPPRRGSLLELGQDLRRASLAYIHSYSHLNWKRRALKEISLFLILCNITLWMMPAFGIHPEFENGLEKDFYGYRTWFTIVNFGLPLGVFYRMHSVGGLVEVYLGA", "length": 578 }, "evidence": [ { "id": "A0A8V1AEM0", "url": "https://omabrowser.org/oma/group/A0A8V1AEM0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q7RTS5-1", "protein_name": "Proton channel OTOP3", "gene_name": "OTOP3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGRGARAAAAQSRWGRASRASVSPGRTIRSAPAVGEAQETEAAPEKENRVDVGAEERAAATRPRQKSWLVRHFSLLLRRDRQAQKAGQLFSGLLALNVVFLGGAFICSMIFNKVAVTLGDVWILLATLKVLSLLWLLYYVASTTRRPHAVLYQDPHAGPLWVRGSLVLFGSCTFCLNIFRVGYDVSHIRCKSQLDLVFSVIEMVFIGVQTWVLWKHCKDCVRVQTNFTRCGLMLTLATNLLLWVLAVTNDSMHREIEAELGILMEKSTGNETNTCLCLNATACEAFRRGFLMLYPFSTEYCLICCAVLFVMWKNVGRHVAPHMGAHPATAPFHLHGAIFGPLLGLLVLLAGVCVFVLFQIEASGPAIACQYFTLYYAFYVAVLPTMSLACLAGTAIHGLEERELDTVKNPTRSLDVVLLMGAALGQMGIAYFSIVAIVAKRPHELLNRLILAYSLLLILQHIAQNLFIIEGLHRRPLWETVPEGLAGKQEAEPPRRGSLLELGQGLQRASLAYIHSYSHLNWKRRALKEISLFLILCNITLWMMPAFGIHPEFENGLEKDFYGYQIWFAIVNFGLPLGVFYRMHSVGGLVEVYLGA", "length": 596 }, "evidence": [ { "id": "A0A8V1AEM0", "url": "https://omabrowser.org/oma/group/A0A8V1AEM0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q80UF9-1", "protein_name": "Proton channel OTOP3", "gene_name": "Otop3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASQTSAPAEPAPMPSPEAKTTEGASSYDQADMETKHAGSPCPPKQKSWLARHFSLLLRRDRQAQKAGQLFSGLLALNVVFLGGAFICSMIFNKVSVTLGDVWILLAALKVLSLLWLLYYTVGTTRKPHAVLYRDPHAGPIWVRGSLVLFGSCTVCLNIFRMGYDVSHIHCKSEVELIFPAIEIVFMIIQTWVLWRHCKDCVQVQTNFTRCGLMLTLATNLLMWVLAVTNDSMHREIEAELDALMEKFSGNGTNTCMCLNTTVCEVFRKGYLMLYPFSTEYCLICCAVLFVMWKNVSRSLAAHTGAHPNRSPFRLHGTIFGPLLGLLALVAGVCVFVLFQIEASGPDIARQYFTLYYAFYVAVLPTMSLACLAGTAIHGLEERELDTLKNPTRSLDVVLLMGAALGQMGIAYFSIVAIVATQPHELLNQLILAYSLLLILQHITQNLFIIEGLHRRPLWEPAVSGVMEKQDVELPRRGSLRELGQDLRRASRAYIHSFSHLNWKRRMLKEISLFLILCNITLWMMPAFGIHPEFENGLEKDFYGYRTWFTIVNFGLPLGVFYRMHSVGGLVEVYLGA", "length": 577 }, "evidence": [ { "id": "A0A8V1AEM0", "url": "https://omabrowser.org/oma/group/A0A8V1AEM0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEM0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEM0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEM0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEM0" } ], "pmid": "" }, { "name": "proton channel activity", "id": "GO:0015252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015252", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEM0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEM0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "proton transmembrane transport", "id": "GO:1902600", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902600", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEM0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEM0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 192, "end_pos": 194, "annotation": "n_glycosylation_sequon" }, { "start_pos": 215, "end_pos": 217, "annotation": "n_glycosylation_sequon" }, { "start_pos": 251, "end_pos": 253, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 192, "end_pos": 194 }, { "start_pos": 215, "end_pos": 217 }, { "start_pos": 251, "end_pos": 253 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", 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"sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AB65-1", "uniprot_ac": "A0A8V1AB65", "uniprot_id": "A0A8V1AB65_CHICK", "mass": { "chemical_mass": 18915.0, "monoisotopic_mass": 18915.0 }, "refseq": { "ac": "NP_001383459", "name": "CCHC-type zinc finger nucleic acid binding protein isoform 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001383459" }, "gene_names": [ { "name": "CNBP", "type": "recommended", "evidence": [ { "id": "A0A8V1AB65", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB65" } ] }, { "name": "CNBP", "type": "synonym", "evidence": [ { "id": "NP_001383459", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001383459" } ] }, { "name": "ZCCHC13", "type": "synonym", "evidence": [ { "id": "NP_001383459", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001383459" } ] }, { "name": "ZNF9", "type": "synonym", "evidence": [ { "id": "NP_001383459", "database": "RefSeq", "url": 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"database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADJ2/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADJ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADJ2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "UBAP2L", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADJ2", "locus": { "chromosome": "25", "start_pos": 1920094, "end_pos": 1897735, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027867", "url": "https://www.ensembl.org/id/ENSGALG00010027867" } ] } } ], "crossref": [ { "id": "A0A8V1ADJ2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1ADJ2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000024094", "url": 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{ "id": "IPR060532", "url": "https://www.ebi.ac.uk/interpro/entry/IPR060532", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "H9L3J8", "url": "https://www.orthodb.org/?gene=H9L3J8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16308", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16308", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16308:SF18", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16308:SF18", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12478", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12478", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF28540", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF28540", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1A5V3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5V3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A5V3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5V3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ADJ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADJ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ADJ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADJ2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AG35", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG35", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AG35-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG35-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHY4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHY4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHY4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHY4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "H9L3J8", "url": "https://www.uniprot.org/uniprotkb/H9L3J8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "H9L3J8-1", "url": "https://www.uniprot.org/uniprotkb/H9L3J8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMTSVGTNRARGSWEQTQTQSQTQHKQRPQATAEQIRLAQMISDHNDADFEEKVKQLIDITGKNQDECVIALHDCNGDVNRAINVLLEGNPDTHSWEMVGKKKGVSGQKDSGQTEPSEESKENRERDRDFSRRRGGPPRRGRGASRGREFRGQENGLDGGKSGGSSGRGTERGRRGRGRGRGGSGRRGGRFSAQGMGTFNPADYAEPTSTDESYGNSNTNTWNNTGSFEPDDGTSAWRAATEEWGTEDWNEDLSETKIFTASNVSSVPLPTENVTITAGQRIDLAVLLGKTPSSMENESTNLESSQAPSLAQPLVFSNSKQSAISQPASGNSFSHHSMVSMLGKGFGDVGEAKGSSTTGSQFLEQFKTAQALAQLAAQHSQPGSSTAASSWDMGSATQTSSLVQYDLKNPADSSVHSPFAKRQAFTSTSTMIEVFMQEKQPVVTASTTVPAPPSSPLPSKANPVPQMSPGSSDNQSSSPQPAQQKLKQQKKKASLTSKIPALAVEMPGSADISGLNLQFGALQFGSEPVLAEYESTPTTSAAVSQPQSSLYTSTASESSSTISSNQSQESGYQSGTIQTATFTSQNSAQGPLYEQRSTQTRRYPNSISSSPQKDLTQAKNGFSSVQPTPLQSTQAVEGATGPAVKSDSPSAPSMAPLNDGVSAASLLSTASQHSTALSSLSHSEELPSTTAAQLSSTLPTQQNSLSSSTSSGRTSTSTLLHTSVESEASLHSSASTFSTSSSTVSAAPPVVSVSSSLSSVSSLGLSLSSNSTVTASTRSSVATTSGKAPPNLPPGVPPLLPNPYIMAPGLLHAYPVYGYDDLQMLQTRFPLDYYSIPFPTPTTPLTGRDGSLSSNPYSGDLTKFGRGDASSPAPATTLAQPQQSQTQTHHTTQQTFLNPALPPGYSYTSLPYYTGVPGLPSTFQYGPAVFPVAPTSSKQHGVNVSVNASATPFQQPSGYGSHGYSAGVSVTSSNTGVPDISGSVYSKTQQSFEKQGFHTGTPAASFNLPSALGSGGPINPATAAAYPPTPFMHILTPHQQPHSQILHHHLQQDGQSGSGQRSQGSSIPQKSQANKSAYNSYSWGTN", "length": 1086, "header": "tr|A0A8V1ADJ2-1|A0A8V1ADJ2_CHICK Isoform 1 of Ubiquitin associated protein 2 like OS=Gallus gallus OX=9031 GN=UBAP2L PE=1 SV=1 CANONICAL=A0A8V1ADJ2-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A5V3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADJ2/entry#A0A8V1A5V3-1", "sequence": { "sequence": "MMTSVGTNRARGSWEQTQTQSQTQHKQRPQATAEQIRLAQMISDHNDADFEEKVKQHSWEMVGKKKGVSGQKDSGQTEPSEESKENRERDRDFSRRRGGPPRRGRGASRGREFRGQENGLDGGKSGGSSGRGTERGRRGRGRGRGGSGRRGGRFSAQGMGTFNPADYAEPTSTDESYGNSNTNTWNNTGSFEPDDGTSAWRAATEEWGTEDWNEDLSETKIFTASNVSSVPLPTENVTITAGQRIDLAVLLGKTPSSMENESTNLESSQAPSLAQPLVFSNSKQSAISQPASGNSFSHHSMVSMLGKGFGDVGEAKGSSTTGSQFLEQFKTAQALAQLAAQHSQPGSSTAASSWDMGSATQTSSLVQYDLKNPADSSVHSPFAKRQAFTSTSTMIEVFMQEKQPVVTASTTVPAPPSSPLPSKANPVPQMSPGSSDNQSSSPQPAQQKLKQQKKKASLTSKIPALAVEMPGSADISGLNLQFGALQFGSEPVLAEYESTPTTSAAVSQPQSSLYTSTASESSSTISSNQSQESGYQSGTIQTATFTSQNSAQGPLYEQRSTQTRRYPNSISSSPQKDLTQAKNGFSSVQPTPLQSTQAVEGATGPAVKSDSPSAPSMAPLNDGVSAASLLSTASQHSTALSSLSHSEELPSTTAAQLSSTLPTQQNSLSSSTSSGRTSTSTLLHTSVESEASLHSSASTFSTSSSTVSAAPPVVSVSSSLSSVSSLGLSLSSNSTVTASTRSSVATTSGKAPPNLPPGVPPLLPNPYIMAPGLLHAYPPQVYGYDDLQMLQTRFPLDYYSIPFPTPTTPLTGRDGSLSSNPYSGDLTKFGRGDASSPAPATTLAQPQQSQTQTHHTTQQTFLNPALPPGYSYTSLPYYTGVPGLPSTFQYGPAVFPVAPTSSKQHGVNVSVNASATPFQQPSGYGSHGYSAGVSVTSSNTGVPDISGSVYSKTQQSFEKQGFHTGTPAASFNLPSALGSGGPINPATAAAYPPTPFMHILTPHQQPHSQILHHHLQQDGQSGSGQRSQGSSIPQKSQANKSAYNSYSWGTN", "length": 1051, "header": "tr|A0A8V1A5V3-1|A0A8V1ADJ2_CHICK Computationally mapped isoform of Ubiquitin associated protein 2 like OS=Gallus gallus OX=9031 GN=UBAP2L PE=1 SV=1 CANONICAL=A0A8V1ADJ2-1" }, "locus": { "chromosome": "25", "start_pos": 1919347, "end_pos": 1900392, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067539.1", "url": "https://www.ensembl.org/id/ENSGALT00010067539.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041282.1", "url": "https://www.ensembl.org/id/ENSGALP00010041282.1" } ] } }, { "isoform_ac": "A0A8V1ADJ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADJ2/entry#A0A8V1ADJ2-1", "sequence": { "sequence": "MMTSVGTNRARGSWEQTQTQSQTQHKQRPQATAEQIRLAQMISDHNDADFEEKVKQLIDITGKNQDECVIALHDCNGDVNRAINVLLEGNPDTHSWEMVGKKKGVSGQKDSGQTEPSEESKENRERDRDFSRRRGGPPRRGRGASRGREFRGQENGLDGGKSGGSSGRGTERGRRGRGRGRGGSGRRGGRFSAQGMGTFNPADYAEPTSTDESYGNSNTNTWNNTGSFEPDDGTSAWRAATEEWGTEDWNEDLSETKIFTASNVSSVPLPTENVTITAGQRIDLAVLLGKTPSSMENESTNLESSQAPSLAQPLVFSNSKQSAISQPASGNSFSHHSMVSMLGKGFGDVGEAKGSSTTGSQFLEQFKTAQALAQLAAQHSQPGSSTAASSWDMGSATQTSSLVQYDLKNPADSSVHSPFAKRQAFTSTSTMIEVFMQEKQPVVTASTTVPAPPSSPLPSKANPVPQMSPGSSDNQSSSPQPAQQKLKQQKKKASLTSKIPALAVEMPGSADISGLNLQFGALQFGSEPVLAEYESTPTTSAAVSQPQSSLYTSTASESSSTISSNQSQESGYQSGTIQTATFTSQNSAQGPLYEQRSTQTRRYPNSISSSPQKDLTQAKNGFSSVQPTPLQSTQAVEGATGPAVKSDSPSAPSMAPLNDGVSAASLLSTASQHSTALSSLSHSEELPSTTAAQLSSTLPTQQNSLSSSTSSGRTSTSTLLHTSVESEASLHSSASTFSTSSSTVSAAPPVVSVSSSLSSVSSLGLSLSSNSTVTASTRSSVATTSGKAPPNLPPGVPPLLPNPYIMAPGLLHAYPVYGYDDLQMLQTRFPLDYYSIPFPTPTTPLTGRDGSLSSNPYSGDLTKFGRGDASSPAPATTLAQPQQSQTQTHHTTQQTFLNPALPPGYSYTSLPYYTGVPGLPSTFQYGPAVFPVAPTSSKQHGVNVSVNASATPFQQPSGYGSHGYSAGVSVTSSNTGVPDISGSVYSKTQQSFEKQGFHTGTPAASFNLPSALGSGGPINPATAAAYPPTPFMHILTPHQQPHSQILHHHLQQDGQSGSGQRSQGSSIPQKSQANKSAYNSYSWGTN", "length": 1086, "header": "tr|A0A8V1ADJ2-1|A0A8V1ADJ2_CHICK Isoform 1 of Ubiquitin associated protein 2 like OS=Gallus gallus OX=9031 GN=UBAP2L PE=1 SV=1 CANONICAL=A0A8V1ADJ2-1" }, "locus": { "chromosome": "25", "start_pos": 1919347, "end_pos": 1900392, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067543.1", "url": "https://www.ensembl.org/id/ENSGALT00010067543.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041286.1", "url": "https://www.ensembl.org/id/ENSGALP00010041286.1" } ] } }, { "isoform_ac": "A0A8V1AG35-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADJ2/entry#A0A8V1AG35-1", "sequence": { "sequence": "MMTSVGTNRARGSWEQTQTQSQTQHKQRPQATAEQIRLAQMISDHNDADFEEKVKQLIDITGKNQDECVIALHDCNGDVNRAINVLLEGNPDTHSWEMVGKKKGVSGQKDSGQTEPSEESKENRERDRDFSRRRGGPPRRGRGASRGREFRGQENGLDGGKSGGSSGRGTERGRRGRGRGRGGSGRRGGRFSAQGMGTFNPADYAEPTSTDESYGNSNTNTWNNTGSFEPDDGTRLDFIGGAWRAATEEWGTEDWNEDLSETKIFTASNVSSVPLPTENVTITAGQRIDLAVLLGKTPSSMENESTNLESSQAPSLAQPLVFSNSKQSAISQPASGNSFSHHSMVSMLGKGFGDVGEAKGSSTTGSQFLEQFKTAQALAQLAAQHSQPGSSTAASSWDMGSATQTSSLVQYDLKNPADSSVHSPFAKRQAFTSTSTMIEVFMQEKQPVVTASTTVPAPPSSPLPSKANPVPQMSPGSSDNQSSSPQPAQQKLKQQKKKASLTSKIPALAVEMPGSADISGLNLQFGALQFGSEPVLAEYESTPTTSAAVSQPQSSLYTSTASESSSTISSNQSQESGYQSGTIQTATFTSQNSAQGPLYEQRSTQTRRYPNSISSSPQKDLTQAKNGFSSVQPTPLQSTQAVEGATGPAVKSDSPSAPSMAPLNDGVSAASLLSTASQHSTALSSLSHSEELPSTTAAQLSSTLPTQQNSLSSSTSSGRTSTSTLLHTSVESEASLHSSASTFSTSSSTVSAAPPVVSVSSSLSSVSSLGLSLSSNSTVTASTRSSVATTSGKAPPNLPPGVPPLLPNPYIMAPGLLHAYPPQVYGYDDLQMLQTRFPLDYYSIPFPTPTTPLTGRDGSLSSNPYSGDLTKFGRGDASSPAPATTLAQPQQSQTQTHHTTQQTFLNPALPPGYSYTSLPYYTGVPGLPSTFQYGPAVFPVAPTSSKQHGVNVSVNASATPFQQPSGYGSHGYSAGVSVTSSNTGVPDISGSVYSKTQQSFEKQGFHTGTPAASFNLPSALGSGGPINPATAAAYPPTPFMHILTPHQQPHSQILHHHLQQDGQLPYLQMILCCQRQQEDQSGSGQRSQGSSIPQKSQANKSAYNSYSWGTN", "length": 1111, "header": "tr|A0A8V1AG35-1|A0A8V1ADJ2_CHICK Computationally mapped isoform of Ubiquitin associated protein 2 like OS=Gallus gallus OX=9031 GN=UBAP2L PE=1 SV=1 CANONICAL=A0A8V1ADJ2-1" }, "locus": { "chromosome": "25", "start_pos": 1919347, "end_pos": 1900392, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067537.1", "url": "https://www.ensembl.org/id/ENSGALT00010067537.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041280.1", "url": "https://www.ensembl.org/id/ENSGALP00010041280.1" } ] } }, { "isoform_ac": "A0A8V1AHY4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADJ2/entry#A0A8V1AHY4-1", "sequence": { "sequence": "MMTSVGTNRARGSWEQTQTQSQTQHKQRPQATAEQIRLAQMISDHNDADFEEKVKQLIDITGKNQDECVIALHDCNGDVNRAINVLLEGNPDTHSWEMVGKKKGVSGQKDSGQTEPSEESKENRERDRDFSRRRGGPPRRGRGASRGREFRGQENGLDGGKSGGSSGRGTERGRRGRGRGRGGSGRRGGRFSAQGMGTFNPADYAEPTSTDESYGNSNTNTWNNTGSFEPDDGTRLDFIGGAWRAATEEWGTEDWNEDLSETKIFTASNVSSVPLPTENVTITAGQRIDLAVLLGKTPSSMENESTNLESSQAPSLAQPLVFSNSKQSAISQPASGNSFSHHSMVSMLGKGFGDVGEAKGSSTTGSQFLEQFKTAQALAQLAAQHSQPGSSTAASSWDMGSATQTSSLVQYDLKNPADSSVHSPFAKRQAFTSTSTMIEVFMQEKQPVVTASTTVPAPPSSPLPSKANPVPQMSPGSSDNQSSSPQPAQQKLKQQKKKASLTSKIPALAVEMPGSADISGLNLQFGALQFGSEPVLAEYESTPTTSAAVSQPQSSLYTSTASESSSTISSNQSQESGYQSGTIQTATFTSQNSAQGPLYEQRSTQTRRYPNSISSSPQKDLTQAKNGFSSVQPTPLQSTQAVEGATGPAVKSDSPSAPSMAPLNDGVSAASLLSTASQHSTALSSLSHSEELPSTTAAQLSSTLPTQQNSLSSSTSSGRTSTSTLLHTSVESEASLHSSASTFSTSSSTVSAAPPVVSVSSSLSSVSSLGLSLSSNSTVTASTRSSVATTSGKAPPNLPPGVPPLLPNPYIMAPGLLHAYPPQVYGYDDLQMLQTRFPLDYYSIPFPTPTTPLTGRDGSLSSNPYSGDLTKFGRGDASSPAPATTLAQPQQSQTQTHHTTQQTFLNPALPPGYSYTSLPYYTGVPGLPSTFQYGPAVFPVAPTSSKQHGVNVSVNASATPFQQPSGYGSHGYSAGVSVTSSNTGVPDISGSVYSKTQQSFEKQGFHTGTPAASFNLPSALGSGGPINPATAAAYPPTPFMHILTPHQQPHSQILHHHLQQDGQGR", "length": 1065, "header": "tr|A0A8V1AHY4-1|A0A8V1ADJ2_CHICK Computationally mapped isoform of Ubiquitin associated protein 2 like OS=Gallus gallus OX=9031 GN=UBAP2L PE=1 SV=1 CANONICAL=A0A8V1ADJ2-1" }, "locus": { "chromosome": "25", "start_pos": 1918572, "end_pos": 1900392, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067535.1", "url": "https://www.ensembl.org/id/ENSGALT00010067535.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041278.1", "url": "https://www.ensembl.org/id/ENSGALP00010041278.1" } ] } }, { "isoform_ac": "H9L3J8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADJ2/entry#H9L3J8-1", "sequence": { "sequence": "MMTSVGTNRARGSWEQTQTQSQTQHKQRPQATAEQIRLAQMISDHNDADFEEKVKQLIDITGKNQDECVIALHDCNGDVNRAINVLLEGNPDTHSWEMVGKKKGVSGQKDSGQTEPSEESKENRERDRDFSRRRGGPPRRGRGASRGREFRGQENGLDGGKSGGSSGRGTERGRRGRGRGRGGSGRRGGRFSAQGMGTFNPADYAEPTSTDESYGNSNTNTWNNTGSFEPDDGTRLDFIGGEGSNYPRKFDSAPGTIHPGAWRAATEEWGTEDWNEDLSETKIFTASNVSSVPLPTENVTITAGQRIDLAVLLGKTPSSMENESTNLESSQAPSLAQPLVFSNSKQSAISQPASGNSFSHHSMVSMLGKGFGDVGEAKGSSTTGSQFLEQFKTAQALAQLAAQHSQPGSSTAASSWDMGSATQTSSLVQYDLKNPADSSVHSPFAKRQAFTSTSTMIEVFMQEKQPVVTASTTVPAPPSSPLPSKANPVPQMSPGSSDNQSSSPQPAQQKLKQQKKKASLTSKIPALAVEMPGSADISGLNLQFGALQFGSEPVLAEYESTPTTSAAVSQPQSSLYTSTASESSSTISSNQSQESGYQSGTIQTATFTSQNSAQGPLYEQRSTQTRRYPNSISSSPQKDLTQAKNGFSSVQPTPLQSTQAVEGATGPAVKSDSPSAPSMAPLNDGVSAASLLSTASQHSTALSSLSHSEELPSTTAAQLSSTLPTQQNSLSSSTSSGRTSTSTLLHTSVESEASLHSSASTFSTSSSTVSAAPPVVSVSSSLSSVSSLGLSLSSNSTVTASTRSSVATTSGKAPPNLPPGVPPLLPNPYIMAPGLLHAYPPQVYGYDDLQMLQTRFPLDYYSIPFPTPTTPLTGRDGSLSSNPYSGDLTKFGRGDASSPAPATTLAQPQQSQTQTHHTTQQTFLNPALPPGYSYTSLPYYTGVPGLPSTFQYGPAVFPVAPTSSKQHGVNVSVNASATPFQQPSGYGSHGYSAGVSVTSSNTGVPDISGSVYSKTQQSFEKQGFHTGTPAASFNLPSALGSGGPINPATAAAYPPTPFMHILTPHQQPHSQILHHHLQQDGQSGSGQRSQGSSIPQKSQANKSAYNSYSWGTN", "length": 1113, "header": "tr|H9L3J8-1|A0A8V1ADJ2_CHICK Computationally mapped isoform of Ubiquitin associated protein 2 like OS=Gallus gallus OX=9031 GN=UBAP2L PE=1 SV=4 CANONICAL=A0A8V1ADJ2-1" }, "locus": { "chromosome": "25", "start_pos": 1919347, "end_pos": 1900392, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067546.1", "url": "https://www.ensembl.org/id/ENSGALT00010067546.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041289.1", "url": "https://www.ensembl.org/id/ENSGALP00010041289.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 840, "start_aa": "Thr", "end_pos": 840, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr840", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 935, "start_aa": "Thr", "end_pos": 935, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr935", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADJ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADJ2" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADJ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADJ2" } ], "pmid": "" }, { "name": "chromosome", "id": "GO:0005694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005694", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADJ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADJ2" } ], "pmid": "" }, { "name": "PcG protein complex", "id": "GO:0031519", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031519", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADJ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADJ2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "hematopoietic stem cell homeostasis", "id": "GO:0061484", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061484", 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"MHRAARAFGEYLSQNHPEGRNGSDHLLADSYIGQEDSPEMQQAAQNKRRLSVISDGKFERSFSEEQTEKMPSEGPKPRVYTISGERPMLSDHENESMELVVMKGAAQEECHHGHPVHGAGGSHGVSRHCKGWPGSRQGSKECPNCTRLAAPSHHSFDLEPHQSGETGWHRKRLERMYSVDRVSDDVPIRTWFPKENLFSFQTATTTMQAAFRGYAERKRRKRENDSAAVIQRNFRKHLRMVGSRRVKAQTFAERRERSFSRSWSDPTPIKADSFHDSRESHDLQDSCGTLDGDFDLNWEAEKELEAMACDGEDFIPPKIMLISSKVPKAEYVPTIIRRDDPSIIPILYDHEHATFDDILEEIEKKLNIYRKGCKIWKMLIFCQGGPGHLYLLKNKVATFAKVEKEEDMILFWKRLSRLMSKINPEPNIIHIMGCYVLGNPNGEKLFQNLKNLMNPYRVAFESPLELSAQGKQMIETYFDFRLYRLWKTRQHSKLLDYDDIL", "length": 501, "header": "tr|A0A8V1ADI8-1|A0A8V1ADI8_CHICK Isoform 1 of NMDA receptor synaptonuclear signaling and neuronal migration factor OS=Gallus gallus OX=9031 GN=NSMF PE=1 SV=1 CANONICAL=A0A8V1ADI8-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AAR6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADI8/entry#A0A8V1AAR6-1", "sequence": { "sequence": "MSAPPAVIPRANMGTAVSKRKTLRNEAMSSVAAKVRAARAFGEYLSQNHPEGRNGSDHLLADSYIGQEDSPEMQQAAQNKRRLSVISDGKFERSFSEEQTEKMPSEGPKPRVYTISGERPMLSDHENESMELVVMKGAAQEECHHGHPVHGAGGSHGVSRHCKGWPGSRQGSKECPNCTRLAAPSHHSFDLEPHQSGETGWHRKRLERMYSVDRVSDDVPIRTWFPKENLFSFQTATTTMQAISAFRGYAERKRRKRENDSAAVIQRNFRKHLRMVGSRRVKAQSHDLQDSCGTLDGDFDLNWEAEKELEAMACDGEDFIPPKIMLISSKVPKAEYVPTIIRRDDPSIIPILYDHEHATFDDILEEIEKKLNIYRKGCKIWKMLIFCQGGPGHLYLLKNKVATFAKVEKEEDMILFWKRLSRLMSKINPEPNIIHIMGCYVLGNPNGEKLFQNLKNLMNPYRVAFESPLELSAQGKQMIETYFDFRLYRLWKTRQHSKLLDYDDIL", "length": 506, "header": "tr|A0A8V1AAR6-1|A0A8V1ADI8_CHICK Computationally mapped isoform of NMDA receptor synaptonuclear signaling and neuronal migration factor OS=Gallus gallus OX=9031 GN=NSMF PE=1 SV=1 CANONICAL=A0A8V1ADI8-1" }, "locus": { "chromosome": "17", "start_pos": 2431851, "end_pos": 2392952, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067541.1", "url": "https://www.ensembl.org/id/ENSGALT00010067541.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041284.1", "url": "https://www.ensembl.org/id/ENSGALP00010041284.1" } ] } }, { "isoform_ac": "A0A8V1ADI8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADI8/entry#A0A8V1ADI8-1", "sequence": { "sequence": "MHRAARAFGEYLSQNHPEGRNGSDHLLADSYIGQEDSPEMQQAAQNKRRLSVISDGKFERSFSEEQTEKMPSEGPKPRVYTISGERPMLSDHENESMELVVMKGAAQEECHHGHPVHGAGGSHGVSRHCKGWPGSRQGSKECPNCTRLAAPSHHSFDLEPHQSGETGWHRKRLERMYSVDRVSDDVPIRTWFPKENLFSFQTATTTMQAAFRGYAERKRRKRENDSAAVIQRNFRKHLRMVGSRRVKAQTFAERRERSFSRSWSDPTPIKADSFHDSRESHDLQDSCGTLDGDFDLNWEAEKELEAMACDGEDFIPPKIMLISSKVPKAEYVPTIIRRDDPSIIPILYDHEHATFDDILEEIEKKLNIYRKGCKIWKMLIFCQGGPGHLYLLKNKVATFAKVEKEEDMILFWKRLSRLMSKINPEPNIIHIMGCYVLGNPNGEKLFQNLKNLMNPYRVAFESPLELSAQGKQMIETYFDFRLYRLWKTRQHSKLLDYDDIL", "length": 501, "header": "tr|A0A8V1ADI8-1|A0A8V1ADI8_CHICK Isoform 1 of NMDA receptor synaptonuclear signaling and neuronal migration factor OS=Gallus gallus OX=9031 GN=NSMF PE=1 SV=1 CANONICAL=A0A8V1ADI8-1" }, "locus": { "chromosome": "17", "start_pos": 2431851, "end_pos": 2400506, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067538.1", "url": "https://www.ensembl.org/id/ENSGALT00010067538.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041281.1", "url": "https://www.ensembl.org/id/ENSGALP00010041281.1" } ] } }, { "isoform_ac": "A0A8V1AG40-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADI8/entry#A0A8V1AG40-1", "sequence": { "sequence": "MSAPPAVIPRANMGTAVSKRKTLRNEAMSSVAAKVRAARAFGEYLSQNHPEGRNGSDHLLADSYIGQEDSPEMQQAAQNKRRLSVISDGKFERSFSEEQTEKMPSEGPKPRVYTISGERPMLSDHENESMELVVMKGAAQEECHHGHPVHGAGGSHGVSRHCKGWPGSRQGSKECPNCTRLAAPSHHSFDLEPHQSGETGWHRKRLERMYSVDRVSDDVPIRTWFPKENLFSFQTATTTMQAISNFRKHLRMVGSRRVKAQTFAERRERSFSRSWSDPTPIKADSFHDSRESHDLQDSCGTLDGDFDLNWEAEKELEAMACDGEDFIPPKIMLISSKVPKAEYVPTIIRRDDPSIIPILYDHEHATFDDILEEIEKKLNIYRKGCKIWKMLIFCQGGPGHLYLLKNKVATFAKVEKEEDMILFWKRLSRLMSKINPEPNIIHIMGCYVLGNPNGEKLFQNLKNLMNPYRVAFESPLELSAQGKQMIETYFDFRLYRLWKTRQHSKLLDYDDIL", "length": 513, "header": "tr|A0A8V1AG40-1|A0A8V1ADI8_CHICK Computationally mapped isoform of NMDA receptor synaptonuclear signaling and neuronal migration factor OS=Gallus gallus OX=9031 GN=NSMF PE=1 SV=1 CANONICAL=A0A8V1ADI8-1" }, "locus": { "chromosome": "17", "start_pos": 2431851, "end_pos": 2392952, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067542.1", "url": "https://www.ensembl.org/id/ENSGALT00010067542.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041285.1", "url": "https://www.ensembl.org/id/ENSGALP00010041285.1" } ] } }, { "isoform_ac": "A0A8V1AHZ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADI8/entry#A0A8V1AHZ2-1", "sequence": { "sequence": "MSAPPAVIPRANMGTAVSKRKTLRNEAMSSVAAKVRAARAFGEYLSQNHPEGRNGSDHLLADSYIGQEDSPEMQQAAQNKRRLSVISDGKFERSFSEEQTEKMPSEGPKPRVYTISGERPMLSDHENESMELVVMKGAAQEECHHGHPVHGAGGSHGVSRHCKGWPGSRQGSKECPNCTRLAAPSHHSFDLEPHQSGETGWHRKRLERMYSVDRVSDDVPIRTWFPKENLFSFQTATTTMQANFRKHLRMVGSRRVKAQTFAERRERSFSRSWSDPTPIKADSFHDSRESHDLQDSCGTLDGDFDLNWEAEKELEAMACDGEDFIPPKIMLISSKVPKAEYVPTIIRRDDPSIIPILYDHEHATFDDILEEIEKKLNIYRKGCKIWKMLIFCQGGPGHLYLLKNKVATFAKVEKEEDMILFWKRLSRLMSKINPEPNIIHIMGCYVLGNPNGEKLFQNLKNLMNPYRVAFESPLELSAQGKQMIETYFDFRLYRLWKTRQHSKLLDYDDIL", "length": 511, "header": "tr|A0A8V1AHZ2-1|A0A8V1ADI8_CHICK Computationally mapped isoform of NMDA receptor synaptonuclear signaling and neuronal migration factor OS=Gallus gallus OX=9031 GN=NSMF PE=1 SV=1 CANONICAL=A0A8V1ADI8-1" }, "locus": { "chromosome": "17", "start_pos": 2431851, "end_pos": 2392952, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067545.1", "url": "https://www.ensembl.org/id/ENSGALT00010067545.1" }, { "database": "Ensembl 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"pmid": "" }, { "name": "ERAD pathway", "id": "GO:0036503", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036503", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AC80", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC80" } ], "pmid": "" }, { "name": "negative regulation of ubiquitin-dependent protein catabolic process", "id": "GO:2000059", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000059", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AC80", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC80" } ], "pmid": "" }, { "name": "tail-anchored membrane protein insertion into ER membrane", "id": "GO:0071816", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071816", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AC80", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC80" } ], "pmid": "" }, { "name": "positive regulation of ERAD pathway", "id": "GO:1904294", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904294", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AC80", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC80" } ], "pmid": "" }, { "name": "positive regulation of ubiquitin-dependent protein catabolic process", "id": "GO:2000060", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000060", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AC80", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC80" } ], "pmid": "" }, { "name": "negative regulation of ERAD pathway", "id": "GO:1904293", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904293", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AC80", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC80" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "molecular adaptor activity", "id": "GO:0060090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060090", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AC80", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC80" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AC80", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC80" } ], "pmid": "" }, { "name": "BAT3 complex binding", "id": "GO:1904288", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904288", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AC80", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC80" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AC80", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC80" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AC80", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC80" } ], "pmid": "" }, { "name": "TRC complex", "id": "GO:0072380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072380", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AC80", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC80" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AC80", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC80" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AC80", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC80" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 156, "end_pos": 158, "annotation": "n_glycosylation_sequon" }, { "start_pos": 191, "end_pos": 193, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AC80", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC80" }, { "id": "PF16546", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16546" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SGTA homodimerisation", "eco_id": "ECO_0000259", "start_pos": 4, "end_pos": 63, "start_aa": "Gln", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 81, 212 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 156, "end_pos": 158 }, { "start_pos": 191, "end_pos": 193 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": 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"table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1ACH1-1", "uniprot_ac": "A0A8V1ACH1", "uniprot_id": "A0A8V1ACH1_CHICK", "mass": { "chemical_mass": 55461.0, "monoisotopic_mass": 55461.0 }, "refseq": { "ac": "XP_015148981", "name": "sodium-coupled neutral amino acid transporter 3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015148981" }, "gene_names": [ { "name": "SLC38A3", "type": "recommended", "evidence": [ { "id": "A0A8V1ACH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACH1" } ] }, { "name": "SLC38A3", "type": "synonym", "evidence": [ { "id": "XP_015148981", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015148981" } ] } ], "protein_names": [ { "name": "Solute carrier family 38 member 3", "type": "synonym", "evidence": [ { "id": "A0A8V1ACH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACH1/entry#names_and_taxonomy" } ] }, { "name": "sodium-coupled neutral amino acid transporter 3", "type": "synonym", "evidence": [ { "id": "XP_015148981", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015148981" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052543.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015148981.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015148981", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015148981" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACH1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACH1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SLC38A3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACH1", "locus": { "chromosome": "12", "start_pos": 3390245, "end_pos": 3399934, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027616", "url": "https://www.ensembl.org/id/ENSGALG00010027616" } ] } } ], "crossref": [ { "id": "A0A8V1ACH1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1ACH1", "database": "AlphaFoldDB", "categories": [] }, { "id": "429200", "url": "https://www.ncbi.nlm.nih.gov/gene/429200", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:429200", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:429200", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MEVAGEM", "url": "https://omabrowser.org/oma/group/MEVAGEM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ACG6", "url": "https://www.orthodb.org/?gene=A0A8V1ACG6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ACH1", "url": "https://www.orthodb.org/?gene=A0A8V1ACH1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AH41", "url": "https://www.orthodb.org/?gene=A0A8V1AH41", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22950", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22950", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22950:SF22", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22950:SF22", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01490", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01490", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-352230", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-352230", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015148981", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015148981", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1ACG6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACG6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ACG6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACG6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ACH1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACH1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ACH1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACH1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AH41", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH41", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AH41-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH41-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEGPELPVQAEMVELVPNGKHAAALGTTTIPSLPGDRFDENQCGAEMEEFLPHGSEKKQTHFTDFEGKTSFGMSVFNLSNAIMGSGILGLAYAMANTGIILFLFLLTAVALLSSYSIHLLLKSSGIVGIRAYEQLGFRAFGTPGKLAAAIAITLQNIGAMSSYLYIVKSEVPLVIQTFLNLEEKTTDWYLNGNYLVILVSVTVILPLALMKQLGYLGYASGFSLSCMVFFLISVIYKKFQIPCPLPEQGGNITSGINVTLGSEHWDGPAAPLPPEVGACTPSFFTLNSQTAYTIPIMAFAFVCHPEVLPIYTELKNPSKKKMQCISNISITVMYLMYFLAALFGYLTFYGRVESELLHTYSRVDPFDVLILCVRVAVLTAVTLTVPIVLFPVRRAIQQMLFQGKNFSWIRHVAIAVILLTFINLLVIFAPSILGIFGLIGATSAPCLIFIFPAIFYIRIMPKDKEPLRSTPKILAACFALLGVLFMIMSLSFIITDWATGGGRSGGSH", "length": 508, "header": "tr|A0A8V1ACH1-1|A0A8V1ACH1_CHICK Isoform 1 of Solute carrier family 38 member 3 OS=Gallus gallus OX=9031 GN=SLC38A3 PE=4 SV=1 CANONICAL=A0A8V1ACH1-1" }, "isoforms": [ { "isoform_ac": "A0A8V1ACG6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACH1/entry#A0A8V1ACG6-1", "sequence": { "sequence": "MRGGCVRCAHPDAACSAGPCSSHPEPDPTPCHATRSPAPAMEGPELPVQAEMVELVPNGKHAAALGTTTIPSLPGDRFDENQCGAEMEEFLPHGSEKKQTHFTDFEGKTSFGMSVFNLSNAIMGSGILGLAYAMANTGIILFLFLLTAVALLSSYSIHLLLKSSGIVGIRAYEQLGFRAFGTPGKLAAAIAITLQNIGAMSSYLYIVKSEVPLVIQTFLNLEEKTTDWYLNGNYLVILVSVTVILPLALMKQLGYLGYASGFSLSCMVFFLISVIYKKFQIPCPLPEQGGNITSGINVTLGSEHWDGPAAPLPPEVGACTPSFFTLNSQTAYTIPIMAFAFVCHPEVLPIYTELKNPSKKKMQCISNISITVMYLMYFLAALFGYLTFYGRVESELLHTYSRVDPFDVLILCVRVAVLTAVTLTVPIVLFPVRRAIQQMLFQGKNFSWIRHVAIAVILLTFINLLVIFAPSILGIFGLIGATSAPCLIFIFPAIFYIRIMPKDKEPLRSTPKILAACFALLGVLFMIMSLSFIITDWATGGGRSGGSH", "length": 548, "header": "tr|A0A8V1ACG6-1|A0A8V1ACG6_CHICK Computationally mapped isoform of Solute carrier family 38 member 3 OS=Gallus gallus OX=9031 GN=SLC38A3 PE=4 SV=1 CANONICAL=A0A8V1ACH1-1" }, "locus": { "chromosome": "12", "start_pos": 3397777, "end_pos": 3391283, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066908.1", "url": "https://www.ensembl.org/id/ENSGALT00010066908.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040928.1", "url": "https://www.ensembl.org/id/ENSGALP00010040928.1" } ] } }, { "isoform_ac": "A0A8V1ACH1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACH1/entry#A0A8V1ACH1-1", "sequence": { "sequence": "MEGPELPVQAEMVELVPNGKHAAALGTTTIPSLPGDRFDENQCGAEMEEFLPHGSEKKQTHFTDFEGKTSFGMSVFNLSNAIMGSGILGLAYAMANTGIILFLFLLTAVALLSSYSIHLLLKSSGIVGIRAYEQLGFRAFGTPGKLAAAIAITLQNIGAMSSYLYIVKSEVPLVIQTFLNLEEKTTDWYLNGNYLVILVSVTVILPLALMKQLGYLGYASGFSLSCMVFFLISVIYKKFQIPCPLPEQGGNITSGINVTLGSEHWDGPAAPLPPEVGACTPSFFTLNSQTAYTIPIMAFAFVCHPEVLPIYTELKNPSKKKMQCISNISITVMYLMYFLAALFGYLTFYGRVESELLHTYSRVDPFDVLILCVRVAVLTAVTLTVPIVLFPVRRAIQQMLFQGKNFSWIRHVAIAVILLTFINLLVIFAPSILGIFGLIGATSAPCLIFIFPAIFYIRIMPKDKEPLRSTPKILAACFALLGVLFMIMSLSFIITDWATGGGRSGGSH", "length": 508, "header": "tr|A0A8V1ACH1-1|A0A8V1ACH1_CHICK Isoform 1 of Solute carrier family 38 member 3 OS=Gallus gallus OX=9031 GN=SLC38A3 PE=4 SV=1 CANONICAL=A0A8V1ACH1-1" }, "locus": { "chromosome": "12", "start_pos": 3395443, "end_pos": 3391283, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066916.1", "url": "https://www.ensembl.org/id/ENSGALT00010066916.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040933.1", "url": "https://www.ensembl.org/id/ENSGALP00010040933.1" } ] } }, { "isoform_ac": "A0A8V1AH41-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACH1/entry#A0A8V1AH41-1", "sequence": { "sequence": "MSPTLEKGRVLPSNEASTAGLEPCSSHPEPDPTPCHATRSPAPAMEGPELPVQAEMVELVPNGKHAAALGTTTIPSLPGDRFDENQCGAEMEEFLPHGSEKKQTHFTDFEGKTSFGMSVFNLSNAIMGSGILGLAYAMANTGIILFLFLLTAVALLSSYSIHLLLKSSGIVGIRAYEQLGFRAFGTPGKLAAAIAITLQNIGAMSSYLYIVKSEVPLVIQTFLNLEEKTTDWYLNGNYLVILVSVTVILPLALMKQLGYLGYASGFSLSCMVFFLISVIYKKFQIPCPLPEQGGNITSGINVTLGSEHWDGPAAPLPPEVGACTPSFFTLNSQTAYTIPIMAFAFVCHPEVLPIYTELKNPSKKKMQCISNISITVMYLMYFLAALFGYLTFYGRVESELLHTYSRVDPFDVLILCVRVAVLTAVTLTVPIVLFPVRRAIQQMLFQGKNFSWIRHVAIAVILLTFINLLVIFAPSILGIFGLIGATSAPCLIFIFPAIFYIRIMPKDKEPLRSTPKILAACFALLGVLFMIMSLSFIITDWATGGGRSGGSH", "length": 552, "header": "tr|A0A8V1AH41-1|A0A8V1ACH1_CHICK Computationally mapped isoform of Solute carrier family 38 member 3 OS=Gallus gallus OX=9031 GN=SLC38A3 PE=4 SV=1 CANONICAL=A0A8V1ACH1-1" }, "locus": { "chromosome": "12", "start_pos": 3398268, "end_pos": 3391283, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066911.1", "url": "https://www.ensembl.org/id/ENSGALT00010066911.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040930.1", "url": "https://www.ensembl.org/id/ENSGALP00010040930.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:429200", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:429200", "resource": "KEGG Pathway" }, { "id": "R-GGA-352230", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-352230", "resource": "Reactome", "description": "Amino acid transport across the plasma membrane" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3L7HP74-1", "protein_name": "Sodium-coupled neutral amino acid transporter 3", "gene_name": "Slc38a3", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEIPRQAEMVELVPNGKHLEGLLPVGVSTTNTQRAEDPQHCAEGKGFLQKSSSKEPHFTDFEGKTSFGMSVFNLSNAIMGSGILGLAYAMANTGIILFLFLLTAVALLSSYSIHLLLKSSGIVGIRAYEQLGYRAFGTPGKLAAALAITLQNIGAMSSYLYIIKSELPLVIQTFLNLEKPTSVWYMDGNYLVILVSVTIILPLALMRQLGYLGYSSGFSLSCMVFFLIAVIYKKFQVPCPLAHNLANATGNLSHMVVLEKAQLQDEPEAAAFCSPSYFTLNSQTAYTIPIMAFAFVCHPEVLPIYTELKDPSKKKMQHISNLSIAVMYVMYFLAALFGYLTFYDGVESELLHTYSKVDPFDVLILCVRVAVLIAVTLTVPIVLFPVRRAIQQMLFQNQEFSWLRHVIIATGLLTCINLLVIFAPNILGIFGIIGATSAPCLIFIFPAIFYFRIMPTEKEPARSIPKILALCFAAVGFLLMTMSLSFIIIDWVSGTSQHGGHH", "length": 502 }, "evidence": [ { "id": "A0A8V1ACH1", "url": "https://omabrowser.org/oma/group/A0A8V1ACH1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A4X1SL32-1", "protein_name": "Solute carrier family 38 member 3", "gene_name": "SLC38A3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEAPLQTEMVELVPNGKHLEGLLPVTAPMAGNQRVEGPGRSCVEGEGFLQKSPSKEPHFTDFEGKTSFGMSVFNLSNAIMGSGILGLAYAMANTGIILFLFLLTAVALLSSYSIHLLLKSSGIVGIRAYEQLGYRAFGTPGKLAAALAITLQNIGAMSSYLYIIKSELPLVIQTFLNLEEQTSDWYMNGNYLVILVSVIVILPLALMRQLGYLGYSSGFSLSCMVFFLIAVIYKKFHVPCPLAPSLANITGNFSLMEVVKEQAQLQVETEVTAFCTPNYFTLNTQTAYTIPIMAFAFVCHPEVLPIYTELKDPSKRKMQHISNLSIAVMYVMYFLAALFGYLTFYDGVESELLHTYSKVDPFDVLILCVRVAVLTAVTLTVPIVLFPVRRALQQMLFQDQEFSWLRHVLIAISLLTCINLLVIFAPNILGIFGVIGATSAPCLIFIFPAIFYFRIMPIEKEPAKSTPKILALCFAAVGLLLMTMSLSFIIIDWVSGTSQHGGSH", "length": 504 }, "evidence": [ { "id": "A0A8V1ACH1", "url": "https://omabrowser.org/oma/group/A0A8V1ACH1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1MXZ5-1", "protein_name": "Solute carrier family 38 member 3", "gene_name": "SLC38A3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MEAPLQTEMVELVPNGKHLEGLLPVATPTAGGQRVEGPGRSCVEGEGFLPKSPSKEPHFTDFEGKTSFGMSVFNLSNAIMGSGILGLAYAMANTGIILFLFLLTAVALLSSYSIHLLLKSSGIVGIRAYEQLGYRAFGTPGKLAAALAITLQNIGAMSSYLYIIKSELPLVIQTFLHLEDWTSDWYTNGNYLVILVSIVVILPLALMRQLGYLGYSSGFSLSCMMFFLIAVIYKKFHVPCPLSPNATNVTSNISLVEIDKDEAGLQAKTEAGAFCTPSYFTLNTQTAYTIPIMAFAFVCHPEVLPIYTELKDPSKRKMQRISNLSIAVMYVMYFLAALFGYLTFYDGVESELLHTYSKVDPFDVLILCVRVAVLTAVTLTVPIVLFPVRRALQQILFPNREFSWLRHVLIAVVLLTCINLLVIFAPNILGIFGVIGATSAPCLIFIFPAIFYFRIIPTEKEPARSTPKILALCFAALGILLMTMSLSFIIMDWVSGTSRHGGSH", "length": 504 }, "evidence": [ { "id": "A0A8V1ACH1", "url": "https://omabrowser.org/oma/group/A0A8V1ACH1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q99624-1", "protein_name": "Sodium-coupled neutral amino acid transporter 3", "gene_name": "SLC38A3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEAPLQTEMVELVPNGKHSEGLLPVITPMAGNQRVEDPARSCMEGKSFLQKSPSKEPHFTDFEGKTSFGMSVFNLSNAIMGSGILGLAYAMANTGIILFLFLLTAVALLSSYSIHLLLKSSGVVGIRAYEQLGYRAFGTPGKLAAALAITLQNIGAMSSYLYIIKSELPLVIQTFLNLEEKTSDWYMNGNYLVILVSVTIILPLALMRQLGYLGYSSGFSLSCMVFFLIAVIYKKFHVPCPLPPNFNNTTGNFSHVEIVKEKVQLQVEPEASAFCTPSYFTLNSQTAYTIPIMAFAFVCHPEVLPIYTELKDPSKKKMQHISNLSIAVMYIMYFLAALFGYLTFYNGVESELLHTYSKVDPFDVLILCVRVAVLTAVTLTVPIVLFPVRRAIQQMLFPNQEFSWLRHVLIAVGLLTCINLLVIFAPNILGIFGVIGATSAPFLIFIFPAIFYFRIMPTEKEPARSTPKILALCFAMLGFLLMTMSLSFIIIDWASGTSRHGGNH", "length": 504 }, "evidence": [ { "id": "A0A8V1ACH1", "url": "https://omabrowser.org/oma/group/A0A8V1ACH1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9DCP2-1", "protein_name": "Sodium-coupled neutral amino acid transporter 3", "gene_name": "Slc38a3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEIPRQTEMVELVPNGKHLEGLLPVGVPTTDTQRTEDTQHCGEGKGFLQKSPSKEPHFTDFEGKTSFGMSVFNLSNAIMGSGILGLAYAMANTGIILFLFLLTAVALLSSYSIHLLLKSSGIVGIRAYEQLGYRAFGTPGKLAAALAITLQNIGAMSSYLYIIKSELPLVIQTFLNLEKPASVWYMDGNYLVILVSVTIILPLALMRQLGYLGYSSGFSLSCMVFFLIAVIYKKFQVPCPLAHNLANATGNFSHMVVAEEKAQLQGEPDTAAEAFCTPSYFTLNSQTAYTIPIMAFAFVCHPEVLPIYTELKDPSKRKMQHISNLSIAVMYVMYFLAALFGYLTFYDGVESELLHTYSKVDPFDVLILCVRVAVLIAVTLTVPIVLFPVRRAIQQMLFQNQEFSWLRHVLIATGLLTCINLLVIFAPNILGIFGIIGATSAPCLIFIFPAIFYFRIMPTDKEPARSTPKILALCFAAVGFLLMTMSLSFIIIDWVSGTSQHGGNH", "length": 505 }, "evidence": [ { "id": "A0A8V1ACH1", "url": "https://omabrowser.org/oma/group/A0A8V1ACH1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9JHZ9-1", "protein_name": "Sodium-coupled neutral amino acid transporter 3", "gene_name": "Slc38a3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEIPRQTEMVELVPNGKHLEGLLPVGMPTADTQRAEDAQHCGEGKGFLQQSSSKEPHFTDFEGKTSFGMSVFNLSNAIMGSGILGLAYAMANTGIILFLFLLTAVALLSSYSIHLLLKSSGIVGIRAYEQLGYRAFGTPGKLAAALAITLQNIGAMSSYLYIIKSELPLVIQTFLNLEKPTPVWYMDGNYLVILVSVIIILPLALMRQLGYLGYSSGFSLSCMVFFLIAVIYKKFQVPCPLAHNLVNATGNFSHMVVVEEKSQLQSEPDTAEAFCTPSYFTLNSQTAYTIPIMAFAFVCHPEVLPIYTELKDPSKRKMQHISNLSIAVMYVMYFLAALFGYLTFYDGVESELLHTYSKVDPFDVLILCVRVAVLIAVTLTVPIVLFPVRRAIQQMLFQNQEFSWLRHVLIATGLLTCINLLVIFAPNILGIFGIIGATSAPCLIFIFPAIFYFRIMPTEKEPVRSTPKILALCFAAVGFLLMTMSLSFIITDWVSGTSQHGGNH", "length": 504 }, "evidence": [ { "id": "A0A8V1ACH1", "url": "https://omabrowser.org/oma/group/A0A8V1ACH1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "L-alanine transmembrane transporter activity", "id": "GO:0015180", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015180", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACH1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACH1" } ], "pmid": "" }, { "name": "L-glutamine transmembrane transporter activity", "id": "GO:0015186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015186", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACH1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACH1" } ], "pmid": "" }, { "name": "L-histidine transmembrane transporter activity", "id": "GO:0005290", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005290", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACH1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACH1" } ], "pmid": "" }, { "name": "L-asparagine transmembrane transporter activity", "id": "GO:0015182", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015182", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACH1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACH1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACH1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACH1" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACH1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACH1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "glutamine transport", "id": "GO:0006868", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006868", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACH1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACH1" } ], "pmid": "" }, { "name": "amino acid transmembrane transport", "id": "GO:0003333", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003333", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACH1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACH1" } ], "pmid": "" }, { "name": "asparagine transport", "id": "GO:0006867", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006867", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACH1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACH1" } ], "pmid": "" }, { "name": "histidine transport", "id": "GO:0015817", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015817", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACH1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACH1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 251, "end_pos": 253, "annotation": "n_glycosylation_sequon" }, { "start_pos": 257, "end_pos": 259, "annotation": "n_glycosylation_sequon" }, { "start_pos": 327, "end_pos": 329, "annotation": "n_glycosylation_sequon" }, { "start_pos": 405, "end_pos": 407, "annotation": "n_glycosylation_sequon" }, { "start_pos": 77, "end_pos": 79, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1ACH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACH1" }, { "id": "PF01490", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01490" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Amino acid transporter transmembrane", "eco_id": "ECO_0000259", "start_pos": 68, "end_pos": 494, "start_aa": "Lys", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 251, "end_pos": 253 }, { "start_pos": 257, "end_pos": 259 }, { "start_pos": 327, "end_pos": 329 }, { "start_pos": 405, "end_pos": 407 }, { "start_pos": 77, "end_pos": 79 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1ACK8-1", "uniprot_ac": "A0A8V1ACK8", "uniprot_id": "A0A8V1ACK8_CHICK", "mass": { "chemical_mass": 36581.0, "monoisotopic_mass": 36581.0 }, "refseq": { "ac": "XP_040505977", "name": "cytosolic arginine sensor for mTORC1 subunit 2 isoform X7", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040505977" }, "gene_names": [ { "name": "GATSL2", "type": "recommended", "evidence": [ { "id": "A0A8V1ACK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK8" } ] }, { "name": "CASTOR2", "type": "synonym", "evidence": [ { "id": "XP_040505977", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040505977" } ] }, { "name": "GATSL1", "type": "synonym", "evidence": [ { "id": "XP_040505977", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040505977" } ] }, { "name": "GATSL2", "type": "synonym", "evidence": [ { "id": "XP_040505977", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040505977" } ] }, { "name": "GATS", "type": "synonym", "evidence": [ { "id": "XP_040505977", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040505977" } ] } ], "protein_names": [ { "name": "GATS protein like 2", "type": "synonym", "evidence": [ { "id": "A0A8V1ACK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK8/entry#names_and_taxonomy" } ] }, { "name": "cytosolic arginine sensor for mTORC1 subunit 2 isoform X7", "type": "synonym", "evidence": [ { "id": "XP_040505977", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040505977" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052550.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040505977", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040505977" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACK8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "GATSL2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK8", "locus": { "chromosome": "19", "start_pos": 3118370, "end_pos": 3027752, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029373", "url": "https://www.ensembl.org/id/ENSGALG00010029373" } ] } } ], "crossref": [ { "id": "A0A8V1ACK8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1ACK8", "database": "AlphaFoldDB", "categories": [] }, { "id": "417483", "url": "https://www.ncbi.nlm.nih.gov/gene/417483", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026249", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026249", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027795", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027795", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040778", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040778", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045865", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045865", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049479", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049479", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ACK8", "url": "https://www.orthodb.org/?gene=A0A8V1ACK8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AHW4", "url": "https://www.orthodb.org/?gene=A0A8V1AHW4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AJV6", "url": "https://www.orthodb.org/?gene=A0A8V1AJV6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ALW5", "url": "https://www.orthodb.org/?gene=A0A8V1ALW5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ALW9", "url": "https://www.orthodb.org/?gene=A0A8V1ALW9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ANF9", "url": "https://www.orthodb.org/?gene=A0A8V1ANF9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31131", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31131", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31131:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31131:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13840", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13840", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18700", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18700", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21389", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21389", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-9639288", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9639288", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_040505977", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040505977", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1ACK8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ACK8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHW4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHW4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHW4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHW4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJV6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJV6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJV6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJV6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALW5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALW5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALW5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALW5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALW9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALW9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALW9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALW9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ANF9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANF9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ANF9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANF9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MELHILEHRLRVASIAKESIQLFTYGLIKLAFLSSKTRCKFFSLTETPEDYTIIVDEEGFLELPSSEHLSVADATWLALNVVSGGGGFSGSQPIGVTKIAKSVIAPLADQNISVFMLSTYQTDFILVRERDLPFVMHTLAAEFTILRVVNGETVAADDLGITNGFVKPKLVQRPVIHPLSSPSNMFCVTSLDPDTLPTVATLLMDVMFYSNGVKDSVVGNEDSGHIRFFSFSLIEGYISLVMDVQTQQRFPNNLLFTSASGELWKMVRIGGQPLGFDECGIVAQISEPLAAADIPAYYISTFKFDHALLQECSGSHSLSGRHCQDGNLQLSMDG", "length": 334, "header": "tr|A0A8V1ACK8-1|A0A8V1ACK8_CHICK Isoform 1 of GATS protein like 2 OS=Gallus gallus OX=9031 GN=GATSL2 PE=3 SV=1 CANONICAL=A0A8V1ACK8-1" }, "isoforms": [ { "isoform_ac": "A0A8V1ACK8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK8/entry#A0A8V1ACK8-1", "sequence": { "sequence": "MELHILEHRLRVASIAKESIQLFTYGLIKLAFLSSKTRCKFFSLTETPEDYTIIVDEEGFLELPSSEHLSVADATWLALNVVSGGGGFSGSQPIGVTKIAKSVIAPLADQNISVFMLSTYQTDFILVRERDLPFVMHTLAAEFTILRVVNGETVAADDLGITNGFVKPKLVQRPVIHPLSSPSNMFCVTSLDPDTLPTVATLLMDVMFYSNGVKDSVVGNEDSGHIRFFSFSLIEGYISLVMDVQTQQRFPNNLLFTSASGELWKMVRIGGQPLGFDECGIVAQISEPLAAADIPAYYISTFKFDHALLQECSGSHSLSGRHCQDGNLQLSMDG", "length": 334, "header": "tr|A0A8V1ACK8-1|A0A8V1ACK8_CHICK Isoform 1 of GATS protein like 2 OS=Gallus gallus OX=9031 GN=GATSL2 PE=3 SV=1 CANONICAL=A0A8V1ACK8-1" }, "locus": { "chromosome": "19", "start_pos": 3115510, "end_pos": 3028079, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071039.1", "url": "https://www.ensembl.org/id/ENSGALT00010071039.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043730.1", "url": "https://www.ensembl.org/id/ENSGALP00010043730.1" } ] } }, { "isoform_ac": "A0A8V1AHW4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK8/entry#A0A8V1AHW4-1", "sequence": { "sequence": "MELHILEHRLRVASIAKESIQLFTYGLIKLAFLSSKTRCKFFSLTETPEDYTIIVDEEGFLELPSSEHLSVADATWLALNVVSGGGGFSGSQPIGVTKIAKSVIAPLADQNISVFMLSTYQTDFILVRERDLPFVMHTLAAEFTILRVVNGETVAADDLGITNGFVKPKLVQRPVIHPLSSPSNMFCVTSLDPDTLPTVATLLMDVMFYSNGVKDSVVGNEDSGHIRFFSFSLIEGYISLVMDVQTQQRFPNNLLFTSASGELWKMVRIGGQPLGFDECGIVAQISEPLAAADIPAYYISTFKFDHALVPEENINGVVNALQYFLKNLIPESDMKRDCGKLSRNSSK", "length": 347, "header": "tr|A0A8V1AHW4-1|A0A8V1ACK8_CHICK Computationally mapped isoform of GATS protein like 2 OS=Gallus gallus OX=9031 GN=GATSL2 PE=3 SV=1 CANONICAL=A0A8V1ACK8-1" }, "locus": { "chromosome": "19", "start_pos": 3117366, "end_pos": 3028079, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071041.1", "url": "https://www.ensembl.org/id/ENSGALT00010071041.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043732.1", "url": "https://www.ensembl.org/id/ENSGALP00010043732.1" } ] } }, { "isoform_ac": "A0A8V1AJV6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK8/entry#A0A8V1AJV6-1", "sequence": { "sequence": "MELHILEHRLRVASIAKESIQLFTYGLIKLAFLSSKTRCKFFSLTETPEDYTIIVDEEGFLELPSSEHLSVADATWLALNVVSGGGGFSGSQPIGVTKIAKSVIAPLADQNISVFMLSTYQTDFILVRERDLPFVMHTLAAEFTILRVVNGETVAADDLGITNGFVKPKLVQRPVIHPLSSPSNMFCVTSLDPDTLPTVATLLMDVMFYSNGVKDSVVGNEDSGHIRFFSFSLIEGYISLVMDVQTQQRFPNNLLFTSASGELWKMVRIGGQPLGFDECGIVAQISEPLAAADIPAYYISTFKFDHALSALHCITSPFITARSLSNNPTCDLRKPRRAQGVFFALGFFQLVSWVFHSWRKPICSP", "length": 365, "header": "tr|A0A8V1AJV6-1|A0A8V1ACK8_CHICK Computationally mapped isoform of GATS protein like 2 OS=Gallus gallus OX=9031 GN=GATSL2 PE=3 SV=1 CANONICAL=A0A8V1ACK8-1" }, "locus": { "chromosome": "19", "start_pos": 3114625, "end_pos": 3028079, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071038.1", "url": "https://www.ensembl.org/id/ENSGALT00010071038.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043729.1", "url": "https://www.ensembl.org/id/ENSGALP00010043729.1" } ] } }, { "isoform_ac": "A0A8V1ALW5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK8/entry#A0A8V1ALW5-1", "sequence": { "sequence": "MEGQFSVCSAWAPVHHWCKFFSLTETPEDYTIIVDEEGFLELPSSEHLSVADATWLALNVVSGGGGFSGSQPIGVTKIAKSVIAPLADQNISVFMLSTYQTDFILVRERDLPFVMHTLAAEFTILRVVNGETVAADDLGITNGFVKPKLVQRPVIHPLSSPSNMFCVTSLDPDTLPTVATLLMDVMFYSNGVKDSVVGNEDSGHIRFFSFSLIEGYISLVMDVQTQQRFPNNLLFTSASGELWKMVRIGGQPLGFDECGIVAQISEPLAAADIPAYYISTFKFDHALVPEENINGVVNALQVSQAEKH", "length": 308, "header": "tr|A0A8V1ALW5-1|A0A8V1ACK8_CHICK Computationally mapped isoform of GATS protein like 2 OS=Gallus gallus OX=9031 GN=GATSL2 PE=3 SV=1 CANONICAL=A0A8V1ACK8-1" }, "locus": { "chromosome": "19", "start_pos": 3117208, "end_pos": 3039765, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071037.1", "url": "https://www.ensembl.org/id/ENSGALT00010071037.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043728.1", "url": "https://www.ensembl.org/id/ENSGALP00010043728.1" } ] } }, { "isoform_ac": "A0A8V1ALW9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK8/entry#A0A8V1ALW9-1", "sequence": { "sequence": "MELHILEHRLRVASIAKESIQLFTYGLIKLAFLSSKTRCKFFSLTETPEDYTIIVDEEGFLELPSSEHLSVADATWLALNVVSGGGGFSGSQPIGVTKIAKSVIAPLADQNISVFMLSTYQTDFILVRERDLPFVMHTLAAEFTILRVVNGETVAADDLGITNGFVKPKLVQRPVIHPLSSPSNMFCVTSLDPDTLPTVATLLMDVMFYSNGVKDSVVGNEDSGHIRFFSFSLIEGYISLVMDVQTQQRFPNNLLFTSASGELWKMVRIGGQPLGFDECGIVAQISEPLAAADIPAYYISTFKFDHALYFLKNLIPESDMKRDCGKLSRNSSK", "length": 333, "header": "tr|A0A8V1ALW9-1|A0A8V1ACK8_CHICK Computationally mapped isoform of GATS protein like 2 OS=Gallus gallus OX=9031 GN=GATSL2 PE=3 SV=1 CANONICAL=A0A8V1ACK8-1" }, "locus": { "chromosome": "19", "start_pos": 3117366, "end_pos": 3028079, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071042.1", "url": "https://www.ensembl.org/id/ENSGALT00010071042.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043733.1", "url": "https://www.ensembl.org/id/ENSGALP00010043733.1" } ] } }, { "isoform_ac": "A0A8V1ANF9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK8/entry#A0A8V1ANF9-1", "sequence": { "sequence": "MELHILEHRLRVASIAKESIQLFTYGLIKLAFLSSKTRGRKTPSLCPLPRVHLSAWAFPSQTTGIANASSGAFPRLGDFVALFRTRNGDVNSAARTLLVFPAWCKFFSLTETPEDYTIIVDEEGFLELPSSEHLSVADATWLALNVVSGGGGFSGSQPIGVTKIAKSVIAPLADQNISVFMLSTYQTDFILVRDIRGAGRVACQQMALNGTSATLGRTSCLRSSRSTKVRERDLPFVMHTLAAEFTILRVVNGETVAADDLGITNGFVKPKLVQRPVIHPLSSPSNMFCVTSLDPDTLPTVATLLMDVMFYSNGVKDSVVGNEDSGHIRFFSFSLIEGYISLVMDVQTQQRFPNNLLFTSASGELWKMVRIGGQPLGFDECGIVAQISEPLAAADIPAYYISTFKFDHALVPEENINGVVNALQVSQAEKH", "length": 431, "header": "tr|A0A8V1ANF9-1|A0A8V1ACK8_CHICK Computationally mapped isoform of GATS protein like 2 OS=Gallus gallus OX=9031 GN=GATSL2 PE=3 SV=1 CANONICAL=A0A8V1ACK8-1" }, "locus": { "chromosome": "19", "start_pos": 3117208, "end_pos": 3028079, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071040.1", "url": "https://www.ensembl.org/id/ENSGALT00010071040.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043731.1", "url": "https://www.ensembl.org/id/ENSGALP00010043731.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-9639288", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9639288", "resource": "Reactome", "description": "Amino acids regulate mTORC1" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACK8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK8" } ], "pmid": "" }, { "name": "GATOR2 complex", "id": "GO:0061700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061700", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACK8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACK8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "negative regulation of TORC1 signaling", "id": "GO:1904262", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904262", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACK8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK8" } ], "pmid": "" }, { "name": "cellular response to L-arginine", "id": "GO:1903577", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903577", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACK8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 111, "end_pos": 113, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1ACK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK8" }, { "id": "PF13840", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13840" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CASTOR ACT", "eco_id": "ECO_0000259", "start_pos": 73, "end_pos": 139, "start_aa": "Asp", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1ACK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK8" }, { "id": "PF18700", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18700" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CASTOR1 N-terminal", "eco_id": "ECO_0000259", "start_pos": 9, "end_pos": 69, "start_aa": "Arg", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1ACK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK8" }, { "id": "PF21389", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21389" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Cytosolic arginine sensor for mTORC1 subunit 1/2 ACT-like", "eco_id": "ECO_0000259", "start_pos": 177, "end_pos": 259, "start_aa": "His", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 111, "end_pos": 113 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1ACW4-1", "uniprot_ac": "A0A8V1ACW4", "uniprot_id": "A0A8V1ACW4_CHICK", "mass": { "chemical_mass": 40661.0, "monoisotopic_mass": 40661.0 }, "refseq": { "ac": "XP_024997573", "name": "UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like protein 1 isoform X5", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024997573" }, "gene_names": [ { "name": "B3GNTL1", "type": "recommended", "evidence": [ { "id": "A0A8V1ACW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACW4" } ] }, { "name": "B3GNTL1", "type": "synonym", "evidence": [ { "id": "XP_024997573", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024997573" } ] } ], "protein_names": [ { "name": "UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase like 1", "type": "synonym", "evidence": [ { "id": "A0A8V1ACW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACW4/entry#names_and_taxonomy" } ] }, { "name": "UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like protein 1 isoform X5", "type": "synonym", "evidence": [ { "id": "XP_024997573", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024997573" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052549.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_024997573.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_024997573", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024997573" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACW4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACW4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "B3GNTL1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACW4", "locus": { "chromosome": "18", "start_pos": 3859132, "end_pos": 3746964, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029413", "url": "https://www.ensembl.org/id/ENSGALG00010029413" } ] } } ], "crossref": [ { "id": "A0A8V1ACW4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1ACW4", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd06913", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06913", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "417333", "url": "https://www.ncbi.nlm.nih.gov/gene/417333", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001173", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001173", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029044", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029044", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ACV8", "url": "https://www.orthodb.org/?gene=A0A8V1ACV8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ACW1", "url": "https://www.orthodb.org/?gene=A0A8V1ACW1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ACW4", "url": "https://www.orthodb.org/?gene=A0A8V1ACW4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AI69", "url": "https://www.orthodb.org/?gene=A0A8V1AI69", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AI74", "url": "https://www.orthodb.org/?gene=A0A8V1AI74", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AK48", "url": "https://www.orthodb.org/?gene=A0A8V1AK48", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AK53", "url": "https://www.orthodb.org/?gene=A0A8V1AK53", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AM42", "url": "https://www.orthodb.org/?gene=A0A8V1AM42", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ANN0", "url": "https://www.orthodb.org/?gene=A0A8V1ANN0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ANN3", "url": "https://www.orthodb.org/?gene=A0A8V1ANN3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22916", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22916", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22916:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22916:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00535", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00535", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-913709", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-913709", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_024997573", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024997573", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1ACV8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACV8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ACV8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACV8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ACW1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACW1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ACW1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACW1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ACW4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACW4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ACW4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACW4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AI69", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI69", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AI69-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI69-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AI74", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI74", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AI74-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI74-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AK48", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK48", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AK48-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK48-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AK53", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK53", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AK53-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK53-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AM42", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM42", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AM42-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM42-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ANN0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANN0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ANN0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANN0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ANN3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANN3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ANN3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANN3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAEAERAAGSPPGAVQSVIVPVHNSECWLDECLKSVWEQDFKQTMELSIFNDASKDGSAEIIAKWKVKLEDAGVPVVVGSNDSAQPRGVGFAKNQAIIQSSGTYLCFLDSDDVMMPQRVRLQHEAAIQHPNSIIGCQVRREPPESTARYTRWINNLTEEQLLTQVFTSHGPTVIMPTWFCSREWFYHVGKFDEGGKGVPEDLLFFYKHLQKGGGVLRVNRCLLLYRYHPQAATHSVHEETIWNHRVKFLEDRVLSTWTSFTIWNAGKQGKKLYRSLSPANRKKVTAFCDVDEKKIAKGFYTFEESEERPKPKIPICHFREATPPFIICVKQDLTGGAFETNLSMLNLKEGRDYYHFN", "length": 357, "header": "tr|A0A8V1ACW4-1|A0A8V1ACW4_CHICK Isoform 1 of UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase like 1 OS=Gallus gallus OX=9031 GN=B3GNTL1 PE=4 SV=1 CANONICAL=A0A8V1ACW4-1" }, "isoforms": [ { "isoform_ac": "A0A8V1ACV8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACW4/entry#A0A8V1ACV8-1", "sequence": { "sequence": "MLALKPTEHITFNRMVCCVHWTARLPGARNRGVPEDLLFFYKHLQKGGGVLRVNRCLLLYRYHPQAATHSVHEETIWNHRVKFLEDRVLSTWTSFTIWNAGKQGKKLYRSLSPANRKKVTAFCDVDEKKIAKGFYTFEESEERPKPKIPICHFREATPPFIICVKQDLTGGAFETNLSMLNLKEGRDYYHFN", "length": 192, "header": "tr|A0A8V1ACV8-1|A0A8V1ACV8_CHICK Computationally mapped isoform of UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase like 1 OS=Gallus gallus OX=9031 GN=B3GNTL1 PE=4 SV=1 CANONICAL=A0A8V1ACW4-1" }, "locus": { "chromosome": "18", "start_pos": 3856432, "end_pos": 3793534, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071147.1", "url": "https://www.ensembl.org/id/ENSGALT00010071147.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043838.1", "url": "https://www.ensembl.org/id/ENSGALP00010043838.1" } ] } }, { "isoform_ac": "A0A8V1ACW1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACW4/entry#A0A8V1ACW1-1", "sequence": { "sequence": "MAEAERAAGSPPGAVQVSVIVPVHNSECWLDECLKSVWEQDFKQTMELSIFNDASKDGSAEIIAKWKVKLEDAGVPVVVGSNDSAQPRGVGFAKNQAIIQSSGTYLCFLDSDDVMMPQRVRLQHEAAIQHPNSIIGCQVRREPPESTARYTRWINNLTEEQLLTQVFTSHGPTVIMPTWFCSREWFYHVGKFDEGGKGVPEDLLFFYKHLQKGGGVLRVNRCLLLYRYHPQAATHSVHEETIWNHRVKFLEDRVLSTWTSFTIWNAGKQGKKLYRSLSPANRKKVTAFCDVDEKKIAKGFYTFEESEERPKPKIPICHFREATPPFIICVKQFWIR", "length": 336, "header": "tr|A0A8V1ACW1-1|A0A8V1ACW1_CHICK Computationally mapped isoform of UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase like 1 OS=Gallus gallus OX=9031 GN=B3GNTL1 PE=4 SV=1 CANONICAL=A0A8V1ACW4-1" }, "locus": { "chromosome": "18", "start_pos": 3855140, "end_pos": 3747121, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071152.1", "url": "https://www.ensembl.org/id/ENSGALT00010071152.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043843.1", "url": "https://www.ensembl.org/id/ENSGALP00010043843.1" } ] } }, { "isoform_ac": "A0A8V1ACW4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACW4/entry#A0A8V1ACW4-1", "sequence": { "sequence": "MAEAERAAGSPPGAVQSVIVPVHNSECWLDECLKSVWEQDFKQTMELSIFNDASKDGSAEIIAKWKVKLEDAGVPVVVGSNDSAQPRGVGFAKNQAIIQSSGTYLCFLDSDDVMMPQRVRLQHEAAIQHPNSIIGCQVRREPPESTARYTRWINNLTEEQLLTQVFTSHGPTVIMPTWFCSREWFYHVGKFDEGGKGVPEDLLFFYKHLQKGGGVLRVNRCLLLYRYHPQAATHSVHEETIWNHRVKFLEDRVLSTWTSFTIWNAGKQGKKLYRSLSPANRKKVTAFCDVDEKKIAKGFYTFEESEERPKPKIPICHFREATPPFIICVKQDLTGGAFETNLSMLNLKEGRDYYHFN", "length": 357, "header": "tr|A0A8V1ACW4-1|A0A8V1ACW4_CHICK Isoform 1 of UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase like 1 OS=Gallus gallus OX=9031 GN=B3GNTL1 PE=4 SV=1 CANONICAL=A0A8V1ACW4-1" }, "locus": { "chromosome": "18", "start_pos": 3856432, "end_pos": 3747121, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071157.1", "url": "https://www.ensembl.org/id/ENSGALT00010071157.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043848.1", "url": "https://www.ensembl.org/id/ENSGALP00010043848.1" } ] } }, { "isoform_ac": "A0A8V1AI69-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACW4/entry#A0A8V1AI69-1", "sequence": { "sequence": "MIIGCQVRREPPESTARYTRWINNLTEEQLLTQVFTSHGPTVIMPTWFCSREWFYHVGKFDEGGKGVPEDLLFFYKHLQKGGGVLRVNRCLLLYRYHPQAATHSVHEETIWNHRVKFLEDRVLSTWTSFTIWNAGKQGKKLYRSLSPANRKKVTAFCDVDEKKIAKGFYTFEESEERPKPKIPICHFREATPPFIICVKQDLTGGAFETNLSMLNLKEGRDYYHFN", "length": 226, "header": "tr|A0A8V1AI69-1|A0A8V1ACW4_CHICK Computationally mapped isoform of UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase like 1 OS=Gallus gallus OX=9031 GN=B3GNTL1 PE=4 SV=1 CANONICAL=A0A8V1ACW4-1" }, "locus": { "chromosome": "18", "start_pos": 3856432, "end_pos": 3778359, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071149.1", "url": "https://www.ensembl.org/id/ENSGALT00010071149.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043840.1", "url": "https://www.ensembl.org/id/ENSGALP00010043840.1" } ] } }, { "isoform_ac": "A0A8V1AI74-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACW4/entry#A0A8V1AI74-1", "sequence": { "sequence": "MAEAERAAGSPPGAVQNGSAGGNLKDHPVPPRAVCCLRPIRARDGAPQLWAVPGPHRLWSVIVPVHNSECWLDECLKSVWEQDFKQTMELSIFNDASKDGSAEIIAKWKVKLEDAGVPVVVGSNDSAQPRGVGFAKNQAIIQSSGTYLCFLDSDDVMMPQRVRLQHEAAIQHPNSIIGCQVRREPPESTARYTRWINNLTEEQLLTQVFTSHGPTVIMPTWFCSREWFYHVGKFDEGGKGVPEDLLFFYKHLQKGGGVLRVNRCLLLYRYHPQAATHSVHEETIWNHRVKFLEDRVLSTWTSFTIWNAGKQGKKLYRSLSPANRKKVTAFCDVDEKKIAKGFYTFEESEERPKPKIPICHFREATPPFIICVKQDLTGGAFETNLSMLNLKEGRDYYHFN", "length": 400, "header": "tr|A0A8V1AI74-1|A0A8V1ACW4_CHICK Computationally mapped isoform of UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase like 1 OS=Gallus gallus OX=9031 GN=B3GNTL1 PE=4 SV=1 CANONICAL=A0A8V1ACW4-1" }, "locus": { "chromosome": "18", "start_pos": 3856432, "end_pos": 3747121, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071154.1", "url": "https://www.ensembl.org/id/ENSGALT00010071154.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043845.1", "url": "https://www.ensembl.org/id/ENSGALP00010043845.1" } ] } }, { "isoform_ac": "A0A8V1AK48-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACW4/entry#A0A8V1AK48-1", "sequence": { "sequence": "MNKSVIVPVHNSECWLDECLKSVWEQDFKQTMELSIFNDASKDGSAEIIAKWKVKLEDAGVPVVVGSNDSAQPRGVGFAKNQAIIQSSGTYLCFLDSDDVMMPQRVRLQHEAAIQHPNSIIGCQVRREPPESTARYTRWINNLTEEQLLTQVFTSHGPTVIMPTWFCSREWFYHVGKFDEGGKGVPEDLLFFYKHLQKGGGVLRVNRCLLLYRYHPQAATHSVHEETIWNHRVKFLEDRVLSTWTSFTIWNAGKQGKKLYRSLSPANRKKVTAFCDVDEKKIAKGFYTFEESEERPKPKIPICHFREATPPFIICVKQDLTGGAFETNLSMLNLKEGRDYYHFN", "length": 344, "header": "tr|A0A8V1AK48-1|A0A8V1ACW4_CHICK Computationally mapped isoform of UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase like 1 OS=Gallus gallus OX=9031 GN=B3GNTL1 PE=4 SV=1 CANONICAL=A0A8V1ACW4-1" }, "locus": { "chromosome": "18", "start_pos": 3856432, "end_pos": 3749912, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071151.1", "url": "https://www.ensembl.org/id/ENSGALT00010071151.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043842.1", "url": "https://www.ensembl.org/id/ENSGALP00010043842.1" } ] } }, { "isoform_ac": "A0A8V1AK53-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACW4/entry#A0A8V1AK53-1", "sequence": { "sequence": "MAEAERAAGSPPGAVQVSVIVPVHNSECWLDECLKSVWEQDFKQTMELSIFNDASKDGSAEIIAKWKVKLEDAGVPVVVGSNDSAQPRGVGFAKNQAIIQSSGTYLCFLDSDDVMMPQRVRLQHEAAIQHPNSIIGCQVRREPPESTARYTRWINNLTEEQLLTQGVPEDLLFFYKHLQKGGGVLRVNRCLLLYRYHPQAATHSVHEETIWNHRVKFLEDRVLSTWTSFTIWNAGKQGKKLYRSLSPANRKKVTAFCDVDEKKIAKGFYTFEESEERPKPKIPICHFREATPPFIICVKQDLTGGAFETNLSMLNLKEGRDYYHFN", "length": 326, "header": "tr|A0A8V1AK53-1|A0A8V1ACW4_CHICK Computationally mapped isoform of UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase like 1 OS=Gallus gallus OX=9031 GN=B3GNTL1 PE=4 SV=1 CANONICAL=A0A8V1ACW4-1" }, "locus": { "chromosome": "18", "start_pos": 3856432, "end_pos": 3747121, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071156.1", "url": "https://www.ensembl.org/id/ENSGALT00010071156.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043847.1", "url": "https://www.ensembl.org/id/ENSGALP00010043847.1" } ] } }, { "isoform_ac": "A0A8V1AM42-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACW4/entry#A0A8V1AM42-1", "sequence": { "sequence": "MAEAERAAGSPPGAVQSVIVPVHNSECWLDECLKSVWEQDFKQTMELSIFNDASKDGSAEIIAKWKVKLEDAGVPVVVGSNDSAQPRGVGFAKNQAIIQSSGTYLCFLDSDDVMMPQRVRLQHEAAIQHPNSIIGCQVRREPPESTARYTRWINNLTEEQLLTQVFTSHGPTVIMPTWFCSREWFYHVGKFDEGGKGVPEDLLFFYKHLQKGGGVLRVNRCLLLYRYHPQAATHSVHEETIWNHRVKFLEDRVLSTWTSFTIWNAGKQGKKLYRSLSPANRKKVTAFCDVDEKKIAKGFYTFEESEILRLCLQHSHSPTSFINKIILQAVMNP", "length": 333, "header": "tr|A0A8V1AM42-1|A0A8V1ACW4_CHICK Computationally mapped isoform of UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase like 1 OS=Gallus gallus OX=9031 GN=B3GNTL1 PE=4 SV=1 CANONICAL=A0A8V1ACW4-1" }, "locus": { "chromosome": "18", "start_pos": 3850341, "end_pos": 3747121, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071150.1", "url": "https://www.ensembl.org/id/ENSGALT00010071150.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043841.1", "url": "https://www.ensembl.org/id/ENSGALP00010043841.1" } ] } }, { "isoform_ac": "A0A8V1ANN0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACW4/entry#A0A8V1ANN0-1", "sequence": { "sequence": "SEIQGVPEDLLFFYKHLQKGGGVLRVNRCLLLYRYHPQAATHSVHEETIWNHRVKFLEDRVLSTWTSFTIWNAGKQGKKLYRSLSPANRKKVTAFCDVDEKKIAKGFYTFEESEERPKPKIPICHFREATPPFIICVKQDLTGGAFETNLSMLNLKEGRDYYHFN", "length": 165, "header": "tr|A0A8V1ANN0-1|A0A8V1ACW4_CHICK Computationally mapped isoform of UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase like 1 OS=Gallus gallus OX=9031 GN=B3GNTL1 PE=4 SV=1 CANONICAL=A0A8V1ACW4-1" }, "locus": { "chromosome": "18", "start_pos": 3856432, "end_pos": 3781472, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071148.1", "url": "https://www.ensembl.org/id/ENSGALT00010071148.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043839.1", "url": "https://www.ensembl.org/id/ENSGALP00010043839.1" } ] } }, { "isoform_ac": "A0A8V1ANN3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACW4/entry#A0A8V1ANN3-1", "sequence": { "sequence": "MAEAERAAGSPPGAVQVSVIVPVHNSECWLDECLKSVWEQDFKQTMELSIFNDASKDGSAEIIAKWKVKLEDAGVPVVVGSNDSAQPRGVGFAKNQAIIQSSGTYLCFLDSDDVMMPQRVRLQHEAAIQHPNSIIGCQVRREPPESTARYTRWINNLTEEQLLTQVFTSHGPTVIMPTWFCSREWFYHVGKFDEGGKGVPEDLLFFYKHLQKGGGVLRVNRCLLLYRYHPQAATHSVHEETIWNHRVKFLEDRVLSTWTSFTIWNAGKQGKKLYRSLSPANRKKERPKPKIPICHFREATPPFIICVKQDLTGGAFETNLSMLNLKEGRDYYHFN", "length": 335, "header": "tr|A0A8V1ANN3-1|A0A8V1ACW4_CHICK Computationally mapped isoform of UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase like 1 OS=Gallus gallus OX=9031 GN=B3GNTL1 PE=4 SV=1 CANONICAL=A0A8V1ACW4-1" }, "locus": { "chromosome": "18", "start_pos": 3856432, "end_pos": 3747121, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071153.1", "url": "https://www.ensembl.org/id/ENSGALT00010071153.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043844.1", "url": "https://www.ensembl.org/id/ENSGALP00010043844.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-913709", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-913709", "resource": "Reactome", "description": "O-linked glycosylation of mucins" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "glycosyltransferase activity", "id": "GO:0016757", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016757", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACW4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACW4" } ], "pmid": "" }, { "name": "tRNA-queuosine(34) galactosyltransferase activity", "id": "GO:0141125", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0141125", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACW4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACW4" } ], "pmid": "" }, { "name": "hexosyltransferase activity", "id": "GO:0016758", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016758", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACW4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACW4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACW4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACW4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "regulation of translation", "id": "GO:0006417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006417", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACW4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACW4" } ], "pmid": "" }, { "name": "tRNA wobble guanine modification", "id": "GO:0002099", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002099", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACW4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACW4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 155, "end_pos": 157, "annotation": "n_glycosylation_sequon" }, { "start_pos": 341, "end_pos": 343, "annotation": "n_glycosylation_sequon" }, { "start_pos": 81, "end_pos": 83, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1ACW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACW4" }, { "id": "PF00535", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00535" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Glycosyltransferase 2-like", "eco_id": "ECO_0000259", "start_pos": 17, "end_pos": 188, "start_aa": "Ser", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 155, "end_pos": 157 }, { "start_pos": 341, "end_pos": 343 }, { "start_pos": 81, "end_pos": 83 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1ADD2-1", "uniprot_ac": "A0A8V1ADD2", "uniprot_id": "A0A8V1ADD2_CHICK", "mass": { "chemical_mass": 36513.0, "monoisotopic_mass": 36513.0 }, "refseq": {}, "gene_names": [ { "name": "MSI2", "type": "recommended", "evidence": [ { "id": "A0A8V1ADD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADD2" } ] } ], "protein_names": [ { "name": "RNA-binding protein Musashi homolog 2", "type": "recommended", "evidence": [ { "id": "A0A8V1ADD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADD2/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "RNA binding protein that regulates the expression of target mRNAs at the translation level. May play a role in the proliferation and maintenance of stem cells in the central nervous system.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKK3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKK3#function" }, { "database": "UniProtKB", "id": "ARBA00058925", "url": "https://www.uniprot.org/uniprotkb/ARBA00058925#function" }, { "database": "UniProtKB", "id": "A0A8V1AMH5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMH5#function" }, { "database": "UniProtKB", "id": "A0A8V1AP10", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP10#function" }, { "database": "UniProtKB", "id": "A0A8V1ADD2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADD2#function" }, { "database": "UniProtKB", "id": "A0A8V1ADD6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADD6#function" }, { "database": "UniProtKB", "id": "A0A8V1AIS2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIS2#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADD2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADD2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MSI2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADD2", "locus": { "chromosome": "19", "start_pos": 9259497, "end_pos": 9444520, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029517", "url": "https://www.ensembl.org/id/ENSGALG00010029517" } ] } } ], "crossref": [ { "id": "A0A8V1ADD2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1ADD2", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd12323", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12323", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12760", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12760", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "417667", "url": "https://www.ncbi.nlm.nih.gov/gene/417667", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034126", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034126", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ADD2", "url": "https://www.orthodb.org/?gene=A0A8V1ADD2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ADD6", "url": "https://www.orthodb.org/?gene=A0A8V1ADD6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AIS2", "url": "https://www.orthodb.org/?gene=A0A8V1AIS2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AKK3", "url": "https://www.orthodb.org/?gene=A0A8V1AKK3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AMH0", "url": "https://www.orthodb.org/?gene=A0A8V1AMH0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AMH5", "url": "https://www.orthodb.org/?gene=A0A8V1AMH5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AP10", "url": "https://www.orthodb.org/?gene=A0A8V1AP10", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48032", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48032", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR48032:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48032:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00076", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00076", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-9013418", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013418", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1ADD2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADD2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ADD2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADD2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ADD6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADD6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ADD6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADD6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AIS2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIS2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AIS2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIS2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AKK3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKK3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AKK3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKK3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AMH0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMH0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AMH0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMH0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AMH5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMH5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AMH5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMH5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AP10", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP10", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AP10-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP10-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEADGSQATSGGPGEAQHDPGKMFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFGFVTFADPGSVDKVLAQPHHELDSKTIDPKVAFPRRAQPKMVTRTKKIFVGGLSANTVVEDVKQYFEQFGKVEDAMLMFDKTTNRHRGFGFVTFENEDVVEKVCEIHFHEINNKMVECKKAQPKEVMFPPGTRGRARGLPYTMDAFMLGMGMLGYPNFVATYGRGYPGFAPSYSYQFPGFPAAAYGPVAAAAVAAARGSGFVLRTNRPEGVSEAYFPASLTLGRAHLLSNTLLSALSGKAPTQPGPEASLGPTALGPSQTSTAQPARTPASATT", "length": 338, "header": "tr|A0A8V1ADD2-1|A0A8V1ADD2_CHICK Isoform 1 of RNA-binding protein Musashi homolog 2 OS=Gallus gallus OX=9031 GN=MSI2 PE=3 SV=1 CANONICAL=A0A8V1ADD2-1" }, "isoforms": [ { "isoform_ac": "A0A8V1ADD2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADD2/entry#A0A8V1ADD2-1", "sequence": { "sequence": "MEADGSQATSGGPGEAQHDPGKMFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFGFVTFADPGSVDKVLAQPHHELDSKTIDPKVAFPRRAQPKMVTRTKKIFVGGLSANTVVEDVKQYFEQFGKVEDAMLMFDKTTNRHRGFGFVTFENEDVVEKVCEIHFHEINNKMVECKKAQPKEVMFPPGTRGRARGLPYTMDAFMLGMGMLGYPNFVATYGRGYPGFAPSYSYQFPGFPAAAYGPVAAAAVAAARGSGFVLRTNRPEGVSEAYFPASLTLGRAHLLSNTLLSALSGKAPTQPGPEASLGPTALGPSQTSTAQPARTPASATT", "length": 338, "header": "tr|A0A8V1ADD2-1|A0A8V1ADD2_CHICK Isoform 1 of RNA-binding protein Musashi homolog 2 OS=Gallus gallus OX=9031 GN=MSI2 PE=3 SV=1 CANONICAL=A0A8V1ADD2-1" }, "locus": { "chromosome": "19", "start_pos": 9444205, "end_pos": 9264167, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071348.1", "url": "https://www.ensembl.org/id/ENSGALT00010071348.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044039.1", "url": "https://www.ensembl.org/id/ENSGALP00010044039.1" } ] } }, { "isoform_ac": "A0A8V1ADD6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADD2/entry#A0A8V1ADD6-1", "sequence": { "sequence": "MEADGSQATSGGPGEAQHDPGKMFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFGFVTFADPGSVDKVLAQPHHELDSKTIDPKVAFPRRAQPKMVTRTKKIFVGGLSANTVVEDVKQYFEQFGKVEDAMLMFDKTTNRHRGFGFVTFENEDVVEKVCEIHFHEINNKMVECKKAQPKEVMFPPGTRGRARGLPYTMDAFMLGMGMLGYPNFVATYGRGYPGFAPSYSYQFPGFPAAAYGPVAAAAVAAARGSGFVLRTNRPGSNPARPGGFPGANSPGPVADLYGTASQDSGVGNYISAASPQPGSGFSHGIASLSGCPGKTGRSF", "length": 337, "header": "tr|A0A8V1ADD6-1|A0A8V1ADD6_CHICK Computationally mapped isoform of RNA-binding protein Musashi homolog 2 OS=Gallus gallus OX=9031 GN=MSI2 PE=3 SV=1 CANONICAL=A0A8V1ADD2-1" }, "locus": { "chromosome": "19", "start_pos": 9444205, "end_pos": 9260716, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071353.1", "url": "https://www.ensembl.org/id/ENSGALT00010071353.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044044.1", "url": "https://www.ensembl.org/id/ENSGALP00010044044.1" } ] } }, { "isoform_ac": "A0A8V1AIS2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADD2/entry#A0A8V1AIS2-1", "sequence": { "sequence": "MADGGPALSPAPLSPPSKMFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFGFVTFADPGSVDKVLAQPHHELDSKTIDPKVAFPRRAQPKMVTRTKKIFVGGLSANTVVEDVKQYFEQFGKVEDAMLMFDKTTNRHRGFGFVTFENEDVVEKVCEIHFHEINNKMVECKKAQPKEVMFPPGTRGRARGLPYTMDAFMLGMGMLGYPNFVATYGRGYPGFAPSYSYQFPGFPAAAYGPVAAAAVAAARGSGRGARGRANPQSAGSVLNSYSAQPNFGAPASPAGSNPARPGGFPGANSPGPVADLYGTASQDSGVGNYISAASPQPGSGFSHGIAGPLIATAFTNGYH", "length": 357, "header": "tr|A0A8V1AIS2-1|A0A8V1ADD2_CHICK Computationally mapped isoform of RNA-binding protein Musashi homolog 2 OS=Gallus gallus OX=9031 GN=MSI2 PE=3 SV=1 CANONICAL=A0A8V1ADD2-1" }, "locus": { "chromosome": "19", "start_pos": 9444086, "end_pos": 9262371, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071350.1", "url": "https://www.ensembl.org/id/ENSGALT00010071350.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044041.1", "url": "https://www.ensembl.org/id/ENSGALP00010044041.1" } ] } }, { "isoform_ac": "A0A8V1AKK3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADD2/entry#A0A8V1AKK3-1", "sequence": { "sequence": "MEADGSQATSGGPGEAQHDPGKMFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFGFVTFADPGSVDKVLAQPHHELDSKTIDPKVAFPRRAQPKMVTRTKKIFVGGLSANTVVEDVKQYFEQFGKVEDAMLMFDKTTNRHRGFGFVTFENEDVVEKVCEIHFHEINNKMVECKKAQPKEVMFPPGTRGRARGLPYTMDAFMLGMGMLGYPNFVATYGRGYPGFAPSYSYQFPDYLPISQDIIFIN", "length": 255, "header": "tr|A0A8V1AKK3-1|A0A8V1ADD2_CHICK Computationally mapped isoform of RNA-binding protein Musashi homolog 2 OS=Gallus gallus OX=9031 GN=MSI2 PE=3 SV=1 CANONICAL=A0A8V1ADD2-1" }, "locus": { "chromosome": "19", "start_pos": 9444205, "end_pos": 9291102, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071347.1", "url": "https://www.ensembl.org/id/ENSGALT00010071347.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044038.1", "url": "https://www.ensembl.org/id/ENSGALP00010044038.1" } ] } }, { "isoform_ac": "A0A8V1AMH0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADD2/entry#A0A8V1AMH0-1", "sequence": { "sequence": "MEADGSQATSGGPGEAQHDPGKMFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFGFVTFADPGSVDKVLAQPHHELDSKTIDPKVAFPRRAQPKMVTRTKKIFVGGLSANTVVEDVKQYFEQFGKELSKPAFLISLGSAYDVLLT", "length": 155, "header": "tr|A0A8V1AMH0-1|A0A8V1ADD2_CHICK Computationally mapped isoform of RNA-binding protein Musashi homolog 2 OS=Gallus gallus OX=9031 GN=MSI2 PE=3 SV=1 CANONICAL=A0A8V1ADD2-1" }, "locus": { "chromosome": "19", "start_pos": 9444205, "end_pos": 9341422, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071346.1", "url": "https://www.ensembl.org/id/ENSGALT00010071346.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044037.1", "url": "https://www.ensembl.org/id/ENSGALP00010044037.1" } ] } }, { "isoform_ac": "A0A8V1AMH5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADD2/entry#A0A8V1AMH5-1", "sequence": { "sequence": "MEADGSQATSGGPGEAQHDPGKMFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFGFVTFADPGSVDKVLAQPHHELDSKTIDPKVAFPRRAQPKMVTRTKKIFVGGLSANTVVEDVKQYFEQFGKVEDAMLMFDKTTNRHRGFGFVTFENEDVVEKVCEIHFHEINNKMVECKKAQPKEVMFPPGTRGRARGLPYTMDAFMLGMGMLGYPNFVATYGRGYPGFAPSYSYQFPGFPAAAYGPVAAAAVAAARGSVLNSYSAQPNFGAPASPAGSNPARPGGFPGANSPGPVADLYGTASQDSGVGNYISAASPQPGSGFSHGIASLSGCPGKTGRSF", "length": 346, "header": "tr|A0A8V1AMH5-1|A0A8V1ADD2_CHICK Computationally mapped isoform of RNA-binding protein Musashi homolog 2 OS=Gallus gallus OX=9031 GN=MSI2 PE=3 SV=1 CANONICAL=A0A8V1ADD2-1" }, "locus": { "chromosome": "19", "start_pos": 9444205, "end_pos": 9260716, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071351.1", "url": "https://www.ensembl.org/id/ENSGALT00010071351.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044042.1", "url": "https://www.ensembl.org/id/ENSGALP00010044042.1" } ] } }, { "isoform_ac": "A0A8V1AP10-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADD2/entry#A0A8V1AP10-1", "sequence": { "sequence": "MEADGSQATSGGPGEAQHDPGKMFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFGFVTFADPGSVDKVLAQPHHELDSKTIDPKVAFPRRAQPKMVTRTKKIFVGGLSANTVVEDVKQYFEQFGKVEDAMLMFDKTTNRHRGFGFVTFENEDVVEKVCEIHFHEINNKMVECKKAQPKEVMFPPGTRGRARGLPYTMDAFMLGMGMLGYPNFVATYGRGYPGFAPSYSYQFPGFPAAAYGPVAAAAVAAARGSEGVSEAYFPASLTLGRAHLLSNTLLSALSGKAPTQPGPEASLGPTALGPSQTSTAQPARTPASATT", "length": 329, "header": "tr|A0A8V1AP10-1|A0A8V1ADD2_CHICK Computationally mapped isoform of RNA-binding protein Musashi homolog 2 OS=Gallus gallus OX=9031 GN=MSI2 PE=3 SV=1 CANONICAL=A0A8V1ADD2-1" }, "locus": { "chromosome": "19", "start_pos": 9444205, "end_pos": 9264167, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071349.1", "url": "https://www.ensembl.org/id/ENSGALT00010071349.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044040.1", "url": "https://www.ensembl.org/id/ENSGALP00010044040.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-9013418", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013418", "resource": "Reactome", "description": "RHOBTB2 GTPase cycle" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADD2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADD2" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADD2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADD2" } ], "pmid": "" }, { "name": "poly(U) RNA binding", "id": "GO:0008266", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008266", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADD2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADD2" } ], "pmid": "" }, { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADD2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADD2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADD2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADD2" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADD2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADD2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "regulation of translation", "id": "GO:0006417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006417", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADD2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADD2" } ], "pmid": "" }, { "name": "central nervous system development", "id": "GO:0007417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007417", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADD2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADD2" } ], "pmid": "" }, { "name": "stem cell development", "id": "GO:0048864", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048864", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADD2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADD2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1ADD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADD2" }, { "id": "PS50102", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50102" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RRM", "eco_id": "ECO_0000259", "start_pos": 21, "end_pos": 111, "start_aa": "Gly", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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"n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1ACU1-1", "uniprot_ac": "A0A8V1ACU1", "uniprot_id": "A0A8V1ACU1_CHICK", "mass": { "chemical_mass": 42486.0, "monoisotopic_mass": 42486.0 }, "refseq": {}, "gene_names": [ { "name": "POLDIP2", "type": "recommended", "evidence": [ { "id": "A0A8V1ACU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACU1" } ] } ], "protein_names": [ { "name": "Polymerase delta-interacting protein 2", "type": "recommended", "evidence": [ { "id": "A0A8V1ACU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACU1/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Involved in DNA damage tolerance by regulating translesion synthesis (TLS) of templates carrying DNA damage lesions such as 8oxoG and abasic sites. May act by stimulating activity of DNA polymerases involved in TLS, such as PRIMPOL and polymerase delta (POLD1).", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACU1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACU1#function" }, { "database": "UniProtKB", "id": "ARBA00056470", "url": "https://www.uniprot.org/uniprotkb/ARBA00056470#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACU1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACU1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "POLDIP2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACU1", "locus": { "chromosome": "19", "start_pos": 6111154, "end_pos": 6120512, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029405", "url": "https://www.ensembl.org/id/ENSGALG00010029405" } ] } } ], "crossref": [ { "id": "A0A8V1ACU1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1ACU1", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR007474", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007474", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011722", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011722", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036623", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036623", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036767", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036767", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ACU1", "url": "https://www.orthodb.org/?gene=A0A8V1ACU1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AK30", "url": "https://www.orthodb.org/?gene=A0A8V1AK30", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AM26", "url": "https://www.orthodb.org/?gene=A0A8V1AM26", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14289", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14289", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14289:SF16", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14289:SF16", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04379", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04379", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08755", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08755", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1ACU1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACU1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ACU1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACU1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AK30", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK30", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AK30-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK30-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AM26", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM26", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AM26-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM26-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSGGAARRYLAAALGRCRARGLPLWEPLWQPPPARVPRALSGGSVAALSLLPRRHLSSRNRLEGKVLETVGVFEAPKQHGKYETGQLFLHSVFGYRGIVLFPWQARLYDRDVASPVTEKSENAAGHGSKEVKGKTHTYYQVLIDARDCPHISQRSQTEAVTFLANHDDSRALYAIPDYVSHEDILPYSSTDQVPIQHELFERFLMYDQTKVPPFVARDTLCAWQEKNHPWLELSDVHRETTENIRVTVIPFYMGMREAQNSHVYWWRYCIRLENLDSEVVQLRERHWRIFSLSGTLETVRGRGVVGREPVLSKEQPAFQYSSHVSLQASSGHMWGTFRFERPDGSHFDVRIPPFSLESNKDEKTPPSGLHW", "length": 371, "header": "tr|A0A8V1ACU1-1|A0A8V1ACU1_CHICK Isoform 1 of Polymerase delta-interacting protein 2 OS=Gallus gallus OX=9031 GN=POLDIP2 PE=1 SV=1 CANONICAL=A0A8V1ACU1-1" }, "isoforms": [ { "isoform_ac": "A0A8V1ACU1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACU1/entry#A0A8V1ACU1-1", "sequence": { "sequence": "MSGGAARRYLAAALGRCRARGLPLWEPLWQPPPARVPRALSGGSVAALSLLPRRHLSSRNRLEGKVLETVGVFEAPKQHGKYETGQLFLHSVFGYRGIVLFPWQARLYDRDVASPVTEKSENAAGHGSKEVKGKTHTYYQVLIDARDCPHISQRSQTEAVTFLANHDDSRALYAIPDYVSHEDILPYSSTDQVPIQHELFERFLMYDQTKVPPFVARDTLCAWQEKNHPWLELSDVHRETTENIRVTVIPFYMGMREAQNSHVYWWRYCIRLENLDSEVVQLRERHWRIFSLSGTLETVRGRGVVGREPVLSKEQPAFQYSSHVSLQASSGHMWGTFRFERPDGSHFDVRIPPFSLESNKDEKTPPSGLHW", "length": 371, "header": "tr|A0A8V1ACU1-1|A0A8V1ACU1_CHICK Isoform 1 of Polymerase delta-interacting protein 2 OS=Gallus gallus OX=9031 GN=POLDIP2 PE=1 SV=1 CANONICAL=A0A8V1ACU1-1" }, "locus": { "chromosome": "19", "start_pos": 6120451, "end_pos": 6113342, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071127.1", "url": "https://www.ensembl.org/id/ENSGALT00010071127.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043818.1", "url": "https://www.ensembl.org/id/ENSGALP00010043818.1" } ] } }, { "isoform_ac": "A0A8V1AK30-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACU1/entry#A0A8V1AK30-1", "sequence": { "sequence": "MSGGAARRYLAAALGRCRARGLPLWEPLWQPPPARVPRALSGGSVAALSLLPRRHLSSRNRLEGKVLETVGVFEAPKQHGKYETGQLFLHSVFGYRGIVLFPWQARLYDRDVASPVTEKSENAAGHGSKEVKGKTHTYYQVLIDARDCPHISQRSQTEAVTFLANHDDSRALYAIPGLDYVSHEDILPYSSTDQVPIQHELFERFLMYDQTKVPPFVARDTLCAWQEKNHPWLELSDVHRETTENIRVTVIPFYMGMRWRYCIRLENLDSEVVQLRERHWRIFSLSGTLETVRGRGVVGREPVLSKEQPAFQYSSHVSLQASSGHMWGTFRFERPDGSHFDVRIPPFSLESNKDEKTPPSGLHW", "length": 364, "header": "tr|A0A8V1AK30-1|A0A8V1ACU1_CHICK Computationally mapped isoform of Polymerase delta-interacting protein 2 OS=Gallus gallus OX=9031 GN=POLDIP2 PE=1 SV=1 CANONICAL=A0A8V1ACU1-1" }, "locus": { "chromosome": "19", "start_pos": 6120451, "end_pos": 6113342, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071126.1", "url": "https://www.ensembl.org/id/ENSGALT00010071126.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043817.1", "url": "https://www.ensembl.org/id/ENSGALP00010043817.1" } ] } }, { "isoform_ac": "A0A8V1AM26-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACU1/entry#A0A8V1AM26-1", "sequence": { "sequence": "MSGGAARRYLAAALGRCRARGLPLWEPLWQPPPARVPRALSGGSVAALSLLPRRHLSSRNRLEGKVLETVGVFEAPKQHGKYETGQLFLHSVFGYRGIVLFPWQARLYDRDVASPVTEKSENAAGHGSKEVKGKTHTYYQVLIDARDCPHISQRSQTEAVTFLANHDDSRALYAIPGLDYVSHEDILPYSSTDQVPIQHELFERFLMYDQTKVPPFVARDTLCAWQEKNHPWLELSDVHRETTENIRVTVIPFYMGMREAQNSHVYWWRYCIRLENLDSEVVQLRERHWRIFSLSGTLETVRGRGVVGRPVLSKEQPAFQYSSHVSLQASSGHIHEAVLYDLLYSVSPSVLCARLHAGISLDSGDGMQGCSLFGGDCSFTGLGFCSCSTVLCSQTIGMWGYSQFRPAKTFSLTGIQVLSSVMAGGKALSPSCSAVLHG", "length": 438, "header": "tr|A0A8V1AM26-1|A0A8V1ACU1_CHICK Computationally mapped isoform of Polymerase delta-interacting protein 2 OS=Gallus gallus OX=9031 GN=POLDIP2 PE=1 SV=1 CANONICAL=A0A8V1ACU1-1" }, "locus": { "chromosome": "19", "start_pos": 6120451, "end_pos": 6114301, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071125.1", "url": "https://www.ensembl.org/id/ENSGALT00010071125.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043816.1", "url": "https://www.ensembl.org/id/ENSGALP00010043816.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACU1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACU1" } ], "pmid": "" }, { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACU1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACU1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACU1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACU1" } ], "pmid": "" }, { "name": "mitochondrial nucleoid", "id": "GO:0042645", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042645", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACU1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACU1" } ], "pmid": "" }, { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACU1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACU1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "error-free translesion synthesis", "id": "GO:0070987", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070987", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACU1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACU1" } ], "pmid": "" }, { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACU1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACU1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1ACU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACU1" }, { "id": "PS51087", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51087" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "ApaG", "eco_id": "ECO_0000259", "start_pos": 238, "end_pos": 363, "start_aa": "Arg", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1ADQ1-1", "uniprot_ac": "A0A8V1ADQ1", "uniprot_id": "A0A8V1ADQ1_CHICK", "mass": { "chemical_mass": 61313.0, "monoisotopic_mass": 61313.0 }, "refseq": {}, "gene_names": [ { "name": "CHN1", "type": "recommended", "evidence": [ { "id": "A0A8V1ADQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADQ1" } ] } ], "protein_names": [ { "name": "N-chimaerin", "type": "recommended", "evidence": [ { "id": "A0A8V1ADQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADQ1/entry#names_and_taxonomy" } ] }, { "name": "A-chimaerin", "type": "synonym", "evidence": [ { "id": "A0A8V1ADQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADQ1/entry#names_and_taxonomy" } ] }, { "name": "Alpha-chimerin", "type": "synonym", "evidence": [ { "id": "A0A8V1ADQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADQ1/entry#names_and_taxonomy" } ] }, { "name": "N-chimerin", "type": "synonym", "evidence": [ { "id": "A0A8V1ADQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADQ1/entry#names_and_taxonomy" } ] }, { "name": "Rho GTPase-activating protein 2", "type": "synonym", "evidence": [ { "id": "A0A8V1ADQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADQ1/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "GTPase-activating protein for p21-rac.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A195", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A195#function" }, { "database": "UniProtKB", "id": "PIRNR038015", "url": "https://www.uniprot.org/uniprotkb/PIRNR038015#function" }, { "database": "UniProtKB", "id": "R4GI01", "url": "https://www.uniprot.org/uniprotkb/R4GI01#function" }, { "database": "UniProtKB", "id": "F1P3G3", "url": "https://www.uniprot.org/uniprotkb/F1P3G3#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADQ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADQ1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CHN1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADQ1", "locus": { "chromosome": "7", "start_pos": 16420719, "end_pos": 16340800, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010026697", "url": "https://www.ensembl.org/id/ENSGALG00010026697" } ] } } ], "crossref": [ { "id": "A0A8V1ADQ1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1ADQ1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000009293", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000009293", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd04372", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04372", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd10352", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd10352", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd20856", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20856", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "429021", "url": "https://www.ncbi.nlm.nih.gov/gene/429021", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000198", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000198", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000980", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000980", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002219", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002219", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008936", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008936", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017356", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017356", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020454", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020454", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035840", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035840", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036860", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036860", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037860", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037860", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046349", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046349", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051854", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051854", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:429021", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:429021", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FIESAXV", "url": "https://omabrowser.org/oma/group/FIESAXV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A195", "url": "https://www.orthodb.org/?gene=A0A8V1A195", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ADQ1", "url": "https://www.orthodb.org/?gene=A0A8V1ADQ1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1P3G3", "url": "https://www.orthodb.org/?gene=F1P3G3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "R4GI01", "url": "https://www.orthodb.org/?gene=R4GI01", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46075", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46075", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46075:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46075:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00017", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00017", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00130", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00130", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00620", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00620", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-9013148", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013148", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9013149", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013149", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1A195", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A195", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A195-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A195-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ADQ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADQ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ADQ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADQ1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1P3G3", "url": "https://www.uniprot.org/uniprotkb/F1P3G3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1P3G3-1", "url": "https://www.uniprot.org/uniprotkb/F1P3G3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "R4GI01", "url": "https://www.uniprot.org/uniprotkb/R4GI01", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "R4GI01-1", "url": "https://www.uniprot.org/uniprotkb/R4GI01-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLVIPEAAWGKFPLQKSRSSTVPLVQELFGCSLHGAVLQWPAEPQLQPFKSRSRYSGTPGSQVLSAAAAMGKELPNYSVCRVDTDEYRPPVWKSYLYQLQQEAPHPRRITCTCEVENRPKYYGREFHGMISREEADQLLSVAEGSYLIRESQRQPGTYTLALRFGSQTRNFRLYYDGKHFVGEKRFESIHDLVTDGLITLYIETKAAEYIAKMTINPIYEHIGYTTLNREPAHKKHMPTLRDAHDGKDSTGEDEVAEKRLTSLVRRATLKENEHVPKYEKIHNFKVHTFRGPHWCEYCANFMWGLIAQGVKCADCGLNVHKQCSKMVPNDCKPDLKHVKKVYSCDLTTLVKAHFTKRPMVVDMCIREIESRGLNSEGLYRVSGFSDLIEDVKMAFDRDGEKADISVNMYEDINIITGALKLYFRDLPIPLITYDAYPKFIESAKTTDPDEQLEILHEALKLLPPAHCETLRYLMAHLKRVTLHEKENLMSAENLGIVFGPTLMRAPELDAMAALNDIRYQRLVVEMLIKNEDILF", "length": 535, "header": "tr|A0A8V1ADQ1-1|A0A8V1ADQ1_CHICK Isoform 1 of N-chimaerin OS=Gallus gallus OX=9031 GN=CHN1 PE=4 SV=1 CANONICAL=A0A8V1ADQ1-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A195-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADQ1/entry#A0A8V1A195-1", "sequence": { "sequence": "MDRICLASLHKRRQRIESPLDFAFLDLSSNKEKYTDEYRPPVWKSYLYQLQQEAPHPRRITCTCEVENRPKYYGREFHGMISREEADQLLSVAEGSYLIRESQRQPGTYTLALRFGSQTRNFRLYYDGKHFVGEKRFESIHDLVTDGLITLYIETKAAEYIAKMTINPIYEHIGYTTLNREPAHKKHMPTLRDAHDGKDSTGEDEVAEKRLTSLVRRATLKENEHVPKYEKIHNFKVHTFRGPHWCEYCANFMWGLIAQGVKCADCGLNVHKQCSKMVPNDCKPDLKHVKKVYSCDLTTLVKAHFTKRPMVVDMCIREIESRGLNSEGLYRVSGFSDLIEDVKMAFDRDGEKADISVNMYEDINIITGALKLYFRDLPIPLITYDAYPKFIESAKTTDPDEQLEILHEALKLLPPAHCETLRYLMAHLKRVTLHEKENLMSAENLGIVFGPTLMRAPELDAMAALNDIRYQRLVVEMLIKNEDILF", "length": 486, "header": "tr|A0A8V1A195-1|A0A8V1ADQ1_CHICK Computationally mapped isoform of N-chimaerin OS=Gallus gallus OX=9031 GN=CHN1 PE=4 SV=1 CANONICAL=A0A8V1ADQ1-1" }, "locus": { "chromosome": "7", "start_pos": 16419953, "end_pos": 16345869, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010064809.1", "url": "https://www.ensembl.org/id/ENSGALT00010064809.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039632.1", "url": "https://www.ensembl.org/id/ENSGALP00010039632.1" } ] } }, { "isoform_ac": "A0A8V1ADQ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADQ1/entry#A0A8V1ADQ1-1", "sequence": { "sequence": "MLVIPEAAWGKFPLQKSRSSTVPLVQELFGCSLHGAVLQWPAEPQLQPFKSRSRYSGTPGSQVLSAAAAMGKELPNYSVCRVDTDEYRPPVWKSYLYQLQQEAPHPRRITCTCEVENRPKYYGREFHGMISREEADQLLSVAEGSYLIRESQRQPGTYTLALRFGSQTRNFRLYYDGKHFVGEKRFESIHDLVTDGLITLYIETKAAEYIAKMTINPIYEHIGYTTLNREPAHKKHMPTLRDAHDGKDSTGEDEVAEKRLTSLVRRATLKENEHVPKYEKIHNFKVHTFRGPHWCEYCANFMWGLIAQGVKCADCGLNVHKQCSKMVPNDCKPDLKHVKKVYSCDLTTLVKAHFTKRPMVVDMCIREIESRGLNSEGLYRVSGFSDLIEDVKMAFDRDGEKADISVNMYEDINIITGALKLYFRDLPIPLITYDAYPKFIESAKTTDPDEQLEILHEALKLLPPAHCETLRYLMAHLKRVTLHEKENLMSAENLGIVFGPTLMRAPELDAMAALNDIRYQRLVVEMLIKNEDILF", "length": 535, "header": "tr|A0A8V1ADQ1-1|A0A8V1ADQ1_CHICK Isoform 1 of N-chimaerin OS=Gallus gallus OX=9031 GN=CHN1 PE=4 SV=1 CANONICAL=A0A8V1ADQ1-1" }, "locus": { "chromosome": "7", "start_pos": 16419953, "end_pos": 16346204, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010064801.1", "url": "https://www.ensembl.org/id/ENSGALT00010064801.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039628.1", "url": "https://www.ensembl.org/id/ENSGALP00010039628.1" } ] } }, { "isoform_ac": "F1P3G3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADQ1/entry#F1P3G3-1", "sequence": { "sequence": "MALTLFDTDEYRPPVWKSYLYQLQQEAPHPRRITCTCEVENRPKYYGREFHGMISREEADQLLSVAEGSYLIRESQRQPGTYTLALRFGSQTRNFRLYYDGKHFVGEKRFESIHDLVTDGLITLYIETKAAEYIAKMTINPIYEHIGYTTLNREPAHKKHMPTLRDAHDGKDSTGEDEVAEKRLTSLVRRATLKENEHVPKYEKIHNFKVHTFRGPHWCEYCANFMWGLIAQGVKCADCGLNVHKQCSKMVPNDCKPDLKHVKKVYSCDLTTLVKAHFTKRPMVVDMCIREIESRGLNSEGLYRVSGFSDLIEDVKMAFDRDGEKADISVNMYEDINIITGALKLYFRDLPIPLITYDAYPKFIESAKTTDPDEQLEILHEALKLLPPAHCETLRYLMAHLKRVTLHEKENLMSAENLGIVFGPTLMRAPELDAMAALNDIRYQRLVVEMLIKNEDILF", "length": 459, "header": "tr|F1P3G3-1|F1P3G3_CHICK Computationally mapped isoform of Chimaerin OS=Gallus gallus OX=9031 GN=CHN1 PE=4 SV=2 CANONICAL=A0A8V1ADQ1-1" }, "locus": { "chromosome": "7", "start_pos": 16419953, "end_pos": 16341040, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010064815.1", "url": "https://www.ensembl.org/id/ENSGALT00010064815.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039636.1", "url": "https://www.ensembl.org/id/ENSGALP00010039636.1" } ] } }, { "isoform_ac": "R4GI01-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADQ1/entry#R4GI01-1", "sequence": { "sequence": "MPPGASRATVILVSRGIAKKEDTDEYRPPVWKSYLYQLQQEAPHPRRITCTCEVENRPKYYGREFHGMISREEADQLLSVAEGSYLIRESQRQPGTYTLALRFGSQTRNFRLYYDGKHFVGEKRFESIHDLVTDGLITLYIETKAAEYIAKMTINPIYEHIGYTTLNREPAHKKHMPTLRDAHDGKDSTGEDEVAEKRLTSLVRRATLKENEHVPKYEKIHNFKVHTFRGPHWCEYCANFMWGLIAQGVKCADCGLNVHKQCSKMVPNDCKPDLKHVKKVYSCDLTTLVKAHFTKRPMVVDMCIREIESRGLNSEGLYRVSGFSDLIEDVKMAFDRDGEKADISVNMYEDINIITGALKLYFRDLPIPLITYDAYPKFIESAKTTDPDEQLEILHEALKLLPPAHCETLRYLMAHLKRVTLHEKENLMSAENLGIVFGPTLMRAPELDAMAALNDIRYQRLVVEMLIKNEDILF", "length": 474, "header": "tr|R4GI01-1|R4GI01_CHICK Computationally mapped isoform of Chimaerin OS=Gallus gallus OX=9031 GN=CHN1 PE=4 SV=3 CANONICAL=A0A8V1ADQ1-1" }, "locus": { "chromosome": "7", "start_pos": 16419953, "end_pos": 16347907, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010064793.1", "url": "https://www.ensembl.org/id/ENSGALT00010064793.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039625.1", "url": "https://www.ensembl.org/id/ENSGALP00010039625.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 58, "start_aa": "Thr", "end_pos": 58, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr58", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:429021", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:429021", "resource": "KEGG Pathway" }, { "id": "R-GGA-9013148", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013148", "resource": "Reactome", "description": "CDC42 GTPase cycle" }, { "id": "R-GGA-9013149", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013149", "resource": "Reactome", "description": "RAC1 GTPase cycle" } ], "orthologs": [ { "uniprot_canonical_ac": "P15882-1", "protein_name": "N-chimaerin", "gene_name": "CHN1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MALTLFDTDEYRPPVWKSYLYQLQQEAPHPRRITCTCEVENRPKYYGREFHGMISREAADQLLIVAEGSYLIRESQRQPGTYTLALRFGSQTRNFRLYYDGKHFVGEKRFESIHDLVTDGLITLYIETKAAEYIAKMTINPIYEHVGYTTLNREPAYKKHMPVLKETHDERDSTGQDGVSEKRLTSLVRRATLKENEQIPKYEKIHNFKVHTFRGPHWCEYCANFMWGLIAQGVKCADCGLNVHKQCSKMVPNDCKPDLKHVKKVYSCDLTTLVKAHTTKRPMVVDMCIREIESRGLNSEGLYRVSGFSDLIEDVKMAFDRDGEKADISVNMYEDINIITGALKLYFRDLPIPLITYDAYPKFIESAKIMDPDEQLETLHEALKLLPPAHCETLRYLMAHLKRVTLHEKENLMNAENLGIVFGPTLMRSPELDAMAALNDIRYQRLVVELLIKNEDILF", "length": 459 }, "evidence": [ { "id": "A0A8V1ADQ1", "url": "https://omabrowser.org/oma/group/A0A8V1ADQ1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P30337-1", "protein_name": "N-chimaerin", "gene_name": "Chn1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPSKESWSGRKTNRATVHKSKQEGRQQDLLIAALGMKLGSQKSSVTIWQPLKLFAYSQLTSLVRRATLKENEQIPKYEKVHNFKVHTFRGPHWCEYCANFMWGLIAQGVKCADCGLNVHKQCSKMVPNDCKPDLKHVKKVYSCDLTTLVKAHITKRPMVVDMCIREIESRGLNSEGLYRVSGFSDLIEDVKMAFDRDGEKADISVNMYEDINIITGALKLYFRDLPIPLITYDAYPKFIESAKIVDPDEQLETLHEALRSLPPAHCETLRYLMAHLKRVTLHEKENLMSAENLGIVFGPTLMRSPELDPMAALNDIRYQRLVVELLIKNEDILF", "length": 334 }, "evidence": [ { "id": "A0A8V1ADQ1", "url": "https://omabrowser.org/oma/group/A0A8V1ADQ1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q91V57-1", "protein_name": "N-chimaerin", "gene_name": "Chn1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALTLFDTDEYRPPVWKSYLYQLQQEAPHPRRVTCTCEVENRPKYYGREYHGMISREETDQLLSVAEGSYLIRESQRQPGTYTLALRFGSQTRNFRLYYDGKHFVGEKRFESIHDLVTDGLITLYIETKAAEYIAKMTINPIYEHIGYTTLNREPAYKQHMAVLKETHDEKEATGQDGVSEKRLTSLVRRATLKENEQIPKYEKVHNFKVHTFRGPHWCEYCANFMWGLIAQGVKCADCGLNVHKQCSKMVPNDCKPDLKHVKKVYSCDLTTLVKAHITKRPMVVDMCIREIESRGLNSEGLYRVSGFSDLIEDVKMAFDRDGEKADISVNMYEDINIITGALKLYFRDLPIPLITYDAYPKFIESAKIMDPDEQLETLHEALRSLPPAHCETLRYLMAHLKRVTLHEKENLMSAENLGIVFGPTLMRSPELDPMAALNDIRYQRLVVELLIKNEDILF", "length": 459 }, "evidence": [ { "id": "A0A8V1ADQ1", "url": "https://omabrowser.org/oma/group/A0A8V1ADQ1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADQ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADQ1" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADQ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADQ1" } ], "pmid": "" }, { "name": "ephrin receptor binding", "id": "GO:0046875", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046875", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADQ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADQ1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADQ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADQ1" } ], "pmid": "" }, { "name": "nervous system development", "id": "GO:0007399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007399", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADQ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADQ1" } ], "pmid": "" }, { "name": "regulation of small GTPase mediated signal transduction", "id": "GO:0051056", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051056", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADQ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADQ1" } ], "pmid": "" }, { "name": "regulation of axonogenesis", "id": "GO:0050770", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050770", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADQ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADQ1" } ], "pmid": "" }, { "name": "ephrin receptor signaling pathway", "id": "GO:0048013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048013", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADQ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADQ1" } ], "pmid": "" }, { "name": "motor neuron axon guidance", "id": "GO:0008045", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008045", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADQ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADQ1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 76, "end_pos": 78, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1ADQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADQ1" }, { "id": "PS50081", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50081" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Phorbol-ester/DAG-type", "eco_id": "ECO_0000259", "start_pos": 281, "end_pos": 331, "start_aa": "Ile", "end_aa": "Cys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1ADQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADQ1" }, { "id": "PS50238", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50238" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Rho-GAP", "eco_id": "ECO_0000259", "start_pos": 344, "end_pos": 535, "start_aa": "Cys", "end_aa": "Phe", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1ADQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADQ1" }, { "id": "PS50001", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50001" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SH2", "eco_id": "ECO_0000259", "start_pos": 125, "end_pos": 193, "start_aa": "Glu", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 58 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 76, "end_pos": 78 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AE21-1", "uniprot_ac": "A0A8V1AE21", "uniprot_id": "A0A8V1AE21_CHICK", "mass": { "chemical_mass": 74431.0, "monoisotopic_mass": 74431.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Cadherin domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8V1AE21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE21/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AE21", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE21" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE21", "locus": {} } ], "crossref": [ { "id": "A0A8V1AE21", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AE21", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd11304", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11304", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR002126", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002126", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015919", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015919", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "LVHNDLM", "url": "https://omabrowser.org/oma/group/LVHNDLM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A1K6", "url": "https://www.orthodb.org/?gene=A0A8V1A1K6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AE21", "url": "https://www.orthodb.org/?gene=A0A8V1AE21", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24026", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24026", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24026:SF126", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24026:SF126", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A1K6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1K6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A1K6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1K6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AE21", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE21", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AE21-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE21-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTSLQMMGWRLRLFMRAVKRWKSVASWAMLLWDWWKQAPLGCPPSPSGHDRRLAGSRPPGRPPSAPRGRAMLASLRRTLPERLSRKAGGLPRRREGSVGGRRRGSAPTSGRSIQFSTRSAKQLSPSTSGCRLRLCDSSDTVQSLPSAGSSARHCSSCQAMGAYGHLTFLLLLLRAPGTFVKSAALPDLPRTVTLSEDAAPGARVAELAVSCSNASSSPQVTLQRVESGVPTGSNVTPLHTDPGHPFNPIAISADGAPPSTFRAEVTLRAGAELDAHRVNWYALMLRAACPGEQEVTGQLYVQVTSGQALRCDLKFASAGGDVVWVSANVAPRAPLYAVRAQPPGGLMFQLRNSGTPLTLTRQGLVLAPDGGFSPSKDTQTFRLEIDVMDRRGQNCSGAVTVEVRPSSRPRVTILAPQQDVLVPEGIGPLEVVTQVRASGDNVRYAILAPTSPALFTIDEMTGEIRSTRRLEVVSAHLLVRAYNALQPSDQDSAVLNVTVRGTEQRAPSCVPALYTSQVRETVSPGSPLVTLRCTDPGGDEGSLRYMLEGPPGSRSHFHMEGPQLKVNTTLDYDTEAMAAVGFHLTATIVVTAGGQPLRSTRVPVLVTVLPVNEFTPECPNGIVFTVSETAPFGSSVGRVVGTDRDHPPDSLEYSLEGGTGPAQPFSIDARTGEIRVVGPLGPPAACWLPADGAADRQPQ", "length": 699, "header": "tr|A0A8V1AE21-1|A0A8V1AE21_CHICK Isoform 1 of Cadherin domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1AE21-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A1K6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE21/entry#A0A8V1A1K6-1", "sequence": { "sequence": "MMGWRLRLFMRAVKRWKSVASWAMLLWDWWKQAPLGCPPSPSGHDRRLAGSRPPGRPPSAPRGRAMLASLRRTLPERLSRKAGGLPRRREGSVGGRRRGSAPTSGRSIQFSTRSAKQLSPSTSGCRLRLCDSSDTVQSLPSAGSSARHCSSCQAMGAYGHLTFLLLLLRAPGTFVKSAALPDLPRTVTLSEDAAPGARVAELAVSCSNASSSPQVTLQRVESGVPTGSNVTPLHTDPGHPFNPIAISADGAPPSTFRAEVTLRAGAELDAHRVNWYALMLRAACPGEQEVTGQLYVQVTSGQALRCDLKFASAGGDVVWVSANVAPRAPLYAVRAQPPGGLMFQLRNSGTPLTLTRQGLVLAPDGGFSPSKDTQTFRLEIDVMDRRGQNCSGAVTVEVRPSSRPRVTILAPQQDVLVPEGIGPLEVVTQVRASGDNVRYAILAPTSPALFTIDEMTGEIRSTRRLEVVSAHLLVRAYNALQPSDQDSAVLNVTVRGTEQRAPSCVPALYTSQVRETVSPGSPLVTLRCTDPGGDEGSLRYMLEGPPGSRSHFHMEGPQLKVNTTLDYDTEAMAAVGFHLTATIVVTAGGQPLRSSECPYPLHPVPISPSPWGRSRYRCAKFPLDPQTNTQRRKCSSPVAPVMPNPEGILDAIPEGNPVMAP", "length": 661, "header": "tr|A0A8V1A1K6-1|A0A8V1AE21_CHICK Computationally mapped isoform of Cadherin domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1AE21-1" }, "locus": { "chromosome": "12", "start_pos": 2593496, "end_pos": 2588331, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065277.1", "url": "https://www.ensembl.org/id/ENSGALT00010065277.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039739.1", "url": "https://www.ensembl.org/id/ENSGALP00010039739.1" } ] } }, { "isoform_ac": "A0A8V1AE21-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE21/entry#A0A8V1AE21-1", "sequence": { "sequence": "MTSLQMMGWRLRLFMRAVKRWKSVASWAMLLWDWWKQAPLGCPPSPSGHDRRLAGSRPPGRPPSAPRGRAMLASLRRTLPERLSRKAGGLPRRREGSVGGRRRGSAPTSGRSIQFSTRSAKQLSPSTSGCRLRLCDSSDTVQSLPSAGSSARHCSSCQAMGAYGHLTFLLLLLRAPGTFVKSAALPDLPRTVTLSEDAAPGARVAELAVSCSNASSSPQVTLQRVESGVPTGSNVTPLHTDPGHPFNPIAISADGAPPSTFRAEVTLRAGAELDAHRVNWYALMLRAACPGEQEVTGQLYVQVTSGQALRCDLKFASAGGDVVWVSANVAPRAPLYAVRAQPPGGLMFQLRNSGTPLTLTRQGLVLAPDGGFSPSKDTQTFRLEIDVMDRRGQNCSGAVTVEVRPSSRPRVTILAPQQDVLVPEGIGPLEVVTQVRASGDNVRYAILAPTSPALFTIDEMTGEIRSTRRLEVVSAHLLVRAYNALQPSDQDSAVLNVTVRGTEQRAPSCVPALYTSQVRETVSPGSPLVTLRCTDPGGDEGSLRYMLEGPPGSRSHFHMEGPQLKVNTTLDYDTEAMAAVGFHLTATIVVTAGGQPLRSTRVPVLVTVLPVNEFTPECPNGIVFTVSETAPFGSSVGRVVGTDRDHPPDSLEYSLEGGTGPAQPFSIDARTGEIRVVGPLGPPAACWLPADGAADRQPQ", "length": 699, "header": "tr|A0A8V1AE21-1|A0A8V1AE21_CHICK Isoform 1 of Cadherin domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1AE21-1" }, "locus": { "chromosome": "12", "start_pos": 2593511, "end_pos": 2587857, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065278.1", "url": "https://www.ensembl.org/id/ENSGALT00010065278.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039740.1", "url": "https://www.ensembl.org/id/ENSGALP00010039740.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 108, "start_aa": "Thr", "end_pos": 108, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr108", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0ABK0LKF4-1", "protein_name": "Cadherin-related family member 4", "gene_name": "Cdhr4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MMMLRLLEFLFALLIPVFPSLPWSTDILESKGPGTVLQTFLFNCSSYMPTLELLSVKPPTSFFNKPSLQGQKGLYRGKVTLSSSARLDALAVNYYELQLRYTCGNFVVDGSFFVHVLRDPGRIHCTGAFASPAGEFIYVPETVTPGALLYTLLLPGLGGQRAQMNITSAQDPPVFPGPFSIDEHGLLRAPSQGLRGQAQKTFQLQILVSLGKSQRCKGMLTVKVLPAPPSHVSFLKKAQSITIAEDLVPGSEVVQVQARGLNLLYEIISPRPSPLYSIGQADGVVRTTAPLDLVRVQGAVVTKLQVKAFERLRPWASAVSDLTVIVRAVNQRPPRCHPALLVTQIPETALEGTVLDTLTCVDPDSAGAPLDYQLRFHSPPDSASLRLRGRTLEVNATLDCDAPGACFQHLASILVSDGGQPQMTAEVPVLVMVTPVNEFSPSCMPHTFRVREDAGPYTLLGSIVGTDVDHPRNSLEYHISGGLSTFAVDRLSGELHLLGPLDYEQQRLYRIVILLIDHSQDWDLNSHRSGSCTITIEVEDVNDHAPECEPPFQELTIYTALGRSMEVTKVSCWIPQEPQRLTLSYSIMGGNSQSRFRLQGTILVYNDTVLGPPWPEPPSTHELLIHVADMGPSTPHLSTTATIIVHLVPWKASTVATSTHQSTVSSTMTPLIVTDVEAFWKPEPWFVVVLTATGAVLLLALGWLLGRILRRLAQSLQAPSKPARAQLLNSIQGSRGSIERQMEAPSMEMSKQHFDGRAQDVCNFSEAPVVPDDDPDLVLSQLFGEGKGDGGTGRDYLFSTLTGARRWL", "length": 808 }, "evidence": [ { "id": "A0A8V1AE21", "url": "https://omabrowser.org/oma/group/A0A8V1AE21/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A6H8M9-1", "protein_name": "Cadherin-related family member 4", "gene_name": "CDHR4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVLLRLLVFLFAPVVSDLCSLPCFINVSESQGPGTVLQFLSFNCSSYTPTPTLELLNVQPPTTFFNPPSLARWQGTYVGKLTLSSSAQLDALMVNHYKVQLKFTCGNHVMEGSLSVDVQRDLSHIQCAGQFASPAGEMIQVPETVTPGARLYTLLLPGLELHGAQMSIISAQDLPHFPGPFSINEQGWLQAPSQGLLGQAQKVFQLQISVSFGQRQSCQGMVIVKVLPVPSSQVSFLEQAQNITIPENLAPGSEVVQVQARGVDLRYEILSPVPSPLFSIGRADGVVRTTTPLELARTSGTAVSRLQVKAFEQGQLWASAKLNLTMNVQLVNLWPPRCLPALLVSQIPETAPVGTVLNTLTCEDPDSVGATLDYKLWFRSSSNPASLCLYDRVLEVNATLDCDTPGACFQHAASILVLDGGQPQMTTEVPVLVMVTPINEFSPACAPRTFRVQEDAAPHTLLGSVVGTDMDYPHDNIEYYTSGGPTTFAVDRLSGEVHLLGPLDYEQQRLYRLTVLVIDHGQDQNPNHHLSGSCTITIEVEDVNDHAPECEPPFQELTIYAPLGRSVEVTKMSCQIPQEPQRLIYSYSIVGGNSQNRFILQGAILVHSDLVLGPFWPEQPRTYELLICVADAGPSTPHLSTTATIIVHLVPRRASTVATSTHRTTVPSTMTPMLVTDTEAFWQPQPWFVVVLTATGALLLLALGWLLGRLLQGLAQLLQAPSKPAQALLLNSIQGTEGSIEGFLEAPKMEMSQAPSSVMSLHFDGRAQDSRTGRDYLFNTHTGARRWL", "length": 788 }, "evidence": [ { "id": "A0A8V1AE21", "url": "https://omabrowser.org/oma/group/A0A8V1AE21/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "F1N1M6-1", "protein_name": "Cadherin related family member 4", "gene_name": "CDHR4", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MVLLRPLALLLALVVSELYCLSWFIDVSESQGPGATLQSFSFNCSPYIPTLELLHVQPPTTFFNPPSLTRWQGTYVGKMTLSSSARLDALTVNHYELQLRFTCGNQVTEGRLSVNVQRDPNRDQCAGRFASPAGEIIQVRETVTPGTPLYTLLLPGQGAQMNITSAQDPPYFPGPFSIDGQGQLWAPSQGLKGQAQKVFQLQILVTFGQGRSCRGMLTVKVLPVSSSQVSFPQQAQNITIPENLVPGSKVAQVHARGFDVRYEIVSPVPCRLFSIARVDGVVRTTAPLELAQAPDAAVTRLRVKAFERLRPWDSAELDFQVDVQSVNRWPPRCLPALLATQIPETTPVGTFVNTFTCTDPDSPGSTLDYQLLFHSPASASSLCLRDGVLEVNDTLDCDAPGACLQHTASILVLDSGQPPMTTEVPVLVMVTPVNEFSPTCVSRTFRVREDARPHTLLGSVMGTDLDYPHDSIEYSISGGSAPFAVDSLNGEVHLLGPLDYEMQKSYRLTVLLTDHSQDQDPTCHRSGSCTITIEVEDVNDHAPECEPPFQELTVYAHLGRSLEVTTVSCRVAQEPQRLAFSYRIVGGNSQSRFSLQGAVLVHNDLMLAPPWPEQSHTYELLIRVADAGPSTPHLSTTATVIVHIVPWRASTGATSIHRTTVPSRMTPLLVTDTEVFWQPEPWFVVVLTVTSALLLLGLGWFLSWLLRGLTQVLQTSSKPTQALLLNSIQGTKGSIEGFVEAPRMETPQAPSSVMSLHHFDGRAQDSRTGRDYLFNTHTGARRWL", "length": 784 }, "evidence": [ { "id": "A0A8V1AE21", "url": "https://omabrowser.org/oma/group/A0A8V1AE21/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "H3BJZ2-1", "protein_name": "Cadherin-related family member 4", "gene_name": "Cdhr4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALLRLLEFLFALLIPVLYSLPWTMYISENNGPGTVLRPFSFNCSSYMPTLELLSVRPPTSFFNKPSMHGDKGVYLVMVSLSSSARLDALAVNQYELQLQYRCGNFVVDGSIFVHVQRDPGRIRCTGAFASPAGEFIYVPETITPGALVYTLLLPGVQRAQINITSAQNPSPGPFSIDEQGLLRAPSQGLRGQAQKTFQLQISVSFEKNQSCRGMLTVKVLPAPSSQVSFLQKAQSITISEDLVPGSEVVRVQATGFNLLYEIISPRPSLFYSIGQADGVVRTTAPLDLARVQGAMVTKLQVRAFERPRPWASAVFDLTVSVRAVNQWPPRCHPALLVTQIPETSLVGTVLDALTCVDPDSAGRPLDYQLRFHSPPDSASLRLRDRILEVNATLDCDTPGACFQHSASILVVDGGQPQMTTEIPVLVMVTPVNEFSPACVPRTFRVQEDTGPHTLLGSIVGTDMDYPRNSLEYYISGGPSTFAVDRLSGELHLLGPLDYEQQRLYKITILLIDHSQDWDLNSHRSGSCTITIEVEDVNDHAPECEPPFQELTIYTPMGHSMEVTKVSCWIPQEPQRLTLSYSIVGGNSQSRFRLQGAILVYNDTVLGPPWPEQPCTYELLIHVADVGPSIPHLSTTTTIIVHLVPWKASTVATSTHQSTVSSTMTPLIVTELEAFWKPEPWFVVVLTATGAVLLLALGWLLSRILRGLAPSLQAPSKPAKAQLLNSIQGNEGPIERQMEAPRIEMSQVPRTAMSLQHFDGRAQDVCMGRDYLFNTLTGARRWL", "length": 783 }, "evidence": [ { "id": "A0A8V1AE21", "url": "https://omabrowser.org/oma/group/A0A8V1AE21/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AE21", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE21" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AE21", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE21" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "homophilic cell adhesion via plasma membrane adhesion molecules", "id": "GO:0007156", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007156", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AE21", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE21" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 213, "end_pos": 215, "annotation": "n_glycosylation_sequon" }, { "start_pos": 234, "end_pos": 236, "annotation": "n_glycosylation_sequon" }, { "start_pos": 394, "end_pos": 396, "annotation": "n_glycosylation_sequon" }, { "start_pos": 496, "end_pos": 498, "annotation": "n_glycosylation_sequon" }, { "start_pos": 567, "end_pos": 569, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AE21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE21" }, { "id": "PS50268", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50268" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Cadherin", "eco_id": "ECO_0000259", "start_pos": 510, "end_pos": 618, "start_aa": "Val", "end_aa": "Cys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 108 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 213, "end_pos": 215 }, { "start_pos": 234, "end_pos": 236 }, { "start_pos": 394, "end_pos": 396 }, { "start_pos": 496, "end_pos": 498 }, { "start_pos": 567, "end_pos": 569 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AD99-1", "uniprot_ac": "A0A8V1AD99", "uniprot_id": "A0A8V1AD99_CHICK", "mass": { "chemical_mass": 127644.0, "monoisotopic_mass": 127644.0 }, "refseq": {}, "gene_names": [ { "name": "PEAR1", "type": "recommended", "evidence": [ { "id": "A0A8V1AD99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD99" } ] } ], "protein_names": [ { "name": "Platelet endothelial aggregation receptor 1", "type": "synonym", "evidence": [ { "id": "A0A8V1AD99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD99/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AD99", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD99" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PEAR1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD99", "locus": { "chromosome": "25", "start_pos": 1096825, "end_pos": 1087676, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027784", "url": "https://www.ensembl.org/id/ENSGALG00010027784" } ] } } ], "crossref": [ { "id": "A0A8V1AD99", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AD99", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00054", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00054", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd00055", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00055", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100857779", "url": "https://www.ncbi.nlm.nih.gov/gene/100857779", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000742", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000742", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002049", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002049", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011489", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011489", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013032", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013032", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052485", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052485", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057138", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057138", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:100857779", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100857779", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CPRDTHG", "url": "https://omabrowser.org/oma/group/CPRDTHG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A5L6", "url": "https://www.orthodb.org/?gene=A0A8V1A5L6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AD99", "url": "https://www.orthodb.org/?gene=A0A8V1AD99", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24052", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24052", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24052:SF12", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24052:SF12", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00053", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00053", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12661", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12661", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23301", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23301", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1A5L6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5L6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A5L6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5L6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AD99", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD99", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AD99-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD99-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPGCIPCCPPAPHVRSWDSSARWPRCKVMSTNALHPALGMGQPDVPSFPSLLHIHPQGQITPVPSSAPIHGLPPVLCERSHSQDGVFGAHLRSSCTVGLSDTQAGGDAQRRGAGWAQLHGLSTSICLWGPHSTAATRVAVPQFPFGSQAGLEPFPGTQECRPSPAGRPGVVGGEWKSSVCESGLVLPCRMVLRTVALALHACLLAALHPSDPNVCSYWESFTVAVKESYAKPHIVTSTEPCTGTPGLPQSCPQQRVVYRTEYRQAVRTDYRRRYQCCLGYYESRDACVPRCTQECVHGRCVAPERCQCEPGWRGHDCSSACDERLWGKNCEHHCDCHHGAPCNPLSGVCACPPGFTPPLCHQPCPPGSYGPDCRLHCPCHHGAPCNASTGACLCPPGLAGPLCEVLCPEGTPCGTHCPCQNGGICHPPGSSTCVCPHGWMGDICSIPCPPGRFGPSCQGECRCHNGGRCDPLGGQCRCAPGFTGEQCRERCPVGRYGQDCQESCDCANGGQCFHVDGACLCEAGFQGSRCEEPRCLPGLYGIQCQSRCLCHPQHSQSCHPLLGECSCRPGWAGLFCNESCPPGSFGAGCLQLCLCLNGGTCDGTTGRCHCPPGYTDEHCSSLCPSDTFGVNCSEHCSCQHGVACSPIDGSCICKEGWHGPDCSTPCPDGTWGPGCNQSCDCAHGATCSAQSGVCSCTPGWHGPRCHQSCPNGTFGAGCGQRCECDHADGCDPITGECHCLPGWTGLQCKQSCPQGSWGRGCRQLCVCRNGASCSPEDGSCTCTPGFRGPTCQRQCPPGRYGKRCALSCSCANGSSCHHATGACLCAAGWSGPHCSQPCTPGSWGDACSQRCQCHQRGTCDPVEGTCHCPAGWTGSSCEEECPPGTFGLQCEQLCRCPHNATCHPVSGTCPCAPGRSGPHCEAGNPDQPYTIVPAPPLAYSTLGMVVSLVALVALLVAVVAVALCYRHRQKGKENRHLAVAYTAGRTDTSEYVVPDVPPNHTHYYSNPSYHTLSQCTLPAHSSQDRASSLKVPTSQPFHGAERPYGPEGNATLPPDWKHLGAPPQEARGGGQMDRSYSYSYSCSMGKYYGTEHPQEGLRASGSSLASENPYATIKDVPSPLAKASEGSYMEMKSPVQREMSYAEIGLLEEPDGNEEESSPGGAEDTAAARDVRSHYDSPKNSHIPSHYDVPPVRHPPSPPLRRKDR", "length": 1205, "header": "tr|A0A8V1AD99-1|A0A8V1AD99_CHICK Isoform 1 of Platelet endothelial aggregation receptor 1 OS=Gallus gallus OX=9031 GN=PEAR1 PE=3 SV=1 CANONICAL=A0A8V1AD99-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A5L6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD99/entry#A0A8V1A5L6-1", "sequence": { "sequence": "MVLRTVALALHACLLAALHPSDPNVCSYWESFTVAVKESYAKPHIVTSTEPCTGTPGLPQSCPQQRVVYRTEYRQAVRTDYRRRYQCCLGYYESRDACVPRCTQECVHGRCVAPERCQCEPGWRGHDCSSACDERLWGKNCEHHCDCHHGAPCNPLSGVCACPPGFTPPLCHQPCPPGSYGPDCRLHCPCHHGAPCNASTGACLCPPGLAGPLCEVLCPEGTPCGTHCPCQNGGICHPPGSSTCVCPHGWMGDICSIPCPPGRFGPSCQGECRCHNGGRCDPLGGQCRCAPGFTGEQCRERCPVGRYGQDCQESCDCANGGQCFHVDGACLCEAGFQGSRCEEPRCLPGLYGIQCQSRCLCHPQHSQSCHPLLGECSCRPGWAGLFCNESCPPGSFGAGCLQLCLCLNGGTCDGTTGRCHCPPGYTDEHCSSLCPSDTFGVNCSEHCSCQHGVACSPIDGSCICKEGWHGPDCSTPCPDGTWGPGCNQSCDCAHGATCSAQSGVCSCTPGWHGPRCHQSCPNGTFGAGCGQRCECDHADGCDPITGECHCLPGWTGLQCKQSCPQGSWGRGCRQLCVCRNGASCSPEDGSCTCTPGFRGPTCQRQCPPGRYGKRCALSCSCANGSSCHHATGACLCAAGWSGPHCSQPCTPGSWGDACSQRCQCHQRGTCDPVEGTCHCPAGWTGSSCEEECPPGTFGLQCEQLCRCPHNATCHPVSGTCPCAPGRSGPHCEAGNPDQPYTIVPAPPLAYSTLGMVVSLVALVALLVAVVAVALCYRHRQKGKENRHLAVAYTAGRTDTSEYVVPDVPPNHTHYYSNPSYHTLSQCTLPAHSSQDRASSLKVPTSQPFHGAERPYGPEGNATLPPDWKHLGAPPQEARGGGQMDRSYSYSYSCSMGKYYGTEHPQEGLRASGSSLASENPYATIKDVPSPLAKASEGSYMEMKSPVQREMSYAEIGLLEEPDGNEEESSPGGAEDTAAARDVRSHYDSPKNSHIPSHYDVPPVRHPPSPPLRRKDR", "length": 1016, "header": "tr|A0A8V1A5L6-1|A0A8V1AD99_CHICK Computationally mapped isoform of Platelet endothelial aggregation receptor 1 OS=Gallus gallus OX=9031 GN=PEAR1 PE=3 SV=1 CANONICAL=A0A8V1AD99-1" }, "locus": { "chromosome": "25", "start_pos": 1096602, "end_pos": 1090371, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067329.1", "url": "https://www.ensembl.org/id/ENSGALT00010067329.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041194.1", "url": "https://www.ensembl.org/id/ENSGALP00010041194.1" } ] } }, { "isoform_ac": "A0A8V1AD99-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD99/entry#A0A8V1AD99-1", "sequence": { "sequence": "MPGCIPCCPPAPHVRSWDSSARWPRCKVMSTNALHPALGMGQPDVPSFPSLLHIHPQGQITPVPSSAPIHGLPPVLCERSHSQDGVFGAHLRSSCTVGLSDTQAGGDAQRRGAGWAQLHGLSTSICLWGPHSTAATRVAVPQFPFGSQAGLEPFPGTQECRPSPAGRPGVVGGEWKSSVCESGLVLPCRMVLRTVALALHACLLAALHPSDPNVCSYWESFTVAVKESYAKPHIVTSTEPCTGTPGLPQSCPQQRVVYRTEYRQAVRTDYRRRYQCCLGYYESRDACVPRCTQECVHGRCVAPERCQCEPGWRGHDCSSACDERLWGKNCEHHCDCHHGAPCNPLSGVCACPPGFTPPLCHQPCPPGSYGPDCRLHCPCHHGAPCNASTGACLCPPGLAGPLCEVLCPEGTPCGTHCPCQNGGICHPPGSSTCVCPHGWMGDICSIPCPPGRFGPSCQGECRCHNGGRCDPLGGQCRCAPGFTGEQCRERCPVGRYGQDCQESCDCANGGQCFHVDGACLCEAGFQGSRCEEPRCLPGLYGIQCQSRCLCHPQHSQSCHPLLGECSCRPGWAGLFCNESCPPGSFGAGCLQLCLCLNGGTCDGTTGRCHCPPGYTDEHCSSLCPSDTFGVNCSEHCSCQHGVACSPIDGSCICKEGWHGPDCSTPCPDGTWGPGCNQSCDCAHGATCSAQSGVCSCTPGWHGPRCHQSCPNGTFGAGCGQRCECDHADGCDPITGECHCLPGWTGLQCKQSCPQGSWGRGCRQLCVCRNGASCSPEDGSCTCTPGFRGPTCQRQCPPGRYGKRCALSCSCANGSSCHHATGACLCAAGWSGPHCSQPCTPGSWGDACSQRCQCHQRGTCDPVEGTCHCPAGWTGSSCEEECPPGTFGLQCEQLCRCPHNATCHPVSGTCPCAPGRSGPHCEAGNPDQPYTIVPAPPLAYSTLGMVVSLVALVALLVAVVAVALCYRHRQKGKENRHLAVAYTAGRTDTSEYVVPDVPPNHTHYYSNPSYHTLSQCTLPAHSSQDRASSLKVPTSQPFHGAERPYGPEGNATLPPDWKHLGAPPQEARGGGQMDRSYSYSYSCSMGKYYGTEHPQEGLRASGSSLASENPYATIKDVPSPLAKASEGSYMEMKSPVQREMSYAEIGLLEEPDGNEEESSPGGAEDTAAARDVRSHYDSPKNSHIPSHYDVPPVRHPPSPPLRRKDR", "length": 1205, "header": "tr|A0A8V1AD99-1|A0A8V1AD99_CHICK Isoform 1 of Platelet endothelial aggregation receptor 1 OS=Gallus gallus OX=9031 GN=PEAR1 PE=3 SV=1 CANONICAL=A0A8V1AD99-1" }, "locus": { "chromosome": "25", "start_pos": 1096602, "end_pos": 1089804, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067327.1", "url": "https://www.ensembl.org/id/ENSGALT00010067327.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041193.1", "url": "https://www.ensembl.org/id/ENSGALP00010041193.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 244, "start_aa": "Thr", "end_pos": 244, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr244", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:100857779", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100857779", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "E7F8N2-1", "protein_name": "Uncharacterized protein pear1", "gene_name": "pear1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MKTAEICVVLFVLGCVCELSLSLDPRDPNVCSLWESFTTSVKESYAQPFDQMSEEPCSEPWSANKCTRHRITYKTLYRQVVKMDYRRRYQCCPGFYESRNKCVPRCTKECVHGRCVAPDRCQCEMGWRGDDCSSSCDGQHWGPGCRRLCECQNGGECDVLTGNCQCPAGYTGQHCHDPCPVKWFGQGCRQECQCGTGGICNQTTGECVCKQGFTGTLCEESCPRPKRCAARCPCQNGGICQGNGVCLCPPGWMGPVCTERCPPGRFGINCSKDCLCHNGGHCDQEKGQCQCDAGYTGERCNEECPVGTYGEDCKGVCDCANGARCYNIHGGCLCEPGFKGPRCDHRMCPEAVFGMHCQHRCLCNPLNTLSCHPLKGECTCQPGWAGLYCNETCAQGYYGNGCLEPCLCVNGGVCDSVTGQCHCPPGFTGLHCEKLCEDGFYGKGCLSACKCVNSIVCSPVDGACICKEGWRGPDCSIACSEGTWGPGCNRTCKCTNGASCDPADGSCKCTAGWRGASCDEPCLIGTFGPGCQNQCDCVHDEGCESVTGQCLCLPGWTGVRCTQQCPEGTWGIQCNQTCSCLNSATCQAHTGTCLCKPGFWGAQCQHMCSAGLFGEKCSRHCPPCVHASSCHHITGDCQCLSGYTGPLCEQACPVGRYGSHCSNVCRCTNNATCHHEVGLCICPAGWTGSDCSLLCQAGTFGINCAQTCSCPPNHSCDPHNGDCVCEPGPGEACKPEQELSVMVPVSPVERDSWGAIAGIVVLVILVVLLLAVLLLYRRRQQDKQSNTPVVSFSSTRTVSSEYAVPDVPHSYHHYYSNPSYHTLSQNRPPLPHLPNNQDRAIKNTNNQLFCSLKNMERERRGLFTADTNATLPPGWKHQEPPKDPGAFGIDRSYSYSATLGKHYNKELKDSCVAVSSSSLNSENPYATIKDLPGLPVCPPESSYMEMKSAVPRQRSYTQIISPPLMTAPALPCTGHCSLSNAEEQELQNHYDLPINSHIPGHYDLPPVRRPPSPSPRRLPN", "length": 1020 }, "evidence": [ { "id": "A0A8V1AD99", "url": "https://omabrowser.org/oma/group/A0A8V1AD99/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E9PTZ1-1", "protein_name": "Platelet endothelial aggregation receptor 1", "gene_name": "Pear1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPLCPLLLLALGLRLAGTLNSNDPNVCTFWESFTTTTKESHLRPFSLPPAESCDRPWEDPHTCAQPTVVYRTVYRQVVKMDSRPRLQCCGGYYESSGACVPLCAQECVHGRCVAPNRCQCAPGWRGDDCSSECAPGMWGPQCDRLCLCGNSSSCDPRSGVCFCPSGLQPPDCLQPCPDGHYGPACQFDCHCYGASCDPRDGACFCPPGRTGPSCNVPCSQGTDGFFCPRTYPCQNGGVPQGSQGSCSCPPGWMGVICSLPCPEGFHGPNCTQECRCHNGGLCDRFTGQCHCAPGYIGDRCREECPVGRFGQDCAETCDCAPGARCFPANGACLCEHGFTGDRCTERLCPDGRYGLSCQDPCTCDPEHSLSCHPMHGECSCQPGWAGLHCNESCPQDTHGAGCQEHCLCLHGGVCLADSGLCRCAPGYTGPHCANLCPPNTYGINCSSHCSCENAIACSPVDGTCICKEGWQRGNCSVPCPPGTWGFSCNASCQCAHEGVCSPQTGACTCTPGWRGVHCQLPCPKGQFGEGCASVCDCDHSDGCDPVHGHCRCQAGWMGTRCHLPCPEGFWGANCSNACTCKNGGTCVPENGNCVCAPGFRGPSCQRPCPPGRYGKRCVPCKCNNHSSCHPSDGTCSCLAGWTGPDCSESCPPGHWGLKCSQPCQCHHGATCHPQDGSCVCIPGRTGPNCSEGCPSRMFGVNCSQLCQCDPGEMCHPETGACVCPPGHSGAHCKVGSQESFTIMPTSPVIHNSLGAVIGIAVLGTLVVALVALFIGYRHWQKGKEHEHLAVAYSTGRLDGSDYVMPDVSPSYSHYYSNPSYHTLSQCSPNLPPPNKIPGSQLFVSSQASERPNRNHGRDNHATLPADWKHRRESHDRGTSHLDRRYSCSYGHRNGPGPFCHKGPISEEGLGASVMSLSSENPYATIRDLPGLPGEPRESSYVEMKGPPSVSPPRQPLHLRDRQQQQLQSQRDSGTYEQPTPLSRNEESVGSMPPLPPGLPPGHYDSPKNSHIPGHYDLPPVRHPPSPPSRRQDR", "length": 1033 }, "evidence": [ { "id": "A0A8V1AD99", "url": "https://omabrowser.org/oma/group/A0A8V1AD99/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1RHK7-1", "protein_name": "Platelet endothelial aggregation receptor 1", "gene_name": "PEAR1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSPPLRSLLLLALALGLAGTLNPKDPNTCSFWESFTTTTKESHLRPFSLLPSEPCDRPWESPHTCPRPTVVYRTVYRQVVKTEHRKRLQCCQGFYESRGACVPLCSQECVHGRCVAPNQCQCVQDWRGDDCSSACAPGVWGPQCDKPCNCGNSSSCDPKSGACSCPPGLQPPHCLQPCSPGRYGPACQYSCQCHRAPCDPQTGACLCPPERTGPSCEESCSLSTFGFSCPSIPPCHNGGVFQASQGSCSCPPGWMGTICSLPCPEGFHGPNCSQECRCHNGGLCDRFTGQCRCAPGYTGDRCREECPVGYFGQDCAEMCDCAPGARCFPANGACLCEHGFTGDRCAERLCPDGLYGLSCQVPCTCDPEHSFSCHPMSGECSCLPGWAGLHCNESCPQDTHGPGCQEHCLCLHGGVCQPDSGLCRCAPGYTGPHCASLCPPDSYGVNCSSRCSCENAIACSPVDGACICKEGWQRGNCSIPCPPGTWGFNCNASCQCAHGAACSPQTGACTCTPGWHGAHCQLPCPKGQFGEGCASHCDCDHSDGCDPVHGRCHCQAGWTGTRCHLPCPEGFWGTNCSNTCTCKNGGTCIPENGNCVCAPGFRGPSCQRPCQPGRYGKRCVPCKCANHSSCHPSNGTCYCLAGWTGPDCSQPCPLGHWGANCAQLCQCRHGGTCHPQDGSCFCPPGWIGHLCLEGCPPGMFGANCSQPCQCGSGERCHPETGACVCPPGHSGAPCRIGSQEPFTMMPTAPVAYSSVGAVIGIAVLGSLVVALVVLFIGYRHWQKGKEHQHLAVAYSSGRLDGSEYVMPDVPPSYSHYYSNPSYHTLCSPNPPPPNKVPGSQLFVSLQTPERPGGTPGHENHATLPADWKHRREPPPGPLDRGSSRLDRSYSCSYSNSNGPGPFYSKGPISEEGLGASMASLSSENPYATIRDLPSLLGSPRESSYVEMKGPPSGSPPRQPPQLRDSQRRRHPQPQRDSGTYEQPSPLTHDRDSMGSQPPLPPGLPPGHYDSPKNSHIPGHYDLPPVRHPPSPPLRRQDR", "length": 1038 }, "evidence": [ { "id": "A0A8V1AD99", "url": "https://omabrowser.org/oma/group/A0A8V1AD99/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q5VY43-1", "protein_name": "Platelet endothelial aggregation receptor 1", "gene_name": "PEAR1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSPPLCPLLLLAVGLRLAGTLNPSDPNTCSFWESFTTTTKESHSRPFSLLPSEPCERPWEGPHTCPQPTVVYRTVYRQVVKTDHRQRLQCCHGFYESRGFCVPLCAQECVHGRCVAPNQCQCVPGWRGDDCSSECAPGMWGPQCDKPCSCGNNSSCDPKSGVCSCPSGLQPPNCLQPCTPGYYGPACQFRCQCHGAPCDPQTGACFCPAERTGPSCDVSCSQGTSGFFCPSTHSCQNGGVFQTPQGSCSCPPGWMGTICSLPCPEGFHGPNCSQECRCHNGGLCDRFTGQCRCAPGYTGDRCREECPVGRFGQDCAETCDCAPDARCFPANGACLCEHGFTGDRCTDRLCPDGFYGLSCQAPCTCDREHSLSCHPMNGECSCLPGWAGLHCNESCPQDTHGPGCQEHCLCLHGGVCQATSGLCQCAPGYTGPHCASLCPPDTYGVNCSARCSCENAIACSPIDGECVCKEGWQRGNCSVPCPPGTWGFSCNASCQCAHEAVCSPQTGACTCTPGWHGAHCQLPCPKGQFGEGCASRCDCDHSDGCDPVHGRCQCQAGWMGARCHLSCPEGLWGVNCSNTCTCKNGGTCLPENGNCVCAPGFRGPSCQRSCQPGRYGKRCVPCKCANHSFCHPSNGTCYCLAGWTGPDCSQPCPPGHWGENCAQTCQCHHGGTCHPQDGSCICPLGWTGHHCLEGCPLGTFGANCSQPCQCGPGEKCHPETGACVCPPGHSGAPCRIGIQEPFTVMPTTPVAYNSLGAVIGIAVLGSLVVALVALFIGYRHWQKGKEHHHLAVAYSSGRLDGSEYVMPDVPPSYSHYYSNPSYHTLSQCSPNPPPPNKVPGPLFASLQNPERPGGAQGHDNHTTLPADWKHRREPPPGPLDRGSSRLDRSYSYSYSNGPGPFYNKGLISEEELGASVASLSSENPYATIRDLPSLPGGPRESSYMEMKGPPSGSPPRQPPQFWDSQRRRQPQPQRDSGTYEQPSPLIHDRDSVGSQPPLPPGLPPGHYDSPKNSHIPGHYDLPPVRHPPSPPLRRQDR", "length": 1037 }, "evidence": [ { "id": "A0A8V1AD99", "url": "https://omabrowser.org/oma/group/A0A8V1AD99/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8VIK5-1", "protein_name": "Platelet endothelial aggregation receptor 1", "gene_name": "Pear1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPLCPLLLLALGLRLTGTLNSNDPNVCTFWESFTTTTKESHLRPFSLLPAESCHRPWEDPHTCAQPTVVYRTVYRQVVKMDSRPRLQCCRGYYESRGACVPLCAQECVHGRCVAPNQCQCAPGWRGGDCSSECAPGMWGPQCDKFCHCGNNSSCDPKSGTCFCPSGLQPPNCLQPCPAGHYGPACQFDCQCYGASCDPQDGACFCPPGRAGPSCNVPCSQGTDGFFCPRTYPCQNGGVPQGSQGSCSCPPGWMGVICSLPCPEGFHGPNCTQECRCHNGGLCDRFTGQCHCAPGYIGDRCQEECPVGRFGQDCAETCDCAPGARCFPANGACLCEHGFTGDRCTERLCPDGRYGLSCQEPCTCDPEHSLSCHPMHGECSCQPGWAGLHCNESCPQDTHGPGCQEHCLCLHGGLCLADSGLCRCAPGYTGPHCANLCPPDTYGINCSSRCSCENAIACSPIDGTCICKEGWQRGNCSVPCPLGTWGFNCNASCQCAHDGVCSPQTGACTCTPGWHGAHCQLPCPKGQFGEGCASVCDCDHSDGCDPVHGQCRCQAGWMGTRCHLPCPEGFWGANCSNTCTCKNGGTCVSENGNCVCAPGFRGPSCQRPCPPGRYGKRCVQCKCNNNHSSCHPSDGTCSCLAGWTGPDCSEACPPGHWGLKCSQLCQCHHGGTCHPQDGSCICTPGWTGPNCLEGCPPRMFGVNCSQLCQCDLGEMCHPETGACVCPPGHSGADCKMGSQESFTIMPTSPVTHNSLGAVIGIAVLGTLVVALIALFIGYRQWQKGKEHEHLAVAYSTGRLDGSDYVMPDVSPSYSHYYSNPSYHTLSQCSPNPPPPNKVPGSQLFVSSQAPERPSRAHGRENHVTLPADWKHRREPHERGASHLDRSYSCSYSHRNGPGPFCHKGPISEEGLGASVMSLSSENPYATIRDLPSLPGEPRESGYVEMKGPPSVSPPRQSLHLRDRQQRQLQPQRDSGTYEQPSPLSHNEESLGSTPPLPPGLPPGHYDSPKNSHIPGHYDLPPVRHPPSPPSRRQDR", "length": 1034 }, "evidence": [ { "id": "A0A8V1AD99", "url": "https://omabrowser.org/oma/group/A0A8V1AD99/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AD99", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD99" } ], "pmid": "" }, { "name": "phagocytic cup", "id": "GO:0001891", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001891", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AD99", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD99" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AD99", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD99" } ], "pmid": "" }, { "name": "lamellipodium", "id": "GO:0030027", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030027", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AD99", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD99" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "platelet aggregation", "id": "GO:0070527", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070527", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AD99", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD99" } ], "pmid": "" }, { "name": "phosphatidylinositol 3-kinase/protein kinase B signal transduction", "id": "GO:0043491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043491", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AD99", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD99" } ], "pmid": "" }, { "name": "positive regulation of platelet activation", "id": "GO:0010572", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010572", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AD99", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD99" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "signaling receptor activity", "id": "GO:0038023", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038023", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AD99", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD99" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1049, "end_pos": 1051, "annotation": "n_glycosylation_sequon" }, { "start_pos": 386, "end_pos": 388, "annotation": "n_glycosylation_sequon" }, { "start_pos": 577, "end_pos": 579, "annotation": "n_glycosylation_sequon" }, { "start_pos": 631, "end_pos": 633, "annotation": "n_glycosylation_sequon" }, { "start_pos": 676, "end_pos": 678, "annotation": "n_glycosylation_sequon" }, { "start_pos": 711, "end_pos": 713, "annotation": "n_glycosylation_sequon" }, { "start_pos": 812, "end_pos": 814, "annotation": "n_glycosylation_sequon" }, { "start_pos": 899, "end_pos": 901, "annotation": "n_glycosylation_sequon" }, { "start_pos": 999, "end_pos": 1001, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AD99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD99" }, { "id": "PS50026", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50026" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EGF-like", "eco_id": "ECO_0000259", "start_pos": 369, "end_pos": 404, "start_aa": "Tyr", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1AD99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD99" }, { "id": "PS51041", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51041" } ], 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"field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AAT3-1", "uniprot_ac": "A0A8V1AAT3", "uniprot_id": "A0A8V1AAT3_CHICK", "mass": { "chemical_mass": 195899.0, "monoisotopic_mass": 195899.0 }, "refseq": { "ac": "XP_040559750", "name": "coiled-coil domain-containing protein 141 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040559750" }, "gene_names": [ { "name": "CCDC141", "type": "recommended", "evidence": [ { "id": "A0A8V1AAT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAT3" } ] }, { "name": "CCDC141", "type": "synonym", "evidence": [ { "id": "XP_040559750", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040559750" } ] } ], "protein_names": [ { "name": "Coiled-coil domain containing 141", "type": "synonym", "evidence": [ { "id": "A0A8V1AAT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAT3/entry#names_and_taxonomy" } ] }, { "name": "coiled-coil domain-containing protein 141 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_040559750", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040559750" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052538.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040559750", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040559750" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAT3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAT3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CCDC141", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAT3", "locus": { "chromosome": "7", "start_pos": 14753849, "end_pos": 14686738, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010026242", "url": "https://www.ensembl.org/id/ENSGALG00010026242" } ] } } ], "crossref": [ { "id": "cd00176", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00176", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "770766", "url": "https://www.ncbi.nlm.nih.gov/gene/770766", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013098", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013098", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018159", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018159", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050876", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050876", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058157", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058157", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "DAKAKPC", "url": "https://omabrowser.org/oma/group/DAKAKPC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AAT3", "url": "https://www.orthodb.org/?gene=A0A8V1AAT3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR42757", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR42757", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR42757:SF44", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR42757:SF44", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07679", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07679", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25101", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25101", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040559750", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040559750", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1A0H5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0H5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A0H5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0H5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A5M4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5M4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A5M4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5M4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A5M9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5M9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A5M9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5M9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A5N3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5N3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A5N3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5N3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A816", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A816", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A816-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A816-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AAT3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAT3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AAT3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAT3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSNEAGLEQKLSTTTLSSVAVQAGNASIVIAVLKCGKWVKLQLAESTPNLLEIGSNQDETRKLLQDHELLLTKLKALEDKVWDLLHEADKAAEENKEKSQVYDAMAETLGDAWDTLIIMLEKRQALLELTMVFFENALEFAVKIDQVEDFLKNAQEFDNIDNLRELLLQQEHHTKELLEKSLALLNKSHELTEFIEEFKREGPNANTEVIQGAQSSCLKIDSLLELLQDRRRQLDRSLKHQRQGLEQVLQICLWHQQENQVTSWYKKNIRDYIHKQNLGSSLLENEELLKEHKEMEVRLKEWSSTVEQLEAEAVKILLSEDYTEKEHLNLSSQKIHLLRGEVCCHMEERKALLQEANDFFNTAGKALDALENYLKIFNSEGLSLPVLSMKYDELKEEIKGCTASTLQKGQTLINKADSHSSWVIGIQKMMENVNEKEDQLIRQCPHDKELMLKKQQQTSSLEHHLNKVSQSIKKITLMLAVDVEIGSHLSESERILNEHLELANQIKETSCELAEAEGIIKDMKEFEPEQVAAFNSKTDFLNEELKKAERNISTKIEILSTYVAFLKSSLEVNDYIQNLKEFYQAEPLQTSREAENKNTMESVNTKWQKSIEKFFSTENLGRIFLNLVNTVNEGLILKVQKSVQVIEETIINLSKEMKELTDLWAVWNFKINQVKPIKQQCWILEEQLNKTTHGLQILQEALTLASTVDLGSDLCIALEQQKLNQMKPQFQQLNAELEYMMKLLELPSQKGFPMKENSERISELIHLHQMVKSTMTEYDEIFNKALKFHHVKKELECLSKSGELDFPEITVGPEDVHHAKAYLLNAQKKHMHIRQLYKLVINQGVDILSAVQKPNCLNVSVKNLKQELARLECDNINWSSKADKYEEELSQHFQYHIYQEEINELRESFKDLKKKFNNLKFNYTKKTEKARNLKALKIQIQQVDTYPEKIQILKKKIDNLEKRLVDTATNEPNVRVFLGSVSELQKQLNDFGIVVEDYKQNLGLTEHLQLMMEECQFCFEDVSATVIRVGKYSAECKTREAMETLYKQFNKFIESTVPQQEEKFQQIIDLAKQLYGFEEGNKYVEKAVSKYKEILNSVDELCKSLREFKEIQKDEFAGELVTVQKEGNSREECEDKADGKKYQMGSDMLLINSEYVTEKRNNILSPTNTKQERNKLADIPIICPAGEDLVSQDTELSSSAKEDSLQTEFLAEEIPSGDEYECISPDDISLPPLSETPESNLLHSETELEEQRCCSSRSLHASSYSLQMQKTSSDKRLMESSDLLTNSAYADATVTRMESPSAQLEKFCISSTDSGPKVRAGFPLASSLRAVSEASTASCTINAKPAYSTMSEVRKTHLQHLEIHKSMAEMREQLHDSNNCTKTQDRLHALPDAFSGFVFQSDATRSCQRQMVTREEIKSTSEKNSMACLTGQAPNFSQLLSNLTVTEGSPVTLEVEVTGIPEPTLTWYKKGQKVTADEHLKLYQKETKHALFIQKVCDNDAGLYVARAKNSSGTISSSAILHVQVQGKQPNFVQKFGHTTLQEGEDLILHCTVHGKPKPHVCWTKDDIQVVAGDVSTEKLGDNYYLLKRNVALADTGKYICVASNEVGKAHCSATVTVIEKNKNPEISTVTQAKSEWENGCFSEKGNVTAAELARAQDMCCVRGQRPVPRHLPVRFKEKLWLQGVYLELVRPPDISFSLEHVPGLLQPTAKDQKVDCT", "length": 1718, "header": "tr|A0A8V1AAT3-1|A0A8V1AAT3_CHICK Isoform 1 of Coiled-coil domain containing 141 OS=Gallus gallus OX=9031 GN=CCDC141 PE=3 SV=1 CANONICAL=A0A8V1AAT3-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A0H5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAT3/entry#A0A8V1A0H5-1", "sequence": { "sequence": "MSNEAGLEQKLSTTTLSSVAVQAGNASIVIAVLKCGKWVKLQLAESTPNLLEIGSNQDETRKLLQDHELLLTKLKALEDKVWDLLHEADKAAEENKEKSQVYDAMAETLGDAWDTLIIMLEKRQALLELTMVFFENALEFAVKIDQVEDFLKNAQEFDNIDNLRELLLQQEHHTKELLEKSLALLNKSHELTEFIEEFKREGPNANTEVIQGAQSSCLKIDSLLELLQDRRRQLDRSLKHQRQGLEQVLQICLWHQQENQVTSWYKKNIRDYIHKQNLGSSLLENEELLKEHKEMEVRLKEWSSTVEQLEAEAVKILLSEDYTEKEHLNLSSQKIHLLRGEVCCHMEERKALLQEANDFFNTAGKALDALENYLKIFNSEGLSLPVLSMKYDELKEEIKGCTASTLQKGQTLINKADSHSSWVIGIQKMMENVNEKEDQLIRQCPHDKELMLKKQQQTSSLEHHLNKVSQSIKKITLMLAVDVEIGSHLSESERILNEHLELANQIKETSCELAEAEGIIKDMKEFEPEQVAAFNSKTDFLNEELKKAERNISTKIEILSTYVAFLKSSLEVNDYIQNLKEFYQAEPLQTSREAENKNTMESVNTKWQKSIEKFFSTENLGRIFLNLVNTVNEGLILKVQKSVQVIEETIINLSKEMKELTDLWAVWNFKINQVKPIKQQCWILEEQLNKTTHGLQILQEALTLASTVDLGSDLCIALEQQKLNQMKPQFQQLNAELEYMMKLLELPSQKGFPMKENSERISELIHLHQMVKSTMTEYDEIFNKALKFHHVKKELECLSKSGELDFPEITVGPEDVHHAKAYLLNAQKKHMHIRQLYKLVINQGVDILSAVQKPNCLNVSVKNLKQELARLECDNINWSSKADKYEEELSQHFQYHIYQEEINELRESFKDLKKKFNNLKFNYTKKTEKARNLKALKIQIQQVDTYPEKIQILKKKIDNLEKRLVDTATNEPNVRVFLGSVSELQKQLNDFGIVVEDYKQNLGLTEHLQLMMEECQFCFEDVSATVIRVGKYSAECKTREAMETLYKQFNKFIESTVPQQEEKFQQIIDLAKQLYGFEEGNKYVEKAVSKYKEILNSVDELCKSLREFKEIQKDEFAGELVTVQKEGNSREECEDKADGKKYQMGSDMLLINSEYVTEKRNNILSPTNTKQERNKLADIPIICPAGEDLVSQDTELSSSAKEDSLQTEFLAEEIPSGDEYECISPDDISLPPLSETPESNLLHSETELEEQRCCSSRSLHASSYSLQMQKTSSDKRLMESSDLLTNSAYADATVTRMESPSAQLEKFCISSTDSGPKVRAGFPLASSLRAVSEASTASCTINAKPAYSTMSEVRKTHLQHLEIHKSMAEMREQLHDSNNCTKTQDRLHALPDAFSGFVFQSDATRSCQRQMVTREEIKSTSEKNSMACLTGQAPNFSQLLSNLTVTEGSPVTLEVEVTGIPEPTLTWYKKGQKVTADEHLKLYQKETKHALFIQKVCDNDAGLYVARAKNSSGTISSSAILHVQVCTMIFKDSGVLDKDVQISWDHQTQRCSLMKFLPKISKQ", "length": 1563, "header": "tr|A0A8V1A0H5-1|A0A8V1AAT3_CHICK Computationally mapped isoform of Coiled-coil domain containing 141 OS=Gallus gallus OX=9031 GN=CCDC141 PE=3 SV=1 CANONICAL=A0A8V1AAT3-1" }, "locus": { "chromosome": "7", "start_pos": 14749460, "end_pos": 14695451, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063875.1", "url": "https://www.ensembl.org/id/ENSGALT00010063875.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039371.1", "url": "https://www.ensembl.org/id/ENSGALP00010039371.1" } ] } }, { "isoform_ac": "A0A8V1A5M4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAT3/entry#A0A8V1A5M4-1", "sequence": { "sequence": "MSNEAGLEQKLSTTTLSSVAVQAGNASIVIAVLKCGKWVKLQLAESTPNLLEIGSNQDETRKLLQDHELLLTKLKALEDKVWDLLHEADKAAEENKEKSQVYDAMAETLGDAWDTLIIMLEKRQALLELTMVFFENALEFAVKIDQVEDFLKNAQEFDNIDNLRELLLQQEHHTKELLEKSLALLNKSHELTEFIEEFKREGPNANTEVIQGAQSSCLKIDSLLELLQDRRRQLDRSLKHQRQGLEQVLQICLWHQQENQVTSWYKKNIRDYIHKQNLGSSLLENEELLKEHKEMEVRLKEWSSTVEQLEAEAVKILLSEDYTEKEHLNLSSQKIHLLRGEVCCHMEERKALLQEANDFFNTAGKALDALENYLKIFNSEGLSLPVLSMKYDELKEEIKGCTASTLQKGQTLINKADSHSSWVIGIQKMMENVNEKEDQLIRQCPHDKELMLKKQQQTSSLEHHLNKVSQSIKKITLMLAVDVEIGSHLSESERILNEHLELANQIKETSCELAEAEGIIKDMKEFEPEQVAAFNSKTDFLNEELKKAERNISTKIEILSTYVAFLKSSLEVNDYIQNLKEFYQAEPLQTSREAENKNTMESVNTKWQKSIEKFFSTENLGRIFLNLVNTVNEGLILKVQKSVQVIEETIINLSKEMKELTDLWAVWNFKINQVKPIKQQCWILEEQLNKTTHGLQILQEALTLASTVDLGSDLCIALEQQKLNQMKPQFQQLNAELEYMMKLLELPSQKGFPMKENSERISELIHLHQMVKSTMTEYDEIFNKALKFHHVKKELECLSKSGELDFPEITVGPEDVHHAKAYLLNAQKKHMHIRQLYKLVINQGVDILSAVQKPNCLNVSVKNLKQELARLECDNINWSSKADKYEEELSQHFQYHIYQEEINELRESFKDLKKKFNNLKFNYTKKTEKARNLKALKIQIQQVDTYPEKIQILKKKIDNLEKRLVDTATNEPNVRVFLGSVSELQKQLNDFGIVVEDYKQNLGLTEHLQLMMEECQFCFEDVSATVIRVGKYSAECKTREAMETLYKQFNKFIESTVPQQEEKFQQIIDLAKQLYGFEEGNKYVEKAVSKYKEILNSVDELCKSLREFKEIQKDEFAGELVTVQKEGNSREECEDKADGKKYQERNKLADIPIICPAGEDLVSQDTELSSSAKEDSLQTEFLAEEIPSGDEYECISPDDISLPPLSETPESNLLHSETELEEQRCCSSRSLHASSYSLQMQKTSSDKRLMESSDLLTNSAYADATVTRMESPSAQLEKFCISSTDSGPKVRAGFPLASSLRAVSEASTASCTINAKPAYSTMSEVRKTHLQHLEIHKSMAEMREQLHDSNNCTKTQDRLHALPDAFSGFVFQSDATRSCQRQMVTREEIKSTSEKNSMACLTGQAPNFSQLLSNLTVTEGSPVTLEVEVTGIPEPTLT", "length": 1438, "header": "tr|A0A8V1A5M4-1|A0A8V1AAT3_CHICK Computationally mapped isoform of Coiled-coil domain containing 141 OS=Gallus gallus OX=9031 GN=CCDC141 PE=3 SV=1 CANONICAL=A0A8V1AAT3-1" }, "locus": { "chromosome": "7", "start_pos": 14742747, "end_pos": 14695451, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063866.1", "url": "https://www.ensembl.org/id/ENSGALT00010063866.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039368.1", "url": "https://www.ensembl.org/id/ENSGALP00010039368.1" } ] } }, { "isoform_ac": "A0A8V1A5M9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAT3/entry#A0A8V1A5M9-1", "sequence": { "sequence": "MVGGGSTFFFFAPSLEKQCGKWVKLQLAESTPNLLEIGSNQDETRKLLQDHELLLTKLKALEDKVWDLLHEADKAAEENKEKSQVYDAMAETLGDAWDTLIIMLEKRQALLELTMVFFENALEFAVKIDQVEDFLKNAQEFDNIDNLRELLLQQEHHTKELLEKSLALLNKSHELTEFIEEFKREGPNANTEVIQGAQSSCLKIDSLLELLQDRRRQLDRSLKHQRQGLEQVLQICLWHQQENQVTSWYKKNIRDYIHKQNLGSSLLENEELLKEHKEMEVRLKEWSSTVEQLEAEAVKILLSEDYTEKEHLNLSSQKIHLLRGEVCCHMEERKALLQEANDFFNTAGKALDALENYLKIFNSEGLSLPVLSMKYDELKEEIKGCTASTLQKGQTLINKADSHSSWVIGIQKMMENVNEKEDQLIRQCPHDKELMLKKQQQTSSLEHHLNKVSQSIKKITLMLAVDVEIGSHLSESERILNEHLELANQIKETSCELAEAEGIIKDMKEFEPEQVAAFNSKTDFLNEELKKAERNISTKIEILSTYVAFLKSSLEVNDYIQNLKEFYQAEPLQTSREAENKNTMESVNTKWQKSIEKFFSTENLGRIFLNLVNTVNEGLILKVQKSVQVIEETIINLSKEMKELTDLWAVWNFKINQVKPIKQQCWILEEQLNKTTHGLQILQEALTLASTVDLGSDLCIALEQQKLNQMKPQFQQLNAELEYMMKLLELPSQKGFPMKENSERISELIHLHQMVKSTMTEYDEIFNKALKFHHVKKELECLSKSGELDFPEITVGPEDVHHAKAYLLNAQKKHMHIRQLYKLVINQGVDILSAVQKPNCLNVSVKNLKQELARLECDNINWSSKADKYEEELSQHFQYHIYQEEINELRESFKDLKKKFNNLKFNYTKKTEKARNLKALKIQIQQVDTYPEKIQILKKKIDNLEKRLVDTATNEPNVRVFLGSVSELQKQLNDFGIVVEDYKQNLGLTEHLQLMMEECQFCFEDVSATVIRVGKYSAECKTREAMETLYKQFNKFIESTVPQQEEKFQQIIDLAKQLYGFEEGNKYVEKAVSKYKEILNSVDELCKSLREFKEIQKDEFAGELVTVQKEGNSREECEDKADGKKYQMGSDMLLINSEYVTEKRNNILSPTNTKQERNKLADIPIICPAGEDLVSQDTELSSSAKEDSLQTEFLAEEIPSGDEYECISPDDISLPPLSETPESNLLHSETELEEQRCCSSRSLHASSYSLQMQKTSSDKRLMESSDLLTNSAYADATVTRMESPSAQLEKFCISSTDSGPKVRAGFPLASSLRAVSEASTASCTINAKPAYSTMSEVRKTHLQHLEIHKSMAEMREQLHDSNNCTKTQDRLHALPDAFSGFVFQSDATRSCQRQMVTREEIKSTSEKNSMACLTGQAPNFSQLLSNLTVTEGSPVTLEVEVTGIPEPTLTWWVAYNEKK", "length": 1459, "header": "tr|A0A8V1A5M9-1|A0A8V1AAT3_CHICK Computationally mapped isoform of Coiled-coil domain containing 141 OS=Gallus gallus OX=9031 GN=CCDC141 PE=3 SV=1 CANONICAL=A0A8V1AAT3-1" }, "locus": { "chromosome": "7", "start_pos": 14742774, "end_pos": 14687001, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063880.1", "url": "https://www.ensembl.org/id/ENSGALT00010063880.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039373.1", "url": "https://www.ensembl.org/id/ENSGALP00010039373.1" } ] } }, { "isoform_ac": "A0A8V1A5N3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAT3/entry#A0A8V1A5N3-1", "sequence": { "sequence": "MSNEAGLEQKLSTTTLSSVAVQAGNASIVIAVLKCGKWVKLQLAESTPNLLEIGSNQDETRKLLQDHELLLTKLKALEDKVWDLLHEADKAAEENKEKSQVYDAMAETLGDAWDTLIIMLEKRQALLELTMVFFENALEFAVKIDQVEDFLKNAQEFDNIDNLRELLLQQEHHTKELLEKSLALLNKSHELTEFIEEFKREGPNANTEVIQGAQSSCLKIDSLLELLQDRRRQLDRSLKHQRQGLEQVLQICLWHQQENQVTSWYKKNIRDYIHKQNLGSSLLENEELLKEHKEMEVRLKEWSSTVEQLEAEAVKILLSEDYTEKEHLNLSSQKIHLLRGEVCCHMEERKALLQEANDFFNTAGKALDALENYLKIFNSEGLSLPVLSMKYDELKEEIKGCTASTLQKGQTLINKADSHSSWVIGIQKMMENVNEKEDQLIRQCPHDKELMLKKQQQTSSLEHHLNKVSQSIKKITLMLAVDVEIGSHLSESERILNEHLELANQIKETSCELAEAEGIIKDMKEFEPEQVAAFNSKTDFLNEELKKAERNISTKIEILSTYVAFLKSSLEVNDYIQNLKEFYQAEPLQTSREAENKNTMESVNTKWQKSIEKFFSTENLGRIFLNLVNTVNEGLILKVQKSVQVIEETIINLSKEMKELTDLWAVWNFKINQVKPIKQQCWILEEQLNKTTHGLQILQEALTLASTVDLGSDLCIALEQQKLNQMKPQFQQLNAELEYMMKLLELPSQKGFPMKENSERISELIHLHQMVKSTMTEYDEIFNKALKFHHVKKELECLSKSGELDFPEITVGPEDVHHAKAYLLNAQKKHMHIRQLYKLVINQGVDILSAVQKPNCLNVSVKNLKQELARLECDNINWSSKADKYEEELSQHFQYHIYQEEINELRESFKDLKKKFNNLKFNYTKKTEKARNLKALKIQIQQVDTYPEKIQILKKKIDNLEKRLVDTATNEPNVRVFLGSVSELQKQLNDFGIVVEDYKQNLGLTEHLQLMMEECQFCFEDVSATVIRVGKYSAECKTREAMETLYKQFNKFIESTVPQQEEKFQQIIDLAKQLYGFEEGNKYVEKAVSKYKEILNSVDELCKSLREFKEIQKDEFAGELVTVQKEGNSREECEDKADGKKYQMGSDMLLINSEYVTEKRNNILSPTNTKQERNKLADIPIICPAGEDLVSQDTELSSSAKEDSLQTEFLAEEIPSGDEYEYATRSCQRQMVTREEIKSTSEKNSMACLTGQAPNFSQLLSNLTVTEGSPVTLEVEVTGIPEPTLTWYKKGQKVTADEHLKLYQKETKHALFIQKVCDNDAGLYVARAKNSSGTISSSAILHVQVQGKQPNFVQKFGHTTLQEGEDLILHCTVHGKPKPHVCWTKDDIQVVAGDVSTEKLGDNYYLLKRNVALADTGKYICVASNEVGKAHCSATVTVIEKNKNPEISTVTQAKSEWENGCFSEKGNVTAAELARAQDMCCVRGQRPVPRHLPVRFKEKLWLQGVYLELVRPPDISFSLEHVPGLLQPTAKDQKVDCT", "length": 1538, "header": "tr|A0A8V1A5N3-1|A0A8V1AAT3_CHICK Computationally mapped isoform of Coiled-coil domain containing 141 OS=Gallus gallus OX=9031 GN=CCDC141 PE=3 SV=1 CANONICAL=A0A8V1AAT3-1" }, "locus": { "chromosome": "7", "start_pos": 14752845, "end_pos": 14695451, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063896.1", "url": "https://www.ensembl.org/id/ENSGALT00010063896.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039378.1", "url": "https://www.ensembl.org/id/ENSGALP00010039378.1" } ] } }, { "isoform_ac": "A0A8V1A816-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAT3/entry#A0A8V1A816-1", "sequence": { "sequence": "MSNEAGLEQKLSTTTLSSVAVQAGNASIVIAVLKCGKWVKLQLAESTPNLLEIGSNQDETRKLLQDHELLLTKLKALEDKVWDLLHEADKAAEENKEKSQVYDAMAETLGDAWDTLIIMLEKRQALLELTMVFFENALEFAVKIDQVEDFLKNAQEFDNIDNLRELLLQQEHHTKELLEKSLALLNKSHELTEFIEEFKREGPNANTEVIQGAQSSCLKIDSLLELLQDRRRQLDRSLKHQRQGLEQVLQICLWHQQENQVTSWYKKNIRDYIHKQNLGSSLLENEELLKEHKEMEVRLKEWSSTVEQLEAEAVKILLSEDYTEKEHLNLSSQKIHLLRGEVCCHMEERKALLQEANDFFNTAGKALDALENYLKIFNSEGLSLPVLSMKYDELKEEIKGCTASTLQKGQTLINKADSHSSWVIGIQKMMENVNEKEDQLIRQCPHDKELMLKKQQQTSSLEHHLNKVSQSIKKITLMLAVDVEIGSHLSESERILNEHLELANQIKETSCELAEAEGIIKDMKEFEPEQVAAFNSKTDFLNEELKKAERNISTKIEILSTYVAFLKSSLEVNDYIQNLKEFYQAEPLQTSREAENKNTMESVNTKWQKSIEKFFSTENLGRIFLNLVNTVNEGLILKVQKSVQVIEETIINLSKEMKELTDLWAVWNFKINQVKPIKQQCWILEEQLNKTTHGLQILQEALTLASTVDLGSDLCIALEQQKLNQMKPQFQQLNAELEYMMKLLELPSQKGFPMKENSERISELIHLHQMVKSTMTEYDEIFNKALKFHHVKKELECLSKSGELDFPEITVGPEDVHHAKAYLLNAQKKHMHIRQLYKLVINQGVDILSAVQKPNCLNVSVKNLKQELARLECDNINWSSKADKYEEELSQHFQYHIYQEEINELRESFKDLKKKFNNLKFNYTKKTEKARNLKALKIQIQQVDTYPEKIQILKKKIDNLEKRLVDTATNEPNVRVFLGSVSELQKQLNDFGIVVEDYKQNLGLTEHLQLMMEECQFCFEDVSATVIRVGKYSAECKTREAMETLYKQFNKFIESTVPQQEEKFQQIIDLAKQLYGFEEGNKYVEKAVSKYKEILNSVDELCKSLREFKEIQKDEFAGELVTVQKEGNSREECEDKADGKKYQMGSDMLLINSEYVTEKRNNILSPTNTKQERNKLADIPIICPAGEDLVSQDTELSSSAKEDSLQTEFLAEEIPSGDEYECISPDDISLPPLSETPESNLLHSETELEEQRCCSSRSLHASSYSLQMQKTSSDKRLMESSDLLTNSAYADATVTRMESPSAQLEKFCISSTDSGPKVRAGFPLASSLRAVSEASTASCTINAKPAYSTMSEVRKTHLQHLEIHKSMAEMREQLHDSNNCTKTQDRLHALPDAFSGFVFQSDATRSCQRQMVTREEIKSTSEKNSMACLTGQAPNFSQLLSNLTVTEGSPVTLEVEVTGIPEPTLTWWVAYNEKK", "length": 1475, "header": "tr|A0A8V1A816-1|A0A8V1AAT3_CHICK Computationally mapped isoform of Coiled-coil domain containing 141 OS=Gallus gallus OX=9031 GN=CCDC141 PE=3 SV=1 CANONICAL=A0A8V1AAT3-1" }, "locus": { "chromosome": "7", "start_pos": 14742774, "end_pos": 14695451, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063871.1", "url": "https://www.ensembl.org/id/ENSGALT00010063871.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039370.1", "url": "https://www.ensembl.org/id/ENSGALP00010039370.1" } ] } }, { "isoform_ac": "A0A8V1AAT3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAT3/entry#A0A8V1AAT3-1", "sequence": { "sequence": "MSNEAGLEQKLSTTTLSSVAVQAGNASIVIAVLKCGKWVKLQLAESTPNLLEIGSNQDETRKLLQDHELLLTKLKALEDKVWDLLHEADKAAEENKEKSQVYDAMAETLGDAWDTLIIMLEKRQALLELTMVFFENALEFAVKIDQVEDFLKNAQEFDNIDNLRELLLQQEHHTKELLEKSLALLNKSHELTEFIEEFKREGPNANTEVIQGAQSSCLKIDSLLELLQDRRRQLDRSLKHQRQGLEQVLQICLWHQQENQVTSWYKKNIRDYIHKQNLGSSLLENEELLKEHKEMEVRLKEWSSTVEQLEAEAVKILLSEDYTEKEHLNLSSQKIHLLRGEVCCHMEERKALLQEANDFFNTAGKALDALENYLKIFNSEGLSLPVLSMKYDELKEEIKGCTASTLQKGQTLINKADSHSSWVIGIQKMMENVNEKEDQLIRQCPHDKELMLKKQQQTSSLEHHLNKVSQSIKKITLMLAVDVEIGSHLSESERILNEHLELANQIKETSCELAEAEGIIKDMKEFEPEQVAAFNSKTDFLNEELKKAERNISTKIEILSTYVAFLKSSLEVNDYIQNLKEFYQAEPLQTSREAENKNTMESVNTKWQKSIEKFFSTENLGRIFLNLVNTVNEGLILKVQKSVQVIEETIINLSKEMKELTDLWAVWNFKINQVKPIKQQCWILEEQLNKTTHGLQILQEALTLASTVDLGSDLCIALEQQKLNQMKPQFQQLNAELEYMMKLLELPSQKGFPMKENSERISELIHLHQMVKSTMTEYDEIFNKALKFHHVKKELECLSKSGELDFPEITVGPEDVHHAKAYLLNAQKKHMHIRQLYKLVINQGVDILSAVQKPNCLNVSVKNLKQELARLECDNINWSSKADKYEEELSQHFQYHIYQEEINELRESFKDLKKKFNNLKFNYTKKTEKARNLKALKIQIQQVDTYPEKIQILKKKIDNLEKRLVDTATNEPNVRVFLGSVSELQKQLNDFGIVVEDYKQNLGLTEHLQLMMEECQFCFEDVSATVIRVGKYSAECKTREAMETLYKQFNKFIESTVPQQEEKFQQIIDLAKQLYGFEEGNKYVEKAVSKYKEILNSVDELCKSLREFKEIQKDEFAGELVTVQKEGNSREECEDKADGKKYQMGSDMLLINSEYVTEKRNNILSPTNTKQERNKLADIPIICPAGEDLVSQDTELSSSAKEDSLQTEFLAEEIPSGDEYECISPDDISLPPLSETPESNLLHSETELEEQRCCSSRSLHASSYSLQMQKTSSDKRLMESSDLLTNSAYADATVTRMESPSAQLEKFCISSTDSGPKVRAGFPLASSLRAVSEASTASCTINAKPAYSTMSEVRKTHLQHLEIHKSMAEMREQLHDSNNCTKTQDRLHALPDAFSGFVFQSDATRSCQRQMVTREEIKSTSEKNSMACLTGQAPNFSQLLSNLTVTEGSPVTLEVEVTGIPEPTLTWYKKGQKVTADEHLKLYQKETKHALFIQKVCDNDAGLYVARAKNSSGTISSSAILHVQVQGKQPNFVQKFGHTTLQEGEDLILHCTVHGKPKPHVCWTKDDIQVVAGDVSTEKLGDNYYLLKRNVALADTGKYICVASNEVGKAHCSATVTVIEKNKNPEISTVTQAKSEWENGCFSEKGNVTAAELARAQDMCCVRGQRPVPRHLPVRFKEKLWLQGVYLELVRPPDISFSLEHVPGLLQPTAKDQKVDCT", "length": 1718, "header": "tr|A0A8V1AAT3-1|A0A8V1AAT3_CHICK Isoform 1 of Coiled-coil domain containing 141 OS=Gallus gallus OX=9031 GN=CCDC141 PE=3 SV=1 CANONICAL=A0A8V1AAT3-1" }, "locus": { "chromosome": "7", "start_pos": 14752845, "end_pos": 14695451, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063884.1", "url": "https://www.ensembl.org/id/ENSGALT00010063884.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039374.1", "url": "https://www.ensembl.org/id/ENSGALP00010039374.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1N677-1", "protein_name": "Coiled-coil domain-containing protein 141", "gene_name": "CCDC141", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSSQESPAVEFSTTTVSSVAVQAGDSKIVIAVIKCGKWIQLQLAESQPNLLEIGSNQDETKKLLHDHELLLTKLKALEDRVWELLQEADKTAEENKDQSQVYDAMAKTLGEAWASLVSMLERRRELLRLTSEFFENALEFAIKIDQAEDFLQNTQEFESAESLKSLLQLHELHTKELLERSLALLNKSQELTDFIEKIKSDGPNVSAEMIQGAQNSCLKIDSLLELLQDRRRQLDKYLKQQQQELSQVLQMCQWDQQESQVTCWFQKTIRDLEEQGLGTSLSDNEELIRKHEELIIKAKEWNAVVETLKNEALGLLLSKEHVQSEHLQLSNQKLNQLQEEFGQLMEERKSWLKKANEFFNSANKAFDALGRVEAYLKLLKSEGLSLPVLAVKHEELHREIKDCTADALQKGQALISQLASCSSRVTGVCEIMGCLRRRVEHLTEQCSAHEEFALKRQQLTASVEGHLREVEMSIQKISTILSNAMDVGSSLSESEKILSKYLELDKQAKETSHELEAAAKLLTEKHDFELDELASLSSKAKRLEEELNIFGQSINSRSQVLQTYVAFLKSSEEVEKQCQGLKEFYQTDILRKEEGGAEAKHWSDSVEKQWQLFLKRSFLTHDLGLEFLNLINMAKENEILNVKNEVHVMENTMESQKAEREELSRLRTAWQLKAAASKPVKQQWAAFKEQLRKTMHNLKLLQEALMPVSALDLGGSLQTILALRKKWNEMKPQFQQLNDEVQYIIRESEELNGKGAPVKEKSQQLKDLIHFHQSLKQRIQDYEDILYKIIQFHQVREELGRLLKSRELEFPEQAEETNDAHDAQVLLRRSRAKQAHVDHLHDLALSLGVDVISSVQQPNCSNVSAKNLQQQLDMLEGDCLTWRAQTEDHERALTRSLEFCITRDEIGELKESFKEIKKKFNNLKFNYTKKNEKARNLKALKYQIQQVDIYAEKLQALKRKMEKVENKTSFLNYPNNKVNILLEAMRDLQKHVDEFDKVVTDYRKNLDLTEHLQELIEECHFWYEDASATVVRVGKYSTECKTKEAVEILHQQFKKFITPSVPQQEERIQEISDLAQRLYGFEEGQKYAEKIVAKHKEVLESVTELCSSLTELEEKLKQGDVLKLNLNLEDFHDDCIDLLKEPARNKQTIFNDGSNKEQAQPAAILAVNGARKCQLPQGVKQLVPGKESVQGLLLPVDVLSGAEHECVSSDDISLPPVSGSPDSLLAPSDMELEAPVSPFPRHHLSGHQMQTGASCPGEAPESGFPPPAAFADACNDKRETFSSHFEKPSPQVQAEPPLTSQGFLEKSTAFHKISAQLPDSMCSEVHDRASQQHPQAQGHLLETPEKMHADNNVTKTRNRLHASQDAFSGLGFQPGPSQACQRQMVPREEIISIPAKNSMVSLAGQAPNFSRLLSNVTVVEGSPVTLEVEVTGFPEPTLTWYKKGQKLSADGRLQVLHKETRHLVFIPKVCEADAGLYVAWAQNPSGILSSSVILHVTGNRKPPIRGINWVMLCVIYVTVSLMYWLLTQ", "length": 1528 }, "evidence": [ { "id": "A0A8V1AAT3", "url": "https://omabrowser.org/oma/group/A0A8V1AAT3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "D3ZEY0-1", "protein_name": "Coiled-coil domain-containing protein 141", "gene_name": "Ccdc141", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSCKESPHVGVSTTTVSSVAVQAGDSKIVIAVVKCGKWVRLQLAEAQPNLLEIGSSQDETRKLLHDHELLLAKLKALEDRVWGLLQEADRTAEANKEQSEVYDAMAQTLGEAWATLVSMLERRRELLGLTSEFFQSALEFAIKIDQAEDFLQNPHEFESAEALQSLLLLHDRHAKELLERSLVLLNKSQQLTDFIEKFKCDGSPVNSELIQGAQSSCLKIDSLLELLQDRRRQLDKHLQQQRQELSQVLQLCLWDQQESQVSCWFQKTIRDLQEQSLGSSLSDNKELIRKHEDLTIKAKEWDLAMEKLKSQALGILLSKDLTEKEHLQLSNQKLNRLQEEFGRLMVDRKAWLTMAHDFFTSANEAFDVLGKVEDYLKLLKSEGLSLPALAAKHEELHREIKDSTAAALQKGRTLISQVDSCRAQVTGIHETMGRIQKRVDRLSQQCTAHQEFALKKQQLATSVDDYLRKVEMSVQEMRLVLATTLDVGSSPSESEKILNKYLELDIQAKETAHALEAAAKITTEKNELELNEVALLPFKVKRLEEELSTLSRSVSYRSQVLQTYIAFRKSSEEVEEQLQSLKEFYLTESPWEDEDDAVVTCQSNSAERKWQLFLKKSFLTQDLSLEFLNLISMAKENEILNVKKEMHIVENVMEKQTNGREELSRLRMAWHLKAMEGKPVKERWETFKEKLKKTTHNVKLLHEVLMPVSALDLGGNLQSMSDLRRRWIAMQPQLQQLHEDVQQIMKEWEVLSGQGVPLKEKAEQLKDLIHLHQRQRERIQEYEEILYKTVQFHQVKEELTHLIKPRELELLAQPMELEGSKEVLMQLGRSQGRRAHVDHLHRLALSLGVDIISSVQRPNCSNISAKSLQQQLEALELDSRDWSAKAKEYEQVLACSLEYCTTREEINELKESFKDIKKKFNNLKFNYSKKNEKSRNLKTLQYQIQQVETYADKIQALRKKMEKVNKKISDSVLSYPSNKANTLVEAMEDLKKHVDDFDKVVTDYKMNLDLTEHLQEVIEECNFWYEDASATVVRVGKYSMECQTREAVDILHRQFQKFVTPSVPQQEERIQEVVSLAQRLYGLEEGQKYAEKIVTRHKEILESITELCGSLVELKEKLMQGDVPKVNSNLEDFHGNSIDLLKEPGRDEQTTFSEERSEGQAQGADVSAINGTREDGLPVGLRQSFDKEDSAQGLTLPEDTLSGEDSECISSDDISLPPLPVTPESPLAPSDMEVEEPASSSALALHISGYRMRTGTGGLGKAPESVLPPPTAFTDGYHNKKDTFTSHFERPYPQFKAEPLLTSRGSGEMSTKLHVNVKCPARMPREVHDKALPPSSQAQEISLGTQEKVHADSNVTKTQDRLHAALDVSPGLSSQSDTSRSHQRQVGPQGDRKNSSAEKSVVSLAGQAPHFSRLLSNVTVTEGSPVTLEVEVTGFPEPTLTWFKKGQKLCADGHLQVLHKDTKHSVFIPKVCEADAGLYVAQAQNSSGTLSSKAILHVTGNHGPPITRINWIVLCIIYVSVSVIYWLLTQ", "length": 1530 }, "evidence": [ { "id": "A0A8V1AAT3", "url": "https://omabrowser.org/oma/group/A0A8V1AAT3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E9Q8Q6-1", "protein_name": "Coiled-coil domain-containing protein 141", "gene_name": "Ccdc141", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSCKESPHVGASTTTVSSVAVHAGDSKIVIAVVKCGKWVRLQLAESQPNLLEIGSSQDETKKLLHDHELLLAKLKALEDRVWELLREADRTAEANKAQSQVYDAMAQTLGEAWATLVSMLERRRELLGLTSEFFQSALEFAIKIDQAEAFLQNPHEFESTEALQSLLLLHDRHAKELLERSLDLLNKSQQLTDFIEKFKCEGSTMNSELIQGAQSSCLKIDSLLELLQDRRRQLDKYLQQQRQELSQVLQLCLWDQQENQVSSWFQKAIRDLQEQSLGASLSDNRELICKHEDLIVKAKEWDSAVEKLKSQALGILLSKDLAGKEHLQLSNQKLNRLQEEFGRLMVERKAWLSMANDFFTSANKSFDVLGKVEAYLKLLKSEGLSLPVLAAKHEELHREIKDSTATALQKGRTLISQVDSCRSRVTGIHEMMGYIQNRVDCLTEQCTAHEEFARKRQQLATSVDDYLRKVEMSIQEIRPILATTLDVASSPSESEKILNKYLELDIQVKETAHALEAAAKIMTEKNELELNEVALLPLKVKWLEEELSTLGRSISCRSRILQTYVAFRKSSEEAEEQLQSLKEFYLTEIPWKDEDDAVVKCQSNSAERKWQLFLKKSFLTQDLSLEFLNLINMAKENEILNVKNEMHIMENIMEKQTNGREELSHLRVAWYLKAIEGKPAREQWEMFKEKLTKTTHSVKLLHEVLMPVSALDLGGSLQSTSDLRRRWIAMKPQLQQLHEDVQQITKEWEVLSSQGAPLKEKAEQLKDLVHLHRRQRERIQEYEEILYKTVQFHQVKEELVHLIKPRELELLAQPMELASSEEVQMQLGRSQERRAHVDHLHQLALTLGVDIISSVQQPNCSNISAKNLQQQLEALELESRSWSAQAKEHERVLSCSLEYCTARDEISELKESFKDIKKKFNNLKFNYSKKNEKSRNLKTLQYQIQQVDTYAEKIQALRKKMEKVNNKTSDSFLSYPSNKANMLSEAMEDLKKNVDDFDKVVTDYKMNLDLTEHLQEVIEECNFWYEDASATVVRVGKYSMECQTREAVDILHRQFNKFITPSVPQQEERIQEVIDLAQRLYGLEEGQKYAEKIVTRHKEILESITELCGSLVELKEKLMQGEVPKMNSDLEDFHDNCIDLLKGPGKDDQKTFSEERNEGQVQGADVLAVNGTREDGLPMDLRRTSSDKEDSAQGLILPEDTLSGEESECISSDDISLPPLPVSPESPLAPSDMEVEELTSSSALALHISGYRMHPGTGGLGKAQESALPSPIAFADGGHSKKDTFTSHFERPYPQLKAESSLASRGSAEMSTKLHINVKCPASMPHEVHDKALQQCSQARESTLEMQEKVHADSNVTKTQDRLHAALDVSPGLGSQPDTSESHQRRVGPQGNKKNSSAENSVVSLAGQAPHFSRLLSNVTVMEGSPVTLEVEVTGFPEPTLTWFKKGQKLCADGHLQVLHKDTKHSVFIPKVCEADAGLYVAQAQNSSGTLSSKAILHVTGNHGPPITRLNWIMLCIIYVSVSVIYWLLTR", "length": 1531 }, "evidence": [ { "id": "A0A8V1AAT3", "url": "https://omabrowser.org/oma/group/A0A8V1AAT3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6ZP82-2", "protein_name": "Coiled-coil domain-containing protein 141", "gene_name": "CCDC141", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSSQGSPSVALSTTTVSSVAVQAGDSKIVIAVIKCGKWVQLQLAESQPNLLEIGSSQDETKKLLHDHELLLAKLKALEDRVWELLQEADKTAEENKDQSQVYDAMAETLGEAWAALVSMLERRTELLRLTSEFFENALEFAIKIDQAEDFLQNTHEFESAESLKSLLQLHEHHTKELLERSLALLNKSQQLTDFIEKFKCEGPNVNPELTQGAHSSCLKVDRLLELLQDRRRQLDKYLKQQWQELSQVLQICQWDQQENQVTCWFQKTIRNLQEQSLGSSLSDNEDRIHKQEELIIKAKEWNSAVEKLKSEALRILLSKDYVEKEHLQLSHQKLSQLQEEFGQLMVERNTWLKKANEFFNSANKAFDVLGRVEAYLKLLKSEGLSLAVLAVRHEELHRKIKDCTTDALQKGQTLISQVDSCSSQVSGIHEMMGCIKRRVDHLTEQCSAHKEYALKKQQLTASVEGYLRKVEMSIQKISPVLSNAMDVGSTRSESEKILNKYLELDIQAKETSHELEAAAKTMMEKNEFVSDEMVSLSSKARWLAEELNLFGQSIDYRSQVLQTYVAFLKSSEEVEMQFQSLKEFYETEIPQKEQDDAKAKHCSDSAEKQWQLFLKKSFITQDLGLEFLNLINMAKENEILDVKNEVYLMKNTMENQKAEREELSLLRLAWQLKATESKPGKQQWAAFKEQLKKTSHNLKLLQEALMPVSALDLGGSLQFILDLRQKWNDMKPQFQQLNDEVQYIMKESEELTGRGAPVKEKSQQLKDLIHFHQKQKERIQDYEDILYKVVQFHQVKEELGRLIKSRELEFVEQPKELGDAHDVQIHLRCSQEKQARVDHLHRLALSLGVDIISSVQRPHCSNVSAKNLQQQLELLEEDSMKWRAKAEEYGRTLSRSVEYCAMRDEINELKDSFKDIKKKFNNLKFNYTKKNEKSRNLKALKYQIQQVDMYAEKMQALKRKMEKVSNKTSDSFLNYPSDKVNVLLEVMKDLQKHVDDFDKVVTDYKKNLDLTEHFQEVIEECHFWYEDASATVVRVGKYSTECKTKEAVKILHQQFNKFIAPSVPQQEERIQEATDLAQHLYGLEEGQKYIEKIVTKHKEVLESVTELCESLTELEEKLKQGDVLKMNPNLEDFHYDYIDLLKEPAKNKQTIFNEERNKGQVQVADLLGINGTGEERLPQDLKVSTDKEGGVQDLLLPEDMLSGEEYECVSPDDISLPPLPGSPESPLAPSDMEVEEPVSSSLSLHISSYGVQAGTSSPGDAQESVLPPPVAFADACNDKRETFSSHFERPYLQFKAEPPLTSRGFVEKSTALHRISAEHPESMMSEVHERALQQHPQAQGGLLETREKMHADNNFTKTQDRLHASSDAFSGLRFQSGTSRGYQRQMVPREEIKSTSAKSSVVSLADQAPNFSRLLSNVTVMEGSPVTLEVEVTGFPEPTLTWYKKGQKLSADGHLQVLHKETRHSVFIPKVCKADAGLYVARAQNSSGALSSNVILHVTGNCRLPITRVNWITLCVVYVSVSLMYWLLTQ", "length": 1530 }, "evidence": [ { "id": "A0A8V1AAT3", "url": "https://omabrowser.org/oma/group/A0A8V1AAT3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAT3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAT3" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAT3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAT3" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAT3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAT3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "brain development", "id": "GO:0007420", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007420", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAT3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAT3" } ], "pmid": "" }, { "name": "regulation of synapse assembly", "id": "GO:0051963", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051963", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAT3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAT3" } ], "pmid": "" }, { "name": "heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules", "id": "GO:0007157", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007157", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAT3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAT3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1379, "end_pos": 1381, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1435, "end_pos": 1437, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1442, "end_pos": 1444, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1510, "end_pos": 1512, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1647, "end_pos": 1649, "annotation": "n_glycosylation_sequon" }, { "start_pos": 186, "end_pos": 188, "annotation": "n_glycosylation_sequon" }, { "start_pos": 25, "end_pos": 27, "annotation": "n_glycosylation_sequon" }, { "start_pos": 329, "end_pos": 331, "annotation": "n_glycosylation_sequon" }, { "start_pos": 551, "end_pos": 553, "annotation": "n_glycosylation_sequon" }, { "start_pos": 652, "end_pos": 654, "annotation": "n_glycosylation_sequon" }, { "start_pos": 689, "end_pos": 691, "annotation": "n_glycosylation_sequon" }, { "start_pos": 858, "end_pos": 860, "annotation": "n_glycosylation_sequon" }, { "start_pos": 877, "end_pos": 879, "annotation": "n_glycosylation_sequon" }, { "start_pos": 922, "end_pos": 924, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AAT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAT3" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 1434, "end_pos": 1522, "start_aa": "Pro", "end_aa": "His", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1379, "end_pos": 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}, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ 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"count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AD28-1", "uniprot_ac": "A0A8V1AD28", "uniprot_id": "A0A8V1AD28_CHICK", "mass": { "chemical_mass": 219253.0, "monoisotopic_mass": 219253.0 }, "refseq": {}, "gene_names": [ { "name": "NAV1", "type": "recommended", "evidence": [ { "id": "A0A8V1AD28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD28" } ] } ], "protein_names": [ { "name": "Neuron navigator 1", "type": 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] }, { "id": "A0A8V1A5P2", "url": "https://www.orthodb.org/?gene=A0A8V1A5P2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A842", "url": "https://www.orthodb.org/?gene=A0A8V1A842", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AAW0", "url": "https://www.orthodb.org/?gene=A0A8V1AAW0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AD18", "url": "https://www.orthodb.org/?gene=A0A8V1AD18", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AD28", "url": "https://www.orthodb.org/?gene=A0A8V1AD28", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12784", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12784", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12784:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12784:SF3", "database": 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"UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A842-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A842-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AAW0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAW0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AAW0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAW0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AD18", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD18", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AD18-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD18-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AD28", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD28", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AD28-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD28-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNGTANLAPTARGHFTSAIPVPRSTTPNKPPAAAPPARHSTSGPPASHRATSPRPAALLGPKSLKPRPRASGHEATESPGVPPHGGQRTPVLPGKGLGGSQVECSLRGAGAHRPLGMAVEDGPNASPMSRSPMFGSGAISFSSASPQSRPVTATVAPFQYRLQEDREQNATSLCDSTPAEVPDPKSRAMTPGGLNDCSAGMLGSNLKSLPDVELGEEGAAELRGYRRGPDGGGAVMPKRAKAAAAAAGGPRGAELRVFKASSAEGRLPAGSNLRKQKSLTNLAFLTDAEKKRQLYEPRWSDDMAKGTGSTAVAAGGRGGGGGPRGREAPAMSRSLSRSEHSLLPPRPAGPQKPPPAAGKPSRIPRGPYAEVKPLSKAPEAGGGGGGGGGGKCDDELLGGKGPAAAGAEEKAYLKVDPELVVTVLGDLEQLLFSQMLDPESQRKRTVQNVLDLRQNLEETMSSLRGSQVSHSSLEMTCYDSDEANPRSVSSLSNRSSPLSWRYGQSSPRLQAGDAPSVGGGCRSEGTPGWYMHGERAHYSHTMPMRSPSKLSHISRLELVEALDSDDVELKSGYMSDSDLMGKTLTEDDDITTGWDESSSISSGLSDASDNLSSEEFNASSSLNSLPSTPTASRRNSAIALRTDSEKRSLAESGLSWYGEADDKAPKKLDYDSSSLKMEHGSSKWRREPTESCEEGSKGGELKKPVSLGTPGSLKKGKTPPVAVTSPITHTAQSTLKVAGKPETKATDKSKLSVKNTGLQRSSSDAGRDRVGDAKKPPSGLTRPLASSSFGYKKPAPATGTATVMQAGGSATLGKIQKSSGIPVKPVSGRKTSLDVSNTAEPGFLAPGARTNIQYRSLPRPAKSSSMSVTGGRGANRPVSSSIDPSLLSTKQASITVSRLKEPSKISAGRGTPAPVNQTDREKEKAKAKAVALDSECVTLKSIGSPESTPKAQANLPPAAKVAELPPTPLRAAAKTYVKPPSLANLDKVNSNSLDLPSSSELHPPHAAKLQDLHPAGGHLTPCFSPSPAPILNINSASFSQGLELMGGFSVPKEGRMYPKLSGLHRSMESLQMPMSLPSAFSGGSTATPSPAAVPPASTEEEEEAGELGWSGSPRLAHLDSTNRDRNTLPKKGLRYQLHSQEEAKERRHSHTIGGLPEADDQPELPSPPALPMALVGKGPLTSIVSPTATTTPRITRSNSIPTHDSTFELYSTSQMGSTLSLADKPKGMIRSGSFRDPVDDVHGSVLSLASSASSTYSSAEEKMQSEQIRKLRRELESSQEKVATLTSQLSANANLVAAFEQSLVSMTSRLRHLAETAEEKDTELLDLRETIDFLKKKNSEAQAVIQGALNGTDVAPKELRIKRQNSSDSISSLNSITSHSSISSSKDADAKKKKKKSWLRSSFNKAFSIKKGPKSASSYSDIEEIATPDSSAPSSPKLQHGSTETASPSIKSSTSSSVGIDTAELFQAHSEGEPEKKEVSELRSELWEKEMKLTDIRLEALNSAHQLEQLRETMHNMQLEVDLLKAENDRLKVAPGPSAVPGSIPGHITSTSASSSPRRSLGLSLGHAFSPSPGDADMSPMDAVSAGTQKDELTLRIVVRMPPQHIIKGDLKQQEFFLGWTKVSGKVDWKMLDEAVCQVFKDYITKMDPASTLGLSTESVYGYSISHIKRVLDTEPPELPLCRRGMSSIVVTLKGLKEKCVDSLVFETLIPKPMMQHYISLLLKHRRLILSGPSGTGKTYLTNRLAEYLVERSGRDVTEGIVSTFNMHQQSCKDLQLYLSNLANQIDRETGTADVPLVILLDDLSEAGSISELVNGALTCKYHKCPYIIGTTNQPVKMTPNHGLHLSFRMLTFSNNVEPANGFLVRYLRRKLLESDTDVNANKEELLRVLDWVPKLWYHLHTFLEKHSTSDFLIGPCFFLSCPIGIEDFRTWFIDLWNNSIIPYLQEGAKDGLKVHGQKAAWEDPVEWVRDTLPWPSAQQDQSKLYHLPPPTIGPHSTVSPPEERTVKDTTPSSLDADPLMAMLLKLQEAANYIESPDRETMVDPDLQSTL", "length": 2051, "header": "tr|A0A8V1AD28-1|A0A8V1AD28_CHICK Isoform 1 of Neuron navigator 1 OS=Gallus gallus OX=9031 GN=NAV1 PE=3 SV=1 CANONICAL=A0A8V1AD28-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A0J5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD28/entry#A0A8V1A0J5-1", "sequence": { "sequence": "MNGTANLAPTARGHFTSAIPVPRSTTPNKPPAAAPPARHSTSGPPASHRATSPRPAALLGPKSLKPRPRASGHEATESPGVPPHGGQRTPVLPGKGLGGSQVECSLRGAGAHRPLGMAVEDGPNASPMSRSPMFGSGAISFSSASPQSRPVTATVAPFQYRLQEDREQNATSLCDSTPAEVPDPKSRAMNPESQRKRTVQNVLDLRQNLEETMSSLRGSQVSHSSLEMTCYDSDEANPRSVSSLSNRSSPLSWRYGQSSPRLQAGDAPSVGGGCRSEGTPGWYMHGERAHYSHTMPMRSPSKLSHISRLELVEALDSDDVELKSGYMSDSDLMGKTLTEDDDITTGWDESSSISSGLSDASDNLSSEEFNASSSLNSLPSTPTASRRNSAIALRTDSEKRSLAESGLSWYGEADDKAPKKLDYDSSSLKMEHGSSKWRREPTESCEEGSKGGELKKPVSLGTPGSLKKGKTPPVAVTSPITHTAQSTLKVAGKPETKATDKSKLSVKNTGLQRSSSDAGRDRVGDAKKPPSGLTRPLASSSFGYKKPAPATGTATVMQAGGSATLGKIQKSSGIPVKPVSGRKTSLDVSNTAEPGFLAPGARTNIQYRSLPRPAKSSSMSVTGGRGANRPVSSSIDPSLLSTKQASITVSRLKEPSKISAGRGTPAPVNQTDREKEKAKAKAVALDSECVTLKSIGSPESTPKAQANLPPAAKVAELPPTPLRAAAKTYVKPPSLANLDKVNSNSLDLPSSSELHPPHAAKLQDLHPAGGHLTPCFSPSPAPILNINSASFSQGLELMGGFSVPKEGRMYPKLSGLHRSMESLQMPMSLPSAFSGGSTATPSPAAVPPASTEEEEEAGELGWSGSPRLAHLDSTNRDRNTLPKKGLRYQLHSQEEAKERRHSHTIGGLPEADDQPELPSPPALPMALVGKGPLTSIVSPTATTTPRITRSNSIPTHDSTFELYSTSQMGSTLSLADKPKGMIRSGSFRDPVDDVHGSVLSLASSASSTYSSQIRKLRRELESSQEKVATLTSQLSANANLVAAFEQSLVSMTSRLRHLAETAEEKDTELLDLRETIDFLKKKNSEAQAVIQGALNGTDVAPKELRIKRQNSSDSISSLNSITSHSSISSSKDADAKKKKKKSWLRSSFNKAFSIKKGPKSASSYSDIEEIATPDSSAPSSPKLQHGSTETASPSIKSSTSSSVGIDTAELFQAHSEGEPEKKEVSELRSELWEKEMKLTDIRLEALNSAHQLEQLRETMHNMQLEVDLLKAENDRLKVAPGPSAVPGSIPGHITSTSASSSPRRSLGLSLGHAFSPSPGDADMSPMDAVSAGTQKDELTLRIVVRMPPQHIIKGDLKQQEFFLGWTKVSGKVDWKMLDEAVCQVFKDYITKMDPASTLGLSTESVYGYSISHIKRVLDTEPPELPLCRRGMSSIVVTLKGLKEKCVDSLVFETLIPKPMMQHYISLLLKHRRLILSGPSGTGKTYLTNRLAEYLVERSGRDVTEGIVSTFNMHQQSCKDLQLYLSNLANQIDRETGTADVPLVILLDDLSEAGSISELVNGALTCKYHKCPYIIGTTNQPVKMTPNHGLHLSFRMLTFSNNVEPANGFLVRYLRRKLLESDTDVNANKEELLRVLDWVPKLWYHLHTFLEKHSTSDFLIGPCFFLSCPIGIEDFRTWFIDLWNNSIIPYLQEGAKDGLKVHGQKAAWEDPVEWVRDTLPWPSAQQDQSKLYHLPPPTIGPHSTVSPPEERTVKDTTPSSLDADPLMAMLLKLQEAANYIESPDRETMVDPDLQSTL", "length": 1796, "header": "tr|A0A8V1A0J5-1|A0A8V1AD28_CHICK Computationally mapped isoform of Neuron navigator 1 OS=Gallus gallus OX=9031 GN=NAV1 PE=3 SV=1 CANONICAL=A0A8V1AD28-1" }, "locus": { "chromosome": "26", "start_pos": 702340, "end_pos": 664925, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063941.1", "url": "https://www.ensembl.org/id/ENSGALT00010063941.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039391.1", "url": "https://www.ensembl.org/id/ENSGALP00010039391.1" } ] } }, { "isoform_ac": "A0A8V1A5P2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD28/entry#A0A8V1A5P2-1", "sequence": { "sequence": "MIAARGCWGATSRAFPTWSWARRAPAMSRSLSRSEHSLLPPRPAGPQKPPPAAGKPSRIPRGPYAEVKPLSKAPEAGGGGGGGGGGKCDDELLGGKGPAAAGAEEKAYLKVDPELVVTVLGDLEQLLFSQMLDPESQRKRTVQNVLDLRQNLEETMSSLRGSQVSHSSLEMTCYDSDEANPRSVSSLSNRSSPLSWRYGQSSPRLQAGDAPSVGGGCRSEGTPGWYMHGERAHYSHTMPMRSPSKLSHISRLELVEALDSDDVELKSGYMSDSDLMGKTLTEDDDITTGWDESSSISSGLSDASDNLSSEEFNASSSLNSLPSTPTASRRNSAIALRTDSEKRSLAESGLSWYGEADDKAPKKLDYDSSSLKMEHGSSKWRREPTESCEEGSKGGELKKPVSLGTPGSLKKGKTPPVAVTSPITHTAQSTLKVAGKPETKATDKSKLSVKNTGLQRSSSDAGRDRVGDAKKPPSGLTRPLASSSFGYKKPAPATGTATVMQAGGSATLGKIQKSSGIPVKPVSGRKTSLDVSNTAEPGFLAPGARTNIQYRSLPRPAKSSSMSVTGGRGANRPVSSSIDPSLLSTKQASITVSRLKEPSKISAGRGTPAPVNQTDREKEKAKAKAVALDSECVTLKSIGSPESTPKAQANLPPAAKVAELPPTPLRAAAKTYVKPPSLANLDKVNSNSLDLPSSSELHPPHAAKLQDLHPAGGHLTPCFSPSPAPILNINSASFSQGLELMGGFSVPKEGRMYPKLSGLHRSMESLQMPMSLPSAFSGGSTATPSPAAVPPASTEEEEEAGELGWSGSPRLAHLDSTNRDRNTLPKKGLRYQLHSQEEAKERRHSHTIGGLPEADDQPELPSPPALPMALVGKGPLTSIVSPTATTTPRITRSNSIPTHDSTFELYSTSQMGSTLSLADKPKGMIRSGSFRDPVDDVHGSVLSLASSASSTYSSAEEKMQSEQIRKLRRELESSQEKVATLTSQLSANANLVAAFEQSLVSMTSRLRHLAETAEEKDTELLDLRETIDFLKKKNSEAQAVIQGALNGTDVAPKELRIKRQNSSDSISSLNSITSHSSISSSKDADAKKKKKKSWVYELRSSFNKAFSIKKGPKSASSYSDIEEIATPDSSAPSSPKLQHGSTETASPSIKSSTSSSVGIDTAELFQAHSEGEPEKKEVSELRSELWEKEMKLTDIRLEALNSAHQLEQLRETMHNMQLEVDLLKAENDRLKVAPGPSAVPGSIPGHITSTSASSSPRRSLGLSLGHAFSPSPGDADMSPMDAVSAGTQKDELTLRIVVRMPPQHIIKGDLKQQEFFLGWTKVSGKVDWKMLDEAVCQVFKDYITKMDPASTLGLSTESVYGYSISHIKRVLDTEPPELPLCRRGMSSIVVTLKGLKEKCVDSLVFETLIPKPMMQHYISLLLKHRRLILSGPSGTGKTYLTNRLAEYLVERSGRDVTEGIVSTFNMHQQSCKDLQLYLSNLANQIDRETGTADVPLVILLDDLSEAGSISELVNGALTCKYHKCPYIIGTTNQPVKMTPNHGLHLSFRMLTFSNNVEPANGFLVRYLRRKLLESDTDVNANKEELLRVLDWVPKLWYHLHTFLEKHSTSDFLIGPCFFLSCPIGIEDFRTWFIDLWNNSIIPYLQEGAKDGLKVHGQKAAWEDPVEWVRDTLPWPSAQQDQSKLYHLPPPTIGPHSTVSPPEERTVKDTTPSSLDADPLMAMLLKLQEAANYIESPDRETMVDPDLQSTL", "length": 1750, "header": "tr|A0A8V1A5P2-1|A0A8V1AD28_CHICK Computationally mapped isoform of Neuron navigator 1 OS=Gallus gallus OX=9031 GN=NAV1 PE=3 SV=1 CANONICAL=A0A8V1AD28-1" }, "locus": { "chromosome": "26", "start_pos": 702340, "end_pos": 668504, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063932.1", "url": "https://www.ensembl.org/id/ENSGALT00010063932.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039388.1", "url": "https://www.ensembl.org/id/ENSGALP00010039388.1" } ] } }, { "isoform_ac": "A0A8V1A842-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD28/entry#A0A8V1A842-1", "sequence": { "sequence": "MNGTANLAPTARGHFTSAIPVPRSTTPNKPPAAAPPARHSTSGPPASHRATSPRPAALLGPKSLKPRPRASGHEATESPGVPPHGGQRTPVLPGKGLGGSQVECSLRGAGAHRPLGMAVEDGPNASPMSRSPMFGSGAISFSSASPQSRPVTATVAPFQYRLQEDREQNATSLCDSTPAEVPDPKSRAMTAPGGLNDCSAGMLGSNLKSLPDVELGEEGAAELRGYRRGPDGGGAVMPKRAKAAAAAAGGPRGAELRVFKASSAEGRLPAGSNLRKQKSLTNLAFLTDAEKKRQLYEPRWSDDMAKGTGSTAVAAGGRGGGGGPRGREAPAMSRSLSRSEHSLLPPRPAGPQKPPPAAGKPSRIPRGPYAEVKPLSKAPEAGGGGGGGGGGKCDDELLGGKGPAAAGAEEKAYLKVDPELVVTVLGDLEQLLFSQMLDPESQRKRTVQNVLDLRQNLEETMSSLRGSQVSHSSLEMTCYDSDEANPRSVSSLSNRSSPLSWRYGQSSPRLQAGDAPSVGGGCRSEGTPGWYMHGERAHYSHTMPMRSPSKLSHISRLELVEALDSDDVELKSGYMSDSDLMGKTLTEDDDITTGWDESSSISSGLSDASDNLSSEEFNASSSLNSLPSTPTASRRNSAIALRTDSEKRSLAESGLSWYGEADDKAPKKLDYDSSSLKMEHGSSKWRREPTESCEEGSKGGELKKPVSLGTPGSLKKGKTPPVAVTSPITHTAQSTLKVAGKPETKATDKSKLSVKNTGLQRSSSDAGRDRVGDAKKPPSGLTRPLASSSFGYKKPAPATGTATVMQAGGSATLGKIQKSSGIPVKPVSGRKTSLDVSNTAEPGFLAPGARTNIQYRSLPRPAKSSSMSVTGGRGANRPVSSSIDPSLLSTKQASITVSRLKEPSKISAGRGTPAPVNQTDREKEKAKAKAVALDSECVTLKSIGSPESTPKAQANLPPAAKVAELPPTPLRAAAKTYVKPPSLANLDKVNSNSLDLPSSSELHPPHAAKLQDLHPAGGHLTPCFSPSPAPILNINSASFSQGLELMGGFSVPKEGRMYPKLSGLHRSMESLQMPMSLPSAFSGGSTATPSPAAVPPASTEEEEEAGELGWSGSPRLAHLDSTNRDRNTLPKKGLRYQLHSQEEAKERRHSHTIGGLPEADDQPELPSPPALPMALVGKGPLTSIVHGSVLSLASSASSTYSSQIRKLRRELESSQEKVATLTSQLSANANLVAAFEQSLVSMTSRLRHLAETAEEKDTELLDLRETIDFLKKKNSEAQAVIQGALNGTDVAPKELRIKRQNSSDSISSLNSITSHSSISSSKDADAKKKKKKSWLRSSFNKAFSIKKGPKSASSYSDIEEIATPDSSAPSSPKLQHGSTETASPSIKSSTSSSVGIDTAELFQAHSEGEPEKKEVSELRSELWEKEMKLTDIRLEALNSAHQLEQLRETMHNMQLEVDLLKAENDRLKVAPGPSAVPGSIPGHITSTSASSSPRRSLGLSLGHAFSPSPGDADMSPMDAVSAGTQKDELTLRIVVRMPPQHIIKGDLKQQEFFLGWTKVSGKVDWKMLDEAVCQVFKDYITKMDPASTLGLSTESVYGYSISHIKRVLDTEPPELPLCRRGMSSIVVTLKGLKEKCVDSLVFETLIPKPMMQHYISLLLKHRRLILSGPSGTGKTYLTNRLAEYLVERSGRDVTEGIVSTFNMHQQSCKDLQLYLSNLANQIDRETGTADVPLVILLDDLSEAGSISELVNGALTCKYHKCPYIIGTTNQPVKMTPNHGLHLSFRMLTFSNNVEPANGFLVRYLRRKLLESDTDVNANKEELLRVLDWVPKLWYHLHTFLEKHSTSDFLIGPCFFLSCPIGIEDFRTWFIDLWNNSIIPYLQEGAKDGLKVHGQKAAWEDPVEWVRDTLPWPSAQQDQSKLYHLPPPTIGPHSTVSPPEERTVKDTTPSSLDADPLMAMLLKLQEAANYIESPDRETMVDPDLQSTL", "length": 1987, "header": "tr|A0A8V1A842-1|A0A8V1AD28_CHICK Computationally mapped isoform of Neuron navigator 1 OS=Gallus gallus OX=9031 GN=NAV1 PE=3 SV=1 CANONICAL=A0A8V1AD28-1" }, "locus": { "chromosome": "26", "start_pos": 702340, "end_pos": 664925, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063952.1", "url": "https://www.ensembl.org/id/ENSGALT00010063952.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039395.1", "url": "https://www.ensembl.org/id/ENSGALP00010039395.1" } ] } }, { "isoform_ac": "A0A8V1AAW0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD28/entry#A0A8V1AAW0-1", "sequence": { "sequence": "MNGTANLAPTARGHFTSAIPVPRSTTPNKPPAAAPPARHSTSGPPASHRATSPRPAALLGPKSLKPRPRASGHEATESPGVPPHGGQRTPVLPGKGLGGSQVECSLRGAGAHRPLGMAVEDGPNASPMSRSPMFGSGAISFSSASPQSRPVTATVAPFQYRLQEDREQNATSLCDSTPAEVPDPKSRAMTAPGGLNDCSAGMLGSNLKSLPDVELGEEGAAELRGYRRGPDGGGAVMPKRAKAAAAAAGGPRGAELRVFKASSAEGRLPAGSNLRKQKSLTNLAFLTDAEKKRQLYEPRWSDDMAKGTGSTAVAAGGRGGGGGPRGREAPAMSRSLSRSEHSLLPPRPAGPQKPPPAAGKPSRIPRGPYAEVKPLSKAPEAGGGGGGGGGGKCDDELLGGKGPAAAGAEEKAYLKVDPELVVTVLGDLEQLLFSQMLDPESQRKRTVQNVLDLRQNLEETMSSLRGSQVSHSSLEMTCYDSDEANPRSVSSLSNRSSPLSWRYGQSSPRLQAGDAPSVGGGCRSEGTPGWYMHGERAHYSHTMPMRSPSKLSHISRLELVEALDSDDVELKSGYMSDSDLMGKTLTEDDDITTGWDESSSISSGLSDASDNLSSEEFNASSSLNSLPSTPTASRRNSAIALRTDSEKRSLAESGLSWYGEADDKAPKKLDYDSSSLKMEHGSSKWRREPTESCEEGSKGGELKKPVSLGTPGSLKKGKTPPVAVTSPITHTAQSTLKVAGKPETKATDKSKLSVKNTGLQRSSSDAGRDRVGDAKKPPSGLTRPLASSSFGYKKPAPATGTATVMQAGGSATLGKIQKSSGIPVKPVSGRKTSLDVSNTAEPGFLAPGARTNIQYRSLPRPAKSSSMSVTGGRGANRPVSSSIDPSLLSTKQASITVSRLKEPSKISAGRGTPAPVNQTDREKEKAKAKAVALDSECVTLKSIGSPESTPKAQANLPPAAKVAELPPTPLRAAAKTYVKPPSLANLDKVNSNSLDLPSSSELHPPHAAKLQDLHPAGGHLTPCFSPSPAPILNINSASFSQGLELMGGFSVPKEGRMYPKLSGLHRSMESLQMPMSLPSAFSGGSTATPSPAAVPPASTEEEEEAGELGWSGSPRLAHLDSTNRDRNTLPKKGLRYQLHSQEEAKERRHSHTIGGLPEADDQPELPSPPALPMALVGKGPLTSIVSPTATTTPRITRSNSIPTHDSTFELYSTSQMGSTLSLADKPKGMIRSGSFRDPVDDVHGSVLSLASSASSTYSSQIRKLRRELESSQEKVATLTSQLSANANLVAAFEQSLVSMTSRLRHLAETAEEKDTELLDLRETIDFLKKKNSEAQAVIQGALNGTDVAPKELRIKRQNSSDSISSLNSITSHSSISSSKDADAKKKKKKSWLRSSFNKAFSIKKGPKSASSYSDIEEIATPDSSAPSSPKLQHGSTETASPSIKSSTSSSVGIDTAELFQAHSEGEPEKKEVSELRSELWEKEMKLTDIRLEALNSAHQLEQLRETMHNMQLEVDLLKAENDRLKVAPGPSAVPGSIPGHITSTSASSSPRRSLGLSLGHAFSPSPGDADMSPMDAVSAGTQKDELTLRIVVRMPPQHIIKGDLKQQEFFLGWTKVSGKVDWKMLDEAVCQVFKDYITKMDPASTLGLSTESVYGYSISHIKRVLDTEPPELPLCRRGMSSIVVTLKGLKEKCVDSLVFETLIPKPMMQHYISLLLKHRRLILSGPSGTGKTYLTNRLAEYLVERSGRDVTEGIVSTFNMHQQSCKDLQLYLSNLANQIDRETGTADVPLVILLDDLSEAGSISELVNGALTCKYHKCPYIIGTTNQPVKMTPNHGLHLSFRMLTFSNNVEPANGFLVRYLRRKLLESDTDVNANKEELLRVLDWVPKLWYHLHTFLEKHSTSDFLIGPCFFLSCPIGIEDFRTWFIDLWNNSIIPYLQEGAKDGLKVHGQKAAWEDPVEWVRDTLPWPSAQQDQSKLYHLPPPTIGPHSTVSPPEERTVKDTTPSSLDADPLMAMLLKLQEAANYIESPDRETMVDPDLQSTL", "length": 2044, "header": "tr|A0A8V1AAW0-1|A0A8V1AAW0_CHICK Computationally mapped isoform of Neuron navigator 1 OS=Gallus gallus OX=9031 GN=NAV1 PE=3 SV=1 CANONICAL=A0A8V1AD28-1" }, "locus": { "chromosome": "26", "start_pos": 702340, "end_pos": 664925, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063969.1", "url": "https://www.ensembl.org/id/ENSGALT00010063969.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039399.1", "url": "https://www.ensembl.org/id/ENSGALP00010039399.1" } ] } }, { "isoform_ac": "A0A8V1AD18-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD28/entry#A0A8V1AD18-1", "sequence": { "sequence": "MLRAGRPRRAPRLVASWDESSSISSGLSDASDNLSSEEFNASSSLNSLPSTPTASRRNSAIALRTDSEKRSLAESGLSWYGEADDKAPKKLDYDSSSLKMEHGSSKWRREPTESCEEGSKGGELKKPVSLGTPGSLKKGKTPPVAVTSPITHTAQSTLKVAGKPETKATDKSKLSVKNTGLQRSSSDAGRDRVGDAKKPPSGLTRPLASSSFGYKKPAPATGTATVMQAGGSATLGKIQKSSGIPVKPVSGRKTSLDVSNTAEPGFLAPGARTNIQYRSLPRPAKSSSMSVTGGRGANRPVSSSIDPSLLSTKQASITVSRLKEPSKISAGRGTPAPVNQTDREKEKAKAKAVALDSECVTLKSIGSPESTPKAQANLPPAAKVAELPPTPLRAAAKTYVKPPSLANLDKVNSNSLDLPSSSELHPPHAAKLQDLHPAGGHLTPCFSPSPAPILNINSASFSQGLELMGGFSVPKEGRMYPKLSGLHRSMESLQMPMSLPSAFSGGSTATPSPAAVPPASTEEEEEAGELGWSGSPRLAHLDSTNRDRNTLPKKGLRYQLHSQEEAKERRHSHTIGGLPEADDQPELPSPPALPMALVGKGPLTSIVSPTATTTPRITRSNSIPTHDSTFELYSTSQMGSTLSLADKPKGMIRSGSFRDPVDDVHGSVLSLASSASSTYSSAEEKMQSEQIRKLRRELESSQEKVATLTSQLSANANLVAAFEQSLVSMTSRLRHLAETAEEKDTELLDLRETIDFLKKKNSEAQAVIQGALNGTDVAPKELRIKRQNSSDSISSLNSITSHSSISSSKDADAKKKKKKSWVYELRSSFNKAFSIKKGPKSASSYSDIEEIATPDSSAPSSPKLQHGSTETASPSIKSSTSSSVGIDTAELFQAHSEGEPEKKEVSELRSELWEKEMKLTDIRLEALNSAHQLEQLRETMHNMQLEVDLLKAENDRLKVAPGPSAVPGSIPGHITSTSASSSPRRSLGLSLGHAFSPSPGDADMSPMDAVSAGTQKDELTLRIVVRMPPQHIIKGDLKQQEFFLGWTKVSGKVDWKMLDEAVCQVFKDYITKMDPASTLGLSTESVYGYSISHIKRVLDTEPPELPLCRRGMSSIVVTLKGLKEKCVDSLVFETLIPKPMMQHYISLLLKHRRLILSGPSGTGKTYLTNRLAEYLVERSGRDVTEGIVSTFNMHQQSCKDLQLYLSNLANQIDRETGTADVPLVILLDDLSEAGSISELVNGALTCKYHKCPYIIGTTNQPVKMTPNHGLHLSFRMLTFSNNVEPANGFLVRYLRRKLLESDTDVNANKEELLRVLDWVPKLWYHLHTFLEKHSTSDFLIGPCFFLSCPIGIEDFRTWFIDLWNNSIIPYLQEGAKDGLKVHGQKAAWEDPVEWVRDTLPWPSAQQDQSKLYHLPPPTIGPHSTVSPPEERTVKDTTPSSLDADPLMAMLLKLQEAANYIESPDRETMVDPDLQSTL", "length": 1477, "header": "tr|A0A8V1AD18-1|A0A8V1AD18_CHICK Computationally mapped isoform of Neuron navigator 1 OS=Gallus gallus OX=9031 GN=NAV1 PE=3 SV=1 CANONICAL=A0A8V1AD28-1" }, "locus": { "chromosome": "26", "start_pos": 702340, "end_pos": 689163, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063923.1", "url": "https://www.ensembl.org/id/ENSGALT00010063923.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039387.1", "url": "https://www.ensembl.org/id/ENSGALP00010039387.1" } ] } }, { "isoform_ac": "A0A8V1AD28-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD28/entry#A0A8V1AD28-1", "sequence": { "sequence": "MNGTANLAPTARGHFTSAIPVPRSTTPNKPPAAAPPARHSTSGPPASHRATSPRPAALLGPKSLKPRPRASGHEATESPGVPPHGGQRTPVLPGKGLGGSQVECSLRGAGAHRPLGMAVEDGPNASPMSRSPMFGSGAISFSSASPQSRPVTATVAPFQYRLQEDREQNATSLCDSTPAEVPDPKSRAMTPGGLNDCSAGMLGSNLKSLPDVELGEEGAAELRGYRRGPDGGGAVMPKRAKAAAAAAGGPRGAELRVFKASSAEGRLPAGSNLRKQKSLTNLAFLTDAEKKRQLYEPRWSDDMAKGTGSTAVAAGGRGGGGGPRGREAPAMSRSLSRSEHSLLPPRPAGPQKPPPAAGKPSRIPRGPYAEVKPLSKAPEAGGGGGGGGGGKCDDELLGGKGPAAAGAEEKAYLKVDPELVVTVLGDLEQLLFSQMLDPESQRKRTVQNVLDLRQNLEETMSSLRGSQVSHSSLEMTCYDSDEANPRSVSSLSNRSSPLSWRYGQSSPRLQAGDAPSVGGGCRSEGTPGWYMHGERAHYSHTMPMRSPSKLSHISRLELVEALDSDDVELKSGYMSDSDLMGKTLTEDDDITTGWDESSSISSGLSDASDNLSSEEFNASSSLNSLPSTPTASRRNSAIALRTDSEKRSLAESGLSWYGEADDKAPKKLDYDSSSLKMEHGSSKWRREPTESCEEGSKGGELKKPVSLGTPGSLKKGKTPPVAVTSPITHTAQSTLKVAGKPETKATDKSKLSVKNTGLQRSSSDAGRDRVGDAKKPPSGLTRPLASSSFGYKKPAPATGTATVMQAGGSATLGKIQKSSGIPVKPVSGRKTSLDVSNTAEPGFLAPGARTNIQYRSLPRPAKSSSMSVTGGRGANRPVSSSIDPSLLSTKQASITVSRLKEPSKISAGRGTPAPVNQTDREKEKAKAKAVALDSECVTLKSIGSPESTPKAQANLPPAAKVAELPPTPLRAAAKTYVKPPSLANLDKVNSNSLDLPSSSELHPPHAAKLQDLHPAGGHLTPCFSPSPAPILNINSASFSQGLELMGGFSVPKEGRMYPKLSGLHRSMESLQMPMSLPSAFSGGSTATPSPAAVPPASTEEEEEAGELGWSGSPRLAHLDSTNRDRNTLPKKGLRYQLHSQEEAKERRHSHTIGGLPEADDQPELPSPPALPMALVGKGPLTSIVSPTATTTPRITRSNSIPTHDSTFELYSTSQMGSTLSLADKPKGMIRSGSFRDPVDDVHGSVLSLASSASSTYSSAEEKMQSEQIRKLRRELESSQEKVATLTSQLSANANLVAAFEQSLVSMTSRLRHLAETAEEKDTELLDLRETIDFLKKKNSEAQAVIQGALNGTDVAPKELRIKRQNSSDSISSLNSITSHSSISSSKDADAKKKKKKSWLRSSFNKAFSIKKGPKSASSYSDIEEIATPDSSAPSSPKLQHGSTETASPSIKSSTSSSVGIDTAELFQAHSEGEPEKKEVSELRSELWEKEMKLTDIRLEALNSAHQLEQLRETMHNMQLEVDLLKAENDRLKVAPGPSAVPGSIPGHITSTSASSSPRRSLGLSLGHAFSPSPGDADMSPMDAVSAGTQKDELTLRIVVRMPPQHIIKGDLKQQEFFLGWTKVSGKVDWKMLDEAVCQVFKDYITKMDPASTLGLSTESVYGYSISHIKRVLDTEPPELPLCRRGMSSIVVTLKGLKEKCVDSLVFETLIPKPMMQHYISLLLKHRRLILSGPSGTGKTYLTNRLAEYLVERSGRDVTEGIVSTFNMHQQSCKDLQLYLSNLANQIDRETGTADVPLVILLDDLSEAGSISELVNGALTCKYHKCPYIIGTTNQPVKMTPNHGLHLSFRMLTFSNNVEPANGFLVRYLRRKLLESDTDVNANKEELLRVLDWVPKLWYHLHTFLEKHSTSDFLIGPCFFLSCPIGIEDFRTWFIDLWNNSIIPYLQEGAKDGLKVHGQKAAWEDPVEWVRDTLPWPSAQQDQSKLYHLPPPTIGPHSTVSPPEERTVKDTTPSSLDADPLMAMLLKLQEAANYIESPDRETMVDPDLQSTL", "length": 2051, "header": "tr|A0A8V1AD28-1|A0A8V1AD28_CHICK Isoform 1 of Neuron navigator 1 OS=Gallus gallus OX=9031 GN=NAV1 PE=3 SV=1 CANONICAL=A0A8V1AD28-1" }, "locus": { "chromosome": "26", "start_pos": 702340, "end_pos": 664925, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063960.1", "url": "https://www.ensembl.org/id/ENSGALT00010063960.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039397.1", "url": "https://www.ensembl.org/id/ENSGALP00010039397.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1087, "start_aa": "Thr", "end_pos": 1087, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1087", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 526, "start_aa": "Thr", "end_pos": 526, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr526", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AD28", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD28" } ], "pmid": "" }, { "name": "microtubule cytoskeleton", "id": "GO:0015630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015630", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AD28", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD28" } ], "pmid": "" }, { "name": "axon initial segment", "id": "GO:0043194", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043194", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AD28", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD28" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "neurogenesis", "id": "GO:0022008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022008", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AD28", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD28" } ], "pmid": "" }, { "name": "nervous system development", "id": "GO:0007399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007399", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AD28", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD28" } ], "pmid": "" }, { "name": "neuron migration", "id": "GO:0001764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001764", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AD28", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD28" } ], "pmid": "" }, { "name": "microtubule bundle formation", "id": "GO:0001578", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001578", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AD28", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD28" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 124, "end_pos": 126, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1350, "end_pos": 1352, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1365, "end_pos": 1367, "annotation": "n_glycosylation_sequon" }, { "start_pos": 169, "end_pos": 171, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1938, "end_pos": 1940, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2, "end_pos": 4, "annotation": "n_glycosylation_sequon" }, { "start_pos": 493, "end_pos": 495, "annotation": "n_glycosylation_sequon" }, { "start_pos": 610, "end_pos": 612, "annotation": "n_glycosylation_sequon" }, { "start_pos": 617, "end_pos": 619, "annotation": "n_glycosylation_sequon" }, { "start_pos": 916, "end_pos": 918, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AD28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD28" }, { "id": "SM00382", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00382" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "AAA+ ATPase", "eco_id": "ECO_0000259", "start_pos": 1724, "end_pos": 1863, "start_aa": "Lys", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 526, 1087 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 124, "end_pos": 126 }, { "start_pos": 1350, "end_pos": 1352 }, { "start_pos": 1365, "end_pos": 1367 }, { "start_pos": 169, "end_pos": 171 }, { "start_pos": 1938, "end_pos": 1940 }, { "start_pos": 2, "end_pos": 4 }, { "start_pos": 493, "end_pos": 495 }, { "start_pos": 610, "end_pos": 612 }, { "start_pos": 617, "end_pos": 619 }, { "start_pos": 916, "end_pos": 918 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": 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"categories": [ "Protein Classification" ] }, { "id": "IPR050113", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050113", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A0M4", "url": "https://www.orthodb.org/?gene=A0A8V1A0M4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A5S3", "url": "https://www.orthodb.org/?gene=A0A8V1A5S3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AAY3", "url": "https://www.orthodb.org/?gene=A0A8V1AAY3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24067", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24067", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24068", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24068", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00179", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00179", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1A0M4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0M4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A0M4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0M4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A5S3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5S3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A5S3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5S3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AAY3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAY3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AAY3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAY3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "PTATARRGGASRRVRPPVRGRDLVVDTAHFGGDRGLPRPRADPGGVSSPSPRPLISPRPLIRPRPQELEEVRRWGGVRDLQLVDRDVLRWRGLLLPNNPPYNAGAFRFELVFSPHYPLVPPRVTLLTGIHHPGVGPDGTVCQPIASPESWEPLTRITHVLQDLLLLLDNPSTERVLRPELARELSERPEAFLHQAEEHTRRYAEPRPDTPGP", "length": 212, "header": "tr|A0A8V1AAY3-1|A0A8V1AAY3_CHICK Isoform 1 of Ubiquitin conjugating enzyme E2 L6 OS=Gallus gallus OX=9031 GN=UBE2L6 PE=1 SV=1 CANONICAL=A0A8V1AAY3-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A0M4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAY3/entry#A0A8V1A0M4-1", "sequence": { "sequence": "MSRRLAMNNPPYNAGAFRFELVFSPHYPLVPPRVTLLTGIHHPGVGPDGTVCQPIASPESWEPLTRITHVLQDLLLLLDNPSTERVLRPELARELSERPEAFLHQAEEHTRRYAEPRPDTPGP", "length": 123, "header": "tr|A0A8V1A0M4-1|A0A8V1AAY3_CHICK Computationally mapped isoform of Ubiquitin conjugating enzyme E2 L6 OS=Gallus gallus OX=9031 GN=UBE2L6 PE=1 SV=1 CANONICAL=A0A8V1AAY3-1" }, "locus": { "chromosome": "5", "start_pos": 16562291, "end_pos": 16561040, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010064047.1", "url": "https://www.ensembl.org/id/ENSGALT00010064047.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039421.1", "url": "https://www.ensembl.org/id/ENSGALP00010039421.1" } ] } }, { "isoform_ac": "A0A8V1A5S3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAY3/entry#A0A8V1A5S3-1", "sequence": { "sequence": "MSRRLAMELEEVRRWGGVRDLQLVDRDVLRWRGLLLPNNPPYNAGAFRFELVFSPHYPLVPPRVTLLTGIHHPGVGPDGTVCQPIASPESWEPLTRITHGRCWGPGVGDMASALADAPPVSHSAAGPAAAAGQPQHRAGAAPRAGPRAEREARGLPAPGRGAHPSLRRAASRHPRALSPHLGAPRPVHKAPT", "length": 192, "header": "tr|A0A8V1A5S3-1|A0A8V1AAY3_CHICK Computationally mapped isoform of Ubiquitin conjugating enzyme E2 L6 OS=Gallus gallus OX=9031 GN=UBE2L6 PE=1 SV=1 CANONICAL=A0A8V1AAY3-1" }, "locus": { "chromosome": "5", "start_pos": 16562338, "end_pos": 16561040, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010064055.1", "url": "https://www.ensembl.org/id/ENSGALT00010064055.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039423.1", "url": "https://www.ensembl.org/id/ENSGALP00010039423.1" } ] } }, { "isoform_ac": "A0A8V1AAY3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAY3/entry#A0A8V1AAY3-1", "sequence": { "sequence": "PTATARRGGASRRVRPPVRGRDLVVDTAHFGGDRGLPRPRADPGGVSSPSPRPLISPRPLIRPRPQELEEVRRWGGVRDLQLVDRDVLRWRGLLLPNNPPYNAGAFRFELVFSPHYPLVPPRVTLLTGIHHPGVGPDGTVCQPIASPESWEPLTRITHVLQDLLLLLDNPSTERVLRPELARELSERPEAFLHQAEEHTRRYAEPRPDTPGP", "length": 212, "header": "tr|A0A8V1AAY3-1|A0A8V1AAY3_CHICK Isoform 1 of Ubiquitin conjugating enzyme E2 L6 OS=Gallus gallus OX=9031 GN=UBE2L6 PE=1 SV=1 CANONICAL=A0A8V1AAY3-1" }, "locus": { "chromosome": "5", "start_pos": 16562291, "end_pos": 16561281, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010064044.1", "url": "https://www.ensembl.org/id/ENSGALT00010064044.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039419.1", "url": "https://www.ensembl.org/id/ENSGALP00010039419.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AAY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAY3" }, { "id": "PS50127", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50127" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "UBC core", "eco_id": "ECO_0000259", "start_pos": 59, "end_pos": 204, "start_aa": "Pro", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1ADK9-1", "uniprot_ac": "A0A8V1ADK9", "uniprot_id": "A0A8V1ADK9_CHICK", "mass": { "chemical_mass": 57476.0, "monoisotopic_mass": 57476.0 }, "refseq": {}, "gene_names": [ { "name": "LAD1", "type": "recommended", "evidence": [ { "id": "A0A8V1ADK9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADK9" } ] } ], "protein_names": [ { "name": "Ladinin 1", "type": "synonym", "evidence": [ { "id": "A0A8V1ADK9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADK9/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADK9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADK9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LAD1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADK9", "locus": { "chromosome": "26", "start_pos": 841974, "end_pos": 833932, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010026638", "url": "https://www.ensembl.org/id/ENSGALG00010026638" } ] } } ], "crossref": [ { "id": "A0A8V1ADK9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1ADK9", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR017404", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017404", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A149", "url": "https://www.orthodb.org/?gene=A0A8V1A149", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A8N7", "url": "https://www.orthodb.org/?gene=A0A8V1A8N7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ABH9", "url": "https://www.orthodb.org/?gene=A0A8V1ABH9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ADK9", "url": "https://www.orthodb.org/?gene=A0A8V1ADK9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12392", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12392", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12392:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12392:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A149", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A149", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A149-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A149-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A8N7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8N7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A8N7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8N7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ABH9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABH9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ABH9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABH9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ADK9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADK9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ADK9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADK9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTVLDPGEPAAASSHAPTAIHLLQPLAGGGDGRRVLVEQVLGWELSPKPWETWMDPAQSAGLAASPGTAGSELSSALRGTPGQGGFCTALLVDKLQPCLCPVPADPPWPGCLRGFGAAGDPREAAMSFSRRNWSDLSSLARQRTLEDEEEQQRERRRRHRSLLSSSSMDEDHPSPGKDPSPAPSRPQAPVKPTAPEEDEESKLTEVLRTKEGRRMRSPMAVSEKPKQEKEQQEAGMKPRTGQGSIAAAERGQNTAPAGEQQPEQSHERKVTARGRLQDREGSSVGTLRGEQRREEQQQRAAPELGGCRLREVKILTRTRSSSTEEKAASEGTSPPAPQQPPRSPSKEGMQPPPSQEEPTEGRDAPPAPATYSSSIRRSSPRTVSFRVISNKQKEESESPLTRSASMRIPGSSSSIEEKLEKYTSAVQRSGSVRSSLTVQKSLVLTSDGVASKRNFFEASTPSKAEPFAARKDNLKIPGSVTSRINLWISRTQEPAKDEKSKDIRRISSLPKRDVWVKQPRESPADTEL", "length": 528, "header": "tr|A0A8V1ADK9-1|A0A8V1ADK9_CHICK Isoform 1 of Ladinin 1 OS=Gallus gallus OX=9031 GN=LAD1 PE=1 SV=1 CANONICAL=A0A8V1ADK9-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A149-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADK9/entry#A0A8V1A149-1", "sequence": { "sequence": "MDPAQSAGLAASPGTAGSELSSALRGTPGQGGFCTALLVDKLQPCLCPVPADPPWPGCLRGFGAAGDPREAAMSFSRRNWSDLSSLARQRTLEDEEEQQRERRRRHRSLLSSSSMDEDHPSPGKDPSPAPSRPQAPVKPTAPEEDEESKLTEVLRTKEGRRMRSPMAVSEKPKQEKEQQEAGMKPRTGQGSIAAAERGQNTAPAGEQQPEQSHERKVTARGRLQDREGSSVGTLRGEQRREEQQQRAAPELGGCRLREVKILTRTRSSSTEEKAASEGTSPPAPQQPPRSPSKEGMQPPPSQEEPTEGRDAPPAPATYSSSIRRSSPRTVSFRVISNKQKEESESPLTRSASMRIPGSSSSIEEKLEKYTSAVQRSGSVRSSLTVQKSLVLTSDGVASKRNFFEASTPSKAEPFAARKDNLKIPGSVTSRINLWISRTQEPAKDEKSKVTACAIASG", "length": 457, "header": "tr|A0A8V1A149-1|A0A8V1ADK9_CHICK Computationally mapped isoform of Ladinin 1 OS=Gallus gallus OX=9031 GN=LAD1 PE=1 SV=1 CANONICAL=A0A8V1ADK9-1" }, "locus": { "chromosome": "26", "start_pos": 840331, "end_pos": 834177, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010064689.1", "url": "https://www.ensembl.org/id/ENSGALT00010064689.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039592.1", "url": "https://www.ensembl.org/id/ENSGALP00010039592.1" } ] } }, { "isoform_ac": "A0A8V1A8N7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADK9/entry#A0A8V1A8N7-1", "sequence": { "sequence": "MLGPGAAAWSAMWGRILWGLLARQRTLEDEEEQQRERRRRHRSLLSSSSMDEDHPSPGKDPSPAPSRPQAPVKPTAPEEDEESKLTEVLRTKEGRRMRSPMAVSEKPKQEKEQQEAGMKPRTGQGSIAAAERGQNTAPAGEQQPEQSHERKVTARGRLQDREGSSVGTLRGEQRREEQQQRAAPELGGCRLREVKILTRTRSSSTEEKAASEGTSPPAPQQPPRSPSKEGMQPPPSQEEPTEGRDAPPAPATYSSSIRRSSPRTVSFRVISNKQKEESESPLTRSASMRIPGSSSSIEEKLEKYTSAVQRSGSVRSSLTVQKSLVLTSDGVASKRNFFEASTPSKAEPFAARKDNLKIPGSVTSRINLWISRTQEPAKDEKSKDIRRISSLPKRDVWVKQPRESPADTEL", "length": 410, "header": "tr|A0A8V1A8N7-1|A0A8V1ADK9_CHICK Computationally mapped isoform of Ladinin 1 OS=Gallus gallus OX=9031 GN=LAD1 PE=1 SV=1 CANONICAL=A0A8V1ADK9-1" }, "locus": { "chromosome": "26", "start_pos": 841202, "end_pos": 836147, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010064685.1", "url": "https://www.ensembl.org/id/ENSGALT00010064685.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039591.1", "url": "https://www.ensembl.org/id/ENSGALP00010039591.1" } ] } }, { "isoform_ac": "A0A8V1ABH9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADK9/entry#A0A8V1ABH9-1", "sequence": { "sequence": "MLWLRPAAAHGDPPGARGWDPCCGSGALLSSSLARQRTLEDEEEQQRERRRRHRSLLSSSSMDEDHPSPGKDPSPAPSRPQAPVKPTAPEEDEESKLTEVLRTKEGRRMRSPMAVSEKPKQEKEQQEAGMKPRTGQGSIAAAERGQNTAPAGEQQPEQSHERKVTARGRLQDREGSSVGTLRGEQRREEQQQRAAPELGGCRLREVKILTRTRSSSTEEKAASEGTSPPAPQQPPRSPSKEGMQPPPSQEEPTEGRDAPPAPATYSSSIRRSSPRTVSFRVISNKQKEESESPLTRSASMRIPGSSSSIEEKLEKYTSAVQRSGSVRSSLTVQKSLVLTSDGVASKRNFFEASTPSKAEPFAARKDNLKIPGSVTSRINLWISRTQEPAKDEKSKDIRRISSLPKRDVWVKQPRESPADTEL", "length": 422, "header": "tr|A0A8V1ABH9-1|A0A8V1ABH9_CHICK Computationally mapped isoform of Ladinin 1 OS=Gallus gallus OX=9031 GN=LAD1 PE=1 SV=1 CANONICAL=A0A8V1ADK9-1" }, "locus": { "chromosome": "26", "start_pos": 841202, "end_pos": 836561, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010064682.1", "url": "https://www.ensembl.org/id/ENSGALT00010064682.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039590.1", "url": "https://www.ensembl.org/id/ENSGALP00010039590.1" } ] } }, { "isoform_ac": "A0A8V1ADK9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADK9/entry#A0A8V1ADK9-1", "sequence": { "sequence": "MTVLDPGEPAAASSHAPTAIHLLQPLAGGGDGRRVLVEQVLGWELSPKPWETWMDPAQSAGLAASPGTAGSELSSALRGTPGQGGFCTALLVDKLQPCLCPVPADPPWPGCLRGFGAAGDPREAAMSFSRRNWSDLSSLARQRTLEDEEEQQRERRRRHRSLLSSSSMDEDHPSPGKDPSPAPSRPQAPVKPTAPEEDEESKLTEVLRTKEGRRMRSPMAVSEKPKQEKEQQEAGMKPRTGQGSIAAAERGQNTAPAGEQQPEQSHERKVTARGRLQDREGSSVGTLRGEQRREEQQQRAAPELGGCRLREVKILTRTRSSSTEEKAASEGTSPPAPQQPPRSPSKEGMQPPPSQEEPTEGRDAPPAPATYSSSIRRSSPRTVSFRVISNKQKEESESPLTRSASMRIPGSSSSIEEKLEKYTSAVQRSGSVRSSLTVQKSLVLTSDGVASKRNFFEASTPSKAEPFAARKDNLKIPGSVTSRINLWISRTQEPAKDEKSKDIRRISSLPKRDVWVKQPRESPADTEL", "length": 528, "header": "tr|A0A8V1ADK9-1|A0A8V1ADK9_CHICK Isoform 1 of Ladinin 1 OS=Gallus gallus OX=9031 GN=LAD1 PE=1 SV=1 CANONICAL=A0A8V1ADK9-1" }, "locus": { "chromosome": "26", "start_pos": 841202, "end_pos": 834018, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010064692.1", "url": "https://www.ensembl.org/id/ENSGALT00010064692.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039593.1", "url": "https://www.ensembl.org/id/ENSGALP00010039593.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 193, "start_aa": "Thr", "end_pos": 193, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr193", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "structural molecule activity", "id": "GO:0005198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005198", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADK9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADK9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 132, "end_pos": 134, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 193 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 132, "end_pos": 134 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AC40-1", "uniprot_ac": "A0A8V1AC40", "uniprot_id": "A0A8V1AC40_CHICK", "mass": { "chemical_mass": 54454.0, "monoisotopic_mass": 54454.0 }, "refseq": { "ac": "XP_015154568", "name": "cyclin-dependent kinase 18 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015154568" }, "gene_names": [ { "name": "CDK18", "type": "recommended", "evidence": [ { "id": "A0A8V1AC40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC40" } ] }, { "name": "CDK18", "type": "synonym", "evidence": [ { "id": "XP_015154568", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015154568" } ] } ], "protein_names": [ { "name": "cyclin-dependent kinase", "type": "recommended", "evidence": [ { "id": "A0A8V1AC40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC40/entry#names_and_taxonomy" } ] }, { "name": "2.7.11.22", "type": "synonym", "evidence": [ { "id": "A0A8V1AC40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC40/entry#names_and_taxonomy" } ] }, { "name": "cyclin-dependent kinase 18 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_015154568", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015154568" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052557.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015154568", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015154568" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AC40", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC40" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CDK18", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC40", "locus": { "chromosome": "26", "start_pos": 2210335, "end_pos": 2185342, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010026942", "url": "https://www.ensembl.org/id/ENSGALG00010026942" } ] } } ], "crossref": [ { "id": "A0A8V1AC40", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AC40", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000000692", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000000692", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd07871", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07871", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "771736", "url": "https://www.ncbi.nlm.nih.gov/gene/771736", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008271", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008271", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017441", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017441", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050108", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050108", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:771736", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:771736", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTSVHYR", "url": "https://omabrowser.org/oma/group/PTSVHYR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A1M8", "url": "https://www.orthodb.org/?gene=A0A8V1A1M8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A1N2", "url": "https://www.orthodb.org/?gene=A0A8V1A1N2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A6P5", "url": "https://www.orthodb.org/?gene=A0A8V1A6P5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AC36", "url": "https://www.orthodb.org/?gene=A0A8V1AC36", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AC40", "url": "https://www.orthodb.org/?gene=A0A8V1AC40", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1C3N0", "url": "https://www.orthodb.org/?gene=E1C3N0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24056", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24056", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24056:SF52", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24056:SF52", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00069", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00069", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015154568", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015154568", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "17989", "url": "https://www.rhea-db.org/rhea/17989", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "46608", "url": "https://www.rhea-db.org/rhea/46608", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1A1M8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1M8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A1M8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1M8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A1N2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1N2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A1N2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1N2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A6P5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6P5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A6P5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6P5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AC36", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC36", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AC36-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC36-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AC40", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC40", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AC40-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC40-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C3N0", "url": "https://www.uniprot.org/uniprotkb/E1C3N0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C3N0-1", "url": "https://www.uniprot.org/uniprotkb/E1C3N0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNKMKNFKRRFSLSVPRTETIEESLTEFTEQFNQLNNQRNEDLAQGHLQLGQLDRDIRADPTAISPPDMEGQSPMAVRYRSSTQRRFSTEDVSKRLSLPMDIRLPPEFLQKLQMESPEFPKTLSRMSRRASLSDIGFGKMETYVKLDKLGEGTYATVFKGRSKLTENLVALKEIRLEHEEGAPCTAIREVSLLKNLKHANIVTLHDIIHTERSLTLVFEYLENDLKQYLDNCGNLMSVHNVKIFMFQLLRGLSYCHERKILHRDLKPQNLLINERGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTEYSTPIDMWGVGCIHYEMVTGRPMFPGSTVKEELHLIFRLLGTPTEDTWPGITSNEEFRAYNFTQYRAQPLINHAPRLDSDGIDLLMNLLLYEAKSRISAEVALRHPYFKSLGERVHVLPDNVSIFSLKEIQLQKDPGYRGSAFQQSARGKNRRQSIF", "length": 473, "header": "tr|A0A8V1AC40-1|A0A8V1AC40_CHICK Isoform 1 of cyclin-dependent kinase OS=Gallus gallus OX=9031 GN=CDK18 PE=1 SV=1 CANONICAL=A0A8V1AC40-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A1M8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC40/entry#A0A8V1A1M8-1", "sequence": { "sequence": "MQPHYLQAVRAHCDAHEMLGGMEWASASAHLGDAAADGGGTADLAQGHLQLGQLDRDIRADPTAISPPDMEGQSPMAVRYRSSTQRRFSTEDVSKRLSLPMDIRLPPEFLQKLQMESPEFPKTLSRMSRRASLSDIGFGKMETYVKLDKLGEGTYATVFKGRSKLTENLVALKEIRLEHEEGAPCTAIREVSLLKNLKHANIVTLHDIIHTERSLTLVFEYLENDLKQYLDNCGNLMSVHNVKIFMFQLLRGLSYCHERKILHRDLKPQNLLINERGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTEYSTPIDMWGVGCIHYEMVTGRPMFPGSTVKEELHLIFRLLGTPTEDTWPGITSNEEFRAYNFTQYRAQPLINHAPRLDSDGIDLLMNLLLYEAKSRISAEVALRHPYFKSLGERVHVLPDNVSIFSLKEIQLQKDPGYRGSAFQQSARGKNRRQSIF", "length": 474, "header": "tr|A0A8V1A1M8-1|A0A8V1AC40_CHICK Computationally mapped isoform of cyclin-dependent kinase OS=Gallus gallus OX=9031 GN=CDK18 PE=1 SV=1 CANONICAL=A0A8V1AC40-1" }, "locus": { "chromosome": "26", "start_pos": 2207343, "end_pos": 2201242, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065336.1", "url": "https://www.ensembl.org/id/ENSGALT00010065336.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039769.1", "url": "https://www.ensembl.org/id/ENSGALP00010039769.1" } ] } }, { "isoform_ac": "A0A8V1A1N2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC40/entry#A0A8V1A1N2-1", "sequence": { "sequence": "MGREGRRRTKPFPSPTPSSSTSSSRGKMNKMKNFKRRFSLSVPRTETIEESLTEFTEQFNQLNNQRNEDLAQGHLQLGQLDRDIRADPTAISPPDMEGQSPMAVRYRSSTQRRFSTEDVSKRLSLPMDIRLPPEFLQKLQMESPEFPKTLSRMSRRASLSDIGFGKMETYVKLDKLGEGTYATVFKGRSKLTENLVALKEIRLEHEEGAPCTAIREVSLLKNLKHANIVTLHDIIHTERSLTLVFEYLENDLKQYLDNCGNLMSVHNVKIFMFQLLRGLSYCHERKILHRDLKPQNLLINERGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTEYSTPIDMWGVGCIHYEMVTGRPMFPGSTVKEELHLIFRLLGTPTEDTWPGITSNEEFRAYNFTQYRAQPLINHAPRLDSDGIDLLMNLLLYEAKSRISAEVALRHPYFKSLGERVHVLPDNVSIFSLKEIQLQKDPGYRGSAFQQSARGKNRRQSIF", "length": 500, "header": "tr|A0A8V1A1N2-1|A0A8V1AC40_CHICK Computationally mapped isoform of cyclin-dependent kinase OS=Gallus gallus OX=9031 GN=CDK18 PE=1 SV=1 CANONICAL=A0A8V1AC40-1" }, "locus": { "chromosome": "26", "start_pos": 2207343, "end_pos": 2196776, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065342.1", "url": "https://www.ensembl.org/id/ENSGALT00010065342.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039774.1", "url": "https://www.ensembl.org/id/ENSGALP00010039774.1" } ] } }, { "isoform_ac": "A0A8V1A6P5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC40/entry#A0A8V1A6P5-1", "sequence": { "sequence": "MLCKGLPRSHSTLRRAEAKQHLPGIGSRMGSLGQLQSLDSRGKMNKMKNFKRRFSLSVPRTETIEESLTEFTEQFNQLNNQRNEDLAQGHLQLGQLDRDIRADPTAISPPDMEGQSPMAVRYRSSTQRRFSTEDVSKRLSLPMDIRLPPEFLQKLQMESPEFPKTLSRMSRRASLSDIGFGKMETYVKLDKLGEGTYATVFKGRSKLTENLVALKEIRLEHEEGAPCTAIREVSLLKNLKHANIVTLHDIIHTERSLTLVFEYLENDLKQYLDNCGNLMSVHNVKIFMFQLLRGLSYCHERKILHRDLKPQNLLINERGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTEYSTPIDMWGVGCIHYEMVTGRPMFPGSTVKEELHLIFRLLGTPTEDTWPGITSNEEFRAYNFTQYRAQPLINHAPRLDSDGIDLLMNLLLYEAKSRISAEVALRHPYFKSLGERVHVLPDNVSIFSLKEIQLQKDPGYRGSAFQQSARGKNRRQSIF", "length": 516, "header": "tr|A0A8V1A6P5-1|A0A8V1AC40_CHICK Computationally mapped isoform of cyclin-dependent kinase OS=Gallus gallus OX=9031 GN=CDK18 PE=1 SV=1 CANONICAL=A0A8V1AC40-1" }, "locus": { "chromosome": "26", "start_pos": 2207343, "end_pos": 2187726, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065346.1", "url": "https://www.ensembl.org/id/ENSGALT00010065346.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039776.1", "url": "https://www.ensembl.org/id/ENSGALP00010039776.1" } ] } }, { "isoform_ac": "A0A8V1AC36-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC40/entry#A0A8V1AC36-1", "sequence": { "sequence": "MHSMTPSSRGKMNKMKNFKRRFSLSVPRTETIEESLTEFTEQFNQLNNQRNEDLAQGHLQLGQLDRDIRADPTAISPPDMEGQSPMAVRYRSSTQRRFSTEDVSKRLSLPMDIRLPPEFLQKLQMESPEFPKTLSRMSRRASLSDIGFGKMETYVKLDKLGEGTYATVFKGRSKLTENLVALKEIRLEHEEGAPCTAIREVSLLKNLKHANIVTLHDIIHTERSLTLVFEYLENDLKQYLDNCGNLMSVHNVKIFMFQLLRGLSYCHERKILHRDLKPQNLLINERGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTEYSTPIDMWGVGCIHYEMVTGRPMFPGSTVKEELHLIFRLLGTPTEDTWPGITSNEEFRAYNFTQYRAQPLINHAPRLDSDGIDLLMNLLLYEAKSRISAEVALRHPYFKSLGERVHVLPDNVSIFSLKEIQLQKDPGYRGSAFQQSARGKNRRQSIF", "length": 484, "header": "tr|A0A8V1AC36-1|A0A8V1AC36_CHICK Computationally mapped isoform of cyclin-dependent kinase OS=Gallus gallus OX=9031 GN=CDK18 PE=1 SV=1 CANONICAL=A0A8V1AC40-1" }, "locus": { "chromosome": "26", "start_pos": 2207343, "end_pos": 2198680, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065340.1", "url": "https://www.ensembl.org/id/ENSGALT00010065340.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039772.1", "url": "https://www.ensembl.org/id/ENSGALP00010039772.1" } ] } }, { "isoform_ac": "A0A8V1AC40-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC40/entry#A0A8V1AC40-1", "sequence": { "sequence": "MNKMKNFKRRFSLSVPRTETIEESLTEFTEQFNQLNNQRNEDLAQGHLQLGQLDRDIRADPTAISPPDMEGQSPMAVRYRSSTQRRFSTEDVSKRLSLPMDIRLPPEFLQKLQMESPEFPKTLSRMSRRASLSDIGFGKMETYVKLDKLGEGTYATVFKGRSKLTENLVALKEIRLEHEEGAPCTAIREVSLLKNLKHANIVTLHDIIHTERSLTLVFEYLENDLKQYLDNCGNLMSVHNVKIFMFQLLRGLSYCHERKILHRDLKPQNLLINERGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTEYSTPIDMWGVGCIHYEMVTGRPMFPGSTVKEELHLIFRLLGTPTEDTWPGITSNEEFRAYNFTQYRAQPLINHAPRLDSDGIDLLMNLLLYEAKSRISAEVALRHPYFKSLGERVHVLPDNVSIFSLKEIQLQKDPGYRGSAFQQSARGKNRRQSIF", "length": 473, "header": "tr|A0A8V1AC40-1|A0A8V1AC40_CHICK Isoform 1 of cyclin-dependent kinase OS=Gallus gallus OX=9031 GN=CDK18 PE=1 SV=1 CANONICAL=A0A8V1AC40-1" }, "locus": { "chromosome": "26", "start_pos": 2207343, "end_pos": 2198846, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065350.1", "url": "https://www.ensembl.org/id/ENSGALT00010065350.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039777.1", "url": "https://www.ensembl.org/id/ENSGALP00010039777.1" } ] } }, { "isoform_ac": "E1C3N0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC40/entry#E1C3N0-1", "sequence": { "sequence": "MQRGAAVCSSSRGKMNKMKNFKRRFSLSVPRTETIEESLTEFTEQFNQLNNQRNEDLAQGHLQLGQLDRDIRADPTAISPPDMEGQSPMAVRYRSSTQRRFSTEDVSKRLSLPMDIRLPPEFLQKLQMESPEFPKTLSRMSRRASLSDIGFGKMETYVKLDKLGEGTYATVFKGRSKLTENLVALKEIRLEHEEGAPCTAIREVSLLKNLKHANIVTLHDIIHTERSLTLVFEYLENDLKQYLDNCGNLMSVHNVKIFMFQLLRGLSYCHERKILHRDLKPQNLLINERGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTEYSTPIDMWGVGCIHYEMVTGRPMFPGSTVKEELHLIFRLLGTPTEDTWPGITSNEEFRAYNFTQYRAQPLINHAPRLDSDGIDLLMNLLLYEAKSRISAEVALRHPYFKSLGERVHVLPDNVSIFSLKEIQLQKDPGYRGSAFQQSARGKNRRQSIF", "length": 487, "header": "tr|E1C3N0-1|A0A8V1AC40_CHICK Computationally mapped isoform of cyclin-dependent kinase OS=Gallus gallus OX=9031 GN=CDK18 PE=1 SV=3 CANONICAL=A0A8V1AC40-1" }, "locus": { "chromosome": "26", "start_pos": 2207343, "end_pos": 2193281, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065344.1", "url": "https://www.ensembl.org/id/ENSGALT00010065344.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039775.1", "url": "https://www.ensembl.org/id/ENSGALP00010039775.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:771736", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:771736", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "E7F9R5-1", "protein_name": "cyclin-dependent kinase", "gene_name": "cdk18", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNKMKNFKRRFSLSVPRTETIEENEFTEQINQLNIRCNDGVVPNSLGLHSLQPSPVAPDSQAQSPTQLQYRNKVQHRRFSMEDVTKRMSLPMDIRLPPEFLKKLQMESPPPCKPLSRMSRRASLSDIGFGKLETYVKLGKLGEGTYATVFKGRSKLTENLVALKEIRLEHEEGAPCTAIREVSLLKNLKHANIVTLHDIIHTDRCLTLVFEYLDSDLKQYLDNCGNLMSMHNVKIFMFQLLRGLSYCHKRKILHRDLKPQNLLINDKGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTEYSTPIDMWGVGCILYEMATGRPMFPGSTVKEELHLIFRLMGTPTEESWPGITANEEFKSYLFPQYRAQALINHVPRLDTEGIDLLTALLLYDTKRRISAELSLRHSYFQTLGENILSIPDTSSVFSLREIQLQKDPGHRSSVFQPPGRGKNRRQSIF", "length": 465 }, "evidence": [ { "id": "A0A8V1AC40", "url": "https://omabrowser.org/oma/group/A0A8V1AC40/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "O35832-1", "protein_name": "Cyclin-dependent kinase 18", "gene_name": "Cdk18", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNKMKNFKRRLSLSVPRPETIEESLTEFTEQFNQLHTQRNEDGRDEPGQLSPGVQYQQRQNQRRFSMEDLNKRLSLPMDIRLPQEFLQKLQLENPGLPKPLTRMSRRASLSDIGFGKLETYVKLDKLGEGTYATVFKGRSKLTENLVALKEIRLEHEEGAPCTAIREVSLLKDLKHANIVTLHDLIHTDRSLTLVFEYLDSDLKQYLDHCGNLMNMHNVKIFMFQLLRGLAYCHRRKILHRDLKPQNLLINERGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTEYSTPIDMWGVGCILYEMATGKPLFPGSTVKEELHLIFRLLGTPTEESWPGVTSISEFRAYNFPRYLPQPLLSHAPRLDTEGINLLTSLLLYESKSRMSAEAALSHPYFQSLGERVHQLDDTASIFSLKEIQLQKDPGYRGLAFQHPGRGKSRRQSIF", "length": 451 }, "evidence": [ { "id": "A0A8V1AC40", "url": "https://omabrowser.org/oma/group/A0A8V1AC40/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q04899-1", "protein_name": "Cyclin-dependent kinase 18", "gene_name": "Cdk18", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNKMKNFKRRLSLSVPRPETIEESLAEFTEQFNQLHTQTNEDGTDEPEQLSPGMQYQQRQNQRRFSMEDLNKRLSLPMDIRLPQEFLQKLQLENPGLPKPLTRMSRRASLSDIGFGKLETYVKLDKLGEGTYATVFKGRSKLTENLVALKEIRLEHEEGAPCTAIREVSLLKDLKHANIVTLHDLIHTDRSLTLVFEYLDSDLKQYLDHCGNLMNMHNVKIFMFQLLRGLAYCHHRKILHRDLKPQNLLINERGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTEYSTPIDMWGVGCILYEMATGKPLFPGSTVKEELHLIFRLLGTPTEESWPGVTSISEFRAYNFPRYLPQPLLSHAPRLDTEGINLLSSLLLYESKSRMSAEAALNHPYFQSLGDRVHQLHDTASIFSLKEIQLQKDPGYRGLAFQHPGRGKSRRQSIF", "length": 451 }, "evidence": [ { "id": "A0A8V1AC40", "url": "https://omabrowser.org/oma/group/A0A8V1AC40/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q07002-2", "protein_name": "Cyclin-dependent kinase 18", "gene_name": "CDK18", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MIMNKMKNFKRRFSLSVPRTETIEESLAEFTEQFNQLHNRRNENLQLGPLGRDPPQECSTFSPTDSGEEPGQLSPGVQFQRRQNQRRFSMEDVSKRLSLPMDIRLPQEFLQKLQMESPDLPKPLSRMSRRASLSDIGFGKLETYVKLDKLGEGTYATVFKGRSKLTENLVALKEIRLEHEEGAPCTAIREVSLLKNLKHANIVTLHDLIHTDRSLTLVFEYLDSDLKQYLDHCGNLMSMHNVKIFMFQLLRGLAYCHHRKILHRDLKPQNLLINERGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTEYSTPIDMWGVGCIHYEMATGRPLFPGSTVKEELHLIFRLLGTPTEETWPGVTAFSEFRTYSFPCYLPQPLINHAPRLDTDGIHLLSSLLLYESKSRMSAEAALSHSYFRSLGERVHQLEDTASIFSLKEIQLQKDPGYRGLAFQQPGRGKNRRQSIF", "length": 474 }, "evidence": [ { "id": "A0A8V1AC40", "url": "https://omabrowser.org/oma/group/A0A8V1AC40/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AC40", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC40" } ], "pmid": "" }, { "name": "cyclin-dependent protein serine/threonine kinase activity", "id": "GO:0004693", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004693", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AC40", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC40" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AC40", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC40" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AC40", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC40" } ], "pmid": "" }, { "name": "cyclin-dependent protein kinase holoenzyme complex", "id": "GO:0000307", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000307", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AC40", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC40" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "regulation of cell cycle phase transition", "id": "GO:1901987", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901987", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AC40", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC40" } ], "pmid": "" }, { "name": "positive regulation of myelination", "id": "GO:0031643", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031643", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AC40", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC40" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 377, "end_pos": 379, "annotation": "n_glycosylation_sequon" }, { "start_pos": 437, "end_pos": 439, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "17989", "name": "", "equation": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q6U1I9-1", "A0A8V0XNJ2-1", "A0A8V0ZUL0-1", "A0A8V0ZT63-1", "A0A8V1ACW2-1", "A0A8V0Z1X0-1", "A0A8V0YHN2-1", "A0A8V0YMN5-1", "A0A8V0Z807-1", "A0A8V0Z930-1", "A0A8V0YFR6-1", "A0A1D5P0M9-1", "A0A8V0ZBN6-1", "A0A3Q2U9U9-1", "A0A8V0YXZ5-1", "A0A8V0ZSP4-1", "A0A8V0ZXQ9-1", "A0A8V0ZZV3-1", "A0A8V1ADF0-1", "A0A8V0ZFT3-1", "A0A8V0ZA45-1", "A0A8V0ZB33-1", "A0A8V0ZD70-1", "A0A8V0Z8T4-1", "R4GIN8-1", "A0A8V0ZK64-1", "A0A8V0ZC16-1", "A0A8V0ZWW1-1", "E1BY69-1", "A0A8V0ZDW9-1", "A0A8V0ZKA2-1", "A0A3Q3B2F1-1", "F1P356-1", "A0A8V1AHA8-1", "Q8QFP8-1", "F1P011-1", "A0A8V0YKK3-1", "A0A1D5NWT4-1", "A0A1D5PMQ7-1", "E1BWA3-1", "F1NVF2-1", "A0A1D5PXN4-1", "A0A3Q2TY19-1", "A0A3Q2U592-1", "A0A8V0XCV5-1", "A0A1D5P8A9-1", "A0A1D5PMG2-1", "A0A8V0X1Q7-1", "A0A8V0Y935-1", "A0A8V0YM96-1", "A0A8V0YF83-1", "A0A8V0YJP9-1", "A0A8V1AKW4-1", "A0A8V0ZSB4-1", "F1NBT0-1", "P18652-1", "P21868-1", "P21869-1", "P53666-1", "P79996-1", "Q5F3W3-1", "Q5ZJS0-1", "Q5ZKN1-1", "Q5ZLL1-1", "A0A8V0XCS0-1", "A0A8V0XNK8-1", "A0A8V0XLV6-1", "A0A8V0XDR5-1", "E1BYH2-1", "E1BQN6-1", "A0A8V0XU71-1", "Q5ZJH6-1", "A0A8V0Y3D1-1", "A0A8V0Y7C3-1", "A0A8V0YCY4-1", "A0A8V0YIV6-1", "A0A8V0YK18-1", "A0A8V0YM22-1", "A0A8V0YTN5-1", "A0A8V0YTP2-1", "Q5F3L1-1", "A0A8V0Y3L2-1", "A0A8V0YCY8-1", "A0A8V0Y9Q1-1", "A0A8V0ZD48-1", "A0A8V0ZD60-1", "A0A8V0ZBZ2-1", "A0A8V0Z9J0-1", "A0A8V1ABF3-1", "Q8AYC9-1", "A0A8V0Z927-1", "A0A8V1A2T9-1", "Q5ZKI0-1", "Q7T0B1-1", "P10741-1", "A0A8V0YFH4-1", "E1C848-1", "A0A8V0X8M1-1", "E1BW33-1", "A0A8V0Z283-1", "A0A8V0Z157-1", "A0A3Q2U4X3-1", "A0A8V0XW11-1", "E1BUG0-1", "A0A8V1ABP4-1", "A0A8V1AJA4-1", "A0A8V1AEH4-1", "F1NJH1-1", "A0A8V1AMK5-1", "A0A3Q2TRY2-1", "A0A8V0X3D6-1", "A0A1D5PD64-1", "A0A8V0XQ97-1", "R4GJB8-1", "A0A8V0X5Z8-1", "A0A8V0XG21-1", "A0A8V0XB58-1", "A0A8V0XMX8-1", "A0A8V0XQS0-1", "A0A8V0XW29-1", "A0A8V0Y074-1", "A0A8V0XXB8-1", "A0A8V0XQ14-1", "A0A8V0XMT1-1", "A0A8V0Y457-1", "A0A8V0Y823-1", "A0A8V0Y4L8-1", "A0A8V0XND6-1", "A0A8V0YZ74-1", "A0A8V0YTI1-1", "A0A8V0YLV1-1", "A0A8V0Z2E3-1", "A0A8V0YCV9-1", "A0A8V0YSH3-1", "A0A8V0YYX2-1", "A0A8V0YZY4-1", "Q5ZIU3-1", "A0A8V0YZK0-1", "A0A8V0ZKM9-1", "A0A8V0ZWC7-1", "A0A8V1A1Y7-1", "A0A8V1A069-1", "A0A8V0ZI32-1", "A0A8V0ZH91-1", "E1BQV7-1", "A0A8V0ZRX1-1", "A0A8V0ZUU9-1", "A0A8V1A0Y8-1", "A0A8V1A7E9-1", "A0A8V1A7E0-1", "A0A8V1A3T8-1", "A0A8V1A9S5-1", "A0A8V1A7M0-1", "A0A8V1A675-1", "A0A8V1A1P3-1", "A0A8V1ADT4-1", "E1BWT0-1", "A0A8V1ACF6-1", "A0A8V1ADN9-1", "A0A8V1AM12-1", "A0A8V1A4Q4-1", "Q90891-1", "A0A1D5P517-1", "F1NB57-1", "F1NUX4-1", "A0A8V0ZZE4-1", "P05625-1", "P13863-1", "P67962-1", "Q04982-2", "Q0GGW5-1", "Q6XUX0-1", "Q8QGX4-1", "Q9I9E0-1", "Q9IA88-1", "Q5ZJK4-1", "A0A1D5PTJ8-1", "E1C2I2-1", "F1NCX7-1", "F1NKW3-1", "A0A8V1A0W4-1", "A0A8V1A4J8-1", "A0A8V1ACK0-1", "F1NCY7-1", "A0A8V0X6T4-1", "A0A8V0ZFM2-1", "A0A8V0XUM6-1", "A0A8V0XEA3-1", "A0A8V1AIY7-1", "A0A8V0YHH2-1", "A0A3Q2UI52-1", "A0A8V0ZZK5-1", "A0A8V0ZPX2-1", "A0A8V1ACB5-1", "A0A8V0YDH4-1", "A0A8V1AFS4-1", "A0A8V1AH12-1", "A0A8V0YRC9-1", "A0A8V0ZQT5-1", "A0A8V0ZFP1-1", "E1C764-1", "A0A1D5PUY5-1", "F1P4G3-1", "A0A8V0ZMK1-1", "A0A8V0Y2I5-1", "A0A8V0ZLU3-1", "A0A8V0ZNP7-1", "A0A8V0Z2Z3-1", "A0A8V0YNI5-1", "Q90771-1", "A0A8V0X4P0-1", "A0A8V0X7R2-1", "A0A3Q3A664-1", "A0A8V0YGW2-1", "E1C581-1", "A0A8V1AC40-1", "A0A3Q2TUS7-1", "A0A1D5PA08-1", "A0A8V0XFW1-1", "A0A8V0XAH9-1", "A0A8V1A4A1-1", "A0A8V0ZD40-1", "A0A8V0Z6T1-1", "A0A8V1A4V7-1", "E1C093-1", "A0A8V0YZF2-1", "E1BX69-1", "A0A8V0XI18-1", "A0A8V0Y955-1", "A0A1D5PB73-1", "A0A1D5PV76-1", "A0A1D5PX90-1", "A0A1L1RWI9-1", "A0A3Q2TV19-1", "A0A3Q2UF44-1", "A0A8V0X4Q3-1", "A0A8V0Z124-1", "A0A8V0Z6K4-1", "A0A8V1AE45-1", "A0A8V0YZV9-1", "A0A8V0YYZ3-1", "A0A8V0ZUC6-1", "A0A8V0ZUU8-1", "A0A8V1AG70-1", "F1NA68-1", "F1NLR7-1", "A0A8V0Y6K1-1", "A0A8V0XS42-1", "A0A8V0YRN4-1", "A0A8V0YFP8-1", "A0A8V1A7P9-1", "A0A1D5PRN8-1", "A0A3Q3AAD7-1", "A0A3Q2TWZ8-1", "A0A8V0XBZ0-1", "A0A8V0XFX2-1", "A0A8V0YFL1-1", "A0A8V0YTL9-1", "A0A8V0YMB3-1", "A0A8V0X2Y2-1", "A0A8V0XCY6-1", "A0A3Q2UI62-1", "A0A8V0Y241-1", "A0A8V0Z8G2-1", "A0A8V1ABR8-1", "A0A8V1AP60-1", "A0A8V0YZM1-1", "A0A8V0ZB38-1", "A0A8V0Z466-1", "A0A8V0ZA06-1", "A0A8V1AMQ2-1", "A0A8V0ZGY3-1", "A0A8V0ZQJ2-1", "A0A8V0ZYU6-1", "A0A8V1A513-1", "A0A8V0XE48-1", "A0A8V0XQQ4-1", "A0A8V0XKG0-1" ], "evidence": [ { "id": "17989", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/17989" } ] }, { "id": "46608", "name": "", "equation": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A1D5PUY5-1", "Q6U1I9-1", "A0A8V0XNJ2-1", "A0A8V0ZUL0-1", "A0A8V0ZT63-1", "A0A8V1ACW2-1", "A0A8V0Z1X0-1", "A0A8V0YHN2-1", "A0A8V0YMN5-1", "A0A8V0Z807-1", "A0A8V0Z930-1", "A0A8V0YFR6-1", "A0A1D5P0M9-1", "A0A8V0ZBN6-1", "A0A3Q2U9U9-1", "A0A8V0YRC9-1", 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"evidence": [ { "id": "46608", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/46608" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5NWT4", "gene_name": "RPS6KA3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5NWT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NWT4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5NWT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NWT4" } ] } ] }, { "uniprot_ac": "A0A1D5P0M9", "gene_name": "MAP3K13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5P0M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P0M9" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A1D5P0M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P0M9" } ] } ] }, { "uniprot_ac": "A0A1D5P517", "gene_name": "PLK3", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5P517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P517" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A1D5P517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P517" } ] } ] }, { "uniprot_ac": "A0A1D5P8A9", "gene_name": "SNRK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5P8A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P8A9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5P8A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P8A9" } ] } ] }, { "uniprot_ac": "A0A1D5PA08", "gene_name": "STK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PA08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PA08" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5PA08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PA08" } ] } ] }, { "uniprot_ac": "A0A1D5PB73", "gene_name": "CASK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PB73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PB73" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5PB73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PB73" } ] } ] }, { 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[ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PMQ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMQ7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5PMQ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMQ7" } ] } ] }, { "uniprot_ac": "A0A1D5PRN8", "gene_name": "DAPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PRN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRN8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5PRN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRN8" } ] } ] }, { "uniprot_ac": "A0A1D5PTJ8", "gene_name": "MAP3K5", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PTJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PTJ8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A1D5PTJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PTJ8" } ] } ] }, { "uniprot_ac": "A0A1D5PUY5", "gene_name": "PRKCB", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PUY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUY5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A1D5PUY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUY5" } ] } ] }, { "uniprot_ac": "A0A1D5PV76", "gene_name": "STK17A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PV76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PV76" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5PV76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PV76" } ] } ] }, { "uniprot_ac": "A0A1D5PX90", "gene_name": "KSR2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PX90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PX90" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5PX90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PX90" } ] } ] }, { "uniprot_ac": "A0A1D5PXN4", "gene_name": "PRKCD", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PXN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PXN4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A1D5PXN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PXN4" } ] } ] }, { "uniprot_ac": "A0A1L1RWI9", "gene_name": "CAMK4", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1L1RWI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RWI9" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A1L1RWI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RWI9" } ] } ] }, { "uniprot_ac": "A0A3Q2TRY2", "gene_name": "TAOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2TRY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TRY2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q2TRY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TRY2" } ] } ] }, { "uniprot_ac": "A0A3Q2TUS7", "gene_name": "TLK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2TUS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TUS7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q2TUS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TUS7" } ] } ] }, { "uniprot_ac": "A0A3Q2TV19", "gene_name": "UHMK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2TV19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TV19" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q2TV19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TV19" } ] } ] }, { "uniprot_ac": "A0A3Q2TWZ8", "gene_name": "MAP3K20", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2TWZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TWZ8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A3Q2TWZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TWZ8" } ] } ] }, { "uniprot_ac": "A0A3Q2TY19", "gene_name": "MAPK8", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2TY19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TY19" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A3Q2TY19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TY19" } ] } ] }, { "uniprot_ac": "A0A3Q2U4X3", "gene_name": "AKT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2U4X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U4X3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q2U4X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U4X3" } ] } ] }, { "uniprot_ac": "A0A3Q2U592", "gene_name": "DCLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2U592", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U592" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q2U592", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U592" } ] } ] }, { "uniprot_ac": "A0A3Q2U9U9", "gene_name": "OXSR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2U9U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U9U9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q2U9U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U9U9" } ] } ] }, { "uniprot_ac": "A0A3Q2UF44", "gene_name": "NEK8", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2UF44", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UF44" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q2UF44", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UF44" } ] } ] }, { "uniprot_ac": "A0A3Q2UI52", "gene_name": "LATS2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2UI52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UI52" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q2UI52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UI52" } ] } ] }, { "uniprot_ac": "A0A3Q2UI62", "gene_name": "CDK10", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2UI62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UI62" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A3Q2UI62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UI62" } ] } ] }, { "uniprot_ac": "A0A3Q3A664", "gene_name": "CDK17", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q3A664", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3A664" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A3Q3A664", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3A664" } ] } ] }, { "uniprot_ac": "A0A3Q3AAD7", "gene_name": "STK35", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q3AAD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3AAD7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q3AAD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3AAD7" } ] } ] }, { "uniprot_ac": "A0A3Q3B2F1", "gene_name": "PKN3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q3B2F1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3B2F1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A3Q3B2F1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3B2F1" } ] } ] }, { "uniprot_ac": "A0A8V0X1Q7", "gene_name": "MELK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X1Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X1Q7" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X1Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X1Q7" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0X1Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X1Q7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0X1Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X1Q7" } ] } ] }, { "uniprot_ac": "A0A8V0X2Y2", "gene_name": "MAPK12", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X2Y2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X2Y2" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0X2Y2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X2Y2" } ] } ] }, { "uniprot_ac": "A0A8V0X3D6", "gene_name": "LOC100858386", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X3D6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X3D6" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0X3D6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X3D6" } ] } ] }, { "uniprot_ac": "A0A8V0X4P0", "gene_name": "CDKL5", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X4P0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X4P0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0X4P0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X4P0" } ] } ] }, { "uniprot_ac": "A0A8V0X4Q3", "gene_name": "ICK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X4Q3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X4Q3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0X4Q3", "database": "UniProtKB", "url": 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"uniprot_ac": "A0A8V0X7R2", "gene_name": "SBK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X7R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X7R2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0X7R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X7R2" } ] } ] }, { "uniprot_ac": "A0A8V0X8M1", "gene_name": "TRIO", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X8M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X8M1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0X8M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X8M1" } ] } ] }, { "uniprot_ac": "A0A8V0XAH9", "gene_name": "NEK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XAH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XAH9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XAH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XAH9" } ] } ] }, { "uniprot_ac": "A0A8V0XB58", "gene_name": "CAMK2D", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XB58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XB58" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V0XB58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XB58" } ] } ] }, { "uniprot_ac": "A0A8V0XBZ0", "gene_name": "STK32C", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XBZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XBZ0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XBZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XBZ0" } ] } ] }, { "uniprot_ac": "A0A8V0XCS0", "gene_name": "PRKG2", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XCS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCS0" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0A8V0XCS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCS0" } ] } ] }, { "uniprot_ac": "A0A8V0XCV5", "gene_name": "MAP3K7", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XCV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCV5" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0XCV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCV5" } ] } ] }, { "uniprot_ac": "A0A8V0XCY6", "gene_name": "TTK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XCY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCY6" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V0XCY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCY6" } ] } ] }, { "uniprot_ac": "A0A8V0XDR5", "gene_name": "IRAK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XDR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XDR5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XDR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XDR5" } ] } ] }, { "uniprot_ac": "A0A8V0XE48", "gene_name": "ROCK2", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XE48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XE48" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "A0A8V0XE48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XE48" } ] } ] }, { "uniprot_ac": "A0A8V0XEA3", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XEA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEA3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XEA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEA3" } ] } ] }, { "uniprot_ac": "A0A8V0XFW1", "gene_name": "SGK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XFW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFW1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XFW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFW1" } ] } ] }, { "uniprot_ac": "A0A8V0XFX2", "gene_name": "NEK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XFX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFX2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XFX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFX2" } ] } ] }, { "uniprot_ac": "A0A8V0XG21", "gene_name": "LOC107050335", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XG21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XG21" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XG21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XG21" } ] } ] }, { "uniprot_ac": "A0A8V0XI18", "gene_name": "ATM", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XI18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XI18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XI18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XI18" } ] } ] }, { "uniprot_ac": "A0A8V0XKG0", "gene_name": "NEK9", "activity": [ { "ec_number": "2.7.11.38", "activity": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XKG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XKG0" } ] }, { "ec_number": "2.7.11.38", "activity": "", "evidence": [ { "id": "A0A8V0XKG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XKG0" } ] } ] }, { "uniprot_ac": "A0A8V0XLV6", "gene_name": "MAPK10", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XLV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLV6" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0XLV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLV6" } ] } ] }, { "uniprot_ac": "A0A8V0XMT1", "gene_name": "MOS", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XMT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMT1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XMT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMT1" } ] } ] }, { "uniprot_ac": "A0A8V0XMX8", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMX8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMX8" } ] } ] }, { "uniprot_ac": "A0A8V0XND6", "gene_name": "RIOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XND6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XND6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XND6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XND6" } ] } ] }, { "uniprot_ac": "A0A8V0XNJ2", "gene_name": "CDK8", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] } ] }, { "uniprot_ac": "A0A8V0XNK8", "gene_name": "PRKCQ", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XNK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNK8" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0XNK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNK8" } ] } ] }, { "uniprot_ac": "A0A8V0XQ14", "gene_name": "PLK4", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQ14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ14" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A8V0XQ14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ14" } ] } ] }, { "uniprot_ac": "A0A8V0XQ97", "gene_name": "CDK14", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQ97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ97" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0XQ97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ97" } ] } ] }, { "uniprot_ac": "A0A8V0XQQ4", "gene_name": "NME7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQQ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQQ4" } ] } ] }, { "uniprot_ac": "A0A8V0XQS0", "gene_name": "STK24", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQS0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XQS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQS0" } ] } ] }, { "uniprot_ac": "A0A8V0XS42", "gene_name": "MAP3K4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XS42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XS42" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0XS42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XS42" } ] } ] }, { "uniprot_ac": "A0A8V0XU71", "gene_name": "MYO3A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XU71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU71" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XU71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU71" } ] } ] }, { "uniprot_ac": "A0A8V0XU96", "gene_name": "PRKD1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XU96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU96" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0XU96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU96" } ] } ] }, { "uniprot_ac": "A0A8V0XUM6", "gene_name": "LATS1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XUM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XUM6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XUM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XUM6" } ] } ] }, { "uniprot_ac": "A0A8V0XW11", "gene_name": "RPS6KA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XW11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW11" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XW11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW11" } ] } ] }, { "uniprot_ac": "A0A8V0XW29", "gene_name": "CDKL2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XW29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW29" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0XW29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW29" } ] } ] }, { "uniprot_ac": "A0A8V0XXB8", "gene_name": "MAPK15", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XXB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXB8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0XXB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXB8" } ] } ] }, { "uniprot_ac": "A0A8V0Y074", "gene_name": "NEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y074", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y074" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y074", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y074" } ] } ] }, { "uniprot_ac": "A0A8V0Y241", "gene_name": "LOC426385", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y241", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y241" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y241", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y241" } ] } ] }, { "uniprot_ac": "A0A8V0Y2I5", "gene_name": "CDK7", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] } ] }, { "uniprot_ac": "A0A8V0Y3D1", "gene_name": "LRRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y3D1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3D1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y3D1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3D1" } ] } ] }, { "uniprot_ac": "A0A8V0Y3L2", "gene_name": "MLK4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y3L2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3L2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0Y3L2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3L2" } ] } ] }, { "uniprot_ac": "A0A8V0Y457", "gene_name": "PRPF4B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y457", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y457" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y457", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y457" } ] } ] }, { "uniprot_ac": "A0A8V0Y4L8", "gene_name": "HUNK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y4L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y4L8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y4L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y4L8" } ] } ] }, { "uniprot_ac": "A0A8V0Y6K1", "gene_name": "MAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6K1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6K1" } ] } ] }, { "uniprot_ac": "A0A8V0Y7C3", "gene_name": "DAPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y7C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7C3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y7C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7C3" } ] } ] }, { "uniprot_ac": "A0A8V0Y823", "gene_name": "SRPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y823", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y823" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y823", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y823" } ] } ] }, { "uniprot_ac": "A0A8V0Y8X9", "gene_name": "PRKACA", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y8X9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8X9" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0A8V0Y8X9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8X9" } ] } ] }, { "uniprot_ac": "A0A8V0Y935", "gene_name": "MAST4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y935", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y935" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y935", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y935" } ] } ] }, { "uniprot_ac": "A0A8V0Y955", "gene_name": "PAK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y955", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y955" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y955", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y955" } ] } ] }, { "uniprot_ac": "A0A8V0Y9Q1", "gene_name": "LOC107055388", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y9Q1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9Q1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y9Q1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9Q1" } ] } ] }, { "uniprot_ac": "A0A8V0YCV9", "gene_name": "SIK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YCV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YCV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCV9" } ] } ] }, { "uniprot_ac": "A0A8V0YCY4", "gene_name": "AURKB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YCY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YCY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY4" } ] } ] }, { "uniprot_ac": "A0A8V0YCY8", "gene_name": "RIOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YCY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YCY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY8" } ] } ] }, { "uniprot_ac": "A0A8V0YDH4", "gene_name": "ALPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YDH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDH4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YDH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDH4" } ] } ] }, { "uniprot_ac": "A0A8V0YF83", "gene_name": "WNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YF83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF83" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YF83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF83" } ] } ] }, { "uniprot_ac": "A0A8V0YFH4", "gene_name": "NRK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFH4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YFH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFH4" } ] } ] }, { "uniprot_ac": "A0A8V0YFL1", "gene_name": "CDK19", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0YFL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL1" } ] } ] }, { "uniprot_ac": "A0A8V0YFP8", "gene_name": "RIPK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFP8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YFP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFP8" } ] } ] }, { "uniprot_ac": "A0A8V0YFR6", "gene_name": "TNIK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFR6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YFR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFR6" } ] } ] }, { "uniprot_ac": "A0A8V0YGW2", "gene_name": "STK32B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YGW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGW2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YGW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGW2" } ] } ] }, { "uniprot_ac": "A0A8V0YHH2", "gene_name": "STK38L", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YHH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHH2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YHH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHH2" } ] } ] }, { "uniprot_ac": "A0A8V0YHN2", "gene_name": "RPS6KA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YHN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YHN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN2" } ] } ] }, { "uniprot_ac": "A0A8V0YIV6", "gene_name": "DYRK1A", "activity": [ { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] } ] }, { "uniprot_ac": "A0A8V0YJP9", "gene_name": "RIOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YJP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YJP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP9" } ] } ] }, { "uniprot_ac": "A0A8V0YK18", "gene_name": "CDC42BPB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YK18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YK18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK18" } ] } ] }, { "uniprot_ac": "A0A8V0YKK3", "gene_name": "MAP4K4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKK3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKK3" } ] } ] }, { "uniprot_ac": "A0A8V0YLV1", "gene_name": "MARK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YLV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLV1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YLV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLV1" } ] } ] }, { "uniprot_ac": "A0A8V0YM22", "gene_name": "MYO3AL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YM22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM22" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YM22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM22" } ] } ] }, { "uniprot_ac": "A0A8V0YM96", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YM96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM96" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YM96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM96" } ] } ] }, { "uniprot_ac": "A0A8V0YMB3", "gene_name": "STK32A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMB3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMB3" } ] } ] }, { "uniprot_ac": "A0A8V0YMN5", "gene_name": "BRAF", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YMN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YMN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN5" } ] } ] }, { "uniprot_ac": "A0A8V0YNI5", "gene_name": "NIM1K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YNI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNI5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YNI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNI5" } ] } ] }, { "uniprot_ac": "A0A8V0YRC9", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] } ] }, { "uniprot_ac": "A0A8V0YRN4", "gene_name": "GAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRN4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YRN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRN4" } ] } ] }, { "uniprot_ac": "A0A8V0YSH3", "gene_name": "RPS6KA6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YSH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSH3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YSH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSH3" } ] } ] }, { "uniprot_ac": "A0A8V0YTI1", "gene_name": "TSSK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTI1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTI1" } ] } ] }, { "uniprot_ac": "A0A8V0YTL9", "gene_name": "VRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTL9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTL9" } ] } ] }, { "uniprot_ac": "A0A8V0YTN5", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTN5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTN5" } ] } ] }, { "uniprot_ac": "A0A8V0YTP2", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTP2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTP2" } ] } ] }, { "uniprot_ac": "A0A8V0YXZ5", "gene_name": "CDC42BPA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YXZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXZ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YXZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXZ5" } ] } ] }, { "uniprot_ac": "A0A8V0YYX2", "gene_name": "PAK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YYX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYX2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YYX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYX2" } ] } ] }, { "uniprot_ac": "A0A8V0YYZ3", "gene_name": "SPEG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YYZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYZ3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YYZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYZ3" } ] } ] }, { "uniprot_ac": "A0A8V0YZ74", "gene_name": "MAP2K5", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZ74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZ74" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V0YZ74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZ74" } ] } ] }, { "uniprot_ac": "A0A8V0YZF2", "gene_name": "PAK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZF2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YZF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZF2" } ] } ] }, { "uniprot_ac": "A0A8V0YZK0", "gene_name": "MAP3K6", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZK0" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0YZK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZK0" } ] } ] }, { "uniprot_ac": "A0A8V0YZM1", "gene_name": "MOK", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] }, { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] } ] }, { "uniprot_ac": "A0A8V0YZV9", "gene_name": "ATR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YZV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZV9" } ] } ] }, { "uniprot_ac": "A0A8V0YZY4", "gene_name": "SBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZY4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YZY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZY4" } ] } ] }, { "uniprot_ac": "A0A8V0Z124", "gene_name": "VRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z124", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z124" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z124", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z124" } ] } ] }, { "uniprot_ac": "A0A8V0Z157", "gene_name": "MARK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] } ] }, { "uniprot_ac": "A0A8V0Z1X0", "gene_name": "MAP4K3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z1X0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1X0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z1X0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1X0" } ] } ] }, { "uniprot_ac": "A0A8V0Z283", "gene_name": "MARK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] } ] }, { "uniprot_ac": "A0A8V0Z2E3", "gene_name": "PDIK1L", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z2E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2E3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z2E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2E3" } ] } ] }, { "uniprot_ac": "A0A8V0Z2Z3", "gene_name": "AAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z2Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2Z3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z2Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2Z3" } ] } ] }, { "uniprot_ac": "A0A8V0Z466", "gene_name": "MAP3K19", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z466", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z466" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z466", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z466" } ] } ] }, { "uniprot_ac": "A0A8V0Z6K4", "gene_name": "PIK3R4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z6K4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6K4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": 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"https://www.uniprot.org/uniprotkb/A0A8V0ZKA2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZKA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKA2" } ] } ] }, { "uniprot_ac": "A0A8V0ZKM9", "gene_name": "STK36", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZKM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKM9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZKM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKM9" } ] } ] }, { "uniprot_ac": "A0A8V0ZLU3", "gene_name": "TLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZLU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLU3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZLU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLU3" } ] } ] }, { "uniprot_ac": "A0A8V0ZMK1", "gene_name": "PIKFYVE", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] }, { "ec_number": "2.7.1.150", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] }, { "ec_number": "2.7.1.150", "activity": "", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] } ] }, { "uniprot_ac": "A0A8V0ZNP7", "gene_name": "SGK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZNP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNP7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZNP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNP7" } ] } ] }, { "uniprot_ac": "A0A8V0ZPX2", "gene_name": "ALPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZPX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPX2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZPX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPX2" } ] } ] }, { "uniprot_ac": "A0A8V0ZQJ2", "gene_name": "RPS6KB2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZQJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZQJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQJ2" } ] } ] }, { "uniprot_ac": "A0A8V0ZQT5", "gene_name": "SLC13A3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZQT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQT5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZQT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQT5" } ] } ] }, { "uniprot_ac": "A0A8V0ZRX1", "gene_name": "SETD6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZRX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRX1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZRX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRX1" } ] }, { "ec_number": "2.1.1.-", "activity": "", "evidence": [ { "id": "A0A8V0ZRX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRX1" } ] } ] }, { "uniprot_ac": "A0A8V0ZSB4", "gene_name": "SIK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZSB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSB4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZSB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSB4" } ] } ] }, { "uniprot_ac": "A0A8V0ZSP4", "gene_name": "PKN2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] }, { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] } ] }, { "uniprot_ac": "A0A8V0ZT63", "gene_name": "STK25", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZT63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT63" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZT63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT63" } ] } ] }, { "uniprot_ac": "A0A8V0ZUC6", "gene_name": "PAK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUC6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUC6" } ] } ] }, { "uniprot_ac": "A0A8V0ZUL0", "gene_name": "PASK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUL0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUL0" } ] } ] }, { "uniprot_ac": "A0A8V0ZUU8", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU8" } ] } ] }, { "uniprot_ac": "A0A8V0ZUU9", "gene_name": "MKNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU9" } ] } ] }, { "uniprot_ac": "A0A8V0ZWC7", "gene_name": "EIF2AK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZWC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWC7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZWC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWC7" } ] } ] }, { "uniprot_ac": "A0A8V0ZWW1", "gene_name": "MAP3K12", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZWW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWW1" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0ZWW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWW1" } ] } ] }, { "uniprot_ac": "A0A8V0ZXQ9", "gene_name": "PRKG1", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZXQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXQ9" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0A8V0ZXQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXQ9" } ] } ] }, { "uniprot_ac": "A0A8V0ZYU6", "gene_name": "TNNI3K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZYU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYU6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZYU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYU6" } ] } ] }, { "uniprot_ac": "A0A8V0ZZE4", "gene_name": "OBSCN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZZE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZE4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZZE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZE4" } ] } ] }, { "uniprot_ac": "A0A8V0ZZK5", "gene_name": "STK38", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZZK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZK5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZZK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZK5" } ] } ] }, { "uniprot_ac": "A0A8V0ZZV3", "gene_name": "MYO3B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZZV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZV3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZZV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZV3" } ] } ] }, { "uniprot_ac": "A0A8V1A069", "gene_name": "TESK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A069", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A069" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1A069", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A069" } ] } ] }, { "uniprot_ac": "A0A8V1A0W4", "gene_name": "ULK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A0W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0W4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A0W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0W4" } ] } ] }, { "uniprot_ac": "A0A8V1A0Y8", "gene_name": "MAST2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A0Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Y8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A0Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Y8" } ] } ] }, { "uniprot_ac": "A0A8V1A1P3", "gene_name": "SRPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A1P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1P3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A1P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1P3" } ] } ] }, { "uniprot_ac": "A0A8V1A1Y7", "gene_name": "CDK2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A1Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1Y7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V1A1Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1Y7" } ] } ] }, { "uniprot_ac": "A0A8V1A2T9", "gene_name": "MAP3K14", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A2T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2T9" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V1A2T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2T9" } ] } ] }, { "uniprot_ac": "A0A8V1A3T8", "gene_name": "MAST3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A3T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3T8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A3T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3T8" } ] } ] }, { "uniprot_ac": "A0A8V1A4A1", "gene_name": "CAMKK2", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4A1" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1A4A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4A1" } ] } ] }, { "uniprot_ac": "A0A8V1A4J8", "gene_name": "MAPKAPK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4J8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A4J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4J8" } ] } ] }, { "uniprot_ac": "A0A8V1A4Q4", "gene_name": "MAPK3", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Q4" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1A4Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Q4" } ] } ] }, { "uniprot_ac": "A0A8V1A4V7", "gene_name": "HIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A4V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V7" } ] } ] }, { "uniprot_ac": "A0A8V1A513", "gene_name": "DAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A513" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A513" } ] } ] }, { "uniprot_ac": "A0A8V1A675", "gene_name": "CSNK1G2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A675", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A675" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A675", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A675" } ] } ] }, { "uniprot_ac": "A0A8V1A7E0", "gene_name": "DYRK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1A7E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E0" } ] } ] }, { "uniprot_ac": "A0A8V1A7E9", "gene_name": "SIK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E9" } ] } ] }, { "uniprot_ac": "A0A8V1A7M0", "gene_name": "STK39", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M0" } ] } ] }, { "uniprot_ac": "A0A8V1A7P9", "gene_name": "DCAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] } ] }, { "uniprot_ac": "A0A8V1A9S5", "gene_name": "NUAK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A9S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9S5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A9S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9S5" } ] } ] }, { "uniprot_ac": "A0A8V1ABF3", "gene_name": "PRKAA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] } ] }, { "uniprot_ac": "A0A8V1ABP4", "gene_name": "DSTYK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP4" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1ABP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP4" } ] } ] }, { "uniprot_ac": "A0A8V1ABR8", "gene_name": "CAMK4L", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR8" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1ABR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR8" } ] } ] }, { "uniprot_ac": "A0A8V1AC40", "gene_name": "CDK18", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AC40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC40" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V1AC40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC40" } ] } ] }, { "uniprot_ac": "A0A8V1ACB5", "gene_name": "MAPK13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACB5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1ACB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACB5" } ] } ] }, { "uniprot_ac": "A0A8V1ACF6", "gene_name": "PIM1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF6" } ] } ] }, { "uniprot_ac": "A0A8V1ACK0", "gene_name": "MAPKAPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK0" } ] } ] }, { "uniprot_ac": "A0A8V1ACW2", "gene_name": "WNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACW2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACW2" } ] } ] }, { "uniprot_ac": "A0A8V1ADF0", "gene_name": "MAP2K2", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF0" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V1ADF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF0" } ] } ] }, { "uniprot_ac": "A0A8V1ADN9", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADN9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1ADN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADN9" } ] } ] }, { "uniprot_ac": "A0A8V1ADT4", "gene_name": "MKNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADT4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ADT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADT4" } ] } ] }, { "uniprot_ac": "A0A8V1AE45", "gene_name": "ERN1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AE45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE45" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AE45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE45" } ] } ] }, { "uniprot_ac": "A0A8V1AEH4", "gene_name": "STK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEH4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEH4" } ] } ] }, { "uniprot_ac": "A0A8V1AFS4", "gene_name": "STKLD1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AFS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFS4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AFS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFS4" } ] } ] }, { "uniprot_ac": "A0A8V1AG70", "gene_name": "LOC100857512", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AG70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG70" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AG70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG70" } ] } ] }, { "uniprot_ac": "A0A8V1AH12", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AH12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH12" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AH12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH12" } ] } ] }, { "uniprot_ac": "A0A8V1AHA8", "gene_name": "NEK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AHA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHA8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AHA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHA8" } ] } ] }, { "uniprot_ac": "A0A8V1AIY7", "gene_name": "AATK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AIY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AIY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIY7" } ] } ] }, { "uniprot_ac": "A0A8V1AJA4", "gene_name": "RPS6KB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AJA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJA4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AJA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJA4" } ] } ] }, { "uniprot_ac": "A0A8V1AKW4", "gene_name": "MAP2K4", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AKW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKW4" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V1AKW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKW4" } ] } ] }, { "uniprot_ac": "A0A8V1AM12", "gene_name": "GSG2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AM12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM12" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AM12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM12" } ] } ] }, { "uniprot_ac": "A0A8V1AMK5", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AMK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V1AMK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK5" } ] } ] }, { "uniprot_ac": "A0A8V1AMQ2", "gene_name": "CAMKK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AMQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ2" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1AMQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ2" } ] } ] }, { "uniprot_ac": "A0A8V1AP60", "gene_name": "KSR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AP60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AP60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP60" } ] } ] }, { "uniprot_ac": "E1BQN6", "gene_name": "PRKCZ", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQN6" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1BQN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQN6" } ] } ] }, { "uniprot_ac": "E1BQV7", "gene_name": "SLK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQV7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BQV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQV7" } ] } ] }, { "uniprot_ac": "E1BUG0", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] } ] }, { "uniprot_ac": "E1BW33", "gene_name": "SMG1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BW33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BW33" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BW33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BW33" } ] } ] }, { "uniprot_ac": "E1BWA3", "gene_name": "PRKCI", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BWA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWA3" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1BWA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWA3" } ] } ] }, { "uniprot_ac": "E1BWT0", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BWT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWT0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BWT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWT0" } ] } ] }, { "uniprot_ac": "E1BX69", "gene_name": "EIF2AK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BX69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BX69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BX69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BX69" } ] } ] }, { "uniprot_ac": "E1BY69", "gene_name": "PIM3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BY69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BY69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY69" } ] } ] }, { "uniprot_ac": "E1BYH2", "gene_name": "TAOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BYH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYH2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BYH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYH2" } ] } ] }, { "uniprot_ac": "E1C093", "gene_name": "PIK3CG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] } ] }, { "uniprot_ac": "E1C2I2", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C2I2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2I2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C2I2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2I2" } ] } ] }, { "uniprot_ac": "E1C581", "gene_name": "TBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C581", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C581" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C581", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C581" } ] } ] }, { "uniprot_ac": "E1C6T4", "gene_name": "PRKD3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C6T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C6T4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1C6T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C6T4" } ] } ] }, { "uniprot_ac": "E1C764", "gene_name": "BMP2K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C764", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C764" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C764", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C764" } ] } ] }, { "uniprot_ac": "E1C848", "gene_name": "MAP3K8", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C848", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C848" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1C848", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C848" } ] } ] }, { "uniprot_ac": "F1NA68", "gene_name": "CDK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NA68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NA68" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1NA68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NA68" } ] } ] }, { "uniprot_ac": "F1NB57", "gene_name": "PLK2", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NB57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NB57" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "F1NB57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NB57" } ] } ] }, { "uniprot_ac": "F1NBT0", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NBT0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NBT0" } ] } ] }, { "uniprot_ac": "F1NCX7", "gene_name": "PLK1", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NCX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCX7" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "F1NCX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCX7" } ] } ] }, { "uniprot_ac": "F1NCY7", "gene_name": "MAPKAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NCY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NCY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCY7" } ] } ] }, { "uniprot_ac": "F1NJH1", "gene_name": "PRKCH", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NJH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJH1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1NJH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJH1" } ] } ] }, { "uniprot_ac": "F1NKW3", "gene_name": "MAP3K15", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NKW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NKW3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1NKW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NKW3" } ] } ] }, { "uniprot_ac": "F1NLR7", "gene_name": "CLK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NLR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLR7" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "F1NLR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLR7" } ] } ] }, { "uniprot_ac": "F1NUX4", "gene_name": "MTOR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NUX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NUX4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NUX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NUX4" } ] } ] }, { "uniprot_ac": "F1NVF2", "gene_name": "MAP2K6", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NVF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVF2" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "F1NVF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVF2" } ] } ] }, { "uniprot_ac": "F1P011", "gene_name": "CAMK2A", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1P011", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P011" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F1P011", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P011" } ] } ] }, { "uniprot_ac": "F1P356", "gene_name": "NUAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1P356", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P356" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1P356", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P356" } ] } ] }, { "uniprot_ac": "F1P4G3", "gene_name": "HIPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = 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"MNLRPGAEQKVVFITARVHPGETPSSFVCQGIIDFLVSQHPIAKVLRDHLVFKIAPMLNPDGVYLGNYRCSLMGFDLNRHWANPSPWAHPTLHGVKQLIVEMYNNPKINLEFYIDIHAHSTMMNGFMYGNIFENEERFQRQAVFPKLLCQNAEDFSYSSTSFNRDAVKAGTGRRFLGGLLNDTSYCYTLEVSFYSYIVGGTTAAVPYTEEAYMKLGRNVARTFLDYYRLNSLVERPLAATPKTRKEKLPVFKCTTQQGQGTSHADRKPEKRSQAHLKDQSLSAQ", "length": 284, "header": "tr|A0A8V1ACG5-1|A0A8V1ACG5_CHICK Computationally mapped isoform of AGBL carboxypeptidase 4 OS=Gallus gallus OX=9031 GN= PE=3 SV=1 CANONICAL=A0A8V1AEI1-1" }, "locus": { "chromosome": "8", "start_pos": 22630509, "end_pos": 22383056, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065655.1", "url": "https://www.ensembl.org/id/ENSGALT00010065655.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039921.1", "url": "https://www.ensembl.org/id/ENSGALP00010039921.1" } ] } }, { "isoform_ac": "A0A8V1AEI1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEI1/entry#A0A8V1AEI1-1", "sequence": { "sequence": "MDPPPPTVLAAPGGYLFITMNLRPGAEQKVVFITARVHPGETPSSFVCQGIIDFLVSQHPIAKVLRDHLVFKIAPMLNPDGVYLGNYRCSLMGFDLNRHWANPSPWAHPTLHGVKQLIVEMYNNPKINLEFYIDIHAHSTMMNGFMYGNIFENEERFQRQAVFPKLLCQNAEDFSYSSTSFNRDAVKAGTGRRFLGGLLNDTSYCYTLEVSFYSYIVGGTTAAVPYTEEAYMKLGRNVARTFLDYYRLNSLVERPLAATPKTRKEKLPVFKCTTQQGQGTSHADRKPEKRSQAHLKDQSLSAQ", "length": 303, "header": "tr|A0A8V1AEI1-1|A0A8V1AEI1_CHICK Isoform 1 of AGBL carboxypeptidase 4 OS=Gallus gallus OX=9031 GN= PE=3 SV=1 CANONICAL=A0A8V1AEI1-1" }, "locus": { "chromosome": "8", "start_pos": 22584921, "end_pos": 22383056, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065653.1", "url": "https://www.ensembl.org/id/ENSGALT00010065653.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039919.1", "url": "https://www.ensembl.org/id/ENSGALP00010039919.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { 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"Protein Classification", "Other" ] }, { "id": "A0A8V1A2I8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2I8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A2I8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2I8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ACY5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACY5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ACY5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACY5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRVLLGWMGPLLALLVLQPAGSMAAEVQCPVPTIPHGRLNPAQKNLTAGSAAMLECDAGYVPAGSNTVKCLSSGRLQPRAPACTLGTHGLFSWSFSHAFVWVYLLKAHQGRCPSPPAVDHADRRLSYELLVGSTVTYFCRHGYMLIPGVSPTTTCLTDFTWSAVPALCQMVQCPSPDIVNGRVTSGKQDKYSVGQQVEFQCNPGYTMWGSQRIQCWSDGNWKPPVPYCDKVCVPPPLITSGQHTGVRTELFPYGMEVKYSCAEGLSLIGDESIYCTSEDGVNLTWSGPAPVCRVVRCPRPVVAQGRMDLSRHTFSYGTSVHFSCNEGFVLHGSAESRCVADGTWQPALPECQPALCPKPQVANGKLTSTDQMWYPINATVTFECHEGYHHFSGDGEAALKDSWTATCLADGNWTPLPKCKKQGDADVCGEVAYIQSVVSDCHVPTEDVKTLLEIRKLFLEIQKLKVELQGLSKEFLEHILH", "length": 481, "header": "tr|A0A8V1ACY5-1|A0A8V1ACY5_CHICK Isoform 1 of Sushi domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1ACY5-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A2I8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACY5/entry#A0A8V1A2I8-1", "sequence": { "sequence": "MESCCCWLLEHAVNPQPPPPKLSCSPGRCPSPPAVDHADRRLSYELLVGSTVTYFCRHGYMLIPGVSPTTTCLTDFTWSAVPALCQSECSLPFALGKQDKYSVGQQVEFQCNPGYTMWGSQRIQCWSDGNWKPPVPYCDKGEPKWHFLGGSWELHLQLFPYGMEVKYSCAEGLSLIGDESIYCTSEDGVNLTWSGPAPVCRGESAEPQMDLSRHTFSYGTSVHFSCNEGFVLHGSAESRCVADGTWQPALPECQPGESSFNVWLLICRSKTTRAISPTPISGRENSAGDTKTLPGDSKTEGGIARTEQGVPGAHSALSRLPCGHSPCGQSTYKKPPRNCMVRASTHRSRSLLPCCMLEHRGVFCSNPQIGHA", "length": 372, "header": "tr|A0A8V1A2I8-1|A0A8V1ACY5_CHICK Computationally mapped isoform of Sushi domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1ACY5-1" }, "locus": { "chromosome": "26", "start_pos": 2681102, "end_pos": 2678493, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065834.1", "url": "https://www.ensembl.org/id/ENSGALT00010065834.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040100.1", "url": "https://www.ensembl.org/id/ENSGALP00010040100.1" } ] } }, { "isoform_ac": "A0A8V1ACY5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACY5/entry#A0A8V1ACY5-1", "sequence": { "sequence": "MRVLLGWMGPLLALLVLQPAGSMAAEVQCPVPTIPHGRLNPAQKNLTAGSAAMLECDAGYVPAGSNTVKCLSSGRLQPRAPACTLGTHGLFSWSFSHAFVWVYLLKAHQGRCPSPPAVDHADRRLSYELLVGSTVTYFCRHGYMLIPGVSPTTTCLTDFTWSAVPALCQMVQCPSPDIVNGRVTSGKQDKYSVGQQVEFQCNPGYTMWGSQRIQCWSDGNWKPPVPYCDKVCVPPPLITSGQHTGVRTELFPYGMEVKYSCAEGLSLIGDESIYCTSEDGVNLTWSGPAPVCRVVRCPRPVVAQGRMDLSRHTFSYGTSVHFSCNEGFVLHGSAESRCVADGTWQPALPECQPALCPKPQVANGKLTSTDQMWYPINATVTFECHEGYHHFSGDGEAALKDSWTATCLADGNWTPLPKCKKQGDADVCGEVAYIQSVVSDCHVPTEDVKTLLEIRKLFLEIQKLKVELQGLSKEFLEHILH", "length": 481, "header": "tr|A0A8V1ACY5-1|A0A8V1ACY5_CHICK Isoform 1 of Sushi domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1ACY5-1" }, "locus": { "chromosome": "26", "start_pos": 2680935, "end_pos": 2677707, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065837.1", "url": "https://www.ensembl.org/id/ENSGALT00010065837.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040103.1", "url": "https://www.ensembl.org/id/ENSGALP00010040103.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 282, "end_pos": 284, "annotation": "n_glycosylation_sequon" }, { "start_pos": 377, "end_pos": 379, "annotation": "n_glycosylation_sequon" }, { "start_pos": 412, "end_pos": 414, "annotation": "n_glycosylation_sequon" }, { "start_pos": 45, "end_pos": 47, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1ACY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACY5" }, { "id": "PS50923", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50923" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Sushi", "eco_id": "ECO_0000259", "start_pos": 27, "end_pos": 85, "start_aa": "Val", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 282, "end_pos": 284 }, { "start_pos": 377, "end_pos": 379 }, { "start_pos": 412, "end_pos": 414 }, { "start_pos": 45, "end_pos": 47 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1ADJ0-1", "uniprot_ac": "A0A8V1ADJ0", "uniprot_id": "A0A8V1ADJ0_CHICK", "mass": { "chemical_mass": 98986.0, "monoisotopic_mass": 98986.0 }, "refseq": {}, "gene_names": [ { "name": "ZNF767", "type": "recommended", "evidence": [ { "id": "A0A8V1ADJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADJ0" } ] } ], "protein_names": [ { "name": "Zinc finger family member 767", "type": "synonym", "evidence": [ { "id": "A0A8V1ADJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADJ0/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADJ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADJ0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ZNF767", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADJ0", "locus": { "chromosome": "2", "start_pos": 570939, "end_pos": 555488, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027246", "url": "https://www.ensembl.org/id/ENSGALG00010027246" } ] } } ], "crossref": [ { "id": "A0A8V1ADJ0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1ADJ0", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd07765", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07765", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "420372", "url": "https://www.ncbi.nlm.nih.gov/gene/420372", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001909", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001909", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036051", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036051", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050752", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050752", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050758", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050758", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "CMRSFSC", "url": "https://omabrowser.org/oma/group/CMRSFSC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A365", "url": "https://www.orthodb.org/?gene=A0A8V1A365", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A847", "url": "https://www.orthodb.org/?gene=A0A8V1A847", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AAR4", "url": "https://www.orthodb.org/?gene=A0A8V1AAR4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ADJ0", "url": "https://www.orthodb.org/?gene=A0A8V1ADJ0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AFK7", "url": "https://www.orthodb.org/?gene=A0A8V1AFK7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23234", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23234", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23234:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23234:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24381", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24381", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24381:SF269", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24381:SF269", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24384", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24384", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24384:SF218", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24384:SF218", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01352", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01352", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-212436", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-212436", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1A365", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A365", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A365-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A365-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A847", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A847", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A847-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A847-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AAR4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAR4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AAR4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAR4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ADJ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADJ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ADJ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADJ0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFK7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFK7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFK7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFK7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASALPGSCLCSSSLPQAPGEAVPSSTASISLWTVVAAVQAVEKSVEAHASRLLNLERRTVTTEKKYLDCEKTVVDFGNQLESKLTVLGTLIREYGQLQRRLEHMENLLKNRNFCILRLPPAPKGPEASESETACFAEQEWENLEEWQKELYRNMLRGNSESLNSLDYSVSRSDLSQLQRGEAPCSEVTSAQKEVPTEPSADFSIPEPSFTGTLKQNEEVCAEEQEATEGAEFTELSVVPADEVIAFKIEQLDSDECLQSSECPTALSGESEDMFFQSANEALPFDSQFSSPVPLGNQSLSRLVPSASGEGDLGEISTVTFYRQEYPEERPHSCAACRKGLCLKKMLMMQQQNHSTLCGGEPTEDENIFIHQPHQQIHIATESFKQNLKVKAPAGISATNKARGSSRCMKSINTNRNKPGHPQGKPYKCSKCQECFSQKKTLIIHQRVHSGRSPGVLWCSYCGKTFSHPSNLIRHQRIHTEDSSIRVKEEEESCTAAQEELEAAGAVQEPCPGQTKGGTEVYSRELPGTAREDLPGDTESQTCMTAVLSWIKQEEELQCPEQQGSEKEEIPTEPGAVHDENRRDTLADSFVSTMCDSGMLERPEEKFHKDPSPALTWDSQWGSEMMETTTSRNGFGGGAQYDRAFGEHLDLFNAQQSDVRKRLCVSSGCERNYIQQEHLSALQGAQEELLPVPKCENSPIEVAFQHPVDAAGEKFEGLPAKLAPSSAGRTRLREHNGLCREDRPSVGSRGKLPAENVLSSPCEANTRDASEAPRGGLASQQQSQGKGKSYICNDCGKSFVCHSWLVRHQTSHTSERPYKCSKCDKSYRRKDYLLKHLRRHSGEGLFPCHLCSKRFVLRRSLIKHQESHVQRTHQTAIRPCAEIKESVLHSR", "length": 891, "header": "tr|A0A8V1ADJ0-1|A0A8V1ADJ0_CHICK Isoform 1 of Zinc finger family member 767 OS=Gallus gallus OX=9031 GN=ZNF767 PE=4 SV=1 CANONICAL=A0A8V1ADJ0-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A365-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADJ0/entry#A0A8V1A365-1", "sequence": { "sequence": "MASALPGSCLCSSSLPQAPGEAVPSSTASISLWTVVAAVQAVEKSVEAHASRLLNLERRTVTTEKKYLDCEKTVVDFGNQLESKLTVLGTLIREYGQLQRRLEHMENLLKNRNFCILRLPPAPKGPEASESETACFAEQEWENLEEWQKELYRNMLRGNSESLNSLDYSVSRSDLSQLQRGEAPCSEVTSAQKEVPTEPSAADFSIPEPSFTGTLKQNEEVCAEEQEATEGAEFTELSVVPADEVIAFKIEQLDSDECLQSSECPTALSGESEDMFFQSANEALPFDSQFSSPVPLGNQSLSRLVPSASGEGDLGEISTVTFYRQEYPEERPHSCAACRKGLCLKKMLMMQQQNHSTLCGGEPTEDENIFIHQPHQQIHIATESFKQNLKVKAPAGISATNKARGSSRCMKSINTNRNKPGHPQGKPYKCSKCQECFSQKKTLIIHQRVHSGRSPGVLWCSYCGKTFSHPSNLIRHQRIHTGERPYQCNECLKRFTQKQHLLQHEKIHLRERNCAARNHTREAPL", "length": 525, "header": "tr|A0A8V1A365-1|A0A8V1ADJ0_CHICK Computationally mapped isoform of Zinc finger family member 767 OS=Gallus gallus OX=9031 GN=ZNF767 PE=4 SV=1 CANONICAL=A0A8V1ADJ0-1" }, "locus": { "chromosome": "2", "start_pos": 560986, "end_pos": 556452, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066057.1", "url": "https://www.ensembl.org/id/ENSGALT00010066057.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040323.1", "url": "https://www.ensembl.org/id/ENSGALP00010040323.1" } ] } }, { "isoform_ac": "A0A8V1A847-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADJ0/entry#A0A8V1A847-1", "sequence": { "sequence": "MASALPGSCLCSSSLPQAPGEAVPSSTASISLWTVVAAVQAVEKSVEAHASRLLNLERRTVTTEKKYLDCEKTVVDFGNQLESKLTVLGTLIREYGQLQRRLEHMENLLKNRNFCILRLPPAPKGPEASESETACFAEQEWENLEEWQKELYRNMLRGNSESLNSLDYSVSRSDLSQLQRGEAPCSEVTSAQKEVPTEPSADFSIPEPSFTGTLKQNEEVCAEEQEATEGAEFTELSVEDSSIRVKEEEESCTAAQEELEAAGAVQEPCPGQTKGGTEVYSRELPGTAREDLPGDTESQTCMTAVLSWIKQEEELQCPEQQGSEKEEIPTEPGAVLKPPIILTVSIRWLALRGHKYSFWIPLRDFLN", "length": 367, "header": "tr|A0A8V1A847-1|A0A8V1ADJ0_CHICK Computationally mapped isoform of Zinc finger family member 767 OS=Gallus gallus OX=9031 GN=ZNF767 PE=4 SV=1 CANONICAL=A0A8V1ADJ0-1" }, "locus": { "chromosome": "2", "start_pos": 568962, "end_pos": 556452, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066059.1", "url": "https://www.ensembl.org/id/ENSGALT00010066059.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040325.1", "url": "https://www.ensembl.org/id/ENSGALP00010040325.1" } ] } }, { "isoform_ac": "A0A8V1AAR4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADJ0/entry#A0A8V1AAR4-1", "sequence": { "sequence": "MASALPGSCLCSSSLPQAPGEAVPSSTASISLWTVVAAVQAVEKSVEAHASRLLNLERRTVTTEKKYLDCEKTVVDFGNQLESKLTVLGTLIREYGQLQRRLEHMENLLKNRNFCILRLPPAPKGPEASESETACFAEQEWENLEEWQKELYRNMLRGNSESLNSLDYSVSRSDLSQLQRGEAPCSEVTSAQKEVPTEPSADFSIPEPSFTGTLKQNEEVCAEEQEATEGAEFTELSVEDSSIRVKEEEESCTAAQEELEAAGAVQEPCPGQTKGGTEVYSRELPGTAREDLPGDTESQTCMTAVLSWIKQEEELQCPEQQGSEKEEIPTEPGAVHDENRRDTLADSFVSTMCDSGMLERPEEKFHKDPSPALTWDSQWGSEMMETTTSRNGFGGGAQYDRAFGEHLDLFNAQQSDVRKRLCVSSGCERNYIQQEHLSALQGAQEELLPVPKCENSPIEVAFQHPVDAAGEKFEGLPAKLAPSSAGRTRLREHNGLCREDRPSVGSRGKLPAENVLSSPCEANTRDASEAPRGGLASQQQSQGKGKSYICNDCGKSFVCHSWLVRHQTSHTSERPYKCSKCDKSYRRKDYLLKHLRRHSGEGLFPCHLCSKRFVLRRSLIKHQESHVQRTHQTAIRPCAEIKESVLHSR", "length": 649, "header": "tr|A0A8V1AAR4-1|A0A8V1ADJ0_CHICK Computationally mapped isoform of Zinc finger family member 767 OS=Gallus gallus OX=9031 GN=ZNF767 PE=4 SV=1 CANONICAL=A0A8V1ADJ0-1" }, "locus": { "chromosome": "2", "start_pos": 569935, "end_pos": 556452, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066061.1", "url": "https://www.ensembl.org/id/ENSGALT00010066061.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040327.1", "url": "https://www.ensembl.org/id/ENSGALP00010040327.1" } ] } }, { "isoform_ac": "A0A8V1ADJ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADJ0/entry#A0A8V1ADJ0-1", "sequence": { "sequence": "MASALPGSCLCSSSLPQAPGEAVPSSTASISLWTVVAAVQAVEKSVEAHASRLLNLERRTVTTEKKYLDCEKTVVDFGNQLESKLTVLGTLIREYGQLQRRLEHMENLLKNRNFCILRLPPAPKGPEASESETACFAEQEWENLEEWQKELYRNMLRGNSESLNSLDYSVSRSDLSQLQRGEAPCSEVTSAQKEVPTEPSADFSIPEPSFTGTLKQNEEVCAEEQEATEGAEFTELSVVPADEVIAFKIEQLDSDECLQSSECPTALSGESEDMFFQSANEALPFDSQFSSPVPLGNQSLSRLVPSASGEGDLGEISTVTFYRQEYPEERPHSCAACRKGLCLKKMLMMQQQNHSTLCGGEPTEDENIFIHQPHQQIHIATESFKQNLKVKAPAGISATNKARGSSRCMKSINTNRNKPGHPQGKPYKCSKCQECFSQKKTLIIHQRVHSGRSPGVLWCSYCGKTFSHPSNLIRHQRIHTEDSSIRVKEEEESCTAAQEELEAAGAVQEPCPGQTKGGTEVYSRELPGTAREDLPGDTESQTCMTAVLSWIKQEEELQCPEQQGSEKEEIPTEPGAVHDENRRDTLADSFVSTMCDSGMLERPEEKFHKDPSPALTWDSQWGSEMMETTTSRNGFGGGAQYDRAFGEHLDLFNAQQSDVRKRLCVSSGCERNYIQQEHLSALQGAQEELLPVPKCENSPIEVAFQHPVDAAGEKFEGLPAKLAPSSAGRTRLREHNGLCREDRPSVGSRGKLPAENVLSSPCEANTRDASEAPRGGLASQQQSQGKGKSYICNDCGKSFVCHSWLVRHQTSHTSERPYKCSKCDKSYRRKDYLLKHLRRHSGEGLFPCHLCSKRFVLRRSLIKHQESHVQRTHQTAIRPCAEIKESVLHSR", "length": 891, "header": "tr|A0A8V1ADJ0-1|A0A8V1ADJ0_CHICK Isoform 1 of Zinc finger family member 767 OS=Gallus gallus OX=9031 GN=ZNF767 PE=4 SV=1 CANONICAL=A0A8V1ADJ0-1" }, "locus": { "chromosome": "2", "start_pos": 569935, "end_pos": 556452, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066060.1", "url": "https://www.ensembl.org/id/ENSGALT00010066060.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040326.1", "url": "https://www.ensembl.org/id/ENSGALP00010040326.1" } ] } }, { "isoform_ac": "A0A8V1AFK7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADJ0/entry#A0A8V1AFK7-1", "sequence": { "sequence": "MASALPGSCLCSSSLPQAPGEAVPSSTASISLWTVVAAVQAVEKSVEAHASRLLNLERRTVTTEKKYLDCEKTVVDFGNQLESKLTVLGTLIREYGQLQRRLEHMENLLKNRNFCILRLPPAPKGPEASESETACFAEQEWENLEEWQKELYRNMLRGNSESLNSLDYSVSRSDLSQLQRGEAPCSEVTSAQKEVPTEPSADFSIPEPSFTGTLKQNEEVCAEEQEATEGAEFTELSVVLTLQANQVDAASEKFSATTGLQPSSVQPVGVGASRIILRYKHGGAVA", "length": 286, "header": "tr|A0A8V1AFK7-1|A0A8V1AFK7_CHICK Computationally mapped isoform of Zinc finger family member 767 OS=Gallus gallus OX=9031 GN=ZNF767 PE=4 SV=1 CANONICAL=A0A8V1ADJ0-1" }, "locus": { "chromosome": "2", "start_pos": 563230, "end_pos": 556452, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066058.1", "url": "https://www.ensembl.org/id/ENSGALT00010066058.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040324.1", "url": "https://www.ensembl.org/id/ENSGALP00010040324.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-212436", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-212436", "resource": "Reactome", "description": "Generic Transcription Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1ME16-1", "protein_name": "Zinc finger protein 212", "gene_name": "ZNF212", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAELAPARHRRKHRSSPLTSSRPPPQATEKSSYLETTEISLWTVVAAIQAMEKKVESQAARLLTLEGRAGTAEKKLADCEKTAVELGNQLEGKWAVLGTLLQEYGLLQRRLENVENLLRNRNFWILRLPPGSNGEVPKVSRSLENDGVCFSEQEWENLEDWQKELYANVMKSNYETLVSLKVLGQPEGEVELGAEMPGDLEEEESRGVHPVEEVVVKQETLYTQDSSADLPGECSGFANEQALLSPEQAELWDGQGSSILLESGPADTRLQEPTDGGRDPGSGRTLGCPPKRKCHKQLQPGRECGQGLQLRRDSAGPCGCPECEAPHPQTPSEPEASPRPRPQLKPPARKAQSLQCDACARSFRCRVSLLTHQRCHLQEAARAGHPAQERFSPNSLVALPGHIPWRRSRGSLLCGYCGKSFSHPSDLVRHQRIHTGERPYSCPECEKSFVQKQHLLQHQKIHQRERGGPALQPARPSGLL", "length": 480 }, "evidence": [ { "id": "A0A8V1ADJ0", "url": "https://omabrowser.org/oma/group/A0A8V1ADJ0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3V6U6-1", "protein_name": "Zinc finger protein 212", "gene_name": "Zfp212", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAESTPARHRRKRRSTPLAPATPPSQTTEKSQYFQTTEISLWTVVAAIQAVEKKMESQAARLQSLEGRAGSAEKKLADFEKTAVEFSNQLEGKWAVLGTLLQEYGLLQRRLENVENLLRNKNFWVLRLPPGSKGETPKVSGPLENDGVCFSEQEWENLEDWQKELYRNVMESNYETLVSLKVLGQPEEEVELGAEMVGDLVEEGTHLADRAMVKQEMLYKQEGPSGLPSMFSSAAEPQACFGSEQAVFWNSPGDSALLESGPGDSNPESVESSRDPAPGRNLDCPRKQKSHRQVQLGQECGQGPKVKRDTSPYKCSECQISFRYKQQLTAHLQSHTSRESYSATEPEESLRPRPRLKPQAKRSKLHQCDVCHRSFSCKVSLVTHQRCHQQEGPSTSPQIQERFSPNSLVALPGHIPWRKSRSSLICGYCGKSFSHPSDLVRHQRIHTGERPYSCPECEKSFVQKQHLLQHQKIHQRERGGLASESARPNGLL", "length": 492 }, "evidence": [ { "id": "A0A8V1ADJ0", "url": "https://omabrowser.org/oma/group/A0A8V1ADJ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3X8R7-1", "protein_name": "Zinc finger protein 212", "gene_name": "Zfp212", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAESTPTRHRRKRRATPLAPATPPSQTTEKSPYFQTTEISLWTVVAAIQAVEKKMESQAARLQSLEGRAGSAEKKLADFEKTAVEFSNQLEGKWAVLGTLLQEYGLLQRRLENVENLLRNKNFWVLRLPPGSKGETPKVSGSLENDGVCFSEQEWENLEDWQKELYRNVMESNYETLVSLKVLGQPEEEVELGAEMVGDLVEEGTHLADRAMVKQEMLYKQEGPAGLPNMFSSAVEQQAFFGAEQAMFWNSPGDSALLESGPGDSNPESVETSRDPAPGRNLDCPRKQKSHRQVQLGQECGQGLKVKRDSSPYKCPECQISFRYKQQLTAHLQSHAGRESYSATEPEESLRPRPRLKPQAKRSKLHQCDVCHRSFSCKVSLVTHQRCHQQEGPSTSPQIQERFSPNSLVALPGHIPWRKSRSSLICGYCGKSFSHPSDLVRHQRIHTGERPYSCPECEKSFVQKQHLLQHQKIHQRERGGLASESARPNGLL", "length": 492 }, "evidence": [ { "id": "A0A8V1ADJ0", "url": "https://omabrowser.org/oma/group/A0A8V1ADJ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9UDV6-1", "protein_name": "Zinc finger protein 212", "gene_name": "ZNF212", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAESAPARHRRKRRSTPLTSSTLPSQATEKSSYFQTTEISLWTVVAAIQAVEKKMESQAARLQSLEGRTGTAEKKLADCEKMAVEFGNQLEGKWAVLGTLLQEYGLLQRRLENVENLLRNRNFWILRLPPGSKGEAPKVSRSLENDGVCFTEQEWENLEDWQKELYRNVMESNYETLVSLKVLGQTEGEAELGTEMLGDLEEEGPGGAHPAGGVMIKQELQYTQEGPADLPGEFSCIAEEQAFLSPEQTELWGGQGSSVLLETGPGDSTLEEPVGSRVPSSSRTVGCPKQKSHRQVQLDQECGQGLKLKKDTSRPYECSECEITFRYKQQLATHLRSHSGWGSCTPEEPEESLRPRPRLKPQTKKAKLHQCDVCLRSFSCKVSLVTHQRCHLQEGPSAGQHVQERFSPNSLVALPGHIPWRKSRSSLICGYCGKSFSHPSDLVRHQRIHTGERPYSCTECEKSFVQKQHLLQHQKIHQRERGGLALEPGRPNGLL", "length": 495 }, "evidence": [ { "id": "A0A8V1ADJ0", "url": "https://omabrowser.org/oma/group/A0A8V1ADJ0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADJ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADJ0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADJ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADJ0" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADJ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADJ0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADJ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADJ0" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADJ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADJ0" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADJ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADJ0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 297, "end_pos": 299, "annotation": "n_glycosylation_sequon" }, { "start_pos": 353, "end_pos": 355, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1ADJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADJ0" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 427, "end_pos": 454, "start_aa": "Tyr", "end_aa": "Pro", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1ADJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADJ0" }, { "id": "PS50805", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50805" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "KRAB", "eco_id": "ECO_0000259", "start_pos": 127, "end_pos": 233, "start_aa": "Glu", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 297, "end_pos": 299 }, { "start_pos": 353, "end_pos": 355 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AAX0-1", "uniprot_ac": "A0A8V1AAX0", "uniprot_id": "A0A8V1AAX0_CHICK", "mass": { "chemical_mass": 45690.0, "monoisotopic_mass": 45690.0 }, "refseq": {}, "gene_names": [ { "name": "FAM212B", "type": "recommended", "evidence": [ { "id": "A0A8V1AAX0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAX0" } ] } ], "protein_names": [ { "name": "PAK4-inhibitor INKA2", "type": "recommended", "evidence": [ { "id": "A0A8V1AAX0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAX0/entry#names_and_taxonomy" } ] }, { "name": "PAK4-inhibitor inka2", "type": "synonym", "evidence": [ { "id": "A0A8V1AAX0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAX0/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Inhibitor of the serine/threonine-protein kinase PAK4. Acts by binding PAK4 in a substrate-like manner, inhibiting the protein kinase activity.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A3C6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3C6#function" }, { "database": "UniProtKB", "id": "ARBA00045406", "url": "https://www.uniprot.org/uniprotkb/ARBA00045406#function" }, { "database": "UniProtKB", "id": "A0A8V1A8A1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8A1#function" }, { "database": "UniProtKB", "id": "A0A8V1AAW5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAW5#function" }, { "database": "UniProtKB", "id": "A0A8V1AAX0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAX0#function" }, { "database": "UniProtKB", "id": "A0A8V1AFQ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFQ3#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAX0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAX0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FAM212B", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAX0", "locus": {} } ], "crossref": [ { "id": "A0A8V1AAX0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AAX0", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR029267", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029267", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039201", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039201", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A3C6", "url": "https://www.orthodb.org/?gene=A0A8V1A3C6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A8A1", "url": "https://www.orthodb.org/?gene=A0A8V1A8A1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AAW5", "url": "https://www.orthodb.org/?gene=A0A8V1AAW5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AAX0", "url": "https://www.orthodb.org/?gene=A0A8V1AAX0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AFQ3", "url": "https://www.orthodb.org/?gene=A0A8V1AFQ3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR28615", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28615", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR28615:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28615:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15342", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15342", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1A3C6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3C6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A3C6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3C6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A8A1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8A1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A8A1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8A1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AAW5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAW5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AAW5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAW5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AAX0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAX0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AAX0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAX0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFQ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFQ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFQ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFQ3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGRWAAPHRPLLWAGHPPPESCGSPIPAPPGPSAGGGGAGPPRRAVPARSGLGLGPPRGAGSAGTPLPFSPFSSPPRCVQAERGAAHGGAALSPAMEHHLRRLKQELLSMKEVGDGLHQQMNCMMGALQELKLLQVQAALEQLEISGGRGPIPEQHQRCQGSTEGPEERPRSRAGAGGCSPSSLTCSVPQPALPHPTSLPESGHLGDIASSSSSSSSCGQDSSRSKGPSPAPARTERAHPRTTECSSQGMAGGWPVCDDSRDWTSSLMSQSRTRQPLVLGDNIFADLVGNWLDLPELDKKGEKSEASLSAGRSQELCRKFSLTANIFKKFLRSVRPDRDRLLKEKPCWLPPEDKQPEISKRPKKTNKLKGTFYFPLHGNIQNHHNKAERCPKVESHIEKPKMGAKKVHDTIDYTQSGFDINTAVWV", "length": 426, "header": "tr|A0A8V1AAX0-1|A0A8V1AAX0_CHICK Isoform 1 of PAK4-inhibitor INKA2 OS=Gallus gallus OX=9031 GN=FAM212B PE=3 SV=1 CANONICAL=A0A8V1AAX0-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A3C6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAX0/entry#A0A8V1A3C6-1", "sequence": { "sequence": "MVSGDLSWEQCSDPLSMKEVGDGLHQQMNCMMGALQELKLLQVQAALEQLEISGGRGPIPEQHQRCQGSTEGPEERPRSRAGAGGCSPSSLTCSVPQPALPHPTSLPESGHLGDIASSSSSSSSCGQDSSRSKGPSPAPARTERAHPRTTECSSQGMAGGWPVCDDSRDWTSSLMSQSRTRQPLVLGDNIFADLVGNWLDLPELDKKGEKSEASLSAGRSQELCRKFSLTANIFKKFLRSVRPDRDRLLKEKPCWLPPEDKQPEISKRPKKTNKLKGTFYFPLHGNIQNHHNKAERCPKVESHIEKPKMGAKKVHDTIDYTQSGFDINTAVWV", "length": 333, "header": "tr|A0A8V1A3C6-1|A0A8V1AAX0_CHICK Computationally mapped isoform of PAK4-inhibitor INKA2 OS=Gallus gallus OX=9031 GN=FAM212B PE=3 SV=1 CANONICAL=A0A8V1AAX0-1" }, "locus": { "chromosome": "26", "start_pos": 3316470, "end_pos": 3307544, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066117.1", "url": "https://www.ensembl.org/id/ENSGALT00010066117.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040383.1", "url": "https://www.ensembl.org/id/ENSGALP00010040383.1" } ] } }, { "isoform_ac": "A0A8V1A8A1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAX0/entry#A0A8V1A8A1-1", "sequence": { "sequence": "MVTSLPELAGACLRAGALLLSMKEVGDGLHQQMNCMMGALQELKLLQVQAALEQLEISGGRGPIPEQHQRCQGSTEGPEERPRSRAGAGGCSPSSLTCSVPQPALPHPTSLPESGHLGDIASSSSSSSSCGQDSSRSKGPSPAPARTERAHPRTTECSSQGMAGGWPVCDDSRDWTSSLMSQSRTRQPLVLGDNIFADLVGNWLDLPELDKKGEKSEASLSAGRSQELCRKFSLTANIFKKFLRSVRPDRDRLLKEKPCWLPPEDKQPEISKRPKKTNKLKGTFYFPLHGNIQNHHNKAERCPKVESHIEKPKMGAKKVHDTIDYTQSGFDINTAVWV", "length": 338, "header": "tr|A0A8V1A8A1-1|A0A8V1AAX0_CHICK Computationally mapped isoform of PAK4-inhibitor INKA2 OS=Gallus gallus OX=9031 GN=FAM212B PE=3 SV=1 CANONICAL=A0A8V1AAX0-1" }, "locus": { "chromosome": "26", "start_pos": 3316580, "end_pos": 3307544, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066119.1", "url": "https://www.ensembl.org/id/ENSGALT00010066119.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040385.1", "url": "https://www.ensembl.org/id/ENSGALP00010040385.1" } ] } }, { "isoform_ac": "A0A8V1AAW5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAX0/entry#A0A8V1AAW5-1", "sequence": { "sequence": "MPASSDLLKLSMKEVGDGLHQQMNCMMGALQELKLLQVQAALEQLEISGGRGPIPEQHQRCQGSTEGPEERPRSRAGAGGCSPSSLTCSVPQPALPHPTSLPESGHLGDIASSSSSSSSCGQDSSRSKGPSPAPARTERAHPRTTECSSQGMAGGWPVCDDSRDWTSSLMSQSRTRQPLVLGDNIFADLVGNWLDLPELDKKGEKSEASLSAGRSQELCRKFSLTANIFKKFLRSVRPDRDRLLKEKPCWLPPEDKQPEISKRPKKTNKLKGTFYFPLHGNIQNHHNKAERCPKVESHIEKPKMGAKKVHDTIDYTQSGFDINTAVWV", "length": 328, "header": "tr|A0A8V1AAW5-1|A0A8V1AAW5_CHICK Computationally mapped isoform of PAK4-inhibitor INKA2 OS=Gallus gallus OX=9031 GN=FAM212B PE=3 SV=1 CANONICAL=A0A8V1AAX0-1" }, "locus": { "chromosome": "26", "start_pos": 3315949, "end_pos": 3307544, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066116.1", "url": "https://www.ensembl.org/id/ENSGALT00010066116.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040382.1", "url": "https://www.ensembl.org/id/ENSGALP00010040382.1" } ] } }, { "isoform_ac": "A0A8V1AAX0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAX0/entry#A0A8V1AAX0-1", "sequence": { "sequence": "MGRWAAPHRPLLWAGHPPPESCGSPIPAPPGPSAGGGGAGPPRRAVPARSGLGLGPPRGAGSAGTPLPFSPFSSPPRCVQAERGAAHGGAALSPAMEHHLRRLKQELLSMKEVGDGLHQQMNCMMGALQELKLLQVQAALEQLEISGGRGPIPEQHQRCQGSTEGPEERPRSRAGAGGCSPSSLTCSVPQPALPHPTSLPESGHLGDIASSSSSSSSCGQDSSRSKGPSPAPARTERAHPRTTECSSQGMAGGWPVCDDSRDWTSSLMSQSRTRQPLVLGDNIFADLVGNWLDLPELDKKGEKSEASLSAGRSQELCRKFSLTANIFKKFLRSVRPDRDRLLKEKPCWLPPEDKQPEISKRPKKTNKLKGTFYFPLHGNIQNHHNKAERCPKVESHIEKPKMGAKKVHDTIDYTQSGFDINTAVWV", "length": 426, "header": "tr|A0A8V1AAX0-1|A0A8V1AAX0_CHICK Isoform 1 of PAK4-inhibitor INKA2 OS=Gallus gallus OX=9031 GN=FAM212B PE=3 SV=1 CANONICAL=A0A8V1AAX0-1" }, "locus": { "chromosome": "26", "start_pos": 3317204, "end_pos": 3307544, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066121.1", "url": "https://www.ensembl.org/id/ENSGALT00010066121.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040387.1", "url": "https://www.ensembl.org/id/ENSGALP00010040387.1" } ] } }, { "isoform_ac": "A0A8V1AFQ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAX0/entry#A0A8V1AFQ3-1", "sequence": { "sequence": "MGTPNQLGTGKDAGVWMSYLRAVGWELSMKEVGDGLHQQMNCMMGALQELKLLQVQAALEQLEISGGRGPIPEQHQRCQGSTEGPEERPRSRAGAGGCSPSSLTCSVPQPALPHPTSLPESGHLGDIASSSSSSSSCGQDSSRSKGPSPAPARTERAHPRTTECSSQGMAGGWPVCDDSRDWTSSLMSQSRTRQPLVLGDNIFADLVGNWLDLPELDKKGEKSEASLSAGRSQELCRKFSLTANIFKKFLRSVRPDRDRLLKEKPCWLPPEDKQPEISKRPKKTNKLKGTFYFPLHGNIQNHHNKAERCPKVESHIEKPKMGAKKVHDTIDYTQSGFDINTAVWV", "length": 345, "header": "tr|A0A8V1AFQ3-1|A0A8V1AFQ3_CHICK Computationally mapped isoform of PAK4-inhibitor INKA2 OS=Gallus gallus OX=9031 GN=FAM212B PE=3 SV=1 CANONICAL=A0A8V1AAX0-1" }, "locus": { "chromosome": "26", "start_pos": 3314424, "end_pos": 3307544, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066113.1", "url": "https://www.ensembl.org/id/ENSGALT00010066113.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040379.1", "url": "https://www.ensembl.org/id/ENSGALP00010040379.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAX0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAX0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein serine/threonine kinase inhibitor activity", "id": "GO:0030291", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030291", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAX0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAX0" } ], "pmid": "" }, { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAX0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAX0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AAX0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAX0" }, { "id": "PF15342", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15342" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "FAM212", "eco_id": "ECO_0000259", "start_pos": 238, "end_pos": 297, "start_aa": "Ala", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": 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"https://alphafold.ebi.ac.uk/entry/A0A8V1ABB3", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR011701", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011701", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020846", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020846", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036259", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036259", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050327", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050327", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A3R5", "url": "https://www.orthodb.org/?gene=A0A8V1A3R5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ABB3", "url": "https://www.orthodb.org/?gene=A0A8V1ABB3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AE32", "url": "https://www.orthodb.org/?gene=A0A8V1AE32", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AG37", "url": "https://www.orthodb.org/?gene=A0A8V1AG37", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11360", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11360", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11360:SF14", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11360:SF14", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07690", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07690", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1A3R5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3R5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A3R5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3R5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ABB3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABB3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ABB3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABB3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AE32", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE32", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AE32-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE32-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AG37", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG37", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AG37-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG37-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQQHSGERKEGKPEPPAVMGDGSQGTDRGWAWAAVLHFFLVNVFVMGMLKTFGIFFVAFQEEVGGSSEQVSWIGSIMSSLRFLGAPLVAVVCRRIGERPTSILGAGLVSGGCLLSTQATSVPFLCVSMGLLLGMGFCCLYQAAAVMTAKRCRTRLAFSNAVARSGMGLTFLTAPFTQLLIDTYGWQGALLIFSGIMLNLVPSSMLLRPIRTQLPPCPPASNEDRSSVPKGEAGALAGHLEEATNGAARPCSARDPPSTEPPAEPCSSDAVTTAAAGKASTDSRSPETTNEATRSCRSPPVPKEEKPQPLIDFSPLKDPIFCIFTWSFLFSHLAYFVPIFHLVARARTLGISSMDASYLISVAGITETGSQLLSGWIADQNWTKKYHYHAAYLVLCGVTNLLCPLATTFPLLMAYAVAFAIFCGGFLALVLPVLVDLVGVQKLHSYLGFASFFAGIAAVGGPPLAGCCTGSAHKAARLGGCGDCSADVAKPDTCKASHYPAGPHICCSSHFWPSWLKRKRKNVGD", "length": 524, "header": "tr|A0A8V1ABB3-1|A0A8V1ABB3_CHICK Isoform 1 of Solute carrier family 16 member 4 OS=Gallus gallus OX=9031 GN=SLC16A4 PE=4 SV=1 CANONICAL=A0A8V1ABB3-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A3R5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABB3/entry#A0A8V1A3R5-1", "sequence": { "sequence": "MQQHSGERKEGKPEPPAVMGDGSQGTDRGWAWAAVLHFFLVNVFVMGMLKTFGIFFVAFQEEVGGSSEQVSWIGSIMSSLRFLGAPLVAVVCRRIGERPTSILGAGLVSGGCLLSTQATSVPFLCVSMGLLLGMGFCCLYQAAAVMTAKRCRTRLAFSNAVARSGMGLTFLTAPFTQLLIDTYGWQGALLIFSGIMLNLVPSSMLLRPIRTQLPPCPPASNEDRSSVPKGEAGALAGHLEEATNGAARPCSARDPPSTEPPAEPCSSDAVTTAAAGKASTDSRSPETTNEATRSCRSPPVPKEEKPQPLIDFSPLKDPIFCIFTWSFLFSHLAYFVPIFHLVARARTLGISSMDASYLISVAGITETGSQLLSGWIADQNWTKKYHYHAAYLVLCGVTNLLCPLATTFPLLMAYAVAFAIFCGGFLALVLPVLVDLVGVQKLHSYLGFASFFAGIAAVGGPPLAGIHGWLFCPRR", "length": 475, "header": "tr|A0A8V1A3R5-1|A0A8V1ABB3_CHICK Computationally mapped isoform of Solute carrier family 16 member 4 OS=Gallus gallus OX=9031 GN=SLC16A4 PE=4 SV=1 CANONICAL=A0A8V1ABB3-1" }, "locus": { "chromosome": "26", "start_pos": 1458665, "end_pos": 1453311, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066259.1", "url": "https://www.ensembl.org/id/ENSGALT00010066259.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040525.1", "url": "https://www.ensembl.org/id/ENSGALP00010040525.1" } ] } }, { "isoform_ac": "A0A8V1ABB3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABB3/entry#A0A8V1ABB3-1", "sequence": { "sequence": "MQQHSGERKEGKPEPPAVMGDGSQGTDRGWAWAAVLHFFLVNVFVMGMLKTFGIFFVAFQEEVGGSSEQVSWIGSIMSSLRFLGAPLVAVVCRRIGERPTSILGAGLVSGGCLLSTQATSVPFLCVSMGLLLGMGFCCLYQAAAVMTAKRCRTRLAFSNAVARSGMGLTFLTAPFTQLLIDTYGWQGALLIFSGIMLNLVPSSMLLRPIRTQLPPCPPASNEDRSSVPKGEAGALAGHLEEATNGAARPCSARDPPSTEPPAEPCSSDAVTTAAAGKASTDSRSPETTNEATRSCRSPPVPKEEKPQPLIDFSPLKDPIFCIFTWSFLFSHLAYFVPIFHLVARARTLGISSMDASYLISVAGITETGSQLLSGWIADQNWTKKYHYHAAYLVLCGVTNLLCPLATTFPLLMAYAVAFAIFCGGFLALVLPVLVDLVGVQKLHSYLGFASFFAGIAAVGGPPLAGCCTGSAHKAARLGGCGDCSADVAKPDTCKASHYPAGPHICCSSHFWPSWLKRKRKNVGD", "length": 524, "header": "tr|A0A8V1ABB3-1|A0A8V1ABB3_CHICK Isoform 1 of Solute carrier family 16 member 4 OS=Gallus gallus OX=9031 GN=SLC16A4 PE=4 SV=1 CANONICAL=A0A8V1ABB3-1" }, "locus": { "chromosome": "26", "start_pos": 1458665, "end_pos": 1450351, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066263.1", "url": "https://www.ensembl.org/id/ENSGALT00010066263.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040529.1", "url": "https://www.ensembl.org/id/ENSGALP00010040529.1" } ] } }, { "isoform_ac": "A0A8V1AE32-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABB3/entry#A0A8V1AE32-1", "sequence": { "sequence": "MQQHSGERKEGKPEPPAVMGDGSQGTDRGWAWAAVLHFFLVNVFVMGMLKTFGIFFVAFQEEVGGSSEQVSWIGSIMSSLRFLGAPLVAVVCRRIGERPTSILGAGLVSGGCLLSTQATSVPFLCVSMGLLLGMGFCCLYQAAAVMTAKRCRTRLAFSNAVARSGMGLTFLTAPFTQLLIDTYGWQGALLIFSGIMLNLVPSSMLLRPIRTQLPPCPPASNEDRSSVPKGEAGALAGHLEEATNGAARPCSARDPPSTEPPAEPCSSDAVTTAAAGKASTDSRSPETTNEATRSCRSPPVPKEEKPQPLIDFSPLKDPIFCIFTWSFLFSHLAYFVPIFHLVARARTLGISSMDASYLISVAGITETGSQLLSGWIADQNWTKKYHYHAAYLVLCGVTNLLCPLATTFPLLMAYAVAFAIFCGGFLALVLPVLVDLVGVQKLHSYLGFASFFAGIAAVGGPPLAGRQSLAEYSTQTSKSTNTTQGHEALNEVTFHV", "length": 496, "header": "tr|A0A8V1AE32-1|A0A8V1AE32_CHICK Computationally mapped isoform of Solute carrier family 16 member 4 OS=Gallus gallus OX=9031 GN=SLC16A4 PE=4 SV=1 CANONICAL=A0A8V1ABB3-1" }, "locus": { "chromosome": "26", "start_pos": 1458665, "end_pos": 1443346, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066267.1", "url": "https://www.ensembl.org/id/ENSGALT00010066267.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040533.1", "url": "https://www.ensembl.org/id/ENSGALP00010040533.1" } ] } }, { "isoform_ac": "A0A8V1AG37-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABB3/entry#A0A8V1AG37-1", "sequence": { "sequence": "MTRRFLFAFCCFGEGLPACSSTAVNVFVMGMLKTFGIFFVAFQEEVGGSSEQVSWIGSIMSSLRFLGAPLVAVVCRRIGERPTSILGAGLVSGGCLLSTQATSVPFLCVSMGLLLGMGFCCLYQAAAVMTAKRCRTRLAFSNAVARSGMGLTFLTAPFTQLLIDTYGWQGALLIFSGIMLNLVPSSMLLRPIRTQLPPCPPASNEDRSSVPKGEAGALAGHLEEATNGAARPCSARDPPSTEPPAEPCSSDAVTTAAAGKASTDSRSPETTNEATRSCRSPPVPKEEKPQPLIDFSPLKDPIFCIFTWSFLFSHLAYFVPIFHLVARARTLGISSMDASYLISVAGITETGSQLLSGWIADQNWTKKYHYHAAYLVLCGVTNLLCPLATTFPLLMAYAVAFAIFCGGFLALVLPVLVDLVGVQKLHSYLGFASFFAGIAAVGGPPLAGWLYDYTQTYACSFLFAGACALLSPVSFFLEPLAQRWKLQKANVPMQSEAILQGSSGRSSFGCSHSQTSASTDLQR", "length": 523, "header": "tr|A0A8V1AG37-1|A0A8V1ABB3_CHICK Computationally mapped isoform of Solute carrier family 16 member 4 OS=Gallus gallus OX=9031 GN=SLC16A4 PE=4 SV=1 CANONICAL=A0A8V1ABB3-1" }, "locus": { "chromosome": "26", "start_pos": 1458718, "end_pos": 1449850, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066265.1", "url": "https://www.ensembl.org/id/ENSGALT00010066265.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040531.1", "url": "https://www.ensembl.org/id/ENSGALP00010040531.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABB3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABB3" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABB3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABB3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "transmembrane transporter activity", "id": "GO:0022857", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022857", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABB3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABB3" } ], "pmid": "" }, { "name": "monocarboxylic acid transmembrane transporter activity", "id": "GO:0008028", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008028", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABB3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABB3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "carboxylic acid transmembrane transport", "id": "GO:1905039", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905039", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABB3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABB3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 380, "end_pos": 382, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 380, "end_pos": 382 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AE27-1", "uniprot_ac": "A0A8V1AE27", "uniprot_id": "A0A8V1AE27_CHICK", "mass": { "chemical_mass": 37440.0, "monoisotopic_mass": 37440.0 }, "refseq": {}, "gene_names": [ { "name": "HDGF", "type": "recommended", "evidence": [ { "id": "A0A8V1AE27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE27" } ] } ], "protein_names": [ { "name": "Heparin binding growth factor", "type": "synonym", "evidence": [ { "id": "A0A8V1AE27", "database": "UniProtKB", "url": 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"https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20148", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000313", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000313", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047363", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047363", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A3S0", "url": "https://www.orthodb.org/?gene=A0A8V1A3S0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ABA7", "url": "https://www.orthodb.org/?gene=A0A8V1ABA7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AE27", "url": "https://www.orthodb.org/?gene=A0A8V1AE27", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AG33", "url": "https://www.orthodb.org/?gene=A0A8V1AG33", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12550", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12550", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12550:SF41", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12550:SF41", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00855", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00855", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1A3S0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3S0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A3S0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3S0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ABA7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABA7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ABA7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABA7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AE27", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE27", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AE27-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE27-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AG33", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG33", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AG33-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG33-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRGWGGKGAIEFKPKQPHGAGAAVPRRSQIGPGPRPPPPPPPAPRWGPPAPPSARCSLSPSLPPSLSLTPPPPPPFFLCVCVVFFFSSRRVPAPKLHAGPPPRPAAATMSRSHRQKEYKCGDLVFAKMKGYPHWPARIDEMPEAAVKSSSNKYQVFFFGTHETAFLGPKDLFPYEECKEKFGKPNKRKGFSEGLWEIEHNPTVKASGYQPTQKKTCPEDAEPEQEPEGDGEKKGNAEGSSDEEGKLVIDEQSKEKNEKAGIKRKAEDVLEDSPKRTKEMEGQEAEKKTDNEEAPKEEPKPNPAEEEKEKNSDAASVPDANEAKQEGKDKAEEVRDHKESL", "length": 340, "header": "tr|A0A8V1AE27-1|A0A8V1AE27_CHICK Isoform 1 of Heparin binding growth factor OS=Gallus gallus OX=9031 GN=HDGF PE=1 SV=1 CANONICAL=A0A8V1AE27-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A3S0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE27/entry#A0A8V1A3S0-1", "sequence": { "sequence": "MAAGIGPEAFAAVREAVMGLGAATMSRSHRQKEYKCGDLVFAKMKGYPHWPARIDEMPEAAVKSSSNKYQVFFFGTHETAFLGPKDLFPYEECKEKFGKPNKRKGFSEGLWEIEHNPTVKASGYQPTQKKTCPEDAEPEQEPEGDGEKKGNAEGSSDEEGKLVIDEQSKEKNEKAGIKRKAEDVLEDSPKRTKEMEGQEAEKKTDNEEAPKEEPKPNPAEEEKEKNSDAASVPDANEAKQEGKDKAEEVRDHKESL", "length": 256, "header": "tr|A0A8V1A3S0-1|A0A8V1AE27_CHICK Computationally mapped isoform of Heparin binding growth factor OS=Gallus gallus OX=9031 GN=HDGF PE=1 SV=1 CANONICAL=A0A8V1AE27-1" }, "locus": { "chromosome": "25", "start_pos": 1049050, "end_pos": 1042992, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066264.1", "url": "https://www.ensembl.org/id/ENSGALT00010066264.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040530.1", "url": "https://www.ensembl.org/id/ENSGALP00010040530.1" } ] } }, { "isoform_ac": "A0A8V1ABA7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE27/entry#A0A8V1ABA7-1", "sequence": { "sequence": "MQLRIRLRCPGWIQVYWGACPAQGCHNPCVICWFCPPCCWLIDEMPEAAVKSSSNKYQVFFFGTHETAFLGPKDLFPYEECKEKFGKPNKRKGFSEGLWEIEHNPTVKASGYQPTQKKTCPEDAEPEQEPEGDGEKKGNAEGSSDEEGKLVIDEQSKEKNEKAGIKRKAEDVLEDSPKRTKEMEGQEAEKKTDNEEAPKEEPKPNPAEEEKEKNSDAASVPDANEAKQEGKDKAEEVRDHKESL", "length": 244, "header": "tr|A0A8V1ABA7-1|A0A8V1ABA7_CHICK Computationally mapped isoform of Heparin binding growth factor OS=Gallus gallus OX=9031 GN=HDGF PE=1 SV=1 CANONICAL=A0A8V1AE27-1" }, "locus": { "chromosome": "25", "start_pos": 1044298, "end_pos": 1042992, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066258.1", "url": "https://www.ensembl.org/id/ENSGALT00010066258.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040524.1", "url": "https://www.ensembl.org/id/ENSGALP00010040524.1" } ] } }, { "isoform_ac": "A0A8V1AE27-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE27/entry#A0A8V1AE27-1", "sequence": { "sequence": "MRGWGGKGAIEFKPKQPHGAGAAVPRRSQIGPGPRPPPPPPPAPRWGPPAPPSARCSLSPSLPPSLSLTPPPPPPFFLCVCVVFFFSSRRVPAPKLHAGPPPRPAAATMSRSHRQKEYKCGDLVFAKMKGYPHWPARIDEMPEAAVKSSSNKYQVFFFGTHETAFLGPKDLFPYEECKEKFGKPNKRKGFSEGLWEIEHNPTVKASGYQPTQKKTCPEDAEPEQEPEGDGEKKGNAEGSSDEEGKLVIDEQSKEKNEKAGIKRKAEDVLEDSPKRTKEMEGQEAEKKTDNEEAPKEEPKPNPAEEEKEKNSDAASVPDANEAKQEGKDKAEEVRDHKESL", "length": 340, "header": "tr|A0A8V1AE27-1|A0A8V1AE27_CHICK Isoform 1 of Heparin binding growth factor OS=Gallus gallus OX=9031 GN=HDGF PE=1 SV=1 CANONICAL=A0A8V1AE27-1" }, "locus": { "chromosome": "25", "start_pos": 1048397, "end_pos": 1042992, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066262.1", "url": "https://www.ensembl.org/id/ENSGALT00010066262.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040528.1", "url": "https://www.ensembl.org/id/ENSGALP00010040528.1" } ] } }, { "isoform_ac": "A0A8V1AG33-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE27/entry#A0A8V1AG33-1", "sequence": { "sequence": "MSRSHRQKEYKCGDLVFAKMKGYPHWPARIDEMPEAAVKSSSNKYQVFFFGTHETAFLGPKDLFPYEECKEKFGKPNKRKGFSEGLWEIEHNPTVKASGYQPTQKKTCPEDAEPEQEPEGDGEKKGNAEGSSDEEGKLVIDEQSKEKNEKAGIKRKAEDVLEDSPKRTKEMEGQEAEKKTDNEEAPKEEPKPNPAEEEKEKNSDAASVPDANEAKQEGKDKAEEVRDHKERVVGPFLPLWVILRTWCQKI", "length": 250, "header": "tr|A0A8V1AG33-1|A0A8V1AE27_CHICK Computationally mapped isoform of Heparin binding growth factor OS=Gallus gallus OX=9031 GN=HDGF PE=1 SV=1 CANONICAL=A0A8V1AE27-1" }, "locus": { "chromosome": "25", "start_pos": 1048073, "end_pos": 1042583, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066260.1", "url": "https://www.ensembl.org/id/ENSGALT00010066260.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040526.1", "url": "https://www.ensembl.org/id/ENSGALP00010040526.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AE27", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE27" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "chromatin remodeling", "id": "GO:0006338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006338", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AE27", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE27" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AE27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE27" }, { "id": "PS50812", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50812" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PWWP", "eco_id": "ECO_0000259", "start_pos": 120, "end_pos": 177, "start_aa": "Cys", "end_aa": "Cys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AEC4-1", "uniprot_ac": "A0A8V1AEC4", "uniprot_id": "A0A8V1AEC4_CHICK", "mass": { "chemical_mass": 44115.0, "monoisotopic_mass": 44115.0 }, "refseq": {}, "gene_names": [ { "name": "PRSS57", "type": "recommended", "evidence": [ { "id": "A0A8V1AEC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEC4" } ] } ], "protein_names": [ { "name": "Serine protease 57", "type": "synonym", "evidence": [ { "id": "A0A8V1AEC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEC4/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEC4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEC4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PRSS57", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEC4", "locus": { "chromosome": "28", "start_pos": 3182764, "end_pos": 3186587, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027371", "url": "https://www.ensembl.org/id/ENSGALG00010027371" } ] } } ], "crossref": [ { "id": "A0A8V1AEC4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AEC4", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00190", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00190", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001254", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001254", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001314", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001314", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009003", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009003", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018114", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018114", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A422", "url": "https://www.orthodb.org/?gene=A0A8V1A422", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ABM8", "url": "https://www.orthodb.org/?gene=A0A8V1ABM8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AEC4", "url": "https://www.orthodb.org/?gene=A0A8V1AEC4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24271", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24271", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24271:SF55", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24271:SF55", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00089", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00089", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1A422", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A422", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A422-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A422-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ABM8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABM8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ABM8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABM8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AEC4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEC4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AEC4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEC4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRAAGHGLGSRSAFTLPSFIHSLPSRQPLLRSRGSCQAVPQAKLPPQLRDSKTEPPITPQRCISPSKMIAQGSNTERRKRGGTRRCPYSSCAHSTALRGYLTHPPSSGGPTGGGGGPRCTSMLAALLILSLGGSALGPAGAHSSWVIGGKAAVPHSRPFIASIQMDGQHFCGGFLVWPRREPSVRVVLGAHSLEQPEESQQVFGVEESIAHPLYNPRTVDNDIRMLRLNHTATLNAFVKRIRLPRPRIDLKPGTLCSVVGWGDISNYGERPIQLMEANTTIVKRSLCRTLWKGRVSGNMLCGASRNATLQGVCAGDSGGPLVFKGKVYGVVSFSGERCGDRRYPDIYTRISNYIDWVHHVVLSHRQPPGQRKDKPGPEKAEGDQGAAGWGRPGFPRPPPAPRGLMFNGN", "length": 409, "header": "tr|A0A8V1AEC4-1|A0A8V1AEC4_CHICK Isoform 1 of Serine protease 57 OS=Gallus gallus OX=9031 GN=PRSS57 PE=1 SV=1 CANONICAL=A0A8V1AEC4-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A422-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEC4/entry#A0A8V1A422-1", "sequence": { "sequence": "MRVAAPAPSRVLRHRVQREGSAGSQPPTLPQLHAAAATTGAHSSWVIGGKAAVPHSRPFIASIQMDGQHFCGGFLVWPRWVMTAAHCPVPRREPSVRVVLGAHSLEQPEESQQVFGVEESIAHPLYNPRTVDNDIRMLRLNHTATLNAFVKRIRLPRPRIDLKPGTLCSVVGWGDISNYGERPIQLMEANTTIVKRSLCRTLWKGRVSGNMLCGASRNATLQGVCAGDSGGPLVFKGKVYGVVSFSGERCGDRRYPDIYTRISNYIDWVHHVVLSHRQPPGQRKDKPGPEKAEGDQGAAGWGRPGFPRPPPAPRGLMFNGN", "length": 321, "header": "tr|A0A8V1A422-1|A0A8V1AEC4_CHICK Computationally mapped isoform of Serine protease 57 OS=Gallus gallus OX=9031 GN=PRSS57 PE=1 SV=1 CANONICAL=A0A8V1AEC4-1" }, "locus": { "chromosome": "28", "start_pos": 3186388, "end_pos": 3182935, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066365.1", "url": "https://www.ensembl.org/id/ENSGALT00010066365.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040631.1", "url": "https://www.ensembl.org/id/ENSGALP00010040631.1" } ] } }, { "isoform_ac": "A0A8V1ABM8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEC4/entry#A0A8V1ABM8-1", "sequence": { "sequence": "MIAQGSNTERRKRGGTRRCPYSSCAHSTALRGYLTHPPSSGGPTGGGGGPRCTSMLAALLILSLGGSALGPAGAHSSWVIGGKAAVPHSRPFIASIQMDGQHFCGGFLVWPRWVMTAAHCPVPRREPSVRVVLGAHSLEQPEESQQVFGVEESIAHPLYNPRTVDNDIRMLRLNHTATLNAFVKRIRLPRPRIDLKPGTLCSVVGWGDISNYGERPIQLMEANTTIVKRSLCRTLWKGRVSGNMLCGASRNATLQGVCAGDSGGPLVFKGKVYGVVSFSGERCGDRRYPDIYTRISNYIDWVHHVVLSHRQPPGQRKDKPGPEKAEGDQGAAGWGRPGFPRPPPAPRGLMFNGN", "length": 354, "header": "tr|A0A8V1ABM8-1|A0A8V1ABM8_CHICK Computationally mapped isoform of Serine protease 57 OS=Gallus gallus OX=9031 GN=PRSS57 PE=1 SV=1 CANONICAL=A0A8V1AEC4-1" }, "locus": { "chromosome": "28", "start_pos": 3184634, "end_pos": 3182935, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066364.1", "url": "https://www.ensembl.org/id/ENSGALT00010066364.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040630.1", "url": "https://www.ensembl.org/id/ENSGALP00010040630.1" } ] } }, { "isoform_ac": "A0A8V1AEC4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEC4/entry#A0A8V1AEC4-1", "sequence": { "sequence": "MRAAGHGLGSRSAFTLPSFIHSLPSRQPLLRSRGSCQAVPQAKLPPQLRDSKTEPPITPQRCISPSKMIAQGSNTERRKRGGTRRCPYSSCAHSTALRGYLTHPPSSGGPTGGGGGPRCTSMLAALLILSLGGSALGPAGAHSSWVIGGKAAVPHSRPFIASIQMDGQHFCGGFLVWPRREPSVRVVLGAHSLEQPEESQQVFGVEESIAHPLYNPRTVDNDIRMLRLNHTATLNAFVKRIRLPRPRIDLKPGTLCSVVGWGDISNYGERPIQLMEANTTIVKRSLCRTLWKGRVSGNMLCGASRNATLQGVCAGDSGGPLVFKGKVYGVVSFSGERCGDRRYPDIYTRISNYIDWVHHVVLSHRQPPGQRKDKPGPEKAEGDQGAAGWGRPGFPRPPPAPRGLMFNGN", "length": 409, "header": "tr|A0A8V1AEC4-1|A0A8V1AEC4_CHICK Isoform 1 of Serine protease 57 OS=Gallus gallus OX=9031 GN=PRSS57 PE=1 SV=1 CANONICAL=A0A8V1AEC4-1" }, "locus": { "chromosome": "28", "start_pos": 3184835, "end_pos": 3182935, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066363.1", "url": "https://www.ensembl.org/id/ENSGALT00010066363.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040629.1", "url": "https://www.ensembl.org/id/ENSGALP00010040629.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 111, "start_aa": "Thr", "end_pos": 111, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr111", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "serine-type endopeptidase activity", "id": "GO:0004252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004252", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEC4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEC4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEC4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEC4" } ], "pmid": "" }, { "name": "protein maturation", "id": "GO:0051604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051604", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEC4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEC4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEC4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEC4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 229, "end_pos": 231, "annotation": "n_glycosylation_sequon" }, { "start_pos": 278, "end_pos": 280, "annotation": "n_glycosylation_sequon" }, { "start_pos": 306, "end_pos": 308, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AEC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEC4" }, { "id": "PS50240", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50240" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Peptidase S1", "eco_id": "ECO_0000259", "start_pos": 146, "end_pos": 362, "start_aa": "Val", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 111 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 229, "end_pos": 231 }, { "start_pos": 278, "end_pos": 280 }, { "start_pos": 306, "end_pos": 308 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1ABS4-1", "uniprot_ac": "A0A8V1ABS4", "uniprot_id": "A0A8V1ABS4_CHICK", "mass": { "chemical_mass": 98946.0, "monoisotopic_mass": 98946.0 }, "refseq": { "ac": "XP_015142269", "name": "serine/threonine-protein phosphatase 6 regulatory subunit 3 isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015142269" }, "gene_names": [ { "name": "PPP6R3", "type": "recommended", "evidence": [ { "id": "A0A8V1ABS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABS4" } ] }, { "name": "PPP6R3", "type": "synonym", "evidence": [ { "id": "XP_015142269", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015142269" } ] }, { "name": "SAPS3", "type": "synonym", "evidence": [ { "id": "XP_015142269", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015142269" } ] } ], "protein_names": [ { "name": "Protein phosphatase 6 regulatory subunit 3", "type": "synonym", "evidence": [ { "id": "A0A8V1ABS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABS4/entry#names_and_taxonomy" } ] }, { "name": "serine/threonine-protein phosphatase 6 regulatory subunit 3 isoform X3", "type": "synonym", "evidence": [ { "id": "XP_015142269", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015142269" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052536.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015142269", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015142269" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABS4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABS4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PPP6R3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABS4", "locus": { "chromosome": "5", "start_pos": 16121938, "end_pos": 16070261, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010025835", "url": "https://www.ensembl.org/id/ENSGALG00010025835" } ] } } ], "crossref": [ { "id": "A0A8V1ABS4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1ABS4", "database": "AlphaFoldDB", "categories": [] }, { "id": "423116", "url": "https://www.ncbi.nlm.nih.gov/gene/423116", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007587", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007587", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A4C7", "url": "https://www.orthodb.org/?gene=A0A8V1A4C7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A6Q9", "url": "https://www.orthodb.org/?gene=A0A8V1A6Q9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A9D3", "url": "https://www.orthodb.org/?gene=A0A8V1A9D3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ABS4", "url": "https://www.orthodb.org/?gene=A0A8V1ABS4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12634", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12634", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12634:SF12", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12634:SF12", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04499", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04499", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-171319", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-171319", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-204005", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-204005", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015142269", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015142269", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1A4C7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4C7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A4C7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4C7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A6Q9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6Q9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A6Q9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6Q9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A9D3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9D3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A9D3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9D3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ABS4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABS4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ABS4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABS4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFAVTSMFWKFDLHSSSHIDTLLEREDVTLKELMDEEDVLQECKAQNRKLIEFLLKSECLEDLVSFIIEEPPQDMDEKIRYKYPNISCELLTSDVSQINDRLGEEESLLMKLYSFLLNESPLNPLLASFFSKVLSILISRKPEQIVDFLKKKHDFVDLVIKHIGTSAIMDLLLRLLTCIEPPQPRQEVLNWLNEERIIQRLVEIVHPSQDEDRHSNASQSLCEIIRLSRDQMLQVQNSSEPDPLLASLEKREIIEQLLSNIFHKEKNESAIVSAIQILLTLLETRRQTFEGHIEICPPGMSNSTYSVNKSVLEAIKARLSSFHELLLEPPKKSVMKTTWGVLDPPVGNTRLNVIRLISSLLQTNTSSVNQELIELNSIGVILDMFFKYTWNNFLHTQVEICIALILASPLESTENGTITDQDSTGDNLLLKHLFLKCQLIERILEAWEMNEKKQAEGGRRHGYMGHLTRIANCIVHSTDKGPNSTLVQQLIKELPEEVRERWETFCTSSLGETNKRNTVDLVTTCHIHSSSDDEIDFKETGFSQDSSLQQAFSDYQMQQMTSNFIDQFGFNDEKFADQDDIGNVSFDRVSDINFTLNTNESGNIALFEACCKERIQQFDDGGSDEEDIWEEKHIAFTPESQRRSSSGSTDSEESTDSEEEDGTKQDLFESHANTEDKMEVDLNEPPNWSANFDVPMETAHGTNLDSVGSDVWSTEEPMPAKETGWASFSEFTSSLSSTDSLRSNSPVEMETNTEPMDPLSANATGLATQLETPGSVAMEASSDGEEDAENADKVTETVMNGSMKETLSLTVDAKTETAVFKSEEGKLSTSQDASCKYVVEENAEVAEEAPSALQPANSSPEQRTDQRTLLGETSVNGPV", "length": 879, "header": "tr|A0A8V1ABS4-1|A0A8V1ABS4_CHICK Isoform 1 of Protein phosphatase 6 regulatory subunit 3 OS=Gallus gallus OX=9031 GN=PPP6R3 PE=3 SV=1 CANONICAL=A0A8V1ABS4-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A4C7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABS4/entry#A0A8V1A4C7-1", "sequence": { "sequence": "MFWKFDLHSSSHIDTLLEREDVTLKELMDEEDVLQECKAQNRKLIEFLLKSECLEDLVSFIIEEPPQDMDEKIRYKYPNISCELLTSDVSQINDRLGEEESLLMKLYSFLLNESPLNPLLASFFSKVLSILISRKPEQIVDFLKKKHDFVDLVIKHIGTSAIMDLLLRLLTCIEPPQPRQEVLNWLNEERIIQRLVEIVHPSQDEDRHSNASQSLCEIIRLSRDQMLQVQNSSEPDPLLASLEKREIIEQLLSNIFHKEKNESAIVSAIQILLTLLETRRQTFEGHIEICPPGMSNSTYSVNKSVLEAIKARLSSFHELLLEPPKKSVMKTTWGVLDPPVGNTRLNVIRLISSLLQTNTSSVNQELIELNSIGVILDMFFKYTWNNFLHTQVEICIALILASPLESTENGTITDQDSTGDNLLLKHLFLKCQLIERILEAWEMNEKKQAEGGRRHGYMGHLTRIANCIVHSTDKGPNSTLVQQLIKELPEEVRERWETFCTSSLGETNKRNTVDLVTTCHIHSSSDDEIDFKETGFSQDSSLQQAFSDYQMQQMTSNFIDQFGFNDEKFADQDDIGNVSFDRVSDINFTLNTNESGNIALFEACCKERIQQFDDGGSDEEDIWEEKHIAFTPESQRRSSSGSTDSEESTDSEEEDGTKQDLFESHANTEDKMEVDLNEPPNWSANFDVPMETAHGTNLDSVGSDVWSTEEPMPAKETGWASFSEFTSSLSSTDSLRSNSPVEMETNTEPMDPLSANATGLATQLETPGSVAMEASSDGEEDAENADKVTETVMNGSMKETLSLTVDAKTETAVFKSEEGKLSTSQDASCKYVVEENAEVAEEAPSALQPANSSPEQR", "length": 857, "header": "tr|A0A8V1A4C7-1|A0A8V1ABS4_CHICK Computationally mapped isoform of Protein phosphatase 6 regulatory subunit 3 OS=Gallus gallus OX=9031 GN=PPP6R3 PE=3 SV=1 CANONICAL=A0A8V1ABS4-1" }, "locus": { "chromosome": "5", "start_pos": 16116007, "end_pos": 16088212, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010062993.1", "url": "https://www.ensembl.org/id/ENSGALT00010062993.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038899.1", "url": "https://www.ensembl.org/id/ENSGALP00010038899.1" } ] } }, { "isoform_ac": "A0A8V1A6Q9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABS4/entry#A0A8V1A6Q9-1", "sequence": { "sequence": 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3 OS=Gallus gallus OX=9031 GN=PPP6R3 PE=3 SV=1 CANONICAL=A0A8V1ABS4-1" }, "locus": { "chromosome": "5", "start_pos": 16120299, "end_pos": 16085350, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063000.1", "url": "https://www.ensembl.org/id/ENSGALT00010063000.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038900.1", "url": "https://www.ensembl.org/id/ENSGALP00010038900.1" } ] } }, { "isoform_ac": "A0A8V1ABS4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABS4/entry#A0A8V1ABS4-1", "sequence": { "sequence": "MFAVTSMFWKFDLHSSSHIDTLLEREDVTLKELMDEEDVLQECKAQNRKLIEFLLKSECLEDLVSFIIEEPPQDMDEKIRYKYPNISCELLTSDVSQINDRLGEEESLLMKLYSFLLNESPLNPLLASFFSKVLSILISRKPEQIVDFLKKKHDFVDLVIKHIGTSAIMDLLLRLLTCIEPPQPRQEVLNWLNEERIIQRLVEIVHPSQDEDRHSNASQSLCEIIRLSRDQMLQVQNSSEPDPLLASLEKREIIEQLLSNIFHKEKNESAIVSAIQILLTLLETRRQTFEGHIEICPPGMSNSTYSVNKSVLEAIKARLSSFHELLLEPPKKSVMKTTWGVLDPPVGNTRLNVIRLISSLLQTNTSSVNQELIELNSIGVILDMFFKYTWNNFLHTQVEICIALILASPLESTENGTITDQDSTGDNLLLKHLFLKCQLIERILEAWEMNEKKQAEGGRRHGYMGHLTRIANCIVHSTDKGPNSTLVQQLIKELPEEVRERWETFCTSSLGETNKRNTVDLVTTCHIHSSSDDEIDFKETGFSQDSSLQQAFSDYQMQQMTSNFIDQFGFNDEKFADQDDIGNVSFDRVSDINFTLNTNESGNIALFEACCKERIQQFDDGGSDEEDIWEEKHIAFTPESQRRSSSGSTDSEESTDSEEEDGTKQDLFESHANTEDKMEVDLNEPPNWSANFDVPMETAHGTNLDSVGSDVWSTEEPMPAKETGWASFSEFTSSLSSTDSLRSNSPVEMETNTEPMDPLSANATGLATQLETPGSVAMEASSDGEEDAENADKVTETVMNGSMKETLSLTVDAKTETAVFKSEEGKLSTSQDASCKYVVEENAEVAEEAPSALQPANSSPEQRTDQRTLLGETSVNGPV", "length": 879, "header": "tr|A0A8V1ABS4-1|A0A8V1ABS4_CHICK Isoform 1 of Protein phosphatase 6 regulatory subunit 3 OS=Gallus gallus OX=9031 GN=PPP6R3 PE=3 SV=1 CANONICAL=A0A8V1ABS4-1" }, "locus": { "chromosome": "5", "start_pos": 16120299, "end_pos": 16085350, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063008.1", "url": "https://www.ensembl.org/id/ENSGALT00010063008.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038903.1", "url": "https://www.ensembl.org/id/ENSGALP00010038903.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-171319", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-171319", "resource": "Reactome", "description": "Telomere Extension By Telomerase" }, { "id": "R-GGA-204005", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-204005", "resource": "Reactome", "description": "COPII-mediated vesicle transport" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein phosphatase binding", "id": "GO:0019903", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019903", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABS4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABS4" } ], "pmid": "" }, { "name": "protein phosphatase regulator activity", "id": "GO:0019888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019888", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABS4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABS4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABS4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABS4" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABS4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABS4" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABS4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABS4" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABS4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABS4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of signal transduction", "id": "GO:0009966", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009966", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABS4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABS4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 118, "end_pos": 120, "annotation": "n_glycosylation_sequon" }, { "start_pos": 216, "end_pos": 218, "annotation": "n_glycosylation_sequon" }, { "start_pos": 237, "end_pos": 239, "annotation": "n_glycosylation_sequon" }, { "start_pos": 267, "end_pos": 269, "annotation": "n_glycosylation_sequon" }, { "start_pos": 302, "end_pos": 304, "annotation": "n_glycosylation_sequon" }, { "start_pos": 308, "end_pos": 310, "annotation": "n_glycosylation_sequon" }, { "start_pos": 364, "end_pos": 366, "annotation": "n_glycosylation_sequon" }, { "start_pos": 415, "end_pos": 417, "annotation": "n_glycosylation_sequon" }, { "start_pos": 483, "end_pos": 485, "annotation": "n_glycosylation_sequon" }, { "start_pos": 583, "end_pos": 585, "annotation": "n_glycosylation_sequon" }, { "start_pos": 593, "end_pos": 595, "annotation": "n_glycosylation_sequon" }, { "start_pos": 599, "end_pos": 601, "annotation": "n_glycosylation_sequon" }, { "start_pos": 687, "end_pos": 689, "annotation": "n_glycosylation_sequon" }, { "start_pos": 762, "end_pos": 764, "annotation": "n_glycosylation_sequon" }, { "start_pos": 800, "end_pos": 802, "annotation": "n_glycosylation_sequon" }, { "start_pos": 857, "end_pos": 859, "annotation": "n_glycosylation_sequon" }, { "start_pos": 85, "end_pos": 87, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 118, "end_pos": 120 }, { "start_pos": 216, "end_pos": 218 }, { "start_pos": 237, "end_pos": 239 }, { "start_pos": 267, "end_pos": 269 }, { "start_pos": 302, "end_pos": 304 }, { "start_pos": 308, "end_pos": 310 }, { "start_pos": 364, "end_pos": 366 }, { "start_pos": 415, "end_pos": 417 }, { "start_pos": 483, "end_pos": 485 }, { "start_pos": 583, "end_pos": 585 }, { "start_pos": 593, "end_pos": 595 }, { "start_pos": 599, "end_pos": 601 }, { "start_pos": 687, "end_pos": 689 }, { "start_pos": 762, "end_pos": 764 }, { "start_pos": 800, "end_pos": 802 }, { "start_pos": 857, "end_pos": 859 }, { "start_pos": 85, "end_pos": 87 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AES6-1", "uniprot_ac": "A0A8V1AES6", "uniprot_id": "A0A8V1AES6_CHICK", "mass": { "chemical_mass": 139547.0, "monoisotopic_mass": 139547.0 }, "refseq": { "ac": "XP_015134800", "name": "potassium channel subfamily T member 1 isoform X8", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015134800" }, "gene_names": [ { "name": "KCNT1", "type": "recommended", "evidence": [ { "id": "A0A8V1AES6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AES6" } ] }, { "name": "KCNT1", "type": "synonym", "evidence": [ { "id": "XP_015134800", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015134800" } ] }, { "name": "SLACK", "type": "synonym", "evidence": [ { "id": "XP_015134800", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015134800" } ] } ], "protein_names": [ { "name": "Potassium sodium-activated channel subfamily T member 1", "type": "synonym", "evidence": [ { "id": "A0A8V1AES6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AES6/entry#names_and_taxonomy" } ] }, { "name": "potassium channel subfamily T member 1 isoform X8", "type": "synonym", "evidence": [ { "id": "XP_015134800", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015134800" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052548.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015134800", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015134800" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AES6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AES6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "KCNT1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AES6", "locus": { "chromosome": "17", "start_pos": 8817626, "end_pos": 8872388, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027497", "url": "https://www.ensembl.org/id/ENSGALG00010027497" } ] } } ], "crossref": [ { "id": "A0A8V1AES6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AES6", "database": "AlphaFoldDB", "categories": [] }, { "id": "395248", "url": "https://www.ncbi.nlm.nih.gov/gene/395248", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003148", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003148", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003929", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003929", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013099", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013099", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047871", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047871", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A4I3", "url": "https://www.orthodb.org/?gene=A0A8V1A4I3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A9E2", "url": "https://www.orthodb.org/?gene=A0A8V1A9E2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A9E7", "url": "https://www.orthodb.org/?gene=A0A8V1A9E7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A9F1", "url": "https://www.orthodb.org/?gene=A0A8V1A9F1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AES6", "url": "https://www.orthodb.org/?gene=A0A8V1AES6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AET0", "url": "https://www.orthodb.org/?gene=A0A8V1AET0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AGT4", "url": "https://www.orthodb.org/?gene=A0A8V1AGT4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10027", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10027", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10027:SF14", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10027:SF14", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03493", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03493", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07885", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07885", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22614", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22614", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015134800", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015134800", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "29463", "url": "https://www.rhea-db.org/rhea/29463", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1A4I3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4I3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A4I3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4I3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A9E2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9E2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A9E2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9E2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A9E7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9E7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A9E7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9E7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A9F1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9F1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A9F1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9F1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AES6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AES6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AES6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AES6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AET0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AET0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AET0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AET0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGT4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGT4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGT4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGT4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MARAKLKNSPSESNSHVKTVPPATTEDVRGVSPLLPARRMGSLGSDVGQRPHAEDFSMDSSFSQVQVEFYVNENTFKERLKLFFIKNQRSSLRIRLFNFSLKLLTCLLYIVRVLLDNPEEGIGCWECEKQNYTLFNQSTKINWSHIFWVDRKLPLWAVQVSIALISFLETMLLIYLSYKGNIWEQIFRISFILEMINTVPFIITIFWPPLRNLFIPVFLNCWLAKYALENMINDLHRAIQRTQSAMFNQVLILICTLLCLVFTGTCGIQHLERAGEKLSLFKSFYFCIVTFSTVGYGDVTPKIWPSQLLVVIMICVALVVLPLQFEELVYLWMERQKSGGNYSRHRAQTEKHVVLCVSSLKIDLLMDFLNEFYAHPRLQDYYVVILCPTEMDIQVRRVLQIPLWSQRVIYLQGSALKDQDLMRAKMDNGEACFILSSRNEVDRTAADHQTILRAWAVKDFAPNCPLYVQILKPENKFHVKFADHVVCEEECKYAMLALNCVCPATSTLITLLVHTSRGQEGQESPEQWQRMYGRCSGNEVYHIRMGDSKFFMEYEGKSFTYAAFHAHKKYGVCLIGIRREENKSILLNPGPRHIMAASDTCFYINITKEENSAFIFKQAEKQKKKGFAGRGTYDGPSRLPVHSIIASMGTVAMDLQNTECRPTNSSKLALPAENGSGNRRPSIAPVLELADTSSLLPCDLLSDQSEDEMTQSDEEGSAVVEYVKGYPPNSPYIGSSPTLCHLLPEKAPFCCLRLDKGCKHNSFEDAKAYGFKNKLIIVSAETAGNGLYNFIVPLRAYYRSRKELNPIVLLLDNKPEHHFLEAICCFPMVYYMEGTIDNLDSLLQCGIIYADNLVVVDKESTMSAEEDYMADAKTIVNVQTMFRLFPSLSIITELTHPSNMRFMQFRAKDSYSLALSKLEKKERENGSNLAFMFRLPFAAGRVFSISMLDTLLYQSFVKDYMITITRLLLGLDTTPGSGYLCAMKITEDDLWIRTYGRLFQKLCSSSAEIPIGIYRTESHMFATSEPHDIRAQSQISINVEDCEDTKDVKEHWGIKTGHHRNSCSSDQSEHPLLRRKSMQWARRLSRKGNKHSGKTAEWISQQRLSLYRRSERQELSELVKNRMKHLGLPTTGYEDVANLTASDVMNRVNLGYLQDEMNDHQNTLSYVLINPPPDTRLELNDIVYLIRSDPLAHVANDGHSRKSSCSNKLGPCNPETRDETQL", "length": 1222, "header": "tr|A0A8V1AES6-1|A0A8V1AES6_CHICK Isoform 1 of Potassium sodium-activated channel subfamily T member 1 OS=Gallus gallus OX=9031 GN=KCNT1 PE=4 SV=1 CANONICAL=A0A8V1AES6-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A4I3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AES6/entry#A0A8V1A4I3-1", "sequence": { "sequence": "MTELESEVLPLPPRYRFRDLLLGDQSFQSDDRVQVEFYVNENTFKERLKLFFIKNQRSSLRIRLFNFSLKLLTCLLYIVRVLLDNPEEGIGCWECEKQNYTLFNQSTKINWSHIFWVDRKLPLWAVQVSIALISFLETMLLIYLSYKGNIWEQIFRISFILEMINTVPFIITIFWPPLRNLFIPVFLNCWLAKYALENMINDLHRAIQRTQSAMFNQVLILICTLLCLVFTGTCGIQHLERAGEKLSLFKSFYFCIVTFSTVGYGDVTPKIWPSQLLVVIMICVALVVLPLQFEELVYLWMERQKSGGNYSRHRAQTEKHVVLCVSSLKIDLLMDFLNEFYAHPRLQDYYVVILCPTEMDIQVRRVLQIPLWSQRVIYLQGSALKDQDLMRAKMDNGEACFILSSRNEVDRTAADHQTILRAWAVKDFAPNCPLYVQILKPENKFHVKFADHVVCEEECKYAMLALNCVCPATSTLITLLVHTSRGQEGQESPEQWQRMYGRCSGNEVYHIRMGDSKFFMEYEGKSFTYAAFHAHKKYGVCLIGIRREENKSILLNPGPRHIMAASDTCFYINITKEENSAFIFKQAEKQKKKGFAGRGTYDGPSRLPVHSIIASMGTVAMDLQNTECRPTNSSKLALPAENGSGNRRPSIAPVLELADTSSLLPCDLLSDQSEDEMTQSDEEGSAVVEYVKGYPPNSPYIGSSPTLCHLLPEKAPFCCLRLDKGCKHNSFEDAKAYGFKNKLIIVSAETAGNGLYNFIVPLRAYYRSRKELNPIVLLLDNKPEHHFLEAICCFPMVYYMEGTIDNLDSLLQCGIIYADNLVVVDKESTMSAEEDYMADAKTIVNVQTMFRLFPSLSIITELTHPSNMRFMQFRAKDSYSLALSKLEKSFVKDYMITITRLLLGLDTTPGSGYLCAMKITEDDLWIRTYGRLFQKLCSSSAEIPIGIYRTESHMFATSEPHDIRAQSQISINVEDCEDTKDVKEHWGIKTGHHRNSCSSDQSEHPLLRRKSMQWARRLSRKGNKHSGKTAEWISQQRLSLYRRSERQELSELVKNRMKHLGLPTTGYDEMNDHQNTLSYVLINPPPDTRLELNDIVYLIRSDPLAHVANDGHSRKSSCSNKLGPCNPETRDETQL", "length": 1135, "header": "tr|A0A8V1A4I3-1|A0A8V1AES6_CHICK Computationally mapped isoform of Potassium sodium-activated channel subfamily T member 1 OS=Gallus gallus OX=9031 GN=KCNT1 PE=4 SV=1 CANONICAL=A0A8V1AES6-1" }, "locus": { "chromosome": "17", "start_pos": 8863502, "end_pos": 8820494, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066647.1", "url": "https://www.ensembl.org/id/ENSGALT00010066647.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040806.1", "url": "https://www.ensembl.org/id/ENSGALP00010040806.1" } ] } }, { "isoform_ac": "A0A8V1A9E2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AES6/entry#A0A8V1A9E2-1", "sequence": { "sequence": "MARAKLKNSPSESNSHVKTVPPATTEDVRGVSPLLPARRMGSLGSDVGQRYCGAAVVRGLGKVQVEFYVNENTFKERLKLFFIKNQRSSLRIRLFNFSLKLLTCLLYIVRVLLDNPEEGIGCWECEKQNYTLFNQSTKINWSHIFWVDRKLPLWAVQVSIALISFLETMLLIYLSYKGNIWEQIFRISFILEMINTVPFIITIFWPPLRNLFIPVFLNCWLAKYALENMINDLHRAIQRTQSAMFNQVLILICTLLCLVFTGTCGIQHLERAGEKLSLFKSFYFCIVTFSTVGYGDVTPKIWPSQLLVVIMICVALVVLPLQFEELVYLWMERQKSGGNYSRHRAQTEKHVVLCVSSLKIDLLMDFLNEFYAHPRLQDYYVVILCPTEMDIQVRRVLQIPLWSQRVIYLQGSALKDQDLMRAKMDNGEACFILSSRNEVDRTAADHQTILRAWAVKDFAPNCPLYVQILKPENKFHVKFADHVVCEEECKYAMLALNCVCPATSTLITLLVHTSRGEGQESPEQWQRMYGRCSGNEVYHIRMGDSKFFMEYEGKSFTYAAFHAHKKYGVCLIGIRREENKSILLNPGPRHIMAASDTCFYINITKEENSAFIFKQAEKQKKKGFAGRGTYDGPSRLPVHSIIASMGTVAMDLQNTECRPTNSSKLALPAENGSGNRRPSIAPVLELADTSSLLPCDLLSDQSEDEMTQSDEEGSAVVEYVKGYPPNSPYIGSSPTLCHLLPEKAPFCCLRLDKGCKHNSFEDAKAYGFKNKLIIVSAETAGNGLYNFIVPLRAYYRSRKELNPIVLLLDNKPEHHFLEAICCFPMVYYMEGTIDNLDSLLQCGIIYADNLVVVDKESTMSAEEDYMADAKTIVNVQTMFRLFPSLSIITELTHPSNMRFMQFRAKDSYSLALSKLEKKERENGSNLAFMFRLPFAAGRVFSISMLDTLLYQSFVKDYMITITRLLLGLDTTPGSGYLCAMKITEDDLWIRTYGRLFQKLCSSSAEIPIGIYRTESHMFATSESQISINVEDCEDTKDVKEHWGIKTGHHRNSCSSDQSEHPLLRRKSMQWARRLSRKGNKHSGKTAEWISQQRLSLYRRSERQELSELVKNRMKHLGLPTTGYDEMNDHQNTLSYVLINPPPDTRLELNDIVYLIRSDPLAHVANDGHSRKSSCSNKLGPCNPETRDETQL", "length": 1191, "header": "tr|A0A8V1A9E2-1|A0A8V1AES6_CHICK Computationally mapped isoform of Potassium sodium-activated channel subfamily T member 1 OS=Gallus gallus OX=9031 GN=KCNT1 PE=4 SV=1 CANONICAL=A0A8V1AES6-1" }, "locus": { "chromosome": "17", "start_pos": 8846268, "end_pos": 8820494, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066635.1", "url": "https://www.ensembl.org/id/ENSGALT00010066635.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040798.1", "url": "https://www.ensembl.org/id/ENSGALP00010040798.1" } ] } }, { "isoform_ac": "A0A8V1A9E7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AES6/entry#A0A8V1A9E7-1", "sequence": { "sequence": "MARAKLKNSPSESNSHVKTVPPATTEDVRGVSPLLPARRMGSLGSDVGQRVQVEFYVNENTFKERLKLFFIKNQRSSLRIRLFNFSLKLLTCLLYIVRVLLDNPEEGIGCWECEKQNYTLFNQSTKINWSHIFWVDRKLPLWAVQVSIALISFLETMLLIYLSYKGNIWEQIFRISFILEMINTVPFIITIFWPPLRNLFIPVFLNCWLAKYALENMINDLHRAIQRTQSAMFNQVLILICTLLCLVFTGTCGIQHLERAGEKLSLFKSFYFCIVTFSTVGYGDVTPKIWPSQLLVVIMICVALVVLPLQFEELVYLWMERQKSGGNYSRHRAQTEKHVVLCVSSLKIDLLMDFLNEFYAHPRLQDYYVVILCPTEMDIQVRRVLQIPLWSQRVIYLQGSALKDQDLMRAKMDNGEACFILSSRNEVDRTAADHQTILRAWAVKDFAPNCPLYVQILKPENKFHVKFADHVVCEEECKYAMLALNCVCPATSTLITLLVHTSRGQEGQESPEQWQRMYGRCSGNEVYHIRMGDSKFFMEYEGKSFTYAAFHAHKKYGVCLIGIRREENKSILLNPGPRHIMAASDTCFYINITKEENSAFIFKQAEKQKKKGFAGRGTYDGPSRLPVHSIIASMGTVAMDLQNTECRPTNSSKLALPAENGSGNRRPSIAPVLELADTSSLLPCDLLSDQSEDEMTQSDEEGSAVVEYVKGYPPNSPYIGSSPTLCHLLPEKAPFCCLRLDKGCKHNSFEDAKAYGFKNKLIIVSAETAGNGLYNFIVPLRAYYRSRKELNPIVLLLDNKPEHHFLEAICCFPMVYYMEGTIDNLDSLLQCGIIYADNLVVVDKESTMSAEEDYMADAKTIVNVQTMFRLFPSLSIITELTHPSNMRFMQFRAKDSYSLALSKLEKKERENGSNLAFMFRLPFAAGRVFSISMLDTLLYQSFVKDYMITITRLLLGLDTTPGSGYLCAMKITEDDLWIRTYGRLFQKLCSSSAEIPIGIYRTESHMFATSEPHDIRAQISINVEDCEDTKDVKEHWGIKTGHHRNSCSSDQSEHPLLRRKSMQWARRLSRKGNKHSGKTAEWISQQRLSLYRRSERQELSELVKNRMKHLGLPTTGYEDVANLTASDVMNRVNLGYLQDEMNDHQNTLSYVLINPPPDTRLELNDIVYLIRSDPLAHVANDGHSRKSSCSNKLGPCNPETRDETQL", "length": 1206, "header": "tr|A0A8V1A9E7-1|A0A8V1AES6_CHICK Computationally mapped isoform of Potassium sodium-activated channel subfamily T member 1 OS=Gallus gallus OX=9031 GN=KCNT1 PE=4 SV=1 CANONICAL=A0A8V1AES6-1" }, "locus": { "chromosome": "17", "start_pos": 8846268, "end_pos": 8820494, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066642.1", "url": "https://www.ensembl.org/id/ENSGALT00010066642.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040803.1", "url": "https://www.ensembl.org/id/ENSGALP00010040803.1" } ] } }, { "isoform_ac": "A0A8V1A9F1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AES6/entry#A0A8V1A9F1-1", "sequence": { "sequence": "MTELESEVLPLPPRYRFRDLLLGDQSFQSDDRVQVEFYVNENTFKERLKLFFIKNQRSSLRIRLFNFSLKLLTCLLYIVRVLLDNPEEGIGCWECEKQNYTLFNQSTKINWSHIFWVDRKLPLWAVQVSIALISFLETMLLIYLSYKGNIWEQIFRISFILEMINTVPFIITIFWPPLRNLFIPVFLNCWLAKYALENMINDLHRAIQRTQSAMFNQVLILICTLLCLVFTGTCGIQHLERAGEKLSLFKSFYFCIVTFSTVGYGDVTPKIWPSQLLVVIMICVALVVLPLQFEELVYLWMERQKSGGNYSRHRAQTEKHVVLCVSSLKIDLLMDFLNEFYAHPRLQDYYVVILCPTEMDIQVRRVLQIPLWSQRVIYLQGSALKDQDLMRAKMDNGEACFILSSRNEVDRTAADHQTILRAWAVKDFAPNCPLYVQILKPENKFHVKFADHVVCEEECKYAMLALNCVCPATSTLITLLVHTSRGQEGQESPEQWQRMYGRCSGNEVYHIRMGDSKFFMEYEGKSFTYAAFHAHKKYGVCLIGIRREENKSILLNPGPRHIMAASDTCFYINITKEENSAFIFKQAEKQKKKGFAGRGTYDGPSRLPVHSIIASMVAMDLQNTECRPTNSSKLALPAENGSGNRRPSIAPVLELADTSSLLPCDLLSDQSEDEMTQSDEEGSAVVEYVKGYPPNSPYIGSSPTLCHLLPEKAPFCCLRLDKGCKHNSFEDAKAYGFKNKLIIVSAETAGNGLYNFIVPLRAYYRSRKELNPIVLLLDNKPEHHFLEAICCFPMVYYMEGTIDNLDSLLQCGIIYADNLVVVDKESTMSAEEDYMADAKTIVNVQTMFRLFPSLSIITELTHPSNMRFMQFRAKDSYSLALSKLEKKERENGSNLAFMFRLPFAAGRVFSISMLDTLLYQSFVKDYMITITRLLLGLDTTPGSGYLCAMKITEDDLWIRTYGRLFQKLCSSSAEIPIGIYRTESHMFATSEPHDIRAQSQISINVEDCEDTKDVKEHWGIKTGHHRNSCSSDQSEHPLLRRKSMQWARRLSRKGNKHSGKTAEWISQQRLSLYRRSERQELSELVKNRMKHLGLPTTGYDEMNDHQNTLSYVLINPPPDTRLELNDIVYLIRSDPLAHVANDGHSRKSSCSNKLGPCNPETRDETQL", "length": 1167, "header": "tr|A0A8V1A9F1-1|A0A8V1AES6_CHICK Computationally mapped isoform of Potassium sodium-activated channel subfamily T member 1 OS=Gallus gallus OX=9031 GN=KCNT1 PE=4 SV=1 CANONICAL=A0A8V1AES6-1" }, "locus": { "chromosome": "17", "start_pos": 8863502, "end_pos": 8820494, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066650.1", "url": "https://www.ensembl.org/id/ENSGALT00010066650.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040808.1", "url": "https://www.ensembl.org/id/ENSGALP00010040808.1" } ] } }, { "isoform_ac": "A0A8V1AES6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AES6/entry#A0A8V1AES6-1", "sequence": { "sequence": "MARAKLKNSPSESNSHVKTVPPATTEDVRGVSPLLPARRMGSLGSDVGQRPHAEDFSMDSSFSQVQVEFYVNENTFKERLKLFFIKNQRSSLRIRLFNFSLKLLTCLLYIVRVLLDNPEEGIGCWECEKQNYTLFNQSTKINWSHIFWVDRKLPLWAVQVSIALISFLETMLLIYLSYKGNIWEQIFRISFILEMINTVPFIITIFWPPLRNLFIPVFLNCWLAKYALENMINDLHRAIQRTQSAMFNQVLILICTLLCLVFTGTCGIQHLERAGEKLSLFKSFYFCIVTFSTVGYGDVTPKIWPSQLLVVIMICVALVVLPLQFEELVYLWMERQKSGGNYSRHRAQTEKHVVLCVSSLKIDLLMDFLNEFYAHPRLQDYYVVILCPTEMDIQVRRVLQIPLWSQRVIYLQGSALKDQDLMRAKMDNGEACFILSSRNEVDRTAADHQTILRAWAVKDFAPNCPLYVQILKPENKFHVKFADHVVCEEECKYAMLALNCVCPATSTLITLLVHTSRGQEGQESPEQWQRMYGRCSGNEVYHIRMGDSKFFMEYEGKSFTYAAFHAHKKYGVCLIGIRREENKSILLNPGPRHIMAASDTCFYINITKEENSAFIFKQAEKQKKKGFAGRGTYDGPSRLPVHSIIASMGTVAMDLQNTECRPTNSSKLALPAENGSGNRRPSIAPVLELADTSSLLPCDLLSDQSEDEMTQSDEEGSAVVEYVKGYPPNSPYIGSSPTLCHLLPEKAPFCCLRLDKGCKHNSFEDAKAYGFKNKLIIVSAETAGNGLYNFIVPLRAYYRSRKELNPIVLLLDNKPEHHFLEAICCFPMVYYMEGTIDNLDSLLQCGIIYADNLVVVDKESTMSAEEDYMADAKTIVNVQTMFRLFPSLSIITELTHPSNMRFMQFRAKDSYSLALSKLEKKERENGSNLAFMFRLPFAAGRVFSISMLDTLLYQSFVKDYMITITRLLLGLDTTPGSGYLCAMKITEDDLWIRTYGRLFQKLCSSSAEIPIGIYRTESHMFATSEPHDIRAQSQISINVEDCEDTKDVKEHWGIKTGHHRNSCSSDQSEHPLLRRKSMQWARRLSRKGNKHSGKTAEWISQQRLSLYRRSERQELSELVKNRMKHLGLPTTGYEDVANLTASDVMNRVNLGYLQDEMNDHQNTLSYVLINPPPDTRLELNDIVYLIRSDPLAHVANDGHSRKSSCSNKLGPCNPETRDETQL", "length": 1222, "header": "tr|A0A8V1AES6-1|A0A8V1AES6_CHICK Isoform 1 of Potassium sodium-activated channel subfamily T member 1 OS=Gallus gallus OX=9031 GN=KCNT1 PE=4 SV=1 CANONICAL=A0A8V1AES6-1" }, "locus": { "chromosome": "17", "start_pos": 8846268, "end_pos": 8820494, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066638.1", "url": "https://www.ensembl.org/id/ENSGALT00010066638.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040799.1", "url": "https://www.ensembl.org/id/ENSGALP00010040799.1" } ] } }, { "isoform_ac": "A0A8V1AET0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AES6/entry#A0A8V1AET0-1", "sequence": { "sequence": 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"length": 1144, "header": "tr|A0A8V1AGT4-1|A0A8V1AES6_CHICK Computationally mapped isoform of Potassium sodium-activated channel subfamily T member 1 OS=Gallus gallus OX=9031 GN=KCNT1 PE=4 SV=1 CANONICAL=A0A8V1AES6-1" }, "locus": { "chromosome": "17", "start_pos": 8837054, "end_pos": 8820494, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066631.1", "url": "https://www.ensembl.org/id/ENSGALT00010066631.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040797.1", "url": "https://www.ensembl.org/id/ENSGALP00010040797.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AES6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AES6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "potassium channel activity", "id": "GO:0005267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005267", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AES6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AES6" } ], "pmid": "" }, { "name": "outward rectifier potassium channel activity", "id": "GO:0015271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015271", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AES6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AES6" } ], "pmid": "" }, { "name": "intracellular sodium-activated potassium channel activity", "id": "GO:0005228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005228", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AES6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AES6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": 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This record is derived from a genomic sequence (NC_052559.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_025000208", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025000208" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AC97", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC97" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FGF22", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC97", "locus": { "chromosome": "28", "start_pos": 3153770, "end_pos": 3149571, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027553", "url": "https://www.ensembl.org/id/ENSGALG00010027553" } ] } } ], "crossref": [ { "id": "A0A8V1AC97", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AC97", "database": 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"UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC51/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052539.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_422429.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_422429", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_422429" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AC51", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC51" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "HECTD3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC51", "locus": { "chromosome": "8", "start_pos": 20605747, "end_pos": 20626397, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010025940", "url": "https://www.ensembl.org/id/ENSGALG00010025940" } ] } } ], "crossref": [ { "id": "A0A8V1AC51", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AC51", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd08666", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08666", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "424589", "url": "https://www.ncbi.nlm.nih.gov/gene/424589", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000569", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000569", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004939", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004939", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035983", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035983", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042469", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042469", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "LMCKHAD", "url": "https://omabrowser.org/oma/group/LMCKHAD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A4S4", "url": "https://www.orthodb.org/?gene=A0A8V1A4S4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A9U3", "url": "https://www.orthodb.org/?gene=A0A8V1A9U3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AC51", "url": "https://www.orthodb.org/?gene=A0A8V1AC51", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46654", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46654", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46654:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46654:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00632", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00632", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03256", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03256", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-983168", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983168", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_422429", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_422429", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1A4S4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4S4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A4S4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4S4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A9U3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9U3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A9U3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9U3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AC51", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC51", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AC51-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC51-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRAGGEAPHQVLGRLRFLLQCSECFRRARPLPAALCYVPREVQYKICKDPSAAASSRSLLSVWDSPGPARGSKRAARATIEVRKGGCLRATGEEYCNSAGLWVKLSKEQLEEYKSGCDLEEGWVLVCKHAEGGDRLVPVESTERIQRQQQLFGVDYKPVIRWEQVVDLTYSLRLGAKPKPMDQDEAAVEKLRFVPPTWTYECDEDLVHFLYDHIGKEDENLGSVKQYVDSIDVSSYTEDFNVSCLTDSHADTYWESDGSQGQHWVRLNMKKGTIVKKLLLTVDTTDENFMPKRVAVYGGEGDNLKKLNDVGIDESYIGDVCVLEDMTTHLPVIEIRIVECRDDGIDVRLRGIKIKSSRQRDLGLSADMFQLANLVRYPRLEGTDPDLLYRRAVLIQRFIKLLDSVLHHLVPAWDHTVGTFSKLKHIKQFLLLSKRRTALITQCLKDSETSKPNFMPRLYINRRLAMEHRDNPALDPSCKNAVFTQVFEGLKPSDKFEKPLDYRWPLRYDQWWECKFIAEGIIDQGGGFRDSLADMSEELCPSSADTPVPLPFFVRTSNQGNSTGEARDMYVPNPSCKDFPKYEWIGQIMGAALRGKEFLVLALPGFVWKQLTGEEVSWSKDFAAVDSVLVKLLEVMEVMDRDTFEFKFGNELTYTTVLSDQRMVELIPNGSNTVVRYEDRKEFIRLVQKARLEESKEQIMAMQAGLLKVVPQAVLDLLTWQELEKKVCGDPEVTVDALKKLTRFEDFEPLDTRVQYFWEALNNFTNEDRSRFLRFVTGRSRLPARIYIYPDKLGSETTDALPESSTCSSTLFLPNYATAKVCEEKLRYAAYNCVAIDTDMSPWEE", "length": 845, "header": "tr|A0A8V1AC51-1|A0A8V1AC51_CHICK Isoform 1 of HECT domain E3 ubiquitin protein ligase 3 OS=Gallus gallus OX=9031 GN=HECTD3 PE=4 SV=1 CANONICAL=A0A8V1AC51-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A4S4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC51/entry#A0A8V1A4S4-1", "sequence": { "sequence": "MRAGGEAPHQVLGRLRFLLQCSECFRRARPLPAALCYVPREVQYKICKDPSAAASSRSLLSVWDGPGPARGSKRATIEVRKGGCLRATGEEYRNSAGLWVKLRKEHLEEHGVCRELEEGWVLAQRFGDGGDKLVPVERIQQQQQTFGTDYKPAASWEQVVDLMYSMQLGEKPVPVEPDEAVVQKLRSMPPNWSYEQDMELGRFLYDVTERDEHCKDCVKDHLNGIEVSSQLDDFKVSHLTDNQGDTYWESSGSPGQHWVRLHMKKGSVIKKLWLMLNANINSYVPRRVAVYGGPANRLQHLRTVLINENSYQDVCILRDMKTHVPVLEIRILECREQGYNVRLRGIKFKSFWERDLNLNADMFQMAQLVRYPLLEGVDTDVLYRRAVVIQRFTQLLDSVLGYLIPISDESDSTFSVLRGMKPFLQLCKLSKTLVTHCLQSSESSPPCMLPKLLINRQLAREHRAHPELDPSGRNTVFTQVYENLKPSKTNNHLLNYRWPQTHSQWWECVFTTEGIIDNGGGFRDCLTDISEELCPSSGDVPVPLPFFVRTSNQGNSSSDTRDMYVPNPSCKDFPKYEWIGQLMGAALRSKEILVLALPSLVWKQLSGEEVIWSKDFAAVDVELVKLLQMLEEVDREAFNFMFGKELTYTTVRSDQRVVELIPKGSSTVVRFEDRKEFIRLVQKARLEESKEQVEAIRAGLLRVVPQAVLDLLTWQQLEKKVCGNPEVTVDELKKFVTFEDFDSSHVQQFWDALNNFTSEDLSRFLKFVTGRSRLPVQLTIYPDRSIPERLDMMPEASTCSCTLFLPKYSSVKTCEELLRYAVYNCMSIDTDKDNWD", "length": 836, "header": "tr|A0A8V1A4S4-1|A0A8V1AC51_CHICK Computationally mapped isoform of HECT domain E3 ubiquitin protein ligase 3 OS=Gallus gallus OX=9031 GN=HECTD3 PE=4 SV=1 CANONICAL=A0A8V1AC51-1" }, "locus": { "chromosome": "8", "start_pos": 20626123, "end_pos": 20605771, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063244.1", "url": "https://www.ensembl.org/id/ENSGALT00010063244.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039046.1", "url": "https://www.ensembl.org/id/ENSGALP00010039046.1" } ] } }, { "isoform_ac": "A0A8V1A9U3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC51/entry#A0A8V1A9U3-1", "sequence": { "sequence": "MRAGGEAPHQVLGRLRFLLQCSECFRRARPLPAALCYVPREVQYKICKDPSAAASSRSLLSVWDSPGPARGSKRAARATIEVRKGGCLRATGEEYCNSAGLWVKLSKEHLEEHGVCRELEEGWVLAQRFGDGGDKLVPVERIQQQQQTFGTDYKPAASWEQVVDLMYSMQLGEKPVPVEPDEAVVQKLRSMPPNWSYEQDMELGRFLYDVTERDEHCKDCVKDHLNGIEVSSQLDDFKVSHLTDNQGDTYWESSGSPGQHWVRLHMKKGSVIKKLWLMLNANINSYVPRRVAVYGGPANRLQHLRTVLINENSYQDVCILRDMKTHVPVLEIRILECREQGYNVRLRGIKFKSFWERDLNLNADMFQMAQLVRYPLLEGVDTDVLYRRAVVIQRFTQLLDSVLGYLIPISDESDSTFSVLRGMKPFLQLCKLSKTLVTHCLQSSESSPPCMLPKLLINRQLAREHRAHPELDPSGRNTVFTQVYENLKPSKTNNHLLNYRWPQTHSQWWECVFTTEGIIDNGGGFRDCLTDISEELCPSSGDVPVPLPFFVRTSNQGNSSSDTRDMYVPNPSCKDFPKYEWIGQLMGAALRSKEILVLALPSLVWKQLSGEEVIWSKDFAAVDVELVKLLQMLEEVDREAFNFMFGKELTYTTVRSDQRVVELIPKGSSTVVRFEDRKEFIRLVQKARLEESKEQVEAIRAGLLRVVPQAVLDLLTWQQLEKKVCGNPEVTVDELKKFVTFEDFDSSHVQQFWDALNNFTSEDLSRFLKFVTGRSRLPVQLTIYPDRSIPERLDMMPEASTCSCTLFLPKYSSVKTCEELLRYAVYNCMSIDTDKDNWD", "length": 839, "header": "tr|A0A8V1A9U3-1|A0A8V1AC51_CHICK Computationally mapped isoform of HECT domain E3 ubiquitin protein ligase 3 OS=Gallus gallus OX=9031 GN=HECTD3 PE=4 SV=1 CANONICAL=A0A8V1AC51-1" }, "locus": { "chromosome": "8", "start_pos": 20626123, "end_pos": 20605771, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063240.1", "url": "https://www.ensembl.org/id/ENSGALT00010063240.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039042.1", "url": "https://www.ensembl.org/id/ENSGALP00010039042.1" } ] } }, { "isoform_ac": "A0A8V1AC51-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC51/entry#A0A8V1AC51-1", "sequence": { "sequence": "MRAGGEAPHQVLGRLRFLLQCSECFRRARPLPAALCYVPREVQYKICKDPSAAASSRSLLSVWDSPGPARGSKRAARATIEVRKGGCLRATGEEYCNSAGLWVKLSKEQLEEYKSGCDLEEGWVLVCKHAEGGDRLVPVESTERIQRQQQLFGVDYKPVIRWEQVVDLTYSLRLGAKPKPMDQDEAAVEKLRFVPPTWTYECDEDLVHFLYDHIGKEDENLGSVKQYVDSIDVSSYTEDFNVSCLTDSHADTYWESDGSQGQHWVRLNMKKGTIVKKLLLTVDTTDENFMPKRVAVYGGEGDNLKKLNDVGIDESYIGDVCVLEDMTTHLPVIEIRIVECRDDGIDVRLRGIKIKSSRQRDLGLSADMFQLANLVRYPRLEGTDPDLLYRRAVLIQRFIKLLDSVLHHLVPAWDHTVGTFSKLKHIKQFLLLSKRRTALITQCLKDSETSKPNFMPRLYINRRLAMEHRDNPALDPSCKNAVFTQVFEGLKPSDKFEKPLDYRWPLRYDQWWECKFIAEGIIDQGGGFRDSLADMSEELCPSSADTPVPLPFFVRTSNQGNSTGEARDMYVPNPSCKDFPKYEWIGQIMGAALRGKEFLVLALPGFVWKQLTGEEVSWSKDFAAVDSVLVKLLEVMEVMDRDTFEFKFGNELTYTTVLSDQRMVELIPNGSNTVVRYEDRKEFIRLVQKARLEESKEQIMAMQAGLLKVVPQAVLDLLTWQELEKKVCGDPEVTVDALKKLTRFEDFEPLDTRVQYFWEALNNFTNEDRSRFLRFVTGRSRLPARIYIYPDKLGSETTDALPESSTCSSTLFLPNYATAKVCEEKLRYAAYNCVAIDTDMSPWEE", "length": 845, "header": "tr|A0A8V1AC51-1|A0A8V1AC51_CHICK Isoform 1 of HECT domain E3 ubiquitin protein ligase 3 OS=Gallus gallus OX=9031 GN=HECTD3 PE=4 SV=1 CANONICAL=A0A8V1AC51-1" }, "locus": { "chromosome": "8", "start_pos": 20626123, "end_pos": 20615366, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063238.1", "url": "https://www.ensembl.org/id/ENSGALT00010063238.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039040.1", "url": "https://www.ensembl.org/id/ENSGALP00010039040.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-983168", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983168", "resource": "Reactome", "description": "Antigen processing: Ubiquitination & Proteasome degradation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8W4FAH5-1", "protein_name": "E3 ubiquitin-protein ligase HECTD3", "gene_name": "HECTD3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAGPGPGAALESPRQLLGRVRFLAEAAKSLRAGRPLPAALAFVPREVLYKLYKDPAGPSRVLLPVWEAEGLGLRVGAAGPAPGTGSGPLRAARDSIELRRGACVRTTGEELCNGHGLWVKLTKEQLAEHLGDCGLDEGWLLVCRPAEGGARLVPIDTPDHLQRQQQLFGVDYRPVLRWEQVVDLTYSHRLGSKPQPAKAYTEAVQRLLYVPPTWTYECDEDLIHFLYDHLGKEDENLGSVKQYVESIDVSSYTEEFNVSCLTDSNADTYWESDGSQCQHWVRLTMKKGTIVKKLLLTVDTTDDNFMPKRVVVYGGEGDNLKKLSDVSIDETLIGDVCVLEDMTVHLPVIEIRIVECRDDGIDVRLRGVKIKSSRQRELGLNADLFQPTSLVRYPRLEGTDPEVLYRRAVLLQRFIKILDSVLHHLVPAWDHTLGTFSEIKQVKQFLLLSRQRPGLVTQCLRDSESSKPSFMPRLYINRRLAMEHRACPSRDPACKNAVFTQVYEGLKPSDKYEKPLDYRWPMRYDQWWECKFIAEGIIDQGGGFRDSLADMSEELCPSSADTPVPLPFFVRTANQGNGTGEARDMYVPNPSCRDFAKYEWIGQLMGAALRGKEFLVLALPGFVWKQLSGEEVSWSKDFPAVDSVLVKLLEVMEGMDKETFEFKFGKELTFTTVLSDQQVVELVPGGAGIVVGYEDRSRFVQLVQKARLEESKEQVAAMQAGLLKVVPQAVLDLLTWQELEKKVCGDPEVTVDALRKLTRFEDFEPSDTRVQYFWEALNNFTNEDRSRFLRFVTGRSRLPARIYIYPDKLGYETTDALPESSTCSSTLFLPHYASAKVCEEKLRYAAYNCVAIDTDMSPWEE", "length": 861 }, "evidence": [ { "id": "A0A8V1AC51", "url": "https://omabrowser.org/oma/group/A0A8V1AC51/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1LVZ9-1", "protein_name": "E3 ubiquitin-protein ligase HECTD3", "gene_name": "Hectd3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGPGPGAALESPRQLLGRVRFLAEAARSLRAGLPLPAALAFVPREVLYKLYKDPAGPSRVLLPVWEAEGLGLRVGAAGPAPGTGSGPLRAARDSIELRRGACVRTTGEELCNGHGLWVKLTKEQLAEHLSDCSLDEGWLLVCRPAEGGARLVPIDTPDHLQRQQQLFGVDYRPVLRWEQVVDLTYSHRLGSRPQPAEAYTEAVQRLLYVPPTWTYECDEDLIHFLYDHLGKEDENLGSVKQYVESIDVSSYTEEFNVSCLTDSNADTYWESDGSQCQHWVRLTMKKGTIVKKLLLTVDTTDDNFMPKRVVVYGGEGDNLKKLSDVNIDETLIGDVCVLEDMTVHLPVIEIRIVECRDDGIDVRLRGVKIKSSRQRELGLNADLFQPASLVRYPRLEGTDPEVLYRRAVLLQRFIKILDSVLHHLVPAWDHTLGTFSEIKQVKQFLLLSRQRPSLVTQCLRDSESSKPSFMPRLYINRRLAMEHRACPSRDPACKNAVFTQVYEGLKPSDKYEKPLDYRWPMRYDQWWECKFIAEGIIDQGGGFRDSLADMSEELCPSSADTPVPLPFFVRTANQGNGTGEARDMYVPNPSCRDFAKYEWIGQLMGAALRGKEFLVLALPGFVWKQLSGEEVSWSKDFPAVDSVLVKLLEVMEGVDKETFEFKFGKELTFTTVLSDQQVVELIPGGTGIVVGYEDRLRFIQLVQKARLEESKEQVAAMQAGLLKVVPQAVLDLLTWQELEKKVCGDPEVTVDALRKLTRFEDFEPSDTRVQYFWEALNNFTNEDRSRFLRFVTGRSRLPARIYIYPDKLGYETTDALPESSTCSSTLFLPHYASAKVCEEKLRYAAYNCVAIDTDMSPWEE", "length": 861 }, "evidence": [ { "id": "A0A8V1AC51", "url": "https://omabrowser.org/oma/group/A0A8V1AC51/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1MJS5-1", "protein_name": "E3 ubiquitin-protein ligase HECTD3", "gene_name": "HECTD3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAGPGPGAALESPRQLLGRVRFLAEAAKSLRAGRPLPAALAFVPREVLYKLYKDPAGPSRVLLPVWEAEGLGLRVGATGPAPGTGSGALRAARDSIELRRGACVRTTGEELCNGHGLWVKLTKEQLAEHLGDCGLDEGWLLVCRPAEGGARLVPIDTPDHLQRQQQLFGVDYRPVLRWEQVVDLTYSHRLGSRPQPAEAYTEAVQRLLYVPPTWTYECDEDLIHFLYDHLGKEDENLGSVKQYVESIDVSSYTEEFNVSCLTDSNADTYWESDGSQCQHWVRLTMKKGTIVKKLLLTVDTTDDNFMPKRVVVYGGEGDNLKKLSDVSIDETLIGDVCVLEDMTVHLPIIEIRIVECRDDGIDVRLRGVKIKSSRQRELGLNADLFQPTNLVRYPRLEGTDPEVLYRRAVLLQRFIKILDSVLHHLVPAWDHTLGTFSEIKQVKQFLLLSRQRPGLVAQCLRDSESSKPSFMPRLYINRRLAMEHRACPLRDPACKNAVFTQVYEGLKPSDKYEKPLDYRWPMRYDQWWECKFIAEGIIDQGGGFRDSLADMSEELCPSSADTPVPLPFFVRTANQGNGTGEARDMYVPNPSCRDFAKYEWIGQLMGAALRGKEFLVLALPGFVWKQLSGEEVSWSKDFPAVDSVLVKLLEVMEGMDKETFEFKFGKELTFTTVLSDQQVVELIPGGSGIVVGYEDRSRFIQLVQKARLEESKEQVAAMQAGLLKVVPQAVLDLLTWQELEKKVCGDPEVTVDALRKLTRFEDFEPSDTRVQYFWEALNNFTNEDRSRFLRFVTGRSRLPARIYIYPDKLGYETTDALPESSTCSSTLFLPHYASAKVCEEKLRYAAYNCVAIDTDMSPWEE", "length": 861 }, "evidence": [ { "id": "A0A8V1AC51", "url": "https://omabrowser.org/oma/group/A0A8V1AC51/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1QF19-1", "protein_name": "2.3.2.26", "gene_name": "hectd3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSPDDNPHTLLGRIRFLNRCIECFRKSEPLPESLCYVAKEVCYKICKDSSSGSTSASSSTAGNSGGKSVVSVWDSPHQAPHKKSCRCNIEPKKGTCIRTTGEEYCNSHGLWVKINKEQLEEYRAGVDIEEGWILVCKHTEGGDRLVPVESADTISRQQQLFGYDHKPCNRWEQVVDVENSLHMGAKPKVAEADEAAVRKLRYVPPTWTFECDEDLVHYFYDHIGKEDENLGSVKQCVTSIDVSSSSEDPSGGASCLTDGDTETYWESDGMQGQHWIRLHMRRGTVVNKLILTVDSTDDNYMPKRVTVYGGEGDNLKKYSDVTIDDTLIGEVCVLEDMTSHLPVIEVRIEECRDEGIDVRIRGLKIKSSCERDLGLNADVFQSPNLVRYPRLEGTPPDVLYRRALVIQRFITLLDSLLPHMVPAWDYSLGTFNQIKSIKQFLLLSKRRSALITQCLKDSETSKPNFMPRLYINRRLAMEHRDNPTLDVTCKNAVLTQVYEGLKPSDKYEKTLDYRWSARYDQWWECKFIAEGIIDQGGGFRDSLADMSEELCPSSSECPLPLPFFTRTSNQGAGEARDFYVPNPSCREFNKFEWIGQLMGAALRGKDFLVLALPGLVWKQLIGEAVSWTKDFPAVDSVLVKLLEAMDHMDKETFDFKFGQELVYTTPLSDGRLVELIPGGSGVVVRYEDRVEFIRLVQKARLEENREQISAMQAGLVKVVPQAVLDLLTWQEVEKKVCGDPEITVEALKRLTRYEDLEQTDVRVQYLWEALMNFTNEDRSRFLRFVTGRSRLPAPIYIFPDKQGSETEDALPQSSTCSSTLYLPKYPSAKVCEEKLRYAAYNCVAIDTDMSPWEE", "length": 854 }, "evidence": [ { "id": "A0A8V1AC51", "url": "https://omabrowser.org/oma/group/A0A8V1AC51/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q3U487-1", "protein_name": "E3 ubiquitin-protein ligase HECTD3", "gene_name": "Hectd3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAGPGPGAALESPRQLLGRVRFLAEAARSLRAGLPLPAALAFVPREVLYKLYKDPAGPSRVLLPVWEAEGLGLRVGAVGAAPGTGSGPLRAARDSIELRRGACVRTTGEELCNGHGLWVKLTKEQLAEHLSDCSLDEGWLLVCRPAEGGARLVPIDTPDHLQRQQQLFGVDYRPVLRWEQVVDLTYSHRLGSRPQPAEAYTEAIQRLLYVPPTWTYECDEDLIHFLYDHLGKEDENLGSVKQYVESIDVSSYTEEFNVSCLTDSNADTYWESDGSQCQHWVRLTMKKGTIVKKLLLTVDTTDDNFMPKRVVVYGGEGDNLKKLSDVNIDETLIGDVCVLEDMTVHLPIIEIRIVECRDDGIDVRLRGVKIKSSRQRELGLNADLFQPASLVRYPRLEGTDPEVLYRRAVLLQRFIKILDSVLHHLVPAWDHTLGTFSEIKQVKQFLLLSRQRPSLVAQCLRDSESSKPSFMPRLYINRRLAMEHRACPSRDPACKNAVFTQVYEGLKPSDKYEKPLDYRWPMRYDQWWECKFIAEGIIDQGGGFRDSLADMSEELCPSSADTPVPLPFFVRTANQGNGTGEARDMYVPNPSCRDFAKYEWIGQLMGAALRGKEFLVLALPGFVWKQLSGEEVSWSKDFPAVDSVLVKLLEVMEGVDKETFEFKFGKELTFTTVLSDQQVVELIPGGTGIVVEYEDRSRFIQLVRKARLEESKEQVAAMQAGLLKVVPQAVLDLLTWQELEKKVCGDPEVTVDALRKLTRFEDFEPSDTRVQYFWEALNNFTNEDRSRFLRFVTGRSRLPARIYIYPDKLGYETTDALPESSTCSSTLFLPHYASAKVCEEKLRYAAYNCVAIDTDMSPWEE", "length": 861 }, "evidence": [ { "id": "A0A8V1AC51", "url": "https://omabrowser.org/oma/group/A0A8V1AC51/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5T447-1", "protein_name": "E3 ubiquitin-protein ligase HECTD3", "gene_name": "HECTD3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAGPGPGAVLESPRQLLGRVRFLAEAARSLRAGRPLPAALAFVPREVLYKLYKDPAGPSRVLLPVWEAEGLGLRVGAAGPAPGTGSGPLRAARDSIELRRGACVRTTGEELCNGHGLWVKLTKEQLAEHLGDCGLQEGWLLVCRPAEGGARLVPIDTPNHLQRQQQLFGVDYRPVLRWEQVVDLTYSHRLGSRPQPAEAYAEAVQRLLYVPPTWTYECDEDLIHFLYDHLGKEDENLGSVKQYVESIDVSSYTEEFNVSCLTDSNADTYWESDGSQCQHWVRLTMKKGTIVKKLLLTVDTTDDNFMPKRVVVYGGEGDNLKKLSDVSIDETLIGDVCVLEDMTVHLPIIEIRIVECRDDGIDVRLRGVKIKSSRQRELGLNADLFQPTSLVRYPRLEGTDPEVLYRRAVLLQRFIKILDSVLHHLVPAWDHTLGTFSEIKQVKQFLLLSRQRPGLVAQCLRDSESSKPSFMPRLYINRRLAMEHRACPSRDPACKNAVFTQVYEGLKPSDKYEKPLDYRWPMRYDQWWECKFIAEGIIDQGGGFRDSLADMSEELCPSSADTPVPLPFFVRTANQGNGTGEARDMYVPNPSCRDFAKYEWIGQLMGAALRGKEFLVLALPGFVWKQLSGEEVSWSKDFPAVDSVLVKLLEVMEGMDKETFEFKFGKELTFTTVLSDQQVVELIPGGAGIVVGYGDRSRFIQLVQKARLEESKEQVAAMQAGLLKVVPQAVLDLLTWQELEKKVCGDPEVTVDALRKLTRFEDFEPSDSRVQYFWEALNNFTNEDRSRFLRFVTGRSRLPARIYIYPDKLGYETTDALPESSTCSSTLFLPHYASAKVCEEKLRYAAYNCVAIDTDMSPWEE", "length": 861 }, "evidence": [ { "id": "A0A8V1AC51", "url": "https://omabrowser.org/oma/group/A0A8V1AC51/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "ubiquitin-protein transferase activity", "id": "GO:0004842", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004842", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AC51", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC51" } ], "pmid": "" }, { "name": "syntaxin binding", "id": "GO:0019905", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019905", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AC51", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC51" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AC51", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC51" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AC51", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC51" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 241, "end_pos": 243, "annotation": "n_glycosylation_sequon" }, { "start_pos": 561, "end_pos": 563, "annotation": "n_glycosylation_sequon" }, { "start_pos": 669, "end_pos": 671, "annotation": "n_glycosylation_sequon" }, { "start_pos": 763, "end_pos": 765, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AC51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC51" }, { "id": "PS51284", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51284" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DOC", "eco_id": "ECO_0000259", "start_pos": 201, "end_pos": 381, "start_aa": "Glu", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1AC51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC51" }, { "id": "PS50237", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50237" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "HECT", "eco_id": "ECO_0000259", "start_pos": 515, "end_pos": 841, "start_aa": "Lys", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 241, "end_pos": 243 }, { "start_pos": 561, "end_pos": 563 }, { "start_pos": 669, "end_pos": 671 }, { "start_pos": 763, "end_pos": 765 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1ACJ1-1", "uniprot_ac": "A0A8V1ACJ1", "uniprot_id": "A0A8V1ACJ1_CHICK", "mass": { "chemical_mass": 179870.0, "monoisotopic_mass": 179870.0 }, "refseq": {}, "gene_names": [ { "name": "LAMC3", "type": "recommended", "evidence": [ { "id": "A0A8V1ACJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACJ1" } ] } ], "protein_names": [ { "name": "Laminin subunit gamma 3", "type": "synonym", "evidence": [ { "id": "A0A8V1ACJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACJ1/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACJ1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LAMC3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACJ1", "locus": { "chromosome": "17", "start_pos": 6684544, "end_pos": 6661035, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027632", "url": "https://www.ensembl.org/id/ENSGALG00010027632" } ] } } ], "crossref": [ { "id": "cd00055", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00055", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000034", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000034", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000742", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000742", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002049", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002049", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008211", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008211", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050440", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050440", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056863", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056863", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A4W5", "url": "https://www.orthodb.org/?gene=A0A8V1A4W5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ACJ1", "url": "https://www.orthodb.org/?gene=A0A8V1ACJ1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10574", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10574", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10574:SF240", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10574:SF240", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00052", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00052", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00053", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00053", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00055", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00055", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24973", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24973", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1A4W5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4W5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A4W5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4W5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ACJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACJ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ACJ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACJ1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MHQLGGIAACSAPPVGLSVALGGAPAPLPAPRTERLTFPAASSRWTSEREEVPGWGPVPSHPIPSYPNPSHRAVPAGGGSVRSEPNPAMARLRELALLGVVLATAGSSPCYDPRGQPRRCMPVFENAAFGRVPLVSNTCGSPPEDYCLQMGARDASQLCQRCDAADPLLHHNASFLTDFHSQEESTWWQSQSMAFGIQHPNSVNITLHLGKSYEITYVRLKFHTSRPESFAIYKRSRADGPWVPFQFYSASCEKTYRKRQRQYLQPGENEQVAFCTDEFSDISPLSGGNVAFSTLEGRPSAYNFDGSPTLQEWVTVTDLLISLNRLNTFGDDIFKDPKVLQSYYYAISDFSVGGRCKCNGHASECALDEAGRLVCVCEHNTAGTDCQHCQPFYQDRPWARGTAEAANECLPCDCSGRSEECFYDAELFRRTGRGGHCRNCRDNTAGPRCEQCRQNHYRWEQQAACQPCHCHPAGSLRPQCDSSGTCTCKANVTGWKCERCKDGYHSLSEGGCRPCTCDPAGSVGTCDPNTGHCTCKERVEGHLCNRCQPGWFNLQPHNPIGCTSCFCYGHSAVCMAADGYEVTHIRSDFREGLEGWAAAAGDVEVPLHWADGEIGTEWDKEEPLDLRAPEKFLQNQRLSYGQPLSLLLGVEGNGTRAESGVFLLGVQLVLEGEGLQVTMSSSESQAQDGKQAVTFRLHEAEEGTEPLLSAFSFQRLLSNLTALRLRVSCGPGPGRLWLSRVQLTSARRGAGMRAGWVEECTCPPSYTGSFCESCAPGFKRDIPFGGPFVTCVPCTCNQHGDCEPLSGHCRCLHNTEGPSCERCSPGFYGNPFTGHPDDCKPCPCPGRSPCTQLPSSGEVVCTHCPPGQRGKRCELCDDGFFGDPLGHRGPVRPCVPCQCHGNVDLNAVGNCDSVSGRCLRCLHNTTGEQCHQCRPGFYGDALAPSPAGKCAPCNCNPDGSALGLEGCNPGTGQCLCLPHVLGRTCGLCQHGYYGLQAAVGCKSCECHPVGSQDSGCHAVTGQCSCQPGVTGLRCDRCEHGFFGFSARGCRACNCSPLGSASAQCHENSTCLCRPGFVGYKCDRCQANFFPDPPSSSCQPCPTCYGLVKDGVERLRVKLQEVEEWLQAPGCELRLGQPPAMGDESRGDGLSTQHLLQGAHAVLSTQVGRLSGMLSTARGHLSNAIGASGCSSRGPPKTCTLLSEIRAVLQSAQQEILHAADTLAATEIPQEIPLLPTNWSRWATEARVLAERHGDTAAQVEAAVRRALGASNTSHELLRTLLEGRVAQEAQWELEAGYEEIQQAWKELGAGMEEVAVEARRTLTAIQEANVGMAKKLQQVAAPGQQVLLVQAEALAQEVAALEQTVQAQEPAAWQSITASLSMAAGLRRDLRGTRSFLQLQDRAGSAHDLSTSAVSQGKAVLSGAESLLGSLEGMRKVLGHRKGRAALRRRMAQVRDRAMVEAQKKIKQAEKMLGNSLSVSSAARRKAGEAVHVAGESSKRAQAVLQGSKQARKHTRTLATRVSETQQELYRQQRVAEELRGSLEEAEQVGTEVSEMAKSLREARGSLMADIETLNDLLHSLGGLEPGMQTEAVLGAGRLQLERLRRRLNAPGALATQLGQLQQEAELQQDRIRVFENDLVEIRADKQNLEDILRSLPEGCSKW", "length": 1663, "header": "tr|A0A8V1ACJ1-1|A0A8V1ACJ1_CHICK Isoform 1 of Laminin subunit gamma 3 OS=Gallus gallus OX=9031 GN=LAMC3 PE=4 SV=1 CANONICAL=A0A8V1ACJ1-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A4W5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACJ1/entry#A0A8V1A4W5-1", "sequence": { "sequence": 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"MHQLGGIAACSAPPVGLSVALGGAPAPLPAPRTERLTFPAASSRWTSEREEVPGWGPVPSHPIPSYPNPSHRAVPAGGGSVRSEPNPAMARLRELALLGVVLATAGSSPCYDPRGQPRRCMPVFENAAFGRVPLVSNTCGSPPEDYCLQMGARDASQLCQRCDAADPLLHHNASFLTDFHSQEESTWWQSQSMAFGIQHPNSVNITLHLGKSYEITYVRLKFHTSRPESFAIYKRSRADGPWVPFQFYSASCEKTYRKRQRQYLQPGENEQVAFCTDEFSDISPLSGGNVAFSTLEGRPSAYNFDGSPTLQEWVTVTDLLISLNRLNTFGDDIFKDPKVLQSYYYAISDFSVGGRCKCNGHASECALDEAGRLVCVCEHNTAGTDCQHCQPFYQDRPWARGTAEAANECLPCDCSGRSEECFYDAELFRRTGRGGHCRNCRDNTAGPRCEQCRQNHYRWEQQAACQPCHCHPAGSLRPQCDSSGTCTCKANVTGWKCERCKDGYHSLSEGGCRPCTCDPAGSVGTCDPNTGHCTCKERVEGHLCNRCQPGWFNLQPHNPIGCTSCFCYGHSAVCMAADGYEVTHIRSDFREGLEGWAAAAGDVEVPLHWADGEIGTEWDKEEPLDLRAPEKFLQNQRLSYGQPLSLLLGVEGNGTRAESGVFLLGVQLVLEGEGLQVTMSSSESQAQDGKQAVTFRLHEAEEGTEPLLSAFSFQRLLSNLTALRLRVSCGPGPGRLWLSRVQLTSARRGAGMRAGWVEECTCPPSYTGSFCESCAPGFKRDIPFGGPFVTCVPCTCNQHGDCEPLSGHCRCLHNTEGPSCERCSPGFYGNPFTGHPDDCKPCPCPGRSPCTQLPSSGEVVCTHCPPGQRGKRCELCDDGFFGDPLGHRGPVRPCVPCQCHGNVDLNAVGNCDSVSGRCLRCLHNTTGEQCHQCRPGFYGDALAPSPAGKCAPCNCNPDGSALGLEGCNPGTGQCLCLPHVLGRTCGLCQHGYYGLQAAVGCKSCECHPVGSQDSGCHAVTGQCSCQPGVTGLRCDRCEHGFFGFSARGCRACNCSPLGSASAQCHENSTCLCRPGFVGYKCDRCQANFFPDPPSSSCQPCPTCYGLVKDGVERLRVKLQEVEEWLQAPGCELRLGQPPAMGDESRGDGLSTQHLLQGAHAVLSTQVGRLSGMLSTARGHLSNAIGASGCSSRGPPKTCTLLSEIRAVLQSAQQEILHAADTLAATEIPQEIPLLPTNWSRWATEARVLAERHGDTAAQVEAAVRRALGASNTSHELLRTLLEGRVAQEAQWELEAGYEEIQQAWKELGAGMEEVAVEARRTLTAIQEANVGMAKKLQQVAAPGQQVLLVQAEALAQEVAALEQTVQAQEPAAWQSITASLSMAAGLRRDLRGTRSFLQLQDRAGSAHDLSTSAVSQGKAVLSGAESLLGSLEGMRKVLGHRKGRAALRRRMAQVRDRAMVEAQKKIKQAEKMLGNSLSVSSAARRKAGEAVHVAGESSKRAQAVLQGSKQARKHTRTLATRVSETQQELYRQQRVAEELRGSLEEAEQVGTEVSEMAKSLREARGSLMADIETLNDLLHSLGGLEPGMQTEAVLGAGRLQLERLRRRLNAPGALATQLGQLQQEAELQQDRIRVFENDLVEIRADKQNLEDILRSLPEGCSKW", "length": 1663, "header": "tr|A0A8V1ACJ1-1|A0A8V1ACJ1_CHICK Isoform 1 of Laminin subunit gamma 3 OS=Gallus gallus OX=9031 GN=LAMC3 PE=4 SV=1 CANONICAL=A0A8V1ACJ1-1" }, "locus": { "chromosome": "17", "start_pos": 6683663, "end_pos": 6669313, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066963.1", "url": "https://www.ensembl.org/id/ENSGALT00010066963.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040953.1", "url": "https://www.ensembl.org/id/ENSGALP00010040953.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACJ1" } ], "pmid": "" }, { "name": "animal organ morphogenesis", "id": "GO:0009887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009887", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACJ1" } ], "pmid": "" }, { "name": "axon guidance", "id": "GO:0007411", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007411", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACJ1" } ], "pmid": "" }, { "name": "tissue development", "id": "GO:0009888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009888", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACJ1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "basement membrane", "id": "GO:0005604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005604", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACJ1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1053, "end_pos": 1055, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1067, "end_pos": 1069, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1237, "end_pos": 1239, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1271, "end_pos": 1273, "annotation": "n_glycosylation_sequon" }, { "start_pos": 172, "end_pos": 174, "annotation": "n_glycosylation_sequon" }, { "start_pos": 204, "end_pos": 206, "annotation": "n_glycosylation_sequon" }, { "start_pos": 491, "end_pos": 493, "annotation": "n_glycosylation_sequon" }, { "start_pos": 653, "end_pos": 655, "annotation": "n_glycosylation_sequon" }, { "start_pos": 719, "end_pos": 721, "annotation": "n_glycosylation_sequon" }, { "start_pos": 924, "end_pos": 926, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1ACJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACJ1" }, { "id": "PS50027", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50027" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Laminin EGF-like", "eco_id": "ECO_0000259", "start_pos": 468, "end_pos": 514, "start_aa": "Cys", "end_aa": "Pro", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1ACJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACJ1" }, { "id": "PS51115", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51115" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Laminin IV type A", "eco_id": "ECO_0000259", "start_pos": 591, "end_pos": 759, "start_aa": "Glu", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1ACJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACJ1" }, { "id": "PS51117", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51117" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Laminin N-terminal", "eco_id": "ECO_0000259", "start_pos": 116, "end_pos": 355, "start_aa": "Gln", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1053, "end_pos": 1055 }, { "start_pos": 1067, "end_pos": 1069 }, { "start_pos": 1237, "end_pos": 1239 }, { "start_pos": 1271, "end_pos": 1273 }, { "start_pos": 172, "end_pos": 174 }, { "start_pos": 204, "end_pos": 206 }, { "start_pos": 491, "end_pos": 493 }, { "start_pos": 653, "end_pos": 655 }, { "start_pos": 719, "end_pos": 721 }, { "start_pos": 924, "end_pos": 926 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1ACN9-1", "uniprot_ac": "A0A8V1ACN9", "uniprot_id": "A0A8V1ACN9_CHICK", "mass": { "chemical_mass": 48168.0, "monoisotopic_mass": 48168.0 }, "refseq": { "ac": "NP_001300613", "name": "triggering receptor expressed on myeloid cells B1 precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001300613" }, "gene_names": [ { "name": "TREMB1", "type": "recommended", "evidence": [ { "id": "A0A8V1ACN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACN9" } ] }, { "name": "TREM-B1", "type": "synonym", "evidence": [ { "id": "NP_001300613", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001300613" } ] }, { "name": "TREMB1", "type": "synonym", "evidence": [ { "id": "NP_001300613", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001300613" } ] } ], "protein_names": [ { "name": "Triggering receptor expressed on myeloid cells B1", "type": "synonym", "evidence": [ { "id": "A0A8V1ACN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACN9/entry#names_and_taxonomy" } ] }, { "name": "triggering receptor expressed on myeloid cells B1 precursor", "type": "synonym", "evidence": [ { "id": "NP_001300613", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001300613" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AM076722.1, ERR2365563.122442.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992393, SAMEA103992415 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from HAEK01061997.1, HAEK01057698.1, AM076722.1, JAENSK010000356.1, HAEK01019955.1, BU472343.1, CF255953.1 and HAEK01169125.1. On Nov 23, 2021 this sequence version replaced NP_001300613.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001300613", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001300613" } ] }, { "annotation": "TREM-B1, an Inhibitory Ig-Like Receptor Expressed on Chicken Thrombocytes Publication Status: Online-Only", "evidence": [ { "database": "RefSeq", "id": "NP_001300613", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001300613" }, { "database": "PubMed", "id": "26967520", "url": "https://glygen.org/publication/PubMed/26967520" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACN9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACN9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TREMB1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACN9", "locus": { "chromosome": "26", "start_pos": 4781431, "end_pos": 4787912, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027664", "url": "https://www.ensembl.org/id/ENSGALG00010027664" } ] } } ], "crossref": [ { "id": "A0A8V1ACN9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1ACN9", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd05716", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05716", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "768535", "url": "https://www.ncbi.nlm.nih.gov/gene/768535", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013106", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013106", "database": "InterPro", "categories": [ "Protein Classification" ] }, 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"26", "start_pos": 4787255, "end_pos": 4782275, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067071.1", "url": "https://www.ensembl.org/id/ENSGALT00010067071.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041001.1", "url": "https://www.ensembl.org/id/ENSGALP00010041001.1" } ] } }, { "isoform_ac": "A0A8V1ACN9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACN9/entry#A0A8V1ACN9-1", "sequence": { "sequence": "MPYTTFYFRMGSFPALLLLLVLPGSHMAGEDTQVFLQVQGESFRANCSYDMHKHSHEKKFWCKEQPERYCTDLSLSFPSEERIGPNRALYHPVELRDSGGGWFSVIMTALRKEDSGTYQCGVWVEMKQVLLQRIQMVVSPKETVTVFAKKGKSLFLHCSYSMTVNIRELQHFIWCKMVSRIRCQPIIRGNADQSIVKAERTEMMNDFSWKMIRVWLKKLQLNDSGEYHLESRFQGRNKLLKRIMLKVLASAGSSKTERTEQKQSDFSDLTEKRRRGGEKWNMDASPIDDSRKDQRTPYAVMVLISLLATAVLIATVTLITSCIRKKRAGKEMDFDRHPAFRKGVLQEGREKASRMPDGDHNESTIYAAIRHQPQPKPEDVMYVNIQPSPKVFLLQEPPGSSHPSGPVEYATLIFKDTTL", "length": 419, "header": "tr|A0A8V1ACN9-1|A0A8V1ACN9_CHICK Isoform 1 of Triggering receptor expressed on myeloid cells B1 OS=Gallus gallus OX=9031 GN=TREMB1 PE=4 SV=1 CANONICAL=A0A8V1ACN9-1" }, "locus": { "chromosome": "26", "start_pos": 4787255, "end_pos": 4782275, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067076.1", "url": "https://www.ensembl.org/id/ENSGALT00010067076.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041003.1", "url": "https://www.ensembl.org/id/ENSGALP00010041003.1" } ] } }, { "isoform_ac": "A0A8V1AF99-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACN9/entry#A0A8V1AF99-1", "sequence": { "sequence": "MDVFLCKPAETDNSSHCPRGSHMAGEDTQVFLQVQGESFRANCSYDMHKHSHEKKFWCKEQPERYCTDLSLSFPSEERIGPNRALYHPVELRDSGGGWFSVIMTALRKEDSGTYQCGVWVEMKQVLLQRIQMVVSPKETVTVFAKKGKSLFLHCSYSMTVNIRELQHFIWCKMVSRIRCQPIIRGNADQSIVKAERTEMMNDFSWKMIRVWLKKLQLNDSGEYHLESRFQGRNKLLKRIMLKVLASAGSSKTERTEQKQSDFSDLTEKRRRGGEKWNMDASPIDDSRKDQRTPYAVMVLISLLATAVLIATVTLITSCIRKKRAGKEMDFDRHPAFRKGVLQEGREKASRMPDGDHNESTIYAAIRHQPQPKPEDVMYVNIQPSPKVFLLQEPPGSSHPSGPVEYATLIFKDTTL", "length": 415, "header": "tr|A0A8V1AF99-1|A0A8V1AF99_CHICK Computationally mapped isoform of Triggering receptor expressed on myeloid cells B1 OS=Gallus gallus OX=9031 GN=TREMB1 PE=4 SV=1 CANONICAL=A0A8V1ACN9-1" }, "locus": { "chromosome": "26", "start_pos": 4786799, "end_pos": 4782275, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067067.1", "url": "https://www.ensembl.org/id/ENSGALT00010067067.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040997.1", "url": "https://www.ensembl.org/id/ENSGALP00010040997.1" } ] } }, { "isoform_ac": "A0A8V1AH88-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACN9/entry#A0A8V1AH88-1", "sequence": { "sequence": "MPYTTFYFRMGSFPALLLLLVLPGSHMAGEDTQVFLQVQGESFRANCSYDMHKHSHEKKFWCKEQPERYCTDLSLSFPSEERIGPNRALYHPVELRDSGGGWFSVIMTALRKEDSGTYQCGVWVEMKQVLLQRIQMVVSPKETVTVFAKKGKSLFLHCSYSMTVNIRELQHFIWCKMVSRIRCQPIIRGNADQSIVKAERTEMMNDFSWKMIRVWLKKLQLNDSGEYHLESRFQGRNKLLKRIMLKVLASAGSSKTERTEQKQSDFSDLTEKRRRGGEKWNMDASPIDDSRKDQRTPYAVMVLISLLATAVLIATVTLITSCIRKKRAGKALLSFPCPCSLEGREKASRMPDGDHNESTIYAAIRHQPQPKPEDVMYVNIQPSPKVFLLQEPPGSSHPSGPVEYATLIFKDTTL", "length": 414, "header": "tr|A0A8V1AH88-1|A0A8V1ACN9_CHICK Computationally mapped isoform of Triggering receptor expressed on myeloid cells B1 OS=Gallus gallus OX=9031 GN=TREMB1 PE=4 SV=1 CANONICAL=A0A8V1ACN9-1" }, "locus": { "chromosome": "26", "start_pos": 4787255, "end_pos": 4782275, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067055.1", "url": "https://www.ensembl.org/id/ENSGALT00010067055.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040990.1", "url": "https://www.ensembl.org/id/ENSGALP00010040990.1" } ] } } ], 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4795965, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067134.1", "url": "https://www.ensembl.org/id/ENSGALT00010067134.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041038.1", "url": "https://www.ensembl.org/id/ENSGALP00010041038.1" } ] } }, { "isoform_ac": "A0A8V1AHB9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACS3/entry#A0A8V1AHB9-1", "sequence": { "sequence": "FPYCQTLFLLWSCLPAQTAEAEISQQEGSTFSIQCPYTTQPENEQLKAWCRMRNARCQLVAWTLASMQYIYSDRARQGHLTIQDDNRTVSITMSDLQAEDSGIYSCVYSSNYVPLKTISLNVYKVPAATTLSVTTSSSQKNSSGNSTQPRNTITISVVLCILLILAFTITTALCIRQRKKLKTGGNRQAEDIYDKPESPAQLESTENMGRTTDDSRDLNYITLDFKPRLSSDEPLYCNVEPSQAPRKPEDENVEYAIITHKQLPKNDKG", "length": 269, "header": "tr|A0A8V1AHB9-1|A0A8V1ACS3_CHICK Computationally mapped isoform of Triggering receptor expressed on myeloid cells B2 OS=Gallus gallus OX=9031 GN=TREMB2 PE=4 SV=1 CANONICAL=A0A8V1ACS3-1" }, "locus": { "chromosome": "26", "start_pos": 4800236, "end_pos": 4795810, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067126.1", "url": "https://www.ensembl.org/id/ENSGALT00010067126.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041030.1", "url": "https://www.ensembl.org/id/ENSGALP00010041030.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:768582", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:768582", "resource": "KEGG Pathway" }, { "id": "R-GGA-198933", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-198933", "resource": "Reactome", "description": "Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACS3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACS3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "signaling receptor activity", "id": "GO:0038023", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038023", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACS3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACS3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 181, "end_pos": 183, "annotation": "n_glycosylation_sequon" }, { "start_pos": 309, "end_pos": 311, "annotation": "n_glycosylation_sequon" }, { "start_pos": 402, "end_pos": 404, "annotation": "n_glycosylation_sequon" }, { "start_pos": 473, "end_pos": 475, "annotation": "n_glycosylation_sequon" }, { "start_pos": 477, "end_pos": 479, "annotation": "n_glycosylation_sequon" }, { "start_pos": 88, "end_pos": 90, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AD26-1", "uniprot_ac": "A0A8V1AD26", "uniprot_id": "A0A8V1AD26_CHICK", "mass": { "chemical_mass": 74997.0, "monoisotopic_mass": 74997.0 }, "refseq": {}, "gene_names": [ { "name": "OLFML2A", "type": "recommended", "evidence": [ { "id": "A0A8V1AD26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD26" } ] } ], "protein_names": [ { "name": "Olfactomedin like 2A", "type": "synonym", "evidence": [ { "id": "A0A8V1AD26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD26/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AD26", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD26" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "OLFML2A", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD26", "locus": { "chromosome": "17", "start_pos": 10128239, "end_pos": 10122168, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027731", "url": "https://www.ensembl.org/id/ENSGALG00010027731" } ] } } ], "crossref": [ { "id": "A0A8V1AD26", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AD26", "database": "AlphaFoldDB", "categories": [] }, { "id": "417098", "url": "https://www.ncbi.nlm.nih.gov/gene/417098", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003112", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003112", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050605", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050605", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "FRNEHAY", "url": "https://omabrowser.org/oma/group/FRNEHAY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A5E6", "url": "https://www.orthodb.org/?gene=A0A8V1A5E6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AD26", "url": "https://www.orthodb.org/?gene=A0A8V1AD26", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23192", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23192", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23192:SF29", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23192:SF29", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02191", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02191", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1A5E6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5E6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A5E6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5E6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AD26", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD26", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AD26-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD26-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGEPIHRAKLTPGQLQLSVNNRPCVGCELHGPRGHAAAHEGRAARLGLASSWEMAAGVDTLSLGTWCSAAGALGEDQVRMTSEGSDCRCKCILRPLSKDACSRVRNGSARVEDFYTVETVSSGVDCKCSCTAPPSSLNPCENEWKMEKLKKQAPELFKLQSMVDLLEGTLYSMDLMKVHSYISKVVAQMNTLEETIKTNLSRDNDIMKESVLHLADQMKRYENYSDIMISIKKEISNLGYQLLQKDAAASPDSKAQDTAGGRGKEAVRFPAVRKALPARTPKEKPLKPEKPKKENAKRGGPQPTAKPKVPAQHQTVVRGITYYKAGQVEEVQRAASSRESPARVVAVPERQEERGLADTPSQPGTRAEPPLPHTTAAPSTAPAPRTAAHSPPGTALGDGAVSTGGPEAPNRVKEMECEGTIRSVDPPMEHHSYGRNEGAWMKDPAAKDDRIYVTNYYYGNSLVEFRSLENFKQGRWSNLYKLPYNWIGTGHVVYRGAFYYNRAFTKNIIKYDLKERYVAGWALLHDVVYEDTTPWKWRGHSDIDFAVDESGLWVIYPSADDDYAQQEVIVLSRLDPGDLSVRRETTWRTGLKRNAYGNCFIICGILYAVDTSSQKEGQISYAFDTHTDTEAELRLPFLNEYAFTTQVDYNPKEKVLYAWDNGHQMTYRLHFVV", "length": 673, "header": "tr|A0A8V1AD26-1|A0A8V1AD26_CHICK Isoform 1 of Olfactomedin like 2A OS=Gallus gallus OX=9031 GN=OLFML2A PE=4 SV=1 CANONICAL=A0A8V1AD26-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A5E6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD26/entry#A0A8V1A5E6-1", "sequence": { "sequence": "MTSEGSDCRCKCILRPLSKDACSRVRNGSARVEDFYTVETVSSGVDCKCSCTAPPSSLNPCENEWKMEKLKKQAPELFKLQSMVDLLEGTLYSMDLMKVHSYISKVVAQMNTLEETIKTNLSRDNDIMKESVLHLADQMKRYENYSDIMISIKKEISNLGYQLLQKDAAASPDSKAQDTAGGRGKEAVRFPAVRKALPARTPKEKPLKPEKPKKENAKRGGPQPTAKPKVPAQHQTVVRGITYYKAGQVEEVQRAASSRESPARVVAVPERQEERGLADTPSQPGTRAEPPLPHTTAAPSTAPAPRTAAHSPPGTALGDGAVSTGGPEAPNRVKEMECEGTIRSVDPPMEHHSYGRNEGAWMKDPAAKDDRIYVTNYYYGNSLVEFRSLENFKQGRWSNLYKLPYNWIGTGHVVYRGAFYYNRAFTKNIIKYDLKERYVAGWALLHDVVYEDTTPWKWRGHSDIDFAVDESGLWVIYPSADDDYAQQEVIVLSRLDPGDLSVRRETTWRTGLKRNAYGNCFIICGILYAVDTSSQKEGQISYAFDTHTDTEAELRLPFLNEYAFTTQVDYNPKEKVLYAWDNGHQMTYRLHFVV", "length": 594, "header": "tr|A0A8V1A5E6-1|A0A8V1AD26_CHICK Computationally mapped isoform of Olfactomedin like 2A OS=Gallus gallus OX=9031 GN=OLFML2A PE=4 SV=1 CANONICAL=A0A8V1AD26-1" }, "locus": { "chromosome": "17", "start_pos": 10127593, "end_pos": 10125185, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067225.1", "url": "https://www.ensembl.org/id/ENSGALT00010067225.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041129.1", "url": "https://www.ensembl.org/id/ENSGALP00010041129.1" } ] } }, { "isoform_ac": "A0A8V1AD26-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD26/entry#A0A8V1AD26-1", "sequence": { "sequence": "MGEPIHRAKLTPGQLQLSVNNRPCVGCELHGPRGHAAAHEGRAARLGLASSWEMAAGVDTLSLGTWCSAAGALGEDQVRMTSEGSDCRCKCILRPLSKDACSRVRNGSARVEDFYTVETVSSGVDCKCSCTAPPSSLNPCENEWKMEKLKKQAPELFKLQSMVDLLEGTLYSMDLMKVHSYISKVVAQMNTLEETIKTNLSRDNDIMKESVLHLADQMKRYENYSDIMISIKKEISNLGYQLLQKDAAASPDSKAQDTAGGRGKEAVRFPAVRKALPARTPKEKPLKPEKPKKENAKRGGPQPTAKPKVPAQHQTVVRGITYYKAGQVEEVQRAASSRESPARVVAVPERQEERGLADTPSQPGTRAEPPLPHTTAAPSTAPAPRTAAHSPPGTALGDGAVSTGGPEAPNRVKEMECEGTIRSVDPPMEHHSYGRNEGAWMKDPAAKDDRIYVTNYYYGNSLVEFRSLENFKQGRWSNLYKLPYNWIGTGHVVYRGAFYYNRAFTKNIIKYDLKERYVAGWALLHDVVYEDTTPWKWRGHSDIDFAVDESGLWVIYPSADDDYAQQEVIVLSRLDPGDLSVRRETTWRTGLKRNAYGNCFIICGILYAVDTSSQKEGQISYAFDTHTDTEAELRLPFLNEYAFTTQVDYNPKEKVLYAWDNGHQMTYRLHFVV", "length": 673, "header": "tr|A0A8V1AD26-1|A0A8V1AD26_CHICK Isoform 1 of Olfactomedin like 2A OS=Gallus gallus OX=9031 GN=OLFML2A PE=4 SV=1 CANONICAL=A0A8V1AD26-1" }, "locus": { "chromosome": "17", "start_pos": 10127593, "end_pos": 10124787, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067224.1", "url": "https://www.ensembl.org/id/ENSGALT00010067224.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041128.1", "url": "https://www.ensembl.org/id/ENSGALP00010041128.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "D3ZMR0-1", "protein_name": "Olfactomedin-like 2A", "gene_name": "Olfml2a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEAAAVLPRCLQLRLLLVLLLLVLLRAGPVWPDSKVFSDLDQVRMTSEGSDCRCKCIMRPLSKDACSRVRSGRARVEDFYTVETLSSGADCRCSCTAPPSSLNPCENEWKMEKLKKQAPELLKLQSMVDLLEGALYSMDLMKVHAYIQKVASQMNTLEESIKTNLSLENEVVKDSVRHLSEQLKSYENQSAIMMSIKKELSNLGLQLLQRDAAAIPASAPASSSDNKAQDTAGGQGKELNKYGGIQKSFSDKSLAKPPKEKLLKVEKLKKETIKGRIPPHPTARPRALAQQQAVIRGFTYYKAGRQEARQEAPKAAADNTLKGASWLEKLPPKTEAKLPEPNSAKHDDIRLQASEGANLAPDFSTTTTTTTTTTTTTTTTTPTPITTPWPTEPPLHPEVPSQGREDSCEGTLRAVDPPVKHHSYGRHEGAWMKDPAAPDDRIYVTNYYYGNSLVEFRNLENFKQGRWSNMYKLPYNWIGTGHVVYQGAFYYNRAFTKNIIKYDLRQRFVASWALLPDVVYEDTTPWKWRGHSDIDFAVDESGLWVIYPAMDEHGETQHEVIVVSRLDPADLSVHRETTWKTRLRRNSYGNCFLVCGILYTVDTYNQHEGQVAYAFDTHTGTDAYPQLPFLNEYSYTTQVDYNPKERVLYAWDNGHQLTYTLHFVV", "length": 665 }, "evidence": [ { "id": "A0A8V1AD26", "url": "https://omabrowser.org/oma/group/A0A8V1AD26/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8BHP7-1", "protein_name": "Olfactomedin-like protein 2A", "gene_name": "Olfml2a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEAAAVLPRYLQLRLLLVLLLLVLLRAGPVWPDSKVFSDLDQVRMTSEGSDCRCKCIMRPLSKDACSRVRSGRARVEDFYTVETVSSGADCRCSCTAPPSSLNPCENEWKMEKLKKQAPELLKLQSMVDLLEGALYSMDLMKVHAYIQKVASQMNTLEESIKANLSLENKVVKDSVHHLSEQLKSYENQSAIMMSIKKELSSLGLQLLQRDAAAVPATAPASSPDSKAQDTAGGQGRDLNKYGSIQKSFSDKGLAKPPKEKLLKVEKLRKESIKGRIPQPTARPRALAQQQAVIRGFTYYKAGRQEARQEARQEAPKAAADSTLKGTSWLEKLPPKIEAKLPEPNSAKHDDVRLQASEGGNLTPDITTTTTSTSSSTTTTTGTTSTTSTTSTTSTTTPSPITTPWPTEPPLHPEVPSQGREDSCEGTLRAVDPPVKHHSYGRHEGAWMKDPAALDDRIYVTNYYYGNSLVEFRNLENFKQGRWSNMYKLPYNWIGTGHVVYQGAFYYNRAFTKNIIKYDLRQRFVASWALLPDVVYEDTTPWKWRGHSDIDFAVDESGLWVIYPAVDEHDETQHEVIVLSRLDPADLSVHRETTWKTRLRRNSYGNCFLVCGILYTVDTYNQHEGQVAYAFDTHTGTDAHPQLPFLNEYSYTTQVDYNPKERVLYAWDNGHQLTYTLHFVV", "length": 681 }, "evidence": [ { "id": "A0A8V1AD26", "url": "https://omabrowser.org/oma/group/A0A8V1AD26/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AD26", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD26" } ], "pmid": "" }, { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AD26", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD26" } ], "pmid": "" }, { "name": "extracellular matrix", "id": "GO:0031012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031012", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AD26", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD26" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AD26", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD26" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AD26", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD26" } ], "pmid": "" }, { "name": "extracellular matrix binding", "id": "GO:0050840", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050840", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AD26", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD26" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 106, "end_pos": 108, "annotation": "n_glycosylation_sequon" }, { "start_pos": 199, "end_pos": 201, "annotation": "n_glycosylation_sequon" }, { "start_pos": 223, "end_pos": 225, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AD26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD26" }, { "id": "PS51132", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51132" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Olfactomedin-like", "eco_id": "ECO_0000259", "start_pos": 416, "end_pos": 673, "start_aa": "Glu", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 106, "end_pos": 108 }, { "start_pos": 199, "end_pos": 201 }, { "start_pos": 223, "end_pos": 225 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1ADN3-1", "uniprot_ac": "A0A8V1ADN3", "uniprot_id": "A0A8V1ADN3_CHICK", "mass": { "chemical_mass": 49434.0, "monoisotopic_mass": 49434.0 }, "refseq": { "ac": "XP_024999195", "name": "interleukin-6 receptor subunit alpha isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024999195" }, "gene_names": [ { "name": "IL6R", "type": "recommended", "evidence": [ { "id": "A0A8V1ADN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADN3" } ] }, { "name": "IL6RA", "type": "synonym", "evidence": [ { "id": "XP_024999195", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024999195" } ] }, { "name": "IL6R", "type": "synonym", "evidence": [ { "id": "XP_024999195", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024999195" } ] } ], "protein_names": [ { "name": "Interleukin 6 receptor", "type": "synonym", "evidence": [ { "id": "A0A8V1ADN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADN3/entry#names_and_taxonomy" } ] }, { "name": "interleukin-6 receptor subunit alpha isoform X1", "type": "synonym", "evidence": [ { "id": "XP_024999195", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024999195" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052556.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_024999195.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_024999195", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024999195" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADN3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADN3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "IL6R", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADN3", "locus": { "chromosome": "25", "start_pos": 1942224, "end_pos": 1936725, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027886", "url": "https://www.ensembl.org/id/ENSGALG00010027886" } ] } } ], "crossref": [ { "id": "A0A8V1ADN3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1ADN3", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00063", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00063", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "693252", "url": "https://www.ncbi.nlm.nih.gov/gene/693252", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003530", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003530", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015321", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015321", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050379", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050379", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IIHDAWR", "url": "https://omabrowser.org/oma/group/IIHDAWR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A600", "url": "https://www.orthodb.org/?gene=A0A8V1A600", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ADN3", "url": "https://www.orthodb.org/?gene=A0A8V1ADN3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AG75", "url": "https://www.orthodb.org/?gene=A0A8V1AG75", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23036", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23036", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23036:SF98", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23036:SF98", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23037", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23037", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23037:SF35", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23037:SF35", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF09240", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09240", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-1059683", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1059683", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9958825", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9958825", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_024999195", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024999195", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1A600", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A600", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A600-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A600-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ADN3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADN3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ADN3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADN3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AG75", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG75", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AG75-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG75-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MARPPGLLRAALLLLTAASSAPRRRCGPVALPQDTVLGRPGANVTLLCREREPPNGTVLWSGRRRALGGGNALLLGGLRPEDAGRYSCHLGGHTLRTVRLLVEAPHCPTEPPEPPHVSCSRRSHDKDVLCEWRPRASPAPGTRAVLWMKRRFTMENATEQRCHFYSAAQKFVCRVKVPPGTDDTKALVVSVCVSSRAGSAAAEDRIFTLNGILKPDPPLNVTVEAVERSPQRLCVRWSYPPSWDPRFYWLRFQVRYRPEPAPNFTQVDQVTRTWLDIRDAWRGMRHVVQVRAQEEFGHGAWSEWSREAVGTPWTEPRDVTEMGLYSSQFPAEDDPYGYGATLPPELFGDDTADDAGGAVLEAAVRSPTSPYALLVAGGSLLLAIILCFAIGMRYKQRARAQRGAKLEGGGQHPMVPLCPPGSPLSATPLLSPAAPPGPLHVTNLDYFLSGK", "length": 451, "header": "tr|A0A8V1ADN3-1|A0A8V1ADN3_CHICK Isoform 1 of Interleukin 6 receptor OS=Gallus gallus OX=9031 GN=IL6R PE=3 SV=1 CANONICAL=A0A8V1ADN3-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A600-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADN3/entry#A0A8V1A600-1", "sequence": { "sequence": "MARPPGLLRAALLLLTAASSAPRRRCGPVALPQDTVLGRPGANVTLLCREREPPNGTVLWSGRRRALGGGNALLLGGLRPEDAGRYSCHLGGHTLRTVRLLVEEPPEPPHVSCSRRSHDKDVLCEWRPRASPAPGTRAVLWMKRRFTMENATEQRCHFYSAAQKFVCRVKVPPGTDDTKALVVSVCVSSRAGSAAAEDRIFTLNGILKPDPPLNVTVEAVERSPQRLCVRWSYPPSWDPRFYWLRFQVRYRPEPAPNFTQVDQVTRTWLDIRDAWRGMRHVVQFPAEDDPYGYGATLPPELFGDDTADDAGGAVLEAAVRSPTSPYALLVAGGSLLLAIILCFAIGMRYKQRARAQRGAKLEGGGQHPMVPLCPPGSPLSATPLLSPAAPPGPLHVTNLDYFLSGK", "length": 406, "header": "tr|A0A8V1A600-1|A0A8V1ADN3_CHICK Computationally mapped isoform of Interleukin 6 receptor OS=Gallus gallus OX=9031 GN=IL6R PE=3 SV=1 CANONICAL=A0A8V1ADN3-1" }, "locus": { "chromosome": "25", "start_pos": 1941845, "end_pos": 1936831, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067590.1", "url": "https://www.ensembl.org/id/ENSGALT00010067590.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041333.1", "url": "https://www.ensembl.org/id/ENSGALP00010041333.1" } ] } }, { "isoform_ac": "A0A8V1ADN3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADN3/entry#A0A8V1ADN3-1", "sequence": { "sequence": "MARPPGLLRAALLLLTAASSAPRRRCGPVALPQDTVLGRPGANVTLLCREREPPNGTVLWSGRRRALGGGNALLLGGLRPEDAGRYSCHLGGHTLRTVRLLVEAPHCPTEPPEPPHVSCSRRSHDKDVLCEWRPRASPAPGTRAVLWMKRRFTMENATEQRCHFYSAAQKFVCRVKVPPGTDDTKALVVSVCVSSRAGSAAAEDRIFTLNGILKPDPPLNVTVEAVERSPQRLCVRWSYPPSWDPRFYWLRFQVRYRPEPAPNFTQVDQVTRTWLDIRDAWRGMRHVVQVRAQEEFGHGAWSEWSREAVGTPWTEPRDVTEMGLYSSQFPAEDDPYGYGATLPPELFGDDTADDAGGAVLEAAVRSPTSPYALLVAGGSLLLAIILCFAIGMRYKQRARAQRGAKLEGGGQHPMVPLCPPGSPLSATPLLSPAAPPGPLHVTNLDYFLSGK", "length": 451, "header": "tr|A0A8V1ADN3-1|A0A8V1ADN3_CHICK Isoform 1 of Interleukin 6 receptor OS=Gallus gallus OX=9031 GN=IL6R PE=3 SV=1 CANONICAL=A0A8V1ADN3-1" }, "locus": { "chromosome": "25", "start_pos": 1941845, "end_pos": 1936831, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067589.1", "url": "https://www.ensembl.org/id/ENSGALT00010067589.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041332.1", "url": "https://www.ensembl.org/id/ENSGALP00010041332.1" } ] } }, { "isoform_ac": "A0A8V1AG75-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADN3/entry#A0A8V1AG75-1", "sequence": { "sequence": "QILTRSALPQDTVLGRPGANVTLLCREREPPNGTVLWSGRRRALGGGNALLLGGLRPEDAGRYSCHLGGHTLRTVRLLVEEPPEPPHVSCSRRSHDKDVLCEWRPRASPAPGTRAVLWMKRRFTMENATEQRCHFYSAAQKFVCRVKVPPGTDDTKALVVSVCVSSRAGSAAAEDRIFTLNGILKPDPPLNVTVEAVERSPQRLCVRWSYPPSWDPRFYWLRFQVRYRPEPAPNFTQVDQVTRTWLDIRDAWRGMRHVVQVRAQEEFGHGAWSEWSREAVGTPWTEPRDVTEMGLYSSQFPAEDDPYGYGATLPPELFGDDTADDAGGAVLEAAVRSPTSPYALLVAGGSLLLAIILCFAIGMRYKQRARAQRGAKLEGGGQHPMVPLCPPGSPLSATPLLSPAAPPGPLHVTNLDYFLSGK", "length": 422, "header": "tr|A0A8V1AG75-1|A0A8V1ADN3_CHICK Computationally mapped isoform of Interleukin 6 receptor OS=Gallus gallus OX=9031 GN=IL6R PE=3 SV=1 CANONICAL=A0A8V1ADN3-1" }, "locus": { "chromosome": "25", "start_pos": 1941845, "end_pos": 1937901, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067588.1", "url": "https://www.ensembl.org/id/ENSGALT00010067588.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041331.1", "url": "https://www.ensembl.org/id/ENSGALP00010041331.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-1059683", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1059683", "resource": "Reactome", "description": "Interleukin-6 signaling" }, { "id": "R-GGA-9958825", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9958825", "resource": "Reactome", "description": "Activation of STAT3 by cadherin engagement" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A480V8W8-1", "protein_name": "Interleukin-6 receptor subunit alpha", "gene_name": "IL6R", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLAVRCALLTALLAAPGMALAPRGCSKLEVAQDVLTSLPGASVTLTCPGGEPGDNATIHWVLRNQVTGSPDGRPAGVGRRLLLKSVQLSDSGNYSCYQDGVPAGSVRLLVDAPPEEPQLSCFRKSPLSNVGCEWRPRSPPSPTTKAVLLVRKFQNSPVEDFQEPCQYSLEAQRFFCQLAVPEGDNSFHIVTLCVANSAGSQSSTPQTFEGYGILQPDPPVNITVSAVDRNPRWLSVTWQDPPSWNSYFYRLQFELRYRAERSKTFTTWMVKELQHHCIIHDAWSGMRHVVQLRAQEEFGHGLWSEWSQEVTGIPWTESRSSPAETELPLSTQAPTTNEDDEDISSKESANATSLPVQDSASVPLPTFLVAGGSLAFGTLLCIGIILRFKKTGQLQALKEGKTNMHPPYSLGQLVPERPKSTPVLVPLISPPVSPNSLGDNTSRNSRPEARGPQSPYDVSNRDYFFPR", "length": 467 }, "evidence": [ { "id": "A0A8V1ADN3", "url": "https://omabrowser.org/oma/group/A0A8V1ADN3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "E1BJQ3-1", "protein_name": "Interleukin-6 receptor subunit alpha", "gene_name": "IL6R", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MLAVRCALLTALLAASGTALVLKGCPALEVASDVLTSVPGANVTLTCPGGGPEDNATVHWVLRDQMTGSHHGRPAGVGRRLLLQSVQLSDSGNYSCYREDHPAGSVRLVVDVPPEKPQISCIQKSPLSRVNCEWSPRSPPSLTTKAVLLVKKFPKQVFQEPCQYSPESQRFSCQLAVPEGDSSFYVLSLCVANSAGNKSSNPLGFDGYKLLQPDPPVNITVSAVDRNPRWLSVTWQDPPSWNSYYYRLQFELRYRTERSETFTTLMLKDPQYHCIINDAWSGMRHVVQLRAQEEFGNGLWSEWSPEVTGTPWTESRSSTTTKLPTSTQAPTTTEDNENIFSKDSAKTTSLPVQDSTSVPLPAFLVAGGSLAFGTLLCIGIILRFKKTGKLQALKEGKTSAHPSYSLGQLVPERPKPTPALVPLISPPVSPSSLESDNTSRNSRPDAKGPGSPYDVSNRDYFFPR", "length": 464 }, "evidence": [ { "id": "A0A8V1ADN3", "url": "https://omabrowser.org/oma/group/A0A8V1ADN3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P22272-1", "protein_name": "Interleukin-6 receptor subunit alpha", "gene_name": "Il6ra", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLTVGCTLLVALLAAPAVALVLGSCRALEVANGTVTSLPGATVTLICPGKEAAGNVTIHWVYSGSQNREWTTTGNTLVLRDVQLSDTGDYLCSLNDHLVGTVPLLVDVPPEEPKLSCFRKNPLVNAICEWRPSSTPSPTTKAVLFAKKINTTNGKSDFQVPCQYSQQLKSFSCQVEILEGDKVYHIVSLCVANSVGSKSSHNEAFHSLKMVQPDPPANLVVSAIPGRPRWLKVSWQHPETWDPSYYLLQFQLRYRPVWSKEFTVLLLPVAQYQCVIHDALRGVKHVVQVRGKEELDLGQWSEWSPEVTGTPWIAEPRTTPAGILWNPTQVSVEDSANHEDQYESSTEATSVLAPVQESSSMSLPTFLVAGGSLAFGLLLCVFIILRLKQKWKSEAEKESKTTSPPPPPYSLGPLKPTFLLVPLLTPHSSGSDNTVNHSCLGVRDAQSPYDNSNRDYLFPR", "length": 460 }, "evidence": [ { "id": "A0A8V1ADN3", "url": "https://omabrowser.org/oma/group/A0A8V1ADN3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P22273-1", "protein_name": "Interleukin-6 receptor subunit alpha", "gene_name": "Il6r", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLAVGCTLLVALLAAPAVALVLGSCRALEVANGTVTSLPGATVTLICPGKEAAGNATIHWVYSGSQSREWTTTGNTLVLRAVQVNDTGHYLCFLDDHLVGTVPLLVDVPPEEPKLSCFRKNPLVNAFCEWHPSSTPSPTTKAVMFAKKINTTNGKSDFQVPCQYSQQLKSFSCEVEILEGDKVYHIVSLCVANSVGSRSSHNVVFQSLKMVQPDPPANLVVSAIPGXPRWLKVSWQDPESWDPSYYLLQFELRYRPVWSKXFTVWPLQVAQHQCVIHDALRGVKHVVQVRGKEEFDIGQWSKWSPEVTGTPWLAEPRTTPAGIPGNPTQVSVEDYDNHEDQYGSSTEATSVLAPVQGSSPIPLPTFLVAGGSLAFGLLLCVFIILRLKKKWKSQAEKESKTTSPPPYPLGPLKPTFLLVPLLTPSGSHNSSGTDNTGSHSCLGVRDPQCPNDNSNRDYLFPR", "length": 462 }, "evidence": [ { "id": "A0A8V1ADN3", "url": "https://omabrowser.org/oma/group/A0A8V1ADN3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADN3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADN3" } ], "pmid": "" }, { "name": "ciliary neurotrophic factor receptor complex", "id": "GO:0070110", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070110", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADN3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADN3" } ], "pmid": "" }, { "name": "interleukin-6 receptor complex", "id": "GO:0005896", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005896", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADN3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADN3" } ], "pmid": "" }, { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADN3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADN3" } ], "pmid": "" }, { "name": "receptor complex", "id": "GO:0043235", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043235", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADN3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADN3" } ], "pmid": "" }, { "name": "external side of plasma membrane", "id": "GO:0009897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009897", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADN3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADN3" } ], "pmid": "" }, { "name": "apical plasma membrane", "id": "GO:0016324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016324", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADN3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADN3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 10, "go_terms": [ { "name": "cytokine receptor activity", "id": "GO:0004896", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004896", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADN3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADN3" } ], "pmid": "" }, { "name": "ciliary neurotrophic factor receptor activity", "id": "GO:0004897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004897", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADN3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADN3" } ], "pmid": "" }, { "name": "interleukin-6 receptor activity", "id": "GO:0004915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004915", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADN3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADN3" } ], "pmid": "" }, { "name": "interleukin-11 receptor activity", "id": "GO:0004921", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004921", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADN3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADN3" } ], "pmid": "" }, { "name": "interleukin-11 binding", "id": "GO:0019970", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019970", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADN3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADN3" } ], "pmid": "" }, { "name": "interleukin-6 binding", "id": "GO:0019981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019981", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADN3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADN3" } ], "pmid": "" }, { "name": "ciliary neurotrophic factor binding", "id": "GO:0070119", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070119", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADN3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADN3" } ], "pmid": "" }, { "name": "enzyme binding", "id": "GO:0019899", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019899", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADN3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADN3" } ], "pmid": "" }, { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADN3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADN3" } ], "pmid": "" }, { "name": "interleukin-6 receptor binding", "id": "GO:0005138", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005138", "evidence": [ { "database": 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"MYGSARTISNLEGSPSRSPRLPRSPRLGHRRTSSGGGGGTGKTLSMENIQSLNAAYATSGPMYLSDHEGVASTTFPKGTMTLGRATNRAVYGGRVTAMGSSPNIASAGLSHTDVLSYTDQHGGLTTSSHHHHHQVPSMLRQVRDSTMLDLQAQLKELQRENDLLRKELDIKDSKLGSSMNSIKTFWSPELKKERVLRKEEAARMSVLKEQMRVSHEENQHLQMTIQALQDELRTQRDLNHLLQQESGNRGAEHFTIELTEENFRRLQAEHDRQAKELFLLRKTLEEMELRIETQKQTLNARDESIKKLLEMLQSKGLPSKGMEDDNERTRRMAEAESQVNHLEVILDQKEKENIHLREELHRRTQLQPEPAKTKALQTVIEMKDTKIASLERNIRDLEDEIQMLKTNGVLNTEDREEEIKQIEVYKSHSKFMKNKIDQLKQELSKKESELLALQTKLETLSNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETFLNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEALSEKERIIERLKEQRERDDRERLEEIESYKKENKDLKEKVNALQAELTEKESSLIDLKEHASSLASAGLKRDSKLKSLEIAIEQKKEECSKLEAQLKKAHEAEEEARMNPEFADRMKQLDKEASYYREECGKAQAEVDRLLEILKEVENEKNDKDKKIAELERHMKDQNKKVANLKHSQQLEKKKNAQLLEEVRRREDNMTDNSQHLQVEELMNALEKTRQELDSTKARLASTQQSLAEKEAHLANLRIERRKQLEEILEMKQEALLAAISEKDANIALLELSASKKKKTQEEVMALKREKDRLVHQLKQQTQNRMKLMADNYDDDHHHYHHHHHHHHHRSPGRPQHSNHRPSPDQMIQSLLEAHSHGKISCCTLITCPTFA", "length": 971, "header": "tr|A0A1D5NYM8-1|A0A1D5NYM8_CHICK Computationally mapped isoform of ELKS/RAB6-interacting/CAST family member 2 OS=Gallus gallus OX=9031 GN=ERC2 PE=4 SV=1 CANONICAL=A0A8V1AAW1-1" }, "locus": { "chromosome": "12", "start_pos": 8521352, "end_pos": 8167590, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067593.1", "url": "https://www.ensembl.org/id/ENSGALT00010067593.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041336.1", "url": "https://www.ensembl.org/id/ENSGALP00010041336.1" } ] } }, { "isoform_ac": "A0A8V1A608-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAW1/entry#A0A8V1A608-1", "sequence": { "sequence": "MYGSARTISNLEGSPSRSPRLPRSPRLGHRRTSSGGGGGTGKTLSMENIQSLNAAYATSGPMYLSDHEGVASTTFPKGTMTLGRATNRAVYGGRVTAMGSSPNIASAGLSHTDVLSYTDQHGGLTTSSHHHHHQVPSMLRQVRDSTMLDLQAQLKELQRENDLLRKELDIKDSKLGSSMNSIKTFWSPELKKERVLRKEEAARMSVLKEQMRVSHEENQHLQMTIQALQDELRTQRDLNHLLQQESGNRGAEHFTIELTEENFRRLQAEHDRQAKELFLLRKTLEEMELRIETQKQTLNARDESIKKLLEMLQSKGLPSKGMEDDNERTRRMAEAESQVNHLEVILDQKEKENIHLREELHRRTQLQPEPAKTKALQTVIEMKDTKIASLERNIRDLEDEIQMLKTNGVLNTEDREEEIKQIEVYKSHSKFMKNKIDQLKQELSKKESELLALQTKLETLSNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETFLNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEALSEKERIIERLKEQRERDDRERLEEIESYKKENKDLKEKVNALQAELTEKESSLIDLKEHASSLASAGLKRDSKLKSLEIAIEQKKEECSKLEAQLKKQAEQLFNQMYNPMPIRNNGKQGAHEAEEEARMNPEFADRMKQLDKEASYYREECGKAQAEVDRLLEILKEVENEKNDKDKKIAELERHMKDQNKKVANLKHSQQLEKKKNAQLLEEVRRREDNMTDNSQHLQVEELMNALEKTRQELDSTKARLASTQQSLAEKEAHLANLRIERRKQLEEILEMKQEALLAAISEKDANIALLELSASKKKKTQEEVMALKREKDRLVHQLKQQTQNRMKLMADNYDDDHHHYHHHHHHHHHRSPGRPQHSNHRPSPDQLQAFLYTMSNCSCQRN", "length": 983, "header": "tr|A0A8V1A608-1|A0A8V1AAW1_CHICK Computationally mapped isoform of ELKS/RAB6-interacting/CAST family member 2 OS=Gallus gallus OX=9031 GN=ERC2 PE=4 SV=1 CANONICAL=A0A8V1AAW1-1" }, "locus": { "chromosome": "12", "start_pos": 8521352, "end_pos": 8112183, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067600.1", "url": "https://www.ensembl.org/id/ENSGALT00010067600.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041343.1", "url": "https://www.ensembl.org/id/ENSGALP00010041343.1" } ] } }, { "isoform_ac": "A0A8V1AAW1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAW1/entry#A0A8V1AAW1-1", "sequence": { "sequence": "MYGSARTISNLEGSPSRSPRLPRSPRLGHRRTSSGGGGGTGKTLSMENIQSLNAAYATSGPMYLSDHEGVASTTFPKGTMTLGRATNRAVYGGRVTAMGSSPNIASAGLSHTDVLSYTDQHGGLTTSSHHHHHQVPSMLRQVRDSTMLDLQAQLKELQRENDLLRKELDIKDSKLGSSMNSIKTFWSPELKKERVLRKEEAARMSVLKEQMRVSHEENQHLQMTIQALQDELRTQRDLNHLLQQESGNRGAEHFTIELTEENFRRLQAEHDRQAKELFLLRKTLEEMELRIETQKQTLNARDESIKKLLEMLQSKGLPSKGMEDDNERTRRMAEAESQVNHLEVILDQKEKENIHLREELHRRTQLQPEPAKTKALQTVIEMKKEPPLCIDPAVIFQDTKIASLERNIRDLEDEIQMLKTNGVLNTEDREEEIKQIEVYKSHSKFMKNKIDQLKQELSKKESELLALQTKLETLSNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETFLNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEALSEKERIIERLKEQRERDDRERLEEIESYKKENKDLKEKVNALQAELTEKESSLIDLKEHASSLASAGLKRDSKLKSLEIAIEQKKEECSKLEAQLKKQAEQLFNQMYNPAHEAEEEARMNPEFADRMKQLDKEASYYREECGKAQAEVDRLLEILKEVENEKNDKDKKIAELERHMKDQNKKVANLKHSQQLEKKKNAQLLEEVRRREDNMTDNSQHLQVEELMNALEKTRQELDSTKARLASTQQSLAEKEAHLANLRIERRKQLEEILEMKQEALLAAISEKDANIALLELSASKKKKTQEEVMALKREKDRLVHQLKQQTQNRMKLMADNYDDDHHHYHHHHHHHHHRSPGRPQHSNHRPSPDQMIQSLLEAHSHGKISCCTLITCPTFA", "length": 997, "header": "tr|A0A8V1AAW1-1|A0A8V1AAW1_CHICK Isoform 1 of ELKS/RAB6-interacting/CAST family member 2 OS=Gallus gallus OX=9031 GN=ERC2 PE=4 SV=1 CANONICAL=A0A8V1AAW1-1" }, "locus": { "chromosome": "12", "start_pos": 8521352, "end_pos": 8167590, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067592.1", "url": "https://www.ensembl.org/id/ENSGALT00010067592.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041335.1", "url": "https://www.ensembl.org/id/ENSGALP00010041335.1" } ] } }, { "isoform_ac": "A0A8V1AAW6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAW1/entry#A0A8V1AAW6-1", "sequence": { "sequence": "MYGSARTISNLEGSPSRSPRLPRSPRLGHRRTSSGGGGGTGKTLSMENIQSLNAAYATSGPMYLSDHEGVASTTFPKGTMTLGRATNRAVYGGRVTAMGSSPNIASAGLSHTDVLSYTDQHGGLTTSSHHHHHQVPSMLRQVRDSTMLDLQAQLKELQRENDLLRKELDIKDSKLGSSMNSIKTFWSPELKKERVLRKEEAARMSVLKEQMRVSHEENQHLQMTIQALQDELRTQRDLNHLLQQESGNRGAEHFTIELTEENFRRLQAEHDRQAKELFLLRKTLEEMELRIETQKQTLNARDESIKKLLEMLQSKGLPSKGMEDDNERTRRMAEAESQVNHLEVILDQKEKENIHLREELHRRTQLQPEPAKTKALQTVIEMKDTKIASLERNIRDLEDEIQMLKTNGVLNTEDREEEIKQIEVYKSHSKFMKNKIDQLKQELSKKESELLALQTKLETLSNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETFLNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEALSEKERIIERLKEQRERDDRERLEEIESYKKENKDLKEKVNALQAELTEKESSLIDLKEHASSLASAGLKRDSKLKSLEIAIEQKKEECSKLEAQLKKQAEQLFNQMYNPAHEAEEEARMNPEFADRMKQLDKEASYYREECGKAQAEVDRLLEILKEVENEKNDKDKKIAELESLTSRHMKDQNKKVANLKHSQQLEKKKNAQLLEEVRRREDNMTDNSQHLQVEELMNALEKTRQELDSTKARLASTQQSLAEKEAHLANLRIERRKQLEEILEMKQEALLAAISEKDANIALLELSASKKKKTQEEVMALKREKDRLVHQLKQQTQNRMKLMADNYDDDHHHYHHHHHHHHHRSPGRPQHSNHRPSPDQDDEEGIWA", "length": 969, "header": "tr|A0A8V1AAW6-1|A0A8V1AAW6_CHICK Computationally mapped isoform of ELKS/RAB6-interacting/CAST family member 2 OS=Gallus gallus OX=9031 GN=ERC2 PE=4 SV=1 CANONICAL=A0A8V1AAW1-1" }, "locus": { "chromosome": "12", "start_pos": 8521352, "end_pos": 8219314, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067597.1", "url": "https://www.ensembl.org/id/ENSGALT00010067597.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041340.1", "url": "https://www.ensembl.org/id/ENSGALP00010041340.1" } ] } }, { "isoform_ac": "A0A8V1AAX1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAW1/entry#A0A8V1AAX1-1", "sequence": { "sequence": "MYGSARTISNLEGSPSRSPRLPRSPRLGHRRTSSGGGGGTGKTLSMENIQSLNAAYATSGPMYLSDHEGVASTTFPKGTMTLGRATNRAVYGGRVTAMGSSPNIASAGLSHTDVLSYTDQHGGLTTSSHHHHHQVPSMLRQVRDSTMLDLQAQLKELQRENDLLRKELDIKDSKLGSSMNSIKTFWSPELKKERVLRKEEAARMSVLKEQMRVSHEENQHLQMTIQALQDELRTQRDLNHLLQQESGNRGAEHFTIELTEENFRRLQAEHDRQAKELFLLRKTLEEMELRIETQKQTLNARDESIKKLLEMLQSKGLPSKGMEDDNERTRRMAEAESQVNHLEVILDQKEKENIHLREELHRRTQLQPEPAKTKALQTVIEMKDTKIASLERNIRDLEDEIQMLKTNGVLNTEDREEEIKQIEVYKSHSKFMKNKIDQLKQELSKKESELLALQTKLETLSNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETFLNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEALSEKERIIERLKEQRERDDRERLEEIESYKKENKDLKEKVNALQAELTEKESSLIDLKEHASSLASAGLKRDSKLKSLEIAIEQKKEECSKLEAQLKKAHEAEEEARMNPEFADRMKQLDKEASYYREECGKAQAEVDRLLEILKEVENEKNDKDKKIAELERHMKDQNKKVANLKHSQQLEKKKNAQLLEEVRRREDNMTDNSQHLQVEELMNALEKTRQELDSTKARLASTQQSLAEKEAHLANLRIERRKQLEEILEMKQEALLAAISEKDANIALLELSASKKKKTQEEVMALKREKDRLVHQLKQQTQNRMKLMADNYDDDHHHYHHHHHHHHHRSPGRPQHSNHRPSPDQLSEELVKEEEKM", "length": 957, "header": "tr|A0A8V1AAX1-1|A0A8V1AAX1_CHICK Computationally mapped isoform of ELKS/RAB6-interacting/CAST family member 2 OS=Gallus gallus OX=9031 GN=ERC2 PE=4 SV=1 CANONICAL=A0A8V1AAW1-1" }, "locus": { "chromosome": "12", "start_pos": 8521352, "end_pos": 8112160, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067602.1", "url": "https://www.ensembl.org/id/ENSGALT00010067602.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041345.1", "url": "https://www.ensembl.org/id/ENSGALP00010041345.1" } ] } }, { "isoform_ac": "A0A8V1ADN7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAW1/entry#A0A8V1ADN7-1", "sequence": { "sequence": "MYGSARTISNLEGSPSRSPRLPRSPRLGHRRTSSGGGGGTGKTLSMENIQSLNAAYATSGPMYLSDHEGVASTTFPKGTMTLGRATNRAVYGGRVTAMGSSPNIASAGLSHTDVLSYTDQHGGLTTSSHHHHHQVPSMLRQVRDSTMLDLQAQLKELQRENDLLRKELDIKDSKLGSSMNSIKTFWSPELKKERVLRKEEAARMSVLKEQMRVSHEENQFLDARRTKHLQMTIQALQDELRTQRDLNHLLQQESGNRGAEHFTIELTEENFRRLQAEHDRQAKELFLLRKTLEEMELRIETQKQTLNARDESIKKLLEMLQSKGLPSKGMEDDNERTRRMAEAESQVNHLEVILDQKEKENIHLREELHRRTQLQPEPAKTKALQTVIEMKDTKIASLERNIRDLEDEIQMLKTNGVLNTEDREEEIKQIEVYKSHSKFMKNKIDQLKQELSKKESELLALQTKLETLSNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETFLNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEALSEKERIIERLKEQRERDDRERLEEIESYKKENKDLKEKVNALQAELTEKESSLIDLKEHASSLASAGLKRDSKLKSLEIAIEQKKEECSKLEAQLKKQAEQLFNQMYNPMPIRNNGKQGAHEAEEEARMNPEFADRMKQLDKEASYYREECGKAQAEVDRLLEILKEVENEKNDKDKKIAELESLTSRHMKDQNKKVANLKHSQQLEKKKNAQLLEEVRRREDNMTDNSQHLQVEELMNALEKTRQELDSTKARLASTQQSLAEKEAHLANLRIERRKQLEEILEMKQEALLAAISEKDANIALLELSASKKKKTQEEVMALKREKDRLVHQLKQQTQNRMKLMADNYDDDHHHYHHHHHHHHHRSPGRPQHSNHRPSPDQDDEEGIWA", "length": 987, "header": "tr|A0A8V1ADN7-1|A0A8V1ADN7_CHICK Computationally mapped isoform of ELKS/RAB6-interacting/CAST family member 2 OS=Gallus gallus OX=9031 GN=ERC2 PE=4 SV=1 CANONICAL=A0A8V1AAW1-1" }, "locus": { "chromosome": "12", "start_pos": 8521352, "end_pos": 8219314, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067594.1", "url": "https://www.ensembl.org/id/ENSGALT00010067594.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041337.1", "url": "https://www.ensembl.org/id/ENSGALP00010041337.1" } ] } }, { "isoform_ac": "A0A8V1AI24-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAW1/entry#A0A8V1AI24-1", "sequence": { "sequence": "MYGSARTISNLEGSPSRSPRLPRSPRLGHRRTSSGGGGGTGKTLSMENIQSLNAAYATSGPMYLSDHEGVASTTFPKGTMTLGRATNRAVYGGRVTAMGSSPNIASAGLSHTDVLSYTDQHGGLTTSSHHHHHQVPSMLRQVRDSTMLDLQAQLKELQRENDLLRKELDIKDSKLGSSMNSIKTFWSPELKKERVLRKEEAARMSVLKEQMRVSHEENQHLQMTIQALQDELRTQRDLNHLLQQESGNRGAEHFTIELTEENFRRLQAEHDRQAKELFLLRKTLEEMELRIETQKQTLNARDESIKKLLEMLQSKGLPSKGMEDDNERTRRMAEAESQVNHLEVILDQKEKENIHLREELHRRTQLQPEPAKTKALQTVIEMKDTKIASLERNIRDLEDEIQMLKTNGVLNTEDREEEIKQIEVYKSHSKFMKNKIDQLKQELSKKESELLALQTKLETLSNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETFLNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEALSEKERIIERLKEQRERDDRERLEEIESYKKENKDLKEKVNALQAELTEKETHEGPKQEGCQSEAQSATGEKKECTAVGRSS", "length": 671, "header": "tr|A0A8V1AI24-1|A0A8V1AAW1_CHICK Computationally mapped isoform of ELKS/RAB6-interacting/CAST family member 2 OS=Gallus gallus OX=9031 GN=ERC2 PE=4 SV=1 CANONICAL=A0A8V1AAW1-1" }, "locus": { "chromosome": "12", "start_pos": 8521352, "end_pos": 8350080, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067591.1", "url": "https://www.ensembl.org/id/ENSGALT00010067591.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041334.1", "url": "https://www.ensembl.org/id/ENSGALP00010041334.1" } ] } }, { "isoform_ac": "E1C853-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAW1/entry#E1C853-1", "sequence": { "sequence": "MYGSARTISNLEGSPSRSPRLPRSPRLGHRRTSSGGGGGTGKTLSMENIQSLNAAYATSGPMYLSDHEGVASTTFPKGTMTLGRATNRAVYGGRVTAMGSSPNIASAGLSHTDVLSYTDQHGGLTTSSHHHHHQVPSMLRQVRDSTMLDLQAQLKELQRENDLLRKELDIKDSKLGSSMNSIKTFWSPELKKERVLRKEEAARMSVLKEQMRVSHEENQHLQMTIQALQDELRTQRDLNHLLQQESGNRGAEHFTIELTEENFRRLQAEHDRQAKELFLLRKTLEEMELRIETQKQTLNARDESIKKLLEMLQSKGLPSKGMEDDNERTRRMAEAESQVNHLEVILDQKEKENIHLREELHRRTQLQPEPAKTKALQTVIEMKDTKIASLERNIRDLEDEIQMLKTNGVLNTEDREEEIKQIEVYKSHSKFMKNKIDQLKQELSKKESELLALQTKLETLSNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETFLNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEALSEKERIIERLKEQRERDDRERLEEIESYKKENKDLKEKVNALQAELTEKESSLIDLKEHASSLASAGLKRDSKLKSLEIAIEQKKEECSKLEAQLKKQAEQLFNQMYNPMPIRNNGKQGAHEAEEEARMNPEFADRMKQLDKEASYYREECGKAQAEVDRLLEILKEVENEKNDKDKKIAELESLTSRHMKDQNKKVANLKHSQQLEKKKNAQLLEEVRRREDNMTDNSQHLQVEELMNALEKTRQELDSTKARLASTQQSLAEKEAHLANLRIERRKQLEEILEMKQEALLAAISEKDANIALLELSASKKKKTQEEVMALKREKDRLVHQLKQQTQNRMKLMADNYDDDHHHYHHHHHHHHHRSPGRPQHSNHRPSPDQDDEEGIWA", "length": 979, "header": "tr|E1C853-1|A0A8V1AAW1_CHICK Computationally mapped isoform of ELKS/RAB6-interacting/CAST family member 2 OS=Gallus gallus OX=9031 GN=ERC2 PE=4 SV=3 CANONICAL=A0A8V1AAW1-1" }, "locus": { "chromosome": "12", "start_pos": 8521352, "end_pos": 8219314, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067596.1", "url": "https://www.ensembl.org/id/ENSGALT00010067596.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041339.1", "url": "https://www.ensembl.org/id/ENSGALP00010041339.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8W4FDF0-1", "protein_name": "ELKS/RAB6-interacting/CAST family member 2", "gene_name": "ERC2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MYGSARTITNLEGSPSRSPRLPRSPRLGHRRTSSGGGGGTGKTLSMENIQSLNAAYATSGPMYLSDHEGVASTTYPKGTMTLGRATNRAVYGGRVTAMGSSPNIASAGLSHTDVLSYTDQHGGLTSSSHHHHHQVPSMLRQVRDSTMLDLQAQLKELQRENDLLRKELDIKDSKLGSSMNSIKTFWSPELKKERVLRKEEAARMSVLKEQMRVSHEENQHLQLTIQALQDELRTQRDLNHLLQQESGNRGAEHFTIELTEENFRRLQAEHDRQAKELFLLRKTLEEMELRIETQKQTLNARDESIKKLLEMLQSKGLPSKSLEDDNERTRRMAEAESQVSHLEVILDQKEKENIHLREELHRRSQLQPEPAKTKALQTVIEMKDTKIASLERNIRDLEDEIQMLKANGVLNTEDREEEIKQIEVYKSHSKFMKTKIDQLKQELSKKESELLALQTKLETLSNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEALSEKERIIERLKEQRERDDRERLEEIESFRKENKDLKEKVNALQAELTEKESSLIDLKEHASSLASAGLKRDSKLKSLEIAIEQKKEECSKLEAQLKKAHNIEDDSRMNPEFADRIKQLDKEASYYRDECGKAQAEVDRLLEILKEVENEKNDKDKKIAELESLTFRHMKDQNKKVANLKHNQQLEKKKNAQLLEEVRRREDTMADNSQHLQIEELMNALEKTRQELDATKARLASTQQSLAEKEAHLANLRIERRKQLEEILEMKQEALLAAISEKDANIALLELSASKKKKTQEEVMALKREKDRLVHQLKQQTQNRMKLMADNYDEDHHHYHHHHHHHHHRSPGRSQHSNHRPSPDQDDEEGIWA", "length": 957 }, "evidence": [ { "id": "A0A8V1AAW1", "url": "https://omabrowser.org/oma/group/A0A8V1AAW1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O15083-1", "protein_name": "ERC protein 2", "gene_name": "ERC2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MYGSARTITNLEGSPSRSPRLPRSPRLGHRRTSSGGGGGTGKTLSMENIQSLNAAYATSGPMYLSDHEGVASTTYPKGTMTLGRATNRAVYGGRVTAMGSSPNIASAGLSHTDVLSYTDQHGGLTGSSHHHHHQVPSMLRQVRDSTMLDLQAQLKELQRENDLLRKELDIKDSKLGSSMNSIKTFWSPELKKERVLRKEEAARMSVLKEQMRVSHEENQHLQLTIQALQDELRTQRDLNHLLQQESGNRGAEHFTIELTEENFRRLQAEHDRQAKELFLLRKTLEEMELRIETQKQTLNARDESIKKLLEMLQSKGLPSKSLEDDNERTRRMAEAESQVSHLEVILDQKEKENIHLREELHRRSQLQPEPAKTKALQTVIEMKDTKIASLERNIRDLEDEIQMLKANGVLNTEDREEEIKQIEVYKSHSKFMKTKIDQLKQELSKKESELLALQTKLETLSNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEALSEKERIIERLKEQRERDDRERLEEIESFRKENKDLKEKVNALQAELTEKESSLIDLKEHASSLASAGLKRDSKLKSLEIAIEQKKEECSKLEAQLKKAHNIEDDSRMNPEFADQIKQLDKEASYYRDECGKAQAEVDRLLEILKEVENEKNDKDKKIAELESLTLRHMKDQNKKVANLKHNQQLEKKKNAQLLEEVRRREDSMADNSQHLQIEELMNALEKTRQELDATKARLASTQQSLAEKEAHLANLRIERRKQLEEILEMKQEALLAAISEKDANIALLELSASKKKKTQEEVMALKREKDRLVHQLKQQTQNRMKLMADNYDDDHHHYHHHHHHHHHRSPGRSQHSNHRPSPDQDDEEGIWA", "length": 957 }, "evidence": [ { "id": "A0A8V1AAW1", "url": "https://omabrowser.org/oma/group/A0A8V1AAW1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6PH08-1", "protein_name": "ERC protein 2", "gene_name": "Erc2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MYGSARTISNLEGSPSRSPRLPRSPRLGHRRTSSGGGGGTGKTLSMENIQSLNAAYATSGPMYLSDHEGVASTTYPKGTMTLGRATNRAVYGGRVTAMGSSPNIASAGLSHTDVLSYTDQHGGLSGSSHHHHHQVPSMLRQVRDSTMLDLQAQLKELQRENDLLRKELDIKDSKLGSSMNSIKTFWSPELKKERVLRKEEAARMSVLKEQMRVSHEENQHLQLTIQALQDELRTQRDLNHLLQQESGNRGAEHFTIELTEENFRRLQAEHDRQAKELFLLRKTLEEMELRIETQKQTLNARDESIKKLLEMLQSKGLPSKSLEDDNERTRRMAEAESQVSHLEVILDQKEKENIHLREELHRRSQLQPEPAKTKALQTVIEMKDTKIASLERNIRDLEDEVQMLKANGVLNTEDREEEIKQIEVYKSHSKFMKTKIDQLKQELSKKESELLALQTKLETLSNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEALSEKERIIERLKEQRERDDRERLEEIESFRKENKDLKEKVNALQAELTEKESSLIDLKEHASSLASAGLKRDSKLKSLEIAIEQKKEECNKLEAQLKKAHNIEDDSRMNPEFADRLKQLDKEASYYRDECGKAQAEVDRLLEILKEVENEKNDKDKKIAELESLTLRHMKDQNKKVANLKYNQQLEKKKNAQLLEEVRRREDSMVDNSQHLQIEELMNALEKTRQELDATKARLASTQQSLAEKEAHLANLRIERRKQLEEILEMKQEALLAAISEKDANIALLELSASKKKKTQEEVMALKREKDRLVHQLKQQTQNRMKLMADNYDEDHHHYHHHHHHHHHRSPGRSQHSNHRPSPDQDDEEGIWA", "length": 957 }, "evidence": [ { "id": "A0A8V1AAW1", "url": "https://omabrowser.org/oma/group/A0A8V1AAW1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8K3M6-1", "protein_name": "ERC protein 2", "gene_name": "Erc2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MYGSARTISNPEGSPSRSPRLPRSPRLGHRRTSSGGGGGTGKTLSMENIQSLNAAYATSGPMYLSDHEGVASTTYPKGTMTLGRATNRAVYGGRVTAMGSSPNIASAGLSHTDVLSYTDQHGGLGGSSHHHHHQVPSMLRQVRDSTMLDLQAQLKELQRENDLLRKELDIKDSKLGSSMNSIKTFWSPELKKERVLRKEEAARMSVLKEQMRVSHEENQHLQLTIQALQDELRTQRDLNHLLQQESGNRGAEHFTIELTEENFRRLQAEHDRQAKELFLLRKTLEEMELRIETQKQTLNARDESIKKLLEMLQSKGLPSKSLEDDNERTRRMAEAESQVSHLEVILDQKEKENIHLREELHRRSQLQPEPAKTKALQTVIEMKDTKIASLERNIRDLEDEIQMLKANGVLNTEDREEEIKQIEVYKSHSKFMKTKNDQLKQELSKKESELLALQTKLETLSNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEALSEKERIIERLKEQRERDDRERLEEIESFRKENKDLKEKVNALQAELTEKESSLIDLKEHASSLASAGLKRDSKLKSLEIAIEQKKEECNKLEAQLKKAHNIEDDSRMNPEFADRLKQLDKEASYYRDECGKAQAEVDRLLEILKEVENEKNDKDKKIAELESLTLRHMKDQNKKVANLKHNQQLEKKKNAQLLEEVRRREFSMVDNSQHLQIEELMNALEKTRQELDATKARLASTQQSLAEKEAHLANLRMERRKQLEEILEMKQEALLAAISEKDANIALLELSASKKKKTQEEVMALKREKDRLVHQLKQQTQNRMKLMADNYDDDHHHYHHHHHHHHHRSPGRSQHSNHRPSPDQDDEEGIWA", "length": 957 }, "evidence": [ { "id": "A0A8V1AAW1", "url": "https://omabrowser.org/oma/group/A0A8V1AAW1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAW1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAW1" } ], "pmid": "" }, { "name": "presynapse", "id": "GO:0098793", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098793", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAW1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAW1" } ], "pmid": "" }, { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAW1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAW1" } ], "pmid": "" }, { "name": "GABA-ergic synapse", "id": "GO:0098982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098982", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAW1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAW1" } ], "pmid": "" }, { "name": "presynaptic active zone cytoplasmic component", "id": "GO:0098831", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098831", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAW1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAW1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "structural constituent of presynaptic active zone", "id": "GO:0098882", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098882", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAW1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAW1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "maintenance of presynaptic active zone structure", "id": "GO:0048790", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048790", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAW1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAW1" } ], "pmid": "" }, { "name": "regulation of presynaptic cytosolic calcium ion concentration", "id": "GO:0099509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099509", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAW1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAW1" } ], "pmid": "" }, { "name": "synaptic vesicle priming", "id": "GO:0016082", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016082", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAW1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAW1" } ], "pmid": "" }, { "name": "regulation of calcium-dependent activation of synaptic vesicle fusion", "id": "GO:0150037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0150037", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAW1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAW1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 814, "end_pos": 816, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 814, "end_pos": 816 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1ADP4-1", "uniprot_ac": "A0A8V1ADP4", "uniprot_id": "A0A8V1ADP4_CHICK", "mass": { "chemical_mass": 66572.0, "monoisotopic_mass": 66572.0 }, "refseq": {}, "gene_names": [ { "name": "CSRNP1", "type": "recommended", "evidence": [ { "id": "A0A8V1ADP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADP4" } ] } ], "protein_names": [ { "name": "Cysteine and serine rich nuclear protein 1", "type": "synonym", "evidence": [ { "id": "A0A8V1ADP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADP4/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADP4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADP4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CSRNP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADP4", "locus": { "chromosome": "2", "start_pos": 5263505, "end_pos": 5253755, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010026696", "url": "https://www.ensembl.org/id/ENSGALG00010026696" } ] } } ], "crossref": [ { "id": "A0A8V1ADP4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1ADP4", "database": "AlphaFoldDB", "categories": [] }, { "id": "420425", "url": "https://www.ncbi.nlm.nih.gov/gene/420425", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR023260", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023260", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031972", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031972", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:420425", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420425", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CGCDCRE", "url": "https://omabrowser.org/oma/group/CGCDCRE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A6A8", "url": "https://www.orthodb.org/?gene=A0A8V1A6A8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A8R3", "url": "https://www.orthodb.org/?gene=A0A8V1A8R3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A8R7", "url": "https://www.orthodb.org/?gene=A0A8V1A8R7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ADP4", "url": "https://www.orthodb.org/?gene=A0A8V1ADP4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13580", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13580", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13580:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13580:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF16019", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16019", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1A6A8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6A8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A6A8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6A8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A8R3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8R3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A8R3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8R3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A8R7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8R7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A8R7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8R7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ADP4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADP4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ADP4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADP4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MWTRRYFILDFISEVSFISRHLELYERYGVTMSGVLKRKYEELGDDSTYCSSSSCSPLSSSASSGWDSDEDSSRGDSKPSSAIAPGFTPTSILKKSKRLKKNNVEFDRVTVFYFPRCQGFTSVPSRGGCTLGMVSKHSSSRQFTLAEFSKEQENIRREKLEEKLKEEKLEALKWKLTMNGTKESEEANQLTIEDISDDDIDVSNVDLEDGFFLQPYPAKKRRALLKAVGVKKIDKEEKRELHSIRLSREDCGCDCQEVCDPETCSCSLAGIKCQMDHTSFPCGCTKDGCGNTEGRIEFNQARVQTHFIHTIMKLELEKQQQSSEGVAEVEPPFRERLPQLGCAAAKGPLEERTAPLAPAFQFSPELEALGENSCSSDMTDSSISSHPSEDLEEPYESLPSDKSQSDIDDDGLARILHFNDSDAEEEGDRCQDNLSCFHPADFFIEDHGCEAKPGPGASSHLSECLDENANQDSGGLLEEAMHVCCDGVSCCAPAPAESCSKSYADLSLSSDSLDFFQSFSDYNLGPLYNSLKEYENLDNFSALQFQLPNFPGFPQAGDQGSCFLESLIGLSESVPETPAPFTDNQLLEDAIKSSLMETVKV", "length": 601, "header": "tr|A0A8V1ADP4-1|A0A8V1ADP4_CHICK Isoform 1 of Cysteine and serine rich nuclear protein 1 OS=Gallus gallus OX=9031 GN=CSRNP1 PE=3 SV=1 CANONICAL=A0A8V1ADP4-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A6A8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADP4/entry#A0A8V1A6A8-1", "sequence": { "sequence": "MMLFSFLLQLYERYGVTMSGVLKRKYEELGDDSTYCSSSSCSPLSSSASSGWDSDEDSSRGDSKPSSAIAPGFTPTSILKKSKRLKKNNVEFDRVTVFYFPRCQGFTSVPSRGGCTLGMVSKHSSSRQFTLAEFSKEQENIRREKLEEKLKEEKLEALKWKLTMNGTKESEEANQLTIEDISDDDIDVSNVDLEDGFFLQPYPAKKRRALLKAVGVKKIDKEEKRELHSIRLSREDCGCDCQEVCDPETCSCSLAGIKCQMDHTSFPCGCTKDGCGNTEGRIEFNQARVQTHFIHTIMKLELEKQQQSSEGVAEVEPPFRERLPQLGCAAAKGPLEERTAPLAPAFQFSPELEALGENSCSSDMTDSSISSHPSEDLEEPYESLPSDKSQSDIDDDGLARILHFNDSDAEEEGDRCQDNLSCFHPADFFIEDHGCEAKPGPGASSHLSECLDENANQDSGGLLEEAMHVCCDGVSCCAPAPAESCSKSYADLSLSSDSLDFFQSFSDYNLGPLYNSLKEYENLDNFSALQFQLPNFPGFPQAGDQGSCFLESLIGLSESVPETPAPFTDNQLLEDAIKSSLMETVKV", "length": 587, "header": "tr|A0A8V1A6A8-1|A0A8V1ADP4_CHICK Computationally mapped isoform of Cysteine and serine rich nuclear protein 1 OS=Gallus gallus OX=9031 GN=CSRNP1 PE=3 SV=1 CANONICAL=A0A8V1ADP4-1" }, "locus": { "chromosome": "2", "start_pos": 5260714, "end_pos": 5255041, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010064783.1", "url": "https://www.ensembl.org/id/ENSGALT00010064783.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039619.1", "url": "https://www.ensembl.org/id/ENSGALP00010039619.1" } ] } }, { "isoform_ac": "A0A8V1A8R3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADP4/entry#A0A8V1A8R3-1", "sequence": { "sequence": "MAQPGLKPSASEQKLLTQLATSILKKSKRLKKNNVEFDRVTVFYFPRCQGFTSVPSRGGCTLGMVSKHSSSRQFTLAEFSKEQENIRREKLEEKLKEEKLEALKWKLTMNGTKESEEANQLTIEDISDDDIDVSNVDLEDGFFLQPYPAKKRRALLKAVGVKKIDKEEKRELHSIRLSREDCGCDCQEVCDPETCSCSLAGIKCQMDHTSFPCGCTKDGCGNTEGRIEFNQARVQTHFIHTIMKLELEKQQQSSEGVAEVEPPFRERLPQLGCAAAKGPLEERTAPLAPAFQFSPELEALGENSCSSDMTDSSISSHPSEDLEEPYESLPSDKSQSDIDDDGLARILHFNDSDAEEEGDRCQDNLSCFHPADFFIEDHGCEAKPGPGASSHLSECLDENANQDSGGLLEEAMHVCCDGVSCCAPAPAESCSKSYADLSLSSDSLDFFQSFSDYNLGPLYNSLKEYENLDNFSALQFQLPNFPGFPQAGDQGSCFLESLIGLSESVPETPAPFTDNQLLEDAIKSSLMETVKV", "length": 532, "header": "tr|A0A8V1A8R3-1|A0A8V1ADP4_CHICK Computationally mapped isoform of Cysteine and serine rich nuclear protein 1 OS=Gallus gallus OX=9031 GN=CSRNP1 PE=3 SV=1 CANONICAL=A0A8V1ADP4-1" }, "locus": { "chromosome": "2", "start_pos": 5260714, "end_pos": 5256162, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010064777.1", "url": "https://www.ensembl.org/id/ENSGALT00010064777.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039616.1", "url": "https://www.ensembl.org/id/ENSGALP00010039616.1" } ] } }, { "isoform_ac": "A0A8V1A8R7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADP4/entry#A0A8V1A8R7-1", "sequence": { "sequence": "MQKRLYERYGVTMSGVLKRKYEELGDDSTYCSSSSCSPLSSSASSGWDSDEDSSRGDSKPSSAIAPGFTPTSILKKSKRLKKNNVEFDRVTVFYFPRCQGFTSVPSRGGCTLGMVSKHSSSRQFTLAEFSKEQENIRREKLEEKLKEEKLEALKWKLTMNGTKESEEANQLTIEDISDDDIDVSNVDLEDGFFLQPYPAKKRRALLKAVGVKKIDKEEKRELHSIRLSREDCGCDCQEVCDPETCSCSLAGIKCQMDHTSFPCGCTKDGCGNTEGRIEFNQARVQTHFIHTIMKLELEKQQQSSEGVAEVEPPFRERLPQLGCAAAKGPLEERTAPLAPAFQFSPELEALGENSCSSDMTDSSISSHPSEDLEEPYESLPSDKSQSDIDDDGLARILHFNDSDAEEEGDRCQDNLSCFHPADFFIEDHGCEAKPGPGASSHLSECLDENANQDSGGLLEEAMHVCCDGVSCCAPAPAESCSKSYADLSLSSDSLDFFQSFSDYNLGPLYNSLKEYENLDNFSALQFQLPNFPGFPQAGDQGSCFLESLIGLSESVPETPAPFTDNQLLEDAIKSSLMETVKV", "length": 582, "header": "tr|A0A8V1A8R7-1|A0A8V1ADP4_CHICK Computationally mapped isoform of Cysteine and serine rich nuclear protein 1 OS=Gallus gallus OX=9031 GN=CSRNP1 PE=3 SV=1 CANONICAL=A0A8V1ADP4-1" }, "locus": { "chromosome": "2", "start_pos": 5260714, "end_pos": 5254302, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010064787.1", "url": "https://www.ensembl.org/id/ENSGALT00010064787.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039621.1", "url": "https://www.ensembl.org/id/ENSGALP00010039621.1" } ] } }, { "isoform_ac": "A0A8V1ADP4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADP4/entry#A0A8V1ADP4-1", "sequence": { "sequence": "MWTRRYFILDFISEVSFISRHLELYERYGVTMSGVLKRKYEELGDDSTYCSSSSCSPLSSSASSGWDSDEDSSRGDSKPSSAIAPGFTPTSILKKSKRLKKNNVEFDRVTVFYFPRCQGFTSVPSRGGCTLGMVSKHSSSRQFTLAEFSKEQENIRREKLEEKLKEEKLEALKWKLTMNGTKESEEANQLTIEDISDDDIDVSNVDLEDGFFLQPYPAKKRRALLKAVGVKKIDKEEKRELHSIRLSREDCGCDCQEVCDPETCSCSLAGIKCQMDHTSFPCGCTKDGCGNTEGRIEFNQARVQTHFIHTIMKLELEKQQQSSEGVAEVEPPFRERLPQLGCAAAKGPLEERTAPLAPAFQFSPELEALGENSCSSDMTDSSISSHPSEDLEEPYESLPSDKSQSDIDDDGLARILHFNDSDAEEEGDRCQDNLSCFHPADFFIEDHGCEAKPGPGASSHLSECLDENANQDSGGLLEEAMHVCCDGVSCCAPAPAESCSKSYADLSLSSDSLDFFQSFSDYNLGPLYNSLKEYENLDNFSALQFQLPNFPGFPQAGDQGSCFLESLIGLSESVPETPAPFTDNQLLEDAIKSSLMETVKV", "length": 601, "header": "tr|A0A8V1ADP4-1|A0A8V1ADP4_CHICK Isoform 1 of Cysteine and serine rich nuclear protein 1 OS=Gallus gallus OX=9031 GN=CSRNP1 PE=3 SV=1 CANONICAL=A0A8V1ADP4-1" }, "locus": { "chromosome": "2", "start_pos": 5260714, "end_pos": 5253764, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010064790.1", "url": "https://www.ensembl.org/id/ENSGALT00010064790.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039623.1", "url": "https://www.ensembl.org/id/ENSGALP00010039623.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:420425", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420425", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "E9QH67-1", "protein_name": "Cysteine/serine-rich nuclear protein 1b isoform X1", "gene_name": "csrnp1b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSGVLKRKYEEVAEDPCYSSSSPSSLSSSAYSEWDSDGESCYSDTLDSTPSNPSSPATSLNTTSILKKAKRTRRGNVQFDQVTVFFFPRCQGFTSVPSRGGCTLGMMQRHSAQRRYTLAEFAIAQRHLRREKLKNRMREEKLEALKLKLTKNGTQESEEAEKLTVDDIPEDEIDLSGVNVDDGSFLHPYPSKKRYAILKAAGVKKIDREEKRQLHELRTSREDCGCDCQGFCEPETCSCSLAGIKCQMDHSSFPCGCTKDGCGNTQGRIEFNSSRVHTHYIHTIMKLELEKRLEEHTTETPPETHPDSSSLNQPAEISSTPDMPTFHFNSELLSTGENSCSSDMTDSSSSSGQSEDSESVENVPSEQSPLDVDENGLTRILSFSDTDNEDCSIRERNDNCDYQQKKSEGSMGYGIFSTEDDKLNMSQTDNSRTAMSELLDENANQGNGLFHSSFIPHTPSPSIDHSASYMDLSLSSESDLEFFDGFPCLGPSSLYNSLKEYEHVDNFFQFQLPTYPSLPQAVDPGTCLLESLIGLSDSVPEPPTTFTDNQMLEDAMKLSVMESLKV", "length": 566 }, "evidence": [ { "id": "A0A8V1ADP4", "url": "https://omabrowser.org/oma/group/A0A8V1ADP4/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1MDN9-1", "protein_name": "Cysteine and serine rich nuclear protein 1", "gene_name": "CSRNP1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTGLLKRKFDQLDEDSSSLCSSSSLSSSGHHSPSCSPSSSVSPAWDSDEESPWDQLPLPDGDFCGPRSFTPLSILKRAPRKRRGRVAFDGITVFYFPRCQGFTSVPSRGGCTLGMASRHSACRRFSLAEFTQEQARARQEKLRLRLKEEKLEALRWKLSETGVPKTEAGLPLTVDAIDDASVEEDLALAVAGGRLEEMTFLQPFPARKRRALLRASGVRRIDREEKRELQALRQSREDCGCRCDRVCDPETCSCSLAGIKCQMDHTAFPCGCCREGCENPKGRVEFNQARVQTHFIHTLTRLQLEQGAESLGELEAPAQGGTPSPGEQVLASAFPLAKPPVSSELGDNSCSSDMTDSSTASGTSEALDGPARLALPGPGFQPGVDDDGLARILSFSDSELGGHEEEEEDGGVGGLDNLSCFHPADIFGTGDLTGLASWTHSYSSSSLTSGILDENANLDASCFLNSGLEGLGEGSFPGPLVPASTDAGQSSSVDLSLSSCDSFELLQALPDYSLGPHYTSRKVSDSLDHLEVPHFTLPAFSPPADTSTCFLESIMGLTEPAAEALAPFVDGQLFEDTTPASLVEPVPV", "length": 588 }, "evidence": [ { "id": "A0A8V1ADP4", "url": "https://omabrowser.org/oma/group/A0A8V1ADP4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1SJR3-1", "protein_name": "Cysteine and serine rich nuclear protein 1", "gene_name": "CSRNP1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTGLLKRKFDQLDEDSSSLCSSSSLSSSGRCSPACSPSSSVSPAWDSDEESPWDQMPLPDRDFCCPRSFTPLSILKRAPRKRPGRVAFDGITVFYFPRCQGFTSVPSRGGCTLGMAPRHSACRRFSLAEFTQEQARARHEKLRLRLKEEKLEALQRKLSEAGVPKTEAGLSLTVDSIDDASVEEDLAVALAGGRLEEMTFLQPYPARQRRALLRAAGVRRIDREEKRELQALRQSREDCGCRCDRVCEPETCSCILAGIKCQMDHTAFPCGCCREGCENPKGRVEFNQARVQTHFIHTLTRLQLEQGAESLRELEAPAQGSIPSPSDQVLAPSFPLAKPPMSSKLGDNSCSSDMTDSSTTSGTSEAPDGPAHLTLPGPGLQPNMEDDSLARILSFSDSDLGGEEEEEEEGGVGSLDNLSCFHPADIFGTGDPAGLASWTHSYSSSSLASGILDENANLDASCFLNSGLDGSGESSLPGPLVPGSMDAGQSSSVDLSLSSCDSFELLQALPDYSLGPHYTSRKVSDSLDNLEAPHFALPAFSPPGDTSTCFLESIMGFSEPAAEALPPFVDSQLFEDTAPASLVEPVPV", "length": 588 }, "evidence": [ { "id": "A0A8V1ADP4", "url": "https://omabrowser.org/oma/group/A0A8V1ADP4/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P59054-1", "protein_name": "Cysteine/serine-rich nuclear protein 1", "gene_name": "Csrnp1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTGLLKRKFDQLEEDDSSSSSSSSFSSRLSLSSFPASSASPAWNSDEEGPGGQAPQSDQDSCGLQSFTPPSILKRAPRERPGHVAFNGITVYYFPRCQGFTSVPSRGGCTLGMASRHSTCRLFSLAEFTQEQVRARREKLRRRLKEEKLEMLRWKFSVAGVPESGAGVPLTADAIDDASVEEDLAVAVANGRLEEANFLQPHPPRQRRALLRASGVRRIDREEKRELQVLRQSREDCGCHCDGVCDPETCSCSLAGIKCQMDHTSFPCGCCREGCENPNGRVEFNQTRVQTHFIHTLTRLQMEQGAESLGDLESPVEDTPVEQAALSPFPPSKPPVSSELGDSSCSSDMTDSSTTLSSGSSEPPNHPAHPSLPGPSFRSGVDEDSLEQILNFSDSDLGIEEEEEEGGGVGNLDNLSCFHLADIFGTGDPGSLASWTHSQSGSSLASGILDENANLDASCFLNSGLGGLREGSLPGSSGSPEGDAVQSSSWDLSLSSCDSFELLQALPDYSLGPHYTSRRVSGSPDSLETFHPLPSFSPPRDASTCFLESLVGLSEPVTEVLAPLLESQFEDAALAPLLEPVPV", "length": 583 }, "evidence": [ { "id": "A0A8V1ADP4", "url": "https://omabrowser.org/oma/group/A0A8V1ADP4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96S65-1", "protein_name": "Cysteine/serine-rich nuclear protein 1", "gene_name": "CSRNP1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTGLLKRKFDQLDEDNSSVSSSSSSSGCQSRSCSPSSSVSRAWDSEEEGPWDQMPLPDRDFCGPRSFTPLSILKRARRERPGRVAFDGITVFYFPRCQGFTSVPSRGGCTLGMALRHSACRRFSLAEFAQEQARARHEKLRQRLKEEKLEMLQWKLSAAGVPQAEAGLPPVVDAIDDASVEEDLAVAVAGGRLEEVSFLQPYPARRRRALLRASGVRRIDREEKRELQALRQSREDCGCHCDRICDPETCSCSLAGIKCQMDHTAFPCGCCREGCENPMGRVEFNQARVQTHFIHTLTRLQLEQEAESFRELEAPAQGSPPSPGEEALVPTFPLAKPPMNNELGDNSCSSDMTDSSTASSSASGTSEAPDCPTHPGLPGPGFQPGVDDDSLARILSFSDSDFGGEEEEEEEGSVGNLDNLSCFHPADIFGTSDPGGLASWTHSYSGCSFTSGVLDENANLDASCFLNGGLEGSREGSLPGTSVPPSMDAGRSSSVDLSLSSCDSFELLQALPDYSLGPHYTSQKVSDSLDNIEAPHFPLPGLSPPGDASSCFLESLMGFSEPAAEALDPFIDSQFEDTVPASLMEPVPV", "length": 589 }, "evidence": [ { "id": "A0A8V1ADP4", "url": "https://omabrowser.org/oma/group/A0A8V1ADP4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADP4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADP4" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADP4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADP4" } ], "pmid": "" }, { "name": "sequence-specific DNA binding", "id": "GO:0043565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043565", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADP4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADP4" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADP4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADP4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADP4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADP4" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADP4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADP4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADP4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADP4" } ], "pmid": "" }, { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADP4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADP4" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADP4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADP4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 179, "end_pos": 181, "annotation": "n_glycosylation_sequon" }, { "start_pos": 419, "end_pos": 421, "annotation": "n_glycosylation_sequon" }, { "start_pos": 433, "end_pos": 435, "annotation": "n_glycosylation_sequon" }, { "start_pos": 539, "end_pos": 541, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1ADP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADP4" }, { "id": "PF16019", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16019" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Cysteine/serine-rich nuclear protein N-terminal", "eco_id": "ECO_0000259", "start_pos": 100, "end_pos": 318, "start_aa": "Lys", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 179, "end_pos": 181 }, { "start_pos": 419, "end_pos": 421 }, { "start_pos": 433, "end_pos": 435 }, { "start_pos": 539, "end_pos": 541 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AEC2-1", "uniprot_ac": "A0A8V1AEC2", "uniprot_id": "A0A8V1AEC2_CHICK", "mass": { "chemical_mass": 43154.0, "monoisotopic_mass": 43154.0 }, "refseq": {}, "gene_names": [ { "name": "HDAC11", "type": "recommended", "evidence": [ { "id": "A0A8V1AEC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEC2" } ] } ], "protein_names": [ { "name": "Histone deacetylase 11", "type": "recommended", "evidence": [ { "id": "A0A8V1AEC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEC2/entry#names_and_taxonomy" } ] }, { "name": "3.5.1.98", "type": "synonym", "evidence": [ { "id": "A0A8V1AEC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEC2/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A6N6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6N6#function" }, { "database": "UniProtKB", "id": "ARBA00059784", "url": "https://www.uniprot.org/uniprotkb/ARBA00059784#function" }, { "database": "UniProtKB", "id": "A0A8V1ABI3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABI3#function" }, { "database": "UniProtKB", "id": "A0A8V1AEC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEC2#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEC2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "HDAC11", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEC2", "locus": { "chromosome": "12", "start_pos": 5906310, "end_pos": 5861626, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027988", "url": "https://www.ensembl.org/id/ENSGALG00010027988" } ] } } ], "crossref": [ { "id": "A0A8V1AEC2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AEC2", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd09993", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09993", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "415978", "url": "https://www.ncbi.nlm.nih.gov/gene/415978", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000286", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000286", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023696", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023696", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023801", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023801", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037138", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037138", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044150", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044150", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:415978", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415978", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "EIGFPWS", "url": "https://omabrowser.org/oma/group/EIGFPWS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A6N6", "url": "https://www.orthodb.org/?gene=A0A8V1A6N6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ABI3", "url": "https://www.orthodb.org/?gene=A0A8V1ABI3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AEC2", "url": "https://www.orthodb.org/?gene=A0A8V1AEC2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10625", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10625", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10625:SF23", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10625:SF23", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00850", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00850", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-350054", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-350054", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "58196", "url": "https://www.rhea-db.org/rhea/58196", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1A6N6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6N6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A6N6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6N6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ABI3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABI3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ABI3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABI3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AEC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEC2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AEC2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEC2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLLISLDVSCAMGIRTSMLLVLFYVLGFYLPHRTELYEGVPPTCWPIVYSPDYNITFMGLEKLHPFDAGKWGKVINFLKEEKLIGDDLIVQAREATDEDLLVVHTRRYLNKLKWSFVVATITEIPPVLFLPNFLVQRKVLKPLRTQTGGTIMAGKLAVDRGWAINVGGGFHHCSSDKGGGFCAYADITLAIKFLFERVPGVSKATIIDLDAHQGNGHERDFMNDHRVYIMDAYNRYIYPGDGFAKRAIKRKVELEWGTEDTEYLQKVHTHVEGALNELKPDIIVYNAGTDILDGDPLGGLAISPQGIVKRDEVVFKAARSRGIPILMVTSGGYQKRTARIIADSILNLHNLGLIDKELATSEAESPKVEQMIRDSVTDLTNLTCSDG", "length": 387, "header": "tr|A0A8V1AEC2-1|A0A8V1AEC2_CHICK Isoform 1 of Histone deacetylase 11 OS=Gallus gallus OX=9031 GN=HDAC11 PE=3 SV=1 CANONICAL=A0A8V1AEC2-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A6N6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEC2/entry#A0A8V1A6N6-1", "sequence": { "sequence": "PHRTELYEGVPPTCWPIVYSPDYNITFMGLEKLHPFDAGKWGKVINFLKEEKLIGDDLIVQAREATDEDLLVVHTRRYLNKLKWSFVVATITEIPPVLFLPNFLVQRKVLKPLRTQTGGTIMAGKLAVDRGWAINVGGGFHHCSSDKGGGFCAYADITLAIKFLFERVPGVSKATIIDLDAHQGNGHERDFMNDHRVYIMDAYNRYIYPGDGFAKRAIKRKVELEWGTEDTEYLQKVHTHVEGALNELKPDIIVYNAGTDILDGDPLGGLAISPQGIVKRDEVVFKAARSRGIPILMVTSGGYQKRTARIIADSILNLHNLGLIDKELATSEAESPKVEQMIRDSVTDLTNLTCSDG", "length": 357, "header": "tr|A0A8V1A6N6-1|A0A8V1AEC2_CHICK Computationally mapped isoform of Histone deacetylase 11 OS=Gallus gallus OX=9031 GN=HDAC11 PE=3 SV=1 CANONICAL=A0A8V1AEC2-1" }, "locus": { "chromosome": "12", "start_pos": 5904618, "end_pos": 5881755, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067844.1", "url": "https://www.ensembl.org/id/ENSGALT00010067844.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041587.1", "url": "https://www.ensembl.org/id/ENSGALP00010041587.1" } ] } }, { "isoform_ac": "A0A8V1ABI3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEC2/entry#A0A8V1ABI3-1", "sequence": { "sequence": "MPHRTELYEGVPPTCWPIVYSPDYNITFMGLEKLHPFDAGKWGKVINFLKEEKLIGDDLIVQAREATDEDLLVVHTRRYLNKLKWSFVVATITEIPPVLFLPNFLVQRKVLKPLRTQTGGTIMAGKLAVDRGWAINVGGGFHHCSSDKGGGFCAYADITLAIKFLFERVPGVSKATIIDLDAHQGNGHERDFMNDHRVYIMDAYNRYIYPGDGFAKRAIKRKVELEWGTEDTEYLQKVHTHVEGALNELKPDIIVYNAGTDILDGDPLGGLAISPQGIVKRDEVVFKAARSRGIPILMVTSGGYQKRTARIIADSILNLHNLGLIDKELATSEAESPKVEQMIRDSVTDLTNLTCSDG", "length": 358, "header": "tr|A0A8V1ABI3-1|A0A8V1ABI3_CHICK Computationally mapped isoform of Histone deacetylase 11 OS=Gallus gallus OX=9031 GN=HDAC11 PE=3 SV=1 CANONICAL=A0A8V1AEC2-1" }, "locus": { "chromosome": "12", "start_pos": 5904618, "end_pos": 5880628, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067842.1", "url": "https://www.ensembl.org/id/ENSGALT00010067842.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041585.1", "url": "https://www.ensembl.org/id/ENSGALP00010041585.1" } ] } }, { "isoform_ac": "A0A8V1AEC2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEC2/entry#A0A8V1AEC2-1", "sequence": { "sequence": "MLLISLDVSCAMGIRTSMLLVLFYVLGFYLPHRTELYEGVPPTCWPIVYSPDYNITFMGLEKLHPFDAGKWGKVINFLKEEKLIGDDLIVQAREATDEDLLVVHTRRYLNKLKWSFVVATITEIPPVLFLPNFLVQRKVLKPLRTQTGGTIMAGKLAVDRGWAINVGGGFHHCSSDKGGGFCAYADITLAIKFLFERVPGVSKATIIDLDAHQGNGHERDFMNDHRVYIMDAYNRYIYPGDGFAKRAIKRKVELEWGTEDTEYLQKVHTHVEGALNELKPDIIVYNAGTDILDGDPLGGLAISPQGIVKRDEVVFKAARSRGIPILMVTSGGYQKRTARIIADSILNLHNLGLIDKELATSEAESPKVEQMIRDSVTDLTNLTCSDG", "length": 387, "header": "tr|A0A8V1AEC2-1|A0A8V1AEC2_CHICK Isoform 1 of Histone deacetylase 11 OS=Gallus gallus OX=9031 GN=HDAC11 PE=3 SV=1 CANONICAL=A0A8V1AEC2-1" }, "locus": { "chromosome": "12", "start_pos": 5904618, "end_pos": 5875491, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067843.1", "url": "https://www.ensembl.org/id/ENSGALT00010067843.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041586.1", "url": "https://www.ensembl.org/id/ENSGALP00010041586.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:415978", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415978", "resource": "KEGG Pathway" }, { "id": "R-GGA-350054", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-350054", "resource": "Reactome", "description": "Notch-HLH transcription pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6ALH9-1", "protein_name": "Histone deacetylase 11", "gene_name": "Hdac11", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "PHATQLYQHVPEKRWPIVYSPRYNITFMGLEKLHPFDAGKWGKVINFLKEEKLLSDGMLVEAREASEEDLLVVHTRRYLNELKWSFVVATITEIPPVIFLPNFLVQRKVLRPLRTQTGGTIMAGKLAVERGWAINVGGGFHHCSSDRGGGFCAYADITLAIKFLFERVEGISRATIIDLDAHQGNGHERDFMGDKRVYIMDVYNRHIYPGDRFAKEAIRRKVELEWGTEDEEYLEKVERNVRRSLQEHLPDVVVYNAGTDVLEGDRLGGLSISPAGIVKRDEVVFRVVRAHDIPILMVTSGGYQKRTARIIADSILNLHDLGLIGPEFPYVPARNSSIPLLSRAVP", "length": 346 }, "evidence": [ { "id": "A0A8V1AEC2", "url": "https://omabrowser.org/oma/group/A0A8V1AEC2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "I3LTU6-1", "protein_name": "Histone deacetylase 11", "gene_name": "HDAC11", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPHTTQLYQHVPETRWPIVYSPRYNITFMGLEKLHPFDAGKWGKVISFLKEEKLLTDSMLVEAREASDEDLLVVHTRRYLNELKWSFAVATITEIPPVIFLPNFLVQRKVLKPLRTQTGGTIMAGKLAVERGWAINVGGGFHHCSSDRGGGFCAYADITLAIKFLFERVEGISRATIIDLDAHQGNGHERDFMGDKRVYIMDVYNRHIYPGDRFAKQAIRRKVELEWATEDDEYLTKVERNLEKALQEHRPDVVVYNAGTDVLEGDRLGGLSISPQGIVKRDELVFRMVRSLQVPILMVTSGGYQKRTARIIADSILNLYGLGLIGPESASVSAQNSDSPLLPPEVP", "length": 347 }, "evidence": [ { "id": "A0A8V1AEC2", "url": "https://omabrowser.org/oma/group/A0A8V1AEC2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q91WA3-1", "protein_name": "Histone deacetylase 11", "gene_name": "Hdac11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPHATQLYQHVPEKRWPIVYSPRYNITFMGLEKLHPFDAGKWGKVINFLKEEKLLSDGMLVEAREASEEDLLVVHTRRYLNELKWSFVVATITEIPPVIFLPNFLVQRKVLRPLRTQTGGTIMAGKLAVERGWAINVGGGFHHCSSDRGGGFCAYADITLAIKFLFERVEGISRATIIDLDAHQGNGHERDFMGDKRVYIMDVYNRHIYPGDRFAKEAIRRKVELEWGTEDEEYLEKVERNVRRSLQEHLPDVVVYNAGTDVLEGDRLGGLSISPAGIVKRDEVVFRVVRAHDIPILMVTSGGYQKRTARIIADSILNLHDLGLIGPEFPCVSAQNSGIPLLSCAVP", "length": 347 }, "evidence": [ { "id": "A0A8V1AEC2", "url": "https://omabrowser.org/oma/group/A0A8V1AEC2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q944K3-1", "protein_name": "Histone deacetylase 2", "gene_name": "HDA2", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MTHTRVISTWTELTRDLAIYLLFTFFAIKVFKFLFSCNRTSEISSFSMATHPEALRRERILNSKLYFDVPLSKVSIIYSSSYDISFMGIEKLHPFDSSKWGRVCKFLVSDGFLEEKAIVEPLEASKIDLLVVHSENYLNSLKSSATVARITEVAPVAFFPNFLVQQKVLYPFRKQVGGTILAAKLATERGWAINIGGGFHHCTAERGGGFCAFADISLCIHFAFLRLRISRVMIIDLDAHQGNGHETDLGDDNRVYILDMYNPEIYPFDYRARRFIDQKVEVMSGTTTDEYLRKLDEALEVASRNFQPELVIYNAGTDILDGDPLGLLKISPDGITSRDEKVFRFAREKNIPLVMLTSGGYMKSSARVIADSIENLSRQGLIQTRPE", "length": 387 }, "evidence": [ { "id": "A0A8V1AEC2", "url": "https://omabrowser.org/oma/group/A0A8V1AEC2/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q96DB2-1", "protein_name": "Histone deacetylase 11", "gene_name": "HDAC11", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLHTTQLYQHVPETRWPIVYSPRYNITFMGLEKLHPFDAGKWGKVINFLKEEKLLSDSMLVEAREASEEDLLVVHTRRYLNELKWSFAVATITEIPPVIFLPNFLVQRKVLRPLRTQTGGTIMAGKLAVERGWAINVGGGFHHCSSDRGGGFCAYADITLAIKFLFERVEGISRATIIDLDAHQGNGHERDFMDDKRVYIMDVYNRHIYPGDRFAKQAIRRKVELEWGTEDDEYLDKVERNIKKSLQEHLPDVVVYNAGTDILEGDRLGGLSISPAGIVKRDELVFRMVRGRRVPILMVTSGGYQKRTARIIADSILNLFGLGLIGPESPSVSAQNSDTPLLPPAVP", "length": 347 }, "evidence": [ { "id": "A0A8V1AEC2", "url": "https://omabrowser.org/oma/group/A0A8V1AEC2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VC26-1", "protein_name": "Histone deacetylase 11", "gene_name": "HDAC11", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MKRLTERVHHEEQESEEVVWVKRDDARSAGKLPIVFSRNYAVRFGGLERLHPFDAAKGKHIHKLLCAQLQLDDGSFYEPTELTKDQLRRIHTREYLKSLRWSMNVACIAEVPLMAFVPNRYIQRSYLRPMRFQAAGSILAGKLALDYGWAINLGGGFHHCCSYRGGGFCPYADISLLIVRLFEQEPFRVRRIMIVDLDAHQGNGHERDFNNVAAVYIFDMYNAFVYPRDHVAKESIRCAVELRNYTEDGFYLRQLKRCLMQSLAEFRPDMVVYNAGTDVLEGDPLGNLAISAEGVIERDRLVFSTFRALGIPVVMLLSGGYLKASAGVITDSIVNLRLQGLLN", "length": 343 }, "evidence": [ { "id": "A0A8V1AEC2", "url": "https://omabrowser.org/oma/group/A0A8V1AEC2/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEC2" } ], "pmid": "" }, { "name": "epigenetic regulation of gene expression", "id": "GO:0040029", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0040029", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEC2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "histone deacetylase complex", "id": "GO:0000118", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000118", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEC2" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEC2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "DNA-binding transcription factor binding", "id": "GO:0140297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140297", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEC2" } ], "pmid": "" }, { "name": "histone deacetylase activity, hydrolytic mechanism", "id": "GO:0141221", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0141221", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEC2" } ], "pmid": "" }, { "name": "histone deacetylase activity", "id": "GO:0004407", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004407", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEC2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 381, "end_pos": 383, "annotation": "n_glycosylation_sequon" }, { "start_pos": 54, "end_pos": 56, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "58196", "name": "", "equation": "N(6)-acetyl-L-lysyl-[histone] + H2O = L-lysyl-[histone] + acetate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P83038-1", "A0A8V0XEI5-1", "A0A8V0YJN7-1", "A0A8V0YX55-1", "A0A8V0ZSG8-1", "Q5ZKH6-1", "A0A8V0Y9T3-1", "P56517-1", "P56519-1", "P56520-1", "A0A8V1AEC2-1" ], "evidence": [ { "id": "58196", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/58196" } ] }, { "id": "R-GGA-350058", "name": "Formation of CSL NCOR corepressor complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YJN7-1", "A0A8V0YX55-1", "A0A8V0ZSG8-1", "A0A8V1AEC2-1", "P56517-1", "P83038-1", "A0A8V0Y9T3-1" ], "evidence": [ { "id": "R-GGA-350058", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-350058" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0XEI5", "gene_name": "HDAC9", "activity": [ { "ec_number": "3.5.1.98", "activity": "N(6)-acetyl-L-lysyl-[histone] + H2O = L-lysyl-[histone] + acetate.", "evidence": [ { "id": "A0A8V0XEI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEI5" } ] }, { "ec_number": "3.5.1.98", "activity": "", "evidence": [ { "id": "A0A8V0XEI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEI5" } ] } ] }, { "uniprot_ac": "A0A8V0Y9T3", "gene_name": "HDAC3", "activity": [ { "ec_number": "3.5.1.98", "activity": "N(6)-acetyl-L-lysyl-[histone] + H2O = L-lysyl-[histone] + acetate.", "evidence": [ { "id": "A0A8V0Y9T3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9T3" } ] }, { "ec_number": "3.5.1.98", "activity": "", "evidence": [ { "id": "A0A8V0Y9T3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9T3" } ] } ] }, { "uniprot_ac": "A0A8V0YJN7", "gene_name": "HDAC2", "activity": [ { "ec_number": "3.5.1.98", "activity": "N(6)-acetyl-L-lysyl-[histone] + H2O = L-lysyl-[histone] + acetate.", "evidence": [ { "id": "A0A8V0YJN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJN7" } ] }, { "ec_number": "3.5.1.98", "activity": "", "evidence": [ { "id": "A0A8V0YJN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJN7" } ] } ] }, { "uniprot_ac": "A0A8V0YX55", "gene_name": "HDAC8", "activity": [ { "ec_number": "3.5.1.98", "activity": "N(6)-acetyl-L-lysyl-[histone] + H2O = L-lysyl-[histone] + acetate.", "evidence": [ { "id": "A0A8V0YX55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YX55" } ] }, { "ec_number": "3.5.1.98", "activity": "", "evidence": [ { "id": "A0A8V0YX55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YX55" } ] } ] }, { "uniprot_ac": "A0A8V0ZSG8", "gene_name": "HDAC7", "activity": [ { "ec_number": "3.5.1.98", "activity": "N(6)-acetyl-L-lysyl-[histone] + H2O = L-lysyl-[histone] + acetate.", "evidence": [ { "id": "A0A8V0ZSG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSG8" } ] }, { "ec_number": "3.5.1.98", "activity": "", "evidence": [ { "id": "A0A8V0ZSG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSG8" } ] } ] }, { "uniprot_ac": "A0A8V1AEC2", "gene_name": "HDAC11", "activity": [ { "ec_number": "3.5.1.98", "activity": "N(6)-acetyl-L-lysyl-[histone] + H2O = L-lysyl-[histone] + acetate.", "evidence": [ { "id": "A0A8V1AEC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEC2" } ] }, { "ec_number": "3.5.1.98", "activity": "", "evidence": [ { "id": "A0A8V1AEC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEC2" } ] } ] }, { "uniprot_ac": "P56517", "gene_name": "HDAC1", "activity": [ { "ec_number": "3.5.1.-", "activity": "", "evidence": [ { "id": "P56517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P56517" } ] }, { "ec_number": "3.5.1.98", "activity": "N(6)-acetyl-L-lysyl-[histone] + H2O = L-lysyl-[histone] + acetate.", "evidence": [ { "id": "P56517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P56517" } ] }, { "ec_number": "3.5.1.98", "activity": "", "evidence": [ { "id": "P56517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P56517" } ] } ] }, { "uniprot_ac": "P56519", "gene_name": "HDAC2", "activity": [ { "ec_number": "3.5.1.-", "activity": "", "evidence": [ { "id": "P56519", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P56519" } ] }, { "ec_number": "3.5.1.98", "activity": "N(6)-acetyl-L-lysyl-[histone] + H2O = L-lysyl-[histone] + acetate.", "evidence": [ { "id": "P56519", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P56519" } ] }, { "ec_number": "3.5.1.98", "activity": "", "evidence": [ { "id": "P56519", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P56519" } ] } ] }, { "uniprot_ac": "P56520", "gene_name": "HDAC3", "activity": [ { "ec_number": "3.5.1.-", "activity": "", "evidence": [ { "id": "P56520", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P56520" } ] }, { "ec_number": "3.5.1.98", "activity": "N(6)-acetyl-L-lysyl-[histone] + H2O = L-lysyl-[histone] + acetate.", "evidence": [ { "id": "P56520", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P56520" } ] }, { "ec_number": "3.5.1.98", "activity": "", "evidence": [ { "id": "P56520", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P56520" } ] } ] }, { "uniprot_ac": "P83038", "gene_name": "HDAC4", "activity": [ { "ec_number": "3.5.1.98", "activity": "N(6)-acetyl-L-lysyl-[histone] + H2O = L-lysyl-[histone] + acetate.", "evidence": [ { "id": "P83038", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P83038" } ] }, { "ec_number": "3.5.1.98", "activity": "", "evidence": [ { "id": "P83038", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P83038" } ] } ] }, { "uniprot_ac": "Q5ZKH6", "gene_name": "hdac9", "activity": [ { "ec_number": "3.5.1.98", "activity": "N(6)-acetyl-L-lysyl-[histone] + H2O = L-lysyl-[histone] + acetate.", "evidence": [ { "id": "Q5ZKH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKH6" } ] }, { "ec_number": "3.5.1.98", "activity": "", "evidence": [ { "id": "Q5ZKH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKH6" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AEC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEC2" }, { "id": "PF00850", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00850" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Histone deacetylase", "eco_id": "ECO_0000259", "start_pos": 64, "end_pos": 345, "start_aa": "His", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.5.1.98", "ec_name": "N(6)-acetyl-L-lysyl-[histone] + H2O = L-lysyl-[histone] + acetate.", "evidence": [ { "id": "3.5.1.98", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.1.98" }, { "id": "3.5.1.98", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.5.1.98" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 381, "end_pos": 383 }, { "start_pos": 54, "end_pos": 56 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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{ "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AEG4-1", "uniprot_ac": "A0A8V1AEG4", "uniprot_id": "A0A8V1AEG4_CHICK", "mass": { "chemical_mass": 165480.0, "monoisotopic_mass": 165480.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "RanBD1 domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8V1AEG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEG4/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEG4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEG4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEG4", "locus": {} } ], "crossref": [ { "id": "IPR000156", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000156", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013105", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013105", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019734", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019734", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045255", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045255", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR23138", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23138", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23138:SF87", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23138:SF87", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00638", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00638", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07719", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07719", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1A6S4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6S4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A6S4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6S4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A6S9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6S9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A6S9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6S9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ABM1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABM1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ABM1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABM1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AEG4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEG4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AEG4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEG4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLRRTKAEVERYVASVQAAASSPRERSLKGFFFAKLYFGIKEYELAQRHLSIYLHVRERDPKAHRFLGQIYEAQDNVEKACGCYERSVELNPMQKDLVLKIAELLSNHNITDERAKYWVEKAARLFPGNPAAYRLKEQLLERKGEAGWNQLLDMIRTELCARPDDLYLNIRLVALYRSNNKLRDAVLHCQEVEKKIPVDSSLEWCLCVIKTFEEYLESVRDLESDRNNWRAIKKDHLLAYSSLVKMTLASRDVQESRGALESFDRVLHSVKLCVNGPDELSRAFLEMKGHFYMHAGTFLLKMAQNSEAQWRDACELAALCYLKSFHIPKPKSKPVKGDGTGQDLLEMLACDRKSQSGHMLLNLSHSKEDFLKKIVENFANKRGLFTLFESLFGSGASKERSFLGTDDIGDVSTQAPVQEELSEYDIGAVRMHSGSLQHLVWLGLQWNSMSVLFPLRKLLERLFHLPQETSKLETDAPDSICLLDLEVFLLGMVFTGNLELQEKLNTRCGTHQPPFLPLLLCKQYCTEKQRSWWDAVCTLMQKKTIPDSVTKLRLLVQHGLSTLRALEKHGLQPALIMHWARSLQKTGISLNSFCDQKQYIGRSVYYWKKTLLSLKTIKKHKSIPEPTDPLFKHFRSVDIQVAAYEEEAHIAFATLDAVEGKTDDALLAFEAIKNVVSYWNLAILCQRKAKEIENDAMLPEQREEHKTYLLKRKHYLMKVIDESSCDPSVANKLPVSVKTVTEMLNAVIQELGENEEEESLASGNISQAAGLEVKYSTPSPKRLSFSPANNYKFSPKTLPQWAEDQKSLLQMLSQQVEALKNEIQEMKRNRSGVSISSHGWPGESYGTDTVSAGYERAQNLHEVPVTVATSGPSVDYSRSPAYNSRHLLRTSATNVTPTKVRTNVSAQAVPANFLKTTGFDSVCNSETAVKKRSGRLSPSNEEEGREVWQGMSENTTATFLDAADESFVSEEASSCSGSCKTGRQVVKLRANHRTAADRNMRPVKGSDRAWVWTACNFGDRGRKVELLAVRFKRQDVAGSFKQTCDEAKQAHETGTLITPRVSRTNTARASPCGKDAVAGLEGTGRVAADLSLGDALWSTSETPQKPVVSPAKFVFQAESVKSVFSSEKTFPFGNTSAPSSLFGFGVHPPRKSAASQKAEQEKPGAAEPPKSCGAPQKPLEGKASQLAPAAQDGCKTGRQVVKLRANHRTAADRNMRPVKGSDRAWVWTACNFGDRGRKVELLAVRFKRQDVAGSFKQTCDEAKQAHETGTLITPRVSRTNTARASPCGKDAVAGLEGTGRVAADLSLGDAASDAAAEASELWSTSETPQKPVVSPAKFVFQAESVKSVFSSEKTFPFGNTSAPSSLFGFGVHPPRKSAASQKAEQEKPGAAEPPKSCGAPQKPLEGKASQLAPAAQDGPSNFSFKILEKETKRETFQLPCLVLLFLLFLLYTENVLMGFSFPGVGSSLSDKTSSLLTHCVHPWHCFCGKL", "length": 1490, "header": "tr|A0A8V1AEG4-1|A0A8V1AEG4_CHICK Isoform 1 of RanBD1 domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1AEG4-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A6S4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEG4/entry#A0A8V1A6S4-1", "sequence": { "sequence": "MLRRTKAEVERYVASVQAAASSPRERSLKGFFFAKLYFGIKEYELAQRHLSIYLHVRERDPKAHRFLGQIYEAQDNVEKACGCYERSVELNPMQKDLVLKIAELLSNHNITDERAKYWVEKAARLFPGNPAAYRLKEQLLERKGEAGWNQLLDMIRTELCARPDDLYLNIRLVALYRSNNKLRDAVLHCQEVEKKIPVDSSLEWCLCVIKTFEEYLESVRDLESDRNNWRAIKKDHLLAYSSLVKMTLASRDVQESRGALESFDRVLHSVKLCVNGPDELSRAFLEMKGHFYMHAGTFLLKMAQNSEAQWRDACELAALCYLKSFHIPKPKSKPVKGDGTGQDLLEMLACDRKSQSGHMLLNLSHSKEDFLKKIVENFANKRGLFTLFESLFGSGASKERSFLGTDDIGDVSTQAPVQEELSEYDIGAVRMHSGSLQHLVWLGLQWNSMSVLFPLRKLLERLFHLPQETSKLETDAPDSICLLDLEVFLLGMVFTGNLELQEKLNTRCGTHQPPFLPLLLCKQYCTEKQRSWWDAVCTLMQKKTIPDSVTKLRLLVQHGLSTLRALEKHGLQPALIMHWARSLQKTGISLNSFCDQKQYIGRSVYYWKKTLLSLKTIKKHKSIPEPTDPLFKHFRSVDIQVAAYEEEAHIAFATLDAVEGKTDDALLAFEAIKNVVSYWNLAILCQRKAKEIENDAMLPEQREEHKTYLLKRKHYLMKVIDESSCDPSVANKLPVSVKTVTEMLNAVIQELGENEEEESLASGNISQAAGLEVKYSTPSPKRLSFSPANNYKFSPKTLPQWAEDQKSLLQMLSQQVEALKNEIQEMKRNRSGVSISSHGWPGESYGTDTVSAGYERAQNLHEAVLRQLPSPHFHVEREPY", "length": 880, "header": "tr|A0A8V1A6S4-1|A0A8V1AEG4_CHICK Computationally mapped isoform of RanBD1 domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1AEG4-1" }, "locus": { "chromosome": "12", "start_pos": 166651, "end_pos": 153573, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067879.1", "url": "https://www.ensembl.org/id/ENSGALT00010067879.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041622.1", "url": "https://www.ensembl.org/id/ENSGALP00010041622.1" } ] } }, { "isoform_ac": "A0A8V1A6S9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEG4/entry#A0A8V1A6S9-1", "sequence": { "sequence": "MLRRTKAEVERYVASVQAAASSPRERSLKGFFFAKLYFGIKEYELAQRHLSIYLHVRERDPKAHRFLGQIYEAQDNVEKACGCYERSVELNPMQKDLVLKIAELLSNHNITDERAKYWVEKAARLFPGNPAAYRLKEQLLERKGEAGWNQLLDMIRTELCARPDDLYLNIRLVALYRSNNKLRDAVLHCQEVEKKIPVDSSLEWCLCVIKTFEEYLESVRDLESDRNNWRAIKKDHLLAYSSLVKMTLASRDVQESRGALESFDRVLHSVKLCVNGPDELSRAFLEMKGHFYMHAGTFLLKMAQNSEAQWRDACELAALCYLKSFHIPKPKSKPVKGDGTGQDLLEMLACDRKSQSGHMLLNLSHSKEDFLKKIVENFANKRGLFTLFESLFGSGASKERSFLGTDDIGDVSTQAPVQEELSEYDIGAVRMHSGSLQHLVWLGLQWNSMSVLFPLRKLLERLFHLPQETSKLETDAPDSICLLDLEVFLLGMVFTGNLELQEKLNTRCGTHQPPFLPLLLCKQYCTEKQRSWWDAVCTLMQKKTIPDSVTKLRLLVQHGLSTLRALEKHGLQPALIMHWARSLQKTGISLNSFCDQKQYIGRSVYYWKKTLLSLKTIKKHKSIPEPTDPLFKHFRSVDIQVAAYEEEAHIAFATLDAVEGKTDDALLAFEAIKNVVSYWNLAILCQRKAKEIENDAMLPEQREEHKTYLLKRKHYLMKVIDESSCDPSVANKLPVSVKTVTEMLNAVIQELGENEEEESLASGNISQAAGLEVKYSTPSPKRLSFSPANNYKFSPKTLPQWAEDQKSLLQMLSQQVEALKNEIQEMKRNRSGVSISSHGWPGESYGTDTVSAGYERAQNLHEVPVTVATSGPSVDYSRSPAYNSRHLLRTSATNVTPTKVRTNVSAQAVPANFLKTTGFDSLLYQCVCKVLRKPIKSSLGFHPQHSDLLFRKLIVHPLWISCSGSCKTGRQVVKLRANHRTAADRNMRPVKGSDRAWVWTACNFGDRGRKVELLAVRFKRQDVAGSFKQTCDEAKQLWSTSETPQKPVVSPAKFVFQAESVKSVFSSEKTFPFGNTSAPSSLFGFGVHPPRKSAASQKAEQEKPGAAEPPKSCGAPQKPLEGKASQLEASSCSGSCKTGRQVVKLRANHRTAADRNMRPVKGSDRAWVWTACNFGDRGRKVELLAVRFKRQDVAGSFKQTCDEAKQAHETGTLITPRVSRTNTARASPCGKDAVAGLEGTGRVAADLSLGDAASDAAAEASELWSTSETPQKPVVSPAKFVFQAESVKSVFSSEKTFPFGNTSAPSSLFGFGVHPPRKSAASQKAEQEKPGAAEPPKSCGAPQKPLEGKASQLAPAAQDGPSNFSFKILEKEIKETKRETFQLPCLVLLFLLFLLYTENVLMGFSFPGVGSSLSDKTSSLLTHCVHPWHCFCGKL", "length": 1435, "header": "tr|A0A8V1A6S9-1|A0A8V1AEG4_CHICK Computationally mapped isoform of RanBD1 domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1AEG4-1" }, "locus": { "chromosome": "12", "start_pos": 166651, "end_pos": 146544, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067884.1", "url": "https://www.ensembl.org/id/ENSGALT00010067884.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041627.1", "url": "https://www.ensembl.org/id/ENSGALP00010041627.1" } ] } }, { "isoform_ac": "A0A8V1ABM1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEG4/entry#A0A8V1ABM1-1", "sequence": { "sequence": "RSLKGFFFAKLYFGIKEYELAQRHLSIYLHVRERDPKAHRFLGQIYEAQDNVEKACGCYERSVELNPMQKDLVLKIAELLSNHNITDERAKYWVEKAARLFPGNPAAYRLKEQLLERKGEAGWNQLLDMIRTELCARPDDLYLNIRLVALYRSNNKLRDAVLHCQEVEKKIPVDSSLEWCLCVIKTFEEYLESVRDLESDRNNWRAIKKDHLLAYSSLVKMTLASRDVQESRGALESFDRVLHSVKLCVNGPDELSRAFLEMKGHFYMHAGTFLLKMAQNSEAQWRDACELAALCYLKSFHIPKPKSKPVKGDGTGQDLLEMLACDRKSQSGHMLLNLSHSKEDFLKKIVENFANKRGLFTLFESLFGSGASKERSFLGTDDIGDVSTQAPVQEELSEYDIGAVRMHSGSLQHLVWLGLQWNSMSVLFPLRKLLERLFHLPQETSKLETDAPDSICLLDLEVFLLGMVFTGNLELQEKLNTRCGTHQPPFLPLLLCKQYCTEKQRSWWDAVCTLMQKKTIPDSVTKLRLLVQHGLSTLRALEKHGLQPALIMHWARSLQKTGISLNSFCDQKQYIGRSVYYWKKTLLSLKTIKKHKSIPEPTDPLFKHFRSVDIQVAAYEEEAHIAFATLDAVEGKTDDALLAFEAIKNVVSYWNLAILCQRKAKEIENDAMLPEQREEHKTYLLKRKHYLMKVIDESSCDPSVANKLPVSVKTVTEMLNAVIQELGENEEEESLASGNISQAAGLEVKYSTPSPKRLSFSPANNYKFSPKTLPQWAEDQKSLLQMLSQQVENEIQEMKRNRSGVSISSHGWPGESYGTDTVSAGYERAQNLHEVPVTVATSGPSVDYSRSPAYNSRHLLRTSATNVTPTKVRTNVSAQAVPANFLKTTGFDSTGRKIHYQLIFGIQGLGEKASKALSEEASSCSGSCKTGRQVVKLRANHRTAADRNMRPVKGSDRAWVWTACNFGDRGRKVELLAVRFKRQDVAGSFKQTCDEAKQLWSTSETPQKPVVSPAKFVFQAESVKSVFSSEKTFPFGNTSAPSSLFGFGVHPPRKSAASQKAEQEKPGAAEPPKSCGAPQKPLEVSEEASSCSGSCKTGRQVVKLRANHRTAADRNMRPVKGSDRAWVWTACNFGDRGRKVELLAVRFKRQDVAGSFKQTCDEAKQAHETGTLITPRVSRTNTARASPCGKDAVAGLEGTGRVAADLSLGDAASDAAAEASELWSTSETPQKPVVSPAKFVFQAESVKSVFSSEKTFPFGNTSAPSSLFGFGVHPPRKSAASQKAEQEKPGAAEPPKSCGAPQKPLEVGSSLSDKTSSLLTHCVHPWHCFCGKL", "length": 1333, "header": "tr|A0A8V1ABM1-1|A0A8V1ABM1_CHICK Computationally mapped isoform of RanBD1 domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1AEG4-1" }, "locus": { "chromosome": "12", "start_pos": 164951, "end_pos": 146544, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067881.1", "url": "https://www.ensembl.org/id/ENSGALT00010067881.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041624.1", "url": "https://www.ensembl.org/id/ENSGALP00010041624.1" } ] } }, { "isoform_ac": "A0A8V1AEG4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEG4/entry#A0A8V1AEG4-1", "sequence": { "sequence": "MLRRTKAEVERYVASVQAAASSPRERSLKGFFFAKLYFGIKEYELAQRHLSIYLHVRERDPKAHRFLGQIYEAQDNVEKACGCYERSVELNPMQKDLVLKIAELLSNHNITDERAKYWVEKAARLFPGNPAAYRLKEQLLERKGEAGWNQLLDMIRTELCARPDDLYLNIRLVALYRSNNKLRDAVLHCQEVEKKIPVDSSLEWCLCVIKTFEEYLESVRDLESDRNNWRAIKKDHLLAYSSLVKMTLASRDVQESRGALESFDRVLHSVKLCVNGPDELSRAFLEMKGHFYMHAGTFLLKMAQNSEAQWRDACELAALCYLKSFHIPKPKSKPVKGDGTGQDLLEMLACDRKSQSGHMLLNLSHSKEDFLKKIVENFANKRGLFTLFESLFGSGASKERSFLGTDDIGDVSTQAPVQEELSEYDIGAVRMHSGSLQHLVWLGLQWNSMSVLFPLRKLLERLFHLPQETSKLETDAPDSICLLDLEVFLLGMVFTGNLELQEKLNTRCGTHQPPFLPLLLCKQYCTEKQRSWWDAVCTLMQKKTIPDSVTKLRLLVQHGLSTLRALEKHGLQPALIMHWARSLQKTGISLNSFCDQKQYIGRSVYYWKKTLLSLKTIKKHKSIPEPTDPLFKHFRSVDIQVAAYEEEAHIAFATLDAVEGKTDDALLAFEAIKNVVSYWNLAILCQRKAKEIENDAMLPEQREEHKTYLLKRKHYLMKVIDESSCDPSVANKLPVSVKTVTEMLNAVIQELGENEEEESLASGNISQAAGLEVKYSTPSPKRLSFSPANNYKFSPKTLPQWAEDQKSLLQMLSQQVEALKNEIQEMKRNRSGVSISSHGWPGESYGTDTVSAGYERAQNLHEVPVTVATSGPSVDYSRSPAYNSRHLLRTSATNVTPTKVRTNVSAQAVPANFLKTTGFDSVCNSETAVKKRSGRLSPSNEEEGREVWQGMSENTTATFLDAADESFVSEEASSCSGSCKTGRQVVKLRANHRTAADRNMRPVKGSDRAWVWTACNFGDRGRKVELLAVRFKRQDVAGSFKQTCDEAKQAHETGTLITPRVSRTNTARASPCGKDAVAGLEGTGRVAADLSLGDALWSTSETPQKPVVSPAKFVFQAESVKSVFSSEKTFPFGNTSAPSSLFGFGVHPPRKSAASQKAEQEKPGAAEPPKSCGAPQKPLEGKASQLAPAAQDGCKTGRQVVKLRANHRTAADRNMRPVKGSDRAWVWTACNFGDRGRKVELLAVRFKRQDVAGSFKQTCDEAKQAHETGTLITPRVSRTNTARASPCGKDAVAGLEGTGRVAADLSLGDAASDAAAEASELWSTSETPQKPVVSPAKFVFQAESVKSVFSSEKTFPFGNTSAPSSLFGFGVHPPRKSAASQKAEQEKPGAAEPPKSCGAPQKPLEGKASQLAPAAQDGPSNFSFKILEKETKRETFQLPCLVLLFLLFLLYTENVLMGFSFPGVGSSLSDKTSSLLTHCVHPWHCFCGKL", "length": 1490, "header": "tr|A0A8V1AEG4-1|A0A8V1AEG4_CHICK Isoform 1 of RanBD1 domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1AEG4-1" }, "locus": { "chromosome": "12", "start_pos": 166651, "end_pos": 146544, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067883.1", "url": "https://www.ensembl.org/id/ENSGALT00010067883.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041626.1", "url": "https://www.ensembl.org/id/ENSGALP00010041626.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 109, "end_pos": 111, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1134, "end_pos": 1136, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1359, "end_pos": 1361, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1421, "end_pos": 1423, "annotation": "n_glycosylation_sequon" }, { "start_pos": 362, "end_pos": 364, "annotation": "n_glycosylation_sequon" }, { "start_pos": 764, "end_pos": 766, "annotation": "n_glycosylation_sequon" }, { "start_pos": 829, "end_pos": 831, "annotation": "n_glycosylation_sequon" }, { "start_pos": 894, "end_pos": 896, "annotation": "n_glycosylation_sequon" }, { "start_pos": 903, "end_pos": 905, "annotation": "n_glycosylation_sequon" }, { "start_pos": 954, "end_pos": 956, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AEG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEG4" }, { "id": "PS50196", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50196" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RanBD1", "eco_id": "ECO_0000259", "start_pos": 984, "end_pos": 1053, "start_aa": "Gln", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 109, "end_pos": 111 }, { "start_pos": 1134, "end_pos": 1136 }, { "start_pos": 1359, "end_pos": 1361 }, { "start_pos": 1421, "end_pos": 1423 }, { "start_pos": 362, "end_pos": 364 }, { "start_pos": 764, "end_pos": 766 }, { "start_pos": 829, "end_pos": 831 }, { "start_pos": 894, "end_pos": 896 }, { "start_pos": 903, "end_pos": 905 }, { "start_pos": 954, "end_pos": 956 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AEA4-1", "uniprot_ac": "A0A8V1AEA4", "uniprot_id": "A0A8V1AEA4_CHICK", "mass": { "chemical_mass": 61729.0, "monoisotopic_mass": 61729.0 }, "refseq": { "ac": "XP_004934999", "name": "solute carrier family 45 member 3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004934999" }, "gene_names": [ { "name": "SLC45A3", "type": "recommended", "evidence": [ { "id": "A0A8V1AEA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEA4" } ] }, { "name": "SLC45A3", "type": "synonym", "evidence": [ { "id": "XP_004934999", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004934999" } ] } ], "protein_names": [ { "name": "Solute carrier family 45 member 3", "type": "synonym", "evidence": [ { "id": "A0A8V1AEA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEA4/entry#names_and_taxonomy" } ] }, { "name": "solute carrier family 45 member 3", "type": "synonym", "evidence": [ { "id": "XP_004934999", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004934999" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052557.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004934999.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004934999", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004934999" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEA4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEA4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SLC45A3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEA4", "locus": { "chromosome": "26", "start_pos": 2262159, "end_pos": 2271755, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027026", "url": "https://www.ensembl.org/id/ENSGALG00010027026" } ] } } ], "crossref": [ { "id": "A0A8V1AEA4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AEA4", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd17313", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17313", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "771751", "url": "https://www.ncbi.nlm.nih.gov/gene/771751", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011701", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011701", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036259", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036259", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:771751", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:771751", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FQWYALF", "url": "https://omabrowser.org/oma/group/FQWYALF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A6U1", "url": "https://www.orthodb.org/?gene=A0A8V1A6U1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AEA4", "url": "https://www.orthodb.org/?gene=A0A8V1AEA4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19432", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19432", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19432:SF37", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19432:SF37", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07690", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07690", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-189200", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-189200", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_004934999", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004934999", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1A6U1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6U1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A6U1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6U1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AEA4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEA4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AEA4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEA4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MALSVLLRNRRAQLLLLNSLTFGLEVCLAAGITYVPPLLLEVGVEEKFMTMVLGIGPVLGLVFVPLIGSASDHWHSSYGRRRPFIWVLCLGVLLSLFIIPHASSLASLFALNARPLEIAFLILGIGMLDFCGQVCFTPLEALLSDLFQEPDNCRQAFSMYAFMISLGGCIGYLLPAIDWGASFLAPYLGGQETCLFSLLAVIFLGCVLATLFVTEEAAAQVDALDGPVLKDALPNPSPSACCSCQLSRSLLQARHVMQALRNLCTLVPRLHSLYCRIPKVIRRLFVAELCSWMALMTFMLFYTDFVGEGLYLGVPRAKPGTDARRRYDEGVRMGSLGLFLQCVTSIFFSTIMDRMVKQFGTRAVYLASVVFFPAAAFVMCLSHSVIVVTISAALTGFTFSALQILPYTLASLYHHEKQVFLHKYKSKEEKDAARSDKKSAFPKGHLSNQKLPYQNGHAGGLYSSSSSSSSPPAASSALCGSSSCDVSLMMMVGESDSVPPGRGICLDLAILDSAFLLSQVVPSLFMGSIVQFTQSVTAYMVSAAGLGLVAIYFATKVVFDKSDMAKYSV", "length": 569, "header": "tr|A0A8V1AEA4-1|A0A8V1AEA4_CHICK Isoform 1 of Solute carrier family 45 member 3 OS=Gallus gallus OX=9031 GN=SLC45A3 PE=3 SV=1 CANONICAL=A0A8V1AEA4-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A6U1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEA4/entry#A0A8V1A6U1-1", "sequence": { "sequence": "MLKMGDGIRPSGIGPVLGLVFVPLIGSASDHWHSSYGRRRPFIWVLCLGVLLSLFIIPHASSLASLFALNARPLEIAFLILGIGMLDFCGQVCFTPLEALLSDLFQEPDNCRQAFSMYAFMISLGGCIGYLLPAIDWGASFLAPYLGGQETCLFSLLAVIFLGCVLATLFVTEEAAAQVDALDGPVLKDALPNPSPSACCSCQLSRSLLQARHVMQALRNLCTLVPRLHSLYCRIPKVIRRLFVAELCSWMALMTFMLFYTDFVGEGLYLGVPRAKPGTDARRRYDEGVRMGSLGLFLQCVTSIFFSTIMDRMVKQFGTRAVYLASVVFFPAAAFVMCLSHSVIVVTISAALTGFTFSALQILPYTLASLYHHEKQVFLHKYKSKEEKDAARSDKKSAFPKGHLSNQKLPYQNGHAGGLYSSSSSSSSPPAASSALCGSSSCDVSLMMMVGESDSVPPGRGICLDLAILDSAFLLSQVVPSLFMGSIVQFTQSVTAYMVSAAGLGLVAIYFATKVVFDKSDMAKYSV", "length": 527, "header": "tr|A0A8V1A6U1-1|A0A8V1AEA4_CHICK Computationally mapped isoform of Solute carrier family 45 member 3 OS=Gallus gallus OX=9031 GN=SLC45A3 PE=3 SV=1 CANONICAL=A0A8V1AEA4-1" }, "locus": { "chromosome": "26", "start_pos": 2269037, "end_pos": 2263163, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065496.1", "url": "https://www.ensembl.org/id/ENSGALT00010065496.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039834.1", "url": "https://www.ensembl.org/id/ENSGALP00010039834.1" } ] } }, { "isoform_ac": "A0A8V1AEA4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEA4/entry#A0A8V1AEA4-1", "sequence": { "sequence": "MALSVLLRNRRAQLLLLNSLTFGLEVCLAAGITYVPPLLLEVGVEEKFMTMVLGIGPVLGLVFVPLIGSASDHWHSSYGRRRPFIWVLCLGVLLSLFIIPHASSLASLFALNARPLEIAFLILGIGMLDFCGQVCFTPLEALLSDLFQEPDNCRQAFSMYAFMISLGGCIGYLLPAIDWGASFLAPYLGGQETCLFSLLAVIFLGCVLATLFVTEEAAAQVDALDGPVLKDALPNPSPSACCSCQLSRSLLQARHVMQALRNLCTLVPRLHSLYCRIPKVIRRLFVAELCSWMALMTFMLFYTDFVGEGLYLGVPRAKPGTDARRRYDEGVRMGSLGLFLQCVTSIFFSTIMDRMVKQFGTRAVYLASVVFFPAAAFVMCLSHSVIVVTISAALTGFTFSALQILPYTLASLYHHEKQVFLHKYKSKEEKDAARSDKKSAFPKGHLSNQKLPYQNGHAGGLYSSSSSSSSPPAASSALCGSSSCDVSLMMMVGESDSVPPGRGICLDLAILDSAFLLSQVVPSLFMGSIVQFTQSVTAYMVSAAGLGLVAIYFATKVVFDKSDMAKYSV", "length": 569, "header": "tr|A0A8V1AEA4-1|A0A8V1AEA4_CHICK Isoform 1 of Solute carrier family 45 member 3 OS=Gallus gallus OX=9031 GN=SLC45A3 PE=3 SV=1 CANONICAL=A0A8V1AEA4-1" }, "locus": { "chromosome": "26", "start_pos": 2268918, "end_pos": 2263163, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065492.1", "url": "https://www.ensembl.org/id/ENSGALT00010065492.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039833.1", "url": "https://www.ensembl.org/id/ENSGALP00010039833.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:771751", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:771751", "resource": "KEGG Pathway" }, { "id": "R-GGA-189200", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-189200", "resource": "Reactome", "description": "Cellular hexose transport" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287AF62-1", "protein_name": "Solute carrier family 45 member 3", "gene_name": "SLC45A3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEGWQKWVPGRVLGSWWQQGGEAGASGARPSWSSSEVHERARALPTRPIMVQRLWMSRLLRHRKAQLLLVNLLTFGLEVCLAAGITYVPPLLLEVGVEEKFMTMVLGIGPVLGLVSVPLLGSASDHWRGRYGRRRPFIWALSLGVLLSLFLIPRAGRLAGLLCPDTRPLELALLILGVGLLDFCGQVCFTPLEALLSDLFRDPDHCRQAFSVYAFMISLGGCLGYLLPAIDWDASALAPYLGTQEECLFGLLSLIFLTCVTATLFVAEEAALGPAEPAEGLSVPSMPSYCCPCRARLAFRNLGALFPRLHQLCCRMPRTLRRLFVAELCSWMAFMTFTLFYTDFVGEGLYQGVPRAEPGTEARRHYDEGVRMGSLGLFLQCAISLLFSLVMDRLVQRFGTRAVYLASVVAFPVAAGATCLSRSVAVVTASAALTGFTFSALQILPYTLASLYHREKQVFLPKYRGDDGAGASEDSLMTSFPPGPKAASPFPNGHIGAGGSSLLASPPTLCGTSACDVSMRAVVGEPPEARVVPGRGICLDLAILDSAFLLSQVAPSLFMGSIVQLSESVTAYMVSAAGLGLVAIYFVTQVVFDKSDLAKYSV", "length": 602 }, "evidence": [ { "id": "A0A8V1AEA4", "url": "https://omabrowser.org/oma/group/A0A8V1AEA4/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "D3ZPP5-1", "protein_name": "Solute carrier family 45, member 3", "gene_name": "Slc45a3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAPGPLTALSIMIQRLWASRLLRHRKAQLLLVNLLTFGLEVCLAAGITYVPPLLLEVGVEEKFMTMVLGIGPVLGLVSVPLLGSASDQWRGRYGRRRPFIWALSLGVLLSLFLIPRAGWLAGLLCSDTRPLELALLILGVGLLDFCGQVCFTPLEALLSDLFRDPDHCRQAFSVYAFMISLGGCLGYLLPAIDWDTSALAPYLGTQEECLFGLLTLIFLICVAATLLVAEEAVLGPPEPAEGLLVSSVSRRCCSCHAGLAFRNLGTLFPRLHQLCCRMPRTLRRLFVAELCSWMALMTFTLFYTDFVGEGLYQGVPRAEPGTEARRHYDEGIRMGSLGLFLQCAISLFFSLVMDRLVQKFGTRSVYLASVMTFPVAAAATCLSHSVVVVTASAALTGFTFSALQILPYTLASLYHREKQVFLPKYRGDAGGGSSEDSQTTSFLLGPKPGAPFPNGHVGPGGSSILVPPPALCGASACDVSMRVVVGEPPEAKVVTGRGICLDLAILDSAFLLSQVAPSLFMGSIVQLSHSVTAYMVSAAGLGLVAIYFATQVVFDKNDLAKYSL", "length": 564 }, "evidence": [ { "id": "A0A8V1AEA4", "url": "https://omabrowser.org/oma/group/A0A8V1AEA4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1BMB9-1", "protein_name": "Solute carrier family 45 member 3", "gene_name": "SLC45A3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MVQRLWAGRLLRHRKAQLLLVNLLTFGLEVCLAAGITYVPPLLLEVGVEEKFMTMVLGIGPVLGLFSVPLLGSASDHWRGRYGRRRPFIWALSLGVLLSLFLIPRASWLAGLLCPDARPLELALLILGVGLLAFCGQLCFTPLEALLSDLFRDPDHCRQAFSVYAFMIGLGGCLGYLLPAIDWDASALAPYLGTQEECLFGLLALIFLTCVAATAFVAEEAALGPAEPAEGLSAPSVPPCCPGRARLALRSLGALCPWLRRLCCRTPRALRRLFVAELCSWMAFMTFTLFYTDFVGEGLYQGVPGAEPGTEARRHYDEGVRMGSLGLFLQCAISLLFSLVMDRLVQRFGTRAVYLASVVAFPVAAGATCLSRSVAVVTASAALTGVTFSALQILPYTLASLYHREKQVFLPKYRGDDGGGAGEDGVMTSFLPGPKAASPFPHGHGGPGGLLAAPPALCGASACEGSVRTAVAEPPEARAIPGRGICLDLAILDSAFLLSQVAPSLFMGFIVQLSQSVTAYMVSAAGLGLVAIYFVTQVVFDKSDLAKYSV", "length": 550 }, "evidence": [ { "id": "A0A8V1AEA4", "url": "https://omabrowser.org/oma/group/A0A8V1AEA4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8K0H7-1", "protein_name": "Solute carrier family 45 member 3", "gene_name": "Slc45a3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIQRLWASRLLRHRKAQLLLVNLLTFGLEVCLAAGITYVPPLLLEVGVEEKFMTMVLGIGPVLGLVSVPLLGSASDQWRGRYGRRRPFIWALSLGVLLSLFLIPRAGWLAGLLYPDTRPLELALLILGVGLLDFCGQVCFTPLEALLSDLFRDPDHCRQAFSVYAFMISLGGCLGYLLPAIDWDTSVLAPYLGTQEECLFGLLTLIFLICMAATLFVTEEAVLGPPEPAEGLLVSAVSRRCCPCHVGLAFRNLGTLFPRLQQLCCRMPRTLRRLFVAELCSWMALMTFTLFYTDFVGEGLYQGVPRAEPGTEARRHYDEGIRMGSLGLFLQCAISLVFSLVMDRLVQKFGTRSVYLASVMTFPVAAAATCLSHSVVVVTASAALTGFTFSALQILPYTLASLYHREKQVFLPKYRGDAGGSSGEDSQTTSFLPGPKPGALFPNGHVGSGSSGILAPPPALCGASACDVSMRVVVGEPPEARVVTGRGICLDLAILDSAFLLSQVAPSLFMGSIVQLSHSVTAYMVSAAGLGLVAIYFATQVVFDKNDLAKYSV", "length": 553 }, "evidence": [ { "id": "A0A8V1AEA4", "url": "https://omabrowser.org/oma/group/A0A8V1AEA4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96JT2-1", "protein_name": "Solute carrier family 45 member 3", "gene_name": "SLC45A3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVQRLWVSRLLRHRKAQLLLVNLLTFGLEVCLAAGITYVPPLLLEVGVEEKFMTMVLGIGPVLGLVCVPLLGSASDHWRGRYGRRRPFIWALSLGILLSLFLIPRAGWLAGLLCPDPRPLELALLILGVGLLDFCGQVCFTPLEALLSDLFRDPDHCRQAYSVYAFMISLGGCLGYLLPAIDWDTSALAPYLGTQEECLFGLLTLIFLTCVAATLLVAEEAALGPTEPAEGLSAPSLSPHCCPCRARLAFRNLGALLPRLHQLCCRMPRTLRRLFVAELCSWMALMTFTLFYTDFVGEGLYQGVPRAEPGTEARRHYDEGVRMGSLGLFLQCAISLVFSLVMDRLVQRFGTRAVYLASVAAFPVAAGATCLSHSVAVVTASAALTGFTFSALQILPYTLASLYHREKQVFLPKYRGDTGGASSEDSLMTSFLPGPKPGAPFPNGHVGAGGSGLLPPPPALCGASACDVSVRVVVGEPTEARVVPGRGICLDLAILDSAFLLSQVAPSLFMGSIVQLSQSVTAYMVSAAGLGLVAIYFATQVVFDKSDLAKYSA", "length": 553 }, "evidence": [ { "id": "A0A8V1AEA4", "url": "https://omabrowser.org/oma/group/A0A8V1AEA4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEA4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEA4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "transmembrane transporter activity", "id": "GO:0022857", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022857", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEA4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEA4" } ], "pmid": "" }, { "name": "sucrose:proton symporter activity", "id": "GO:0008506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008506", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEA4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEA4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "positive regulation of glucose metabolic process", "id": "GO:0010907", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010907", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEA4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEA4" } ], "pmid": "" }, { "name": "positive regulation of fatty acid biosynthetic process", "id": "GO:0045723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045723", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEA4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEA4" } ], "pmid": "" }, { "name": "regulation of oligodendrocyte differentiation", "id": "GO:0048713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048713", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEA4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEA4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1ABQ9-1", "uniprot_ac": "A0A8V1ABQ9", "uniprot_id": "A0A8V1ABQ9_CHICK", "mass": { "chemical_mass": 77044.0, "monoisotopic_mass": 77044.0 }, "refseq": { "ac": "XP_004945810", "name": "ankyrin repeat and MYND domain-containing protein 1 isoform X4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004945810" }, "gene_names": [ { "name": "ANKMY1", "type": "recommended", "evidence": [ { "id": "A0A8V1ABQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABQ9" } ] }, { "name": "ANKMY1", "type": "synonym", "evidence": [ { "id": "XP_004945810", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004945810" } ] } ], "protein_names": [ { "name": "Ankyrin repeat and MYND domain containing 1", "type": "synonym", "evidence": [ { "id": "A0A8V1ABQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABQ9/entry#names_and_taxonomy" } ] }, { "name": "ankyrin repeat and MYND domain-containing protein 1 isoform X4", "type": "synonym", "evidence": [ { "id": "XP_004945810", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004945810" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052548.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004945810.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004945810", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004945810" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABQ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABQ9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ANKMY1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABQ9", "locus": { "chromosome": "17", "start_pos": 921313, "end_pos": 948520, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028026", "url": "https://www.ensembl.org/id/ENSGALG00010028026" } ] } } ], "crossref": [ { "id": "A0A8V1ABQ9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1ABQ9", "database": "AlphaFoldDB", "categories": [] }, { "id": "417300", "url": "https://www.ncbi.nlm.nih.gov/gene/417300", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002893", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002893", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003409", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003409", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR053064", "url": "https://www.ebi.ac.uk/interpro/entry/IPR053064", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A6W2", "url": "https://www.orthodb.org/?gene=A0A8V1A6W2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ABQ9", "url": "https://www.orthodb.org/?gene=A0A8V1ABQ9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15897", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15897", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15897:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15897:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01753", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01753", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02493", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02493", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12796", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12796", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004945810", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004945810", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1A6W2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6W2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A6W2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6W2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ABQ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABQ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ABQ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABQ9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MATRRAAQLVPLRGAMADGPPGAERCAEEGGRPCERYVGQFYMDHRHGKGICYCPDGSKIQGAFYLGRVEGYATREWKDGRTFQGLYKSDERFGPGVESYPDGRQDVGLWLGNHLIKLCTEVPGSFSVLDYPEHYRYVDDSSQRKYISVKEDPFLRSYKHLPFDDKDIFPEGVLAYSHNMDHLTLTHSFLEGCDAHYFENTTELPEEDPWPVANGTPLLVRMQMHAYKHRQQKRWETIQLLLRRGADPNVASVPSHLLFFAVKAADAKAVKLLLEKGARTDVRLPSKFRGLSPLHIAASIPGEEGVQITEYLLSSALDLDARAEDGNEVYGPDEPQDKEANMSGDVTLQLKNEAGPPQEYFSSYNGPVPEEGGRTALHIACEREGNSEHARDVIRLLLMHKANPNTLWSGHSPLSLAIASGNDLAVVELLKRGADPNLPLSGAVKSALCAAVSTAYEHQRTTAQRTALVDKLLEAGADILAPVTLQEGKRKAVGTAVDFAYYKYYQDRRIANTPYHMLSASEQEVFQTRQSLLEHITAKLREHVILKEKEWDQEELRRSKKLDSAIHVCASKKKERNHHEEQGRLPIFKYCYQCGRSVGVQLSPCKRCYEVFTCSEACRRKSWNERHSLECSGLLEKSTIQTVPSAGTAGCKKNIVCKNGREVEEEKRGRGKSKVKTSGRETHQKND", "length": 687, "header": "tr|A0A8V1ABQ9-1|A0A8V1ABQ9_CHICK Isoform 1 of Ankyrin repeat and MYND domain containing 1 OS=Gallus gallus OX=9031 GN=ANKMY1 PE=4 SV=1 CANONICAL=A0A8V1ABQ9-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A6W2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABQ9/entry#A0A8V1A6W2-1", "sequence": { "sequence": "MDHRHGKGICYCPDGSKIQGAFYLGRVEGYATREWKDGRTFQGLYKSDERFGPGVESYPDGRQDVGLWLGNHLIKLCTEVPGSFSVLDYPEHYRYVDDSSQRKYISVKEDPFLRSYKHLPFDDKDIFPEGVLAYSHNMDHLTLTHSFLEGCDAHYFENTTELPEEDPWPVANGTPLLVRMQMHAYKHRQQKRWETIQLLLRRGADPNVASVPSHLLFFAVKAADAKAVKLLLEKGARTDVRLPSKFRGLSPLHIAASIPGEEGVQITEYLLSSALDLDARAEDGNEVYGPDEPQDKEANMSGDVTLQLKNEAGPPQEYFSSYNGPVPEEGGRTALHIACEREGNSEHARDVIRLLLMHKANPNTLWSGHSPLSLAIASGNDLAVVELLKRGADPNLPLSGAVKSALCAAVSTAYEHQRTTAQRTALVDKLLEAGADILAPVTLQEGKRKAVGTAVDFAYYKYYQDRRIANTPYHMLSASEQEVFQTRQSLLEHITAKLREHVILKEKEWDQEELRRSKKLDSAIHVCASKKKERNHHEEQGRLPIFKYCYQCGRSVGVQLSPCKRCYEVFTCSEACRRKSWNERHSLECSGLLEKSTIQTVPSAGTAGCKKNIVCKNGREVEEEKRGRGKSKVKTSGRETHQKND", "length": 645, "header": "tr|A0A8V1A6W2-1|A0A8V1ABQ9_CHICK Computationally mapped isoform of Ankyrin repeat and MYND domain containing 1 OS=Gallus gallus OX=9031 GN=ANKMY1 PE=4 SV=1 CANONICAL=A0A8V1ABQ9-1" }, "locus": { "chromosome": "17", "start_pos": 947434, "end_pos": 921463, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067921.1", "url": "https://www.ensembl.org/id/ENSGALT00010067921.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041664.1", "url": "https://www.ensembl.org/id/ENSGALP00010041664.1" } ] } }, { "isoform_ac": "A0A8V1ABQ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABQ9/entry#A0A8V1ABQ9-1", "sequence": { "sequence": "MATRRAAQLVPLRGAMADGPPGAERCAEEGGRPCERYVGQFYMDHRHGKGICYCPDGSKIQGAFYLGRVEGYATREWKDGRTFQGLYKSDERFGPGVESYPDGRQDVGLWLGNHLIKLCTEVPGSFSVLDYPEHYRYVDDSSQRKYISVKEDPFLRSYKHLPFDDKDIFPEGVLAYSHNMDHLTLTHSFLEGCDAHYFENTTELPEEDPWPVANGTPLLVRMQMHAYKHRQQKRWETIQLLLRRGADPNVASVPSHLLFFAVKAADAKAVKLLLEKGARTDVRLPSKFRGLSPLHIAASIPGEEGVQITEYLLSSALDLDARAEDGNEVYGPDEPQDKEANMSGDVTLQLKNEAGPPQEYFSSYNGPVPEEGGRTALHIACEREGNSEHARDVIRLLLMHKANPNTLWSGHSPLSLAIASGNDLAVVELLKRGADPNLPLSGAVKSALCAAVSTAYEHQRTTAQRTALVDKLLEAGADILAPVTLQEGKRKAVGTAVDFAYYKYYQDRRIANTPYHMLSASEQEVFQTRQSLLEHITAKLREHVILKEKEWDQEELRRSKKLDSAIHVCASKKKERNHHEEQGRLPIFKYCYQCGRSVGVQLSPCKRCYEVFTCSEACRRKSWNERHSLECSGLLEKSTIQTVPSAGTAGCKKNIVCKNGREVEEEKRGRGKSKVKTSGRETHQKND", "length": 687, "header": "tr|A0A8V1ABQ9-1|A0A8V1ABQ9_CHICK Isoform 1 of Ankyrin repeat and MYND domain containing 1 OS=Gallus gallus OX=9031 GN=ANKMY1 PE=4 SV=1 CANONICAL=A0A8V1ABQ9-1" }, "locus": { "chromosome": "17", "start_pos": 948315, "end_pos": 921463, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067923.1", "url": "https://www.ensembl.org/id/ENSGALT00010067923.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041666.1", "url": "https://www.ensembl.org/id/ENSGALP00010041666.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABQ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABQ9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 200, "end_pos": 202, "annotation": "n_glycosylation_sequon" }, { "start_pos": 214, "end_pos": 216, "annotation": "n_glycosylation_sequon" }, { "start_pos": 341, "end_pos": 343, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1ABQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABQ9" }, { "id": "PS50865", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50865" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "MYND-type", "eco_id": "ECO_0000259", "start_pos": 591, "end_pos": 631, "start_aa": "Cys", "end_aa": "Cys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 200, "end_pos": 202 }, { "start_pos": 214, "end_pos": 216 }, { "start_pos": 341, "end_pos": 343 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AEN9-1", "uniprot_ac": "A0A8V1AEN9", "uniprot_id": "A0A8V1AEN9_CHICK", "mass": { "chemical_mass": 62151.0, "monoisotopic_mass": 62151.0 }, "refseq": {}, "gene_names": [ { "name": "DPP7", "type": "recommended", "evidence": [ { "id": "A0A8V1AEN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEN9" } ] } ], "protein_names": [ { "name": "Dipeptidyl peptidase 2", "type": "recommended", "evidence": [ { "id": "A0A8V1AEN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEN9/entry#names_and_taxonomy" } ] }, { "name": "3.4.14.2", "type": "synonym", "evidence": [ { "id": "A0A8V1AEN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEN9/entry#names_and_taxonomy" } ] }, { "name": "Dipeptidyl aminopeptidase II", "type": "synonym", "evidence": [ { "id": "A0A8V1AEN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEN9/entry#names_and_taxonomy" } ] }, { "name": "Dipeptidyl peptidase 7", "type": "synonym", "evidence": [ { "id": "A0A8V1AEN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEN9/entry#names_and_taxonomy" } ] }, { "name": "Dipeptidyl peptidase II", "type": "synonym", "evidence": [ { "id": "A0A8V1AEN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEN9/entry#names_and_taxonomy" } ] }, { "name": "Quiescent cell proline dipeptidase", "type": "synonym", "evidence": [ { "id": "A0A8V1AEN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEN9/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Plays an important role in the degradation of some oligopeptides.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEN9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEN9#function" }, { "database": "UniProtKB", "id": "ARBA00057675", "url": "https://www.uniprot.org/uniprotkb/ARBA00057675#function" }, { "database": "UniProtKB", "id": "A0A8V1AIZ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIZ0#function" }, { "database": "UniProtKB", "id": "A0A8V1A6Z0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6Z0#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEN9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEN9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "DPP7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEN9", "locus": { "chromosome": "17", "start_pos": 1005156, "end_pos": 984384, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028042", "url": "https://www.ensembl.org/id/ENSGALG00010028042" } ] } } ], "crossref": [ { "id": "A0A8V1AEN9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AEN9", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR008758", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008758", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029058", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029058", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042269", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042269", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A6Z0", "url": "https://www.orthodb.org/?gene=A0A8V1A6Z0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AEN9", "url": "https://www.orthodb.org/?gene=A0A8V1AEN9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AIZ0", "url": "https://www.orthodb.org/?gene=A0A8V1AIZ0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11010", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11010", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11010:SF107", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11010:SF107", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05577", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05577", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-6798695", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1A6Z0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6Z0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A6Z0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6Z0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AEN9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEN9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AEN9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEN9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AIZ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIZ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AIZ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIZ0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGGDRRRKDPGRCPGRQHGGASVGMAPARSREERGSVTCCCRSHVRSRRWSPRARSGPCVEQSGAERDAAMGTRSPQLLLFVLSLLLPVRGAPAAQPAGPGLEERLFPQVRDHFRFEAGGNETFPQRYLLSAKFWKKGFGPIFFYTGNEGNIWTFAENSDFIFELAEQQQALVIFAEHRYYGKSLPFGLESTQLKNTHLLTVEQALADYAVLITELKQQYGAAGCPVIAFGGSYGGMLSAYMRMKYPNVVDGALAASAPVLSVAGLGDPTQFFRDVTADFQKSIPGCVPAVQRAFQQIRDLFLSGAYDEISSKMATCSKISSKEDLYQLFGFARNAFTMIAMMDYPYKTDFMGHLPANPVKVGCEQILAHTDPIQGLAALVGVFYNSSGSAQCYDVYRLYRPCADPTGCGTGADAEAWDYQVCTEINLTFNSNNVTDMFPEMPFTEAMREQYCWSRWRVRPRAQWLRINFWGGDLKSASNIIFSNGDLDPWAGGGINSSLSPSLTAVTIQGGAHHLDLRGHNPADPPSVIEARKLEASIISNWVKSARMERAREQRGVAPAGALQ", "length": 565, "header": "tr|A0A8V1AEN9-1|A0A8V1AEN9_CHICK Isoform 1 of Dipeptidyl peptidase 2 OS=Gallus gallus OX=9031 GN=DPP7 PE=1 SV=1 CANONICAL=A0A8V1AEN9-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A6Z0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEN9/entry#A0A8V1A6Z0-1", "sequence": { "sequence": "MGTRSPQLLLFVLSLLLPVRGAPAKFWKKGFGPIFFYTGNEGNIWTFAENSDFIFELAEQQQALVIFAEHRYYGKSLPFGLESTQLKNTHLLTVEQALADYAVLITELKQQYGAAGCPVIAFGGSYGGMLSAYMRMKYPNVVDGALAASAPVLSVAGLGDPTQFFRDVTADFQKSIPGCVPAVQRAFQQIRDLFLSGAYDEISSKMATCSKISSKEDLYQLFGFARNAFTMIAMMDYPYKTDFMGHLPANPVKVGCEQILAHTDPIQGLAALVGVFYNSSGSAQCYDVYRLYRPCADPTGCGTGADAEAWDYQVCTEINLTFNSNNVTDMFPEMPFTEAMREQYCWSRWRVRPRAQWLRINFWGGDLKSASNIIFSNGDLDPWAGGGINSSLSPSLTAVTIQGGAHHLDLRGHNPADPPSVIEARKLEASIISNWVKSARMERAREQRGVAPAGALQ", "length": 457, "header": "tr|A0A8V1A6Z0-1|A0A8V1AEN9_CHICK Computationally mapped isoform of Dipeptidyl peptidase 2 OS=Gallus gallus OX=9031 GN=DPP7 PE=1 SV=1 CANONICAL=A0A8V1AEN9-1" }, "locus": { "chromosome": "17", "start_pos": 1004195, "end_pos": 984793, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067951.1", "url": "https://www.ensembl.org/id/ENSGALT00010067951.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041694.1", "url": "https://www.ensembl.org/id/ENSGALP00010041694.1" } ] } }, { "isoform_ac": "A0A8V1AEN9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEN9/entry#A0A8V1AEN9-1", "sequence": { "sequence": "MGGDRRRKDPGRCPGRQHGGASVGMAPARSREERGSVTCCCRSHVRSRRWSPRARSGPCVEQSGAERDAAMGTRSPQLLLFVLSLLLPVRGAPAAQPAGPGLEERLFPQVRDHFRFEAGGNETFPQRYLLSAKFWKKGFGPIFFYTGNEGNIWTFAENSDFIFELAEQQQALVIFAEHRYYGKSLPFGLESTQLKNTHLLTVEQALADYAVLITELKQQYGAAGCPVIAFGGSYGGMLSAYMRMKYPNVVDGALAASAPVLSVAGLGDPTQFFRDVTADFQKSIPGCVPAVQRAFQQIRDLFLSGAYDEISSKMATCSKISSKEDLYQLFGFARNAFTMIAMMDYPYKTDFMGHLPANPVKVGCEQILAHTDPIQGLAALVGVFYNSSGSAQCYDVYRLYRPCADPTGCGTGADAEAWDYQVCTEINLTFNSNNVTDMFPEMPFTEAMREQYCWSRWRVRPRAQWLRINFWGGDLKSASNIIFSNGDLDPWAGGGINSSLSPSLTAVTIQGGAHHLDLRGHNPADPPSVIEARKLEASIISNWVKSARMERAREQRGVAPAGALQ", "length": 565, "header": "tr|A0A8V1AEN9-1|A0A8V1AEN9_CHICK Isoform 1 of Dipeptidyl peptidase 2 OS=Gallus gallus OX=9031 GN=DPP7 PE=1 SV=1 CANONICAL=A0A8V1AEN9-1" }, "locus": { "chromosome": "17", "start_pos": 1004195, "end_pos": 984583, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067955.1", "url": "https://www.ensembl.org/id/ENSGALT00010067955.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041698.1", "url": "https://www.ensembl.org/id/ENSGALP00010041698.1" } ] } }, { "isoform_ac": "A0A8V1AIZ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEN9/entry#A0A8V1AIZ0-1", "sequence": { "sequence": "MGGDRRRKDPGRCPGRQHGGASVGMAPARSREERGSVTCCCRSHVRSRRWSPRARSGPCVEQSGAERDAAMGTRSPQLLLFVLSLLLPVRGAPAAQPAGPGLEERLFPQVRDHFRFEAGGNETFPQRYLLSAKFWKKGFGPIFFYTGNEGNIWTFAENSDFIFELAEQQQALVIFAEHRYYGKSLPFGLESTQLKNTHLLTVEQALADYAVLITELKQQYGAAGCPVIAFGGSYGGMLSAYMRMKYPNVVDGALAASAPVLSVAGLGDPTQFFRDVTADFQKSIPGCVPAVQRAFQQIRDLFLSGAYDEISSKMATCSKISSKEDLYQLFGFARNAFTMIAMMDYPYKTDFMGHLPANPVKVGCEQILAHTDPIQGLAALVGVFYNSSGSAQCYDVYRLYRPCADPTGCGTGADAEAWDYQVCTEINLTFNSNNVTDMFPEMPFTEAMREQYCWSRWRVRPRAQWLRINFWGGDLKSASNIIFSNGDLDPWAGGGINSSLSPSLTAVTIQGGAHHLDLR", "length": 519, "header": "tr|A0A8V1AIZ0-1|A0A8V1AEN9_CHICK Computationally mapped isoform of Dipeptidyl peptidase 2 OS=Gallus gallus OX=9031 GN=DPP7 PE=1 SV=1 CANONICAL=A0A8V1AEN9-1" }, "locus": { "chromosome": "17", "start_pos": 1004559, "end_pos": 984583, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067952.1", "url": "https://www.ensembl.org/id/ENSGALT00010067952.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041695.1", "url": "https://www.ensembl.org/id/ENSGALP00010041695.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-GGA-6798695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798695", "resource": "Reactome", "description": "Neutrophil degranulation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "dipeptidyl-peptidase activity", "id": "GO:0008239", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008239", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEN9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEN9" } ], "pmid": "" }, { "name": "serine-type exopeptidase activity", "id": "GO:0070008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070008", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEN9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEN9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEN9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEN9" } ], "pmid": "" }, { "name": "lysosome", "id": "GO:0005764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005764", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEN9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEN9" } ], "pmid": "" }, { "name": "cytoplasmic vesicle", "id": "GO:0031410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031410", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEN9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEN9" } ], "pmid": "" }, { "name": "vesicle", "id": "GO:0031982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031982", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEN9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEN9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEN9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEN9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 121, "end_pos": 123, "annotation": "n_glycosylation_sequon" }, { "start_pos": 386, "end_pos": 388, "annotation": "n_glycosylation_sequon" }, { "start_pos": 427, "end_pos": 429, "annotation": "n_glycosylation_sequon" }, { "start_pos": 434, "end_pos": 436, "annotation": "n_glycosylation_sequon" }, { "start_pos": 497, "end_pos": 499, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-GGA-6798751", "name": "Exocytosis of azurophil granule lumen proteins", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "extracellular region, azurophil granule lumen", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0X868-1", "A0A8V0XNR7-1", "A0A8V1AFG6-1", "A2JDL7-1", "F1NI04-1", "F1NML7-1", "F1NQI0-1", "A0A1D5PSE5-1", "P27043-1", "P30374-1", "A0A1D5PN36-1", "A0A1L1RSD2-1", "Q90629-1", "A0A8V0XXM5-1", "A0A8V0ZN26-1", "A0A8V1A4Q4-1", "A0A1D5PM49-1", "A0A8V0YHC8-1", "A0A8V0YL25-1", "A0A8V0YSD2-1", "E1BS94-1", "E1BSN7-1", "A0A8V0YVV2-1", "A0A8V0YW12-1", "A0A8V0Z0Z6-1", "A0A1D5PJC6-1", "A0A8V1AEN9-1", "F1NTQ2-1", "A0A1D5PXN4-1", "P00698-1", "A0A8V0Y6N9-1", "A0A8V0Y726-1", "A0A8V0ZQV0-1" ], "evidence": [ { "id": "R-GGA-6798751", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798751" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5PJC6", "gene_name": "CPPED1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A1D5PJC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJC6" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A1D5PJC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJC6" } ] } ] }, { "uniprot_ac": "A0A1D5PM49", "gene_name": "GALNS", "activity": [ { "ec_number": "3.1.6.4", "activity": "Hydrolysis of the 6-sulfate groups of the N-acetyl-D-galactosamine 6-sulfate units of chondroitin sulfate and of the D-galactose 6-sulfate units of keratan sulfate.", "evidence": [ { "id": "A0A1D5PM49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PM49" } ] }, { "ec_number": "3.1.6.4", "activity": "", "evidence": [ { "id": "A0A1D5PM49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PM49" } ] } ] }, { "uniprot_ac": "A0A1D5PN36", "gene_name": "LOC107054567", "activity": [ { "ec_number": "3.4.21.4", "activity": "Preferential cleavage: Arg-|-Xaa, Lys-|-Xaa.", "evidence": [ { "id": "A0A1D5PN36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PN36" } ] }, { "ec_number": "3.4.21.4", "activity": "", "evidence": [ { "id": "A0A1D5PN36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PN36" } ] } ] }, { "uniprot_ac": "A0A1D5PSE5", "gene_name": "ACLY", "activity": [ { "ec_number": "2.3.3.8", "activity": "oxaloacetate + acetyl-CoA + ADP + phosphate = citrate + ATP + CoA.", "evidence": [ { "id": "A0A1D5PSE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PSE5" } ] }, { "ec_number": "2.3.3.8", "activity": "", "evidence": [ { "id": "A0A1D5PSE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PSE5" } ] } ] }, { "uniprot_ac": "A0A1D5PXN4", "gene_name": "PRKCD", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PXN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PXN4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A1D5PXN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PXN4" } ] } ] }, { "uniprot_ac": "A0A1L1RSD2", "gene_name": "GUSB", "activity": [ { "ec_number": "3.2.1.31", "activity": "a beta-D-glucuronoside + H2O = D-glucuronate + an alcohol.", "evidence": [ { "id": "A0A1L1RSD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RSD2" } ] }, { "ec_number": "3.2.1.31", "activity": "", "evidence": [ { "id": "A0A1L1RSD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RSD2" } ] } ] }, { "uniprot_ac": "A0A8V0X868", "gene_name": "GGH", "activity": [ { "ec_number": "3.4.19.9", "activity": "(6S)-5,6,7,8-tetrahydrofolyl-(gamma-L-Glu)(n) + (n-1) H2O = (6S)-5,6,7,8-tetrahydrofolate + (n-1) L-glutamate.", "evidence": [ { "id": "A0A8V0X868", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X868" } ] }, { "ec_number": "3.4.19.9", "activity": "", "evidence": [ { "id": "A0A8V0X868", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X868" } ] } ] }, { "uniprot_ac": "A0A8V0XNR7", "gene_name": "CTSC", "activity": [ { "ec_number": "3.4.14.1", "activity": "Release of an N-terminal dipeptide, Xaa-Yaa-|-Zaa-, except when Xaa is Arg or Lys, or Yaa or Zaa is Pro.", "evidence": [ { "id": "A0A8V0XNR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNR7" } ] }, { "ec_number": "3.4.14.1", "activity": "", "evidence": [ { "id": "A0A8V0XNR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNR7" } ] } ] }, { "uniprot_ac": "A0A8V0XXM5", "gene_name": "ARSA", "activity": [ { "ec_number": "3.1.6.8", "activity": "an N-acyl-1-beta-D-(3-O-sulfo)-galactosyl-sphing-4-enine + H2O = a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine + sulfate + H(+).", "evidence": [ { "id": "A0A8V0XXM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXM5" } ] }, { "ec_number": "3.1.6.8", "activity": "", "evidence": [ { "id": "A0A8V0XXM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXM5" } ] } ] }, { "uniprot_ac": "A0A8V0Y6N9", "gene_name": "NAPRT", "activity": [ { "ec_number": "6.3.4.21", "activity": "5-phospho-alpha-D-ribose 1-diphosphate + nicotinate + ATP + H2O = nicotinate beta-D-ribonucleotide + ADP + phosphate + diphosphate.", "evidence": [ { "id": "A0A8V0Y6N9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6N9" } ] }, { "ec_number": "6.3.4.21", "activity": "", "evidence": [ { "id": "A0A8V0Y6N9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6N9" } ] } ] }, { "uniprot_ac": "A0A8V0Y726", "gene_name": "TXNDC5", "activity": [ { "ec_number": "5.3.4.1", "activity": "Catalyzes the rearrangement of -S-S- bonds in proteins.", "evidence": [ { "id": "A0A8V0Y726", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y726" } ] }, { "ec_number": "5.3.4.1", "activity": "", "evidence": [ { "id": "A0A8V0Y726", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y726" } ] } ] }, { "uniprot_ac": "A0A8V0YHC8", "gene_name": "VCP", "activity": [ { "ec_number": "3.6.4.6", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YHC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHC8" } ] }, { "ec_number": "3.6.4.6", "activity": "", "evidence": [ { "id": "A0A8V0YHC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHC8" } ] } ] }, { "uniprot_ac": "A0A8V0YL25", "gene_name": "PRDX6", "activity": [ { "ec_number": "1.11.1.27", "activity": "a hydroperoxide + 2 glutathione = an alcohol + glutathione disulfide + H2O.", "evidence": [ { "id": "A0A8V0YL25", 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"categories": [ "Enzyme and Pathway" ] }, { "id": "64116", "url": "https://www.rhea-db.org/rhea/64116", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1A6Z3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6Z3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A6Z3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6Z3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A9I7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9I7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A9I7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9I7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ACD9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACD9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ACD9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACD9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AEF4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEF4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AEF4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEF4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTLERLWQVLDPLWADPRVLSALFCGSAAAVVLLKRLGHRRIQQKMEEARRARDLALERMEKAARRFKQENPGTQTAHILSLTMVELAEKLKEGSLSPESVLYSYMGKALEVNREVNCVIDFIHGCEDQLQKVKQQKEKGLLYGIPVSIKDHIDCKGHVSSAGLVKFLGQVKEEDSVIVQVLKSQGAIPFVKTNIPQTMINYDCSNLIFGQTLNPLNHQKTPGGSSGGEGALIAGGGSLLGIGSDVAGSIRLPSSFCGLCGLKPTGFRISKLGVISPITGMNSVIGMLGPIARDVDSLALCMKALLCEEMFRLDPTVPPIPFDEEVYTSSKPLRIGYYEEDGYFQPSPSMKRAVQQTRKLLQEAGHTIVPFAPPKIDYMVDELFTRGIFSDGAAHLVDSFKGDIVDPNLKSQFNTYKLPALVKRILAIILKPIYPRIARDLSALCGVGSAKNLWDQHAAVAVYRTEFIAKWRKQKLDVILCPVLGPAFNHGYAGKLFAATSYTNLYNVLNFPAGVVPVSTVTRADEEELKHYRGHYEDPWDKRLKEDETLKSRLLTANTVPSHGAAGNDLIILRHAAEVSEIIRSVGPDLCMMEDIGMLRTEEPTNLCIALADSSCIAGGAVRSIQPIYSNGKFLTGCLILRLLANVALQLLVHFDWN", "length": 658, "header": "tr|A0A8V1ACD9-1|A0A8V1ACD9_CHICK Isoform 1 of Fatty acid amide hydrolase OS=Gallus gallus OX=9031 GN=FAAH PE=3 SV=1 CANONICAL=A0A8V1ACD9-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A6Z3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACD9/entry#A0A8V1A6Z3-1", "sequence": { "sequence": "MDKKDLLLSTAAVVLLKRLGHRRIQQKMEEARRARDLALERMEKAARRFKQENPGTQTAHILSLTMVELAEKLKEGSLSPESVLYSYMGKALEVNREVNCVIDFIHGCEDQLQKVKQQKEKGLLYGIPVSIKDHIDCKGHVSSAGLVKFLGQVKEEDSVIVQVLKSQGAIPFVKTNIPQTMINYDCSNLIFGQTLNPLNHQKTPGGSSGGEGALIAGGGSLLGIGSDVAGSIRLPSSFCGLCGLKPTGFRISKLGVISPITGMNSVIGMLGPIARDVDSLALCMKALLCEEMFRLDPTVPPIPFDEEVYTSSKPLRIGYYEEDGYFQPSPSMKRAVQQTRKLLQEAGHTIVPFAPPKIDYMVDELFTRGIFSDGAAHLVDSFKGDIVDPNLKSQFNTYKLPALVKRILAIILKPIYPRIARDLSALCGVGSAKNLWDQHAAVAVYRTEFIAKWRKQKLDVILCPVLGPAFNHGYAGKLFAATSYTNLYNVLNFPAGVVPVSTVTRADEEELKHYRGHYEDPWDKRLKEAVEGAVGLPVAVQCVALPWQEELCLRFMKEVENLSRGMRRNA", "length": 570, "header": "tr|A0A8V1A6Z3-1|A0A8V1ACD9_CHICK Computationally mapped isoform of Fatty acid amide hydrolase OS=Gallus gallus OX=9031 GN=FAAH PE=3 SV=1 CANONICAL=A0A8V1ACD9-1" }, "locus": { "chromosome": "8", "start_pos": 21316746, "end_pos": 21305937, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065624.1", "url": "https://www.ensembl.org/id/ENSGALT00010065624.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039890.1", "url": "https://www.ensembl.org/id/ENSGALP00010039890.1" } ] } }, { "isoform_ac": "A0A8V1A9I7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACD9/entry#A0A8V1A9I7-1", "sequence": { "sequence": "MRAAVPSVPAVLCGSVGLLLLLLRWRRWRGLWRKVKEARERQERGLEQMDKAVRAFRQQHPSVDMVSILSLSLPELSKKIQDGSLPPEHVFYAYVGKALQIARETNCITEYMQESETQLQHTKPGEKKGLLYGVPVSIKDSINCQGHDSILGFVKNIDKPVAEDSVLVQVLKRQGAIPFVKTNVPQSLISYDCNNLIFGQTCNPLLYTRTPGGSSGGEGALIGGGGSILGFGTDLGGSLRFPAAFCGICALKPTGNRLSKKGVVSGIFGQKSVTAAVGPMAKDVESLALCMRALLCEDMFNLDSTVPPLPFNEEVYSSTQPLRIGYYETDFFTMPSPAMRRAVRETKQLLEEAGHTLVPFELTNVDYSVYNFCFRGMFADGGVTFLKNFEGELEKGNIGILSWLMKSPNWIKTLLSWITKPFVPRLSNVIRSMRANTVEELWSLHHEIEESCHQFIAQWKKLNLDVMLCPMLGPALLIGYPAKLSVAVSYTMLYNSLDFPVGVVPVTLATDEDEKELKNYQGYFQDWWDRTLATAFSSAEGMPVAVQCVALPWQEELCLRFMKEVENLSRGMRRNA", "length": 576, "header": "tr|A0A8V1A9I7-1|A0A8V1ACD9_CHICK Computationally mapped isoform of Fatty acid amide hydrolase OS=Gallus gallus OX=9031 GN=FAAH PE=3 SV=1 CANONICAL=A0A8V1ACD9-1" }, "locus": { "chromosome": "8", "start_pos": 21327010, "end_pos": 21305937, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065626.1", "url": "https://www.ensembl.org/id/ENSGALT00010065626.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039892.1", "url": "https://www.ensembl.org/id/ENSGALP00010039892.1" } ] } }, { "isoform_ac": "A0A8V1ACD9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACD9/entry#A0A8V1ACD9-1", "sequence": { "sequence": "MTLERLWQVLDPLWADPRVLSALFCGSAAAVVLLKRLGHRRIQQKMEEARRARDLALERMEKAARRFKQENPGTQTAHILSLTMVELAEKLKEGSLSPESVLYSYMGKALEVNREVNCVIDFIHGCEDQLQKVKQQKEKGLLYGIPVSIKDHIDCKGHVSSAGLVKFLGQVKEEDSVIVQVLKSQGAIPFVKTNIPQTMINYDCSNLIFGQTLNPLNHQKTPGGSSGGEGALIAGGGSLLGIGSDVAGSIRLPSSFCGLCGLKPTGFRISKLGVISPITGMNSVIGMLGPIARDVDSLALCMKALLCEEMFRLDPTVPPIPFDEEVYTSSKPLRIGYYEEDGYFQPSPSMKRAVQQTRKLLQEAGHTIVPFAPPKIDYMVDELFTRGIFSDGAAHLVDSFKGDIVDPNLKSQFNTYKLPALVKRILAIILKPIYPRIARDLSALCGVGSAKNLWDQHAAVAVYRTEFIAKWRKQKLDVILCPVLGPAFNHGYAGKLFAATSYTNLYNVLNFPAGVVPVSTVTRADEEELKHYRGHYEDPWDKRLKEDETLKSRLLTANTVPSHGAAGNDLIILRHAAEVSEIIRSVGPDLCMMEDIGMLRTEEPTNLCIALADSSCIAGGAVRSIQPIYSNGKFLTGCLILRLLANVALQLLVHFDWN", "length": 658, "header": "tr|A0A8V1ACD9-1|A0A8V1ACD9_CHICK Isoform 1 of Fatty acid amide hydrolase OS=Gallus gallus OX=9031 GN=FAAH PE=3 SV=1 CANONICAL=A0A8V1ACD9-1" }, "locus": { "chromosome": "8", "start_pos": 21315811, "end_pos": 21304329, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065625.1", "url": "https://www.ensembl.org/id/ENSGALT00010065625.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039891.1", "url": "https://www.ensembl.org/id/ENSGALP00010039891.1" } ] } }, { "isoform_ac": "A0A8V1AEF4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACD9/entry#A0A8V1AEF4-1", "sequence": { "sequence": "MTLERLWQVLDPLWADPRVLSALFCGSAAAVVLLKRLGHRRIQQKMEEARRARDLALERMEKAARRFKQENPGTQTAHILSLTMVELAEKLKEGSLSPESVLYSYMGKALEVNREVNCVIDFIHGCEDQLQKVKQQKEKGLLYGIPVSIKDHIDCKGHVSSAGLVKFLGQVKEEDSVIVQVLKSQGAIPFVKTNIPQTMINYDCSNLIFGQTLNPLNHQKTPGGSSGGEGALIAGGGSLLGIGSDVAGSIRLPSSFCGLCGLKPTGFRISKLGVISPITGMNSVIGMLGPIARDVDSLALCMKALLCEEMFRLDPTVPPIPFDEEVYTSSKPLRIGYYEEDGYFQPSPSMKRAVQQTRKLLQEAGHTIVPFAPPKIDYMVDELFTRGIFSDGAAHLVDSFKGDIVDPNLKSQFNTYKLPALVKRILAIILKPIVYRTEFIAKWRKQKLDVILCPVLGPAFNHGYAGKLFAATSYTNLYNVLNFPAGVVPVSTVTRADEEELKHYRGHYEDPWDKRLKEAVEGAVGLPVAVQCVALPWQEELCLRFMKEVENLSRGMRRNA", "length": 560, "header": "tr|A0A8V1AEF4-1|A0A8V1AEF4_CHICK Computationally mapped isoform of Fatty-acid amide hydrolase 1 OS=Gallus gallus OX=9031 GN=FAAH PE=3 SV=1 CANONICAL=A0A8V1ACD9-1" }, "locus": { "chromosome": "8", "start_pos": 21315811, "end_pos": 21305937, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065623.1", "url": "https://www.ensembl.org/id/ENSGALT00010065623.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039889.1", "url": "https://www.ensembl.org/id/ENSGALP00010039889.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACD9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACD9" } ], "pmid": "" }, { "name": "fatty acid amide hydrolase activity", "id": "GO:0017064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017064", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACD9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACD9" } ], "pmid": "" }, { "name": "amidase activity", "id": "GO:0004040", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004040", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACD9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACD9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "lipid catabolic process", "id": "GO:0016042", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016042", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACD9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACD9" } ], "pmid": "" }, { "name": "fatty acid catabolic process", "id": "GO:0009062", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009062", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACD9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACD9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "26132", "name": "", "equation": "2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerol + H2O = glycerol + (5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1C7F4-1", "A0A8V0X804-1", "Q5ZIN0-1", "A0A3Q2U9E5-1", "F1P1V6-1", "A0A8V0ZKJ9-1", "A0A8V1ACD9-1" ], "evidence": [ { "id": "26132", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/26132" } ] }, { "id": "26136", "name": "", "equation": "N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine + H2O = ethanolamine + (5Z,8Z,11Z,14Z)-eicosatetraenoate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZKJ9-1", "A0A8V1ACD9-1" ], "evidence": [ { "id": "26136", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/26136" } ] }, { "id": "26506", "name": "", "equation": "(9Z)-octadecenamide + H2O = (9Z)-octadecenoate + NH4(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZKJ9-1", "A0A8V1ACD9-1" ], "evidence": [ { "id": "26506", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/26506" } ] }, { "id": "35563", "name": "", "equation": "N-(9Z-hexadecenoyl) ethanolamine + H2O = (9Z)-hexadecenoate + ethanolamine", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZKJ9-1", "A0A8V1ACD9-1" ], "evidence": [ { "id": "35563", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/35563" } ] }, { "id": "45060", "name": "", "equation": "N-(9Z-octadecenoyl) ethanolamine + H2O = ethanolamine + (9Z)-octadecenoate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZKJ9-1", "A0A8V1ACD9-1" ], "evidence": [ { "id": "45060", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/45060" } ] }, { "id": "51316", "name": "", "equation": "(9Z)-octadecenoate + glycine = N-(9Z-octadecenoyl)glycine + H2O", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q5ZL18-1", "A0A8V0ZKJ9-1", "A0A8V1ACD9-1" ], "evidence": [ { "id": "51316", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/51316" } ] }, { "id": "62976", "name": "", "equation": "(9Z,12Z,15Z)-octadecatrienamide + H2O = (9Z,12Z,15Z)-octadecatrienoate + NH4(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZKJ9-1", "A0A8V1ACD9-1" ], "evidence": [ { "id": "62976", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/62976" } ] }, { "id": "62992", "name": "", "equation": "tetradecamide + H2O = tetradecanoate + NH4(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZKJ9-1", "A0A8V1ACD9-1" ], "evidence": [ { "id": "62992", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/62992" } ] }, { "id": "62996", "name": "", "equation": "(8Z,11Z,14Z)-eicosatrienamide + H2O = (8Z,11Z,14Z)-eicosatrienoate + NH4(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZKJ9-1", "A0A8V1ACD9-1" ], "evidence": [ { "id": "62996", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/62996" } ] }, { "id": "63000", "name": "", "equation": "(11Z,14Z,17Z)-eicosatrienamide + H2O = (11Z,14Z,17Z)-eicosatrienoate + NH4(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZKJ9-1", "A0A8V1ACD9-1" ], "evidence": [ { "id": "63000", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/63000" } ] }, { "id": "63004", "name": "", "equation": "(11Z,14Z)-eicosadienamide + H2O = (11Z,14Z)-eicosadienoate + NH4(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZKJ9-1", "A0A8V1ACD9-1" ], "evidence": [ { "id": "63004", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/63004" } ] }, { "id": "63008", "name": "", "equation": "(6Z)-octadecenamide + H2O = (6Z)-octadecenoate + NH4(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZKJ9-1", "A0A8V1ACD9-1" ], "evidence": [ { "id": "63008", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/63008" } ] }, { "id": "63016", "name": "", "equation": "(5Z,8Z,11Z,14Z)-eicosatetraenamide + H2O = (5Z,8Z,11Z,14Z)-eicosatetraenoate + NH4(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZKJ9-1", "A0A8V1ACD9-1" ], "evidence": [ { "id": "63016", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/63016" } ] }, { "id": "63020", "name": "", "equation": "(9Z,12Z)-octadecadienamide + H2O = (9Z,12Z)-octadecadienoate + NH4(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZKJ9-1", "A0A8V1ACD9-1" ], "evidence": [ { "id": "63020", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/63020" } ] }, { "id": "63028", "name": "", "equation": "(15Z)-tetracosenamide + H2O = (15Z)-tetracosenoate + NH4(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZKJ9-1", "A0A8V1ACD9-1" ], "evidence": [ { "id": "63028", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/63028" } ] }, { "id": "63052", "name": "", "equation": "1-O-methyl-(5Z,8Z,11Z,14Z)-eicosatetraenoate + H2O = methanol + (5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZKJ9-1", "A0A8V1ACD9-1" ], "evidence": [ { "id": "63052", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/63052" } ] }, { "id": "63120", "name": "", "equation": "(11Z)-eicosenamide + H2O = (11Z)-eicosenoate + NH4(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZKJ9-1", "A0A8V1ACD9-1" ], "evidence": [ { "id": "63120", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/63120" } ] }, { "id": "63124", "name": "", "equation": "N-octadecanoyl ethanolamine + H2O = octadecanoate + ethanolamine", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZKJ9-1", "A0A8V1ACD9-1" ], "evidence": [ { "id": "63124", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/63124" } ] }, { "id": "63128", "name": "", "equation": "N-docosanoyl-ethanolamine + H2O = docosanoate + ethanolamine", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZKJ9-1", "A0A8V1ACD9-1" ], "evidence": [ { "id": "63128", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/63128" } ] }, { "id": "63140", "name": "", "equation": "N-tetracosanoyl-taurine + H2O = tetracosanoate + taurine", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZKJ9-1", "A0A8V1ACD9-1" ], "evidence": [ { "id": "63140", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/63140" } ] }, { "id": "63144", "name": "", "equation": "N-(15Z-tetracosenoyl)-ethanolamine + H2O = (15Z)-tetracosenoate + ethanolamine", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZKJ9-1", "A0A8V1ACD9-1" ], "evidence": [ { "id": "63144", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/63144" } ] }, { "id": "63148", "name": "", "equation": "N-(9Z-octadecenoyl)-taurine + H2O = taurine + (9Z)-octadecenoate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZKJ9-1", "A0A8V1ACD9-1" ], "evidence": [ { "id": "63148", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/63148" } ] }, { "id": "63156", "name": "", "equation": "N-docosanoyl-taurine + H2O = docosanoate + taurine", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZKJ9-1", "A0A8V1ACD9-1" ], "evidence": [ { "id": "63156", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/63156" } ] }, { "id": "63160", "name": "", "equation": "N-(15Z-tetracosenoyl)-taurine + H2O = (15Z)-tetracosenoate + taurine", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZKJ9-1", "A0A8V1ACD9-1" ], "evidence": [ { "id": "63160", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/63160" } ] }, { "id": "63164", "name": "", "equation": "N-tricosanoyl-taurine + H2O = tricosanoate + taurine", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZKJ9-1", "A0A8V1ACD9-1" ], "evidence": [ { "id": "63164", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/63164" } ] }, { "id": "64108", "name": "", "equation": "N-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-glycine + H2O = (5Z,8Z,11Z,14Z)-eicosatetraenoate + glycine", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q5ZL18-1", "A0A8V0ZKJ9-1", "A0A8V1ACD9-1" ], "evidence": [ { "id": "64108", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/64108" } ] }, { "id": "64116", "name": "", "equation": "N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-L-serine + H2O = (5Z,8Z,11Z,14Z)-eicosatetraenoate + L-serine", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q5ZL18-1", "A0A8V0ZKJ9-1", "A0A8V1ACD9-1" ], "evidence": [ { "id": "64116", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/64116" } ] } ], "reaction_participants": [], "reaction_enzymes": 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"id": "IPR036412", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036412", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:415895", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415895", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QWTHQPQ", "url": "https://omabrowser.org/oma/group/QWTHQPQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A6Z5", "url": "https://www.orthodb.org/?gene=A0A8V1A6Z5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ABT7", "url": "https://www.orthodb.org/?gene=A0A8V1ABT7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ABU2", "url": "https://www.orthodb.org/?gene=A0A8V1ABU2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12103", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12103", "database": "PANTHER", "categories": [ 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"UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ABU2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABU2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MWGGTSPSLSVDVMRDPAVGRVLLLFSCKGQLSWSGKQKWTGLLLALLLALLLALLWLSQAEALFWSDKPQQLTYSHSCLSAERRLLVAISTTRSQSVASWRGVFGVCFVLDLLPPGVCNLLNPAAIYANNEISLGDVEIYGFDYDYTLAQYSNLLHSMIFNTARDILIEQFKYPEGLGKYDYIPGFAIRGLHYDVQKSLLMKIDAFHYVQLGTAYRGLKPVPDEEVIELYGGTQHIPLYQMSDFYGKGPSLKQFMDIFSLPEMTLLSSVIDYFITHGIEFDQVHLYKDISDAIRDVHVKGVMYKWIEKDMEQYILHGDEIYAVLNRLVNHKKKLFLITNSPFSFVDKGMKHMVGKNWRDLFDMVIVQADKPNFFTDRRKPFRKLDDNGSLQWDKINQLEKGKIYKEGNLFDFLRLTGWRGSKVLYFGDHLYSDLADLMLRHGWRTGAIVPELETEIRIINTEQYMHSLTWQQALTGLLERMQMYQDAESKQVLLEWMKERQEIRSLTKNLFNPQFGSIFRTFHNPTYFSRRLVRFSDIYMASISCLLNYDVNFTFYPRRTPLQHEAPLWMDQLCTGCMKTPFLEEMVHIR", "length": 591, "header": "tr|A0A8V1ABT7-1|A0A8V1ABT7_CHICK Isoform 1 of 5'-nucleotidase domain containing 2 OS=Gallus gallus OX=9031 GN=NT5DC2 PE=1 SV=1 CANONICAL=A0A8V1ABT7-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A6Z5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABT7/entry#A0A8V1A6Z5-1", "sequence": { "sequence": "MQSLQDAAHRCRCVPGMQQRLFFLLGDFEAAVSSRRWVAVGRGSRGLLLVAAVRGRKHSKEPHIYKRRIVLLGLSGCVVPNTVNDLLPPGVCNLLNPAAIYANNEISLGDVEIYGFDYDYTLAQYSNLLHSMIFNTARDILIEQFKYPEGLGKYDYIPGFAIRGLHYDVQKSLLMKIDAFHYVQLGTAYRGLKPVPDEEVIELYGGTQHIPLYQMSDFYGKGPSLKQFMDIFSLPEMTLLSSVIDYFITHGIEFDQVHLYKDISDAIRDVHVKGVMYKWIEKDMEQYILHGDEIYAVLNRLVNHKKKLFLITNSPFSFVDKGMKHMVGKNWRDLFDMVIVQADKPNFFTDRRKPFRKLDDNGSLQWDKINQLEKGKIYKEGNLFDFLRLTGWRGSKVLYFGDHLYSDLADLMLRHGWRTGAIVPELETEIRIINTEQYMHSLTWQQALTGLLERMQMYQDAESKQVLLEWMKERQEIRSLTKNLFNPQFGSIFRTFHNPTYFSRRLVRFSDIYMASISCLLNYDVNFTFYPRRTPLQHEAPLWMDQLCTGCMKTPFLEEMVHIR", "length": 564, "header": "tr|A0A8V1A6Z5-1|A0A8V1ABT7_CHICK Computationally mapped isoform of 5'-nucleotidase domain containing 2 OS=Gallus gallus OX=9031 GN=NT5DC2 PE=1 SV=1 CANONICAL=A0A8V1ABT7-1" }, "locus": { "chromosome": "12", "start_pos": 765856, "end_pos": 743192, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067956.1", "url": "https://www.ensembl.org/id/ENSGALT00010067956.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041699.1", "url": "https://www.ensembl.org/id/ENSGALP00010041699.1" } ] } }, { "isoform_ac": "A0A8V1ABT7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABT7/entry#A0A8V1ABT7-1", "sequence": { "sequence": "MWGGTSPSLSVDVMRDPAVGRVLLLFSCKGQLSWSGKQKWTGLLLALLLALLLALLWLSQAEALFWSDKPQQLTYSHSCLSAERRLLVAISTTRSQSVASWRGVFGVCFVLDLLPPGVCNLLNPAAIYANNEISLGDVEIYGFDYDYTLAQYSNLLHSMIFNTARDILIEQFKYPEGLGKYDYIPGFAIRGLHYDVQKSLLMKIDAFHYVQLGTAYRGLKPVPDEEVIELYGGTQHIPLYQMSDFYGKGPSLKQFMDIFSLPEMTLLSSVIDYFITHGIEFDQVHLYKDISDAIRDVHVKGVMYKWIEKDMEQYILHGDEIYAVLNRLVNHKKKLFLITNSPFSFVDKGMKHMVGKNWRDLFDMVIVQADKPNFFTDRRKPFRKLDDNGSLQWDKINQLEKGKIYKEGNLFDFLRLTGWRGSKVLYFGDHLYSDLADLMLRHGWRTGAIVPELETEIRIINTEQYMHSLTWQQALTGLLERMQMYQDAESKQVLLEWMKERQEIRSLTKNLFNPQFGSIFRTFHNPTYFSRRLVRFSDIYMASISCLLNYDVNFTFYPRRTPLQHEAPLWMDQLCTGCMKTPFLEEMVHIR", "length": 591, "header": "tr|A0A8V1ABT7-1|A0A8V1ABT7_CHICK Isoform 1 of 5'-nucleotidase domain containing 2 OS=Gallus gallus OX=9031 GN=NT5DC2 PE=1 SV=1 CANONICAL=A0A8V1ABT7-1" }, "locus": { "chromosome": "12", "start_pos": 764878, "end_pos": 743192, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067953.1", "url": "https://www.ensembl.org/id/ENSGALT00010067953.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041696.1", "url": "https://www.ensembl.org/id/ENSGALP00010041696.1" } ] } }, { "isoform_ac": "A0A8V1ABU2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABT7/entry#A0A8V1ABU2-1", "sequence": { "sequence": "MAALGIAALRRGGGAAPRLLAVAVSCHGCRARSGSGPADGGHGQPREPLPGGRARRGAEPGPVAGGQPAPSEGADTRSYLWARYHEMKKLVYDLLPPGVCNLLNPAAIYANNEISLGDVEIYGFDYDYTLAQYSNLLHSMIFNTARDILIEQFKYPEGLGKYDYIPGFAIRGLHYDVQKSLLMKIDAFHYVQLGTAYRGLKPVPDEEVIELYGGTQHIPLYQMSDFYGKGPSLKQFMDIFSLPEMTLLSSVIDYFITHGIEFDQVHLYKDISDAIRDVHVKGVMYKWIEKDMEQYILHGDEIYAVLNRLVNHKKKLFLITNSPFSFVDKGMKHMVGKNWRDLFDMVIVQADKPNFFTDRRKPFRKLDDNGSLQWDKINQLEKGKIYKEGNLFDFLRLTGWRGSKVLYFGDHLYSDLADLMLRHGWRTGAIVPELETEIRIINTEQYMHSLTWQQALTGLLERMQMYQDAESKQVLLEWMKERQEIRSLTKNLFNPQFGSIFRTFHNPTYFSRRLVRFSDIYMASISCLLNYDVNFTFYPRRTPLQHEAPLWMDQLCTGCMKTPFLEEMVHIR", "length": 572, "header": "tr|A0A8V1ABU2-1|A0A8V1ABU2_CHICK Computationally mapped isoform of 5'-nucleotidase domain containing 2 OS=Gallus gallus OX=9031 GN=NT5DC2 PE=1 SV=1 CANONICAL=A0A8V1ABT7-1" }, "locus": { "chromosome": "12", "start_pos": 767584, "end_pos": 743192, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067958.1", "url": "https://www.ensembl.org/id/ENSGALT00010067958.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041701.1", "url": "https://www.ensembl.org/id/ENSGALP00010041701.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:415895", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415895", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A2I3BR81-1", "protein_name": "5'-nucleotidase domain containing 2", "gene_name": "Nt5dc2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAGAGLRATARRLLLCRGHSGPRAASSSPSCPGCGPPGPGAHCPSTPRSAPADGADLSAHLWARYQDMRRLVHDLLPPEVCSLLNPAAIYANNEISLSDVEVYGFDYDYTLAQYADALHPEIFNAARDILIEHYKYPEGIRKYDYDPSFAIRGLHYDIQKSLLMKIDAFHYVQLGTAYRGLKPVPDDEVIDLYGGTQHIPLYQMSGFYGKGPSIKQFMDIFSLPEMALLSCVVDYFLGHGLEFDQVHLYKDVTDAIRDVHVKGLMYQWIEQDMEKYILRGDETFAVLSRLVAHGKQLFLITNSPFSFVDKGMRHMVGPDWRQLFDVVIVQADKPNFFTDRRKPFRKLDEKGSLHWDRITRLEKGKIYRQGNLFDFLRLTEWRGPRVLYFGDHLYSDLADLMLRHGWRTGAIIPELEREIRIINTEQYMHSLTWQQALTGLLERMQTYQDAESRQVLATWMKERQELRCITKALFNAQFGSIFRTFHNPTYFSRRLVRFSDLYMASLSCLLNYRVDFTFYPRRTPLQHEAPLWMDQLCTGCMKTPFLGDMAHIR", "length": 553 }, "evidence": [ { "id": "A0A8V1ABT7", "url": "https://omabrowser.org/oma/group/A0A8V1ABT7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E1BNI8-1", "protein_name": "5'-nucleotidase domain containing 2", "gene_name": "NT5DC2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAGAGLRAAARRWVPRRDHGGPRAASSSPSCPGCGPPGPGAHCPGAPRSAPAPAPAGGAAEPSAHLWARYQDMRRLVHDLLPPEVCSLLNPAAIYANNEISLRDVEVYGFDYDYTLAQYSDTLHPEIFNAARDILVEHYKYPEGIRKYEYNPSFAIRGLHYDIQKSLLMKIDAFHYVQLGTAYRGLQPVPDEEVIELYGGTQHIPLYQMSGFYGKGPSIKQFMDIFSLPEMALLSCVVDHFLGHGLEFDQAHLYKDVTDAIRDVHVKGLMYQWIERDMEKYILRGDETFAVLSRLVAHGKQLFLITNSPFSFVDKGMRHMVGPDWRQLFDVVIVQADKPSFFTDRRKPFRKLDEKGSLHWDRITRLEKGKIYRQGNLFDFLRLTEWRGPRVLYFGDHLYSDLADLMLRHGWRTGAIIPELEREIRIINTEQYMHSLTWQQALTGLLERMQTYQDAESRQVLAAWMKERQELSLGASSAPSTTPPTSRGGWCASPTSTWPPSAACSTTAWTSPSTRAAPPCSTRRRSGWTSSAPAA", "length": 535 }, "evidence": [ { "id": "A0A8V1ABT7", "url": "https://omabrowser.org/oma/group/A0A8V1ABT7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1SIV9-1", "protein_name": "5'-nucleotidase domain containing 2", "gene_name": "NT5DC2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAGAGLRAAARRYLPRRDHGGPRAASSSPSCPGCGPPGPGVHCPGVPRSTPSPAPAGAAEPSAHLWARYQDMRRLVHDLLPPEVCSLLNPAAIYANNEISLQDVEVYGFDYDYTLAQYADTLHPEIFNAARDILIEHYKYPEGIRKYDYNPSFAIRGLHYDIQKSLLMKIDAFHYVQLGTAYRGLQPVPDEEVIDLYGGTQHIPLYQMSGFYGKGPSIKQFMDIFSLPEMALLSCVVDHFLGHGLEFDQAHLYKDVTDAIRDVHVKGLMYQWIEQDMEKYILRGEETFAVLNRLVAHGKQLFLITNSPFSFVDKGMRHMVGPDWRQLFDVVIVQADKPSFFTDRRKPFRKLDEKGSLHWDRITRLEKGKIYRQGNLFDFLRLTEWRGPRVLYFGDHLYSDLADLMLRHGWRTGAIIPELEREIRIINTEQYMHSLTWQQALTGLLERMQTYQDAESRQVLAAWMKERQELRCITKALFNAQFGSIFRTFHNPTYFSRRLVRFSDLYMASLSCLLNYRVDFTFYPRRTPLQHEAPLWMDQLCTGCMKTPFLGDMAHIR", "length": 557 }, "evidence": [ { "id": "A0A8V1ABT7", "url": "https://omabrowser.org/oma/group/A0A8V1ABT7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q6Q0N3-1", "protein_name": "5'-nucleotidase domain-containing protein 2", "gene_name": "Nt5dc2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGAGLRAAARRWLLCGGQGGPRAASSSPSCPGCGPPGPGAHCPSTPRSAPADGADLSAHLWARYQDMRRLVHDLLPPEVCSLLNPAAIYANNEISLSDVEVYGFDYDYTLAQYADALHPEIFSAARDILIEHYKYPEGIRKYDYDPSFAIRGLHYDIQKSLLMKIDAFHYVQLGTAYRGLQPVPDDEVVDLYGGTQHIPLYQMSGFYGKGPSIKQFMDIFSLPEMALLSCVVDYFLGHGLEFDQVHLYKDVTDAIRDVHVKGLMYQWIEQDMEKYILRGDETFAVLSRLVAHGKQLFLITNSPFSFVDKGMRHMVGPDWRQLFDVVIVQADKPNFFTDRRKPFRKLDEKGSLHWDRITRLEKGKIYRQGNLFDFLRLTEWRGPRVLYFGDHLYSDLADLMLRHGWRTGAIIPELEREIRIINTEQYMHSLTWQQALTGLLERMQTYQDAESRQVLATWMKERQELRCITKALFNAQFGSIFRTFHNPTYFSRRLVRFSDLYMASLSCLLNYSVDFTFYPRRTPLQHEAPLWMDQLCTGCMKTPFLGDMAHIR", "length": 553 }, "evidence": [ { "id": "A0A8V1ABT7", "url": "https://omabrowser.org/oma/group/A0A8V1ABT7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9H857-1", "protein_name": "5'-nucleotidase domain-containing protein 2", "gene_name": "NT5DC2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRVESGSAQERGILLESLSTLLEKTTASHEGRAPGNRELTDLLPPEVCSLLNPAAIYANNEISLRDVEVYGFDYDYTLAQYADALHPEIFSTARDILIEHYKYPEGIRKYDYNPSFAIRGLHYDIQKSLLMKIDAFHYVQLGTAYRGLQPVPDEEVIELYGGTQHIPLYQMSGFYGKGPSIKQFMDIFSLPEMALLSCVVDYFLGHSLEFDQAHLYKDVTDAIRDVHVKGLMYQWIEQDMEKYILRGDETFAVLSRLVAHGKQLFLITNSPFSFVDKGMRHMVGPDWRQLFDVVIVQADKPSFFTDRRKPFRKLDEKGSLQWDRITRLEKGKIYRQGNLFDFLRLTEWRGPRVLYFGDHLYSDLADLMLRHGWRTGAIIPELEREIRIINTEQYMHSLTWQQALTGLLERMQTYQDAESRQVLAAWMKERQELRCITKALFNAQFGSIFRTFHNPTYFSRRLVRFSDLYMASLSCLLNYRVDFTFYPRRTPLQHEAPLWMDQLCTGCMKTPFLGDMAHIR", "length": 520 }, "evidence": [ { "id": "A0A8V1ABT7", "url": "https://omabrowser.org/oma/group/A0A8V1ABT7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABT7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABT7" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABT7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABT7" } ], "pmid": "" }, { "name": "5'-nucleotidase activity", "id": "GO:0008253", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008253", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABT7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABT7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 388, "end_pos": 390, "annotation": "n_glycosylation_sequon" }, { "start_pos": 553, "end_pos": 555, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [ { "evidence": [ { "id": "A0A8V1A6Z5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6Z5#function" }, { "id": "A0A8V1A6Z5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6Z5" }, { "id": "PIRSR017434-2", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR017434-2" } ], "binding_site_uniprot": 117, "amino_acid": "Gly", "chebi_lig_id": "CHEBI_18420", "ligand": "Mg(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 117, "end_pos": 117, "start_aa": "Gly", "end_aa": "Gly", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1ABU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABU2#function" }, { "id": "A0A8V1ABU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABU2" }, { "id": "PIRSR017434-2", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR017434-2" } ], "binding_site_uniprot": 125, "amino_acid": "Ala", "chebi_lig_id": "CHEBI_18420", "ligand": "Mg(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 125, "end_pos": 125, "start_aa": "Ala", "end_aa": "Ala", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1A6Z5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6Z5#function" }, { "id": "A0A8V1A6Z5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6Z5" }, { "id": "PIRSR017434-2", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR017434-2" } ], "binding_site_uniprot": 402, "amino_acid": "Gly", "chebi_lig_id": "CHEBI_18420", "ligand": "Mg(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 402, "end_pos": 402, "start_aa": "Gly", "end_aa": "Gly", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1ABU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABU2#function" }, { "id": "A0A8V1ABU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABU2" }, { "id": "PIRSR017434-2", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR017434-2" } ], "binding_site_uniprot": 410, "amino_acid": "Leu", "chebi_lig_id": "CHEBI_18420", "ligand": "Mg(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 410, "end_pos": 410, "start_aa": "Leu", "end_aa": "Leu", "glycosite_overlap": "" } ], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 388, "end_pos": 390 }, { "start_pos": 553, "end_pos": 555 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AC12-1", "uniprot_ac": "A0A8V1AC12", "uniprot_id": "A0A8V1AC12_CHICK", "mass": { "chemical_mass": 110355.0, "monoisotopic_mass": 110355.0 }, "refseq": { "ac": "XP_015154489", "name": "signal peptide, CUB and EGF-like domain-containing protein 3 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015154489" }, "gene_names": [ { "name": "SCUBE3", "type": "recommended", "evidence": [ { "id": "A0A8V1AC12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC12" } ] }, { "name": "SCUBE3", "type": "synonym", "evidence": [ { "id": "XP_015154489", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015154489" } ] } ], "protein_names": [ { "name": "Signal peptide, CUB and EGF-like domain-containing protein 3", "type": "recommended", "evidence": [ { "id": "A0A8V1AC12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC12/entry#names_and_taxonomy" } ] }, { "name": "signal peptide, CUB and EGF-like domain-containing protein 3 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_015154489", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015154489" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052557.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015154489", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015154489" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AC12", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC12" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SCUBE3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC12", "locus": { "chromosome": "26", "start_pos": 4176382, "end_pos": 4216081, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010025917", "url": "https://www.ensembl.org/id/ENSGALG00010025917" } ] } } ], "crossref": [ { "id": "A0A8V1AC12", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AC12", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00041", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00041", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd00054", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00054", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "419896", "url": "https://www.ncbi.nlm.nih.gov/gene/419896", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000152", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000152", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000742", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000742", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000859", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000859", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001881", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001881", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009030", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009030", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011641", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011641", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018097", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018097", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024731", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024731", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026823", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026823", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035914", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035914", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049883", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049883", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052071", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052071", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A701", "url": "https://www.orthodb.org/?gene=A0A8V1A701", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A707", "url": "https://www.orthodb.org/?gene=A0A8V1A707", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AC12", "url": "https://www.orthodb.org/?gene=A0A8V1AC12", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24046", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24046", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24046:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24046:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00431", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00431", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07645", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07645", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07699", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07699", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12662", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12662", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12947", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12947", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14670", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14670", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-1474228", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1474228", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015154489", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015154489", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1A701", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A701", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A701-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A701-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A707", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A707", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A707-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A707-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AC12", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC12", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AC12-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC12-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGALQIAGLCMLALLLHSGITLANKASQDVDECVEGTDSCHIDAICQNTPKSYKCICKSGYTGDGKHCKDVDECEREDNAGCVHECVNIPGNYRCTCYDGFRLAHDGHNCLDLDECSEGNGGCQQTCVNMMGSYECFCREGFFLSDNQHTCIQRPEEGMNCMNKNHGCAHICRETPKGGIACECRPGFELTKNQRDCKLTCNYGNGGCQHTCDDTDQGPKCGCHVKFLLHSDGVTCIGERHFQQHVILETFSNETCAVNNGGCDSKCHDAATGVHCSCPMGFMLQPDRKTCKDIDECRLNNGGCDHICRNTVGSFECSCKKGYKLLINERNCQDIDECSFDRTCDHLCINTPGSFQCLCNKGYTLYGLTHCGDVDECSINRGGCKFGCINTPGSYQCTCPAGCKLHWNKKDCIELVKCLSGSVPPRATLTCNKTGKKDSCALTCASKARFQPESDSSYTVSCGTPVLRQGSQHRATNSSQQCLETVAAPIKQKASFKIKDAKCHLHPRAKGKQDEGGKAVAQGGAAPCSDCQVAFVNLKCDSSKKGKGRRARNSSGKEVTRITLEFEAEIKPEETTASCNLHCLRQKVEKKLKSAIKALKKSINQERFLLRFAGMEYEVARKLSVAPERQESCGPGQQRLGTKCVSCSQGTYYHGQTEQCVPCPSGTYQEKEGQLSCDLCPRSDAFGPVGATNITGCTGQCPPGQHSTDGFKPCQPCPRGSYQPEVGRALCFPCGGGLTTRHEGALSFQDCDTKVQCSPGHYYNTSVHRCIRCAVGTYQPDFRQNYCIACPGNTTTDFDGSTSVSQCKNRQCGGELGEYTGYIESPNYPGNYPANVECTWNINPPPKRKILIVVPEIFLPSEDECGDVLVMRKNSSPSSITTYETCQTYERPIAFTARSRKLWINFKTSEANSARGFQIPYVTYDEDYEQLVEDIVRDGRLYASENHQEILKDKKLIKAFFDVLAHPQNYFKYTEKHKEMLPRSFIKLLRSKVSSFLRPYK", "length": 1001, "header": "tr|A0A8V1AC12-1|A0A8V1AC12_CHICK Isoform 1 of Signal peptide, CUB and EGF-like domain-containing protein 3 OS=Gallus gallus OX=9031 GN=SCUBE3 PE=4 SV=1 CANONICAL=A0A8V1AC12-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A701-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC12/entry#A0A8V1A701-1", "sequence": { "sequence": "MGALQIAGLCMLALLLHSGITLANKASQDVDECVEGTDSCHIDAICQNTPKSYKCICKSGYTGDGKHCKDVDECEREDNAGCVHECVNIPGNYRCTCYDGFRLAHDGHNCLDLDECSEGNGGCQQTCVNMMGSYECFCREGFFLSDNQHTCIQRPEEGMNCMNKNHGCAHICRETPKGGIACECRPGFELTKNQRDCKLTCNYGNGGCQHTCDDTDQGPKCGCHVKFLLHSDGVTCIETCAVNNGGCDSKCHDAATGVHCSCPMGFMLQPDRKTCKDIDECRLNNGGCDHICRNTVGSFECSCKKGYKLLINERNCQDIDECSFDRTCDHLCINTPGSFQCLCNKGYTLYGLTHCGDVDECSINRGGCKFGCINTPGSYQCTCPAGCKLHWNKKDCIGSVPPRATLTCNKTGKKDSCALTCASKARFQPESDSSYTVSCGTPVLRQGSQHRATNSSQQCLETVAAPIKQKASFKIKDAKCHLHPRAKGKQDEGGKAVAQGGAAPCSDCQVAFVNLKCDSSKKGKGRRARNSSGKEVTRITLEFEAEIKPEETTASCNLHCLRQKVEKKLKSAIKALKKSINQERFLLRFAGMEYEVARKLSVAPERQESCGPGQQRLGTKCVSCSQGTYYHGQTEQCVPCPSGTYQEKEGQLSCDLCPRSDAFGPVGATNITGCTGQCPPGQHSTDGFKPCQPCPRGSYQPEVGRALCFPCGGGLTTRHEGALSFQDCDTKVQCSPGHYYNTSVHRCIRCAVGTYQPDFRQNYCIACPGNTTTDFDGSTSVSQCKNRQCGGELGEYTGYIESPNYPGNYPANVECTWNINPPPKRKILIVVPEIFLPSEDECGDVLVMRKNSSPSSITTYETCQTYERPIAFTARSRKLWINFKTSEANSARGFQIPYVTYDEDYEQLVEDIVRDGRLYASENHQEILKDKKLIKAFFDVLAHPQNYFKYTEKHKEMLPRSFIKLLRSKVSSFLRPYK", "length": 978, "header": "tr|A0A8V1A701-1|A0A8V1AC12_CHICK Computationally mapped isoform of Signal peptide, CUB and EGF-like domain-containing protein 3 OS=Gallus gallus OX=9031 GN=SCUBE3 PE=4 SV=1 CANONICAL=A0A8V1AC12-1" }, "locus": { "chromosome": "26", "start_pos": 4205571, "end_pos": 4178060, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063185.1", "url": "https://www.ensembl.org/id/ENSGALT00010063185.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039002.1", "url": "https://www.ensembl.org/id/ENSGALP00010039002.1" } ] } }, { "isoform_ac": "A0A8V1A707-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC12/entry#A0A8V1A707-1", "sequence": { "sequence": "MAGAGRSQSTADVDECVEGTDSCHIDAICQNTPKSYKCICKSGYTGDGKHCKDVDECEREDNAGCVHECVNIPGNYRCTCYDGFRLAHDGHNCLDLDECSEGNGGCQQTCVNMMGSYECFCREGFFLSDNQHTCIQRPEEGMNCMNKNHGCAHICRETPKGGIACECRPGFELTKNQRDCKLTCNYGNGGCQHTCDDTDQGPKCGCHVKFLLHSDGVTCIGERHFQQHVILETFSNETCAVNNGGCDSKCHDAATGVHCSCPMGFMLQPDRKTCKDIDECRLNNGGCDHICRNTVGSFECSCKKGYKLLINERNCQDIDECSFDRTCDHLCINTPGSFQCLCNKGYTLYGLTHCGDVDECSINRGGCKFGCINTPGSYQCTCPAGCKLHWNKKDCIAGACPSELVKCLSGSVPPRATLTCNKTGKKDSCALTCASKARFQPESDSSYTVSCGTPVLRQGSQHRATNSSQQCLETVAAPIKQKASFKIKDAKCHLHPRAKGKQDEGGKAVAQGGAAPCSDCQVAFVNLKCDSSKKGKGRRARNSSGKEVTRITLEFEAEIKPEETTASCNLHCLRQKVEKKLKSAIKALKKSINQERFLLRFAGMEYEVARKLSVAPERQESCGPGQQRLGTKCVSCSQGTYYHGQTEQCVPCPSGTYQEKEGQLSCDLCPRSDAFGPVGATNITGCTGQCPPGQHSTDGFKPCQPCPRGSYQPEVGRALCFPCGGGLTTRHEGALSFQDCDTKVQCSPGHYYNTSVHRCIRCAVGTYQPDFRQNYCIACPGNTTTDFDGSTSVSQCKNRQCGGELGEYTGYIESPNYPGNYPANVECTWNINPPPKRKILIVVPEIFLPSEDECGDVLVMRKNSSPSSITTYETCQTYERPIAFTARSRKLWINFKTSEANSARGFQIPYVTYDEDYEQLVEDIVRDGRLYASENHQEILKDKKLIKAFFDVLAHPQNYFKYTEKHKEMLPRSFIKLLRSKVSSFLRPYK", "length": 990, "header": "tr|A0A8V1A707-1|A0A8V1AC12_CHICK Computationally mapped isoform of Signal peptide, CUB and EGF-like domain-containing protein 3 OS=Gallus gallus OX=9031 GN=SCUBE3 PE=4 SV=1 CANONICAL=A0A8V1AC12-1" }, "locus": { "chromosome": "26", "start_pos": 4216039, "end_pos": 4178060, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063194.1", "url": "https://www.ensembl.org/id/ENSGALT00010063194.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039007.1", "url": "https://www.ensembl.org/id/ENSGALP00010039007.1" } ] } }, { "isoform_ac": "A0A8V1AC12-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC12/entry#A0A8V1AC12-1", "sequence": { "sequence": "MGALQIAGLCMLALLLHSGITLANKASQDVDECVEGTDSCHIDAICQNTPKSYKCICKSGYTGDGKHCKDVDECEREDNAGCVHECVNIPGNYRCTCYDGFRLAHDGHNCLDLDECSEGNGGCQQTCVNMMGSYECFCREGFFLSDNQHTCIQRPEEGMNCMNKNHGCAHICRETPKGGIACECRPGFELTKNQRDCKLTCNYGNGGCQHTCDDTDQGPKCGCHVKFLLHSDGVTCIGERHFQQHVILETFSNETCAVNNGGCDSKCHDAATGVHCSCPMGFMLQPDRKTCKDIDECRLNNGGCDHICRNTVGSFECSCKKGYKLLINERNCQDIDECSFDRTCDHLCINTPGSFQCLCNKGYTLYGLTHCGDVDECSINRGGCKFGCINTPGSYQCTCPAGCKLHWNKKDCIELVKCLSGSVPPRATLTCNKTGKKDSCALTCASKARFQPESDSSYTVSCGTPVLRQGSQHRATNSSQQCLETVAAPIKQKASFKIKDAKCHLHPRAKGKQDEGGKAVAQGGAAPCSDCQVAFVNLKCDSSKKGKGRRARNSSGKEVTRITLEFEAEIKPEETTASCNLHCLRQKVEKKLKSAIKALKKSINQERFLLRFAGMEYEVARKLSVAPERQESCGPGQQRLGTKCVSCSQGTYYHGQTEQCVPCPSGTYQEKEGQLSCDLCPRSDAFGPVGATNITGCTGQCPPGQHSTDGFKPCQPCPRGSYQPEVGRALCFPCGGGLTTRHEGALSFQDCDTKVQCSPGHYYNTSVHRCIRCAVGTYQPDFRQNYCIACPGNTTTDFDGSTSVSQCKNRQCGGELGEYTGYIESPNYPGNYPANVECTWNINPPPKRKILIVVPEIFLPSEDECGDVLVMRKNSSPSSITTYETCQTYERPIAFTARSRKLWINFKTSEANSARGFQIPYVTYDEDYEQLVEDIVRDGRLYASENHQEILKDKKLIKAFFDVLAHPQNYFKYTEKHKEMLPRSFIKLLRSKVSSFLRPYK", "length": 1001, "header": "tr|A0A8V1AC12-1|A0A8V1AC12_CHICK Isoform 1 of Signal peptide, CUB and EGF-like domain-containing protein 3 OS=Gallus gallus OX=9031 GN=SCUBE3 PE=4 SV=1 CANONICAL=A0A8V1AC12-1" }, "locus": { "chromosome": "26", "start_pos": 4205571, "end_pos": 4178060, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063181.1", "url": "https://www.ensembl.org/id/ENSGALT00010063181.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038999.1", "url": "https://www.ensembl.org/id/ENSGALP00010038999.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-1474228", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1474228", "resource": "Reactome", "description": "Degradation of the extracellular matrix" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "extracellular 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Isoform 1 of TBC1 domain family member 22B OS=Gallus gallus OX=9031 GN=TBC1D22B PE=4 SV=1 CANONICAL=A0A8V1ACE8-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A703-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACE8/entry#A0A8V1A703-1", "sequence": { "sequence": "MPLPSFIKDRSKANVLPMKSKKASSFHEFARNTSDAWDIGDDEDEDFTSSSSSLQTLNSKVAKATAAQVLENHSKLRVKPERVQPTLSDMPTNCKVNKSSSEAQLSRMSEEACMRTPLQKQQSLPLRPIIPLVARISDQNASGAPPMTVREKTRLEKFRQLLSSHNTDLDELRKCSWPGVPREVRPVTWRLLSGYLPANMERRKLTLQRKREEYFGFIQQYYDSRNEEHHQDTYRQIHIDIPRTNPLIPLFQQPLVQEIFERILFIWAIRHPASGYVQGINDLVTPFFVVFLSEYVEEDVENFDVTNLSQDVLRSIEADSFWCMSKLLDGIQDNYTFAQPGIQKKVKALEELVSRIDEQVHNHFRKYEVEYLQFAFRWMNNLLMRELPLRCTIRLWDTYQSEPEGFSHFHLYVCAAFLIKWRKEILDEEDFQGLLMLLQNLPTIHWGNEEIGLLLAEAYRLKYMFADAPNHYRR", "length": 474, "header": "tr|A0A8V1A703-1|A0A8V1ACE8_CHICK Computationally mapped isoform of TBC1 domain family member 22B OS=Gallus gallus OX=9031 GN=TBC1D22B PE=4 SV=1 CANONICAL=A0A8V1ACE8-1" }, "locus": { "chromosome": "26", "start_pos": 264252, "end_pos": 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"tr|A0A8V1ACE8-1|A0A8V1ACE8_CHICK Isoform 1 of TBC1 domain family member 22B OS=Gallus gallus OX=9031 GN=TBC1D22B PE=4 SV=1 CANONICAL=A0A8V1ACE8-1" }, "locus": { "chromosome": "26", "start_pos": 267742, "end_pos": 254900, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065635.1", "url": "https://www.ensembl.org/id/ENSGALT00010065635.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039901.1", "url": "https://www.ensembl.org/id/ENSGALP00010039901.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACE8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACE8" } ], "pmid": "" }, { "name": "14-3-3 protein binding", "id": "GO:0071889", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071889", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACE8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACE8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACE8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACE8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 124, "end_pos": 126, "annotation": "n_glycosylation_sequon" }, { "start_pos": 149, "end_pos": 151, "annotation": "n_glycosylation_sequon" }, { "start_pos": 192, "end_pos": 194, "annotation": "n_glycosylation_sequon" }, { "start_pos": 359, "end_pos": 361, "annotation": "n_glycosylation_sequon" }, { "start_pos": 386, "end_pos": 388, "annotation": "n_glycosylation_sequon" }, { "start_pos": 84, "end_pos": 86, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1ACE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACE8" }, { "id": "PS50086", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50086" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Rab-GAP TBC", "eco_id": "ECO_0000259", "start_pos": 231, "end_pos": 455, "start_aa": "Gly", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 124, "end_pos": 126 }, { "start_pos": 149, "end_pos": 151 }, { "start_pos": 192, "end_pos": 194 }, { "start_pos": 359, "end_pos": 361 }, { "start_pos": 386, "end_pos": 388 }, { "start_pos": 84, "end_pos": 86 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AET2-1", "uniprot_ac": "A0A8V1AET2", "uniprot_id": "A0A8V1AET2_CHICK", "mass": { "chemical_mass": 42374.0, "monoisotopic_mass": 42374.0 }, "refseq": { "ac": "NP_001185536", "name": "glycosyltransferase 8 domain-containing protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001185536" }, "gene_names": [ { "name": "GLT8D1", "type": "recommended", "evidence": [ { "id": "A0A8V1AET2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AET2" } ] }, { "name": "GLT8D1", "type": "synonym", "evidence": [ { "id": "NP_001185536", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001185536" } ] } ], "protein_names": [ { "name": "Glycosyltransferase 8 domain-containing protein 1", "type": "recommended", "evidence": [ { "id": "A0A8V1AET2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AET2/entry#names_and_taxonomy" } ] }, { "name": "glycosyltransferase 8 domain-containing protein 1", "type": "synonym", "evidence": [ { "id": "NP_001185536", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001185536" } ] }, { "name": "glycosyltransferase AD-017", "type": "synonym", "evidence": [ { "id": "NP_001185536", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001185536" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: CN210827.1, BX934022.2 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000250.1. On Sep 23, 2021 this sequence version replaced NP_001185536.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript from the same strain was available for the full length of the gene. The extent of this transcript is supported by transcript alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001185536", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001185536" } ] }, { "annotation": "In vitro, catalyzes the transfer of a galactose residue from UDP-galactose onto GalNAc and GlcNAc structures.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABX1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABX1#function" }, { "database": "UniProtKB", "id": "ARBA00094223", "url": "https://www.uniprot.org/uniprotkb/ARBA00094223#function" }, { "database": "UniProtKB", "id": "A0A8V1A724", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A724#function" }, { "database": "UniProtKB", "id": "A0A8V1AET2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AET2#function" }, { "database": "UniProtKB", "id": "A0A8V1AH85", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH85#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AET2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AET2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "GLT8D1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AET2", "locus": { "chromosome": "12", "start_pos": 835311, "end_pos": 848010, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028058", "url": "https://www.ensembl.org/id/ENSGALG00010028058" } ] } } ], "crossref": [ { "id": "A0A8V1AET2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AET2", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd06429", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06429", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "415898", "url": "https://www.ncbi.nlm.nih.gov/gene/415898", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002495", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002495", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029044", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029044", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050748", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050748", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:415898", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415898", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YKQHSNI", "url": "https://omabrowser.org/oma/group/YKQHSNI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A724", "url": "https://www.orthodb.org/?gene=A0A8V1A724", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ABX1", "url": "https://www.orthodb.org/?gene=A0A8V1ABX1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AET2", "url": "https://www.orthodb.org/?gene=A0A8V1AET2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AH85", "url": "https://www.orthodb.org/?gene=A0A8V1AH85", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13778", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13778", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13778:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13778:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01501", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01501", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001185536", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001185536", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1A724", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A724", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A724-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A724-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ABX1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABX1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ABX1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABX1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AET2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AET2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AET2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AET2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AH85", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH85", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AH85-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH85-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTLRKVNISILVAAVVIFLLVLHHNFLGLSDLLKRELTDSNPLGLQPIDFIPAAPQRLTDERNDREISVVIAASDERLGGAIAAMNSIYRNTRSNVVFYIVTLNDTVDHLRLWLRNTALKNLRYHILNFDPRVLEGKVQVDPQKADSIKPLTFARFYLPNLVPHAEKAIYVDDDIIVQDDILELYNTPLKPGHAAAFSDDCDSTTNKVAVRGAGNQYNYIGFLDYKKETIRKLAMKANTCSFNPGVFVANLTEWKLQNITKQLEKWMTLNVAEELYSRTLSGSITTPPLLIVFYKQHSSIDPLWNVRHLGSNAGKRYSPQFVKAAKLLHWNGHFKPWGRTASYAEVWEKWYVPDPTGKFSLIRRHPEAYEAK", "length": 372, "header": "tr|A0A8V1AET2-1|A0A8V1AET2_CHICK Isoform 1 of Glycosyltransferase 8 domain-containing protein 1 OS=Gallus gallus OX=9031 GN=GLT8D1 PE=1 SV=1 CANONICAL=A0A8V1AET2-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A724-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AET2/entry#A0A8V1A724-1", "sequence": { "sequence": "MTLRKVNISILVAAVVIFLLVLHHNFLGLSDLLKRELTDSNPLGLQPIDFIPAAPQRLGGAIAAMNSIYRNTRSNVVFYIVTLNDTVDHLRLWLRNTALKNLRYHILNFDPRVLEGKVQVDPQKADSIKPLTFARFYLPNLVPHAEKAIYVDDDIIVQDDILELYNTPLKPGHAAAFSDDCDSTTNKVAVRGAGNQYNYIGFLDYKKETIRKLAMKANTCSFNPGVFVANLTEWKLQNITKQLEKWMTLNVAEELYSRTLSGSITTPPLLIVFYKQHSSIDPLWNVRHLGSNAGKRYSPQFVKAAKLLHWNGHFKPWGRTASYAEVWEKWYVPDPTGKFSLIRRHPEAYEAK", "length": 352, "header": "tr|A0A8V1A724-1|A0A8V1AET2_CHICK Computationally mapped isoform of Glycosyltransferase 8 domain-containing protein 1 OS=Gallus gallus OX=9031 GN=GLT8D1 PE=1 SV=1 CANONICAL=A0A8V1AET2-1" }, "locus": { "chromosome": "12", "start_pos": 847842, "end_pos": 843369, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067988.1", "url": "https://www.ensembl.org/id/ENSGALT00010067988.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041731.1", "url": "https://www.ensembl.org/id/ENSGALP00010041731.1" } ] } }, { "isoform_ac": "A0A8V1ABX1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AET2/entry#A0A8V1ABX1-1", "sequence": { "sequence": "MTLRKVNISILVAAVVIFLLVLHHNFLGLSDLLKRELTDSNPLGLQPIDFIPAAPQRLTDERNDREISVVIAASDERLGGAIAAMNSIYRNTRSNVVFYIVTLNDTVDHLRLWLRNTALKNLRYHILNFDPRVLEGKVQVDPQKADSIKPLTFARFYLPNLVPHAEKAIYVDDDIIVQDDILELYNTPLKPGHAAAFSDDCDSTTNKVAVRGAGNQYNYIGFLDYKKETIRKLAMKANTCSFNPGVFVANLTEWKLQNITKQLEKWMTLNVAEELYSRTLSGSITTPPLLIVFYKQHSSIDPLWNVRHLGSNAGKRYSPQFVKAAKLLHWNGHFKPWGRTASYAEVWEKWYVPDPTEQPLPPGAPGDALTQVQWCSSKLHSSKGDSLCLCD", "length": 391, "header": "tr|A0A8V1ABX1-1|A0A8V1ABX1_CHICK Computationally mapped isoform of Glycosyltransferase 8 domain-containing protein 1 OS=Gallus gallus OX=9031 GN=GLT8D1 PE=1 SV=1 CANONICAL=A0A8V1AET2-1" }, "locus": { "chromosome": "12", "start_pos": 847842, "end_pos": 843180, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067990.1", "url": "https://www.ensembl.org/id/ENSGALT00010067990.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041733.1", "url": "https://www.ensembl.org/id/ENSGALP00010041733.1" } ] } }, { "isoform_ac": "A0A8V1AET2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AET2/entry#A0A8V1AET2-1", "sequence": { "sequence": "MTLRKVNISILVAAVVIFLLVLHHNFLGLSDLLKRELTDSNPLGLQPIDFIPAAPQRLTDERNDREISVVIAASDERLGGAIAAMNSIYRNTRSNVVFYIVTLNDTVDHLRLWLRNTALKNLRYHILNFDPRVLEGKVQVDPQKADSIKPLTFARFYLPNLVPHAEKAIYVDDDIIVQDDILELYNTPLKPGHAAAFSDDCDSTTNKVAVRGAGNQYNYIGFLDYKKETIRKLAMKANTCSFNPGVFVANLTEWKLQNITKQLEKWMTLNVAEELYSRTLSGSITTPPLLIVFYKQHSSIDPLWNVRHLGSNAGKRYSPQFVKAAKLLHWNGHFKPWGRTASYAEVWEKWYVPDPTGKFSLIRRHPEAYEAK", "length": 372, "header": "tr|A0A8V1AET2-1|A0A8V1AET2_CHICK Isoform 1 of Glycosyltransferase 8 domain-containing protein 1 OS=Gallus gallus OX=9031 GN=GLT8D1 PE=1 SV=1 CANONICAL=A0A8V1AET2-1" }, "locus": { "chromosome": "12", "start_pos": 847842, "end_pos": 843369, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067992.1", "url": "https://www.ensembl.org/id/ENSGALT00010067992.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041735.1", "url": "https://www.ensembl.org/id/ENSGALP00010041735.1" } ] } }, { "isoform_ac": "A0A8V1AH85-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AET2/entry#A0A8V1AH85-1", "sequence": { "sequence": "MTLRKVNISILVAAVVIFLLVLHHNFLGLSDLLKRELTDSNPLGLQPIDFIPAAPQRLTDERNDREISVVIAASDERLGGAIAAMNSIYRNTRSNVVFYIVTLNDTVDHLRLWLRNTALKNLRYHILNFDPRVLEGKVQVDPQKADSIKPLTFARFYLPNLVPHAEKAIYVDDDIIVQDDILELYNTPLKPGHAAAFSDDCDSTTNKVAVRGAGNQYNYIGFLDYKKETIRKLAMKANTCSFNPGVFVANLTEWKLQNITKQLEKWMTLNVAEELYSRTLSGSITTPPLLIVFYKQHSSIDPLWNVRHLGSNAGKRYSPQFVKAAKLLHWNGHFKPWGRTASYAEVWEKWYVPDPTGINV", "length": 360, "header": "tr|A0A8V1AH85-1|A0A8V1AET2_CHICK Computationally mapped isoform of Glycosyltransferase 8 domain-containing protein 1 OS=Gallus gallus OX=9031 GN=GLT8D1 PE=1 SV=1 CANONICAL=A0A8V1AET2-1" }, "locus": { "chromosome": "12", "start_pos": 847842, "end_pos": 841502, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067991.1", "url": "https://www.ensembl.org/id/ENSGALT00010067991.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041734.1", "url": "https://www.ensembl.org/id/ENSGALP00010041734.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:415898", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415898", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A9J7F1L5-1", "protein_name": "Glycosyltransferase 8 domain-containing protein 1", "gene_name": "Glt8d1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSFRKVSIIIWVLAIVLFLLVLHHNFLSLSSLLRNEVSDSGILGLQPIDFVADIHQHPVNGRQEEIPVVIAASEDRLGGTIAAINSIHHNTRSNVIFYIVTLNSTEDHLRSWLNSVSLKSIRYKIVNFDTKLLEGKVKEDPDQGESMKPLTFARFYLPILVPSAKKAIYMDDDVIVQGDILALYNTPLKPGHAAAFSEDCDSTSTKVIIRGAGNQYNYIGYLDYKKERIRKLSMKASTCSFNPGVFVANLTEWKRQNVTNQLEKWMKLNVEEGLYSRTLAGSITTPPLLIVFYQQHSTIDPMWNVRHLGSSAGKRYSPQFVKAAKLLHWNGHFKPWGRAASYADVWEKWYIPDPTGKFSLIRRHMDTSNIK", "length": 371 }, "evidence": [ { "id": "A0A8V1AET2", "url": "https://omabrowser.org/oma/group/A0A8V1AET2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "F1SH98-1", "protein_name": "Glycosyltransferase 8 domain-containing protein 1", "gene_name": "GLT8D1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSFRKVNIIILVVAVALFLLVLHHNFLSLNSLLRNEVSDSGIVGLQPIDFIPNAPQHAVDGRQEEIPVVIAASEDRLGGAIAAINSIQHNTRSNVIFYIVTLNGTADHLRSWLSSSTLKSIRYKIVNFDSKLLEGKVKEDPDQGESIKPLTFARFYLPILVPSAKKAIYMDDDVIVQGDILALYNTPLKPGHAAAFSEDCDSASTKVVIRGAGNQYNYIGYLDYKKERIRKLSMKASTCSFNPGVFVANLTEWKRQNITNQLEKWMKLNVEEGLYSRTLAGSITTPPLLIVFYQQHSTIDPMWNVRHLGSSAGKRYSPQFVKAAKLLHWNGHFKPWGRTASYTDIWEKWYIPDPTGKFSLIRRHVEISNIK", "length": 371 }, "evidence": [ { "id": "A0A8V1AET2", "url": "https://omabrowser.org/oma/group/A0A8V1AET2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q0V7R1-1", "protein_name": "Probable galacturonosyltransferase-like 3", "gene_name": "GATL3", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSSLRLRLCLLLLLPITISCVTVTLTDLPAFREAPAFRNGRECSKTTWIPSDHEHNPSIIHIAMTLDAIYLRGSVAGVFSVLQHASCPENIVFHFIATHRRSADLRRIISSTFPYLTYHIYHFDPNLVRSKISSSIRRALDQPLNYARIYLADLLPIAVRRVIYFDSDLVVVDDVAKLWRIDLRRHVVGAPEYCHANFTNYFTSRFWSSQGYKSALKDRKPCYFNTGVMVIDLGKWRERRVTVKLETWMRIQKRHRIYELGSLPPFLLVFAGDVEPVEHRWNQHGLGGDNLEGLCRNLHPGPVSLLHWSGKGKPWLRLDSRRPCPLDSLWAPYDLFRYSPLISDS", "length": 345 }, "evidence": [ { "id": "A0A8V1AET2", "url": "https://omabrowser.org/oma/group/A0A8V1AET2/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q5E9E7-1", "protein_name": "Glycosyltransferase 8 domain-containing protein 1", "gene_name": "GLT8D1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSFRKVNIVILVLAVALFLLVLHHNFLGLSSLLRNEVSDSGIVGLQPVDFIPNAPQRVVDGREEEIPVVIAASEDRLGGAIAAINSIQHNTRSNVIFYIVTLNGTADHLRSWLSSSNLKRIRYKIVNFDTKLLEGKVKEDPDQGESIKPLTFARFYLPILVPRAKKAIYMDDDVIVQGDILALYNTPLKPGHAAAFSEDCDSTSAKVVIRGAGNQYNYIGYLDYKKERIRELSMKASTCSFNPGVFVANLTEWRRQNITNQLEKWMKLNVEEGLYSRTLAGSITTPPLLIVFYQQHSTIDPMWNVRHLGSSAGKRYSPQFVKAAKLLHWNGHFKPWGRTASYTDVWEKWYIPDPTGKFSLIRRHVEISNTK", "length": 371 }, "evidence": [ { "id": "A0A8V1AET2", "url": "https://omabrowser.org/oma/group/A0A8V1AET2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q68CQ7-1", "protein_name": "Glycosyltransferase 8 domain-containing protein 1", "gene_name": "GLT8D1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSFRKVNIIILVLAVALFLLVLHHNFLSLSSLLRNEVTDSGIVGPQPIDFVPNALRHAVDGRQEEIPVVIAASEDRLGGAIAAINSIQHNTRSNVIFYIVTLNNTADHLRSWLNSDSLKSIRYKIVNFDPKLLEGKVKEDPDQGESMKPLTFARFYLPILVPSAKKAIYMDDDVIVQGDILALYNTALKPGHAAAFSEDCDSASTKVVIRGAGNQYNYIGYLDYKKERIRKLSMKASTCSFNPGVFVANLTEWKRQNITNQLEKWMKLNVEEGLYSRTLAGSITTPPLLIVFYQQHSTIDPMWNVRHLGSSAGKRYSPQFVKAAKLLHWNGHLKPWGRTASYTDVWEKWYIPDPTGKFNLIRRYTEISNIK", "length": 371 }, "evidence": [ { "id": "A0A8V1AET2", "url": "https://omabrowser.org/oma/group/A0A8V1AET2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6NSU3-1", "protein_name": "Glycosyltransferase 8 domain-containing protein 1", "gene_name": "Glt8d1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSFRKVNIIIWVLAVVLFLLVLHHNFLSLSSLLKNDISDSGIVGLQPIDFVASAHQHPVSERQEEIPVVIAASEDRLGGTIAAINSVHQNTRSNVMFYIVTFNSTADHLRSWLNSGSLKSIRYKIVNFDTKLLEGKVKQDPDQGESMKPLTFARFYLPILVPSAKKAIYMDDDVIVQGDILALYNTPLKPGHAAAFSEDCDSASTKVIIRGAGNQYNYIGYLDYKKERIRKLSMKASTCSFNPGVFVANLTEWKRQNVTNQLEKWMKLNVEEGLYSRTLAGSITTPPLLIVFYQQHSTIDPMWNVRHLGSSAGKRYSPQFVKAAKLLHWNGHFKPWGRTASYADVWEKWYIPDPTGKFSLIRRHMDTSNIK", "length": 371 }, "evidence": [ { "id": "A0A8V1AET2", "url": "https://omabrowser.org/oma/group/A0A8V1AET2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "UDP-glycosyltransferase activity", "id": "GO:0008194", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008194", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AET2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AET2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AET2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AET2" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AET2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AET2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 104, "end_pos": 106, "annotation": "n_glycosylation_sequon" }, { "start_pos": 250, "end_pos": 252, "annotation": "n_glycosylation_sequon" }, { "start_pos": 258, "end_pos": 260, "annotation": "n_glycosylation_sequon" }, { "start_pos": 7, "end_pos": 9, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 104, "end_pos": 106 }, { "start_pos": 250, "end_pos": 252 }, { "start_pos": 258, "end_pos": 260 }, { "start_pos": 7, "end_pos": 9 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AC56-1", "uniprot_ac": "A0A8V1AC56", "uniprot_id": "A0A8V1AC56_CHICK", "mass": { "chemical_mass": 67852.0, "monoisotopic_mass": 67852.0 }, "refseq": { "ac": "XP_015155861", "name": "keratin, type II cytoskeletal 4-like isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015155861" }, "gene_names": [ { "name": "LOC768978", "type": "recommended", "evidence": [ { "id": "A0A8V1AC56", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC56" } ] }, { "name": "LOC768978", "type": "synonym", "evidence": [ { "id": "XP_015155861", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015155861" } ] } ], "protein_names": [ { "name": "IF rod domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8V1AC56", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC56/entry#names_and_taxonomy" } ] }, { "name": "keratin, type II cytoskeletal 4-like isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015155861", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015155861" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052565.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015155861.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015155861", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015155861" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AC56", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC56" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC768978", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC56", "locus": {} } ], "crossref": [ { "id": "A0A8V1AC56", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AC56", "database": "AlphaFoldDB", "categories": [] }, { "id": "768978", "url": "https://www.ncbi.nlm.nih.gov/gene/768978", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003054", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003054", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018039", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018039", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032444", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032444", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039008", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039008", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:768978", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:768978", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GGVNCKN", "url": "https://omabrowser.org/oma/group/GGVNCKN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A742", "url": "https://www.orthodb.org/?gene=A0A8V1A742", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AC56", "url": "https://www.orthodb.org/?gene=A0A8V1AC56", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45616", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45616", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45616:SF19", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45616:SF19", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00038", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00038", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16208", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16208", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015155861", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015155861", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1A742", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A742", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A742-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A742-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AC56", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC56", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AC56-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC56-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSRQAPTVRSVLGRRGFSSASEICGRSYAAACQPARCAAGAYSSRSVCNLGGSRRISYVNGVCGNGCFGDFGFGGVVGYGNAGGRVSLCGPRGYSIVRGYPDRKGEGIQGICIDERLLKPLCVGVDPLEHEIRCQEKEQIKTLNTQFACFIDKVRFLEQQNKVLETKWGLLQQYVLPKKGKNLELYFENYICDLRKRLDCLLCEKQKLGNEECATSQLVEEFKCKYEEEINRRTTVENEFVALKKDADCIFLNKEELEVKVDLLRRQLELLKCVFEEERAQVDRQLCDTSVIVKMDNNRDLDMESIIKNVECWYQEIAQKSKEEVDAFYQTRFQELQDKRGKYCDDLQSNKCEISELTRMIQKLQCELENVKKQVSCLQTSICDVEQRGDCALKDAREKHVELQNALQKAKDELACMLRDYQELLNVKLALDIEIATYKTLLEGEESRICVGNPVSVSVVSSGYNIPDDCGMLAANAAACGYGSLGRRSGRHSSQNGGFSSRSAGIHPKRVISSVAKPCVPEVFCQAGGVNCKTGGFSSRSGGYPARTVISTASGGLNARMGACQPGGVVSFGNQGCVIRQLAGPPVMVSSSPEVVACNNGVVGNFGVVRDPCVVP", "length": 616, "header": "tr|A0A8V1AC56-1|A0A8V1AC56_CHICK Isoform 1 of IF rod domain-containing protein OS=Gallus gallus OX=9031 GN=LOC768978 PE=3 SV=1 CANONICAL=A0A8V1AC56-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A742-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC56/entry#A0A8V1A742-1", "sequence": { "sequence": "MSRQAPTVRSVLGRRGFSSASEICGRSYAAACQPARCAAGAYSSRSVCNLGGSRRISYVNGVCGNGCFGDFGFGGVVGYGNAGGRVSLCGPRGYSIVRGYPDRKGEGIQGICIDERLLKPLCVGVDPLEHEIRCQEKEQIKTLNTQFACFIDKVRFLEQQNKVLETKWGLLQQYVLPKKGKNLELYFENYICDLRKRLDCLLCEKQKLGNEECATSQLVEEFKCKYEEEINRRTTVENEFVALKKDADCIFLNKEELEVKVDLLRRQLELLKCVFEEERAQVDRQLCDTSVIVKMDNNRDLDMESIIKNVECWYQEIAQKSKEEVDAFYQTRFQELQDKRGKYCDDLQSNKCEISELTRMIQKLQCELENVKKQVSCLQTSICDVEQRGDCALKDAREKHVELQNALQKAKDELACMLRDYQELLNVKLALDIEIATYKTLLEGEESRICVGNPVSVLVSSGYNIPDDCGMLAANAAACGYGSLGRRSGRHSSQNGGFSSRSAGIHPKRVISSVAKPCVPEVFCQAGGVNCKTGGFSSRSGGYPARTVISTASGGLNARMGACQPGGVVSFGNQGCVIRQLAGPPVMVSSSPEVVACNNGVVGNFGVVRDPCVVP", "length": 615, "header": "tr|A0A8V1A742-1|A0A8V1AC56_CHICK Computationally mapped isoform of IF rod domain-containing protein OS=Gallus gallus OX=9031 GN=LOC768978 PE=3 SV=1 CANONICAL=A0A8V1AC56-1" }, "locus": { "chromosome": "34", "start_pos": 2002233, "end_pos": 1996542, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063246.1", "url": "https://www.ensembl.org/id/ENSGALT00010063246.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039048.1", "url": "https://www.ensembl.org/id/ENSGALP00010039048.1" } ] } }, { "isoform_ac": "A0A8V1AC56-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC56/entry#A0A8V1AC56-1", "sequence": { "sequence": "MSRQAPTVRSVLGRRGFSSASEICGRSYAAACQPARCAAGAYSSRSVCNLGGSRRISYVNGVCGNGCFGDFGFGGVVGYGNAGGRVSLCGPRGYSIVRGYPDRKGEGIQGICIDERLLKPLCVGVDPLEHEIRCQEKEQIKTLNTQFACFIDKVRFLEQQNKVLETKWGLLQQYVLPKKGKNLELYFENYICDLRKRLDCLLCEKQKLGNEECATSQLVEEFKCKYEEEINRRTTVENEFVALKKDADCIFLNKEELEVKVDLLRRQLELLKCVFEEERAQVDRQLCDTSVIVKMDNNRDLDMESIIKNVECWYQEIAQKSKEEVDAFYQTRFQELQDKRGKYCDDLQSNKCEISELTRMIQKLQCELENVKKQVSCLQTSICDVEQRGDCALKDAREKHVELQNALQKAKDELACMLRDYQELLNVKLALDIEIATYKTLLEGEESRICVGNPVSVSVVSSGYNIPDDCGMLAANAAACGYGSLGRRSGRHSSQNGGFSSRSAGIHPKRVISSVAKPCVPEVFCQAGGVNCKTGGFSSRSGGYPARTVISTASGGLNARMGACQPGGVVSFGNQGCVIRQLAGPPVMVSSSPEVVACNNGVVGNFGVVRDPCVVP", "length": 616, "header": "tr|A0A8V1AC56-1|A0A8V1AC56_CHICK Isoform 1 of IF rod domain-containing protein OS=Gallus gallus OX=9031 GN=LOC768978 PE=3 SV=1 CANONICAL=A0A8V1AC56-1" }, "locus": { "chromosome": "34", "start_pos": 2002233, "end_pos": 1996542, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063243.1", "url": "https://www.ensembl.org/id/ENSGALT00010063243.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039045.1", "url": "https://www.ensembl.org/id/ENSGALP00010039045.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:768978", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:768978", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "keratin filament", "id": "GO:0045095", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045095", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AC56", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC56" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "keratinization", "id": "GO:0031424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031424", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AC56", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC56" } ], "pmid": "" }, { "name": "intermediate filament organization", "id": "GO:0045109", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045109", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AC56", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC56" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "structural constituent of skin epidermis", "id": "GO:0030280", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030280", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AC56", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC56" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AC56", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC56" }, { "id": "PS51842", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51842" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "IF rod", "eco_id": "ECO_0000259", "start_pos": 136, "end_pos": 449, "start_aa": "Glu", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": 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{ "uniprot_canonical_ac": "A0A8V1AC52-1", "uniprot_ac": "A0A8V1AC52", "uniprot_id": "A0A8V1AC52_CHICK", "mass": { "chemical_mass": 37902.0, "monoisotopic_mass": 37902.0 }, "refseq": {}, "gene_names": [ { "name": "GPATCH4", "type": "recommended", "evidence": [ { "id": "A0A8V1AC52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC52" } ] } ], "protein_names": [ { "name": "G-patch domain containing 4/pseudo", "type": "synonym", "evidence": [ { "id": "A0A8V1AC52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC52/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AC52", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC52" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "GPATCH4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC52", "locus": {} } ], "crossref": [ { "id": "A0A8V1AC52", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AC52", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR000467", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000467", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050656", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050656", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A789", "url": "https://www.orthodb.org/?gene=A0A8V1A789", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AC52", "url": "https://www.orthodb.org/?gene=A0A8V1AC52", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AHD5", "url": "https://www.orthodb.org/?gene=A0A8V1AHD5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23149", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23149", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23149:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23149:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01585", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01585", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1A789", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A789", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A789-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A789-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AC52", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC52", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AC52-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC52-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHD5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHD5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHD5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHD5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQMFNHPIMKCLIRAGVRFAKIDRRPNRVLLQLWKQLKDNQKLQNHPQKPGVGAMGRGLGKREDGIARPIRPSVKCGTAGVGHNAAEQFSFHWWDHVFNEAAANIAVRDEQDGVCVEARSEQRFGVSTKKPHKVPPPGSTLYGHFVKAATLTAHGEEPTKQRGGSESSEEEEEDKLDRSSARRLTDEELMRVCGGRTAHKGARHGLTMSAKLARLEQQERAFLAAKQHGGGGQPMPTQSSPPAELQDSRKKKKKKKKKREQSVDGADAEGLQSPEESGGEEEEKAERRKKKKKKKGKEKVEEVVEVMEMEAPPEDSGGAAEAEHSPGVGRKKKKKRRREAE", "length": 341, "header": "tr|A0A8V1AC52-1|A0A8V1AC52_CHICK Isoform 1 of G-patch domain containing 4/pseudo OS=Gallus gallus OX=9031 GN=GPATCH4 PE=4 SV=1 CANONICAL=A0A8V1AC52-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A789-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC52/entry#A0A8V1A789-1", "sequence": { "sequence": "ALHPNRHRLRPHGHRAAVLCRAEGAEPRRLAELHPRVAAERRSVCGVFLRGRGLGKREDGIARPIRPSVKCGTAGVGHNAAEQFSFHWWDHVFNEAAANIAVRDEQDGVCVEARSEQRFGVSTKKPHKVPPPGSTLYGHFVKAATLTAHGEEPTKQRGGSESSEEEEEDKLDRSSARRLTDEELMRVCGGRTAHKGARHGLTMSAKLARLEQQERAFLAAKQHGGGGQPMPTQSSPPAELQDSRKKKKKKKKKREQSVDGADAEGLQSPEESGGEEEEKAERRKKKKKKKGKEKVEEVVEVMEMEAPPEDSGGAAEAEHSPGVGRKKKKKRRREAE", "length": 336, "header": "tr|A0A8V1A789-1|A0A8V1AC52_CHICK Computationally mapped isoform of G-patch domain containing 4/pseudo OS=Gallus gallus OX=9031 GN=GPATCH4 PE=4 SV=1 CANONICAL=A0A8V1AC52-1" }, "locus": { "chromosome": "25", "start_pos": 428355, "end_pos": 420758, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068060.1", "url": "https://www.ensembl.org/id/ENSGALT00010068060.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041803.1", "url": "https://www.ensembl.org/id/ENSGALP00010041803.1" } ] } }, { "isoform_ac": "A0A8V1AC52-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC52/entry#A0A8V1AC52-1", "sequence": { "sequence": "MQMFNHPIMKCLIRAGVRFAKIDRRPNRVLLQLWKQLKDNQKLQNHPQKPGVGAMGRGLGKREDGIARPIRPSVKCGTAGVGHNAAEQFSFHWWDHVFNEAAANIAVRDEQDGVCVEARSEQRFGVSTKKPHKVPPPGSTLYGHFVKAATLTAHGEEPTKQRGGSESSEEEEEDKLDRSSARRLTDEELMRVCGGRTAHKGARHGLTMSAKLARLEQQERAFLAAKQHGGGGQPMPTQSSPPAELQDSRKKKKKKKKKREQSVDGADAEGLQSPEESGGEEEEKAERRKKKKKKKGKEKVEEVVEVMEMEAPPEDSGGAAEAEHSPGVGRKKKKKRRREAE", "length": 341, "header": "tr|A0A8V1AC52-1|A0A8V1AC52_CHICK Isoform 1 of G-patch domain containing 4/pseudo OS=Gallus gallus OX=9031 GN=GPATCH4 PE=4 SV=1 CANONICAL=A0A8V1AC52-1" }, "locus": { "chromosome": "25", "start_pos": 428355, "end_pos": 418048, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068062.1", "url": "https://www.ensembl.org/id/ENSGALT00010068062.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041805.1", "url": "https://www.ensembl.org/id/ENSGALP00010041805.1" } ] } }, { "isoform_ac": "A0A8V1AHD5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC52/entry#A0A8V1AHD5-1", "sequence": { "sequence": "MSAAEPSGAGMRFAERQLRRHGWTRGRGLGKREDGIARPIRPSVKCGTAGVGHNAAEQFSFHWWDHVFNEAAANIAVRDEQDGVCVEARSEQRFGVSTKKPHKVPPPGSTLYGHFVKAATLTAHGEEPTKQRGGSESSEEEEEDKLDRSSARRLTDEELMRVCGGRTAHKGARHGLTMSAKLARLEQQERAFLAAKQHGGGGQPMPTQSSPPAELQDSRKKKKKKKKKREQSVDGADAEGLQSPEESGGEEEEKAERRKKKKKKKGKEKVEEVVEVMEMEAPPEDSGGAAEAEHSPGVGRKKKKKRRREAE", "length": 311, "header": "tr|A0A8V1AHD5-1|A0A8V1AC52_CHICK Computationally mapped isoform of G-patch domain containing 4/pseudo OS=Gallus gallus OX=9031 GN=GPATCH4 PE=4 SV=1 CANONICAL=A0A8V1AC52-1" }, "locus": { "chromosome": "25", "start_pos": 428355, "end_pos": 424665, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068058.1", "url": "https://www.ensembl.org/id/ENSGALT00010068058.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041801.1", "url": "https://www.ensembl.org/id/ENSGALP00010041801.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 237, "start_aa": "Thr", "end_pos": 237, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr237", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AC52", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC52" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "nucleic acid binding", "id": "GO:0003676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AC52", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC52" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 237 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 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"field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": 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"field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AC79-1", "uniprot_ac": "A0A8V1AC79", "uniprot_id": "A0A8V1AC79_CHICK", "mass": { "chemical_mass": 26843.0, "monoisotopic_mass": 26843.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "A0A8V1AC79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC79/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AC79", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC79" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC79", "locus": {} } ], "crossref": [ { "id": "A0A8V1AC79", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AC79", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR011990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019734", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019734", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR45153", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45153", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45153:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45153:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13181", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13181", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1A7B2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7B2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A7B2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7B2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AC79", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC79", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AC79-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC79-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEAPELFATAVPEEQLEGGWDRALQGVFGPRQCLRCVESPRGVGSLLTIVQGRMQEHWQKGQDFSSCGQWEEAVICYTKAISLDPQRGQCLLDQELYSEALEAFTHAAELQPHCRVFHQRSIVCLAALGEFPEFLQMLNRELEEDVRNPDMYVLRAFFYKRSGQLALCLQDIQQALKLEPQHRAAQVLWHRLLRQGQEAKAQAVLKALRGDLHGALYEISFAIESDPLAAEFFTLR", "length": 236, "header": "tr|A0A8V1AC79-1|A0A8V1AC79_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1AC79-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A7B2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC79/entry#A0A8V1A7B2-1", "sequence": { "sequence": "EAVICYTKAISLDPQRLYEQRAEAFLQLCDFQSAKLNLMKVLMLAPARKQHCLARLALVLDLQGQCLLDQEPALPYCRLPIALSLSCSIVCLAALGEFPEFLQMLNRELEEDVRNPDMYVLRAFFYKRSGQLALCLQDIQQALKLEPQHRAAQVLWHRLLRQGQEAKAQAVLKALRGDLHGALYEISFAIESDPLAAEFFTLR", "length": 203, "header": "tr|A0A8V1A7B2-1|A0A8V1AC79_CHICK Computationally mapped isoform of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1AC79-1" }, "locus": { "chromosome": "17", "start_pos": 5607604, "end_pos": 5606535, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068086.1", "url": "https://www.ensembl.org/id/ENSGALT00010068086.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041829.1", "url": "https://www.ensembl.org/id/ENSGALP00010041829.1" } ] } }, { "isoform_ac": "A0A8V1AC79-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC79/entry#A0A8V1AC79-1", "sequence": { "sequence": "MEAPELFATAVPEEQLEGGWDRALQGVFGPRQCLRCVESPRGVGSLLTIVQGRMQEHWQKGQDFSSCGQWEEAVICYTKAISLDPQRGQCLLDQELYSEALEAFTHAAELQPHCRVFHQRSIVCLAALGEFPEFLQMLNRELEEDVRNPDMYVLRAFFYKRSGQLALCLQDIQQALKLEPQHRAAQVLWHRLLRQGQEAKAQAVLKALRGDLHGALYEISFAIESDPLAAEFFTLR", "length": 236, "header": "tr|A0A8V1AC79-1|A0A8V1AC79_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1AC79-1" }, "locus": { "chromosome": "17", "start_pos": 5608016, "end_pos": 5606535, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068088.1", "url": "https://www.ensembl.org/id/ENSGALT00010068088.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041831.1", "url": "https://www.ensembl.org/id/ENSGALP00010041831.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ 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0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AC95-1", "uniprot_ac": "A0A8V1AC95", "uniprot_id": "A0A8V1AC95_CHICK", "mass": { "chemical_mass": 119424.0, "monoisotopic_mass": 119424.0 }, "refseq": {}, "gene_names": [ { "name": "TJP3", "type": "recommended", "evidence": [ { "id": "A0A8V1AC95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC95" } ] } ], "protein_names": [ { "name": "Tight junction protein 3", "type": "synonym", "evidence": [ { "id": "A0A8V1AC95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC95/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AC95", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC95" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TJP3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC95", "locus": { "chromosome": "28", "start_pos": 1405755, "end_pos": 1418253, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028109", "url": "https://www.ensembl.org/id/ENSGALG00010028109" } ] } } ], "crossref": [ { "id": "A0A8V1AC95", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AC95", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd06727", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06727", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd06728", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06728", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd06729", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06729", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12028", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12028", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "420070", "url": "https://www.ncbi.nlm.nih.gov/gene/420070", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001478", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001478", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008144", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008144", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008145", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008145", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036028", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036028", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036034", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036034", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A7C4", "url": "https://www.orthodb.org/?gene=A0A8V1A7C4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A7C9", "url": "https://www.orthodb.org/?gene=A0A8V1A7C9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AC95", "url": "https://www.orthodb.org/?gene=A0A8V1AC95", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AF31", "url": "https://www.orthodb.org/?gene=A0A8V1AF31", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AJB4", "url": "https://www.orthodb.org/?gene=A0A8V1AJB4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13865", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13865", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13865:SF11", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13865:SF11", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00595", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00595", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00625", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00625", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07653", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07653", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1A7C4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7C4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A7C4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7C4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A7C9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7C9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A7C9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7C9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AC95", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC95", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AC95-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC95-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AF31", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF31", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AF31-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF31-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJB4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJB4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJB4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJB4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSPTPGWPLVAGRFRRNWSPRDALARGLGPPQPHGNQTQTAGAGSRCVELISVAGIPPGSRRKDPRPIARQRLAHKGLRKAAPRSVTAATNPGAQLLPGQIQPRGTSRRQRKGLVAVKKSRSRSAPPAPGLEPRHCSAPALAFPHLHWQVAAMEEMLIWEQHTVTLSKDPHRGFGFAVSGGRDRPNKVTGDTAVIVSDVVSRGPAFGQLQRRDQIVMVNGLSMENVSSSFAIQTLKTCGKIANITLKRQKKIHLPVSKSSPASPAATRRYDSDEDYDPHGVDPALRSASQHRSRDDLDHNQGYDGDSSSERSSGYHRDDRRHHKASRSRRRSQDSSHWRQSPDSGSEHRGYSRHRSTNGFGHAGDTNGLALVSGFKRLPRRDVPMKPITSVLVKKKEDEEYGLKLGSQLFIKHIVESGLAARRSSLQEGDLILKINGVASEDMSLADTQRLIEQTEGILTLLVLRDHRQFLINIPNMEDYQSDSSRMEDISDIDSDLSHPPSPKTSPRLPAAARMNSPGERRRSSRNAATDTNMDDALSRDMLEAVEQDGRHSPRSRPSARAAPKDGYSPDSRVVQFVKARSVGLQLAGGNDVGIFVSSVQEGSPADSQGIEEGDQILQVNDTSFQNLTREEAVQHLMKLPPGEDVTLRIQSKPDIYRKMISSNVGDSFYIRTHFDYEKDTPSGLSFVRGDVFHVLDTMYRGRLGSWLAVRMGRDLQEQEKGIIPNQSRAEQFASLESVLKATPGTNPSGARAEFWKLRGLRGAKKTLRKSREDLSALTKQGHYPPYERVVLKEASFKRPVVILGPITDIAMQKLSTEQPELFEIAPSVPRDGASSKVIKLDTVRQIAEKDKHALLDITPSAVERLNYVQYYPMVVFCEPESRQGIKAMRQWLAPDSRKSSRRLYAQASKMKKYCSHLFTATISLSGSGNAWYEEIKDIIRTQQSQPIWTAAEHVDVALEDSLDLLNPPSRAASGYLTCDSHANSDYDDTDGEGGAYTDGEAEDAYSHPALSRSSEPAQTYPSDGVSEQVTEQQPQGQWAQEHIRNYEHEAVRKRFTRARDDSDEDEGYEWGPATDV", "length": 1077, "header": "tr|A0A8V1AC95-1|A0A8V1AC95_CHICK Isoform 1 of Tight junction protein 3 OS=Gallus gallus OX=9031 GN=TJP3 PE=1 SV=1 CANONICAL=A0A8V1AC95-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A7C4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC95/entry#A0A8V1A7C4-1", "sequence": { "sequence": "MAVRFQVAAMEEMLIWEQHTVTLSKDPHRGFGFAVSGGRDRPNKVTGDTAVIVSDVVSRGPAFGQLQRRDQIVMVNGLSMENVSSSFAIQTLKTCGKIANITLKRQKKIHLPVSKSSPASPAATRRYDSDEDYDPHGVDPALRSASQHRSRDDLDHNQGYDGDSSSERSSGYHRDDRRHHKASRSRRRSQDSSHWRQSPDSGSEHRGYSRHRSTNGFGHAGDTNGLALVSGFKRLPRRDVPMKPITSVLVKKKEDEEYGLKLGSQLFIKHIVESGLAARRSSLQEGDLILKINGVASEDMSLADTQRLIEQTEGILTLLVLRDHRQFLINIPNMEDYQSDSSRMEDISDIDSDLSHPPSPKTSPRLPAAARMNSPGERRRSSRNAATDTNMDDALSRDMLEAVEQDGRHSPRSRPSARAAPKDGYSPDSRVVQFVKARSVGLQLAGGNDVGIFVSSVQEGSPADSQGIEEGDQILQVNDTSFQNLTREEAVQHLMKLPPGEDVTLRIQSKPDIYRKMISSNVGDSFYIRTHFDYEKDTPSGLSFVRGDVFHVLDTMYRGRLGSWLAVRMGRDLQEQEKGIIPNQSRAEQFASLESVLKATPGTNPSGARAEFWKLRGLRGAKKTLRKSREDLSALTKQGHYPPYERVVLKEASFKRPVVILGPITDIAMQKLSTEQPELFEIAPSVPRDGASSKVIKLDTVRQIAEKDKHALLDITPSAVERLNYVQYYPMVVFCEPESRQGIKAMRQWLAPDSRKSSRRLYAQASKMKKYCSHLFTATISLSGSGNAWYEEIKDIIRTQQSQPIWTAAEHVDVALEDSLDLLNPPSRAASGYLTCDSHANSDYDDTDGEGGAYTDGEAEDAYSHPALSRSSEPAQTYPSDGVSEQVTEQQPQGQWAQEHIRNYEHEAVRKRFTRARDDSDEDEGYEWGPATDV", "length": 934, "header": "tr|A0A8V1A7C4-1|A0A8V1AC95_CHICK Computationally mapped isoform of Tight junction protein 3 OS=Gallus gallus OX=9031 GN=TJP3 PE=1 SV=1 CANONICAL=A0A8V1AC95-1" }, "locus": { "chromosome": "28", "start_pos": 1413463, "end_pos": 1405989, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068101.1", "url": "https://www.ensembl.org/id/ENSGALT00010068101.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041844.1", "url": "https://www.ensembl.org/id/ENSGALP00010041844.1" } ] } }, { "isoform_ac": "A0A8V1A7C9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC95/entry#A0A8V1A7C9-1", "sequence": { "sequence": "MATHRQRLAHKGLRKAAPRSVTAATNPGAQLLPGQIQPRGTSRSAPKAGQRKGLVAVKKSRSRSAPPAPGLEPRHCSAPALAFPHLHWQVAAMEEMLIWEQHTVTLSKDPHRGFGFAVSGGRDRPNKVTGDTAVIVSDVVSRGPAFGQLQRRDQIVMVNGLSMENVSSSFAIQTLKTCGKIANITLKRQKKIHLPVSKSSPASPAATRRYDSDEDYDPHGVDPALRSASQHRSRDDLDHNQGYDGDSSSERSSGYHRDDRRHHKASRSRRRSQDSSHWRQSPDSGSEHRGYSRHRSTNGFGHAGDTNGLALVSGFKRLPRRDVPMKPITSVLVKKKEDEEYGLKLGSQLFIKHIVESGLAARRSSLQEGDLILKINGVASEDMSLADTQRLIEQTEGILTLLVLRDHRQFLINIPNMEDYQSDSSRMEDISDIDSDLSHPPSPKTSPRLPAAARMNSPGERRRSSRNAATDTNMDDALSRDMLEAVEQDGRHSPRSRPSARAAPKDGYSPDSRVVQFVKARSVGLQLAGGNDVGIFVSSVQEGSPADSQGIEEGDQILQVNDTSFQNLTREEAVQHLMKLPPGEDVTLRIQSKPDIYRKMISSNVGDSFYIRTHFDYEKDTPSGLSFVRGDVFHVLDTMYRGRLGSWLAVRMGRDLQEQEKGIIPNQSRAEQFASLESVLKATPGTNPSGARAEFWKLRGLRGAKKTLRKSREDLSALTKQGHYPPYERVVLKEASFKRPVVILGPITDIAMQKLSTEQPELFEIAPSVPRDGASSKVIKLDTVRQIAEKDKHALLDITPSAVERLNYVQYYPMVVFCEPESRQGIKAMRQWLAPDSRKSSRRLYAQASKMKKYCSHLFTATISLSGSGNAWYEEIKDIIRTQQSQPIWTAAEHVDVALEDSLDLLNPPSRAASGYLTCDSHANSDYDDTDGEGGAYTDGEAEDAYSHPALSRSSEPAQTYPSDGVSEQVTEQQPQGQWAQEHIRNYEHEAVRKRFTRARDDSDEDEGYEWGPATDV", "length": 1017, "header": "tr|A0A8V1A7C9-1|A0A8V1AC95_CHICK Computationally mapped isoform of Tight junction protein 3 OS=Gallus gallus OX=9031 GN=TJP3 PE=1 SV=1 CANONICAL=A0A8V1AC95-1" }, "locus": { "chromosome": "28", "start_pos": 1418054, "end_pos": 1405989, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068106.1", "url": "https://www.ensembl.org/id/ENSGALT00010068106.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041849.1", "url": "https://www.ensembl.org/id/ENSGALP00010041849.1" } ] } }, { "isoform_ac": "A0A8V1AC95-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC95/entry#A0A8V1AC95-1", "sequence": { "sequence": "MSPTPGWPLVAGRFRRNWSPRDALARGLGPPQPHGNQTQTAGAGSRCVELISVAGIPPGSRRKDPRPIARQRLAHKGLRKAAPRSVTAATNPGAQLLPGQIQPRGTSRRQRKGLVAVKKSRSRSAPPAPGLEPRHCSAPALAFPHLHWQVAAMEEMLIWEQHTVTLSKDPHRGFGFAVSGGRDRPNKVTGDTAVIVSDVVSRGPAFGQLQRRDQIVMVNGLSMENVSSSFAIQTLKTCGKIANITLKRQKKIHLPVSKSSPASPAATRRYDSDEDYDPHGVDPALRSASQHRSRDDLDHNQGYDGDSSSERSSGYHRDDRRHHKASRSRRRSQDSSHWRQSPDSGSEHRGYSRHRSTNGFGHAGDTNGLALVSGFKRLPRRDVPMKPITSVLVKKKEDEEYGLKLGSQLFIKHIVESGLAARRSSLQEGDLILKINGVASEDMSLADTQRLIEQTEGILTLLVLRDHRQFLINIPNMEDYQSDSSRMEDISDIDSDLSHPPSPKTSPRLPAAARMNSPGERRRSSRNAATDTNMDDALSRDMLEAVEQDGRHSPRSRPSARAAPKDGYSPDSRVVQFVKARSVGLQLAGGNDVGIFVSSVQEGSPADSQGIEEGDQILQVNDTSFQNLTREEAVQHLMKLPPGEDVTLRIQSKPDIYRKMISSNVGDSFYIRTHFDYEKDTPSGLSFVRGDVFHVLDTMYRGRLGSWLAVRMGRDLQEQEKGIIPNQSRAEQFASLESVLKATPGTNPSGARAEFWKLRGLRGAKKTLRKSREDLSALTKQGHYPPYERVVLKEASFKRPVVILGPITDIAMQKLSTEQPELFEIAPSVPRDGASSKVIKLDTVRQIAEKDKHALLDITPSAVERLNYVQYYPMVVFCEPESRQGIKAMRQWLAPDSRKSSRRLYAQASKMKKYCSHLFTATISLSGSGNAWYEEIKDIIRTQQSQPIWTAAEHVDVALEDSLDLLNPPSRAASGYLTCDSHANSDYDDTDGEGGAYTDGEAEDAYSHPALSRSSEPAQTYPSDGVSEQVTEQQPQGQWAQEHIRNYEHEAVRKRFTRARDDSDEDEGYEWGPATDV", "length": 1077, "header": "tr|A0A8V1AC95-1|A0A8V1AC95_CHICK Isoform 1 of Tight junction protein 3 OS=Gallus gallus OX=9031 GN=TJP3 PE=1 SV=1 CANONICAL=A0A8V1AC95-1" }, "locus": { "chromosome": "28", "start_pos": 1416300, "end_pos": 1405989, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068103.1", "url": "https://www.ensembl.org/id/ENSGALT00010068103.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041846.1", "url": "https://www.ensembl.org/id/ENSGALP00010041846.1" } ] } }, { "isoform_ac": "A0A8V1AF31-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC95/entry#A0A8V1AF31-1", "sequence": { "sequence": "MGQRLAHKGLRKAAPRSVTAATNPGAQLLPGQIQPRGTSRSAPKAGQRKGLVAVKKSRSRSAPPAPGLEPRHCSAPALAFPHLHWQVAAMEEMLIWEQHTVTLSKDPHRGFGFAVSGGRDRPNKVTGDTAVIVSDVVSRGPAFGQLQRRDQIVMVNGLSMENVSSSFAIQTLKTCGKIANITLKRQKKIHLPVSKSSPASPAATRRYDSDEDYDPHGVDPALRSASQHRSRDDLDHNQGYDGDSSSERSSGYHRDDRRHHKASRSRRRSQDSSHWRQSPDSGSEHRGYSRHRSTNGFGHAGDTNGLALVSGFKRLPRRDVPMKPITSVLVKKKEDEEYGLKLGSQLFIKHIVESGLAARRSSLQEGDLILKINGVASEDMSLADTQRLIEQTEGILTLLVLRDHRQFLINIPNMEDYQSDSSRMEDISDIDSDLSHPPSPKTSPRLPAAARMNSPGERRRSSRNAATDTNMDDALSRDMLEAVEQDGRHSPRSRPSARAAPKDGYSPDSRVVQFVKARSVGLQLAGGNDVGIFVSSVQEGSPADSQGIEEGDQILQVNDTSFQNLTREEAVQHLMKLPPGEDVTLRIQSKPDIYRKMISSNVGDSFYIRTHFDYEKDTPSGLSFVRGDVFHVLDTMYRGRLGSWLAVRMGRDLQEQEKGIIPNQSRAEQFASLESVLKATPGTNPSGARAEFWKLRGLRGAKKTLRKSREDLSALTKQGHYPPYERVVLKEASFKRPVVILGPITDIAMQKLSTEQPELFEIAPSVPRDGASSKVIKLDTVRQIAEKDKHALLDITPSAVERLNYVQYYPMVVFCEPESRQGIKAMRQWLAPDSRKSSRRLYAQASKMKKYCSHLFTATISLSGSGNAWYEEIKDIIRTQQSQPIWTAAEHVDVALEDSLDLLNPPSRAASGYLTCDSHANSDYDDTDGEGGAYTDGEAEDAYSHPALSRSSEPAQTYPSDGVSEQVTEQQPQGQWAQEHIRNYEHEAVRKRFTRARDDSDEDEGYEWGPATDV", "length": 1014, "header": "tr|A0A8V1AF31-1|A0A8V1AF31_CHICK Computationally mapped isoform of Tight junction protein 3 OS=Gallus gallus OX=9031 GN=TJP3 PE=1 SV=1 CANONICAL=A0A8V1AC95-1" }, "locus": { "chromosome": "28", "start_pos": 1416963, "end_pos": 1405989, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068105.1", "url": "https://www.ensembl.org/id/ENSGALT00010068105.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041848.1", "url": "https://www.ensembl.org/id/ENSGALP00010041848.1" } ] } }, { "isoform_ac": "A0A8V1AJB4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC95/entry#A0A8V1AJB4-1", "sequence": { "sequence": "MAVRFQPKAGQRKGLVAVKKSRSRSAPPAPGLEPRHCSAPALAFPHLHWQVAAMEEMLIWEQHTVTLSKDPHRGFGFAVSGGRDRPNKVTGDTAVIVSDVVSRGPAFGQLQRRDQIVMVNGLSMENVSSSFAIQTLKTCGKIANITLKRQKKIHLPVSKSSPASPAATRRYDSDEDYDPHGVDPALRSASQHRSRDDLDHNQGYDGDSSSERSSGYHRDDRRHHKASRSRRRSQDSSHWRQSPDSGSEHRGYSRHRSTNGFGHAGDTNGLALVSGFKRLPRRDVPMKPITSVLVKKKEDEEYGLKLGSQLFIKHIVESGLAARRSSLQEGDLILKINGVASEDMSLADTQRLIEQTEGILTLLVLRDHRQFLINIPNMEDYQSDSSRMEDISDIDSDLSHPPSPKTSPRLPAAARMNSPGERRRSSRNAATDTNMDDALSRDMLEAVEQDGRHSPRSRPSARAAPKDGYSPDSRVVQFVKARSVGLQLAGGNDVGIFVSSVQEGSPADSQGIEEGDQILQVNDTSFQNLTREEAVQHLMKLPPGEDVTLRIQSKPDIYRKMISSNVGDSFYIRTHFDYEKDTPSGLSFVRGDVFHVLDTMYRGRLGSWLAVRMGRDLQEQEKGIIPNQSRAEQFASLESVLKATPGTNPSGARAEFWKLRGLRGAKKTLRKSREDLSALTKQGHYPPYERVVLKEASFKRPVVILGPITDIAMQKLSTEQPELFEIAPSVPRDGASSKVIKLDTVRQIAEKDKHALLDITPSAVERLNYVQYYPMVVFCEPESRQGIKAMRQWLAPDSRKSSRRLYAQASKMKKYCSHLFTATISLSGSGNAWYEEIKDIIRTQQSQPIWTAAEHVDVALEDSLDLLNPPSRAASGYLTCDSHANSDYDDTDGEGGAYTDGEAEDAYSHPALSRSSEPAQTYPSDGVSEQVTEQQPQGQWAQEHIRNYEHEAVRKRFTRARDDSDEDEGYEWGPATDV", "length": 978, "header": "tr|A0A8V1AJB4-1|A0A8V1AC95_CHICK Computationally mapped isoform of Tight junction protein 3 OS=Gallus gallus OX=9031 GN=TJP3 PE=1 SV=1 CANONICAL=A0A8V1AC95-1" }, "locus": { "chromosome": "28", "start_pos": 1413463, "end_pos": 1405989, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068102.1", "url": "https://www.ensembl.org/id/ENSGALT00010068102.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041845.1", "url": "https://www.ensembl.org/id/ENSGALP00010041845.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 4, "start_aa": "Thr", "end_pos": 4, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr4", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AC95", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC95" } ], "pmid": "" }, { "name": "bicellular tight junction", "id": "GO:0005923", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005923", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AC95", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC95" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AC95", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC95" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "protein localization to cell-cell junction", "id": "GO:0150105", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0150105", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AC95", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC95" } ], "pmid": "" }, { "name": "cell-cell adhesion", "id": "GO:0098609", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098609", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AC95", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC95" } ], "pmid": "" }, { "name": "establishment of endothelial intestinal barrier", "id": "GO:0090557", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090557", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AC95", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC95" } ], "pmid": "" }, { "name": "cell-cell junction organization", "id": "GO:0045216", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045216", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AC95", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC95" } ], "pmid": "" }, { "name": "positive regulation of blood-brain barrier permeability", "id": "GO:1905605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905605", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AC95", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC95" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "cell adhesion molecule binding", "id": "GO:0050839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050839", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AC95", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC95" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 17, "end_pos": 19, "annotation": "n_glycosylation_sequon" }, { "start_pos": 225, "end_pos": 227, "annotation": "n_glycosylation_sequon" }, { "start_pos": 243, "end_pos": 245, "annotation": "n_glycosylation_sequon" }, { "start_pos": 36, "end_pos": 38, "annotation": "n_glycosylation_sequon" }, { "start_pos": 621, "end_pos": 623, "annotation": "n_glycosylation_sequon" }, { "start_pos": 627, "end_pos": 629, "annotation": "n_glycosylation_sequon" }, { "start_pos": 726, "end_pos": 728, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AC95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC95" }, { "id": "PS50052", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50052" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Guanylate kinase-like", "eco_id": "ECO_0000259", "start_pos": 841, "end_pos": 941, "start_aa": "Leu", "end_aa": "Arg", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1AC95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC95" }, { "id": "PS50106", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50106" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PDZ", "eco_id": "ECO_0000259", "start_pos": 163, "end_pos": 250, "start_aa": "Thr", "end_aa": "Lys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1AC95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC95" }, { "id": "PS50002", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50002" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SH3", "eco_id": "ECO_0000259", "start_pos": 666, "end_pos": 734, "start_aa": "Gly", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 4 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 17, "end_pos": 19 }, { "start_pos": 225, "end_pos": 227 }, { "start_pos": 243, "end_pos": 245 }, { "start_pos": 36, "end_pos": 38 }, { "start_pos": 621, "end_pos": 623 }, { "start_pos": 627, "end_pos": 629 }, { "start_pos": 726, "end_pos": 728 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1ACE4-1", "uniprot_ac": "A0A8V1ACE4", "uniprot_id": "A0A8V1ACE4_CHICK", "mass": { "chemical_mass": 136643.0, "monoisotopic_mass": 136643.0 }, "refseq": {}, "gene_names": [ { "name": "SUGP2", "type": "recommended", "evidence": [ { "id": "A0A8V1ACE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACE4" } ] } ], "protein_names": [ { "name": "SURP and G-patch domain containing 2", "type": "synonym", "evidence": [ { "id": "A0A8V1ACE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACE4/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACE4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACE4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SUGP2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACE4", "locus": { "chromosome": "28", "start_pos": 4122475, "end_pos": 4106435, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028124", "url": "https://www.ensembl.org/id/ENSGALG00010028124" } ] } } ], "crossref": [ { "id": "A0A8V1ACE4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1ACE4", "database": "AlphaFoldDB", "categories": [] }, { "id": "420113", "url": "https://www.ncbi.nlm.nih.gov/gene/420113", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000061", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000061", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000467", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000467", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035967", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035967", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040169", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040169", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A7G5", "url": "https://www.orthodb.org/?gene=A0A8V1A7G5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ACE4", "url": "https://www.orthodb.org/?gene=A0A8V1ACE4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AHK6", "url": "https://www.orthodb.org/?gene=A0A8V1AHK6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AJE8", "url": "https://www.orthodb.org/?gene=A0A8V1AJE8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23340", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23340", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23340:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23340:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01585", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01585", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01805", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01805", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF27652", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27652", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1A7G5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7G5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A7G5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7G5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ACE4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACE4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ACE4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACE4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHK6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHK6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHK6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHK6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJE8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJE8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJE8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJE8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLPLRSRIGSSTLRRRTEGEIRAAPQWAQEPAGRSPAPRPLPRCPPPARTFTVSSAPSLSRAAFALRLRRARVRKEGGSEGSAACRGGCWDIPGRWGGCGSAAGRRLGKMASRRITRETFDAVVQDKVKRYRAERGDALQEAMHHFKAHSRPVPRPRYEDSFHDDGRYDDAQHHSHDDWAENPRDDYPGPSYRSASPLIRKANYYHEQFGHPASRDREFGHPASHDREYGHPAVRDREYGHPASRDREYGRPASHGRDYGHPLPRGGLASHDQDYGHPDSWEATGPHETDFSSSDILGDFRSPGLMEDEYGNMENQEYDVDFGIQSDSEFRPPIRRGNIGRGRVLRGKRITRGAAKAKLFKGDIKPPLKKWNPKKLQPGPDQKPTVQPDQMPETADGPNQRPVAIQHLNQKLPPQPNQRPAIATPRPILRLPKPAHVFRNLNFDLVDKSDIFSTFGIQIIKWAGFHTIKNDAEFSRLFGALFELETETCAKMLASFKCSLKPEHRDYCFFTIKSLQHAALKTPKVDNEFLNMLLDKGAVKTKNCFFEVIKPFDKYIMRLQDRLLKGVTPLLMACNAYELSIKTNGFGNPREMASAFEITVSLCRKSLALLGQTFALASVFRQEKILEAVGLQEMAPAPTLFPNFDDSTLFGREYIENLKAWLEKSGYPIQMKKAEAESTEQLKKPSPDTKVKIPQRADRKIVETIEQLVNSIVSGTLSAKERNAQKNCPEYWFLSDEDSLEYKYYRLKLSEVQRQTSSGKEAGGEGGTLEESATESVRAMLYARKVASIKRRLFKRKRTGVIAQRGIRGRKVRRTTIGTQTLLSAGTVLKHQDKHLQDSVQSEPSVSETTTSEKNSSLDTSSSQCGTSSEVPLPSEERVDSEDLLTPPELFSSLPCQFPDVDAKTMETAEKLAKFVAQVGPEIEQFSIDNSADNPDLWFLQDRNSSAFKFYRMKVYELCPSINFSDVKEAADAGEDAKPEERNVDISEEEEEEDEEEEEDNEEETEFEEDISRPLEEMEQAEEGEDDDISAGRSVENLAEEMISKTGEEISTGETQLATSSDGAIPNLSTQASAPAPGTLFPRKRISSKSLKVGMIPASKRICLIEEPKVHEPVRIAYDRPRGCPVTKKKKKPKDLEFSHKKLTNRNVGFQMLQKMGWQEGHGLGTRGKGIREPVKVGATSAGEGLGVAGEENKEDAFDVFRQRMIQMYRQKRASK", "length": 1216, "header": "tr|A0A8V1ACE4-1|A0A8V1ACE4_CHICK Isoform 1 of SURP and G-patch domain containing 2 OS=Gallus gallus OX=9031 GN=SUGP2 PE=4 SV=1 CANONICAL=A0A8V1ACE4-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A7G5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACE4/entry#A0A8V1A7G5-1", "sequence": { "sequence": "MASRRITRETFDAVVQDKVKRYRAERGDALQEAMHHFKAHSRPVPRPRYEDSFHDDGRYDDAQHHSHDDWAENPRDDYPGPSYRSASPLIRKANYYHEQFGHPASRDREFGHPASHDREYGHPAVRDREYGHPASRDREYGRPASHGRDYGHPLPRGGLASHDQDYGHPDSWEATGPHETDFSSSDILGDFRSPGLMEDEYGNMENQEYDVDFGIQSDSEFRPPIRRGNIGRGRVLRGKRITRGAAKAKLFKGDIKPPLKKWNPKKLQPGPDQKPTVQPDQMPETADGPNQRPVAIQHLNQKLPPQPNQRPAIATPRPILRLPKPAHVFRNLNFDLVDKSDIFSTFGIQIIKWAGFHTIKNDAEFSRLFGALFELETETCAKMLASFKCSLKPEHRDYCFFTIKSLQHAALKTPKVDNEFLNMLLDKGAVKTKNCFFEVIKPFDKYIMRLQDRLLKGVTPLLMACNAYELSIKTNGFGNPREMASAFEITVSLCRKSLALLGQTFALASVFRQEKILEAVGLQEMAPAPTLFPNFDDSTLFGREYIENLKAWLEKSGYPIQMKKAEAESTEQLKKPSPDTKVKIPQRADRKIVETIEQLVNSIVSGTLSAKERNAQKNCPEYWFLSDEDSLEYKYYRLKLSEVQRQTSSGKEAGGEGGTLEESATESVRAMLYARKVASIKRRLFKRKRTGVIAQRGIRGRKVRRTTIGTQTLLSAGTVLKHQDKHLQDSVQSEPSVSETTTSEKNSSLDTSSSQCGTSSEVPLPSEERVDSEDLLTPPELFSSLPCQFPDVDAKTMETAEKLAKFVAQVGPEIEQFSIDNSADNPDLWFLQDRNSSAFKFYRMKVYELCPSINFSDVKEAADAGEDAKPEERNVDISEEEEEEDEEEEEDNEEETEFEEDISRPLEEMEQAEEGEDDDISAGRSVENLAEEMISKTGEEISTGETQLATSSDGAIPNLSTQASAPAPGTLFPRKRISSKSLKVGMIPASKRICLIEEPKVHEPVRIAYDRPRGCPVTKKKKKPKDLEFSHKKLTNRNVGFQMLQKMGWQEGHGLGTRGKGIREPVKVLRQQNYFHCKYVVHSVAC", "length": 1086, "header": "tr|A0A8V1A7G5-1|A0A8V1ACE4_CHICK Computationally mapped isoform of SURP and G-patch domain containing 2 OS=Gallus gallus OX=9031 GN=SUGP2 PE=4 SV=1 CANONICAL=A0A8V1ACE4-1" }, "locus": { "chromosome": "28", "start_pos": 4115523, "end_pos": 4107739, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068146.1", "url": "https://www.ensembl.org/id/ENSGALT00010068146.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041889.1", "url": "https://www.ensembl.org/id/ENSGALP00010041889.1" } ] } }, { "isoform_ac": "A0A8V1ACE4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACE4/entry#A0A8V1ACE4-1", "sequence": { "sequence": "MLPLRSRIGSSTLRRRTEGEIRAAPQWAQEPAGRSPAPRPLPRCPPPARTFTVSSAPSLSRAAFALRLRRARVRKEGGSEGSAACRGGCWDIPGRWGGCGSAAGRRLGKMASRRITRETFDAVVQDKVKRYRAERGDALQEAMHHFKAHSRPVPRPRYEDSFHDDGRYDDAQHHSHDDWAENPRDDYPGPSYRSASPLIRKANYYHEQFGHPASRDREFGHPASHDREYGHPAVRDREYGHPASRDREYGRPASHGRDYGHPLPRGGLASHDQDYGHPDSWEATGPHETDFSSSDILGDFRSPGLMEDEYGNMENQEYDVDFGIQSDSEFRPPIRRGNIGRGRVLRGKRITRGAAKAKLFKGDIKPPLKKWNPKKLQPGPDQKPTVQPDQMPETADGPNQRPVAIQHLNQKLPPQPNQRPAIATPRPILRLPKPAHVFRNLNFDLVDKSDIFSTFGIQIIKWAGFHTIKNDAEFSRLFGALFELETETCAKMLASFKCSLKPEHRDYCFFTIKSLQHAALKTPKVDNEFLNMLLDKGAVKTKNCFFEVIKPFDKYIMRLQDRLLKGVTPLLMACNAYELSIKTNGFGNPREMASAFEITVSLCRKSLALLGQTFALASVFRQEKILEAVGLQEMAPAPTLFPNFDDSTLFGREYIENLKAWLEKSGYPIQMKKAEAESTEQLKKPSPDTKVKIPQRADRKIVETIEQLVNSIVSGTLSAKERNAQKNCPEYWFLSDEDSLEYKYYRLKLSEVQRQTSSGKEAGGEGGTLEESATESVRAMLYARKVASIKRRLFKRKRTGVIAQRGIRGRKVRRTTIGTQTLLSAGTVLKHQDKHLQDSVQSEPSVSETTTSEKNSSLDTSSSQCGTSSEVPLPSEERVDSEDLLTPPELFSSLPCQFPDVDAKTMETAEKLAKFVAQVGPEIEQFSIDNSADNPDLWFLQDRNSSAFKFYRMKVYELCPSINFSDVKEAADAGEDAKPEERNVDISEEEEEEDEEEEEDNEEETEFEEDISRPLEEMEQAEEGEDDDISAGRSVENLAEEMISKTGEEISTGETQLATSSDGAIPNLSTQASAPAPGTLFPRKRISSKSLKVGMIPASKRICLIEEPKVHEPVRIAYDRPRGCPVTKKKKKPKDLEFSHKKLTNRNVGFQMLQKMGWQEGHGLGTRGKGIREPVKVGATSAGEGLGVAGEENKEDAFDVFRQRMIQMYRQKRASK", "length": 1216, "header": "tr|A0A8V1ACE4-1|A0A8V1ACE4_CHICK Isoform 1 of SURP and G-patch domain containing 2 OS=Gallus gallus OX=9031 GN=SUGP2 PE=4 SV=1 CANONICAL=A0A8V1ACE4-1" }, "locus": { "chromosome": "28", "start_pos": 4118042, "end_pos": 4107210, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068148.1", "url": "https://www.ensembl.org/id/ENSGALT00010068148.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041891.1", "url": "https://www.ensembl.org/id/ENSGALP00010041891.1" } ] } }, { "isoform_ac": "A0A8V1AHK6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACE4/entry#A0A8V1AHK6-1", "sequence": { "sequence": "MASRRITRETFDAVVQDKVKRYRAERGDALQEAMHHFKAHSRPVPRPRYEDSFHDDGRYDDAQHHSHDDWAENPRDDYPGPSYRSASPLIRKANYYHEQFGHPASRDREFGHPASHDREYGHPAVRDREYGHPASRDREYGRPASHGRDYGHPLPRGGLASHDQDYGHPDSWEATGPHETDFSSSDILGDFRSPGLMEDEYGNMENQEYDVDFGIQSDSEFRPPIRRGNIGRGRVLRGKRITRGAAKAKLFKGDIKPPLKKWNPKKLQPGPDQKPTVQPDQMPETADGPNQRPVAIQHLNQKLPPQPNQRPAIATPRPILRLPKPAHVFRNLNFDLVDKSDIFSTFGIQIIKWAGFHTIKNDAEFSRLFGALFELETETCAKMLASFKCSLKPEHRDYCFFTIKSLQHAALKTPKVDNEFLNMLLDKGAVKTKNCFFEVIKPFDKYIMRLQDRLLKGVTPLLMACNAYELSIKTNGFGNPREMASAFEITVSLCRKSLALLGQTFALASVFRQEKILEAVGLQEMAPAPTLFPNFDDSTLFGREYIENLKAWLEKSGYPIQMKKAEAESTEQLKKPSPDTKVKIPQRADRKIVETIEQLVNSIVSGTLSAKERNAQKNCPEYWFLSDEDSLEYKYYRLKLSEVQRQTSSGKEAGGEGGTLEESATESVRAMLYARKVASIKRRLFKRKRTGVIAQRGIRGRKVRRTTIGTQTLLSAGTVLKHQDKHLQDSVQSEPSVSETTTSEKNSSLDTSSSQCGTSSEVPLPSEERVDSEDLLTPPELFSSLPCQFPDVDAKTMETAEKLAKFVAQVGPEIEQFSIDNSADNPDLWFLQDRNSSAFKFYRMKVYELCPSINFSDVKEAADAGEDAKPEERNVDISEEEEEEDEEEEEDNEEETEFEEDISRPLEEMEQAEEGEDDDISAGRSVENLAEEMISKTGEEISTGETQLATSSDGAIPNLSTQASAPAPGTLFPRKRISSKSLKVGMIPASKRICLIEEPKVHEPVRIAYDRPRGCPVTKKKKKPKDLEFSHKKLTNRNVGFQMLQKMGWQEGHGLGTRGKGIREPVKFQALFHEDCKLQ", "length": 1079, "header": "tr|A0A8V1AHK6-1|A0A8V1ACE4_CHICK Computationally mapped isoform of SURP and G-patch domain containing 2 OS=Gallus gallus OX=9031 GN=SUGP2 PE=4 SV=1 CANONICAL=A0A8V1ACE4-1" }, "locus": { "chromosome": "28", "start_pos": 4121086, "end_pos": 4107739, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068149.1", "url": "https://www.ensembl.org/id/ENSGALT00010068149.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041892.1", "url": "https://www.ensembl.org/id/ENSGALP00010041892.1" } ] } }, { "isoform_ac": "A0A8V1AJE8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACE4/entry#A0A8V1AJE8-1", "sequence": { "sequence": "MFSCTASSNVSCAMCLEPIAARGSRRRSAALRKGRSELRRGGKMASRRITRETFDAVVQDKVKRYRAERGDALQEAMHHFKAHSRPVPRPRYEDSFHDDGRYDDAQHHSHDDWAENPRDDYPGPSYRSASPLIRKANYYHEQFGHPASRDREFGHPASHDREYGHPAVRDREYGHPASRDREYGRPASHGRDYGHPLPRGGLASHDQDYGHPDSWEATGPHETDFSSSDILGDFRSPGLMEDEYGNMENQEYDVDFGIQSDSEFRPPIRRGNIGRGRVLRGKRITRGAAKAKLFKGDIKPPLKKWNPKKLQPGPDQKPTVQPDQMPETADGPNQRPVAIQHLNQKLPPQPNQRPAIATPRPILRLPKPAHVFRNLNFDLVDKSDIFSTFGIQIIKWAGFHTIKNDAEFSRLFGALFELETETCAKMLASFKCSLKPEHRDYCFFTIKSLQHAALKTPKVDNEFLNMLLDKGAVKTKNCFFEVIKPFDKYIMRLQDRLLKGVTPLLMACNAYELSIKTNGFGNPREMASAFEITVSLCRKSLALLGQTFALASVFRQEKILEAVGLQEMAPAPTLFPNFDDSTLFGREYIENLKAWLEKSGYPIQMKKAEAESTEQLKKPSPDTKVKIPQRADRKIVETIEQLVNSIVSGTLSAKERNAQKNCPEYWFLSDEDSLEYKYYRLKLSEVQRQTSSGKEAGGEGGTLEESATESVRAMLYARKVASIKRRLFKRKRTGVIAQRGIRGRKVRRTTIGTQTLLSAGTVLKHQDKHLQDSVQSEPSVSETTTSEKNSSLDTSSSQCGTSSEVPLPSEERVDSEDLLTPPELFSSLPCQFPDVDAKTMETAEKLAKFVAQVGPEIEQFSIDNSADNPDLWFLQDRNSSAFKFYRMKVYELCPSINFSDVKEAADAGEDAKPEERNVDISEEEEEEDEEEEEDNEEETEFEEDISRPLEEMEQAEEGEDDDISAGRSVENLAEEMISKTGEEISTGETQLATSSDGAIPNLSTQASAPAPGTLFPRKRISSKSLKVGMIPASKRICLIEEPKVHEPVRIAYDRPRGCPVTKKKKKPKDLEFSHKKLTNRNVGFQMLQKMGWQEGHGLGTRGKGIREPVKVYVMGTSYSNLAAMEQAGILVVTISILTLLDVANSVFCFLLDVVFGLSKVERGDFTRFSGQAEHSLVWKLAVPCCAL", "length": 1187, "header": "tr|A0A8V1AJE8-1|A0A8V1ACE4_CHICK Computationally mapped isoform of SURP and G-patch domain containing 2 OS=Gallus gallus OX=9031 GN=SUGP2 PE=4 SV=1 CANONICAL=A0A8V1ACE4-1" }, "locus": { "chromosome": "28", "start_pos": 4115262, "end_pos": 4106634, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068147.1", "url": "https://www.ensembl.org/id/ENSGALT00010068147.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041890.1", "url": "https://www.ensembl.org/id/ENSGALP00010041890.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACE4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACE4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACE4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACE4" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACE4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACE4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACE4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACE4" } ], "pmid": "" }, { "name": "RNA splicing", "id": "GO:0008380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008380", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACE4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACE4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1067, "end_pos": 1069, "annotation": "n_glycosylation_sequon" }, { "start_pos": 855, "end_pos": 857, "annotation": "n_glycosylation_sequon" }, { "start_pos": 944, "end_pos": 946, "annotation": "n_glycosylation_sequon" }, { "start_pos": 963, "end_pos": 965, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1ACE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACE4" }, { "id": "PS50174", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50174" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-patch", "eco_id": "ECO_0000259", "start_pos": 1145, "end_pos": 1191, "start_aa": "Asn", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1ACE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACE4" }, { "id": "PS50128", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50128" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SURP motif", "eco_id": "ECO_0000259", "start_pos": 908, "end_pos": 951, "start_aa": "Thr", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1067, "end_pos": 1069 }, { "start_pos": 855, "end_pos": 857 }, { "start_pos": 944, "end_pos": 946 }, { "start_pos": 963, "end_pos": 965 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1ACZ9-1", "uniprot_ac": "A0A8V1ACZ9", "uniprot_id": "A0A8V1ACZ9_CHICK", "mass": { "chemical_mass": 57120.0, "monoisotopic_mass": 57120.0 }, "refseq": {}, "gene_names": [ { "name": "C4BPG", "type": "recommended", "evidence": [ { "id": "A0A8V1ACZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACZ9" } ] } ], "protein_names": [ { "name": "Complement component 4 binding protein, GPI-anchored", "type": "synonym", "evidence": [ { "id": "A0A8V1ACZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACZ9/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "This protein recognizes C4b and C3b fragments that condense with cell-surface hydroxyl or amino groups when nascent C4b and C3b are locally generated during C4 and c3 activation. Interaction of daf with cell-associated C4b and C3b polypeptides interferes with their ability to catalyze the conversion of C2 and factor B to enzymatically active C2a and Bb and thereby prevents the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade. Inhibits complement activation by destabilizing and preventing the formation of C3 and C5 convertases, which prevents complement damage.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A7K6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7K6#function" }, { "database": "UniProtKB", "id": "ARBA00045541", "url": "https://www.uniprot.org/uniprotkb/ARBA00045541#function" }, { "database": "UniProtKB", "id": "A0A8V1AA63", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA63#function" }, { "database": "UniProtKB", "id": "A0A8V1AF18", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF18#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACZ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACZ9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "C4BPG", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACZ9", "locus": { "chromosome": "26", "start_pos": 2700893, "end_pos": 2693261, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027161", "url": "https://www.ensembl.org/id/ENSGALG00010027161" } ] } } ], "crossref": [ { "id": "A0A8V1ACZ9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1ACZ9", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00033", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00033", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000436", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000436", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035976", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035976", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050350", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050350", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051277", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051277", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A7K6", "url": "https://www.orthodb.org/?gene=A0A8V1A7K6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AA63", "url": "https://www.orthodb.org/?gene=A0A8V1AA63", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ACZ9", "url": "https://www.orthodb.org/?gene=A0A8V1ACZ9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AF18", "url": "https://www.orthodb.org/?gene=A0A8V1AF18", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19325", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19325", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19325:SF317", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19325:SF317", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45656", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45656", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45656:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45656:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00084", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00084", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-6798695", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-6807878", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6807878", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-977606", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-977606", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1A7K6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7K6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A7K6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7K6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AA63", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA63", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AA63-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA63-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ACZ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACZ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ACZ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACZ9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AF18", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF18", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AF18-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF18-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRRRNESVLLRERRKGLMQPPIAPEKVVRRRAAQSRAVPLGCSQHRAQPPERPEMAVGTALLWLSAALLALPGVCGDCPQPPRFAFAEPPGPTNSSYPVGTVLRYRCRPGYTGDRNKLPSVTCLPNSTWASDPDFCIGKSCGQPEIPNGNFHFSTNLQFGATINFTCKAGYRLVGKPTAQCILSGSDVVWDAVPYCEIIPCQPPPPIENGTLSSVHGEYTFGVAVTYSCKKGLSLIGNATIHCTMDDNLNGIWSGPAPECKDVRCEKPEVENAKNLNSFATEYTYGEKVSFECAPGHALSGAQTVTCDADNTWKPSLPSCDPRYCGSPPSIPSAELIGAAGNSFMAGTKLTYQCQPGFTTESGKSLEVTCLMDATWTSGSALCTRQQCTAPTIPNGIVNGDSFLFGTTVTFSCNAEYELKGSSSAKCVAVESGVEWDVKLPSCERQRSDVLCEQPPSIGNGVHNGTGGTAFPLGSVVVYSCNDGFNLVGDRAIQCLAKTQDRGVWSTPTPECRGGASSIIVGILPLLLAMLVMNF", "length": 535, "header": "tr|A0A8V1ACZ9-1|A0A8V1ACZ9_CHICK Isoform 1 of Complement component 4 binding protein, GPI-anchored OS=Gallus gallus OX=9031 GN=C4BPG PE=1 SV=1 CANONICAL=A0A8V1ACZ9-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A7K6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACZ9/entry#A0A8V1A7K6-1", "sequence": { "sequence": "MRRRNESVLLRERRKGLMQPPIAPEKVVRRRAAQSRAVPLGCSQHRAQPPERPEMAVGTALLWLSAALLALPGVCGDCPQPPRFAFAEPPGPTNSSYPVGTVLRYRCRPGYTGDRNKLPSVTCLPNSTWASDPDFCIGKSCGQPEIPNGNFHFSTNLQFGATINFTCKAGYRLVGKPTAQCILSGSDVVWDAVPYCEIIPCQPPPPIENGTLSSVHGEYTFGVAVTYSCKKGLSLIGNATIHCTMDDNLNGIWSGPAPECKDVRCEKPEVENAKNLNSFATEYTYGEKVSFECAPGHALSGAQTVTCDADNTWKPSLPSCDPRYCGSPPSIPSAELIGAAGNSFMAGTKLTYQCQPGFTTESGKSLEVTCLMDATWTSGSALCTRQQCTAPTIPNGIVNGDSFLFGTTVTFSCNAEYELKGSSSAKCVAVESGVEWDVKLPSCERQRSDVLCEQPPSIGNGVHNGTGGTAFPLGSVVVYSCNDGFNLVGDRAIQCLAKTQDRGVWSTPTPECRGILPLLLAMLVMNF", "length": 527, "header": "tr|A0A8V1A7K6-1|A0A8V1ACZ9_CHICK Computationally mapped isoform of Complement component 4 binding protein, GPI-anchored OS=Gallus gallus OX=9031 GN=C4BPG PE=1 SV=1 CANONICAL=A0A8V1ACZ9-1" }, "locus": { "chromosome": "26", "start_pos": 2699035, "end_pos": 2693479, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065851.1", "url": "https://www.ensembl.org/id/ENSGALT00010065851.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040117.1", "url": "https://www.ensembl.org/id/ENSGALP00010040117.1" } ] } }, { "isoform_ac": "A0A8V1AA63-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACZ9/entry#A0A8V1AA63-1", "sequence": { "sequence": "MRRRNESVLLRERRKGLMQPPIAPEKVVRRRAAQSRAVPLGCSQHRAQPPERPEMAVGTALLWLSAALLALPGVCGDCPQPPRFAFAEPPGPTNSSYPVGTVLRYRCRPGYTGDRNKLPSVTCLPNSTWASDPDFCIGKSCGQPEIPNGNFHFSTNLQFGATINFTCKAGYRLVGKPTAQCILSGSDVVWDAVPYCEIIPCQPPPPIENGTLSSVHGEYTFGVAVTYSCKKGLSLIGNATIHCTMDDNLNGIWSGPAPECKDVRCEKPEVENAKNLNSFATEYTYGEKVSFECAPGHALSGAQTVTCDADNTWKPSLPSCDPRYCGSPPSIPSAELIGAAGNSFMAGTKLTYQCQPGFTTESGKSLEVTCLMDATWTSGSALCTRQQCTAPTIPNGIVNGDSFLFGTTVTFSCNAEYELKGSSSAKCVAVESGVEWDVKLPSCESKEKLQKAIGIMAGTALVWLCGGGMGLCLGLFIQLAVKLRISVLTCTVWPYGPPRD", "length": 500, "header": "tr|A0A8V1AA63-1|A0A8V1ACZ9_CHICK Computationally mapped isoform of Complement component 4 binding protein, GPI-anchored OS=Gallus gallus OX=9031 GN=C4BPG PE=1 SV=1 CANONICAL=A0A8V1ACZ9-1" }, "locus": { "chromosome": "26", "start_pos": 2697760, "end_pos": 2693479, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065853.1", "url": "https://www.ensembl.org/id/ENSGALT00010065853.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040119.1", "url": "https://www.ensembl.org/id/ENSGALP00010040119.1" } ] } }, { "isoform_ac": "A0A8V1ACZ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACZ9/entry#A0A8V1ACZ9-1", "sequence": { "sequence": "MRRRNESVLLRERRKGLMQPPIAPEKVVRRRAAQSRAVPLGCSQHRAQPPERPEMAVGTALLWLSAALLALPGVCGDCPQPPRFAFAEPPGPTNSSYPVGTVLRYRCRPGYTGDRNKLPSVTCLPNSTWASDPDFCIGKSCGQPEIPNGNFHFSTNLQFGATINFTCKAGYRLVGKPTAQCILSGSDVVWDAVPYCEIIPCQPPPPIENGTLSSVHGEYTFGVAVTYSCKKGLSLIGNATIHCTMDDNLNGIWSGPAPECKDVRCEKPEVENAKNLNSFATEYTYGEKVSFECAPGHALSGAQTVTCDADNTWKPSLPSCDPRYCGSPPSIPSAELIGAAGNSFMAGTKLTYQCQPGFTTESGKSLEVTCLMDATWTSGSALCTRQQCTAPTIPNGIVNGDSFLFGTTVTFSCNAEYELKGSSSAKCVAVESGVEWDVKLPSCERQRSDVLCEQPPSIGNGVHNGTGGTAFPLGSVVVYSCNDGFNLVGDRAIQCLAKTQDRGVWSTPTPECRGGASSIIVGILPLLLAMLVMNF", "length": 535, "header": "tr|A0A8V1ACZ9-1|A0A8V1ACZ9_CHICK Isoform 1 of Complement component 4 binding protein, GPI-anchored OS=Gallus gallus OX=9031 GN=C4BPG PE=1 SV=1 CANONICAL=A0A8V1ACZ9-1" }, "locus": { "chromosome": "26", "start_pos": 2699035, "end_pos": 2693479, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065852.1", "url": "https://www.ensembl.org/id/ENSGALT00010065852.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040118.1", "url": "https://www.ensembl.org/id/ENSGALP00010040118.1" } ] } }, { "isoform_ac": "A0A8V1AF18-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACZ9/entry#A0A8V1AF18-1", "sequence": { "sequence": "MAVGTALLWLSAALLALPGVCGDCPQPPRFAFAEPPGPTNSSYPVGTVLRYRCRPGYTGDRNKLPSVTCLPNSTWASDPDFCIGKSCGQPEIPNGNFHFSTNLQFGATINFTCKAGYRLVGKPTAQCILSGSDVVWDAVPYCEIIPCQPPPPIENGTLSSVHGEYTFGVAVTYSCKKGLSLIGNATIHCTMDDNLNGIWSGPAPECKDVRCEKPEVENAKNLNSFATEYTYGEKVSFECAPGHALSGAQTVTCDADNTWKPSLPSCDPRYCGSPPSIPSAELIGAAGNSFMAGTKLTYQCQPGFTTESGKSLEVTCLMDATWTSGSALCTRQQCTAPTIPNGIVNGDSFLFGTTVTFSCNAEYELKGSSSAKCVAVESGVEWDVKLPSCERQRSDVLCEQPPSIGNGVHNGTGGTAFPLGSVVVYSCNDGFNLVGDRAIQCLAKTQDRGVWSTPTPECRGGASSIIVG", "length": 468, "header": "tr|A0A8V1AF18-1|A0A8V1AF18_CHICK Computationally mapped isoform of Complement component 4 binding protein, GPI-anchored OS=Gallus gallus OX=9031 GN=C4BPG PE=1 SV=1 CANONICAL=A0A8V1ACZ9-1" }, "locus": { "chromosome": "26", "start_pos": 2698847, "end_pos": 2693641, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065850.1", "url": "https://www.ensembl.org/id/ENSGALT00010065850.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040116.1", "url": "https://www.ensembl.org/id/ENSGALP00010040116.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 509, "start_aa": "Thr", "end_pos": 509, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr509", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 93, "start_aa": "Thr", "end_pos": 93, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr93", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-GGA-6798695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798695", "resource": "Reactome", "description": "Neutrophil degranulation" }, { "id": "R-GGA-6807878", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6807878", "resource": "Reactome", "description": "COPI-mediated anterograde transport" }, { "id": "R-GGA-977606", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-977606", "resource": "Reactome", "description": "Regulation of Complement cascade" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACZ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACZ9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACZ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACZ9" } ], "pmid": "" }, { "name": "complement activation, classical pathway", "id": "GO:0006958", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006958", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACZ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACZ9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 126, "end_pos": 128, "annotation": "n_glycosylation_sequon" }, { "start_pos": 164, "end_pos": 166, "annotation": "n_glycosylation_sequon" }, { "start_pos": 209, "end_pos": 211, "annotation": "n_glycosylation_sequon" }, { "start_pos": 238, "end_pos": 240, "annotation": "n_glycosylation_sequon" }, { "start_pos": 464, "end_pos": 466, "annotation": "n_glycosylation_sequon" }, { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" }, { "start_pos": 94, "end_pos": 96, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1ACZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACZ9" }, { "id": "PS50923", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50923" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Sushi", "eco_id": "ECO_0000259", "start_pos": 76, "end_pos": 138, "start_aa": "Gly", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 93, 509 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 126, "end_pos": 128 }, { "start_pos": 164, "end_pos": 166 }, { "start_pos": 209, "end_pos": 211 }, { "start_pos": 238, "end_pos": 240 }, { "start_pos": 464, "end_pos": 466 }, { "start_pos": 5, "end_pos": 7 }, { "start_pos": 94, "end_pos": 96 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1ACR6-1", "uniprot_ac": "A0A8V1ACR6", "uniprot_id": "A0A8V1ACR6_CHICK", "mass": { "chemical_mass": 34028.0, "monoisotopic_mass": 34028.0 }, "refseq": {}, "gene_names": [ { "name": "SPDEF", "type": "recommended", "evidence": [ { "id": "A0A8V1ACR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACR6" } ] } ], "protein_names": [ { "name": "SAM pointed domain-containing Ets transcription factor", "type": "recommended", "evidence": [ { "id": "A0A8V1ACR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACR6/entry#names_and_taxonomy" } ] }, { "name": "Prostate epithelium-specific Ets transcription factor", "type": "synonym", "evidence": [ { "id": "A0A8V1ACR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACR6/entry#names_and_taxonomy" } ] }, { "name": "Prostate-derived Ets factor", "type": "synonym", "evidence": [ { "id": "A0A8V1ACR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACR6/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "May function as an androgen-independent transactivator of the prostate-specific antigen (PSA) promoter. Binds to 5'-GGAT-3' DNA sequences. May play a role in the regulation of the prostate gland and/or prostate cancer development. Acts as a transcriptional activator for SERPINB5 promoter.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACR6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACR6#function" }, { "database": "UniProtKB", "id": "ARBA00057194", "url": "https://www.uniprot.org/uniprotkb/ARBA00057194#function" }, { "database": "UniProtKB", "id": "A0A8V1A7R9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7R9#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACR6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACR6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SPDEF", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACR6", "locus": { "chromosome": "26", "start_pos": 4400199, "end_pos": 4387211, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010026109", "url": "https://www.ensembl.org/id/ENSGALG00010026109" } ] } } ], "crossref": [ { "id": "A0A8V1ACR6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1ACR6", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd08532", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08532", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000418", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000418", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003118", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003118", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013761", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013761", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036388", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036388", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036390", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036390", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046328", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046328", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:428271", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428271", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1A7R9", "url": "https://www.orthodb.org/?gene=A0A8V1A7R9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ACR6", "url": "https://www.orthodb.org/?gene=A0A8V1ACR6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11849", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11849", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11849:SF182", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11849:SF182", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00178", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00178", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02198", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02198", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1A7R9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7R9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A7R9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7R9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ACR6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACR6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ACR6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACR6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "METAGGLSTGSMGSPSPPGTPFCLHYFDMLYSEDVAWAAKGMGETSQSGTPGGRGEVKKEPEQCPIIDSQGLGLGGDGELQGGLPLEEHSLEQMQSMVVGEVLKDIETACKLLNIAADPADWSPGNVQKWILWTEHQYRLPQLGKSFQELSGKELCAMSEEQFCQRSPLCGDVLHAHLDIWKSAAWMKEKAAPGDVRYCGGDSGWADSEVDSSCAGQPIHLWQFLKELLLKPHNYGRFIRWLNKEKGIFKIEDSAQVARLWGIRKNRPAMNYDKLSRSIRQYYKKGIIRKPDISQRLVYQFVHPL", "length": 305, "header": "tr|A0A8V1ACR6-1|A0A8V1ACR6_CHICK Isoform 1 of SAM pointed domain-containing Ets transcription factor OS=Gallus gallus OX=9031 GN=SPDEF PE=3 SV=1 CANONICAL=A0A8V1ACR6-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A7R9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACR6/entry#A0A8V1A7R9-1", "sequence": { "sequence": "MGSPSPPGTPFCLHYFDMLYSEDVAWAAKGMGETSQSGTPGGRGEVKKEPEQCPIIDSQGLGLGGDGELQGGLPLEEHSLEQMQSMVVGEVLKDIETACKLLNIAADPADWSPGNVQKWILWTEHQYRLPQLGKSFQELSGKELCAMSEEQFCQRSPLCGDVLHAHLDIWKSAAWMKEKAAPGDVRYCGGDSGWADSEVDSSCAGQPIHLWQFLKELLLKPHNYGRFIRWLNKEKGIFKIEDSAQVARLWGIRKNRPAMNYDKLSRSIRQYYKKGIIRKPDISQRLVYQFVHPL", "length": 294, "header": "tr|A0A8V1A7R9-1|A0A8V1ACR6_CHICK Computationally mapped isoform of SAM pointed domain-containing Ets transcription factor OS=Gallus gallus OX=9031 GN=SPDEF PE=3 SV=1 CANONICAL=A0A8V1ACR6-1" }, "locus": { "chromosome": "26", "start_pos": 4398130, "end_pos": 4396316, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063615.1", "url": "https://www.ensembl.org/id/ENSGALT00010063615.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039267.1", "url": "https://www.ensembl.org/id/ENSGALP00010039267.1" } ] } }, { "isoform_ac": "A0A8V1ACR6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACR6/entry#A0A8V1ACR6-1", "sequence": { "sequence": "METAGGLSTGSMGSPSPPGTPFCLHYFDMLYSEDVAWAAKGMGETSQSGTPGGRGEVKKEPEQCPIIDSQGLGLGGDGELQGGLPLEEHSLEQMQSMVVGEVLKDIETACKLLNIAADPADWSPGNVQKWILWTEHQYRLPQLGKSFQELSGKELCAMSEEQFCQRSPLCGDVLHAHLDIWKSAAWMKEKAAPGDVRYCGGDSGWADSEVDSSCAGQPIHLWQFLKELLLKPHNYGRFIRWLNKEKGIFKIEDSAQVARLWGIRKNRPAMNYDKLSRSIRQYYKKGIIRKPDISQRLVYQFVHPL", "length": 305, "header": "tr|A0A8V1ACR6-1|A0A8V1ACR6_CHICK Isoform 1 of SAM pointed domain-containing Ets transcription factor OS=Gallus gallus OX=9031 GN=SPDEF PE=3 SV=1 CANONICAL=A0A8V1ACR6-1" }, "locus": { "chromosome": "26", "start_pos": 4398130, "end_pos": 4387252, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063618.1", "url": "https://www.ensembl.org/id/ENSGALT00010063618.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039269.1", "url": "https://www.ensembl.org/id/ENSGALP00010039269.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 50, "start_aa": "Thr", "end_pos": 50, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr50", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:428271", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428271", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACR6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACR6" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACR6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACR6" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACR6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACR6" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACR6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACR6" } ], "pmid": "" }, { "name": "positive regulation of apoptotic process", "id": "GO:0043065", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043065", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACR6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACR6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACR6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACR6" } ], "pmid": "" }, { "name": "sequence-specific DNA binding", "id": "GO:0043565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043565", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACR6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACR6" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACR6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACR6" } ], "pmid": "" }, { "name": "sequence-specific double-stranded DNA binding", "id": "GO:1990837", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990837", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACR6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACR6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACR6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACR6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1ACR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACR6" }, { "id": "PS50061", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50061" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "ETS", "eco_id": "ECO_0000259", "start_pos": 219, "end_pos": 302, "start_aa": "Ile", "end_aa": "Val", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1ACR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACR6" }, { "id": "PS51433", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51433" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PNT", "eco_id": "ECO_0000259", "start_pos": 101, "end_pos": 185, "start_aa": "Glu", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 50 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AD88-1", "uniprot_ac": "A0A8V1AD88", "uniprot_id": "A0A8V1AD88_CHICK", "mass": { "chemical_mass": 81797.0, "monoisotopic_mass": 81797.0 }, "refseq": {}, "gene_names": [ { "name": "ECM2", "type": "recommended", "evidence": [ { "id": "A0A8V1AD88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD88" } ] } ], "protein_names": [ { "name": "Extracellular matrix protein 2", "type": "synonym", "evidence": [ { "id": "A0A8V1AD88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD88/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AD88", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD88" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ECM2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD88", "locus": { "chromosome": "12", "start_pos": 3562934, "end_pos": 3544355, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027198", "url": "https://www.ensembl.org/id/ENSGALG00010027198" } ] } } ], "crossref": [ { "id": "A0A8V1AD88", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AD88", "database": "AlphaFoldDB", "categories": [] }, { "id": "415953", "url": "https://www.ncbi.nlm.nih.gov/gene/415953", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001007", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001007", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003591", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003591", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043184", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043184", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:415953", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415953", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MTMYNRA", "url": "https://omabrowser.org/oma/group/MTMYNRA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A7U8", "url": "https://www.orthodb.org/?gene=A0A8V1A7U8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AD88", "url": "https://www.orthodb.org/?gene=A0A8V1AD88", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AFB1", "url": "https://www.orthodb.org/?gene=A0A8V1AFB1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46544", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46544", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46544:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46544:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00093", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00093", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13855", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13855", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1A7U8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7U8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A7U8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7U8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AD88", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD88", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AD88-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD88-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFB1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFB1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFB1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFB1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAHCSRTLSKPYKNMQSSSFIYYFLLLSLCIDLSHNETSAALRRQRRRMRHRGLRRSSYAGRRFLRQPRMKLPAPAAPSIPLINIDDGVMGVFDSLIGLGGHESSYNVLPGKKGQCTANGMIMFDKAVWSPKPCITCLCSKGEVICDTTMCHPLKCPQTIIPAGECCPVCSDTVSPLDSNIVSLDDITELSGDSPEPNDLDNNPNVLPSSRTQTEKGELLRTEVVEIKENEVHKKDEKRRKKKGKKNRQKYKAHQKEEKPDGRKDEERRRLFEEEELQLEKELIRKRQGVRTRERDSEEQYESDEDDGTFPIPVPPIEAPPLPAACSTSESTVSCINAKLTQIPPISDPDLTSLDLTGNIITTISNEAFNGIPNLEWIDLSKNNISSSGIGPHAFKTLKKLKRLYLDGNMLVHIPSELPSTLEEIKINDNQLHAIDEDALQGLKNLVTLELEGNKLSEANVSPLAFYPLKSLSYLRLGRNKFRIIPQGLPTTLEELYLENNQIEEVSEICFNHTRKINVIVLKHNKLEEHRIAPLAWINQENLESIDLSYNKLYHVPSYLPKSLLHLILIGNQIERIPGYVFGHMKPGLEYLYLSFNKLTDDGIDPVSFFGAYHSLRELFLDHNDLKSVPFGIEEMRKLRFLRLNNNKIRTVPPERICRTHLHDDDVHYNSEEDEGEDSRLEHVHLENNYINTRQLSPHSFSCIRSYCSVVLKPQKTK", "length": 718, "header": "tr|A0A8V1AD88-1|A0A8V1AD88_CHICK Isoform 1 of Extracellular matrix protein 2 OS=Gallus gallus OX=9031 GN=ECM2 PE=1 SV=1 CANONICAL=A0A8V1AD88-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A7U8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD88/entry#A0A8V1A7U8-1", "sequence": { "sequence": "MQSSSFIYYFLLLSLCIDLSHNETSAALRRQRRRMRHRGLRRSSYAGRRFLRQPRMKLPAPAAPSIPLINIDDGVMGVFDSLIGLGGHESSYNVLPGKKGQCTANGMIMFDKAVWSPKPCITCLCSKGEVICDTTMCHPLKCPQTIIPAGECCPVCSDTVSPLDSNIVSLDDITELSGDSPEPNDLDNNPNVLPSSRTQTEKGELLRTEVVEIKENEVHKKDEKRRKKKGKKNRQKYKAHQKEEKPDGRKDEERRRLFEEEELQLEKELIRKRQGVRTRERDSEEQYESDEDDGTFPIPVPPIEAPPLPAACSTSESTVSCINAKLTQIPPISDPDLTSLDLTGNIITTISNEAFNGIPNLEWIDLSKNNISSSGIGPHAFKTLKKLKRLYLDGNMLVHIPSELPSTLEEIKINDNQLHAIDEDALQGLKNLVTLELEGNKLSEANVSPLAFYPLKSLSYLRLGRNKFRIIPQGLPTTLEELYLENNQIEEVSEICFNHTRKINVIVLKHNKLEEHRIAPLAWINQENLESIDLSYNKLYHVPSYLPKSLLHLILIGNQIERIPGYVFGHMKPGLEYLYLSFNKLTDDGIDPVSFFGAYHSLRELFLDHNDLKSVPFGIEEMRKLRFLRLNNNKIRTVPPERICRTHLHDDDVHYNSEEDEGEDSRLEHVHLENNYINTRQLSPHSFSCIRSYCSVVLKPQKTK", "length": 704, "header": "tr|A0A8V1A7U8-1|A0A8V1AD88_CHICK Computationally mapped isoform of Extracellular matrix protein 2 OS=Gallus gallus OX=9031 GN=ECM2 PE=1 SV=1 CANONICAL=A0A8V1AD88-1" }, "locus": { "chromosome": "12", "start_pos": 3561029, "end_pos": 3548425, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065941.1", "url": "https://www.ensembl.org/id/ENSGALT00010065941.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040207.1", "url": "https://www.ensembl.org/id/ENSGALP00010040207.1" } ] } }, { "isoform_ac": "A0A8V1AD88-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD88/entry#A0A8V1AD88-1", "sequence": { "sequence": "MAHCSRTLSKPYKNMQSSSFIYYFLLLSLCIDLSHNETSAALRRQRRRMRHRGLRRSSYAGRRFLRQPRMKLPAPAAPSIPLINIDDGVMGVFDSLIGLGGHESSYNVLPGKKGQCTANGMIMFDKAVWSPKPCITCLCSKGEVICDTTMCHPLKCPQTIIPAGECCPVCSDTVSPLDSNIVSLDDITELSGDSPEPNDLDNNPNVLPSSRTQTEKGELLRTEVVEIKENEVHKKDEKRRKKKGKKNRQKYKAHQKEEKPDGRKDEERRRLFEEEELQLEKELIRKRQGVRTRERDSEEQYESDEDDGTFPIPVPPIEAPPLPAACSTSESTVSCINAKLTQIPPISDPDLTSLDLTGNIITTISNEAFNGIPNLEWIDLSKNNISSSGIGPHAFKTLKKLKRLYLDGNMLVHIPSELPSTLEEIKINDNQLHAIDEDALQGLKNLVTLELEGNKLSEANVSPLAFYPLKSLSYLRLGRNKFRIIPQGLPTTLEELYLENNQIEEVSEICFNHTRKINVIVLKHNKLEEHRIAPLAWINQENLESIDLSYNKLYHVPSYLPKSLLHLILIGNQIERIPGYVFGHMKPGLEYLYLSFNKLTDDGIDPVSFFGAYHSLRELFLDHNDLKSVPFGIEEMRKLRFLRLNNNKIRTVPPERICRTHLHDDDVHYNSEEDEGEDSRLEHVHLENNYINTRQLSPHSFSCIRSYCSVVLKPQKTK", "length": 718, "header": "tr|A0A8V1AD88-1|A0A8V1AD88_CHICK Isoform 1 of Extracellular matrix protein 2 OS=Gallus gallus OX=9031 GN=ECM2 PE=1 SV=1 CANONICAL=A0A8V1AD88-1" }, "locus": { "chromosome": "12", "start_pos": 3561029, "end_pos": 3544443, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065942.1", "url": "https://www.ensembl.org/id/ENSGALT00010065942.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040208.1", "url": "https://www.ensembl.org/id/ENSGALP00010040208.1" } ] } }, { "isoform_ac": "A0A8V1AFB1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD88/entry#A0A8V1AFB1-1", "sequence": { "sequence": "MTLSKPYKNMQSSSFIYYFLLLSLCIDLSHNETSAALRRQRRRMRHRGLRRSSYAGRRFLRQPRMKLPAPAAPSIPLINIDDGVMGVFDSLIGLGGHESSYNVLPGKKGQCTANGMIMFDKAVWSPKPCITCLCSKGEVICDTTMCHPLKCPQTIIPAGECCPVCSDTVSPLDSNIVSLDDITELSGDSPEPNDLDNNPNVLPSSRTQTEKGELLRTEVVEIKENEVHKKDEKRRKKKGKKNRQKYKAHQKEEKPDGRKDEERRRLFEEEELQLEKELIRKRQGVRTRERDSEEQYESDEDDGTFPIPVPPIEAPPLPAACSTSESTVSCINAKLTQIPPISDPDLTSLDLTGNIITTISNEAFNGIPNLEWIDLSKNNISSSGIGPHAFKTLKKLKRLYLDGNMLVHIPSELPSTLEEIKINDNQLHAIDEDALQGLKNLVTLELEGNKLSEANVSPLAFYPLKSLSYLRLGRNKFRIIPQGLPTTLEELYLENNQIEEVSEICFNHTRKINVIVLKHNKLEEHRIAPLAWINQENLESIDLSYNKLYHVPSYLPKSLLHLILIGNQIERIPGYVFGHMKPGLEYLYLSFNKLTDDGIDPVSFFGAYHSLRELFLDHNDLKSVPFGIEEMRKLRFLRLNNNKIRTVPPERICRTHLHDDDVHYNSEEDEGEDSRLEHVHLENNYINTRQLSPHSFSCIRSYCSVVLKPQKTK", "length": 713, "header": "tr|A0A8V1AFB1-1|A0A8V1AFB1_CHICK Computationally mapped isoform of Extracellular matrix protein 2 OS=Gallus gallus OX=9031 GN=ECM2 PE=1 SV=1 CANONICAL=A0A8V1AD88-1" }, "locus": { "chromosome": "12", "start_pos": 3561029, "end_pos": 3546945, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065940.1", "url": "https://www.ensembl.org/id/ENSGALT00010065940.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040206.1", "url": "https://www.ensembl.org/id/ENSGALP00010040206.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:415953", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415953", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2M482-1", "protein_name": "Extracellular matrix protein 2", "gene_name": "Ecm2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MKHAVLFCLILLIIFQTDCEQTTRKQRRKEHQRRLRKSSSFHHTANRQPEIQPTTAASEARLPAVNPVYSVEENLEFLLSSPGAESSYSVLPGKKGHCFVKGMIMYNKAVWSPEPCSTCLCSNGRVLCDETVCHPKACPYTIKPEGECCPICSDAEQRESINILHKQVPPPQMEMDQVVIKAALQSEEDEEEIKEHMDHKKETSGPTELHSDEERAEGKPRPEVEGQSAHEPLYHGQGEGEDDEEETEREGEREEEEEEDVRGDVFRMPSRLMPGAPRGRPRLPGSCVLSYRTISCIHASFTQIPPITAPEVTSLELAGNSIISIPDEAFNGLPNLERIDLSRNNITSSGIGPKAFKFLKKLMRLNMDGNNLVRIPSELPSTLEELKINDNNLQAIDEESLSDLNQLVTLELEGNNLSEINVNPLAFKSLKSLSYLRLGKNKFRIIPQGLPASIEELYLENNQIEEITEICFNHTRKINMIVLRYNKIEESRIAPLAWINQENLESIDLSYNKLYHVPSYLPKSLLHLVLIGNQIERIPGYVFGHMEPGLEYLYLSFNRLADDGVDLVSFYGAYHSLRELFLDHNDLKSIPPGIQDMKALHFLRLNNNKIRNILPEQICNVEEDEDSALEHLHLENNYIRTREISSYAFSCIRLYSSIVLKPQNIK", "length": 666 }, "evidence": [ { "id": "A0A8V1AD88", "url": "https://omabrowser.org/oma/group/A0A8V1AD88/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8D0X6M2-1", "protein_name": "Extracellular matrix protein 2", "gene_name": "ECM2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MKFSGLYCFLLLLICQTDYGQNEETSRKQRRKMYYRRLRKSSLPTHRSSRQLGIQQMIATPAATLPMVNLDYSTEEKFESFLSVPGVESSYNVLPEKKGHCLANGMIMYNRAVWSPEPCTTCLCSNGRVLCDETKCHPQLCSRTVIPEGECCPVCSDTASDLLLSSIALNDRTEFSGDSSEQRERNNLLHKQQPPSWVEMDQVMRKEQHQYEEDEEEIKQVEEKEQKKNTPRRGDWGIPSKEGQSREAGEQRPAGEGRQAHQHRNPARETEEAEEEDEEDEDEDLDEDTIRGDVFRMSSQRRVPATPRGTPPLPSRCSLSYKTISCISADLTQIPPLRAPEITSLELVGNSITSIPDEAFNGLPNLERLDLSKNNITSSGIGPKAFKLLKNLMRLNMDGNNLVAIPSGLPSTLEELKINDNNLQVIDEESLSDLNQLVTLELEGNNLSEINVNSLAFKPLKSLSYLRLGRNKFRIIPQGLPASIEELYLENNQIEEITELCFNHTRKINVIVLRYNKIEENRIAPLAWINQENLESIDLSYNKLYHVPSYLPKSLLHLVLIGNLIERIPGYVFGHMEPGLEYLYLSFNKLVDDSIDRVSFYGAYHSLRELFLDHNELKSIPPGVQEMKALHFLRLNNNKIRNILPEQICNVEEDGDSTLEHLHLENNYIKTREISSYAFSCIRSYSSIILKPQNIK", "length": 696 }, "evidence": [ { "id": "A0A8V1AD88", "url": "https://omabrowser.org/oma/group/A0A8V1AD88/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O94769-1", "protein_name": "Extracellular matrix protein 2", "gene_name": "ECM2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKIAVLFCFFLLIIFQTDFGKNEEIPRKQRRKIYHRRLRKSSTSHKHRSNRQLGIQQTTVFTPVARLPIVNFDYSMEEKFESFSSFPGVESSYNVLPGKKGHCLVKGITMYNKAVWSPEPCTTCLCSDGRVLCDETMCHPQRCPQTVIPEGECCPVCSATVSYSLLSGIALNDRNEFSGDSSEQREPTNLLHKQLPPPQVGMDRIVRKEALQSEEDEEVKEEDTEQKRETPESRNQGQLYSEGDSRGGDRKQRPGEERRLAHQQQRQGREEEEDEEEEGEEGEEDEEDEEDPVRGDMFRMPSRSPLPAPPRGTLRLPSGCSLSYRTISCINAMLTQIPPLTAPQITSLELTGNSIASIPDEAFNGLPNLERLDLSKNNITSSGIGPKAFKLLKKLMRLNMDGNNLIQIPSQLPSTLEELKVNENNLQAIDEESLSDLNQLVTLELEGNNLSEANVNPLAFKPLKSLAYLRLGKNKFRIIPQGLPGSIEELYLENNQIEEITEICFNHTRKINVIVLRYNKIEENRIAPLAWINQENLESIDLSYNKLYHVPSYLPKSLLHLVLLGNQIERIPGYVFGHMEPGLEYLYLSFNKLADDGMDRVSFYGAYHSLRELFLDHNDLKSIPPGIQEMKALHFLRLNNNKIRNILPEEICNAEEDDDSNLEHLHLENNYIKIREIPSYTFSCIRSYSSIVLKPQNIK", "length": 699 }, "evidence": [ { "id": "A0A8V1AD88", "url": "https://omabrowser.org/oma/group/A0A8V1AD88/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5FW85-1", "protein_name": "Extracellular matrix protein 2", "gene_name": "Ecm2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKLAVLFCFILLIVLQTDCERGTRRQRRRMHQRRLRKSSSFHLRANRQLEVQQTTAAPDARLPTANSDYSVEENIESLLSNLGVESSYSVLPGKKGYCFVKGMIMYNKAVWSPEPCTTCLCSNGRVLCDETECHPKACPYTIKPEGECCPICSDAEQESINKLHKQVPPPQMEMDQVAIKEALQSEEDEEIAEGHKEHKKETSVPTKIHGDGERTERKLRPEKEGRSAHQPLYHGRREEEESKEETEREGEEEEEEEEEEEEDAIRGDVFRMSSRVIPGTPRGRPRLPRSCSLSYRTISCVHADFTEIPPITAPEVTNLELVGNSIISIPDEAFNGLPNLERLDLSRNNITSSGIGPKAFKSLKKLMRLNMDGNNLVHIPSDLPSTLEELKINDNNLQAIDEKSLSDLNQLVTLELEGNNLSEINVDPLAFQSLESLSYLRLGRNKFRIIPQGLPASTEELYLENNQIEEITEICFNHTRKITMIILRYNKIEESRIAPLAWINQENLESIDLSYNKLYHVPSYLPKSLLHLVLIGNQIDRIPGYVFGHMQPGLEYLYLSFNRLSDDGVDLVSFYGAYHSLRELFLDHNDFKSIPPGIQDMKALHFLRLNNNKIRNIHPEQICNAEEDEDSALEHLHLENNYIRTREISSYAFSCIRLYSSIVLKPQHIK", "length": 670 }, "evidence": [ { "id": "A0A8V1AD88", "url": "https://omabrowser.org/oma/group/A0A8V1AD88/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "heparin binding", "id": "GO:0008201", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008201", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AD88", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD88" } ], "pmid": "" }, { "name": "collagen V binding", "id": "GO:0070052", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070052", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AD88", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD88" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "extracellular matrix organization", "id": "GO:0030198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030198", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AD88", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD88" } ], "pmid": "" }, { "name": "positive regulation of cell-substrate adhesion", "id": "GO:0010811", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010811", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AD88", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD88" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "extracellular matrix", "id": "GO:0031012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031012", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AD88", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD88" } ], "pmid": "" }, { "name": "interstitial matrix", "id": "GO:0005614", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005614", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AD88", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD88" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 36, "end_pos": 38, "annotation": "n_glycosylation_sequon" }, { "start_pos": 384, "end_pos": 386, "annotation": "n_glycosylation_sequon" }, { "start_pos": 460, "end_pos": 462, "annotation": "n_glycosylation_sequon" }, { "start_pos": 512, "end_pos": 514, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AD88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD88" }, { "id": "PS50184", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50184" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "VWFC", "eco_id": "ECO_0000259", "start_pos": 114, "end_pos": 171, "start_aa": "Gly", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 36, "end_pos": 38 }, { "start_pos": 384, "end_pos": 386 }, { "start_pos": 460, "end_pos": 462 }, { "start_pos": 512, "end_pos": 514 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1ACU5-1", "uniprot_ac": "A0A8V1ACU5", "uniprot_id": "A0A8V1ACU5_CHICK", "mass": { "chemical_mass": 179937.0, "monoisotopic_mass": 179937.0 }, "refseq": {}, "gene_names": [ { "name": "IQGAP3", "type": "recommended", "evidence": [ { "id": "A0A8V1ACU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACU5" } ] } ], "protein_names": [ { "name": "IQ motif containing GTPase activating protein 3", "type": "synonym", "evidence": [ { "id": "A0A8V1ACU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACU5/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACU5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACU5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "IQGAP3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACU5", "locus": { "chromosome": "25", "start_pos": 475645, "end_pos": 441655, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028108", "url": "https://www.ensembl.org/id/ENSGALG00010028108" } ] } } ], "crossref": [ { "id": "cd23767", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd23767", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000048", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000048", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000593", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000593", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001202", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001202", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001715", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001715", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001936", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001936", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008936", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008936", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023152", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023152", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036872", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036872", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A7V1", "url": "https://www.orthodb.org/?gene=A0A8V1A7V1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ACP2", "url": "https://www.orthodb.org/?gene=A0A8V1ACP2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ACU5", "url": "https://www.orthodb.org/?gene=A0A8V1ACU5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AHT3", "url": "https://www.orthodb.org/?gene=A0A8V1AHT3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AHV2", "url": "https://www.orthodb.org/?gene=A0A8V1AHV2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AHW1", "url": "https://www.orthodb.org/?gene=A0A8V1AHW1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AJN1", "url": "https://www.orthodb.org/?gene=A0A8V1AJN1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AJQ3", "url": "https://www.orthodb.org/?gene=A0A8V1AJQ3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14149", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14149", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14149:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14149:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00307", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00307", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00612", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00612", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00616", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00616", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03836", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03836", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-5626467", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5626467", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-8980692", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8980692", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9013026", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013026", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9013106", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013106", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9013149", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013149", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9013406", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013406", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1A7V1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7V1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A7V1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7V1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ACP2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACP2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ACP2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACP2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ACU5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACU5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ACU5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACU5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHT3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHT3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHT3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHT3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHV2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHV2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHV2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHV2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHW1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHW1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHW1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHW1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJN1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJN1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJN1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJN1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJQ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJQ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJQ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJQ3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MYDVTGTQPGAAVLGFGAVRGTAARDPPGTAPAAVPAAGERPSAEQMDEQRRQNVAYQYLCRLEEAKRWMEACLGEELPPPTELEENLRNGVLLARLGHRFAPDAVPPARIYDPQQTRYRTSGLHFRHTDNINHWRCAMSRLGLPSIFHPETTDIYDKKNMPRAVYCLHALSLYLFKLGLAPQIQDLSGKVDFTEEEISDAGRELEKLGLQLPAFGRIGGILADELSLDEAAVHAAVLAINVAVERGDVGRTMEALLHPGAMLRGLRTALAAAYQDVLRGAQREKGGGREWVRTREGDIYTHCLTQAEIQENISRVNVHAALEEVDDAVQRGDALLLHRALQDPALSLPHLQRDNLQLCLEQLRAQRQQKALVGGLQWGAVQHGSCSPDPIPAPSAVLRAVSAINAAIRRGIPAATLQALLEPSAQLPAAFPHAAALYQHQLALLQRQHPRVGLLQEELFVAVEMLSAVALVNRAVDAGNPEELWGGLLSPALGLSGVEEENAQRYFDALLQLKEQLRKEGAEFLSWTDIQDSVNATNASVQDETDRLLAVQRINAALRHADPQRTLAALLLPAAALPDVALPNAGRYHRVLSRARAAKAQVWGGGPWVALGTAAINQAIREGRAAQTLRVLRNPDVALRGVVDACAALYQEELQALAATKKPRGSTKPRWVRHRLRDGSEFYLSLQSFEGSWERPCDGELCATHLSREEIQSVITRVTAAHDRQRLWASNMAAVVGLQALLRGFLARRRFVALRRRHTAAVRIQASWRGYRQRKAYLQRLHYLRAHGDAVVKVGLLCLHPRLTPLCHRQGMRRIGAVVKIQAFVRANKARGDYRMLGDPPLGAVRRFIHVLEQNQSDFVEEAEVLRLREEVAKRIRASQQLEGDLSLMDIQIGLLVRNPRHEVVSQCRKLTRKNREQLSELMCLDKQKGLKSLSKEKRQKLEAYQHLFYLLQTQPTYLARLLFQVPQNKSTAFLQPVVFTLYSYASHPREGYLLLQLFKAALQEEIRCRVERIHDVLTGNAAVIRMVVGFYRSARGRSALRHILGRPVREVLRDATLSIRTDPVDIYKAWVNQAESQSGQRSGLPYEVSPEQALCHPEVRRRLDASVRALLAVTEKFVSAITSSVDQIPYGMRYVAKTLRASLAEKFPEASEEELDKVVGNLLYYRFMNPAVVAPDGFDVVDVSAGAALRPEQRRSLGSIAKVLQHAAARKAFEGENGHLCGANRYLEETHCKFRRFIAAACRVPEPKERFNVDEYSEMVAVAKPVIYITAGELIATHRLLLEHRDSIAPDPGDPLHELLEDLGELPTLQALVGTYGALPSQPSSERALPPSVAPSTKQMLVDVIQCQPGGSLAEILRTPASELEEASHHHLMRRRALWDSQTPTKLNRHRSLVANSQLSVEEKKQRIVRNLRRLEVLGLVDAAQHYQGLINELAKDIRNQRRYRQHRREELLKLRQTLRALDAKTLFYEEQIDYYNQYIRSCLHGLAVLRGPFSFRANGKGKKLQPLRYTAARLLEMGVLLEIQDLPASQFRNVIFDIVPCREPGRFQVKAQFMGIDMERFQLHYQDLLQLQYEGVAVMKMFGKAKVNVNLLLFLLNKKFFKK", "length": 1605, "header": "tr|A0A8V1ACU5-1|A0A8V1ACU5_CHICK Isoform 1 of IQ motif containing GTPase activating protein 3 OS=Gallus gallus OX=9031 GN=IQGAP3 PE=4 SV=1 CANONICAL=A0A8V1ACU5-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A7V1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACU5/entry#A0A8V1A7V1-1", "sequence": { "sequence": "MDGAERPQWERPSAEQMDEQRRQNVAYQYLCRLEEAKRWMEACLGEELPPPTELEENLRNGVLLARLGHRFAPDAVPPARIYDPQQTRYRTSGLHFRHTDNINHWRCAMSRLGLPSIFHPETTDIYDKKNMPRAVYCLHALSLYLFKLGLAPQIQDLSGKVDFTEEEISDAGRELEKLGLQLPAFGRIGGILADELSLDEAAVHAAVLAINVAVERGDVGRTMEALLHPGAMLRGLRTALAAAYQDVLRGAQREKGGGREWVRTREGGDIYTHCLTQAEIQENISRVNVHAALEEVDDAVQRGDALLLHRALQDPALSLPHLQRDNLQLCLEQLRAQRQQKALELGYVELLDEEEVAVGIQVANERGEEERAMLRAVSAINAAIRRGIPAATLQALLEPSAQLPAAFPHAAALYQHQLALLQRQHPRGELLQEELFVAVEMLSAVALVNRAVDAGNPEELWGGLLSPALGLSGVEEENAQRYFDALLQLKEQLRKEGAEFLSWTDIQDSVNATNASVQDETDRLLAVQRINAALRHADPQRTLAALLLPAAALPDVALPNAGRYHRVLSRARAAKAQVGDDGAELWWEEIERGVRAANEETAAVRRMALGTAAINQAIREGRAAQTLRVLRNPDVALRGVVDACAALYQEELQALAATKKPRGTARGWDPPLQGGRSFYLSLQSFEGSWERPCDGELCATHLSREEIQSVITRVTAAHDRQRLWASNMAAVVGLQALLRGFLARRRFVALRRRHTAAVRIQASWRGYRQRKAYLQRLHYLRAHGDAVVKVGLLCLHPRLTPLCHRQGMRRVPSSVVKIQAFVRANKARGDYRMLVHERSPPLGAVRRFIHVLEQNQSDFVEEAEVLRLREEVAKRIRASQQLEGDLSLMDIQIGLLVRNPRHEVVSQCRKLTRKNREQLSELMCLDKQKGLKSLSKEKRQKLEAYQHLFYLLQTQPTYLARLLFQVPQNKSTAFLQPVVFTLYSYASHPREGYLLLQLFKAALQEEIRCRVERIHDVLTGNAAVIRMVVGFYRSARGRSALRHILGRPVREVLRDATLSIRTDPVDIYKAWVNQAESQSGQRSGLPYEVSPEQALCHPEVRRRLDASVRALLAVTEKFVSAITSSVDQIPYGMRYVAKTLRASLAEKFPEASEEELDKVVGNLLYYRFMNPAVVAPDGFDVVDVSAGAALRPEQRRSLGSIAKVLQHAAARKAFEGENGHLCGANRYLEETHCKFRWAPGGRAEGFQGPFALSSAPPPAPLCHSPLTRTAQLLLEHRDSIAPDPGDPLHELLEDLGELPTLQALVGTYGTLSREALGMYGGGAERALPPSVAPSTKQMLVDVIQCQPGGSLAEILRTPASELEEASHHHLMRRRALWDSQTPTKLNRHRSLVANSQLSVEEKKQRIVRNLRRLEVLGLVDAAQHYQGLINELAKDIRNQRRYRQHRREELLKLRQTLRALDAKTLFYEEQIDYYNQYIRSCLHGLAASNKANGKGKKLQPLRYTAARLLEMGVLLEIQDLPASQFRNVIFDIVPCREPGRFQVKAQFMGIDMERFQLHYQDLLQLQYEGVAVMKMFGKAKVNVNLLLFLLNKKFFKK", "length": 1597, "header": "tr|A0A8V1A7V1-1|A0A8V1ACU5_CHICK Computationally mapped isoform of IQ motif containing GTPase activating protein 3 OS=Gallus gallus OX=9031 GN=IQGAP3 PE=4 SV=1 CANONICAL=A0A8V1ACU5-1" }, "locus": { "chromosome": "25", "start_pos": 474899, "end_pos": 442312, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068288.1", "url": "https://www.ensembl.org/id/ENSGALT00010068288.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042031.1", "url": "https://www.ensembl.org/id/ENSGALP00010042031.1" } ] } }, { "isoform_ac": "A0A8V1ACP2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACU5/entry#A0A8V1ACP2-1", "sequence": { "sequence": "PPRGTRGGGERPSAEQMDEQRRQNVAYQYLCRLEEAKRWMEACLGEELPPPTELEENLRNGVLLARLGHRFAPDAVPPARIYDPQQTRYRTSGLHFRHTDNINHWRCAMSRLGLPSIFHPETTDIYDKKNMPRAVYCLHALSLYLFKLGLAPQIQDLSGKVDFTEEEISDAGRELEKLGLQLPAFGRIGGILADELSLDEAAVHAAVLAINVAVERGDVGRTMEALLHPGAMLRGLRTALAAAYQDVLRGAQREKGGGREWVRTREGDIYTHCLTQAEIQENISRVNVHAALEEVDDAVQRGDALLLHRALQDPALSLPHLQRDNLQLCLEQLRAQRQQKELGYVELLDEEEHGSCSPDPIPAPSAVLRAVSAINAAIRRGIPAATLQALLEPSAQLPAAFPHAAALYQHQLALLQRQHPRVGLLQEELFVAVEMLSAVALVNRAVDAGNPEELWGGLLSPALGLSGVEEENAQRYFDALLQLKEQLRKEGAEFLSWTDIQDSVNATNASVQDETDRLLAVQRINAALRHADPQRTLAALLLPAAALPDVALPNAGRYHRVLSRARAAKAQVWGGGPWVALGTAAINQAIREGRAAQTLRVLRNPDVALRGVVDACAALYQEELQALAATKKPRGSTKPRWVRHRLRDGSEFYLSLQSFEGSWERPCDGELCATHLSREEIQSVITRVTAAHDRQRLWASNMAAVVGLQALLRGFLARRRFVALRRRHTAAVRIQASWRGYRQRKAYLQRLHYLRAHGDAVVKVGLLCLHPRLTPLCHRQGMRRIGAVVKIQAFVRANKARGDYRMLGDPPLGAVRRFIHVLEQNQSDFVEEAEVLRLREEVAKRIRASQQLEGDLSLMDIQIGLLVRNPRHEVVSQCRKLTRKNREQLSELMCLDKQKGLKSLSKEKRQKLEAYQHLFYLLQTQPTYLARLLFQVPQNKSTAFLQPVVFTLYSYASHPREGYLLLQLFKAALQEEIRCRVERIHDVLTGNAAVIRMVVGFYRSARGRSALRHILGRPVREVLRDATLSIRTDPVDIYKAWVNQAESQSGQRSGLPYEVSPEQALCHPEVRRRLDASVRALLAVTEKFVSAITSSVDQIPYGMRYVAKTLRASLAEKFPEASEEELDKVVGNLLYYRFMNPAVVAPDGFDVVDVSAGAALRPEQRRSLGSIAKVLQHAAARKAFEGENGHLCGANRYLEETHCKFRRFIAAACRVPEPKERFNVDEYSEMVAVAKPVIYITAGELIATHRLLLEHRDSIAPDPGDPLHELLEDLGELPTLQALVGTYGALPSQPSCSSRPPPPHPALPPIGEGAERALPPSVAPSTKQMLVDVIQCQPGGSLAEILRTPASELEEASHHHLMRRRALWDSQTPTKLNRHRSLVANSQLSVEEKKQRIVRNLRRLEVLGLVDAAQHYQGLINELAKDIRNQRRYRQHRREELLKLRQTLRALDAKTLFYEEQIDYYNQYIRSCLHGLAVLRGPFSFRANGKGKKLQPLRYTAARLLEMGVLLEIQDLPASQFRNVIFDIVPCREPGRFQVKAQFMGIDMERFQLHYQDLLQLQYEGVAVMKMFGKAKVNVNLLLFLLNKKFFKK", "length": 1593, "header": "tr|A0A8V1ACP2-1|A0A8V1ACP2_CHICK Computationally mapped isoform of IQ motif containing GTPase activating protein 3 OS=Gallus gallus OX=9031 GN=IQGAP3 PE=4 SV=1 CANONICAL=A0A8V1ACU5-1" }, "locus": { "chromosome": "25", "start_pos": 474899, "end_pos": 442743, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068239.1", "url": "https://www.ensembl.org/id/ENSGALT00010068239.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041982.1", "url": "https://www.ensembl.org/id/ENSGALP00010041982.1" } ] } }, { "isoform_ac": "A0A8V1ACU5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACU5/entry#A0A8V1ACU5-1", "sequence": { "sequence": "MYDVTGTQPGAAVLGFGAVRGTAARDPPGTAPAAVPAAGERPSAEQMDEQRRQNVAYQYLCRLEEAKRWMEACLGEELPPPTELEENLRNGVLLARLGHRFAPDAVPPARIYDPQQTRYRTSGLHFRHTDNINHWRCAMSRLGLPSIFHPETTDIYDKKNMPRAVYCLHALSLYLFKLGLAPQIQDLSGKVDFTEEEISDAGRELEKLGLQLPAFGRIGGILADELSLDEAAVHAAVLAINVAVERGDVGRTMEALLHPGAMLRGLRTALAAAYQDVLRGAQREKGGGREWVRTREGDIYTHCLTQAEIQENISRVNVHAALEEVDDAVQRGDALLLHRALQDPALSLPHLQRDNLQLCLEQLRAQRQQKALVGGLQWGAVQHGSCSPDPIPAPSAVLRAVSAINAAIRRGIPAATLQALLEPSAQLPAAFPHAAALYQHQLALLQRQHPRVGLLQEELFVAVEMLSAVALVNRAVDAGNPEELWGGLLSPALGLSGVEEENAQRYFDALLQLKEQLRKEGAEFLSWTDIQDSVNATNASVQDETDRLLAVQRINAALRHADPQRTLAALLLPAAALPDVALPNAGRYHRVLSRARAAKAQVWGGGPWVALGTAAINQAIREGRAAQTLRVLRNPDVALRGVVDACAALYQEELQALAATKKPRGSTKPRWVRHRLRDGSEFYLSLQSFEGSWERPCDGELCATHLSREEIQSVITRVTAAHDRQRLWASNMAAVVGLQALLRGFLARRRFVALRRRHTAAVRIQASWRGYRQRKAYLQRLHYLRAHGDAVVKVGLLCLHPRLTPLCHRQGMRRIGAVVKIQAFVRANKARGDYRMLGDPPLGAVRRFIHVLEQNQSDFVEEAEVLRLREEVAKRIRASQQLEGDLSLMDIQIGLLVRNPRHEVVSQCRKLTRKNREQLSELMCLDKQKGLKSLSKEKRQKLEAYQHLFYLLQTQPTYLARLLFQVPQNKSTAFLQPVVFTLYSYASHPREGYLLLQLFKAALQEEIRCRVERIHDVLTGNAAVIRMVVGFYRSARGRSALRHILGRPVREVLRDATLSIRTDPVDIYKAWVNQAESQSGQRSGLPYEVSPEQALCHPEVRRRLDASVRALLAVTEKFVSAITSSVDQIPYGMRYVAKTLRASLAEKFPEASEEELDKVVGNLLYYRFMNPAVVAPDGFDVVDVSAGAALRPEQRRSLGSIAKVLQHAAARKAFEGENGHLCGANRYLEETHCKFRRFIAAACRVPEPKERFNVDEYSEMVAVAKPVIYITAGELIATHRLLLEHRDSIAPDPGDPLHELLEDLGELPTLQALVGTYGALPSQPSSERALPPSVAPSTKQMLVDVIQCQPGGSLAEILRTPASELEEASHHHLMRRRALWDSQTPTKLNRHRSLVANSQLSVEEKKQRIVRNLRRLEVLGLVDAAQHYQGLINELAKDIRNQRRYRQHRREELLKLRQTLRALDAKTLFYEEQIDYYNQYIRSCLHGLAVLRGPFSFRANGKGKKLQPLRYTAARLLEMGVLLEIQDLPASQFRNVIFDIVPCREPGRFQVKAQFMGIDMERFQLHYQDLLQLQYEGVAVMKMFGKAKVNVNLLLFLLNKKFFKK", "length": 1605, "header": "tr|A0A8V1ACU5-1|A0A8V1ACU5_CHICK Isoform 1 of IQ motif containing GTPase activating protein 3 OS=Gallus gallus OX=9031 GN=IQGAP3 PE=4 SV=1 CANONICAL=A0A8V1ACU5-1" }, "locus": { "chromosome": "25", "start_pos": 474899, "end_pos": 442035, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068280.1", "url": "https://www.ensembl.org/id/ENSGALT00010068280.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042023.1", "url": "https://www.ensembl.org/id/ENSGALP00010042023.1" } ] } }, { "isoform_ac": "A0A8V1AHT3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACU5/entry#A0A8V1AHT3-1", "sequence": { "sequence": "HRYTSVPPPPPGDTGWMEACLGEELPPPTELEENLRNGVLLARLGHRFAPDAVPPARIYDPQQTRYRTSGLHFRHTDNINHWRCAMSRLGLPSIFHPETTDIYDKKNMPRAVYCLHALSLYLFKLGLAPQIQDLSGKVDFTEEEISDAGRELEKLGLQLPAFGRIGGILADELSLDEAAVHAAVLAINVAVERGDVGRTMEALLHPGAMLRGLRTALAAAYQDVLRGAQREKGGGREWVRTREGGMRVALGSLHAALEEVDDAVQRGDALLLHRALQDPALSLPHLQRDNLQLCLEQLRAQRQQKALVGARSSLQHGSCSPDPIPAPSAVLRAVSAINAAIRRGIPAATLQALLEPSAQLPAAFPHAAALYQHQLALLQRQHPRVGLLQEELFVAVEMLSAVALVNRAVDAGNPEELWGGLLSPALGLSGVEEENAQRYFDALLQLKEQLRKEGAEFLSWTDIQDSVNATNASVQDETDRLLAVQRINAALRHADPQRTLAALLLPAAALPDVALPNAGRYHRVLSRARAAKAQVWGGGPWVALGTAAINQAIREGRAAQTLRVLRNPDVALRGVVDACAALYQEELQALAATKKPRGSTKPRWVRHRLRDGSEFYLSLQSFEGSWERPCDGELCATHLSREEIQSVITRVTAAHDRQRLWASNMAAVVGLQALLRGFLARRRFVALRRRHTAAVRIQASWRGYRQRKAYLQRLHYLRAHGDAVVKIQAAVRMWRARKRYQERLRYFRRNVSDGGGAEPPLLCALRPARSPPLGAVRRFIHVLEQNQSDFVEEAEVLRLREEVAKRIRASQQLEGDLSLMDIQIGLLVRNPRHEVVSQCRKLTRKNREQLSELMCLDKQKGLKSLSKEKRQKLEAYQHLFYLLQTQPTYLARLLFQVPQNKSTAFLQPVVFTLYSYASHPREGYLLLQLFKAALQEEIRCRVERIHDVLTGNAAVIRMVVGFYRSARGRSALRHILGRPVREVLRDATLSIRTDPVDIYKAWVNQAESQSGQRSGLPYEVSPEQALCHPEVRRRLDASVRALLAVTEKFVSAITSSVDQIPYGMRYVAKTLRASLAEKFPEASEEELDKVVGNLLYYRFMNPAVVAPDGFDVVDVSAGAALRPEQRRSLGSIAKVLQHAAARKAFEGENGHLCGANRYLEETHCKFRRFIAAACRVPEPKERFNVDEYSEMVAVAKPVIYITAGELIATHRLLLEHRDSIAPDPGDPLHELLEDLGELPTLQALVGTYGALPSQPSSERALPPSVAPSTKQMLVDVIQCQPGGSLAEILRTPASELEEASHHHLMRRRALWDSQTPTKLNRHRSLVANSQLSVEEKKQRIVRNLRRLEVLGLVDAAQHYQGLINELAKDIRNQRRYRQHRREELLKLRQTLRALDAKTLFYEEQIDYYNQYIRSCLHGLAASNKANGKGKKLQPLRYTAARLLEMGVLLEIQDLPASQFRNVIFDIVPCREPGRFQVKAQFMGIDMERFQLHYQDLLQLQYEGVAVMKMFGKAKVNVNLLLFLLNKKFFKK", "length": 1531, "header": "tr|A0A8V1AHT3-1|A0A8V1ACU5_CHICK Computationally mapped isoform of IQ motif containing GTPase activating protein 3 OS=Gallus gallus OX=9031 GN=IQGAP3 PE=4 SV=1 CANONICAL=A0A8V1ACU5-1" }, "locus": { "chromosome": "25", "start_pos": 474899, "end_pos": 442718, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068250.1", "url": "https://www.ensembl.org/id/ENSGALT00010068250.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041993.1", "url": "https://www.ensembl.org/id/ENSGALP00010041993.1" } ] } }, { "isoform_ac": "A0A8V1AHV2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACU5/entry#A0A8V1AHV2-1", "sequence": { "sequence": "EVRRAAALGVPAAGERPSAEQMDEQRRQNVAYQYLCRLEEAKRWMEACLGEELPPPTELEENLRNGVLLARLGHRFAPDAVPPARIYDPQQTRYRTSGLHFRHTDNINHWRCAMSRLGLPSIFHPETTDIYDKKNMPRAVYCLHALSLYLFKLGLAPQIQDLSGKVDFTEEEISDAGRELEKLGLQLPAFGRIGGILADELSLDEAAVHAAVLAINVAVERGDVGRTMEALLHPGAMLRGLRTALAAAYQDVLRGAQREKGGGREWVRTREGGDIYTHCLTQAEIQENISRVNVHAALEEVDDAVQRGDALLLHRALQDPALSLPHLQRDNLQLCLEQLRAQRQQKALELGYVELLDEEEVAVGIQVANERGEEERAMLRAVSAINAAIRRGIPAATLQALLEPSAQLPAAFPHAAALYQHQLALLQRQHPRGELLQEELFVAVEMLSAVALVNRAVDAGNPEELWGGLLSPALGLSGVEEENAQRYFDALLQLKEQLRKEGAEFLSWTDIQDSVNATNASVQDETDRLLAVQRINAALRHADPQRTLAALLLPAAALPDVALPNAGRYHRVLSRARAAKAQVGDDGAELWWEEIERGVRAANEETAAVRRMALGTAAINQAIREGRAAQTLRVLRNPDVALRGVVDACAALYQEELQALAATKKPRGSTKPRWVRHRLRDGSEFYLSLQSFEGSWERPCDGELCATHLSREEIQSVITRVTAAHDRQRLWASNMAAVVGLQALLRGFLARRRFVALRRRHTAAVRIQASWRGYRQRKAYLQRLHYLRAHGDAVVKVGLLCLHPRLTPLCHRQGMRRVPSSVVKIQAFVRANKARGDYRMLVHERSPPLGAVRRFIHVLEQNQSDFVEEAEVLRLREEVAKRIRASQQLEGDLSLMDIQIGLLVRNPRHEVVSQCRKLTRKNREQLSELMCLDKQKGLKSLSKEKRQKLEAYQHLFYLLQTQPTYLARLLFQVPQNKSTAFLQPVVFTLYSYASHPREGYLLLQLFKAALQEEIRCRVERIHDVLTGNAAVIRMVVGFYRSARGRSALRHILGRPVREVLRDATLSIRTDPVDIYKAWVNQAESQSGQRSGLPYEVSPEQALCHPEVRRRLDASVRALLAVTEKFVSAITSSVDQIPYGMRYVAKTLRASLAEKFPEASEEELDKVVGNLLYYRFMNPAVVAPDGFDVVDVSAGAALRPEQRRSLGSIAKVLQHAAARKAFEGENGHLCGANRYLEETHCKFRWAPGGRAEGFQGPFALSSAPPPAPLCHSPLTRTAQLLLEHRDSIAPDPGDPLHELLEDLGELPTLQALVGTYGTLSREALGMYGGGAERALPPSVAPSTKQMLVDVIQCQPGGSLAEILRTPASELEEASHHHLMRRRALWDSQTPTKLNRHRSLVANSQLSVEEKKQRIVRNLRRLEVLGLVDAAQHYQGLINELAKDIRNQRRYRQHRREELLKLRQTLRALDAKTLFYEEQIDYYNQYIRSCLHGLAASNKANGKGKKLQPLRYTAARLLEMGVLLEIQDLPASQFRNVIFDIVPCREPGRFQVKAQFMGIDMERFQLHYQDLLQLQYEGVAVMKMFGKAKVNVNLLLFLLNKKFFKK", "length": 1604, "header": "tr|A0A8V1AHV2-1|A0A8V1ACU5_CHICK Computationally mapped isoform of IQ motif containing GTPase activating protein 3 OS=Gallus gallus OX=9031 GN=IQGAP3 PE=4 SV=1 CANONICAL=A0A8V1ACU5-1" }, "locus": { "chromosome": "25", "start_pos": 474899, "end_pos": 442358, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068276.1", "url": "https://www.ensembl.org/id/ENSGALT00010068276.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042019.1", "url": "https://www.ensembl.org/id/ENSGALP00010042019.1" } ] } }, { "isoform_ac": "A0A8V1AHW1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACU5/entry#A0A8V1AHW1-1", "sequence": { "sequence": "MYDVTGTQPGAAVLGFGAVRGTAARDPPGTAPAAVPAAGERPSAEQMDEQRRQNVAYQYLCRLEEAKRWMEACLGEELPPPTELEENLRNGVLLARLGHRFAPDAVPPARIYDPQQTRYRTSGLHFRHTDNINHWRCAMSRLGLPSIFHPETTDIYDKKNMPRAVYCLHALSLYLFKLGLAPQIQDLSGKVDFTEEEISDAGRELEKLGLQLPAFGRIGGILADELSLDEAAVHAAVLAINVAVERGDVGRTMEALLHPGAMLRGLRTALAAAYQDVLRGAQREKGGGREWVRTREGGMRVALVHAALEEVDDAVQRGDALLLHRALQDPALSLPHLQRDNLQLCLEQLRAQRQQKALVGARSSLQHGSCSPDPIPAPSAVLRAVSAINAAIRRGIPAATLQALLEPSAQLPAAFPHAAALYQHQLALLQRQHPRVGLLQEELFVAVEMLSAVALVNRAVDAGNPEELWGGLLSPALGLSGVEEENAQRYFDALLQLKEQLRKEGAEFLSWTDIQDSVNATNASVQDETDRLLAVQRINAALRHADPQRTLAALLLPAAALPDVALPNAGRYHRVLSRARAAKAQVWGGGPWVALGTAAINQAIREGRAAQTLRVLRNPDVALRGVVDACAALYQEELQALAATKKPRGTARGWDPPLTKPRWVRHRLRDGSEFYLSLQSFEGSWERPCDGELCATHLSREEIQSVITRVTAAHDRQRLWASNMAAVVGLQALLRGFLARRRFVALRRRHTAAVRIQASWRGYRQRKAYLQRLHYLRAHGDAVVKVGLLCLHPRLTPLCHRQGMRRIGAVVKIQAFVRANKARGDYRMLGDPPLGAVRRFIHVLEQNQSDFVEEAEVLRLREEVAKRIRASQQLEGDLSLMDIQIGLLVRNPRHEVVSQCRKLTRKNREQLSELMCLDKQKGLKSLSKEKRQKLEAYQHLFYLLQTQPTYLARLLFQVPQNKSTAFLQPVVFTLYSYASHPREGYLLLQLFKAALQEEIRCRVERIHDVLTGNAAVIRMVVGFYRSARGRSALRHILGRPVREVLRDATLSIRTDPVDIYKAWVNQAESQSGQRSGLPYEVSPEQALCHPEVRRRLDASVRALLAVTEKFVSAITSSVDQIPYGMRYVAKTLRASLAEKFPEASEEELDKVVGNLLYYRFMNPAVVAPDGFDVVDVSAGAALRPEQRRSLGSIAKVLQHAAARKAFEGENGHLCGANRYLEETHCKFRRFIAAACRVPEPKERFNVDEYSEMVAVAKPVIYITAGELIATHRLLLEHRDSIAPDPGDPLHELLEDLGELPTLQALVGTYGALPSQPSSERALPPSVAPSTKQMLVDVIQCQPGGSLAEILRTPASELEEASHHHLMRRRALWDSQTPTKLNRHRSLVANSQLSVEEKKQRIVRNLRRLEVLGLVDAAQHYQGLINELAKDIRNQRRYRQHRREELLKLRQTLRALDAKTLFYEEQIDYYNQYIRSCLHGLAVLRGPFSFRANGKGKKLQPLRYTAARLLEMGVLLEIQDLPASQFRNVIFDIVPCREPGRFQVKAQFMGIDMERFQLHYQDLLQLQYEGVAVMKMFGKAKVNVNLLLFLLNKKFFKK", "length": 1597, "header": "tr|A0A8V1AHW1-1|A0A8V1ACU5_CHICK Computationally mapped isoform of IQ motif containing GTPase activating protein 3 OS=Gallus gallus OX=9031 GN=IQGAP3 PE=4 SV=1 CANONICAL=A0A8V1ACU5-1" }, "locus": { "chromosome": "25", "start_pos": 474899, "end_pos": 442035, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068286.1", "url": "https://www.ensembl.org/id/ENSGALT00010068286.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042029.1", "url": "https://www.ensembl.org/id/ENSGALP00010042029.1" } ] } }, { "isoform_ac": "A0A8V1AJN1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACU5/entry#A0A8V1AJN1-1", "sequence": { "sequence": "EGETGGGGLYGERPSAEQMDEQRRQNVAYQYLCRLEEAKRWMEACLGEELPPPTELEENLRNGVLLARLGHRFAPDAVPPARIYDPQQTRYRTSGLHFRHTDNINHWRCAMSRLGLPSIFHPETTDIYDKKNMPRAVYCLHALSLYLFKLGLAPQIQDLSGKVDFTEEEISDAGRELEKLGLQLPAFGRIGGILADELSLDEAAVHAAVLAINVAVERGDVGRTMEALLHPGAMLRGLRTALAAAYQDVLRGAQREKGGGREWVRTREGDIYTHCLTQAEIQENISRVNVHAALEEVDDAVQRGDALLLHRALQDPALSLPHLQRDNLQLCLEQLRAQRQQKELGYVELLDEEEHGSCSPDPIPAPSAVLRAVSAINAAIRRGIPAATLQALLEPSAQLPAAFPHAAALYQHQLALLQRQHPRVGLLQEELFVAVEMLSAVALVNRAVDAGNPEELWGGLLSPALGLSGVEEENAQRYFDALLQLKEQLRKEGAEFLSWTDIQDSVNATNASVQDETDRLLAVQRINAALRHADPQRTLAALLLPAAALPDVALPNAGRYHRVLSRARAAKAQVWGGGPWVALGTAAINQAIREGRAAQTLRVLRNPDVALRGVVDACAALYQEELQALAATKKPRGSTKPRWVRHRLRDGSEFYLSLQSFEGSWERPCDGELCATHLSREEIQSVITRVTAAHDRQRLWASNMAAVVGLQALLRGFLARRRFVALRRRHTAAVRIQASWRGYRQRKAYLQRLHYLRAHGDAVVKVGLLCLHPRLTPLCHRQGMRRIGAVVKIQAFVRANKARGDYRMLGDPPLGAVRRFIHVLEQNQSDFVEEAEVLRLREEVAKRIRASQQLEGDLSLMDIQIGLLVRNPRHEVVSQCRKLTRKNREQLSELMCLDKQKGLKSLSKEKRQKLEAYQHLFYLLQTQPTYLARLLFQVPQNKSTAFLQPVVFTLYSYASHPREGYLLLQLFKAALQEEIRCRVERIHDVLTGNAAVIRMVVGFYRSARGRSALRHILGRPVREVLRDATLSIRTDPVDIYKAWVNQAESQSGQRSGLPYEVSPEQALCHPEVRRRLDASVRALLAVTEKFVSAITSSVDQIPYGMRYVAKTLRASLAEKFPEASEEELDKVVGNLLYYRFMNPAVVAPDGFDVVDVSAGAALRPEQRRSLGSIAKVLQHAAARKAFEGENGHLCGANRYLEETHCKFRRFIAAACRVPEPKERFNVDEYSEMVAVAKPVIYITAGELIATHRLLLEHRDSIAPDPGDPLHELLEDLGELPTLQALVGTYGALPSQPSCSSRPPPPHPALPPIGEGAERALPPSVAPSTKQMLVDVIQCQPGGSLAEILRTPASELEEASHHHLMRRRALWDSQTPTKLNRHRSLVANSQLSVEEKKQRIVRNLRRLEVLGLVDAAQHYQGLINELAKDIRNQRRYRQHRREELLKLRQTLRALDAKTLFYEEQIDYYNQYIRSCLHGLAVLRGPFSFRANGKGKKLQPLRYTAARLLEMGVLLEIQDLPASQFRNVIFDIVPCREPGRFQVKAQFMGIDMERFQLHYQDLLQLQYEGVAVMKMFGKAKVNVNLLLFLLNKKFFKK", "length": 1595, "header": "tr|A0A8V1AJN1-1|A0A8V1ACU5_CHICK Computationally mapped isoform of IQ motif containing GTPase activating protein 3 OS=Gallus gallus OX=9031 GN=IQGAP3 PE=4 SV=1 CANONICAL=A0A8V1ACU5-1" }, "locus": { "chromosome": "25", "start_pos": 474899, "end_pos": 442686, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068253.1", "url": "https://www.ensembl.org/id/ENSGALT00010068253.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041996.1", "url": "https://www.ensembl.org/id/ENSGALP00010041996.1" } ] } }, { "isoform_ac": "A0A8V1AJQ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACU5/entry#A0A8V1AJQ3-1", "sequence": { "sequence": "MDEQRRQNVAYQYLCRLEEAKRWMEACLGEELPPPTELEENLRNGVLLARLGHRFAPDAVPPARIYDPQQTRYRTSGLHFRHTDNINHWRCAMSRLGLPSIFHPETTDIYDKKNMPRAVYCLHALSLYLFKLGLAPQIQDLSGKVDFTEEEISDAGRELEKLGLQLPAFGRIGGILADELSLDEAAVHAAVLAINVAVERGDVGRTMEALLHPGAMLRGLRTALAAAYQDVLRGAQREKGGGREWVRTREGGMRVALGSCRAGRRGHLHPLPDAVHAALEEVDDAVQRGDALLLHRALQDPALSLPHLQRDNLQLCLEQLRAQRQQKALVGARSSRAHAGGVQGGVLRAVSAINAAIRRGIPAATLQALLEPSAQLPAAFPHAAALYQHQLALLQRQHPRGELLQEELFVAVEMLSAVALVNRAVDAGNPEELWGGLLSPALGLSGVEEENAQRYFDALLQLKEQLRKEGAEFLSWTDIQDSVNATNASVQDETDRLLAVQRINAALRHADPQRTLAALLLPAAALPDVALPNAGRYHRVLSRARAAKAQVGDDGAELWWEEIERGVRAANEETAAVRLALGTAAINQAIREGRAAQTLRVLRNPDVALRGVVDACAALYQEELQALAATKKPRGSTKPRWVRHRLRDGSEFYLSLQSFEGSWERPCDGELCATHLSREEIQSVITRVTAAHDRQRLWASNMAAVVGLQALLRGFLARRRFVALRRRHTAAVRIQASWRGYRQRKAYLQRLHYLRAHGDAVVKVGLLCLHPRLTPLCHRQGMRRVPSSVVKIQAFVRANKARGDYRMLVHERSPPLGAVRRFIHVLEQNQSDFVEEAEVLRLREEVAKRIRASQQLEGDLSLMDIQIGLLVRNPRHEVVSQCRKLTRKNREQLSELMCLDKQKGLKSLSKEKRQKLEAYQHLFYLLQTQPTYLARLLFQVPQNKSTAFLQPVVFTLYSYASHPREGYLLLQLFKAALQEEIRCRVERIHDVLTGNAAVIRMVVGFYRSARGRSALRHILGRPVREVLRDATLSIRTDPVDIYKAWVNQAESQSGQRSGLPYEVSPEQALCHPEVRRRLDASVRALLAVTEKFVSAITSSVDQIPYGMRYVAKTLRASLAEKFPEASEEELDKVVGNLLYYRFMNPAVVAPDGFDVVDVSAGAALRPEQRRSLGSIAKVLQHAAARKAFEGENGHLCGANRYLEETHCKFRWAFIAAACRVPEPKERFNVDEYSEMVAVAKPVIYITAGELIATHRLLLEHRDSIAPDPGDPLHELLEDLGELPTLQALVGTYGTLSREALGMYGGGAERALPPSVAPSTKQMLVDVIQCQPGGSLAEILRTPASELEEASHHHLMRRRALWDSQTPTKLNRHRSLVANSQLSVEEKKQRIVRNLRRLEVLGLVDAAQHYQGLINELAKDIRNQRRYRQHRREELLKLRQTLRALDAKTLFYEEQIDYYNQYIRSCLHGLAASNKANGKGKKLQPLRYTAARLLEMGVLLEIQDLPASQFRNVIFDIVPCREPGRFQVKAQFMGIDMERFQLHYQDLLQLQYEGVAVMKMFGKAKVNVNLLLFLLNKKFFKK", "length": 1581, "header": "tr|A0A8V1AJQ3-1|A0A8V1ACU5_CHICK Computationally mapped isoform of IQ motif containing GTPase activating protein 3 OS=Gallus gallus OX=9031 GN=IQGAP3 PE=4 SV=1 CANONICAL=A0A8V1ACU5-1" }, "locus": { "chromosome": "25", "start_pos": 474899, "end_pos": 442829, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068279.1", "url": "https://www.ensembl.org/id/ENSGALT00010068279.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042022.1", "url": "https://www.ensembl.org/id/ENSGALP00010042022.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-5626467", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5626467", "resource": "Reactome", "description": "RHO GTPases activate IQGAPs" }, { "id": "R-GGA-8980692", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8980692", "resource": "Reactome", "description": "RHOA GTPase cycle" }, { "id": "R-GGA-9013026", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013026", "resource": "Reactome", "description": "RHOB GTPase cycle" }, { "id": "R-GGA-9013106", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013106", "resource": "Reactome", "description": "RHOC GTPase cycle" }, { "id": "R-GGA-9013149", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013149", "resource": "Reactome", "description": "RAC1 GTPase cycle" }, { "id": "R-GGA-9013406", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013406", "resource": "Reactome", "description": "RHOQ GTPase cycle" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "calmodulin binding", "id": "GO:0005516", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005516", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACU5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACU5" } ], "pmid": "" }, { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACU5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACU5" } ], "pmid": "" }, { "name": "actin filament binding", "id": "GO:0051015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051015", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACU5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACU5" } ], "pmid": "" }, { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACU5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACU5" } ], "pmid": "" }, { "name": "myosin VI light chain binding", "id": "GO:0070856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070856", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACU5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACU5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "plasma membrane bounded cell projection", "id": "GO:0120025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120025", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACU5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACU5" } ], "pmid": "" }, { "name": "cell-cell junction", "id": "GO:0005911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005911", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACU5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACU5" } ], "pmid": "" }, { "name": "cell cortex", "id": "GO:0005938", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005938", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACU5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACU5" } ], "pmid": "" }, { "name": "lateral plasma membrane", "id": "GO:0016328", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016328", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACU5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACU5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "mitotic actomyosin contractile ring assembly actin filament organization", "id": "GO:1903479", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903479", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACU5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACU5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 312, "end_pos": 314, "annotation": "n_glycosylation_sequon" }, { "start_pos": 535, "end_pos": 537, "annotation": "n_glycosylation_sequon" }, { "start_pos": 538, "end_pos": 540, "annotation": "n_glycosylation_sequon" }, { "start_pos": 855, "end_pos": 857, "annotation": "n_glycosylation_sequon" }, { "start_pos": 969, "end_pos": 971, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1ACU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACU5" }, { "id": "PS50021", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50021" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Calponin-homology (CH)", "eco_id": "ECO_0000259", "start_pos": 60, "end_pos": 175, "start_aa": "Leu", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1ACU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACU5" }, { "id": "PS50018", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50018" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ras-GAP", "eco_id": "ECO_0000259", "start_pos": 977, "end_pos": 1210, "start_aa": "Pro", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 312, "end_pos": 314 }, { "start_pos": 535, "end_pos": 537 }, { "start_pos": 538, "end_pos": 540 }, { "start_pos": 855, "end_pos": 857 }, { "start_pos": 969, "end_pos": 971 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1ACV9-1", "uniprot_ac": "A0A8V1ACV9", "uniprot_id": "A0A8V1ACV9_CHICK", "mass": { "chemical_mass": 245186.0, "monoisotopic_mass": 245186.0 }, "refseq": { "ac": "XP_004934392", "name": "calcineurin-binding protein cabin-1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004934392" }, "gene_names": [ { "name": "CABIN1", "type": "recommended", "evidence": [ { "id": "A0A8V1ACV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACV9" } ] }, { "name": "CABIN1", "type": "synonym", "evidence": [ { "id": "XP_004934392", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004934392" } ] } ], "protein_names": [ { "name": "Calcineurin-binding protein cabin-1", "type": "recommended", "evidence": [ { "id": "A0A8V1ACV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACV9/entry#names_and_taxonomy" } ] }, { "name": "Calcineurin inhibitor", "type": "synonym", "evidence": [ { "id": "A0A8V1ACV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACV9/entry#names_and_taxonomy" } ] }, { "name": "calcineurin-binding protein cabin-1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_004934392", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004934392" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052546.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004934392.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004934392", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004934392" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACV9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACV9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CABIN1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACV9", "locus": { "chromosome": "15", "start_pos": 8224993, "end_pos": 8130756, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010026167", "url": "https://www.ensembl.org/id/ENSGALG00010026167" } ] } } ], "crossref": [ { "id": "cd13839", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13839", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "416938", "url": "https://www.ncbi.nlm.nih.gov/gene/416938", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015134", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015134", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019734", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019734", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033053", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033053", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416938", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416938", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HAKANIP", "url": "https://omabrowser.org/oma/group/HAKANIP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A7W9", "url": "https://www.orthodb.org/?gene=A0A8V1A7W9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AAL9", "url": "https://www.orthodb.org/?gene=A0A8V1AAL9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ACV9", "url": "https://www.orthodb.org/?gene=A0A8V1ACV9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15502", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15502", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15502:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15502:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF09047", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09047", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-2559584", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2559584", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_004934392", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004934392", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1A7W9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7W9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A7W9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7W9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AAL9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAL9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AAL9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAL9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ACV9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACV9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ACV9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACV9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNMIRIAALNASSTIEDDYEGTFKSHKTQTKEAQEAEAFALYHKALDLQKHDRFEESAKAYHELLEIRLLREAVLSGDEKEGLKHPGLMLKYSTYKNLAQLAVQRDDLETAMEFYLEAVMLDSTDVNLWYKIGRVAIKLIRLPLARHAFEEGLRCNPDHWPCLDNLITILYTLSDYPTCLYFICKALEKDCLYSKGLVLKEKIFEEQPLLRKDSLRMFLKCDMSIHNVNVSTAETGRIIDEALELRKKRQALLVQEREPDLKLIQPIPFFTWKCLGEALLAMYHHLTTCDPPRPSLGKRIDLSEYRDPVQHLVLSPTSTPVSVIQPTPVSTAAVVTMPEPVLAYTPVTPNFPSHSQNSLEPGSTVGEQGDISAGDKSKKGVKRRRITEDSGETAKRRSARVRNTKCKKEEKVDFQELLVKFLPSRLRKLDPEEEEDPFNNYEVQSEIKEENFQHVGPHRMSFDSTTFMESEKQDVHEFLLDNLNNGGILELMMRYLKVISQKFLVKWPPGLSEVVLSIYTSWRKHSTSLPNPLLRDSSNQHIKDMMLMSLSCMELQLDQWLLAKGKNSTVSPRNCPAVSVNGKFGSDLPGIHFLGDLLQLSFASSQRDLFEEGWMEFVTRVYWLKARFLALQGDMEQALENYDICTEMLQSSTTMQRKAGDDSNIVIRLPNLHVDSVVSLEEIDKNLKSLERCQSLEEIQRLYEAGDYTAVVHLLRPTLCFSGRVKHLEFVTSIPERPAQLLLLQDSLLKLKDYRQCFECSEVALNEASQQMMNMTAASAKEEWVATVTQLLIGIDSSLSSDNSILKESSITSSLVRLTTNLIQIIDCSMAVQEEPKEPYVSSVLPWIILHRIIQHEEDAFRSLCCQQQQNQGEGVNPDTPMLPSSLMLLNTAHEYLGRRSWCCNSDGALLKFYVQVLEKELAASTSEDTHPYKEELETALEQCFYCLYGFPSKKSKARYLEEHSVQQVDLTWEDALFMFEYFKPKTLPEFDSYKTSTVSADLANLLKKTATIVPRTDKPMLSLDTVSAYIEGTCSKAPSLPDGADYSPPVVTELYYLLADYHFKNKEQSKAIKFYMHDICICPNRFDSWAGMALARASRIQDKLNSNELKSDGPIWKHSTPVLNCFKRALEIDSSNLSLWIEYGTISYALHSFASRQLKQWKSELPPEVVQQMEERRDSMLETAKLCFTSASRCEGDGDEEEWLIHYMLGKIAEKQKQPPVVYLLHYKQAGHYLHEEAARYPKKIHYHNPPELAMEALEVYFRLHASILKLVGKPDSGVDAEILVSFMKEASEGPFARGEEKNTPKAAEKEKACMVDEDSHSSAGTVPGPGTSLPSSSGPGLTSPPYTATPVDHDYVKCKKPCQQATPDERSQDSTAAVLSDSSSTQDMFNEPASSQDSLRKPYTEKRISTACTDALMPSKEILGSTEEKITGKSEELLESSESYHVEPAGQKVLVDPQPASGNPSKASIPPPSQWDWKKKAETCGDGSEFPQGLPADLEEQRKFLTEQCVASFCLCLSRFPQHYKSLYRLAYLYTYSKTHKNLQWARDVLLGSGVPWQQLKHMPAQGLFCERNKTNFFNGIWRIPVDEIDRPGSFASHMNRSIVLLLNVLSQLKDYNTLLKVSSMLQRTPDQGKKYLRDADRQVLAQQAFVLTVKVLEDTLNDLTQVSEDQSSKSSNLASGRMTTDVSNKSSAEEGKDVLPKKTVLSDGVVHSTENGVKEVTQGQIPNAMDILEHEDKNAKEIRELPRPGSVEPMDFDGYSNDPEKMDSLCKRSEPDRLQSGRNSKERAPESRTAELSLEELSISSKQQQQGTKVQAVPTEEPVQRSSRKRKLLEDVESGKTLLLDAYRVWQQGQKVMAYDLGKIEKIMSETYMLIKQVDEEVALEQAVKFCQVHMGASAQKQSTAETPTTPKHTKDNRESFFPVTPATLHPAPVNPDTVTPENLLRLNDLHSKSKPASSSSSSSSSASSSVPPSQESHRDTEHLRSQNAETAPSMSDAREEEELEVPLEGLGFQQQESRLCQQMKMATVAPSPEPVCWQVESVTSTDSGHVCTQASSSKPELSSSSQTLGSQQNKTDGTRVKTRILPNMPKLFIPSSVTKFPPEITVTPPTPTLLSPKGSISEETKQKLKSAILSAQSAANVKKESLCQPALEILETSSQESSLESDTDEDDDYMDI", "length": 2180, "header": "tr|A0A8V1ACV9-1|A0A8V1ACV9_CHICK Isoform 1 of Calcineurin-binding protein cabin-1 OS=Gallus gallus OX=9031 GN=CABIN1 PE=4 SV=1 CANONICAL=A0A8V1ACV9-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A7W9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACV9/entry#A0A8V1A7W9-1", "sequence": { "sequence": "MNMIRIAALNASSTIEDDYEGTFKSHKTQTKEAQEAEAFALYHKALDLQKHDRFEESAKAYHELLEIRLLREAVLSGDEKEGLKHPGLMLKYSTYKNLAQLAVQRDDLETAMEFYLEAVMLDSTDVNLWYKIGRVAIKLIRLPLARHAFEEGLRCNPDHWPCLDNLITILYTLSDYPTCLYFICKALEKDCLYSKGLVLKEKIFEEQPLLRKDSLRMFLKCDMSIHNVNVSTAETGRIIDEALELRKKRQALLVQEREPDLKLIQPIPFFTWKCLGEALLAMYHHLTTCDPPRPSLGKRIDLSEYRDPVQHLVLSPTSTPVSVIQPTPVSTAAVVTMPEPVLAYTPVTPNFPSHSQNSLEPGSTVGEQGDISAGDKSKKGVKRRRITEDSGETAKRRSARVRNTKCKKEEKVDFQELLVKFLPSRLRKLDPEEEEDPFNNYEVQSEIKEENFQHVGPHRMSFDSTTFMESEKQDVHEFLLDNLNNGGILELMMRYLKVISQKFLVKWPPGLSEVVLSIYTSWRKHSTSLPNPLLRDSSNQHIKDMMLMSLSCMELQLDQWLLAKGKNSTVSPRNCPAVSVNGKFGSDLPGIHFLGDLLQLSFASSQRDLFEEGWMEFVTRVYWLKARFLALQGDMEQALENYDICTEMLQSSTTMQRKAGDDSNIVIRLPNLHVDSVVSLEEIDKNLKSLERCQSLEEIQRLYEAGDYTAVVHLLRPTLCFSGRVKHLEFVTSIPERPAQLLLLQDSLLKLKDYRQCFECSEVALNEASQQMMNMTAASAKEEWVATVTQLLIGIDSSLSSDNSILKESSITSSLVRLTTNLIQIIDCSMAVQEEPKEPYVSSVLPWIILHRIIQHEEDAFRSLCCQQQQNQGEGVNPDTPMLPSSLMLLNTAHEYLGRRSWCCNSDGALLKFYVQVLEKELAASTSEDTHPYKEELETALEQCFYCLYGFPSKKSKARYLEEHSVQQVDLTWEDALFMFEYFKPKTLPEFDSYKTSTVSADLANLLKKTATIVPRTDKPMLSLDTVSAYIEGTCSKAPSLPDGADYSPPVVTELYYLLADYHFKNKEQSKAIKFYMHDICICPNRFDSWAGMALARASRIQDKLNSNELKSDGPIWKHSTPVLNCFKRALEIDSSNLSLWIEYGTISYALHSFASRQLKQWKSELPPEVVQQMEERRDSMLETAKLCFTSASRCEGDGDEEEWLIHYMLGKIAEKQKQPPVVYLLHYKQAGHYLHEEAARYPKKIHYHNPPELAMEALEVYFRLHASILKLVGKPDSGVDAEILVSFMKEASEGPFARGEEKNTPKAAEKEKACMVDEDSHSSAGTVPGPGTSLPSSSGPGLTSPPYTATPVDHDYVKCKKPCQQATPDERSQDSTAAVLSDSSSTQDMFNEPASSQDSLRKPYTEKRISTACTDALMPSKEILGSTEEKITGKSEELLESSESYHVEPAGQKVLVDPQPASGNPSKASIPPPSQWDWKKKAETCGDGSEFPQGLPADLEEQRKFLTEQCVASFCLCLSRFPQHYKSLYRLAYLYTYSKTHKNLQWARDVLLGSGVPWQQLKHMPAQGLFCERNKTNFFNGIWRIPVDEIDRPGSFASHMNRSIVLLLNVLSQLKDYNTLLKVSSMLQRTPDQGKKYLRDADRQVLAQQAFVLTVKVLEDTLNDLTQVSEDQSSKSSNLASGRMTTDVSNKSSAEEGKDVLPKKTVLSDGVVHSTENGVKEVTQGQIPNAMDILEHEDKNAKEIRELPRPGSVEPMDFDGYSNDPEKMDSLCKRSEPDRLQSGRNSKERAPESRTAELSLEELSISSKQQQQGTKVQAVPTEEPVQRSSRKRKLLEDVESGKTLLLDAYRVWQQGQKVMAYDLGKIEKIMSETYMLIKQVDEEVALEQAVKFCQVHMGASAQKQSTAETPTTPKHTKDNRESFFPVTPATLHPAPVNPDTVTPENLLRLNDLHSKSKPASSSSSSSSSASSSVPPSQESHRDTEHLRSQNAETAPSMSDARASSSKPELSSSSQTLGSQQNKTDGTRVKTRILPNMPKLFIPSSVTKFPPEITVTPPTPTLLSPKGSISEETKQKLKSAILSAQSAANVKKESLCQPALEILETSSQESSLESDTDEDDDYMDI", "length": 2125, "header": "tr|A0A8V1A7W9-1|A0A8V1ACV9_CHICK Computationally mapped isoform of Calcineurin-binding protein cabin-1 OS=Gallus gallus OX=9031 GN=CABIN1 PE=4 SV=1 CANONICAL=A0A8V1ACV9-1" }, "locus": { "chromosome": "15", "start_pos": 8223749, "end_pos": 8132317, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063736.1", "url": "https://www.ensembl.org/id/ENSGALT00010063736.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039324.1", "url": "https://www.ensembl.org/id/ENSGALP00010039324.1" } ] } }, { "isoform_ac": "A0A8V1AAL9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACV9/entry#A0A8V1AAL9-1", "sequence": { "sequence": "MGIWRIPVDEIDRPGSFASHMNRSIVLLLNVLSQLKDYNTLLKVSSMLQRTPDQGKKYLRDADRQVLAQQAFVLTVKVLEDTLNDLTQVSEDQSSKSSNLASGRMTTDVSNKSSAEEGKDVLPKKTVLSDGVVHSTENGVKEVTQGQIPNAMDILEHEDKNAKEIRELPRPGSVEPMDFDGYSNDPEKMDSLCKRSEPDRLQSGRNSKERAPESRTAELSLEELSISSKQQQQGTKVQAVPTEEPVQRSSRKRKLLEDVESGKTLLLDAYRVWQQGQKVMAYDLGKIEKIMSETYMLIKQVDEEVALEQAVKFCQVHMGASAQKQSTAETPTTPKHTKDNRESFFPVTPATLHPAPVNPDTVTPENLLRLNDLHSKSKPASSSSSSSSSASSSVPPSQESHRDTEHLRSQNAETAPSMSDARASSSKPELSSSSQTLGSQQNKTDGTRVKTRILPNMPKLFIPSSVTKFPPEITVTPPTPTLLSPKGSISEETKQKLKSAILSAQSAANVKKESLCQPALEILETSSQESSLESDTDEDDDYMDI", "length": 545, "header": "tr|A0A8V1AAL9-1|A0A8V1ACV9_CHICK Computationally mapped isoform of Calcineurin-binding protein cabin-1 OS=Gallus gallus OX=9031 GN=CABIN1 PE=4 SV=1 CANONICAL=A0A8V1ACV9-1" }, "locus": { "chromosome": "15", "start_pos": 8223749, "end_pos": 8183257, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063723.1", "url": "https://www.ensembl.org/id/ENSGALT00010063723.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039318.1", "url": "https://www.ensembl.org/id/ENSGALP00010039318.1" } ] } }, { "isoform_ac": "A0A8V1ACV9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACV9/entry#A0A8V1ACV9-1", "sequence": { "sequence": "MNMIRIAALNASSTIEDDYEGTFKSHKTQTKEAQEAEAFALYHKALDLQKHDRFEESAKAYHELLEIRLLREAVLSGDEKEGLKHPGLMLKYSTYKNLAQLAVQRDDLETAMEFYLEAVMLDSTDVNLWYKIGRVAIKLIRLPLARHAFEEGLRCNPDHWPCLDNLITILYTLSDYPTCLYFICKALEKDCLYSKGLVLKEKIFEEQPLLRKDSLRMFLKCDMSIHNVNVSTAETGRIIDEALELRKKRQALLVQEREPDLKLIQPIPFFTWKCLGEALLAMYHHLTTCDPPRPSLGKRIDLSEYRDPVQHLVLSPTSTPVSVIQPTPVSTAAVVTMPEPVLAYTPVTPNFPSHSQNSLEPGSTVGEQGDISAGDKSKKGVKRRRITEDSGETAKRRSARVRNTKCKKEEKVDFQELLVKFLPSRLRKLDPEEEEDPFNNYEVQSEIKEENFQHVGPHRMSFDSTTFMESEKQDVHEFLLDNLNNGGILELMMRYLKVISQKFLVKWPPGLSEVVLSIYTSWRKHSTSLPNPLLRDSSNQHIKDMMLMSLSCMELQLDQWLLAKGKNSTVSPRNCPAVSVNGKFGSDLPGIHFLGDLLQLSFASSQRDLFEEGWMEFVTRVYWLKARFLALQGDMEQALENYDICTEMLQSSTTMQRKAGDDSNIVIRLPNLHVDSVVSLEEIDKNLKSLERCQSLEEIQRLYEAGDYTAVVHLLRPTLCFSGRVKHLEFVTSIPERPAQLLLLQDSLLKLKDYRQCFECSEVALNEASQQMMNMTAASAKEEWVATVTQLLIGIDSSLSSDNSILKESSITSSLVRLTTNLIQIIDCSMAVQEEPKEPYVSSVLPWIILHRIIQHEEDAFRSLCCQQQQNQGEGVNPDTPMLPSSLMLLNTAHEYLGRRSWCCNSDGALLKFYVQVLEKELAASTSEDTHPYKEELETALEQCFYCLYGFPSKKSKARYLEEHSVQQVDLTWEDALFMFEYFKPKTLPEFDSYKTSTVSADLANLLKKTATIVPRTDKPMLSLDTVSAYIEGTCSKAPSLPDGADYSPPVVTELYYLLADYHFKNKEQSKAIKFYMHDICICPNRFDSWAGMALARASRIQDKLNSNELKSDGPIWKHSTPVLNCFKRALEIDSSNLSLWIEYGTISYALHSFASRQLKQWKSELPPEVVQQMEERRDSMLETAKLCFTSASRCEGDGDEEEWLIHYMLGKIAEKQKQPPVVYLLHYKQAGHYLHEEAARYPKKIHYHNPPELAMEALEVYFRLHASILKLVGKPDSGVDAEILVSFMKEASEGPFARGEEKNTPKAAEKEKACMVDEDSHSSAGTVPGPGTSLPSSSGPGLTSPPYTATPVDHDYVKCKKPCQQATPDERSQDSTAAVLSDSSSTQDMFNEPASSQDSLRKPYTEKRISTACTDALMPSKEILGSTEEKITGKSEELLESSESYHVEPAGQKVLVDPQPASGNPSKASIPPPSQWDWKKKAETCGDGSEFPQGLPADLEEQRKFLTEQCVASFCLCLSRFPQHYKSLYRLAYLYTYSKTHKNLQWARDVLLGSGVPWQQLKHMPAQGLFCERNKTNFFNGIWRIPVDEIDRPGSFASHMNRSIVLLLNVLSQLKDYNTLLKVSSMLQRTPDQGKKYLRDADRQVLAQQAFVLTVKVLEDTLNDLTQVSEDQSSKSSNLASGRMTTDVSNKSSAEEGKDVLPKKTVLSDGVVHSTENGVKEVTQGQIPNAMDILEHEDKNAKEIRELPRPGSVEPMDFDGYSNDPEKMDSLCKRSEPDRLQSGRNSKERAPESRTAELSLEELSISSKQQQQGTKVQAVPTEEPVQRSSRKRKLLEDVESGKTLLLDAYRVWQQGQKVMAYDLGKIEKIMSETYMLIKQVDEEVALEQAVKFCQVHMGASAQKQSTAETPTTPKHTKDNRESFFPVTPATLHPAPVNPDTVTPENLLRLNDLHSKSKPASSSSSSSSSASSSVPPSQESHRDTEHLRSQNAETAPSMSDAREEEELEVPLEGLGFQQQESRLCQQMKMATVAPSPEPVCWQVESVTSTDSGHVCTQASSSKPELSSSSQTLGSQQNKTDGTRVKTRILPNMPKLFIPSSVTKFPPEITVTPPTPTLLSPKGSISEETKQKLKSAILSAQSAANVKKESLCQPALEILETSSQESSLESDTDEDDDYMDI", "length": 2180, "header": "tr|A0A8V1ACV9-1|A0A8V1ACV9_CHICK Isoform 1 of Calcineurin-binding protein cabin-1 OS=Gallus gallus OX=9031 GN=CABIN1 PE=4 SV=1 CANONICAL=A0A8V1ACV9-1" }, "locus": { "chromosome": "15", "start_pos": 8223749, "end_pos": 8132317, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063730.1", "url": "https://www.ensembl.org/id/ENSGALT00010063730.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039321.1", "url": "https://www.ensembl.org/id/ENSGALP00010039321.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1928, "start_aa": "Thr", "end_pos": 1928, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1928", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 327, "start_aa": "Thr", "end_pos": 327, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr327", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:416938", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416938", "resource": "KEGG Pathway" }, { "id": "R-GGA-2559584", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2559584", "resource": "Reactome", "description": "Formation of Senescence-Associated Heterochromatin Foci (SAHF)" } ], "orthologs": [ { "uniprot_canonical_ac": "G3HY02-1", "protein_name": "Calcineurin-binding protein cabin-1", "gene_name": "Cabin1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MIRIAALNASSTVEDDHEGSFRGHKAQTKEAQEAEAFALYHKALDLQKHDRFEESAKAYHELLEARLLREAVSSGDEKEGLKHPGLILKYSTYKNLAQLAAQREDLETAMEFYLEAVMLDSTDVNLWYKIGHVALRLIRLPLARHAFEEGLRCNPDHWPCLDNLITVLYTLSDYTTCLYFICKALEKDCQYSKGLVLKEKIFEEQPCLRKDSLRMFLKCDMSIHDVSVSAAETQAIVEEALGLRKKRQALIVREKEPDLKLVQPIPFFTWKCLGESLLAMYNHLTTCEPPRPSLGKRIDLSDYQDPNQLLASSAVVTPVSVVQPSPVSTNPTVAVAEPVLSYTSVTTASFPLHSPGLLDTSAPMGDASGGDKSKKGVKRKKTLEESGETAKRRSARVRNTKCKKEEKVDFQGLLVKFLPSRLRKLDPEEEDDPFNNYEVQSEAKLESFSNAGPHRLSFDSATFMESEKQDVHEFLMENLTNGGILELMMRYLKSMGHKFLLKWPPGLADVVLSVYHSWRRHSTSLPNPLLRDCSNEHIKDMMLMSLSCMELQLDQWLLTKGRSSTVSPRNCPAGVVTGRFGPDFPGTHCLGDLLQLSFASSQRDLFEDGWLEFVVRVYWLKARFLALQGDMEQALENYDICTEMLQNSSAIQAEAGAEQGDVVIRLPNLQNDSVVSLEEIDKNLKSLERCQSLEEIQRLFEAGDYKAVVRLLRPTLCTSGFDRAKHLEFMTSIPERPAQLLLLQDSLLRLKDHKQCFECSDVALNEAVQQMVNSSESAAKEEWVATVTQLLLGIEQALSSDSSGSILKESSSTTGLVRLTNNLIQVIDCSMAVQEEPKEPYVSSVLPWIILHRIIWQEEDTFRSLCHQQQLQNPAEEGMSEMPLLPSSLMLLNTAHEYLGRRSWCCNSDGALLRFYVQVLQKELAASASEDTHPYKEELETALEQCFYCLYSFPSKKSKARYLEEHSAQQVDLIWEDALFMFEYFKPKTLPEFDSYKTSTVSADLANLLKRIATIVPRTEKPALSMDKVSAYIEGTSAEVPCLPDGADPTPPVVSELYYLLADYHFKNKEQSKAIKFYMHDICICPNRFDSWAGMALARASRIQDKLNSNELKSDGPIWKHATPVLNCFRRALEIDSSNLSLWIEYGTMSYALHSFASRQLKQWRAELPPELIQQMEDRRDSMLETARHCFTSAAHCEGDGDEEEWLIHYMLGKVAEKQQQPPTVYLLHYRQAGHYLHEEAARYPKKIHYHNPPELAMEALEVYFRLHASILKLLGKPDSGVAAEVLVSFMKEAAEGPFARGEEKNTPKASEKEKACLVDEDSHSSAGTLPGPGASLPSSSGPGLTSPPYTATPIDHDYVKCKKPHQQATPDDRSQDSTAVALSDSSSTQDFFNEPTSLLEGSRKPLAEKRLSGLSAQAGPTGKDLPGPTEERGKTEESLESAEAFRVVEQGIQKPVADSSTSAYIPSKPLVSTPPLWDGKKRGDPLGEPVAFPQGLPADAEEQRQFLTEQCISSFCLCLSRFPQHYKSLYRLAFLYTYSKTHRNLQWARDVLLGSSIPWQQLQHMPAQGLFCERNKTNFFNGIWRIPVDEIDRPGSFAWHMNRSIVLLLKVLAQLRDHSTLLKVSSMLQRTPDQGKKYLRDADRQVLAQRAFILTVKVLEDTLSELAGGLEHPGPKPCGLSGARMTTDVSHKASPEDGQESLPHPKKLPLADGSGPGPEPGGKVGPLNQLPMATDTRDSTDQGGERKDKENPQAGPTELMDTSEVAVRHPDSEQTSPLLPGRPPRDRPPESRSAELSLEELSISSRQQPTPLTPSPVTLTTTTPPTMGARGGGHPEEAPPRPNRKRKLLEDTESGKTLLLDAYRVWQQGQKGMAYDLGRIEKIMSETYMLIKQVDEETALEQAVKFCQVHLGAAAQRQASGDAPTTPKHPKDSRENFFPATVAPTAPDPLPADALQRPSDSHVKPQTVLASATAVISCPPSSSTSTTDLSTDPGIPRPHRPEATTSMTSLSPEGEEQSGATEGTSFPPQEPRHSHQMKMAATGPLAEQHCWSVEAAGQTGAEPTCSQATSTKVPSIGSTQTPESHQGKAESSRTKSRLLSNMPKLVIPSATTKFPPEITVTPPTPTLLSPKGSISEETKQKLKSAILSAQSAANVRKESLCQPALEVLETSSQESSLESETDEDDDYMMMDM", "length": 2193 }, "evidence": [ { "id": "A0A8V1ACV9", "url": "https://omabrowser.org/oma/group/A0A8V1ACV9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3X8Q1-1", "protein_name": "Calcineurin-binding protein cabin-1", "gene_name": "Cabin1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIRIAALNASSTIEDDHEGSFKSHKIQTKEAQEAEAFALYHKALDLQKHDRFEESAKAYHELLEARLLREAVSSGDEKEGLKHPGLILKYSTYKNLAQLAAQREDLETAMEFYLEAVMLDSTDVNLWYKIGHVALRLIRLPLARHAFEEGLRCNPDHWPCLDNLITVLYTLSDYTTCLYFICKALEKDCRYSKGLVLKEKIFEEQPCLRKDSLRMFLKCDMSIHDVSVSAAETQAIVDEALGLRKKRQALIVREKEPDLKLVQPIPFFTWKCLGESLLAMYSHLTTCEPPRPSLGKRIDLSDYQDPSQLLASSVVVTPVSVVQPSPICTNPTVAVAEPVLSYTSVTAASFPLHSPSLLDTGTPMGDVSGGDKSKKGVKRKKTVEESGETAKRRSARVRNTKCKKEEKVDFQGLLVKFLPSRLRKLDPEEEDDPFNNYEVQAEAKLESFSNVGPHRLSFDSATFMESEKQDVHAFLMENLTNGGLLELMMRYLKSMGHKFLLKWPPGLADVVLSVYHSWRRHSTSLPNPLLRDCSNKHIKDMMLMSLSCMELQLDQWLLTKGRSSAVSPRNCPAGVVTGRFGPDFPGTHCLGDLLQLSFASSQRDLFEDGWLEFVVRVYWLKARFLALQGDMEQALENYDICTEILQSSSAIQAQAGAEQGDIVIRLPNLHNDSVVSLEEIDKNLKSLERCQSLEEIQRLFEAGDYKAVVHLLRPTLCTSGFDRAKHLEFMTSIPERPAQLLLLQDSLLRLKDHRQCFECSDVALNEAVQQMLNSSESAAKEEWVATVTQLLLGIEQALSSDSSGSILKESSSTTGLVRLTNNLIQVIDCSMAVQEEPKEPYVSSVLPWIILHRIIWQEEDTFRSLCHQQQLQNPTEEGIPEMPMLPSSLMLLNTAHEYLGRRSWCCNSDGALLRFYVQVLQKELAASASEDTHPYKEELETALEQCFYCLYSFPSKKSKARYLEEHSAQQVDLIWEDALFMFEYFKPKTLPEFDSYKTSTVSADLANLLKRIATIVPRTEKPALSMDKVSAYIEGTSAEAPCLPEGADPTPPVLNELYYLLADYHFKNKEQSKAIKFYMHDICICPNRFDSWAGMALARASRIQDKLNSNELKSDGPIWKHATPVLNCFRRALEIDSSNLSLWIEYGTMSYALHSFASRQLKQWRSELPPELVQQMEDRRDSMLETARHCFTSAARCEGDGDEEEWLIHYMLGKVAEKQQQPPTVYLLHYRQAGHYLHEEAARYPKKIHYHNPPELAMEALEVYFRLHASILKLLGKPDSGVGAEVLVSFMKEAAEGPFARGEEKNTPKASEKEKACLVDEDSHSSAGTLPGPGASLPSSSGPGLTSPPYTATPIDHDYVKCKKPHQQAAPDDRSQDSTAVALSDSSSTQDFFNEPTSLLEGSRKLFPEKRLSGLSAQAGPSGKDLPGPTEERGKTEESLESTEAFRVVEQSVQKPVADSSASAYIPSKPPASTPPLWDGKKRGDSLGEPVAFPQGLPAGAEEQRQFLTEQCISSFCLCLSRFPQHYKSLYRLAFLYTYSKTHRNLQWARDVLLGSSIPWQQLQHMPAQGLFCERNKTNFFNGIWRIPVDEIDRPGSFAWHMNRSIVLLLKVLAQLRDHSTLLKVSSMLQRTPDQGKKYLRDADRQVLAQRAFILTVKVLEDTLSELAEGSEHPGSKACGLSGARMTTDVSHKASPEDGQESPQHPKKLPLADGSGPGPEPGGRMGPLNQLPVVTDIRDNTDQGGEQKDKESPQVGPTEPMDTSEAAGRHSDLEQTSRLLPGRPPRDRGPESRSAELSLEELSISTRQQPAPLAPSPAAPTTTAAPTTMAARGAGHSEEAPPRPNRKRKLLEDTESGKTLLLDAYRVWQQGQKGMAYDLSRIEKIMSETYMLIKQVDEETALEQAVKFCQVHLGAATQRQASGDTPTTPKHPKDSRENFFPATVVPTVPDPTAPDALQRPSDSHLKPVLATVITCPPSASASIPDLSTDPGIPRPHRPETTPSRAPLSPEGEEASGVTEGTSILPQEPRYSHQIKMAATGHLAEQHCWPVEVACQTGAEPTCSQASSTKVPSSGSTQTAESHQGKTESSRAKSRLLPNMPKLVIPSATTKSPPEITVTPPTPTLLSPKGSISEETKQKLKSAILSAQSAANVRKESLCQPALEVLETSSQESSLESETDEDDDFMDV", "length": 2187 }, "evidence": [ { "id": "A0A8V1ACV9", "url": "https://omabrowser.org/oma/group/A0A8V1ACV9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "O88480-1", "protein_name": "Calcineurin-binding protein cabin-1", "gene_name": "Cabin1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MIRIAALNASSTIEDDHEGSFKSHKIQTKEAQEAEAFALYHKALDLQKHDRFEESAKAYHELLEARLLREAVSSGDEKEGLKHPGLILKYSTYKNLAQLAAQREDLETAMEFYLEAVMLDSTDVNLWYKIGHVALRLIRLPLARHAFEEGLRCNPDHWPCLDNLITVLYTLSDYTTCLYFICKALEKDCRYSKGLVLKEKIFEEQPCLRKDSLRMFLKCDMSVHEVSVNAAETQAIVDEALGLRKKRQALIVREKEPDLKLVQPIPFFTWKCLGESLLAMYNHLTTCEPPRPSLGKRIDLSDYQDPSQLLAPSIVVTPVSVVQPSPVCTNPTVAVAEPVLSYTSVTTTSFPLHSPGLLDTGTPMGDVSGGDKSKKGVKRKKTLEESGETAKRRSARVRNTKCKKEEKVDFQGLLVKFLPSRLRKLDPEEEDDPFNNYEVQSEAKLESFSNVGPHRLSFDSATFMESEKQDVHAFLMENLTNGGVLELMMRYLKSMGHKFLLKWPPGLAEVVLSVYHSWRRHSTSLPNPLLRDCSNKHIKDMMLMSLSCMELQLDQWLLTKGRSSTVSPRNCPAGVVTGRFGPDFPGTHCLGDLLQLSFASSQRDLFEDGWLEFVVRVYWLKARFLALQGDMEQALENYDICTEILQSSTALQAQAGAEQRDIVIRLPNLHNDSIVSLEEIDKNLKSLERCQSLEEIQRLFEAGDYKAVVQLLRPTLCTSGFDRAKHLEFMTSIPERPAQLLLLQDSLLRLEEHRQCFECSDVALNEAVQQMLNSSDSAAKEEWAATVTQLLLGMEQALSSDSRGSILKESSSPTGLVRLTNNLIQVIDCSMAVQEEPKEPYVSSVLPWIILHRIIWQEEDTFRSLCHQQQLQNPTEEGISEMPMLPSSLMLLNTAHEYLGRRSWCCNSDGALLRFYVHVLQKELAASASEDTHPYKEELETALEQCFYCLYSFPSKKSKARYLEEHSAQQVDLTWEDALFMFEYFKPKTLPEFDSYKTSTVSADLANLLKRIATIVPRTEKPALSMDKVSAYIEGTSAEVPCLPDGADPAPPVLNELYYLLADYHFKNKEQSKAIKFYMHDICICPNRFDSWAGMALARASRIQDKLNSNELKSDGPIWRHATPVLNCFRRALEIDSSNLSLWIEYGTMSYALHSFASRQLKQWRAELPPEVVQQMEDRRDSMLETARHCFTSAAHCEGDGDEEEWLIHYMLGKVAEKQQQPPTVYLLHYRQAGHYLHEEAARYPKKIHYHNPPELAMEALEVYFRLHASILKLLGKPDSGVSAEVLVSFMKEAAEGPFARGEEKNTPKASEKEKACLVDEDSHSSAGTLPGPGASLPSSSGPGLTSPPYTATPIDHDYVKCKKPRQQATPDDRSQDSTAVALSDSSSTQDFFNEPTSLLDGSRKLLPEKRISGLSAQAGPSGKDLPGPTEERGKTEESLESTEAFRVVEPSVQKPVADSSASAYIPSKPAVSTPPPWDGKKRSDPLGEPVAFPQGLPAGAEEQRQFLTEQCIASFCLCLSRFPQHYKSLYRLAFLYTYSKTHRNLQWARDVLLGSSIPWQQLQHMPAQGLFCERNKTNFFNGIWRIPVDEIDRPGSFAWHMNRSIVLLLKVLAQLRDHSTLLKVSSMLQRTPDQGKKYLRDADRQVLAQRAFILTVKVLEDTLSELAEGLEHPGSKACGLSGARMTTDVSHKASPEDGQESLPHPKKLPLADGSGPGPEPGGKVGPLHQLPVATDTRDNTEQGGEPKDKERPPVGPTEPMDTGETAARHPDLEPTPRLLPGRPPRDRGPESRSAELSLEELSISTRQQPAPLVPSPVTPTTAAPTTMGARAAGHPEEAPPRPNRKRKLLQDTESGKTLLLDAYRVWQQGQKAMAYDLSRIEKIMSETYMLIKQVDEETALEQAVKFCQVHLGAAAQRQASGDAPTTPKHPKDSRENFFPATVAPSAPDTTAPDALQRPSDSHLKPGLAAAITCPPSASASTPDPGIPQPHRPEAVPSRAPLSPDGEEVSGVTEGPSFLSQEPRHSHQMKMAATGPLAEQHCWPVEAACQTGAEPTFSQATSTKVPSSGSTQTPESHQGKTESSRAKSRLLPNMPKLVIPSATTKFPPEITVTPPTPTLLSPKGSISEETKQKLKSAILSAQSAANVRKESLCQPALEVLETSSQESSLESETDEDDDFMDV", "length": 2182 }, "evidence": [ { "id": "A0A8V1ACV9", "url": "https://omabrowser.org/oma/group/A0A8V1ACV9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACV9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACV9" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACV9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACV9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "chromatin organization", "id": "GO:0006325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006325", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACV9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACV9" } ], "pmid": "" }, { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACV9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACV9" } ], "pmid": "" }, { "name": "nucleosome assembly", "id": "GO:0006334", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006334", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACV9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACV9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "transcription corepressor activity", "id": "GO:0003714", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003714", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACV9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACV9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 10, "end_pos": 12, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1137, "end_pos": 1139, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1575, "end_pos": 1577, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1602, "end_pos": 1604, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1691, "end_pos": 1693, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2077, "end_pos": 2079, "annotation": "n_glycosylation_sequon" }, { "start_pos": 229, "end_pos": 231, "annotation": "n_glycosylation_sequon" }, { "start_pos": 567, "end_pos": 569, "annotation": "n_glycosylation_sequon" }, { "start_pos": 774, "end_pos": 776, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1ACV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACV9" }, { "id": "PF09047", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09047" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Calcineurin-binding protein cabin-1 MEF2-binding", "eco_id": "ECO_0000259", "start_pos": 2116, "end_pos": 2150, "start_aa": "Thr", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 327, 1928 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 10, "end_pos": 12 }, { "start_pos": 1137, "end_pos": 1139 }, { "start_pos": 1575, "end_pos": 1577 }, { "start_pos": 1602, "end_pos": 1604 }, { "start_pos": 1691, "end_pos": 1693 }, { "start_pos": 2077, "end_pos": 2079 }, { "start_pos": 229, "end_pos": 231 }, { "start_pos": 567, "end_pos": 569 }, { "start_pos": 774, "end_pos": 776 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": 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"phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1ADC3-1", "uniprot_ac": "A0A8V1ADC3", "uniprot_id": "A0A8V1ADC3_CHICK", "mass": { "chemical_mass": 45391.0, "monoisotopic_mass": 45391.0 }, "refseq": { "ac": "NP_001304017", "name": "perilipin-4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001304017" }, "gene_names": [ { "name": "PLIN4", "type": "recommended", "evidence": [ { "id": "A0A8V1ADC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADC3" } ] }, { "name": "PLIN4", "type": "synonym", "evidence": [ { "id": "NP_001304017", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001304017" } ] } ], "protein_names": [ { "name": "Perilipin", "type": "recommended", "evidence": [ { "id": "A0A8V1ADC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADC3/entry#names_and_taxonomy" } ] }, { "name": "perilipin-4", "type": "synonym", "evidence": [ { "id": "NP_001304017", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001304017" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: HAEL01004047.1, BX929460.2 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000375.1. On Sep 23, 2021 this sequence version replaced NP_001304017.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001304017", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001304017" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADC3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADC3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PLIN4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADC3", "locus": { "chromosome": "28", "start_pos": 2975636, "end_pos": 2977859, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027214", "url": "https://www.ensembl.org/id/ENSGALG00010027214" } ] } } ], "crossref": [ { "id": "A0A8V1ADC3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1ADC3", "database": "AlphaFoldDB", "categories": [] }, { "id": "100857433", "url": "https://www.ncbi.nlm.nih.gov/gene/100857433", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004279", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004279", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:100857433", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100857433", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VMFRGIT", "url": "https://omabrowser.org/oma/group/VMFRGIT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A7X9", "url": "https://www.orthodb.org/?gene=A0A8V1A7X9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ADC3", "url": "https://www.orthodb.org/?gene=A0A8V1ADC3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14024", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14024", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14024:SF11", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14024:SF11", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03036", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03036", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-163560", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-163560", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-6811440", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6811440", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9706019", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9706019", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001304017", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001304017", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1A7X9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7X9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A7X9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7X9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ADC3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADC3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ADC3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADC3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAASEDGAAQPKAEEQQQSIGTRVANLPLVSSACGIVSSAYNSTKGSHPYVRSVCDAAEKGVRTLTAAAVSGAQPILTKLEPQISTANEYACKGLDKLEEKLPILQQPTEKLISDTKQLVTSTVTGARDVLTSTVAGAKDAVSSRVTGVMDMTKGAVQGSVELTKSAVSSGVTTVMGSTVGQMVASGVGSMLEKSEELVDHYLPMTDEELAKLATAVEGFEPEQQKKQQSYFVRLGSLSAKLQHRALQHSLGKLQSARSSSHDVLGQLQRALDLVEHLKQGVDQKLQGGQEKLQQLWLEWSTKQPGGGKELVPPATVESGVLALLQGLAQQLHSTCQPLVCSLQGLPASIQDTAAQVRHNVEELRASLTSATSLQELTGSAVARARVHATKARELMDELVEHVAHNTPLSWLVGPFAPSVQQGQSVQGE", "length": 429, "header": "tr|A0A8V1ADC3-1|A0A8V1ADC3_CHICK Isoform 1 of Perilipin OS=Gallus gallus OX=9031 GN=PLIN4 PE=1 SV=1 CANONICAL=A0A8V1ADC3-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A7X9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADC3/entry#A0A8V1A7X9-1", "sequence": { "sequence": "MAASEDGAAQPKAEEQQQSIGTRVANLPLVSSACGIVSSAYNSTKGSHPYVRSVCDAAEKGVRTLTAAAVSGAQPILTKLEPQISTANEYACKGLDKLEEKLPILQQPTEKLVTSTVTGARDVLTSTVAGAKDAVSSRVTGVMDMTKGAVQGSVELTKSAVSSGVTTVMGSTVGQMVASGVGSMLEKSEELVDHYLPMTDEELAKLATAVEGFEPEQQKKQQSYFVRLGSLSAKLQHRALQHSLGKLQSARSSSHDVLGQLQRALDLVEHLKQGVDQKLQGGQEKLQQLWLEWSTKQPGGGKELVPPATVESGVLALLQGLAQQLHSTCQPLVCSLQGLPASIQDTAAQVRHNVEELRASLTSATSLQELTGSAVARARVHATKARELMDELVEHVAHNTPLSWLVGPFAPSVQQGQSVQGE", "length": 422, "header": "tr|A0A8V1A7X9-1|A0A8V1ADC3_CHICK Computationally mapped isoform of Perilipin OS=Gallus gallus OX=9031 GN=PLIN4 PE=1 SV=1 CANONICAL=A0A8V1ADC3-1" }, "locus": { "chromosome": "28", "start_pos": 2977852, "end_pos": 2975971, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065977.1", "url": "https://www.ensembl.org/id/ENSGALT00010065977.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040243.1", "url": "https://www.ensembl.org/id/ENSGALP00010040243.1" } ] } }, { "isoform_ac": "A0A8V1ADC3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADC3/entry#A0A8V1ADC3-1", "sequence": { "sequence": "MAASEDGAAQPKAEEQQQSIGTRVANLPLVSSACGIVSSAYNSTKGSHPYVRSVCDAAEKGVRTLTAAAVSGAQPILTKLEPQISTANEYACKGLDKLEEKLPILQQPTEKLISDTKQLVTSTVTGARDVLTSTVAGAKDAVSSRVTGVMDMTKGAVQGSVELTKSAVSSGVTTVMGSTVGQMVASGVGSMLEKSEELVDHYLPMTDEELAKLATAVEGFEPEQQKKQQSYFVRLGSLSAKLQHRALQHSLGKLQSARSSSHDVLGQLQRALDLVEHLKQGVDQKLQGGQEKLQQLWLEWSTKQPGGGKELVPPATVESGVLALLQGLAQQLHSTCQPLVCSLQGLPASIQDTAAQVRHNVEELRASLTSATSLQELTGSAVARARVHATKARELMDELVEHVAHNTPLSWLVGPFAPSVQQGQSVQGE", "length": 429, "header": "tr|A0A8V1ADC3-1|A0A8V1ADC3_CHICK Isoform 1 of Perilipin OS=Gallus gallus OX=9031 GN=PLIN4 PE=1 SV=1 CANONICAL=A0A8V1ADC3-1" }, "locus": { "chromosome": "28", "start_pos": 2977852, "end_pos": 2975971, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065978.1", "url": "https://www.ensembl.org/id/ENSGALT00010065978.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040244.1", "url": "https://www.ensembl.org/id/ENSGALP00010040244.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:100857433", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100857433", "resource": "KEGG Pathway" }, { "id": "R-GGA-163560", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-163560", "resource": "Reactome", "description": "Triglyceride catabolism" }, { "id": "R-GGA-6811440", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6811440", "resource": "Reactome", "description": "Retrograde transport at the Trans-Golgi-Network" }, { "id": "R-GGA-9706019", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9706019", "resource": "Reactome", "description": "RHOBTB3 ATPase cycle" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A286ZIN9-1", "protein_name": "Perilipin", "gene_name": "PLIN3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSASETEASASSTQVTTEEPVQQPSVVDRVAGMPLISSTCHMVSAAYTSTKESHPHVKTVCDVAEKGVKTLTAAAVSGAQPILSKLEPQLTSASEYAHRGLDKLEENLPILQQPSEKVLADTKELVSSKVSEAREAVSNTVSSAKDTVASRVTEAVDVTRGAVQSGVDLTKSMVTSSVHSVMGSRVGQMVLSGVDTVLGKSEEWVDNHLPMTDAELAHLATSLEGFDMASVAQQRQDQSYFVRLGSLSERLRQRAYEHSLGKLQHTRQRAQEALLQLSQALSLMETVKQGVDQKLVEGQEKLHQMWLSWNQKRLQGGEEDPAKPEVESQTFTMFRDVTQQLQTTCASLGASLQGLPAHVKEQALQARRQVEDLQATFSGMHSFQDLSSNVLMQSREQVARAREALDHVVDYVAQNTPVMWLVGPFAPGVVEKAPEEKK", "length": 438 }, "evidence": [ { "id": "A0A8V1ADC3", "url": "https://omabrowser.org/oma/group/A0A8V1ADC3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1QGJ3-1", "protein_name": "Perilipin", "gene_name": "plin3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MADNVKTAEKDKEDSQEQQSVISRVGNLPLVSSACGAVYNAYSSTKDSVPLLKGVMEVAESGVRTLGAAASTGSKPILDRLEPQIAAVNEYAIKGLEKVEGNLPILQQPADKLVSDTVGMVYQSVTGAKDAVVGAVMEGVEKTRMAVTGGINTVMGSRVGQMVSNGVDKALTHSEDWVEQNLPISEKELATLAEPRPGEEEGFIVSTRSSYFVRLGKLSAKVRERALEQSLLRARKARDTTHASVTQMTSTMDLLESARVTLTSANQQLAGAPEQLLQRWKEWKEGQPKELQEKVTAETEADGAKDKEQEMESKALLMVRGLSDQLKTACSGVVSSVQGLPGTVQEQLLNARRTAGELQASLSGTKTLTPVLLLQTRQQIGQVRQSLDGVVEYLLNNTPLNWLVGPFAPQITEKGE", "length": 416 }, "evidence": [ { "id": "A0A8V1ADC3", "url": "https://omabrowser.org/oma/group/A0A8V1ADC3/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "G3HCI0-1", "protein_name": "Perilipin", "gene_name": "Plin3", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSSNGTDAPAEAQAAVEEPVPQPSVVDRMASLPLISSTCEMVSAAYTSTKDRYPHVRTVCDVAEKGVKTLTAAAVSGAQPILSKLEPQIASASEYAHRGLDRLQESLPILQQPTEKVLADTKELVSSTVSGAKEIVSSSVTSAKDTVATRVTGAVDVTRGAVQSTMDMTKSAVTSGVQSVLGSRVGQMVIGGVDSMLVKSEAWADNRLPLTDAELALIATSPEGSDLASLQQQRQERNYFVRLGSLSERLRNHAYEHSLGKLRSARQNAHEALQQLTHALSLMESVKQGMDQRLGEGQEKLHHMWLSWNQKKPQDAEKDAAKPEQVEARALSMLRDITQQLQSTCVALGASIQGLPGHIREQAQQARSQVEDLQATFSGIHSFQDLTAGVLAQTRERIARAREALDHTVEYVAQNTPVTWLVGPFAPGITEKPLEEEKQG", "length": 440 }, "evidence": [ { "id": "A0A8V1ADC3", "url": "https://omabrowser.org/oma/group/A0A8V1ADC3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "lipid droplet", "id": "GO:0005811", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005811", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADC3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADC3" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADC3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADC3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "positive regulation of triglyceride storage", "id": "GO:0010890", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010890", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADC3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADC3" } ], "pmid": "" }, { "name": "lipid storage", "id": "GO:0019915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019915", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADC3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADC3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 42, "end_pos": 44, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 42, "end_pos": 44 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1ADI6-1", "uniprot_ac": "A0A8V1ADI6", "uniprot_id": "A0A8V1ADI6_CHICK", "mass": { "chemical_mass": 114658.0, "monoisotopic_mass": 114658.0 }, "refseq": {}, "gene_names": [ { "name": "LRIG2", "type": "recommended", "evidence": [ { "id": "A0A8V1ADI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADI6" } ] } ], "protein_names": [ { "name": "Leucine rich repeats and immunoglobulin like domains 2", "type": "synonym", "evidence": [ { "id": "A0A8V1ADI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADI6/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADI6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADI6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LRIG2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADI6", "locus": { "chromosome": "26", "start_pos": 3693729, "end_pos": 3677447, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027245", "url": "https://www.ensembl.org/id/ENSGALG00010027245" } ] } } ], "crossref": [ { "id": "A0A8V1ADI6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1ADI6", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd05763", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05763", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000483", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000483", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003591", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003591", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013098", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013098", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050467", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050467", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A843", "url": "https://www.orthodb.org/?gene=A0A8V1A843", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AAQ9", "url": "https://www.orthodb.org/?gene=A0A8V1AAQ9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ADI6", "url": "https://www.orthodb.org/?gene=A0A8V1ADI6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45842", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45842", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45842:SF23", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45842:SF23", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01463", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01463", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07679", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07679", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13855", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13855", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13927", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13927", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1A843", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A843", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A843-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A843-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AAQ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAQ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AAQ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAQ9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ADI6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADI6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ADI6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADI6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEQQPQLSHWQFIDHTVLFTLCSATHQCASHRTAVTRDLSHNRISSSNWSMDLSAHTLQEVKMNYNELSEIPYFGETTSNITLLSLVHNAIPEINAEQLQVYLSLENLDLSSNLISEIKAASFPRMQLKYLNLSNNRITTLEAGCLDNLSSSLIVLKLNRNRISVIPPKIFKLPHVQFLELKRNRIKIVESLTFQGLESLKSLKMQRNGISRLMDGAFFGLNSIEELELEHNNLTEVNKGWLYGLRTLQQLFVSQNAINKISPDAWEFCQRLAELDLSYNQLTRLRESAFVGLGLLEKLNLGDNRISHIADGVFRGLTNLRALDLGNNEISWAIEDANEAFVGLSRLDKLILQGNQIKSITKKAFSGLEGLEHLDLSNNAVMSIQENAFAQAQLKELILNTSSLLCDCQLKWLPQWLTDSHLQQAVNVSCAHPEWLAGQSLFSVDPDDFVCDNFPKPQIRVHPETTIALRGMNVTLTCTAVSSSDSPMSTAWRKDSEVLYDAEVENFARYQQQNGEIVEYTTVLHLFNVNFTDEGKYQCIVTNHFGSNYSDKAKLTVNELPSFLKTPMDLTIRTGAMARLECAAEGHPTPQISWQKDGGTDFPAARERRMHVMPEDDVFFIANVKIEDMGIYSCMAQNAAGGLSANATLTVLETPSFIRPLEDRTVTRGETAVLQCIAGGSPAPRLNWTKDDGPLAVTERHFFAAANQLLIIVDAGLEDAGKYTCIMSNTLGTERGHIYLHVLASPNCDSSQSGIVHEEDGWTTVGVVIIVVVCCVVGTSLVWVIVIYHMRRKSEDYSITNTEEMNLPADIPSYLSSQGTLSEPQEGYSNSEAGSHQQLMPPASGYVHKGTDGGTAPLVICSDCYDNANIYSRTREYCPYTYITEEDPLDQTLPNLMVQMPKETYPAHTQHETSALDNVFGDRDMSVFLTGHDRISEKKIPSQQINEPFQLPLWAVNKDLALSHSHFLHQQSAREAPRPLRTEGIIDSEREQAASPRPFHRLREHNFDFNRTRNIRDYNETT", "length": 1022, "header": "tr|A0A8V1ADI6-1|A0A8V1ADI6_CHICK Isoform 1 of Leucine rich repeats and immunoglobulin like domains 2 OS=Gallus gallus OX=9031 GN=LRIG2 PE=4 SV=1 CANONICAL=A0A8V1ADI6-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A843-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADI6/entry#A0A8V1A843-1", "sequence": { "sequence": "MQPHICCKQQDLSHNRISSSNWSMDLSAHTLQEVKMNYNELSEIPYFGETTSNITLLSLVHNAIPEINAEQLQVYLSLENLDLSSNLISEIKAASFPRMQLKYLNLSNNRITTLEAGCLDNLSSSLIVLKLNRNRISVIPPKIFKLPHVQFLELKRNRIKIVESLTFQGLESLKSLKMQRNGISRLMDGAFFGLNSIEELELEHNNLTEVNKGWLYGLRTLQQLFVSQNAINKISPDAWEFCQRLAELDLSYNQLTRLRESAFVGLGLLEKLNLGDNRISHIADGVFRGLTNLRALDLGNNEISWAIEDANEAFVGLSRLDKLILQGNQIKSITKKAFSGLEGLEHLDLSNNAVMSIQENAFAQAQLKELILNTSSLLCDCQLKWLPQWLTDSHLQQAVNVSCAHPEWLAGQSLFSVDPDDFVCDNFPKPQIRVHPETTIALRGMNVTLTCTAVSSSDSPMSTAWRKDSEVLYDAEVENFARYQQQNGEIVEYTTVLHLFNVNFTDEGKYQCIVTNHFGSNYSDKAKLTVNELPSFLKTPMDLTIRTGAMARLECAAEGHPTPQISWQKDGGTDFPAARERRMHVMPEDDVFFIANVKIEDMGIYSCMAQNAAGGLSANATLTVLETPSFIRPLEDRTVTRGETAVLQCIAGGSPAPRLNWTKDDGPLAVTERHFFAAANQLLIIVDAGLEDAGKYTCIMSNTLGTERGHIYLHVLASPNCDSSQSGIVHEEDGWTTVGVVIIVVVCCVVGTSLVWVIVIYHMRRKSEDYSITNTEEMNLPADIPSYLSSQGTLSEPQEGYSNSEAGSHQQLMPPASGYVHKGTDGGTAPLVICSDCYDNANIYSRTREYCPYTYITEEDPLDQTLPNLMVQMPKETYPAHTQHETSALDNVFGDRDMSVFLTGHDRISEKKIPSQQINEPFQLPLWAVNKDLALSHSHFLHQQSAREAPRPLRTEGIIDSEREQAASPRPFHRLREHNFDFNRTRNIRDYNETT", "length": 995, "header": "tr|A0A8V1A843-1|A0A8V1ADI6_CHICK Computationally mapped isoform of Leucine rich repeats and immunoglobulin like domains 2 OS=Gallus gallus OX=9031 GN=LRIG2 PE=4 SV=1 CANONICAL=A0A8V1ADI6-1" }, "locus": { "chromosome": "26", "start_pos": 3693232, "end_pos": 3678564, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066054.1", "url": "https://www.ensembl.org/id/ENSGALT00010066054.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040320.1", "url": "https://www.ensembl.org/id/ENSGALP00010040320.1" } ] } }, { "isoform_ac": "A0A8V1AAQ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADI6/entry#A0A8V1AAQ9-1", "sequence": { "sequence": "MDAQRSAGRNEEPRPATARRDLSHNRISSSNWSMDLSAHTLQEVKMNYNELSEIPYFGETTSNITLLSLVHNAIPEINAEQLQVYLSLENLDLSSNLISEIKAASFPRMQLKYLNLSNNRITTLEAGCLDNLSSSLIVLKLNRNRISVIPPKIFKLPHVQFLELKRNRIKIVESLTFQGLESLKSLKMQRNGISRLMDGAFFGLNSIEELELEHNNLTEVNKGWLYGLRTLQQLFVSQNAINKISPDAWEFCQRLAELDLSYNQLTRLRESAFVGLGLLEKLNLGDNRISHIADGVFRGLTNLRALDLGNNEISWAIEDANEAFVGLSRLDKLILQGNQIKSITKKAFSGLEGLEHLDLSNNAVMSIQENAFAQAQLKELILNTSSLLCDCQLKWLPQWLTDSHLQQAVNVSCAHPEWLAGQSLFSVDPDDFVCDNFPKPQIRVHPETTIALRGMNVTLTCTAVSSSDSPMSTAWRKDSEVLYDAEVENFARYQQQNGEIVEYTTVLHLFNVNFTDEGKYQCIVTNHFGSNYSDKAKLTVNELPSFLKTPMDLTIRTGAMARLECAAEGHPTPQISWQKDGGTDFPAARERRMHVMPEDDVFFIANVKIEDMGIYSCMAQNAAGGLSANATLTVLETPSFIRPLEDRTVTRGETAVLQCIAGGSPAPRLNWTKDDGPLAVTERHFFAAANQLLIIVDAGLEDAGKYTCIMSNTLGTERGHIYLHVLASPNCDSSQSGIVHEEDGWTTVGVVIIVVVCCVVGTSLVWVIVIYHMRRKSEDYSITNTEEMNLPADIPSYLSSQGTLSEPQEGYSNSEAGSHQQLMPPASGYVHKGTDGGTAPLVICSDCYDNANIYSRTREYCPYTYITEEDPLDQTLPNLMVQMPKETYPAHTQHETSALDNVFGDRDMSVFLTGHDRISEKKIPSQQINEPFQLPLWAVNKDLALSHSHFLHQQSAREAPRPLRTEGIIDSEREQAASPRPFHRLREHNFDFNRTRNIRDYNETT", "length": 1005, "header": "tr|A0A8V1AAQ9-1|A0A8V1ADI6_CHICK Computationally mapped isoform of Leucine rich repeats and immunoglobulin like domains 2 OS=Gallus gallus OX=9031 GN=LRIG2 PE=4 SV=1 CANONICAL=A0A8V1ADI6-1" }, "locus": { "chromosome": "26", "start_pos": 3693232, "end_pos": 3677670, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066056.1", "url": "https://www.ensembl.org/id/ENSGALT00010066056.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040322.1", "url": "https://www.ensembl.org/id/ENSGALP00010040322.1" } ] } }, { "isoform_ac": "A0A8V1ADI6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADI6/entry#A0A8V1ADI6-1", "sequence": { "sequence": "MEQQPQLSHWQFIDHTVLFTLCSATHQCASHRTAVTRDLSHNRISSSNWSMDLSAHTLQEVKMNYNELSEIPYFGETTSNITLLSLVHNAIPEINAEQLQVYLSLENLDLSSNLISEIKAASFPRMQLKYLNLSNNRITTLEAGCLDNLSSSLIVLKLNRNRISVIPPKIFKLPHVQFLELKRNRIKIVESLTFQGLESLKSLKMQRNGISRLMDGAFFGLNSIEELELEHNNLTEVNKGWLYGLRTLQQLFVSQNAINKISPDAWEFCQRLAELDLSYNQLTRLRESAFVGLGLLEKLNLGDNRISHIADGVFRGLTNLRALDLGNNEISWAIEDANEAFVGLSRLDKLILQGNQIKSITKKAFSGLEGLEHLDLSNNAVMSIQENAFAQAQLKELILNTSSLLCDCQLKWLPQWLTDSHLQQAVNVSCAHPEWLAGQSLFSVDPDDFVCDNFPKPQIRVHPETTIALRGMNVTLTCTAVSSSDSPMSTAWRKDSEVLYDAEVENFARYQQQNGEIVEYTTVLHLFNVNFTDEGKYQCIVTNHFGSNYSDKAKLTVNELPSFLKTPMDLTIRTGAMARLECAAEGHPTPQISWQKDGGTDFPAARERRMHVMPEDDVFFIANVKIEDMGIYSCMAQNAAGGLSANATLTVLETPSFIRPLEDRTVTRGETAVLQCIAGGSPAPRLNWTKDDGPLAVTERHFFAAANQLLIIVDAGLEDAGKYTCIMSNTLGTERGHIYLHVLASPNCDSSQSGIVHEEDGWTTVGVVIIVVVCCVVGTSLVWVIVIYHMRRKSEDYSITNTEEMNLPADIPSYLSSQGTLSEPQEGYSNSEAGSHQQLMPPASGYVHKGTDGGTAPLVICSDCYDNANIYSRTREYCPYTYITEEDPLDQTLPNLMVQMPKETYPAHTQHETSALDNVFGDRDMSVFLTGHDRISEKKIPSQQINEPFQLPLWAVNKDLALSHSHFLHQQSAREAPRPLRTEGIIDSEREQAASPRPFHRLREHNFDFNRTRNIRDYNETT", "length": 1022, "header": "tr|A0A8V1ADI6-1|A0A8V1ADI6_CHICK Isoform 1 of Leucine rich repeats and immunoglobulin like domains 2 OS=Gallus gallus OX=9031 GN=LRIG2 PE=4 SV=1 CANONICAL=A0A8V1ADI6-1" }, "locus": { "chromosome": "26", "start_pos": 3693232, "end_pos": 3679124, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066055.1", "url": "https://www.ensembl.org/id/ENSGALT00010066055.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040321.1", "url": "https://www.ensembl.org/id/ENSGALP00010040321.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADI6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADI6" } ], "pmid": "" }, { "name": "intracellular vesicle", "id": "GO:0097708", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097708", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADI6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADI6" } ], "pmid": "" }, { "name": "growth cone", "id": "GO:0030426", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030426", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADI6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADI6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "signaling receptor binding", "id": "GO:0005102", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005102", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADI6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADI6" } ], "pmid": "" }, { "name": "signaling receptor activity", "id": "GO:0038023", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038023", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADI6", "url": 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"tr|A0A8V1ADD5-1|A0A8V1ADD5_CHICK Isoform 1 of Hyaluronan and proteoglycan link protein 2 OS=Gallus gallus OX=9031 GN=HAPLN2 PE=3 SV=1 CANONICAL=A0A8V1ADD5-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A8A2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADD5/entry#A0A8V1A8A2-1", "sequence": { "sequence": "HSTDLSFPHPFILRWGGCDRARTQAVVDGRSSSPGDATPRLQYLLEPLHTAVHTQRGATATLPCVLRALPRNYRVKWSKVEPANYGESVIIITNGLYHKNYGPLSPRVRLRHSHRYDASLTITNVALEDEGRYRCQLVNGLEDESVSLTLHLEGVVFPYQPSNGRYRFNYHEAKRACEQQDARLATYQQLYKAWMEGLDWCNAGWVLDGTVHYPIINSREPCGGRLLLPGIRSYGAKDKQRDRFDAFCFTSALQGEVYFIRGHLSFKEAGQACRNHGATIAKVGQLYSAWKFLGLDRCDGGWLADGSVRYPITTPRQRCGGLPEPGVHSFGFPRKELRTYGTYCFVGT", "length": 348, "header": "tr|A0A8V1A8A2-1|A0A8V1ADD5_CHICK Computationally mapped isoform of Hyaluronan and proteoglycan link protein 2 OS=Gallus gallus OX=9031 GN=HAPLN2 PE=3 SV=1 CANONICAL=A0A8V1ADD5-1" }, "locus": { "chromosome": "25", "start_pos": 992506, "end_pos": 990540, "strand": "-", "evidence": [ { "database": "Ensembl 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"start_pos": 992506, "end_pos": 990771, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068598.1", "url": "https://www.ensembl.org/id/ENSGALT00010068598.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042184.1", "url": "https://www.ensembl.org/id/ENSGALP00010042184.1" } ] } }, { "isoform_ac": "A0A8V1AK41-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADD5/entry#A0A8V1AK41-1", "sequence": { "sequence": "MIAAHVPAASPGLSCCVALTPSLPPGFLQSPALKMHRVLFASLWLLAASPTSSIFQKPTGSPATPRLQYLLEPLHTAVHTQRGATATLPCVLRALPRNYRVKWSKVEPANYGESVIIITNGLYHKNYGPLSPRVRLRHSHRYDASLTITNVALEDEGRYRCQLVNGLEDESVSLTLHLEGVVFPYQPSNGRYRFNYHEAKRACEQQDARLATYQQLYKAWMEGLDWCNAGWVLDGTVHYPIINSREPCGGRLLLPGIRSYGAKDKQRDRFDAFCFTSALQGEVYFIRGHLSFKEAGQACRNHGATIAKVGQLYSAWKFLGLDRCDGGWLADGSVRYPITTPRQRCGGLPEPGVHSFGFPRKELRTYGTYCFVGT", "length": 374, "header": "tr|A0A8V1AK41-1|A0A8V1ADD5_CHICK Computationally mapped isoform of Hyaluronan and proteoglycan link protein 2 OS=Gallus gallus OX=9031 GN=HAPLN2 PE=3 SV=1 CANONICAL=A0A8V1ADD5-1" }, "locus": { "chromosome": "25", "start_pos": 992506, "end_pos": 990771, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068596.1", "url": "https://www.ensembl.org/id/ENSGALT00010068596.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042183.1", "url": "https://www.ensembl.org/id/ENSGALP00010042183.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 51, "start_aa": "Thr", "end_pos": 51, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr51", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:425975", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:425975", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1RP37-1", "protein_name": "Hyaluronan and proteoglycan link protein 2", "gene_name": "HAPLN2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MQGRLSLPTLCHFLLPWAFTTLHRTLGDPASHPGPHYLLPPIHEVIHSRRGATTTLPCVLGAPPPSYKVRWSKVEPGELRETPILITNGLQARGYGPLGGRARMRRGHRLDASLVIAGVRLEDEGRYRCELINGIEDESVALTLRLEGVVFPYQPSRGRYQFNYYEAKQACEEQDGRLATYSQLYQAWTEGLDWCNAGWLLEGSVRYPVLTARAPCGGRGRPGIRSYGPRDRKRDRYDAFCFTSALTGHVFFVPGRLTLSEAHAACRRRGATVAKVGHLYAAWKFSGLDQCDGGWLADGSVRFPITTPRPRCGGLPDPGVRSFGFPRPQQAAYGTYCYSE", "length": 340 }, "evidence": [ { "id": "A0A8V1ADD5", "url": "https://omabrowser.org/oma/group/A0A8V1ADD5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q9ESM2-1", "protein_name": "Hyaluronan and proteoglycan link protein 2", "gene_name": "Hapln2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPSWIPLPAFCCLLLPWAFTVFHKTLGNPAPHPGPHYLLPPIHEVIHSRRGATATLPCVLGTSPPSYKVRWSKVEPGELRETLILITNGLHARDYGLLGGRASLRRGHRLDASLIIKNVRLEDEGRYRCELINGIEDESVALTLRLEGVVFPYQPSRGRYQFNYFEAKRACEEQDGRLATYSQLYQAWTEGLDWCNAGWLLEGSVRYPVLNARAPCGGHGRPGIRSYGPRDRSRDRYDAFCFTSALAGQVFFVPGRLTLSEAHAVCRRRGAVVAKVGHLYAAWKFSGLDRCDGGWLADGSVRFPITTPRPRCGGLPDPGVRSFGFPRPQQAAYGTYCYAEK", "length": 341 }, "evidence": [ { "id": "A0A8V1ADD5", "url": "https://omabrowser.org/oma/group/A0A8V1ADD5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9ESM3-1", "protein_name": "Hyaluronan and proteoglycan link protein 2", "gene_name": "Hapln2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPSRIPLPAFCCFLLPWAFTSFHKALGNPAPHPGPHYLLPPIHEVIHSRRGATATLPCVLGTSPPSYKVRWSKVEPGELRETLILITNGLHARDYGLLGGRASLRRGHRLDASLIIKNVRLEDEGRYRCELINGIEDESVALTLRLEGVVFPYQPSRGRYQFNYFEAKRACEEQDGRLATYGQLYQAWTEGLDWCNAGWLLEGSVRYPVLTARAPCGGHGRPGIRSYGPRDRSRDRYDAFCFTSALAGQVFFVPGRLTLSEAHAACRRRGAVVAKVGHLYAAWKFSGLDQCDGGWLADGSVRFPITTPRPRCGGLPDPGVRSFGFPRPQQASYGTYCYAEK", "length": 341 }, "evidence": [ { "id": "A0A8V1ADD5", "url": "https://omabrowser.org/oma/group/A0A8V1ADD5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9GZV7-1", "protein_name": "Hyaluronan and proteoglycan link protein 2", "gene_name": "HAPLN2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPGWLTLPTLCRFLLWAFTIFHKAQGDPASHPGPHYLLPPIHEVIHSHRGATATLPCVLGTTPPSYKVRWSKVEPGELRETLILITNGLHARGYGPLGGRARMRRGHRLDASLVIAGVRLEDEGRYRCELINGIEDESVALTLSLEGVVFPYQPSRGRYQFNYYEAKQACEEQDGRLATYSQLYQAWTEGLDWCNAGWLLEGSVRYPVLTARAPCGGRGRPGIRSYGPRDRMRDRYDAFCFTSALAGQVFFVPGRLTLSEAHAACRRRGAVVAKVGHLYAAWKFSGLDQCDGGWLADGSVRFPITTPRPRCGGLPDPGVRSFGFPRPQQAAYGTYCYAEN", "length": 340 }, "evidence": [ { "id": "A0A8V1ADD5", "url": "https://omabrowser.org/oma/group/A0A8V1ADD5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADD5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADD5" } ], "pmid": "" }, { "name": "central nervous system development", "id": "GO:0007417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007417", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADD5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADD5" } ], "pmid": "" }, { "name": "skeletal system development", "id": "GO:0001501", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001501", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADD5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADD5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "hyaluronic acid binding", "id": "GO:0005540", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005540", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADD5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADD5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADD5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADD5" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADD5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADD5" } ], "pmid": "" }, { "name": "perineuronal net", "id": "GO:0072534", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072534", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADD5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADD5" } ], "pmid": "" }, { "name": "gel phase of interstitial matrix", "id": "GO:0140150", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140150", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADD5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADD5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1ADD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADD5" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 65, "end_pos": 173, "start_aa": "Pro", "end_aa": "Ser", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1ADD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADD5" }, { "id": "PS50963", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50963" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Link", "eco_id": "ECO_0000259", "start_pos": 181, "end_pos": 276, "start_aa": "Val", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 51 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1ADC0-1", "uniprot_ac": "A0A8V1ADC0", "uniprot_id": "A0A8V1ADC0_CHICK", "mass": { "chemical_mass": 184914.0, "monoisotopic_mass": 184914.0 }, "refseq": { "ac": "XP_003640722", "name": "deleted in lung and esophageal cancer protein 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003640722" }, "gene_names": [ { "name": "DLEC1", "type": "recommended", "evidence": [ { "id": "A0A8V1ADC0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADC0" } ] }, { "name": "DLEC1", "type": "synonym", "evidence": [ { "id": "XP_003640722", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003640722" } ] } ], "protein_names": [ { "name": "DLEC1 cilia and flagella associated protein", "type": "synonym", "evidence": [ { "id": "A0A8V1ADC0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADC0/entry#names_and_taxonomy" } ] }, { "name": "deleted in lung and esophageal cancer protein 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003640722", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003640722" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052533.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_003640722.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003640722", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003640722" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADC0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADC0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "DLEC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADC0", "locus": { "chromosome": "2", "start_pos": 4723264, "end_pos": 4686637, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010026458", "url": "https://www.ensembl.org/id/ENSGALG00010026458" } ] } } ], "crossref": [ { "id": "420418", "url": "https://www.ncbi.nlm.nih.gov/gene/420418", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033304", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033304", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR059041", "url": "https://www.ebi.ac.uk/interpro/entry/IPR059041", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR060480", "url": "https://www.ebi.ac.uk/interpro/entry/IPR060480", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR060647", "url": "https://www.ebi.ac.uk/interpro/entry/IPR060647", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:420418", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420418", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LIKYTWE", "url": "https://omabrowser.org/oma/group/LIKYTWE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A8F0", "url": "https://www.orthodb.org/?gene=A0A8V1A8F0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AB76", "url": "https://www.orthodb.org/?gene=A0A8V1AB76", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ADC0", "url": "https://www.orthodb.org/?gene=A0A8V1ADC0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46348", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46348", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46348:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46348:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF23277", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23277", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23316", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23316", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF28484", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF28484", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003640722", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003640722", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1A8F0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8F0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A8F0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8F0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AB76", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB76", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AB76-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB76-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ADC0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADC0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ADC0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADC0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAQRSPSSRSQDISHLLSSTFKDLYTGDVIGADIEANWLKSRGGDDAYHEAFTEELQKLVVEYNHRLTEADAVEENIIQAQVRAKAEEERALNVLKGDAGKDFHKMGLPPVASSFRWIVDNELLRKNHLTCPDDYITDKLPVTRAPKGKAEPGYVKETFSFKQRVSSDSRDQMSAHLQKISAHLPSVSLSTLILPSTPDSYHRTKRTSKKSSASQKADWKGSKCKAEREECAYLAKLEKRQNFLKNPRFFPPNAPHGGKSLVMSQGQVEQIISNTSAECNTGDISFVPVFLAKPPTVFFSDYEVGRVYEITVELQNITSTCHRVGVIPPSTSVFSIGPGKFPGKGGMIAPGMTCQYTVQFVPESLADYTDYIWVQTPVSEPLLIPIQAKRAPPVLTLPRIIDCGFCLVGGIKVTVILCRNVGFSTGKFCIMPQEAWPPPNFRAVATLGSVIQDPFGIYPAVFELAPGQSTRVKVVFFPSLPEVSQQTYTIVCDNCQVNDVTVTGVGQLIALELLHVTGGESSSEPDEVTDVTAQHLIRFDPQNPHTTTQKILVIRNATHVELPFYWQIIKPNLQPIVPGETAHFVTPEYNRETESVFSLSPKQGVLLPHADHDFTLTYTPQELKIYHSVIQLVLRDIPESPSLVKGRILQNIPEYTAEDVIALDIEVKGSTEPFQLLLEPYAVIIPGENFLGVKVRRTFKMWNNSKSPIKYTWENITDCTIMEVEPLTGVIDRNEHCEFELMITGIRPGCVSHNLQCQIKHSAEPVVLHVEAAFKGPLLHISIPSLRLGLIKPGETVVGTFEIQNLCQLPARWRMQESQACLAERNEEVSPFTIQPPAEEIPPLGSCSVSVQYMSLLCQRLHTVLELEVENGERSYLPVSVEVQTPQACLISSHLVLTEMYTGVPVKATSKLFNQTRLPAKYSWGNLIGSQAAFCSATVTPASGILAPNEEKEFCIELTANITGELKGVALSCSIEDMIEPLFLSISGEVKGLHVTYSVPCEGGDASDERKMLQSPRDLLLDFGSEVALKDIVKRQLILTNHTAISAPFKLEAVYFTGSSPTPEQSVSLSSDYLVKRRGPITKHAAKRAQSEFAAAMLSHGKGVAFHVQPSSGTLQAFQQLIIEITAYNNMWGEYSDDLVCKVGDLQPTLIPMQMTVKGCPIFLQMTGPQTQRPIIRFGTHVSGGCPVFRNVQLNNPTAFDIRLDWETYNQEEGDKKLVDLLMLFEDPFPPKDMAKNETASTGSNSEIVLGLDQPPVPCGSIHPSLQTTDESSNTECEEEGIITQEPTRQKIVSVLLRPHEGVPADSPYSITPRQIVVPGGGSSSVCISFTPHVLPEPVAEVRCDGFVLGFMSLDDELAKTVPDKVHRRDGYDTAPLRIDMRASVRQALLKVDTDHDGGMVFYSVASDLLPDQPLLGVLSDSVLTQSLKLTNCTKVPLYFSLLLSAPFSLTSTDLKKSTNTFHSETEETEQEPQLVLYPQQNMLVKVSFHITLKLLMYQHLPDTQMLPGFQVLQGESGERKLKFSQNLIIEYSNHSTQLVPVTAYLTVPVLELSCNMVDFKTCLVAQTKTEHVFLCNRSSCRIYWTALLDQQERHSDLEVFSVSPANGILEAREGEQPTKDMLQITFTARSDTEYETILTVTGMLGEKPCKLQIRGQGTYDEKYEDMY", "length": 1668, "header": "tr|A0A8V1ADC0-1|A0A8V1ADC0_CHICK Isoform 1 of DLEC1 cilia and flagella associated protein OS=Gallus gallus OX=9031 GN=DLEC1 PE=4 SV=1 CANONICAL=A0A8V1ADC0-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A8F0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADC0/entry#A0A8V1A8F0-1", "sequence": { "sequence": "MAQRSPSSRSQDISHLLSSTFKDLYTGDVIGADIEANWLKSRGGDDAYHEAFTEELQKLVVEYNHRLTEADAVEENIIQAQVRAKAEEERALNVLKGDAGKDFHKMGLPPVASSFRWIVDNELLRKNHLTCPDDYITDKLPVTRAPKGKAEPGYVKETFSFKQRVSSDSRDQMSAHLQKISAHLPSVSLSTLILPSTPDSYHRTKRTSKKSSASQKADWKGSKCKAEREECAYLAKLEKRQNFLKNPRFFPPNAPHGGKSLVMSQGQVEQIISNTSAECNTGDISFVPVFLAKPPTVFFSDYEVGRVYEITVELQNITSTCHRVGVIPPSTSVFSIGPGKFPGKGGMIAPGMTCQYTVQFVPESLADYTDYIWVQTPVSEPLLIPIQAKRAPPVLTLPRIIDCGFCLVGGIKVTVILCRNVGFSTGKFCIMPQEAWPPPNFRAVATLGSVIQDPFGIYPAVFELAPGQSTRVKVVFFPSLPEVSQQTYTIVCDNCQVNDVTVTGVGQLIALELLHVTGGESSSEPDEVTDVTAQHLIRFDPQNPHTTTQKILVIRNATHVELPFYWQIIKPNLQPIVPGETAHFVTPEYNRETESVFSLSPKQGVLLPHADHDFTLTYTPQELKIYHSVIQLVLRDIPESPSLVKGRILQNIPEYTAEDVIALDIEVKGSTEPFQLLLEPYAVIIPGENFLGVKVRRTFKMWNNSKSPIKYTWENITDCTIMEVEPLTGVIDRNEHCEFELMITGIRPGCVSHNLQCQIKHSAEPVVLHVEAAFKGPLLHISIPSLRLGLIKPGETVVGTFEIQNLCQLPARWRMQESQACLAERNEEVSPFTIQPPAEEIPPLGSCSVSVQYMSLLCQRLHTVLELEVENGERSYLPVSVEVQTPQACLISSHLVLTEMYTGVPVKATSKLFNQTRLPAKYSWGNLIGSQAAFCSATVTPASGILAPNEEKEFCIELTANITGELKGVALSCSIEDMIEPLFLSISGEVKGLHVTYSVPCEGGDASDERKMLQSPRDLLLDFGSEVALKDIVKRQLILTNHTAISAPFKLEAVYFTGSSPTPEQSVSLSSDYLVKRRGPITKHAAKRAQSEFAAAMLSHGKGVAFHVQPSSGTLQAFQQLIIEITAYNNMWGEYSDDLVCKVGDLQPTLIPMQMTVKGCPIFLQMTGPQTQRPIIRFGTHVSGGCPVFRNVQLNNPTAFDIRLDWETYNQEEGDKKLVDLLMLFEDPFPPKDMAKNETASTGSNSEIVLGLDQPPVPCGSIHPSLQTTDESSNTECEEEGIITQEPTRQKIVSVLLRPHEGVPADSPYSITPRQIVVPGGGSSSVCISFTPHVLPEPVAEVRCDGFVLGFMSLDDELAKTVPDKVHRRDGYDTAPLRIDMRASVRQALLKVDTDHDGGMVFYSVASDLLPDQPLLGVLSDSVLTQSLKLTNCTKVPLYFSLLLSAPFSLTSTDLKKSTNTFHSETEETEQEPQLVLYPQQNMLVKVSFHITLKLLMYQHLPDTQMLPGFQVLQGESGERKLKFSQNLIIEYSNHSTQLVPVTAYLTVPVLELSCNMVDFKTCLVAQTKTEHVFLCNRSSCRIYWTALLDQQERHSDLEVFSVSPANGILEAREGEQPTKDMLQITFTARYS", "length": 1632, "header": "tr|A0A8V1A8F0-1|A0A8V1ADC0_CHICK Computationally mapped isoform of DLEC1 cilia and flagella associated protein OS=Gallus gallus OX=9031 GN=DLEC1 PE=4 SV=1 CANONICAL=A0A8V1ADC0-1" }, "locus": { "chromosome": "2", "start_pos": 4721252, "end_pos": 4686946, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010064332.1", "url": "https://www.ensembl.org/id/ENSGALT00010064332.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039500.1", "url": "https://www.ensembl.org/id/ENSGALP00010039500.1" } ] } }, { "isoform_ac": "A0A8V1AB76-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADC0/entry#A0A8V1AB76-1", "sequence": { "sequence": "MAQRSPSSRSQDISHLLSSTFKDLYTGDVIGADIEANWLKSRGGDDAYHEAFTEELQKLVVEYNHRLTEADAVEENIIQAQVRAKAEEERALNVLKGDAGKDFHKMGLPPGKAEPGYVKETFSFKQRVSSDSRDQMSAHLQKISAHLPSVSLSTLILPSTPDSYHRTKRTSKKSSASQKADWKGSKCKAEREECAYLAKLEKRQNFLKNPRFFPPNAPHGGKSLVMSQGQVEQIISNTSAECNTGDISFVPVFLAKPPTVFFSDYEVGRVYEITVELQNITSTCHRVGVIPPSTSVFSIGPGKFPGKGGMIAPGMTCQYTVQFVPESLADYTDYIWVQTPVSEPLLIPIQAKRAPPVLTLPRIIDCGFCLVGGIKVTVILCRNVGFSTGKFCIMPQEAWPPPNFRAVATLGSVIQDPFGIYPAVFELAPGQSTRVKVVFFPSLPEVSQQTYTIVCDNCQVNDVTVTGVGQLIALELLHVTGGESSSEPDEVTDVTAQHLIRFDPQNPHTTTQKILVIRNATHVELPFYWQIIKPNLQPIVPGETAHFVTPEYNRETESVFSLSPKQGVLLPHADHDFTLTYTPQELKIYHSVIQLVLRDIPESPSLVKGRILQNIPEYTAEDVIALDIEVKGSTEPFQLLLEPYAVIIPGENFLGVKVRRTFKMWNNSKSPIKYTWENITDCTIMEVEPLTGVIDRNEHCEFELMITGIRPGCVSHNLQCQIKHSAEPVVLHVEAAFKGPLLHISIPSLRLGLIKPGETVVGTFEIQNLCQLPARWRMQESQACLAERNEEVSPFTIQPPAEEIPPLGSCSVSVQYMSLLCQRLHTVLELEVENGERSYLPVSVEVQTPQACLISSHLVLTEMYTGVPVKATSKLFNQTRLPAKYSWGNLIGSQAAFCSATVTPASGILAPNEEKEFCIELTANITGELKGVALSCSIEDMIEPLFLSISGEVKGLHVTYSVPCEGGDASDERKMLQSPRDLLLDFGSEVALKDIVKRQLILTNHTAISAPFKLEAVYFTGSSPTPEQSVSLSSDYLVKRRGPITKHAAKRAQSEFAAAMLSHGKGVAFHVQPSSGTLQAFQQLIIEITAYNNMWGEYSDDLVCKVGDLQPTLIPMQMTVKGCPIFLQMTGPQTQRPIIRFGTHVSGGCPVFRNVQLNNPTAFDIRLDWETYNQEEGDKKLVDLLMLFEDPFPPKDMAKNETASTGSNSEIVLGLDQPPVPCGSIHPSLQTTDESSNTECEEEGIITQEPTRQKIVSVLLRPHEGVPADSPYSITPRQIVVPGGGSSSVCISFTPHVLPEPVAEVRCDGFVLGFMSLDDELAKTVPDKVHRRDGYDTAPLRIDMRASVRQALLKVDTDHDGGMVFYSVASDLLPDQPLLGVLSDSVLTQSLKLTNCTKVPLYFSLLLSAPFSLTSTDLKKSTNTFHSETEETEQEPQLVLYPQQNMLVKVSFHITLKLLMYQHLPDTQMLPGFQVLQGESGERKLKFSQNLIIEYSNHSTQLVPVTAYLTVPVLELSCNMVDFKTCLVAQTKTEHVFLCNRSSCRIYWTALLDQQERHSDLEVFSVSPANGILEAREGEQPTKDMLQITFTARSDTEYETILTVTGMLGEKPCKLQIRGQGTYDEKYEDMY", "length": 1631, "header": "tr|A0A8V1AB76-1|A0A8V1AB76_CHICK Computationally mapped isoform of DLEC1 cilia and flagella associated protein OS=Gallus gallus OX=9031 GN=DLEC1 PE=4 SV=1 CANONICAL=A0A8V1ADC0-1" }, "locus": { "chromosome": "2", "start_pos": 4723127, "end_pos": 4686946, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010064354.1", "url": "https://www.ensembl.org/id/ENSGALT00010064354.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039504.1", "url": "https://www.ensembl.org/id/ENSGALP00010039504.1" } ] } }, { "isoform_ac": "A0A8V1ADC0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADC0/entry#A0A8V1ADC0-1", "sequence": { "sequence": "MAQRSPSSRSQDISHLLSSTFKDLYTGDVIGADIEANWLKSRGGDDAYHEAFTEELQKLVVEYNHRLTEADAVEENIIQAQVRAKAEEERALNVLKGDAGKDFHKMGLPPVASSFRWIVDNELLRKNHLTCPDDYITDKLPVTRAPKGKAEPGYVKETFSFKQRVSSDSRDQMSAHLQKISAHLPSVSLSTLILPSTPDSYHRTKRTSKKSSASQKADWKGSKCKAEREECAYLAKLEKRQNFLKNPRFFPPNAPHGGKSLVMSQGQVEQIISNTSAECNTGDISFVPVFLAKPPTVFFSDYEVGRVYEITVELQNITSTCHRVGVIPPSTSVFSIGPGKFPGKGGMIAPGMTCQYTVQFVPESLADYTDYIWVQTPVSEPLLIPIQAKRAPPVLTLPRIIDCGFCLVGGIKVTVILCRNVGFSTGKFCIMPQEAWPPPNFRAVATLGSVIQDPFGIYPAVFELAPGQSTRVKVVFFPSLPEVSQQTYTIVCDNCQVNDVTVTGVGQLIALELLHVTGGESSSEPDEVTDVTAQHLIRFDPQNPHTTTQKILVIRNATHVELPFYWQIIKPNLQPIVPGETAHFVTPEYNRETESVFSLSPKQGVLLPHADHDFTLTYTPQELKIYHSVIQLVLRDIPESPSLVKGRILQNIPEYTAEDVIALDIEVKGSTEPFQLLLEPYAVIIPGENFLGVKVRRTFKMWNNSKSPIKYTWENITDCTIMEVEPLTGVIDRNEHCEFELMITGIRPGCVSHNLQCQIKHSAEPVVLHVEAAFKGPLLHISIPSLRLGLIKPGETVVGTFEIQNLCQLPARWRMQESQACLAERNEEVSPFTIQPPAEEIPPLGSCSVSVQYMSLLCQRLHTVLELEVENGERSYLPVSVEVQTPQACLISSHLVLTEMYTGVPVKATSKLFNQTRLPAKYSWGNLIGSQAAFCSATVTPASGILAPNEEKEFCIELTANITGELKGVALSCSIEDMIEPLFLSISGEVKGLHVTYSVPCEGGDASDERKMLQSPRDLLLDFGSEVALKDIVKRQLILTNHTAISAPFKLEAVYFTGSSPTPEQSVSLSSDYLVKRRGPITKHAAKRAQSEFAAAMLSHGKGVAFHVQPSSGTLQAFQQLIIEITAYNNMWGEYSDDLVCKVGDLQPTLIPMQMTVKGCPIFLQMTGPQTQRPIIRFGTHVSGGCPVFRNVQLNNPTAFDIRLDWETYNQEEGDKKLVDLLMLFEDPFPPKDMAKNETASTGSNSEIVLGLDQPPVPCGSIHPSLQTTDESSNTECEEEGIITQEPTRQKIVSVLLRPHEGVPADSPYSITPRQIVVPGGGSSSVCISFTPHVLPEPVAEVRCDGFVLGFMSLDDELAKTVPDKVHRRDGYDTAPLRIDMRASVRQALLKVDTDHDGGMVFYSVASDLLPDQPLLGVLSDSVLTQSLKLTNCTKVPLYFSLLLSAPFSLTSTDLKKSTNTFHSETEETEQEPQLVLYPQQNMLVKVSFHITLKLLMYQHLPDTQMLPGFQVLQGESGERKLKFSQNLIIEYSNHSTQLVPVTAYLTVPVLELSCNMVDFKTCLVAQTKTEHVFLCNRSSCRIYWTALLDQQERHSDLEVFSVSPANGILEAREGEQPTKDMLQITFTARSDTEYETILTVTGMLGEKPCKLQIRGQGTYDEKYEDMY", "length": 1668, "header": "tr|A0A8V1ADC0-1|A0A8V1ADC0_CHICK Isoform 1 of DLEC1 cilia and flagella associated protein OS=Gallus gallus OX=9031 GN=DLEC1 PE=4 SV=1 CANONICAL=A0A8V1ADC0-1" }, "locus": { "chromosome": "2", "start_pos": 4723127, "end_pos": 4686946, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010064343.1", "url": "https://www.ensembl.org/id/ENSGALT00010064343.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039502.1", "url": "https://www.ensembl.org/id/ENSGALP00010039502.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1062, "start_aa": "Thr", "end_pos": 1062, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1062", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 940, "start_aa": "Thr", "end_pos": 940, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr940", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:420418", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420418", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8N7UUL3-1", "protein_name": "Deleted in lung and esophageal cancer protein 1 isoform X1", "gene_name": "dlec1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MADETEPKALTLKSSEPSINRHTPASKTTQDISHLLASIFNDLYSTEVIGKDTVSNLSKSRRRGNSYHEKYVEELQQVHSEYNRRIQNADMLETHIIQARLQAAAKEEHDRNKILEEVGEAYQQLGLPPVKSAFKWCVDSGLLRSNSLICPLDYTTVHNPVVKSPKARSSPGFAKPTFSYNMHISTELQDDGYTPLPPHAHSAHSLLEYSEETITLSSSPESSSINDTELGLVAKASWMEKTSAKSHAEDRASLKKHKDRHKFLHNPRFLLPNTQHGGKSLIIPGKKKLENVGKSRKNNGRERSLEGHAPIFTANPPVIFFSDYRVGQVYETSVELKNMTASSRHIRMIPPTSPHFSVGLGRFPGEGGIVAPGMSCQYMVRFAPDSLADYEDALVVETQMLYPLIIPIEACRSPPILTLPAVMDCGFCLVGGVKFMEVLCRNEGLSAGTFCVMPKKQWPASSLRSAVKSTFTEQPPFAISPSIFGLHPGQATVIEVVFFPTTPELSTQDFTIVCDNCQVKDITLQGTGQLITVELLSVSGGEDQPEFAELCDITADHYVRFNTTNPHSTLQKTLVVKNNTHLELPYHWQIMKPSLQCLLPGETPDPSSIQHLLDTDSAFSISPVIGILNPAQEHEFLLTYAPKDIKDYHSVCHLVIMDVPSPPKVCDDGTCPDTALHANNVTILEVEVKGSTEPYKILLEPYAVLIPGETYIHNTICKRFKMWNHSKSVIHFEWERVIDSHVIEVEPSSGVIEMNECFDMELYLTGRSPGHFTSTLQCHILHHPKTIGLAIEATFKGPHCSLNVPSLDFGLLQMGNERILTIEVTNNSLLDAHWSLEVLSQTQKLIDGQVHINPNKGVLAALESCSVDVAFRAMHCQVFESVLQLSVLNGTGCHVSIHAVVQSPQVCLLNCELLFADLYVGVSQTGSVTLFNQTLLPAHFTWGRLQGSQAHLCSAVFSPSAGSLGPNAKTEVSVSFTAHTVEDLTEVNGVCEVKGMENPLVLGIFSKAKPLRVSYSLLCNGINSGDGDHQPILLDFTEHEPAVIGKSVKRQLLITNNTAITAPFTVDTEYFTGDCPSQSEGNSERSSAPFHSIQAKKIQQKAYDEFVSRLLSHGRGATFYVEPKSGMLGPFESQTINITTFTNMWGDYQDNLICKVGDLNPTHIHMKMSVRGCPVYFQMIGPQPDNQNQGPVIRFGSHVSGGDTVSRSLRLINTSPYDIRMDWVTYNLEAGDGKLIDLLLACGEPFPLKDADGNEVVGGLDSSVMFPSTWDDSHTPSREGTSSTFMTQSDDFVENGEECDGEDGSGASESLAPVKKLFSVFLKPHEGTLSDYPYCITPQQTVVPAGGSSTIHLSFTPLILSCSTNQRCLGYALGFMSLDSKLALVTPGKVERVRGYELQPLRLDMQANVKPAILSVQMAEDTEVLEFSAAASDTLDGASQTQESRITRTFRLKNDTDMALSFKLSTNPPFSVLLPRQSLKLISSSPAYRHTQGLSGPGDEMRLFLLQPKNIIQVKVAFHNSASLLACVNGACEESDSQLSASLLCSDDGGKTLQFQENLTIQYSNNSIQTVSLYARLALPTLHLSSATVDFGTCYVGQTTVKEIYLHNRGGSCSYWTTLTDGNEVFRVSPDSGLLKPLGDPASCRQLLQISFTPREQKEFQTIFTVQGLLGETPLVLKVSGRGSFDESFVSPITDSSQNNTE", "length": 1702 }, "evidence": [ { "id": "A0A8V1ADC0", "url": "https://omabrowser.org/oma/group/A0A8V1ADC0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q68FQ8-1", "protein_name": "Deleted in lung and esophageal cancer protein 1 homolog", "gene_name": "Dlec1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEPESKKELQSPASSFVMSSETMWESTPRQPESTSLSWSPRKSLRSLTVFTDYCQFGYPTRSLRAGFQELPPLPEPQTLRLRPASLRTQDISHLLARVFRNLYTAQVIGDDLSDSLIKARGSEDARHEEFLDQLQQARAIYKKRLDDVAMLEKHITQARARDIAETEHATKQGRLHVVEAPVKLPPVKTVFRWCIDNELMQKHHLISTEDYYNDPLPFCPAPKRSPTPMYSKMTFSCEKRFTHKSDLERKAEEHCRKLVEFDDLEYTTDSLRSVSKTKGKTKVTIKKASTPANKKWMEHLQVPQRALDRRLLARMQNRNHYLKNPRFFPPNTPHGGKSLIVPSRKPERRGSLSAKPEWRCVCSSRRIPGNVSFRVNLDLVYGGPQTLASQGSVPEESGVLGSTSGMAFDPQGPRVRLFSAVRSRGVDPWEPVWASSGHPKWGGAGAGAYSHVTLAWYVDYLFLLL", "length": 465 }, "evidence": [ { "id": "A0A8V1ADC0", "url": "https://omabrowser.org/oma/group/A0A8V1ADC0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8BLA1-1", "protein_name": "Deleted in lung and esophageal cancer protein 1 homolog", "gene_name": "Dlec1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDSESKEEQQCTASSAVMSSLETQFLSVPHQLESASLSWSIRKSLHSSTVLMDDCHFGFPTRSLRAGFHALPPLPEPQTLRLRPASLRTQEISHLLARVFRNLYTAQVIGDDLSDSLIKARGSEDARHEEFLDQLQQARAIYKQRLDEAAMLERHIMQARARDIAETEHTTKQSRLQVVETPVKLPPVKTAFRWCLDSKLMRKHHLISTEDYYTDPVPFCPAPKDKSTLGCSKLTFSCEQRFLRKSELDREAEEHCRQLTECDDFEYTVDSLGSISKAKERTTDSVKKTSRPKNKKWMEHLQVPQRALDRRLLASMENRNHFLKNPRFFPPNTPHGGKSLIVPLSKPERRASLNAEPEWSCTDAPVFLAKPSVGFFTDYEIGPVYEMVIALQNTTSTSRFLRVLPPSSPYFALGLGMFPGKGGIVAPGMTCQYIVQFIPDCLGDFDDFILVETQSPHTLVIPLQARRPPPVLTLSPVLDCGHCLIGGVKITKFICKNVGFSVGKFCIMPQKSWPPPSFRAVATTGFVEQPPFGVMPSVFELAPGYAILLEVLFLPTGLGQAEETFIIVCDNCQIKEVVVVGTGQLVALDLIHISGGKNEPDPGELKDLTAQYFIRFEPENVQSTPKKQLIIRNAT", "length": 635 }, "evidence": [ { "id": "A0A8V1ADC0", "url": "https://omabrowser.org/oma/group/A0A8V1ADC0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9Y238-1", "protein_name": "Deleted in lung and esophageal cancer protein 1", "gene_name": "DLEC1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METRSSKTRRSLASRTNECQGTMWAPTSPPAGSSSPSQPTWKSSLYSSLAYSEAFHYSFAARPRRLTQLALAQRPEPQLLRLRPSSLRTQDISHLLTGVFRNLYSAEVIGDEVSASLIKARGSENERHEEFVDQLQQIRELYKQRLDEFEMLERHITQAQARAIAENERVMSQAGVQDLESLVRLPPVKSVSRWCIDSELLRKHHLISPEDYYTDTVPFHSAPKGISLPGCSKLTFSCEKRSVQKKELNKKLEDSCRKKLAEFEDELDHTVDSLTWNLTPKAKERTREPLKKASQPRNKNWMNHLRVPQRELDRLLLARMESRNHFLKNPRFFPPNTRYGGKSLVFPPKKPAPIGEFQSTEPEQSCADTPVFLAKPPIGFFTDYEIGPVYEMVIALQNTTTTSRYLRVLPPSTPYFALGLGMFPGKGGMVAPGMTCQYIVQFFPDCLGDFDDFILVETQSAHTLLIPLQARRPPPVLTLSPVLDCGYCLIGGVKMTRFICKNVGFSVGRFCIMPKTSWPPLSFKAIATVGFVEQPPFGILPSVFELAPGHAILVEVLFSPKSLGKAEQTFIIMCDNCQIKELVTIGIGQLIALDLIYISGEKSQPDPGELTDLTAQHFIRFEPENLRSTARKQLIIRNATHVELAFYWQIMKPNLQPLMPGETFSMDSIKCYPDKETAFSIMPRKGVLSPHTDHEFILSFSPHELRDFHSVLQMVLEEVPEPVSSEAESLGHSSYSVDDVIVLEIEVKGSVEPFQVLLEPYALIIPGENYIGINVKKAFKMWNNSKSPIRYLWGKISDCHIIEVEPGTGVIEPSEVGDFELNFTGGVPGPTSQDLLCEIEDSPSPVVLHIEAVFKGPALIINVSALQFGLLRLGQKATNSIQIRNVSQLPATWRMKESPVSLQERPEDVSPFDIEPSSGQLHSLGECRVDITLEALHCQHLETVLELEVENGAWSYLPVYAEVQKPHVYLQSSQVEVRNLYLGVPTKTTITLINGTLLPTQFHWGKLLGHQAEFCMVTVSPKHGLLGPSEECQLKLELTAHTQEELTHLALPCHVSGMKKPLVLGISGKPQGLQVAITISKESSDCSTEQWPGHPKELRLDFGSAVPLRTRVTRQLILTNRSPIRTRFSLKFEYFGSPQNSLSKKTSLPNMPPALLKTVRMQEHLAKREQLDFMESMLSHGKGAAFFPHFSQGMLGPYQQLCIDITGCANMWGEYWDNLICTVGDLLPEVIPVHMAAVGCPISSLRTTSYTIDQAQKEPAMRFGTQVSGGDTVTRTLRLNNSSPCDIRLDWETYVPEDKEDRLVELLVFYGPPFPLRDQAGNELVCPDTPEGGCLLWSPGPSSSSEFSHETDSSVEGSSSASNRVAQKLISVILQAHEGVPSGHLYCISPKQVVVPAGGSSTIYISFTPMVLSPEILHKVECTGYALGFMSLDSKVEREIPGKRHRLQDFAVGPLKLDLHSYVRPAQLSVELDYGGSMEFQCQASDLIPEQPCSGVLSELVTTHHLKLTNTTEIPHYFRLMVSRPFSVSQDGASQDHRAPGPGQKQECEEETASADKQLVLQAQENMLVNVSFSLSLELLSYQKLPADQTLPGVDIQQSASGEREMVFTQNLLLEYTNQTTQVVPLRAVVAVPELQLSTSWVDFGTCFVSQQRVREVYLMNLSGCRSYWTMLMGQQEPAKAAVAFRVSPNSGLLEARSANAPPTSIALQVFFTARSSELYESTMVVEGVLGEKSCTLRLRGQGSYDERYMLPHQP", "length": 1755 }, "evidence": [ { "id": "A0A8V1ADC0", "url": "https://omabrowser.org/oma/group/A0A8V1ADC0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "negative regulation of cell population proliferation", "id": "GO:0008285", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008285", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADC0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADC0" } ], "pmid": "" }, { "name": "defense response to tumor cell", "id": "GO:0002357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002357", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADC0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADC0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADC0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADC0" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADC0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADC0" } ], "pmid": "" }, { "name": "cilium", "id": "GO:0005929", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005929", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADC0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADC0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "tubulin binding", "id": "GO:0015631", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015631", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADC0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADC0" } ], "pmid": "" }, { "name": "beta-tubulin binding", "id": "GO:0048487", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048487", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADC0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADC0" } ], "pmid": "" }, { "name": "alpha-tubulin binding", "id": "GO:0043014", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043014", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADC0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADC0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1041, "end_pos": 1043, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1237, "end_pos": 1239, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1432, "end_pos": 1434, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1534, "end_pos": 1536, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1577, "end_pos": 1579, "annotation": "n_glycosylation_sequon" }, { "start_pos": 274, "end_pos": 276, "annotation": "n_glycosylation_sequon" }, { "start_pos": 316, "end_pos": 318, "annotation": "n_glycosylation_sequon" }, { "start_pos": 556, "end_pos": 558, "annotation": "n_glycosylation_sequon" }, { "start_pos": 703, "end_pos": 705, "annotation": "n_glycosylation_sequon" }, { "start_pos": 715, "end_pos": 717, "annotation": "n_glycosylation_sequon" }, { "start_pos": 914, "end_pos": 916, "annotation": "n_glycosylation_sequon" }, { "start_pos": 961, "end_pos": 963, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1ADC0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADC0" }, { "id": "PF28484", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF28484" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DLEC1 helical", "eco_id": "ECO_0000259", "start_pos": 62, "end_pos": 139, "start_aa": "Glu", "end_aa": "Lys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1ADC0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADC0" }, { "id": "PF23316", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23316" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DLEC1 sixth Ig-like", "eco_id": "ECO_0000259", "start_pos": 886, "end_pos": 990, "start_aa": "Pro", "end_aa": "Val", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1ADC0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADC0" }, { "id": "PF23277", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23277" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Deleted in lung and esophageal cancer protein 1 Ig-like", "eco_id": "ECO_0000259", "start_pos": 290, "end_pos": 376, "start_aa": "Phe", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 940, 1062 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1041, "end_pos": 1043 }, { "start_pos": 1237, "end_pos": 1239 }, { "start_pos": 1432, "end_pos": 1434 }, { "start_pos": 1534, "end_pos": 1536 }, { "start_pos": 1577, "end_pos": 1579 }, { "start_pos": 274, "end_pos": 276 }, { "start_pos": 316, "end_pos": 318 }, { "start_pos": 556, "end_pos": 558 }, { "start_pos": 703, "end_pos": 705 }, { "start_pos": 715, "end_pos": 717 }, { "start_pos": 914, "end_pos": 916 }, { "start_pos": 961, "end_pos": 963 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1ADQ5-1", "uniprot_ac": "A0A8V1ADQ5", "uniprot_id": "A0A8V1ADQ5_CHICK", "mass": { "chemical_mass": 31292.0, "monoisotopic_mass": 31292.0 }, "refseq": {}, "gene_names": [ { "name": "S100A14", "type": "recommended", "evidence": [ { "id": "A0A8V1ADQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADQ5" } ] } ], "protein_names": [ { "name": "S100 calcium binding protein A14", "type": "synonym", "evidence": [ { "id": "A0A8V1ADQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADQ5/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADQ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADQ5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "S100A14", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADQ5", "locus": {} } ], "crossref": [ { "id": "A0A8V1ADQ5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1ADQ5", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd05022", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05022", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR011992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013787", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013787", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018247", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018247", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A8M3", "url": "https://www.orthodb.org/?gene=A0A8V1A8M3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ADQ5", "url": "https://www.orthodb.org/?gene=A0A8V1ADQ5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AGA8", "url": "https://www.orthodb.org/?gene=A0A8V1AGA8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11639", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11639", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11639:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11639:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01023", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01023", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1A8M3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8M3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A8M3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8M3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ADQ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADQ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ADQ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADQ5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGA8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGA8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGA8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGA8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAPGAHGMEPGAWCMVPGAQSMVSTAWCMVPGAQCTVPSAWYLVHGAWYPVPKAWFPLHGAWYLALSAWYLVHGASCSVHGASCSVHGAWYPVPIPTQHCVAMPDGKRSVWPRRRRFPAPRWPGARLPNEAPCTTPCRELPLTPPRYKTPQQRNARTAGTALAAAPQDPPEQRDCRPRRSSMGQCNCRKKRKDNQELTDVERAIETVINQFHCYAVKGQKEYLTPNEMRELVVQKLPHLGKCVGPLDEKIECMGDPDEAKLEFGEYWDMMGDAAKGCRRK", "length": 280, "header": "tr|A0A8V1ADQ5-1|A0A8V1ADQ5_CHICK Isoform 1 of S100 calcium binding protein A14 OS=Gallus gallus OX=9031 GN=S100A14 PE=4 SV=1 CANONICAL=A0A8V1ADQ5-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A8M3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADQ5/entry#A0A8V1A8M3-1", "sequence": { "sequence": "MFPLRGAVCAWSTQAAAVWGGDGKLLPGGVCNGKPNGKPCTGVRDHALLSTAVRPRGGLQLSGDTLLPAAPMAAAELTPVEMAIETIVSVFVSHAGKEGRMGTLTATAFQELLRLQLPNLMKDVPSLEEQMRALDVSTEQELTFEEFWKLMAPQDPPEQRDCRPRRSSMGQCNCRKKRKDNQELTDVERAIETVINQFHCYAVKGQKEYLTPNEMRELVVQKLPHLGKCVGPLDEKIECMGDPDEAKLEFGEYWDMMGDAAKGCRRK", "length": 267, "header": "tr|A0A8V1A8M3-1|A0A8V1ADQ5_CHICK Computationally mapped isoform of S100 calcium binding protein A14 OS=Gallus gallus OX=9031 GN=S100A14 PE=4 SV=1 CANONICAL=A0A8V1ADQ5-1" }, "locus": { "chromosome": "25", "start_pos": 1735092, "end_pos": 1730959, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068863.1", "url": "https://www.ensembl.org/id/ENSGALT00010068863.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042305.1", "url": "https://www.ensembl.org/id/ENSGALP00010042305.1" } ] } }, { "isoform_ac": "A0A8V1ADQ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADQ5/entry#A0A8V1ADQ5-1", "sequence": { "sequence": "MAPGAHGMEPGAWCMVPGAQSMVSTAWCMVPGAQCTVPSAWYLVHGAWYPVPKAWFPLHGAWYLALSAWYLVHGASCSVHGASCSVHGAWYPVPIPTQHCVAMPDGKRSVWPRRRRFPAPRWPGARLPNEAPCTTPCRELPLTPPRYKTPQQRNARTAGTALAAAPQDPPEQRDCRPRRSSMGQCNCRKKRKDNQELTDVERAIETVINQFHCYAVKGQKEYLTPNEMRELVVQKLPHLGKCVGPLDEKIECMGDPDEAKLEFGEYWDMMGDAAKGCRRK", "length": 280, "header": "tr|A0A8V1ADQ5-1|A0A8V1ADQ5_CHICK Isoform 1 of S100 calcium binding protein A14 OS=Gallus gallus OX=9031 GN=S100A14 PE=4 SV=1 CANONICAL=A0A8V1ADQ5-1" }, "locus": { "chromosome": "25", "start_pos": 1733361, "end_pos": 1730959, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068860.1", "url": "https://www.ensembl.org/id/ENSGALT00010068860.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042302.1", "url": "https://www.ensembl.org/id/ENSGALP00010042302.1" } ] } }, { "isoform_ac": "A0A8V1AGA8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADQ5/entry#A0A8V1AGA8-1", "sequence": { "sequence": "MAAAELTPVEMAIETIVSVFVSHAGKEGRMGTLTATAFQELLRLQLPNLMKDNQELTDVERAIETVINQFHCYAVKGQKEYLTPNEMRELVVQKLPHLGKCVGPLDEKIECMGDPDEAKLEFGEYWDMMGDAAKGCRRK", "length": 139, "header": "tr|A0A8V1AGA8-1|A0A8V1ADQ5_CHICK Computationally mapped isoform of S100 calcium binding protein A14 OS=Gallus gallus OX=9031 GN=S100A14 PE=4 SV=1 CANONICAL=A0A8V1ADQ5-1" }, "locus": { "chromosome": "25", "start_pos": 1734619, "end_pos": 1730959, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068862.1", "url": "https://www.ensembl.org/id/ENSGALT00010068862.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042304.1", "url": "https://www.ensembl.org/id/ENSGALP00010042304.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADQ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADQ5" } ], "pmid": "" }, { "name": "calcium-dependent protein binding", "id": "GO:0048306", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048306", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADQ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADQ5" } ], "pmid": "" }, { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADQ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADQ5" } ], "pmid": "" }, { "name": "chemokine receptor binding", "id": "GO:0042379", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042379", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADQ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADQ5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADQ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADQ5" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADQ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADQ5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "response to lipopolysaccharide", "id": "GO:0032496", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032496", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADQ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADQ5" } ], "pmid": "" }, { "name": "positive regulation of monocyte chemotaxis", "id": "GO:0090026", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090026", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADQ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADQ5" } ], "pmid": "" }, { "name": "toll-like receptor 4 signaling pathway", "id": "GO:0034142", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034142", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADQ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADQ5" } ], "pmid": "" }, { "name": "positive regulation of granulocyte chemotaxis", "id": "GO:0071624", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071624", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADQ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADQ5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1ADQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADQ5" }, { "id": "SM01394", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM01394" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "S100/CaBP-9k-type calcium binding subdomain", "eco_id": "ECO_0000259", "start_pos": 200, "end_pos": 241, "start_aa": "Val", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1ADJ5-1", "uniprot_ac": "A0A8V1ADJ5", "uniprot_id": "A0A8V1ADJ5_CHICK", "mass": { "chemical_mass": 75081.0, "monoisotopic_mass": 75081.0 }, "refseq": { "ac": "XP_015146669", "name": "FYN-binding protein 2 isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015146669" }, "gene_names": [ { "name": "FYB2", "type": "recommended", "evidence": [ { "id": "A0A8V1ADJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADJ5" } ] }, { "name": "FYB2", "type": "synonym", "evidence": [ { "id": "XP_015146669", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015146669" } ] } ], "protein_names": [ { "name": "FYN-binding protein 2", "type": "recommended", "evidence": [ { "id": "A0A8V1ADJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADJ5/entry#names_and_taxonomy" } ] }, { "name": "Activation-dependent, raft-recruited ADAP-like phosphoprotein", "type": "synonym", "evidence": [ { "id": "A0A8V1ADJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADJ5/entry#names_and_taxonomy" } ] }, { "name": "FYN-binding protein 2 isoform X3", "type": "synonym", "evidence": [ { "id": "XP_015146669", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015146669" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052539.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015146669.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015146669", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015146669" } ] }, { "annotation": "Adapter protein that plays a role in T-cell receptor (TCR)-mediated activation of signaling pathways. Required for T-cell activation and integrin-mediated T-cell adhesion in response to TCR stimulation.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A8M7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8M7#function" }, { "database": "UniProtKB", "id": "ARBA00060088", "url": "https://www.uniprot.org/uniprotkb/ARBA00060088#function" }, { "database": "UniProtKB", "id": "A0A8V1ADJ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADJ5#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADJ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADJ5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FYB2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADJ5", "locus": { "chromosome": "8", "start_pos": 25468565, "end_pos": 25512830, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010026628", "url": "https://www.ensembl.org/id/ENSGALG00010026628" } ] } } ], "crossref": [ { "id": "A0A8V1ADJ5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1ADJ5", "database": "AlphaFoldDB", "categories": [] }, { "id": "424668", "url": "https://www.ncbi.nlm.nih.gov/gene/424668", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR029294", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029294", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036028", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036028", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043443", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043443", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:424668", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424668", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1A8M7", "url": "https://www.orthodb.org/?gene=A0A8V1A8M7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ABG7", "url": "https://www.orthodb.org/?gene=A0A8V1ABG7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ADJ5", "url": "https://www.orthodb.org/?gene=A0A8V1ADJ5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16830", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16830", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16830:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16830:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14603", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14603", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015146669", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015146669", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1A8M7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8M7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A8M7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8M7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ABG7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABG7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ABG7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABG7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ADJ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADJ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ADJ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADJ5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPVQGSGAMDVEGVTDFRALRAKFQHDSSIATKPVQLCQKPSPRLGSGGSGVPRPMPNSKADVLVPGSHSAQRAKMGHTEPMEHNEEHKGNVSVKGLSSPKSSSPKQPVSYCTEQQASVQADPEDAPLLNSFHHALQMWQNTLSGGEKASTDLPARRAMNLYVQPSPGQRVLRAPATSNGSKVPPVGSHPEPARPAQGLTSAQATQGDEKGAGSSAATTLQPQCQKESKPPLCQPGAGTQLGNKPPKIRPLPSAASLGPAPRKPLRPPKVDLSSFRSTVPSVHRQNETTAEEEDYLIPESTQCEEQHNYEKTLMYLNQSEDTTTLRVIEVPKVEPQEHKKQKSFLFGESSPGRAIIEDEKEGKTSLEREKLEVKKPGGNEYIILSGQAREDDRGGMKVSHMRQDVTSTPQRLAKDRAKPLYYGAPKPTEDRPTSSPNHHQLLLTPDNVYDDVEGLQDRLSRASDASSPSASDIRSNYEETYEDVETGSDNPAKEEAEKQKRFGKLFKIEKLKLKNTRFKENLRLFSMSVPNLADVSQEDMVYDDAETEQKDPREKDDKHKTWMPKFLMAKEAKDRRKSSDDVERSIFKVKKSNAEKNKMEKEEKIFRETFLYDKEIRVINTATAACSIPSKRRADLPLTAGEQLDVIDVTEGSAVICRNSEGRYGYVLVEYLNFRQY", "length": 677, "header": "tr|A0A8V1ADJ5-1|A0A8V1ADJ5_CHICK Isoform 1 of FYN-binding protein 2 OS=Gallus gallus OX=9031 GN=FYB2 PE=4 SV=1 CANONICAL=A0A8V1ADJ5-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A8M7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADJ5/entry#A0A8V1A8M7-1", "sequence": { "sequence": "MPESREGVTDFRALRAKFQHDSSIATKPVQLCQKPSPRLGSGGSGVPRPMPNSKADVLVPGSHSAQRAKMGHTEPMEHNEEHKGNVSVKGLSSPKSSSPKQPVSYCTEQQASVQADPEDAPLLNSFHHALQMWQNTLSGGEKASTDLPARRAMNLYVQPSPGQRVLRAPATSNGSKVPPVGSHPEPARPAQGLTSAQATQGDEKGAGSSAATTLQPQCQKESKPPLCQPGAGTQLGNKPPKIRPLPSAASLGPAPRKPLRPPKVDLSSFRSTVPSVHRQNETTAEEEDYLIPESTQCEEQHNYEKTLMYLNQSEDTTTLRVIEVPKVEPQEHKKQKSFLFGESSPGRAIIEDEKEGKTSLEREKLEVKKPGGNEYIILSGQAREDDRGGMKVSHMRQDVTSTPQRLAKDRAKPLYYGAPKPTEDRPTSSPNHHQLLLTPDNVYDDVEGLQDRLRASDASSPSASDIRSNYEETYEDVETGSDNPAKEEAEKQKRFGKLFKIEKLKLKNTRFKENLRLFSMSVPNLADVSQEDMVYDDAETEQKDPREKDDKHKTWMPKFLMAKEAKDRRKSSDDVERSIFKVKKSNAEKNKMEKEEKIFRETFLYDKEIRVINTATAACSIPSKRRADLPLTAGEQLDVIDVTEGSAVICRNSEGRYGYVLVEYLNFRQY", "length": 670, "header": "tr|A0A8V1A8M7-1|A0A8V1ADJ5_CHICK Computationally mapped isoform of FYN-binding protein 2 OS=Gallus gallus OX=9031 GN=FYB2 PE=4 SV=1 CANONICAL=A0A8V1ADJ5-1" }, "locus": { "chromosome": "8", "start_pos": 25510989, "end_pos": 25468892, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010064663.1", "url": "https://www.ensembl.org/id/ENSGALT00010064663.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039581.1", "url": "https://www.ensembl.org/id/ENSGALP00010039581.1" } ] } }, { "isoform_ac": "A0A8V1ABG7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADJ5/entry#A0A8V1ABG7-1", "sequence": { "sequence": "MPNSKADVLVPGSHSAQRAKMGHTEPMEHNEEHKGNVSVKGLSSPKSSSPKQPVSYCTEQQASVQADPEDAPLLNSFHHALQMWQNTLSGGEKASTDLPARRAMNLYVQPSPGQRVLRAPATSNGSKVPPVGSHPEPARPAQGLTSAQATQGDEKGAGSSAATTLQPQCQKESKPPLCQPGAGTQLGNKPPKIRPLPSAASLGPAPRKPLRPPKVDLSSFRSTVPSVHRQNETTAEEEDYLIPESTQCEEQHNYEKTLMYLNQSEDTTTLRVIEVPKVEPQEHKKQKSFLFGESSPGRAIIEDEKEGKTSLEREKLEVKKPGGNEYIILSGQAREDDRGGMKVSHMRQDVTSTPQRLAKDRAKPLYYGAPKPTEDRPTSSPNHHQLLLTPDNVYDDVEGLQDRLRASDASSPSASDIRSNYEETYEDVETGSDNPAKEEAEKQKRFGKLFKIEKLKLKNTRFKENLRLFSMSVPNLADVSQEDMVYDDAETEQKDPREKDDKHKTWMPKFLMAKEAKDRRKSSDDVERSIFKVKKSNAEKNKMEKEEKIFRETFLYDKEIRVINTATAACSIPSKRRADLPLTAGEQLDVIDVTEGSAVICRNSEGRCKSVETLCHRWSAFNPVLRSKLTRQIILCVLC", "length": 639, "header": "tr|A0A8V1ABG7-1|A0A8V1ABG7_CHICK Computationally mapped isoform of FYN binding protein 2 OS=Gallus gallus OX=9031 GN=FYB2 PE=4 SV=1 CANONICAL=A0A8V1ADJ5-1" }, "locus": { "chromosome": "8", "start_pos": 25484695, "end_pos": 25469445, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010064661.1", "url": "https://www.ensembl.org/id/ENSGALT00010064661.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039580.1", "url": "https://www.ensembl.org/id/ENSGALP00010039580.1" } ] } }, { "isoform_ac": "A0A8V1ADJ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADJ5/entry#A0A8V1ADJ5-1", "sequence": { "sequence": "MPVQGSGAMDVEGVTDFRALRAKFQHDSSIATKPVQLCQKPSPRLGSGGSGVPRPMPNSKADVLVPGSHSAQRAKMGHTEPMEHNEEHKGNVSVKGLSSPKSSSPKQPVSYCTEQQASVQADPEDAPLLNSFHHALQMWQNTLSGGEKASTDLPARRAMNLYVQPSPGQRVLRAPATSNGSKVPPVGSHPEPARPAQGLTSAQATQGDEKGAGSSAATTLQPQCQKESKPPLCQPGAGTQLGNKPPKIRPLPSAASLGPAPRKPLRPPKVDLSSFRSTVPSVHRQNETTAEEEDYLIPESTQCEEQHNYEKTLMYLNQSEDTTTLRVIEVPKVEPQEHKKQKSFLFGESSPGRAIIEDEKEGKTSLEREKLEVKKPGGNEYIILSGQAREDDRGGMKVSHMRQDVTSTPQRLAKDRAKPLYYGAPKPTEDRPTSSPNHHQLLLTPDNVYDDVEGLQDRLSRASDASSPSASDIRSNYEETYEDVETGSDNPAKEEAEKQKRFGKLFKIEKLKLKNTRFKENLRLFSMSVPNLADVSQEDMVYDDAETEQKDPREKDDKHKTWMPKFLMAKEAKDRRKSSDDVERSIFKVKKSNAEKNKMEKEEKIFRETFLYDKEIRVINTATAACSIPSKRRADLPLTAGEQLDVIDVTEGSAVICRNSEGRYGYVLVEYLNFRQY", "length": 677, "header": "tr|A0A8V1ADJ5-1|A0A8V1ADJ5_CHICK Isoform 1 of FYN-binding protein 2 OS=Gallus gallus OX=9031 GN=FYB2 PE=4 SV=1 CANONICAL=A0A8V1ADJ5-1" }, "locus": { "chromosome": "8", "start_pos": 25487537, "end_pos": 25468892, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010064657.1", "url": "https://www.ensembl.org/id/ENSGALT00010064657.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039578.1", "url": "https://www.ensembl.org/id/ENSGALP00010039578.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:424668", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424668", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADJ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADJ5" } ], "pmid": "" }, { "name": "membrane raft", "id": "GO:0045121", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045121", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADJ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADJ5" } ], "pmid": "" }, { "name": "immunological synapse", "id": "GO:0001772", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001772", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADJ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADJ5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "integrin-mediated signaling pathway", "id": "GO:0007229", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007229", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADJ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADJ5" } ], "pmid": "" }, { "name": "protein localization to plasma membrane", "id": "GO:0072659", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072659", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADJ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADJ5" } ], "pmid": "" }, { "name": "T cell receptor signaling pathway", "id": "GO:0050852", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050852", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADJ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADJ5" } ], "pmid": "" }, { "name": "cell adhesion mediated by integrin", "id": "GO:0033627", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033627", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADJ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADJ5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 179, "end_pos": 181, "annotation": "n_glycosylation_sequon" }, { "start_pos": 286, "end_pos": 288, "annotation": "n_glycosylation_sequon" }, { "start_pos": 317, "end_pos": 319, "annotation": "n_glycosylation_sequon" }, { "start_pos": 91, "end_pos": 93, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1ADJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADJ5" }, { "id": "PF14603", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14603" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Helically-extended SH3", "eco_id": "ECO_0000259", "start_pos": 606, "end_pos": 672, "start_aa": "Phe", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 179, "end_pos": 181 }, { "start_pos": 286, "end_pos": 288 }, { "start_pos": 317, "end_pos": 319 }, { "start_pos": 91, "end_pos": 93 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1ADX4-1", "uniprot_ac": "A0A8V1ADX4", "uniprot_id": "A0A8V1ADX4_CHICK", "mass": { "chemical_mass": 140434.0, "monoisotopic_mass": 140434.0 }, "refseq": {}, "gene_names": [ { "name": "MAMDC4", "type": "recommended", "evidence": [ { "id": "A0A8V1ADX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADX4" } ] } ], "protein_names": [ { "name": "MAM domain containing 4", "type": "synonym", "evidence": [ { "id": "A0A8V1ADX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADX4/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADX4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADX4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MAMDC4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADX4", "locus": { "chromosome": "17", "start_pos": 1230499, "end_pos": 1240608, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028466", "url": "https://www.ensembl.org/id/ENSGALG00010028466" } ] } } ], "crossref": [ { "id": "cd00112", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00112", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd06263", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06263", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "101751695", "url": "https://www.ncbi.nlm.nih.gov/gene/101751695", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000998", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000998", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002172", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002172", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023415", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023415", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036055", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036055", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051560", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051560", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A8T6", "url": "https://www.orthodb.org/?gene=A0A8V1A8T6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ADX4", "url": "https://www.orthodb.org/?gene=A0A8V1ADX4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AKI8", "url": "https://www.orthodb.org/?gene=A0A8V1AKI8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23282", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23282", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23282:SF129", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23282:SF129", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00057", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00057", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00629", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00629", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1A8T6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8T6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A8T6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8T6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ADX4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADX4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ADX4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADX4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AKI8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKI8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AKI8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKI8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDRLDQPHRRCSALGLDAPWGGTQGAPVRVTALWEGTGFLTSTCPLSHLGVGPHLLLHLLQSHCAAAQITEGLKSRAEQVLGSRFQPGACGMASPGCCLSRLPSALLTSLLPVMSGLTLLLAMLLLAGAIPSSRAAAVNSCGSVAEHRCDFVCHCGDCSDENQCGYLGISAVLGSPFTCDFEDDDCGWRDVSTSTYRWVRGRASLDSWGTGPHSDHTMGTDQGWFMVTVSPPAKATATAWLQSPVMQEATATCEIWASYHLSGSGLNQTACPTLRLAVAFGDTVVELWRSPEHRAEGWHQLVAYPGRIKGQFQLTFALTQPPACGAVLALDDIVFRNCGLLAAGQQSCGAEESSCSRGSCLALGRFCDGTDDCGDGSDEDAEQCQFFTFCSFEEDLCSWEVEAGQPTWERNTSVGLGTTSGVPTRDHSTNSATGYFLHTVAGGAVSVARLSSPTFQATNSCSLVLYCHLHGSATSSLRISYVINSTEHLVRERTGDTGSCWVRERVDFNLKESFKVLITGEAGSGGSVAVDDLILSPGCVLQQDSAPVALPGRARASNCVAEEFSCDDGGCVSAELVCDFAKACADGSDENHCGTTTFEEGAGGWHDTSVGQLRWAVQRATEPTATALVGAGAFLALQRGEGQMVAPAKARTPLLGPSGLACAMEMSYRLHSGAQGFLAVAVTEHSTDMTHLAWHTRGHGSTAWEHVHIPLGERARPFQVELLGMAELQDPEAIAIANVTFVQCNPGVEPPEAAELSCNFEADLCGWYPDRGSDFQWVRSTGQGQGSDHTTGSGYFLAVDPSAPWSRGQHAQLITYRQEPAAAPQCLAFWYRLAGPQIGTLSLKLQLQGAEETVLWTQRGSQGSVWHRGLATLPATGQQRYRLAFEALRDGFVGDMALDDVALTPGACGAELSCSFEAGACGLAGSGQWHWQSGGTGTGPMADHTTGTTTGHYMVVNTSKHSLPMGHVATLSSALYQRSAPAQCLAFWYQLSAAAPGTLSILVEENGEQRKLFSISAMEGDTWHRGHVTVRADTDWKVVFEAVGAGSERSYMALDDLRVSDGACPEPASCDFEWDTCGWSSPSDERLHGFTWGWKSGVPLAKYPGPEQDHTLGTEDGHYVHFDTRVLGAGGTAARLESQHLPATTAGCLRFWYHMDIPEHLTGGELQVKLQSAAGQHTAWSVAGQRSQGWQSSTVPLESPSEFQIVFEITSRMWPMDGTVALDDIEYSATGGCDSNLEAPGKVKSSSSFVAEVVVGLLLAVIVLALVAAGGRYWLKRRAQESGMAMESNTPQGFDNITFQDDKVIIAQVPKERDED", "length": 1316, "header": "tr|A0A8V1ADX4-1|A0A8V1ADX4_CHICK Isoform 1 of MAM domain containing 4 OS=Gallus gallus OX=9031 GN=MAMDC4 PE=1 SV=1 CANONICAL=A0A8V1ADX4-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A8T6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADX4/entry#A0A8V1A8T6-1", "sequence": { "sequence": "MASPGCCLSRLPSALLTSLLPVMSGLTLLLAMLLLGWFMVTVSPPAKATATAWLQSPVMQEATATCEIWASYHLSGSGLNQTACPTLRLAVAFGDTVVELWRSPEHRAEGWHQLVAYPGRIKGQFQLTFALTQPPACGAVLALDDIVFRNCGLLAAGQQSCGAEESSCSRGSCLALGRFCDGTDDCGDGSDEDAEQCQFFTFCSFEEDLCSWEVEAGQPTWERNTSVGLGTTSGVPTRDHSTNSATGYFLHTVAGGAVSVARLSSPTFQATNSCSLVLYCHLHGSATSSLRISYVINSTEHLVRERTGDTGSCWVRERVDFNLKESFKVLITGEAGSGGSVAVDDLILSPGCVLQQDSAPVALPGRARASNCVAEEFSCDDGGCVSAELVCDFAKACADGSDENHCGTTTFEEGAGGWHDTSVGQLRWAVQRATEPTATALVGAGAFLALQRGEGQMVAPAKARTPLLGPSGLACAMEMSYRLHSGAQGFLAVAVTEHSTDMTHLAWHTRGHGSTAWEHVHIPLGERARPFQVELLGMAELQDPEAIAIANVTFVQCNPGVEPPEAAELSCNFEADLCGWYPDRGSDFQWVRSTGQGQGSDHTTGSGYFLAVDPSAPWSRGQHAQLITYRQEPAAAPQCLAFWYRLAGPQIGTLSLKLQLQGAEETVLWTQRGSQGSVWHRGLATLPATGQQRYRLAFEALRDGFVGDMALDDVALTPGACGAELSCSFEAGACGLAGSGQWHWQSGGTGTGPMADHTTGTTTGHYMVVNTSKHSLPMGHVATLSSALYQRSAPAQCLAFWYQLSAAAPGTLSILVEENGEQRKLFSISAMEGDTWHRGHVTVRADTDWKVVFEAVGAGSERSYMALDDLRVSDGACPEPASCDFEWDTCGWSSPSDERLHGFTWGWKSGVPLAKYPGPEQDHTLGTEDGHYVHFDTRVLGAGGTAARLESQHLPATTAGCLRFWYHMDIPEHLTGGELQVKLQSAAGQHTAWSVAGQRSQGWQSSTVPLESPSEFQIVFEITSRMWPMDGTVALDDIEYSATGGCDSNLEAPGKVKSSSSFVAEVVVGLLLAVIVLALVAAGGRYWLKRRAQESGMAMESNTPQGFDNITFQDDKVIIAQVPKERDED", "length": 1129, "header": "tr|A0A8V1A8T6-1|A0A8V1ADX4_CHICK Computationally mapped isoform of MAM domain containing 4 OS=Gallus gallus OX=9031 GN=MAMDC4 PE=1 SV=1 CANONICAL=A0A8V1ADX4-1" }, "locus": { "chromosome": "17", "start_pos": 1240136, "end_pos": 1230754, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068932.1", "url": "https://www.ensembl.org/id/ENSGALT00010068932.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042374.1", "url": "https://www.ensembl.org/id/ENSGALP00010042374.1" } ] } }, { "isoform_ac": "A0A8V1ADX4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADX4/entry#A0A8V1ADX4-1", "sequence": { "sequence": "MDRLDQPHRRCSALGLDAPWGGTQGAPVRVTALWEGTGFLTSTCPLSHLGVGPHLLLHLLQSHCAAAQITEGLKSRAEQVLGSRFQPGACGMASPGCCLSRLPSALLTSLLPVMSGLTLLLAMLLLAGAIPSSRAAAVNSCGSVAEHRCDFVCHCGDCSDENQCGYLGISAVLGSPFTCDFEDDDCGWRDVSTSTYRWVRGRASLDSWGTGPHSDHTMGTDQGWFMVTVSPPAKATATAWLQSPVMQEATATCEIWASYHLSGSGLNQTACPTLRLAVAFGDTVVELWRSPEHRAEGWHQLVAYPGRIKGQFQLTFALTQPPACGAVLALDDIVFRNCGLLAAGQQSCGAEESSCSRGSCLALGRFCDGTDDCGDGSDEDAEQCQFFTFCSFEEDLCSWEVEAGQPTWERNTSVGLGTTSGVPTRDHSTNSATGYFLHTVAGGAVSVARLSSPTFQATNSCSLVLYCHLHGSATSSLRISYVINSTEHLVRERTGDTGSCWVRERVDFNLKESFKVLITGEAGSGGSVAVDDLILSPGCVLQQDSAPVALPGRARASNCVAEEFSCDDGGCVSAELVCDFAKACADGSDENHCGTTTFEEGAGGWHDTSVGQLRWAVQRATEPTATALVGAGAFLALQRGEGQMVAPAKARTPLLGPSGLACAMEMSYRLHSGAQGFLAVAVTEHSTDMTHLAWHTRGHGSTAWEHVHIPLGERARPFQVELLGMAELQDPEAIAIANVTFVQCNPGVEPPEAAELSCNFEADLCGWYPDRGSDFQWVRSTGQGQGSDHTTGSGYFLAVDPSAPWSRGQHAQLITYRQEPAAAPQCLAFWYRLAGPQIGTLSLKLQLQGAEETVLWTQRGSQGSVWHRGLATLPATGQQRYRLAFEALRDGFVGDMALDDVALTPGACGAELSCSFEAGACGLAGSGQWHWQSGGTGTGPMADHTTGTTTGHYMVVNTSKHSLPMGHVATLSSALYQRSAPAQCLAFWYQLSAAAPGTLSILVEENGEQRKLFSISAMEGDTWHRGHVTVRADTDWKVVFEAVGAGSERSYMALDDLRVSDGACPEPASCDFEWDTCGWSSPSDERLHGFTWGWKSGVPLAKYPGPEQDHTLGTEDGHYVHFDTRVLGAGGTAARLESQHLPATTAGCLRFWYHMDIPEHLTGGELQVKLQSAAGQHTAWSVAGQRSQGWQSSTVPLESPSEFQIVFEITSRMWPMDGTVALDDIEYSATGGCDSNLEAPGKVKSSSSFVAEVVVGLLLAVIVLALVAAGGRYWLKRRAQESGMAMESNTPQGFDNITFQDDKVIIAQVPKERDED", "length": 1316, "header": "tr|A0A8V1ADX4-1|A0A8V1ADX4_CHICK Isoform 1 of MAM domain containing 4 OS=Gallus gallus OX=9031 GN=MAMDC4 PE=1 SV=1 CANONICAL=A0A8V1ADX4-1" }, "locus": { "chromosome": "17", "start_pos": 1240409, "end_pos": 1230754, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068934.1", "url": "https://www.ensembl.org/id/ENSGALT00010068934.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042376.1", "url": "https://www.ensembl.org/id/ENSGALP00010042376.1" } ] } }, { "isoform_ac": "A0A8V1AKI8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADX4/entry#A0A8V1AKI8-1", "sequence": { "sequence": "MASPGCCLSRLPSALLTSLLPVMSGLTLLLAMLLLAGAIPSSRAAAVNSCGSVAEHRCDFVCHCGDCSDENQCGYLGISAVLGSPFTCDFEDDDCGWRDVSTSTYRWVRGRASLDSWGTGPHSDHTMGTDQGWFMVTVSPPAKATATAWLQSPVMQEATATCEIWASYHLSGSGLNQTACPTLRLAVAFGDTVVELWRSPEHRAEGWHQLVAYPGRIKGQFQLTFALTQPPACGAVLALDDIVFRNCGLLAAGQQSCGAEESSCSRGSCLALGRFCDGTDDCGDGSDEDAEQCQFFTFCSFEEDLCSWEVEAGQPTWERNTSVGLGTTSGVPTRDHSTNSATGYFLHTVAGGAVSVARLSSPTFQATNSCSLVLYCHLHGSATSSLRISYVINSTEHLVRERTGDTGSCWVRERVDFNLKESFKVLITGEAGSGGSVAVDDLILSPGCVLQQGAFLALQRGEGQMVAPAKARTPLLGPSGLACAMEMSYRLHSGAQGFLAVAVTEHSTDMTHLAWHTRGHGSTAWEHVHIPLGERARPFQVELLGMAELQDPEAIAIANVTFVQCNPGVEPPEAAELSCNFEADLCGWYPDRGSDFQWVRSTGQGQGSDHTTGSGYFLAVDPSAPWSRGQHAQLITYRQEPAAAPQCLAFWYRLAGPQIGTLSLKLQLQGAEETVLWTQRGSQGSVWHRGLATLPATGQQRYRLAFEALRDGFVGDMALDDVALTPGACGAELSCSFEAGACGLAGSGQWHWQSGGTGTGPMADHTTGTTTGHYMVVNTSKHSLPMGHVATLSSALYQRSAPAQCLAFWYQLSAAAPGTLSILVEENGEQRKLFSISAMEGDTWHRGHVTVRADTDWKVVFEAVGAGSERSYMALDDLRVSDGACPEPASCDFEWDTCGWSSPSDERLHGFTWGWKSGVPLAKYPGPEQDHTLGTEDGHYVHFDTRVLGAGGTAARLESQHLPATTAGCLRFWYHMDIPEHLTGGELQVKLQSAAGQHTAWSVAGQRSQGWQSSTVPLESPSEFQIVFEITSRMWPMDGTVALDDIEYSATGGCDSNLEAPGKVKSSSSFVAEVVVGLLLAVIVLALVAAGGRYWLKRRAQESGMAMESNTPQGFDNITFQDDKVIIAQVPKERDED", "length": 1137, "header": "tr|A0A8V1AKI8-1|A0A8V1ADX4_CHICK Computationally mapped isoform of MAM domain containing 4 OS=Gallus gallus OX=9031 GN=MAMDC4 PE=1 SV=1 CANONICAL=A0A8V1ADX4-1" }, "locus": { "chromosome": "17", "start_pos": 1240136, "end_pos": 1230754, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068933.1", "url": "https://www.ensembl.org/id/ENSGALT00010068933.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042375.1", "url": "https://www.ensembl.org/id/ENSGALP00010042375.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADX4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADX4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1296, "end_pos": 1298, "annotation": "n_glycosylation_sequon" }, { "start_pos": 267, "end_pos": 269, "annotation": "n_glycosylation_sequon" }, { "start_pos": 411, "end_pos": 413, "annotation": "n_glycosylation_sequon" }, { "start_pos": 484, "end_pos": 486, "annotation": "n_glycosylation_sequon" }, { "start_pos": 738, "end_pos": 740, "annotation": "n_glycosylation_sequon" }, { "start_pos": 957, "end_pos": 959, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1ADX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADX4" }, { "id": "PS50060", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50060" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "MAM", "eco_id": "ECO_0000259", "start_pos": 177, "end_pos": 340, "start_aa": "Phe", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1296, "end_pos": 1298 }, { "start_pos": 267, "end_pos": 269 }, { "start_pos": 411, "end_pos": 413 }, { "start_pos": 484, "end_pos": 486 }, { "start_pos": 738, "end_pos": 740 }, { "start_pos": 957, "end_pos": 959 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1ABB4-1", "uniprot_ac": "A0A8V1ABB4", "uniprot_id": "A0A8V1ABB4_CHICK", "mass": { "chemical_mass": 38559.0, "monoisotopic_mass": 38559.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "G-protein coupled receptors family 1 profile domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8V1ABB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABB4/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABB4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABB4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABB4", "locus": {} } ], "crossref": [ { "id": "A0A8V1ABB4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1ABB4", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR24232", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24232", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24232:SF97", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24232:SF97", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00001", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00001", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-373076", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-373076", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1A8T9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8T9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A8T9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8T9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ABB4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABB4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ABB4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABB4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MCSSLSRTSVSSFGSQTITCHPHTRTMNESKSCNLTDIQVNPHVRLIEFAIYILTFFFGAIFNVLALWVFFCKIKKWTETKVYAINLVFADFFVICILPFMAYLIWKNSVRDELCQFIEAMYFINMVVSIYVISFIFIDRYLGIKHPLKARAFRSPSKAALLCGLLWLAVTTGTILNFQQRYADFCFQYDTSKPTALILLSIFFIFTLPLATLTFCSIEIIRNLKKQLKTNALEEKSIQKALYIIYANLVVFLLCFLPSHLIVIARLVTEHTETCSFNHFVKNFSSMTRCIATSNCCLDSICYYFVTKEFQEAILLPKSSTAKTTQTRSVQTHVY", "length": 335, "header": "tr|A0A8V1ABB4-1|A0A8V1ABB4_CHICK Isoform 1 of G-protein coupled receptors family 1 profile domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1ABB4-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A8T9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABB4/entry#A0A8V1A8T9-1", "sequence": { "sequence": "MNESKSCNLTDIQVNPHVRLIEFAIYILTFFFGAIFNVLALWVFFCKIKKWTETKVYAINLVFADFFVICILPFMAYLIWKNSVRDELCQFIEAMYFINMVVSIYVISFIFIDRYLGIKHPLKARAFRSPSKAALLCGLLWLAVTTGTILNFQQRYADFCFQYDTSKPTALILLSIFFIFTLPLATLTFCSIEIIRNLKKQLKTNALEEKSIQKALYIIYANLVVFLLCFLPSHLIVIARLVTEHTETCSFNHFVKNFSSMTRCIATSNCCLDSICYYFVTKEFQEAILLPKSSTAKTTQTRSVQTHVY", "length": 309, "header": "tr|A0A8V1A8T9-1|A0A8V1ABB4_CHICK Computationally mapped isoform of G-protein coupled receptors family 1 profile domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1ABB4-1" }, "locus": { "chromosome": "9", "start_pos": 4979980, "end_pos": 4979054, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010062624.1", "url": "https://www.ensembl.org/id/ENSGALT00010062624.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038718.1", "url": "https://www.ensembl.org/id/ENSGALP00010038718.1" } ] } }, { "isoform_ac": "A0A8V1ABB4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABB4/entry#A0A8V1ABB4-1", "sequence": { "sequence": "MCSSLSRTSVSSFGSQTITCHPHTRTMNESKSCNLTDIQVNPHVRLIEFAIYILTFFFGAIFNVLALWVFFCKIKKWTETKVYAINLVFADFFVICILPFMAYLIWKNSVRDELCQFIEAMYFINMVVSIYVISFIFIDRYLGIKHPLKARAFRSPSKAALLCGLLWLAVTTGTILNFQQRYADFCFQYDTSKPTALILLSIFFIFTLPLATLTFCSIEIIRNLKKQLKTNALEEKSIQKALYIIYANLVVFLLCFLPSHLIVIARLVTEHTETCSFNHFVKNFSSMTRCIATSNCCLDSICYYFVTKEFQEAILLPKSSTAKTTQTRSVQTHVY", "length": 335, "header": "tr|A0A8V1ABB4-1|A0A8V1ABB4_CHICK Isoform 1 of G-protein coupled receptors family 1 profile domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1ABB4-1" }, "locus": { "chromosome": "9", "start_pos": 4979980, "end_pos": 4978316, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010062621.1", "url": "https://www.ensembl.org/id/ENSGALT00010062621.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038716.1", "url": "https://www.ensembl.org/id/ENSGALP00010038716.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-373076", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-373076", "resource": "Reactome", "description": "Class A/1 (Rhodopsin-like receptors)" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABB4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABB4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABB4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABB4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "G protein-coupled receptor signaling pathway", "id": "GO:0007186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007186", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABB4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABB4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 283, "end_pos": 285, "annotation": "n_glycosylation_sequon" }, { "start_pos": 28, "end_pos": 30, "annotation": "n_glycosylation_sequon" }, { "start_pos": 34, "end_pos": 36, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1ABB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABB4" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 62, "end_pos": 303, "start_aa": "Phe", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 283, "end_pos": 285 }, { "start_pos": 28, "end_pos": 30 }, { "start_pos": 34, "end_pos": 36 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1ADY4-1", "uniprot_ac": "A0A8V1ADY4", "uniprot_id": "A0A8V1ADY4_CHICK", "mass": { "chemical_mass": 155539.0, "monoisotopic_mass": 155539.0 }, "refseq": {}, "gene_names": [ { "name": "RPRD2", "type": "recommended", "evidence": [ { "id": "A0A8V1ADY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADY4" } ] } ], "protein_names": [ { "name": "Regulation of nuclear pre-mRNA domain-containing protein 2", "type": "recommended", "evidence": [ { "id": "A0A8V1ADY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADY4/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADY4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADY4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RPRD2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADY4", "locus": { "chromosome": "25", "start_pos": 2275063, "end_pos": 2291757, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028472", "url": "https://www.ensembl.org/id/ENSGALG00010028472" } ] } } ], "crossref": [ { "id": "cd17001", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17001", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "425074", "url": "https://www.ncbi.nlm.nih.gov/gene/425074", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006569", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006569", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008942", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008942", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047885", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047885", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A8U5", "url": "https://www.orthodb.org/?gene=A0A8V1A8U5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A8V0", "url": "https://www.orthodb.org/?gene=A0A8V1A8V0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ADY4", "url": "https://www.orthodb.org/?gene=A0A8V1ADY4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AGH6", "url": "https://www.orthodb.org/?gene=A0A8V1AGH6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12460", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12460", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12460:SF40", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12460:SF40", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04818", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04818", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-6807505", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6807505", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1A8U5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8U5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A8U5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8U5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A8V0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8V0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A8V0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8V0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ADY4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADY4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ADY4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADY4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGH6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGH6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGH6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGH6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAGGGGGGRASSSAASSSAGALEASLDRKLQAVTNTMESIQGLSSWCLENKRHHNTIVYHWMKWLRRSAFPHRLNLFYLANDVIQNCKRKNAIVFRDTFAEVLPEAASLVKDPSVSKSIERIFKIWEDRNVYPEETILALKEALSTTFKTQKQLKETLNKQPNKPWKKSQTSANPKAALKSKIVAEFRPQSLIDELLLYKRSEDQIELKEKQLSTMRVDVCSTETLKCLKDKTGGKKFSKEFEEASSKLEEFVNGLDKQVKNGPSLTEALENAGIFYEAQYKEVKVVANAYKTFANRVSNLKKKLDQLKATLPDPEESPVPSPSMDAPSPTGSESPFQGMGEEDNSHSPAVGSRKPGSPEPVTDNRDVEDMELSDVEDDTSKIIVEERKEKQAAPASAPVKTENTPKVVPCTAATATTSVTVTAPAPTPPAPKPVSAAPISSSPALALPNLANVDLAKISSILSSLTSVMKNTGVSPASRPSPGTPTSPTALTSGLKTPAMGTPSAPSNPLANILSKVEITPESILSALSKTQTQTAPALQGLSSLLQSVAGNTIQSSETASQSTSASPANTTVPCLKGRNIPSNTQSFVSKNFGYSPNSSTAEVSSTSVNKAPVGHTAGLSSSGFKPPTNSLGFSSSHPPSSSSLLTTDASMSQSSEISKAKLESEPPSPSLEMKIHNFLKGNPGFSGLNLNIPILSSLGSNIAPESHSSDFQRGPTSTSMDNVDGTPVRDERSGTPTQDEMMDKPTSSNVDTISLLSKIMSPGSSTPSSTRSPLQSRDDGYPQELPNSVHTYRPFSLGRDSPAGMYKQSADSMEIPSSLMDSSQEKFYPDTSFQEDEDYRDFDYSGPPPSAMLNLEKKPAKSILKSSKLSEGAEYQPVLPSYGQRSQDFSVKSSFPQSMRSILDQSESCDTLSTSPGMYGSYSLRGNDSTSDGSPSPSKNDVFFTPDSNHNNLPKPVVHSGLSQKQYPDSPHSIPHRSLFSSQSTLPNPAGRPPAPGVDKSLGSSISATSTMEFKNMLKNASRKPSEEKHFSQISKGSSNEGVGHSQAGAPKGEQQQQQQQQQQEEHYRIETRVSSSCLDLPDSTEEKGAPIETLGYHNASSRGMSGEPIQTVESIRVLGKGSRGHGREASRSGWFEISNTGSAFDNGPSSASELPGMGGFQAQYKERVPPFQESVNNFRTNNFSPAFDHHMPPPIAPPPMEHGTPFPRDPVGPPAGPPAAPPKDHGSLFPRDHSVPPHMPPVDHANPFSKETSSPLSLPHGVPPPPTVEHTGVPFPTPPPPPVPGEHAGVPFPSQPPPAGEHGSVPFPAPPLTVEHGGSAFPKEHGTVHQGTMKEHFNVHAGPREPTQPQRDHGGASLGRVREGVGMASLGREQLGPTRSVTPIGPAHRDGANRGGMMVRTPRADFRPREPFMNRDPFHSLKRPRPTFGRGSPFFAPKRPFFPPRY", "length": 1450, "header": "tr|A0A8V1ADY4-1|A0A8V1ADY4_CHICK Isoform 1 of Regulation of nuclear pre-mRNA domain-containing protein 2 OS=Gallus gallus OX=9031 GN=RPRD2 PE=1 SV=1 CANONICAL=A0A8V1ADY4-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A8U5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADY4/entry#A0A8V1A8U5-1", "sequence": { "sequence": "MAAGGGGGGRASSSAASSSAGALEASLDRKLQAVTNTMESIQGLSSWCLENKRHHNTIVYHWMKWLRRCECGQRSGRAGPPLSPPVLLSAFGLLESGPGLRAGPPAAGRWMRAAPGEGFLLLRGFLSSHTLWEPRSGFPIPCSKGFSRAVLLGRAVSVSGGGAVGKGQLRGCLPLAECCRSSGLAVWLSRVPTARQRRGAVMVVLVLCQSCPAQLEGALRSDVR", "length": 224, "header": "tr|A0A8V1A8U5-1|A0A8V1ADY4_CHICK Computationally mapped isoform of Regulation of nuclear pre-mRNA domain-containing protein 2 OS=Gallus gallus OX=9031 GN=RPRD2 PE=1 SV=1 CANONICAL=A0A8V1ADY4-1" }, "locus": { "chromosome": "25", "start_pos": 2289026, "end_pos": 2288355, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068942.1", "url": "https://www.ensembl.org/id/ENSGALT00010068942.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042384.1", "url": "https://www.ensembl.org/id/ENSGALP00010042384.1" } ] } }, { "isoform_ac": "A0A8V1A8V0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADY4/entry#A0A8V1A8V0-1", "sequence": { "sequence": "MAAGGGGGGRASSSAASSSAGALEASLDRKLQAVTNTMESIQGLSSWCLENKRHHNTIVYHWMKWLRRSAFPHRLNLFYLANDVIQNCKRKNAIVFRDTFAEVLPEAASLVKDPSVSKSIERIFKIWEDRNVYPEETILALKEALSTTFKTQKQLKETLNKQPNKPWKKSQTSANPKAALKSKIVAEFRPQSLIDELLLYKRSEDQIELKEKQLSTMRVDVCSTETLKCLKDKTGGKKFSKEFEEASSKLEEFVNGLDKQVKNGPSLTEALENAGIFYEAQYKEVKVVANAYKTFANRVSNLKKKLDQLKATLPDPEESPVPSPTVGSRKPGSPEPVTDNRDVEDMELSDVEDDTSKIIVEERKEKQAAPASAPVKTENTPKVVPCTAATATTSVTVTAPAPTPPAPKPVSAAPISSSPALALPNLANVDLAKISSILSSLTSVMKNTGVSPASRPSPGTPTSPTALTSGLKTPAMGTPSAPSNPLANILSKVEITPESILSALSKTQTQTAPALQGLSSLLQSVAGNTIQSSETASQSTSASPANTTVPCLKGRNIPSNTQSFVSKNFGYSPNSSTAEVSSTSVNKAPVGHTAGLSSSGFKPPTNSLGFSSSHPPSSSSLLTTDASMSQSSEISKAKLESEPPSPSLEMKIHNFLKGNPGFSGLNLNIPILSSLGSNIAPESHSSDFQRGPTSTSMDNVDGTPVRDERSGTPTQDEMMDKPTSSNVDTISLLSKIMSPGSSTPSSTRSPLQSRDDGYPQELPNSVHTYRPFSLGRDSPAGMYKQSADSMEIPSSLMDSSQEKFYPDTSFQEDEDYRDFDYSGPPPSAMLNLEKKPAKSILKSSKLSEGAEYQPVLPSYGQRSQDFSVKSSFPQSMRSILDQSESCDTLSTSPGMYGSYSLRGNDSTSDGSPSPSKNDVFFTPDSNHNNLPKPVVHSGLSQKQYPDSPHSIPHRSLFSSQSTLPNPAGRPPAPGVDKSLGSSISATSTMEFKNMLKNASRKPSEEKHFSQISKGSSNEGVGHSQAGAPKGEQQQQQQQQQQEEHYRIETRVSSSCLDLPDSTEEKGAPIETLGYHNASSRGMSGEPIQTVESIRVLGKGSRGHGREASRSGWFEISNTGSAFDNGPSSASELPGMGGFQAQYKERVPPFQESVNNFRTNNFSPAFDHHMPPPIAPPPMEHGTPFPRDPVGPPAGPPAAPPKDHGSLFPRDHSVPPHMPPVDHANPFSKETSSPLSLPHGVPPPPTVEHTGVPFPTPPPPPVPGEHAGVPFPSQPPPAGEHGSVPFPAPPLTVEHGGSAFPKEHGTVHQGTMKEHFNVHAGPREPTQPQRDHGGASLGRVREGVGMASLGREQLGPTRSVTPIGPAHRDGANRGGMMVRTPRADFRPREPFMNRDPFHSLKRPRPTFGRGSPFFAPKRPFFPPRY", "length": 1424, "header": "tr|A0A8V1A8V0-1|A0A8V1ADY4_CHICK Computationally mapped isoform of Regulation of nuclear pre-mRNA domain-containing protein 2 OS=Gallus gallus OX=9031 GN=RPRD2 PE=1 SV=1 CANONICAL=A0A8V1ADY4-1" }, "locus": { "chromosome": "25", "start_pos": 2291645, "end_pos": 2276255, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068947.1", "url": "https://www.ensembl.org/id/ENSGALT00010068947.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042389.1", "url": "https://www.ensembl.org/id/ENSGALP00010042389.1" } ] } }, { "isoform_ac": "A0A8V1ADY4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADY4/entry#A0A8V1ADY4-1", "sequence": { "sequence": 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"MAAGGGGGGRASSSAASSSAGALEASLDRKLQAVTNTMESIQGLSSWCLENKRHHNTIVYHWMKWLRRSAFPHRLNLFYLANDVIQNCKRKNAIVFRDTFAEVLPEAASLVKDPSVSKSIERIFKIWEDRNVYPEETILALKEALTASANPKAALKSKIVAEFRPQSLIDELLLYKRSEDQIELKEKQLSTMRVDVCSTETLKCLKDKTGGKKFSKEFEEASSKLEEFVNGLDKQVKNGPSLTEALENAGIFYEAQYKEVKVVANAYKTFANRVSNLKKKLDQLKATLPDPEESPVPSPSMDAPSPTGSESPFQGMGEEDNSHSPAVGSRKPGSPEPVTDNRDVEDMELSDVEDDTSKIIVEERKEKQAAPASAPVKTENTPKVVPCTAATATTSVTVTAPAPTPPAPKPVSAAPISSSPALALPNLANVDLAKISSILSSLTSVMKNTGVSPASRPSPGTPTSPTALTSGLKTPAMGTPSAPSNPLANILSKVEITPESILSALSKTQTQTAPALQGLSSLLQSVAGNTIQSSETASQSTSASPANTTVPCLKGRNIPSNTQSFVSKNFGYSPNSSTAEVSSTSVNKAPVGHTAGLSSSGFKPPTNSLGFSSSHPPSSSSLLTTDASMSQSSEISKAKLESEPPSPSLEMKIHNFLKGNPGFSGLNLNIPILSSLGSNIAPESHSSDFQRGPTSTSMDNVDGTPVRDERSGTPTQDEMMDKPTSSNVDTISLLSKIMSPGSSTPSSTRSPLQSRDDGYPQELPNSVHTYRPFSLGRDSPAGMYKQSADSMEIPSSLMDSSQEKFYPDTSFQEDEDYRDFDYSGPPPSAMLNLEKKPAKSILKSSKLSEGAEYQPVLPSYGQRSQDFSVKSSFPQSMRSILDQSESCDTLSTSPGMYGSYSLRGNDSTSDGSPSPSKNDVFFTPDSNHNNLPKPVVHSGLSQKQYPDSPHSIPHRSLFSSQSTLPNPAGRPPAPGVDKSLGSSISATSTMEFKNMLKNASRKPSEEKHFSQISKGSSNEGVGHSQAGAPKGEQQQQQQQQQQEEHYRIETRVSSSCLDLPDSTEEKGAPIETLGYHNASSRGMSGEPIQTVESIRVLGKGSRGHGREASRSGWFEISNTGSAFDNGPSSASELPGMGGFQAQYKERVPPFQESVNNFRTNNFSPAFDHHMPPPIAPPPMEHGTPFPRDPVGPPAGPPAAPPKDHGSLFPRDHSVPPHMPPVDHANPFSKETSSPLSLPHGVPPPPTVEHTGVPFPTPPPPPVPGEHAGVPFPSQPPPAGEHGSVPFPAPPLTVEHGGSAFPKEHGTVHQGTMKEHFNVHAGPREPTQPQRDHGGASLGRVREGVGMASLGREQLGPTRSVTPIGPAHRDGANRGGMMVRTPRADFRPREPFMNRDPFHSLKRPRPTFGRGSPFFAPKRPFFPPRY", "length": 1425, "header": "tr|A0A8V1AGH6-1|A0A8V1ADY4_CHICK Computationally mapped isoform of Regulation of nuclear pre-mRNA domain-containing protein 2 OS=Gallus gallus OX=9031 GN=RPRD2 PE=1 SV=1 CANONICAL=A0A8V1ADY4-1" }, "locus": { "chromosome": "25", "start_pos": 2291645, "end_pos": 2276255, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068946.1", "url": "https://www.ensembl.org/id/ENSGALT00010068946.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042388.1", "url": "https://www.ensembl.org/id/ENSGALP00010042388.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1271, "start_aa": "Thr", "end_pos": 1271, "end_aa": "Thr", "residue": "Thr", 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"end_pos": 429, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr429", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 504, "start_aa": "Thr", "end_pos": 504, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr504", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 769, "start_aa": "Thr", "end_pos": 769, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr769", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-GGA-6807505", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6807505", "resource": "Reactome", "description": "RNA polymerase II transcribes snRNA genes" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA polymerase II C-terminal domain binding", "id": "GO:0099122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099122", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADY4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADY4" } ], "pmid": "" }, { "name": "RNA polymerase II complex binding", "id": "GO:0000993", "url": 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"n_glycosylation_sequon" }, { "start_pos": 1186, "end_pos": 1188, "annotation": "n_glycosylation_sequon" }, { "start_pos": 572, "end_pos": 574, "annotation": "n_glycosylation_sequon" }, { "start_pos": 600, "end_pos": 602, "annotation": "n_glycosylation_sequon" }, { "start_pos": 930, "end_pos": 932, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1ADY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADY4" }, { "id": "PS51391", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51391" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CID", "eco_id": "ECO_0000259", "start_pos": 19, "end_pos": 149, "start_aa": "Ser", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 429, 504, 769, 1271, 1281 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1023, "end_pos": 1025 }, { "start_pos": 1102, "end_pos": 1104 }, { "start_pos": 1186, "end_pos": 1188 }, { "start_pos": 572, "end_pos": 574 }, { "start_pos": 600, "end_pos": 602 }, { "start_pos": 930, "end_pos": 932 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 5 }, { "field": "total_sites", "count": 5 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 5 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", 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"https://www.uniprot.org/uniprotkb/A0A8V1AE11" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "EXD3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE11", "locus": { "chromosome": "17", "start_pos": 1335151, "end_pos": 1577610, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028483", "url": "https://www.ensembl.org/id/ENSGALG00010028483" } ] } } ], "crossref": [ { "id": "A0A8V1AE11", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AE11", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd06146", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06146", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "417283", "url": "https://www.ncbi.nlm.nih.gov/gene/417283", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002562", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002562", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002782", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002782", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012337", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012337", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036397", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036397", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037432", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037432", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052408", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052408", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A8X1", "url": "https://www.orthodb.org/?gene=A0A8V1A8X1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AE11", "url": "https://www.orthodb.org/?gene=A0A8V1AE11", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AGJ2", "url": "https://www.orthodb.org/?gene=A0A8V1AGJ2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AIT1", "url": "https://www.orthodb.org/?gene=A0A8V1AIT1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AIT6", "url": "https://www.orthodb.org/?gene=A0A8V1AIT6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AKL3", "url": "https://www.orthodb.org/?gene=A0A8V1AKL3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47765", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47765", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47765:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47765:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01612", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01612", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01927", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01927", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1A8X1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8X1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A8X1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8X1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AE11", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE11", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AE11-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE11-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGJ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGJ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGJ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGJ2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AIT1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIT1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AIT1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIT1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AIT6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIT6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AIT6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIT6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AKL3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKL3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AKL3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKL3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSQEGNSGDRPAGQDPLLLLKTLQLLWTKKEMKKLKEEIRRGFAGLEDPLAGLLDMLESNGDWKGKGHSLGYYISSELQLWMKEHPAVQQSGMKLKKLQARVFRILDQCPANLLDPLISIYQLHTADRNYLLGHVSHLYHRGDYKEAAILSIKLKLQPDQDVEKMCAPLLFQDKINLVEDYVAEYPELQCRLLEILDTWCEPDFNIRDMARQYQGLSRYKPDKLNRKMLSKLIFRLLDRFNVDPALCPNVINQRHLRTLNYLFYKRFVEKTMTQENWADHIQSTVGENRWLQGHLIQLLLRYCDLNTAARWAQRCSLPEEVLPSEVADELQKLEIQERVEEATKEENYKEVKKKDYYQLPIPRANIRLLQNWEEMMQCYEKVLKPGQIVGIDMEWRPSFGMVGKPRVSLLQLAVRDEVFLLDLPRLLEQAEVKGEKEKLPHFIQRLYSDATITKLGYGMSGDLSSLAATCSTLKGMDKQSQSVVDLLTIDKLLQKSSTDWKKGGLKVDVLSPEQSCEDGGLRQPEKGLSLLVQHVLGKPLDKTEQMSNWEKRPLREEQILYAASDAYCLLEVYEKLCKDPESFGLSSDLTESLVGKPSVKPRAKKQLNKQEVPSPSGQQCKGSDKETSCPPAPISPKEFSVVCDNMLQGLGRYLRCLGVDVRMLENEDDHRKAAEIARQEGRVILTSGLPYQTLRSHVGEGRCFSVNCSEKAKEQALQVLKHFNVHVTLADIFSRCQVSQQVRGHCIAQEQVCFLGCHHAFTTPDPCRPRAQCWRQAAGSPAGLKAVCEPSRPILTYGSSVITSALPPWRAPAVSGPSQFGQQWEAQGRGLGGRGSWPCPRLSSAPPLCTSSCHIRASCWAKPDDPSLTAAIAKKRDFLKSAAPPVQESS", "length": 890, "header": "tr|A0A8V1AE11-1|A0A8V1AE11_CHICK Isoform 1 of Exonuclease 3'-5' domain containing 3 OS=Gallus gallus OX=9031 GN=EXD3 PE=1 SV=1 CANONICAL=A0A8V1AE11-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A8X1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE11/entry#A0A8V1A8X1-1", "sequence": { "sequence": "MSQEGNSGDRPAGQDPLLLLKTLQLLWTKKEMKKQLKEEIRRGFAGLEDPLAGLLDMLESNGDWKGKGHSLGYYISSELQLWMKEHPAVQQSGMKLKKLQARVFRILDQCPANLLDPLISIYQLHTADRNYLLGHVSHLYHRGDYKEAAILSIKLKLQPDQDVEKMCAPLLFQDKINLVEDYVAEYPELQCRLLEILDTWCEPDFNIRDMARQYQGLSRYKPDKLNRKMLSKLIFRLLDRFNVDPALCPNVINQRHLRTLNYLFYKRFVEKTMTQENWADHIQSTVGENRWLQGHLIQLLLRYCDLNTAARWAQRCSLPEEVLPSEVADELQKLEIQERVEEATKEENYKEVKKKDYYQLPIPRANIRLLQNWEEMMQCYEKVLKPGQIVGIDMEWRPSFGMVGKPRVSLLQLAVRDEVFLLDLPRLLEQAEVKGEKEKLPHFIQRLYSDATITKLGYGMSGDLSSLAATCSTLKGMDKQSQSVVDLLTIDKLLQKSSTDWKKGGLKVDVLSPEQSCEDGGLRQPEKGLSLLVQHVLGKPLDKTEQMSNWEKRPLREEQILYAASDAYCLLEVYEKLCKDPESFGLSSDLTESLVGKPSVKPRAKKQLNKQEVPSPSGQQCKGSDKETSCPPAPISPKEFSVVCDNMLQGLGRYLRCLGVDVRMLENEDDHRKAAEIARQEGRVILTSGLPYQTLRSHVGEGRCFSVNCSEKAKEQALQVLKHFNVHVTLADIFSRCQVSQQVRGHCIAQEQVCFLGCHHAFTTPDPCRPRAQCWRQAAGSPAGLKAVCEPSRPILTYGSSVITSALPPWRAPAVSGPSQFGQQWEAQGRGLGGRGSWPCPRLSSAPPLCTSSCHIRASCWVRIASRLTQNFPPVSWLRVMAQKCF", "length": 886, "header": "tr|A0A8V1A8X1-1|A0A8V1AE11_CHICK Computationally mapped isoform of Exonuclease 3'-5' domain containing 3 OS=Gallus gallus OX=9031 GN=EXD3 PE=1 SV=1 CANONICAL=A0A8V1AE11-1" }, "locus": { "chromosome": "17", "start_pos": 1521216, "end_pos": 1359210, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068967.1", "url": "https://www.ensembl.org/id/ENSGALT00010068967.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042409.1", "url": "https://www.ensembl.org/id/ENSGALP00010042409.1" } ] } }, { "isoform_ac": "A0A8V1AE11-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE11/entry#A0A8V1AE11-1", "sequence": { "sequence": "MSQEGNSGDRPAGQDPLLLLKTLQLLWTKKEMKKLKEEIRRGFAGLEDPLAGLLDMLESNGDWKGKGHSLGYYISSELQLWMKEHPAVQQSGMKLKKLQARVFRILDQCPANLLDPLISIYQLHTADRNYLLGHVSHLYHRGDYKEAAILSIKLKLQPDQDVEKMCAPLLFQDKINLVEDYVAEYPELQCRLLEILDTWCEPDFNIRDMARQYQGLSRYKPDKLNRKMLSKLIFRLLDRFNVDPALCPNVINQRHLRTLNYLFYKRFVEKTMTQENWADHIQSTVGENRWLQGHLIQLLLRYCDLNTAARWAQRCSLPEEVLPSEVADELQKLEIQERVEEATKEENYKEVKKKDYYQLPIPRANIRLLQNWEEMMQCYEKVLKPGQIVGIDMEWRPSFGMVGKPRVSLLQLAVRDEVFLLDLPRLLEQAEVKGEKEKLPHFIQRLYSDATITKLGYGMSGDLSSLAATCSTLKGMDKQSQSVVDLLTIDKLLQKSSTDWKKGGLKVDVLSPEQSCEDGGLRQPEKGLSLLVQHVLGKPLDKTEQMSNWEKRPLREEQILYAASDAYCLLEVYEKLCKDPESFGLSSDLTESLVGKPSVKPRAKKQLNKQEVPSPSGQQCKGSDKETSCPPAPISPKEFSVVCDNMLQGLGRYLRCLGVDVRMLENEDDHRKAAEIARQEGRVILTSGLPYQTLRSHVGEGRCFSVNCSEKAKEQALQVLKHFNVHVTLADIFSRCQVSQQVRGHCIAQEQVCFLGCHHAFTTPDPCRPRAQCWRQAAGSPAGLKAVCEPSRPILTYGSSVITSALPPWRAPAVSGPSQFGQQWEAQGRGLGGRGSWPCPRLSSAPPLCTSSCHIRASCWAKPDDPSLTAAIAKKRDFLKSAAPPVQESS", "length": 890, "header": "tr|A0A8V1AE11-1|A0A8V1AE11_CHICK Isoform 1 of Exonuclease 3'-5' domain containing 3 OS=Gallus gallus OX=9031 GN=EXD3 PE=1 SV=1 CANONICAL=A0A8V1AE11-1" }, "locus": { "chromosome": "17", "start_pos": 1521216, "end_pos": 1358832, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068969.1", "url": "https://www.ensembl.org/id/ENSGALT00010068969.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042411.1", "url": "https://www.ensembl.org/id/ENSGALP00010042411.1" } ] } }, { "isoform_ac": "A0A8V1AGJ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE11/entry#A0A8V1AGJ2-1", "sequence": { "sequence": "MPLLHPANPPSSLETTSNLKEEIRRGFAGLEDPLAGLLDMLESNGDWKGKGHSLGYYISSELQLWMKEHPAVQQSGMKLKKLQARVFRILDQCPANLLDPLISIYQLHTADRNYLLGHVSHLYHRGDYKEAAILSIKLKLQPDQDVEKMCAPLLFQDKINLVEDYVAEYPELQCRLLEILDTWCEPDFNIRDMARQYQGLSRYKPDKLNRKMLSKLIFRLLDRFNVDPALCPNVINQRHLRTLNYLFYKRFVEKTMTQENWADHIQSTVGENRWLQGHLIQLLLRYCDLNTAARWAQRCSLPEEVLPSEVADELQKLEIQERVEEATKEENYKEVKKKDYYQLPIPRANIRLLQNWEEMMQCYEKVLKPGQIVGIDMEWRPSFGMVGKPRVSLLQLAVRDEVFLLDLPRLLEQAEVKGEKEKLPHFIQRLYSDATITKLGYGMSGDLSSLAATCSTLKGMDKQSQSVVDLLTIDKLLQKSSTDWKKGGLKVDVLSPEQSCEDGGLRQPEKGLSLLVQHVLGKPLDKTEQMSNWEKRPLREEQILYAASDAYCLLEVYEKLCKDPESFGLSSDLTESLVGKPSVKPRAKKQLNKQEVPSPSGQQCKGSDKETSCPPAPISPKEFSVVCDNMLQGLGRYLRCLGVDVRMLENEDDHRKAAEIARQEGRVILTSGLPYQTLRSHVGEGRCFSVNCSEKAKEQALQVLKHFNVHVTLADIFSRCQVSQQVRGHCIAQEQVCFLGCHHAFTTPDPCRPRAQCWRQAAGSPAGLKAVCEPSRPILTYGSSVITSALPPWRAPAVSGPSQFGQQWEAQGRGLGGRGSWPCPRLSSAPPLCTSSCHIRASCWVRIASRLTQNFPPVSWLRVMAQKCF", "length": 869, "header": "tr|A0A8V1AGJ2-1|A0A8V1AE11_CHICK Computationally mapped isoform of Exonuclease 3'-5' domain containing 3 OS=Gallus gallus OX=9031 GN=EXD3 PE=1 SV=1 CANONICAL=A0A8V1AE11-1" }, "locus": { "chromosome": "17", "start_pos": 1494683, "end_pos": 1359210, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068966.1", "url": "https://www.ensembl.org/id/ENSGALT00010068966.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042408.1", "url": "https://www.ensembl.org/id/ENSGALP00010042408.1" } ] } }, { "isoform_ac": "A0A8V1AIT1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE11/entry#A0A8V1AIT1-1", "sequence": { "sequence": "MEDGLGMPKAGAGQDPLLLLKTLQLLWTKKEMKKQLKEEIRRGFAGLEDPLAGLLDMLESNGDWKGKGHSLGYYISSELQLWMKEHPAVQQSGMKLKKLQARVFRILDQCPANLLDPLISIYQLHTADRNYLLGHVSHLYHRGDYKEAAILSIKLKLQPDQDVEKMCAPLLFQDKINLVEDYVAEYPELQCRLLEILDTWCEPDFNIRDMARQYQGLSRYKPDKLNRKMLSKLIFRLLDRFNVDPALCPNVINQRHLRTLNYLFYKRFVEKTMTQENWADHIQSTVGENRWLQGHLIQLLLRYCDLNTAARWAQRCSLPEEVLPSEVADELQKLEIQERVEEATKEENYKEVKKKDYYQLPIPRANIRLLQNWEEMMQCYEKVLKPGQIVGIDMEWRPSFGMVGKPRVSLLQLAVRDEVFLLDLPRLLEQAEVKGEKEKLPHFIQRLYSDATITKLGYGMSGDLSSLAATCSTLKGMDKQSQSVVDLLTIDKLLQKSSTDWKKGGLKVDVLSPEQSCEDGGLRQPEKGLSLLVQHVLGKPLDKTEQMSNWEKRPLREEQILYAASDAYCLLEVYEKLCKDPESFGLSSDLTESLVGKPSVKPRAKKQLNKQEVPSPSGQQCKGSDKETSCPPAPISPKEFSVVCDNMLQGLGRYLRCLGVDVRMLENEDDHRKAAEIARQEGRVILTSGLPYQTLRSHVGEGRCFSVNCSEKAKEQALQVLKHFNVHVTLADIFSRCQVCNCDKYLKVPKERMRQLVEDSRHSLGDSSTGCPTSRKEKPGGTCSAAQPTGTTPGQQLESTGPCGADVGLVGGTALQLAAIPSGVLEKAELTDFYCCTGCGKVFWEGSHFGRVVSQFQDILVTTGGEQRVYELS", "length": 873, "header": "tr|A0A8V1AIT1-1|A0A8V1AE11_CHICK Computationally mapped isoform of Exonuclease 3'-5' domain containing 3 OS=Gallus gallus OX=9031 GN=EXD3 PE=1 SV=1 CANONICAL=A0A8V1AE11-1" }, "locus": { "chromosome": "17", "start_pos": 1506551, "end_pos": 1335376, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068965.1", "url": "https://www.ensembl.org/id/ENSGALT00010068965.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042407.1", "url": "https://www.ensembl.org/id/ENSGALP00010042407.1" } ] } }, { "isoform_ac": "A0A8V1AIT6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE11/entry#A0A8V1AIT6-1", "sequence": { "sequence": "MSQEGNSGDRPAGQDPLLLLKTLQLLWTKKEMKKQLKEEIRRGFAGLEDPLAGLLDMLESNGDWKGKGHSLGYYISSELQLWMKEHPAVQQSGMKLKKLQARVFRILDQCPANLLDPLISIYQLHTADRNYLLGHVSHLYHRGDYKEAAILSIKLKLQPDQDVEKMCAPLLFQDKINLVEDYVAEYPELQCRLLEILDTWCEPDFNIRDMARQYQGLSRYKPDKLNRKMLSKLIFRLLDRFNVDPALCPNVINQRHLRTLNYLFYKRFVEKTMTQENWADHIQSTVGENRWLQGHLIQLLLRYCDLNTAARWAQRCSLPEEVLPSEVADELQKLEIQERVEEATKEENYKEVKKKDYYQLPIPRANIRLLQNWEEMMQCYEKVLKPGQIVGIDMEWRPSFGMVGKPRVSLLQLAVRDEVFLLDLPRLLEQAEVKGEKEKLPHFIQRLYSDATITKLGYGMSGDLSSLAATCSTLKGMDKQSQSVVDLLTIDKLLQKSSTDWKKGGLKVDVLSPEQSCEDGGLRQPEKGLSLLVQHVLGKPLDKTEQMSNWEKRPLREEQILYAASDAYCLLEVYEKLCKDPESFGLSSDLTESLVGKPSVKPRAKKQLNKQEVPSPSGQCKGSDKETSCPPAPISPKEFSVVCDNMLQGLGRYLRCLGVDVRMLENEDDHRKAAEIARQEGRVILTSGLPYQTLRSHVGEGRCFSVNCSEKAKEQALQVLKHFNVHVTLADIFSRCQVCNCDKYLKVPKERMRQLVEDSRHSLGDSSTGCPTSRKEKPGGTCSAAQPTGTTPGQQLESTGPCGADVGLVGGTALQLAAIPSGVLEKAELTDFYCCTGCGKVFWEGSHFGRVVSQFQDILVTTGGEQRVYELS", "length": 872, "header": "tr|A0A8V1AIT6-1|A0A8V1AE11_CHICK Computationally mapped isoform of Exonuclease 3'-5' domain containing 3 OS=Gallus gallus OX=9031 GN=EXD3 PE=1 SV=1 CANONICAL=A0A8V1AE11-1" }, "locus": { "chromosome": "17", "start_pos": 1521216, "end_pos": 1335376, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068970.1", "url": "https://www.ensembl.org/id/ENSGALT00010068970.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042412.1", "url": "https://www.ensembl.org/id/ENSGALP00010042412.1" } ] } }, { "isoform_ac": "A0A8V1AKL3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE11/entry#A0A8V1AKL3-1", "sequence": { "sequence": "MSQEGNSGDRPAGQDPLLLLKTLQLLWTKKEMKKLKEEIRRGFAGLEDPLAGLLDMLESNGDWKGKGHSLGYYISSELQLWMKEHPAVQQSGMKLKKLQARVFRILDQCPANLLDPLISIYQLHTADRNYLLGHVSHLYHRGDYKEAAILSIKLKLQPDQDVEKMCAPLLFQDKINLVEDYVAEYPELQCRLLEILDTWCEPDFNIRDMARQYQGLSRYKPDKLNRKMLSKLIFRLLDRFNVDPALCPNVINQRHLRTLNYLFYKRFVEKTMTQENWADHIQSTVGENRWLQGHLIQLLLRYCDLNTAARWAQRCSLPEEVLPSEVADELQKLEIQERVEEATKEENYKEVKKKDYYQLPIPRANIRLLQNWEEMMQCYEKVLKPGQIVGIDMEWRPSFGMVGKPRVSLLQLAVRDEVFLLDLPRLLEQAEVKGEKEKLPHFIQRLYSDATITKLGYGMSGDLSSLAATCSTLKGMDKQSQSVVDLLTIDKLLQKSSTDWKKGGLKVDVLSPEQSCEDGGLRQPEKGLSLLVQHVLGKPLDKTEQMSNWEKRPLREEQILYAASDAYCLLEVYEKLCKDPESFGLSSDLTESLVGKPSVKPRAKKQLNKQEVPSPSGQIARQEGRVILTSGLPYQTLRSHVGEGRCFSVNCSEKAKEQALQVLKHFNVHVTLADIFSRCQVSQQVRGHCIAQEQVCFLGCHHAFTTPDPCRPRAQCWRQAAGSPAGLKAVCEPSRPILTYGSSVITSALPPWRAPAVSGPSQFGQQWEAQGRGLGGRGSWPCPRLSSAPPLCTSSCHIRASCWVRIASRLTQNFPPVSWLRVMAQKCF", "length": 828, "header": "tr|A0A8V1AKL3-1|A0A8V1AE11_CHICK Computationally mapped isoform of Exonuclease 3'-5' domain containing 3 OS=Gallus gallus OX=9031 GN=EXD3 PE=1 SV=1 CANONICAL=A0A8V1AE11-1" }, "locus": { "chromosome": "17", "start_pos": 1521216, "end_pos": 1359210, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068968.1", "url": "https://www.ensembl.org/id/ENSGALT00010068968.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042410.1", "url": "https://www.ensembl.org/id/ENSGALP00010042410.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "nucleic acid binding", "id": "GO:0003676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AE11", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE11" } ], "pmid": "" }, { "name": "3'-5' exonuclease activity", "id": "GO:0008408", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008408", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AE11", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE11" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "nucleobase-containing compound metabolic process", "id": "GO:0006139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006139", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AE11", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE11" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 707, "end_pos": 709, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AE11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE11" }, { "id": "SM00474", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00474" } ], "ann_type": 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"url": "https://www.uniprot.org/uniprotkb/A0A8V1ADX1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLACCSSLECCHTDMRIQDCHFTLCSHLLKTPAWSCLLSACCPPSAAPTLGVALVPIWWSASVPCAAAAAVEKPCRPRQPRVRRTSSLDTIVGSYLLGQWPRDADGASASCMNDKATQTPVSWHDAEVGKASSSAHKRSASWGSTDHRREIAKLKQQLQRTKLNGRSGKEKEKSSPLQGDHAVLGSLRDSPSGFLSSSPVLRLSPCLHRSLEGLNQELEEVFVKEQGDEELLRILDVPDGHRAPAPAQRGSGDASLMLEPSSGSCSSLSLSPSPSVPLHLSPHTPVRLVAEELSSAVDEVQLDPKEKEEGSPSPVLAFASSPRPNHSYMFKREPPEGCEKVRAFEEASSSPDHTFQPSCPDKNKVHFNPTGSAFCPVSLVKPLFPNVGLLFRGFPASSSPATGTFTSCQPTAPTPFLGARKDAAVDNFSDASKSPSLNYEHWKRGQPEESVVFHSSLVV", "length": 459, "header": "tr|A0A8V1ADX1-1|A0A8V1ADX1_CHICK Isoform 1 of Family with sequence similarity 117 member A OS=Gallus gallus OX=9031 GN=FAM117A PE=4 SV=1 CANONICAL=A0A8V1ADX1-1" }, "isoforms": [ { "isoform_ac": "A0A1D5P795-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADX1/entry#A0A1D5P795-1", "sequence": { "sequence": "MLACCSSLECCHTDMRIQDCHFTLCSHLLKFQEAEGWCCVTEQLWFARQWQMASVPCAAAAAVEKPCRPRQPRVRRTSSLDTIVGSYLLGQWPRDADGASASCMNDKATQTPVSWHDAEVGKASSSAHKRSASWGSTDHRREIAKLKQQLQRTKLNGRSGKEKEKSSPLQGDHAVLGSLRDSPSGFLSSSPVLRLSPCLHRSLEGLNQELEEVFVKEQGDEELLRILDVPDGHRAPAPAQRGSGDASLMLEPSSGSCSSLSLSPSPSVPLHLSPHTPVRLVAEELSSAVDEVQLDPKEKEEGSPSPVLAFASSPRPNHSYMFKREPPEGCEKVRAFEEASSSPDHTFQPSCPDKNKVHFNPTGSAFCPVSLVKPLFPNVGLLFRGFPASSSPATGTFTSCQPTAPTPFLGARKDAAVDNFSDASKSPSLNYEHWKRGQPEESVVFHSSLVV", "length": 451, "header": "tr|A0A1D5P795-1|A0A1D5P795_CHICK Computationally mapped isoform of Family with sequence similarity 117 member A OS=Gallus gallus OX=9031 GN=FAM117A PE=4 SV=1 CANONICAL=A0A8V1ADX1-1" }, "locus": { "chromosome": "27", "start_pos": 2946072, "end_pos": 2922051, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065051.1", "url": "https://www.ensembl.org/id/ENSGALT00010065051.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039689.1", "url": "https://www.ensembl.org/id/ENSGALP00010039689.1" } ] } }, { "isoform_ac": "A0A8V1A8Z3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADX1/entry#A0A8V1A8Z3-1", "sequence": { "sequence": "MAGAAGTSCCRSGAGGLQPLRATVPFQLQQRRGASGDGGRAASVPCAAAAAVEKPCRPRQPRVRRTSSLDTIVGSYLLGQWPRDADGASASCMNDKATQTPVSWHDAEVGKASSSAHKRSASWGSTDHRREIAKLKQQLQRTKLNGRSGKEKEKSSPLQGDHAVLGSLRDSPSGFLSSSPVLRLSPCLHRSLEGLNQELEEVFVKEQGDEELLRILDVPDGHRAPAPAQRGSGDASLMLEPSSGSCSSLSLSPSPSVPLHLSPHTPVRLVAEELSSAVDEVQLDPKEKEEGSPSPVLAFASSPRPNHSYMFKREPPEGCEKVRAFEEASSSPDHTFQPSCPDKNKVHFNPTGSAFCPVSLVKPLFPNVGLLFRGFPASSSPATGTFTSCQPTAPTPFLGARKDAAVDNFSDASKSPSLNYEHWKRGQPEESVVFHSSLVV", "length": 440, "header": "tr|A0A8V1A8Z3-1|A0A8V1ADX1_CHICK Computationally mapped isoform of Family with sequence similarity 117 member A OS=Gallus gallus OX=9031 GN=FAM117A PE=4 SV=1 CANONICAL=A0A8V1ADX1-1" }, "locus": { "chromosome": "27", "start_pos": 2946072, "end_pos": 2929793, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065048.1", "url": "https://www.ensembl.org/id/ENSGALT00010065048.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039688.1", "url": "https://www.ensembl.org/id/ENSGALP00010039688.1" } ] } }, { "isoform_ac": "A0A8V1ABV4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADX1/entry#A0A8V1ABV4-1", "sequence": { "sequence": "MDVCFWIFLSAGACLTELHGAQLSFHIGWVRTGRTWAPICAVPASVPCAAAAAVEKPCRPRQPRVRRTSSLDTIVGSYLLGQWPRDADGASASCMNDKATQTPVSWHDAEVGKASSSAHKRSASWGSTDHRREIAKLKQQLQRTKLNGRSGKEKEKSSPLQGDHAVLGSLRDSPSGFLSSSPVLRLSPCLHRSLEGLNQELEEVFVKEQGDEELLRILDVPDGHRAPAPAQRGSGDASLMLEPSSGSCSSLSLSPSPSVPLHLSPHTPVRLVAEELSSAVDEVQLDPKEKEEGSPSPVLAFASSPRPNHSYMFKREPPEGCEKVRAFEEASSSPDHTFQPSCPDKNKVHFNPTGSAFCPVSLVKPLFPNVGLLFRGFPASSSPATGTFTSCQPTAPTPFLGARKDAAVDNFSDASKSPSLNYEHWKRGQPEESVVFHSSLVV", "length": 442, "header": "tr|A0A8V1ABV4-1|A0A8V1ABV4_CHICK Computationally mapped isoform of Family with sequence similarity 117 member A OS=Gallus gallus OX=9031 GN=FAM117A PE=4 SV=1 CANONICAL=A0A8V1ADX1-1" }, "locus": { "chromosome": "27", "start_pos": 2946072, "end_pos": 2933856, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065047.1", "url": "https://www.ensembl.org/id/ENSGALT00010065047.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039687.1", "url": "https://www.ensembl.org/id/ENSGALP00010039687.1" } ] } }, { "isoform_ac": "A0A8V1ADX1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADX1/entry#A0A8V1ADX1-1", "sequence": { "sequence": "MLACCSSLECCHTDMRIQDCHFTLCSHLLKTPAWSCLLSACCPPSAAPTLGVALVPIWWSASVPCAAAAAVEKPCRPRQPRVRRTSSLDTIVGSYLLGQWPRDADGASASCMNDKATQTPVSWHDAEVGKASSSAHKRSASWGSTDHRREIAKLKQQLQRTKLNGRSGKEKEKSSPLQGDHAVLGSLRDSPSGFLSSSPVLRLSPCLHRSLEGLNQELEEVFVKEQGDEELLRILDVPDGHRAPAPAQRGSGDASLMLEPSSGSCSSLSLSPSPSVPLHLSPHTPVRLVAEELSSAVDEVQLDPKEKEEGSPSPVLAFASSPRPNHSYMFKREPPEGCEKVRAFEEASSSPDHTFQPSCPDKNKVHFNPTGSAFCPVSLVKPLFPNVGLLFRGFPASSSPATGTFTSCQPTAPTPFLGARKDAAVDNFSDASKSPSLNYEHWKRGQPEESVVFHSSLVV", "length": 459, "header": "tr|A0A8V1ADX1-1|A0A8V1ADX1_CHICK Isoform 1 of Family with sequence similarity 117 member A OS=Gallus gallus OX=9031 GN=FAM117A PE=4 SV=1 CANONICAL=A0A8V1ADX1-1" }, "locus": { "chromosome": "27", "start_pos": 2946072, "end_pos": 2922051, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065053.1", "url": "https://www.ensembl.org/id/ENSGALT00010065053.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039690.1", "url": "https://www.ensembl.org/id/ENSGALP00010039690.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 325, "end_pos": 327, "annotation": "n_glycosylation_sequon" }, { "start_pos": 427, "end_pos": 429, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": 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{ "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1ADX8-1", "uniprot_ac": "A0A8V1ADX8", "uniprot_id": "A0A8V1ADX8_CHICK", "mass": { "chemical_mass": 50686.0, "monoisotopic_mass": 50686.0 }, "refseq": {}, "gene_names": [ { "name": "LRMPL", "type": "recommended", "evidence": [ { "id": "A0A8V1ADX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADX8" } ] } ], "protein_names": [ { "name": "Lymphoid-restricted membrane protein-like", "type": "recommended", "evidence": [ { "id": "A0A8V1ADX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADX8/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADX8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADX8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LRMPL", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADX8", "locus": {} } ], "crossref": [ { "id": "A0A8V1ADX8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1ADX8", "database": "AlphaFoldDB", "categories": [] }, { "id": "425540", "url": "https://www.ncbi.nlm.nih.gov/gene/425540", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR008677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:425540", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:425540", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTHR15352", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15352", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15352:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15352:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05781", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05781", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1A8Z8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8Z8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A8Z8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8Z8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ABV9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABV9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ABV9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABV9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ADX8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADX8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ADX8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADX8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKPRVDTSLGVGKEVWGRAQGRAAWRQRRGCRQSPPQSREQQAEPARLLAAPDEGRMSSPQEHLDRVLAGSKESMGSISEEPGTELAFCTGDGDGIEEDEETPEELLLSFPSELSVLERLGLHSTNLTEQDVEAAFAHLALAFRCDMFTLQQRAQVEKRAQDAAEENIQEELGQCQTFLERLSTSCMDVSCKEVLEQLQCSLAVLAAAIKRATSAAEKLGAVHQEARMSRAAEVMVQHVDNLKRHHLREHAELEEMKCLIQQNSRNRQLAETQDDAEQQLRPHPLMRGFQQGLTGRRLLSSSSLNSSLLPLQLMRHLHAAESASLSSQSSSCQLLAWMAEKPWLVGPRVPNARPAPRVSHFSLPRSKLEPPSQGSVVSKGLVVEAGGKELESSAGGEELGQLRMMSKESPVELWQPWLFISQPYWVVFCLLLLSVALLLLLHLLELQWLQPSASPKA", "length": 457, "header": "tr|A0A8V1ADX8-1|A0A8V1ADX8_CHICK Isoform 1 of Lymphoid-restricted membrane protein-like OS=Gallus gallus OX=9031 GN=LRMPL PE=4 SV=1 CANONICAL=A0A8V1ADX8-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A8Z8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADX8/entry#A0A8V1A8Z8-1", "sequence": { "sequence": "MKPRVDTSLGVGKEVWGRAQGRAAWRQRRGCRQSPPQSREQQAEPARLLAAPDEGRMSSPQEHLDRVLAGSKESMGSISEHEEGVWSESAPSQEPGTELAFCTGDGDGIEEDEETPEELLLSFPSELSVLERLGLHSTNLTEQDVEAAFAHLALAFRCDMFTLQQRAQVEKRAQDAAEENIQEELGQCQTFLERLSTSCMDVSCKEVLEQLQCSLAVLAAAIKRATSAAEKLGAVHQEARMSRAAEVMVQHVDNLKRHHLREHAELEEMKCLIQQNSRNRQLAETQDDAEQQLRPHPLMRGFQQASARRRVSIAVIPKQLVPASGVDGRETLAGRPKGAQRQTSTQRSKLEPPSQGSVVSKGLVVEAGGKELESSAGGEELGQLRMMSKESPVELWQPWLFISQPYWVVFCLLLLSVALLLLLHLLELQWLQPSASPKA", "length": 439, "header": "tr|A0A8V1A8Z8-1|A0A8V1ADX8_CHICK Computationally mapped isoform of Lymphoid-restricted membrane protein-like OS=Gallus gallus OX=9031 GN=LRMPL PE=4 SV=1 CANONICAL=A0A8V1ADX8-1" }, "locus": { "chromosome": "26", "start_pos": 65113, "end_pos": 60109, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065085.1", "url": "https://www.ensembl.org/id/ENSGALT00010065085.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039693.1", "url": "https://www.ensembl.org/id/ENSGALP00010039693.1" } ] } }, { "isoform_ac": "A0A8V1ABV9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADX8/entry#A0A8V1ABV9-1", "sequence": { "sequence": "MKPRVDTSLGVGKEVWGRAQGRAAWRQRRGCRQSPPQSREQQAEPARLLAAPDEVLQPLPASQQLLLDDGDILNPVRGRMSSPQEHLDRVLAGSKESMGSISEEPGTELAFCTGDGDGIEEDEETPEELLLSFPSELSVLERLGLHSTNLTEQDVEAAFAHLALAFRCDMFTLQQRAQVEKRAQDAAEENIQEELGQCQTFLERLSTSCMDVSCKEVLEQLQCSLAVLAAAIKRATSAAEKLGAVHQEARMSRAAEVMVQHVDNLKRHHLREHAELEEMKCLIQQNSRNRQLAETQDDAEQQLRPHPLMRGFQQASARRRVSIAVIPKQLVPASGVDGRETLAGRPKGAQRQTSTQRSKLEPPSQGSVVSKGLVVEAGGKELESSAGGEELGQLRMMSKESPVELWQPWLFISQPYWVVFCLLLLSVALLLLLHLLELQWLQPSASPKA", "length": 449, "header": "tr|A0A8V1ABV9-1|A0A8V1ABV9_CHICK Computationally mapped isoform of Lymphoid-restricted membrane protein-like OS=Gallus gallus OX=9031 GN=LRMPL PE=4 SV=1 CANONICAL=A0A8V1ADX8-1" }, "locus": { "chromosome": "26", "start_pos": 65113, "end_pos": 60109, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065080.1", "url": "https://www.ensembl.org/id/ENSGALT00010065080.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039692.1", "url": "https://www.ensembl.org/id/ENSGALP00010039692.1" } ] } }, { "isoform_ac": "A0A8V1ADX8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADX8/entry#A0A8V1ADX8-1", "sequence": { "sequence": "MKPRVDTSLGVGKEVWGRAQGRAAWRQRRGCRQSPPQSREQQAEPARLLAAPDEGRMSSPQEHLDRVLAGSKESMGSISEEPGTELAFCTGDGDGIEEDEETPEELLLSFPSELSVLERLGLHSTNLTEQDVEAAFAHLALAFRCDMFTLQQRAQVEKRAQDAAEENIQEELGQCQTFLERLSTSCMDVSCKEVLEQLQCSLAVLAAAIKRATSAAEKLGAVHQEARMSRAAEVMVQHVDNLKRHHLREHAELEEMKCLIQQNSRNRQLAETQDDAEQQLRPHPLMRGFQQGLTGRRLLSSSSLNSSLLPLQLMRHLHAAESASLSSQSSSCQLLAWMAEKPWLVGPRVPNARPAPRVSHFSLPRSKLEPPSQGSVVSKGLVVEAGGKELESSAGGEELGQLRMMSKESPVELWQPWLFISQPYWVVFCLLLLSVALLLLLHLLELQWLQPSASPKA", "length": 457, "header": "tr|A0A8V1ADX8-1|A0A8V1ADX8_CHICK Isoform 1 of Lymphoid-restricted membrane protein-like OS=Gallus gallus OX=9031 GN=LRMPL PE=4 SV=1 CANONICAL=A0A8V1ADX8-1" }, "locus": { "chromosome": "26", "start_pos": 65113, "end_pos": 60109, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065092.1", "url": "https://www.ensembl.org/id/ENSGALT00010065092.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039695.1", "url": "https://www.ensembl.org/id/ENSGALP00010039695.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:425540", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:425540", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADX8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADX8" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADX8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADX8" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADX8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADX8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 126, "end_pos": 128, "annotation": "n_glycosylation_sequon" }, { "start_pos": 305, "end_pos": 307, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 126, "end_pos": 128 }, { "start_pos": 305, "end_pos": 307 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AE14-1", "uniprot_ac": "A0A8V1AE14", "uniprot_id": "A0A8V1AE14_CHICK", "mass": { "chemical_mass": 45462.0, "monoisotopic_mass": 45462.0 }, "refseq": {}, "gene_names": [ { "name": "TULP1", "type": "recommended", "evidence": [ { "id": "A0A8V1AE14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE14" } ] } ], "protein_names": [ { "name": "Tubby-like protein", "type": "recommended", "evidence": [ { "id": "A0A8V1AE14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE14/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AE14", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE14" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TULP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE14", "locus": { "chromosome": "26", "start_pos": 105849, "end_pos": 110524, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010026885", "url": "https://www.ensembl.org/id/ENSGALG00010026885" } ] } } ], "crossref": [ { "id": "A0A8V1AE14", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AE14", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR000007", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000007", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018066", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018066", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025659", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025659", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A934", "url": "https://www.orthodb.org/?gene=A0A8V1A934", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AE14", "url": "https://www.orthodb.org/?gene=A0A8V1AE14", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16517", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16517", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16517:SF12", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16517:SF12", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01167", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01167", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1A934", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A934", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A934-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A934-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AE14", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE14", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AE14-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE14-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEIKDPPKKLKKKLTKEPPSGEKKLKAKGDKSNADSKAKSTKSTKKEPTSMFQVNGEKKEKKSKKKAATGSDEEDDSDASTKPIRSGKKNPASLFQTGGDPPRERKTRKKAPKTAESEEETLETQQKNSNKKGKGKKSKKKEERPLSPVIEVDNLEKFVLSPAPQGVTIKCRVTRDKRGMDRGLYPTYYLHLDNDKKVFLLAGRKRKKSKTSNYLISIDPTDLSRGGENFIGKLRSNLMGTKFTVFDNGANPDRASADWSNVRQELSAVVYETNVLGFKGPRKMTVIIPGMNSDNERVPIRPRNDNDGLLMRWQNKNMDNIIELHNKAPVWNDETQSYVLNFHGRVTHASVKNFQIVHGSDPDYIVMQFGRVADDAFTMDYNYPLCAVQAFAIALSSFDGKLACE", "length": 405, "header": "tr|A0A8V1AE14-1|A0A8V1AE14_CHICK Isoform 1 of Tubby-like protein OS=Gallus gallus OX=9031 GN=TULP1 PE=3 SV=1 CANONICAL=A0A8V1AE14-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A934-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE14/entry#A0A8V1A934-1", "sequence": { "sequence": "MFQVNGEKKEKKSKKKAATGSDEEDDSDASTKPIRSGKKNPASLFQTGGDPPRERKTRKKAPKTAESEEETLETQQKNSNKKGKGKKSKKKEERPLSPVIEVDNLEKFVLSPAPQGVTIKCRVTRDKRGMDRGLYPTYYLHLDNDKKVFLLAGRKRKKSKTSNYLISIDPTDLSRGGENFIGKLRSNLMGTKFTVFDNGANPDRASADWSNVRQELSAVVYETNVLGFKGPRKMTVIIPGMNSDNERVPIRPRNDNDGLLMRWQNKNMDNIIELHNKAPVWNDETQSYVLNFHGRVTHASVKNFQIVHGSDRKRRDTVRGALG", "length": 323, "header": "tr|A0A8V1A934-1|A0A8V1AE14_CHICK Computationally mapped isoform of Tubby-like protein OS=Gallus gallus OX=9031 GN=TULP1 PE=3 SV=1 CANONICAL=A0A8V1AE14-1" }, "locus": { "chromosome": "26", "start_pos": 109423, "end_pos": 107014, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065246.1", "url": "https://www.ensembl.org/id/ENSGALT00010065246.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039728.1", "url": "https://www.ensembl.org/id/ENSGALP00010039728.1" } ] } }, { "isoform_ac": "A0A8V1AE14-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE14/entry#A0A8V1AE14-1", "sequence": { "sequence": "MEIKDPPKKLKKKLTKEPPSGEKKLKAKGDKSNADSKAKSTKSTKKEPTSMFQVNGEKKEKKSKKKAATGSDEEDDSDASTKPIRSGKKNPASLFQTGGDPPRERKTRKKAPKTAESEEETLETQQKNSNKKGKGKKSKKKEERPLSPVIEVDNLEKFVLSPAPQGVTIKCRVTRDKRGMDRGLYPTYYLHLDNDKKVFLLAGRKRKKSKTSNYLISIDPTDLSRGGENFIGKLRSNLMGTKFTVFDNGANPDRASADWSNVRQELSAVVYETNVLGFKGPRKMTVIIPGMNSDNERVPIRPRNDNDGLLMRWQNKNMDNIIELHNKAPVWNDETQSYVLNFHGRVTHASVKNFQIVHGSDPDYIVMQFGRVADDAFTMDYNYPLCAVQAFAIALSSFDGKLACE", "length": 405, "header": "tr|A0A8V1AE14-1|A0A8V1AE14_CHICK Isoform 1 of Tubby-like protein OS=Gallus gallus OX=9031 GN=TULP1 PE=3 SV=1 CANONICAL=A0A8V1AE14-1" }, "locus": { "chromosome": "26", "start_pos": 109656, "end_pos": 106109, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065250.1", "url": "https://www.ensembl.org/id/ENSGALT00010065250.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039730.1", "url": "https://www.ensembl.org/id/ENSGALP00010039730.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "phosphatidylinositol-4,5-bisphosphate binding", "id": "GO:0005546", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005546", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AE14", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE14" } ], "pmid": "" }, { "name": "actin filament binding", "id": "GO:0051015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051015", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AE14", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE14" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AE14", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE14" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AE14", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE14" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AE14", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE14" } ], "pmid": "" }, { "name": "cilium", "id": "GO:0005929", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005929", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AE14", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE14" } ], "pmid": "" }, { "name": "axon terminus", "id": "GO:0043679", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043679", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AE14", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE14" } ], "pmid": "" }, { "name": "photoreceptor inner segment", "id": "GO:0001917", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001917", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AE14", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE14" } ], "pmid": "" }, { "name": "photoreceptor outer segment", "id": "GO:0001750", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001750", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AE14", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE14" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "dendrite development", "id": "GO:0016358", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016358", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AE14", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE14" } ], "pmid": "" }, { "name": "photoreceptor cell maintenance", "id": "GO:0045494", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045494", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AE14", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE14" } ], "pmid": "" }, { "name": "positive regulation of phagocytosis", "id": "GO:0050766", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050766", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AE14", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE14" } ], "pmid": "" }, { "name": "protein localization to cilium", "id": "GO:0061512", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061512", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AE14", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE14" } ], "pmid": "" }, { "name": "detection of light stimulus involved in visual perception", "id": "GO:0050908", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050908", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AE14", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE14" } ], "pmid": "" }, { "name": "eye photoreceptor cell development", "id": "GO:0042462", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042462", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AE14", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE14" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AE14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE14" }, { "id": "PF01167", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01167" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Tubby C-terminal", "eco_id": "ECO_0000259", "start_pos": 160, "end_pos": 399, "start_aa": "Leu", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AEB8-1", "uniprot_ac": "A0A8V1AEB8", "uniprot_id": "A0A8V1AEB8_CHICK", "mass": { "chemical_mass": 16383.0, "monoisotopic_mass": 16383.0 }, "refseq": { "ac": "XP_040546817", "name": "scale keratin-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040546817" }, "gene_names": [ { "name": "LOC431314", "type": "recommended", "evidence": [ { "id": "A0A8V1AEB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEB8" } ] }, { "name": "LOC431314", "type": "synonym", "evidence": [ { "id": "XP_040546817", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040546817" } ] } ], "protein_names": [ { "name": "Keratin", "type": "recommended", "evidence": [ { "id": "A0A8V1AEB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEB8/entry#names_and_taxonomy" } ] }, { "name": "scale keratin-like", "type": "synonym", "evidence": [ { "id": "XP_040546817", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040546817" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040546817", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040546817" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEB8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEB8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC431314", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEB8", "locus": {} } ], "crossref": [ { "id": "431314", "url": "https://www.ncbi.nlm.nih.gov/gene/431314", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003461", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003461", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:431314", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:431314", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GNEPCFR", "url": "https://omabrowser.org/oma/group/GNEPCFR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A965", "url": "https://www.orthodb.org/?gene=A0A8V1A965", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AEB8", "url": "https://www.orthodb.org/?gene=A0A8V1AEB8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31203", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31203", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31203:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31203:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02422", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02422", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040546817", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040546817", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1A965", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A965", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A965-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A965-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AEB8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEB8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AEB8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEB8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSCYDLCSTTTGGISCPQPIADSCNEPCVRQCPDSTTVIQPPPVAITFPGPILSSFPQQAVVGSSGAPVLGGSGGSSLGYGGLYGYGGSSLGYGGLYGLGSYGGYGGYGGLYGASSLGYGGLYGGSCLGYGGLYGYGRSYGSSYCSPYSYRYSRYRRGSCGPC", "length": 163, "header": "tr|A0A8V1AEB8-1|A0A8V1AEB8_CHICK Isoform 1 of Keratin OS=Gallus gallus OX=9031 GN=LOC431314 PE=3 SV=1 CANONICAL=A0A8V1AEB8-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A965-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEB8/entry#A0A8V1A965-1", "sequence": { "sequence": "MSCYDLCSTTTGGISCPQPIADSCNEPCVRQCPDSTTVIQPPPVAITFPGPILSSFPQQAVVGSSGAPVLGGSGGSSLGYGGLYGLGSYGGYGGYGGLYGASSLGYGGLYGGSCLGYGGLYGYGRSYGSSYCSPYSYRYSRYRRGSCGPC", "length": 150, "header": "tr|A0A8V1A965-1|A0A8V1AEB8_CHICK Computationally mapped isoform of Keratin OS=Gallus gallus OX=9031 GN=LOC431314 PE=3 SV=1 CANONICAL=A0A8V1AEB8-1" }, "locus": { "chromosome": "25", "start_pos": 1405605, "end_pos": 1405117, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069062.1", "url": "https://www.ensembl.org/id/ENSGALT00010069062.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042504.1", "url": "https://www.ensembl.org/id/ENSGALP00010042504.1" } ] } }, { "isoform_ac": "A0A8V1AEB8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEB8/entry#A0A8V1AEB8-1", "sequence": { "sequence": "MSCYDLCSTTTGGISCPQPIADSCNEPCVRQCPDSTTVIQPPPVAITFPGPILSSFPQQAVVGSSGAPVLGGSGGSSLGYGGLYGYGGSSLGYGGLYGLGSYGGYGGYGGLYGASSLGYGGLYGGSCLGYGGLYGYGRSYGSSYCSPYSYRYSRYRRGSCGPC", "length": 163, "header": "tr|A0A8V1AEB8-1|A0A8V1AEB8_CHICK Isoform 1 of Keratin OS=Gallus gallus OX=9031 GN=LOC431314 PE=3 SV=1 CANONICAL=A0A8V1AEB8-1" }, "locus": { "chromosome": "25", "start_pos": 1405605, "end_pos": 1405117, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069064.1", "url": "https://www.ensembl.org/id/ENSGALT00010069064.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042506.1", "url": "https://www.ensembl.org/id/ENSGALP00010042506.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:431314", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:431314", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "structural constituent of cytoskeleton", "id": "GO:0005200", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005200", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEB8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEB8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "intermediate filament", "id": "GO:0005882", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005882", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEB8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEB8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": 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0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1ABZ0-1", "uniprot_ac": "A0A8V1ABZ0", "uniprot_id": "A0A8V1ABZ0_CHICK", "mass": { "chemical_mass": 43430.0, "monoisotopic_mass": 43430.0 }, "refseq": {}, "gene_names": [ { "name": "TWF2", "type": "recommended", "evidence": [ { "id": "A0A8V1ABZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABZ0" } ] } ], "protein_names": [ { "name": "Twinfilin actin binding protein 2", "type": "synonym", "evidence": [ { "id": "A0A8V1ABZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABZ0/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": 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"https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11285", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR002108", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002108", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028458", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028458", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029006", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029006", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A992", "url": "https://www.orthodb.org/?gene=A0A8V1A992", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ABZ0", "url": "https://www.orthodb.org/?gene=A0A8V1ABZ0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AGN6", "url": "https://www.orthodb.org/?gene=A0A8V1AGN6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AGP1", "url": "https://www.orthodb.org/?gene=A0A8V1AGP1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13759", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13759", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13759:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13759:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00241", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00241", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1A992", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A992", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A992-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A992-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ABZ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABZ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ABZ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABZ0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGN6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGN6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGN6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGN6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGP1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGP1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGP1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTHQTGIHATTELRDFFAKARNGSVRLIKVIIEEEQLVLGAHKELARRWDVDYDAFVLPLLDEQQPCYVLYRLDSQNAQGYEWLFISWSPDNSPVRLKMLYAATRATVKKEFGGGHIKDEMFGTVKEDVSLSGYQKHVSSCSAPAPLTAAEQELQQIRINEGEVAQDACSQDSSTEMMVGGCCCCPSLVEYPSPEEVKTEISVESKHQTLQGLAFPLQLDAQQAIQALKQKKINYIQLKLDLERETIDLVHTSPTDISDLPKRIPQDSARYHFFLYKHSHEGDYLESVVFIYSMPGYKCSIKERMLYSSCKSRLLDTVEQEFCLEIAKKIEIDDGAELTAEFLYDEVHPKQHAFKQAFAKPKGPVGKRGQKRLIKGPGENGEDS", "length": 384, "header": "tr|A0A8V1ABZ0-1|A0A8V1ABZ0_CHICK Isoform 1 of Twinfilin actin binding protein 2 OS=Gallus gallus OX=9031 GN=TWF2 PE=1 SV=1 CANONICAL=A0A8V1ABZ0-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A992-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABZ0/entry#A0A8V1A992-1", "sequence": { "sequence": "MGFLLREGKGNENLPAAGVCSVSCCRAGFEEPIPISTTELRDFFAKARNGSVRLIKVIIEEEQLVLGAHKELARRWDVDYDAFVLPLLDEQQPCYVLYRLDSQNAQGYEWLFISWSPDNSPVRLKMLYAATRATVKKEFGGGHIKDEMFGTVKEDVSLSGYQKHVSSCSAPAPLTAAEQELQQIRINEVKTEISVESKHQTLQGLAFPLQLDAQQAIQALKQKKINYIQLKLDLERETIDLVHTSPTDISDLPKRIPQDSARYHFFLYKHSHEGDYLESVVFIYSMPGYKCSIKERMLYSSCKSRLLDTVEQEFCLEIAKKIEIDDGAELTAEFLYDEVHPKQHAFKQAFAKPKGPVGKRGQKRLIKGPGENGEDS", "length": 376, "header": "tr|A0A8V1A992-1|A0A8V1ABZ0_CHICK Computationally mapped isoform of Twinfilin actin binding protein 2 OS=Gallus gallus OX=9031 GN=TWF2 PE=1 SV=1 CANONICAL=A0A8V1ABZ0-1" }, "locus": { "chromosome": "12", "start_pos": 3145872, "end_pos": 3131555, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066513.1", "url": "https://www.ensembl.org/id/ENSGALT00010066513.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040741.1", "url": "https://www.ensembl.org/id/ENSGALP00010040741.1" } ] } }, { "isoform_ac": "A0A8V1ABZ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABZ0/entry#A0A8V1ABZ0-1", "sequence": { "sequence": "MTHQTGIHATTELRDFFAKARNGSVRLIKVIIEEEQLVLGAHKELARRWDVDYDAFVLPLLDEQQPCYVLYRLDSQNAQGYEWLFISWSPDNSPVRLKMLYAATRATVKKEFGGGHIKDEMFGTVKEDVSLSGYQKHVSSCSAPAPLTAAEQELQQIRINEGEVAQDACSQDSSTEMMVGGCCCCPSLVEYPSPEEVKTEISVESKHQTLQGLAFPLQLDAQQAIQALKQKKINYIQLKLDLERETIDLVHTSPTDISDLPKRIPQDSARYHFFLYKHSHEGDYLESVVFIYSMPGYKCSIKERMLYSSCKSRLLDTVEQEFCLEIAKKIEIDDGAELTAEFLYDEVHPKQHAFKQAFAKPKGPVGKRGQKRLIKGPGENGEDS", "length": 384, "header": "tr|A0A8V1ABZ0-1|A0A8V1ABZ0_CHICK Isoform 1 of Twinfilin actin binding protein 2 OS=Gallus gallus OX=9031 GN=TWF2 PE=1 SV=1 CANONICAL=A0A8V1ABZ0-1" }, "locus": { "chromosome": "12", "start_pos": 3148008, "end_pos": 3131555, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066517.1", "url": "https://www.ensembl.org/id/ENSGALT00010066517.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040743.1", "url": "https://www.ensembl.org/id/ENSGALP00010040743.1" } ] } }, { "isoform_ac": "A0A8V1AGN6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABZ0/entry#A0A8V1AGN6-1", "sequence": { "sequence": "MFLVLSATTELRDFFAKARNGSVRLIKVIIEEEQLVLGAHKELARRWDVDYDAFVLPLLDEQQPCYVLYRLDSQNAQGYEWLFISWSPDNSPVRLKMLYAATRATVKKEFGGGHIKDEMFGTVKEDVSLSGYQKHVSSCSAPAPLTAAEQELQQIRINEGEVAQVKTEISVESKHQTLQGLAFPLQLDAQQAIQALKQKKINYIQLKLDLERETIDLVHTSPTDISDLPKRIPQDSARYHFFLYKHSHEGDYLESVVFIYSMPGYKCSIKERMLYSSCKSRLLDTVEQEFCLEIAKKIEIDDGAELTAEFLYDEVHPKQHAFKQAFAKPKGPVGKRGQKRLIKGPGENGEDS", "length": 352, "header": "tr|A0A8V1AGN6-1|A0A8V1ABZ0_CHICK Computationally mapped isoform of Twinfilin actin binding protein 2 OS=Gallus gallus OX=9031 GN=TWF2 PE=1 SV=1 CANONICAL=A0A8V1ABZ0-1" }, "locus": { "chromosome": "12", "start_pos": 3142135, "end_pos": 3131555, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066512.1", "url": "https://www.ensembl.org/id/ENSGALT00010066512.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040740.1", "url": "https://www.ensembl.org/id/ENSGALP00010040740.1" } ] } }, { "isoform_ac": "A0A8V1AGP1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABZ0/entry#A0A8V1AGP1-1", "sequence": { "sequence": "MTHQTGIHATTELRDFFAKARNGSVRLIKVIIEEEQLVLGAHKELARRWDVDYDAFVLPLLDEQQPCYVLYRLDSQNAQGYEWLFISWSPDNSPVRLKMLYAATRATVKKEFGGGHIKDEMFGTVKEDVSLSGYQKHVSSCSAPAPLTAAEQELQQIRINEGEVAQDACSQDSSTEMVKTEISVESKHQTLQGLAFPLQLDAQQAIQALKQKKINYIQLKLDLERETIDLVHTSPTDISDLPKRIPQDSARYHFFLYKHSHEGDYLESVVFIYSMPGYKCSIKERMLYSSCKSRLLDTVEQEFCLEIAKKIEIDDGAELTAEFLYDEVHPKQHAFKQAFAKPKGPVGKRGQKRLIKGPGENGEDS", "length": 365, "header": "tr|A0A8V1AGP1-1|A0A8V1ABZ0_CHICK Computationally mapped isoform of Twinfilin actin binding protein 2 OS=Gallus gallus OX=9031 GN=TWF2 PE=1 SV=1 CANONICAL=A0A8V1ABZ0-1" }, "locus": { "chromosome": "12", "start_pos": 3148008, "end_pos": 3131555, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066520.1", "url": "https://www.ensembl.org/id/ENSGALT00010066520.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040745.1", "url": "https://www.ensembl.org/id/ENSGALP00010040745.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABZ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABZ0" } ], "pmid": "" }, { "name": "actin monomer binding", "id": "GO:0003785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003785", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABZ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABZ0" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABZ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABZ0" } ], "pmid": "" }, { "name": "phosphatidylinositol-4,5-bisphosphate binding", "id": "GO:0005546", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005546", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABZ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABZ0" } ], "pmid": "" }, { "name": "actin filament binding", "id": "GO:0051015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051015", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABZ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABZ0" } ], "pmid": "" }, { "name": "protein kinase C binding", "id": "GO:0005080", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005080", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABZ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABZ0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 9, "go_terms": [ { "name": "cytoskeleton", "id": "GO:0005856", "url": 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"https://www.uniprot.org/uniprotkb/A0A8V1A9G3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A9G3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9G3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AC69", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC69", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AC69-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC69-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLHLLLPRLLERSHPGAVKCNESPQNAMNHPETRTVPSPLSSLAPRRGSWRPQRCRPHVFLSPCRAARRAARCQRFWEALVCKKEQRQNSSEEDRVPQRSPRGDFSTDAPGAAPRALLPRSALPQIAKPAASRHRPERFAPTDLALLMENETLNSISRDVRGAAGCRGSSCRELSEGQYVLCRWTDGLYYLGKIKRVSGSKQSCLVTFEDNSKYWVLWKDIQHAGVPGEEPKCNICLEKTSGPRNEILICGKCGLGYHQQCHVPVASSDEGPLGTPWFCRRCIFALAVRKGGALKKGAIAKTLQAVKMVLSYNPDLLEWDSPHRTNQQQCYCYCGGPGEWYLKMLQCYRCRQWFHEACTQCLSDPMMFGDRFYVFFCSVCNQGPEYIKRLPLRWVDVVHLALYNLGVQSKKKYFDFEEILAFVNHHWDPLQLGKLTGTPVSERGPHLLNALNSYKSRFLCGKEIKKKKCIFRLRIRVPPNPPSKVLPEKAPGEGSTCELKRRGKSRYVHKDSLLPGQLQQQKRRAVRWKRAKFLLEDAIPSSDFTSAWSTNHHLASIFDFTLDEIQSLKSASSGQTFLSDVDSTDAVSTSGSATTSLSCESSRRTVGSRKRKQTVLTPPSARPKRGGGAAGRQPAVGSPQGSEVTCGPERPDDGIDSHTFESISEDDSSLSHLKSSISSYFGAAGRLVCGEKYQVLARRVTLEGKVQYLVEWEGTTPY", "length": 718, "header": "tr|A0A8V1AC69-1|A0A8V1AC69_CHICK Isoform 1 of PHD finger protein 19 OS=Gallus gallus OX=9031 GN=PHF19 PE=3 SV=1 CANONICAL=A0A8V1AC69-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A9G3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC69/entry#A0A8V1A9G3-1", "sequence": { "sequence": "MENETLNSISRDVRGAAGCRGSSCRELSEGQYVLCRWTDGLYYLGKIKRVSGSKQSCLVTFEDNSKYWVLWKDIQHAGVPGEEPKCNICLEKTSGPRNEILICGKCGLGYHQQCHVPVASSDEGPLGTPWFCRRCIFALAVRKGGALKKGAIAKTLQAVKMVLSYNPDLLEWDSPHRTNQQQCYCYCGGPGEWYLKMLQCYRCRQWFHEACTQCLSDPMMFGDRFYVFFCSVCNQGPEYIKRLPLRWVDVVHLALYNLGVQSKKKYFDFEEILAFVNHHWDPLQLGKLTGTPVSERGPHLLNALNSYKSRFLCGKEIKKKKCIFRLRIRVPPNPPSKVLPEKAPGEGSTCELKRRGKSRYVHKDSLLPGQLQQQKRRAVRWKRAKFLLEDAIPSSDFTSAWSTNHHLASIFDFTLDEIQSLKSASSGQTFLSDVDSTDAVSTSGSATTSLSCESSRRTVGSRKRKQTVLTPPSARPKRGGGAAGRQPAVGSPQGSEVTCGPERPDDGIDSHTFESISEDDSSLSHLKSSISSYFGAAGRLVCGEKYQVLARRVTLEGKVQYLVEWEGTTPY", "length": 571, "header": "tr|A0A8V1A9G3-1|A0A8V1AC69_CHICK Computationally mapped isoform of PHD finger protein 19 OS=Gallus gallus OX=9031 GN=PHF19 PE=3 SV=1 CANONICAL=A0A8V1AC69-1" }, "locus": { "chromosome": "17", "start_pos": 8900826, "end_pos": 8896943, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066678.1", "url": "https://www.ensembl.org/id/ENSGALT00010066678.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040823.1", "url": "https://www.ensembl.org/id/ENSGALP00010040823.1" } ] } }, { "isoform_ac": "A0A8V1AC69-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC69/entry#A0A8V1AC69-1", "sequence": { "sequence": "MLHLLLPRLLERSHPGAVKCNESPQNAMNHPETRTVPSPLSSLAPRRGSWRPQRCRPHVFLSPCRAARRAARCQRFWEALVCKKEQRQNSSEEDRVPQRSPRGDFSTDAPGAAPRALLPRSALPQIAKPAASRHRPERFAPTDLALLMENETLNSISRDVRGAAGCRGSSCRELSEGQYVLCRWTDGLYYLGKIKRVSGSKQSCLVTFEDNSKYWVLWKDIQHAGVPGEEPKCNICLEKTSGPRNEILICGKCGLGYHQQCHVPVASSDEGPLGTPWFCRRCIFALAVRKGGALKKGAIAKTLQAVKMVLSYNPDLLEWDSPHRTNQQQCYCYCGGPGEWYLKMLQCYRCRQWFHEACTQCLSDPMMFGDRFYVFFCSVCNQGPEYIKRLPLRWVDVVHLALYNLGVQSKKKYFDFEEILAFVNHHWDPLQLGKLTGTPVSERGPHLLNALNSYKSRFLCGKEIKKKKCIFRLRIRVPPNPPSKVLPEKAPGEGSTCELKRRGKSRYVHKDSLLPGQLQQQKRRAVRWKRAKFLLEDAIPSSDFTSAWSTNHHLASIFDFTLDEIQSLKSASSGQTFLSDVDSTDAVSTSGSATTSLSCESSRRTVGSRKRKQTVLTPPSARPKRGGGAAGRQPAVGSPQGSEVTCGPERPDDGIDSHTFESISEDDSSLSHLKSSISSYFGAAGRLVCGEKYQVLARRVTLEGKVQYLVEWEGTTPY", "length": 718, "header": "tr|A0A8V1AC69-1|A0A8V1AC69_CHICK Isoform 1 of PHD finger protein 19 OS=Gallus gallus OX=9031 GN=PHF19 PE=3 SV=1 CANONICAL=A0A8V1AC69-1" }, "locus": { "chromosome": "17", "start_pos": 8902576, "end_pos": 8896943, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066680.1", "url": "https://www.ensembl.org/id/ENSGALT00010066680.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040825.1", "url": "https://www.ensembl.org/id/ENSGALP00010040825.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:772213", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:772213", "resource": "KEGG Pathway" }, { "id": "R-GGA-212300", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-212300", "resource": "Reactome", "description": "PRC2 methylates histones and DNA" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AC69", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC69" } ], "pmid": "" }, { "name": "negative regulation of gene expression, epigenetic", "id": "GO:0045814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045814", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AC69", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC69" } ], "pmid": "" }, { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AC69", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC69" } ], "pmid": "" }, { "name": "stem cell differentiation", "id": "GO:0048863", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048863", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AC69", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC69" } ], "pmid": "" }, { "name": "stem cell population maintenance", "id": "GO:0019827", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019827", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AC69", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC69" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AC69", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC69" } ], "pmid": "" }, { "name": "histone H3K36me3 reader activity", "id": "GO:0140003", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140003", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AC69", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC69" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AC69", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC69" } ], "pmid": "" }, { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AC69", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC69" } ], "pmid": "" }, { "name": "histone H3K4me3 reader activity", "id": "GO:0140002", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140002", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AC69", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC69" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "ESC/E(Z) complex", "id": "GO:0035098", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035098", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AC69", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC69" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AC69", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC69" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 150, "end_pos": 152, "annotation": "n_glycosylation_sequon" }, { "start_pos": 21, "end_pos": 23, "annotation": "n_glycosylation_sequon" }, { "start_pos": 89, "end_pos": 91, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AC69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC69" }, { "id": "PS50016", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50016" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PHD-type", "eco_id": "ECO_0000259", "start_pos": 230, "end_pos": 285, "start_aa": "Glu", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 150, "end_pos": 152 }, { "start_pos": 21, "end_pos": 23 }, { "start_pos": 89, "end_pos": 91 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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"o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AC66-1", "uniprot_ac": "A0A8V1AC66", "uniprot_id": "A0A8V1AC66_CHICK", "mass": { "chemical_mass": 71368.0, "monoisotopic_mass": 71368.0 }, "refseq": { "ac": "XP_040551485", "name": "FAST kinase domain-containing protein 4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040551485" }, "gene_names": [ { "name": "TBRG4", "type": "recommended", "evidence": [ { "id": "A0A8V1AC66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC66" } ] }, { "name": "TBRG4", "type": "synonym", "evidence": [ { "id": "XP_040551485", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040551485" } ] } ], "protein_names": [ { "name": "FAST kinase domain-containing protein 4", "type": "recommended", "evidence": [ { "id": "A0A8V1AC66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC66/entry#names_and_taxonomy" } ] }, { "name": "FAST kinase domain-containing protein 4", "type": "synonym", "evidence": [ { "id": "XP_040551485", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040551485" } ] }, { "name": "Protein TBRG4", "type": "synonym", "evidence": [ { "id": "A0A8V1AC66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC66/entry#names_and_taxonomy" } ] }, { "name": "Transforming growth factor beta regulator 4", "type": "synonym", "evidence": [ { "id": "A0A8V1AC66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC66/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052533.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040551485", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040551485" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AC66", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC66" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TBRG4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC66", "locus": { "chromosome": "2", "start_pos": 4027628, "end_pos": 4018270, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010025951", "url": "https://www.ensembl.org/id/ENSGALG00010025951" } ] } } ], "crossref": [ { "id": "A0A8V1AC66", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AC66", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd23739", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd23739", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "420408", "url": "https://www.ncbi.nlm.nih.gov/gene/420408", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR010622", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010622", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013579", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013579", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013584", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013584", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050870", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050870", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:420408", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420408", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LCILQQA", "url": "https://omabrowser.org/oma/group/LCILQQA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A9W0", "url": "https://www.orthodb.org/?gene=A0A8V1A9W0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AC66", "url": "https://www.orthodb.org/?gene=A0A8V1AC66", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21228", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21228", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21228:SF59", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21228:SF59", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06743", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06743", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08368", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08368", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08373", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08373", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040551485", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040551485", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1A9W0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9W0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A9W0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9W0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AC66", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC66", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AC66-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC66-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAARLVQRCCWRHLATFTCSPAAATAALLLPSGKASAARALPHPPPASIHTSVPSTWNADRFSVKEQVEENSNSEHRVILNLIEAATSPQELFQLGELHSLNSNQASLVVTRLSRLAVEKKLETGDILQDERFQQLIEIVDSQISQVWNNTLVGLLKSLYSLGMESSSREMQSVEHEVLWRLRRLSFRQLASLAEFLAVKQGKESKLLSEVIKKLELRWTELEGTRTVVMLIAKVGHISSVLMDRLEDKALELAEQFSPEDIRRITLALAYQNRRSVPLLRAMSYHLIQKHSELNLSILMDLIFAYGKLNFHQPQVFQKIATDLQPHVSAMTPIEVTRCIRSFALLKWLSLPLFEAISQYALDNAKQLSISHLCNIILSFARLNFQPSGSEDFFNMAHEELQGQLDSLEPQLLTDLVWSLCVLQQAKPPYLQRVLAPDFHAVIQGDSSPKAQNLRMKLIQINAAAKLESPEYQGPFLPAGMLNAAEPAAEKVTLLQSSLQEALAGVLGSQDNGRWDVHTIYGWQIDAEMVLNSENKPLPLKDFAAPHLPHSEGTKPLPPGARRVAFLRWEFPNFSNRSKELLGRYAMARRHIQAAGFLVVDVPHYEFLELKLERQRAAYLRDKLHKVVAKELAS", "length": 634, "header": "tr|A0A8V1AC66-1|A0A8V1AC66_CHICK Isoform 1 of FAST kinase domain-containing protein 4 OS=Gallus gallus OX=9031 GN=TBRG4 PE=1 SV=1 CANONICAL=A0A8V1AC66-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A9W0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC66/entry#A0A8V1A9W0-1", "sequence": { "sequence": "MAARLVQRCCWRHLATFTCSPAAATAALLLPSGKASAARALPHPPPASIHTSVPSTWNADRFSVKEQVEENSNSEHRVILNLIEAATSPQELFQLGELHSLNSNQASLVVTRLSRLAVEKKLETGDILQDERFQQLIEIVDSQISQVWNNTLVGLLKSLYSLGMESSSREMQSVEHEVLWRLRRLSFRQLASLAEFLAVKQGKESKLLSEVIKKLELRWTELEGTRTVVMLIAKVGHISSVLMDRLEDKALELAEQFSPEDIRRITLALAYQNRRSVPLLRAMSYHLIQKHSELNLSILMDLIFAYGDSSPKAQNLRMKLIQINAAAKLESPEYQGPFLPAGMLNAAEPAAEKVTLLQSSLQEALAGVLGSQDNGRWDVHTIYGWQIDAEMVLNSENKPLPLKDFAAPHLPHSEGTKPLPPGARRVAFLRWEFPNFSNRSKELLGRYAMARRHIQAAGFLVVDVPHYEFLELKLERQRAAYLRDKLHKVVAKELAS", "length": 496, "header": "tr|A0A8V1A9W0-1|A0A8V1AC66_CHICK Computationally mapped isoform of FAST kinase domain-containing protein 4 OS=Gallus gallus OX=9031 GN=TBRG4 PE=1 SV=1 CANONICAL=A0A8V1AC66-1" }, "locus": { "chromosome": "2", "start_pos": 4027589, "end_pos": 4018912, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063272.1", "url": "https://www.ensembl.org/id/ENSGALT00010063272.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039058.1", "url": "https://www.ensembl.org/id/ENSGALP00010039058.1" } ] } }, { "isoform_ac": "A0A8V1AC66-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC66/entry#A0A8V1AC66-1", "sequence": { "sequence": "MAARLVQRCCWRHLATFTCSPAAATAALLLPSGKASAARALPHPPPASIHTSVPSTWNADRFSVKEQVEENSNSEHRVILNLIEAATSPQELFQLGELHSLNSNQASLVVTRLSRLAVEKKLETGDILQDERFQQLIEIVDSQISQVWNNTLVGLLKSLYSLGMESSSREMQSVEHEVLWRLRRLSFRQLASLAEFLAVKQGKESKLLSEVIKKLELRWTELEGTRTVVMLIAKVGHISSVLMDRLEDKALELAEQFSPEDIRRITLALAYQNRRSVPLLRAMSYHLIQKHSELNLSILMDLIFAYGKLNFHQPQVFQKIATDLQPHVSAMTPIEVTRCIRSFALLKWLSLPLFEAISQYALDNAKQLSISHLCNIILSFARLNFQPSGSEDFFNMAHEELQGQLDSLEPQLLTDLVWSLCVLQQAKPPYLQRVLAPDFHAVIQGDSSPKAQNLRMKLIQINAAAKLESPEYQGPFLPAGMLNAAEPAAEKVTLLQSSLQEALAGVLGSQDNGRWDVHTIYGWQIDAEMVLNSENKPLPLKDFAAPHLPHSEGTKPLPPGARRVAFLRWEFPNFSNRSKELLGRYAMARRHIQAAGFLVVDVPHYEFLELKLERQRAAYLRDKLHKVVAKELAS", "length": 634, "header": "tr|A0A8V1AC66-1|A0A8V1AC66_CHICK Isoform 1 of FAST kinase domain-containing protein 4 OS=Gallus gallus OX=9031 GN=TBRG4 PE=1 SV=1 CANONICAL=A0A8V1AC66-1" }, "locus": { "chromosome": "2", "start_pos": 4027589, "end_pos": 4018912, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063268.1", "url": "https://www.ensembl.org/id/ENSGALT00010063268.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039056.1", "url": "https://www.ensembl.org/id/ENSGALP00010039056.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:420408", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420408", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0AAA9S1P7-1", "protein_name": "FAST kinase domain-containing protein 4", "gene_name": "TBRG4", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAARLVRRCTCLLREAARLAPAVSPVGQLRLPQGTQKPLTSSATSPSSRLPGLLSEFVEKEQVFTPYTGRQEVEQLIEKATQPEELLELLGSGHCLQQNHAALALIQLSRLLSEKPKDKAALIQDARFWQLLHLVNSQITVVWHGTLVKLLRSLYTLGLPATSKDLRSVEQEVRWRMRRLKYKHLAFLAESSATYMQEQGSRELLAELLVHLERRWAEIEDRRMVVAMMMKTGHLSESLMNRLEDKHVLDRAQSITLPHLCNMLLAFARVNFRPEREDPFFSLVHEKLGSELVGLEPALQVDVVWALCVLQQVREAELQAVLRPEFHTQFLGGKSPKDQSTFQKLLHINATAQLEHPEYTGPLLPTSALVPSPSALEQKMTPLQKELQETLKGLLGSADKGSFMVPTQYGWVLDAEVLLDTESQLLPLRDFVAPHLTPPSGSQPLPPGAKRLAFLRWEFPNFNSRSKDLLGRFMLARRHLLAAGFLLVDVPYYEWMELKSEWQKSAYLKDKMRKAVAEELAK", "length": 522 }, "evidence": [ { "id": "A0A8V1AC66", "url": "https://omabrowser.org/oma/group/A0A8V1AC66/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "E7F3K7-1", "protein_name": "FAST kinase domain-containing protein 4", "gene_name": "tbrg4", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTTRLLCRWARWFPRSPRTATASARLQTSTVHHTEPLCLMTLSWIRPSVRHLCQGNELAKIDEGTVPYERTKLIKLVEKASTPDEVLQLWDQHGGTGSEAARCLIQLNLRVVEKGSKGVLLDPRCKSMQDTLNTQLSTVWNGSLVGLLRTLTMLGLPAHAPLLGAIQNEVLWRIRRLSYRHLSYLADWVAFQRKMGYENEVLTSTLLKQLELRWTELSDSRTITILMGRASLFTPSLMDKLEDKALELAESFTAEDMRRVALALASQNRRAVPLLRALSYHLNQKPSFELKTPLLLDIAYVYGKLNFSQTQFFKRLASELLPRLSELSSSEVSRCAKSLALLKWLHLPLFEGFAQHYVSNSEKYSTLQMCNLLMAFAKLNFQLGKEQFYLKVHKALEDSFTSLEPFLKTDLVWSLCVLNQANSDYISSVIKPDFQKKLSAGGIEGRTENYRQKLLNICAYAQLEPLGLAVDASAVLLPDRQSKAESSTSALQKTLHTALWSLANERKQALHTAVKTLYGWTIDGELVVDSENKPIDMENFKAPHLPEGGGADALPEGTRRIAFVAWDFSNFCLKSKDLLGRFAMQKRHLQLAGFIVVEVPYFEFLELKSDWQKVAYLKDKLGKAVAEEMAK", "length": 631 }, "evidence": [ { "id": "A0A8V1AC66", "url": "https://omabrowser.org/oma/group/A0A8V1AC66/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1ST47-1", "protein_name": "FAST kinase domain-containing protein 4", "gene_name": "TBRG4", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MASRLVRRCTCLLREAARLAPAMSPVGQPRLTRGAPRTLTSSATSPSSHLPGSLSELVERGQVFTPYPERQEVDHLIERATQPEEILALLGGGHCLHQNRAALMVIQLSRLLSEKPKDKALLIKDARFQHLLRLVNSQINAVWHGTLVKLLRSLYALGLPATSKELQSVEQEVRWRMRRLRYKHLAFLAESSATYMQEQGSQELLAELLVHLERRWTEIDDGRTVVAMMVKIGHLSQSLMNRLEDKHVLDRAQSIALPHLCNMLLAFARVNFRPEREDQFFSLVHEKLGSQLAGLEPALQVDVVWSLCVLQQAREAELQAVLRPELHGQFLGDKSPKDQSTFQKLLHINATAQLEHPEYTGPHLPSSALVPRPSALDKKVTPLQKELQETLKGLLGSANKGSFLVATRYGWILDAEVLLDADSQLLPLRDFVAPHLAQPSGSQPLPAGAKRLAFLCWEFPNFNSRSKDLLGRFVLARRHLLAAGFLLVDVPYYEWLELKSEWQKSAYLKDKMRKAVAEELAK", "length": 522 }, "evidence": [ { "id": "A0A8V1AC66", "url": "https://omabrowser.org/oma/group/A0A8V1AC66/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3HMC7-1", "protein_name": "FAST kinase domain-containing protein 4", "gene_name": "Tbrg4", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAVRLMKRCTCLLRDTTRLVPTITPVGRVRLAGVACKTLTSSVSSPSSGSLTELLGKEQVFTPYPEHQEVDHLIEKATRPEELLELLGGGYSLHRNHPALILIRLSYLLSEKPKEKALLVEDARFLQLVSRIDSQVSSIWHGTLVKLLRSMYTLVLPQMSKELRSVEQEVRWRLRRLKYKHLVFLVESCTSYMQEQHSQELLAELLMHLERRWTEINDSRTVVTMMMKAGHLSESLMNRLEDKCLELVEQFGPDELRKVLVTLAAQSRRSVPLLRAISYHLVQKPFPLTKGVLLDLAYAYGKLNFHQTQVSQRLAADLLPFVPSMTLGEVARCTKSFAFLKWLNLSLFEAFTQHLLSRVQDVSLTHLCSILLAFARLNFHPEQEDEFFKLVHEKLDSMLGSLEPTLQVDLVWALCVLQQVREAELQTVLHPGLHTQFLGSKSPKDQSTFQKLVHINTTALLEHPEYKGPFLPASAVALCPSSSSKQMTPLQKELQETLKELLGSTDQGRLDVVTQYGWVLDAEVLLDTDGHFLPLRDFVAPHLAQPVGNRPLPPGAKRIAFLRWEFPNFNSRSKDLLGRFVLARRHVLAAGFLVVDVPYYEWLDLKSGWQKGAYLKDKMRKAVAEELAK", "length": 629 }, "evidence": [ { "id": "A0A8V1AC66", "url": "https://omabrowser.org/oma/group/A0A8V1AC66/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q5M9G9-1", "protein_name": "FAST kinase domain-containing protein 4", "gene_name": "Tbrg4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAVRLMKQCTCLLREATRLVPTVAPVGRLRLAGVACKTLTSSVSSPSSGSLTELLGKEQVFTPYPEHQEVDYLIEKATRPEELLELLGGDHSLHHNHAALILIRLSYLLSEKPKEKALLVEDARFQQLVRLVDSQITSVWHGTLVKLLRSLYTLVLPQGSKELRSVEQEVRWRLRRLKYKHLVFLAESCAPFMKEQHSKELLAELLRHLERRWTEISDSRTLVSMMTMAGHLSESLMNRLEDKCLELVEQFGPDELRKVLMTLAAQSRRSVPLLRAISYHLVQKPFPMTKGMLLDLAYAYGKLSFHQTQVAQRLAADLLPFIPSMTPGEVARCAKSFAFLKWLNLPLFEAFTQHLLNSAQDVSLSHLCSVLLAFARLNFHPEQEDQFFNLVHEKLDSVLGSLEPALQVDLVWALCVLQQVQVAELQTVLHPGLHTRFLESKSPKDQSTFQKLVHINSTALLEYPEYKGPFLPASAVAPSPSPSNKKMTPLQKELQDALKALLGNNDTGSLEVATQYGWVLDAEVLLDAEGHFLPLRDFVAPHLAQPVGNQPLPPGAKRIAFLRWEFPNFNSRSKDLLGRFVLARRHVLAAGFLVVDVPYYEWLDLKSEWQKTAYLKDKMRKAVAEELAK", "length": 629 }, "evidence": [ { "id": "A0A8V1AC66", "url": "https://omabrowser.org/oma/group/A0A8V1AC66/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q91YM4-1", "protein_name": "FAST kinase domain-containing protein 4", "gene_name": "Tbrg4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAVRLMKRCTCLLREATRLVPTVAPVGRLRLAGVSCKTLTSSVSSPSSGSLAELLGKEQVFTPYPEHQELDFLIEKASRPEQLLELLGSDHSLHHNHAALILIRLSYLLSEKPKEKALLAEDARFQRLVKLVDSQITCVWHGTLVKLLRSLYTLVLPQISKELQSVEQEVRWRLRRLKYKHLVFLAESCASFMKEQHSQELLAELLMHLERRWTEINDSRTLVTMMTMAGHLSESLMNHLEDKCLELVEQFGPDELRKVLVTLAAQSRRSVPLLRAISYHLVQKPFPMTKGMLLDLAYAYGKLSFHQTQVSQRLAADLLPFIPSMTPGEVARCAKSFAFLKWLNLPLFEAFTQHLLSRVQDVSLSHVCSVLLAFARLNFHPEQEEDQFFSMVHEKLDPVLGSLEPALQVDLVWALCVLQHVHETELHTVLHPGLHARFLESKSPKDQSTFQKLVHINTTALLEHPEYKGPFLPASAVAPIPSPSNKKMTPLQKELQETLKALLGNTDKGSLEVATQYGWVLDAEVLLDADGHFLPLRNFVAPHLAQPVGNQPLPPGAKRIAFLRWEFPNFNSRSKDLLGRFVLARRHVLAAGFLVVDVPYYEWLDLKSEWQKSAYLKDKMRKAMAEELAK", "length": 630 }, "evidence": [ { "id": "A0A8V1AC66", "url": "https://omabrowser.org/oma/group/A0A8V1AC66/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q969Z0-1", "protein_name": "FAST kinase domain-containing protein 4", "gene_name": "TBRG4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAHLVKRCTCLLREAARQAPAMAPVGRLRLAWVAHKTLTSSATSPISHLPGSLMEPVEKERASTPYIEKQVDHLIKKATRPEELLELLGGSHDLDSNQAAMVLIRLSHLLSEKPEDKGLLIQDAHFHQLLCLLNSQIASVWHGTLSKLLGSLYALGIPKASKELQSVEQEVRWRMRKLKYKHLAFLAESCATLSQEQHSQELLAELLTHLERRWTEIEDSHTLVTVMMKVGHLSEPLMNRLEDKCLELVEHFGPNELRKVLVMLAAQSRRSVPLLRAISYHLVQKPFSLTKDVLLDVAYAYGKLSFHQTQVSQRLATDLLSLMPSLTSGEVAHCAKSFALLKWLSLPLFEAFAQHVLNRAQDITLPHLCSVLLAFARLNFHPDQEDQFFSLVHEKLGSELPGLEPALQVDLVWALCVLQQAREAELQAVLHPEFHIQFLGGKSQKDQNTFQKLLHINATALLEYPEYSGPLLPASAVAPGPSALDRKVTPLQKELQETLKGLLGSADKGSLEVATQYGWVLDAEVLLDSDGEFLPVRDFVAPHLAQPTGSQSPPPGSKRLAFLRWEFPNFNSRSKDLLGRFVLARRHIVAAGFLIVDVPFYEWLELKSEWQKGAYLKDKMRKAVAEELAK", "length": 631 }, "evidence": [ { "id": "A0A8V1AC66", "url": "https://omabrowser.org/oma/group/A0A8V1AC66/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "mitochondrial RNA processing", "id": "GO:0000963", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000963", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AC66", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC66" } ], "pmid": "" }, { "name": "regulation of mitochondrial mRNA stability", "id": "GO:0044528", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044528", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AC66", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC66" } ], "pmid": "" }, { "name": "mitochondrial mRNA processing", "id": "GO:0090615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090615", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AC66", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC66" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AC66", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC66" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AC66", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC66" } ], "pmid": "" }, { "name": "ribonucleoprotein granule", "id": "GO:0035770", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035770", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AC66", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC66" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 149, "end_pos": 151, "annotation": "n_glycosylation_sequon" }, { "start_pos": 295, "end_pos": 297, "annotation": "n_glycosylation_sequon" }, { "start_pos": 573, "end_pos": 575, "annotation": "n_glycosylation_sequon" }, { "start_pos": 576, "end_pos": 578, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AC66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC66" }, { "id": "PS51286", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51286" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RAP", "eco_id": "ECO_0000259", "start_pos": 564, "end_pos": 622, "start_aa": "Val", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 149, "end_pos": 151 }, { "start_pos": 295, "end_pos": 297 }, { "start_pos": 573, "end_pos": 575 }, { "start_pos": 576, "end_pos": 578 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AD39-1", "uniprot_ac": "A0A8V1AD39", "uniprot_id": "A0A8V1AD39_CHICK", "mass": { "chemical_mass": 108393.0, "monoisotopic_mass": 108393.0 }, "refseq": { "ac": "XP_004948787", "name": "scaffold attachment factor B1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004948787" }, "gene_names": [ { "name": "SAFB2", "type": "recommended", "evidence": [ { "id": "A0A8V1AD39", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD39" } ] }, { "name": "SAFB2", "type": "synonym", "evidence": [ { "id": "XP_004948787", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004948787" } ] } ], "protein_names": [ { "name": "Scaffold attachment factor B2", "type": "synonym", "evidence": [ { "id": "A0A8V1AD39", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD39/entry#names_and_taxonomy" } ] }, { "name": "scaffold attachment factor B1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_004948787", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004948787" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052559.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004948787.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004948787", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004948787" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AD39", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD39" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SAFB2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD39", "locus": {} } ], "crossref": [ { "id": "A0A8V1AD39", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AD39", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd12679", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12679", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "427046", "url": "https://www.ncbi.nlm.nih.gov/gene/427046", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003034", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003034", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034781", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034781", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036361", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036361", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051738", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051738", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:427046", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427046", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WNGGGDH", "url": "https://omabrowser.org/oma/group/WNGGGDH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AAA3", "url": "https://www.orthodb.org/?gene=A0A8V1AAA3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AD34", "url": "https://www.orthodb.org/?gene=A0A8V1AD34", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AD39", "url": "https://www.orthodb.org/?gene=A0A8V1AD39", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AF60", "url": "https://www.orthodb.org/?gene=A0A8V1AF60", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15683", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15683", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15683:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15683:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00076", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00076", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02037", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02037", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-3899300", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3899300", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_004948787", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004948787", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AAA3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAA3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AAA3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAA3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AD34", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD34", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AD34-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD34-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AD39", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD39", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AD39-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD39-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AF60", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF60", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AF60-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF60-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAESHSAAGQGEYVPLSGCGTPGSEPETRRLSELRVIDLRAELKRRSLDSGGNKSVLTERLRKAIEEEGGNPDEIPVVSENTIKRTPKRSSKGRRPDEEGAEDNGLEEDSGDGQEDIEASLDNLQDIDMMDISVLDEAEIDNGNAVDCGEDYSADHILDSLSDSKENADAEMKELPDQPTDYAVGNLEASPEFSEIKEESREIPVMMVEVEDVGNSFDAASSELIEIKEIEELPLEPENEKILDILGETCKSELLNEETSEAEQPHAQEASNVVPGKRLAEEEDALGAAQSEEDALDLDSKSAQAMARKEAKRLVVAKGETSEQTIEEEKLDSDSVGVESVSDQSSKRCQGLEASSGETAERGAGPEGKDSKEDGKKAEDKANSEESPATKESSASEGGDQKKSSVEEDRDSKQASKDEKGRAGSGSGRNLWVSGLSSSTRATDLKNLFSKYGKVVGAKVVTNARSPGARCYGFVTMSTSEEATKCINHLHRTELHGKMISVEKAKNEPAGKKPSDRKEGEARKEKDRHHSADSKSEKSVGVKKEEKADKKDDAKKSDKDSKDEKEGKEKEEQKAGASDRSRASKSASRGTERTVVMDKSKGEPVISVKTSASKERSTKSQDRKSESKEKQDILSFDKIKEQRERERQRQREREIRETERRRERERREREQRLQAMHERDERQRLQRERERLEFQRQRLDRERLERERLERERMHIEQERRREQERIQREREELRRQQEQLRYEQERRSAMRRPYDDGRRDDPYWPEAKRMALDDRYHSEFVRQDRFHDFDHRDRGRYQDHSLDRREGSRGIPDRDGQHYPDERHGGPERHARESRDGWGGYGSDRRMNEGRGIPPQTRDGRDWGDHGRKLEGHQDRSWQGNVAGGVMGRDHERWQGGDRGAPGQPGPGHAMHRGGMAGRGGFTQGPNQSHVAPSAAVQGGFAGQERTHRATEPRFARRY", "length": 960, "header": "tr|A0A8V1AD39-1|A0A8V1AD39_CHICK Isoform 1 of Scaffold attachment factor B2 OS=Gallus gallus OX=9031 GN=SAFB2 PE=1 SV=1 CANONICAL=A0A8V1AD39-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AAA3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD39/entry#A0A8V1AAA3-1", "sequence": { "sequence": "MAESHSAAGQGEYVPLSGCGTPGSEPETRRLSELRVIDLRAELKRRSLDSGGNKSVLTERLRKAIEEEGGNPDEIPVVSENTIKRTPKRSSKGRRPDEEGAEDNGLEEDSGDGQEDIEASLDNLQDIDMMDISVLDEAEIDNGNAVDCGEDYSADHILDSLSDSKENADAEMKELPDQPTDYAVGNLEASPEFSEIKEESREIPVMMVEVEDVGNSFDAASSELIEIKEIEELPLEPENEKILDILGETCKSELLNEETSEAEQPHAQEASNVVPGKRLAEEEDALGAAQSEEDALDLDSKSAQAMARKEAKRLVVAKGETSEQTIEEEKLDSDSVGVESVSDQSSKRCQGLEASSGETAERGAGPEGKDSKEDGKKAEDKANSEESPATKESSASEGGDQKKSSVEEDRDSKQASKDEKGRAGSGSGRNLWVSGLSSSTRATDLKNLFSKYGKVVGAKVVTNARSPGARCYGFVTMSTSEEATKCINHLHRTELHGKMISVEKAKNEPAGKKPSDRKEGEARKEKDRHHSADSKSEKSVGVKKEEKADKKDDAKKSDKDSKDEKEGKEKEEQKAGASDRSRASKSASRGTERTVVMDKSKGEPVISVKTSASKERSTKSQDRKSESKEKQDILSFDKIKEQRERERQRQREREIRETERRRERERREREQRLQAMHERDERQRLQRERERLEFQRQRLDRERLERERLERERMHIEQERRREQERIQREREELRRQQEQLRYEQERRSAMRRPYDDGRRDDPYWPEAKRMALDDRYHSEFVRQDRFHDFDHRDRGRYQDHSLDRREGSRGIPDRDGQHYPDERHGGPERHARESRDGWGGYGSDRRMNEGRGIPPQTRLVLGTPGSVVLVLRSRRGETFRG", "length": 882, "header": "tr|A0A8V1AAA3-1|A0A8V1AD39_CHICK Computationally mapped isoform of Scaffold attachment factor B2 OS=Gallus gallus OX=9031 GN=SAFB2 PE=1 SV=1 CANONICAL=A0A8V1AD39-1" }, "locus": { "chromosome": "28", "start_pos": 1785701, "end_pos": 1773716, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065888.1", "url": "https://www.ensembl.org/id/ENSGALT00010065888.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040154.1", "url": "https://www.ensembl.org/id/ENSGALP00010040154.1" } ] } }, { "isoform_ac": "A0A8V1AD34-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD39/entry#A0A8V1AD34-1", "sequence": { "sequence": "MAESHSAAGQGEYVPLSGCGTPGSEPETRRLSELRVIDLRAELKRRSLDSGGNKSVLTERLRKAIEEEGGNPDEIPVVSENTIKRTPKRSSKGRRPDEEGAEDNGLEEDSGDGQVEVEDVGNSFDAASSELIEIKEIEELPLEPENEKILDILGETCKSELLNEETSEAEQPHAQEASNVVPGKRLAEEEDALGAAQSEEDALDLDSKSAQAMARKEAKRLVVAKGETSEQTIEEEKLDSDSVGVESVSDQSSKRCQGLEASSGETAERGAGPEGKDSKEDGKKAEDKANSEESPATKESSASEGGDQKKSSVEEDRDSKQASKDEKGRAGSGSGRNLWVSGLSSSTRATDLKNLFSKYGKVVGAKVVTNARSPGARCYGFVTMSTSEEATKCINHLHRTELHGKMISVEKAKNEPAGKKPSDRKEGEARKEKDRHHSADSKSEKSVGVKKEEKADKKDDAKKSDKDSKDEKEGKEKEEQKAGASDRSRASKSASRGTERTVVMDKSKGEPVISVKTSASKERSTKSQDRKSESKEKQDILSFDKIKEQRERERQRQREREIRETERRRERERREREQRLQAMHERDERQRLQRERERLEFQRQRLDRERLERERLERERMHIEQERRREQERIQREREELRRQQEQLRYEQERRSAMRRPYDDGRRDDPYWPEAKRMALDDRYHSEFVRQDRFHDFDHRDRGRYQDHSLDRREGSRGIPDRDGQHYPDERHGGPERHARESRDGWGGYGSDRRMNEGRGIPPQTRDGRDWGDHGRKLEGHQDRSWQGNVAGGVMGRDHERWQGGDRGAPGQPGPGHAMHRGGMAGRGGFTQGPNQSHVAPSAAVQGGFAGQERTHRATEPRFARRY", "length": 867, "header": "tr|A0A8V1AD34-1|A0A8V1AD34_CHICK Computationally mapped isoform of Scaffold attachment factor B2 OS=Gallus gallus OX=9031 GN=SAFB2 PE=1 SV=1 CANONICAL=A0A8V1AD39-1" }, "locus": { "chromosome": "28", "start_pos": 1786884, "end_pos": 1773716, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065887.1", "url": "https://www.ensembl.org/id/ENSGALT00010065887.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040153.1", "url": "https://www.ensembl.org/id/ENSGALP00010040153.1" } ] } }, { "isoform_ac": "A0A8V1AD39-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD39/entry#A0A8V1AD39-1", "sequence": { "sequence": "MAESHSAAGQGEYVPLSGCGTPGSEPETRRLSELRVIDLRAELKRRSLDSGGNKSVLTERLRKAIEEEGGNPDEIPVVSENTIKRTPKRSSKGRRPDEEGAEDNGLEEDSGDGQEDIEASLDNLQDIDMMDISVLDEAEIDNGNAVDCGEDYSADHILDSLSDSKENADAEMKELPDQPTDYAVGNLEASPEFSEIKEESREIPVMMVEVEDVGNSFDAASSELIEIKEIEELPLEPENEKILDILGETCKSELLNEETSEAEQPHAQEASNVVPGKRLAEEEDALGAAQSEEDALDLDSKSAQAMARKEAKRLVVAKGETSEQTIEEEKLDSDSVGVESVSDQSSKRCQGLEASSGETAERGAGPEGKDSKEDGKKAEDKANSEESPATKESSASEGGDQKKSSVEEDRDSKQASKDEKGRAGSGSGRNLWVSGLSSSTRATDLKNLFSKYGKVVGAKVVTNARSPGARCYGFVTMSTSEEATKCINHLHRTELHGKMISVEKAKNEPAGKKPSDRKEGEARKEKDRHHSADSKSEKSVGVKKEEKADKKDDAKKSDKDSKDEKEGKEKEEQKAGASDRSRASKSASRGTERTVVMDKSKGEPVISVKTSASKERSTKSQDRKSESKEKQDILSFDKIKEQRERERQRQREREIRETERRRERERREREQRLQAMHERDERQRLQRERERLEFQRQRLDRERLERERLERERMHIEQERRREQERIQREREELRRQQEQLRYEQERRSAMRRPYDDGRRDDPYWPEAKRMALDDRYHSEFVRQDRFHDFDHRDRGRYQDHSLDRREGSRGIPDRDGQHYPDERHGGPERHARESRDGWGGYGSDRRMNEGRGIPPQTRDGRDWGDHGRKLEGHQDRSWQGNVAGGVMGRDHERWQGGDRGAPGQPGPGHAMHRGGMAGRGGFTQGPNQSHVAPSAAVQGGFAGQERTHRATEPRFARRY", "length": 960, "header": "tr|A0A8V1AD39-1|A0A8V1AD39_CHICK Isoform 1 of Scaffold attachment factor B2 OS=Gallus gallus OX=9031 GN=SAFB2 PE=1 SV=1 CANONICAL=A0A8V1AD39-1" }, "locus": { "chromosome": "28", "start_pos": 1786884, "end_pos": 1773716, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065892.1", "url": "https://www.ensembl.org/id/ENSGALT00010065892.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040158.1", "url": "https://www.ensembl.org/id/ENSGALP00010040158.1" } ] } }, { "isoform_ac": "A0A8V1AF60-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD39/entry#A0A8V1AF60-1", "sequence": { "sequence": "MAESHSAAGQGEYVPLSGCGTPGSEPETRRLSELRVIDLRAELKRRSLDSGGNKSVLTERLRKAIEEEGGNPDEIPVVSENTIKRTPKRSSKGRRPDEEGAEDNGLEEDSGDGQEDIEASLDNLQDIDMMDISVLDEAEIDNGNAVDCGEDYSADHILDSLSDSKENADAEMKELPDQPTDYAVGNLEASPEFSEIKEESREIPVMMVEVEDVGNSFDAASSELIEIKEIEELPLEPENEKILDILGETCKSELLNEETSEAEQPHAQEASNVVPGKRLAEEEDALGAAQSEEDALDLDSKSAQAMARKEAKRLVVAKGETSEQTIEEEKLDSDSVGVESVSDQSSKRCQGLEASSGETAERGAGPEGKDSKEDGKKAEDKANSEESPATKESSASEGGDQKKSSVEEDRDSKQASKDEKGRAGSGSGRNLWVSGLSSSTRATDLKNLFSKYGKVVGAKVVTNARSPGARCYGFVTMSTSEEATKCINHLHRTELHGKMISVEKAKNEPAGKKPSDRKEGEARKEKDRHHSADSKSEKSVGVKKEEKADKKDDAKKSDKDSKDEKEGKEKEEQKAGASDRSRASKSASRGTERTVVMDKSKGEPVISVKTSASKERSTKSQDRKSESKEKQDILSFDKIKEQRERERQRQREREIRETERRRERERREREQRLQAMHERDERQRLQRERERLEFQRQRLDRERLERERLERERMHIEQERRREQERIQREREELRRQQEQLRYEQERRSAMRRPYDDGRRDDPYWPEAKRMALDDRYHSEFVRQDRFHDFDHRDRGRYQDHSLDRREGSRGIPDRDGQHYPDERHGGPERHARESRDGWGGYGSDRRMNEGRGIPPQTRW", "length": 860, "header": "tr|A0A8V1AF60-1|A0A8V1AF60_CHICK Computationally mapped isoform of Scaffold attachment factor B2 OS=Gallus gallus OX=9031 GN=SAFB2 PE=1 SV=1 CANONICAL=A0A8V1AD39-1" }, "locus": { "chromosome": "28", "start_pos": 1786477, "end_pos": 1773716, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065890.1", "url": "https://www.ensembl.org/id/ENSGALT00010065890.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040156.1", "url": "https://www.ensembl.org/id/ENSGALP00010040156.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:427046", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427046", "resource": "KEGG Pathway" }, { "id": "R-GGA-3899300", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3899300", "resource": "Reactome", "description": "SUMOylation of transcription cofactors" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AD39", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD39" } ], "pmid": "" }, { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AD39", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD39" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AD39", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD39" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AD39", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD39" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 53, "end_pos": 55, "annotation": "n_glycosylation_sequon" }, { "start_pos": 928, "end_pos": 930, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AD39", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD39" }, { "id": "PS50102", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50102" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RRM", "eco_id": "ECO_0000259", "start_pos": 429, "end_pos": 507, "start_aa": "Arg", "end_aa": "Asn", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1AD39", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD39" }, { "id": "PS50800", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50800" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SAP", "eco_id": "ECO_0000259", "start_pos": 31, "end_pos": 65, "start_aa": "Leu", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 53, "end_pos": 55 }, { "start_pos": 928, "end_pos": 930 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1ACM2-1", "uniprot_ac": "A0A8V1ACM2", "uniprot_id": "A0A8V1ACM2_CHICK", "mass": { "chemical_mass": 56603.0, "monoisotopic_mass": 56603.0 }, "refseq": {}, "gene_names": [ { "name": "LOC769554", "type": "recommended", "evidence": [ { "id": "A0A8V1ACM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACM2" } ] } ], "protein_names": [ { "name": "Solute carrier family 2, facilitated glucose transporter member 5", "type": "recommended", "evidence": [ { "id": "A0A8V1ACM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACM2/entry#names_and_taxonomy" } ] }, { "name": "Fructose transporter", "type": "synonym", "evidence": [ { "id": "A0A8V1ACM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACM2/entry#names_and_taxonomy" } ] }, { "name": "Glucose transporter type 5, small intestine", "type": "synonym", "evidence": [ { "id": "A0A8V1ACM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACM2/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACM2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACM2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC769554", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACM2", "locus": {} } ], "crossref": [ { "id": "A0A8V1ACM2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1ACM2", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR005828", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005828", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005829", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005829", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020846", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020846", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036259", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036259", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045263", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045263", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AAC4", "url": "https://www.orthodb.org/?gene=A0A8V1AAC4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AAC9", "url": "https://www.orthodb.org/?gene=A0A8V1AAC9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ACM2", "url": "https://www.orthodb.org/?gene=A0A8V1ACM2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ACM7", "url": "https://www.orthodb.org/?gene=A0A8V1ACM7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23503", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23503", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23503:SF54", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23503:SF54", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00083", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00083", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "60372", "url": "https://www.rhea-db.org/rhea/60372", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1AAC4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAC4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AAC4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAC4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AAC9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAC9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AAC9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAC9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ACM2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACM2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ACM2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACM2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ACM7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACM7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ACM7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACM7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLGSGTLDVFHHLCQVQYRKLLLMILVLGIGGTHLGGFQLSVINYTSLYIQKFINETWLERYGSALHQETLTLFWSFIVSIYCIGGVIGCLCSGYLAAKYGKKKCLLINDVVLIIATLNTGFSRRAKSFEMILIGRFLEGICAGVCMNAHVQYAGEISPKKLRGFVNVTSSVFLALGKAVARVLGLRDLLGTEDMWNVLLSFSGFVALIQLLFLPFFPESPPYLFLQKGDKDGCLKAMKQLWGEENCRTEFDDMVKEKAVTKGTKIMNVLEMLKEPSVHPQLCTMLLLLLSLQLCGLSAITFYTLEIFQTANLHESIIPYVALGVAVSELISIIFCSSIIDRFGRRILLWGGYLLMALVLVLLETSLLLSDRFLWMRYCNVILIFLFIIAYGIGPAGAVSSVMNEIFTLSARSSAFVIGGIIIWLGLAFTGMIFPFAVMTLGPFCFLIFIAVLVVSSVLIYLFVPETKGKSTFEITEEFKTRRYKKKRHQTVENNVTEEKIYCTKL", "length": 506, "header": "tr|A0A8V1ACM2-1|A0A8V1ACM2_CHICK Isoform 1 of Solute carrier family 2, facilitated glucose transporter member 5 OS=Gallus gallus OX=9031 GN=LOC769554 PE=3 SV=1 CANONICAL=A0A8V1ACM2-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AAC4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACM2/entry#A0A8V1AAC4-1", "sequence": { "sequence": "MAGSLSELVQYRKLLLMILVLGIGGTHLGGFQLSVINYTSLYIQKFINETWLERYGSALHQETLTLFWSFIVSIYCIGGVIGCLCSGYLAAKYGKKKCLLINDVVLIIATLNTGFSRRAKSFEMILIGRFLEGICAAGAVSSVMNEIFTLSARSSAFVIGGIIIWLGLAFTGMIFPFAVMTLGPFCFLIFIAVLVVSSVLIYLFVPETKGKSTFEITEEFKTRRYKKKRHQTVENNVTEEKIYCTKL", "length": 247, "header": "tr|A0A8V1AAC4-1|A0A8V1ACM2_CHICK Computationally mapped isoform of Solute carrier family 2, facilitated glucose transporter member 5 OS=Gallus gallus OX=9031 GN=LOC769554 PE=3 SV=1 CANONICAL=A0A8V1ACM2-1" }, "locus": { "chromosome": "15", "start_pos": 8058246, "end_pos": 8050181, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063536.1", "url": "https://www.ensembl.org/id/ENSGALT00010063536.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039218.1", "url": "https://www.ensembl.org/id/ENSGALP00010039218.1" } ] } }, { "isoform_ac": "A0A8V1AAC9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACM2/entry#A0A8V1AAC9-1", "sequence": { "sequence": "MAGSLSELVQYRKLLLMILVLGIGGTHLGGFQLSVINYTSLYIQKFINETWLERYGSALHQETLTLFWSFIVSIYCIGGVIGCLCSGYLAAKYGKKKCLLINDVVLIIATLNTGFSRRAKSFEMILIGRFLEGICAGVCMNAHVQYAGEISPKKLRGFVNVTSSVFLALGKAVARVLGLRDLLGTEDMWNVLLSFSGFVALIQLLFLPFFPESPPYLFLQKGDKDGCLKAMKQLWGEENCRTEFDDMVKEKAVTKGTKIMNVLEMLKEPSVHPQLCTMLLLLLSLQLCGLSAITFYTLEIFQTANLHESIIPYVALGVAVSELISIIFCDRFLWMRYCNVILIFLFIIAYGIGPAGAVSSVMNEIFTLSARSSAFVIGGIIIWLGLAFTGMIFPFAVMTLGPFCFLIFIAVLVVSSVLIYLFVPETKGKSTFEITEEFKTRRYKKKRHQTVENNVTEEKIYCTKL", "length": 465, "header": "tr|A0A8V1AAC9-1|A0A8V1ACM2_CHICK Computationally mapped isoform of Solute carrier family 2, facilitated glucose transporter member 5 OS=Gallus gallus OX=9031 GN=LOC769554 PE=3 SV=1 CANONICAL=A0A8V1ACM2-1" }, "locus": { "chromosome": "15", "start_pos": 8058246, "end_pos": 8050181, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063542.1", "url": "https://www.ensembl.org/id/ENSGALT00010063542.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039223.1", "url": "https://www.ensembl.org/id/ENSGALP00010039223.1" } ] } }, { "isoform_ac": "A0A8V1ACM2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACM2/entry#A0A8V1ACM2-1", "sequence": { "sequence": "MLGSGTLDVFHHLCQVQYRKLLLMILVLGIGGTHLGGFQLSVINYTSLYIQKFINETWLERYGSALHQETLTLFWSFIVSIYCIGGVIGCLCSGYLAAKYGKKKCLLINDVVLIIATLNTGFSRRAKSFEMILIGRFLEGICAGVCMNAHVQYAGEISPKKLRGFVNVTSSVFLALGKAVARVLGLRDLLGTEDMWNVLLSFSGFVALIQLLFLPFFPESPPYLFLQKGDKDGCLKAMKQLWGEENCRTEFDDMVKEKAVTKGTKIMNVLEMLKEPSVHPQLCTMLLLLLSLQLCGLSAITFYTLEIFQTANLHESIIPYVALGVAVSELISIIFCSSIIDRFGRRILLWGGYLLMALVLVLLETSLLLSDRFLWMRYCNVILIFLFIIAYGIGPAGAVSSVMNEIFTLSARSSAFVIGGIIIWLGLAFTGMIFPFAVMTLGPFCFLIFIAVLVVSSVLIYLFVPETKGKSTFEITEEFKTRRYKKKRHQTVENNVTEEKIYCTKL", "length": 506, "header": "tr|A0A8V1ACM2-1|A0A8V1ACM2_CHICK Isoform 1 of Solute carrier family 2, facilitated glucose transporter member 5 OS=Gallus gallus OX=9031 GN=LOC769554 PE=3 SV=1 CANONICAL=A0A8V1ACM2-1" }, "locus": { "chromosome": "15", "start_pos": 8058246, "end_pos": 8051073, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063532.1", "url": "https://www.ensembl.org/id/ENSGALT00010063532.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039216.1", "url": "https://www.ensembl.org/id/ENSGALP00010039216.1" } ] } }, { "isoform_ac": "A0A8V1ACM7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACM2/entry#A0A8V1ACM7-1", "sequence": { "sequence": "MAGSLSELVQYRKLLLMILVLGIGGTHLGGFQLSVINYTSLYIQKFINETWLERYGSALHQETLTLFWSFIVSIYCIGGVIGCLCSGYLAAKYGKKKCLLINDVVLIIATLNTGFSRRAKSFEMILIGRFLEGICAGVCMNAHVQYAGEISPKKLRGFVNVTSSVFLALGKAVARVLGLRDLLGTEDMWNVLLSFSGFVALIQLLFLPFFPESPPYLFLQKGDKDGCLKAMKQLWGEENCRTEFDDMVKEKAVTKGTKIMNVLEMLKEPSVHPQLCTMLLLLLSLQLCGLSAITFYTLEIFQTANLHESIIPYVALGVAVSELISIIFCSSIIDRFGRRILLWGGYLLMALVLVLLETSLLLSDRFLWMRYCNVILIFLFIIAYGIGPAGAVSSVMNEIFTLSARSSAFVIGGIIIWLGLAFTGMIFPFAVVCNLLQISSSTLNLNCFSRLVWTGSKMKFL", "length": 461, "header": "tr|A0A8V1ACM7-1|A0A8V1ACM7_CHICK Computationally mapped isoform of Solute carrier family 2, facilitated glucose transporter member 5 OS=Gallus gallus OX=9031 GN=LOC769554 PE=3 SV=1 CANONICAL=A0A8V1ACM2-1" }, "locus": { "chromosome": "15", "start_pos": 8057818, "end_pos": 8050181, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063539.1", "url": "https://www.ensembl.org/id/ENSGALT00010063539.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039221.1", "url": "https://www.ensembl.org/id/ENSGALP00010039221.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACM2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACM2" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACM2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACM2" } ], "pmid": "" }, { "name": "sarcolemma", "id": "GO:0042383", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042383", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACM2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACM2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "transmembrane transporter activity", "id": "GO:0022857", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022857", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACM2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACM2" } ], "pmid": "" }, { "name": "fructose transmembrane transporter activity", "id": "GO:0005353", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005353", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACM2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACM2" } ], "pmid": "" }, { "name": "D-glucose transmembrane transporter activity", "id": "GO:0055056", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055056", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACM2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACM2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "dehydroascorbic acid transport", "id": "GO:0070837", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070837", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACM2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACM2" } ], "pmid": "" }, { "name": "fructose import across plasma membrane", "id": "GO:1990539", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990539", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACM2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACM2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 167, "end_pos": 169, "annotation": "n_glycosylation_sequon" }, { "start_pos": 44, 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"field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1ADF9-1", "uniprot_ac": "A0A8V1ADF9", "uniprot_id": "A0A8V1ADF9_CHICK", "mass": { "chemical_mass": 45429.0, "monoisotopic_mass": 45429.0 }, "refseq": {}, "gene_names": [ { "name": "ARRDC2", "type": "recommended", "evidence": [ { "id": "A0A8V1ADF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF9" } ] } ], "protein_names": [ { "name": "Arrestin domain containing 2", "type": "synonym", "evidence": [ { "id": "A0A8V1ADF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF9/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADF9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ARRDC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF9", "locus": { "chromosome": "28", "start_pos": 4494301, "end_pos": 4500592, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027232", "url": "https://www.ensembl.org/id/ENSGALG00010027232" } ] } } ], "crossref": [ { "id": "A0A8V1ADF9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1ADF9", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR011021", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011021", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011022", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011022", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014752", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014752", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014756", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014756", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050357", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050357", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AAN3", "url": "https://www.orthodb.org/?gene=A0A8V1AAN3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ADF9", "url": "https://www.orthodb.org/?gene=A0A8V1ADF9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11188", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11188", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11188:SF48", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11188:SF48", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00339", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00339", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02752", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02752", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1AAN3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAN3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AAN3-1", "url": 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"Ensembl Peptide", "id": "ENSGALP00010040292.1", "url": "https://www.ensembl.org/id/ENSGALP00010040292.1" } ] } }, { "isoform_ac": "A0A8V1ADF9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF9/entry#A0A8V1ADF9-1", "sequence": { "sequence": "MLFDRLKRFLIVLEGAERGSPAAFSPGQAVVGRVVLELAAAARCGALRLRALGAARVHWTESRSAGSSTAYTQSYSDQVEFLSHRDTLLAPPDNGEVTVLQAGRHEFPFTFQLPETLATSFEGKHGSVRYWVKAKLHRPWATVKKVKKEFTVIEPIDINTPALLAPQAGAKEKLARAWYCNRGQVSVSAKIDRKGYTPGLGSVSNMCVCSAGEVIPIFAEIDNCTNRAVVPKAAIIQTQTFIARGTKKQKKSVVTSIVGDSIAAGKREAWHGRALKIPPVGPSILQCRIIQVEYSLKVCVDIPGTSKLLLELPLVIGTIPLHPFGSRTSSVSSQYSVTLDWLSSIPEQPEAPPEYSAVVPSPTAEQSLAPPCRGELGAVLEGPFFAYIQEFRFRPPPLYSEIDPNPPSDGIRPRCMTC", "length": 418, "header": "tr|A0A8V1ADF9-1|A0A8V1ADF9_CHICK Isoform 1 of Arrestin domain containing 2 OS=Gallus gallus OX=9031 GN=ARRDC2 PE=3 SV=1 CANONICAL=A0A8V1ADF9-1" }, "locus": { "chromosome": "28", "start_pos": 4497544, "end_pos": 4495121, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066025.1", "url": "https://www.ensembl.org/id/ENSGALT00010066025.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040291.1", "url": "https://www.ensembl.org/id/ENSGALP00010040291.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 363, "start_aa": "Thr", "end_pos": 363, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr363", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "molecular adaptor activity", "id": "GO:0060090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060090", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADF9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADF9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF9" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADF9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF9" } ], "pmid": "" }, { "name": "cytoplasmic vesicle", "id": "GO:0031410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031410", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADF9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 223, "end_pos": 225, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1ADF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF9" }, { "id": "SM01017", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM01017" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Arrestin C-terminal-like", "eco_id": "ECO_0000259", "start_pos": 181, "end_pos": 321, "start_aa": "Asn", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 363 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 223, "end_pos": 225 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AAT5-1", "uniprot_ac": "A0A8V1AAT5", "uniprot_id": "A0A8V1AAT5_CHICK", "mass": { "chemical_mass": 51660.0, "monoisotopic_mass": 51660.0 }, "refseq": {}, "gene_names": [ { "name": "NR6A1", "type": "recommended", "evidence": [ { "id": "A0A8V1AAT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAT5" } ] } ], "protein_names": [ { "name": "Nuclear receptor subfamily 6 group A member 1", "type": "synonym", "evidence": [ { "id": "A0A8V1AAT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAT5/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAT5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAT5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NR6A1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAT5", "locus": { "chromosome": "17", "start_pos": 10059970, "end_pos": 10121692, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028917", "url": "https://www.ensembl.org/id/ENSGALG00010028917" } ] } } ], "crossref": [ { "id": "A0A8V1AAT5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AAT5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000001073", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000001073", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd06953", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06953", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd07169", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07169", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "772325", "url": "https://www.ncbi.nlm.nih.gov/gene/772325", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000536", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000536", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001628", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001628", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001723", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001723", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013088", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013088", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035500", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035500", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050200", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050200", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AAT0", "url": "https://www.orthodb.org/?gene=A0A8V1AAT0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AAT5", "url": "https://www.orthodb.org/?gene=A0A8V1AAT5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AG53", "url": "https://www.orthodb.org/?gene=A0A8V1AG53", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AI77", "url": "https://www.orthodb.org/?gene=A0A8V1AI77", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AKD8", "url": "https://www.orthodb.org/?gene=A0A8V1AKD8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AM53", "url": "https://www.orthodb.org/?gene=A0A8V1AM53", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AM57", "url": "https://www.orthodb.org/?gene=A0A8V1AM57", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NVM8", "url": "https://www.orthodb.org/?gene=F1NVM8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48092", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48092", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00104", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00104", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00105", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00105", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-383280", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-383280", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1AAT0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAT0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AAT0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAT0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AAT5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAT5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AAT5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAT5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AG53", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG53", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AG53-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG53-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AI77", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI77", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AI77-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI77-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AKD8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKD8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AKD8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKD8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AM53", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM53", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AM53-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM53-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AM57", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM57", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AM57-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM57-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NVM8", "url": "https://www.uniprot.org/uniprotkb/F1NVM8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NVM8-1", "url": "https://www.uniprot.org/uniprotkb/F1NVM8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRRFATDVEQMSSSAVLPMNSMANDRVDQRTCLICGDRATGLHYGIISCEGCKGFFKRSICNKRVYRCSRDKNCVMSRKQRNRCQYCRLLKCLQMGMNRKAIREDGMPGGRNKSIGPVQISEEEIERIMSGQEFEGEANMSWSNNGDSDHSSPGNGVSESNQPSPVSTPSSSRSVELNGFAALRDQYIGTPVSTHYQYLPHLFSYSAHSALVPPQARSLDPQSHSLINQLVSAEDLEPLGTPMLIEDGYKVTQAELFALLCRLADELLFRQIAWIKKLPFFCELSIKDYTCLLSSTWQELILLSSLTVYSKQIFGDLADVTSKYSPSDDELHRFSEEGMEVMERLIYLFRKFNQLKVSNEEYACMKAINFLNQDIRGLTNASQLEQLNKRYWYVCQDFTEYKYPHQPNRFPDLMMCLPEIRYIAGKMVNVPLEQLPLLFKAVLHSCKTSVSKE", "length": 453, "header": "tr|A0A8V1AAT5-1|A0A8V1AAT5_CHICK Isoform 1 of Nuclear receptor subfamily 6 group A member 1 OS=Gallus gallus OX=9031 GN=NR6A1 PE=3 SV=1 CANONICAL=A0A8V1AAT5-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AAT0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAT5/entry#A0A8V1AAT0-1", "sequence": { "sequence": "MPRRDDRVDQRTCLICGDRATGLHYGIISCEGCKGFFKRSICNKRVYRCSRDKNCVMSRKQRNRCQYCRLLKCLQMGMNRKAIREDGMPGGRNKSIGPVQISEEEIERIMSGQEFEGEANMSWSNNGDSDHSSPGNGVSESNQPSPVSTPSSRSVELNGFAALRDQYIGTPVSTHYQYLPHLFSYSAHSALVPPQARSLDPQSHSLINQLVSAEDLEPLGTPMLIEDGYKVTQAELFALLCRLADELLFRQIAWIKKLPFFCELSIKDYTCLLSSTWQELILLSSLTVYSKQIFGDLADVTSKYSPSDDELHRFSEEGMEVMERLIYLFRKFNQLKVSNEEYACMKAINFLNQDIRGLTNASQLEQLNKRYWYVCQDFTEYKYPHQPNRFPDLMMCLPEIRYIAGKMVNVPLEQLPLLFKAVLHSCKTSVSKE", "length": 433, "header": "tr|A0A8V1AAT0-1|A0A8V1AAT5_CHICK Computationally mapped isoform of Nuclear receptor subfamily 6 group A member 1 OS=Gallus gallus OX=9031 GN=NR6A1 PE=3 SV=1 CANONICAL=A0A8V1AAT5-1" }, "locus": { "chromosome": "17", "start_pos": 10083062, "end_pos": 10062464, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069958.1", "url": "https://www.ensembl.org/id/ENSGALT00010069958.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043084.1", "url": "https://www.ensembl.org/id/ENSGALP00010043084.1" } ] } }, { "isoform_ac": "A0A8V1AAT5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAT5/entry#A0A8V1AAT5-1", "sequence": { "sequence": "MRRFATDVEQMSSSAVLPMNSMANDRVDQRTCLICGDRATGLHYGIISCEGCKGFFKRSICNKRVYRCSRDKNCVMSRKQRNRCQYCRLLKCLQMGMNRKAIREDGMPGGRNKSIGPVQISEEEIERIMSGQEFEGEANMSWSNNGDSDHSSPGNGVSESNQPSPVSTPSSSRSVELNGFAALRDQYIGTPVSTHYQYLPHLFSYSAHSALVPPQARSLDPQSHSLINQLVSAEDLEPLGTPMLIEDGYKVTQAELFALLCRLADELLFRQIAWIKKLPFFCELSIKDYTCLLSSTWQELILLSSLTVYSKQIFGDLADVTSKYSPSDDELHRFSEEGMEVMERLIYLFRKFNQLKVSNEEYACMKAINFLNQDIRGLTNASQLEQLNKRYWYVCQDFTEYKYPHQPNRFPDLMMCLPEIRYIAGKMVNVPLEQLPLLFKAVLHSCKTSVSKE", "length": 453, "header": "tr|A0A8V1AAT5-1|A0A8V1AAT5_CHICK Isoform 1 of Nuclear receptor subfamily 6 group A member 1 OS=Gallus gallus OX=9031 GN=NR6A1 PE=3 SV=1 CANONICAL=A0A8V1AAT5-1" }, "locus": { "chromosome": "17", "start_pos": 10119141, "end_pos": 10062464, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069963.1", "url": "https://www.ensembl.org/id/ENSGALT00010069963.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043089.1", "url": "https://www.ensembl.org/id/ENSGALP00010043089.1" } ] } }, { "isoform_ac": "A0A8V1AG53-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAT5/entry#A0A8V1AG53-1", "sequence": { "sequence": "MELEPPAELPEPRAAAAKGAPRNDDRVDQRTCLICGDRATGLHYGIISCEGCKGFFKRSICNKRVYRCSRDKNCVMSRKQRNRCQYCRLLKCLQMGMNRKAIREDGMPGGRNKSIGPVQISEEEIERIMSGQEFEGEANMSWSNNGDSDHSSPGNGVSESNQPSPVSTPSSSRSVELNGFAALRDQYIGTPVSTHYQYLPHLFSYSAHSALVPPQARSLDPQSHSLINQLVSAEDLEPLGTPMLIEDGYKVTQAELFALLCRLADELLFRQIAWIKKLPFFCELSIKDYTCLLSSTWQELILLSSLTVYSKQIFGDLADVTSKYSPSDDELHRFSEEGMEVMERLIYLFRKFNQLKVSNEEYACMKAINFLNQDIRGLTNASQLEQLNKRYWYVCQDFTEYKYPHQPNRFPDLMMCLPEIRYIAGKMVNVPLEQLPLLFKAVLHSCKTSVSKE", "length": 453, "header": "tr|A0A8V1AG53-1|A0A8V1AAT5_CHICK Computationally mapped isoform of Nuclear receptor subfamily 6 group A member 1 OS=Gallus gallus OX=9031 GN=NR6A1 PE=3 SV=1 CANONICAL=A0A8V1AAT5-1" }, "locus": { "chromosome": "17", "start_pos": 10121601, "end_pos": 10062464, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069965.1", "url": "https://www.ensembl.org/id/ENSGALT00010069965.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043091.1", "url": "https://www.ensembl.org/id/ENSGALP00010043091.1" } ] } }, { "isoform_ac": "A0A8V1AI77-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAT5/entry#A0A8V1AI77-1", "sequence": { "sequence": "MFPATDVEQMSSSAVLPMNSMANDRVDQRTCLICGDRATGLHYGIISCEGCKGFFKRSICNKRVYRCSRDKNCVMSRKQRNRCQYCRLLKCLQMGMNRKAIREDGMPGGRNKSIGPVQISEEEIERIMSGQEFEGEANMSWSNNGDSDHSSPGNGVSESNQPSPVSTPSSSRSVELNGFAALRDQYIGTPVSTHYQYLPHLFSYSAHSALVPPQARSLDPQSHSLINQLVSAEDLEPLGTPMLIEDGYKVTQAELFALLCRLADELLFRQIAWIKKLPFFCELSIKDYTCLLSSTWQELILLSSLTVYSKQIFGDLADVTSKYSPSDDELHRFSEEGMEVMERLIYLFRKFNQLKVSNEEYACMKAINFLNQDIRGLTNASQLEQLNKRYWYVCQDFTEYKYPHQPNRFPDLMMCLPEIRYIAGKMVNVPLEQLPLLFKAVLHSCKTSVSKE", "length": 452, "header": "tr|A0A8V1AI77-1|A0A8V1AAT5_CHICK Computationally mapped isoform of Nuclear receptor subfamily 6 group A member 1 OS=Gallus gallus OX=9031 GN=NR6A1 PE=3 SV=1 CANONICAL=A0A8V1AAT5-1" }, "locus": { "chromosome": "17", "start_pos": 10113906, "end_pos": 10062464, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069962.1", "url": "https://www.ensembl.org/id/ENSGALT00010069962.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043088.1", "url": "https://www.ensembl.org/id/ENSGALP00010043088.1" } ] } }, { "isoform_ac": "A0A8V1AKD8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAT5/entry#A0A8V1AKD8-1", "sequence": { "sequence": "MFPGTCRMGDDRVDQRTCLICGDRATGLHYGIISCEGCKGFFKRSICNKRVYRCSRDKNCVMSRKQRNRCQYCRLLKCLQMGMNRKAIREDGMPGGRNKSIGPVQISEEEIERIMSGQEFEGEANMSWSNNGDSDHSSPGNGVSESNQPSPVSTPSSSRSVELNGFAALRDQYIGTPVSTHYQYLPHLFSYSAHSALVPPQARSLDPQSHSLINQLVSAEDLEPLGTPMLIEDGYKVTQAELFALLCRLADELLFRQIAWIKKLPFFCELSIKDYTCLLSSTWQELILLSSLTVYSKQIFGDLADVTSKYSPSDDELHRFSEEGMEVMERLIYLFRKFNQLKVSNEEYACMKAINFLNQDIRGLTNASQLEQLNKRYWYVCQDFTEYKYPHQPNRFPDLMMCLPEIRYIAGKMVNVPLEQLPLLFKAVLHSCKTSVSKE", "length": 439, "header": "tr|A0A8V1AKD8-1|A0A8V1AAT5_CHICK Computationally mapped isoform of Nuclear receptor subfamily 6 group A member 1 OS=Gallus gallus OX=9031 GN=NR6A1 PE=3 SV=1 CANONICAL=A0A8V1AAT5-1" }, "locus": { "chromosome": "17", "start_pos": 10113906, "end_pos": 10062464, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069961.1", "url": "https://www.ensembl.org/id/ENSGALT00010069961.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043087.1", "url": "https://www.ensembl.org/id/ENSGALP00010043087.1" } ] } }, { "isoform_ac": "A0A8V1AM53-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAT5/entry#A0A8V1AM53-1", "sequence": { "sequence": "MAACSAGPREERCFAAVRDLIRDDRVDQRTCLICGDRATGLHYGIISCEGCKGFFKRSICNKRVYRCSRDKNCVMSRKQRNRCQYCRLLKCLQMGMNRKAIREDGMPGGRNKSIGPVQISEEEIERIMSGQEFEGEANMSWSNNGDSDHSSPGNGVSESNQPSPVSTPSSSRSVELNGFAALRDQYIGTPVSTHYQYLPHLFSYSAHSALVPPQARSLDPQSHSLINQLVSAEDLEPLGTPMLIEDGYKVTQAELFALLCRLADELLFRQIAWIKKLPFFCELSIKDYTCLLSSTWQELILLSSLTVYSKQIFGDLADVTSKYSPSDDELHRFSEEGMEVMERLIYLFRKFNQLKVSNEEYACMKAINFLNQDIRGLTNASQLEQLNKRYWYVCQDFTEYKYPHQPNRFPDLMMCLPEIRYIAGKMVNVPLEQLPLLFKAVLHSCKTSVSKE", "length": 452, "header": "tr|A0A8V1AM53-1|A0A8V1AAT5_CHICK Computationally mapped isoform of Nuclear receptor subfamily 6 group A member 1 OS=Gallus gallus OX=9031 GN=NR6A1 PE=3 SV=1 CANONICAL=A0A8V1AAT5-1" }, "locus": { "chromosome": "17", "start_pos": 10082896, "end_pos": 10062464, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", 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"tr|F1NVM8-1|A0A8V1AAT5_CHICK Computationally mapped isoform of Nuclear receptor subfamily 6 group A member 1 OS=Gallus gallus OX=9031 GN=NR6A1 PE=3 SV=4 CANONICAL=A0A8V1AAT5-1" }, "locus": { "chromosome": "17", "start_pos": 10095078, "end_pos": 10062464, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069960.1", "url": "https://www.ensembl.org/id/ENSGALT00010069960.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043086.1", "url": "https://www.ensembl.org/id/ENSGALP00010043086.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 168, "start_aa": "Thr", "end_pos": 168, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr168", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-GGA-383280", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-383280", "resource": "Reactome", "description": "Nuclear Receptor transcription pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 9, "go_terms": [ { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAT5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAT5" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAT5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAT5" } ], "pmid": "" }, { "name": "sequence-specific DNA binding", "id": "GO:0043565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043565", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAT5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAT5" } ], "pmid": "" }, { "name": "estrogen response element binding", "id": "GO:0034056", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034056", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAT5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAT5" } ], "pmid": "" }, { "name": "nuclear receptor activity", "id": "GO:0004879", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004879", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAT5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAT5" } ], "pmid": "" }, { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAT5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAT5" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAT5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAT5" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAT5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAT5" } ], "pmid": "" }, { "name": "DNA-binding transcription repressor activity", "id": "GO:0001217", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001217", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAT5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAT5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAT5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAT5" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAT5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAT5" } ], "pmid": "" }, { "name": "transcription regulator complex", "id": "GO:0005667", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005667", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAT5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAT5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAT5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAT5" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAT5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAT5" } ], "pmid": "" }, { "name": "positive regulation of mesenchymal stem cell differentiation", "id": "GO:2000741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000741", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAT5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAT5" } ], "pmid": "" }, { "name": "gamete generation", "id": "GO:0007276", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007276", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAT5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAT5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 112, "end_pos": 114, "annotation": "n_glycosylation_sequon" }, { 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"uniprotkb_annotation": "Nuclear receptor", "eco_id": "ECO_0000259", "start_pos": 29, "end_pos": 104, "start_aa": "Gln", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 168 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 112, "end_pos": 114 }, { "start_pos": 139, "end_pos": 141 }, { "start_pos": 380, "end_pos": 382 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { 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] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AAT7-1", "uniprot_ac": "A0A8V1AAT7", "uniprot_id": "A0A8V1AAT7_CHICK", "mass": { "chemical_mass": 69216.0, "monoisotopic_mass": 69216.0 }, "refseq": { "ac": "XP_015155491", "name": "SHC-transforming protein 2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015155491" }, "gene_names": [ { "name": "SHC2", "type": "recommended", "evidence": [ { "id": "A0A8V1AAT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAT7" } ] }, { "name": "SHC2", "type": "synonym", "evidence": [ { "id": "XP_015155491", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015155491" } ] } ], "protein_names": [ { "name": "SHC adaptor protein 2", "type": "synonym", "evidence": [ { "id": "A0A8V1AAT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAT7/entry#names_and_taxonomy" } ] }, { "name": "SHC-transforming protein 2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015155491", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015155491" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052559.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015155491.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015155491", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015155491" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAT7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAT7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SHC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAT7", "locus": {} } ], "crossref": [ { "id": "A0A8V1AAT7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AAT7", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd01209", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01209", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd09925", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09925", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "770341", "url": "https://www.ncbi.nlm.nih.gov/gene/770341", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000980", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000980", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006019", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006019", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006020", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006020", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035676", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035676", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036860", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036860", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051235", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051235", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "GDEWSRK", "url": "https://omabrowser.org/oma/group/GDEWSRK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AAT7", "url": "https://www.orthodb.org/?gene=A0A8V1AAT7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10337", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10337", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10337:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10337:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00017", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00017", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00640", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00640", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-167044", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-167044", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-4420097", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4420097", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5673001", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5673001", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015155491", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015155491", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AAT7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAT7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AAT7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAT7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLPEPKYDRFRDEPLRAAARPRHPPAVPMPAPAPAHPGAAPGLAQPCPAAGEEPEAGTTFCMLLPRMPQWKFPGPGGFLSRSPSGSSKELSSPAKAGGAVEPGGATSSLAAVLGACEPGCSAPCSLQVMSRLRGGAGAARKAARVEGARPAGDEWNRKGSFINKPAQGWLHPDERVLGPGVSYIVRYMGCIEVLRSMRSLDFNTRTQVTREAINRLYEAVPGVKGIWKKKAPSKALFSILGKSNLRFAGMSIAVNISIDGLNLMIPTTRQIIANHHMQSISFASGGDMQQDMSPKHPLCPQDTTDYVAYVAKDPINQRACHILECCDGLAQSVINTVGQAFELRFKQYLHSPPKAVVPPDRVLGMEESAWGEDDEAAEHDYYNSIPGKEPPPGGLIDSRLQHSAFPGRIRVQPSHQGGLALRRELSSQPGQPWDPENQGQSCDGYLQADGHPLVPRDYEEHMYVNTQSLESDATHTAPEESPKKDLFDMRPFEDALKLHRCIAGSNVSPPIEDQWPSPPTRKAPIAPTEEQLRREPWYHGKMSRRDAEKLLQMDGDFLVRDSITNPGQYVLTGMHSGQPKHLLLVDPEGVVRTKDVLFESISHLISHHRQNEQPIVAAESELHLRQVVQRKQ", "length": 632, "header": "tr|A0A8V1AAT7-1|A0A8V1AAT7_CHICK Isoform 1 of SHC adaptor protein 2 OS=Gallus gallus OX=9031 GN=SHC2 PE=4 SV=1 CANONICAL=A0A8V1AAT7-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AAT7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAT7/entry#A0A8V1AAT7-1", "sequence": { "sequence": "MLPEPKYDRFRDEPLRAAARPRHPPAVPMPAPAPAHPGAAPGLAQPCPAAGEEPEAGTTFCMLLPRMPQWKFPGPGGFLSRSPSGSSKELSSPAKAGGAVEPGGATSSLAAVLGACEPGCSAPCSLQVMSRLRGGAGAARKAARVEGARPAGDEWNRKGSFINKPAQGWLHPDERVLGPGVSYIVRYMGCIEVLRSMRSLDFNTRTQVTREAINRLYEAVPGVKGIWKKKAPSKALFSILGKSNLRFAGMSIAVNISIDGLNLMIPTTRQIIANHHMQSISFASGGDMQQDMSPKHPLCPQDTTDYVAYVAKDPINQRACHILECCDGLAQSVINTVGQAFELRFKQYLHSPPKAVVPPDRVLGMEESAWGEDDEAAEHDYYNSIPGKEPPPGGLIDSRLQHSAFPGRIRVQPSHQGGLALRRELSSQPGQPWDPENQGQSCDGYLQADGHPLVPRDYEEHMYVNTQSLESDATHTAPEESPKKDLFDMRPFEDALKLHRCIAGSNVSPPIEDQWPSPPTRKAPIAPTEEQLRREPWYHGKMSRRDAEKLLQMDGDFLVRDSITNPGQYVLTGMHSGQPKHLLLVDPEGVVRTKDVLFESISHLISHHRQNEQPIVAAESELHLRQVVQRKQ", "length": 632, "header": "tr|A0A8V1AAT7-1|A0A8V1AAT7_CHICK Isoform 1 of SHC adaptor protein 2 OS=Gallus gallus OX=9031 GN=SHC2 PE=4 SV=1 CANONICAL=A0A8V1AAT7-1" }, "locus": { "chromosome": "28", "start_pos": 3076016, "end_pos": 3072169, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066086.1", "url": "https://www.ensembl.org/id/ENSGALT00010066086.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040352.1", "url": "https://www.ensembl.org/id/ENSGALP00010040352.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-167044", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-167044", "resource": "Reactome", "description": "Signalling to RAS" }, { "id": "R-GGA-4420097", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4420097", "resource": "Reactome", "description": "VEGFA-VEGFR2 Pathway" }, { "id": "R-GGA-5673001", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5673001", "resource": "Reactome", "description": "RAF/MAP kinase cascade" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8M6YXA6-1", "protein_name": "SHC-transforming protein 2 isoform X1", "gene_name": "shc2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLLKPKYDRFRNDSVTSSDDLMQSLAMSGKVVATPVASSSAPGLELPPLQTAALPPPSAQVLADSPGMDSEQDGTTTFCMLIPKMPQWKFSNSLLSRSPSNSSSSSNSSKDSGRAPPTDSSPAAASGGTAAASGPVASLAAVFNSCDPVCVGPCSLQASRRQRASQRESSAGAAEGSPGGSGSFRTGMNRRTRVEGIWLGDNFTQKGSFINKPSQGWLHPDKKISSTGASYIVRYMGCIEVLKSMRSLDFSTRTQVTREAINRLCESVPGGKTAWKKKTTNKTLQSIMGKSNLRFAGMSIGVNISIDGLSLLVPTTRQVIAHHPMQSISFASGGDSDTPDYVAYVAKDPVNQRACHILECCDGLAQNVISTIGQAFELQFKQYLHSPPKAIPAMDRNIRTEESAWGEDEESSEHDYYNSIPGKEPPVGGVVDSRLRPPAGLLGHVHTHPQSKTSQMGSPAKRDANSLPATHLCYEVHWDTENNRSSTGLTSDGYLRADGHPPGSRDYEEHLYVNTQNLDNLEASVVGRRPESPKKDIFDMRPFEDALRLHEASGVCVLEDKWPSPPRRRAPVAPTEDQLRREMWYHGRMSRRDAENLLGRDGDFLVRDSATNPGQYVLTGMQCGLPKHLLLVDPEGVVRTKDMLFESISHLINYHLTNKLPIVAAESELHLQQVVCRKI", "length": 679 }, "evidence": [ { "id": "A0A8V1AAT7", "url": "https://omabrowser.org/oma/group/A0A8V1AAT7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "O70142-1", "protein_name": "SHC-transforming protein 2", "gene_name": "Shc2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTQGPGGRAAPEPEAPTTFCALLPRMPQWKFAAPGSFLGRGPAAARVAGAAEAQPEPGVPALAAVLGACEPRCAAPCPLPALGRCRGSGSRGARGTPDVADEWVRKGGFIHKPAHGWLHPDARVLGPGVSYIVRYMGCIEVLRSMRSLDFNTRTQVTREAINRLHEAVPGVRGSWKKKAPNKALASILGKSNLRFAGMSISVNISVDGLNLSVPATRQIIANHHMQSISFASGGDTDMTDYVAYVAKDPINQRACHILECCEGLAQSVISTVGQAFELRFKQYLHSPPKAVVPPERLTGLEESAWGDGEVTADHDYYNSIPGKEPPLGGLVDSRLAVTQPCALTTLGGLGQGLSPAWRDVRGLPWDMGPSGAVPPGDGYVQADARGPHDYEEHLYVNTQGLDALELEDTSETPLQPEDSPKKDLFDMRPFEDALKLHECSVAAGITAASLPLEDQWPSPPTRRAPIAPTEEQLRQEPWYHGRMSRRAAEKLLRADGDFLVRDSITNPGQYVLTGMHAGQPKHLLLVDPEGVVRTKDVLFESISHLIDYHLKNGLPIVAAESELHLRGVVSREP", "length": 573 }, "evidence": [ { "id": "A0A8V1AAT7", "url": "https://omabrowser.org/oma/group/A0A8V1AAT7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P98077-1", "protein_name": "SHC-transforming protein 2", "gene_name": "SHC2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTQGPGGRAPPAPPAPPEPEAPTTFCALLPRMPQWKFAAPGGFLGRGPAAARAAGASGGADPQPEPAGPGGVPALAAAVLGACEPRCAAPCPLPALSRCRGAGSRGSRGGRGAAGSGDAAAAAEWIRKGSFIHKPAHGWLHPDARVLGPGVSYVVRYMGCIEVLRSMRSLDFNTRTQVTREAINRLHEAVPGVRGSWKKKAPNKALASVLGKSNLRFAGMSISIHISTDGLSLSVPATRQVIANHHMPSISFASGGDTDMTDYVAYVAKDPINQRACHILECCEGLAQSIISTVGQAFELRFKQYLHSPPKVALPPERLAGPEESAWGDEEDSLEHNYYNSIPGKEPPLGGLVDSRLALTQPCALTALDQGPSPSLRDACSLPWDVGSTGTAPPGDGYVQADARGPPDHEEHLYVNTQGLDAPEPEDSPKKDLFDMRPFEDALKLHECSVAAGVTAAPLPLEDQWPSPPTRRAPVAPTEEQLRQEPWYHGRMSRRAAERMLRADGDFLVRDSVTNPGQYVLTGMHAGQPKHLLLVDPEGVVRTKDVLFESISHLIDHHLQNGQPIVAAESELHLRGVVSREP", "length": 582 }, "evidence": [ { "id": "A0A8V1AAT7", "url": "https://omabrowser.org/oma/group/A0A8V1AAT7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BMC3-1", "protein_name": "SHC-transforming protein 2", "gene_name": "Shc2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTQGPGGRAAPEPEAPTTFCALLPRMPQWKFAAPGSFLGRGPAATRVAGVAEAQPEPGVPALAAVLGACEPRCAAPCPLPALGRCRGSGTRGARVTPDVADEWVRKGGFIHKPAHGWLHPDARVLGPGVSYIVRYMGCIEVLRSMRSLDFNTRTQVTREAINRLHEAVPGVRGSWKKKAPNKALASILGKSNLRFAGMSISVNISVDGLNLSVPATRQIIANHHMQSISFASGGDTDMTDYVAYVAKDPINQRACHILECCEGLAQSVISTVGQAFELRFKQYLHSPPKAVVPPERLTGLEELAWGDDDAAADHNYYNSIPGKEPPLGGLVDSRLAVTQPCALATLGGLGQGMTPVWRDARGLPWDMGPSGAAPPGDGYVQADARGPHDYEEHLYVNTQGLDAVELEDTAEAPLQFEDSPKKDLFDMRPFEDALKLHACSVAAGITAASPPLEDQWPSPPTRRAPIAPTEEQLRQEPWYHGRMSRRAAEKLLRADGDFLVRDSVTNPGQYVLTGMHAGQPKHLLLVDPEGVVRTKDVLFESISHLIDYHLKNGLPIVAAESELHLRGVVSREP", "length": 573 }, "evidence": [ { "id": "A0A8V1AAT7", "url": "https://omabrowser.org/oma/group/A0A8V1AAT7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAT7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAT7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "cell surface receptor protein tyrosine kinase signaling pathway", "id": "GO:0007169", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007169", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAT7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAT7" } ], "pmid": "" }, { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAT7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAT7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "receptor tyrosine kinase binding", "id": "GO:0030971", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030971", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAT7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAT7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 255, "end_pos": 257, "annotation": "n_glycosylation_sequon" }, { "start_pos": 506, "end_pos": 508, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AAT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAT7" }, { "id": "PS01179", "database": "PROSITE", "url": "https://prosite.expasy.org/PS01179" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PID", "eco_id": "ECO_0000259", "start_pos": 177, "end_pos": 372, "start_aa": "Leu", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1AAT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAT7" }, { "id": "PS50001", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50001" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SH2", "eco_id": "ECO_0000259", "start_pos": 537, "end_pos": 628, "start_aa": "Trp", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 255, "end_pos": 257 }, { "start_pos": 506, "end_pos": 508 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": 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"o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AAT8-1", "uniprot_ac": "A0A8V1AAT8", "uniprot_id": "A0A8V1AAT8_CHICK", "mass": { "chemical_mass": 23682.0, "monoisotopic_mass": 23682.0 }, "refseq": {}, "gene_names": [ { "name": "OAZ1", "type": "recommended", "evidence": [ { "id": "A0A8V1AAT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAT8" } ] } ], "protein_names": [ { "name": "Ornithine decarboxylase antizyme 1", "type": "recommended", "evidence": [ { "id": "A0A8V1AAT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAT8/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAT8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAT8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "OAZ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAT8", "locus": { "chromosome": "28", "start_pos": 2418623, "end_pos": 2422576, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": 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"https://www.ensembl.org/id/ENSGALG00010027884" } ] } } ], "crossref": [ { "id": "A0A8V1AAU7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AAU7", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR031781", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031781", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052092", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052092", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AAU7", "url": "https://www.orthodb.org/?gene=A0A8V1AAU7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AG71", "url": "https://www.orthodb.org/?gene=A0A8V1AG71", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23205", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23205", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23205:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23205:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF16835", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16835", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-9770562", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9770562", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1AAU7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAU7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AAU7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAU7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AG71", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG71", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AG71-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG71-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMALLQSLFSFYCPLPSLTIAHKSPIGCIAQFIFPLNSPLFHFGLQYKTWLLYLPAVLCSAQCVSVCAPQQLRFSRHPQELWLKTFCLINGKQNPVIFCCLGLPRAEIILCCPLCGVLSLLIFFTVTKQRDPETGQQSLLFQIDYPEIAESIMPRHRFMSAYEQRIEPPDRRWQYLLMAAEPYETIAFKVPSREIDKAEGKFWTHWNRETKQFFLQFHFKMEKPPAPPNLPPGPPTVKRPPPPPLMNGLPPRPPLPDSMPPPPPGGMTLPPMPPSGPVPPPPVPPQLPPAPGVPPPAPLPPMMRPPLPTEGPGTIPPPPPSN", "length": 322, "header": "tr|A0A8V1AAU7-1|A0A8V1AAU7_CHICK Isoform 1 of Splicing factor 3a subunit 2 OS=Gallus gallus OX=9031 GN=SF3A2 PE=1 SV=1 CANONICAL=A0A8V1AAU7-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AAU7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAU7/entry#A0A8V1AAU7-1", "sequence": { "sequence": "MMALLQSLFSFYCPLPSLTIAHKSPIGCIAQFIFPLNSPLFHFGLQYKTWLLYLPAVLCSAQCVSVCAPQQLRFSRHPQELWLKTFCLINGKQNPVIFCCLGLPRAEIILCCPLCGVLSLLIFFTVTKQRDPETGQQSLLFQIDYPEIAESIMPRHRFMSAYEQRIEPPDRRWQYLLMAAEPYETIAFKVPSREIDKAEGKFWTHWNRETKQFFLQFHFKMEKPPAPPNLPPGPPTVKRPPPPPLMNGLPPRPPLPDSMPPPPPGGMTLPPMPPSGPVPPPPVPPQLPPAPGVPPPAPLPPMMRPPLPTEGPGTIPPPPPSN", "length": 322, "header": "tr|A0A8V1AAU7-1|A0A8V1AAU7_CHICK Isoform 1 of Splicing factor 3a subunit 2 OS=Gallus gallus OX=9031 GN=SF3A2 PE=1 SV=1 CANONICAL=A0A8V1AAU7-1" }, "locus": { "chromosome": "28", "start_pos": 2451518, "end_pos": 2449559, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067576.1", "url": "https://www.ensembl.org/id/ENSGALT00010067576.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041319.1", "url": "https://www.ensembl.org/id/ENSGALP00010041319.1" } ] } }, { "isoform_ac": "A0A8V1AG71-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAU7/entry#A0A8V1AG71-1", "sequence": { "sequence": "MDFQHRPGGKTGSGGVASASESNRDRRERLRQLALETIDINKDPYFMKNHLGSYECKLCLTYFRIMLAPSAGTEAVLVEIILCCPLCGVLSLLIFFTVTKQRDPETGQQSLLFQIDYPEIAESIMPRHRFMSAYEQRIEPPDRRWQYLLMAAEPYETIAFKVPSREIDKAEGKFWTHWNRETKQFFLQFHFKMEKPPAPPNLPPGPPTVKRPPPPPLMNGLPPRPPLPDSMPPPPPGGMTLPPMPPSGPVPPPPVPPQLPPAPGVPPPAPLPPMMRPPLPTEGPGTIPPPPPSN", "length": 294, "header": "tr|A0A8V1AG71-1|A0A8V1AAU7_CHICK Computationally mapped isoform of Splicing factor 3a subunit 2 OS=Gallus gallus OX=9031 GN=SF3A2 PE=1 SV=1 CANONICAL=A0A8V1AAU7-1" }, "locus": { "chromosome": "28", "start_pos": 2453510, "end_pos": 2449559, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067582.1", "url": "https://www.ensembl.org/id/ENSGALT00010067582.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041325.1", "url": "https://www.ensembl.org/id/ENSGALP00010041325.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 309, "start_aa": "Thr", "end_pos": 309, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr309", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-GGA-9770562", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9770562", "resource": "Reactome", "description": "mRNA Polyadenylation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAU7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAU7" } ], "pmid": "" }, { "name": "catalytic step 2 spliceosome", "id": "GO:0071013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071013", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAU7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAU7" } ], "pmid": "" }, { "name": "U2 snRNP", "id": "GO:0005686", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005686", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAU7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAU7" } ], "pmid": "" }, { "name": "U2-type prespliceosome", "id": "GO:0071004", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071004", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAU7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAU7" } ], "pmid": "" }, { "name": "U2-type precatalytic spliceosome", "id": "GO:0071005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071005", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAU7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAU7" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAU7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAU7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAU7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAU7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "spliceosomal complex assembly", "id": "GO:0000245", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000245", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAU7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAU7" } ], "pmid": "" }, { "name": "U2-type prespliceosome assembly", "id": "GO:1903241", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903241", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAU7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAU7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AAU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAU7" }, { "id": "PF16835", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SF3A2", "eco_id": "ECO_0000259", "start_pos": 124, "end_pos": 213, "start_aa": "Phe", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 309 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AAV0-1", "uniprot_ac": "A0A8V1AAV0", "uniprot_id": "A0A8V1AAV0_CHICK", "mass": { "chemical_mass": 76319.0, "monoisotopic_mass": 76319.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "A0A8V1AAV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAV0/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAV0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAV0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAV0", "locus": {} } ], "crossref": [ { "id": "A0A8V1AAV0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AAV0", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR000477", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000477", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001037", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001037", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001584", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001584", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002156", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002156", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003308", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003308", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010661", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010661", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012337", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012337", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017856", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017856", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036397", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036397", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036862", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036862", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043128", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043128", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043502", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043502", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR41694", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR41694", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR41694:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR41694:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00075", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00075", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00078", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00078", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00552", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00552", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00665", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00665", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02022", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02022", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF06817", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06817", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1AAV0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAV0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AAV0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAV0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MACSPTICQLVVNTIIAPVRRDMPDCQIVHYMDDLLLAAPTGSQLQALEARVSGTLTGAGFTISQEKVQRGPGIEFLGYKFRSSTVIPEGLEIKPHVTNLWDVQKLVGAIQWVRGALGIPPRLMKPFYDQLKGSDPRERREWTPEMDAAWREILSLSSTASLSRWTPGIPLEGAVTRCQDGAVAVIGHALGSCPQPLRWLFSAQPVRAFTPWVELLSLLLSKARTSAFRDFGKDLDIVHLPRFFRDSQILPDEILLALHGFGGKLRYAGSLPIFELARPLQVSLRLRVVASPLDGPTVFTDASSLTGQGAVVWKNQTGDWEIRTFQDHSVSVQTLEAQAVAIALLLWPDTPCNVVTDSAFIAKMLLRMGQEGQPNTSIAFLLEEALTARTAPAAVLHVRSHSDVPGFFTTGNALADQHAGHKVLTVREARDLHSTLHLGARALSRTCSIPMAVAREVVQACPHCNSAPALSAGVNPRGIAPLDVWQTDFTLEPRLAPRSWLAVTVDTASTVIVATQHGRANSSAAQHHWSVCVATLGLPSHIETDNGSCFISRSTKEWLARWGITHSTGIPGNSQGQAIVERANRLLKEKLCVLGEGENYRGKIPVSQQGELLARALYALNHFERGENHRTPMQKHWQPRIIEEGPPVKIKIDNGLWESGWSILVWGRGYAAVKNKESGNIIWVPSRKVKPEFGLK", "length": 696, "header": "tr|A0A8V1AAV0-1|A0A8V1AAV0_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=3 SV=1 CANONICAL=A0A8V1AAV0-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AAV0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAV0/entry#A0A8V1AAV0-1", "sequence": { "sequence": "MACSPTICQLVVNTIIAPVRRDMPDCQIVHYMDDLLLAAPTGSQLQALEARVSGTLTGAGFTISQEKVQRGPGIEFLGYKFRSSTVIPEGLEIKPHVTNLWDVQKLVGAIQWVRGALGIPPRLMKPFYDQLKGSDPRERREWTPEMDAAWREILSLSSTASLSRWTPGIPLEGAVTRCQDGAVAVIGHALGSCPQPLRWLFSAQPVRAFTPWVELLSLLLSKARTSAFRDFGKDLDIVHLPRFFRDSQILPDEILLALHGFGGKLRYAGSLPIFELARPLQVSLRLRVVASPLDGPTVFTDASSLTGQGAVVWKNQTGDWEIRTFQDHSVSVQTLEAQAVAIALLLWPDTPCNVVTDSAFIAKMLLRMGQEGQPNTSIAFLLEEALTARTAPAAVLHVRSHSDVPGFFTTGNALADQHAGHKVLTVREARDLHSTLHLGARALSRTCSIPMAVAREVVQACPHCNSAPALSAGVNPRGIAPLDVWQTDFTLEPRLAPRSWLAVTVDTASTVIVATQHGRANSSAAQHHWSVCVATLGLPSHIETDNGSCFISRSTKEWLARWGITHSTGIPGNSQGQAIVERANRLLKEKLCVLGEGENYRGKIPVSQQGELLARALYALNHFERGENHRTPMQKHWQPRIIEEGPPVKIKIDNGLWESGWSILVWGRGYAAVKNKESGNIIWVPSRKVKPEFGLK", "length": 696, "header": "tr|A0A8V1AAV0-1|A0A8V1AAV0_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=3 SV=1 CANONICAL=A0A8V1AAV0-1" }, "locus": { "chromosome": "17", "start_pos": 256333, "end_pos": 254246, "strand": "+", "evidence": [ { "database": "Ensembl 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"mass": { "chemical_mass": 44544.0, "monoisotopic_mass": 44544.0 }, "refseq": { "ac": "XP_040534342", "name": "Krueppel-like factor 2 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040534342" }, "gene_names": [ { "name": "LOC424577", "type": "recommended", "evidence": [ { "id": "A0A8V1AAV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAV8" } ] }, { "name": "LOC424577", "type": "synonym", "evidence": [ { "id": "XP_040534342", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040534342" } ] } ], "protein_names": [ { "name": "C2H2-type domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8V1AAV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAV8/entry#names_and_taxonomy" } ] }, { "name": "Krueppel-like factor 2 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_040534342", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040534342" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052580.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040534342", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040534342" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAV8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAV8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC424577", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAV8", "locus": {} } ], "crossref": [ { "id": "A0A8V1AAV8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AAV8", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd22056", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22056", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "424577", "url": "https://www.ncbi.nlm.nih.gov/gene/424577", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR23235", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23235", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23235:SF175", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23235:SF175", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040534342", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040534342", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AAV8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAV8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AAV8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAV8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAAVDESALPSISTFTNLLPLEERPPDMMHRMLPHDGSAAAVKREEDELGKFVDLDFILAHTSSGGQGPPGPNYPLPETPESCGTTYDSDGSYPTPGKFPAPYPDGQSHSYVAELLTPDLPAHCDLQRREYTELRVPGGPHHHPALHPALSRPLPLDPSQPFGPRIKKEQPEERACMLGLPGGEYLGPGGGEHKPPRMAPGPVSGPPLPYPGFAHGRLGPPEEPLPGADPHLLADLPPHYAVAPHRYAPHFAPQPPPQFHGHFSVFREPLKGPGPGPAGLPGLLVTPPNSPVLEYFPAGGPPEDCKPKRGRRSWARKRTATHNCEYPGCGKTYTKSSHLKAHMRTHTGEKPYHCTWEGCGWKFARSDELTRHYRKHTGHRPFQCHLCERAFSRSDHLALHMKRHM", "length": 406, "header": "tr|A0A8V1AAV8-1|A0A8V1AAV8_CHICK Isoform 1 of C2H2-type domain-containing protein OS=Gallus gallus OX=9031 GN=LOC424577 PE=3 SV=1 CANONICAL=A0A8V1AAV8-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AAV8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAV8/entry#A0A8V1AAV8-1", "sequence": { "sequence": "MAAAVDESALPSISTFTNLLPLEERPPDMMHRMLPHDGSAAAVKREEDELGKFVDLDFILAHTSSGGQGPPGPNYPLPETPESCGTTYDSDGSYPTPGKFPAPYPDGQSHSYVAELLTPDLPAHCDLQRREYTELRVPGGPHHHPALHPALSRPLPLDPSQPFGPRIKKEQPEERACMLGLPGGEYLGPGGGEHKPPRMAPGPVSGPPLPYPGFAHGRLGPPEEPLPGADPHLLADLPPHYAVAPHRYAPHFAPQPPPQFHGHFSVFREPLKGPGPGPAGLPGLLVTPPNSPVLEYFPAGGPPEDCKPKRGRRSWARKRTATHNCEYPGCGKTYTKSSHLKAHMRTHTGEKPYHCTWEGCGWKFARSDELTRHYRKHTGHRPFQCHLCERAFSRSDHLALHMKRHM", "length": 406, "header": "tr|A0A8V1AAV8-1|A0A8V1AAV8_CHICK Isoform 1 of C2H2-type domain-containing protein OS=Gallus gallus OX=9031 GN=LOC424577 PE=3 SV=1 CANONICAL=A0A8V1AAV8-1" }, "locus": { "chromosome": "8", "start_pos": 20106558, "end_pos": 20104457, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010062363.1", "url": "https://www.ensembl.org/id/ENSGALT00010062363.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038554.1", "url": "https://www.ensembl.org/id/ENSGALP00010038554.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 96, "start_aa": "Thr", "end_pos": 96, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr96", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { 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"MAAQVAAVRAVSRAPEEPPPLPSGERPGRPRGGGRRRRAAPGEAAGGKRARLSQPLLAGPGPAEPLPPAALPGLPAAAAGLFAFSPLSLPPPPAALEERRHHHHRHRPEPGRPTAGQPQKARRGSPADGAAGRPSKRETQDENGKTQRADSLIMKKIKKKKKKKHREDVRGKRLKMYNKEVQTVCAGLTRIDKETLSQGQCDNLEMNKESFRYLKDEQLCRLNLGMQEYRVPQGVQTPFVTHQEHSVRSSFLKTGTKFSNFIHEEHQSNGGALVLHAYMDELSFLSPVEMERFAEEFLALSFSENDKNAAYYALAIVHGAAAYLPDFLDYFAFNFPNTPVKMEILGKKDIETTTISNFHSQVNRTYCCGTYRAGPMRQISLVGAVDEEVGDYFPEFLDMLEESPFLRMTLPWGTLSSLRLQCRSQSDDGPIMWVRPGEQMIPTADMPKSPFKRRRSMNEIKNLQYLPRTSEPREVLFEDRTRAHADHVGQGFDWQSTAAVGVLKAVQFGEWSDQPRITKDVVCFHAEDFTDVVQRLQLDLHEPPVSQCVQWVDEAKLNQMRREGIRYARIQLCDNDIYFIPRNVIHQFKTVSAVCSLAWHIRLKQYHPVGETSQNTESDSNLNSSIPGKTESKGEPRCVSVKTECEEPGIEMQLTTGMLSSVSSLSGLVQADQVAQPLPGFKIESDQQHNPQDHAGSSV", "length": 699, "header": "tr|A0A8V1AAX6-1|A0A8V1AAX6_CHICK Isoform 1 of Round spermatid basic protein 1 like OS=Gallus gallus OX=9031 GN=RSBN1 PE=3 SV=1 CANONICAL=A0A8V1AAX6-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AAX6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAX6/entry#A0A8V1AAX6-1", "sequence": { "sequence": "MAAQVAAVRAVSRAPEEPPPLPSGERPGRPRGGGRRRRAAPGEAAGGKRARLSQPLLAGPGPAEPLPPAALPGLPAAAAGLFAFSPLSLPPPPAALEERRHHHHRHRPEPGRPTAGQPQKARRGSPADGAAGRPSKRETQDENGKTQRADSLIMKKIKKKKKKKHREDVRGKRLKMYNKEVQTVCAGLTRIDKETLSQGQCDNLEMNKESFRYLKDEQLCRLNLGMQEYRVPQGVQTPFVTHQEHSVRSSFLKTGTKFSNFIHEEHQSNGGALVLHAYMDELSFLSPVEMERFAEEFLALSFSENDKNAAYYALAIVHGAAAYLPDFLDYFAFNFPNTPVKMEILGKKDIETTTISNFHSQVNRTYCCGTYRAGPMRQISLVGAVDEEVGDYFPEFLDMLEESPFLRMTLPWGTLSSLRLQCRSQSDDGPIMWVRPGEQMIPTADMPKSPFKRRRSMNEIKNLQYLPRTSEPREVLFEDRTRAHADHVGQGFDWQSTAAVGVLKAVQFGEWSDQPRITKDVVCFHAEDFTDVVQRLQLDLHEPPVSQCVQWVDEAKLNQMRREGIRYARIQLCDNDIYFIPRNVIHQFKTVSAVCSLAWHIRLKQYHPVGETSQNTESDSNLNSSIPGKTESKGEPRCVSVKTECEEPGIEMQLTTGMLSSVSSLSGLVQADQVAQPLPGFKIESDQQHNPQDHAGSSV", "length": 699, "header": "tr|A0A8V1AAX6-1|A0A8V1AAX6_CHICK Isoform 1 of Round spermatid basic protein 1 like OS=Gallus gallus OX=9031 GN=RSBN1 PE=3 SV=1 CANONICAL=A0A8V1AAX6-1" }, "locus": { "chromosome": "26", "start_pos": 3787333, "end_pos": 3774196, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067607.1", "url": "https://www.ensembl.org/id/ENSGALT00010067607.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041350.1", "url": "https://www.ensembl.org/id/ENSGALP00010041350.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "histone H4K20 demethylase activity", "id": "GO:0035575", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035575", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAX6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAX6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAX6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAX6" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAX6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAX6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "spermatogenesis", "id": "GO:0007283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007283", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAX6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAX6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 363, "end_pos": 365, "annotation": "n_glycosylation_sequon" }, { "start_pos": 623, "end_pos": 625, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 363, "end_pos": 365 }, { "start_pos": 623, "end_pos": 625 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AAZ4-1", "uniprot_ac": "A0A8V1AAZ4", "uniprot_id": "A0A8V1AAZ4_CHICK", "mass": { "chemical_mass": 25732.0, "monoisotopic_mass": 25732.0 }, "refseq": { "ac": "XP_415762", "name": "uroplakin-3b-like protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_415762" }, "gene_names": [ { "name": "UPK3BL", "type": "recommended", "evidence": [ { "id": "A0A8V1AAZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAZ4" } ] }, { "name": "UPK3BL", "type": "synonym", "evidence": [ { "id": "XP_415762", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_415762" } ] } ], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "A0A8V1AAZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAZ4/entry#names_and_taxonomy" } ] }, { "name": "uroplakin-3b-like protein 1", "type": "synonym", "evidence": [ { "id": "XP_415762", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_415762" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052550.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_415762.3. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_415762", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_415762" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAZ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAZ4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "UPK3BL", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAZ4", "locus": {} } ], "crossref": [ { "id": "A0A8V1AAZ4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AAZ4", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd09969", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09969", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "417514", "url": "https://www.ncbi.nlm.nih.gov/gene/417514", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR024831", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024831", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:417514", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417514", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "IYTCYDT", "url": "https://omabrowser.org/oma/group/IYTCYDT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AAZ4", "url": "https://www.orthodb.org/?gene=A0A8V1AAZ4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15446", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15446", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15446:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15446:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "XP_415762", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_415762", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AAZ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAZ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AAZ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAZ4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRPLLLLLLATAHGLDKLSYKPTLVGGNVEGRMTGSTFVLEQPRCVFDSYSTANIWLVVATREGMDAFNDSAQPGMPEWSFQRFPTNTSAYLTLGAMQYHYGCPKPDRELTVLRVGSETDCADNISVPNCNGPLPGPGPYWVKFLALNGSEPTATTEWSGPITLKTAREPQSIPGTGGARSGAMIAITAILSVLLAILLAALLATLCSSEACGVGSFRPDAASIRRYNTHHVYDQPAARL", "length": 240, "header": "tr|A0A8V1AAZ4-1|A0A8V1AAZ4_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN=UPK3BL PE=4 SV=1 CANONICAL=A0A8V1AAZ4-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AAZ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAZ4/entry#A0A8V1AAZ4-1", "sequence": { "sequence": "MRPLLLLLLATAHGLDKLSYKPTLVGGNVEGRMTGSTFVLEQPRCVFDSYSTANIWLVVATREGMDAFNDSAQPGMPEWSFQRFPTNTSAYLTLGAMQYHYGCPKPDRELTVLRVGSETDCADNISVPNCNGPLPGPGPYWVKFLALNGSEPTATTEWSGPITLKTAREPQSIPGTGGARSGAMIAITAILSVLLAILLAALLATLCSSEACGVGSFRPDAASIRRYNTHHVYDQPAARL", "length": 240, "header": "tr|A0A8V1AAZ4-1|A0A8V1AAZ4_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN=UPK3BL PE=4 SV=1 CANONICAL=A0A8V1AAZ4-1" }, "locus": { "chromosome": "19", "start_pos": 4664030, "end_pos": 4662501, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070458.1", "url": "https://www.ensembl.org/id/ENSGALT00010070458.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043149.1", "url": "https://www.ensembl.org/id/ENSGALP00010043149.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:417514", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417514", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A2CE76-1", "protein_name": "Uroplakin-3b precursor", "gene_name": "upk3b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNTHNAIRLVSLLSIWMLAAQGQIFQPQLAPANFLGRITSNTVILQQPYCVFTQTCPGCEIWLVAALSTGTGNFNALVNISSPISLSVSPYPTAFLPSSAQFFLTRVGPLANFPCNTAPAFPYFTVGADGICTGINCNGVLPVGSIVSFRYLLIDPSNYTVVNMTNWGGPFNLTTLLSYQTINDGLSARSGAMVVITTLLCVAVALLLLVFFIMLCVSCCGKKDGKTVTVMSSIRIPRYDTHNLKEHVHPYDNQAYEPDAKNYSRSQTLPKSPVRK", "length": 276 }, "evidence": [ { "id": "A0A8V1AAZ4", "url": "https://omabrowser.org/oma/group/A0A8V1AAZ4/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A6QQ85-1", "protein_name": "Uroplakin-3b-like protein 1", "gene_name": "UPK3BL1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGLGRGQSPLLMALLLLLACLQMGMSLERISYVPQLSSATLAGRLTQSTFTLEQPRGQFSHPSISDSDAIWLVVAHSNATQKFTAPQKVEDTPVPADFPQRGYYLTLRASRALYPGGPPSNQLRVLRVGNDTRCSPRTRGCNRPLPGPGPYRVKFLVMSDRGPMAETEWSSETRLQQAEVLQAAPGPQTAGTVVIIAILSVLLAVLLAALLALLIFTWYDTCGSTPISGPGELVFVRKYDTHHMSRPSTVGGS", "length": 253 }, "evidence": [ { "id": "A0A8V1AAZ4", "url": "https://omabrowser.org/oma/group/A0A8V1AAZ4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "B0FP48-1", "protein_name": "Uroplakin-3b-like protein 1", "gene_name": "UPK3BL1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDNSWRLGPAIGLSAGQSQLLVSLLLLLTRVQPGTDVAAPEHISYVPQLSNDTLAGRLTLSTFTLEQPLGQFSSHNISDLDTIWLVVALSNATQSFTAPRTNQDIPAPANFSQRGYYLTLRANRVLYQTRGQLHVLRVGNDTHCQPTKIGCNHPLPGPGPYRVKFLVMNDEGPVAETKWSSDTRLQQAQALRAVPGPQSPGTVVIIAILSILLAVLLTVLLAVLIYTCFNSCRSTSLSGPEEAGSVRRYTTHLAFSTPAEGAS", "length": 263 }, "evidence": [ { "id": "A0A8V1AAZ4", "url": "https://omabrowser.org/oma/group/A0A8V1AAZ4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "D3ZXT5-1", "protein_name": "Uroplakin 3B like 1", "gene_name": "Upk3bl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGPHRKQSMLLLPLLVLVTCVQPGTGLESINYVPQLPSATLEGRLTQSTFTLEQPLDQFKNVNLSDADPIWLVVARSDMPPPAAQNFTAPRKVEDRHAPAHFDDNGYYLTLRASRVHYKGSQNDSRLPVLRVGNDNNCSVRSQGCNSPLPGPGPYRVKFLAMNAKGPVAETLWSKDIYLQQAQTFRGAPGSQSKGTVVIIAFSSILLAILLAVFLMLVISACCSSTSVSSPEEQVRMRRYHTHHVGSLPAERSS", "length": 254 }, "evidence": [ { "id": "A0A8V1AAZ4", "url": "https://omabrowser.org/oma/group/A0A8V1AAZ4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9D701-1", "protein_name": "Uroplakin-3b-like protein 1", "gene_name": "Upk3bl1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGPHGKQSVLRMPLLLLLTCVQSGTGLESINYAPQLLGATLEGRLTQSTFTLEQPLGQFKNVNLSDPDPIWLVVAHSNAAQNFTAPRKVEDRHAPANFDRNGYYLTLRANRVHYKGGQPDSQLRVLRVGNDNNCSLESQGCNSPLPGAGPYRVKFLAMSAEGPVAETLWSEEIYLQQAQTFREAPGSQGKGTVVIIAFLSILLAILLVVFLVLVISACLSTSGSSPEEQVRMRHYHTHHMGSLRAERSS", "length": 249 }, "evidence": [ { "id": "A0A8V1AAZ4", "url": "https://omabrowser.org/oma/group/A0A8V1AAZ4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAZ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAZ4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 124, "end_pos": 126, "annotation": "n_glycosylation_sequon" }, { "start_pos": 148, "end_pos": 150, "annotation": "n_glycosylation_sequon" }, { "start_pos": 69, "end_pos": 71, "annotation": "n_glycosylation_sequon" }, { "start_pos": 87, "end_pos": 89, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 124, "end_pos": 126 }, { "start_pos": 148, "end_pos": 150 }, { "start_pos": 69, "end_pos": 71 }, { "start_pos": 87, "end_pos": 89 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": 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"o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AB02-1", "uniprot_ac": "A0A8V1AB02", "uniprot_id": "A0A8V1AB02_CHICK", "mass": { "chemical_mass": 8762.0, "monoisotopic_mass": 8762.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "A0A8V1AB02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB02/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AB02", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB02" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB02", "locus": {} } ], "crossref": [ { "id": "A0A8V1AB02", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AB02", "database": "AlphaFoldDB", "categories": [] }, { "id": "A0A8V1AB02", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB02", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AB02-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB02-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "HHPWGDATSFCSTKHLKQGGNGTFQPSRVKLSIHCQHILPEYERPICGGKPQPSVMATYLTSGHTHMEATPLPYRVPIV", "length": 79, "header": "tr|A0A8V1AB02-1|A0A8V1AB02_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1AB02-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AB02-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB02/entry#A0A8V1AB02-1", "sequence": { "sequence": "HHPWGDATSFCSTKHLKQGGNGTFQPSRVKLSIHCQHILPEYERPICGGKPQPSVMATYLTSGHTHMEATPLPYRVPIV", "length": 79, "header": "tr|A0A8V1AB02-1|A0A8V1AB02_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1AB02-1" }, "locus": { "chromosome": "2", "start_pos": 3733898, "end_pos": 3733414, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010062427.1", "url": "https://www.ensembl.org/id/ENSGALT00010062427.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038599.1", "url": "https://www.ensembl.org/id/ENSGALP00010038599.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 21, "end_pos": 23, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 21, "end_pos": 23 } ] }, "class_list": [], 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"total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AB13-1", "uniprot_ac": "A0A8V1AB13", "uniprot_id": "A0A8V1AB13_CHICK", "mass": { "chemical_mass": 47355.0, "monoisotopic_mass": 47355.0 }, "refseq": { "ac": "XP_024999870", "name": "Ig-like V-type domain-containing protein FAM187A", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024999870" }, "gene_names": [ { "name": "FAM187A", "type": "recommended", "evidence": [ { "id": "A0A8V1AB13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB13" } ] }, { "name": "FAM187A", "type": "synonym", "evidence": [ { "id": "XP_024999870", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024999870" } ] } ], "protein_names": [ { "name": "Family with sequence similarity 187 member A", "type": "synonym", "evidence": [ { "id": "A0A8V1AB13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB13/entry#names_and_taxonomy" } ] }, { "name": "Ig-like V-type domain-containing protein FAM187A", "type": "synonym", "evidence": [ { "id": "XP_024999870", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024999870" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052558.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_024999870.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_024999870", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024999870" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AB13", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB13" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FAM187A", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB13", "locus": { "chromosome": "27", "start_pos": 927260, "end_pos": 926016, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010026363", "url": "https://www.ensembl.org/id/ENSGALG00010026363" } ] } } ], "crossref": [ { "id": "A0A8V1AB13", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AB13", "database": "AlphaFoldDB", "categories": [] }, { "id": "101747521", "url": "https://www.ncbi.nlm.nih.gov/gene/101747521", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013106", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013106", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039311", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039311", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:101747521", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:101747521", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "AWDKDST", "url": "https://omabrowser.org/oma/group/AWDKDST/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AB13", "url": "https://www.orthodb.org/?gene=A0A8V1AB13", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR32178", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR32178", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR32178:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR32178:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07686", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07686", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_024999870", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024999870", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AB13", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB13", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AB13-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB13-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEMGLLGAVLLLCMADVLHSFAIEEKEDIFRRMVCPAFLMFDNAAYLADMTFELPCNCKPEEVSNVVWYFQKNMGGHETTVLTDFSGNMVLDSGHIHVGSDVLKRFTIRMFSLIIFRAQVSDSGHYMCGTKKGDFFYGYDVDVQPTKHITVAFLDIGQHVQDDYTGKAFSLFTTFWDWTKCDRCGVRGEQRRIGLCYVQSARLHPRYRTVLPNVTSCGSRAVPARLQRSGRRWKPEVAVRSCMAPCPQENNPQEGVQAISNVIYKLGQKPWLPRVPTQFYRHPLGRDLVIACPGARPEHAVAWDKGSVRLYRSRYLVGVNKTMRVFIDHGNHLHIRRVRFSDRGTYFCWREGKLAAGLRLRVSYEAQRRRSLDDPETIYIIKAIGVSYVLVGAIFIGVHLCRCCSRVLRYSVRV", "length": 414, "header": "tr|A0A8V1AB13-1|A0A8V1AB13_CHICK Isoform 1 of Family with sequence similarity 187 member A OS=Gallus gallus OX=9031 GN=FAM187A PE=3 SV=1 CANONICAL=A0A8V1AB13-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AB13-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB13/entry#A0A8V1AB13-1", "sequence": { "sequence": "MEMGLLGAVLLLCMADVLHSFAIEEKEDIFRRMVCPAFLMFDNAAYLADMTFELPCNCKPEEVSNVVWYFQKNMGGHETTVLTDFSGNMVLDSGHIHVGSDVLKRFTIRMFSLIIFRAQVSDSGHYMCGTKKGDFFYGYDVDVQPTKHITVAFLDIGQHVQDDYTGKAFSLFTTFWDWTKCDRCGVRGEQRRIGLCYVQSARLHPRYRTVLPNVTSCGSRAVPARLQRSGRRWKPEVAVRSCMAPCPQENNPQEGVQAISNVIYKLGQKPWLPRVPTQFYRHPLGRDLVIACPGARPEHAVAWDKGSVRLYRSRYLVGVNKTMRVFIDHGNHLHIRRVRFSDRGTYFCWREGKLAAGLRLRVSYEAQRRRSLDDPETIYIIKAIGVSYVLVGAIFIGVHLCRCCSRVLRYSVRV", "length": 414, "header": "tr|A0A8V1AB13-1|A0A8V1AB13_CHICK Isoform 1 of Family with sequence similarity 187 member A OS=Gallus gallus OX=9031 GN=FAM187A PE=3 SV=1 CANONICAL=A0A8V1AB13-1" }, "locus": { "chromosome": "27", "start_pos": 927257, "end_pos": 926016, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010064154.1", "url": "https://www.ensembl.org/id/ENSGALT00010064154.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039444.1", "url": "https://www.ensembl.org/id/ENSGALP00010039444.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:101747521", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:101747521", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A9J7H366-1", "protein_name": "Ig-like V-type domain-containing protein FAM187A", "gene_name": "Fam187a", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSLAHTTVLLWAWGSLQAFEIVEKENIFQKTPCPAFLMFDNAAYLADMSFELPCHCKPEDVSAVVWYYQKHLGSSHTTVLTDFDGRLLTEAAHVRAGSSMLVRFSIRMFSLLVFRAQPEDSGLYFCGTRKGDYFYAYDVDIQSSEGMVATFKDRGQEPLPDEYFGSLHVFTTFWEWTPCDRCGVHGEQWRLGLCYLQNPDLSPRYLKTLPDVVSCGSRAVPRKLWIRTRYHTPELLIQSCLVSCEKRNQIRKGMLTIYNYVSKMGSRPWLPQVPIQFHQQRLGHGLIISCPGARPEHAVAWDKDRQPLYRTQYLKGVNRSMRVFIDHGNHLHIRFTQLSDRGIYYCWRQGLRIAGFRLGVTSRGRYPASLSDPETRSAVELTLIGYLLITAIFVTIHVCRCCCYSFRCCPNFSTHALLQL", "length": 420 }, "evidence": [ { "id": "A0A8V1AB13", "url": "https://omabrowser.org/oma/group/A0A8V1AB13/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A7E3C4-1", "protein_name": "Ig-like V-type domain-containing protein FAM187A", "gene_name": "FAM187A", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNLAHTTVLLWAWGSLQAFEIVEKENIFQRTPCPAFLMFDNAAYLTDMSFELPCPCKPEEVSAVVWYYQKHLGSSHTKVLTDFDGRVLTEAAQVRVGSDMLVRFSIRMFSLLVFRAQPEDSGLYFCGTRKGDYFYAYDVDIQSSEGMVATFKDQGQEPLEDEYHGSLRVFTTFWEWTPCDRCGVRGEQWRIGLCYLQSPDLSPRYRKILPNVVSCGSRAVPRQLRAKASDHNPELLVRSCLMPCEKKKKVQEGVMAIFNYVSKVGSRPWLPQVPIQFHQQRLGHGLIISCPGARPEHAVAWDKDHQYLYRTQYLKGVNGSMRVFIDHGNHLHIRFTQLEDRGIYYCWRQGERIAGFRLGVTSPGRYPVSFSDPETRAALGLILIGYMLITVIFISIHLCRCCCYLFRFCPNFSPRLSRPQL", "length": 421 }, "evidence": [ { "id": "A0A8V1AB13", "url": "https://omabrowser.org/oma/group/A0A8V1AB13/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1RR01-1", "protein_name": "Family with sequence similarity 187 member A", "gene_name": "FAM187A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MNPAHTTVLLWVWGSLQAFEIVEKENIFQRTPCPAFLMFDNAAYLADMSFELPCHCKPEEVAAVVWYYQKHLGSSHTKVLTDFDGRVLTEAAQVRVGSDMLVRFSIRMFSLLVFRAQPEDSGLYFCGTRKGDYFYAYDVDIQSGEGMVATFKDQGQEPFADEYHGSLRVFTTFWEWTPCDRCGVRGEQWRIGLCYLQSPDLSPRYRRTLPDVVSCGSRAVPRPLRAKVSDHTPELLVRSCLVPCETTKIQKGVMAIFNYVSKVGSRPWLPQVPIQFHQQRLGHGLIISCPGARPEHAVAWDKDRQYLYRTQYLRGVNRSMRVFIDHGNHLHIRFTQLEDRGIYYCWRQGERIAGFRLGVTQRGRYPASFSDPETRAALRLTLIGYLLITAVFVTVHLCRCCCHLFRCWPDLSP", "length": 413 }, "evidence": [ { "id": "A0A8V1AB13", "url": "https://omabrowser.org/oma/group/A0A8V1AB13/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q6AXV7-1", "protein_name": "Ig-like V-type domain-containing protein FAM187A", "gene_name": "Fam187a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRLAPTTVLLWAWGSLQAFEIVEKENIFQRTPCPAFLVFDNTAYLADMSFELPCHCKPEDVSAVVWYYQKYLGSSHTTVLTDFDGRLLTEAAHVRVGSSMLARFSIRMFSLLVFRAQPEDSGLYFCGTRNGDYFYAYDVDIQSHKGMVASFRDKGQEPLPDEYYGSLHVFTTFWEWTPCDRCGVRGEQWRFGLCYLQNPNLSPRYIKTLPDVVSCGSRAVPWKLHLKTKYHTPELLIQSCLVSCKKNKMGEGILAIYNYVSKLGGRPWVPQVPIQFHQQRLGHGLIISCPGARPEHAVAWDKDSQPLYRTQYLKGVNRSMRVFIDHGNHLHIRFTQLSDRGIYYCWRQGLKIAGFRLGVTSRGRYPASLSDPETRTAVELTLIGYLLIAVVFVTIHLCRCCCQSRCCPNFSAQTLLQL", "length": 418 }, "evidence": [ { "id": "A0A8V1AB13", "url": "https://omabrowser.org/oma/group/A0A8V1AB13/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9D3R5-1", "protein_name": "Ig-like V-type domain-containing protein FAM187A", "gene_name": "Fam187a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSLAHTTVLLWAWGSLQAFEIVEKESVFQRTPCPAFLVFDNAAYLADMSFELPCHCKPEDVSAVVWYYQKHLGSKRTTVLTDFDGRLLTEAAHVRVGSSMLVRFSIRMFSLLVFRAQPEDTGLYFCGTREGDYFYAYDVDIQSNKEIVASFKDMAQEPLPDEYYGALHVFTTFWEWTPCDRCGVRGEQWRFGLCYLQYPDLSPRYIKTRSAVVSCGSGAVPWKLHLQTKYHTPELQFQSCLVSCQKRNKTRKGVLAIYSYVSKLGSRPWVPQVPIQFHQQRLGHGLIISCPGARPEHAVAWDKDNQPLYRAQYLKGVNRSMRVFIDHGNHLHIRFTQLSDRGIYYCWLQGLKIAGFRLGVITRGRYPASLSDPETRTAIELTLMGYLLITIFFITIHLCRCCCQSRCCPNFSAQTLL", "length": 417 }, "evidence": [ { "id": "A0A8V1AB13", "url": "https://omabrowser.org/oma/group/A0A8V1AB13/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AB13", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB13" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 213, "end_pos": 215, "annotation": "n_glycosylation_sequon" }, { "start_pos": 320, "end_pos": 322, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AB13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB13" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 270, "end_pos": 348, "start_aa": "Pro", "end_aa": "Cys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 213, "end_pos": 215 }, { "start_pos": 320, "end_pos": 322 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AB20-1", "uniprot_ac": "A0A8V1AB20", "uniprot_id": "A0A8V1AB20_CHICK", "mass": { "chemical_mass": 334979.0, "monoisotopic_mass": 334979.0 }, "refseq": { "ac": "NP_001376459", "name": "zinc finger ZZ-type and EF-hand domain-containing protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376459" }, "gene_names": [ { "name": "ZZEF1", "type": "recommended", "evidence": [ { "id": "A0A8V1AB20", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB20" } ] }, { "name": "ZZEF1", "type": "synonym", "evidence": [ { "id": "NP_001376459", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376459" } ] } ], "protein_names": [ { "name": "Zinc finger ZZ-type and EF-hand domain containing 1", "type": "synonym", "evidence": [ { "id": "A0A8V1AB20", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB20/entry#names_and_taxonomy" } ] }, { "name": "zinc finger ZZ-type and EF-hand domain-containing protein 1", "type": "synonym", "evidence": [ { "id": "NP_001376459", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376459" } ] }, { "name": "zinc finger, ZZ-type with EF hand domain 1", "type": "synonym", "evidence": [ { "id": "NP_001376459", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376459" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000323.1. On Oct 5, 2021 this sequence version replaced NP_001376459.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001376459", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376459" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AB20", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB20" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ZZEF1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB20", "locus": { "chromosome": "19", "start_pos": 3747825, "end_pos": 3693681, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029166", "url": "https://www.ensembl.org/id/ENSGALG00010029166" } ] } } ], "crossref": [ { "id": "cd02249", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02249", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd02343", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02343", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd08667", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08667", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "417496", "url": "https://www.ncbi.nlm.nih.gov/gene/417496", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000433", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000433", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002048", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002048", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004939", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004939", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040099", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040099", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041986", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041986", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043145", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043145", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047052", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047052", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "RPTPPCE", "url": "https://omabrowser.org/oma/group/RPTPPCE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AB20", "url": "https://www.orthodb.org/?gene=A0A8V1AB20", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22772", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22772", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22772:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22772:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00569", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00569", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03256", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03256", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001376459", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376459", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AB20", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB20", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AB20-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB20-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGTAASHSSEEEEEGAEEGMEAAAQPGDPFPAASPAPPLPPAEVLLEQARLREATARLREAALPESLVSRHHGALVRWLEERLSRGDEAVSLEQFCEVLESVSRLTAGSRGESEEAFAQFDAEGDGTVDVENMLEALKNSSGANLQGELSHVIRQLQACSLVPGFIDIFSESKERLGLHASMILRFLHRNRISSTAIPYPVLEYFNNICMMRSSVLKDSLDRLLLKEREYPSDLNGNEESDKLKSVTKCYTHIETSSNSADIDKMTNGETTSFWQSDGSARSHWIRLKMKPDVVLRHLSIAVAANDQSYMPQQVTVAVGRNASSLQEVRDVHIPSNITGYVTLLENANISQMYVQINIKRCLSDGCDTRIHGLRAIGYQRVKKVGVSVCDASAIWYWSLLTSLVTASMETNPAFVHTILQNTQKALQHMPPLSLTPSSTDFSSFLSPNVLQEVDSFLIRITSCCTTPDVELTLLAFALARGSVAKVISSLCTITDHLDTPYKASSLIASMATVRQNLLYKYGKPLRLTLQACDVKGKEDKSGPENLLVEPWTGDGFLTETGKTRASIILSTGTESSFQVTQIRIKVRRGAIGAQCGLVFAYNSASEKFHAEEHFKRFESYDKWKLKDFKQFLKNRSGSSSDELGDDDPIGWFEVEEEWDEVDVRMQQCRVAQYLMIKFLCTRQDTAERLGVQGLNVLGYLRPMREEPSRSMHCLQCRKTDDETVCGTTLLLKTLHFIQQLAQDLVQQKESGLKCKSYLDFTDLDLQLFWNFYNKLHQNPREECIFAQTLLLQLLQSCFSVFTGDNKTSKPQETLQGRTPGHTKAAEDLYRHLCEVVDMGDTNFMPVKMLKQEVKNTLLSGAAIFFPDRQTRRNQLFAMMKNITEQEHKQSVHLAFRSLCTHFSDQDPGGLLLLPEKGVSANFDISEVLSVMDTLLLVAARECEMMMLDVAQQESGTVLSSLFWSVQGSLLSWCYLQLKGSDSSAKDLAVEILKNYVGQFLTNVRMILQSLLSQYSGKTIVEKISNSVFAMATRQLVIFLLDFCTLDIPYCTLLQEFSTLVEPLKKLCSEPHKMEIESWQQEQPVVLRTWTVESPHNYENNCHEVSVFLCHGASYFEVEFDEKCETERRYDYLEFTDARGAKTRYDTKVGTEKWPKKVTFKAGPRLQFLFHSDSSNNEWGYKFTVTAYGLPDVAVSWGLDLQLLVCRLMGRLASRSMALKSQRELGSEADLPPLKVTSVLNSPLWKPVFRHQMCPEAEPGASETSRGHQDKKEARSSHQDDCRNFLIDFARSDPAQDFSGQKSELFKGLVQTCRKQTPKTDTVAGSTVDRAVNSTFAALVYLTPALYEKLQKYVNSGGKVPLSDEFAQVYSLADSIRIWMLEMKQKSLMGRGNDTEEKQSTEASEVNPETLAKLCMQKSLLLLNFLPVRAKTKGSTSDSLEAQDGDNVHQYVNDRNQRKSSVVETDFQAAHSSSSSGVTRSVSVEGEQTTQSDTKIKQISDPLQTEEVSAFHSKPSENTALQQEDVPSPPSTPTRKSQFSRGRLRLLSFRSMEEPRAVPTLKEKYPILKSILDFIKDQSLSHESVLKVLALRKSQGQNILEVLRTIRRCLDSLGQPHCFHPPCVLFLLELLACQKDFTNYFGNLEGCGAALHKEIRESYYQLVLFLVNSVKGFSAINDRSLLPALSCVQTTLLHLLDMSWEPTDLSFFVEIQLPQLLMATSQENISIHDSVICQWSEEDEIADYKQNCEWMDECQDIMFESWYEKIAQADPEKQRKMHMFVARYCDLLNVDISCDGCDEIAPWHRYRCLQCNDMDLCKTCFLGGVKPEGHEDDHEMVNMEYACDHCQGVIIGRRMNCNVCDDFDLCYGCYSAKKYSDSHLPTHSITVYPMMTIRISDRQRLIQPYVHNYSWLLFAALTLYSADLANGEEVEGEKLDSQVLSHARILQHQCIQLIGDCLMKAQQGKGLKNLALLCMLPEGESLSENDTASVSPPTDGAPKSHTGDKAGKGKDEKPSTGSFMHSNGKGETLNEIQSPAGDKVQKHGSESDRNAVSAKKAVLRQESELSMEDNITPTVDDCISEDSAQKQAEKVLIPSQEQVFAECSQKRILGLLAAMLPPFKSGSTMSLINLEQILPLMFQVVISNAGHLNETYHLTLGLLGQLILRLKPAEVDAAVAKVLSTKHSLFAAGDPSTVPEGWKTTHLLFSLGAVCLDSRVGLDWASSMADILRSLNSSAQWHSVIAAFTDHCIKQLPFQLKHTNIFTLLVLVGFPEVLCMGTRSVYMDNANEPHNVIILKHFTEKNRAVVVDIKTRKRKTVKDYQLIQKCEQEGSDSQAQLRQYLQHFVLICTHLLQTTIDSSYAEAVEATWVLSLALKGLYRTLKIHGFQEVQDAFLHSGLLKLLVKKCSKGTGFSKTWLLRDLEILSIMLYSSKKEISSLAEREDTELEEREQDQDVEQSIVGPADVEQNKLDPLEGLDEATKICFLMTHDALNAPLHILRAMYELQMKRTESFFLEVQKRFDGDVITTDERIRTLAQKWQPSKRLRLEEQSSKAVDTDMIILPCLSKPVLCDKATEETNPVAQKLITNTESDLQLSYAKQRRTKSSILLHKELDSRSKKAVRDYLYRVNEATAVLYARHVLASLLAEWPDDVAINEEVLDLSGPAHMTYILDMLMQLEEKQLWEKILQKVLLGCNESMLGTMALTACQFMEEPGMAVQVRESKHPYNNNTNFEDKVQIPGAIYLSIKFDSQCNTEEGCDELLMSSSSDFQQDRHSFSGSPQKWNDFELPGDTLYYRFTSDMSNTEWGYKFTVTAGHLGRFQTGFEILKQMLSEERVIPHLPLARIWEWQVGVACRQTGHQRLKAIHLLLKIVQCSAQRDCDLTLLKPLWQLFTHMENNICHDVTKPGILLPLHRALAELFFVTENRVTELGSLQEYLLALNSEDHLHRCTAQALRNIAAISLAINYPNKSTSFWNV", "length": 2974, "header": "tr|A0A8V1AB20-1|A0A8V1AB20_CHICK Isoform 1 of Zinc finger ZZ-type and EF-hand domain containing 1 OS=Gallus gallus OX=9031 GN=ZZEF1 PE=1 SV=1 CANONICAL=A0A8V1AB20-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AB20-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB20/entry#A0A8V1AB20-1", "sequence": { "sequence": "MGTAASHSSEEEEEGAEEGMEAAAQPGDPFPAASPAPPLPPAEVLLEQARLREATARLREAALPESLVSRHHGALVRWLEERLSRGDEAVSLEQFCEVLESVSRLTAGSRGESEEAFAQFDAEGDGTVDVENMLEALKNSSGANLQGELSHVIRQLQACSLVPGFIDIFSESKERLGLHASMILRFLHRNRISSTAIPYPVLEYFNNICMMRSSVLKDSLDRLLLKEREYPSDLNGNEESDKLKSVTKCYTHIETSSNSADIDKMTNGETTSFWQSDGSARSHWIRLKMKPDVVLRHLSIAVAANDQSYMPQQVTVAVGRNASSLQEVRDVHIPSNITGYVTLLENANISQMYVQINIKRCLSDGCDTRIHGLRAIGYQRVKKVGVSVCDASAIWYWSLLTSLVTASMETNPAFVHTILQNTQKALQHMPPLSLTPSSTDFSSFLSPNVLQEVDSFLIRITSCCTTPDVELTLLAFALARGSVAKVISSLCTITDHLDTPYKASSLIASMATVRQNLLYKYGKPLRLTLQACDVKGKEDKSGPENLLVEPWTGDGFLTETGKTRASIILSTGTESSFQVTQIRIKVRRGAIGAQCGLVFAYNSASEKFHAEEHFKRFESYDKWKLKDFKQFLKNRSGSSSDELGDDDPIGWFEVEEEWDEVDVRMQQCRVAQYLMIKFLCTRQDTAERLGVQGLNVLGYLRPMREEPSRSMHCLQCRKTDDETVCGTTLLLKTLHFIQQLAQDLVQQKESGLKCKSYLDFTDLDLQLFWNFYNKLHQNPREECIFAQTLLLQLLQSCFSVFTGDNKTSKPQETLQGRTPGHTKAAEDLYRHLCEVVDMGDTNFMPVKMLKQEVKNTLLSGAAIFFPDRQTRRNQLFAMMKNITEQEHKQSVHLAFRSLCTHFSDQDPGGLLLLPEKGVSANFDISEVLSVMDTLLLVAARECEMMMLDVAQQESGTVLSSLFWSVQGSLLSWCYLQLKGSDSSAKDLAVEILKNYVGQFLTNVRMILQSLLSQYSGKTIVEKISNSVFAMATRQLVIFLLDFCTLDIPYCTLLQEFSTLVEPLKKLCSEPHKMEIESWQQEQPVVLRTWTVESPHNYENNCHEVSVFLCHGASYFEVEFDEKCETERRYDYLEFTDARGAKTRYDTKVGTEKWPKKVTFKAGPRLQFLFHSDSSNNEWGYKFTVTAYGLPDVAVSWGLDLQLLVCRLMGRLASRSMALKSQRELGSEADLPPLKVTSVLNSPLWKPVFRHQMCPEAEPGASETSRGHQDKKEARSSHQDDCRNFLIDFARSDPAQDFSGQKSELFKGLVQTCRKQTPKTDTVAGSTVDRAVNSTFAALVYLTPALYEKLQKYVNSGGKVPLSDEFAQVYSLADSIRIWMLEMKQKSLMGRGNDTEEKQSTEASEVNPETLAKLCMQKSLLLLNFLPVRAKTKGSTSDSLEAQDGDNVHQYVNDRNQRKSSVVETDFQAAHSSSSSGVTRSVSVEGEQTTQSDTKIKQISDPLQTEEVSAFHSKPSENTALQQEDVPSPPSTPTRKSQFSRGRLRLLSFRSMEEPRAVPTLKEKYPILKSILDFIKDQSLSHESVLKVLALRKSQGQNILEVLRTIRRCLDSLGQPHCFHPPCVLFLLELLACQKDFTNYFGNLEGCGAALHKEIRESYYQLVLFLVNSVKGFSAINDRSLLPALSCVQTTLLHLLDMSWEPTDLSFFVEIQLPQLLMATSQENISIHDSVICQWSEEDEIADYKQNCEWMDECQDIMFESWYEKIAQADPEKQRKMHMFVARYCDLLNVDISCDGCDEIAPWHRYRCLQCNDMDLCKTCFLGGVKPEGHEDDHEMVNMEYACDHCQGVIIGRRMNCNVCDDFDLCYGCYSAKKYSDSHLPTHSITVYPMMTIRISDRQRLIQPYVHNYSWLLFAALTLYSADLANGEEVEGEKLDSQVLSHARILQHQCIQLIGDCLMKAQQGKGLKNLALLCMLPEGESLSENDTASVSPPTDGAPKSHTGDKAGKGKDEKPSTGSFMHSNGKGETLNEIQSPAGDKVQKHGSESDRNAVSAKKAVLRQESELSMEDNITPTVDDCISEDSAQKQAEKVLIPSQEQVFAECSQKRILGLLAAMLPPFKSGSTMSLINLEQILPLMFQVVISNAGHLNETYHLTLGLLGQLILRLKPAEVDAAVAKVLSTKHSLFAAGDPSTVPEGWKTTHLLFSLGAVCLDSRVGLDWASSMADILRSLNSSAQWHSVIAAFTDHCIKQLPFQLKHTNIFTLLVLVGFPEVLCMGTRSVYMDNANEPHNVIILKHFTEKNRAVVVDIKTRKRKTVKDYQLIQKCEQEGSDSQAQLRQYLQHFVLICTHLLQTTIDSSYAEAVEATWVLSLALKGLYRTLKIHGFQEVQDAFLHSGLLKLLVKKCSKGTGFSKTWLLRDLEILSIMLYSSKKEISSLAEREDTELEEREQDQDVEQSIVGPADVEQNKLDPLEGLDEATKICFLMTHDALNAPLHILRAMYELQMKRTESFFLEVQKRFDGDVITTDERIRTLAQKWQPSKRLRLEEQSSKAVDTDMIILPCLSKPVLCDKATEETNPVAQKLITNTESDLQLSYAKQRRTKSSILLHKELDSRSKKAVRDYLYRVNEATAVLYARHVLASLLAEWPDDVAINEEVLDLSGPAHMTYILDMLMQLEEKQLWEKILQKVLLGCNESMLGTMALTACQFMEEPGMAVQVRESKHPYNNNTNFEDKVQIPGAIYLSIKFDSQCNTEEGCDELLMSSSSDFQQDRHSFSGSPQKWNDFELPGDTLYYRFTSDMSNTEWGYKFTVTAGHLGRFQTGFEILKQMLSEERVIPHLPLARIWEWQVGVACRQTGHQRLKAIHLLLKIVQCSAQRDCDLTLLKPLWQLFTHMENNICHDVTKPGILLPLHRALAELFFVTENRVTELGSLQEYLLALNSEDHLHRCTAQALRNIAAISLAINYPNKSTSFWNV", "length": 2974, "header": "tr|A0A8V1AB20-1|A0A8V1AB20_CHICK Isoform 1 of Zinc finger ZZ-type and EF-hand domain containing 1 OS=Gallus gallus OX=9031 GN=ZZEF1 PE=1 SV=1 CANONICAL=A0A8V1AB20-1" }, "locus": { "chromosome": "19", "start_pos": 3744892, "end_pos": 3693843, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070483.1", "url": "https://www.ensembl.org/id/ENSGALT00010070483.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043174.1", "url": "https://www.ensembl.org/id/ENSGALP00010043174.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8M9P8V5-1", "protein_name": "Zinc finger ZZ-type and EF-hand domain-containing protein 1", "gene_name": "zzef1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGNAESGCGAGSGDEEDVETESPVFAEGSPASAATGTRAGSGGGGGGGGAGGAAAAGSAGPGRSGRGSANPPAPSHGLPTPEALLEQVKLREAAARMSDSWVAISESVLARNESALVRWLEERLSRGEESVTLEQFCEMLESRDAARDECEEAFGQFDAEGDGIVDVENMLMALRNSNGANLQGELSHVIRQLQACSLTPGFVDIFSKSKDRLKAHASKILKFLHRNRIPSNVIPFPVLDGYNSICTMRTSVVQDFLDYLLQKEKDLDIQYRAELNHDPDVDKVKVVTQCFSFIEASSNNTDVNKLTNGETVSFWQSDGSARSHWIRLKMKPDIVLRRLAIAVASNDHSYMPQLVSIAVGKNRRSLQEIRDVRIPSNITGYVPLLENANISHPYIQINIKRCLSDGCDTRIHGLKTMGYQITKSKEVSVSDASAIWYLSLLTSLVTASMETNPVLAQTVLQSTQKALQHMPPLSLTPSSTEFPKFFSANILEEVDGFLLRIANCCVSPEAELTLLAFALARGSVAKVLISLSGICGHLDSEYRASSLLASMSSVRLRLLHRNGKPLQLHLMACDVKSKEEKSGPENMLTEPNTGDGFLTENGKRKASVILSTENQSCFQVTQIKIKVRKGAIGAKCGLVFAYNDCEVFDADKHFKRFKKYDSWDYKDYKEFVQDSTRITESSEEEPIGWFEVEEDWNDVDIKLQQCRVSKFLMVKFLCARQDTAERLGVQQLIFSGYLCPDSERMEDVEDLSAQAEGSDSGLVTGLALMKKTLYFIQQLTRDMDVSLSKQKTLLDFSDLNLLLFWDFYRKLRSIEGEEAIKTRVLLLQLLQNCFPMLPSPTESQPSDLSASASASPSGSSDVDPAEAVGELCRHLCQVVDGPEGETAAEKALRKEAVKAILNGAAIFYPDKQSRRDKLFHMMKNITEENQPESVKLTFESLCSYFSDQDPKGLLMLPPKGAPSDFDISPVLSVMDTLLIVASRECEVLMSESSGGSIWRVLLSLFWALQGSLLSWCFLQLKGGTATSSDLAREILLKYVEQFLSGTRDILIPLTKSFSGADIMKKLSGSILAMATRQLTIFLLELCALDIPHCVLLKRFYPISDLLKNMSSDTDDIFSKVDLEGCQQPQQPVVLRTWQMESPHNYENSRHETTVFVCPGATSFEVEFDARCETEKRYDYLEFTDARGGKVRYDMKVGTEKWPKKVTFKAGPQLQFLFHSDSSNNEWGYKFTVTAYGLPDVTVSWTSDLQLLVSRLMGRLASRTMALKSPYEIRGVKELPATLMNHILSCPLWKPVFRHGLSGLPGEQKLALASPEASQEDPAPLGDELVEFLKEFARWDPSQDSSDGRTELMRTLLVNCKKQLIRNEIASGLKVDQAVNAIWAAMVYHTPALHPCLKSFVAKNGQSGLSEDLVQVYTLADGIRTWMLEMKQRYLMGKMNGVEEKDEGQNEVTMESLAEVCISRSLFLFQFSPSGGTSAPQDQETSRPEDIACAAPLLRSISTSEGDFQPSPSLSISQTPHGAEAVTSPVSASRERTQDQSFSASGDAGASGSISSQGATGSSESLQSQTGEPLSPSVFPRKAPFSRGRLRLLSLRSMEEPRMAPPVKERFPILKHILSFMKDMVINESSVLQTLALKKAQAVSVCEVLELVQQCILTLGKPHLFQAPCILFLQELLACQKDFTNYFSQLVGSGQEMRERVRHSYHQLVLMLVEAVQGFSALNEKVLLPALSCVQTCLLHLLDMSWEAEDLSLFLDIKLPDLLLAMSQENISVHDIAISQWTEEDEIADYERNCEWMDECLDGMFEKWFDKISQASVEDKRKMHMFIARYCDLLNVEISCDGCERIAPWHRYRCLQCTDMDLCKTCFLSGAKPEGHEDDHEMVNMEYACDHCQGLIVGSRINCNVCEDFDLCFGCYNAKKYPDSHLPTHRITVYPMVTIRISDRHRLIQPYIHNYSWLLFAALALFTSELISEKAQDGESLDDVTLGNASALQTQCFDIIKECLLKGQTGKGLRASALLSLLSSNESATVSELCPATAGSSQDISSTDTSSLPSSTTAICSPPLPRDRGGGEGDEKRRRKLVSQDTSDSSCASQTPSVSSEDTLSPGVRGSESSGDTITSPTSENLDAYKEQEEKTARGPLQEHVFAECSRERILGLLAAMLPATKPGSPLSLSSLSPILPLLFRVVISNAGCLNETYHLTLGLLGQLLLRICPAEADAAVTEALTDKFELLNLGDGAALDVAGWKTTQLLFSLGAVCLDSRIGLDWACSVADILRNLNVSSQWCTVLASFTDHCILQLPQHLKRTNLFTLLVLVGFPEVLCMGTQAVFIDNANEQHNMILLKHFTEKNRAAVVDVKTRKRRTVKDYQLVQAHESSSRNDSESHEGQAVSPNSAHLSHYLKNFTSIVSFLLQTGVESSAQDAVEATWVLSLALKGLYNTLKKHGVDQAQEALQGSGLMQLLVRKCSKGTGFSKMWLLRDLEILSIMLYSSKREIHSMAEDADTETDGEKEREKEQDSDHSSCCADDADPNRPDPLEGLDEETKICFQITHDALNAPLHILRAMYELQMKRTDSFFLEVQKRFDGDAIKTDETIRTLAQKWQPSKRPRSDERSTKAVDTDIIIVPCVSKPTRCERATEETNVVTQKLITNTESDLQLSYAKQRRTKSSALLHKELDARSNKAVRQYLFKVNEAIAILYARHVLATLLADWPSDTPIREEDLELSGASHMAYILDMLMQLEERPMWEKILQKVLRGCSQSMLGNLSLTACQFMEEPGMAVQVRESKHPYDNNTNFEDKVHIPGAIFLSVKFDSRCHTEEGCDELLMASSSDFLQDLHTFSGSHQKWTDFEIPGDTLYFRFISDMSNTEWGYKFTVTGGHRGRFQTGFEILKQMLADEQALTHLPLPDIWEWQVGVACRQTGNQRLKAVHLLLRLLQCPSQWACDLTLLRPLWQLFTTMESGLCQDPTSITVLLPLHRALTELFFIAEAKAMEQNVLQEYLLALTTNEQLVVRTAQALKNIAAISLAINYPNKSTKQLNLSP", "length": 3038 }, "evidence": [ { "id": "A0A8V1AB20", "url": "https://omabrowser.org/oma/group/A0A8V1AB20/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "D3ZG78-1", "protein_name": "Zinc finger ZZ-type and EF-hand domain containing 1", "gene_name": "Zzef1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGNAPSNSSEDEAAAAGGEGWSPHQDWAADSGATPGPGPAAAVLPSAAALLEPARLREAAAALRPAPPCESLVSRHHGALLRWLEERLGRGEESVTLEQFRELLEARGAGCSGEQFEEAFAQFDAEGDGTVDAENMLEALKNSSGANLQGELSHVIRQLQACSLVPGFIDIFSESKEGLGTHSSMILRFLHRNRVSSMVIPYPMLDHCNNMCTMRSSVLKDSLDQLLQKEKESPGDLARSPEMDKLKSVTKCYAYIETSSNPADIYRMTNGETSSYWQSDGSARSHWIRLKMKPDVVLRHLSIAVAATDQSYMPQQVTVAVGRSASDLQEVRDVHIPSNVTGYVTLLENANISQLYVQINIKRCLSDGCDTRIHGLRAVGFQRVKKSGVSVSDASAIWYWSLLTSLVTASMETNPAFVQTVLHNTQKALQHMPPLSLSPGSTDFSTFLSPNVLEEVDSFLIRITSCCSTPEVELTLLAFALARGSIAKVMSSLCAISDHLDTQYDASSLISSMASVRQSLLLKYGKPLQLTLQACDVKGKEDKSGPENLLVEPWTRDGFLTETGKTRASTIFSAGTESAFQVTQIRIMVRRGGIGAQCGLVFAYNSPSDKFHAEEHFKRFEKYDRWKLQELRQFVKSRIGCSPDDLGEDDPIGWFELEEEWDEADVKLQQCRVAKFLMVKFLCTRQESAERLGVQGLSISGYLRPARAEAEQSILYAHCRRDTENIYGATLLLRTLQFIQQLAHDLVQQKESGLKYKSFLDFAGLDLQIFWNFYSKLKQNPREECICAQTLLLQLLQSCFSVLQGDPQAVSEEEKPAAQRPEGIQAAKELYTHLCDVVDRADGESMPMEILKQEVRNTLLNGAAIFFPDRQTRRNQLFTMMKNVTEHERKQSLQLTFRSLCTYFSDKDPGGLLLLPEKSDLATMNTSEVLAVMNTLLSVAARECELLMLGRAHGEVGSVLFSLFWSVQGSLLSWCFLQLKSTDAAAKELAMDLIEKYVGQFLASMRVILESLLSQYSGKTIVEKLCNSVFSMAARQLVIFLLDFCTLDVSHCTLLREFSTLTELLKKLCSDPEGGLSKLDVETWQQEQPVVLHTWTKESTHNYENNCHEVSVFVSPGATYFEVEFDERCETEKRYDYLEFTDSRGGKTRYDTKVGTYKWPKKVTFKDGPRLQFLFHSDSSNNEWGYKFTVTAYGLPDVAVSWGLDLQLLVSRLMGRLASQCMALKSVHQLGSNLAISQAKLTAVLNSPLWKPVFRHQICPELELEASWPTHPHQDGKEVKNIPDDPCRHFLLDFAQSEPAQNFCGPYSELFKGFIQACRKQAPKTDIVAGSTIDQAVNATFAALVYRTPDLYEKLQKYVHSGGKIALPEEFSQVYSLADGIRIWMLEMKQKSLVSMGNDSEEKRGLETAEVNPENLAKECIQKSLLLLKFLPMSKSSKENCDKLVPVDETDRLQPLDRRQRTSSVVEEHFQGSASPTEAATPAADDKSPGLEMQPKLLPSSGPSAAEVSTAEEPSSPSTPTRRPPFTRGRLRLLSFRSMEETRPVPTVKEKYPVLKDVMDFIKDQSLSHESIVKVLSLRKAQAQSILEVLRIIQYCTESLGQPHCFHPPYILFLLELLTCQKDFTNYFGHLEGCGADLHKEIRDTYYQLVLFLVKAIKGFSSINDRSLLPAVSCVQTALLHLLDMGWEPSDLAFFVDIQLPDLLMNMSQENISIHDSVISQWSEEDELADAKQNSEWMDECQDGMFEAWYEKIAQEDPEKQRKMHMFIARYCDLLNVDISCDGCDEIAPWHRYRCLQCSDMDLCKTCFLGGVKPEGHGDDHEMVNMEFTCDHCQGLIIGRRMNCNVCDDFDLCYGCYAAKKYSYGHLPTHSITAHPMVTIRISDRQRFIQPYIHNYSWLLFAALALYSAHLTSTEHVDGEQLDPQARGSAATLRSQCMQLVGDCLMKAHQGKGLKALALLGVLPDGDSTSENQALPVTVSIQASEEQLEKKTAQPAEGPADAGLFVPCNGKRATDKEVGPLDCKQKKKAGEDLSIMKDPSCQIQVSDPPASDHVPPGLPDAEHPDRSSQAPMEEKAITPSPEQVFAECSQKRILGLLAAMLPPIKSGPTVPLIDLEHVLPLMFQVVISNAGHLNETYHLTLGLLGQLIIRLQPAEVDAAVMKVLSAKHNLFATADNAVVPDGWKTTHLLFSLGAVCLDSRVGLDWACSMAEILRSLNNAPLWRDVIATFTDHCIKQLPFQLKHTNIFTLLVLVGFPQVLCVGTRCVYMDNANEPHNVIILKHFTEKNRAVIVDVKTRKRKTVKDYQLVQKGGGQECGTSQAQLSQYSQHFAFIASHLLQTSMDSHCPEAVEATWVLSLALKGLYKTLKTHGFEETHATFLHTDLLKLLVKKCSKGTGFSKTWLLRDLEILSIMLYSSKKEINTLTEHGDLELDERGDQEEELDRPVSSPGEAEQKKLDPLESLDEPTRICFLMAHDALNAPLHILRAIYELQMKKTDSFFLEVQKRFDGDELTTDERIRSLAQRWQPSRSLRLEEQSAKAVDTDMIILPCLSRPARSDQATSESNPVTQKLISSTESELQQSYAKQRRSKSAALLHKELNCKSKRAVRDYLFRVNEATAVLYARHVLASLLAEWPGHVPVSEDILELSGPAHMTYILDMFMQLEEKHQWEKILQKVLQGCRESMLGTMALAACQFMEEPGMEVQVRESKHPYNNNTSFEDKVHIPGAIYLSIKFDPQCNTEEGCDELAMSSSSDFQQDRHNFSGSQQKWKDFELPGDTLYYRFTSDMSNTEWGYRFTVTAGHLGRFQTGFEILKQMLSEERVVPHLPLGKIWEWLVGVACRQTGHQRLKAIHLLLRIVRCCSHSDLCDLGLLKPLWQLFTHMEYGLFEDVTQPGILLPLHRALTELFFVTENRAQELGLLQEYLLALTTEDHLLRCAAQALQNIAAISLAINYPNKATRLWNVEC", "length": 2965 }, "evidence": [ { "id": "A0A8V1AB20", "url": "https://omabrowser.org/oma/group/A0A8V1AB20/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O43149-1", "protein_name": "Zinc finger ZZ-type and EF-hand domain-containing protein 1", "gene_name": "ZZEF1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGNAPSHSSEDEAAAAGGEGWGPHQDWAAVSGTTPGPGVAAPALPPAAALLEPARLREAAAALLPTPPCESLVSRHRGALFRWLEERLGRGEESVTLEQFRELLEARGAGCSSEQFEEAFAQFDAEGDGTVDAENMLEALKNSSGANLQGELSHIIRQLQACSLVPGFTDIFSESKEGLDIHSSMILRFLHRNRLSSAVMPYPMLEHCNNMCTMRSSVLKESLDQLVQKEKESPGDLTRSPEMDKLKSVAKCYAYIETSSNSADIDKMTNGETSSYWQSDGSACSHWIRLKMKPDVVLRHLSIAVAATDQSYMPQQVTVAVGRNASDLQEVRDVHIPSNVTGYVTLLENANVSQLYVQINIKRCLSDGCDTRIHGLRAVGFQRVKKSGVSVSDASAIWYWSLLTSLVTASMETNPAFVQTVLHNTQKALRHMPPLSLSPGSTDFSTFLSPNVLEEVDSFLIRITSCCSTPEVELTLLAFALARGSVAKVMSSLCTITDHLDTQYDASSLILSMASVRQNLLLKYGKPLQLTLQACDVKGKEDKSGPENLLVEPWTRDGFLTETGKTRASTIFSTGTESAFQVTQIRIMVRRGGIGAQCGLVFAYNSSSDKFCAEEHFKRFEKYDKWKLQELRQFVKSRIGCSSDDLGEDDPIGWFELEEEWDEADVKLQQCRVAKYLMVKFLCTRQESAERLGVQGLTISGYLRPARAEAEQSVTCAHCRKDTEESVCGATLLLRTLQFIQQLAHDLVQQKESGLKYKSFLDFAGLDLQIFWNFYSKLKQNPREECVSAQTLLLQLLQSCFSVLQGDVLAASEEEKAPIQSPKGVEAAKELYTHLCDVVDKVDGDSVPMEILKQEVRNTLLNGAAIFFPNRQTRRNHLFTMMNVTEQEHKQSLQLTFRSLCTYFSDKDPGGLLLLPEKNDLAKMNISEVLAVMDTLVSVAARECELLMLSGAPGEVGSVLFSLFWSVQGSLLSWCYLQLKSTDSGAKDLAVDLIEKYVGQFLASMRAILESLFSQYSGKTIVERLCNSVFSMAARQLVIFLLDFCTLDIPHCVLLREFSVLTELLKKLCSGPEGGLRKLDVETWQQEQPVVLHTWTKESAHNYENNCHEVSVFVSPGATYFEVEFDDRCETEKRYDYLEFTDARGRKTRYDTKVGTDKWPKKVTFKAGPRLQFLFHSDSSHNEWGYKFTVTACGLPDVAVSWGLDLQLLVSRLMGRLASQCMALKSVRQLGSNMVVPQAKMALVLSSPLWKPVFRHQVCPELELEASWPTHPHRNSKEVKNIPDDPCRHFLLDFAQSEPAQNFCGPYSELFKGFIQACRKQAPKTDIVAGSTIDQAVNATFAALVYRTPDLYEKLQKYVNSGGKIALSEEFAQVYSLADGIRIWMLEMKQKSLMSLGNEAEEKHSSEATEVNPESLAKECIEKSLLLLKFLPTGISSKESCEKLETADETSHLQPLNKRQRTSSVVEEHFQASVSPTEAAPPATGDQSPGLGTQPKLPSSSGLPAADVSPATAEEPLSPSTPTRRPPFTRGRLRLLSFRSMEEARLVPTVKEKYPVLKDVMDFIKDQSLSHRSVVKVLSLRKAQAQSILEVLKITQHCAESLGQPHCFHPPFILFLLELLTCQKDFTNYFGHLEGCGADLHKEIRDTYYQLVLFLVKAVKGFSSLNDRSLLPALSCVQTALLHLLDMGWEPNDLAFFVDIQLPDLLMKMSQENISVHDSVISQWSEEDELADAKQNSEWMDECQDGMFEAWYEKIAQEDPEKQRKMHMFIARYCDLLNVDISCDGCDEIAPWHRYRCLQCSDMDLCKTCFLGGVKPEGHGDDHEMVNMEFTCDHCQGLIIGRRMNCNVCDDFDLCYGCYAAKKYSYGHLPTHSITAHPMVTIRISDRQRLIQPYIHNYSWLLFAALALYSAHLASAEDVDGEKLDPQTRSSATTLRSQCMQLVGDCLMKAHQGKGLKALALLGVLPDGDSSLEDQALPVTVPTGASEEQLEKKAVQGAELSEAGNGKRAVHEEIRPVDFKQRNKADKGVSLSKDPSCQTQISDSPADASPPTGLPDAEDSEVSSQKPIEEKAVTPSPEQVFAECSQKRILGLLAAMLPPLKSGPTVPLIDLEHVLPLMFQVVISNAGHLNETYHLTLGLLGQLIIRLLPAEVDAAVIKVLSAKHNLFAAGDSSIVPDGWKTTHLLFSLGAVCLDSRVGLDWACSMAEILRSLNSAPLWRDVIATFTDHCIKQLPFQLKHTNIFTLLVLVGFPQVLCVGTRCVYMDNANEPHNVIILKHFTEKNRAVIVDVKTRKRKTVKDYQLVQKGGGQECGDSRAQLSQYSQHFAFIASHLLQSSMDSHCPEAVEATWVLSLALKGLYKTLKAHGFEEIRATFLQTDLLKLLVKKCSKGTGFSKTWLLRDLEILSIMLYSSKKEINALAEHGDLELDERGDREEEVERPVSSPGDPEQKKLDPLEGLDEPTRICFLMAHDALNAPLHILRAIYELQMKKTDYFFLEVQKRFDGDELTTDERIRSLAQRWQPSKSLRLEEQSAKAVDTDMIILPCLSRPARCDQATAESNPVTQKLISSTESELQQSYAKQRRSKSAALLHKELNCKSKRAVRDYLFRVNEATAVLYARHVLASLLAEWPSHVPVSEDILELSGPAHMTYILDMFMQLEEKHEWEKILQKVLQGCREDMLGTMALAACQFMEEPGMEVQVRESKHPYNNNTNFEDKVHIPGAIYLSIKFDSQCNTEEGCDELAMSSSSDFQQDRHSFSGSQQKWKDFELPGDTLYYRFTSDMSNTEWGYRFTVTAGHLGRFQTGFEILKQMLSEERVVPHLPLAKIWEWLVGVACRQTGHQRLKAIHLLLRIVRCCGHSDLCDLALLKPLWQLFTHMEYGLFEDVTQPGILLPLHRALTELFFVTENRAQELGVLQDYLLALTTDDHLLRCAAQALQNIAAISLAINYPNKATRLWNVEC", "length": 2961 }, "evidence": [ { "id": "A0A8V1AB20", "url": "https://omabrowser.org/oma/group/A0A8V1AB20/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5SSH7-1", "protein_name": "Zinc finger ZZ-type and EF-hand domain-containing protein 1", "gene_name": "Zzef1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGNAPSNSSEDEAAAAGGEGWSPHQDWAADSGTTPGPGPAAAVLPSAAALLEPARLREAAAALRPAPPCESLVSRHHGALLRWLEERLGRGEESVTLEQFRELLEARGAGCSGEQFEEAFAQFDAEGDGTVDAENMLEALKNSSGANLQGELSHVIRQLQACSLVPGFIDIFSESKEGLGIHSSMILRFLHRNRISSMVIPYPMLDHCNNMCTMRSSVLKESLDQLVQKEKESPGDLARSPEMDKLKSVTKCYAYIETSSNPADIYRMTNGETSSYWQSDGSARSHWIRLKMKPDVVLRHLSIAVAATDQSYMPQQVTVAVGRSASDLQEVRDVHIPSNVTGYVTLLENANISQLYVQINIKRCLSDGCDTRIHGLRAVGFQRVKKSGVSVSDASAIWYWSLLTSLVTASMETNPAFVQTVLHNTQKALQHMPPLSLSPGSTDFSTFLSPNVLEEVDSFLIRITSCCSTPEVELTLLAFALARGSIAKVMSSLCTITDHLDTQYDASSLISSMASVRQNLLLKYGKPLQLTLQACDVKGKEDKSGPENLLVEPWTRDGFLTETGKTRASTIFSTGSDSAFQVTQIRIMVRRGGIGAQCGLVFAYNSPSNKFHAEEHFKRFEKYDKWKLQELRQFVKSRIGCSSDDLGEDDPIGWFELEEEWDEADVKLQQCRVAKFLMVKFLCTRQESAERLGVQGLSISGYLRPARAEAEQSILYAHCRRDTENIHGATLLLRTLQFIQQLSHDLMQQKESGLKHKSFLDFAGLDLQIFWKFYSKLKQNRREECICAQTLLLKLLQSCFSVLQGDPQAASEEEKPTAQRSEGIQAAKELYTHLCNVVDKPNGNSMPMEILKQEVRNTLLNGAAIFFPDRQTRRSQLFTMMKSVTEHERKQSLQLTFHSLCTYFSDKDPGGLLLLPEKSDLATMNTSEVLAVMNTLLSVAARECELLMLNRSHGAVGSVLFSLFWSVQGSLLSWCFLQLKSTDAAAKELAMDLIEKYVGQFLASMRVILESLLSQYSGKTIVEKLCNSVFSMAARQLVIFLLDFCTLDVSHCTLLREFSTLTELLKKLCSDPEGGLSKLDVETWQQEQPVVLHTWTKESTHNYENNCHEVSVFISPGATYFEVEFDERCETEKRYDYLEFTDSRGGKTRYDTKVGTYKWPKKVTFKDGPRLQFLFHSDSSNNEWGYKFTVTAYGLPDVAVSWGLDLQLLVSRLMGRLASQCMALKSVHQLGSNMAVSQAKLTSVLNSPLWKPVFRHQICPELELEASWPTHPHKDGKEVKNIPDDPCRHFLLDFAQSEPAQNFCGPYSELFKGFIQACRKQAPKTDIVAGSTIDQAVNATFAALVYRTPDLYEKLQKYVNSGGKIALTEEFSQVYSLADGIRIWMLEMKQKSLLSLGNDSEEKRGLEAAEVNPESLAKECIQKSLLLLKFLPMSKSSKENCDKLETVDETDHLQPLDRRQRTSSVVEEHFQGSASPTEAATPAAGDRSPALEIQPKLLPSSGPCVAEVSTAEEPSPPSTPTRRPPFTRGRLRLLSFRSMEETRPVPTVKEKYPVLKDVMDFIKDQSLSHESVVKVLSLRKAQGQSILEVLRIIQYCTESLGQPHCFHPPYILFLLELLTCQKDFTNYFGHLEGCGADLHREIRDTYYQLVLFLVKAIKRFSSINDRSLLPALSCVQTALLHLLDMGWEPSDLAFFVDIQLPDLLMNMSQENISVHDSVISQWSEEDELADAKQNSEWMDECQDGMFEAWYEKIAQEDPEKQRKMHMFIARYCDLLNVDISCDGCDEIAPWHRYRCLQCSDMDLCKTCFLGGVKPEGHGDDHEMVNMEFTCDHCQGLIIGRRMNCNVCDDFDLCYGCYTAKKYSYGHLPTHSITAHPMVTIRISDRQRLIQPYIHNYSWLLFAALALYSAHLTSTEQVDGEQLDPQARTNAATLRSQCMQLVGDCLMKAHQGKGLKALALLGVLPDGDSTSENQALPVTVSFQASEEQADAGLLVPCNGKRAADTEVRPLDYKQKKKAGEDLSIVKDPSCQTQVSDAPASAHVPPGLPDAEHPEVSAQVLVEEKAITPNPEQVFAECSQKRILGLLAAMLPPIKSGPTVPLIDLEHVLPLMFQVVISNAGHLNETYHLTLGLLGQLIIRLQPAEVDAAVMKVLSAKHNLRVGLDWACSMAEILRSLNNAPLWRDVIATFTDHCIKQLPFQLKHTNIFTLLVLVGFPQVLCVGTRCVYMDNANEPHNVIILKHFTEKNRAVIVDVKTRKRKTVKDYQLVQKGGGQECGTSQSQLSQYSQHFAFIASHLLQTSMDSHCPEAVEATWVLSLALKGLYKTLKAHGFEETHATFLQTDLLKLLVKKCSKGTGFSKTWLLRDLEILSIMLYSSKKEINTLAEHGDLELDERGDQEEELDRPVSSPGEAEQKKLDPLENLDEPTRICFLMAHDALNAPLHILRAIYELQMKKTDSFFLEVQKRFDGDELTTDERIRSLAQRWQPSRSLRLEEQSAKAVDTDMIILPCLSRPARSDQATPESNPVTQKLISSTESELQQSYAKQRRSKSAALLHKELNCKSKRAIRDYLFRVNEATSVLYARHVLASLLAEWPGHVPVSEDILELSGPAHMTYILDMFMQLEEKHQWEKILQKVLQGCRENMLGTMALAACQFMEEPGMEVQVRESKHSYNNNTSFEDKVHIPGAIYLSIKFDPQRNTEEGCDELAMSSSSDFQQDRHNFSGSQQKWKDFELPGDTLYYRFTSDMSNTEWGYRFTVTAGHLGRFQTGFEILKQMLSEERVVPHLALGKIWEWLVGVACRQTGHQRLKAIHLLLRIVQCCSHSDLCDLGLLKPLWQLFTHMEYGLFEDVTQPGILLPLHRALTELFFVTENRAQELGLLQEYLLALTTEDHLLRCAAQALQNIAAISLAINYPNKATRLWNVEC", "length": 2924 }, "evidence": [ { "id": "A0A8V1AB20", "url": "https://omabrowser.org/oma/group/A0A8V1AB20/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AB20", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB20" } ], "pmid": "" }, { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AB20", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB20" } ], "pmid": "" }, { "name": "histone binding", "id": "GO:0042393", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042393", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AB20", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB20" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1332, "end_pos": 1334, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1392, "end_pos": 1394, "annotation": "n_glycosylation_sequon" }, { "start_pos": 139, "end_pos": 141, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1723, "end_pos": 1725, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1907, "end_pos": 1909, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1984, "end_pos": 1986, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2069, "end_pos": 2071, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2148, "end_pos": 2150, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2231, "end_pos": 2233, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2693, "end_pos": 2695, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2726, "end_pos": 2728, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2966, "end_pos": 2968, "annotation": "n_glycosylation_sequon" }, { "start_pos": 321, "end_pos": 323, "annotation": "n_glycosylation_sequon" }, { "start_pos": 336, "end_pos": 338, "annotation": "n_glycosylation_sequon" }, { "start_pos": 348, "end_pos": 350, "annotation": "n_glycosylation_sequon" }, { "start_pos": 634, "end_pos": 636, "annotation": "n_glycosylation_sequon" }, { "start_pos": 805, "end_pos": 807, "annotation": "n_glycosylation_sequon" }, { "start_pos": 881, "end_pos": 883, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AB20", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB20" }, { "id": "PS51284", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51284" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DOC", "eco_id": "ECO_0000259", "start_pos": 223, "end_pos": 402, "start_aa": "Leu", "end_aa": "Ser", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1AB20", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB20" }, { "id": "PS50222", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50222" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EF-hand", "eco_id": "ECO_0000259", "start_pos": 108, "end_pos": 143, "start_aa": "Gly", "end_aa": "Ala", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1AB20", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB20" }, { "id": "PS50135", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50135" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "ZZ-type", "eco_id": "ECO_0000259", "start_pos": 1788, "end_pos": 1843, "start_aa": "Asn", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1332, "end_pos": 1334 }, { "start_pos": 1392, "end_pos": 1394 }, { "start_pos": 139, "end_pos": 141 }, { "start_pos": 1723, "end_pos": 1725 }, { "start_pos": 1907, "end_pos": 1909 }, { "start_pos": 1984, "end_pos": 1986 }, { "start_pos": 2069, "end_pos": 2071 }, { "start_pos": 2148, "end_pos": 2150 }, { "start_pos": 2231, "end_pos": 2233 }, { "start_pos": 2693, "end_pos": 2695 }, { "start_pos": 2726, "end_pos": 2728 }, { "start_pos": 2966, "end_pos": 2968 }, { "start_pos": 321, "end_pos": 323 }, { "start_pos": 336, "end_pos": 338 }, { "start_pos": 348, "end_pos": 350 }, { "start_pos": 634, "end_pos": 636 }, { "start_pos": 805, "end_pos": 807 }, { "start_pos": 881, "end_pos": 883 } ] }, "class_list": [], "section_stats": [ { 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gallus [9031]" } ], "gene": [ { "name": "DCXR", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB26", "locus": { "chromosome": "18", "start_pos": 5613361, "end_pos": 5609322, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029170", "url": "https://www.ensembl.org/id/ENSGALG00010029170" } ] } } ], "crossref": [ { "id": "A0A8V1AB26", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AB26", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd05351", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05351", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "374066", "url": "https://www.ncbi.nlm.nih.gov/gene/374066", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002347", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002347", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020904", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020904", "database": 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"http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44252", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR44252:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44252:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13561", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13561", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1AB26", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB26", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AB26-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB26-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AIG3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIG3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AIG3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIG3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MWSCWSGVQRAIEMIRGLEHLSYKERPRIGRAVAVALCKAGARVTALSRTAADLESLVRECPGIEPLCLDLADWDATEAAVGAAGPFELLVNNAAVAMLQPFLQVTREAVKRSFDVNFRAVLHVSQIVARQMIAQGLPGAIVNVSSQASQRALRDHAVYCSTKSALDMLSKVMAMELGPHKIRVNTVNPTVVMTDMGRINWSDPQKSAAMINRIPLGKFAEVDDVVNSILFLLSDKSAMTTGSSLMVDGGFLVS", "length": 254, "header": "tr|A0A8V1AB26-1|A0A8V1AB26_CHICK Isoform 1 of Dicarbonyl and L-xylulose reductase OS=Gallus gallus OX=9031 GN=DCXR PE=3 SV=1 CANONICAL=A0A8V1AB26-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AB26-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB26/entry#A0A8V1AB26-1", "sequence": { "sequence": "MWSCWSGVQRAIEMIRGLEHLSYKERPRIGRAVAVALCKAGARVTALSRTAADLESLVRECPGIEPLCLDLADWDATEAAVGAAGPFELLVNNAAVAMLQPFLQVTREAVKRSFDVNFRAVLHVSQIVARQMIAQGLPGAIVNVSSQASQRALRDHAVYCSTKSALDMLSKVMAMELGPHKIRVNTVNPTVVMTDMGRINWSDPQKSAAMINRIPLGKFAEVDDVVNSILFLLSDKSAMTTGSSLMVDGGFLVS", "length": 254, "header": "tr|A0A8V1AB26-1|A0A8V1AB26_CHICK Isoform 1 of Dicarbonyl and L-xylulose reductase OS=Gallus gallus OX=9031 GN=DCXR PE=3 SV=1 CANONICAL=A0A8V1AB26-1" }, "locus": { "chromosome": "18", "start_pos": 5613123, "end_pos": 5609521, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070489.1", "url": "https://www.ensembl.org/id/ENSGALT00010070489.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043180.1", "url": "https://www.ensembl.org/id/ENSGALP00010043180.1" } ] } }, { "isoform_ac": "A0A8V1AIG3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB26/entry#A0A8V1AIG3-1", "sequence": { "sequence": "MEPDLSFRGRRALVTGAGKGIGRAVAVALCKAGARVTALSRTAADLESLVRECPGIEPLCLDLADWDATEAAVGAAGPFELLVNNAAVAMLQPFLQVTREAVKRSFDVNFRAVLHVSQIVARQMIAQGLPGAIVNVSSQASQRALRDHAVYCSTKSALDMLSKVMAMELGPHKIRVNTVNPTVVMTDMGRINWSDPQKSAAMINRIPLGKFAEVDDVVNSILFLLSDKSAMTTGSSLMVDGGFLVS", "length": 246, "header": "tr|A0A8V1AIG3-1|A0A8V1AB26_CHICK Computationally mapped isoform of Dicarbonyl and L-xylulose reductase OS=Gallus gallus OX=9031 GN=DCXR PE=3 SV=1 CANONICAL=A0A8V1AB26-1" }, "locus": { "chromosome": "18", "start_pos": 5613123, "end_pos": 5610306, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070488.1", "url": "https://www.ensembl.org/id/ENSGALT00010070488.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043179.1", "url": "https://www.ensembl.org/id/ENSGALP00010043179.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:374066", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:374066", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A286ZQ44-1", "protein_name": "L-xylulose reductase", "gene_name": "DCXR", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MELGLAGRRALVTGAGKGIGRSTVQALHAAGAQVVAVSRTQADLDSLVRECPGVEPVCVDLGDWEATERALGGVGPVDLLVNNAAVALMQPFLEVTKEACDRSFEVNLRAVIQVSQIVARGLIARGAPGSIVNVSSQASQRALPNHSVYCSTKGALDMLTKMMALELGPHKIRVNAVNPTVVMTPMGRANWSNPPKAKAMLDRIPLGRFAEVEHVVDAILFLLSDRSSMTTGSTLPVDGGYLAT", "length": 244 }, "evidence": [ { "id": "A0A8V1AB26", "url": "https://omabrowser.org/oma/group/A0A8V1AB26/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3GXD0-1", "protein_name": "L-xylulose reductase", "gene_name": "Dcxr", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDLGLAGRRALVTGAGKGIGRSTVLALQAAGARVVAVSRTQADLDSLASECPGVETVCVDLADWETTEKALSSVGPVDLLVNNAAVALLQPFLEVTKEACDTSFNVNLRAVIQVSQIVARGMIARGVPGAIVNVSSQASQRALTNHSVYCSTKGALDMLTKMMALELGPHKIRVNAVNPTVVMTPMGRTNWGDPHKAKVMLDRIPLGKFAEVENVVDAILFLLSNRSSLTTGCTLPVDGGFLAT", "length": 244 }, "evidence": [ { "id": "A0A8V1AB26", "url": "https://omabrowser.org/oma/group/A0A8V1AB26/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q7Z4W1-1", "protein_name": "L-xylulose reductase", "gene_name": "DCXR", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MELFLAGRRVLVTGAGKGIGRGTVQALHATGARVVAVSRTQADLDSLVRECPGIEPVCVDLGDWEATERALGSVGPVDLLVNNAAVALLQPFLEVTKEAFDRSFEVNLRAVIQVSQIVARGLIARGVPGAIVNVSSQCSQRAVTNHSVYCSTKGALDMLTKVMALELGPHKIRVNAVNPTVVMTSMGQATWSDPHKAKTMLNRIPLGKFAEVEHVVNAILFLLSDRSGMTTGSTLPVEGGFWAC", "length": 244 }, "evidence": [ { "id": "A0A8V1AB26", "url": "https://omabrowser.org/oma/group/A0A8V1AB26/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q91X52-1", "protein_name": "L-xylulose reductase", "gene_name": "Dcxr", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDLGLAGRRALVTGAGKGIGRSTVLALKAAGAQVVAVSRTREDLDDLVRECPGVEPVCVDLADWEATEQALSNVGPVDLLVNNAAVALLQPFLEVTKEACDTSFNVNLRAVIQVSQIVAKGMIARGVPGAIVNVSSQASQRALTNHTVYCSTKGALDMLTKMMALELGPHKIRVNAVNPTVVMTPMGRTNWSDPHKAKAMLDRIPLGKFAEVENVVDTILFLLSNRSGMTTGSTLPVDGGFLAT", "length": 244 }, "evidence": [ { "id": "A0A8V1AB26", "url": "https://omabrowser.org/oma/group/A0A8V1AB26/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "xylulose metabolic process", "id": "GO:0005997", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005997", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AB26", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB26" } ], "pmid": "" }, { "name": "glucose metabolic process", "id": "GO:0006006", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006006", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AB26", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB26" } ], "pmid": "" }, { "name": "positive regulation of reactive oxygen species metabolic process", "id": "GO:2000379", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000379", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AB26", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB26" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "L-xylulose reductase (NADPH) activity", "id": "GO:0050038", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050038", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AB26", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB26" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AB26", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB26" } ], "pmid": "" }, { "name": "oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor", "id": "GO:0016655", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016655", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AB26", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB26" } ], "pmid": "" }, { "name": "carbonyl reductase (NADPH) activity", "id": "GO:0004090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004090", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AB26", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB26" } ], "pmid": "" }, { "name": "oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor", "id": "GO:0016616", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016616", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AB26", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB26" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasmic microtubule", "id": "GO:0005881", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005881", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AB26", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB26" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 143, "end_pos": 145, "annotation": "n_glycosylation_sequon" }, { "start_pos": 200, "end_pos": 202, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 143, "end_pos": 145 }, { "start_pos": 200, "end_pos": 202 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": 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"sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AB28-1", "uniprot_ac": "A0A8V1AB28", "uniprot_id": "A0A8V1AB28_CHICK", "mass": { "chemical_mass": 126091.0, "monoisotopic_mass": 126091.0 }, "refseq": { "ac": "XP_001232162", "name": "double-stranded RNA-specific adenosine deaminase", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001232162" }, "gene_names": [ { "name": "ADAR", "type": "recommended", "evidence": [ { "id": "A0A8V1AB28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB28" } ] }, { "name": "ADAR", "type": "synonym", "evidence": [ { "id": "XP_001232162", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001232162" } ] } ], "protein_names": [ { "name": "Adenosine deaminase RNA specific", "type": "synonym", "evidence": [ { "id": "A0A8V1AB28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB28/entry#names_and_taxonomy" } ] }, { "name": "double-stranded RNA-specific adenosine deaminase", "type": "synonym", "evidence": [ { "id": "XP_001232162", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001232162" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052556.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_001232162.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_001232162", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001232162" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AB28", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB28" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ADAR", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB28", "locus": { "chromosome": "25", "start_pos": 1963940, "end_pos": 1975536, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027916", "url": "https://www.ensembl.org/id/ENSGALG00010027916" } ] } } ], "crossref": [ { "id": "A0A8V1AB28", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AB28", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd19913", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19913", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd19914", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19914", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd19915", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19915", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "769675", "url": "https://www.ncbi.nlm.nih.gov/gene/769675", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002466", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002466", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014720", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014720", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036388", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036388", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036390", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036390", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042371", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042371", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044456", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044456", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044457", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044457", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:769675", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:769675", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ERMQMKR", "url": "https://omabrowser.org/oma/group/ERMQMKR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AB28", "url": "https://www.orthodb.org/?gene=A0A8V1AB28", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10910", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10910", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10910:SF107", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10910:SF107", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00035", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00035", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02137", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02137", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02295", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02295", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-75102", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-75102", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-77042", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-77042", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9833482", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9833482", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_001232162", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001232162", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AB28", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB28", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AB28-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB28-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSRGTAQGKGSHLTRARHHCSNAPPAFFNGPHPSQKANWDSSWHLAEQDGDVCLIHRPQSYSKLCAGGWQAAAPAGRGQGGRGKAGWHRFSSKQQQVEAPPHRPPPRYRSQEDLQRDSFAIRLNLQRLSLAGQSLEQEILSILGQLQVGETRTVHDLARKLKTQRKEVNRVLYKLLKEGKLHRIVGTPPLWRIANPNGEGEGSHPEYGVGSADPGPESREERSTAAVRDPNPTMAETKDKICNFLFSVADTTAINLARNIGFSRAKDVNSFLSALEKLGDVRKQNCTPPRWSLTSRKRERMEMRLKATAAPADPAAEPGVLPSAPAALQEVAAASPAATAAEQSVGDGQQPSEQSVRSVAAGREAAVPEESKPLFSGFSSYDSSENSRWASDDIPDYLNTITKQDGSESIMHTQSSPSYTAQFNTIFPCTPVEKLLACQEKNPVSGLTEYSQFTYQHCEFTMLEQSGPSHEPRFKFQAVINGRPFPPAEAGSKKLAKQEAAANAMRILMQEAEDGSPDGPHTDMPFVSDSSELEQPLHSEPELSPAAAQLSLLSGKHPISVLMEYGQKSGNMIEFLLLSQDGPPHDPRFSYCVKMGDQIFPAVVGNSKKGAKQMAAEVAVKILSGESAPRVPPEQPVVKPQGERSCALQIVIPDEPKAVKSKGVGELIKYLNVNPVSGLLEYARSNGFAAEFKLIDQTGPPHDPKFVYQAKVGGRWFPAVTAHSKKQGKQEAADAALRVLIGETEKAERMGGMSVAELPVRGSTLHDQMAMLSHQRFNVLTACIQHSLLGRKILAAIIMRKGSQDLGVVVSIGTGNRCVKGEELSLKGETVNDCHAEIISRRGFVRFLYSELMKYDPCKPSAEESIFEPAGGRRLKIKSSITFHLYISTAPCGDGALFDKSCSDQASVVGPAEHQPLFENSKQGKLRTKVENGEGTIPVESSDIVPTWDGIQHGERLRTMSCSDKILRWNVLGLQGALLSHFIEPVYLSSVTLGYLYSQGHLTRAICCRLVRDGDVLQKRLQAPYQINHPEVGRVSVYDSARQTGKTKESSVNWCLADGSKVEVLDGTKGKVDGPKLEVSRVSKRKTFALFQQLCAKSDCKELQKLSVYSEAKKAAVQYQKAKQCFFNALEEMGYGSWICKPQEEDNFSIPDA", "length": 1153, "header": "tr|A0A8V1AB28-1|A0A8V1AB28_CHICK Isoform 1 of Adenosine deaminase RNA specific OS=Gallus gallus OX=9031 GN=ADAR PE=1 SV=1 CANONICAL=A0A8V1AB28-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AB28-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB28/entry#A0A8V1AB28-1", "sequence": { "sequence": "MSRGTAQGKGSHLTRARHHCSNAPPAFFNGPHPSQKANWDSSWHLAEQDGDVCLIHRPQSYSKLCAGGWQAAAPAGRGQGGRGKAGWHRFSSKQQQVEAPPHRPPPRYRSQEDLQRDSFAIRLNLQRLSLAGQSLEQEILSILGQLQVGETRTVHDLARKLKTQRKEVNRVLYKLLKEGKLHRIVGTPPLWRIANPNGEGEGSHPEYGVGSADPGPESREERSTAAVRDPNPTMAETKDKICNFLFSVADTTAINLARNIGFSRAKDVNSFLSALEKLGDVRKQNCTPPRWSLTSRKRERMEMRLKATAAPADPAAEPGVLPSAPAALQEVAAASPAATAAEQSVGDGQQPSEQSVRSVAAGREAAVPEESKPLFSGFSSYDSSENSRWASDDIPDYLNTITKQDGSESIMHTQSSPSYTAQFNTIFPCTPVEKLLACQEKNPVSGLTEYSQFTYQHCEFTMLEQSGPSHEPRFKFQAVINGRPFPPAEAGSKKLAKQEAAANAMRILMQEAEDGSPDGPHTDMPFVSDSSELEQPLHSEPELSPAAAQLSLLSGKHPISVLMEYGQKSGNMIEFLLLSQDGPPHDPRFSYCVKMGDQIFPAVVGNSKKGAKQMAAEVAVKILSGESAPRVPPEQPVVKPQGERSCALQIVIPDEPKAVKSKGVGELIKYLNVNPVSGLLEYARSNGFAAEFKLIDQTGPPHDPKFVYQAKVGGRWFPAVTAHSKKQGKQEAADAALRVLIGETEKAERMGGMSVAELPVRGSTLHDQMAMLSHQRFNVLTACIQHSLLGRKILAAIIMRKGSQDLGVVVSIGTGNRCVKGEELSLKGETVNDCHAEIISRRGFVRFLYSELMKYDPCKPSAEESIFEPAGGRRLKIKSSITFHLYISTAPCGDGALFDKSCSDQASVVGPAEHQPLFENSKQGKLRTKVENGEGTIPVESSDIVPTWDGIQHGERLRTMSCSDKILRWNVLGLQGALLSHFIEPVYLSSVTLGYLYSQGHLTRAICCRLVRDGDVLQKRLQAPYQINHPEVGRVSVYDSARQTGKTKESSVNWCLADGSKVEVLDGTKGKVDGPKLEVSRVSKRKTFALFQQLCAKSDCKELQKLSVYSEAKKAAVQYQKAKQCFFNALEEMGYGSWICKPQEEDNFSIPDA", "length": 1153, "header": "tr|A0A8V1AB28-1|A0A8V1AB28_CHICK Isoform 1 of Adenosine deaminase RNA specific OS=Gallus gallus OX=9031 GN=ADAR PE=1 SV=1 CANONICAL=A0A8V1AB28-1" }, "locus": { "chromosome": "25", "start_pos": 1974142, "end_pos": 1964430, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067668.1", "url": "https://www.ensembl.org/id/ENSGALT00010067668.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041411.1", "url": "https://www.ensembl.org/id/ENSGALP00010041411.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:769675", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:769675", "resource": "KEGG Pathway" }, { "id": "R-GGA-75102", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-75102", "resource": "Reactome", "description": "C6 deamination of adenosine" }, { "id": "R-GGA-77042", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-77042", "resource": "Reactome", "description": "Formation of editosomes by ADAR proteins" }, { "id": "R-GGA-9833482", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9833482", "resource": "Reactome", "description": "PKR-mediated signaling" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8M1P8J0-1", "protein_name": "3.5.4.37", "gene_name": "adar", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSRGRGGNYKDSQRFSLPFRKGQPQFYSSTTTGQSRGPRVPSPSSLSGSSPHPSFYSSYSSGPGVPPRDHPFPPRHSDPSLWASPQHGSDQISDSNGVSFRQNQVQFLRGQSAQAPQFKAPQPRGSQSSSRGEEVSTEPIQYQTGYRDFKSNSYSFGRRNCYGRGQDNWQGEQNFGPKKRSGWNHPHQKGQYYSNQHYKQFWNARANDLSSGIYNLSFGDRVKRVDTSDTLSCSNSSSKVSSSSSSFRDSLYLTPEIHQQVCAFLTSLRPAETIQAKVLGKKLGLPKKIVNKVLYDLLKSNQVVKQGETPPLWRLCEESRESIREKDQTQSSKDLEKEPGQSPYINQKVGGDFTTTSTPSPSKIPIDADSDTSDESEDSEGDDSCEKLLADQDKKTLSPTVQSVTLSTMADSKDSKEKILQYLYEAGTGNALVIAKNLGLRSAKQVNPTLYALEKQGDVNRNTEVNPPTWELSAHRQEKMDRQRKAAATANQDVNSAATLSLEDDEIANVALVNFEPMEGGGKPLVEMLDNDNVFGNTEIDIPGLEPVSKASDLSSSTHRNFQPNQFPYYQETPSNGGEQSQWASDDIPEFLNTIRSEVAVSLAAPPPPTQSMESNRLQKLKEARSKNPVSGLMEFAQHLGYTCEFLLLEQSGPSHDPRFRMQVMLDGRRFPAAEGSNKKVAKKDAAAITLKILWKELDGGGGEEEEEPNIEGAGSTTDMADDMGGTDTPPQALSRSLPGGKNPVSVLMEHSQRSGHPIQFIKTGQEGPSHDPRFMFRVKVGERLFQEASAPSKKAARQLAAEEAVKELMGDGLLHLNKPPSSFCPMGDSESQPMFPACPSLPPLTAAELQAAHEAGVGDLINHLNNNAVSGLLEYARARGFAAEIRLVGQSGPSHEPKFTYQAKLGGRWFPAVCASNKKQGKQEAADAALRVLIGEAEKAARTGELMPELPVSGSTIHDQIAMLSHQRFNALTARIQHSLLGRKILATIVMRNGTDSLGKVVSLGTGNRCVKGEELSLRGDTVNDCHAEIISRRGFIRFLYSELMKHWESPGDETIFELAGDGKLKIKSDITFHLYISTAPCGDGALFDKSCSEAAELNGSGHMPLFENIKQGKLRTKVENGEGTIPVESSDIVPTWDGIQHGERLRTMSCSDKILRWNVLGLQGALLTHFIHPIYLHSITLGYLYSHGHLTRAVCCRLSRDGDTFKSSLPANFTLNHPEVGRVSVYDSTRHTSKTKESSVNWSQPDQYSVEVLDGTKGKLDSPKMEVSRVSKSNLFRLFHALCQRAGRADLLALQSYAHAKMAATSFQEAKRLFFLALSQHGYGAWIGKPLEEKSFEGEAKSFEPMGGSGDVQASGCVVDPNSFLSSENNNFLSAAQGF", "length": 1381 }, "evidence": [ { "id": "A0A8V1AB28", "url": "https://omabrowser.org/oma/group/A0A8V1AB28/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "G3HBY8-1", "protein_name": "Double-stranded RNA-specific adenosine deaminase", "gene_name": "Adar", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAQGLRGPAGVFPHQARSYLDPNYEHSKWRHPQPHGPESYPGSFQLQQIDFLKGRLPEAPLIGQQSQSLPPSLPGHWPRFPGQPAQGKQLEIWGFPRSVALRTQGFHTGLPLPLPPSSRSLPWRGADRLCSHFRELSISQNPQQKILGRLEELGEGKATSAQVLARELRVPKKEINRILYSLERKGKLHRRGGSPPLWSLAPPHQAWTQPSRAVNPDTCGQTVPQEEPGLDSEDRDPASDLEGLPEPLDMAEIKEKICDYLFNVSNSSALNLAKNVGLTKARDVNAVLIDLERQGDVYRQGATPPIWCLTDKKRERLQIKRSTHGVPAAVPEATRSTSFPICHSPPSGASSSLATPKKVENGQEPVIKYESRYEARPGPVRLRAHAYHNGPSRAGYADSENGQWATDDIPDNLNSIHTAPGEFRAIMEMPSFYSPTLPRCSPYKKLTECQLKNPVSGLLEYAQFTSQTCDFNLIEQSGPSHEPRFKFQVVINGREFPPAEAGSKKVAKQDAAMKAMAILLREAKAKDSGNPEELSNCPMDEDSEKPAESQTSSSSATLFSGKSPVTTLLECMHKLGNSCEFRLLSKEGPAHDPKFQYCVAVGAQTFPTVSAPSKKVAKQMAAEEAMKALQEEAANSADDQSGGVNTESLDESVAPNKIRRIGELVRYLNTNPVGGLLEYARSHGFAAEFKLIDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQDAADAALRVLIGESEKAEQLGFAEVTPVTGASLRRTMLLLSRSPDAHPKTLPLSGSTFHDQIAMLSHRCFNALTNSFQPSLLGRKILAAIIMKRDPEDMGVVVSLGTGNRCVKGDSLSLKGETVNDCHAEIISRRGFIRFLYSELMKYNQHTAKNSIFELARGGEKLQIKKTVSFHLYISTAPCGDGALFDKSCSDRAVESTESRHYPVFENPKQGKLRTKVENGEGTIPVESSDIVPTWDGIRLGERLRTMSCSDKILRWNVLGLQGALLTHFLQPVYLKSVTLGYLFSQGHLTRAICCRVTRDGNAFEDGLRYPFIVNHPKVGRVSVYDSKRQSGKTKETSVNWCLADGYDLEILDGTRGTVDGPGKELSRVSKKNIFLQFKKLCSFRARRDLLQLSYGEAKKAARDYELAKNYFKKSLRDMGYGNWISKPQEEKNFYLCPVPND", "length": 1174 }, "evidence": [ { "id": "A0A8V1AB28", "url": "https://omabrowser.org/oma/group/A0A8V1AB28/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P55265-1", "protein_name": "Double-stranded RNA-specific adenosine deaminase", "gene_name": "ADAR", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNPRQGYSLSGYYTHPFQGYEHRQLRYQQPGPGSSPSSFLLKQIEFLKGQLPEAPVIGKQTPSLPPSLPGLRPRFPVLLASSTRGRQVDIRGVPRGVHLRSQGLQRGFQHPSPRGRSLPQRGVDCLSSHFQELSIYQDQEQRILKFLEELGEGKATTAHDLSGKLGTPKKEINRVLYSLAKKGKLQKEAGTPPLWKIAVSTQAWNQHSGVVRPDGHSQGAPNSDPSLEPEDRNSTSVSEDLLEPFIAVSAQAWNQHSGVVRPDSHSQGSPNSDPGLEPEDSNSTSALEDPLEFLDMAEIKEKICDYLFNVSDSSALNLAKNIGLTKARDINAVLIDMERQGDVYRQGTTPPIWHLTDKKRERMQIKRNTNSVPETAPAAIPETKRNAEFLTCNIPTSNASNNMVTTEKVENGQEPVIKLENRQEARPEPARLKPPVHYNGPSKAGYVDFENGQWATDDIPDDLNSIRAAPGEFRAIMEMPSFYSHGLPRCSPYKKLTECQLKNPISGLLEYAQFASQTCEFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDAAMKAMTILLEEAKAKDSGKSEESSHYSTEKESEKTAESQTPTPSATSFFSGKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSVSAPSKKVAKQMAAEEAMKALHGEATNSMASDNQPEGMISESLDNLESMMPNKVRKIGELVRYLNTNPVGGLLEYARSHGFAAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLIGENEKAERMGFTEVTPVTGASLRRTMLLLSRSPEAQPKTLPLTGSTFHDQIAMLSHRCFNTLTNSFQPSLLGRKILAAIIMKKDSEDMGVVVSLGTGNRCVKGDSLSLKGETVNDCHAEIISRRGFIRFLYSELMKYNSQTAKDSIFEPAKGGEKLQIKKTVSFHLYISTAPCGDGALFDKSCSDRAMESTESRHYPVFENPKQGKLRTKVENGEGTIPVESSDIVPTWDGIRLGERLRTMSCSDKILRWNVLGLQGALLTHFLQPIYLKSVTLGYLFSQGHLTRAICCRVTRDGSAFEDGLRHPFIVNHPKVGRVSIYDSKRQSGKTKETSVNWCLADGYDLEILDGTRGTVDGPRNELSRVSKKNIFLLFKKLCSFRYRRDLLRLSYGEAKKAARDYETAKNYFKKGLKDMGYGNWISKPQEEKNFYLCPV", "length": 1226 }, "evidence": [ { "id": "A0A8V1AB28", "url": "https://omabrowser.org/oma/group/A0A8V1AB28/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P55266-1", "protein_name": "Double-stranded RNA-specific adenosine deaminase", "gene_name": "Adar", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSQGFRGPTGVFPHQTQPCLDPSYEHSKWRYLQPRGSESYLRSFQLQQIEFLKGRLPEAPLIGAQTQSLPPFLPGHWPRFPGPPAQGKQPEIWGFPRSVTLRNQGFHIGPPLPPPHSRGPPWRGAEGLCSHFQELSISQNPEQKVLNRLEELGEGKATTAYALARELRTPKKDINRILYSLERKGKLHRGVGKPPLWSLVPLSQACTQPPRAVNSDKEVPRGEPDLDSEDGDPASDLEGPSELLDMAEIKEKICDYLFNVSKSSALNLAKNIGLAKARDVNAVLIDLERQGDVYREGATPPIWYLTDKKRERLQMKRSTHSGPAATPAAVSEATQSTSFPTCHPPQSGGSSSMATSKRVENGQEPVTKYESRHEARPGPVRLRPHAYHNGPSRAGYVASENGPWATDDIPDNLNSIHTAPGEFRAIMEMPSFYSPTLPRCSPYKKLTECQLKNPVSGLLEYAQFTSQTCDFNLIEQSGPSHEPRFKFQVVINGREFPPAEAGSKKVAKQDAAVKAMAILLREAKAKDSGQPEELSNCPMEEDPEKPAESQPPSSSATSLFSGKSPVTTLLECMHKLGNSCEFRLLSKEGPAHDPKFQYCVAVGAQTFPSVSAPSKKVAKQMAAEEAMKALQEEAANSADDQSGGANTDSLDESVAPNKIRRIGELVRYLNTNPVGGLLEYARSHGFAAEFKLIDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQDAADAALRVLIGESEKAEQLGFAEVTPVTGASLRRTMLLLSRSPDAHPKTLPLTGSTFHDQIAMLSHRCFNALTNSFQPSLLGRKILAAIIMKRDPEDMGVVVSLGTGNRCVKGDSLSLKGETVNDCHAEIISRRGFIRFLYSELMKYNHHTAKNSIFELARGGEKLQIKKTVSFHLYISTAPCGDGAHFDKSCSDRAVESTESRHYPVFENPKQGKLRTKVENGEGTIPVESSDIVPTWDGIRLGERLRTMSCSDKILRWNVLGLQGALLTHFLQPVYLKSVTLGYLFSQGHLTRAICCRVTRDGNAFEDGLRYPFIVNHPKVGRVSVYDSKRQSGKTKETSVNWCLADGYDLEILDGTRGTVDGPGKELSRVSKKNIFLQFKKLCSFRARRDLLQLSYGEAKKAARDYDLAKNYFKKSLRDMGYGNWISKPQEEKNFYLCPVPND", "length": 1175 }, "evidence": [ { "id": "A0A8V1AB28", "url": "https://omabrowser.org/oma/group/A0A8V1AB28/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q99MU3-1", "protein_name": "Double-stranded RNA-specific adenosine deaminase", "gene_name": "Adar", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSQGFRGPTGVFPHQTQSYLDPSHEHSKWRYPQPQGPESYPRSFQLQQIEFLKGRLPEAPLIGIQTQSLPPFLPGHWPRFPGPPAQDRQLEIWEFPRSVTLRNQGFHIGPPLPPPHSRGTPWRGADGLCSHFRELSISQSPEQKVLNRLEELGEGKATTAHVLARELRIPKRDINRILYSLEKKGKLHRGRGKPPLWSLVPLSQAWTQPPGVVNPDSCIQEFPRGEPGLDSEDGDPASDLEGPSEPLDMAEIKEKICDYLFNVSNSSALNLAKNIGLTKARDVTSVLIDLERQGDVYRQGATPPIWYLTDKKRERLQMKRSTHSAPAPTPTAVPEATRSPSFPACHPPPAGASSSVAASKRVENGQEPAIKHESRHEARPGPMRLRPHAYHNGPSRAGYVASENGQWATDDIPDNLNSIHTAPGEFRAIMEMPSFYSPTLPRCSPYKKLTECQLKNPVSGLLEYAQFTSQTCDFNLIEQSGPSHEPRFKFQVVINGREFPPAEAGSKKVAKQDAAVKAMAILLREAKAKDSGQPEDLSHCPMEEDSEKPAEAQAPSSSATSLFSGKSPVTTLLECMHKLGNSCEFRLLSKEGPAHDPKFQYCVAVGAQTFPPVSAPSKKVAKQMAAEEAMKALQEEAASSADDQSGGANTDSLDESMAPNKIRRIGELVRYLNTNPVGGLLEYARSHGFAAEFKLIDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQDAADAALRVLIGESEKAEQLGFAEVTPVTGASLRRTMLLLSRSPDAHPKTLPLSGSTFHDQIAMLSHRCFNALTNSFQPSLLGRKILAAIIMKRDPEDMGVVVSLGTGNRCVKGDSLSLKGETVNDCHAEIISRRGFIRFLYSELMKYNHHTAKNSIFELARGGEKLQIKKTVSFHLYISTAPCGDGALFDKSCSDRAVESTESRHYPVFENPKQGKLRTKVENGEGTIPVESSDIVPTWDGIRLGERLRTMSCSDKILRWNVLGLQGALLTHFLQPVYLKSVTLGYLFSQGHLTRAICCRVTRDGKAFEDGLRYPFIVNHPKVGRVSVYDSKRQSGKTKETSVNWCMADGYDLEILDGTRGTVDGPGKELSRVSKKNIFLQFKKLCSFRARRDLLQLSYGEAKKAARDYDLAKNYFKKSLRDMGYGNWISKPQEEKNFYLCPVPND", "length": 1178 }, "evidence": [ { "id": "A0A8V1AB28", "url": "https://omabrowser.org/oma/group/A0A8V1AB28/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AB28", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB28" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AB28", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB28" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AB28", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB28" } ], "pmid": "" }, { "name": "supraspliceosomal complex", "id": "GO:0044530", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044530", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AB28", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB28" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "RNA processing", "id": "GO:0006396", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006396", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AB28", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB28" } ], "pmid": "" }, { "name": "mRNA modification", "id": "GO:0016556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016556", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AB28", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB28" } ], "pmid": "" }, { "name": "regulatory ncRNA-mediated gene silencing", "id": "GO:0031047", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031047", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AB28", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB28" } ], "pmid": "" }, { "name": "cellular response to virus", "id": "GO:0098586", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098586", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AB28", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB28" } ], "pmid": "" }, { "name": "positive regulation of viral genome replication", "id": "GO:0045070", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045070", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AB28", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB28" } ], "pmid": "" }, { "name": "response to interferon-alpha", "id": "GO:0035455", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035455", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AB28", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB28" } ], "pmid": "" }, { "name": "adenosine to inosine editing", "id": "GO:0006382", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006382", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AB28", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB28" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "tRNA-specific adenosine deaminase activity", "id": "GO:0008251", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008251", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AB28", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB28" } ], "pmid": "" }, { "name": "double-stranded RNA binding", "id": "GO:0003725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003725", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AB28", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB28" } ], "pmid": "" }, { "name": "double-stranded RNA adenosine deaminase activity", "id": "GO:0003726", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003726", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AB28", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB28" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1147, "end_pos": 1149, "annotation": "n_glycosylation_sequon" }, { "start_pos": 285, "end_pos": 287, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AB28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB28" }, { "id": "PS50141", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50141" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "A to I editase", "eco_id": "ECO_0000259", "start_pos": 811, "end_pos": 1148, "start_aa": "Ser", "end_aa": "Phe", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1AB28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB28" }, { "id": "PS50137", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50137" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DRBM", "eco_id": "ECO_0000259", "start_pos": 442, "end_pos": 510, "start_aa": "Asn", "end_aa": "Gln", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1AB28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB28" }, { "id": "PS50139", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50139" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Z-binding", "eco_id": "ECO_0000259", "start_pos": 129, "end_pos": 195, "start_aa": "Ser", "end_aa": "Asn", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1147, "end_pos": 1149 }, { "start_pos": 285, "end_pos": 287 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AB33-1", "uniprot_ac": "A0A8V1AB33", "uniprot_id": "A0A8V1AB33_CHICK", "mass": { "chemical_mass": 76410.0, "monoisotopic_mass": 76410.0 }, "refseq": {}, "gene_names": [ { "name": "LRRC45", "type": "recommended", "evidence": [ { "id": "A0A8V1AB33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB33" } ] } ], "protein_names": [ { "name": "Leucine rich repeat containing 45", "type": "synonym", "evidence": [ { "id": "A0A8V1AB33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB33/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AB33", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB33" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LRRC45", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB33", "locus": { "chromosome": "18", "start_pos": 5619306, "end_pos": 5629751, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029172", "url": "https://www.ensembl.org/id/ENSGALG00010029172" } ] } } ], "crossref": [ { "id": "A0A8V1AB33", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AB33", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AB33", "url": "https://www.orthodb.org/?gene=A0A8V1AB33", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AMD0", "url": "https://www.orthodb.org/?gene=A0A8V1AMD0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23170", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23170", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23170:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23170:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13516", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13516", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1AB33", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB33", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AB33-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB33-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AMD0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMD0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AMD0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMD0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEEFRRAYAKLCAAPQEAVLRRLRERGEAPGRARLDLAEQSLSLETCGALGRLLPGAAHFAEVALGDCGLSEDGVKLLLHGLCSNSTVKSLDLKGNNLRTTGAEALGKLLRQNKSIRSLILEWNSLGVWEEGFSFFCQGLGANNFLQRLDLRNNQINHHGAGELAMALKRNASLQELDLRWNNIGLLGGRALLNCLQSNKTLKKLELAGNNVPSDILKAVEQAMDHNRDRQTILSETQNRTSVLSKEILNLKDEKTKQFLDLMDTIDKQREEIARSGRISAGRVSQLQEALNEQHSIMNSLKAKLQMTEAALALSEQKVHNLGELLSATKQEQASMAERHFAELQQQKQVGWEGADREGKLFRDLSASNEKNLFLRNQVDELEKKCKVQQDQIFQLKQDLTNTTAELKLRAVQAEERLEMEKRRFKQSLEDMESLRLKEVDHLTQHMEASERSMQDRVQRLEAIRIALEEELSQVKAAALTERGHAEEELIKVRNQARLEEQQRVEHLEEKLRLMTEARDEAQNCCLKQKQMVGEAQVKANQLNLHADGLRRRIEELQQDLNSKEQEKVTEVNKVKVELQEQIGHLQAERTAQEGLREKIAALERQLKVLSSNHREALLDKEGEISMLMEKLRMKEADISRMKEEEAQRASILQNAIMAYVQGSSLGTHSLRK", "length": 673, "header": "tr|A0A8V1AB33-1|A0A8V1AB33_CHICK Isoform 1 of Leucine rich repeat containing 45 OS=Gallus gallus OX=9031 GN=LRRC45 PE=4 SV=1 CANONICAL=A0A8V1AB33-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AB33-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB33/entry#A0A8V1AB33-1", "sequence": { "sequence": "MEEFRRAYAKLCAAPQEAVLRRLRERGEAPGRARLDLAEQSLSLETCGALGRLLPGAAHFAEVALGDCGLSEDGVKLLLHGLCSNSTVKSLDLKGNNLRTTGAEALGKLLRQNKSIRSLILEWNSLGVWEEGFSFFCQGLGANNFLQRLDLRNNQINHHGAGELAMALKRNASLQELDLRWNNIGLLGGRALLNCLQSNKTLKKLELAGNNVPSDILKAVEQAMDHNRDRQTILSETQNRTSVLSKEILNLKDEKTKQFLDLMDTIDKQREEIARSGRISAGRVSQLQEALNEQHSIMNSLKAKLQMTEAALALSEQKVHNLGELLSATKQEQASMAERHFAELQQQKQVGWEGADREGKLFRDLSASNEKNLFLRNQVDELEKKCKVQQDQIFQLKQDLTNTTAELKLRAVQAEERLEMEKRRFKQSLEDMESLRLKEVDHLTQHMEASERSMQDRVQRLEAIRIALEEELSQVKAAALTERGHAEEELIKVRNQARLEEQQRVEHLEEKLRLMTEARDEAQNCCLKQKQMVGEAQVKANQLNLHADGLRRRIEELQQDLNSKEQEKVTEVNKVKVELQEQIGHLQAERTAQEGLREKIAALERQLKVLSSNHREALLDKEGEISMLMEKLRMKEADISRMKEEEAQRASILQNAIMAYVQGSSLGTHSLRK", "length": 673, "header": "tr|A0A8V1AB33-1|A0A8V1AB33_CHICK Isoform 1 of Leucine rich repeat containing 45 OS=Gallus gallus OX=9031 GN=LRRC45 PE=4 SV=1 CANONICAL=A0A8V1AB33-1" }, "locus": { "chromosome": "18", "start_pos": 5628778, "end_pos": 5620454, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070494.1", "url": "https://www.ensembl.org/id/ENSGALT00010070494.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043185.1", "url": "https://www.ensembl.org/id/ENSGALP00010043185.1" } ] } }, { "isoform_ac": "A0A8V1AMD0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB33/entry#A0A8V1AMD0-1", "sequence": { "sequence": "MSLLLHHVSRNLEAVRKEKSGGFSRFQRQEVPPSTAPGPQMKVTKQPHSPAEAAPSPRARCPPSPGVKLLLHGLCSNSTVKSLDLKGNNLRTTGAEALGKLLRQNKSIRSLILEWNSLGVWEEGFSFFCQGLGANNFLQRLDLRNNQINHHGAGELAMALKRNASLQELDLRWNNIGLLGGRALLNCLQSNKTLKKLELAGNNVPSDILKAVEQAMDHNRDRQTILSETQNRTSVLSKEILNLKDEKTKQFLDLMDTIDKQREEIARSGRISAGRVSQLQEALNEQHSIMNSLKAKLQMTEAALALSEQKVHNLGELLSATKQEQASMAERHFAELQQQKQEGADREGKLFRDLSASNEKNLFLRNQVDELEKKCKVQQDQIFQLKQDLTNTTAELKLRAVQAEERLEMEKRRFKQSLEDMESLRLKEVDHLTQHMEASERSMQDRVQRLEAIRIALEEELSQVKAAALTERGHAEEELIKVRNQARLEEQQRVEHLEEKLRLMTEARDEAQNCCLKQKQMVGEAQVKANQLNLHADGLRRRIEELQQDLNSKEQEKVTEVNKVKVELQEQIGHLQAERTAQEGLREKIAALERQLKVLSSNHREALLDKEGEISMLMEKLRMKEADISRMKEEEAQRASILQNAIMAYVQGSSLGTHSLRK", "length": 662, "header": "tr|A0A8V1AMD0-1|A0A8V1AB33_CHICK Computationally mapped isoform of Leucine rich repeat containing 45 OS=Gallus gallus OX=9031 GN=LRRC45 PE=4 SV=1 CANONICAL=A0A8V1AB33-1" }, "locus": { "chromosome": "18", "start_pos": 5629552, "end_pos": 5620454, "strand": "+", "evidence": [ { "database": "Ensembl 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}, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AB43-1", "uniprot_ac": "A0A8V1AB43", "uniprot_id": "A0A8V1AB43_CHICK", "mass": { "chemical_mass": 37719.0, "monoisotopic_mass": 37719.0 }, "refseq": {}, "gene_names": [ { "name": "LOC124416959", "type": "recommended", "evidence": [ { "id": "A0A8V1AB43", "database": "UniProtKB", "url": 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The reference sequence was derived from JAENSK010000035.1. 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"url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14003", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14003:SF23", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14003:SF23", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24381", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24381", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24381:SF390", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24381:SF390", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24388", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24388", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24388:SF36", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24388:SF36", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24388:SF96", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24388:SF96", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24390", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24390", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24390:SF260", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24390:SF260", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01352", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01352", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1AB73", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB73", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AB73-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB73-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGI4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGI4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGI4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGI4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AIL2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIL2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AIL2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIL2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AIL8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIL8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AIL8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIL8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AMG2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMG2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AMG2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMG2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSVWHLRLDPLCSAAGPAERGDAFGVPQDFLEGLPSSPDHCRDRQGLSMGEPAGYSYTSAFHLWSSRPAGKQEMAKGHPFQEPVSFAEVAVYFSREEWALLDPAQRALYRDVMLETYHCVASLVPLPVHKPLVITLLEGGKEPWIPDVCSPEKMVEELGPADVTTAMKEDVQKSKVSERQSSCVSEGESRRDVQGALEQGEHFKKPLGNHTGRTARNPLDLSTAQKQHEEVRSKEVCQKRRQNPCDECGKSCESSSDLIVHQHIQTGERPYKCSECEKSFKRSSHLSYHQRIHTGERPYKCPECGKGFTGSSDLSRHQLIHTAERPFKCHECGKTFKSRSDLSRHQRIHTGETPYSCPQCLQSFRSSYDLTHHQCIHKGERPYKCPECGKSFTSNSVLVRHQRIHTGERAFKCPECGKSFKRCSGLTYHQRIHTGERPFKCSECGKGFTSSSGLTYHQGTHTGEKPYSCPQCPKSFTSSSGLSYHQRFHRGERPFKCSECGKGLTSSSGLTYHQRIHRGERPFKCPECGKSFRSSSDLTHHQRIHKGERPFKCPECGKGFTSNSVLVHHQRIHTGETPFKCPKCGKSFTRSSALRCHQRIHRGERPFKCSDCGKGFTSSSDLIYHQCFHIGEKTYRCPECGKGFRSSSHLSVLQLILTQERPFMCSECERTSKAV", "length": 675, "header": "tr|A0A8V1AB73-1|A0A8V1AB73_CHICK Isoform 1 of Zinc finger protein 302 OS=Gallus gallus OX=9031 GN=ZNF302 PE=3 SV=1 CANONICAL=A0A8V1AB73-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AB73-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB73/entry#A0A8V1AB73-1", "sequence": { "sequence": "MSVWHLRLDPLCSAAGPAERGDAFGVPQDFLEGLPSSPDHCRDRQGLSMGEPAGYSYTSAFHLWSSRPAGKQEMAKGHPFQEPVSFAEVAVYFSREEWALLDPAQRALYRDVMLETYHCVASLVPLPVHKPLVITLLEGGKEPWIPDVCSPEKMVEELGPADVTTAMKEDVQKSKVSERQSSCVSEGESRRDVQGALEQGEHFKKPLGNHTGRTARNPLDLSTAQKQHEEVRSKEVCQKRRQNPCDECGKSCESSSDLIVHQHIQTGERPYKCSECEKSFKRSSHLSYHQRIHTGERPYKCPECGKGFTGSSDLSRHQLIHTAERPFKCHECGKTFKSRSDLSRHQRIHTGETPYSCPQCLQSFRSSYDLTHHQCIHKGERPYKCPECGKSFTSNSVLVRHQRIHTGERAFKCPECGKSFKRCSGLTYHQRIHTGERPFKCSECGKGFTSSSGLTYHQGTHTGEKPYSCPQCPKSFTSSSGLSYHQRFHRGERPFKCSECGKGLTSSSGLTYHQRIHRGERPFKCPECGKSFRSSSDLTHHQRIHKGERPFKCPECGKGFTSNSVLVHHQRIHTGETPFKCPKCGKSFTRSSALRCHQRIHRGERPFKCSDCGKGFTSSSDLIYHQCFHIGEKTYRCPECGKGFRSSSHLSVLQLILTQERPFMCSECERTSKAV", "length": 675, "header": "tr|A0A8V1AB73-1|A0A8V1AB73_CHICK Isoform 1 of Zinc finger protein 302 OS=Gallus gallus OX=9031 GN=ZNF302 PE=3 SV=1 CANONICAL=A0A8V1AB73-1" }, "locus": { "chromosome": "18", "start_pos": 679334, "end_pos": 675112, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070534.1", "url": "https://www.ensembl.org/id/ENSGALT00010070534.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043225.1", "url": "https://www.ensembl.org/id/ENSGALP00010043225.1" } ] } }, { "isoform_ac": "A0A8V1AGI4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB73/entry#A0A8V1AGI4-1", "sequence": { "sequence": "MAKGHPFQEPVSFAEVAVYFSREEWALLDPAQRALYRDVMLETYHCVASLVPLPVHKPLVITLLEGGKEPWIPDVCSPEKMVEELGPAADVTTAMKEDVQKSKVSERQSSCVSEGESRRDVQGALEQGEHFKKPLGNHTGRTARNPLDLSTAQKQHEEHIQTGERPYKCSECEKSFKRSSHLSYHQRIHTGERPYKCPECGKGFTGSSDLSRHQLIHTAERPFKCHECGKTFKSRSDLSRHQRIHTGETPYSCPQCLQSFRSSYDLTHHQCIHKGERPYKCPECGKSFTSNSVLVRHQRIHTGERAFKCPECGKSFKRCSGLTYHQRIHTGERPFKCSECGKGFTSSSGLTYHQGTHTGEKPYSCPQCPKSFTSSSGLSYHQRFHRGERPFKCSECGKGLTSSSGLTYHQRIHRGERPFKCPECGKSFRSSSDLTHHQRIHKGERPFKCPECGKGFTSNSVLVHHQRIHTGETPFKCPKCGKSFTRSSALRCHQRIHRGERPFKCSDCGKGFTSSSDLIYHQCFHIGEKTYRCPECGKGFRSSSHLSVLQLILTQERPFMCSECERTSKAV", "length": 571, "header": "tr|A0A8V1AGI4-1|A0A8V1AB73_CHICK Computationally mapped isoform of Zinc finger protein 302 OS=Gallus gallus OX=9031 GN=ZNF302 PE=3 SV=1 CANONICAL=A0A8V1AB73-1" }, "locus": { "chromosome": "18", "start_pos": 679334, "end_pos": 676606, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070536.1", "url": "https://www.ensembl.org/id/ENSGALT00010070536.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043227.1", "url": "https://www.ensembl.org/id/ENSGALP00010043227.1" } ] } }, { "isoform_ac": "A0A8V1AIL2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB73/entry#A0A8V1AIL2-1", "sequence": { "sequence": "MSVWHLRLDPLCSAAGPAERGDAFGVPQDFLEGLPSSPDHCRDRQGLSMGEPGYSYTSAFHLWSSRPAGKQEMAKGHPFQEPVSFAEVAVYFSREEWALLDPAQRALYRDVMLETYHCVASLVPLPVHKPLVITLLEGGKEPWIPDVCSPEKMVEELGPDVTTAMKEDVQKSKVSERQSSCVSEGESRRDVQGALEQGEHFKKPLGNHTGRTARNPLDLSTAQKQHEEVRSKEVCQKRRQNPCDECGKSCESSSDLIVHQHIQTGERPYKCSECEKSFKRSSHLSYHQRIHTGERPYKCPECGKGFTGSSDLSRHQLIHTAERPFKCHECGKTFKSRSDLSRHQRIHTGETPYSCPQCLQSFRSSYDLTHHQCIHKGERPYKCPECGKSFTSNSVLVRHQRIHTGERAFKCPECGKSFKRCSGLTYHQRIHTGERPFKCSECGKGFTSSSGLTYHQGTHTGEKPYSCPQCPKSFTSSSGLSYHQRFHRGERPFKCSECGKGLTSSSGLTYHQRIHRGERPFKCPECGKSFRSSSDLTHHQRIHKGERPFKCPECGKGFTSNSVLVHHQRIHTGETPFKCPKCGKSFTRSSALRCHQRIHRGERPFKCSDCGKGFTSSSDLIYHQCFHIGEKTYRCPECGKGFRSSSHLSVLQLILTQERPFMCSECERTSKAV", "length": 673, "header": "tr|A0A8V1AIL2-1|A0A8V1AB73_CHICK Computationally mapped isoform of Zinc finger protein 302 OS=Gallus gallus OX=9031 GN=ZNF302 PE=3 SV=1 CANONICAL=A0A8V1AB73-1" }, "locus": { "chromosome": "18", "start_pos": 679334, "end_pos": 675112, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070533.1", "url": "https://www.ensembl.org/id/ENSGALT00010070533.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043224.1", "url": "https://www.ensembl.org/id/ENSGALP00010043224.1" } ] } }, { "isoform_ac": "A0A8V1AIL8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB73/entry#A0A8V1AIL8-1", "sequence": { "sequence": "MAKGHPFQEPVSFAEVAVYFSREEWALLDPAQRALYRDVMLETYHCVASLVPLPVHKPLVITLLEGGKEPWIPDVCSPEKMVEELGPDVTTAMKEDVQKSKVSERQSSCVSEGESRRDVQGALEQGEHFKKPLGNHTGRTARNPLDLSTAQKQHEEVRSKEVCQKRRQNPCDECGKSCESSSDLIVHQHIQTGERPYKCSECEKSFKRSSHLSYHQRIHTGERPYKCPECGKGFTGSSDLSRHQLIHTAERPFKCHECGKTFKSRSDLSRHQRIHTGETPYSCPQCLQSFRSSYDLTHHQCIHKGERPYKCPECGKSFTSNSVLVRHQRIHTGERAFKCPECGKSFKRCSGLTYHQRIHTGERPFKCSECGKGFTSSSGLTYHQGTHTGEKPYSCPQCPKSFTSSSGLSYHQRFHRGERPFKCSECGKGLTSSSGLTYHQRIHRGERPFKCPECGKSFRSSSDLTHHQRIHKGERPFKCPECGKGFTSNSVLVHHQRIHTGETPFKCPKCGKSFTRSSALRCHQRIHRGERPFKCSDCGKGFTSSSDLIYHQCFHIGEKTYRCPECGKGFRSSSHLSVLQLILTQERPFMCSECERTSKAV", "length": 601, "header": "tr|A0A8V1AIL8-1|A0A8V1AB73_CHICK Computationally mapped isoform of Zinc finger protein 302 OS=Gallus gallus OX=9031 GN=ZNF302 PE=3 SV=1 CANONICAL=A0A8V1AB73-1" }, "locus": { "chromosome": "18", "start_pos": 679334, "end_pos": 676606, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070538.1", "url": "https://www.ensembl.org/id/ENSGALT00010070538.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043229.1", "url": "https://www.ensembl.org/id/ENSGALP00010043229.1" } ] } }, { "isoform_ac": "A0A8V1AMG2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB73/entry#A0A8V1AMG2-1", "sequence": { "sequence": "MCAAQRRWWKSLAQVRLGGKREGWGWPKLFLSGQYFGYCMLFLAFFCHPAADVTTAMKEDVQKSKVSERQSSCVSEGESRRDVQGALEQGEHFKKPLGNHTGRTARNPLDLSTAQKQHEEVRSKEVCQKRRQNPCDECGKSCESSSDLIVHQHIQTGERPYKCSECEKSFKRSSHLSYHQRIHTGERPYKCPECGKGFTGSSDLSRHQLIHTAERPFKCHECGKTFKSRSDLSRHQRIHTGETPYSCPQCLQSFRSSYDLTHHQCIHKGERPYKCPECGKSFTSNSVLVRHQRIHTGERAFKCPECGKSFKRCSGLTYHQRIHTGERPFKCSECGKGFTSSSGLTYHQGTHTGEKPYSCPQCPKSFTSSSGLSYHQRFHRGERPFKCSECGKGLTSSSGLTYHQRIHRGERPFKCPECGKSFRSSSDLTHHQRIHKGERPFKCPECGKGFTSNSVLVHHQRIHTGETPFKCPKCGKSFTRSSALRCHQRIHRGERPFKCSDCGKGFTSSSDLIYHQCFHIGEKTYRCPECGKGFRSSSHLSVLQLILTQERPFMCSECERTSKAV", "length": 565, "header": "tr|A0A8V1AMG2-1|A0A8V1AB73_CHICK Computationally mapped isoform of Zinc finger protein 302 OS=Gallus gallus OX=9031 GN=ZNF302 PE=3 SV=1 CANONICAL=A0A8V1AB73-1" }, "locus": { "chromosome": "18", "start_pos": 679334, "end_pos": 677640, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070537.1", "url": "https://www.ensembl.org/id/ENSGALT00010070537.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043228.1", "url": "https://www.ensembl.org/id/ENSGALP00010043228.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AB73", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB73" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AB73", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB73" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AB73", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB73" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AB73", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB73" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AB73", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB73" } ], "pmid": "" }, { "name": "developmental process", "id": "GO:0032502", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032502", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AB73", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB73" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 209, "end_pos": 211, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AB73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB73" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 243, "end_pos": 270, "start_aa": "Asn", "end_aa": "Pro", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1AB73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB73" }, { "id": "PS50805", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50805" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "KRAB", "eco_id": "ECO_0000259", "start_pos": 84, "end_pos": 156, "start_aa": "Val", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 209, "end_pos": 211 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AE09-1", "uniprot_ac": "A0A8V1AE09", "uniprot_id": "A0A8V1AE09_CHICK", "mass": { "chemical_mass": 23521.0, "monoisotopic_mass": 23521.0 }, "refseq": { "ac": "XP_015148550", "name": "ras-related protein Rab-43 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015148550" }, "gene_names": [ { "name": "RAB43", "type": "recommended", "evidence": [ { "id": "A0A8V1AE09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE09" } ] }, { "name": "RAB43", "type": "synonym", "evidence": [ { "id": "XP_015148550", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015148550" } ] } ], "protein_names": [ { "name": "Ras-related protein Rab-43", "type": "recommended", "evidence": [ { "id": "A0A8V1AE09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE09/entry#names_and_taxonomy" } ] }, { "name": "3.6.5.2", "type": "synonym", "evidence": [ { "id": "A0A8V1AE09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE09/entry#names_and_taxonomy" } ] }, { "name": "ras-related protein Rab-43 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015148550", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015148550" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052543.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015148550", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015148550" } ] }, { "annotation": "The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. Involved in retrograde transport from the endocytic pathway to the Golgi apparatus. Required for the structural integrity of the Golgi complex. Also controls the anterograde ER-to-Golgi transport of nascent G-protein-coupled receptors (including ADRA2A, ADRA2B, ADRA2C, ADRA1B, ADRB2 and AGTR1) and regulates the ER sorting of GPCR members by virtue of its ability to interact directly. Involved in the transport of Shiga toxin from early and recycling endosomes to the trans-Golgi network. Plays a role in the maturation of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AE09", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE09#function" }, { "database": "UniProtKB", "id": "ARBA00094312", "url": "https://www.uniprot.org/uniprotkb/ARBA00094312#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AE09", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE09" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RAB43", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE09", "locus": { "chromosome": "12", "start_pos": 5274551, "end_pos": 5289088, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027943", "url": "https://www.ensembl.org/id/ENSGALG00010027943" } ] } } ], "crossref": [ { "id": "A0A8V1AE09", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AE09", "database": "AlphaFoldDB", "categories": [] }, { "id": "415970", "url": "https://www.ncbi.nlm.nih.gov/gene/415970", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001806", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001806", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005225", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005225", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050209", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050209", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AB81", "url": "https://www.orthodb.org/?gene=A0A8V1AB81", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AE09", "url": "https://www.orthodb.org/?gene=A0A8V1AE09", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47979", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47979", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00071", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00071", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-6811440", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6811440", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015148550", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015148550", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "19669", "url": "https://www.rhea-db.org/rhea/19669", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1AB81", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB81", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AB81-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB81-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AE09", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE09", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AE09-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE09-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPGPAAPGPGPDPEESYDFLFKLVLIGDASVGKTCLVQRFKTGAFAERQGSTIGVDFTMKSLEIQGKRVKIWDTAGQERFRTITQSYYRSANGAILAYDISKRGSFLSIPRWIEDVRKYAGSNIVQLLIGNKSDLSDLREVQLEEAQSLAERYDNIICAIETSAKDSSNVEEAFVKMATELMMRHGGPMFSEKNTDSIKLDSKDVVEGWGCGC", "length": 213, "header": "tr|A0A8V1AE09-1|A0A8V1AE09_CHICK Isoform 1 of Ras-related protein Rab-43 OS=Gallus gallus OX=9031 GN=RAB43 PE=1 SV=1 CANONICAL=A0A8V1AE09-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AB81-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE09/entry#A0A8V1AB81-1", "sequence": { "sequence": "GRQRHAGPGSAGARSRPRGKLRLPLQAGAHRRRQRGQDLPRTALQNRGLRRAPGQHHRRGLHHEEPGDPGQAGEGNKSDLSDLREVQLEEAQSLAERYDNIICAIETSAKDSSNVEEAFVKMATELMMRHGGPMFSEKNTDSIKLDSKDVVEGWGCGC", "length": 158, "header": "tr|A0A8V1AB81-1|A0A8V1AE09_CHICK Computationally mapped isoform of Ras-related protein Rab-43 OS=Gallus gallus OX=9031 GN=RAB43 PE=1 SV=1 CANONICAL=A0A8V1AE09-1" }, "locus": { "chromosome": "12", "start_pos": 5289017, "end_pos": 5277871, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067730.1", "url": "https://www.ensembl.org/id/ENSGALT00010067730.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041473.1", "url": "https://www.ensembl.org/id/ENSGALP00010041473.1" } ] } }, { "isoform_ac": "A0A8V1AE09-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE09/entry#A0A8V1AE09-1", "sequence": { "sequence": "MPGPAAPGPGPDPEESYDFLFKLVLIGDASVGKTCLVQRFKTGAFAERQGSTIGVDFTMKSLEIQGKRVKIWDTAGQERFRTITQSYYRSANGAILAYDISKRGSFLSIPRWIEDVRKYAGSNIVQLLIGNKSDLSDLREVQLEEAQSLAERYDNIICAIETSAKDSSNVEEAFVKMATELMMRHGGPMFSEKNTDSIKLDSKDVVEGWGCGC", "length": 213, "header": "tr|A0A8V1AE09-1|A0A8V1AE09_CHICK Isoform 1 of Ras-related protein Rab-43 OS=Gallus gallus OX=9031 GN=RAB43 PE=1 SV=1 CANONICAL=A0A8V1AE09-1" }, "locus": { "chromosome": "12", "start_pos": 5289004, "end_pos": 5277871, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067732.1", "url": "https://www.ensembl.org/id/ENSGALT00010067732.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041475.1", "url": "https://www.ensembl.org/id/ENSGALP00010041475.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-GGA-6811440", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6811440", "resource": "Reactome", "description": "Retrograde transport at the Trans-Golgi-Network" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AE09", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE09" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AE09", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE09" } ], "pmid": "" }, { "name": "G protein activity", "id": "GO:0003925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003925", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AE09", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE09" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 8, "go_terms": [ { "name": "phagosome maturation", "id": "GO:0090382", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090382", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AE09", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE09" } ], "pmid": "" }, { "name": "autophagosome assembly", "id": "GO:0000045", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000045", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AE09", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE09" } ], "pmid": "" }, { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AE09", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE09" } ], "pmid": "" }, { "name": "endoplasmic reticulum to Golgi vesicle-mediated transport", "id": "GO:0006888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006888", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AE09", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE09" } ], "pmid": "" }, { "name": "Golgi organization", "id": "GO:0007030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007030", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AE09", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE09" } ], "pmid": "" }, { "name": "virion assembly", "id": "GO:0019068", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019068", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AE09", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE09" } ], "pmid": "" }, { "name": "regulation of Golgi organization", "id": "GO:1903358", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903358", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AE09", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE09" } ], "pmid": "" }, { "name": "retrograde transport, plasma membrane to Golgi", "id": "GO:0035526", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035526", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AE09", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE09" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AE09", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE09" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AE09", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE09" } ], "pmid": "" }, { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AE09", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE09" } ], "pmid": "" }, { "name": "phagocytic vesicle membrane", "id": "GO:0030670", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030670", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AE09", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE09" } ], "pmid": "" }, { "name": "endoplasmic reticulum-Golgi intermediate compartment membrane", "id": "GO:0033116", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033116", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AE09", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE09" } ], "pmid": "" }, { "name": "cis-Golgi network membrane", "id": "GO:0033106", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033106", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AE09", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE09" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 131, "end_pos": 133, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "19669", "name": "", "equation": "GTP + H2O = GDP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YVX9-1", "F1NSA8-1", "R4GJA4-1", "A0A1L1RKZ0-1", "E1BUS1-1", "Q5ZHW4-1", "Q90694-1", "P08070-1", "P09642-1", "P09643-1", "P09644-1", "P09645-1", "Q5F352-1", "Q5ZMS3-1", "Q90705-1", "Q90835-1", "Q90965-1", "Q98932-1", "A0A3Q2UHM4-1", "Q5ZHX1-1", "A0A1D5PT95-1", "E1BQI2-1", "F1NPF0-1", "A0A8V0XVU5-1", "A0A8V0XBX5-1", "A0A8V0Z564-1", "A0A8V0Y9R6-1", "A0A1D5PM27-1", "A0A8V0Z8U4-1", "A0A8V0ZJW2-1", "A0A8V1ABB1-1", "A0A8V0YDX6-1", "E1BWN3-1", "Q5F499-1", "Q5ZKU5-1", "P02552-1", "P08642-1", "P26990-1", "P42558-1", "Q5F470-1", "Q5ZIT5-1", "Q5ZJN2-1", "P50146-1", "A0A8V0ZNW3-1", "A0A8V0YIM0-1", "A0A8V0ZRZ2-1", "A0A8V1A9Z8-1", "Q1KME6-1", "Q5ZLG1-1", "P84172-1", "A0A8V1ACG4-1", "A0A8V0YTL7-1", "A0A3Q2UG55-1", "A0A8V1AIF5-1", "Q5ZHV1-1", "A0A8V0Z5P2-1", "A0A8V0Y4A4-1", "A0A8V0YA62-1", "A0A8V0YVM3-1", "A0A1D5P1F5-1", "A0A8V1ADZ7-1", "F1NWF1-1", "A0A8V1AP30-1", "A0A8V0XDD5-1", "A0A8V0XMC5-1", "A0A8V0YWW1-1", "A0A8V0ZR14-1", "A0A8V0Y2H3-1", "Q5ZJD3-1", "Q5ZM73-1", "Q5ZM83-1", "A0A8V0YTY9-1", "A0A8V0ZXW3-1", "A0A8V1AHB3-1", "A0A8V0YDI7-1", "A0A1D5NV13-1", "A0A8V0XGK7-1", "A0A8V0YHK2-1", "A0A8V0XC33-1", "A0A8V0XKC3-1", "F1P278-1", "A0A8V0ZG00-1", "A0A8V1AGP3-1", "A0A8V1AN75-1", "A0A8V0Z416-1", "A0A8V1A0V4-1", "A0A8V1A8Q7-1", "A0A8V1ABD3-1", "A0A8V1API8-1", "A0A8V0YIU8-1", "A0A8V0X962-1", "A0A8V1AKH3-1", "P79784-1", "A0A1D5P533-1", "A0A8V1A8I5-1", "A0A8V1AE09-1", "Q9PSX7-1", "Q5ZKR4-1", "A0A8V0YGN8-1", "A0A8V0XNL0-1", "A0A8V0Y3H2-1" ], "evidence": [ { "id": "19669", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/19669" } ] }, { "id": "R-GGA-6811431", "name": "RAB6:GTP binds the GARP and COG complexes, t-SNAREs and endosome-derived vesicles", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "trans-Golgi network membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q1KME6-1", "A0A8V1AE09-1" ], "evidence": [ { "id": "R-GGA-6811431", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6811431" } ] }, { "id": "R-GGA-8847534", "name": "RAB43 hydrolyses GTP", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "trans-Golgi network membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V1AE09-1" ], "evidence": [ { "id": "R-GGA-8847534", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8847534" } ] }, { "id": "R-GGA-8847537", "name": "RAB43:GTP binds USP8NL", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "trans-Golgi network membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V1AE09-1" ], "evidence": [ { "id": "R-GGA-8847537", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8847537" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5NV13", "gene_name": "RIT2", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5NV13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NV13" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A1D5NV13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NV13" } ] } ] }, { "uniprot_ac": "A0A1D5P1F5", "gene_name": "RAB40C", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5P1F5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1F5" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A1D5P1F5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1F5" } ] } ] }, { "uniprot_ac": "A0A1D5P533", "gene_name": "RASEF", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5P533", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P533" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A1D5P533", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P533" } ] } ] }, { "uniprot_ac": "A0A1D5PM27", "gene_name": "OPA1", "activity": [ { "ec_number": "3.6.5.5", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5PM27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PM27" } ] }, { "ec_number": "3.6.5.5", "activity": "", "evidence": [ { "id": "A0A1D5PM27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PM27" } ] } ] }, { "uniprot_ac": "A0A1D5PT95", "gene_name": "KRAS", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5PT95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PT95" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A1D5PT95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PT95" } ] } ] }, { "uniprot_ac": "A0A1L1RKZ0", "gene_name": "RASL11AL", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1L1RKZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RKZ0" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A1L1RKZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RKZ0" } ] } ] }, { "uniprot_ac": "A0A3Q2UG55", "gene_name": "RAB9B", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q2UG55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UG55" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A3Q2UG55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UG55" } ] } ] }, { "uniprot_ac": "A0A3Q2UHM4", "gene_name": "DNM1L", "activity": [ { "ec_number": "3.6.5.5", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q2UHM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UHM4" } ] }, { "ec_number": "3.6.5.5", "activity": "", "evidence": [ { "id": "A0A3Q2UHM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UHM4" } ] } ] }, { "uniprot_ac": "A0A8V0X962", "gene_name": "RAB31", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0X962", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X962" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0X962", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X962" } ] } ] }, { "uniprot_ac": "A0A8V0XBX5", "gene_name": "RAP2B", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XBX5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XBX5" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0XBX5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XBX5" } ] } ] }, { "uniprot_ac": "A0A8V0XC33", "gene_name": "RAB23", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XC33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XC33" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0XC33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XC33" } ] } ] }, { "uniprot_ac": "A0A8V0XDD5", "gene_name": "RAB12", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XDD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XDD5" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0XDD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XDD5" } ] } ] }, { "uniprot_ac": "A0A8V0XGK7", "gene_name": "RAB6A", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XGK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XGK7" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0XGK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XGK7" } ] } ] }, { "uniprot_ac": "A0A8V0XKC3", "gene_name": "RAB18", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XKC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XKC3" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0XKC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XKC3" } ] } ] }, { "uniprot_ac": "A0A8V0XMC5", "gene_name": "RAB10L", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XMC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMC5" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0XMC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMC5" } ] } ] }, { "uniprot_ac": "A0A8V0XNL0", "gene_name": "RABL2A", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XNL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNL0" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0XNL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNL0" } ] } ] }, { "uniprot_ac": "A0A8V0XVU5", "gene_name": "RASL11A", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XVU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XVU5" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0XVU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XVU5" } ] } ] }, { "uniprot_ac": "A0A8V0Y2H3", "gene_name": "RAB10", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0Y2H3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2H3" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0Y2H3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2H3" } ] } ] }, { "uniprot_ac": "A0A8V0Y3H2", "gene_name": "GPN1", "activity": [ { "ec_number": "3.6.5.-", "activity": "", "evidence": [ { "id": "A0A8V0Y3H2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3H2" } ] } ] }, { "uniprot_ac": "A0A8V0Y4A4", "gene_name": "RAB24", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0Y4A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y4A4" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0Y4A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y4A4" } ] } ] }, { "uniprot_ac": "A0A8V0Y9R6", "gene_name": "RAP1B", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0Y9R6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9R6" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0Y9R6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9R6" } ] } ] }, { "uniprot_ac": "A0A8V0YA62", "gene_name": "RAB28", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YA62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA62" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0YA62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA62" } ] } ] }, { "uniprot_ac": "A0A8V0YDI7", "gene_name": "RAB17", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YDI7", "database": "UniProtKB", "url": 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"database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGN8" } ] } ] }, { "uniprot_ac": "A0A8V0YHK2", "gene_name": "RAC2", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YHK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHK2" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0YHK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHK2" } ] } ] }, { "uniprot_ac": "A0A8V0YIM0", "gene_name": "SAR1B", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YIM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIM0" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0YIM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIM0" } ] } ] }, { "uniprot_ac": "A0A8V0YIU8", "gene_name": "GTPBP1", "activity": [ { "ec_number": "3.6.5.3", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YIU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIU8" } ] }, { "ec_number": "3.6.5.3", "activity": "", "evidence": [ { "id": "A0A8V0YIU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIU8" } ] } ] }, { "uniprot_ac": "A0A8V0YTL7", "gene_name": "DNM3", "activity": [ { "ec_number": "3.6.5.5", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YTL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTL7" } ] }, { "ec_number": "3.6.5.5", "activity": "", "evidence": [ { "id": "A0A8V0YTL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTL7" } ] } ] }, { "uniprot_ac": "A0A8V0YTY9", "gene_name": "EIF5B", "activity": [ { "ec_number": "3.6.5.3", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": 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introns SAMEA103992290, SAMEA103992415 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000315.1. On Sep 23, 2021 this sequence version replaced NP_001264924.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001264924", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264924" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AB83", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB83" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "DHRS7C", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB83", "locus": { "chromosome": "18", "start_pos": 751062, "end_pos": 739616, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029190", "url": "https://www.ensembl.org/id/ENSGALG00010029190" } ] } } ], "crossref": [ { "id": "A0A8V1AB83", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AB83", "database": "AlphaFoldDB", 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"KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MDPVWTT", "url": "https://omabrowser.org/oma/group/MDPVWTT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AB83", "url": "https://www.orthodb.org/?gene=A0A8V1AB83", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR44668", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44668", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR44668:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44668:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00106", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00106", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001264924", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264924", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AB83", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB83", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AB83-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB83-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGILAVFALPLLLLGISGIIYIYQTVIWLVSKSAVQNKVVVITDAISGLGKECSRVFHSGGARLVLCGRTWEKLEALYDALISVADPSTTYTPKLVLLDITDTDYIQDVAKEILNCYGSVDILINNASMKVKGAVQSISLELDKKIMDANYFGPITLTKAILPNMISRRTGQIVLINSIQGKIGVPFRAAYAASKHAAVGFFDCLRAEMEEFDISVSTVNPTFICSYHHQPAPGNWEASIWKFFFRKVTYGVHPAEVAEEVLRTVSSKKQEVLMANPIPRAAVYIRTFFPEMFFAIVASGIREKLKTEQEN", "length": 311, "header": "tr|A0A8V1AB83-1|A0A8V1AB83_CHICK Isoform 1 of Dehydrogenase/reductase SDR family member 7C OS=Gallus gallus OX=9031 GN=DHRS7C PE=3 SV=1 CANONICAL=A0A8V1AB83-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AB83-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB83/entry#A0A8V1AB83-1", "sequence": { "sequence": "MGILAVFALPLLLLGISGIIYIYQTVIWLVSKSAVQNKVVVITDAISGLGKECSRVFHSGGARLVLCGRTWEKLEALYDALISVADPSTTYTPKLVLLDITDTDYIQDVAKEILNCYGSVDILINNASMKVKGAVQSISLELDKKIMDANYFGPITLTKAILPNMISRRTGQIVLINSIQGKIGVPFRAAYAASKHAAVGFFDCLRAEMEEFDISVSTVNPTFICSYHHQPAPGNWEASIWKFFFRKVTYGVHPAEVAEEVLRTVSSKKQEVLMANPIPRAAVYIRTFFPEMFFAIVASGIREKLKTEQEN", "length": 311, "header": "tr|A0A8V1AB83-1|A0A8V1AB83_CHICK Isoform 1 of Dehydrogenase/reductase SDR family member 7C OS=Gallus gallus OX=9031 GN=DHRS7C PE=3 SV=1 CANONICAL=A0A8V1AB83-1" }, "locus": { "chromosome": "18", "start_pos": 749222, "end_pos": 740212, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070544.1", "url": "https://www.ensembl.org/id/ENSGALT00010070544.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043235.1", "url": "https://www.ensembl.org/id/ENSGALP00010043235.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:417304", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417304", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AB83", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB83" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AB83", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB83" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "intracellular calcium ion homeostasis", "id": "GO:0006874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006874", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AB83", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB83" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor", "id": "GO:0016616", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016616", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AB83", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB83" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 126, "end_pos": 128, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 126, "end_pos": 128 } ] }, "class_list": 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"total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AB85-1", "uniprot_ac": "A0A8V1AB85", "uniprot_id": "A0A8V1AB85_CHICK", "mass": { "chemical_mass": 88982.0, "monoisotopic_mass": 88982.0 }, "refseq": {}, "gene_names": [ { "name": "DCST2", "type": "recommended", "evidence": [ { "id": "A0A8V1AB85", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB85" } ] } ], "protein_names": [ { "name": "DC-STAMP domain containing 2", "type": "synonym", "evidence": [ { "id": "A0A8V1AB85", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB85/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AB85", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB85" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "DCST2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB85", "locus": { "chromosome": "25", "start_pos": 2059265, "end_pos": 2070416, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027945", "url": "https://www.ensembl.org/id/ENSGALG00010027945" } ] } } ], "crossref": [ { "id": "A0A8V1AB85", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AB85", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR012858", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012858", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051856", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051856", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058842", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058842", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AB85", "url": 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"database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AB85-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB85-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVSMGTGRSIGAAAPASGLGVGDEHQPHTQPTLTGVRGWGWDWGWGGWVGSSHSCWGASASRVAPCVPTAERPLRGTDTDSAPGDPRGDMERLKSAVLGAVLGLGMAFSIKVRLSVLLTLPHVFTREGKILLLLLALGMAVQGPCTNVLHNFARVAESVACGAELALNQTAERMQRAREPLLNVLSKIKDIAQKAKVVGDRVRKFFRAIIDGVTHVARALRNVWLWLSNVGDVCNREMGTPFHRCLRLFSDAKDNCERALSFLFFLCYIIITFKPLCGLASIGLLFCIIPMYIQSFLRRVVAEPINRALDRLRREFEFNISVSHHFDVTLNSSKTLADVAMDIMEGVARRLQPTRQLLGLSAYVSSCAILYMYLQALRYRYRYLRDDTFDNVYITGRFVQMDAQRAQVGRPTVLPLSIRESSRYIHPGMPWLSQQERQRYGLELTGFLRYVLLGLSLVLADYSLFWLLDLVRHQMQGEIVARAPAVLAVSVEGSGYTSDIYRDVVSSFDVLQRGNVSVLSQRCLVQPVEPDYGTYISMGILYGICFFIALCGSHVARLRRVVCAAYYPTREQERTVFLYNRILARRKGLVHALHRAARQSAADAGGSILLRFLGSRVPGFTPLLQLLGTQQKCCLACGAMEQKGLHTCITVGCKGLYCSQCYATLNNVCSVCMGPLSYKDMGDEEIDSSDEETPELWLGALRALRGQEQQQLRDQGRQLEESIRRVVRGRGGGRRLPPKIAARLRAQLEEKEEERGGDDDDDVGGEDSSASSLDFSYQEQPEGSGSELEEVRAERPHGRTR", "length": 801, "header": "tr|A0A8V1AB85-1|A0A8V1AB85_CHICK Isoform 1 of DC-STAMP domain containing 2 OS=Gallus gallus OX=9031 GN=DCST2 PE=4 SV=1 CANONICAL=A0A8V1AB85-1" }, "isoforms": [ { 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Isoform 1 of DC-STAMP domain containing 2 OS=Gallus gallus OX=9031 GN=DCST2 PE=4 SV=1 CANONICAL=A0A8V1AB85-1" }, "locus": { "chromosome": "25", "start_pos": 2070395, "end_pos": 2059433, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067735.1", "url": "https://www.ensembl.org/id/ENSGALT00010067735.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041478.1", "url": "https://www.ensembl.org/id/ENSGALP00010041478.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "sperm-egg recognition", "id": "GO:0035036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035036", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AB85", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB85" } ], "pmid": "" }, { "name": "fusion of sperm to egg plasma membrane involved in 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"publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AB92", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB92" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "peptidase inhibitor activity", "id": "GO:0030414", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030414", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AB92", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB92" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 143, "end_pos": 145, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], 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product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000323.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001376649", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376649" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AB93", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB93" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MRM1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB93", "locus": { "chromosome": "19", "start_pos": 8682270, "end_pos": 8675754, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029196", "url": "https://www.ensembl.org/id/ENSGALG00010029196" } ] } } ], "crossref": [ { "id": "A0A8V1AB93", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AB93", "database": "AlphaFoldDB", 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"InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047182", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047182", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047261", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047261", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "QVPPYEY", "url": "https://omabrowser.org/oma/group/QVPPYEY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AB93", "url": "https://www.orthodb.org/?gene=A0A8V1AB93", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46103", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46103", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46103:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46103:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00588", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00588", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08032", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08032", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001376649", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376649", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AB93", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB93", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AB93-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB93-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MERALRSLARRALGLPSTARSRCFGEGPTRDQQPSRLCTAAARGGDGARTFRGGLHAAREGWGSAGREASKGRRRPEGRALPIERTRGSEILFGVAPCSMALSQARRDLFRLFLKRSGGPQRLVTSEFVLQAAARGVPVLHVGRRELDTLCGGRVHQGVCLEATPLRFKRLEEAEEPGLGDGESPNRQLLWLALEQIQDPMNLGALLRSAYFLGVDRVVTSQRNSCPLTPTVSKASSGAMEVFDVYSTDDLRSFLKAKAAEGWEVVGTVSQSETVENVPVISCLEFRWNKPIILVIGSEGDGLSLETQLLCHQMLVIPSGRALHPGIESLNVSVATGILLHSICSQKLRNSD", "length": 352, "header": "tr|A0A8V1AB93-1|A0A8V1AB93_CHICK Isoform 1 of rRNA methyltransferase 1, mitochondrial OS=Gallus gallus OX=9031 GN=MRM1 PE=3 SV=1 CANONICAL=A0A8V1AB93-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AB93-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB93/entry#A0A8V1AB93-1", "sequence": { "sequence": "MERALRSLARRALGLPSTARSRCFGEGPTRDQQPSRLCTAAARGGDGARTFRGGLHAAREGWGSAGREASKGRRRPEGRALPIERTRGSEILFGVAPCSMALSQARRDLFRLFLKRSGGPQRLVTSEFVLQAAARGVPVLHVGRRELDTLCGGRVHQGVCLEATPLRFKRLEEAEEPGLGDGESPNRQLLWLALEQIQDPMNLGALLRSAYFLGVDRVVTSQRNSCPLTPTVSKASSGAMEVFDVYSTDDLRSFLKAKAAEGWEVVGTVSQSETVENVPVISCLEFRWNKPIILVIGSEGDGLSLETQLLCHQMLVIPSGRALHPGIESLNVSVATGILLHSICSQKLRNSD", "length": 352, "header": "tr|A0A8V1AB93-1|A0A8V1AB93_CHICK Isoform 1 of rRNA methyltransferase 1, mitochondrial OS=Gallus gallus OX=9031 GN=MRM1 PE=3 SV=1 CANONICAL=A0A8V1AB93-1" }, "locus": { "chromosome": "19", "start_pos": 8681570, "end_pos": 8675946, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070555.1", "url": "https://www.ensembl.org/id/ENSGALT00010070555.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043246.1", "url": "https://www.ensembl.org/id/ENSGALP00010043246.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 29, "start_aa": "Thr", "end_pos": 29, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr29", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A5G2R9B5-1", "protein_name": "rRNA methyltransferase 1, mitochondrial", "gene_name": "MRM1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MELLSAARGATWRCCGRLLTRPFSQAARRGDRPGGEELSRLLLDDLALPPRSAGGLELLFGLSPCLLALRAARRRVARLLLQAGRSGLQGERAELLRVAEARDIPVLRPRRRKLDVLCRYQVHQGVCMEVSPLRPQPWAEAGESRPGDDPQQLWLVLEGLQDPRNLGAVLRSAHFLGVEKVITSRKNSCPLTPVVSKASAGAMEVMDVFSTDDLAGFLQAKARQGWLVAGTVGCPGPEISPSSEVPITSCLDFLWDQPTLLVLGNEGSGLSREVQASCQLLLTILPGRQLPPGLESLNVSVAAGILLHSICSQRKGFPVEQKREQHLLQDPQEPWPLSEGPSLTQHPGLCSGSAKQRQDGD", "length": 361 }, "evidence": [ { "id": "A0A8V1AB93", "url": "https://omabrowser.org/oma/group/A0A8V1AB93/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8C2QCQ5-1", "protein_name": "rRNA methyltransferase 1, mitochondrial", "gene_name": "Mrm1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MRLLWTVGCFGILTARHFSPVARPGGEELSRLLLDDLPPTQRLERLFGLSPCLLALRAARRRVARLLLQAGKAGLQGERAELLRVAEARGIPVLRPRRQKLDALCGHQVHQGVCMEVSPLRPRLCDDEAAEASPGDDPQQLWLVLEGLQDPRNLGAVLRSAHFLGVDRVITSRRNSCPLTPVVSKASAGAVEVMDVFATSDLAGFLKAKAQQGWLVVGTVGCPGPEISHSTKVPITSCLEFIWDRPTLLVLGNEGSGLSQEVLASCQLLLTILPRRHLPPGLESLNVSVATGILLHSICSQKKSFPVQTEKGQLLQDT", "length": 318 }, "evidence": [ { "id": "A0A8V1AB93", "url": "https://omabrowser.org/oma/group/A0A8V1AB93/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "D3ZK81-1", "protein_name": "rRNA methyltransferase 1, mitochondrial", "gene_name": "Mrm1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLLLWTVGCFNRLVARHFSSVARPGERPGGEELSRLLLDDLAPAQRLERLFGVSPCLLALRAARRHVARLLLQAGKAGLQGERAELLRVAEARGIPVLRPRRQKLDALCGYQVHQGVCMEVSRLRPRPCDEAADTSSGDDPQQLWLVLEGIQDPRNLGAVMRSAYFLGVDRVITSRRNSCPLTPVVSKASAGAMEVMDVFASPDLASFLQAKAQQGWLVVGTVGCPGPEISQSSKVPVTSCLEFIWDRPTLLVLGNEGSGLSQGVFATCQLLLTILPGRHLPPGLESLNVSVATGILLHSICSQKKGFPVQERGQRLQDS", "length": 320 }, "evidence": [ { "id": "A0A8V1AB93", "url": "https://omabrowser.org/oma/group/A0A8V1AB93/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6IN84-1", "protein_name": "rRNA methyltransferase 1, mitochondrial", "gene_name": "MRM1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MALLSTVRGATWGRLVTRHFSHAARHGERPGGEELSRLLLDDLVPTSRLELLFGMTPCLLALQAARRSVARLLLQAGKAGLQGKRAELLRMAEARDIPVLRPRRQKLDTMCRYQVHQGVCMEVSPLRPRPWREAGEASPGDDPQQLWLVLDGIQDPRNFGAVLRSAHFLGVDKVITSRRNSCPLTPVVSKSSAGAMEVMDVFSTDDLTGFLQTKAQQGWLVAGTVGCPSTEDPQSSEIPIMSCLEFLWERPTLLVLGNEGSGLSQEVQASCQLLLTILPRRQLPPGLESLNVSVAAGILLHSICSQRKGFPTEGERRQLLQDPQEPSARSEGLSMAQHPGLSSGPEKERQNEG", "length": 353 }, "evidence": [ { "id": "A0A8V1AB93", "url": "https://omabrowser.org/oma/group/A0A8V1AB93/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q99J25-1", "protein_name": "rRNA methyltransferase 1, mitochondrial", "gene_name": "Mrm1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRRLWTVGCFSRLIARHFSSVARRGERPGGEELSRLLLDDLAPAQRLERLFGLSPCLLALRAARRRVARLLLQAGKAGLQGERAELLRVAEARGIPVLRPRRQKLDALCGYQVHQGVCMEVSPLRPRPCDEAADTSSGDDPQQLWLVLEGLQDPRNLGAVMRSAHFLGVDRVITSQRNSCPLTPVVSKASAGAMEVMDVFATPDLPGFLQAKAQQGWLVVGTVGCPGPEISQSSKVPITSCLEFVWDRPTLLVLGSEGSGLSQEVFASCQLLLTILPRRHLPPGLESLNVSVATGILLHSICSQKKGFPVQERGQLLQDS", "length": 320 }, "evidence": [ { "id": "A0A8V1AB93", "url": "https://omabrowser.org/oma/group/A0A8V1AB93/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "rRNA (guanine) methyltransferase activity", "id": "GO:0016435", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016435", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AB93", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB93" } ], "pmid": "" }, { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AB93", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB93" } ], "pmid": "" }, { "name": "rRNA (guanosine-2'-O-)-methyltransferase activity", "id": "GO:0070039", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070039", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AB93", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB93" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "rRNA modification", "id": "GO:0000154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000154", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AB93", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB93" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AB93", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB93" } ], "pmid": "" }, { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AB93", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB93" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 331, "end_pos": 333, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AB93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB93" }, { "id": "SM00967", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00967" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RNA 2-O ribose methyltransferase substrate binding", "eco_id": "ECO_0000259", "start_pos": 91, "end_pos": 169, "start_aa": "Ile", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 29 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 331, "end_pos": 333 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1ABA2-1", "uniprot_ac": "A0A8V1ABA2", "uniprot_id": "A0A8V1ABA2_CHICK", "mass": { "chemical_mass": 102102.0, "monoisotopic_mass": 102102.0 }, "refseq": { "ac": "XP_015154633", "name": "RNA-binding protein 15", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015154633" }, "gene_names": [ { "name": "RBM15", "type": "recommended", "evidence": [ { "id": "A0A8V1ABA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABA2" } ] }, { "name": "RBM15", "type": "synonym", "evidence": [ { "id": "XP_015154633", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015154633" } ] } ], "protein_names": [ { "name": "RNA-binding protein 15", "type": "recommended", "evidence": [ { "id": "A0A8V1ABA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABA2/entry#names_and_taxonomy" } ] }, { "name": "One-twenty two protein 1", "type": "synonym", "evidence": [ { "id": "A0A8V1ABA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABA2/entry#names_and_taxonomy" } ] }, { "name": "RNA-binding motif protein 15", "type": "synonym", "evidence": [ { "id": "A0A8V1ABA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABA2/entry#names_and_taxonomy" } ] }, { "name": "RNA-binding protein 15", "type": "synonym", "evidence": [ { "id": "XP_015154633", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015154633" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052557.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015154633.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015154633", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015154633" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABA2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABA2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RBM15", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABA2", "locus": { "chromosome": "26", "start_pos": 1455270, "end_pos": 1436082, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027328", "url": "https://www.ensembl.org/id/ENSGALG00010027328" } ] } } ], "crossref": [ { "id": "A0A8V1ABA2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1ABA2", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd12553", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12553", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12555", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12555", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd21549", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21549", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100859595", "url": "https://www.ncbi.nlm.nih.gov/gene/100859595", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010912", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010912", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012921", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012921", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016194", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016194", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034470", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034470", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034472", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034472", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:100859595", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100859595", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "EWPNPAI", "url": "https://omabrowser.org/oma/group/EWPNPAI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ABA2", "url": "https://www.orthodb.org/?gene=A0A8V1ABA2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23189", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23189", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00076", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00076", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07744", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07744", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015154633", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015154633", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1ABA2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABA2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ABA2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABA2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKGKERSPAKAKRSRGGGGGEDSASSSSSARGERSSKKPSGSGGGGGSNGGKAAAAAASNDSNSGSSRRGPHPDKAARAGSREYESGAAAAATGGGGGRHSYGGKSAEPSRSSSSRGGESRAAVAAQSSSSSETGGGGEYKTLKISELGSALSDEAVEDGLFHEFKRFGDVSVKISRLPPGTGAADERVAFVNFRRPEDARAAKHARGRLVLYDRPLKIEAVYVGSGGGSSRRRSSRSPALLDKESPYGTAAVGLAAAAAAVRHPAAGATQRALSPAGSGGALGYRDYRLQQLALGRLPPPPPLPRELERERDYGGFYEARVRPAYGLERVASVAAAGGFRGGGGGAGAAGEEEISPEDDQRANRTLFLGNLDITVSETDLRRAFDRFGVITEVDIKRPGRGQTSTYGFLKFENLDMAHRAKLAMSGKVLLRNPIKIGYGKATPTTRLWVGGLGPWVPLAALAREFDRFGTIRTIDYRKGDSWAYIQYESLDAAQAACTHMRGFPLGGPDRRLRVDFADTEHRYQQPYLQPLPLPPPAHYELVAEAAAFGAHRGAPPDPLRGARDRTPPLLYRDRDRDLYPETEWVPPPPPVRDRSNRAAAYDPLESLERRRDGWSLERDRGERELGSSRDQPRKRRLAEDGGRHLDRSPDSERSSSSRKRHCLTTTTPPDRSPELVGGRERYSSDPERSSSRLLLLERPSPIRESRRGSLERGQNEKRDRKNSAERERKHRTSAAATAQECKSPAKKDERAAEGGGGGSRLKPPPQKQQQDGASQAGGAPKLCLAWQGMLLLKNSNFPSNMHLLQGDLGVASSLLVEGATGGKVAQLKITQRLRLDQPKLDEVNRRIKVAGPNGYAILLAVPGTSDNRSAAGAGEAATTSTQRPLRNLVSYLKQKQAAGVISLPVGGNKDKENSGVLHAFPPCDFSQQFLDSTAKALAKSEDDYLVMIIVRGAS", "length": 955, "header": "tr|A0A8V1ABA2-1|A0A8V1ABA2_CHICK Isoform 1 of RNA-binding protein 15 OS=Gallus gallus OX=9031 GN=RBM15 PE=1 SV=1 CANONICAL=A0A8V1ABA2-1" }, "isoforms": [ { "isoform_ac": "A0A8V1ABA2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABA2/entry#A0A8V1ABA2-1", "sequence": { "sequence": "MKGKERSPAKAKRSRGGGGGEDSASSSSSARGERSSKKPSGSGGGGGSNGGKAAAAAASNDSNSGSSRRGPHPDKAARAGSREYESGAAAAATGGGGGRHSYGGKSAEPSRSSSSRGGESRAAVAAQSSSSSETGGGGEYKTLKISELGSALSDEAVEDGLFHEFKRFGDVSVKISRLPPGTGAADERVAFVNFRRPEDARAAKHARGRLVLYDRPLKIEAVYVGSGGGSSRRRSSRSPALLDKESPYGTAAVGLAAAAAAVRHPAAGATQRALSPAGSGGALGYRDYRLQQLALGRLPPPPPLPRELERERDYGGFYEARVRPAYGLERVASVAAAGGFRGGGGGAGAAGEEEISPEDDQRANRTLFLGNLDITVSETDLRRAFDRFGVITEVDIKRPGRGQTSTYGFLKFENLDMAHRAKLAMSGKVLLRNPIKIGYGKATPTTRLWVGGLGPWVPLAALAREFDRFGTIRTIDYRKGDSWAYIQYESLDAAQAACTHMRGFPLGGPDRRLRVDFADTEHRYQQPYLQPLPLPPPAHYELVAEAAAFGAHRGAPPDPLRGARDRTPPLLYRDRDRDLYPETEWVPPPPPVRDRSNRAAAYDPLESLERRRDGWSLERDRGERELGSSRDQPRKRRLAEDGGRHLDRSPDSERSSSSRKRHCLTTTTPPDRSPELVGGRERYSSDPERSSSRLLLLERPSPIRESRRGSLERGQNEKRDRKNSAERERKHRTSAAATAQECKSPAKKDERAAEGGGGGSRLKPPPQKQQQDGASQAGGAPKLCLAWQGMLLLKNSNFPSNMHLLQGDLGVASSLLVEGATGGKVAQLKITQRLRLDQPKLDEVNRRIKVAGPNGYAILLAVPGTSDNRSAAGAGEAATTSTQRPLRNLVSYLKQKQAAGVISLPVGGNKDKENSGVLHAFPPCDFSQQFLDSTAKALAKSEDDYLVMIIVRGAS", "length": 955, "header": "tr|A0A8V1ABA2-1|A0A8V1ABA2_CHICK Isoform 1 of RNA-binding protein 15 OS=Gallus gallus OX=9031 GN=RBM15 PE=1 SV=1 CANONICAL=A0A8V1ABA2-1" }, "locus": { "chromosome": "26", "start_pos": 1439069, "end_pos": 1436205, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066253.1", "url": "https://www.ensembl.org/id/ENSGALT00010066253.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040519.1", "url": "https://www.ensembl.org/id/ENSGALP00010040519.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:100859595", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100859595", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2L987-1", "protein_name": "RNA-binding protein 15", "gene_name": "Rbm15", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MRSAGREPLPRRSPRWRRASPLCETSAGWRVSQLRRDDLRRPSTMKGKERSPVKPKRSRGGEDSSSRGERSKKLGGSGGSNGSSSGKTDSGGSRRSLHLDKSSSRGGSREYDTGGGSSSSRLHSYSSPSTKNSSGGGESRSSSRGGGGESRSSGAASSAPGGGDGVEYKTLKISELGSQLSDEAVEDGLFHEFKRFGDVSVKISHLSGSGSGDERVAFVNFRRPEDARAAKHARGRLVLYDRPLKIEAVYVSRRRSRSPLDKDTYPPSSSVVGTSVGSHRHAPGGGGGQRSLSPGGAALGYRDYRLQQLALGRLPPPPPPPLPRELERERDYPFYDRVRPAYSLEPRVGAGAGAAPFREVDEISPEDDQRANRTLFLGNLDITVTENDLRRAFDRFGVITEVDIKRPSRGQTSTYGFLKFENLDMSHRAKLAMSGKIIIRNPIKIGYGKATPTTRLWVGGLGPWVPLAALAREFDRFGTIRTIDYRKGDSWAYIQYESLDAAHAAWTHMRGFPLGGPDRRLRVDFADTEHRYQQQYLQPLPLTHYELVTDTFGHRAPDPLRSARDRTPPLLYRDRDRDLYTDSDWVPPPPPVRERSARAAASAVTAYEPLDSLDRRRDGWSLDRDRGDRDLPSSRDQPRKRRLPEESGGRHLDRSPESDRPRKRHCTPSPDRSPELSSNRDRYNSDNDRSSRLLLERPSPIRDRRGSLEKSQSDKRDRKNSASAERDRKHRTAAPTEGKNPLKKEERSDGNAPSASASSSKQKAPSQKQDGGTAPVAASSPKLCLAWQGMLLLKNSNFPSNMHLLQGDLQVASSLLVEGSTGGKVAQLKITQRLRLDQPKLDEVTRRIKVAGPNGYAILLAVPGSSDSRSSSSSATSDTATSTQRPLRNLVSYLKQKQAAGVISLPVGGNKDKENTGVLHAFPPCEFSQQFLDSPAKALAKSEEDYLVMIIVRAKLVNSG", "length": 960 }, "evidence": [ { "id": "A0A8V1ABA2", "url": "https://omabrowser.org/oma/group/A0A8V1ABA2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "F1RCY7-1", "protein_name": "RNA-binding protein 15", "gene_name": "rbm15", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MKGKERSPVKKRSRALDDIRDRGGSHPTSKKMGVISNSGGGSNNGNSSSKSDGGSARRGLLGDKRDGREFDGHVSSRTGNNHGYTSPVASSSGKNHASSLSLEAARTNSRGEARAPLPTNESEYKTLKISELGSQLSDEEIEDGLFHEFKKFGDVSVKISRVNDERIAFVNFRRPDDARAAKHARGRLVLYDRPLKIEAVYLNRRRSRSPVKEDHFSVVAGHRHLHTQRPLSPTGLGYRDYRLQQLALGRLPPPPPPPLPRELEREREFAFYEARARPAYIAERAAPFREEDFISPEDDQRANRTLFLGNLDITVTENDLRRAFERFGTITEVDIKRPTRGQSSTYGFLKFENLDMAHRAKISMSGKVVGRNPIKIGYGKATPTTRLWVGGLGPWVPLTALAREFDRFGTIRTIDYRKGDTWAYIQYESLDAAQAACTHMRGFPLGGPDRRLRVDFADTEHRYQQQFLQPLPLQHYEIMAESFVHRATPEAIRVRERTPPPLHFRERELYAGAEWPAPTIRERVRTPAFEPLEHLERERRREAWSLERELPGREAARKRRLMEDGRHLECSPDSSSEWAARRRRPPSLEGSPGGSSRDGRFSDSERPARADRVSPARESRSSLDRVPGEKRIKSNSNLSESSIGASPAERKRKAGDSAKGASKRDRSESSSKSNQASKQDAGGKLSMAWNGMLLLKNSNFPASMHLLEGDLSVATSLLIDGSTGGKVSQLRITQRLRLDQPKIDEVSRRIKVAGPGGYAVLLAVPGSSEETSSSDPAASTQRPLRNLVSYLKQKQAAGVISLPVGGSRDKDNTGVLHAFPPCDFSQQFLDSSAKALAKTEEDFLVMIVVRGAS", "length": 853 }, "evidence": [ { "id": "A0A8V1ABA2", "url": "https://omabrowser.org/oma/group/A0A8V1ABA2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1S619-1", "protein_name": "RNA-binding protein 15", "gene_name": "RBM15", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MKTAGRDPLPRRSPRWRRAVPLCETSAGRRVNQLRGEDLRRPATMKGKERSPVKPKRSRGGEDSTSRGERSKKLGGSGGSNGSSSGKTDSGGGSRRSLHLDKSSSRGGSREYETGGGSSSSRLHSYSSPSTKNSSGGGESRSSSRGGGGESRSSGAASSAPGGGDGGEYKTLKISELGSQLSDEAVEDGLFHEFKRFGDVSVKISHLSGSGSGDERVAFVNFRRPEDARAAKHARGRLVLYDRPLKIEAVYVSRRRSRSPLDKDSYPPSASVVGSSVGGHRHPPGGGGGGQRSLSPGGAALGYRDYRLQQLALGRLPPPPPPPLPRELERERDYPFYERVRPAYSLEPRVGAGAGAAPFRDVDEISPEDDQRANRTLFLGNLDITVTESDLRRAFDRFGVITEVDIKRPSRGQTSTYGFLKFENLDMSHRAKLAMSGKIIIRNPIKIGYGKATPTTRLWVGGLGPWVPLAALAREFDRFGTIRTIDYRKGDSWAYIQYESLDAAHAAWTHMRGFPLGGPDRRLRVDFADTEHRYQQQYLQPLPLTHYELVTDAFGHRAPDPLRGARDRTPPLLYRDRDRDLYPDSDWVPPPPPVRERSTRTAATAVPAYEPLDSLDRRRDGWSLDRDRGERDLPSSRDQPRKRRLPEESGGRHLDRSPENDRPRKRHCAPSPDRSPELSSSRDRYNSDNDRSSRLLLLERPSPVRDRRGSLEKSQGDKRDRKNSASAERDRKHRTTASTEGKSPLKKEDRSDGSAPSTSTASSKLKSPSQKQDGGTAPAAAASPKLCLAWQGMLLLKNSNFPSNMHLLQGDLQVASSLLVEGSTGGKVAQLKITQRLRLDQPKLDEVTRRIKVAGPNGYAILLAVPGNSDSRSSSSSATSDTATSTQRPLRNLVSYLKQKQAAGVISLPVGGNKDKENTGVLHAFPPCEFSQQFLDSPAKALAKSEEDYLVMIIVRAKLVNNG", "length": 963 }, "evidence": [ { "id": "A0A8V1ABA2", "url": "https://omabrowser.org/oma/group/A0A8V1ABA2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "M0R3Z8-1", "protein_name": "RNA-binding protein 15", "gene_name": "Rbm15", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRSAGREPLPRRSPRWRRASPLCETSAGWRVSQLRRDDLRRPSTMKGKERSPVKPKRSRGGEDSSSRGERSKKLGGSGGSNGSSSGKTDSGGSRRSLHLDKSSSRGGSREYDTGGGSSSSRLHSYSSPSTKNSSGGGESRSSSRGGGGESRSSGAASSAPGGGDGVEYKTLKISELGSQLSDEAVEDGLFHEFKRFGDVSVKISHLSGSGSGDERVAFVNFRRPEDARAAKHARGRLVLYDRPLKIEAVYVSRRRSRSPLDKDTYAPSSSVVGSSVGSHRHAPGGGGGQRSLSPGGAALGYRDYRLQQLALGRLPPPPPPPLPRELERERDYPFYDRVRPAYSLEPRVGAGAGAAPFREVDEISPEDDQRANRTLFLGNLDITVTENDLRRAFDRFGVITEVDIKRPSRGQTSTYGFLKFENLDMSHRAKIAMSGKIIIRNPIKIGYGKATPTTRLWVGGLGPWVPLAALAREFDRFGTIRTIDYRKGDSWAYIQYESLDAAHAAWTHMRGFPLGGPDRRLRVDFADTEHRYQQQYLQPLPLTHYELVTDTFGHRAPDPLRSARDRTPPLLYRDRDRDLYPDSDWVPPPPPVRERSARAATSAVTAYEPLDSLDRRRDGWSLDRDRGDRDLPSSRDQPRKRRLPEESGGRHLDRSPESDRPRKQRHCTPSPDRSPELSSNRDRYNSDNDRSSRLLLLERPSPVRDRRGSLEKSQSDKRDRKNSASAERDRKHRTAAPTEGKTPLKKEDRSDGNTPSASTSSSKQKPPSQKQDGGTAPVAASSPKLCLAWQGMLLLKNSNFPSNMHLLQGDLQVASSLLVEGSTGGKVAQLKITQRLRLDQPKLDEVTRRIKVAGPNGYAILLAVPGSSDSRSSSSSATSDTAASTQRPLRNLVSYLKQKQAAGVISLPVGGNKDKENTGVLHAFPPCEFSQQFLDSPAKALAKSEEDYLVMIIVRAKLVNIG", "length": 962 }, "evidence": [ { "id": "A0A8V1ABA2", "url": "https://omabrowser.org/oma/group/A0A8V1ABA2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q0VBL3-1", "protein_name": "RNA-binding protein 15", "gene_name": "Rbm15", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRSAGREPLPRRSPRWRRASPLCETSAGWRVSQLRRDDLRRPSTMKGKERSPVKPKRSRGGEDSSSRGERSKKLGGSGGSNGSSSGKTDSGGSRRSLHLDKSSSRGGSREYETGGGSSSSRLHSYSSPSTKNSSGGGESRSSSRGGGGESRSSGAASSAPGGGDGVEYKTLKISELGSQLSDEAVEDGLFHEFKRFGDVSVKISHLSGSGSGDERVAFVNFRRPEDARAAKHARGRLVLYDRPLKIEAVYVSRRRSRSPLDKDAYAPSSSVVGTSVGSHRHAPGGGGGQRSLSPGGAALGYRDYRLQQLALGRLPPPPPPPLPRELERERDYPFYDRVRPAYSLEPRVGAGAGAAPFREVDEISPEDDQRANRTLFLGNLDITVTENDLRRAFDRFGVITEVDIKRPSRGQTSTYGFLKFENLDMSHRAKLAMSGKIIIRNPIKIGYGKATPTTRLWVGGLGPWVPLAALAREFDRFGTIRTIDYRKGDSWAYIQYESLDAAHAAWTHMRGFPLGGPDRRLRVDFADTEHRYQQQYLQPLPLTHYELVTDTFGHRAPDPLRSARDRTPPLLYRDRDRDLYTDSDWVPPPPPVRERSARAATSAVTAYEPLDSLDRRRDGWSLDRDRGDRDLPSSRDQPRKRRLPEESGGRHLDRSPESERPRKQRHCTPSPDRSPELSSNRDRYNSDNDRSSRLLLLERSSPVRDRRGSLEKSQSDKRDRKNSASAERDRKHRTAAPTEGKNPLKKEDRSDGNAPSASTSSSKQKPPSQKQDGGTAPVAASSPKLCLAWQGMLLLKNSNFPSNMHLLQGDLQVASSLLVEGSTGGKVAQLKITQRLRLDQPKLDEVTRRIKVAGPNGYAILLAVPGSSDSRSSSSSATSDTAASTQRPLRNLVSYLKQKQAAGVISLPVGGNKDKENTGVLHAFPPCEFSQQFLDSPAKALAKSEEDYLVMIIVRAKLVNSG", "length": 962 }, "evidence": [ { "id": "A0A8V1ABA2", "url": "https://omabrowser.org/oma/group/A0A8V1ABA2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7KMJ6-1", "protein_name": "RNA-binding protein spenito", "gene_name": "nito", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSSHRDGAGADRITIKIHNMKRSASRSPGPASRSSLSRNSRSMGRGYDNGSGVPGDSPERLSPERMRRRLDRSPSRYGSPHREPYMRGPPPAERPAGYKVLCVSALPPKAPDDFIEETLYREYKKFGDFSVRLAHDLDERVAYVCFRTPEDAREAKHHKPRLIIYDKMAIVEPVYKSTTRPEYRPRGHSMSPPDYERYHYSRSPMGQGVPLDHRRPPIDPYDRYGPPHMHPHAVHPRDYRPLHHDYPHPPRGPPLHRGGHPHHLHGHAPPHQYAPMRPLAPRPHAPYEKPESKKDKFPNYLHHVQPEDDPLSTRTLFAGNLEVTIADDELRRIFGKYGVVDDIDIKRPPPGTGNAFAFVRYQNLDMAHRAKIELSGQYIGKFQCKIGYGKVTPATRMWIGGLGAWTSVTQLEREFDRFGAIKKIEYQKGEPYAYIQYETVEAATAAVKEMRGFPLGGPERRLRTDFAELPGATPAAPFKSSKPPYDESALEYRRPEYDPYYEESAAYAPRGGYSPYPPRGGYRGRGGYRGRGRGMYHYHNDVHRPPHPGSLAGSSSSVPPPGGVEDEWRRPPGESYDRGARSSSREPGVERSRSRSPLKRARSPGSDSDTSTRRNDALASASTVPDVARKCSTVWTGALILKSSLFPAKFHLTDGDTDIVESLMRDEEGKHNLRITQRLRLDPPKLDDVQKRIASSSSHAIFMGLAGSTNDTNCDDASVQTRPLRNLVSYLKQKEAAGVISLLNKETEATGVLYAFPPCDFSTELLKRTCHSLTEEGLKEDHLVIVVVRGGTA", "length": 793 }, "evidence": [ { "id": "A0A8V1ABA2", "url": "https://omabrowser.org/oma/group/A0A8V1ABA2/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q96T37-1", "protein_name": "RNA-binding protein 15", "gene_name": "RBM15", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRTAGRDPVPRRSPRWRRAVPLCETSAGRRVTQLRGDDLRRPATMKGKERSPVKAKRSRGGEDSTSRGERSKKLGGSGGSNGSSSGKTDSGGGSRRSLHLDKSSSRGGSREYDTGGGSSSSRLHSYSSPSTKNSSGGGESRSSSRGGGGESRSSGAASSAPGGGDGAEYKTLKISELGSQLSDEAVEDGLFHEFKRFGDVSVKISHLSGSGSGDERVAFVNFRRPEDARAAKHARGRLVLYDRPLKIEAVYVSRRRSRSPLDKDTYPPSASVVGASVGGHRHPPGGGGGQRSLSPGGAALGYRDYRLQQLALGRLPPPPPPPLPRDLERERDYPFYERVRPAYSLEPRVGAGAGAAPFREVDEISPEDDQRANRTLFLGNLDITVTESDLRRAFDRFGVITEVDIKRPSRGQTSTYGFLKFENLDMSHRAKLAMSGKIIIRNPIKIGYGKATPTTRLWVGGLGPWVPLAALAREFDRFGTIRTIDYRKGDSWAYIQYESLDAAHAAWTHMRGFPLGGPDRRLRVDFADTEHRYQQQYLQPLPLTHYELVTDAFGHRAPDPLRGARDRTPPLLYRDRDRDLYPDSDWVPPPPPVRERSTRTAATSVPAYEPLDSLDRRRDGWSLDRDRGDRDLPSSRDQPRKRRLPEESGGRHLDRSPESDRPRKRHCAPSPDRSPELSSSRDRYNSDNDRSSRLLLERPSPIRDRRGSLEKSQGDKRDRKNSASAERDRKHRTTAPTEGKSPLKKEDRSDGSAPSTSTASSKLKSPSQKQDGGTAPVASASPKLCLAWQGMLLLKNSNFPSNMHLLQGDLQVASSLLVEGSTGGKVAQLKITQRLRLDQPKLDEVTRRIKVAGPNGYAILLAVPGSSDSRSSSSSAASDTATSTQRPLRNLVSYLKQKQAAGVISLPVGGNKDKENTGVLHAFPPCEFSQQFLDSPAKALAKSEEDYLVMIIVRGFGFQIGVRYENKKRENLALTLL", "length": 977 }, "evidence": [ { "id": "A0A8V1ABA2", "url": "https://omabrowser.org/oma/group/A0A8V1ABA2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "RNA N6-methyladenosine methyltransferase complex", "id": "GO:0036396", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036396", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABA2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABA2" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABA2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABA2" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABA2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABA2" } ], "pmid": "" }, { "name": "nuclear membrane", "id": "GO:0031965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031965", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABA2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABA2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABA2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABA2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "regulation of megakaryocyte differentiation", "id": "GO:0045652", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045652", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABA2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABA2" } ], "pmid": "" }, { "name": "RNA methylation", "id": "GO:0001510", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001510", "evidence": [ { "database": 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"table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1ABD3-1", "uniprot_ac": "A0A8V1ABD3", "uniprot_id": "A0A8V1ABD3_CHICK", "mass": { "chemical_mass": 28754.0, "monoisotopic_mass": 28754.0 }, "refseq": {}, "gene_names": [ { "name": "RAB36", "type": "recommended", "evidence": [ { "id": "A0A8V1ABD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABD3" } ] } ], "protein_names": [ { "name": "Ras-related protein Rab-36", "type": "recommended", "evidence": [ { "id": "A0A8V1ABD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABD3/entry#names_and_taxonomy" } ] }, { "name": "3.6.5.2", "type": "synonym", "evidence": [ { "id": "A0A8V1ABD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABD3/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABD3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABD3#function" }, { "database": "UniProtKB", "id": "ARBA00058763", "url": "https://www.uniprot.org/uniprotkb/ARBA00058763#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABD3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABD3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RAB36", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABD3", "locus": { "chromosome": "15", "start_pos": 8686049, "end_pos": 8693825, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010026559", "url": "https://www.ensembl.org/id/ENSGALG00010026559" } ] } } ], "crossref": [ { "id": "A0A8V1ABD3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1ABD3", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR001806", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001806", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005225", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005225", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050227", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050227", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ABD3", "url": "https://www.orthodb.org/?gene=A0A8V1ABD3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47977", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47977", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00071", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00071", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-6811438", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6811438", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "19669", "url": "https://www.rhea-db.org/rhea/19669", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1ABD3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABD3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ABD3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABD3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "CASALLPSNPNYPFSLTRWYTPEACLQFKDHFHAQLRTACQQSTGTTGLKISKVVVVGDVYVGKTSLIHRFCKDRFERDYKATIGVDFEIERFEIVGIPYNLQIWDTAGQEKFKCIASAYYRGAEVIITVFDLADIQTLDHTKQWLEDALRENEANSIFIFLVGTKKDLVSDAVCERTELDAIRFANDMQAEYWSVSAKTGENVKEFFSRVAALAFEQSMIRELEKTTGHMAQIGTGNLIRMLSFACLYFAFL", "length": 253, "header": "tr|A0A8V1ABD3-1|A0A8V1ABD3_CHICK Isoform 1 of Ras-related protein Rab-36 OS=Gallus gallus OX=9031 GN=RAB36 PE=3 SV=1 CANONICAL=A0A8V1ABD3-1" }, "isoforms": [ { "isoform_ac": "A0A8V1ABD3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABD3/entry#A0A8V1ABD3-1", "sequence": { "sequence": "CASALLPSNPNYPFSLTRWYTPEACLQFKDHFHAQLRTACQQSTGTTGLKISKVVVVGDVYVGKTSLIHRFCKDRFERDYKATIGVDFEIERFEIVGIPYNLQIWDTAGQEKFKCIASAYYRGAEVIITVFDLADIQTLDHTKQWLEDALRENEANSIFIFLVGTKKDLVSDAVCERTELDAIRFANDMQAEYWSVSAKTGENVKEFFSRVAALAFEQSMIRELEKTTGHMAQIGTGNLIRMLSFACLYFAFL", "length": 253, "header": "tr|A0A8V1ABD3-1|A0A8V1ABD3_CHICK Isoform 1 of Ras-related protein Rab-36 OS=Gallus gallus OX=9031 GN=RAB36 PE=3 SV=1 CANONICAL=A0A8V1ABD3-1" }, "locus": { "chromosome": "15", "start_pos": 8693825, "end_pos": 8686052, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010064522.1", "url": "https://www.ensembl.org/id/ENSGALT00010064522.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039555.1", "url": "https://www.ensembl.org/id/ENSGALP00010039555.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-GGA-6811438", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6811438", "resource": "Reactome", "description": "Intra-Golgi traffic" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABD3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABD3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABD3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABD3" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABD3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABD3" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABD3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABD3" } ], "pmid": "" }, { "name": "G protein activity", "id": "GO:0003925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003925", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABD3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABD3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABD3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABD3" } ], "pmid": "" }, { "name": "vesicle-mediated transport", "id": "GO:0016192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016192", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABD3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABD3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "19669", "name": "", "equation": "GTP + H2O = GDP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YVX9-1", "F1NSA8-1", "R4GJA4-1", "A0A1L1RKZ0-1", "E1BUS1-1", "Q5ZHW4-1", "Q90694-1", "P08070-1", "P09642-1", "P09643-1", "P09644-1", "P09645-1", "Q5F352-1", "Q5ZMS3-1", "Q90705-1", "Q90835-1", "Q90965-1", "Q98932-1", "A0A3Q2UHM4-1", "Q5ZHX1-1", "A0A1D5PT95-1", "E1BQI2-1", "F1NPF0-1", "A0A8V0XVU5-1", "A0A8V0XBX5-1", "A0A8V0Z564-1", "A0A8V0Y9R6-1", "A0A1D5PM27-1", "A0A8V0Z8U4-1", "A0A8V0ZJW2-1", "A0A8V1ABB1-1", "A0A8V0YDX6-1", "E1BWN3-1", "Q5F499-1", "Q5ZKU5-1", "P02552-1", "P08642-1", "P26990-1", "P42558-1", "Q5F470-1", "Q5ZIT5-1", "Q5ZJN2-1", "P50146-1", "A0A8V0ZNW3-1", "A0A8V0YIM0-1", "A0A8V0ZRZ2-1", "A0A8V1A9Z8-1", "Q1KME6-1", "Q5ZLG1-1", "P84172-1", "A0A8V1ACG4-1", "A0A8V0YTL7-1", "A0A3Q2UG55-1", "A0A8V1AIF5-1", "Q5ZHV1-1", "A0A8V0Z5P2-1", "A0A8V0Y4A4-1", "A0A8V0YA62-1", "A0A8V0YVM3-1", "A0A1D5P1F5-1", "A0A8V1ADZ7-1", "F1NWF1-1", "A0A8V1AP30-1", "A0A8V0XDD5-1", "A0A8V0XMC5-1", "A0A8V0YWW1-1", "A0A8V0ZR14-1", "A0A8V0Y2H3-1", "Q5ZJD3-1", "Q5ZM73-1", "Q5ZM83-1", "A0A8V0YTY9-1", "A0A8V0ZXW3-1", "A0A8V1AHB3-1", "A0A8V0YDI7-1", "A0A1D5NV13-1", "A0A8V0XGK7-1", "A0A8V0YHK2-1", "A0A8V0XC33-1", "A0A8V0XKC3-1", "F1P278-1", "A0A8V0ZG00-1", "A0A8V1AGP3-1", "A0A8V1AN75-1", "A0A8V0Z416-1", "A0A8V1A0V4-1", "A0A8V1A8Q7-1", "A0A8V1ABD3-1", "A0A8V1API8-1", "A0A8V0YIU8-1", "A0A8V0X962-1", "A0A8V1AKH3-1", "P79784-1", "A0A1D5P533-1", "A0A8V1A8I5-1", "A0A8V1AE09-1", "Q9PSX7-1", "Q5ZKR4-1", "A0A8V0YGN8-1", "A0A8V0XNL0-1", "A0A8V0Y3H2-1" ], "evidence": [ { "id": "19669", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/19669" } ] }, { "id": "R-GGA-8849748", "name": "The COG complex binds RABs at the Golgi membrane", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "Golgi membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1NWF1-1", "A0A8V1ABD3-1" ], "evidence": [ { "id": "R-GGA-8849748", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8849748" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5NV13", "gene_name": "RIT2", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5NV13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NV13" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A1D5NV13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NV13" } ] } ] }, { "uniprot_ac": "A0A1D5P1F5", "gene_name": "RAB40C", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5P1F5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1F5" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A1D5P1F5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1F5" } ] } ] }, { "uniprot_ac": "A0A1D5P533", "gene_name": "RASEF", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5P533", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P533" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A1D5P533", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P533" } ] } ] }, { "uniprot_ac": "A0A1D5PM27", "gene_name": "OPA1", "activity": [ { "ec_number": "3.6.5.5", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5PM27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PM27" } ] }, { "ec_number": "3.6.5.5", 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] } ] }, { "uniprot_ac": "A0A3Q2UG55", "gene_name": "RAB9B", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q2UG55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UG55" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A3Q2UG55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UG55" } ] } ] }, { "uniprot_ac": "A0A3Q2UHM4", "gene_name": "DNM1L", "activity": [ { "ec_number": "3.6.5.5", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q2UHM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UHM4" } ] }, { "ec_number": "3.6.5.5", "activity": "", "evidence": [ { "id": "A0A3Q2UHM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UHM4" } ] } ] }, { "uniprot_ac": "A0A8V0X962", "gene_name": "RAB31", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + 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##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052549.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040505648", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040505648" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABI4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABI4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TOM1L1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABI4", "locus": { "chromosome": "18", "start_pos": 6467587, "end_pos": 6446283, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029234", "url": "https://www.ensembl.org/id/ENSGALG00010029234" } ] } } ], "crossref": [ { "id": "A0A8V1ABI4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1ABI4", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd14237", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14237", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd16997", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16997", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "417391", "url": "https://www.ncbi.nlm.nih.gov/gene/417391", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002014", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002014", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004152", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004152", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008942", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008942", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014645", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014645", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027428", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027428", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038425", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038425", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047013", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047013", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "FMHICDL", "url": "https://omabrowser.org/oma/group/FMHICDL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ABI4", "url": "https://www.orthodb.org/?gene=A0A8V1ABI4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AIW6", "url": "https://www.orthodb.org/?gene=A0A8V1AIW6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AMP3", "url": "https://www.orthodb.org/?gene=A0A8V1AMP3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13856", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13856", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13856:SF28", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13856:SF28", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00790", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00790", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03127", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03127", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040505648", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040505648", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1ABI4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABI4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ABI4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABI4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AIW6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIW6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AIW6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIW6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AMP3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMP3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AMP3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMP3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAFGKAPKDPFGTAVGSLVERATFGSLQTEEWGQFMHICDVINATEEGPKDAVKALKKKLSKNCNHKEIRLTLSAMDRFHTVKLLDMCMQNCGPRFQSLVVKKDFCKDKLVKLLNPRYNLPIDLQEKILTFIMIWARGFQGMVDVTEVKEVYLELLKKGVEFPSSDTSKGRPKQSPSPAKSSPSSANPPKRSLLPLPTGPTLLLTPEQIGKLYSELDMAKMNVRVMSSILKENVPGSENPDDMNLLQKLYKTCRMMQERIMELLVTVENEDVIVELIQVNEDLNNVLLGHERFSRNRVRFLENQRIQREREELYRKQPSAPSSDLLDLSTDSPSPVAAVLGTDPAASQFPSPNSMSAHPEDRKRLHPSIYPQLDLAAAAKAQQFPFAAEAQNNSVSTPAGHTYSNLATLLSPVPLNPVNQQAGYTASSNGPSPAAASKNKLQSPHYYEIMEFDPLAPTEAIYEEIDAAVLKPEAEKHSQC", "length": 480, "header": "tr|A0A8V1ABI4-1|A0A8V1ABI4_CHICK Isoform 1 of Target of myb1 like 1 membrane trafficking protein OS=Gallus gallus OX=9031 GN=TOM1L1 PE=1 SV=1 CANONICAL=A0A8V1ABI4-1" }, "isoforms": [ { "isoform_ac": "A0A8V1ABI4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABI4/entry#A0A8V1ABI4-1", "sequence": { "sequence": "MAFGKAPKDPFGTAVGSLVERATFGSLQTEEWGQFMHICDVINATEEGPKDAVKALKKKLSKNCNHKEIRLTLSAMDRFHTVKLLDMCMQNCGPRFQSLVVKKDFCKDKLVKLLNPRYNLPIDLQEKILTFIMIWARGFQGMVDVTEVKEVYLELLKKGVEFPSSDTSKGRPKQSPSPAKSSPSSANPPKRSLLPLPTGPTLLLTPEQIGKLYSELDMAKMNVRVMSSILKENVPGSENPDDMNLLQKLYKTCRMMQERIMELLVTVENEDVIVELIQVNEDLNNVLLGHERFSRNRVRFLENQRIQREREELYRKQPSAPSSDLLDLSTDSPSPVAAVLGTDPAASQFPSPNSMSAHPEDRKRLHPSIYPQLDLAAAAKAQQFPFAAEAQNNSVSTPAGHTYSNLATLLSPVPLNPVNQQAGYTASSNGPSPAAASKNKLQSPHYYEIMEFDPLAPTEAIYEEIDAAVLKPEAEKHSQC", "length": 480, "header": "tr|A0A8V1ABI4-1|A0A8V1ABI4_CHICK Isoform 1 of Target of myb1 like 1 membrane trafficking protein OS=Gallus gallus OX=9031 GN=TOM1L1 PE=1 SV=1 CANONICAL=A0A8V1ABI4-1" }, "locus": { "chromosome": "18", "start_pos": 6465688, "end_pos": 6446378, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070652.1", "url": "https://www.ensembl.org/id/ENSGALT00010070652.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043343.1", "url": "https://www.ensembl.org/id/ENSGALP00010043343.1" } ] } }, { "isoform_ac": "A0A8V1AIW6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABI4/entry#A0A8V1AIW6-1", "sequence": { "sequence": "MAFGKAPKDPFGTAVGSLVERATFGSLQTEEWGQFMHICDVINATEEGPKDAVKALKKKLSKNCNHKEIRLTLSLLDMCMQNCGPRFQSLVVKKDFCKDKLVKLLNPRYNLPIDLQEKILTFIMIWARGFQGMVDVTEVKEVYLELLKKGVEFPSSDTSKGRPKQSPSPAKSSPSSANPPKRSLLPLPTGPTLLLTPEQKLYKTCRMMQERIMELLVTVENEDVIVELIQVNEDLNNVLLGHERFSRNRVRFLENQRIQREREELYRKQPSAPSSDLLDLSTDSPSPVAAVLGTDPAASQFPSPNSMSAHPEDRKRLHPSIYPQLDLAAAAKAQQFPFAAEAQNNSVSTPAGHTYSNLATLLSPVPLNPVNQQAGYTASSNGPSPAAASKNKLQSPHYYEIMEFDPLAPTEAIYEEIDAAVLKPEAEKHSQC", "length": 432, "header": "tr|A0A8V1AIW6-1|A0A8V1ABI4_CHICK Computationally mapped isoform of Target of myb1 like 1 membrane trafficking protein OS=Gallus gallus OX=9031 GN=TOM1L1 PE=1 SV=1 CANONICAL=A0A8V1ABI4-1" }, "locus": { "chromosome": "18", "start_pos": 6465688, "end_pos": 6446378, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070651.1", "url": "https://www.ensembl.org/id/ENSGALT00010070651.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043342.1", "url": "https://www.ensembl.org/id/ENSGALP00010043342.1" } ] } }, { "isoform_ac": "A0A8V1AMP3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABI4/entry#A0A8V1AMP3-1", "sequence": { "sequence": "MAFGKAPKDPFGTAVGSLVERATFGSLQTEEWGQFMHICDVINATEEGPKDAVKALKKKLSKNCNHKEIRLTLSLLDMCMQNCGPRFQSLVVKKDFCKDKLVKLLNPRYNLPIDLQEKILTFIMIWARGFQGMVDVTEVKEVYLELLKKGVEFPSSDTSKGRPKQSPSPAKSSPSSANPPKRSLLPLPTGPTLLLTPEQIGKLYSELDMAKMNVRVMSSILKENVPGSENPDDMNLLQKLYKTCRMMQERIMELLVTVENEDVIVELIQVNEDLNNVLLGHERFSRNRVRFLENQRIQREREELYRKQPSAPSSDLLDLSTDSPSPVAAVLGTDPAASQFPSPNSMSAHPEDRKRLHPSIYPQLDLAAAAKAQQFPFAAEAQNNSVSTPAGHTYSNLATLLSPVPLNPVNQQAGYTASSNGPSPAAASKNKLQSPHYYEIMEFDPLAPTEAIYEEIDAAVLKPEAEKHSQC", "length": 471, "header": "tr|A0A8V1AMP3-1|A0A8V1ABI4_CHICK Computationally mapped isoform of Target of myb1 like 1 membrane trafficking protein OS=Gallus gallus OX=9031 GN=TOM1L1 PE=1 SV=1 CANONICAL=A0A8V1ABI4-1" }, "locus": { "chromosome": "18", "start_pos": 6465688, "end_pos": 6446378, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070653.1", "url": "https://www.ensembl.org/id/ENSGALT00010070653.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043344.1", "url": "https://www.ensembl.org/id/ENSGALP00010043344.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2LY01-1", "protein_name": "TOM1-like protein 1 isoform X1", "gene_name": "Tom1l1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAFGKSHRDPYATSVGHLVEKATFAGVQTEDWGQFMHICDIINTTQDGPKDAVKALKKRISKNYNHKEIQLSLSLIDMCMQNCGPSFQSLIVKKEFIKDALVKLLNPRYTLPLDIQNRILNFIKTWSQGFPGGVDVSEVKEVYLDLLKKGVQFPPSDADTETRQEAAQLSPHRPTPVPTAPALSSIIAPKTPTISLVPEQIGKLHSELDMVKMNVKVMTAILMENTPGSENHEDIELLQKLYKTGREMQERIMDLLVVVENEDVTVELIQVNEDLNNAILGYERFTRNQQRLLEQNRNSKDATDTSNEPSAPSCDLLDLSPIVPMPMSNGEALHTVNSQLSALSVSSPSPVVTNSLYPSLHPQVDLLASENTELPSLFAQRTSPNLASSHTYDNFLEHSSSVLLQPVSLQTATAAPASQRLPTLPSNHPVITNNDLQPPNYYEVMEFDPLAPATEAVYEEIDDYHHKGAQSHSDC", "length": 475 }, "evidence": [ { "id": "A0A8V1ABI4", "url": "https://omabrowser.org/oma/group/A0A8V1ABI4/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "O75674-1", "protein_name": "TOM1-like protein 1", "gene_name": "TOM1L1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAFGKSHRDPYATSVGHLIEKATFAGVQTEDWGQFMHICDIINTTQDGPKDAVKALKKRISKNYNHKEIQLTLSLIDMCVQNCGPSFQSLIVKKEFVKENLVKLLNPRYNLPLDIQNRILNFIKTWSQGFPGGVDVSEVKEVYLDLVKKGVQFPPSEAEAETARQETAQISSNPPTSVPTAPALSSVIAPKNSTVTLVPEQIGKLHSELDMVKMNVRVMSAILMENTPGSENHEDIELLQKLYKTGREMQERIMDLLVVVENEDVTVELIQVNEDLNNAILGYERFTRNQQRILEQNKNQKEATNTTSEPSAPSQDLLDLSPSPRMPRATLGELNTMNNQLSGLNFSLPSSDVTNNLKPSLHPQMNLLALENTEIPPFAQRTSQNLTSSHAYDNFLEHSNSVFLQPVSLQTIAAAPSNQSLPPLPSNHPAMTKSDLQPPNYYEVMEFDPLAPAVTTEAIYEEIDAHQHKGAQNDGD", "length": 476 }, "evidence": [ { "id": "A0A8V1ABI4", "url": "https://omabrowser.org/oma/group/A0A8V1ABI4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q923U0-1", "protein_name": "TOM1-like protein 1", "gene_name": "Tom1l1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAFGKSHRDPYATSVGHLIEKATFAGVLTEDWGQFLHICDIINTTQDGPKDAVKALKKRISKNYNHKEIQLSLSLIDMCVQNCGPSFQSLIVKKEFIKDTLVKLLNPRYTLPLETQNRILNFIKTWSQGFPGGVDVSEVKEVYLDLLKKGVQFPPSDGEPETRQEAGQISPNRPTSVPTAPALSSIIAPKNPTISLVPEQIGKLHSELDMVKMNVKVMTAILMENTPGSENHEDIELLRKLYKTGREMQERIMDLLVVVENEDVTMELIQVNEDLNNAVLGYERFTRNQQRLLEQKRNRTEATRTSSEPSAPSCDLLDLSPIVPVPTPNEGALNSVNAQLSGLSVSSLSPVITNNLYPSLQPQRDLLASEDIEIPTLFPQRTSQNLASSHTYDNFHSNSVLLQPVSLHTATAAAAANQRLPPLPSSHPVLKDGDLQPPNYYEVMEFDPLAPTTEAVYEEIDGYHQKEAQSHSDC", "length": 474 }, "evidence": [ { "id": "A0A8V1ABI4", "url": "https://omabrowser.org/oma/group/A0A8V1ABI4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "endosome", "id": "GO:0005768", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005768", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABI4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABI4" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABI4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABI4" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABI4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABI4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABI4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABI4" } ], "pmid": "" }, { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABI4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABI4" } ], "pmid": "" }, { "name": "negative regulation of mitotic nuclear division", "id": "GO:0045839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045839", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABI4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABI4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABI4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABI4" } ], "pmid": "" }, { "name": "protein kinase activator activity", "id": "GO:0030295", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030295", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABI4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABI4" } ], "pmid": "" }, { "name": "clathrin binding", "id": "GO:0030276", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030276", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABI4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABI4" } ], "pmid": "" }, { "name": "phosphatidylinositol binding", "id": "GO:0035091", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035091", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABI4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABI4" } ], "pmid": "" }, { "name": "ubiquitin binding", "id": "GO:0043130", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043130", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABI4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABI4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 392, "end_pos": 394, "annotation": "n_glycosylation_sequon" }, { "start_pos": 43, "end_pos": 45, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1ABI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABI4" }, { "id": "PS50909", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50909" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "GAT", "eco_id": "ECO_0000259", "start_pos": 207, "end_pos": 295, "start_aa": "Glu", "end_aa": "Arg", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1ABI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABI4" }, { "id": "PS50179", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50179" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "VHS", "eco_id": "ECO_0000259", "start_pos": 22, "end_pos": 163, "start_aa": "Ala", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 392, "end_pos": 394 }, { "start_pos": 43, "end_pos": 45 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1ABJ6-1", "uniprot_ac": "A0A8V1ABJ6", "uniprot_id": "A0A8V1ABJ6_CHICK", "mass": { "chemical_mass": 124166.0, "monoisotopic_mass": 124166.0 }, "refseq": { "ac": "XP_015155410", "name": "rho GTPase-activating protein 45 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015155410" }, "gene_names": [ { "name": "ARHGAP45", "type": "recommended", "evidence": [ { "id": "A0A8V1ABJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABJ6" } ] }, { "name": "ARHGAP45", "type": "synonym", "evidence": [ { "id": "XP_015155410", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015155410" } ] }, { "name": "HMHA1", "type": "synonym", "evidence": [ { "id": "XP_015155410", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015155410" } ] } ], "protein_names": [ { "name": "Rho GTPase activating protein 45", "type": "synonym", "evidence": [ { "id": "A0A8V1ABJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABJ6/entry#names_and_taxonomy" } ] }, { "name": "rho GTPase-activating protein 45 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015155410", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015155410" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052559.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015155410.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015155410", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015155410" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABJ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABJ6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ARHGAP45", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABJ6", "locus": { "chromosome": "28", "start_pos": 3367759, "end_pos": 3354693, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027984", "url": "https://www.ensembl.org/id/ENSGALG00010027984" } ] } } ], "crossref": [ { "id": "A0A8V1ABJ6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1ABJ6", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd20816", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20816", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "420102", "url": "https://www.ncbi.nlm.nih.gov/gene/420102", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000198", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000198", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001060", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001060", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002219", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002219", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008936", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008936", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027267", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027267", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031160", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031160", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046349", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046349", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051025", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051025", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR054713", "url": "https://www.ebi.ac.uk/interpro/entry/IPR054713", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057028", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057028", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PLACLCR", "url": "https://omabrowser.org/oma/group/PLACLCR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ABJ6", "url": "https://www.orthodb.org/?gene=A0A8V1ABJ6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AEC7", "url": "https://www.orthodb.org/?gene=A0A8V1AEC7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AED7", "url": "https://www.orthodb.org/?gene=A0A8V1AED7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AGW5", "url": "https://www.orthodb.org/?gene=A0A8V1AGW5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15228", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15228", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15228:SF18", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15228:SF18", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00130", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00130", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00620", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00620", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22699", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22699", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24235", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24235", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-6798695", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-8980692", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8980692", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9013148", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013148", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9013149", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013149", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015155410", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015155410", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1ABJ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABJ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ABJ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABJ6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AEC7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEC7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AEC7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEC7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AED7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AED7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AED7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AED7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGW5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGW5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGW5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGW5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLGRAAGRNSYSPYAAGRRRTGKATSPKHSLDSLPRSPSVRLTDLSRKDCLEAPSPGELPPTSVKLSSSPSAVGTLKRPTSLSRHASAAGFPLTSAGPRAVPKGHKTPTSYSPMEGGEGLFIDVEDISQLLTDVARFADALENLRDVVLRDDPKESQRPQAHECLGETLRVLRQVINKYPLLNTLETLTAAGTLISKVKGFHYESNNETDKREFEKAVETIAVSFSSTVSEFLMGEVDSSTILSIPPSDQNQSMESLYGGIPGPGGDGVPSGMESYDTVRPAAEEVDVMLQRCEGGVDAALQYAKNISKYMKDLIGYLEKRTALEMEFAKGLQKMANSCKQTFTQETSMPFLSIYLLALEQDMEYGMSVLQTVTTLQHQTFLQPLTVRRLEHEKRRKEIKEQWHRAQRKLQDAEVNLRKAKQVYMQRSEEHDKAKYVTVKAEEEQQSTASSITTKTLDKKRRLEEEAKNKAEEAMATYRTCVADANTQKQELEDTKVNSLRQIHELIKQSDQVIKLATIAFYQIMHMQTAPLPVYFQTLCESSKLYDPGQQYASHVKQLQRGDEPDTQYDFEPYVSHSAWSPFTRARKGSFNASDFSSSGGSDGAGLPRDGSSTEGPRETQGGTLAERRAGRGHQVHKSWPTSTSEADSSLDSSTAGEFGHKLQRLSSNGTMSSSEELGEKDENATSFEQSINGITPEMTAPTGPFRNVGLSRAAQTHRLRKLRAPSKCRECNSYVYFQGAECEECYLACHKKCLETLAIQCGHKKLQGKLQLFGQDFLKASQGSADGIPFIVKKCISEIEKRALKTKGIYRVNGVKTRVEKLCQAFENGKELVELSQASPHDISNVLKLYLRQLPEPIVPFRMYNALMGAAKESLQGGSDAKGRSGKGGPELMDRGADTDRVVVNLVLKLKELLKELPWENTATLRYLLQHLRRIVEVEQDNKMTSSNLGIVFGPTLLRPRPTDATISLSSLVDYPHQARVIEALIIFYPTIFEDKDSKLTAEGSEFSADREEDTPDEPTAAPCPQPPGKGDLGYSVGAFGEPSERSVDSDSELEDGGEPAGSGQLRKQESETSTDEAPFYEEGSEGQRSRTCSTGQSDTEGAALRCAAGEHSDPEEDPESSAAQQ", "length": 1127, "header": "tr|A0A8V1ABJ6-1|A0A8V1ABJ6_CHICK Isoform 1 of Rho GTPase activating protein 45 OS=Gallus gallus OX=9031 GN=ARHGAP45 PE=1 SV=1 CANONICAL=A0A8V1ABJ6-1" }, "isoforms": [ { "isoform_ac": "A0A8V1ABJ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABJ6/entry#A0A8V1ABJ6-1", "sequence": { "sequence": "MLGRAAGRNSYSPYAAGRRRTGKATSPKHSLDSLPRSPSVRLTDLSRKDCLEAPSPGELPPTSVKLSSSPSAVGTLKRPTSLSRHASAAGFPLTSAGPRAVPKGHKTPTSYSPMEGGEGLFIDVEDISQLLTDVARFADALENLRDVVLRDDPKESQRPQAHECLGETLRVLRQVINKYPLLNTLETLTAAGTLISKVKGFHYESNNETDKREFEKAVETIAVSFSSTVSEFLMGEVDSSTILSIPPSDQNQSMESLYGGIPGPGGDGVPSGMESYDTVRPAAEEVDVMLQRCEGGVDAALQYAKNISKYMKDLIGYLEKRTALEMEFAKGLQKMANSCKQTFTQETSMPFLSIYLLALEQDMEYGMSVLQTVTTLQHQTFLQPLTVRRLEHEKRRKEIKEQWHRAQRKLQDAEVNLRKAKQVYMQRSEEHDKAKYVTVKAEEEQQSTASSITTKTLDKKRRLEEEAKNKAEEAMATYRTCVADANTQKQELEDTKVNSLRQIHELIKQSDQVIKLATIAFYQIMHMQTAPLPVYFQTLCESSKLYDPGQQYASHVKQLQRGDEPDTQYDFEPYVSHSAWSPFTRARKGSFNASDFSSSGGSDGAGLPRDGSSTEGPRETQGGTLAERRAGRGHQVHKSWPTSTSEADSSLDSSTAGEFGHKLQRLSSNGTMSSSEELGEKDENATSFEQSINGITPEMTAPTGPFRNVGLSRAAQTHRLRKLRAPSKCRECNSYVYFQGAECEECYLACHKKCLETLAIQCGHKKLQGKLQLFGQDFLKASQGSADGIPFIVKKCISEIEKRALKTKGIYRVNGVKTRVEKLCQAFENGKELVELSQASPHDISNVLKLYLRQLPEPIVPFRMYNALMGAAKESLQGGSDAKGRSGKGGPELMDRGADTDRVVVNLVLKLKELLKELPWENTATLRYLLQHLRRIVEVEQDNKMTSSNLGIVFGPTLLRPRPTDATISLSSLVDYPHQARVIEALIIFYPTIFEDKDSKLTAEGSEFSADREEDTPDEPTAAPCPQPPGKGDLGYSVGAFGEPSERSVDSDSELEDGGEPAGSGQLRKQESETSTDEAPFYEEGSEGQRSRTCSTGQSDTEGAALRCAAGEHSDPEEDPESSAAQQ", "length": 1127, "header": "tr|A0A8V1ABJ6-1|A0A8V1ABJ6_CHICK Isoform 1 of Rho GTPase activating protein 45 OS=Gallus gallus OX=9031 GN=ARHGAP45 PE=1 SV=1 CANONICAL=A0A8V1ABJ6-1" }, "locus": { "chromosome": "28", "start_pos": 3366449, "end_pos": 3356160, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067856.1", "url": "https://www.ensembl.org/id/ENSGALT00010067856.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041599.1", "url": "https://www.ensembl.org/id/ENSGALP00010041599.1" } ] } }, { "isoform_ac": "A0A8V1AEC7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABJ6/entry#A0A8V1AEC7-1", "sequence": { "sequence": "MFSRKKRELMKTPSISKKSRAGSPIPQTLPDLSRKDCLEAPSPGELPPTSVKLSSSPSAVGTLKRPTSLSRHASAAGFPLTSAGPRAVPKGHKTPTSYSPMEGGEGLFIDVEDISQLLTDVARFADALENLRDVVLRDDPKESQRPQAHECLGETLRVLRQVINKYPLLNTLETLTAAGTLISKVKGFHYESNNETDKREFEKAVETIAVSFSSTVSEFLMGEVDSSTILSIPPSDQNQSMESLYGGIPGPGGDGVPSGMESYDTVRPAAEEVDVMLQRCEGGVDAALQYAKNISKYMKDLIGYLEKRTALEMEFAKGLQKMANSCKQTFTQETSMPFLSIYLLALEQDMEYGMSVLQTVTTLQHQTFLQPLTVRRLEHEKRRKEIKEQWHRAQRKLQDAEVNLRKAKQVYMQRSEEHDKAKYVTVKAEEEQQSTASSITTKTLDKKRRLEEEAKNKAEEAMATYRTCVADANTQKQELEDTKVNSLRQIHELIKQSDQVIKLATIAFYQIMHMQTAPLPVYFQTLCESSKLYDPGQQYASHVKQLQRGDEPDTQYDFEPYVSHSAWSPFTRARKGSFNASDFSSSGGSDGAGLPRDGSSTEGPRETQGGTLAERRGRGHQVHKSWPTSTSEADSSLDSSTAGEFGHKLQRLSSNGTMSSSEELGEKDENATSFEQSINGITPEMTAPTGPFRNVGLSRAAQTHRLRKLRAPSKCRECNSYVYFQGAECEECYLACHKKCLETLAIQCGHKKLQGKLQLFGQDFLKASQGSADGIPFIVKKCISEIEKRALKTKGIYRVNGVKTRVEKLCQAFENGKELVELSQASPHDISNVLKLYLRQLPEPIVPFRMYNALMGAAKESLQGGSDAKGRSGKGGPELMDRGADTDRGPSWLFGCMFELQNLCCDGSRGRCRTPEPSYSPPPP", "length": 924, "header": "tr|A0A8V1AEC7-1|A0A8V1AEC7_CHICK Computationally mapped isoform of Rho GTPase activating protein 45 OS=Gallus gallus OX=9031 GN=ARHGAP45 PE=1 SV=1 CANONICAL=A0A8V1ABJ6-1" }, "locus": { "chromosome": "28", "start_pos": 3366688, "end_pos": 3355553, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067848.1", "url": "https://www.ensembl.org/id/ENSGALT00010067848.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041591.1", "url": "https://www.ensembl.org/id/ENSGALP00010041591.1" } ] } }, { "isoform_ac": "A0A8V1AED7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABJ6/entry#A0A8V1AED7-1", "sequence": { "sequence": "MFSRKKRELMKTPSISKKSRAGSPIPQTLPDLSRKDCLEAPSPGELPPTSVKLSSSPSAVGTLKRPTSLSRHASAAGFPLTSAGPRAVPKGHKTPTSYSPMEGGEGLFIDVEDISQLLTDVARFADALENLRDVVLRDDPKESQRPQAHECLGETLRVLRQVINKYPLLNTLETLTAAGTLISKVKGFHYESNNETDKREFEKAVETIAVSFSSTVSEFLMGEVDSSTILSIPPSDQNQSMESLYGGIPGPGGDGVPSGMESYDTVRPAAEEVDVMLQRCEGGVDAALQYAKNISKYMKDLIGYLEKRTALEMEFAKGLQKMANSCKQTFTQETSMPFLSIYLLALEQDMEYGMSVLQTVTTLQHQTFLQPLTVRRLEHEKRRKEIKEQWHRAQRKLQDAEVNLRKAKQVYMQRSEEHDKAKYVTVKAEEEQQSTASSITTKTLDKKRRLEEEAKNKAEEAMATYRTCVADANTQKQELEDTKVNSLRQIHELIKQSDQVIKLATIAFYQIMHMQTAPLPVYFQTLCESSKLYDPGQQYASHVKQLQRGDEPDTQYDFEPYVSHSAWSPFTRARKGSFNASDFSSSGGSDGAGLPRDGSSTEGPRETQGGTLAERRAGRGHQVHKSWPTSTSEADSSLDSSTGINGITPEMTAPTGPFRNVGLSRAAQTHRLRKLRAPSKCRECNSYVYFQGAECEECYLACHKKCLETLAIQCGHKKLQGKLQLFGQDFLKASQGSADGIPFIVKKCISEIEKRALKTKGIYRVNGVKTRVEKLCQAFENGKELVELSQASPHDISNVLKLYLRQLPEPIVPFRMYNALMGAAKESLQGGSDAKGRSGKGGPELMDRGADTDRVVVNLVLKLKELLKELPWENTATLRYLLQHLRRIVEVEQDNKMTSSNLGIVFGPTLLRPRPTDATISLSSLVDYPHQARVIEALIIFYPTIFEDKDSKLTAEGSEFSADREEDTPDEPTAAPCPQPPGKGDLGYSVGAFGEPSERSVDSDSELEDGGEPAGSGQLRKQESETSTDEAPFYEEGSEGQRSRTCSTGQSDTEGAALRCAAGEHSDPEEDPESSAAQQ", "length": 1079, "header": "tr|A0A8V1AED7-1|A0A8V1AED7_CHICK Computationally mapped isoform of Rho GTPase activating protein 45 OS=Gallus gallus OX=9031 GN=ARHGAP45 PE=1 SV=1 CANONICAL=A0A8V1ABJ6-1" }, "locus": { "chromosome": "28", "start_pos": 3366449, "end_pos": 3355553, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067858.1", "url": "https://www.ensembl.org/id/ENSGALT00010067858.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041601.1", "url": "https://www.ensembl.org/id/ENSGALP00010041601.1" } ] } }, { "isoform_ac": "A0A8V1AGW5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABJ6/entry#A0A8V1AGW5-1", "sequence": { "sequence": "MFSRKKRELMKTPSISKKSRAGSPIPQTLPDLSRKDCLEAPSPGELPPTSVKLSSSPSAVGTLKRPTSLSRHASAAGFPLTSAGPRAVPKGHKTPTSYSPMEGGEGLFIDVEDISQLLTDVARFADALENLRDVVLRDDPKESQRPQAHECLGETLRVLRQVINKYPLLNTLETLTAAGTLISKVKGFHYESNNETDKREFEKAVETIAVSFSSTVSEFLMGEVDSSTILSIPPSDQNQSMESLYGGIPGPGGDGVPSGMESYDTVRPAAEEVDVMLQRCEGGVDAALQYAKNISKYMKDLIGYLEKRTALEMEFAKGLQKMANSCKQTFTQETSMPFLSIYLLALEQDMEYGMSVLQTVTTLQHQTFLQPLTVRRLEHEKRRKEIKEQWHRAQRKLQDAEVNLRKAKQVYMQRSEEHDKAKYVTVKAEEEQQSTASSITTKTLDKKRRLEEEAKNKAEEAMATYRTCVADANTQKQELEDTKVNSLRQIHELIKQSDQVIKLATIAFYQIMHMQTAPLPVYFQTLCESSKLYDPGQQYASHVKQLQRGDEPDTQYDFEPYVSHSAWSPFTRARKGSFNASDFSSSGGSDGAGLPRDGSSTEGPRETQGGTLAERRAGRGHQVHKSWPTSTSEADSSLDSSTAGEFGHKLQRLSSNGTMSSSEELGEKDENATSFEQSINGITPEMTAPTGPFRNVGLSRAAQTHRLRKLRAPSKCRECNSYVYFQGAECEECYLACHKKCLETLAIQCGHKKLQGKLQLFGQDFLKASQGSADGIPFIVKKCISEIEKRALKTKGIYRVNGVKTRVEKLCQAFENGKELVELSQASPHDISNVLKLYLRQLPEPIVPFRMYNALMGAAKESLQGGSDAKGRSGKGGPELMDRGADTDRVVVNLVLKLKELLKELPWENTATLRYLLQHLRRIVEVEQDNKMTSSNLGIVFGPTLLRPRPTDATISLSSLVDYPHQARVIEALIIFYPTIFEDKDSKLTAEGSEFSADREEDTPDEPTAAPCPQPPGKGDLGYSVGAFGEPSERSVDSDSELEDGGEPAGSGQLRKQESETSTDEAPFYEEGSEGQRSRTCSTGQSDTEGAALRCAAGEHSDPEEDPESSAAQQ", "length": 1114, "header": "tr|A0A8V1AGW5-1|A0A8V1ABJ6_CHICK Computationally mapped isoform of Rho GTPase activating protein 45 OS=Gallus gallus OX=9031 GN=ARHGAP45 PE=1 SV=1 CANONICAL=A0A8V1ABJ6-1" }, "locus": { "chromosome": "28", "start_pos": 3366449, "end_pos": 3355553, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067857.1", "url": "https://www.ensembl.org/id/ENSGALT00010067857.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041600.1", "url": "https://www.ensembl.org/id/ENSGALP00010041600.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1021, "start_aa": "Thr", "end_pos": 1021, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1021", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-GGA-6798695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798695", "resource": "Reactome", "description": "Neutrophil degranulation" }, { "id": "R-GGA-8980692", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8980692", "resource": "Reactome", "description": "RHOA GTPase cycle" }, { "id": "R-GGA-9013148", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013148", "resource": "Reactome", "description": "CDC42 GTPase cycle" }, { "id": "R-GGA-9013149", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013149", "resource": "Reactome", "description": "RAC1 GTPase cycle" } ], "orthologs": [ { "uniprot_canonical_ac": "A0ABK0L8V3-1", "protein_name": "Rho GTPase activating protein 45", "gene_name": "Arhgap45", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRSGFWNVPDCVEDPGTFLVQPEAHPRASQSSNRHNLSNPLPSQPTMSGRRGPLKELLGWVCGWTRAWRTRLGTTGCGLSGLCPGEPPSVSEELPRKDCTETPSLEPPAMSLSTVAKGTGTLKRPTSLSRHASAAGFPLSGTATRTLGRGYRSPLSAASPAELPTEGPFPDGVEDISTLLADVARFAEGLEKLKEFVLRDDLLEARRPLAHECLGEALRVMRQVISKYPLLNTVETLTAAGTLIAKVKAFHYECNNESDKREFEKALETIAVSFSCTVSEFLLGEVDSSTLLAVPPGDPSQLVENLYGSGSEGPPHSVEDCEEGCLPPEEVDMLLQRCEGGVDAALQYAKDMARYMKDLIGYLEKRTTLEMEFAKGLQKVVHNCRQNVTHAPHMPLLSIYSLALEQDLEFGHGMVQAVGTLQTQTFMQPLTLRRLEHERRRKEIKESWHRAQRKLQEAEANLRKAKQGYKQRCEDHDKARLQVAKAEEEQQGTGPGAGTAASKALDKRRRLEEEAKNKAEEAMATYRTCVADAKTQKQELEDTKVTALRQIQEVIRQSDQTIKSATISYYQLMHMQTAPLPVNFQMLCESSKLYDPGQQYASHVRQLQRGEEPDVRYDFEPYVSTNAWSPIMRTRKGSFNPGDASGPEAAGSPPEEGGTSEGAPNKDHRGGRGHQVHKSWPISISDTEVSLDVSSGDLKKFDRTSSSGTMSSNEELVDQEAGLVASAFDSADLNGMDPELPVAMPSGPFRHVGLSKAARTHRLRKLRTPAKCRECNSYVYFQGAECEECCLACHKKCLETLAIQCGHKKLQGRLQLFGQDFSQAAHSTPDGVPFIIKKCVCEIERRALHTKGIYRVNGVKTRVEKLCQAFENGKELVELSQASPHDISNVLKLYLRQLPEPLISFRFYHELVGLAKDSLKAEAEAKAASRGRQDGSESEAATLAMVGRLRELMRDLPAENRATLLYLLRHLRRIVEMEQDNKMTPGNLGIVFGPTLLRPRPTDATVSLSSLVDYPHQARVIETLIVHYGLVFEEEPEEAAGSQEGASAQCAQLETAEGIVFPQQEEADDGNRESQVASNDSDSELEEASDLLSSSDASALHRLSFLEQTEAGLEEGPQSHSGSEEQLESEDAAPGHQLCSFNTNQSNNTTQASLPTMRLRDGQITGGSGRKRQPQFV", "length": 1177 }, "evidence": [ { "id": "A0A8V1ABJ6", "url": "https://omabrowser.org/oma/group/A0A8V1ABJ6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q3TBD2-1", "protein_name": "Rho GTPase-activating protein 45", "gene_name": "Arhgap45", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSRKKRELMKTPSISKKNRAGSPNPQSSSGELPRKDWTEAPGLEPPATSLSTVAKGTGTLKRPTSLSRHASAAGFPLSGTATWTLVRGYRSPLSAASPAELPTEGAFPDGVEDISTLLADVARFAEGLEKLKECVLQDDLLEARRPLAHECLGEALRVMRQVISRYPLLNTVETLTAAGTLIAKVKAFHYECNNESDKREFEKALETIAVSFSCTVSEFLLGEVDSSTLLAVPPGDPSQSMENLYGAGTEGPPHNVEECEEGCLPPEEVDMLLQRCEGGVDAALQYAKDMARYMKDLISYLEKRTTLEMEFAKGLQKVVHNCRQSVTHEPHMPLLSIYSLALEQDLEFGHGMVQAAGTLQTQTFMQPLTLRRLEHERRRKEIKESWHRAQRKLQEAEANLRKAKQGYKQRCEDHDKARLQVAKAEEEQQGTGPGAGTAASKALDKRRRLEEEAKNKAEEAMATYRTCVADAKTQKQELEDTKVTALRQIQEVIRQSDQTIKSATISYYQLMHMQTAPLPVNFQMLCESSKLYDPGQQYASHVRQLQRGEEPDVRYDFEPYVSNNSWSPIMRTRKGSFNPGDASGPEAAGSPPEEGGTSEAAPNKDHRGGRGHQVHKSWPISISDTEVGLDTSSGDLKKFDRTSSSGTMSSSEELGDQEAGLVASAFDSADLNGMDPELPVAMPSGPFRHVGLSKAARTHRLRKLRTPAKCRECNSYVYFQGAECEECCLACHKKCLETLAIQCGHKKLQGRLQLFGQDFSQAALSTPDGVPFIVKKCVCEIERRALHTKGIYRVNGVKTRVEKLCQAFENGKELVELSQASPHDISNVLKLYLRQLPEPLISFRFYHELVGLAKDSLKAEAEAKAASRGRQGGSESEAATLAMVGRLRELMQDLPAENRATLLYLLKHLRRIVEMEQDNKMTPGNLGIVFGPTLLRPRPTDATVSLSSLVDYPHQARVIETLIVHYGLVFEEEPEEAPGSQEGASTQCGQLESAEGIVFPLQEEAEDGSRESHAASNDSDSELEDASDPLSSSDASALHRLSFLEQTEAGLEEGPQSHSGSEEQLEGEDGAPGPWLCHFNTNQSNNTSRAPLPTMRLRGGQITGGTSQERQPQFV", "length": 1116 }, "evidence": [ { "id": "A0A8V1ABJ6", "url": "https://omabrowser.org/oma/group/A0A8V1ABJ6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q92619-1", "protein_name": "Rho GTPase-activating protein 45", "gene_name": "ARHGAP45", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MFSRKKRELMKTPSISKKNRAGSPSPQPSGELPRKDGADAVFPGPSLEPPAGSSGVKATGTLKRPTSLSRHASAAGFPLSGAASWTLGRSHRSPLTAASPGELPTEGAGPDVVEDISHLLADVARFAEGLEKLKECVLRDDLLEARRPRAHECLGEALRVMHQIISKYPLLNTVETLTAAGTLIAKVKAFHYESNNDLEKQEFEKALETIAVAFSSTVSEFLMGEVDSSTLLAVPPGDSSQSMESLYGPGSEGTPPSLEDCDAGCLPAEEVDVLLQRCEGGVDAALLYAKNMAKYMKDLISYLEKRTTLEMEFAKGLQKIAHNCRQSVMQEPHMPLLSIYSLALEQDLEFGHSMVQAVGTLQTQTFMQPLTLRRLEHEKRRKEIKEAWHRAQRKLQEAESNLRKAKQGYVQRCEDHDKARFLVAKAEEEQAGSAPGAGSTATKTLDKRRRLEEEAKNKAEEAMATYRTCVADAKTQKQELEDTKVTALRQIQEVIRQSDQTIKSATISYYQMMHMQTAPLPVHFQMLCESSKLYDPGQQYASHVRQLQRDQEPDVHYDFEPHVSANAWSPVMRARKSSFNVSDVARPEAAGSPPEEGGCTEGTPAKDHRAGRGHQVHKSWPLSISDSDSGLDPGPGAGDFKKFERTSSSGTMSSTEELVDPDGGAGASAFEQADLNGMTPELPVAVPSGPFRHEGLSKAARTHRLRKLRTPAKCRECNSYVYFQGAECEECCLACHKKCLETLAIQCGHKKLQGRLQLFGQDFSHAARSAPDGVPFIVKKCVCEIERRALRTKGIYRVNGVKTRVEKLCQAFENGKELVELSQASPHDISNVLKLYLRQLPEPLISFRLYHELVGLAKDSLKAEAEAKAASRGRQDGSESEAVAVALAGRLRELLRDLPPENRASLQYLLRHLRRIVEVEQDNKMTPGNLGIVFGPTLLRPRPTEATVSLSSLVDYPHQARVIETLIVHYGLVFEEEPEETPGGQDESSNQRAEVVVQVPYLEAGEAVVYPLQEAAADGCRESRVVSNDSDSDLEEASELLSSSEASALGHLSFLEQQQSEASLEVASGSHSGSEEQLEATAREDGDGDEDGPAQQLSGFNTNQSNNVLQAPLPPMRLRGGRMTLGSCRERQPEFV", "length": 1136 }, "evidence": [ { "id": "A0A8V1ABJ6", "url": "https://omabrowser.org/oma/group/A0A8V1ABJ6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABJ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABJ6" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABJ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABJ6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABJ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABJ6" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABJ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABJ6" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABJ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABJ6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABJ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABJ6" } ], "pmid": "" }, { "name": "negative regulation of small GTPase mediated signal transduction", "id": "GO:0051058", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051058", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABJ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABJ6" } ], "pmid": "" }, { "name": "regulation of small GTPase mediated signal transduction", "id": "GO:0051056", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051056", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABJ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABJ6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 207, "end_pos": 209, "annotation": "n_glycosylation_sequon" }, { "start_pos": 251, "end_pos": 253, "annotation": "n_glycosylation_sequon" }, { "start_pos": 306, "end_pos": 308, "annotation": "n_glycosylation_sequon" }, { "start_pos": 592, "end_pos": 594, "annotation": "n_glycosylation_sequon" }, { "start_pos": 669, "end_pos": 671, "annotation": "n_glycosylation_sequon" }, { "start_pos": 684, "end_pos": 686, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1ABJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABJ6" }, { "id": "PS51741", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51741" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "F-BAR", "eco_id": "ECO_0000259", "start_pos": 284, "end_pos": 551, "start_aa": "Glu", "end_aa": "Gln", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1ABJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABJ6" }, { "id": "PS50081", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50081" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Phorbol-ester/DAG-type", "eco_id": "ECO_0000259", "start_pos": 717, "end_pos": 762, "start_aa": "Thr", "end_aa": "Cys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1ABJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABJ6" }, { "id": "PS50238", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50238" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Rho-GAP", "eco_id": "ECO_0000259", "start_pos": 776, "end_pos": 994, "start_aa": "Gln", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 1021 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 207, "end_pos": 209 }, { "start_pos": 251, "end_pos": 253 }, { "start_pos": 306, "end_pos": 308 }, { "start_pos": 592, "end_pos": 594 }, { "start_pos": 669, "end_pos": 671 }, { "start_pos": 684, "end_pos": 686 } ] }, "class_list": [], 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##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. 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{ "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1ABL7-1", "uniprot_ac": "A0A8V1ABL7", "uniprot_id": "A0A8V1ABL7_CHICK", "mass": { "chemical_mass": 34277.0, "monoisotopic_mass": 34277.0 }, "refseq": { "ac": "XP_004939127", "name": "vesicle-trafficking protein SEC22c", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004939127" }, "gene_names": [ { "name": "SEC22C", "type": "recommended", "evidence": [ { "id": "A0A8V1ABL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABL7" } ] }, { "name": "SEC22C", "type": "synonym", "evidence": [ { "id": "XP_004939127", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004939127" } ] } ], "protein_names": [ { "name": "SEC22 homolog C, vesicle trafficking protein", "type": "synonym", "evidence": [ { "id": "A0A8V1ABL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABL7/entry#names_and_taxonomy" } ] }, { "name": "vesicle-trafficking protein SEC22c", "type": "synonym", "evidence": [ { "id": "XP_004939127", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004939127" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052533.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004939127.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004939127", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004939127" } ] }, { "annotation": "May be involved in vesicle transport between the ER and the Golgi complex.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGC0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGC0#function" }, { "database": "UniProtKB", "id": "ARBA00003595", "url": "https://www.uniprot.org/uniprotkb/ARBA00003595#function" }, { "database": "UniProtKB", "id": "A0A8V1ABL7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABL7#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABL7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABL7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SEC22C", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABL7", "locus": { "chromosome": "2", "start_pos": 1928001, "end_pos": 1947250, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027367", "url": "https://www.ensembl.org/id/ENSGALG00010027367" } ] } } ], "crossref": [ { "id": "A0A8V1ABL7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1ABL7", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd14824", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14824", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "420387", "url": "https://www.ncbi.nlm.nih.gov/gene/420387", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR010908", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010908", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011012", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011012", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043546", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043546", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR059071", "url": "https://www.ebi.ac.uk/interpro/entry/IPR059071", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:420387", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420387", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QDRTNDC", "url": "https://omabrowser.org/oma/group/QDRTNDC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ABL7", "url": "https://www.orthodb.org/?gene=A0A8V1ABL7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AGC0", "url": "https://www.orthodb.org/?gene=A0A8V1AGC0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46258", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46258", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46258:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46258:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13774", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13774", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25970", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25970", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-204005", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-204005", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_004939127", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004939127", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1ABL7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABL7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ABL7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABL7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGC0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGC0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGC0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGC0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSMIFFACVVRVRDGLPLSASTDFHFNQDFLECRKKLKALSSVLARYPSRGTAKGRDLSIHFLSSGEIACMAICSSSYSTIMAFCFLEELQWAFAASYDTTSINLASRPYAFLEFDNAIQKVKHRFNYMSGSATKVSWEKVEEELRLQPPVQLKLEDAELMNGMANGGHAGVHVEVAPAYRMQRVTPLGILSLVLNIMCGALNLIRGVHLAEHSFQEDYEGIGNVVAFFLPFLACVFQCYLYLYYSSTRKVKTFVLFFSVCLCNIYLYGLRNLWQIAFHIGVASLSSYQILTRQLMEKQPDCGV", "length": 304, "header": "tr|A0A8V1ABL7-1|A0A8V1ABL7_CHICK Isoform 1 of SEC22 homolog C, vesicle trafficking protein OS=Gallus gallus OX=9031 GN=SEC22C PE=3 SV=1 CANONICAL=A0A8V1ABL7-1" }, "isoforms": [ { "isoform_ac": "A0A8V1ABL7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABL7/entry#A0A8V1ABL7-1", "sequence": { "sequence": "MSMIFFACVVRVRDGLPLSASTDFHFNQDFLECRKKLKALSSVLARYPSRGTAKGRDLSIHFLSSGEIACMAICSSSYSTIMAFCFLEELQWAFAASYDTTSINLASRPYAFLEFDNAIQKVKHRFNYMSGSATKVSWEKVEEELRLQPPVQLKLEDAELMNGMANGGHAGVHVEVAPAYRMQRVTPLGILSLVLNIMCGALNLIRGVHLAEHSFQEDYEGIGNVVAFFLPFLACVFQCYLYLYYSSTRKVKTFVLFFSVCLCNIYLYGLRNLWQIAFHIGVASLSSYQILTRQLMEKQPDCGV", "length": 304, "header": "tr|A0A8V1ABL7-1|A0A8V1ABL7_CHICK Isoform 1 of SEC22 homolog C, vesicle trafficking protein OS=Gallus gallus OX=9031 GN=SEC22C PE=3 SV=1 CANONICAL=A0A8V1ABL7-1" }, "locus": { "chromosome": "2", "start_pos": 1941760, "end_pos": 1931550, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066354.1", "url": "https://www.ensembl.org/id/ENSGALT00010066354.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040620.1", "url": "https://www.ensembl.org/id/ENSGALP00010040620.1" } ] } }, { "isoform_ac": "A0A8V1AGC0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABL7/entry#A0A8V1AGC0-1", "sequence": { "sequence": "MVCVWIVTSYLSLETEFHSARAVQLLLSFVSICFLSSGEIACMAICSSSYSTIMAFCFLEELQWAFAASYDTTSINLASRPYAFLEFDNAIQKVKHRFNYMSGSATKVSWEKVEEELRLQPPVQLKLEDAELMNGMANGGHAGVHVEVAPAYRMQRVTPLGILSLVLNIMCGALNLIRGVHLAEHSFQEDYEGIGNVVAFFLPFLACVFQCYLYLYYSSTRKVKTFVLFFSVCLCNIYLYGLRNLWQIAFHIGVASLSSYQILTRQLMEKQPDCGV", "length": 276, "header": "tr|A0A8V1AGC0-1|A0A8V1ABL7_CHICK Computationally mapped isoform of SEC22 homolog C, vesicle trafficking protein OS=Gallus gallus OX=9031 GN=SEC22C PE=3 SV=1 CANONICAL=A0A8V1ABL7-1" }, "locus": { "chromosome": "2", "start_pos": 1941473, "end_pos": 1931550, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066351.1", "url": "https://www.ensembl.org/id/ENSGALT00010066351.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040617.1", "url": "https://www.ensembl.org/id/ENSGALP00010040617.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:420387", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420387", "resource": "KEGG Pathway" }, { "id": "R-GGA-204005", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-204005", "resource": "Reactome", "description": "COPII-mediated vesicle transport" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287AJP5-1", "protein_name": "Vesicle-trafficking protein SEC22c", "gene_name": "SEC22C", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSMILFACVVRVRDGLPLSASTDFYHTQDFLECRRRLKTLALRLAQYPGRGSAKGRDFSIHFSSSRDVACMAICSHQCPSAMAFYFLETLWWEFTASYDTTCIGLASRPYAFLEFDSVIQKVKWHFNYVSSTQMENSLEKIQEDLKFQPPVVLTLEDTDVANGVMNGHTRMHLEPAPNFRMEPVTALGVLSLILNIMCAALNLIRGIHLAEHSLQVAHEEIGNILAFLIPFVACIFQCYLYLFYSPARTMKVVLMLLFICLGNMYLHGLRNLWQILFHIGVAFLSSHQILTRQLQEKQSDCGV", "length": 303 }, "evidence": [ { "id": "A0A8V1ABL7", "url": "https://omabrowser.org/oma/group/A0A8V1ABL7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A9J7FXZ0-1", "protein_name": "Vesicle-trafficking protein SEC22c isoform X1", "gene_name": "Sec22c", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MPMILFASVVRVRDGLPLSASTDFYHAQEFLECRRQLKALARRLPQYPGRGSAESRDFNIYFSSSGGVACMAICSRQCPAAMVFCFLETLWWDFTASYDTTCIGLASRPYAFLEFDSVIQKTKWRFNHMSSSQMKSGLEKIQEELELQPPAMLSIEGTDVANGMLNGHTPVHSEPAPNLRMEPVTALGVLSLVLNILCAALNLVRGVHLAEHSLQVAQEEVGNILAFFIPSVACIVQSSQDSEGGADSGLHLPGQHVPARAEEHLASPLSHRSGFSVLVSDPDQTAAGEAVRLWSVRTASRSERSL", "length": 306 }, "evidence": [ { "id": "A0A8V1ABL7", "url": "https://omabrowser.org/oma/group/A0A8V1ABL7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "E9QFN4-1", "protein_name": "Vesicle-trafficking protein SEC22c isoform X1", "gene_name": "sec22c", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSLILFAFVVRVRDGLPLSASTDFLHNKELQEKKQQIKIISKSLNVLPERGTVKGHELNIHFLSCEGVSYMSVCACTLPAATAFCFLEDLRWEFTACFDNSAVAMANRPYPFLEFDSAIQKLQQHYNQKGGPSLEVTLAEVQEDLRSSPPQVLTMEDVVLSNGAANGHVEQTTASGQSQRLEPVSAPGILSLVLNIMCAALNLIRGVHLIEYTFQDDYDGLWNVVAFLVAFLCCVCQCHLYLFHTCQKRLKSFTLLTLIVLCNAFLFGPRNIWQLVFHLSVACLSTLLTLHRKLQDRNTDCGV", "length": 303 }, "evidence": [ { "id": "A0A8V1ABL7", "url": "https://omabrowser.org/oma/group/A0A8V1ABL7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q2YDJ2-1", "protein_name": "Vesicle-trafficking protein SEC22c", "gene_name": "SEC22C", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSLILFACVVRVRDGLPLSASTDFYHSQDFLECRRRLKTLALRLAQYPGRGSAEGCDFSIHFSSSRDVACMAICSLQCPAAMAFCFLETLWWEFTASYDTTCVGLASRPYAFLEFDNVIQKVKWHFNYVSSTQMDSSLGKIQEELKFQPPVVLTLEDTDVANGVMNGHTLMHLEPAPSFRMEPVTALGILSLILNIMCAALNLIRGIHLAEHSLQVAHEEIGNILAFLIPFVACIFQCYLYLFYSPARTMKVVLMLLFICLGNVYLHGLRNLWQILFHIGVAFLSSHQILTRQLQDKQSDCGV", "length": 303 }, "evidence": [ { "id": "A0A8V1ABL7", "url": "https://omabrowser.org/oma/group/A0A8V1ABL7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8BXT9-1", "protein_name": "Vesicle-trafficking protein SEC22c", "gene_name": "Sec22c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSMILFASIVRVRDGLPLSASTDFYYAQEFLECRRQLKTLAQRLARHPGRGCAESCDFLIYFSSSGDVACMAICSRQCPAAMAFCFLEALWWDFIASYDTTCVGLASRPYAFLEFDSVIQKTKWHFNHMSSSQMKSGLEKIQEELEFQPPAVLSLEDTDVANGMLNGHTPVHSEPAPNLRMKPVTALGVLSLVLNIMCAALNLIRGVHLAEHSLQVAQEEVGNILAFFIPSVACIVQCYLYLFYSPARTLKVLLMLASICLGNAYLHGLRNTWQILFHVGVAFLSSYQILTRQLQERQSDYGV", "length": 303 }, "evidence": [ { "id": "A0A8V1ABL7", "url": "https://omabrowser.org/oma/group/A0A8V1ABL7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9BRL7-1", "protein_name": "Vesicle-trafficking protein SEC22c", "gene_name": "SEC22C", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSVIFFACVVRVRDGLPLSASTDFYHTQDFLEWRRRLKSLALRLAQYPGRGSAEGCDFSIHFSSFGDVACMAICSCQCPAAMAFCFLETLWWEFTASYDTTCIGLASRPYAFLEFDSIIQKVKWHFNYVSSSQMECSLEKIQEELKLQPPAVLTLEDTDVANGVMNGHTPMHLEPAPNFRMEPVTALGILSLILNIMCAALNLIRGVHLAEHSLQVAHEEIGNILAFLVPFVACIFQCYLYLFYSPARTMKVVLMLLFICLGNMYLHGLRNLWQILFHIGVAFLSSYQILTRQLQEKQSDCGV", "length": 303 }, "evidence": [ { "id": "A0A8V1ABL7", "url": "https://omabrowser.org/oma/group/A0A8V1ABL7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABL7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABL7" } ], "pmid": "" }, { "name": "endoplasmic reticulum to Golgi vesicle-mediated transport", "id": "GO:0006888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006888", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABL7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABL7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABL7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABL7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1ABL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABL7" }, { "id": "PS50859", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50859" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Longin", "eco_id": "ECO_0000259", "start_pos": 8, "end_pos": 119, "start_aa": "Cys", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } 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"tr|A0A8V1ABM6-1|A0A8V1ABM6_CHICK Isoform 1 of Coiled-coil domain containing 92B OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1ABM6-1" }, "locus": { "chromosome": "19", "start_pos": 9996341, "end_pos": 9989148, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070697.1", "url": "https://www.ensembl.org/id/ENSGALT00010070697.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043388.1", "url": "https://www.ensembl.org/id/ENSGALP00010043388.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 50, "start_aa": "Thr", "end_pos": 50, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr50", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": 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"Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 50 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 39, "end_pos": 41 }, { "start_pos": 53, "end_pos": 55 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", 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"uniprot_ac": "A0A8V1ABN0", "uniprot_id": "A0A8V1ABN0_CHICK", "mass": { "chemical_mass": 53243.0, "monoisotopic_mass": 53243.0 }, "refseq": { "ac": "NP_001025859", "name": "ankyrin repeat and SOCS box protein 6", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025859" }, "gene_names": [ { "name": "ASB6", "type": "recommended", "evidence": [ { "id": "A0A8V1ABN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABN0" } ] }, { "name": "ASB6", "type": "synonym", "evidence": [ { "id": "NP_001025859", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025859" } ] } ], "protein_names": [ { "name": "Ankyrin repeat and SOCS box containing 6", "type": "synonym", "evidence": [ { "id": "A0A8V1ABN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABN0/entry#names_and_taxonomy" } ] }, { "name": "ankyrin repeat and SOCS box protein 6", "type": "synonym", "evidence": [ { "id": "NP_001025859", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025859" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ851562.1, SRR13267648.14088.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN05341171 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000308.1. On Oct 25, 2021 this sequence version replaced NP_001025859.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001025859", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025859" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABN0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABN0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ASB6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABN0", "locus": { "chromosome": "17", "start_pos": 6249139, "end_pos": 6254129, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028010", "url": "https://www.ensembl.org/id/ENSGALG00010028010" } ] } } ], "crossref": [ { "id": "A0A8V1ABN0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1ABN0", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd03725", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03725", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "417194", "url": "https://www.ncbi.nlm.nih.gov/gene/417194", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001496", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001496", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036036", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036036", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037327", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037327", "database": 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"PF07525", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07525", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13637", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13637", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-8951664", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8951664", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-983168", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983168", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001025859", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025859", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1ABN0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABN0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ABN0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABN0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MREGPAGPVCRAQRSRMPFLHGFRRITLEYQPLVDEILALLALQDAERQDTLESHACLGSNGSQLSAMRQVLEREAHSPFYQEGVSYTLLKVTELGLVEAAEVLLEFGAHLSFEDPVTYYTPLHIAVLRNQPDMVELLARHGADINRRDRIHESSPLDLASEEPERLPCLQRLLQLGADVNAADKTGKTALLHALLHCYCSSDVVQIHNTESIRLLLEGGADARATTEDGDTVFTYIIFLLGDIVLASTEEAEVQNRFCIRVMQLLMAHGANPSECPSLESFTYRCLQNFTCHFPLLRFLLESGAAYNCSLHGPSCWSGFQTVFDCLCSHVSILKDSSISTEVIQMGQTLLELMMASSQTIQLPSDFEVDVNSCRYHEEKIRTLFCSVKQLEHTPQALKHLCRVFIRQRLRPWPIDIKIKALPLPDRLKWYLLIDHAAVGHEDLSLTDDSPSPHSVVTVPPDSQQITALHPLSLQ", "length": 475, "header": "tr|A0A8V1ABN0-1|A0A8V1ABN0_CHICK Isoform 1 of Ankyrin repeat and SOCS box containing 6 OS=Gallus gallus OX=9031 GN=ASB6 PE=4 SV=1 CANONICAL=A0A8V1ABN0-1" }, "isoforms": [ { "isoform_ac": "A0A8V1ABN0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABN0/entry#A0A8V1ABN0-1", "sequence": { "sequence": "MREGPAGPVCRAQRSRMPFLHGFRRITLEYQPLVDEILALLALQDAERQDTLESHACLGSNGSQLSAMRQVLEREAHSPFYQEGVSYTLLKVTELGLVEAAEVLLEFGAHLSFEDPVTYYTPLHIAVLRNQPDMVELLARHGADINRRDRIHESSPLDLASEEPERLPCLQRLLQLGADVNAADKTGKTALLHALLHCYCSSDVVQIHNTESIRLLLEGGADARATTEDGDTVFTYIIFLLGDIVLASTEEAEVQNRFCIRVMQLLMAHGANPSECPSLESFTYRCLQNFTCHFPLLRFLLESGAAYNCSLHGPSCWSGFQTVFDCLCSHVSILKDSSISTEVIQMGQTLLELMMASSQTIQLPSDFEVDVNSCRYHEEKIRTLFCSVKQLEHTPQALKHLCRVFIRQRLRPWPIDIKIKALPLPDRLKWYLLIDHAAVGHEDLSLTDDSPSPHSVVTVPPDSQQITALHPLSLQ", "length": 475, "header": "tr|A0A8V1ABN0-1|A0A8V1ABN0_CHICK Isoform 1 of Ankyrin repeat and SOCS box containing 6 OS=Gallus gallus OX=9031 GN=ASB6 PE=4 SV=1 CANONICAL=A0A8V1ABN0-1" }, "locus": { "chromosome": "17", "start_pos": 6253851, "end_pos": 6250385, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067891.1", "url": "https://www.ensembl.org/id/ENSGALT00010067891.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041634.1", "url": "https://www.ensembl.org/id/ENSGALP00010041634.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:417194", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417194", "resource": "KEGG Pathway" }, { "id": "R-GGA-8951664", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8951664", "resource": "Reactome", "description": "Neddylation" }, { "id": "R-GGA-983168", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983168", "resource": "Reactome", "description": "Antigen processing: Ubiquitination & Proteasome degradation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6ANG1-1", "protein_name": "Ankyrin repeat and SOCS box-containing 6", "gene_name": "Asb6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPFLHGFRRIIFEYQPLVDAILGALGIQDLERQEPLDDYASSEESRILVLTELLEQKAHSPFYQEGVSNALLKMAELGLTRAAAVLLQSGANLNFEDPVTYYTALHIAVLRNQPDMVELLVRHGADINRRDRIHESSPLDLASEEPERLPCLQRLLDLGADVNAADKNGADVKATTKDGDTVFTCIIFLLGETVCGDKEEAPMINRFCFQVTQLLLAHGADPSECPAHESLTHICLKSFKLHFPLLRFLLESGAAYNCSLHGASCWSGFNLIFERLCSHPGCAEDDSHVELLHKAETVLDLMVTSSQRLQLPENFNIHPVGGLAGKIQALHASLRQLESYPPPLKHLCRVSIRLCLRPWPVDTKVKALPLPDRLKWYLLSAHSSPEDTC", "length": 389 }, "evidence": [ { "id": "A0A8V1ABN0", "url": "https://omabrowser.org/oma/group/A0A8V1ABN0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8M2BE57-1", "protein_name": "Ankyrin repeat and SOCS box protein 6 isoform X1", "gene_name": "asb6", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MPFLHGFRRIVYEYQPLVDAVLCVLGTDGENQRRQDEEESVSVALAELLDREAQSPVFMQGISYSLFRVAEFGLVSAAQVLLRYGADLNFEDPVSYYNPLHIAVLRNKPDMVRMLISSGADIDKRDRIHESSPIDLASEEADKLPCLRVLLDFGADVNAKDKNGKTALLHALASSDGLTVKNMDNIQLLLERGADVNATTQDGETPMSSLAFLVKEALESSVEDAKEIGHFCTHVAHLLISHGAGPSCCLSATDGEVWEHSLTYTSLENFDLLFPLTVLLLQHSASFVCSHHSASYWTGPQLIFTRLAEALREAVDAAEVADVLAKAEVLLDLARICSPAIPPLFPRSQLPVLEQGSIHEPLLELYGKLEERESQPMPLRCLCRRLIRNCLLPWPFEEKVKALPLPDRLKDLLLPENSWKNRAGWDRFKPRGSSH", "length": 435 }, "evidence": [ { "id": "A0A8V1ABN0", "url": "https://omabrowser.org/oma/group/A0A8V1ABN0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1MWW0-1", "protein_name": "Ankyrin repeat and SOCS box protein 6", "gene_name": "ASB6", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPFLHGFRRIIFEYQPLVDAILGSLGIQDPERQEPLDGPSYATSEESRILVLTELLERKAHSPFYQEGVSNALLKMAELGLTRAAAVLLRNGANLNFEDPVTYYTALHIAVLRNQPDMVELLVRHGADINRRDRIHESSPLDLASEEPERLPCLQRLLDLGADVNAADKHGKTALLHALASSDGVQVHNTENIRLLLEGGADVKATTKDGDTVFTCIIFLLGETVGGDKEEAQLINRFCFQVTQLLLAHGADPSECPAHESLTHICLKSFKLHFPLLRFLLESGAAYNCSLHGASCWSGFHIVFERLCSHPGCAEDESHADLLRKAETVLDLMVTSSQKLRLPESFDIHPVGSLADKIQALHSSLRQLESYPPPLKHLCRVCIRLCLQPWPVDAKVKALPLPDRLKWYLLSEHSGAVEDDL", "length": 421 }, "evidence": [ { "id": "A0A8V1ABN0", "url": "https://omabrowser.org/oma/group/A0A8V1ABN0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3IFW1-1", "protein_name": "Ankyrin repeat and SOCS box protein 6 isoform X3", "gene_name": "LOC100771739", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MPFLHGFRRIIFEYQPLVDAILGALGIQDLERQEPLDDYAAGEESRILVLTELLEQKAHSPFYQEGVSNALLKMAELGLTRAAAVLLQSGANLNFEDPVTYYTALHIAVLRNQPDMVELLVRHGADINRRDRIHESSPLDLASEEPERLPCLQRLLDLGADVNAADKNGKTALLHALASSDGVQIHNTDNIRLLLEGGADVKATTKDGDTVFTCIIFLLGETVCGDKEEAPMINRFCFQVTQLLLAHGADPSECPAHESLTHICLKSFKLHFPLLRFLLESGAAYNCSLHGASCWSGFSLIFERLCSHPGCAEDDSHIELLHKAETVLDLMVTSSQRLQLPENFNIHPVGSLAGKIQALHASLRQLESYPPPLKHLCRVSIRLCLRPWPVDTKVKALPLPDRLKWYLLSAHSGTEDNC", "length": 418 }, "evidence": [ { "id": "A0A8V1ABN0", "url": "https://omabrowser.org/oma/group/A0A8V1ABN0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q91ZU1-1", "protein_name": "Ankyrin repeat and SOCS box protein 6", "gene_name": "Asb6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPFLHGFRRIIFEYQPLVDAILGALGIQDLERQEPLDDSASSEESRILVLTELLEQKAHSPFYQEGVSNALLKMAELGLTRAAAVLLQSGANLNFEDPVTYYTALHIAVLRNQPDMVELLVRHGADINRRDRIHESSPLDLASEEPERLPCLQRLLDLGADVNAADKNGKTALLHALASSDGVQIHNTENIRLLLEGGADVKATTKDGDTVFTCIIFLLGETVCGDKEEAPMINRFCFQVTQLLLAHGADPSECPAHESLTHICLKSFKLHFPLLCFLLESGAAYNCSLHGASCWSGFNLVFERLCSHPGCAEDDSHIELLHKAETVLDLMVTSSQRLQLPENLNIHPVGSLAGKIQALHASLRQLESYPPPLKHLCRVSIRLCLRPWPVDTKVKALPLPDRLKWYLLSAHSDTQDTC", "length": 418 }, "evidence": [ { "id": "A0A8V1ABN0", "url": "https://omabrowser.org/oma/group/A0A8V1ABN0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NWX5-1", "protein_name": "Ankyrin repeat and SOCS box protein 6", "gene_name": "ASB6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPFLHGFRRIIFEYQPLVDAILGSLGIQDPERQESLDRPSYVASEESRILVLTELLERKAHSPFYQEGVSNALLKMAELGLTRAADVLLRHGANLNFEDPVTYYTALHIAVLRNQPDMVELLVHHGADVNRRDRIHESSPLDLASEEPERLPCLQRLLDLGADVNAADKHGKTALLHALASSDGVQIHNTENIRLLLEGGADVKATTKDGDTVFTCIIFLLGETVGGDKEEAQMINRFCFQVTRLLLAHGADPSECPAHESLTHICLKSFKLHFPLLRFLLESGAAYNCSLHGASCWSGFHIIFERLCSHPGCTEDESHADLLRKAETVLDLMVTNSQKLQLPENFDIHPVGSLAEKIQALHFSLRQLESYPPPLKHLCRVAIRLYLQPWPVDVKVKALPLPDRLKWYLLSEHSGSVEDDI", "length": 421 }, "evidence": [ { "id": "A0A8V1ABN0", "url": "https://omabrowser.org/oma/group/A0A8V1ABN0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABN0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABN0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 289, "end_pos": 291, "annotation": "n_glycosylation_sequon" }, { "start_pos": 308, "end_pos": 310, "annotation": "n_glycosylation_sequon" }, { "start_pos": 61, "end_pos": 63, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1ABN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABN0" }, { "id": "PS50225", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50225" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SOCS box", "eco_id": "ECO_0000259", "start_pos": 395, "end_pos": 432, "start_aa": "Pro", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 289, "end_pos": 291 }, { "start_pos": 308, "end_pos": 310 }, { "start_pos": 61, "end_pos": 63 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1ABN7-1", "uniprot_ac": "A0A8V1ABN7", "uniprot_id": "A0A8V1ABN7_CHICK", "mass": { "chemical_mass": 45419.0, "monoisotopic_mass": 45419.0 }, "refseq": { "ac": "NP_001026134", "name": "Golgi reassembly-stacking protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026134" }, "gene_names": [ { "name": "GORASP1", "type": "recommended", "evidence": [ { "id": "A0A8V1ABN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABN7" } ] }, { "name": "GORASP1", "type": "synonym", "evidence": [ { "id": "NP_001026134", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026134" } ] } ], "protein_names": [ { "name": "Golgi reassembly stacking protein 1", "type": "synonym", "evidence": [ { "id": "A0A8V1ABN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABN7/entry#names_and_taxonomy" } ] }, { "name": "Golgi reassembly-stacking protein 1", "type": "synonym", "evidence": [ { "id": "NP_001026134", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026134" } ] }, { "name": "golgi reassembly stacking protein 1, 65kDa", "type": "synonym", "evidence": [ { "id": "NP_001026134", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026134" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ720219.1, HAEK01039998.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000035.1. On Sep 23, 2021 this sequence version replaced NP_001026134.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001026134", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026134" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABN7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABN7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "GORASP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABN7", "locus": { "chromosome": "2", "start_pos": 5289071, "end_pos": 5281959, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010026707", "url": "https://www.ensembl.org/id/ENSGALG00010026707" } ] } } ], "crossref": [ { "id": "A0A8V1ABN7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1ABN7", "database": "AlphaFoldDB", "categories": [] }, { "id": "420426", "url": "https://www.ncbi.nlm.nih.gov/gene/420426", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007583", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007583", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024958", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024958", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036034", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036034", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:420426", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420426", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NGYIEAP", "url": "https://omabrowser.org/oma/group/NGYIEAP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ABN7", "url": "https://www.orthodb.org/?gene=A0A8V1ABN7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12893", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12893", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12893:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12893:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04495", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04495", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-162658", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-162658", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-204005", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-204005", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-6807878", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6807878", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001026134", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026134", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1ABN7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABN7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ABN7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABN7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGLGSSSELPDGGAEGFHVHGVQENSPAQQGGLEPFFDFIIAIGHTRLNKENNMLKDLLKANAEKAVKLEVYNIKTMKIREVEVVPSNMWGGQGLLGASVRFCSFQGANEHVWHVLDVEPASPAAVGGLQPYTDYIVGSDQILQESEDFFSLIESHEGKPLKLMVYNTEADSIREVVVTPNGAWGGEGSLGCGIGYGYLHRIPTQSVVSKKKPESKPPSPLPEAGTPVPSTNGYTEAPLLAPTSQSDSSEVVMSLDHSTGQETSGYSPESSLSPPPPLQRVMDPGFLDMSGISLPELTDLTNVSSVSSSASFSMPAAGSFVGTEKLMSNSDPSAYFENTTASGPEDVMKNPEGSGRQPELDHLLPTTSLPSFTLPNEISSKTALETDPQNQETVLINSFESSLAQLKPDDEAAREQKGEEAAQGHE", "length": 426, "header": "tr|A0A8V1ABN7-1|A0A8V1ABN7_CHICK Isoform 1 of Golgi reassembly stacking protein 1 OS=Gallus gallus OX=9031 GN=GORASP1 PE=1 SV=1 CANONICAL=A0A8V1ABN7-1" }, "isoforms": [ { "isoform_ac": "A0A8V1ABN7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABN7/entry#A0A8V1ABN7-1", "sequence": { "sequence": "MGLGSSSELPDGGAEGFHVHGVQENSPAQQGGLEPFFDFIIAIGHTRLNKENNMLKDLLKANAEKAVKLEVYNIKTMKIREVEVVPSNMWGGQGLLGASVRFCSFQGANEHVWHVLDVEPASPAAVGGLQPYTDYIVGSDQILQESEDFFSLIESHEGKPLKLMVYNTEADSIREVVVTPNGAWGGEGSLGCGIGYGYLHRIPTQSVVSKKKPESKPPSPLPEAGTPVPSTNGYTEAPLLAPTSQSDSSEVVMSLDHSTGQETSGYSPESSLSPPPPLQRVMDPGFLDMSGISLPELTDLTNVSSVSSSASFSMPAAGSFVGTEKLMSNSDPSAYFENTTASGPEDVMKNPEGSGRQPELDHLLPTTSLPSFTLPNEISSKTALETDPQNQETVLINSFESSLAQLKPDDEAAREQKGEEAAQGHE", "length": 426, "header": "tr|A0A8V1ABN7-1|A0A8V1ABN7_CHICK Isoform 1 of Golgi reassembly stacking protein 1 OS=Gallus gallus OX=9031 GN=GORASP1 PE=1 SV=1 CANONICAL=A0A8V1ABN7-1" }, "locus": { "chromosome": "2", "start_pos": 5287808, "end_pos": 5282409, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010064813.1", "url": "https://www.ensembl.org/id/ENSGALT00010064813.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039635.1", "url": "https://www.ensembl.org/id/ENSGALP00010039635.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:420426", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420426", "resource": "KEGG Pathway" }, { "id": "R-GGA-162658", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-162658", "resource": "Reactome", "description": "Golgi Cisternae Pericentriolar Stack Reorganization" }, { "id": "R-GGA-204005", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-204005", "resource": "Reactome", "description": "COPII-mediated vesicle transport" }, { "id": "R-GGA-6807878", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6807878", "resource": "Reactome", "description": "COPI-mediated anterograde transport" } ], "orthologs": [ { "uniprot_canonical_ac": "O35254-1", "protein_name": "Golgi reassembly-stacking protein 1", "gene_name": "Gorasp1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGLGASSEQPAGGEGFHLHGVQENSPAQQAGLEPYFDFIITIGHSRLNKENDTLKALLKANVEKPVKLEVFNMKTMRVREVEVVPSNMWGGQGLLGASVRFCSFRRASEHVWHVLDVEPSSPAALAGLRPYTDYIVGSDQILQESEDFFTLIESHEGKPLKLMVYNSESDSCREVTVTPNAAWGGEGSLGCGIGYGYLHRIPTQPSSQYKKPPSASSPGTPAKTPQPNAFPLGAPPPWPIPQDSSGPELGSRQSDYMEALPQVPGGFMEEQLPGPGSPGHGTADYGGCLHSMEIPLQPPPPVQRVMDPGFLDVSGMSLLDSNNTSVCPSLSSSSLLTPTAVSALGPEDIGSSSSSHERGGEATWSGSEFEISFPDSPGSQAQVDHLPRLTLPDGLTSAASPEEGLSAELLEAQTEEPAHTASLDCMAQTEGPAGQVQAAPDPEPGLCEGPW", "length": 451 }, "evidence": [ { "id": "A0A8V1ABN7", "url": "https://omabrowser.org/oma/group/A0A8V1ABN7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q91X51-1", "protein_name": "Golgi reassembly-stacking protein 1", "gene_name": "Gorasp1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLGASSEQPAGGEGFHLHGVQENSPAQQAGLEPYFDFIITIGHSRLNKENDTLKALLKANVEKPVKLEVFNMKTMKVREVEVVPSNMWGGQGLLGASVRFCSFRRASEHVWHVLDVEPSSPAALAGLCPYTDYIVGSDQILQESEDFFTLIESHEGKPLKLMVYNSESDSCREVTVTPNAAWGGEGSLGCGIGYGYLHRIPTQPSSQHKKPPGATPPGTPATTSQLTAFPLGAPPPWPIPQDSSGPELGSRQSDFMEALPQVPGSFMEGQLLGPGSPSHGAADCGGCLRAMEIPLQPPPPVQRVMDPGFLDVSGMSLLDSSNISVCPSLSSSTVLTSTAVSVSGPEDIGSSSSSHERGGEATWSGSEFEISFPDSPGAQAQADHLPRLTLPDGLTSAASPEEGLSAELLEAQTEEPADTASLDCRAETEGRASQAQATPDPEPGL", "length": 446 }, "evidence": [ { "id": "A0A8V1ABN7", "url": "https://omabrowser.org/oma/group/A0A8V1ABN7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9BQQ3-1", "protein_name": "Golgi reassembly-stacking protein 1", "gene_name": "GORASP1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGLGVSAEQPAGGAEGFHLHGVQENSPAQQAGLEPYFDFIITIGHSRLNKENDTLKALLKANVEKPVKLEVFNMKTMRVREVEVVPSNMWGGQGLLGASVRFCSFRRASEQVWHVLDVEPSSPAALAGLRPYTDYVVGSDQILQESEDFFTLIESHEGKPLKLMVYNSKSDSCREVTVTPNAAWGGEGSLGCGIGYGYLHRIPTQPPSYHKKPPGTPPPSALPLGAPPPDALPPGPTPEDSPSLETGSRQSDYMEALLQAPGSSMEDPLPGPGSPSHSAPDPDGLPHFMETPLQPPPPVQRVMDPGFLDVSGISLLDNSNASVWPSLPSSTELTTTAVSTSGPEDICSSSSSHERGGEATWSGSEFEVSFLDSPGAQAQADHLPQLTLPDSLTSAASPEDGLSAELLEAQAEEEPASTEGLDTGTEAEGLDSQAQISTTE", "length": 440 }, "evidence": [ { "id": "A0A8V1ABN7", "url": "https://omabrowser.org/oma/group/A0A8V1ABN7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABN7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABN7" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABN7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABN7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABN7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABN7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "negative regulation of dendrite morphogenesis", "id": "GO:0050774", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050774", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABN7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABN7" } ], "pmid": "" }, { "name": "Golgi ribbon formation", "id": "GO:0090161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090161", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABN7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABN7" } ], "pmid": "" }, { "name": "Golgi organization", "id": "GO:0007030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007030", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABN7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABN7" } ], "pmid": "" }, { "name": "establishment of protein localization to plasma membrane", "id": "GO:0061951", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061951", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABN7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABN7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 302, "end_pos": 304, "annotation": "n_glycosylation_sequon" }, { "start_pos": 338, "end_pos": 340, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1ABN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABN7" }, { "id": "PS51865", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51865" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PDZ GRASP-type", "eco_id": "ECO_0000259", "start_pos": 15, "end_pos": 105, "start_aa": "Glu", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [ { "evidence": [ { "id": "A0A8V1ABN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABN7#function" }, { "id": "A0A8V1ABN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABN7" }, { "id": "PIRSR607583-1", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR607583-1" } ], "binding_site_uniprot": 103, "amino_acid": "Cys", "chebi_lig_id": "CHEBI_29105", "ligand": "Zn(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 103, "end_pos": 103, "start_aa": "Cys", "end_aa": "Cys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1ABN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABN7#function" }, { "id": "A0A8V1ABN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABN7" }, { "id": "PIRSR607583-1", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR607583-1" } ], "binding_site_uniprot": 18, "amino_acid": "His", "chebi_lig_id": "CHEBI_29105", "ligand": "Zn(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 18, "end_pos": 18, "start_aa": "His", "end_aa": "His", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1ABN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABN7#function" }, { "id": "A0A8V1ABN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABN7" }, { "id": "PIRSR607583-1", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR607583-1" } ], "binding_site_uniprot": 20, "amino_acid": "His", "chebi_lig_id": "CHEBI_29105", "ligand": "Zn(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 20, "end_pos": 20, "start_aa": "His", "end_aa": "His", "glycosite_overlap": "" } ], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 302, "end_pos": 304 }, { "start_pos": 338, "end_pos": 340 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { 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"o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1ABP0-1", "uniprot_ac": "A0A8V1ABP0", "uniprot_id": "A0A8V1ABP0_CHICK", "mass": { "chemical_mass": 85633.0, "monoisotopic_mass": 85633.0 }, "refseq": {}, "gene_names": [ { "name": "CBARP", "type": "recommended", "evidence": [ { "id": "A0A8V1ABP0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP0" } ] } ], "protein_names": [ { "name": "CACN subunit beta associated regulatory protein", "type": "synonym", "evidence": [ { "id": "A0A8V1ABP0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP0/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABP0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CBARP", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP0", "locus": { "chromosome": "28", "start_pos": 3465496, "end_pos": 3471305, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028013", "url": "https://www.ensembl.org/id/ENSGALG00010028013" } ] } } ], "crossref": [ { "id": "A0A8V1ABP0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1ABP0", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR037658", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037658", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ABP0", "url": "https://www.orthodb.org/?gene=A0A8V1ABP0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AEJ1", "url": "https://www.orthodb.org/?gene=A0A8V1AEJ1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR28597", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28597", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR28597:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28597:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF27937", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27937", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1ABP0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ABP0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AEJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEJ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AEJ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEJ1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "METEFLHHRRSAAAFPSRPGQGVPADVPGLDRTMNDDPTPWDNATESSTALPGEVSPQDGYVLLLALLSIFIGGTLVLLSGILIVCRRCCEADRRHSRASDDPEKTTTTYLDDSQPAQDITIKVEDPECLSASSYRDAESERFLSSSSSSARRVSFNEAALYEQGKKTQEKGRRYTLTEGDFHHLKNARLTHLHLPPPALKIVTIHECESSENSLAMTPRRPPPKPGLAIFQPPGGAVPQPGHAVCPSSALPGDTYNSTAGGSPATSSDSGEGPSFTAAPRTGKGPMVGSASPGEAPPAPTQGPVLQFFTRLRRHASLDGASPYFRIKKWKLESTQRASSLDTRGSPKRRQFQRQRAASESMDQEDRDPHQTDIIQYIAHTDDVAFHPAGGPFLPSPSSPPPSLGRLEPGEDGPSEAAAPEQRSVGHDIWSLRASLELYAASERSNDQDSVRSDGADSVSSGGAAPCPSSSLDEAEGPDEKLWARPKAEESEPGTRKLLQMDSGYASIEAPGRGGEEGPPADQTASEKRICFTSAGRKGTIFESFEGREPDEEEEDEEEDEEDEARRGAVGGGRPGAHPQPPGVVPVRADADGSGRAVAAEGLQHRREDGRAVQRLRAARPAVRRVPAARKAPLPHAPPQAVAARQAVQRPGGAIPRAGAAPHPSAPRGQRQLPAGRPLPRPAAPHRQRRGRRGGRGGRRRRSAARSRHSGDRGGARRGAPGRARARRRGGVPRTRAVRGAAARRGAAGQDNGRHRGAAVRASAEGGGGAAGGDGERGGRNCRRRAPRPQPRVGRTRCGSARCAGG", "length": 806, "header": "tr|A0A8V1ABP0-1|A0A8V1ABP0_CHICK Isoform 1 of CACN subunit beta associated regulatory protein OS=Gallus gallus OX=9031 GN=CBARP PE=4 SV=1 CANONICAL=A0A8V1ABP0-1" }, "isoforms": [ { "isoform_ac": "A0A8V1ABP0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP0/entry#A0A8V1ABP0-1", "sequence": { "sequence": "METEFLHHRRSAAAFPSRPGQGVPADVPGLDRTMNDDPTPWDNATESSTALPGEVSPQDGYVLLLALLSIFIGGTLVLLSGILIVCRRCCEADRRHSRASDDPEKTTTTYLDDSQPAQDITIKVEDPECLSASSYRDAESERFLSSSSSSARRVSFNEAALYEQGKKTQEKGRRYTLTEGDFHHLKNARLTHLHLPPPALKIVTIHECESSENSLAMTPRRPPPKPGLAIFQPPGGAVPQPGHAVCPSSALPGDTYNSTAGGSPATSSDSGEGPSFTAAPRTGKGPMVGSASPGEAPPAPTQGPVLQFFTRLRRHASLDGASPYFRIKKWKLESTQRASSLDTRGSPKRRQFQRQRAASESMDQEDRDPHQTDIIQYIAHTDDVAFHPAGGPFLPSPSSPPPSLGRLEPGEDGPSEAAAPEQRSVGHDIWSLRASLELYAASERSNDQDSVRSDGADSVSSGGAAPCPSSSLDEAEGPDEKLWARPKAEESEPGTRKLLQMDSGYASIEAPGRGGEEGPPADQTASEKRICFTSAGRKGTIFESFEGREPDEEEEDEEEDEEDEARRGAVGGGRPGAHPQPPGVVPVRADADGSGRAVAAEGLQHRREDGRAVQRLRAARPAVRRVPAARKAPLPHAPPQAVAARQAVQRPGGAIPRAGAAPHPSAPRGQRQLPAGRPLPRPAAPHRQRRGRRGGRGGRRRRSAARSRHSGDRGGARRGAPGRARARRRGGVPRTRAVRGAAARRGAAGQDNGRHRGAAVRASAEGGGGAAGGDGERGGRNCRRRAPRPQPRVGRTRCGSARCAGG", "length": 806, "header": "tr|A0A8V1ABP0-1|A0A8V1ABP0_CHICK Isoform 1 of CACN subunit beta associated regulatory protein OS=Gallus gallus OX=9031 GN=CBARP PE=4 SV=1 CANONICAL=A0A8V1ABP0-1" }, "locus": { "chromosome": "28", "start_pos": 3470792, "end_pos": 3466500, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067901.1", "url": "https://www.ensembl.org/id/ENSGALT00010067901.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041644.1", "url": "https://www.ensembl.org/id/ENSGALP00010041644.1" } ] } }, { "isoform_ac": "A0A8V1AEJ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP0/entry#A0A8V1AEJ1-1", "sequence": { "sequence": "MNDDPTPWDNATESSTALPGEVSPQDGYVLLLALLSIFIGGTLVLLSGILIVCRRCCEADRRHSRASDDPEKTTTTYLDDSQPAQDITIKVEDPECLSASSYRDAESERFLSSSSSSARRVSFNEAALYEQGKKTQEKGRRYTLTEGDFHHLKNARLTHLHLPPPALKIVTIHECESSENSLAMTPRRPPPKPGLAIFQPPGGAVPQPGHAVCPSSALPGDTYNSTAGGSPATSSDSGEGPSFTAAPRTGKGPMVGSASPGEAPPAPTQGPVLQFFTRLRRHASLDGASPYFRIKKWKLESTQRASSLDTRGSPKRRQFQRQRAASESMDQEDRDPHQTDIIQYIAHTDDVAFHPAGGPFLPSPSSPPPSLGRLEPGEDGPSEAAAPEQRSVGHDIWSLRASLELYAASERSNDQDSVRSDGADSVSSGGAAPCPSSSLDEAEGPDEKLWARPKAEESEPGTRKLLQMDSGYASIEAPGRGGEEGPPADQTASEKRICFTSAGRKGTIFESFEGREPDEEEEDEEEDEEDEARRGAVGGGRPGAHPQPPGVVPVRADADGSGRAVAAEGLQHRREDGRAVQRLRAARPAVRRVPAARKAPLPHAPPQAVAARQAVQRPGGAIPRAGAAPHPSAPRGQRQLPAGRPLPRPAAPHRQRRGRRGGRGGRRRRSAARSRHSGDRGGARRGAPGRARARRRGGVPRTRAVRGAAARRGAAGQDNGRHRGAAVRASAEGGGGAAGGDGERGGRNCRRRAPRPQPRVGRTRCGSARCAGG", "length": 773, "header": "tr|A0A8V1AEJ1-1|A0A8V1AEJ1_CHICK Computationally mapped isoform of CACN subunit beta associated regulatory protein OS=Gallus gallus OX=9031 GN=CBARP PE=4 SV=1 CANONICAL=A0A8V1ABP0-1" }, "locus": { "chromosome": "28", "start_pos": 3470086, "end_pos": 3466500, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067909.1", "url": "https://www.ensembl.org/id/ENSGALT00010067909.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041652.1", "url": "https://www.ensembl.org/id/ENSGALP00010041652.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 301, "start_aa": "Thr", "end_pos": 301, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr301", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABP0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP0" } ], "pmid": "" }, { "name": "secretory granule", "id": "GO:0030141", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030141", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABP0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP0" } ], "pmid": "" }, { "name": "growth cone", "id": "GO:0030426", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030426", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABP0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "transmembrane transporter binding", "id": "GO:0044325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044325", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABP0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "negative regulation of calcium ion-dependent exocytosis", "id": "GO:0045955", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045955", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABP0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP0" } ], "pmid": "" }, { "name": "negative regulation of calcium ion transmembrane transport", "id": "GO:1903170", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903170", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABP0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 257, "end_pos": 259, "annotation": "n_glycosylation_sequon" }, { "start_pos": 43, "end_pos": 45, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 301 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 257, "end_pos": 259 }, { "start_pos": 43, "end_pos": 45 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1ABP8-1", "uniprot_ac": "A0A8V1ABP8", "uniprot_id": "A0A8V1ABP8_CHICK", "mass": { "chemical_mass": 70129.0, "monoisotopic_mass": 70129.0 }, "refseq": { "ac": "XP_418495", "name": "kelch-like protein 40", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418495" }, "gene_names": [ { "name": "KLHL40", "type": "recommended", "evidence": [ { "id": "A0A8V1ABP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP8" } ] }, { "name": "KLHL40", "type": "synonym", "evidence": [ { "id": "XP_418495", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418495" } ] } ], "protein_names": [ { "name": "Kelch like family member 40", "type": "synonym", "evidence": [ { "id": "A0A8V1ABP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP8/entry#names_and_taxonomy" } ] }, { "name": "kelch-like protein 40", "type": "synonym", "evidence": [ { "id": "XP_418495", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418495" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052533.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Nov 16, 2006 this sequence version replaced XP_418495.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_418495", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418495" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABP8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "KLHL40", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP8", "locus": { "chromosome": "2", "start_pos": 2041570, "end_pos": 2051409, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027381", "url": "https://www.ensembl.org/id/ENSGALG00010027381" } ] } } ], "crossref": [ { "id": "A0A8V1ABP8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1ABP8", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd18340", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18340", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18516", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18516", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "420389", "url": "https://www.ncbi.nlm.nih.gov/gene/420389", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006652", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006652", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011705", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011705", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015915", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015915", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017096", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017096", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030607", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030607", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:420389", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420389", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RNFACER", "url": "https://omabrowser.org/oma/group/RNFACER/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ABP8", "url": "https://www.orthodb.org/?gene=A0A8V1ABP8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24412", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24412", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24412:SF22", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24412:SF22", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00651", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00651", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07707", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07707", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24681", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24681", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_418495", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418495", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1ABP8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ABP8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGLPFDQVEELRLYQQTLLQDGLKDMLDHNKFLDCVLKVKGKEFPCHRLVLAACSPYFRAMFLSDMEESKKREVSLEDVDPDVMGKILHYIYTSELEITEQNVQDIFSVANMFQIPSIFTVCVSFLQKRLCLSNCLAIFRLGLMLDCARLAVAARDFICDRFALVSRDEEFYQLSPDELIAIISSDSLNIEKEENVFEVVMKWVGTKDQESRQKALPVVFESIRFRLMPKDYIKDHVEKQAVVKSSPELLKKLQMVKDAQQGKFTVVKKKKVKKSDEKQAKGNVVNGAVDEEEDTEEDALPGILNDTMRFGMFLQDLIFMVSDSGAVAYDPTANECYFASLSAQIPKNHVSLVTKENQIFIVGGLYYNEDSKEDPMSSYFLQYDHLDSDWLGMPPLPSPRCLFGLGEAENSIFVVGGKELKEGEKTLDSVLCYDRLSFKWGEADSLPYAVYGHAVVSHKDLVYVIGGKGSDKKCLKKMCVYNPNKFEWKELAPMKTARSLFGATVHKDKIYVAAGVTDSGLTNSVEVYDIATNKWDTFPEFPQERSSVSLVSLSGVLYLLGGFATVETESGELVPTELNDVWRYDEEQKKWEGVLREIQYASGATFLPVRLNVLRLTKM", "length": 619, "header": "tr|A0A8V1ABP8-1|A0A8V1ABP8_CHICK Isoform 1 of Kelch like family member 40 OS=Gallus gallus OX=9031 GN=KLHL40 PE=3 SV=1 CANONICAL=A0A8V1ABP8-1" }, "isoforms": [ { "isoform_ac": "A0A8V1ABP8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP8/entry#A0A8V1ABP8-1", "sequence": { "sequence": "MGLPFDQVEELRLYQQTLLQDGLKDMLDHNKFLDCVLKVKGKEFPCHRLVLAACSPYFRAMFLSDMEESKKREVSLEDVDPDVMGKILHYIYTSELEITEQNVQDIFSVANMFQIPSIFTVCVSFLQKRLCLSNCLAIFRLGLMLDCARLAVAARDFICDRFALVSRDEEFYQLSPDELIAIISSDSLNIEKEENVFEVVMKWVGTKDQESRQKALPVVFESIRFRLMPKDYIKDHVEKQAVVKSSPELLKKLQMVKDAQQGKFTVVKKKKVKKSDEKQAKGNVVNGAVDEEEDTEEDALPGILNDTMRFGMFLQDLIFMVSDSGAVAYDPTANECYFASLSAQIPKNHVSLVTKENQIFIVGGLYYNEDSKEDPMSSYFLQYDHLDSDWLGMPPLPSPRCLFGLGEAENSIFVVGGKELKEGEKTLDSVLCYDRLSFKWGEADSLPYAVYGHAVVSHKDLVYVIGGKGSDKKCLKKMCVYNPNKFEWKELAPMKTARSLFGATVHKDKIYVAAGVTDSGLTNSVEVYDIATNKWDTFPEFPQERSSVSLVSLSGVLYLLGGFATVETESGELVPTELNDVWRYDEEQKKWEGVLREIQYASGATFLPVRLNVLRLTKM", "length": 619, "header": "tr|A0A8V1ABP8-1|A0A8V1ABP8_CHICK Isoform 1 of Kelch like family member 40 OS=Gallus gallus OX=9031 GN=KLHL40 PE=3 SV=1 CANONICAL=A0A8V1ABP8-1" }, "locus": { "chromosome": "2", "start_pos": 2051227, "end_pos": 2042658, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066384.1", "url": "https://www.ensembl.org/id/ENSGALT00010066384.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040650.1", "url": "https://www.ensembl.org/id/ENSGALP00010040650.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:420389", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420389", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D4AA43-1", "protein_name": "Kelch-like family member 40", "gene_name": "Klhl40", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTLGLEQAEEQRLYQQTLLQDGLKDMLDHGKFLDCVVRVGEREFPCHRLVLAACSPYFRARFLAEPDGAGELRLEEVSPDVVSQVLHYLYTSEIALDEASVQDLFAAAHRFQIPSIFTICVSFLQKRLCLANCLAVFRLGLLLDCARLAVAARDFICARFPLVARDNDFLGLSADELIAIISSDGLNVEKEEAVFEAVMRWASSGDADVQAEHQRALPTVFESIRCRLLPRAFLESRVERHPLVRSQPELLRKVQMVKDAHEGRLTTLRKKKKEKGEQTARTKEANQGTEDTKAEDDEERVLPGILNDTLRFGMFLQDLIFMISEEGAVAYDPAANECYCASLSTQIPKNHVSLVTKENQVFVAGGLFYNEDNKEDPMSAYFLQFDHLDSEWLGMPPLPSPRCLFGLGEALNAIYVVGGRELKDSEDSLDSVLCYDRLSFKWGESDPLPYAVYGHSVLSHMDLVYVIGGKGKDRKCLNKMCVYDPKKFEWKELAPMKTARSLFGATVHDGRIFVAAGVTDTGLTSSTEVYSIADNKWTPFEAFPQERSSLSLVSLAGTLYALGGFATLETESGELVPTELNDIWRFNEDEKKWEGVLREIAYAAGATFLPVRLNVLRLTKM", "length": 621 }, "evidence": [ { "id": "A0A8V1ABP8", "url": "https://omabrowser.org/oma/group/A0A8V1ABP8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E9QJ30-1", "protein_name": "Kelch-like protein 40b", "gene_name": "klhl40b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MALPIDPMEEPRMYQQTLLQDGLYDLLESDMMVDCVLKIKDKEFPCHRLVLAACSSYFRAFFKSGVEESKQREIVLEDVEPGVMGIILKYLYTSNINVTEQNVQDIFALSNMLQIPSIFTVCVSFLQKRLSLSNCLAIFRLGLMLDCPRLAISARNFACERFQFITRDEEFLQLTPSELAAVLASDSLNVETEQDVFEALIKWVGHDQENRIGDLPDLLDCIRLRLVPRDYFVKNVEKHEWLSSNPEITKKLQLVKDAHAGKLPELKKTKNKKSPSEEGQKKGDEEEVEEEEEQEERLPGILNDNLRFGMFLRELIFLINDSASVAYDPTGNDCYVASVSTQIPKNHCSLVTKENQIFVAGGLFFDEQSKDEQIYSYFLQFDPASSDWMGMPPIPSPRFLFGMGEAENFIFVIGGREMKEGENILNTVMVYDRQFLKWAESDPLPYLVYGHGVVSHNEMIYVIGGKGENKECLNRVCAYDIKTHQWKDLAPLNTARSLFGVTIHKNNIYVVAGVTDSGLTGSAEVYDIKTNKWSEFVEFPQDRSSLSLVSVSGVLYAVGGFAMFPKEDSDDLMPLEMNDIWRYDESERTWSGILRENRYASGATVLGVRLNTLRLTKM", "length": 618 }, "evidence": [ { "id": "A0A8V1ABP8", "url": "https://omabrowser.org/oma/group/A0A8V1ABP8/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q2TBA0-1", "protein_name": "Kelch-like protein 40", "gene_name": "KLHL40", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MALGLEQAEEQRLYQQTLLQDGLKDMLDHGKFLDCVVRAGEREFPCHRLVLAACSPYFRARFLAEPERAGELHLEEVSPDVVAQVLHYLYTSEIALDEASVQDLFAAAHRFQIPSIFTICVSFLQKRLCLSNCLAVFRLGLLLDCARLAVAARDFICAHFTLVARDADFLGLSADELIAIISSDGLNVEKEEAVFEAVMRWAGSGDAEAQAERQRALPTVFESVRCRLLPRAFLESRVERHPLVRAQPELLRKVQMVKDAHEGRITTLRKKKKGKDGAGAKEADKGTSKAKAEEDEEAERILPGILNDTLRFGMFLQDLIFMISEEGAVAYDPAANECYCASLSNQVPKNHVSLVTKENQVFVAGGLFYNEDNKEDPMSAYFLQFDHLDSEWLGMPPLPSPRCLFGLGEALNSIYVVGGREIKDGERCLDSVMCYDRLSFKWGESDPLPYVVYGHTVLSHMDLVYVIGGKGSDRKCLNKMCVYDPKKFEWKELAPMQTARSLFGATVHDGRIIVAAGVTDTGLTSSAEVYSITDNKWAPFEAFPQERSSLSLVSLVGTLYAIGGFATLETESGELVPTELNDIWRYNEEEKKWEGVLREIAYAAGATFLPVRLNVLCLTKM", "length": 621 }, "evidence": [ { "id": "A0A8V1ABP8", "url": "https://omabrowser.org/oma/group/A0A8V1ABP8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9D783-1", "protein_name": "Kelch-like protein 40", "gene_name": "Klhl40", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTLGLEQAEEQRLYQQTLLQDGLKDMLDHGKFLDCVVRVGEREFPCHRLVLAACSPYFRARFLAEPDSAGEVRLEEVSPDVVSQVLHYLYTSEIALDEASVQDLFAAAHRFQIPSIFTICVSFLQKRLCLANCLAVFRLGLLLDCARLAVAARDFICARFPLVARDNDFLGLSADELIAIISSDGLNVEKEEAVFEAVMRWASSGDAEAQAERQRALPTVFESVRCRLLPRAFLETRVERHPLVRSQPELLRKVQMVKDAHEGRLTTLRKKKKEKGEQTARAKEANQGTEDTKAEDDEERVLPGILNDTLRFGMFLQDLIFMISEEGAVAYDPAANECYCASLSTQIPKNHVSLVTKENQVFVAGGLFYNEDNKEDPMSAYFLQFDHLDSEWLGMPPLPSPRCLFGLGEALNAIYVVGGRELKDSEDSLDSVLCYDRLSFKWGESDPLPYAVYGHTVLSHMDLVYVIGGKGKDRKCLNKMCVYDPKKFEWKELAPMQTARSLFGATVHDGRIFVAAGVTDTGLTSSSEVYSIADNKWTSFEAFPQERSSLSLVSLAGTLYALGGFATLETESGELVPTELNDIWRYNEDEKKWEGVLREIAYAAGATFLPVRLNVVRLTKM", "length": 621 }, "evidence": [ { "id": "A0A8V1ABP8", "url": "https://omabrowser.org/oma/group/A0A8V1ABP8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABP8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP8" } ], "pmid": "" }, { "name": "I band", "id": "GO:0031674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031674", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABP8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP8" } ], "pmid": "" }, { "name": "A band", "id": "GO:0031672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031672", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABP8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP8" } ], "pmid": "" }, { "name": "Cul3-RING ubiquitin ligase complex", "id": "GO:0031463", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031463", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABP8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABP8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP8" } ], "pmid": "" }, { "name": "skeletal muscle fiber development", "id": "GO:0048741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048741", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABP8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP8" } ], "pmid": "" }, { "name": "negative regulation of protein ubiquitination", "id": "GO:0031397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031397", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABP8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP8" } ], "pmid": "" }, { "name": "negative regulation of proteasomal ubiquitin-dependent protein catabolic process", "id": "GO:0032435", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032435", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABP8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "ubiquitin-like ligase-substrate adaptor activity", "id": "GO:1990756", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990756", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABP8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 305, "end_pos": 307, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1ABP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP8" }, { "id": "PS50097", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50097" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BTB", "eco_id": "ECO_0000259", "start_pos": 33, "end_pos": 100, "start_aa": "Leu", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 305, "end_pos": 307 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1ABQ5-1", "uniprot_ac": "A0A8V1ABQ5", "uniprot_id": "A0A8V1ABQ5_CHICK", "mass": { "chemical_mass": 32981.0, "monoisotopic_mass": 32981.0 }, "refseq": { "ac": "NP_001384420", "name": "Krueppel-like factor 7", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384420" }, "gene_names": [ { "name": "KLF7", "type": "recommended", "evidence": [ { "id": "A0A8V1ABQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABQ5" } ] }, { "name": "KLF7", "type": "synonym", "evidence": [ { "id": "NP_001384420", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384420" } ] } ], "protein_names": [ { "name": "Krueppel-like factor 7", "type": "recommended", "evidence": [ { "id": "A0A8V1ABQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABQ5/entry#names_and_taxonomy" } ] }, { "name": "Krueppel-like factor 7", "type": "synonym", "evidence": [ { "id": "NP_001384420", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384420" } ] }, { "name": "Kruppel-like factor 7 (ubiquitous)", "type": "synonym", "evidence": [ { "id": "NP_001384420", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384420" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR13267659.208572.1, SRR13267655.232960.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000236.1 and JQ736790.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001384420", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384420" } ] }, { "annotation": "DNA methylation of CpG sites in the chicken KLF7 promoter and Exon 2 in association with mRNA expression in abdominal adipose tissue and blood metabolic indicators. Publication Status: Online-Only", "evidence": [ { "database": "RefSeq", "id": "NP_001384420", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384420" }, { "database": "PubMed", "id": "33054719", "url": "https://glygen.org/publication/PubMed/33054719" } ] }, { "annotation": "Data indicate that Kruppel-like factor 7 (Klf7) was more highly expressed in preadipocytes than in mature adipocytes.", "evidence": [ { "database": "RefSeq", "id": "NP_001384420", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384420" }, { "database": "PubMed", "id": "23439665", "url": "https://glygen.org/publication/PubMed/23439665" } ] }, { "annotation": "Transcriptional control of chicken KLF7 promoter in preadipocytes.", "evidence": [ { "database": "RefSeq", "id": "NP_001384420", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384420" }, { "database": "PubMed", "id": "33330912", "url": "https://glygen.org/publication/PubMed/33330912" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABQ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABQ5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "KLF7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABQ5", "locus": { "chromosome": "7", "start_pos": 11940382, "end_pos": 11883406, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010025822", "url": "https://www.ensembl.org/id/ENSGALG00010025822" } ] } } ], "crossref": [ { "id": "A0A8V1ABQ5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1ABQ5", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd21585", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21585", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "429011", "url": "https://www.ncbi.nlm.nih.gov/gene/429011", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "DCFLHAA", "url": "https://omabrowser.org/oma/group/DCFLHAA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ABQ5", "url": "https://www.orthodb.org/?gene=A0A8V1ABQ5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23235", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23235", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23235:SF77", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23235:SF77", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001384420", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384420", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1ABQ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABQ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ABQ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABQ5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDVLASYSIFQELQLVHDTGYFSALPSLEENWQQTCLELERYLQTEPRKISESFGEDLDCFLHASSAPDAEDSIRRLDPILLPVETSMCDKGANMDIILSRDKLLSETCLSLQSTSSSTESYTAVNQAQLNAVTSLTPPSSPELSRHLVKTSQTLSAVDGTVTLKLVAKKSSLGSMKVSVAAATAGTIKSGQSDSEQGGPGLEASPENKKRVHRCQFNGCRKVYTKSSHLKAHQRTHTGEKPYKCSWEGCEWRFARSDELTRHYRKHTGAKPFKCNHCDRCFSRSDHLALHMKRHI", "length": 296, "header": "tr|A0A8V1ABQ5-1|A0A8V1ABQ5_CHICK Isoform 1 of Krueppel-like factor 7 OS=Gallus gallus OX=9031 GN=KLF7 PE=3 SV=1 CANONICAL=A0A8V1ABQ5-1" }, "isoforms": [ { "isoform_ac": "A0A8V1ABQ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABQ5/entry#A0A8V1ABQ5-1", "sequence": { "sequence": "MDVLASYSIFQELQLVHDTGYFSALPSLEENWQQTCLELERYLQTEPRKISESFGEDLDCFLHASSAPDAEDSIRRLDPILLPVETSMCDKGANMDIILSRDKLLSETCLSLQSTSSSTESYTAVNQAQLNAVTSLTPPSSPELSRHLVKTSQTLSAVDGTVTLKLVAKKSSLGSMKVSVAAATAGTIKSGQSDSEQGGPGLEASPENKKRVHRCQFNGCRKVYTKSSHLKAHQRTHTGEKPYKCSWEGCEWRFARSDELTRHYRKHTGAKPFKCNHCDRCFSRSDHLALHMKRHI", "length": 296, "header": "tr|A0A8V1ABQ5-1|A0A8V1ABQ5_CHICK Isoform 1 of Krueppel-like factor 7 OS=Gallus gallus OX=9031 GN=KLF7 PE=3 SV=1 CANONICAL=A0A8V1ABQ5-1" }, "locus": { "chromosome": "7", "start_pos": 11936572, "end_pos": 11883682, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010062959.1", "url": "https://www.ensembl.org/id/ENSGALT00010062959.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038883.1", "url": "https://www.ensembl.org/id/ENSGALP00010038883.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Klf7 modulates the differentiation and proliferation of chicken preadipocyte.", "journal": "Acta biochimica et biophysica Sinica", "date": "2013-04", "authors": "Zhang Zhiwei, Wang Haixia, Sun Yingning, Li Hui, Wang Ning", "evidence": [ { "database": "RefSeq", "id": "NP_001384420", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384420" } ], "reference": [ { "type": "PubMed", "id": "23439665", "url": "https://glygen.org/publication/PubMed/23439665" } ] }, { "title": "DNA methylation of CpG sites in the chicken KLF7 promoter and Exon 2 in association with mRNA expression in abdominal adipose tissue and blood metabolic indicators.", "journal": "BMC genetics", "date": "2020-10-14", "authors": "Zhang Zhiwei, Nie Cunxi, Chen Yuechan, Dong Yanzhe, Lin Tao", "evidence": [ { "database": "RefSeq", "id": "NP_001384420", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384420" } ], "reference": [ { "type": "PubMed", "id": "33054719", "url": "https://glygen.org/publication/PubMed/33054719" } ] }, { "title": "Transcriptional control of chicken KLF7 promoter in preadipocytes.", "journal": "Acta biochimica et biophysica Sinica", "date": "2021-02-04", "authors": "Lin Tao, Chen Yuechan, Zhang Yanling, Li Yaoyao, Gao Lingyu, Zhang Zhiwei", "evidence": [ { "database": "RefSeq", "id": "NP_001384420", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384420" } ], "reference": [ { "type": "PubMed", "id": "33330912", "url": "https://glygen.org/publication/PubMed/33330912" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "M0RCR2-1", "protein_name": "Krueppel-like factor 7", "gene_name": "Klf7", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDVLASYSIFQELQLVHDTGYFSALPSLEETWQQTCLELERYLQTEPRRISETFGEDLDCFLHASPPPCIEESFRRLDPLLLPVEATICEKSSAVDILLSRDKLLSETCLSLQPTSSSLDSYTAVNQAQLNAVTSLTPPSSPELSRHLVKTSQTLSAVDGTVTLKLVAKKASLSSVKVGGVAAAAAVTPAGAVKSGQSDSEQGGGGADTCPENKKRVHRCQFNGCRKVYTKSSHLKAHQRTHTGSGEKPYKCSWEGCEWRFARSDELTRHYRKHTGAKPFKCNHCDRCFSRSDHLALHMKRHI", "length": 303 }, "evidence": [ { "id": "A0A8V1ABQ5", "url": "https://omabrowser.org/oma/group/A0A8V1ABQ5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O75840-1", "protein_name": "Krueppel-like factor 7", "gene_name": "KLF7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDVLASYSIFQELQLVHDTGYFSALPSLEETWQQTCLELERYLQTEPRRISETFGEDLDCFLHASPPPCIEESFRRLDPLLLPVEAAICEKSSAVDILLSRDKLLSETCLSLQPASSSLDSYTAVNQAQLNAVTSLTPPSSPELSRHLVKTSQTLSAVDGTVTLKLVAKKAALSSVKVGGVATAAAAVTAAGAVKSGQSDSDQGGLGAEACPENKKRVHRCQFNGCRKVYTKSSHLKAHQRTHTGEKPYKCSWEGCEWRFARSDELTRHYRKHTGAKPFKCNHCDRCFSRSDHLALHMKRHI", "length": 302 }, "evidence": [ { "id": "A0A8V1ABQ5", "url": "https://omabrowser.org/oma/group/A0A8V1ABQ5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q99JB0-1", "protein_name": "Krueppel-like factor 7", "gene_name": "Klf7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDVLASYSIFQELQLVHDTGYFSALPSLEETWQQTCLELERYLQTEPRRISETFGEDLDCFLHASPPPCIEESFRRLDPLLLPVEATICEKSSAVDILLSRDKLLSETCLSLQPTSSSLDSYTAVNQAQLNAVTSLTPPSSPELSRHLVKTSQTLSAVDGTVTLKLVAKKASLSSVKVGGVAAAAAVTPAGAVKSGQSDSEQGGGGADTCPENKKRVHRCQFNGCRKVYTKSSHLKAHQRTHTGEKPYKCSWEGCEWRFARSDELTRHYRKHTGAKPFKCNHCDRCFSRSDHLALHMKRHI", "length": 301 }, "evidence": [ { "id": "A0A8V1ABQ5", "url": "https://omabrowser.org/oma/group/A0A8V1ABQ5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "regulation of epidermal cell differentiation", "id": "GO:0045604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045604", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABQ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABQ5" } ], "pmid": "" }, { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABQ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABQ5" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABQ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABQ5" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABQ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABQ5" } ], "pmid": "" }, { "name": "glucose homeostasis", "id": "GO:0042593", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042593", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABQ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABQ5" } ], "pmid": "" }, { "name": "negative regulation of insulin secretion involved in cellular response to glucose stimulus", "id": "GO:0061179", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061179", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABQ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABQ5" } ], "pmid": "" }, { "name": "negative regulation of adipose tissue development", "id": "GO:1904178", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904178", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABQ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABQ5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABQ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABQ5" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABQ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABQ5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABQ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABQ5" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABQ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABQ5" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABQ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABQ5" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABQ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABQ5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1ABQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABQ5" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 213, "end_pos": 242, "start_aa": "His", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8V1ABQ8-1", "uniprot_ac": "A0A8V1ABQ8", "uniprot_id": "A0A8V1ABQ8_CHICK", "mass": { "chemical_mass": 57760.0, "monoisotopic_mass": 57760.0 }, "refseq": { "ac": "NP_001186505", "name": "protein-cysteine N-palmitoyltransferase HHAT-like protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186505" }, "gene_names": [ { "name": "HHATL", "type": "recommended", "evidence": [ { "id": "A0A8V1ABQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABQ8" } ] }, { "name": "HHATL", "type": "synonym", "evidence": [ { "id": "NP_001186505", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186505" } ] } ], "protein_names": [ { "name": "Hedgehog acyltransferase-like", "type": "synonym", "evidence": [ { "id": "A0A8V1ABQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABQ8/entry#names_and_taxonomy" } ] }, { "name": "protein-cysteine N-palmitoyltransferase HHAT-like protein", "type": "synonym", "evidence": [ { "id": "NP_001186505", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186505" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR13267649.247776.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN05341171 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000035.1. On Sep 23, 2021 this sequence version replaced NP_001186505.1. Sequence Note: This RefSeq record was created from transcripts from different strains and genomic sequence data because no single transcript from the same strain was available for the full length of the gene. The extent of this transcript is supported by transcript alignments and orthologous data.", "evidence": [ { "database": "RefSeq", "id": "NP_001186505", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186505" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABQ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABQ8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "HHATL", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABQ8", "locus": { "chromosome": "2", "start_pos": 2054936, "end_pos": 2068447, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027384", "url": "https://www.ensembl.org/id/ENSGALG00010027384" } ] } } ], "crossref": [ { "id": "A0A8V1ABQ8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1ABQ8", "database": "AlphaFoldDB", "categories": [] }, { "id": "420391", "url": "https://www.ncbi.nlm.nih.gov/gene/420391", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004299", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004299", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051085", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051085", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:420391", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420391", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HRAVMYM", "url": "https://omabrowser.org/oma/group/HRAVMYM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ABQ8", "url": "https://www.orthodb.org/?gene=A0A8V1ABQ8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13285", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13285", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13285:SF19", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13285:SF19", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03062", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03062", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001186505", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186505", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1ABQ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABQ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ABQ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABQ8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGVKAMLPSHELGFYALVVTCAVLYSSSGIFEASRDSMNRKAFRDGIKPGWHYFGRKMDVADFEWVMWFTSFRNVIIFTLSGHVLFAKVCSMTVPQHRAVVYMLYGMLAVLGSMGLAYLMIILSHCLILYSVALSKQKWLCYVAGLCCLASIKLEPFSSWQSGFVTGAFDLQDVLFYGGSGFTIMRCMSFALESSERQEGIFSIFDLLKYNFYLPFFFFGPVMTFDQFHSQVSTRDLRRKEDEMRNIRVHALLHVGAIIAVDIFFHFFYILTLPSDLKFVNRLSDWALAGLAYSNLVYDWVKAAVMFGVINTIARLDHLDPPQPPKCITMLYVFAETHFDRGINDWLCKYVYDHIGENHDNVMKELMATIATFAVTTLWLGPCEIVYIWSVFNCFGLNFELWVQKFFQWEPLSKLEAKMSEATSRRIRAVFGAANFWAIVLYNILALNSLEFALLVTRRLLVTGFPVSTLSIWFITYCGVQLIKERERILAMEEEKSDKPKAE", "length": 503, "header": "tr|A0A8V1ABQ8-1|A0A8V1ABQ8_CHICK Isoform 1 of Hedgehog acyltransferase-like OS=Gallus gallus OX=9031 GN=HHATL PE=3 SV=1 CANONICAL=A0A8V1ABQ8-1" }, "isoforms": [ { "isoform_ac": "A0A8V1ABQ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABQ8/entry#A0A8V1ABQ8-1", "sequence": { "sequence": "MGVKAMLPSHELGFYALVVTCAVLYSSSGIFEASRDSMNRKAFRDGIKPGWHYFGRKMDVADFEWVMWFTSFRNVIIFTLSGHVLFAKVCSMTVPQHRAVVYMLYGMLAVLGSMGLAYLMIILSHCLILYSVALSKQKWLCYVAGLCCLASIKLEPFSSWQSGFVTGAFDLQDVLFYGGSGFTIMRCMSFALESSERQEGIFSIFDLLKYNFYLPFFFFGPVMTFDQFHSQVSTRDLRRKEDEMRNIRVHALLHVGAIIAVDIFFHFFYILTLPSDLKFVNRLSDWALAGLAYSNLVYDWVKAAVMFGVINTIARLDHLDPPQPPKCITMLYVFAETHFDRGINDWLCKYVYDHIGENHDNVMKELMATIATFAVTTLWLGPCEIVYIWSVFNCFGLNFELWVQKFFQWEPLSKLEAKMSEATSRRIRAVFGAANFWAIVLYNILALNSLEFALLVTRRLLVTGFPVSTLSIWFITYCGVQLIKERERILAMEEEKSDKPKAE", "length": 503, "header": "tr|A0A8V1ABQ8-1|A0A8V1ABQ8_CHICK Isoform 1 of Hedgehog acyltransferase-like OS=Gallus gallus OX=9031 GN=HHATL PE=3 SV=1 CANONICAL=A0A8V1ABQ8-1" }, "locus": { "chromosome": "2", "start_pos": 2067163, "end_pos": 2056429, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066394.1", "url": "https://www.ensembl.org/id/ENSGALT00010066394.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040660.1", "url": "https://www.ensembl.org/id/ENSGALP00010040660.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:420391", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420391", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D4A9P9-1", "protein_name": "Hedgehog acyltransferase-like", "gene_name": "Hhatl", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGIKTALPAAELGLYSLVLSGALAYAGRGLLEASQDGAHRKAFRESVRPGWEYLGRKMDVADFEWVMWFTNFRNIIVFALSGHVLFAKLCTMVAPQLRSWMYAVYGVLAVVGTMGPWYLLLLLGHCVVLYVASLLGQRWLCLALGLASLASFKMDPGISWQSGFVTGTFDLQDVLFHGGSGFTVLRCTSFALESCAHPDRRYSLADLLKYNFYLPFFFFGPIMTFDRFQAQVSQEPVRPEGELWRIQTQAGLSAAAIVAVDIFFHFFYILTIPSDLKFASRLPDSALAGLAYSNLVYDWVKAAVLFGVVNTVARLDHLDPPQPPKCITALYVFGETHFDRGINDWLCKYVYDHIGGDHSAVIPELAASVATFVITTLWLGPCDIVYLWSVLNCFGLNFELWAQKLAEHGPLAQIEARLSEQMSRRVRALCGAVNFWAIIMYNLVSLNSLEFTELVARRLILTGFPQTTLAVLFVTYCGVQLVKERERSLALEEEQRQDKEKLE", "length": 503 }, "evidence": [ { "id": "A0A8V1ABQ8", "url": "https://omabrowser.org/oma/group/A0A8V1ABQ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1SRF0-1", "protein_name": "Hedgehog acyltransferase like", "gene_name": "HHATL", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGIKTALPAAEVGLYSLVLSGALAYAGRGLLEASQDGAHRKAFRESVRPGWEYIGRKMDVADFEWVMWFTSFRNVIVFALSGHVLFAKLCTMVAPQLRSWMYAVYGALAVVGTMGPWYLLLLLGHCVGLYMVSLLGQPWLCLGLGLASLASFKLDPLISWQSGFVTGTFDLQEVLFHGGSGFTVLRCTSFALESCAHPDRRYSLADLLKYNFYLPFFFFGPIMTFDRFHAQVSQVEPVRREGELWRIRAQAGLSVVAIVAVDIFFHFFYILTIPSDLKFANRLPDSALAGLAYSNLVYDWVKAAVLFGVVNTVARLDHLDPPQPPKCITALYVFAETHFDRGINDWLCKYVYDHIGGEHSSVIPELGATVATFAITTLWLGPCDIVYLWSCLNCFGLNFELWVQKLAEWGPLAHIEASLSEQMSRRVRAIFGAMNFWAIIMYNLVSLNSREFTELVAQRLLLRGFPQTTLAVLFVTYCGVQLVKERERTLALEEEQKQDKEKPE", "length": 504 }, "evidence": [ { "id": "A0A8V1ABQ8", "url": "https://omabrowser.org/oma/group/A0A8V1ABQ8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q9D1G3-1", "protein_name": "Protein-cysteine N-palmitoyltransferase HHAT-like protein", "gene_name": "Hhatl", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGIKTALPAAELGLYSLVLSGALAYAGRGLLEASQDGAHRKAFRESVRPGWEYLGRKMDVADFEWVMWFTNFRNVIVFALSGHVLFAKLCTMVAPQLRSWMYAVYGVLAVVGTMGPWYLLLLLGHCMVLYVASLLGQRWLCLALGLASLASFKVDPGISWQSGFVTGTFDLQDVLFHGGSSFTVLRCTSFALESCAHPDRRYSLADLLKYNFYLPFFFFGPIMTFDRFHAQVSQEPVRPEGELWHIQAQAGLSAAAIVAVDVFFHFFYILTIPSDLKFASRLPDSALAGLAYSNLVYDWVKAAVLFGVVNTVARLDHLDPPQPPKCITALYVFGETHFDRGINDWLCKYVYDHIGGDHSTVIPELAASVATFVVTTLWLGPCDIVYLWSVLNCFGLNFELWVQKLAERGPLAQIEARLSEQMSRRVRALCGAVNFWAIIMYNLVSLNSLEFTELVARRLILTGFPQTTLAVLFVTYCGVQLVKERERSLALEEEQRQDREKLE", "length": 503 }, "evidence": [ { "id": "A0A8V1ABQ8", "url": "https://omabrowser.org/oma/group/A0A8V1ABQ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9HCP6-1", "protein_name": "Protein-cysteine N-palmitoyltransferase HHAT-like protein", "gene_name": "HHATL", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGIKTALPAAELGLYSLVLSGALAYAGRGLLEASQDGAHRKAFRESVRPGWEYIGRKMDVADFEWVMWFTSFRNVIIFALSGHVLFAKLCTMVAPKLRSWMYAVYGALAVMGTMGPWYLLLLLGHCVGLYVASLLGQPWLCLGLGLASLASFKMDPLISWQSGFVTGTFDLQEVLFHGGSSFTVLRCTSFALESCAHPDRHYSLADLLKYNFYLPFFFFGPIMTFDRFHAQVSQVEPVRREGELWHIRAQAGLSVVAIMAVDIFFHFFYILTIPSDLKFANRLPDSALAGLAYSNLVYDWVKAAVLFGVVNTVACLDHLDPPQPPKCITALYVFAETHFDRGINDWLCKYVYNHIGGEHSAVIPELAATVATFAITTLWLGPCDIVYLWSFLNCFGLNFELWMQKLAEWGPLARIEASLSVQMSRRVRALFGAMNFWAIIMYNLVSLNSLKFTELVARRLLLTGFPQTTLSILFVTYCGVQLVKERERTLALEEEQKQDKEKPE", "length": 504 }, "evidence": [ { "id": "A0A8V1ABQ8", "url": "https://omabrowser.org/oma/group/A0A8V1ABQ8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABQ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABQ8" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABQ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABQ8" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABQ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABQ8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of protein modification process", "id": "GO:0031399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031399", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABQ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABQ8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1ABR3-1", "uniprot_ac": "A0A8V1ABR3", "uniprot_id": "A0A8V1ABR3_CHICK", "mass": { "chemical_mass": 114192.0, "monoisotopic_mass": 114192.0 }, "refseq": {}, "gene_names": [ { "name": "CNTN2", "type": "recommended", "evidence": [ { "id": "A0A8V1ABR3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR3" } ] } ], "protein_names": [ { "name": "Contactin-2", "type": "recommended", "evidence": [ { "id": "A0A8V1ABR3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR3/entry#names_and_taxonomy" } ] }, { "name": "Axonin-1", "type": "synonym", "evidence": [ { "id": "A0A8V1ABR3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABR3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CNTN2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR3", "locus": { "chromosome": "26", "start_pos": 2039377, "end_pos": 2015205, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027385", "url": "https://www.ensembl.org/id/ENSGALG00010027385" } ] } } ], "crossref": [ { "id": "A0A8V1ABR3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1ABR3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000000653", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000000653", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00063", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00063", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd04968", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04968", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd04969", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04969", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd05727", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05727", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd05728", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05728", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd05850", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05850", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd05854", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05854", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "419825", "url": "https://www.ncbi.nlm.nih.gov/gene/419825", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013098", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013098", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047102", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047102", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:419825", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419825", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MPDANPR", "url": "https://omabrowser.org/oma/group/MPDANPR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ABR3", "url": "https://www.orthodb.org/?gene=A0A8V1ABR3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NSJ1", "url": "https://www.orthodb.org/?gene=F1NSJ1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR44170", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44170", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR44170:SF28", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44170:SF28", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00041", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00041", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07679", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07679", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13927", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13927", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1ABR3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ABR3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NSJ1", "url": "https://www.uniprot.org/uniprotkb/F1NSJ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NSJ1-1", "url": "https://www.uniprot.org/uniprotkb/F1NSJ1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "FLASAALVCTQLQAVFPSLAVWCQAQSGMRSYGPVFEEQPAHTLFPEGSAEEKVTLTCRARANPPATYRWKMNGTELKMGPDSRYRLVAGDLVISNPVKAKDAGSYQCVATNARGTVVSREASLRFGFLQEFSAEERDPVKITEGWGVMFTCSPPPHYPALSYRWLLNEFPNFIPADGRRFVSQTTGNLYIAKTEASDLGNYSCFATSHIDFITKSVFSKFSQLSLAAEDARQYAPSIKARFPADTYALTGQMVTLECFAFGNPVPQIKWRKLDGSQTSKWLSSEPLLHIQNVDFEDEGTYECEAENIKGRDTYQGRIIIHAQPDWLDVITDTEADIGSDLRWSCVASGKPRPAVRWLRDGQPLASQNRIEVSGGELRFSKLVLEDSGMYQCVAENKHGTVYASAELTVQALAPDFRLNPVKRLIPAARSGKVIIPCQPRAAPKATVLWTKGTELLTNSSRVTITADGTLILQNISKSDEGKYTCFAENFMGKANSTGILSVRDATKITLAPSSADINVGENLTLQCHASHDPTMDLTFTWSLDDFPIDLDKSEGHYRRASVKEAVGDLAIVNAQLKHSGRYTCTAQTVVDSTSESATLTVRGPPGPPGGVVVRDIGDTTVQLSWSRGFDNHSPIARYSIEARTLLSNKWKQMRTNPVNIEGNAETAQVVNLIPWMDYEFRVLASNILGVGEPSLPSSKIRTKEAEAPTCRKRRLACSKPWPGQLVFSLSPTLRDYQNGDGFGYILSFRKKGTQGWLTARVPHAESLHYVYRNESIGPYTPFEVKIKAYNRKGEGPESLTAIVYSAEEEPKVAPFRVTAKAVLSSEMDVSWEPVEQGDMTGVLLGYEIRYWKDGDKEEAADRVRTAGLVTSAHVTGLNPNTKYHVSVRAYNRAGAGPPSPSTNITTTKPPPRRPPGNISWTLTGSTVTIKWDPVVAQADESAVTGYKMLYRQDSHSAPTLYLASKSRIDIPVPEDFTHAFVQIRVTGPGGDGTPAEVHIVRNSGTSMMVEDSVTRPVPHAAIITTNSLAMVALIRYLEL", "length": 1039, "header": "tr|A0A8V1ABR3-1|A0A8V1ABR3_CHICK Isoform 1 of Contactin-2 OS=Gallus gallus OX=9031 GN=CNTN2 PE=3 SV=1 CANONICAL=A0A8V1ABR3-1" }, "isoforms": [ { "isoform_ac": "A0A8V1ABR3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR3/entry#A0A8V1ABR3-1", "sequence": { "sequence": "FLASAALVCTQLQAVFPSLAVWCQAQSGMRSYGPVFEEQPAHTLFPEGSAEEKVTLTCRARANPPATYRWKMNGTELKMGPDSRYRLVAGDLVISNPVKAKDAGSYQCVATNARGTVVSREASLRFGFLQEFSAEERDPVKITEGWGVMFTCSPPPHYPALSYRWLLNEFPNFIPADGRRFVSQTTGNLYIAKTEASDLGNYSCFATSHIDFITKSVFSKFSQLSLAAEDARQYAPSIKARFPADTYALTGQMVTLECFAFGNPVPQIKWRKLDGSQTSKWLSSEPLLHIQNVDFEDEGTYECEAENIKGRDTYQGRIIIHAQPDWLDVITDTEADIGSDLRWSCVASGKPRPAVRWLRDGQPLASQNRIEVSGGELRFSKLVLEDSGMYQCVAENKHGTVYASAELTVQALAPDFRLNPVKRLIPAARSGKVIIPCQPRAAPKATVLWTKGTELLTNSSRVTITADGTLILQNISKSDEGKYTCFAENFMGKANSTGILSVRDATKITLAPSSADINVGENLTLQCHASHDPTMDLTFTWSLDDFPIDLDKSEGHYRRASVKEAVGDLAIVNAQLKHSGRYTCTAQTVVDSTSESATLTVRGPPGPPGGVVVRDIGDTTVQLSWSRGFDNHSPIARYSIEARTLLSNKWKQMRTNPVNIEGNAETAQVVNLIPWMDYEFRVLASNILGVGEPSLPSSKIRTKEAEAPTCRKRRLACSKPWPGQLVFSLSPTLRDYQNGDGFGYILSFRKKGTQGWLTARVPHAESLHYVYRNESIGPYTPFEVKIKAYNRKGEGPESLTAIVYSAEEEPKVAPFRVTAKAVLSSEMDVSWEPVEQGDMTGVLLGYEIRYWKDGDKEEAADRVRTAGLVTSAHVTGLNPNTKYHVSVRAYNRAGAGPPSPSTNITTTKPPPRRPPGNISWTLTGSTVTIKWDPVVAQADESAVTGYKMLYRQDSHSAPTLYLASKSRIDIPVPEDFTHAFVQIRVTGPGGDGTPAEVHIVRNSGTSMMVEDSVTRPVPHAAIITTNSLAMVALIRYLEL", "length": 1039, "header": "tr|A0A8V1ABR3-1|A0A8V1ABR3_CHICK Isoform 1 of Contactin-2 OS=Gallus gallus OX=9031 GN=CNTN2 PE=3 SV=1 CANONICAL=A0A8V1ABR3-1" }, "locus": { "chromosome": "26", "start_pos": 2038105, "end_pos": 2027310, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066400.1", "url": "https://www.ensembl.org/id/ENSGALT00010066400.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040665.1", "url": "https://www.ensembl.org/id/ENSGALP00010040665.1" } ] } }, { "isoform_ac": "F1NSJ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR3/entry#F1NSJ1-1", "sequence": { "sequence": "MGGTAAFICTSLAVIICVVWCQAQSGMRSYGPVFEEQPAHTLFPEGSAEEKVTLTCRARANPPATYRWKMNGTELKMGPDSRYRLVAGDLVISNPVKAKDAGSYQCVATNARGTVVSREASLRFGFLQEFSAEERDPVKITEGWGVMFTCSPPPHYPALSYRWLLNEFPNFIPADGRRFVSQTTGNLYIAKTEASDLGNYSCFATSHIDFITKSVFSKFSQLSLAAEDARQYAPSIKARFPADTYALTGQMVTLECFAFGNPVPQIKWRKLDGSQTSKWLSSEPLLHIQNVDFEDEGTYECEAENIKGRDTYQGRIIIHAQPDWLDVITDTEADIGSDLRWSCVASGKPRPAVRWLRDGQPLASQNRIEVSGGELRFSKLVLEDSGMYQCVAENKHGTVYASAELTVQALAPDFRLNPVKRLIPAARSGKVIIPCQPRAAPKATVLWTKGTELLTNSSRVTITADGTLILQNISKSDEGKYTCFAENFMGKANSTGILSVRDATKITLAPSSADINVGENLTLQCHASHDPTMDLTFTWSLDDFPIDLDKSEGHYRRASVKEAVGDLAIVNAQLKHSGRYTCTAQTVVDSTSESATLTVRGPPGPPGGVVVRDIGDTTVQLSWSRGFDNHSPIARYSIEARTLLSNKWKQMRTNPVNIEGNAETAQVVNLIPWMDYEFRVLASNILGVGEPSLPSSKIRTKEAAPTVAPSGLGGGGGAPNELIINWTPTLRDYQNGDGFGYILSFRKKGTQGWLTARVPHAESLHYVYRNESIGPYTPFEVKIKAYNRKGEGPESLTAIVYSAEEEPKVAPFRVTAKAVLSSEMDVSWEPVEQGDMTGVLLGYEIRYWKDGDKEEAADRVRTAGLVTSAHVTGLNPNTKYHVSVRAYNRAGAGPPSPSTNITTTKPPPRRPPGNISWTLTGSTVTIKWDPVVAQADESAVTGYKMLYRQDSHSAPTLYLASKSRIDIPVPEDFTHAFVQIRVTGPGGDGTPAEVHIVRNSGTSMMVEDSVTRPVPHAAIITTNSLAMVALIRYLEL", "length": 1036, "header": "tr|F1NSJ1-1|A0A8V1ABR3_CHICK Computationally mapped isoform of Contactin-2 OS=Gallus gallus OX=9031 GN=CNTN2 PE=3 SV=1 CANONICAL=A0A8V1ABR3-1" }, "locus": { "chromosome": "26", "start_pos": 2038105, "end_pos": 2024464, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066403.1", "url": "https://www.ensembl.org/id/ENSGALT00010066403.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040669.1", "url": "https://www.ensembl.org/id/ENSGALP00010040669.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:419825", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419825", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "E1BPC9-1", "protein_name": "Contactin-2", "gene_name": "CNTN2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGTPLGRKAHLLMLVAVALVSTPAWSSAWGSPATFGPVFEEQPLGLLFPEESTEEKVTLACRARASPPATYRWKMNGTEMKLEPGSRQQLVGGNLVIMNPSKAQDAGVYQCLASNPVGTVVSREAVLRFGFLQEFSKEERDPVKTHEGWGVMLPCNPPAHYPGLSYRWLLNEFPNFIPTDGRHFVSQTTGNLYIARTNASDLGNYSCLATSHMDFSTKSVFSKFAQLNLAAEDTRLFAPSIKARFPAETYALVGQQVTLECFAFGNPVPRIKWRKVDGSLSPQWATAEPTLQIPSVGFEDEGTYECEAENTKGRDTVQGRIIVQAQPEWLRVISDREADIGSDLHWACAAAGKPRPAVRWLRNGEPLTSQARVEVLAGDLRFSKLSLEDSGMYQCVAENKHGTIYASAELAVQALAPDFRLNPVRRLIPAARGGEVVIPCQPRAAPKAVVLWSKGTEILVNSSRVTVTPDGTLIIRNVSRSDEGKYTCFAENFMGKANSTGTLSVRDATKITLAPSSADINLGDNLTLQCHASHDPTMDLTFVWTLDDFPIDFDKPGGHYQRASVKETVGDLTILNAQLRHGGKYTCTAQTVVDSASKEATVLVRGPPGAPGGVVVRDISDTSVQLSWSRGFDNHSPIAKYTLQARTLPSGKWKQVRTNPTNIEGNAETAQVLGLTPWMDYEFRVLASNILGTGEPSGPSSKIQTKEAAPSVAPSGLSGGGGAPGELTVTWTPMSREYQHGGGFGYLVSFRRQGGTSWQTARVPGADAQYFVYSNDSIRPYTPFEVKIRSYNRRGDGPESLVAVVYSAEEEPRVAPPKVWAKAVSSSEMNVSWEPVQQDMNGILLGYEIRYWKAGAKAAAAERVRTAGLDTSALVTGLHASTKYHVTVRAYNRAGTGPASPSANATTMKPPPRRPPGNISWTFSSSSLSIKWDPVVPLGNESAVTGYKMLYQNDLHPTPTLHLTSKNWIEITVPEDIGHALVQIRTTGPGGDGVPAEVHIVRNGGTSMMVENSAVCPAPHPDAALTHSVAALILLGYLQL", "length": 1040 }, "evidence": [ { "id": "A0A8V1ABR3", "url": "https://omabrowser.org/oma/group/A0A8V1ABR3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P22063-1", "protein_name": "Contactin-2", "gene_name": "Cntn2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGTHARKKASLLLLVLATVALVSSPGWSFAQGTPATFGPIFEEQPIGLLFPEESAEDQVTLACRARASPPATYRWKMNGTDMNLEPGSRHQLMGGNLVIMSPTKTQDAGVYQCLASNPVGTVVSKEAVLRFGFLQEFSKEERDPVKTHEGWGVMLPCNPPAHYPGLSYRWLLNEFPNFIPTDGRHFVSQTTGNLYIARTNASDLGNYSCLATSHMDFSTKSVFSKFAQLNLAAEDPRLFAPSIKARFPPETYALVGQQVTLECFAFGNPVPRIKWRKVDGSLSPQWATAEPTLQIPSVSFEDEGTYECEAENSKGRDTVQGRIIVQAQPEWLKVISDTEADIGSNLRWGCAAAGKPRPMVRWLRNGEPLASQNRVEVLAGDLRFSKLSLEDSGMYQCVAENKHGTIYASAELAVQALAPDFRQNPVRRLIPAARGGEISILCQPRAAPKATILWSKGTEILGNSTRVTVTSDGTLIIRNISRSDEGKYTCFAENFMGKANSTGILSVRDATKITLAPSSADINVGDNLTLQCHASHDPTMDLTFTWTLDDFPIDFDKPGGHYRRASAKETIGDLTILNAHVRHGGKYTCMAQTVVDGTSKEATVLVRGPPGPPGGVVVRDIGDTTVQLSWSRGFDNHSPIAKYTLQARTPPSGKWKQVRTNPVNIEGNAETAQVLGLMPWMDYEFRVSASNILGTGEPSGPSSKIRTKEAVPSVAPSGLSGGGGAPGELIINWTPVSREYQNGDGFGYLLSFRRQGSSSWQTARVPGADAQYFVYGNDSIQPYTPFEVKIRSYNRRGDGPESLTALVYSAEEEPRVAPAKVWAKGSSSSEMNVSWEPVLQDMNGILLGYEIRYWKAGDNEAAADRVRTAGLDTSARVTGLNPNTKYHVTVRAYNRAGTGPASPSADAMTVKPPPRRPPGNISWTFSSSSLSLKWDPVVPLRNESTVTGYKMLYQNDLHPTPTLHLTSKNWIEIPVPEDIGHALVQIRTTGPGGDGIPAEVHIVRNGGTSMMVESAAARPAHPGPAFSCMVILMLAGYQKL", "length": 1040 }, "evidence": [ { "id": "A0A8V1ABR3", "url": "https://omabrowser.org/oma/group/A0A8V1ABR3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q61330-1", "protein_name": "Contactin-2", "gene_name": "Cntn2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGAPARKRASLLLLLLATMALVSSPGWSFSQGTPATFGPVFEEQPVGLLFPEESAEDQVTLACRARASPPATYRWKMNGTEMNLEPGSRHQLMGGNLVIMSPTKAQDAGVYQCLASNPVGTVVSKEAVLRFGFLQEFSKEERDPVKTHEGWGVMLPCNPPAHYPGLSYRWLLNEFPNFIPTDGRHFVSQTTGNLYIARTNASDLGNYSCLATSHLDFSTKSVFSKFAQLNLAAEDPRLFAPSIKARFPPETYALVGQQVTLECFAFGNPVPRIKWRKVDGSLSPQWGTAEPTLQIPSVSFEDEGTYECEAENSKGRDTVQGRIIVQAQPEWLKVISDTEADIGSNLRWGCAAAGKPRPMVRWLRNGEPLASQNRVEVLAGDLRFSKLNLEDSGMYQCVAENKHGTIYASAELAVQALAPDFRQNPVRRLIPAARGGEISIPCQPRAAPKATILWSKGTEILGNSTRVTVTLDGTLIIRNISRSDEGKYTCFAENFMGKANSTGILSVRDATKITLAPSSADINVGDNLTLQCHASHDPTMDLTFTWTLDDFPVDFDKPGGHYRRASVKETIGDLTILNAQLRHGGTYTCMAQTVVDGASKEATVLVRGPPGPPGGVVVRDIGDTTVQLSWSRGFDNHSPIAKYTLQARTPPSGKWKQVRTNPVNIEGNAETAQVLGLMPWMDYEFRVSASNILGTGEPSGPSSRIRTKEAVPSVAPSGLSGGGGAPGELTINWTPMSREYQNGDGFGYLLSFRRQGSSSWQTARVPGADTQYFVYSNDSIHPYTPFEVKIRSYNRRGDGPESLTAIVYSAEEEPKVAPAKVWAKGSSSSEMNVSWEPVLQDMNGILLGYEIRYWKAGDKEAAADRVRTAGLDSSARVTGLYPNTKYHVTVRAYNRAGTGPASPSADAMTMKPPPRRPPGNISWTFSSSSLSLKWDPVVPLRNESTVTGYKMLYQNDLQPTPMLHLTSKNWIEIPVPEDIGHALVQIRTTGPGGDGIPAEVHIVRNGGTSMMVESSAVRPAHPGPVFSCMVILMLAGCQRL", "length": 1040 }, "evidence": [ { "id": "A0A8V1ABR3", "url": "https://omabrowser.org/oma/group/A0A8V1ABR3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 9, "go_terms": [ { "name": "cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABR3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR3" } ], "pmid": "" }, { "name": "neuronal cell body", "id": "GO:0043025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043025", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABR3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR3" } ], "pmid": "" }, { "name": "myelin sheath", "id": "GO:0043209", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043209", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABR3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR3" } ], "pmid": "" }, { "name": "postsynaptic membrane", "id": "GO:0045211", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045211", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABR3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR3" } ], "pmid": "" }, { "name": "node of Ranvier", "id": "GO:0033268", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033268", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABR3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR3" } ], "pmid": "" }, { "name": "axon initial segment", "id": "GO:0043194", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043194", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABR3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR3" } ], "pmid": "" }, { "name": "juxtaparanode region of axon", "id": "GO:0044224", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044224", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABR3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR3" } ], "pmid": "" }, { "name": "side of membrane", "id": "GO:0098552", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098552", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABR3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR3" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABR3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "carbohydrate binding", "id": "GO:0030246", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030246", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABR3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR3" } ], "pmid": "" }, { "name": "cell adhesion mediator activity", "id": "GO:0098631", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098631", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABR3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "fat cell differentiation", "id": "GO:0045444", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045444", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABR3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR3" } ], "pmid": "" }, { "name": "regulation of cell morphogenesis", "id": "GO:0022604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022604", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABR3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR3" } ], "pmid": "" }, { "name": "clustering of voltage-gated potassium channels", "id": "GO:0045163", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045163", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABR3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR3" } ], "pmid": "" }, { "name": "establishment of protein localization to juxtaparanode region of axon", "id": "GO:0071206", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071206", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABR3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR3" } ], "pmid": "" }, { "name": "presynaptic membrane organization", "id": "GO:0097090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097090", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABR3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR3" } ], "pmid": "" }, { "name": "reduction of food intake in response to dietary excess", "id": "GO:0002023", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002023", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABR3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR3" } ], "pmid": "" }, { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABR3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 201, "end_pos": 203, "annotation": "n_glycosylation_sequon" }, { "start_pos": 458, "end_pos": 460, "annotation": "n_glycosylation_sequon" }, { "start_pos": 474, "end_pos": 476, "annotation": "n_glycosylation_sequon" }, { "start_pos": 495, "end_pos": 497, "annotation": "n_glycosylation_sequon" }, { "start_pos": 522, "end_pos": 524, "annotation": "n_glycosylation_sequon" }, { "start_pos": 631, "end_pos": 633, "annotation": "n_glycosylation_sequon" }, { "start_pos": 73, "end_pos": 75, "annotation": "n_glycosylation_sequon" }, { "start_pos": 773, "end_pos": 775, "annotation": "n_glycosylation_sequon" }, { "start_pos": 903, "end_pos": 905, "annotation": "n_glycosylation_sequon" }, { "start_pos": 917, "end_pos": 919, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], 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"ENSGALP00010043439.1", "url": "https://www.ensembl.org/id/ENSGALP00010043439.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABR7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABR7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR7" } ], "pmid": "" }, { "name": "cilium", "id": "GO:0005929", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005929", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABR7", 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"categories": [ "Protein Classification" ] }, { "id": "IPR002575", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002575", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006439", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006439", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011945", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011945", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023198", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023198", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023214", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023214", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036412", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036412", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041726", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041726", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052898", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052898", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ABR9", "url": "https://www.orthodb.org/?gene=A0A8V1ABR9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47829", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47829", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47829:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47829:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00702", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00702", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01636", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01636", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1ABR9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ABR9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MYLSSAARTPLLRWAGILQSPGLWLRRQSGWSPYGAVIFDASGVLLPSPQHTAADWEARNCIPAGTVQQALLSGGENSPSLKYTRGELTTVEFLEELGQQCFEIANIRVPVNSFLSKLIRNEMIKQLPIMAEAIQCIRAEGLKTALLSNSFRLPNGESFLPLDQKHFDVIVEAYREGKCKPDPRIYKLCLERLDVQPQESIFLDNSSQNLKTAAQLGIKTVKVDDLEVAFKELETYLGFPLQGFVPYTRSVGPTTEIPKDRLQKYLENVFSDQATGPLTLRQFGCGQSTRTYFVKFGDRSLVLKKELPDSLLPSGPAVGREYRVLKALSEAGVPVPTVLALCEDRSILGTPFYLMEHCAGHVYRDASLPTLLPSQRRAIYAAMSEVLSKIHSTDLRAAKLEDSRDHGNYIQQQVDTWTKQYRATETHVIPAMERLIEWLPLHFPESQKTTAVHGDFRLDNLIFHPRRPEVLAVLGWKFSILGDPISDLANNCMAYFLPPQFDSMKGLAKYDLRHLGVPTAEEYCQKYCGHMGMELPENWNFYMAFAFFRLAAMLQGLHKCSVAGEEPNHTARRKSCLEHAELVADLAWDFAIKEGFRVFNSLSIAKPFAQHYSTWARQGPFLSRSYSTWTRPETVPVPEVPMITSISSLLGMAQGIYCKLARNLDVQWSFLISQPRRTPRPVLEKKVLVLPPQAATTNNDGVSRGWPGWSFSAHRCQSSACSLLSPSRAVPADSPVGKQLPAQC", "length": 744, "header": "tr|A0A8V1ABR9-1|A0A8V1ABR9_CHICK Isoform 1 of Aminoglycoside phosphotransferase domain-containing protein OS=Gallus gallus OX=9031 GN=LOC107057078 PE=4 SV=1 CANONICAL=A0A8V1ABR9-1" }, "isoforms": [ { "isoform_ac": "A0A8V1ABR9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR9/entry#A0A8V1ABR9-1", "sequence": { "sequence": "MYLSSAARTPLLRWAGILQSPGLWLRRQSGWSPYGAVIFDASGVLLPSPQHTAADWEARNCIPAGTVQQALLSGGENSPSLKYTRGELTTVEFLEELGQQCFEIANIRVPVNSFLSKLIRNEMIKQLPIMAEAIQCIRAEGLKTALLSNSFRLPNGESFLPLDQKHFDVIVEAYREGKCKPDPRIYKLCLERLDVQPQESIFLDNSSQNLKTAAQLGIKTVKVDDLEVAFKELETYLGFPLQGFVPYTRSVGPTTEIPKDRLQKYLENVFSDQATGPLTLRQFGCGQSTRTYFVKFGDRSLVLKKELPDSLLPSGPAVGREYRVLKALSEAGVPVPTVLALCEDRSILGTPFYLMEHCAGHVYRDASLPTLLPSQRRAIYAAMSEVLSKIHSTDLRAAKLEDSRDHGNYIQQQVDTWTKQYRATETHVIPAMERLIEWLPLHFPESQKTTAVHGDFRLDNLIFHPRRPEVLAVLGWKFSILGDPISDLANNCMAYFLPPQFDSMKGLAKYDLRHLGVPTAEEYCQKYCGHMGMELPENWNFYMAFAFFRLAAMLQGLHKCSVAGEEPNHTARRKSCLEHAELVADLAWDFAIKEGFRVFNSLSIAKPFAQHYSTWARQGPFLSRSYSTWTRPETVPVPEVPMITSISSLLGMAQGIYCKLARNLDVQWSFLISQPRRTPRPVLEKKVLVLPPQAATTNNDGVSRGWPGWSFSAHRCQSSACSLLSPSRAVPADSPVGKQLPAQC", "length": 744, "header": "tr|A0A8V1ABR9-1|A0A8V1ABR9_CHICK Isoform 1 of Aminoglycoside phosphotransferase domain-containing protein OS=Gallus gallus OX=9031 GN=LOC107057078 PE=4 SV=1 CANONICAL=A0A8V1ABR9-1" }, "locus": { "chromosome": "15", "start_pos": 6220310, "end_pos": 6211221, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010062992.1", "url": "https://www.ensembl.org/id/ENSGALT00010062992.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038898.1", "url": "https://www.ensembl.org/id/ENSGALP00010038898.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 254, "start_aa": "Thr", "end_pos": 254, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr254", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 205, "end_pos": 207, "annotation": "n_glycosylation_sequon" }, { "start_pos": 568, "end_pos": 570, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1ABR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR9" }, { "id": "PF01636", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01636" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Aminoglycoside phosphotransferase", "eco_id": "ECO_0000259", "start_pos": 279, "end_pos": 496, "start_aa": "Thr", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 254 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 205, "end_pos": 207 }, { "start_pos": 568, "end_pos": 570 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1ABT2-1", "uniprot_ac": "A0A8V1ABT2", "uniprot_id": "A0A8V1ABT2_CHICK", "mass": { "chemical_mass": 59107.0, "monoisotopic_mass": 59107.0 }, "refseq": {}, "gene_names": [ { "name": "TDRKH", "type": "recommended", "evidence": [ { "id": "A0A8V1ABT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABT2" } ] } ], "protein_names": [ { "name": "Tudor and KH domain containing", "type": "synonym", "evidence": [ { "id": "A0A8V1ABT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABT2/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABT2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABT2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TDRKH", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABT2", "locus": {} } ], "crossref": [ { "id": "A0A8V1ABT2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1ABT2", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd20412", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20412", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR002999", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002999", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004088", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004088", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035437", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035437", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036612", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036612", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047380", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047380", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050621", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050621", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ABT2", "url": "https://www.orthodb.org/?gene=A0A8V1ABT2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22948", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22948", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22948:SF18", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22948:SF18", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00013", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00013", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00567", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00567", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1ABT2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABT2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ABT2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABT2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPSERSGWAGLSGLQKVAVLLGLPAGATVLYILHVPTVGAEELRAELRVPRAAVRAIIGRKGTTIRRVRAQETGARIDLEGEDDGEERLLLIWGSPSQVCRAKAAVHQIVVESTPVSEQLHVPQRAVGRIIGHGGETVRSICRSSGAQVQCQHQAEAMLAPTRLIQISGTQREVDAAKKLIMEKLVEDAVFRQELAQTTVLRSHRKEPLGSRREALLLPDREHGAGNGGPLRGGAAMEEPPMLLGCPMGSEGFVALVCSLLPHSGSSSPTIHPLCLSPAGSYPAVPSPDFSFHADEHLEVYVSAAENPNHFWIQIIGERSLQLDKLISEMTQHYEGSDCAVQAGDIVAAPYTDSSNWYRARVLGTLENGNLDLYYVDFGDNGEAPREALRVLRSDFLSLPFQAIECSLAGIVPVGEQWDEAALDAFERLTYCAQWKPLVAKISSYTQAGLCTWPRIALFDVHHGESLDIGAELVRLGHAALQPHEEEKEGGGFPLPDMVCTSLESILSELPPSPSATPLTLSCISLLGEHCGADPNSSNVPRCEGACLG", "length": 549, "header": "tr|A0A8V1ABT2-1|A0A8V1ABT2_CHICK Isoform 1 of Tudor and KH domain containing OS=Gallus gallus OX=9031 GN=TDRKH PE=4 SV=1 CANONICAL=A0A8V1ABT2-1" }, "isoforms": [ { "isoform_ac": "A0A8V1ABT2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABT2/entry#A0A8V1ABT2-1", "sequence": { "sequence": "MPSERSGWAGLSGLQKVAVLLGLPAGATVLYILHVPTVGAEELRAELRVPRAAVRAIIGRKGTTIRRVRAQETGARIDLEGEDDGEERLLLIWGSPSQVCRAKAAVHQIVVESTPVSEQLHVPQRAVGRIIGHGGETVRSICRSSGAQVQCQHQAEAMLAPTRLIQISGTQREVDAAKKLIMEKLVEDAVFRQELAQTTVLRSHRKEPLGSRREALLLPDREHGAGNGGPLRGGAAMEEPPMLLGCPMGSEGFVALVCSLLPHSGSSSPTIHPLCLSPAGSYPAVPSPDFSFHADEHLEVYVSAAENPNHFWIQIIGERSLQLDKLISEMTQHYEGSDCAVQAGDIVAAPYTDSSNWYRARVLGTLENGNLDLYYVDFGDNGEAPREALRVLRSDFLSLPFQAIECSLAGIVPVGEQWDEAALDAFERLTYCAQWKPLVAKISSYTQAGLCTWPRIALFDVHHGESLDIGAELVRLGHAALQPHEEEKEGGGFPLPDMVCTSLESILSELPPSPSATPLTLSCISLLGEHCGADPNSSNVPRCEGACLG", "length": 549, "header": "tr|A0A8V1ABT2-1|A0A8V1ABT2_CHICK Isoform 1 of Tudor and KH domain containing OS=Gallus gallus OX=9031 GN=TDRKH PE=4 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"https://www.uniprot.org/uniprotkb/A0A8V1ABU0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "XAF1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABU0", "locus": {} } ], "crossref": [ { "id": "A0A8V1ABU0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1ABU0", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR003006", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003006", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003597", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003597", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013106", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013106", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050380", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050380", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR23411", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23411", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07654", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07654", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07686", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07686", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1ABU0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABU0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ABU0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABU0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJ65", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ65", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJ65-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ65-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALA3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALA3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALA3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALA3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLDCRISPYFTANTQILWPGRKVKAHGLDTWFTCTIEHAAGKYTATAFLVQGHEDREHQTPGQLHQGIAEQTRVSAVLAARTRLPRVRTALGKDVVLDCAFAADPRAAVAVRWALRKKGRHERYIATSGGRAEMFPQEPRGNASLLIRRVELSDEGTYICTVEAAALVLEQAIQLQITEKPTVTVNVNSLSLVEGEQQKLVCDVRNYYPADIHVQWLREPQSAGQLPDTVPNVLTSSHLRSSNGTYSFSRFFLLTATLRDNGHTYTCRVEHSSLQAPIRRSVTVAVREATSTTWLLLLLLLGLTGCLVASLHHLHQGYTQCYIHSNNEACSKVPRGAHPSRTQPRQCNAPCGDRGHAAPPAPTAPAAAAAEEPRGRVLHRGYRTRRCQGNIPAPHLPSPKSPKLWKETESVLRTVPFYPEKKSTSICI", "length": 428, "header": "tr|A0A8V1ABU0-1|A0A8V1ABU0_CHICK Isoform 1 of Ig-like domain-containing protein OS=Gallus gallus OX=9031 GN=XAF1 PE=4 SV=1 CANONICAL=A0A8V1ABU0-1" }, "isoforms": [ { "isoform_ac": "A0A8V1ABU0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABU0/entry#A0A8V1ABU0-1", "sequence": { "sequence": "MLDCRISPYFTANTQILWPGRKVKAHGLDTWFTCTIEHAAGKYTATAFLVQGHEDREHQTPGQLHQGIAEQTRVSAVLAARTRLPRVRTALGKDVVLDCAFAADPRAAVAVRWALRKKGRHERYIATSGGRAEMFPQEPRGNASLLIRRVELSDEGTYICTVEAAALVLEQAIQLQITEKPTVTVNVNSLSLVEGEQQKLVCDVRNYYPADIHVQWLREPQSAGQLPDTVPNVLTSSHLRSSNGTYSFSRFFLLTATLRDNGHTYTCRVEHSSLQAPIRRSVTVAVREATSTTWLLLLLLLGLTGCLVASLHHLHQGYTQCYIHSNNEACSKVPRGAHPSRTQPRQCNAPCGDRGHAAPPAPTAPAAAAAEEPRGRVLHRGYRTRRCQGNIPAPHLPSPKSPKLWKETESVLRTVPFYPEKKSTSICI", "length": 428, "header": "tr|A0A8V1ABU0-1|A0A8V1ABU0_CHICK Isoform 1 of Ig-like domain-containing protein OS=Gallus gallus OX=9031 GN=XAF1 PE=4 SV=1 CANONICAL=A0A8V1ABU0-1" }, "locus": { "chromosome": "19", "start_pos": 10057845, "end_pos": 10053523, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070772.1", "url": "https://www.ensembl.org/id/ENSGALT00010070772.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043463.1", "url": "https://www.ensembl.org/id/ENSGALP00010043463.1" } ] } }, { "isoform_ac": "A0A8V1AJ65-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABU0/entry#A0A8V1AJ65-1", "sequence": { "sequence": "MRISTCLTAGSALTLQPTLRFSGLGERSKPTAWTRGSLAPLSTQLGNTQPQPSLCKAMRTESTKLQDSFIRASQSRHAYQRAAVAVRWALRKKGRHERYIATSGGRAEMFPQEPRGNASLLIRRVELSDEGTYICTVEAAALVLEQAIQLQITEKPTVTVNVNSLSLVEGEQQKLVCDVRNYYPADIHVQWLREPQSAGQLPDTVPNVLTSSHLRSSNGTYSFSRFFLLTATLRDNGHTYTCRVEHSSLQAPIRRSVTVAVREATSTTWLLLLLLLGLTGCLVASLHHLHQVRSTTKPKPY", "length": 301, "header": "tr|A0A8V1AJ65-1|A0A8V1ABU0_CHICK Computationally mapped isoform of Ig-like domain-containing protein OS=Gallus gallus OX=9031 GN=XAF1 PE=4 SV=1 CANONICAL=A0A8V1ABU0-1" }, "locus": { "chromosome": "19", "start_pos": 10057859, "end_pos": 10054681, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070771.1", "url": "https://www.ensembl.org/id/ENSGALT00010070771.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043462.1", "url": "https://www.ensembl.org/id/ENSGALP00010043462.1" } ] } }, { "isoform_ac": "A0A8V1ALA3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABU0/entry#A0A8V1ALA3-1", "sequence": { "sequence": "MLDCRISPYFTANTQILWPGRKVKAHGLDTWFTCTIEHAAGKYTATAFLVQGHEDREHQTPGQLHQGIAEQTRVSAVLAARTRLPRVRTALGKDVVLDCAFAADPRAAVAVRWALRKKGRHERYIATSGGRAEMFPQEPRGNASLLIRRVELSDEGTYICTVEAAALVLEQAIQLQITEKPTVTVNVNSLSLVEGEQQKLVCDVRNYYPADIHVQWLREPQSAGQLPDTVPNVLTSSHLRSSNGTYSFSRFFLLTATLRDNGHTYTCRVEHSSLQAPIRRSVTVAVRGTEHCAGAVWALSHSSQGGEGRGQPSHPFLLSALPSVSLSRTNKQEAKQQKPAWSPPSFVPILLLLIHLQKQPPPPGCCCCCCWASLGALWPHSITSTK", "length": 386, "header": "tr|A0A8V1ALA3-1|A0A8V1ABU0_CHICK Computationally mapped isoform of Ig-like domain-containing protein OS=Gallus gallus OX=9031 GN=XAF1 PE=4 SV=1 CANONICAL=A0A8V1ABU0-1" }, "locus": { "chromosome": "19", "start_pos": 10057845, "end_pos": 10055006, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070770.1", "url": "https://www.ensembl.org/id/ENSGALT00010070770.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043461.1", "url": "https://www.ensembl.org/id/ENSGALP00010043461.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 283, "start_aa": "Thr", "end_pos": 283, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr283", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 363, "start_aa": "Thr", "end_pos": 363, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr363", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 142, "end_pos": 144, "annotation": "n_glycosylation_sequon" }, { "start_pos": 243, "end_pos": 245, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1ABU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABU0" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 72, "end_pos": 174, "start_aa": "Thr", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 283, 363 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 142, "end_pos": 144 }, { "start_pos": 243, "end_pos": 245 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1ABV0-1", "uniprot_ac": "A0A8V1ABV0", "uniprot_id": "A0A8V1ABV0_CHICK", "mass": { "chemical_mass": 99779.0, "monoisotopic_mass": 99779.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "A0A8V1ABV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABV0/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABV0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABV0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABV0", "locus": {} } ], "crossref": [ { "id": "A0A8V1ABV0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1ABV0", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021133", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021133", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045206", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045206", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048465", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048465", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055406", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055406", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055408", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055408", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR23120", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23120", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23120:SF42", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23120:SF42", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF21047", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21047", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23210", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23210", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23227", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23227", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1ABV0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABV0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ABV0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABV0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AEJ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEJ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AEJ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEJ2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEQRSPSCHQKAWPEKPMISQASRPQWGTDEVCEMQVPLGSGEGPSASDMSPQQEDPLSCIRACCMCRPQAEAQKLSFLASICTICEAALEDSGAHYRLCVCPLEVAQCIEELLQEEPAERLDTELWQQAMNAIAAMSRAWLLPEERKSSLLRACLGSVLRLPRHEDTQDRDAALYMETMEALHRLLQVLVGSAGTSVLMELQNILELLLPFTTCQLAAVEERAMACIARLLAFSNTCPLPEVCSCFTGAVVLRHQCTENQRFPVLGKLAGQLILCCTSTDEGTRDEAMKAVRQLFIFIASQRMWMWQKDPKKPQLRERWQTLFYEQVSQENNARKIFRMFLKYLQYPERVSIFLTAIESMTVPSLHSTELAAHMVDVLSAEVHFPPGQVQKIVKVIYSSLPSITAQPALESLGRALLVLASKYPREMVSSLLGCSPTCTSVTITMWKEMLSESLAVEKVLQELLRVLTNHSLYHMSTSTGDRPRVLALAAARILPEIIQLPLVLKEAEAIFPQLFLALLLQVSFTMELTLQEVEIFWEVHQQHHLTPIRAAVQSLKVLLCGVGLQKQMEAIEEQGGWDALLSTVTHLQGVQVVARVMRELPGALRDPIFHQLVELLSTKFCSWEMVAMVFLVEMLECVDLSEELHRVVSLFSTYLQSQSVGMQQLVLRGILQLSKRQDTARKMLGLLPCITEQLQDADSGARAMALPVLSSLLRLLERGKLSLVALELASNLPALFEDESGTVRQLSIHLFLDTLSFVEGREKRKMRKEVYRSLVPLYLHLHDEEESVAKASQKAFLGAARFLHWRRLEHLAEVAQFWQIGECMVCTFPHPRSGSGPLCADPVPFSLQLVERRKSAAQDYLGQSLLYLQSPQEPLRREAVRFIGEP", "length": 887, "header": "tr|A0A8V1ABV0-1|A0A8V1ABV0_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1ABV0-1" }, "isoforms": [ { "isoform_ac": "A0A8V1ABV0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABV0/entry#A0A8V1ABV0-1", "sequence": { "sequence": "MEQRSPSCHQKAWPEKPMISQASRPQWGTDEVCEMQVPLGSGEGPSASDMSPQQEDPLSCIRACCMCRPQAEAQKLSFLASICTICEAALEDSGAHYRLCVCPLEVAQCIEELLQEEPAERLDTELWQQAMNAIAAMSRAWLLPEERKSSLLRACLGSVLRLPRHEDTQDRDAALYMETMEALHRLLQVLVGSAGTSVLMELQNILELLLPFTTCQLAAVEERAMACIARLLAFSNTCPLPEVCSCFTGAVVLRHQCTENQRFPVLGKLAGQLILCCTSTDEGTRDEAMKAVRQLFIFIASQRMWMWQKDPKKPQLRERWQTLFYEQVSQENNARKIFRMFLKYLQYPERVSIFLTAIESMTVPSLHSTELAAHMVDVLSAEVHFPPGQVQKIVKVIYSSLPSITAQPALESLGRALLVLASKYPREMVSSLLGCSPTCTSVTITMWKEMLSESLAVEKVLQELLRVLTNHSLYHMSTSTGDRPRVLALAAARILPEIIQLPLVLKEAEAIFPQLFLALLLQVSFTMELTLQEVEIFWEVHQQHHLTPIRAAVQSLKVLLCGVGLQKQMEAIEEQGGWDALLSTVTHLQGVQVVARVMRELPGALRDPIFHQLVELLSTKFCSWEMVAMVFLVEMLECVDLSEELHRVVSLFSTYLQSQSVGMQQLVLRGILQLSKRQDTARKMLGLLPCITEQLQDADSGARAMALPVLSSLLRLLERGKLSLVALELASNLPALFEDESGTVRQLSIHLFLDTLSFVEGREKRKMRKEVYRSLVPLYLHLHDEEESVAKASQKAFLGAARFLHWRRLEHLAEVAQFWQIGECMVCTFPHPRSGSGPLCADPVPFSLQLVERRKSAAQDYLGQSLLYLQSPQEPLRREAVRFIGEP", "length": 887, "header": "tr|A0A8V1ABV0-1|A0A8V1ABV0_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1ABV0-1" }, "locus": { "chromosome": "12", "start_pos": 3102129, "end_pos": 3096914, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066436.1", "url": "https://www.ensembl.org/id/ENSGALT00010066436.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040702.1", "url": "https://www.ensembl.org/id/ENSGALP00010040702.1" } ] } }, { "isoform_ac": "A0A8V1AEJ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABV0/entry#A0A8V1AEJ2-1", "sequence": { "sequence": "MEQRSPSCHQKAWPEKPMISQASRPQWGTDEVCEMQVPLGSGEGPSASDMSPQQEDPLSCIRACCMCRPQAEAQKLSFLASICTICEAALEDSGAHYRLCVCPLEVAQCIEELLQEEPAERLDTELWQQAMNAIAAMSRAWLLPEERKSSLLRACLGSVLRLPRHEDTQDRDAALYMETMEALHRLLQVLVGSAGTSVLMELQNILELLLPFTTCQLAAVEERAMACIARLLAFSNTCPLPEVCSCFTGAVVLRHQCTENQRFPVLGKLAGQLILCCTSTDEGTRDEAMKAVRQLFIFIASQRMWMWQKDPKKPQLRERWQTLFYEQVSQENNARKIFRMFLKYLQYPERVSIFLTAIESMTVPSLHSTELAAHMVDVLSAEVHFPPGQVQKIVKVIYSSLPSITAQPALESLGRALLVLASKYPREMVSSLLGCSPTCTSVTITMWKEMLSESLAVEKVLQELLRVLTNHSLYHMSTSTGDRPRVLALAAARILPEIIQLPLVLKEAEAIFPQLFLALLLQVSFTMELTLQEVEIFWEVHQQHHLTPIRAAVQSLKVLLCGVGLQKQMEAIEEQGGWDALLSTVTHLQGVQVVARVMRELPGALRDPIFHQLVELLSTKFCSWEMVAMVFLVEMLECVDLSEELHRVVSLFSTYLQSQSVGMQQLVLRGILQLSKRQDTARKMLGLLPCITEQLQDADSGARAMALPVLSSLLRLLERGKLSLVALELASNLPALFEDESGTVRQLSIHLFLDTLSFVEGREKRKMRKEVYRSLVPLYLHLHDEEESVAKASQKAFLGAARFLHWRRLEHLAEVAQFWQIGECMLVERRKSAAQDYLGQSLLYLQSPQEPLRREAVRFIELIGRHEIPTVRSRWWRFGRR", "length": 881, "header": "tr|A0A8V1AEJ2-1|A0A8V1AEJ2_CHICK Computationally mapped isoform of Maestro heat-like repeat-containing protein family member 7 OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1ABV0-1" }, "locus": { "chromosome": "12", "start_pos": 3102129, "end_pos": 3096773, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066435.1", "url": "https://www.ensembl.org/id/ENSGALT00010066435.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040701.1", "url": "https://www.ensembl.org/id/ENSGALP00010040701.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABV0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABV0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 470, "end_pos": 472, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1ABV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABV0" }, { "id": "PF23210", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23210" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "MROH2B-like HEAT-repeats", "eco_id": "ECO_0000259", "start_pos": 70, "end_pos": 191, "start_aa": "Gln", "end_aa": "Val", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1ABV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABV0" }, { "id": "PF21047", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21047" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Maestro-like HEAT-repeats", "eco_id": "ECO_0000259", "start_pos": 243, "end_pos": 461, "start_aa": "Val", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1ABV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABV0" }, { "id": "PF23227", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23227" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Maestro/Maestro-like HEAT-repeats", "eco_id": "ECO_0000259", "start_pos": 652, "end_pos": 885, "start_aa": "Phe", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 470, "end_pos": 472 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1ABV6-1", "uniprot_ac": "A0A8V1ABV6", "uniprot_id": "A0A8V1ABV6_CHICK", "mass": { "chemical_mass": 176917.0, "monoisotopic_mass": 176917.0 }, "refseq": {}, "gene_names": [ { "name": "COL27A1", "type": "recommended", "evidence": [ { "id": "A0A8V1ABV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABV6" } ] } ], "protein_names": [ { "name": "Collagen type XXVII alpha 1 chain", "type": "synonym", "evidence": [ { "id": "A0A8V1ABV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABV6/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABV6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABV6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "COL27A1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABV6", "locus": {} } ], "crossref": [ { "id": "IPR000885", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000885", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008160", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008160", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048287", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048287", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050938", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050938", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ABV6", "url": "https://www.orthodb.org/?gene=A0A8V1ABV6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR37456", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR37456", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR37456:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR37456:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01391", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01391", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01410", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01410", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-1650814", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1650814", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-2022090", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2022090", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-8948216", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8948216", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1ABV6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABV6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ABV6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABV6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEPESEPVSRFRATAAGRGGFCFVWTVLCFSWFLGFTQGNSEDVDVLQRLGLGGRRPSSGLSSSHAIPQGVIPLKSGVIFTQRARVEAPISTIFPTGSSTDLLLVLSLCSHRNNNAFLFAVKSKKKKLQLGVQFVPGKIIVYVGHKRSVYFDYNVHDGQWHNMAINIRGQTVTLFTSCGKHRVHADLHFKKDEALDPHGSFLFGKMNHHSVQFEGAICQFDIYPSAKAAHHYCKYLKKQCRQADTYRPNLPPLIPILPRDPSASPSTPQHMEPLLQGLKNLTTASPSLALGRVTAPLKTRGSGATTVALVSSQPPLPRQTTKATKVTVAPSPAPSSAGTQPPTRSLPRGTVTTLRVSRPTSSTHTEKTPLPGAKKALPASPSPATASRKETKQETKKKINQIPTTKSSEAPSTVKPTRRRADNATSSIHFVTLKQTPQTPTTGPLPKKHLPTPTRKGDPGNVPLVYTKPPLGAARPVSRAQAFNLTTPAATDGYQIFDPLGPTPFPFLLGYPGVKGDRGPQGPPGLPGLPGPPGKRGSRGPPGPHGNPGSPGPPGLKGQKGDPGLSPGKARRGPKGDVGLPGLTGFPGPPGRKGYKGYPGPPGHPGDQGERGPAGSPGAKGYPGRQGLPGPIGEAGPKGSRGYIGLPGLFGLPGADGERGIPGVPGKRGKMGRPGFPGDFGERGPPGIDGNPGELGAPGPPGVLGLIGDMGSVGPIGYPGPKGLKGLIGNPGEHGLKGDKGDQGGAGLPGDIGFQGDKGSHGLPGVPGARGKPGPVGKVGDIGPMGFPGPPGPEGFPGDIGPPGENGPEGPKGKPGARGLPGPRGLPGQEGDEGPLGPPGVPGSEGRPGRKGFPGRPGPDGPKGEPGNHGRPGKVGEQGLMGFIGPVGEPGIVGEKGDRGSVGPPGPPGVKGSMGHPGIPGAVGFPGIPGPAGPAGARGAPGIRGVKGRRGARGPDGPVGEPGSRGAKGRPGEPGKLGPDGLQGKMGETGETGSRGFPGIQGPSGPPGAKGAPGDPGPQGPQGPPGPLGEIGHKGPPGPMGQPGLAGEPGMKGDPGQLGVPGEQGLIGQRGEMGLEGDSGPPGPDGAKGDKGEQGLDGEKGEKGTEGLKGKEGPPGYPGITGVRGPEGKPGKQGEKGRPGQKGSKGYQGQLGETGPPGKEGPKGNQGPKGSRGTLGPMGAPGRMGAQGEPGLKGYQGHAGPPGPIGPPGPKGEKGEQGDDGKVEGPQGPPGDRGPVGDRGDRGEPGDPGYPGQEGLDGERGKPGQQGLPGDPGPPGQPGAKGSKGDVGQKGKQGARGSAGSRGSPGTLGLPGPRGVVGRQGQEGAPGVDGVPGKDGVPGVLGEQGDDGEEGVTGMTGKRGNPGVPGLPGAQGPPGFKGERGLPGQTGQTGKRGSLGGMGLPGSPGDPGPKGQPGDFGEAGFPGIAGIFGPKGPPGDPGFKGIQGPRGPPGIMGKEGIIGPLGILGPTGSPGPKGDKGSRGDVGLRGPRGPPGPRGQPGPPGPPGFPASFQQDGFGAAFRTLVDSNVALKTEGYQHPDLLMLDHGGEIFKTLHYLSNLIQSIKRPLGTKENPARICRDLMNCEQKMKDGTYWIDPNLGCSSDTIQVICNFTNGGQTCLSPITVSKLDFDIGRVQMNFLRLLSSEVVQHITIHCLNTSVWREGSAEKPSQKAVRFKAWNGQMFEAEGQLRPEVAADDCKIKDGRWHRTLFSFRTQDTQQLPIINIYNLPPSEPGKHYHLEVGPVCFL", "length": 1745, "header": "tr|A0A8V1ABV6-1|A0A8V1ABV6_CHICK Isoform 1 of Collagen type XXVII alpha 1 chain OS=Gallus gallus OX=9031 GN=COL27A1 PE=4 SV=1 CANONICAL=A0A8V1ABV6-1" }, "isoforms": [ { "isoform_ac": "A0A8V1ABV6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABV6/entry#A0A8V1ABV6-1", "sequence": { "sequence": "MEPESEPVSRFRATAAGRGGFCFVWTVLCFSWFLGFTQGNSEDVDVLQRLGLGGRRPSSGLSSSHAIPQGVIPLKSGVIFTQRARVEAPISTIFPTGSSTDLLLVLSLCSHRNNNAFLFAVKSKKKKLQLGVQFVPGKIIVYVGHKRSVYFDYNVHDGQWHNMAINIRGQTVTLFTSCGKHRVHADLHFKKDEALDPHGSFLFGKMNHHSVQFEGAICQFDIYPSAKAAHHYCKYLKKQCRQADTYRPNLPPLIPILPRDPSASPSTPQHMEPLLQGLKNLTTASPSLALGRVTAPLKTRGSGATTVALVSSQPPLPRQTTKATKVTVAPSPAPSSAGTQPPTRSLPRGTVTTLRVSRPTSSTHTEKTPLPGAKKALPASPSPATASRKETKQETKKKINQIPTTKSSEAPSTVKPTRRRADNATSSIHFVTLKQTPQTPTTGPLPKKHLPTPTRKGDPGNVPLVYTKPPLGAARPVSRAQAFNLTTPAATDGYQIFDPLGPTPFPFLLGYPGVKGDRGPQGPPGLPGLPGPPGKRGSRGPPGPHGNPGSPGPPGLKGQKGDPGLSPGKARRGPKGDVGLPGLTGFPGPPGRKGYKGYPGPPGHPGDQGERGPAGSPGAKGYPGRQGLPGPIGEAGPKGSRGYIGLPGLFGLPGADGERGIPGVPGKRGKMGRPGFPGDFGERGPPGIDGNPGELGAPGPPGVLGLIGDMGSVGPIGYPGPKGLKGLIGNPGEHGLKGDKGDQGGAGLPGDIGFQGDKGSHGLPGVPGARGKPGPVGKVGDIGPMGFPGPPGPEGFPGDIGPPGENGPEGPKGKPGARGLPGPRGLPGQEGDEGPLGPPGVPGSEGRPGRKGFPGRPGPDGPKGEPGNHGRPGKVGEQGLMGFIGPVGEPGIVGEKGDRGSVGPPGPPGVKGSMGHPGIPGAVGFPGIPGPAGPAGARGAPGIRGVKGRRGARGPDGPVGEPGSRGAKGRPGEPGKLGPDGLQGKMGETGETGSRGFPGIQGPSGPPGAKGAPGDPGPQGPQGPPGPLGEIGHKGPPGPMGQPGLAGEPGMKGDPGQLGVPGEQGLIGQRGEMGLEGDSGPPGPDGAKGDKGEQGLDGEKGEKGTEGLKGKEGPPGYPGITGVRGPEGKPGKQGEKGRPGQKGSKGYQGQLGETGPPGKEGPKGNQGPKGSRGTLGPMGAPGRMGAQGEPGLKGYQGHAGPPGPIGPPGPKGEKGEQGDDGKVEGPQGPPGDRGPVGDRGDRGEPGDPGYPGQEGLDGERGKPGQQGLPGDPGPPGQPGAKGSKGDVGQKGKQGARGSAGSRGSPGTLGLPGPRGVVGRQGQEGAPGVDGVPGKDGVPGVLGEQGDDGEEGVTGMTGKRGNPGVPGLPGAQGPPGFKGERGLPGQTGQTGKRGSLGGMGLPGSPGDPGPKGQPGDFGEAGFPGIAGIFGPKGPPGDPGFKGIQGPRGPPGIMGKEGIIGPLGILGPTGSPGPKGDKGSRGDVGLRGPRGPPGPRGQPGPPGPPGFPASFQQDGFGAAFRTLVDSNVALKTEGYQHPDLLMLDHGGEIFKTLHYLSNLIQSIKRPLGTKENPARICRDLMNCEQKMKDGTYWIDPNLGCSSDTIQVICNFTNGGQTCLSPITVSKLDFDIGRVQMNFLRLLSSEVVQHITIHCLNTSVWREGSAEKPSQKAVRFKAWNGQMFEAEGQLRPEVAADDCKIKDGRWHRTLFSFRTQDTQQLPIINIYNLPPSEPGKHYHLEVGPVCFL", 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This record is derived from a genomic sequence (NC_052536.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. 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OS=Gallus gallus OX=9031 GN=NAIF1 PE=4 SV=1 CANONICAL=A0A8V1ABX9-1" }, "isoforms": [ { "isoform_ac": "A0A8V1ABX9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABX9/entry#A0A8V1ABX9-1", "sequence": { "sequence": "MTVQRSSRGARISADRQAGGPIRAMASPPAPPAKKRKMNFSEREVEIIVEELERGKHLLINHFNAGVPLAAKAAAWHDILRRVNAVATCHRELPEVKKKWSDLKTEVRRKVAQVRAAMEGGGESQNGGGAGTEGEDPTGATAAPVILTPMQQRICNLLGEATIISLPSGDCGAADGTEIPITASATTVTLTQIPAETTYHSLEDGVVEYCTTEAPTTVTAEAPLEMMAHQHEVSAKPQELKSRIALNSAKLLQEQRVTNLHVKEIAQHLEQQNDLLQMIRRSQEVQACAQERQAQAMEGTQAALSALIQVLRPMIKDFRRFLQSNTPSPSVTADPNQTGQQDGIIQ", "length": 346, "header": "tr|A0A8V1ABX9-1|A0A8V1ABX9_CHICK Isoform 1 of Nuclear apoptosis inducing factor 1 OS=Gallus gallus OX=9031 GN=NAIF1 PE=4 SV=1 CANONICAL=A0A8V1ABX9-1" }, "locus": { "chromosome": "17", "start_pos": 5497963, "end_pos": 5495972, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067995.1", "url": "https://www.ensembl.org/id/ENSGALT00010067995.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041738.1", "url": "https://www.ensembl.org/id/ENSGALP00010041738.1" } ] } }, { "isoform_ac": "A0A8V1AET7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABX9/entry#A0A8V1AET7-1", "sequence": { "sequence": "MHPVASRGGAMASPPAPPAKKRKMNFSEREVEIIVEELERGKHLLINHFNAGVPLAAKAAAWHDILRRVNAVATCHRELPEVKKKWSDLKTEVRRKVAQVRAAMEGGGESQNGGGAGTEGEDPTGATAAPVILTPMQQRICNLLGEATIISLPSGDCGAADGTEIPITASATTVTLTQIPAETTYHSLEDGVVEYCTTEAPTTVTAEAPLEMMAHQHEVSAKPQELKSRIALNSAKLLQEQRVTNLHVKEIAQHLEQQNDLLQMIRRSQEVQACAQERQAQAMEGTQAALSALIQVLRPMIKDFRRFLQSNTPSPSVTADPNQTGQQDGIIQ", "length": 332, "header": "tr|A0A8V1AET7-1|A0A8V1AET7_CHICK Computationally mapped isoform of Nuclear apoptosis inducing factor 1 OS=Gallus gallus OX=9031 GN=NAIF1 PE=4 SV=1 CANONICAL=A0A8V1ABX9-1" }, "locus": { "chromosome": "17", "start_pos": 5497963, "end_pos": 5495780, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067997.1", "url": "https://www.ensembl.org/id/ENSGALT00010067997.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041740.1", "url": "https://www.ensembl.org/id/ENSGALP00010041740.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 138, "start_aa": "Thr", "end_pos": 138, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr138", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABX9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABX9" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABX9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABX9" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABX9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABX9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "negative regulation of cell growth", "id": "GO:0030308", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030308", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABX9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABX9" } ], "pmid": "" }, { "name": "regulation of mitochondrial membrane permeability involved in apoptotic process", "id": "GO:1902108", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902108", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABX9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABX9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 336, "end_pos": 338, "annotation": "n_glycosylation_sequon" }, { "start_pos": 39, "end_pos": 41, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1ABX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABX9" }, { "id": "PF13873", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13873" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Myb/SANT-like DNA-binding", "eco_id": "ECO_0000259", "start_pos": 36, "end_pos": 113, "start_aa": "Arg", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 138 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 336, "end_pos": 338 }, { "start_pos": 39, "end_pos": 41 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1ABY0-1", "uniprot_ac": "A0A8V1ABY0", "uniprot_id": "A0A8V1ABY0_CHICK", "mass": { "chemical_mass": 60368.0, "monoisotopic_mass": 60368.0 }, "refseq": { "ac": "XP_015155406", "name": "polypyrimidine tract-binding protein 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015155406" }, "gene_names": [ { "name": "PTBP1", "type": "recommended", "evidence": [ { "id": "A0A8V1ABY0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABY0" } ] }, { "name": "PTBP1", "type": "synonym", "evidence": [ { "id": "XP_015155406", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015155406" } ] } ], "protein_names": [ { "name": "Polypyrimidine tract-binding protein 1", "type": "recommended", "evidence": [ { "id": "A0A8V1ABY0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABY0/entry#names_and_taxonomy" } ] }, { "name": "polypyrimidine tract-binding protein 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015155406", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015155406" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052559.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015155406", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015155406" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABY0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABY0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PTBP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABY0", "locus": { "chromosome": "28", "start_pos": 3256542, "end_pos": 3228018, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027419", "url": "https://www.ensembl.org/id/ENSGALG00010027419" } ] } } ], "crossref": [ { "id": "A0A8V1ABY0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1ABY0", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd12695", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12695", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12701", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12701", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12777", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12777", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12782", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12782", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "420098", "url": "https://www.ncbi.nlm.nih.gov/gene/420098", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006536", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006536", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021790", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021790", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035000", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035000", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035001", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035001", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055204", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055204", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "NMIYPVT", "url": "https://omabrowser.org/oma/group/NMIYPVT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ABY0", "url": "https://www.orthodb.org/?gene=A0A8V1ABY0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15592", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15592", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF11835", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11835", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13893", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13893", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22976", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22976", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-72163", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72163", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9770562", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9770562", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015155406", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015155406", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1ABY0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABY0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ABY0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABY0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDGIVQDITVGTKRGSDELFSTCVTNGPFIMSSNASSAANGNDSKKFKGDSRSAGVPSRVIHVRKLPSDVTEAEVISLGLPFGKVTNLLMLKGKNQAFIEMNTEEAANTMVNYYTTVTPVLRSQPIYIQFSNHKELKTDNSPNQARAQAALQAVNSVQSGNLALPAPAAAVDAGMAMAGQSPVLRIIVENLFYPVTLDVLHQIFSKFGTVLKIITFTKNNQFQALLQYADPMSAQHAKLSLDGQNIYNACCTLRIDFSKLTSLNVKYNNDKSRDYTRPDLPSGDNQPPLDQTMAAAFGAPGIIPASPYAGAGFPPTFAIPQAAGTVLRLTVQNVHGALAPLAIPAAAAAAAAGRIAIPGLAGAGNSVLLVSNLNPERVTPQCLFILFGVYGDVQRVKILFNKKENALVQMADGNQAQLAMSHLNGQKLHGKPIRITLSKHQTVQLPREGQEDQGLTKDYGNSPLHRFKKPGSKNFQNIFPPSATLHLSNIPPSIAEEDLKMLFSSNGGMVKGFKFFQKDRKMALIQMGSVEEAIQSLIDLHNHDLGENHHLRVSFSKSTI", "length": 560, "header": "tr|A0A8V1ABY0-1|A0A8V1ABY0_CHICK Isoform 1 of Polypyrimidine tract-binding protein 1 OS=Gallus gallus OX=9031 GN=PTBP1 PE=1 SV=1 CANONICAL=A0A8V1ABY0-1" }, "isoforms": [ { "isoform_ac": "A0A8V1ABY0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABY0/entry#A0A8V1ABY0-1", "sequence": { "sequence": "MDGIVQDITVGTKRGSDELFSTCVTNGPFIMSSNASSAANGNDSKKFKGDSRSAGVPSRVIHVRKLPSDVTEAEVISLGLPFGKVTNLLMLKGKNQAFIEMNTEEAANTMVNYYTTVTPVLRSQPIYIQFSNHKELKTDNSPNQARAQAALQAVNSVQSGNLALPAPAAAVDAGMAMAGQSPVLRIIVENLFYPVTLDVLHQIFSKFGTVLKIITFTKNNQFQALLQYADPMSAQHAKLSLDGQNIYNACCTLRIDFSKLTSLNVKYNNDKSRDYTRPDLPSGDNQPPLDQTMAAAFGAPGIIPASPYAGAGFPPTFAIPQAAGTVLRLTVQNVHGALAPLAIPAAAAAAAAGRIAIPGLAGAGNSVLLVSNLNPERVTPQCLFILFGVYGDVQRVKILFNKKENALVQMADGNQAQLAMSHLNGQKLHGKPIRITLSKHQTVQLPREGQEDQGLTKDYGNSPLHRFKKPGSKNFQNIFPPSATLHLSNIPPSIAEEDLKMLFSSNGGMVKGFKFFQKDRKMALIQMGSVEEAIQSLIDLHNHDLGENHHLRVSFSKSTI", "length": 560, "header": "tr|A0A8V1ABY0-1|A0A8V1ABY0_CHICK Isoform 1 of Polypyrimidine tract-binding protein 1 OS=Gallus gallus OX=9031 GN=PTBP1 PE=1 SV=1 CANONICAL=A0A8V1ABY0-1" }, "locus": { "chromosome": "28", "start_pos": 3253687, "end_pos": 3228100, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066482.1", "url": "https://www.ensembl.org/id/ENSGALT00010066482.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040733.1", "url": "https://www.ensembl.org/id/ENSGALP00010040733.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-72163", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72163", "resource": "Reactome", "description": "mRNA Splicing - Major Pathway" }, { "id": "R-GGA-9770562", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9770562", "resource": "Reactome", "description": "mRNA Polyadenylation" } ], "orthologs": [ { "uniprot_canonical_ac": "P17225-1", "protein_name": "Polypyrimidine tract-binding protein 1", "gene_name": "Ptbp1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDGIVPDIAVGTKRGSDELFSTCVSNGPFIMSSSASAANGNDSKKFKGDNRSAGVPSRVIHVRKLPSDVTEGEVISLGLPFGKVTNLLMLKGKNQAFIEMNTEEAANTMVNYYTSVAPVLRGQPIYIQFSNHKELKTDSSPNQARAQAALQAVNSVQSGNLALAASAAAVDAGMAMAGQSPVLRIIVENLFYPVTLDVLHQIFSKFGTVLKIITFTKNNQFQALLQYADPVSAQHAKLSLDGQNIYNACCTLRIDFSKLTSLNVKYNNDKSRDYTRPDLPSGDSQPSLDQTMAAAFGAPGIMSASPYAGAGFPPTFAIPQAAGLSVPNVHGALAPLAIPSAAAAAAASRIAIPGLAGAGNSVLLVSNLNPERVTPQSLFILFGVYGDVQRVKILFNKKENALVQMADGSQAQLAMSHLNGHKLHGKSVRITLSKHQSVQLPREGQEDQGLTKDYGSSPLHRFKKPGSKNFQNIFPPSATLHLSNIPPSVSEDDLKSLFSSNGGVVKGFKFFQKDRKMALIQMGSVEEAVQALIELHNHDLGENHHLRVSFSKSTI", "length": 555 }, "evidence": [ { "id": "A0A8V1ABY0", "url": "https://omabrowser.org/oma/group/A0A8V1ABY0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P26599-3", "protein_name": "Polypyrimidine tract-binding protein 1", "gene_name": "PTBP1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDGIVPDIAVGTKRGSDELFSTCVTNGPFIMSSNSASAANGNDSKKFKGDSRSAGVPSRVIHIRKLPIDVTEGEVISLGLPFGKVTNLLMLKGKNQAFIEMNTEEAANTMVNYYTSVTPVLRGQPIYIQFSNHKELKTDSSPNQARAQAALQAVNSVQSGNLALAASAAAVDAGMAMAGQSPVLRIIVENLFYPVTLDVLHQIFSKFGTVLKIITFTKNNQFQALLQYADPVSAQHAKLSLDGQNIYNACCTLRIDFSKLTSLNVKYNNDKSRDYTRPDLPSGDSQPSLDQTMAAAFGAPGIISASPYAGAGFPPTFAIPQAAGLSVPNVHGALAPLAIPSAAAAAAAAGRIAIPGLAGAGNSVLLVSNLNPERVTPQSLFILFGVYGDVQRVKILFNKKENALVQMADGNQAQLAMSHLNGHKLHGKPIRITLSKHQNVQLPREGQEDQGLTKDYGNSPLHRFKKPGSKNFQNIFPPSATLHLSNIPPSVSEEDLKVLFSSNGGVVKGFKFFQKDRKMALIQMGSVEEAVQALIDLHNHDLGENHHLRVSFSKSTI", "length": 557 }, "evidence": [ { "id": "A0A8V1ABY0", "url": "https://omabrowser.org/oma/group/A0A8V1ABY0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6ICX4-1", "protein_name": "Polypyrimidine tract-binding protein homolog 3", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAESSKVVHVRNVGHEISENDLLQLFQPFGVITKLVMLRAKNQALLQMQDVSSAVSALQFFTNVQPTIRGRNVYVQFSSHQELTTIEQNIHGREDEPNRILLVTIHHMLYPITVDVLHQVFSPYGFVEKLVTFQKSAGFQALIQYQVQQCAASARTALQGRNIYDGCCQLDIQFSNLEELQVNYNNDRSRDYTNPNLPAEQKGRSSHPCYGDTGVAYPQMANTSAIAAAFGGGLPPGITGTNDRCTVLVSNLNADSIDEDKLFNLFSLYGNIVRIKLLRNKPDHALVQMGDGFQAELAVHFLKGAMLFGKRLEVNFSKHPNITPGTDSHDYVNSNLNRFNRNAAKNYRYCCSPTKMIHLSTLPQDVTEEEVMNHVQEHGAVVNTKVFEMNGKKQALVQFENEEEAAEALVCKHATSLGGSIIRISFSQLQTI", "length": 432 }, "evidence": [ { "id": "A0A8V1ABY0", "url": "https://omabrowser.org/oma/group/A0A8V1ABY0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q8WN55-1", "protein_name": "Polypyrimidine tract-binding protein 1", "gene_name": "PTBP1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MDGIVPDIAVGTKRGSDELFSACVTNGPFIMSGTSASTANGNDSKKFKGDSRSAGVPSRVIHIRKLPGDVTEGEVISLGLPFGKVTNLLMLKGKNQAFIEMHTEEAANTMVNYYTSVTPVLRGQPIYIQFSNHKELKTDSSPNQARAQAALQAVNSVQSGNLALAASAAAVDAGMAMAGQSPVLRIIVENLFYPVTLDVLHQIFSKFGTVLKIITFTKNNQFQALLQYADPVSAQHAKLSLDGQNIYNACCTLRIDFSKLTSLNVKYNNDKSRDYTRPDLPSGDSQPSLDQTMAAAFGAPGIMSASPYAGAGFPPTFAIPQAAGLSVPNVHGALAPLAIPSAAAAAAAAGRIAIPGLAGAGNSVLLVSNLNPERVTPQSLFILFGVYGDVQRVKVLFNKKENALVQMADGSQAQLAMSHLNGHKLHGKPVRITLSKHQSVQLPREGQEDQGLTKDYGNSPLHRFKKPGSKNFQNIFPPSATLHLSNIPPSISEDDLKILFSSNGGIVKGFKFFQKDRKMALIQMGSVEEAIQALIDLHNHDLGENHHLRVSFSKSTI", "length": 557 }, "evidence": [ { "id": "A0A8V1ABY0", "url": "https://omabrowser.org/oma/group/A0A8V1ABY0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "pre-mRNA binding", "id": "GO:0036002", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036002", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABY0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABY0" } ], "pmid": "" }, { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABY0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABY0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 10, "go_terms": [ { "name": "IRES-dependent viral translational initiation", "id": "GO:0075522", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0075522", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABY0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABY0" } ], "pmid": "" }, { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABY0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABY0" } ], "pmid": "" }, { "name": "negative regulation of neuron differentiation", "id": "GO:0045665", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045665", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABY0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABY0" } ], "pmid": "" }, { "name": "RNA splicing", "id": "GO:0008380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008380", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABY0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABY0" } ], "pmid": "" }, { "name": "negative regulation of mRNA splicing, via spliceosome", "id": "GO:0048025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048025", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABY0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABY0" } ], "pmid": "" }, { "name": "regulation of cell differentiation", "id": "GO:0045595", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045595", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABY0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABY0" } ], "pmid": "" }, { "name": "positive regulation of calcineurin-NFAT signaling cascade", "id": "GO:0070886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABY0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABY0" } ], "pmid": "" }, { "name": "regulation of RNA splicing", "id": "GO:0043484", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043484", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABY0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABY0" } ], "pmid": "" }, { "name": "negative regulation of muscle cell differentiation", "id": "GO:0051148", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051148", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABY0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABY0" } ], "pmid": "" }, { "name": "regulation of alternative mRNA splicing, via spliceosome", "id": "GO:0000381", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000381", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABY0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABY0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABY0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABY0" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABY0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABY0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 34, "end_pos": 36, "annotation": "n_glycosylation_sequon" }, { "start_pos": 42, "end_pos": 44, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { 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"o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1ABY7-1", "uniprot_ac": "A0A8V1ABY7", "uniprot_id": "A0A8V1ABY7_CHICK", "mass": { "chemical_mass": 23305.0, "monoisotopic_mass": 23305.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "RNase H type-1 domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8V1ABY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABY7/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABY7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABY7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABY7", "locus": {} } ], "crossref": [ { "id": "A0A8V1ABY7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1ABY7", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR002156", "url": 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The reference sequence was derived from JAENSK010000252.1. On Oct 20, 2021 this sequence version replaced XP_015148563.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.", "evidence": [ { "database": "RefSeq", "id": "NP_001383522", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001383522" } ] }, { "annotation": "At later stages, Gata2 expression became prominent in vestibular and cochlear nonsensory epithelia", "evidence": [ { "database": "RefSeq", "id": "NP_001383522", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001383522" }, { "database": "PubMed", "id": "17103399", "url": "https://glygen.org/publication/PubMed/17103399" } ] }, { "annotation": "Data establish Gata2 and Gata3 as essential members of the transcription factor network controlling sympathetic neuron development", "evidence": [ { "database": "RefSeq", "id": "NP_001383522", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001383522" }, { "database": "PubMed", "id": "15329349", "url": "https://glygen.org/publication/PubMed/15329349" } ] }, { "annotation": "Gata2 influences the site of primitive streak formation and its role is independent from, and upstream of, Vg1 and Wnt", "evidence": [ { "database": "RefSeq", "id": "NP_001383522", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001383522" }, { "database": "PubMed", "id": "23093427", "url": "https://glygen.org/publication/PubMed/23093427" } ] }, { "annotation": "Results provide new insights into the selective roles of Gata2 within the genetic model of V2 interneurons development and in particular on the hierarchy between V2-transcription factors", "evidence": [ { "database": "RefSeq", "id": "NP_001383522", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001383522" }, { "database": "PubMed", "id": "25369423", "url": "https://glygen.org/publication/PubMed/25369423" } ] }, { "annotation": "Within the rostral hindbrain, the Shh-activated homeodomain proteins Nkx2.2 and Nkx6.1 cooperate to induce the closely related zinc-finger transcription factors Gata2 and Gata3. (Gata2)", "evidence": [ { "database": "RefSeq", "id": "NP_001383522", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001383522" }, { "database": "PubMed", "id": "14973276", "url": "https://glygen.org/publication/PubMed/14973276" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AC24", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC24" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "GATA2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC24", "locus": { "chromosome": "12", "start_pos": 9395368, "end_pos": 9385018, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010026920", "url": "https://www.ensembl.org/id/ENSGALG00010026920" } ] } } ], "crossref": [ { "id": "A0A8V1AC24", "url": 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"header": "tr|A0A8V1AC24-1|A0A8V1AC24_CHICK Isoform 1 of GATA binding protein 2 OS=Gallus gallus OX=9031 GN=GATA2 PE=4 SV=1 CANONICAL=A0A8V1AC24-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AC24-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC24/entry#A0A8V1AC24-1", "sequence": { "sequence": "MEVATDQPRWMTHHAVLNGQHPESHHPGLAHNYMEPAQLLPPDEVDVFFNHLDSQGNPYYANSAHARARVSYSQAHARLTGSQMCRPHLIHSPGIPWLDSSKAALSAHHHNPWTVNPFTKTPLHPSAAGAPGAISVYPGSSTSSTASVSSLTPASHSGSHLFGFPPTPPKEVSPDPNSTSAASPSSSAGARQEDKDSIKYQVSLSEGMKMESASPLRSSLTSMGAQPSTHHPIPTYPSYVPAAHDYSSSLFHPGSFLGGPASSFTPKPRSKARSCSERNPVSSCFHLEGRECVNCGATATPLWRRDGTGHYLCNACGLYHKMNGQNRPLIKPKRRLSAARRAGTCCANCQTTTTTLWRRNANGDPVCNACGLYYKLHNVNRPLTMKKEGIQTRNRKMSNKSKKSKKGSECFEELSKCMQEKSSPFSAAALASHMAPMGHLPPFSHSGHILPTPTPIHPSSSISFGHPHPSSMVTAMG", "length": 477, "header": "tr|A0A8V1AC24-1|A0A8V1AC24_CHICK Isoform 1 of GATA binding protein 2 OS=Gallus gallus OX=9031 GN=GATA2 PE=4 SV=1 CANONICAL=A0A8V1AC24-1" }, "locus": { "chromosome": "12", "start_pos": 9393969, 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"publication": [ { "title": "Gata2 specifies serotonergic neurons downstream of sonic hedgehog.", "journal": "Development (Cambridge, England)", "date": "2004-03", "authors": "Craven Sarah E, Lim Kim-Chew, Ye Weilan, Engel James Douglas, de Sauvage Frederic, Rosenthal Arnon", "evidence": [ { "database": "RefSeq", "id": "NP_001383522", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001383522" } ], "reference": [ { "type": "PubMed", "id": "14973276", "url": "https://glygen.org/publication/PubMed/14973276" } ] }, { "title": "Essential role of Gata transcription factors in sympathetic neuron development.", "journal": "Development (Cambridge, England)", "date": "2004-10", "authors": "Tsarovina Konstantina, Pattyn Alexandre, Stubbusch Jutta, M\u00fcller Frank, van der Wees Jacqueline, Schneider Carolin, Brunet Jean-Francois, Rohrer Hermann", "evidence": [ { "database": "RefSeq", "id": "NP_001383522", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001383522" } ], "reference": [ { "type": 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"MWGPRQPGQRWWQRAVRRRLPVLGWLPRYSLSCLRLDLTAGVTVGLTVVPQALAYAEVAGLPVQYGLYSSFVGCFVYCLLGTAKDVTLGPTAIMSLLVSSYAFHDPAYAVLLAFLSGCIQLAMGLLHLGFLLDFVSCPVIKGFTSAASITIGFNQVKNILGLQGIPRQFFLQVYETLRRIGEARAGDAILGLSCLAALAGLRAMKSRLHPTASTEPLAARASVLLVRSCATARNALVVLAAGLVAYSFQLSGSQPLTLTGSVPCGLPPFRPPPFSKAVPNGTVPFGRMVQDMGAGLAVVPLVGVLETVAIAKAFASQNDYRIDANQELLAMGTANILGSFFSSYPITGSFGRGWGAPGLPAAPPAGPAQGLCRQQDGQRMALCFRTAVNAQTGVCTPMGGLVTGTLVLLSLAYLTSLFCYIPKAALAAVIISAVVPMFDARIFRTLWRVKRLDLIPLCVTFLLCFWEVQYGIMAGVLVSGILLLYSVARPPIKVLEQGVLLVQPGSSLHFPAADHLQDIIRDRALAASPPCSVILDCHHVSSIDYTAVVGLAELLQELHKHGISLVFCSLQDPVLRALLAADLEGFRHFPSWEEAARCSEAELGGSRAACIDSTGESSLLPAGLIQ", "length": 626, "header": "tr|A0A8V1AC26-1|A0A8V1AC26_CHICK Isoform 1 of Solute carrier family 26 member 11 OS=Gallus gallus OX=9031 GN=SLC26A11 PE=4 SV=1 CANONICAL=A0A8V1AC26-1" }, "locus": { "chromosome": "18", "start_pos": 10178016, "end_pos": 10172475, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070865.1", "url": "https://www.ensembl.org/id/ENSGALT00010070865.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043556.1", "url": "https://www.ensembl.org/id/ENSGALP00010043556.1" } ] } }, { "isoform_ac": "A0A8V1ALH8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC26/entry#A0A8V1ALH8-1", "sequence": { "sequence": "MWGPRQPGQRWWQRAVRRRLPVLGWLPRYSLSCLRLDLTAGVTVGLTVVPQALAYAEVAGLPVQYGLYSSFVGCFVYCLLGTAKDVTLGPTAIMSLLVSSYAFHDPAYAVLLAFLSGCIQLAMGLLHLGFLLDFVSCPVIKGFTSAASITIGFNQVKNILGLQGIPRQFFLQVYETLRRIGEARAGDAILGLSCLAALAGLRAMKSRLHPTASTEPLAARASVLLVRSCATARNALVVLAAGLVAYSFQLSGSQPLTLTGSVPCGLPPFRPPPFSKAVPNGTVPFGRMVQDMGAGLAVVPLVGVLETVAIAKAFASQNDYRIDANQELLAMGTANILGSFFSSYPITGSFGRTAVNAQTGVCTPMGGLVTGTLVLLSLAYLTSLFCYIPKAALAAVIISAVVPMFDARIFRTLWRVKRLDLIPLCVTFLLCFWEVQYGIMAGVLVSGILLLYSVARPPIKHRHRALSSWIATTSAALTTQRWWGWLSCCRSCTSTASRWCSAACRTRFSEPCWPQTWRDSDIFPAGRRQRDVAKRSWGAAEQPALTAPVRARCCPRGSSSEAERWCGPRSVPQEPLLVAPEAAHPVSARAGCAWGRDVGTEEQPDGSPLPPG", "length": 612, "header": "tr|A0A8V1ALH8-1|A0A8V1AC26_CHICK Computationally mapped isoform of Solute carrier family 26 member 11 OS=Gallus gallus OX=9031 GN=SLC26A11 PE=4 SV=1 CANONICAL=A0A8V1AC26-1" }, "locus": { "chromosome": "18", "start_pos": 10178016, "end_pos": 10172318, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070868.1", "url": "https://www.ensembl.org/id/ENSGALT00010070868.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043559.1", "url": "https://www.ensembl.org/id/ENSGALP00010043559.1" } ] } }, { "isoform_ac": "A0A8V1AN29-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC26/entry#A0A8V1AN29-1", "sequence": { "sequence": "MWGPRQPGQRWWQRAVRRRLPVLGWLPRYSLSCLRLDLTAGVTVGLTVVPQALAYAEVAGLPVQYGLYSSFVGCFVYCLLGTAKDVTLGPTAIMSLLVSSYAFHDPAYAVLLAFLSGCIQLAMGLLHLGFLLDFVSCPVIKGFTSAASITIGFNQVKNILGLQGIPRQFFLQVYETLRRIGEARAGDAILGLSCLAALAGLRAMKSRLHPTASTEPLAARASVLLVRSCATARNALVVLAAGLVAYSFQLSGSQPLTLTGSVPCGLPPFRPPPFSKAVPNGTVPFGRMVQDMGAGLAVVPLVGVLETVAIAKAFASQNDYRIDANQELLAMGTANILGSFFSSYPITGSFGRTAVNAQTGVCTPMGGLVTGTLVLLSLAYLTSLFCYIPKAALAAVIISAVVPMFDARIFRTLWRVKRLDLIPLCVTFLLCFWEVQYGIMAGVLVSGILLLYSVARPPIKVLEQGVLLVQPGSSLHFPAADHLQDIIRDRALAGPGSPSPAGRRLGGIPTFSQLGGGSAM", "length": 520, "header": "tr|A0A8V1AN29-1|A0A8V1AC26_CHICK Computationally mapped isoform of Solute carrier family 26 member 11 OS=Gallus gallus OX=9031 GN=SLC26A11 PE=4 SV=1 CANONICAL=A0A8V1AC26-1" }, "locus": { "chromosome": "18", "start_pos": 10178016, "end_pos": 10172560, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070871.1", "url": "https://www.ensembl.org/id/ENSGALT00010070871.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043562.1", "url": "https://www.ensembl.org/id/ENSGALP00010043562.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-174362", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-174362", "resource": "Reactome", "description": "Transport and metabolism of PAPS" }, { "id": "R-GGA-427601", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-427601", "resource": "Reactome", "description": "Inorganic anion exchange by SLC26 transporters" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AC26", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC26" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AC26", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC26" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AC26", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC26" } ], "pmid": "" }, { "name": "basolateral plasma membrane", "id": "GO:0016323", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016323", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AC26", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC26" } ], "pmid": "" }, { "name": "lysosomal membrane", "id": "GO:0005765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005765", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AC26", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC26" } ], "pmid": "" }, { "name": "apical plasma membrane", "id": "GO:0016324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016324", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AC26", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC26" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AC26", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC26" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "chloride channel activity", "id": "GO:0005254", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005254", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AC26", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC26" } ], "pmid": "" }, { "name": "sulfate transmembrane transporter activity", "id": "GO:0015116", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015116", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AC26", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC26" } ], "pmid": "" }, { "name": "chloride:bicarbonate antiporter activity", "id": "GO:0140900", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140900", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AC26", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC26" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "chloride transmembrane transport", "id": "GO:1902476", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902476", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AC26", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC26" } ], "pmid": "" }, { "name": "sulfate transmembrane transport", "id": "GO:1902358", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902358", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AC26", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC26" } ], "pmid": "" }, { "name": "transmembrane transport", "id": "GO:0055085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055085", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AC26", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC26" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 280, "end_pos": 282, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AC26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC26" }, { "id": "PS50801", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50801" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "STAS", "eco_id": "ECO_0000259", "start_pos": 497, "end_pos": 583, "start_aa": "Gln", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 280, "end_pos": 282 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AC39-1", "uniprot_ac": "A0A8V1AC39", "uniprot_id": "A0A8V1AC39_CHICK", "mass": { "chemical_mass": 95659.0, "monoisotopic_mass": 95659.0 }, "refseq": { "ac": "XP_415671", "name": "centrosomal protein of 95 kDa isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_415671" }, "gene_names": [ { "name": "CEP95", "type": "recommended", "evidence": [ { "id": "A0A8V1AC39", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC39" } ] }, { "name": "CEP95", "type": "synonym", "evidence": [ { "id": "XP_415671", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_415671" } ] } ], "protein_names": [ { "name": "Centrosomal protein 95", "type": "synonym", "evidence": [ { "id": "A0A8V1AC39", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC39/entry#names_and_taxonomy" } ] }, { "name": "centrosomal protein of 95 kDa isoform X1", "type": "synonym", "evidence": [ { "id": "XP_415671", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_415671" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052549.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_415671.3. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_415671", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_415671" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AC39", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC39" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CEP95", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC39", "locus": { "chromosome": "18", "start_pos": 7543350, "end_pos": 7529301, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029306", "url": "https://www.ensembl.org/id/ENSGALG00010029306" } ] } } ], "crossref": [ { "id": "A0A8V1AC39", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AC39", "database": "AlphaFoldDB", "categories": [] }, { "id": "417419", "url": "https://www.ncbi.nlm.nih.gov/gene/417419", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026619", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026619", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036872", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036872", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044039", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044039", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "KHSQPWK", "url": "https://omabrowser.org/oma/group/KHSQPWK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AC39", "url": "https://www.orthodb.org/?gene=A0A8V1AC39", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AJF6", "url": "https://www.orthodb.org/?gene=A0A8V1AJF6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AN32", "url": "https://www.orthodb.org/?gene=A0A8V1AN32", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22545", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22545", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22545:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22545:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF19016", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19016", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_415671", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_415671", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AC39", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC39", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AC39-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC39-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJF6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJF6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJF6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJF6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AN32", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN32", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AN32-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN32-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGSAEGTDWVDVANDLLRSCHVNQHIKHLSECGADVFVRLYESILGERVPDFIATPRSQEDDAHNVQAVIDSLALDYLQVSLSHITGENIVKGERESIRNLLEIFDGLLEYLTEEGSESSSQNGDETHVVPNSKIQVVSPEQLESNAGQLLPPLKLSSVDGSQSECFVPLYDVDGLESTSELIQLGDTAHSFSERGEGSLESIQGAEVPKQHFSSSAQRLREPICQAVPLLPPFQPAEARSCDPVHRDHQSLDSQSAALVNSQELESPTLETQTSEGVSGALLSRKIPAGDKMVSNDAEDNVKVPWVYGTSTSASHLDQKFSLHTEQITQPPSPESRHLPRKKRYENSTIDSLEEPLSHRTTKENLSKQELHQVSQKLSHRLNELDAMLKRALGGRTREEVTDEDNMSQHSDSVMDYRRRRAERDIPHLKYPSRTRSLSPSSPSTQHQRFSESGDILCSNGKGQVKKIHNKLQKEKDERTQEAKRVAKAYENELRIYEAQERLRLSKLREEVKELEQEYKENIFKESPKIPQPVKVYSRKTTPWNPRYSQWIPKRGTVKPKKAAPMKVRDDDLLVQLLEEFPHLHISQHTMNKMWRQQLAQTEQLKAASGRARLKLQNEVQQALKKHELLVAIIKKDRDHNKRLQEFKQRIYRQKWTQNKVREKRQQVARARKYYEDYRVQLRAKMMRARTREERIFKNLFEEGLEIQKQRLKDLRAYAQEMRAEQRREHQNELESMENYYRDQFSMLAEAVSRERQEIQTREKAQTQMLQKTKRELRSRMEKEIQQLQTAIMQNDDETFFQELEADRLRSRLQMASFQYNKSGFS", "length": 826, "header": "tr|A0A8V1AC39-1|A0A8V1AC39_CHICK Isoform 1 of Centrosomal protein 95 OS=Gallus gallus OX=9031 GN=CEP95 PE=4 SV=1 CANONICAL=A0A8V1AC39-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AC39-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC39/entry#A0A8V1AC39-1", "sequence": { "sequence": "MGSAEGTDWVDVANDLLRSCHVNQHIKHLSECGADVFVRLYESILGERVPDFIATPRSQEDDAHNVQAVIDSLALDYLQVSLSHITGENIVKGERESIRNLLEIFDGLLEYLTEEGSESSSQNGDETHVVPNSKIQVVSPEQLESNAGQLLPPLKLSSVDGSQSECFVPLYDVDGLESTSELIQLGDTAHSFSERGEGSLESIQGAEVPKQHFSSSAQRLREPICQAVPLLPPFQPAEARSCDPVHRDHQSLDSQSAALVNSQELESPTLETQTSEGVSGALLSRKIPAGDKMVSNDAEDNVKVPWVYGTSTSASHLDQKFSLHTEQITQPPSPESRHLPRKKRYENSTIDSLEEPLSHRTTKENLSKQELHQVSQKLSHRLNELDAMLKRALGGRTREEVTDEDNMSQHSDSVMDYRRRRAERDIPHLKYPSRTRSLSPSSPSTQHQRFSESGDILCSNGKGQVKKIHNKLQKEKDERTQEAKRVAKAYENELRIYEAQERLRLSKLREEVKELEQEYKENIFKESPKIPQPVKVYSRKTTPWNPRYSQWIPKRGTVKPKKAAPMKVRDDDLLVQLLEEFPHLHISQHTMNKMWRQQLAQTEQLKAASGRARLKLQNEVQQALKKHELLVAIIKKDRDHNKRLQEFKQRIYRQKWTQNKVREKRQQVARARKYYEDYRVQLRAKMMRARTREERIFKNLFEEGLEIQKQRLKDLRAYAQEMRAEQRREHQNELESMENYYRDQFSMLAEAVSRERQEIQTREKAQTQMLQKTKRELRSRMEKEIQQLQTAIMQNDDETFFQELEADRLRSRLQMASFQYNKSGFS", "length": 826, "header": "tr|A0A8V1AC39-1|A0A8V1AC39_CHICK Isoform 1 of Centrosomal protein 95 OS=Gallus gallus OX=9031 GN=CEP95 PE=4 SV=1 CANONICAL=A0A8V1AC39-1" }, "locus": { "chromosome": "18", "start_pos": 7542092, "end_pos": 7529563, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070875.1", "url": "https://www.ensembl.org/id/ENSGALT00010070875.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043566.1", "url": "https://www.ensembl.org/id/ENSGALP00010043566.1" } ] } }, { "isoform_ac": "A0A8V1AJF6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC39/entry#A0A8V1AJF6-1", "sequence": { "sequence": "DWVDVANDLLRSCHVNQHIKHLSECGADVFVRLYESILGERVPDFIATPRSQEDDAHNVQAVIDSLALDYLQVSLSHITGENIVKGERESIRNLLEIFDGLLEYLTEEGSESSSQNGDETHVVPNSKIQVVSPEQLESNAGQLLPPLKLSSVDG", "length": 154, "header": "tr|A0A8V1AJF6-1|A0A8V1AC39_CHICK Computationally mapped isoform of Centrosomal protein 95 OS=Gallus gallus OX=9031 GN=CEP95 PE=4 SV=1 CANONICAL=A0A8V1AC39-1" }, "locus": { "chromosome": "18", "start_pos": 7531719, "end_pos": 7529368, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070874.1", "url": "https://www.ensembl.org/id/ENSGALT00010070874.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043565.1", "url": "https://www.ensembl.org/id/ENSGALP00010043565.1" } ] } }, { "isoform_ac": "A0A8V1AN32-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC39/entry#A0A8V1AN32-1", "sequence": { "sequence": "MGSAEGTDWVDVANDLLRSCHVNQHIKHLSECGADVFVRLYESILGERVPDFIATPRSQEDDAHNVQAVIDSLALDYLQVSLSHITGENIVKGERESIRNLLEIFDGLLEYLTEEGSESSSQNGDETHVVPNSKIQVVSPEQLESNAGQLLPPLKLSSVDGSQSECFVPLYDVDGLESTSELIQLGDTAHSFSERGEGSLESIQGAEVPKQHFSSSAQRLREPICQAVPLLPPFQPAEARSCDPVHRDHQSLDSQSAALVNSQELESPTLETQTSEGVSGALLSRKIPAGDKMVSNDAEDNVKVHVATSLSLWKLSQYENSTIDSLEEPLSHRTTKENLSKQELHQVSQKLSHRLNELDAMLKRALGGRTREEVTDEDNMSQHSDSVMDYRRRRAERDIPHLKYPSRTRSLSPSSPSTQHQRFSESGDILCSNGKGQVKKIHNKLQKEKDERTQEAKRVAKAYENELRIYEAQERLRLSKLREEVKELEQEYKENIFKESPKIPQPVKVYSRKTTPWNPRYSQWIPKRGTVKPKKAAPMKVRDDDLLVQLLEEFPHLHISQHTMNKMWRQQLAQTEQLKAASGRARLKLQNEVQQALKKHELLVAIIKKDRDHNKRLQEFKQRIYRQKWTQNKVREKRQQVARARKYYEDYRVQLRAKMMRARTREERIFKNLFEEGLEIQKQRLKDLRAYAQEMRAEQRREHQNELESMENYYRDQFSMLAEAVSRERQEIQTREKAQTQMLQKTKRELRSRMEKEIQQLQTAIMQNDDETFFQELEADRLRSRLQMASFQYNKSGFS", "length": 799, "header": "tr|A0A8V1AN32-1|A0A8V1AC39_CHICK Computationally mapped isoform of Centrosomal protein 95 OS=Gallus gallus OX=9031 GN=CEP95 PE=4 SV=1 CANONICAL=A0A8V1AC39-1" }, "locus": { "chromosome": "18", "start_pos": 7542092, "end_pos": 7529563, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070876.1", "url": "https://www.ensembl.org/id/ENSGALT00010070876.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043567.1", "url": "https://www.ensembl.org/id/ENSGALP00010043567.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "F1MLU4-1", "protein_name": "Centrosomal protein 95", "gene_name": "CEP95", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MVSRARKPPPRHVLPKEVLPPVTNQQREFVLTSLPFPPHPFPALSFASSPVSAGSAPCGPFRTPSRARRARSPEATCLRDMAGSEAEWITIANNLLLKCHIHLRIRELEDCDANVFIALYQSILGEKVPDLIAIPRNQEDDAHNVQAAIDSLALDYLQVSLSHITGENIVKGDKESIKNLLEIFDGLLEYLTEHVSETSHEKSETGQDSKESHRGDPLEDRENTKESRSSWKRVSFERCSLSSGALGSSWDGDEAESTGEIIRLGDTAHTFSLRSNGAQGPNEMQSKKPSTLPCSSSQEEEVLNPPSRFLSKSRTSFVEDKISSVDMIPSARKLGEPIRSAIPLHPPYHPSEPRAPCPIGKEYLRSSHCSPTMNSTGEGTAFSTEPDNRVSLSSKLSQDSKQEMYPAGDQGPRTRKLPREKRYENRAAVSSWDSTFSQRAGKRLTEQELHAVSEKLSQRLSELDSMLKSALGDRMKEKTGSEENIGNEEVGSGNDETLSQHSDGIVEYGPKKPRPGLAMHRKAPSRSHSLSPSPVNKNKQFQMERKKQRKPKETDVRRFQAKAITEAFEKELRRNKVQENIGPLGINDEEETEKIYREAVHKGTPKRSQPWKIYSRKTTTPSPRGGLPKPNKAVPMKVNEHSLLPLMLEQFPFLYVSGQTLSKMWKQQIAQVEQLKKDAYRENRSKKKLQDEIEEALRRHDLLTALIKKEYEHNKRLQDFKDRIHRQKLTQSKIKENRQQIVRARKYYDDYRVQLRSKMMRMRSREEMIFKKLFEEGLQIQKQRLRDLRNYAKEKRDEQKKQHQNELDSMENYYKDQFSLLAEAISQERQELKAREKSQAQMLYKVKRELRSKMEKEIQQLQYMITQGDDDAFFRELEAERFKCRLHLASFQYSKNPFL", "length": 899 }, "evidence": [ { "id": "A0A8V1AC39", "url": "https://omabrowser.org/oma/group/A0A8V1AC39/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "I3LTR6-1", "protein_name": "Centrosomal protein 95", "gene_name": "CEP95", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAGSEADWVTVANNLLLKCHIHLRIRELEDCDANVFIALYQSILGEKVPDLIAIPRSQEDEAHNVQAVIDSLALDYLQVSLSHITGENIVKGDKESIKNLLEIFDGLLEYLTEHSETSHEKSETGQSFKESHQGEPIEEPESTKESRSSWKRVSFERCSLSSEVLGPSWDGDEAESTGEIIRLGDTAHTFSLRSNGAQGTNEMQSKKDLTLPCSNSHEEVLNLPSSSFLSRSRTSFVEDPETPSVDMIPSAKKLGEPIRSAIPLHPPFHPSEPRAPCPIGKEYLRSSHCSPTMNSTGEGTAFSVEPENGVFLSSKLSKDNGQEMYPAQVQGSRTRKLPKGKRYENRAAVSSWDSPFPQRAGERLTEQELHAVSEKLSQRLSELDWMLKSALGDRVKEKTGCEEEDVGNGDLESGNDETLSQHSDSIMEYGPKKRRPGLAVHRKLPSRSHSLSPSPVNKNKQFHMQRKKQQKPKEADNRRFQAKAITEAFEKELRRNKVQENIGPLGINEEEETEKIYGETLHKETPKRSQPWKIYSRKTTSPSPRSGLPKPNNAVPMKVNEHSLLPLMLQQFPFLYVSGQTLSKMWKQQIAQVEQLKKDACRENRSKKKLQDEVEEALRRHDLLTALVKKEYEHNRRLQDFKDRIHRQKLTQSKIKENRQQIVRARKYYDDYRVQLRSKMMRMRTREEMIFKKLFEEGLQIQKQRLRDLRNYAREKRDEQKRQHQNELDSLENYYKDQFSLLAEAISQERQELKAREKSQAQVLHKAKRELRSKMEKEIEQLQNLITQNDDDAFFRELEAERFKSRLHLASFQYSKNPFL", "length": 820 }, "evidence": [ { "id": "A0A8V1AC39", "url": "https://omabrowser.org/oma/group/A0A8V1AC39/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q5XI03-1", "protein_name": "Centrosomal protein of 95 kDa", "gene_name": "Cep95", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASSEAEWVTIANNLLFKCHIHLRIHKLQDCDANVFIALYQSILGEKVPDLIVIPRSQEDNAHNVQAVIDSLALDYLQVSLSHITGENIVKGDKGSIKNLLEIFDGLLEYLTEHISESSHNRSASEQFCRDSRGEEPVEELESAKESSWRKVPFMRCSFSPDALGPTWDEEEAESTGEIIRLGDTAHTFSLRSNGAQNSMNFWSRKASTSGIRPPEEMLNPGLSSFLFKNGPTCEEEEAPPIHMATSARKLGEPIRAAIPLHPPYHPPEPRAPCPIGKEYLCSGHYLSTPASGEHRAPSVEPGDVFLTSTLCKDDDQETDLDLTESSKTRRLSKGERSENRAVAPSEYPPFPQKARKRLTEQELHAMSEKLSQRLSELDWMLKTALGDRATGEAHGKDGGAGDEEAHSANEEMLSQHSDSVMEYGPRKPRPGFSMHRKAPYRSHSLSPSSVNKHRQSEKERKKQHKSKGTDTHHFQAKALTEAFERELRKNKVQENVGLRGIREEEEETEKSYKEAFAKGTTKQSQVQKIYSRKTAAPTPKGGLLKSSKASPMKVNEHSLLSLMLEQFPFLYVSDPTLTKMWKQQMAQVEQLRREAQRENRSKKKLQDEIEEALRRHDLLTALVKKEYDHNKRLQDFKDRIHKQRLTQSKIKENRHQSVRARKYYDDYRVQLRAKMMKMRTREEMIFKKLFEEGLQIQKQRLRDLRNYAKEKRSEEKRQHQNELDSMENYYKDQFSLLAEAISQGRQELKARQRSQAQTLHKVKRELRAKMEKEIEQLQHLITQSDDDAFFRELEAERFKARLQLASFQYSKNPFPRGQTP", "length": 821 }, "evidence": [ { "id": "A0A8V1AC39", "url": "https://omabrowser.org/oma/group/A0A8V1AC39/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8BVV7-1", "protein_name": "Centrosomal protein of 95 kDa", "gene_name": "Cep95", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASSEAEWVTIANNLLFKCHIHLRIHELQDCDANVFIALYQSILGEKVPDLIVLPRNQEDEAHNVQAVIDSLALDYLQVSLSHITGENIVKGDNESIRNLLEIFDGLLDYLTEHISESSPNKSETEQYSKDSHGEEAGEDLERTEEAKWRNASFMRCSFSSDTLGPTWDEDEAESTGEIIRLGDTAHTFSQRSNGAQNSKDLRSRKASASPGVEPPEEMLNPGPLGFLSQNGPPCEAASETPPMSMVPSARKLGEPIRAAIPLHPPYHPSEPRAPCPIGKEYLWSSRYLSTPTSGEHMAPSVEPDDAFLTSTLFKDDDQETYLPKPEATRTRKPSKGERDENRAAIPSEHLPFSQKARKPLTEQELHAMSEKLSQRLSELDWMLKTALGDRGTGETDGNDGDGGGEEVRSGNEEMLSQHSDSVMEYGPKKPRPGFSTCRKAPYRSHSLSPSSVNKHRQLEKEKKRQHKSKGTDSCHFQAKALTEAFERELRKHKVQENVGLRGIREEEEEEEETGKSYREVVPKGTSKRSQVQKTYSRKTAAPSPKGDGRLKSSKASPMKVSEHSLLSLMLEQFPFLYVSDPTLTKMWKQQMAQVEQLKREAQRENRSKKKLQDEIEEALRRHDLLTALVKKEYDHNKRLQDFRDRIQRQRLTQSKIKENRHQSVRARKYYDDYRVQLRAKMMKMRTREEMIFKKLFEEGLQIQKQRLRDLRNYAKEKRNEEKRQHQNELDSMENHYKDQFSLLAEAISQERQELKVRQKFQAQTLHKVKRELRAKMEKEIQQLQHMITQNDDDAFFRELEAERFKARLQLASFQYSKNPFPRGQTS", "length": 827 }, "evidence": [ { "id": "A0A8V1AC39", "url": "https://omabrowser.org/oma/group/A0A8V1AC39/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96GE4-1", "protein_name": "Centrosomal protein of 95 kDa", "gene_name": "CEP95", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAGSDAEWVTIANNLLFKCHIHLRIHELQDCDANVFIALYQSILGEKVPDLIVIPRSQEDDAHNVQAVIDSLALDYLQVSLSHITGENIVKGDKESIKNLLEIFDGLLEYLTERISETSHEKSETEQYFKESDRGERLEEPESTKESKSSWKRVSFGRCSLSSEMLGPSWDGDEAESTGEIIRLGDTAHTFSLRSNGAQCPNEMLSKKALASPSSKSHEDMLYPPSVLSKSRTSFVEDTETLSVSGIPNARKLGEPIRAAIPLHPPYHPSEPRAPCPIGKEYLHSSHCSPAVNSTGEHTEFSGDLDDGLFLISKLPKGSKWEVYPAQVQGPRTRKPPKGKRNENRATASSCNSPFPQRPRKRLTEQELHDVSEKLSQRLSELDWMLKSALGDRIKEKTDHKEENTGNEEVEDGTEETLSQHSDGIVEYGPKKSRPGLSMRRKPPYRSHSLSPSPVNKHKQFHLERKRQRKPRETDVRQFQAQAFTEAFERELRRHKVQENIGPLRIHEKEEETEKIYRGEAVRKGTPECSQPWKIYSRKTTTQSLRGGLPKPNKAVPMKVSEHSLLPLMLEQFPFLYVSGPTLSKMWKQQIAQVEQLKKEACRENRSKKKLQDEIEEALRRHDLLTTLVKKEYEHNKRLQDFKDCIRRQRLTQSKIKENRQQIVRARKYYDDYRVQLCAKMMRMRTREEMIFKKLFEEGLNIQKQRLRDLRNYAKEKRDEQRRRHQDELDSMENYYKDQFSLLAEAISQEHQELKAREKSQAQTLHKVKRELRSKMEKEIQQLQDMITQNDDDVFFRELEAERFRSRLQLASFQYSKSPSL", "length": 821 }, "evidence": [ { "id": "A0A8V1AC39", "url": "https://omabrowser.org/oma/group/A0A8V1AC39/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "spindle pole", "id": "GO:0000922", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000922", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AC39", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC39" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AC39", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC39" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 347, "end_pos": 349, "annotation": "n_glycosylation_sequon" }, { "start_pos": 365, "end_pos": 367, "annotation": "n_glycosylation_sequon" }, { "start_pos": 406, "end_pos": 408, "annotation": "n_glycosylation_sequon" }, { "start_pos": 821, "end_pos": 823, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AC39", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC39" }, { "id": "PF19016", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19016" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DUF5745", "eco_id": "ECO_0000259", "start_pos": 50, "end_pos": 108, "start_aa": "Pro", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 347, "end_pos": 349 }, { "start_pos": 365, "end_pos": 367 }, { "start_pos": 406, "end_pos": 408 }, { "start_pos": 821, "end_pos": 823 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AC48-1", "uniprot_ac": "A0A8V1AC48", "uniprot_id": "A0A8V1AC48_CHICK", "mass": { "chemical_mass": 85824.0, "monoisotopic_mass": 85824.0 }, "refseq": { "ac": "XP_015148335", "name": "semaphorin-3G", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015148335" }, "gene_names": [ { "name": "SEMA3G", "type": "recommended", "evidence": [ { "id": "A0A8V1AC48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC48" } ] }, { "name": "SEMA3G", "type": "synonym", "evidence": [ { "id": "XP_015148335", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015148335" } ] } ], "protein_names": [ { "name": "Semaphorin 3G", "type": "synonym", "evidence": [ { "id": "A0A8V1AC48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC48/entry#names_and_taxonomy" } ] }, { "name": "semaphorin-3G", "type": "synonym", "evidence": [ { "id": "XP_015148335", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015148335" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052543.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015148335.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015148335", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015148335" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AC48", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC48" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SEMA3G", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC48", "locus": { "chromosome": "12", "start_pos": 3303119, "end_pos": 3310709, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027513", "url": "https://www.ensembl.org/id/ENSGALG00010027513" } ] } } ], "crossref": [ { "id": "A0A8V1AC48", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AC48", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd05871", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05871", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "415945", "url": "https://www.ncbi.nlm.nih.gov/gene/415945", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001627", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001627", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016201", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016201", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027231", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027231", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036352", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036352", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041416", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041416", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:415945", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415945", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DLQAMYL", "url": "https://omabrowser.org/oma/group/DLQAMYL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AC48", "url": "https://www.orthodb.org/?gene=A0A8V1AC48", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AGU0", "url": "https://www.orthodb.org/?gene=A0A8V1AGU0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11036", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11036", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11036:SF20", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11036:SF20", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01403", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01403", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18452", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18452", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015148335", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015148335", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AC48", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC48", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AC48-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC48-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGU0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGU0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGU0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGU0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRAAAALGWLWGALLAAGSSPPRLRLPYRELLGMNRSVLFFGHRGFLGFRSLYLDEYRDRLFIGGKDVLYSLRLDRASADTKEIYWPPLPGQTEECFRKGKDPATDCANYVRLLQPYNRTHLLACGTGACHPVCTFIYVGHRGETQHAFILDPGSTESGRGRCPHEPDRAFASTIIGGELYAGLTADFLGRDPGIFRSTGTRAALRTEVDQRLLNDPKFVAAYMIPDNDDRDDDKAYFFFTEKVVEADSKEHTIVSRVARVCVNDAGGQRVLVNKWSTFNKARLVCSVPGPGGIDTYFDELEDVFLLRTKDGKNPEIYALFSTVSHVFQGSAVCVYRMADIREVFNGPFAHRDSPLHQWGAYEGRVPYPRPGVCPSKTTNQPRRPYSSTKELPDEVLHFARAHPLMYRAVRPRHHRPLLVKTDLQQRLLQLVVDRVDTEDGQHDVLFLGTDAGSVLKVVVLQMQSSAVTEEVVLEELQVFKVPVPITQMEISVKRQKLYVGASLGVAQVRLHQCKSYGTACAECCLARDPYCAWDGTACTRYQPSGKRRHVRHTSSVHQCLDQNLTVDDLEHVEEKVLYGMEHNSTFLECVPRSPQASVQWFVQRPPDEQRDEVKTDERVLQTEQGLLFRQLHRRDAGVYYCKTLEHGFTQTVAKTALEVLGGEQLARATPRQREDRHPPCPEPWLAAPAPKTWYKDILHLASSADRQRVEEQCLRLWCGHRKGKMAKGKHALAGMDVVKKGRVAKPHGERIRVPRQAAAT", "length": 761, "header": "tr|A0A8V1AC48-1|A0A8V1AC48_CHICK Isoform 1 of Semaphorin 3G OS=Gallus gallus OX=9031 GN=SEMA3G PE=3 SV=1 CANONICAL=A0A8V1AC48-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AC48-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC48/entry#A0A8V1AC48-1", "sequence": { "sequence": "MRAAAALGWLWGALLAAGSSPPRLRLPYRELLGMNRSVLFFGHRGFLGFRSLYLDEYRDRLFIGGKDVLYSLRLDRASADTKEIYWPPLPGQTEECFRKGKDPATDCANYVRLLQPYNRTHLLACGTGACHPVCTFIYVGHRGETQHAFILDPGSTESGRGRCPHEPDRAFASTIIGGELYAGLTADFLGRDPGIFRSTGTRAALRTEVDQRLLNDPKFVAAYMIPDNDDRDDDKAYFFFTEKVVEADSKEHTIVSRVARVCVNDAGGQRVLVNKWSTFNKARLVCSVPGPGGIDTYFDELEDVFLLRTKDGKNPEIYALFSTVSHVFQGSAVCVYRMADIREVFNGPFAHRDSPLHQWGAYEGRVPYPRPGVCPSKTTNQPRRPYSSTKELPDEVLHFARAHPLMYRAVRPRHHRPLLVKTDLQQRLLQLVVDRVDTEDGQHDVLFLGTDAGSVLKVVVLQMQSSAVTEEVVLEELQVFKVPVPITQMEISVKRQKLYVGASLGVAQVRLHQCKSYGTACAECCLARDPYCAWDGTACTRYQPSGKRRHVRHTSSVHQCLDQNLTVDDLEHVEEKVLYGMEHNSTFLECVPRSPQASVQWFVQRPPDEQRDEVKTDERVLQTEQGLLFRQLHRRDAGVYYCKTLEHGFTQTVAKTALEVLGGEQLARATPRQREDRHPPCPEPWLAAPAPKTWYKDILHLASSADRQRVEEQCLRLWCGHRKGKMAKGKHALAGMDVVKKGRVAKPHGERIRVPRQAAAT", "length": 761, "header": "tr|A0A8V1AC48-1|A0A8V1AC48_CHICK Isoform 1 of Semaphorin 3G OS=Gallus gallus OX=9031 GN=SEMA3G PE=3 SV=1 CANONICAL=A0A8V1AC48-1" }, "locus": { "chromosome": "12", "start_pos": 3310694, "end_pos": 3303361, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066645.1", "url": "https://www.ensembl.org/id/ENSGALT00010066645.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040805.1", "url": "https://www.ensembl.org/id/ENSGALP00010040805.1" } ] } }, { "isoform_ac": "A0A8V1AGU0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC48/entry#A0A8V1AGU0-1", "sequence": { "sequence": "MRAAAALGWLWGALLAAGSSPPRLRLPYRELLGMNRSVLFFGHRGFLGFRSLYLDEYRDRLFIGGKDVLYSLRLDRASADTKETDCANYVRLLQPYNRTHLLACGTGACHPVCTFIYVGHRGETQHAFILDPGSTESGRGRCPHEPDRAFASTIIGGELYAGLTADFLGRDPGIFRSTGTRAALRTEVDQRLLNDPKFVAAYMIPDNDDRDDDKAYFFFTEKVVEADSKEHTIVSRVARVCVNDAGGQRVLVNKWSTFNKARLVCSVPGPGGIDTYFDELEDVFLLRTKDGKNPEIYALFSTVSHVFQGSAVCVYRMADIREVFNGPFAHRDSPLHQWGAYEGRVPYPRPGVCPSKTTNQPRRPYSSTKELPDEVLHFARAHPLMYRAVRPRHHRPLLVKTDLQQRLLQLVVDRVDTEDGQHDVLFLGTDAGSVLKVVVLQMQSSAVTEEVVLEELQVFKVPVPITQMEISVKRQKLYVGASLGVAQVRLHQCKSYGTACAECCLARDPYCAWDGTACTRYQPSGKRRHVRHTSSVHQCLDQNLTVDDLEHVEEKVLYGMEHNSTFLECVPRSPQASVQWFVQRPPDEQRDEVKTDERVLQTEQGLLFRQLHRRDAGVYYCKTLEHGFTQTVAKTALEVLGGEQLARATPRQREDRHPPCPEPWLAAPAPKTWYKDILHLASSADRQRVEEQCLRLWCGHRKGKMAKGKHALAGMDVVKKGRVAKPHGERIRVPRQAAAT", "length": 740, "header": "tr|A0A8V1AGU0-1|A0A8V1AC48_CHICK Computationally mapped isoform of Semaphorin 3G OS=Gallus gallus OX=9031 GN=SEMA3G PE=3 SV=1 CANONICAL=A0A8V1AC48-1" }, "locus": { "chromosome": "12", "start_pos": 3310694, "end_pos": 3303361, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066648.1", "url": "https://www.ensembl.org/id/ENSGALT00010066648.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040807.1", "url": "https://www.ensembl.org/id/ENSGALP00010040807.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:415945", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415945", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1LNH0-1", "protein_name": "Semaphorin 3G", "gene_name": "Sema3g", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MARCSAWAICCLLGSLLFHMGSPNPGPSTSVPRLRLSYRDLLTTNRSAIFLGPRGSLDLQVMYLDEYRDRLFLGGRDALYSLRLDQAWPDPREVLWPPQPGQKVECVRKGKDPLTECANFVRVLQPHNRTHLLACGTGAFQPICTFITVGHRGEHVLHLDPSSIENGRGRCPHEPSRPFASTFVGGELYTGLTADFLGREAMIFRSGGPRPALRSDSDQSLLHDPRFVMAARIPDNSDRDDDKVYFFFSETVPSPDGGPGHVTVSRVGRVCVNDAGGQRVLVNKWSTFLKARLVCSVPGPGGAETHFDQLEDVFLLWPKAGKNLEVYALFSTVSAVFRGFAVCVYHMVDIWEVFNGPFAHRDGPQHQWGPYGGKVPFPRPGVCPSKMTAQPGRPFGSTKDYPDEVLQFVRGHPLMFQPVRPRRGRPVLVKTHLAQQLCQIVVDRVEAEDGTYDVIFLGTDSGSVLKIIALQGSGLPEPEEVVLEELQVFKVPTPITEMEISVKRQTLYVGSPLGVARLQLHQCETYGSACAECCLARDPYCAWDGTSCARYRPSSGKRRFRRQDIRHGNPAVQCLGQGQSQDKASGLVTRVFGTEHNSTFLECRPKSPQAAVRWFLQRPGDKGADQVKTDERVVQTDQGLLFRRLSRLDAGNYTCTTLEHGFSQTVVRFALEVIAAVQLDSLFLREPRLEEPSAWRSVASASPKTWYKDILQLTGFANLPRVDEYCERVWCRGVGERSGSFRGKGKQAKGKSWAGLELGRKMKSRVQAEHNRTPREVEAT", "length": 780 }, "evidence": [ { "id": "A0A8V1AC48", "url": "https://omabrowser.org/oma/group/A0A8V1AC48/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1SIW2-1", "protein_name": "Semaphorin 3G", "gene_name": "SEMA3G", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAPSAWAICCLLGGLLLHGGSPSPGPSVPRLRLSYRDLLSVNRSAIFLGPRGSLDLRALYLDEYRDRLFLGGRDAIYSLRLDQAWPDAREVLWPPQPGQREECVHKGRDPLVECANFVRVLQPHNRTHLLACGTGAFQPTCALIAVGHRGEHVLHLEPYSVESGRGRCPHEPSRPFASTFVGGELYTGLNADFLGREAMIFRSGGPRPALRSDSDQNLLHDPRFVMAARIPDNSDQDDDKVYFFFSETVPSPDGGLSRVTVSRVGRVCMNDMGGQRVLVNKWSTFLKARLLCSVPGPGGAETHFNQLEDVFLLWPSAGKSLEVYALFSMVSTVFQGYAVCVYHMADIWEVFKGPFAHQDGPQHQWRPYGGKVPFPRPGMCPSKMTSQPGRPFGSTKDYPDEVLQFARAHPLMFRPVRPWRDRPVLVKTHLAQQLRQIVVDRVEAEDGTYDVIFLGTDSGSVLKVIALQEGSAEPEEVVLEELQVFKVPTPITEMEISVKRQMLYVGSRLGVAQLQLHQCETYGSACAECCLARDPYCAWDGASCTRYRPGTSKRRIRRQDIRHGNPALQCLGQSQDEEAAGLVAATTVYGTEHNSTFLECLPKSPQATVHWFLQSRGDEGPNQVKTDERVLQTEQGLLFRRLNRLDAGTYTCMTLEHGFSQVVVRLALEVIVATQLNTLFPRGLRPEEPATREGLASTPSKAWYKDILQLIGFANLPRVDEYCERVWCPSRSRSRSKQAKGKNWVGLELGKKVKSRVQAERNRTPREVEAT", "length": 771 }, "evidence": [ { "id": "A0A8V1AC48", "url": "https://omabrowser.org/oma/group/A0A8V1AC48/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3MYK9-1", "protein_name": "Semaphorin 3G", "gene_name": "SEMA3G", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAPSAWAVCCLLGGLLLRGGSPNPGPSVPRLRLSFRDLLSANRSAIFLGPRGSLDLQALYLDEYRDRLFLGGRDAIYSLRLDQTWPDPREVLWPPQPGQREECVHKGRDPLVECANFVRVLHPHNRTHLLACGTGAFQPTCALLAVGHRGEHVLHLEPRSMESGRGRCPHEPSRPFASTFVGGELYTGLNADFLGHEAMIFRSGGPRPALRSDSDQNLLHDPRFVLAARIPDNSDPDDDKVYFFFSETVPSPDGGPGRVTISRVGRVCVNDAGGQRVLVNKWSTFLKARLLCSVPGPGSAETHFDQLEDVFLLWPNSGKSLEVYALFSTVSAVFQGYAICVYHMADIWEVFKGPFAHQDGPQHQWGPYGGKVPFPRPGMCPSKMTAQPGRPFGSTKDYPDEVLQFARAHPLMFRPVRPRRGRPVLVKTHLAQQLRQIVVDRVEAEDGTYDVIFLGTDSGSVLKVIALQGAGSAEPEEVVLEELQVFKVPTPITEMEISVKRQMLYVGSRLGVARLQLHQCETYGSACAECCLARDPYCAWDGASCTRYRPGSNKRRFRRQDIRHGNPALQCLGQSQEEETAGLVATTTVYGTEHNSTFLECLPKSPQAAAHWFLQRPGDERPEQQVKTDERVLQTEQGLLFRRLNRLDAGTYTCMTLEHGFSQVVVRLALEVIVPAQLDILFPRETRPEEPTARGGPTSPYSKAWYKDIMQLIGFANLPRVDEYCERVWCPSRSRTRGKQAKGKSWVGLELGKKVKSRVQAERNRTPREV", "length": 770 }, "evidence": [ { "id": "A0A8V1AC48", "url": "https://omabrowser.org/oma/group/A0A8V1AC48/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q4LFA9-1", "protein_name": "Semaphorin-3G", "gene_name": "Sema3g", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDPSAWAICCLLGSLLFHVGIPSPGPSPSVPRLRLSYRDLLSTNRSAIFLGPRGSLDLQVMYLDEYRDRLFLGSRDALYSLRLDQAWPDPREVLWLPQPGQKVECVRKGKDPLTECANFVRVLQPHNRTHLLACGTGAFQPICTFITVGHRGEHVLRLDASSVENGRGRCPHEPSRPFASTFVGGELYTGLTADFLGREAMIFRSGGPRPALRSDSDQSLLHEPRFVMAARIPDNSDRDDDKVYFFFSETVPSPDGGPGHVTISRVGRVCVNDAGGQRVLVNKWSTFLKARLVCSVPGPGGAETHFDQLEDVFLLWPKAGKSLEVYALFSTVSAVFQGFAVCVYHMVDIWEVFNGPFAHRDGPQHQWGPYGGKVPFPRPGVCPSKMTAQPGRPFGSTKDYPDEVLQFVRDHPLMFQPVRPRRGRPVLVKTHLAQRLRQIVVDRVEAEDGTYDVIFLGTDSGSVLKVIALQGGGLTEPEEVVLEELQVFKVPTPITEMEISVKRQTLYVGSPLGVARLQLHQCETYGSACAECCLARDPYCAWDGTACARYRPSSGKRRFRRQDIRHGNPAVQCLGQGQSQNKAASGLMTRVFGTEHNSTFLECLPKSPQAAVRWFLQRPGDKGTDQVKTDERVVQTAQGLLFRRLSRHDAGNYTCTTLEHGFSQTVVRFALEVIAAVQLDSLFLRESRLEEPSAWGSLASASPKTWYKDILQLTGFANLPRVDEYCERVWCRGVGERSGSFRGKGKQAKGKSWAGLELGKKMKSRVLAEHNRTPREVEAT", "length": 780 }, "evidence": [ { "id": "A0A8V1AC48", "url": "https://omabrowser.org/oma/group/A0A8V1AC48/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NS98-1", "protein_name": "Semaphorin-3G", "gene_name": "SEMA3G", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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"categories": [ "Genome Annotation" ] }, { "id": "IPR026236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029321", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029321", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:417640", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417640", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "IISNYPH", "url": "https://omabrowser.org/oma/group/IISNYPH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AC67", "url": "https://www.orthodb.org/?gene=A0A8V1AC67", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1P1Z0", "url": "https://www.orthodb.org/?gene=F1P1Z0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR28608", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28608", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR28608:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28608:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14750", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14750", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1AC67", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC67", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AC67-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC67-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1P1Z0", "url": "https://www.uniprot.org/uniprotkb/F1P1Z0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1P1Z0-1", "url": "https://www.uniprot.org/uniprotkb/F1P1Z0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAECSGLQFVSPYAFEAMQKVDVVRLAALSDPELRLLLPCLVRMALCAPADQSQSWAQDKKLILRLLSGVEAVNSIVALLSVDFHALEQDASKEQQLRHKLGGGSGESILVSQLQHGLTLEFEHSDSPRRLRLVLSELLAIMNKVSESNGEFFLKSSELFESPVYLEEAADVLCILQAELPSLLPIVDVAEALLHVKNGAWFLCLLVANVPDSFNEVCRGLIKNGERQDEESVGGRRRTEALRHLCKMNPSQALRVRGMVVEECHLPGLGVALTLDHTKNESSDDGVSDLVCFVSGLLLGTNAKVRTWFGTFIRNGQQRKRDNISSVLWQMRRQLLLELMGILPTVRSTHIVEEADVDTEPNVSVYSGLKEEHVVKASALLRLYCALMGIAGLKPTDEEAEQLLQLMTSRPPATPAGVRFVSLSFCMLLAFSTLVSTPEQEQLMVMWLSWMIKEEAYFESISGVSASFGEMLLLVAMYFHSNQLSAIIDLVCSTLGMKIVIKPSSLSRMKTIFTQEIFTEQVVTAHAVRVPVTGSLSANITGFLPIHCIYQLLRSRSFTKHKLFVIITAHYQQQMWLFSLCETTTPLHPQLLPLIDVYINSILTPASKSNPEATNQPVTEQEILNVFQGLTGGENTRPAQRYSITTQLLVLYYVLSYEEALLANTKILAAMQRKPKSYSSALMDQIPIKYLIRQAQGLQQELGGLHSALLRLLATNYPHLCIVEDWICEEQITGTDSLLRRMLLTTIAKNHSPKQLQEAFSMLPGNHTQLMQILEHLTLLSAGELIPYAEVLTSNMNCLLNAGVPRRILQTVNKLWMVLNTVMPRRLWVMTVNALQPSVKIVRQQKYTQNDLMIDPLIVLRSKSPPLMDITLHMLNGYLLASKAYLNAHLKETAEQDIRPSQNNAMGPETPEVTREELKNALLAAQDSAAVQILLEICLPTEEEKAQSSSTYSLLKSVQSTTSPKSSDVEEEEDSLLCNLREVQCLICCLLHQMYIADPNIVKLVHFQGYPCELLALTVAGIPSMHICLDFIPELIAQPELEKQIFAIQLLSFLCIQYALPKSLSVARLAINVMGTLLTVLTQSKRYAFFMPTLPCLVSFCQAFPPLYEDIMSLLIQIGQVCASDVATQTRDFDPIITRLQQLKERPNEVSGLCKDSPYKSCSRDITSVDPDVQLCQCVESTIIEIINMSVSGV", "length": 1194, "header": "tr|A0A8V1AC67-1|A0A8V1AC67_CHICK Isoform 1 of Integrator complex subunit 2 OS=Gallus gallus OX=9031 GN=INTS2 PE=3 SV=1 CANONICAL=A0A8V1AC67-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AC67-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC67/entry#A0A8V1AC67-1", "sequence": { "sequence": "MAECSGLQFVSPYAFEAMQKVDVVRLAALSDPELRLLLPCLVRMALCAPADQSQSWAQDKKLILRLLSGVEAVNSIVALLSVDFHALEQDASKEQQLRHKLGGGSGESILVSQLQHGLTLEFEHSDSPRRLRLVLSELLAIMNKVSESNGEFFLKSSELFESPVYLEEAADVLCILQAELPSLLPIVDVAEALLHVKNGAWFLCLLVANVPDSFNEVCRGLIKNGERQDEESVGGRRRTEALRHLCKMNPSQALRVRGMVVEECHLPGLGVALTLDHTKNESSDDGVSDLVCFVSGLLLGTNAKVRTWFGTFIRNGQQRKRDNISSVLWQMRRQLLLELMGILPTVRSTHIVEEADVDTEPNVSVYSGLKEEHVVKASALLRLYCALMGIAGLKPTDEEAEQLLQLMTSRPPATPAGVRFVSLSFCMLLAFSTLVSTPEQEQLMVMWLSWMIKEEAYFESISGVSASFGEMLLLVAMYFHSNQLSAIIDLVCSTLGMKIVIKPSSLSRMKTIFTQEIFTEQVVTAHAVRVPVTGSLSANITGFLPIHCIYQLLRSRSFTKHKLFVIITAHYQQQMWLFSLCETTTPLHPQLLPLIDVYINSILTPASKSNPEATNQPVTEQEILNVFQGLTGGENTRPAQRYSITTQLLVLYYVLSYEEALLANTKILAAMQRKPKSYSSALMDQIPIKYLIRQAQGLQQELGGLHSALLRLLATNYPHLCIVEDWICEEQITGTDSLLRRMLLTTIAKNHSPKQLQEAFSMLPGNHTQLMQILEHLTLLSAGELIPYAEVLTSNMNCLLNAGVPRRILQTVNKLWMVLNTVMPRRLWVMTVNALQPSVKIVRQQKYTQNDLMIDPLIVLRSKSPPLMDITLHMLNGYLLASKAYLNAHLKETAEQDIRPSQNNAMGPETPEVTREELKNALLAAQDSAAVQILLEICLPTEEEKAQSSSTYSLLKSVQSTTSPKSSDVEEEEDSLLCNLREVQCLICCLLHQMYIADPNIVKLVHFQGYPCELLALTVAGIPSMHICLDFIPELIAQPELEKQIFAIQLLSFLCIQYALPKSLSVARLAINVMGTLLTVLTQSKRYAFFMPTLPCLVSFCQAFPPLYEDIMSLLIQIGQVCASDVATQTRDFDPIITRLQQLKERPNEVSGLCKDSPYKSCSRDITSVDPDVQLCQCVESTIIEIINMSVSGV", "length": 1194, "header": "tr|A0A8V1AC67-1|A0A8V1AC67_CHICK Isoform 1 of Integrator complex subunit 2 OS=Gallus gallus OX=9031 GN=INTS2 PE=3 SV=1 CANONICAL=A0A8V1AC67-1" }, "locus": { "chromosome": "19", "start_pos": 7965929, "end_pos": 7952443, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070900.1", "url": "https://www.ensembl.org/id/ENSGALT00010070900.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043591.1", "url": "https://www.ensembl.org/id/ENSGALP00010043591.1" } ] } }, { "isoform_ac": "F1P1Z0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC67/entry#F1P1Z0-1", "sequence": { "sequence": "MAECSGLQFVSPYAFEAMQKVDVVRLAALSDPELRLLLPCLVRMALCAPADQSQSWAQDKKLILRLLSGVEAVNSIVALLSVDFHALEQDASKEQQLRHKLGGGSGESILVSQLQHGLTLEFEHSDSPRRLRLVLSELLAIMNKVSESNGEFFLKSSELFESPVYLEEAADVLCILQAELPSLLPIVDVAEALLHVKNGAWFLCLLVANVPDSFNEVCRGLIKNGERQDEESVGGRRRTEALRHLCKMNPSQALRVRGMVVEECHLPGLGVALTLDHTKNESSDDGVSDLVCFVSGLLLGTNAKVRTWFGTFIRNGQQRKRDNISSVLWQMRRQLLLELMGILPTVRSTHIVEEADVDTEPNVSVYSGLKEEHVVKASALLRLYCALMGIAGLKPTDEEAEQLLQLMTSRPPATPAGVRFVSLSFCMLLAFSTLVSTPEQEQLMVMWLSWMIKEEAYFESISGVSASFGEMLLLVAMYFHSNQLSAIIDLVCSTLGMKIVIKPSSLSRMKTIFTQEIFTEQVVTAHAVRVPVTGSLSANITGFLPIHCIYQLLRSRSFTKHKVSIKDWIYRQLCETTTPLHPQLLPLIDVYINSILTPASKSNPEATNQPVTEQEILNVFQGLTGGENTRPAQRYSITTQLLVLYYVLSYEEALLANTKILAAMQRKPKSYSSALMDQIPIKYLIRQAQGLQQELGGLHSALLRLLATNYPHLCIVEDWICEEQITGTDSLLRRMLLTTIAKNHSPKQLQEAFSMLPGNHTQLMQILEHLTLLSAGELIPYAEVLTSNMNCLLNAGVPRRILQTVNKLWMVLNTVMPRRLWVMTVNALQPSVKIVRQQKYTQNDLMIDPLIVLRCDQRVHRSPPLMDITLHMLNGYLLASKAYLNAHLKETAEQDIRPSQNNAMGPETPEVTREELKNALLAAQDSAAVQILLEICLPTEEEKAQSSSTYSLLKSVQSTTSPKSSDVEEEEDSLLCNLREVQCLICCLLHQMYIADPNIVKLVHFQGYPCELLALTVAGIPSMHICLDFIPELIAQPELEKQIFAIQLLSFLCIQYALPKSLSVARLAINVMGTLLTVLTQSKRYAFFMPTLPCLVSFCQAFPPLYEDIMSLLIQIGQVCASDVATQTRDFDPIITRLQQLKERPNEVSGLCKDSPYKSCSRDITSVDPDVQLCQCVESTIIEIINMSVSGV", "length": 1192, "header": "tr|F1P1Z0-1|A0A8V1AC67_CHICK Computationally mapped isoform of Integrator complex subunit 2 OS=Gallus gallus OX=9031 GN=INTS2 PE=3 SV=1 CANONICAL=A0A8V1AC67-1" }, "locus": { "chromosome": "19", "start_pos": 7965929, "end_pos": 7952443, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070901.1", "url": "https://www.ensembl.org/id/ENSGALT00010070901.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043592.1", "url": "https://www.ensembl.org/id/ENSGALP00010043592.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 414, "start_aa": "Thr", "end_pos": 414, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr414", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:417640", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417640", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A096MJ28-1", "protein_name": "BRCA1 interacting helicase 1", "gene_name": "Ints2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MMPECTSLQFVSPCAFEAMQKVDVVRLASLSDPELRLLLPCLVRMALCAPADQSQSWAQDKKLILRLLSGVEAVNSIVALLSVDFHALEQDASKEQQLRHKLGGGSGESILVSQLQHGLTLEFEHSDSPRRLRLVLSELLAIMNKVSECSGEFFFKSSELFESAVYLEEAADVLCILQAELPSLLPIVDVAEALLHVRNGAWFLCLLVANVPDSFNEVCRGLIKNGERQDEESLGGRRRTDALRFLCRMNPSQALKVRGMVVEECHLPGLGVALTLDHTKTEACEDGVSDLVCFVSGLLLGTNAKVRTWFGTFIRNGQQRRRENSGSVLWQMRRQLLLELMGILPTVRSTRIVEEADVEMEPTVSVYSGLKEEHVVKASALLRLYCALMGIAGLKPTEEEAEQLLQLMTSRPPATPAGVRFVSLSFCMLLAFSTLVSTPEQEQLMVVWLSWMIKEEAYFESTSGVSASFGEMLLLVAMYFHSNQLSAIIDLVCSTLGMKIVIKPSSLSRMKTIFTQEIFTEQVVTAHAVRVPVTSNLSANITGFLPIHCIYQLLRSRSFTKHKVSIKDWIYRQLCETSTPLHPQLLPLIDVYINSILTPASKSNPEATNQPVTEQEILNIFQEVIGGDSVRLNQRFSITAQLLVLYYILSYEEALLANTKTLASMQRKPKSYSSSLMDQIPIKFLIRQAQGLQQELGGLHSALLRLLATNYPHLCIVDDWICEEEITGTDALLRRMLLTSNAKTHSPKQLQEAFSAVPVSHTQVMQIMEHLTLLSASELIPYAEVLTSNMNQLLNSGVPRRILQTVNKLWMVLNTVMPRRLWVMTVNALQPSIKFIRQQKYTQNDLMIDPLIVLRCDRRVHRCPPLMDVTLHMLNGYLLASKAYLSAHLKETAEQDRPSPNNTVGLVGQTDAPEVTREELKNALLAAQDSAAVQILLEICLPTEEEKAKAANSDISLRNTQGVITIGTPNKDTEEGEDSLLCNLREVQCLICCLLHQMYIADPNIAKLVHFQGYPCELLPLTVAGIPSMHICLDFIPELIAQPELEKQIFAIQLLSHLCIQYALPKSLSVARLAVNVMGTLLTAVLTQAKRHSFFMPTLPSLVSFCRAFPPLYEDVMSLLVQIGQVCASDVATQTRDIDPIITRLQQIKEKPSGWSQIYKDASYKHGSRDTGSMDPDVQLCHCIESTVIEIINMSVSGI", "length": 1199 }, "evidence": [ { "id": "A0A8V1AC67", "url": "https://omabrowser.org/oma/group/A0A8V1AC67/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E9QC62-1", "protein_name": "Integrator complex subunit 2", "gene_name": "ints2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTDSASLQFVSPYAFEAMQKVDVARLAALSDPELRLLLPCLVRMALCAPADQSNAWAQDKKLILRLLSGVEAVNSIVALLSVDFHALEQDARKEQQLRHKAGGSNGESILVSQLQHGLTLEFEHSDPLRRLRLALSELLAIMNKVADSNGEFFLKSSELFESPVYLEEVADVLCILQAELPSLLPIIEVAEALLHVRNGEWFLCLLVANVPDSFNEVCRGLIKNGERQDEESVGGRRRTEALRQLCQMNPSQALNIRAMVVEECHLPGLGVALTLDYKPDMADEAVSPLVSYVSGLLLGTNGKVRTWFSLFIRNGQQRKRESSSVLWQMRRQLLLELVAILPRSRSTHVPNDSDMDTESSSGYSGLREEHVVKASALLRLYCALMGIAGLRPTDEEAEQLLQLMTSRPPATPAGVRFVSLSFCKLLAFPTLVSTPEQEQLMVMWLSWMIKEEEYFESAAGVSASFGEMLLLVAMYFHSNQLSAIIELVCSTLGMKIAIKPSSLSKMKTIFTQEIFTEQVVTAHAVRVAVTNNLSANITGFLPIHCIYQLLRSRAFTKHKVSIKDWIFRQLCETTTPLHTQLLPLIDVYINSILTPASKTNPEATNQPITEQEILNVFQGLAGGDGGKVRSQYTITTQLLILYYILSYEEALLANTKTLALMQKKPKSYSAALMDQIPIKHLIRQAQGLQQELGVLHSALLRLLATNYPHLCMVEDWISEEEVTGTLPLLRKMLLTSSSCKYSQAQLREAFQNVLSGGPRLLRILEHLTLLSAGDLIPYAEALTANMGLLLEDTVSRRILQTVNKLWMVLNTVMPRRLWVMTVNALQSSVKLLRQQRYTQNDLMVDPLIVLRCDPRVFRCPPLMDITLHMLNGYLLASKAYLNAHLKETAEFERQAQTVSNLGLSGQPDTPEVTREELKNALLAAQDSAAVQILLEVCLASPQEELQLSGGGAGDSLLRCIQSAPGFPMRRQVGDTGAQGGRKAEGGLLSDLREVQCLICCLLHQMFIADPNIAKLVHFQGYPQPLLPLTVAGIPSMHICLDFIPELLAQPQLEKQIFAIQLLSHLCTQYALPKSLSVARLAISVMGTLLTVLTRAKRFAFFMPTLSCLVSFCKAFPPLFDDAMSLLVQVGQVSAADVTTKARDIDPFITRLQYLKEKPQEIAPSESKLCLPKRSAEELSRADPDVQLCYQIEATFMDIISSSTQAL", "length": 1206 }, "evidence": [ { "id": "A0A8V1AC67", "url": "https://omabrowser.org/oma/group/A0A8V1AC67/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q80UK8-1", "protein_name": "Integrator complex subunit 2", "gene_name": "Ints2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTPEGTGLQFVSPFAFEAMQKVDVVRLASLSDPELRLLLPCLVRMALCAPADQSQSWAQDKKLILRLLSGVEAVNSIVALLSVDFHALEQDASKEQQLRHKLGGGSGESILVSQLQHGLTLEFEHSDSPRRLRLVLSELLAIMNKVSECNGEFFFKSSELFESAVYLEEAADVLCILQAELPSLLPIVDVAEALLRVRNGAWFLCLLVANVPDSFNEVCRGLIKNGERQDEESLGGRRRTDALRFLCRMNPSQALKVRGMVVEECHLPGLGVALTLDHTKTEACEDGVSDLVCFVSGLLLGTNAKVRTWFGTFIRNGQQRKRETSGSVLWQMRRQLLLELMGILPTVRSTRIVEEADVEMEPTVSVYSGLKEEHVVKASALLRLYCALMGIAGLKPTEEEAEQLLQLMTSRPPATPAGVRFVSLSFCMLLAFSTLVSTPEQEQLMVLWLSWMIKEEAYFESTSGVSASFGEMLLLVAMYFHSNQLSAIIDLVCSTLGMKIVIKPSSLSRMKTIFTQEIFTEQVVTAHAVRVPVTSNLSANITGFLPIHCIYQLLRSRSFTKHKVSIKDWIYRQLCETSTPLHPQLLPLIDVYINSILTPASKSNPEATNQPVTEQEILNLFQEVIGGDSVRLTQRFSITAQLLVLYYILSYEEALLANTKTLASMQRKPKSYSSSLMDQIPIKFLIRQAQGLQQELGGLHSALLRLLATNYPHLCIVDDWICEEEITGTDALLRRMLLTSNAKTHSPKQLQEAFSAVPVSHTQVMQIMEHLTLLSASELIPYAEVLTSNMNQLLNSGVPRRILQTVNKLWMVLNTVMPRRLWVMTVNALQPSIKFIRQQKYTQNDLMIDPLIVLRCDRRVHRCPPLMDVTLHMLNGYLLASKAYLSAHLKETAEQDRPSPNNTVGLVGQTDAPEVTREELKNALLAAQDSAAVQILLEICLPTEEEKAKGANSDISLRNTQGVTTISTPSKETEEGEDNLLCNLREVQCLICCLLHQMYIADPNIAKLVHFQGYPCELLPLTVAGIPSMHICLDFIPELIAQPELEKQIFAIQLLSHLCIQYALPKSLSVARLAVNVMGTLLTVLTQAKRYSFFMPTLPSLVSFCRAFPPLYEDIMSLLIQIGQVCASDVATQTRDIDPIITRLQQIKEKPSGWSQICKDPSYKNGSRDTGSMDPDVQLCHCIESTIIEIINMSVSGI", "length": 1198 }, "evidence": [ { "id": "A0A8V1AC67", "url": "https://omabrowser.org/oma/group/A0A8V1AC67/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9H0H0-1", "protein_name": "Integrator complex subunit 2", "gene_name": "INTS2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTECTSLQFVSPFAFEAMQKVDVVCLASLSDPELRLLLPCLVRMALCAPADQSQSWAQDKKLILRLLSGVEAVNSIVALLSVDFHALEQDASKEQQLRHKLGGGSGESILVSQLQHGLTLEFEHSDSPRRLRLVLSELLAIMNKVSESNGEFFFKSSELFESPVYLEEAADVLCILQAELPSLLPIVDVAEALLHVRNGAWFLCLLVANVPDSFNEVCRGLIKNGERQDEESLGGRRRTDALRFLCKMNPSQALKVRGMVVEECHLPGLGVALTLDHTKNEACEDGVSDLVCFVSGLLLGTNAKVRTWFGTFIRNGQQRKRETSSSVLWQMRRQLLLELMGILPTVRSTRIVEEADVDMEPNVSVYSGLKEEHVVKASALLRLYCALMGIAGLKPTEEEAEQLLQLMTSRPPATPAGVRFVSLSFCMLLAFSTLVSTPEQEQLMVVWLSWMIKEEAYFESTSGVSASFGEMLLLVAMYFHSNQLSAIIDLVCSTLGMKIVIKPSSLSRMKTIFTQEIFTEQVVTAHAVRVPVTSNLSANITGFLPIHCIYQLLRSRSFTKHKVSIKDWIYRQLCETSTPLHPQLLPLIDVYINSILTPASKSNPEATNQPVTEQEILNIFQGVIGGDNIRLNQRFSITAQLLVLYYILSYEEALLANTKTLAAMQRKPKSYSSSLMDQIPIKFLIRQAQGLQQELGGLHSALLRLLATNYPHLCIVDDWICEEEITGTDALLRRMLLTNNAKNHSPKQLQEAFSAVPVNNTQVMQIIEHLTLLSASELIPYAEVLTSNMSQLLNSGVPRRILQTVNKLWMVLNTVMPRRLWVMTVNALQPSIKFVRQQKYTQNDLMIDPLIVLRCDQRVHRCPPLMDITLHMLNGYLLASKAYLSAHLKETEQDRPSQNNTIGLVGQTDAPEVTREELKNALLAAQDSAAVQILLEICLPTEEEKANGVNPDSLLRNVQSVITTSAPNKGMEEGEDNLLCNLREVQCLICCLLHQMYIADPNIAKLVHFQGYPCELLPLTVAGIPSMHICLDFIPELIAQPELEKQIFAIQLLSHLCIQYALPKSLSVARLAVNVMGTLLTVLTQAKRYAFFMPTLPSLVSFCRAFPPLYEDIMSLLIQIGQVCASDVATQTRDIDPIITRLQQIKEKPSGWSQICKDSSYKNGSRDTGSMDPDVQLCHCIERTVIEIINMSVSGI", "length": 1196 }, "evidence": [ { "id": "A0A8V1AC67", "url": "https://omabrowser.org/oma/group/A0A8V1AC67/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VX31-1", "protein_name": "Integrator complex subunit 2", "gene_name": "IntS2", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MPVRMYDVSPRVFCAMQNLDITLLASYPEAEIRPVLPSLVRMSLLSPLDNTESSMESRKEILAVLIGIEVVNSIVSYLQVNYHELENELKKELQARQKSAFFEGQQHEYGLQSGIALGFERADVARKVRVVLSEIFNLQQQVSEQKPAAHSEMLDDGIYLEEVVDILCIALAELPSLLNILELTDALVHVPNGHRIICALVANFPDCYRDVVSHVIANCDEDGSDGKHRLMLLMGLSEMNPSQALANRSMCVDMLKVPSFMLKLTLKHPEDLIAFLTGLLLGNDQNLRSWFAAYIRSSQKRKGDALNLVRVELLQKVIQTTTNAAELRDFNLQGAVLLRLYCALRGIGGLKFNDDEINALSQLVTSCPQATPSGVRFVTLALCMLIACPSLVSTIPLENKAVEWLQWLIREDAFFCKRPGTSTSLGEMLLLLAIHFHSNQISAISEMVCSTLAMKIPIRPNSTNRIKQLFTQDLFTEQVVALHAVRVPVTPNLNGTILCYLPVHCIQQLLKSRTFLKHKVPIKSWIFKQICSSVRPVHPVMPALVEVFVNTLIIPNPTGKVNIDHMHRPFTEAEILHVFRTSKLTFFAEELPPMAESQELNQIEVTCPLTAQLLMIYYLMLYEDTRLMNLSALGGRKQKEYSNNFLGGLPLKYLLQKAHHYHNDYLSLFHPLLRLIISNYPHLSMVDDWLEEHNLAQGNSTVVVSKHELKPETLDRALAAIQTKPHLAIRVFKQLLQMPPETQAQYGQQLVKHLPMVFAKSVPRYVKDLYNDIWLRLNAVLPTTLWIMSLRAITNGSDTMDRRTFANESLLEPMEVLSCPRFVFCSPYLLMILLRILKGSLAASKTYLNVHMQMQQKQVLDKNGMMQTDAIWEDLRTTLIASQESAAVHILLEVLDYIASKATDRVSHLELREIQGIIGTYVHQAFISEPSLAKLVHFQTYPKSVIPMMVASVPSMHICIDFVHEFLNVTEMEKQIFTIDLTSHLVLNYSIPKSLGVSKFCLNVIQTTLSMLTASTKCRFLRNVMPAMVRFVETFPILADDCVNILMTTGRILHSQSSLGMTTMEMPLTDSDKLCTYRDAQLHIIMIEDAFKALVTAVMKKSDLY", "length": 1105 }, "evidence": [ { "id": "A0A8V1AC67", "url": "https://omabrowser.org/oma/group/A0A8V1AC67/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "integrator complex", "id": "GO:0032039", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032039", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AC67", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC67" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "snRNA 3'-end processing", "id": "GO:0034472", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034472", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AC67", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC67" } ], "pmid": "" }, { "name": "snRNA processing", "id": "GO:0016180", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016180", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AC67", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC67" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1188, "end_pos": 1190, "annotation": "n_glycosylation_sequon" }, { "start_pos": 280, "end_pos": 282, "annotation": "n_glycosylation_sequon" }, { "start_pos": 323, "end_pos": 325, "annotation": "n_glycosylation_sequon" }, { "start_pos": 362, "end_pos": 364, "annotation": "n_glycosylation_sequon" }, { "start_pos": 539, "end_pos": 541, "annotation": "n_glycosylation_sequon" }, { "start_pos": 750, "end_pos": 752, "annotation": "n_glycosylation_sequon" }, { "start_pos": 766, "end_pos": 768, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 414 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1188, "end_pos": 1190 }, { "start_pos": 280, "end_pos": 282 }, { "start_pos": 323, "end_pos": 325 }, { "start_pos": 362, "end_pos": 364 }, { "start_pos": 539, "end_pos": 541 }, { "start_pos": 750, "end_pos": 752 }, { "start_pos": 766, "end_pos": 768 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": 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"publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AC88-1", "uniprot_ac": "A0A8V1AC88", "uniprot_id": "A0A8V1AC88_CHICK", "mass": { "chemical_mass": 99274.0, "monoisotopic_mass": 99274.0 }, "refseq": { "ac": "XP_004946787", "name": "BCAS3 microtubule associated cell migration factor isoform X4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004946787" }, "gene_names": [ { "name": "BCAS3", "type": "recommended", "evidence": [ { "id": "A0A8V1AC88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC88" } ] }, { "name": "BCAS3", "type": "synonym", "evidence": [ { "id": "XP_004946787", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004946787" } ] } ], "protein_names": [ { "name": "BCAS3 microtubule associated cell migration factor", "type": "recommended", "evidence": [ { "id": "A0A8V1AC88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC88/entry#names_and_taxonomy" } ] }, { "name": "BCAS3 microtubule associated cell migration factor isoform X4", "type": "synonym", "evidence": [ { "id": "XP_004946787", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004946787" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052550.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004946787", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004946787" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AC88", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC88" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "BCAS3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC88", "locus": { "chromosome": "19", "start_pos": 8132935, "end_pos": 8435658, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029324", "url": "https://www.ensembl.org/id/ENSGALG00010029324" } ] } } ], "crossref": [ { "id": "A0A8V1AC88", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AC88", "database": "AlphaFoldDB", "categories": [] }, { "id": "417643", "url": "https://www.ncbi.nlm.nih.gov/gene/417643", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022175", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022175", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045142", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045142", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048382", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048382", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AC88", "url": "https://www.orthodb.org/?gene=A0A8V1AC88", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AHI2", "url": "https://www.orthodb.org/?gene=A0A8V1AHI2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AHI9", "url": "https://www.orthodb.org/?gene=A0A8V1AHI9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AJJ8", "url": "https://www.orthodb.org/?gene=A0A8V1AJJ8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ALM2", "url": "https://www.orthodb.org/?gene=A0A8V1ALM2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AN67", "url": "https://www.orthodb.org/?gene=A0A8V1AN67", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13268", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13268", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13268:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13268:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12490", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12490", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21034", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21034", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004946787", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004946787", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AC88", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC88", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AC88-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC88-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHI2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHI2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHI2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHI2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHI9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHI9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHI9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHI9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJJ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJJ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJJ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJJ8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALM2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALM2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALM2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALM2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AN67", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN67", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AN67-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN67-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MATESPRRPSRCTGGVVVRPQAVTEQSYMESVVTFLQDVVPQAYSGTPPAEEKEKIIWVRFENADLNDTSRNMEFHEVHSTGNEPPLLLMIGYSDGMQVWSIPISGEAQELFSVRHGPVRAARILPAPQISAQKCDSFSEKRPLLGVCKSIGSSGTSPPYCCVDLYSLRTGEMVKSIQFKTPIYDLHCNKRILVVVLQEKIAAFDSCTFTKKFFVTSCYPCPGPNMNPIALGSRWLAYAENKLIRCHQSRGGACGDNIQSYTATVISAAKTIKTGLTMVGKVVTQLTGTLPSGATEEEILAHSNVRRSPLVPGVITIIDTETVAEGQVLVSEDSDSAGIVAHFPAHEKPICCMAFNPSGMLLVTTDTLGHDFHVFQILTHPWSSSQSAVHHLYTLHRGETEAKVQDISFSHDCRWVVVSTLRGTSHVFPINPYGGQPCVRTHMSPRVVNRMSRFQKSAGLEEIEQELTSKQGGRCSPVPGLSSSPSGSPLHGKLNSQDTYNNFTNNNPGNPRLLPLPSLTVVLPLAQIKQPMTLGTITKRTGKTKPAPQISPSKSVGGEFCVAAVFGSSRSWFANNAGLKREKDQSKQFVVESLYIISCYGSLVEHVLEPRPLSTAPKISDDTPLEMVTCPRASWTLVRTPQWNELQPPFNANHPLLLAADAVQYYQYLLAGLVPPGSPGPITRHESYDSLASDHSGQEDEEWLSQVEIVTHTGPHRRLWMGPQFQFKTIHPSGQTTVISSSSSVLQSHGPSDTPQPLLDFDTDDLDLNSLRIQPVRSEPVSMPGSSRPVSDRRGVSTVIDATSGAFDRSVTLLEVCGSWPENFGLRHMSSMEHTDEGLRERLADAMCESPSRDIVGSGTELQREGSIETLSNSSGSTSGSIPRNFDGYRSPLPTNENQPLSLFPTGFP", "length": 909, "header": "tr|A0A8V1AC88-1|A0A8V1AC88_CHICK Isoform 1 of BCAS3 microtubule associated cell migration factor OS=Gallus gallus OX=9031 GN=BCAS3 PE=1 SV=1 CANONICAL=A0A8V1AC88-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AC88-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC88/entry#A0A8V1AC88-1", "sequence": { "sequence": "MATESPRRPSRCTGGVVVRPQAVTEQSYMESVVTFLQDVVPQAYSGTPPAEEKEKIIWVRFENADLNDTSRNMEFHEVHSTGNEPPLLLMIGYSDGMQVWSIPISGEAQELFSVRHGPVRAARILPAPQISAQKCDSFSEKRPLLGVCKSIGSSGTSPPYCCVDLYSLRTGEMVKSIQFKTPIYDLHCNKRILVVVLQEKIAAFDSCTFTKKFFVTSCYPCPGPNMNPIALGSRWLAYAENKLIRCHQSRGGACGDNIQSYTATVISAAKTIKTGLTMVGKVVTQLTGTLPSGATEEEILAHSNVRRSPLVPGVITIIDTETVAEGQVLVSEDSDSAGIVAHFPAHEKPICCMAFNPSGMLLVTTDTLGHDFHVFQILTHPWSSSQSAVHHLYTLHRGETEAKVQDISFSHDCRWVVVSTLRGTSHVFPINPYGGQPCVRTHMSPRVVNRMSRFQKSAGLEEIEQELTSKQGGRCSPVPGLSSSPSGSPLHGKLNSQDTYNNFTNNNPGNPRLLPLPSLTVVLPLAQIKQPMTLGTITKRTGKTKPAPQISPSKSVGGEFCVAAVFGSSRSWFANNAGLKREKDQSKQFVVESLYIISCYGSLVEHVLEPRPLSTAPKISDDTPLEMVTCPRASWTLVRTPQWNELQPPFNANHPLLLAADAVQYYQYLLAGLVPPGSPGPITRHESYDSLASDHSGQEDEEWLSQVEIVTHTGPHRRLWMGPQFQFKTIHPSGQTTVISSSSSVLQSHGPSDTPQPLLDFDTDDLDLNSLRIQPVRSEPVSMPGSSRPVSDRRGVSTVIDATSGAFDRSVTLLEVCGSWPENFGLRHMSSMEHTDEGLRERLADAMCESPSRDIVGSGTELQREGSIETLSNSSGSTSGSIPRNFDGYRSPLPTNENQPLSLFPTGFP", "length": 909, "header": "tr|A0A8V1AC88-1|A0A8V1AC88_CHICK Isoform 1 of BCAS3 microtubule associated cell migration factor OS=Gallus gallus OX=9031 GN=BCAS3 PE=1 SV=1 CANONICAL=A0A8V1AC88-1" }, "locus": { "chromosome": "19", "start_pos": 8434552, "end_pos": 8134179, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070921.1", "url": "https://www.ensembl.org/id/ENSGALT00010070921.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043612.1", "url": "https://www.ensembl.org/id/ENSGALP00010043612.1" } ] } }, { "isoform_ac": "A0A8V1AHI2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC88/entry#A0A8V1AHI2-1", "sequence": { "sequence": "MATESPRRPSRCTGGVVVRPQAVTEQSYMESVVTFLQDVVPQFLLRTVKHAAWKHCKSPSEFLFVSHLLMGICGAQN", "length": 77, "header": "tr|A0A8V1AHI2-1|A0A8V1AC88_CHICK Computationally mapped isoform of BCAS3 microtubule associated cell migration factor OS=Gallus gallus OX=9031 GN=BCAS3 PE=1 SV=1 CANONICAL=A0A8V1AC88-1" }, "locus": { "chromosome": "19", "start_pos": 8434552, "end_pos": 8431500, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070918.1", "url": "https://www.ensembl.org/id/ENSGALT00010070918.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043609.1", "url": "https://www.ensembl.org/id/ENSGALP00010043609.1" } ] } }, { "isoform_ac": "A0A8V1AHI9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC88/entry#A0A8V1AHI9-1", "sequence": { "sequence": "MATESPRRPSRCTGGVVVRPQAVTEQSYMESVVTFLQDVVPQAYSGTPPAEEKEKIIWVRFENADLNDTSRNMEFHEVHSTGNEPPLLLMIGYSDGMQVWSIPISGEAQELFSVRHGPVRAARILPAPQISAQKCDSFSEKRPLLGVCKSIGSSGTSPPYCCVDLYSLRTGEMVKSIQFKTPIYDLHCNKRILVVVLQEKIAAFDSCTFTKKFFVTSCYPCPGPNMNPIALGSRWLAYAENKLIRCHQSRGGACGDNIQSYTATVISAAKTIKTGLTMVGKVVTQLTGTLPSGATEEEILAHSNVRRSPLVPGVITIIDTETVAEGQVLVSEDSDSAGIVAHFPAHEKPICCMAFNPSGMLLVTTDTLGHDFHVFQILTHPWSSSQSAVHHLYTLHRGETEAKVQDISFSHDCRWVVVSTLRGTSHVFPINPYGGQPCVRTHMSPRVVNRMSRFQKSAGLEEIEQELTSKQGGRCSPVPGLSSSPSGSPLHGKLNSQDTYNNFTNNNPGNPRLLPLPSLTVVLPLAQIKQPMTLGTITKRTGPYLFGAGCFSIKAPCKTKPAPQISPSKSVGGEFCVAAVFGSSRSWFANNAGLKREKDQSKQFVVESLYIISCYGSLVEHVLEPRPLSTAPKISDDTPLEMVTCPRASWTLVRTPQWNELQPPFNANHPLLLAADAVQYYQYLLAGLVPPGSPGPITRHESYDSLASDHSGQEDEEWLSQVEIVTHTGPHRRLWMGPQFQFKTIHPSGQTTVISSSSSVLQSHGPSDTPQPLLDFDTDDLDLNSLRIQPVRSEPVSMPGSSRPVSDRRGVSTVIDATSGKNTLVFLFSLILVAFINHIFSLPGNTFTNQCCALEGLSQFSAALTGKCCLTHMYLKGYNHVDFSSYHSYLKSQHCHETQMLYLH", "length": 904, "header": "tr|A0A8V1AHI9-1|A0A8V1AC88_CHICK Computationally mapped isoform of BCAS3 microtubule associated cell migration factor OS=Gallus gallus OX=9031 GN=BCAS3 PE=1 SV=1 CANONICAL=A0A8V1AC88-1" }, "locus": { "chromosome": "19", "start_pos": 8434552, "end_pos": 8296609, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070923.1", "url": "https://www.ensembl.org/id/ENSGALT00010070923.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043614.1", "url": "https://www.ensembl.org/id/ENSGALP00010043614.1" } ] } }, { "isoform_ac": "A0A8V1AJJ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC88/entry#A0A8V1AJJ8-1", "sequence": { "sequence": "MATESPRRPSRCTGGVVVRPQAVTEQSYMESVVTFLQDVVPQAYSGTPPAEEKEKIIWVRFENADLNDTSRNMEFHEVHSTGNEPPLLLMIGYSDGMQVWSIPISGEAQELFSVRHGPVRAARILPAPQISAQKCDSFSEKRPLLGVCKSIGSSGTSPPYCCVDLYSLRTGEMVKSIQFKTPIYDLHCNKRILVVVLQEKIAAFDSCTFTKKFFVTSCYPCPGPNMNPIALGSRWLAYAENKLIRCHQSRGGACGDNIQSYTATVISAAKTIKTGLTMVGKVVTQLTGTLPSGATEEEILAHSNVRRSPLVPGVITIIDTETVAEGQVLVSEDSDSAGIVAHFPAHEKPICCMAFNPSGMLLVTTDTLGHDFHVFQILTHPWSSSQSAVHHLYTLHRGETEAKVQDISFSHDCRWVVVSTLRGTSHVFPINPYGGQPCVRTHMSPRVVNRMSRFQKSAGLEEIEQELTSKQGGRCSPVPGLSSSPSGSPLHGKLNSQDTYNNFTNNNPGNPRLLPLPSLTVVLPLAQIKQPMTLGTITKRTGKTKPAPQISPSKSVGGEFCVAAVFGSSRSWFANNAGLKREKDQSKQFVVESLYIISCYGSLVEHVLEPRPLSTAPKISDDTPLEMVTCPRASWTLVRTPQWNELQPPFNANHPLLLAADAVQYYQYLLAGLVPPGSPGPITRHESYDSLASDHSGQEDEEWLSQVEIVTHTGPHRRLWMGPQFQFKTIHPSGQTTVISSSSSVLQSHGPSDTPQPLLDFDTDDLDLNSLRIQPVRSEPVSMPGSSRPVSDRRGVSTVIDATSGSVCKTGVRLAETCSLRQRVLALHVTKQMDILTSEKD", "length": 841, "header": "tr|A0A8V1AJJ8-1|A0A8V1AC88_CHICK Computationally mapped isoform of BCAS3 microtubule associated cell migration factor OS=Gallus gallus OX=9031 GN=BCAS3 PE=1 SV=1 CANONICAL=A0A8V1AC88-1" }, "locus": { "chromosome": "19", "start_pos": 8434552, "end_pos": 8232767, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070920.1", "url": "https://www.ensembl.org/id/ENSGALT00010070920.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043611.1", "url": "https://www.ensembl.org/id/ENSGALP00010043611.1" } ] } }, { "isoform_ac": "A0A8V1ALM2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC88/entry#A0A8V1ALM2-1", "sequence": { "sequence": "MATESPRRPSRCTGGVVVRPQAVTEQSYMESVVTFLQDVVPQAYSGTPPAEEKEKIIWVRFENADLNDTSRNMEFHEVHSTGNEPPLLLMIGYSDGMQVWSIPISGEAQELFSVRHGPVRAARILPAPQISAQKCDSFSEKRPLLGVCKSIGSSGTSPPYCCVDLYSLRTGEMVKSIQFKTPIYDLHCNKRILVVVLQEKIAAFDSCTFTKKFFVTSCYPCPGPNMNPIALGSRWLAYAENKLIRCHQSRGGACGDNIQSYTATVISAAKTIKTGLTMVGKVVTQLTGTLPSGATEEEILAHSNVRRSPLVPGVITIIDTETVAEGQVLVSEDSDSAGIVAHFPAHEKPICCMAFNPSGMLLVTTDTLGHDFHVFQILTHPWSSSQSAVHHLYTLHRGETEAKVQDISFSHDCRWVVVSTLRGTSHVFPINPYGGQPCVRTHMSPRVVNRMSRFQKSAGLEEIEQELTSKQGGRCSPVPGLSSSPSGSPLHGKLNSQDTYNNFTNNNPGNPRLLPLPSLTVVLPLAQIKQPMTLGTITKRTGKTKPAPQISPSKSVGGEFCVAAVFGSSRSWFANNAGLKREKDQSKQFVVESLYIISCYGSLVEHVLEPRPLSTAPKISDDTPLEMVTCPRASWTLVRTPQWNELQPPFNANHPLLLAADAVQYYQYLLAGLVPPGSPGPITRHESYDSLASDHSGQEDEEWLSQVEIVTHTGPHRRLWMGPQFQFKTIHPSGQTTVISSSSSVLQSHGPSDTPQPLLDFDTDDLDLNSLRIQPVRSEPVSMPGSSRPVSDRRGVSTVIDATSGAFDRSVTLLEVCGSWPENFGLRHMSSMEHTDEGLRERLADAMCESPSRDIVGSGTGTKKRCDQRSLTSHPMKQPVK", "length": 881, "header": "tr|A0A8V1ALM2-1|A0A8V1AC88_CHICK Computationally mapped isoform of BCAS3 microtubule associated cell migration factor OS=Gallus gallus OX=9031 GN=BCAS3 PE=1 SV=1 CANONICAL=A0A8V1AC88-1" }, "locus": { "chromosome": "19", "start_pos": 8434552, "end_pos": 8145567, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070919.1", "url": "https://www.ensembl.org/id/ENSGALT00010070919.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043610.1", "url": "https://www.ensembl.org/id/ENSGALP00010043610.1" } ] } }, { "isoform_ac": "A0A8V1AN67-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC88/entry#A0A8V1AN67-1", "sequence": { "sequence": "MATESPRRPSRCTGGVVVRPQAVTEQSYMESVVTFLQDVVPQAYSGTPPAEEKEKIIWVRFENADLNDTSRNMEFHEVHSTGNEPPLLLMIGYSDGMQVWSIPISGEAQELFSVRHGPVRAARILPAPQISAQKCDSFSEKRPLLGVCKSIGSSGTSPPYCCVDLYSLRTGEMVKSIQFKTPIYDLHCNKRILVVVLQEKIAAFDSCTFTKKFFVTSCYPCPGPNMNPIALGSRWLAYAENKLIRCHQSRGGACGDNIQSYTATVISAAKTIKTGLTMVGKVVTQLTGTLPSGATEEEILAHSNVRRSPLVPGVITIIDTETVAEGQVLVSEDSDSAGIVAHFPAHEKPICCMAFNPSGMLLVTTDTLGHDFHVFQILTHPWSSSQSAVHHLYTLHRGETEAKVQDISFSHDCRWVVVSTLRGTSHVFPINPYGGQPCVRTHMSPRVVNRMSRFQKSAGLEEIEQELTSKQGGRCSPVPGLSSSPSGSPLHGKLNSQDTYNNFTNNNPGNPRLLPLPSLTVVLPLAQIKQPMTLGTITKRTGKTKPAPQISPSKSVGGEFCVAAVFGSSRSWFANNAGLKREKDQSKQFVVESLYIISCYGSLVEHVLEPRPLSTAPKISDDTPLEMVTCPRASWTLVRTPQWNELQPPFNANHPLLLAADAVQYYQYLLAGLVPPGSPGPITRHESYDSLASDHSGQEDEEWLSQVEIVTHTGPHRRLWMGPQFQFKTIHPSGQTTVISSSSSVLQSHGPSDTPQPLLDFDTDDLDLNSLRIQPVRSEPVSMPGSSRPVSDRRGVSTVIDATSELQREGSIETLSNSSGSTSGSIPRNFDGYRSPLPTNENQPLSLFPTGFP", "length": 853, "header": "tr|A0A8V1AN67-1|A0A8V1AC88_CHICK Computationally mapped isoform of BCAS3 microtubule associated cell migration factor OS=Gallus gallus OX=9031 GN=BCAS3 PE=1 SV=1 CANONICAL=A0A8V1AC88-1" }, "locus": { "chromosome": "19", "start_pos": 8434552, "end_pos": 8134179, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070922.1", "url": "https://www.ensembl.org/id/ENSGALT00010070922.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043613.1", "url": "https://www.ensembl.org/id/ENSGALP00010043613.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "angiogenesis", "id": "GO:0001525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001525", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AC88", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC88" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AC88", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC88" } ], "pmid": "" }, { "name": "response to starvation", "id": "GO:0042594", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042594", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AC88", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC88" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AC88", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC88" } ], "pmid": "" }, { "name": "autophagy", "id": "GO:0006914", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006914", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AC88", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC88" } ], "pmid": "" }, { "name": "cellular response to estrogen stimulus", "id": "GO:0071391", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071391", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AC88", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC88" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 7, "go_terms": [ { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AC88", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC88" } ], "pmid": "" }, { "name": "histone binding", "id": "GO:0042393", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042393", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AC88", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC88" } ], "pmid": "" }, { "name": "beta-tubulin binding", "id": "GO:0048487", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048487", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AC88", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC88" } ], "pmid": "" }, { "name": "phosphatidylinositol binding", "id": "GO:0035091", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035091", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AC88", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC88" } ], "pmid": "" }, { "name": "nuclear receptor binding", "id": "GO:0016922", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016922", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AC88", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC88" } ], "pmid": "" }, { "name": "acetyltransferase activator activity", "id": "GO:0010698", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010698", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AC88", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC88" } ], "pmid": "" }, { "name": "histone acetyltransferase binding", "id": "GO:0035035", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035035", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AC88", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC88" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AC88", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC88" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AC88", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC88" } ], "pmid": "" }, { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AC88", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC88" } ], "pmid": "" }, { "name": "phagophore assembly site", "id": "GO:0000407", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000407", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AC88", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC88" } ], "pmid": "" }, { "name": "euchromatin", "id": "GO:0000791", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000791", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AC88", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC88" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 502, "end_pos": 504, "annotation": "n_glycosylation_sequon" }, { "start_pos": 67, "end_pos": 69, "annotation": "n_glycosylation_sequon" }, { "start_pos": 873, "end_pos": 875, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AC88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC88" }, { "id": "PF12490", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12490" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BCAS3", "eco_id": "ECO_0000259", "start_pos": 696, "end_pos": 738, "start_aa": "Ser", "end_aa": "Val", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1AC88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC88" }, { "id": "PF21034", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21034" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BCAS3 WD40", "eco_id": "ECO_0000259", "start_pos": 8, "end_pos": 460, "start_aa": "Arg", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 502, "end_pos": 504 }, { "start_pos": 67, "end_pos": 69 }, { "start_pos": 873, "end_pos": 875 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": 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"publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AC92-1", "uniprot_ac": "A0A8V1AC92", "uniprot_id": "A0A8V1AC92_CHICK", "mass": { "chemical_mass": 12500.0, "monoisotopic_mass": 12500.0 }, "refseq": { "ac": "XP_040508936", "name": "putative uncharacterized protein GUCA1ANB isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040508936" }, "gene_names": [ { "name": "GUCA1ANB", "type": "recommended", "evidence": [ { "id": "A0A8V1AC92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC92" } ] }, { "name": "GUCA1ANB", "type": "synonym", "evidence": [ { "id": "XP_040508936", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040508936" } ] } ], "protein_names": [ { "name": "Ciliary microtubule inner protein 3", "type": "synonym", "evidence": [ { "id": "A0A8V1AC92", "database": "UniProtKB", "url": 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This record is derived from a genomic sequence (NC_052557.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040508936", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040508936" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AC92", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC92" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "GUCA1ANB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC92", "locus": {} } ], "crossref": [ { "id": "A0A8V1AC92", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AC92", "database": "AlphaFoldDB", "categories": [] }, { "id": "121107626", "url": "https://www.ncbi.nlm.nih.gov/gene/121107626", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR054446", "url": 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"database": "UniProtKB", "id": "A0A8V1ACD5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACD5" } ], "pmid": "" }, { "name": "dendrite development", "id": "GO:0016358", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016358", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACD5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACD5" } ], "pmid": "" }, { "name": "heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules", "id": "GO:0007157", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007157", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACD5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACD5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "scavenger receptor activity", "id": "GO:0005044", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005044", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACD5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACD5" } ], "pmid": "" }, { "name": "low-density lipoprotein particle binding", "id": "GO:0030169", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030169", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACD5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACD5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACD5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACD5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1023, "end_pos": 1025, "annotation": "n_glycosylation_sequon" }, { "start_pos": 371, "end_pos": 373, "annotation": "n_glycosylation_sequon" }, { "start_pos": 463, "end_pos": 465, "annotation": "n_glycosylation_sequon" }, { "start_pos": 513, "end_pos": 515, "annotation": "n_glycosylation_sequon" }, { "start_pos": 556, "end_pos": 558, "annotation": "n_glycosylation_sequon" }, { "start_pos": 567, "end_pos": 569, "annotation": "n_glycosylation_sequon" }, { "start_pos": 648, "end_pos": 650, "annotation": "n_glycosylation_sequon" }, { "start_pos": 659, "end_pos": 661, "annotation": "n_glycosylation_sequon" }, { "start_pos": 873, "end_pos": 875, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1ACD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACD5" }, { "id": "PS50026", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50026" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EGF-like", "eco_id": "ECO_0000259", "start_pos": 227, "end_pos": 261, "start_aa": "Thr", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 835 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1023, "end_pos": 1025 }, { "start_pos": 371, "end_pos": 373 }, { "start_pos": 463, "end_pos": 465 }, { "start_pos": 513, "end_pos": 515 }, { "start_pos": 556, "end_pos": 558 }, { "start_pos": 567, "end_pos": 569 }, { "start_pos": 648, "end_pos": 650 }, { "start_pos": 659, "end_pos": 661 }, { "start_pos": 873, "end_pos": 875 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": 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"publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1ACF0-1", "uniprot_ac": "A0A8V1ACF0", "uniprot_id": "A0A8V1ACF0_CHICK", "mass": { "chemical_mass": 69963.0, "monoisotopic_mass": 69963.0 }, "refseq": {}, "gene_names": [ { "name": "AATF", "type": "recommended", "evidence": [ { "id": "A0A8V1ACF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF0" } ] } ], "protein_names": [ { "name": "Apoptosis antagonizing transcription factor", "type": "synonym", "evidence": [ { "id": "A0A8V1ACF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF0/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACF0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "AATF", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF0", "locus": { "chromosome": "19", "start_pos": 8926515, "end_pos": 8884570, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029352", "url": "https://www.ensembl.org/id/ENSGALG00010029352" } ] } } ], "crossref": [ { "id": "A0A8V1ACF0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1ACF0", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR012617", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012617", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025160", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025160", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039223", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039223", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ACF0", "url": "https://www.orthodb.org/?gene=A0A8V1ACF0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ACF5", "url": "https://www.orthodb.org/?gene=A0A8V1ACF5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AHQ2", "url": "https://www.orthodb.org/?gene=A0A8V1AHQ2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AHQ8", "url": "https://www.orthodb.org/?gene=A0A8V1AHQ8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AJQ9", "url": "https://www.orthodb.org/?gene=A0A8V1AJQ9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ALS6", "url": "https://www.orthodb.org/?gene=A0A8V1ALS6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ANC0", "url": "https://www.orthodb.org/?gene=A0A8V1ANC0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15565", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15565", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15565:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15565:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08164", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08164", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13339", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13339", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1ACF0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ACF0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ACF5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ACF5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHQ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHQ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHQ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHQ2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHQ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHQ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHQ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHQ8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJQ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJQ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJQ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJQ9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALS6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALS6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALS6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALS6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ANC0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANC0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ANC0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANC0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAPLAQQLEELLNPRPDLRDPEDDAEEATVAKVIDRFEDETADDVLPVGNIRKKASVSLLEADQRYSGKATSRKALQEELWGDALSEEGSAEEALDEWYSGSEDSEDNGSSGSKTEEQPSSAGSDQEDNLEDDEERDSSAKAPKFSFQNITDFEKFAEGMDDVGSSDGEDEDDASIEEGSDDEKYEGENHDHVKDTNDNEDDGGVMTFSKGQTSDEVEKGKAVKNQLALWDQILEGRIKMQKALVIVNRLPQPDTFPLFRKEGGQEFDSAVESCCKAVDTLLRVLVDIQDELLYQCPGTRHLVDGKQSKPESDDEIPSSSDEERAGEAQEKRKRPPKRKLKAEDIPEFIAKRYSDYRTYRNHILQKWHEKTKLASGKMAKGFGAFERSILTQIDHILMDKERLLRRTQTKRSVYRVLGKEEQDSHPVPEHLPENSEVLPQADSNRHLKDIDEEIFDDDDFYHQLLRELIERKTTSLDPNDQVAMGRQWLAIQKLRSKIKKKVDRKASKGRKIRYHVHSKLVSFMAPIDHCTMNDDARWWASCGRELVSSSQRLDVGGSSNAFPLGCGTRLCFVRENCRLSLWEMEAEYLLLFGCCLVGYLTDFWMRAVQNAGTKAF", "length": 617, "header": "tr|A0A8V1ACF0-1|A0A8V1ACF0_CHICK Isoform 1 of Apoptosis antagonizing transcription factor OS=Gallus gallus OX=9031 GN=AATF PE=3 SV=1 CANONICAL=A0A8V1ACF0-1" }, "isoforms": [ { "isoform_ac": "A0A8V1ACF0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF0/entry#A0A8V1ACF0-1", "sequence": { "sequence": "MAAPLAQQLEELLNPRPDLRDPEDDAEEATVAKVIDRFEDETADDVLPVGNIRKKASVSLLEADQRYSGKATSRKALQEELWGDALSEEGSAEEALDEWYSGSEDSEDNGSSGSKTEEQPSSAGSDQEDNLEDDEERDSSAKAPKFSFQNITDFEKFAEGMDDVGSSDGEDEDDASIEEGSDDEKYEGENHDHVKDTNDNEDDGGVMTFSKGQTSDEVEKGKAVKNQLALWDQILEGRIKMQKALVIVNRLPQPDTFPLFRKEGGQEFDSAVESCCKAVDTLLRVLVDIQDELLYQCPGTRHLVDGKQSKPESDDEIPSSSDEERAGEAQEKRKRPPKRKLKAEDIPEFIAKRYSDYRTYRNHILQKWHEKTKLASGKMAKGFGAFERSILTQIDHILMDKERLLRRTQTKRSVYRVLGKEEQDSHPVPEHLPENSEVLPQADSNRHLKDIDEEIFDDDDFYHQLLRELIERKTTSLDPNDQVAMGRQWLAIQKLRSKIKKKVDRKASKGRKIRYHVHSKLVSFMAPIDHCTMNDDARWWASCGRELVSSSQRLDVGGSSNAFPLGCGTRLCFVRENCRLSLWEMEAEYLLLFGCCLVGYLTDFWMRAVQNAGTKAF", "length": 617, "header": "tr|A0A8V1ACF0-1|A0A8V1ACF0_CHICK Isoform 1 of Apoptosis antagonizing transcription factor OS=Gallus gallus OX=9031 GN=AATF PE=3 SV=1 CANONICAL=A0A8V1ACF0-1" }, "locus": { "chromosome": "19", "start_pos": 8916361, "end_pos": 8884606, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070983.1", "url": "https://www.ensembl.org/id/ENSGALT00010070983.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043674.1", "url": "https://www.ensembl.org/id/ENSGALP00010043674.1" } ] } }, { "isoform_ac": "A0A8V1ACF5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF0/entry#A0A8V1ACF5-1", "sequence": { "sequence": "MAAPLAQQLEELLNPRPDLRDPEDDAEEATVAKVIDRFEDETADDVLPVGNIRKKASVSLLEADQRYSGKATSRKALQEELWGDALSEEGSAEEALDEWYSGSEDSEDNGSSGSKTEEQPSSAGSDQEDNLEDDEERDSSAKAPKFSFQNITDFEKFAEGMDDVGSSDGEDEDDASIEEGSDDEKYEGENHDHVKDTNDNEDDGGVMTFSKGQTSDEVEKGKAVKNQLALWDQILEGRIKMQKALVIVNRLPQPDTFPLFRKEGGQEFDSAVESWLTTTEEGSPARDPSFVEYFYKRRSSETGCKAVDTLLRVLVDIQDELLYQCPGTRHLVDGKQSKPESDDEIPSSSDEERAGEAQEKRKRPPKRKLKAEDIPEFIAKRYSDYRTYRNHILQKWHEKTKLASGKMAKGFGAFERSILTQIDHILMDKERLLRRTQTKRSVYRVLGKEEQDSHPVPEHLPENSEVLPQADSNRHLKDIDEEIFDDDDFYHQLLRELIERKTTSLDPNDQVAMGRQWLAIQKLRSKIKKKVDRKASKGRKIRYHVHSKLVSFMAPIDHCTMNDDARTELYRSLFGRMMQSEGPERGWHPGPPAPAGSAPYTL", "length": 602, "header": "tr|A0A8V1ACF5-1|A0A8V1ACF5_CHICK Computationally mapped isoform of Apoptosis antagonizing transcription factor OS=Gallus gallus OX=9031 GN=AATF PE=3 SV=1 CANONICAL=A0A8V1ACF0-1" }, "locus": { "chromosome": "19", "start_pos": 8925270, "end_pos": 8884606, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070988.1", "url": "https://www.ensembl.org/id/ENSGALT00010070988.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043679.1", "url": "https://www.ensembl.org/id/ENSGALP00010043679.1" } ] } }, { "isoform_ac": "A0A8V1AHQ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF0/entry#A0A8V1AHQ2-1", "sequence": { "sequence": "MAAPLAQQLEELLNPRPDLRDPEDDAEEATVAKVIDRFEDETADDVLPVGNIRKKASVSLLEADQRYSGKATSRKALQEELWGDALSEEGSAEEALDEWYSGSEDSEDNGSSGSKTEEQPSSAGSDQEDNLEDDEERDSSAKAPKFSFQNITDFEKFAEGMDDVGSSDGEDEDDASIEEGSDDEKYEGENHDHVKDTNDNEDDGGVMTFSKGQTSDEVEKGKAVKNQLALWDQILEGRIKMQKALVIVNRLPQPDTFPLFRKEGGQEFDSAVESCCKAVDTLLRVLVDIQDELLYQCPGTRHLVDGKQSKPESDDEIPSSSDEERAGEAQEKRKRPPKRKLKAEDIPEFIAKRYSDYRTYRNHILQKWHEKTKLASGKMAKGFGAFERSILTQIDHILMDKERLLRRTQTKRSVYRVLGKEEQDSHPVPEHLPENSEVLPQADSNRHLKDIDEEIFDDDDFYHQLLRELIERKTTSLDPNDQVAMGRQWLAIQKLRSKIKKKVDRKASKGRKIRYHVHSKLVSFMAPIDHCTMNDDASPLHSLVFHKLHSKRILQARILQMHANGSAPNSW", "length": 571, "header": "tr|A0A8V1AHQ2-1|A0A8V1ACF0_CHICK Computationally mapped isoform of Apoptosis antagonizing transcription factor OS=Gallus gallus OX=9031 GN=AATF PE=3 SV=1 CANONICAL=A0A8V1ACF0-1" }, "locus": { "chromosome": "19", "start_pos": 8916725, "end_pos": 8884606, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070985.1", "url": "https://www.ensembl.org/id/ENSGALT00010070985.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043676.1", "url": "https://www.ensembl.org/id/ENSGALP00010043676.1" } ] } }, { "isoform_ac": "A0A8V1AHQ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF0/entry#A0A8V1AHQ8-1", "sequence": { "sequence": "MAAPLAQQLEELLNPRPDLRDPEDDAEEATVAKVIDRFEDETADDVLPVGNIRKKASVSLLEADQRYSGKATSRKALQEELWGDALSEEGSAEEALDEWYSGSEDSEDNGSSGSKTEEQPSSAGSDQEDNLEDDEERDSSAKAPKFSFQNITDFEKFAEGMDDVGSSDGEDEDDASIEEGSDDEKYEGENHDHVKDTNDNEDDGGVMTFSKGQTSDEVEKGKAVKNQLALWDQILEGRIKMQKALVIVNRLPQPDTFPLFRKEGGQEFDSAVESCCKAVDTLLRVLVDIQDELLYQCPGTRHLVDGKQSKPESDDEIPSSSDEERAGEAQEKRKRPPKRKLKAEDIPEFIAKRYSDYRTYRNHILQKWHEKTKLASGKMAKGFGAFERSILTQIDHILMDKERLLRRTQTKRSVYRVLGKEEQDSHPVPEHLPENSEVLPQADSNRHLKDIDEEIFDDDDFYHQLLRELIERKTTSLDPNDQVAMGRQWLAIQKLRSKIKKKVDRKASKGRKIRYHVHSKLVSFMAPIDHCTMNDDARTELYRSLFGRMMQSEGPERGWHPGPPAPAALSLLSSYLLPVNSFLARHAMY", "length": 589, "header": "tr|A0A8V1AHQ8-1|A0A8V1ACF0_CHICK Computationally mapped isoform of Apoptosis antagonizing transcription factor OS=Gallus gallus OX=9031 GN=AATF PE=3 SV=1 CANONICAL=A0A8V1ACF0-1" }, "locus": { "chromosome": "19", "start_pos": 8926368, "end_pos": 8884606, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070990.1", "url": "https://www.ensembl.org/id/ENSGALT00010070990.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043681.1", "url": "https://www.ensembl.org/id/ENSGALP00010043681.1" } ] } }, { "isoform_ac": "A0A8V1AJQ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF0/entry#A0A8V1AJQ9-1", "sequence": { "sequence": "MAAPLAQQLEELLNPRPDLRDPEDDAEEATVAKVIDRFEDETADDVLPVGNIRKKASVSLLEADQRYSGKATSRKALQEELWGDALSEEGSAEEALDEWYSGSEDSEDNGSSGSKTEEQPSSAGSDQEDNLEDDEERDSSAKAPKFSFQNITDFEKFAEGMDDVGSSDGEDEDDASIEEGSDDEKYEGENHDHVKDTNDNEDDGGVMTFSKGQTSDEVEKGKAVKNQLALWDQILEGRIKMQKALVIVNRLPQPDTFPLFRKEGGQEFDSAVESCCKAVDTLLRVLVDIQDELLYQCPGTRHLVDGKQSKPESDDEIPSSSDEERAGEAQEKRKRPPKRKLKAEDIPEFIAKRYSDYRTYRNHILQKWHEKTKLASGKMAKGFGAFERSILTQIDHILMDKERLLRRTQTKRSVYRVLGKEEQDSHPVPEHLPENSEVLPQADSNRHLKDIDEEIFDDDDFYHQLLRELIERKTTSLDPNDQVAMGRQWLAIQKLRSKIKKKVDRKASKGRKIRYHVHSKLVSFMAPIDHCTMNDDASMYNRAAHLLYFVPWERRHRRGQTEPGDSR", "length": 567, "header": "tr|A0A8V1AJQ9-1|A0A8V1ACF0_CHICK Computationally mapped isoform of Apoptosis antagonizing transcription factor OS=Gallus gallus OX=9031 GN=AATF PE=3 SV=1 CANONICAL=A0A8V1ACF0-1" }, "locus": { "chromosome": "19", "start_pos": 8919026, "end_pos": 8884606, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070987.1", "url": 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"database": "Ensembl Peptide", "id": "ENSGALP00010043680.1", "url": "https://www.ensembl.org/id/ENSGALP00010043680.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACF0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF0" } ], "pmid": "" }, { "name": "leucine zipper domain binding", "id": "GO:0043522", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043522", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACF0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleolus", "id": "GO:0005730", "url": 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Specifically acts as a glutamate mono-ADP-ribosylhydrolase by mediating the removal of mono-ADP-ribose attached to glutamate residues on proteins. Does not act on poly-ADP-ribosylated proteins: the poly-ADP-ribose chain of poly-ADP-ribosylated glutamate residues must by hydrolyzed into mono-ADP-ribosylated glutamate by PARG to become a substrate for OARD1. Deacetylates O-acetyl-ADP ribose, a signaling molecule generated by the deacetylation of acetylated lysine residues in histones and other proteins. Catalyzes the deacylation of O-acetyl-ADP-ribose, O-propionyl-ADP-ribose and O-butyryl-ADP-ribose, yielding ADP-ribose plus acetate, propionate and butyrate, respectively.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACI6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACI6#function" }, { "database": "UniProtKB", "id": "ARBA00058495", "url": "https://www.uniprot.org/uniprotkb/ARBA00058495#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACI6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACI6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "OARD1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACI6", "locus": { "chromosome": "26", "start_pos": 4758699, "end_pos": 4763029, "strand": "+", "evidence": [ { "database": 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"sequence": { "sequence": "GTERRPAGPAALRVTSPREKAPIGRRSLAPHVASCDWPPARRGHGGAAARCAAVPLRGGLGGRRGARGARAARPRGAGPAVWHVRVALRRGAGSVRVVSQENTARPQSAGDFEDILTTVYFLLEKNPHAQFWTTYQVRSADWSIEALLYKWKLKSIHIPLHSFSADKEHLASSSLPSRHTIEMMIISLARSDGT", "length": 194, "header": "tr|A0A8V1AHV8-1|A0A8V1ACK3_CHICK Computationally mapped isoform of Histone-arginine methyltransferase METTL23 OS=Gallus gallus OX=9031 GN=METTL23 PE=3 SV=1 CANONICAL=A0A8V1ACK3-1" }, "locus": { "chromosome": "18", "start_pos": 4872942, "end_pos": 4871056, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071036.1", "url": "https://www.ensembl.org/id/ENSGALT00010071036.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043727.1", "url": "https://www.ensembl.org/id/ENSGALP00010043727.1" } ] } }, { "isoform_ac": "A0A8V1ANF6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK3/entry#A0A8V1ANF6-1", "sequence": { "sequence": "MGEPRRAVRRYRFVGDSAGGEERAVLVLRVPEIGAGVSLPGIVAAKCGAQVTLSDSEELPQCLEISQQSCLLNHLPHVPVVGITWGRISPELLSLAPIDIILGSDVFFDPKDFEDILTTVYFLLEKNPHAQFWTTYQVRSADWSIEALLYKWKLKSIHIPLHSFSADKEHLASSSLPSRHTIEMMIISLARSDGT", "length": 195, "header": "tr|A0A8V1ANF6-1|A0A8V1ACK3_CHICK Computationally mapped isoform of Histone-arginine methyltransferase METTL23 OS=Gallus gallus OX=9031 GN=METTL23 PE=3 SV=1 CANONICAL=A0A8V1ACK3-1" }, "locus": { "chromosome": "18", "start_pos": 4872812, "end_pos": 4871056, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071035.1", "url": "https://www.ensembl.org/id/ENSGALT00010071035.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043726.1", "url": "https://www.ensembl.org/id/ENSGALP00010043726.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACK3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK3" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACK3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK3" } ], "pmid": "" }, { "name": "female pronucleus", "id": "GO:0001939", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001939", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACK3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK3" } ], "pmid": "" }, { "name": "male pronucleus", "id": "GO:0001940", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001940", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACK3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK3" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": 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"name": "epigenetic regulation of gene expression", "id": "GO:0040029", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0040029", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACK3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK3" } ], "pmid": "" }, { "name": "epigenetic programming in the zygotic pronuclei", "id": "GO:0044725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044725", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACK3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "heat shock protein binding", "id": "GO:0031072", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031072", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACK3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK3" } ], "pmid": "" }, { "name": "protein-arginine omega-N asymmetric methyltransferase activity", "id": "GO:0035242", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035242", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACK3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK3" } ], "pmid": "" }, { "name": "histone H3R17 methyltransferase activity", "id": "GO:0035642", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035642", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACK3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK3" } ], "pmid": "" }, { "name": "DNA-binding transcription factor binding", "id": "GO:0140297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140297", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACK3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK3" } ], "pmid": "" }, { "name": "methyltransferase activity", "id": "GO:0008168", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008168", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACK3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], 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"total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1ACK4-1", "uniprot_ac": "A0A8V1ACK4", "uniprot_id": "A0A8V1ACK4_CHICK", "mass": { "chemical_mass": 166672.0, "monoisotopic_mass": 166672.0 }, "refseq": { "ac": "XP_046757914", "name": "snRNA-activating protein complex subunit 4 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046757914" }, "gene_names": [ { "name": "SNAPC4", "type": "recommended", "evidence": [ { "id": "A0A8V1ACK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK4" } ] }, { "name": "SNAPC4", "type": "synonym", "evidence": [ { "id": "XP_046757914", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046757914" } ] } ], "protein_names": [ { "name": "snRNA-activating protein complex subunit 4", "type": "recommended", "evidence": [ { "id": "A0A8V1ACK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK4/entry#names_and_taxonomy" } ] }, { "name": "snRNA-activating protein complex 190 kDa subunit", "type": "synonym", "evidence": [ { "id": "A0A8V1ACK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK4/entry#names_and_taxonomy" } ] }, { "name": "snRNA-activating protein complex subunit 4 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_046757914", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046757914" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052548.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_046757914", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046757914" } ] }, { "annotation": "Part of the SNAPc complex required for the transcription of both RNA polymerase II and III small-nuclear RNA genes. Binds to the proximal sequence element (PSE), a non-TATA-box basal promoter element common to these 2 types of genes. Recruits TBP and BRF2 to the U6 snRNA TATA box.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACK4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK4#function" }, { "database": "UniProtKB", "id": "ARBA00025193", "url": "https://www.uniprot.org/uniprotkb/ARBA00025193#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACK4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SNAPC4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK4", "locus": { "chromosome": "17", "start_pos": 8514927, "end_pos": 8499315, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028149", "url": "https://www.ensembl.org/id/ENSGALG00010028149" } ] } } ], "crossref": [ { 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"Protein Classification" ] }, { "id": "MAFHQTK", "url": "https://omabrowser.org/oma/group/MAFHQTK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ACK4", "url": "https://www.orthodb.org/?gene=A0A8V1ACK4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46621", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46621", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46621:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46621:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00249", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00249", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13921", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13921", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-6807505", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6807505", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-76071", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-76071", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_046757914", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046757914", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1ACK4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ACK4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSRRDGPAGANLNAEREKIRREIEELERSLQLDVTSVDVAVSDSSLSSDDAEGDSSDAHAEMEVEREEDSSDDDLESSLLEDPETCLQMNYVYQEVIQEKIEEVELLIAQNKEQQKEILCELDGRKTTRTGDGRNLPSNIFLGHFMKPYFKDKTTGIGPPSNEDAKEKAAQGIKSFEQLLSTKWKSKEKVLLQKSVVSDRLQRLLQPKLLKLSYSNQKLENVKTEMEKQILEKQIKEVEREIEAINQLPESDLLGGRFDEHDWEKIANVHFDGRRSSEELKKFWQNWEHPNINKNEWTEEETERLKDIAAKRGYLDWQTVAQELGTNRTAFQCLQKYQAYNKDLKRKEWTRDEDKMLLELVQEMRVGSHIPYKKIAYYMEGRDSAQLIYRWTKSVDPSLKKGPWTPEEDAMLLAAVEKYGERDWYKIRAEVPGRSDAQCSDRYLKALHRDVKKGKWSLKEEEQLIDLVQKHGLGHWSKIASELPHRTRSQCLSKWKIMIGSKKRSRSAKRQHAEESSSCSESSSEDVELDLSDTSEEEKMNKEECTFPSIDLWIPTQTDVLESCQGRHQASSPFSFGSANARTSSSKIPNARREGGEEGANAKATELSTILRGMARPHSTDITVKNPKEEINKASRCGKQVLRVTLEDVRRVLRENTCFQRKRQSKLIMSSAATLTKTSGVGASAAEKHRGLWSTMGKSRRQERARWRKMNLDRKLLMAVTPWVGDVLLPCTLRAGKMAFDQTKAYSIQQKLKSVSLSSTPLFTLFIQLFRIDTNGCMKIIRERRADAARPQQASQNLESSSGNASQPPSNTQRALPALPSPPAPLAQAHRQKPKTVSELLREKRQMEKQLKEKAMQTKVFVAPQMMLSGPLIIQHPPQQMIPSAQVGSKPGAGGSTDSQVQCVSASPSAFTSVAGSASTPVVLESHSPSVPKVGELPGSSQETKVQSNKELNEQGPQNTPERGLFPSLNPAAAGKAPDRGGCNAQVLAGTSAPVVFQNQAFVPRRVTVVPFGIDSGNSKLSLPAPITYELTHSGPVNLLPALLAPQPGSHLTPDSMLPLTWVVTQQALLSSAVQAVVGVPQGLQAIVRSQSQASVTSSGSVSGLGAPPVSSGVNMPHPSHAETKTNPQLAAGSPAGKTAGVSHSASVFPVSSADPVCSVSGVSSATSAHSDSSSKTVDSSAAHNALPGGAPTLHAQLLPQMQLPASTEGSDSRCVTDVVSLGEKQDSSTTNGSSSNSDVLHKGDELQPRASIPHNSVAGNSEGSADQGLKYRPIASKPPPEQTESAPPQPTTSSAEKTLLDYSLISLEDDELVKEWLSGKQGVQVPPLQTRLPYFPPFLCNLKTLSKLLLQKAALEKQAARFLSPDGSQTEGEVDLNAITKLVHEKLGDDPAFLLLKARFLAAFTLPAVLATLPPPKVATTLSASKREYGESDEEEWQSEEEASEDESCGDELDAPSDETGGDEPGDRDADFPSKGMETEDSAAQSIVGTCTDGTASVPQIRRSVRIRKRFTKRRRV", "length": 1518, "header": "tr|A0A8V1ACK4-1|A0A8V1ACK4_CHICK Isoform 1 of snRNA-activating protein complex subunit 4 OS=Gallus gallus OX=9031 GN=SNAPC4 PE=4 SV=1 CANONICAL=A0A8V1ACK4-1" }, "isoforms": [ { "isoform_ac": "A0A8V1ACK4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK4/entry#A0A8V1ACK4-1", "sequence": { "sequence": "MSRRDGPAGANLNAEREKIRREIEELERSLQLDVTSVDVAVSDSSLSSDDAEGDSSDAHAEMEVEREEDSSDDDLESSLLEDPETCLQMNYVYQEVIQEKIEEVELLIAQNKEQQKEILCELDGRKTTRTGDGRNLPSNIFLGHFMKPYFKDKTTGIGPPSNEDAKEKAAQGIKSFEQLLSTKWKSKEKVLLQKSVVSDRLQRLLQPKLLKLSYSNQKLENVKTEMEKQILEKQIKEVEREIEAINQLPESDLLGGRFDEHDWEKIANVHFDGRRSSEELKKFWQNWEHPNINKNEWTEEETERLKDIAAKRGYLDWQTVAQELGTNRTAFQCLQKYQAYNKDLKRKEWTRDEDKMLLELVQEMRVGSHIPYKKIAYYMEGRDSAQLIYRWTKSVDPSLKKGPWTPEEDAMLLAAVEKYGERDWYKIRAEVPGRSDAQCSDRYLKALHRDVKKGKWSLKEEEQLIDLVQKHGLGHWSKIASELPHRTRSQCLSKWKIMIGSKKRSRSAKRQHAEESSSCSESSSEDVELDLSDTSEEEKMNKEECTFPSIDLWIPTQTDVLESCQGRHQASSPFSFGSANARTSSSKIPNARREGGEEGANAKATELSTILRGMARPHSTDITVKNPKEEINKASRCGKQVLRVTLEDVRRVLRENTCFQRKRQSKLIMSSAATLTKTSGVGASAAEKHRGLWSTMGKSRRQERARWRKMNLDRKLLMAVTPWVGDVLLPCTLRAGKMAFDQTKAYSIQQKLKSVSLSSTPLFTLFIQLFRIDTNGCMKIIRERRADAARPQQASQNLESSSGNASQPPSNTQRALPALPSPPAPLAQAHRQKPKTVSELLREKRQMEKQLKEKAMQTKVFVAPQMMLSGPLIIQHPPQQMIPSAQVGSKPGAGGSTDSQVQCVSASPSAFTSVAGSASTPVVLESHSPSVPKVGELPGSSQETKVQSNKELNEQGPQNTPERGLFPSLNPAAAGKAPDRGGCNAQVLAGTSAPVVFQNQAFVPRRVTVVPFGIDSGNSKLSLPAPITYELTHSGPVNLLPALLAPQPGSHLTPDSMLPLTWVVTQQALLSSAVQAVVGVPQGLQAIVRSQSQASVTSSGSVSGLGAPPVSSGVNMPHPSHAETKTNPQLAAGSPAGKTAGVSHSASVFPVSSADPVCSVSGVSSATSAHSDSSSKTVDSSAAHNALPGGAPTLHAQLLPQMQLPASTEGSDSRCVTDVVSLGEKQDSSTTNGSSSNSDVLHKGDELQPRASIPHNSVAGNSEGSADQGLKYRPIASKPPPEQTESAPPQPTTSSAEKTLLDYSLISLEDDELVKEWLSGKQGVQVPPLQTRLPYFPPFLCNLKTLSKLLLQKAALEKQAARFLSPDGSQTEGEVDLNAITKLVHEKLGDDPAFLLLKARFLAAFTLPAVLATLPPPKVATTLSASKREYGESDEEEWQSEEEASEDESCGDELDAPSDETGGDEPGDRDADFPSKGMETEDSAAQSIVGTCTDGTASVPQIRRSVRIRKRFTKRRRV", "length": 1518, "header": "tr|A0A8V1ACK4-1|A0A8V1ACK4_CHICK Isoform 1 of snRNA-activating protein complex subunit 4 OS=Gallus gallus OX=9031 GN=SNAPC4 PE=4 SV=1 CANONICAL=A0A8V1ACK4-1" }, "locus": { "chromosome": "17", "start_pos": 8513821, "end_pos": 8499346, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068208.1", "url": "https://www.ensembl.org/id/ENSGALT00010068208.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041951.1", "url": "https://www.ensembl.org/id/ENSGALP00010041951.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1292, "start_aa": "Thr", "end_pos": 1292, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1292", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-GGA-6807505", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6807505", "resource": "Reactome", "description": "RNA polymerase II transcribes snRNA genes" }, { "id": "R-GGA-76071", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-76071", "resource": "Reactome", "description": "RNA Polymerase III Transcription Initiation From Type 3 Promoter" } ], "orthologs": [ { "uniprot_canonical_ac": "E1BCK9-1", "protein_name": "snRNA-activating protein complex subunit 4", "gene_name": "SNAPC4", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MDVDAERERISREIQQLERILDPCCSSVSMDVSESSLNSDSDADLLPDEDLDSDAAGPLLSEEERWGEASNDEDDPKEKALPEDPETCLQLNMVYQEVVREKLAEVSLLLAQNREQQEEVMGDLVGVKGPKVKDDRNPPPNLYLGHFMKPYFRDRVTGVGPPANEDTREKAAQGIKAFTELLVTKWKTWEKVLLRKSVVSDRLQRLLQPKLLKLEYLQQKQSRATSELEKQILEKQAREAEKEVQDINQLPEEALLGDRLDSHDWDKISNVNFEGGRSTEEIRKFWQNHEHPSINKQEWSEQEVAQLKAVAAKHGHLDWQSIAEELGTHRSAFQCLQRYQQHNPALKRREWTEEEDRMLTRLVQAMRVGSHIPYRRIVYYMEGRDSMQLIYRWTKSLDPSLRKGLWAPEEDAKLLQAVAKYGEQDWFKIREEVPGRSDAQCRDRYLRRLHFSLKKGRWNSKEVKKLIELIEKYGVGHWAKIASELPHRSGSQCLSKWKIMVRQRQRARRRARWSPSSGSSSNSSWEDSEPEEAPKDVPEEAPAGGPEPPPAQYAVPDMDLWVPARQSTEELRGAVAGGCPRPPEGPDTAQATAPAPTGQLASRSRSADPRTVGCLCPATAHRWSSKGLLGKERLRQPHPPGSAPGLSPGGGSRDEARPRVQPQWARTAQRRQGHALQRRLLEHKLLTAVSPWVGEVDLLCARPRPAMRPRRADGIRRQLQGAHLASTPVFALLIQLFQIDVTGCMEVVRERKAWPPALLQAGAGDPLPLQEPSSAHSAPGCLTQSVPAQGAAKQSTCPEGGRGPQACCTASMPRAAAPAPCRPRPKPKTVSELLREKRLREARARRAAQGPAVLSARVLVSTPMVLQPLAPPGASVSRVVLSGPGGPPVTSSSVSGSWAPVKNERAPTLHAFALSPATSRAPGQVPASCPLSALGQSQAPATSRKQGLPEAPPLLPAAPSPVQLPVQPLSLTPALGMPAAASTPLPVTWVLTAQGLLPVPLQAMVSLPPPTGAPDPTQLSVILPPSPTETRASRGPRLPEQSRPGPPAASTDLEPEPPCRTEPLSKSPTEVAEACGLAELTSHEEEALVSGETSAPRTPSQDTPLAHHPATGPPSSSPQPLHGAPGAASGPREPQPLDLEEPQPLDLEEPLLPWLGLENGPLDLSLLSQESEVATQEWLRGQQGVPVPALGSQLAYQPPTLCSLRALSGLLLRKKDLEHGAAVLAPGGPAGALQASLGRVRERLHDSPAYLLLRARFLAAFTLPALLATLSPRGVPTTLSASTGPDPETDSDDFDPEEPELTDSDGQPGDPAQGAPDPSQGSAPSCPDSPDNLDVLQTRRSRHVRKRRRLQ", "length": 1351 }, "evidence": [ { "id": "A0A8V1ACK4", "url": "https://omabrowser.org/oma/group/A0A8V1ACK4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1LYZ6-1", "protein_name": "snRNA-activating protein complex subunit 4", "gene_name": "Snapc4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDIDAEREKVTQEIQELERILYPGSSSVHFEVSESSLSSDSEADPLPDEDLETAGAPVLEEERSSEGSNDDEDPKDKALPEDPETCLQLNMVYQEVIREKLAEVSQLLAQNQEQQEEILFDLAGTKCPKVKDAKSLPSYMYIGHFLKPYFKDKVTGVGPPANEETREKAAQGIKAFEQLLVTKWKHWEKDLLRKSVVSDRLQRLLQPKLLKLEYLQEKQSRVSSELEKQALEKQIKEAEKEIQDINQLPEEALLGNRLDSHDWEKISNVNFEGARSAEEIRKFWQSSEHPSINKKEWSTEEVERLKTIAASHGHLEWHLVAEELGTSRSAFQCLQKFQQYNKALKRKEWTEEEDHMLTQLVQEMRVGNHIPYRRIVYFMEGRDSMQLIYRWTKSLDPSLKRGFWAPEEDAKLLQAVAKYGAQDWFKIREEVPGRSDAQCRDRYIRRLHFSLKKGRWDAKEEQQLIQLIEKYGVGHWARIASELPHRSGSQCLSKWKILARKKQHLQKRRGQRSRHSSQWSSCSSSSSSSSSSSGSEDYGGGSSSSSNSSEDSEVELEEPLQNSRALAPQQYSVPDIDLWVPTRLIDSRSQREETGCYPVHPAVSCRTQNHHKEGSTVVSAPERNQMQECCETHSTVPRGVQSLHSSDTHGASVKEPACKSHTLVKERRRQPPLPNSRSGSDPGNSMAGPHLRRLWHGTFQNKQRRKRQALHRRLLKHRLLLAVIPWVGDINLACTQAVQRPAAVQTQADSIRMQLECARLASTPVFTLFIQLLQIDTAGCMEVVQERKTQPPALLQPGTRNTQPHLLQASSNAKNNTGCLLPGMLDEQTAKRTSQKGRPRLGSCKAEATPFQVPVAAPRGLRPKPKTVSELLREKRLRESHAKKATQALTALSSQLLVSSPVLLQPPLLPAARGSPVVGPAASSVELSVPVAPVMVSSSPSGSWQVGGISATDKQPPNLQTIPLNPSHKGTQIAAPAAFRSLALASGHVSTGCPLNTLGQTSTTSQKQSLPKVLPILPAAPSLTQLSVQPLSLPPVLNPPASGQPPATKSSLPVSWVLTTQKLLSVQVPAVVGLPQPVTTPETIGLQAKQLPSPSKTPAFLGQPPASTDTEPKGPQGQQTPPTPGPEKKALDLSLLSQESEAAILTWLTGSQGACVPPLGSRMSYHPPSLCSLRALSSLLLHKKDLEQKASSLVAGQAAGAQPEPKAGALQASLELVQRQFQNNPAYLLLKTRFLAIFSLPAFLATLPPNSVPTTLSPAMAVGSESDSEDFGDLEPRDGATQLDCMACRVRANLMAPDPVVSHLPSWERRAPSPSAVSAPSHLDASDDLDDLDVLRTRHARHSRK", "length": 1345 }, "evidence": [ { "id": "A0A8V1ACK4", "url": "https://omabrowser.org/oma/group/A0A8V1ACK4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5SXM2-1", "protein_name": "snRNA-activating protein complex subunit 4", "gene_name": "SNAPC4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDVDAEREKITQEIKELERILDPGSSGSHVEISESSLESDSEADSLPSEDLDPADPPISEEERWGEASNDEDDPKDKTLPEDPETCLQLNMVYQEVIQEKLAEANLLLAQNREQQEELMRDLAGSKGTKVKDGKSLPPSTYMGHFMKPYFKDKVTGVGPPANEDTREKAAQGIKAFEELLVTKWKNWEKALLRKSVVSDRLQRLLQPKLLKLEYLHQKQSKVSSELERQALEKQGREAEKEIQDINQLPEEALLGNRLDSHDWEKISNINFEGSRSAEEIRKFWQNSEHPSINKQEWSREEEERLQAIAAAHGHLEWQKIAEELGTSRSAFQCLQKFQQHNKALKRKEWTEEEDRMLTQLVQEMRVGSHIPYRRIVYYMEGRDSMQLIYRWTKSLDPGLKKGYWAPEEDAKLLQAVAKYGEQDWFKIREEVPGRSDAQCRDRYLRRLHFSLKKGRWNLKEEEQLIELIEKYGVGHWAKIASELPHRSGSQCLSKWKIMMGKKQGLRRRRRRARHSVRWSSTSSSGSSSGSSGGSSSSSSSSSEEDEPEQAQAGEGDRALLSPQYMVPDMDLWVPARQSTSQPWRGGAGAWLGGPAASLSPPKGSSASQGGSKEASTTAAAPGEETSPVQVPARAHGPVPRSAQASHSADTRPAGAEKQALEGGRRLLTVPVETVLRVLRANTAARSCTQKEQLRQPPLPTSSPGVSSGDSVARSHVQWLRHRATQSGQRRWRHALHRRLLNRRLLLAVTPWVGDVVVPCTQASQRPAVVQTQADGLREQLQQARLASTPVFTLFTQLFHIDTAGCLEVVRERKALPPRLPQAGARDPPVHLLQASSSAQSTPGHLFPNVPAQEASKSASHKGSRRLASSRVERTLPQASLLASTGPRPKPKTVSELLQEKRLQEARAREATRGPVVLPSQLLVSSSVILQPPLPHTPHGRPAPGPTVLNVPLSGPGAPAAAKPGTSGSWQEAGTSAKDKRLSTMQALPLAPVFSEAEGTAPAASQAPALGPGQISVSCPESGLGQSQAPAASRKQGLPEAPPFLPAAPSPTPLPVQPLSLTHIGGPHVATSVPLPVTWVLTAQGLLPVPVPAVVSLPRPAGTPGPAGLLATLLPPLTETRAAQGPRAPALSSSWQPPANMNREPEPSCRTDTPAPPTHALSQSPAEADGSVAFVPGEAQVAREIPEPRTSSHADPPEAEPPWSGRLPAFGGVIPATEPRGTPGSPSGTQEPRGPLGLEKLPLRQPGPEKGALDLEKPPLPQPGPEKGALDLGLLSQEGEAATQQWLGGQRGVRVPLLGSRLPYQPPALCSLRALSGLLLHKKALEHKATSLVVGGEAERPAGALQASLGLVRGQLQDNPAYLLLRARFLAAFTLPALLATLAPQGVRTTLSVPSRVGSESEDEDLLSELELADRDGQPGCTTATCPIQGAPDSGKCSASSCLDTSNDPDDLDVLRTRHARHTRKRRRLV", "length": 1469 }, "evidence": [ { "id": "A0A8V1ACK4", "url": "https://omabrowser.org/oma/group/A0A8V1ACK4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BP86-1", "protein_name": "snRNA-activating protein complex subunit 4", "gene_name": "Snapc4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDIDAEREKITQEIQELERILYPGSTSVHFEVSESSLSSDSEADSLPDEDLETAGAPILEEEGSSESSNDEEDPKDKALPEDPETCLQLNMVYQEVIREKLAEVSQLLAQNQEQQEEILFDLSGTKCPKVKDGRSLPSYMYIGHFLKPYFKDKVTGVGPPANEETREKATQGIKAFEQLLVTKWKHWEKALLRKSVVSDRLQRLLQPKLLKLEYLHEKQSRVSSELERQALEKQIKEAEKEIQDINQLPEEALLGNRLDSHDWEKISNINFEGARSAEEIRKFWQSSEHPSISKQEWSTEEVERLKAIAATHGHLEWHLVAEELGTSRSAFQCLQKFQQYNKTLKRKEWTEEEDHMLTQLVQEMRVGNHIPYRKIVYFMEGRDSMQLIYRWTKSLDPSLKRGFWAPEEDAKLLQAVAKYGAQDWFKIREEVPGRSDAQCRDRYIRRLHFSLKKGRWNAKEEQQLIQLIEKYGVGHWARIASELPHRSGSQCLSKWKILARKKQHLQRKRGQRPRHSSQWSSSGSSSSSSEDYGSSSGSDGSSGSENSDVELEASLEKSRALTPQQYRVPDIDLWVPTRLITSQSQREGTGCYPQHPAVSCCTQDASQNHHKEGSTTVSAAEKNQLQVPYETHSTVPRGDRFLHFSDTHSASLKDPACKSHTLMKERPKQPLLPSSRSGSDPGNNTAGPHLRQLWHGTYQNKQRRKRQALHRRLLKHRLLLAVIPWVGDINLACTQAPRRPATVQTKADSIRMQLECARLASTPVFTLLIQLLQIDTAGCMEVVRERKSQPPALLQPGTRNTQPHLLQASSNAKNNTGCLPSMTGEQTAKRASHKGRPRLGSCRTEATPFQVPVAAPRGLRPKPKTVSELLREKRLRESHAKKATQALGLNSQLLVSSPVILQPPLLPVPHGSPVVGPATSSVELSVPVAPVMVSSSPSGSWPVGGISATDKQPPNLQTISLNPPHKGTQVAAPAAFRSLALAPGQVPTGGHLSTLGQTSTTSQKQSLPKVLPILRAAPSLTQLSVQPPVSGQPLATKSSLPVNWVLTTQKLLSVQVPAVVGLPQSVMTPETIGLQAKQLPSPAKTPAFLEQPPASTDTEPKGPQGQEIPPTPGPEKAALDLSLLSQESEAAIVTWLKGCQGAFVPPLGSRMPYHPPSLCSLRALSSLLLQKQDLEQKASSLAASQAAGAQPDPKAGALQASLELVQRQFRDNPAYLLLKTRFLAIFSLPAFLATLPPNSIPTTLSPDVAVVSESDSEDLGDLELKDRARQLDCMACRVQASPAAPDPVQSHLVSPGQRAPSPGEVSAPSPLDASDGLDDLNVLRTRRARHSRR", "length": 1333 }, "evidence": [ { "id": "A0A8V1ACK4", "url": "https://omabrowser.org/oma/group/A0A8V1ACK4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "snRNA-activating protein complex", "id": "GO:0019185", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019185", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACK4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "snRNA transcription by RNA polymerase II", "id": "GO:0042795", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042795", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACK4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK4" } ], "pmid": "" }, { "name": "snRNA transcription by RNA polymerase III", "id": "GO:0042796", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042796", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACK4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "RNA polymerase II general transcription initiation factor activity", "id": "GO:0016251", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016251", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACK4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK4" } ], "pmid": "" }, { "name": "RNA polymerase III type 3 promoter sequence-specific DNA binding", "id": "GO:0001006", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001006", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACK4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK4" } ], "pmid": "" }, { "name": "RNA polymerase III general transcription initiation factor activity", "id": "GO:0000995", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000995", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACK4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1232, "end_pos": 1234, "annotation": "n_glycosylation_sequon" }, { "start_pos": 327, "end_pos": 329, "annotation": "n_glycosylation_sequon" }, { "start_pos": 804, "end_pos": 806, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1ACK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK4" }, { "id": "PS51294", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51294" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "HTH myb-type", "eco_id": "ECO_0000259", "start_pos": 289, "end_pos": 345, "start_aa": "His", "end_aa": "Lys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1ACK4", 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This record is derived from a genomic sequence (NC_052533.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. 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"Protein Classification" ] }, { "id": "IPR029044", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029044", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050486", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050486", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056729", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056729", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ACT2", "url": "https://www.orthodb.org/?gene=A0A8V1ACT2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22572", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22572", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00483", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00483", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25087", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25087", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-446205", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-446205", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1ACT2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACT2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ACT2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACT2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "ATCPRRWRPPCASRSSGSASASPCPTRRSRWAQRLSDSRRPGAVVAPGTPRRAQAAPGPRLGCPRPRGDTDSRAAGPLALARDLLAEGGEPFFVLNSDVICEFPFAALARFHRQHGGEGSIVVTRVEEPAKYGVVVSEPDSGRICRFVEKPRVFVSNKINAGLYIFSPGILQRIQLRPTSIEKEIFPAMAQDGQLYAMELQGFWMDIGQPKDFLTGMCMYLQALRAQHPEKLHSGPGVVGNVLVDPSAKIGANCVIGPNVTIGAGVVVEDGVRIKRCTVLQGARIRSHSWLESCIVGWSCSVGQWVRMENVTVLGEDVIVNDELYLNGANVLPHKSIAESVPEPRIIM", "length": 348, "header": "tr|A0A8V1ACT2-1|A0A8V1ACT2_CHICK Isoform 1 of mannose-1-phosphate guanylyltransferase OS=Gallus gallus OX=9031 GN=GMPPB PE=1 SV=1 CANONICAL=A0A8V1ACT2-1" }, "isoforms": [ { "isoform_ac": "A0A8V1ACT2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACT2/entry#A0A8V1ACT2-1", "sequence": { "sequence": "ATCPRRWRPPCASRSSGSASASPCPTRRSRWAQRLSDSRRPGAVVAPGTPRRAQAAPGPRLGCPRPRGDTDSRAAGPLALARDLLAEGGEPFFVLNSDVICEFPFAALARFHRQHGGEGSIVVTRVEEPAKYGVVVSEPDSGRICRFVEKPRVFVSNKINAGLYIFSPGILQRIQLRPTSIEKEIFPAMAQDGQLYAMELQGFWMDIGQPKDFLTGMCMYLQALRAQHPEKLHSGPGVVGNVLVDPSAKIGANCVIGPNVTIGAGVVVEDGVRIKRCTVLQGARIRSHSWLESCIVGWSCSVGQWVRMENVTVLGEDVIVNDELYLNGANVLPHKSIAESVPEPRIIM", "length": 348, "header": "tr|A0A8V1ACT2-1|A0A8V1ACT2_CHICK Isoform 1 of mannose-1-phosphate guanylyltransferase OS=Gallus gallus OX=9031 GN=GMPPB PE=1 SV=1 CANONICAL=A0A8V1ACT2-1" }, "locus": { "chromosome": "12", "start_pos": 2550486, "end_pos": 2548656, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068270.1", "url": "https://www.ensembl.org/id/ENSGALT00010068270.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042013.1", "url": "https://www.ensembl.org/id/ENSGALP00010042013.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-GGA-446205", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-446205", "resource": "Reactome", "description": "Synthesis of GDP-mannose" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "mannose-1-phosphate guanylyltransferase (GTP) activity", "id": "GO:0004475", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004475", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACT2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACT2" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACT2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACT2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACT2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACT2" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACT2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACT2" } ], "pmid": "" }, { "name": "GDP-mannose pyrophosphorylase complex", "id": "GO:0120508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120508", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACT2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACT2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "GDP-mannose biosynthetic process", "id": "GO:0009298", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009298", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACT2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACT2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 259, "end_pos": 261, "annotation": "n_glycosylation_sequon" }, { "start_pos": 310, "end_pos": 312, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-GGA-446221", "name": "GMPPB converts Mannose-1-phosphate to GDP-Mannose", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-ALL-532531", "R-ALL-29438" ], "output_participant_list": [], "enzyme_list": [ "A0A8V1ACT2-1" ], "evidence": [ { "id": "R-GGA-446221", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-446221" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-29438", "participant_name": "GTP [cytosol]", "crossref": [ { "id": "37565", "database": "ChEBI", "url": "" }, { "id": "ZINC000060094177", "database": "ZINC", "url": "" }, { "id": "C00044", "database": "COMPOUND", "url": "" } ] }, { "participant_id": "R-ALL-532531", "participant_name": "Man1P [cytosol]", "crossref": [ { "id": "58409", "database": "ChEBI", "url": "" }, { "id": "ZINC000004095569", "database": "ZINC", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A8V1ACT2", "gene_name": "GMPPB", "activity": [ { "ec_number": "2.7.7.13", "activity": "alpha-D-mannose 1-phosphate + GTP + H(+) = GDP-alpha-D-mannose + diphosphate.", "evidence": [ { "id": "A0A8V1ACT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACT2" } ] }, { "ec_number": "2.7.7.13", "activity": "", "evidence": [ { "id": "A0A8V1ACT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACT2" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1ACT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACT2" }, { "id": "PF25087", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25087" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Mannose-1-phosphate guanyltransferase C-terminal", "eco_id": "ECO_0000259", "start_pos": 238, "end_pos": 347, "start_aa": "Val", "end_aa": "Ile", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1ACT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACT2" }, { "id": "PF00483", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00483" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Nucleotidyl transferase", "eco_id": "ECO_0000259", "start_pos": 74, "end_pos": 221, "start_aa": "Ala", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.7.7.13", "ec_name": "alpha-D-mannose 1-phosphate + GTP + H(+) = GDP-alpha-D-mannose + diphosphate.", "evidence": [ { "id": "2.7.7.13", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.13" }, { "id": "2.7.7.13", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.7.7.13" } ] } ], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 259, "end_pos": 261 }, { "start_pos": 310, "end_pos": 312 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1ACU3-1", "uniprot_ac": "A0A8V1ACU3", "uniprot_id": "A0A8V1ACU3_CHICK", "mass": { "chemical_mass": 139618.0, "monoisotopic_mass": 139618.0 }, "refseq": {}, "gene_names": [ { "name": "UBE2O", "type": "recommended", "evidence": [ { "id": "A0A8V1ACU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACU3" } ] } ], "protein_names": [ { "name": "(E3-independent) E2 ubiquitin-conjugating enzyme", "type": "recommended", "evidence": [ { "id": "A0A8V1ACU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACU3/entry#names_and_taxonomy" } ] }, { "name": "2.3.2.24", "type": "synonym", "evidence": [ { "id": "A0A8V1ACU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACU3/entry#names_and_taxonomy" } ] }, { "name": "E2/E3 hybrid ubiquitin-protein ligase UBE2O", "type": "synonym", "evidence": [ { "id": "A0A8V1ACU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACU3/entry#names_and_taxonomy" } ] }, { "name": "Ubiquitin carrier protein O", "type": "synonym", "evidence": [ { "id": "A0A8V1ACU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACU3/entry#names_and_taxonomy" } ] }, { "name": "Ubiquitin-conjugating enzyme E2 O", "type": "synonym", "evidence": [ { "id": "A0A8V1ACU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACU3/entry#names_and_taxonomy" } ] }, { "name": "Ubiquitin-conjugating enzyme E2 of 230 kDa", "type": "synonym", "evidence": [ { "id": "A0A8V1ACU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACU3/entry#names_and_taxonomy" } ] }, { "name": "Ubiquitin-protein ligase O", "type": "synonym", "evidence": [ { "id": "A0A8V1ACU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACU3/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "E2/E3 hybrid ubiquitin-protein ligase that displays both E2 and E3 ligase activities and mediates monoubiquitination of target proteins. Negatively regulates TRAF6-mediated NF-kappa-B activation independently of its E2 activity. Acts as a positive regulator of BMP7 signaling by mediating monoubiquitination of SMAD6, thereby regulating adipogenesis. Mediates monoubiquitination at different sites of the nuclear localization signal (NLS) of BAP1, leading to cytoplasmic retention of BAP1. Also able to monoubiquitinate the NLS of other chromatin-associated proteins, such as INO80 and CXXC1, affecting their subcellular location. Acts as a regulator of retrograde transport by assisting the TRIM27:MAGEL2 E3 ubiquitin ligase complex to mediate 'Lys-63'-linked ubiquitination of WASHC1, leading to promote endosomal F-actin assembly.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACU3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACU3#function" }, { "database": "UniProtKB", "id": "ARBA00057012", "url": "https://www.uniprot.org/uniprotkb/ARBA00057012#function" }, { "database": "UniProtKB", "id": "A0A8V1AK34", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK34#function" }, { "database": "UniProtKB", "id": "A0A8V1AM30", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM30#function" }, { "database": "UniProtKB", "id": "A0A8V1ANM1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANM1#function" }, { "database": "UniProtKB", "id": "A0A8V1AI48", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI48#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACU3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACU3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "UBE2O", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACU3", "locus": { "chromosome": "18", "start_pos": 5051863, "end_pos": 5003899, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029407", "url": "https://www.ensembl.org/id/ENSGALG00010029407" } ] } } ], "crossref": [ { "id": "A0A8V1ACU3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1ACU3", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd23837", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd23837", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000608", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000608", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016135", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016135", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057732", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057732", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057733", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057733", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057734", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057734", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057735", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057735", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ACU3", "url": "https://www.orthodb.org/?gene=A0A8V1ACU3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AI48", "url": "https://www.orthodb.org/?gene=A0A8V1AI48", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AK34", "url": "https://www.orthodb.org/?gene=A0A8V1AK34", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AM30", "url": "https://www.orthodb.org/?gene=A0A8V1AM30", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ANM1", "url": "https://www.orthodb.org/?gene=A0A8V1ANM1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46116", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46116", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46116:SF15", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46116:SF15", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00179", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00179", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23043", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23043", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23044", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23044", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23046", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23046", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23048", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23048", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-983168", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983168", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1ACU3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACU3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ACU3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACU3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AI48", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI48", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AI48-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI48-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AK34", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK34", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AK34-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK34-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AM30", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM30", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AM30-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM30-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ANM1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANM1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ANM1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANM1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "CIQAGRPSPRPSLPARTRIAAAGSGRAAPAPAAPTPAPALPLPPSAPPGGSQRLLFSHDLVSGRYRGSVRFGLVRLIHGEDSDSEEEETSGGPGAGGTEEGRASPLRRGYVRVQWYPEGIKQHVKETKLKLEDRSVVPRDVVRHMSSSDSQCGTVIDVNIECAVKLVGTNCILYPVNSKDLQHIWPFMYGDYIAYDCWLGKVYDLKNQVILKLSNGARCSMSTEDGAKLYDVCPHVSDSGLFFDDSYGFYPGQVLIGPSKVFSSVQWLSGVKPVLSTKSKFRVVVEEVQVVELKVTWITKSFCPGGTDSVSPPPSIISQENLSRVKRLGCFDHAQRQLGERCLYVFPDKVEPAKITCECPERNCVLGEGSVAKKVRRLLKKQIVKIMSCSPESQGTTEAPDKEPAPAADQKAEDLKPGSKCELEDSSNGAPSAGERKEEQPEETGKDKGGAAVRQQQPPFLLKDEGSADYRLQSMEQDADDEAADDTDDTSSVTSSASSTASSQSGSGTGRKKSIPLSIKNLKRKHKKKKTKISREFKPGDRVAVEVVTTMTSADVMWQDGTVETNIRSNELIPVHHLDNNEFCPGDFVVDKRAQSSQDPGVYGVVQSGDHIGRTCVVKWFKLKSSGDDVELIGEEEDVSVYDIADHPDFRFRTTDIVIRIGNSDGATANEDEPSVGQVARVDVSSKVEVVWADNSKTIILPQHLYNIESEIEESDYDSVDGSTSGASSEWEDESDSWETDNGLMEDDHPRIEELEPEEPAAEEVKKVEEQVQGAVAMAVADLAAEKAGKDGILESLKNMTVEQLLTGSPTSPTVELEKPTREKKFLDDIKKLQENLKKTLDNVAIAEEEKMEAMVETEKKEEKAEAQTPVRSEWPSETPVLCQQSGGKPGVTFTSAKGEVFSVLECAPDSHAFKKMEFQPPEAKKFFSTVRKEMALLATSLPDGIMVKTFEDRMDLFSALIKGPTRTPYEDGLFLFDIQLPNIYPAVPPLFRYLSQCSGRLNPNLYDNGKVCVSLLGTWIGKGTERWTSKSSLLQVLISIQGLILVNEPYYNEAGFDSDRGLQEGYENSRCYNEMTLIRVVQSMMQLLRRPVEVFEHEIREHFRCNGWRLVSRIESWLETNELVERSHEQSNGLSGSAEQGAAAELSDSALDGKEELDEAEFATSAPNAGDVRQHSDSEGAGQGRGVGLARDRTDEGRAAQDSASQPSVKPKKRRKSYRSFLPEKSGYPDIGFPLFPLSKGFIKSIRGVLQQYRAALAGANIPEWTEDK", "length": 1270, "header": "tr|A0A8V1ACU3-1|A0A8V1ACU3_CHICK Isoform 1 of (E3-independent) E2 ubiquitin-conjugating enzyme OS=Gallus gallus OX=9031 GN=UBE2O PE=1 SV=1 CANONICAL=A0A8V1ACU3-1" }, "isoforms": [ { "isoform_ac": "A0A8V1ACU3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACU3/entry#A0A8V1ACU3-1", "sequence": { "sequence": "CIQAGRPSPRPSLPARTRIAAAGSGRAAPAPAAPTPAPALPLPPSAPPGGSQRLLFSHDLVSGRYRGSVRFGLVRLIHGEDSDSEEEETSGGPGAGGTEEGRASPLRRGYVRVQWYPEGIKQHVKETKLKLEDRSVVPRDVVRHMSSSDSQCGTVIDVNIECAVKLVGTNCILYPVNSKDLQHIWPFMYGDYIAYDCWLGKVYDLKNQVILKLSNGARCSMSTEDGAKLYDVCPHVSDSGLFFDDSYGFYPGQVLIGPSKVFSSVQWLSGVKPVLSTKSKFRVVVEEVQVVELKVTWITKSFCPGGTDSVSPPPSIISQENLSRVKRLGCFDHAQRQLGERCLYVFPDKVEPAKITCECPERNCVLGEGSVAKKVRRLLKKQIVKIMSCSPESQGTTEAPDKEPAPAADQKAEDLKPGSKCELEDSSNGAPSAGERKEEQPEETGKDKGGAAVRQQQPPFLLKDEGSADYRLQSMEQDADDEAADDTDDTSSVTSSASSTASSQSGSGTGRKKSIPLSIKNLKRKHKKKKTKISREFKPGDRVAVEVVTTMTSADVMWQDGTVETNIRSNELIPVHHLDNNEFCPGDFVVDKRAQSSQDPGVYGVVQSGDHIGRTCVVKWFKLKSSGDDVELIGEEEDVSVYDIADHPDFRFRTTDIVIRIGNSDGATANEDEPSVGQVARVDVSSKVEVVWADNSKTIILPQHLYNIESEIEESDYDSVDGSTSGASSEWEDESDSWETDNGLMEDDHPRIEELEPEEPAAEEVKKVEEQVQGAVAMAVADLAAEKAGKDGILESLKNMTVEQLLTGSPTSPTVELEKPTREKKFLDDIKKLQENLKKTLDNVAIAEEEKMEAMVETEKKEEKAEAQTPVRSEWPSETPVLCQQSGGKPGVTFTSAKGEVFSVLECAPDSHAFKKMEFQPPEAKKFFSTVRKEMALLATSLPDGIMVKTFEDRMDLFSALIKGPTRTPYEDGLFLFDIQLPNIYPAVPPLFRYLSQCSGRLNPNLYDNGKVCVSLLGTWIGKGTERWTSKSSLLQVLISIQGLILVNEPYYNEAGFDSDRGLQEGYENSRCYNEMTLIRVVQSMMQLLRRPVEVFEHEIREHFRCNGWRLVSRIESWLETNELVERSHEQSNGLSGSAEQGAAAELSDSALDGKEELDEAEFATSAPNAGDVRQHSDSEGAGQGRGVGLARDRTDEGRAAQDSASQPSVKPKKRRKSYRSFLPEKSGYPDIGFPLFPLSKGFIKSIRGVLQQYRAALAGANIPEWTEDK", "length": 1270, "header": "tr|A0A8V1ACU3-1|A0A8V1ACU3_CHICK Isoform 1 of (E3-independent) E2 ubiquitin-conjugating enzyme OS=Gallus gallus OX=9031 GN=UBE2O PE=1 SV=1 CANONICAL=A0A8V1ACU3-1" }, "locus": { "chromosome": "18", "start_pos": 5051860, "end_pos": 5003975, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071132.1", "url": "https://www.ensembl.org/id/ENSGALT00010071132.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043823.1", "url": "https://www.ensembl.org/id/ENSGALP00010043823.1" } ] } }, { "isoform_ac": "A0A8V1AI48-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACU3/entry#A0A8V1AI48-1", "sequence": { "sequence": "NKSTSHQCGTVIDVNIECAVKLVGTNCILYPVNSKDLQHIWPFMYGDYIAYDCWLGKVYDLKNQVILKLSNGARCSMSTEDGAKLYDVCPHVSDSGLFFDDSYGFYPGQVLIGPSKVFSSVQWLSGVKPVLSTKSKFRVVVEEVQVVELKVTWITKSFCPGGTDSVSPPPSIISQENLSRVKRLGCFDHAQRQLGERCLYVFPDKVEPAKITCECPERNCVLGEGSVAKKVRRLLKKQIVKIMSCSPESQGTTEAPDKEPAPAADQKAEDLKPGSKCELEDSSNGAPSAGERKEEQPEETGKDKGGAAVRQQQPPFLLKDEGSADYRLQSMEQDADDEAADDTDDTSSVTSSASSTASSQSGSGTGRKKSIPLSIKNLKRKHKKKKTKISREFKPGDRVAVEVVTTMTSADVMWQDGTVETNIRSNELIPVHHLDNNEFCPGDFVVDKRAQSSQDPGVYGVVQSGDHIGRTCVVKWFKLKSSGDDVELIGEEEDVSVYDIADHPDFRFRTTDIVIRIGNSDGATANEDEPSVGQVARVDVSSKVEVVWADNSKTIILPQHLYNIESEIEESDYDSVDGSTSGASSEWEDESDSWETDNGLMEDDHPRIEELEPEEPAAEEVKKVEEQVQGAVAMAVADLAAEKAGKDGILESLKNMTVEQLLTGSPTSPTVELEKPTREKKFLDDIKKLQENLKKTLDNVAIAEEEKMEAMVETEKKEEKAEAQTPVRSEWPSETPVLCQQSGGKPGVTFTSAKGEVFSVLECAPDSHAFKKMEFQPPEAKKFFSTVRKEMALLATSLPDGIMVKTFEDRMDLFSALIKGPTRTPYEDGLFLFDIQLPNIYPAVPPLFRYLSQCSGRLNPNLYDNGKVCVSLLGTWIGKGTERWTSKSSLLQVLISIQGLILVNEPYYNEAGFDSDRGLQEGYENSRCYNEMTLIRVVQSMMQLLRRPVEVFEHEIREHFRCNGWRLVSRIESWLETNELVERSHEQSNGADPASLLSQGAAAELSDSALDGKEELDEAEFATSAPNAGDVRQHSDSEGAGQGRGVGLARDRTDEGRAAQDSASQPSVKPKKRRKSYRSFLPEKSGYPDIGFPLFPLSKGFIKSIRGVLQQYRAALAGANIPEWTEDK", "length": 1128, "header": "tr|A0A8V1AI48-1|A0A8V1ACU3_CHICK Computationally mapped isoform of (E3-independent) E2 ubiquitin-conjugating enzyme OS=Gallus gallus OX=9031 GN=UBE2O PE=1 SV=1 CANONICAL=A0A8V1ACU3-1" }, "locus": { "chromosome": "18", "start_pos": 5051860, "end_pos": 5031322, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071129.1", "url": "https://www.ensembl.org/id/ENSGALT00010071129.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043820.1", "url": "https://www.ensembl.org/id/ENSGALP00010043820.1" } ] } }, { "isoform_ac": "A0A8V1AK34-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACU3/entry#A0A8V1AK34-1", "sequence": { "sequence": "MSSSDSQCGTVIDVNIECAVKLVGTNCILYPVNSKDLQHIWPFMYGDYIAYDCWLGKVYDLKNQVILKLSNGARCSMSTEDGAKLYDVCPHVSDSGLFFDDSYGFYPGQVLIGPSKVFSSVQWLSGVKPVLSTKSKFRVVVEEVQVVELKVTWITKSFCPGGTDSVSPPPSIISQENLSRVKRLGCFDHAQRQLGERCLYVFPDKVEPAKITCECPERNCVLGEGSVAKKVRRLLKKQIVKIMSCSPESQGTTEAPDKEPAPAADQKAEDLKPGSKCELEDSSNGAPSAGERKEEQPEETGKDKGGAAVRQQQPPFLLKDEGSADYRLQSMEQDADDEAADDTDDTSSVTSSASSTASSQSGSGTGRKKSIPLSIKNLKRKHKKKKTKISREFKPGDRVAVEVVTTMTSADVMWQDGTVETNIRSNELIPVHHLDNNEFCPGDFVVDKRAQSSQDPGVYGVVQSGDHIGRTCVVKWFKLKSSGDDVELIGEEEDVSVYDIADHPDFRFRTTDIVIRIGNSDGATANEDEPSVGQVARVDVSSKVEVVWADNSKTIILPQHLYNIESEIEESDYDSVDGSTSGASSEWEDESDSWETDNGLMEDDHPRIEELEPEEPAAEEVKKVEEQVQGAVAMAVADLAAEKAGKDGILESLKNMTVEQLLTGSPTSPTVELEKPTREKKFLDDIKKLQENLKKTLDNVAIAEEEKMEAMVETEKKEEKAEAQTPVRSEWPSETPVLCQQSGGKPGVTFTSAKGEVFSVLECAPDSHAFKKMEFQPPEAKKFFSTVRKEMALLATSLPDGIMVKTFEDRMDLFSALIKGPTRTPYEDGLFLFDIQLPNIYPAVPPLFRYLSQCSGRLNPNLYDNGKVCVSLLGTWIGKGTERWTSKSSLLQVLISIQGLILVNEPYYNEAGFDSDRGLQEGYENSRCYNEMTLIRVVQSMMQLLRRPVEVFEHEIREHFRCNGWRLVSRIESWLETNELVERSHEQSNGLSGSAEQGAAAELSDSALDGKEELDEAEFATSAPNAGDVRQHSDSEGAGQGRGVGLARDRTDEGRAAQDSASQPSVKPKKRRKSYRSFLPEKSGYPDIGFPLFPLSKGFIKSIRGVLQQYRAALAGANIPEWTEDK", "length": 1126, "header": "tr|A0A8V1AK34-1|A0A8V1ACU3_CHICK Computationally mapped isoform of (E3-independent) E2 ubiquitin-conjugating enzyme OS=Gallus gallus OX=9031 GN=UBE2O PE=1 SV=1 CANONICAL=A0A8V1ACU3-1" }, "locus": { "chromosome": "18", "start_pos": 5051860, "end_pos": 5027902, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071131.1", "url": "https://www.ensembl.org/id/ENSGALT00010071131.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043822.1", "url": "https://www.ensembl.org/id/ENSGALP00010043822.1" } ] } }, { "isoform_ac": "A0A8V1AM30-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACU3/entry#A0A8V1AM30-1", "sequence": { "sequence": "MPGRGLQHARWKCSQPGLNNLHGSDSGLRGVLAPNRRWDELSTSKLTAFQKGCPGLWSVCICVQGLLLVLNPSPLLCFQDSQCGTVIDVNIECAVKLVGTNCILYPVNSKDLQHIWPFMYGDYIAYDCWLGKVYDLKNQVILKLSNGARCSMSTEDGAKLYDVCPHVSDSGLFFDDSYGFYPGQVLIGPSKVFSSVQWLSGVKPVLSTKSKFRVVVEEVQVVELKVTWITKSFCPGGTDSVSPPPSIISQENLSRVKRLGCFDHAQRQLGERCLYVFPDKVEPAKITCECPERNCVLGEGSVAKKVRRLLKKQIVKIMSCSPESQGTTEAPDKEPAPAADQKAEDLKPGSKCELEDSSNGAPSAGERKEEQPEETGKDKGGAAVRQQQPPFLLKDEGSADYRLQSMEQDADDEAADDTDDTSSVTSSASSTASSQSGSGTGRKKSIPLSIKNLKRKHKKKKTKISREFKPGDRVAVEVVTTMTSADVMWQDGTVETNIRSNELIPVHHLDNNEFCPGDFVVDKRAQSSQDPGVYGVVQSGDHIGRTCVVKWFKLKSSGDDVELIGEEEDVSVYDIADHPDFRFRTTDIVIRIGNSDGATANEDEPSVGQVARVDVSSKVEVVWADNSKTIILPQHLYNIESEIEESDYDSVDGSTSGASSEWEDESDSWETDNGLMEDDHPRIEELEPEEPAAEEVKKVEEQVQGAVAMAVADLAAEKAGKDGILESLKNMTVEQLLTGSPTSPTVELEKPTREKKFLDDIKKLQENLKKTLDNVAIAEEEKMEAMVETEKKEEKAEAQTPVRSEWPSETPVLCQQSGGKPGVTFTSAKGEVFSVLECAPDSHAFKKMEFQPPEAKKFFSTVRKEMALLATSLPDGIMVKTFEDRMDLFSALIKGPTRTPYEDGLFLFDIQLPNIYPAVPPLFRYLSQCSGRLNPNLYDNGKVCVSLLGTWIGKGTERWTSKSSLLQVLISIQGLILVNEPYYNEAGFDSDRGLQEGYENSRCYNEMTLIRVVQSMMQLLRRPVEVFEHEIREHFRCNGWRLVSRIESWLETNELVERSHEQSNGLSGSAEQGAAAELSDSALDGKEELDEAEFATSAPNAGDVRQHSDSEGAGQGRGVGLARDRTDEGRAAQDSASQPSVKPKKRRKSYRSFLPEKSGYPDIGFPLFPLSKGFIKSIRGVLQQYRAALAGANIPEWTEDK", "length": 1201, "header": "tr|A0A8V1AM30-1|A0A8V1ACU3_CHICK Computationally mapped isoform of (E3-independent) E2 ubiquitin-conjugating enzyme OS=Gallus gallus OX=9031 GN=UBE2O PE=1 SV=1 CANONICAL=A0A8V1ACU3-1" }, "locus": { "chromosome": "18", "start_pos": 5051860, "end_pos": 5031086, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071130.1", "url": "https://www.ensembl.org/id/ENSGALT00010071130.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043821.1", "url": "https://www.ensembl.org/id/ENSGALP00010043821.1" } ] } }, { "isoform_ac": "A0A8V1ANM1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACU3/entry#A0A8V1ANM1-1", "sequence": { "sequence": "AAALSFGGTAATAVLHLPLASPRGSVHPSRAAVPPGQRPRGGSSAPRTGIGPETNGRLLFSHDLVSGRYRGSVRFGLVRLIHGEDSDSEEEETSGGPGAGGTEEGRASPLRRGYVRVQWYPEGIKQHVKETKLKLEDRSVVPRDVVRHMSSSDSQCGTVIDVNIECAVKLVGTNCILYPVNSKDLQHIWPFMYGDYIAYDCWLGKVYDLKNQVILKLSNGARCSMSTEDGAKLYDVCPHVSDSGLFFDDSYGFYPGQVLIGPSKVFSSVQWLSGVKPVLSTKSKFRVVVEEVQVVELKVTWITKSFCPGGTDSVSPPPSIISQENLSRVKRLGCFDHAQRQLGERCLYVFPDKVEPAKITCECPERNCVLGEGSVAKKVRRLLKKQIVKIMSCSPESQGTTEAPDKEPAPAADQKAEDLKPGSKCELEDSSNGAPSAGERKEEQPEETGKDKGGAAVRQQQPPFLLKDEGSADYRLQSMEQDADDEAADDTDDTSSVTSSASSTASSQSGSGTGRKKSIPLSIKNLKRKHKKKKTKISREFKPGDRVAVEVVTTMTSADVMWQDGTVETNIRSNELIPVHHLDNNEFCPGDFVVDKRAQSSQDPGVYGVVQSGDHIGRTCVVKWFKLKSSGDDVELIGEEEDVSVYDIADHPDFRFRTTDIVIRIGNSDGATANEDEPSVGQVARVDVSSKVEVVWADNSKTIILPQHLYNIESEIEESDYDSVDGSTSGASSEWEDESDSWETDNGLMEDDHPRIEELEPEEPAAEEVKKVEEQVQGAVAMAVADLAAEKAGKDGILESLKNMTVEQLLTGSPTSPTVELEKPTREKKFLDDIKKLQENLKKTLDNVAIAEEEKMEAMVETEKKEEKAEAQTPVRSEWPSETPVLCQQSGGKPGVTFTSAKGEVFSVLECAPDSHAFKKMEFQPPEAKKFFSTVRKEMALLATSLPDGIMVKTFEDRMDLFSALIKGPTRTPYEDGLFLFDIQLPNIYPAVPPLFRYLSQCSGRLNPNLYDNGKVCVSLLGTWIGKGTERWTSKSSLLQVLISIQGLILVNEPYYNEAGFDSDRGLQEGYENSRCYNEMTLIRVVQSMMQLLRRPVEVFEHEIREHFRCNGWRLVSRIESWLETNELVERSHEQSNGADPASLLSAGSALADSPGDTAEFATSAPNAGDVRQHSDSEGAGQGRGVGLARDRTDEGRAAQDSASQPSVKPKKRRKSYRSFLPEKSGYPDIGFPLFPLSKGFIKSIRGVLQQYRAALAGANIPEWTEDK", "length": 1268, "header": "tr|A0A8V1ANM1-1|A0A8V1ACU3_CHICK Computationally mapped isoform of (E3-independent) E2 ubiquitin-conjugating enzyme OS=Gallus gallus OX=9031 GN=UBE2O PE=1 SV=1 CANONICAL=A0A8V1ACU3-1" }, "locus": { "chromosome": "18", "start_pos": 5051860, "end_pos": 5003899, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071133.1", "url": "https://www.ensembl.org/id/ENSGALT00010071133.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043824.1", "url": "https://www.ensembl.org/id/ENSGALP00010043824.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 35, "start_aa": "Thr", "end_pos": 35, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr35", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-GGA-983168", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983168", "resource": "Reactome", "description": "Antigen processing: Ubiquitination & Proteasome degradation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACU3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACU3" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACU3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACU3" } ], "pmid": "" }, { "name": "ubiquitin conjugating enzyme activity", "id": "GO:0061631", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061631", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACU3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACU3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACU3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACU3" } ], "pmid": "" }, { "name": "nuclear body", "id": "GO:0016604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016604", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACU3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACU3" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACU3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACU3" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACU3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACU3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "positive regulation of BMP signaling pathway", "id": "GO:0030513", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030513", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACU3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACU3" } ], "pmid": "" }, { "name": "retrograde transport, endosome to Golgi", "id": "GO:0042147", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042147", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACU3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACU3" } ], "pmid": "" }, { "name": "protein K63-linked ubiquitination", "id": "GO:0070534", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070534", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACU3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACU3" } ], "pmid": "" }, { "name": "protein monoubiquitination", "id": "GO:0006513", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006513", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACU3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACU3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 321, "end_pos": 323, "annotation": "n_glycosylation_sequon" }, { "start_pos": 799, "end_pos": 801, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-GGA-983140", "name": "Transfer of Ub from E2 to substrate and release of E2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0X324-1", "A0A8V0XEM6-1", "A0A8V0XJC4-1", "A0A8V0XQR1-1", "A0A8V1AC19-1", "A0A8V1AC55-1", "A0A8V1AKB8-1", "A0A8V1ALH0-1", "F1NL19-1", "F1NRC6-1", "F1NTZ8-1", "A0A8V0YHL7-1", "A0A8V0YPW4-1", "A0A8V0YRM6-1", "A0A8V0YV22-1", "A0A8V0YVP3-1", "A0A8V0Z2L5-1", "F1NL77-1", "E1C982-1", "A0A3Q2UC96-1", "Q5ZKX6-1", "Z4YJC3-1", "A0A8V0XQU7-1", "A0A8V0Y5C9-1", "A0A8V1AL09-1", "A0A8V1AML5-1", "A0A8V1AP69-1", "F1NVY8-1", "R4GIV8-1", "A0A8V0ZJ49-1", "A0A8V0ZJV9-1", "A0A8V0ZL18-1", "A0A8V0ZM17-1", "A0A8V0ZSH4-1", "A0A8V0ZVX3-1", "A0A8V0ZW26-1", "A0A8V1A0Z6-1", "A0A8V0ZZH3-1", "A0A8V1A052-1", "A0A8V1A0X2-1", "A0A8V1A1I4-1", "A0A8V1A2W7-1", "A0A8V1A5P4-1", "A0A8V1A7T1-1", "A0A8V0XTY5-1", "A0A8V0Y5B5-1", "A0A8V0YL05-1", "A0A8V0Z082-1", "A0A8V0ZS27-1", "A0A8V1A9M0-1", "E1BZ35-1", "E1C3Q9-1", "F1NC08-1", "F1P2G0-1", "A0A8V0YY10-1", "A0A8V0YYC5-1", "A0A8V0Z1W7-1", "A0A8V0Z4C8-1", "A0A8V0Z596-1", "A0A1D5P284-1", "A0A8V0ZF21-1", "A0A3Q2U2G8-1", "A0A8V1A4H7-1", "A0A8V1A1N8-1", "A0A8V1A233-1", "A0A8V1A7P9-1", "A0A8V1ACU3-1", "A0A8V0ZSA3-1", "E1C656-1", "A0A8V0Y0Q7-1", "A0A8V0Y059-1", "A0A8V0Y5C7-1", "A0A8V0YCS7-1", "A0A8V0YDQ1-1", "A0A8V0YFD9-1", "A0A8V0YGF4-1", "A0A8V0YJK8-1", "A0A8V0YLY7-1", "A0A1D5NVE2-1", "A0A8V0ZKK3-1", "A0A8V0ZKQ3-1" ], "evidence": [ { "id": "R-GGA-983140", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983140" } ] }, { "id": "R-GGA-983152", "name": "Transfer of ubiquitin from E1 to E2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0X324-1", "A0A8V0XQR1-1", "A0A8V1AC19-1", "F1NL19-1", "A0A8V0YPW4-1", "Q5ZKX6-1", "R4GIV8-1", "A0A8V0ZBK2-1", "A0A8V1A052-1", "A0A8V1A1I4-1", "A0A8V1A5P4-1", "A0A8V0Z082-1", "A0A8V0YY10-1", "A0A8V0Z1W7-1", "A0A8V0XNP1-1", "A0A8V1A4H7-1", "A0A8V1ACU3-1", "A0A8V0Y059-1", "A0A8V0YFD9-1", "A0A1D5NVE2-1" ], "evidence": [ { "id": "R-GGA-983152", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983152" } ] }, { "id": "R-GGA-983156", "name": "Polyubiquitination of substrate", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0X324-1", "A0A8V0XEM6-1", "A0A8V0XJC4-1", "A0A8V0XQR1-1", "A0A8V1AC19-1", "A0A8V1AC55-1", "A0A8V1AKB8-1", "A0A8V1ALH0-1", "F1NL19-1", "F1NRC6-1", "F1NTZ8-1", "A0A8V0YHL7-1", "A0A8V0YPW4-1", "A0A8V0YRM6-1", "A0A8V0YV22-1", "A0A8V0YVP3-1", "A0A8V0Z2L5-1", "F1NL77-1", "E1C982-1", "A0A3Q2UC96-1", "Q5ZKX6-1", "Z4YJC3-1", "A0A8V0XQU7-1", "A0A8V0Y5C9-1", "A0A8V1AL09-1", "A0A8V1AML5-1", "A0A8V1AP69-1", "F1NVY8-1", "R4GIV8-1", "A0A8V0ZJ49-1", "A0A8V0ZJV9-1", "A0A8V0ZL18-1", "A0A8V0ZM17-1", "A0A8V0ZSH4-1", "A0A8V0ZVX3-1", "A0A8V0ZW26-1", "A0A8V1A0Z6-1", "A0A8V0ZZH3-1", "A0A8V1A052-1", "A0A8V1A0X2-1", "A0A8V1A1I4-1", "A0A8V1A2W7-1", "A0A8V1A5P4-1", "A0A8V1A7T1-1", "A0A8V0XTY5-1", "A0A8V0Y5B5-1", "A0A8V0YL05-1", "A0A8V0Z082-1", "A0A8V0ZS27-1", "A0A8V1A9M0-1", "E1BZ35-1", "E1C3Q9-1", "F1NC08-1", "F1P2G0-1", "A0A8V0YY10-1", "A0A8V0YYC5-1", "A0A8V0Z1W7-1", "A0A8V0Z4C8-1", "A0A8V0Z596-1", "A0A1D5P284-1", "A0A8V0ZF21-1", "A0A3Q2U2G8-1", "A0A8V1A4H7-1", "A0A8V1A1N8-1", "A0A8V1A233-1", "A0A8V1A7P9-1", "A0A8V1ACU3-1", "A0A8V0ZSA3-1", "E1C656-1", "A0A8V0Y0Q7-1", "A0A8V0Y059-1", "A0A8V0Y5C7-1", "A0A8V0YCS7-1", "A0A8V0YDQ1-1", "A0A8V0YFD9-1", "A0A8V0YGF4-1", "A0A8V0YJK8-1", "A0A8V0YLY7-1", "A0A1D5NVE2-1", "A0A8V0ZKK3-1", "A0A8V0ZKQ3-1" ], "evidence": [ { "id": "R-GGA-983156", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983156" } ] }, { "id": "R-GGA-983157", "name": "Interaction of E3 with substrate and E2-Ub complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0X324-1", "A0A8V0XEM6-1", "A0A8V0XJC4-1", "A0A8V0XQR1-1", "A0A8V1AC19-1", "A0A8V1AC55-1", "A0A8V1AKB8-1", "A0A8V1ALH0-1", "F1NL19-1", "F1NRC6-1", "F1NTZ8-1", "A0A8V0YHL7-1", "A0A8V0YPW4-1", "A0A8V0YRM6-1", "A0A8V0YV22-1", "A0A8V0YVP3-1", "A0A8V0Z2L5-1", "F1NL77-1", "E1C982-1", "A0A3Q2UC96-1", "Q5ZKX6-1", "Z4YJC3-1", "A0A8V0XQU7-1", "A0A8V0Y5C9-1", "A0A8V1AL09-1", "A0A8V1AML5-1", "A0A8V1AP69-1", "F1NVY8-1", "R4GIV8-1", "A0A8V0ZJ49-1", "A0A8V0ZJV9-1", "A0A8V0ZL18-1", "A0A8V0ZM17-1", "A0A8V0ZSH4-1", "A0A8V0ZVX3-1", "A0A8V0ZW26-1", "A0A8V1A0Z6-1", "A0A8V0ZZH3-1", "A0A8V1A052-1", "A0A8V1A0X2-1", "A0A8V1A1I4-1", "A0A8V1A2W7-1", "A0A8V1A5P4-1", "A0A8V1A7T1-1", "A0A8V0XTY5-1", "A0A8V0Y5B5-1", "A0A8V0YL05-1", "A0A8V0Z082-1", "A0A8V0ZS27-1", "A0A8V1A9M0-1", "E1BZ35-1", "E1C3Q9-1", "F1NC08-1", "F1P2G0-1", "A0A8V0YY10-1", "A0A8V0YYC5-1", "A0A8V0Z1W7-1", "A0A8V0Z4C8-1", "A0A8V0Z596-1", "A0A1D5P284-1", "A0A8V0ZF21-1", "A0A3Q2U2G8-1", "A0A8V1A4H7-1", "A0A8V1A1N8-1", "A0A8V1A233-1", "A0A8V1A7P9-1", "A0A8V1ACU3-1", "A0A8V0ZSA3-1", "E1C656-1", "A0A8V0Y0Q7-1", "A0A8V0Y059-1", "A0A8V0Y5C7-1", "A0A8V0YCS7-1", "A0A8V0YDQ1-1", "A0A8V0YFD9-1", "A0A8V0YGF4-1", "A0A8V0YJK8-1", "A0A8V0YLY7-1", "A0A1D5NVE2-1", "A0A8V0ZKK3-1", "A0A8V0ZKQ3-1" ], "evidence": [ { "id": "R-GGA-983157", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983157" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5NVE2", "gene_name": "UBE2Q1", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A1D5NVE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVE2" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A1D5NVE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVE2" } ] } ] }, { "uniprot_ac": "A0A1D5P284", "gene_name": "UBR2", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A1D5P284", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P284" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A1D5P284", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P284" } ] } ] }, { "uniprot_ac": "A0A3Q2U2G8", "gene_name": "TRIM9", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A3Q2U2G8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U2G8" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A3Q2U2G8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U2G8" } ] } ] }, { "uniprot_ac": "A0A3Q2UC96", "gene_name": "NEDD4L", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A3Q2UC96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UC96" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A3Q2UC96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UC96" } ] } ] }, { "uniprot_ac": "A0A8V0X324", "gene_name": "UBE2E1", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0X324", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X324" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0X324", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X324" } ] } ] }, { "uniprot_ac": "A0A8V0XEM6", "gene_name": "HERC2", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0XEM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEM6" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0XEM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEM6" } ] } ] }, { "uniprot_ac": "A0A8V0XJC4", "gene_name": "UBE3D", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0XJC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJC4" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0XJC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJC4" } ] } ] }, { "uniprot_ac": "A0A8V0XNP1", "gene_name": "UBA6", "activity": [ { "ec_number": "6.2.1.45", "activity": "ATP + ubiquitin + [E1 ubiquitin-activating enzyme]-L-cysteine = AMP + diphosphate + S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0XNP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNP1" } ] }, { "ec_number": "6.2.1.45", "activity": "", "evidence": [ { "id": "A0A8V0XNP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNP1" } ] } ] }, { "uniprot_ac": "A0A8V0XQR1", "gene_name": "UBE2H", "activity": [ { "ec_number": "2.3.2.24", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E1 ubiquitin-activating enzyme]-L-cysteine + N(6)-monoubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0XQR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQR1" } ] }, { "ec_number": "2.3.2.24", "activity": "", "evidence": [ { "id": "A0A8V0XQR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQR1" } ] } ] }, { "uniprot_ac": "A0A8V0XQU7", "gene_name": "RNF6", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0XQU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQU7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0XQU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQU7" } ] } ] }, { "uniprot_ac": "A0A8V0XTY5", "gene_name": "SH3RF1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0XTY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XTY5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0XTY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XTY5" } ] } ] }, { "uniprot_ac": "A0A8V0Y059", "gene_name": "UBE2D1", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0Y059", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y059" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0Y059", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y059" } ] } ] }, { "uniprot_ac": "A0A8V0Y0Q7", "gene_name": "RNF144B", "activity": [ { "ec_number": "2.3.2.31", "activity": "[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.", "evidence": [ { "id": "A0A8V0Y0Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y0Q7" } ] }, { "ec_number": "2.3.2.31", "activity": "", "evidence": [ { "id": "A0A8V0Y0Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y0Q7" } ] } ] }, { "uniprot_ac": "A0A8V0Y5B5", "gene_name": "LTN1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Y5B5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5B5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0Y5B5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5B5" } ] } ] }, { "uniprot_ac": "A0A8V0Y5C7", "gene_name": "CBLL1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Y5C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5C7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0Y5C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5C7" } ] } ] }, { "uniprot_ac": "A0A8V0Y5C9", "gene_name": "HERC3", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Y5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5C9" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0Y5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5C9" } ] } ] }, { "uniprot_ac": "A0A8V0YCS7", "gene_name": "RNF19A", "activity": [ { "ec_number": "2.3.2.31", "activity": "[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.", "evidence": [ { "id": "A0A8V0YCS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCS7" } ] }, { "ec_number": "2.3.2.31", "activity": "", "evidence": [ { "id": "A0A8V0YCS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCS7" } ] } ] }, { "uniprot_ac": "A0A8V0YDQ1", "gene_name": "WWP1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YDQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDQ1" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0YDQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDQ1" } ] } ] }, { "uniprot_ac": "A0A8V0YFD9", "gene_name": "UBE2D2", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0YFD9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFD9" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0YFD9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFD9" } ] } ] }, { "uniprot_ac": "A0A8V0YGF4", "gene_name": "MYLIP", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YGF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGF4" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YGF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGF4" } ] } ] }, { "uniprot_ac": "A0A8V0YHL7", "gene_name": "RNF114", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YHL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHL7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YHL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHL7" } ] } ] }, { "uniprot_ac": "A0A8V0YJK8", "gene_name": "RNF14", "activity": [ { "ec_number": "2.3.2.31", "activity": "[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.", "evidence": [ { "id": "A0A8V0YJK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJK8" } ] }, { "ec_number": "2.3.2.31", "activity": "", "evidence": [ { "id": "A0A8V0YJK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJK8" } ] } ] }, { "uniprot_ac": "A0A8V0YL05", "gene_name": "UBE3A", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YL05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL05" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0YL05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL05" } ] } ] }, { "uniprot_ac": "A0A8V0YLY7", "gene_name": "MKRN4P", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLY7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLY7" } ] } ] }, { "uniprot_ac": "A0A8V0YPW4", "gene_name": "UBE2J2", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0YPW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPW4" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0YPW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPW4" } ] } ] }, { "uniprot_ac": "A0A8V0YRM6", "gene_name": "RNF130", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YRM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRM6" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YRM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRM6" } ] } ] }, { "uniprot_ac": "A0A8V0YV22", "gene_name": "RNF4", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YV22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YV22" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YV22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YV22" } ] } ] }, { "uniprot_ac": "A0A8V0YVP3", "gene_name": "RBBP6", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YVP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVP3" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YVP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVP3" } ] } ] }, { "uniprot_ac": "A0A8V0YY10", "gene_name": "UBE2D3", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0YY10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YY10" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0YY10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YY10" } ] } ] }, { "uniprot_ac": "A0A8V0YYC5", "gene_name": "ZNRF2", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YYC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYC5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YYC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYC5" } ] } ] }, { "uniprot_ac": "A0A8V0Z082", "gene_name": "UBE2B", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0Z082", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z082" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0Z082", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z082" } ] } ] }, { "uniprot_ac": "A0A8V0Z1W7", "gene_name": "UBE2K", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0Z1W7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1W7" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0Z1W7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1W7" } ] } ] }, { "uniprot_ac": "A0A8V0Z2L5", "gene_name": "TRIM63", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Z2L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2L5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0Z2L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2L5" } ] } ] }, { "uniprot_ac": "A0A8V0Z4C8", "gene_name": "MGRN1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Z4C8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4C8" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0Z4C8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4C8" } ] } ] }, { "uniprot_ac": "A0A8V0Z596", "gene_name": "STUB1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Z596", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z596" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0Z596", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z596" } ] } ] }, { "uniprot_ac": "A0A8V0ZBK2", "gene_name": "UBA3", "activity": [ { "ec_number": "6.2.1.64", "activity": "ATP + [NEDD8 protein] + [E1 NEDD8-activating enzyme]-L-cysteine = AMP + diphosphate + [E1 NEDD8-activating enzyme]-S-[NEDD8 protein]-yl-L-cysteine.", "evidence": [ { "id": "A0A8V0ZBK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBK2" } ] }, { "ec_number": "6.2.1.64", "activity": "", "evidence": [ { "id": "A0A8V0ZBK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBK2" } ] } ] }, { "uniprot_ac": "A0A8V0ZF21", "gene_name": "DTX3L", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZF21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF21" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZF21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF21" } ] } ] }, { "uniprot_ac": "A0A8V0ZJ49", "gene_name": "SMURF1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZJ49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ49" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZJ49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ49" } ] } ] }, { "uniprot_ac": "A0A8V0ZJV9", "gene_name": "MIB2", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZJV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJV9" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZJV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJV9" } ] } ] }, { "uniprot_ac": "A0A8V0ZKK3", "gene_name": "UBE3B", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKK3" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKK3" } ] } ] }, { "uniprot_ac": "A0A8V0ZKQ3", "gene_name": "RNF25", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZKQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKQ3" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZKQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKQ3" } ] } ] }, { "uniprot_ac": "A0A8V0ZL18", "gene_name": "HECTD2", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZL18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL18" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZL18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL18" } ] } ] }, { "uniprot_ac": "A0A8V0ZM17", "gene_name": "UBR1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZM17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM17" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZM17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM17" } ] } ] }, { "uniprot_ac": "A0A8V0ZS27", "gene_name": "TRIP12", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZS27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS27" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZS27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS27" } ] } ] }, { "uniprot_ac": "A0A8V0ZSA3", "gene_name": "HERC4", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZSA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSA3" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZSA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSA3" } ] } ] }, { "uniprot_ac": "A0A8V0ZSH4", "gene_name": "RNF111", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZSH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSH4" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZSH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSH4" } ] } ] }, { "uniprot_ac": "A0A8V0ZVX3", "gene_name": "NEDD4", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZVX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVX3" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZVX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVX3" } ] } ] }, { "uniprot_ac": "A0A8V0ZW26", "gene_name": "ZNRF1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZW26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZW26" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZW26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZW26" } ] } ] }, { "uniprot_ac": "A0A8V0ZZH3", "gene_name": "ITCH", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZZH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZH3" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZZH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZH3" } ] } ] }, { "uniprot_ac": "A0A8V1A052", "gene_name": "UBE2E3", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V1A052", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A052" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V1A052", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A052" } ] } ] }, { "uniprot_ac": "A0A8V1A0X2", "gene_name": "UBE3C", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A0X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0X2" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V1A0X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0X2" } ] } ] }, { "uniprot_ac": "A0A8V1A0Z6", "gene_name": "UBE4A", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A0Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Z6" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1A0Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Z6" } ] } ] }, { "uniprot_ac": "A0A8V1A1I4", "gene_name": "UBE2Z", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V1A1I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1I4" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V1A1I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1I4" } ] } ] }, { "uniprot_ac": "A0A8V1A1N8", "gene_name": "HERC1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A1N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1N8" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V1A1N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1N8" } ] } ] }, { "uniprot_ac": "A0A8V1A233", "gene_name": "RNF220", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A233", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A233" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1A233", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A233" } ] } ] }, { "uniprot_ac": "A0A8V1A2W7", "gene_name": "RNF41", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A2W7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2W7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1A2W7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2W7" } ] } ] }, { "uniprot_ac": "A0A8V1A4H7", "gene_name": "UBE2L3", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V1A4H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4H7" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V1A4H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4H7" } ] } ] }, { "uniprot_ac": "A0A8V1A5P4", "gene_name": "UBE2G2", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V1A5P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5P4" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V1A5P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5P4" } ] } ] }, { "uniprot_ac": "A0A8V1A7P9", "gene_name": "DCAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] } ] }, { "uniprot_ac": "A0A8V1A7T1", "gene_name": "RNF123", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A7T1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7T1" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1A7T1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7T1" } ] } ] }, { "uniprot_ac": "A0A8V1A9M0", "gene_name": "RNF34", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A9M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9M0" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1A9M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9M0" } ] } ] }, { "uniprot_ac": "A0A8V1AC19", "gene_name": "UBA7", "activity": [ { "ec_number": "6.2.1.45", "activity": "ATP + ubiquitin + [E1 ubiquitin-activating enzyme]-L-cysteine = AMP + diphosphate + S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V1AC19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC19" } ] }, { "ec_number": "6.2.1.45", "activity": "", "evidence": [ { "id": "A0A8V1AC19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC19" } ] } ] }, { "uniprot_ac": "A0A8V1AC55", "gene_name": "SMURF2", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1AC55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC55" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V1AC55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC55" } ] } ] }, { "uniprot_ac": "A0A8V1ACU3", "gene_name": "UBE2O", "activity": [ { "ec_number": "2.3.2.24", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E1 ubiquitin-activating enzyme]-L-cysteine + N(6)-monoubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1ACU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACU3" } ] }, { "ec_number": "2.3.2.24", "activity": "", "evidence": [ { "id": "A0A8V1ACU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACU3" } ] } ] }, { "uniprot_ac": "A0A8V1AKB8", "gene_name": "TRIM32", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1AKB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKB8" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1AKB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKB8" } ] } ] }, { "uniprot_ac": "A0A8V1AL09", "gene_name": "TRIM37", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1AL09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL09" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1AL09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL09" } ] } ] }, { "uniprot_ac": "A0A8V1ALH0", "gene_name": "RNF213", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1ALH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALH0" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1ALH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALH0" } ] } ] }, { "uniprot_ac": "A0A8V1AML5", "gene_name": "TRIM50", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1AML5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AML5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1AML5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AML5" } ] } ] }, { "uniprot_ac": "A0A8V1AP69", "gene_name": "TRIM58", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1AP69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP69" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1AP69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP69" } ] } ] }, { "uniprot_ac": "E1BZ35", "gene_name": "RNF182", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1BZ35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BZ35" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "E1BZ35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BZ35" } ] } ] }, { "uniprot_ac": "E1C3Q9", "gene_name": "SIAH2", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1C3Q9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C3Q9" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "E1C3Q9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C3Q9" } ] } ] }, { "uniprot_ac": "E1C656", "gene_name": "HACE1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1C656", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C656" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "E1C656", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C656" } ] } ] }, { "uniprot_ac": "E1C982", "gene_name": "AREL1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1C982", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C982" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "E1C982", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C982" } ] } ] }, { "uniprot_ac": "F1NC08", "gene_name": "RNF138", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1NC08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NC08" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "F1NC08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NC08" } ] } ] }, { "uniprot_ac": "F1NL19", "gene_name": "CDC34", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "F1NL19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NL19" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "F1NL19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NL19" } ] } ] }, { "uniprot_ac": "F1NL77", "gene_name": "CBLB", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1NL77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NL77" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "F1NL77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NL77" } ] } ] }, { "uniprot_ac": "F1NRC6", "gene_name": "RLIM", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1NRC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NRC6" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "F1NRC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NRC6" } ] } ] }, { "uniprot_ac": "F1NTZ8", "gene_name": "HECW2", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1NTZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NTZ8" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "F1NTZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NTZ8" } ] } ] }, { "uniprot_ac": "F1NVY8", "gene_name": "LNX1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1NVY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVY8" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "F1NVY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVY8" } ] } ] }, { "uniprot_ac": "F1P2G0", "gene_name": "SIAH1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1P2G0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P2G0" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "F1P2G0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P2G0" } ] } ] }, { "uniprot_ac": "Q5ZKX6", "gene_name": "UBE2F", "activity": [ { "ec_number": "2.3.2.34", "activity": "[E1 NEDD8-activating enzyme]-S-[NEDD8 protein]-yl-L-cysteine + [E2 NEDD8-conjugating enzyme]-L-cysteine = [E1 NEDD8-activating enzyme]-L-cysteine + [E2 NEDD8-conjugating enzyme]-S-[NEDD8-protein]-yl-L-cysteine.", "evidence": [ { "id": "Q5ZKX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKX6" } ] }, { "ec_number": "2.3.2.34", "activity": "", "evidence": [ { "id": "Q5ZKX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKX6" } ] } ] }, { "uniprot_ac": "R4GIV8", "gene_name": "UBE2R2", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "R4GIV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GIV8" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "R4GIV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GIV8" } ] } ] }, { "uniprot_ac": "Z4YJC3", "gene_name": "TRIM71", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor 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"S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E1 ubiquitin-activating enzyme]-L-cysteine + N(6)-monoubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "2.3.2.24", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.3.2.24" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 35 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 321, "end_pos": 323 }, { "start_pos": 799, "end_pos": 801 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { 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Binds polymeric IgA and IgM at the basolateral surface of epithelial cells. The complex is then transported across the cell to be secreted at the apical surface. During this process, a cleavage occurs that separates the extracellular (known as the secretory component) from the transmembrane segment.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACV0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACV0#function" }, { "database": "UniProtKB", "id": "ARBA00049599", "url": "https://www.uniprot.org/uniprotkb/ARBA00049599#function" } ] }, { "annotation": "Through its N-linked glycans ensures anchoring of secretory IgA (sIgA) molecules to mucus lining the epithelial surface to neutralize extracellular pathogens. On its own (free form) may act as a non-specific microbial scavenger to prevent pathogen interaction with epithelial cells.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACV0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACV0#function" }, { "database": "UniProtKB", "id": "ARBA00049604", "url": "https://www.uniprot.org/uniprotkb/ARBA00049604#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACV0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACV0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PIGR", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACV0", "locus": { "chromosome": "26", "start_pos": 2615692, "end_pos": 2626239, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027141", "url": "https://www.ensembl.org/id/ENSGALG00010027141" } ] } } ], "crossref": [ { "id": "A0A8V1ACV0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1ACV0", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd05716", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05716", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013106", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013106", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050671", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050671", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ACV0", "url": "https://www.orthodb.org/?gene=A0A8V1ACV0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11860", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11860", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11860:SF82", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11860:SF82", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07686", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07686", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-6798695", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1ACV0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACV0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ACV0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACV0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVCRSNLTWNARRMTLLAFILLLSFLPAESAKSRYPPKTSLNPVFGPQQVYGLIDGSVSIKCFYPPTTVNRHDRKYWCRESSRSCLTVVSTSGYRARGYQGRVTIVDFPEQGIMLVNISQLTLADQGTYQCGIGLNGKGLSNRVSLDISEGPNIPEEAELFYVELQGSVSMACDFGEDYASTRKFLCKMEKSGCRNIIDTYGKIDSDFQGRILLSNENTEGAFSVMITQVDWEDAGLYLCGVGSYGEYGETKELDLHVYEGTKAAQGKHTIFGVKGSSATIDCHYDPTKNYSLKYLCKWRTTGCARIIDNTGFLPGPYEGRVAMFDNPKNGTFSIVLNQLSSRDEGFYWCMTDDHRERRTSKELKIVEGECGLTGKEEVQAEVGSRVDLTCSYPCKYYSYEKYWCKWSRDGCTPLTSSDQSHPGLDVSCDTANKTLILSLDPVTVEDQGWYWCGVKHNGHYGETMAVSLQVDGGKAANISPELLDLEASNAAAAPDEAVPQGRANSDAGVQRAAASESSEQSSGSSTLALILGPIGAALLVLAAAFAVFKYRQIRRSDLVSVGSYRTNISMSDFENAREYGANDNVCMKQSQETQLGGDEFVTTTANTESTAETKKAKRGSKEDADLAYSASLLTPSTTTQSPAGDSTAPAEAPPLWGGSV", "length": 661, "header": "tr|A0A8V1ACV0-1|A0A8V1ACV0_CHICK Isoform 1 of Polymeric immunoglobulin receptor OS=Gallus gallus OX=9031 GN=PIGR PE=1 SV=1 CANONICAL=A0A8V1ACV0-1" }, "isoforms": [ { "isoform_ac": "A0A8V1ACV0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACV0/entry#A0A8V1ACV0-1", "sequence": { "sequence": "MVCRSNLTWNARRMTLLAFILLLSFLPAESAKSRYPPKTSLNPVFGPQQVYGLIDGSVSIKCFYPPTTVNRHDRKYWCRESSRSCLTVVSTSGYRARGYQGRVTIVDFPEQGIMLVNISQLTLADQGTYQCGIGLNGKGLSNRVSLDISEGPNIPEEAELFYVELQGSVSMACDFGEDYASTRKFLCKMEKSGCRNIIDTYGKIDSDFQGRILLSNENTEGAFSVMITQVDWEDAGLYLCGVGSYGEYGETKELDLHVYEGTKAAQGKHTIFGVKGSSATIDCHYDPTKNYSLKYLCKWRTTGCARIIDNTGFLPGPYEGRVAMFDNPKNGTFSIVLNQLSSRDEGFYWCMTDDHRERRTSKELKIVEGECGLTGKEEVQAEVGSRVDLTCSYPCKYYSYEKYWCKWSRDGCTPLTSSDQSHPGLDVSCDTANKTLILSLDPVTVEDQGWYWCGVKHNGHYGETMAVSLQVDGGKAANISPELLDLEASNAAAAPDEAVPQGRANSDAGVQRAAASESSEQSSGSSTLALILGPIGAALLVLAAAFAVFKYRQIRRSDLVSVGSYRTNISMSDFENAREYGANDNVCMKQSQETQLGGDEFVTTTANTESTAETKKAKRGSKEDADLAYSASLLTPSTTTQSPAGDSTAPAEAPPLWGGSV", "length": 661, "header": "tr|A0A8V1ACV0-1|A0A8V1ACV0_CHICK Isoform 1 of Polymeric immunoglobulin receptor OS=Gallus gallus OX=9031 GN=PIGR PE=1 SV=1 CANONICAL=A0A8V1ACV0-1" }, "locus": { "chromosome": "26", "start_pos": 2626037, "end_pos": 2616092, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065802.1", "url": "https://www.ensembl.org/id/ENSGALT00010065802.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040068.1", "url": "https://www.ensembl.org/id/ENSGALP00010040068.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-6798695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798695", "resource": "Reactome", "description": "Neutrophil degranulation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor", "id": "GO:0002415", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002415", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACV0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACV0" } ], "pmid": "" }, { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACV0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACV0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "transmembrane signaling receptor activity", "id": "GO:0004888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004888", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACV0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACV0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACV0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACV0" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACV0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACV0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 117, "end_pos": 119, "annotation": "n_glycosylation_sequon" }, { "start_pos": 290, "end_pos": 292, "annotation": "n_glycosylation_sequon" }, { "start_pos": 330, "end_pos": 332, "annotation": "n_glycosylation_sequon" }, { "start_pos": 433, "end_pos": 435, "annotation": "n_glycosylation_sequon" }, { "start_pos": 478, "end_pos": 480, "annotation": "n_glycosylation_sequon" }, { "start_pos": 568, "end_pos": 570, "annotation": "n_glycosylation_sequon" }, { "start_pos": 6, "end_pos": 8, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1ACV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACV0" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 362, "end_pos": 470, "start_aa": "Lys", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 117, "end_pos": 119 }, { "start_pos": 290, "end_pos": 292 }, { "start_pos": 330, "end_pos": 332 }, { "start_pos": 433, "end_pos": 435 }, { "start_pos": 478, "end_pos": 480 }, { "start_pos": 568, "end_pos": 570 }, { "start_pos": 6, "end_pos": 8 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": 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"o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1ACX2-1", "uniprot_ac": "A0A8V1ACX2", "uniprot_id": "A0A8V1ACX2_CHICK", "mass": { "chemical_mass": 25335.0, "monoisotopic_mass": 25335.0 }, "refseq": { "ac": "XP_004950573", "name": "linker for activation of T-cells family member 2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004950573" }, "gene_names": [ { "name": "LAT2", "type": "recommended", "evidence": [ { "id": "A0A8V1ACX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACX2" } ] }, { "name": "LAT2", "type": "synonym", "evidence": [ { "id": "XP_004950573", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004950573" } ] }, { "name": "WBSCR5", "type": "synonym", "evidence": [ { "id": "XP_004950573", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004950573" } ] } ], "protein_names": [ { "name": "Linker for activation of T cells family member 2", "type": "synonym", "evidence": [ { "id": "A0A8V1ACX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACX2/entry#names_and_taxonomy" } ] }, { "name": "linker for activation of T-cells family member 2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_004950573", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004950573" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052550.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004950573.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004950573", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004950573" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACX2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACX2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LAT2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACX2", "locus": { "chromosome": "19", "start_pos": 3344690, "end_pos": 3353959, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029420", "url": "https://www.ensembl.org/id/ENSGALG00010029420" } ] } } ], "crossref": [ { "id": "A0A8V1ACX2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1ACX2", "database": "AlphaFoldDB", "categories": [] }, { "id": "417489", "url": "https://www.ncbi.nlm.nih.gov/gene/417489", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR031428", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031428", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "FMGSQTY", "url": "https://omabrowser.org/oma/group/FMGSQTY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ACX2", "url": "https://www.orthodb.org/?gene=A0A8V1ACX2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AI89", "url": "https://www.orthodb.org/?gene=A0A8V1AI89", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AM55", "url": "https://www.orthodb.org/?gene=A0A8V1AM55", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ANP3", "url": "https://www.orthodb.org/?gene=A0A8V1ANP3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15646", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15646", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15646:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15646:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15703", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15703", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-2730905", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2730905", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_004950573", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004950573", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1ACX2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACX2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ACX2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACX2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AI89", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI89", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AI89-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI89-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AM55", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM55", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AM55-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM55-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ANP3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANP3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ANP3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANP3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTWKGGQGWSWGEVTALLTAVFQAGCGWAMAQPELLWAAAGLMLLGVAVSACVRCQLYATKRGKDGSQGSRLERPQRFEVIRSCSAVTRRPERIKEPENLARKAPEELSTSCHVGFESSAEPRYQNFLTEDCLHEDAAYVEPVPLDYYSHNRFFSPPNDEDSHSYQNVIIGDPCSSELDDAEDYENSTAIEVWKVQQAKAMLYAESQDEEPDYVNTDPTIDAVVLSK", "length": 227, "header": "tr|A0A8V1ACX2-1|A0A8V1ACX2_CHICK Isoform 1 of Linker for activation of T cells family member 2 OS=Gallus gallus OX=9031 GN=LAT2 PE=4 SV=1 CANONICAL=A0A8V1ACX2-1" }, "isoforms": [ { "isoform_ac": "A0A8V1ACX2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACX2/entry#A0A8V1ACX2-1", "sequence": { "sequence": "MTWKGGQGWSWGEVTALLTAVFQAGCGWAMAQPELLWAAAGLMLLGVAVSACVRCQLYATKRGKDGSQGSRLERPQRFEVIRSCSAVTRRPERIKEPENLARKAPEELSTSCHVGFESSAEPRYQNFLTEDCLHEDAAYVEPVPLDYYSHNRFFSPPNDEDSHSYQNVIIGDPCSSELDDAEDYENSTAIEVWKVQQAKAMLYAESQDEEPDYVNTDPTIDAVVLSK", "length": 227, "header": "tr|A0A8V1ACX2-1|A0A8V1ACX2_CHICK Isoform 1 of Linker for activation of T cells family member 2 OS=Gallus gallus OX=9031 GN=LAT2 PE=4 SV=1 CANONICAL=A0A8V1ACX2-1" }, "locus": { "chromosome": "19", "start_pos": 3350902, "end_pos": 3346288, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071168.1", "url": "https://www.ensembl.org/id/ENSGALT00010071168.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043859.1", "url": "https://www.ensembl.org/id/ENSGALP00010043859.1" } ] } }, { "isoform_ac": "A0A8V1AI89-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACX2/entry#A0A8V1AI89-1", "sequence": { "sequence": "MLRPAAAAHGHRMLSSKAGCGWAMAQPELLWAAAGLMLLGVAVSACVRCQLYATKRGKDGSQGSRLERPQRFEVIRSCSAVTRRPERIKEPENLARKAPEELSTSCHVGFEDCLHEDAAYVEPVPLDYYSHNRFFSPPNDEDSHSYQNVIIGDPCSSELDDAEDYENSTAIEVWKVQQAKAMLYAESQDEEPDYVNTDPTIDAVVLSK", "length": 208, "header": "tr|A0A8V1AI89-1|A0A8V1ACX2_CHICK Computationally mapped isoform of Linker for activation of T cells family member 2 OS=Gallus gallus OX=9031 GN=LAT2 PE=4 SV=1 CANONICAL=A0A8V1ACX2-1" }, "locus": { "chromosome": "19", "start_pos": 3353411, "end_pos": 3346288, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071170.1", "url": "https://www.ensembl.org/id/ENSGALT00010071170.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043861.1", "url": "https://www.ensembl.org/id/ENSGALP00010043861.1" } ] } }, { "isoform_ac": "A0A8V1AM55-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACX2/entry#A0A8V1AM55-1", "sequence": { "sequence": "RSPEEPSPAPTRGDGTEGDGRLRLRSSVLDAAPCCRCSRPSYAELQATKRGKDGSQGSRLERPQRFEVIRSCSAVTRRPERIKEPENLARKAPEELSTSCHVGFESSAEPRYQNFLTEDCLHEDAAYVEPVPLDYYSHNRFFSPPNDEDSHSYQNVIIGDPCSSELDDAEDYENSTAIEVWKVQQAKAMLYAESQDEEPDYVNTDPTIDAVVLSK", "length": 215, "header": "tr|A0A8V1AM55-1|A0A8V1ACX2_CHICK Computationally mapped isoform of Linker for activation of T cells family member 2 OS=Gallus gallus OX=9031 GN=LAT2 PE=4 SV=1 CANONICAL=A0A8V1ACX2-1" }, "locus": { "chromosome": "19", "start_pos": 3353660, "end_pos": 3346288, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071171.1", "url": "https://www.ensembl.org/id/ENSGALT00010071171.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043862.1", "url": "https://www.ensembl.org/id/ENSGALP00010043862.1" } ] } }, { "isoform_ac": "A0A8V1ANP3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACX2/entry#A0A8V1ANP3-1", "sequence": { "sequence": "MLRPAAAAHGHRMLSSKAGCGWAMAQPELLWAAAGLMLLGVAVSACVRCQLYATKRGKDGSQGSRLERPQRFEVIRSCSAVTRRPERIKEPENLARKAPEELSTSCHVGFESSAEPRYQNFLTEDCLHEDAAYVEPVPLDYYSHNRFFSPPNDEDSHSYQNVIIGDPCSSELDDAEDYENSTAIEVWKVQQAKAMLYAESQDEEPDYVNTDPTIDAVVLSK", "length": 221, "header": "tr|A0A8V1ANP3-1|A0A8V1ACX2_CHICK Computationally mapped isoform of Linker for activation of T cells family member 2 OS=Gallus gallus OX=9031 GN=LAT2 PE=4 SV=1 CANONICAL=A0A8V1ACX2-1" }, "locus": { "chromosome": "19", "start_pos": 3353411, "end_pos": 3346288, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071169.1", "url": "https://www.ensembl.org/id/ENSGALT00010071169.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043860.1", "url": "https://www.ensembl.org/id/ENSGALP00010043860.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-2730905", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2730905", "resource": "Reactome", "description": "Role of LAT2/NTAL/LAB on calcium mobilization" } ], "orthologs": [ { "uniprot_canonical_ac": "Q8CGL2-1", "protein_name": "Linker for activation of T-cells family member 2", "gene_name": "Lat2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNAELELLWPLSGLLLLLLLGTTAWLCVQCSRPGVKRNEKIYEQRNQQENEQSVASSQTYSLARPVRTGLQMDAASNKSFERKNKLLFSHLEGPESPRYQNFYKGSRRESDAAYVDPIPTDYYNWGCFQKPPEDNDSNSYENVLICKPSTPESGTEESEDYQNSVSILQWRESKRTMGARTSPSGSPDEEPDYVNGDVATTEKI", "length": 204 }, "evidence": [ { "id": "A0A8V1ACX2", "url": "https://omabrowser.org/oma/group/A0A8V1ACX2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9GZY6-1", "protein_name": "Linker for activation of T-cells family member 2", "gene_name": "LAT2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSSGTELLWPGAALLVLLGVAASLCVRCSRPGAKRSEKIYQQRSLREDQQSFTGSRTYSLVGQAWPGPLADMAPTRKDKLLQFYPSLEDPASSRYQNFSKGSRHGSEEAYIDPIAMEYYNWGRFSKPPEDDDANSYENVLICKQKTTETGAQQEGIGGLCRGDLSLSLALKTGPTSGLCPSASPEEDEESEDYQNSASIHQWRESRKVMGQLQREASPGPVGSPDEEDGEPDYVNGEVAATEA", "length": 243 }, "evidence": [ { "id": "A0A8V1ACX2", "url": "https://omabrowser.org/oma/group/A0A8V1ACX2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9JHL0-1", "protein_name": "Linker for activation of T-cells family member 2", "gene_name": "Lat2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAELELLWPVSGLLLLLLGATAWLCVHCSRPGVKRNEKIYEQRNRQENAQSSAAAQTYSLARQVWPGPQMDTAPNKSFERKNKMLFSHLEGPESPRYQNFYKGSNQEPDAAYVDPIPTNYYNWGCFQKPSEDDDSNSYENVLVCKPSTPESGVEDFEDYQNSVSIHQWRESKRTMGAPMSLSGSPDEEPDYVNGDVAAAENI", "length": 203 }, "evidence": [ { "id": "A0A8V1ACX2", "url": "https://omabrowser.org/oma/group/A0A8V1ACX2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACX2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACX2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "calcium-mediated signaling", "id": "GO:0019722", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019722", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACX2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACX2" } ], "pmid": "" }, { "name": "B cell activation", "id": "GO:0042113", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042113", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACX2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACX2" } ], "pmid": "" }, { "name": "B cell receptor signaling pathway", "id": "GO:0050853", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050853", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACX2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACX2" } ], "pmid": "" }, { "name": "immune response-regulating signaling pathway", "id": "GO:0002764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002764", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACX2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACX2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 186, "end_pos": 188, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 186, "end_pos": 188 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1ACY4-1", "uniprot_ac": "A0A8V1ACY4", "uniprot_id": "A0A8V1ACY4_CHICK", "mass": { "chemical_mass": 56407.0, "monoisotopic_mass": 56407.0 }, "refseq": { "ac": "NP_001376619", "name": "sphingosine-1-phosphate transporter SPNS2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376619" }, "gene_names": [ { "name": "SPNS2", "type": "recommended", "evidence": [ { "id": "A0A8V1ACY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACY4" } ] }, { "name": "SPNS2", "type": "synonym", "evidence": [ { "id": "NP_001376619", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376619" } ] } ], "protein_names": [ { "name": "Spinster homolog 2", "type": "synonym", "evidence": [ { "id": "A0A8V1ACY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACY4/entry#names_and_taxonomy" } ] }, { "name": "sphingosine-1-phosphate transporter SPNS2", "type": "synonym", "evidence": [ { "id": "NP_001376619", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376619" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## inferred exon combination :: based on alignments, homology ##RefSeq-Attributes-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000323.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001376619", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376619" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACY4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACY4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SPNS2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACY4", "locus": { "chromosome": "19", "start_pos": 3425410, "end_pos": 3551160, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029425", "url": "https://www.ensembl.org/id/ENSGALG00010029425" } ] } } ], "crossref": [ { "id": "A0A8V1ACY4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1ACY4", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd17328", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17328", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "417492", "url": "https://www.ncbi.nlm.nih.gov/gene/417492", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011701", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011701", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020846", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020846", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036259", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036259", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR23505", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23505", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23505:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23505:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07690", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07690", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-1660661", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1660661", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001376619", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376619", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1ACY4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACY4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ACY4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACY4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AIA3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIA3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AIA3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIA3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMCLESDGSSGSSPGCGGRLRAGDEEEEEDGERGCCGRGAEGEVQTLSGRMNPPAVGKRPERPIARHKAPSLGRARVAAAGILSVGNVLNYLDRYTVAGVLLDIQQHFGVKDSGAGLLQTVFICSFMVAAPIFGYLGDRFNRKIILSCGIFFWSAVTFSSSFITEQYFWLLVLSRGLVGIGEASYSTIAPTIIGDLFNRNTRTLMLSVFYFAIPLGSGLGYITGSSVKQVAGDWHWALRVSPLLGMITGTLILIFVPAAKRGNVEQLGGQLKARTSWLRDMKALIRNRSYVFSSLATSAVSFATGALGMWIPLYLHRAQVVQKTAETCISQPCGTKDSLIFGAITCFTGFLGVITGAGATKWCRLKTQRADPLVCAVGMLGSAIFICLIFVAAKSSIVGAYICIFIGETLLFSNWAITADILMYVVIPTRRATAVALQSFTSHLLGDAGSPYLIGFISDLIRQSTKESPLWEFLSLGYALMLCPFVVVLGGMFFLATALFFLSDRAKAEQQVNQLVMPPASVKV", "length": 524, "header": "tr|A0A8V1ACY4-1|A0A8V1ACY4_CHICK Isoform 1 of Spinster homolog 2 OS=Gallus gallus OX=9031 GN=SPNS2 PE=3 SV=1 CANONICAL=A0A8V1ACY4-1" }, "isoforms": [ { "isoform_ac": "A0A8V1ACY4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACY4/entry#A0A8V1ACY4-1", "sequence": { "sequence": "MMCLESDGSSGSSPGCGGRLRAGDEEEEEDGERGCCGRGAEGEVQTLSGRMNPPAVGKRPERPIARHKAPSLGRARVAAAGILSVGNVLNYLDRYTVAGVLLDIQQHFGVKDSGAGLLQTVFICSFMVAAPIFGYLGDRFNRKIILSCGIFFWSAVTFSSSFITEQYFWLLVLSRGLVGIGEASYSTIAPTIIGDLFNRNTRTLMLSVFYFAIPLGSGLGYITGSSVKQVAGDWHWALRVSPLLGMITGTLILIFVPAAKRGNVEQLGGQLKARTSWLRDMKALIRNRSYVFSSLATSAVSFATGALGMWIPLYLHRAQVVQKTAETCISQPCGTKDSLIFGAITCFTGFLGVITGAGATKWCRLKTQRADPLVCAVGMLGSAIFICLIFVAAKSSIVGAYICIFIGETLLFSNWAITADILMYVVIPTRRATAVALQSFTSHLLGDAGSPYLIGFISDLIRQSTKESPLWEFLSLGYALMLCPFVVVLGGMFFLATALFFLSDRAKAEQQVNQLVMPPASVKV", "length": 524, "header": "tr|A0A8V1ACY4-1|A0A8V1ACY4_CHICK Isoform 1 of Spinster homolog 2 OS=Gallus gallus OX=9031 GN=SPNS2 PE=3 SV=1 CANONICAL=A0A8V1ACY4-1" }, "locus": { "chromosome": "19", "start_pos": 3551032, "end_pos": 3431503, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071183.1", "url": "https://www.ensembl.org/id/ENSGALT00010071183.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043874.1", "url": "https://www.ensembl.org/id/ENSGALP00010043874.1" } ] } }, { "isoform_ac": "A0A8V1AIA3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACY4/entry#A0A8V1AIA3-1", "sequence": { "sequence": "MMCLESDGSSGSSPGCGGRLRAGDEEEEEDGERGCCGRGAEGEVQTLSGRMNPPAVGKRPERPIARHKAPSLGRARVAAAGILSVGNVLNYLDRYTVAGVLLDIQQHFGVKDSGAGLLQTVFICSFMVAAPIFGYLGDRFNRKIILSCGIFFWSAVTFSSSFITEQYFWLLVLSRGLVGIGEASYSTIAPTIIGDLFNRNTRTLMLSVFYFAIPLGSGLGYITGSSVKQVAGDWHWALRVSPLLGMITGTLILIFVPAAKRGNVEQLGGQLKARTSWLRDMKALIRNRSYVFSSLATSAVSFATGALGMWIPLYLHRAQVVQKTAETCISQPCGTKDSLIFGAITCFTGFLGVITGAGATKWCRLKTQRADPLVCAVGMLGSAIFICLIFVAAKSSIVGAYICIFIGETLLFSNWAITADILMYVVIPTRRATAVALQSFTSHLLGDAGSPYLIGFEGCFSWPQPSSSSVTEPKLNNIMKPIRTTSRLATTVIQKTLPHDIHTPGGEPTCDATSLCESLRC", "length": 521, "header": "tr|A0A8V1AIA3-1|A0A8V1ACY4_CHICK Computationally mapped isoform of Spinster homolog 2 OS=Gallus gallus OX=9031 GN=SPNS2 PE=3 SV=1 CANONICAL=A0A8V1ACY4-1" }, "locus": { "chromosome": "19", "start_pos": 3551032, "end_pos": 3429655, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071185.1", "url": "https://www.ensembl.org/id/ENSGALT00010071185.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043876.1", "url": "https://www.ensembl.org/id/ENSGALP00010043876.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-1660661", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1660661", "resource": "Reactome", "description": "Sphingolipid de novo biosynthesis" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "sphingosine-1-phosphate receptor signaling pathway", "id": "GO:0003376", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003376", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACY4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACY4" } ], "pmid": "" }, { "name": "lipid transport", "id": "GO:0006869", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006869", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACY4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACY4" } ], "pmid": "" }, { "name": "sensory perception of sound", "id": "GO:0007605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007605", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACY4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACY4" } ], "pmid": "" }, { "name": "regulation of T cell migration", "id": "GO:2000404", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000404", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACY4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACY4" } ], "pmid": "" }, { "name": "regulation of humoral immune response", "id": "GO:0002920", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002920", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACY4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACY4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACY4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACY4" } ], "pmid": "" }, { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACY4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACY4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "transmembrane transporter activity", "id": "GO:0022857", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022857", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACY4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACY4" } ], "pmid": "" }, { "name": "sphingolipid transporter activity", "id": "GO:0046624", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046624", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACY4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACY4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 287, "end_pos": 289, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1ACY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACY4" }, { "id": "PS50850", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50850" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Major facilitator superfamily (MFS) profile", "eco_id": "ECO_0000259", "start_pos": 79, "end_pos": 507, "start_aa": "Ala", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 287, "end_pos": 289 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1ACZ0-1", "uniprot_ac": "A0A8V1ACZ0", "uniprot_id": "A0A8V1ACZ0_CHICK", "mass": { "chemical_mass": 39475.0, "monoisotopic_mass": 39475.0 }, "refseq": {}, "gene_names": [ { "name": "CD55", "type": "recommended", "evidence": [ { "id": "A0A8V1ACZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACZ0" } ] } ], "protein_names": [ { "name": "CD55 molecule (Cromer blood group)", "type": "synonym", "evidence": [ { "id": "A0A8V1ACZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACZ0/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACZ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACZ0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CD55", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACZ0", "locus": {} } ], "crossref": [ { "id": "A0A8V1ACZ0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1ACZ0", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00033", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00033", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000436", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000436", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035976", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035976", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050350", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050350", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ACZ0", "url": "https://www.orthodb.org/?gene=A0A8V1ACZ0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19325", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19325", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19325:SF571", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19325:SF571", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00084", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00084", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1ACZ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACZ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ACZ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACZ0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKTDPRCPEPGGGSAPFVVRRLRAGRGRGRAGPEEFPRCPSATMGSAPYRSLLPLLPLLLSPLSLLPAVCGDCGPLPNISRAEPPEDVRHQDSFPVGSKVTYRCLQNFSKIPSRLDTIVCFNNSLWSNLQEFCDRSCQSPPQVPFAKLSAEDEMKNFYAVGTTVRYNCSRGYENSSAVLPSSTCQENSTWSEVPELCRKRSCGPPANPEHGKVLVTDHLYRARAEVVCDKGYTPSKKRPFITCFAEEDEVAWTPLPKCLASPSVSDTTAVTDSTTHLEEKASENNYILPLILVPSIIGLTSQIQGMKSRIHPKRSTGLRGVQGQQQPNPDSARILQWRNSVLRSRRFKLASDSAPSPFA", "length": 359, "header": "tr|A0A8V1ACZ0-1|A0A8V1ACZ0_CHICK Isoform 1 of CD55 molecule (Cromer blood group) OS=Gallus gallus OX=9031 GN=CD55 PE=4 SV=1 CANONICAL=A0A8V1ACZ0-1" }, "isoforms": [ { "isoform_ac": "A0A8V1ACZ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACZ0/entry#A0A8V1ACZ0-1", "sequence": { "sequence": "MKTDPRCPEPGGGSAPFVVRRLRAGRGRGRAGPEEFPRCPSATMGSAPYRSLLPLLPLLLSPLSLLPAVCGDCGPLPNISRAEPPEDVRHQDSFPVGSKVTYRCLQNFSKIPSRLDTIVCFNNSLWSNLQEFCDRSCQSPPQVPFAKLSAEDEMKNFYAVGTTVRYNCSRGYENSSAVLPSSTCQENSTWSEVPELCRKRSCGPPANPEHGKVLVTDHLYRARAEVVCDKGYTPSKKRPFITCFAEEDEVAWTPLPKCLASPSVSDTTAVTDSTTHLEEKASENNYILPLILVPSIIGLTSQIQGMKSRIHPKRSTGLRGVQGQQQPNPDSARILQWRNSVLRSRRFKLASDSAPSPFA", "length": 359, "header": "tr|A0A8V1ACZ0-1|A0A8V1ACZ0_CHICK Isoform 1 of CD55 molecule (Cromer blood group) OS=Gallus gallus OX=9031 GN=CD55 PE=4 SV=1 CANONICAL=A0A8V1ACZ0-1" }, "locus": { "chromosome": "26", "start_pos": 2692793, "end_pos": 2689441, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065842.1", "url": "https://www.ensembl.org/id/ENSGALT00010065842.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040108.1", "url": "https://www.ensembl.org/id/ENSGALP00010040108.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], 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"total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AD00-1", "uniprot_ac": "A0A8V1AD00", "uniprot_id": "A0A8V1AD00_CHICK", "mass": { "chemical_mass": 31454.0, "monoisotopic_mass": 31454.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Uncharacterized protein", "type": 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"length": 296, "header": "tr|A0A8V1AD00-1|A0A8V1AD00_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1AD00-1" }, "locus": { "chromosome": "28", "start_pos": 1543803, "end_pos": 1542916, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068325.1", "url": "https://www.ensembl.org/id/ENSGALT00010068325.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042068.1", "url": "https://www.ensembl.org/id/ENSGALP00010042068.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 246, "start_aa": "Thr", "end_pos": 246, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr246", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 269, "end_pos": 271, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 246 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 269, "end_pos": 271 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", 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} ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AD22", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD22" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "QRICH2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD22", "locus": {} } ], "crossref": [ { "id": "A0A8V1AD22", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AD22", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR032013", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032013", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AD22", "url": "https://www.orthodb.org/?gene=A0A8V1AD22", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46766", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46766", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46766:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46766:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF16043", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16043", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1AD22", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD22", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AD22-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD22-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": 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"length": 1068, "header": "tr|A0A8V1AD22-1|A0A8V1AD22_CHICK Isoform 1 of Glutamine rich 2 OS=Gallus gallus OX=9031 GN=QRICH2 PE=4 SV=1 CANONICAL=A0A8V1AD22-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AD22-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD22/entry#A0A8V1AD22-1", "sequence": { "sequence": 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"Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CSF1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD32", "locus": { "chromosome": "26", "start_pos": 1330072, "end_pos": 1323460, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027734", "url": "https://www.ensembl.org/id/ENSGALG00010027734" } ] } } ], "crossref": [ { "id": "A0A8V1AD32", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AD32", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000033854", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000033854", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100499189", "url": "https://www.ncbi.nlm.nih.gov/gene/100499189", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR008001", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008001", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009079", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009079", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "CQIAYEF", "url": "https://omabrowser.org/oma/group/CQIAYEF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PHN3", "url": "https://www.orthodb.org/?gene=A0A1D5PHN3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AD32", "url": "https://www.orthodb.org/?gene=A0A8V1AD32", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AFP5", "url": "https://www.orthodb.org/?gene=A0A8V1AFP5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10058", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10058", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10058:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10058:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05337", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05337", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-381426", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-381426", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-449836", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-449836", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-8957275", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8957275", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9856649", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9856649", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A1D5PHN3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PHN3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PHN3-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PHN3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AD32", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD32", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AD32-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD32-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFP5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFP5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFP5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFP5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPKQPSVERAPRVSLFRCTLLSSLLLVCSIHETEQNSYCQQIITERHLDHLQELADTQMQQPGTVSFRFISKMRLSDSVCYVKAAFPLLGTILNRTTFKENSTNANKMKTVRKMYENIDENVDPCIRDEDDEEHALSEMCFEEFTTSPYEMLVLVRQFFQDIKQLLQNKETFEKDCSQVYRSACAGPRQHSSSPGVGTDPDCNCLSPALPSATQPSLSAATRAGRDVAPASTRVPYRQLGGILAELGSSAPSEPPSSVEGSSGAEELPGAGLGDASAPSPTMQQTLGALLDPAASAGPKAEDVSIPSHGMPEEGAGTPALPHRLPSPRGISAAMPAAVPSSGSAQRRGVGRRPTESPERVTQLRFSRMAPPLRGRAEGGPGDGARARGWGLSRLREPEDGGAGPSFDSSFVLSAEQRRKEPPAASGGHRELLVYVTVASVVAVLLAMGGLLFYKYKSKVLQRGAALKEGGCDPEEPESRWVPSQRLAAGSGDPPAPTPTRGPRPHGLPYNPRCVLPRRALQGAQGCAELETQEL", "length": 534, "header": "tr|A0A8V1AD32-1|A0A8V1AD32_CHICK Isoform 1 of Colony stimulating factor 1 OS=Gallus gallus OX=9031 GN=CSF1 PE=4 SV=1 CANONICAL=A0A8V1AD32-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PHN3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD32/entry#A0A1D5PHN3-1", "sequence": { "sequence": "MPRLGSQVSLFRCTLLSSLLLVCSIHETEQNSYCQQIITERHLDHLQELADTQMQQPGTVSFRFISKMRLSDSVCYVKAAFPLLGTILNRTTFKENSTNANKMKTVRKMYENIDENVDPCIRDEDDEEHALSEMCFEEFTTSPYEMLVLVRQFFQDIKQLLQNKETFEKDCSQVYRSACAGPRQHSSSPGVGTDPDCNCLSPALPSATQPSLSAATRAGRDVAPASTRVPYRQLGGILAELGSSAPSEPPSSVEGSSGAEELPGAGLGDASAPSPTMQQTLGALLDPAASAGPKAEDVSIPSHGMPEEGAGTPALPHRLPSPRGISAAMPAAVPSSGSAQRRGVGRRPTESPERVTQLRFSRMAPPLRGRAEGGPGDGARARGWGLSRLREPEDGGAGPSFDSSFVLSAEQRRKEPPAASGGHRELLVYVTVASVVAVLLAMGGLLFYKYKSKVLQRGAALKEGGCDPEEPESRALQGAQGCAELETQEL", "length": 490, "header": "tr|A0A1D5PHN3-1|A0A1D5PHN3_CHICK Computationally mapped isoform of Colony stimulating factor 1 OS=Gallus gallus OX=9031 GN=CSF1 PE=4 SV=1 CANONICAL=A0A8V1AD32-1" }, "locus": { "chromosome": "26", "start_pos": 1328625, "end_pos": 1323564, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067231.1", "url": "https://www.ensembl.org/id/ENSGALT00010067231.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041135.1", "url": "https://www.ensembl.org/id/ENSGALP00010041135.1" } ] } }, { "isoform_ac": "A0A8V1AD32-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD32/entry#A0A8V1AD32-1", "sequence": { "sequence": "MPKQPSVERAPRVSLFRCTLLSSLLLVCSIHETEQNSYCQQIITERHLDHLQELADTQMQQPGTVSFRFISKMRLSDSVCYVKAAFPLLGTILNRTTFKENSTNANKMKTVRKMYENIDENVDPCIRDEDDEEHALSEMCFEEFTTSPYEMLVLVRQFFQDIKQLLQNKETFEKDCSQVYRSACAGPRQHSSSPGVGTDPDCNCLSPALPSATQPSLSAATRAGRDVAPASTRVPYRQLGGILAELGSSAPSEPPSSVEGSSGAEELPGAGLGDASAPSPTMQQTLGALLDPAASAGPKAEDVSIPSHGMPEEGAGTPALPHRLPSPRGISAAMPAAVPSSGSAQRRGVGRRPTESPERVTQLRFSRMAPPLRGRAEGGPGDGARARGWGLSRLREPEDGGAGPSFDSSFVLSAEQRRKEPPAASGGHRELLVYVTVASVVAVLLAMGGLLFYKYKSKVLQRGAALKEGGCDPEEPESRWVPSQRLAAGSGDPPAPTPTRGPRPHGLPYNPRCVLPRRALQGAQGCAELETQEL", "length": 534, "header": "tr|A0A8V1AD32-1|A0A8V1AD32_CHICK Isoform 1 of Colony stimulating factor 1 OS=Gallus gallus OX=9031 GN=CSF1 PE=4 SV=1 CANONICAL=A0A8V1AD32-1" }, "locus": { "chromosome": "26", "start_pos": 1328625, "end_pos": 1324188, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067229.1", "url": "https://www.ensembl.org/id/ENSGALT00010067229.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041133.1", "url": "https://www.ensembl.org/id/ENSGALP00010041133.1" } ] } }, { "isoform_ac": "A0A8V1AFP5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD32/entry#A0A8V1AFP5-1", "sequence": { "sequence": "MGVGWEDCSRVSLFRCTLLSSLLLVCSIHETEQNSYCQQIITERHLDHLQELADTQMQQPGTVSFRFISKMRLSDSVCYVKAAFPLLGTILNRTTFKENSTNANKMKTVRKMYENIDENVDPCIRDEDDEEHALSEMCFEEFTTSPYEMLVLVRQFFQDIKQLLQNKETFEKDCSQVYRSACAGPRQHSSSPGPVLPPVLVRVPRCCVCMPVEEVSQCCLRRAVPCHRRTVGMSPWPAPASDAASWITPHCQLRGPGDGLPLVLSPLSCCHVRPCLLPACSLLPSALLFGAFALAGTRGDPRLGPAACR", "length": 309, "header": "tr|A0A8V1AFP5-1|A0A8V1AFP5_CHICK Computationally mapped isoform of Colony stimulating factor 1 OS=Gallus gallus OX=9031 GN=CSF1 PE=4 SV=1 CANONICAL=A0A8V1AD32-1" }, "locus": { "chromosome": "26", "start_pos": 1327362, "end_pos": 1324368, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067228.1", "url": "https://www.ensembl.org/id/ENSGALT00010067228.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041132.1", "url": "https://www.ensembl.org/id/ENSGALP00010041132.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 497, "start_aa": "Thr", "end_pos": 497, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr497", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-GGA-381426", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-381426", "resource": "Reactome", "description": "Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)" }, { "id": "R-GGA-449836", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-449836", "resource": "Reactome", "description": "Other interleukin signaling" }, { "id": "R-GGA-8957275", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8957275", "resource": "Reactome", "description": "Post-translational protein phosphorylation" }, { "id": "R-GGA-9856649", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9856649", "resource": "Reactome", "description": "Transcriptional and post-translational regulation of MITF-M expression and activity" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287BPE2-1", "protein_name": "Macrophage colony-stimulating factor 1", "gene_name": "CSF1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTAPGAAGRCPPTTWLGPLLLLVCLLVSRSTAEEVSENCSHMIGDGHLKVLQQLIDSQMETSCQIAFEFVDQEQLTDPVCYLKKAFLQVQDILDETMRFRDNTPNANVIVQLQELSLRLNSCFTKDYEEQDKACVRTFYETPLQLLEKIKNVFNETKNLLKKDWNIFSKNCNNSFAKCSSQDVVTKPDCNCLYPKATPSSDLASVSPQQPLTPFMAPVVGLTWADSEGTEGSSLLPQEQPPRTVDPGGAKQRPPRSTCQTFESSETPGVEDSSTGGSPQPHSSVGAPITGMEDILGSMLGTDLALEEASGEASEGPLPLGAEPSPSRLQGDSVQAERARPSHLLSAFSPLSGPAKGWQPADVISPLPPTGATGRPTEAWSHTLEKTVHPSALPRDRLEPDSTRIPAPHPRSLSSPSTLSSQPGLPGSRPWGHVLSPGEPEGKRSTRDRRSPAELEGGQAIEGAPRHLAYFNPIPLTDAGHERQPEGRSDPQLPGFVLRLLVPSIILVLLAVGGLLFYRRRRWSLREPWTVDPPMEQPEGSPLTQDEDRQVELPV", "length": 554 }, "evidence": [ { "id": "A0A8V1AD32", "url": "https://omabrowser.org/oma/group/A0A8V1AD32/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1MGS9-1", "protein_name": "Macrophage colony-stimulating factor 1", "gene_name": "CSF1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTARGAAGRCPPTTWLGPLLLLACLLVSNGATEEVSENCSHMIGNGHLLFLQQLIDSQMETSCQISFEFVDQEQLDDPVCYLKKAFLLVQDIMEDTMRFKDNTPNAKVIVQLQELSLRLKSCFTMDYDEQDKACVRTFHETPLQLLEKIKNVFNETKNLLKKDWNIFSKNCNNSFAKCSSHDVVTKPDCNCLYPKATPSSDLASVSPQQSPTPSTAPMAGLTWADSEATDGSSLLPREQALRTVDPGSAKQRPPRSTCQSFESPETPRVEGRPTGDSPQPGPSVGAPVTGMEDVLDSLLGANIALEEASGEASEGPIPQGAELSFYSLGGRSVQAEPASPSHTPPASSALSGSGKGLRLVDATSAHLPTLGPMRPTEAWSHTPEKTERPSASPRDHQEPDMAKTPALHPQGLSSPSALSSQPKLPRSHSWGHVLSLGELEGRRSTRDRRSLAELKGGQASEGAARPPARFNSVPLTDTGHERQHKEASDPQLPGFVFRLLVPSIILVLLAVGGLLFYRRRRRSHQEPQMVDSPMEQPEGSLLTQEEDRQEELPV", "length": 554 }, "evidence": [ { "id": "A0A8V1AD32", "url": "https://omabrowser.org/oma/group/A0A8V1AD32/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3IHR6-1", "protein_name": "Macrophage colony-stimulating factor 1", "gene_name": "Csf1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MTARGAAGRCPSSTWLGPRLLLVCLLVSRSIAKEVSEHCSHMIGNGHLQILQQLIDSQMETSCQMEFEFVDQEQLDDPVCYLKKAFFLVKDIIEYKMRFKGNTPNANATERLQELSLRLKSCFTDDYEEQNKACVRTFHQTPLELLERIKNVFNETKHLLEKDWNIFSKNCNKSFAKCSSQDVVTKPDCNCLYPKATPSSDLASTSPHKPPAPSMAPLAGLAWDDSQRTEGNSLLPSEQPLRTEDPGSAKQRPPRSTCQSLESPEIPNHEDRLTEGSESPPSSEAPIPGVEDILESSLGTNWVLEEASGEASEGFLTQEAKLSSSKPVGDSIQAETDSSSNFSASSPLHKSTEDQQPAETSTPLPEVNAMRPTSQIQNHTPEKTDGSSTLPGNHQEPGSPHISTLGPQGLRNPATPFAQSLLPRSHSWGIVLPLGEFEGKRSTRDRRSPAELEGGPASEGAARPVAHFNSIPLTDTGKKGQRGGPNDPQISEFVFHLLVPGIILVLLAVGGLLFYRWKRRIHREPQTLDSFVGRPEDSPLTQDEDRQVELPV", "length": 552 }, "evidence": [ { "id": "A0A8V1AD32", "url": "https://omabrowser.org/oma/group/A0A8V1AD32/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P07141-1", "protein_name": "Macrophage colony-stimulating factor 1", "gene_name": "Csf1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTARGAAGRCPSSTWLGSRLLLVCLLMSRSIAKEVSEHCSHMIGNGHLKVLQQLIDSQMETSCQIAFEFVDQEQLDDPVCYLKKAFFLVQDIIDETMRFKDNTPNANATERLQELSNNLNSCFTKDYEEQNKACVRTFHETPLQLLEKIKNFFNETKNLLEKDWNIFTKNCNNSFAKCSSRDVVTKPDCNCLYPKATPSSDPASASPHQPPAPSMAPLAGLAWDDSQRTEGSSLLPSELPLRIEDPGSAKQRPPRSTCQTLESTEQPNHGDRLTEDSQPHPSAGGPVPGVEDILESSLGTNWVLEEASGEASEGFLTQEAKFSPSTPVGGSIQAETDRPRALSASPFPKSTEDQKPVDITDRPLTEVNPMRPIGQTQNNTPEKTDGTSTLREDHQEPGSPHIATPNPQRVSNSATPVAQLLLPKSHSWGIVLPLGELEGKRSTRDRRSPAELEGGSASEGAARPVARFNSIPLTDTGHVEQHEGSSDPQIPESVFHLLVPGIILVLLTVGGLLFYKWKWRSHRDPQTLDSSVGRPEDSSLTQDEDRQVELPV", "length": 552 }, "evidence": [ { "id": "A0A8V1AD32", "url": "https://omabrowser.org/oma/group/A0A8V1AD32/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P09603-1", "protein_name": "Macrophage colony-stimulating factor 1", "gene_name": "CSF1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTAPGAAGRCPPTTWLGSLLLLVCLLASRSITEEVSEYCSHMIGSGHLQSLQRLIDSQMETSCQITFEFVDQEQLKDPVCYLKKAFLLVQDIMEDTMRFRDNTPNAIAIVQLQELSLRLKSCFTKDYEEHDKACVRTFYETPLQLLEKVKNVFNETKNLLDKDWNIFSKNCNNSFAECSSQDVVTKPDCNCLYPKAIPSSDPASVSPHQPLAPSMAPVAGLTWEDSEGTEGSSLLPGEQPLHTVDPGSAKQRPPRSTCQSFEPPETPVVKDSTIGGSPQPRPSVGAFNPGMEDILDSAMGTNWVPEEASGEASEIPVPQGTELSPSRPGGGSMQTEPARPSNFLSASSPLPASAKGQQPADVTGTALPRVGPVRPTGQDWNHTPQKTDHPSALLRDPPEPGSPRISSLRPQGLSNPSTLSAQPQLSRSHSSGSVLPLGELEGRRSTRDRRSPAEPEGGPASEGAARPLPRFNSVPLTDTGHERQSEGSFSPQLQESVFHLLVPSVILVLLAVGGLLFYRWRRRSHQEPQRADSPLEQPEGSPLTQDDRQVELPV", "length": 554 }, "evidence": [ { "id": "A0A8V1AD32", "url": "https://omabrowser.org/oma/group/A0A8V1AD32/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8JZQ0-1", "protein_name": "Macrophage colony-stimulating factor 1", "gene_name": "Csf1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTARGAAGRCPSSTWMGSRLLLVCLLVSRSVAEVSEHCSHMIGNGHLQILQQLIDSQMETACLIEYKFVDQEQLDDPVCYLKKAFVLVQVIIEETMRFKDNTPNANATERLQELSMKLNSCFIKDYKEQNEACVQTYKESPLRLLEKIKNFFNETKNFLEKDWNIFSKNCNDSFAKCSSRDVVTKPDCNCLYPKATPSSDLASASPHQPPAPSMAPLADLAWDDSQRTEGSSLLPSDLPLRIEDPGSAKQRPPRSTCQTLESTEQPNHEDPQPHPSAGAPIPGVEDIIESSMGTNWVLEEASGEASEGFLTQERKFSPSNPVGGSIQAETDRPWARSASSPFPKLTEDQQPTNITDTPLTEVNPMRPTGQTLNNTPEKTDGSSTLREDQQEPRSPHFATLNPQRVGNSATPYAKLLPPKSHSWGIVLPLGELEGKKSTRDRRSPAELKGGPASEGAARPVAQSTRDRRSPAELKGGPASEGAARPVARFNSIPLTDTGSSIQDPQTSAFVFWVLGIILVLLAVGGLLFYSWKRRSHRDPRTLDSSVGRPEGSSLAQDEDRQVELPV", "length": 566 }, "evidence": [ { "id": "A0A8V1AD32", "url": "https://omabrowser.org/oma/group/A0A8V1AD32/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "osteoclast differentiation", "id": "GO:0030316", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030316", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AD32", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD32" } ], "pmid": "" }, { "name": "positive regulation of macrophage differentiation", "id": "GO:0045651", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045651", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AD32", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD32" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AD32", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD32" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AD32", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD32" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "cytokine activity", 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This record is derived from a genomic sequence (NC_052550.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. 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"https://www.ebi.ac.uk/interpro/entry/IPR051291", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "FKRAPAW", "url": "https://omabrowser.org/oma/group/FKRAPAW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR21580", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21580", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21580:SF28", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21580:SF28", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "XP_040506245", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040506245", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AD75", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD75", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AD75-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD75-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPASMDGAWVGTWRPHRPRGLISAQFPSPGPQYSIPGTTGYVGHSPTKARAPAYTFRGTKPPAAGSCGPGPCYFVEPAITRNGKYVAPGAQLRGRPATKTTVTPGPSDYRTEAANRHVFKCPPVQSMAFRREPLRTDHPPGPGTYTLPRLMGPTQSTHRPALLLCEGKEPARSV", "length": 174, "header": "tr|A0A8V1AD75-1|A0A8V1AD75_CHICK Isoform 1 of ODF3A protein OS=Gallus gallus OX=9031 GN=LOC121107249 PE=4 SV=1 CANONICAL=A0A8V1AD75-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AD75-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD75/entry#A0A8V1AD75-1", "sequence": { "sequence": "MPASMDGAWVGTWRPHRPRGLISAQFPSPGPQYSIPGTTGYVGHSPTKARAPAYTFRGTKPPAAGSCGPGPCYFVEPAITRNGKYVAPGAQLRGRPATKTTVTPGPSDYRTEAANRHVFKCPPVQSMAFRREPLRTDHPPGPGTYTLPRLMGPTQSTHRPALLLCEGKEPARSV", "length": 174, "header": "tr|A0A8V1AD75-1|A0A8V1AD75_CHICK Isoform 1 of ODF3A protein OS=Gallus gallus OX=9031 GN=LOC121107249 PE=4 SV=1 CANONICAL=A0A8V1AD75-1" }, "locus": { "chromosome": "19", "start_pos": 509975, "end_pos": 508153, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071288.1", "url": "https://www.ensembl.org/id/ENSGALT00010071288.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043979.1", "url": "https://www.ensembl.org/id/ENSGALP00010043979.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 103, "start_aa": "Thr", "end_pos": 103, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr103", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 154, "start_aa": "Thr", "end_pos": 154, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr154", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 103, 154 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { 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"sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AD78-1", "uniprot_ac": "A0A8V1AD78", "uniprot_id": "A0A8V1AD78_CHICK", "mass": { "chemical_mass": 8647.0, "monoisotopic_mass": 8647.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "A0A8V1AD78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD78/entry#names_and_taxonomy" } ] } ], "function": [], 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"header": "tr|A0A8V1AD78-1|A0A8V1AD78_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1AD78-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AD78-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD78/entry#A0A8V1AD78-1", "sequence": { "sequence": "SCTKASHPTSKLTGRSGQYWLPPGATWEDMKESADTHYPKPQDLWLCLPGALLLIVVRCIFERWVAQIQLLLSAPQP", "length": 77, "header": "tr|A0A8V1AD78-1|A0A8V1AD78_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1AD78-1" }, "locus": { "chromosome": "28", "start_pos": 507020, "end_pos": 506372, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068454.1", "url": "https://www.ensembl.org/id/ENSGALT00010068454.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042134.1", "url": "https://www.ensembl.org/id/ENSGALP00010042134.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": 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0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AD82-1", "uniprot_ac": "A0A8V1AD82", "uniprot_id": "A0A8V1AD82_CHICK", "mass": { "chemical_mass": 34695.0, "monoisotopic_mass": 34695.0 }, "refseq": { "ac": "NP_001305933", "name": "uncharacterized protein LOC107055097", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001305933" }, "gene_names": [ { "name": "LOC107055097", "type": "recommended", "evidence": [ { "id": "A0A8V1AD82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD82" } ] }, { "name": "EDYM2", "type": "synonym", "evidence": [ { "id": "NP_001305933", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001305933" } ] }, { "name": "LOC107055097", "type": "synonym", "evidence": [ { "id": "NP_001305933", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001305933" } ] } ], "protein_names": [ { "name": "Epidermal differentiation protein", "type": "recommended", "evidence": [ { "id": "A0A8V1AD82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD82/entry#names_and_taxonomy" } ] }, { "name": "epidermal differentiation protein containing Y motif 2", "type": "synonym", "evidence": [ { "id": "NP_001305933", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001305933" } ] }, { "name": "uncharacterized protein LOC107055097", "type": "synonym", "evidence": [ { "id": "NP_001305933", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001305933" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMN02738215, SAMN02738216 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000349.1. On Dec 3, 2021 this sequence version replaced NP_001305933.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001305933", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001305933" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AD82", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD82" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC107055097", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD82", "locus": {} } ], "crossref": [ { "id": "107055097", "url": "https://www.ncbi.nlm.nih.gov/gene/107055097", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "gga:107055097", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:107055097", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TECPPQQ", "url": "https://omabrowser.org/oma/group/TECPPQQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AD82", "url": "https://www.orthodb.org/?gene=A0A8V1AD82", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "NP_001305933", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001305933", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AD82", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD82", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AD82-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD82-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MHYYGERYKQLYLPGSSYVTESHQHCTSQPDACSTTCHPLSIIKSPMPRWQSYVQPFTYVCSQPSVTHSTLLPCQPCVQQCVVLCPDPCETTCLLPCRKPSVRLSPAQPLQSCENGHLEKKRVAKSLPPCAPRCPEPGKLKFPPCGIRYSSSCKDECRSKKVSRCSSQRYGAENRCLQGMTSGYSLPLRGVTECPPQQCVTQCFMEEYISPFPHQKCSKGYPTQECITTCTQQQVPKCPPGSGVKGSSSQQHLAKCSLLQEGAKHKSSSAQHISKSKCLHPCAVQRSPRHHAGDVKRSSHSKKSRCASKWLW", "length": 312, "header": "tr|A0A8V1AD82-1|A0A8V1AD82_CHICK Isoform 1 of Epidermal differentiation protein OS=Gallus gallus OX=9031 GN=LOC107055097 PE=4 SV=1 CANONICAL=A0A8V1AD82-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AD82-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD82/entry#A0A8V1AD82-1", "sequence": { "sequence": "MHYYGERYKQLYLPGSSYVTESHQHCTSQPDACSTTCHPLSIIKSPMPRWQSYVQPFTYVCSQPSVTHSTLLPCQPCVQQCVVLCPDPCETTCLLPCRKPSVRLSPAQPLQSCENGHLEKKRVAKSLPPCAPRCPEPGKLKFPPCGIRYSSSCKDECRSKKVSRCSSQRYGAENRCLQGMTSGYSLPLRGVTECPPQQCVTQCFMEEYISPFPHQKCSKGYPTQECITTCTQQQVPKCPPGSGVKGSSSQQHLAKCSLLQEGAKHKSSSAQHISKSKCLHPCAVQRSPRHHAGDVKRSSHSKKSRCASKWLW", "length": 312, "header": "tr|A0A8V1AD82-1|A0A8V1AD82_CHICK Isoform 1 of Epidermal differentiation protein OS=Gallus gallus OX=9031 GN=LOC107055097 PE=4 SV=1 CANONICAL=A0A8V1AD82-1" }, "locus": { "chromosome": "25", "start_pos": 1342720, "end_pos": 1341785, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067297.1", "url": "https://www.ensembl.org/id/ENSGALT00010067297.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041180.1", "url": "https://www.ensembl.org/id/ENSGALP00010041180.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:107055097", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:107055097", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], 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OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1AD89-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AD89-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD89/entry#A0A8V1AD89-1", "sequence": { "sequence": "MKEKDLSTAPFAVQDVPALHCPGAGYAPNSGCSSSARSTVLPTRTAVQLLQLWGRGVWLHQPQPPRLCVIPPCSALCNLRSSLQMCVHTSACVCMHACACAHMQTHAHTCSHVHTHAHTCSHVQTHTHTLLPPSRSPSRSTLLHAEARRPQEVAIVTLPWRLIKLNMRAGTP", "length": 172, "header": "tr|A0A8V1AD89-1|A0A8V1AD89_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1AD89-1" }, "locus": { "chromosome": "18", "start_pos": 9722505, "end_pos": 9721752, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071303.1", "url": "https://www.ensembl.org/id/ENSGALT00010071303.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043994.1", "url": "https://www.ensembl.org/id/ENSGALP00010043994.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": 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"total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1ADA3-1", "uniprot_ac": "A0A8V1ADA3", "uniprot_id": "A0A8V1ADA3_CHICK", "mass": { "chemical_mass": 66100.0, "monoisotopic_mass": 66100.0 }, "refseq": {}, "gene_names": [ { "name": "BTBD17", "type": "recommended", "evidence": [ { "id": "A0A8V1ADA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADA3" } ] } ], "protein_names": [ { "name": "BTB domain containing 17", "type": "synonym", "evidence": [ { "id": "A0A8V1ADA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADA3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADA3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADA3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "BTBD17", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADA3", "locus": { "chromosome": "18", "start_pos": 9755216, "end_pos": 9767215, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029502", "url": "https://www.ensembl.org/id/ENSGALG00010029502" } ] } } ], "crossref": [ { "id": "A0A8V1ADA3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1ADA3", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd18292", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18292", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18493", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18493", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "427813", "url": "https://www.ncbi.nlm.nih.gov/gene/427813", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011705", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011705", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051481", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051481", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056184", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056184", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:427813", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427813", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1ADA3", "url": "https://www.orthodb.org/?gene=A0A8V1ADA3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ANY9", "url": "https://www.orthodb.org/?gene=A0A8V1ANY9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24410", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24410", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24410:SF12", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24410:SF12", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00651", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00651", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07707", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07707", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23651", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23651", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1ADA3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADA3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ADA3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADA3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ANY9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANY9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ANY9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANY9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNTHELGEPGGCTHCALNAKARRVPAAQRAVAAHGAGAVRRQRPHVVPGARWSTTPWDVGLGAGVGWIGAGSRSLGNGGSQFPPIDVAVRAGGARGLHKHPSGTARPVPRRAAGRCETMARLTGTRPTAARRWGCAATAFLLLLLTVQAAQKADLGGDATAATINHSLTLLQRLQELLQNGNSSDSVLRVRTAASDEAKVFHTHQLLLSLQSEVFEGLLRNQSVVTLHEPPETAALFEKFIRYLYCGGVSLLLHQAIPLHQLASKYRVWGLQRGVADYMRSHLASESSQGHVVGWYHYAARIGDAALQESCLQFLAWNLSSVLGSAEWASVSVELLLLLLERSDLVLHSELELYTAVEAWLARRQPEDAVAERVLRAIRYPMIAPSQLFRLQTQSAVLVRHYGAVQDLLFQAFQFHSASPLHFAKYFDVNCSMFLPRNYLAPSWGSQWVINNPARDDRSTSFQTQLGPSSHDSGKRVTWNVLFSPRWLPVSLRPVYSDSVSSAIQPVRIEDGRPRLVVTPATSSPDFAGVSFQKTVLVGVRQQGRIFVKHAYSFHQSSDETADFLAHADLQKRTSEYLIDNALHLHIIIKPVYHSLIKVKK", "length": 601, "header": "tr|A0A8V1ADA3-1|A0A8V1ADA3_CHICK Isoform 1 of BTB domain containing 17 OS=Gallus gallus OX=9031 GN=BTBD17 PE=4 SV=1 CANONICAL=A0A8V1ADA3-1" }, "isoforms": [ { "isoform_ac": "A0A8V1ADA3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADA3/entry#A0A8V1ADA3-1", "sequence": { "sequence": "MNTHELGEPGGCTHCALNAKARRVPAAQRAVAAHGAGAVRRQRPHVVPGARWSTTPWDVGLGAGVGWIGAGSRSLGNGGSQFPPIDVAVRAGGARGLHKHPSGTARPVPRRAAGRCETMARLTGTRPTAARRWGCAATAFLLLLLTVQAAQKADLGGDATAATINHSLTLLQRLQELLQNGNSSDSVLRVRTAASDEAKVFHTHQLLLSLQSEVFEGLLRNQSVVTLHEPPETAALFEKFIRYLYCGGVSLLLHQAIPLHQLASKYRVWGLQRGVADYMRSHLASESSQGHVVGWYHYAARIGDAALQESCLQFLAWNLSSVLGSAEWASVSVELLLLLLERSDLVLHSELELYTAVEAWLARRQPEDAVAERVLRAIRYPMIAPSQLFRLQTQSAVLVRHYGAVQDLLFQAFQFHSASPLHFAKYFDVNCSMFLPRNYLAPSWGSQWVINNPARDDRSTSFQTQLGPSSHDSGKRVTWNVLFSPRWLPVSLRPVYSDSVSSAIQPVRIEDGRPRLVVTPATSSPDFAGVSFQKTVLVGVRQQGRIFVKHAYSFHQSSDETADFLAHADLQKRTSEYLIDNALHLHIIIKPVYHSLIKVKK", "length": 601, "header": "tr|A0A8V1ADA3-1|A0A8V1ADA3_CHICK Isoform 1 of BTB domain containing 17 OS=Gallus gallus OX=9031 GN=BTBD17 PE=4 SV=1 CANONICAL=A0A8V1ADA3-1" }, "locus": { "chromosome": "18", "start_pos": 9759582, "end_pos": 9756483, "strand": "+", "evidence": [ { "database": "Ensembl 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"locus": { "chromosome": "18", "start_pos": 9757787, "end_pos": 9756483, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071319.1", "url": "https://www.ensembl.org/id/ENSGALT00010071319.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044010.1", "url": "https://www.ensembl.org/id/ENSGALP00010044010.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:427813", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427813", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 165, "end_pos": 167, "annotation": "n_glycosylation_sequon" }, { "start_pos": 182, "end_pos": 184, "annotation": "n_glycosylation_sequon" }, { "start_pos": 221, "end_pos": 223, "annotation": "n_glycosylation_sequon" }, { "start_pos": 318, "end_pos": 320, "annotation": "n_glycosylation_sequon" }, { 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"MFGILQLGKDSLPPSPRHTPGPTPLAAGAGPASASWTLTLHIRGPPRTPGLNETPHERWQWVWGADVKHYAVFVGHGSSRPGGPEGGGTERLNIQRILKVNRTLFVGDRDNVYRVSLEPTAGSEMRYHRKLTWRSNQHDISICRMKGKHEAECRNFIKVMLVRNQNLLFVCGTNAFNPICANYSMDTLEPIGDNISGMARCPYDPKHANVALFTGGMLFTATVTDFLAIDAVIYRSLGDSPTLRTVKHDSKWFKEPYFVHAVEWRSHVYFFFREIAMEFNYLEKVVVSRVARVCKNDMGGSQRVLEKQWTSFLKARLNCSVPGDSHFYFNVIHAVTDILELNGRPVVLAVFSTPTNSIPGSAVCAFDMTQVAAVFEGRFREQKSPESIWTAVPEDMVPKPRPGCCAAPGMRYNSSSTFPDEILTFVKTHPLMDEAVPSLGNAPWIVRTMSRYQLRKIVVDNAAGPWGNHTVVFLGSSTGTILKFLIHPNATSSPAPAPPGSQSVFLEEFETYQPGRCGRDTEDERRLLGLELDKAAGSLLLAFPPCVARVPVARCQQHSGCMKSCLGSRDPYCGWTPEGSCVFLEPSPRTAFEQDISGGSTSHLGECEGLVTESFVDEPDGLVSVNLLVISSVAAFVIGAVISGFSVCWFIGHRDRKELARRKDKETILAHSESVVSVSRLGERRARGGQPGALLAPLMPNGWPKELGKASQHDLDSGVLPTPEQTPLQQKRCPGALQNCTWEQSHNIINAALRDPGASGTRLHTGAGRSARGMPLSCHAILVDQELEAELSDSSGDGHWGRDHHEGPRTRQHPPAGARRPPRSSYGDFGGTPRPSPDRRRVVSAPGGEGGDFVEGPPWHPEQLNFNANNGTQRPGAHLKRNHTFNSGEAPAGGYGQHGTAPRAPGAGPPRALTDLHHLLRYGMERTPSGK", "length": 931, "header": "tr|A0A8V1ADC6-1|A0A8V1ADC6_CHICK Isoform 1 of Semaphorin-6B OS=Gallus gallus OX=9031 GN=SEMA6B PE=3 SV=1 CANONICAL=A0A8V1ADC6-1" }, "isoforms": [ { "isoform_ac": "A0A8V1ADC6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADC6/entry#A0A8V1ADC6-1", "sequence": { "sequence": "MFGILQLGKDSLPPSPRHTPGPTPLAAGAGPASASWTLTLHIRGPPRTPGLNETPHERWQWVWGADVKHYAVFVGHGSSRPGGPEGGGTERLNIQRILKVNRTLFVGDRDNVYRVSLEPTAGSEMRYHRKLTWRSNQHDISICRMKGKHEAECRNFIKVMLVRNQNLLFVCGTNAFNPICANYSMDTLEPIGDNISGMARCPYDPKHANVALFTGGMLFTATVTDFLAIDAVIYRSLGDSPTLRTVKHDSKWFKEPYFVHAVEWRSHVYFFFREIAMEFNYLEKVVVSRVARVCKNDMGGSQRVLEKQWTSFLKARLNCSVPGDSHFYFNVIHAVTDILELNGRPVVLAVFSTPTNSIPGSAVCAFDMTQVAAVFEGRFREQKSPESIWTAVPEDMVPKPRPGCCAAPGMRYNSSSTFPDEILTFVKTHPLMDEAVPSLGNAPWIVRTMSRYQLRKIVVDNAAGPWGNHTVVFLGSSTGTILKFLIHPNATSSPAPAPPGSQSVFLEEFETYQPGRCGRDTEDERRLLGLELDKAAGSLLLAFPPCVARVPVARCQQHSGCMKSCLGSRDPYCGWTPEGSCVFLEPSPRTAFEQDISGGSTSHLGECEGLVTESFVDEPDGLVSVNLLVISSVAAFVIGAVISGFSVCWFIGHRDRKELARRKDKETILAHSESVVSVSRLGERRARGGQPGALLAPLMPNGWPKELGKASQHDLDSGVLPTPEQTPLQQKRCPGALQNCTWEQSHNIINAALRDPGASGTRLHTGAGRSARGMPLSCHAILVDQELEAELSDSSGDGHWGRDHHEGPRTRQHPPAGARRPPRSSYGDFGGTPRPSPDRRRVVSAPGGEGGDFVEGPPWHPEQLNFNANNGTQRPGAHLKRNHTFNSGEAPAGGYGQHGTAPRAPGAGPPRALTDLHHLLRYGMERTPSGK", "length": 931, "header": "tr|A0A8V1ADC6-1|A0A8V1ADC6_CHICK Isoform 1 of Semaphorin-6B OS=Gallus gallus OX=9031 GN=SEMA6B PE=3 SV=1 CANONICAL=A0A8V1ADC6-1" }, "locus": { "chromosome": "28", "start_pos": 2991753, "end_pos": 2985226, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065983.1", "url": "https://www.ensembl.org/id/ENSGALT00010065983.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040249.1", "url": "https://www.ensembl.org/id/ENSGALP00010040249.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 23, "start_aa": "Thr", "end_pos": 23, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr23", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 722, "start_aa": "Thr", "end_pos": 722, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr722", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADC6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADC6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "semaphorin receptor binding", "id": "GO:0030215", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030215", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADC6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADC6" } ], "pmid": "" }, { "name": "chemorepellent activity", "id": "GO:0045499", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045499", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADC6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADC6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "positive regulation of cell migration", "id": "GO:0030335", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030335", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADC6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADC6" } ], "pmid": "" }, { "name": "semaphorin-plexin signaling pathway", "id": "GO:0071526", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071526", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADC6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADC6" } ], "pmid": "" }, { "name": "central nervous system development", "id": "GO:0007417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007417", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADC6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADC6" } ], "pmid": "" }, { "name": "neural crest cell migration", "id": "GO:0001755", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001755", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADC6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADC6" } ], "pmid": "" }, { "name": "axon guidance", "id": "GO:0007411", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007411", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADC6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADC6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 101, "end_pos": 103, "annotation": "n_glycosylation_sequon" }, { "start_pos": 182, "end_pos": 184, "annotation": "n_glycosylation_sequon" }, { "start_pos": 194, "end_pos": 196, "annotation": "n_glycosylation_sequon" }, { "start_pos": 318, "end_pos": 320, "annotation": "n_glycosylation_sequon" }, { "start_pos": 413, "end_pos": 415, "annotation": "n_glycosylation_sequon" }, { "start_pos": 468, "end_pos": 470, "annotation": "n_glycosylation_sequon" }, { "start_pos": 489, "end_pos": 491, "annotation": "n_glycosylation_sequon" }, { "start_pos": 52, "end_pos": 54, "annotation": "n_glycosylation_sequon" }, { "start_pos": 739, "end_pos": 741, "annotation": "n_glycosylation_sequon" }, { "start_pos": 870, "end_pos": 872, "annotation": "n_glycosylation_sequon" }, { "start_pos": 882, "end_pos": 884, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1ADC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADC6" }, { "id": "PS51004", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51004" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Sema", "eco_id": "ECO_0000259", "start_pos": 71, "end_pos": 552, "start_aa": "Ala", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 23, 722 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 101, "end_pos": 103 }, { "start_pos": 182, "end_pos": 184 }, { "start_pos": 194, "end_pos": 196 }, { "start_pos": 318, "end_pos": 320 }, { "start_pos": 413, "end_pos": 415 }, { "start_pos": 468, "end_pos": 470 }, { "start_pos": 489, "end_pos": 491 }, { "start_pos": 52, "end_pos": 54 }, { "start_pos": 739, "end_pos": 741 }, { "start_pos": 870, "end_pos": 872 }, { "start_pos": 882, "end_pos": 884 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1ADD4-1", "uniprot_ac": "A0A8V1ADD4", "uniprot_id": "A0A8V1ADD4_CHICK", "mass": { "chemical_mass": 27735.0, "monoisotopic_mass": 27735.0 }, "refseq": { "ac": "XP_004939123", "name": "leucine-rich repeat-containing protein 61", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004939123" }, "gene_names": [ { "name": "LRRC61", "type": "recommended", "evidence": [ { "id": "A0A8V1ADD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADD4" } ] }, { "name": "LRRC61", "type": "synonym", "evidence": [ { "id": "XP_004939123", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004939123" } ] } ], "protein_names": [ { "name": "Leucine rich repeat containing 61", "type": "synonym", "evidence": [ { "id": "A0A8V1ADD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADD4/entry#names_and_taxonomy" } ] }, { "name": "leucine-rich repeat-containing protein 61", "type": "synonym", "evidence": [ { "id": "XP_004939123", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004939123" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052533.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004939123.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004939123", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004939123" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADD4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADD4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LRRC61", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADD4", "locus": { "chromosome": "2", "start_pos": 446444, "end_pos": 451571, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027221", "url": "https://www.ensembl.org/id/ENSGALG00010027221" } ] } } ], "crossref": [ { "id": "428394", "url": "https://www.ncbi.nlm.nih.gov/gene/428394", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:428394", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428394", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YWESWPT", "url": "https://omabrowser.org/oma/group/YWESWPT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ADD4", "url": "https://www.orthodb.org/?gene=A0A8V1ADD4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR18849", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18849", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR18849:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18849:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14580", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14580", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004939123", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004939123", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1ADD4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADD4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ADD4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADD4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "METQTEKGEDGEGTRITAQLLKASTGEFALESILLLKLRGRGIADLGCLGDCTNLEWLDLSGNAISQLGPLAGLKALAVLNLSRNRISSLEPLSSCESLQSLNLAGNQVSSLQQLRCLAGLRRLESLRLRDALGQLSNPVCATAAYRAALPELLPGLRDIDGERVSGRGSELFQLCQDLDSSLGHGPGPAAPRAAQPWVQAGFWEPPPLRRSSIVEEAYRQFGEALRECRELGRRADDTIAQAERALSGRADPGSYVF", "length": 258, "header": "tr|A0A8V1ADD4-1|A0A8V1ADD4_CHICK Isoform 1 of Leucine rich repeat containing 61 OS=Gallus gallus OX=9031 GN=LRRC61 PE=4 SV=1 CANONICAL=A0A8V1ADD4-1" }, "isoforms": [ { "isoform_ac": "A0A8V1ADD4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADD4/entry#A0A8V1ADD4-1", "sequence": { "sequence": "METQTEKGEDGEGTRITAQLLKASTGEFALESILLLKLRGRGIADLGCLGDCTNLEWLDLSGNAISQLGPLAGLKALAVLNLSRNRISSLEPLSSCESLQSLNLAGNQVSSLQQLRCLAGLRRLESLRLRDALGQLSNPVCATAAYRAALPELLPGLRDIDGERVSGRGSELFQLCQDLDSSLGHGPGPAAPRAAQPWVQAGFWEPPPLRRSSIVEEAYRQFGEALRECRELGRRADDTIAQAERALSGRADPGSYVF", "length": 258, "header": "tr|A0A8V1ADD4-1|A0A8V1ADD4_CHICK Isoform 1 of Leucine rich repeat containing 61 OS=Gallus gallus OX=9031 GN=LRRC61 PE=4 SV=1 CANONICAL=A0A8V1ADD4-1" }, "locus": { "chromosome": "2", "start_pos": 449788, "end_pos": 449015, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065995.1", "url": "https://www.ensembl.org/id/ENSGALT00010065995.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040261.1", "url": "https://www.ensembl.org/id/ENSGALP00010040261.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:428394", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428394", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3L7H8K1-1", "protein_name": "Leucine-rich repeat-containing protein 61", "gene_name": "Lrrc61", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEPSGEKPGEAEGLSITPQLLKSRSGEFALDSILLLKLRGLGLVDLGCLGECLSLEWLDLSGNALTHLGPLAPLNQLAVLNVSNNRLTGLEPLAACENLQSLNVAGNLLATPGQLQCLAGLQGLEYLRLRDPLARLSNPLCATPSYWAVVRELLPGLKVIDGERVSGRGSDLYQLCRDLDSSLRRSSSPGPIAIEAQLWVDPDYWESCPMQSSSILEEACRQFQDTLQECLDLDRQAGDSLAQAQQALSAAEATSSVVF", "length": 259 }, "evidence": [ { "id": "A0A8V1ADD4", "url": "https://omabrowser.org/oma/group/A0A8V1ADD4/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "D3ZA60-1", "protein_name": "Leucine-rich repeat-containing protein 61", "gene_name": "Lrrc61", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEPPGEKPGEAEALIITPQLLKSHSGEFALDSILLLKLRGLGVVDLGCLGECLNLEWLDLSGNALTHLGPLASLHQLAVLNVSNNRLTGLEPLAACENLQSLNAAGNLLTNPGQLQCLAGLQGLEHLRLRDPLARLSNPLCVNPSYWAAVRELLPGLKVIDGERVSGRGSELYQLCRDLDSSLRSSTSLGPRAIEVQPWVEPGYWESWPIRSSSILEEACRQFQDTLQECLDLDRQASDSLAQAQQALRPAKTTSSFVF", "length": 259 }, "evidence": [ { "id": "A0A8V1ADD4", "url": "https://omabrowser.org/oma/group/A0A8V1ADD4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q2T9T5-1", "protein_name": "Leucine-rich repeat-containing protein 61", "gene_name": "LRRC61", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MEPRGEKSGEADGVRVTPQLLKARSGEFALESILLLKLRGLGLVGLGCLGDCLGLEWLDLSGNALTQLGPLASLRQLAVLNVADNRLTGLEPLAACENLQCLNAAGNLLAGPAQLQCLAGLRGLERLRLRDPLARLSNPLCASPCYWASVRELLPGLKVLDGERVSGRGSDFYQLCRDLDSSLSPDPGAPGPRPMEAQPWVEPGYWEALPPRSSSILEEACRQFQDTLQECHDLDRQAWDSLAQAMRALSPAGATAASFVF", "length": 261 }, "evidence": [ { "id": "A0A8V1ADD4", "url": "https://omabrowser.org/oma/group/A0A8V1ADD4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8R2R5-1", "protein_name": "Leucine-rich repeat-containing protein 61", "gene_name": "Lrrc61", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEPPGEKPGEAEALSITPQLLKSHSGEFALDSILLLKLRGLGVVDLGCLGECLNLEWLDLSGNALTHLGPLASLRQLAVLNVSNNRLTGLEPLAACENLQSLNAAGNLLTTPGQLQCLAGLQALEHLRLRDPLARLSNPLCANASYWAVVRELLPGLKVIDGERVSGRGSELYQLCRDLDSSLRSGSSPGPRAIEAQPWVEPGYWESWPIRSSSILEEACRQFQDTLQECLDLDRQASDSLAQAQQALSPAETTSSFVF", "length": 259 }, "evidence": [ { "id": "A0A8V1ADD4", "url": "https://omabrowser.org/oma/group/A0A8V1ADD4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9BV99-1", "protein_name": "Leucine-rich repeat-containing protein 61", "gene_name": "LRRC61", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDPPAEKPGEAGGLQITPQLLKSRTGEFSLESILLLKLRGLGLADLGCLGECLGLEWLDLSGNALTHLGPLASLRQLAVLNVSNNRLTGLEPLATCENLQSLNAAGNLLATPGQLQCLAGLPCLEYLRLRDPLARLSNPLCANPSYWAAVRELLPGLKVIDGERVIGRGSEFYQLCRDLDSSLRPSSSPGPRATEAQPWVEPGYWESWPSRSSSILEEACRQFQDTLQECWDLDRQASDSLAQAEQVLSSAGPTSSFVF", "length": 259 }, "evidence": [ { "id": "A0A8V1ADD4", "url": "https://omabrowser.org/oma/group/A0A8V1ADD4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 81, "end_pos": 83, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 81, "end_pos": 83 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1ADF3-1", "uniprot_ac": "A0A8V1ADF3", "uniprot_id": "A0A8V1ADF3_CHICK", "mass": { "chemical_mass": 31785.0, "monoisotopic_mass": 31785.0 }, "refseq": { "ac": "XP_003641426", "name": "leucine-rich repeat-containing protein 55", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003641426" }, "gene_names": [ { "name": "LRRC55", "type": "recommended", "evidence": [ { "id": "A0A8V1ADF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF3" } ] }, { "name": "LRRC55", "type": "synonym", "evidence": [ { "id": "XP_003641426", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003641426" } ] } ], "protein_names": [ { "name": "Leucine rich repeat containing 55", "type": "synonym", "evidence": [ { "id": "A0A8V1ADF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF3/entry#names_and_taxonomy" } ] }, { "name": "leucine-rich repeat-containing protein 55", "type": "synonym", "evidence": [ { "id": "XP_003641426", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003641426" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052536.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_003641426.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003641426", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003641426" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADF3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LRRC55", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF3", "locus": { "chromosome": "5", "start_pos": 16613659, "end_pos": 16617588, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010026523", "url": "https://www.ensembl.org/id/ENSGALG00010026523" } ] } } ], "crossref": [ { "id": "A0A8V1ADF3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1ADF3", "database": "AlphaFoldDB", "categories": [] }, { "id": "100858394", "url": "https://www.ncbi.nlm.nih.gov/gene/100858394", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000372", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000372", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000483", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000483", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003591", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003591", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051432", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051432", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:100858394", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100858394", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WSQLPWP", "url": "https://omabrowser.org/oma/group/WSQLPWP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ADF3", "url": "https://www.orthodb.org/?gene=A0A8V1ADF3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46473", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46473", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46473:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46473:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01462", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01462", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13855", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13855", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003641426", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003641426", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1ADF3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ADF3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGPGAGRRPAMLLGPWLVAVVAVVAVVAAGAGAGCPVLCTCRGQAVDCSGQRLFSVPAELPLDTGNLSLAHNRIASIPLGYLACYAQLRVLDLRNNSLAALPARLFLGARRLTHLDLSYNNFSLVTADMFLEASELLRLDLSHNPWLCTVHPRAFRGLAQLRELDLSYGGLSALSLDALEGLTGLVTLRIGGNPWVCGCAMEPFLKWLRSRIQLCTSDSQLAKCQAPPEVKEVPLFSLTEESFKACHLTLTLDDYLFIAFVGFVVSIASVATNFLLGITANCCHRWSKASEDEEV", "length": 295, "header": "tr|A0A8V1ADF3-1|A0A8V1ADF3_CHICK Isoform 1 of Leucine rich repeat containing 55 OS=Gallus gallus OX=9031 GN=LRRC55 PE=4 SV=1 CANONICAL=A0A8V1ADF3-1" }, "isoforms": [ { "isoform_ac": "A0A8V1ADF3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF3/entry#A0A8V1ADF3-1", "sequence": { "sequence": "MGPGAGRRPAMLLGPWLVAVVAVVAVVAAGAGAGCPVLCTCRGQAVDCSGQRLFSVPAELPLDTGNLSLAHNRIASIPLGYLACYAQLRVLDLRNNSLAALPARLFLGARRLTHLDLSYNNFSLVTADMFLEASELLRLDLSHNPWLCTVHPRAFRGLAQLRELDLSYGGLSALSLDALEGLTGLVTLRIGGNPWVCGCAMEPFLKWLRSRIQLCTSDSQLAKCQAPPEVKEVPLFSLTEESFKACHLTLTLDDYLFIAFVGFVVSIASVATNFLLGITANCCHRWSKASEDEEV", "length": 295, "header": "tr|A0A8V1ADF3-1|A0A8V1ADF3_CHICK Isoform 1 of Leucine rich repeat containing 55 OS=Gallus gallus OX=9031 GN=LRRC55 PE=4 SV=1 CANONICAL=A0A8V1ADF3-1" }, "locus": { "chromosome": "5", "start_pos": 16616711, "end_pos": 16615754, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010064454.1", "url": "https://www.ensembl.org/id/ENSGALT00010064454.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039538.1", "url": "https://www.ensembl.org/id/ENSGALP00010039538.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:100858394", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100858394", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3L7HFS6-1", "protein_name": "Leucine-rich repeat-containing protein 55", "gene_name": "Lrrc55", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MGSLQHCCCQLPKMGDTWAQLPWPGPLHPALLLVLFLLATGVMHSDAGTSCPVLCTCRNQVVDCSSQRLFSVPPDLPMDTRNLSLAHNRIAAVPPGYLTCYMELRVLDLRNNSLLELPQGLFLHAKRLAHLDLSYNNLSHVPADMFREAHGLVHIDLSHNPWLRRVHPQAFQGLVHLRDLDLSYGGLAFLSLEALEGLPGLVTLQIGGNPWVCGCTMEPLLKWLRNRIQRCTADSQLAECRGPPEVEGAPLFSLTEESFKACHLTLTLDDYLFIAFVGFVVSIASVATNFLLGITANCCHRWSKASEEEEI", "length": 311 }, "evidence": [ { "id": "A0A8V1ADF3", "url": "https://omabrowser.org/oma/group/A0A8V1ADF3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q3UY51-1", "protein_name": "Leucine-rich repeat-containing protein 55", "gene_name": "Lrrc55", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGDTWAQLPWPGPPHSALLLVFFLLAAGVMHSDAGTSCPVLCTCRNQVVDCSNQRLFSVPPDLPMDTRNLSLAHNRIAAVPPGYLTCYMELRVLDLRNNSLMELPPGLFLHAKRLAHLDLSYNNLSHVPADMFREAHGLVHIDLSHNPWLRRVHPQAFQGLVHLRDLDLSYGGLAFLSLEALEGLPGLVTLQIGGNPWVCGCTMEPLLKWLRNRIQRCTADSQLAECRGPPEVEGAPLFSLTEESFKACHLTLTLDDYLFIAFVGFVVSIASVATNFLLGITANCCHRWSKANEEEEI", "length": 298 }, "evidence": [ { "id": "A0A8V1ADF3", "url": "https://omabrowser.org/oma/group/A0A8V1ADF3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q4KLL3-1", "protein_name": "Leucine-rich repeat-containing protein 55", "gene_name": "Lrrc55", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGDTWAQLPWPGPPHSALLLVFFLLAAGVMHSDAGASCPVLCTCRNQVVDCSNQRLFSVPPDLPMDTRNLSLAHNRIAAVPPGYLTCYMELRVLDLRNNSLMELPPGLFLHAKRLAHLDLSYNNLSHVPADMFREAHGLVHIDLSHNPWLRRVHPQAFQGLVHLRDLDLSYGGLAFLSLEALEGLPGLVTLQIGGNPWVCGCTMEPLLKWLRNRIQRCTADSQLAECRGPPEVEGAPLFSLTEESFKACHLTLTLDDYLFIAFVGFVVSIASVATNFLLGITANCCHRWSKANEEEEI", "length": 298 }, "evidence": [ { "id": "A0A8V1ADF3", "url": "https://omabrowser.org/oma/group/A0A8V1ADF3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6ZSA7-1", "protein_name": "Leucine-rich repeat-containing protein 55", "gene_name": "LRRC55", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGDTWAQLPWPGPPHPAMLLISLLLAAGLMHSDAGTSCPVLCTCRNQVVDCSSQRLFSVPPDLPMDTRNLSLAHNRITAVPPGYLTCYMELQVLDLHNNSLMELPRGLFLHAKRLAHLDLSYNNFSHVPADMFQEAHGLVHIDLSHNPWLRRVHPQAFQGLMQLRDLDLSYGGLAFLSLEALEGLPGLVTLQIGGNPWVCGCTMEPLLKWLRNRIQRCTADSQLAECRGPPEVEGAPLFSLTEESFKACHLTLTLDDYLFIAFVGFVVSIASVATNFLLGITANCCHRWSKASEEEEI", "length": 298 }, "evidence": [ { "id": "A0A8V1ADF3", "url": "https://omabrowser.org/oma/group/A0A8V1ADF3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "transmembrane transporter binding", "id": "GO:0044325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044325", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADF3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF3" } ], "pmid": "" }, { "name": "voltage-gated potassium channel activity", "id": "GO:0005249", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005249", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADF3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF3" } ], "pmid": "" }, { "name": "potassium channel activator activity", "id": "GO:0099104", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099104", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADF3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "voltage-gated potassium channel complex", "id": "GO:0008076", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008076", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADF3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 121, "end_pos": 123, "annotation": "n_glycosylation_sequon" }, { "start_pos": 66, "end_pos": 68, "annotation": "n_glycosylation_sequon" }, { "start_pos": 95, "end_pos": 97, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1ADF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF3" }, { "id": "SM00082", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00082" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "LRRCT", "eco_id": "ECO_0000259", "start_pos": 193, "end_pos": 247, "start_aa": "Asn", "end_aa": "His", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1ADF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF3" }, { "id": "SM00013", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00013" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "LRRNT", "eco_id": "ECO_0000259", "start_pos": 34, "end_pos": 66, "start_aa": "Gly", "end_aa": "Asn", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 121, "end_pos": 123 }, { "start_pos": 66, "end_pos": 68 }, { "start_pos": 95, "end_pos": 97 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1ADF7-1", "uniprot_ac": "A0A8V1ADF7", "uniprot_id": "A0A8V1ADF7_CHICK", "mass": { "chemical_mass": 58913.0, "monoisotopic_mass": 58913.0 }, "refseq": { "ac": "XP_420075", "name": "AP-4 complex accessory subunit tepsin isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_420075" }, "gene_names": [ { "name": "TEPSIN", "type": "recommended", "evidence": [ { "id": "A0A8V1ADF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF7" } ] }, { "name": "TEPSIN", "type": "synonym", "evidence": [ { "id": "XP_420075", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_420075" } ] } ], "protein_names": [ { "name": "AP-4 complex accessory subunit tepsin isoform X1", "type": "synonym", "evidence": [ { "id": "XP_420075", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_420075" } ] }, { "name": "TEPSIN adaptor related protein complex 4 accessory protein", "type": "synonym", "evidence": [ { "id": "A0A8V1ADF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF7/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052549.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_420075.4. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_420075", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_420075" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADF7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TEPSIN", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF7", "locus": { "chromosome": "18", "start_pos": 9895170, "end_pos": 9890967, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029529", "url": "https://www.ensembl.org/id/ENSGALG00010029529" } ] } } ], "crossref": [ { "id": "A0A8V1ADF7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1ADF7", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd03572", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03572", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "422072", "url": "https://www.ncbi.nlm.nih.gov/gene/422072", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR008942", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008942", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013809", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013809", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035802", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035802", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039273", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039273", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058028", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058028", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "KASQRCP", "url": "https://omabrowser.org/oma/group/KASQRCP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ADF7", "url": "https://www.orthodb.org/?gene=A0A8V1ADF7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AKM5", "url": "https://www.orthodb.org/?gene=A0A8V1AKM5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21514", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21514", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21514:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21514:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01417", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01417", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25827", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25827", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_420075", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_420075", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1ADF7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ADF7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AKM5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKM5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AKM5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKM5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAVPLRDRLCFLSRLPVLLRGTADEEGPCPGFVLEEISKISRESAGSSQCLLEFLLGRLRSGSCHVKLKVLKILQHTCAQGSPQFLLQLRRNAAFIREAAAFTGPPDPLHGNSLNQKVRAAAQDLASFLFSDAALPTVTTLPARPLPPAGMGSKSSPCSSMQGFGFSSERGGSAGEALLSTIQRAAEAVASAVLPSPEGPPSHCGELHEDAYQPVTAPSPARSLASSTNPPAATTAHIARVSHQPGLAGGGWEEADSGHSSQNSSQENGDLSRTSDTYSKSGSDSHSGASRELVSGAERVDADSLGDCLREVSLVSALTQGARVFLTREEAQHFLKECGLLNCEVVLELLSRALEDPSDNVRMRSMSAISSLMCSDLLALDQIFAGTRQQLQQLSQGSPSPVANRATKILRQFEALCRGRPSPKPSRPRSAPSALAEGSAPCAGDLLTDIPPLPGESILQPLSAPTPPGSAPAVGTEPGLEAEPREQPGPTALPVPHGQEAARRSVGAVGTTAVPPHSPSLFAGMELMAPPGTALTPRTLPRPQDDTVPHPCNTEPSAFSFLNA", "length": 564, "header": "tr|A0A8V1ADF7-1|A0A8V1ADF7_CHICK Isoform 1 of TEPSIN adaptor related protein complex 4 accessory protein OS=Gallus gallus OX=9031 GN=TEPSIN PE=4 SV=1 CANONICAL=A0A8V1ADF7-1" }, "isoforms": [ { "isoform_ac": "A0A8V1ADF7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF7/entry#A0A8V1ADF7-1", "sequence": { "sequence": "MAVPLRDRLCFLSRLPVLLRGTADEEGPCPGFVLEEISKISRESAGSSQCLLEFLLGRLRSGSCHVKLKVLKILQHTCAQGSPQFLLQLRRNAAFIREAAAFTGPPDPLHGNSLNQKVRAAAQDLASFLFSDAALPTVTTLPARPLPPAGMGSKSSPCSSMQGFGFSSERGGSAGEALLSTIQRAAEAVASAVLPSPEGPPSHCGELHEDAYQPVTAPSPARSLASSTNPPAATTAHIARVSHQPGLAGGGWEEADSGHSSQNSSQENGDLSRTSDTYSKSGSDSHSGASRELVSGAERVDADSLGDCLREVSLVSALTQGARVFLTREEAQHFLKECGLLNCEVVLELLSRALEDPSDNVRMRSMSAISSLMCSDLLALDQIFAGTRQQLQQLSQGSPSPVANRATKILRQFEALCRGRPSPKPSRPRSAPSALAEGSAPCAGDLLTDIPPLPGESILQPLSAPTPPGSAPAVGTEPGLEAEPREQPGPTALPVPHGQEAARRSVGAVGTTAVPPHSPSLFAGMELMAPPGTALTPRTLPRPQDDTVPHPCNTEPSAFSFLNA", "length": 564, "header": "tr|A0A8V1ADF7-1|A0A8V1ADF7_CHICK Isoform 1 of TEPSIN adaptor related protein complex 4 accessory protein OS=Gallus gallus OX=9031 GN=TEPSIN PE=4 SV=1 CANONICAL=A0A8V1ADF7-1" }, "locus": { "chromosome": "18", "start_pos": 9894809, "end_pos": 9891016, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071375.1", "url": "https://www.ensembl.org/id/ENSGALT00010071375.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044065.1", "url": "https://www.ensembl.org/id/ENSGALP00010044065.1" } ] } }, { "isoform_ac": "A0A8V1AKM5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF7/entry#A0A8V1AKM5-1", "sequence": { "sequence": "MAVPLRDRLCFLSRLPVLLRGTADEEGPCPGFVLEEISKISRESAGSSQCLLEFLLGRLRSGSCHVKLKVLKILQHTCAQGSPQFLLQLRRNAAFIREAAAFTGPPDPLHGNSLNQKVRAAAQDLASFLFSDAALPTVTTLPARPLPPAGMGSKSSPCSSMQGFGFSSERGGSAGEALLSTIQRAAEAVASAVLPSPEGPPSHCGELHEDAYQPVTAPSPARSLASSTNPPAATTAHIARVSHQPGLAGGGWEEADSGHSSQNSSQENGDLSRTSDTYSKSGSDSHSGASRELVSGAERVDADSLGDCLREVSLVSALTQGARVFLTREEAQHFLKECGLLNCEVVLELLSRALEDPSDNVRMRSMSAISSLMCSDLLALDQIFAGTRQQLQQLSQGSPSPVANRATKILRQFEALCRGRPSPKPSRPRSAPSALAEGSAPCAGDLLTDIPPLPGESILQPLSAPTPPGSAPAVGTEPGLEAEPREQPGPTALPVPHGQEAARRALGLLLPQCIAAPGLPRGCRRWLWGSAWASHRQAALWRRGQRGCVWALPRSCRV", "length": 558, "header": "tr|A0A8V1AKM5-1|A0A8V1ADF7_CHICK Computationally mapped isoform of TEPSIN adaptor related protein complex 4 accessory protein OS=Gallus gallus OX=9031 GN=TEPSIN PE=4 SV=1 CANONICAL=A0A8V1ADF7-1" }, "locus": { "chromosome": "18", "start_pos": 9894943, "end_pos": 9891016, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071374.1", "url": "https://www.ensembl.org/id/ENSGALT00010071374.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044064.1", "url": "https://www.ensembl.org/id/ENSGALP00010044064.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 466, "start_aa": "Thr", "end_pos": 466, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr466", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 491, "start_aa": "Thr", "end_pos": 491, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr491", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1MCN3-1", "protein_name": "AP-4 complex accessory subunit Tepsin", "gene_name": "TEPSIN", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAAMPPLRDRLSFLHRLPILLKGTSDDDVPCPGYLFEEIAKISHESLGSSQCLLEYLLNRLHSGSGRVKLKVLKILLHLCGHGSSSFLLILKRNPAFIQEAAVFAGPPDPLHGNSLYQKVRAAAQDLGAALYSDALSPPPPSQPPRTLPPAGMGSQSRPQSALQGFGYSKERAHTGSAGEAFLSTIQKAAEVVASAVRPGPESPSCQRSLPRGDTYQPAVTPSTSLGTHASGSSLPAASPGARAARHQPGQAGGGWDELDSSPSSQDSSQENDDLGKASDSGSRSGSDSPSGASRAPSDLAERVEAVTLSDCQQELSLVRTVTQGQHTFLSREEVQHFVKECGLLNCEAVLELLIRHLAATSERVQMRALGAIASLGCTDLLSQERVLLLTRPRLQELSAGSPGPVTNKATKILRHFEASCRQWPPSRRSPAEPGPAAAHVGPSDLLTDTLPFTGGPAFLQPLSSALFFPKGSAPPSGLQPSPVPPTSPDSCPLPVPGAGRDAETGLAGSTDQGAASEQGPLYMDTPKGGPEIGLGLSHSCSSLFAGMELVACPRLVGAGTAAEEPLPAHQAPWTLSQRLAAKEPSGSEPSAFTFLNS", "length": 598 }, "evidence": [ { "id": "A0A8V1ADF7", "url": "https://omabrowser.org/oma/group/A0A8V1ADF7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "E7F390-1", "protein_name": "AP-4 complex accessory subunit tepsin", "gene_name": "tepsin", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MVSILERLVFLQKVPTLMRATSDDESPCPGYLFEEISKISHESVGCCQCLLEYLLERLQVESCHVKLKVLKILLHVCGHGPPHFLTELRRNATFIQEVIVYSGPPDPIHGNALYQKVRSSAQELASLLFNDSMSPDSVSSPHKSMTHSVGMGSESLRSGMQGFGSSPGRKESTSGTLLDKIQKAAEVVASAVLPPTEHPGLRLHDNHYHAVVAPSAAVEIAVPACAYNIQSHSHRTSHRCPGQAGGGWEETDSGHSSSHNSSQEIAEASQASMGRSSKSGGSGSHSGASRESGDLSERVEAIQLGDCGQETALINKLTSGSKVFLSREESQHFIKECSTLNCEVVVELLSRKLQDHTQIVQMRALCALACLMSSDFLSLDHIFNIIHKRLAQLSEGTTGPVANKATKLLRQFEALLGCVTNPRFDRIGRSSSTNLSSSDQPSTSITIPFISGQTGEPTTPVIPSEMAFTQGNSTAPGSHMNREQEEGEHRNTDTSKSSDPSRLSLFSGMELVNRSKPVCLVEPVPVDAQPCGEATTDTDCALEKRTAGSSTSAEQLSAFSFLNL", "length": 564 }, "evidence": [ { "id": "A0A8V1ADF7", "url": "https://omabrowser.org/oma/group/A0A8V1ADF7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "I3L691-1", "protein_name": "AP-4 complex accessory subunit Tepsin", "gene_name": "TEPSIN", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAATPQLRDRLSFLHRLPLLLKGTSDDDTPCPGFLFEEIAKISHESLGSSQCLLEYLLSRLHSGSGRVKLKVLKILLHLCGHGSSASLLILRRNPAFIQEAAVFAGPPDPLHGNSLYQKVRAAAQDLGAALFSDALSPPPPSQPPRAPPPAGMGSQSRPQSALQGFGYSKDQRHTGSAGEAFLSTIQKAAEVVASAVRPGPESPGTQRPLPQGDAYQPAMTPSAGLGPPPGDPLPTAGPAARAVRHQPGQAGGGWDEPDSSPSSQNSSQESSDLGKASDSGSQSGSDSPSGASRAPSDLAERVEAVTLSDCQQELSLVQAVTRGLQTFLSREEVQHFVKECGVLNCEAVLELLLRHLGGTSERVQMRALGAIASLGCTDLLAQERVLLLARPRLQELSAGSPGPVTNKATKILRHFEASCRQWPPARRPLAEPGPAAARGGPSDLLTDALPLAGGQAFLQPLSSALFSSRGTAVPATALDGCSPPAPGDAREAEARLAASREQGSGSEWDPSGLDTPTGAPGLGPGPRLGHDSLFAGMELVACPRLVGAGAAEEEPLPAPWTASQRPAAQEPSGSEPSAFAFLNV", "length": 585 }, "evidence": [ { "id": "A0A8V1ADF7", "url": "https://omabrowser.org/oma/group/A0A8V1ADF7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q3U3N6-1", "protein_name": "AP-4 complex accessory subunit Tepsin", "gene_name": "Tepsin", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAVPPLRDRLSFLHRLPILLKGTSDDSIPCPGYLFEEIAKISHESLGSSQCLLEYLLNRLDSSSGHVKLKVLKILLYLCGHGSSSFLLILRRNSALIQEATAFSGPPDPLHGNSLYQKVRAAAQDLGSTLFSDAVPQPPSQPPQIPPPAGMGAQARPLSALQGFGYTKESSRTGSAGETFLSTIQRAAEVVANAVRPGPDNPCTKGPLPYGDSYQPAVTPSASHTHPNPGNLLPGAILGARAVRHQPGQAGGGWDELDSSPSSQNSSCTSNLSRASDSGSRSGSDSHSGTSREPGDLAERAEATPPNDCQQELNLVRTVTQGPRVFLSREETQHFIKECGLLNCEAVLELLLRQLVGTSECEQMRALCAIASFGSADLLPQEHVLLLCRQQLQELGAGSPGPVTNKATKILRHFEASCGQQLPTLRLCAQPNSAAAPVGPADLLTSPVPAPGSQVFLQPLSSATVVPRSPVLFPSPNTLPPSALEEPSEVRTQLVCSSEQGTESEQRLENTDTPEDSSSPLPWSPNSLFAGMELVACPRLPCHSSQDLQTDLQKVTTEAPVSEPSAFAFLNM", "length": 573 }, "evidence": [ { "id": "A0A8V1ADF7", "url": "https://omabrowser.org/oma/group/A0A8V1ADF7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96N21-1", "protein_name": "AP-4 complex accessory subunit Tepsin", "gene_name": "TEPSIN", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAAPPLRDRLSFLHRLPILLKGTSDDDVPCPGYLFEEIAKISHESPGSSQCLLEYLLSRLHSSSGHGKLKVLKILLYLCSHGSSFFLLILKRNSAFIQEAAAFAGPPDPLHGNSLYQKVRAAAQDLGSTLFSDTVLPLAPSQPLGTPPATGMGSQARPHSTLQGFGYSKEHGRTAVRHQPGQAGGGWDELDSGPSSQNSSQNSDLSRVSDSGSHSGSDSHSGASREPGDLAERVEVVALSDCQQELSLVRTVTRGPRAFLSREEAQHFIKACGLLNCEAVLQLLTCHLRGTSECTQLRALCAIASLGSSDLLPQEHILLRTRPWLQELSMGSPGPVTNKATKILRHFEASCGQLSPARGTSAEPGPTAALPGPSDLLTDAVPLPGSQVFLQPLSSTPVSSRSPAPSSGMPSSPVPTPPPDASPIPAPGDPSEAEARLAESRRWRPERIPGGTDSPKRGPSSCAWSRDSLFAGMELVACPRLVGAGAAAGESCPDAPRAPQTSSQRTAAKEPPGSEPSAFAFLNA", "length": 525 }, "evidence": [ { "id": "A0A8V1ADF7", "url": "https://omabrowser.org/oma/group/A0A8V1ADF7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "trans-Golgi network membrane", "id": "GO:0032588", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032588", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADF7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF7" } ], "pmid": "" }, { "name": "cytoplasmic vesicle", "id": "GO:0031410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031410", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADF7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF7" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADF7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 263, "end_pos": 265, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1ADF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF7" }, { "id": "PF25827", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25827" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "AP-4 complex accessory subunit Tepsin VHS/ENTH-like", "eco_id": "ECO_0000259", "start_pos": 310, "end_pos": 413, "start_aa": "Arg", "end_aa": "Phe", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1ADF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF7" }, { "id": "PF01417", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01417" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "ENTH", "eco_id": "ECO_0000259", "start_pos": 25, "end_pos": 132, "start_aa": "Glu", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 466, 491 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 263, "end_pos": 265 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1ADG7-1", "uniprot_ac": "A0A8V1ADG7", "uniprot_id": "A0A8V1ADG7_CHICK", "mass": { "chemical_mass": 126199.0, "monoisotopic_mass": 126199.0 }, "refseq": {}, "gene_names": [ { "name": "CEP131", "type": "recommended", "evidence": [ { "id": "A0A8V1ADG7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADG7" } ] } ], "protein_names": [ { "name": "Centrosomal protein 131", "type": "synonym", "evidence": [ { "id": "A0A8V1ADG7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADG7/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADG7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADG7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CEP131", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADG7", "locus": { "chromosome": "18", "start_pos": 9908881, "end_pos": 9895448, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029531", "url": "https://www.ensembl.org/id/ENSGALG00010029531" } ] } } ], "crossref": [ { "id": "A0A8V1ADG7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1ADG7", "database": "AlphaFoldDB", "categories": [] }, { "id": "422074", "url": "https://www.ncbi.nlm.nih.gov/gene/422074", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR030465", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030465", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "RKECTLA", "url": "https://omabrowser.org/oma/group/RKECTLA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ADG2", "url": "https://www.orthodb.org/?gene=A0A8V1ADG2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ADG7", "url": "https://www.orthodb.org/?gene=A0A8V1ADG7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AIV0", "url": "https://www.orthodb.org/?gene=A0A8V1AIV0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AIV7", "url": "https://www.orthodb.org/?gene=A0A8V1AIV7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AMJ9", "url": "https://www.orthodb.org/?gene=A0A8V1AMJ9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31540", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31540", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31540:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31540:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF27681", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27681", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF27695", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27695", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-2565942", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2565942", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-380259", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-380259", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-380270", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-380270", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-380284", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-380284", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-380320", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-380320", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5620912", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5620912", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-8854518", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8854518", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1ADG2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADG2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ADG2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADG2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ADG7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADG7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ADG7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADG7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AIV0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIV0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AIV0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIV0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AIV7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIV7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AIV7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIV7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AMJ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMJ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AMJ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMJ9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRSARSSCSCPGGAVELSLTGLPVPVARRPSSASPAKHVVRSVSVVGDGKSKRNALEDAGSRAINNLRRSNSTTQVNQRANGTRSSEQTGDFLTFFESSSGGRKKVASVSKTSLEKKTTWNILDDQPRAFPGPSSSRATEPPAGMRKKEATVLLAANFTANNRSNKGAMGNCVTTMVHNNYSTTDKGPAPKSSNQAPSSLNNVIKATANEDNESSSFMKSQKNFSSNNIMTHNNNSSLPRRREVTEEEAERFIQQVNLAAVTIQRWYRRHSQQRRAGAAALGRLLAAKREERQQQEERNVLDLRDKKDEERRKIREEKARLARRAAIQELHQKRAQKASDTKRLAEEELAQVKESRRVAKKKPAKPASARNGSPASSSIKANNADASFHSVAAEPEASGLAELSPVPAQDRGVEDKLQVVSSRETGGEDLETVVTAVSRAPSKVTLSELLDTLRLLEEEPELLPPPKLFKKDKYTWVDGEPGSNSLTADNLEKFGKLNHSPGVPEDGALLSEAKLQSIISFLDEMEKSEQERPRSATSATQREGLLSEEELAHLEQASAVATEVTSSIMRLKLEVEEKKRAISLLQTALAQQRELTVRHVKQTEKELGHQLQLQREQYEAAIQRHLAFIDQLIDDKKVLSEKCETVVAELKQVDQKYGKKLTQMQEQHELEIKKLKELMSATEKIRREKWIDEKTKKIKEITVKGLEPEIQKLITKHRQDIQKLKMLHEAELLQSDERAAQRYCRQAEELRGLLEQQKEEQSQRERELARQQYVGLVASGWHAEPTHGGCEKQLEQEEQALQQQRRRLYAEVAEEKERLSQQAARQRAEVEELRRQLEASSLAVTTALKEEYAREKEEQERRHQTEVKVLKDRLELEKQAWEASYVKKEEAWLLSRERELREEVRKERDKEIELVIQRLEADMSSAKEECERAAENRIKRIRDKYEVELQELERSERKLQERCNELKGRLVELEGESIRLQGLLKHKEQEVEETRKVRDQLSQERSSLAEVIRQEFADRLVGTEEENRRLKAEMAELRTRQRLELDRVVREKDRELEEVHRRVKTAVARKEENVSSLRKQYEAAVQRADHLEALLEQQRRQLLAAK", "length": 1106, "header": "tr|A0A8V1ADG7-1|A0A8V1ADG7_CHICK Isoform 1 of Centrosomal protein 131 OS=Gallus gallus OX=9031 GN=CEP131 PE=1 SV=1 CANONICAL=A0A8V1ADG7-1" }, "isoforms": [ { "isoform_ac": "A0A8V1ADG2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADG7/entry#A0A8V1ADG2-1", "sequence": { "sequence": "MRSARSSCSCPGGAVELSLTGLPVPVARRPSSASPAKHVVRSVSVVGDGKSKRNALEDAGSRAINNLRRSNSTTQVNQRANGTRSSEQTGDFLTFFESSSGGRKKVASVSKTSLEKKTTWNILDDQPRAFPGPSSSRATEPPAGMRKKEATVLLAANFTANNRSNKGAMGNCVTTMVHNNYSTTDKGPAPKSSNQAPSSLNNVIKATANEDNESSSFMKSQKNFSSNNIMTHNNNSSLPRRREVTEEEAERFIQQVNLAAVTIQRWYRRHSQQRRAGAAALGRLLAAKREERQQQEERNVLDLRDKKDEERRKIREEKARLARRAAIQELHQKRAQKASDTKRLAEEELAQVKESRRVAKKKPAKPASARNGSPASSSIKANNADASFHSVAAEPEASGLAELSPVPAQDRGVEDKLQVVSSRETGGEDLETVVTAVSRAPSKVTLSELLDTLRLLEEEPELLPPPKLFKKDKYTWVDGEPGSNSLTADNLEKFGKLNHSPGVPEDGALLSEAKLQSIISFLDEMEKSEQERPRSATSATQREGLLSEEELAHLEQASAVATEVTSSIMRLKLEVEEKKRAISLLQTALAQQRELTVRHVKQTEKELGHQLQLQREQYEAAIQRHLAFIDQLIDDKKVLSEKCETVVAELKQVDQKYGKKLTQMQEQHELVWRALGPFCEEIKKLKELMSATEKIRREKWIDEKTKKIKEITVKGLEPEIQKLITKHRQDIQKLKMLHEAELLQSDERAAQRYCRQAEELRGLLEQQKEEQSQRERELARQQCEKQLEQEEQALQQQRRRLYAEVAEEKERLSQQAARQRAEVEELRRQLEASSLAVTTALKEEYAREKEEQERRHQTEVKVLKDRLELEKQAWEASYVKKEEAWLLSRERELREEVRKERDKEIELVIQRLEADMSSAKEECERAAENRIKRIRDKYEVELQELERSERKLQERCNELKGRLVELEGESIRLQGLLKHKEQEVEETRKVRDQLSQERSSLAEVIRQEFADRLVGTEEENRRLKAEMAELRTRQRLELDRVVREKDRELEEVHRRVKTAVARKEENVSSLRKQYEAAVQRADHLEALLEQQRRQLLAAK", "length": 1099, "header": "tr|A0A8V1ADG2-1|A0A8V1ADG7_CHICK Computationally mapped isoform of Centrosomal protein 131 OS=Gallus gallus OX=9031 GN=CEP131 PE=1 SV=1 CANONICAL=A0A8V1ADG7-1" }, "locus": { "chromosome": "18", "start_pos": 9907551, "end_pos": 9895562, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071380.1", "url": "https://www.ensembl.org/id/ENSGALT00010071380.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044070.1", "url": "https://www.ensembl.org/id/ENSGALP00010044070.1" } ] } }, { "isoform_ac": "A0A8V1ADG7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADG7/entry#A0A8V1ADG7-1", "sequence": { "sequence": "MRSARSSCSCPGGAVELSLTGLPVPVARRPSSASPAKHVVRSVSVVGDGKSKRNALEDAGSRAINNLRRSNSTTQVNQRANGTRSSEQTGDFLTFFESSSGGRKKVASVSKTSLEKKTTWNILDDQPRAFPGPSSSRATEPPAGMRKKEATVLLAANFTANNRSNKGAMGNCVTTMVHNNYSTTDKGPAPKSSNQAPSSLNNVIKATANEDNESSSFMKSQKNFSSNNIMTHNNNSSLPRRREVTEEEAERFIQQVNLAAVTIQRWYRRHSQQRRAGAAALGRLLAAKREERQQQEERNVLDLRDKKDEERRKIREEKARLARRAAIQELHQKRAQKASDTKRLAEEELAQVKESRRVAKKKPAKPASARNGSPASSSIKANNADASFHSVAAEPEASGLAELSPVPAQDRGVEDKLQVVSSRETGGEDLETVVTAVSRAPSKVTLSELLDTLRLLEEEPELLPPPKLFKKDKYTWVDGEPGSNSLTADNLEKFGKLNHSPGVPEDGALLSEAKLQSIISFLDEMEKSEQERPRSATSATQREGLLSEEELAHLEQASAVATEVTSSIMRLKLEVEEKKRAISLLQTALAQQRELTVRHVKQTEKELGHQLQLQREQYEAAIQRHLAFIDQLIDDKKVLSEKCETVVAELKQVDQKYGKKLTQMQEQHELEIKKLKELMSATEKIRREKWIDEKTKKIKEITVKGLEPEIQKLITKHRQDIQKLKMLHEAELLQSDERAAQRYCRQAEELRGLLEQQKEEQSQRERELARQQYVGLVASGWHAEPTHGGCEKQLEQEEQALQQQRRRLYAEVAEEKERLSQQAARQRAEVEELRRQLEASSLAVTTALKEEYAREKEEQERRHQTEVKVLKDRLELEKQAWEASYVKKEEAWLLSRERELREEVRKERDKEIELVIQRLEADMSSAKEECERAAENRIKRIRDKYEVELQELERSERKLQERCNELKGRLVELEGESIRLQGLLKHKEQEVEETRKVRDQLSQERSSLAEVIRQEFADRLVGTEEENRRLKAEMAELRTRQRLELDRVVREKDRELEEVHRRVKTAVARKEENVSSLRKQYEAAVQRADHLEALLEQQRRQLLAAK", "length": 1106, "header": "tr|A0A8V1ADG7-1|A0A8V1ADG7_CHICK Isoform 1 of Centrosomal protein 131 OS=Gallus gallus OX=9031 GN=CEP131 PE=1 SV=1 CANONICAL=A0A8V1ADG7-1" }, "locus": { "chromosome": "18", "start_pos": 9907551, "end_pos": 9895562, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071385.1", "url": "https://www.ensembl.org/id/ENSGALT00010071385.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044075.1", "url": "https://www.ensembl.org/id/ENSGALP00010044075.1" } ] } }, { "isoform_ac": "A0A8V1AIV0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADG7/entry#A0A8V1AIV0-1", "sequence": { "sequence": "MRSARSSCSCPGGAVELSLTGLPVPVARRPSSASPAKHVVRSVSVVGDGKSKRNALEDAGSRAINNLRRSNSTTQVNQRANGTRSSRATEPPAGMRKKEATVLLAANFTANNRSNKGAMGNCVTTMVHNNYSTTDKGPAPKSSNQAPSSLNNVIKATANEDNESSSFMKSQKNFSSNNIMTHNNNSSLPRRREVTEEEAERFIQQVNLAAVTIQRWYRRHSQQRRAGAAALGRLLAAKREERQQQEERNVLDLRDKKDEERRKIREEKARLARRAAIQELHQKRAQKASDTKRLAEEELAQVKESRRVAKKKPAKPASARNGSPASSSIKANNADASFHSVAAEPEASGLAELSPVPAQDRGVEDKLQVVSSRETGGEDLETVVTAVSRAPSKVTLSELLDTLRLLEEEPELLPPPKLFKKDKYTWVDGEPGSNSLTADNLEKFGKLNHSPGVPEDGALLSEAKLQSIISFLDEMEKSEQERPRSATSATQREGLLSEEELAHLEQASAVATEVTSSIMRLKLEVEEKKRAISLLQTALAQQRELTVRHVKQTEKELGHQLQLQREQYEAAIQRHLAFIDQLIDDKKVLSEKCETVVAELKQVDQKYGKKLTQMQEQHELEIKKLKELMSATEKIRREKWIDEKTKKIKEITVKGLEPEIQKLITKHRQDIQKLKMLHEAELLQSDERAAQRYCRQAEELRGLLEQQKEEQSQRERELARQQCEKQLEQEEQALQQQRRRLYAEVAEEKERLSQQAARQRAEVEELRRQLEASSLAVTTALKEEYAREKEEQERRHQTEVKVLKDRLELEKQAWEASYVKKEEAWLLSRERELREEVRKERDKEIELVIQRLEADMSSAKEECERAAENRIKRIRDKYEVELQELERSERKLQERCNELKGRLVELEGESIRLQGLLKHKEQEVEETRKVRDQLSQERSSLAEVIRQEFADRLVGTEEENRRLKAEMAELRTRQRLELDRVVREKDRELEEVHRRVKTAVARKEENVSSLRKQYEAAVQRADHLEALLEQQRRQLLAAK", "length": 1039, "header": "tr|A0A8V1AIV0-1|A0A8V1ADG7_CHICK Computationally mapped isoform of Centrosomal protein 131 OS=Gallus gallus OX=9031 GN=CEP131 PE=1 SV=1 CANONICAL=A0A8V1ADG7-1" }, "locus": { "chromosome": "18", "start_pos": 9907551, "end_pos": 9895562, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071377.1", "url": "https://www.ensembl.org/id/ENSGALT00010071377.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044067.1", "url": "https://www.ensembl.org/id/ENSGALP00010044067.1" } ] } }, { "isoform_ac": "A0A8V1AIV7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADG7/entry#A0A8V1AIV7-1", "sequence": { "sequence": "MRSARSSCSCPGGAVELSLTGLPVPVARRPSSASPAKHVVRSVSVVGDGKSKRNALEDAGSRAINNLRRSNSTTQVNQRANGTRSSEQTGDFLTFFESSSGGRKKVASVSKTSLEKKTTWNILDDQPRAFPGPSSSRATEPPAGMRKKEATVLLAANFTANNRSNKGAMGNCVTTMVHNNYSTTDKGPAPKSSNQAPSSLNNVIKATANEDNESSSFMKSQKNFSSNNIMTHNNNSSLPRRREVTEEEAERFIQQVNLAAVTIQRWYRRHSQQRRAGAAALGRLLAAKREERQQQEERNVLDLRDKKDEERRKIREEKARLARRAAIQELHQKRAQKASDTKRLAEEELAQVKESRRVAKKKPAKPASARNGSPASSSIKANNADASFHSVAAEPEASGLAELSPVPAQDRGVEDKLQVVSSRETGGEDLETVVTAVSRAPSKVTLSELLDTLRLLEEEPELLPPPKLFKKDKYTWVDGGLLSEEELAHLEQASAVATEVTSSIMRLKLEVEEKKRAISLLQTALAQQRELTVRHVKQTEKELGHQLQLQREQYEAAIQRHLAFIDQLIDDKKVLSEKCETVVAELKQVDQKYGKKLTQMQEQHELEIKKLKELMSATEKIRREKWIDEKTKKIKEITVKGLEPEIQKLITKHRQDIQKLKMLHEAELLQSDERAAQRYCRQAEELRGLLEQQKEEQSQRERELARQQCEKQLEQEEQALQQQRRRLYAEVAEEKERLSQQAARQRAEVEELRRQLEASSLAVTTALKEEYAREKEEQERRHQTEVKVLKDRLELEKQAWEASYVKKEEAWLLSRERELREEVRKERDKEIELVIQRLEADMSSAKEECERAAENRIKRIRDKYEVELQELERSERKLQERCNELKGRLVELEGESIRLQGLLKHKEQEVEETRKVRDQLSQERSSLAEVIRQEFADRLVGTEEENRRLKAEMAELRTRQRLELDRVVREKDRELEEVHRRVKTAVARKEENVSSLRKQYEAAVQRADHLEALLEQQRRQLLAAK", "length": 1025, "header": "tr|A0A8V1AIV7-1|A0A8V1ADG7_CHICK Computationally mapped isoform of Centrosomal protein 131 OS=Gallus gallus OX=9031 GN=CEP131 PE=1 SV=1 CANONICAL=A0A8V1ADG7-1" }, "locus": { "chromosome": "18", "start_pos": 9907551, "end_pos": 9895562, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071382.1", "url": "https://www.ensembl.org/id/ENSGALT00010071382.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044072.1", "url": "https://www.ensembl.org/id/ENSGALP00010044072.1" } ] } }, { "isoform_ac": "A0A8V1AMJ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADG7/entry#A0A8V1AMJ9-1", "sequence": { "sequence": "MRSARSSCSCPGGAVELSLTGLPVPVARRPSSASPAKHVVRSVSVVGDGKSKRNALEDAGSRAINNLRRSNSTTQVNQRANGTRSSEQTGDFLTFFESSSGGRKKVASVSKTSLEKKTTWNILDDQPRAFPGPSSSRATEPPAGMRKKEATVLLAANFTANNRSNKGAMGNCVTTMVHNNYSTTDKGPAPKSSNQAPSSLNNVIKATANEDNESSSFMKSQKNFSSNNIMTHNNNSSLPRRREVTEEEAERFIQQVNLAAVTIQRWYRRHSQQRRAGAAALGRLLAAKREERQQQEERNVLDLRDKKDEERRKIREEKARLARRAAIQELHQKRAQKASDTKRLAEEELAQVKESRRVAKKKPAKPASARNGSPASSSIKANNADASFHSVAAEPEASGLAELSPVPAQDRGVEDKLQVVSSRETGGEDLETVVTAVSRAPSKVTLSELLDTLRLLEEEPELLPPPKLFKKDKYTWVDGEPGSNSLTADNLEKFGKLNHSPGVPEDGALLSEAKLQSIISFLDEMEKSEQERPRSATSATQREGLLSEEELAHLEQASAVATEVTSSIMRLKLEVEEKKRAISLLQTALAQQRELTVRHVKQTEKELGHQLQLQREQYEAAIQRHLAFIDQLIDDKKVLSEKCETVVAELKQVDQKYGKKLTQMQEQHELEIKKLKELMSATEKIRREKWIDEKTKKIKEITVKGLEPEIQKLITKHRQDIQKLKMLHEAELLQSDERAAQRYCRQAEELRGLLEQQKEEQSQRERELARQQCEKQLEQEEQALQQQRRRLYAEVAEEKERLSQQAARQRAEVEELRRQLEASSLAVTTALKEEYAREKEEQERRHQTEVKVLKDRLELEKQAWEASYVKKEEAWLLSRERELREEVRKERDKEIELVIQRLEADMSSAKEECERAAENRIKRIRDKYEVELQELERSERKLQERCNELKGRLVELEGESIRLQGLLKHKEQEVEETRKVRDQLSQERSSLAEVIRQEFADRLVGTEEENRRLKAEMAELRTRQRLELDRVVREKDRELEEVHRRVKTAVARKEENVSSLRKQYECFHSLDMGAQ", "length": 1075, "header": "tr|A0A8V1AMJ9-1|A0A8V1ADG7_CHICK Computationally mapped isoform of Centrosomal protein 131 OS=Gallus gallus OX=9031 GN=CEP131 PE=1 SV=1 CANONICAL=A0A8V1ADG7-1" }, "locus": { "chromosome": "18", "start_pos": 9908634, "end_pos": 9895562, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071388.1", "url": "https://www.ensembl.org/id/ENSGALT00010071388.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044078.1", "url": "https://www.ensembl.org/id/ENSGALP00010044078.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-2565942", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2565942", "resource": "Reactome", "description": "Regulation of PLK1 Activity at G2/M Transition" }, { "id": "R-GGA-380259", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-380259", "resource": "Reactome", "description": "Loss of Nlp from mitotic centrosomes" }, { "id": "R-GGA-380270", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-380270", "resource": "Reactome", "description": "Recruitment of mitotic centrosome proteins and complexes" }, { "id": "R-GGA-380284", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-380284", "resource": "Reactome", "description": "Loss of proteins required for interphase microtubule organization from the centrosome" }, { "id": "R-GGA-380320", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-380320", "resource": "Reactome", "description": "Recruitment of NuMA to mitotic centrosomes" }, { "id": "R-GGA-5620912", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5620912", "resource": "Reactome", "description": "Anchoring of the basal body to the plasma membrane" }, { "id": "R-GGA-8854518", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8854518", "resource": "Reactome", "description": "AURKA Activation by TPX2" } ], "orthologs": [ { "uniprot_canonical_ac": "D4AEL8-1", "protein_name": "Centrosomal protein 131", "gene_name": "Cep131", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKGSRTISATPEGSPEGMDLSLIGLPLPMSQRPGSASAAKSIFRSVSVATGSEPRKKALEATGPGGPRAINNLRRSNSTTQVNQSWTGSPRPAEPTDFLMLFEGSTSGRRRVASFSKVSSEKGATWNVLDDQPRDFASPANSQSPSTLDSALGPRRKECSLAPSFTANNSNIVKAAAREGGEGSDFGKPRKNFSSVSQSTRGTTGLLRRKEVTEEEAERFIQQVNQAAVTIQRWYRCQVQRRRTGAASLEHLLASKREGQRQRLGSGNLLDLHRQEEAARKKAREEKARQARQAAIQELQQKRAQKAREVEHRPPKERPETRALEQPRPTQEPPSMPSSVTHPKANNAGASLYPTGPADPCPPASESFPERQPSLEDKPQDAHSQVEAREDLAALASTRSKTRARATLDDLLDTLKLLEEEPEPLLHPKAYRQDRYAWMDEEEDTNPLTADNLEKFGKLSAAPGPPDDGTLLSEAKLQSIMTFLDEMEKSGQERPAPWRESLVLEAGPRSLELGSEGTTSVMRLKLELEEKKQAMVLLQRALAQQRDLATRRVKETEKELSRQLRQQKEQYEATIQRHLSFIDQLIEDKKVLSEKCEAVVAELKQGDQRCRERVAQVQEQHELEIKKLKELMSATEKIRREKWINEKTKKIKEITVRGLEPEIQKLIAKHKQEVRRLRGLHEAELQQREEQAAQRHLRQAEELREHLEREREALGQQERERAQQRLEQHLEQEQRALEQQRRRLYTEVAEEKERLGQQAARQRVELEELRQQLEESSAALTRALRAEFERSREEQERRHQMELKALKDQLEAERQAWVASCAKKEEAWLLTRERELKEEIRKGRDQEIELVIHRLEADMTLAKEESERAAENRVKRVRDKYETELSELEQSERKLQERCTELKGRLGEAEGEKERLQSLLRQKEKELDDLRVVNTQMCSERASLAQVVRQEFAEQLAASQEETQRVKAELAELRARQQMELDEVHRRVKTALARKEAAVNSLRKQHEAAEKRADHLEELLEQHKGPSLSSK", "length": 1031 }, "evidence": [ { "id": "A0A8V1ADG7", "url": "https://omabrowser.org/oma/group/A0A8V1ADG7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q62036-1", "protein_name": "Centrosomal protein of 131 kDa", "gene_name": "Cep131", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGSRTITATPEGSPEAVDLSLIGLPPPMSQRPGSASATRSIFRSMSVATGSEPRKKALEATGPGGPRAINNLRRSNSTTQVNQSWTGSPRPAEPTDFLMLFEGSTSGRRRVASLSKASSEKEATWNVLDEQPRGLALPASAQSPSTLDSALGPRRKECPLAPSFTANNRSNKGAVGNCVTTMVHNHYASSKMVSPPKSSNQTAPSLNNIVKAAAREGGEGSDLGKPRKNLSSASQSARGTTGLLRRREVTEEEAERFIHQVNQAAVTIQRWYRCQVQRRRAGAAALEHLLASKREGQRQRLGGGNLLELHRQEEAARKKAREEKARQARQAAIQVLQQKRAQKASEAEHRRPKDRPETRAPEQPRPMQEPGCVTHPKANNAGASIYPTGPADPCPPASESSPEQWQSPEDKPQDIHSQGEARQDLAVSGSSRGKARARATLDDLLDTLKLLEEEPEPLPHPKAYHKDRYAWTDEEEDANSLTADNLEKFGKLSAAPGPPDDGTLLSEAKLQSIMTFLDEMEKSGQERPAPWRESLVLEAGSGSEGSTSVMRLKLELEEKKQAMALLQRALAQQRDLTVRRVKETEKELTRQLRQQKEQYEATIQRHLSFIDQLIEDKKVLSEKCEAVVAELKHGDQRCRERVAQMQEQHELEIKKLKELMSATEKIRREKWINEKTKKIKEITVRGLEPEIQKLIAKHKQEVRRLRGLHEAELQQREEQAAQRHLRQAEELRQHLDREREVLGQQERERAQQRFEQHLEQEQRALEQQRRRLYNEVAEEKERLGQQAARQRAELEELRQQLEESSAALTRALRAEFERSREEQERRHQMELKALKDQLEAERQAWVASCAKKEEAWLLTRERELKEEIRKGRDQEIELVIHRLEADMTLAKEESERAAESRVKRVRDKYETELSELEQSERKLQERCSELKGRLGEAEGEKERLQSLVRQKEKELEDLRAVNTQMCSERASLAQVVRQEFAEQLAASQEETQRVKVELAELQARQQVELDEVHRRVKTALARKEAAVNSLRKQHEAAVKRADHLEELLEQHKGSSLSSK", "length": 1060 }, "evidence": [ { "id": "A0A8V1ADG7", "url": "https://omabrowser.org/oma/group/A0A8V1ADG7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9UPN4-1", "protein_name": "Centrosomal protein of 131 kDa", "gene_name": "CEP131", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKGTRAIGSVPERSPAGVDLSLTGLPPPVSRRPGSAATTKPIVRSVSVVTGSEQKRKVLEATGPGGSQAINNLRRSNSTTQVSQPRSGSPRPTEPTDFLMLFEGSPSGKKRPASLSTAPSEKGATWNVLDDQPRGFTLPSNARSSSALDSPAGPRRKECTVALAPNFTANNRSNKGAVGNCVTTMVHNRYTPSERAPPLKSSNQTAPSLNNIIKAATCEGSESSGFGKLPKNVSSATHSARNNTGGSTGLPRRKEVTEEEAERFIHQVNQATVTIQRWYRHQVQRRGAGAARLEHLLQAKREEQRQRSGEGTLLDLHQQKEAARRKAREEKARQARRAAIQELQQKRALRAQKASTAERGPPENPRETRVPGMRQPAQELSPTPGGTAHQALKANNTGGGLPAAGPGDRCLPTSDSSPEPQQPPEDRTQDVLAQDAAGDNLEMMAPSRGSAKSRGPLEELLHTLQLLEKEPDVLPRPRTHHRGRYAWASEVTTEDDASSLTADNLEKFGKLSAFPEPPEDGTLLSEAKLQSIMSFLDEMEKSGQDQLDSQQEGWVPEAGPGPLELGSEVSTSVMRLKLEVEEKKQAMLLLQRALAQQRDLTARRVKETEKALSRQLQRQREHYEATIQRHLAFIDQLIEDKKVLSEKCEAVVAELKQEDQRCTERVAQAQAQHELEIKKLKELMSATEKARREKWISEKTKKIKEVTVRGLEPEIQKLIARHKQEVRRLKSLHEAELLQSDERASQRCLRQAEELREQLEREKEALGQQERERARQRFQQHLEQEQWALQQQRQRLYSEVAEERERLGQQAARQRAELEELRQQLEESSSALTRALRAEFEKGREEQERRHQMELNTLKQQLELERQAWEAGRTRKEEAWLLNREQELREEIRKGRDKEIELVIHRLEADMALAKEESEKAAESRIKRLRDKYEAELSELEQSERKLQERCSELKGQLGEAEGENLRLQGLVRQKERALEDAQAVNEQLSSERSNLAQVIRQEFEDRLAASEEETRQAKAELATLQARQQLELEEVHRRVKTALARKEEAVSSLRTQHEAAVKRADHLEELLEQHRRPTPSTK", "length": 1083 }, "evidence": [ { "id": "A0A8V1ADG7", "url": "https://omabrowser.org/oma/group/A0A8V1ADG7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "U3JAG9-1", "protein_name": "Centrosomal protein of 131 kDa", "gene_name": "cep131", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1ADH4-1", "uniprot_ac": "A0A8V1ADH4", "uniprot_id": "A0A8V1ADH4_CHICK", "mass": { "chemical_mass": 37512.0, "monoisotopic_mass": 37512.0 }, "refseq": { "ac": "XP_040504069", "name": "radial spoke head 14 homolog isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040504069" }, "gene_names": [ { "name": "RSPH14", "type": "recommended", "evidence": [ { "id": "A0A8V1ADH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADH4" } ] }, { "name": "RSPH14", "type": "synonym", "evidence": [ { "id": "XP_040504069", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040504069" } ] } ], "protein_names": [ { "name": "Radial spoke head 14 homolog", "type": "synonym", "evidence": [ { "id": "A0A8V1ADH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADH4/entry#names_and_taxonomy" } ] }, { "name": "radial spoke head 14 homolog isoform X1", "type": "synonym", "evidence": [ { "id": "XP_040504069", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040504069" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052546.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040504069", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040504069" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADH4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADH4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RSPH14", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADH4", "locus": { "chromosome": "15", "start_pos": 8770424, "end_pos": 8697719, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010026565", "url": "https://www.ensembl.org/id/ENSGALG00010026565" } ] } } ], "crossref": [ { "id": "A0A8V1ADH4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1ADH4", "database": "AlphaFoldDB", "categories": [] }, { "id": "416954", "url": "https://www.ncbi.nlm.nih.gov/gene/416954", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000225", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000225", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021133", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021133", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042856", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042856", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416954", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416954", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VWQHDVI", "url": "https://omabrowser.org/oma/group/VWQHDVI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ADH4", "url": "https://www.orthodb.org/?gene=A0A8V1ADH4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15599", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15599", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15599:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15599:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00514", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00514", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13646", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13646", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040504069", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040504069", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1ADH4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADH4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ADH4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADH4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASTLISAKLPPDVDPTKAPIAFGRRALPKLSREIQSPELLTQQRALMALCDLVHDPENVYQAVQIGFLENLKTLLLHHDSTVRQKTTEILYIMAMHNVGRQGLIQNAVIPVLTELLDDPEDICRKNTHQVLDMMAKLPEGAVDILHAGLIPLLVVRLKTESDEIQELILGTLSNCLRMEASEALATDAITILKEKLTHPSATIRNKAAQVILEIGTHPEGKSTVCEEVIPLLVSLLEDTDPEVQASAAGALMFATIKPKGRCLALRAEAIPRLLKLVAVENSKARLSAIKTLTMLAEVAEGRRKLLERTDIFQQCLRDPSEAVKRAAEIAIRVIRWKPF", "length": 340, "header": "tr|A0A8V1ADH4-1|A0A8V1ADH4_CHICK Isoform 1 of Radial spoke head 14 homolog OS=Gallus gallus OX=9031 GN=RSPH14 PE=4 SV=1 CANONICAL=A0A8V1ADH4-1" }, "isoforms": [ { "isoform_ac": "A0A8V1ADH4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADH4/entry#A0A8V1ADH4-1", "sequence": { "sequence": "MASTLISAKLPPDVDPTKAPIAFGRRALPKLSREIQSPELLTQQRALMALCDLVHDPENVYQAVQIGFLENLKTLLLHHDSTVRQKTTEILYIMAMHNVGRQGLIQNAVIPVLTELLDDPEDICRKNTHQVLDMMAKLPEGAVDILHAGLIPLLVVRLKTESDEIQELILGTLSNCLRMEASEALATDAITILKEKLTHPSATIRNKAAQVILEIGTHPEGKSTVCEEVIPLLVSLLEDTDPEVQASAAGALMFATIKPKGRCLALRAEAIPRLLKLVAVENSKARLSAIKTLTMLAEVAEGRRKLLERTDIFQQCLRDPSEAVKRAAEIAIRVIRWKPF", "length": 340, "header": "tr|A0A8V1ADH4-1|A0A8V1ADH4_CHICK Isoform 1 of Radial spoke head 14 homolog OS=Gallus gallus OX=9031 GN=RSPH14 PE=4 SV=1 CANONICAL=A0A8V1ADH4-1" }, "locus": { "chromosome": "15", "start_pos": 8767304, "end_pos": 8698385, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010064533.1", "url": "https://www.ensembl.org/id/ENSGALT00010064533.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039558.1", "url": "https://www.ensembl.org/id/ENSGALP00010039558.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:416954", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416954", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2K0V7-1", "protein_name": "Radial spoke head 14 homolog", "gene_name": "Rsph14", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRKRSWFTSCSKRLMEALQRSSSCSMSPTERSSMRGGSESGNCALQASAKPTESTMARPAHLRRGAARRSPAQRRRGVLTVPGPGRPAPPMIPRLRRRTMPAPRGRSFYKVSSSKPVGRRGKMAHARISMYMPPDIDPTKAAIAYGCRALRKLNEELQSEDLLTRQKAVMALCDLMHDPEYVYEAINIGCLESLKALLKDDDNLVRIKTTEVLYIMATHNVGRVGFLKHDIILALSRLLSDHQTLCRENLHQAYKHLAQLPEGAQGIVTSGLISFLVRKLQKEELHIQEIILDTLALCLQEDATEALNSQAVPCFKEKLFSGNPQIRSKAARALIAISIPLDGKRQVWQNEVIPILVDLLSDTDEEVKANAAGALMHATVTTEGKYAALDANAIDPLLELLCSIPTTKVCLNATKALTMLAEAPEGRKLLLPRVPTFRYLLTHKNEAIRRAAEVAIKVIEWKP", "length": 463 }, "evidence": [ { "id": "A0A8V1ADH4", "url": "https://omabrowser.org/oma/group/A0A8V1ADH4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8M1P3V2-1", "protein_name": "Radial spoke head 14 homolog", "gene_name": "rsph14", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MASPQTTEQPPPHIDPTQAPIAFGNLALPKLLVELQDDDLFTRQKALTALCDLLHDPERAYEAIFSECLEILKVLLQDEDSLIRVKTTEVLYVLASHSMGRDAFLNFDIVGPLANLLDDPEIACRKNVHRALNRIAEFPLGAVFMVNKGLVPRLVPKISIEEENIRALVLSTLSCCLSVNALPALESDVIQVLRDQLSHSSPIIRKEAASALMAISVPTVGKIKVCEENLLPILVKLLSDDDQEVVANAAGTIMNTAVITKGKSEALEADALAPLLQLVLSENTAVCANALRALTVLAEVPRARAHLRQHVPLLKTRLTDPNYLIQEAASTTIEVISWQP", "length": 340 }, "evidence": [ { "id": "A0A8V1ADH4", "url": "https://omabrowser.org/oma/group/A0A8V1ADH4/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0ABI0P4H8-1", "protein_name": "Radial spoke head 14 homolog", "gene_name": "RSPH14", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MADAKISMYLPPNVNPTQAAIAYGCRALPKLNEELQSDDLLTRQKALMALCDLMHDPEHVYTAISIGCLESLKALLKDTNDLVRIKTTEVLCIMATHNVGREGFLEHNVIQALSFLMSDAQPACRENLYTAFKHLAQLPAGALGIVNSGLIPSLVWKLQREEEEIQVLLLDTLAACLTEDATEALASRAVPFLKEKLLSTNCNIRSKAARTLIAVSVPPEGKIQVWQHDVIPILVHLLKDRDEEVQANAAGALMNATVTTEGKYAALDAEATRPLLQLLTSSLSKARLNAIKALTMLAEAPEGRKLLQPHVATFRALEEDFSPAVQRAAQIAIRVIEWKP", "length": 340 }, "evidence": [ { "id": "A0A8V1ADH4", "url": "https://omabrowser.org/oma/group/A0A8V1ADH4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1RLS7-1", "protein_name": "Radial spoke head 14 homolog", "gene_name": "RSPH14", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MADARISMYLPPDINPTQAAIAYGCRALPKLNEELQSEDLVTRQKALMALCGLMHDPEHVYMAIHIGCLENLKALLKDTNDMVRIKTTEVLYIMATHNVGRVGFLEHDVIRALSFLLNDPQSLCRENLHLAFKHLAQLPTGAQGIVSSGLIPSLVWKLQREEEGVQELLLDTLAACLMEDATEALASRAVPFLKEKLLSANSNIRSKAAGTLIAISIPLEGKNQVWKHDVIPILVHLLRDKVAEVQANVAGALMNATVTTEGKYAALNAEAIHPLLQLLCSSLSKARLNAIKALTMLAEAPEGRKLLQAHVPTFRALEKDTSAAVKQAAQIAIKVIEWKP", "length": 340 }, "evidence": [ { "id": "A0A8V1ADH4", "url": "https://omabrowser.org/oma/group/A0A8V1ADH4/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3HMY6-1", "protein_name": "Radial spoke head 14 homolog", "gene_name": "Rsph14", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAHARISMYMPPDIDPTKAAIAYGCRALPKLNEELQSEVLLTRQKALVALCDLMHDPEHVYEAIHIGCLESLKVLLKDEDNLVRIKTTEVLHIMATHNIGRTGLLEKGVILALALLLSDHQKVCRENLHQAYKHVAQTPEGARGITSSGLIPWLVNKLNAEEEHIQEIILDTLAPCLQEDATQALESQAVPYFKKKLLNDNPRIRSKAARALIAISIPLEGKNQVWQNGVIPILVDLLSDVDEEVQANAAGALMHATVTTEGKYAALDASAINPLLELLCSSPIKVCLNAAKALTMLAEAPEGRKLLSSHVSTFRVLLMHENEAIRRAAQVAIKVIEWKP", "length": 340 }, "evidence": [ { "id": "A0A8V1ADH4", "url": "https://omabrowser.org/oma/group/A0A8V1ADH4/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q9D3W1-1", "protein_name": "Radial spoke head 14 homolog", "gene_name": "Rsph14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAHARISMYMPPDIDPTKAAIAYGCRALSKLNEELQSRDLLTRQKALVALCDLMHDPEYVYEAINIGCLESLKTLLQDDDNLVRIKTTEVLYIMATHYVGRVGFLKHDIIQALSLLLSDHQTLCRENLHQAYKHLAQLPKGAQGIVQSGLIPSLVRKLQKEEDHIQEIILDTLALCLQEDATEALESQAVPCLKEKLLSQNSEIRSKAARALIAISIPLDGKNQVWKNKVIPILVTLLSDTDEEVKANAAGALMHATVTTEGKYAALDANAIEPLLELLSTNPKTKLCLNATKALTMLAEAPEGRKLLLSHVPIFRYLLAHKNEAIQRAAEVAIKVIEWKP", "length": 341 }, "evidence": [ { "id": "A0A8V1ADH4", "url": "https://omabrowser.org/oma/group/A0A8V1ADH4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9UHP6-1", "protein_name": "Radial spoke head 14 homolog", "gene_name": "RSPH14", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAHSQNSLELPININATQITTAYGHRALPKLKEELQSEDLQTRQKALMALCDLMHDPECIYKAMNIGCMENLKALLKDSNSMVRIKTTEVLHITASHSVGRYAFLEHDIVLALSFLLNDPSPVCRGNLYKAYMQLVQVPRGAQEIISKGLISSLVWKLQVEVEEEEFQEFILDTLVLCLQEDATEALGSNVVLVLKQKLLSANQNIRSKAARALLNVSISREGKKQVCHFDVIPILVHLLKDPVEHVKSNAAGALMFATVITEGKYAALEAQAIGLLLELLHSPMTIARLNATKALTMLAEAPEGRKALQTHVPTFRAMEVETYEKPQVAEALQRAARIAISVIEFKP", "length": 348 }, "evidence": [ { "id": "A0A8V1ADH4", "url": "https://omabrowser.org/oma/group/A0A8V1ADH4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "radial spoke", "id": "GO:0001534", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001534", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADH4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADH4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": 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Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. 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"categories": [ "Protein" ] }, { "id": "A0A8V1ADH8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADH8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AIW7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIW7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AIW7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIW7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AKP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKP1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AKP1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKP1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AMK4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AMK4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAHKPVEWVQAVVNRFDEQLPIKASQQNTHTKVSTEHNKECLINISKYKFSLVISGLTNILKNVNNMRIFGETAEKNLYLSQLIILDTLEKCLAGQPKDTMRLDETMLVKQLLPEICHFIHTYREGNQHAAELRNSASGVLFSLSCNNFNAVFSRISTRLQELTVCSEDNADVHDIELLQYISVDCSKLKRLLQETVFKFKALKKVAQLAVINSLEKAFWNWVENYPDEFTKLYQTPQTDMADCAEKLFDLVDGFAESTKRKAAVWPLQIILLVLCPEIIQDIAKDVVEETKMNKKLFLDNLRKALAGHSGSRQLTESAAIACVKLCKASTYINWEDNSVIFLLVQSMVVDLKNLLFNPSKPFSRSNQNADVDLMIDCLVSCFRINPHNNQHFKICLAQSSPSTFHYVLVNSLHRIITNSALDWWPRIDAVYCHSVELRSMFSETLHKAIQGCGAHPAIRMTPSLTFKEKMTSLKFKEKPTDLETKSYKFLLLSLVKLIHADPKLLLCNPRKQGPETQGSTAELITGLVQLVPQSSMPDIAQEAMEALLVLHQLDSIDLWNPDAPIETFWEISSQMLFYICKKLTSHQMLSSTEILKWLREILICRNKFLLKNKQSDRTSCHFLFLYDVSGGGASQMSLDHEEMMRCAPGATLRKGKGNSSMESTAGCSGTPICRQAQTKLEVALYMFLWSPDIEAVLVAMSCFRHLCEEADIRCGVDEVSVHNFLPNYNTFMEFASVSNMMSTGRAALQKRVMALLRRIEHPTAGNTEAWEDTHAKWEQATKLILNYPKTKMEDGQVTESLHKTIVKRRMSHVSGGGSIDLSDTDSLQEWINMTGFLCALGGVCLQHRSNAGLATYSPPMGPVNERKGSMISMVSTEGNAETPVSKFIDRLLTLMVCNHEKVGLQIRTNIKDLVGLELSPALYPMLFNKLKNTISKFFDSQGQVLLTETNTQFVEQTIAIMKNLLDNHTEGSSEHLGQASIETMMLNLVRYVRVLGNLVHAIQIKTKLCQLVEVMMERRDDLSFCQEMKFRNKMVEYLTDWVMGTSNQATDEDVKCLTRDLDQASMEAVVSLLAGLPLQPEEGDGVELMEAKSQLFLKYFTLFMNLLNDCSEVEDESAQTGGRKRGMSRRLASLRHCTVLAMSNLLNANVDSGLMHSIGLGYHKDLQTRATFMEVLTKILQQGTEFDTLAETVLADRFERLVELVTMMGDQGELPIAMALANVVPCSQWDELARVLVTLFDSRHLLYQLLWNMFSKEVELADSMQTLFRGNSLASKIMTFCFKVYGATYLQKLLEPLLRTVITSSEWQHVSFEVDPTRLEPTESLEENQRSLLQMTEKFFHAIINSSSEFPPQLRSVCHCLYQATCHSLLNKATVKEKKENKKSVVSQRFPQNSIGAVGSAMFLRFINPAIVSPYEAGILDKKPPPRIERGLKLMSKILQSIANHVLFTKEEHMRPFNDFVKSNFDAARRFFLDIASDCPASDTVNHSLSFISDGNVLALHRLLWNNQEKIGQYLSSNRDHKAVGRRPFDKMATLLAYLGPPEHKPVADTHWSSLNLTSSKFEEFMTRHQVHEKEEFKALKTLNIFYQAGTSKAGNPVFYYIARRFKTGQINGDLLIYHVLLTLKPYYAKPYEIVVDLTHAGPSNRFKTDFLSKWFVVFPGFAYENVSAVFIYNCNSWVREYTKYHERLLTGLKGSKRLIFIDSPGKLAEHIEHDQQKLPAATLALEEDLKVFHNALKLAHKDTKVSIKVGSTAVQVTSAERTRVLGQTVFLNDIYYASEIEEICLVDENQFTLTIANQGTPLTFMHQECEAIVRSIIHIRTRWELSQPDSIPQHTKIRPKDVPGTLLNIALLNLGSSDPSLRSAAYNLLCALTCTFNLKIEGQLLETSGLCIPANNTLFIVSISKTLAANEPHLTLEFLEECISGFSKSSIELKHLCLEYMTPWLSNLVRFCKHNDDAKRQRVTAILDKLITMTINEKQMYPSIQAKIWGSLGQITDLLDVVLDSFIKTSATGGLGSIKAEVMADTAVALASGNVKLVSSKVIGRMCKIIDKTCLSPTPTLEQHLMWDDIAILARYMLMLSFNNSLDVAAHLPYLFHVVTLLVATGPLSLRASTHGLVINIIHSLCTCSQLHFSEETKQVLRLSLTEFSLPKFYLLFGISKVKSAAVIAFRSSYRDRSFSPGSYERETFALTSLETVTEALLEIMEACMRDIPTCKWLDQWTELAQKFAFQYNPSLQPRALVVFGCISKRVSHGQIKQIIRILSKGLESCLKGPDNYNSQVLIEATVIALTKLQPLLNKDSPMHKALFWVAMAVLQLDEVNLYSAGTALLEQNLHTLDSLRVFNDKSPEEVFMEIRRPLEWHCKQMDHFVGLNFNSNFNFALVGHLLKGYRHPSPTTVARTVRILHTLLALVNKHRNCDKFEVNTQSVAYLAALLTVSEEVRSRCSLKHRKSLLLTDVAMENVPMDTYPIHHSDTTYRTLKENQPWSSPKGSDRHLAASYPTVGQISPRTRKSMSLDMGQPSQANTKKLLGTRKSFDHLISDTKAPKRQDMESGITTPPKMRRVAENDYEMETQRISPQQHPHLRKVSVSESNVLLDEEVLTDPKIQALLLTVLATLVKYTTDEFDQRILYEYLAEASVVFPKVFPVVHNLLDSKINTLLSLCQDPNLLNPIHGIVQSVVYHEESPPQYQTSYLQSFGFNGLWRFAGPFSKQTQIPDYAELIVKFLDALIDTYLPGFDEETSEESLLTPTSPYPPAVQSQLSITANLNLSNSMTSLATSQHSPASLPCSKSAVFMQLPHQGIDKENVELSPTTGHTNSGRMRHGSASQVQKQRSAGSLKRHSIKKIV", "length": 2850, "header": "tr|A0A8V1ADH8-1|A0A8V1ADH8_CHICK Isoform 1 of Neurofibromin OS=Gallus gallus OX=9031 GN=NF1 PE=1 SV=1 CANONICAL=A0A8V1ADH8-1" }, "isoforms": [ { "isoform_ac": "A0A8V1ADH8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADH8/entry#A0A8V1ADH8-1", "sequence": { "sequence": "MAAHKPVEWVQAVVNRFDEQLPIKASQQNTHTKVSTEHNKECLINISKYKFSLVISGLTNILKNVNNMRIFGETAEKNLYLSQLIILDTLEKCLAGQPKDTMRLDETMLVKQLLPEICHFIHTYREGNQHAAELRNSASGVLFSLSCNNFNAVFSRISTRLQELTVCSEDNADVHDIELLQYISVDCSKLKRLLQETVFKFKALKKVAQLAVINSLEKAFWNWVENYPDEFTKLYQTPQTDMADCAEKLFDLVDGFAESTKRKAAVWPLQIILLVLCPEIIQDIAKDVVEETKMNKKLFLDNLRKALAGHSGSRQLTESAAIACVKLCKASTYINWEDNSVIFLLVQSMVVDLKNLLFNPSKPFSRSNQNADVDLMIDCLVSCFRINPHNNQHFKICLAQSSPSTFHYVLVNSLHRIITNSALDWWPRIDAVYCHSVELRSMFSETLHKAIQGCGAHPAIRMTPSLTFKEKMTSLKFKEKPTDLETKSYKFLLLSLVKLIHADPKLLLCNPRKQGPETQGSTAELITGLVQLVPQSSMPDIAQEAMEALLVLHQLDSIDLWNPDAPIETFWEISSQMLFYICKKLTSHQMLSSTEILKWLREILICRNKFLLKNKQSDRTSCHFLFLYDVSGGGASQMSLDHEEMMRCAPGATLRKGKGNSSMESTAGCSGTPICRQAQTKLEVALYMFLWSPDIEAVLVAMSCFRHLCEEADIRCGVDEVSVHNFLPNYNTFMEFASVSNMMSTGRAALQKRVMALLRRIEHPTAGNTEAWEDTHAKWEQATKLILNYPKTKMEDGQVTESLHKTIVKRRMSHVSGGGSIDLSDTDSLQEWINMTGFLCALGGVCLQHRSNAGLATYSPPMGPVNERKGSMISMVSTEGNAETPVSKFIDRLLTLMVCNHEKVGLQIRTNIKDLVGLELSPALYPMLFNKLKNTISKFFDSQGQVLLTETNTQFVEQTIAIMKNLLDNHTEGSSEHLGQASIETMMLNLVRYVRVLGNLVHAIQIKTKLCQLVEVMMERRDDLSFCQEMKFRNKMVEYLTDWVMGTSNQATDEDVKCLTRDLDQASMEAVVSLLAGLPLQPEEGDGVELMEAKSQLFLKYFTLFMNLLNDCSEVEDESAQTGGRKRGMSRRLASLRHCTVLAMSNLLNANVDSGLMHSIGLGYHKDLQTRATFMEVLTKILQQGTEFDTLAETVLADRFERLVELVTMMGDQGELPIAMALANVVPCSQWDELARVLVTLFDSRHLLYQLLWNMFSKEVELADSMQTLFRGNSLASKIMTFCFKVYGATYLQKLLEPLLRTVITSSEWQHVSFEVDPTRLEPTESLEENQRSLLQMTEKFFHAIINSSSEFPPQLRSVCHCLYQATCHSLLNKATVKEKKENKKSVVSQRFPQNSIGAVGSAMFLRFINPAIVSPYEAGILDKKPPPRIERGLKLMSKILQSIANHVLFTKEEHMRPFNDFVKSNFDAARRFFLDIASDCPASDTVNHSLSFISDGNVLALHRLLWNNQEKIGQYLSSNRDHKAVGRRPFDKMATLLAYLGPPEHKPVADTHWSSLNLTSSKFEEFMTRHQVHEKEEFKALKTLNIFYQAGTSKAGNPVFYYIARRFKTGQINGDLLIYHVLLTLKPYYAKPYEIVVDLTHAGPSNRFKTDFLSKWFVVFPGFAYENVSAVFIYNCNSWVREYTKYHERLLTGLKGSKRLIFIDSPGKLAEHIEHDQQKLPAATLALEEDLKVFHNALKLAHKDTKVSIKVGSTAVQVTSAERTRVLGQTVFLNDIYYASEIEEICLVDENQFTLTIANQGTPLTFMHQECEAIVRSIIHIRTRWELSQPDSIPQHTKIRPKDVPGTLLNIALLNLGSSDPSLRSAAYNLLCALTCTFNLKIEGQLLETSGLCIPANNTLFIVSISKTLAANEPHLTLEFLEECISGFSKSSIELKHLCLEYMTPWLSNLVRFCKHNDDAKRQRVTAILDKLITMTINEKQMYPSIQAKIWGSLGQITDLLDVVLDSFIKTSATGGLGSIKAEVMADTAVALASGNVKLVSSKVIGRMCKIIDKTCLSPTPTLEQHLMWDDIAILARYMLMLSFNNSLDVAAHLPYLFHVVTLLVATGPLSLRASTHGLVINIIHSLCTCSQLHFSEETKQVLRLSLTEFSLPKFYLLFGISKVKSAAVIAFRSSYRDRSFSPGSYERETFALTSLETVTEALLEIMEACMRDIPTCKWLDQWTELAQKFAFQYNPSLQPRALVVFGCISKRVSHGQIKQIIRILSKGLESCLKGPDNYNSQVLIEATVIALTKLQPLLNKDSPMHKALFWVAMAVLQLDEVNLYSAGTALLEQNLHTLDSLRVFNDKSPEEVFMEIRRPLEWHCKQMDHFVGLNFNSNFNFALVGHLLKGYRHPSPTTVARTVRILHTLLALVNKHRNCDKFEVNTQSVAYLAALLTVSEEVRSRCSLKHRKSLLLTDVAMENVPMDTYPIHHSDTTYRTLKENQPWSSPKGSDRHLAASYPTVGQISPRTRKSMSLDMGQPSQANTKKLLGTRKSFDHLISDTKAPKRQDMESGITTPPKMRRVAENDYEMETQRISPQQHPHLRKVSVSESNVLLDEEVLTDPKIQALLLTVLATLVKYTTDEFDQRILYEYLAEASVVFPKVFPVVHNLLDSKINTLLSLCQDPNLLNPIHGIVQSVVYHEESPPQYQTSYLQSFGFNGLWRFAGPFSKQTQIPDYAELIVKFLDALIDTYLPGFDEETSEESLLTPTSPYPPAVQSQLSITANLNLSNSMTSLATSQHSPASLPCSKSAVFMQLPHQGIDKENVELSPTTGHTNSGRMRHGSASQVQKQRSAGSLKRHSIKKIV", "length": 2850, "header": "tr|A0A8V1ADH8-1|A0A8V1ADH8_CHICK Isoform 1 of Neurofibromin OS=Gallus gallus OX=9031 GN=NF1 PE=1 SV=1 CANONICAL=A0A8V1ADH8-1" }, "locus": { "chromosome": "19", "start_pos": 9568976, "end_pos": 9489727, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071395.1", "url": "https://www.ensembl.org/id/ENSGALT00010071395.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044085.1", "url": "https://www.ensembl.org/id/ENSGALP00010044085.1" } ] } }, { "isoform_ac": "A0A8V1AIW7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADH8/entry#A0A8V1AIW7-1", "sequence": { "sequence": "MCKIIDKTCLSPTPTLEQHLMWDDIAILARYMLMLSFNNSLDVAAHLPYLFHVVTLLVATGPLSLRASTHGLVINIIHSLCTCSQLHFSEETKQVLRLSLTEFSLPKFYLLFGISKVKSAAVIAFRSSYRDRSFSPGSYERETFALTSLETVTEALLEIMEACMRDIPTCKWLDQWTELAQKFAFQYNPSLQPRALVVFGCISKRVSHGQIKQIIRILSKGLESCLKGPDNYNSQVLIEATVIALTKLQPLLNKDSPMHKALFWVAMAVLQLDEVNLYSAGTALLEQNLHTLDSLRVFNDKSPEEVFMEIRRPLEWHCKQMDHFVGLNFNSNFNFALVGHLLKGYRHPSPTTVARTVRILHTLLALVNKHRNCDKFEVNTQSVAYLAALLTVSEEVRSRCSLKHRKSLLLTDVAMENVPMDTYPIHHSDTTYRTLKENQPWSSPKGSDRHLAASYPTVGQISPRTRKSMSLDMGQPSQANTKKLLGTRKSFDHLISDTKAPKRQDMESGITTPPKMRRVAENDYEMETQRISPQQHPHLRKVSVSESNVLLDEEVLTDPKIQALLLTVLATLVKYTTDEFDQRILYEYLAEASVVFPKVFPVVHNLLDSKINTLLSLCQDPNLLNPIHGIVQSVVYHEESPPQYQTSYLQSFGFNGLWRFAGPFSKQTQIPDYAELIVKFLDALIDTYLPGFDEETSEESLLTPTSPYPPAVQSQLSITANLNLSNSMTSLATSQHSPAPWPHRRVLHSPSLCLEALW", "length": 758, "header": "tr|A0A8V1AIW7-1|A0A8V1ADH8_CHICK Computationally mapped isoform of Neurofibromin OS=Gallus gallus OX=9031 GN=NF1 PE=1 SV=1 CANONICAL=A0A8V1ADH8-1" }, "locus": { "chromosome": "19", "start_pos": 9506029, "end_pos": 9492403, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071392.1", "url": "https://www.ensembl.org/id/ENSGALT00010071392.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044082.1", "url": "https://www.ensembl.org/id/ENSGALP00010044082.1" } ] } }, { "isoform_ac": "A0A8V1AKP1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADH8/entry#A0A8V1AKP1-1", "sequence": { "sequence": "MAAHKPVEWVQAVVNRFDEQLPIKASQQNTHTKVSTEHNKECLINISKYKFSLVISGLTNILKNVNNMRIFGETAEKNLYLSQLIILDTLEKCLAGQPKDTMRLDETMLVKQLLPEICHFIHTYREGNQHAAELRNSASGVLFSLSCNNFNAVFSRISTRLQELTVCSEDNADVHDIELLQYISVDCSKLKRLLQETVFKFKALKKVAQLAVINSLEKAFWNWVENYPDEFTKLYQTPQTDMADCAEKLFDLVDGFAESTKRKAAVWPLQIILLVLCPEIIQDIAKDVVEETKMNKKLFLDNLRKALAGHSGSRQLTESAAIACVKLCKASTYINWEDNSVIFLLVQSMVVDLKNLLFNPSKPFSRSNQNADVDLMIDCLVSCFRINPHNNQHFKICLAQSSPSTFHYVLVNSLHRIITNSALDWWPRIDAVYCHSVELRSMFSETLHKAIQGCGAHPAIRMTPSLTFKEKMTSLKFKEKPTDLETKSYKFLLLSLVKLIHADPKLLLCNPRKQGPETQGSTAELITGLVQLVPQSSMPDIAQEAMEALLVLHQLDSIDLWNPDAPIETFWEISSQMLFYICKKLTSHQMLSSTEILKWLREILICRNKFLLKNKQSDRTSCHFLFLYDVSGGGASQMSLDHEEMMRCAPGATLRKGKGNSSMESTAGCSGTPICRQAQTKLEVALYMFLWSPDIEAVLVAMSCFRHLCEEADIRCGVDEVSVHNFLPNYNTFMEFASVSNMMSTGRAALQKRVMALLRRIEHPTAGNTEAWEDTHAKWEQATKLILNYPKTKMEDGQVTESLHKTIVKRRMSHVSGGGSIDLSDTDSLQEWINMTGFLCALGGVCLQHRSNAGLATYSPPMGPVNERKGSMISMVSTEGNAETPVSKFIDRLLTLMVCNHEKVGLQIRTNIKDLVGLELSPALYPMLFNKLKNTISKFFDSQGQVLLTETNTQFVEQTIAIMKNLLDNHTEGSSEHLGQASIETMMLNLVRYVRVLGNLVHAIQIKTKLCQLVEVMMERRDDLSFCQEMKFRNKMVEYLTDWVMGTSNQATDEDVKCLTRDLDQASMEAVVSLLAGLPLQPEEGDGVELMEAKSQLFLKYFTLFMNLLNDCSEVEDESAQTGGRKRGMSRRLASLRHCTVLAMSNLLNANVDSGLMHSIGLGYHKDLQTRATFMEVLTKILQQGTEFDTLAETVLADRFERLVELVTMMGDQGELPIAMALANVVPCSQWDELARVLVTLFDSRHLLYQLLWNMFSKEVELADSMQTLFRGNSLASKIMTFCFKVYGATYLQKLLEPLLRTVITSSEWQHVSFEVDPTRLEPTESLEENQRSLLQMTEKFFHAIINSSSEFPPQLRSVCHCLYQVVSQRFPQNSIGAVGSAMFLRFINPAIVSPYEAGILDKKPPPRIERGLKLMSKILQSIANHVLFTKEEHMRPFNDFVKSNFDAARRFFLDIASDCPASDTVNHSLSFISDGNVLALHRLLWNNQEKIGQYLSSNRDHKAVGRRPFDKMATLLAYLGPPEHKPVADTHWSSLNLTSSKFEEFMTRHQVHEKEEFKALKTLNIFYQAGTSKAGNPVFYYIARRFKTGQINGDLLIYHVLLTLKPYYAKPYEIVVDLTHAGPSNRFKTDFLSKWFVVFPGFAYENVSAVFIYNCNSWVREYTKYHERLLTGLKGSKRLIFIDSPGKLAEHIEHDQQKLPAATLALEEDLKVFHNALKLAHKDTKVSIKVGSTAVQVTSAERTRVLGQTVFLNDIYYASEIEEICLVDENQFTLTIANQGTPLTFMHQECEAIVRSIIHIRTRWELSQPDSIPQHTKIRPKDVPGTLLNIALLNLGSSDPSLRSAAYNLLCALTCTFNLKIEGQLLETSGLCIPANNTLFIVSISKTLAANEPHLTLEFLEECISGFSKSSIELKHLCLEYMTPWLSNLVRFCKHNDDAKRQRVTAILDKLITMTINEKQMYPSIQAKIWGSLGQITDLLDVVLDSFIKTSATGGLGSIKAEVMADTAVALASGNVKLVSSKVIGRMCKIIDKTCLSPTPTLEQHLMWDDIAILARYMLMLSFNNSLDVAAHLPYLFHVVTLLVATGPLSLRASTHGLVINIIHSLCTCSQLHFSEETKQVLRLSLTEFSLPKFYLLFGISKVKSAAVIAFRSSYRDRSFSPGSYERETFALTSLETVTEALLEIMEACMRDIPTCKWLDQWTELAQKFAFQYNPSLQPRALVVFGCISKRVSHGQIKQIIRILSKGLESCLKGPDNYNSQVLIEATVIALTKLQPLLNKDSPMHKALFWVAMAVLQLDEVNLYSAGTALLEQNLHTLDSLRVFNDKSPEEVFMEIRRPLEWHCKQMDHFVGLNFNSNFNFALVGHLLKGYRHPSPTTVARTVRILHTLLALVNKHRNCDKFEVNTQSVAYLAALLTVSEEVRSRCSLKHRKSLLLTDVAMENVPMDTYPIHHSDTTYRTLKENQPWSSPKGSDRHLAASYPTVGQISPRTRKSMSLDMGQPSQANTKKLLGTRKSFDHLISDTKAPKRQDMESGITTPPKMRRVAENDYEMETQRISPQQHPHLRKVSVSESNVLLDEEVLTDPKIQALLLTVLATLVKYTTDEFDQRILYEYLAEASVVFPKVFPVVHNLLDSKINTLLSLCQDPNLLNPIHGIVQSVVYHEESPPQYQTSYLQSFGFNGLWRFAGPFSKQTQIPDYAELIVKFLDALIDTYLPGFDEETSEESLLTPTSPYPPAVQSQLSITANLNLSNSMTSLATSQHSPASLPCSKSAVFMQLPHQGIDKENVELSPTTGHTNSGRMRHGSASQVQKQRSAGSLKRHSIKKIV", "length": 2829, "header": "tr|A0A8V1AKP1-1|A0A8V1ADH8_CHICK Computationally mapped isoform of Neurofibromin OS=Gallus gallus OX=9031 GN=NF1 PE=1 SV=1 CANONICAL=A0A8V1ADH8-1" }, "locus": { "chromosome": "19", "start_pos": 9568976, "end_pos": 9489727, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071394.1", "url": "https://www.ensembl.org/id/ENSGALT00010071394.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044084.1", "url": "https://www.ensembl.org/id/ENSGALP00010044084.1" } ] } }, { "isoform_ac": "A0A8V1AMK4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADH8/entry#A0A8V1AMK4-1", "sequence": { "sequence": 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"length": 2827, "header": "tr|A0A8V1AMK4-1|A0A8V1ADH8_CHICK Computationally mapped isoform of Neurofibromin OS=Gallus gallus OX=9031 GN=NF1 PE=1 SV=1 CANONICAL=A0A8V1ADH8-1" }, "locus": { "chromosome": "19", "start_pos": 9568976, "end_pos": 9489727, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071393.1", "url": "https://www.ensembl.org/id/ENSGALT00010071393.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044083.1", "url": "https://www.ensembl.org/id/ENSGALP00010044083.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2061, "start_aa": "Thr", "end_pos": 2061, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2061", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2505, "start_aa": "Thr", "end_pos": 2505, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2505", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-GGA-5658442", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5658442", "resource": "Reactome", "description": "Regulation of RAS by GAPs" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADH8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADH8" } ], "pmid": "" }, { "name": "phosphatidylethanolamine binding", "id": "GO:0008429", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008429", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADH8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADH8" } ], "pmid": "" }, { "name": "phosphatidylcholine binding", "id": "GO:0031210", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031210", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADH8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADH8" } ], "pmid": "" }, { "name": "lipid binding", "id": "GO:0008289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008289", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADH8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADH8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADH8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADH8" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADH8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADH8" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADH8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADH8" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADH8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADH8" } ], "pmid": "" }, { "name": "axon", "id": "GO:0030424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030424", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADH8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADH8" } ], "pmid": "" }, { "name": "dendrite", "id": "GO:0030425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADH8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADH8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "regulation of blood vessel endothelial cell migration", "id": "GO:0043535", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043535", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADH8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADH8" } ], "pmid": "" }, { "name": "cognition", "id": "GO:0050890", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050890", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADH8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADH8" } ], "pmid": "" }, { "name": "regulation of intracellular signal transduction", "id": "GO:1902531", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902531", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADH8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADH8" } ], "pmid": "" }, { "name": "regulation of angiogenesis", "id": "GO:0045765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045765", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADH8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADH8" } ], "pmid": "" }, { "name": "regulation of developmental process", "id": "GO:0050793", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050793", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADH8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADH8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1347, "end_pos": 1349, "annotation": 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{ "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1ADI2-1", "uniprot_ac": "A0A8V1ADI2", "uniprot_id": "A0A8V1ADI2_CHICK", "mass": { "chemical_mass": 8668.0, "monoisotopic_mass": 8668.0 }, "refseq": { "ac": "NP_001384566", "name": "epidermal differentiation protein containing cysteine histidine motifs 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384566" }, "gene_names": [ { "name": "MHM2", "type": "recommended", "evidence": [ { "id": "A0A8V1ADI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADI2" } ] }, { "name": "EDCH1", "type": "synonym", "evidence": [ { "id": "NP_001384566", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384566" } ] }, { "name": "MHM2", "type": "synonym", "evidence": [ { "id": "NP_001384566", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384566" } ] } ], "protein_names": [ { "name": "Male hypermethylated region 2", "type": "synonym", "evidence": [ { "id": "A0A8V1ADI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADI2/entry#names_and_taxonomy" } ] }, { "name": "epidermal differentiation protein containing cysteine histidine motifs 1", "type": "synonym", "evidence": [ { "id": "NP_001384566", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384566" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: HAEK01148848.1, SRR12888542.239859.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN02738218, SAMN02738220 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from HAEK01148848.1 and JAENSK010000349.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001384566", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384566" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADI2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADI2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MHM2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADI2", "locus": { "chromosome": "25", "start_pos": 1703584, "end_pos": 1704371, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028364", "url": "https://www.ensembl.org/id/ENSGALG00010028364" } ] } } ], "crossref": [ { "id": "A0A8V1ADI2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1ADI2", "database": "AlphaFoldDB", "categories": [] }, { "id": "110224118", "url": "https://www.ncbi.nlm.nih.gov/gene/110224118", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "GANKSCH", "url": "https://omabrowser.org/oma/group/GANKSCH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ADI2", "url": "https://www.orthodb.org/?gene=A0A8V1ADI2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "NP_001384566", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384566", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1ADI2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADI2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ADI2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADI2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGSSESCHSQNPSCHSSHACNDSGPSCHSSSQNVPAPMYACVTPCSPPAQTYCVPTQCYPPPVQTCPQNTNAACNLPPPCPKF", "length": 83, "header": "tr|A0A8V1ADI2-1|A0A8V1ADI2_CHICK Isoform 1 of Male hypermethylated region 2 OS=Gallus gallus OX=9031 GN=MHM2 PE=4 SV=1 CANONICAL=A0A8V1ADI2-1" }, "isoforms": [ { "isoform_ac": "A0A8V1ADI2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADI2/entry#A0A8V1ADI2-1", "sequence": { "sequence": "MGSSESCHSQNPSCHSSHACNDSGPSCHSSSQNVPAPMYACVTPCSPPAQTYCVPTQCYPPPVQTCPQNTNAACNLPPPCPKF", "length": 83, "header": "tr|A0A8V1ADI2-1|A0A8V1ADI2_CHICK Isoform 1 of Male hypermethylated region 2 OS=Gallus gallus OX=9031 GN=MHM2 PE=4 SV=1 CANONICAL=A0A8V1ADI2-1" }, "locus": { "chromosome": "25", "start_pos": 1703896, "end_pos": 1703648, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068714.1", "url": "https://www.ensembl.org/id/ENSGALT00010068714.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042224.1", "url": "https://www.ensembl.org/id/ENSGALP00010042224.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 43, "start_aa": "Thr", "end_pos": 43, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr43", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 21, "end_pos": 23, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 43 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 21, "end_pos": 23 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1ADJ4-1", "uniprot_ac": "A0A8V1ADJ4", "uniprot_id": "A0A8V1ADJ4_CHICK", "mass": { "chemical_mass": 44578.0, "monoisotopic_mass": 44578.0 }, "refseq": { "ac": "XP_046760618", "name": "C2 calcium-dependent domain-containing protein 4C", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046760618" }, "gene_names": [ { "name": "C2CD4C", "type": "recommended", "evidence": [ { "id": "A0A8V1ADJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADJ4" } ] }, { "name": "C2CD4C", "type": "synonym", "evidence": [ { "id": "XP_046760618", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046760618" } ] } ], "protein_names": [ { "name": "C2 calcium dependent domain containing 4C", "type": "synonym", "evidence": [ { "id": "A0A8V1ADJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADJ4/entry#names_and_taxonomy" } ] }, { "name": "C2 calcium-dependent domain-containing protein 4C", "type": "synonym", "evidence": [ { "id": "XP_046760618", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046760618" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052559.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_046760618", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046760618" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADJ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADJ4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "C2CD4C", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADJ4", "locus": { "chromosome": "28", "start_pos": 3063404, "end_pos": 3069100, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027249", "url": "https://www.ensembl.org/id/ENSGALG00010027249" } ] } } ], "crossref": [ { "id": "428334", "url": "https://www.ncbi.nlm.nih.gov/gene/428334", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000008", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000008", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035892", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035892", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043549", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043549", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "DKHCDAR", "url": "https://omabrowser.org/oma/group/DKHCDAR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ADJ4", "url": "https://www.orthodb.org/?gene=A0A8V1ADJ4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46291", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46291", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46291:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46291:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00168", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00168", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_046760618", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046760618", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1ADJ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADJ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ADJ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADJ4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MWLLERLRGMAENSGARGSGPDDSPRGSRYSNVLTPDKIPDFFIPPKLSAAPAEPEGTEPTAPPILGPSVSEQDLTDRKTPRSPRPPSRPRAKASGRHIIQIESAEDWTAEGGFGTNVDPQAQTAMSLPYVPKAQTSYGFATLVESPHTRRKESLFHSEHSSLCPSPATSPSAQRRAKLNGESRAQAPSDLGAALMHPGRYFSGGESDTCSSAESSPFGSPLLSRSVSLLKIFSQESQSKVIKLKHSVARNSSLSTDDSSADTSPSAQRRSRSAPAGGQPAAGTELPQGRPREHSLRLSRGGRLRLTADYDPSNARLRVQLICAEDLYDALVDVRGIHCCVSLCLNPGKLQKQRSTIIKNSRNPVFNEDFFFDGLGPSHVRKLSLKLKVVNKGSSLKRDTLLGEKELPLSALL", "length": 413, "header": "tr|A0A8V1ADJ4-1|A0A8V1ADJ4_CHICK Isoform 1 of C2 calcium dependent domain containing 4C OS=Gallus gallus OX=9031 GN=C2CD4C PE=4 SV=1 CANONICAL=A0A8V1ADJ4-1" }, "isoforms": [ { "isoform_ac": "A0A8V1ADJ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADJ4/entry#A0A8V1ADJ4-1", "sequence": { "sequence": "MWLLERLRGMAENSGARGSGPDDSPRGSRYSNVLTPDKIPDFFIPPKLSAAPAEPEGTEPTAPPILGPSVSEQDLTDRKTPRSPRPPSRPRAKASGRHIIQIESAEDWTAEGGFGTNVDPQAQTAMSLPYVPKAQTSYGFATLVESPHTRRKESLFHSEHSSLCPSPATSPSAQRRAKLNGESRAQAPSDLGAALMHPGRYFSGGESDTCSSAESSPFGSPLLSRSVSLLKIFSQESQSKVIKLKHSVARNSSLSTDDSSADTSPSAQRRSRSAPAGGQPAAGTELPQGRPREHSLRLSRGGRLRLTADYDPSNARLRVQLICAEDLYDALVDVRGIHCCVSLCLNPGKLQKQRSTIIKNSRNPVFNEDFFFDGLGPSHVRKLSLKLKVVNKGSSLKRDTLLGEKELPLSALL", "length": 413, "header": "tr|A0A8V1ADJ4-1|A0A8V1ADJ4_CHICK Isoform 1 of C2 calcium dependent domain containing 4C OS=Gallus gallus OX=9031 GN=C2CD4C PE=4 SV=1 CANONICAL=A0A8V1ADJ4-1" }, "locus": { "chromosome": "28", "start_pos": 3066911, "end_pos": 3065673, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066070.1", "url": "https://www.ensembl.org/id/ENSGALT00010066070.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040336.1", "url": "https://www.ensembl.org/id/ENSGALP00010040336.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A287BPK3-1", "protein_name": "C2 calcium-dependent domain-containing protein 4C", "gene_name": "C2CD4C", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MKKTNMWFLERLRGSGENGATGGEGGDKAAKGPLYSNVLTPDKIPDFFIPPKLPASPAEPEGQAELGPSTSEQNLASAPPRRGPRSPRLPAKLAAESKSLLKAATRHVIQIESAEDWPAEEAATNADPQAQGAMSLPSVPKAQTSYGFTTLAESPHTRRKESLFHSEHGALAQVGSPGTRRRRGTAKGNGGDGAPREASGALMSPGRCVSGGESDTASSAESSPFGSPLLSRSVSLLKGFAQDSQAKVSQLKHSVGRHGSLSADDSTPDTSPGTRRRFPRRAAPEPGPEPSPTPRAEHAVRMGVRGSVRLLAEYEAAQARLRVRLLAAEGLYDRLCDARSINCCVGLCLVPGKLQKQRSTIVKNSRHPVFNEDFFFDGLGPASVPKLALRIKVVNKGSSLKRDTLLGEKELPLTSLLPFL", "length": 420 }, "evidence": [ { "id": "A0A8V1ADJ4", "url": "https://omabrowser.org/oma/group/A0A8V1ADJ4/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3N2V3-1", "protein_name": "C2 calcium-dependent 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"publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1ADJ7-1", "uniprot_ac": "A0A8V1ADJ7", "uniprot_id": "A0A8V1ADJ7_CHICK", "mass": { "chemical_mass": 34818.0, "monoisotopic_mass": 34818.0 }, "refseq": {}, "gene_names": [ { "name": "HAX1", "type": "recommended", "evidence": [ { "id": "A0A8V1ADJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADJ7" } ] } ], "protein_names": [ { "name": "HCLS1 associated protein X-1", "type": "synonym", "evidence": [ { "id": "A0A8V1ADJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADJ7/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADJ7" } ], "common_name": 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[ { "database": "UniProtKB", "id": "A0A8V1ADJ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADJ9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RUSC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADJ9", "locus": { "chromosome": "25", "start_pos": 2125766, "end_pos": 2119194, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028380", "url": "https://www.ensembl.org/id/ENSGALG00010028380" } ] } } ], "crossref": [ { "id": "A0A8V1ADJ9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1ADJ9", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd17701", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17701", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004012", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004012", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036028", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036028", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037213", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037213", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047341", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047341", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047343", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047343", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ADJ9", "url": "https://www.orthodb.org/?gene=A0A8V1ADJ9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AK92", "url": "https://www.orthodb.org/?gene=A0A8V1AK92", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15591", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15591", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15591:SF11", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15591:SF11", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00018", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00018", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02759", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02759", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1ADJ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADJ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ADJ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADJ9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AK92", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK92", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AK92-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK92-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLAPKKGLLCNLNHIHLQHISLGLHLSRHPELQDTAGSGDQKRCSSCRESCEQVDANSNSPSLKCHCCESHAELPLTLGLQNQAAPAVDLPRLQDGEEVVSPSDPPSTSSSVSSCSDFSLDESPVSVYYRGFSAEGSQSPTEPPGAVPAEDAHDGRLLPATGGERDADLNPAAPQGEQNLTGDSPDSLCSSSSLDSQYDETSPGAAVRQNADGSVDLDPRGSGEAEHGEEAHQEARPSPPAAGAPGAAQPHGDGPEGRRGALAEQKKALLIAVSTAVDKVIAHFSSARNVVQKAQLGDSWLSPDVGYLLLHTLCPALYGLVEDGLKPFQKDVITGQRRNSPWSVVEASVKTGPNTRSLHNLCWRVAGLAPLSSTRQKFHAFILGLLNTKQLEQWVSHLHNSPGVVSMLYFPTAFFALSQGPLPHLADELLLLIQPLSVLTFHLDLLFEHHHLSVDVRPLSRRMESPPSPTPRFAQGAAQPLEGQSGTAGVSLEDELPPDTLGRAPAAEESPRSPCQAAVRSPLPGPQVGAALQQTFQHVLRWGDQLSRAFLGADSSPGAVRPEAGPWDTGAGPSSWWAQLSQASRIYTAPSKERFPFIWWTKLRTAAGDSSPGQVAQTPLREPKGTELQLLQTKAIPELSSPNSSGSADTSGTSSPEDLVLLTGTPLPPAGPAAGEKPPAASPQPGAGRSQAAPPDPGPCSPGPDRGSWLGRLFGASSPSARSSPPSPDAISVRSRRPSRWLSPSSHVLAVVVKGLAAEKSRAPEQPERKLPDLPQTHRAVRALCDHTGAADGHLSFQKGDVLQLLSTVDEDWIRCCHGNRTGLVPVGYTSLIL", "length": 834, "header": "tr|A0A8V1ADJ9-1|A0A8V1ADJ9_CHICK Isoform 1 of RUN and SH3 domain containing 1 OS=Gallus gallus OX=9031 GN=RUSC1 PE=1 SV=1 CANONICAL=A0A8V1ADJ9-1" }, "isoforms": [ { "isoform_ac": "A0A8V1ADJ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADJ9/entry#A0A8V1ADJ9-1", "sequence": { "sequence": "MLAPKKGLLCNLNHIHLQHISLGLHLSRHPELQDTAGSGDQKRCSSCRESCEQVDANSNSPSLKCHCCESHAELPLTLGLQNQAAPAVDLPRLQDGEEVVSPSDPPSTSSSVSSCSDFSLDESPVSVYYRGFSAEGSQSPTEPPGAVPAEDAHDGRLLPATGGERDADLNPAAPQGEQNLTGDSPDSLCSSSSLDSQYDETSPGAAVRQNADGSVDLDPRGSGEAEHGEEAHQEARPSPPAAGAPGAAQPHGDGPEGRRGALAEQKKALLIAVSTAVDKVIAHFSSARNVVQKAQLGDSWLSPDVGYLLLHTLCPALYGLVEDGLKPFQKDVITGQRRNSPWSVVEASVKTGPNTRSLHNLCWRVAGLAPLSSTRQKFHAFILGLLNTKQLEQWVSHLHNSPGVVSMLYFPTAFFALSQGPLPHLADELLLLIQPLSVLTFHLDLLFEHHHLSVDVRPLSRRMESPPSPTPRFAQGAAQPLEGQSGTAGVSLEDELPPDTLGRAPAAEESPRSPCQAAVRSPLPGPQVGAALQQTFQHVLRWGDQLSRAFLGADSSPGAVRPEAGPWDTGAGPSSWWAQLSQASRIYTAPSKERFPFIWWTKLRTAAGDSSPGQVAQTPLREPKGTELQLLQTKAIPELSSPNSSGSADTSGTSSPEDLVLLTGTPLPPAGPAAGEKPPAASPQPGAGRSQAAPPDPGPCSPGPDRGSWLGRLFGASSPSARSSPPSPDAISVRSRRPSRWLSPSSHVLAVVVKGLAAEKSRAPEQPERKLPDLPQTHRAVRALCDHTGAADGHLSFQKGDVLQLLSTVDEDWIRCCHGNRTGLVPVGYTSLIL", "length": 834, "header": "tr|A0A8V1ADJ9-1|A0A8V1ADJ9_CHICK Isoform 1 of RUN and SH3 domain containing 1 OS=Gallus gallus OX=9031 GN=RUSC1 PE=1 SV=1 CANONICAL=A0A8V1ADJ9-1" }, "locus": { "chromosome": "25", "start_pos": 2125311, "end_pos": 2119814, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068765.1", "url": "https://www.ensembl.org/id/ENSGALT00010068765.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042240.1", "url": "https://www.ensembl.org/id/ENSGALP00010042240.1" } ] } }, { "isoform_ac": "A0A8V1AK92-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADJ9/entry#A0A8V1AK92-1", "sequence": { "sequence": "MQSCPCRAAPGSAPAVRGGPGGAGGPVGTPGGRERLSTERRRIRRPGPPHPPPELRAQRSPTGTARRDGAVLWRSRRKAQLGDSWLSPDVGYLLLHTLCPALYGLVEDGLKPFQKDVITGQRRNSPWSVVEASVKTGPNTRSLHNLCWRVAGLAPLSSTRQKFHAFILGLLNTKQLEQWVSHLHNSPGVVSMLYFPTAFFALSQGPLPHLADELLLLIQPLSVLTFHLDLLFEHHHLSVDVRPLSRRMESPPSPTPRFAQGAAQPLEGQSGTAGVSLEDELPPDTLGRAPAAEESPRSPCQAAVRSPLPGPQVGAALQQTFQHVLRWGDQLSRAFLGADSSPGAVRPEAGPWDTGAGPSSWWAQLSQASRIYTAPSKERFPFIWWTKLRTAAGDSSPGQVAQTPLREPKGTELQLLQTKAIPELSSPNSSGSADTSGTSSPEDLVLLTGTPLPPAGPAAGEKPPAASPQPGAGRSQAAPPDPGPCSPGPDRGSWLGRLFGASSPSARSSPPSPDAISVRSRRPSRWLSPSSHVLAVVVKGLAAEKSRAPEQPERKLPDLPQTHRAVRALCDHTGAADGHLSFQKGDVLQLLSTVDEDWIRCCHGNRTGLVPVGYTSLIL", "length": 619, "header": "tr|A0A8V1AK92-1|A0A8V1ADJ9_CHICK Computationally mapped isoform of RUN and SH3 domain containing 1 OS=Gallus gallus OX=9031 GN=RUSC1 PE=1 SV=1 CANONICAL=A0A8V1ADJ9-1" }, "locus": { "chromosome": "25", "start_pos": 2125311, "end_pos": 2121157, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068761.1", "url": "https://www.ensembl.org/id/ENSGALT00010068761.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042239.1", "url": "https://www.ensembl.org/id/ENSGALP00010042239.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 470, "start_aa": "Thr", "end_pos": 470, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr470", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADJ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADJ9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "early endosome", "id": "GO:0005769", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005769", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADJ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADJ9" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADJ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADJ9" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADJ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADJ9" } ], "pmid": "" }, { "name": "microtubule cytoskeleton", "id": "GO:0015630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015630", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADJ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADJ9" } ], "pmid": "" }, { "name": "cytoplasmic vesicle", "id": "GO:0031410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031410", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADJ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADJ9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "protein polyubiquitination", "id": "GO:0000209", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000209", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADJ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADJ9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 179, "end_pos": 181, "annotation": "n_glycosylation_sequon" }, { "start_pos": 643, "end_pos": 645, "annotation": "n_glycosylation_sequon" }, { "start_pos": 820, "end_pos": 822, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1ADJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADJ9" }, { "id": "PS50826", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50826" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RUN", "eco_id": "ECO_0000259", "start_pos": 304, "end_pos": 448, "start_aa": "Asp", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1ADJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADJ9" }, { "id": "PS50002", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50002" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SH3", "eco_id": "ECO_0000259", "start_pos": 776, "end_pos": 834, "start_aa": "Gln", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 470 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 179, "end_pos": 181 }, { "start_pos": 643, "end_pos": 645 }, { "start_pos": 820, "end_pos": 822 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1ADK2-1", "uniprot_ac": "A0A8V1ADK2", "uniprot_id": "A0A8V1ADK2_CHICK", "mass": { "chemical_mass": 55570.0, "monoisotopic_mass": 55570.0 }, "refseq": { "ac": "XP_004948488", "name": "fibroblast growth factor receptor substrate 3 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004948488" }, "gene_names": [ { "name": "FRS3", "type": "recommended", "evidence": [ { "id": "A0A8V1ADK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADK2" } ] }, { "name": "FRS3", "type": "synonym", "evidence": [ { "id": "XP_004948488", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004948488" } ] } ], "protein_names": [ { "name": "Fibroblast growth factor receptor substrate 3", "type": "synonym", "evidence": [ { "id": "A0A8V1ADK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADK2/entry#names_and_taxonomy" } ] }, { "name": "fibroblast growth factor receptor substrate 3 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_004948488", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004948488" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052557.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004948488.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004948488", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004948488" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADK2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADK2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FRS3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADK2", "locus": { "chromosome": "26", "start_pos": 4997084, "end_pos": 5004264, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027874", "url": "https://www.ensembl.org/id/ENSGALG00010027874" } ] } } ], "crossref": [ { "id": "A0A8V1ADK2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1ADK2", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd01202", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01202", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "419923", "url": "https://www.ncbi.nlm.nih.gov/gene/419923", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002404", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002404", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038742", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038742", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050996", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050996", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:419923", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419923", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CPEQPRQ", "url": "https://omabrowser.org/oma/group/CPEQPRQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ADK2", "url": "https://www.orthodb.org/?gene=A0A8V1ADK2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21258", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21258", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21258:SF39", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21258:SF39", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02174", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02174", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-5654693", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5654693", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5654700", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5654700", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5654706", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5654706", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5654712", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5654712", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5673001", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5673001", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9696270", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9696270", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_004948488", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004948488", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1ADK2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADK2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ADK2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADK2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGSCCSCLCRDSIPDNHPTKFKVTNVDDEGNELGSGVMELTQTELILHTHKRDAVRWPYLCLRRYGYDSNLFSFESGRRCHTGQGIFAFKCSRAEEIFNLLQDLMQCNSINTVEEPVVITRDSHPTEREHSQTPQAPTSLGYTIPGFANGFHSFPGESLSYLAARHPSISSLRHSSVGEDSTHALIGPDDQSHTYVNTANGDQELRGQHCMHSLPEVHPPFPHRKRSCSLEDRNPQVFLQPGEVKFVLGPAPNYRRISRHHRECRTHFCAPNNNNEREDECPSPQCVYENVNGLLPPSTSSLCRGGRVKVPHEEKGSSSCSHRRAALLHYENLPSLPPVWECQLLRRGEEHTGDALTPSPNGYPEAGEEDPLQNYMNSESTALHGGSSLRRGTFLPKPQRGCVPSVFSFDFPRPRLEQPRQLNYIQVELEAEPHKGHPNVSASRARPAASHEAHRTDSYAVIDLKKTAAMSNLQRARPRDDGTSRKTRHNSTDLPL", "length": 496, "header": "tr|A0A8V1ADK2-1|A0A8V1ADK2_CHICK Isoform 1 of Fibroblast growth factor receptor substrate 3 OS=Gallus gallus OX=9031 GN=FRS3 PE=4 SV=1 CANONICAL=A0A8V1ADK2-1" }, "isoforms": [ { "isoform_ac": "A0A8V1ADK2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADK2/entry#A0A8V1ADK2-1", "sequence": { "sequence": "MGSCCSCLCRDSIPDNHPTKFKVTNVDDEGNELGSGVMELTQTELILHTHKRDAVRWPYLCLRRYGYDSNLFSFESGRRCHTGQGIFAFKCSRAEEIFNLLQDLMQCNSINTVEEPVVITRDSHPTEREHSQTPQAPTSLGYTIPGFANGFHSFPGESLSYLAARHPSISSLRHSSVGEDSTHALIGPDDQSHTYVNTANGDQELRGQHCMHSLPEVHPPFPHRKRSCSLEDRNPQVFLQPGEVKFVLGPAPNYRRISRHHRECRTHFCAPNNNNEREDECPSPQCVYENVNGLLPPSTSSLCRGGRVKVPHEEKGSSSCSHRRAALLHYENLPSLPPVWECQLLRRGEEHTGDALTPSPNGYPEAGEEDPLQNYMNSESTALHGGSSLRRGTFLPKPQRGCVPSVFSFDFPRPRLEQPRQLNYIQVELEAEPHKGHPNVSASRARPAASHEAHRTDSYAVIDLKKTAAMSNLQRARPRDDGTSRKTRHNSTDLPL", "length": 496, "header": "tr|A0A8V1ADK2-1|A0A8V1ADK2_CHICK Isoform 1 of Fibroblast growth factor receptor substrate 3 OS=Gallus gallus OX=9031 GN=FRS3 PE=4 SV=1 CANONICAL=A0A8V1ADK2-1" }, "locus": { "chromosome": "26", "start_pos": 5004241, "end_pos": 4998088, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067553.1", "url": "https://www.ensembl.org/id/ENSGALT00010067553.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041296.1", "url": "https://www.ensembl.org/id/ENSGALP00010041296.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:419923", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419923", "resource": "KEGG Pathway" }, { "id": "R-GGA-5654693", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5654693", "resource": "Reactome", "description": "FRS-mediated FGFR1 signaling" }, { "id": "R-GGA-5654700", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5654700", "resource": "Reactome", "description": "FRS-mediated FGFR2 signaling" }, { "id": "R-GGA-5654706", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5654706", "resource": "Reactome", "description": "FRS-mediated FGFR3 signaling" }, { "id": "R-GGA-5654712", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5654712", "resource": "Reactome", "description": "FRS-mediated FGFR4 signaling" }, { "id": "R-GGA-5673001", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5673001", "resource": "Reactome", "description": "RAF/MAP kinase cascade" }, { "id": "R-GGA-9696270", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9696270", "resource": "Reactome", "description": "RND2 GTPase cycle" } ], "orthologs": [ { "uniprot_canonical_ac": "E7F020-1", "protein_name": "Fibroblast growth factor receptor substrate 2", "gene_name": "frs3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGSCWSCLYRDAIQDNHLNKFKVTNVDDEGNELGSGTMELTQTELILHTRKRDAIRWPYLCLRRYGYDSNLFSFESGRRCQTGQGIFAFKCSRAEEIFNLLQELMQCNSINVVEEPMIMTRPGHAPEMDMPRTPQTPNTPAFPMQGFPNGYPGYPISADSSQPSLTNDHRHSLMGLDDQTHTYVNTVGMETDLSSRHCVHSLPEVRPATYPEATTTTTTIRGGPIPGQPGMHCCPLDDPHKDPQVFLQPGAQEVKFMLGPTPAQRHLMERDRERHVPHSLRAPDGSSETEGEETPPVHMCNTHSYHHCHHLMHRHPSMEPCPESQLTYENINGLRGARRQRLSPSTVSQSQSLGSSSSSSTTGDSRTHTHPHSLPLTHTHTSSLPPQGYGCDRGMVAAGHRRTALLNYENLPSLPPVWEYRALQREEEEDQDEDEDEDEYEEEEEEEYDEYEYSEGPATPNGYHQESGGGGIHRDALQNYVNTEQLPPPTRLRHACPPHPHPPERANRVFNFDFRRQRAGRGSSICEQHSRHPPPPPSRQLNYIQVDLEGEPSGCSGHSGGAPVPQRPPPLKRGMAAAAAPPSSRRGECYAVIDLKKTAAMSNLQKALPRDDGTSRKTRHNSTDLPL", "length": 627 }, "evidence": [ { "id": "A0A8V1ADK2", "url": "https://omabrowser.org/oma/group/A0A8V1ADK2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1RUW8-1", "protein_name": "Fibroblast growth factor receptor substrate 3", "gene_name": "FRS3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGSCCSCLNRDSVPDNHPTKFKVTNVDDEGVELGSGVMELTQSELVLHLHRREAVRWPYLCLRRYGYDSNLFSFESGRRCQTGQGIFAFKCSRAEEIFNLLQDLMQCNSINVMEEPVIITRNSHPAELDLPRAPQPPSALGYTVSSFSNGFPGCPGEGPRFSAPRRPSTSSLRHPSLGEESTHALIAPDEQSHTYVNTPTGEDEHRRSRHCLQPLPEGQAPLAPQARASDQRAPQVFLQPGQVKFVLGPTPARRQVTKCQGLCPGLQDAPPNNNNNEGPSECPAQPRCTYENISAGLRPGAGWRLSPEEPGWNGLAHRRAALLHYENLPSLPPVWESQAQPLGEEAAEDGDSRDGLTPSSNGFPEGEEDETPLQKPTSTRAALRSHGSFPVPLTRRRGSPRVFNFDFRRPGPEPPRQLNYIQVELKGWGGDRPKGPQNPSAPRAPVPITHPARSSDSYAVIDLKKTVAMSNLQRALPRDDGTARKTRHNSTDLPL", "length": 495 }, "evidence": [ { "id": "A0A8V1ADK2", "url": "https://omabrowser.org/oma/group/A0A8V1ADK2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3I108-1", "protein_name": "Fibroblast growth factor receptor substrate 3", "gene_name": "Frs3", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MGSCCSCLDRDSVPHNHPTKFKVTNVDDEGVELGSGVMELTQSELVLHLHQREAVRWPYLCLRRYGYDSNLFSFESGRRCQTGQGIFAFKCSRAEEIFNLLQDLMQCNSINVMEEPVIITRNSHPPELDLPRGPSQPTGYTISSLSNGYPGCPGEGPRFSAPRRPSTSSLLHPSLGEESTHTLIGSDEQSHTYVNTPRGEEDHRRSRYCLQPLPEGRAPFPPQTRVSDQRDAQVFLQPGQVKFVLGPTPARRQVKCQTLCPSMHDPSHHNNNEGPSECPAQPKCTYENVSQGNLRQGSGWRLSPEEPGWSGLAHRRAALLHYENLPPLPPVWESQVQQLGGEAGDDGDSRDGLTPSSNGFPDGEEDETPLQKPTSTRASARSHSSFPVPLTRRRGSPRVFNFDFRRPGPEPSRQLNYIQVELKGWGTDRPKGSQNPSVSGAPGPTPHPVRSSDSYAVIDLKKTVAMSNLQRALPRDDGTVRKTRHNSTDLPL", "length": 492 }, "evidence": [ { "id": "A0A8V1ADK2", "url": "https://omabrowser.org/oma/group/A0A8V1ADK2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q91WJ0-1", "protein_name": "Fibroblast growth factor receptor substrate 3", "gene_name": "Frs3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGSCWSCLDRDSVPHNHPTKFKVTNVDDEGVELGSGVMELTQSELVLHLHQREAVRWPYLCLRRYGYDSNLFSFESGRRCQTGQGIFAFKCSRAEDIFNLLQDLMQCNSINVTEEPVIITRSSHPPELDLPRGPPQPAGYTVSGFSNGFPGCPGEGPRFSSAPRRPSTSSLRHPSPGEESTHTLIASEEQSHTYVNTPTGDEDGRSRHCLQPLPEGRVPLPAQTQGSDQRDPQVLLQPGQVKFVLGPTPARRQVMKCQSLCPGMQDPPHHNNNEGPSECPAQPKCTYENVSGGLQQGAGWRLSPEERGWSGLAHRRAALLHYENLPPLPPVWESQGQQPGGEAGDDGDSRDGLTPSSNGFPDGEEDETPLQKPTSTRASARSHSGFPVPLTRRRGSPRVFNFDFRRQGPEPPRQLNYIQVELKGWGTARPKGPQNPSVSGAPGPTPHPVRSSDSYAVIDLKKTAAMSDLQRALPRDDGAVRKTRHNSTDLPL", "length": 492 }, "evidence": [ { "id": "A0A8V1ADK2", "url": "https://omabrowser.org/oma/group/A0A8V1ADK2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADK2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADK2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADK2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADK2" } ], "pmid": "" }, { "name": "transmembrane receptor protein tyrosine kinase adaptor activity", "id": "GO:0005068", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005068", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADK2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADK2" } ], "pmid": "" }, { "name": "fibroblast growth factor receptor binding", "id": "GO:0005104", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005104", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADK2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADK2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "fibroblast growth factor receptor signaling pathway", "id": "GO:0008543", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008543", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADK2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADK2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 439, "end_pos": 441, "annotation": "n_glycosylation_sequon" }, { "start_pos": 490, "end_pos": 492, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1ADK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADK2" }, { "id": "PS51064", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51064" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "IRS-type PTB", "eco_id": "ECO_0000259", "start_pos": 13, "end_pos": 115, "start_aa": "Ile", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 439, "end_pos": 441 }, { "start_pos": 490, "end_pos": 492 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1ADL2-1", "uniprot_ac": "A0A8V1ADL2", "uniprot_id": "A0A8V1ADL2_CHICK", "mass": { "chemical_mass": 63856.0, "monoisotopic_mass": 63856.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Zinc finger protein 777", "type": "recommended", "evidence": [ { "id": "A0A8V1ADL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADL2/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "May be involved in transcriptional regulation.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADL2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADL2#function" }, { "database": "UniProtKB", "id": "ARBA00003767", "url": "https://www.uniprot.org/uniprotkb/ARBA00003767#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADL2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADL2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADL2", "locus": {} } ], "crossref": [ { "id": "A0A8V1ADL2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1ADL2", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd07765", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07765", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001909", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001909", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036051", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036051", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050752", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050752", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR24384", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24384", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24384:SF243", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24384:SF243", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01352", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01352", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-212436", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-212436", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1ADL2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADL2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ADL2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADL2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAEWAPAQDLEWAMEPQELSLEQPLAAPEEGPGREAELPAAEISVTLVTEVQAVDRKVEAQAAQLMNLEGRMRMAESKLIGCERTAVEFGNQLESKWTALGTLIQEYGQLQKRLENMENLLKNRNFWILRLPPGAKGEVPKVPMAFNDTSFSFSEDEWKNLNEWQKELYRHIMKGNYEAVISMDTAISKPDLLSRIEQGEDPNAEDQDDSEGGETPTDPSTEFFFPGPDDNSWSKYEDTLAESHYGSEEEEEEEEESMEAPNTYAQQCDEECPDSLELPGSLAGKWDDVFSNPEEELKPSSKNRSGSGPQQRGAAGNGLRRSSRRGRELSKKEAPEEMAAEEGPYICCECGQSFLDKELFAAHQRAHMDEEACTSLEAGESFRQKSKSSAKGQRSRPSKRANSEKGSGYKYGFVRPNNMVERPYTCSQCKESFSLEVSLILHQKLHTGKGDGPLTCTYCGKDFRDLSKAIRHQRIHTGERPYQCTECGKSFIRRDHLLKHWRVHTGETPYQCPVCGKHFRYKESLNCHQKIHSRNPRPMDEALQHNLESATQTSLFCLKTETKQ", "length": 564, "header": "tr|A0A8V1ADL2-1|A0A8V1ADL2_CHICK Isoform 1 of Zinc finger protein 777 OS=Gallus gallus OX=9031 GN= PE=3 SV=1 CANONICAL=A0A8V1ADL2-1" }, "isoforms": [ { "isoform_ac": "A0A8V1ADL2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADL2/entry#A0A8V1ADL2-1", "sequence": { "sequence": "MAEWAPAQDLEWAMEPQELSLEQPLAAPEEGPGREAELPAAEISVTLVTEVQAVDRKVEAQAAQLMNLEGRMRMAESKLIGCERTAVEFGNQLESKWTALGTLIQEYGQLQKRLENMENLLKNRNFWILRLPPGAKGEVPKVPMAFNDTSFSFSEDEWKNLNEWQKELYRHIMKGNYEAVISMDTAISKPDLLSRIEQGEDPNAEDQDDSEGGETPTDPSTEFFFPGPDDNSWSKYEDTLAESHYGSEEEEEEEEESMEAPNTYAQQCDEECPDSLELPGSLAGKWDDVFSNPEEELKPSSKNRSGSGPQQRGAAGNGLRRSSRRGRELSKKEAPEEMAAEEGPYICCECGQSFLDKELFAAHQRAHMDEEACTSLEAGESFRQKSKSSAKGQRSRPSKRANSEKGSGYKYGFVRPNNMVERPYTCSQCKESFSLEVSLILHQKLHTGKGDGPLTCTYCGKDFRDLSKAIRHQRIHTGERPYQCTECGKSFIRRDHLLKHWRVHTGETPYQCPVCGKHFRYKESLNCHQKIHSRNPRPMDEALQHNLESATQTSLFCLKTETKQ", "length": 564, "header": "tr|A0A8V1ADL2-1|A0A8V1ADL2_CHICK Isoform 1 of Zinc finger protein 777 OS=Gallus gallus OX=9031 GN= PE=3 SV=1 CANONICAL=A0A8V1ADL2-1" }, "locus": { "chromosome": "2", "start_pos": 598741, "end_pos": 591811, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066085.1", "url": "https://www.ensembl.org/id/ENSGALT00010066085.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040351.1", "url": "https://www.ensembl.org/id/ENSGALP00010040351.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 217, "start_aa": "Thr", "end_pos": 217, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr217", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-GGA-212436", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-212436", "resource": "Reactome", "description": "Generic Transcription Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADL2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADL2" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADL2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADL2" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADL2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADL2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADL2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADL2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADL2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADL2" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADL2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADL2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 147, "end_pos": 149, "annotation": "n_glycosylation_sequon" }, { "start_pos": 303, "end_pos": 305, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1ADL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADL2" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 345, "end_pos": 372, "start_aa": "Tyr", "end_aa": "Ala", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1ADL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADL2" }, { "id": "PS50805", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50805" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "KRAB", "eco_id": "ECO_0000259", "start_pos": 144, "end_pos": 215, "start_aa": "Met", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 217 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 147, "end_pos": 149 }, { "start_pos": 303, "end_pos": 305 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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"A0A8V1ADM8_CHICK", "mass": { "chemical_mass": 43703.0, "monoisotopic_mass": 43703.0 }, "refseq": {}, "gene_names": [ { "name": "LYRM9", "type": "recommended", "evidence": [ { "id": "A0A8V1ADM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADM8" } ] } ], "protein_names": [ { "name": "LYR motif-containing protein 9", "type": "recommended", "evidence": [ { "id": "A0A8V1ADM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADM8/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADM8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADM8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LYRM9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADM8", "locus": { "chromosome": "19", "start_pos": 9711341, "end_pos": 9744301, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029555", "url": "https://www.ensembl.org/id/ENSGALG00010029555" } ] } } ], "crossref": [ { "id": "A0A8V1ADM8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1ADM8", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd20269", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20269", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR008011", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008011", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045291", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045291", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052151", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052151", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ADM8", "url": "https://www.orthodb.org/?gene=A0A8V1ADM8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AJ14", "url": "https://www.orthodb.org/?gene=A0A8V1AJ14", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AKT0", "url": "https://www.orthodb.org/?gene=A0A8V1AKT0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AMN6", "url": "https://www.orthodb.org/?gene=A0A8V1AMN6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47061", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47061", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47061:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47061:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05347", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05347", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1ADM8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADM8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ADM8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADM8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJ14", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ14", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJ14-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ14-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AKT0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKT0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AKT0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKT0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AMN6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMN6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AMN6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMN6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMVRFDRSRGCSLYLSWGGRRWSRGLARCRRWEIWLLLPGVQHRRRRRRRRRRGRSCRGSVLLHGMDRGRGAGVQVVLRVVVVMEVRRREVREVVVMVVVVTCRCRRRTAIVSRHHFCVGCCATKRHSKKCPSTGKRLGQAVIWPSKNEICYTLKEVGFHHTRPTCENIELNGPDLLAKPHGAETPHVHEPKRRPTARGAHWGSILGRAAAVRALGTLFSREGRSVPRARRMRGRCPGTPCAGRAYPCHAHIPSERPAPPTSLPRLAHLLPPPQPTTRGVRNFSSQALKHTQHPERLKSLIMAPLPNAELVRNSLQLYRYLLRCCKQLPEENIRQHYKHAIRQSFKVHADEDDPDRIQQIIKRAIEDADWVMNKYKKQK", "length": 379, "header": "tr|A0A8V1ADM8-1|A0A8V1ADM8_CHICK Isoform 1 of LYR motif-containing protein 9 OS=Gallus gallus OX=9031 GN=LYRM9 PE=3 SV=1 CANONICAL=A0A8V1ADM8-1" }, "isoforms": [ { "isoform_ac": "A0A8V1ADM8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADM8/entry#A0A8V1ADM8-1", "sequence": { "sequence": "MMVRFDRSRGCSLYLSWGGRRWSRGLARCRRWEIWLLLPGVQHRRRRRRRRRRGRSCRGSVLLHGMDRGRGAGVQVVLRVVVVMEVRRREVREVVVMVVVVTCRCRRRTAIVSRHHFCVGCCATKRHSKKCPSTGKRLGQAVIWPSKNEICYTLKEVGFHHTRPTCENIELNGPDLLAKPHGAETPHVHEPKRRPTARGAHWGSILGRAAAVRALGTLFSREGRSVPRARRMRGRCPGTPCAGRAYPCHAHIPSERPAPPTSLPRLAHLLPPPQPTTRGVRNFSSQALKHTQHPERLKSLIMAPLPNAELVRNSLQLYRYLLRCCKQLPEENIRQHYKHAIRQSFKVHADEDDPDRIQQIIKRAIEDADWVMNKYKKQK", "length": 379, "header": "tr|A0A8V1ADM8-1|A0A8V1ADM8_CHICK Isoform 1 of LYR motif-containing protein 9 OS=Gallus gallus OX=9031 GN=LYRM9 PE=3 SV=1 CANONICAL=A0A8V1ADM8-1" }, "locus": { "chromosome": "19", "start_pos": 9744102, "end_pos": 9713905, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071440.1", "url": "https://www.ensembl.org/id/ENSGALT00010071440.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044130.1", "url": "https://www.ensembl.org/id/ENSGALP00010044130.1" } ] } }, { "isoform_ac": "A0A8V1AJ14-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADM8/entry#A0A8V1AJ14-1", "sequence": { "sequence": "MAPLPNAELVRNSLQLYRYLLRCCKQLPEENIRQHYKHAIRQSFKVHADEDDPDRIQQIIKRAIEDADWVMNKVSASDCLNFFLTQFKMKKKTLQNKL", "length": 98, "header": "tr|A0A8V1AJ14-1|A0A8V1ADM8_CHICK Computationally mapped isoform of LYR motif-containing protein 9 OS=Gallus gallus OX=9031 GN=LYRM9 PE=3 SV=1 CANONICAL=A0A8V1ADM8-1" }, "locus": { "chromosome": "19", "start_pos": 9715789, "end_pos": 9715051, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071437.1", "url": "https://www.ensembl.org/id/ENSGALT00010071437.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044127.1", "url": "https://www.ensembl.org/id/ENSGALP00010044127.1" } ] } }, { "isoform_ac": "A0A8V1AKT0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADM8/entry#A0A8V1AKT0-1", "sequence": { "sequence": "MLKSLIMAPLPNAELVRNSLQLYRYLLRCCKQLPEENIRQHYKHAIRQSFKVHADEDDPDRIQQIIKRAIEDADWVMNKYKKQK", "length": 84, "header": "tr|A0A8V1AKT0-1|A0A8V1ADM8_CHICK Computationally mapped isoform of LYR motif-containing protein 9 OS=Gallus gallus OX=9031 GN=LYRM9 PE=3 SV=1 CANONICAL=A0A8V1ADM8-1" }, "locus": { "chromosome": "19", "start_pos": 9740592, "end_pos": 9713905, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071439.1", "url": "https://www.ensembl.org/id/ENSGALT00010071439.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044129.1", "url": "https://www.ensembl.org/id/ENSGALP00010044129.1" } ] } }, { "isoform_ac": "A0A8V1AMN6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADM8/entry#A0A8V1AMN6-1", "sequence": { "sequence": "GDSRLAPLAGRRPLPPRHQRNLLSSAEARAYVPNEGWPRGVRGGVASGTAGRGRRSEGPGGLVLCCAEPPRPVSWAPAGAVRLEPSARAELKSLIMAPLPNAELVRNSLQLYRYLLRCCKQLPEENIRQHYKHAIRQSFKVHADEDDPDRIQQIIKRAIEDADWVMNKYKKQK", "length": 173, "header": "tr|A0A8V1AMN6-1|A0A8V1ADM8_CHICK Computationally mapped isoform of LYR motif-containing protein 9 OS=Gallus gallus OX=9031 GN=LYRM9 PE=3 SV=1 CANONICAL=A0A8V1ADM8-1" }, "locus": { "chromosome": "19", "start_pos": 9741938, "end_pos": 9713905, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071438.1", "url": "https://www.ensembl.org/id/ENSGALT00010071438.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044128.1", "url": "https://www.ensembl.org/id/ENSGALP00010044128.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 282, "end_pos": 284, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1ADM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADM8" }, { "id": "PF05347", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05347" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Complex 1 LYR protein", "eco_id": "ECO_0000259", "start_pos": 315, "end_pos": 369, "start_aa": "Leu", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 282, "end_pos": 284 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1ADN4-1", "uniprot_ac": "A0A8V1ADN4", "uniprot_id": "A0A8V1ADN4_CHICK", "mass": { "chemical_mass": 6606.0, "monoisotopic_mass": 6606.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "A0A8V1ADN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADN4/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADN4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADN4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADN4", "locus": {} } ], "crossref": [ { "id": "A0A8V1ADN4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1ADN4", "database": "AlphaFoldDB", "categories": [] }, { "id": "A0A8V1ADN4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADN4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ADN4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADN4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAPRSHIEKLEPLLRQYPPDLSVFEERLLGSDAGSSGGLYLLCLSQPISPCPYWTDLLM", "length": 59, "header": "tr|A0A8V1ADN4-1|A0A8V1ADN4_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=2 CANONICAL=A0A8V1ADN4-1" }, "isoforms": [ { "isoform_ac": "A0A8V1ADN4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADN4/entry#A0A8V1ADN4-1", "sequence": { "sequence": "MAPRSHIEKLEPLLRQYPPDLSVFEERLLGSDAGSSGGLYLLCLSQPISPCPYWTDLLM", "length": 59, "header": "tr|A0A8V1ADN4-1|A0A8V1ADN4_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=2 CANONICAL=A0A8V1ADN4-1" }, "locus": { "chromosome": "18", "start_pos": 1301227, "end_pos": 1300380, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071445.1", "url": "https://www.ensembl.org/id/ENSGALT00010071445.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044135.1", "url": "https://www.ensembl.org/id/ENSGALP00010044135.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1ADP2-1", "uniprot_ac": "A0A8V1ADP2", "uniprot_id": "A0A8V1ADP2_CHICK", "mass": { "chemical_mass": 34322.0, "monoisotopic_mass": 34322.0 }, "refseq": {}, "gene_names": [ { "name": "RBM8A", "type": "recommended", "evidence": [ { "id": "A0A8V1ADP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADP2" } ] } ], "protein_names": [ { "name": "RNA binding motif protein 8A", "type": "synonym", "evidence": [ { "id": "A0A8V1ADP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADP2/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADP2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADP2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RBM8A", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADP2", "locus": { "chromosome": "25", "start_pos": 803234, "end_pos": 806549, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027889", "url": "https://www.ensembl.org/id/ENSGALG00010027889" } ] } } ], "crossref": [ { "id": "A0A8V1ADP2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1ADP2", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR008111", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008111", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ADP2", "url": "https://www.orthodb.org/?gene=A0A8V1ADP2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45894", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45894", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ADP2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADP2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ADP2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADP2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGYPWGTCVCGVEAQSHRSLGCLWGIYGVFWGRNRRAAPLRGVSMGRARFCGRFDLPKMAPRALPPLSVLPKMAVPRGRVGASLTHFRRAAPPRFRRASRRAPQGGWGERGKMADVLDLHEPSGEDFAMDEDGDESIHKLKEKAKKRKGRGFGSEEGSRARVREDYDSVEQDGDEPGPQRSVEGWILFVTGVHEEATEEDRLPEGIHAGGVRDVQRGAGGHGGAERAGADGAAGQRGLVLRQRAPEGKEEGWAPAQQESGQEAPVMEPTWQQLEAGGIGGGWGGVGVGGGFGEQRSERSVQRSPWGGGMGWGAAGRPGWG", "length": 320, "header": "tr|A0A8V1ADP2-1|A0A8V1ADP2_CHICK Isoform 1 of RNA binding motif protein 8A OS=Gallus gallus OX=9031 GN=RBM8A PE=4 SV=1 CANONICAL=A0A8V1ADP2-1" }, "isoforms": [ { "isoform_ac": "A0A8V1ADP2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADP2/entry#A0A8V1ADP2-1", "sequence": { "sequence": "MGYPWGTCVCGVEAQSHRSLGCLWGIYGVFWGRNRRAAPLRGVSMGRARFCGRFDLPKMAPRALPPLSVLPKMAVPRGRVGASLTHFRRAAPPRFRRASRRAPQGGWGERGKMADVLDLHEPSGEDFAMDEDGDESIHKLKEKAKKRKGRGFGSEEGSRARVREDYDSVEQDGDEPGPQRSVEGWILFVTGVHEEATEEDRLPEGIHAGGVRDVQRGAGGHGGAERAGADGAAGQRGLVLRQRAPEGKEEGWAPAQQESGQEAPVMEPTWQQLEAGGIGGGWGGVGVGGGFGEQRSERSVQRSPWGGGMGWGAAGRPGWG", "length": 320, "header": "tr|A0A8V1ADP2-1|A0A8V1ADP2_CHICK Isoform 1 of RNA binding motif protein 8A OS=Gallus gallus OX=9031 GN=RBM8A PE=4 SV=1 CANONICAL=A0A8V1ADP2-1" }, "locus": { "chromosome": "25", "start_pos": 806350, "end_pos": 803641, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067599.1", "url": "https://www.ensembl.org/id/ENSGALT00010067599.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041342.1", "url": "https://www.ensembl.org/id/ENSGALP00010041342.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADP2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADP2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADP2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADP2" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADP2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADP2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "RNA processing", "id": "GO:0006396", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006396", 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Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052550.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015151353", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015151353" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADP5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADP5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "IFT20", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADP5", "locus": { "chromosome": "19", "start_pos": 9786322, "end_pos": 9788494, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029567", "url": "https://www.ensembl.org/id/ENSGALG00010029567" } ] } } ], "crossref": [ { "id": "A0A8V1ADP5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1ADP5", "database": 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"https://www.uniprot.org/uniprotkb/A0A8V1ADP5" } ], "pmid": "" }, { "name": "dendrite terminus", "id": "GO:0044292", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044292", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADP5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADP5" } ], "pmid": "" }, { "name": "intraciliary transport particle", "id": "GO:0030990", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030990", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADP5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADP5" } ], "pmid": "" }, { "name": "intraciliary transport particle A", "id": "GO:0030991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030991", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADP5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADP5" } ], "pmid": "" }, { "name": "kinociliary basal body", "id": "GO:1902636", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902636", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADP5", "url": 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"http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15127", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15127:SF29", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15127:SF29", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00017", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00017", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1ADP9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADP9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ADP9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADP9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AI41", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI41", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AI41-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI41-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "VQWGQPGAPGVVLHGSALALTPPPAPGGRAPGPMAAKWFKEFPSNLRTGSEKARPSKPGGTARKSLGGTEPPGGAPPGKSRKNSAAEVGGCRAAYPPGAGKDGGGRLSRDNLQGLLQAAAGRMRKNSKVEGVAAEGPPRSCGTYINRLIKVEAHEKNPKGYPSAGPAPEEKGKSPKTETVIILEDYADPYDAKRTKGQRDAERLGENDGYMEPYDAQQMITEVRRRGSKDPLVKALLLLDEAGSKAEVAKKVGGGSEAVGRGPQLYDTPYEPGADERPAAEYEQPWEWKKEQIVKALSVQFEGSERPREEAARQHLRQKSWTPRMVKPSEQSEGERVDPAVSLEKQPWYHGAITRAEAESRLQACKEAGYLVRTSESGSGKYSIALKTSQGCVHILVAQTKDHKYTLSQASGGFASVPEVVHYYSTEKLPFKGAEHMALLHPVHCKMH", "length": 448, "header": "tr|A0A8V1ADP9-1|A0A8V1ADP9_CHICK Isoform 1 of SH2 domain-containing adapter protein E OS=Gallus gallus OX=9031 GN=SHE PE=4 SV=1 CANONICAL=A0A8V1ADP9-1" }, "isoforms": [ { "isoform_ac": "A0A8V1ADP9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADP9/entry#A0A8V1ADP9-1", "sequence": { "sequence": "VQWGQPGAPGVVLHGSALALTPPPAPGGRAPGPMAAKWFKEFPSNLRTGSEKARPSKPGGTARKSLGGTEPPGGAPPGKSRKNSAAEVGGCRAAYPPGAGKDGGGRLSRDNLQGLLQAAAGRMRKNSKVEGVAAEGPPRSCGTYINRLIKVEAHEKNPKGYPSAGPAPEEKGKSPKTETVIILEDYADPYDAKRTKGQRDAERLGENDGYMEPYDAQQMITEVRRRGSKDPLVKALLLLDEAGSKAEVAKKVGGGSEAVGRGPQLYDTPYEPGADERPAAEYEQPWEWKKEQIVKALSVQFEGSERPREEAARQHLRQKSWTPRMVKPSEQSEGERVDPAVSLEKQPWYHGAITRAEAESRLQACKEAGYLVRTSESGSGKYSIALKTSQGCVHILVAQTKDHKYTLSQASGGFASVPEVVHYYSTEKLPFKGAEHMALLHPVHCKMH", "length": 448, "header": "tr|A0A8V1ADP9-1|A0A8V1ADP9_CHICK Isoform 1 of SH2 domain-containing adapter protein E OS=Gallus gallus OX=9031 GN=SHE PE=4 SV=1 CANONICAL=A0A8V1ADP9-1" }, "locus": { "chromosome": "25", "start_pos": 1949492, "end_pos": 1943715, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067609.1", "url": "https://www.ensembl.org/id/ENSGALT00010067609.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041352.1", "url": "https://www.ensembl.org/id/ENSGALP00010041352.1" } ] } }, { "isoform_ac": "A0A8V1AI41-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADP9/entry#A0A8V1AI41-1", "sequence": { "sequence": "AQGVPIVAINPSALALTPPPAPGGRAPGPMAAKWFKEFPSNLRTGSEKARPSKPGGTARKSLGGTEPPGGAPPGKSRKNSAAEVGGCRAAYPPGAGKDGGGRLSRDNLQGLLQAAAGRMRKNSKVEGVAAEGPPRSCGTYINRLIKVEAHEKNPKGYPSAGPAPEEKGKSPKTETVIILEDYADPYDAKRTKGQRDAERLGENDGYMEPYDAQQMITEVRRRGSKDPLVKALLLLDEAGSKAEVAKKVGGGSEAVGRGPQLYDTPYEPGADERPAAEYEQPWEWKKEQIVKALSVQFEGSERPREEAARQHLRQKSWTPRMVKPSEQSEGERVDPAVSLEKQPWYHGAITRAEAESRLQACKEAGYLVRTSESGSGKYSIALKTSQGCVHILVAQTKDHKYTLSQASGGFASVPEVVHYYSTEKLPFKGAEHMALLHPVHCKMH", "length": 444, "header": "tr|A0A8V1AI41-1|A0A8V1ADP9_CHICK Computationally mapped isoform of SH2 domain-containing adapter protein E OS=Gallus gallus OX=9031 GN=SHE PE=4 SV=1 CANONICAL=A0A8V1ADP9-1" }, "locus": { "chromosome": "25", "start_pos": 1949565, "end_pos": 1943715, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067611.1", "url": "https://www.ensembl.org/id/ENSGALT00010067611.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041354.1", "url": "https://www.ensembl.org/id/ENSGALP00010041354.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "phosphotyrosine residue binding", "id": "GO:0001784", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001784", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADP9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADP9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1ADP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADP9" }, { "id": "PS50001", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50001" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SH2", "eco_id": "ECO_0000259", "start_pos": 348, "end_pos": 443, "start_aa": "Trp", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1ADQ4-1", "uniprot_ac": "A0A8V1ADQ4", "uniprot_id": "A0A8V1ADQ4_CHICK", "mass": { "chemical_mass": 36455.0, "monoisotopic_mass": 36455.0 }, "refseq": { "ac": "XP_024999342", "name": "LIX1-like protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024999342" }, "gene_names": [ { "name": "LOC107051565", "type": "recommended", "evidence": [ { "id": "A0A8V1ADQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADQ4" } ] }, { "name": "LOC107051565", "type": "synonym", "evidence": [ { "id": "XP_024999342", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024999342" } ] } ], "protein_names": [ { "name": "LIX1-like protein", "type": "synonym", "evidence": [ { "id": "XP_024999342", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024999342" } ] }, { "name": "Limb and CNS expressed 1 like", "type": "synonym", "evidence": [ { "id": "A0A8V1ADQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADQ4/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052556.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_024999342.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_024999342", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024999342" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADQ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADQ4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC107051565", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADQ4", "locus": {} } ], "crossref": [ { "id": "A0A8V1ADQ4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1ADQ4", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00048", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00048", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "107051565", "url": "https://www.ncbi.nlm.nih.gov/gene/107051565", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR029270", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029270", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051436", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051436", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:107051565", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:107051565", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MDWVSRE", "url": "https://omabrowser.org/oma/group/MDWVSRE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ADQ4", "url": "https://www.orthodb.org/?gene=A0A8V1ADQ4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31139", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31139", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31139:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31139:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14954", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14954", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_024999342", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024999342", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1ADQ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADQ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ADQ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADQ4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MESVRAQRLQPGVGGTLRSLRPGVTGAPAAPPPAAAPPPPAVLGPGLGLPPPPPPLGLQGSAASAPPPPPGSGPPAVLREAVEAVVRSFAKHTQGYGRVNVVEALQEFWQMKQSRGADLKNGALVVYEMVPANSPPYVCYVTLPGGSCFGSFQFCPTKAEARRSAAKIALMNSVFNEHPSRRITDEFIEKSVSEALASFNGNQEEADNPNTGIGAFRFMLESNKGKSMLEFQELMTVFQLLHWNGSLKAMRERQCSRQEVLAHYSHRALDDDIRQQMAMDWVSREQSSPGALSRELAATERELDEARLAGKELRFHKERKDILLLAAGQLGSLHSSGC", "length": 338, "header": "tr|A0A8V1ADQ4-1|A0A8V1ADQ4_CHICK Isoform 1 of Limb and CNS expressed 1 like OS=Gallus gallus OX=9031 GN=LOC107051565 PE=3 SV=1 CANONICAL=A0A8V1ADQ4-1" }, "isoforms": [ { "isoform_ac": "A0A8V1ADQ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADQ4/entry#A0A8V1ADQ4-1", "sequence": { "sequence": "MESVRAQRLQPGVGGTLRSLRPGVTGAPAAPPPAAAPPPPAVLGPGLGLPPPPPPLGLQGSAASAPPPPPGSGPPAVLREAVEAVVRSFAKHTQGYGRVNVVEALQEFWQMKQSRGADLKNGALVVYEMVPANSPPYVCYVTLPGGSCFGSFQFCPTKAEARRSAAKIALMNSVFNEHPSRRITDEFIEKSVSEALASFNGNQEEADNPNTGIGAFRFMLESNKGKSMLEFQELMTVFQLLHWNGSLKAMRERQCSRQEVLAHYSHRALDDDIRQQMAMDWVSREQSSPGALSRELAATERELDEARLAGKELRFHKERKDILLLAAGQLGSLHSSGC", "length": 338, "header": "tr|A0A8V1ADQ4-1|A0A8V1ADQ4_CHICK Isoform 1 of Limb and CNS expressed 1 like OS=Gallus gallus OX=9031 GN=LOC107051565 PE=3 SV=1 CANONICAL=A0A8V1ADQ4-1" }, "locus": { "chromosome": "25", "start_pos": 825298, "end_pos": 809263, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067614.1", "url": "https://www.ensembl.org/id/ENSGALT00010067614.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041357.1", "url": "https://www.ensembl.org/id/ENSGALP00010041357.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:107051565", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:107051565", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8M2B6G9-1", "protein_name": "LIX1-like protein isoform X1", "gene_name": "lix1l", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MESLRHQRLQPGIGYGASATGTLRSLRPGVTGTLSSAQGSHVSVSASPGPPPPPPPLQLHSLGSSFMGSGFGSVDMAAGLGLSNPTNPAVLREAVDAVVRSFAKHTQGYGRVNVVEALQEFWQMKQSRGADLRNGALVVYEMVPSNNPPYVCYVSLPGGSCFGSFQFCPTKAEARRSAAKIALMNSVFNEHPSRRITDDFIEKSVCEALASFNGNREEADNPSTGIGAFRFMLESNKGKSMLEFQELMTVFQLLHWNGSLKAMRERQCSRQEVLAHYSHRALDDDMRTQMAADWVSREHTLSGTINREMAATERELEEARLAGRELRFYKEKKDILLMAVGQLGGSNTTTLPCTC", "length": 355 }, "evidence": [ { "id": "A0A8V1ADQ4", "url": "https://omabrowser.org/oma/group/A0A8V1ADQ4/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "I3LS88-1", "protein_name": "Limb and CNS expressed 1 like", "gene_name": "LIX1L", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "METLRAQRLQPGVGTSGRGTLRALRPGVTGAAAATATPPAGPPPAPPPPAPPPPPLLLSGAAGLPMPPGAAGSPAVLREAVEAVVRSFAKHTQGYGRVNVVEALQEFWQMKQSRGADLKNGALVVYEMVPSNSPPYVCYVTLPGGSCFGSFQFCPTKAEARRSAAKIALMNSVFNEHPSRRITDEFIEKSVSEALASFNGNREEADNPNTGIGAFRFMLESNKGKSMLEFQELMTVFQLLHWNGSLKAMRERQCSRQEVLAHYSHRALDDDIRHQMALDWVSREQSVPGALSRELASTERELDEARLAGKELRFHKEKKDILMLAAGQLGNMHSSNC", "length": 337 }, "evidence": [ { "id": "A0A8V1ADQ4", "url": "https://omabrowser.org/oma/group/A0A8V1ADQ4/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q5PQQ7-1", "protein_name": "LIX1-like protein", "gene_name": "Lix1l", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "METMRAQRLQPGVGVGGRGTLRALRPGVTGAPTSAATPPAGPPPAPPPPAPPPPPLLLAGAPGLPLPPGATGSPAVLREAVEAVVRSFAKHTQGYGRAVNVVEALQEFWQMKQSRGADLKNGALVVYEMVPSNSPPYVCYVTLPGGSCFGSFQFCPTKAEARRSAAKIALMNSVFNEHPSRRITDEFIEKSVSEALASFNGNREEADNPNTGIGAFRFMLESNKGKSMLEFQELMTVFQLLHWNGSLKAMRERQCSRQEVLAHYSHRALDDDIRHQMALDWVSREQSVPGALSRELASTERELDEARLAGKELRFHKEKKDILMLAAGQLGNMHSSSC", "length": 338 }, "evidence": [ { "id": "A0A8V1ADQ4", "url": "https://omabrowser.org/oma/group/A0A8V1ADQ4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8BQ89-1", "protein_name": "LIX1-like protein", "gene_name": "Lix1l", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "METMRAQRLQPGVGVGGRGTLRALRPGVTGAPTSAATPPVGPPPAPPPPAPPLPPLLLAGAPGLPLPPGAAGSPAVLREAVEAVVRSFAKHTQGYGRVNVVEALQEFWQMKQSRGADLKNGALVVYEMVPSNSPPYVCYVTLPGGSCFGSFQFCPTKAEARRSAAKIALMNSVFNEHPSRRITDEFIEKSVSEALASFNGNREEADNPNTGIGAFRFMLESNKGKSMLEFQELMTVFQLLHWNGSLKAMRERQCSRQEVLAHYSHRALDDDIRHQMALDWVSREQSVPGALSRELASTERELDEARLAGKELRFHKEKKDILMLAAGQLGNMHSSSC", "length": 337 }, "evidence": [ { "id": "A0A8V1ADQ4", "url": "https://omabrowser.org/oma/group/A0A8V1ADQ4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8IVB5-1", "protein_name": "LIX1-like protein", "gene_name": "LIX1L", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METMRAQRLQPGVGTSGRGTLRALRPGVTGAAAATATPPAGPPPAPPPPAPPPPPLLLSGAPGLPLPPGAAGSPAVLREAVEAVVRSFAKHTQGYGRVNVVEALQEFWQMKQSRGADLKNGALVVYEMVPSNSPPYVCYVTLPGGSCFGSFQFCPTKAEARRSAAKIALMNSVFNEHPSRRITDEFIEKSVSEALASFNGNREEADNPNTGIGAFRFMLESNKGKSMLEFQELMTVFQLLHWNGSLKAMRERQCSRQEVLAHYSHRALDDDIRHQMALDWVSREQSVPGALSRELASTERELDEARLAGKELRFHKEKKDILVLAAGQLGNMHSSNC", "length": 337 }, "evidence": [ { "id": "A0A8V1ADQ4", "url": "https://omabrowser.org/oma/group/A0A8V1ADQ4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "autophagosome maturation", "id": "GO:0097352", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097352", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADQ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADQ4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADQ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADQ4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 244, "end_pos": 246, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 244, "end_pos": 246 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1ADR0-1", "uniprot_ac": "A0A8V1ADR0", "uniprot_id": "A0A8V1ADR0_CHICK", "mass": { "chemical_mass": 58562.0, "monoisotopic_mass": 58562.0 }, "refseq": { "ac": "XP_422860", "name": "protein misato homolog 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_422860" }, "gene_names": [ { "name": "MSTO1", "type": "recommended", "evidence": [ { "id": "A0A8V1ADR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADR0" } ] }, { "name": "MSTO1", "type": "synonym", "evidence": [ { "id": "XP_422860", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_422860" } ] } ], "protein_names": [ { "name": "Protein misato homolog 1", "type": "recommended", "evidence": [ { "id": "A0A8V1ADR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADR0/entry#names_and_taxonomy" } ] }, { "name": "protein misato homolog 1", "type": "synonym", "evidence": [ { "id": "XP_422860", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_422860" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052556.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_422860.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_422860", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_422860" } ] }, { "annotation": "Involved in the regulation of mitochondrial distribution and morphology. Required for mitochondrial fusion and mitochondrial network formation.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADR0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADR0#function" }, { "database": "UniProtKB", "id": "ARBA00045225", "url": "https://www.uniprot.org/uniprotkb/ARBA00045225#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADR0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADR0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MSTO1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADR0", "locus": { "chromosome": "25", "start_pos": 2180338, "end_pos": 2176814, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028433", "url": "https://www.ensembl.org/id/ENSGALG00010028433" } ] } } ], "crossref": [ { "id": "A0A8V1ADR0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1ADR0", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd06060", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06060", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "425066", "url": "https://www.ncbi.nlm.nih.gov/gene/425066", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019605", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019605", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029209", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029209", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036525", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036525", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049942", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049942", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:425066", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:425066", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RMAAYGC", "url": "https://omabrowser.org/oma/group/RMAAYGC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ADR0", "url": "https://www.orthodb.org/?gene=A0A8V1ADR0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13391", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13391", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13391:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13391:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10644", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10644", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14881", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14881", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_422860", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_422860", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1ADR0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADR0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ADR0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADR0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAGEVVTLQLGHYAGCVGAHWWGLQRCPPEGTELSHAALLRAGRDGCTPRLIALELKGGVGPLGRGGARPEPLAAWRGDVANYAEPGTGTALRDRGQRPGDASADADCGSGAPGEGAAPSAGSSTQLWSDYLSVQLHPRSIYVLQQYNHDGDSGRLEAFGQGEKLLQDASCMEELEDRLHFYAEECDYLQGFQVLCDLHDGFSGVGAKVTEVLQDEYSRKGILTWGLTPVTHTVADSQKNFYRVLNAALGIVHLSAHSSLFCPLSLSGSLGIKPQPPIEFPYVNYDASLNYHSSAVLAAALDTLTVPYRLCSSRGSMMHLAEMLSFSGRKVVAAWAAVPFPAVRGHSLPDALCAHQQDVPWKLLSSCKEQKVSRCFAQSVVLRGVCKESPTSCPGQQPPSPLHACETAEQVLQYYLHTAFPGAFSASHVLEQPCVTLPPYPRIFSPLLSRQGFLPDDLSSYSAAAVESIPVLTSLQSSPVLRTLLCDLCKDLQKLGTRRCASFFAAGVEEDDFHEALQELRTLSQCYQMGFEADNSEDESDSD", "length": 543, "header": "tr|A0A8V1ADR0-1|A0A8V1ADR0_CHICK Isoform 1 of Protein misato homolog 1 OS=Gallus gallus OX=9031 GN=MSTO1 PE=1 SV=1 CANONICAL=A0A8V1ADR0-1" }, "isoforms": [ { "isoform_ac": "A0A8V1ADR0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADR0/entry#A0A8V1ADR0-1", "sequence": { "sequence": "MAGEVVTLQLGHYAGCVGAHWWGLQRCPPEGTELSHAALLRAGRDGCTPRLIALELKGGVGPLGRGGARPEPLAAWRGDVANYAEPGTGTALRDRGQRPGDASADADCGSGAPGEGAAPSAGSSTQLWSDYLSVQLHPRSIYVLQQYNHDGDSGRLEAFGQGEKLLQDASCMEELEDRLHFYAEECDYLQGFQVLCDLHDGFSGVGAKVTEVLQDEYSRKGILTWGLTPVTHTVADSQKNFYRVLNAALGIVHLSAHSSLFCPLSLSGSLGIKPQPPIEFPYVNYDASLNYHSSAVLAAALDTLTVPYRLCSSRGSMMHLAEMLSFSGRKVVAAWAAVPFPAVRGHSLPDALCAHQQDVPWKLLSSCKEQKVSRCFAQSVVLRGVCKESPTSCPGQQPPSPLHACETAEQVLQYYLHTAFPGAFSASHVLEQPCVTLPPYPRIFSPLLSRQGFLPDDLSSYSAAAVESIPVLTSLQSSPVLRTLLCDLCKDLQKLGTRRCASFFAAGVEEDDFHEALQELRTLSQCYQMGFEADNSEDESDSD", "length": 543, "header": "tr|A0A8V1ADR0-1|A0A8V1ADR0_CHICK Isoform 1 of Protein misato homolog 1 OS=Gallus gallus OX=9031 GN=MSTO1 PE=1 SV=1 CANONICAL=A0A8V1ADR0-1" }, "locus": { "chromosome": "25", "start_pos": 2180262, "end_pos": 2176853, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068865.1", "url": "https://www.ensembl.org/id/ENSGALT00010068865.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042307.1", "url": "https://www.ensembl.org/id/ENSGALP00010042307.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:425066", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:425066", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6AIT8-1", "protein_name": "Misato mitochondrial distribution and morphology regulator 1", "gene_name": "Msto1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "RGPRLPWSAQELRRHGGRGPRGAHAAVGTFRGFRRGALVEPAGCCVGTHDRGRRVARRAVPGRLVSKWPDTAWPGNLYTSTHPHGPQSLNTLKEEGSLYRDRQLEAAIAWQGKLTTHREEANSKNPNLQDLLSAEGVLSSDGALRAKLIQNGKENSIKVWSDFLRVHLHPRSICVIQKYNHDGETGRLEAFGQGESVLKEPRYLEELEDRLHFYVEECDYLQGFQILCDLHDGFSGVGAKTAELLQDEYSGRGVLTWGLLPGPYSLGEPQKNIYRLLNTAFGLVHLAGYSSFVCPLSLGGNLGLRPKPPVNFPYLHYDATLPFHCSAILATALDTVTVPYRLRSSTVSMAHLADVLSFSGKKVVTAEAIIPFPLVRGQSLPDILMQLGEATPWTSLSACGDSAGHRCFAQSVVLRGIDRASHTSKLNPGTPLPSTLHACASGEEVLAQYLEQQHPRVLSSSYLLLTPCKMAPPYPHFFSSFSQKGLAMDGAPKGAAVQSIPVFGALRSTSSLQRTLRDLGDELARLDLRRWASFMDAGVEQDDMEELLQELHSLAHLDSGPPSWQGQEPSLAASGHSDSYNRQQLD", "length": 586 }, "evidence": [ { "id": "A0A8V1ADR0", "url": "https://omabrowser.org/oma/group/A0A8V1ADR0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A5D9D4-1", "protein_name": "Protein misato homolog 1", "gene_name": "MSTO1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAGGAREVLTLQLGHFAGFVGAHWWNQQDAALCRPTDAKEPPGELCPDVLYRTGRTLHGQETYTPRLILMDLKGSLSSLKQEGGLYRDKQLDAAIAWQGKLTTHKEELYPKNPYLQDLLSAEGVLSSDGTWRVKSIPNGKGLPPFTNAITPKPVMPTEGSIRVWSDFLRVHLHPRSICMIHKYNHDGEAGRLEAFGQGESILKEPKYLEELEDRLHFYVEECDYLQGFQILCDLHDGFSGLGAKAAELLQDEYSGRGIITWGLLPGPYRLGELQKNIYRLLNTAFGLVHLSAHSSLVCPLSLGGSLGLRPEPPVSFPLLQYDATLPFHCGAILATALDTVTVPYRLRSSPVSMVHLADMLNFSGKKVVTAGATIPFPSVPSQSLPDTLMQLGEATPWTPLSACGDPSGTCCFAQSVVLRGLDRAHHTSQLAPGTPLPSPLHACATGEEVLAQYLQQQQPRVRSSSHLLLTPCKVVPPYPSLFSSSLSQHGSVLDGLPTGTAVESIPVLGALCSSSSLNRALGDLAKDLSKLDLRRWASFMDAGVEQDDLEETLQDLRSLAQCYEGGDDRLVD", "length": 572 }, "evidence": [ { "id": "A0A8V1ADR0", "url": "https://omabrowser.org/oma/group/A0A8V1ADR0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "O01939-1", "protein_name": "Protein misato", "gene_name": "mst", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDYTREILTFQFGTYANYVGTHFWNQQEANFRYGDESEQVAEEQLPNNDILYREGRNDLNRTTYTPRLLSVDLSGTLGHLPVTGELYGNFVQRDEELLPLSTGEELEQVRKRAEESGVCSPEQLEVQEQSKASISEYQRDLLKNAVVPEKNYQLAATANSWVDFLYARYHPRTLNVLPGLIRDPTAQALGTYSAGTEMWQEVSFNEEFCDRIRLYVEECDGLQGFHVLFDIDDGFGGLAGKCLEHLNDEYSRASFALPLHYPRITSYPQADTRLSHSIRVVNNVLGYHQLSEQALMFTPLSTLETIWRNNNLKSRSLPGLQWETDNLYQTSALLAAFFDTATLSYRLRQTPESLLRFCECVTPAGRKMTAAGLALPFGLREGQDLIEFLDQSGDHALLTQLTPGCEPGTSYVVQSVTARGIPAERLKRPRELAGDQLRMAAYSCDSISHMLQLYYQCTYHGSVTNAAATPLPLKTQLPFPYEMFAAGISRDGYRLPEGAERETGSRVDSAPMLAAVQNSTKLGEHLDNVHAQSHRVQLAKLQAYSNSGLERDEYDTALDQLLEFRDLYADSQYL", "length": 574 }, "evidence": [ { "id": "A0A8V1ADR0", "url": "https://omabrowser.org/oma/group/A0A8V1ADR0/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q1L908-1", "protein_name": "Protein misato homolog 1", "gene_name": "msto1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSGACREVVTLQLGHYSNFIGTHWWNLQDAGLVYDADVPAGELQSDVLFREGLTLAGHVTYTPRLIAIDLKGSLQTLRKEGSLYDTENENSAFTWDGQIMTHQESPPSKNSFLQELDNLDTGGVLAESDFNHLTSSVDNCSVPGASVAVETINSSLERIQKSYRLEGSVRVWSDFLRLHLHPRTISVINQYNHDGESERLEVFGQGEALLQGQVLEDLEDRLHFFIEECDYLQGFQVLCDLTDGFSGLGSKVTEYLQDSYGGRGILTWGVAPVNHPDTSSMKDLYHMMNCALGTLQMANHSSLFCPLTLRGGLCRRPPPPTAFPLLNCDPLLWYHSSSVLALALDALTVSYRMRHCSATMWQLSDALTTSGRKVVSAYGSVPFPMMLGGCLPDALDAFSNAVPWRSLSACPEISDRRFCFSQSVTLKGVDEQSLVSRLLPGMEAPSPLHYERSGEDVLSAYVRSHYPSSPLAVQLVSSGSKVTPPFPQIFSPSLSAQGFLQSHSTPASPSCPPVSCLPVLTSLQSSPAVGLQLSELQRACASLDLRRVAPSFLTHGPEHAEISEYLEQLRNLAHCYRQSHSRSSSEEDDDD", "length": 591 }, "evidence": [ { "id": "A0A8V1ADR0", "url": "https://omabrowser.org/oma/group/A0A8V1ADR0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q2YDW2-1", "protein_name": "Protein misato homolog 1", "gene_name": "Msto1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAGGAREVLTLQLGHFAGFVGAHWWNQQDAALGRMAEDEESPGELCPDVLYRTGRTLHGQETYTPRLILMDLKGSLNTLKEEGNLYRDRQLEAAVAWQGKLSTHREDAHPKNPNLQGLLSAEGVRSSDGAWRAKLIQNIQNGKENSIKVWSDFLRVHLHPRSICVIHKYHHDGETGRLEAFGQGESVLKEPRYLEELEDRLHFYVEECDYLQGFQLLCDLHDGFSGVGAKTAELLQDEYAGRGVLTWGLLPGPYSLGEPQKNIYRLLNTAFGLVHLTGYSSFVCPLSLGGNLGLRPKPPVNFPSLHYDATLPFHCSAILATALDTVTVPYRLRSSMVTMAHLADVLSFSGKKVVTAEAIIPFPLVRGQSLPDILTQLGEATPWTSLSACGDSAGHRCFAQSVVLRGIDRASHTSKLNPGTPLPSALHACASGEEVLAQYLQQQHPRVLSSSHLLLTPCKVAPPYPHFFSSFSQKGLAMDSTPKGAAVQSIPVFGALRSTSSLHRTLGDLAEELSRLDLRRWASFMDAGVEQDDMEEMLHELHRLAQCYQEGDSLSN", "length": 556 }, "evidence": [ { "id": "A0A8V1ADR0", "url": "https://omabrowser.org/oma/group/A0A8V1ADR0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9BUK6-1", "protein_name": "Protein misato homolog 1", "gene_name": "MSTO1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAGGAREVLTLQLGHFAGFVGAHWWNQQDAALGRATDSKEPPGELCPDVLYRTGRTLHGQETYTPRLILMDLKGSLSSLKEEGGLYRDKQLDAAIAWQGKLTTHKEELYPKNPYLQDFLSAEGVLSSDGVWRVKSIPNGKGSSPLPTATTPKPLIPTEASIRVWSDFLRVHLHPRSICMIQKYNHDGEAGRLEAFGQGESVLKEPKYQEELEDRLHFYVEECDYLQGFQILCDLHDGFSGVGAKAAELLQDEYSGRGIITWGLLPGPYHRGEAQRNIYRLLNTAFGLVHLTAHSSLVCPLSLGGSLGLRPEPPVSFPYLHYDATLPFHCSAILATALDTVTVPYRLCSSPVSMVHLADMLSFCGKKVVTAGAIIPFPLAPGQSLPDSLMQFGGATPWTPLSACGEPSGTRCFAQSVVLRGIDRACHTSQLTPGTPPPSALHACTTGEEILAQYLQQQQPGVMSSSHLLLTPCRVAPPYPHLFSSCSPPGMVLDGSPKGAAVESIPVFGALCSSSSLHQTLEALARDLTKLDLRRWASFMDAGVEHDDVAELLQELQSLAQCYQGGDSLVD", "length": 570 }, "evidence": [ { "id": "A0A8V1ADR0", "url": "https://omabrowser.org/oma/group/A0A8V1ADR0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "positive regulation of mitochondrial fusion", "id": "GO:0010636", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010636", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADR0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADR0" } ], "pmid": "" }, { "name": "mitochondrion organization", "id": "GO:0007005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007005", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADR0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADR0" } ], "pmid": "" }, { "name": "mitochondrion distribution", "id": "GO:0048311", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048311", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADR0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADR0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADR0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADR0" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADR0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADR0" } ], "pmid": "" }, { "name": "mitochondrial outer membrane", "id": "GO:0005741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005741", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADR0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADR0" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADR0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADR0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1ADR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADR0" }, { "id": "PF14881", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14881" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DML1/Misato tubulin", "eco_id": "ECO_0000259", "start_pos": 122, "end_pos": 310, "start_aa": "Gly", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1ADR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADR0" }, { "id": "PF10644", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10644" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Misato Segment II tubulin-like", "eco_id": "ECO_0000259", "start_pos": 4, "end_pos": 68, "start_aa": "Glu", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1ADR8-1", "uniprot_ac": "A0A8V1ADR8", "uniprot_id": "A0A8V1ADR8_CHICK", "mass": { "chemical_mass": 245473.0, "monoisotopic_mass": 245473.0 }, "refseq": { "ac": "XP_015154141", "name": "GON-4-like protein isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015154141" }, "gene_names": [ { "name": "GON4L", "type": "recommended", "evidence": [ { "id": "A0A8V1ADR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADR8" } ] }, { "name": "GON4L", "type": "synonym", "evidence": [ { "id": "XP_015154141", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015154141" } ] } ], "protein_names": [ { "name": "GON-4-like protein", "type": "recommended", "evidence": [ { "id": "A0A8V1ADR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADR8/entry#names_and_taxonomy" } ] }, { "name": "GON-4 homolog", "type": "synonym", "evidence": [ { "id": "A0A8V1ADR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADR8/entry#names_and_taxonomy" } ] }, { "name": "GON-4-like protein isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015154141", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015154141" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052556.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015154141.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015154141", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015154141" } ] }, { "annotation": "Acts as a key transcription regulator of histones. Activates transcription of the histone H2A, histone H2B, histone H3 and histone H4 genes in conjunction with GON4L and MIZF. Together with CRAMP1, binds to the promoters of H1 genes (H1-2, H1-3, H1-4, H1-5 and H1-10/H1x), driving their transcription. Also acts as a transcription corepressor, as part of a complex with YY1, SIN3A and HDAC1. Required for B-cell lymphopoiesis.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADR8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADR8#function" }, { "database": "UniProtKB", "id": "ARBA00094466", "url": "https://www.uniprot.org/uniprotkb/ARBA00094466#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADR8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADR8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "GON4L", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADR8", "locus": {} } ], "crossref": [ { "id": "cd12202", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12202", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "425067", "url": "https://www.ncbi.nlm.nih.gov/gene/425067", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003822", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003822", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036600", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036600", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049257", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049257", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052435", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052435", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "HRNYKDC", "url": "https://omabrowser.org/oma/group/HRNYKDC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ADR8", "url": "https://www.orthodb.org/?gene=A0A8V1ADR8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16088", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16088", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16088:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16088:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02671", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02671", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21227", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21227", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015154141", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015154141", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1ADR8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADR8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ADR8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADR8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MALSLKMLPCKKRRAAAAGPHSPRERSGSGEDGEPPPPQPPPPPPAAASSAVAAAVWRTPAEALPRGGRRPPQEGNEGRPGAAEPCAAPPERGEDAKRLEGGKEGKTPKLHTEVEANVQRDLCLTDNPSAVQESPSRSNLQLAVRSPAAVKLLKSTRPEEQDGEDIERRKRRRKANKRKREGKSQEEERTLSCDIKLDDTLDRTLEDGAKQHNLTVVNVRNILHEVITNEHVVAMMKAAISETEDIPLFEPKMTRSKLKEVVEKGVVIPTWNISPIKKANEVKPPQFVDIPLEEDDSSDEEYQPDDEDEDETAEESLLESDVESTASSPRGAKRSRTRRSSDEEGGALCEVEKVPTPVVRHISAEVVPMGPPPPPKPKQSKDSTFMEKLHAVDEELASSPVCMDSYQPLEDSLIAFRTRSKRPLKDVPLGQLEAELRAPDITPDMYDPNTADDEEWKRWLGGLMNDDVENEDELDDDDDPEYNFLEDLDEPDTEDFRNDRAVRITKKEVNELMEELFETFQDEMGFSNMEDEGPEDEDNVTESRPNFNTPQALRFEEPLANLLNEQHRTVKEQLEQLRMKKSSIKPPQEAEKAKPQNEKPLQSLVLDCAQRKRLQQQMQQHVQLLTQIHLLASSNPALSSEASTTKMFLSELGNFARSSTLLRQSFYPKFQTMFQPCNLKGALQLVEDFHAQVQVDCSPRKAVKKSASDFPCLPKQVAWILATRRVFMYPELLPICSLKANPPRDKIIFTKAEDNLLALGLKHFEGTEFPKPLISKYLLPTKTAHQLTVRIKNLNMNRAPDNIIRHYKKTKQLPVLFKCCDEIQPNEWKPPVEREEHRLPFWLKASLPSIQGELKQLAEDAREVPGSTDEESDFLGTEKETSDTECGEKYPLLMPKGLVLTLKPLANRFSRRAWRRQKSSALKPVLIRPSPCLQPSSNTVNIQKTVKLSQSEAPPGKVMVQIPQLIQPATVVQAVPGVQPLNVPAVVGSGDGLEFQNVLSASHPDSRQGFSGAVPPALVSSSPVTFQPKLMLPDLAGTKIRKPCVRKVYQKKKGTKAAPLIKAPPLIQPSPVILTVPATTVKVVNIGNGCNMIQSINTAVGRGTQAIPVTTLLVNPSTFPCPLNQPLVTSSIPSLIVSPNPVGLSAPSVAESEEQLNLLPSCPAGNNKNSCPVVEPKAEPQELCVPCSAASPKKECSANPTASNNTSQEKVNKSDCCSWTMVKAEENVSEPLSVDLLPHLEDSDKTVKSEAEDSNDAVKEVNPVQKRNLLCVEVKEEFMLGLGQELNMEAACSCANELKEIKKEHALCEEKGGEEERRALQSSPRDEPQREAGAVGGAQACSESPKNHSSSVDVEAEFSSPLGRPEDSSSMDGQSVGTPAGPEAGGEREGQEEEEDDDFDDFTQDEDEEMSSASEESILSVPELQETMEKLTWLATERRLSQEGDSEEENSQEENSEPEEEEEEEGEGMESSQKDDEVCGDVSEEPKSAFTLTNMAPQVEAHRMPPGENMKAPGKSRSSHRARNKRGRARASKDTSKLLLLYDENILERDPLREQKDLAFAQAYLTRVREALQHIPGKYEDFLRVIYEFEISMDKQTAVDLYFTLQKLLHDWPQLLTDFAAFLLPEQALECGLFEEQQAFEKSRKFLRQLEICFAENPAHHQKIIKVLQSSVDCLPQEIAELKTQMWQLLKGHDHLQDEFSVFFDHLRPSASRMGDFEEINWTEEKEYEFDGFEEVSLPDVEEEDEPPKIHAAPKNKKRKEIGGQNNDKEAEWGDAMKECSCSCHEGSGELKLKKSKRRSCSHCSSKVCENKFYKNKDSQELSASLVQQESSPQPEGKDSGTSKEPAEENLENRDEGEDVQSRTRTVSRKGEPLPAGSQPEGRAVCSRHTSPDKAALPERRVQEGGVSAAKDSPFVAVPGWTRLQKAAPKLPQETKGSPCSAGSGSEGLKQQHQGDVDASLELSRDLLLSSRSATVKGSMRPGSSKNSLCQTEGLPSDSSDKFGHSSKLSAREFEGSPLPLEGKSEAKQSWITPARKPALGKSCCSPSPSNCALEADSMGCTGSVPENRLKSNANNCFQVHRHSEELEYRVCTASLGQKEEEQQQQRVTEATVCAKNSKVSSTGEKVVLWTREADRVILTTCQEKGAHLETFQAISQKLGNKTAAEVSHRFRELMKLFHTSCDGSSEDEEDATSTSNADQLSDKDLLLSEEEPDD", "length": 2215, "header": "tr|A0A8V1ADR8-1|A0A8V1ADR8_CHICK Isoform 1 of GON-4-like protein OS=Gallus gallus OX=9031 GN=GON4L PE=4 SV=1 CANONICAL=A0A8V1ADR8-1" }, "isoforms": [ { "isoform_ac": "A0A8V1ADR8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADR8/entry#A0A8V1ADR8-1", "sequence": { "sequence": "MALSLKMLPCKKRRAAAAGPHSPRERSGSGEDGEPPPPQPPPPPPAAASSAVAAAVWRTPAEALPRGGRRPPQEGNEGRPGAAEPCAAPPERGEDAKRLEGGKEGKTPKLHTEVEANVQRDLCLTDNPSAVQESPSRSNLQLAVRSPAAVKLLKSTRPEEQDGEDIERRKRRRKANKRKREGKSQEEERTLSCDIKLDDTLDRTLEDGAKQHNLTVVNVRNILHEVITNEHVVAMMKAAISETEDIPLFEPKMTRSKLKEVVEKGVVIPTWNISPIKKANEVKPPQFVDIPLEEDDSSDEEYQPDDEDEDETAEESLLESDVESTASSPRGAKRSRTRRSSDEEGGALCEVEKVPTPVVRHISAEVVPMGPPPPPKPKQSKDSTFMEKLHAVDEELASSPVCMDSYQPLEDSLIAFRTRSKRPLKDVPLGQLEAELRAPDITPDMYDPNTADDEEWKRWLGGLMNDDVENEDELDDDDDPEYNFLEDLDEPDTEDFRNDRAVRITKKEVNELMEELFETFQDEMGFSNMEDEGPEDEDNVTESRPNFNTPQALRFEEPLANLLNEQHRTVKEQLEQLRMKKSSIKPPQEAEKAKPQNEKPLQSLVLDCAQRKRLQQQMQQHVQLLTQIHLLASSNPALSSEASTTKMFLSELGNFARSSTLLRQSFYPKFQTMFQPCNLKGALQLVEDFHAQVQVDCSPRKAVKKSASDFPCLPKQVAWILATRRVFMYPELLPICSLKANPPRDKIIFTKAEDNLLALGLKHFEGTEFPKPLISKYLLPTKTAHQLTVRIKNLNMNRAPDNIIRHYKKTKQLPVLFKCCDEIQPNEWKPPVEREEHRLPFWLKASLPSIQGELKQLAEDAREVPGSTDEESDFLGTEKETSDTECGEKYPLLMPKGLVLTLKPLANRFSRRAWRRQKSSALKPVLIRPSPCLQPSSNTVNIQKTVKLSQSEAPPGKVMVQIPQLIQPATVVQAVPGVQPLNVPAVVGSGDGLEFQNVLSASHPDSRQGFSGAVPPALVSSSPVTFQPKLMLPDLAGTKIRKPCVRKVYQKKKGTKAAPLIKAPPLIQPSPVILTVPATTVKVVNIGNGCNMIQSINTAVGRGTQAIPVTTLLVNPSTFPCPLNQPLVTSSIPSLIVSPNPVGLSAPSVAESEEQLNLLPSCPAGNNKNSCPVVEPKAEPQELCVPCSAASPKKECSANPTASNNTSQEKVNKSDCCSWTMVKAEENVSEPLSVDLLPHLEDSDKTVKSEAEDSNDAVKEVNPVQKRNLLCVEVKEEFMLGLGQELNMEAACSCANELKEIKKEHALCEEKGGEEERRALQSSPRDEPQREAGAVGGAQACSESPKNHSSSVDVEAEFSSPLGRPEDSSSMDGQSVGTPAGPEAGGEREGQEEEEDDDFDDFTQDEDEEMSSASEESILSVPELQETMEKLTWLATERRLSQEGDSEEENSQEENSEPEEEEEEEGEGMESSQKDDEVCGDVSEEPKSAFTLTNMAPQVEAHRMPPGENMKAPGKSRSSHRARNKRGRARASKDTSKLLLLYDENILERDPLREQKDLAFAQAYLTRVREALQHIPGKYEDFLRVIYEFEISMDKQTAVDLYFTLQKLLHDWPQLLTDFAAFLLPEQALECGLFEEQQAFEKSRKFLRQLEICFAENPAHHQKIIKVLQSSVDCLPQEIAELKTQMWQLLKGHDHLQDEFSVFFDHLRPSASRMGDFEEINWTEEKEYEFDGFEEVSLPDVEEEDEPPKIHAAPKNKKRKEIGGQNNDKEAEWGDAMKECSCSCHEGSGELKLKKSKRRSCSHCSSKVCENKFYKNKDSQELSASLVQQESSPQPEGKDSGTSKEPAEENLENRDEGEDVQSRTRTVSRKGEPLPAGSQPEGRAVCSRHTSPDKAALPERRVQEGGVSAAKDSPFVAVPGWTRLQKAAPKLPQETKGSPCSAGSGSEGLKQQHQGDVDASLELSRDLLLSSRSATVKGSMRPGSSKNSLCQTEGLPSDSSDKFGHSSKLSAREFEGSPLPLEGKSEAKQSWITPARKPALGKSCCSPSPSNCALEADSMGCTGSVPENRLKSNANNCFQVHRHSEELEYRVCTASLGQKEEEQQQQRVTEATVCAKNSKVSSTGEKVVLWTREADRVILTTCQEKGAHLETFQAISQKLGNKTAAEVSHRFRELMKLFHTSCDGSSEDEEDATSTSNADQLSDKDLLLSEEEPDD", "length": 2215, "header": "tr|A0A8V1ADR8-1|A0A8V1ADR8_CHICK Isoform 1 of GON-4-like protein OS=Gallus gallus OX=9031 GN=GON4L PE=4 SV=1 CANONICAL=A0A8V1ADR8-1" }, "locus": { "chromosome": "25", "start_pos": 2200364, "end_pos": 2180892, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068875.1", "url": "https://www.ensembl.org/id/ENSGALT00010068875.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042317.1", "url": "https://www.ensembl.org/id/ENSGALP00010042317.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0AAA9TS91-1", "protein_name": "GON-4-like protein", "gene_name": "GON4L", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MLPCKKRRTTLTESPQHQGNQEEDDLDLQAAGKPESDLGSVKDLGSVSLSWSPSHGRAADLEVQAAGIQLGMEDPSLSSRMLTEDTNVAVLEAVDVAISQEITLASLESSQPVNTHIGKGKLQATSSRRGKKITLRPGSVTQEDRGDHPIAKEPFSEEPSEEVKAEGGKSQMHSGGEMPSLPSDSHSAKPAAPPRKSSQPDVCASPQEKPLRTLAHQAEEETEDGGLFIPMEEHDGEENEKRRKKKKGTKRKRDGRDQEERTLSCDLKLDDMLDRTLEDGAKQHNLTAVNVRNILHEVITNEHVVAMMKAAISETEDMPMFEPKMTRSKLKEVVEKGVVIPTWNISPIKKANEIKPPQFVDIHLEDDDSSDEEYQPDDEEEDETAEESLLESDVESTASSPRGAKKSRLRQSSEMTETDEESGILSEAEKVTTPAIRHISAEVVPMGPPPPPKPKQTRDSTFMEKLHAVDEELASSPVCMDSFQPMDDSLIAFRTRSKMPLKDVPLGQLEAELRAPDITPDMYDPNTADDEDWKMWLGGLMNDDVGNEDEADDDDDPEYNFLEDLDEPDTEDFRTDRAVRITKKEVNELMEELFETFQDEMGFSNMEDDGPEEEERVAEPRPNFNTPQALRFEEPLANLLNEQHRTVKELLEQLKMKKSSAKQQQEVERVKPQREKVHQTLILDPAQRKRLQQQMQQHVQLLTQIHLLASSNPSLSSEASTTRIFLKELGTFAQSSIALHHQFNSKFQTLFQPCNLMGAMKLIEDFSTHVSVDWSPRKTVKKTACKLPCLPKQVAWILATSKVFMYPELLPVCSLKAKNPQDKIFFTKAEDNLLALGLKHFEGTEFPKPLISKYLLTCKTAHQLTVRIKNLNMNRAPDNIIKFYKKTKQLPILMKCCEEIQPHQWKPPVEREEHRLPFWLKASLPSIQEELRRIADGAREVGNVTGTTEINSDPGLGKGSSELESETRYPLLLPKGVVLKLKPVANRFSRKAWRQKRSSTLKPFFFGPSPSLQPSSSSGKTPARSAHSEAPPSKMVVRIPPLIQPATVLQAVPGGPPLGVPGGDSFESPAALPATAAEARTSFPLPEPQTLLSSAPVPKLMLPSLAPSKFRKPCVKRRASKRKGPKASLCLKPAPLIHPAPVFFTVPATTVKVVSLGSGCNVMQPVSAAVAQSPQTIPITTLLVNPTPFPCSLNQPLVASSIPPLIVSGTSVNLSVPSTPEDKAPVNVDVGCPLAEGKNAFQGLEPKLEPRELSPLCAAVFPKEEHSPGPPAADRVCQEQLSESSAYGWTIVKTEEGRQAPEPLPQGFRESLNPPEDLEEMVKMEPKDPGEDTCGGSLEQGSHEEIKEEHSVESDTSFPSEESSRPREGKKQTGLQQEEQRSQAAQTLSASQEPPGEGNSGDVSKGSPRDASFSTDPEMVLSSPLGKPEDLSSVDGQSVGTPAGPETAGEKDGPEEEEEEDFDDLTQDEEDEMSSASEESVLSVPELQETMEKLTWLASERRMSQEGESEEENSQEENSEPEEEEEEEAEGMENLQKEDEMMDEAIGDPAEKPPATFDSPKAAPEVETSRTPPGESIKAAGKGRSNHRARSKRGSRARASKDTSKLLLLYDEDILERDPLREQKDLAFAQAYLTRVREALQHIPGKYEDFLQVIYEFESSTQRQTAVDLYKSLQILLQDWPQLLKDFAAFLLPEQALACGLFEEQQAFEKSRKFLRQLEICFAENPSHHQKIIKVLQSCADCLPQEITELKTQMWQLLKGHDHLQDEFSIFFDHLRPAASRMGDFEEINWTEEKEYEFDGFEEVALPDVEEEEEPPKIPTTSKNKRRKEIGVQNHDKEAEWPDAAKDCACSCHEGGPDSKMKKSKRRSCSHCSSKVCDSKSYKSKEPHELVGSSPHREASLMPGAKEAGQGKDVMEEEAPEERESVEAAQSRTGRSTRKGEMPAAAGLAAGSTLPSPQEVTFTDQLLLDGPPPPCSPETPQLPSTAGTVLCAVRSNQAGPAVLSGPRASPRPQHEGEDHKPGAELEPSMPWDASETEKLPGTVEPPASFLSPVSSRTGDFGRRQVPGRADTQESWLPSGRAGVSTADGMSPLRGVSSAGVDTAETSKAPRGGLAKDSGAQGKGPAGELQAKATEATVCANNSKVSSTGEKVVLWTREADRVILTMCQEQGAQPQTFSVISQQLGNKTPTEVSHRFRELVQLFHTACEASSEDEDDATSTSNTDQLSDHGDLLSEEELDE", "length": 2239 }, "evidence": [ { "id": "A0A8V1ADR8", "url": "https://omabrowser.org/oma/group/A0A8V1ADR8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1QI87-1", "protein_name": "GON-4-like protein", "gene_name": "gon4lb", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGWKRKSSSPEPQPNLVKLPKRESLSRSPSSWKRKASTPSKTKSWTSIQSLSPDRHVDQCNGQEKMSSAGHVEDDSDCIQSSTPVSSPLRSEEDAELGLVITVDEDRCEGEEWLKKRNGVNIKKNGINQTEGEIPQKEDGDVEKTMEQLSEEDENEEELRKLDRDLTLKSKKLNLSSINVRNIIHEVVTNEHVVAMMKAAIKETQDMPMFEPKMTRSKLKEAVEKGVGMGNWNISPIKKANDIKPPQFVDIPLQEEEDSSDEEYCPDEDEEDETAEETFLESDVESTSSSPRGIRRFPSQTPPHCDDASNSPRLKPRLARHLRVEAVPMGPPAPPPQSCGLSRSLKTLDPFIEKLHAVDKELELSPLCMEPYQALSSGGAGEPDDSLVACRTRSKRPLRDVPLDQLEAELRAPDITPDMYDNVSTPEDREWTQWLQGLMTSHLDNDEEADEDDDPEYNFLDDLDEPDLEDYRNDRAVRITKKEVNELMEELFETFHDELAANEPDDEGHDEDEEREEEANDTPQFNVPQAIRFEEPLAHMLTACRRTVREQLDALQQRRENQVRTTQHASGPGMVFVQPSCPLVVTPAQRIQLQQQIQQHVQLLTQVSMLCDPVGALQTEAQTTKHFLGELLSFAERAEEERSAVNLGFKSVFRVCNLLSSINLLEEVKQSPSLSCLPPKPNRHHSVHSYPLLPAGLAWLFATRSVFLYPELLPHCSLDPALHPSRSKHYYSKGEDGLLVLGLKHFAQTEFPYQLISRYLIRPKRQEQLRMRVKDMVSPKYPHNIIKYYCQNHVVPPLPVVCKPVVHGEERPPVEREQEVMPNWLKKSLPLIQKSICQSDLTMTSTTKSASLPFPKETRYPQFLPKGLSLRLHPSQVASRPSQPKSRILRAFTNRTLAPLAKAPSCPTGTGHLLTNISTPVLLLAQAPSTPINGVFPLVHPSLTPAHGTVPLNASYPINFHYLSPELGASNPAHLPANLPPSVVQKPQCDVPLLSTGTVKTHGVQQQTSDKHKKRTMPRKLAPLRPAPQLPRLLPLSSGSIGNISNPGIIIDQQISLNVPHNLQSDNVIVIKAHENVNTHRTVPSLSPDLVVQLVPQTQVAENTTSSLPRKTTPRSDVSQTAKDIPSVQSSGENGQRTVFSPQTAAPAAVDSSQFVLVQTVSPTGPPQFLLLPQDSLVLNQPASLPSEGTLQNLSQQTSHLDISTTSTALKNSEKTEVHLNNPTTSLPVSREEDGERQEVDEEMVGDRWEEEMASALFGSPLLALSESSCSPDSSPDASMDSGSDAMVRVEMEDGELPSVHSASATQETPDVHKHSSGDEKEQQSSGGEKQNSGNEEGRAEESESRKDEAQDEDKGGEKNEDGEGDGKRDEGGSGDKGREEKDGDGEKDGDGERDEEEEDFDDLTQDEDEEEVMSSASEESVLSVPELQETMEKLTWLASERRLCREGDSEEDNSPTSPTSPTSPNSQNSPASQNSQEENSEDEDDGAMKGDELEAGEGEGEKLPEGDAPAGDDPPQISEKVGGRGRGRGRPPPRSLKRGRRQERGSKDASKLLLLYDDHILDNDPMRESKDMAYAQAYLNRVREALQDVPGKVEEFLGLLYEFDQAGESHSVIELFAQLKQLLKDWPELLKDFAAFLLPEQALECGLFEEQQAFERSRRFLRQLEISFGENPSHYQKIVRALQSGSPLSPAGIEELKTQMATLLKGHTHLQGEFWMFFDEMRPPPARPGQFEEAVWPEDVATGTDGEAGVSVTSRGGVWGGFEEVTLPDLDEDEESHKIRQISSRSKRRKELHTYKDCDWPEKDCSCSCHDSVHDAKHRRHKRKGCLRCQSNKAANGSKVLKGRDSAFSSADAQSERGGEEKEEERVLGEDGEAEKELKDETGSGANSPHHDGEGSVWEREERATSSIPEEQNTHNQDDEEKTEEKNHHASPEKHSRDEEDSAESGQTEAAQQSSLSPALDAPVCAKNISLTPTGERVILWTREADRVILTTCQQQGASQSTFQAVSEQLGNKTASEVSRRFRDLMRLFHTSASQASSEDEAAEQQSATDEEQD", "length": 2055 }, "evidence": [ { "id": "A0A8V1ADR8", "url": "https://omabrowser.org/oma/group/A0A8V1ADR8/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q3T8J9-1", "protein_name": "GON-4-like protein", "gene_name": "GON4L", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLPCKKRRTTVTESLQHKGNQEENNVDLESAVKPESDQVKDLSSVSLSWDPSHGRVAGFEVQSLQDAGNQLGMEDTSLSSGMLTQNTNVPILEGVDVAISQGITLPSLESFHPLNIHIGKGKLHATGSKRGKKMTLRPGPVTQEDRCDHLTLKEPFSGEPSEEVKEEGGKPQMNSEGEIPSLPSGSQSAKPVSQPRKSTQPDVCASPQEKPLRTLFHQPEEEIEDGGLFIPMEEQDNEESEKRRKKKKGTKRKRDGRGQEGTLAYDLKLDDMLDRTLEDGAKQHNLTAVNVRNILHEVITNEHVVAMMKAAISETEDMPMFEPKMTRSKLKEVVEKGVVIPTWNISPIKKANEIKPPQFVDIHLEEDDSSDEEYQPDDEEEDETAEESLLESDVESTASSPRGAKKSRLRQSSEMTETDEESGILSEAEKVTTPAIRHISAEVVPMGPPPPPKPKQTRDSTFMEKLHAVDEELASSPVCMDSFQPMDDSLIAFRTRSKMPLKDVPLGQLEAELQAPDITPDMYDPNTADDEDWKMWLGGLMNDDVGNEDEADDDDDPEYNFLEDLDEPDTEDFRTDRAVRITKKEVNELMEELFETFQDEMGFSNMEDDGPEEEECVAEPRPNFNTPQALRFEEPLANLLNEQHRTVKELFEQLKMKKSSAKQLQEVEKVKPQSEKVHQTLILDPAQRKRLQQQMQQHVQLLTQIHLLATCNPNLNPEATTTRIFLKELGTFAQSSIALHHQYNPKFQTLFQPCNLMGAMQLIEDFSTHVSIDCSPHKTVKKTANEFPCLPKQVAWILATSKVFMYPELLPVCSLKAKNPQDKIVFTKAEDNLLALGLKHFEGTEFPNPLISKYLLTCKTAHQLTVRIKNLNMNRAPDNIIKFYKKTKQLPVLGKCCEEIQPHQWKPPIEREEHRLPFWLKASLPSIQEELRHMADGAREVGNMTGTTEINSDRSLEKDNLELGSESRYPLLLPKGVVLKLKPVATRFPRKAWRQKRSSVLKPLLIQPSPSLQPSFNPGKTPARSTHSEAPPSKMVLRIPHPIQPATVLQTVPGVPPLGVSGGESFESPAALPAVPPEARTSFPLSESQTLLSSAPVPKVMLPSLAPSKFRKPYVRRRPSKRRGVKASPCMKPAPVIHHPASVIFTVPATTVKIVSLGGGCNMIQPVNAAVAQSPQTIPITTLLVNPTSFPCPLNQSLVASSVSPLIVSGNSVNLPIPSTPEDKAHVNVDIACAVADGENAFQGLEPKLEPQELSPLSATVFPKVEHSPGPPLADAECQEGLSENSACRWTVVKTEEGRQALEPLPQGIQESLNNPTPGDLEEIVKMEPEEAREEISGSPERDICDDIKVEHAVELDTGAPSEELSSAGEVTKQTVLQKEEERSQPTKTPSSSQEPPDEGTSGTDVNKGSSKNALSSMDPEVRLSSPPGKPEDSSSVDGQSVGTPVGPETGGEKNGPEEEEEEDFDDLTQDEEDEMSSASEESVLSVPELQETMEKLTWLASERRMSQEGESEEENSQEENSEPEEEEEEEAEGMESLQKEDEMTDEAVGDSAEKPPTFASPETAPEVETSRTPPGESIKAAGKGRNNHRARNKRGSRARASKDTSKLLLLYDEDILERDPLREQKDLAFAQAYLTRVREALQHIPGKYEDFLQVIYEFESSTQRRTAVDLYKSLQILLQDWPQLLKDFAAFLLPEQALACGLFEEQQAFEKSRKFLRQLEICFAENPSHHQKIIKVLQGCADCLPQEITELKTQMWQLLKGHDHLQDEFSIFFDHLRPAASRMGDFEEINWTEEKEYEFDGFEEVALPDVEEEEEPPKIPTASKNKRKKEIGVQNHDKETEWPDGAKDCACSCHEGGPDSKLKKSKRRSCSHCSSKVCDSKSYKSKEPHELVGSSPHREASPMPGAKEAGQGKDMMEEEAPEERESTEATQSRTVRTTRKGEMPVSAGLAVGSTLPSPREVTVTERLLLDGPPPHSPETPQFPPTTGAVLYTVKRNQVGPEVRSCPKASPRLQKEREGQKAVSESEALMLVWDASETEKLPGTVEPPASFLSPVSSKTRDAGRRHVSGKPDTQERWLPSSRARVKTRDRTCPVHESPSGIDTSETSPKAPRGGLAKDSGTQAKGPEGEQQPKAAEATVCANNSKVSSTGEKVVLWTREADRVILTMCQEQGAQPQTFNIISQQLGNKTPAEVSHRFRELMQLFHTACEASSEDEDDATSTSNADQLSDHGDLLSEEELDE", "length": 2241 }, "evidence": [ { "id": "A0A8V1ADR8", "url": "https://omabrowser.org/oma/group/A0A8V1ADR8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q535K8-1", "protein_name": "GON-4-like protein", "gene_name": "Gon4l", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLPCKKRSGVTESAQQQDDQEGEDLHLEAAVKPDTDQLPDCTSESLSWGQSHDSAGCPEVHSMQDVGSQLSVEGTPLSSKMLTQRVNLAVSEAVDVPVSQEIPVPSLESSHSLPVHMGKGRLQSTASRKGKKIAFMPGQVTREDGGDHTVPEEPPSGEHAEEVKAEGGELEMHSEGDLPSLSSGSQSAKPRAQPRKSFQPDGSAFPQEKSLGPLVRQAEEDMEDGGLFIPTEEQDGEESDKRKKTKKGTKRKRDGRGQEQGTMTYDPKVDDMLDRTLEDGAKQHNLTAVNVRNILHEVITNEHVVAMMKAAISETEDMPLFEPKMTRSKLKEVVEKGVVIPTWNISPIKKASETKQPPQFVDIHLEDDDSSDEEYQPDEEEEDETAEESLLESDVESAASSPRGVKRSRLRLSSEAAEADEESGVLSEVEKVATPALRHISAEVVPMGPPPPPKPKQTRDSTFMEKLNAVDEELAASPVCMDSFQPMEDSLIAFRTRSKMPLKDVPLGQLEAELQAPDITPDMYDPNTADDEDWKLWLGGLLNDDVENEDEADDDDDPEYNFLEDLDEPDTEDFRTDRAVRITKKEVNGLMEELFETVQSVVPSKFQDEMGFSNMEDDGPEEEERVTESRPSFNTPQALRFEEPLANLLNERHRTVKELLEQLKMKKSSVRQQPEVEKLKPQTEKVHQTLVLDPAQRSRLQQQMQQHVQLLTQIYLLTTSNPNLSSEASTTRVFLKELGTFAENSTALHQQFNPRFQTLFQPCNWVGAMQLIEDFTHISIDCSPHKTVKKTASEFPCLPKQVAWILATNKVFMYPELLPICSLKANNPRDKTIFTKAEDNLLALGLKHFEGTEFPKPLISKYLVTCKTAHQLTVRIKNLNLNRAPNNVIKFYKKTKQLPVLVRCCEEIQPHQWKPPIEKEEHRLPFWLKASLQSIQEELRNLAGGATAGGSVTAATETSTDQHLQKTSPVVGGDTQYPLLLPKGVVLKLKPGSKRFSRKAWRQKRPLVQKPLLIQPSPSVQPVFNPGKMATWPTQSEVPPSNTVVQIPHLIQPAAVLQTLPGFPSVGVCGEDSFESPAALPAMPSGSEARTSFPWSESQSAPPSSSAPKLMLPSLGPSKFRKPYVRRKPTRRKGAKASPCVKPAPIIHPTPVIFTVPATTVKVVSLGGGCNMIQPVTAAVAPSPQTIPITTLLVNPTSFPCSLNQPLVASSISPLLVSSNPLALPVTSLPEEKAHVSLDIAEGKNAPQNPEPKIKPQEPTPQCATVFSKEEPRSWHPSADTGNQEAVSESSACSWAAVKTEGQEGSSEKSVCGWTVVKTEDGGHAVQPLPQDPQDSLNSPSKDLLNMVKLEAEDCMEEISSDFPKQDIGEEVKEECCMELDRDSPQEKASSVSEMSKQTATPREETQAAKSPTVSQDAPDAIRDASKGLPQSTLSSMDQGTVLNSPPGKPEDSANADGQSVGTPAGTDTGAEKDGAEEEEEEDFDDLTQDEEDELSSASEESVLSVPELQETMEKLTWLASERRMSQEGESEEENSQEENSEPEEEEEEEAEGMETLQKEDEATDEAGGGAAEKPPSTLASPHTAPEVETSITPAGESIKAAGKGRSSHRARSRRGSRARASKDASKLLLLYDEDILDRDPLREQKDLAFAQAYLTRVREALQHIPGKYEDFLQIIYEFESNAQMHSAVDLFKSLQTLLHDWPQLLKDFAAFLLPEQALSCGLFEEQQAFEKSRKFLRQLEICFAENPSHHQKIIKVLQGCADCLPQDITELKTQMWQLLRGHDHLQDEFSIFFDHLRPAANRMGDFEEINWTEEKEYEFDGFEEVILPEVEEEEEPAKVSTASKSKRRKEIGVQHQDKESEWPEAAKDGSCPCHEGGPESKLKKSKRRNCHCSSKVCDSKSYKSKEPLELVGSGPLQEASTVPGTKEAGQGKDMSEEETMEGQENVEVSQNKTGRTTRKGEAPIPGSTVRTALLCSAEVTPIELSLEGPTCCSPETPRLPPQTGAVVCSVRRNQAGPEVVSCLGTSSIPPKEGEDQKAVANSETIAPLPETSETERLPGTVELPAPLPSPVSLSTRDTGRRHIYGKAGTQSWLLDNRAEAKAAHMVAPIRGTSSGASASEAAPTASREGLAEDSETQGKGPEAVLPKASEATVCANNSKVSSTGEKVVLWTREADRVILTMCQEQGAQPHTFSVISQQLGNKTPVEVSHRFRELMQLFHTACEASSEDEDDATSTSNADQLSDHGDLLSEEELDE", "length": 2256 }, "evidence": [ { "id": "A0A8V1ADR8", "url": "https://omabrowser.org/oma/group/A0A8V1ADR8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADR8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADR8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADR8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADR8" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADR8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADR8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "transcription corepressor activity", "id": "GO:0003714", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003714", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADR8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADR8" } ], "pmid": "" }, { "name": "transcription coregulator activity", "id": "GO:0003712", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003712", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADR8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADR8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1204, "end_pos": 1206, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1205, "end_pos": 1207, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1212, "end_pos": 1214, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1227, "end_pos": 1229, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1347, "end_pos": 1349, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1721, "end_pos": 1723, "annotation": "n_glycosylation_sequon" }, { "start_pos": 213, "end_pos": 215, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2161, "end_pos": 2163, "annotation": "n_glycosylation_sequon" }, { "start_pos": 272, "end_pos": 274, "annotation": "n_glycosylation_sequon" }, { "start_pos": 539, "end_pos": 541, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1204, "end_pos": 1206 }, { "start_pos": 1205, "end_pos": 1207 }, { "start_pos": 1212, "end_pos": 1214 }, { "start_pos": 1227, "end_pos": 1229 }, { "start_pos": 1347, "end_pos": 1349 }, { "start_pos": 1721, "end_pos": 1723 }, { "start_pos": 213, "end_pos": 215 }, { "start_pos": 2161, "end_pos": 2163 }, { "start_pos": 272, "end_pos": 274 }, { "start_pos": 539, "end_pos": 541 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1ADS8-1", "uniprot_ac": "A0A8V1ADS8", "uniprot_id": "A0A8V1ADS8_CHICK", "mass": { "chemical_mass": 57487.0, "monoisotopic_mass": 57487.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "One cut homeobox 3", "type": "synonym", "evidence": [ { "id": "A0A8V1ADS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADS8/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADS8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADS8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADS8", "locus": {} } ], "crossref": [ { "id": "A0A8V1ADS8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1ADS8", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR003350", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003350", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010982", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010982", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051649", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051649", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR14057", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14057", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14057:SF34", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14057:SF34", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02376", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02376", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1ADS8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADS8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ADS8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADS8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MELAMENLGSLHGVPHSQPAELLSPAHGRQSSHRNLVPHGRPAMVSGMASILEGGDYRAEHSLAAPLHPAMSMSCESPSGMSLSSTYTTLTPLQHLPPISTVSEKFHHPHHHHHHHHHPHQRLAGNVSGSFTLMRDERSLASMGNLYSHYPKDMPAMGQPLSPLPNGLGSLHNAQQPLTPYGPGGHLPNDKMLSPNGFDSHAAMLSRGEEHLARGLGAPSSAMMPPLNGMHPHGHPHPQAGGSLLAERDRQASASGSQSGGSGQVEEINTKEVAQRITAELKRYSIPQAIFAQRILCRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAEPKGFPEIERVKKKKKKEEEEELITTRISSGLNSFPFCENKTKQKKKYRSGAPCDGFNSAQLRQSRPDRAVPHRAAPPTIRTRPPHLPGPGGPPHIAPRFVPNLRPLCRPDGRRFRFASSAWVGSGQPQKRSGRADGGQGPPGTRGWGATVGREGPHGRPRPRSPDGAAAPRPLRLRQTRL", "length": 525, "header": "tr|A0A8V1ADS8-1|A0A8V1ADS8_CHICK Isoform 1 of One cut homeobox 3 OS=Gallus gallus OX=9031 GN= PE=3 SV=1 CANONICAL=A0A8V1ADS8-1" }, "isoforms": [ { "isoform_ac": "A0A8V1ADS8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADS8/entry#A0A8V1ADS8-1", "sequence": { "sequence": "MELAMENLGSLHGVPHSQPAELLSPAHGRQSSHRNLVPHGRPAMVSGMASILEGGDYRAEHSLAAPLHPAMSMSCESPSGMSLSSTYTTLTPLQHLPPISTVSEKFHHPHHHHHHHHHPHQRLAGNVSGSFTLMRDERSLASMGNLYSHYPKDMPAMGQPLSPLPNGLGSLHNAQQPLTPYGPGGHLPNDKMLSPNGFDSHAAMLSRGEEHLARGLGAPSSAMMPPLNGMHPHGHPHPQAGGSLLAERDRQASASGSQSGGSGQVEEINTKEVAQRITAELKRYSIPQAIFAQRILCRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAEPKGFPEIERVKKKKKKEEEEELITTRISSGLNSFPFCENKTKQKKKYRSGAPCDGFNSAQLRQSRPDRAVPHRAAPPTIRTRPPHLPGPGGPPHIAPRFVPNLRPLCRPDGRRFRFASSAWVGSGQPQKRSGRADGGQGPPGTRGWGATVGREGPHGRPRPRSPDGAAAPRPLRLRQTRL", "length": 525, "header": "tr|A0A8V1ADS8-1|A0A8V1ADS8_CHICK Isoform 1 of One cut homeobox 3 OS=Gallus gallus OX=9031 GN= PE=3 SV=1 CANONICAL=A0A8V1ADS8-1" }, "locus": { "chromosome": "28", "start_pos": 2737137, "end_pos": 2733756, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068885.1", "url": "https://www.ensembl.org/id/ENSGALT00010068885.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042327.1", "url": "https://www.ensembl.org/id/ENSGALP00010042327.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADS8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADS8" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADS8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADS8" } ], "pmid": "" }, { "name": "transcription regulator complex", "id": "GO:0005667", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005667", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADS8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADS8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADS8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADS8" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADS8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADS8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADS8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADS8" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADS8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADS8" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADS8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADS8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 126, "end_pos": 128, "annotation": "n_glycosylation_sequon" }, { "start_pos": 384, "end_pos": 386, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1ADS8", "database": "UniProtKB", "url": 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protein 221", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015155607" }, "gene_names": [ { "name": "TMEM221", "type": "recommended", "evidence": [ { "id": "A0A8V1ADT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADT3" } ] }, { "name": "TMEM221", "type": "synonym", "evidence": [ { "id": "XP_015155607", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015155607" } ] } ], "protein_names": [ { "name": "Transmembrane protein 221", "type": "synonym", "evidence": [ { "id": "A0A8V1ADT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADT3/entry#names_and_taxonomy" } ] }, { "name": "transmembrane protein 221", "type": "synonym", "evidence": [ { "id": "XP_015155607", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015155607" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052559.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015155607.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015155607", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015155607" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADT3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADT3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TMEM221", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADT3", "locus": {} } ], "crossref": [ { "id": "A0A8V1ADT3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1ADT3", "database": "AlphaFoldDB", "categories": [] }, { "id": "100858428", "url": "https://www.ncbi.nlm.nih.gov/gene/100858428", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR029201", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029201", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR053101", "url": "https://www.ebi.ac.uk/interpro/entry/IPR053101", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:100858428", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100858428", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CPRMHRT", "url": "https://omabrowser.org/oma/group/CPRMHRT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ADT3", "url": "https://www.orthodb.org/?gene=A0A8V1ADT3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR36132", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR36132", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR36132:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR36132:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15038", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15038", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015155607", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015155607", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1ADT3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADT3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ADT3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADT3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPSYPQRTLTVLLLFGTLSAAMALLASSLIFQLPAGRTSPGSGPGAVRGALPESAAAVLLPVSAVLAALCLVLNVSCLLLCLLHGYFSTELCRGQPGPERADWFLLDSRTVRHAAIGLFCCGVSVYLTALAIYMLLLFELEAGIASACILSSGIIVLLVTVTHALLRASQLSRRSRSEISHTLYENDSAQHSETPGSNLNNKSTAVPRPRPEIHREFSFPPFLEHKSQLGSPASSNLTSSGSPGAHSEKESYHLPRTHRTLSAESALLQAQGKPWNGVTHEMRNVLARKPGASGKDSTLV", "length": 300, "header": "tr|A0A8V1ADT3-1|A0A8V1ADT3_CHICK Isoform 1 of Transmembrane protein 221 OS=Gallus gallus OX=9031 GN=TMEM221 PE=4 SV=1 CANONICAL=A0A8V1ADT3-1" }, "isoforms": [ { "isoform_ac": "A0A8V1ADT3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADT3/entry#A0A8V1ADT3-1", "sequence": { "sequence": "MPSYPQRTLTVLLLFGTLSAAMALLASSLIFQLPAGRTSPGSGPGAVRGALPESAAAVLLPVSAVLAALCLVLNVSCLLLCLLHGYFSTELCRGQPGPERADWFLLDSRTVRHAAIGLFCCGVSVYLTALAIYMLLLFELEAGIASACILSSGIIVLLVTVTHALLRASQLSRRSRSEISHTLYENDSAQHSETPGSNLNNKSTAVPRPRPEIHREFSFPPFLEHKSQLGSPASSNLTSSGSPGAHSEKESYHLPRTHRTLSAESALLQAQGKPWNGVTHEMRNVLARKPGASGKDSTLV", "length": 300, "header": "tr|A0A8V1ADT3-1|A0A8V1ADT3_CHICK Isoform 1 of Transmembrane protein 221 OS=Gallus gallus OX=9031 GN=TMEM221 PE=4 SV=1 CANONICAL=A0A8V1ADT3-1" }, "locus": { "chromosome": "28", "start_pos": 4030545, "end_pos": 4026899, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068890.1", "url": "https://www.ensembl.org/id/ENSGALT00010068890.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042332.1", "url": 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"MARSYGGRVLAAMVLLGIPAAVLAALGAQLLFQLQAGRAELRGPRIDGLGPELGAGPRLPEDAAGALLPLAAALSALALVLGLTCLLLAALCGHLGAEMARGPGSNRSDWFLYDCRLLRHVALGLFCCGVSVYLAALSIYALLLFEIETGAAAASILGLGALVLVAALTHTLLQAARTTRRGVHELSPPHFEDDPVCPAEVSKAGPRAQPQQGTHHWTLYSSFPKLGDSLRPMVTDTAPAVMGGGRESCLPASRMHRTLSASEGRWGEVTHEMRSILGHRPAGSGKDSTLV", "length": 291 }, "evidence": [ { "id": "A0A8V1ADT3", "url": "https://omabrowser.org/oma/group/A0A8V1ADT3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "E7EXZ1-1", "protein_name": "Transmembrane protein 221", "gene_name": "tmem221", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTHSYSQRSLVILAFLGILSSIMAVLSVILIFQLQTQQAVIKDSPTFVPKDITAVLLPVSTVLSALSLTLNLSSVVVCLLHSYFATEICRGEPDTQRADWFLMDSRAVRHVTIGLFCLGVSVYLAAMSIYMVLVFEVETGIASVCVLSSGVLVLLLIIIHSLIRAARAAKHYRTDHLHTMYHNNPEQIRTSNLSIMENPRRQHSLANLPSHFINPAHMEPKSQYSTSNGPQAHSSDKDGCSGSGRTHRTLSTESGLFHAQAKPWNGVNSEMRSVLARKATIKDSTLV", "length": 287 }, "evidence": [ { "id": "A0A8V1ADT3", "url": "https://omabrowser.org/oma/group/A0A8V1ADT3/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 186, "end_pos": 188, "annotation": "n_glycosylation_sequon" }, { "start_pos": 201, "end_pos": 203, "annotation": "n_glycosylation_sequon" }, { "start_pos": 236, "end_pos": 238, "annotation": "n_glycosylation_sequon" }, { "start_pos": 74, "end_pos": 76, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], 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On Dec 3, 2021 this sequence version replaced NP_001366269.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001366269", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001366269" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADU3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADU3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "EFCAB12", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADU3", "locus": { "chromosome": "25", "start_pos": 2238007, "end_pos": 2229953, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028449", "url": "https://www.ensembl.org/id/ENSGALG00010028449" } ] } } ], "crossref": [ { "id": "A0A8V1ADU3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1ADU3", "database": "AlphaFoldDB", "categories": [] }, { "id": "770278", "url": "https://www.ncbi.nlm.nih.gov/gene/770278", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR028034", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028034", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040673", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040673", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042847", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042847", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "RVIAHCF", "url": "https://omabrowser.org/oma/group/RVIAHCF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ADU3", "url": "https://www.orthodb.org/?gene=A0A8V1ADU3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47225", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47225", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47225:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47225:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14908", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14908", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18289", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18289", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001366269", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001366269", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1ADU3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADU3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ADU3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADU3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVGLLELIANIERWSKTDGCSTVTFPTLEQLSINDVTTIWNNMFQRVHQLLLLKKPPAVSITGLGTFCIQKWQALEDGKTLTFQRPLFSLSEAVAQIRDFRHPSIHLPDDTEMVVLNCETIRLHTPYSQQTVQGCLLETLQYFYHILTNGEDADFTLKDIGTLAIRGEHMEMTFCEDFLLRLNKSTYVVQKLFNKRWVVLDKETAHLPSHFGHVHLLPKFEIKEVPQLATKPLPKEKLLERKGSLLCKLLRLRRTISLSTLTTVEINDEEEPAGRPLPQTPDTEGRQEEESPSFPVVTCHPEDDPHNLSAWIQERKQFISQLESFGDVEKWLSNKSSKSHLEERVWERIKSRRAARRAEGKSAMTDNLGDTTSASSQPQKDVAPPCIPYPQALVTLHDLLRRRKTTLVNVFKKAGMEGRNIKKADFIKIIKQTNVPIGEKDLDDVIIFLAAPNRGKYITMEKLMECQNEWLEMKKKESKETKAGAQTQPPKAACKTATSPPSAGGRAKGMDPTKPQVKLTPLEDTPVQAEPGQGHQTDHEKKDTPEPSGDRTQKTIKRQEIKKDKGSPIKWKEMSQLGRSGEVTVEEHCFPSTTGSDTGVLIDQYRRKVAASYLNSSKLCKEHDIHLTEPVLQKGLLHPGDKIIRGRRLRKIRQPGGYYNIGLADMSSPLSMSGSSKSAAGNLGKEGKNKRTSEESGHYDSRQRNRKEMEGSDNKFWPGHLLDKMRLCIPEEKINRAHPLFSCVHPTRPAYHII", "length": 754, "header": "tr|A0A8V1ADU3-1|A0A8V1ADU3_CHICK Isoform 1 of EF-hand calcium binding domain 12 OS=Gallus gallus OX=9031 GN=EFCAB12 PE=4 SV=1 CANONICAL=A0A8V1ADU3-1" }, "isoforms": [ { "isoform_ac": "A0A8V1ADU3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADU3/entry#A0A8V1ADU3-1", "sequence": { "sequence": "MVGLLELIANIERWSKTDGCSTVTFPTLEQLSINDVTTIWNNMFQRVHQLLLLKKPPAVSITGLGTFCIQKWQALEDGKTLTFQRPLFSLSEAVAQIRDFRHPSIHLPDDTEMVVLNCETIRLHTPYSQQTVQGCLLETLQYFYHILTNGEDADFTLKDIGTLAIRGEHMEMTFCEDFLLRLNKSTYVVQKLFNKRWVVLDKETAHLPSHFGHVHLLPKFEIKEVPQLATKPLPKEKLLERKGSLLCKLLRLRRTISLSTLTTVEINDEEEPAGRPLPQTPDTEGRQEEESPSFPVVTCHPEDDPHNLSAWIQERKQFISQLESFGDVEKWLSNKSSKSHLEERVWERIKSRRAARRAEGKSAMTDNLGDTTSASSQPQKDVAPPCIPYPQALVTLHDLLRRRKTTLVNVFKKAGMEGRNIKKADFIKIIKQTNVPIGEKDLDDVIIFLAAPNRGKYITMEKLMECQNEWLEMKKKESKETKAGAQTQPPKAACKTATSPPSAGGRAKGMDPTKPQVKLTPLEDTPVQAEPGQGHQTDHEKKDTPEPSGDRTQKTIKRQEIKKDKGSPIKWKEMSQLGRSGEVTVEEHCFPSTTGSDTGVLIDQYRRKVAASYLNSSKLCKEHDIHLTEPVLQKGLLHPGDKIIRGRRLRKIRQPGGYYNIGLADMSSPLSMSGSSKSAAGNLGKEGKNKRTSEESGHYDSRQRNRKEMEGSDNKFWPGHLLDKMRLCIPEEKINRAHPLFSCVHPTRPAYHII", "length": 754, "header": "tr|A0A8V1ADU3-1|A0A8V1ADU3_CHICK Isoform 1 of EF-hand calcium binding domain 12 OS=Gallus gallus OX=9031 GN=EFCAB12 PE=4 SV=1 CANONICAL=A0A8V1ADU3-1" }, "locus": { "chromosome": "25", "start_pos": 2237355, "end_pos": 2230785, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068902.1", "url": "https://www.ensembl.org/id/ENSGALT00010068902.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042344.1", "url": "https://www.ensembl.org/id/ENSGALP00010042344.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "F1M1Q8-1", "protein_name": "EF-hand calcium binding domain 12", "gene_name": "Efcab12", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSPILKKRPREETVSCLSPNKFLAKSCNLRGGGHKQTRRPGDQKTHALGKAPPHPSDAPKWNAGTPGHPSSAPSQNSAETLAKYSWKQKKASRLWEFQKAEEKKKSRVTFSLSVTDLGAHQSFTSIDDDFDDAASKAPVFKPELVTAHCFRRLKQKDFRLPQSRRRIIIVSGTKDQVPAQPTTPPQAPLPLTPSFKVPDTGDTQELPVNMKLWLSQRAKLRKQLETFGDVKTWLDNKPTITSSEFKVLCMIRREQTAPKRTLISVGKPKGKPLKYIRQPIPQLRLPKPPVLSDMYAFLRSRKIKIQEVFSKADRGENHRISREEFLMAVKAIGVPLKTQELEDIIIYLGSLGKQNAITTEALASTYKQWSLVHQQSTIPTAREYHNLSTRRTALKYPPNRQQAISSLQPPNMDLLKVPEVDTKMEGRPMSDEDMEDVGRRYRERRRQYKLSLPSIQYLENCRLVRSGTKQFDDHCLPTTISGEIEELLNMTRRDNFLVYLQCWELCEAYGLPLTEDILMRALLYPGDRIISLKEEVRPIRQPGGYYIDDRIVHSLAGFKNLHKHGEKETDKKTSKKMKEMHFLDFEEFTGKLKSKRLRGPSRTHPNHFWPGHLLDKLRLYLPTVARDRSLAIFSCIEHKPPAYSAVYNSKDWWPMKDLNYMTYAYYDAKKVYFIN", "length": 675 }, "evidence": [ { "id": "A0A8V1ADU3", "url": "https://omabrowser.org/oma/group/A0A8V1ADU3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1SPK5-1", "protein_name": "EF-hand calcium binding domain 12", "gene_name": "EFCAB12", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDDSSEEYEALFRSLLAFYQSKSLFDDENTSKDRVFNPELVIAHCFKQFKQEDFHLPRSRRRIFILPPKEDAMPANPTPQTQAPPQPSPSLEALKIGDVQEQPEDSVWLSQRLKLRQDLESFGNIEKWLQNKPRLTPSEAKVLHWIHKEHDDWLMAQQATTARATKKKTLRPSRLLVPQLRLPRPPALSALYAYLHSQKIKILEIFNKVDRGENQRISREEFIMALKAVGAPLKSRDVEDIVIYLSSLGKHNSITTDSLTSTYKQWSLAQQKSTLATAAEYYRPAKQSASPQSPSKKQRENSTPQPPKMDLLTVPVVDMGTEARPMTLEEMEDVGKRYRERKRQSKLEVPSIQYTERCRLVRSGNEHFDEHCLPSTIHGEMGEIINRSRTDTFLVYLQCWKLCEAYGLPLTEDILMRALLYPGDKIIFQKDQVRPIRQPGGYYSDLRTFSPNLALLRFQGTSQPTDKKPDNRKMPTKNKKIHFKEFEEFTRKLKEKRPSGPQRTHPNFFWPGHLLDKLQLYLPTMTVDRSLALFSCVRRTPQAYSVTYHPNHWWPIKAMNYMTCAYYDAPEIYHIN", "length": 576 }, "evidence": [ { "id": "A0A8V1ADU3", "url": "https://omabrowser.org/oma/group/A0A8V1ADU3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q6NXP0-1", "protein_name": "EF-hand calcium-binding domain-containing protein 12", "gene_name": "EFCAB12", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDDDYEAYHSLFLSLLGLCPSKTPINENAPVFDPEPVIAHCFKQFQQKDFRLPQTRRRIIMVPRKEDQTPLNPASQPQAPPKPIPSFKVLEARDIQEQPEDRKTWLSQRSKLRQELESFGDVKRWLENKPSITPSEAKVLHMIHEEQSAQPNASQATTRTTRKKAPRLSRLSRQMVPQLQLPEPPALSVMYSYLHSRKIKILEIFHKVGQGENQRITREEFIAAVKAVGVPLKNQEVEDIVIYLSSLGKHNTITMDILANTYKQWSMAQQRSSLATAREHYILAKHRDSLKGPLKKQEVDSAPQLPKVDLLTVPAVDTQMETRPMTLEEMEEVGKRYRERQRQHKLTIPSIQYTEQCHLVRCGNRHFDEHCLPSTIHGDMRELIDSARRHNFLVYLQCWKLCKSYGLPLTEDILMKALLYPGDKIIFQMDKVCPIRQPGGYYSDWKVFSPNLALLRSQGPGKSKRTDKKTPKKSKKMRFKEFEEFTRKLKVKRSSGLQQTHPNSFWPGHLLDKLQLYLPTVATDRSLALFSCVQHQPHVYPATYHPDHWWPLRNKNYMTHAHYDAAKVYYIN", "length": 572 }, "evidence": [ { "id": "A0A8V1ADU3", "url": "https://omabrowser.org/oma/group/A0A8V1ADU3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "V9GXH0-1", "protein_name": "EF-hand calcium binding domain 12", "gene_name": "Efcab12", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRSILKKRPGEETVSCLPPNKCLAKVCNLRGGGYKQTRRVGCQKTHALRKPPPHPSNASQWDAGLSSHLSKAHSQNVAETLAKHSGKQKKSSRLWEAQKAEERKSRVTFGLTITDAGSHHSFTSIEDDLDETTSKVPVFKPELVTAHCFRQLKQKDFRLPKSRRRIIIVPGTKDQVPARPTVPPEAPLPLMPSFRVLDTSDTQELPVDKKVWLNQRAKLRRQLETFGDVKTWLDNKPNITSSEFRVLSMIRQEQKTPKHTLISIRRAKDRALRHVRLIAPQLRLPKPPVLSDMYAYLRSRKIKILEIFSKGERGENQRISREEFLMALKAVGVPLKNQELEDIIIYLGSLGKQNTITTEALASTYKQWSLAQQKSTIPSAKEYYKLSAKRTPLKHSPKEQQATSSSQPRKMDLLKVPEVDTKMEGRPMSEEDMEDVGRRYRERRRQYKLSLPSIQYMENCRLVRSGTKEFDNHCLPTTISGEMEELLNVTRRDNFLVYLQCWELCEAYGLPLTEEILMRALLYPGDKIITLKEEVRPIRQPGGYYIDQRIVYSLAARRSPRRHGGKKRDKKTSKKMKKMHFDDFEELTGKLKLQRLSPSDTHPNHFWPGHLLDKLRLYLPTVAKDQSLAIFSCVEHKPPAYPAIYHSKNYWPMKDFSYMTHAYYDANKVYSIN", "length": 673 }, "evidence": [ { "id": "A0A8V1ADU3", "url": "https://omabrowser.org/oma/group/A0A8V1ADU3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 183, "end_pos": 185, "annotation": "n_glycosylation_sequon" }, { "start_pos": 307, "end_pos": 309, "annotation": "n_glycosylation_sequon" }, { "start_pos": 334, "end_pos": 336, "annotation": "n_glycosylation_sequon" }, { "start_pos": 615, "end_pos": 617, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1ADU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADU3" }, { "id": "PF14908", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14908" }, { "id": "PF18289", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18289" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CCDC81 HU", "eco_id": "ECO_0000259", "start_pos": 22, "end_pos": 96, "start_aa": "Thr", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 183, "end_pos": 185 }, { "start_pos": 307, "end_pos": 309 }, { "start_pos": 334, "end_pos": 336 }, { "start_pos": 615, "end_pos": 617 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1ADU8-1", "uniprot_ac": "A0A8V1ADU8", "uniprot_id": "A0A8V1ADU8_CHICK", "mass": { "chemical_mass": 39842.0, "monoisotopic_mass": 39842.0 }, "refseq": {}, "gene_names": [ { "name": "GOLPH3L", "type": "recommended", "evidence": [ { "id": "A0A8V1ADU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADU8" } ] } ], "protein_names": [ { "name": "Golgi phosphoprotein 3 like", "type": "synonym", "evidence": [ { "id": "A0A8V1ADU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADU8/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADU8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADU8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "GOLPH3L", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADU8", "locus": { "chromosome": "25", "start_pos": 2248688, "end_pos": 2244673, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028452", "url": "https://www.ensembl.org/id/ENSGALG00010028452" } ] } } ], "crossref": [ { "id": "A0A8V1ADU8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1ADU8", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR008628", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008628", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038261", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038261", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ADU8", "url": "https://www.orthodb.org/?gene=A0A8V1ADU8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AKH0", "url": "https://www.orthodb.org/?gene=A0A8V1AKH0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12704", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12704", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12704:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12704:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05719", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05719", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1ADU8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADU8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ADU8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADU8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AKH0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKH0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AKH0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKH0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MALWALQPCECEGLVAAPGVQNPTQGLEPSQPGRPQGRMSPWWLRFLVPFLKVQSSESTRHRVAAAAPCCGSAALGQVGMTTLTRRGWRGDKRTEPEEDAAADREQPDDDSDNSKATRLTLMEEVLLLGLQDKEGYPSFWNDCLSPGLRGGILIELALRGRIHLEPLTARKKRLLDRKVLLKSAAPTGDVLLDETLRHIKASESTETVQTWIELLTGETWNPFKLQYQLRNVRERVAKGLVEKGILTTGKQSFLLFDMTTHPVCDTTEKQRLLKKLQGSVLERWTGDLRRMDHRLLALLVLAHASDVLEKALGSLEDTQYEMAMSRAKDVLEADAELEAAQGRGTEVIWAVLAAFSRA", "length": 358, "header": "tr|A0A8V1ADU8-1|A0A8V1ADU8_CHICK Isoform 1 of Golgi phosphoprotein 3 like OS=Gallus gallus OX=9031 GN=GOLPH3L PE=1 SV=1 CANONICAL=A0A8V1ADU8-1" }, "isoforms": [ { "isoform_ac": "A0A8V1ADU8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADU8/entry#A0A8V1ADU8-1", "sequence": { "sequence": "MALWALQPCECEGLVAAPGVQNPTQGLEPSQPGRPQGRMSPWWLRFLVPFLKVQSSESTRHRVAAAAPCCGSAALGQVGMTTLTRRGWRGDKRTEPEEDAAADREQPDDDSDNSKATRLTLMEEVLLLGLQDKEGYPSFWNDCLSPGLRGGILIELALRGRIHLEPLTARKKRLLDRKVLLKSAAPTGDVLLDETLRHIKASESTETVQTWIELLTGETWNPFKLQYQLRNVRERVAKGLVEKGILTTGKQSFLLFDMTTHPVCDTTEKQRLLKKLQGSVLERWTGDLRRMDHRLLALLVLAHASDVLEKALGSLEDTQYEMAMSRAKDVLEADAELEAAQGRGTEVIWAVLAAFSRA", "length": 358, "header": "tr|A0A8V1ADU8-1|A0A8V1ADU8_CHICK Isoform 1 of Golgi phosphoprotein 3 like OS=Gallus gallus OX=9031 GN=GOLPH3L PE=1 SV=1 CANONICAL=A0A8V1ADU8-1" }, "locus": { "chromosome": "25", "start_pos": 2247824, "end_pos": 2244787, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068908.1", "url": 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"A0A8V1ADX0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADX0" } ], "pmid": "" }, { "name": "cilium assembly", "id": "GO:0060271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060271", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADX0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADX0" } ], "pmid": "" }, { "name": "endocytic recycling", "id": "GO:0032456", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032456", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADX0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADX0" } ], "pmid": "" }, { "name": "positive regulation of Wnt protein secretion", "id": "GO:0061357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061357", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADX0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADX0" } ], "pmid": "" }, { "name": "positive regulation of homophilic cell adhesion", "id": "GO:1903387", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903387", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADX0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADX0" } ], "pmid": "" }, { "name": "positive regulation of early endosome to late endosome transport", "id": "GO:2000643", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000643", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADX0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADX0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "endosome", "id": "GO:0005768", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005768", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADX0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADX0" } ], "pmid": "" }, { "name": "early endosome", "id": "GO:0005769", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005769", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADX0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADX0" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": 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phosphatase activity", "id": "GO:0004725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004725", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADX0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADX0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1254, "end_pos": 1256, "annotation": "n_glycosylation_sequon" }, { "start_pos": 656, "end_pos": 658, "annotation": "n_glycosylation_sequon" }, { "start_pos": 843, "end_pos": 845, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1ADX0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADX0" }, { "id": "PS51180", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51180" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BRO1", "eco_id": 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[], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.1.3.48", "ec_name": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "3.1.3.48", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48" }, { "id": "3.1.3.48", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.1.3.48" } ] } ], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 347, 1194 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1254, "end_pos": 1256 }, { "start_pos": 656, "end_pos": 658 }, { "start_pos": 843, "end_pos": 845 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": 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"sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": 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], "protein_names": [ { "name": "SUZ12 polycomb repressive complex 2 subunit", "type": "synonym", "evidence": [ { "id": "A0A8V1ADX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADX2/entry#names_and_taxonomy" } ] }, { "name": "polycomb protein SUZ12", "type": "synonym", "evidence": [ { "id": "XP_004946226", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004946226" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052549.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004946226.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004946226", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004946226" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADX2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADX2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SUZ12", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADX2", "locus": { "chromosome": "18", "start_pos": 7239791, "end_pos": 7220340, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029591", "url": "https://www.ensembl.org/id/ENSGALG00010029591" } ] } } ], "crossref": [ { "id": "A0A8V1ADX2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1ADX2", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd21551", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21551", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd21740", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21740", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd21750", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21750", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "417406", "url": "https://www.ncbi.nlm.nih.gov/gene/417406", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019135", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019135", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057540", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057540", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:417406", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417406", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VDGMLTK", "url": "https://omabrowser.org/oma/group/VDGMLTK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ADX2", "url": "https://www.orthodb.org/?gene=A0A8V1ADX2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22597", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22597", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22597:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22597:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF09733", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09733", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23320", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23320", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-212300", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-212300", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-2559580", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2559580", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-4551638", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4551638", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-8943724", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8943724", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-8953750", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8953750", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9764725", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9764725", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9909649", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9909649", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_004946226", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004946226", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1ADX2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADX2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ADX2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADX2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAPQKHGGGAGPSSGSAGGAAGGGGGGGGGGGGGGGGGGGGGGGSSSSSSGGGGFVGSAAAAAPAGKSGGAAGGGGGGGGGSGYSGGSSASSAAAAATAALPPVKKPKMEQIQADHELFLQAFEKPTQIYRFLRTRNLIAPIFLHRTLTYMSHRNSRTNIKRKTFKVDDMLSKVEKMKGEQESHSLSAHLQLTFTGFFHKNDKPSQNSENEQNSVTLEVLLVKVCHKKRKDVSCPIRQVPTGKKQVPLNPDLSQIKPGNFPSLAVSSNEFEPSNSHMVKSYSLLFRVTRPGRRDFNGLINGETNENIDVNEELPARRKRNSSNREDGEKTFVAQMTVFDKNRRLQLLDGEYEVAMQEMEECPISKKRATWETILDGKRLPPFETFSQGPTLQFTLRWTGDTNDKSTAPIAKPLATRNSESLPQENKPNSVKPTQTIAVKESLPADLQTRKERDVLNEPRQKLRIFYQFLYNNNTRQQTEARDDLHCPWCTLNCRKLYSLLKHLKLCHSRFIFNYVYHPKGARIDVSINECYDGSYAGNPQDIHRQPGFAFSRNGPVKRTPITHILVCRPKRTKASMSEFLESEDGEVEQQRTYSSGHNRLYFHSDTCLPLRPQEMEVDSEDEKDPEWLREKTITQIEEFSDVNEGEKEVMKLWNLHVMKHGFIADNQMNHACMLFVENYGQKIIKKNLCRNFMLHLVSMHDFNLISIMSIDKAVARLREMQQKLEKGESTSPMDEESSEEQSGTTNGYSENNMRERISEMDSISGVTKQSKKQKL", "length": 775, "header": "tr|A0A8V1ADX2-1|A0A8V1ADX2_CHICK Isoform 1 of SUZ12 polycomb repressive complex 2 subunit OS=Gallus gallus OX=9031 GN=SUZ12 PE=1 SV=1 CANONICAL=A0A8V1ADX2-1" }, "isoforms": [ { "isoform_ac": "A0A8V1ADX2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADX2/entry#A0A8V1ADX2-1", "sequence": { "sequence": "MAPQKHGGGAGPSSGSAGGAAGGGGGGGGGGGGGGGGGGGGGGGSSSSSSGGGGFVGSAAAAAPAGKSGGAAGGGGGGGGGSGYSGGSSASSAAAAATAALPPVKKPKMEQIQADHELFLQAFEKPTQIYRFLRTRNLIAPIFLHRTLTYMSHRNSRTNIKRKTFKVDDMLSKVEKMKGEQESHSLSAHLQLTFTGFFHKNDKPSQNSENEQNSVTLEVLLVKVCHKKRKDVSCPIRQVPTGKKQVPLNPDLSQIKPGNFPSLAVSSNEFEPSNSHMVKSYSLLFRVTRPGRRDFNGLINGETNENIDVNEELPARRKRNSSNREDGEKTFVAQMTVFDKNRRLQLLDGEYEVAMQEMEECPISKKRATWETILDGKRLPPFETFSQGPTLQFTLRWTGDTNDKSTAPIAKPLATRNSESLPQENKPNSVKPTQTIAVKESLPADLQTRKERDVLNEPRQKLRIFYQFLYNNNTRQQTEARDDLHCPWCTLNCRKLYSLLKHLKLCHSRFIFNYVYHPKGARIDVSINECYDGSYAGNPQDIHRQPGFAFSRNGPVKRTPITHILVCRPKRTKASMSEFLESEDGEVEQQRTYSSGHNRLYFHSDTCLPLRPQEMEVDSEDEKDPEWLREKTITQIEEFSDVNEGEKEVMKLWNLHVMKHGFIADNQMNHACMLFVENYGQKIIKKNLCRNFMLHLVSMHDFNLISIMSIDKAVARLREMQQKLEKGESTSPMDEESSEEQSGTTNGYSENNMRERISEMDSISGVTKQSKKQKL", "length": 775, "header": "tr|A0A8V1ADX2-1|A0A8V1ADX2_CHICK Isoform 1 of SUZ12 polycomb repressive complex 2 subunit OS=Gallus gallus OX=9031 GN=SUZ12 PE=1 SV=1 CANONICAL=A0A8V1ADX2-1" }, "locus": { "chromosome": "18", "start_pos": 7237692, "end_pos": 7220539, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071530.1", "url": "https://www.ensembl.org/id/ENSGALT00010071530.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044220.1", "url": "https://www.ensembl.org/id/ENSGALP00010044220.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:417406", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417406", "resource": "KEGG Pathway" }, { "id": "R-GGA-212300", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-212300", "resource": "Reactome", "description": "PRC2 methylates histones and DNA" }, { "id": "R-GGA-2559580", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2559580", "resource": "Reactome", "description": "Oxidative Stress Induced Senescence" }, { "id": "R-GGA-4551638", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4551638", "resource": "Reactome", "description": "SUMOylation of chromatin organization proteins" }, { "id": "R-GGA-8943724", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8943724", "resource": "Reactome", "description": "Regulation of PTEN gene transcription" }, { "id": "R-GGA-8953750", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8953750", "resource": "Reactome", "description": "Transcriptional Regulation by E2F6" }, { "id": "R-GGA-9764725", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9764725", "resource": "Reactome", "description": "Negative Regulation of CDH1 Gene Transcription" }, { "id": "R-GGA-9909649", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9909649", "resource": "Reactome", "description": "Regulation of PD-L1(CD274) transcription" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1M792-1", "protein_name": "SUZ12 polycomb repressive complex 2 subunit", "gene_name": "SUZ12", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAPQKHGGGGGGGSGPSAGSGGGGFGGSAAVAAATASGGKSGGGGCGGGGSYSASSSSSAAAAAGAAVLPVKKPKMEHVQADHELFLQAFEKPTQIYRFLRTRNLIAPIFLHRTLTYMSHRNSRTNIKRKTFKVDDMLSKVEKMKGEQESHSLSAHLQLTFTGFFHKNDKPSQNSENEQNSVTLEVLLVKVCHKKRKDVSCPIRQVPTGKKQVPLNPDLNQTKPGNFPSLAVSSNEFEPSNSHMVKSYSLLFRVTRPGRREYNGMINGETNENIDVNEELPARRKRNREDGEKTFVAQMTVFDKNRRLQLLDGEYEVAMQEMEECPISKKRATWETILDGKRLPPFETFSQGPTLQFTLRWTGETNDKSTAPIAKPLATRNSESLHQENKPGSVKPTQTIAVKESLTTDLQTRKEKDTSNENRQKLRIFYQFLYNNNTRQQTEARDDLHCPWCTLNCRKLYSLLKHLKLCHSRFIFNYVYHPKGARIDVSINECYDGSYAGNPQDIHRQPGFAFSRNGPVKRTPITHILVCRPKRTKASMSEFLESEDGEVEQQRTYSSGHNRLYFHSDTCLPLRPQEMEVDSEDEKDPEWLREKTITQIEEFSDVNEGEKEVMKLWNLHVMKHGFIADNQMNHACMLFVENYGQKIIKKNLCRNFMLHLVSMHDFNLISIMSIDKAVTKLREMQQKLEKGESASPANEEVTEEQNGTANGFSEINSKEKALETDGVSGVSKQSKKQKL", "length": 739 }, "evidence": [ { "id": "A0A8V1ADX2", "url": "https://omabrowser.org/oma/group/A0A8V1ADX2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A8I6AIG5-1", "protein_name": "SUZ12 polycomb repressive complex 2 subunit", "gene_name": "Suz12", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAPQKHGGGGGGGSGPSAGSGGGGFGGSAAAVAAAVASGGKSGGGGCGGGGGYSASSSSAAAAGAAVLPVKKPKMEHVQADHELFLQAFEKPTQIYRFLRTRNLIAPIFLHRTLTYMSHRNSRTNIKRKTFKVDDMLSKVEKMKGEQESHSLSAHLQLTFTGFFHKNDKPSQNSENEQNSVTLEVLLVKVCHKKRKDVSCPIRQVPTGKKQVPLNPDLNQTKPGNFPSLAVSSNEFEPSNSHMVKSYSLLFRVTRPGRREFNGMINGETNENIDVSEELPARRKRNREDGEKTFVAQMTVFDKNRRLQLLDGEYEVAMQEMEECPISKKRATWETILDGKRLPPFETFSQGPTLQFTLRWTGETNDKSTAPVAKPLATRNSESLHQENKPGSVKPAQTIAVKETLTTEMQTRKEKDTSNETRQKLRIFYQFLYNNNTRQQTEARDDLHCPWCTLNCRKLYSLLKHLKLCHSRFIFNYVYHPKGARIDVSINECYDGSYAGNPQDIHRQPGFAFSRNGPVKRTPITHILVCRPKRTKASMSEFLESEDGEVEQQRTYSSGHNRLYFHSDTCLPLRPQEMEVDSEDEKDPEWLREKTITQIEEFSDVNEGEKEVMKLWNLHVMKHGFIADNQMNHACMLFVENYGQKIIKKNLCRNFMLHLVSMHDFNLISIMSIDKAVTKLREMQQKLEKGESAAPANEDIAEEQNGTANGFSETNSKEKALETDGVSGVPKQSKKQKL", "length": 738 }, "evidence": [ { "id": "A0A8V1ADX2", "url": "https://omabrowser.org/oma/group/A0A8V1ADX2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "B0R1D5-1", "protein_name": "Polycomb protein suz12-B", "gene_name": "suz12b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAPQKYSAQVMNSKANGAVYPSSGVSSLKKPKIEQLQADHELFLQAFEKPTQIYRFLRTRNLITPVLLHRTLTFMSHRNSRTNAKRKSFKVDDLLSSVEKMKGEPESPSLTSHLQLTFTGFFHKNVKPCQNSENEQNSVSLEVLLVKVCHKKRKDVSCPIKQVPTGKKQVPLNPDLSQTKPGAFPSLLVSSNEFEPSNSHMVKSYSLLFRVSHTGKRDPNGFISCEADENIDVKDEIPPRRKRNSSLRGDGETTETFVAQMTVFDKNRRLQLLDGEYEVSMQQIEDCPVSKKRATWETILDGKRLPPFETFSQGPTLQFTLRWTADPSDPSTAPVAKPLSTRNSDTSTTESRISTLRPAPVAVKESVSTSMQSRIEHSPCEPRQKLRIFYQFLYNNNTRQQTEARDDLHCPWCTLNCRKLYSLLKHLKLSHSRFIFNYVPHPKGARIDVSINECYDGSYVGNPQDIHSQPGFAFSRNGPVKRTAVTHILVCRPKRTKPSLSEFLESEDGEPEQQRTYVSGHNRLYFHSDSCMPLRPQEMEVDSEDERDPEWLQEKTTTQIEEFTDVNEGEKEVMKLWNLHVMKNGFIADNQMSQASMLFVEICGPHIIRRNLCRNFLLHLVNLHDFNLVTIATIDQAMARLKEIEESFPELEAGQESLDATCNGHSLSLGFSLHGKCTKLES", "length": 682 }, "evidence": [ { "id": "A0A8V1ADX2", "url": "https://omabrowser.org/oma/group/A0A8V1ADX2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q15022-1", "protein_name": "Polycomb protein SUZ12", "gene_name": "SUZ12", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAPQKHGGGGGGGSGPSAGSGGGGFGGSAAVAAATASGGKSGGGSCGGGGSYSASSSSSAAAAAGAAVLPVKKPKMEHVQADHELFLQAFEKPTQIYRFLRTRNLIAPIFLHRTLTYMSHRNSRTNIKRKTFKVDDMLSKVEKMKGEQESHSLSAHLQLTFTGFFHKNDKPSPNSENEQNSVTLEVLLVKVCHKKRKDVSCPIRQVPTGKKQVPLNPDLNQTKPGNFPSLAVSSNEFEPSNSHMVKSYSLLFRVTRPGRREFNGMINGETNENIDVNEELPARRKRNREDGEKTFVAQMTVFDKNRRLQLLDGEYEVAMQEMEECPISKKRATWETILDGKRLPPFETFSQGPTLQFTLRWTGETNDKSTAPIAKPLATRNSESLHQENKPGSVKPTQTIAVKESLTTDLQTRKEKDTPNENRQKLRIFYQFLYNNNTRQQTEARDDLHCPWCTLNCRKLYSLLKHLKLCHSRFIFNYVYHPKGARIDVSINECYDGSYAGNPQDIHRQPGFAFSRNGPVKRTPITHILVCRPKRTKASMSEFLESEDGEVEQQRTYSSGHNRLYFHSDTCLPLRPQEMEVDSEDEKDPEWLREKTITQIEEFSDVNEGEKEVMKLWNLHVMKHGFIADNQMNHACMLFVENYGQKIIKKNLCRNFMLHLVSMHDFNLISIMSIDKAVTKLREMQQKLEKGESASPANEEITEEQNGTANGFSEINSKEKALETDSVSGVSKQSKKQKL", "length": 739 }, "evidence": [ { "id": "A0A8V1ADX2", "url": "https://omabrowser.org/oma/group/A0A8V1ADX2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q80U70-1", "protein_name": "Polycomb protein Suz12", "gene_name": "Suz12", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAPQKHGGGGGGGSGPSAGSGGGGFGGSAAAVAAAASGGKSGGGGCGGGGSYSASSSSAAAAAAAAGAAVLPVKKPKMEHVQADHELFLQAFEKPTQIYRFLRTRNLIAPIFLHRTLTYMSHRNSRTSIKRKTFKVDDMLSKVEKMKGEQESHSLSAHLQLTFTGFFHKNDKPSQNSENEQNSVTLEVLLVKVCHKKRKDVSCPIRQVPTGKKQVPLNPDLNQTKPGNFPSLAVSSNEFEPSNSHMVKSYSLLFRVTRPGRREFNGMINGETNENIDVSEELPARRKRNREDGEKTFVAQMTVFDKNRRLQLLDGEYEVAMQEMEECPISKKRATWETILDGKRLPPFETFSQGPTLQFTLRWTGETNDKSTAPVAKPLATRNSESLHQENKPGSVKPAQTIAVKETLTTELQTRKEKDNSNESRQKLRIFYQFLYNNNTRQQTEARDDLHCPWCTLNCRKLYSLLKHLKLCHSRFIFNYVYHPKGARIDVSINECYDGSYAGNPQDIHRQPGFAFSRNGPVKRTPITHILVCRPKRTKASMSEFLESEDGEVEQQRTYSSGHNRLYFHSDTCLPLRPQEMEVDSEDEKDPEWLREKTITQIEEFSDVNEGEKEVMKLWNLHVMKHGFIADNQMNHACMLFVENYGQKIIKKNLCRNFMLHLVSMHDFNLISIMSIDKAVTKLREMQQKLEKGESATPSNEEIAEEQNGTANGFSETNSKEKALETDGVSGVPKQSKKQKL", "length": 741 }, "evidence": [ { "id": "A0A8V1ADX2", "url": "https://omabrowser.org/oma/group/A0A8V1ADX2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NJG9-1", "protein_name": "Polycomb protein Su(z)12", "gene_name": "Su(z)12", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MAPAKKREKDSNPDGSAANGIIGLTHGAPDASNAGSTVPPTAEGQVKLNGHQQEQELFLQAFEKPTQIYRYLRNRHETNPIFLNRTLSYMKERMSRNNKKRISFQVNSMLESITQKSEAVSQNYLHVIYDSLHEKLPARLDNESGEDLLQEQLLCEAGESVSVETTLYKITRSKRKDSTLDFQELLSKCSQIVYNPKDRVGEHATISIPLQTMRPMGEQHTLYKLLFRIKVLSPSTCNDENAETPPNKRSRPNEKMFGSELILYEKSSGFITEGEYEAMLQPLNSTSIKSFSPKKCTWETMPDSYIPLSLTYDVYQQSPMLKFHLTLSNEQLPEMISAPELQRYVQHLDAVAEMNYNNNNYNNNNNCSGLKNGSGGGNSTVCKTTPEHIQIVYNFMYSNNTRQQTEYTQELNCPWCGLDCLRLYALLKHLKLCHARFNFTYQPAGSGARIDVTINDAYDGSYAGSPYDLAGPSGSSFARTCGPVRRTSVTSLMVCRPRRQKTCLDEFLELDEDEISNQRSYITGHNRLYHHTETCLPVHPKELDIDSEGESDPLWLRQKTIQMIDEFSDVNEGEKELMKLWNLHVMRHGFVGDCQLPIACEMFLDAKGTEIVRKNLYRNFILHMCSLFDYGLIAAETVYKTVQKLQGLLSKYAAGQELMQRQREEQLKYWLDVGMHKKQEDPKTLKSPQKPAPPADQASTSSASTSGSGSGSSSMQPPKRMPAHLKRGSAASSPGVQSKGTENGTNGSNSSSSNSKNVAKKSADQPLSTLANTRERRSEYGQKRNVSGSRLAATPASKRKLSSKDNTVLNKRQRYSDGSPGTGIGNGHGGGSGSGANRNKSNNHSLPATSNNASSSSSNSKRAIARRRSTSERTKASGSTGGGAGGVRTRLSVPAKYERR", "length": 900 }, "evidence": [ { "id": "A0A8V1ADX2", "url": "https://omabrowser.org/oma/group/A0A8V1ADX2/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADX2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADX2" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADX2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADX2" } ], "pmid": "" }, { "name": "negative regulation of cell differentiation", "id": "GO:0045596", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045596", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADX2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADX2" } ], "pmid": "" }, { "name": "facultative heterochromatin formation", "id": "GO:0140718", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140718", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADX2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADX2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 9, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADX2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADX2" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADX2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADX2" } ], "pmid": "" }, { "name": "nuclear body", "id": "GO:0016604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016604", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADX2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADX2" } ], "pmid": "" }, { "name": "ESC/E(Z) complex", "id": "GO:0035098", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035098", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADX2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADX2" } ], "pmid": "" }, { "name": "protein-DNA complex", "id": "GO:0032993", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032993", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADX2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADX2" } ], "pmid": "" }, { "name": "chromatin silencing complex", "id": "GO:0005677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005677", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADX2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADX2" } ], "pmid": "" }, { "name": "ribonucleoprotein complex", "id": "GO:1990904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990904", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADX2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADX2" } ], "pmid": "" }, { "name": "RSC-type complex", "id": "GO:0016586", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016586", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADX2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADX2" } ], "pmid": "" }, { "name": "sex chromatin", "id": "GO:0001739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001739", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADX2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADX2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 8, "go_terms": [ { "name": "enzyme activator activity", "id": "GO:0008047", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008047", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADX2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADX2" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADX2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADX2" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADX2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADX2" } ], "pmid": "" }, { "name": "chromatin DNA binding", "id": "GO:0031490", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031490", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADX2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADX2" } ], "pmid": "" }, { "name": "promoter-specific chromatin binding", "id": "GO:1990841", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990841", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADX2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADX2" } ], "pmid": "" }, { "name": "transcription corepressor binding", "id": "GO:0001222", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001222", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADX2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADX2" } ], "pmid": "" }, { "name": "histone H3K9me2/3 reader activity", "id": "GO:0062072", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0062072", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADX2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADX2" } ], "pmid": "" }, { "name": "lncRNA binding", "id": "GO:0106222", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106222", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADX2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADX2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 320, "end_pos": 322, "annotation": "n_glycosylation_sequon" }, { "start_pos": 472, "end_pos": 474, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1ADX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADX2" }, { "id": "PF23320", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23320" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Polycomb protein SUZ12-like zinc finger", "eco_id": "ECO_0000259", "start_pos": 463, "end_pos": 530, "start_aa": "Arg", "end_aa": "Cys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1ADX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADX2" }, { "id": "PF09733", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09733" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Polycomb protein VEFS-Box", "eco_id": "ECO_0000259", "start_pos": 589, "end_pos": 708, "start_aa": "Gln", "end_aa": "Met", "glycosite_overlap": "" } ], "binding_sites": [], 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##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. 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"UniProtKB", "id": "A0A8V1ADX9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADX9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "structural constituent of cytoskeleton", "id": "GO:0005200", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005200", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADX9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADX9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "fertilization", "id": "GO:0009566", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009566", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADX9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADX9" } ], "pmid": "" }, { "name": "acrosome assembly", "id": "GO:0001675", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001675", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADX9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADX9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], 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"glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1ADY2-1", "uniprot_ac": "A0A8V1ADY2", "uniprot_id": "A0A8V1ADY2_CHICK", "mass": { "chemical_mass": 49253.0, "monoisotopic_mass": 49253.0 }, "refseq": {}, "gene_names": [ { "name": "CRLF3", "type": "recommended", "evidence": [ { "id": "A0A8V1ADY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADY2" } ] } ], "protein_names": [ { "name": "Cytokine receptor-like factor 3", "type": "recommended", "evidence": [ { "id": "A0A8V1ADY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADY2/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "May play a role in the negative regulation of cell cycle progression.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AL21", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL21#function" }, { "database": "UniProtKB", "id": "ARBA00056593", "url": "https://www.uniprot.org/uniprotkb/ARBA00056593#function" }, { "database": "UniProtKB", "id": "A0A8V1APD3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APD3#function" }, { "database": "UniProtKB", "id": "A0A8V1ADY2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADY2#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADY2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADY2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CRLF3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADY2", "locus": { "chromosome": "18", "start_pos": 7241493, "end_pos": 7254747, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029594", "url": "https://www.ensembl.org/id/ENSGALG00010029594" } ] } } ], "crossref": [ { "id": "A0A8V1ADY2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1ADY2", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00063", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00063", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "417407", "url": "https://www.ncbi.nlm.nih.gov/gene/417407", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR059495", "url": "https://www.ebi.ac.uk/interpro/entry/IPR059495", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:417407", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417407", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HEWTPGF", "url": "https://omabrowser.org/oma/group/HEWTPGF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ADY2", "url": "https://www.orthodb.org/?gene=A0A8V1ADY2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AL21", "url": "https://www.orthodb.org/?gene=A0A8V1AL21", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1APD3", "url": "https://www.orthodb.org/?gene=A0A8V1APD3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PF27984", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27984", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF27985", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27985", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1ADY2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADY2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ADY2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADY2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AL21", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL21", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AL21-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL21-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1APD3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APD3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1APD3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APD3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MWGPSGGPPAAAAAHGGRDRGAAPAAGGSGEHRGGAELPAGAAAAVAGAAPGAATESATLTRDVLEQHFNDLKGTLKKLLDERLMSLLQEVDTIEQESIKPLDECQKLIEHGVSTADDLLREGESAICGDVEQHNEKLCSFTKKALHIQLDSLPEVPSLVDVPCLSAQLDDCLLTILRNEIFRHGTVASHPPVQLEEFVEKPGGILVRWCKVDDDFVPQDYRLQYRKSTANHFEDVYVGSETEFMVLHIDPNVDYQFRVCARGDGRQEWSPWSVPQIGRTTLVPHEWTAGLEGYSLSSRRNIALRNDSQSCGVLYSKAPTYFCGQTLTFRIETVGQPDRRDSLGVCVEQQNGYDSLQRDKAVCISTNGAVFVNGKEMTNQLPAVTSGSTVTFDMEVVQLGPPSTEGGNFKLRVTISSNNREVVFDWVLDQCCVSLYFGCSFSYPGWKVLVF", "length": 451, "header": "tr|A0A8V1ADY2-1|A0A8V1ADY2_CHICK Isoform 1 of Cytokine receptor-like factor 3 OS=Gallus gallus OX=9031 GN=CRLF3 PE=1 SV=1 CANONICAL=A0A8V1ADY2-1" }, "isoforms": [ { "isoform_ac": "A0A8V1ADY2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADY2/entry#A0A8V1ADY2-1", "sequence": { "sequence": "MWGPSGGPPAAAAAHGGRDRGAAPAAGGSGEHRGGAELPAGAAAAVAGAAPGAATESATLTRDVLEQHFNDLKGTLKKLLDERLMSLLQEVDTIEQESIKPLDECQKLIEHGVSTADDLLREGESAICGDVEQHNEKLCSFTKKALHIQLDSLPEVPSLVDVPCLSAQLDDCLLTILRNEIFRHGTVASHPPVQLEEFVEKPGGILVRWCKVDDDFVPQDYRLQYRKSTANHFEDVYVGSETEFMVLHIDPNVDYQFRVCARGDGRQEWSPWSVPQIGRTTLVPHEWTAGLEGYSLSSRRNIALRNDSQSCGVLYSKAPTYFCGQTLTFRIETVGQPDRRDSLGVCVEQQNGYDSLQRDKAVCISTNGAVFVNGKEMTNQLPAVTSGSTVTFDMEVVQLGPPSTEGGNFKLRVTISSNNREVVFDWVLDQCCVSLYFGCSFSYPGWKVLVF", "length": 451, "header": "tr|A0A8V1ADY2-1|A0A8V1ADY2_CHICK Isoform 1 of Cytokine receptor-like factor 3 OS=Gallus gallus OX=9031 GN=CRLF3 PE=1 SV=1 CANONICAL=A0A8V1ADY2-1" }, "locus": { "chromosome": "18", "start_pos": 7254724, "end_pos": 7244149, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071541.1", "url": "https://www.ensembl.org/id/ENSGALT00010071541.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044231.1", "url": "https://www.ensembl.org/id/ENSGALP00010044231.1" } ] } }, { "isoform_ac": "A0A8V1AL21-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADY2/entry#A0A8V1AL21-1", "sequence": { "sequence": "MEAETEARLLLQEARESIEAARSYRRELQQRLRGLHQARQQIRESATLTRDVLEQHFNDLKGTLKKLLDERLMSLLQEVDTIEQESIKPLDECQKLIEHGVSTADDLLREGESAICGDVEQHNEKLCSFTKKALHIQLDSLPEVPSLVDVPCLSAQLDDCLLTILRNEIFRHGTVASHPPVQLEEFVEKPGGILVRWCKVDDDFVPQDYRLQYRKSTANHFEDVYVGSETEFMVLHIDPNVDYQFRVCARGDGRQEWSPWSVPQIGRTTLVPHEWTAGLEGYSLSSRRNIALRNDSQSCGVLYSKAPTYFCGQTLTFRIETVGQPDRRDSLGVCVEQQNGYDSLQRDKAVCISTNGAVFVNGKEMTNQLPAVTSGSTVTFDMEVVQLGPPSTEGGNFKLRVTISSNNREVVFDWVLDQCCVSLYFGCSFSYPGWKVLVF", "length": 439, "header": "tr|A0A8V1AL21-1|A0A8V1ADY2_CHICK Computationally mapped isoform of Cytokine receptor-like factor 3 OS=Gallus gallus OX=9031 GN=CRLF3 PE=1 SV=1 CANONICAL=A0A8V1ADY2-1" }, "locus": { "chromosome": "18", "start_pos": 7254681, "end_pos": 7244149, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071540.1", "url": "https://www.ensembl.org/id/ENSGALT00010071540.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044230.1", "url": "https://www.ensembl.org/id/ENSGALP00010044230.1" } ] } }, { "isoform_ac": "A0A8V1APD3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADY2/entry#A0A8V1APD3-1", "sequence": { "sequence": "MRFAEPEGFLRWLPIRESATLTRDVLEQHFNDLKGTLKKLLDERLMSLLQEVDTIEQESIKPLDECQKLIEHGVSTADDLLREGESAICGDVEQHNEKLCSFTKKALHIQLDSLPEVPSLVDVPCLSAQLDDCLLTILRNEIFRHGTVASHPPVQLEEFVEKPGGILVRWCKVDDDFVPQDYRLQYRKSTANHFEDVYVGSETEFMVLHIDPNVDYQFRVCARGDGRQEWSPWSVPQIGRTTLVPHEWTAGLEGYSLSSRRNIALRNDSQSCGVLYSKAPTYFCGQTLTFRIETVGQPDRRDSLGVCVEQQNGYDSLQRDKAVCISTNGAVFVNGKEMTNQLPAVTSGSTVTFDMEVVQLGPPSTEGGNFKLRVTISSNNREVVFDWVLDQCCVSLYFGCSFSYPGWKVLVF", "length": 412, "header": "tr|A0A8V1APD3-1|A0A8V1ADY2_CHICK Computationally mapped isoform of Cytokine receptor-like factor 3 OS=Gallus gallus OX=9031 GN=CRLF3 PE=1 SV=1 CANONICAL=A0A8V1ADY2-1" }, "locus": { "chromosome": "18", "start_pos": 7254023, "end_pos": 7244149, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071542.1", "url": "https://www.ensembl.org/id/ENSGALT00010071542.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044232.1", "url": "https://www.ensembl.org/id/ENSGALP00010044232.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:417407", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417407", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A5G2QVN6-1", "protein_name": "Cytokine receptor-like factor 3", "gene_name": "CRLF3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDLEPELLLQEARENVEAAQSYRRELGHRLKGLQEARRQIKESASQTRDVLKQHFNDLKGTLGKLLDERLVTLLQEVDAIEQETIKPLDDCQKLIEHGVNTAEDLVQEGEIAILGGVGEQNEKLWNFTKKASHIQLDSLPEVPLLVDVPCLSAQLDDSILNIVKDHIFKHGTVASRPPVQIEELVEKPGGIIVRWCKVDDDFTAQDYRLQFRKCTSSHFEDVYVGSETEFIVLHIDPNVDYQFRVCARGDGRQEWSPWSVPQTGHSTLVPHEWTAGFEGYSLSSRRNIALRNDAESSGVLYSSAPTYFCGQTLTFRVETVGQPDRRDSLGVCAEKQNGYDSLQRDQAVCISTNGAVFVNGKEMTNQLPAVTSGSTVTFDIEAVTLGSTNNNEGGNFKLRVTISSNNREVVFDWLLDQSCGSLYFGCSFFYPWKVLVF", "length": 437 }, "evidence": [ { "id": "A0A8V1ADY2", "url": "https://omabrowser.org/oma/group/A0A8V1ADY2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8I6AEZ7-1", "protein_name": "Cytokine receptor-like factor 3", "gene_name": "Crlf3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "RVCPPHTPTLHPHTPPPPPASVNQAAAGAGRGGQSRAGRRFRCARPLGVARGSRAQSGIRRAARPDEGRDGAGARGAAAGSPGERGGGAELPAGARPAAAGAAGGAEIKESASQTRDVLKQHFSDLKGTLGKLLDERLVTLLQEVDTIEQETIKPLDDCQKLIEHGVNTADDLVREGETAILGGIEEQNDKLWNFTKKASHIQLDSLPEVPLLVDVPCLSAQLDDSILNIVKDHIFKHGAVASRPPVQIEELVEKPGGIVVRWCKVDDDFTAQDYRLQFRKCPANPFEDVYVGSETEFIVLHIDPNVDYQFRVCARGDGRQEWSPWSVPQTGHSTLVPHEWTTGFEGYSLSSRRNIALRNDAESAGVLYSSAPTYFCGQTLTFRVETVGQPDRRDSIGVCAEKQNGYESLQRDQAVCISTNGAVFVNGKEMTNQLPAVTSGSTVTFDIEAVTLGPCNNNEGGNVKLRVTISSSNREVVFDWLLEQSCGSLYFGCSFFYPGWKVLVF", "length": 506 }, "evidence": [ { "id": "A0A8V1ADY2", "url": "https://omabrowser.org/oma/group/A0A8V1ADY2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q568M3-1", "protein_name": "Cytokine receptor-like factor 3", "gene_name": "crlf3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSIEAEALLQEAKESIEAAQNYRSELQQRLHGLSQARKQVRGSASQTRKALQRHFQELQTAVSRLLIDRLNGLLQEVDNIELDSVSPLDDCQKLIEHGVSTADELLREGEAAIRCSINETEDKLGSFTKKALQIQLDSLPEVPSLVDVPCLSAQLDDSLLHMFRAHVARHGSVASHPPVQIEELVERPGGVLVRWCKVDDDFSPQDYRLQFRRSNSSQYEDAYIGKDTEFLVLHLDPHVDHLFRVCARGEGRTEWSPWSIPQTGYTTLAPHEWCPGVDGYILSSRKNIAMRSDSSAPGHGGVLYSNSPTYFCGQTLTFKITAAGQTDKRDSLGVCADSRTDTDSLQRDQAVCISTNGAVFVNGKEMTNQLPAITVGSSVTFDMEVVSLFPVNNNNPSDGGNFKLRVTIGSGNREVVFDWLLDQVLDSLFFGCSFTHPGWKVLVF", "length": 444 }, "evidence": [ { "id": "A0A8V1ADY2", "url": "https://omabrowser.org/oma/group/A0A8V1ADY2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8IUI8-1", "protein_name": "Cytokine receptor-like factor 3", "gene_name": "CRLF3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRGAMELEPELLLQEARENVEAAQSYRRELGHRLEGLREARRQIKESASQTRDVLKQHFNDLKGTLGKLLDERLVTLLQEVDTIEQETIKPLDDCQKLIEHGVNTAEDLVREGEIAMLGGVGEENEKLWSFTKKASHIQLDSLPEVPLLVDVPCLSAQLDDSILNIVKDHIFKHGTVASRPPVQIEELIEKPGGIIVRWCKVDDDFTAQDYRLQFRKCTSNHFEDVYVGSETEFIVLHIDPNVDYQFRVCARGDGRQEWSPWSVPQIGHSTLVPHEWTAGFEGYSLSSRRNIALRNDSESSGVLYSRAPTYFCGQTLTFRVETVGQPDRRDSIGVCAEKQDGYDSLQRDQAVCISTNGAVFVNGKEMTNQLPAVTSGSTVTFDIEAVTLGTTSNNEGGHFKLRVTISSNNREVVFDWLLDQSCGSLYFGCSFFYPGWKVLVF", "length": 442 }, "evidence": [ { "id": "A0A8V1ADY2", "url": "https://omabrowser.org/oma/group/A0A8V1ADY2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9Z2L7-1", "protein_name": "Cytokine receptor-like factor 3", "gene_name": "Crlf3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGAMEPEPEVLLQEARENVEAAQSYRRELGQRLQGLREAQRQIKESASQTRDVLKQHFSDLKGTLGKLLDERLVTLLQEVDTIEQETIKPLDDCQKLIEHGVNTADDLVREGEIAILGGIEEESDKLWNFTKKASHIQLDSLPEVPLLVDVPCLSAQLDDSILNIVKDHIFKHGTVASRPPVQIEELIEKPGGIIVRWCKVDDDFTAQDYRLQFRKCTANHFEDVYVGSETEFIVLHIDPNVDYQFRVCARGDGRQEWSPWSVPQTGHSTLVPHEWTTGFEGYSLSSRRNIALRNDAESSGVLYSSAPTYFCGQTLTFRVETVGQPDRRDSIGVCAERQNGYESLQRDQAVCISTNGAVFVNGKEMTNQLPAVTSGSTVTFDIEAVTLGTSNSHEGGNAKLRVTISSNNREVVFDWLLEQACGPLYFGCSFFYPGWKVLVF", "length": 442 }, "evidence": [ { "id": "A0A8V1ADY2", "url": "https://omabrowser.org/oma/group/A0A8V1ADY2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADY2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADY2" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", 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"MVGRLAVAAAAASLPEKDGDAQPRKKRREEDASVKTITRYFSPLAKAGGKVSSPPKANNILDYFKKTPAAEKAPAIAGEITAEFSDEQDCYIAPSKLKRKRKRAHLNNKRRKMKESENECIIEINCDDSVEATRLQEDSDDFIATCALGDQKGGGELAEDKKHGENFSDAVIYIKSDKKAGSEINTTKNRIRKTRKRKQKVNVDSSGSFSFENQLNEKCRKETKDKKKKVSPKVAECDVVISDPSFEVHTDDKTPQANDSIITVSFEDFLKSQGENYVEDVEEGTKPMLDSSATVNETDKSGSTSDPEKCEESQQLPLRTVTVLAQVHSVPPKSTSLHKEQKGSKKIASIFLKQKVYVEEESSPPLLESDQTEQVTQKRKSNVVIEEEELELAILETAGSDSLKMRSTLEERHQFMKAFRQPTSDVRKSGVKKAPGKAKQVIGKSSKDKKGPEGDNVLNKVLEDGLPEDDVDKCMHSSPENTRTKNKRPRKFQRKGSKRNKALGAKEKCDSSTSCCNKDKESVHNDHMKESNLNVRIPSSPKESELRRSVRQKKTDVSKTTTPKKTRSTFSEDESAWPVWTSTPKASRQSLKKSNVYKAEVITVPSDENSPIRMRFTRINATIKSNKGEAMNNEELNSKNIKISSTSKNISKAKQLVEKAKAIRHNRSKVKEDSPAPVRRSSRQQALAERKTLQENEKSVITLQSSQSNDSTTVQDVKQKNLRSLNDVLGKSKNLKVSKNSKGKLGYVPSFLGRNVRKSTDEPVVIFDDSSQDASENSQDDDQFRAKREFLMSGLPELLKRQIAKKAAAMEAYFLASSYFKTVVHVQQKDDFCPMWKLKSPSCPLLTKLRKLSTDVTNVTKIAISLGEFSTVKSELTGNCPAHMFSGHRPVFSEAFRKGLLEEIVSFNSQFPVRKYFYKFLKKQTERLLVENSIQGSRDASSNSEANQKPSDNWKETKRKRKEKEDQKSKRRKENTETELESRASRSVITPVPGGKQADAEQATRLERNKNQKADVRTEDTEYLSDTNALSGVEDVLWTEKYQPQDSSELVGNKKEIERLHSWLKEWKKRADWEEKRNQKGEKEDKEHQVLSLLNNSTDSLDSLDFKDDKSDIEEENNLCNTVLITGPPGVGKTAAVYACAQELGFKIFEVNASCQRSGRQILSQLKEATQSHQVDKKGINAYKPCFFNSCSSTKSPKKMCSPKKVISPRKPPLSPKGAGLKRSLPPKTLANYFKIPSRCKGNDGTVTAQEKNKGNAQNLWEEKNVQIKSISKEIEDGEHNRKSATSLILFEEVDIIFDEDAGFLSAIKTFMATAKRPVILTTNDPTFSLMFDGYFEEINFQTPSLINAASYLQALCLAENLRTDVKDLATLLATNNCDIRQSVLYLQFWVRSGGGYLKDKHLVLHGKDETNPADQVINSEKTTDPKIVFSQDDATPQEFPKCDSGCVETLLGLKNILLPSEDLFTFLKQRITTKENWDKLIQLLTEFQLKKVDFIYSNLEFLLPLPVNYLSNQSEASNPIPERTTIVSSKNSSVNTYCYGKSNSGRKSKKTKNKKRLEELDDSDLFDTGLNYSAEFITLPSDSPTPCAEVNEEESKLMNNRNEMKSKTPSNDRRSALVLQCLNSVTEFVEDMSFLDCCVNSTVKEPLEFSKDEGFNWMNGKIKNGLCDEFSIENTDWWSSQSCSEIKAAIEALSFNKCSVSISQNLEASLSTNNTPESDQLEGLTLRMSDTRNSVSFNQSADLSIHKKAQKRLAVIRTVFSRTPLNLGNKQASILEYLPTLRSICRSEKLKEQGKTKRRFLHYLEGIHLEIPRQVINSLSLDFP", "length": 1825, "header": "tr|A0A8V1ADY7-1|A0A8V1ADY7_CHICK Isoform 1 of ATPase family, AAA domain containing 5 OS=Gallus gallus OX=9031 GN=ATAD5 PE=4 SV=1 CANONICAL=A0A8V1ADY7-1" }, "isoforms": [ { "isoform_ac": "A0A8V1ADY7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADY7/entry#A0A8V1ADY7-1", "sequence": { "sequence": "MVGRLAVAAAAASLPEKDGDAQPRKKRREEDASVKTITRYFSPLAKAGGKVSSPPKANNILDYFKKTPAAEKAPAIAGEITAEFSDEQDCYIAPSKLKRKRKRAHLNNKRRKMKESENECIIEINCDDSVEATRLQEDSDDFIATCALGDQKGGGELAEDKKHGENFSDAVIYIKSDKKAGSEINTTKNRIRKTRKRKQKVNVDSSGSFSFENQLNEKCRKETKDKKKKVSPKVAECDVVISDPSFEVHTDDKTPQANDSIITVSFEDFLKSQGENYVEDVEEGTKPMLDSSATVNETDKSGSTSDPEKCEESQQLPLRTVTVLAQVHSVPPKSTSLHKEQKGSKKIASIFLKQKVYVEEESSPPLLESDQTEQVTQKRKSNVVIEEEELELAILETAGSDSLKMRSTLEERHQFMKAFRQPTSDVRKSGVKKAPGKAKQVIGKSSKDKKGPEGDNVLNKVLEDGLPEDDVDKCMHSSPENTRTKNKRPRKFQRKGSKRNKALGAKEKCDSSTSCCNKDKESVHNDHMKESNLNVRIPSSPKESELRRSVRQKKTDVSKTTTPKKTRSTFSEDESAWPVWTSTPKASRQSLKKSNVYKAEVITVPSDENSPIRMRFTRINATIKSNKGEAMNNEELNSKNIKISSTSKNISKAKQLVEKAKAIRHNRSKVKEDSPAPVRRSSRQQALAERKTLQENEKSVITLQSSQSNDSTTVQDVKQKNLRSLNDVLGKSKNLKVSKNSKGKLGYVPSFLGRNVRKSTDEPVVIFDDSSQDASENSQDDDQFRAKREFLMSGLPELLKRQIAKKAAAMEAYFLASSYFKTVVHVQQKDDFCPMWKLKSPSCPLLTKLRKLSTDVTNVTKIAISLGEFSTVKSELTGNCPAHMFSGHRPVFSEAFRKGLLEEIVSFNSQFPVRKYFYKFLKKQTERLLVENSIQGSRDASSNSEANQKPSDNWKETKRKRKEKEDQKSKRRKENTETELESRASRSVITPVPGGKQADAEQATRLERNKNQKADVRTEDTEYLSDTNALSGVEDVLWTEKYQPQDSSELVGNKKEIERLHSWLKEWKKRADWEEKRNQKGEKEDKEHQVLSLLNNSTDSLDSLDFKDDKSDIEEENNLCNTVLITGPPGVGKTAAVYACAQELGFKIFEVNASCQRSGRQILSQLKEATQSHQVDKKGINAYKPCFFNSCSSTKSPKKMCSPKKVISPRKPPLSPKGAGLKRSLPPKTLANYFKIPSRCKGNDGTVTAQEKNKGNAQNLWEEKNVQIKSISKEIEDGEHNRKSATSLILFEEVDIIFDEDAGFLSAIKTFMATAKRPVILTTNDPTFSLMFDGYFEEINFQTPSLINAASYLQALCLAENLRTDVKDLATLLATNNCDIRQSVLYLQFWVRSGGGYLKDKHLVLHGKDETNPADQVINSEKTTDPKIVFSQDDATPQEFPKCDSGCVETLLGLKNILLPSEDLFTFLKQRITTKENWDKLIQLLTEFQLKKVDFIYSNLEFLLPLPVNYLSNQSEASNPIPERTTIVSSKNSSVNTYCYGKSNSGRKSKKTKNKKRLEELDDSDLFDTGLNYSAEFITLPSDSPTPCAEVNEEESKLMNNRNEMKSKTPSNDRRSALVLQCLNSVTEFVEDMSFLDCCVNSTVKEPLEFSKDEGFNWMNGKIKNGLCDEFSIENTDWWSSQSCSEIKAAIEALSFNKCSVSISQNLEASLSTNNTPESDQLEGLTLRMSDTRNSVSFNQSADLSIHKKAQKRLAVIRTVFSRTPLNLGNKQASILEYLPTLRSICRSEKLKEQGKTKRRFLHYLEGIHLEIPRQVINSLSLDFP", "length": 1825, "header": "tr|A0A8V1ADY7-1|A0A8V1ADY7_CHICK Isoform 1 of ATPase family, AAA domain containing 5 OS=Gallus gallus OX=9031 GN=ATAD5 PE=4 SV=1 CANONICAL=A0A8V1ADY7-1" }, "locus": { "chromosome": "18", "start_pos": 7270436, "end_pos": 7255174, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071546.1", "url": "https://www.ensembl.org/id/ENSGALT00010071546.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044236.1", "url": "https://www.ensembl.org/id/ENSGALP00010044236.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADY7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADY7" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADY7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADY7" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADY7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADY7" } ], "pmid": "" }, { "name": "DNA clamp unloader activity", "id": "GO:0061860", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061860", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADY7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADY7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADY7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADY7" } ], "pmid": "" }, { "name": "Elg1 RFC-like complex", "id": "GO:0031391", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031391", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADY7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADY7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "cell population proliferation", "id": "GO:0008283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008283", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADY7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADY7" } ], "pmid": "" }, { "name": "positive regulation of DNA replication", "id": "GO:0045740", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045740", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADY7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADY7" } ], "pmid": "" }, { "name": "negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator", "id": "GO:1902166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902166", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADY7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADY7" } ], "pmid": "" }, { "name": "nuclear DNA replication", "id": "GO:0033260", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033260", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADY7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADY7" } ], "pmid": "" }, { "name": "positive regulation of cell cycle G2/M phase transition", "id": "GO:1902751", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902751", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADY7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADY7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1095, "end_pos": 1097, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1096, "end_pos": 1098, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1152, "end_pos": 1154, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1513, "end_pos": 1515, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1532, "end_pos": 1534, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1572, "end_pos": 1574, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1641, "end_pos": 1643, "annotation": "n_glycosylation_sequon" }, { "start_pos": 166, "end_pos": 168, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1714, "end_pos": 1716, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1739, "end_pos": 1741, "annotation": "n_glycosylation_sequon" }, { "start_pos": 185, "end_pos": 187, "annotation": "n_glycosylation_sequon" }, { "start_pos": 258, "end_pos": 260, "annotation": "n_glycosylation_sequon" }, { "start_pos": 296, "end_pos": 298, "annotation": "n_glycosylation_sequon" }, { "start_pos": 620, "end_pos": 622, "annotation": "n_glycosylation_sequon" }, { "start_pos": 649, "end_pos": 651, "annotation": "n_glycosylation_sequon" }, { 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"n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", 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"mass": { "chemical_mass": 8850.0, "monoisotopic_mass": 8850.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "CaM kinase-like vesicle-associated protein", "type": "recommended", "evidence": [ { "id": "A0A8V1ADY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADY9/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADY9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADY9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADY9", "locus": {} } ], "crossref": [ { "id": "A0A8V1ADY9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1ADY9", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR011009", "url": 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vesicle-associated protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1ADY9-1" }, "locus": { "chromosome": "12", "start_pos": 2737531, "end_pos": 2736714, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066222.1", "url": "https://www.ensembl.org/id/ENSGALT00010066222.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040488.1", "url": "https://www.ensembl.org/id/ENSGALP00010040488.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], 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"MASCQPTRWWSSCWMCWRTRWSSLRATTSCAHSRTLRRTPKSLDTSRGGNRSVRGGVPLCPSVAPPCPFCPPRDFKAFSAAAAEFHPYIPFFATFDPKVARKLTLKLNEIDFYEPFMEEPLTLPAPPHGKEEIAAFVGEHKRATLRKLKPESMYETWEDDIDGIHIVAFAEEDDPDGFEFLETLKEVARDNTDNPELSIIWIDPEDFPLLIPFWEKTFGIDLSRPQIGVVNVTDADSVWLRMADEDDLPDVAELEEWIEDVLEGKSTLRTTTMTTMTTLMTMTALMTTIRATPSPSLRVAIKVPIGQHWAV", "length": 311, "header": "tr|A0A8V1ADZ3-1|A0A8V1ADZ3_CHICK Isoform 1 of Calsequestrin OS=Gallus gallus OX=9031 GN=LOC107050773 PE=3 SV=1 CANONICAL=A0A8V1ADZ3-1" }, "locus": { "chromosome": "25", "start_pos": 79815, "end_pos": 75276, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068954.1", "url": "https://www.ensembl.org/id/ENSGALT00010068954.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042396.1", "url": "https://www.ensembl.org/id/ENSGALP00010042396.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { 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"https://www.ebi.ac.uk/interpro/entry/IPR023410", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036815", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036815", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:427820", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427820", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "AYGEAHE", "url": "https://omabrowser.org/oma/group/AYGEAHE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AE41", "url": "https://www.orthodb.org/?gene=A0A8V1AE41", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AL77", "url": "https://www.orthodb.org/?gene=A0A8V1AL77", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1APG8", "url": "https://www.orthodb.org/?gene=A0A8V1APG8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NMY1", "url": "https://www.orthodb.org/?gene=F1NMY1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR18860", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18860", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00244", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00244", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-2565942", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2565942", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-380259", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-380259", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-380270", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-380270", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-380284", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-380284", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-380320", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-380320", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5620912", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5620912", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5628897", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5628897", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-8854518", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8854518", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9614399", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9614399", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9929491", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9929491", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1AE41", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE41", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AE41-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE41-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AL77", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL77", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AL77-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL77-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1APG8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APG8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1APG8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APG8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NMY1", "url": "https://www.uniprot.org/uniprotkb/F1NMY1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NMY1-1", "url": "https://www.uniprot.org/uniprotkb/F1NMY1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLSGFVTWDEFLISLKLRVCLLVLGCATCHELSSEPPRHPWRRWLEPSGGGKIHGQAWVTELNEPLSNEERNLLSVAYKNVVGARRSSWRVISSIEQKTSADGNEKKIEMVRAYREKIEKELEAVCQDVLSLLDNYLIKNCSETQYESKVFYLKMKGDYYRYLAEVATGEKRATVVESSEKAYSEAHEISKEHMQPTHPIRLGLALNYSVFYYEIQNAPEQACHLAKTAFDDAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDQQDDDGGEGNN", "length": 276, "header": "tr|A0A8V1AE41-1|A0A8V1AE41_CHICK Isoform 1 of Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma OS=Gallus gallus OX=9031 GN=YWHAG PE=1 SV=1 CANONICAL=A0A8V1AE41-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AE41-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE41/entry#A0A8V1AE41-1", "sequence": { "sequence": "MLSGFVTWDEFLISLKLRVCLLVLGCATCHELSSEPPRHPWRRWLEPSGGGKIHGQAWVTELNEPLSNEERNLLSVAYKNVVGARRSSWRVISSIEQKTSADGNEKKIEMVRAYREKIEKELEAVCQDVLSLLDNYLIKNCSETQYESKVFYLKMKGDYYRYLAEVATGEKRATVVESSEKAYSEAHEISKEHMQPTHPIRLGLALNYSVFYYEIQNAPEQACHLAKTAFDDAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDQQDDDGGEGNN", "length": 276, "header": "tr|A0A8V1AE41-1|A0A8V1AE41_CHICK Isoform 1 of Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma OS=Gallus gallus OX=9031 GN=YWHAG PE=1 SV=1 CANONICAL=A0A8V1AE41-1" }, "locus": { "chromosome": "19", "start_pos": 4736292, "end_pos": 4728505, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071591.1", "url": "https://www.ensembl.org/id/ENSGALT00010071591.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044281.1", "url": "https://www.ensembl.org/id/ENSGALP00010044281.1" } ] } }, { "isoform_ac": "A0A8V1AL77-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE41/entry#A0A8V1AL77-1", "sequence": { "sequence": "MQNGDGSEFCDWLSHRSSPMTFCMQKLKVTELNEPLSNEERNLLSVAYKNVVGARRSSWRVISSIEQKTSADGNEKKIEMVRAYREKIEKELEAVCQDVLSLLDNYLIKNCSETQYESKVFYLKMKGDYYRYLAEVATGEKRATVVESSEKAYSEAHEISKEHMQPTHPIRLGLALNYSVFYYEIQNAPEQACHLAKTAFDDAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDQQDDDGGEGNN", "length": 246, "header": "tr|A0A8V1AL77-1|A0A8V1AE41_CHICK Computationally mapped isoform of Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma OS=Gallus gallus OX=9031 GN=YWHAG PE=1 SV=1 CANONICAL=A0A8V1AE41-1" }, "locus": { "chromosome": "19", "start_pos": 4736292, "end_pos": 4731096, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071590.1", "url": "https://www.ensembl.org/id/ENSGALT00010071590.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044280.1", "url": "https://www.ensembl.org/id/ENSGALP00010044280.1" } ] } }, { "isoform_ac": "A0A8V1APG8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE41/entry#A0A8V1APG8-1", "sequence": { "sequence": "MFFFAKGDVAWSQPMGVGGGCAWTYASLGGLKVTELNEPLSNEERNLLSVAYKNVVGARRSSWRVISSIEQKTSADGNEKKIEMVRAYREKIEKELEAVCQDVLSLLDNYLIKNCSETQYESKVFYLKMKGDYYRYLAEVATGEKRATVVESSEKAYSEAHEISKEHMQPTHPIRLGLALNYSVFYYEIQNAPEQACHLAKTAFDDAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDQQDDDGGEGNN", "length": 250, "header": "tr|A0A8V1APG8-1|A0A8V1AE41_CHICK Computationally mapped isoform of Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma OS=Gallus gallus OX=9031 GN=YWHAG PE=1 SV=1 CANONICAL=A0A8V1AE41-1" }, "locus": { "chromosome": "19", "start_pos": 4736292, "end_pos": 4727973, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071592.1", "url": "https://www.ensembl.org/id/ENSGALT00010071592.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044282.1", "url": "https://www.ensembl.org/id/ENSGALP00010044282.1" } ] } }, { "isoform_ac": "F1NMY1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE41/entry#F1NMY1-1", "sequence": { "sequence": "MVDREQLVQKARLAEQAERYDDMAAAMKNVTELNEPLSNEERNLLSVAYKNVVGARRSSWRVISSIEQKTSADGNEKKIEMVRAYREKIEKELEAVCQDVLSLLDNYLIKNCSETQYESKVFYLKMKGDYYRYLAEVATGEKRATVVESSEKAYSEAHEISKEHMQPTHPIRLGLALNYSVFYYEIQNAPEQACHLAKTAFDDAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDQQDDDGGEGNN", "length": 247, "header": "tr|F1NMY1-1|A0A8V1AE41_CHICK Computationally mapped isoform of Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma OS=Gallus gallus OX=9031 GN=YWHAG PE=1 SV=3 CANONICAL=A0A8V1AE41-1" }, "locus": { "chromosome": "19", "start_pos": 4736292, "end_pos": 4720302, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071595.1", "url": "https://www.ensembl.org/id/ENSGALT00010071595.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044285.1", "url": "https://www.ensembl.org/id/ENSGALP00010044285.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:427820", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427820", "resource": "KEGG Pathway" }, { "id": "R-GGA-2565942", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2565942", "resource": "Reactome", "description": "Regulation of PLK1 Activity at G2/M Transition" }, { "id": "R-GGA-380259", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-380259", "resource": "Reactome", "description": "Loss of Nlp from mitotic centrosomes" }, { "id": "R-GGA-380270", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-380270", "resource": "Reactome", "description": "Recruitment of mitotic centrosome proteins and complexes" }, { "id": "R-GGA-380284", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-380284", "resource": "Reactome", "description": "Loss of proteins required for interphase microtubule organization from the centrosome" }, { "id": "R-GGA-380320", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-380320", "resource": "Reactome", "description": "Recruitment of NuMA to mitotic centrosomes" }, { "id": "R-GGA-5620912", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5620912", "resource": "Reactome", "description": "Anchoring of the basal body to the plasma membrane" }, { "id": "R-GGA-5628897", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5628897", "resource": "Reactome", "description": "TP53 Regulates Metabolic Genes" }, { "id": "R-GGA-8854518", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8854518", "resource": "Reactome", "description": "AURKA Activation by TPX2" }, { "id": "R-GGA-9614399", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9614399", "resource": "Reactome", "description": "Regulation of localization of FOXO transcription factors" }, { "id": "R-GGA-9929491", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9929491", "resource": "Reactome", "description": "SPOP-mediated proteasomal degradation of PD-L1(CD274)" } ], "orthologs": [ { "uniprot_canonical_ac": "E7F354-1", "protein_name": "14-3-3 protein gamma-1", "gene_name": "ywhag2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MVDREQLVQKARLAEQAERYDDMAAAMKSVTELNEALSNEERNLLSVAYKNVVGARRSSWRVISSIEQKTSADGNEKKIEMVRAYREKIEKELEAVCQDVLNLLDNFLIKNCSETQHESKVFYLKMKGDYYRYLAEVATGEKRSTVVESSEKSYNEAHEISKEHMQPTHPIRLGLALNYSVFYYEIQNAPEQACHLAKTAFDDAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDQQDDEGGEGNN", "length": 247 }, "evidence": [ { "id": "A0A8V1AE41", "url": "https://omabrowser.org/oma/group/A0A8V1AE41/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F2Z4Z1-1", "protein_name": "Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma", "gene_name": "YWHAG", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVDREQLVQKARLAEQAERYDDMAAAMKNVTELNEPLSNEERNLLSVAYKNVVGARRSSWRVISSIEQKTSADGNEKKIEMVRAYREKIEKELEAVCQDVLSLLDNYLIKNCSETQYESKVFYLKMKGDYYRYLAEVATGEKRATVVESSEKAYSEAHEISKEHMQPTHPIRLGLALNYSVFYYEIQNAPEQACHLAKTAFDDAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDQQDDDGGEGNN", "length": 247 }, "evidence": [ { "id": "A0A8V1AE41", "url": "https://omabrowser.org/oma/group/A0A8V1AE41/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P61981-1", "protein_name": "14-3-3 protein gamma", "gene_name": "YWHAG", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVDREQLVQKARLAEQAERYDDMAAAMKNVTELNEPLSNEERNLLSVAYKNVVGARRSSWRVISSIEQKTSADGNEKKIEMVRAYREKIEKELEAVCQDVLSLLDNYLIKNCSETQYESKVFYLKMKGDYYRYLAEVATGEKRATVVESSEKAYSEAHEISKEHMQPTHPIRLGLALNYSVFYYEIQNAPEQACHLAKTAFDDAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDQQDDDGGEGNN", "length": 247 }, "evidence": [ { "id": "A0A8V1AE41", "url": "https://omabrowser.org/oma/group/A0A8V1AE41/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P61982-1", "protein_name": "14-3-3 protein gamma", "gene_name": "Ywhag", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVDREQLVQKARLAEQAERYDDMAAAMKNVTELNEPLSNEERNLLSVAYKNVVGARRSSWRVISSIEQKTSADGNEKKIEMVRAYREKIEKELEAVCQDVLSLLDNYLIKNCSETQYESKVFYLKMKGDYYRYLAEVATGEKRATVVESSEKAYSEAHEISKEHMQPTHPIRLGLALNYSVFYYEIQNAPEQACHLAKTAFDDAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDQQDDDGGEGNN", "length": 247 }, "evidence": [ { "id": "A0A8V1AE41", "url": "https://omabrowser.org/oma/group/A0A8V1AE41/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P61983-1", "protein_name": "14-3-3 protein gamma", "gene_name": "Ywhag", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVDREQLVQKARLAEQAERYDDMAAAMKNVTELNEPLSNEERNLLSVAYKNVVGARRSSWRVISSIEQKTSADGNEKKIEMVRAYREKIEKELEAVCQDVLSLLDNYLIKNCSETQYESKVFYLKMKGDYYRYLAEVATGEKRATVVESSEKAYSEAHEISKEHMQPTHPIRLGLALNYSVFYYEIQNAPEQACHLAKTAFDDAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDQQDDDGGEGNN", "length": 247 }, "evidence": [ { "id": "A0A8V1AE41", "url": "https://omabrowser.org/oma/group/A0A8V1AE41/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 9, "go_terms": [ { "name": "positive regulation of T cell mediated immune response to tumor cell", "id": "GO:0002842", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002842", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AE41", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE41" } ], "pmid": "" }, { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AE41", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE41" } ], "pmid": "" }, { "name": "regulation of synaptic plasticity", "id": "GO:0048167", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048167", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AE41", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE41" } ], "pmid": "" }, { "name": "regulation of protein localization", "id": "GO:0032880", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032880", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AE41", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE41" } ], "pmid": "" }, { "name": "regulation of neuron differentiation", "id": "GO:0045664", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045664", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AE41", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE41" } ], "pmid": "" }, { "name": "cellular response to glucose starvation", "id": "GO:0042149", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042149", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AE41", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE41" } ], "pmid": "" }, { "name": "intracellular protein localization", "id": "GO:0008104", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008104", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AE41", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE41" } ], "pmid": "" }, { "name": "positive regulation of T cell activation", "id": "GO:0050870", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050870", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AE41", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE41" } ], "pmid": "" }, { "name": "negative regulation of TORC1 signaling", "id": "GO:1904262", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904262", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AE41", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE41" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AE41", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE41" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AE41", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE41" } ], "pmid": "" }, { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AE41", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE41" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AE41", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE41" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "protein domain specific binding", "id": "GO:0019904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019904", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AE41", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE41" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AE41", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE41" } ], "pmid": "" }, { "name": "insulin-like growth factor receptor binding", "id": "GO:0005159", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005159", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AE41", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE41" } ], "pmid": "" }, { "name": "protein kinase C binding", "id": "GO:0005080", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005080", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AE41", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE41" } ], "pmid": "" }, { "name": "phosphorylation-dependent protein binding", "id": "GO:0140031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140031", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AE41", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE41" } ], "pmid": "" }, { "name": "protein sequestering activity", "id": "GO:0140311", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140311", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AE41", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE41" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 140, "end_pos": 142, "annotation": "n_glycosylation_sequon" }, { "start_pos": 207, "end_pos": 209, "annotation": "n_glycosylation_sequon" }, { "start_pos": 258, "end_pos": 260, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AE41", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE41" }, { "id": "SM00101", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00101" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "14-3-3", "eco_id": "ECO_0000259", "start_pos": 46, "end_pos": 276, "start_aa": "Glu", "end_aa": "Asn", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 140, "end_pos": 142 }, { "start_pos": 207, "end_pos": 209 }, { "start_pos": 258, "end_pos": 260 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": 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}, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { 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"A0A8V1AE42-1", "uniprot_ac": "A0A8V1AE42", "uniprot_id": "A0A8V1AE42_CHICK", "mass": { "chemical_mass": 70596.0, "monoisotopic_mass": 70596.0 }, "refseq": { "ac": "XP_004944581", "name": "EF-hand and coiled-coil domain-containing protein 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004944581" }, "gene_names": [ { "name": "EFCC1", "type": "recommended", "evidence": [ { "id": "A0A8V1AE42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE42" } ] }, { "name": "EFCC1", "type": "synonym", "evidence": [ { "id": "XP_004944581", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004944581" } ] } ], "protein_names": [ { "name": "EF-hand and coiled-coil domain containing 1", "type": "synonym", "evidence": [ { "id": "A0A8V1AE42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE42/entry#names_and_taxonomy" } ] }, { "name": "EF-hand and coiled-coil domain-containing protein 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_004944581", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004944581" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052543.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004944581.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004944581", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004944581" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AE42", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE42" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "EFCC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE42", "locus": {} } ], "crossref": [ { "id": "A0A8V1AE42", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AE42", "database": "AlphaFoldDB", "categories": [] }, { "id": "415972", "url": "https://www.ncbi.nlm.nih.gov/gene/415972", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002048", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002048", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031601", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031601", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:415972", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415972", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RCDDKAF", "url": "https://omabrowser.org/oma/group/RCDDKAF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AE42", "url": "https://www.orthodb.org/?gene=A0A8V1AE42", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PF15799", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15799", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004944581", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004944581", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AE42", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE42", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AE42-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE42-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEPPEGWDPYGRPARRTQWLVSALAYHYGLDRGVENEIVVLATGLDQYLQEIFHHLDCAGEGRIPGEDFRTLCQVLGLEEAAEAAADPEECAALWDGLSAELTFRQFHARLCGYFSTKAGSAVPRLPLGRESEHIETQIRLRSPRRRRRDAAGPGSGRRGGEAAERRAAGPCSPECYEEIVALERAEDRIAKLEEENGSLRELVEDMRAALQSSDARCLALQVGLRKSHANHKEEGTCFIGSKRLLTQNHSQTKCLQSVLKEVELIRSSRDGQIEEAIRFNQELERELKSSQEALVSLEDCNRNLKREQAEMRKKVEEARQAVRNSLGKVKELEVKANEVPHLQVYIQQLESELQHYRSEIVKFQLTSRSSPEQKDAAALSDGRCCFSVVQQDRTSPTGRAGISENADEQLFRAVEGQAASDEEEEKWAGEQQPQAACMKEILAKFPCCGSGCDEKKRKKLLTYLETSSVDGYEAAVELEEHISQLSEQLELKGEEVKKLETNMEEMKGSLLTELQQKVEETEMLKMELQMLETERVRLSLVEEKLMDVLQLLQQLRDLNISKRALGKILLSTLESCHDPQHGKAHLFEVLDTLYRQLTACELLQSQPLEKAQSRQSLSNPLVISC", "length": 626, "header": "tr|A0A8V1AE42-1|A0A8V1AE42_CHICK Isoform 1 of EF-hand and coiled-coil domain containing 1 OS=Gallus gallus OX=9031 GN=EFCC1 PE=4 SV=1 CANONICAL=A0A8V1AE42-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AE42-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE42/entry#A0A8V1AE42-1", "sequence": { "sequence": "MEPPEGWDPYGRPARRTQWLVSALAYHYGLDRGVENEIVVLATGLDQYLQEIFHHLDCAGEGRIPGEDFRTLCQVLGLEEAAEAAADPEECAALWDGLSAELTFRQFHARLCGYFSTKAGSAVPRLPLGRESEHIETQIRLRSPRRRRRDAAGPGSGRRGGEAAERRAAGPCSPECYEEIVALERAEDRIAKLEEENGSLRELVEDMRAALQSSDARCLALQVGLRKSHANHKEEGTCFIGSKRLLTQNHSQTKCLQSVLKEVELIRSSRDGQIEEAIRFNQELERELKSSQEALVSLEDCNRNLKREQAEMRKKVEEARQAVRNSLGKVKELEVKANEVPHLQVYIQQLESELQHYRSEIVKFQLTSRSSPEQKDAAALSDGRCCFSVVQQDRTSPTGRAGISENADEQLFRAVEGQAASDEEEEKWAGEQQPQAACMKEILAKFPCCGSGCDEKKRKKLLTYLETSSVDGYEAAVELEEHISQLSEQLELKGEEVKKLETNMEEMKGSLLTELQQKVEETEMLKMELQMLETERVRLSLVEEKLMDVLQLLQQLRDLNISKRALGKILLSTLESCHDPQHGKAHLFEVLDTLYRQLTACELLQSQPLEKAQSRQSLSNPLVISC", "length": 626, "header": "tr|A0A8V1AE42-1|A0A8V1AE42_CHICK Isoform 1 of EF-hand and coiled-coil domain containing 1 OS=Gallus gallus OX=9031 GN=EFCC1 PE=4 SV=1 CANONICAL=A0A8V1AE42-1" }, "locus": { "chromosome": "12", "start_pos": 5373469, "end_pos": 5329052, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067767.1", "url": "https://www.ensembl.org/id/ENSGALT00010067767.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041510.1", "url": "https://www.ensembl.org/id/ENSGALP00010041510.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:415972", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415972", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZRE8-1", "protein_name": "EF-hand and coiled-coil domain containing 1", "gene_name": "Efcc1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MESSAGDPYRRPARRAQWLLSALAHHYGLDRGVENEIVVLATGLDQYLQEVFHHLDCRGAGRLPRADFRALCAVLGLNADGEAAKEDANSTEVAAKNPATGMIAGGDADVREEALLALRADPPELTFRQFHARLCGYFSSRAGSRLPRGALSEHIETQIRLRRPRRRRRPGSPSLHGGAYGERVAHLEEENSSLRELVEDLRAALQSSDARCLALQVGLWKSQSDIPEAAAHELQRAQGALAEAEARARRLQRGQVEVRLRTEEARQAVRRSLHRVRELESLARRVPRLQRQVQRLEAELRRYRSEGPQLLTPPQTSPRPGNKNGEPTARGTRDSDTTSEGVLQSDTSLRSRDTDEEEEQLFRSVEGQAASEEEEEERWQEKPGRPQAHSEVPLMQPSGCVNRCDDQTAETLKASFGHCDGAEHVCTLELEPHVTRLGEQLQTLGCSRETLGRPEEEEEEEEEAELQQMVETEHLRLELQMVETERVRLSLMEEKLVDVLQLLQRLRDLNISKRALGKMLLNALDQNPSQEGTRGTLAILDTLHQALVGCELLQRNPSAPASKAPAHTNPFLVSC", "length": 575 }, "evidence": [ { "id": "A0A8V1AE42", "url": "https://omabrowser.org/oma/group/A0A8V1AE42/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9HA90-1", "protein_name": "EF-hand and coiled-coil domain-containing protein 1", "gene_name": "EFCC1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEPVSTGAEAGMEGAGGDPYRRPARRTQWLLSALAHHYGLDRGVENEIVVLATGLDQYLQEVFHHLDCRGAGRLPRADFRALCAVLGLRAEGATTAGQAAGDGNSRDVTPGDAAAELATDGDSDTDEEARLALRAEPPELTFRQFHARLCGYFGTRAGPRLPRGALSEHIETQIRLRRPRRRRRPPCAPGPDSGPDCERVARLEEENSSLRELVEDLRAALQSSDARCLALQVGLWKSQASTHEMGHGGPEAAVRELRQAQGALAAAEARAGRLRRGQAEVRRRAEEARQVVLRSLHRVRELEALAQQVPGLQRWVRRLEAELQRYRSEDSQLPTPQLANPEPGDKSNEPEDAGTRDPDPTPEGAWQSDSSSGSRALDEVDEQLFRSVEGQAASDEEEVEEERWQEEKKTPAAEAKTLLARLSSCRGRCDDQTAEKLMTYFGHFGGANHAHTLGELEACIAMLVEQLRTQGCGGRTLGTSEEEAELQQKVEENEHLRLELQMVETERVRLSLLEEKLVDVLQLLQRLRDLNISKRALGKILLSTLDAFRDPTHEGRPSPAAILDALHQALAACQLLRRQPSAPASAAAALTNPLLVSC", "length": 598 }, "evidence": [ { "id": "A0A8V1AE42", "url": "https://omabrowser.org/oma/group/A0A8V1AE42/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9JJF6-1", "protein_name": "EF-hand and coiled-coil domain-containing protein 1", "gene_name": "Efcc1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESSAGDPYRRPARRTQWLLSALAHHYGLDRGVENEIVVLATGLDQYLQEVFHHLDCRGAGRLPRADFRALCAVLGLNADGETATEDANSAEAASTNPAAGMIAGGDADVREEARLALRADPPELTFRQFHARLCGYFSSRAGPRLPRGALSEHIETQIRLRRPRRRRRPGSPSLHGGAYGERVAHLEEENSSLRELVEDLRAALQSSDARCLALQVGLWKSQSDIPEAAAHELQRAQGALAEAEARARRLQRGQVEVRLRTEEARQAVRRSLHRVRELEALARRVPCLQRQVQRLEAELRGYRSEGPQLLTPQQASPRPGNRNGEPTAGGTRDSDTTPEGVQRSDSRDTDEEDEQLFRSVEGQAASEEEEEERWQEKPGRPQAHGEVPLVQPSGCVSRCDDQTAETLKASFGHCDGAEHICTLELETHVTRLGEQLQTLGTPEEEAELQQMVEAEHLRLELQMVETERVRLSLLEEKLVDVLQLLQRLRDLNISKRALGKMLLNALDRNPSQEGTCGTLAILDTLHQALVGCELLQRNPSAPASTAPAHTNPFLISC", "length": 558 }, "evidence": [ { "id": "A0A8V1AE42", "url": "https://omabrowser.org/oma/group/A0A8V1AE42/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AE42", 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"sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AE44-1", "uniprot_ac": "A0A8V1AE44", "uniprot_id": "A0A8V1AE44_CHICK", "mass": { "chemical_mass": 60213.0, "monoisotopic_mass": 60213.0 }, "refseq": {}, "gene_names": [ { "name": "LOC112529939", "type": "recommended", "evidence": [ { "id": "A0A8V1AE44", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE44" } ] } ], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "A0A8V1AE44", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE44/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AE44", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE44" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus 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"id": "IPR055406", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055406", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AE44", "url": "https://www.orthodb.org/?gene=A0A8V1AE44", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23120", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23120", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23120:SF42", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23120:SF42", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF21047", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21047", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23227", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23227", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1AE44", "url": 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"UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AE50-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE50-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPFAKANGRLQLWLPRPQCHHGERPPPRREVRFRRVGDRSWTQVMCETGKGEDGEDDPVSCELGGTAAFEVQLRHRTQHWSSHWSDWSTSIFVPEEILESPALSFSLGHLGRNGQRLLQLGWQRARAAQGNVTYTLRAHMPECSCAEEDEVVLGPEETEYNLTLCGAAYEIVLTAANAAGSGPARRLCVPAEQHTELSFRNISSVGSSVMALWEAPTRGFAFCSERQRLPGAPQPGHCVQEEFLARSSHWQTGPLEAPACYRLAVHGRGAEEDWATFALQHRFVGNTSLAASVRINASADAAVLSWEPSPRAACPGALVGYRVCHAAEGDNVTYGEVDASVSQYALRDLKPGTAYRVGIHEVAAGGGGTCSARWHFQTPALGVGTAVWSSNLKYLGISLGLPAAALIYQLSKKRLHGMLFPPLPKPTGSEALRFSASETSQVSCSVHPGMSCEAETSQHCAPSPQQDKPWKSFVEPSEQLSPGELLVMELSPEKEAATSARPHTPELSPKELTEPLQPHCNMELPFAYRQQEVLYPEPVGSGGVPTCDPTAAEEDAGKWGLSQVLAPVVLLKHITPQDQEGVGLLQEKAVP", "length": 591, "header": "tr|A0A8V1AE50-1|A0A8V1AE50_CHICK Isoform 1 of Interleukin 12 receptor subunit beta 1 OS=Gallus gallus OX=9031 GN=IL12RB1 PE=3 SV=1 CANONICAL=A0A8V1AE50-1" }, "isoforms": 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"evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066287.1", "url": "https://www.ensembl.org/id/ENSGALT00010066287.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040553.1", "url": "https://www.ensembl.org/id/ENSGALP00010040553.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AE50", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE50" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 131, "end_pos": 133, "annotation": "n_glycosylation_sequon" }, { "start_pos": 161, "end_pos": 163, "annotation": "n_glycosylation_sequon" }, { "start_pos": 201, "end_pos": 203, "annotation": 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AE70-1", "uniprot_ac": "A0A8V1AE70", "uniprot_id": "A0A8V1AE70_CHICK", "mass": { "chemical_mass": 25615.0, "monoisotopic_mass": 25615.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "A0A8V1AE70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE70/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": 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"UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "GGGGEWGRGGTNAWGGQGEPRSDRWAVGGEQGALGRHHFVAAGDDRGILGAAGSQPKGQDCRCVSESVASKLDQRFPFAVLKRIPGLKYIPGSSAERRATESSKITPLPGTYPTQRYYCSSPPTLPASQMQHLGVQSQRFQDSCTPGFGHALGHVGSQHSYARYSLASSPSQARGASADCCIQSHTGALPGQCCQTGKFSVPQQVCLSGAQAPVDLDLLTGVKQASGDPEASAAPVPAEFSKVQVY", "length": 246, "header": "tr|A0A8V1AE70-1|A0A8V1AE70_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1AE70-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AE70-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE70/entry#A0A8V1AE70-1", "sequence": { "sequence": "GGGGEWGRGGTNAWGGQGEPRSDRWAVGGEQGALGRHHFVAAGDDRGILGAAGSQPKGQDCRCVSESVASKLDQRFPFAVLKRIPGLKYIPGSSAERRATESSKITPLPGTYPTQRYYCSSPPTLPASQMQHLGVQSQRFQDSCTPGFGHALGHVGSQHSYARYSLASSPSQARGASADCCIQSHTGALPGQCCQTGKFSVPQQVCLSGAQAPVDLDLLTGVKQASGDPEASAAPVPAEFSKVQVY", "length": 246, "header": "tr|A0A8V1AE70-1|A0A8V1AE70_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1AE70-1" }, "locus": { "chromosome": "19", "start_pos": 4833224, "end_pos": 4827649, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071621.1", "url": "https://www.ensembl.org/id/ENSGALT00010071621.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044311.1", "url": "https://www.ensembl.org/id/ENSGALP00010044311.1" } ] } }, { "isoform_ac": "A0A8V1AN10-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE70/entry#A0A8V1AN10-1", "sequence": { "sequence": "MVLATVFCLDLPESVASKLDQRFPFAVLKRIPGLKYIPGSSAERRATESSKITPLPGTYPTQRYYCSSPPTLPASQMQHLGVQSQRFQDSCTPGFGHALGHVGSQHSYARYSLASSPSQARGASADCCIQSHTGALPGQCCQTGKFSVPQQVCLSGAQAPVDLDLLTGVKQASGDPEASAAPVPAEFSKVQVY", "length": 193, "header": "tr|A0A8V1AN10-1|A0A8V1AE70_CHICK Computationally mapped isoform of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1AE70-1" }, "locus": { "chromosome": "19", "start_pos": 4830274, "end_pos": 4827649, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071619.1", "url": "https://www.ensembl.org/id/ENSGALT00010071619.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044309.1", "url": "https://www.ensembl.org/id/ENSGALP00010044309.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], 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"table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { 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"total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AE73-1", "uniprot_ac": "A0A8V1AE73", "uniprot_id": "A0A8V1AE73_CHICK", "mass": { "chemical_mass": 53493.0, "monoisotopic_mass": 53493.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "A0A8V1AE73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE73/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AE73", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE73" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE73", "locus": {} } ], "crossref": [ { "id": "A0A8V1AE73", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AE73", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR050938", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050938", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR37456", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR37456", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR37456:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR37456:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AE73", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE73", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AE73-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE73-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAPPSRGPLPPPPPKSLQGPGGHWGALGGIGGVWGDGGLWVQWGLWGRRGGCGVTGGCGVTEGSGIMGGCGVMGGVMGSWGDVGSWGGYGFSGQCGVTGGCGVTGGCGVTVGYGVTGCYGLTGGCGVTTGLWGHCGLWGHGGCGVTVGYGVTGGSQEVVGSLWALGSWGVMGSLWAMGSRGLWGHCVLWGHGGLWGHCGLWGHGGLWSHSGLWDLGGLWGHRGLWGHSELWGHRGLWGHCALWGHGGSQGAVGSWGVMGPLWAMGSRGAVGSLCAVGSGGVMGSLCAVGSRGVMGPLWAMGSRGGHRGLWGHCVLWGHGGLWGHCGLWGHIGLWGHCGLWGHGGLWGHCMLGSPTHVGVTHRYWGHPQMLGAPIDVGVTHRHWDHPQMLGSPTDIGVTHRCWGHPQTLGSPTDIGVPPLDWGSRWARSSRWPLGSPTDVGISQYWGPQMCPGGPTDVGVPPWMLGSPAGVGVSSRRSLRPPAAIGLFTWPGGPHGCGAPHRSQGPPQILGSPRPFWSPQPLGAP", "length": 524, "header": "tr|A0A8V1AE73-1|A0A8V1AE73_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1AE73-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AE73-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE73/entry#A0A8V1AE73-1", "sequence": { "sequence": "MAPPSRGPLPPPPPKSLQGPGGHWGALGGIGGVWGDGGLWVQWGLWGRRGGCGVTGGCGVTEGSGIMGGCGVMGGVMGSWGDVGSWGGYGFSGQCGVTGGCGVTGGCGVTVGYGVTGCYGLTGGCGVTTGLWGHCGLWGHGGCGVTVGYGVTGGSQEVVGSLWALGSWGVMGSLWAMGSRGLWGHCVLWGHGGLWGHCGLWGHGGLWSHSGLWDLGGLWGHRGLWGHSELWGHRGLWGHCALWGHGGSQGAVGSWGVMGPLWAMGSRGAVGSLCAVGSGGVMGSLCAVGSRGVMGPLWAMGSRGGHRGLWGHCVLWGHGGLWGHCGLWGHIGLWGHCGLWGHGGLWGHCMLGSPTHVGVTHRYWGHPQMLGAPIDVGVTHRHWDHPQMLGSPTDIGVTHRCWGHPQTLGSPTDIGVPPLDWGSRWARSSRWPLGSPTDVGISQYWGPQMCPGGPTDVGVPPWMLGSPAGVGVSSRRSLRPPAAIGLFTWPGGPHGCGAPHRSQGPPQILGSPRPFWSPQPLGAP", "length": 524, "header": "tr|A0A8V1AE73-1|A0A8V1AE73_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1AE73-1" }, "locus": { "chromosome": "25", "start_pos": 523208, "end_pos": 520482, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066312.1", "url": "https://www.ensembl.org/id/ENSGALT00010066312.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040578.1", "url": "https://www.ensembl.org/id/ENSGALP00010040578.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 455, "start_aa": "Thr", "end_pos": 455, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr455", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 455 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AE76-1", "uniprot_ac": "A0A8V1AE76", "uniprot_id": "A0A8V1AE76_CHICK", "mass": { "chemical_mass": 38532.0, "monoisotopic_mass": 38532.0 }, "refseq": {}, "gene_names": [ { "name": "SHD", "type": "recommended", "evidence": [ { "id": "A0A8V1AE76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE76" } ] } ], "protein_names": [ { "name": "Src homology 2 domain containing transforming protein D", "type": "synonym", "evidence": [ { "id": "A0A8V1AE76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE76/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AE76", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE76" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SHD", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE76", "locus": { "chromosome": "28", "start_pos": 1822920, "end_pos": 1826267, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028506", "url": "https://www.ensembl.org/id/ENSGALG00010028506" } ] } } ], "crossref": [ { "id": "A0A8V1AE76", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AE76", "database": "AlphaFoldDB", "categories": [] }, { "id": "107055336", "url": "https://www.ncbi.nlm.nih.gov/gene/107055336", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000980", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000980", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036860", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036860", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051846", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051846", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:107055336", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:107055336", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "AKEFRRP", "url": "https://omabrowser.org/oma/group/AKEFRRP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AE76", "url": "https://www.orthodb.org/?gene=A0A8V1AE76", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AIY4", "url": "https://www.orthodb.org/?gene=A0A8V1AIY4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15127", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15127", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15127:SF33", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15127:SF33", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00017", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00017", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1AE76", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE76", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AE76-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE76-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AIY4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIY4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AIY4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIY4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAKWLREYLGRGARRSPPRPPQPDYSGGERRPPGTGSGTASPRHRLVRVGGPGRLEQGPNESEYSEPFEQNAAPEGSNEDPREAAGRPRHGGGQRVRGQRDPRLYDTPCEEWEKVGEGAGGGAARESRLPRDDERPADEYDQPWEWKKDHISRAFAVQFESPERSPSLSRQPPRPPRPPPGTRPLCPPSPGHVDTSLPLEKQAWYHGPIGRAGAETLLALCREGSFLVRDCETSPDDYSLSLRYAVGRPYGAGVARRAKGRPHPYRAHAAPRVPHSAPQEQPRLRAREADADAGAALRVGARGGRLPLRARRCAALHGASAARPRRPAPLPALPRGCAAPLSPTAPGIPPERSH", "length": 354, "header": "tr|A0A8V1AE76-1|A0A8V1AE76_CHICK Isoform 1 of Src homology 2 domain containing transforming protein D OS=Gallus gallus OX=9031 GN=SHD PE=4 SV=1 CANONICAL=A0A8V1AE76-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AE76-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE76/entry#A0A8V1AE76-1", "sequence": { "sequence": "MAKWLREYLGRGARRSPPRPPQPDYSGGERRPPGTGSGTASPRHRLVRVGGPGRLEQGPNESEYSEPFEQNAAPEGSNEDPREAAGRPRHGGGQRVRGQRDPRLYDTPCEEWEKVGEGAGGGAARESRLPRDDERPADEYDQPWEWKKDHISRAFAVQFESPERSPSLSRQPPRPPRPPPGTRPLCPPSPGHVDTSLPLEKQAWYHGPIGRAGAETLLALCREGSFLVRDCETSPDDYSLSLRYAVGRPYGAGVARRAKGRPHPYRAHAAPRVPHSAPQEQPRLRAREADADAGAALRVGARGGRLPLRARRCAALHGASAARPRRPAPLPALPRGCAAPLSPTAPGIPPERSH", "length": 354, "header": "tr|A0A8V1AE76-1|A0A8V1AE76_CHICK Isoform 1 of Src homology 2 domain containing transforming protein D OS=Gallus gallus OX=9031 GN=SHD PE=4 SV=1 CANONICAL=A0A8V1AE76-1" }, "locus": { "chromosome": "28", "start_pos": 1826175, "end_pos": 1823077, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069029.1", "url": "https://www.ensembl.org/id/ENSGALT00010069029.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042471.1", "url": "https://www.ensembl.org/id/ENSGALP00010042471.1" } ] } }, { "isoform_ac": "A0A8V1AIY4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE76/entry#A0A8V1AIY4-1", "sequence": { "sequence": "MAKWLREYLGRGARRSPPRPPQPDYSGGERRPPGTGSGTASPRHRLVRVGGPGRLEQGPNESEYSEPFEQNAAPEGSNEDPREAAGRPRHGGGQRVRGQRDPRLYDTPCEEWEKVGEGAGGGAARESRLPRDDERPADEYDQPWEWKKDHISRAFAVQFESPERSPSLSRQPPRPPRPPPGTRPLCPPSPGHVDTSLPLEKQAWYHGPIGRAGAETLLALCREGSFLVRDCETSPDDYSLSLRSSHGFVHVKLTRTRERHFVLGRAGAAFPSVPDAVRHYTARALPVRGARHLSLLYPVAAQPP", "length": 304, "header": "tr|A0A8V1AIY4-1|A0A8V1AE76_CHICK Computationally mapped isoform of Src homology 2 domain containing transforming protein D OS=Gallus gallus OX=9031 GN=SHD PE=4 SV=1 CANONICAL=A0A8V1AE76-1" }, "locus": { "chromosome": "28", "start_pos": 1826175, "end_pos": 1823118, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069030.1", "url": "https://www.ensembl.org/id/ENSGALT00010069030.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042472.1", "url": "https://www.ensembl.org/id/ENSGALP00010042472.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:107055336", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:107055336", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "E1BE26-1", "protein_name": "SH2 domain-containing adapter protein D", "gene_name": "SHD", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAKWLRDYLSFGGRRPPPQPPTPDYTESDILRAYREQKDLDFEDPYEDADSRLEPDSSGGPGDSKGPGDAKYDSPKHRLIKVEAVDIARAKVLLGSPGEESKVDTEYSDPFDAQPHPPPPDDGYMEPYDAQRVMSELPCRRVQLYDTPYEEQDQELGDGPPSGQKPRQSRLPQEDERPADEYDQPWEWKKDHISKAFAVQFDSPDWERTSGSAKELRRPPPRSPQPAERVDPTLPLEKQPWFHGLLSRADAENLLSLCKEGSYLVRLSESSPQDCSLSLRSSQGFLHLKFARTRENQFVLGQHSGPFPSVPELVLHYSSRPLPVQGAEHLALLYPVVSQTP", "length": 341 }, "evidence": [ { "id": "A0A8V1AE76", "url": "https://omabrowser.org/oma/group/A0A8V1AE76/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1S7M3-1", "protein_name": "SH2 domain-containing adapter protein D", "gene_name": "SHD", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAKWLRDYLSFGGRRPPPQPPTPDYTESDILRAYREQKDLDFEDPYEDADSRLEPDSAGPGDSKGPGDAKYDSPKHRLIKVEAVDMARAKVLLGSACEESEVDAEYSDPFDAQPHPPPPDNGYMEPYDAQRIVSELPCRGVQLYDTPYEEQDQEPGDETPSGRKPRQSRLPQEDERPADEYDQPWEWKKDHISKAFAVQFDSPEWERTSGSAKELRRPPHRSPQPAERVDPALPLEKQPWFHGPLSRADAENLLSLCKEGSYLVRLSETSPQDCSLSLRSSQGFLHLKFARTRENQFVLGQHSGPFPSVPELVLHYSSRPLPVQGAEHLALLYPVVSQSP", "length": 340 }, "evidence": [ { "id": "A0A8V1AE76", "url": "https://omabrowser.org/oma/group/A0A8V1AE76/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "M0R864-1", "protein_name": "SH2 domain-containing adapter protein D", "gene_name": "Shd", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAKWLRDYLNLGSRRPPPQPPTPDYTESDILRAYREQKDLDFEDPYEDSNGRPESEITESSDPKYNSPRHRLIKVEAVNLARAKTLLGSLGEEPEADTEYSDPFDAQPQPPAPNNGYMEPYDARNISSEQPSRAVQLYDTPYEEQDMKPEDGGSSGQSRRPLEDERPADEYDQPWEWKKDHISRAFAVQFHGPDWERTPCSTKEPWRPQPAERVDTALALEKQPWFHGPLSRVEAENLLSLCKEGSYLVRLSETRAQDCILSLRSNQGSMHLKFAKTRENQVVLGQHSGPFPSVPELVLHYSARPLPVQGIEHLALLYPVTSSQSSQGPCTLAARPEKGQGDP", "length": 343 }, "evidence": [ { "id": "A0A8V1AE76", "url": "https://omabrowser.org/oma/group/A0A8V1AE76/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O88834-1", "protein_name": "SH2 domain-containing adapter protein D", "gene_name": "Shd", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAKWLRDYLNLGSRRPPPQPPTPDYTESDILRAYREQKDLDFEDPYEDSNGRAEPEVTGSGDPKYNSPRHRLIKVEAADMARAKALLGSPGEEPEAETEYSDPFDAQPQPPAPNSGYMEPYDARSVSSEQPSRAVQLYDTPYEEQATKPEDGGSSGQSRRPLEDERPADEYDQPWEWKKDHISRAFAVQFDGPDWERTPCSTKEPWRPQPAERVDTALALEKQPWFHGPLSRAEAENLLSLCKEGSYLVRLSETRAQDCILSLRSNQGSMHLKFARTRENQVVLGQHSGPFPSIPELVLHYSARPLPVQGAEHLALLYPVTSSQSSQGPCTLAAKPERGQGDP", "length": 343 }, "evidence": [ { "id": "A0A8V1AE76", "url": "https://omabrowser.org/oma/group/A0A8V1AE76/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96IW2-1", "protein_name": "SH2 domain-containing adapter protein D", "gene_name": "SHD", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAKWLRDYLSFGGRRPPPQPPTPDYTESDILRAYRAQKNLDFEDPYEDAESRLEPDPAGPGDSKNPGDAKYGSPKHRLIKVEAADMARAKALLGGPGEELEADTEYLDPFDAQPHPAPPDDGYMEPYDAQWVMSELPGRGVQLYDTPYEEQDPETADGPPSGQKPRQSRMPQEDERPADEYDQPWEWKKDHISRAFAVQFDSPEWERTPGSAKELRRPPPRSPQPAERVDPALPLEKQPWFHGPLNRADAESLLSLCKEGSYLVRLSETNPQDCSLSLRSSQGFLHLKFARTRENQVVLGQHSGPFPSVPELVLHYSSRPLPVQGAEHLALLYPVVTQTP", "length": 340 }, "evidence": [ { "id": "A0A8V1AE76", "url": "https://omabrowser.org/oma/group/A0A8V1AE76/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "phosphotyrosine residue binding", "id": "GO:0001784", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001784", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AE76", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE76" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 60, "end_pos": 62, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AE76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE76" }, { "id": "PS50001", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50001" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SH2", "eco_id": "ECO_0000259", "start_pos": 204, "end_pos": 275, "start_aa": "Trp", "end_aa": "His", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 60, "end_pos": 62 } ] 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"protein_names": [ { "name": "BolA family member 1", "type": "synonym", "evidence": [ { "id": "A0A8V1AE96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE96/entry#names_and_taxonomy" } ] }, { "name": "bolA-like protein 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015128795", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015128795" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052556.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015128795.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015128795", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015128795" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AE96", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE96" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC107049580", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE96", "locus": {} } ], "crossref": [ { "id": "107049580", "url": "https://www.ncbi.nlm.nih.gov/gene/107049580", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002634", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002634", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036065", "url": 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"categories": [ "Protein Classification" ] }, { "id": "PF01722", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01722", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015128795", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015128795", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AE96", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE96", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AE96-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE96-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPPPTLSALPSGPVARSILSKLTAALQPTHLHLEDHSPRHGAPPGSETHFGLLVVSGRFEGLSPIERHRLVHAVLGAELRGPLHALSIVARTPQQWERDPNIPQPPPCMGGSKRDKRQAEGDAAASQ", "length": 127, "header": "tr|A0A8V1AE96-1|A0A8V1AE96_CHICK Isoform 1 of BolA family member 1 OS=Gallus gallus OX=9031 GN=LOC107049580 PE=3 SV=1 CANONICAL=A0A8V1AE96-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AE96-1", "url": 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"common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9D8S9-1", "protein_name": "BolA-like protein 1", "gene_name": "Bola1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSARSAQCMVSMATRSCVSRGSAGSAAAGPVEAAIRAKLEQALSPEVLELRNESGGHAVPAGSETHFRVAVVSSRFEGMSPLQRHRLVHEALSEELAGPVHALAIQAKTPAQWRENPQLDISPPCLGGSKKTRGTS", "length": 137 }, "evidence": [ { "id": "A0A8V1AE96", "url": "https://omabrowser.org/oma/group/A0A8V1AE96/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VC53-1", "protein_name": "BolA-like protein DDB_G0274169", "gene_name": "CG13621", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MLNFTLRRLTGVSIRNLNQLTPTISSLGQILPRATMSQEAGQYPPIESAMRKALNTELKPVYLEVINESPQHNVPKRSESHFRVFVVSEKFNDLTLIKRHRLVNDTVKNALKEAGFEFMHALSIEAKTPKQWEPEQEPEKSPPCLGGHGK", "length": 150 }, "evidence": [ { "id": "A0A8V1AE96", "url": "https://omabrowser.org/oma/group/A0A8V1AE96/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9Y3E2-1", "protein_name": "BolA-like protein 1", "gene_name": "BOLA1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLSGRLVLGLVSMAGRVCLCQGSAGSGAIGPVEAAIRTKLEEALSPEVLELRNESGGHAVPPGSETHFRVAVVSSRFEGLSPLQRHRLVHAALAEELGGPVHALAIQARTPAQWRENSQLDTSPPCLGGNKKTLGTP", "length": 137 }, "evidence": [ { "id": "A0A8V1AE96", "url": "https://omabrowser.org/oma/group/A0A8V1AE96/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AE96", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE96" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], 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This record is derived from a genomic sequence (NC_052549.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004946409.1. 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"Protein Classification" ] }, { "id": "IPR039135", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039135", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:422109", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422109", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WHVPRYH", "url": "https://omabrowser.org/oma/group/WHVPRYH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AEB6", "url": "https://www.orthodb.org/?gene=A0A8V1AEB6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ALD8", "url": "https://www.orthodb.org/?gene=A0A8V1ALD8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AN40", "url": "https://www.orthodb.org/?gene=A0A8V1AN40", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13256", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13256", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13256:SF16", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13256:SF16", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13302", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13302", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004946409", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004946409", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "69607", "url": "https://www.rhea-db.org/rhea/69607", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1AEB6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEB6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AEB6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEB6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALD8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALD8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALD8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALD8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AN40", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN40", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AN40-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN40-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRINQNTALRGDKVTLVPYSSAHVPRYHEWMQSEELQRLTASEPLSLEQEYEMQRSWRDDADKCTFIVLDTERWSEQACGDEDCMVGDVNIFLTDPEDPTLGEIEIMIAEPSYRGRGFGKEATLMMMSYGVTELGITKFEAKIGQENEASICMFKKLNFKEVSVNSVFQEVTLRLDVTDQERQWLLEQTKHVKKKSYTEEKLPAGGLETDR", "length": 211, "header": "tr|A0A8V1AEB6-1|A0A8V1AEB6_CHICK Isoform 1 of Alpha/beta-tubulin-N-acetyltransferase 9 OS=Gallus gallus OX=9031 GN=NAT9 PE=3 SV=1 CANONICAL=A0A8V1AEB6-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AEB6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEB6/entry#A0A8V1AEB6-1", "sequence": { "sequence": "MRINQNTALRGDKVTLVPYSSAHVPRYHEWMQSEELQRLTASEPLSLEQEYEMQRSWRDDADKCTFIVLDTERWSEQACGDEDCMVGDVNIFLTDPEDPTLGEIEIMIAEPSYRGRGFGKEATLMMMSYGVTELGITKFEAKIGQENEASICMFKKLNFKEVSVNSVFQEVTLRLDVTDQERQWLLEQTKHVKKKSYTEEKLPAGGLETDR", "length": 211, "header": "tr|A0A8V1AEB6-1|A0A8V1AEB6_CHICK Isoform 1 of Alpha/beta-tubulin-N-acetyltransferase 9 OS=Gallus gallus OX=9031 GN=NAT9 PE=3 SV=1 CANONICAL=A0A8V1AEB6-1" }, "locus": { "chromosome": "18", "start_pos": 11086290, "end_pos": 11083520, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071671.1", "url": "https://www.ensembl.org/id/ENSGALT00010071671.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044361.1", "url": "https://www.ensembl.org/id/ENSGALP00010044361.1" } ] } }, { "isoform_ac": "A0A8V1ALD8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEB6/entry#A0A8V1ALD8-1", "sequence": { "sequence": "MRINQNTALRGDKVTLVPYSSAHVPRYHEWMQSEELQRLTASEPLSLEQEYEMQRSWRDDADKCTFIVLDTERWSEQACGDEDCMVGDVNIFLTDPEDPTLEPSYRGRGFGKEATLMMMSYGVTELGITKFEAKIGQENEASICMFKKLNFKEVSVNSVFQEVTLRLDVTDQERQWLLEQTKHVKKKSYTEEKLPAGGLETDR", "length": 203, "header": "tr|A0A8V1ALD8-1|A0A8V1AEB6_CHICK Computationally mapped isoform of Alpha/beta-tubulin-N-acetyltransferase 9 OS=Gallus gallus OX=9031 GN=NAT9 PE=3 SV=1 CANONICAL=A0A8V1AEB6-1" }, "locus": { "chromosome": "18", "start_pos": 11086290, "end_pos": 11083520, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071670.1", "url": "https://www.ensembl.org/id/ENSGALT00010071670.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044360.1", "url": "https://www.ensembl.org/id/ENSGALP00010044360.1" } ] } }, { "isoform_ac": "A0A8V1AN40-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEB6/entry#A0A8V1AN40-1", "sequence": { "sequence": "MVLSRQSCRISRYHEWMQSEELQRLTASEPLSLEQEYEMQRSWRDDADKCTFIVLDTERWSEQACGDEDCMVGDVNIFLTDPEDPTLGEIEIMIAEPSYRGRGFGKEATLMMMSYGVTELGITKFEAKIGQENEASICMFKKLNFKEVSVNSVFQEVTLRLDVTDQERQWLLEQTKHVKKKSYTEEKLPAGGLETDR", "length": 197, "header": "tr|A0A8V1AN40-1|A0A8V1AEB6_CHICK Computationally mapped isoform of Alpha/beta-tubulin-N-acetyltransferase 9 OS=Gallus gallus OX=9031 GN=NAT9 PE=3 SV=1 CANONICAL=A0A8V1AEB6-1" }, "locus": { "chromosome": "18", "start_pos": 11085842, "end_pos": 11083520, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071669.1", "url": "https://www.ensembl.org/id/ENSGALT00010071669.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044359.1", "url": "https://www.ensembl.org/id/ENSGALP00010044359.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:422109", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422109", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A9J7JY19-1", "protein_name": "Alpha/beta-tubulin-N-acetyltransferase 9", "gene_name": "Nat9", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MRLNQNTVLLGKKVALVPYTSEHVPRQNSSPHPLQRGSPVTQAGLQFLILLPPPPRYHEWMKSEELRHLTASELLTLEQEYEMQCSWCEDEDKCTFIVLDAEKWQAQPRPPEESCMVGDVNLFLTDLEDPTLGEIEVMIAEPSCRGQGLGTEASLLMMSYDSGGVTKLGLTKFEAKIGQENEPSIRMFQKLHFKQVAVSNVFQEVTLRLAVTEAERQWLLEQTSHVEEKPYRVELAEPVAATLCEQTWSHPLPRPDSCMGESCTVSSGCSRPS", "length": 273 }, "evidence": [ { "id": "A0A8V1AEB6", "url": "https://omabrowser.org/oma/group/A0A8V1AEB6/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q3UG98-1", "protein_name": "Alpha/beta-tubulin-N-acetyltransferase 9", "gene_name": "Nat9", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKLNQNTMLVGKKVVLVPYTSEHVPRYHEWMKSEELRHLTASEQLTLQQEYEMQCSWCEDEDKCTFIVLDAEKWQAQPRPPEESCMVGDVNLFLTDLEDPTLGEIEVMIAEPSYRRQGLGTEASLLIMSYGVTKLGLTKFEAKIGQENEPSIRMFQKLHFKQVAMSNVFQEVTLRLAVSEPERKWILEQTSHMEERPYRTRKAEPVTATLSEQKSWNCPLPRPDGCMGDTSAVSSVCARLS", "length": 241 }, "evidence": [ { "id": "A0A8V1AEB6", "url": "https://omabrowser.org/oma/group/A0A8V1AEB6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q86II5-1", "protein_name": "N-acetyltransferase 9-like protein", "gene_name": "nat9", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKINSNTIIIGKKVILVPYKKKHVEKYWKWMQSEEIREQTASEELTIEEEFENQESWFKDDHKITFIILDKDLLLENEKDSNGYSNENDIKSMIGDVNIFFNQYEDEGTAELEVMIAEPTSRRKGLAREAISIIMGYGIEHLSTITKKYIVKIGESNQPSIQMFKSMNFKQIGSVNVFKEILLEFENGENNINLLNLKNNDNYKSLIFKNWE", "length": 212 }, "evidence": [ { "id": "A0A8V1AEB6", "url": "https://omabrowser.org/oma/group/A0A8V1AEB6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9BTE0-1", "protein_name": "Alpha/beta-tubulin-N-acetyltransferase 9", "gene_name": "NAT9", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRLNQNTLLLGKKVVLVPYTSEHVPSRYHEWMKSEELQRLTASEPLTLEQEYAMQCSWQEDADKCTFIVLDAEKWQAQPGATEESCMVGDVNLFLTDLEDLTLGEIEVMIAEPSCRGKGLGTEAVLAMLSYGVTTLGLTKFEAKIGQGNEPSIRMFQKLHFEQVATSSVFQEVTLRLTVSESEHQWLLEQTSHVEEKPYRDGSAEPC", "length": 207 }, "evidence": [ { "id": "A0A8V1AEB6", "url": "https://omabrowser.org/oma/group/A0A8V1AEB6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9V9V9-1", "protein_name": "Alpha/beta-tubulin-N-acetyltransferase 9", "gene_name": "Mnat9", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MHLNENTKILGHRVILVPYEARHVPKYHEWMSNETLRELTASEELTLEEEHEMQRSWREDSDKLTFIVLDAETYSRDQDEIAAMVGDTNLFLHQDPDSQIPTAEAEIMIAEPYARGKGFGREAMLLMLKYAQSQPQLKLDKFEVKIDMDNAASLHLFKSFMFVETRRVEIFHEVTLERPITPDWINWLDQQVDLRMQCYQ", "length": 200 }, "evidence": [ { "id": "A0A8V1AEB6", "url": "https://omabrowser.org/oma/group/A0A8V1AEB6/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEB6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEB6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of mitotic spindle assembly", "id": "GO:1901673", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901673", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEB6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEB6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "tubulin N-terminal-methionine acetyltransferase activity", "id": "GO:0120519", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120519", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEB6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEB6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "69607", "name": "", "equation": "N-terminal L-methionyl-[tubulin] + acetyl-CoA = N-terminal N(alpha)-acetyl-L-methionyl-[tubulin] + CoA + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V1AEB6-1" ], "evidence": [ { "id": "69607", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/69607" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A8V1AEB6", "gene_name": "NAT9", "activity": [ { "ec_number": "2.3.1.308", "activity": "N-terminal L-methionyl-[tubulin] + acetyl-CoA = N-terminal N(alpha)-acetyl-L-methionyl-[tubulin] + CoA + H(+).", "evidence": [ { "id": "A0A8V1AEB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEB6" } ] }, { "ec_number": "2.3.1.308", "activity": "", "evidence": [ { "id": "A0A8V1AEB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEB6" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AEB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEB6" }, { "id": "PF13302", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13302" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "N-acetyltransferase", "eco_id": "ECO_0000259", "start_pos": 14, "end_pos": 160, "start_aa": "Val", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.3.1.308", "ec_name": "N-terminal L-methionyl-[tubulin] + acetyl-CoA = N-terminal N(alpha)-acetyl-L-methionyl-[tubulin] + CoA + H(+).", "evidence": [ { "id": "2.3.1.308", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.308" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AED5-1", "uniprot_ac": "A0A8V1AED5", "uniprot_id": "A0A8V1AED5_CHICK", "mass": { "chemical_mass": 12264.0, "monoisotopic_mass": 12264.0 }, "refseq": { "ac": "NP_001264905", "name": "scale keratin-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264905" }, "gene_names": [ { "name": "LOC100859756", "type": "recommended", "evidence": [ { "id": "A0A8V1AED5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AED5" } ] }, { "name": "LOC100859756", "type": "synonym", "evidence": [ { "id": "NP_001264905", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264905" } ] } ], "protein_names": [ { "name": "Keratin", "type": "recommended", "evidence": [ { "id": "A0A8V1AED5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AED5/entry#names_and_taxonomy" } ] }, { "name": "scale keratin-like", "type": "synonym", "evidence": [ { "id": "NP_001264905", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264905" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMN02738215, SAMN02738216 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000349.1. On Dec 1, 2021 this sequence version replaced NP_001264905.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001264905", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264905" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AED5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AED5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC100859756", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AED5", "locus": {} } ], "crossref": [ { "id": "A0A8V1AED5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AED5", "database": "AlphaFoldDB", "categories": [] }, { "id": "100859756", "url": "https://www.ncbi.nlm.nih.gov/gene/100859756", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003461", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003461", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:100859756", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100859756", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NEPCVTH", "url": "https://omabrowser.org/oma/group/NEPCVTH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AED5", "url": "https://www.orthodb.org/?gene=A0A8V1AED5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31203", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31203", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31203:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31203:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02422", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02422", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001264905", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264905", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AED5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AED5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AED5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AED5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSCSDLCPPKTSVAVPQPIAESCNELCARQCPDSTAFIQPPPVVVTFPGPILSSFPQQAVVGSSGAPAFGGSLGLGGLYGAGATQGSGGLCTFGRPYVSPACSPCPLPRYSRKLWDNCGPC", "length": 121, "header": "tr|A0A8V1AED5-1|A0A8V1AED5_CHICK Isoform 1 of Keratin OS=Gallus gallus OX=9031 GN=LOC100859756 PE=3 SV=1 CANONICAL=A0A8V1AED5-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AED5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AED5/entry#A0A8V1AED5-1", "sequence": { "sequence": "MSCSDLCPPKTSVAVPQPIAESCNELCARQCPDSTAFIQPPPVVVTFPGPILSSFPQQAVVGSSGAPAFGGSLGLGGLYGAGATQGSGGLCTFGRPYVSPACSPCPLPRYSRKLWDNCGPC", "length": 121, "header": "tr|A0A8V1AED5-1|A0A8V1AED5_CHICK Isoform 1 of Keratin OS=Gallus gallus OX=9031 GN=LOC100859756 PE=3 SV=1 CANONICAL=A0A8V1AED5-1" }, "locus": { "chromosome": "25", "start_pos": 1439078, "end_pos": 1438716, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069079.1", "url": "https://www.ensembl.org/id/ENSGALT00010069079.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042521.1", "url": "https://www.ensembl.org/id/ENSGALP00010042521.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:100859756", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100859756", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "structural constituent of cytoskeleton", "id": "GO:0005200", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005200", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AED5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AED5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "intermediate filament", "id": "GO:0005882", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005882", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AED5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AED5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AEE3-1", "uniprot_ac": "A0A8V1AEE3", "uniprot_id": "A0A8V1AEE3_CHICK", "mass": { "chemical_mass": 37954.0, "monoisotopic_mass": 37954.0 }, "refseq": { "ac": "NP_989804", "name": "opticin precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989804" }, "gene_names": [ { "name": "OPTC", "type": "recommended", "evidence": [ { "id": "A0A8V1AEE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEE3" } ] }, { "name": "OPTC", "type": "synonym", "evidence": [ { "id": "NP_989804", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989804" } ] } ], "protein_names": [ { "name": "Opticin", "type": "synonym", "evidence": [ { "id": "A0A8V1AEE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEE3/entry#names_and_taxonomy" } ] }, { "name": "opticin precursor", "type": "synonym", "evidence": [ { "id": "NP_989804", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989804" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: HAEK01109952.1, HAEL01000596.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992393 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000356.1. On Sep 23, 2021 this sequence version replaced NP_989804.1.", "evidence": [ { "database": "RefSeq", "id": "NP_989804", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989804" } ] }, { "annotation": "The chicken homologue of opticin (cOptc), a member of the small leucine-rich repeat protein (SLRP) family, was isolated. cOptc is expressed in the brain and the neural tube from stage 9 onward.", "evidence": [ { "database": "RefSeq", "id": "NP_989804", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989804" }, { "database": "PubMed", "id": "15053984", "url": "https://glygen.org/publication/PubMed/15053984" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEE3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEE3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "OPTC", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEE3", "locus": { "chromosome": "26", "start_pos": 5221467, "end_pos": 5218089, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027379", "url": "https://www.ensembl.org/id/ENSGALG00010027379" } ] } } ], "crossref": [ { "id": "A0A8V1AEE3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AEE3", "database": "AlphaFoldDB", "categories": [] }, { "id": "395130", "url": "https://www.ncbi.nlm.nih.gov/gene/395130", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000372", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000372", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003591", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003591", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043547", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043547", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:395130", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395130", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "EEHKYTR", "url": "https://omabrowser.org/oma/group/EEHKYTR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AEE3", "url": "https://www.orthodb.org/?gene=A0A8V1AEE3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46269", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46269", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46269:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46269:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00560", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00560", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13855", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13855", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-1474228", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1474228", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_989804", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989804", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AEE3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEE3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AEE3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEE3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MALGHRMQTLAWVGIASLCLGAAWAVPAKKERKKVEKLKPDLVLYENLDLDNYDVTLDNYGDIMDLNNYEELYDYGDLAPKIEVGTLAPRPKDRESLPELATAAPTPKLQPPDTTNPIRPAPPGPGTAQGVPSCLPCLCIRTSVYCDDTDLEHIPPLPPDTTYLYARFNRISAIRAGDFMGLKKLKRIDLTSNSISWADVDAFRFLPSLQELILPENRLTALPELPRSIVRLDARLNRIPSAGLRPEAFQDLTQLQFLHLSDNQLDYIPAPLPESLRSLHLQNNNIQTMHEDTFCNSQDQSHVRRALEDIRLDGNPINLSLFPNAYFCLPRLPTGHFL", "length": 338, "header": "tr|A0A8V1AEE3-1|A0A8V1AEE3_CHICK Isoform 1 of Opticin OS=Gallus gallus OX=9031 GN=OPTC PE=3 SV=1 CANONICAL=A0A8V1AEE3-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AEE3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEE3/entry#A0A8V1AEE3-1", "sequence": { "sequence": "MALGHRMQTLAWVGIASLCLGAAWAVPAKKERKKVEKLKPDLVLYENLDLDNYDVTLDNYGDIMDLNNYEELYDYGDLAPKIEVGTLAPRPKDRESLPELATAAPTPKLQPPDTTNPIRPAPPGPGTAQGVPSCLPCLCIRTSVYCDDTDLEHIPPLPPDTTYLYARFNRISAIRAGDFMGLKKLKRIDLTSNSISWADVDAFRFLPSLQELILPENRLTALPELPRSIVRLDARLNRIPSAGLRPEAFQDLTQLQFLHLSDNQLDYIPAPLPESLRSLHLQNNNIQTMHEDTFCNSQDQSHVRRALEDIRLDGNPINLSLFPNAYFCLPRLPTGHFL", "length": 338, "header": "tr|A0A8V1AEE3-1|A0A8V1AEE3_CHICK Isoform 1 of Opticin OS=Gallus gallus OX=9031 GN=OPTC PE=3 SV=1 CANONICAL=A0A8V1AEE3-1" }, "locus": { "chromosome": "26", "start_pos": 5221261, "end_pos": 5218602, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066383.1", "url": "https://www.ensembl.org/id/ENSGALT00010066383.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040649.1", "url": "https://www.ensembl.org/id/ENSGALP00010040649.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The expression pattern of opticin during chicken embryogenesis.", "journal": "Gene expression patterns : GEP", "date": "2004-05", "authors": "Frolova Elena I, Fokina Valentina M, Beebe David C", "evidence": [ { "database": "RefSeq", "id": "NP_989804", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989804" } ], "reference": [ { "type": "PubMed", "id": "15053984", "url": "https://glygen.org/publication/PubMed/15053984" } ] } ], "pathway": [ { "id": "gga:395130", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395130", "resource": "KEGG Pathway" }, { "id": "R-GGA-1474228", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1474228", "resource": "Reactome", "description": "Degradation of the extracellular matrix" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A096MK02-1", "protein_name": "Opticin", "gene_name": "Optc", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGNLIRHMDPWANYLSSPWPINEGVSSCPLVWQAVIIPIRVFVSLEAAGPDGTKTSKRMYVEWIQPFPLLPFPQNLMKFLTFLSLLTLVLQEAGTASLLGEREREEKSPEEADTYASLHVGNYSLSLEDYSEVIDLSSYEELADYGDQIPEAKTSSPTLPTRTSPTSPVVPRTLPSRLTMAGPTTTGLLNSQSSHGLPTCLVCVCLGSSVYCDDANLENIPPLPQMTTYLYARFNHISHIQAGDFKGMTKLRRIDLSSNSISSIHNDALRLLPALQDLILPENQLAALPVLPSGLEFLDVRLNRLQSSGIQPEAFVTLEKLQFLYLADNLLDSIPGPLPLSLRSLHLQNNKIEAMESDTFCDTTEHRHERRRQLEDIRLDGNPINLSLFPEAYFCLPRLPVGRFT", "length": 405 }, "evidence": [ { "id": "A0A8V1AEE3", "url": "https://omabrowser.org/oma/group/A0A8V1AEE3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P58874-1", "protein_name": "Opticin", "gene_name": "OPTC", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MKLLALLSLLILMLQEARTASLSEEREGDPYAILHLGDYVLSLDNYDEVIDPSNYDELIDYGDQLPQVKGTSLASLTRTRFTQSTEAARTLPSNPTTARPPTLGLLAAPANHGLPTCLICVCLGSSVYCDDADLENIPPLPQTTAYLYARFNRISHIRAGDFKGLTKLKRIDLSGNSISSIDDKALRLLPALRDLILPENKLVALPTLPTSIEVLDVRMNRLQSSGIQPEAFRALEKLQFLYLADNLLDAIPPSLPLSLRSLHLQNNMIETMQRDAFCDAEEHRHTRRPLEDIRLDGNPINLSLFPSAYFCLPRLPTGRFV", "length": 321 }, "evidence": [ { "id": "A0A8V1AEE3", "url": "https://omabrowser.org/oma/group/A0A8V1AEE3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q920A0-1", "protein_name": "Opticin", "gene_name": "Optc", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKFLAFLSLLSLVLQKAETASLLGEREREEQSPEEGDTYASLYVGNHTLSIEDYNEVIDLSNYEELADYGDQIPEAKISNLTLPTRTSPTSTVAQKTLSPNLTMAVPTTTGLLNSQSSHGLPTCLVCVCLGSSVYCDDADLENIPPLPQMTTYLYARFNHISHIQAGDFKGLTKLRRIDLSGNSISSIHNDALRLLPALQDLILPENQLAALPVLPSGIEFLDVRLNRLQSSGIQPEAFVALKKLQFLYLANNMLDSIPGPLPLSLRSLHLQNNMIETMESDTFCDTGEHRHERRQLEDIRLDGNPINLSLFPEAYFCLPRLPVGHFT", 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"GO:0031012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031012", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEE3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEE3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "collagen fibril organization", "id": "GO:0030199", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030199", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEE3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEE3" } ], "pmid": "" }, { "name": "bone development", "id": "GO:0060348", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060348", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEE3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEE3" } ], "pmid": "" }, { "name": "articular cartilage development", "id": "GO:0061975", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061975", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEE3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEE3" } ], 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Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. 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"total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AEG7-1", "uniprot_ac": "A0A8V1AEG7", "uniprot_id": "A0A8V1AEG7_CHICK", "mass": { "chemical_mass": 75375.0, "monoisotopic_mass": 75375.0 }, "refseq": { "ac": "XP_418271", "name": "protein fem-1 homolog A", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418271" }, "gene_names": [ { "name": "FEM1A", "type": "recommended", "evidence": [ { "id": "A0A8V1AEG7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEG7" } ] }, { "name": "FEM1A", "type": "synonym", "evidence": [ { "id": "XP_418271", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418271" } ] } ], "protein_names": [ { "name": "Fem-1 homolog A", "type": "synonym", "evidence": [ { "id": "A0A8V1AEG7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEG7/entry#names_and_taxonomy" } ] }, { "name": "protein fem-1 homolog A", "type": "synonym", "evidence": [ { "id": "XP_418271", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418271" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052559.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Dec 16, 2011 this sequence version replaced XP_418271.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_418271", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418271" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEG7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEG7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FEM1A", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEG7", "locus": { "chromosome": "28", "start_pos": 5296122, "end_pos": 5319645, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028538", "url": "https://www.ensembl.org/id/ENSGALG00010028538" } ] } } ], "crossref": [ { "id": "420157", "url": "https://www.ncbi.nlm.nih.gov/gene/420157", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:420157", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420157", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "EQSSGHP", "url": "https://omabrowser.org/oma/group/EQSSGHP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AEG7", "url": "https://www.orthodb.org/?gene=A0A8V1AEG7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24173", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24173", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24173:SF12", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24173:SF12", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00023", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00023", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12796", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12796", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-8951664", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8951664", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_418271", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418271", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AEG7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEG7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AEG7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEG7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDLRTAVYNAARDGKLKLLQKLLGSRSREELEALTAGPGGGDGPGGGSTPLLIAARHGHLEVVEYLLDHCGARVEEGGSVNFDGETIEGAPPLWAASAAGHLGVVRSLLDHGASVNQTTLTNSTPLRAACFDGHLEIVRYLVGERGADLEVANRHGHTCLMISCYKGHREIARYLLEKGADVNRRSVKGNTALHDCAESGSLEILQLLLRSKARMEKDGYGMTPLLAASVTGHTNIVEYLIQGGLQQEEEDVAENQNETCALGGSHQRCCSAGQKTHEGCDKEQHERCCASASSQDGQQVPNVFCTREAAVEALELLGATFVDKKRDLLGAHKYWRRAMELRYEGGQYLPKPEPRQLVLAYDYSREVSSLEELEALITDPDEMRMQALLIRERILGPSHPDTSYYIRYRGAVYADSGNFERCINLWKYALDMQQGNLEPLSPMTASSFLSFAELFSYVLQDRSKGTLATQLGFCDLMGVLSKGVREVERALMHGKDPVVDSAQFTKTLAIILHLVFLLEKVECTPEQEHQKRQTIYRLLKCSPRAKNGFTPLHMAVDKDTTTVGRYPVGKFPSLHVVNLLLECGADPDSRDYDNNTPLHVAARNNCPLIMSALMEAGAHMDATNAFKQTAYELLDEKLLTKSMMQPFNYITLQCLAARALDKHKIPYKGFIPEELEAFIELH", "length": 682, "header": "tr|A0A8V1AEG7-1|A0A8V1AEG7_CHICK Isoform 1 of Fem-1 homolog A OS=Gallus gallus OX=9031 GN=FEM1A PE=3 SV=1 CANONICAL=A0A8V1AEG7-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AEG7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEG7/entry#A0A8V1AEG7-1", "sequence": { "sequence": "MDLRTAVYNAARDGKLKLLQKLLGSRSREELEALTAGPGGGDGPGGGSTPLLIAARHGHLEVVEYLLDHCGARVEEGGSVNFDGETIEGAPPLWAASAAGHLGVVRSLLDHGASVNQTTLTNSTPLRAACFDGHLEIVRYLVGERGADLEVANRHGHTCLMISCYKGHREIARYLLEKGADVNRRSVKGNTALHDCAESGSLEILQLLLRSKARMEKDGYGMTPLLAASVTGHTNIVEYLIQGGLQQEEEDVAENQNETCALGGSHQRCCSAGQKTHEGCDKEQHERCCASASSQDGQQVPNVFCTREAAVEALELLGATFVDKKRDLLGAHKYWRRAMELRYEGGQYLPKPEPRQLVLAYDYSREVSSLEELEALITDPDEMRMQALLIRERILGPSHPDTSYYIRYRGAVYADSGNFERCINLWKYALDMQQGNLEPLSPMTASSFLSFAELFSYVLQDRSKGTLATQLGFCDLMGVLSKGVREVERALMHGKDPVVDSAQFTKTLAIILHLVFLLEKVECTPEQEHQKRQTIYRLLKCSPRAKNGFTPLHMAVDKDTTTVGRYPVGKFPSLHVVNLLLECGADPDSRDYDNNTPLHVAARNNCPLIMSALMEAGAHMDATNAFKQTAYELLDEKLLTKSMMQPFNYITLQCLAARALDKHKIPYKGFIPEELEAFIELH", "length": 682, "header": "tr|A0A8V1AEG7-1|A0A8V1AEG7_CHICK Isoform 1 of Fem-1 homolog A OS=Gallus gallus OX=9031 GN=FEM1A PE=3 SV=1 CANONICAL=A0A8V1AEG7-1" }, "locus": { "chromosome": "28", "start_pos": 5314786, "end_pos": 5312741, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069104.1", "url": "https://www.ensembl.org/id/ENSGALT00010069104.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042546.1", "url": "https://www.ensembl.org/id/ENSGALP00010042546.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:420157", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420157", "resource": "KEGG Pathway" }, { "id": "R-GGA-8951664", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8951664", "resource": "Reactome", "description": "Neddylation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287A0D5-1", "protein_name": "Fem-1 homolog A", "gene_name": "FEM1A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDLHTAVYNAARDGKLQLLQKLLSGRSREELEELTGEVASGGTPLLIAARYGHLDVVEYLVDRCGASVEAGGSVHFDGETIEGAPPLWAASAAGHLDVVRSLLRRGASVNRTTRTNSTPLRAACFDGHLEVVRYLVGEHQADLEVANRHGHTCLMISCYKGHREIARYLLEQGAQVNRRSAKGNTALHDCAESGSLEILQLLLGCNARMERDGYGMTPLLAASVTGHTNIVEYLIQEQPAGEETRPGLSREGPTASPACVQPQSPRCCSASPEEPLSGESSESCCPTSREAAVEALELLGATYVDKKRDLLGALKHWRRAMELRHQGGAYLPKPEPPQLVLAYDYSREVNTAEELEALITDPDEMRMQALLIRERILGPSHPDTSYYIRYRGAVYADSGNFERCIRLWKYALDMQQNNLEPLSPMTASSFLSFAELFSYVLQDRSAKGSLGTQIGFADLMGVLCKGVREVERALQLPKEPGDSAQFTKALAIILHLLYLLEKVECTPDQEHLKHQTVYRLLKCAPRGKNGFTPLHMAVDAETTNVGRYPVGRFPSLQVVKVLLDCGADPDSRDFDNNTPLHIAAQNNCPGIMNALIEAGAHMDATNAFKKTAYELLDEKLLAKSTIQPFNYVTLQCLAARALDKNKIPYKGFIPEELEAFIELH", "length": 664 }, "evidence": [ { "id": "A0A8V1AEG7", "url": "https://omabrowser.org/oma/group/A0A8V1AEG7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q29RM5-1", "protein_name": "Protein fem-1 homolog A", "gene_name": "FEM1A", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MDLHTAVYNAARDGKLQLLQKLLSGRSREELEELTGEVASGGTPLLIAARYGHLDVVEYLVDRCGASVEAGGSVHFDGEIIEGAPPLWAASAAGHLDVVRSLLRRGASVNRTTRTNSTPLRAACFDGHLEVVRYLVGEHQADLEVANRHGHTCLMISCYKGHREIARYLLEQGAQVNRRSAKGNTALHDCAESGSLEILQLLLGCNARMERDGYGMTPLLAASVTGHTNIVEYLIQEQPAGDEQAQPGLARVQPQGARSSPEEPPSGESYESCCPTSREAAVEALELLGATYVDKKRDLLGALKHWRRAMELRHQGGEYLPKPEPPQLVLAYDYSREVNTTEELEALITDPDEMRMQALLIRERILGPSHPDTSYYIRYRGAVYADSGNFERCIRLWKYALDMQQNNLEPLSPMTASSFLSFAELFSYVLQDRSAKGSLGTPIGFADLMGVLCKGVREVERALQLPKEPGDSAQFTKALAIILHLLYLLEKVECTPDQEHLKHQTVYRLLKCAPRGKNGFTPLHMAVDAETTNVGRYPVGRFPSLQVVKVLLDCGADPDSRDFDNNTPLHIAAQNNCPGIMNALIEAGAHMDATNAFKKTAYELLDEKLLAKSTIQPFNYVTLQCLAARALDKNKIPYKGFIPEELEAFIELH", "length": 653 }, "evidence": [ { "id": "A0A8V1AEG7", "url": "https://omabrowser.org/oma/group/A0A8V1AEG7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q4V890-1", "protein_name": "Protein fem-1 homolog A", "gene_name": "Fem1a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDLHTAVYNAAHDGKLLLLQKLLAGRGREEIEELLGEVAGGGTPLLIAARRGHLDVVEYLVDNCGASVEASGSVHFDGETIEGAPPLWAASAAGHLAVVRSLLRRGASVNRTTRTNSTPLRAACFDGHLDVVRYLVGEHKADLEVANRHGHTCLMISCYKGHREIARYLLERGAQVNRRSAKGNTALHDCAESGSLEILQLLLGCHARMERDGYGMTPLLAASVTGHTNIVEYLIQEQPGHGQLSGTELPGEGSSQMAGNHCSTPEEAEPYESCCPTSREAAVEALELLGATYVDKKRDLLGALKHWRRAMELRHQGGDYLPKPEPQQLVLAYDYSREVSTPQELEALITDPDEMRMQALLIRERILGPSHPDTSYYIRYRGAVYADSGNFERCIRLWKYALDMQQNNLEPLSPMTASSFLSFAELFSYVLQDRSAKGNLGMQLGFADLMGVLSKGVREVERALQLPKEPGDSAQFTKAIAIILHLLYLLEKVECTPSQEHLKHQTVYRLLKCAPRGKNGFTPLHMAVDKETTNVGRYRVGIFPSLQVVKVLLDCGADPDSRDFDNNTPLHVAAQNNCPAIMDALIEAGAHMDATNAFKKTAYELLDSKLLAKSTMQPFNYVTLQCLAARALDRNKVPYKGFIPEELEAFIQLH", "length": 654 }, "evidence": [ { "id": "A0A8V1AEG7", "url": "https://omabrowser.org/oma/group/A0A8V1AEG7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9BSK4-1", "protein_name": "Protein fem-1 homolog A", "gene_name": "FEM1A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDLRTAVYNAARDGKLQLLQKLLSGRSREELDELTGEVAGGGTPLLIAARYGHLDVVEYLVDRCGASVEAGGSVHFDGETIEGAPPLWAASAAGHLDVVRSLLRRGASVNRTTRTNSTPLRAACFDGHLEVVRYLVGEHQADLEVANRHGHTCLMISCYKGHREIARYLLEQGAQVNRRSAKGNTALHDCAESGSLEILQLLLGCKARMERDGYGMTPLLAASVTGHTNIVEYLIQEQPGQEQVAGGEAQPGLPQEDPSTSQGCAQPQGAPCCSSSPEEPLNGESYESCCPTSREAAVEALELLGATYVDKKRDLLGALKHWRRAMELRHQGGEYLPKPEPPQLVLAYDYSREVNTTEELEALITDPDEMRMQALLIRERILGPSHPDTSYYIRYRGAVYADSGNFERCIRLWKYALDMQQSNLEPLSPMTASSFLSFAELFSYVLQDRAAKGSLGTQIGFADLMGVLTKGVREVERALQLPREPGDSAQFTKALAIILHLLYLLEKVECTPSQEHLKHQTVYRLLKCAPRGKNGFTPLHMAVDKDTTNVGRYPVGRFPSLHVVKVLLDCGADPDSRDFDNNTPLHIAAQNNCPAIMNALIEAGAHMDATNAFKKTAYELLDEKLLARGTMQPFNYVTLQCLAARALDKNKIPYKGFIPEDLEAFIELH", "length": 669 }, "evidence": [ { "id": "A0A8V1AEG7", "url": "https://omabrowser.org/oma/group/A0A8V1AEG7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9Z2G1-1", "protein_name": "Protein fem-1 homolog A-A", "gene_name": "Fem1aa", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDLHTAVYNAAHDGKLPLLQKLLAGRGREELEELLGEVAGGGTPLLIAARRGHLDVVEYLVDHCGASVEASGSVHFDGETIEGAPPLWAASAAGHLAVVRSLLRRGASVNRTTRTNSTPLRAACFDGHLDVVRYLVGEHKADLEVANRHGHTCLMISCYKGHREIARYLLERGAQVNRRSAKGNTALHDCAESGSLEILQLLLGCHARMERDGYGMTPLLAASVTGHTNIVEYLIQEQPGHEQLSGTELPGEGSSQVAGNHCSTPEEAEPYESCCPTSREAAVEALELLGATYVDKKRDLLGALKHWRRAMELRHQGGGYLPKPEPQQLVLAYDYSREVTTPQELEALITDPDEMRMQALLIRERILGPSHPDTSYYIRYRGAVYADSGNFERCIRLWKYALDMQQNNLEPLSPMTASSFLSFAELFSYVLQDRSAKGNLGMQLGFADLMGVLSKGVREVERALQLPKEPGDSAQFTKAIAIILHLLYLLEKVECTPSQEHLKHQTVYRLLKCAPRGKNGFTPLHMAVDKETTNVGRYRVGVFPSLQVVKVLLDCGADPDSRDFDNNTPLHIAAQNNCPAIMDALIEAGAHMDATNAFKKTAYELLDSKLLAKSTVQPFNYVTLQCLAARALDRNKVPYKGFIPEELEAFIQLH", "length": 654 }, "evidence": [ { "id": "A0A8V1AEG7", "url": "https://omabrowser.org/oma/group/A0A8V1AEG7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "EP4 subtype prostaglandin E2 receptor binding", "id": "GO:0031867", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031867", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEG7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEG7" } ], "pmid": "" }, { "name": "ubiquitin-like ligase-substrate adaptor activity", "id": "GO:1990756", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990756", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEG7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEG7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEG7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEG7" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { 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"evidence": [ { "id": "XP_015148356", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015148356" } ] } ], "protein_names": [ { "name": "Metabotropic glutamate receptor 2", "type": "recommended", "evidence": [ { "id": "A0A8V1AEI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEI2/entry#names_and_taxonomy" } ] }, { "name": "metabotropic glutamate receptor 2", "type": "synonym", "evidence": [ { "id": "XP_015148356", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015148356" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052543.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015148356.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015148356", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015148356" } ] }, { "annotation": "Dimeric G protein-coupled receptor which is activated by the excitatory neurotransmitter L-glutamate. Plays critical roles in modulating synaptic transmission and neuronal excitability. Upon activation by glutamate, inhibits presynaptic calcium channels, reducing further glutamate release and dampening excitatory signaling. Mechanistically, ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. May mediate suppression of neurotransmission or may be involved in synaptogenesis or synaptic stabilization.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEI2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEI2#function" }, { "database": "UniProtKB", "id": "ARBA00057394", "url": "https://www.uniprot.org/uniprotkb/ARBA00057394#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEI2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEI2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "GRM2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEI2", "locus": { "chromosome": "12", "start_pos": 3095912, "end_pos": 3087390, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027396", "url": "https://www.ensembl.org/id/ENSGALG00010027396" } ] } } ], "crossref": [ { "id": "A0A8V1AEI2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AEI2", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15447", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15447", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "427575", "url": "https://www.ncbi.nlm.nih.gov/gene/427575", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000162", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000162", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000337", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000337", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001458", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001458", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001828", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001828", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011500", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011500", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017978", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017978", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028082", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028082", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038550", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038550", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050726", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050726", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:427575", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427575", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HEKGNPT", "url": "https://omabrowser.org/oma/group/HEKGNPT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AEI2", "url": "https://www.orthodb.org/?gene=A0A8V1AEI2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24060", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24060", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00003", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00003", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01094", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01094", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07562", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07562", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-418594", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-418594", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-420499", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-420499", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015148356", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015148356", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AEI2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEI2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AEI2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEI2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGSVGPRPAPEHPMAVPIAAWLWLMHLAPCLAAGHGSTHGKKEISTEGDLVIGGLFPVHEKGVGGEDCGKINEHRGIQRLEAMLFALDEINKDPSILPGVRLGAHILDTCSKDTYALEQSLDFVRASLTRVDGSEHICPDGSYAVHDDIPMAITGVIGGSYSDVSIQVANLLRLFQIPQISYASTSAKLSDKSRYDYFARTVPPDFYQAKAMSEILRFFNWTYVSTVASEGDYGETGIEAFEQEARMRNICIATSEKVGRSMNKKTYDGVVRALLQKPNARVVVLFTRSEDARELLAAAHRANVSFVWVASDGWGALESVVAGSEAAAEGAITIELAAYPIQEFAAYFLNLHPYNNSRNPWFREFWEQKFKCSLHTQDCSRYSLKTGKFEPESKITFVVNAVYAMAHSLHNMHRALCPNTTKLCDSMKPVNGKRFYKDFMLNVNFDAPFRPADTESVVRFDRYGDGIGRYNIFNYHRMDGRYRYQKVGYWAEGLILNTSLIPWAETSIPVSQCSDPCKKNEIKSMQPGDICCWICIPCQPYEYLLDEFTCMDCGLGYWPNETLNGCYELPQEYIRWKDVWAIGPVTISCLGFISTLFVFGVFMKNNDTPIVKASGRELCYILLTGVLMCYSMTFIFIAKPSTEVCTLRRLGLGTSFAVCYSALLTKTNRIARIFSGVKEGVQRPRFISPTSQVVICMALISCQLIIVIIWLLVEAPGTGKETEPDKRYIVTLKCNNRDSNMLISLTYNVLLIVLCTVYAFKTRKCPENFNEAKFIGFTMYTTCIIWLAFLPIFYVTSSDYRVQTTTMCISVSLSGTVVLGCLFTPKLHIILFQPQKNVASHRVGTTRFSMAAASSSQSHGSASQYVPTVCNGREAVDSTTSSL", "length": 883, "header": "tr|A0A8V1AEI2-1|A0A8V1AEI2_CHICK Isoform 1 of Metabotropic glutamate receptor 2 OS=Gallus gallus OX=9031 GN=GRM2 PE=3 SV=1 CANONICAL=A0A8V1AEI2-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AEI2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEI2/entry#A0A8V1AEI2-1", "sequence": { "sequence": "MGSVGPRPAPEHPMAVPIAAWLWLMHLAPCLAAGHGSTHGKKEISTEGDLVIGGLFPVHEKGVGGEDCGKINEHRGIQRLEAMLFALDEINKDPSILPGVRLGAHILDTCSKDTYALEQSLDFVRASLTRVDGSEHICPDGSYAVHDDIPMAITGVIGGSYSDVSIQVANLLRLFQIPQISYASTSAKLSDKSRYDYFARTVPPDFYQAKAMSEILRFFNWTYVSTVASEGDYGETGIEAFEQEARMRNICIATSEKVGRSMNKKTYDGVVRALLQKPNARVVVLFTRSEDARELLAAAHRANVSFVWVASDGWGALESVVAGSEAAAEGAITIELAAYPIQEFAAYFLNLHPYNNSRNPWFREFWEQKFKCSLHTQDCSRYSLKTGKFEPESKITFVVNAVYAMAHSLHNMHRALCPNTTKLCDSMKPVNGKRFYKDFMLNVNFDAPFRPADTESVVRFDRYGDGIGRYNIFNYHRMDGRYRYQKVGYWAEGLILNTSLIPWAETSIPVSQCSDPCKKNEIKSMQPGDICCWICIPCQPYEYLLDEFTCMDCGLGYWPNETLNGCYELPQEYIRWKDVWAIGPVTISCLGFISTLFVFGVFMKNNDTPIVKASGRELCYILLTGVLMCYSMTFIFIAKPSTEVCTLRRLGLGTSFAVCYSALLTKTNRIARIFSGVKEGVQRPRFISPTSQVVICMALISCQLIIVIIWLLVEAPGTGKETEPDKRYIVTLKCNNRDSNMLISLTYNVLLIVLCTVYAFKTRKCPENFNEAKFIGFTMYTTCIIWLAFLPIFYVTSSDYRVQTTTMCISVSLSGTVVLGCLFTPKLHIILFQPQKNVASHRVGTTRFSMAAASSSQSHGSASQYVPTVCNGREAVDSTTSSL", "length": 883, "header": "tr|A0A8V1AEI2-1|A0A8V1AEI2_CHICK Isoform 1 of Metabotropic glutamate receptor 2 OS=Gallus gallus OX=9031 GN=GRM2 PE=3 SV=1 CANONICAL=A0A8V1AEI2-1" }, "locus": { "chromosome": "12", "start_pos": 3095247, "end_pos": 3089740, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066424.1", "url": "https://www.ensembl.org/id/ENSGALT00010066424.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040690.1", "url": "https://www.ensembl.org/id/ENSGALP00010040690.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:427575", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427575", "resource": "KEGG Pathway" }, { "id": "R-GGA-418594", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-418594", "resource": "Reactome", "description": "G alpha (i) signalling events" }, { "id": "R-GGA-420499", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-420499", "resource": "Reactome", "description": "Class C/3 (Metabotropic glutamate/pheromone receptors)" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2MSH2-1", "protein_name": "Metabotropic glutamate receptor 2", "gene_name": "Grm2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MGSLLGFLALLLLQGAVAEGPAKKVLTLEGDLVLGGLFPVHQKGGPTEECGPVNEHRGIQRLEAMLFALDRINRDPHLLPGVRLGAHILDSCSKDTHALEQALDFVRASLSRGADGSRHICPDGSYATHSDAPTAITGVIGGSYSDVSIQVANLLRLFQIPQISYASTSAKLSDKSRYDYFARTVPPDFFQAKAMAEILRFFNWTYVSTVASEGDYGETGIEAFELEARARNICVATSEKVGRAMSRAAFEGVVRALLQKPSARVAVLFTRSEDARELLAATQRLNASFTWVASDGWGALESVVAGSEGAAEGAITIELASYPISDFASYFQSLDPWNNSRNPWFREFWEERFHCSFRQRNCAAHSLRSVPFEQESKIMFVVNAVYAMAHALHNMHRALCPNTTHLCDAMRPVNGRRLYKDFVLNVKFDAPFRPADTHNEVRFDRFGDGIGRYNIFTYLRAGSGRYRYQKVGYWAEGLTLDTSLIPWASPSAGPLPASRCSEPCLQNEVKSVQPGEVCCWLCIPCQPYEYRLDEFTCADCGLGYWPNASLTGCFELPQEYIRWGDAWAVGPVTIACLGALATLFVLGVFVRHNATPVVKASGRELCYILLGGVFLCYCMTFIFIAKPSTAVCTLRRLGLGTAFSVCYSALLTKTNRIARIFGGAREGAQRPRFISPASQVAICLALISGQLLIVAAWLVVEAPGIGKETAPERREVVTLRCNHRDASMLGSLAYNVLLIALCTLYAFKTRKCPENFNEAKFIGFTMYTTCIIWLAFLPIFYVTSSDYRVQTTTMCVSVSLSGSVVLGCLFAPKLHIILFQPQKNVVSHRTPTSRFGSAAPRASANLGQGSGSQFVPTVCNGREVVDSTTSSL", "length": 872 }, "evidence": [ { "id": "A0A8V1AEI2", "url": "https://omabrowser.org/oma/group/A0A8V1AEI2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8M2BDP3-1", "protein_name": "Metabotropic glutamate receptor 2", "gene_name": "grm2a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MHRSLRTMAQRSAHFRGHGPSWPLHLTLLLLLLARTPQALAIPGYNTDTSKKEIVMDGDLVIGGLFPVHHKGEGAQDCGRINTQRGIQRLEAMLLALDKINQDDQILPGVTLGAHILDTCSKDTYALEQSLEFVRASLTKVDDSEYTCPDGSYAIHDDVPLAISGVIGGSYSDVSIQVANLLRLFQIPQISYASTSAKLSDKSRYDYFARTVPPDFYQAKAMAEILRFFNWTYVSTVASEGDYGETGIDAFQQEARALQICIATSAKVSRSMDQYSYDGVIRSLLQKSNAKVVILFTRSEDARELLVAAKRMNVSFIWVASDGWGAQEVVVRGSESVADGAFTIELASYTIPEFAAYFTNLNPYNNTRNPWFREFWENKFQCSLHDITCGKHSLRDGKFEQESKIMFVVNAVYAMANALHHMRQALCANSTKLCSAMKPVNGKRLYKDYILKTKFDAPFRPADTDNIIHFDAYGDSLGRYNIFHYHKENDEYVYRKVGYWAQDLTLNTTLIPWESQAVPTSQCSDPCRKNEIKSMQPGDVCCWICIPCQPYQYLLDEFTCADCSFGQWPLDNLTGCYDLPEEYIHWEDAWAIGPVSIACLGMLCTLFVIGLFLKNNETPVVKASGRELSYILLLGVLLCYFMTFIYISKPSAVVCTLRRLGLGTSFAVCYSALLTKTNRIARIFNGVKDGAQRPRFISPASQVAICAALISCQLLVVVVWLLVEAPGVRKEVSPERRDVVTLKCNSKDSSMLMSLTYNCVLIILCTFYAFKTRKCPENFNEAKFIGFTMYTTCIIWLAFQPIFYVTASDYRVQTTTMCISVSLSGSVVLGCLFAPKIHIILFQPQKNVTTLRVATTRFSVTTGPGSSFSQASASNIVPTVCNGREVVDSTTSSL", "length": 894 }, "evidence": [ { "id": "A0A8V1AEI2", "url": "https://omabrowser.org/oma/group/A0A8V1AEI2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E1BAB4-1", "protein_name": "Metabotropic glutamate receptor 2", "gene_name": "GRM2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGSLLGLLALLLLWGAVAEGPAKKVLTLEGDLVLGGLFPVHQKGGPAEECGPVNEHRGIQRLEAMLFALDRINRDPSLLPGVRLGAHILDSCSKDTHALEQALDFVRASLSRGADGSRHICPDGSYATHGDAPTAITGVIGGSYSDVSIQVANLLRLFQIPQISYASTSAKLSDKSRYDYFARTVPPDFFQAKAMAEILRFFNWTYVSTVASEGDYGETGIEAFELEARARNICVATSEKVGRAMSRAAFEGVVRALLQKPSARVAVLFTRSEDARELLAATQRLNASFTWVASDGWGALESVVAGSEGAAEGAITIELASYPISDFASYFQSLDPWNNSRNPWFREFWEQRFRCSFRQQDCAAHSLRAVPFEQESKIMFVVNAVYAMAHALHNMHRALCPNTTRLCDAMQPVNGRRLYKDFVLNVKFDAPFRPADTHSEVRFDRFGDGIGRYNIFTYLRAGGGRYRYQKVGYWAEGLTLDTSLIPWASPSAGPLPASRCSEPCLQNEVKSVQPGEVCCWLCIPCQPYEYRLDEFTCADCGLGYWPNASLTGCFELPQEYIRWGDAWAVGPVTIACLGALATLFVLGVFVRHNATPVVKASGRELCYILLGGVFLCYCMTFVFIAKPSTAVCTLRRLGLGTAFSVCYSALLTKTNRIARIFGGAREGAQRPRFISPASQVAICLALISGQLLIVATWLVVEAPGTGKETAPERREVVTLRCNHRDASMLGSLAYNVLLIALCTLYAFKTRKCPENFNEAKFIGFTMYTTCIIWLAFLPIFYVTSSDYRVQTTTMCVSVSLSGSVVLGCLFAPKLHIILFQPQKNVVSHRTPTSRFGSAAARASSSLGQGSGSQFVPTVCNGREVVDSTTSSL", "length": 872 }, "evidence": [ { "id": "A0A8V1AEI2", "url": "https://omabrowser.org/oma/group/A0A8V1AEI2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1SIZ5-1", "protein_name": "Metabotropic glutamate receptor 2", "gene_name": "GRM2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGSLLGLLALLLLWGAVAEGPAKKVLTLEGDLVLGGLFPVHQKGSLAEECGPVNEHRGIQRLEAMLFALDRINRDPSLLPGVRLGAHILDSCSKDTHALEQALDFVRASLSRGADGSRHICPDGSYATHGDAPTAITGVIGGSYSDVSIQVANLLRLFQIPQISYASTSAKLSDKSRYDYFARTVPPDFFQAKAMAEILRFFNWTYVSTVASEGDYGETGIEAFELEARARNICVATSEKVGRAMSRAAFEGVVRSLLQKPSARVAVLFTRSEDARELLAATQRLNASFTWVASDGWGALESVVAGSEGAAEGAITIELASYPISDFASYFRSLDPWNNSRNPWFREFWEQRFRCSFRQRDCASHSLKAVPFEQESKIMFVVNAVYAMAHALHNMHRALCPNTTHLCDAMRPVNGRRLYKDFVLNVKFDAPFRPADTHSEVRFDRFGDGIGRYNIFTYLRAGSGRYRYQKVGYWAEGLTLDTSLIPWASPSAGPLPASRCSEPCLQNEVKSVQPGEVCCWLCIPCQPYEYRLDEFTCADCGLGYWPNASLTGCFELPQEYIHWGDAWALGPVTIACLGALATLFVLGVFVRHNATPVVKASGRELCYILLGGVFLCYCMTFVFIAKPSTAVCTLRRLGLGTAFSVCYSALLTKTNRIARIFGGAREGAQRPRFISPASQVAICLALISGQLLIVATWLVVEAPGTGKETAPERREVVTLRCNHRDASMLGSLAYNVLLIALCTLYAFKTRKCPENFNEAKFIGFTMYTTCIIWLAFLPIFYVTSSDYRVQTTTMCVSVSLSGSVVLGCLFAPKLHIILFQPQKNVVSHRAPTSRFGSAAARASSSLGQGSGSQFVPTVCNGREVVDSTTSSL", "length": 872 }, "evidence": [ { "id": "A0A8V1AEI2", "url": "https://omabrowser.org/oma/group/A0A8V1AEI2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P31421-1", "protein_name": "Metabotropic glutamate receptor 2", "gene_name": "Grm2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MESLLGFLALLLLWGAVAEGPAKKVLTLEGDLVLGGLFPVHQKGGPAEECGPVNEHRGIQRLEAMLFALDRINRDPHLLPGVRLGAHILDSCSKDTHALEQALDFVRASLSRGADGSRHICPDGSYATHSDAPTAVTGVIGGSYSDVSIQVANLLRLFQIPQISYASTSAKLSDKSRYDYFARTVPPDFFQAKAMAEILRFFNWTYVSTVASEGDYGETGIEAFELEARARNICVATSEKVGRAMSRAAFEGVVRALLQKPSARVAVLFTRSEDARELLAATQRLNASFTWVASDGWGALESVVAGSERAAEGAITIELASYPISDFASYFQSLDPWNNSRNPWFREFWEERFHCSFRQRDCAAHSLRAVPFEQESKIMFVVNAVYAMAHALHNMHRALCPNTTHLCDAMRPVNGRRLYKDFVLNVKFDAPFRPADTDDEVRFDRFGDGIGRYNIFTYLRAGSGRYRYQKVGYWAEGLTLDTSFIPWASPSAGPLPASRCSEPCLQNEVKSVQPGEVCCWLCIPCQPYEYRLDEFTCADCGLGYWPNASLTGCFELPQEYIRWGDAWAVGPVTIACLGALATLFVLGVFVRHNATPVVKASGRELCYILLGGVFLCYCMTFVFIAKPSTAVCTLRRLGLGTAFSVCYSALLTKTNRIARIFGGAREGAQRPRFISPASQVAICLALISGQLLIVAAWLVVEAPGTGKETAPERREVVTLRCNHRDASMLGSLAYNVLLIALCTLYAFKTRKCPENFNEAKFIGFTMYTTCIIWLAFLPIFYVTSSDYRVQTTTMCVSVSLSGSVVLGCLFAPKLHIILFQPQKNVVSHRAPTSRFGSAAPRASANLGQGSGSQFVPTVCNGREVVDSTTSSL", "length": 872 }, "evidence": [ { "id": "A0A8V1AEI2", "url": "https://omabrowser.org/oma/group/A0A8V1AEI2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q14416-1", "protein_name": "Metabotropic glutamate receptor 2", "gene_name": "GRM2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGSLLALLALLLLWGAVAEGPAKKVLTLEGDLVLGGLFPVHQKGGPAEDCGPVNEHRGIQRLEAMLFALDRINRDPHLLPGVRLGAHILDSCSKDTHALEQALDFVRASLSRGADGSRHICPDGSYATHGDAPTAITGVIGGSYSDVSIQVANLLRLFQIPQISYASTSAKLSDKSRYDYFARTVPPDFFQAKAMAEILRFFNWTYVSTVASEGDYGETGIEAFELEARARNICVATSEKVGRAMSRAAFEGVVRALLQKPSARVAVLFTRSEDARELLAASQRLNASFTWVASDGWGALESVVAGSEGAAEGAITIELASYPISDFASYFQSLDPWNNSRNPWFREFWEQRFRCSFRQRDCAAHSLRAVPFEQESKIMFVVNAVYAMAHALHNMHRALCPNTTRLCDAMRPVNGRRLYKDFVLNVKFDAPFRPADTHNEVRFDRFGDGIGRYNIFTYLRAGSGRYRYQKVGYWAEGLTLDTSLIPWASPSAGPLPASRCSEPCLQNEVKSVQPGEVCCWLCIPCQPYEYRLDEFTCADCGLGYWPNASLTGCFELPQEYIRWGDAWAVGPVTIACLGALATLFVLGVFVRHNATPVVKASGRELCYILLGGVFLCYCMTFIFIAKPSTAVCTLRRLGLGTAFSVCYSALLTKTNRIARIFGGAREGAQRPRFISPASQVAICLALISGQLLIVVAWLVVEAPGTGKETAPERREVVTLRCNHRDASMLGSLAYNVLLIALCTLYAFKTRKCPENFNEAKFIGFTMYTTCIIWLAFLPIFYVTSSDYRVQTTTMCVSVSLSGSVVLGCLFAPKLHIILFQPQKNVVSHRAPTSRFGSAAARASSSLGQGSGSQFVPTVCNGREVVDSTTSSL", "length": 872 }, "evidence": [ { "id": "A0A8V1AEI2", "url": "https://omabrowser.org/oma/group/A0A8V1AEI2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q14BI2-1", "protein_name": "Metabotropic glutamate receptor 2", "gene_name": "Grm2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESLLRFLALLLLRGAVAEGPAKKVLTLEGDLVLGGLFPVHQKGGPAEECGPVNEHRGIQRLEAMLFALDRINRDPHLLPGVRLGAHILDSCSKDTHALEQALDFVRASLSRGADGSRHICPDGSYATLSDAPTAITGVIGGSYSDVSIQVANLLRLFQIPQISYASTSAKLSDKSRYDYFARTVPPDFFQAKAMAEILRFFNWTYVSTVASEGDYGETGIEAFELEARARNICVATSEKVGRAMSRAAFEGVVRALLQKPSARVAVLFTRSEDARELLAATQRLNASFTWVASDGWGALESVVAGSERAAEGAITIELASYPISDFASYFQNLDPWNNSRNPWFREFWEERFRCSFRQRDCAAHSLRAVPFEQESKIMFVVNAVYAMAHALHNMHRALCPNTTRLCDAMRPVNGRRLYKDFVLNVKFDAPFRPADTDDEVRFDRFGDGIGRYNIFTYLRAGNGRYRYQKVGYWAEGLTLDTSIIPWASPSAGTLPASRCSEPCLQNEVKSVQPGEVCCWLCIPCQPYEYRLDEFTCADCGLGYWPNASLTGCFELPQEYIRWGDAWAVGPVTIACLGALATLFVLGVFVRHNATPVVKASGRELCYILLGGVFLCYCMTFIFIAKPSTAVCTLRRLGLGTAFSVCYSALLTKTNRIARIFGGAREGAQRPRFISPASQVAICLALISGQLLIVAAWLVVEAPGIGKETAPERREVVTLRCNHRDASMLGSLAYNVLLIALCTLYAFKTRKCPENFNEAKFIGFTMYTTCIIWLAFLPIFYVTSSDYRVQTTTMCVSVSLSGSVVLGCLFAPKLHIILFQPQKNVVSHRAPTSRFGSAAPRASANLGQGSGSQLVPTVCNGREVVDSTTSSL", "length": 872 }, "evidence": [ { "id": "A0A8V1AEI2", "url": "https://omabrowser.org/oma/group/A0A8V1AEI2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEI2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEI2" } ], "pmid": "" }, { "name": "dendrite", "id": "GO:0030425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEI2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEI2" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEI2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEI2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "regulation of synaptic transmission, glutamatergic", "id": "GO:0051966", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051966", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEI2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEI2" } ], "pmid": "" }, { "name": "G protein-coupled glutamate receptor signaling pathway", "id": "GO:0007216", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007216", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEI2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEI2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "group II metabotropic glutamate receptor activity", "id": "GO:0001641", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001641", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEI2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEI2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 220, "end_pos": 222, "annotation": "n_glycosylation_sequon" }, { "start_pos": 303, "end_pos": 305, "annotation": "n_glycosylation_sequon" }, { "start_pos": 355, "end_pos": 357, "annotation": "n_glycosylation_sequon" }, { "start_pos": 419, "end_pos": 421, "annotation": "n_glycosylation_sequon" }, { "start_pos": 497, "end_pos": 499, "annotation": "n_glycosylation_sequon" }, { "start_pos": 560, "end_pos": 562, "annotation": "n_glycosylation_sequon" }, { "start_pos": 606, "end_pos": 608, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AEI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEI2" }, { "id": "PS50259", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50259" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 3 profile", "eco_id": "ECO_0000259", "start_pos": 580, "end_pos": 846, "start_aa": "Trp", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 220, "end_pos": 222 }, { "start_pos": 303, "end_pos": 305 }, { "start_pos": 355, "end_pos": 357 }, { "start_pos": 419, "end_pos": 421 }, { "start_pos": 497, "end_pos": 499 }, { "start_pos": 560, "end_pos": 562 }, { "start_pos": 606, "end_pos": 608 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AEI3-1", "uniprot_ac": "A0A8V1AEI3", "uniprot_id": "A0A8V1AEI3_CHICK", "mass": { "chemical_mass": 78455.0, "monoisotopic_mass": 78455.0 }, "refseq": {}, "gene_names": [ { "name": "PLIN3", "type": "recommended", "evidence": [ { "id": "A0A8V1AEI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEI3" } ] } ], "protein_names": [ { "name": "Perilipin 3", "type": "synonym", "evidence": [ { "id": "A0A8V1AEI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEI3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEI3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEI3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PLIN3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEI3", "locus": {} } ], "crossref": [ { "id": "A0A8V1AEI3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AEI3", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR004279", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004279", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:420156", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420156", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1AEI3", "url": "https://www.orthodb.org/?gene=A0A8V1AEI3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AJ58", "url": "https://www.orthodb.org/?gene=A0A8V1AJ58", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14024", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14024", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14024:SF51", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14024:SF51", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03036", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03036", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1AEI3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEI3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AEI3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEI3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJ58", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ58", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJ58-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ58-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPLFFNLSATVDFTMASKQIPKKDQEAEEQQQESAVNRITNLPLLNSAFNLASSAYSSTKEMHPCLSGVCSVAETVAAVAVGSVVGGAQPILNQLDSQITLVNEYACKTLDQLEENLPFLQQPADKVFSDTKQLVSTKVTSAMNAACEAKEAMADKVTEAVDLTKNAVGDGVKLTRSMVISRVNNTVEAAQGAKDLVTNKVTEAVDLTKHIVEDSIGMTKSAVANTIVNAVEAAQGAKDLVSNKVTEALDLTKHIVEDSVGLTKSVVTSTIVSAVEAAQGTKDLVNNKVTEAVDLSKHIVEDSMGLTKSAVANTIVSAVEVAQSAKDLVTNKVIEAVDLTKVAVQDGVEKTKSAVTSTVSTALDAAYSTIASKINTALEQSREAIQESVEITNSVVTNSVSKAKVVGQAVAGGVESVLGISEDLVDHYLPMTEEELGELATAVEGFGMASVEEQRQQQSYFVRLGSLSKKVRYRAYQLSLNKLQHVKQSTQNTLSQLQLAINLIESVKKEVGQKLLDGQEKLHQLWVSWCLTQPKGHQVKTAAKVEIESRTLAMLHIITQQLQPIYESLKVSIHGLPRNIQEAVHQATRNIKKLHTTFASANSFQDLSSTTLTKSQNRVAEAQRSLDVLFEYVTQNTPLNWLVGPFKAVAEVSQDSRKGKKDKSNIKSFALEKAASSKKVTKRPEEPKGAKMILGEACGMLEKLEEKISAEEALAVKEIITNALKEDP", "length": 728, "header": "tr|A0A8V1AEI3-1|A0A8V1AEI3_CHICK Isoform 1 of Perilipin 3 OS=Gallus gallus OX=9031 GN=PLIN3 PE=1 SV=1 CANONICAL=A0A8V1AEI3-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AEI3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEI3/entry#A0A8V1AEI3-1", "sequence": { "sequence": "MPLFFNLSATVDFTMASKQIPKKDQEAEEQQQESAVNRITNLPLLNSAFNLASSAYSSTKEMHPCLSGVCSVAETVAAVAVGSVVGGAQPILNQLDSQITLVNEYACKTLDQLEENLPFLQQPADKVFSDTKQLVSTKVTSAMNAACEAKEAMADKVTEAVDLTKNAVGDGVKLTRSMVISRVNNTVEAAQGAKDLVTNKVTEAVDLTKHIVEDSIGMTKSAVANTIVNAVEAAQGAKDLVSNKVTEALDLTKHIVEDSVGLTKSVVTSTIVSAVEAAQGTKDLVNNKVTEAVDLSKHIVEDSMGLTKSAVANTIVSAVEVAQSAKDLVTNKVIEAVDLTKVAVQDGVEKTKSAVTSTVSTALDAAYSTIASKINTALEQSREAIQESVEITNSVVTNSVSKAKVVGQAVAGGVESVLGISEDLVDHYLPMTEEELGELATAVEGFGMASVEEQRQQQSYFVRLGSLSKKVRYRAYQLSLNKLQHVKQSTQNTLSQLQLAINLIESVKKEVGQKLLDGQEKLHQLWVSWCLTQPKGHQVKTAAKVEIESRTLAMLHIITQQLQPIYESLKVSIHGLPRNIQEAVHQATRNIKKLHTTFASANSFQDLSSTTLTKSQNRVAEAQRSLDVLFEYVTQNTPLNWLVGPFKAVAEVSQDSRKGKKDKSNIKSFALEKAASSKKVTKRPEEPKGAKMILGEACGMLEKLEEKISAEEALAVKEIITNALKEDP", "length": 728, "header": "tr|A0A8V1AEI3-1|A0A8V1AEI3_CHICK Isoform 1 of Perilipin 3 OS=Gallus gallus OX=9031 GN=PLIN3 PE=1 SV=1 CANONICAL=A0A8V1AEI3-1" }, "locus": { "chromosome": "28", "start_pos": 5306395, "end_pos": 5302023, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069119.1", "url": "https://www.ensembl.org/id/ENSGALT00010069119.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042561.1", "url": "https://www.ensembl.org/id/ENSGALP00010042561.1" } ] } }, { "isoform_ac": "A0A8V1AJ58-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEI3/entry#A0A8V1AJ58-1", "sequence": { "sequence": "MASKQIPKKDQEAEEQQQEVFSDTKQLVSTKVTSAMNAACEAKEAMADKVTEAVDLTKNAVGDGVKLTRSMVISRVNNTVEAAQGAKDLVTNKVTEAVDLTKHIVEDSIGMTKSAVANTIVNAVEAAQGAKDLVSNKVTEALDLTKHIVEDSVGLTKSVVTSTIVSAVEAAQGTKDLVNNKVTEAVDLSKHIVEDSMGLTKSAVANTIVSAVEVAQSAKDLVTNKVIEAVDLTKVAVQDGVEKTKSAVTSTVSTALDAAYSTIASKINTALEQSREAIQESVEITNSVVTNSVSKAKVVGQAVAGGVESVLGISEDLVDHYLPMTEEELGELATAVEGFGMASVEEQRQQQSYFVRLGSLSKKVRYRAYQLSLNKLQHVKQSTQNTLSQLQLAINLIESVKKEVGQKLLDGQEKLHQLWVSWCLTQPKGHQVKTAAKVEIESRTLAMLHIITQQLQPIYESLKVSIHGLPRNIQEAVHQATRNIKKLHTTFASANSFQDLSSTTLTKSQNRVAEAQRSLDVLFEYVTQNTPLNWLVGPFKAVAEVSQDSRKGKKDKSNIKSFALEKAASSKKVTKRPEEPKGAKMILGEACGMLEKLEEKISAEEALAVKEIITNALKEDP", "length": 621, "header": "tr|A0A8V1AJ58-1|A0A8V1AEI3_CHICK Computationally mapped isoform of Perilipin 3 OS=Gallus gallus OX=9031 GN=PLIN3 PE=1 SV=1 CANONICAL=A0A8V1AEI3-1" }, "locus": { "chromosome": "28", "start_pos": 5306395, "end_pos": 5302065, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069120.1", "url": "https://www.ensembl.org/id/ENSGALT00010069120.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042562.1", "url": "https://www.ensembl.org/id/ENSGALP00010042562.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:420156", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420156", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "lipid droplet", "id": "GO:0005811", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005811", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEI3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEI3" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEI3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEI3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "positive regulation of triglyceride storage", "id": "GO:0010890", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010890", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEI3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEI3" } ], "pmid": "" }, { "name": "lipid storage", "id": "GO:0019915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019915", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEI3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEI3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 184, "end_pos": 186, "annotation": "n_glycosylation_sequon" }, { "start_pos": 6, "end_pos": 8, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 184, "end_pos": 186 }, { "start_pos": 6, "end_pos": 8 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", 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"field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AEL1-1", "uniprot_ac": "A0A8V1AEL1", "uniprot_id": "A0A8V1AEL1_CHICK", "mass": { "chemical_mass": 103210.0, "monoisotopic_mass": 103210.0 }, "refseq": { "ac": "XP_015155557", "name": "calcium homeostasis endoplasmic reticulum protein isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015155557" }, "gene_names": [ { "name": "CHERP", "type": "recommended", "evidence": [ { "id": "A0A8V1AEL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEL1" } ] }, { "name": "CHERP", "type": "synonym", "evidence": [ { "id": "XP_015155557", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015155557" } ] } ], "protein_names": [ { "name": "Calcium homeostasis endoplasmic reticulum protein", "type": "recommended", "evidence": [ { "id": "A0A8V1AEL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEL1/entry#names_and_taxonomy" } ] }, { "name": "SR-related CTD-associated factor 6", "type": "synonym", "evidence": [ { "id": "A0A8V1AEL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEL1/entry#names_and_taxonomy" } ] }, { "name": "calcium homeostasis endoplasmic reticulum protein isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015155557", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015155557" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052559.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015155557.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015155557", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015155557" } ] }, { "annotation": "Involved in calcium homeostasis, growth and proliferation.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEL1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEL1#function" }, { "database": "UniProtKB", "id": "ARBA00054670", "url": "https://www.uniprot.org/uniprotkb/ARBA00054670#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEL1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEL1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CHERP", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEL1", "locus": { "chromosome": "28", "start_pos": 4779694, "end_pos": 4768191, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027105", "url": "https://www.ensembl.org/id/ENSGALG00010027105" } ] } } ], "crossref": [ { "id": "A0A8V1AEL1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AEL1", "database": "AlphaFoldDB", "categories": [] }, { "id": "420144", "url": "https://www.ncbi.nlm.nih.gov/gene/420144", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000061", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000061", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000467", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000467", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006569", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006569", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008942", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008942", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035967", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035967", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056721", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056721", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "QNTHHDI", "url": "https://omabrowser.org/oma/group/QNTHHDI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AEL1", "url": "https://www.orthodb.org/?gene=A0A8V1AEL1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12323", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12323", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12323:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12323:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01585", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01585", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01805", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01805", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF04818", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04818", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25127", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25127", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-72163", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72163", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9770562", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9770562", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015155557", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015155557", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AEL1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEL1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AEL1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEL1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEMPLPPDDQELRNVIDKLAQFVARNGPEFEKMTMEKQKENPKFSFLFGGDFYGYYKYKLALEQQQLLCKQNQDIEAPPQIQPLPQPSLPPAAPIPAPQGTPSVEELIQQSQWNLQQQEQQLLAMRQEQVTSAVALAIEQQMQKVLEETQLDMNEFDNLLQPIIDTCTKDAISAGKNWMFSNAKSPAHCELMAGHLRNRITAEGAHFELRLHLIYLINDVLHHCQRKQARDLLAALQKVVVPIYCTSFLAVEEDKQQKIARLLQLWEKNGYFDESIIQQLQSPALGLGQYQANLITEYATVVQPVQVAFQQQIQNLKTQHEEFVNSLTQQQQQQIQIPPLENEVKSTPPPQAPTAAPASAPPSAPVTQADDGKSQLPLAGSSEYDTTGSGVQDPASGGPRGPGSHDQIPPNKPPWFDQPHPVAPWGQQQGPPHCPPWNNNHEGMWNEQRDQGWNNQRETPWNNQPDPSWNNQFEAPWNNQHEQPPWGGGQREPPFRMQRPPHFRGPFPPHQQHPQFNQPPHPHNFNRFPPRFMQDDFPPRHPFERPPYPHRFDYPQGDFPQEIGPPHHHPGHRLPHPGISEHPPWGGPQHPDFGPPPHGFNGQPPHMRRQGPPHMNHDDPSLVPNVPYFDLPAGLMAPLVKLEDHEYKPLDPKDIRLPPPMPPSERLLAAVEAFYSPPSHDRPRNSEGWEQNGLYEFFRAKMRARRRKGQEKRNSGPSRSRSRSKSRGRSSSRSNSRSSKSSGSYSRSRSRSCSRSRSYSRSQSRSRSRSRSSHSRSRSRSRSRSKSYSPGRRRRSRSRSPTPPSSAGLGSSSGPPIPESRLGEENKGHQMLVKMGWSGSGGLGAKEQGIQDPIKGGDIRDKWDQYKGVGVALDDPYENYRRNKSYSFIARMKARDELKRETQDPPPPE", "length": 909, "header": "tr|A0A8V1AEL1-1|A0A8V1AEL1_CHICK Isoform 1 of Calcium homeostasis endoplasmic reticulum protein OS=Gallus gallus OX=9031 GN=CHERP PE=1 SV=1 CANONICAL=A0A8V1AEL1-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AEL1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEL1/entry#A0A8V1AEL1-1", "sequence": { "sequence": "MEMPLPPDDQELRNVIDKLAQFVARNGPEFEKMTMEKQKENPKFSFLFGGDFYGYYKYKLALEQQQLLCKQNQDIEAPPQIQPLPQPSLPPAAPIPAPQGTPSVEELIQQSQWNLQQQEQQLLAMRQEQVTSAVALAIEQQMQKVLEETQLDMNEFDNLLQPIIDTCTKDAISAGKNWMFSNAKSPAHCELMAGHLRNRITAEGAHFELRLHLIYLINDVLHHCQRKQARDLLAALQKVVVPIYCTSFLAVEEDKQQKIARLLQLWEKNGYFDESIIQQLQSPALGLGQYQANLITEYATVVQPVQVAFQQQIQNLKTQHEEFVNSLTQQQQQQIQIPPLENEVKSTPPPQAPTAAPASAPPSAPVTQADDGKSQLPLAGSSEYDTTGSGVQDPASGGPRGPGSHDQIPPNKPPWFDQPHPVAPWGQQQGPPHCPPWNNNHEGMWNEQRDQGWNNQRETPWNNQPDPSWNNQFEAPWNNQHEQPPWGGGQREPPFRMQRPPHFRGPFPPHQQHPQFNQPPHPHNFNRFPPRFMQDDFPPRHPFERPPYPHRFDYPQGDFPQEIGPPHHHPGHRLPHPGISEHPPWGGPQHPDFGPPPHGFNGQPPHMRRQGPPHMNHDDPSLVPNVPYFDLPAGLMAPLVKLEDHEYKPLDPKDIRLPPPMPPSERLLAAVEAFYSPPSHDRPRNSEGWEQNGLYEFFRAKMRARRRKGQEKRNSGPSRSRSRSKSRGRSSSRSNSRSSKSSGSYSRSRSRSCSRSRSYSRSQSRSRSRSRSSHSRSRSRSRSRSKSYSPGRRRRSRSRSPTPPSSAGLGSSSGPPIPESRLGEENKGHQMLVKMGWSGSGGLGAKEQGIQDPIKGGDIRDKWDQYKGVGVALDDPYENYRRNKSYSFIARMKARDELKRETQDPPPPE", "length": 909, "header": "tr|A0A8V1AEL1-1|A0A8V1AEL1_CHICK Isoform 1 of Calcium homeostasis endoplasmic reticulum protein OS=Gallus gallus OX=9031 GN=CHERP PE=1 SV=1 CANONICAL=A0A8V1AEL1-1" }, "locus": { "chromosome": "28", "start_pos": 4778623, "end_pos": 4768233, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065689.1", "url": "https://www.ensembl.org/id/ENSGALT00010065689.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039955.1", "url": "https://www.ensembl.org/id/ENSGALP00010039955.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 101, "start_aa": "Thr", "end_pos": 101, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr101", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 802, "start_aa": "Thr", "end_pos": 802, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr802", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-GGA-72163", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72163", "resource": "Reactome", "description": "mRNA Splicing - Major Pathway" }, { "id": "R-GGA-9770562", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9770562", "resource": "Reactome", "description": "mRNA Polyadenylation" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZAX5-1", "protein_name": "Calcium homeostasis endoplasmic reticulum protein", "gene_name": "Cherp", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEMPLPPDDQELRNVIDKLAQFVARNGPEFEKMTMEKQKDNPKFSFLFGGEFYSYYKCKLALEQQQLICKQQAPELEPTSAMPPLPQPPLAPTASLTPAQGTPSMDELIQQSQWSLQQQEQHLLALRQEQVTTAVAHAVEQQMQKLLEETQLDMSEFDNLLQPIIDTCTKDAISAGKNWMFSNAKSPPHCELMAGHLRNRITADGAHFELRLHLIYLINDVLHHWSLPHSQRKQARELLAALQKVVVPIYCTSFLAVEEDKQQKIARLLQLWEKNGYFDDSIIQQLQSPALGLGQYQATLINEYSSVVQPVQLAFQQQIQSLKTQHEEFVSSLAQQQQQQQQQQQPPQQPPQPQIQLPPMEADVKATPPPSAPPPASAPAPTIPPTTQPDDNKPPIQMPGSSEYDTSAGVQDPAAAGPRGPGPHEQIPPNKPPWFDQPHPVAPWGQQQPPEQPPYPHHQGGPPHCPPWNNSHEGMWGEQRGDPGWNGQRDAPWNNQPDPNWNNQFEGPWNNQHEPPPWGGAQREPPFRMQRPPHFRGPFPPHQQHPQFNQPPHPHNFNRFPPRFMQDDFPPRHPFERPPYPHRFDYPQGDFPADMGPPHHHPGHRMPHPGINEHPPWAGPQHPDFGPPPHGFNGQPPHMRRQGPPHINHDDPSLVPNVPYFDLPAGLMAPLVKLEDHEYKPLDPKDIRLPPPMPPSERLLAAVEAFYSPPSHDRPRNSEGWEQNGLYEFFRAKMRARRRKGQEKRNSGPSRSHSRSKSRGRSSSRSSSRSSKSSRSSSRSRSRSRSRSSSRSRSRSRSRSRSSRSRSRSRSRSRSKSYSPGRRRRSRSRSPTPPSAAGLGSNSAPPIPDSRLGEENKGHQMLVKMGWSGSGGLGAKEQGIQDPIKGGDVRDKWDQYKGVGVALDDPYENYRRNKSYSFIARMKARDEFSTFGARKEEKED", "length": 940 }, "evidence": [ { "id": "A0A8V1AEL1", "url": "https://omabrowser.org/oma/group/A0A8V1AEL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q59E33-1", "protein_name": "SR-related CTD associated factor 6, isoform A", "gene_name": "scaf6", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDVQPPRDASLRNIIDKLAEFVARNGPEFEAITKQKQQNNPKFEFLYGGEFANYYQFRVAAEQALLKQQAINQQLPPGAPSGHYMQHPPPMQQSQPPGLYPPPNQQPPHPPETAQDNMQQQTQHSWPPNSGNGGPPNNQQANGNPMAMNLTSQLEAIKMQQKSLREQIQQSEANLSAQHTALMNQKTKQIEDAIAAAQTAQQEQMAGEQGIVLRDFDGVLQPIIESCTKDSISAGKNWILQHSTDSAKINVVLQYLLKKALVNGSTFQQKLHLIYLVNDILHHCMRKNINDLKNSLENVVIPMFCSADLIGNPDQRQKLAKLLSLWESKAKFFDACVISKLQSPDSSMQEYKTNLQNTHHDITAKFTQNTKATLDNYQKQHHVFIQHASQQIVQLEKQAQHLEQQIVAQKSQQQHMLQHQQKNIPSLMSHRIAMPGDHEHMNSQGPHDQQHPQAGNNMYPGGNFQQQQPPPGNHFADPRGPNFFIPDMSKPPPGFPGPMHHNQGPAMGQQQPQPGQFPPMQAPGSGNEPPVDLGVLSAAIQACLQMQQQHHPDDPQQQGQHQLQQQQQQQPQQQKQPPPMAAYPQNIVRPGQQNADSSEVDLDVLNAAIRAVITNKPEDGTLEDGQQPQKLVDGESGEPVVIGEPQIPTAPYYDLPAGLMVPLIRLEDYNYKALDPADIRLPAPAPQSERLTNALNAFYSAPSHDRPRDNEGWEKLGLYEYYKVKNAARKQKEEEIKDGIREKSRSPSPIVLEKPLPKKSNKRVYRSKSRSRSRSKTPPHRDRSLSRSRSRSRSMERSLTPPPMNRSRLGGGNNRKGRNRSPRHERDNNSGSTNTREGRGDRGNSNSRDNGNSTNLRRVDRDRSLTPPSFLGSTFAKPADFIEESNKGHQMLMKMGWAGTGTGLGSKNQGIDTPISGGEVRDRREMYKGVGANMHDPFESFRKNKGAAFAHRMRSRDDKS", "length": 960 }, "evidence": [ { "id": "A0A8V1AEL1", "url": "https://omabrowser.org/oma/group/A0A8V1AEL1/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q8CGZ0-1", "protein_name": "Calcium homeostasis endoplasmic reticulum protein", "gene_name": "Cherp", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEMPMPPDDQELRNVIDKLAQFVARNGPEFEKMTMEKQKDNPKFSFLFGGEFYSYYKCKLALEQQQLICKQQAPELEPTSAMPPLPQPPLAPTASLTPAQGTPSMDELIQQSQWSLQQQEQHLLALRQEQVTTAVAHAVEQQMQKLLEETQLDMSEFDNLLQPIIDTCTKDAISAGKNWMFSNAKSPPHCELMAGHLRNRITADGAHFELRLHLIYLINDVLHHCQRKQARELLAALQKVVVPIYCTSFLAVEEDKQQKIARLLQLWEKNGYFDDSIIQQLQSPALGLGQYQATLINEYSSVVQPVQLAFQQQIQSLKTQHEEFVSSLAQQQQQQQQQQQQQPQPQPQPQIQLPQMEADVKATPPPPAPPPASAPAPTIPPTTQPDDNKPPIQMPGSSEYDTSAGVQDPAAAGPRGPGPHEQIPPNKPPWFDQPHPVAPWGQQQPPEQPPYPHHQGGPPHCPPWNNSHEGMWGEQRGDPGWNGQRDAPWNNQPDPNWNNQFEGPWNNQHEPPPWGGAQREPPFRMQRPPHFRGPFPPHQQHPQFNQPPHPHNFNRFPPRFMQDDFPPRHPFERPPYPHRFDYPQGDFPADMGPPHHHPGHRMPHPGINEHPPWAGPQHPDFGPPPHGFNGQPPHMRRQGPPHINHDDPSLVPNVPYFDLPAGLMAPLVKLEDHEYKPLDPKDIRLPPPMPPSERLLAAVEAFYSPPSHDRPRNSEGWEQNGLYEFFRAKMRARRRKGQEKRNSGPSRSRSRSKSRGRSSSRSSSRSSKSSRSSSRSHSRSRSRSSSRSRSRSRSRSRSSRSRSRSRSRSRSKSYSPGRRRRSRSRSPTPPSAAGLGSNSAPPIPDSRLGEENKGHQMLVKMGWSGSGGLGAKEQGIQDPIKGGDVRDKWDQYKGVGVALDDPYENYRRNKSYSFIARMKARDEFSTFGTRKEEKED", "length": 936 }, "evidence": [ { "id": "A0A8V1AEL1", "url": "https://omabrowser.org/oma/group/A0A8V1AEL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8IWX8-1", "protein_name": "Calcium homeostasis endoplasmic reticulum protein", "gene_name": "CHERP", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEMPLPPDDQELRNVIDKLAQFVARNGPEFEKMTMEKQKDNPKFSFLFGGEFYSYYKCKLALEQQQLICKQQTPELEPAATMPPLPQPPLAPAAPIPPAQGAPSMDELIQQSQWNLQQQEQHLLALRQEQVTAAVAHAVEQQMQKLLEETQLDMNEFDNLLQPIIDTCTKDAISAGKNWMFSNAKSPPHCELMAGHLRNRITADGAHFELRLHLIYLINDVLHHCQRKQARELLAALQKVVVPIYCTSFLAVEEDKQQKIARLLQLWEKNGYFDDSIIQQLQSPALGLGQYQATLINEYSSVVQPVQLAFQQQIQTLKTQHEEFVTSLAQQQQQQQQQQQQLQMPQMEAEVKATPPPPAPPPAPAPAPAIPPTTQPDDSKPPIQMPGSSEYEAPGGVQDPAAAGPRGPGPHDQIPPNKPPWFDQPHPVAPWGQQQPPEQPPYPHHQGGPPHCPPWNNSHEGMWGEQRGDPGWNGQRDAPWNNQPDAAWNSQFEGPWNSQHEQPPWGGGQREPPFRMQRPPHFRGPFPPHQQHPQFNQPPHPHNFNRFPPRFMQDDFPPRHPFERPPYPHRFDYPQGDFPAEMGPPHHHPGHRMPHPGINEHPPWAGPQHPDFGPPPHGFNGQPPHMRRQGPPHINHDDPSLVPNVPYFDLPAGLMAPLVKLEDHEYKPLDPKDIRLPPPMPPSERLLAAVEAFYSPPSHDRPRNSEGWEQNGLYEFFRAKMRARRRKGQEKRNSGPSRSRSRSKSRGRSSSRSNSRSSKSSGSYSRSRSRSCSRSYSRSRSRSRSRSRSSRSRSRSQSRSRSKSYSPGRRRRSRSRSPTPPSSAGLGSNSAPPIPDSRLGEENKGHQMLVKMGWSGSGGLGAKEQGIQDPIKGGDVRDKWDQYKGVGVALDDPYENYRRNKSYSFIARMKARDECK", "length": 916 }, "evidence": [ { "id": "A0A8V1AEL1", "url": "https://omabrowser.org/oma/group/A0A8V1AEL1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEL1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEL1" } ], "pmid": "" }, { "name": "transmembrane transporter binding", "id": "GO:0044325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044325", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEL1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEL1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEL1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEL1" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEL1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEL1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "RNA processing", "id": "GO:0006396", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006396", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEL1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEL1" } ], "pmid": "" }, { "name": "intracellular calcium ion homeostasis", "id": "GO:0006874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006874", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEL1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEL1" } ], "pmid": "" }, { "name": "release of sequestered calcium ion into cytosol", "id": "GO:0051209", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051209", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEL1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEL1" } ], "pmid": "" }, { "name": "positive regulation of calcineurin-NFAT signaling cascade", "id": "GO:0070886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEL1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEL1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 883, "end_pos": 885, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AEL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEL1" }, { "id": "PS51391", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51391" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CID", "eco_id": "ECO_0000259", "start_pos": 148, "end_pos": 288, "start_aa": "Glu", "end_aa": "Gly", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1AEL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEL1" }, { "id": "PS50174", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50174" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-patch", "eco_id": "ECO_0000259", "start_pos": 824, "end_pos": 874, "start_aa": "Glu", "end_aa": "Asp", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1AEL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEL1" }, { "id": "PS50128", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50128" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SURP motif", "eco_id": "ECO_0000259", "start_pos": 15, "end_pos": 57, "start_aa": "Val", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 101, 802 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 883, "end_pos": 885 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AEP5-1", "uniprot_ac": "A0A8V1AEP5", "uniprot_id": "A0A8V1AEP5_CHICK", "mass": { "chemical_mass": 68289.0, "monoisotopic_mass": 68289.0 }, "refseq": { "ac": "XP_004945797", "name": "kelch-like protein 13 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004945797" }, "gene_names": [ { "name": "LOC101748328", "type": "recommended", "evidence": [ { "id": "A0A8V1AEP5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEP5" } ] }, { "name": "LOC101748328", "type": "synonym", "evidence": [ { "id": "XP_004945797", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004945797" } ] } ], "protein_names": [ { "name": "BTB domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8V1AEP5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEP5/entry#names_and_taxonomy" } ] }, { "name": "kelch-like protein 13 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_004945797", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004945797" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052548.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004945797.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004945797", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004945797" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEP5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEP5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC101748328", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEP5", "locus": {} } ], "crossref": [ { "id": "A0A8V1AEP5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AEP5", "database": "AlphaFoldDB", "categories": [] }, { "id": "101748328", "url": "https://www.ncbi.nlm.nih.gov/gene/101748328", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006652", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006652", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011705", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011705", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015915", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015915", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017096", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017096", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056737", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056737", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:101748328", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:101748328", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "THKGILY", "url": "https://omabrowser.org/oma/group/THKGILY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AEP5", "url": "https://www.orthodb.org/?gene=A0A8V1AEP5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45632", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45632", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45632:SF15", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45632:SF15", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00651", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00651", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07707", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07707", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24981", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24981", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004945797", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004945797", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AEP5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEP5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AEP5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEP5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGSLGSDTYLEKLLEGISRLRTQKALCDVTLEAEGVCFPAHKIILASASNYCKILFVGNATRTGSTDGSVHLNAVSAVGLSNVLSFIYSNKLDLSLQNVEETFKAAEALLVGEVIKLCFRFLESCLSSENCVDVLRIAKKLGPTELREKAMSCVRQHYKQLLADPQSLKDLDRGTLCEILDRTTAEGSGELELLRAAVSWLQHDRTRLKYMGDILKRIGFPLVPFRELQRYAQEIPLTRLDWGCRRLLQDALTHHPQLCTQRPRQTPHTALCSTSPALLIAGGRTTTNSICREMWAAEQSCGTWRKVGDLCVPLYNHCIVVIEDFLFVLGGQSMFDPTGKQPSNEVFRFDPCNASWLQLASMLQRRTRFHADVLSDHIFVVGGGTLLGTLTHTVESYQPAANKWEFAAPFPIPIADHAGTTHEGILYISGGFSAGRTLPDTFSFLPRLRRWAHNRAMTFPRCDHGMAATKDGIFCIGGRTLKGVEQWIHVSETECYCPVSDQWTTLTLSPFSRCQFSVTAHRSTLYLTGGGLLQHMRKEDSVYLYDTEGQVWKRAGPLPRALVDHASCMVKLPQANAAGEPRRGTERRLTSRRQKATLSLLAAKRQGPSTASKGK", "length": 615, "header": "tr|A0A8V1AEP5-1|A0A8V1AEP5_CHICK Isoform 1 of BTB domain-containing protein OS=Gallus gallus OX=9031 GN=LOC101748328 PE=4 SV=1 CANONICAL=A0A8V1AEP5-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AEP5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEP5/entry#A0A8V1AEP5-1", "sequence": { "sequence": "MGSLGSDTYLEKLLEGISRLRTQKALCDVTLEAEGVCFPAHKIILASASNYCKILFVGNATRTGSTDGSVHLNAVSAVGLSNVLSFIYSNKLDLSLQNVEETFKAAEALLVGEVIKLCFRFLESCLSSENCVDVLRIAKKLGPTELREKAMSCVRQHYKQLLADPQSLKDLDRGTLCEILDRTTAEGSGELELLRAAVSWLQHDRTRLKYMGDILKRIGFPLVPFRELQRYAQEIPLTRLDWGCRRLLQDALTHHPQLCTQRPRQTPHTALCSTSPALLIAGGRTTTNSICREMWAAEQSCGTWRKVGDLCVPLYNHCIVVIEDFLFVLGGQSMFDPTGKQPSNEVFRFDPCNASWLQLASMLQRRTRFHADVLSDHIFVVGGGTLLGTLTHTVESYQPAANKWEFAAPFPIPIADHAGTTHEGILYISGGFSAGRTLPDTFSFLPRLRRWAHNRAMTFPRCDHGMAATKDGIFCIGGRTLKGVEQWIHVSETECYCPVSDQWTTLTLSPFSRCQFSVTAHRSTLYLTGGGLLQHMRKEDSVYLYDTEGQVWKRAGPLPRALVDHASCMVKLPQANAAGEPRRGTERRLTSRRQKATLSLLAAKRQGPSTASKGK", "length": 615, "header": "tr|A0A8V1AEP5-1|A0A8V1AEP5_CHICK Isoform 1 of BTB domain-containing protein OS=Gallus gallus OX=9031 GN=LOC101748328 PE=4 SV=1 CANONICAL=A0A8V1AEP5-1" }, "locus": { "chromosome": "17", "start_pos": 1000578, "end_pos": 995408, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067960.1", "url": "https://www.ensembl.org/id/ENSGALT00010067960.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041703.1", "url": "https://www.ensembl.org/id/ENSGALP00010041703.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:101748328", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:101748328", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 353, "end_pos": 355, "annotation": "n_glycosylation_sequon" }, { "start_pos": 59, "end_pos": 61, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AEP5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEP5" }, { "id": "PS50097", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50097" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BTB", "eco_id": "ECO_0000259", "start_pos": 27, "end_pos": 96, "start_aa": "Cys", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 353, "end_pos": 355 }, { "start_pos": 59, "end_pos": 61 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AEP6-1", "uniprot_ac": "A0A8V1AEP6", "uniprot_id": "A0A8V1AEP6_CHICK", "mass": { "chemical_mass": 69671.0, "monoisotopic_mass": 69671.0 }, "refseq": { "ac": "XP_015151368", "name": "nuclear fragile X mental retardation-interacting protein 2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015151368" }, "gene_names": [ { "name": "NUFIP2", "type": "recommended", "evidence": [ { "id": "A0A8V1AEP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEP6" } ] }, { "name": "NUFIP2", "type": "synonym", "evidence": [ { "id": "XP_015151368", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015151368" } ] } ], "protein_names": [ { "name": "Nuclear FMR1 interacting protein 2", "type": "synonym", "evidence": [ { "id": "A0A8V1AEP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEP6/entry#names_and_taxonomy" } ] }, { "name": "nuclear fragile X mental retardation-interacting protein 2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015151368", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015151368" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052550.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015151368.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015151368", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015151368" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEP6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEP6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NUFIP2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEP6", "locus": { "chromosome": "19", "start_pos": 6435010, "end_pos": 6467490, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029691", "url": "https://www.ensembl.org/id/ENSGALG00010029691" } ] } } ], "crossref": [ { "id": "A0A8V1AEP6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AEP6", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd06747", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06747", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "417582", "url": "https://www.ncbi.nlm.nih.gov/gene/417582", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001478", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001478", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032747", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032747", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036034", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036034", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051067", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051067", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:417582", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417582", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NEQKGNR", "url": "https://omabrowser.org/oma/group/NEQKGNR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AEP6", "url": "https://www.orthodb.org/?gene=A0A8V1AEP6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ALQ0", "url": "https://www.orthodb.org/?gene=A0A8V1ALQ0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AND0", "url": "https://www.orthodb.org/?gene=A0A8V1AND0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1APT7", "url": "https://www.orthodb.org/?gene=A0A8V1APT7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14191", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14191", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14191:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14191:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR28333", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28333", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR28333:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28333:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00595", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00595", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF15293", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15293", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015151368", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015151368", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AEP6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEP6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AEP6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEP6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALQ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALQ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALQ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALQ0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AND0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AND0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AND0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AND0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1APT7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APT7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1APT7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APT7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEEQPPHHPHHHHHPHHHHHHHPHHRHFCYYPQSAFLPPPDGRAQPKATLRHPEGPKRRTGYGELNGNAGDREVSLKALCSEETASPTSRVPNGSQQLADANVTPKPSVKGSSLGKAAIKPKNFVQKNSMDKKNEKPYDSKAREGQPADKQDGLSVPNGVVSGGAAYITNGFVGKGADNDGSGSESGYTTPKKRKGRRNSAKGCESLNLVQDKAVQQEVGTALKQELESFKPDYSEQKGNRIESTKPVWKYEAGGGGAGRGRPGLSDVQRKNSDAKAGIGGKKFDERPKGKHASPAASKEDSWTLFKPPPVFPVDNSSAKIVPKISYASKVKENLNKAAQPPSASSSSSSSSSSSAGEAQPAPAGRLSQVPMSAMKSVTSAGFSNGPLLAGADGAAYPPGAQPLLASAAAAVPPAPADAVPPDVGAAPAAAEQKKSNLFIYPSDMQTALLGTAQVDFPSQANQQNLGDIFQNQWGLSFINEPSAGPEAAAGKSADNPSMEVTFQGEYPAASGSHGAEAVPSGAEQPAFPKAYELDKRTNPSPALSAAPKPGTAGEGGGAAPEPHHPGELQKADAGSQGALVFLSKDYEVENPLASPTNNLLSSAKEQGYQRGLERKDSWGSFDLSAAVKYHTKEMEAVWNLQKQDPKRIITYDEAMDHPDQ", "length": 661, "header": "tr|A0A8V1AEP6-1|A0A8V1AEP6_CHICK Isoform 1 of Nuclear FMR1 interacting protein 2 OS=Gallus gallus OX=9031 GN=NUFIP2 PE=1 SV=1 CANONICAL=A0A8V1AEP6-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AEP6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEP6/entry#A0A8V1AEP6-1", "sequence": { "sequence": "MEEQPPHHPHHHHHPHHHHHHHPHHRHFCYYPQSAFLPPPDGRAQPKATLRHPEGPKRRTGYGELNGNAGDREVSLKALCSEETASPTSRVPNGSQQLADANVTPKPSVKGSSLGKAAIKPKNFVQKNSMDKKNEKPYDSKAREGQPADKQDGLSVPNGVVSGGAAYITNGFVGKGADNDGSGSESGYTTPKKRKGRRNSAKGCESLNLVQDKAVQQEVGTALKQELESFKPDYSEQKGNRIESTKPVWKYEAGGGGAGRGRPGLSDVQRKNSDAKAGIGGKKFDERPKGKHASPAASKEDSWTLFKPPPVFPVDNSSAKIVPKISYASKVKENLNKAAQPPSASSSSSSSSSSSAGEAQPAPAGRLSQVPMSAMKSVTSAGFSNGPLLAGADGAAYPPGAQPLLASAAAAVPPAPADAVPPDVGAAPAAAEQKKSNLFIYPSDMQTALLGTAQVDFPSQANQQNLGDIFQNQWGLSFINEPSAGPEAAAGKSADNPSMEVTFQGEYPAASGSHGAEAVPSGAEQPAFPKAYELDKRTNPSPALSAAPKPGTAGEGGGAAPEPHHPGELQKADAGSQGALVFLSKDYEVENPLASPTNNLLSSAKEQGYQRGLERKDSWGSFDLSAAVKYHTKEMEAVWNLQKQDPKRIITYDEAMDHPDQ", "length": 661, "header": "tr|A0A8V1AEP6-1|A0A8V1AEP6_CHICK Isoform 1 of Nuclear FMR1 interacting protein 2 OS=Gallus gallus OX=9031 GN=NUFIP2 PE=1 SV=1 CANONICAL=A0A8V1AEP6-1" }, "locus": { "chromosome": "19", "start_pos": 6467375, "end_pos": 6458713, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071811.1", "url": "https://www.ensembl.org/id/ENSGALT00010071811.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044501.1", "url": "https://www.ensembl.org/id/ENSGALP00010044501.1" } ] } }, { "isoform_ac": "A0A8V1ALQ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEP6/entry#A0A8V1ALQ0-1", "sequence": { "sequence": "MEEQPPHHPHHHHHPHHHHHHHPHHRHFCYYPQSAFLPPPDGRAQPKATLRHPEGPKRRTGYGELNGNAGDREVSLKALCSEETASPTSRVPNGSQQLADANVTPKPSVKGSSLGKAAIKPKNFVQKNSMDKKNEKPYDSKAREGQPADKQDGLSVPNGVVSGGAAYITNGFVGKGADNDGSGSESGYTTPKKRKGRRNSAKGCESLNLVQDKAVQQEVGTALKQELESFKPDYSEQKGNRIESTKPGLSDVQRKNSDAKAGIGGKKFDERPKGKHASPAASKEDSWTLFKPPPVFPVDNSSAKIVPKISYASKVKENLNKAAQPPSASSSSSSSSSSSAGEAQPAPAGRLSQVPMSAMKSVTSAGFSNGPLLAGADGAAYPPGAQPLLASAAAAVPPAPADAVPPDVGAAPAAAEQKKSNLFIYPSDMQTALLGTAQVDFPSQANQQNLGDIFQNQWGLSFINEPSAGPEAAAGKSADNPSMEVTFQGEYPAASGSHGAEAVPSGAEQPAFPKAYELDKRTNPSPALSAAPKPGTAGEGGGAAPEPHHPGELQKADAGSQGALVFLSKDYEVENPLASPTNNLLSSAKEQGYQRGLERKDSWGSFDLSAAVKYHTKEMEAVWNLQKQDPKRIITYDEAMDHPDQ", "length": 645, "header": "tr|A0A8V1ALQ0-1|A0A8V1AEP6_CHICK Computationally mapped isoform of Nuclear FMR1 interacting protein 2 OS=Gallus gallus OX=9031 GN=NUFIP2 PE=1 SV=1 CANONICAL=A0A8V1AEP6-1" }, "locus": { "chromosome": "19", "start_pos": 6467375, "end_pos": 6458713, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071810.1", "url": "https://www.ensembl.org/id/ENSGALT00010071810.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044500.1", "url": "https://www.ensembl.org/id/ENSGALP00010044500.1" } ] } }, { "isoform_ac": "A0A8V1AND0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEP6/entry#A0A8V1AND0-1", "sequence": { "sequence": "MAVWRADVFLPRNALRKWDAAFCTQKFNAARSDLCSFVSSRFLPGYGELNGNAGDREVSLKALCSEETASPTSRVPNGSQQLADANVTPKPSVKGSSLGKAAIKPKNFVQKNSMDKKNEKPYDSKAREGQPADKQDGLSVPNGVVSGGAAYITNGFVGKGADNDGSGSESGYTTPKKRKGRRNSAKGCESLNLVQDKAVQQEVGTALKQELESFKPDYSEQKGNRIESTKPVWKYEAGGGGAGRGRPGLSDVQRKNSDAKAGIGGKKFDERPKGKHASPAASKEDSWTLFKPPPVFPVDNSSAKIVPKISYASKVKENLNKAAQPPSASSSSSSSSSSSAGEAQPAPAGRLSQVPMSAMKSVTSAGFSNGPLLAGADGAAYPPGAQPLLASAAAAVPPAPADAVPPDVGAAPAAAEQKKSNLFIYPSDMQTALLGTAQVDFPSQANQQNLGDIFQNQWGLSFINEPSAGPEAAAGKSADNPSMEVTFQGEYPAASGSHGAEAVPSGAEQPAFPKAYELDKRTNPSPALSAAPKPGTAGEGGGAAPEPHHPGELQKADAGSQGALVFLSKDYEVENPLASPTNNLLSSAKEQGYQRGLERKDSWGSFDLSAAVKYHTKEMEAVWNLQKQDPKRIITYDEAMDHPDQ", "length": 645, "header": "tr|A0A8V1AND0-1|A0A8V1AEP6_CHICK Computationally mapped isoform of Nuclear FMR1 interacting protein 2 OS=Gallus gallus OX=9031 GN=NUFIP2 PE=1 SV=1 CANONICAL=A0A8V1AEP6-1" }, "locus": { "chromosome": "19", "start_pos": 6465555, "end_pos": 6458713, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071809.1", "url": "https://www.ensembl.org/id/ENSGALT00010071809.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044499.1", "url": "https://www.ensembl.org/id/ENSGALP00010044499.1" } ] } }, { "isoform_ac": "A0A8V1APT7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEP6/entry#A0A8V1APT7-1", "sequence": { "sequence": "MKAGGRATSSSTMFNLMKKDKEKDGARKEKKEKKEKKERMSAAELKSLEEMSMRRGFFNLNRASKRDSKARLEISNPIPIKVASGSDLHLTDIDSDSNRGSVILDSGHLSTASSSDDLKVDDANFKGSVLQRAAKFGSLAKQNSQMIVKRFSFSQKSRDESASETSTPSEHSAAPSPQVEVRALEAQLSKQGAPQGHPRTPPAPSTLSRPPDLVSKRFPAELRLPALVPPQPPAPRQLELQRRNTGDFGFSLRRTTMLDCAPDGQVYRRVVHFAEPGAGTKDLALGLVPGDRLVEINGKNVENKTRDEIVEMIRQSGETVQLKVQPILELSELSRCWLRGAEGTRRAAWDPGPRLHETSPWPSRPALRSGSRREVTRTKP", "length": 380, "header": "tr|A0A8V1APT7-1|A0A8V1AEP6_CHICK Computationally mapped isoform of Nuclear FMR1 interacting protein 2 OS=Gallus gallus OX=9031 GN=NUFIP2 PE=1 SV=1 CANONICAL=A0A8V1AEP6-1" }, "locus": { "chromosome": "19", "start_pos": 6458713, "end_pos": 6436014, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071812.1", "url": "https://www.ensembl.org/id/ENSGALT00010071812.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044502.1", "url": "https://www.ensembl.org/id/ENSGALP00010044502.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:417582", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417582", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0ABK0LC18-1", "protein_name": "Nuclear FMR1 interacting protein 2", "gene_name": "Nufip2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEEKPGQPQPQHHHSHHHPHHHPQQQQQQSHHHHHYYFYNHSHNHHHHHHHQQPHQYLQHGAEGSPKAQPKPLKHEQKHTLQQHQETPKKKTGYGEINGNAGEREISLKNLSSDEATNPISRVLNGNQQVVDTSLKQTVKTSTFGKAGIKTKNFIQKNSMDKKNGKSYENKSGETQAVDKTDTIAIPNGVITNNSGYITNGYMSKGADNDGSGSESGYTTPKKRKARRNSAKGCENLNLVQDKIMQETSVPALKQGLETLKPDYSEQKGTRVDGSKPIWKYETGPGGTSRGKPAMGDIIRKSSDIKPGLSSKKFDDRPKGKHASAAASKEDSWTLFKPPPVFPVDNSSAKIVPKISYASKVKENLNKTVQNSSVSPTSSSSSSSTGETQTQSSSRLSQVPMSALKSVTSASFSNGPVLAGTDGSMYPSAGQPLLTTAANTLTPISTGTDSVLQDMSLSSAAVEQIKSSLFIYPSNMQTVLLSAQVDLPSQTDQQNLGDIFQNQWGLSFINEPSAGPETVIGKSSDHKVMEVTFQGEYPATLVSQGAEIIPSGTEHPVFPKAYELEKRTSPQVLGNILKPGTTESGALSLEPSHIGDLQKADTSSQGALVFLSKDYEIENQNPLASPTNTLLGSAKEQRYQRGLERNDSWGSFDLRAAIVYHTKEMESIWNLQKQDPKRIITYNEAMDSPDQ", "length": 691 }, "evidence": [ { "id": "A0A8V1AEP6", "url": "https://omabrowser.org/oma/group/A0A8V1AEP6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1RN89-1", "protein_name": "Nuclear FMR1 interacting protein 2", "gene_name": "NUFIP2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEEKPGQPQSQHHHSHHHPHHHPQQQQQQQQQPPHHHHHYYFYNHSHNHHHHHHHQQPHQYLQHGAEGSPKAQPKPLKHEQKHALQQHQETPKKKTGYGELNGNAGEREISLKSLGSDEATNPISRVLNGNQQVVDTNLKQTVRSSTFGKAGIKTRNFIQKNSMDKKNGKSYENKSGENQSVDKTDAVAIPNGVVTNNSGYITNGYMGKGADNDGSGSESGYTTPKKRKARRNSAKGCENLNLVQDKIMQQETNVPTLKQGLETFKPDYSEQKGNRVDGSKPIWKYETGPGGTSRGKPAMGDMLRKSSDTKPGVSSKKFDDRPKGKHTSAVASKEDSWTLFKPPPVFPVDNSSAKIVPKISYASKVKENLNKTVQNSSVSPSSSSSSSSSSSAGETQTQPSSRLSQVPMSALKSVTSANFSNGPVLAGTDASVYSPGGQPLLTTAANTLAPISSGADSVLQDMSLTSAAVEQIKSSLFIYPSNMQTVLLSTAQVDLPSQTDQQNLGDIFQNQWGLSFINEPSAGPETVIGKSSDHKVMEVTFQGEYPATLVSQGAEIIPSGTEHPVFPKAYELEKRTSPQVLGSILKSGTTSESGALSLEPSHIGDLQKADTSSQGALVFLSKDYEIENQNPLASPTNTLLGSAKEQRYQRGLERNDSWGSFDLRAAIVYHTKEMESVWNLQKQVAYQINRLCILSYLITAIKRH", "length": 705 }, "evidence": [ { "id": "A0A8V1AEP6", "url": "https://omabrowser.org/oma/group/A0A8V1AEP6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q5F2E7-1", "protein_name": "FMR1-interacting protein NUFIP2", "gene_name": "Nufip2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEEKPGQPQPQHHHSHHHPHHHPQQQQQQQSHHHHHYYFYNHSHNHHHHHHHQQPHQYLQHGAEGSPKAQPKPLKHEQKHTLQQHQETPKKKTGYGEINGNAGEREISLKSLSSDEATNPISRVLNGNQQVVETSLKQTVKTSTFGKAGIKTKNFIQKNSMDKKNGKSYENKSGETQAVDKTDTIAIPNGVITSSSGYITNGYMSKGADNDGSGSESGYTTPKKRKARRNSAKGCENLNLVQDKIMQETSVPALKQGLETLKPDYSEQKGMRVDGSKPIWKYETGPGGTSRGKPAMGDVLRKSSDIKPGLSSKKFDDRPKGKHASAAASKEDSWTLFKPPPVFPVDNSSAKIVPKISYASKVKENLNKTVQNSSVSPSSSSSSSSTGETQTQSSSRLSQVPMSALKSVTSASFSNGPVLAGTDGSVYPSGGQPLLTTAANTLTPISTGTDSVLQDMSLASAAVEQIKSSLFIYPSNMQTVLLSAQVDLPSQTDQQNLGDIFQNQWGLSFINEPSAGPETVIGKSSDHKVMEVTFQGEYPATLVSQGAEIIPSGTEHPVFPKAYELEKRTSPQVLGHILKPGTTESGALSLDPSHIGDLQKADTSSQGALVFLSKDYEIENQNPLASPTNTLLGSAKEQRYQRGLERNDSWGSFDLRAAIVYHTKEMESIWNLQKQDPKRIITYNEAMDSPDQ", "length": 692 }, "evidence": [ { "id": "A0A8V1AEP6", "url": "https://omabrowser.org/oma/group/A0A8V1AEP6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7Z417-1", "protein_name": "FMR1-interacting protein NUFIP2", "gene_name": "NUFIP2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEEKPGQPQPQHHHSHHHPHHHPQQQQQQPHHHHHYYFYNHSHNHHHHHHHQQPHQYLQHGAEGSPKAQPKPLKHEQKHTLQQHQETPKKKTGYGELNGNAGEREISLKNLSSDEATNPISRVLNGNQQVVDTSLKQTVKANTFGKAGIKTKNFIQKNSMDKKNGKSYENKSGENQSVDKSDTIPIPNGVVTNNSGYITNGYMGKGADNDGSGSESGYTTPKKRKARRNSAKGCENLNIVQDKIMQQETSVPTLKQGLETFKPDYSEQKGNRVDGSKPIWKYETGPGGTSRGKPAVGDMLRKSSDSKPGVSSKKFDDRPKGKHASAVASKEDSWTLFKPPPVFPVDNSSAKIVPKISYASKVKENLNKTIQNSSVSPTSSSSSSSSTGETQTQSSSRLSQVPMSALKSVTSANFSNGPVLAGTDGNVYPPGGQPLLTTAANTLTPISSGTDSVLQDMSLTSAAVEQIKTSLFIYPSNMQTMLLSTAQVDLPSQTDQQNLGDIFQNQWGLSFINEPSAGPETVTGKSSEHKVMEVTFQGEYPATLVSQGAEIIPSGTEHPVFPKAYELEKRTSPQVLGSILKSGTTSESGALSLEPSHIGDLQKADTSSQGALVFLSKDYEIESQNPLASPTNTLLGSAKEQRYQRGLERNDSWGSFDLRAAIVYHTKEMESIWNLQKQDPKRIITYNEAMDSPDQ", "length": 695 }, "evidence": [ { "id": "A0A8V1AEP6", "url": "https://omabrowser.org/oma/group/A0A8V1AEP6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEP6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEP6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEP6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEP6" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEP6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEP6" } ], "pmid": "" }, { "name": "nuclear body", "id": "GO:0016604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016604", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEP6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEP6" } ], "pmid": "" }, { "name": "ribosome", "id": "GO:0005840", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005840", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEP6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEP6" } ], "pmid": "" }, { "name": "cytoplasmic stress granule", "id": "GO:0010494", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010494", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEP6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEP6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 102, "end_pos": 104, "annotation": "n_glycosylation_sequon" }, { "start_pos": 316, "end_pos": 318, "annotation": "n_glycosylation_sequon" }, { "start_pos": 93, "end_pos": 95, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 102, "end_pos": 104 }, { "start_pos": 316, "end_pos": 318 }, { "start_pos": 93, "end_pos": 95 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AES9-1", "uniprot_ac": "A0A8V1AES9", "uniprot_id": "A0A8V1AES9_CHICK", "mass": { "chemical_mass": 8251.0, "monoisotopic_mass": 8251.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "CTXD1 protein", "type": "recommended", "evidence": [ { "id": "A0A8V1AES9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AES9/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AES9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AES9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AES9", "locus": {} } ], "crossref": [ { "id": "A0A8V1AES9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AES9", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR020066", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020066", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR16736", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16736", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16736:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16736:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF11057", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11057", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1AES9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AES9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AES9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AES9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "LMLLLSLRPPLPCRDVAGAACLSAARMAIDVDQGFAIAFVVLTCLFLLAVMVRCAKLIIDPYSAIPTSTWEEEQIN", "length": 76, "header": "tr|A0A8V1AES9-1|A0A8V1AES9_CHICK Isoform 1 of CTXD1 protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1AES9-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AES9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AES9/entry#A0A8V1AES9-1", "sequence": { "sequence": "LMLLLSLRPPLPCRDVAGAACLSAARMAIDVDQGFAIAFVVLTCLFLLAVMVRCAKLIIDPYSAIPTSTWEEEQIN", "length": 76, "header": "tr|A0A8V1AES9-1|A0A8V1AES9_CHICK Isoform 1 of CTXD1 protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1AES9-1" }, "locus": { "chromosome": "25", "start_pos": 2577003, "end_pos": 2576491, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069201.1", "url": "https://www.ensembl.org/id/ENSGALT00010069201.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042643.1", "url": "https://www.ensembl.org/id/ENSGALP00010042643.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AES9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AES9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AET4-1", "uniprot_ac": "A0A8V1AET4", "uniprot_id": "A0A8V1AET4_CHICK", "mass": { "chemical_mass": 54958.0, "monoisotopic_mass": 54958.0 }, "refseq": { "ac": "XP_418000", "name": "protein phosphatase 1J isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418000" }, "gene_names": [ { "name": "PPM1J", "type": "recommended", "evidence": [ { "id": "A0A8V1AET4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AET4" } ] }, { "name": "PPM1J", "type": "synonym", "evidence": [ { "id": "XP_418000", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418000" } ] } ], "protein_names": [ { "name": "Protein phosphatase, Mg2+/Mn2+ dependent 1J", "type": "synonym", "evidence": [ { "id": "A0A8V1AET4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AET4/entry#names_and_taxonomy" } ] }, { "name": "protein phosphatase 1J isoform X1", "type": "synonym", "evidence": [ { "id": "XP_418000", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418000" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052557.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_418000.3. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_418000", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418000" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AET4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AET4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PPM1J", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AET4", "locus": { "chromosome": "26", "start_pos": 3597474, "end_pos": 3605542, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027516", "url": "https://www.ensembl.org/id/ENSGALG00010027516" } ] } } ], "crossref": [ { "id": "A0A8V1AET4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AET4", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00143", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00143", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "419873", "url": "https://www.ncbi.nlm.nih.gov/gene/419873", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001932", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001932", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015655", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015655", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036457", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036457", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:419873", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419873", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RDHSMTG", "url": "https://omabrowser.org/oma/group/RDHSMTG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AET4", "url": "https://www.orthodb.org/?gene=A0A8V1AET4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13832", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13832", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13832:SF305", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13832:SF305", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00481", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00481", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_418000", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418000", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AET4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AET4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AET4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AET4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLLRVRSAVSHLVAGLGPGPGTQSPAEPRHGGGGGSGAGGEEGPRVAAFCRPAFLQLTPEELRRADDHTGRAVQSPRDGRRRLPWSTGYAEVINAGKSQHNEDQACCEVVFVERRPSPRGRLPCRDGSGEPDRGRKGFYFHYWALFDGHAGSGAAVMASKRLHLHICEQLRDLVDILQDPSPPPICLQHDAELSQAEDNGEVPSDALPRFHLEKAVSHESLVIGAIENAFKHMDEQIEQERTSQHISGGCCALAAVYLMGKFYVANAGDSRAIIIRNGEIIPMSREFTPETERQRLQFLAFLRPELLGKEFTHLEFPRRIQPKELGKKMLYRDQSMNGWAYKKIEEDDLKFPLIYGEGKKARVMATIGVTRGLGDHDLKVFSSNIHIKPFLSCFPEVRVYDLTQYEHCPDDVLVLGTDGLWDVTNDKEVASVVMEVLTSYEPNDPCRYTVVAQELVVRSRGVLKERGWRLPNDKLGSGDDISVFVIPLGGPGNYM", "length": 495, "header": "tr|A0A8V1AET4-1|A0A8V1AET4_CHICK Isoform 1 of Protein phosphatase, Mg2+/Mn2+ dependent 1J OS=Gallus gallus OX=9031 GN=PPM1J PE=4 SV=1 CANONICAL=A0A8V1AET4-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AET4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AET4/entry#A0A8V1AET4-1", "sequence": { "sequence": "MLLRVRSAVSHLVAGLGPGPGTQSPAEPRHGGGGGSGAGGEEGPRVAAFCRPAFLQLTPEELRRADDHTGRAVQSPRDGRRRLPWSTGYAEVINAGKSQHNEDQACCEVVFVERRPSPRGRLPCRDGSGEPDRGRKGFYFHYWALFDGHAGSGAAVMASKRLHLHICEQLRDLVDILQDPSPPPICLQHDAELSQAEDNGEVPSDALPRFHLEKAVSHESLVIGAIENAFKHMDEQIEQERTSQHISGGCCALAAVYLMGKFYVANAGDSRAIIIRNGEIIPMSREFTPETERQRLQFLAFLRPELLGKEFTHLEFPRRIQPKELGKKMLYRDQSMNGWAYKKIEEDDLKFPLIYGEGKKARVMATIGVTRGLGDHDLKVFSSNIHIKPFLSCFPEVRVYDLTQYEHCPDDVLVLGTDGLWDVTNDKEVASVVMEVLTSYEPNDPCRYTVVAQELVVRSRGVLKERGWRLPNDKLGSGDDISVFVIPLGGPGNYM", "length": 495, "header": "tr|A0A8V1AET4-1|A0A8V1AET4_CHICK Isoform 1 of Protein phosphatase, Mg2+/Mn2+ dependent 1J OS=Gallus gallus OX=9031 GN=PPM1J PE=4 SV=1 CANONICAL=A0A8V1AET4-1" }, "locus": { "chromosome": "26", "start_pos": 3605343, "end_pos": 3598889, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066651.1", "url": "https://www.ensembl.org/id/ENSGALT00010066651.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040809.1", "url": "https://www.ensembl.org/id/ENSGALP00010040809.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:419873", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419873", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1SBQ0-1", "protein_name": "Protein phosphatase, Mg2+/Mn2+ dependent 1J", "gene_name": "PPM1J", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLNRVRSAVAHLVSSGGGPPPRPKSPDLPNATSAPPAAPPEAPRSPPARAGSASAAPRKIAEARASFSRPTFLQLSPGGLRRADDHAGRAVQSPPDTGRRLPWSTGYAEVINAGKSRHNEDQACCEVVYVEGRRSVSGAPREPSRGQGLCFYYWGLFDGHAGGGAAEMASRLLHRHIREQLKDLVEILQDPSPPPLCLPSTPGAPGSSDSSHLVGPQPCWPLQKEVTHESLVVGAIENAFQLMDEQMARERRGHQVEGGCCALVVVYLLGKVYVANAGDSRAIIVRNGEIIPMSQEFTPETERQRLQLLGFLKPELLGGEFTHLEFPRRVQPKELGQRMLYRDQNMTGWAYKKIELEDLRFPLVCGEGKKARVMATIGVTRGLGDHNLRVCSSTLPIKPFLSCFPEVRVYDLTQYEHCPDDVLVLGTDGLWDVTSDCEVAATVDKVLSAYEPNDPSRYTALAQALVLGARGTPRDRGWRLPNNKLGSGDDISVFIIPLGGPGSYS", "length": 505 }, "evidence": [ { "id": "A0A8V1AET4", "url": "https://omabrowser.org/oma/group/A0A8V1AET4/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q149T7-1", "protein_name": "Protein phosphatase 1J", "gene_name": "Ppm1j", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLNRVRSAVAHLVSSGGTSSQRSKSPDLPNATSAPPAAQETPKSSREKPGNQVGAPQKTAETTVSFSRPTFLQLSPGGLRRADDHAGRAVQSPPDTGRRLPWSTGYAEVINAGKSRHNEDQACCEVVYVESRRSRSVTGVSREPSHNQGFCFYYWGLFDGHAGGGAAEMASRLLHRHIREQLKDLVEILKDPLPPPLCLPSTPGTPGAPSPSQLVSPQSCWSPQKEVTHDSLIVGAIENAFHLMDEQMARERRGHQVEGGCCALVVLYLLGKMYVANAGDSRAIIVRNGEIIPMSREFTPETERQRLQLLGFLKPELLGSEFTHLEFPRRVQPKELGQRMLYRDQNMTGWAYKKIEVEDLRFPLVCGEGKKARVMATIGVTRGLGDHNLKVCSSTLSIKPFLSCFPEVRVYDLTQYEHCPDDVLVLGTDGLWDVTNDSEVAATVDRVLSSYEPNDPSRYTALAQALVLGARGIPRDRGWRLPNNKLGSGDDISVFVIPLGGPGSSYS", "length": 507 }, "evidence": [ { "id": "A0A8V1AET4", "url": "https://omabrowser.org/oma/group/A0A8V1AET4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5JR12-1", "protein_name": "Protein phosphatase 1J", "gene_name": "PPM1J", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLNRVRSAVAHLVSSGGAPPPRPKSPDLPNAASAPPAAAPEAPRSPPAKAGSGSATPAKAVEARASFSRPTFLQLSPGGLRRADDHAGRAVQSPPDTGRRLPWSTGYAEVINAGKSRHNEDQACCEVVYVEGRRSVTGVPREPSRGQGLCFYYWGLFDGHAGGGAAEMASRLLHRHIREQLKDLVEILQDPSPPPLCLPTTPGTPDSSDPSHLLGPQSCWSSQKEVSHESLVVGAVENAFQLMDEQMARERRGHQVEGGCCALVVIYLLGKVYVANAGDSRAIIVRNGEIIPMSREFTPETERQRLQLLGFLKPELLGSEFTHLEFPRRVLPKELGQRMLYRDQNMTGWAYKKIELEDLRFPLVCGEGKKARVMATIGVTRGLGDHSLKVCSSTLPIKPFLSCFPEVRVYDLTQYEHCPDDVLVLGTDGLWDVTTDCEVAATVDRVLSAYEPNDHSRYTALAQALVLGARGTPRDRGWRLPNNKLGSGDDISVFVIPLGGPGSYS", "length": 505 }, "evidence": [ { "id": "A0A8V1AET4", "url": "https://omabrowser.org/oma/group/A0A8V1AET4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q641Y6-1", "protein_name": "Protein phosphatase 1J", "gene_name": "Ppm1j", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLNRVRSAVAHLVSSSGTSSQRSKSPDLPKAISPPPGALETPKSPGTKSGNEIPAPQKTAETPVSFSRPTFLQLSPGGLRRADDHVGRAVQSPPDTGRRLPWSTGYAEVINAGKSRHNEDQACCEVVYVESRRSITGVSREPSHNQGFSFYYWGLFDGHAGGGAAEMASRLLHRHIREQLKDLVEILQDPLPPPLCLPSTPGTPGVSSPSQLVSPQSWSPQKEVTHDSLVVGAIENAFQLMDEQMARERRGHLVEGGCCALVVVYLLGKMYVANAGDSRAIIVRNGEIIPMSREFTPETERQRLQLLGFLKPELLGSEFTHLEFPRRVQPKELGQRMLYRDQNMTGWAYKKIELEDLRFPLVCGEGKKARVMATIGVTRGLGDHNLKVCSSTLPIKPFLSCFPEVRVYDLTQYEHCPDDVLVLGTDGLWDVTNDSEVAATVDRVLSTYEPNDPSRYTALAQALVLGARGIPRDRGWRLPNNKLGSGDDISVFVIPLGGPGSSYS", "length": 504 }, "evidence": [ { "id": "A0A8V1AET4", "url": "https://omabrowser.org/oma/group/A0A8V1AET4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "[pyruvate dehydrogenase (acetyl-transferring)]-phosphatase activity", "id": "GO:0004741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004741", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AET4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AET4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AET4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AET4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AET4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AET4" }, { "id": "PS51746", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51746" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PPM-type phosphatase", "eco_id": "ECO_0000259", "start_pos": 86, "end_pos": 488, "start_aa": "Ser", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AET9-1", "uniprot_ac": "A0A8V1AET9", "uniprot_id": "A0A8V1AET9_CHICK", "mass": { "chemical_mass": 153590.0, "monoisotopic_mass": 153590.0 }, "refseq": { "ac": "XP_015150931", "name": "transmembrane protein 94 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015150931" }, "gene_names": [ { "name": "TMEM94", "type": "recommended", "evidence": [ { "id": "A0A8V1AET9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AET9" } ] }, { "name": "TMEM94", "type": "synonym", "evidence": [ { "id": "XP_015150931", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015150931" } ] } ], "protein_names": [ { "name": "Transmembrane protein 94", "type": "synonym", "evidence": [ { "id": "A0A8V1AET9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AET9/entry#names_and_taxonomy" } ] }, { "name": "transmembrane protein 94 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015150931", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015150931" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052549.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015150931.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015150931", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015150931" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AET9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AET9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TMEM94", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AET9", "locus": { "chromosome": "18", "start_pos": 11467878, "end_pos": 11420967, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029708", "url": "https://www.ensembl.org/id/ENSGALG00010029708" } ] } } ], "crossref": [ { "id": "422124", "url": "https://www.ncbi.nlm.nih.gov/gene/422124", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR023298", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023298", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039720", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039720", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:422124", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422124", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GCAMQTP", "url": "https://omabrowser.org/oma/group/GCAMQTP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AET9", "url": "https://www.orthodb.org/?gene=A0A8V1AET9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ALT7", "url": "https://www.orthodb.org/?gene=A0A8V1ALT7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1APW1", "url": "https://www.orthodb.org/?gene=A0A8V1APW1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13219", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13219", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13219:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13219:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "XP_015150931", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015150931", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AET9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AET9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AET9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AET9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALT7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALT7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALT7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALT7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1APW1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APW1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1APW1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APW1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLFKQPDLWITHQGKCHKDEMTSSLGLTTKKALAILRDQLTTLLEGHQKERKKVTSWKEAWRSSFLYHGNRCSCFHWPGASLMLLAVVLLLCCSGSQPQGNQGAEIVNALALFLLLLLDLFMVGRHERLKCKEVERRLQMIIDKINDTLGKEVKWPDSMYPDLHMPYAPSWSLHWAYRDGHLVNLPVSLLVEGDVIALRPGQESFASLRGIKDDEHIVLEPGDLFPPFSPPPSPRGEVKKGPQNPQLYRLFRVLKTPIIDNVRWCLEMALSRPVTALDNERFTVQSVMLKYAVPIVLAGFLITNAVRFIFKAPGVASWQHTLLQLQVNGVLPILPLLFPVLWILATAFGEARVLAQMSKASSTSLLAKFSEDTLSSYTEMVSSQEMIRCIWSHFLCVLKGKSPTLSFTSSLLHSLGSVTVLCCVDKQGILSWPNPSPETVLFFSGKVEPHHDSHEDLTDELSTRSFCHHEMDDEPHERDALLSDPLADTVHVTNEQEKNNWSSDPPKAPDAHAHRKPNSRSKHPSGSNVSFSKDTEGGEEEHTQVAGDTEVLACEAEDFVCDYHLEMLSLSQDQQNPSCIQFDDSNWQIHLNSLKPLGLNVLLNLCNATVTERLCRFSDHLCNIALQETHNAVLPVHVPWGLCELARLIGFTPGAKDLFKQENYLALYRLPSDEMVKETMLGKLSSITKRRPPLSHMINLFVKDTTTSTEQMFSHGTADIILEACTDFWDGTDIYPLSGSDRKKVLDFYQRACLSGYCSAFAYKPMHCALSSQLNGKCIELVQVPGQSAIFACCDLPGTTPIKQSSRRNSWSSDEGIGEVMEKEDCIQALSGQIFMGMVSSQYQARLDIVRLIDGLVNACIRFVYFSLEDELKSKVFAEKMGLETGWNCHISLTPNGDVPGSEIPPSSPSHAGSLHDDLHQVSRDDVEGLLLMEEEGHSDLISFQPTDSDIPSFLEDCNRAKLPRGIHQVRPHLQNIDNVPLLVPLFTDCTPETMCEMIKIMQEYGEVTCCLGSSANLRNSCLFLQSDISIALDPLYPSRCSWETFGYATSTTMPHASDELTPLQLSGQLNSLPCSMSFRQEESTSIIRLIEQARHATYGIRKCFLFLLQCQLTLVVIQFLSCLVQLPPILSTTDIVWLSCFCYPLLSISLLGKPPHSSIMTMATGKNLTSIPKKTQHYFLFCFLLKFSVTICSCLICFGFTLHESCKEVNTTSLNLTACPSIMLHSNSHGAPDWFGTFSNALLVAQKLTAGLIVLHTVFISITHVHRTKPLWKKSPLSNWWWTLTVAIVLLGQVAQTLLDLKLWENLSSPLTFKYISISPVSWLLGFLSLILVVIINEIVKLHEIRVRVRYQKRQKLQFETKLGMNSPF", "length": 1370, "header": "tr|A0A8V1AET9-1|A0A8V1AET9_CHICK Isoform 1 of Transmembrane protein 94 OS=Gallus gallus OX=9031 GN=TMEM94 PE=4 SV=1 CANONICAL=A0A8V1AET9-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AET9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AET9/entry#A0A8V1AET9-1", "sequence": { "sequence": "MLFKQPDLWITHQGKCHKDEMTSSLGLTTKKALAILRDQLTTLLEGHQKERKKVTSWKEAWRSSFLYHGNRCSCFHWPGASLMLLAVVLLLCCSGSQPQGNQGAEIVNALALFLLLLLDLFMVGRHERLKCKEVERRLQMIIDKINDTLGKEVKWPDSMYPDLHMPYAPSWSLHWAYRDGHLVNLPVSLLVEGDVIALRPGQESFASLRGIKDDEHIVLEPGDLFPPFSPPPSPRGEVKKGPQNPQLYRLFRVLKTPIIDNVRWCLEMALSRPVTALDNERFTVQSVMLKYAVPIVLAGFLITNAVRFIFKAPGVASWQHTLLQLQVNGVLPILPLLFPVLWILATAFGEARVLAQMSKASSTSLLAKFSEDTLSSYTEMVSSQEMIRCIWSHFLCVLKGKSPTLSFTSSLLHSLGSVTVLCCVDKQGILSWPNPSPETVLFFSGKVEPHHDSHEDLTDELSTRSFCHHEMDDEPHERDALLSDPLADTVHVTNEQEKNNWSSDPPKAPDAHAHRKPNSRSKHPSGSNVSFSKDTEGGEEEHTQVAGDTEVLACEAEDFVCDYHLEMLSLSQDQQNPSCIQFDDSNWQIHLNSLKPLGLNVLLNLCNATVTERLCRFSDHLCNIALQETHNAVLPVHVPWGLCELARLIGFTPGAKDLFKQENYLALYRLPSDEMVKETMLGKLSSITKRRPPLSHMINLFVKDTTTSTEQMFSHGTADIILEACTDFWDGTDIYPLSGSDRKKVLDFYQRACLSGYCSAFAYKPMHCALSSQLNGKCIELVQVPGQSAIFACCDLPGTTPIKQSSRRNSWSSDEGIGEVMEKEDCIQALSGQIFMGMVSSQYQARLDIVRLIDGLVNACIRFVYFSLEDELKSKVFAEKMGLETGWNCHISLTPNGDVPGSEIPPSSPSHAGSLHDDLHQVSRDDVEGLLLMEEEGHSDLISFQPTDSDIPSFLEDCNRAKLPRGIHQVRPHLQNIDNVPLLVPLFTDCTPETMCEMIKIMQEYGEVTCCLGSSANLRNSCLFLQSDISIALDPLYPSRCSWETFGYATSTTMPHASDELTPLQLSGQLNSLPCSMSFRQEESTSIIRLIEQARHATYGIRKCFLFLLQCQLTLVVIQFLSCLVQLPPILSTTDIVWLSCFCYPLLSISLLGKPPHSSIMTMATGKNLTSIPKKTQHYFLFCFLLKFSVTICSCLICFGFTLHESCKEVNTTSLNLTACPSIMLHSNSHGAPDWFGTFSNALLVAQKLTAGLIVLHTVFISITHVHRTKPLWKKSPLSNWWWTLTVAIVLLGQVAQTLLDLKLWENLSSPLTFKYISISPVSWLLGFLSLILVVIINEIVKLHEIRVRVRYQKRQKLQFETKLGMNSPF", "length": 1370, "header": "tr|A0A8V1AET9-1|A0A8V1AET9_CHICK Isoform 1 of Transmembrane protein 94 OS=Gallus gallus OX=9031 GN=TMEM94 PE=4 SV=1 CANONICAL=A0A8V1AET9-1" }, "locus": { "chromosome": "18", "start_pos": 11465367, "end_pos": 11431484, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071858.1", "url": "https://www.ensembl.org/id/ENSGALT00010071858.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044548.1", "url": "https://www.ensembl.org/id/ENSGALP00010044548.1" } ] } }, { "isoform_ac": "A0A8V1ALT7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AET9/entry#A0A8V1ALT7-1", "sequence": { "sequence": "MLLAVVLLLCCSGSQPQGNQGAEIVNALALFLLLLLDLFMVGRHERLKCKEVERRLQMIIDKINDTLGKEVKWPDSMYPDLHMPYAPSWSLHWAYRDGHLVNLPVSLLVEGDVIALRPGQESFASLRGIKDDEHIVLEPGDLFPPFSPPPSPRGEVKKGPQNPQLYRLFRVLKTPIIDNVRWCLEMALSRPVTALDNERFTVQSVMLKYAVPIVLAGFLITNAVRFIFKAPGVASWQHTLLQLQVNGVLPILPLLFPVLWILATAFGEARVLAQMSKASSTSLEMIRCIWSHFLCVLKGKSPTLSFTSSLLHSLGSVTVLCCVDKQGILSWPNPSPETVLFFSGKVEPHHDSHEDLTDELSTRSFCHHEMDDEPHERDALLSDPLADTVHVTNEQEKNNWSSDPPKAPDAHAHRKPNSRSKHPSGSNVSFSKDTEGGEEEHTQVAGDTEVLACEAEDFVCDYHLEMLSLSQDQQNPSCIQFDDSNWQIHLNSLKPLGLNVLLNLCNATVTERLCRFSDHLCNIALQETHNAVLPVHVPWGLCELARLIGFTPGAKDLFKQENYLALYRLPSDEMVKETMLGKLSSITKRRPPLSHMINLFVKDTTTSTEQMFSHGTADIILEACTDFWDGTDIYPLSGSDRKKVLDFYQRACLSGYCSAFAYKPMHCALSSQLNGKCIELVQVPGQSAIFACCDLPGTTPIKQSSRRNSWSSDEGIGEVMEKEDCIQALSGQIFMGMVSSQYQARLDIVRLIDGLVNACIRFVYFSLEDELKSKVFAEKMGLETGWNCHISLTPNGDVPGSEIPPSSPSHAGSLHDDLHQVSRDDVEGLLLMEEEGHSDLISFQPTDSDIPSFLEDCNRAKLPRGIHQVRPHLQNIDNVPLLVPLFTDCTPETMCEMIKIMQEYGEVTCCLGSSANLRNSCLFLQSDISIALDPLYPSRCSWETFGYATSTTMPHASDELTPLQLSGQLNSLPCSMSFRQEESTSIIRLIEQARHATYGIRKCFLFLLQCQLTLVVIQFLSCLVQLPPILSTTDIVWLSCFCYPLLSISLLGKPPHSSIMTMATGKNLTSIPKKTQHYFLFCFLLKFSVTICSCLICFGFTLHESCKEVNTTSLNLTACPSIMLHSNSHGAPDWFGTFSNALLVAQKLTAGLIVLHTVFISITHVHRTKPLWKKSPLSNWWWTLTVAIVLLGQVAQTLLDLKLWENLSSPLTFKYISISPVSWLLGFLSLILVVIINEIVKLHEIRVRVRYQKRQKLQFETKLGMNSPF", "length": 1269, "header": "tr|A0A8V1ALT7-1|A0A8V1AET9_CHICK Computationally mapped isoform of Transmembrane protein 94 OS=Gallus gallus OX=9031 GN=TMEM94 PE=4 SV=1 CANONICAL=A0A8V1AET9-1" }, "locus": { "chromosome": "18", "start_pos": 11465367, "end_pos": 11437976, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071857.1", "url": "https://www.ensembl.org/id/ENSGALT00010071857.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044547.1", "url": "https://www.ensembl.org/id/ENSGALP00010044547.1" } ] } }, { "isoform_ac": "A0A8V1APW1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AET9/entry#A0A8V1APW1-1", "sequence": { "sequence": "MDRKEKCQDEMTSSLGLTTKKALAILRDQLTTLLEGHQKERKKVTSWKEAWRSSFLYHGNRCSCFHWPGASLMLLAVVLLLCCSGSQPQGNQGAEIVNALALFLLLLLDLFMVGRHERLKCKEVERRLQMIIDKINDTLGKEVKWPDSMYPDLHMPYAPSWSLHWAYRDGHLVNLPVSLLVEGDVIALRPGQESFASLRGIKDDEHIVLEPGDLFPPFSPPPSPRGEVKKGPQNPQLYRLFRVLKTPIIDNVRWCLEMALSRPVTALDNERFTVQSVMLKYAVPIVLAGFLITNAVRFIFKAPGVASWQHTLLQLQVNGVLPILPLLFPVLWILATAFGEARVLAQMSKASSTSLLAKFSEDTLSSYTEMVSSQEMIRCIWSHFLCVLKGKSPTLSFTSSLLHSLGSVTVLCCVDKQGILSWPNPSPETVLFFSGKVEPHHDSHEDLTDELSTRSFCHHEMDDEPHERDALLSDPLADTVHVTNEQEKNNWSSDPPKAPDAHAHRKPNSRSKHPSGSNVSFSKDTEGGEEEHTQVAGDTEVLACEAEDFVCDYHLEMLSLSQDQQNPSCIQFDDSNWQIHLNSLKPLGLNVLLNLCNATVTERLCRFSDHLCNIALQETHNAVLPVHVPWGLCELARLIGFTPGAKDLFKQENYLALYRLPSDEMVKETMLGKLSSITKRRPPLSHMINLFVKDTTTSTEQMFSHGTADIILEACTDFWDGTDIYPLSGSDRKKVLDFYQRACLSGYCSAFAYKPMHCALSSQLNGKCIELVQVPGQSAIFACCDLPGTTPIKQSSRRNSWSSDEGIGEVMEKEDCIQALSGQIFMGMVSSQYQARLDIVRLIDGLVNACIRFVYFSLEDELKSKVFAEKMGLETGWNCHISLTPNGDVPGSEIPPSSPSHAGSLHDDLHQVSRDDVEGLLLMEEEGHSDLISFQPTDSDIPSFLEDCNRAKLPRGIHQVRPHLQNIDNVPLLVPLFTDCTPETMCEMIKIMQEYGEVTCCLGSSANLRNSCLFLQSDISIALDPLYPSRCSWETFGYATSTTMPHASDELTPLQLSGQLNSLPCSMSFRQEESTSIIRLIEQARHATYGIRKCFLFLLQCQLTLVVIQFLSCLVQLPPILSTTDIVWLSCFCYPLLSISLLGKPPHSSIMTMATGKNLTSIPKKTQHYFLFCFLLKFSVTICSCLICFGFTLHESCKEVNTTSLNLTACPSIMLHSNSHGAPDWFGTFSNALLVAQKLTAGLIVLHTVFISITHVHRTKPLWKKSPLSNWWWTLTVAIVLLGQVAQTLLDLKLWENLSSPLTFKYISISPVSWLLGFLSLILVVIINEIVKLHEIRVRVRYQKRQKLQFETKLGMNSPF", "length": 1360, "header": "tr|A0A8V1APW1-1|A0A8V1AET9_CHICK Computationally mapped isoform of Transmembrane protein 94 OS=Gallus gallus OX=9031 GN=TMEM94 PE=4 SV=1 CANONICAL=A0A8V1AET9-1" }, "locus": { "chromosome": "18", "start_pos": 11465367, "end_pos": 11427790, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071859.1", "url": "https://www.ensembl.org/id/ENSGALT00010071859.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044549.1", "url": "https://www.ensembl.org/id/ENSGALP00010044549.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:422124", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422124", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6AA40-1", "protein_name": "Transmembrane protein 94", "gene_name": "Tmem94", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAAPGEDAGEEDRPRGPGCCDCDTLTGVCPCWGGSFLPGVTALIWACLKYPGPMDLKEKHLGEPPSALGLTTGKALSVLKEQLEAVLEKHLKERKKRLTWKEAWRSSFLHLSNRRSCFHWPGASLMLLAVLLLLCCSGGQPAGSRGVELVNASALFLLLLLNLILIGRQDRLKRQEVERRLRGIIDQIQDALRDGKEIKWPNSMYPDLHMPFAPSWSLHWAYRDGHLVNLPVSLLVEGDIIALRPGQESFASLRGIKDDEHIVLEPGDLFPPFSPPPSPRGEVKKGPQNPQQYRLFRVLETPVIDSIRWCLDTALSRPVTALDNERFTVQSVMLHYAVPVVLAGFLITNALRFMFKAPGVTSWQYTLLQLQVNGMLPILPLLFPVLWVLATACGEARVLAQMSKASPSSLLAKFSEDTLSSYTEAVSSQEMLRCIWGHFLRVIQGTSPTLSHSASLLHSLGSVTVLCCVDKQGILSWPNPSPETVLFFSGKVEPPHSSHEDLTDDLSTRSFCHPEVEEEPHERDALLAGSLNNTLHLSNEQERGDWPGDGPKPSEPYSHHKGHGRSKHPSGSNVSFSRDTEGGEEEPSKAQPGTEGDPYEAEDFVCDYHLEMLSLSQDQQNPSCIQFDDSNWQLHLTSLKPLGLNVLLNLCNASVTERLCRFSDHLCNIALQESHSAVLPVHVPWGLCELARLIGFTPGAKELFKQENHLALYRLPSAETVKETSLGRPSCVTKRRPPLSHMISLFIKDTATSTEQMLSHGSADVVVEACTDFWDGADIYPLSGSDRKKVLDFYQRACLSGYCSAFAYKPMNCTLSSQLNGKCIELVQVPGQNSISTLCELPSTVPIKPNIRRSSWSSDEGIGEVLEKEDCMQALSGQIFMGMVSSQYQARLDIVRLIDGLVNACIRFVYFSLEDELRSKVFAEKMGLETGWNCHISLTPNGDMPGSEIPPSSPSHAGSLHDDLNQVSRDDAEGLLLLEEEGHSDLISFQPTDSDIPSFLEDCNRAKLPRGIHQVRPHLQNIDNVPLLVPLFTDCTPDTMCEMMKIMQEYGEVTCCLGSSANLRNSCLFLQSDVSIALDPLYPSRCSWESFGYATSTTMAQASDGLSPLQLSGQLNSLPCSLTFRQEETISIIRLIEQARHATYGIRKCFLFLLQCQLTLVVIQFLSCLVQLPPLLSTTDILWLSCFCYPLLSISLLGKPPHSSVMSMATGKNLQSIPKKTQHYFLLCFLLKFSLTISSCLACFGFTLQSFCDSARARNLTNCSSVMLCSNDDRAPAWFEDFANGLLSAQKLTAALIVLHTVFISITHVHRTKPLWRKSPLTNLWWAVTVPVVLLGQVVQTVVDLQLWTHRDSPVHFGLEDVPLLTWLLGCLSLVLVVVTNEIVKLHEIRVRVRYQKRQKLQFETKLGMNSPF", "length": 1414 }, "evidence": [ { "id": "A0A8V1AET9", "url": "https://omabrowser.org/oma/group/A0A8V1AET9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8M9QJ95-1", "protein_name": "Transmembrane protein 94 isoform X1", "gene_name": "tmem94", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MELQDKKQEEETATPLGLSTAQALCTLRDQLSNLLGQHQKFSRRRPTIQELWAKSFLHHGDRHSCFHWPGAVLTLVVVVGLLSCHGSQPEGSQGIELVNAGALFLLLLLNLFLIGRQQRLRISEMVRRLKSIISQLNDYLERSAGHPIRWAPSLYPDLYTPTSPSWSLHWTFRDEQLVNLPVSLLVEGDVIALRPGQEAFASLRGIKDDEHIVLEPGDLFPPFSPPPSPRGNERRGPHSPQQYRLFRVVRTPILDSVRNSLDLALSRPITALDNERFTVQSIIAKFACPAVLVAFFSMNTIRYFCDTPGLTPGPFNFLQLQMMGVLPILPLLFPVMWVLVNAYGEARVLAESSRNSPTGLLAKFSEDTLSSYTEVVSSQEMLRCVWRHLVSVLKGESQTLCYTSSLLHTLGSVTVLCCVDKQGILSWPNPSPETVLFFSGRVEPPHDSQDDLRDDLSVNSLCRTEGEEDRDEPQEGEALLCLPAFEPPLHMAEQEPSETSHDTARSSDTQRQRRGPQTTRSKHPSGSNVSFSHDTEGGENDFVQQCGLGDDLCEADDFVCDYHLEMLSLSQDQQNPVSIQFDDSGWQNHLSSLKPLGLNILLNLCNATVTQQLCRFSDHLSNLALQECHGAVLPVHVPWGLCELSRLIGFTPGARELFKHENHLALYQLPSGEKAKESAPRRLHHFTKRQPPISHLISLFVRDNTTNNVQMLSHGSADLILEACTDFWDGADIYPLSGSDRKKVLDFYQRACLSGYCSAFAYKPMQVTLSGQLNGKCVELAPGPALFSGVELPSTTPIKHGSRRNSWSSDEGIGEGLEKEDCVQALSGQIFMGMVSSQFQARLDTVRLIENLVGACIRFVYFSMEDELRSKVFAEKMGLETGWNCHISLTPNGDGHCDGAPSSPSQAGSLHDELLQDSRDDAEGPLLPEDQSDLASFQPTDSDVPSFLEDCNRAKLPRGIHQVRPHLKNIDNVPLLVPLFTDCTPETMCEMMKIMQENREVTCCLGSSANFRNSCLFLQSDISISLDPLYPSRCSWETFGYAAVCGLNEECDELSPLGLSASLNSLACSVSFHQGESVSMVKLIEQARHTTYGIRKCFLFLLQCQLTLVIIQFLACLIQLPPPMNITDILWLSCFCYPLLSVSLLGKPPDSSVMTVATGKNLDSIPRKTQHYFLGWFLLKFGLTVLAYLVGFGFSLQEVCSRAANFTKTDNSTINCSHILTSSSQGAPEWFGELSNGLLLIQKIMAGFLALHTVVISFSYVHRSQPLWRRNPFSNTWWCLTVPVVLLGQVVQAVIDYHLWRNRRTEVVFTLHHIPLMVWLLVSLSIVLVVLINEAVKLHEIRVRVRYQKRQKLQFETKLGMNSPF", "length": 1365 }, "evidence": [ { "id": "A0A8V1AET9", "url": "https://omabrowser.org/oma/group/A0A8V1AET9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q12767-1", "protein_name": "Transmembrane protein 94", "gene_name": "TMEM94", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDLKEKHLGEPPSALGLSTRKALSVLKEQLEAVLEGHLRERKKCLTWKEVWRSSFLHHSNRCSCFHWPGASLMLLAVLLLLGCCGGQPAGSRGVGLVNASALFLLLLLNLVLIGRQDRLKRREVERRLRGIIDQIQDALRDGREIQWPSAMYPDLHMPFAPSWSLHWAYRDGHLVNLPVSLLVEGDIIALRPGQESFASLRGIKDDEHIVLEPGDLFPPFSPPPSPRGEVERGPQSPQQHRLFRVLETPVIDNIRWCLDMALSRPVTALDNERFTVQSVMLHYAVPVVLAGFLITNALRFIFSAPGVTSWQYTLLQLQVNGVLPILPLLFPVLWVLATACGEARVLAQMSKASPSSLLAKFSEDTLSSYTEAVSSQEMLRCIWGHFLRVLGGTSPTLSHSSSLLHSLGSVTVLCCVDKQGILSWPNPSPETVLFFSGKVEPPHSSHEDLTDGLSTRSFCHPEPHERDALLAGSLNNTLHLSNEQERGDWPGEAPKPPEPYSHHKAHGRSKHPSGSNVSFSRDTEGGEEEPSKTQPGMESDPYEAEDFVCDYHLEMLSLSQDQQNPSCIQFDDSNWQLHLTSLKPLGLNVLLNLCDASVTERLCRFSDHLCNIALQESHSAVLPVHVPWGLCELARLIGFTPGAKELFKQENHLALYRLPSAETMKETSLGRLSCVTKRRPPLSHMISLFIKDTTTSTEQMLSHGTADVVLEACTDFWDGADIYPLSGSDRKKVLDFYQRACLSGYCSAFAYKPMNCALSSQLNGKCIELVQVPGQSSIFTMCELPSTIPIKQNARRSSWSSDEGIGEVLEKEDCMQALSGQIFMGMVSSQYQARLDIVRLIDGLVNACIRFVYFSLEDELKSKVFAEKMGLETGWNCHISLTPNGDMPGSEIPPSSPSHAGSLHDDLNQVSRDDAEGLLLMEEEGHSDLISFQPTDSDIPSFLEDSNRAKLPRGIHQVRPHLQNIDNVPLLVPLFTDCTPETMCEMIKIMQEYGEVTCCLGSSANLRNSCLFLQSDISIALDPLYPSRCSWETFGYATSISMAQASDGLSPLQLSGQLNSLPCSLTFRQEETISIIRLIEQARHATYGIRKCFLFLLQCQLTLVVIQFLSCLVQLPPLLSTTDILWLSCFCYPLLSISLLGKPPHSSIMSMATGKNLQSIPKKTQHYFLLCFLLKFSLTISSCLICFGFTLQSFCDSSRDRNLTNCSSVMLPSNDDRAPAWFEDFANGLLSAQKLTAALIVLHTVFISITHVHRTKPLWRKSPLTNLWWAVTVPVVLLGQVVQTAVDLQLWTHRDSHVHFGLEDVPLLTWLLGCLSLVLVVVTNEIVKLHEIRVRVRYQKRQKLQFETKLGMNSPF", "length": 1356 }, "evidence": [ { "id": "A0A8V1AET9", "url": "https://omabrowser.org/oma/group/A0A8V1AET9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q7TSH8-1", "protein_name": "Transmembrane protein 94", "gene_name": "Tmem94", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDLREKHLGEPPLALGLSTRKALSVLKEQLEAVLEKHLKERKKSLTWKEAWRSSFLHLSNRCSCFHWPGASLMLLAVLLLLCCCGGQPAGSQGVELVNASALFLLLLLNLVLIGRQDRLKRREVERRLRGIIDQIQDALRDGKEIKWPNSMYPDLHMPFAPSWSLHWAYRDGHLVNLPVSLLVEGDIIALRPGQESFASLRGIKDDEHIVLEPGDLFPPFSPPPSPRGEVKRGPQNPQQHRLFRVLETPVIDNIRWCLDTALSRPVTALDNERFTVQSVMLHYAVPVVLAGFLITNALRFMFKAPGVTSWQYTLLQLQVNGMLPILPLLFPVLWVLATACGEARVLAQMSKASPSSLLAKFSEDTLSSYTEAVSSQEMLRCIWGHFLRVIQGTSPTLSHSASLLHSLGSVTVLCCVDKQGILSWPNPSPETVLFFSGKVEPPHSSHEDLTDDLSTRSFCHPEVEEEPHEHDALLAGSLNNTLHLSNEQERSDWLADGPKPSEPYPHHKGHGRSKHPSGSNVSFSRDTEGGEEEPSKAQPGTEGDPYEAEDFVCDYHLEMLSLSQDQQNPSCIQFDDSNWQSHLTSLKPLGLNVLLNLCNASVTERLCRFSDHLCNIALQESHSAVLPVHVPWGLCELARLIGFTPGAKELFKQENHLALYRLPSAETLKETSLGRPSCVTKRRPPLSHMISLFIKDTATSTEQMLSHGSADVVVEACTDFWDGADIYPLSGSDRKKVLDFYQRACLSGYCSAFAYKPMNCTLSSQLNGKCIELVQVPGQNSIFTMCELPSTIPIKPNNRRSSWSSDEGIGEVLEKEDCMQALSGQIFMGMVSSQYQARLDIVRLIDGLVNACIRFVYFSLEDELRSKVFAEKMGLETGWNCHISLTPNGDMPGSEIPPSSPSHAGSLHDDLNQVSRDDAEGLLLLEEEGHSDLISFQPTDSDIPSFLEDCNRAKLPRGIHQVRPHLQNIDNVPLLVPLFTDCTPDTMCEMIKIMQEYGEVTCCLGSSANLRNSCLFLQSDVSIALDPLYPSRCSWETFGYATSTTMAQASDGLSPLQLSGQLNSLPCSLTFRQEESISIIRLIEQARHATYGIRKCFLFLLQCQLTLVVIQFLSCLVQLPPLLSTTDILWLSCFCYPLLSISLLGKPPHSSIMSMATGKNLQSIPKKTQHYFLLCFLLKFSLTISSCLVCFGFTLQSFCDSARARNLTNCSSVMLCSNDDRAPAWFEDFANGLLSAQKLTAALIVLHTVFISITHVHRTKPLWRKSPLTNLWWAVTVPVVLLGQVVQTVVDLQLWTHRDSRVHFGLEDVPLLTWLLGCLSLVLVVVTNEIVKLHEIRVRVRYQKRQKLQFETKLGMNSPF", "length": 1360 }, "evidence": [ { "id": "A0A8V1AET9", "url": "https://omabrowser.org/oma/group/A0A8V1AET9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VQZ1-1", "protein_name": "Lethal (2) k05819, isoform A", "gene_name": "l(2)k05819", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MAAKRAESPEKRASPEPTLRGLTTKVALRRLHEEIEKRVQLEHERQYGAESPYRKLRAAFVKRYDSPLGWLSIGSSLLASGALLATGMLWPALCLLAILSLDLFVVVRENNLRRTEIFRKARHAISEIKLAEQHFSDDWQQSNYPHLSNPMSPCVSLQWTYRDGKIVNLPWALLVRGDYIVLRPGHISPGPCHELETNKFFAANEIYGAAPHGDPPVKPVARPPLPNLVCCLESTPYLDNLTVCLKNSLKRPPTIYNQQRYLLVTKYIQQWGFISALVITLISGLLRLHGYGLPTDEKHNWRFVLVESSAAAIVPLLPLIFPLMWISMNLWGIARLQCFLKTPQAALEKSTSKSFEEDLDTPSYDYQNMSMLRSSVLRIWMQLWRGDSELLPRSANLVQVLGSISALCCVDKKGILSWPNPTAEKVFFLHNTDEEAREDGAGSQSSSQSESDDVPVVDEDHKERGIVAEVLDLTHDQHCPFRLEFDDHEWKAHIKSLKPLGLAILLNTCSPLTHEHYAQFCGHVTAVAMLDKDLVPVTNRYAYALIESSKSFLHGRCLCELAKQIGFTDHATDRFALEGQLASYRHLQPDVVRRDIRFARQLQLSSKVKVPFPHSLSVVMRENPGGYLSLFTQGTADIILDCCDDFWDGIDLRPLSAQDRKRALDFYQRSALTSYCTAFAYRPLRHGIHGALSGPQRSGGDCLYLELPPESKLRMQHVDKTHCDFQGGHHVKLSHSISTDSLLFSENKDEECNDVEGCFEMQCHQVFIGMVTMQYQAQNDIVRLVEHLEQACIRFVHFSKENELRSRVFSEKMGLESGWNCHISLLSEPEPDSEKERISAKPKEFPENIGKPQATTSTTATTTTTDHENNHHPSAKVMYISPPAPAPATASVSESISAAKTTEIVGDGPEISYLLGPPNNLESSKTLSSSAPGAISNPDENPLNALNSGDSHSPDSEGSKESSQDSCTKNNPPGDSELEAETEANKHKQRHSLDSAMDENCRSLSTLTESTDQSAPINFDMSNRAKLPRGIENIRPHLEQVDNVPLQVSLFTDCSAEATRQMLDIMQSYGEIVVCLGSSASNANADIFLQADCSIAVEPLYPQVCQDVDAYTEANIQNNKLLWQRHSGKSKGNDDEELLEGGLHGCAMQSPAHTISPLYLSRLLNSLPCSIAVCRDDPLSLVAIIELSRRFSLGLWNCIQYWACCAGSISILNVLCACLSQPPLVTPLLGIYLMCVPVPLIAISLAHIDVDPKIMNRATSKKQTDYDSRAFAFVMWCYGCKFIVLVVSLLVSYWMLLPNTQLNPAEPATEEPVLEIDDDDDPEFYQFLYIARSSALLGIILHFVFISVTFVHRDHALWQRNPFTNRIWAFTCLFLVLIHGIICFVQLLLEDFWVQLPNQWLALLILFGGSLLSMLVSELAKFQENKVNARYQRRARLDFGTKLGMNSPF", "length": 1449 }, "evidence": [ { "id": "A0A8V1AET9", "url": "https://omabrowser.org/oma/group/A0A8V1AET9/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AET9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AET9" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AET9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AET9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "P-type magnesium transporter activity", "id": "GO:0015444", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015444", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AET9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AET9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "magnesium ion transport from cytosol to endoplasmic reticulum", "id": "GO:0160176", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160176", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AET9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AET9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1168, "end_pos": 1170, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1211, "end_pos": 1213, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1216, "end_pos": 1218, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1307, "end_pos": 1309, "annotation": "n_glycosylation_sequon" }, { "start_pos": 146, "end_pos": 148, "annotation": "n_glycosylation_sequon" }, { "start_pos": 500, "end_pos": 502, "annotation": "n_glycosylation_sequon" }, { "start_pos": 528, "end_pos": 530, "annotation": "n_glycosylation_sequon" }, { "start_pos": 607, "end_pos": 609, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1168, "end_pos": 1170 }, { "start_pos": 1211, "end_pos": 1213 }, { "start_pos": 1216, "end_pos": 1218 }, { "start_pos": 1307, "end_pos": 1309 }, { "start_pos": 146, "end_pos": 148 }, { "start_pos": 500, "end_pos": 502 }, { "start_pos": 528, "end_pos": 530 }, { "start_pos": 607, "end_pos": 609 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AEU3-1", "uniprot_ac": "A0A8V1AEU3", "uniprot_id": "A0A8V1AEU3_CHICK", "mass": { "chemical_mass": 12363.0, "monoisotopic_mass": 12363.0 }, "refseq": {}, "gene_names": [ { "name": "APOA2", "type": "recommended", "evidence": [ { "id": "A0A8V1AEU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEU3" } ] } ], "protein_names": [ { "name": "Apolipoprotein A2", "type": "synonym", "evidence": [ { "id": "A0A8V1AEU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEU3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEU3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEU3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "APOA2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEU3", "locus": {} } ], "crossref": [ { "id": "A0A8V1AEU3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AEU3", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR006801", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006801", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036172", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036172", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AEU3", "url": "https://www.orthodb.org/?gene=A0A8V1AEU3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PF04711", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04711", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1AEU3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEU3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AEU3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEU3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKRLWVAALLLLCVCHAGAVPAHQSEPQSEDPQETPPDTTTLLSRHFQTLSDFFTKELPQRLRADEIQQQAKYVWEVQLRPLAQELRTNVLGLFSSFLDLGKTGGMEKD", "length": 109, "header": "tr|A0A8V1AEU3-1|A0A8V1AEU3_CHICK Isoform 1 of Apolipoprotein A2 OS=Gallus gallus OX=9031 GN=APOA2 PE=4 SV=1 CANONICAL=A0A8V1AEU3-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AEU3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEU3/entry#A0A8V1AEU3-1", "sequence": { "sequence": "MKRLWVAALLLLCVCHAGAVPAHQSEPQSEDPQETPPDTTTLLSRHFQTLSDFFTKELPQRLRADEIQQQAKYVWEVQLRPLAQELRTNVLGLFSSFLDLGKTGGMEKD", "length": 109, "header": "tr|A0A8V1AEU3-1|A0A8V1AEU3_CHICK Isoform 1 of Apolipoprotein A2 OS=Gallus gallus OX=9031 GN=APOA2 PE=4 SV=1 CANONICAL=A0A8V1AEU3-1" }, "locus": { "chromosome": "25", "start_pos": 2499390, "end_pos": 2498977, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066672.1", "url": "https://www.ensembl.org/id/ENSGALT00010066672.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040819.1", "url": "https://www.ensembl.org/id/ENSGALP00010040819.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEU3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEU3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "lipid transport", "id": "GO:0006869", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006869", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEU3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEU3" } ], "pmid": "" }, { "name": "lipoprotein metabolic process", "id": "GO:0042157", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042157", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEU3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEU3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "lipid binding", "id": "GO:0008289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008289", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEU3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEU3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AEU9-1", "uniprot_ac": "A0A8V1AEU9", "uniprot_id": "A0A8V1AEU9_CHICK", "mass": { "chemical_mass": 164980.0, "monoisotopic_mass": 164980.0 }, "refseq": { "ac": "XP_024997551", "name": "caskin-2 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024997551" }, "gene_names": [ { "name": "CASKIN2", "type": "recommended", "evidence": [ { "id": "A0A8V1AEU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEU9" } ] }, { "name": "CASKIN2", "type": "synonym", "evidence": [ { "id": "XP_024997551", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024997551" } ] } ], "protein_names": [ { "name": "Caskin-2", "type": "recommended", "evidence": [ { "id": "A0A8V1AEU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEU9/entry#names_and_taxonomy" } ] }, { "name": "caskin-2 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_024997551", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024997551" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052549.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_024997551", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024997551" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEU9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEU9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CASKIN2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEU9", "locus": { "chromosome": "18", "start_pos": 11468592, "end_pos": 11496921, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029711", "url": "https://www.ensembl.org/id/ENSGALG00010029711" } ] } } ], "crossref": [ { "id": "ENSGALG00000008034", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000008034", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd09497", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09497", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd09498", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09498", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12063", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12063", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "422125", "url": "https://www.ncbi.nlm.nih.gov/gene/422125", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001660", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001660", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013761", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013761", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032117", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032117", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032232", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032232", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033635", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033635", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035497", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035497", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035498", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035498", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035499", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035499", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036028", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036028", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:422125", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422125", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1AEU9", "url": "https://www.orthodb.org/?gene=A0A8V1AEU9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1APW4", "url": "https://www.orthodb.org/?gene=A0A8V1APW4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1APW6", "url": "https://www.orthodb.org/?gene=A0A8V1APW6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1C2D3", "url": "https://www.orthodb.org/?gene=E1C2D3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24174", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24174", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24174:SF18", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24174:SF18", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00023", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00023", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00536", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00536", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07653", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07653", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12796", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12796", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16600", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16600", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16632", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16632", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16907", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16907", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_024997551", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024997551", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AEU9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEU9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AEU9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEU9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1APW4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APW4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1APW4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APW4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1APW6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APW6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1APW6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APW6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C2D3", "url": "https://www.uniprot.org/uniprotkb/E1C2D3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C2D3-1", "url": "https://www.uniprot.org/uniprotkb/E1C2D3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGREQDLIQAVKNGDIPGVQKLVAKIKASKSKLLGSAKRLNVNYQDADGFSALHHAALGGSLDLISLLLEAQATVDIKDSNGMRPLHYAAWQGRVEPVRVLLRAAASVNMASLDGQIPLHLSAQYGHYEVSEMLLQHQSNPCLINKAKKTPLDLACEFGRLKVAQLLLNSHLCVALLEGQSKDVTDPNYTTPLHLAAKNGHKEIIRQLLKAGIEINKQTKTGTALHEAALYGKTEVVRLLLEGGVDVNIRNTYNQTALDIVNQFTTSHASKDIKQLLREASGILKVRALKDFWNLHDPTALNVRAGDIITVLEQHPDGRWKGHIHDIQKGTDRVGYFPPSIAEVISKRIGMILPRMAPTHQHQGTPGALMALPDCSPPRLQHLPDECPQQAAPGIPPSYGHLTLTWTAPGPDSSAGDRNSVGSEGSIGSIRSAGSGQSTEGTNGQNTNIVIENTRPLPSTGDDLQQHLLGSEPLNEQINSTTGPPGYQTPSSCTPGDKVFSHQFLRPEQLLEGKDAEAIYNWLSEFQLESYTVNFLSAGYDVPTISRMTPEDLTAIGVTKPGHRKKISTEIGQLSIAEWLPNYIPADLMDWLSAIGLPQYHKKLVNNGYDSITIVTDLTWEDLQEIGINKLGHQKKIMLAVKKLRDLRKSLSQAEATLTRHKVPGALHIVTIESLENGECQSPNTPKMTTFQDSELSYELQTAMSNSCHETLSIKNSQGMSQSQESIGVRSRGSGHSQDNVLSWHLSSPSQESLGSGESSSSSSGQSCMPPHSKESLASLPRQPSPEPYGKLTSPEGLNSFTNGSGGSPLKERNLPEGTDQYAQLTAQKGAGPVGTLMVTPSTPPQTPSMATAPYVFMYPHVSLKSPRAPSSQGAEQPKTLAHSYPSFSSGQKNSLQTSAPKAFSYLHSQCSPAELLEAATAPNAWQTGEQHKGGESSKNKKRSHSLNRYALSDGEHEEEEGMPTSTLGSYATLTRRPGRSQMPRACLQTEAKVTRSQSFAIRAKRKGPPPPPPKRLSSVSSTLTTEVDSEQLPDPERQSSVPQDAADMGASPGDSGCSRTVRSLVATLEETPGLNPPKPLLAPKPLHVAQDSLSKAAVDDRSHNSCDPSSTALSDSGQDPFDSSKPRRRTLSEPSTPMTEAVQGRQEDACSDTEEEAKPEVSSSSQNSSSECIPFAEEGNLTIKQRPKPAGHPKADAAVQDTEPSSQPAESTCSDGKELAVSAVTRELPMLEFNLTESDTVKRRPRFKEREPLQAVLKAFSMAGQAEVGASSAPQYAQAQAVSILGPTTQGPALQTGLAGDAFDDDSVEFRIAEIEKSILSLEKGINKAPSPVKAPSPTELLGTAVVRMPAPGMGICGEVSRVVAGPEAPSFHSWLHVAFPTSPVRRTCATACHKAFFLADVPAKHTSVASTKLVFSGPKTIYQQVLQPSRHTIAPWAATEVVPNVIGSLAGPSPLTLEASGKVFVKPLASAPGAALVQQQLEHTSIITLQAAEKKITVEEVQSPPRATHSAKNILEDISNMFDDLADQLDAMLD", "length": 1536, "header": "tr|A0A8V1AEU9-1|A0A8V1AEU9_CHICK Isoform 1 of Caskin-2 OS=Gallus gallus OX=9031 GN=CASKIN2 PE=1 SV=1 CANONICAL=A0A8V1AEU9-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AEU9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEU9/entry#A0A8V1AEU9-1", "sequence": { "sequence": "MGREQDLIQAVKNGDIPGVQKLVAKIKASKSKLLGSAKRLNVNYQDADGFSALHHAALGGSLDLISLLLEAQATVDIKDSNGMRPLHYAAWQGRVEPVRVLLRAAASVNMASLDGQIPLHLSAQYGHYEVSEMLLQHQSNPCLINKAKKTPLDLACEFGRLKVAQLLLNSHLCVALLEGQSKDVTDPNYTTPLHLAAKNGHKEIIRQLLKAGIEINKQTKTGTALHEAALYGKTEVVRLLLEGGVDVNIRNTYNQTALDIVNQFTTSHASKDIKQLLREASGILKVRALKDFWNLHDPTALNVRAGDIITVLEQHPDGRWKGHIHDIQKGTDRVGYFPPSIAEVISKRIGMILPRMAPTHQHQGTPGALMALPDCSPPRLQHLPDECPQQAAPGIPPSYGHLTLTWTAPGPDSSAGDRNSVGSEGSIGSIRSAGSGQSTEGTNGQNTNIVIENTRPLPSTGDDLQQHLLGSEPLNEQINSTTGPPGYQTPSSCTPGDKVFSHQFLRPEQLLEGKDAEAIYNWLSEFQLESYTVNFLSAGYDVPTISRMTPEDLTAIGVTKPGHRKKISTEIGQLSIAEWLPNYIPADLMDWLSAIGLPQYHKKLVNNGYDSITIVTDLTWEDLQEIGINKLGHQKKIMLAVKKLRDLRKSLSQAEATLTRHKVPGALHIVTIESLENGECQSPNTPKMTTFQDSELSYELQTAMSNSCHETLSIKNSQGMSQSQESIGVRSRGSGHSQDNVLSWHLSSPSQESLGSGESSSSSSGQSCMPPHSKESLASLPRQPSPEPYGKLTSPEGLNSFTNGSGGSPLKERNLPEGTDQYAQLTAQKGAGPVGTLMVTPSTPPQTPSMATAPYVFMYPHVSLKSPRAPSSQGAEQPKTLAHSYPSFSSGQKNSLQTSAPKAFSYLHSQCSPAELLEAATAPNAWQTGEQHKGGESSKNKKRSHSLNRYALSDGEHEEEEGMPTSTLGSYATLTRRPGRSQMPRACLQTEAKVTRSQSFAIRAKRKGPPPPPPKRLSSVSSTLTTEVDSEQLPDPERQSSVPQDAADMGASPGDSGCSRTVRSLVATLEETPGLNPPKPLLAPKPLHVAQDSLSKAAVDDRSHNSCDPSSTALSDSGQDPFDSSKPRRRTLSEPSTPMTEAVQGRQEDACSDTEEEAKPEVSSSSQNSSSECIPFAEEGNLTIKQRPKPAGHPKADAAVQDTEPSSQPAESTCSDGKELAVSAVTRELPMLEFNLTESDTVKRRPRFKEREPLQAVLKAFSMAGQAEVGASSAPQYAQAQAVSILGPTTQGPALQTGLAGDAFDDDSVEFRIAEIEKSILSLEKGINKAPSPVKAPSPTELLGTAVVRMPAPGMGICGEVSRVVAGPEAPSFHSWLHVAFPTSPVRRTCATACHKAFFLADVPAKHTSVASTKLVFSGPKTIYQQVLQPSRHTIAPWAATEVVPNVIGSLAGPSPLTLEASGKVFVKPLASAPGAALVQQQLEHTSIITLQAAEKKITVEEVQSPPRATHSAKNILEDISNMFDDLADQLDAMLD", "length": 1536, "header": "tr|A0A8V1AEU9-1|A0A8V1AEU9_CHICK Isoform 1 of Caskin-2 OS=Gallus gallus OX=9031 GN=CASKIN2 PE=1 SV=1 CANONICAL=A0A8V1AEU9-1" }, "locus": { "chromosome": "18", "start_pos": 11496435, "end_pos": 11470882, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071868.1", "url": "https://www.ensembl.org/id/ENSGALT00010071868.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044558.1", "url": "https://www.ensembl.org/id/ENSGALP00010044558.1" } ] } }, { "isoform_ac": "A0A8V1APW4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEU9/entry#A0A8V1APW4-1", "sequence": { "sequence": 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"length": 1467, "header": "tr|A0A8V1APW4-1|A0A8V1AEU9_CHICK Computationally mapped isoform of Caskin-2 OS=Gallus gallus OX=9031 GN=CASKIN2 PE=1 SV=1 CANONICAL=A0A8V1AEU9-1" }, "locus": { "chromosome": "18", "start_pos": 11480856, "end_pos": 11470882, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071864.1", "url": "https://www.ensembl.org/id/ENSGALT00010071864.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044554.1", "url": "https://www.ensembl.org/id/ENSGALP00010044554.1" } ] } }, { "isoform_ac": "A0A8V1APW6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEU9/entry#A0A8V1APW6-1", "sequence": { "sequence": "MGREQDLIQAVKNGDIPGVQKLVAKIKASKSKLLGSAKRLNVNYQDADGFSALHHAALGGSLDLISLLLEAQATVDIKDSNGMRPLHYAAWQGRVEPVRVLLRAAASVNMASLDGQIPLHLSAQYGHYEVSEMLLQHQSNPCLINKAKKTPLDLACEFGRLKVAQLLLNSHLCVALLEGQSKDVTDPNYTTPLHLAAKNGHKEIIRQLLKAGIEINKQTKTGTALHEAALYGKTEVVRLLLEGGVDVNIRNTYNQTALDIVNQFTTSHASKDIKQLLREASGILKVRALKDFWNLHDPTALNVRAGDIITVLEQHPDGRWKGHIHDIQKGTDRVGYFPPSIAEVISKRIAGDRNSVGSEGSIGSIRSAGSGQSTEGTNGQNTNIVIENTRPLPSTGDDLQQHLLGSEPLNEQINSTTGPPGYQTPSSCTPGDKVFSHQFLRPEQLLEGKDAEAIYNWLSEFQLESYTVNFLSAGYDVPTISRMTPEDLTAIGVTKPGHRKKISTEIGQLSIAEWLPNYIPADLMDWLSAIGLPQYHKKLVNNGYDSITIVTDLTWEDLQEIGINKLGHQKKIMLAVKKLRDLRKSLSQAEATLTRHKVPGALHIVTIESLENGECQSPNTPKMTTFQDSELSYELQTAMSNSCHETLSIKNSQGMSQSQESIGVRSRGSGHSQDNVLSWHLSSPSQESLGSGESSSSSSGQSCMPPHSKESLASLPRQPSPEPYGKLTSPEGLNSFTNGSGGSPLKERNLPEGTDQYAQLTAQKGAGPVGTLMVTPSTPPQTPSMATAPYVFMYPHVSLKSPRAPSSQGAEQPKTLAHSYPSFSSGQKNSLQTSAPKAFSYLHSQCSPAELLEAATAPNAWQTGEQHKGGESSKNKKRSHSLNRYALSDGEHEEEEGMPTSTLGSYATLTRRPGRSQMPRACLQTEAKVTRSQSFAIRAKRKGPPPPPPKRLSSVSSTLTTEVDSEQLPDPERQSSVPQDAADMGASPGDSGCSRTVRSLVATLEETPGLNPPKPLLAPKPLHVAQDSLSKAAVDDRSHNSCDPSSTALSDSGQDPFDSSKPRRRTLSEPSTPMTEAVQGRQEDACSDTEEEAKPEVSSSSQNSSSECIPFAEEGNLTIKQRPKPAGHPKADAAVQDTEPSSQPAESTCSDGKELAVSAVTRELPMLEFNLTESDTVKRRPRFKEREPLQAVLKAFSMAGQAEVGASSAPQYAQAQAVSILGPTTQGPALQTGLAGDAFDDDSVEFRIAEIEKSILSLEKGINKAPSPVKAPSPTELLGTAVVRMPAPGMGICGEVSRVVAGPEAPSFHSWLHVAFPTSPVRRTCATACHKAFFLADVPAKHTSVASTKLVFSGPKTIYQQVLQPSRHTIAPWAATEVVPNVIGSLAGPSPLTLEASGKVFVKPLASAPGAALVQQQLEHTSIITLQAAEKKITVEEVQSPPRATHSAKNILEDISNMFDDLADQLDAMLD", "length": 1471, "header": "tr|A0A8V1APW6-1|A0A8V1AEU9_CHICK Computationally mapped isoform of Caskin-2 OS=Gallus gallus OX=9031 GN=CASKIN2 PE=1 SV=1 CANONICAL=A0A8V1AEU9-1" }, "locus": { "chromosome": "18", "start_pos": 11496435, "end_pos": 11470882, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071869.1", "url": "https://www.ensembl.org/id/ENSGALT00010071869.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044559.1", "url": "https://www.ensembl.org/id/ENSGALP00010044559.1" } ] } }, { "isoform_ac": "E1C2D3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEU9/entry#E1C2D3-1", "sequence": { "sequence": "MGREQDLIQAVKNGDIPGVQKLVAKIKASKSKLLGSAKRLNVNYQDADGFSALHHAALGGSLDLISLLLEAQATVDIKDSNGMRPLHYAAWQGRVEPVRVLLRAAASVNMASLDGQIPLHLSAQYGHYEVSEMLLQHQSNPCLINKAKKTPLDLACEFGRLKVAQLLLNSHLCVALLEGQSKDVTDPNYTTPLHLAAKNGHKEIIRQLLKAGIEINKQTKTGTALHEAALYGKTEVVRLLLEGGVDVNIRNTYNQTALDIVNQFTTSHASKDIKQLLREASGILKVRALKDFWNLHDPTALNVRAGDIITVLEQHPDGRWKGHIHDIQKGTDRVGYFPPSIAEVISKRIGMILPRMAPTHQHQGTPGALMALPDCSPPRLQHLPDECPQQAAPGIPPSYGHLTLTWTAPGPDSSAGDRNSVGSEGSIGSIRSAGSGQSTEGTNGQNTNIVIENTRPLPSTGDDLQQHLLGSEPLNEQINSTTGPPGYQTPSSCTPGDKVFSHQFLRPEQLLEGKDAEAIYNWLSEFQLESYTVNFLSAGYDVPTISRMTPEDLTAIGVTKPGHRKKISTEIGQLSIAEWLPNYIPADLMDWLSAIGLPQYHKKLVNNGYDSITIVTDLTWEDLQEIGINKLGHQKKIMLAVKKLRDLRKSLSQAEATLTRHKVPGALHIVTIESLENGECQSPNTPKMTTFQDSELSYELQTAMSNSCHETLSIKNSQGMSQSQESIGVRSRGSGHSQDNVLSWHLSSPSQESLGSGESSSSSSGQSCMPPHSKESLASLPRQPSPEPYGKLTSPEGLNSFTNGSGGSPLKERNLPEGTDQYAQLTAQKGAGPVGTLMVTPSTPPQTPSMATAPYVFMYPHVSLKSPRAPSSQGAEQPKTLAHSYPSFSSGQKNSLQTSAPKAFSYLHSQCSPAELLEAATAPNAWQTGEQHKGGESSKNKKRSHSLNRYALSDGEHEEEEGMPTSTLGSYATLTRRPGRSQMPRACLQTEAKVTRSQSFAIRAKRKGPPPPPPKRLSSVSSTLTTEVDSEQLPDPERQSSVPQDAADMGASPGDSGCSRTVRSLVATLEETPGLNPPKPLLAPKPLHVAQDSLSKAAVDDRSHNSCDPSSTALSDSGQDPFDSSKPRRRTLSEPSTPMTEAVQGRQEDACSDTEEEAKPEVSSSSQNSSSECIPFAEEGNLTIKQRPKPAGHPKADAAVQDTEPSSQPAESTCSDGKELAVSAVTRELPMLEFNLTESDTVKRRPRFKEREPLQAVLKAFSMAGQAEVGASSAPQYAQAQAVSILGPTTQGPALQTGLAGDAFDDDSVEFRIAEIEKSILSLEKGINKAPSPVKAPSPTELLGTAVVRMPAPDVPAKHTSVASTKLVFSGPKTIYQQVLQPSRHTIAPWAATEVVPNVIGSLAGPSPLTLEASGKVFVKPLASAPGAALVQQQLEHTSIITLQAAEKKITVEEVQSPPRATHSAKNILEDISNMFDDLADQLDAMLD", "length": 1488, "header": "tr|E1C2D3-1|A0A8V1AEU9_CHICK Computationally mapped isoform of Caskin-2 OS=Gallus gallus OX=9031 GN=CASKIN2 PE=1 SV=2 CANONICAL=A0A8V1AEU9-1" }, "locus": { "chromosome": "18", "start_pos": 11496435, "end_pos": 11470882, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071866.1", "url": "https://www.ensembl.org/id/ENSGALT00010071866.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044556.1", "url": "https://www.ensembl.org/id/ENSGALP00010044556.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 494, "start_aa": "Thr", "end_pos": 494, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr494", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:422125", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422125", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEU9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEU9" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEU9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEU9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEU9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEU9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1168, "end_pos": 1170, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1181, "end_pos": 1183, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1235, "end_pos": 1237, "annotation": "n_glycosylation_sequon" }, { "start_pos": 188, "end_pos": 190, "annotation": "n_glycosylation_sequon" }, { "start_pos": 254, "end_pos": 256, "annotation": "n_glycosylation_sequon" }, { "start_pos": 479, "end_pos": 481, "annotation": "n_glycosylation_sequon" }, { "start_pos": 803, "end_pos": 805, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AEU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEU9" }, { "id": "PS50105", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50105" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SAM", "eco_id": "ECO_0000259", "start_pos": 514, "end_pos": 577, "start_aa": "Lys", "end_aa": "Ala", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1AEU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEU9" }, { "id": "PS50002", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50002" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SH3", "eco_id": "ECO_0000259", "start_pos": 281, "end_pos": 347, "start_aa": "Ser", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { 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"url": "https://www.ebi.ac.uk/interpro/entry/IPR036938", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039667", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039667", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A9V1", "url": "https://www.orthodb.org/?gene=A0A8V1A9V1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AF46", "url": "https://www.orthodb.org/?gene=A0A8V1AF46", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AF52", "url": "https://www.orthodb.org/?gene=A0A8V1AF52", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AHE2", "url": "https://www.orthodb.org/?gene=A0A8V1AHE2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ALE6", "url": "https://www.orthodb.org/?gene=A0A8V1ALE6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": 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"Protein" ] }, { "id": "A0A8V1AF46-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF46-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AF52", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF52", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AF52-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF52-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHE2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHE2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHE2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHE2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALE6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALE6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALE6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALE6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLSGSHGPVKVRYGPLVSWHWLTLSGMITVGCQKVLSRLPRVGFGCLGVRRLAEMCPVNLCAQTPVESFGFTFGVFLLPCTEQTLTILFLLLFPEAHSTVTTKYGMPSSHSQFMWFFSVYSFLFLYLRMHQTNNARFLDLLWRHVLSICLVTVALLVSYSRVYLLYHTWSQVLYGGVAGSVMAIAWFAFTQEILTPLFPRIAAWPISEFFLIRDTSLIPNILWFEYTVTRAEARNRQRKLGTKLQ", "length": 245, "header": "tr|A0A8V1AF52-1|A0A8V1AF52_CHICK Isoform 1 of Dolichyldiphosphatase OS=Gallus gallus OX=9031 GN=DOLPP1 PE=1 SV=1 CANONICAL=A0A8V1AF52-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A9V1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF52/entry#A0A8V1A9V1-1", "sequence": { "sequence": "MVATDSSNLSSLKTSSTELLLSQLSSAASDFSGQLLAYLSLGPIFIIVGFVTLIIFKRELHTISFLGGLAFNEGVNWLIKNVIREPRPCEEAHSTVTTKYGMPSSHSQFMWFFSVYSFLFLYLRMHQTNNARFLDLLWRHVLSICLVTVALLVSYSRVYLLYHTWSQVLYGGVAGSVMAIAWFAFTQEILTPLFPRIAAWPISEFFLIRDTSLIPNILWFEYTVTRAEARNRQRKLGTKLQ", "length": 241, "header": "tr|A0A8V1A9V1-1|A0A8V1AF52_CHICK Computationally mapped isoform of Dolichyldiphosphatase OS=Gallus gallus OX=9031 GN=DOLPP1 PE=1 SV=1 CANONICAL=A0A8V1AF52-1" }, "locus": { "chromosome": "17", "start_pos": 6091421, "end_pos": 6081041, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069307.1", "url": "https://www.ensembl.org/id/ENSGALT00010069307.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042742.1", "url": "https://www.ensembl.org/id/ENSGALP00010042742.1" } ] } }, { "isoform_ac": "A0A8V1AF46-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF52/entry#A0A8V1AF46-1", "sequence": { "sequence": "MVIVVSWLAVISAGGCQAPLIPAFEPACDFSGQLLAYLSLGPIFIIVGFVTLIIFKRELHTISFLGGLAFNEGVNWLIKNVIREPRPCEEAHSTVTTKYGMPSSHSQFMWFFSVYSFLFLYLRMHQTNNARFLDLLWRHVLSICLVTVALLVSYSRVYLLYHTWSQVLYGGVAGSVMAIAWFAFTQEILTPLFPRIAAWPISEFFLIRDTSLIPNILWFEYTVTRAEARNRQRKLGTKLQ", "length": 240, "header": "tr|A0A8V1AF46-1|A0A8V1AF52_CHICK Computationally mapped isoform of Dolichyldiphosphatase OS=Gallus gallus OX=9031 GN=DOLPP1 PE=1 SV=1 CANONICAL=A0A8V1AF52-1" }, "locus": { "chromosome": "17", "start_pos": 6091421, "end_pos": 6085116, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069301.1", "url": "https://www.ensembl.org/id/ENSGALT00010069301.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042739.1", "url": "https://www.ensembl.org/id/ENSGALP00010042739.1" } ] } }, { "isoform_ac": "A0A8V1AF52-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF52/entry#A0A8V1AF52-1", "sequence": { "sequence": "MLSGSHGPVKVRYGPLVSWHWLTLSGMITVGCQKVLSRLPRVGFGCLGVRRLAEMCPVNLCAQTPVESFGFTFGVFLLPCTEQTLTILFLLLFPEAHSTVTTKYGMPSSHSQFMWFFSVYSFLFLYLRMHQTNNARFLDLLWRHVLSICLVTVALLVSYSRVYLLYHTWSQVLYGGVAGSVMAIAWFAFTQEILTPLFPRIAAWPISEFFLIRDTSLIPNILWFEYTVTRAEARNRQRKLGTKLQ", "length": 245, "header": "tr|A0A8V1AF52-1|A0A8V1AF52_CHICK Isoform 1 of Dolichyldiphosphatase OS=Gallus gallus OX=9031 GN=DOLPP1 PE=1 SV=1 CANONICAL=A0A8V1AF52-1" }, "locus": { "chromosome": "17", "start_pos": 6091421, "end_pos": 6087252, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069310.1", "url": "https://www.ensembl.org/id/ENSGALT00010069310.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042744.1", "url": "https://www.ensembl.org/id/ENSGALP00010042744.1" } ] } }, { "isoform_ac": "A0A8V1AHE2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF52/entry#A0A8V1AHE2-1", "sequence": { "sequence": "MWGGKDAASFAAACAYAGLKWLWAHTHGHCCDFSGQLLAYLSLGPIFIIVGFVTLIIFKRELHTISFLGGLAFNEGVNWLIKNVIREPRPCEEAHSTVTTKYGMPSSHSQFMWFFSVYSFLFLYLRMHQTNNARFLDLLWRHVLSICLVTVALLVSYSRVYLLYHTWSQVLYGGVAGSVMAIAWFAFTQEILTPLFPRIAAWPISEFFLIRDTSLIPNILWFEYTVTRAEARNRQRKLGTKLQ", "length": 243, "header": "tr|A0A8V1AHE2-1|A0A8V1AF52_CHICK Computationally mapped isoform of Dolichyldiphosphatase OS=Gallus gallus OX=9031 GN=DOLPP1 PE=1 SV=1 CANONICAL=A0A8V1AF52-1" }, "locus": { "chromosome": "17", "start_pos": 6091421, "end_pos": 6085037, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069305.1", "url": "https://www.ensembl.org/id/ENSGALT00010069305.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042741.1", "url": "https://www.ensembl.org/id/ENSGALP00010042741.1" } ] } }, { "isoform_ac": "A0A8V1ALE6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF52/entry#A0A8V1ALE6-1", "sequence": { "sequence": "MVAVGDFSGQLLAYLSLGPIFIIVGFVTLIIFKRELHTISFLGGLAFNEGVNWLIKNVIREPRPCEEAHSTVTTKYGMPSSHSQFMWFFSVYSFLFLYLRMHQTNNARFLDLLWRHVLSICLVTVALLVSYSRVYLLYHTWSQVLYGGVAGSVMAIAWFAFTQEILTPLFPRIAAWPISEFFLIRDTSLIPNILWFEYTVTRAEARNRQRKLGTKLQ", "length": 217, "header": "tr|A0A8V1ALE6-1|A0A8V1AF52_CHICK Computationally mapped isoform of Dolichyldiphosphatase OS=Gallus gallus OX=9031 GN=DOLPP1 PE=1 SV=1 CANONICAL=A0A8V1AF52-1" }, "locus": { "chromosome": "17", "start_pos": 6091421, "end_pos": 6080090, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069308.1", "url": "https://www.ensembl.org/id/ENSGALT00010069308.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042743.1", "url": "https://www.ensembl.org/id/ENSGALP00010042743.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AF52", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF52" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "protein N-linked glycosylation", "id": "GO:0006487", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006487", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AF52", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF52" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "dolichyldiphosphatase activity", "id": "GO:0047874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047874", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AF52", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF52" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "14385", "name": "", "equation": "a di-trans,poly-cis-dolichyl diphosphate + H2O = a di-trans,poly-cis-dolichyl phosphate + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V1AF52-1" ], "evidence": [ { "id": "14385", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/14385" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A8V1AF52", "gene_name": "DOLPP1", "activity": [ { "ec_number": "3.6.1.43", "activity": "a di-trans,poly-cis-dolichyl diphosphate + H2O = a di-trans,poly-cis-dolichyl phosphate + phosphate + H(+).", "evidence": [ { "id": "A0A8V1AF52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF52" } ] }, { "ec_number": "3.6.1.43", "activity": "", "evidence": [ { "id": "A0A8V1AF52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF52" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AF52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF52" }, { "id": "SM00014", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00014" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Phosphatidic acid phosphatase type 2/haloperoxidase", "eco_id": "ECO_0000259", "start_pos": 66, "end_pos": 187, "start_aa": "Val", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.6.1.43", "ec_name": "a di-trans,poly-cis-dolichyl diphosphate + H2O = a di-trans,poly-cis-dolichyl phosphate + phosphate + H(+).", "evidence": [ { "id": "3.6.1.43", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.43" }, { "id": "3.6.1.43", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.6.1.43" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AF47-1", "uniprot_ac": "A0A8V1AF47", "uniprot_id": "A0A8V1AF47_CHICK", "mass": { "chemical_mass": 48325.0, "monoisotopic_mass": 48325.0 }, "refseq": {}, "gene_names": [ { "name": "CD244", "type": "recommended", "evidence": [ { "id": "A0A8V1AF47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF47" } ] } ], "protein_names": [ { "name": "CD244 molecule", "type": 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"https://www.ncbi.nlm.nih.gov/gene/425935", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015631", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015631", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024303", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024303", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A4V6", "url": "https://www.orthodb.org/?gene=A0A8V1A4V6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A9R8", "url": "https://www.orthodb.org/?gene=A0A8V1A9R8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ACI1", "url": "https://www.orthodb.org/?gene=A0A8V1ACI1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AF47", "url": "https://www.orthodb.org/?gene=A0A8V1AF47", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AF51", "url": "https://www.orthodb.org/?gene=A0A8V1AF51", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AH52", "url": "https://www.orthodb.org/?gene=A0A8V1AH52", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AH57", "url": "https://www.orthodb.org/?gene=A0A8V1AH57", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12080", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12080", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12080:SF56", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12080:SF56", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF11465", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11465", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-202733", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-202733", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1A4V6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A4V6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A9R8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9R8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A9R8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9R8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ACI1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACI1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ACI1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACI1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AF47", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF47", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AF47-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF47-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AF51", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF51", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AF51-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF51-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AH52", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH52", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AH52-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH52-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AH57", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH57", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AH57-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH57-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLHGQLQYVARVHGVDRHPALQELGARGDPSLLHLHQGVVPRGDESAAQWGAAQGSPSQTVPLHGDTALTLCPPPGTGECRNRTVLTGSDLHLLLEEPLPPDWSAVQWKVTLEAQARQRILTVRKDKIYHTNSSLSQRATFHWEPLSLQIRAVTQADSGIYNAEIEESTGSVWTKCFHVSVWEPVGSPRLETLVLQEEQGRCHLQLSCTVPGATAVSYSWSRDSDPLGNQSVLLVSEYVQPVLYVCNVSNPASWSTASIDMATACTQKGLFGAVPWWAVTVLLVLAVCIAGSITFWCWRRRGKDYPAASTIVAPSEHTDPPLTVYEEVGRVRTGQEPNRNSEAHAVGNTIYAMVHPKEQKPKSPQNPESCTIYSTVQHRMKPPPLSPDPRSALQSPSFRRKKLDPVLVSTAYMEVTAPLRRGYTPSQRSSPSPMDHHNS", "length": 439, "header": "tr|A0A8V1AF47-1|A0A8V1AF47_CHICK Isoform 1 of CD244 molecule OS=Gallus gallus OX=9031 GN=CD244 PE=4 SV=1 CANONICAL=A0A8V1AF47-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A4V6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF47/entry#A0A8V1A4V6-1", "sequence": { "sequence": "MQQHGGALHALEMLLCLVLGAADSGQGTGECRNRTVLTGSDLHLLLEEPLPPDWSAVQWKVTLEAQARQRILTIRAVTQADSGIYNAEIEESTGSVWTKCFHVSVWEPVGSPRLETLVLQEEQGRCHLQLSCTVPGATAVSYSWSRDSDPLGNQSVLLVSEYVQPVLYVCNVSNPASWSTASIDMATACTQKGLFGAVPWWAVTVLLVLAVCIAGSITFWCWRRRGKDYPAEHTDPPLTVYEEVGRVRTGQEPNRNSEAHAVGNTIYAMVHPKEQKPKSPQNPESCTIYSTVQHRMKPPPLSPDPRSALQSPSFRRKKLDPVLVSTAYMEVTAPLRRGYTPSQRSSPSPMDHHNS", "length": 355, "header": "tr|A0A8V1A4V6-1|A0A8V1AF47_CHICK Computationally mapped isoform of CD244 molecule OS=Gallus gallus OX=9031 GN=CD244 PE=4 SV=1 CANONICAL=A0A8V1AF47-1" }, "locus": { "chromosome": "25", "start_pos": 1193233, "end_pos": 1189655, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066935.1", "url": "https://www.ensembl.org/id/ENSGALT00010066935.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040944.1", "url": "https://www.ensembl.org/id/ENSGALP00010040944.1" } ] } }, { "isoform_ac": "A0A8V1A9R8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF47/entry#A0A8V1A9R8-1", "sequence": { "sequence": "HGVDRHPALQELGARGDPSLLHLHQGVVPRGDESAAQWGTGECRNRTVLTGSDLHLLLEEPLPPDWSAVQWKVTLEAQARQRILTVRKDKIYHTNSSLSQRATFHWEPLSLQIRAVTQADSGIYNAEIEESTGSVWTKCFHVSVWEPVGSPRLETLVLQEEQGRCHLQLSCTVPGATAVSYSWSRDSDPLGNQSVLLVSEYVQPVLYVCNVSNPASWSTASIDMATACTQKGLFGAVPWWAVTVLLVLAVCIAGSITFWCWRRRGKDYPAEHTDPPLTVYEEVGRVRTGQEPNRNSEAHAVGNTIYAMVHPKEQKPKSPQNPESCTIYSTVQHRMKSPSFRRKKLDPVLVSTAYMEVTGTGQRADEPCTSPLQVPCFLVTEFG", "length": 383, "header": "tr|A0A8V1A9R8-1|A0A8V1AF47_CHICK Computationally mapped isoform of CD244 molecule OS=Gallus gallus OX=9031 GN=CD244 PE=4 SV=1 CANONICAL=A0A8V1AF47-1" }, "locus": { "chromosome": "25", "start_pos": 1193045, "end_pos": 1190676, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066929.1", "url": "https://www.ensembl.org/id/ENSGALT00010066929.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040941.1", "url": "https://www.ensembl.org/id/ENSGALP00010040941.1" } ] } }, { "isoform_ac": "A0A8V1ACI1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF47/entry#A0A8V1ACI1-1", "sequence": { "sequence": "MQQHGGALHALEMLLCLVLGAADSGQGTGECRNRTVLTGSDLHLLLEEPLPPDWSAVQWKVTLEAQARQRILTVRKDKIYHTNSSLSQRATFHWEPLSLQIRAVTQADSGIYNAEIEESTGSVWTKCFHVSVWEPVGSPRLETLVLQEEQGRCHLQLSCTVPGATAVSYSWSRDSDPLGNQSVLLVSEYVQPVLYVCNVSNPASWSTASIDMATACTQKGLFGAVPWWAVTVLLVLAVCIAGSITFWCWRRRGKDYPAEHTDPPLTVYEEVGRVRTGQEPNRNSEAHAVGNTIYAMVHPKEQKPKSPQNPESCTIYSTVQHRMKVTAPLRRGYTPSQRSSPSPMDHHNS", "length": 349, "header": "tr|A0A8V1ACI1-1|A0A8V1AF47_CHICK Computationally mapped isoform of CD244 molecule OS=Gallus gallus OX=9031 GN=CD244 PE=4 SV=1 CANONICAL=A0A8V1AF47-1" }, "locus": { "chromosome": "25", "start_pos": 1193233, "end_pos": 1189655, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066932.1", "url": "https://www.ensembl.org/id/ENSGALT00010066932.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040943.1", "url": "https://www.ensembl.org/id/ENSGALP00010040943.1" } ] } }, { "isoform_ac": "A0A8V1AF47-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF47/entry#A0A8V1AF47-1", "sequence": { "sequence": "MLHGQLQYVARVHGVDRHPALQELGARGDPSLLHLHQGVVPRGDESAAQWGAAQGSPSQTVPLHGDTALTLCPPPGTGECRNRTVLTGSDLHLLLEEPLPPDWSAVQWKVTLEAQARQRILTVRKDKIYHTNSSLSQRATFHWEPLSLQIRAVTQADSGIYNAEIEESTGSVWTKCFHVSVWEPVGSPRLETLVLQEEQGRCHLQLSCTVPGATAVSYSWSRDSDPLGNQSVLLVSEYVQPVLYVCNVSNPASWSTASIDMATACTQKGLFGAVPWWAVTVLLVLAVCIAGSITFWCWRRRGKDYPAASTIVAPSEHTDPPLTVYEEVGRVRTGQEPNRNSEAHAVGNTIYAMVHPKEQKPKSPQNPESCTIYSTVQHRMKPPPLSPDPRSALQSPSFRRKKLDPVLVSTAYMEVTAPLRRGYTPSQRSSPSPMDHHNS", "length": 439, "header": "tr|A0A8V1AF47-1|A0A8V1AF47_CHICK Isoform 1 of CD244 molecule OS=Gallus gallus OX=9031 GN=CD244 PE=4 SV=1 CANONICAL=A0A8V1AF47-1" }, "locus": { "chromosome": "25", "start_pos": 1193233, "end_pos": 1190640, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066930.1", "url": "https://www.ensembl.org/id/ENSGALT00010066930.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040942.1", "url": "https://www.ensembl.org/id/ENSGALP00010040942.1" } ] } }, { "isoform_ac": "A0A8V1AF51-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF47/entry#A0A8V1AF51-1", "sequence": { "sequence": "TGSDLHLLLEEALPPYWAAVSWKVTLEAQARQRILTVRKDRVDPANSTLISQRATFHWEPLSLQIRAVTQADSGIYYAEIVKSTGSVLNKCFHVSVWEPVGSPRLETLVLQEEQGRCHLQLSCTVPGATAVSYSWSRDSDPLGNQSVLLVSEYVQPVLYVCNVSNPASWSTASIDMATACTQKGLFGAVPWWAVTVLLVLAVCIAGSITFWCWRRRGKDYPAEHTDPPLTVYEEVGRVRTGQEPNRNSEAHAVGNTIYAMVHPKEQKPKSPQNPESCTIYSTVQHRMKPPPLSPDPRSALQSPSFRRKKLDPVLVSTAYMEVTAPLRRGYTPSQRSSPSPMDHHNS", "length": 346, "header": "tr|A0A8V1AF51-1|A0A8V1AF51_CHICK Computationally mapped isoform of CD244 molecule OS=Gallus gallus OX=9031 GN=CD244 PE=4 SV=1 CANONICAL=A0A8V1AF47-1" }, "locus": { "chromosome": "25", "start_pos": 1193233, "end_pos": 1187346, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066940.1", "url": "https://www.ensembl.org/id/ENSGALT00010066940.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040947.1", "url": "https://www.ensembl.org/id/ENSGALP00010040947.1" } ] } }, { "isoform_ac": "A0A8V1AH52-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF47/entry#A0A8V1AH52-1", "sequence": { "sequence": "MQQHGGALHALEMLLCLVLGAADSGQGTGECRNRTVLTGSDLHLLLEEPLPPDWSAVQWKVTLEAQARQRILTVRKDKIYHTNSSLSQRATFHWEPLSLQIRAVTQADSGIYNAEIEESTGSVWTKCFHVSVWEPVGSPRLETLVLQEEQGRCHLQLSCTVPGATAVSYSWSRDSDPLGNQSVLLVSEYVQPVLYVCNVSNPASWSTASIDMATACTQKGLFGAVPWWAVTVLLVLAVCIAGSITFWCWRRRGKDYPAEHTDPPLTVYEEVGRVRTGQEPNRNSEAHAVGNTIYAMVHPKEQKPKSPQNPESCTIYSTVQHRMKQPPPLSPDPRSALQSPSFRRKKLDPVLVSTAYMEVTGTGQRADEPCTSPLQVPCFLVTEFG", "length": 385, "header": "tr|A0A8V1AH52-1|A0A8V1AF47_CHICK Computationally mapped isoform of CD244 molecule OS=Gallus gallus OX=9031 GN=CD244 PE=4 SV=1 CANONICAL=A0A8V1AF47-1" }, "locus": { "chromosome": "25", "start_pos": 1193045, "end_pos": 1189655, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066937.1", "url": "https://www.ensembl.org/id/ENSGALT00010066937.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040945.1", "url": "https://www.ensembl.org/id/ENSGALP00010040945.1" } ] } }, { "isoform_ac": "A0A8V1AH57-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF47/entry#A0A8V1AH57-1", "sequence": { "sequence": "MQQHGGALHALEMLLCLVLGAAGSGQGTGECRNRTVLTGSDLHLLLEEPLPPDWSAVQWKVTLEAQARQRILTVRKDKIYHTNSSLSQRATFHWEPLSLQIRAVTQADSGIYNAEIEESTGSVWTKCFHVSVWEPVGSPRLETLVLQEEQGRCHLQLSCTVPGATAVSYSWSRDSDPLGNQSVLLVSEYVQPVLYVCNVSNPASWSTASIDMATACTQKGLFGAVPWWAVTVLLVLAVCIAGSITFWCWRRRGKDYPAEHTDPPLTVYEEVGRVRTGQEPNRNSEAHAVGNTIYAMVHPKEQKPKSPQNPESCTIYSTVQHRMKPPPLSPDPRSALQSPSFRRKKLDPVLVSTAYMEVTAPLRRGYTPSQRSSPSPMDHHNS", "length": 382, "header": "tr|A0A8V1AH57-1|A0A8V1AF47_CHICK Computationally mapped isoform of CD244 molecule OS=Gallus gallus OX=9031 GN=CD244 PE=4 SV=1 CANONICAL=A0A8V1AF47-1" }, "locus": { "chromosome": "25", "start_pos": 1193233, "end_pos": 1186103, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066943.1", "url": "https://www.ensembl.org/id/ENSGALT00010066943.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040950.1", "url": "https://www.ensembl.org/id/ENSGALP00010040950.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-202733", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-202733", "resource": "Reactome", "description": "Cell surface interactions at the vascular wall" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AF47", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF47" } ], "pmid": "" }, { "name": "external side of plasma membrane", "id": "GO:0009897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009897", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AF47", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF47" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "immune response", "id": "GO:0006955", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006955", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AF47", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF47" } ], "pmid": "" }, { "name": "natural killer cell activation involved in immune response", "id": "GO:0002323", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002323", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AF47", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF47" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "MHC class I protein binding", "id": "GO:0042288", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042288", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AF47", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF47" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 132, "end_pos": 134, "annotation": "n_glycosylation_sequon" }, { "start_pos": 229, "end_pos": 231, "annotation": "n_glycosylation_sequon" }, { "start_pos": 247, "end_pos": 249, "annotation": "n_glycosylation_sequon" }, { "start_pos": 82, "end_pos": 84, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AF47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF47" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 188, "end_pos": 262, "start_aa": "Pro", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 132, "end_pos": 134 }, { "start_pos": 229, "end_pos": 231 }, { "start_pos": 247, "end_pos": 249 }, { "start_pos": 82, "end_pos": 84 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { 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"start_pos": 339, "end_pos": 341 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AEV9-1", "uniprot_ac": "A0A8V1AEV9", "uniprot_id": "A0A8V1AEV9_CHICK", "mass": { "chemical_mass": 63015.0, "monoisotopic_mass": 63015.0 }, "refseq": {}, "gene_names": [ { "name": "PRKAG2", "type": "recommended", "evidence": [ { "id": "A0A8V1AEV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEV9" } ] } ], "protein_names": [ { "name": "Protein kinase AMP-activated non-catalytic subunit gamma 2", "type": "synonym", "evidence": [ { "id": "A0A8V1AEV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEV9/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEV9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEV9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PRKAG2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEV9", "locus": { "chromosome": "2", "start_pos": 6310327, "end_pos": 6492412, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027135", "url": "https://www.ensembl.org/id/ENSGALG00010027135" } ] } } ], "crossref": [ { "id": "A0A8V1AEV9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AEV9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000006219", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000006219", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd04618", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04618", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd04641", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04641", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "420435", "url": "https://www.ncbi.nlm.nih.gov/gene/420435", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000644", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000644", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046342", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046342", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050511", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050511", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "XVQIYEL", "url": "https://omabrowser.org/oma/group/XVQIYEL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PYS9", "url": "https://www.orthodb.org/?gene=A0A1D5PYS9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A1L1RXN3", "url": "https://www.orthodb.org/?gene=A0A1L1RXN3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A2E4", "url": "https://www.orthodb.org/?gene=A0A8V1A2E4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A7E4", "url": "https://www.orthodb.org/?gene=A0A8V1A7E4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A9Z4", "url": "https://www.orthodb.org/?gene=A0A8V1A9Z4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ACU6", "url": "https://www.orthodb.org/?gene=A0A8V1ACU6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AEV9", "url": "https://www.orthodb.org/?gene=A0A8V1AEV9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AEW5", "url": "https://www.orthodb.org/?gene=A0A8V1AEW5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NXI9", "url": "https://www.orthodb.org/?gene=F1NXI9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NXL4", "url": "https://www.orthodb.org/?gene=F1NXL4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13780", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13780", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13780:SF122", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13780:SF122", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00571", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00571", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-1632852", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1632852", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-380972", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-380972", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5628897", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5628897", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9931269", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9931269", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A1D5PYS9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PYS9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PYS9-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PYS9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1L1RXN3", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RXN3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1L1RXN3-1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RXN3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A2E4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2E4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A2E4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2E4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A7E4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A7E4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A9Z4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9Z4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A9Z4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9Z4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ACU6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACU6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ACU6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACU6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AEV9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEV9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AEV9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEV9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AEW5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEW5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AEW5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEW5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NXI9", "url": "https://www.uniprot.org/uniprotkb/F1NXI9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NXI9-1", "url": "https://www.uniprot.org/uniprotkb/F1NXI9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NXL4", "url": "https://www.uniprot.org/uniprotkb/F1NXL4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NXL4-1", "url": "https://www.uniprot.org/uniprotkb/F1NXL4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSQEPHHGKLQAPAGKSLACSSSMDVSSQTAGFFRADLSSFAMPFLDGDVENTDKNASRKVEESYSAGSPSKGIFSKGLQNRPSSPVSAPVRSKHSPGSPKTVFPFPYQESPPRSPRRMSFSGIFRSSSKESSPNSNPSTSPGGIKFFSRSRKTSGLSSSPSTPTQVTKQPTFPLESYKHEPERLETRIHCSSPPDTGQRFSLPPSQSAAKPPIMTPSPCATSKPAAAAAPAPSQLPAASEGMLEKLELEDEALEESESDIYVRFMRSHKCYDIVPTSSKLVVFDTTLQVKKAFFALVANGVRAAPLWESKKQSFVGMLTITDFINILHRYYKSPMVQIYELEEHKIETWRELYLQETFKPLVNISPDASLFDAVYSLIKNKIHRLPVIDPVSGNALYILTHKRILKFLQLFMSEMPKPAFMKKNLDELGIGTYHNIAFIHPDTPIIKALNIFVERRISALPVVDESGKVVDIYSKFDVINLAAEKTYNNLDITVTQALQHRSQYFEGVVKCSMLETLETIVDRIVKAEVHRLVVVNEADSIVGIISLSDILQALVLTPAGAKQKENESE", "length": 570, "header": "tr|A0A8V1AEV9-1|A0A8V1AEV9_CHICK Isoform 1 of Protein kinase AMP-activated non-catalytic subunit gamma 2 OS=Gallus gallus OX=9031 GN=PRKAG2 PE=1 SV=1 CANONICAL=A0A8V1AEV9-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PYS9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEV9/entry#A0A1D5PYS9-1", "sequence": { "sequence": "MKIILQETEIRSDLSSFAMPFLDGDVENTDKNASRKVEESYSAGSPSKGIFSKGLQNRPSSPVSAPVRSKHSPGSPKTVFPFPYQESPPRSPRRMSFSGIFRSSSKESSPNSNPSTSPGGIKFFSRSRKTSGLSSSPSTPTQVTKQPTFPLESYKHEPERLETRIHCSSPPDTGQRFSLPPSQSAAKPPIMTPSPCATSKPAAAAAPAPSQLPAASEGMLEKLELEDEALEESESDIYVRFMRSHKCYDIVPTSSKLVVFDTTLQVKKAFFALVANGVRAAPLWESKKQSFVGMLTITDFINILHRYYKSPMVQIYELEEHKIETWRELYLQETFKPLVNISPDASLFDAVYSLIKNKIHRLPVIDPVSGNALYILTHKRILKFLQLFMSEMPKPAFMKKNLDELGIGTYHNIAFIHPDTPIIKALNIFVERRISALPVVDESGKVVDIYSKFDVINLAAEKTYNNLDITVTQALQHRSQYFEGVVKCSMLETLETIVDRIVKAEVHRLVVVNEADSIVGIISLSDILQALVLTPAGAKQKENESE", "length": 546, "header": "tr|A0A1D5PYS9-1|A0A1D5PYS9_CHICK Computationally mapped isoform of Protein kinase AMP-activated non-catalytic subunit gamma 2 OS=Gallus gallus OX=9031 GN=PRKAG2 PE=1 SV=1 CANONICAL=A0A8V1AEV9-1" }, "locus": { "chromosome": "2", "start_pos": 6469939, "end_pos": 6311256, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065791.1", "url": "https://www.ensembl.org/id/ENSGALT00010065791.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040057.1", "url": "https://www.ensembl.org/id/ENSGALP00010040057.1" } ] } }, { "isoform_ac": "A0A1L1RXN3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEV9/entry#A0A1L1RXN3-1", "sequence": { "sequence": "MPFLDGDVENTDKNASRKVEESYSAGSPSKGIFSKGLQNRPSSPVSAPVRSKHSPGSPKTVFPFPYQESPPRSPRRMSFSGIFRSSSKESSPNSNPSTSPGGIKFFSRSRKTSGLSSSPSTPTQVTKQPTFPLESYKHEPERLETRIHCSSPPDTGQRFSLPPSQSAAKPPIMTPSPCATSKPAAAAAPAPSQLPAASEGMLEKLELEDEALEESESDIYVRFMRSHKCYDIVPTSSKLVVFDTTLQVKKAFFALVANGVRAAPLWESKKQSFVGMLTITDFINILHRYYKSPMVQIYELEEHKIETWRELYLQETFKPLVNISPDASLFDAVYSLIKNKIHRLPVIDPVSGNALYILTHKRILKFLQLFMSEMPKPAFMKKNLDELGIGTYHNIAFIHPDTPIIKALNIFVERRISALPVVDESGKVVDIYSKFDVINLAAEKTYNNLDITVTQALQHRSQYFEGVVKCSMLETLETIVDRIVKAEVHRLVVVNEADSIVGIISLSDILQALVLTPAGAKQKENESE", "length": 528, "header": "tr|A0A1L1RXN3-1|A0A1L1RXN3_CHICK Computationally mapped isoform of Protein kinase AMP-activated non-catalytic subunit gamma 2 OS=Gallus gallus OX=9031 GN=PRKAG2 PE=1 SV=2 CANONICAL=A0A8V1AEV9-1" }, "locus": { "chromosome": "2", "start_pos": 6431154, "end_pos": 6311256, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065790.1", "url": "https://www.ensembl.org/id/ENSGALT00010065790.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040056.1", "url": "https://www.ensembl.org/id/ENSGALP00010040056.1" } ] } }, { "isoform_ac": "A0A8V1A2E4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEV9/entry#A0A8V1A2E4-1", "sequence": { "sequence": "MLVLGITEIEGNVILLEGSGVSKGLLKDLSSFAMPFLDGDVENTDKNASRKVEESYSAGSPSKGIFSKGLQNRPSSPVSAPVRSKHSPGSPKTVFPFPYQESPPRSPRRMSFSGIFRSSSKESSPNSNPSTSPGGIKFFSRSRKTSGLSSSPSTPTQVTKQPTFPLESYKHEPERLETRIHCSSPPDTGQRFSLPPSQSAAKPPIMTPSPCATSKPAAAAAPAPSQLPAASEGMLEKLELEDEALEESESDIYVRFMRSHKCYDIVPTSSKLVVFDTTLQVKKAFFALVANGVRAAPLWESKKQSFVGMLTITDFINILHRYYKSPMVQIYELEEHKIETWRELYLQETFKPLVNISPDASLFDAVYSLIKNKIHRLPVIDPVSGNALYILTHKRILKFLQLFMSEMPKPAFMKKNLDELGIGTYHNIAFIHPDTPIIKALNIFVERRISALPVVDESGKVVDIYSKFDVINLAAEKTYNNLDITVTQALQHRSQYFEGVVKCSMLETLETIVDRIVKAEVHRLVVVNEADSIVGIISLSDILQALVLTPAGAKQKENESE", "length": 561, "header": "tr|A0A8V1A2E4-1|A0A8V1AEV9_CHICK Computationally mapped isoform of Protein kinase AMP-activated non-catalytic subunit gamma 2 OS=Gallus gallus OX=9031 GN=PRKAG2 PE=1 SV=1 CANONICAL=A0A8V1AEV9-1" }, "locus": { "chromosome": "2", "start_pos": 6487913, "end_pos": 6311256, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065793.1", "url": "https://www.ensembl.org/id/ENSGALT00010065793.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040059.1", "url": "https://www.ensembl.org/id/ENSGALP00010040059.1" } ] } }, { "isoform_ac": "A0A8V1A7E4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEV9/entry#A0A8V1A7E4-1", "sequence": { "sequence": "MLQLMKRFGSFRGSKKRKEQYKGVERRWSDPRGLLASGLSSSPSTPTQVTKQPTFPLESYKHEPERLETRIHCSSPPDTGQRFSLPPSQSAAKPPIMTPSPCATSKPAAAAAPAPSQLPAASEGMLEKLELEDEALEESESDIYVRFMRSHKCYDIVPTSSKLVVFDTTLQVKKAFFALVANGVRAAPLWESKKQSFVGMLTITDFINILHRYYKSPMVSMTLKLYLQETFKPLVNISPDASLFDAVYSLIKNKIHRLPVIDPVSGNALYILTHKRILKFLQLFMSEMPKPAFMKKNLDELGIGTYHNIAFIHPDTPIIKALNIFVERRISALPVVDESGKVVDIYSKFDVINLAAEKTYNNLDITVTQALQHRSQYFEGVVKCSMLETLETIVDRIVKAEVHRLVVVNEADSIVGIISLSDILQALVLTPAGMDVAF", "length": 438, "header": "tr|A0A8V1A7E4-1|A0A8V1AEV9_CHICK Computationally mapped isoform of Protein kinase AMP-activated non-catalytic subunit gamma 2 OS=Gallus gallus OX=9031 GN=PRKAG2 PE=1 SV=1 CANONICAL=A0A8V1AEV9-1" }, "locus": { "chromosome": "2", "start_pos": 6397501, "end_pos": 6312917, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065785.1", "url": "https://www.ensembl.org/id/ENSGALT00010065785.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040051.1", "url": "https://www.ensembl.org/id/ENSGALP00010040051.1" } ] } }, { "isoform_ac": "A0A8V1A9Z4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEV9/entry#A0A8V1A9Z4-1", "sequence": { "sequence": "MDLSSFAMPFLDGDVENTDKNASRKVEESYSAGSPSKGIFSKGLQNRPSSPVSAPVRSKHSPGSPKTVFPFPYQESPPRSPRRMSFSGIFRSSSKESSPNSNPSTSPGGIKFFSRSRKTSGLSSSPSTPTQVTKQPTFPLESYKHEPERLETRIHCSSPPDTGQRFSLPPSQSAAKPPIMTPSPCATSKPAAAAAPAPSQLPAASEGMLEKLELEDEALEESESDIYVRFMRSHKCYDIVPTSSKLVVFDTTLQVKKAFFALVANGVRAAPLWESKKQSFVGMLTITDFINILHRYYKSPMVQIYELEEHKIETWRELYLQETFKPLVNISPDASLFDAVYSLIKNKIHRLPVIDPVSGNALYILTHKRILKFLQLFMSEMPKPAFMKKNLDELGIGTYHNIAFIHPDTPIIKALNIFVERRISALPVVDESGKVVDIYSKFDVINLAAEKTYNNLDITVTQALQHRSQYFEGVVKCSMLETLETIVDRIVKAEVHRLVVVNEADSIVGIISLSDILQALVLTPAGAKQKENESE", "length": 535, "header": "tr|A0A8V1A9Z4-1|A0A8V1AEV9_CHICK Computationally mapped isoform of Protein kinase AMP-activated non-catalytic subunit gamma 2 OS=Gallus gallus OX=9031 GN=PRKAG2 PE=1 SV=1 CANONICAL=A0A8V1AEV9-1" }, "locus": { "chromosome": "2", "start_pos": 6449702, "end_pos": 6311256, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065792.1", "url": "https://www.ensembl.org/id/ENSGALT00010065792.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040058.1", "url": "https://www.ensembl.org/id/ENSGALP00010040058.1" } ] } }, { "isoform_ac": "A0A8V1ACU6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEV9/entry#A0A8V1ACU6-1", "sequence": { "sequence": "MASSKHLQDLSSFAMPFLDGDVENTDKNASRKVEESYSAGSPSKGIFSKGLQNRPSSPVSAPVRSKHSPGSPKTVFPFPYQESPPRSPRRMSFSGIFRSSSKESSPNSNPSTSPGGIKFFSRSRKTSGLSSSPSTPTQVTKQPTFPLESYKHEPERLETRIHCSSPPDTGQRFSLPPSQSAAKPPIMTPSPCATSKPAAAAAPAPSQLPAASEGMLEKLELEDEALEESESDIYVRFMRSHKCYDIVPTSSKLVVFDTTLQVKKAFFALVANGVRAAPLWESKKQSFVGMLTITDFINILHRYYKSPMVQIYELEEHKIETWRELYLQETFKPLVNISPDASLFDAVYSLIKNKIHRLPVIDPVSGNALYILTHKRILKFLQLFMSEMPKPAFMKKNLDELGIGTYHNIAFIHPDTPIIKALNIFVERRISALPVVDESGKVVDIYSKFDVINLAAEKTYNNLDITVTQALQHRSQYFEGVVKCSMLETLETIVDRIVKAEVHRLVVVNEADSIVGIISLSDILQALVLTPAGAKQKENESE", "length": 542, "header": "tr|A0A8V1ACU6-1|A0A8V1AEV9_CHICK Computationally mapped isoform of Protein kinase AMP-activated non-catalytic subunit gamma 2 OS=Gallus gallus OX=9031 GN=PRKAG2 PE=1 SV=1 CANONICAL=A0A8V1AEV9-1" }, "locus": { "chromosome": "2", "start_pos": 6489207, "end_pos": 6311256, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065797.1", "url": "https://www.ensembl.org/id/ENSGALT00010065797.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040063.1", "url": "https://www.ensembl.org/id/ENSGALP00010040063.1" } ] } }, { "isoform_ac": "A0A8V1AEV9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEV9/entry#A0A8V1AEV9-1", "sequence": { "sequence": "MSQEPHHGKLQAPAGKSLACSSSMDVSSQTAGFFRADLSSFAMPFLDGDVENTDKNASRKVEESYSAGSPSKGIFSKGLQNRPSSPVSAPVRSKHSPGSPKTVFPFPYQESPPRSPRRMSFSGIFRSSSKESSPNSNPSTSPGGIKFFSRSRKTSGLSSSPSTPTQVTKQPTFPLESYKHEPERLETRIHCSSPPDTGQRFSLPPSQSAAKPPIMTPSPCATSKPAAAAAPAPSQLPAASEGMLEKLELEDEALEESESDIYVRFMRSHKCYDIVPTSSKLVVFDTTLQVKKAFFALVANGVRAAPLWESKKQSFVGMLTITDFINILHRYYKSPMVQIYELEEHKIETWRELYLQETFKPLVNISPDASLFDAVYSLIKNKIHRLPVIDPVSGNALYILTHKRILKFLQLFMSEMPKPAFMKKNLDELGIGTYHNIAFIHPDTPIIKALNIFVERRISALPVVDESGKVVDIYSKFDVINLAAEKTYNNLDITVTQALQHRSQYFEGVVKCSMLETLETIVDRIVKAEVHRLVVVNEADSIVGIISLSDILQALVLTPAGAKQKENESE", "length": 570, "header": "tr|A0A8V1AEV9-1|A0A8V1AEV9_CHICK Isoform 1 of Protein kinase AMP-activated non-catalytic subunit gamma 2 OS=Gallus gallus OX=9031 GN=PRKAG2 PE=1 SV=1 CANONICAL=A0A8V1AEV9-1" }, "locus": { "chromosome": "2", "start_pos": 6489226, "end_pos": 6311256, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065795.1", "url": "https://www.ensembl.org/id/ENSGALT00010065795.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040061.1", "url": "https://www.ensembl.org/id/ENSGALP00010040061.1" } ] } }, { "isoform_ac": "A0A8V1AEW5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEV9/entry#A0A8V1AEW5-1", "sequence": { "sequence": "MGSTAMDTKKKDSSGSGRRGSSQKKLMLRVHIPVEESYSAGSPSKGIFSKGLQNRPSSPVSAPVRSKHSPGSPKTVFPFPYQESPPRSPRRMSFSGIFRSSSKESSPNSNPSTSPGGIKFFSRSRKTSGLSSSPSTPTQVTKQPTFPLESYKHEPERLETRIHCSSPPDTGQRFSLPPSQSAAKPPIMTPSPCATSKPAAAAAPAPSQLPAASEGMLEKLELEDEALEESESDIYVRFMRSHKCYDIVPTSSKLVVFDTTLQVKKAFFALVANGVRAAPLWESKKQSFVGMLTITDFINILHRYYKSPMVQIYELEEHKIETWRELYLQETFKPLVNISPDASLFDAVYSLIKNKIHRLPVIDPVSGNALYILTHKRILKFLQLFMSEMPKPAFMKKNLDELGIGTYHNIAFIHPDTPIIKALNIFVERRISALPVVDESGKVVDIYSKFDVINLAAEKTYNNLDITVTQALQHRSQYFEGVVKCSMLETLETIVDRIVKAEVHRLVVVNEADSIVGIISLSDILQALVLTPAGAKQKENESE", "length": 543, "header": "tr|A0A8V1AEW5-1|A0A8V1AEW5_CHICK Computationally mapped isoform of Protein kinase AMP-activated non-catalytic subunit gamma 2 OS=Gallus gallus OX=9031 GN=PRKAG2 PE=1 SV=1 CANONICAL=A0A8V1AEV9-1" }, "locus": { "chromosome": "2", "start_pos": 6492213, "end_pos": 6311256, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065800.1", "url": "https://www.ensembl.org/id/ENSGALT00010065800.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040066.1", "url": "https://www.ensembl.org/id/ENSGALP00010040066.1" } ] } }, { "isoform_ac": "F1NXI9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEV9/entry#F1NXI9-1", "sequence": { "sequence": "MLQLMKRFGSFRGSKKRKEQYKGVERRWSDPRGLLASGLSSSPSTPTQVTKQPTFPLESYKHEPERLETRIHCSSPPDTGQRFSLPPSQSAAKPPIMTPSPCATSKPAAAAAPAPSQLPAASEGMLEKLELEDEALEESESDIYVRFMRSHKCYDIVPTSSKLVVFDTTLQVKKAFFALVANGVRAAPLWESKKQSFVGMLTITDFINILHRYYKSPMVQIYELEEHKIETWRELYLQETFKPLVNISPDASLFDAVYSLIKNKIHRLPVIDPVSGNALYILTHKRILKFLQLFMSEMPKPAFMKKNLDELGIGTYHNIAFIHPDTPIIKALNIFVERRISALPVVDESGKVVDIYSKFDVINLAAEKTYNNLDITVTQALQHRSQYFEGVVKCSMLETLETIVDRIVKAEVHRLVVVNEADSIVGIISLSDILQALVLTPAGAKQKENESE", "length": 452, "header": "tr|F1NXI9-1|A0A8V1AEV9_CHICK Computationally mapped isoform of Protein kinase AMP-activated non-catalytic subunit gamma 2 OS=Gallus gallus OX=9031 GN=PRKAG2 PE=1 SV=3 CANONICAL=A0A8V1AEV9-1" }, "locus": { "chromosome": "2", "start_pos": 6397501, "end_pos": 6311256, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065786.1", "url": "https://www.ensembl.org/id/ENSGALT00010065786.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040052.1", "url": "https://www.ensembl.org/id/ENSGALP00010040052.1" } ] } }, { "isoform_ac": "F1NXL4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEV9/entry#F1NXL4-1", "sequence": { "sequence": "MGSTAMDTKKKDSSGSGRRGSSQKKLMLRVHIPDLSSFAMPFLDGDVENTDKNASRKVEESYSAGSPSKGIFSKGLQNRPSSPVSAPVRSKHSPGSPKTVFPFPYQESPPRSPRRMSFSGIFRSSSKESSPNSNPSTSPGGIKFFSRSRKTSGLSSSPSTPTQVTKQPTFPLESYKHEPERLETRIHCSSPPDTGQRFSLPPSQSAAKPPIMTPSPCATSKPAAAAAPAPSQLPAASEGMLEKLELEDEALEESESDIYVRFMRSHKCYDIVPTSSKLVVFDTTLQVKKAFFALVANGVRAAPLWESKKQSFVGMLTITDFINILHRYYKSPMVQIYELEEHKIETWRELYLQETFKPLVNISPDASLFDAVYSLIKNKIHRLPVIDPVSGNALYILTHKRILKFLQLFMSEMPKPAFMKKNLDELGIGTYHNIAFIHPDTPIIKALNIFVERRISALPVVDESGKVVDIYSKFDVINLAAEKTYNNLDITVTQALQHRSQYFEGVVKCSMLETLETIVDRIVKAEVHRLVVVNEADSIVGIISLSDILQALVLTPAGAKQKENESE", "length": 567, "header": "tr|F1NXL4-1|A0A8V1AEV9_CHICK Computationally mapped isoform of Protein kinase AMP-activated non-catalytic subunit gamma 2 OS=Gallus gallus OX=9031 GN=PRKAG2 PE=1 SV=3 CANONICAL=A0A8V1AEV9-1" }, "locus": { "chromosome": "2", "start_pos": 6492213, "end_pos": 6311256, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065799.1", "url": "https://www.ensembl.org/id/ENSGALT00010065799.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040065.1", "url": "https://www.ensembl.org/id/ENSGALP00010040065.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-1632852", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1632852", "resource": "Reactome", "description": "Macroautophagy" }, { "id": "R-GGA-380972", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-380972", "resource": "Reactome", "description": "Energy dependent regulation of mTOR by LKB1-AMPK" }, { "id": "R-GGA-5628897", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5628897", "resource": "Reactome", "description": "TP53 Regulates Metabolic Genes" }, { "id": "R-GGA-9931269", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9931269", "resource": "Reactome", "description": "AMPK-induced ERAD and lysosome mediated degradation of PD-L1(CD274)" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A140UHX4-1", "protein_name": "Protein kinase AMP-activated non-catalytic subunit gamma 2", "gene_name": "Prkag2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGSAAMDTKKKKEVSSPGGSSGKKNPSLKRRSLRVHIPDLSSFAMPLLDGDVENSEKHSSRKVDSPFSSGSPSRGLFSRGPQPRPSSPVSAPVRPKMSPGSPKTVFPFSYQESPPRSPRRMSFSGIFRSSSKESSPNSNPSTSPGGIRFFSRSRKTSSVSSSPSTPTQVTKQHPFPLESYKQEPERLESRIYASSSPPDTGQRFCLAFQSPVRLPLASPTHHAPLRTAALAAAPGPAEAGMLEKLEFQEEAEDSESGVYMRFMRSHKCYDIVPTSSKLVVFDTTLQVKKAFFALVANGVRAAPLWESKKQSFVGMLTITDFINILHRYYKSPMVQIYELEEHKIETWRELYLQETFKPLVNISPDASLFDAVYSLIKNKIHRLPVIDPISGNALYILTHKRILKFLQLFMSDMPKPAFMKQNLDELGIGTYHNIAFIHPNTPIIKALNIFVERRISALPVVDESGKVVDIYSKFDVINLAAEKTYNNLDITVTQALQHRSQYFEGVVKCSKLETLETIVDRIVRAEVHRLVVVNEADSIVGIISLSDILQALILTPAGAKQKETETE", "length": 567 }, "evidence": [ { "id": "A0A8V1AEV9", "url": "https://omabrowser.org/oma/group/A0A8V1AEV9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8M9PG44-1", "protein_name": "5'-AMP-activated protein kinase subunit gamma-2a isoform X1", "gene_name": "prkag2a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGSTAMDSKKKDEKKNTRKRISLRINMPDLSSFAMPFLEGDAEHACKDGARKGDLGCRSASPTKTFFSRGPFSRPSSPMSAPARTRTSPGSPKPIFSNHESSPKCSRRRSFTGIFRSSSKDSTNPSTSPVSIKLFSRTRKASGISSSPTTPTQLTKQTSAFLVEVSRNDTVHRSSSSPLDTGQPHSPPTAKPPPCPSSAPISTSRTVHGLSEDMLEKLDIEDEAVEHSESDIYMRFMKSHKCYDIVPTSSKLVVFDTTLQVKKAFFALVANGVRAAPLWETKKQSFVGMLTITDFINILHRYYKSPMVQIYELEEHKIETWRELYLQETFKPLVNISPDASIFDAVYSLIKNKIHRLPVIDPVSGNALYILTHKRILKFLQLFVCEMPKPAFMKQTLEELSIGTYNNIAFIHPDTPIIKALSIFVDRRVSALPVVDESGKVVDIYSKFDVINLAAEKTYNNLDISVTQALMHRSQYFEGVMKCNRLETLETIVDRIVKAEVHRLVVVDENGSIVGIVSLSDILQALVLNPAETDVIGFERQPADSVC", "length": 547 }, "evidence": [ { "id": "A0A8V1AEV9", "url": "https://omabrowser.org/oma/group/A0A8V1AEV9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q91WG5-1", "protein_name": "5'-AMP-activated protein kinase subunit gamma-2", "gene_name": "Prkag2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGSAAMDTKKKKEVSSPGGSSGKKNPSLKRRSLRVHIPDLSSFAMPLLDGDVENSEKHSSRKVDSPFSSGSPSRGLFSRGPQPRPSSPVSAPVRPKTSPGSPKTVFPFSYQESPPRSPRRMSFSGIFRSSSKESSPNSNPSTSPGGIRFFSRSRKTSSVSSSPSTPTQVTKQHPFPLESYKQEPERPESRIYASSSPPDTGQRFCLAFQSPARPPLASPTYHAPLRTAVLAAAPGPAEAGMLEKLEFQEEEDSESGVYMRFMRSHKCYDIVPTSSKLVVFDTTLQVKKAFFALVANGVRAAPLWESKKQSFVGMLTITDFINILHRYYKSPMVQIYELEEHKIETWRELYLQETFKPLVNISPDASLFDAVYSLIKNKIHRLPVIDPISGNALYILTHKRILKFLQLFMSDMPKPAFMKQNLDELGIGTYHNIAFIHPDTPIIKALNIFVERRISALPVVDESGKVVDIYSKFDVINLAAEKTYNNLDITVTQALQHRSQYFEGVVKCSKLETLETIVDRIVRAEVHRLVVVNEADSIVGIISLSDILQALILTPAGAKQKETETE", "length": 566 }, "evidence": [ { "id": "A0A8V1AEV9", "url": "https://omabrowser.org/oma/group/A0A8V1AEV9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9UGJ0-1", "protein_name": "5'-AMP-activated protein kinase subunit gamma-2", "gene_name": "PRKAG2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGSAVMDTKKKKDVSSPGGSGGKKNASQKRRSLRVHIPDLSSFAMPLLDGDLEGSGKHSSRKVDSPFGPGSPSKGFFSRGPQPRPSSPMSAPVRPKTSPGSPKTVFPFSYQESPPRSPRRMSFSGIFRSSSKESSPNSNPATSPGGIRFFSRSRKTSGLSSSPSTPTQVTKQHTFPLESYKHEPERLENRIYASSSPPDTGQRFCPSSFQSPTRPPLASPTHYAPSKAAALAAALGPAEAGMLEKLEFEDEAVEDSESGVYMRFMRSHKCYDIVPTSSKLVVFDTTLQVKKAFFALVANGVRAAPLWESKKQSFVGMLTITDFINILHRYYKSPMVQIYELEEHKIETWRELYLQETFKPLVNISPDASLFDAVYSLIKNKIHRLPVIDPISGNALYILTHKRILKFLQLFMSDMPKPAFMKQNLDELGIGTYHNIAFIHPDTPIIKALNIFVERRISALPVVDESGKVVDIYSKFDVINLAAEKTYNNLDITVTQALQHRSQYFEGVVKCNKLEILETIVDRIVRAEVHRLVVVNEADSIVGIISLSDILQALILTPAGAKQKETETE", "length": 569 }, "evidence": [ { "id": "A0A8V1AEV9", "url": "https://omabrowser.org/oma/group/A0A8V1AEV9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 8, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEV9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEV9" } ], "pmid": "" }, { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEV9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEV9" } ], "pmid": "" }, { "name": "cAMP-dependent protein kinase inhibitor activity", "id": "GO:0004862", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004862", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEV9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEV9" } ], "pmid": "" }, { "name": "phosphorylase kinase regulator activity", "id": "GO:0008607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008607", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEV9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEV9" } ], "pmid": "" }, { "name": "AMP binding", "id": "GO:0016208", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016208", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEV9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEV9" } ], "pmid": "" }, { "name": "protein kinase activator activity", "id": "GO:0030295", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030295", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEV9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEV9" } ], "pmid": "" }, { "name": "ADP binding", "id": "GO:0043531", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043531", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEV9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEV9" } ], "pmid": "" }, { "name": "protein kinase regulator activity", "id": "GO:0019887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019887", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEV9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEV9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEV9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEV9" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEV9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEV9" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEV9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEV9" } ], "pmid": "" }, { "name": "nucleotide-activated protein kinase complex", "id": "GO:0031588", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031588", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEV9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEV9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "fatty acid biosynthetic process", "id": "GO:0006633", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006633", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEV9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEV9" } ], "pmid": "" }, { "name": "regulation of glycolytic process", "id": "GO:0006110", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006110", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEV9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEV9" } ], "pmid": "" }, { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEV9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEV9" } ], "pmid": "" }, { "name": "glycogen metabolic process", "id": "GO:0005977", "url": 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[], "site_annotation": [ { "start_pos": 364, "end_pos": 366, "annotation": "n_glycosylation_sequon" }, { "start_pos": 567, "end_pos": 569, "annotation": "n_glycosylation_sequon" }, { "start_pos": 56, "end_pos": 58, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AEV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEV9" }, { "id": "PS51371", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51371" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CBS", "eco_id": "ECO_0000259", "start_pos": 276, "end_pos": 336, "start_aa": "Pro", "end_aa": "Met", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { 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##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052559.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015155252", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015155252" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AF41", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF41" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PIP5K1C", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF41", "locus": { "chromosome": "28", "start_pos": 1448023, "end_pos": 1417098, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028113", "url": "https://www.ensembl.org/id/ENSGALG00010028113" } ] } } ], "crossref": [ { "id": "A0A8V1AF41", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AF41", "database": 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"https://www.ebi.ac.uk/interpro/entry/IPR027484", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "DIYFFPD", "url": "https://omabrowser.org/oma/group/DIYFFPD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PWJ0", "url": "https://www.orthodb.org/?gene=A0A1D5PWJ0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A7D4", "url": "https://www.orthodb.org/?gene=A0A8V1A7D4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AF41", "url": "https://www.orthodb.org/?gene=A0A8V1AF41", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AJC3", "url": "https://www.orthodb.org/?gene=A0A8V1AJC3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1ND21", "url": "https://www.orthodb.org/?gene=F1ND21", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23086", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23086", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23086:SF26", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23086:SF26", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01504", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01504", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-1660499", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1660499", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-399955", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-399955", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-6811558", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6811558", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-8856828", "url": 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"https://www.uniprot.org/uniprotkb/A0A8V1AF41", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AF41-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF41-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJC3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJC3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJC3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJC3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1ND21", "url": "https://www.uniprot.org/uniprotkb/F1ND21", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1ND21-1", "url": "https://www.uniprot.org/uniprotkb/F1ND21-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MELEVPEEAEGSAVAGAGAITPEAGAGGPDAAGGLAPKKAAITEGPSLPGQPGQGKKIGHRSVDASGETTYKKTTSSTLKGAIQLGIGYTVGNLSSKPERDVLMQDFYVVESIFFPSEGSNLTPAHHYADFRFKTYAPVAFRYFRELFGIRPDDYLYSLCNEPLIELSNPGASGSLFYVTSDDEFIIKTVMHKEAEFLQKLLPGYYMNLNQNPRTLLPKFYGLYCVQSGGKNIRVVVMNNILPRVVKMHLKFDLKGSTYKRRASKKEKEKSSPTYKDLDFIQDMPEGLMLDADTFSALVKTLQRDCLVLESFKIMDYSLLLGVHNIDQQERERQSEGAHSTSDEKRPVGQKALYSTAMESIQGGAARGESIDTDDTMGGIPAVNGKGERLLLHVGIIDILQSYRFIKKLEHTWKALVHDGDTVSVHRPSFYAERFFKFMTNTVFRKNSSLKSSPSKKGRSALLAVKTPGPTAAFSASQLPSEKDETQYDLRAARSYPTLDDEAGRPDLLPCTPPSFEEATTASIATTLSSTSLSVPERSPSETSEQPRYRRRTHSSGQDGRSHEEVRVEEELQQISVELEPKCDVEIVAPEEHDKEEAASSACAIVMSTATIEVETASQASEPASQASDEDDVPVTDIYF", "length": 640, "header": "tr|A0A8V1AF41-1|A0A8V1AF41_CHICK Isoform 1 of Phosphatidylinositol-4-phosphate 5-kinase, type I, gamma OS=Gallus gallus OX=9031 GN=PIP5K1C PE=1 SV=1 CANONICAL=A0A8V1AF41-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PWJ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF41/entry#A0A1D5PWJ0-1", "sequence": { "sequence": "MELEVPEEAEGSAVAGAGAITPEAGAGGPDAAGGLAPKKAAITEGPSLPGQPGQGKKIGHRSVDASGETTYKKTTSSTLKGAIQLGIGYTVGNLSSKPERDVLMQDFYVVESIFFPSEGSNLTPAHHYADFRFKTYAPVAFRYFRELFGIRPDDYLYSLCNEPLIELSNPGASGSLFYVTSDDEFIIKTVMHKEAEFLQKLLPGYYMNLNQNPRTLLPKFYGLYCVQSGGKNIRVVVMNNILPRVVKMHLKFDLKGSTYKRRASKKEKEKSSPTYKDLDFIQDMPEGLMLDADTFSALVKTLQRDCLVLESFKIMDYSLLLGVHNIDQQERERQSEGAHSTSDEKRPVGQKALYSTAMESIQGGAARGESIDTDDTMGGIPAVNGKGERLLLHVGIIDILQSYRFIKKLEHTWKALVHDGDTVSVHRPSFYAERFFKFMTNTVFRKNSSLKSSPSKKGRSALLAVKTPGPTAAFSASQLPSEKDETQYDLRAARSYPTLDDEGRPDLLPCTPPSFEEATTASIATTLSSTSLSVPERSPSETSEQPRYRRRTHSSGQDGRSHEEVRVEEELQQISVELEPKCDVEIVAPEEHDKEEAASSACAIVMSTATIEVETASQASEPASQASDEDDVPVTDIYFADALGGAVEV", "length": 649, "header": "tr|A0A1D5PWJ0-1|A0A1D5PWJ0_CHICK Computationally mapped isoform of Phosphatidylinositol-4-phosphate 5-kinase, type I, gamma OS=Gallus gallus OX=9031 GN=PIP5K1C PE=1 SV=1 CANONICAL=A0A8V1AF41-1" }, "locus": { "chromosome": "28", "start_pos": 1443624, "end_pos": 1417279, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068113.1", "url": "https://www.ensembl.org/id/ENSGALT00010068113.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041856.1", "url": "https://www.ensembl.org/id/ENSGALP00010041856.1" } ] } }, { "isoform_ac": "A0A8V1A7D4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF41/entry#A0A8V1A7D4-1", "sequence": { "sequence": "MGPSLPGQPGQGKKIGHRSVDASGETTYKKTTSSTLKGAIQLGIGYTVGNLSSKPERDVLMQDFYVVESIFFPSEGSNLTPAHHYADFRFKTYAPVAFRYFRELFGIRPDDYLYSLCNEPLIELSNPGASGSLFYVTSDDEFIIKTVMHKEAEFLQKLLPGYYMNLNQNPRTLLPKFYGLYCVQSGGKNIRVVVMNNILPRVVKMHLKFDLKGSTYKRRASKKEKEKSSPTYKDLDFIQDMPEGLMLDADTFSALVKTLQRDCLVLESFKIMDYSLLLGVHNIDQQERERQSEGAHSTSDEKRPVGQKALYSTAMESIQGGAARGESIDTDDTMGGIPAVNGKGERLLLHVGIIDILQSYRFIKKLEHTWKALVHDGDTVSVHRPSFYAERFFKFMTNTVFRKNSSLKSSPSKKGRSALLAVKTPGPTAAFSASQLPSEKDETQYDLRAARSYPTLDDEGRPDLLPCTPPSFEEATTASIATTLSSTSLSVPERSPSETSEQPRYRRRTHSSGQDGRSHEEVRVEEELQQISVELEPKCDVEIVAPEEHDKEEAASSACAIVMSTATIEVETASQASEPASQASDEDDVPVTDIYFADALGGAVEV", "length": 606, "header": "tr|A0A8V1A7D4-1|A0A8V1AF41_CHICK Computationally mapped isoform of Phosphatidylinositol-4-phosphate 5-kinase, type I, gamma OS=Gallus gallus OX=9031 GN=PIP5K1C PE=1 SV=1 CANONICAL=A0A8V1AF41-1" }, "locus": { "chromosome": "28", "start_pos": 1443624, "end_pos": 1430665, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068111.1", "url": "https://www.ensembl.org/id/ENSGALT00010068111.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041854.1", "url": "https://www.ensembl.org/id/ENSGALP00010041854.1" } ] } }, { "isoform_ac": "A0A8V1AF41-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF41/entry#A0A8V1AF41-1", "sequence": { "sequence": "MELEVPEEAEGSAVAGAGAITPEAGAGGPDAAGGLAPKKAAITEGPSLPGQPGQGKKIGHRSVDASGETTYKKTTSSTLKGAIQLGIGYTVGNLSSKPERDVLMQDFYVVESIFFPSEGSNLTPAHHYADFRFKTYAPVAFRYFRELFGIRPDDYLYSLCNEPLIELSNPGASGSLFYVTSDDEFIIKTVMHKEAEFLQKLLPGYYMNLNQNPRTLLPKFYGLYCVQSGGKNIRVVVMNNILPRVVKMHLKFDLKGSTYKRRASKKEKEKSSPTYKDLDFIQDMPEGLMLDADTFSALVKTLQRDCLVLESFKIMDYSLLLGVHNIDQQERERQSEGAHSTSDEKRPVGQKALYSTAMESIQGGAARGESIDTDDTMGGIPAVNGKGERLLLHVGIIDILQSYRFIKKLEHTWKALVHDGDTVSVHRPSFYAERFFKFMTNTVFRKNSSLKSSPSKKGRSALLAVKTPGPTAAFSASQLPSEKDETQYDLRAARSYPTLDDEAGRPDLLPCTPPSFEEATTASIATTLSSTSLSVPERSPSETSEQPRYRRRTHSSGQDGRSHEEVRVEEELQQISVELEPKCDVEIVAPEEHDKEEAASSACAIVMSTATIEVETASQASEPASQASDEDDVPVTDIYF", "length": 640, "header": "tr|A0A8V1AF41-1|A0A8V1AF41_CHICK Isoform 1 of Phosphatidylinositol-4-phosphate 5-kinase, type I, gamma OS=Gallus gallus OX=9031 GN=PIP5K1C PE=1 SV=1 CANONICAL=A0A8V1AF41-1" }, "locus": { "chromosome": "28", "start_pos": 1443174, "end_pos": 1417279, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068115.1", "url": "https://www.ensembl.org/id/ENSGALT00010068115.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041858.1", "url": "https://www.ensembl.org/id/ENSGALP00010041858.1" } ] } }, { "isoform_ac": "A0A8V1AJC3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF41/entry#A0A8V1AJC3-1", "sequence": { "sequence": "MELEVPEEAEGSAVAGAGAITPEAGAGGPDAAGGLAPKKAAITEGPSLPGQPGQGKKIGHRSVDASGETTYKKTTSSTLKGAIQLGIGYTVGNLSSKPERDVLMQDFYVVESIFFPSEGSNLTPAHHYADFRFKTYAPVAFRYFRELFGIRPDDYLYSLCNEPLIELSNPGASGSLFYVTSDDEFIIKTVMHKEAEFLQKLLPGYYMNLNQNPRTLLPKFYGLYCVQSGGKNIRVVVMNNILPRVVKMHLKFDLKGSTYKRRASKKEKEKSSPTYKDLDFIQDMPEGLMLDADTFSALVKTLQRDCLVLESFKIMDYSLLLGVHNIDQQERERQSEGAHSTSDEKRPVGQKALYSTAMESIQGGAARGESIDTDDTMGGIPAVNGKGERLLLHVGIIDILQSYRFIKKLEHTWKALVHDGDTVSVHRPSFYAERFFKFMTNTVFRKNSSLKSSPSKKGRSALLAVKTPGPTAAFSASQLPSEKDETQYDLRAARSYPTLDDEGRPDLLPCTPPSFEEATTASIATTLSSTSLSVPERSPSETSEQPRYRRRTHSSGQDGRSHEEVRVEEELQQISVELEPKCDVEIVAPEEHDKEEAASSACAIVMSTATIEVETASQASEPASQASDEDDVPVTDIYFVRYPLPGPLGMERRCVDEAVICFRQWGVWGSVCPTLC", "length": 676, "header": "tr|A0A8V1AJC3-1|A0A8V1AF41_CHICK Computationally mapped isoform of Phosphatidylinositol-4-phosphate 5-kinase, type I, gamma OS=Gallus gallus OX=9031 GN=PIP5K1C PE=1 SV=1 CANONICAL=A0A8V1AF41-1" }, "locus": { "chromosome": "28", "start_pos": 1443285, "end_pos": 1417279, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068112.1", "url": "https://www.ensembl.org/id/ENSGALT00010068112.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041855.1", "url": "https://www.ensembl.org/id/ENSGALP00010041855.1" } ] } }, { "isoform_ac": "F1ND21-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF41/entry#F1ND21-1", "sequence": { "sequence": "MELEVPEEAEGSAVAGAGAITPEAGAGGPDAAGGLAPKKAAITEGPSLPGQPGQGKKIGHRSVDASGETTYKKTTSSTLKGAIQLGIGYTVGNLSSKPERDVLMQDFYVVESIFFPSEGSNLTPAHHYADFRFKTYAPVAFRYFRELFGIRPDDYLYSLCNEPLIELSNPGASGSLFYVTSDDEFIIKTVMHKEAEFLQKLLPGYYMNLNQNPRTLLPKFYGLYCVQSGGKNIRVVVMNNILPRVVKMHLKFDLKGSTYKRRASKKEKEKSSPTYKDLDFIQDMPEGLMLDADTFSALVKTLQRDCLVLESFKIMDYSLLLGVHNIDQQERERQSEGAHSTSDEKRPVGQKALYSTAMESIQGGAARGESIDTDDTMGGIPAVNGKGERLLLHVGIIDILQSYRFIKKLEHTWKALVHDGDTVSVHRPSFYAERFFKFMTNTVFRKNSSLKSSPSKKGRSALLAVKTPGPTAAFSASQLPSEKDETQYDLRAARSYPTLDDEGRPDLLPCTPPSFEEATTASIATTLSSTSLSVPERSPSETSEQPRYRRRTHSSGQDGRSHEEVRVEEELQQISVELEPKCDVEIVAPEEHDKEEAASSACAIVMSTATIEVETASQASEPASQASDEDDVPVTDIYFPTDERSWVYSPLHYSAQLHSVSDEESDT", "length": 667, "header": "tr|F1ND21-1|A0A8V1AF41_CHICK Computationally mapped isoform of Phosphatidylinositol-4-phosphate 5-kinase, type I, gamma OS=Gallus gallus OX=9031 GN=PIP5K1C PE=1 SV=3 CANONICAL=A0A8V1AF41-1" }, "locus": { "chromosome": "28", "start_pos": 1447227, "end_pos": 1417279, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068118.1", "url": "https://www.ensembl.org/id/ENSGALT00010068118.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041861.1", "url": "https://www.ensembl.org/id/ENSGALP00010041861.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 471, "start_aa": "Thr", "end_pos": 471, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr471", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-GGA-1660499", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1660499", "resource": "Reactome", "description": "Synthesis of PIPs at the plasma membrane" }, { "id": "R-GGA-399955", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-399955", "resource": "Reactome", "description": "SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion" }, { "id": "R-GGA-6811558", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6811558", "resource": "Reactome", "description": "PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling" }, { "id": "R-GGA-8856828", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8856828", "resource": "Reactome", "description": "Clathrin-mediated endocytosis" }, { "id": "R-GGA-9768727", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9768727", "resource": "Reactome", "description": "Regulation of CDH1 posttranslational processing and trafficking to plasma membrane" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1MBL1-1", "protein_name": "Phosphatidylinositol-4-phosphate 5-kinase type 1 gamma", "gene_name": "PIP5K1C", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MELEVPDEAESAEAGAVTSEAAWAAESGATAGSAQKKTPAEVPLMTGQPGPGHGKKLGHRGVDASGETTYKKTTSSTLKGAIQLGIGYTVGNLSSKPERDVLMQDFYVVESIFFPSEGSNLTPAHHFQDFRFKTYAPVAFRYFRELFGIRPDDYLYSLCNEPLIELSNPGASGSLFYVTSDDEFIIKTVMHKEAEFLQKLLPGYYMNLNQNPRTLLPKFYGLYCVQSGGKNIRVVVMNNVLPRVVKMHLKFDLKGSTYKRRASKKEKEKSIPTYKDLDFIQDMPEGLMLDADTFSALVKTLQRDCLVLESFKIMDYSLLLGVHNIDQQERERQAEGAQSTADEKRPLGQKALYSTAMESIQGGAARGEAIETDDTMGGIPAVNGRGERLLLHIGIIDILQSYRFIKKLEHTWKALVHDGDTVSVHRPSFYAERFFKFMSNTVFRKNSSLKSSPSKKGRGALLAVKPLGPTAAFSASQIPSEREDAQYDLRGARSYPTLEDEGRPDLLPCTPPSFEEATTASIATTLSSTSLSIPERSPSESSEQPRYRRRTQSSGQDGRPQEETHAEEDLQQITVQVEPACSVEIVVPKEEDAGEGVSPACASAAVEAETASQASEPASQASEPASQASDEEDAPATDIYFFTDGRYWIYSPRHRRLRAVTLSSSGTPTDERSWVYSPLHYSTQAQPASDGESDT", "length": 695 }, "evidence": [ { "id": "A0A8V1AF41", "url": "https://omabrowser.org/oma/group/A0A8V1AF41/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A8M3B5L6-1", "protein_name": "Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma isoform X1", "gene_name": "pip5k1ca", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEAAAAEGAASLSEAGDGSPLSGATASEDAGSADDVDADSISKKAFITEMPSSSGLPSHGKKIGHRGVDASGETTYKKTTSSALKGAIQLGIGYTVGNLSSKPERDVLMQDFYVVESIFFPSEGSNLTPAHHFPDFRFKTYAPVAFRYFRELFGIRPDDYLYSLCNEPLIELSNPGASGSVFYLTKDDEFIIKTVMHKEAEFLQKLLPGYYMNLNQNPRTLLPKFFGLYCVQSGGKNIRMVVMNNVLPRVVRMHLKYDLKGSTYKRRASKKEREKAKPTFKDLDFMQELPDGLMLDTDTYNALVKTLQRDCLVLESFKIMDYSLLLGVHNIDQAAKEQQMEGSQGNSDEKRPLAQKALYTTAMESIQGASACGEGIDTDDTMGGIPAVNGRGERLLLYIGIIDILQSYRLIKKLEHTWKALVHDGDTVSVHRPSFYADRFLRFMSSTVFRKTSSLKSSPSKRGRGGLAVGKYCGPGAAWSASQLPFMRDENIYDLRGARSFPTLEDDGRADVLPCTPPSFEEATTASIATTLSSTTSLSIPERSPSDTSEHPRYRRHTQSSHEETMQDEDQQTITVEVEVEGRYDSEPTLVAPQVSPEISEAAETIPEASSSSVPASPRIVVESDGGSQASGCTSRASVDEEDDVPITDIYFFCDGSVHVCPPATHRRRHIPPEDKSWVYSPLHFSSGPKTLPEDEGESET", "length": 701 }, "evidence": [ { "id": "A0A8V1AF41", "url": "https://omabrowser.org/oma/group/A0A8V1AF41/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "O60331-1", "protein_name": "Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma", "gene_name": "PIP5K1C", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MELEVPDEAESAEAGAVPSEAAWAAESGAAAGLAQKKAAPTEVLSMTAQPGPGHGKKLGHRGVDASGETTYKKTTSSTLKGAIQLGIGYTVGHLSSKPERDVLMQDFYVVESIFFPSEGSNLTPAHHFQDFRFKTYAPVAFRYFRELFGIRPDDYLYSLCNEPLIELSNPGASGSLFYVTSDDEFIIKTVMHKEAEFLQKLLPGYYMNLNQNPRTLLPKFYGLYCVQSGGKNIRVVVMNNILPRVVKMHLKFDLKGSTYKRRASKKEKEKSFPTYKDLDFMQDMPEGLLLDADTFSALVKTLQRDCLVLESFKIMDYSLLLGVHNIDQHERERQAQGAQSTSDEKRPVGQKALYSTAMESIQGGAARGEAIESDDTMGGIPAVNGRGERLLLHIGIIDILQSYRFIKKLEHTWKALVHDGDTVSVHRPSFYAERFFKFMSNTVFRKNSSLKSSPSKKGRGGALLAVKPLGPTAAFSASQIPSEREEAQYDLRGARSYPTLEDEGRPDLLPCTPPSFEEATTASIATTLSSTSLSIPERSPSETSEQPRYRRRTQSSGQDGRPQEEPPAEEDLQQITVQVEPACSVEIVVPKEEDAGVEASPAGASAAVEVETASQASDEEGAPASQASDEEDAPATDIYFPTDERSWVYSPLHYSAQAPPASDGESDT", "length": 668 }, "evidence": [ { "id": "A0A8V1AF41", "url": "https://omabrowser.org/oma/group/A0A8V1AF41/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "O70161-1", "protein_name": "Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma", "gene_name": "Pip5k1c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MELEVPDEAESAEAGAVTAEAAWSAESGAAAGMTQKKAGLAEAPLVTGQPGPGHGKKLGHRGVDASGETTYKKTTSSTLKGAIQLGIGYTVGNLSSKPERDVLMQDFYVVESIFFPSEGSNLTPAHHFQDFRFKTYAPVAFRYFRELFGIRPDDYLYSLCNEPLIELSNPGASGSVFYVTSDDEFIIKTVMHKEAEFLQKLLPGYYMNLNQNPRTLLPKFYGLYCVQSGGKNIRVVVMNNVLPRVVKMHLKFDLKGSTYKRRASKKEKEKSLPTYKDLDFMQDMPEGLLLDSDTFGALVKTLQRDCLVLESFKIMDYSLLLGVHNIDQQERERQAEGAQSKADEKRPVAQKALYSTAMESIQGGAARGEAIETDDTMGGIPAVNGRGERLLLHIGIIDILQSYRFIKKLEHTWKALVHDGDTVSVHRPSFYAERFFKFMSSTVFRKSSSLKSSPSKKGRGALLAVKPLGPTAAFSASQIPSEREDVQYDLRGARSYPTLEDEGRPDLLPCTPPSFEEATTASIATTLSSTSLSIPERSPSDTSEQPRYRRRTQSSGQDGRPQEEPHAEDLQKITVQVEPVCGVGVVPKEEGAGVEVPPCGASAAASVEIDAASQASEPASQASDEEDAPSTDIYFPTDERSWVYSPLHYSARPASDGESDT", "length": 661 }, "evidence": [ { "id": "A0A8V1AF41", "url": "https://omabrowser.org/oma/group/A0A8V1AF41/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5I6B8-1", "protein_name": "Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma", "gene_name": "Pip5k1c", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MELEVPDEAESAEAGAVTAEAAWSAESGAAAGMTQKKAILAEAPLVTGQPGPGHGKKLGHRGVDASGETTYKKTTSSTLKGAIQLGIGYTVGNLSSKPERDVLMQDFYVVESIFFPSEGSNLTPAHHFQDFRFKTYAPVAFRYFRELFGIRPDDYLYSLCNEPLIELSNPGASGSVFYVTSDDEFIIKTVMHKEAEFLQKLLPGYYMNLNQNPRTLLPKFYGLYCVQSGGKNIRVVVMNNVLPRVVKMHLKFDLKGSTYKRRASKKEKEKSLPTYKDLDFMQDMPEGLLLDSDTFGALVKTLQRDCLVLESFKIMDYSLLLGVHNIDQQERERQAEGAQSKADEKRPVAQKALYSTARESIQGGAARGEAIETDDTMGGIPAVNGRGERLLLHIGIIDILQSYRFIKKLEHTWKALVHDGDTVSVHRPSFYAERFFKFMSSTVFRKSSSLKSSPSKKGRGALLAVKPLGPTAAFSASQIPSEREDVQYDLRGARSYPTLEDEGRPDLLPCTPPSFEEATTASIATTLSSTSLSIPERSPSDTSEQPRYRRRTQSSGQDGRPQEELHAEDLQKITVQVEPVCGVGVVVPKEQGAGVEVPPSGASAAATVEVDAASQASEPASQASDEEDAPSTDIYFFAHGRYWLFSPRRRRLRAVTPSHTGAPTDGRSWVYSPLHYSARPASDGESDT", "length": 688 }, "evidence": [ { "id": "A0A8V1AF41", "url": "https://omabrowser.org/oma/group/A0A8V1AF41/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AF41", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF41" } ], "pmid": "" }, { "name": "1-phosphatidylinositol-4-phosphate 5-kinase activity", "id": "GO:0016308", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016308", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AF41", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF41" } ], "pmid": "" }, { "name": "phosphatidylinositol kinase activity", "id": "GO:0052742", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0052742", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AF41", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF41" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AF41", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF41" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AF41", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF41" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AF41", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF41" } ], "pmid": "" }, { "name": "endosome membrane", "id": "GO:0010008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010008", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AF41", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF41" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AF41", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF41" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "phosphatidylinositol phosphate biosynthetic process", "id": "GO:0046854", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046854", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AF41", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF41" } ], "pmid": "" }, { "name": "phosphatidylinositol metabolic process", "id": "GO:0046488", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046488", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AF41", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF41" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 121, "end_pos": 123, "annotation": "n_glycosylation_sequon" }, { "start_pos": 447, "end_pos": 449, "annotation": "n_glycosylation_sequon" }, { "start_pos": 93, "end_pos": 95, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AF41", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF41" }, { "id": "PS51455", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51455" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PIPK", "eco_id": "ECO_0000259", "start_pos": 75, "end_pos": 443, "start_aa": "Thr", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 471 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 121, "end_pos": 123 }, { "start_pos": 447, "end_pos": 449 }, { "start_pos": 93, "end_pos": 95 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": 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"sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AFP7-1", "uniprot_ac": "A0A8V1AFP7", "uniprot_id": "A0A8V1AFP7_CHICK", "mass": { "chemical_mass": 31770.0, "monoisotopic_mass": 31770.0 }, "refseq": {}, "gene_names": [ { "name": "METRNL", "type": "recommended", "evidence": [ { "id": "A0A8V1AFP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFP7" } ] } ], "protein_names": [ { "name": "Meteorin-like protein", "type": "recommended", "evidence": [ { "id": "A0A8V1AFP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFP7/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFP7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFP7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "METRNL", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFP7", "locus": { "chromosome": "18", "start_pos": 3711298, "end_pos": 3732472, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029946", "url": "https://www.ensembl.org/id/ENSGALG00010029946" } ] } } ], "crossref": [ { "id": "A0A8V1AFP7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AFP7", "database": "AlphaFoldDB", "categories": [] }, { "id": "417332", "url": "https://www.ncbi.nlm.nih.gov/gene/417332", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR008993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051998", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051998", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:417332", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417332", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ISFCQYS", "url": "https://omabrowser.org/oma/group/ISFCQYS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AFP7", "url": "https://www.orthodb.org/?gene=A0A8V1AFP7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AQB6", "url": "https://www.orthodb.org/?gene=A0A8V1AQB6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR28593", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28593", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR28593:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28593:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF27640", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27640", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1AFP7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFP7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFP7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFP7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AQB6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AQB6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AQB6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AQB6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPLFTSFLNSFGLLTIDASLIPANPLQGESVRGLTHESHKKDVEQVYLRCSEGSIEWMYPTGALIVNLRPNTSPASYKHLTVCIKPFKDSAGANIYLEKTGELKLLVRDGERSPSKVYCFGYDQGGLFVEATPQQDISRKITGFQYELMSRGIASDLHTVSAPCRPCSDTEVLLAVCTSDFVIRGSIQDVTNEAEEQESVIHVGVNKLYRQKSKVFQLTGESGNWRGQIKTLLECGVRPGDGDFLFTGRMHFGEARLGCAPRFKDFQRMYKEAKDKGLNPCEIGPD", "length": 286, "header": "tr|A0A8V1AFP7-1|A0A8V1AFP7_CHICK Isoform 1 of Meteorin-like protein OS=Gallus gallus OX=9031 GN=METRNL PE=3 SV=1 CANONICAL=A0A8V1AFP7-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AFP7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFP7/entry#A0A8V1AFP7-1", "sequence": { "sequence": "MPLFTSFLNSFGLLTIDASLIPANPLQGESVRGLTHESHKKDVEQVYLRCSEGSIEWMYPTGALIVNLRPNTSPASYKHLTVCIKPFKDSAGANIYLEKTGELKLLVRDGERSPSKVYCFGYDQGGLFVEATPQQDISRKITGFQYELMSRGIASDLHTVSAPCRPCSDTEVLLAVCTSDFVIRGSIQDVTNEAEEQESVIHVGVNKLYRQKSKVFQLTGESGNWRGQIKTLLECGVRPGDGDFLFTGRMHFGEARLGCAPRFKDFQRMYKEAKDKGLNPCEIGPD", "length": 286, "header": "tr|A0A8V1AFP7-1|A0A8V1AFP7_CHICK Isoform 1 of Meteorin-like protein OS=Gallus gallus OX=9031 GN=METRNL PE=3 SV=1 CANONICAL=A0A8V1AFP7-1" }, "locus": { "chromosome": "18", "start_pos": 3731352, "end_pos": 3711988, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010072376.1", "url": "https://www.ensembl.org/id/ENSGALT00010072376.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044843.1", "url": "https://www.ensembl.org/id/ENSGALP00010044843.1" } ] } }, { "isoform_ac": "A0A8V1AQB6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFP7/entry#A0A8V1AQB6-1", "sequence": { "sequence": "MRSAPAAGLLPLLLGLRLLLGGGAEAQYSSDLCNWKGSGLTHESHKKDVEQVYLRCSEGSIEWMYPTGALIVNLRPNTSPASYKHLTVCIKPFKDSAGANIYLEKTGELKLLVRDGERSPSKVYCFGYDQGGLFVEATPQQDISRKITGFQYELMSRGIASDLHTVSAPCRPCSDTEVLLAVCTSDFVIRGSIQDVTNEAEEQESVIHVGVNKLYRQKSKVFQLTGESGNWRGQIKTLLECGVRPGDGDFLFTGRMHFGEARLGCAPRFKDFQRMYKEAKDKGLNPCEIGPD", "length": 292, "header": "tr|A0A8V1AQB6-1|A0A8V1AFP7_CHICK Computationally mapped isoform of Meteorin-like protein OS=Gallus gallus OX=9031 GN=METRNL PE=3 SV=1 CANONICAL=A0A8V1AFP7-1" }, "locus": { "chromosome": "18", "start_pos": 3732307, "end_pos": 3711988, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010072377.1", "url": "https://www.ensembl.org/id/ENSGALT00010072377.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044844.1", "url": "https://www.ensembl.org/id/ENSGALP00010044844.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:417332", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417332", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "G3X6G7-1", "protein_name": "Meteorin-like protein", "gene_name": "METRNL", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRGATRAAGGRAGQLWPRPPAPGPGPPPLLLLLAVLLGGAGAQYSSDLCSWKGSGLTHEAHRKEVEQVYLRCSAGTVEWMYPTGALIVNLRPNTFSPSRNLTLCIKPLRGSSGANIYLEKTGELKLLVRDGDLGPGQAPCFGFEQGGLFVEATPQQDISRRTTGFQYELTSRRTGPDLHALLAPCRPCSHTEVLLAVCTSDFVVRGSIQKVTHEPERQESAIHLNVSRLYRQKSRVFRPAPEGEGGGWRGRVSTLLECGVRPGHGEFLFTGHMHFGEAWLGCAPRFKDFQRMYRDAEERGLNPCEMGTE", "length": 309 }, "evidence": [ { "id": "A0A8V1AFP7", "url": "https://omabrowser.org/oma/group/A0A8V1AFP7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q5RJL6-1", "protein_name": "Meteorin-like protein", "gene_name": "Metrnl", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRGVVWAARRRAGQQWPRSPGPGPGPPPPPPLLLLLLLLLGGASAQYSSDLCSWKGSGLTREAHSKEVEQVYLRCSAGSVEWMYPTGALIVNLRPNTFSPAQNLTVCIKPFRDSSGANIYLEKTGELRLLVRDVRGEPGQVQCFSLEQGGLFVEATPQQDISRRTTGFQYELMSGQRGLDLHVLSAPCRPCSDTEVLLAICTSDFVVRGFIEDVTHVPEQQVSVIHLRVSRLHRQKSRVFQPAPEDSGHWLGHVTTLLQCGVRPGHGEFLFTGHVHFGEAQLGCAPRFSDFQKMYRKAEERGINPCEINME", "length": 311 }, "evidence": [ { "id": "A0A8V1AFP7", "url": "https://omabrowser.org/oma/group/A0A8V1AFP7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q641Q3-1", "protein_name": "Meteorin-like protein", "gene_name": "METRNL", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRGAARAAWGRAGQPWPRPPAPGPPPPPLPLLLLLLAGLLGGAGAQYSSDRCSWKGSGLTHEAHRKEVEQVYLRCAAGAVEWMYPTGALIVNLRPNTFSPARHLTVCIRSFTDSSGANIYLEKTGELRLLVPDGDGRPGRVQCFGLEQGGLFVEATPQQDIGRRTTGFQYELVRRHRASDLHELSAPCRPCSDTEVLLAVCTSDFAVRGSIQQVTHEPERQDSAIHLRVSRLYRQKSRVFEPVPEGDGHWQGRVRTLLECGVRPGHGDFLFTGHMHFGEARLGCAPRFKDFQRMYRDAQERGLNPCEVGTD", "length": 311 }, "evidence": [ { "id": "A0A8V1AFP7", "url": "https://omabrowser.org/oma/group/A0A8V1AFP7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8VE43-1", "protein_name": "Meteorin-like protein", "gene_name": "Metrnl", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRGAVWAARRRAGQQWPRSPGPGPGPPPPPPLLLLLLLLLGGASAQYSSDLCSWKGSGLTREARSKEVEQVYLRCSAGSVEWMYPTGALIVNLRPNTFSPAQNLTVCIKPFRDSSGANIYLEKTGELRLLVRDIRGEPGQVQCFSLEQGGLFVEATPQQDISRRTTGFQYELMSGQRGLDLHVLSAPCRPCSDTEVLLAICTSDFVVRGFIEDVTHVPEQQVSVIYLRVNRLHRQKSRVFQPAPEDSGHWLGHVTTLLQCGVRPGHGEFLFTGHVHFGEAQLGCAPRFSDFQRMYRKAEEMGINPCEINME", "length": 311 }, "evidence": [ { "id": "A0A8V1AFP7", "url": "https://omabrowser.org/oma/group/A0A8V1AFP7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFP7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFP7" } ], "pmid": "" }, { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFP7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFP7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "response to cold", "id": "GO:0009409", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009409", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFP7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFP7" } ], "pmid": "" }, { "name": "negative regulation of inflammatory response", "id": "GO:0050728", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050728", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFP7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFP7" } ], "pmid": "" }, { "name": "energy homeostasis", "id": "GO:0097009", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097009", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFP7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFP7" } ], "pmid": "" }, { "name": "fat cell differentiation", "id": "GO:0045444", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045444", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFP7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFP7" } ], "pmid": "" }, { "name": "response to muscle activity", "id": "GO:0014850", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014850", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFP7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFP7" } ], "pmid": "" }, { "name": "positive regulation of brown fat cell differentiation", "id": "GO:0090336", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090336", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFP7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFP7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "hormone activity", "id": "GO:0005179", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005179", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFP7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFP7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 71, "end_pos": 73, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], 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], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZSZ2-1", "uniprot_ac": "A0A8V0ZSZ2", "uniprot_id": "A0A8V0ZSZ2_CHICK", "mass": { "chemical_mass": 130449.0, "monoisotopic_mass": 130449.0 }, "refseq": {}, "gene_names": [ { "name": "ITGA7", "type": "recommended", "evidence": [ { "id": "A0A8V0ZSZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSZ2" } ] } ], "protein_names": [ { "name": "Integrin subunit alpha 7", "type": "synonym", "evidence": [ { "id": "A0A8V0ZSZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSZ2/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSZ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSZ2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ITGA7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSZ2", "locus": { "chromosome": "34", "start_pos": 1835159, "end_pos": 1821137, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022950", "url": "https://www.ensembl.org/id/ENSGALG00010022950" } ] } } ], "crossref": [ { "id": "A0A8V0ZSZ2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZSZ2", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR000413", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000413", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013519", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013519", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013649", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013649", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018184", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018184", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028994", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028994", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032695", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032695", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048285", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048285", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048286", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048286", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZKR7", "url": "https://www.orthodb.org/?gene=A0A8V0ZKR7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZR46", "url": "https://www.orthodb.org/?gene=A0A8V0ZR46", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZSZ2", "url": "https://www.orthodb.org/?gene=A0A8V0ZSZ2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZT12", "url": "https://www.orthodb.org/?gene=A0A8V0ZT12", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23220", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23220", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23220:SF90", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23220:SF90", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08441", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08441", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF20805", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20805", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF20806", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20806", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-3000178", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3000178", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZKR7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKR7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKR7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKR7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZR46", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR46", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZR46-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR46-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZSZ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSZ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZSZ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSZ2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZT12", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT12", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZT12-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT12-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQRTAQRALAQSAIAAAAEERRARSERSAVSPCGVTALCHCHRCVFLPPHPPCCVTAPCPRAAVTPHGPTGRRGGGGGGGARFAGTARAVGGPQRSGAVRCGAGMAGLSLPGLFVPWLCLSALLGGGSLALIRGSHPCRLLVGAPQAPALPSQAANRTGGLFACPLTSEPSDCWRVPIDEGVDLQRESKENQWLGVSVKSQGAGGKIVTCAHRYEARNRVQQPLETRDVIGRCFVLSQDLQVHDELDGGEWKFCEGRPQGHDRFGFCQQGLAAAFSPDQHYVLFGAVPPVPFSPILGSAGNMRVELLNQSSLDLLRYDDGPYEAGGEKDQDPSLIPVPANSYFGLLFVTNIDSSDPDQLVYKSPDPSEKVPGAAGDVPQNSYLGFSVDSGAGLTRRRELSFVSGAPRANHTGAVVILRRDSAHRLVPEAVLPGEQLTSAFGYALAVLDLNTGWTWWWGAPHFFERKAEIGGAAYVYINPAGHWDAATPLRLTGTHGSMFGIALGTAGDLNLDGFEGEGLGCGRGLWCPHCSQCHGCSRPQVLDGEGVGVRTFGYALSGGVDVDGNLYPDLLVGSLSDAVVLYRARPVVYISRNVSLLPANIDLEQSNCQHQEGICVDVQACFSYTATPASYSPPLGDTAPSLSHHGDGWVTPPRVTFLGRRPSDPEHQISHTVELPRQHARTCTTATFQLQDSIRDKLRPITVTLAYGIQGAGTPRHSRSATLPPLPPVLSPQQPSSHRTEVHFLNNLQLRFQFCTRLGDADFLPLPKGADGTAIFAMSDQKDVALEIHVTNMPSDPTEPQRDGDDAHEAVLTARFPQELPYSAVRPYDGRTAPDKPVVCLANQNGSQVECELGNPMKRGAQVRFYLILSTLGITLQTTDLAVELALSTISEQPTLEPVVARARVVIELPLSVTGVAVPPRLFFGGTVRGESAVRRESHVGSAVLFEVTVSNRGPSLKTLGSAFLTLLWPHELSNGKWLLYPLQLELLAAPGLRTVCSPAANPLRLALEPPGEAEVTEEAAVESWWVPAPAERRRNVTLDCAQGTARCMAFRCPLYSFERAAVLTARGRLWNSTFLEEYLAVTSVELIVRASVSVTSSIKNLVLKDASTQIPVTIYLDPGVAVAGGVPWWVILLAVLAGILVLALLIFILWKLGFFRRARYVPPAVPQYHAVKIPREERQQYREEKMGTIQRKEWAVNWSEPSDGHVTPSSA", "length": 1212, "header": "tr|A0A8V0ZSZ2-1|A0A8V0ZSZ2_CHICK Isoform 1 of Integrin subunit alpha 7 OS=Gallus gallus OX=9031 GN=ITGA7 PE=3 SV=1 CANONICAL=A0A8V0ZSZ2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZKR7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSZ2/entry#A0A8V0ZKR7-1", "sequence": { "sequence": "MQRTAQRALAQSAIAAAAEERRARSERSAVSPCGVTALCHCHRCVFLPPHPPCCVTAPCPRAAVTPHGPTGRRGGGGGGGARFAGTARAVGGPQRSGAVRCGAGMAGLSLPGLFVPWLCLSALLGGGSLALIRGSHPCRLLVGAPQAPALPSQAANRTGGLFACPLTSEPSDCWRVPIDEGVDLQRESKENQWLGVSVKSQGAGGKIVTCAHRYEARNRVQQPLETRDVIGRCFVLSQDLQVHDELDGGEWKFCEGRPQGHDRFGFCQQGLAAAFSPDQHYVLFGAPRHLQLEGSDPDQLVYKSPDPSEKVPGAAGDVPQNSYLGFSVDSGAGLTRRRELSFVSGAPRANHTGAVVILRRDSAHRLVPEAVLPGEQLTSAFGYALAVLDLNTGWTWWWGAPHFFERKAEIGGAAYVYINPAGHWDAATPLRLTGTHGSMFGIALGTAGDLNLDGFEGEGLGCGRGLWCPHCSQCHGCSRPQVLDGEGVGVRTFGYALSGGVDVDGNLYPDLLVGSLSDAVVLYRARPVVYISRNVSLLPANIDLEQSNCQHQEGICVDVQACFSYTATPASYSPPLGDTAPSLSHHGDGWVTPPRVTFLGRRPSDPEHQISHTVELPRQHARTCTTATFQLQDSIRDKLRPITVTLAYGIQGAGTPRHSRSATLPPLPPVLSPQQPSSHRTEVHFLNNLQLRFQFCTRLGDADFLPLPKGADGTAIFAMSDQKDVALEIHVTNMPSDPTEPQRDGDDAHEAVLTARFPQELPYSAVRPYDGRTAPDKPVVCLANQNGSQVECELGNPMKRGAQVRFYLILSTLGITLQTTDLAVELALSTISEQPTLEPVVARARVVIELPLSVTGVAVPPRLFFGGTVRGESAVRRESHVGSAVLFEVTVSNRGPSLKTLGSAFLTLLWPHELSNGKWLLYPLQLELLAAPGLRTVCSPAANPLRLALEPPGEAEVTEEAAVESWWVPAPAERRRNVTLDCAQGTARCMAFRCPLYSFERAAVLTARGRLWNSTFLEEYLAVTSVELIVRASVSVTSSIKNLVLKDASTQIPVTIYLDPGVAVAGGVPWWVILLAVLAGILVLALLIFILWKLGFFRRARYVPPAVPQYHAVKIPREERQQYREEKMGTIQRKEWAVNWSEPSDGHVTPSSA", "length": 1153, "header": "tr|A0A8V0ZKR7-1|A0A8V0ZSZ2_CHICK Computationally mapped isoform of Integrin subunit alpha 7 OS=Gallus gallus OX=9031 GN=ITGA7 PE=3 SV=1 CANONICAL=A0A8V0ZSZ2-1" }, "locus": { "chromosome": "34", "start_pos": 1834265, "end_pos": 1821137, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056141.1", "url": "https://www.ensembl.org/id/ENSGALT00010056141.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033964.1", "url": "https://www.ensembl.org/id/ENSGALP00010033964.1" } ] } }, { "isoform_ac": "A0A8V0ZR46-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSZ2/entry#A0A8V0ZR46-1", "sequence": { "sequence": "MQRTAQRALAQSAIAAAAEERRARSERSAVSPCGVTALCHCHRCVFLPPHPPCCVTAPCPRAAVTPHGPTGRRGGGGGGGARFAGTARAVGGPQRSGAVRCGAGMAGLSLPGLFVPWLCLSALLGGGSLALIRGSHPCRLLVGAPQAPALPSQAANRTGGLFACPLTSEPSDCWRVPIDEGVDLQRESKENQWLGVSVKSQGAGGKIVTCAHRYEARNRVQQPLETRDVIGRCFVLSQDLQVHDELDGGEWKFCEGRPQGHDRFGFCQQGLAAAFSPDQVPPVPFSPILGSAGNMRVELLNQSSLDLLRYDDGPYEAGGEKDQDPSLIPVPANSYFGFSVDSGAGLTRRRELSFVSGAPRANHTGAVVILRRDSAHRLVPEAVLPGEQLTSAFGYALAVLDLNTGWTWWWGAPHFFERKAEIGGAAYVYINPAGHWDAATPLRLTGTHGSMFGIALGTAGDLNLDGFEGEGLGCGRGLWCPHCSQCHGCSRPQVLDGEGVGVRTFGYALSGGVDVDGNLYPDLLVGSLSDAVVLYRARPVVYISRNVSLLPANIDLEQSNCQHQEGICVDVQACFSYTATPASYSPPLGDTAPSLSHHGDGWVTPPRVTFLGRRPSDPEHQISHTVELPRQHARTCTTATFQLQDSIRDKLRPITVTLAYGIQGAGTPRHSRSATLPPLPPVLSPQQPSSHRTEVHFLNNLQLRFQFCTRLGDADFLPLPKGADGTAIFAMSDQKDVALEIHVTNMPSDPTEPQRDGDDAHEAVLTARFPQELPYSAVRPYDGRTAPDKPVVCLANQNGSQVECELGNPMKRGAQVRFYLILSTLGITLQTTDLAVELALSTISEQPTLEPVVARARVVIELPLSVTGVAVPPRLFFGGTVRGESAVRRESHVGSAVLFEVTVSNRGPSLKTLGSAFLTLLWPHELSNGKWLLYPLQLELLAAPGLRTVCSPAANPLRLALEPPGEAEVTEEAAVESWWVPAPAERRRNVTLDCAQGTARCMAFRCPLYSFERAAVLTARGRLWNSTFLEEYLAVTSVELIVRASVSVTSSIKNLVLKDASTQIPVTIYLDPGVAVAGGVPWWVILLAVLAGILVLALLIFILWKLGFFRRARYVPPAVPQYHAVKIPREERQQYREEKMGTIQRKEWAVNWSEPSDGHVTPSSA", "length": 1165, "header": "tr|A0A8V0ZR46-1|A0A8V0ZR46_CHICK Computationally mapped isoform of Integrin subunit alpha 7 OS=Gallus gallus OX=9031 GN=ITGA7 PE=3 SV=1 CANONICAL=A0A8V0ZSZ2-1" }, "locus": { "chromosome": "34", "start_pos": 1834265, "end_pos": 1821137, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056160.1", "url": "https://www.ensembl.org/id/ENSGALT00010056160.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033981.1", "url": "https://www.ensembl.org/id/ENSGALP00010033981.1" } ] } }, { "isoform_ac": "A0A8V0ZSZ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSZ2/entry#A0A8V0ZSZ2-1", "sequence": { "sequence": "MQRTAQRALAQSAIAAAAEERRARSERSAVSPCGVTALCHCHRCVFLPPHPPCCVTAPCPRAAVTPHGPTGRRGGGGGGGARFAGTARAVGGPQRSGAVRCGAGMAGLSLPGLFVPWLCLSALLGGGSLALIRGSHPCRLLVGAPQAPALPSQAANRTGGLFACPLTSEPSDCWRVPIDEGVDLQRESKENQWLGVSVKSQGAGGKIVTCAHRYEARNRVQQPLETRDVIGRCFVLSQDLQVHDELDGGEWKFCEGRPQGHDRFGFCQQGLAAAFSPDQHYVLFGAVPPVPFSPILGSAGNMRVELLNQSSLDLLRYDDGPYEAGGEKDQDPSLIPVPANSYFGLLFVTNIDSSDPDQLVYKSPDPSEKVPGAAGDVPQNSYLGFSVDSGAGLTRRRELSFVSGAPRANHTGAVVILRRDSAHRLVPEAVLPGEQLTSAFGYALAVLDLNTGWTWWWGAPHFFERKAEIGGAAYVYINPAGHWDAATPLRLTGTHGSMFGIALGTAGDLNLDGFEGEGLGCGRGLWCPHCSQCHGCSRPQVLDGEGVGVRTFGYALSGGVDVDGNLYPDLLVGSLSDAVVLYRARPVVYISRNVSLLPANIDLEQSNCQHQEGICVDVQACFSYTATPASYSPPLGDTAPSLSHHGDGWVTPPRVTFLGRRPSDPEHQISHTVELPRQHARTCTTATFQLQDSIRDKLRPITVTLAYGIQGAGTPRHSRSATLPPLPPVLSPQQPSSHRTEVHFLNNLQLRFQFCTRLGDADFLPLPKGADGTAIFAMSDQKDVALEIHVTNMPSDPTEPQRDGDDAHEAVLTARFPQELPYSAVRPYDGRTAPDKPVVCLANQNGSQVECELGNPMKRGAQVRFYLILSTLGITLQTTDLAVELALSTISEQPTLEPVVARARVVIELPLSVTGVAVPPRLFFGGTVRGESAVRRESHVGSAVLFEVTVSNRGPSLKTLGSAFLTLLWPHELSNGKWLLYPLQLELLAAPGLRTVCSPAANPLRLALEPPGEAEVTEEAAVESWWVPAPAERRRNVTLDCAQGTARCMAFRCPLYSFERAAVLTARGRLWNSTFLEEYLAVTSVELIVRASVSVTSSIKNLVLKDASTQIPVTIYLDPGVAVAGGVPWWVILLAVLAGILVLALLIFILWKLGFFRRARYVPPAVPQYHAVKIPREERQQYREEKMGTIQRKEWAVNWSEPSDGHVTPSSA", "length": 1212, "header": "tr|A0A8V0ZSZ2-1|A0A8V0ZSZ2_CHICK Isoform 1 of Integrin subunit alpha 7 OS=Gallus gallus OX=9031 GN=ITGA7 PE=3 SV=1 CANONICAL=A0A8V0ZSZ2-1" }, "locus": { "chromosome": "34", "start_pos": 1834265, "end_pos": 1821137, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056126.1", "url": "https://www.ensembl.org/id/ENSGALT00010056126.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033953.1", "url": "https://www.ensembl.org/id/ENSGALP00010033953.1" } ] } }, { "isoform_ac": "A0A8V0ZT12-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSZ2/entry#A0A8V0ZT12-1", "sequence": { "sequence": "MQRTAQRALAQSAIAAAAEERRARSERSAVSPCGVTALCHCHRCVFLPPHPPCCVTAPCPRAAVTPHGPTGRRGGGGGGGARFAGTARAVGGPQRSGAVRCGAGMAGLSLPGLFVPWLCLSALLGGGSLALIRGSHPCRLLVGAPQAPALPSQAANRTGGLFACPLTSEPSDCWRVPIDEGVDLQRESKENQWLGVSVKSQGAGGKIVTCAHRYEARNRVQQPLETRDVIGRCFVLSQDLQVHDELDGGEWKFCEGRPQGHDRFGFCQQGLAAAFSPDQHYVLFGAVPPVPFSPILGSAGNMRVELLNQSSLDLLRYDDGPYEAGGEKDQDPSLIPVPANSYFGLLFVTNIDSSDPDQLVYKSPDPSEKVPGAAGDVPQNSYLGFSVDSGAGLTRRRELSFVSGAPRANHTGAVVILRRDSAHRLVPEAVLPGEQLTSAFGYALAVLDLNTGWTWWWGAPHFFERKAEIGGAAYVYINPAGHWDAATPLRLTGTHGSMFGIALGTAGDLNLDGFEGEGLGCGRGLWCPHCSQCHGCSRPQVLDGEGVGVRTFGYALSGGVDVDGNLYPDLLVGSLSDAVVLYRARPVVYISRNVSLLPANIDLEQSNCQHQEGICVDVQACFSYTATPASYSPPLGDTAPSLSHHGDGWVTPPRVTFLGRRPSDPEHQISHTVELPRQHARTCTTATFQLQDSIRDKLRPITVTLAYGIQGAGTPRHSRSATLPPLPPVLSPQQPSSHRTEVHFLNNLQLRFQFCTRLGDADFLPLPKGADGTAIFAMSDQKDVALEIHVTNMPSDPTEPQRDGDDAHEAVLTARFPQELPYSAVRPYDGRTAPDKPVVCLANQNGSQVECELGNPMKRGAQVRFYLILSTLGITLQTTDLAVELALSTISEQPTLEPVVARARVVIELPLSVTGVAVPPRLFFGGTVRGESAVRRESHVGSAVLFEVTVSNRGPSLKTLGSAFLTLLWPHELSNGKWLLYPLQLELLAAPGLRTVCSPAANPLRLALEPPGEAEVTEEAAVESWWVPAPAERRRNVTLDCAQGTARCMAFRCPLYSFERAAVLTARGRLWNSTFLEEYLAVTSVELIVRASVSVTSSIKNLVLKDASTQIPVTIYLDPGVAVAGGVPWWVILLAVLAGILVLALLIFILWKCGFFKRSSPTSRYTANYYRARRGLQPSEVDKQALQGQR", "length": 1190, "header": "tr|A0A8V0ZT12-1|A0A8V0ZT12_CHICK Computationally mapped isoform of Integrin subunit alpha 7 OS=Gallus gallus OX=9031 GN=ITGA7 PE=3 SV=1 CANONICAL=A0A8V0ZSZ2-1" }, "locus": { "chromosome": "34", "start_pos": 1833349, "end_pos": 1821137, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056150.1", "url": "https://www.ensembl.org/id/ENSGALT00010056150.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033973.1", "url": "https://www.ensembl.org/id/ENSGALP00010033973.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 627, "start_aa": "Thr", "end_pos": 627, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr627", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 65, "start_aa": "Thr", "end_pos": 65, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr65", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-GGA-3000178", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3000178", "resource": "Reactome", "description": "ECM proteoglycans" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", 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}, { "id": "A0A8V0ZUI8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUI8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZUI8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUI8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMQESGTETKSNGSAIQNGASGGNHLLECSLREVRSNGETPSVEIGAADLTHLQQQQALQVARQLLLQQQQQQQQQQQQQQQQQVSGLKSPKRNDKQPALQVPVSVAMMTPQVITPQQMQQILQQQVLTPQQLQVLLQQQQALMLQQQQLQEFYKKQQEQLQLQLLQQQHAGKQPKEPQQQQVATQQLAFQQQLLQMQQLQQQHLLTLQRQGLLTIQPGQPTLPLQPLAQGMIPTELQQLWKEVTSSHTAEEAASNNHSSLDLSTTCISSSAPSKTSLIINPHASTNGQLSVHTPKRESLSHEEHTHSHPLYGHGVCKWPGCEAVCEDFQSFLKHLNSEHALDDRSTAQCRVQMQVVQQLELQLAKDKERLQAMMTHLHVKSTEPKATPQPLNLVSSVTLSKTVSEASPQSLPHTPTTPTAPITPVTQGPSVITTTSMHNVGPIRRRYSDKYNVPISSADIAQNQEFYKNAEVRPPFTYASLIRQAILESPEKQLTLNEIYNWFTRMFAYFRRNAATWKNAVRHNLSLHKCFVRVENVKGAVWTVDEQEFQKRRPQKISGVEDEFGSFWTVDDEEFKRGRHIQRGRPRKYCPDENFGELVAHNPSLIKNIQTSHTYCTPLNAALQASMAENSIPLYTTASMGNPTLGNLANVMREELNGAMEHTNSNGSDSSPGRSPMQAMHPVHVKEEPLDPDENEGPLSLVTTANHSPDFDHDRDYEDEPVNEDIE", "length": 728, "header": "tr|A0A8V0ZUI8-1|A0A8V0ZUI8_CHICK Isoform 1 of Forkhead box P1 OS=Gallus gallus OX=9031 GN=FOXP1 PE=4 SV=1 CANONICAL=A0A8V0ZUI8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZGP6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUI8/entry#A0A8V0ZGP6-1", "sequence": { "sequence": "MMQESGTETKSNGSAIQNGASGGNHLLECSLREVRSNGETPSVEIGAADLTHLQQQQVPVSVAMMTPQVITPQQMQQILQQQVLTPQQLQVLLQQQQALMLQQQLQEFYKKQQEQLQLQLLQQQHAGKQPKEPQQQQVATQQLAFQQQLLQMQQLQQQHLLTLQRQGLLTIQPGQPTLPLQPLAQGMIPTELQQLWKEVTSSHTAEEAASNNHSSLDLSTTCISSSAPSKTSLIINPHASTNGQLSVHTPKRESLSHEEHTHSHPLYGHGVCKWPGCEAVCEDFQSFLKHLNSEHALDDRSTAQCRVQMQVVQQLELQLAKDKERLQAMMTHLHVKSTEPKATPQPLNLVSSVTLSKTVSEASPQSLPHTPTTPTAPITPVTQGPSVITTTSMHNVGPIRRRYSDKYNVPISSADIAQNQEFYKNAEVRPPFTYASLIRQAILESPEKQLTLNEIYNWFTRMFAYFRRNAATWKNAVRHNLSLHKCFVRVENVKGAVWTVDEQEFQKRRPQKISGNPSLIKNIQTSHTYCTPLNAALQASMAENSIPLYTTASMGNPTLGNLANVMREELNGAMEHTNSNGSDSSPGRSPMQAMHPVHVKEEPLDPDENEGPLSLVTTANHSPDFDHDRDYEDEPVNEDIE", "length": 641, "header": "tr|A0A8V0ZGP6-1|A0A8V0ZGP6_CHICK Computationally mapped isoform of Forkhead box P1 OS=Gallus gallus OX=9031 GN=FOXP1 PE=4 SV=1 CANONICAL=A0A8V0ZUI8-1" }, "locus": { "chromosome": "12", "start_pos": 16238945, "end_pos": 16093657, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053941.1", "url": "https://www.ensembl.org/id/ENSGALT00010053941.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032488.1", "url": "https://www.ensembl.org/id/ENSGALP00010032488.1" } ] } }, { "isoform_ac": "A0A8V0ZGQ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUI8/entry#A0A8V0ZGQ4-1", "sequence": { "sequence": "MMQESGTETKSNGSAIQNGASGGNHLLECSLREVRSNGETPSVEIGAADLTHLQQQQVPVSVAMMTPQVITPQQMQQILQQQVLTPQQLQVLLQQQQALMLQQQQLQEFYKKQQEQLQLQLLQQQHAGKQPKEPQQQQVATQQLAFQQQLLQMQQLQQQHLLTLQRQGLLTIQPGQPTLPLQPLAQGMIPTELQQLWKEVTSSHTAEEAASNNHSSLDLSTTCISSSAPSKTSLIINPHASTNGQLSVHTPKRESLSHEEHTHSHPLYGHGVCKWPGCEAVCEDFQSFLKHLNSEHALDDRSTAQCRVQMQVVQQLELQLAKDKERLQAMMTHLHVKSTEPKATPQPLNLVSSVTLSKTVSEASPQSLPHTPTTPTAPITPVTQGPSVITTTSMHNVGPIRRRYSDKYNVPISSADIAQNQEFYKNAEVRPPFTYASLIRQAILESPEKQLTLNEIYNWFTRMFAYFRRNAATWKNAVRHNLSLHKCFVRVENVKGAVWTVDEQEFQKRRPQKISGNPSLIKNIQTSHTYCTPLNAALQASMAENSIPLYTTASMGNPTLGNLANVMREELNGAMEHTNSNGSDSSPGRSPMQAMHPVHVKEEPLDPDENEGPLSLVTTANHSPDFDHDRDYEDEPVNEDIE", "length": 642, "header": "tr|A0A8V0ZGQ4-1|A0A8V0ZUI8_CHICK Computationally mapped isoform of Forkhead box P1 OS=Gallus gallus OX=9031 GN=FOXP1 PE=4 SV=1 CANONICAL=A0A8V0ZUI8-1" }, "locus": { "chromosome": "12", "start_pos": 16238945, "end_pos": 16093657, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053954.1", "url": "https://www.ensembl.org/id/ENSGALT00010053954.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032498.1", "url": "https://www.ensembl.org/id/ENSGALP00010032498.1" } ] } }, { "isoform_ac": "A0A8V0ZM07-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUI8/entry#A0A8V0ZM07-1", "sequence": { "sequence": "MDDRAGSWNTKALQVARQLLLQQQQQQQQQQQQQQQQQVSGLKSPKRNDKQPALQVPVSVAMMTPQVITPQQMQQILQQQVLTPQQLQVLLQQQQALMLQQQLQEFYKKQQEQLQLQLLQQQHAGKQPKEPQQQQVATQQLAFQQQLLQMQQLQQQHLLTLQRQGLLTIQPGQPTLPLQPLAQGMIPTELQQLWKEVTSSHTAEEAASNNHSSLDLSTTCISSSAPSKTSLIINPHASTNGQLSVHTPKRESLSHEEHTHSHPLYGHGVCKWPGCEAVCEDFQSFLKHLNSEHALDDRSTAQCRVQMQVVQQLELQLAKDKERLQAMMTHLHVKSTEPKATPQPLNLVSSVTLSKTVSEASPQSLPHTPTTPTAPITPVTQGPSVITTTSMHNVGPIRRRYSDKYNVPISSADIAQNQEFYKNAEVRPPFTYASLIRQAILESPEKQLTLNEIYNWFTRMFAYFRRNAATWKNAVRHNLSLHKCFVRVENVKGAVWTVDEQEFQKRRPQKISGNPSLIKNIQTSHTYCTPLNAALQASMAENSIPLYTTASMGNPTLGNLANVMREELNGAMEHTNSNGSDSSPGRSPMQAMHPVHVKEEPLDPDENEGPLSLVTTANHSPDFDHDRDYEDEPVNEDIE", "length": 639, "header": "tr|A0A8V0ZM07-1|A0A8V0ZM07_CHICK Computationally mapped isoform of Forkhead box P1 OS=Gallus gallus OX=9031 GN=FOXP1 PE=4 SV=1 CANONICAL=A0A8V0ZUI8-1" }, "locus": { "chromosome": "12", "start_pos": 16225452, "end_pos": 16093657, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053924.1", "url": "https://www.ensembl.org/id/ENSGALT00010053924.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032475.1", "url": "https://www.ensembl.org/id/ENSGALP00010032475.1" } ] } }, { "isoform_ac": "A0A8V0ZM19-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUI8/entry#A0A8V0ZM19-1", "sequence": { "sequence": "MMQESGTETKSNGSAIQNGASGGNHLLECSLREVRSNGETPSVEIGAADLTHLQQQQQQQQQQQQVSGLKSPKRNDKQPALQVPVSVAMMTPQVITPQQMQQILQQQVLTPQQLQVLLQQQQALMLQQQQLQEFYKKQQEQLQLQLLQQQHAGKQPKEPQQQQVATQQLAFQQQLLQMQQLQQQHLLTLQRQGLLTIQPGQPTLPLQPLAQGMIPTELQQLWKEVTSSHTAEEAASNNHSSLDLSTTCISSSAPSKTSLIINPHASTNGQLSVHTPKRESLSHEEHTHSHPLYGHGVCKWPGCEAVCEDFQSFLKHLNSEHALDDRSTAQCRVQMQVVQQLELQLAKDKERLQAMMTHLHVKSTEPKATPQPLNLVSSVTLSKTVSEASPQSLPHTPTTPTAPITPVTQGPSVITTTSMHNVGPIRRRYSDKYNVPISSADIAQNQEFYKNAEVRPPFTYASLIRQAILESPEKQLTLNEIYNWFTRMFAYFRRNAATWKNAVRHNLSLHKCFVRVENVKGAVWTVDEQEFQKRRPQKISGNPSLIKNIQTSHTYCTPLNAALQASMAENSIPLYTTASMGNPTLGNLANVMREELNGAMEHTNSNGSDSSPGRSPMQAMHPVHVKEEPLDPDENEGPLSLVTTANHSPDFDHDRDYEDEPVNEDIE", "length": 667, "header": "tr|A0A8V0ZM19-1|A0A8V0ZUI8_CHICK Computationally mapped isoform of Forkhead box P1 OS=Gallus gallus OX=9031 GN=FOXP1 PE=4 SV=1 CANONICAL=A0A8V0ZUI8-1" }, "locus": { "chromosome": "12", "start_pos": 16238945, "end_pos": 16093657, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053937.1", "url": "https://www.ensembl.org/id/ENSGALT00010053937.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032485.1", "url": "https://www.ensembl.org/id/ENSGALP00010032485.1" } ] } }, { "isoform_ac": "A0A8V0ZM24-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUI8/entry#A0A8V0ZM24-1", "sequence": { "sequence": "MMQESGTETKSNGSAIQNGASGGNHLLECSLREVRSNGETPSVEIGAADLTHLQQQQALQVARQLLLQQQQQQQQQQQQQQQQQVSGLKSPKRNDKQPALQVPVSVAMMTPQVITPQQMQQILQQQVLTPQQLQVLLQQQQALMLQQQLQEFYKKQQEQLQLQLLQQQHAGKQPKEPQQQQVATQQLAFQQQLLQMQQLQQQHLLTLQRQGLLTIQPGQPTLPLQPLAQGMIPTELQQLWKEVTSSHTAEEAASNNHSSLDLSTTCISSSAPSKTSLIINPHASTNGQLSVHTPKRESLSHEEHTHSHPLYGHGVCKWPGCEAVCEDFQSFLKHLNSEHALDDRSTAQCRVQMQVVQQLELQLAKDKERLQAMMTHLHVKSTEPKATPQPLNLVSSVTLSKTVSEASPQSLPHTPTTPTAPITPVTQGPSVITTTSMHNVGPIRRRYSDKYNVPISSDIAQNQEFYKNAEVRPPFTYASLIRQAILESPEKQLTLNEIYNWFTRMFAYFRRNAATWKNAVRHNLSLHKCFVRVENVKGAVWTVDEQEFQKRRPQKISGNPSLIKNIQTSHTYCTPLNAALQASMAENSIPLYTTASMGNPTLGNLANVMREELNGAMEHTNSNGSDSSPGRSPMQAMHPVHVKEEPLDPDENEGPLSLVTTANHSPDFDHDRDYEDEPVNEDIE", "length": 684, "header": "tr|A0A8V0ZM24-1|A0A8V0ZUI8_CHICK Computationally mapped isoform of Forkhead box P1 OS=Gallus gallus OX=9031 GN=FOXP1 PE=4 SV=1 CANONICAL=A0A8V0ZUI8-1" }, "locus": { "chromosome": "12", "start_pos": 16238945, "end_pos": 16093657, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053944.1", "url": "https://www.ensembl.org/id/ENSGALT00010053944.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032490.1", "url": "https://www.ensembl.org/id/ENSGALP00010032490.1" } ] } }, { "isoform_ac": "A0A8V0ZNW2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUI8/entry#A0A8V0ZNW2-1", "sequence": { "sequence": "MMQESGTETKSNGSAIQNGASGGNHLLECSLREVRSNGETPSVEIGAADLTHLQQQQALQVARQLLLQQQQQQQQQQQQQQQQQVSGLKSPKRNDKQPALQVPVSVAMMTPQVITPQQMQQILQQQVLTPQQLQVLLQQQQALMLQQQQLQEFYKKQQEQLQLQLLQQQHAGKQPKEPQQQQVATQQLAFQQQLLQMQQLQQQHLLTLQRQGLLTIQPGQPTLPLQPLAQGMIPTELQQLWKEVTSSHTAEEAASNNHSSLDLSTTCISSSAPSKTSLIINPHASTNGQLSVHTPKRESLSHEEHTHSHPLYGHGVCKWPGCEAVCEDFQSFLKHLNSEHALDDRSTAQCRVQMQVVQQLELQLAKDKERLQAMMTHLHVKSTEPKATPQPLNLVSSVTLSKTVSEASPQSLPHTPTTPTAPITPVTQGPSVITTTSMHNVGPIRRRYSDKYNVPISSADIAQNQEFYKNAEVRPPFTYASLIRQAILESPEKQLTLNEIYNWFTRMFAYFRRNAATWKNAVRHNLSLHKCFVRVENVKGAVWTVDEQEFQKRRPQKISGNPSLIKNIQTSHTYCTPLNAALQASMAENSIPLYTTASMGNPTLGNLANVMREELNGAMEHTNSNGSDSSPGRSPMQAMHPVHVKEEPLDPDENEGPLSLVTTANHSPDFDHDRDYEDEPVNEDIE", "length": 686, "header": "tr|A0A8V0ZNW2-1|A0A8V0ZUI8_CHICK Computationally mapped isoform of Forkhead box P1 OS=Gallus gallus OX=9031 GN=FOXP1 PE=4 SV=1 CANONICAL=A0A8V0ZUI8-1" }, "locus": { "chromosome": "12", "start_pos": 16238945, "end_pos": 16093657, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053960.1", "url": "https://www.ensembl.org/id/ENSGALT00010053960.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032502.1", "url": "https://www.ensembl.org/id/ENSGALP00010032502.1" } ] } }, { "isoform_ac": "A0A8V0ZP97-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUI8/entry#A0A8V0ZP97-1", "sequence": { "sequence": "MMQESGTETKSNGSAIQNGASGGNHLLECSLREVRSNGETPSVEIGAADLTHLQQQQVPVSVAMMTPQVITPQQMQQILQQQVLTPQQLQVLLQQQQALMLQQQLQEFYKKQQEQLQLQLLQQQHAGKQPKEPQQQQVATQQLAFQQQLLQMQQLQQQHLLTLQRQGLLTIQPGQPTLPLQPLAQGMIPTELQQLWKEVTSSHTAEEAASNNHSSLDLSTTCISSSAPSKTSLIINPHASTNGQLSVHTPKRESLSHEEHTHSHPLYGHGVCKWPGCEAVCEDFQSFLKHLNSEHALDDRSTAQCRVQMQVVQQLELQLAKDKERLQAMMTHLHVKSTEPKATPQPLNLVSSVTLSKTVSEASPQSLPHTPTTPTAPITPVTQGPSVITTTSMHNVGPIRRRYSDKYNVPISSDIAQNQEFYKNAEVRPPFTYASLIRQAILESPEKQLTLNEIYNWFTRMFAYFRRNAATWKNAVRHNLSLHKCFVRVENVKGAVWTVDEQEFQKRRPQKISGNPSLIKNIQTSHTYCTPLNAALQASMAENSIPLYTTASMGNPTLGNLANVMREELNGAMEHTNSNGSDSSPGRSPMQAMHPVHVKEEPLDPDENEGPLSLVTTANHSPDFDHDRDYEDEPVNEDIE", "length": 640, "header": "tr|A0A8V0ZP97-1|A0A8V0ZP97_CHICK Computationally mapped isoform of Forkhead box P1 OS=Gallus gallus OX=9031 GN=FOXP1 PE=4 SV=1 CANONICAL=A0A8V0ZUI8-1" }, "locus": { "chromosome": "12", "start_pos": 16238945, "end_pos": 16093657, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053951.1", "url": "https://www.ensembl.org/id/ENSGALT00010053951.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032496.1", "url": "https://www.ensembl.org/id/ENSGALP00010032496.1" } ] } }, { "isoform_ac": "A0A8V0ZUI2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUI8/entry#A0A8V0ZUI2-1", "sequence": { "sequence": "MMQESGTETKSNGSAIQNGASGGNHLLECSLREVRSNGETPSVEIGAADLTHLQQQQALQVARQLLLQQQQQQQQQQQQQQQQQVSGLKSPKRNDKQPALQVPVSVAMMTPQVITPQQMQQILQQQVLTPQQLQVLLQQQQALMLQQVIVAFAAPGGWGPQQQQVATQQLAFQQQLLQMQQLQQQHLLTLQRQGLLTIQPGQPTLPLQPLAQGMIPTELQQLWKEVTSSHTAEEAASNNHSSLDLSTTCISSSAPSKTSLIINPHASTNGQLSVHTPKRESLSHEEHTHSHPLYGHGVCKWPGCEAVCEDFQSFLKHLNSEHALDDRSTAQCRVQMQVVQQLELQLAKDKERLQAMMTHLHVKSTEPKATPQPLNLVSSVTLSKTVSEASPQSLPHTPTTPTAPITPVTQGPSVITTTSMHNVGPIRRRYSDKYNVPISSADIAQNQEFYKNAEVRPPFTYASLIRQAILESPEKQLTLNEIYNWFTRMFAYFRRNAATWKNAVRHNLSLHKCFVRVENVKGAVWTVDEQEFQKRRPQKISGNPSLIKNIQTSHTYCTPLNAALQASMAENSIPLYTTASMGNPTLGNLANVMREELNGAMEHTNSNGSDSSPGRSPMQAMHPVHVKEEPLDPDENEGPLSLVTTANHSPDFDHDRDYEDEPVNEDIE", "length": 668, "header": "tr|A0A8V0ZUI2-1|A0A8V0ZUI2_CHICK Computationally mapped isoform of Forkhead box P1 OS=Gallus gallus OX=9031 GN=FOXP1 PE=4 SV=1 CANONICAL=A0A8V0ZUI8-1" }, "locus": { "chromosome": "12", "start_pos": 16238945, "end_pos": 16093657, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053965.1", "url": "https://www.ensembl.org/id/ENSGALT00010053965.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032504.1", "url": "https://www.ensembl.org/id/ENSGALP00010032504.1" } ] } }, { "isoform_ac": "A0A8V0ZUI8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUI8/entry#A0A8V0ZUI8-1", "sequence": { "sequence": "MMQESGTETKSNGSAIQNGASGGNHLLECSLREVRSNGETPSVEIGAADLTHLQQQQALQVARQLLLQQQQQQQQQQQQQQQQQVSGLKSPKRNDKQPALQVPVSVAMMTPQVITPQQMQQILQQQVLTPQQLQVLLQQQQALMLQQQQLQEFYKKQQEQLQLQLLQQQHAGKQPKEPQQQQVATQQLAFQQQLLQMQQLQQQHLLTLQRQGLLTIQPGQPTLPLQPLAQGMIPTELQQLWKEVTSSHTAEEAASNNHSSLDLSTTCISSSAPSKTSLIINPHASTNGQLSVHTPKRESLSHEEHTHSHPLYGHGVCKWPGCEAVCEDFQSFLKHLNSEHALDDRSTAQCRVQMQVVQQLELQLAKDKERLQAMMTHLHVKSTEPKATPQPLNLVSSVTLSKTVSEASPQSLPHTPTTPTAPITPVTQGPSVITTTSMHNVGPIRRRYSDKYNVPISSADIAQNQEFYKNAEVRPPFTYASLIRQAILESPEKQLTLNEIYNWFTRMFAYFRRNAATWKNAVRHNLSLHKCFVRVENVKGAVWTVDEQEFQKRRPQKISGVEDEFGSFWTVDDEEFKRGRHIQRGRPRKYCPDENFGELVAHNPSLIKNIQTSHTYCTPLNAALQASMAENSIPLYTTASMGNPTLGNLANVMREELNGAMEHTNSNGSDSSPGRSPMQAMHPVHVKEEPLDPDENEGPLSLVTTANHSPDFDHDRDYEDEPVNEDIE", "length": 728, "header": "tr|A0A8V0ZUI8-1|A0A8V0ZUI8_CHICK Isoform 1 of Forkhead box P1 OS=Gallus gallus OX=9031 GN=FOXP1 PE=4 SV=1 CANONICAL=A0A8V0ZUI8-1" }, "locus": { "chromosome": "12", "start_pos": 16238945, "end_pos": 16093657, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053972.1", "url": "https://www.ensembl.org/id/ENSGALT00010053972.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032509.1", "url": "https://www.ensembl.org/id/ENSGALP00010032509.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 424, "start_aa": "Thr", "end_pos": 424, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr424", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:416092", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416092", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A9J7GF24-1", "protein_name": "Forkhead box protein P1 isoform X7", "gene_name": "Foxp1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MMQESGSETKSNGSAIQNGSSGGNHLLECGALRDTRSNGEAPAVDLGAADLAHVQQQQQQALQVARQLLLQQQQQQQQQQQQQQQQQQQQQQQQQQVSGLKSPKRNDKQPALQVPVSVAMMTPQVITPQQMQQILQQQVLSPQQLQVLLQQQQALMLQQQQLQEFYKKQQEQLQLQLLQQQHAGKQPKEQQQVATQQLAFQQQLLQMQQLQQQHLLSLQRQGLLTIQPGQPALPLQPLAQGMIPTELQQLWKEVTSAHTAEETTGSNHSSLDLTSTCVSSSAPSKTSLIMNPHASTNGQLSVHTPKRESLSHEEHPHSHPLYGHGVCKWPGCEAVCDDFPAFLKHLNSEHALDDRSTAQCRVQMQVVQQLELQLAKDKERLQAMMTHLHVKSTEPKAAPQPLNLVSSVTLSKSASEASPQSLPHTPTTPTAPLTPVTQGPSVITTTSMHTVGPIRRRYSDKYNVPISSADIAQNQEFYKNAEVRPPFTYASLIRQAILESPEKQLTLNEIYNWFTRMFAYFRRNAATWKGAIRTNLSLHKCFIRVEDEFGSFWTVDDEEFIRGRHIQRGRPRKYCPGENSDELGAHNPSLIKNMQSSHAYCTPLNAALQASMAENSIPLYTTASMGNPTLGNLASAIREELNGAMEHTNSNESDSSPGRSPMQAVHPVHVKEEPLDPEEAEGPLSLVTTANHSPDFDHDRDYEDEPVNEDME", "length": 712 }, "evidence": [ { "id": "A0A8V0ZUI8", "url": "https://omabrowser.org/oma/group/A0A8V0ZUI8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P58462-1", "protein_name": "Forkhead box protein P1", "gene_name": "Foxp1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMQESGSETKSNGSAIQNGSSGGNHLLECGALRDTRSNGEAPAVDLGAADLAHVQQQQQQALQVARQLLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQVSGLKSPKRNDKQPALQVPVSVAMMTPQVITPQQMQQILQQQVLSPQQLQVLLQQQQALMLQQQLQEFYKKQQEQLQLQLLQQQHAGKQPKEQQVATQQLAFQQQLLQMQQLQQQHLLSLQRQGLLTIQPGQPALPLQPLAQGMIPTELQQLWKEVTSAHTAEETTSSNHSSLDLTSTCVSSSAPSKSSLIMNPHASTNGQLSVHTPKRESLSHEEHPHSHPLYGHGVCKWPGCEAVCDDFPAFLKHLNSEHALDDRSTAQCRVQMQVVQQLELQLAKDKERLQAMMTHLHVKSTEPKAAPQPLNLVSSVTLSKSASEASPQSLPHTPTTPTAPLTPVTQGPSVITTTSMHTVGPIRRRYSDKYNVPISSADIAQNQEFYKNAEVRPPFTYASLIRQAILESPEKQLTLNEIYNWFTRMFAYFRRNAATWKNAVRHNLSLHKCFVRVENVKGAVWTVDEVEFQKRRPQKISGNPSLIKNMQSSHAYCTPLNAALQASMAENSIPLYTTASMGNPTLGSLASAIREELNGAMEHTNSNESDSSPGRSPMQAVHPIHVKEEPLDPEEAEGPLSLVTTANHSPDFDHDRDYEDEPVNEDME", "length": 705 }, "evidence": [ { "id": "A0A8V0ZUI8", "url": "https://omabrowser.org/oma/group/A0A8V0ZUI8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q2LE08-1", "protein_name": "Forkhead box protein P1-B", "gene_name": "foxp1b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MMQESGTEAANGTAHQNGAPPSVEGHREVRSKSTTPSSDITASDIINFQQHQALQVARQILLQQQQQSSVHKSPKNNDKQPATQVPVSVAMMTPQVITPQQMQQILQHQVLSPQQLQLLLQQQQALMLQQQLQEFYKKQQEQLHLQLIQQQHGSKQQSKEVSAQQLAFQQQLLQVQQLQQQHLLSLQRQGLLSIQPNQTLPLHTLTQGMIPAELQQLWKEVTNSHVKEENSVTNNGHRGLDLSSPSPVPLKNHNQHGSTNGQYISHSLKREGSTLDDHSPHSHPLYGHGVCKWPGCEAVFEDFQSFLKHLNNEHALDDRSTAQCRVQMQVVQQLELQLAKDKERLQAMMTHLHVKSTEPKPTPQPLNLVSNVALSKTAPAASPPLSLPQTPTTPTAPLTPLSQTHSVITPTSLHSVGPIRRRYSDKYNMPISPDIVQNKEFYMNAEVRPPFTYASLIRQAILESPEKQLTLNEIYNWFTRMFAYFRRNAATWKNAVRHNLSLHKCFVRVENVKGAVWTVDELEFQKRRPQKISGSPALVKNIHTTLGYGPALSAAFQASMAENIPLYTTASIGSPTLNSLASVIREEMNGAMDHGNSNGSDSSPGRSPLPAMHHISVKEEPMDPEEHEGPLSLVTTANHSPDFDHHRDYEDDHGTEDML", "length": 659 }, "evidence": [ { "id": "A0A8V0ZUI8", "url": "https://omabrowser.org/oma/group/A0A8V0ZUI8/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q498D1-1", "protein_name": "Forkhead box protein P1", "gene_name": "Foxp1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MMQESGSEAKSNGSTIQNGSSGGNHLLECGTLRDTRSNGEAPAVDLGAADLAHVQQQQQQALQVARQLLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQVSGLKSPKRNDKQPALQVPVSVAMMTPQVITPQQMQQILQQQVLSPQQLQVLLQQQQALMLQQQQLQEFYKKQQEQLQLQLLQQQHAGKQPKEQQQQQVATQQLAFQQQLLQMQQLQQQHLLSLQRQGLLTIQPGQPALPLQPLAQGMIPTELQQLWKEVTSAHTAEETTGSNHSSLDLTSTCVSSSAPSKTSLIMNPHASTNGQLSVHTPKRESLSHEEHPHSHPLYGHGVCKWPGCEAVCDDFPAFLKHLNSEHALDDRSTAQCRVQMQVVQQLELQLAKDKERLQAMMTHLHVKSTEPKAAPQPLNLVSSVTLSKSASEASPQSLPHTPTTPTAPLTPVTQGPSVITTTSMHTVGPIRRRYSDKYNVPISSADIAQNQEFYKNAEVRPPFTYASLIRQAILESPEKQLTLNEIYNWFTRMFAYFRRNAATWKNAVRHNLSLHKCFVRVENVKGAVWTVDEVEFQKRRPQKISGNPSLIKNMQSGHAYCTPLNAALQASMAENSIPLYTTASMGNPTLGSLASAIREELNGAMEHTNSNESDSSPGRSPMQAVHPIHVKEEPLDPEEAEGPLSLVTTANHSPDFDHDRDYEDEPVNEDME", "length": 711 }, "evidence": [ { "id": "A0A8V0ZUI8", "url": "https://omabrowser.org/oma/group/A0A8V0ZUI8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9H334-1", "protein_name": "Forkhead box protein P1", "gene_name": "FOXP1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MMQESGTETKSNGSAIQNGSGGSNHLLECGGLREGRSNGETPAVDIGAADLAHAQQQQQQALQVARQLLLQQQQQQQVSGLKSPKRNDKQPALQVPVSVAMMTPQVITPQQMQQILQQQVLSPQQLQVLLQQQQALMLQQQQLQEFYKKQQEQLQLQLLQQQHAGKQPKEQQQVATQQLAFQQQLLQMQQLQQQHLLSLQRQGLLTIQPGQPALPLQPLAQGMIPTELQQLWKEVTSAHTAEETTGNNHSSLDLTTTCVSSSAPSKTSLIMNPHASTNGQLSVHTPKRESLSHEEHPHSHPLYGHGVCKWPGCEAVCEDFQSFLKHLNSEHALDDRSTAQCRVQMQVVQQLELQLAKDKERLQAMMTHLHVKSTEPKAAPQPLNLVSSVTLSKSASEASPQSLPHTPTTPTAPLTPVTQGPSVITTTSMHTVGPIRRRYSDKYNVPISSADIAQNQEFYKNAEVRPPFTYASLIRQAILESPEKQLTLNEIYNWFTRMFAYFRRNAATWKNAVRHNLSLHKCFVRVENVKGAVWTVDEVEFQKRRPQKISGNPSLIKNMQSSHAYCTPLNAALQASMAENSIPLYTTASMGNPTLGNLASAIREELNGAMEHTNSNESDSSPGRSPMQAVHPVHVKEEPLDPEEAEGPLSLVTTANHSPDFDHDRDYEDEPVNEDME", "length": 677 }, "evidence": [ { "id": "A0A8V0ZUI8", "url": "https://omabrowser.org/oma/group/A0A8V0ZUI8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 8, "go_terms": [ { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZUI8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUI8" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZUI8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUI8" } ], "pmid": "" }, { "name": "sequence-specific DNA binding", "id": "GO:0043565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043565", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZUI8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUI8" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZUI8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUI8" } ], "pmid": "" }, { "name": "DNA-binding transcription repressor activity, RNA polymerase II-specific", "id": "GO:0001227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001227", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZUI8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUI8" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZUI8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUI8" } ], "pmid": "" }, { "name": "nuclear androgen receptor binding", "id": "GO:0050681", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050681", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZUI8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUI8" } ], "pmid": "" }, { "name": "core promoter sequence-specific DNA binding", "id": "GO:0001046", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001046", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZUI8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUI8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZUI8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUI8" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZUI8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUI8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 23, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZUI8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUI8" } ], "pmid": "" }, { "name": "regulation of interleukin-1 beta production", "id": "GO:0032651", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032651", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZUI8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUI8" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZUI8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUI8" } ], "pmid": "" }, { "name": "negative regulation of gene expression", "id": "GO:0010629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010629", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZUI8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUI8" } ], "pmid": "" }, { "name": "response to lipopolysaccharide", "id": "GO:0032496", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032496", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZUI8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUI8" } ], "pmid": "" }, { "name": "monocyte activation", "id": "GO:0042117", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042117", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZUI8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUI8" } ], "pmid": "" }, { "name": "positive regulation of endothelial cell migration", "id": "GO:0010595", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010595", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZUI8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUI8" } ], "pmid": "" }, { "name": "DNA damage response", "id": "GO:0006974", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006974", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZUI8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUI8" } ], "pmid": "" }, { "name": "regulation of interleukin-12 production", "id": "GO:0032655", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032655", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZUI8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUI8" } ], "pmid": "" }, { "name": "positive regulation of smooth muscle cell proliferation", "id": "GO:0048661", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048661", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZUI8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUI8" } ], "pmid": "" }, { "name": "regulation of inflammatory response", "id": "GO:0050727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050727", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZUI8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUI8" } ], "pmid": "" }, { "name": "osteoclast development", "id": "GO:0036035", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036035", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZUI8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUI8" } ], "pmid": "" }, { "name": "endothelial cell activation", "id": "GO:0042118", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042118", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZUI8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUI8" } ], "pmid": "" }, { "name": "regulation of tumor necrosis factor production", "id": "GO:0032680", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032680", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZUI8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUI8" } ], "pmid": "" }, { "name": "regulation of endothelial tube morphogenesis", "id": "GO:1901509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901509", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZUI8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUI8" } ], "pmid": "" }, { "name": "regulation of chemokine (C-X-C motif) ligand 2 production", "id": "GO:2000341", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000341", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZUI8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUI8" } ], "pmid": "" }, { "name": "negative regulation of B cell apoptotic process", "id": "GO:0002903", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002903", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZUI8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUI8" } ], "pmid": "" }, { "name": "macrophage activation", "id": "GO:0042116", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042116", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZUI8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUI8" } ], "pmid": "" }, { "name": "negative regulation of androgen receptor signaling pathway", "id": "GO:0060766", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060766", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZUI8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUI8" } ], "pmid": "" }, { "name": "positive regulation of B cell receptor signaling pathway", "id": "GO:0050861", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050861", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZUI8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUI8" } ], "pmid": "" }, { "name": "regulation of monocyte differentiation", "id": "GO:0045655", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045655", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZUI8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUI8" } ], "pmid": "" }, { "name": "regulation of defense response to bacterium", "id": "GO:1900424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900424", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZUI8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUI8" } ], "pmid": "" }, { "name": "regulation of macrophage colony-stimulating factor production", "id": "GO:1901256", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901256", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZUI8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUI8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 12, "end_pos": 14, "annotation": "n_glycosylation_sequon" }, { "start_pos": 257, "end_pos": 259, "annotation": "n_glycosylation_sequon" }, { "start_pos": 525, "end_pos": 527, "annotation": "n_glycosylation_sequon" }, { "start_pos": 667, "end_pos": 669, "annotation": "n_glycosylation_sequon" }, { "start_pos": 707, "end_pos": 709, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZUI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUI8" }, { "id": "PS50039", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50039" }, { "id": "PRU00089", "database": "PROSITE", "url": 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"count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZTR8-1", "uniprot_ac": "A0A8V0ZTR8", "uniprot_id": "A0A8V0ZTR8_CHICK", "mass": { "chemical_mass": 78461.0, "monoisotopic_mass": 78461.0 }, "refseq": { "ac": "XP_015134250", "name": "transcription factor 12 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015134250" }, "gene_names": [ { "name": "TCF12", "type": "recommended", "evidence": [ { "id": "A0A8V0ZTR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTR8" } ] }, { "name": "TCF12", "type": "synonym", "evidence": [ { "id": "XP_015134250", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015134250" } ] } ], "protein_names": [ { "name": "Transcription factor 12", "type": "synonym", "evidence": [ { "id": "A0A8V0ZTR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTR8/entry#names_and_taxonomy" } ] }, { "name": "transcription factor 12 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015134250", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015134250" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052541.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On May 17, 2018 this sequence version replaced XP_015134250.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015134250", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015134250" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTR8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTR8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TCF12", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTR8", "locus": { "chromosome": "10", "start_pos": 7424020, "end_pos": 7576643, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010023170", "url": "https://www.ensembl.org/id/ENSGALG00010023170" } ] } } ], "crossref": [ { "id": "A0A8V0ZTR8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZTR8", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd18945", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18945", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "396334", "url": "https://www.ncbi.nlm.nih.gov/gene/396334", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036638", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036638", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051098", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051098", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZRR3", "url": "https://www.orthodb.org/?gene=A0A8V0ZRR3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZRR8", "url": "https://www.orthodb.org/?gene=A0A8V0ZRR8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZRS1", "url": "https://www.orthodb.org/?gene=A0A8V0ZRS1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZTR0", "url": "https://www.orthodb.org/?gene=A0A8V0ZTR0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZTR8", "url": "https://www.orthodb.org/?gene=A0A8V0ZTR8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11793", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11793", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11793:SF11", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11793:SF11", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00010", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00010", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-525793", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-525793", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-8939236", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8939236", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015134250", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015134250", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRR3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRR3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRR3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRR3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRR8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRR8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRR8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRR8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRS1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRS1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRS1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRS1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZTR0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTR0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZTR0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTR0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZTR8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTR8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZTR8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTR8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNAQQQRMAAIGTDKELSDLLDFSAMFSPPVNSGKTRPTTLGSSQFGGSGMDERTGAASWGTSGQPSPSYESSRENGSLHGKSSDLSTDIEKLKPQEGFADSPHYSDHLNDSRLGPHEGLSPTPFMNSNLMGKASDRGPFPLYGRDTGLPGCQTSLLRSDMGLGSPGQLSSSGKPGTTYYPFSGTNQRRRPLHDSPALDPLQTKKVRKVPPGLPSSVYAPSPSSDEFNRESPSYPSPKPPSSMFASTFFMQDGTHNSSDLWSSSNGMSQPGYGGMLGGSSSHMSQSGSYGSLHTHDRLSYPPHSVSPTDINASLPPMSSFHRGSTSSSPYVAASHTPPVNGSENILGNRGNGAGGSQTGDALGKALASIYSPDHTSSSFPSNPSTPVGSPSPLTGASQWSRSGGQAPSSPNYENSLHSLKNRVEQQLHEHLQDAMSFLKDVCEQSRMEDRLDRLDDAIHVLRNHAVGPSTSLSGGHGDIHSLLGPSHNGPIGSLNSSYGASSLVAANRQASMVAAHREESVSLNSNHAVLPSTVSAQSTELNHKTQESYRALSGGLQSQSVAIGPTEIKSEHKEKDENIHEPPSSDDMKSDDESSQKDIKVSSRGRTSSTNEDEDLNPEQKIEREKERRMANNARERLRVRDINEAFKELGRMCQLHLKSEKPQTKLLILHQAVAVILSLEQQVRERNLNPKAACLKRREEEKVSAVSAEPPTPHPGSHPGLSETTNPMGHM", "length": 732, "header": "tr|A0A8V0ZTR8-1|A0A8V0ZTR8_CHICK Isoform 1 of Transcription factor 12 OS=Gallus gallus OX=9031 GN=TCF12 PE=4 SV=1 CANONICAL=A0A8V0ZTR8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZRR3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTR8/entry#A0A8V0ZRR3-1", "sequence": { "sequence": "MQYKAEREVTFPVRHRAQYAVCEVYAPSPSSDEFNRESPSYPSPKPPSSMFASTFFMQDGTHNSSDLWSSSNGMSQPGYGGMLGGSSSHMSQSGSYGSLHTHDRLSYPPHSVSPTDINASLPPMSSFHRGSTSSSPYVAASHTPPVNGSENILGNRGNGAGGSQTGDALGKALASIYSPDHTSSSFPSNPSTPVGSPSPLTGASQWSRSGGQAPSSPNYENSLHSLKNRVEQQLHEHLQDAMSFLKDVCEQSRMEDRLDRLDDAIHVLRNHAVGPSTSLSGGHGDIHSLLGPSHNGPIGSLNSSYGASSLVAANRQASMVAAHREESVSLNSNHAVLPSTVSAQSTELNHKTQESYRALSGGLQSQSVAIGPTEIKSEHKEKDENIHEPPSSDDMKSDDESSQKDIKVSSRGRTSSTNEDEDLNPEQKIEREKERRMANNARERLRVRDINEAFKELGRMCQLHLKSEKPQTKLLILHQAVAVILSLEQQVRERNLNPKAACLKRREEEKVSAVSAEPPTPHPGSHPGLSETTNPMGHM", "length": 539, "header": "tr|A0A8V0ZRR3-1|A0A8V0ZTR8_CHICK Computationally mapped isoform of Transcription factor 12 OS=Gallus gallus OX=9031 GN=TCF12 PE=4 SV=1 CANONICAL=A0A8V0ZTR8-1" }, "locus": { "chromosome": "10", "start_pos": 7463275, "end_pos": 7427712, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056473.1", "url": "https://www.ensembl.org/id/ENSGALT00010056473.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034216.1", "url": "https://www.ensembl.org/id/ENSGALP00010034216.1" } ] } }, { "isoform_ac": "A0A8V0ZRR8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTR8/entry#A0A8V0ZRR8-1", "sequence": { "sequence": "MNAQQQRMAAIGTDKELSDLLDFSAMFSPPVNSGKTRPTTLGSSQFGGSGMDERTGAASWGTSGQPSPSYESSRENGSLHGKSSDLSTDIEKLKPQEGFADSPHYSDHLNDSRLGPHEGLSPTPFMNSNLMGKASDRGPFPLYGRDTGLPGCQTSLLRSDMGLGSPGQLSSSGKPGTTYYPFSGTNQRRRPLHDSPALDPLQTKKVRKVPPGLPSSVYAPSPSSDEFNRESPSYPSPKPPSSMFASTFFMQDGTHNSSDLWSSSNGMSQPGYGGMLGGSSSHMSQSGSYGSLHTHDRLSYPPHSVSPTDINASLPPMSSFHRGSTSSSPYVAASHTPPVNGSENILGNRGNGAGGSQTGDALGKALASIYSPDHTSSSFPSNPSTPVGSPSPLTGASQWSRSGGQAPSSPNYENSLHSLSRMEDRLDRLDDAIHVLRNHAVGPSTSLSGGHGDIHSLLGPSHNGPIGSLNSSYGASSLVAANRQASMVAAHREESVSLNSNHAVLPSTVSAQSTELNHKTQESYRALSGGLQSQSVAIGPTEIKSEHKEKDENIHEPPSSDDMKSDDESSQKDIKVSSRGRTSSTNEDEDLNPEQKIEREKERRMANNARERLRVRDINEAFKELGRMCQLHLKSEKPQTKLLILHQAVAVILSLEQQVRERNLNPKAACLKRREEEKVSAVSAEPPTPHPGSHPGLSETTNPMGHM", "length": 707, "header": "tr|A0A8V0ZRR8-1|A0A8V0ZRR8_CHICK Computationally mapped isoform of Transcription factor 12 OS=Gallus gallus OX=9031 GN=TCF12 PE=4 SV=1 CANONICAL=A0A8V0ZTR8-1" }, "locus": { "chromosome": "10", "start_pos": 7575236, "end_pos": 7427712, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056478.1", "url": "https://www.ensembl.org/id/ENSGALT00010056478.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034221.1", "url": "https://www.ensembl.org/id/ENSGALP00010034221.1" } ] } }, { "isoform_ac": "A0A8V0ZRS1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTR8/entry#A0A8V0ZRS1-1", "sequence": { "sequence": "MNAQQQRMAAIGTDKELSDLLDFSAMFSPPVNSGKTRPTTLGSSQFGGSGMDERTGAASWGTSGQPSPSYESSRENGSLHGKSSDLSTDIEKLKPQEGFADSPHYSDHLNDSRLGPHEGLSPTPFMNSNLMGKASDRGPFPLYGRDTGLPGCQTSLLRSDMGLGSPGQLSSSGKPGTTYYPFSGTNQRRRPLHDSPALDPLQTKKVRKVPPGLPSSVYAPSPSSDEFNRESPSYPSPKPPSSMFASTFFMQDGTHNSSDLWSSSNGMSQPGYGGMLGGSSSHMSQSGSYGSLHTHDRLSYPPHSVSPTDINASLPPMSSFHRGSTSSSPYVAASHTPPVNGSENILGNRGNGAGGSQTGDALGKALASIYSPDHTSSSFPSNPSTPVGSPSPLTGASQWSRSGGQAPSSPNYENSLHSLKNRVEQQLHEHLQDAMSFLKDVCEQSRMEDRLDRLDDAIHVLRNHAVGPSTSLSGGHGDIHSLLGPSHNGPIGSLNSSYGASSLVAANRQASMVAAHREESVSLNSNHAVLPSTVSAQSTELNHKTQESYRALSGGLQSQSVAIGPTEIKSEHKEKDENIHEPPSSDDMKSDDESSQKDIKVSSRGRTSTNEDEDLNPEQKIEREKERRMANNARERLRVRDINEAFKELGRMCQLHLKSEKPQTKLLILHQAVAVILSLEQQVRERNLNPKAACLKRREEEKVSAVSAEPPTPHPGSHPGLSETTNPMGHM", "length": 731, "header": "tr|A0A8V0ZRS1-1|A0A8V0ZRS1_CHICK Computationally mapped isoform of Transcription factor 12 OS=Gallus gallus OX=9031 GN=TCF12 PE=4 SV=1 CANONICAL=A0A8V0ZTR8-1" }, "locus": { "chromosome": "10", "start_pos": 7575236, "end_pos": 7427712, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056483.1", "url": "https://www.ensembl.org/id/ENSGALT00010056483.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034226.1", "url": "https://www.ensembl.org/id/ENSGALP00010034226.1" } ] } }, { "isoform_ac": "A0A8V0ZTR0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTR8/entry#A0A8V0ZTR0-1", "sequence": { "sequence": "MYCAYPVPGVGSSSLMYYYNGKTVYAPSPSSDEFNRESPSYPSPKPPSSMFASTFFMQDGTHNSSDLWSSSNGMSQPGYGGMLGGSSSHMSQSGSYGSLHTHDRLSYPPHSVSPTDINASLPPMSSFHRGSTSSSPYVAASHTPPVNGSENILGNRGNGAGGSQTGDALGKALASIYSPDHTSSSFPSNPSTPVGSPSPLTGASQWSRSGGQAPSSPNYENSLHSLKNRVEQQLHEHLQDAMSFLKDVCEQSRMEDRLDRLDDAIHVLRNHAVGPSTSLSGGHGDIHSLLGPSHNGPIGSLNSSYGASSLVAANRQASMVAAHREESVSLNSNHAVLPSTVSAQSTELNHKTQESYRALSGGLQSQSVAIGPTEIKSEHKEKDENIHEPPSSDDMKSDDESSQKDIKVSSRGRTSSTNEDEDLNPEQKIEREKERRMANNARERLRVRDINEAFKELGRMCQLHLKSEKPQTKLLILHQAVAVILSLEQQVRERNLNPKAACLKRREEEKVSAVSAEPPTPHPGSHPGLSETTNPMGHM", "length": 539, "header": "tr|A0A8V0ZTR0-1|A0A8V0ZTR8_CHICK Computationally mapped isoform of Transcription factor 12 OS=Gallus gallus OX=9031 GN=TCF12 PE=4 SV=1 CANONICAL=A0A8V0ZTR8-1" }, "locus": { "chromosome": "10", "start_pos": 7462731, "end_pos": 7427712, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056470.1", "url": "https://www.ensembl.org/id/ENSGALT00010056470.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034213.1", "url": "https://www.ensembl.org/id/ENSGALP00010034213.1" } ] } }, { "isoform_ac": "A0A8V0ZTR8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTR8/entry#A0A8V0ZTR8-1", "sequence": { "sequence": "MNAQQQRMAAIGTDKELSDLLDFSAMFSPPVNSGKTRPTTLGSSQFGGSGMDERTGAASWGTSGQPSPSYESSRENGSLHGKSSDLSTDIEKLKPQEGFADSPHYSDHLNDSRLGPHEGLSPTPFMNSNLMGKASDRGPFPLYGRDTGLPGCQTSLLRSDMGLGSPGQLSSSGKPGTTYYPFSGTNQRRRPLHDSPALDPLQTKKVRKVPPGLPSSVYAPSPSSDEFNRESPSYPSPKPPSSMFASTFFMQDGTHNSSDLWSSSNGMSQPGYGGMLGGSSSHMSQSGSYGSLHTHDRLSYPPHSVSPTDINASLPPMSSFHRGSTSSSPYVAASHTPPVNGSENILGNRGNGAGGSQTGDALGKALASIYSPDHTSSSFPSNPSTPVGSPSPLTGASQWSRSGGQAPSSPNYENSLHSLKNRVEQQLHEHLQDAMSFLKDVCEQSRMEDRLDRLDDAIHVLRNHAVGPSTSLSGGHGDIHSLLGPSHNGPIGSLNSSYGASSLVAANRQASMVAAHREESVSLNSNHAVLPSTVSAQSTELNHKTQESYRALSGGLQSQSVAIGPTEIKSEHKEKDENIHEPPSSDDMKSDDESSQKDIKVSSRGRTSSTNEDEDLNPEQKIEREKERRMANNARERLRVRDINEAFKELGRMCQLHLKSEKPQTKLLILHQAVAVILSLEQQVRERNLNPKAACLKRREEEKVSAVSAEPPTPHPGSHPGLSETTNPMGHM", "length": 732, "header": "tr|A0A8V0ZTR8-1|A0A8V0ZTR8_CHICK Isoform 1 of Transcription factor 12 OS=Gallus gallus OX=9031 GN=TCF12 PE=4 SV=1 CANONICAL=A0A8V0ZTR8-1" }, "locus": { "chromosome": "10", "start_pos": 7575236, "end_pos": 7427712, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056480.1", "url": "https://www.ensembl.org/id/ENSGALT00010056480.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034223.1", "url": "https://www.ensembl.org/id/ENSGALP00010034223.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 566, "start_aa": "Thr", "end_pos": 566, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr566", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", 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"tr|A0A8V0ZTM1-1|A0A8V0ZTM1_CHICK Isoform 1 of BCL2 like 14 OS=Gallus gallus OX=9031 GN=BCL2L14 PE=1 SV=1 CANONICAL=A0A8V0ZTM1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZTL6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTM1/entry#A0A8V0ZTL6-1", "sequence": { "sequence": "MSSLNDVTMEEILLEDNEQDSIEYRILMAYAQRKLPASKYKKLLKNETKVLKTSSVIRSEDEIQPQGDKSGPSQTSELQHDTKKQKSKKHPKQNFLSRYCLPLLCSRGEQLSPTKTYALNTQMEDLSTSDTCTERPQNRSFQEQSEKADVSHIVDKLSKLVTTRSQPSPSDVTFKMLMHTRSLEQDGRDTTDENEGEGNDEEKTIQTIVALLRKSGDQLEEKFKKDRSFYQRFEDMLSYAFFERLTDLFLENVSADSTNETEDQLQCTKVAFTLEVATRLTAVDNHPMNLVMGFGLKYLQEHFSPWIRDRGGWDKALSSLDQEEVE", "length": 326, "header": "tr|A0A8V0ZTL6-1|A0A8V0ZTM1_CHICK Computationally mapped isoform of BCL2 like 14 OS=Gallus gallus OX=9031 GN=BCL2L14 PE=1 SV=1 CANONICAL=A0A8V0ZTM1-1" }, "locus": { "chromosome": "1", "start_pos": 71721656, "end_pos": 71715632, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056419.1", "url": "https://www.ensembl.org/id/ENSGALT00010056419.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034165.1", "url": "https://www.ensembl.org/id/ENSGALP00010034165.1" } ] } }, { "isoform_ac": "A0A8V0ZTM1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTM1/entry#A0A8V0ZTM1-1", "sequence": { "sequence": "MTTCQKEKPSRATYADAHRACQGADALGSKSSTIWPLGFYDCHQKMQRGGGDRTTGTEHYSEQHLASISCFGTEMSSLNDVTMEEILLEDNEQDSIEYRILMAYAQRKLPASKYKKLLKNETKVLKTSSVIRSEDEIQPQGDKSGPSQTSELQHDTKKQKSKKHPKQNFLSRYCLPLLCSRGEQLSPTKTYALNTQMEDLSTSDTCTERPQNRSFQEQSEKADVSHIVDKLSKLVTTRSQPSPSDVTFKMLMHTRSLEQDGRDTTDENEGEGNDEEKTIQTIVALLRKSGDQLEEKFKKDRSFYQRFEDMLSYAFFERLTDLFLENVSADSTNETEDQLQCTKVAFTLEVATRLTAVDNHPMNLVMGFGLKYLQEHFSPWIRDRGGWDKALSSLDQEEVE", "length": 400, "header": "tr|A0A8V0ZTM1-1|A0A8V0ZTM1_CHICK Isoform 1 of BCL2 like 14 OS=Gallus gallus OX=9031 GN=BCL2L14 PE=1 SV=1 CANONICAL=A0A8V0ZTM1-1" }, "locus": { "chromosome": "1", "start_pos": 71721656, "end_pos": 71692430, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056425.1", "url": "https://www.ensembl.org/id/ENSGALT00010056425.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034170.1", "url": "https://www.ensembl.org/id/ENSGALP00010034170.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:419096", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419096", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTM1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTM1" } ], "pmid": "" }, { "name": "regulation of apoptotic process", "id": "GO:0042981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042981", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTM1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTM1" } ], "pmid": "" }, { "name": "positive regulation of extrinsic apoptotic signaling pathway", "id": "GO:2001238", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2001238", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTM1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTM1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 120, "end_pos": 122, "annotation": "n_glycosylation_sequon" }, { "start_pos": 212, "end_pos": 214, "annotation": "n_glycosylation_sequon" }, { "start_pos": 326, "end_pos": 328, "annotation": "n_glycosylation_sequon" }, { "start_pos": 333, "end_pos": 335, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 120, "end_pos": 122 }, { "start_pos": 212, "end_pos": 214 }, { "start_pos": 326, "end_pos": 328 }, { "start_pos": 333, "end_pos": 335 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZRZ1-1", "uniprot_ac": "A0A8V0ZRZ1", "uniprot_id": "A0A8V0ZRZ1_CHICK", "mass": { "chemical_mass": 85273.0, "monoisotopic_mass": 85273.0 }, "refseq": {}, "gene_names": [ { "name": "COG4", "type": "recommended", "evidence": [ { "id": "A0A8V0ZRZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRZ1" } ] } ], "protein_names": [ { "name": "Conserved oligomeric Golgi complex subunit 4", "type": "recommended", "evidence": [ { "id": "A0A8V0ZRZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRZ1/entry#names_and_taxonomy" } ] }, { "name": "Component of oligomeric Golgi complex 4", "type": "synonym", "evidence": [ { "id": "A0A8V0ZRZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRZ1/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRZ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRZ1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "COG4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRZ1", "locus": { "chromosome": "11", "start_pos": 1786940, "end_pos": 1772285, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010023203", "url": "https://www.ensembl.org/id/ENSGALG00010023203" } ] } } ], "crossref": [ { "id": "A0A8V0ZRZ1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZRZ1", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR013167", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013167", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048682", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048682", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048684", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048684", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZRZ1", "url": "https://www.orthodb.org/?gene=A0A8V0ZRZ1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZU03", "url": "https://www.orthodb.org/?gene=A0A8V0ZU03", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZV21", "url": "https://www.orthodb.org/?gene=A0A8V0ZV21", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24016", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24016", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24016:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24016:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08318", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08318", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF20662", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20662", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF20663", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20663", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-6807878", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6807878", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-6811438", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6811438", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-6811440", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6811440", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZRZ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRZ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRZ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRZ1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZU03", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU03", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZU03-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU03-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZV21", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZV21", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZV21-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZV21-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSVLCSPEGSCASAVVFQSAVQQELDALLEQQGSIESKMVALQRMGPNLQLIEGDAQQLAGMITFTYNLAENVSSKVRQLDLAKNRLYQAIQRADDILDLKFCMDGVQTALRNEDYEQAAAHIHRYLSLDKSVIELSRQGKEGGIIDANLNLLQESEQRLKTIVTEKFDTAMKQGDLPQVERFFKIFPLLGLHEEGLSKFSEYLCKQVAKKAEENLQLVMGTDMSDRRAAVIFADTLTLLFEGIARVVETHQPIVETYYGPGRLYTLIKHLQGECDQQVEKVVEKFVKERDYHRQFQQVQNSMMRSSSAEKIEPRELDPILTEVTLMNARSELYLRFIKRRIVADFEVGDSMASEEVKQEHQKYLDKLLNNCLLSCTMQELIGYYITMEQYFMRETVNKAVAMDSYEKGQLTSSMVDDVFYIVKKCIGRALSSSNIDCLCAMINHSTTELESDFREVLCNKLKQGFPATTFQDFQRGVTSAVNIMHSSLQQGKFDTKGIESTDEAKQSFLVTLNNVEVCSENIMTLKKTLESDCAKLLSQGFGGEQAQAKIDSCLSDMADVSNKFRDLLQEGVNDLNNTAIKPQVKPWINLFLSISHSIEEEEFSDYEANDPWVQQFIVHLEQQMTEFKAGLSPAIYDNLTGLMTSLIATELEKVLLKSSFNRLGGLQFDKELRSLIAYLTTVTTWTIRDKFARLSQIATILNLERVTEILDYWGPNSGPLTWRLTPAEVRRVLALRKDFRDEDIKRLRL", "length": 750, "header": "tr|A0A8V0ZRZ1-1|A0A8V0ZRZ1_CHICK Isoform 1 of Conserved oligomeric Golgi complex subunit 4 OS=Gallus gallus OX=9031 GN=COG4 PE=1 SV=1 CANONICAL=A0A8V0ZRZ1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZRZ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRZ1/entry#A0A8V0ZRZ1-1", "sequence": { "sequence": "MSVLCSPEGSCASAVVFQSAVQQELDALLEQQGSIESKMVALQRMGPNLQLIEGDAQQLAGMITFTYNLAENVSSKVRQLDLAKNRLYQAIQRADDILDLKFCMDGVQTALRNEDYEQAAAHIHRYLSLDKSVIELSRQGKEGGIIDANLNLLQESEQRLKTIVTEKFDTAMKQGDLPQVERFFKIFPLLGLHEEGLSKFSEYLCKQVAKKAEENLQLVMGTDMSDRRAAVIFADTLTLLFEGIARVVETHQPIVETYYGPGRLYTLIKHLQGECDQQVEKVVEKFVKERDYHRQFQQVQNSMMRSSSAEKIEPRELDPILTEVTLMNARSELYLRFIKRRIVADFEVGDSMASEEVKQEHQKYLDKLLNNCLLSCTMQELIGYYITMEQYFMRETVNKAVAMDSYEKGQLTSSMVDDVFYIVKKCIGRALSSSNIDCLCAMINHSTTELESDFREVLCNKLKQGFPATTFQDFQRGVTSAVNIMHSSLQQGKFDTKGIESTDEAKQSFLVTLNNVEVCSENIMTLKKTLESDCAKLLSQGFGGEQAQAKIDSCLSDMADVSNKFRDLLQEGVNDLNNTAIKPQVKPWINLFLSISHSIEEEEFSDYEANDPWVQQFIVHLEQQMTEFKAGLSPAIYDNLTGLMTSLIATELEKVLLKSSFNRLGGLQFDKELRSLIAYLTTVTTWTIRDKFARLSQIATILNLERVTEILDYWGPNSGPLTWRLTPAEVRRVLALRKDFRDEDIKRLRL", "length": 750, "header": "tr|A0A8V0ZRZ1-1|A0A8V0ZRZ1_CHICK Isoform 1 of Conserved oligomeric Golgi complex subunit 4 OS=Gallus gallus OX=9031 GN=COG4 PE=1 SV=1 CANONICAL=A0A8V0ZRZ1-1" }, "locus": { "chromosome": "11", "start_pos": 1786303, "end_pos": 1772644, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056562.1", "url": "https://www.ensembl.org/id/ENSGALT00010056562.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034304.1", "url": "https://www.ensembl.org/id/ENSGALP00010034304.1" } ] } }, { "isoform_ac": "A0A8V0ZU03-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRZ1/entry#A0A8V0ZU03-1", "sequence": { "sequence": "MAAGGDGGVVGCGLSMERVRALTELSELEAAYSRLCEEESAVQQELDALLEQQGSIESKMVALQRMGPNLQLIEGDAQQLAGMITFTYNLAENVSSKVRQLDLAKNRLYQAIQRADDILDLKFCMDGVQTALRNEDYEQAAAHIHRYLSLDKSVIELSRQGKEGGIIDANLNLLQESEQRLKTIVTEKFDTAMKQGDLPQVERFFKIFPLLGLHEEGLSKFSEYLCKQVAKKAEENLQLVMGTDMSDRRAAVIFADTLTLLFEGIARVVETHQPIVETYYGPGRLYTLIKHLQGECDQQVEKVVEKFVKERDYHRQFQQVQNSMMRSSSAEKIEPRELDPILTEVTLMNARSELYLRFIKRRIVADFEVGDSMASEEVKQEHQKYLDKLLNNCLLSCTMQELIGYYITMEQYFMRETVNKAVAMDSYEKGQLTSSMVDDVFYIVKKCIGRALSSSNIDCLCAMINHSTTELESDFREVLCNKLKQGFPATTFQDFQRGVTSAVNIMHSSLQQGKFDTKGIESTDEAKQSFLVTLNNVEVCSENIMTLKKTLESDCAKLLSQGFGGEQAQAKIDSCLSDMADVSNKFRDLLQEGVNDLNNTAIKPQVKPWINLFLSISHSIEEAGLSPAIYDNLTGLMTSLIATELEKVLLKSSFNRLGGLQFDKELRSLIAYLTTVTTWTIRDKFARLSQIATILNLERVTEILDYWGPNSGPLTWRLTPAEVRRVLALRKDFRDEDIKRLRL", "length": 743, "header": "tr|A0A8V0ZU03-1|A0A8V0ZRZ1_CHICK Computationally mapped isoform of Conserved oligomeric Golgi complex subunit 4 OS=Gallus gallus OX=9031 GN=COG4 PE=1 SV=1 CANONICAL=A0A8V0ZRZ1-1" }, "locus": { "chromosome": "11", "start_pos": 1786303, "end_pos": 1772318, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056574.1", "url": "https://www.ensembl.org/id/ENSGALT00010056574.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034316.1", "url": "https://www.ensembl.org/id/ENSGALP00010034316.1" } ] } }, { "isoform_ac": "A0A8V0ZV21-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRZ1/entry#A0A8V0ZV21-1", "sequence": { "sequence": "MAAGGDGGVVGCGLSMERVRALTELSELEAAYSRLCEEESAVQQELDALLEQQGSIESKMVALQRMGPNLQLIEGDAQQLAGMITFTYNLAENVSSKVRQLDLAKNRLYQAIQRADDILDLKFCMDGVQTALRNEDYEQAAAHIHRYLSLDKSVIELSRQGKEGGIIDANLNLLQESEQRLKTIVTEKFDTAMKQGDLPQVERFFKIFPLLGLHEEGLSKFSEYLCKQVAKKAEENLQLVMGTDMSDRRAAVIFADTLTLLFEGIARVVETHQPIVETYYGPGRLYTLIKHLQGECDQQVEKVVEKFVKERDYHRQFQQVQNSMMRSSSAEKIEPRELDPILTEVTLMNARSELYLRFIKRRIVADFEVGDSMASEEVKQEHQKYLDKLLNNCLLSCTMQELIGYYITMEQYFMRETVNKAVAMDSYEKGQLTSSMVDDVFYIVKKCIGRALSSSNIDCLCAMINHSTTELESDFREVLCNKLKQGFPATTFQDFQRGVTSAVNIMHSSLQQGKFDTKGIESTDEAKQSFLVTLNNVEVCSENIMTLKKTLESDCAKLLSQGFGGEQAQAKIDSCLSDMADVSNKFRDLLQEGVNDLNNTAIKPQVKPWINLFLSISHSIEEEEFSDYEANDPWVQQFIVHLEQQMTEFKAGLSPAIYDNLTGLMTSLIATELEKVLLKSSFNRLGGLQFDKELRSLIAYLTTVTTWTIRDKFARLSQIATILNLERLSSFCR", "length": 733, "header": "tr|A0A8V0ZV21-1|A0A8V0ZRZ1_CHICK Computationally mapped isoform of Conserved oligomeric Golgi complex subunit 4 OS=Gallus gallus OX=9031 GN=COG4 PE=1 SV=1 CANONICAL=A0A8V0ZRZ1-1" }, "locus": { "chromosome": "11", "start_pos": 1786172, "end_pos": 1772318, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056568.1", "url": "https://www.ensembl.org/id/ENSGALT00010056568.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034310.1", "url": "https://www.ensembl.org/id/ENSGALP00010034310.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-6807878", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6807878", "resource": "Reactome", "description": "COPI-mediated anterograde transport" }, { "id": "R-GGA-6811438", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6811438", "resource": "Reactome", "description": "Intra-Golgi traffic" }, { "id": "R-GGA-6811440", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6811440", "resource": "Reactome", "description": "Retrograde transport at the Trans-Golgi-Network" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRZ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRZ1" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRZ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRZ1" } ], "pmid": "" }, { "name": "Golgi transport complex", "id": "GO:0017119", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017119", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRZ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRZ1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRZ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRZ1" } ], "pmid": "" }, { "name": "retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum", "id": "GO:0006890", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006890", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRZ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRZ1" } ], "pmid": "" }, { "name": "Golgi organization", "id": "GO:0007030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007030", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRZ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRZ1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 444, "end_pos": 446, "annotation": "n_glycosylation_sequon" }, { "start_pos": 577, "end_pos": 579, "annotation": "n_glycosylation_sequon" }, { "start_pos": 639, "end_pos": 641, "annotation": "n_glycosylation_sequon" }, { "start_pos": 72, "end_pos": 74, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZRZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRZ1" }, { "id": "SM00762", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00762" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "COG4 transport protein middle alpha-helical bundle", "eco_id": "ECO_0000259", "start_pos": 153, "end_pos": 463, "start_aa": "Leu", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 444, "end_pos": 446 }, { "start_pos": 577, "end_pos": 579 }, { "start_pos": 639, "end_pos": 641 }, { "start_pos": 72, "end_pos": 74 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { 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"UniProtKB", "id": "A0A8V0ZSU5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSU5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CCDC15", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSU5", "locus": {} } ], "crossref": [ { "id": "A0A8V0ZSU5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZSU5", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd17344", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17344", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011701", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011701", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020846", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020846", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036259", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036259", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037693", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037693", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044740", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044740", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "AMPYLID", "url": "https://omabrowser.org/oma/group/AMPYLID/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZSU5", "url": "https://www.orthodb.org/?gene=A0A8V0ZSU5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZXY9", "url": "https://www.orthodb.org/?gene=A0A8V0ZXY9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZXZ5", "url": "https://www.orthodb.org/?gene=A0A8V0ZXZ5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A035", "url": "https://www.orthodb.org/?gene=A0A8V1A035", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A060", "url": "https://www.orthodb.org/?gene=A0A8V1A060", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A220", "url": "https://www.orthodb.org/?gene=A0A8V1A220", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A226", "url": "https://www.orthodb.org/?gene=A0A8V1A226", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A5I0", "url": "https://www.orthodb.org/?gene=A0A8V1A5I0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14817", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14817", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14817:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14817:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR43184", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43184", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR43184:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43184:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07690", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07690", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF28517", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF28517", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "71535", "url": "https://www.rhea-db.org/rhea/71535", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZSU5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSU5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZSU5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSU5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZXY9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXY9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZXY9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXY9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZXZ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXZ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZXZ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXZ5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A035", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A035", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A035-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A035-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A060", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A060", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A060-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A060-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A220", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A220", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A220-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A220-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A226", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A226", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A226-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A226-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A5I0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5I0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A5I0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5I0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAMSRGVWGAGCCVPFPWGGLLLLFFGGSHFAKLPPPPTCAPFWLFPGCVPAPVPISSRHGSMGQRERGRLPGAASYGALPTHHTTALSCPGLPAWLRMHARMLRGEQARSRARMLPSSRLRPRAPRGAVGRPARPPRTGRALLGERSLRVAPVGAWVESGPREQSRAFASAFQVEEELKEQQRRKAMRLRHFQGEVKRRVNQQVKMRRKQQLQRSCEAVEKESNLAVQCSGSVLHLTPKKNTCVFRSCPVPAICSSSAHAALAQQQEQGVPSEPFQQQAAQLSKAMRQVRRRLASCRTVPKGTEVPELPGGTWTLGQKQDQSVLYAPVPTEGENEELILAGHHDLPAELQDQMTAPHQAEQDDDFYIKMEFRQFSNGSVKDLSPPESLQRTTLGCQAPLVLWAGIDQEESKKQRQNEYLRCRRLFMSAEREQVKEQQRQKERQKRIAEIKSKKENQRQVEEQRMQEVAKQQEPFLGESVCEILAQLELEERRLKKVKQKEQRNKEYTRYVEALRAEVKEKMKLYNIDLPPLCSCSSDFWESHPTTCANNCIFYKNHKAYSHALQSVISSCDLVDGRPKLPLRHLAALCTCPAKL", "length": 596, "header": "tr|A0A8V0ZSU5-1|A0A8V0ZSU5_CHICK Isoform 1 of Coiled-coil domain containing 15 OS=Gallus gallus OX=9031 GN=CCDC15 PE=4 SV=1 CANONICAL=A0A8V0ZSU5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZSU5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSU5/entry#A0A8V0ZSU5-1", "sequence": { "sequence": "MAAMSRGVWGAGCCVPFPWGGLLLLFFGGSHFAKLPPPPTCAPFWLFPGCVPAPVPISSRHGSMGQRERGRLPGAASYGALPTHHTTALSCPGLPAWLRMHARMLRGEQARSRARMLPSSRLRPRAPRGAVGRPARPPRTGRALLGERSLRVAPVGAWVESGPREQSRAFASAFQVEEELKEQQRRKAMRLRHFQGEVKRRVNQQVKMRRKQQLQRSCEAVEKESNLAVQCSGSVLHLTPKKNTCVFRSCPVPAICSSSAHAALAQQQEQGVPSEPFQQQAAQLSKAMRQVRRRLASCRTVPKGTEVPELPGGTWTLGQKQDQSVLYAPVPTEGENEELILAGHHDLPAELQDQMTAPHQAEQDDDFYIKMEFRQFSNGSVKDLSPPESLQRTTLGCQAPLVLWAGIDQEESKKQRQNEYLRCRRLFMSAEREQVKEQQRQKERQKRIAEIKSKKENQRQVEEQRMQEVAKQQEPFLGESVCEILAQLELEERRLKKVKQKEQRNKEYTRYVEALRAEVKEKMKLYNIDLPPLCSCSSDFWESHPTTCANNCIFYKNHKAYSHALQSVISSCDLVDGRPKLPLRHLAALCTCPAKL", "length": 596, "header": "tr|A0A8V0ZSU5-1|A0A8V0ZSU5_CHICK Isoform 1 of Coiled-coil domain containing 15 OS=Gallus gallus OX=9031 GN=CCDC15 PE=4 SV=1 CANONICAL=A0A8V0ZSU5-1" }, "locus": { "chromosome": "24", "start_pos": 294144, "end_pos": 277796, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010059814.1", "url": "https://www.ensembl.org/id/ENSGALT00010059814.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036574.1", "url": "https://www.ensembl.org/id/ENSGALP00010036574.1" } ] } }, { "isoform_ac": "A0A8V0ZXY9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSU5/entry#A0A8V0ZXY9-1", "sequence": { "sequence": "MRAALAPGVRLLRAVPRDSRYRGLTLVLTFLSYTSYHLSRKPISIVKSQLHLNCSALGTNPHNDSNSTTWCSWAPFDQDNYKELFGALDNAFLVAYAIGMFISGIFGERLPLRYYLSGGMLLSGIFTALFGFGYFLNIHVLWYYIIVQVCNGLAQTTGWPSVVACVGNWFGKGKRGLIMGIWNSHTSVGNILGSLIAGAWVSSEWGLSFIVPGIIIAAVGIVCFFFLVEHPEDVGCNPPLQHDASDEKDPEGVTSEDRSSTDPKEPAEELEAISFLGALRIPGVVEFSLCLLFAKLVSYTFLYWLPLYIVNVGGIFAGLISDYTGGRATTCCVMLVVAAPMLFLYNHVGQNGIGTSIAMLIVCGALVNGPYALITTAVSADLGTHESLKGNARALSTVTAIIDGTGSVGAALGPLLAGLISPTGWNNVFYMLIAADVLACLLLARVVVKEVRAWYGCMARKRGFERF", "length": 467, "header": "tr|A0A8V0ZXY9-1|A0A8V0ZSU5_CHICK Computationally mapped isoform of Coiled-coil domain containing 15 OS=Gallus gallus OX=9031 GN=CCDC15 PE=4 SV=1 CANONICAL=A0A8V0ZSU5-1" }, "locus": { "chromosome": "24", "start_pos": 275523, "end_pos": 268411, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010059795.1", "url": "https://www.ensembl.org/id/ENSGALT00010059795.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036555.1", "url": "https://www.ensembl.org/id/ENSGALP00010036555.1" } ] } }, { "isoform_ac": "A0A8V0ZXZ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSU5/entry#A0A8V0ZXZ5-1", "sequence": { "sequence": "MEGRSCPSATLLLSAPALQSCEEDSGGGAAVSQHQSCTVLMHFAAVCAQLPWTDAGADLPLLHQLPPLPKTHQHRQDQDNYKELFGALDNAFLVAYAIGMFISGIFGERLPLRYYLSGGMLLSGIFTALFGFGYFLNIHVLWYYIIVQVCNGLAQTTGWPSVVACVGNWFGKGKRGLIMGIWNSHTSVGNILGSLIAGAWVSSEWGLSFIVPGIIIAAVGIVCFFFLVEHPEDVGCNPPLQHDASDEKDPEGVTSEDRSSTDPKEPAEELEAISFLGALRIPGVVEFSLCLLFAKLVSYTFLYWLPLYIVNVAHFGAKEAGDLSTLFDVGGILGGIFAGLISDYTGGRATTCCVMLVVAAPMLFLYNHVGQNGIGTSIAMLIVCGALVNGPYALITTAVSADLGTHESLKGNARALSTVTAIIDGTGSVGAALGPLLAGLISPTGWNNVFYMLIAADVLACLLLARVVVKEVRAWYGCMARKRGFERF", "length": 488, "header": "tr|A0A8V0ZXZ5-1|A0A8V0ZSU5_CHICK Computationally mapped isoform of Coiled-coil domain containing 15 OS=Gallus gallus OX=9031 GN=CCDC15 PE=4 SV=1 CANONICAL=A0A8V0ZSU5-1" }, "locus": { "chromosome": "24", "start_pos": 277857, "end_pos": 268411, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010059801.1", "url": "https://www.ensembl.org/id/ENSGALT00010059801.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036560.1", "url": "https://www.ensembl.org/id/ENSGALP00010036560.1" } ] } }, { "isoform_ac": "A0A8V1A035-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSU5/entry#A0A8V1A035-1", "sequence": { "sequence": "MRAALAPGVRLLRAVPRDSRYRGLTLVLTFLSYTSYHLSRKPISIVKVSNTAPHMQPGRIPEDLPGLISSHLFCAPSQSQLHLNCSALGTNPHNDSNSTTWCSWAPFDQDNYKELFGALDNAFLVAYAIGMFISGIFGERLPLRYYLSGGMLLSGIFTALFGFGYFLNIHVLWYYIIVQVCNGLAQTTGWPSVVACVGNWFGKGKRGLIMGIWNSHTSVGNILGSLIAGAWVSSEWGLSFIVPGIIIAAVGIVCFFFLVEHPEDVGCNPPLQHDASDEKDPEGVTSEDRSSTDPKEPAEELEAISFLGALRIPGVVEFSLCLLFAKLVSYTFLYWLPLYIVNVAHFGAKEAGDLSTLFDVGGILGGIFAGLISDYTGGRATTCCVMLVVAAPMLFLYNHVGQNGIGTSIAMLIVCGALVNGPYALITTAVSADLGTHESLKGNARALSTVTAIIDGTGSVGAALGPLLAGLISPTGWNNVFYMLIAADVLACLLLARVVVKEVRAWYGCMARKRGSSVQLTESVLDGK", "length": 528, "header": "tr|A0A8V1A035-1|A0A8V0ZSU5_CHICK Computationally mapped isoform of Coiled-coil domain containing 15 OS=Gallus gallus OX=9031 GN=CCDC15 PE=4 SV=1 CANONICAL=A0A8V0ZSU5-1" }, "locus": { "chromosome": "24", "start_pos": 275523, "end_pos": 269215, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010059782.1", "url": "https://www.ensembl.org/id/ENSGALT00010059782.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036542.1", "url": "https://www.ensembl.org/id/ENSGALP00010036542.1" } ] } }, { "isoform_ac": "A0A8V1A060-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSU5/entry#A0A8V1A060-1", "sequence": { "sequence": "MRSPKGISPLDGRGAVWGLCGAEQARSRARMLPSSRLRPRAPRGAVGRPARPPRTGRALLGERSLRVAPVGAWVESGPREQSRAFASAFQVEEELKEQQRRKAMRLRHFQGEVKRRVNQQVKMRRKQQLQRSCEAVEKESNLAVQCSGSVLHLTPKKNTCVFRSCPVPAICSSSAHAALAQQQEQGVPSEPFQQQAAQLSKAMRQVRRRLASCRTVPKGTEVPELPGGTWTLGQKQDQSVLYAPVPTEGENEELILAGHHDLPAELQDQMTAPHQAEQDDDFYIKMEFRQFSNGSVKDLSPPESLQRTTLGCQAPLVLWAGIDQEESKKQRQNEYLRCRRLFMSAEREQVKEQQRQKERQKRIAEIKSKKENQRQVEEQRMQEVAKQQEPFLGESVCEILAQLELEERRLKKVKQKEQRNKEYTRYVEALRAEVKEKMKLYNIDLPPLCSCSSDFWESHPTTCANNCIFYKNHKAYSHALQSVISSCDLVDGRPKLPLRHLAALCTCPAKL", "length": 511, "header": "tr|A0A8V1A060-1|A0A8V0ZSU5_CHICK Computationally mapped isoform of Coiled-coil domain containing 15 OS=Gallus gallus OX=9031 GN=CCDC15 PE=4 SV=1 CANONICAL=A0A8V0ZSU5-1" }, "locus": { "chromosome": "24", "start_pos": 292875, "end_pos": 277796, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010059807.1", "url": "https://www.ensembl.org/id/ENSGALT00010059807.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036567.1", "url": "https://www.ensembl.org/id/ENSGALP00010036567.1" } ] } }, { "isoform_ac": "A0A8V1A220-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSU5/entry#A0A8V1A220-1", "sequence": { "sequence": "MRAALAPGVRLLRAVPRDSRYRGLTLVLTFLSYTSYHLSRKPISIVKSQLHLNCSALGTNPHNDSNSTTWCSWAPFDQDNYKELFGALDNAFLVAYAIGMFISGIFGERLPLRYYLSGGMLLSGIFTALFGFGYFLNIHVLWYYIIVQVCNGLAQTTGWPSVVACVGNWFGKGKRGLIMGIWNSHTSVGNILGSLIAGAWVSSEWGLSFIVPGIIIAAVGIVCFFFLVEHPEDVGCNPPLQHDASDEKDPEGVTSEDRSSTDPKEPAEELEAISFLGALRIPGVVEFSLCLLFAKLVSYTFLYWLPLYIVNVAHFGAKEAGDLSTLFDVGGILGGIFAGLISDYTGGRATTCCVMLVVAAPMLFLYNHVGQNGIGTSIAMLIVCGALVNGPYALITTAVSADLGTHESLKGNARALSTVTAIIDGTGSVGAALGPLLAGLISPTGWNNVFYMLIAADVLACLLLARVVVKEVRAWYGCMARKRG", "length": 484, "header": "tr|A0A8V1A220-1|A0A8V0ZSU5_CHICK Computationally mapped isoform of Coiled-coil domain containing 15 OS=Gallus gallus OX=9031 GN=CCDC15 PE=4 SV=1 CANONICAL=A0A8V0ZSU5-1" }, "locus": { "chromosome": "24", "start_pos": 275523, "end_pos": 268718, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010059786.1", "url": "https://www.ensembl.org/id/ENSGALT00010059786.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036546.1", "url": "https://www.ensembl.org/id/ENSGALP00010036546.1" } ] } }, { "isoform_ac": "A0A8V1A226-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSU5/entry#A0A8V1A226-1", "sequence": { "sequence": "MRAALAPGVRLLRAVPRDSRYRGLTLVLTFLSYTSYHLSRKPISIVKSQLHLNCSALGTNPHNDSNSTTWCSWAPFDQDNYKELFGALDNAFLVAYAIGMFISGIFGERLPLRYYLSGGMLLSGIFTALFGFGYFLNIHVLWYYIIVQVCNGLAQTTGWPSVVACVGNWFGKGKRGLIMGIWNSHTSVGNILGSLIAGAWVSSEWGLSFIVPGIIIAAVGIVCFFFLVEHPEDVGCNPPLQHDASDEKDPEGVTSEDRSSTDPKEPAEELEAISFLGALRIPGVVEFSLCLLFAKLVSYTFLYWLPLYIVNVAHFGAKEAGDLSTLFDVGGILGGIFAGLISDYTGGRATTCCVMLVVAAPMLFLYNHVGQNGIGTSIAMLIVCGALVNGPYALITTAVSADLGTHESLKGNARALSTVTAIIDGTGSVGAALGPLLAGLISPTGWNNVFYMLIAADVLACLLLARVVVKEVRAWYGCMARKRGYVQRGVGC", "length": 492, "header": "tr|A0A8V1A226-1|A0A8V0ZSU5_CHICK Computationally mapped isoform of Coiled-coil domain containing 15 OS=Gallus gallus OX=9031 GN=CCDC15 PE=4 SV=1 CANONICAL=A0A8V0ZSU5-1" }, "locus": { "chromosome": "24", "start_pos": 275523, "end_pos": 269310, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010059791.1", "url": "https://www.ensembl.org/id/ENSGALT00010059791.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036551.1", "url": "https://www.ensembl.org/id/ENSGALP00010036551.1" } ] } }, { "isoform_ac": "A0A8V1A5I0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSU5/entry#A0A8V1A5I0-1", "sequence": { "sequence": "MRAALAPGVRLLRAVPRDSRYRGLTLVLTFLSYTSYHLSRKPISIVKSQLHLNCSALGTNPHNDSNSTTWCSWAPFDQDNYKELFGALDNAFLVAYAIGMFISGIFGERLPLRYYLSGGMLLSGIFTALFGFGYFLNIHVLWYYIIVQVCNGLAQTTGWPSVVACVGNWFGKGKRGLIMGIWNSHTSVGNILGSLIAGAWVSSEWGLSFIVPGIIIAAVGIVCFFFLVEHPEDVGCNPPLQHDASDEKDPEGVTSEDRSSTDPKEPAEELEAISFLGALRIPGVVEFSLCLLFAKLVSYTFLYWLPLYIVNVAHFGAKEAGDLSTLFDVGGILGGIFAGLISDYTGGRATTCCVMLVVAAPMLFLYNHVGQNGIGTSIAMLIVCGALVNGPYALITTAVSADLGTHESLKGNARALSTVTAIIDGTGSVGAALGPLLAGLISPTGWNNVFYMLIAADVLACLLLARVVVKEVRAWYGCMARKRGGFQHLPSRPVTACVRRSNTSPSAILEGELNYLWQSGQTTESEAPGLV", "length": 531, "header": "tr|A0A8V1A5I0-1|A0A8V0ZSU5_CHICK Computationally mapped isoform of Coiled-coil domain containing 15 OS=Gallus gallus OX=9031 GN=CCDC15 PE=4 SV=1 CANONICAL=A0A8V0ZSU5-1" }, "locus": { "chromosome": "24", "start_pos": 275523, "end_pos": 259033, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010059810.1", "url": "https://www.ensembl.org/id/ENSGALT00010059810.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036570.1", "url": "https://www.ensembl.org/id/ENSGALP00010036570.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 332, "start_aa": "Thr", "end_pos": 332, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr332", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 40, "start_aa": "Thr", "end_pos": 40, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr40", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0ABK0LFP4-1", "protein_name": "Solute carrier family 37 member 2", "gene_name": "Slc37a2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLNFWAPPKHTRRLFQALDLCLFPNNNLTHAPTYFPHLLRLSADILSTKKHSLLFNAHQHPAPPAPASWMKKSMPGGMTPLKKPRNPTKLPLTLNPTKSKDVLAVLAERNQAIVPVGAWVEPASPNWSGIPAHTSAYILEEEIKEQQRRKQESLRHFQRQVKHRVNQQAKLRKKQQLDKSYKAAEKEGSIAIRYSDSAHLTSKRTSVFPRNLNAAVGSFRLPTSLVLGNATDDAENQNQLFEQQAQALSQTMKQARHQLASFKTVSEKKTSVFLNGGKKSSPTQEDLGCGKISSVVVSEERDNLFESCQQDLLSEDKEKALSKVQKVKFKNPLSVVIKEDEGKQLYPHSLQPVLPEAQGYFVEVKSCLPESQSDVIDVQAVEPKASRIEPKEPGGEPDTQAAGMEFQTTEPDGQAVKTEIQDTLKVQTVELDGDTELEAQDSLPSHQAFLSRDQDFLLNCQYQGSLPKDHCVLPNYQNVLPKYQDQHFLPVAQEFLPTNQLALPKEQNHPLKCQKQDLPPEDQFPLPRHQYILPIYQDRRDPHVLPKCQDHDVLSKAQNYLHSYQEQDLPLQSQSQQPSVRTAERWQEDLYLSGHECLPPRQRRDTCSRRQQLCEEYRSGPSTEQQALLPFQSGVDQEEDKKERQKQYLRHRRIFMDIEREQVKEQNRQREQKRRAEKIKKRKEQERYAEEQRLLRVNCPEEPCSEENISDVLAQLQLQEIKGAREKQQQREKEYVRYVEALRAQVQEKMKLYNITLPPLCCCGPDFWDAHPDTCANNCIFYKNYRAYNRALHSVINSSDISEGNATLRNAIRNFASAHRRNFKTKSPVRG", "length": 831 }, "evidence": [ { "id": "A0A8V0ZSU5", "url": "https://omabrowser.org/oma/group/A0A8V0ZSU5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q58CV5-1", "protein_name": "Glucose-6-phosphate exchanger SLC37A2", "gene_name": "SLC37A2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRSSLAPGIWYRAFILLITFLIYTCYHMSRKPISVVKSRLHHNCSEVIQPVNSTHSLNDTTWCNWAPFDKSNYKELLGAVDNAFLVAYAIGMFISGIFGERLPLRYYLTAGMLLSGLFTSLFGLGYFWNIHVLWYFVLVQIFNGLVQTTGWPAVVSCVGNWFGKGKRGLIMGIWNSHTSVGNILGSLLAGVWVDQQWGLSFVVPGVITAIMGIITFFFLIEYPEDVDCSPPQHHGNPEESQDQPEDPANGPSCNKESSLESAVTCSKEASAQPSAISFFGALRIPGVVEFSLCLLFAKLVSYTFLYWLPLYISNVVHFTAKEAGDLSTLFDVGGIIGGILAGLVSDYINGRATTCCVMLILAAPMMFLYNHVGQRGIGISIVMLLICGALVNGPYALITTAVSADLGTHKSLKGNAKALSTVTAIIDGTGSIGAALGPLLAGLISPTGWNNVFYMLIAADVLACLLLCRLVYKEILAWKSSLSKDRGYREM", "length": 491 }, "evidence": [ { "id": "A0A8V0ZSU5", "url": "https://omabrowser.org/oma/group/A0A8V0ZSU5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8MLW5-1", "protein_name": "Major facilitator superfamily transporter 16, isoform B", "gene_name": "MFS16", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MRTSEQKSSWHYSQPKRIREPSHLDEQHLHLAHCPRRSMRASLGLGRTRKMSNNYNDVPFGIRAVQRLSRQCCTRFHARRDLLYKMSVFVLTFLAYACYHMCRKPISVVKSVLQGNCSTALAASGQDCGYAPFDVPDATTLFGMLDSAFLFSYAIAMFASGFVAERVSLRYFLSMGMILTGVFTYMFGIARTSNIHSLWYFIIVQIFAGIFQTTGWPGVVALVGRWFGKSKRGLIFGIWNSHTSIGNILGTLIAAHYVESDWALSFVVPGIIIAAVGFLLFLFLVDQPEIVGCYPQAGQHERRVANESDVEQDDEEQVRHNDAEINYRSAPTERTPILPRSQPEAVPRGRGRPISLIDALFIPGVVEFSLCLFFTKLVSYTFMYWLPLYIQKSSTLGPELSADLSTLFDVGGILGAIAAGYLSDVSGMSATVCTGMLFVASPILLMYQQYGALSMTISIVLLIVVGIFVNGPYALITTSVSAELGQHSSLEGNANALATVTAIIDGTGSIGAAVGPLLAGLISTAGWQYVFHMLIAADIIAMVLLGRLVFKEFAALRRASHRIRIE", "length": 566 }, "evidence": [ { "id": "A0A8V0ZSU5", "url": "https://omabrowser.org/oma/group/A0A8V0ZSU5/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q8TED4-1", "protein_name": "Glucose-6-phosphate exchanger SLC37A2", "gene_name": "SLC37A2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRSSLAPGVWFFRAFSRDSWFRGLILLLTFLIYACYHMSRKPISIVKSRLHQNCSEQIKPINDTHSLNDTMWCSWAPFDKDNYKELLGGVDNAFLIAYAIGMFISGVFGERLPLRYYLSAGMLLSGLFTSLFGLGYFWNIHELWYFVVIQVCNGLVQTTGWPSVVTCVGNWFGKGKRGFIMGIWNSHTSVGNILGSLIAGIWVNGQWGLSFIVPGIITAVMGVITFLFLIEHPEDVDCAPPQHHGEPAENQDNPEDPGNSPCSIRESGLETVAKCSKGPCEEPAAISFFGALRIPGVVEFSLCLLFAKLVSYTFLYWLPLYIANVAHFSAKEAGDLSTLFDVGGIIGGIVAGLVSDYTNGRATTCCVMLILAAPMMFLYNYIGQDGIASSIVMLIICGGLVNGPYALITTAVSADLGTHKSLKGNAKALSTVTAIIDGTGSIGAALGPLLAGLISPTGWNNVFYMLISADVLACLLLCRLVYKEILAWKVSLSRGSGYKEI", "length": 501 }, "evidence": [ { "id": "A0A8V0ZSU5", "url": "https://omabrowser.org/oma/group/A0A8V0ZSU5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9SL56-1", "protein_name": "Putative glycerol-3-phosphate transporter 5", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MQSRIVGLAPAFSLFPNLNTPHKTFTFHQILVLIITFTAYASFHASRKPPSIVKSVLGPPSLNSSSIDNGWAPFNGTQGTKRLGELDLAFLSSYALGMYFAGHLGDRIDLRYFLVFGMMGSGILTLVFGLGYWMNVHTLGFYMSVQIVCGLFQSIGWPCVVSVVGNWCGKEKRGLIMGLWNSHTSVGNILGSVIASSVLDFGWGWSFVLPGVLVLVSGVVVFMFLVVSPNDLGFEELGKEIEIEMSLGENVEESLRKHEAEGAVLLENVDDSSFAIGFLEAWRLPGVAPYAFCLFFSKLVAYTFLYWLPYYLRHTAVAGVNLSHKTAGILSTVFDVGGVLGGISAGFISDKIKARALTSITFLALSIPALIMYRVYGSVSMFINIVLMFISGLLVNGPYALITTAVAADLGTQDSIKGNGRALATVTAIIDGTGSVGAALGPLLAGYISSRGWNSVFFMLIVSIFFAGLFLVRLAKSEINTMRSGELIASSVP", "length": 493 }, "evidence": [ { "id": "A0A8V0ZSU5", "url": "https://omabrowser.org/oma/group/A0A8V0ZSU5/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9WU81-1", "protein_name": "Glucose-6-phosphate exchanger SLC37A2", "gene_name": "Slc37a2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRSSLAPGVWFLRAFSRDSWFRGFILLLTFLIYACYHMSRKPISIVKSRLHQNCSEMVRPVNDTHDLNDTTWCSWSPFDKDDYKELLGAVDNAFLVAYAIGMFISGIFGERLPLRYYLSAGMVLSGLFTSLFGLGYFWNIHMLWYFVLIQICNGLVQTTGWPSVVTCVGNWFGKGKRGFIMGIWNSHTSVGNILGSLIAGVWVNQHWGLSFIVPGIITAIMGVITFLFLIEYPEDVDCTPPRHHDDPEKEQDNPEDPVNSPYSSRESNVDIAASSSKEQGPEPEAISFLGALRIPGVIEFSLCLLFAKLVSYTFLYWLPLYIFNVAHFSAKEAGDLSTLFDVGGIIGGIMAGLISDYTNSRATTCCIMLILAAPMMFLYNYIGQNGITSSIVMLIICGVLVNGPYALITTAVSADLGTHESLKGNAKALSTVTAIIDGTGSIGAALGPLLAGLISPTGWNNVFYMLISADVLACLLLCRLVYKEILAWKTACGRSSGYKQI", "length": 501 }, "evidence": [ { "id": "A0A8V0ZSU5", "url": "https://omabrowser.org/oma/group/A0A8V0ZSU5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSU5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSU5" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSU5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSU5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "glucose 6-phosphate:phosphate antiporter activity", "id": "GO:0061513", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061513", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSU5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSU5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 378, "end_pos": 380, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "71535", "name": "", "equation": "D-glucose 6-phosphate(in) + phosphate(out) = D-glucose 6-phosphate(out) + phosphate(in)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "71535", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/71535" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 40, 332 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 378, "end_pos": 380 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZTF2-1", "uniprot_ac": "A0A8V0ZTF2", "uniprot_id": "A0A8V0ZTF2_CHICK", "mass": { "chemical_mass": 44917.0, "monoisotopic_mass": 44917.0 }, "refseq": {}, "gene_names": [ { "name": "OPCML", "type": "recommended", "evidence": [ { "id": "A0A8V0ZTF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTF2" } ] } ], "protein_names": [ { "name": "Opioid binding protein/cell adhesion molecule like", "type": "synonym", "evidence": [ { "id": "A0A8V0ZTF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTF2/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTF2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTF2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "OPCML", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTF2", "locus": { "chromosome": "24", "start_pos": 2168164, "end_pos": 2423188, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022932", "url": "https://www.ensembl.org/id/ENSGALG00010022932" } ] } } ], "crossref": [ { "id": "A0A8V0ZTF2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZTF2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000001442", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000001442", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "395422", "url": "https://www.ncbi.nlm.nih.gov/gene/395422", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013098", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013098", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013106", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013106", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050876", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050876", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:395422", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395422", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RKYKVGW", "url": "https://omabrowser.org/oma/group/RKYKVGW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1L1RMQ1", "url": "https://www.orthodb.org/?gene=A0A1L1RMQ1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZTF2", "url": "https://www.orthodb.org/?gene=A0A8V0ZTF2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZY35", "url": "https://www.orthodb.org/?gene=A0A8V0ZY35", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NUK2", "url": "https://www.orthodb.org/?gene=F1NUK2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR42757", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR42757", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR42757:SF17", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR42757:SF17", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07679", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07679", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13927", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13927", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A1L1RMQ1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RMQ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1L1RMQ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RMQ1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZTF2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTF2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZTF2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTF2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZY35", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZY35", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZY35-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZY35-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NUK2", "url": "https://www.uniprot.org/uniprotkb/F1NUK2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NUK2-1", "url": "https://www.uniprot.org/uniprotkb/F1NUK2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFPSLPACWLDVSGSFSSSSLGVCRPLSPAVAVYITPGWLEGCADKPNCQQILQLHLQSWASGGCGKPLRRVEVKPNGIFICASPRAVGEKRKGKKAVPFSEESCHDGECRRWWKGCTALVCTVCTVDDRVTRVAWLNRSTILYAGNDKWSIDNRVVILSNTKTQYSIKIHNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIVNISSDITVNEGSSVTLMCLAFGRPEPTVTWRHLSGKGQGFVSEDEYLEITGITREQSGEYECSAVNDVAVPDVRKVKVTVNYPPYISNAKNTGASVGQKGILQCEASAVPVAEFQWFKEDTRLANGLEGVRIESKGRLSTLTFFNVSEKDYGNYTCVATNKLGNTNASIILYGPGAVHDSGNAASRAAAGLCLWATLLARLLLDF", "length": 412, "header": "tr|A0A8V0ZTF2-1|A0A8V0ZTF2_CHICK Isoform 1 of Opioid binding protein/cell adhesion molecule like OS=Gallus gallus OX=9031 GN=OPCML PE=3 SV=1 CANONICAL=A0A8V0ZTF2-1" }, "isoforms": [ { "isoform_ac": "A0A1L1RMQ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTF2/entry#A0A1L1RMQ1-1", "sequence": { "sequence": "MYHPACWIVFTATTALLFIPGVPVRSGDATFPKAMDNVTVRQGESATLRCTVDDRVTRVAWLNRSTILYAGNDKWSIDNRVVILSNTKTQYSIKIHNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIVNISSDITVNEGSSVTLMCLAFGRPEPTVTWRHLSGKGQGFVSEDEYLEITGITREQSGEYECSAVNDVAVPDVRKVKVTVNYPPYISNAKNTGASVGQKGILQCEASAVPVAEFQWFKEDTRLANGLEGVRIESKGRLSTLTFFNVSEKDYGNYTCVATNKLGNTNASIILYGPGAVHDSGNAASRAAAGLCLWATLLARLLLDF", "length": 337, "header": "tr|A0A1L1RMQ1-1|A0A1L1RMQ1_CHICK Computationally mapped isoform of Opioid binding protein/cell adhesion molecule like OS=Gallus gallus OX=9031 GN=OPCML PE=3 SV=1 CANONICAL=A0A8V0ZTF2-1" }, "locus": { "chromosome": "24", "start_pos": 2422332, "end_pos": 2170946, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055838.1", "url": "https://www.ensembl.org/id/ENSGALT00010055838.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033801.1", "url": "https://www.ensembl.org/id/ENSGALP00010033801.1" } ] } }, { "isoform_ac": "A0A8V0ZTF2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTF2/entry#A0A8V0ZTF2-1", "sequence": { "sequence": "MFPSLPACWLDVSGSFSSSSLGVCRPLSPAVAVYITPGWLEGCADKPNCQQILQLHLQSWASGGCGKPLRRVEVKPNGIFICASPRAVGEKRKGKKAVPFSEESCHDGECRRWWKGCTALVCTVCTVDDRVTRVAWLNRSTILYAGNDKWSIDNRVVILSNTKTQYSIKIHNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIVNISSDITVNEGSSVTLMCLAFGRPEPTVTWRHLSGKGQGFVSEDEYLEITGITREQSGEYECSAVNDVAVPDVRKVKVTVNYPPYISNAKNTGASVGQKGILQCEASAVPVAEFQWFKEDTRLANGLEGVRIESKGRLSTLTFFNVSEKDYGNYTCVATNKLGNTNASIILYGPGAVHDSGNAASRAAAGLCLWATLLARLLLDF", "length": 412, "header": "tr|A0A8V0ZTF2-1|A0A8V0ZTF2_CHICK Isoform 1 of Opioid binding protein/cell adhesion molecule like OS=Gallus gallus OX=9031 GN=OPCML PE=3 SV=1 CANONICAL=A0A8V0ZTF2-1" }, "locus": { "chromosome": "24", "start_pos": 2186016, "end_pos": 2170946, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055813.1", "url": "https://www.ensembl.org/id/ENSGALT00010055813.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033791.1", "url": "https://www.ensembl.org/id/ENSGALP00010033791.1" } ] } }, { "isoform_ac": "A0A8V0ZY35-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTF2/entry#A0A8V0ZY35-1", "sequence": { "sequence": "MGVGGCLALPWRCLVVLCLRLLFLVPAGVPVRSGDATFPKAMDNVTVRQGESATLRCTVDDRVTRVAWLNRSTILYAGNDKWSIDNRVVILSNTKTQYSIKIHNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIVNISSDITVNEGSSVTLMCLAFGRPEPTVTWRHLSGKGQGFVSEDEYLEITGITREQSGEYECSAVNDVAVPDVRKVKVTVNYPPYISNAKNTGASVGQKGILQCEASAVPVAEFQWFKEDTRLANGLEGVRIESKGRLSTLTFFNVSEKDYGNYTCVATNKLGNTNASIILYGRYPKCQGNARGQQGEASRAAAGLCLWATLLARLLLDF", "length": 349, "header": "tr|A0A8V0ZY35-1|A0A8V0ZTF2_CHICK Computationally mapped isoform of Opioid binding protein/cell adhesion molecule like OS=Gallus gallus OX=9031 GN=OPCML PE=3 SV=1 CANONICAL=A0A8V0ZTF2-1" }, "locus": { "chromosome": "24", "start_pos": 2256384, "end_pos": 2170946, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055850.1", "url": "https://www.ensembl.org/id/ENSGALT00010055850.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033809.1", "url": "https://www.ensembl.org/id/ENSGALP00010033809.1" } ] } }, { "isoform_ac": "F1NUK2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTF2/entry#F1NUK2-1", "sequence": { "sequence": "MGVGGCLALPWRCLVVLCLRLLFLVPAGVPVRSGDATFPKAMDNVTVRQGESATLRCTVDDRVTRVAWLNRSTILYAGNDKWSIDNRVVILSNTKTQYSIKIHNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIVNISSDITVNEGSSVTLMCLAFGRPEPTVTWRHLSGKGQGFVSEDEYLEITGITREQSGEYECSAVNDVAVPDVRKVKVTVNYPPYISNAKNTGASVGQKGILQCEASAVPVAEFQWFKEDTRLANGLEGVRIESKGRLSTLTFFNVSEKDYGNYTCVATNKLGNTNASIILYGPGAVHDSGNAASRAAAGLCLWATLLARLLLDF", "length": 344, "header": "tr|F1NUK2-1|A0A8V0ZTF2_CHICK Computationally mapped isoform of Opioid binding protein/cell adhesion molecule like OS=Gallus gallus OX=9031 GN=OPCML PE=3 SV=3 CANONICAL=A0A8V0ZTF2-1" }, "locus": { "chromosome": "24", "start_pos": 2256384, "end_pos": 2170946, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055825.1", "url": "https://www.ensembl.org/id/ENSGALT00010055825.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033795.1", "url": "https://www.ensembl.org/id/ENSGALP00010033795.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 36, "start_aa": "Thr", "end_pos": 36, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr36", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:395422", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395422", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A9J7K8Q1-1", "protein_name": "Opioid-binding protein/cell adhesion molecule isoform X1", "gene_name": "Opcml", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MGVCGYLFLPWKCLVVVSLRLLFLVPTGVPVRSGDATFPKAMDNVTVRQGESATLRCTIDDRVTRVAWLNRSTILYAGNDKWSIDPRVIILVNTPTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIGRPEPTVTWRHLSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRKVKITVNYPPYISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEDTRLATGLDGVRIENKGRISTLTFFNVSEKDYGNYTCVATNKLGNTNASITLYEISPSSAVAGPGAVIDGVNSASRALACLWLSGTFFAHFFIKF", "length": 354 }, "evidence": [ { "id": "A0A8V0ZTF2", "url": "https://omabrowser.org/oma/group/A0A8V0ZTF2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G5E8G3-1", "protein_name": "Opioid binding protein/cell adhesion molecule-like", "gene_name": "Opcml", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGVCGYLFLPWKCLVVVSLRLLFLVPTGVPVRSGDATFPKAMDNVTVRQGESATLRCTIDDRVTRVAWLNRSTILYAGNDKWSIDPRVIILVNTPTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIGRPEPTVTWRHLSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRKVKITVNYPPYISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEDTRLATGLDGVRIENKGRISTLTFFNVSEKDYGNYTCVATNKLGNTNASITLYGPGAVIDGVNSASRALACLWLSGTFFAHFFIKF", "length": 345 }, "evidence": [ { "id": "A0A8V0ZTF2", "url": "https://omabrowser.org/oma/group/A0A8V0ZTF2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P11834-1", "protein_name": "Opioid-binding protein/cell adhesion molecule", "gene_name": "OPCML", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGVCGSLFQPWKCLVVVSLRLLFLVPTGVPVRSGDATFPKAMDNVTVRQGESATLRCTIDDRVTRVAWLNRSTILYAGNDKWSIDPRVIILVNTPTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDVTVNEGSSVTLLCLAIGRPEPTVTWRHLSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRKVKITVNYPPYISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEDTRLATGLDGMRIENKGHISTLTFFNVSEKDYGNYTCVATNKLGITNASITLYGPGAVIDGVNSASRALACLWLSGTLFAHFFIKF", "length": 345 }, "evidence": [ { "id": "A0A8V0ZTF2", "url": "https://omabrowser.org/oma/group/A0A8V0ZTF2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P32736-1", "protein_name": "Opioid-binding protein/cell adhesion molecule", "gene_name": "Opcml", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGVCGYLFLPWKCLVVVSLRLLFLVPTGVPVRSGDATFPKAMDNVTVRQGESATLRCTIDDRVTRVAWLNRSTILYAGNDKWSIDPRVIILVNTPTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEISSVTLLCLAIGRPEPTVTWRHLSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRKVKITVNYPPYISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEDTRLATGLDGVRIENKGRISTLTFFNVSEKDYGNYTCVATNKLGNTNASITLYGPGAVIDGVNSASRALACLWLSGTFFAHFFIKF", "length": 345 }, "evidence": [ { "id": "A0A8V0ZTF2", "url": "https://omabrowser.org/oma/group/A0A8V0ZTF2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q14982-1", "protein_name": "Opioid-binding protein/cell adhesion molecule", "gene_name": "OPCML", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGVCGYLFLPWKCLVVVSLRLLFLVPTGVPVRSGDATFPKAMDNVTVRQGESATLRCTIDDRVTRVAWLNRSTILYAGNDKWSIDPRVIILVNTPTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIGRPEPTVTWRHLSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRKVKITVNYPPYISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITLYGPGAVIDGVNSASRALACLWLSGTLLAHFFIKF", "length": 345 }, "evidence": [ { "id": "A0A8V0ZTF2", "url": "https://omabrowser.org/oma/group/A0A8V0ZTF2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTF2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTF2" } ], "pmid": "" }, { "name": "side of membrane", "id": "GO:0098552", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098552", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTF2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTF2" } ], "pmid": "" }, { "name": "cell-cell junction", "id": "GO:0005911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005911", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTF2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTF2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTF2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTF2" } ], "pmid": "" }, { "name": "cell-cell adhesion", "id": "GO:0098609", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098609", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTF2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTF2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "cell adhesion molecule binding", "id": "GO:0050839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050839", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTF2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTF2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 138, "end_pos": 140, "annotation": "n_glycosylation_sequon" }, { "start_pos": 208, "end_pos": 210, "annotation": "n_glycosylation_sequon" }, { "start_pos": 352, "end_pos": 354, "annotation": "n_glycosylation_sequon" }, { "start_pos": 360, "end_pos": 362, "annotation": "n_glycosylation_sequon" }, { "start_pos": 373, "end_pos": 375, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZTF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTF2" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 85, "end_pos": 194, "start_aa": "Pro", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 36 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 138, "end_pos": 140 }, { "start_pos": 208, "end_pos": 210 }, { "start_pos": 352, "end_pos": 354 }, { "start_pos": 360, "end_pos": 362 }, { "start_pos": 373, "end_pos": 375 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZTB0-1", "uniprot_ac": "A0A8V0ZTB0", "uniprot_id": "A0A8V0ZTB0_CHICK", "mass": { "chemical_mass": 33913.0, "monoisotopic_mass": 33913.0 }, "refseq": { "ac": "NP_001026422", "name": "pleckstrin homology domain-containing family A member 3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026422" }, "gene_names": [ { "name": "PLEKHA3", "type": "recommended", "evidence": [ { "id": "A0A8V0ZTB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTB0" } ] }, { "name": "PLEKHA3", "type": "synonym", "evidence": [ { "id": "NP_001026422", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026422" } ] } ], "protein_names": [ { "name": "Pleckstrin homology domain containing A3", "type": "synonym", "evidence": [ { "id": "A0A8V0ZTB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTB0/entry#names_and_taxonomy" } ] }, { "name": "pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 3", "type": "synonym", "evidence": [ { "id": "NP_001026422", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026422" } ] }, { "name": "pleckstrin homology domain-containing family A member 3", "type": "synonym", "evidence": [ { "id": "NP_001026422", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026422" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ719903.1, SRR13267649.302697.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000236.1. On Sep 23, 2021 this sequence version replaced NP_001026422.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001026422", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026422" } ] }, { "annotation": "Plays a role in endocytic trafficking. Required for receptor recycling from endosomes, both to the trans-Golgi network and the plasma membrane.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZVC3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVC3#function" }, { "database": "UniProtKB", "id": "RU369082", "url": "https://www.uniprot.org/uniprotkb/RU369082#function" }, { "database": "UniProtKB", "id": "A0A8V1A0U5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0U5#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTB0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTB0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PLEKHA3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTB0", "locus": { "chromosome": "7", "start_pos": 15008969, "end_pos": 15025363, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010023496", "url": "https://www.ensembl.org/id/ENSGALG00010023496" } ] } } ], "crossref": [ { "id": "A0A8V0ZTB0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZTB0", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd01247", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01247", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "424128", "url": "https://www.ncbi.nlm.nih.gov/gene/424128", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045188", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045188", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:424128", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424128", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VGWQPRW", "url": "https://omabrowser.org/oma/group/VGWQPRW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZTB0", "url": "https://www.orthodb.org/?gene=A0A8V0ZTB0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZVC3", "url": "https://www.orthodb.org/?gene=A0A8V0ZVC3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A0U5", "url": "https://www.orthodb.org/?gene=A0A8V1A0U5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22902", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22902", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22902:SF27", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22902:SF27", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00169", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00169", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001026422", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026422", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZTB0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTB0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZTB0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTB0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZVC3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVC3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZVC3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVC3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A0U5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0U5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A0U5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0U5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEGVLYKWTNYLAGWQPRWFVLDNGILSYYDSQDDVCKGSKGSIKMAVCEIKVHATDNTRMELIIPGEQHFYMKAVNAAERQRWLVALGSAKACLADTRTKKEKEISETNESLKTKMSELRLYCDLLMQQVHTIQEFVHHDETCSPPSIENMNEASSLLSATCNTFITTLEECVKIANAKFKPEMFQLPHPDPLVSPVSPSPVQMMKRSISHPGPCYSERDNHSVKEPVSSLHRLSQQRRRTYSDTESYSDTPLEDSQRSAHCPRNAVNGDLVSSTIPEENRSISNERSELEGSLSSFSS", "length": 300, "header": "tr|A0A8V0ZTB0-1|A0A8V0ZTB0_CHICK Isoform 1 of Pleckstrin homology domain containing A3 OS=Gallus gallus OX=9031 GN=PLEKHA3 PE=4 SV=1 CANONICAL=A0A8V0ZTB0-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZTB0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTB0/entry#A0A8V0ZTB0-1", "sequence": { "sequence": "MEGVLYKWTNYLAGWQPRWFVLDNGILSYYDSQDDVCKGSKGSIKMAVCEIKVHATDNTRMELIIPGEQHFYMKAVNAAERQRWLVALGSAKACLADTRTKKEKEISETNESLKTKMSELRLYCDLLMQQVHTIQEFVHHDETCSPPSIENMNEASSLLSATCNTFITTLEECVKIANAKFKPEMFQLPHPDPLVSPVSPSPVQMMKRSISHPGPCYSERDNHSVKEPVSSLHRLSQQRRRTYSDTESYSDTPLEDSQRSAHCPRNAVNGDLVSSTIPEENRSISNERSELEGSLSSFSS", "length": 300, "header": "tr|A0A8V0ZTB0-1|A0A8V0ZTB0_CHICK Isoform 1 of Pleckstrin homology domain containing A3 OS=Gallus gallus OX=9031 GN=PLEKHA3 PE=4 SV=1 CANONICAL=A0A8V0ZTB0-1" }, "locus": { "chromosome": "7", "start_pos": 15024360, "end_pos": 15010927, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010057241.1", "url": "https://www.ensembl.org/id/ENSGALT00010057241.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034809.1", "url": "https://www.ensembl.org/id/ENSGALP00010034809.1" } ] } }, { "isoform_ac": "A0A8V0ZVC3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTB0/entry#A0A8V0ZVC3-1", "sequence": { "sequence": "MLAAAVSGHQAHCAEARGAGKFLSQTAYFQQSSKRLPQRVIAFPLTPSALGLEGETSLRGGRMPLPPARVPAAQGRPRHVHRRSLAPTCSRTWSRCWPGSRRSARSAGWQPRWFVLDNGILSYYDSQDDVCKGSKGSIKMAVCEIKVHATDNTRMELIIPGEQHFYMKAVNAAERQRWLVALGSAKACLADTRTKKEKEISETNESLKTKMSELRLYCDLLMQQVHTIQEFVHHDETCSPPSIENMNEASSLLSATCNTFITTLEECVKIANAKFKPEMFQLPHPDPLVSPVSPSPVQMMKRSISHPGPCYSERDNHSVKEPVSSLHRLSQQRRRTYSDTESYSDTPLEDSQRSAHCPRNAVNGDLVSSTIPEENRSISNERSELEGSLSSFSS", "length": 394, "header": "tr|A0A8V0ZVC3-1|A0A8V0ZTB0_CHICK Computationally mapped isoform of Pleckstrin homology domain containing A3 OS=Gallus gallus OX=9031 GN=PLEKHA3 PE=4 SV=1 CANONICAL=A0A8V0ZTB0-1" }, "locus": { "chromosome": "7", "start_pos": 15025164, "end_pos": 15010927, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010057245.1", "url": "https://www.ensembl.org/id/ENSGALT00010057245.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034811.1", "url": "https://www.ensembl.org/id/ENSGALP00010034811.1" } ] } }, { "isoform_ac": "A0A8V1A0U5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTB0/entry#A0A8V1A0U5-1", "sequence": { "sequence": "MFLILPGWQPRWFVLDNGILSYYDSQDDVCKGSKGSIKMAVCEIKVHATDNTRMELIIPGEQHFYMKAVNAAERQRWLVALGSAKACLADTRTKKEKEISETNESLKTKMSELRLYCDLLMQQVHTIQEFVHHDETCSPPSIENMNEASSLLSATCNTFITTLEECVKIANAKFKPEMFQLPHPDPLVSPVSPSPVQMIFHTNVTHFIYRDNHSVKEPVSSLHRLSQQRRRTYSDTESYSDTPLEDSQRSAHCPRNAVNGDLVSSTIPEENRSISNERSELEGSLSSFSS", "length": 290, "header": "tr|A0A8V1A0U5-1|A0A8V0ZTB0_CHICK Computationally mapped isoform of Pleckstrin homology domain containing A3 OS=Gallus gallus OX=9031 GN=PLEKHA3 PE=4 SV=1 CANONICAL=A0A8V0ZTB0-1" }, "locus": { "chromosome": "7", "start_pos": 15020712, "end_pos": 15010927, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010057230.1", "url": "https://www.ensembl.org/id/ENSGALT00010057230.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034803.1", "url": "https://www.ensembl.org/id/ENSGALP00010034803.1" } ] } } ], "glycosylation": [], "phosphorylation": 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"MEGVLYKWTNYLTGWQPRWFVLDNGILSYYDSQDDVCKGSKGSIKMAVCEIKVHSADNTRMELIIPGEQHFYMKAVNAAERQRWLVALGSSKACLTDTRTKKEKEISETSESLKTKMSELRLYCDLLMQQVHTIQEFVHHDENHSSPSAENMNEASSLLSATCNTFITTLEECVKIANAKFKPEMFQLHHPDPLVSPVSPSPVQMMKRSVSHPGSCSSERSSHSIKEPVSTLHRLSQRRRRTYSDTDSCSDIPLEDPDRPVHCSKNTLNGDLASATIPEESRLMAKKQSESEDTLPSFSS", "length": 300 }, "evidence": [ { "id": "A0A8V0ZTB0", "url": "https://omabrowser.org/oma/group/A0A8V0ZTB0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTB0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTB0" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTB0", "url": 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZTI6-1", "uniprot_ac": "A0A8V0ZTI6", "uniprot_id": "A0A8V0ZTI6_CHICK", "mass": { "chemical_mass": 110549.0, "monoisotopic_mass": 110549.0 }, "refseq": { "ac": "XP_015130648", "name": "armadillo repeat protein deleted in velo-cardio-facial syndrome isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015130648" }, "gene_names": [ { "name": "ARVCF", "type": "recommended", "evidence": [ { "id": "A0A8V0ZTI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTI6" } ] }, { "name": "ARVCF", "type": "synonym", "evidence": [ { "id": "XP_015130648", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015130648" } ] } ], "protein_names": [ { "name": "Armadillo repeat deleted in velocardiofacial syndrome", "type": "synonym", "evidence": [ { "id": "A0A8V0ZTI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTI6/entry#names_and_taxonomy" } ] }, { "name": "armadillo repeat protein deleted in velo-cardio-facial syndrome isoform X3", "type": "synonym", "evidence": [ { "id": "XP_015130648", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015130648" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052546.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015130648", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015130648" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTI6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTI6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ARVCF", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTI6", "locus": { "chromosome": "15", "start_pos": 1078886, "end_pos": 1267614, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010024616", "url": "https://www.ensembl.org/id/ENSGALG00010024616" } ] } } ], "crossref": [ { "id": "A0A8V0ZTI6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZTI6", "database": 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"http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10372", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10372:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10372:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00514", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00514", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015130648", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015130648", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q2UCR2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UCR2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2UCR2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UCR2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2UN82", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UN82", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2UN82-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UN82-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZTI6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTI6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZTI6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTI6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZYP0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYP0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZYP0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYP0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZYP5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYP5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZYP5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYP5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A0V6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0V6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A0V6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0V6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A671", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A671", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A671-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A671-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDDYDIRSAASILASVKEQEARFERLTRALEEERRNVSLQLERANQPADRMSICNIGNGQPLATAWQQLVLQEQSPSNQTSIAMMQEPQEMVEETVTVEEDPGTPTSHVSIVTSEDGTTRRTETKVTKMVKTVTTRTVRQVPLGPDGLPSMDGSSPMGSYTDSIDRRYMKNGERYITPQASSTLTRSYNSYNDSYPDGHEGQYRPYISHDGYGDLADNYGSLSRGVNYRPRYAYVPGNSYRPDDGSFTLPSRRDNYGPVAQPQVPVGSSVDLNRSQPERFQPEPYGLEDDNRSLGVDDEGYELDPDYSTVNRRTSAGVPERGRPHKGRGYDDPIETEMVEERIPYLHGSYAAPLAQPERGSMASIDRLGKRSPSIDSIRKDPRWRDPDLPEVIAMLSHPIDPVKSNAAAYLQHLCYENDKIKKDVRHLKGIPILVGLLDHPKPEVHRKACGALRNISYGKDNENKVAIKNCDGIPALIRLLRKTNDMEVRELITGTLWNLSSYEPLKMVIINHGLQTLTNEVIIPHSGWESEPNEDSKPRDAEWTTVFKNTSGCLRNVSSDGAEARRRLRECDGLVDALLHALQSAVGKKDTDNKSVENCVCIMRNLSYHVHKEVPGADKYQELDAGQTAGTGGSQKKKKDDAGCFGGKKAKEEWFNQGKKNGDLDRSFDTLDLPKRSETAKGFELLYQPDVVRLYLSILTESQNFNTLEAAAGALQNLSAGNWTWSTYIRATVRKERGLPVLVELLQSDSDKVVRAVSIALRNLSMDRRNKDLIGSYAMGELVRNLPSRQQRSAKNLEEDTVVAVLNTIHEIITDSSENARSLIQTQGIQKLVAISKSSQSPRETKAASHVLQMIWSYKELRNALQKDGWNKSHFQSVSATPKSSKGTAGRSGYDDSTLPLVDKSQDNEKTGSRDMIPMDELGPDGYSTIDHRDKERKYKTSDNTGDASEKEPLKNDTNRKNINRSNRASVNLVDARDIKPQPVDSWV", "length": 989, "header": "tr|A0A8V0ZTI6-1|A0A8V0ZTI6_CHICK Isoform 1 of Armadillo repeat deleted in velocardiofacial syndrome OS=Gallus gallus OX=9031 GN=ARVCF PE=1 SV=1 CANONICAL=A0A8V0ZTI6-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2UCR2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTI6/entry#A0A3Q2UCR2-1", "sequence": { "sequence": "MPAELEQEQSPSNQTSIAMMQEPQEMVEETVTVEEDPGTPTSHVSIVTSEDGTTRRTETKVTKMVKTVTTRTVRQVPLGPDGLPSMDGSSPMGSYTDSIDRRYMKNGERYITPQASSTLTRSYNSYNDSYPDGHEGQYRPYISHDGYGDLADNYGSLSRGVNYRPRYAYVPGNSYRPDDGSFTLPSRRDNYGPVAQPQVPVGSSVDLNRSQPERFQPEPYGLEDDNRSLGVDDEGYELDPDYSTVNRRTSAGVPERGRPHKGRGYDDPIETEMVEERIPYLHGSYAAPLAQPERGSMASIDRLGKRSPSIDSIRKDPRWRDPDLPEVIAMLSHPIDPVKSNAAAYLQHLCYENDKIKKDVRHLKGIPILVGLLDHPKPEVHRKACGALRNISYGKDNENKVAIKNCDGIPALIRLLRKTNDMEVRELITGTLWNLSSYEPLKMVIINHGLQTLTNEVIIPHSGWESEPNEDSKPRDAEWTTVFKNTSGCLRNVSSDGAEARRRLRECDGLVDALLHALQSAVGKKDTDNKSVENCVCIMRNLSYHVHKEVPGADKYQELDAGQTAGTGGSQKKKKDDAGCFGGKKAKGKKNGDLDRSFDTLDLPKRSETAKGFELLYQPDVVRLYLSILTESQNFNTLEAAAGALQNLSAGNWTWSTYIRATVRKERGLPVLVELLQSDSDKVVRAVSIALRNLSMDRRNKDLIGSYAMGELVRNLPSRQQRSAKNLEEDTVVAVLNTIHEIITDSSENARSLIQTQGIQKLVAISKSSQSPRETKAASHVLQMIWSYKELRNALQKDGWNKSHFQSVSATPKSSKGTAGRSGYDDSTLPLVDKSQDNEKTGSRDMIPMDELGPDGYSTIDHRDKERKYKTSDNTGDASEKEPLKNDTNRKNINRSNRASVNLVDARDIKPQPVDSWV", "length": 918, "header": "tr|A0A3Q2UCR2-1|A0A3Q2UCR2_CHICK Computationally mapped isoform of Armadillo repeat deleted in velocardiofacial syndrome OS=Gallus gallus OX=9031 GN=ARVCF PE=1 SV=1 CANONICAL=A0A8V0ZTI6-1" }, "locus": { "chromosome": "15", "start_pos": 1195231, "end_pos": 1082014, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010060073.1", "url": "https://www.ensembl.org/id/ENSGALT00010060073.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036833.1", "url": "https://www.ensembl.org/id/ENSGALP00010036833.1" } ] } }, { "isoform_ac": "A0A3Q2UN82-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTI6/entry#A0A3Q2UN82-1", "sequence": { "sequence": "MISIYEIELSHTSIVAWLVFFETQDSSSSESLFASCWEQSPSNQTSIAMMQEPQEMVEETVTVEEDPGTPTSHVSIVTSEDGTTRRTETKVTKMVKTVTTRTVRQVPLGPDGLPSMDGSSPMGSYTDSIDRRYMKNGERYITPQASSTLTRSYNSYNDSYPDGHEGQYRPYISHDGYGDLADNYGSLSRGVNYRPRYAYVPGNSYRPDDGSFTLPSRRDNYGPVAQPQVPVGSSVDLNRSQPERFQPEPYGLEDDNRSLGVDDEGYELDPDYSTVNRRTSAGVPERGRPHKGRGYDDPIETEMVEERIPYLHGSYAAPLAQPERGSMASIDRLGKRSPSIDSIRKDPRWRDPDLPEVIAMLSHPIDPVKSNAAAYLQHLCYENDKIKKDVRHLKGIPILVGLLDHPKPEVHRKACGALRNISYGKDNENKVAIKNCDGIPALIRLLRKTNDMEVRELITGTLWNLSSYEPLKMVIINHGLQTLTNEVIIPHSGWESEPNEDSKPRDAEWTTVFKNTSGCLRNVSSDGAEARRRLRECDGLVDALLHALQSAVGKKDTDNKSVENCVCIMRNLSYHVHKEVPGADKYQELDAGQTAGTGGSQKKKKDDAGCFGGKKAKGKKNGDLDRSFDTLDLPKRSETAKGFELLYQPDVVRLYLSILTESQNFNTLEAAAGALQNLSAGNWTWSTYIRATVRKERGLPVLVELLQSDSDKVVRAVSIALRNLSMDRRNKDLIGSYAMGELVRNLPSRQQRSAKNLEEDTVVAVLNTIHEIITDSSENARSLIQTQGIQKLVAISKSSQSPRETKAASHVLQMIWSYKELRNALQKDGWNKSHFQSVSATPKSSKGTAGRSGYDDSTLPLVDKSQDNEKTGSRDMIPMDELGPDGYSTIDHRDKERKYKTSDNTGDASEKEPLKG", "length": 916, "header": "tr|A0A3Q2UN82-1|A0A8V0ZTI6_CHICK Computationally mapped isoform of Armadillo repeat deleted in velocardiofacial syndrome OS=Gallus gallus OX=9031 GN=ARVCF PE=1 SV=1 CANONICAL=A0A8V0ZTI6-1" }, "locus": { "chromosome": "15", "start_pos": 1152192, "end_pos": 1080596, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010060067.1", "url": "https://www.ensembl.org/id/ENSGALT00010060067.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036827.1", "url": "https://www.ensembl.org/id/ENSGALP00010036827.1" } ] } }, { "isoform_ac": "A0A8V0ZTI6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTI6/entry#A0A8V0ZTI6-1", "sequence": { "sequence": "MDDYDIRSAASILASVKEQEARFERLTRALEEERRNVSLQLERANQPADRMSICNIGNGQPLATAWQQLVLQEQSPSNQTSIAMMQEPQEMVEETVTVEEDPGTPTSHVSIVTSEDGTTRRTETKVTKMVKTVTTRTVRQVPLGPDGLPSMDGSSPMGSYTDSIDRRYMKNGERYITPQASSTLTRSYNSYNDSYPDGHEGQYRPYISHDGYGDLADNYGSLSRGVNYRPRYAYVPGNSYRPDDGSFTLPSRRDNYGPVAQPQVPVGSSVDLNRSQPERFQPEPYGLEDDNRSLGVDDEGYELDPDYSTVNRRTSAGVPERGRPHKGRGYDDPIETEMVEERIPYLHGSYAAPLAQPERGSMASIDRLGKRSPSIDSIRKDPRWRDPDLPEVIAMLSHPIDPVKSNAAAYLQHLCYENDKIKKDVRHLKGIPILVGLLDHPKPEVHRKACGALRNISYGKDNENKVAIKNCDGIPALIRLLRKTNDMEVRELITGTLWNLSSYEPLKMVIINHGLQTLTNEVIIPHSGWESEPNEDSKPRDAEWTTVFKNTSGCLRNVSSDGAEARRRLRECDGLVDALLHALQSAVGKKDTDNKSVENCVCIMRNLSYHVHKEVPGADKYQELDAGQTAGTGGSQKKKKDDAGCFGGKKAKEEWFNQGKKNGDLDRSFDTLDLPKRSETAKGFELLYQPDVVRLYLSILTESQNFNTLEAAAGALQNLSAGNWTWSTYIRATVRKERGLPVLVELLQSDSDKVVRAVSIALRNLSMDRRNKDLIGSYAMGELVRNLPSRQQRSAKNLEEDTVVAVLNTIHEIITDSSENARSLIQTQGIQKLVAISKSSQSPRETKAASHVLQMIWSYKELRNALQKDGWNKSHFQSVSATPKSSKGTAGRSGYDDSTLPLVDKSQDNEKTGSRDMIPMDELGPDGYSTIDHRDKERKYKTSDNTGDASEKEPLKNDTNRKNINRSNRASVNLVDARDIKPQPVDSWV", "length": 989, "header": "tr|A0A8V0ZTI6-1|A0A8V0ZTI6_CHICK Isoform 1 of Armadillo repeat deleted in velocardiofacial syndrome OS=Gallus gallus OX=9031 GN=ARVCF PE=1 SV=1 CANONICAL=A0A8V0ZTI6-1" }, "locus": { "chromosome": "15", "start_pos": 1204278, "end_pos": 1082014, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010060078.1", "url": "https://www.ensembl.org/id/ENSGALT00010060078.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036838.1", "url": "https://www.ensembl.org/id/ENSGALP00010036838.1" } ] } }, { "isoform_ac": "A0A8V0ZYP0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTI6/entry#A0A8V0ZYP0-1", "sequence": { "sequence": "MPAELEQMKDLACTSDSYVHEQSPSNQTSIAMMQEPQEMVEETVTVEEDPGTPTSHVSIVTSEDGTTRRTETKVTKMVKTVTTRTVRQVPLGPDGLPSMDGSSPMGSYTDSIDRRYMKNGERYITPQASSTLTRSYNSYNDSYPDGHEGQYRPYISHDGYGDLADNYGSLSRGVNYRPRYAYVPGNSYRPDDGSFTLPSRRDNYGPVAQPQVPVGSSVDLNRSQPERFQPEPYGLEDDNRSLGVDDEGYELDPDYSTVNRRTSAGVPERGRPHKGRGYDDPIETEMVEERIPYLHGSYAAPLAQPERGSMASIDRLGKRSPSIDSIRKDPRWRDPDLPEVIAMLSHPIDPVKSNAAAYLQHLCYENDKIKKDVRHLKGIPILVGLLDHPKPEVHRKACGALRNISYGKDNENKVAIKNCDGIPALIRLLRKTNDMEVRELITGTLWNLSSYEPLKMVIINHGLQTLTNEVIIPHSGWESEPNEDSKPRDAEWTTVFKNTSGCLRNVSSDGAEARRRLRECDGLVDALLHALQSAVGKKDTDNKSVENCVCIMRNLSYHVHKEVPGADKYQELDAGQTAGTGGSQKKKKDDAGCFGGKKAKGKKNGDLDRSFDTLDLPKRSETAKGFELLYQPDVVRLYLSILTESQNFNTLEAAAGALQNLSAGNWTWSTYIRATVRKERGLPVLVELLQSDSDKVVRAVSIALRNLSMDRRNKDLIGSYAMGELVRNLPSRQQRSAKNLEEDTVVAVLNTIHEIITDSSENARSLIQTQGIQKLVAISKSSQSPRETKAASHVLQMIWSYKELRNALQKDGWNKSHFQSVSATPKSSKGTAGRSGYDDSTLPLVDKSQDNEKTGSRDMIPMDELGPDGYSTIDHRDKERKYKTSDNTGDASEKEPLKG", "length": 899, "header": "tr|A0A8V0ZYP0-1|A0A8V0ZTI6_CHICK Computationally mapped isoform of Armadillo repeat deleted in velocardiofacial syndrome OS=Gallus gallus OX=9031 GN=ARVCF PE=1 SV=1 CANONICAL=A0A8V0ZTI6-1" }, "locus": { "chromosome": "15", "start_pos": 1195231, "end_pos": 1080596, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010060069.1", "url": "https://www.ensembl.org/id/ENSGALT00010060069.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036829.1", "url": "https://www.ensembl.org/id/ENSGALP00010036829.1" } ] } }, { "isoform_ac": "A0A8V0ZYP5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTI6/entry#A0A8V0ZYP5-1", "sequence": { "sequence": "MGSGRREAAARVARGASFARERGCALRGVAGSGARLGEGRCSRRRASMPAELEQEQSPSNQTSIAMMQEPQEMVEETVTVEEDPGTPTSHVSIVTSEDGTTRRTETKVTKMVKTVTTRTVRQVPLGPDGLPSMDGSSPMGSYTDSIDRRYMKNGERYITPQASSTLTRSYNSYNDSYPDGHEGQYRPYISHDGYGDLADNYGSLSRGVNYRPRYAYVPGNSYRPDDGSFTLPSRRDNYGPVAQPQVPVGSSVDLNRSQPERFQPEPYGLEDDNRSLGVDDEGYELDPDYSTVNRRTSAGVPERGRPHKGRGYDDPIETEMVEERIPYLHGSYAAPLAQPERGSMASIDRLGKRSPSIDSIRKDPRWRDPDLPEVIAMLSHPIDPVKSNAAAYLQHLCYENDKIKKDVRHLKGIPILVGLLDHPKPEVHRKACGALRNISYGKDNENKVAIKNCDGIPALIRLLRKTNDMEVRELITGTLWNLSSYEPLKMVIINHGLQTLTNEVIIPHSGWESEPNEDSKPRDAEWTTVFKNTSGCLRNVSSDGAEARRRLRECDGLVDALLHALQSAVGKKDTDNKSVENCVCIMRNLSYHVHKEVPGADKYQELDAGQTAGTGGSQKKKKDDAGCFGGKKAKGKKNGDLDRSFDTLDLPKRSETAKGFELLYQPDVVRLYLSILTESQNFNTLEAAAGALQNLSAGNWTWSTYIRATVRKERGLPVLVELLQSDSDKVVRAVSIALRNLSMDRRNKDLIGSYAMGELVRNLPSRQQRSAKNLEEDTVVAVLNTIHEIITDSSENARSLIQTQGIQKLVAISKSSQSPRETKAASHVLQMIWSYKELRNALQKDGWNKSHFQSVSATPKSSKGTAGRSGYDDSTLPLVDKSQDNEKTGSRDMIPMDELGPDGYSTIDHRDKERKYKTSDNTGDASEKEPLKG", "length": 933, "header": "tr|A0A8V0ZYP5-1|A0A8V0ZTI6_CHICK Computationally mapped isoform of Armadillo repeat deleted in velocardiofacial syndrome OS=Gallus gallus OX=9031 GN=ARVCF PE=1 SV=1 CANONICAL=A0A8V0ZTI6-1" }, "locus": { "chromosome": "15", "start_pos": 1195397, "end_pos": 1080596, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010060074.1", "url": "https://www.ensembl.org/id/ENSGALT00010060074.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036834.1", "url": "https://www.ensembl.org/id/ENSGALP00010036834.1" } ] } }, { "isoform_ac": "A0A8V1A0V6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTI6/entry#A0A8V1A0V6-1", "sequence": { "sequence": "MDDYDIRSAASILASVKEQEARFERLTRALEEERRNVSLQLERANQPADRMSICNIGNGQPLATAWQQLVLQEQSPSNQTSIAMMQEPQEMVEETVTVEEDPGTPTSHVSIVTSEDGTTRRTETKVTKMVKTVTTRTVRQVPLGPDGLPSMDGSSPMGSYTDSIDRRYMKNGERYITPQASSTLTRSYNSYNDSYPDGHEGQYRPYISHDGYGDLADNYGSLSRGVNYRPRYAYVPGNSYRPDDGSFTLPSRRDNYGPVAQPQVPVGSSVDLNRSQPERFQPEPYGLEDDNRSLGVDDEGYELDPDYSTVNRRTSAGVPERGRPHKGRGYDDPIETEMVEERIPYLHGSYAAPLAQPERGSMASIDRLGKRSPSIDSIRKDPRWRDPDLPEVIAMLSHPIDPVKSNAAAYLQHLCYENDKIKKDVRHLKGIPILVGLLDHPKPEVHRKACGALRNISYGKDNENKVAIKNCDGIPALIRLLRKTNDMEVRELITGTLWNLSSYEPLKMVIINHGLQTLTNEVIIPHSGWESEPNEDSKPRDAEWTTVFKNTSGCLRNVSSDGAEARRRLRECDGLVDALLHALQSAVGKKDTDNKSVENCVCIMRNLSYHVHKEVPGADKYQELDAGQTAGTGGSQKKKKDDAGCFGGKKAKEEWFNQGKKNGDLDRSFDTLDLPKRSETAKGFELLYQPDVVRLYLSILTESQNFNTLEAAAGALQNLSAGNWTWSTYIRATVRKERGLPVLVELLQSDSDKVVRAVSIALRNLSMDRRNKDLIGSYAMGELVRNLPSRQQRSAKNLEEDTVVAVLNTIHEIITDSSENARSLIQTQGIQKLVAISKSSQSPRETKAASHVLQMIWSYKELRNALQKDGWNKSHFQSVSATPKSSKGTAGRSGYDDSTLPLVDKSQDNEKTGSRDMIPMDELGPDGYSTIDHRDKERKYKTSDNTGDASEKEPLKG", "length": 957, "header": "tr|A0A8V1A0V6-1|A0A8V0ZTI6_CHICK Computationally mapped isoform of Armadillo repeat deleted in velocardiofacial syndrome OS=Gallus gallus OX=9031 GN=ARVCF PE=1 SV=1 CANONICAL=A0A8V0ZTI6-1" }, "locus": { "chromosome": "15", "start_pos": 1204278, "end_pos": 1080596, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010060076.1", "url": "https://www.ensembl.org/id/ENSGALT00010060076.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036836.1", "url": "https://www.ensembl.org/id/ENSGALP00010036836.1" } ] } }, { "isoform_ac": "A0A8V1A671-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTI6/entry#A0A8V1A671-1", "sequence": { "sequence": "MDDYDIRSAASILASVKEQEARFERLTRALEEERRNVSLQLERANQPADRMSICNIGNGQPLATAWQQLVLQMKDLACTSDSYVHEQSPSNQTSIAMMQEPQEMVEETVTVEEDPGTPTSHVSIVTSEDGTTRRTETKVTKMVKTVTTRTVRQVPLGPDGLPSMDGSSPMGSYTDSIDRRYMKNGERYITPQASSTLTRSYNSYNDSYPDGHEGQYRPYISHDGYGDLADNYGSLSRGVNYRPRYAYVPGNSYRPDDGSFTLPSRRDNYGPVAQPQVPVGSSVDLNRSQPERFQPEPYGLEDDNRSLGVDDEGYELDPDYSTVNRRTSAGVPERGRPHKGRGYDDPIETEMVEERIPYLHGSYAAPLAQPERGSMASIDRLGKRSPSIDSIRKDPRWRDPDLPEVIAMLSHPIDPVKSNAAAYLQHLCYENDKIKKDVRHLKGIPILVGLLDHPKPEVHRKACGALRNISYGKDNENKVAIKNCDGIPALIRLLRKTNDMEVRELITGTLWNLSSYEPLKMVIINHGLQTLTNEVIIPHSGWESEPNEDSKPRDAEWTTVFKNTSGCLRNVSSDGAEARRRLRECDGLVDALLHALQSAVGKKDTDNKSVENCVCIMRNLSYHVHKEVPGADKYQELDAGQTAGTGGSQKKKKDDAGCFGGKKAKGKKNGDLDRSFDTLDLPKRSETAKGFELLYQPDVVRLYLSILTESQNFNTLEAAAGALQNLSAGNWTWSTYIRATVRKERGLPVLVELLQSDSDKVVRAVSIALRNLSMDRRNKDLIGSYAMGELVRNLPSRQQRSAKNLEEDTVVAVLNTIHEIITDSSENARSLIQTQGIQKLVAISKSSQSPRETKAASHVLQMIWSYKELRNALQKDGWNKSHFQSVSATPKSSKGTAGRSGYDDSTLPLVDKSQDNEKTGSRDMIPMDELGPDGYSTIDHRDKERKYKTSDNTGDASEKEPLKG", "length": 964, "header": "tr|A0A8V1A671-1|A0A8V0ZTI6_CHICK Computationally mapped isoform of Armadillo repeat deleted in velocardiofacial syndrome OS=Gallus gallus OX=9031 GN=ARVCF PE=1 SV=1 CANONICAL=A0A8V0ZTI6-1" }, "locus": { "chromosome": "15", "start_pos": 1204278, "end_pos": 1080596, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010060079.1", "url": "https://www.ensembl.org/id/ENSGALT00010060079.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036839.1", "url": "https://www.ensembl.org/id/ENSGALP00010036839.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTI6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTI6" } ], "pmid": "" 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"database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHT2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHT2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHT2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHT2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQTQENQYLPFRSLFLQGKSISQLLLLRACSTVGIKQLCVLEAAGDNHRRARCFLSVHPEGDKHEPTGTTPVMWNVSSMLMEGTACTARCLRCEPKEQLGDPTGWRSSTSGCPARCSEHTDAVSVDNCVHSFPAEITGNKRSRVRSPALGINTNPSPSGKKFRSKPQLARYLGSSMDLSTFDFRTGKMLMSKMNKNRQRMRYDCSNQAKGKPDLNTALPVRQTASIFKQPVTKITNHPSNKVKSDPQKAVDQPRQLFWEKKLSGLNAFDIAEELVKTMDLPKGLQGVGPGCTDETLLSAIASALHTSTMPITGQLSAAVEKNPGVWLNTSQPLCKAFMVTDEDIRKQEELVQQVRKRLEEALMADMLAHVEEIARDGEAPTEKEGGEEEGEDEEEEEEQDHDQEMENV", "length": 408, "header": "tr|A0A8V1AFX7-1|A0A8V1AFX7_CHICK Isoform 1 of Methyl-CpG binding domain protein 3 OS=Gallus gallus OX=9031 GN=MBD3 PE=1 SV=1 CANONICAL=A0A8V1AFX7-1" }, "isoforms": [ { "isoform_ac": "A0A3Q3AW20-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFX7/entry#A0A3Q3AW20-1", "sequence": { "sequence": "MPKAALPGQRGGARRQAVGCSEHTDAVSVDNCVHSFPAEITGNKRSRVRSPALGINTNPSPSGKKFRSKPQLARYLGSSMDLSTFDFRTGKMLMSKMNKNRQRMRYDCSNQAKGKPDLNTALPVRQTASIFKQPVTKITNHPSNKVKSDPQKAVDQPRQLFWEKKLSGLNAFDIAEELVKTMDLPKGLQGVGPGCTDETLLSAIASALHTSTMPITGQLSAAVEKNPGVWLNTSQPLCKAFMVTDEDIRKQEELVQQVRKRLEEALMADMLAHVEEIARDGEAPTEKEGGEEEGEDEEEEEEQDHDQEMENV", "length": 312, "header": "tr|A0A3Q3AW20-1|A0A8V1AFX7_CHICK Computationally mapped isoform of Methyl-CpG binding domain protein 3 OS=Gallus gallus OX=9031 GN=MBD3 PE=1 SV=1 CANONICAL=A0A8V1AFX7-1" }, "locus": { "chromosome": "28", "start_pos": 2877042, "end_pos": 2864761, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067367.1", "url": "https://www.ensembl.org/id/ENSGALT00010067367.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041209.1", "url": "https://www.ensembl.org/id/ENSGALP00010041209.1" } ] } }, { "isoform_ac": "A0A8V1AAI5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFX7/entry#A0A8V1AAI5-1", "sequence": { "sequence": "MKRQATSGGSCPSGKKFRSKPQLARYLGSSMDLSTFDFRTGKMLMSKMNKNRQRMRYDCSNQAKGKPDLNTALPVRQTASIFKQPVTKITNHPSNKVKSDPQKAVDQPRQLFWEKKLSGLNAFDIAEELVKTMDLPKGLQGVGPGCTDETLLSAIASALHTSTMPITGQLSAAVEKNPGVWLNTSQPLCKAFMVTDEDIRKQEELVQQVRKRLEEALMADMLAHVEEIARDGEAPTEKEGGEEEGEDEEEEEEQDHDQEMENV", "length": 263, "header": "tr|A0A8V1AAI5-1|A0A8V1AFX7_CHICK Computationally mapped isoform of Methyl-CpG binding domain protein 3 OS=Gallus gallus OX=9031 GN=MBD3 PE=1 SV=1 CANONICAL=A0A8V1AFX7-1" }, "locus": { "chromosome": "28", "start_pos": 2877042, "end_pos": 2868400, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067356.1", "url": "https://www.ensembl.org/id/ENSGALT00010067356.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041201.1", "url": "https://www.ensembl.org/id/ENSGALP00010041201.1" } ] } }, { "isoform_ac": "A0A8V1AAJ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFX7/entry#A0A8V1AAJ0-1", "sequence": { "sequence": "MIPTRCPYPLAVLHSSGSDGCWVLWVSAGGSHHPSCSEHTDAVSVDNCVHSFPAEITGNKRSRVRSPALGINTNPSPSGKKFRSKPQLARYLGSSMDLSTFDFRTGKMLMSKMNKNRQRMRYDCSNQAKGKPDLNTALPVRQTASIFKQPVTKITNHPSNKVKSDPQKAVDQPRQLFWEKKLSGLNAFDIAEELVKTMDLPKGLQGVGPGCTDETLLSAIASALHTSTMPITGQLSAAVEKNPGVWLNTSQPLCKAFMVTDEDIRKQEELVQQVRKRLEEALMADMLAHVEEIARDGEAPTEKEGGEEEGEDEEEEEEQDHDQEMENV", "length": 328, "header": "tr|A0A8V1AAJ0-1|A0A8V1AFX7_CHICK Computationally mapped isoform of Methyl-CpG binding domain protein 3 OS=Gallus gallus OX=9031 GN=MBD3 PE=1 SV=1 CANONICAL=A0A8V1AFX7-1" }, "locus": { "chromosome": "28", "start_pos": 2877042, "end_pos": 2866460, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067363.1", "url": "https://www.ensembl.org/id/ENSGALT00010067363.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041206.1", "url": "https://www.ensembl.org/id/ENSGALP00010041206.1" } ] } }, { "isoform_ac": "A0A8V1ADB1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFX7/entry#A0A8V1ADB1-1", "sequence": { "sequence": "MLQRCSEHTDAVSVDNCVHSFPAEITGNKRSRVRSPALGINTNPSPSGKKFRSKPQLARYLGSSMDLSTFDFRTGKMLMSKMNKNRQRMRYDCSNQAKGKPDLNTALPVRQTASIFKQPVTKITNHPSNKVKSDPQKAVDQPRQLFWEKKLSGLNAFDIAEELVKTMDLPKGLQGVGPGCTDETLLSAIASALHTSTMPITGQLSAAVEKNPGVWLNTSQPLCKAFMVTDEDIRKQEELVQQVRKRLEEALMADMLAHVEEIARDGEAPTEKEGGEEEGEDEEEEEEQDHDQEMENV", "length": 297, "header": "tr|A0A8V1ADB1-1|A0A8V1AFX7_CHICK Computationally mapped isoform of Methyl-CpG binding domain protein 3 OS=Gallus gallus OX=9031 GN=MBD3 PE=1 SV=1 CANONICAL=A0A8V1AFX7-1" }, "locus": { "chromosome": "28", "start_pos": 2877042, "end_pos": 2866874, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067358.1", "url": "https://www.ensembl.org/id/ENSGALT00010067358.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041203.1", "url": "https://www.ensembl.org/id/ENSGALP00010041203.1" } ] } }, { "isoform_ac": "A0A8V1ADB6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFX7/entry#A0A8V1ADB6-1", "sequence": { "sequence": "MPKAALPGQRGGARRQAVGCSEHTDAVSVDNCVHSFPAEITGNKRSRVRSPALGINTNPRSGEKCGRREFPARSTRTCSHIQKSPSGKKFRSKPQLARYLGSSMDLSTFDFRTGKMLMSKMNKNRQRMRYDCSNQAKGKPDLNTALPVRQTASIFKQPVTKITNHPSNKVKSDPQKAVDQPRQLFWEKKLSGLNAFDIAEELVKTMDLPKGLQGVGPGCTDETLLSAIASALHTSTMPITGQLSAAVEKNPGVWLNTSQPLCKAFMVTDEDIRKQEELVQQVRKRLEEALMADMLAHVEEIARDGEAPTEKEGGEEEGEDEEEEEEQDHDQEMENV", "length": 336, "header": "tr|A0A8V1ADB6-1|A0A8V1AFX7_CHICK Computationally mapped isoform of Methyl-CpG binding domain protein 3 OS=Gallus gallus OX=9031 GN=MBD3 PE=1 SV=1 CANONICAL=A0A8V1AFX7-1" }, "locus": { "chromosome": "28", "start_pos": 2877042, "end_pos": 2864761, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067366.1", "url": "https://www.ensembl.org/id/ENSGALT00010067366.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041208.1", "url": "https://www.ensembl.org/id/ENSGALP00010041208.1" } ] } }, { "isoform_ac": "A0A8V1AFX2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFX7/entry#A0A8V1AFX2-1", "sequence": { "sequence": "MERKSCSEHTDAVSVDNCVHSFPAEITGNKRSRVRSPALGINTNPSGKKFRSKPQLARYLGSSMDLSTFDFRTGKMLMSKMNKNRQRMRYDCSNQAKGKPDLNTALPVRQTASIFKQPVTKITNHPSNKVKSDPQKAVDQPRQLFWEKKLSGLNAFDIAEELVKTMDLPKGLQGVGPGCTDETLLSAIASALHTSTMPITGQLSAAVEKNPGVWLNTSQPLCKAFMVTDEDIRKQEELVQQVRKRLEEALMADMLAHVEEIARDGEAPTEKEGGEEEGEDEEEEEEQDHDQEMENV", "length": 296, "header": "tr|A0A8V1AFX2-1|A0A8V1AFX2_CHICK Computationally mapped isoform of Methyl-CpG binding domain protein 3 OS=Gallus gallus OX=9031 GN=MBD3 PE=1 SV=1 CANONICAL=A0A8V1AFX7-1" }, "locus": { "chromosome": "28", "start_pos": 2877042, "end_pos": 2865961, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067364.1", "url": "https://www.ensembl.org/id/ENSGALT00010067364.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041207.1", "url": "https://www.ensembl.org/id/ENSGALP00010041207.1" } ] } }, { "isoform_ac": "A0A8V1AFX7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFX7/entry#A0A8V1AFX7-1", "sequence": { "sequence": "MQTQENQYLPFRSLFLQGKSISQLLLLRACSTVGIKQLCVLEAAGDNHRRARCFLSVHPEGDKHEPTGTTPVMWNVSSMLMEGTACTARCLRCEPKEQLGDPTGWRSSTSGCPARCSEHTDAVSVDNCVHSFPAEITGNKRSRVRSPALGINTNPSPSGKKFRSKPQLARYLGSSMDLSTFDFRTGKMLMSKMNKNRQRMRYDCSNQAKGKPDLNTALPVRQTASIFKQPVTKITNHPSNKVKSDPQKAVDQPRQLFWEKKLSGLNAFDIAEELVKTMDLPKGLQGVGPGCTDETLLSAIASALHTSTMPITGQLSAAVEKNPGVWLNTSQPLCKAFMVTDEDIRKQEELVQQVRKRLEEALMADMLAHVEEIARDGEAPTEKEGGEEEGEDEEEEEEQDHDQEMENV", "length": 408, "header": "tr|A0A8V1AFX7-1|A0A8V1AFX7_CHICK Isoform 1 of Methyl-CpG binding domain protein 3 OS=Gallus gallus OX=9031 GN=MBD3 PE=1 SV=1 CANONICAL=A0A8V1AFX7-1" }, "locus": { "chromosome": "28", "start_pos": 2877042, "end_pos": 2862406, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067371.1", "url": "https://www.ensembl.org/id/ENSGALT00010067371.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041212.1", "url": "https://www.ensembl.org/id/ENSGALP00010041212.1" } ] } }, { "isoform_ac": "A0A8V1AHS3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFX7/entry#A0A8V1AHS3-1", "sequence": { "sequence": "MGAAALRRGSSILPFMQQELFFSTSLTAAKALPRTLLELVLPLGITTYSSLCVLKQWFQIGCLDPVCSCLLLPALMPSSGLSVLQLAASRPACRQGWSPSSSDILNLQLAPGGIGTSSVLICVQQVPSGKKFRSKPQLARYLGSSMDLSTFDFRTGKMLMSKMNKNRQRMRYDCSNQAKGKPDLNTALPVRQTASIFKQPVTKITNHPSNKVKSDPQKAVDQPRQLFWEKKLSGLNAFDIAEELVKTMDLPKGLQGVGPGCTDETLLSAIASALHTSTMPITGQLSAAVEKNPGVWLNTSQPLCKAFMVTDEDIRKQEELVQQVRKRLEEALMADMLAHVEEIARDGEAPTEKEGGEEEGEDEEEEEEQDHDQEMENV", "length": 378, "header": "tr|A0A8V1AHS3-1|A0A8V1AFX7_CHICK Computationally mapped isoform of Methyl-CpG binding domain protein 3 OS=Gallus gallus OX=9031 GN=MBD3 PE=1 SV=1 CANONICAL=A0A8V1AFX7-1" }, "locus": { "chromosome": "28", "start_pos": 2877042, "end_pos": 2869503, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067354.1", "url": "https://www.ensembl.org/id/ENSGALT00010067354.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041200.1", "url": "https://www.ensembl.org/id/ENSGALP00010041200.1" } ] } }, { "isoform_ac": "A0A8V1AHS7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFX7/entry#A0A8V1AHS7-1", "sequence": { "sequence": "MNTSAISACCLPGCFLSPSCSEHTDAVSVDNCVHSFPAEITGNKRSRVRSPALGINTNPSPSGKKFRSKPQLARYLGSSMDLSTFDFRTGKMLMSKMNKNRQRMRYDCSNQAKGKPDLNTALPVRQTASIFKQPVTKITNHPSNKVKSDPQKAVDQPRQLFWEKKLSGLNAFDIAEELVKTMDLPKGLQGVGPGCTDETLLSAIASALHTSTMPITGQLSAAVEKNPGVWLNTSQPLCKAFMVTDEDIRKQEELVQQVRKRLEEALMADMLAHVEEIARDGEAPTEKEGGEEEGEDEEEEEEQDHDQEMENV", "length": 312, "header": "tr|A0A8V1AHS7-1|A0A8V1AFX7_CHICK Computationally mapped isoform of Methyl-CpG binding domain protein 3 OS=Gallus gallus OX=9031 GN=MBD3 PE=1 SV=1 CANONICAL=A0A8V1AFX7-1" }, "locus": { "chromosome": "28", "start_pos": 2877042, "end_pos": 2867243, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067361.1", "url": "https://www.ensembl.org/id/ENSGALT00010067361.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041205.1", "url": "https://www.ensembl.org/id/ENSGALP00010041205.1" } ] } }, { "isoform_ac": "A0A8V1AHT2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFX7/entry#A0A8V1AHT2-1", "sequence": { "sequence": "MQTQENQYLPFRSLFLQGKSISQLLLLRACSTVGIKQVGISSCSEHTDAVSVDNCVHSFPAEITGNKRSRVRSPALGINTNPSPSGKKFRSKPQLARYLGSSMDLSTFDFRTGKMLMSKMNKNRQRMRYDCSNQAKGKPDLNTALPVRQTASIFKQPVTKITNHPSNKVKSDPQKAVDQPRQLFWEKKLSGLNAFDIAEELVKTMDLPKGLQGVGPGCTDETLLSAIASALHTSTMPITGQLSAAVEKNPGVWLNTSQPLCKAFMVTDEDIRKQEELVQQVRKRLEEALMADMLAHVEEIARDGEAPTEKEGGEEEGEDEEEEEEQDHDQEMENV", "length": 335, "header": "tr|A0A8V1AHT2-1|A0A8V1AFX7_CHICK Computationally mapped isoform of Methyl-CpG binding domain protein 3 OS=Gallus gallus OX=9031 GN=MBD3 PE=1 SV=1 CANONICAL=A0A8V1AFX7-1" }, "locus": { "chromosome": "28", "start_pos": 2877042, "end_pos": 2862406, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067369.1", "url": "https://www.ensembl.org/id/ENSGALT00010067369.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041210.1", "url": "https://www.ensembl.org/id/ENSGALP00010041210.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-6804758", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6804758", "resource": "Reactome", "description": "Regulation of TP53 Activity through Acetylation" }, { "id": "R-GGA-73762", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-73762", "resource": "Reactome", "description": "RNA Polymerase I Transcription Initiation" }, { "id": "R-GGA-8943724", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8943724", "resource": "Reactome", "description": "Regulation of PTEN gene transcription" }, { "id": "R-GGA-9937850", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9937850", "resource": "Reactome", "description": "NuRD complex assembly" }, { "id": "R-GGA-9940951", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9940951", "resource": "Reactome", "description": "Interaction of NuRD complexes with transcription factors" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFX7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFX7" } ], "pmid": "" }, { "name": "methyl-CpG binding", "id": "GO:0008327", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008327", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFX7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFX7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFX7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFX7" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFX7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFX7" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFX7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFX7" } ], "pmid": "" }, { "name": "heterochromatin", "id": "GO:0000792", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000792", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFX7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFX7" } ], "pmid": "" }, { "name": "NuRD complex", "id": "GO:0016581", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016581", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFX7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFX7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFX7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFX7" } ], "pmid": "" }, { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFX7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFX7" } ], "pmid": "" }, { "name": "DNA methylation-dependent constitutive heterochromatin formation", "id": "GO:0006346", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006346", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFX7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFX7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 328, "end_pos": 330, "annotation": "n_glycosylation_sequon" }, { "start_pos": 75, "end_pos": 77, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AFX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFX7" }, { "id": "PS50982", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50982" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "MBD", "eco_id": "ECO_0000259", "start_pos": 91, "end_pos": 188, "start_aa": "Leu", "end_aa": "Met", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 328, "end_pos": 330 }, { "start_pos": 75, "end_pos": 77 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZST4-1", "uniprot_ac": "A0A8V0ZST4", "uniprot_id": "A0A8V0ZST4_CHICK", "mass": { "chemical_mass": 67599.0, "monoisotopic_mass": 67599.0 }, "refseq": {}, "gene_names": [ { "name": "ATG16L2", "type": "recommended", "evidence": [ { "id": "A0A8V0ZST4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZST4" } ] } ], "protein_names": [ { "name": "Autophagy related 16 like 2", "type": "synonym", "evidence": [ { "id": "A0A8V0ZST4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZST4/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZST4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZST4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ATG16L2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZST4", "locus": {} } ], "crossref": [ { "id": "A0A8V0ZST4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZST4", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00200", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00200", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd22887", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22887", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "424746", "url": "https://www.ncbi.nlm.nih.gov/gene/424746", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013923", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013923", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019775", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019775", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020472", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020472", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045160", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045160", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "WGRPCIS", "url": "https://omabrowser.org/oma/group/WGRPCIS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZQW9", "url": "https://www.orthodb.org/?gene=A0A8V0ZQW9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZST4", "url": "https://www.orthodb.org/?gene=A0A8V0ZST4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZYB6", "url": "https://www.orthodb.org/?gene=A0A8V0ZYB6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19878", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19878", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19878:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19878:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00400", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00400", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08614", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08614", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-1632852", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1632852", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZQW9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQW9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQW9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQW9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZST4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZST4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZST4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZST4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZYB6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYB6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZYB6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYB6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASGLHAAGFPPWKRHIAAELRRRDRLQRQAFEEIVAQYNKLLEKSDLHAVLADKLQAEKYDMQSRHEISPGHDGTWNDAQLQELAQLKIKHQEELTELHKKRGELAQSVIDLNNQMQQKDKEMQMNEAKIAEYLQKISELETECQELRSKLQDLERANQTLKDEYDALQITFNALEEKLRKTTEDNQELVSRWMAEKAQEANRLNAENEKDSRRRQARLQKELAEAAKEPLPVEPRDDDIEVLADETSDTAEETSPVRAVSRTPSKRLSQPAGGLLDSITNIFGRRSLSSFPPPQDNAEPHPGASKEVRVPTTAICVFDAHDGEVNAVQFSPGSRLLATGGMDRRVKLWEVLGDRCEPKGSLSGSNAGITSIEFDSAGSYLLAASNDFASRIWTVDDNRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWDLRSKVLFAGSSCNDIVCTEQCVMSGHFDKKIRFWDIRTESIVKELELLGRITALDLNSERTELLTCSRDDLLKIIDLRVGAVKQTFSAQGFKCGSDWTRVVFSPDGNYVAAGSADGALYVWNVLTGKLERTLAKHHSSPINAVAWSPAGAHVVSVDKGNKAVLWSEF", "length": 604, "header": "tr|A0A8V0ZST4-1|A0A8V0ZST4_CHICK Isoform 1 of Autophagy related 16 like 2 OS=Gallus gallus OX=9031 GN=ATG16L2 PE=1 SV=1 CANONICAL=A0A8V0ZST4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZQW9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZST4/entry#A0A8V0ZQW9-1", "sequence": { "sequence": "MASGLHAAGFPPWKRHIAAELRRRDRLQRQAFEEIVAQYNKLLEKSDLHAVLADKLQAEKYDMQSRHEISPGHDGTWNDAQLQELAQLKIKHQEELTELHKKRGELAQSVIDLNNQMQQKDKEMQMNEAKIAEYLQKISELETECQELRSKLQDLERANQTLKDEYDALQITFNALEEKLRKTTEDNQELVSRWMAEKAQEANRLNAENEKDSRRRQARLQKELAEAAKEPLPVEPRDDDIEVLADETSDTAEETSPVRAVSRTPSKRLSQPAGGLLDSITNIFGRRSLSSFPPPQDNAEPHPGASKEVRVPTTAICVFDAHDGEVNAVQFSPGSRLLATGGMDRRVKLWEVLGDRCEPKGSLSGSNAGITSIEFDSAGSYLLAASNDFASRIWTVDDNRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWDLRSKVCIKTVFAGSSCNDIVCTEQCVMSGHFDKKIRFWDIRTESIVKELELLGRITALDLNSERTELLTCSRDDLLKIIDLRVGAVKQTFSAQGFKCGSDWTRVVFSSPINAVAWSPAGAHVVSVDKGNKAVLWSEF", "length": 574, "header": "tr|A0A8V0ZQW9-1|A0A8V0ZQW9_CHICK Computationally mapped isoform of Autophagy related 16 like 2 OS=Gallus gallus OX=9031 GN=ATG16L2 PE=1 SV=1 CANONICAL=A0A8V0ZST4-1" }, "locus": { "chromosome": "9", "start_pos": 821716, "end_pos": 802925, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056026.1", "url": "https://www.ensembl.org/id/ENSGALT00010056026.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033900.1", "url": "https://www.ensembl.org/id/ENSGALP00010033900.1" } ] } }, { "isoform_ac": "A0A8V0ZST4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZST4/entry#A0A8V0ZST4-1", "sequence": { "sequence": "MASGLHAAGFPPWKRHIAAELRRRDRLQRQAFEEIVAQYNKLLEKSDLHAVLADKLQAEKYDMQSRHEISPGHDGTWNDAQLQELAQLKIKHQEELTELHKKRGELAQSVIDLNNQMQQKDKEMQMNEAKIAEYLQKISELETECQELRSKLQDLERANQTLKDEYDALQITFNALEEKLRKTTEDNQELVSRWMAEKAQEANRLNAENEKDSRRRQARLQKELAEAAKEPLPVEPRDDDIEVLADETSDTAEETSPVRAVSRTPSKRLSQPAGGLLDSITNIFGRRSLSSFPPPQDNAEPHPGASKEVRVPTTAICVFDAHDGEVNAVQFSPGSRLLATGGMDRRVKLWEVLGDRCEPKGSLSGSNAGITSIEFDSAGSYLLAASNDFASRIWTVDDNRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWDLRSKVLFAGSSCNDIVCTEQCVMSGHFDKKIRFWDIRTESIVKELELLGRITALDLNSERTELLTCSRDDLLKIIDLRVGAVKQTFSAQGFKCGSDWTRVVFSPDGNYVAAGSADGALYVWNVLTGKLERTLAKHHSSPINAVAWSPAGAHVVSVDKGNKAVLWSEF", "length": 604, "header": "tr|A0A8V0ZST4-1|A0A8V0ZST4_CHICK Isoform 1 of Autophagy related 16 like 2 OS=Gallus gallus OX=9031 GN=ATG16L2 PE=1 SV=1 CANONICAL=A0A8V0ZST4-1" }, "locus": { "chromosome": "9", "start_pos": 821716, "end_pos": 802925, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056021.1", "url": "https://www.ensembl.org/id/ENSGALT00010056021.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033897.1", "url": "https://www.ensembl.org/id/ENSGALP00010033897.1" } ] } }, { "isoform_ac": "A0A8V0ZYB6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZST4/entry#A0A8V0ZYB6-1", "sequence": { "sequence": "MASGLHAAGFPPWKRHIAAELRRRDRLQRQAFEEIVAQYNKLLEKSDLHAVLADKLQAEKYDMQSRHEISPGHDGTWNDAQLQELAQLKIKHQEELTELHKKRGELAQSVIDLNNQMQQKDKEMQMNEAKIAEYLQKISELETECQELRSKLQDLERANQTLKDEYDALQITFNALEEKLRKTTEDNQELVSRWMAEKAQEANRLNAENEKDSRRRQARLQKELAEAAKEPLPVEPRDDDIEVLADETSDTAEETSPVRAVSRTPSKRLSQPAGGLLDSITNIFGLSESPLLGHQSSDAARRRSLSSFPPPQDNAEPHPGASKEVRVPTTAICVFDAHDGEVNAVQFSPGSRLLATGGMDRRVKLWEVLGDRCEPKGSLSGSNAGITSIEFDSAGSYLLAASNDFASRIWTVDDNRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWDLRSKVCIKTVFAGSSCNDIVCTEQCVMSGHFDKKIRFWDIRTESIVKELELLGRITALDLNSERTELLTCSRDDLLKIIDLRVGAVKQTFSAQGFKCGSDWTRVVFSPDGNYVAAGSADGALYVWNVLTGKLERTLAKHHSSPINAVAWSPAGAHVVSVDKGNKAVLWSEF", "length": 624, "header": "tr|A0A8V0ZYB6-1|A0A8V0ZST4_CHICK Computationally mapped isoform of Autophagy related 16 like 2 OS=Gallus gallus OX=9031 GN=ATG16L2 PE=1 SV=1 CANONICAL=A0A8V0ZST4-1" }, "locus": { "chromosome": "9", "start_pos": 821716, "end_pos": 802925, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056016.1", "url": "https://www.ensembl.org/id/ENSGALT00010056016.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033894.1", "url": "https://www.ensembl.org/id/ENSGALP00010033894.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-1632852", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1632852", "resource": "Reactome", "description": "Macroautophagy" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1M3D1-1", "protein_name": "Autophagy related 16 like 1", "gene_name": "ATG16L1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSSGLRAAVFPRWKRHISEELRRRDRLQRQAFEEIILQYNKLLEKSDLHSVLAHKLQAEKHDVPNRHEISPGHDGSWNDSQLQEMAQLRIKHQEELTELHKKRGELAQLVIDLNNQMQQKDKEMQMNEAKIAEYLQTISDLETECQELRTKLQDLERANQTLKDEYDALQITFTALEEKLRKTSEENQELVTRWMAEKAQEANRLNAENEKDSRRRQARLQKELAEAAKEPLPVEQDDDIEVLVDETSEHPEETSPVRAISRAATKRLSQPAGGLLDSITNIFGRRSVSSFPVPQDNVDPHPGAGKEVRVPTTAMSVFDAHDGEVNAVQFSPGSRLLATGGMDRRVKLWEVFGDKCEFKGSLSGSNAGITSIEFDSAGSYLLAASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWDLRSKVCIKTVFAGSSCNDIVCTEQCVMSGHFDKKIRFWDIRSESIVREMELLGKITALDLNPERTELLSCSRDDLLKIIDLRINAVRQTFSAPGFKCGSDWTRAVFSPDGSYVAAGAAEGSLYIWNVLSGKVEKVLSKHHSSSINAVAWSPAGSHVVTVDKGSKAVLWSEY", "length": 607 }, "evidence": [ { "id": "A0A8V0ZST4", "url": "https://omabrowser.org/oma/group/A0A8V0ZST4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "B7Z0R7-1", "protein_name": "Autophagy-related 16, isoform F", "gene_name": "Atg16", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSTEEHVWRAHVVRRLRERNRKECDNFKEIIEQNNRLIDHVAQLKADNLKISVENEQLRNAVSTGGTGSNVAIATLEKKLLSQQEELTELHKRKGENSQMIVDLNQKVEQQRIIISEKEHSLVEQQTNNNRLRAEVQLLHSSLEELKKLNNTMLDEHTALQLAFSSLEEKLRGVQDENRRLLERLMQYKSKDADKLNEENESIIRKRLPSIFRKRSAKLKRDLEDAVREPSSSSNAASSPGAASLQRNSSPAQFVGGLIGDEDFDEAAINGAMEAIGLDDNEYISARFTAGEIAENSRASIDTLKATGYLGQANPTKILMKFEAHENESHAVRWSPVERMVATGGADRKVKLWDIGKNSTEPRAVLSGSSAGINSVDFDSTGAYILGTSNDYGARVWTVMDNRLRHTLTGHSGKVMAAKYVQEPIKVVTGSHDRTLKIWDLRSIACIETKFAGSSCNDLVTTDSLGSTIISGHYDKKIRFWDIRTEKQADDVLMPAKITSLDLSKDCNYLICSVRDDTIKLLDLRKNQVISTFTNEHFKISCDFARASFNSSGLKIACGSADGAIYIWNVNGFLEATLKGHSTAVNAVSWSPNNNMLASVGKNKRCTIYSES", "length": 612 }, "evidence": [ { "id": "A0A8V0ZST4", "url": "https://omabrowser.org/oma/group/A0A8V0ZST4/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "D3ZFK6-1", "protein_name": "Autophagy-related protein 16-1", "gene_name": "Atg16l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSGLRAADFPRWKRHIAEELRRRDRLQRQAFEEIILQYTKLLEKSDLHSVLTQKLQAEKHDVPNRHEISPGHDGAWNDSQLQEMAQLKMKHQEELTELHKKRGELAQLVIDLNNQMQQKDKEIQTNEAKIAECLQTISDLEADCLDLRTKLQDLEVANQTLKDEYDALQITFTALEEKLRKTTEENQELVTRWMAEKAQEANRLNAENEKDSRRRQARLQKELAEAAKEPLPVEQDDDIEVIVDETSDHTEETSPVRAISRAATKRLSQPAGGLLDSITNIFGRRSVSSIPVPQDVVDTHPASGKDVRVPTTASYVFDAHDGEVNAVQFSPGSRLLATGGMDRRVKLWEAFGDKCEFKGSLSGSNAGITSIEFDSAGAYLLAASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWDLRSKVCIKTVFAGSSCNDIVCTEQCVMSGHFDKKIRFWDIRSESVVREMELLGKITALDLNPERTELLSCSRDDLLKIIDLRTNAIKQSFSAPGFKCGSDWTRVVFSPDGSYVAAGSADGSLYVWSVLTGKVEKVLSKQHSSSINAVAWAPSGLHVVSVDKGSRAVLWAQP", "length": 607 }, "evidence": [ { "id": "A0A8V0ZST4", "url": "https://omabrowser.org/oma/group/A0A8V0ZST4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1SM42-1", "protein_name": "Autophagy related 16 like 1", "gene_name": "ATG16L1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSSSLRAAVFPRWKRHISEELRRRDRLQRQAFEEIILQYNKLLEKSDLHSVLAHKLQAEKHDIPNRHEISPGHDGAWNDSQLQEMAQLRIKHQEELTELHKKRGELAQLVIDLNNQMQQRDKEMQVNEAKIAECLQTISDLETECLELRTKLQDLERANQTLKDEYDALQITFTALEEKLRKTTEENQELVTRWMAEKAQEANRLNAENEKDSRRRQARLQKELAEAAKEPLPVEQDDDIEVLADDTSDHPEETSPVRAISRAATKRLSQPAGGLLDSITNIFGRRSFSSVPAPQDNVDTHPGSSKEVRVPVTAVCVFDAHDGEVNAVQFSPGSRLLATGGMDRRVKLWEVFGDKCEFKGSLSGSNAGITSIEFDSAGSYLLAASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWDLRSKVCIKTVFAGSSCNDIVCTEQCVMSGHFDKKIRFWDIRSESIVREMELLGKITALDLNPERTELLSCSRDDLLKIIDLRINAVRQTFSAPGFKCGSDWTRVVFSPDGSYVAAGSAEGSLYVWSVLSGKVEKVLSKHHSSPINAVAWSPSGAHVASVDKGSKAVLWSDY", "length": 607 }, "evidence": [ { "id": "A0A8V0ZST4", "url": "https://omabrowser.org/oma/group/A0A8V0ZST4/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O15736-1", "protein_name": "Protein tipD", "gene_name": "tipD", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MFSSQNNSYMMMMGGGGIGNINNNQFYSPIISTSAQSFNSIVEWKRDIIRQLNDRNQNQTNNYSEFMRIYTDLLKRERTLNDRTLLYEKEIVSLRNEKKTQQQPPSGSSKMDSSSSSSSSNRVSGMGSTIEEMEQKLFKLQEDLTNSYKRNADNASSILLLNDKNKDLQNELMSKEIEIERIRSTIQQDLDSIKRLEMVVIEKENVSQIIRDELSSLQTEFLHNESKVVKLEQENSSLVERWLRKKNEEASKMNEANDFYQKMVEQRDSTPAKAAVQLSESISNLVVKLPDANDVPIPIVLERGVFSSEAMLPSKAKKRWTGHNSEIYCMAFNSIGNLLATGGGDKCVKVWDVISGQQKSTLLGASQSIVSVSFSPNDESILGTSNDNSARLWNTELGRSRHTLTGHIGKVYTGKFINSNRVVTGSHDRTIKLWDLQKGYCTRTIFCFSSCNDLVILGGSGTHLASGHVDHSVRFWDSNAGEPTQVLSSIHEGQITSITNSPTNTNQILTNSRDHTLKIIDIRTFDTIRTFKDPEYRNGLNWTKASWSPDGRYIASGSIDGSICIWDATNGKTVKVLTKVHNNGSSVCCCSWSPLANIFISADKDKNIIQWE", "length": 612 }, "evidence": [ { "id": "A0A8V0ZST4", "url": "https://omabrowser.org/oma/group/A0A8V0ZST4/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q676U5-1", "protein_name": "Autophagy-related protein 16-1", "gene_name": "ATG16L1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSSGLRAADFPRWKRHISEQLRRRDRLQRQAFEEIILQYNKLLEKSDLHSVLAQKLQAEKHDVPNRHEISPGHDGTWNDNQLQEMAQLRIKHQEELTELHKKRGELAQLVIDLNNQMQRKDREMQMNEAKIAECLQTISDLETECLDLRTKLCDLERANQTLKDEYDALQITFTALEGKLRKTTEENQELVTRWMAEKAQEANRLNAENEKDSRRRQARLQKELAEAAKEPLPVEQDDDIEVIVDETSDHTEETSPVRAISRAATKRLSQPAGGLLDSITNIFGRRSVSSFPVPQDNVDTHPGSGKEVRVPATALCVFDAHDGEVNAVQFSPGSRLLATGGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIEFDSAGSYLLAASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWDLRSKVCIKTVFAGSSCNDIVCTEQCVMSGHFDKKIRFWDIRSESIVREMELLGKITALDLNPERTELLSCSRDDLLKVIDLRTNAIKQTFSAPGFKCGSDWTRVVFSPDGSYVAAGSAEGSLYIWSVLTGKVEKVLSKQHSSSINAVAWSPSGSHVVSVDKGCKAVLWAQY", "length": 607 }, "evidence": [ { "id": "A0A8V0ZST4", "url": "https://omabrowser.org/oma/group/A0A8V0ZST4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6NNP0-1", "protein_name": "Autophagy-related protein 16", "gene_name": "ATG16", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MVQEEKAMEAINDALRALRKRHLLEEGAHAPAISALSKPLISQGSEWKEKTEKLETELQQCYKAQSRLSEQLVIEVAESRTSKAILQEKELLINDLQKELTQRREDCTRLQEELEEKTKTVDVLIAENLEIRSQLEEMTSRVQKAETENKMLIDRWMLQKMQDAERLNEANDLYEEMLAKLKANGLETLARQQVDGIVRRNEDGTDHFVESTIPSTCANRIHAHEGGCGSIVFEYNSGTLFTGGQDRAVKMWDTNSGTLIKSLYGSLGNILDMAVTHDNKSVIAATSSNNLFVWDVSSGRVRHTLTGHTDKVCAVDVSKFSSRHVVSAAYDRTIKLWDLHKGYCTNTVLFTSNCNAICLSIDGLTVFSGHMDGNLRLWDIQTGKLLSEVAGHSSAVTSVSLSRNGNRILTSGRDNVHNVFDTRTLEICGTLRASGNRLASNWSRSCISPDDDYVAAGSADGSVHVWSLSKGNIVSILKEQTSPILCCSWSGIGKPLASADKNGYVCTWT", "length": 509 }, "evidence": [ { "id": "A0A8V0ZST4", "url": "https://omabrowser.org/oma/group/A0A8V0ZST4/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q8C0J2-1", "protein_name": "Autophagy-related protein 16-1", "gene_name": "Atg16l1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSGLRAADFPRWKRHIAEELRRRDRLQRQAFEEIILQYTKLLEKSDLHSVLTQKLQAEKHDMPNRHEISPGHDGAWNDSQLQEMAQLRIKHQEELTELHKKRGELAQLVIDLNNQMQQKDKEIQMNEAKISEYLQTISDLETNCLDLRTKLQDLEVANQTLKDEYDALQITFTALEEKLRKTTEENQELVTRWMAEKAQEANRLNAENEKDSRRRQARLQKELAEAAKEPLPVEQDDDIEVIVDETSDHTEETSPVRAVSRAATKRLSQPAGGLLDSITNIFGRRSVSSIPVPQDIMDTHPASGKDVRVPTTASYVFDAHDGEVNAVQFSPGSRLLATGGMDRRVKLWEAFGDKCEFKGSLSGSNAGITSIEFDSAGAYLLAASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWDLRSKVCIKTVFAGSSCNDIVCTEQCVMSGHFDKKIRFWDIRSESVVREMELLGKITALDLNPERTELLSCSRDDLLKVIDLRTNAVKQTFSAPGFKCGSDWTRVVFSPDGSYVAAGSAEGSLYVWSVLTGKVEKVLSKQHSSSINAVAWAPSGLHVVSVDKGSRAVLWAQP", "length": 607 }, "evidence": [ { "id": "A0A8V0ZST4", "url": "https://omabrowser.org/oma/group/A0A8V0ZST4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 10, "go_terms": [ { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZST4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZST4" } ], "pmid": "" }, { "name": "autophagosome membrane", "id": "GO:0000421", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000421", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZST4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZST4" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZST4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZST4" } ], "pmid": "" }, { "name": "axon", "id": "GO:0030424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030424", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZST4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZST4" } ], "pmid": "" }, { "name": "axoneme", "id": "GO:0005930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005930", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZST4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZST4" } ], "pmid": "" }, { "name": "phagophore assembly site membrane", "id": "GO:0034045", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034045", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZST4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZST4" } ], "pmid": "" }, { "name": "endolysosome membrane", "id": "GO:0036020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZST4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZST4" } ], "pmid": "" }, { "name": "Atg12-Atg5-Atg16 complex", "id": "GO:0034274", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034274", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZST4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZST4" } ], "pmid": "" }, { "name": "sperm midpiece", "id": "GO:0097225", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097225", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZST4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZST4" } ], "pmid": "" }, { "name": "vacuole-isolation membrane contact site", "id": "GO:0120095", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120095", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZST4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZST4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "autophagosome assembly", "id": "GO:0000045", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000045", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZST4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZST4" } ], "pmid": "" }, { "name": "defense response to virus", "id": "GO:0051607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051607", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZST4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZST4" } ], "pmid": "" }, { "name": "positive regulation of autophagy", "id": "GO:0010508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010508", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZST4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZST4" } ], "pmid": "" }, { "name": "protein localization to phagophore assembly site", "id": "GO:0034497", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034497", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZST4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZST4" } ], "pmid": "" }, { "name": "axonal transport", "id": "GO:0098930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098930", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZST4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZST4" } ], "pmid": "" }, { "name": "microautophagy", "id": "GO:0016237", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016237", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZST4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZST4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZST4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZST4" } ], "pmid": "" }, { "name": "GTPase binding", "id": "GO:0051020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZST4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZST4" } ], "pmid": "" }, { "name": "protein-membrane adaptor activity", "id": "GO:0043495", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043495", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZST4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZST4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 159, "end_pos": 161, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZST4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZST4" }, { "id": "PF08614", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08614" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Autophagy-related protein 16", "eco_id": "ECO_0000259", "start_pos": 16, "end_pos": 206, "start_aa": "His", "end_aa": "Asn", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 159, "end_pos": 161 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { 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0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": 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"https://www.uniprot.org/uniprotkb/A0A8V0ZU16", "locus": {} } ], "crossref": [ { "id": "A0A8V0ZU16", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZU16", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR009621", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009621", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZU16", "url": "https://www.orthodb.org/?gene=A0A8V0ZU16", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZZ80", "url": "https://www.orthodb.org/?gene=A0A8V0ZZ80", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14409", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14409", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14409:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14409:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06783", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06783", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZU16", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU16", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZU16-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU16-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZZ80", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZ80", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZZ80-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZ80-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAEVHGFSPPEIPEPTLLENVLRYGLFFGAVFQLVCVLAIILPVSRSHKPDSDSSGTKTWETVKKPKASAAQLRKKAKKESKKRQQGLG", "length": 90, "header": "tr|A0A8V0ZU16-1|A0A8V0ZU16_CHICK Isoform 1 of MANBL protein OS=Gallus gallus OX=9031 GN=MANBAL13 PE=3 SV=1 CANONICAL=A0A8V0ZU16-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZU16-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU16/entry#A0A8V0ZU16-1", "sequence": { "sequence": "MAAEVHGFSPPEIPEPTLLENVLRYGLFFGAVFQLVCVLAIILPVSRSHKPDSDSSGTKTWETVKKPKASAAQLRKKAKKESKKRQQGLG", "length": 90, "header": "tr|A0A8V0ZU16-1|A0A8V0ZU16_CHICK Isoform 1 of MANBL protein OS=Gallus gallus OX=9031 GN=MANBAL13 PE=3 SV=1 CANONICAL=A0A8V0ZU16-1" }, "locus": { "chromosome": "20", "start_pos": 1763650, "end_pos": 1754233, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010060265.1", "url": "https://www.ensembl.org/id/ENSGALT00010060265.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010037025.1", "url": "https://www.ensembl.org/id/ENSGALP00010037025.1" } ] } }, { "isoform_ac": "A0A8V0ZZ80-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU16/entry#A0A8V0ZZ80-1", "sequence": { "sequence": "MLQFEDSFPRQVVKDEAAASFVSSYVIGSVDQGYLQSTSKAATLRAVEQQAVCTMAAQRHFSPPEIPEPTLAENVLHHGLFYGAMLRLLCVLAIILPVSRSHKPDSDSSGTKTWETVKKPKASAAQLRKKAKKESKKRQQGLG", "length": 143, "header": "tr|A0A8V0ZZ80-1|A0A8V0ZU16_CHICK Computationally mapped isoform of MANBL protein OS=Gallus gallus OX=9031 GN=MANBAL13 PE=3 SV=1 CANONICAL=A0A8V0ZU16-1" }, "locus": { "chromosome": "20", "start_pos": 1755204, "end_pos": 1754233, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010060267.1", "url": "https://www.ensembl.org/id/ENSGALT00010060267.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010037027.1", "url": "https://www.ensembl.org/id/ENSGALP00010037027.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZU16", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU16" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AF03-1", "uniprot_ac": "A0A8V1AF03", "uniprot_id": "A0A8V1AF03_CHICK", "mass": { "chemical_mass": 47490.0, "monoisotopic_mass": 47490.0 }, "refseq": {}, "gene_names": [ { "name": "ACTR3B", "type": "recommended", "evidence": [ { "id": "A0A8V1AF03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF03" } ] } ], "protein_names": [ { "name": "Actin related protein 3B", "type": "synonym", "evidence": [ { "id": "A0A8V1AF03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF03/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AF03", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF03" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ACTR3B", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF03", "locus": {} } ], "crossref": [ { "id": "A0A8V1AF03", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AF03", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd10221", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd10221", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR004000", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004000", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020902", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020902", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043129", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043129", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR11937", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11937", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00022", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00022", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1A2I2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2I2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A2I2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2I2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A2J4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2J4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A2J4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2J4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A7I7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7I7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A7I7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7I7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A7J2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7J2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A7J2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7J2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AA39", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA39", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AA39-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA39-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AA46", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA46", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AA46-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA46-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AF03", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF03", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AF03-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF03-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASYLPPCVIDGGTGYTKLGYAGNTEPQFIIPSCIAIRESAKVGDQAQRRVMKGVDDLDFFIGDEAIDKPTYATKWPIRHGIVEDWDLMERFMEQVIFKYLRAEPEDHYFLMTEPPLNTPENREYLAEIMFESFNIPGLYIAVQAVLALAASWTSRQVGERTLTGIVIDSGDGVTHVIPAEGYVIGSCIKHIPIAGRDITYFIQQLLREREVGIPPEQSLETAKAIKEKYCYICPDIVKEFAKYDGDPRKWIKQYTGINAINKTKFVIDVGYERFLGPEIFFHPEFANPDFMESISDVVDEVIQNCPIDVRRPLYKNVVLSGGSTMFRDFGRRLQRDLKRVVDARLRLSEELSGGRIKPKPVEVQVITHHMQRYAVWFGGSMLASTPEFFQVCHTKKDYEEYGPSICRHNPVFGVMS", "length": 417, "header": "tr|A0A8V1AF03-1|A0A8V1AF03_CHICK Isoform 1 of Actin related protein 3B OS=Gallus gallus OX=9031 GN=ACTR3B PE=1 SV=1 CANONICAL=A0A8V1AF03-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A2I2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF03/entry#A0A8V1A2I2-1", "sequence": { "sequence": "MFKHVDQKSHLKEAAGNRYLNPNFLDLFFGEAREFPGRPETQTPLNVVLSGGSTMFRDFGRRLQRDLKRVVDARLRLSEELSGGRIKPKPVEVQVITHHMQRYAVWFGGSMLASTPEFFQVCHTKKDYEEYGPSICRHNPVFGVMS", "length": 146, "header": "tr|A0A8V1A2I2-1|A0A8V1AF03_CHICK Computationally mapped isoform of Actin related protein 3B OS=Gallus gallus OX=9031 GN=ACTR3B PE=1 SV=1 CANONICAL=A0A8V1AF03-1" }, "locus": { "chromosome": "2", "start_pos": 6844327, "end_pos": 6840685, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065829.1", "url": "https://www.ensembl.org/id/ENSGALT00010065829.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040095.1", "url": "https://www.ensembl.org/id/ENSGALP00010040095.1" } ] } }, { "isoform_ac": "A0A8V1A2J4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF03/entry#A0A8V1A2J4-1", "sequence": { "sequence": "MSVAGPESGSPNHSNVLLGTALEDGVPGPAGQRRRLWPHVLCSGYTKLGYAGNTEPQFIIPSCIAIRESAKVGDQAQRRVMKGVDDLDFFIGDEAIDKPTYATKWPIRHGIVEDWDLMERFMEQVIFKYLRAEPEDHYFLMTEPPLNTPENREYLAEIMFESFNIPGLYIAVQAVLALAASWTSRQVGERTLTGIVIDSGDGVTHVIPVAEGYVIGSCIKHIPIAGRDITYFIQQLLREREVGIPPEQSLETAKAIKEKYCYICPDIVKEFAKYDGDPRKWIKQYTGINAINKTKFVIDVGYERFLGPEIFFHPEFANPDFMESISDVVDEVIQNCPIDVRRPLYKNVVLSGGSTMFRDFGRRLQRDLKRVVDARLRLSEELSGGRIKPKPVEVQVITHHMQRYAVWFGGSMLASTPEFFQVCHTKKDYEEYGPSICRHNPVFGVMS", "length": 447, "header": "tr|A0A8V1A2J4-1|A0A8V1AF03_CHICK Computationally mapped isoform of Actin related protein 3B OS=Gallus gallus OX=9031 GN=ACTR3B PE=1 SV=1 CANONICAL=A0A8V1AF03-1" }, "locus": { "chromosome": "2", "start_pos": 6844327, "end_pos": 6825775, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065839.1", "url": "https://www.ensembl.org/id/ENSGALT00010065839.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040105.1", "url": "https://www.ensembl.org/id/ENSGALP00010040105.1" } ] } }, { "isoform_ac": "A0A8V1A7I7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF03/entry#A0A8V1A7I7-1", "sequence": { "sequence": "SCIAIRESAKVGDQAQRRVMKGVDDLDFFIGDEAIDKPTYATKWPIRHGIVEDWDLMERFMEQVIFKYLRAEPEDHYFLMTEPPLNTPENREYLAEIMFESFNIPGLYIAVQAVLALAASWTSRQVGERTLTGIVIDSGDGVTHVIPVAEGYVIGSCIKHIPIAGRDITYFIQQLLREREVGIPPEQSLETAKAIKEKYCYICPDIVKEFAKYDGDPRKWIKQYTGINAINKTKFVIDVGYERFLGPEIFFHPEFANPDFMESISDVVDEVIQNCPIDVRRPLYKNVVLSGGSTMFRDFGRRLQRDLKRVVDARLRLSEELSGGRIKPKPVEVQVITHHMQRYAVWFGGSMLASTPEFFQVCHTKKDYEEYGPSICRHNPVFGVMS", "length": 386, "header": "tr|A0A8V1A7I7-1|A0A8V1AF03_CHICK Computationally mapped isoform of Actin related protein 3B OS=Gallus gallus OX=9031 GN=ACTR3B PE=1 SV=1 CANONICAL=A0A8V1AF03-1" }, "locus": { "chromosome": "2", "start_pos": 6844327, "end_pos": 6828289, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065831.1", "url": "https://www.ensembl.org/id/ENSGALT00010065831.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040097.1", "url": "https://www.ensembl.org/id/ENSGALP00010040097.1" } ] } }, { "isoform_ac": "A0A8V1A7J2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF03/entry#A0A8V1A7J2-1", "sequence": { "sequence": "MVRKVVLLGIAIRESAKVGDQAQRRVMKGVDDLDFFIGDEAIDKPTYATKWPIRHGIVEDWDLMERFMEQVIFKYLRAEPEDHYFLMTEPPLNTPENREYLAEIMFESFNIPGLYIAVQAVLALAASWTSRQVGERTLTGIVIDSGDGVTHVIPVAEGYVIGSCIKHIPIAGRDITYFIQQLLREREVGIPPEQSLETAKAIKEKYCYICPDIVKEFAKYDGDPRKWIKQYTGINAINKTKFVIDVGYERFLGPEIFFHPEFANPDFMESISDVVDEVIQNCPIDVRRPLYKNVVLSGGSTMFRDFGRRLQRDLKRVVDARLRLSEELSGGRIKPKPVEVQVITHHMQRYAVWFGGSMLASTPEFFQVCHTKKDYEEYGPSICRHNPVFGVMS", "length": 393, "header": "tr|A0A8V1A7J2-1|A0A8V1AF03_CHICK Computationally mapped isoform of Actin related protein 3B OS=Gallus gallus OX=9031 GN=ACTR3B PE=1 SV=1 CANONICAL=A0A8V1AF03-1" }, "locus": { "chromosome": "2", "start_pos": 6844327, "end_pos": 6828727, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065836.1", "url": "https://www.ensembl.org/id/ENSGALT00010065836.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040102.1", "url": "https://www.ensembl.org/id/ENSGALP00010040102.1" } ] } }, { "isoform_ac": "A0A8V1AA39-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF03/entry#A0A8V1AA39-1", "sequence": { "sequence": "METHCTVFSGPAVMESSQEEKRHRYTKLGYAGNTEPQFIIPSCIAIRESAKVGDQAQRRVMKGVDDLDFFIGDEAIDKPTYATKWPIRHGIVEDWDLMERFMEQVIFKYLRAEPEDHYFLMTEPPLNTPENREYLAEIMFESFNIPGLYIAVQAVLALAASWTSRQVGERTLTGIVIDSGDGVTHVIPVAEGYVIGSCIKHIPIAGRDITYFIQQLLREREVGIPPEQSLETAKAIKEKYCYICPDIVKEFAKYDGDPRKWIKQYTGINAINKTKFVIDVGYERFLGPEIFFHPEFANPDFMESISDVVDEVIQNCPIDVRRPLYKNVVLSGGSTMFRDFGRRLQRDLKRVVDARLRLSEELSGGRIKPKPVEVQVITHHMQRYAVWFGGSMLASTPEFFQVCHTKKDYEEYGPSICRHNPVFGVMS", "length": 427, "header": "tr|A0A8V1AA39-1|A0A8V1AF03_CHICK Computationally mapped isoform of Actin related protein 3B OS=Gallus gallus OX=9031 GN=ACTR3B PE=1 SV=1 CANONICAL=A0A8V1AF03-1" }, "locus": { "chromosome": "2", "start_pos": 6844327, "end_pos": 6821512, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065833.1", "url": "https://www.ensembl.org/id/ENSGALT00010065833.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040099.1", "url": "https://www.ensembl.org/id/ENSGALP00010040099.1" } ] } }, { "isoform_ac": "A0A8V1AA46-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF03/entry#A0A8V1AA46-1", "sequence": { "sequence": "MYTKLGYAGNTEPQFIIPSCIAIRESAKVGDQAQRRVMKGVDDLDFFIGDEAIDKPTYATKWPIRHGIVEDWDLMERFMEQVIFKYLRAEPEDHYFLMTEPPLNTPENREYLAEIMFESFNIPGLYIAVQAVLALAASWTSRQVGERTLTGIVIDSGDGVTHVIPVAEGYVIGSCIKHIPIAGRDITYFIQQLLREREVGIPPEQSLETAKAIKEKYCYICPDIVKEFAKYDGDPRKWIKQYTGINAINKTKFVIDVGYERFLGPEIFFHPEFANPDFMESISDVVDEVIQNCPIDVRRPLYKNVVLSGGSTMFRDFGRRLQRDLKRVVDARLRLSEELSGGRIKPKPVEVQVITHHMQRYAVWFGGSMLASTPEFFQVCHTKKDYEEYGPSICRHNPVFGVMS", "length": 404, "header": "tr|A0A8V1AA46-1|A0A8V1AF03_CHICK Computationally mapped isoform of Actin related protein 3B OS=Gallus gallus OX=9031 GN=ACTR3B PE=1 SV=1 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This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052543.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. 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"evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFA6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFA6" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFA6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFA6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "CENP-A containing chromatin assembly", "id": "GO:0034080", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034080", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFA6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFA6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 101, "end_pos": 103, "annotation": "n_glycosylation_sequon" }, { "start_pos": 132, "end_pos": 134, "annotation": "n_glycosylation_sequon" }, { "start_pos": 171, "end_pos": 173, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 101, "end_pos": 103 }, { "start_pos": 132, "end_pos": 134 }, { "start_pos": 171, "end_pos": 173 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": 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"count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AFK2-1", "uniprot_ac": "A0A8V1AFK2", "uniprot_id": "A0A8V1AFK2_CHICK", "mass": { "chemical_mass": 175682.0, "monoisotopic_mass": 175682.0 }, "refseq": { "ac": "XP_418249", "name": "rho guanine nucleotide exchange factor 18 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418249" }, "gene_names": [ { "name": "ARHGEF18", "type": "recommended", "evidence": [ { "id": "A0A8V1AFK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFK2" } ] }, { "name": "ARHGEF18", "type": "synonym", "evidence": [ { "id": "XP_418249", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418249" } ] } ], "protein_names": [ { "name": "Rho/Rac guanine nucleotide exchange factor 18", "type": "synonym", "evidence": [ { "id": "A0A8V1AFK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFK2/entry#names_and_taxonomy" } ] }, { "name": "rho guanine nucleotide exchange factor 18 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_418249", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418249" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052559.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_418249.4. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_418249", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418249" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFK2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFK2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ARHGEF18", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFK2", "locus": { "chromosome": "28", "start_pos": 4518939, "end_pos": 4558811, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027244", "url": "https://www.ensembl.org/id/ENSGALG00010027244" } ] } } ], "crossref": [ { "id": "cd00160", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00160", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd15794", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15794", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "420132", "url": "https://www.ncbi.nlm.nih.gov/gene/420132", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000219", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000219", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002219", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002219", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035899", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035899", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037744", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037744", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041020", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041020", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046349", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046349", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR053089", "url": "https://www.ebi.ac.uk/interpro/entry/IPR053089", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "QSFICRR", "url": "https://omabrowser.org/oma/group/QSFICRR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A360", "url": "https://www.orthodb.org/?gene=A0A8V1A360", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AAQ5", "url": "https://www.orthodb.org/?gene=A0A8V1AAQ5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AFK2", "url": "https://www.orthodb.org/?gene=A0A8V1AFK2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47440", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47440", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47440:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47440:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00130", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00130", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00621", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00621", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17838", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17838", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_418249", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418249", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1A360", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A360", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A360-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A360-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AAQ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAQ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AAQ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAQ5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFK2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFK2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFK2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFK2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSDSLLNHSWPSFSKRWKKRWSFKRGSDCKPCLRELADRSPSALEYHSPKRFLPSLIAEDDTLFTSMAEEKEDSSSTELDVPAADLHSSTEDLLSDSALHGTEYYKDLGLLSPPANKTVPEMAARPEAAPQAASAIRLLEERSGALGKMSVDVAFSNPISCSVRYGEADCHFLNKAASTAACPAEEDEALDLQEASESFPTLVRSMSTSRRHSWESPLSPVDCKRRFSLDTTERGSDAEQEEAEKGSRSCAQPRVSLQLPGGTREAWSSSAGSMVIKVQIEPLQPSLGSEEAERASDGKRLRPLSIPSACKAASPQAPCGFNTSLSAMEGVEPPALEMLEKDHVSPDQVLMVQQVLQELKQYHGAKKRVCVQEGSDSSQQNLTWFEFLSNENEDSGKSDKAEKGTKVMRRLSSLRSRVTGSWQKDKGKNKEQSKEKEKEKETKEPKESWKEVNRHQLVPGVFSSGTSCSLCAKPLVNKSGLQCLNCAVNVHKNCKSLLAECSSIRTKQKDLQHRPSGPAQSSSQCISPAASLKEQPRSLLLGPDGTPVLPRSLGMTIAQRGTSPSSFNTAGAVSKFGLISGDMDEGDSGFIKFKQTSDDVVSLAPSTADSIFLEDAYSLSLRSEIETDAHEFEAESWSVAVEQSYAKRQKKEVVKRQDVIYELMQTEMHHVRTLKIMLKVYSKAMKEELQFSNAVINKLFPCVDELLEMHGQFLLQLKERRKESLEEGSDRNYIIQNIGDLLVKQFSGENGERMKEKYGVFCSGHNEAVSHYKDLLQSHKKFQNLIKKIGNCSIVRRLGVQECILLVTQRITKYPVLVERIIQNTEVGTKDYEDLIQALSLIKHTITHVDAIVNECEKGQRLKEIMHKMELKSSGKCKNGLFFRKDDMGQRRLLLDGMLYWKAASGRLKDILAVLLNDVLLLLQEKDQKYVFASVDSKPPVISLQKLIVREVANEEKAMFLISASLQGPEMYEIHTSSKEERNSWMAHIRRAVESCPDEEGGSFYEPETERRMAEARAAKLREFQERLNTKDDLIVQSLTEKQQIYQEMSEVYGFEDHSQGSRSRLLLGDIPESLQGEALLKSAVVEAENLQNLIFTHLGNGSCQSEESYAAGLPRRAETFGGYDSPSISNKNNSLGKSGGSDQRQWDWRGPAVSSDVQLPDLPVDAEEGSQTSDTTRQDDSSGIQPTIESQLVQRIQTLLQLLFSLQAVISQQDSYIEVQRATMVDREKQYRLQSTRGNVLLEQEKQRNFEKQREELMNVQKLQSQLKLEQQRWERERSQQQRELEISEAHLQRREEETRQLKDKLIQDREELERQREAYQHDLERLREAQRAVEKERERLDQLRKLKKQNTVSGTFSPELGQNPMQSHPVSFNGEGVEPSLPVLKASARVSVSGMDYLERSELVRRDSTTLENRPVLALKNEVPIHLLSATNQIQKPAAVQQQIPTKLATFTKGSKEKSGKNKASHRTDSSASVDQKQLIPPRLVGREEGVLRGRRSASPVLTSSQTTAFQTEIHGSANGQPEALSSASPNPFKPNNAHAQTLVTSQPTLLNMQDDTSKEDVIFF", "length": 1567, "header": "tr|A0A8V1AFK2-1|A0A8V1AFK2_CHICK Isoform 1 of Rho/Rac guanine nucleotide exchange factor 18 OS=Gallus gallus OX=9031 GN=ARHGEF18 PE=1 SV=1 CANONICAL=A0A8V1AFK2-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A360-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFK2/entry#A0A8V1A360-1", "sequence": { "sequence": "MLWSLQPGSDCKPCLRELADRSPSALEYHSPKRFLPSLIAEDDTLFTSMAEEKEDSSSTELDVPAADLHSSTEDLLSDSALHGTEYYKDLGLLSPPANKTVPEMAARPEAAPQAASAIRLLEERSGALGKMSVDVAFSNPISCSVRYGEADCHFLNKAASTAACPAEEDEALDLQEASESFPTLVRSMSTSRRHSWESPLSPVDCKRRFSLDTTERGSDAEQEEAEKGSRSCAQPRVSLQLPGGTREAWSSSAGSMVIKVQIEPLQPSLGSEEAERASDGKRLRPLSIPSACKAASPQAPCGFNTSLSAMEGVEPPALEMLEKDHVSPDQVLMVQQVLQELKQYHGAKKRVCVQEGSDSSQQNLTWFEFLSNENEDSGKSDKAEKGTKVMRRLSSLRSRVTGSWQKDKGKNKEQSKEKEKEKETKEPKESWKEVNRHQLVPGVFSSGTSCSLCAKPLVNKSGLQCLNCAVNVHKNCKSLLAECSSIRTKQKDLQHRPSGPAQSSSQCISPAASLKEQPRSLLLGPDGTPVLPRSLGMTIAQRGTSPSSFNTAGAVSKFGLISGDMDEGDSGFIKFKQTSDDVVSLAPSTADSIFLEDAYSLSLRSEIETDAHEFEAESWSVAVEQSYAKRQKKEVVKRQDVIYELMQTEMHHVRTLKIMLKVYSKAMKEELQFSNAVINKLFPCVDELLEMHGQFLLQLKERRKESLEEGSDRNYIIQNIGDLLVKQFSGENGERMKEKYGVFCSGHNEAVSHYKDLLQSHKKFQNLIKKIGNCSIVRRLGVQECILLVTQRITKYPVLVERIIQNTEVGTKDYEDLIQALSLIKHTITHVDAIVNECEKGQRLKEIMHKMELKSSGKCKNGLFFRKDDMGQRRLLLDGMLYWKAASGRLKDILAVLLNDVLLLLQEKDQKYVFASVDSKPPVISLQKLIVREVANEEKAMFLISASLQGPEMYEIHTSSKEERNSWMAHIRRAVESCPDEEGGSFYEPETERRMAEARAAKLREFQERLNTKDDLIVQSLTEKQQIYQEMSEVYGFEDHSQGSRSRLLLGDIPESLQGEALLKSAVVEAENLQNLIFTHLGNGSCQSEESYAAGLPRRAETFGGYDSPSISNKNNSLGKSGGSDQRQWDWRGPAVSSDVQLPDLPVDAEEGSQTSDTTRQDDSSGIQPTIESQLVQRIQTLLQLLFSLQAVISQQDSYIEVQRATMVDREKQYRLQSTRGNVLLEQEKQRNFEKQREELMNVQKLQSQLKLEQQRWERERSQQQRELEISEAHLQRREEETRQLKDKLIQDREELERQREAYQHDLERLREAQRAVEKERERLDQLRKLKKQNTVSGTFSPELGQNPMQSHPVSFNGEGVEPSLPVLKASARVSVSGMDYLERSELVRRDSTTLENRPVLALKNEVPIHLLSATNQIQKPAAVQQQIPTKLATFTKGSKEKSGKNKASHRTDSSASVDQKQLIPPRLVGREEGVLRGRRSASPVLTSSQTTAFQTEIHGSANGQPEALSSASPNPFKPNNAHAQTLVTSQPTLLNMQDDTSKEDVIFF", "length": 1549, "header": "tr|A0A8V1A360-1|A0A8V1AFK2_CHICK Computationally mapped isoform of Rho/Rac guanine nucleotide exchange factor 18 OS=Gallus gallus OX=9031 GN=ARHGEF18 PE=1 SV=1 CANONICAL=A0A8V1AFK2-1" }, "locus": { "chromosome": "28", "start_pos": 4558510, "end_pos": 4520395, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066052.1", "url": "https://www.ensembl.org/id/ENSGALT00010066052.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040318.1", "url": "https://www.ensembl.org/id/ENSGALP00010040318.1" } ] } }, { "isoform_ac": "A0A8V1AAQ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFK2/entry#A0A8V1AAQ5-1", "sequence": { "sequence": "MAEEKEDSSSTELDVPAADLHSSTEDLLSDSALHGTEYYKDLGLLSPPANKTVPEMAARPEAAPQAASAIRLLEERSGALGKMSVDVAFSNPISCSVRYGEADCHFLNKAASTAACPAEEDEALDLQEASESFPTLVRSMSTSRRHSWESPLSPVDCKRRFSLDTTERGSDAEQEEAEKGSRSCAQPRVSLQLPGGTREAWSSSAGSMVIKVQIEPLQPSLGSEEAERASDGKRLRPLSIPSACKAASPQAPCGFNTSLSAMEGVEPPALEMLEKDHVSPDQVLMVQQVLQELKQYHGAKKRVCVQEGSDSSQQNLTWFEFLSNENEDSGKSDKAEKGTKVMRRLSSLRSRVTGSWQKDKGKNKEQSKEKEKEKETKEPKESWKEVNRHQLVPGVFSSGTSCSLCAKPLVNKSGLQCLSEYGCRCCSDPAWLSPAPHPPAQDTRSPASISLVGFVGCFALLPGSIYPPCCLAWLGCSPDSLNDH", "length": 484, "header": "tr|A0A8V1AAQ5-1|A0A8V1AFK2_CHICK Computationally mapped isoform of Rho/Rac guanine nucleotide exchange factor 18 OS=Gallus gallus OX=9031 GN=ARHGEF18 PE=1 SV=1 CANONICAL=A0A8V1AFK2-1" }, "locus": { "chromosome": "28", "start_pos": 4553877, "end_pos": 4548900, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066051.1", "url": "https://www.ensembl.org/id/ENSGALT00010066051.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040317.1", "url": "https://www.ensembl.org/id/ENSGALP00010040317.1" } ] } }, { "isoform_ac": "A0A8V1AFK2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFK2/entry#A0A8V1AFK2-1", "sequence": { "sequence": "MSDSLLNHSWPSFSKRWKKRWSFKRGSDCKPCLRELADRSPSALEYHSPKRFLPSLIAEDDTLFTSMAEEKEDSSSTELDVPAADLHSSTEDLLSDSALHGTEYYKDLGLLSPPANKTVPEMAARPEAAPQAASAIRLLEERSGALGKMSVDVAFSNPISCSVRYGEADCHFLNKAASTAACPAEEDEALDLQEASESFPTLVRSMSTSRRHSWESPLSPVDCKRRFSLDTTERGSDAEQEEAEKGSRSCAQPRVSLQLPGGTREAWSSSAGSMVIKVQIEPLQPSLGSEEAERASDGKRLRPLSIPSACKAASPQAPCGFNTSLSAMEGVEPPALEMLEKDHVSPDQVLMVQQVLQELKQYHGAKKRVCVQEGSDSSQQNLTWFEFLSNENEDSGKSDKAEKGTKVMRRLSSLRSRVTGSWQKDKGKNKEQSKEKEKEKETKEPKESWKEVNRHQLVPGVFSSGTSCSLCAKPLVNKSGLQCLNCAVNVHKNCKSLLAECSSIRTKQKDLQHRPSGPAQSSSQCISPAASLKEQPRSLLLGPDGTPVLPRSLGMTIAQRGTSPSSFNTAGAVSKFGLISGDMDEGDSGFIKFKQTSDDVVSLAPSTADSIFLEDAYSLSLRSEIETDAHEFEAESWSVAVEQSYAKRQKKEVVKRQDVIYELMQTEMHHVRTLKIMLKVYSKAMKEELQFSNAVINKLFPCVDELLEMHGQFLLQLKERRKESLEEGSDRNYIIQNIGDLLVKQFSGENGERMKEKYGVFCSGHNEAVSHYKDLLQSHKKFQNLIKKIGNCSIVRRLGVQECILLVTQRITKYPVLVERIIQNTEVGTKDYEDLIQALSLIKHTITHVDAIVNECEKGQRLKEIMHKMELKSSGKCKNGLFFRKDDMGQRRLLLDGMLYWKAASGRLKDILAVLLNDVLLLLQEKDQKYVFASVDSKPPVISLQKLIVREVANEEKAMFLISASLQGPEMYEIHTSSKEERNSWMAHIRRAVESCPDEEGGSFYEPETERRMAEARAAKLREFQERLNTKDDLIVQSLTEKQQIYQEMSEVYGFEDHSQGSRSRLLLGDIPESLQGEALLKSAVVEAENLQNLIFTHLGNGSCQSEESYAAGLPRRAETFGGYDSPSISNKNNSLGKSGGSDQRQWDWRGPAVSSDVQLPDLPVDAEEGSQTSDTTRQDDSSGIQPTIESQLVQRIQTLLQLLFSLQAVISQQDSYIEVQRATMVDREKQYRLQSTRGNVLLEQEKQRNFEKQREELMNVQKLQSQLKLEQQRWERERSQQQRELEISEAHLQRREEETRQLKDKLIQDREELERQREAYQHDLERLREAQRAVEKERERLDQLRKLKKQNTVSGTFSPELGQNPMQSHPVSFNGEGVEPSLPVLKASARVSVSGMDYLERSELVRRDSTTLENRPVLALKNEVPIHLLSATNQIQKPAAVQQQIPTKLATFTKGSKEKSGKNKASHRTDSSASVDQKQLIPPRLVGREEGVLRGRRSASPVLTSSQTTAFQTEIHGSANGQPEALSSASPNPFKPNNAHAQTLVTSQPTLLNMQDDTSKEDVIFF", "length": 1567, "header": "tr|A0A8V1AFK2-1|A0A8V1AFK2_CHICK Isoform 1 of Rho/Rac guanine nucleotide exchange factor 18 OS=Gallus gallus OX=9031 GN=ARHGEF18 PE=1 SV=1 CANONICAL=A0A8V1AFK2-1" }, "locus": { "chromosome": "28", "start_pos": 4557830, "end_pos": 4520395, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066053.1", "url": "https://www.ensembl.org/id/ENSGALT00010066053.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040319.1", "url": "https://www.ensembl.org/id/ENSGALP00010040319.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A590UK10-1", "protein_name": "Rho guanine nucleotide exchange factor 18", "gene_name": "ARHGEF18", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "XTSVKRRLSCLRSRVTRQKEKGKSPAHLKDKGQDARERRECVNGHQLLQGTFSGPSSCPLCGKPFLSSASLKEHPRGTLLSDGSPALSRNVGMTVSQKGGPQPTPSPAGPGTQLGPITGEMDEADSAFLKFKQTADDSLSLTSPNTESIFVEDPYTASLRSEIESDGHEFEAESWSLAVDAAYAKKQKREVVKRQDVLYELMQTEVHHVRTLKIMLKVYSRALQEELQFSSKAIGRLFPCADDLLETHSHFLARLKERRQESLEEGSDRNYVIQKIGDLLVQQFSGENGERMKEKYGVFCSGHNEAVSHYKLLLQQNKKFQNLIKKIGNFSIVRRLGVQECILLVTQRITKYPVLVERIIQNTEAGTEDYEDLTQALNLIKDIISQVDAKVSECEKGQRLREIAGKMDLKSSSKLKNGLTFRKEDMLQRQLHLEGMLCWKTTSGRLKDILAILLTDVLLLLQEKDQKYVFASVDSKPPVISLQKLIVREVANEEKAMFLISASLQGPEMYEIYTSSKEDRNAWMAHIQRAVESCPDEEEGPFSLPEEERKVVEARATRLRDFQERLSMKDQLIAQSLLEKQQIYLEMAEMGGLEDLPQPRGLFRGGDPSETLQGELILKSAMSEIEGIQSLICRQLGSANGQAEDGGSSTGPPRRAETFAGYDCTNSPTKNGSFKKKVSSTDPRPRDWRGPPNSPDLKLSDSDIPGSSEESPQVVEAPGTESDPRLPTVLESELVQRIQTLSQLLLNLQAVIAHQDSYVETQRAAIQEREKQFRLQSTRGNLLLEQERQRNFEKQREERAALEKLQSQLRHEQQRWERERQWQHQELERAGARLQEREGEARQLRERLEQERAELERQRQAYQHDLERLREAQRAVERERERLELLRRLKKQNTAPGALPPDTLAEAQPPSHPPSFNGEGLEGPRVSMLPSGVGPEYAERPEVARRDSAPTENRLAKSDVPIQLLSATNQFQRQAAVQQQIPTKLAASTKGGKDKGGKSRGSQRWESSASFDLKQQLLLNKLMGKDESTSRNRRSLSPILPGRHSPAPPPDPGFPAPSPPPADSPSEGFSLKAGGTALLPGPPAPSPLP", "length": 1089 }, "evidence": [ { "id": "A0A8V1AFK2", "url": "https://omabrowser.org/oma/group/A0A8V1AFK2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "E1B9G8-1", "protein_name": "Rho/Rac guanine nucleotide exchange factor 18", "gene_name": "ARHGEF18", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MEDEQEDGIPGLLGGSESSEDLSLDLGALQGSEYLQDLGLEVLSHSQPGGARDSGPPSEEARGETPRGETPLSSAARSQGLARRRSWERSRSCSESRQRLSIESSAVNEGPFLPRTLASLALNLPGEGLQAWTQGCLPGGGTPAEQPSKECDSPEKRVRSRSVPVSFDEISSLEIFPALEVPPPAVQGLDPPVLECMEKDHVEPNHVLIVQQVLEELRQYHGARQRARLSVCPGGAASNLTWFEFLSESEDSMGKTERSDRGTKVKRSLSSLRNRVTRQKEKGKTPVHQKDKGQDARERKECINGHQLARGTFSGHSSCPMCGKPFLSSASLKEHPRATLLSDGSPRPTRNVGMTVSQKGGPQPAPSPAGTGTRLGPLTGEMDETDTLFPKLKQVADDSLFLTSSSTEPIFIEDPYTASLRGEVEADTHEFEAESWSLSVDPEYVKKQKREVVKRQDVLYELMQTEAHHVRTLKIMLKVYSRALREELQFSPKAVSRLFPGADDLLEVHSHFLCRLKERRLESLEEGSAHNYIIRKIGDLLLQQFSGENGERMKEKYSVFCSGHNDAVSHYKLLLQQNKKFQNLIKRIGNFSIVRRLGVQECILLVTQRITKYPVLVERIIQNTEAGSEDHRDLTQALNLIKDIISQVDARVSECEKGQRLREIAGKMDLKSSSKLKNGLTFRKEDMLQRQLHLEGTLCWKTTSGRLKDVLAVLLTDVLLLLQEKDQKYVFASVDSKRPVISLQKLIVREVANEEKAMFLISASLHGPEMYEIYTSSKEDRNTWMAHIRRAVESCPDEEEGPFSEAEEEKKVVETRAVRLRDFQERLNRKDQQIAQSLSEKQQIYLEMAEMSGLEDLALSRLLFRGGDPPENLQGELILKSAMSEIEDIQSFICRRLGNAYCQAEDGGSAGSPGKDGSLQKNMCSSDLSPRDWQGLVSSLDSRPGDTQGAPEEASKVAESPGADPGPHPPAVLELELVQRIQTLSQLLLSLQVVIAQQDSYVEIQKAAIQEREKQFRLQSTRGNLLLEQERQRNFEKQREELAGVQKLQGQLRLEQQRWEREREQQRRELDQASARLQQRESELLRLQERLNQEREELERQRQAYQHDLERLREAQRAVERERERLEVLRRLKKQNTAPGALPPEALAETQPLSHTPSFNGNGLDGSMTLTKAPGPRPTSLVSSAGSEYAERPEVARRDSAPAKSEVPIQLLSATNQIQRQAAVQQQIPTKLAASTKGGKDKGGKNRGSQRWDSSASFDLRQPLLLNKLMGKEENTSRNRRSLSPVLPSSTPHQDPSLPAPTPGPADVPTESLPLKTWGPSFPPGAPSSTPVNKEETGKEDVIFF", "length": 1345 }, "evidence": [ { "id": "A0A8V1AFK2", "url": "https://omabrowser.org/oma/group/A0A8V1AFK2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFK2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFK2" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFK2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFK2" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFK2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFK2" } ], "pmid": "" }, { "name": "apical part of cell", "id": "GO:0045177", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045177", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFK2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFK2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFK2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFK2" } ], "pmid": "" }, { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFK2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFK2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "small GTPase-mediated signal transduction", "id": "GO:0007264", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007264", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFK2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFK2" } ], "pmid": "" }, { "name": "protein localization to cell-cell junction", "id": "GO:0150105", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0150105", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFK2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFK2" } ], "pmid": "" }, { "name": "negative regulation of stress fiber assembly", "id": "GO:0051497", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051497", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFK2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFK2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1101, "end_pos": 1103, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1133, "end_pos": 1135, "annotation": "n_glycosylation_sequon" }, { "start_pos": 116, "end_pos": 118, "annotation": "n_glycosylation_sequon" }, { "start_pos": 322, "end_pos": 324, "annotation": "n_glycosylation_sequon" }, { "start_pos": 381, "end_pos": 383, "annotation": "n_glycosylation_sequon" }, { "start_pos": 477, "end_pos": 479, "annotation": "n_glycosylation_sequon" }, { "start_pos": 791, "end_pos": 793, "annotation": "n_glycosylation_sequon" }, { "start_pos": 7, "end_pos": 9, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AFK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFK2" }, { "id": "PS50010", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50010" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DH", "eco_id": "ECO_0000259", "start_pos": 655, "end_pos": 852, "start_aa": "Lys", "end_aa": "Ile", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1AFK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFK2" }, { "id": "PS50003", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50003" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PH", "eco_id": "ECO_0000259", "start_pos": 892, "end_pos": 994, "start_aa": "Arg", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1AFK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFK2" }, { "id": "PS50081", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50081" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Phorbol-ester/DAG-type", "eco_id": "ECO_0000259", "start_pos": 454, "end_pos": 501, "start_aa": "Arg", "end_aa": "Cys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1101, "end_pos": 1103 }, { "start_pos": 1133, "end_pos": 1135 }, { "start_pos": 116, "end_pos": 118 }, { "start_pos": 322, "end_pos": 324 }, { "start_pos": 381, "end_pos": 383 }, { "start_pos": 477, "end_pos": 479 }, { "start_pos": 791, "end_pos": 793 }, { "start_pos": 7, "end_pos": 9 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AFN1-1", "uniprot_ac": "A0A8V1AFN1", "uniprot_id": "A0A8V1AFN1_CHICK", "mass": { "chemical_mass": 79785.0, "monoisotopic_mass": 79785.0 }, "refseq": { "ac": "XP_418032", "name": "LEM domain-containing protein 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418032" }, "gene_names": [ { "name": "LEMD2", "type": "recommended", "evidence": [ { "id": "A0A8V1AFN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFN1" } ] }, { "name": "LEMD2", "type": "synonym", "evidence": [ { "id": "XP_418032", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418032" } ] } ], "protein_names": [ { "name": "LEM domain-containing protein 2", "type": "recommended", "evidence": [ { "id": "A0A8V1AFN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFN1/entry#names_and_taxonomy" } ] }, { "name": "LEM domain-containing protein 2", "type": "synonym", "evidence": [ { "id": "XP_418032", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418032" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052557.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_418032.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_418032", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418032" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFN1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFN1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LEMD2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFN1", "locus": { "chromosome": "26", "start_pos": 4638202, "end_pos": 4625232, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027260", "url": "https://www.ensembl.org/id/ENSGALG00010027260" } ] } } ], "crossref": [ { "id": "A0A8V1AFN1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AFN1", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd12941", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12941", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "419907", "url": "https://www.ncbi.nlm.nih.gov/gene/419907", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003887", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003887", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011015", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011015", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018996", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018996", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041885", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041885", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052277", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052277", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:419907", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419907", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VAPSTHW", "url": "https://omabrowser.org/oma/group/VAPSTHW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A394", "url": "https://www.orthodb.org/?gene=A0A8V1A394", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AFN1", "url": "https://www.orthodb.org/?gene=A0A8V1AFN1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13428", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13428", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13428:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13428:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03020", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03020", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF09402", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09402", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_418032", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418032", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1A394", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A394", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A394-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A394-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFN1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFN1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFN1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFN1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAELTDAELRKELLALGYRPGPITETTRKVYIKKLSCLRAEVAAAKRRGRGAPPSPGRSSGRPQQASPSRPRLGFSLSPGRAARDREEEDEDEMEEDEMEEDEEEERGRAPVSRWEAAEGGRLSWGDPRGSPPGRSGGLGGRNEGGMSRDGLRGLSTPSSWSSSLERSGGLRAETGPSRDDGFWYSSSFEWNTSTEGSEGLSSGLRPSLDGSGGPSVSHWKTSIDRGEGLSARAGIGTSMDGVGGLSSMSSWGTSAGKSGRLSSTPFSSDESGGLTARSHWDSSVGRTAGQNSPAQWETAGERKAERKGLFSNSWWGRESKVAPSTHWGTTAGRSGLSYPFERGEENLASSIRREADREPKSSSWGEGLTRRLPWRAVSDTRLASGSRWDASAAVVTPRTQLLRSAPRQQVEGKRKGLEYYLSQFLCFASLVLLLIFLGILMVKMIGSGWLDQTEENFNLLPVDCDKRTDDFCRAKQKDVVMNMLHELYNYLSIQAGNFECGNPENLKSKCIWVSEARDYVVNITGGSPQKFEAALSWILNSNKDLGIWLKGKDLSEPVTRVEEVVCLESAHPQMGLSCRFRRAVITAVMNLFLFFWCLVTLWGILIFLRYRWRKMEEEEQAMYDMVKKIIAVVQDHYKEWERNLERYPYVGILHVRDSLIPPQSRKKMKRVWNRAVEFLASNESRIQTESHRVAGEDMLVWRWTQPSYVSDSEH", "length": 715, "header": "tr|A0A8V1AFN1-1|A0A8V1AFN1_CHICK Isoform 1 of LEM domain-containing protein 2 OS=Gallus gallus OX=9031 GN=LEMD2 PE=1 SV=1 CANONICAL=A0A8V1AFN1-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A394-1", "url": 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"chromosome": "26", "start_pos": 4636195, "end_pos": 4625362, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066087.1", "url": "https://www.ensembl.org/id/ENSGALT00010066087.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040353.1", "url": "https://www.ensembl.org/id/ENSGALP00010040353.1" } ] } }, { "isoform_ac": "A0A8V1AFN1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFN1/entry#A0A8V1AFN1-1", "sequence": { "sequence": "MAELTDAELRKELLALGYRPGPITETTRKVYIKKLSCLRAEVAAAKRRGRGAPPSPGRSSGRPQQASPSRPRLGFSLSPGRAARDREEEDEDEMEEDEMEEDEEEERGRAPVSRWEAAEGGRLSWGDPRGSPPGRSGGLGGRNEGGMSRDGLRGLSTPSSWSSSLERSGGLRAETGPSRDDGFWYSSSFEWNTSTEGSEGLSSGLRPSLDGSGGPSVSHWKTSIDRGEGLSARAGIGTSMDGVGGLSSMSSWGTSAGKSGRLSSTPFSSDESGGLTARSHWDSSVGRTAGQNSPAQWETAGERKAERKGLFSNSWWGRESKVAPSTHWGTTAGRSGLSYPFERGEENLASSIRREADREPKSSSWGEGLTRRLPWRAVSDTRLASGSRWDASAAVVTPRTQLLRSAPRQQVEGKRKGLEYYLSQFLCFASLVLLLIFLGILMVKMIGSGWLDQTEENFNLLPVDCDKRTDDFCRAKQKDVVMNMLHELYNYLSIQAGNFECGNPENLKSKCIWVSEARDYVVNITGGSPQKFEAALSWILNSNKDLGIWLKGKDLSEPVTRVEEVVCLESAHPQMGLSCRFRRAVITAVMNLFLFFWCLVTLWGILIFLRYRWRKMEEEEQAMYDMVKKIIAVVQDHYKEWERNLERYPYVGILHVRDSLIPPQSRKKMKRVWNRAVEFLASNESRIQTESHRVAGEDMLVWRWTQPSYVSDSEH", "length": 715, "header": "tr|A0A8V1AFN1-1|A0A8V1AFN1_CHICK Isoform 1 of LEM domain-containing protein 2 OS=Gallus gallus OX=9031 GN=LEMD2 PE=1 SV=1 CANONICAL=A0A8V1AFN1-1" }, "locus": { "chromosome": "26", "start_pos": 4636195, "end_pos": 4625362, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066088.1", "url": "https://www.ensembl.org/id/ENSGALT00010066088.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040354.1", "url": "https://www.ensembl.org/id/ENSGALP00010040354.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:419907", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419907", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "spindle", "id": "GO:0005819", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005819", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFN1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFN1" } ], "pmid": "" }, { "name": "nuclear inner membrane", "id": "GO:0005637", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005637", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFN1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFN1" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFN1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFN1" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFN1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFN1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "skeletal muscle cell differentiation", "id": "GO:0035914", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035914", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFN1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFN1" } ], "pmid": "" }, { "name": "negative regulation of BMP signaling pathway", "id": "GO:0030514", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030514", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFN1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFN1" } ], "pmid": "" }, { "name": "negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction", "id": "GO:0051898", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051898", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFN1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFN1" } ], "pmid": "" }, { "name": "nuclear envelope organization", "id": "GO:0006998", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006998", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFN1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFN1" } ], "pmid": "" }, { "name": "neurogenesis", "id": "GO:0022008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022008", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFN1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFN1" } ], "pmid": "" }, { "name": "heart formation", "id": "GO:0060914", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060914", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFN1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFN1" } ], "pmid": "" }, { "name": "protein localization to chromatin", "id": "GO:0071168", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071168", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFN1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFN1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "chromatin DNA binding", "id": "GO:0031490", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031490", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFN1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFN1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 192, "end_pos": 194, "annotation": "n_glycosylation_sequon" }, { "start_pos": 523, "end_pos": 525, "annotation": "n_glycosylation_sequon" }, { "start_pos": 683, "end_pos": 685, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AFN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFN1" }, { "id": "PS50954", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50954" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "LEM", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 42, "start_aa": "Met", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 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{ "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AFN9-1", "uniprot_ac": "A0A8V1AFN9", "uniprot_id": "A0A8V1AFN9_CHICK", "mass": { "chemical_mass": 76016.0, "monoisotopic_mass": 76016.0 }, "refseq": {}, "gene_names": [ { "name": "LOC420374", "type": "recommended", "evidence": [ { "id": "A0A8V1AFN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFN9" } ] } ], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "A0A8V1AFN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFN9/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFN9", "url": 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"categories": [ "Protein Classification" ] }, { "id": "IPR017907", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017907", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043136", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043136", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050143", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050143", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:420374", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420374", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MAMGKIW", "url": "https://omabrowser.org/oma/group/MAMGKIW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A3A9", "url": "https://www.orthodb.org/?gene=A0A8V1A3A9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AAV3", "url": "https://www.orthodb.org/?gene=A0A8V1AAV3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AFN9", "url": "https://www.orthodb.org/?gene=A0A8V1AFN9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24103", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24103", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00622", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00622", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00643", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00643", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13765", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13765", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14634", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14634", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-3232142", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3232142", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-8948751", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8948751", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1A3A9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3A9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A3A9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3A9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AAV3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAV3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AAV3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAV3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFN9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFN9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFN9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFN9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MARALQALGEQLQAEATCPLCLELFSRPVLTACGHSLCSPCAQVLLGSPPRPAACPQCRATVEPGSLRPNFPLGAVAELAAALEEAAGEEAKRPRCSEHGEALELFCQSCFQVLCPRCREEGPHCGHRTRPAEEAAKILRETLQSNLVFLEKEKEEFNPKGESRINMLMVCAHLCPAPPARSSTLLGVQPFSSFILISFSRTTLLFSLSHPVHPISPSIRPSHISFHTSIPYLLPYVHPISPSIRPSHISFHTSIPYLLPYVHPISPSIRPSHISFYMSVLYLLPYVHPVSPSKCPPHISFLMPIPYAFHTSLPYIFPYIHPVYFSIYPSPTSSHLSIPYNLLYIHSFSPPRLCLLAMIPIPSPQQTGCSGPGVSQGTVASEQQKLRTAFEQLQQFLREQEGALLAQLDGAHARLSEQHREYTCRVSERGTLLEELVEEIQKKRDQPAVEFLMDVAGILDRCVEAKVPVPDPVSSELQRTVSNLCKTSERVLAVLGDFRVDLLSKMDTERVKVLLDLETASRYLTISSDCRTLQIAEGWQNLSDTPKRFTGSASVLGSQGFTAGRHYWELEVGDGNNWAVGVALESVQRKESLMMAMEKIWALRMDWDRSYTALTMPPAPLSLQEEPRRIRVHLDYEAGQVTFYNTDNMQQLLQFKVSFSEKVFPYFWLGLPGTYIKLRS", "length": 680, "header": "tr|A0A8V1AFN9-1|A0A8V1AFN9_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN=LOC420374 PE=4 SV=1 CANONICAL=A0A8V1AFN9-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A3A9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFN9/entry#A0A8V1A3A9-1", "sequence": { "sequence": "MARALQALGEQLQAEATCPLCLELFSRPVLTACGHSLCSPCAQVLLGSPPRPAACPQCRATVEPGSLRPNFPLGAVAELAAALEEAAGEEAKRPRCSEHGEALELFCQSCFQVLCPRCREEGPHCGHRTRPAEEAAKILRETLQSNLVFLEKEKEEFNPKGESRINMLMGTVASEQQKLRTAFEQLQQFLREQEGALLAQLDGAHARLSEQHREYTCRVSERGTLLEELVEEIQKKRDQPAVEFLMDVAGILDRCVEAKVPVPDPVSSELQRTVSNLCKTSERVLAVLGDFRVDLLSKMDTERVKVLLDLETASRYLTISSDCRTLQIAEGWQNLSDTPKRFTGSASVLGSQGFTAGRHYWELEVGDGNNWAVGVALESVQRKESLMMAMEKIWALRMDWDRSYTALTMPPAPLSLQEEPRRIRVHLDYEAGQVTFYNTDNMQQLLQFKVSFSEKVFPYFWLGLPGTYIKLRS", "length": 473, "header": "tr|A0A8V1A3A9-1|A0A8V1AFN9_CHICK Computationally mapped isoform of Uncharacterized protein OS=Gallus gallus OX=9031 GN=LOC420374 PE=4 SV=1 CANONICAL=A0A8V1AFN9-1" }, "locus": { "chromosome": "2", "start_pos": 618367, "end_pos": 612186, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066102.1", "url": "https://www.ensembl.org/id/ENSGALT00010066102.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040368.1", "url": "https://www.ensembl.org/id/ENSGALP00010040368.1" } ] } }, { "isoform_ac": "A0A8V1AAV3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFN9/entry#A0A8V1AAV3-1", "sequence": { "sequence": "LCCALVKVLLDLETASRYLTISSDCRTLQIAEGWQNLSDTPKRFTGSASVLGSQGFTAGRHYWELEVGDGNNWAVGVALESVQRKESLMMAMEKIWALRMDWDRSYTALTMPPAPLSLQEEPRRIRVHLDYEAGQVTFYNTDNMQQLLQFKVSFSEKVFPYFWLGLPGTYIKLRS", "length": 175, "header": "tr|A0A8V1AAV3-1|A0A8V1AFN9_CHICK Computationally mapped isoform of Uncharacterized protein OS=Gallus gallus OX=9031 GN=LOC420374 PE=4 SV=1 CANONICAL=A0A8V1AFN9-1" }, "locus": { "chromosome": "2", "start_pos": 618367, "end_pos": 617843, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066101.1", "url": "https://www.ensembl.org/id/ENSGALT00010066101.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040367.1", "url": "https://www.ensembl.org/id/ENSGALP00010040367.1" } ] } }, { "isoform_ac": "A0A8V1AFN9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFN9/entry#A0A8V1AFN9-1", "sequence": { "sequence": "MARALQALGEQLQAEATCPLCLELFSRPVLTACGHSLCSPCAQVLLGSPPRPAACPQCRATVEPGSLRPNFPLGAVAELAAALEEAAGEEAKRPRCSEHGEALELFCQSCFQVLCPRCREEGPHCGHRTRPAEEAAKILRETLQSNLVFLEKEKEEFNPKGESRINMLMVCAHLCPAPPARSSTLLGVQPFSSFILISFSRTTLLFSLSHPVHPISPSIRPSHISFHTSIPYLLPYVHPISPSIRPSHISFHTSIPYLLPYVHPISPSIRPSHISFYMSVLYLLPYVHPVSPSKCPPHISFLMPIPYAFHTSLPYIFPYIHPVYFSIYPSPTSSHLSIPYNLLYIHSFSPPRLCLLAMIPIPSPQQTGCSGPGVSQGTVASEQQKLRTAFEQLQQFLREQEGALLAQLDGAHARLSEQHREYTCRVSERGTLLEELVEEIQKKRDQPAVEFLMDVAGILDRCVEAKVPVPDPVSSELQRTVSNLCKTSERVLAVLGDFRVDLLSKMDTERVKVLLDLETASRYLTISSDCRTLQIAEGWQNLSDTPKRFTGSASVLGSQGFTAGRHYWELEVGDGNNWAVGVALESVQRKESLMMAMEKIWALRMDWDRSYTALTMPPAPLSLQEEPRRIRVHLDYEAGQVTFYNTDNMQQLLQFKVSFSEKVFPYFWLGLPGTYIKLRS", "length": 680, "header": "tr|A0A8V1AFN9-1|A0A8V1AFN9_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN=LOC420374 PE=4 SV=1 CANONICAL=A0A8V1AFN9-1" }, "locus": { "chromosome": "2", "start_pos": 618367, "end_pos": 612186, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066098.1", "url": "https://www.ensembl.org/id/ENSGALT00010066098.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040364.1", "url": "https://www.ensembl.org/id/ENSGALP00010040364.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 332, "start_aa": "Thr", "end_pos": 332, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr332", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:420374", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420374", "resource": "KEGG Pathway" }, { "id": "R-GGA-3232142", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3232142", "resource": "Reactome", "description": "SUMOylation of ubiquitinylation proteins" }, { "id": "R-GGA-8948751", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8948751", "resource": "Reactome", "description": "Regulation of PTEN stability and activity" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFN9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFN9" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFN9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFN9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFN9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFN9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFN9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFN9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 541, "end_pos": 543, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AFN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFN9" }, { "id": "PS50119", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50119" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "B box-type", "eco_id": "ECO_0000259", "start_pos": 91, "end_pos": 132, "start_aa": "Ala", "end_aa": "Ala", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1AFN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFN9" }, { "id": "PS50188", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50188" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "B30.2/SPRY", "eco_id": "ECO_0000259", "start_pos": 493, "end_pos": 680, "start_aa": "Ala", "end_aa": "Ser", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1AFN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFN9" }, { "id": "PS50089", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50089" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RING-type", "eco_id": "ECO_0000259", "start_pos": 18, "end_pos": 59, "start_aa": "Cys", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 332 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 541, "end_pos": 543 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AFR7-1", "uniprot_ac": "A0A8V1AFR7", "uniprot_id": "A0A8V1AFR7_CHICK", "mass": { "chemical_mass": 206389.0, "monoisotopic_mass": 206389.0 }, "refseq": { "ac": "XP_046760671", "name": "C3 and PZP-like alpha-2-macroglobulin domain-containing protein 8 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046760671" }, "gene_names": [ { "name": "CPAMD8", "type": "recommended", "evidence": [ { "id": "A0A8V1AFR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFR7" } ] }, { "name": "CPAMD8", "type": "synonym", "evidence": [ { "id": "XP_046760671", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046760671" } ] } ], "protein_names": [ { "name": "C3 and PZP like alpha-2-macroglobulin domain containing 8", "type": "synonym", "evidence": [ { "id": "A0A8V1AFR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFR7/entry#names_and_taxonomy" } ] }, { "name": "C3 and PZP-like alpha-2-macroglobulin domain-containing protein 8 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_046760671", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046760671" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052559.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_046760671", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046760671" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFR7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFR7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CPAMD8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFR7", "locus": { "chromosome": "28", "start_pos": 4700661, "end_pos": 4659947, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027275", "url": "https://www.ensembl.org/id/ENSGALG00010027275" } ] } } ], "crossref": [ { "id": "cd00104", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00104", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd02897", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02897", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "420138", "url": "https://www.ncbi.nlm.nih.gov/gene/420138", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002350", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002350", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002890", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002890", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008930", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008930", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009048", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009048", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011625", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011625", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011626", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011626", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014756", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014756", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019742", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019742", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022041", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022041", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036058", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036058", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036595", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036595", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040839", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040839", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041555", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041555", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041813", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041813", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047565", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047565", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050473", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050473", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "CGCARDC", "url": "https://omabrowser.org/oma/group/CGCARDC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A3E3", "url": "https://www.orthodb.org/?gene=A0A8V1A3E3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AAY4", "url": "https://www.orthodb.org/?gene=A0A8V1AAY4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AFR7", "url": "https://www.orthodb.org/?gene=A0A8V1AFR7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11412", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11412", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11412:SF139", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11412:SF139", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00207", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00207", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01835", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01835", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07648", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07648", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07677", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07677", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07678", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07678", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07703", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07703", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12248", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12248", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17789", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17789", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17791", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17791", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_046760671", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046760671", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1A3E3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3E3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A3E3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3E3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AAY4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAY4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AAY4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAY4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFR7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFR7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFR7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFR7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MHRAERRCAWGVLLTLCGLSAAQPRGRQGYLIAAPSVFRSGVEEAVSVTIFNAVKETTVQIQLVVKGETVSRGHGTVLDKGTIKLKVPSGLRGQGHLKVWGNRHVTEEGYIFHNYTTVTIDSKGSSVFIQTDKPVYKPKQKVLINLFTVTSDLRPFNDRIEAYVVDPRGSRMIEWNNLKPFCCGMVNMSFPLSDQPVFGEWLIFAEMQGHTYNKSFEVQKYVLPKFELLIDPPRYIRDLTACEKGTVHARYTFGKPVTGKLIVNMTINGVGYYRHEVGHPVLKTTQIDGSAVFDVCVKEMMPADVPEHFRGTVNIWATVVSSDGSKQVTFDDSTPVQKQLIDIKYSKDTRKQFKPGLPYKGKVEVTYPDGSPADRVTVRIKAELTPKDNVYTSELVSRNGLVEFEIPSIPTAAQYVWLETKVTAIDGRPSGDQYLPNYLSISSWYSPSKCHIQLQAPDKPFQVGEEAWIAVKSTCPCNFTLHYEVASRGNIVLSGLQPSNITQQRSKRATIPFEKSTDVTHFPGAAPTDIPAAEVEVCMTFLRFSVSHNMAPLGRLLVYYVRENGEGVTDSLQFSVKSTFENQVAVTLSANETRPGDVVNIKVRAAKSSCVCIATVDKSVYLLKTGFQLTASQVFKELAEYDVSDAFGAPKEEGHFWWPGMSSRRRRRSSVFPWHWDVTKDARFAFTETGLVVMTDTVSLNHRQNGGMYTDEAVPAFQPHTGTLVATMRSKMAQSRAEKRKRTFFPETWIWHCLNVSNTSGEAELHVEVPDSITTWITEAVGLSEEKGLGIASQTELKTFKPFFIDFTLPYHVIRGEQTKIPLTVYNYLTVCVEVHVKISVPKGIKFVGHPGKHHLTRKKCVAPGEAKPTSIVLSFSELGLSNITAKAFAYGGTNCCQNGMQALKNGKHSEDNYVDKRTPVGVDYVRSSVVIEPEGLSREYTYSVFFCPNEKIHISTPNKYEYQYMQKPAQMTHFDIAVKAHNDAHVALSSGPHDMAEMTEIVIGGHQNTKTWISISKMGEPVVSRDTAGILSWDEFRSFWISWKNGIIQVGHGTRVLNESIIVEWTVPKQFEVKYIGFSTGWGSIGEFKIWRKEETDENHNEAFTLGVPHNIIPGSERATASIIGDVMGPTLNNLDNLLRLPFGCGEQNMIHFAPNVFVLKYLQKTKQLSQEVESEATDYLVQGYQRQLTYKRQDGSYSAFGERDSSGSMWLTAFVLKSFAQSRGFIFIDPKELTAAKEWIIQHQKEDGSFPAMGRILNKDIQGGIHGKISLTAYVVASLLETGVTSEEERSAVDKAKHFLESNLHSAEDPYTTALTAYALTLLHSPAAAVALRKMNSMAITQDGFTHWSLTGSLVTDEDTFMGFNDGLSQSVVSAEVEMTSYALLTYTLLGDVASALPVVKWLSQQRNALGGFSSTQDTCVALQALAEYAILSYVGGVNLTISLASTNLDYQETFELNKMNKKVLQTAVIPSIPTGLFVSAKGEGCCLMQIDVTYNVPDPIAKPAFQLLVNLKEPKSEQHLQAPVLLRSLSPDENRSETLHRERAVVDDDDPAADRDHQEYKVILETCTRWLHSGSSNMAVLEVPLFSGFRADIESLEQLLMNKQIGLKRYEVDGRKVLFYFDEIPSQCMTCVKFQAFREYIVGKTAPVPIKVYDYYEPAFEATRFYNVSENSPLARELCDGPTCNEVESSASQWAGFSHSGPCNNIFGCLEDEYFEQCMCSRDCGYDGDPVCGSDGQIYQNHCQMEVASCRNNTRIEQIPMSQCSNSKNLPEERETNSHTAEQPSVQQPPAAEEGPPLQLDLSYYSYEYDPDPYASEADVFEMVAELTTVSTFREADTIQEVVTTIE", "length": 1850, "header": "tr|A0A8V1AFR7-1|A0A8V1AFR7_CHICK Isoform 1 of C3 and PZP like alpha-2-macroglobulin domain containing 8 OS=Gallus gallus OX=9031 GN=CPAMD8 PE=3 SV=1 CANONICAL=A0A8V1AFR7-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A3E3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFR7/entry#A0A8V1A3E3-1", "sequence": { "sequence": "MWIHARSCIFLLQSSNDRGYLIAAPSVFRSGVEEAVSVTIFNAVKETTVQIQLVVKGETVSRGHGTVLDKGTIKLKVPSGLRGQGHLKVWGNRHVTEEGYIFHNYTTVTIDSKGSSVFIQTDKPVYKPKQKVLINLFTVTSDLRPFNDRIEAYVVDPRGSRMIEWNNLKPFCCGMVNMSFPLSDQPVFGEWLIFAEMQGHTYNKSFEVQKYVLPKFELLIDPPRYIRDLTACEKGTVHARYTFGKPVTGKLIVNMTINGVGYYRHEVGHPVLKTTQIDGSAVFDVCVKEMMPADVPEHFRGTVNIWATVVSSDGSKQVTFDDSTPVQKQLIDIKYSKDTRKQFKPGLPYKGKVEVTYPDGSPADRVTVRIKAELTPKDNVYTSELVSRNGLVEFEIPSIPTAAQYVWLETKVTAIDGRPSGDQYLPNYLSISSWYSPSKCHIQLQAPDKPFQVGEEAWIAVKSTCPCNFTLHYEVASRGNIVLSGLQPSNITQQRSKRATIPFEKSTDVTHFPGAAPTDIPAAEVEVCMTFLRFSVSHNMAPLGRLLVYYVRENGEGVTDSLQFSVKSTFENQVAVTLSANETRPGDVVNIKVRAAKSSCVCIATVDKSVYLLKTGFQLTASQVFKELAEYDVSDAFGAPKEEGHFWWPGMSSRRRRRSSVFPWHWDVTKDARFAFTETGLVVMTDTVSLNHRQNGGMYTDEAVPAFQPHTGTLVATMRSKMAQSRAEKRKRTFFPETWIWHCLNVSNTSGEAELHVEVPDSITTWITEAVGLSEEKGLGIASQTELKTFKPFFIDFTLPYHVIRGEQTKIPLTVYNYLTVCVEVHVKISVPKGIKFVGHPGKHHLTRKKCVAPGEAKPTSIVLSFSELGLSNITAKAFAYGGTNCCQNGMQALKNGKHSEDNYVDKRTPVGVDYVRSSVVIEPEGLSREYTYSVFFCPNEKIHISTPNKYEYQYMQKPAQMTHFDIAVKAHNDAHVALSSGPHDMAEMTEIVIGGHQNTKTWISISKMGEPVVSRDTAGILSWDEFRSFWISWKNGIIQVGHGTRVLNESIIVEWTVPKQFEVKYIGFSTGWGSIGEFKIWRKEETDENHNEAFTLGVPHNIIPGSERATASIIGDVMGPTLNNLDNLLRLPFGCGEQNMIHFAPNVFVLKYLQKTKQLSQEVESEATDYLVQGYQRQLTYKRQDGSYSAFGERDSSGSMWLTAFVLKSFAQSRGFIFIDPKELTAAKEWIIQHQKEDGSFPAMGRILNKDIQGGIHGKISLTAYVVASLLETGVTSEEERSAVDKAKHFLESNLHSAEDPYTTALTAYALTLLHSPAAAVALRKMNSMAITQDGFTHWSLTGSLVTDEDTFMGFNDGLSQSVVSAEVEMTSYALLTYTLLGDVASALPVVKWLSQQRNALGGFSSTQDTCVALQALAEYAILSYVGGVNLTISLASTNLDYQETFELNKMNKKVLQTAVIPSIPTGLFVSAKGEGCCLMQIDVTYNVPDPIAKPAFQLLVNLKEPKSEQHLQAPVLLRSLSPDENRSETLHRERAVVDDDDPAADRDHQEYKVILETCTRWLHSGSSNMAVLEVPLFSGFRADIESLEQLLMNKQIGLKRYEVDGRKVLFYFDEIPSQCMTCVKFQAFREYIVGKTAPVPIKVYDYYEPAFEATRFYNVSENSPLARELCDGPTCNEVESSASQWAGFSHSGPCNNIFGCLEDEYFEQCMCSRDCGYDGDPVCGSDGQIYQNHCQMEVASCRNNTRIEQIPMSQCSNSKNLPEERETNSHTAEQPSVQQPPAAEEGPPLQLDLSYYSYEYDPDPYASEADVFEMVAELTTVSTFREADTIQEVVTTIE", "length": 1840, "header": "tr|A0A8V1A3E3-1|A0A8V1AFR7_CHICK Computationally mapped isoform of C3 and PZP like alpha-2-macroglobulin domain containing 8 OS=Gallus gallus OX=9031 GN=CPAMD8 PE=3 SV=1 CANONICAL=A0A8V1AFR7-1" }, "locus": { "chromosome": "28", "start_pos": 4699364, "end_pos": 4660518, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066132.1", "url": "https://www.ensembl.org/id/ENSGALT00010066132.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040398.1", "url": "https://www.ensembl.org/id/ENSGALP00010040398.1" } ] } }, { "isoform_ac": "A0A8V1AAY4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFR7/entry#A0A8V1AAY4-1", "sequence": { "sequence": "MRCAFSKDQRAEAVLTAMLVLTRGGYLIAAPSVFRSGVEEAVSVTIFNAVKETTVQIQLVVKGETVSRGHGTVLDKGTIKLKVPSGLRGQGHLKVWGNRHVTEEGYIFHNYTTVTIDSKGSSVFIQTDKPVYKPKQKVLINLFTVTSDLRPFNDRIEAYVVDPRGSRMIEWNNLKPFCCGMVNMSFPLSDQPVFGEWLIFAEMQGHTYNKSFEVQKYVLPKFELLIDPPRYIRDLTACEKGTVHARYTFGKPVTGKLIVNMTINGVGYYRHEVGHPVLKTTQIDGSAVFDVCVKEMMPADVPEHFRGTVNIWATVVSSDGSKQVTFDDSTPVQKQLIDIKYSKDTRKQFKPGLPYKGKVEVTYPDGSPADRVTVRIKAELTPKDNVYTSELVSRNGLVEFEIPSIPTAAQYVWLETKVTAIDGRPSGDQYLPNYLSISSWYSPSKCHIQLQAPDKPFQVGEEAWIAVKSTCPCNFTLHYEVASRGNIVLSGLQPSNITQQRSKRATIPFEKSTDVTHFPGAAPTDIPAAEVEVCMTFLRFSVSHNMAPLGRLLVYYVRENGEGVTDSLQFSVKSTFENQVAVTLSANETRPGDVVNIKVRAAKSSCVCIATVDKSVYLLKTGFQLTASQVFKELAEYDVSDAFGAPKEEGHFWWPGMSSRRRRRSSVFPWHWDVTKDARFAFTETGLVVMTDTVSLNHRQNGGMYTDEAVPAFQPHTGTLVATMRSKMAQRAEKRKRTFFPETWIWHCLNVSNTSGEAELHVEVPDSITTWITEAVGLSEEKGLGIASQTELKTFKPFFIDFTLPYHVIRGEQTKIPLTVYNYLTVCVEVHVKISVPKGIKFVGHPGKHHLTRKKCVAPGEAKPTSIVLSFSELGLSNITAKAFAYGGTNCCQNGMQALKNGKHSEDNYVDKRTPVGVDYVRSSVVIEPEGLSREYTYSVFFCPNEKIHISTPNKYEYQYMQKPAQMTHFDIAVKAHNDAHVALSSGPHDMAEMTEIVIGGHQNTKTWISISKMGEPVVSRDTAGILSWDEFRSFWISWKNGIIQVGHGTRVLNESIIVEWTVPKQFEVKYIGFSTGWGSIGEFKIWRKEETDENHNEAFTLGVPHNIIPGSERATASIIGDVMGPTLNNLDNLLRLPFGCGEQNMIHFAPNVFVLKYLQKTKQLSQEVESEATDYLVQGYQRQLTYKRQDGSYSAFGERDSSGSMWLTAFVLKSFAQSRGFIFIDPKELTAAKEWIIQHQKEDGSFPAMGRILNKDIQGGIHGKISLTAYVVASLLETGVTSEEERSAVDKAKHFLESNLHSAEDPYTTALTAYALTLLHSPAAAVALRKMNSMAITQDGFTHWSLTGSLVTDEDTFMGFNDGLSQSVVSAEVEMTSYALLTYTLLGDVASALPVVKWLSQQRNALGGFSSTQDTCVALQALAEYAILSYVGGVNLTISLASTNLDYQETFELNKMNKKVLQTAVIPSIPTGLFVSAKGEGCCLMQIDVTYNVPDPIAKPAFQLLVNLKEPKSEQHLQAPVLLRSLSPDENRSETLHRERAVVDDDDPAADRDHQEYKVILETCTRWLHSGSSNMAVLEVPLFSGFRADIESLEQLLMNKQIGLKRYEVDGRKVLFYFDEIPSQCMTCVKFQAFREYIVGKTAPVPIKVYDYYEPAFEATRFYNVSENSPLARELCDGPTCNEVESSASQWAGFSHSGPCNNIFGCLEDEYFEQCMCSRDCGYDGDPVCGSDGQIYQNHCQMEVASCRNNTRIEQIPMSQCSNSKNLPEERETNSHTAEQPSVQQPPAAEEGPPLQLDLSYYSYEYDPDPYASEADVFEMVAELTTVSTFREADTIQEVVTTIE", "length": 1845, "header": "tr|A0A8V1AAY4-1|A0A8V1AFR7_CHICK Computationally mapped isoform of C3 and PZP like alpha-2-macroglobulin domain containing 8 OS=Gallus gallus OX=9031 GN=CPAMD8 PE=3 SV=1 CANONICAL=A0A8V1AFR7-1" }, "locus": { "chromosome": "28", "start_pos": 4699364, "end_pos": 4659963, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066136.1", "url": "https://www.ensembl.org/id/ENSGALT00010066136.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040402.1", "url": "https://www.ensembl.org/id/ENSGALP00010040402.1" } ] } }, { "isoform_ac": "A0A8V1AFR7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFR7/entry#A0A8V1AFR7-1", "sequence": { "sequence": "MHRAERRCAWGVLLTLCGLSAAQPRGRQGYLIAAPSVFRSGVEEAVSVTIFNAVKETTVQIQLVVKGETVSRGHGTVLDKGTIKLKVPSGLRGQGHLKVWGNRHVTEEGYIFHNYTTVTIDSKGSSVFIQTDKPVYKPKQKVLINLFTVTSDLRPFNDRIEAYVVDPRGSRMIEWNNLKPFCCGMVNMSFPLSDQPVFGEWLIFAEMQGHTYNKSFEVQKYVLPKFELLIDPPRYIRDLTACEKGTVHARYTFGKPVTGKLIVNMTINGVGYYRHEVGHPVLKTTQIDGSAVFDVCVKEMMPADVPEHFRGTVNIWATVVSSDGSKQVTFDDSTPVQKQLIDIKYSKDTRKQFKPGLPYKGKVEVTYPDGSPADRVTVRIKAELTPKDNVYTSELVSRNGLVEFEIPSIPTAAQYVWLETKVTAIDGRPSGDQYLPNYLSISSWYSPSKCHIQLQAPDKPFQVGEEAWIAVKSTCPCNFTLHYEVASRGNIVLSGLQPSNITQQRSKRATIPFEKSTDVTHFPGAAPTDIPAAEVEVCMTFLRFSVSHNMAPLGRLLVYYVRENGEGVTDSLQFSVKSTFENQVAVTLSANETRPGDVVNIKVRAAKSSCVCIATVDKSVYLLKTGFQLTASQVFKELAEYDVSDAFGAPKEEGHFWWPGMSSRRRRRSSVFPWHWDVTKDARFAFTETGLVVMTDTVSLNHRQNGGMYTDEAVPAFQPHTGTLVATMRSKMAQSRAEKRKRTFFPETWIWHCLNVSNTSGEAELHVEVPDSITTWITEAVGLSEEKGLGIASQTELKTFKPFFIDFTLPYHVIRGEQTKIPLTVYNYLTVCVEVHVKISVPKGIKFVGHPGKHHLTRKKCVAPGEAKPTSIVLSFSELGLSNITAKAFAYGGTNCCQNGMQALKNGKHSEDNYVDKRTPVGVDYVRSSVVIEPEGLSREYTYSVFFCPNEKIHISTPNKYEYQYMQKPAQMTHFDIAVKAHNDAHVALSSGPHDMAEMTEIVIGGHQNTKTWISISKMGEPVVSRDTAGILSWDEFRSFWISWKNGIIQVGHGTRVLNESIIVEWTVPKQFEVKYIGFSTGWGSIGEFKIWRKEETDENHNEAFTLGVPHNIIPGSERATASIIGDVMGPTLNNLDNLLRLPFGCGEQNMIHFAPNVFVLKYLQKTKQLSQEVESEATDYLVQGYQRQLTYKRQDGSYSAFGERDSSGSMWLTAFVLKSFAQSRGFIFIDPKELTAAKEWIIQHQKEDGSFPAMGRILNKDIQGGIHGKISLTAYVVASLLETGVTSEEERSAVDKAKHFLESNLHSAEDPYTTALTAYALTLLHSPAAAVALRKMNSMAITQDGFTHWSLTGSLVTDEDTFMGFNDGLSQSVVSAEVEMTSYALLTYTLLGDVASALPVVKWLSQQRNALGGFSSTQDTCVALQALAEYAILSYVGGVNLTISLASTNLDYQETFELNKMNKKVLQTAVIPSIPTGLFVSAKGEGCCLMQIDVTYNVPDPIAKPAFQLLVNLKEPKSEQHLQAPVLLRSLSPDENRSETLHRERAVVDDDDPAADRDHQEYKVILETCTRWLHSGSSNMAVLEVPLFSGFRADIESLEQLLMNKQIGLKRYEVDGRKVLFYFDEIPSQCMTCVKFQAFREYIVGKTAPVPIKVYDYYEPAFEATRFYNVSENSPLARELCDGPTCNEVESSASQWAGFSHSGPCNNIFGCLEDEYFEQCMCSRDCGYDGDPVCGSDGQIYQNHCQMEVASCRNNTRIEQIPMSQCSNSKNLPEERETNSHTAEQPSVQQPPAAEEGPPLQLDLSYYSYEYDPDPYASEADVFEMVAELTTVSTFREADTIQEVVTTIE", "length": 1850, "header": "tr|A0A8V1AFR7-1|A0A8V1AFR7_CHICK Isoform 1 of C3 and PZP like alpha-2-macroglobulin domain containing 8 OS=Gallus gallus OX=9031 GN=CPAMD8 PE=3 SV=1 CANONICAL=A0A8V1AFR7-1" }, "locus": { "chromosome": "28", "start_pos": 4699364, "end_pos": 4661460, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066128.1", "url": "https://www.ensembl.org/id/ENSGALT00010066128.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040394.1", "url": "https://www.ensembl.org/id/ENSGALP00010040394.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "E1BAA2-1", "protein_name": "C3 and PZP like alpha-2-macroglobulin domain containing 8", "gene_name": "CPAMD8", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAPGARRGGCEQRAPGGEAGTAALGPRPWPGPGQAPSPGAAPPRSGKMWGAQLGPLLRFLLLLLSPRDGVRAEQPQAPGYLIAAPSVFRSGVEEAISVTIFNSPREVMVQAQLVALGKAVAQSQGAIQDKGTIKLKVPTGLRGQALLKVWGRDWRVEEGPLFHNQTSVTVDSRGASVFIQTDKPVYRPKHRVLISIFTVTPDLRPTSEKLEAYILDPRGSRMMEWRHLEPLCCGITNMTFPLSDQPVLGEWFVFVEMQSHVFNRSFEVQKYVLPKFELLIDPPAYIRDLDTCETGTVQARYTFGKPVSGTLTINMTVNGVGYYSQEVGRPILRTTKIHGSQDFSICVKDMIPADVPEHFRGTISIWATVTAVDGSHQVAFDDSTPVQRQLVDVRYSKDTRKQFKPGLSYVGKVELSYPDGSPAEGVTVQIRAELTPKDNIYTVESVSQGGLVEFEIPSIPMSAQHVWLETKVTALSGKPVGAQYLPSYLSLSSWYSPSQCYLQLQPPSHPLQVGEDAYFPVKSTCPCNFTLYYEVAARGNIVLSGQQPAHVTQQRSKRAALEKPIRLMHLSETEPPPAPAAEVSVCMTSLQLAVTPSMVPLGRLLVFYVRENGEGVADSLQFTVETFFENQVSLTYSANETQPGEVVDLRLKAARGSCVCVAAVDKSVYLLRSGFRLTPAQVFRELEDYDVSDIFGVSREDGPFWWTGLTARRHRRSSVFLWPWGVTKDSGFAFAETGLVVMTDLVSLNHRQDGGLYTDEAVPAFQPHTGSLMAAVSSRQPPRAEKRKRTFFPETWVWHCLNISDPSGEETLSVQVPDSITSWVGEAVGLSPGRGLGIAEPTLLKTFKPFFIDFTLPPYVVRGEQAKIPLSIYNYMDTCAEVYMKISVPKGIQFVGHPGKRHLTKKMCVASGETEPMWVVLSFGDLGLSNITAKALAYRETSCCRDGKSVRPPEENYADRRVPIGRDHIRCSVMVEPEGAPRSYTYSAFFCPNERVHISTPNKYEFQYVQRPLRLTRFDVAVRAHNDARVALSPGPQDTAGMIEIVLGGHQNTRSWISTSKMGEPVASTPTAKILSWDEFRTFWISWHSGLIQVGHGPEPSNESVIMAWTLPKPPEVQFIGFSTGWGSVGEFRIWRKVEADESYSEAFTLGVPHSAIPGSERAAASIIGDVMGPTLNHLSNLLRLPFGCGEQNMIHFAPNVFVLKYLQKTRQLSPEVERETTDHLVQGYQRQLTYKHQDGSYSAFGERDESGSMWLTAFVLKSFAQARSFIFIDPLELEAAKDWIVQQQQADGSFPAVGRILNKDIQGGIHGTVPLTAYVVAALLEVDPASEEERGAITKARHFLESSASLVTDPYSSALTAYALTLLRSPAAPAALRKLRSLAITQDGVTHWSLTGSRDVDKDAFLSFSDGVYQTVVSAEVEMTAYALLTYTLLGDVATALPVVKWLSQQRNALGGFSSTQDTCVALQALAEYAILSYAGGVNLTVSLASTNLDYQETFELHRGNQKLLQMAAIPSLPTGLFVSARGEGCCLMQIDVTYNVPDPVAKPSFQLLVNLQEPEAEQQRPPSPASSADDDDPAADQHHQEYQVTLEVCTRWLHAGSSNMAVLEVPLLSGFRADVESLEQLLLDKHVALKRYELAGRRVLFYFDEIPSRCLTCVQFRALREHVVGRTSALPILVYDYYEPAFEATRFYNVSARSPLARELCAGPACNEVERALAQGPGWSPEERGPVAVPEEGVTVTRCGCARACSISGEPVCGSDGVVYASACHLQEAACRRRVRLEPAPPGRCALEQPTPALALYSYEYDLGPLDTGHLAAGHELVDLDKEAEDSQSGFSS", "length": 1839 }, "evidence": [ { "id": "A0A8V1AFR7", "url": "https://omabrowser.org/oma/group/A0A8V1AFR7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8IZJ3-1", "protein_name": "C3 and PZP-like alpha-2-macroglobulin domain-containing protein 8", "gene_name": "CPAMD8", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSGALLWPLLPLLLLLLSARDGVRAAQPQAPGYLIAAPSVFRAGVEEVISVTIFNSPREVTVQAQLVAQGEPVVQSQGAILDKGTIKLKVPTGLRGQALLKVWGRGWQAEEGPLFHNQTSVTVDGRGASVFIQTDKPVYRPQHRVLISIFTVSPNLRPVNEKLEAYILDPRGSRMIEWRHLKPFCCGITNMSFPLSDQPVLGEWFIFVEMQGHAYNKSFEVQKYVLPKFELLIDPPRYIQDLDACETGTVRARYTFGKPVAGALMINMTVNGVGYYSHEVGRPVLRTTKILGSRDFDICVRDMIPADVPEHFRGRVSIWAMVTSVDGSQQVAFDDSTPVQRQLVDIRYSKDTRKQFKPGLAYVGKVELSYPDGSPAEGVTVQIKAELTPKDNIYTSEVVSQRGLVGFEIPSIPTSAQHVWLETKVMALNGKPVGAQYLPSYLSLGSWYSPSQCYLQLQPPSHPLQVGEEAYFSVKSTCPCNFTLYYEVAARGNIVLSGQQPAHTTQQRSKRAAPALEKPIRLTHLSETEPPPAPEAEVDVCVTSLHLAVTPSMVPLGRLLVFYVRENGEGVADSLQFAVETFFENQVSVTYSANETQPGEVVDLRIRAARGSCVCVAAVDKSVYLLRSGFRLTPAQVFQELEDYDVSDSFGVSREDGPFWWAGLTAQRRRRSSVFPWPWGITKDSGFAFTETGLVVMTDRVSLNHRQDGGLYTDEAVPAFQPHTGSLVAVAPSRHPPRTEKRKRTFFPETWIWHCLNISDPSGEGTLSVKVPDSITSWVGEAVALSTSQGLGIAEPSLLKTFKPFFVDFMLPALIIRGEQVKIPLSVYNYMGTCAEVYMKLSVPKGIQFVGHPGKRHVTKKMCVAPGEAEPIWVVLSFSDLGLNNITAKALAYGDTNCCRDGRSSKHPEENHADRRVPIGVDHVRRSVMVEAEGVPRAYTYSAFFCPSERVHISTPNKYEFQYVQRPLRLTRFDVAVRAHNDARVALSSGPQDTAGMIEIVLGGHQNTRSWISTSKMGEPVASAHTAKILSWDEFRTFWISWRGGLIQVGHGPEPSNESVIVAWTLPRPPEVQFIGFSTGWGSMGEFRIWRKMEVDESYSEAFTLGVPHGAIPGSERATASIIGDVMGPTLNHLNNLLRLPFGCGEQNMIHFAPNVFVLKYLQKTQQLSPEVERETTDYLVQGYQRQLTYKRQDGSYSAFGERDASGSMWLTAFVLKSFAQARSFIFVDPRELAAAKSWIIQQQQADGSFLAVGRVLNKDIQGGIHGTVPLTAYVVVALLETGTASEEERGSTDKARHFLESAAPLAMDPYSCALTTYALTLLRSPAAPEALRKLRSLAIMRDGVTHWSLSNSWDVDKGTFLSFSDRVSQSVVSAEVEMTAYALLTYTLLGDVAAALPVVKWLSQQRNALGGFSSTQDTCVALQALAEYAILSYAGGINLTVSLASTNLDYQETFELHRTNQKVLQTAAIPSLPTGLFVSAKGDGCCLMQIDVTYNVPDPVAKPAFQLLVSLQEPEAQGRPPPMPASAAEGSRGDWPPADDDDPAADQHHQEYKVMLEVCTRWLHAGSSNMAVLEVPLLSGFRADIESLEQLLLDKHMGMKRYEVAGRRVLFYFDEIPSRCLTCVRFRALRECVVGRTSALPVSVYDYYEPAFEATRFYNVSTHSPLARELCAGPACNEVERAPARGPGWFPGESGPAVAPEEGAAIARCGCDHDCGAQGNPVCGSDGVVYASACRLREAACRQAAPLEPAPPSCCALEQRLPASSSSTYGDDLASVAPGPLQQDVKLNGAGLEVEDSDPEPEGEAEDRVTAGPRPPVSSGNLESSTQSASPFHRWGQTPAPQRHSGRVVGAHRPGLLSPVFVYSPAFQSGGEEGLWMSNTCTLR", "length": 1885 }, "evidence": [ { "id": "A0A8V1AFR7", "url": "https://omabrowser.org/oma/group/A0A8V1AFR7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "serine-type endopeptidase inhibitor activity", "id": "GO:0004867", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004867", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFR7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFR7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFR7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFR7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "eye development", "id": "GO:0001654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFR7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFR7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1059, "end_pos": 1061, "annotation": "n_glycosylation_sequon" }, { "start_pos": 114, "end_pos": 116, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1441, "end_pos": 1443, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1537, "end_pos": 1539, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1670, "end_pos": 1672, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1755, "end_pos": 1757, "annotation": "n_glycosylation_sequon" }, { "start_pos": 187, "end_pos": 189, "annotation": "n_glycosylation_sequon" }, { "start_pos": 213, "end_pos": 215, "annotation": "n_glycosylation_sequon" }, { "start_pos": 264, "end_pos": 266, "annotation": "n_glycosylation_sequon" }, { "start_pos": 478, "end_pos": 480, "annotation": "n_glycosylation_sequon" }, { "start_pos": 500, "end_pos": 502, "annotation": "n_glycosylation_sequon" }, { "start_pos": 591, "end_pos": 593, "annotation": "n_glycosylation_sequon" }, { "start_pos": 755, "end_pos": 757, "annotation": "n_glycosylation_sequon" }, { "start_pos": 758, "end_pos": 760, "annotation": "n_glycosylation_sequon" }, { "start_pos": 883, "end_pos": 885, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AFR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFR7" }, { "id": "PS51465", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51465" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Kazal-like", "eco_id": "ECO_0000259", "start_pos": 1722, "end_pos": 1769, "start_aa": "Met", "end_aa": "Asn", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1059, "end_pos": 1061 }, { "start_pos": 114, "end_pos": 116 }, { "start_pos": 1441, "end_pos": 1443 }, { "start_pos": 1537, "end_pos": 1539 }, { "start_pos": 1670, "end_pos": 1672 }, { "start_pos": 1755, "end_pos": 1757 }, { "start_pos": 187, "end_pos": 189 }, { "start_pos": 213, "end_pos": 215 }, { "start_pos": 264, "end_pos": 266 }, { "start_pos": 478, "end_pos": 480 }, { "start_pos": 500, "end_pos": 502 }, { "start_pos": 591, "end_pos": 593 }, { "start_pos": 755, "end_pos": 757 }, { "start_pos": 758, "end_pos": 760 }, { "start_pos": 883, "end_pos": 885 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AF70-1", "uniprot_ac": "A0A8V1AF70", "uniprot_id": "A0A8V1AF70_CHICK", "mass": { "chemical_mass": 49131.0, "monoisotopic_mass": 49131.0 }, "refseq": { "ac": "XP_415423", "name": "divergent protein kinase domain 1B isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_415423" }, "gene_names": [ { "name": "FAM69B", "type": "recommended", "evidence": [ { "id": "A0A8V1AF70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF70" } ] }, { "name": "FAM69B", "type": "synonym", "evidence": [ { "id": "XP_415423", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_415423" } ] } ], "protein_names": [ { "name": "Divergent protein kinase domain 1B", "type": "synonym", "evidence": [ { "id": "A0A8V1AF70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF70/entry#names_and_taxonomy" } ] }, { "name": "divergent protein kinase domain 1B isoform X1", "type": "synonym", "evidence": [ { "id": "XP_415423", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_415423" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052548.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_415423.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_415423", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_415423" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AF70", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF70" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FAM69B", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF70", "locus": {} } ], "crossref": [ { "id": "A0A8V1AF70", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AF70", "database": "AlphaFoldDB", "categories": [] }, { "id": "417139", "url": "https://www.ncbi.nlm.nih.gov/gene/417139", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022049", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022049", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029244", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029244", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "WALLHIN", "url": "https://omabrowser.org/oma/group/WALLHIN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A4Y1", "url": "https://www.orthodb.org/?gene=A0A8V1A4Y1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AF70", "url": "https://www.orthodb.org/?gene=A0A8V1AF70", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21093", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21093", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21093:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21093:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12260", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12260", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14875", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14875", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_415423", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_415423", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1A4Y1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Y1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A4Y1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Y1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AF70", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF70", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AF70-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF70-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRRVRRLVHLVLFCPISKGLQSRLPGIKVKYLLVVWLGIFVGSWVAYMHYSSYSELCRGHVCRMIICDQYKKGIISGSTCKDLCEEHSLRFQHCLSSSPTQQVYSGLWKEKEVIIKCGIEEALKADSNPDSVPRRDVVLFDKPTRGTSMDEFKEMLLNFLKSNLGDQTSLAALVSQIITMADVNRDGKVSLAEAKSIWALLQLNEFLLMLSLHEKEHTSKLLGYCGDLYVTEKIPHNSLYGADIPAFLQSLLPAAVHQVVHQWFAPAWPWRAKITIGLLEFVEEIFHGTYGNFYICETSFRNVGYNDKYDFKMVNLRKVATEMTIRGFLKGRHCEQNVDCTYGKDCMATCDKLMKQCKSDMVQPNLAKVCGLLQDYLLYGAPPDLKEELQKQLRTCMTLSGLASQMEVHHSLVLNNLKTLLWKKISNTKYS", "length": 431, "header": "tr|A0A8V1AF70-1|A0A8V1AF70_CHICK Isoform 1 of Divergent protein kinase domain 1B OS=Gallus gallus OX=9031 GN=FAM69B PE=3 SV=1 CANONICAL=A0A8V1AF70-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A4Y1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF70/entry#A0A8V1A4Y1-1", "sequence": { "sequence": "MRRVRRLVHLVLFCPISKGLQSRLPGIKVKYLLVVWLGIFVGSWVAYMHYSSYSELCRGHVCRMIIVYSGLWKEKEVIIKCGIEEALKADSNPDSVPRRDVVLFDKPTRGTSMDEFKEMLLNFLKSNLGDQTSLAALVSQIITMADVNRDGKVSLAEAKSIWALLQLNEFLLMLSLHEKEHTSKLLGYCGDLYVTEKIPHNSLYGADIPAFLQSLLPAAVHQVVHQWFAPAWPWRAKITIGLLEFVEEIFHGTYGNFYICETSFRNVGYNDKYDFKMVNLRKVATEMTIRGFLKGRHCEQNVDCTYGKDCMATCDKLMKQCKSDMVQPNLAKVCGLLQDYLLYGAPPDLKEELQKQLRTCMTLSGLASQMEVHHSLVLNNLKTLLWKKISNTKYS", "length": 395, "header": "tr|A0A8V1A4Y1-1|A0A8V1AF70_CHICK Computationally mapped isoform of Divergent protein kinase domain 1B OS=Gallus gallus OX=9031 GN=FAM69B PE=3 SV=1 CANONICAL=A0A8V1AF70-1" }, "locus": { "chromosome": "17", "start_pos": 8338736, "end_pos": 8334623, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066990.1", "url": "https://www.ensembl.org/id/ENSGALT00010066990.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040969.1", "url": "https://www.ensembl.org/id/ENSGALP00010040969.1" } ] } }, { "isoform_ac": "A0A8V1AF70-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF70/entry#A0A8V1AF70-1", "sequence": { "sequence": "MRRVRRLVHLVLFCPISKGLQSRLPGIKVKYLLVVWLGIFVGSWVAYMHYSSYSELCRGHVCRMIICDQYKKGIISGSTCKDLCEEHSLRFQHCLSSSPTQQVYSGLWKEKEVIIKCGIEEALKADSNPDSVPRRDVVLFDKPTRGTSMDEFKEMLLNFLKSNLGDQTSLAALVSQIITMADVNRDGKVSLAEAKSIWALLQLNEFLLMLSLHEKEHTSKLLGYCGDLYVTEKIPHNSLYGADIPAFLQSLLPAAVHQVVHQWFAPAWPWRAKITIGLLEFVEEIFHGTYGNFYICETSFRNVGYNDKYDFKMVNLRKVATEMTIRGFLKGRHCEQNVDCTYGKDCMATCDKLMKQCKSDMVQPNLAKVCGLLQDYLLYGAPPDLKEELQKQLRTCMTLSGLASQMEVHHSLVLNNLKTLLWKKISNTKYS", "length": 431, "header": "tr|A0A8V1AF70-1|A0A8V1AF70_CHICK Isoform 1 of Divergent protein kinase domain 1B OS=Gallus gallus OX=9031 GN=FAM69B PE=3 SV=1 CANONICAL=A0A8V1AF70-1" }, "locus": { "chromosome": "17", "start_pos": 8338736, "end_pos": 8334623, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066988.1", "url": "https://www.ensembl.org/id/ENSGALT00010066988.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040967.1", "url": "https://www.ensembl.org/id/ENSGALP00010040967.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0AAA9TJW0-1", "protein_name": "Divergent protein kinase domain 1B", "gene_name": "DIPK1B", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRARRPAGLRPSGGEPGPRTARAHHAAAAAPGAPGALLPLLQGPAGPAPRPEGQVCLPGLAGRPRRQLAGLRALFVLRGALPRPCLQSGHPPPTCRGLRGPGGADKERAPPNQRICSFRLPRAPWPSHQRQSGLPGCWAAGIPPPFPRRPGHLTGCDQYRKGIISGSICQDLCNLQQVEWRTCLSSVPGQQVYSGLWQGKEVTIKCGLEESLSWKAGADVAPRRELVLFDKPTRGTSIKEFREMTLSFLKANLGDLPSLPALVGQVLLMADFNKDSRVSLAEARSLWALLQRNEFLLLLSLQGRGHAAPLLGHCGDLYVTEGVPRSSGPAAALPALLRPLLPPALHGALQQWLGPAWPWRAKIAIGLLEFVEELFHGAYGTFYMCETTLANVGYTAKYDFRMADLQQVAPEAAVRRFLRGRHCERSADCTYGHDCRAPCDTLLRQCKGDLVQPNLAKVCELLRDYLLPGAPAGLRAELGRQLRTCTTLSGLASQVEAHHSLVLSHLKTLLWKEISNTKYT", "length": 520 }, "evidence": [ { "id": "A0A8V1AF70", "url": "https://omabrowser.org/oma/group/A0A8V1AF70/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1RVZ5-1", "protein_name": "Divergent protein kinase domain 1B", "gene_name": "DIPK1B", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRRLRRLAHLVLFCPFSKGLQGRLPGLRVKYVFLVWLGVFAGSWMAYTHYSSYAELCRGHICQVVICDQFRKGIISGSICQDLCHLHQVEWRTCLSSVPGQQVYSGLWQGKEVTIKCGIEESLNSKAGSDGAPRRELVLFDKPSRGTSIKEFREMTLSFLKANLGDLPSLPALVGRVLLMADFNKDNRVSLAEAKSVWALLQRNEFLLLLSLQEKEHASRLLGYCGDLYVTEGVPLSSWPGATLPPLLRPLLPPALHGALQQWLGPAWPWRAKIAMGLLEFVEDLFHGAYGNFYMCETTLANVGYTAKYDFRMADLQQVAPEAAVRRFLRGRRCEHSADCTYGRDCRAPCDTLMRQCKGDLVQPNLAKVCELLRDYLLPGAPAALRPELGKQLRTCTTLSGLASQVEAHHSLVLSHLKSLLWKEISDSRYT", "length": 431 }, "evidence": [ { "id": "A0A8V1AF70", "url": "https://omabrowser.org/oma/group/A0A8V1AF70/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q5FVL3-1", "protein_name": "Divergent protein kinase domain 1B", "gene_name": "Dipk1b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRRLRRLVHLVLLCPFSKGLQGRLPGLRVKYVLLVWLGIFVGSWMVYVHYSSYSELCRGHVCQVVICDQYQKGIISGSVCQDLCELQKVEWRTCLSSAPGQQVYSGLWQDKEVTIKCGIEEALNSKAWPDAVPRRELVLFDKPTRGTSIKEFREMTLSFLKANLGDLPSLPALVDQILLMADFNKDSRVSLAEAKSVWALLQRNEFLLLLSLQEKEHASRLLGYCGDLYLTESIPHGSWHGAVLLPALRPLLPSVLHRALQQWFGPAWPWRAKIAIGLLEFVEELFHGSYGTFYMCETTLANVGYTATYDFKMADLQQVAPEATVRRFLQGRHCEQSSDCIYGRDCRAPCDKLMRQCKGDLIQPNLAKVCELLRDYLLPGAPADLYEELGKQLRTCTTLSGLASQVEAHHSLVLSHLKTLLWREISNTNYS", "length": 431 }, "evidence": [ { "id": "A0A8V1AF70", "url": "https://omabrowser.org/oma/group/A0A8V1AF70/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5VUD6-1", "protein_name": "Divergent protein kinase domain 1B", "gene_name": "DIPK1B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRRLRRLAHLVLFCPFSKRLQGRLPGLRVRCIFLAWLGVFAGSWLVYVHYSSYSERCRGHVCQVVICDQYRKGIISGSVCQDLCELHMVEWRTCLSVAPGQQVYSGLWRDKDVTIKCGIEETLDSKARSDAAPRRELVLFDKPTRGTSIKEFREMTLSFLKANLGDLPSLPALVGQVLLMADFNKDNRVSLAEAKSVWALLQRNEFLLLLSLQEKEHASRLLGYCGDLYLTEGVPHGAWHAAALPPLLRPLLPPALQGALQQWLGPAWPWRAKIAIGLLEFVEELFHGSYGTFYMCETTLANVGYTATYDFKMADLQQVAPEATVRRFLQGRRCEHSTDCTYGRDCRAPCDRLMRQCKGDLIQPNLAKVCALLRGYLLPGAPADLREELGTQLRTCTTLSGLASQVEAHHSLVLSHLKTLLWKKISNTKYS", "length": 431 }, "evidence": [ { "id": "A0A8V1AF70", "url": "https://omabrowser.org/oma/group/A0A8V1AF70/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q99ML4-1", "protein_name": "Divergent protein kinase domain 1B", "gene_name": "Dipk1b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRRLRRLVHLVLLCPFSKGLQGRLPGLRVKYVLLVWLGIFVGSWMVYVHYSSYSELCRGHVCQVVICDQYRKGIISGSVCQDLCELQKVEWRTCLSSAPGQQVYSGLWQDKEVTIKCGIEEALNSKAWPDAAPRRELVLFDKPTRGTSIKEFREMTLSFLKANLGDLPSLPALVDQILLMADFNKDSRVSLAEAKSVWALLQRNEFLLLLSLQEKEHASRLLGYCGDLYLTEGIPHGSWHGAVLLPALRPLLPSVLHRALQQWFGPAWPWRAKIAIGLLEFVEELFHGSYGTFYMCETTLANVGYTATYDFKMADLQQVAPEATVRRFLQGRHCEQSSDCIYGRDCRAPCDRLMRQCKGDLIQPNLAKVCELLRDYLLPGAPAGLYEELGKQLRTCTTLSGLASQIEAHHSLVLSHLKTLLWREISNTNYS", "length": 431 }, "evidence": [ { "id": "A0A8V1AF70", "url": "https://omabrowser.org/oma/group/A0A8V1AF70/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AF70", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF70" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AF70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF70" }, { "id": "SM01299", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM01299" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "FAM69 N-terminal", "eco_id": "ECO_0000259", "start_pos": 22, "end_pos": 180, "start_aa": "Ser", "end_aa": "Met", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AFP0-1", "uniprot_ac": "A0A8V1AFP0", "uniprot_id": "A0A8V1AFP0_CHICK", "mass": { "chemical_mass": 69804.0, "monoisotopic_mass": 69804.0 }, "refseq": {}, "gene_names": [ { "name": "LOC107050775", "type": "recommended", "evidence": [ { "id": "A0A8V1AFP0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFP0" } ] } ], "protein_names": [ { "name": "EPS8 signaling adaptor L3", "type": "synonym", "evidence": [ { "id": "A0A8V1AFP0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFP0/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFP0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFP0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC107050775", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFP0", "locus": {} } ], "crossref": [ { "id": "A0A8V1AFP0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AFP0", "database": "AlphaFoldDB", "categories": [] }, { "id": "107050775", "url": "https://www.ncbi.nlm.nih.gov/gene/107050775", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013625", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013625", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013761", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013761", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036028", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036028", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039801", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039801", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041418", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041418", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055093", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055093", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:107050775", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:107050775", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WTGNEPP", "url": "https://omabrowser.org/oma/group/WTGNEPP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A5D9", "url": "https://www.orthodb.org/?gene=A0A8V1A5D9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AAA4", "url": "https://www.orthodb.org/?gene=A0A8V1AAA4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AFP0", "url": "https://www.orthodb.org/?gene=A0A8V1AFP0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12287", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12287", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12287:SF22", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12287:SF22", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00018", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00018", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08416", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08416", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18016", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18016", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22975", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22975", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1A5D9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5D9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A5D9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5D9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AAA4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAA4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AAA4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAA4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFP0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFP0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFP0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFP0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSRAQLRIPPAVSPAALQRPNLICSERVRAATQIPAWPDSLHRASAAAAPARSTAVRMGDPFAHWSGSAARTEYEDSPHGPASFARPSAKSIYNQRKDYGQTLLKPQSDFQHHVEHLLTLRLERELRGAEDCVGRLRELEAQGKVWGQDVLLGVRGHELLLSDVESREDLDSFPLSSIQDCLATPDVGSYDSVLAVSVQERGRGGSSVLLFHCHHIGAGTLKSSLEKLVRQRKEEQRQYGNVPETPPDPPYIPVSYRAAEPWAEHSGPQSLPPIQHKPPSEYGADQNIWMGPNGEVMSDPERDVLVLNHVLGDMELLVGRLRGSAGSTKTPKKKKKKKKKDLPSKAEYVDFFQKAKYALNLLAYNWQHIRTPSGPELLDLIFQTLTSVLEQCPHPHLAEEVETPLLLPEALQLLEGTLLPEQHRTWQSLGMAWHRSRAQYPNADQVPRYVPTFSDGWLPPPMLTADYQPVLDGNPPGYRDAPGQLPPPHPPTAVRALYEFQGRNPQELSVRMGDTLQVLDQQKKWWLVRSRGGQQGYVPSNILEPVGHEDGSQGSPPTLHVGSSPAEVTAWLKDKGFSPLTVRCLGVLGGQQLLQMRAAELRAVCPEEWRRVLFKLSSARSALGMDPTD", "length": 629, "header": "tr|A0A8V1AFP0-1|A0A8V1AFP0_CHICK Isoform 1 of EPS8 signaling adaptor L3 OS=Gallus gallus OX=9031 GN=LOC107050775 PE=3 SV=1 CANONICAL=A0A8V1AFP0-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A5D9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFP0/entry#A0A8V1A5D9-1", "sequence": { "sequence": "MGDPFAHWSGSAARTEYEDSPHGPASFARPSAKSIYNQRKDYGQTLLKPQSDFQHHVEHLLTLRLERELRGAEDCVGRLRELEAQGKVWGQDVLLGVRGHELLLSDVESREDLDSFPLSSIQDCLATPDVGSYDSVLAVSVQERGRGGSSVLLFHCHHIGAGTLKSSLEKLVRQRKEEQRQYGNVPETPPDPPYIPVSYRAAEPWAEHSGPQSLPPIQHKPPSEYGADQNIWMGPNGEVMSDPERDVLVLNHVLGDMELLVGRLRGSAGSTKTPKKKKKKKKKDLPSKAEYVDFFQKAKYALNLLAYNWQHIRTPSGPELLDLIFQTLTSVLEQCPHPHLAEEVETPLLLPEALQLLEGTLLPEQHRTWQSLGMAWHRSRAQYPNADQVPRYVPTFSDGWLPPPMLTADYQPVWGGCVGGHSPVPQFPTTRRSVPQVLDGNPPGYRDAPGQLPPPHPPTAVRALYEFQGRNPQELSVRMGDTLQVLDQQKKWWLVRSRGGQQGYVPSNILEPVGHEDGSQGSPPTLHVGSSPAEVTAWLKDKGFSPLTVRCLGVLGGQQLLQMRAAELRAVCPEEWRRVLFKLSSARSALGMDPTD", "length": 596, "header": "tr|A0A8V1A5D9-1|A0A8V1AFP0_CHICK Computationally mapped isoform of EPS8 signaling adaptor L3 OS=Gallus gallus OX=9031 GN=LOC107050775 PE=3 SV=1 CANONICAL=A0A8V1AFP0-1" }, "locus": { "chromosome": "26", "start_pos": 1314558, "end_pos": 1308516, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067220.1", "url": "https://www.ensembl.org/id/ENSGALT00010067220.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041124.1", "url": "https://www.ensembl.org/id/ENSGALP00010041124.1" } ] } }, { "isoform_ac": "A0A8V1AAA4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFP0/entry#A0A8V1AAA4-1", "sequence": { "sequence": "MGDPFAHWSGSAARTEYEDSPHGPASFARPSAKSIYNQRKDYGQTLLKPQSDFQHHVEHLLTLRLERELRGAEDCVGRLRELEAQGKVWGQDVLLGVRGHELLLSDVESREDLDSFPLSSIQDCLATPDVGSYDSVLAVSVQERGRGGSSVLLFHCHHIGAGTLKSSLEKLVRQRKEEQRQYGNVPETPPDPPYIPVSYRAAEPWAEHSGPQSLPPIQHKPPSEYGADQNIWMGPNGEVMSDPERDVLVLNHVLGDMELLVGRLRGSAGSTKTPKKKKKKKKKDLPSKAEYVDFFQKAKYALNLLAYNWQHIRTPSGPELLDLIFQTLTSVLEQCPHPHLAEEVETPLLLPEALQLLEGTLLPEQHRTWQSLGMAWHRSRAQYPNADQVPRYVPTFSDGWLPPPMLTADYQPVLDGNPPGYRDAPGQLPPPHPPTAVRALYEFQGRNPQELSVRMGDTLQVLDQQKKWWLVRSRGGQQGYVPSNILEPVGHEDGSQGSPPTLHVGSSPAEVTAWLKDKGFSPLTVRCLGVLGGQQLLQMRAAELRAVCPEEWRRVLFKLSSARSALGMDPTD", "length": 572, "header": "tr|A0A8V1AAA4-1|A0A8V1AFP0_CHICK Computationally mapped isoform of EPS8 signaling adaptor L3 OS=Gallus gallus OX=9031 GN=LOC107050775 PE=3 SV=1 CANONICAL=A0A8V1AFP0-1" }, "locus": { "chromosome": "26", "start_pos": 1314558, "end_pos": 1308516, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067222.1", "url": "https://www.ensembl.org/id/ENSGALT00010067222.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041126.1", "url": "https://www.ensembl.org/id/ENSGALP00010041126.1" } ] } }, { "isoform_ac": "A0A8V1AFP0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFP0/entry#A0A8V1AFP0-1", "sequence": { "sequence": "MSRAQLRIPPAVSPAALQRPNLICSERVRAATQIPAWPDSLHRASAAAAPARSTAVRMGDPFAHWSGSAARTEYEDSPHGPASFARPSAKSIYNQRKDYGQTLLKPQSDFQHHVEHLLTLRLERELRGAEDCVGRLRELEAQGKVWGQDVLLGVRGHELLLSDVESREDLDSFPLSSIQDCLATPDVGSYDSVLAVSVQERGRGGSSVLLFHCHHIGAGTLKSSLEKLVRQRKEEQRQYGNVPETPPDPPYIPVSYRAAEPWAEHSGPQSLPPIQHKPPSEYGADQNIWMGPNGEVMSDPERDVLVLNHVLGDMELLVGRLRGSAGSTKTPKKKKKKKKKDLPSKAEYVDFFQKAKYALNLLAYNWQHIRTPSGPELLDLIFQTLTSVLEQCPHPHLAEEVETPLLLPEALQLLEGTLLPEQHRTWQSLGMAWHRSRAQYPNADQVPRYVPTFSDGWLPPPMLTADYQPVLDGNPPGYRDAPGQLPPPHPPTAVRALYEFQGRNPQELSVRMGDTLQVLDQQKKWWLVRSRGGQQGYVPSNILEPVGHEDGSQGSPPTLHVGSSPAEVTAWLKDKGFSPLTVRCLGVLGGQQLLQMRAAELRAVCPEEWRRVLFKLSSARSALGMDPTD", "length": 629, "header": "tr|A0A8V1AFP0-1|A0A8V1AFP0_CHICK Isoform 1 of EPS8 signaling adaptor L3 OS=Gallus gallus OX=9031 GN=LOC107050775 PE=3 SV=1 CANONICAL=A0A8V1AFP0-1" }, "locus": { "chromosome": "26", "start_pos": 1325250, "end_pos": 1308516, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067223.1", "url": "https://www.ensembl.org/id/ENSGALT00010067223.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041127.1", "url": "https://www.ensembl.org/id/ENSGALP00010041127.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:107050775", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:107050775", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A286ZU37-1", "protein_name": "Epidermal growth factor receptor kinase substrate 8-like protein 3", "gene_name": "EPS8L3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSRPSSRAIYLHRKEYVQNLASEPTHLQHRVEHLMTCKLGTQRVQEPKDALQKLQEMDTQGRVWSQDLLLQVRDGWLQLLDIETKEELESYRLDSIKVMDVALDTCSYNSVLSITVQDSGLRDVSTLLFQCPEVGAERLKTSLQKALEEDLEQRPRFGALHPDQDRWRGPPLERPLPKEQAPSFERGPPPEQPHWMAPEQNTPPSPRPLPHPSSVHERSAFTLPPSRRPPSPENPERDEEVLNHVLKDIELFVGKLKEAQALSKTSRKKKRWRKKTKKGGVTEAHYIDCFQKIKYSFNLLGKLAIRLQETSAPEFIHILFQTLDFILAQCPEPDLAAQVISPLLTTKAIDLLQSCLSPLENSLWKGLGKAWTTSQANWTGSEPLPYQPTFYDGWQLPELTYQALSRYQDTTSLRGSPSLESTLHFAQEEAYNHSPKLGPSRPGSVKPGLQMQVLYEFEARNSQELTVVQGEVLEILDQSKRWWLVKNEMGRSGYIPSNILEPLQSGAPRSQNGSPSRAPMLRLSSRPEEVTAWLQAENFSTVTVRTLGSLTGSQLLHMRPGELQMLCPREAPRVLARLEAVRRMLGISP", "length": 589 }, "evidence": [ { "id": "A0A8V1AFP0", "url": "https://omabrowser.org/oma/group/A0A8V1AFP0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "M0R3R8-1", "protein_name": "Epidermal growth factor receptor kinase substrate 8-like protein 3", "gene_name": "Eps8l3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTQIGLQNVLQVQVGLCLRRWQRSQNRTPSDNTGPLAQASASLGDQTPDCTGNQEAVLSSVDMSRPSSRAIYLHRKEYSQSLASEPTLLQHRVEHLMTCKLGTQRVREPKDALQKLQEMDAQGRVWSQNLFLQVKDGWLQLLDIETKEDLDSYRLDNIKAIDVALNTCSYDSILSVTVQESGLPGISTMLFQCQEVGAEQLRTSLQKALEEELEERPRFGVHHPGQDRWKGSPLQRPIPIHQAPPLEQRFSPEPRFPPERPHDMTPERSITPSSRSLTHYPSAREPNGFTLPPPPRRAPSPENPERDEEVLNHVLRDIELFSGKLKEIQAKNSHKKIKLGRKKKKYQKEITQAQYIDCFQKIKFSFNLLGKLALRLQETSAPEFVGLIFQTLRFILSQCPEADLTTKVISPLLTPKAIDLLQSCLSPPERTLWKSLGTAWTTSWADWTGSEPPPYQPTFYDGWQIPEPYSTKPLRNQDSLSLRGSRMRSSLHFPQDEPYNDSREYEDSNLPLPSPSPDRTALKMQVLYEFEARNAQELTVAQGEILEILDQSKRWWLVKNEAGLTGYIPSNILEPLPAGAPRGHRQSSFRAPMLRLSSKPEEVTAWLQAENFSTVTVRTLGSLVGSQLLHMRLGELQMLCPQEAPRIQARLEAVRRMLGMTH", "length": 662 }, "evidence": [ { "id": "A0A8V1AFP0", "url": "https://omabrowser.org/oma/group/A0A8V1AFP0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8TE67-1", "protein_name": "Epidermal growth factor receptor kinase substrate 8-like protein 3", "gene_name": "EPS8L3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSRPSSRAIYLHRKEYSQNLTSEPTLLQHRVEHLMTCKQGSQRVQGPEDALQKLFEMDAQGRVWSQDLILQVRDGWLQLLDIETKEELDSYRLDSIQAMNVALNTCSYNSILSITVQEPGLPGTSTLLFQCQEVGAERLKTSLQKALEEELEQRPRLGGLQPGQDRWRGPAMERPLPMEQARYLEPGIPPEQPHQRTLEHSLPPSPRPLPRHTSAREPSAFTLPPPRRSSSPEDPERDEEVLNHVLRDIELFMGKLEKAQAKTSRKKKFGKKNKDQGGLTQAQYIDCFQKIKHSFNLLGRLATWLKETSAPELVHILFKSLNFILARCPEAGLAAQVISPLLTPKAINLLQSCLSPPESNLWMGLGPAWTTSRADWTGDEPLPYQPTFSDDWQLPEPSSQAPLGYQDPVSLRRGSHRLGSTSHFPQEKTHNHDPQPGDPNSRPSSPKPAQPALKMQVLYEFEARNPRELTVVQGEKLEVLDHSKRWWLVKNEAGRSGYIPSNILEPLQPGTPGTQGQSPSRVPMLRLSSRPEEVTDWLQAENFSTATVRTLGSLTGSQLLRIRPGELQMLCPQEAPRILSRLEAVRRMLGISP", "length": 593 }, "evidence": [ { "id": "A0A8V1AFP0", "url": "https://omabrowser.org/oma/group/A0A8V1AFP0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q91WL0-1", "protein_name": "Epidermal growth factor receptor kinase substrate 8-like protein 3", "gene_name": "Eps8l3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSRPSSRAIYLHRKEYSQSMASEPTLLQHRVEHLMTCKLGTQRVREPKDALQKLQEMDAQGRVWSQDLFLQVRDGWLHLLDIETKEELDSYRLDNIKAIDVALNTCSYNSILSVTVQESGLPGISTLLFQCQEVGAEQLRTSLQKALEEELEERPRFGVHHPSQDRWKGPPLERPLPIQQAPPLEQRFSPEHRFPPEQPHNMTSERSISPSSRSLTHYPSAREPNGFTLPPPPRRAPSPEDPERDEEVLNHVLRDIELFAGKLKEVQARNSHKKTKLGRKKKKSKNGITQAEYIDCFQKIKLSFNLLGKLALRMQETSAPEFVGLIFQTLKFILSQCPEAGLPAKVISPLLTPKAIDLLQSCLSPPEDTLWKSLGTSWTTSWADWTGSEPPPYQPTFYDGWQIPQPRSMMPITNQDSISLRGSRMRSSLHFPRDEPYNHNPEYEDSNLPLSSPSPGRAALKMQVLYEFEARNAQELTVAQGEILEVLDQSKRWWLVKNEAGLTGYIPSNILEPLPAGAPRGHRQPSFRAPMLRLSSKPEEVTAWLQAENFSTVTVRTLGSLMGSQLLHMRPGELQMLCPQEAPRIQARLDAVRRMLGMTH", "length": 600 }, "evidence": [ { "id": "A0A8V1AFP0", "url": "https://omabrowser.org/oma/group/A0A8V1AFP0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFP0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFP0" } ], "pmid": "" }, { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFP0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFP0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFP0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFP0" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFP0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFP0" } ], "pmid": "" }, { "name": "ruffle membrane", "id": "GO:0032587", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032587", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFP0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFP0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "Rho protein signal transduction", "id": "GO:0007266", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007266", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFP0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFP0" } ], "pmid": "" }, { "name": "regulation of Rho protein signal transduction", "id": "GO:0035023", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035023", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFP0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFP0" } ], "pmid": "" }, { "name": "positive regulation of ruffle assembly", "id": "GO:1900029", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900029", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFP0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFP0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AFP0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFP0" }, { "id": "PS50002", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50002" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SH3", "eco_id": "ECO_0000259", "start_pos": 489, "end_pos": 548, "start_aa": "His", "end_aa": "His", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AFW1-1", "uniprot_ac": "A0A8V1AFW1", "uniprot_id": "A0A8V1AFW1_CHICK", "mass": { "chemical_mass": 55963.0, "monoisotopic_mass": 55963.0 }, "refseq": { "ac": "XP_415568", "name": "UDP-N-acetylhexosamine pyrophosphorylase-like protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_415568" }, "gene_names": [ { "name": "UAP1L1", "type": "recommended", "evidence": [ { "id": "A0A8V1AFW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFW1" } ] }, { "name": "UAP1L1", "type": "synonym", "evidence": [ { "id": "XP_415568", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_415568" } ] } ], "protein_names": [ { "name": "UDP-N-acetylglucosamine pyrophosphorylase 1 like 1", "type": "synonym", "evidence": [ { "id": "A0A8V1AFW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFW1/entry#names_and_taxonomy" } ] }, { "name": "UDP-N-acetylhexosamine pyrophosphorylase-like protein 1", "type": "synonym", "evidence": [ { "id": "XP_415568", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_415568" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052548.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_415568.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_415568", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_415568" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFW1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFW1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "UAP1L1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFW1", "locus": { "chromosome": "17", "start_pos": 1029229, "end_pos": 1054070, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027789", "url": "https://www.ensembl.org/id/ENSGALG00010027789" } ] } } ], "crossref": [ { "id": "A0A8V1AFW1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AFW1", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd04193", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04193", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "417295", "url": "https://www.ncbi.nlm.nih.gov/gene/417295", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002618", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002618", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029044", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029044", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039741", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039741", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:417295", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417295", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "THCTVPW", "url": "https://omabrowser.org/oma/group/THCTVPW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A5M1", "url": "https://www.orthodb.org/?gene=A0A8V1A5M1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ADA4", "url": "https://www.orthodb.org/?gene=A0A8V1ADA4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AFW1", "url": "https://www.orthodb.org/?gene=A0A8V1AFW1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11952", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11952", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11952:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11952:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01704", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01704", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_415568", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_415568", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1A5M1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5M1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A5M1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5M1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ADA4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADA4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ADA4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADA4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFW1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFW1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFW1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFW1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEPPEEVRARLERAGQGHLLRFWAELDPAQRAELLAALPPGLGEHCRLAAACARPRERLERLDGRVEPLPAAVLGSVRHCGPAALQRWEDEGLHQISQNKVAVLLLAGGQGTRLGVSYPKGMYNVGLPSGKTLYQIQAERIRKVEQLAGQRHHCKCTIPWYIMTSEFTLGPTEEFFVKHSYFNLDKANVIMFEQRMLPAVTFDGKAILEEKGKIAMAPDGNGGLYRALVDNKILDDMKQRGIQYVHVYCVDNILVKMADPVFIGFCVAKGADCGAKVVEKAYPTEPIGVVCRVDGVSHVVVEYSEISPETAQQRRPDGGLMYSVGNICNHFFTVEFLQTVAQKHESQLKHHVAIKKVPYIDEEGNLVKPLKPNGIKLEKFVFDVFQFSKNFVAFEVLREEEFSPLKNADTAETDNPTTARQSLLAQHYRWALKAGARFLDEDGCRIPEKLSLSGTEDPPAVCEISPLVSYFGEGLEAYMKNKDFCSPFILDEDKAEMLRSC", "length": 501, "header": "tr|A0A8V1AFW1-1|A0A8V1AFW1_CHICK Isoform 1 of UDP-N-acetylglucosamine pyrophosphorylase 1 like 1 OS=Gallus gallus OX=9031 GN=UAP1L1 PE=1 SV=1 CANONICAL=A0A8V1AFW1-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A5M1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFW1/entry#A0A8V1A5M1-1", "sequence": { "sequence": "MPKEEQHTSVDSYLLKQSPKTKELCHVPEENFNPHACNGLWNQGGHPAGGQSCSGRAEIAEKRAAFLHSCAAGAALSYTGKRQAEICLHQISQNKVAVLLLAGGQGTRLGVSYPKGMYNVGLPSGKTLYQIQAERIRKVEQLAGQRHHCKCTIPWYIMTSEFTLGPTEEFFVKHSYFNLDKANVIMFEQRMLPAVTFDGKAILEEKGKIAMAPDGNGGLYRALVDNKILDDMKQRGIQYVHVYCVDNILVKMADPVFIGFCVAKGADCGAKVVEKAYPTEPIGVVCRVDGVSHVVVEYSEISPETAQQRRPDGGLMYSVGNICNHFFTVEFLQTVAQKHESQLKHHVAIKKVPYIDEEGNLVKPLKPNGIKLEKFVFDVFQFSKNFVAFEVLREEEFSPLKNADTAETDNPTTARQSLLAQHYRWALKAGARFLDEDGCRIPEKLSLSGTEDPPAVCEISPLVSYFGEGLEAYMKNKDFCSPFILDEDKAEMLRSC", "length": 496, "header": "tr|A0A8V1A5M1-1|A0A8V1AFW1_CHICK Computationally mapped isoform of UDP-N-acetylglucosamine pyrophosphorylase 1 like 1 OS=Gallus gallus OX=9031 GN=UAP1L1 PE=1 SV=1 CANONICAL=A0A8V1AFW1-1" }, "locus": { "chromosome": "17", "start_pos": 1053871, "end_pos": 1031623, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067341.1", "url": "https://www.ensembl.org/id/ENSGALT00010067341.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041199.1", "url": "https://www.ensembl.org/id/ENSGALP00010041199.1" } ] } }, { "isoform_ac": "A0A8V1ADA4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFW1/entry#A0A8V1ADA4-1", "sequence": { "sequence": "MHSLSEVEENFNPHACNGLWNQGGHPAGGQSCSGRAEIAEKRAAFLHSCAAGAALSYTGKRQAEICLHQISQNKVAVLLLAGGQGTRLGVSYPKGMYNVGLPSGKTLYQIQAERIRKVEQLAGQRHHCKCTIPWYIMTSEFTLGPTEEFFVKHSYFNLDKANVIMFEQRMLPAVTFDGKAILEEKGKIAMAPDGNGGLYRALVDNKILDDMKQRGIQYVHVYCVDNILVKMADPVFIGFCVAKGADCGAKVVEKAYPTEPIGVVCRVDGVSHVVVEYSEISPETAQQRRPDGGLMYSVGNICNHFFTVEFLQTVAQKHESQLKHHVAIKKVPYIDEEGNLVKPLKPNGIKLEKFVFDVFQFSKNFVAFEVLREEEFSPLKNADTAETDNPTTARQSLLAQHYRWALKAGARFLDEDGCRIPEKLSLSGTEDPPAVCEISPLVSYFGEGLEAYMKNKDFCSPFILDEDKAEMLRSC", "length": 475, "header": "tr|A0A8V1ADA4-1|A0A8V1AFW1_CHICK Computationally mapped isoform of UDP-N-acetylglucosamine pyrophosphorylase 1 like 1 OS=Gallus gallus OX=9031 GN=UAP1L1 PE=1 SV=1 CANONICAL=A0A8V1AFW1-1" }, "locus": { "chromosome": "17", "start_pos": 1052144, "end_pos": 1031623, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067337.1", "url": "https://www.ensembl.org/id/ENSGALT00010067337.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041198.1", "url": "https://www.ensembl.org/id/ENSGALP00010041198.1" } ] } }, { "isoform_ac": "A0A8V1AFW1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFW1/entry#A0A8V1AFW1-1", "sequence": { "sequence": "MEPPEEVRARLERAGQGHLLRFWAELDPAQRAELLAALPPGLGEHCRLAAACARPRERLERLDGRVEPLPAAVLGSVRHCGPAALQRWEDEGLHQISQNKVAVLLLAGGQGTRLGVSYPKGMYNVGLPSGKTLYQIQAERIRKVEQLAGQRHHCKCTIPWYIMTSEFTLGPTEEFFVKHSYFNLDKANVIMFEQRMLPAVTFDGKAILEEKGKIAMAPDGNGGLYRALVDNKILDDMKQRGIQYVHVYCVDNILVKMADPVFIGFCVAKGADCGAKVVEKAYPTEPIGVVCRVDGVSHVVVEYSEISPETAQQRRPDGGLMYSVGNICNHFFTVEFLQTVAQKHESQLKHHVAIKKVPYIDEEGNLVKPLKPNGIKLEKFVFDVFQFSKNFVAFEVLREEEFSPLKNADTAETDNPTTARQSLLAQHYRWALKAGARFLDEDGCRIPEKLSLSGTEDPPAVCEISPLVSYFGEGLEAYMKNKDFCSPFILDEDKAEMLRSC", "length": 501, "header": "tr|A0A8V1AFW1-1|A0A8V1AFW1_CHICK Isoform 1 of UDP-N-acetylglucosamine pyrophosphorylase 1 like 1 OS=Gallus gallus OX=9031 GN=UAP1L1 PE=1 SV=1 CANONICAL=A0A8V1AFW1-1" }, "locus": { "chromosome": "17", "start_pos": 1046922, "end_pos": 1031623, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067336.1", "url": "https://www.ensembl.org/id/ENSGALT00010067336.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041197.1", "url": "https://www.ensembl.org/id/ENSGALP00010041197.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:417295", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417295", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287AAG0-1", "protein_name": "UDP-N-acetylhexosamine pyrophosphorylase-like protein 1", "gene_name": "UAP1L1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTSERDVRARLQRAGQEHLLRFCAELAPGPRAALLAQLEPLEPEALREHCRRAADACARPPGPPPDLAARLRPLPPERVGSAIGGDPETLRLWEEEGFHQIALNKVAVLLLAGGQGTRLGVAYPKGMYQVGLPSRKTLYQLQAERIRRVEQLAGEHYGTRCTVPWYIMTSEFTLGPTAKFFKEHDFFHLDPDNVVMFEQRMLPAVTFDGKAILEQKDKVAMAPDGNGGLYCALADNQILEDMERRGVEFVHVYCVDNILVRLADPVFIGFCVLRGADCGAKVVEKAYPEEPVGVVCQVDGVPQVVEYSEISPETARRRAPGGGLLYNAGNICNHFFTRDFLQRVTRELEPLLKPHVAVKKVPYVDEEGTPVKPLEPNGIKMEKFVFDVLPFAKNFVAFQVLREDEFSPLKNADSADRDNPSTARRALLTQHYRWALQAGAHFLDAHGARLPEKPSLPSSGEPPAICEISPLVSYSGEGLEVYLQGREFGSPLILDENQARALKP", "length": 504 }, "evidence": [ { "id": "A0A8V1AFW1", "url": "https://omabrowser.org/oma/group/A0A8V1AFW1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A3L7HDH6-1", "protein_name": "UDP-N-acetylhexosamine pyrophosphorylase-like protein 1", "gene_name": "Uap1l1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MASEQDVRAQLQRAGQEHLLRFWADLAPEPLAALLAELATLEPDALREHCQRAAAACALTPGPLADLAARLQPLPPECVGSAIRCDQETRLRWEEEGFRQIALNKVAVLLLAGGQGTRLGVTYPKGMYQVGLPSQKTLYQLQAERIRRVQQLAGQRLGTHCTVPWYIMTSEFTLGPTIKFFKEHDFFHLDPANVVLFEQRMLPAVTFEGKAILERKDKVAMAPDGNGGLYCALADHQILEDMKRRGVEFVHVYCVDNILVRLADPVFIGFCVLRGADCGAKVVEKAYPEEPVGVVCQVDGVPQVVEYSEISPETAGLRGPDGGLLYNTGNICNHFFTRDFLDKVTREFEPLLKLHVAVKKVPYVDEEGNLVKPLKPNGIKMEKFVFDVFQFAKNFVAFEVSREEEFSPLKNADTASRDNPSTSRRALLAQHYRWALQAGAHFLDVHGVQLPQQSGLLPNGDPPAICEISPLVSYSGEGLEMYLQGRKLQSPFILDEDQARLLQPQEC", "length": 507 }, "evidence": [ { "id": "A0A8V1AFW1", "url": "https://omabrowser.org/oma/group/A0A8V1AFW1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "O64765-1", "protein_name": "UDP-N-acetylglucosamine diphosphorylase 2", "gene_name": "GLCNAC1PUT2", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MKEPTTEIEIETSAVATILPPPLPPTASPHQALVERLKDYGQEDVFSLWDELSPEERDLLLRDIENLDLPRIDRIIRCSLHSQGLPVAAIEPVPENCVSTVEERTKEDREKWWKMGLKAIYEGKLGVVLLSGGQGTRLGSSDPKGCYNIGLPSGKSLFQIQAERILCVQRLASQAMSEASPTRPVTIQWYIMTSPFTHEPTQKFFKSHKYFGLEPDQVTFFQQGTLPCISKDGKFIMETPFSLSKAPDGNGGVYTALKSSRLLEDMASRGIKYVDCYGVDNVLVRVADPTFLGYFIDKSAASAAKVVRKAYPQEKVGVFVRRGKGGPLTVVEYTELDQSMASATNQQTGRLQYCWSNVCLHMFTLDFLNQVANGLEKDSVYHLAEKKIPSINGDIVGLKLEQFIFDCFPYAPSTALFEVLREEEFAPVKNANGSNYDTPESARLLVLRLHTRWVIAAGGFLTHSVPLYATGVEVSPLCSYAGENLEAICRGRTFHAPCEISL", "length": 502 }, "evidence": [ { "id": "A0A8V1AFW1", "url": "https://omabrowser.org/oma/group/A0A8V1AFW1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q3KQV9-1", "protein_name": "UDP-N-acetylhexosamine pyrophosphorylase-like protein 1", "gene_name": "UAP1L1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASEQDVRARLQRAGQEHLLRFWAELAPEPRAALLAELALLEPEALREHCRRAAEACARPHGPPPDLAARLRPLPPERVGRASRSDPETRRRWEEEGFRQISLNKVAVLLLAGGQGTRLGVTYPKGMYRVGLPSRKTLYQLQAERIRRVEQLAGERHGTRCTVPWYVMTSEFTLGPTAEFFREHNFFHLDPANVVMFEQRLLPAVTFDGKVILERKDKVAMAPDGNGGLYCALEDHKILEDMERRGVEFVHVYCVDNILVRLADPVFIGFCVLQGADCGAKVVEKAYPEEPVGVVCQVDGVPQVVEYSEISPETAQLRASDGSLLYNAGNICNHFFTRGFLKAVTREFEPLLKPHVAVKKVPYVDEEGNLVKPLKPNGIKMEKFVFDVFRFAKNFAALEVLREEEFSPLKNAEPADRDSPRTARQALLTQHYRWALRAGARFLDAHGAWLPELPSLPPNGDPPAICEISPLVSYSGEGLEVYLQGREFQSPLILDEDQAREPQLQES", "length": 507 }, "evidence": [ { "id": "A0A8V1AFW1", "url": "https://omabrowser.org/oma/group/A0A8V1AFW1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q3TW96-1", "protein_name": "UDP-N-acetylhexosamine pyrophosphorylase-like protein 1", "gene_name": "Uap1l1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDSERDVRAQLQRAGQDHLLRFYADLAPEARAALLAELASLEADALREHCQRAAAAGALAPGPLPDLAARLQPLPPERVGSAIRCDQETRLRWEEEGFRQISLNKVAVLLLAGGQGTRLGVTYPKGMYQVGLPSQKTLYQLQAERIRRVQQLADQRQGTHCTVPWYIMTSEFTLGPTIKFFKEHDFFHLDPTNVVLFEQRMLPAVTFEGKAILERKDKVAMAPDGNGGLYCALADHQILEDMKQRGVEFVHVYCVDNILVRLADPVFIGFCVLQGADCGAKVVEKAYPEEPVGVVCQVDGVPQVVEYSEISPEIAGQLGADGGLLYNAGNICNHFFTRGFLDVVTREFEPLLRLHVAMKKVPYVDEEGNLVKPLRPNGIKMEKFVFDVFQFAKNFVAFEVCREEEFSPLKNDDTADRDNPSTCRRALLAQHYRWALQAGARFLDVHGVQLTEQSGMLPNGDPPAICEISPLVSYSGEGLEMYLQGRQLQSPFILDEDQARLLRPQDC", "length": 507 }, "evidence": [ { "id": "A0A8V1AFW1", "url": "https://omabrowser.org/oma/group/A0A8V1AFW1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "uridylyltransferase activity", "id": "GO:0070569", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070569", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFW1", "url": 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computational analysis. This record is derived from a genomic sequence (NC_052556.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. 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acids regulate mTORC1" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A1B0GWT7-1", "protein_name": "Late endosomal/lysosomal adaptor, MAPK and MTOR activator 2", "gene_name": "Lamtor2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "PESGASSQPHSAPPCRRPAARQPAQLLLLLLLLARPARLGSGASNSPSRPSPRLRRPLRTAAATAPRAAWGGTAVGAARARAGCAAGPGRIVRPAQRAGDSGPPAVPSRLDKGLSVSPSHLRSPRLLNNEGSLLAYSGYGDTDARVTAAIASNIWAAYDRNGNQAFNEDSLKFILMDCMDQRNPGEGRNQGCQAECPSVLCHSHQEGRVAITRVANLLLCMYAKETVGFGMLKAKAQALVQYLEEPLTQVAAS", "length": 253 }, "evidence": [ { "id": "A0A8V1AEX1", "url": "https://omabrowser.org/oma/group/A0A8V1AEX1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F2Z518-1", "protein_name": "Ragulator complex protein LAMTOR2", "gene_name": "LAMTOR2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": 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"sequence": "MLRPKALTQVLSQANTGGVQSTLLLNNEGSLLAYSGYGDTDARVTAAIASNIWAAYDRNGNQAFNEDNLKFILMDCMEGRVAITRVANLLLCMYAKETVGFGMLKAKAQALVQYLEEPLTQVAAS", "length": 125 }, "evidence": [ { "id": "A0A8V1AEX1", "url": "https://omabrowser.org/oma/group/A0A8V1AEX1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q54F59-1", "protein_name": "Roadblock/LAMTOR2 domain-containing protein", "gene_name": "mapbpip", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MLRSKILPQILNQAINNTDTKGVLLMKDDGSLIACSDATTSSHNTSKIVAAITSNIWTAYNRNSDLQYQLIDCEEGRFVITRVASLLLCVYSDINTEFGLLKLKTQKLREYLEEPLSKVEHVQ", "length": 123 }, "evidence": [ { "id": "A0A8V1AEX1", "url": "https://omabrowser.org/oma/group/A0A8V1AEX1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q6DEG4-1", "protein_name": "Ragulator complex protein LAMTOR2", "gene_name": "lamtor2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLRPKALTQVLSQANTSGVQSTLLLNNEGSLLTYSGYGDTDARVTAAIASNIWAAYDKNGHQAFNEDKLKFILMDCMEGRVAITRVANLLLCMYAKETVGFGMLKAKAEALVQYLEEPLTQVAAS", "length": 125 }, "evidence": [ { "id": "A0A8V1AEX1", "url": "https://omabrowser.org/oma/group/A0A8V1AEX1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q9JHS3-1", "protein_name": "Ragulator complex protein LAMTOR2", "gene_name": "Lamtor2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLRPKALTQVLSQANTGGVQSTLLLNNEGSLLAYSGYGDTDARVTAAIASNIWAAYDRNGNQAFNEDSLKFILMDCMEGRVAITRVANLLLCMYAKETVGFGMLKAKAQALVQYLEEPLTQVAAS", "length": 125 }, "evidence": [ { "id": "A0A8V1AEX1", "url": "https://omabrowser.org/oma/group/A0A8V1AEX1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9V8I2-1", "protein_name": "Ragulator complex protein LAMTOR2 homolog", "gene_name": "Lamtor2", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MLKPKALTQVLSQANTGGVENTLLLSQEGALLAYSGYGDKDARITAAIASNIWAAYEKHGRNAFREGRLTFVLIDCENGHVAITQVASVLLCLYAKQTVGLGLLKQKAMSLASYLERPLKQISAS", "length": 125 }, "evidence": [ { "id": "A0A8V1AEX1", "url": "https://omabrowser.org/oma/group/A0A8V1AEX1/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9Y2Q5-1", "protein_name": "Ragulator complex protein LAMTOR2", "gene_name": "LAMTOR2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLRPKALTQVLSQANTGGVQSTLLLNNEGSLLAYSGYGDTDARVTAAIASNIWAAYDRNGNQAFNEDNLKFILMDCMEGRVAITRVANLLLCMYAKETVGFGMLKAKAQALVQYLEEPLTQVAAS", "length": 125 }, "evidence": [ { "id": "A0A8V1AEX1", "url": "https://omabrowser.org/oma/group/A0A8V1AEX1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "positive regulation of TORC1 signaling", "id": "GO:1904263", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904263", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEX1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEX1" } ], "pmid": "" }, { "name": "regulation of cell growth", "id": "GO:0001558", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001558", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEX1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEX1" } ], "pmid": "" }, { "name": "positive regulation of TOR signaling", "id": "GO:0032008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032008", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEX1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEX1" } ], "pmid": "" }, { "name": "intracellular protein localization", "id": "GO:0008104", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008104", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEX1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEX1" } ], "pmid": "" }, { "name": "cellular response to amino acid stimulus", "id": "GO:0071230", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071230", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEX1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEX1" } ], "pmid": "" }, { "name": "regulation of cell-substrate junction organization", "id": "GO:0150116", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0150116", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEX1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEX1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "molecular adaptor activity", "id": "GO:0060090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060090", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEX1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEX1" } ], "pmid": "" }, { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEX1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEX1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "lysosomal membrane", "id": "GO:0005765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005765", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEX1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEX1" } ], "pmid": "" }, { "name": "late endosome membrane", "id": "GO:0031902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031902", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEX1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEX1" } ], "pmid": "" }, { "name": "Ragulator complex", "id": "GO:0071986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071986", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEX1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEX1" } ], "pmid": "" }, { "name": "FNIP-folliculin RagC/D GAP", "id": "GO:1990877", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990877", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEX1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEX1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AEX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEX1" }, { "id": "SM00960", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00960" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Roadblock/LAMTOR2", "eco_id": "ECO_0000259", "start_pos": 7, "end_pos": 95, "start_aa": "Leu", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AF04-1", "uniprot_ac": "A0A8V1AF04", "uniprot_id": "A0A8V1AF04_CHICK", "mass": { "chemical_mass": 44735.0, "monoisotopic_mass": 44735.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "G-protein coupled receptors family 1 profile domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8V1AF04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF04/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AF04", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF04" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF04", "locus": {} } ], "crossref": [ { "id": "A0A8V1AF04", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AF04", "database": "AlphaFoldDB", "categories": [] }, { "id": "PTHR47202", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47202", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47202:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47202:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A7A3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7A3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A7A3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7A3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AF04", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF04", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AF04-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF04-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "IALSSTALCCTVLHCHCTVLHCAVLCCVALHCTVWHCTVLHCVALHCAVLCCIALHCVALCCVALLHCTHCTVLHCVALRCAVLCCIALHCVALHCVALRCAVLCCIALHCVALHCVALCCIALCCAVLHCIALCSTVLCCTVLHCTVLCCVALHCVALRCVALCCIHCAVLYCVALHCAVLCCIALCSTALCCTVLHCIAWCCFALPCFTLHCALWCYTVLHCVALCCAVLHCIVLCCVALWCVVLHCVMLHSVVLCCSALHCPALCFATRCCVALLHCTVLCCVALCCTALLHCIALCSVALLCAVLHYVVLYCAVALCCTVLCCTAWYCTLLHCVALCCIALHCTSLLCVALCCIALRCTALLCVALPCVALHCSVLLCVALPCVAPHCSVLLCVALPCVAPLCSVLQWAHGSTYSTASSR", "length": 424, "header": "tr|A0A8V1AF04-1|A0A8V1AF04_CHICK Isoform 1 of G-protein coupled receptors family 1 profile domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1AF04-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A7A3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF04/entry#A0A8V1A7A3-1", "sequence": { "sequence": "LPSSSTKYVGLGRSGRSCGERRGAAPLRSELRGAPPRCAALCCVGLHCTVLFCTALLCVALCCAVLHCIVLHCVALCCVALCCIALCCVALHSLHCVALRCAVLCCIALHCVALHCVALRSLRCVALRCAVLCCIALHCVALCCVALCCIALCCVALHCIALCSTVLCCTLLHCAVLCCIALHCVALCCVALLHCTHCTVLHCVALRCAVLCCIALHCVALHCVALRCAVLCCIALHCVALHCVALCCIALCCAVLHCIALCSTVLCCTVALHCAVLCCIALHCVALHCVALCCIALCCAVLHCIALCSTALCCIALCCAVLHCIALCGTALCCTVLHCTVLCCVALHCTV", "length": 351, "header": "tr|A0A8V1A7A3-1|A0A8V1AF04_CHICK Computationally mapped isoform of G-protein coupled receptors family 1 profile domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1AF04-1" }, "locus": { "chromosome": "25", "start_pos": 433017, "end_pos": 430763, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068076.1", "url": "https://www.ensembl.org/id/ENSGALT00010068076.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041819.1", "url": "https://www.ensembl.org/id/ENSGALP00010041819.1" } ] } }, { "isoform_ac": "A0A8V1AF04-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF04/entry#A0A8V1AF04-1", "sequence": { "sequence": "IALSSTALCCTVLHCHCTVLHCAVLCCVALHCTVWHCTVLHCVALHCAVLCCIALHCVALCCVALLHCTHCTVLHCVALRCAVLCCIALHCVALHCVALRCAVLCCIALHCVALHCVALCCIALCCAVLHCIALCSTVLCCTVLHCTVLCCVALHCVALRCVALCCIHCAVLYCVALHCAVLCCIALCSTALCCTVLHCIAWCCFALPCFTLHCALWCYTVLHCVALCCAVLHCIVLCCVALWCVVLHCVMLHSVVLCCSALHCPALCFATRCCVALLHCTVLCCVALCCTALLHCIALCSVALLCAVLHYVVLYCAVALCCTVLCCTAWYCTLLHCVALCCIALHCTSLLCVALCCIALRCTALLCVALPCVALHCSVLLCVALPCVAPHCSVLLCVALPCVAPLCSVLQWAHGSTYSTASSR", "length": 424, "header": "tr|A0A8V1AF04-1|A0A8V1AF04_CHICK Isoform 1 of G-protein coupled receptors family 1 profile domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1AF04-1" }, "locus": { "chromosome": "25", "start_pos": 433921, "end_pos": 432086, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068075.1", "url": "https://www.ensembl.org/id/ENSGALT00010068075.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041818.1", "url": "https://www.ensembl.org/id/ENSGALP00010041818.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 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"uniprot_ac": "A0A8V1AF13", "uniprot_id": "A0A8V1AF13_CHICK", "mass": { "chemical_mass": 31858.0, "monoisotopic_mass": 31858.0 }, "refseq": {}, "gene_names": [ { "name": "XRCC2", "type": "recommended", "evidence": [ { "id": "A0A8V1AF13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF13" } ] } ], "protein_names": [ { "name": "X-ray repair cross complementing 2", "type": "synonym", "evidence": [ { "id": "A0A8V1AF13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF13/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AF13", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF13" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "XRCC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF13", "locus": { "chromosome": "2", "start_pos": 6785626, "end_pos": 6798174, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027158", "url": "https://www.ensembl.org/id/ENSGALG00010027158" } ] } } ], "crossref": [ { "id": "A0A8V1AF13", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AF13", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd19490", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19490", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "420438", "url": "https://www.ncbi.nlm.nih.gov/gene/420438", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013632", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013632", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020588", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020588", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030547", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030547", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "THRIFFS", "url": "https://omabrowser.org/oma/group/THRIFFS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A7K1", "url": "https://www.orthodb.org/?gene=A0A8V1A7K1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ACZ5", "url": "https://www.orthodb.org/?gene=A0A8V1ACZ5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AF13", "url": "https://www.orthodb.org/?gene=A0A8V1AF13", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46644", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46644", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46644:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46644:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08423", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08423", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-5685942", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5685942", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5693537", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5693537", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5693568", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5693568", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5693579", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5693579", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5693616", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5693616", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1A7K1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7K1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A7K1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7K1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ACZ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACZ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ACZ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACZ5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AF13", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF13", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AF13-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF13-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MALLFLVLWQQAEELLARLEGRSSLKNLEPNLFAEEGSPVHGDVIEFHGPEGTGKTEMLYHLVARCIIPKSGGGLEVEVMFIDTDYHFDMLRLVTILEHRLEQSTEEMMKRCLGRLFLVNCNSSTQLLLTLYSLENMFCTHPSLCLLILDSISAFYWIDRSNGGESLNSQEMNLKKCANFLEKLVREHHLVLFATTQSIMQKSTNSAEGFFPLKLQSEIDADYRPYLCKSWQQMVTHRIFFSKQFNSGNSTGFTLVSCHLKKKHVAKRSFSIAECGVQF", "length": 279, "header": "tr|A0A8V1AF13-1|A0A8V1AF13_CHICK Isoform 1 of X-ray repair cross complementing 2 OS=Gallus gallus OX=9031 GN=XRCC2 PE=4 SV=1 CANONICAL=A0A8V1AF13-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A7K1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF13/entry#A0A8V1A7K1-1", "sequence": { "sequence": "MVESYSSDLLARLEGRSSLKNLEPNLFAEEGSPVHGDVIEFHGPEGTGKTEMLYHLVARCIIPKSGGGLEVEVMFIDTDYHFDMLRLVTILEHRLEQSTEEMMKRCLGRLFLVNCNSSTQLLLTLYSLENMFCTHPSLCLLILDSISAFYWIDRSNGGESLNSQEMNLKKCANFLEKLVREHHLVLFATTQSIMQKSTNSAEGFFPLKLQSEIDADYRPYLCKSWQQMVTHRIFFSKQFNSGNSTGFTLVSCHLKKKHVAKRSFSIAECGVQF", "length": 273, "header": "tr|A0A8V1A7K1-1|A0A8V1AF13_CHICK Computationally mapped isoform of X-ray repair cross complementing 2 OS=Gallus gallus OX=9031 GN=XRCC2 PE=4 SV=1 CANONICAL=A0A8V1AF13-1" }, "locus": { "chromosome": "2", "start_pos": 6797566, "end_pos": 6787929, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065846.1", "url": "https://www.ensembl.org/id/ENSGALT00010065846.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040112.1", "url": "https://www.ensembl.org/id/ENSGALP00010040112.1" } ] } }, { "isoform_ac": "A0A8V1ACZ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF13/entry#A0A8V1ACZ5-1", "sequence": { "sequence": "MGDAFRRAESGTQLLARLEGRSSLKNLEPNLFAEEGSPVHGDVIEFHGPEGTGKTEMLYHLVARCIIPKSGGGLEVEVMFIDTDYHFDMLRLVTILEHRLEQSTEEMMKRCLGRLFLVNCNSSTQLLLTLYSLENMFCTHPSLCLLILDSISAFYWIDRSNGGESLNSQEMNLKKCANFLEKLVREHHLVLFATTQSIMQKSTNSAEGFFPLKLQSEIDADYRPYLCKSWQQMVTHRIFFSKQFNSGNSTGFTLVSCHLKKKHVAKRSFSIAECGVQF", "length": 278, "header": "tr|A0A8V1ACZ5-1|A0A8V1AF13_CHICK Computationally mapped isoform of X-ray repair cross complementing 2 OS=Gallus gallus OX=9031 GN=XRCC2 PE=4 SV=1 CANONICAL=A0A8V1AF13-1" }, "locus": { "chromosome": "2", "start_pos": 6798114, "end_pos": 6787929, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065847.1", "url": "https://www.ensembl.org/id/ENSGALT00010065847.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040113.1", "url": "https://www.ensembl.org/id/ENSGALP00010040113.1" } ] } }, { "isoform_ac": "A0A8V1AF13-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF13/entry#A0A8V1AF13-1", "sequence": { "sequence": "MALLFLVLWQQAEELLARLEGRSSLKNLEPNLFAEEGSPVHGDVIEFHGPEGTGKTEMLYHLVARCIIPKSGGGLEVEVMFIDTDYHFDMLRLVTILEHRLEQSTEEMMKRCLGRLFLVNCNSSTQLLLTLYSLENMFCTHPSLCLLILDSISAFYWIDRSNGGESLNSQEMNLKKCANFLEKLVREHHLVLFATTQSIMQKSTNSAEGFFPLKLQSEIDADYRPYLCKSWQQMVTHRIFFSKQFNSGNSTGFTLVSCHLKKKHVAKRSFSIAECGVQF", "length": 279, "header": "tr|A0A8V1AF13-1|A0A8V1AF13_CHICK Isoform 1 of X-ray repair cross complementing 2 OS=Gallus gallus OX=9031 GN=XRCC2 PE=4 SV=1 CANONICAL=A0A8V1AF13-1" }, "locus": { "chromosome": "2", "start_pos": 6795706, "end_pos": 6787929, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065845.1", "url": "https://www.ensembl.org/id/ENSGALT00010065845.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040111.1", "url": "https://www.ensembl.org/id/ENSGALP00010040111.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-5685942", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5685942", "resource": "Reactome", "description": "HDR through Homologous Recombination (HRR)" }, { "id": "R-GGA-5693537", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5693537", "resource": "Reactome", "description": "Resolution of D-Loop Structures" }, { "id": "R-GGA-5693568", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5693568", "resource": "Reactome", "description": "Resolution of D-loop Structures through Holliday Junction Intermediates" }, { "id": "R-GGA-5693579", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5693579", "resource": "Reactome", "description": "Homologous DNA Pairing and Strand Exchange" }, { "id": "R-GGA-5693616", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5693616", "resource": "Reactome", "description": "Presynaptic phase of homologous DNA pairing and strand exchange" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287B280-1", "protein_name": "X-ray repair cross complementing 2", "gene_name": "XRCC2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MCSDFHRAESGTELLARLEGRSSLREIEPCLFADEDSPVHGDILEFHGPEGTGKTEMLYHLTARCILPKAEGGLEVEVLFIDTDYHFDMLRLVTVLEHRLSQSSEEIMKYCLGRLFLVYCSSSTQLLLTLYSLETLFCSHPSVCVLIVDSLSAFYWIDRVNGGESINLQESTLKKCSQLLEKLVSEYRLVLFATTQSIMQKTSNAAEEPSCAFRRPGDGDIDYRPYLCRAWQQVVKHRVFFSKHEDPNTSSRFSLVSRHLKSNSFKKLFFIIGESGVEFC", "length": 280 }, "evidence": [ { "id": "A0A8V1AF13", "url": "https://omabrowser.org/oma/group/A0A8V1AF13/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "D3ZPC8-1", "protein_name": "X-ray repair cross complementing 2", "gene_name": "Xrcc2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MCSDFRRAESGTELLARLEGRSSLKELEPSLFADEDSPVHGDILEFHGPEGTGKTEMLYHLTARCILPKSEGGLQIEVLFIDTDYHFDMLRLVTVLEHRLSQSSEEAIKLCLGRLFLAYCSSSMQLLLTLYSLEALLCSHPSLCLLIVDSMSSFYWIDRVSGGESVSLQESTLQKCSQLLERLVTEYRLLLFATTQSLLQKGSDSAEGPSSSKHPCDGDMDYRAYLCKAWQRVVKHRVVFSREDEAKSSRFALVSRHLKSNSLKKHVFMIRESGVEFC", "length": 278 }, "evidence": [ { "id": "A0A8V1AF13", "url": "https://omabrowser.org/oma/group/A0A8V1AF13/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O43543-1", "protein_name": "DNA repair protein XRCC2", "gene_name": "XRCC2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MCSAFHRAESGTELLARLEGRSSLKEIEPNLFADEDSPVHGDILEFHGPEGTGKTEMLYHLTARCILPKSEGGLEVEVLFIDTDYHFDMLRLVTILEHRLSQSSEEIIKYCLGRFFLVYCSSSTHLLLTLYSLESMFCSHPSLCLLILDSLSAFYWIDRVNGGESVNLQESTLRKCSQCLEKLVNDYRLVLFATTQTIMQKASSSSEEPSHASRRLCDVDIDYRPYLCKAWQQLVKHRMFFSKQDDSQSSNQFSLVSRCLKSNSLKKHFFIIGESGVEFC", "length": 280 }, "evidence": [ { "id": "A0A8V1AF13", "url": "https://omabrowser.org/oma/group/A0A8V1AF13/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q682D3-1", "protein_name": "DNA repair protein XRCC2 homolog", "gene_name": "XRCC2", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MGDDEARSWIRGDETAKQMLSRVLKDRAFLLIPPLHRVPLRAGNVVEITGASTSAKTQILIQAAISCILPKTWNGIHYGGLGKLVLFLDLDCRFDVLRLSQMLKHRLLQANWLGNGAWWQLEESNVKSCKSAEEKTKTVFDEELYASCMKRFLYVRCYDSLELLSSLKTLHYRIQQQEACGSQVGVLMIDSIGAFHWTDRLSSSLALETHNRKSLSLTNVVETIVQELKKLLLVHSLVVLATKGTIYEEKYPANENNRKVSSNDHFSGNVASKAQQPPFREFMPSSWQAFVTHKIIIRKSADYQSLQTGQQNLLAYSLEWLQPQLSRIDRFIVDDVRKLTTIKPFYSKLLLIYIVIPASSSHAVWYCHCLVT", "length": 372 }, "evidence": [ { "id": "A0A8V1AF13", "url": "https://omabrowser.org/oma/group/A0A8V1AF13/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9CX47-1", "protein_name": "DNA repair protein XRCC2", "gene_name": "Xrcc2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MCSDFRRAESGTELLARLEGRSSLKELEPNLFADEDSPVHGDIFEFHGPEGTGKTEMLYHLTARCILPKSEGGLQIEVLFIDTDYHFDMLRLVTVLEHRLSQSSEEAMKLCLARLFLAYCSSSMQLLLTLHSLEALLCSRPSLCLLIVDSLSSFYWIDRVSGGESVALQESTLQKCSQLLERLVTEYRLLLFATTQSLMQKGSDSADGPSSSKHPCDGDMGYRAYLCKAWQRVVKHRVIFSRDDEAKSSRFSLVSRHLKSNSLKKHSFMVRESGVEFC", "length": 278 }, "evidence": [ { "id": "A0A8V1AF13", "url": "https://omabrowser.org/oma/group/A0A8V1AF13/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AF13", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF13" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AF13", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF13" } ], "pmid": "" }, { "name": "ATP-dependent DNA damage sensor activity", "id": "GO:0140664", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140664", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AF13", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF13" } ], "pmid": "" }, { "name": "four-way junction DNA binding", "id": "GO:0000400", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000400", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AF13", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF13" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "double-strand break repair via homologous recombination", "id": "GO:0000724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000724", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AF13", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF13" } ], "pmid": "" }, { "name": "mitotic cell cycle", "id": "GO:0000278", "url": 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"publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AFG7-1", "uniprot_ac": "A0A8V1AFG7", "uniprot_id": "A0A8V1AFG7_CHICK", "mass": { "chemical_mass": 61674.0, "monoisotopic_mass": 61674.0 }, "refseq": { "ac": "XP_025003158", "name": "zinc finger protein 467 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025003158" }, "gene_names": [ { "name": "ZNF467", "type": "recommended", "evidence": [ { "id": "A0A8V1AFG7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFG7" } ] }, { "name": "ZNF467", "type": "synonym", "evidence": [ { "id": "XP_025003158", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025003158" } ] } ], "protein_names": [ { "name": "Zinc finger protein 467", "type": "synonym", "evidence": [ { "id": "A0A8V1AFG7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFG7/entry#names_and_taxonomy" } ] }, { "name": "zinc finger protein 467 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_025003158", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025003158" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052533.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_025003158", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025003158" } ] }, { "annotation": "May be involved in transcriptional regulation.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A805", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A805#function" }, { "database": "UniProtKB", "id": "ARBA00003767", "url": "https://www.uniprot.org/uniprotkb/ARBA00003767#function" }, { "database": "UniProtKB", "id": "A0A8V1AFG7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFG7#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFG7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFG7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ZNF467", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFG7", "locus": {} } ], "crossref": [ { "id": "A0A8V1AFG7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AFG7", "database": "AlphaFoldDB", "categories": [] }, { "id": "107052491", "url": "https://www.ncbi.nlm.nih.gov/gene/107052491", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050688", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050688", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:107052491", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:107052491", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { 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"http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24403:SF107", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_025003158", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025003158", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1A805", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A805", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A805-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A805-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFG7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFG7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFG7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFG7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { 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"MRENFDALLALGVPIAKPEPVPQAEESCAGAQLEDGEAPGCAGSARLLVPKEEVLPEGDADGGGATGAAQGPELGCSEDWLVRKVKVEDEDEEWAAGLGAEALLAGQPPGSACKPEPTEEPELPGEPGELGYGTLPAFAWPLLGEGPAGACQHCCCAAQCGQCVPPAPAPPRPFACAQCGKGFGKKAHLTRHLRVHTGERPYPCAQCGRRFRQKIHLRSHQKTHTGERPFPCSECGRRFRKKTHLVRHLRTHTGERPFACALCGRGFAHKQHLLRHQRLHAEPPADAEPPADEKPFPCPECGKSFSWKKNLTSHRRLHLEGRPFACAECGRGFSDKRHLTAHLRGHMGLKPYACPHCDKTFSHKPNLATHQRTHTGERPFACPDCGRGFAHNQHLLRHLRVHTGERPFACPQCGRCFSSRPNLIAHTKAHAGARPFTCEQCGRGFSRKSHLARHQAVHTGTRPYGCSQCAKRFSSKTNLVRHQAVHTGHRPYICTQCGKSFSRKTHLLRHERTHSTAPAPRQGWVAPAPAPATLCP", "length": 536, "header": "tr|A0A8V1A805-1|A0A8V1AFG7_CHICK Computationally mapped isoform of Zinc finger protein 467 OS=Gallus gallus OX=9031 GN=ZNF467 PE=3 SV=1 CANONICAL=A0A8V1AFG7-1" }, "locus": { "chromosome": "2", "start_pos": 454556, "end_pos": 452583, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066009.1", "url": "https://www.ensembl.org/id/ENSGALT00010066009.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040275.1", "url": "https://www.ensembl.org/id/ENSGALP00010040275.1" } ] } }, { "isoform_ac": "A0A8V1AFG7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFG7/entry#A0A8V1AFG7-1", "sequence": { "sequence": "MRENFDALLALGVPIAKPEPVPQAEESCAGAQLEDGEAPGCAGSGGCRAVGERPSRAGVCAGPGRRTALGLTAYPPARLLVPKEEVLPEGDADGGGATGAAQGPELGCSEDWLVRKVKVEDEDEEWAAGLGAEALLAGQPPGSACKPEPTEEPELPGEPGELGYGTLPAFAWPLLGEGPAGACQHCCCAAQCGQCVPPAPAPPRPFACAQCGKGFGKKAHLTRHLRVHTGERPYPCAQCGRRFRQKIHLRSHQKTHTGERPFPCSECGRRFRKKTHLVRHLRTHTGERPFACALCGRGFAHKQHLLRHQRLHAEPPADAEPPADEKPFPCPECGKSFSWKKNLTSHRRLHLEGRPFACAECGRGFSDKRHLTAHLRGHMGLKPYACPHCDKTFSHKPNLATHQRTHTGERPFACPDCGRGFAHNQHLLRHLRVHTGERPFACPQCGRCFSSRPNLIAHTKAHAGARPFTCEQCGRGFSRKSHLARHQAVHTGTRPYGCSQCAKRFSSKTNLVRHQAVHTGHRPYICTQCGKSFSRKTHLLRHERTHSTAPAPRQGWVAPAPAPATLCP", "length": 568, "header": "tr|A0A8V1AFG7-1|A0A8V1AFG7_CHICK Isoform 1 of Zinc finger protein 467 OS=Gallus gallus OX=9031 GN=ZNF467 PE=3 SV=1 CANONICAL=A0A8V1AFG7-1" }, "locus": { "chromosome": "2", "start_pos": 454556, "end_pos": 452583, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066007.1", "url": "https://www.ensembl.org/id/ENSGALT00010066007.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040273.1", "url": "https://www.ensembl.org/id/ENSGALP00010040273.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:107052491", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:107052491", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFG7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFG7" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": 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Classification" ] }, { "id": "PTHR21425", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21425", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21425:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21425:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07406", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07406", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1A858", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A858", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A858-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A858-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFV5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFV5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFV5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFV5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AI50", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI50", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AI50-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI50-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAGAGSNWLSGVNVVLVMAYGSLVFVLLFIFVKRQIMRFAMKSRRGPHVPVGQHAPKDLKEEIDIRLSRVQDIKYEPQLLAEDDSRLLQLETQGDVPITAGTSVGLLSVRHIRGAAVSQAHPWGCCQAHPWGWARGRALAGPVGQLGVSLCSAQPSVWFLSFPGCYNYLYRMKALDAIRTSGEGQRGRSAGTKQGCIGQRLGSPSVIKPPHPPPPGLAVLSHWQQALIGGSRVGGGLMNEPRTFSFAVCFTQLCCTFCFPEIPFHAEGRYPKSLIGKNFCAYLLELRNSSSSFKGIRKALIDTLLDGYENARYGTGVFGKPEYLKYQDALNELANMTKARAGSSQRQHQSAAKDLTLSPEVSNPATIQVTYLPSSQKSKRAKHFLELKSFKDNYNTLESTL", "length": 401, "header": "tr|A0A8V1AFV5-1|A0A8V1AFV5_CHICK Isoform 1 of Lipid transport auxiliary protein 1 OS=Gallus gallus OX=9031 GN=C1orf43 PE=3 SV=1 CANONICAL=A0A8V1AFV5-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A858-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFV5/entry#A0A8V1A858-1", "sequence": { "sequence": "MAGAGSNWLSGVNVVLVMAYGSLVFVLLFIFVKRQIMRFAMKSRRGPHVPVGQHAPKDLKEEIDIRLSRVQDIKYEPQLLAEDDSRLLQLETQGDVPITAGTSVGLLSVRHIRGAAVSQAHPWGWARGRALAGPVGQLGVSLCSAQPSVWFLSFPGCYNYLYRMKALDAIRTSGEGQRGRSAGTKQGCIGQRLGSPSVIKPPHPPPPGLAVLSHWQQALIGGSRVGGGLMNEPRTFSFAVCFTQLCCTFCFPEIPFHAEGRYPKSLIGKNFCAYLLELRNSSSSFKGIRKALIDTLLDGYENARYGTGVFGKPEYLKYQDALNELANMTKARAGSSQRQHQSAAKDLTLSPEVSNPATIQVTYLPSSQKSKRAKHFLELKSFKDNYNTLESTL", "length": 393, "header": "tr|A0A8V1A858-1|A0A8V1AFV5_CHICK Computationally mapped isoform of Lipid transport auxiliary protein 1 OS=Gallus gallus OX=9031 GN=C1orf43 PE=3 SV=1 CANONICAL=A0A8V1AFV5-1" }, "locus": { "chromosome": "25", "start_pos": 1897522, "end_pos": 1894550, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068462.1", "url": "https://www.ensembl.org/id/ENSGALT00010068462.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042137.1", "url": "https://www.ensembl.org/id/ENSGALP00010042137.1" } ] } }, { "isoform_ac": "A0A8V1AFV5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFV5/entry#A0A8V1AFV5-1", "sequence": { "sequence": "MAGAGSNWLSGVNVVLVMAYGSLVFVLLFIFVKRQIMRFAMKSRRGPHVPVGQHAPKDLKEEIDIRLSRVQDIKYEPQLLAEDDSRLLQLETQGDVPITAGTSVGLLSVRHIRGAAVSQAHPWGCCQAHPWGWARGRALAGPVGQLGVSLCSAQPSVWFLSFPGCYNYLYRMKALDAIRTSGEGQRGRSAGTKQGCIGQRLGSPSVIKPPHPPPPGLAVLSHWQQALIGGSRVGGGLMNEPRTFSFAVCFTQLCCTFCFPEIPFHAEGRYPKSLIGKNFCAYLLELRNSSSSFKGIRKALIDTLLDGYENARYGTGVFGKPEYLKYQDALNELANMTKARAGSSQRQHQSAAKDLTLSPEVSNPATIQVTYLPSSQKSKRAKHFLELKSFKDNYNTLESTL", "length": 401, "header": "tr|A0A8V1AFV5-1|A0A8V1AFV5_CHICK Isoform 1 of Lipid transport auxiliary protein 1 OS=Gallus gallus OX=9031 GN=C1orf43 PE=3 SV=1 CANONICAL=A0A8V1AFV5-1" }, "locus": { "chromosome": "25", "start_pos": 1897522, "end_pos": 1894550, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068460.1", "url": "https://www.ensembl.org/id/ENSGALT00010068460.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042136.1", "url": "https://www.ensembl.org/id/ENSGALP00010042136.1" } ] } }, { "isoform_ac": "A0A8V1AI50-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFV5/entry#A0A8V1AI50-1", "sequence": { "sequence": "MAGAGSNWLSGVNVVLVMAYGSLVFVLLFIFVKRQIMRFAMKSRRGPHVPVGQHAPKDLKEEIDIRLSRVQDIKYEPQLLAEDDSRLLQLETQGCYNYLYRMKALDAIRTSEIPFHAEGRYPKSLIGKNFCAYLLELRNSSSSFKGIRKALIDTLLDGVFGKPEYLKYQDALNELANMTKARAGSSQRQHQSAAKDLTLSPEVSNPATIQVTYAFQPEEQTCQTLPGAEELQRQLQHVGEHAVSRDLPRAEPRAGHSKPGGGRGGFVLGWSSGALTVPLTGHRAGGALPPQEPLALLCPFWLPGMLRGARGRQPRPCE", "length": 318, "header": "tr|A0A8V1AI50-1|A0A8V1AFV5_CHICK Computationally mapped isoform of Lipid transport auxiliary protein 1 OS=Gallus gallus OX=9031 GN=C1orf43 PE=3 SV=1 CANONICAL=A0A8V1AFV5-1" }, "locus": { "chromosome": "25", "start_pos": 1897522, "end_pos": 1894323, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068459.1", "url": "https://www.ensembl.org/id/ENSGALT00010068459.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042135.1", "url": "https://www.ensembl.org/id/ENSGALP00010042135.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFV5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFV5" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFV5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFV5" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFV5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFV5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "phagocytosis", "id": "GO:0006909", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006909", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFV5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFV5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 288, "end_pos": 290, "annotation": "n_glycosylation_sequon" }, { "start_pos": 335, "end_pos": 337, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 288, "end_pos": 290 }, { "start_pos": 335, "end_pos": 337 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { 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"table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AFW9-1", "uniprot_ac": "A0A8V1AFW9", "uniprot_id": "A0A8V1AFW9_CHICK", "mass": { "chemical_mass": 9565.0, "monoisotopic_mass": 9565.0 }, "refseq": { "ac": "XP_040509540", "name": "cortexin-1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040509540" }, "gene_names": [ { "name": "CTXN1", "type": "recommended", "evidence": [ { "id": "A0A8V1AFW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFW9" } ] }, { "name": "CTXN1", "type": "synonym", "evidence": [ { "id": "XP_040509540", "database": "RefSeq", "url": 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This record is derived from a genomic sequence (NC_052559.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040509540", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040509540" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFW9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFW9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CTXN1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFW9", "locus": {} } ], "crossref": [ { "id": "A0A8V1AFW9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AFW9", "database": "AlphaFoldDB", "categories": [] }, { "id": "420051", "url": "https://www.ncbi.nlm.nih.gov/gene/420051", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR020066", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020066", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "AWTPDYE", "url": "https://omabrowser.org/oma/group/AWTPDYE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A873", "url": "https://www.orthodb.org/?gene=A0A8V1A873", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AFW9", "url": "https://www.orthodb.org/?gene=A0A8V1AFW9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16736", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16736", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16736:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16736:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF11057", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11057", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040509540", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040509540", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1A873", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A873", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A873-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A873-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFW9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFW9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFW9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFW9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNDASTMDYELLSPSLVEHPASTAGMDAEQKTVFAFVIFLLVFLVMLMVRCFRILLDPYSRMPASSWTDHKEGLERGQFDYALV", "length": 84, "header": "tr|A0A8V1AFW9-1|A0A8V1AFW9_CHICK Isoform 1 of Cortexin 1 OS=Gallus gallus OX=9031 GN=CTXN1 PE=4 SV=1 CANONICAL=A0A8V1AFW9-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A873-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFW9/entry#A0A8V1A873-1", "sequence": { "sequence": "IRATPRRTTRITRSPFLSTTPPWHPPLLPAAPRSSCSTTPTASPPPPCGSAALRGIAFPRIAPTPPTNPRTHTHTLPPHGSTFPRIPHNHRIPPAPREHRTAAPSARPPHPHVITSHPHCTPAPSTPSRPSYPNPFPPTPGPHPGASPLPALPLPPHPPEAQSGRVGRIQTPAPQSAGGGSAALHQPGRLRNGAGPDGLGEPRGGRGPLLPPGAQPKEAGSWRSLLSDVAVGRQPSASPAIAMLAHPHSWSELVCLTSAMNDASTMDYELLSPSLVEHPASTAGMDAEQKTVFAFVIFLLVFLVMLMVRCFRILLDPYSRMPASSWTDHKEGLERGQFDYALV", "length": 343, "header": "tr|A0A8V1A873-1|A0A8V1AFW9_CHICK Computationally mapped isoform of Cortexin 1 OS=Gallus gallus OX=9031 GN=CTXN1 PE=4 SV=1 CANONICAL=A0A8V1AFW9-1" }, "locus": { "chromosome": "28", "start_pos": 872322, "end_pos": 825059, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068527.1", "url": "https://www.ensembl.org/id/ENSGALT00010068527.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042152.1", "url": "https://www.ensembl.org/id/ENSGALP00010042152.1" } ] } }, { "isoform_ac": "A0A8V1AFW9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFW9/entry#A0A8V1AFW9-1", "sequence": { "sequence": "MNDASTMDYELLSPSLVEHPASTAGMDAEQKTVFAFVIFLLVFLVMLMVRCFRILLDPYSRMPASSWTDHKEGLERGQFDYALV", "length": 84, "header": "tr|A0A8V1AFW9-1|A0A8V1AFW9_CHICK Isoform 1 of Cortexin 1 OS=Gallus gallus OX=9031 GN=CTXN1 PE=4 SV=1 CANONICAL=A0A8V1AFW9-1" }, "locus": { "chromosome": "28", "start_pos": 825310, "end_pos": 825059, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068526.1", "url": "https://www.ensembl.org/id/ENSGALT00010068526.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042151.1", "url": "https://www.ensembl.org/id/ENSGALP00010042151.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A287ALM8-1", "protein_name": "Cortexin 1", "gene_name": "CTXN1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSATWTLSPEPLPPSTGPPVGAGLDAEQRTVFAFVLCLLVVLVLLMVRCVRILLDPYSRMPASSWTDHKEALERGQFDYALV", "length": 82 }, "evidence": [ { "id": "A0A8V1AFW9", "url": "https://omabrowser.org/oma/group/A0A8V1AFW9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A3L7HM83-1", "protein_name": "Cortexin-1", "gene_name": "LOC113835676", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MNAAWTLSPEPLPPSTGPPVGAGLDVEQRTVFAFVLCLLVVLVLLMVRCVRILLDPYSRMPASSWTDHKEALERGQFDYALV", "length": 82 }, "evidence": [ { "id": "A0A8V1AFW9", "url": "https://omabrowser.org/oma/group/A0A8V1AFW9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P60606-1", "protein_name": "Cortexin-1", "gene_name": "CTXN1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSATWTLSPEPLPPSTGPPVGAGLDAEQRTVFAFVLCLLVVLVLLMVRCVRILLDPYSRMPASSWTDHKEALERGQFDYALV", "length": 82 }, "evidence": [ { "id": "A0A8V1AFW9", "url": "https://omabrowser.org/oma/group/A0A8V1AFW9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8K129-1", "protein_name": "Cortexin-1", "gene_name": "Ctxn1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSAWTLSPEPLPPSTGPPVGAGLDVEQRTVFAFVLCLLVVLVLLMVRCVRILLDPYSRMPASSWTDHKEALERGQFDYALV", "length": 82 }, "evidence": [ { "id": "A0A8V1AFW9", "url": "https://omabrowser.org/oma/group/A0A8V1AFW9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFW9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFW9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AEW8-1", "uniprot_ac": "A0A8V1AEW8", "uniprot_id": "A0A8V1AEW8_CHICK", "mass": { "chemical_mass": 49195.0, "monoisotopic_mass": 49195.0 }, "refseq": {}, "gene_names": [ { "name": "PCBP4", "type": "recommended", "evidence": [ { "id": "A0A8V1AEW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEW8" } ] } ], "protein_names": [ { "name": "Poly(rC) binding protein 4", "type": "synonym", "evidence": [ { "id": "A0A8V1AEW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEW8/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEW8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEW8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PCBP4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEW8", "locus": { "chromosome": "12", "start_pos": 3324617, "end_pos": 3318027, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027548", "url": "https://www.ensembl.org/id/ENSGALG00010027548" } ] } } ], "crossref": [ { "id": "A0A8V1AEW8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AEW8", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd22517", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22517", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd22520", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22520", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd22523", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22523", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR004087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004088", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004088", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036612", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036612", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A9I5", "url": "https://www.orthodb.org/?gene=A0A8V1A9I5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AEW8", "url": "https://www.orthodb.org/?gene=A0A8V1AEW8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10288", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10288", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00013", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00013", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1A9I5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9I5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A9I5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9I5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AEW8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEW8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AEW8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEW8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGTRTSSWASSASATCGTWPATRCWCCRAPGTPATWTSPRSGTAGCWPSCSSWRTPHVPQAMASPDRASGPREPQLSITLTLRMLMHGKEIGSIIGKKGETVKRIREQSSARITISEGSCPERITTITGSTDAVFRAVSMIAFKLEEDLGDGTAAGRTPVTLRLVIPASQCGSLIGKAGTKIREIRESSGAQVQVAGDLLPNSTERAVTVSGVPDTIIQCVRQICAVILESPPKGATIPYHPGLSLGTILLSANQGFSMQGQYSGVPPAEVTKLQQMSGHTVPFPPLGHPPSMVPGLDSNSQSSSQEFLVPNDLIGCIIGRHGSKISEIRQMSGAHIKIGNQTEGSSERHITITGSPVSITLAQYLITTCLETAKSTSQVPLGPGSVDLGVGFSQPLAPGSGAALPAVPAAPPALLGTPYALSLSNFIGLKPLSFLALSPSSAAGANGGTATYTTKISAANGTKKADRQKFSPY", "length": 474, "header": "tr|A0A8V1AEW8-1|A0A8V1AEW8_CHICK Isoform 1 of Poly(rC) binding protein 4 OS=Gallus gallus OX=9031 GN=PCBP4 PE=4 SV=1 CANONICAL=A0A8V1AEW8-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A9I5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEW8/entry#A0A8V1A9I5-1", "sequence": { "sequence": "MASPDRASGPREPQLSITLTLRMLMHGKEIGSIIGKKGETVKRIREQSSARITISEGSCPERITTITGSTDAVFRAVSMIAFKLEEDLGDGTAAGRTPVTLRLVIPASQCGSLIGKAGTKIREIREVRSPGAHSVPQPVPPRSHSPSLPLPPPVFSPELGGSGAGGWRPAAQLHGARRHRLGGAGHHHPVCEADLCRHPGVASEGGHHPLPPRALPGHHPALCQPGKGHRGKGDPLIAWARVPVWFPADSHRPPSQGFSMQGQYSGVPPAEVTKLQQMSGHTVPFPPLGHPPSMVPGLDSNSQSSSQEFLVPNDLIGCIIGRHGSKISEIRQMSGAHIKIGNQTEGSSERHITITGSPVSITLAQYLITTW", "length": 371, "header": "tr|A0A8V1A9I5-1|A0A8V1AEW8_CHICK Computationally mapped isoform of Poly(rC) binding protein 4 OS=Gallus gallus OX=9031 GN=PCBP4 PE=4 SV=1 CANONICAL=A0A8V1AEW8-1" }, "locus": { "chromosome": "12", "start_pos": 3323613, "end_pos": 3320742, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066723.1", "url": "https://www.ensembl.org/id/ENSGALT00010066723.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040849.1", "url": "https://www.ensembl.org/id/ENSGALP00010040849.1" } ] } }, { "isoform_ac": "A0A8V1AEW8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEW8/entry#A0A8V1AEW8-1", "sequence": { "sequence": "MGTRTSSWASSASATCGTWPATRCWCCRAPGTPATWTSPRSGTAGCWPSCSSWRTPHVPQAMASPDRASGPREPQLSITLTLRMLMHGKEIGSIIGKKGETVKRIREQSSARITISEGSCPERITTITGSTDAVFRAVSMIAFKLEEDLGDGTAAGRTPVTLRLVIPASQCGSLIGKAGTKIREIRESSGAQVQVAGDLLPNSTERAVTVSGVPDTIIQCVRQICAVILESPPKGATIPYHPGLSLGTILLSANQGFSMQGQYSGVPPAEVTKLQQMSGHTVPFPPLGHPPSMVPGLDSNSQSSSQEFLVPNDLIGCIIGRHGSKISEIRQMSGAHIKIGNQTEGSSERHITITGSPVSITLAQYLITTCLETAKSTSQVPLGPGSVDLGVGFSQPLAPGSGAALPAVPAAPPALLGTPYALSLSNFIGLKPLSFLALSPSSAAGANGGTATYTTKISAANGTKKADRQKFSPY", "length": 474, "header": "tr|A0A8V1AEW8-1|A0A8V1AEW8_CHICK Isoform 1 of Poly(rC) binding protein 4 OS=Gallus gallus OX=9031 GN=PCBP4 PE=4 SV=1 CANONICAL=A0A8V1AEW8-1" }, "locus": { "chromosome": "12", "start_pos": 3324061, "end_pos": 3318748, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066725.1", "url": "https://www.ensembl.org/id/ENSGALT00010066725.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040850.1", "url": "https://www.ensembl.org/id/ENSGALP00010040850.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEW8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEW8" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEW8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEW8" } ], "pmid": "" }, { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEW8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEW8" } ], "pmid": "" }, { "name": "mRNA 3'-UTR binding", "id": "GO:0003730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003730", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEW8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEW8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEW8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEW8" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEW8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEW8" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEW8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEW8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEW8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEW8" } ], "pmid": "" }, { "name": "negative regulation of mRNA splicing, via spliceosome", "id": "GO:0048025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048025", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEW8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEW8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 202, "end_pos": 204, "annotation": "n_glycosylation_sequon" }, { "start_pos": 341, "end_pos": 343, "annotation": "n_glycosylation_sequon" }, { "start_pos": 461, "end_pos": 463, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AEW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEW8" }, { "id": "SM00322", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00322" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "K Homology", "eco_id": "ECO_0000259", "start_pos": 78, "end_pos": 146, "start_aa": "Ile", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 202, "end_pos": 204 }, { "start_pos": 341, "end_pos": 343 }, { "start_pos": 461, "end_pos": 463 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { 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"table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AF74-1", "uniprot_ac": "A0A8V1AF74", "uniprot_id": "A0A8V1AF74_CHICK", "mass": { "chemical_mass": 36599.0, "monoisotopic_mass": 36599.0 }, "refseq": { "ac": "XP_040508469", "name": "signaling lymphocytic activation molecule", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040508469" }, "gene_names": [ { "name": "SLAMF1", "type": "recommended", "evidence": [ { "id": "A0A8V1AF74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF74" } ] }, { "name": "SLAMF1", "type": "synonym", "evidence": [ { "id": "XP_040508469", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040508469" } ] } ], "protein_names": [ { "name": "Signaling lymphocytic activation molecule family member 1", "type": "synonym", "evidence": [ { "id": "A0A8V1AF74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF74/entry#names_and_taxonomy" } ] }, { "name": "signaling lymphocytic activation molecule", "type": "synonym", "evidence": [ { "id": "XP_040508469", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040508469" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052556.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040508469", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040508469" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AF74", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF74" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SLAMF1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF74", "locus": { "chromosome": "25", "start_pos": 1204910, "end_pos": 1199061, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027645", "url": "https://www.ensembl.org/id/ENSGALG00010027645" } ] } } ], "crossref": [ { "id": "A0A8V1AF74", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AF74", "database": "AlphaFoldDB", "categories": [] }, { "id": "425300", "url": "https://www.ncbi.nlm.nih.gov/gene/425300", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015631", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015631", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "DHVAYNW", "url": "https://omabrowser.org/oma/group/DHVAYNW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A9U4", "url": "https://www.orthodb.org/?gene=A0A8V1A9U4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ACK9", "url": "https://www.orthodb.org/?gene=A0A8V1ACK9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AF74", "url": "https://www.orthodb.org/?gene=A0A8V1AF74", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12080", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12080", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12080:SF55", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12080:SF55", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "XP_040508469", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040508469", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1A9U4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9U4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A9U4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9U4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ACK9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ACK9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AF74", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF74", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AF74-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF74-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGYSALFWLFISSCWVWGIGCRTVETVLGTLGKATVLGVPSEFQNLTQRSGTATWKRSMENPLSKEYLFTYNNGNYTNYKPGEILFHLSNFSLEILSTQRQDQQLYEYSITMEAHERNWQIQLEVYEPVSDPSIHILDWMLANDSCTVTLNCTVAQGDNVSYSWASSEASTSPLCTHNGSLLLLSYDPTNSILPCTCTASNPVSSRTTALRSSICSTEQQGSWRTGMLLLGVVLPIVILIVLAGVFTVAYVAANMRQPREQSPPTEDSTVHTIYSQVQRVEKPKSPCSPPGTDHPTCTTIYAAATGASLPPHSPQGANMEPMTVYASVMLPIS", "length": 333, "header": "tr|A0A8V1AF74-1|A0A8V1AF74_CHICK Isoform 1 of Signaling lymphocytic activation molecule family member 1 OS=Gallus gallus OX=9031 GN=SLAMF1 PE=4 SV=1 CANONICAL=A0A8V1AF74-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A9U4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF74/entry#A0A8V1A9U4-1", "sequence": { "sequence": "MGYSALFWLFISSCWVWGIGCRTVETVLGTLGKATVLGVPSEFQNLTQRSGTATWKRSMENPLSKEYLFTYNNGNYTNYKPGEILFHLSNFSLEILSTQRQDQQLYEYSITMEAHERNWQIQLEVYEPVSDPSIHILDWMLANDSCTVTLNCTVAQGDNVSYSWASSEASTSPLCTHNGSLLLLSYDPTNSILPCTCTASNPVSSRTTALRSSICSTEQQGQPREQSPPTEDSTVHTIYSQVQRVEKPKSPCSPPGTDHPTCTTIYAAATGASLPPHSPQGANMEPMTVYASVMLPIS", "length": 298, "header": "tr|A0A8V1A9U4-1|A0A8V1AF74_CHICK Computationally mapped isoform of Signaling lymphocytic activation molecule family member 1 OS=Gallus gallus OX=9031 GN=SLAMF1 PE=4 SV=1 CANONICAL=A0A8V1AF74-1" }, "locus": { "chromosome": "25", "start_pos": 1204018, "end_pos": 1199324, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066996.1", "url": "https://www.ensembl.org/id/ENSGALT00010066996.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040971.1", "url": "https://www.ensembl.org/id/ENSGALP00010040971.1" } ] } }, { "isoform_ac": "A0A8V1ACK9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF74/entry#A0A8V1ACK9-1", "sequence": { "sequence": "MGYSALFWLFISSCWVWGIGCRTVETVLGTLGKATVLGVPSEFQNLTQRSGTATWKRSMENPLSKEYLFTYNNGNYTNYKPGEILFHLSNFSLEILSTQRQDQQLYEYSITMEAHERNWQIQLEVYEPVSDPSIHILDWMLANDSCTVTLNCTVAQGDNVSYSWASSEASTSPLCTHNGSLLLLSYDPTNSILPCTCTASNPVSSRTTALRSSICSTEQQATGSWRTGMLLLGVVLPIVILIVLAGVFTVAYVAANMRQPREQSPPTEDSTVHTIYSQVQRVEKPKSPCSPPGTDHPTCTTIYAAATGASLPPHSPQVSGKGLRWVSH", "length": 328, "header": "tr|A0A8V1ACK9-1|A0A8V1AF74_CHICK Computationally mapped isoform of Signaling lymphocytic activation molecule family member 1 OS=Gallus gallus OX=9031 GN=SLAMF1 PE=4 SV=1 CANONICAL=A0A8V1AF74-1" }, "locus": { "chromosome": "25", "start_pos": 1203917, "end_pos": 1199324, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066999.1", "url": "https://www.ensembl.org/id/ENSGALT00010066999.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040973.1", "url": "https://www.ensembl.org/id/ENSGALP00010040973.1" } ] } }, { "isoform_ac": "A0A8V1AF74-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF74/entry#A0A8V1AF74-1", "sequence": { "sequence": "MGYSALFWLFISSCWVWGIGCRTVETVLGTLGKATVLGVPSEFQNLTQRSGTATWKRSMENPLSKEYLFTYNNGNYTNYKPGEILFHLSNFSLEILSTQRQDQQLYEYSITMEAHERNWQIQLEVYEPVSDPSIHILDWMLANDSCTVTLNCTVAQGDNVSYSWASSEASTSPLCTHNGSLLLLSYDPTNSILPCTCTASNPVSSRTTALRSSICSTEQQGSWRTGMLLLGVVLPIVILIVLAGVFTVAYVAANMRQPREQSPPTEDSTVHTIYSQVQRVEKPKSPCSPPGTDHPTCTTIYAAATGASLPPHSPQGANMEPMTVYASVMLPIS", "length": 333, "header": "tr|A0A8V1AF74-1|A0A8V1AF74_CHICK Isoform 1 of Signaling lymphocytic activation molecule family member 1 OS=Gallus gallus OX=9031 GN=SLAMF1 PE=4 SV=1 CANONICAL=A0A8V1AF74-1" }, "locus": { "chromosome": "25", "start_pos": 1204018, "end_pos": 1199324, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066998.1", "url": "https://www.ensembl.org/id/ENSGALT00010066998.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040972.1", "url": "https://www.ensembl.org/id/ENSGALP00010040972.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "D3ZAD7-1", "protein_name": "Signaling lymphocytic activation molecule family member 1", "gene_name": "Slamf1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDPNRSLSLRILLFLSLAVELSYGTGTGMMDCPVILQELGRDTWLALTNEHQINKSANKSIRILVTMARSPGSKTNKKIVSFDLSKGGYPDHLEDGYQFQSKNLSLKILGNRRESEGLYFVTVEENVSVHQSCTQLKLYEQVSTPEIKVLNKTQEENGTCHLLLACTVKRGDNVSYSWGDEAGTRLPSQANRSHLLHLILSNQHQDSIYNCTASNPVSSRSRTFNLWQQCRPESYSESSLWLPYIAAPLGVIIFVILVSIATVLVKRYWAPSGKPNHCQPPVEEKSLTIYAQVQKSGPLEKELHDALTDQDPCTTIYVAATEPVPESVQEPNPTTVYASVTLPES", "length": 345 }, "evidence": [ { "id": "A0A8V1AF74", "url": "https://omabrowser.org/oma/group/A0A8V1AF74/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "K7GQV7-1", "protein_name": "Signaling lymphocytic activation molecule family member 1", "gene_name": "SLAMF1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MHKLDSRGSTCLTWSSLCCGVCEQLPAPHQAALPPSPHWLMDPKRRLFSLNVLLLLSLAFELSCTTGEGSMNCPKVLGRLGSSVLLPLTSEGIRKSMNKSIHILVSMAESPVHNIKKKIVSLDLPEGSSPRYLEDGYAFHLENMSLSILESKKEDEGWYFLSLEENVSVQQFCLQLKIYEQVSRPEIKVLNSTQENGNCSLMLACMVEKGDHVTYSWSQEGGVILPSPANCSHLLYLTLGPQHADNVYICTANNPISNRSQTFIPWSRCSPSSSESRQWGLYVGLLLGGIIGVIMILQVVILLLRRRGKANNYQRAMEAKSLTIYAQVQKPGSFQKKPDPLPAQDPCTTIYVAATEPIPEPVQESSSITVYASVTLPES", "length": 379 }, "evidence": [ { "id": "A0A8V1AF74", "url": "https://omabrowser.org/oma/group/A0A8V1AF74/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q13291-1", "protein_name": "Signaling lymphocytic activation molecule", "gene_name": "SLAMF1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDPKGLLSLTFVLFLSLAFGASYGTGGRMMNCPKILRQLGSKVLLPLTYERINKSMNKSIHIVVTMAKSLENSVENKIVSLDPSEAGPPRYLGDRYKFYLENLTLGIRESRKEDEGWYLMTLEKNVSVQRFCLQLRLYEQVSTPEIKVLNKTQENGTCTLILGCTVEKGDHVAYSWSEKAGTHPLNPANSSHLLSLTLGPQHADNIYICTVSNPISNNSQTFSPWPGCRTDPSETKPWAVYAGLLGGVIMILIMVVILQLRRRGKTNHYQTTVEKKSLTIYAQVQKPGPLQKKLDSFPAQDPCTTIYVAATEPVPESVQETNSITVYASVTLPES", "length": 335 }, "evidence": [ { "id": "A0A8V1AF74", "url": "https://omabrowser.org/oma/group/A0A8V1AF74/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9QUM4-1", "protein_name": "Signaling lymphocytic activation molecule", "gene_name": "Slamf1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDPKGSLSWRILLFLSLAFELSYGTGGGVMDCPVILQKLGQDTWLPLTNEHQINKSVNKSVRILVTMATSPGSKSNKKIVSFDLSKGSYPDHLEDGYHFQSKNLSLKILGNRRESEGWYLVSVEENVSVQQFCKQLKLYEQVSPPEIKVLNKTQENENGTCSLLLACTVKKGDHVTYSWSDEAGTHLLSRANRSHLLHITLSNQHQDSIYNCTASNPVSSISRTFNLSSQACKQESSSESSPWMQYTLVPLGVVIIFILVFTAIIMMKRQGKSNHCQPPVEEKSLTIYAQVQKSGPQEKKLHDALTDQDPCTTIYVAATEPAPESVQEPNPTTVYASVTLPES", "length": 343 }, "evidence": [ { "id": "A0A8V1AF74", "url": "https://omabrowser.org/oma/group/A0A8V1AF74/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AF74", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF74" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "immune response", "id": "GO:0006955", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006955", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AF74", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF74" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 143, "end_pos": 145, "annotation": "n_glycosylation_sequon" }, { "start_pos": 151, "end_pos": 153, "annotation": "n_glycosylation_sequon" }, { "start_pos": 159, "end_pos": 161, "annotation": "n_glycosylation_sequon" }, { "start_pos": 178, "end_pos": 180, "annotation": "n_glycosylation_sequon" }, { "start_pos": 45, "end_pos": 47, "annotation": "n_glycosylation_sequon" }, { "start_pos": 75, "end_pos": 77, "annotation": "n_glycosylation_sequon" }, { "start_pos": 90, "end_pos": 92, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AF74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF74" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 132, "end_pos": 215, "start_aa": "Pro", "end_aa": "Cys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 143, "end_pos": 145 }, { "start_pos": 151, "end_pos": 153 }, { "start_pos": 159, "end_pos": 161 }, { "start_pos": 178, "end_pos": 180 }, { "start_pos": 45, "end_pos": 47 }, { "start_pos": 75, "end_pos": 77 }, { "start_pos": 90, "end_pos": 92 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AFS4-1", "uniprot_ac": "A0A8V1AFS4", "uniprot_id": "A0A8V1AFS4_CHICK", "mass": { "chemical_mass": 71774.0, "monoisotopic_mass": 71774.0 }, "refseq": { "ac": "XP_004945993", "name": "serine/threonine kinase-like domain-containing protein STKLD1 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004945993" }, "gene_names": [ { "name": "STKLD1", "type": "recommended", "evidence": [ { "id": "A0A8V1AFS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFS4" } ] }, { "name": "STKLD1", "type": "synonym", "evidence": [ { "id": "XP_004945993", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004945993" } ] } ], "protein_names": [ { "name": "Serine/threonine kinase-like domain-containing protein STKLD1", "type": "recommended", "evidence": [ { "id": "A0A8V1AFS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFS4/entry#names_and_taxonomy" } ] }, { "name": "2.7.11.1", "type": "synonym", "evidence": [ { "id": "A0A8V1AFS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFS4/entry#names_and_taxonomy" } ] }, { "name": "Serine/threonine kinase-like domain-containing protein 1", "type": "synonym", "evidence": [ { "id": "A0A8V1AFS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFS4/entry#names_and_taxonomy" } ] }, { "name": "Sugen kinase 071", "type": "synonym", "evidence": [ { "id": "A0A8V1AFS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFS4/entry#names_and_taxonomy" } ] }, { "name": "serine/threonine kinase-like domain-containing protein STKLD1 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_004945993", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004945993" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052548.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004945993.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004945993", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004945993" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFS4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFS4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "STKLD1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFS4", "locus": { "chromosome": "17", "start_pos": 7508960, "end_pos": 7496146, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028865", "url": "https://www.ensembl.org/id/ENSGALG00010028865" } ] } } ], "crossref": [ { "id": "A0A8V1AFS4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AFS4", "database": "AlphaFoldDB", "categories": [] }, { "id": "417154", "url": "https://www.ncbi.nlm.nih.gov/gene/417154", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AAE2", "url": "https://www.orthodb.org/?gene=A0A8V1AAE2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AFR8", "url": "https://www.orthodb.org/?gene=A0A8V1AFR8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AFS4", "url": "https://www.orthodb.org/?gene=A0A8V1AFS4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AHU7", "url": "https://www.orthodb.org/?gene=A0A8V1AHU7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AK29", "url": "https://www.orthodb.org/?gene=A0A8V1AK29", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ALV2", "url": "https://www.orthodb.org/?gene=A0A8V1ALV2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24363", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24363", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24363:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24363:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00069", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00069", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004945993", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004945993", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "17989", "url": "https://www.rhea-db.org/rhea/17989", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "46608", "url": "https://www.rhea-db.org/rhea/46608", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1AAE2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAE2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AAE2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAE2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFR8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFR8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFR8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFR8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFS4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFS4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFS4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFS4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHU7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHU7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHU7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHU7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AK29", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK29", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AK29-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK29-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALV2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALV2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALV2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALV2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEKYEVLQRLQPGALGTVLVAGLKAERNAKDRFVIKQVECIDEKQANEALKEAMGLLQLHHSSICAYKEMFVTWDNEISSLYLCLVMQHSGQVDLSSLIKTKRQKPEKIADVVLLKFLGQMVDALFYIHKQNIFHRNLKPSNILVTGETSFKLCDFGTETLMTDEWKWKIRVEENCKCWMAPEAFSFSFSDKSDIWSLGCILLDMMTCFVLNAEEITLLLQDIRRDTSHLDRVLSLMEIGENSSLPLFPVLSMMLQIQPSMRTTAKDLIDVPFIGECLIVASSSVIKQKKSLASCVIDMFLEGGIGSILEFMQAFWDVEEAQAKAMQHLAHFVGDKSALPYLLTFTELIVFALKTHTNCFKLQVDGCSLLLEVLSQALEQDVVMVLDENVINSLLEIVRRHSEDEELLSLICPLLMMISADEVVAENLRKAGLTSDLLSILCNFIHNEQICHTSCAVLWSLAVSENSVDQVMLQSAVPIITAVIQEHLQNGAVLKSACSALWALSLQGFLTENDYEPTTVLLMDALRMNLEKPMLVNNTCLALASLLRLSEIAALRFITDSKGSGINLIKDAYRFYCDDPQVVESICVLINEMVQYDDVMLDMLSQQMEELLSEIKSRFPSSMEIMTLADTALLKLQE", "length": 638, "header": "tr|A0A8V1AFS4-1|A0A8V1AFS4_CHICK Isoform 1 of Serine/threonine kinase-like domain-containing protein STKLD1 OS=Gallus gallus OX=9031 GN=STKLD1 PE=4 SV=1 CANONICAL=A0A8V1AFS4-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AAE2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFS4/entry#A0A8V1AAE2-1", "sequence": { "sequence": "MEKYEVLQRLQPGALGTVLVAGLKAERNAKDRFVIKQVECIDEKQANEALKEAMGLLQLHHSSICAYKEMFVTWDNEVLLKFLGQMVDALFYIHKQNIFHRNLKPSNILVTGETSFKLCDFGTETLMTDEWKWKIRVEENCKCWMAPEAFSFSFSDKSDIWSLGCILLDMMTCFVLNAEEITLLLQDIRRDTSHLDRVLSLMEIGENSSLPLFPVLSMMLQIQPSMRTTAKDLIDVPFIGECLIVASSSVIKQKKSLASCVIDMFLEGGIGSILEFMQAFWDVEEAQAKAMQHLAHFVGDKSALPYLLTFTELIVFALKTHTNCFKLQVDGCSLLLEVLSQALEQDVVMVLDENVINSLLEIVRRHSEDEELLSLICPLLMMISADEVVAENLRKAGLTSDLLSILCNFIHNEQICHTSCAVLWSLAVSENSVDQVMLQSAVPIITAVIQEHLQNGAVLKSACSALWALSLQGFLTENDYEPTTVLLMDALRMNLEKPMLVNNTCLALASLLRLSEIAALRFITDSKGSGINLIKDAYRFYCDDPQVVESICVLINEMVQYDDVMLDMLSQQMEELLSEIKSRFPSSMEIMTLADTALLKLQE", "length": 603, "header": "tr|A0A8V1AAE2-1|A0A8V1AFS4_CHICK Computationally mapped isoform of Serine/threonine kinase-like domain-containing protein STKLD1 OS=Gallus gallus OX=9031 GN=STKLD1 PE=4 SV=1 CANONICAL=A0A8V1AFS4-1" }, "locus": { "chromosome": "17", "start_pos": 7508187, "end_pos": 7497196, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069823.1", "url": "https://www.ensembl.org/id/ENSGALT00010069823.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042949.1", "url": "https://www.ensembl.org/id/ENSGALP00010042949.1" } ] } }, { "isoform_ac": "A0A8V1AFR8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFS4/entry#A0A8V1AFR8-1", "sequence": { "sequence": "MVLLKFLGQMVDALFYIHKQNIFHRNLKPSNILVTGETSFKLCDFGTETLMTDEWKWKIRVEENCKCWMAPEAFSFSFSDKSDIWSLGCILLDMMTCFVLNAEEITLLLQDIRRDTSHLDRVLSLMEIGENSSLPLFPVLSMMLQIQPSMRTTAKDLIDVPFIGECLIVASSSVIKQKKSLASCVIDMFLEGGIGSILEFMQAFWDVEEAQAKAMQHLAHFVGDKSALPYLLTFTELIVFALKTHTNCFKLQVDGCSLLLEVLSQALEQDVVMVLDENVINSLLEIVRRHSEDEELLSLICPLLMMISADEVVAENLRKAGLTSDLLSILCNFIHNEQICHTSCAVLWSLAVSENSVDQVMLQSAVPIITAVIQEHLQNGAVLKSACSALWALSLQGFLTENDYEPTTVLLMDALRMNLEKPMLVNNTCLALASLLRLSEIAALRFITDSKGSGINLIKDAYRFYCDDPQVVESICVLINEMVQYDDVMLDMLSQQMEELLSEIKSRFPSSMEIMTLADTALLKLQE", "length": 527, "header": "tr|A0A8V1AFR8-1|A0A8V1AFR8_CHICK Computationally mapped isoform of Serine/threonine kinase-like domain-containing protein STKLD1 OS=Gallus gallus OX=9031 GN=STKLD1 PE=4 SV=1 CANONICAL=A0A8V1AFS4-1" }, "locus": { "chromosome": "17", "start_pos": 7508187, "end_pos": 7499404, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069820.1", "url": "https://www.ensembl.org/id/ENSGALT00010069820.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042946.1", "url": "https://www.ensembl.org/id/ENSGALP00010042946.1" } ] } }, { "isoform_ac": "A0A8V1AFS4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFS4/entry#A0A8V1AFS4-1", "sequence": { "sequence": "MEKYEVLQRLQPGALGTVLVAGLKAERNAKDRFVIKQVECIDEKQANEALKEAMGLLQLHHSSICAYKEMFVTWDNEISSLYLCLVMQHSGQVDLSSLIKTKRQKPEKIADVVLLKFLGQMVDALFYIHKQNIFHRNLKPSNILVTGETSFKLCDFGTETLMTDEWKWKIRVEENCKCWMAPEAFSFSFSDKSDIWSLGCILLDMMTCFVLNAEEITLLLQDIRRDTSHLDRVLSLMEIGENSSLPLFPVLSMMLQIQPSMRTTAKDLIDVPFIGECLIVASSSVIKQKKSLASCVIDMFLEGGIGSILEFMQAFWDVEEAQAKAMQHLAHFVGDKSALPYLLTFTELIVFALKTHTNCFKLQVDGCSLLLEVLSQALEQDVVMVLDENVINSLLEIVRRHSEDEELLSLICPLLMMISADEVVAENLRKAGLTSDLLSILCNFIHNEQICHTSCAVLWSLAVSENSVDQVMLQSAVPIITAVIQEHLQNGAVLKSACSALWALSLQGFLTENDYEPTTVLLMDALRMNLEKPMLVNNTCLALASLLRLSEIAALRFITDSKGSGINLIKDAYRFYCDDPQVVESICVLINEMVQYDDVMLDMLSQQMEELLSEIKSRFPSSMEIMTLADTALLKLQE", "length": 638, "header": "tr|A0A8V1AFS4-1|A0A8V1AFS4_CHICK Isoform 1 of Serine/threonine kinase-like domain-containing protein STKLD1 OS=Gallus gallus OX=9031 GN=STKLD1 PE=4 SV=1 CANONICAL=A0A8V1AFS4-1" }, "locus": { "chromosome": "17", "start_pos": 7508187, "end_pos": 7497196, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069825.1", "url": "https://www.ensembl.org/id/ENSGALT00010069825.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042951.1", "url": "https://www.ensembl.org/id/ENSGALP00010042951.1" } ] } }, { "isoform_ac": "A0A8V1AHU7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFS4/entry#A0A8V1AHU7-1", "sequence": { "sequence": "MEKYEVECIDEKQANEALKEAMGLLQLHHSSICAYKEMFVTWDNEVLLKFLGQMVDALFYIHKQNIFHRNLKPSNILVTGETSFKLCDFGTETLMTDEWKWKIRVEENCKCWMAPEAFSFSFSDKSDIWSLGCILLDMMTCFVLNAEEITLLLQDIRRDTSHLDRVLSLMEIGENSSLPLFPVLSMMLQIQPSMRTTAKDLIDVPFIGECLIVASSSVIKQKKSLASCVIDMFLEGGIGSILEFMQAFWDVEEAQAKAMQHLAHFVGDKSALPYLLTFTELIVFALKTHTNCFKLQVDGCSLLLEVLSQALEQDVVMVLDENVINSLLEIVRRHSEDEELLSLICPLLMMISADEVVAENLRKAGLTSDLLSILCNFIHNEQICHTSCAVLWSLAVSENSVDQVMLQSAVPIITAVIQEHLQNGAVLKSACSALWALSLQGFLTENDYEPTTVLLMDALRMNLEKPMLVNNTCLALASLLRLSEIAALRFITDSKGSGINLIKDAYRFYCDDPQVVESICVLINEMVQYDDVMLDMLSQQMEELLSEIKSRFPSSMEIMTLADTALLKLQE", "length": 571, "header": "tr|A0A8V1AHU7-1|A0A8V1AFS4_CHICK Computationally mapped isoform of Serine/threonine kinase-like domain-containing protein STKLD1 OS=Gallus gallus OX=9031 GN=STKLD1 PE=4 SV=1 CANONICAL=A0A8V1AFS4-1" }, "locus": { "chromosome": "17", "start_pos": 7508187, "end_pos": 7497196, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069822.1", "url": "https://www.ensembl.org/id/ENSGALT00010069822.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042948.1", "url": "https://www.ensembl.org/id/ENSGALP00010042948.1" } ] } }, { "isoform_ac": "A0A8V1AK29-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFS4/entry#A0A8V1AK29-1", "sequence": { "sequence": "MGLLQLHHSSICAYKEMFVTWDNEISSLYLCLVMQHSGQVDLSSLIKTKRQKPEKIADVVLLKFLGQMVDALFYIHKQNIFHRNLKPSNILVTGETSFKLCDFGTETLMTDEWKWKIRVEENCKCWMAPEAFSFSFSDKSDIWSLGCILLDMMTCFVLNAEEITLLLQDIRRDTSHLDRVLSLMEIGENSSLPLFPVLSMMLQIQPSMRTTAKDLIDVPFIGECLIVASSSVIKQKKSLASCVIDMFLEGGIGSILEFMQAFWDVEEAQAKAMQHLAHFVGDKSALPYLLTFTELIVFALKTHTNCFKLQVDGCSLLLEVLSQEVVAENLRKAGLTSDLLSILCNFIHNEQICHTSCAVLWSLAVSENSVDQVMLQSAVPIITAVIQEHLQNGAVLKSACSALWALSLQGFLTENDYEPTTVLLMDALRMNLEKPMLVNNTCLALASLLRLSEIAALRFITDSKGSGINLIKDAYRFYCDDPQVVESICVLINEMVQYDDVMLDMLSQQMEELLSEIKSRFPSSMEIMTLADTALLKLQE", "length": 540, "header": "tr|A0A8V1AK29-1|A0A8V1AFS4_CHICK Computationally mapped isoform of Serine/threonine kinase-like domain-containing protein STKLD1 OS=Gallus gallus OX=9031 GN=STKLD1 PE=4 SV=1 CANONICAL=A0A8V1AFS4-1" }, "locus": { "chromosome": "17", "start_pos": 7508187, "end_pos": 7498226, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069826.1", "url": "https://www.ensembl.org/id/ENSGALT00010069826.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042952.1", "url": "https://www.ensembl.org/id/ENSGALP00010042952.1" } ] } }, { "isoform_ac": "A0A8V1ALV2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFS4/entry#A0A8V1ALV2-1", "sequence": { "sequence": "MEKYEVLQRLQPGALGTVLVAGLKAERNAKDRFVIKQVECIDEKQANEALKEAMGLLQLHHSSICAYKEMFVTWDNEISSLYLCLVMQHSGQVDLSSLIKTKRQKPEKIADVVLLKFLGQMVDALFYIHKQNIFHRNLKPSNILVTGETSFKLCDFGTETLMTDEWKWKIRVEENCKCWMAPEAFSFSFSDKSDIWSLGCILLDMMTCFVLNAEEITLLLQDIRRDTSHLDRVLSLMEIGENSSLPLFPVLSMMLQIQPSMRTTAKDLIDVPFIGECLIVASSSVIKQKKSLASCVIDMFLEGGIGSILEFMQAFWDVEEAQAKAMQHLAHFVGDKSALEQDVVMVLDENVINSLLEIVRRHSEDEELLSLICPLLMMISADEVVAENLRKAGLTSDLLSILCNFIHNEQICHTSCAVLWSLAVSENSVDQVMLQSAVPIITAVIQEHLQNGAVLKSACSALWALSLQGVFSQGFLTENDYEPTTVLLMDALRMNLEKPMLVNNTCLALASLLRLSEIAALRFITDSKGSGINLIKDAYRFYCDDPQVVESICVLINEMVQYDDVMLDMLSQQMEELLSEIKSRFPSSMEIMTLADTALLKLQE", "length": 604, "header": "tr|A0A8V1ALV2-1|A0A8V1AFS4_CHICK Computationally mapped isoform of Serine/threonine kinase-like domain-containing protein STKLD1 OS=Gallus gallus OX=9031 GN=STKLD1 PE=4 SV=1 CANONICAL=A0A8V1AFS4-1" }, "locus": { "chromosome": "17", "start_pos": 7508187, "end_pos": 7497196, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069824.1", "url": "https://www.ensembl.org/id/ENSGALT00010069824.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042950.1", "url": "https://www.ensembl.org/id/ENSGALP00010042950.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFS4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFS4" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFS4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFS4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 242, "end_pos": 244, "annotation": "n_glycosylation_sequon" }, { "start_pos": 537, "end_pos": 539, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "17989", "name": "", "equation": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q6U1I9-1", "A0A8V0XNJ2-1", "A0A8V0ZUL0-1", "A0A8V0ZT63-1", "A0A8V1ACW2-1", "A0A8V0Z1X0-1", "A0A8V0YHN2-1", "A0A8V0YMN5-1", "A0A8V0Z807-1", "A0A8V0Z930-1", "A0A8V0YFR6-1", "A0A1D5P0M9-1", "A0A8V0ZBN6-1", "A0A3Q2U9U9-1", "A0A8V0YXZ5-1", "A0A8V0ZSP4-1", "A0A8V0ZXQ9-1", "A0A8V0ZZV3-1", "A0A8V1ADF0-1", "A0A8V0ZFT3-1", "A0A8V0ZA45-1", "A0A8V0ZB33-1", "A0A8V0ZD70-1", "A0A8V0Z8T4-1", "R4GIN8-1", "A0A8V0ZK64-1", "A0A8V0ZC16-1", "A0A8V0ZWW1-1", "E1BY69-1", "A0A8V0ZDW9-1", "A0A8V0ZKA2-1", "A0A3Q3B2F1-1", "F1P356-1", "A0A8V1AHA8-1", "Q8QFP8-1", "F1P011-1", "A0A8V0YKK3-1", "A0A1D5NWT4-1", "A0A1D5PMQ7-1", "E1BWA3-1", "F1NVF2-1", "A0A1D5PXN4-1", "A0A3Q2TY19-1", "A0A3Q2U592-1", "A0A8V0XCV5-1", "A0A1D5P8A9-1", "A0A1D5PMG2-1", "A0A8V0X1Q7-1", "A0A8V0Y935-1", "A0A8V0YM96-1", "A0A8V0YF83-1", "A0A8V0YJP9-1", "A0A8V1AKW4-1", "A0A8V0ZSB4-1", "F1NBT0-1", "P18652-1", "P21868-1", "P21869-1", "P53666-1", "P79996-1", "Q5F3W3-1", "Q5ZJS0-1", "Q5ZKN1-1", "Q5ZLL1-1", "A0A8V0XCS0-1", "A0A8V0XNK8-1", "A0A8V0XLV6-1", "A0A8V0XDR5-1", "E1BYH2-1", "E1BQN6-1", "A0A8V0XU71-1", "Q5ZJH6-1", "A0A8V0Y3D1-1", "A0A8V0Y7C3-1", "A0A8V0YCY4-1", "A0A8V0YIV6-1", "A0A8V0YK18-1", "A0A8V0YM22-1", "A0A8V0YTN5-1", "A0A8V0YTP2-1", "Q5F3L1-1", "A0A8V0Y3L2-1", "A0A8V0YCY8-1", "A0A8V0Y9Q1-1", "A0A8V0ZD48-1", "A0A8V0ZD60-1", "A0A8V0ZBZ2-1", "A0A8V0Z9J0-1", "A0A8V1ABF3-1", "Q8AYC9-1", "A0A8V0Z927-1", "A0A8V1A2T9-1", "Q5ZKI0-1", "Q7T0B1-1", "P10741-1", "A0A8V0YFH4-1", "E1C848-1", "A0A8V0X8M1-1", "E1BW33-1", "A0A8V0Z283-1", "A0A8V0Z157-1", "A0A3Q2U4X3-1", "A0A8V0XW11-1", "E1BUG0-1", "A0A8V1ABP4-1", "A0A8V1AJA4-1", "A0A8V1AEH4-1", "F1NJH1-1", "A0A8V1AMK5-1", "A0A3Q2TRY2-1", "A0A8V0X3D6-1", "A0A1D5PD64-1", "A0A8V0XQ97-1", "R4GJB8-1", "A0A8V0X5Z8-1", "A0A8V0XG21-1", "A0A8V0XB58-1", "A0A8V0XMX8-1", "A0A8V0XQS0-1", "A0A8V0XW29-1", "A0A8V0Y074-1", "A0A8V0XXB8-1", "A0A8V0XQ14-1", "A0A8V0XMT1-1", "A0A8V0Y457-1", "A0A8V0Y823-1", "A0A8V0Y4L8-1", "A0A8V0XND6-1", "A0A8V0YZ74-1", "A0A8V0YTI1-1", "A0A8V0YLV1-1", "A0A8V0Z2E3-1", "A0A8V0YCV9-1", "A0A8V0YSH3-1", "A0A8V0YYX2-1", "A0A8V0YZY4-1", "Q5ZIU3-1", "A0A8V0YZK0-1", "A0A8V0ZKM9-1", "A0A8V0ZWC7-1", "A0A8V1A1Y7-1", "A0A8V1A069-1", "A0A8V0ZI32-1", "A0A8V0ZH91-1", "E1BQV7-1", "A0A8V0ZRX1-1", "A0A8V0ZUU9-1", "A0A8V1A0Y8-1", "A0A8V1A7E9-1", "A0A8V1A7E0-1", "A0A8V1A3T8-1", "A0A8V1A9S5-1", "A0A8V1A7M0-1", "A0A8V1A675-1", "A0A8V1A1P3-1", "A0A8V1ADT4-1", "E1BWT0-1", "A0A8V1ACF6-1", "A0A8V1ADN9-1", "A0A8V1AM12-1", "A0A8V1A4Q4-1", "Q90891-1", "A0A1D5P517-1", "F1NB57-1", "F1NUX4-1", "A0A8V0ZZE4-1", "P05625-1", "P13863-1", "P67962-1", "Q04982-2", "Q0GGW5-1", "Q6XUX0-1", "Q8QGX4-1", "Q9I9E0-1", "Q9IA88-1", "Q5ZJK4-1", "A0A1D5PTJ8-1", "E1C2I2-1", "F1NCX7-1", "F1NKW3-1", "A0A8V1A0W4-1", "A0A8V1A4J8-1", "A0A8V1ACK0-1", "F1NCY7-1", "A0A8V0X6T4-1", "A0A8V0ZFM2-1", "A0A8V0XUM6-1", "A0A8V0XEA3-1", "A0A8V1AIY7-1", "A0A8V0YHH2-1", "A0A3Q2UI52-1", "A0A8V0ZZK5-1", "A0A8V0ZPX2-1", "A0A8V1ACB5-1", "A0A8V0YDH4-1", "A0A8V1AFS4-1", "A0A8V1AH12-1", "A0A8V0YRC9-1", "A0A8V0ZQT5-1", "A0A8V0ZFP1-1", "E1C764-1", "A0A1D5PUY5-1", "F1P4G3-1", "A0A8V0ZMK1-1", "A0A8V0Y2I5-1", "A0A8V0ZLU3-1", "A0A8V0ZNP7-1", "A0A8V0Z2Z3-1", "A0A8V0YNI5-1", "Q90771-1", "A0A8V0X4P0-1", "A0A8V0X7R2-1", "A0A3Q3A664-1", "A0A8V0YGW2-1", "E1C581-1", "A0A8V1AC40-1", "A0A3Q2TUS7-1", "A0A1D5PA08-1", "A0A8V0XFW1-1", "A0A8V0XAH9-1", "A0A8V1A4A1-1", "A0A8V0ZD40-1", "A0A8V0Z6T1-1", "A0A8V1A4V7-1", "E1C093-1", "A0A8V0YZF2-1", "E1BX69-1", "A0A8V0XI18-1", "A0A8V0Y955-1", "A0A1D5PB73-1", "A0A1D5PV76-1", "A0A1D5PX90-1", "A0A1L1RWI9-1", "A0A3Q2TV19-1", "A0A3Q2UF44-1", "A0A8V0X4Q3-1", "A0A8V0Z124-1", "A0A8V0Z6K4-1", "A0A8V1AE45-1", "A0A8V0YZV9-1", "A0A8V0YYZ3-1", "A0A8V0ZUC6-1", "A0A8V0ZUU8-1", "A0A8V1AG70-1", "F1NA68-1", "F1NLR7-1", "A0A8V0Y6K1-1", "A0A8V0XS42-1", "A0A8V0YRN4-1", "A0A8V0YFP8-1", "A0A8V1A7P9-1", "A0A1D5PRN8-1", "A0A3Q3AAD7-1", "A0A3Q2TWZ8-1", "A0A8V0XBZ0-1", "A0A8V0XFX2-1", "A0A8V0YFL1-1", "A0A8V0YTL9-1", "A0A8V0YMB3-1", "A0A8V0X2Y2-1", "A0A8V0XCY6-1", "A0A3Q2UI62-1", "A0A8V0Y241-1", "A0A8V0Z8G2-1", "A0A8V1ABR8-1", "A0A8V1AP60-1", "A0A8V0YZM1-1", "A0A8V0ZB38-1", "A0A8V0Z466-1", "A0A8V0ZA06-1", "A0A8V1AMQ2-1", "A0A8V0ZGY3-1", "A0A8V0ZQJ2-1", "A0A8V0ZYU6-1", "A0A8V1A513-1", "A0A8V0XE48-1", "A0A8V0XQQ4-1", "A0A8V0XKG0-1" ], "evidence": [ { "id": "17989", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/17989" } ] }, { "id": "46608", "name": "", "equation": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A1D5PUY5-1", "Q6U1I9-1", "A0A8V0XNJ2-1", "A0A8V0ZUL0-1", "A0A8V0ZT63-1", "A0A8V1ACW2-1", "A0A8V0Z1X0-1", "A0A8V0YHN2-1", "A0A8V0YMN5-1", "A0A8V0Z807-1", "A0A8V0Z930-1", "A0A8V0YFR6-1", "A0A1D5P0M9-1", "A0A8V0ZBN6-1", "A0A3Q2U9U9-1", "A0A8V0YRC9-1", "A0A8V0YXZ5-1", "A0A8V0ZSP4-1", "A0A8V0ZXQ9-1", "A0A8V0ZZV3-1", "A0A8V1ADF0-1", "A0A8V0ZFT3-1", "A0A8V0ZA45-1", "A0A8V0ZB33-1", "A0A8V0ZD70-1", "A0A8V0Z8T4-1", "R4GIN8-1", "A0A8V0ZK64-1", "A0A8V0ZC16-1", "A0A8V0ZWW1-1", "E1BY69-1", "A0A8V0ZDW9-1", "A0A8V0ZKA2-1", "A0A3Q3B2F1-1", "F1P356-1", "A0A8V1AHA8-1", "Q8QFP8-1", "F1P011-1", "A0A8V0YKK3-1", "A0A1D5NWT4-1", "A0A1D5PMQ7-1", "E1BWA3-1", "F1NVF2-1", "A0A1D5PXN4-1", "A0A3Q2TY19-1", "A0A3Q2U592-1", "A0A8V0XCV5-1", "A0A1D5P8A9-1", "A0A1D5PMG2-1", "A0A8V0X1Q7-1", "A0A8V0Y935-1", "A0A8V0YM96-1", "A0A8V0YF83-1", "A0A8V0YJP9-1", "A0A8V1AKW4-1", "A0A1D5P517-1", "A0A8V0ZSB4-1", "F1NBT0-1", "P18652-1", "P21868-1", "P21869-1", "P53666-1", "P79996-1", "Q5F3W3-1", "Q5ZJS0-1", "Q5ZKN1-1", "Q5ZLL1-1", "A0A8V0XCS0-1", "A0A8V0XNK8-1", "A0A8V0XLV6-1", "A0A8V0XDR5-1", "E1BYH2-1", "F1NB57-1", "E1BQN6-1", "A0A8V0XU71-1", "Q5ZJH6-1", "A0A8V0Y3D1-1", "A0A8V0Y7C3-1", "A0A8V0YCY4-1", "A0A8V0YIV6-1", "A0A8V0YK18-1", "A0A8V0YM22-1", "A0A8V0YTN5-1", "A0A8V0YTP2-1", "Q5F3L1-1", "A0A8V0XU96-1", "E1C6T4-1", "A0A8V0Y3L2-1", "A0A8V0YCY8-1", "A0A8V0Y9Q1-1", "A0A8V0ZD48-1", "A0A8V0ZD60-1", "A0A8V0ZBZ2-1", "A0A8V0Z9J0-1", "A0A8V1ABF3-1", "Q8AYC9-1", "A0A8V0Z927-1", "A0A8V1A2T9-1", "Q5ZKI0-1", "Q7T0B1-1", "P10741-1", "A0A8V1AMK5-1", "P67962-1", "A0A8V0YFH4-1", "E1C848-1", "A0A8V0X8M1-1", "E1BW33-1", "A0A8V0Z283-1", "A0A8V0Z157-1", "A0A3Q2U4X3-1", "A0A8V0XW11-1", "E1BUG0-1", "A0A8V1ABP4-1", "A0A8V1AJA4-1", "A0A8V1AEH4-1", "F1NJH1-1", "A0A3Q2TRY2-1", "A0A8V0X3D6-1", "A0A1D5PD64-1", "A0A8V0XQ97-1", "R4GJB8-1", "A0A8V0X5Z8-1", "A0A8V0XG21-1", "A0A8V0XB58-1", "A0A8V0XMX8-1", "A0A8V0XQS0-1", "A0A8V0XW29-1", "A0A8V0Y074-1", "A0A8V0XXB8-1", "A0A8V0XQ14-1", "A0A8V0XI18-1", "A0A8V0XMT1-1", "A0A8V0Y457-1", "A0A8V0Y823-1", "A0A8V0Y4L8-1", "A0A8V0XND6-1", "A0A8V0Y8X9-1", "A0A8V0YZ74-1", "A0A8V0YTI1-1", "A0A8V0YLV1-1", "A0A8V0Z2E3-1", "A0A8V0YCV9-1", "A0A8V0YSH3-1", "A0A8V0YYX2-1", "A0A8V0YZY4-1", "Q5ZIU3-1", "A0A8V0YZK0-1", "A0A8V0ZKM9-1", "A0A8V0ZWC7-1", "A0A8V1A1Y7-1", "A0A8V1A069-1", "A0A8V0ZI32-1", "A0A8V0ZH91-1", "E1BQV7-1", "A0A8V0ZRX1-1", "A0A8V0ZUU9-1", "A0A8V1A0Y8-1", "A0A8V1A7E9-1", "A0A8V1A7E0-1", "A0A8V1A3T8-1", "A0A8V1A9S5-1", "A0A8V1A7M0-1", "A0A8V1A675-1", "A0A8V1A1P3-1", "A0A8V1ADT4-1", "E1BWT0-1", "A0A8V1ACF6-1", "A0A8V1ADN9-1", "A0A8V1AM12-1", "A0A8V1A4Q4-1", "Q90891-1", "F1NUX4-1", "A0A8V0ZZE4-1", "P05625-1", "P13863-1", "Q04982-2", "Q0GGW5-1", "Q6XUX0-1", "Q8QGX4-1", "Q9I9E0-1", "Q9IA88-1", "Q5ZJK4-1", "A0A1D5PTJ8-1", "E1C2I2-1", "F1NCX7-1", "F1NKW3-1", "A0A8V1A0W4-1", "A0A8V1A4J8-1", "A0A8V1ACK0-1", "F1NCY7-1", "A0A8V0X6T4-1", "A0A8V0XUM6-1", "A0A8V0XEA3-1", "A0A8V0YHH2-1", "A0A3Q2UI52-1", "A0A8V0ZZK5-1", "A0A8V0ZPX2-1", "A0A8V1ACB5-1", "A0A8V0YDH4-1", "A0A8V1AFS4-1", "A0A8V1AH12-1", "A0A8V0ZQT5-1", "A0A8V0ZFP1-1", "E1C764-1", "F1P4G3-1", "A0A8V0Y2I5-1", "A0A8V0ZLU3-1", "A0A8V0ZNP7-1", "A0A8V0Z2Z3-1", "A0A8V0YNI5-1", "Q90771-1", "A0A8V0X4P0-1", "A0A8V0X7R2-1", "A0A3Q3A664-1", "A0A8V0YGW2-1", "E1C581-1", "A0A8V1AC40-1", "A0A3Q2TUS7-1", "A0A1D5PA08-1", "A0A8V0XFW1-1", "A0A8V0XAH9-1", "A0A8V0ZFM2-1", "A0A8V1A4A1-1", "A0A8V0ZD40-1", "A0A8V0Z6T1-1", "A0A8V1A4V7-1", "A0A8V0YZF2-1", "E1BX69-1", "A0A8V0Y955-1", "A0A1D5PB73-1", "A0A1D5PV76-1", "A0A1D5PX90-1", "A0A1L1RWI9-1", "A0A3Q2TV19-1", "A0A3Q2UF44-1", "A0A8V0X4Q3-1", "A0A8V0Z124-1", "A0A8V0Z6K4-1", "A0A8V1AIY7-1", "A0A8V1AE45-1", "A0A8V0YZV9-1", "A0A8V0YYZ3-1", "A0A8V0ZUC6-1", "A0A8V0ZUU8-1", "A0A8V1AG70-1", "F1NA68-1", "F1NLR7-1", "A0A8V0Y6K1-1", "A0A8V0XS42-1", "A0A8V0YRN4-1", "A0A8V0YFP8-1", "A0A8V1A7P9-1", "A0A1D5PRN8-1", "A0A3Q3AAD7-1", "A0A3Q2TWZ8-1", "A0A8V0XBZ0-1", "A0A8V0XFX2-1", "A0A8V0YFL1-1", "A0A8V0YTL9-1", "A0A8V0YMB3-1", "A0A8V0X2Y2-1", "A0A8V0XCY6-1", "A0A3Q2UI62-1", "A0A8V0Y241-1", "A0A8V0Z8G2-1", "A0A8V1ABR8-1", "A0A8V1AP60-1", "A0A8V0YZM1-1", "A0A8V0ZB38-1", "A0A8V0Z466-1", "A0A8V0ZA06-1", "A0A8V1AMQ2-1", "A0A8V0ZGY3-1", "A0A8V0ZQJ2-1", "A0A8V0ZYU6-1", "A0A8V1A513-1", "A0A8V0XE48-1", "A0A8V0XKG0-1" ], "evidence": [ { "id": "46608", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/46608" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5NWT4", "gene_name": "RPS6KA3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5NWT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NWT4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5NWT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NWT4" } ] } ] }, { "uniprot_ac": "A0A1D5P0M9", "gene_name": "MAP3K13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5P0M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P0M9" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A1D5P0M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P0M9" } ] } ] }, { "uniprot_ac": "A0A1D5P517", "gene_name": "PLK3", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5P517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P517" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A1D5P517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P517" } ] } ] }, { "uniprot_ac": "A0A1D5P8A9", "gene_name": "SNRK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5P8A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P8A9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5P8A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P8A9" } ] } ] }, { "uniprot_ac": "A0A1D5PA08", "gene_name": "STK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PA08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PA08" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5PA08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PA08" } ] } ] }, { "uniprot_ac": "A0A1D5PB73", "gene_name": "CASK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PB73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PB73" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5PB73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PB73" } ] } ] }, { "uniprot_ac": "A0A1D5PD64", "gene_name": "MAP2K3", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PD64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PD64" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A1D5PD64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PD64" } ] } ] }, { "uniprot_ac": "A0A1D5PMG2", "gene_name": "DCLK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PMG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMG2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5PMG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMG2" } ] } ] }, { "uniprot_ac": "A0A1D5PMQ7", "gene_name": "STK40", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PMQ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMQ7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5PMQ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMQ7" } ] } ] }, { "uniprot_ac": "A0A1D5PRN8", "gene_name": "DAPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PRN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRN8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5PRN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRN8" } ] } ] }, { "uniprot_ac": "A0A1D5PTJ8", "gene_name": "MAP3K5", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PTJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PTJ8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A1D5PTJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PTJ8" } ] } ] }, { "uniprot_ac": "A0A1D5PUY5", "gene_name": "PRKCB", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PUY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUY5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A1D5PUY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUY5" } ] } ] }, { "uniprot_ac": "A0A1D5PV76", "gene_name": "STK17A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PV76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PV76" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5PV76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PV76" } ] } ] }, { "uniprot_ac": "A0A1D5PX90", "gene_name": "KSR2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PX90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PX90" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5PX90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PX90" } ] } ] }, { "uniprot_ac": "A0A1D5PXN4", "gene_name": "PRKCD", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PXN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PXN4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A1D5PXN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PXN4" } ] } ] }, { "uniprot_ac": "A0A1L1RWI9", "gene_name": "CAMK4", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1L1RWI9", "database": "UniProtKB", "url": 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= O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q3AAD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3AAD7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q3AAD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3AAD7" } ] } ] }, { "uniprot_ac": "A0A3Q3B2F1", "gene_name": "PKN3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q3B2F1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3B2F1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A3Q3B2F1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3B2F1" } ] } ] }, { "uniprot_ac": "A0A8V0X1Q7", "gene_name": "MELK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X1Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X1Q7" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X1Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X1Q7" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0X1Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X1Q7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0X1Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X1Q7" } ] } ] }, { "uniprot_ac": "A0A8V0X2Y2", "gene_name": "MAPK12", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X2Y2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X2Y2" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0X2Y2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X2Y2" } ] } ] }, { "uniprot_ac": "A0A8V0X3D6", "gene_name": "LOC100858386", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X3D6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X3D6" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0X3D6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X3D6" } ] } ] }, { "uniprot_ac": "A0A8V0X4P0", "gene_name": "CDKL5", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X4P0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X4P0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0X4P0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X4P0" } ] } ] }, { "uniprot_ac": "A0A8V0X4Q3", "gene_name": "ICK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X4Q3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X4Q3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0X4Q3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X4Q3" } ] } ] }, { "uniprot_ac": "A0A8V0X5Z8", "gene_name": "NEK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X5Z8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X5Z8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0X5Z8", "database": "UniProtKB", "url": 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= O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XCS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCS0" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0A8V0XCS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCS0" } ] } ] }, { "uniprot_ac": "A0A8V0XCV5", "gene_name": "MAP3K7", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XCV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCV5" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0XCV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCV5" } ] } ] }, { "uniprot_ac": "A0A8V0XCY6", "gene_name": "TTK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XCY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCY6" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V0XCY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCY6" } ] } ] }, { "uniprot_ac": "A0A8V0XDR5", "gene_name": "IRAK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XDR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XDR5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XDR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XDR5" } ] } ] }, { "uniprot_ac": "A0A8V0XE48", "gene_name": "ROCK2", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XE48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XE48" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "A0A8V0XE48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XE48" } ] } ] }, { "uniprot_ac": "A0A8V0XEA3", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XEA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEA3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XEA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEA3" } ] } ] }, { "uniprot_ac": "A0A8V0XFW1", "gene_name": "SGK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XFW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFW1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XFW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFW1" } ] } ] }, { "uniprot_ac": "A0A8V0XFX2", "gene_name": "NEK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XFX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFX2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XFX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFX2" } ] } ] }, { "uniprot_ac": "A0A8V0XG21", "gene_name": "LOC107050335", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XG21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XG21" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XG21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XG21" } ] } ] }, { "uniprot_ac": "A0A8V0XI18", "gene_name": "ATM", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XI18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XI18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XI18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XI18" } ] } ] }, { "uniprot_ac": "A0A8V0XKG0", "gene_name": "NEK9", "activity": [ { "ec_number": "2.7.11.38", "activity": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XKG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XKG0" } ] }, { "ec_number": "2.7.11.38", "activity": "", "evidence": [ { "id": "A0A8V0XKG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XKG0" } ] } ] }, { "uniprot_ac": "A0A8V0XLV6", "gene_name": "MAPK10", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XLV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLV6" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0XLV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLV6" } ] } ] }, { "uniprot_ac": "A0A8V0XMT1", "gene_name": "MOS", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XMT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMT1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XMT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMT1" } ] } ] }, { "uniprot_ac": "A0A8V0XMX8", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMX8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMX8" } ] } ] }, { "uniprot_ac": "A0A8V0XND6", "gene_name": "RIOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XND6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XND6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XND6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XND6" } ] } ] }, { "uniprot_ac": "A0A8V0XNJ2", "gene_name": "CDK8", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] } ] }, { "uniprot_ac": "A0A8V0XNK8", "gene_name": "PRKCQ", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XNK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNK8" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0XNK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNK8" } ] } ] }, { "uniprot_ac": "A0A8V0XQ14", "gene_name": "PLK4", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQ14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ14" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A8V0XQ14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ14" } ] } ] }, { "uniprot_ac": "A0A8V0XQ97", "gene_name": "CDK14", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQ97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ97" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0XQ97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ97" } ] } ] }, { "uniprot_ac": "A0A8V0XQQ4", "gene_name": "NME7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQQ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQQ4" } ] } ] }, { "uniprot_ac": "A0A8V0XQS0", "gene_name": "STK24", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQS0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XQS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQS0" } ] } ] }, { "uniprot_ac": "A0A8V0XS42", "gene_name": "MAP3K4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XS42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XS42" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0XS42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XS42" } ] } ] }, { "uniprot_ac": "A0A8V0XU71", "gene_name": "MYO3A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XU71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU71" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XU71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU71" } ] } ] }, { "uniprot_ac": "A0A8V0XU96", "gene_name": "PRKD1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XU96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU96" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0XU96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU96" } ] } ] }, { "uniprot_ac": "A0A8V0XUM6", "gene_name": "LATS1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XUM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XUM6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XUM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XUM6" } ] } ] }, { "uniprot_ac": "A0A8V0XW11", "gene_name": "RPS6KA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XW11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW11" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XW11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW11" } ] } ] }, { "uniprot_ac": "A0A8V0XW29", "gene_name": "CDKL2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XW29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW29" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0XW29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW29" } ] } ] }, { "uniprot_ac": "A0A8V0XXB8", "gene_name": "MAPK15", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XXB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXB8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0XXB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXB8" } ] } ] }, { "uniprot_ac": "A0A8V0Y074", "gene_name": "NEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y074", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y074" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y074", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y074" } ] } ] }, { "uniprot_ac": "A0A8V0Y241", "gene_name": "LOC426385", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y241", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y241" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y241", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y241" } ] } ] }, { "uniprot_ac": "A0A8V0Y2I5", "gene_name": "CDK7", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] } ] }, { "uniprot_ac": "A0A8V0Y3D1", "gene_name": "LRRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y3D1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3D1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y3D1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3D1" } ] } ] }, { "uniprot_ac": "A0A8V0Y3L2", "gene_name": "MLK4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y3L2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3L2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0Y3L2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3L2" } ] } ] }, { "uniprot_ac": "A0A8V0Y457", "gene_name": "PRPF4B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y457", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y457" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y457", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y457" } ] } ] }, { "uniprot_ac": "A0A8V0Y4L8", "gene_name": "HUNK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y4L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y4L8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y4L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y4L8" } ] } ] }, { "uniprot_ac": "A0A8V0Y6K1", "gene_name": "MAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6K1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6K1" } ] } ] }, { "uniprot_ac": "A0A8V0Y7C3", "gene_name": "DAPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y7C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7C3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y7C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7C3" } ] } ] }, { "uniprot_ac": "A0A8V0Y823", "gene_name": "SRPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y823", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y823" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y823", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y823" } ] } ] }, { "uniprot_ac": "A0A8V0Y8X9", "gene_name": "PRKACA", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y8X9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8X9" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0A8V0Y8X9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8X9" } ] } ] }, { "uniprot_ac": "A0A8V0Y935", "gene_name": "MAST4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y935", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y935" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y935", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y935" } ] } ] }, { "uniprot_ac": "A0A8V0Y955", "gene_name": "PAK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y955", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y955" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y955", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y955" } ] } ] }, { "uniprot_ac": "A0A8V0Y9Q1", "gene_name": "LOC107055388", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y9Q1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9Q1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y9Q1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9Q1" } ] } ] }, { "uniprot_ac": "A0A8V0YCV9", "gene_name": "SIK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YCV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YCV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCV9" } ] } ] }, { "uniprot_ac": "A0A8V0YCY4", "gene_name": "AURKB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YCY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YCY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY4" } ] } ] }, { "uniprot_ac": "A0A8V0YCY8", "gene_name": "RIOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YCY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YCY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY8" } ] } ] }, { "uniprot_ac": "A0A8V0YDH4", "gene_name": "ALPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YDH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDH4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YDH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDH4" } ] } ] }, { "uniprot_ac": "A0A8V0YF83", "gene_name": "WNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YF83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF83" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YF83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF83" } ] } ] }, { "uniprot_ac": "A0A8V0YFH4", "gene_name": "NRK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFH4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YFH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFH4" } ] } ] }, { "uniprot_ac": "A0A8V0YFL1", "gene_name": "CDK19", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0YFL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL1" } ] } ] }, { "uniprot_ac": "A0A8V0YFP8", "gene_name": "RIPK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFP8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YFP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFP8" } ] } ] }, { "uniprot_ac": "A0A8V0YFR6", "gene_name": "TNIK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFR6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YFR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFR6" } ] } ] }, { "uniprot_ac": "A0A8V0YGW2", "gene_name": "STK32B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YGW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGW2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YGW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGW2" } ] } ] }, { "uniprot_ac": "A0A8V0YHH2", "gene_name": "STK38L", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YHH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHH2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YHH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHH2" } ] } ] }, { "uniprot_ac": "A0A8V0YHN2", "gene_name": "RPS6KA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YHN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YHN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN2" } ] } ] }, { "uniprot_ac": "A0A8V0YIV6", "gene_name": "DYRK1A", "activity": [ { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] } ] }, { "uniprot_ac": "A0A8V0YJP9", "gene_name": "RIOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YJP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YJP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP9" } ] } ] }, { "uniprot_ac": "A0A8V0YK18", "gene_name": "CDC42BPB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YK18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YK18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK18" } ] } ] }, { "uniprot_ac": "A0A8V0YKK3", "gene_name": "MAP4K4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKK3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKK3" } ] } ] }, { "uniprot_ac": "A0A8V0YLV1", "gene_name": "MARK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + 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} ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YMN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN5" } ] } ] }, { "uniprot_ac": "A0A8V0YNI5", "gene_name": "NIM1K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YNI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNI5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YNI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNI5" } ] } ] }, { "uniprot_ac": "A0A8V0YRC9", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] }, { "ec_number": "2.7.11.1", "activity": 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"ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTL9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTL9" } ] } ] }, { "uniprot_ac": "A0A8V0YTN5", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTN5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTN5" } ] } ] }, { "uniprot_ac": "A0A8V0YTP2", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTP2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTP2" } ] } ] }, { "uniprot_ac": "A0A8V0YXZ5", "gene_name": "CDC42BPA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YXZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXZ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YXZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXZ5" } ] } ] }, { "uniprot_ac": "A0A8V0YYX2", "gene_name": "PAK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YYX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYX2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YYX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYX2" } ] } ] }, { "uniprot_ac": "A0A8V0YYZ3", "gene_name": "SPEG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YYZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYZ3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YYZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYZ3" } ] } ] }, { "uniprot_ac": "A0A8V0YZ74", "gene_name": "MAP2K5", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZ74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZ74" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V0YZ74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZ74" } ] } ] }, { "uniprot_ac": "A0A8V0YZF2", "gene_name": "PAK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZF2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YZF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZF2" } ] } ] }, { "uniprot_ac": "A0A8V0YZK0", "gene_name": "MAP3K6", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZK0" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0YZK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZK0" } ] } ] }, { "uniprot_ac": "A0A8V0YZM1", "gene_name": "MOK", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] }, { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": 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"id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] } ] }, { "uniprot_ac": "A0A8V0Z2E3", "gene_name": "PDIK1L", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z2E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2E3" } ] }, { "ec_number": 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"database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z466" } ] } ] }, { "uniprot_ac": "A0A8V0Z6K4", "gene_name": "PIK3R4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z6K4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6K4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z6K4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6K4" } ] } ] }, { "uniprot_ac": "A0A8V0Z6T1", "gene_name": "ERN2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z6T1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6T1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z6T1", "database": "UniProtKB", "url": 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{ "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z930", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z930" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V0Z930", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z930" } ] } ] }, { "uniprot_ac": "A0A8V0Z9J0", "gene_name": "CIT", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z9J0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9J0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z9J0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9J0" } ] } ] }, { "uniprot_ac": "A0A8V0ZA06", "gene_name": "CDKL1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA06" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0ZA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA06" } ] } ] }, { "uniprot_ac": "A0A8V0ZA45", "gene_name": "MAP4K5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZA45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA45" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZA45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA45" } ] } ] }, { "uniprot_ac": "A0A8V0ZB33", "gene_name": "CAMK2G", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZB33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB33" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V0ZB33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB33" } ] } ] }, { "uniprot_ac": "A0A8V0ZB38", "gene_name": "CIITA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZB38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB38" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZB38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB38" } ] } ] }, { "uniprot_ac": "A0A8V0ZBN6", "gene_name": "MAP2K1", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZBN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBN6" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V0ZBN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBN6" } ] } ] }, { "uniprot_ac": "A0A8V0ZBZ2", "gene_name": "MAP3K9", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZBZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBZ2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0ZBZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBZ2" } ] } ] }, { "uniprot_ac": "A0A8V0ZC16", "gene_name": "KALRN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZC16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC16" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZC16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC16" } ] } ] }, { "uniprot_ac": "A0A8V0ZD40", "gene_name": "CDC2L1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] } ] }, { "uniprot_ac": "A0A8V0ZD48", "gene_name": "PRKCE", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD48" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0ZD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD48" } ] } ] }, { "uniprot_ac": "A0A8V0ZD60", "gene_name": "STK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZD60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD60" } ] } ] }, { "uniprot_ac": "A0A8V0ZD70", "gene_name": "DCLK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD70" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZD70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD70" } ] } ] }, { "uniprot_ac": "A0A8V0ZDW9", "gene_name": "NEK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZDW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDW9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZDW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDW9" } ] } ] }, { "uniprot_ac": "A0A8V0ZFM2", "gene_name": "LMTK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZFM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFM2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZFM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFM2" } ] } ] }, { "uniprot_ac": "A0A8V0ZFP1", "gene_name": "TTBK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZFP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFP1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZFP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFP1" } ] } ] }, { "uniprot_ac": "A0A8V0ZFT3", "gene_name": "LRRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZFT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFT3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZFT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFT3" } ] } ] }, { "uniprot_ac": "A0A8V0ZGY3", "gene_name": "HIPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZGY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGY3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZGY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGY3" } ] } ] }, { "uniprot_ac": "A0A8V0ZH91", "gene_name": "WNK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": 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"ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZKM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKM9" } ] } ] }, { "uniprot_ac": "A0A8V0ZLU3", "gene_name": "TLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZLU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLU3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZLU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLU3" } ] } ] }, { "uniprot_ac": "A0A8V0ZMK1", "gene_name": "PIKFYVE", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] }, { "ec_number": "2.7.1.150", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] }, { "ec_number": "2.7.1.150", "activity": "", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] } ] }, { "uniprot_ac": "A0A8V0ZNP7", "gene_name": "SGK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZNP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNP7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZNP7", "database": 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O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] } ] }, { "uniprot_ac": "A0A8V0ZT63", "gene_name": "STK25", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZT63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT63" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZT63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT63" } ] } ] }, { "uniprot_ac": "A0A8V0ZUC6", 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"activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU8" } ] } ] }, { "uniprot_ac": "A0A8V0ZUU9", "gene_name": "MKNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU9" } ] } ] }, { "uniprot_ac": "A0A8V0ZWC7", "gene_name": "EIF2AK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZWC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWC7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZWC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWC7" } ] } ] }, { "uniprot_ac": "A0A8V0ZWW1", "gene_name": "MAP3K12", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZWW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWW1" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0ZWW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWW1" } ] } ] }, { "uniprot_ac": "A0A8V0ZXQ9", "gene_name": "PRKG1", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZXQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXQ9" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0A8V0ZXQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXQ9" } ] } ] }, { "uniprot_ac": "A0A8V0ZYU6", "gene_name": "TNNI3K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZYU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYU6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZYU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYU6" } ] } ] }, { "uniprot_ac": "A0A8V0ZZE4", "gene_name": "OBSCN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZZE4", "database": "UniProtKB", "url": 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"ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZZV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZV3" } ] } ] }, { "uniprot_ac": "A0A8V1A069", "gene_name": "TESK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A069", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A069" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1A069", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A069" } ] } ] }, { "uniprot_ac": "A0A8V1A0W4", "gene_name": "ULK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A0W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0W4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": 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"activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4J8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A4J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4J8" } ] } ] }, { "uniprot_ac": "A0A8V1A4Q4", "gene_name": "MAPK3", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Q4" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1A4Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Q4" } ] } ] }, { "uniprot_ac": "A0A8V1A4V7", "gene_name": "HIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": 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H(+).", "evidence": [ { "id": "A0A8V1A675", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A675" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A675", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A675" } ] } ] }, { "uniprot_ac": "A0A8V1A7E0", "gene_name": "DYRK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1A7E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E0" } ] } ] }, { "uniprot_ac": "A0A8V1A7E9", "gene_name": "SIK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E9" } ] } ] }, { "uniprot_ac": "A0A8V1A7M0", "gene_name": "STK39", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M0" } ] } ] }, { "uniprot_ac": "A0A8V1A7P9", "gene_name": "DCAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] } ] }, { "uniprot_ac": "A0A8V1A9S5", "gene_name": "NUAK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A9S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9S5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A9S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9S5" } ] } ] }, { "uniprot_ac": "A0A8V1ABF3", "gene_name": "PRKAA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] } ] }, { "uniprot_ac": "A0A8V1ABP4", "gene_name": "DSTYK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP4" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1ABP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP4" } ] } ] }, { "uniprot_ac": "A0A8V1ABR8", "gene_name": "CAMK4L", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR8" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1ABR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR8" } ] } ] }, { "uniprot_ac": "A0A8V1AC40", "gene_name": "CDK18", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AC40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC40" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V1AC40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC40" } ] } ] }, { "uniprot_ac": "A0A8V1ACB5", "gene_name": "MAPK13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACB5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1ACB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACB5" } ] } ] }, { "uniprot_ac": "A0A8V1ACF6", "gene_name": "PIM1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF6" } ] } ] }, { "uniprot_ac": "A0A8V1ACK0", "gene_name": "MAPKAPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK0" } ] } ] }, { "uniprot_ac": "A0A8V1ACW2", "gene_name": "WNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACW2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACW2" } ] } ] }, { "uniprot_ac": "A0A8V1ADF0", "gene_name": "MAP2K2", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF0" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V1ADF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF0" } ] } ] }, { "uniprot_ac": "A0A8V1ADN9", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADN9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1ADN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADN9" } ] } ] }, { "uniprot_ac": "A0A8V1ADT4", "gene_name": "MKNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADT4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ADT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADT4" } ] } ] }, { "uniprot_ac": "A0A8V1AE45", "gene_name": "ERN1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AE45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE45" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AE45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE45" } ] } ] }, { "uniprot_ac": "A0A8V1AEH4", "gene_name": "STK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEH4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEH4" } ] } ] }, { "uniprot_ac": "A0A8V1AFS4", "gene_name": "STKLD1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AFS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFS4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AFS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFS4" } ] } ] }, { "uniprot_ac": "A0A8V1AG70", "gene_name": "LOC100857512", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AG70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG70" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AG70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG70" } ] } ] }, { "uniprot_ac": "A0A8V1AH12", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AH12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH12" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AH12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH12" } ] } ] }, { "uniprot_ac": "A0A8V1AHA8", "gene_name": "NEK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AHA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHA8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AHA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHA8" } ] } ] }, { "uniprot_ac": "A0A8V1AIY7", "gene_name": "AATK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AIY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AIY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIY7" } ] } ] }, { "uniprot_ac": "A0A8V1AJA4", "gene_name": "RPS6KB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AJA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJA4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AJA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJA4" } ] } ] }, { "uniprot_ac": "A0A8V1AKW4", "gene_name": "MAP2K4", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AKW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKW4" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V1AKW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKW4" } ] } ] }, { "uniprot_ac": "A0A8V1AM12", "gene_name": "GSG2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AM12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM12" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AM12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM12" } ] } ] }, { "uniprot_ac": "A0A8V1AMK5", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AMK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V1AMK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK5" } ] } ] }, { "uniprot_ac": "A0A8V1AMQ2", "gene_name": "CAMKK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AMQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ2" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1AMQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ2" } ] } ] }, { "uniprot_ac": "A0A8V1AP60", "gene_name": "KSR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AP60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AP60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP60" } ] } ] }, { "uniprot_ac": "E1BQN6", "gene_name": "PRKCZ", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQN6" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1BQN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQN6" } ] } ] }, { "uniprot_ac": "E1BQV7", "gene_name": "SLK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQV7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BQV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQV7" } ] } ] }, { "uniprot_ac": "E1BUG0", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] } ] }, { "uniprot_ac": "E1BW33", "gene_name": "SMG1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BW33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BW33" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BW33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BW33" } ] } ] }, { "uniprot_ac": "E1BWA3", "gene_name": "PRKCI", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BWA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWA3" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1BWA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWA3" } ] } ] }, { "uniprot_ac": "E1BWT0", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BWT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWT0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BWT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWT0" } ] } ] }, { "uniprot_ac": "E1BX69", "gene_name": "EIF2AK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BX69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BX69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BX69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BX69" } ] } ] }, { "uniprot_ac": "E1BY69", "gene_name": "PIM3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BY69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BY69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY69" } ] } ] }, { "uniprot_ac": "E1BYH2", "gene_name": "TAOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BYH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYH2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BYH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYH2" } ] } ] }, { "uniprot_ac": "E1C093", "gene_name": "PIK3CG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] } ] }, { "uniprot_ac": "E1C2I2", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C2I2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2I2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C2I2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2I2" } ] } ] }, { "uniprot_ac": "E1C581", "gene_name": "TBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C581", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C581" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C581", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C581" } ] } ] }, { "uniprot_ac": "E1C6T4", "gene_name": "PRKD3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C6T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C6T4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1C6T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C6T4" } ] } ] }, { "uniprot_ac": "E1C764", "gene_name": "BMP2K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C764", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C764" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C764", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C764" } ] } ] }, { "uniprot_ac": "E1C848", "gene_name": "MAP3K8", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C848", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C848" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1C848", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C848" } ] } ] }, { "uniprot_ac": "F1NA68", "gene_name": "CDK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NA68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NA68" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1NA68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NA68" } ] } ] }, { "uniprot_ac": "F1NB57", "gene_name": "PLK2", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NB57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NB57" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "F1NB57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NB57" } ] } ] }, { "uniprot_ac": "F1NBT0", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NBT0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NBT0" } ] } ] }, { "uniprot_ac": "F1NCX7", "gene_name": "PLK1", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NCX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCX7" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "F1NCX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCX7" } ] } ] }, { "uniprot_ac": "F1NCY7", "gene_name": "MAPKAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NCY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NCY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCY7" } ] } ] }, { "uniprot_ac": "F1NJH1", "gene_name": "PRKCH", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NJH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJH1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1NJH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJH1" } ] } ] }, { "uniprot_ac": "F1NKW3", "gene_name": "MAP3K15", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NKW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NKW3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1NKW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NKW3" } ] } ] }, { "uniprot_ac": "F1NLR7", "gene_name": "CLK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NLR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLR7" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "F1NLR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLR7" } ] } ] }, { "uniprot_ac": "F1NUX4", "gene_name": "MTOR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NUX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NUX4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NUX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NUX4" } ] } ] }, { "uniprot_ac": "F1NVF2", "gene_name": "MAP2K6", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NVF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVF2" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "F1NVF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVF2" } ] } ] }, { "uniprot_ac": "F1P011", "gene_name": "CAMK2A", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1P011", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P011" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F1P011", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P011" } ] } ] }, { "uniprot_ac": "F1P356", "gene_name": "NUAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1P356", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P356" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1P356", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P356" } ] } ] }, { "uniprot_ac": "F1P4G3", "gene_name": "HIPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1P4G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P4G3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1P4G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P4G3" } ] } ] }, { "uniprot_ac": "P05625", "gene_name": "RAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05625", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05625" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P05625", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05625" } ] } ] }, { "uniprot_ac": "P10741", "gene_name": "MOS", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P10741", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P10741" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P10741", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P10741" } ] } ] }, { "uniprot_ac": "P13863", "gene_name": "CDK1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13863" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13863" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13863" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13863" } ] } ] }, { "uniprot_ac": "P18652", "gene_name": "RPS6KA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P18652", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18652" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P18652", "database": 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"gene_name": "LIMK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P53666", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P53666" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P53666", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P53666" } ] } ] }, { "uniprot_ac": "P67962", "gene_name": "CSNK1A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P67962", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67962" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P67962", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67962" } ] } ] }, { "uniprot_ac": "P79996", "gene_name": "MAPK9", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AEW6-1", "uniprot_ac": "A0A8V1AEW6", "uniprot_id": "A0A8V1AEW6_CHICK", "mass": { "chemical_mass": 42613.0, "monoisotopic_mass": 42613.0 }, "refseq": { "ac": "XP_004948731", "name": "PML-RARA-regulated adapter molecule 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004948731" }, "gene_names": [ { "name": "PRAM1", "type": "recommended", "evidence": [ { "id": "A0A8V1AEW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEW6" } ] }, { "name": "PRAM1", "type": "synonym", "evidence": [ { "id": "XP_004948731", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004948731" } ] } ], "protein_names": [ { "name": "PML-RARA regulated adaptor molecule 1", "type": "synonym", "evidence": [ { "id": "A0A8V1AEW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEW6/entry#names_and_taxonomy" } ] }, { "name": "PML-RARA-regulated adapter molecule 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_004948731", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004948731" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052559.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004948731.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004948731", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004948731" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEW6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEW6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PRAM1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEW6", "locus": {} } ], "crossref": [ { "id": "A0A8V1AEW6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AEW6", "database": "AlphaFoldDB", "categories": [] }, { "id": "420067", "url": "https://www.ncbi.nlm.nih.gov/gene/420067", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR029294", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029294", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036028", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036028", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043443", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043443", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "KMKPMTL", "url": "https://omabrowser.org/oma/group/KMKPMTL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AC13", "url": "https://www.orthodb.org/?gene=A0A8V1AC13", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AEW6", "url": "https://www.orthodb.org/?gene=A0A8V1AEW6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AJ56", "url": "https://www.orthodb.org/?gene=A0A8V1AJ56", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AJ61", "url": "https://www.orthodb.org/?gene=A0A8V1AJ61", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16830", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16830", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16830:SF11", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16830:SF11", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14603", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14603", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004948731", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004948731", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AC13", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC13", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AC13-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC13-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AEW6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEW6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AEW6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEW6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJ56", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ56", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJ56-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ56-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJ61", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ61", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJ61-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ61-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MELPEGKEAAGRHLRAKLKDGRKPPAGGGRAWGPPAAFPATEPGRAPTPGSKGEPPPAPPVAGRVGVSGTPPPRSKAQSEGPGSRPMPVPQSPEWMARLKKGIAPSAAAAKPGGRDAADNKGVGATSHPPPRNPPPQKWPLLKDTAAPALPATGAAAAGGIRGSGHPPRRKPLPHAAVLGARPAKPRRPPSVDLQKFHKAAPPGEPGRTAAGPWSAALGYPTPFPPRDALSTAGGEEEIYDDVESVELLRRDRSFPPPPAFRPPAHLHPKGGGGTAGGGAAQTPSTVALLVAAQRGAQSTRKVRPMTLKECKKEEKADREFQKKFKFEGNITILTQMMVDPAATEKRGGGKNLPLRRGEILDVIQFTNKEQILCRNSQRRYGYVPRAAMLHLDTDIYDDVDLYE", "length": 404, "header": "tr|A0A8V1AEW6-1|A0A8V1AEW6_CHICK Isoform 1 of PML-RARA regulated adaptor molecule 1 OS=Gallus gallus OX=9031 GN=PRAM1 PE=4 SV=1 CANONICAL=A0A8V1AEW6-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AC13-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEW6/entry#A0A8V1AC13-1", "sequence": { "sequence": "MELPEGKEAAGRHLRAKLKDGRKPPAGGGRAWGPPAAFPATEPGRAPTPGSKGEPPPAPPVAGRVGVSGTPPPRSKAQSEGPGSRPMPVPQSPEWMARLKKGIAPSAAAAKPGGRDAADNKGVGATSHPPPRNPPPQKWPLLKDTAAPALPATGAAAAGGIRGSGHPPRRKPLPHAAVLGARPAKPRRPPSVDLQKFHKAAPPGEPGRTAAGPWSAALGYPTPFPPRDALSTAGGEEEIYDDVESVELLRRDRSFPPPPAFRPPAHLHPKGGGGAAQTPSTVALLVAAQRGAQSTRKVRPMTLKECKKEEKADREFQKKFKFEGNITILTQMMVDPAATEKRGGGKNLPLRRGEILDVIQFTNKEQILCRNSQRRYGYVPRAAMLHL", "length": 387, "header": "tr|A0A8V1AC13-1|A0A8V1AEW6_CHICK Computationally mapped isoform of PML-RARA regulated adaptor molecule 1 OS=Gallus gallus OX=9031 GN=PRAM1 PE=4 SV=1 CANONICAL=A0A8V1AEW6-1" }, "locus": { "chromosome": "28", "start_pos": 1326765, "end_pos": 1322352, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068025.1", "url": "https://www.ensembl.org/id/ENSGALT00010068025.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041768.1", "url": "https://www.ensembl.org/id/ENSGALP00010041768.1" } ] } }, { "isoform_ac": "A0A8V1AEW6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEW6/entry#A0A8V1AEW6-1", "sequence": { "sequence": "MELPEGKEAAGRHLRAKLKDGRKPPAGGGRAWGPPAAFPATEPGRAPTPGSKGEPPPAPPVAGRVGVSGTPPPRSKAQSEGPGSRPMPVPQSPEWMARLKKGIAPSAAAAKPGGRDAADNKGVGATSHPPPRNPPPQKWPLLKDTAAPALPATGAAAAGGIRGSGHPPRRKPLPHAAVLGARPAKPRRPPSVDLQKFHKAAPPGEPGRTAAGPWSAALGYPTPFPPRDALSTAGGEEEIYDDVESVELLRRDRSFPPPPAFRPPAHLHPKGGGGTAGGGAAQTPSTVALLVAAQRGAQSTRKVRPMTLKECKKEEKADREFQKKFKFEGNITILTQMMVDPAATEKRGGGKNLPLRRGEILDVIQFTNKEQILCRNSQRRYGYVPRAAMLHLDTDIYDDVDLYE", "length": 404, "header": "tr|A0A8V1AEW6-1|A0A8V1AEW6_CHICK Isoform 1 of PML-RARA regulated adaptor molecule 1 OS=Gallus gallus OX=9031 GN=PRAM1 PE=4 SV=1 CANONICAL=A0A8V1AEW6-1" }, "locus": { "chromosome": "28", "start_pos": 1327219, "end_pos": 1322352, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068027.1", "url": "https://www.ensembl.org/id/ENSGALT00010068027.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041770.1", "url": "https://www.ensembl.org/id/ENSGALP00010041770.1" } ] } }, { "isoform_ac": "A0A8V1AJ56-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEW6/entry#A0A8V1AJ56-1", "sequence": { "sequence": "MECCAGGEEEIYDDVESVELLRRDRSFPPPPAFRPPAHLHPKGGGGTAGGGAAQTPSTVALLVAAQRGAQSTRKVRPMTLKECKKEEKADREFQKKFKFEGNITILTQMMVDPAATEKRGGGKNLPLRRGEILDVIQFTNKEQILCRNSQRRYGYVPRAAMLHLDTDIYDDVDLYE", "length": 176, "header": "tr|A0A8V1AJ56-1|A0A8V1AEW6_CHICK Computationally mapped isoform of PML-RARA regulated adaptor molecule 1 OS=Gallus gallus OX=9031 GN=PRAM1 PE=4 SV=1 CANONICAL=A0A8V1AEW6-1" }, "locus": { "chromosome": "28", "start_pos": 1327219, "end_pos": 1324290, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068024.1", "url": "https://www.ensembl.org/id/ENSGALT00010068024.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041767.1", "url": "https://www.ensembl.org/id/ENSGALP00010041767.1" } ] } }, { "isoform_ac": "A0A8V1AJ61-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEW6/entry#A0A8V1AJ61-1", "sequence": { "sequence": "MGDGYPTPFPPRDALSTAGGEEEIYDDVESVELLRRDRSFPPPPAFRPPAHLHPKGGGGTAGGGAAQTPSTVALLVAAQRGAQSTRKVRPMTLKECKKEEKADREFQKKFKFEGNITILTQMMVDPAATEKRGGGKNLPLRRGEILDVIQFTNKEQILCRNSQRRYGYVPRAAMLHLDTDIYDDVDLYE", "length": 189, "header": "tr|A0A8V1AJ61-1|A0A8V1AEW6_CHICK Computationally mapped isoform of PML-RARA regulated adaptor molecule 1 OS=Gallus gallus OX=9031 GN=PRAM1 PE=4 SV=1 CANONICAL=A0A8V1AEW6-1" }, "locus": { "chromosome": "28", "start_pos": 1327219, "end_pos": 1322345, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068029.1", "url": "https://www.ensembl.org/id/ENSGALT00010068029.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041772.1", "url": "https://www.ensembl.org/id/ENSGALP00010041772.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 48, "start_aa": "Thr", "end_pos": 48, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr48", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 70, "start_aa": "Thr", "end_pos": 70, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr70", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEW6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEW6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "integrin-mediated signaling pathway", "id": "GO:0007229", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007229", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEW6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEW6" } ], "pmid": "" }, { "name": "protein localization to plasma membrane", "id": "GO:0072659", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072659", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEW6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEW6" } ], "pmid": "" }, { "name": "T cell receptor signaling pathway", "id": "GO:0050852", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050852", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEW6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEW6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 330, "end_pos": 332, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AEW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEW6" }, { "id": "PF14603", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14603" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Helically-extended SH3", "eco_id": "ECO_0000259", "start_pos": 321, "end_pos": 401, "start_aa": "Phe", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 48, 70 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 330, "end_pos": 332 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": 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"uniprot_ac": "A0A8V1AF93", "uniprot_id": "A0A8V1AF93_CHICK", "mass": { "chemical_mass": 75933.0, "monoisotopic_mass": 75933.0 }, "refseq": {}, "gene_names": [ { "name": "INPP5E", "type": "recommended", "evidence": [ { "id": "A0A8V1AF93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF93" } ] } ], "protein_names": [ { "name": "Inositol polyphosphate-5-phosphatase E", "type": "synonym", "evidence": [ { "id": "A0A8V1AF93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF93/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AF93", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF93" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "INPP5E", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF93", "locus": { "chromosome": "17", "start_pos": 8491012, "end_pos": 8481208, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028134", "url": "https://www.ensembl.org/id/ENSGALG00010028134" } ] } } ], "crossref": [ { "id": "A0A8V1AF93", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AF93", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd09095", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09095", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "417135", "url": "https://www.ncbi.nlm.nih.gov/gene/417135", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000300", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000300", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036691", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036691", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042478", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042478", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:417135", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417135", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HADYKLR", "url": "https://omabrowser.org/oma/group/HADYKLR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ACH5", "url": "https://www.orthodb.org/?gene=A0A8V1ACH5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AF93", "url": "https://www.orthodb.org/?gene=A0A8V1AF93", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AF98", "url": "https://www.orthodb.org/?gene=A0A8V1AF98", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AHM9", "url": "https://www.orthodb.org/?gene=A0A8V1AHM9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46625", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46625", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46625:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46625:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF22669", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22669", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-1660514", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1660514", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5624958", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5624958", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "22764", "url": "https://www.rhea-db.org/rhea/22764", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "25528", "url": "https://www.rhea-db.org/rhea/25528", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "32955", "url": "https://www.rhea-db.org/rhea/32955", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1ACH5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACH5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ACH5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACH5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AF93", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF93", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AF93-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF93-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AF98", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF98", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AF98-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF98-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHM9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHM9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHM9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHM9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSSLNGFSQHSGTCVTQRAEGGAVQDLQAKKAGKAAKKETSGNGVLTFESPPRVDTLLNETLKLLPDELKANVKVKSITPRPPRKPRLERAASLDEKNWKRWRRFRTSQESLTDPNETSSSNGSLQEAALTSPIRGRATPCSQCCEPNSLHSSPDASEESPVGKSKGSTSDLGKRASEISSAFGGLLRGKAFAGSKPRLSQIMPARPLPPMELNVASHTLRTANKIDPDLMDYRHYSQHKFGRVSNSLSDTRLHGNGIVYDNCSTDSMKSTFSLLTPIRSKDVRSRSYLEGSLLASGALLGAEELSRCFPDRNVGIFVATWNMQGQKELPENLDDFLLPTDPDYAQDMYVIGVQEGCPDSCCSLLQKRVGNPPPGDAGPPLRHALLCCARSALHVSLHSKGPDLVLLRCVVQYELENGEVKGLLLPEVEYATVTTRIVSQIKTKGALGICFTFFGTSFLFITSHFTSGDSKVNERKLDYNKTIQALTLPKVVPDTNPYRSSSGDVTTRFDEVFWFGDFNFRLNKDRETVDSILNQNPETGVSKLLAYDQLTSEMGRGSIFKGFQEADIHFRPSYKFDIGKDSYDTTSKQRTPSYTDRVVFRSRYRDDIQAVKYSSCPVIKTSDHRPVFALFRVKVRPGRDNIPLAAGQFDRELYLIGIKRRITRELQNRRQQKDQKSSSICSIS", "length": 684, "header": "tr|A0A8V1AF93-1|A0A8V1AF93_CHICK Isoform 1 of Inositol polyphosphate-5-phosphatase E OS=Gallus gallus OX=9031 GN=INPP5E PE=4 SV=1 CANONICAL=A0A8V1AF93-1" }, "isoforms": [ { "isoform_ac": "A0A8V1ACH5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF93/entry#A0A8V1ACH5-1", "sequence": { "sequence": "MSSLNGFSQHSGTCVTQRAEGGAVQDLQAKKAGKAAKKETSGNGVLTFESPPRVDTLLNETLKLLPDELKANVKVKSITPRPPRKPRLERAASLDEKNWKRWRRFRTSQESLTDPNETSSSNGSLQEAALTSPIRGRATPCSQCCEPNSLHSSPDASEESPVGKSKGSTSDLGKRASEISSAFGGLLRGKAFAGSKPRLSQIMPARPLPPMELNVASHTLRTANKIDPDLMDYRHYSQHKFGRVSNSLSDTRLHGNGIVYDNCSTDSMKSTFSLLTPIRSKDVRSRSYLEGSLLASGALLGAEELSRCFPDRNVGIFVATWNMQGQKKRVGNPPPGDAGPPLRHALLCCARSALHVSLHSKGPDLVLLRCVVQYELENGEVKGLLLPEVEYATVTTRIVSQIKTKGALGICFTFFGTSFLFITSHFTSGDSKVNERKLDYNKTIQALTLPKVVPDTNPYRSSSGDVTTRFDEVFWFGDFNFRLNKDRETVDSILNQNPETGVSKLLAYDQLTSEMGRGSIFKGFQEADIHFRPSYKFDIGKDSYDTTSKQRTPSYTDRVVFRSRYRDDIQAVKYSSCPVIKTSDHRPVFALFRVKVRPGRDNIPLAAGQFDRELYLIGIKRRITRELQNRRQQKDQKSSSICSIS", "length": 645, "header": "tr|A0A8V1ACH5-1|A0A8V1AF93_CHICK Computationally mapped isoform of Inositol polyphosphate-5-phosphatase E OS=Gallus gallus OX=9031 GN=INPP5E PE=4 SV=1 CANONICAL=A0A8V1AF93-1" }, "locus": { "chromosome": "17", "start_pos": 8489165, "end_pos": 8482246, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068178.1", "url": "https://www.ensembl.org/id/ENSGALT00010068178.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041921.1", "url": "https://www.ensembl.org/id/ENSGALP00010041921.1" } ] } }, { "isoform_ac": "A0A8V1AF93-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF93/entry#A0A8V1AF93-1", "sequence": { "sequence": "MSSLNGFSQHSGTCVTQRAEGGAVQDLQAKKAGKAAKKETSGNGVLTFESPPRVDTLLNETLKLLPDELKANVKVKSITPRPPRKPRLERAASLDEKNWKRWRRFRTSQESLTDPNETSSSNGSLQEAALTSPIRGRATPCSQCCEPNSLHSSPDASEESPVGKSKGSTSDLGKRASEISSAFGGLLRGKAFAGSKPRLSQIMPARPLPPMELNVASHTLRTANKIDPDLMDYRHYSQHKFGRVSNSLSDTRLHGNGIVYDNCSTDSMKSTFSLLTPIRSKDVRSRSYLEGSLLASGALLGAEELSRCFPDRNVGIFVATWNMQGQKELPENLDDFLLPTDPDYAQDMYVIGVQEGCPDSCCSLLQKRVGNPPPGDAGPPLRHALLCCARSALHVSLHSKGPDLVLLRCVVQYELENGEVKGLLLPEVEYATVTTRIVSQIKTKGALGICFTFFGTSFLFITSHFTSGDSKVNERKLDYNKTIQALTLPKVVPDTNPYRSSSGDVTTRFDEVFWFGDFNFRLNKDRETVDSILNQNPETGVSKLLAYDQLTSEMGRGSIFKGFQEADIHFRPSYKFDIGKDSYDTTSKQRTPSYTDRVVFRSRYRDDIQAVKYSSCPVIKTSDHRPVFALFRVKVRPGRDNIPLAAGQFDRELYLIGIKRRITRELQNRRQQKDQKSSSICSIS", "length": 684, "header": "tr|A0A8V1AF93-1|A0A8V1AF93_CHICK Isoform 1 of Inositol polyphosphate-5-phosphatase E OS=Gallus gallus OX=9031 GN=INPP5E PE=4 SV=1 CANONICAL=A0A8V1AF93-1" }, "locus": { "chromosome": "17", "start_pos": 8489165, "end_pos": 8482246, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068175.1", "url": "https://www.ensembl.org/id/ENSGALT00010068175.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041918.1", "url": "https://www.ensembl.org/id/ENSGALP00010041918.1" } ] } }, { "isoform_ac": "A0A8V1AF98-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF93/entry#A0A8V1AF98-1", "sequence": { "sequence": "MSSLNGFSQHSGTCVTQRAEGGAVQDLQAKKAGKAAKKETSGNGVLTFESPPRVDTLLNETLKLLPDELKANVKVKSITPRPPRKPRLERAASLDEKNWKRWRRFRTSQESLTDPNETSSSNGSLQEAALTSPIRGRATPCSQCCEPNSLHSSPDASEESPVGKSKGSTSDLGKRASEISSAFGGLLRGKAFAGSKPRLSQIMPARPLPPMELNVASHTLRTANKIDPDLMDYRHYSQHKFGRVSNSLSDTRLHGNGIVYDNCSTDSMKSTFSLLTPIRSKDVRSRSYLEGSLLASGALLGAEELSRCFPDRNVGIFVATWNMQGQKELPENLDDFLLPTDPDYAQDMYVIGVQEGCPDRREWEIRLQETLGPHYVMLYSAAHGVLYMSVFIRRDLIWFCSAGDSKVNERKLDYNKTIQALTLPKVVPDTNPYRSSSGDVTTRFDEVFWFGDFNFRLNKDRETVDSILNQNPETGVSKLLAYDQLTSEMGRGSIFKGFQEADIHFRPSYKFDIGKDSYDTTSKQRTPSYTDRVVFRSRYRDDIQAVKYSSCPVIKTSDHRPVFALFRVKVRPGRDNIPLAAGQFDRELYLIGIKRRITRELQNRRQQKDQKSSSICSIS", "length": 619, "header": "tr|A0A8V1AF98-1|A0A8V1AF98_CHICK Computationally mapped isoform of Inositol polyphosphate-5-phosphatase E OS=Gallus gallus OX=9031 GN=INPP5E PE=4 SV=1 CANONICAL=A0A8V1AF93-1" }, "locus": { "chromosome": "17", "start_pos": 8489165, "end_pos": 8482246, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068180.1", "url": "https://www.ensembl.org/id/ENSGALT00010068180.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041923.1", "url": "https://www.ensembl.org/id/ENSGALP00010041923.1" } ] } }, { "isoform_ac": "A0A8V1AHM9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF93/entry#A0A8V1AHM9-1", "sequence": { "sequence": "MSSLNGFSQHSGTCVTQRAEGGAVQDLQAKKAGKAAKKETSGNGVLTFESPPRVDTLLNETLKLLPDELKANVKVKSITPRPPRKPRLERAASLDEKNWKRWRRFRTSQESLTDPNETSSSNGSLQEAALTSPIRGRATPCSQCCEPNSLHSSPDASEESPVGKSKGSTSDLGKRASEISSAFGGLLRGKAFAGSKPRLSQIMPARPLPPMELNVASHTLRTANKIDPDLMDYRHYSQHKFGRVSNSLSDTRLHGNGIVYDNCSTDSMKSTFSLLTPIRSKDVRSRSYLEGSLLASGALLGAEELSRCFPDRNVGIFVATWNMQGQKELPENLDDFLLPTDPDYAQDMYVIGVQEGCPDRREWEIRLQETLGPHYVMLYSAAHGVLYMSVFIRRDLIWFCSEVEYATVTTRIVSQIKTKGALGICFTFFGTSFLFITSHFTSGDSKVNERKLDYNKTIQALTLPKVVPDTNPYRSSSGDVTTRFDEVFWFGDFNFRLNKDRETVDSILNQNPETGVSKLLAYDQLTSEMGRGSIFKGFQEADIHFRPSYKFDIGKDSYDTTSKQRTPSYTDRVVFRSRYRDDIQAVKYSSCPVIKTSDHRPVFALFRVKVRPGRDNIPLAAGQFDRELYLIGIKRRITRELQNRRQQKDQKSSSICSIS", "length": 659, "header": "tr|A0A8V1AHM9-1|A0A8V1AF93_CHICK Computationally mapped isoform of Inositol polyphosphate-5-phosphatase E OS=Gallus gallus OX=9031 GN=INPP5E PE=4 SV=1 CANONICAL=A0A8V1AF93-1" }, "locus": { "chromosome": "17", "start_pos": 8489165, "end_pos": 8482246, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068179.1", "url": "https://www.ensembl.org/id/ENSGALT00010068179.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041922.1", "url": "https://www.ensembl.org/id/ENSGALP00010041922.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:417135", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417135", "resource": "KEGG Pathway" }, { "id": "R-GGA-1660514", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1660514", "resource": "Reactome", "description": "Synthesis of PIPs at the Golgi membrane" }, { "id": "R-GGA-5624958", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5624958", "resource": "Reactome", "description": "ARL13B-mediated ciliary trafficking of INPP5E" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287AEE9-1", "protein_name": "Phosphatidylinositol polyphosphate 5-phosphatase type IV", "gene_name": "INPP5E", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPSKWASRGHSEVAPQQPITAQEPEGRMLKGQLPNTDEELAPRPGSPAPPTAPRLGPEKSPVLPLDTAAPVSSKEDDPQAKARPFTPKPPTRPRLERALSLDEKSWRKRRFRTSREDLAARNGASPSGGSLPDKAPETPAHGGSPPCLSTSLQEIPTARGALGGGGPSTWGSCLSGMISTSLDLLHRDGAAARSSPRLASVLPARPLPAMDHSVASESLRTAHKVDADHADYKLRLQARLFRAHSSLGPGRPPSPLACDDGSLHSARSTFSLLAPIRAQDVRSRSYLEGSLLASGALMGADELARYFPDRTVALFVATWNMQGQKELPPNLDELLLPAEADYAQDLYVVGVQEGCSDRREWETRLQETLGPHYVMLHSAAHGALYLSVLIRRDLIWFCSEVESATVTTRIVSQIKTKGALGVSFTFFGTSFLFITSHFTSGDGKVGERLTDYSKTIQGLALPRTVPDTSPYRSDAADVTTRFDGVFWFGDFNFRLSGGRAAVEAMLKREAGASVQALLQHDQLAREMSRGSVFKGFQEPDIHFLPSYKFDVGKDSYDTTSKQRVPSYTDRVLYRSRHRDDICPLKYSCCPGIRTSDHRPVYGLFRVKVRPGRDNIPLAAGKFDRELYLLGIKRRISKETQRQQALKSQHASAICTVS", "length": 657 }, "evidence": [ { "id": "A0A8V1AF93", "url": "https://omabrowser.org/oma/group/A0A8V1AF93/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "E1BAU6-1", "protein_name": "Phosphatidylinositol polyphosphate 5-phosphatase type IV", "gene_name": "INPP5E", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPSKLVSLGHSETASQQPTAQGCLCPEGSMLKGLLPNSDEEPVPCLGSPAAGGRQGPERSPELPLDTPEQVSNEDPRAQARPFTPKPPPPRPRLERALSLDEKGWRKRRFRTSREDLTVRNGASPSGGSLQDEVPGTPARSGSPPCLSASLQEIPTARRAPGSGGPSSWGNCLSGMISTSLDLLHREGASAGSTPRLASLLSPRPLPAMARNMASEGLRTANKVDPDHADYKLRLQARLFRAHSSLGPGRPPSPLAYDDCSLHSSRSTFSLLAPIRAKDVRSRSYLEGSLLATGALMGADELARYFPDRSVALFVATWNMQGQKELPPNLDELLLPAEADLAQDLYVVGVQEGCSDRREWEARLQETLGPHYVMLYSAAHGALYMAVLIRRDLIWFCSEVESSTVTTRIVSQIKTKGALGVSFTFFGTSLLFITSHFTSGDGKVGERLVDYSKTVQGLALPKNVPDTSPYRSDAADVTTRFDEVFWFGDFNFRLSGGRAAVEAILKQDLSSSVQALLQHDQLTREMQRGSIFKGFQEPDIHFLPSYKFDVGKDSYDTTSKQRTPSYTDRILYRSRHQGDICPVKYSSCPGVRTSDHRPVYGLFRVKVRPGRDNIPLAAGKFDRDLYLLGIKRRISREIQRQQALKSQHASAICTVS", "length": 656 }, "evidence": [ { "id": "A0A8V1AF93", "url": "https://omabrowser.org/oma/group/A0A8V1AF93/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q9JII1-1", "protein_name": "Phosphatidylinositol polyphosphate 5-phosphatase type IV", "gene_name": "Inpp5e", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPSKSACLRHTEAPGQLEGRMLQGQPPNTEKKLIPTPGFLPASDSQGSETNPMPPFSIPAKTSNQNPQTKANLITPQPPIRPKLERTLSLDDKGWRRRRFRGSQEDLTVQNGASPCRGSLQDSVAQSPAYSRPLPCLSTSLQEIPKSRRATGSEGGSPSLWSDCLSGMISTSLDLLHRDAASGGPPSRLASLHASHTPPAMDLSIASSSLRTANKVDPEHTDYKLRMQTRLVRAHSNLGPSRPRSPLAGDDHSIHSARSFSLLAPIRTKDIRSRSYLEGSLLASGALLGAEELARYFPDRNMALFVATWNMQGQKELPASLDEFLLPTEADYTQDLYVIGIQEGCSDRREWETRLQETLGPQYVLLSSAAHGVLYMSLFIRRDLIWFCSEVEYSTVTTRIVSQIKTKGALGVSFTFFGTSFLFITSHFTSGDGKVAERLLDYSRTIQALALPRNVPDTNPYRSSAGDVTTRFDEVFWFGDFNFRLSGGRVAVEAFLKQKPEVDVLALLQHDQLTREMKKGSIFRGFEEAEIHFLPSYKFDIGKDTYDSTSKQRTPSYTDRVLYKSRHKGDICPMKYSSCPGIKTSDHRPVYGLFQVKVRPGRDNIPLAAGKFDRELYLIGIKRRISKEIQRQEALKSQSSSAVCTVS", "length": 647 }, "evidence": [ { "id": "A0A8V1AF93", "url": "https://omabrowser.org/oma/group/A0A8V1AF93/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NRR6-1", "protein_name": "Phosphatidylinositol polyphosphate 5-phosphatase type IV", "gene_name": "INPP5E", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPSKAENLRPSEPAPQPPEGRTLQGQLPGAPPAQRAGSPPDAPGSESPALACSTPATPSGEDPPARAAPIAPRPPARPRLERALSLDDKGWRRRRFRGSQEDLEARNGTSPSRGSVQSEGPGAPAHSCSPPCLSTSLQEIPKSRGVLSSERGSPSSGGNPLSGVASSSPNLPHRDAAVAGSSPRLPSLLPPRPPPALSLDIASDSLRTANKVDSDLADYKLRAQPLLVRAHSSLGPGRPRSPLACDDCSLRSAKSSFSLLAPIRSKDVRSRSYLEGSLLASGALLGADELARYFPDRNVALFVATWNMQGQKELPPSLDEFLLPAEADYAQDLYVIGVQEGCSDRREWETRLQETLGPHYVLLSSAAHGVLYMSLFIRRDLIWFCSEVECSTVTTRIVSQIKTKGALGISFTFFGTSFLFITSHFTSGDGKVAERLLDYTRTVQALVLPRNVPDTNPYRSSAADVTTRFDEVFWFGDFNFRLSGGRTVVDALLCQGLVVDVPALLQHDQLIREMRKGSIFKGFQEPDIHFLPSYKFDIGKDTYDSTSKQRTPSYTDRVLYRSRHKGDICPVSYSSCPGIKTSDHRPVYGLFRVKVRPGRDNIPLAAGKFDRELYLLGIKRRISKEIQRQQALQSQNSSTICSVS", "length": 644 }, "evidence": [ { "id": "A0A8V1AF93", "url": "https://omabrowser.org/oma/group/A0A8V1AF93/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9WVR1-1", "protein_name": "Phosphatidylinositol polyphosphate 5-phosphatase type IV", "gene_name": "Inpp5e", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPSKSACLRHTEAPGQLEGRMLQGQLSNPEKKLIPTSASLPAADSQSSQTNSMPPLSMPAKPSNQNLQAKANLITPQPPIRPKLERTLSLDDKGWRRRRFRGSQEDLTVQNGASPCRGSLQDSVAQSPAYSRPLPCLSTSLQEIPKPRRATGSEGGSPSLWSDCLSGMISTSLDLLHREAASGGPHSRLASLRATHTPPAMDLNIASSSLRTANKVDPEHTDYKLRMQNRLVRAHSNLGPSRPRSPLAGDDHSIHSARSSFSLLAPIRTKDIRSRSYLEGSLLASGALLGADELARYFPDRNMALFVATWNMQGQKELPASLDEFLLPTEADYTQDLYVIGVQEGCSDRREWETRLQETLGPQYVLLSSAAHGVLYMSLFIRRDLIWFCSEVEYSTVTTRIVSQIKTKGALGVSFTFFGTSFLFITSHFTSGDGKVAERLLDYNRTIQALALPRNVPDTNPYRSSAGDVTTRFDEVFWFGDFNFRLSGGRVAVEAFLKQDPEVDVLALLQHDQLTREMKKGSIFKGFEEAEIHFLPSYKFDIGKDTYDSTSKQRTPSYTDRVLYKSRHKGDICPMKYSSCPGIKTSDHRPVYGLFRVKVRPGRDNIPLAAGKFDRELYLIGIKRRISKEIQRQEALKSQSSSAVCTVS", "length": 648 }, "evidence": [ { "id": "A0A8V1AF93", "url": "https://omabrowser.org/oma/group/A0A8V1AF93/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "phosphatidylinositol dephosphorylation", "id": "GO:0046856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046856", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AF93", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF93" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "inositol-polyphosphate 5-phosphatase activity", "id": "GO:0004445", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004445", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AF93", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF93" } ], "pmid": "" }, { "name": "phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity", "id": "GO:0004439", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004439", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AF93", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF93" } ], "pmid": "" }, { "name": "phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity", "id": "GO:0034485", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034485", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AF93", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF93" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AF93", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF93" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AF93", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF93" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", 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"https://www.ensembl.org/id/ENSGALG00010027650" } ] } } ], "crossref": [ { "id": "A0A8V1AF79", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AF79", "database": "AlphaFoldDB", "categories": [] }, { "id": "427087", "url": "https://www.ncbi.nlm.nih.gov/gene/427087", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR010422", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010422", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR054414", "url": "https://www.ebi.ac.uk/interpro/entry/IPR054414", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:427087", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427087", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FEERMMP", "url": "https://omabrowser.org/oma/group/FEERMMP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ACL6", "url": "https://www.orthodb.org/?gene=A0A8V1ACL6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AF79", "url": "https://www.orthodb.org/?gene=A0A8V1AF79", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AH75", "url": "https://www.orthodb.org/?gene=A0A8V1AH75", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21680", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21680", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21680:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21680:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06244", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06244", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1ACL6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACL6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ACL6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACL6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AF79", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF79", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AF79-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF79-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AH75", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH75", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AH75-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH75-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPKKFQGENTKSAAARARKAEAKAAADAKRQQELEDAYWKDDDKHVMRKEQRKEEREKRRLEQLERKKELQRLLEEEDSKLKGKSPKQATPGKVTRAQIEETIRKDQQQKENADTAEKEKTHLEVPLEENINRRVLEEGTVEARTIEDAIAVLRYVANDVDRHPERRMKAAFTAFEEVNLPRLKQENPNMRLSQLKQLLKKEWMKSPENPMNQRHKAYNSQK", "length": 222, "header": "tr|A0A8V1AF79-1|A0A8V1AF79_CHICK Isoform 1 of Coiled-coil domain containing 124 OS=Gallus gallus OX=9031 GN=CCDC124 PE=1 SV=1 CANONICAL=A0A8V1AF79-1" }, "isoforms": [ { "isoform_ac": "A0A8V1ACL6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF79/entry#A0A8V1ACL6-1", "sequence": { "sequence": "MPKKFQGENTKSAAARARKAEAKAAADAKRQQELEDAYWKDDDKHVMRKEQRKEEREKRRLEQLERKKELQRLLEEEDSKLKGKSPKQATPGKVTRAQIEETIRKDQQQKENADTAEKEKTHLEVPLEENINRRVLEEGTVEARTIEDAIAVLSVANDVDRHPERRMKAAFTAFEEVNLPRLKQENPNMRLSQLKQLLKKEWMKSPENPMNQRHKAYNSQK", "length": 221, "header": "tr|A0A8V1ACL6-1|A0A8V1AF79_CHICK Computationally mapped isoform of Coiled-coil domain containing 124 OS=Gallus gallus OX=9031 GN=CCDC124 PE=1 SV=1 CANONICAL=A0A8V1AF79-1" }, "locus": { "chromosome": "28", "start_pos": 3790922, "end_pos": 3784156, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067015.1", "url": "https://www.ensembl.org/id/ENSGALT00010067015.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040978.1", "url": "https://www.ensembl.org/id/ENSGALP00010040978.1" } ] } }, { "isoform_ac": "A0A8V1AF79-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF79/entry#A0A8V1AF79-1", "sequence": { "sequence": "MPKKFQGENTKSAAARARKAEAKAAADAKRQQELEDAYWKDDDKHVMRKEQRKEEREKRRLEQLERKKELQRLLEEEDSKLKGKSPKQATPGKVTRAQIEETIRKDQQQKENADTAEKEKTHLEVPLEENINRRVLEEGTVEARTIEDAIAVLRYVANDVDRHPERRMKAAFTAFEEVNLPRLKQENPNMRLSQLKQLLKKEWMKSPENPMNQRHKAYNSQK", "length": 222, "header": "tr|A0A8V1AF79-1|A0A8V1AF79_CHICK Isoform 1 of Coiled-coil domain containing 124 OS=Gallus gallus OX=9031 GN=CCDC124 PE=1 SV=1 CANONICAL=A0A8V1AF79-1" }, "locus": { "chromosome": "28", "start_pos": 3790922, "end_pos": 3784156, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067013.1", "url": "https://www.ensembl.org/id/ENSGALT00010067013.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040977.1", "url": "https://www.ensembl.org/id/ENSGALP00010040977.1" } ] } }, { "isoform_ac": "A0A8V1AH75-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF79/entry#A0A8V1AH75-1", "sequence": { "sequence": "QPWRLPLCSSWADCSLLQVLLGAVGSSPCLLQGESSALLAEEREKRRLEQLERKKELQRLLEEEDSKLKGKSPKQATPGKVTRAQIEETIRKDQQQKENADTAEKEKTHLEVPLEENINRRVLEEGTVEARTIEDAIAVLSVANDVDRHPERRMKAAFTAFEEVNLPRLKQENPNMRLSQLKQLLKKEWMKSPENPMNQRHKAYNSQK", "length": 208, "header": "tr|A0A8V1AH75-1|A0A8V1AF79_CHICK Computationally mapped isoform of Coiled-coil domain containing 124 OS=Gallus gallus OX=9031 GN=CCDC124 PE=1 SV=1 CANONICAL=A0A8V1AF79-1" }, "locus": { "chromosome": "28", "start_pos": 3790922, "end_pos": 3789540, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067009.1", "url": "https://www.ensembl.org/id/ENSGALT00010067009.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040975.1", "url": "https://www.ensembl.org/id/ENSGALP00010040975.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 90, "start_aa": "Thr", "end_pos": 90, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr90", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:427087", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427087", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZUL1-1", "protein_name": "Coiled-coil domain containing 124", "gene_name": "Ccdc124", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPKKFQGENSKSAAARARRAEAKAAADAKKQKELEDAYWKDEDKHVMRKEQRKEEKEKRRLEQLERKKETQRLLEEEDSRLKGGKAPRVAPAKVTRAQIEDSLRKEQRAEPVEKAKSHLELPLEENLNRRLQEEGSVEARTVEDAIAVLSVAEEADRHPERRMRAAFTAFEEVQLPRLKQENPNMRLSQLKQLLKKEWLRSPDNPMNQRALPFNAPK", "length": 217 }, "evidence": [ { "id": "A0A8V1AF79", "url": "https://omabrowser.org/oma/group/A0A8V1AF79/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1S924-1", "protein_name": "Coiled-coil domain containing 124", "gene_name": "CCDC124", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPKKFQGENTKSAAARARRAEAKAAADAKKQKELEDAYWKDEDKHVMRKEQRKEEKEKRRLEQLERKKETQRLLEEEDSKLKGGKAPRVAAPSKVTRAQIEETLRRDHQHKEASDAAEKAKSHLEVPLEENVNRRVLEEGSVEARTIEDAIAVLSLAEEAADRHPERRMRAAFTAFEEAQLPRLKQENPNMRLSQLKQLLKKEWLRSPDNPMNQRVMPFNAPK", "length": 223 }, "evidence": [ { "id": "A0A8V1AF79", "url": "https://omabrowser.org/oma/group/A0A8V1AF79/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3H4B6-1", "protein_name": "Coiled-coil domain-containing protein 124", "gene_name": "Ccdc124", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MPKKFQGENSKSAAARARRAEAKAAADAKKQKELEDAYWKDEDKHVMRKEQRKEEKEKRRLEQLERKKETQRLLEEEDSRLKGGKAPRVAPAKVTRAQIEDSLRREQRVESVEKAKSHLELPLEENLNRRLQEEGSLEARTVEDAIAVLSVAEDADRHPERRMRAAFTAFEEVQLPRLKQENPNMRLSQLKQLLKKEWLRSPDNPMNQRVLPFNTPK", "length": 217 }, "evidence": [ { "id": "A0A8V1AF79", "url": "https://omabrowser.org/oma/group/A0A8V1AF79/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q2TBV6-1", "protein_name": "Coiled-coil domain-containing protein 124", "gene_name": "CCDC124", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPKKFQGENTKSAAARARRAEAKAAADAKKQKELEDAYWRDEDKHVMRKEQRKEEKEKRRLEQLERKKETQRLLEEEDSKLKGGKAPRVAASSKVTRAQIEETLRRDHQHKESPDPAEKAKSHLEVPLEENVNRRVLEEGSVEARTIEDAIAVLSVTEEAVDRHPERRMRAAYTAFEEAQLPRLKQENPNMRLSQLKQMLKKEWLRSPDNPMNQRAVPFNTPK", "length": 223 }, "evidence": [ { "id": "A0A8V1AF79", "url": "https://omabrowser.org/oma/group/A0A8V1AF79/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q54GW3-1", "protein_name": "Coiled-coil domain-containing protein 124 homolog", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGGKKFGTNSKAEEARSKKAEVKKNENEKKQRDKEDKMWEETDTKILDKQKKQKEKEEKAREDAKKKQEAKELLQQEDKEIKERYGKPSDTKVTRFEIQQKRDKEQKQREKELASRPSDPRVVVVPTTTTTTTTTTTTTTGSDDHEEEDFNLEENMNHILREQRLKDGKDVIDARDINEAIGALSGNDGKEQHPERRMKAAFNAYEEENLPVLRKENPSLRLTQVKQLLWKNWLKAPENPFNQVGSQ", "length": 247 }, "evidence": [ { "id": "A0A8V1AF79", "url": "https://omabrowser.org/oma/group/A0A8V1AF79/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q6PHE8-1", "protein_name": "Coiled-coil domain-containing protein 124", "gene_name": "ccdc124", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MPKKFQGENSKSATARARKAEAKAVADARKQKELEDALWEDNDKRVVKKEQRKDDKERKRLEALERKRENQRLLEEEDSKIKGKQTKEGPSKVTRAQIEETLQSKQNVKEIKEKEKSHLDVPLEENVNRIVPEEGTVEARTIEDAIAVLSTKEDLDRHPERRMKAAYTAFEEANMPRVKMENPNMRLSQLKQQLKKEWTKSPENPLNQRAASYNTK", "length": 216 }, "evidence": [ { "id": "A0A8V1AF79", "url": "https://omabrowser.org/oma/group/A0A8V1AF79/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q96CT7-1", "protein_name": "Coiled-coil domain-containing protein 124", "gene_name": "CCDC124", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPKKFQGENTKSAAARARRAEAKAAADAKKQKELEDAYWKDDDKHVMRKEQRKEEKEKRRLDQLERKKETQRLLEEEDSKLKGGKAPRVATSSKVTRAQIEDTLRRDHQLREAPDTAEKAKSHLEVPLEENVNRRVLEEGSVEARTIEDAIAVLSVAEEAADRHPERRMRAAFTAFEEAQLPRLKQENPNMRLSQLKQLLKKEWLRSPDNPMNQRAVPFNAPK", "length": 223 }, "evidence": [ { "id": "A0A8V1AF79", "url": "https://omabrowser.org/oma/group/A0A8V1AF79/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9D8X2-1", "protein_name": "Coiled-coil domain-containing protein 124", "gene_name": "Ccdc124", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKKFQGENSKSAAARARRAEAKAAADAKKQKELEDAYWKDEDKHVMRKEQRKEEKEKRRLEQLERKKETQRLLEEEDSRLKGGKAPRVAPAKVTRAQIEDSLRREQRAEPVEKAKSHLELPLEENLNRRLQEEGSVEARTVEDAIAVLSVAEEADRHPERRMRAAFTAFEEVQLPRLKQENPNMRLSQLKQLLKKEWLRSPDNPMNQRALPFNAPK", "length": 217 }, "evidence": [ { "id": "A0A8V1AF79", "url": "https://omabrowser.org/oma/group/A0A8V1AF79/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VE08-1", "protein_name": "Coiled-coil domain-containing protein", "gene_name": "Dmel\\CG6013", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MPKKMGINSKAVEARERKEATKKATQEKKSKEAEDRLWRDDDKNLAKKQQRKDEEERKRAEAAKRKAEAKALLDQEMSSINTQRKQPLAKINRQMILEEMEKKQRVIEAINEANKPMAARVVVQNHIEENLNRSMADTDVASNIDEAIVVLSVNDSEEDKHPEKRMRAAYKTFEANNLPRIKAENPSLRMSQWKQLLMKEWNKSPDNPFNQAR", "length": 213 }, "evidence": [ { "id": "A0A8V1AF79", "url": "https://omabrowser.org/oma/group/A0A8V1AF79/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "midbody", "id": "GO:0030496", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030496", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AF79", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF79" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AF79", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF79" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AF79", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF79" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AF79", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF79" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AF79", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF79" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "transcription by RNA polymerase II", "id": "GO:0006366", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006366", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AF79", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF79" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AF79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF79" }, { "id": "PF06244", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06244" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Coiled-coil", "eco_id": "ECO_0000259", "start_pos": 130, "end_pos": 213, "start_aa": "Asn", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": 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"A0A8V1ACP9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACP9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFF7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFF7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFF7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFF7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJM3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJM3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJM3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJM3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSGPNGDPHVALGPAGRDGGDEDGDGFGEEAINSMLDQISSCLDHLEEKNDHLHACLKELLESNRQTRLEFQQQSEQHSMGADMQGPQPPV", "length": 91, "header": "tr|A0A8V1AFF7-1|A0A8V1AFF7_CHICK Isoform 1 of Bublin coiled coil protein OS=Gallus gallus OX=9031 GN=BBLN PE=4 SV=1 CANONICAL=A0A8V1AFF7-1" }, "isoforms": [ { "isoform_ac": "A0A8V1ACP9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFF7/entry#A0A8V1ACP9-1", "sequence": { "sequence": "LNRWQRLRADTSRNTKRSDIQTPGVNRGRNGGSADSEASPQRRSLPGSSSPTRASEYAAINSMLDQISSCLDHLEEKNDHLHACLKELLESNRQTRLEFQQQSEQHSMGADMQGPQPPV", "length": 119, "header": "tr|A0A8V1ACP9-1|A0A8V1AFF7_CHICK Computationally mapped isoform of Bublin coiled coil protein OS=Gallus gallus OX=9031 GN=BBLN PE=4 SV=1 CANONICAL=A0A8V1AFF7-1" }, "locus": { "chromosome": "17", "start_pos": 5780203, "end_pos": 5777014, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068244.1", "url": "https://www.ensembl.org/id/ENSGALT00010068244.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041987.1", "url": "https://www.ensembl.org/id/ENSGALP00010041987.1" } ] } }, { "isoform_ac": "A0A8V1AFF7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFF7/entry#A0A8V1AFF7-1", "sequence": { "sequence": "MSGPNGDPHVALGPAGRDGGDEDGDGFGEEAINSMLDQISSCLDHLEEKNDHLHACLKELLESNRQTRLEFQQQSEQHSMGADMQGPQPPV", "length": 91, "header": "tr|A0A8V1AFF7-1|A0A8V1AFF7_CHICK Isoform 1 of Bublin coiled coil protein OS=Gallus gallus OX=9031 GN=BBLN PE=4 SV=1 CANONICAL=A0A8V1AFF7-1" }, "locus": { "chromosome": "17", "start_pos": 5778842, "end_pos": 5777014, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068241.1", "url": "https://www.ensembl.org/id/ENSGALT00010068241.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041984.1", "url": "https://www.ensembl.org/id/ENSGALP00010041984.1" } ] } }, { "isoform_ac": "A0A8V1AJM3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFF7/entry#A0A8V1AJM3-1", "sequence": { "sequence": "MSGPNGDPHVALGPAGRDGGDEDGDGFGEEEYAAINSMLDQISSCLDHLEEKNDHLHACLKELLESNRQTRLEFQQQSEQHSMGADMQGPQPPV", "length": 94, "header": "tr|A0A8V1AJM3-1|A0A8V1AFF7_CHICK Computationally mapped isoform of Bublin coiled coil protein OS=Gallus gallus OX=9031 GN=BBLN PE=4 SV=1 CANONICAL=A0A8V1AFF7-1" }, "locus": { "chromosome": "17", "start_pos": 5778842, "end_pos": 5777014, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068243.1", "url": "https://www.ensembl.org/id/ENSGALT00010068243.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041986.1", "url": "https://www.ensembl.org/id/ENSGALP00010041986.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:417215", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417215", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1QHR5-1", "protein_name": "Bublin coiled-coil protein", "gene_name": "bbln", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSGPNGDPDISAEGIIEDEDEFNEEEYAAIDSMLDQINSCLDDIEERNDALNGKLQELLESNRAARRDFRQQITDHADLPPPANDDEDEQSRDAQKKD", "length": 98 }, "evidence": [ { "id": "A0A8V1AFF7", "url": "https://omabrowser.org/oma/group/A0A8V1AFF7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "G3IBI8-1", "protein_name": "UPF0184 protein C9orf16 homolog isoform X2", "gene_name": "CUNH9orf16", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSGPNGDLGMPADAGAEGENDSFGEAEYAAINSMLDQINSCLDHLEEKNDHLHARLQELLESNRQTRLEFQQQLGEAPSDASP", "length": 83 }, "evidence": [ { "id": "A0A8V1AFF7", "url": "https://omabrowser.org/oma/group/A0A8V1AFF7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P58686-1", "protein_name": "Bublin coiled-coil protein", "gene_name": "Bbln", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSGPNGDLGMPVDAGTEGENDSFGEAEYAAINSMLDQINSCLDHLEEKNDHLHARLQELLESNRQTRLEFQQQLGEAPGDASP", "length": 83 }, "evidence": [ { "id": "A0A8V1AFF7", "url": "https://omabrowser.org/oma/group/A0A8V1AFF7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q2NKS9-1", "protein_name": "Bublin coiled-coil protein", "gene_name": "BBLN", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSGPNGDLGTPVEAGAEGEEDGFGEAEYAAINSMLDQINSCLDHLEEKNDHLHARLQELLESNRQTRLEFQQQLGETPSDASP", "length": 83 }, "evidence": [ { "id": "A0A8V1AFF7", "url": "https://omabrowser.org/oma/group/A0A8V1AFF7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q9BUW7-1", "protein_name": "Bublin coiled-coil protein", "gene_name": "BBLN", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSGPNGDLGMPVEAGAEGEEDGFGEAEYAAINSMLDQINSCLDHLEEKNDHLHARLQELLESNRQTRLEFQQQLGEAPSDASP", "length": 83 }, "evidence": [ { "id": "A0A8V1AFF7", "url": "https://omabrowser.org/oma/group/A0A8V1AFF7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AEZ8-1", "uniprot_ac": "A0A8V1AEZ8", "uniprot_id": "A0A8V1AEZ8_CHICK", "mass": { "chemical_mass": 37554.0, "monoisotopic_mass": 37554.0 }, "refseq": {}, "gene_names": [ { "name": "PLPP2", "type": "recommended", "evidence": [ { "id": "A0A8V1AEZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEZ8" } ] } ], "protein_names": [ { "name": "Phospholipid phosphatase 2", "type": "recommended", "evidence": [ { "id": "A0A8V1AEZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEZ8/entry#names_and_taxonomy" } ] }, { "name": "3.1.3.4", "type": "synonym", "evidence": [ { "id": "A0A8V1AEZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEZ8/entry#names_and_taxonomy" } ] }, { "name": "Lipid phosphate phosphohydrolase 2", "type": "synonym", "evidence": [ { "id": "A0A8V1AEZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEZ8/entry#names_and_taxonomy" } ] }, { "name": "PAP2-gamma", "type": "synonym", "evidence": [ { "id": "A0A8V1AEZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEZ8/entry#names_and_taxonomy" } ] }, { "name": "Phosphatidate phosphohydrolase type 2c", "type": "synonym", "evidence": [ { "id": "A0A8V1AEZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEZ8/entry#names_and_taxonomy" } ] }, { "name": "Phosphatidic acid phosphatase 2c", "type": "synonym", "evidence": [ { "id": "A0A8V1AEZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEZ8/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Magnesium-independent phospholipid phosphatase that catalyzes the dephosphorylation of a variety of glycerolipid and sphingolipid phosphate esters including phosphatidate/PA, lysophosphatidate/LPA, sphingosine 1-phosphate/S1P and ceramide 1-phosphate/C1P. Has no apparent extracellular phosphatase activity and therefore most probably acts intracellularly. Also acts on N-oleoyl ethanolamine phosphate/N-(9Z-octadecenoyl)-ethanolamine phosphate, a potential physiological compound. Through dephosphorylation of these bioactive lipid mediators produces new bioactive compounds and may regulate signal transduction in different cellular processes. Indirectly regulates, for instance, cell cycle G1/S phase transition through its phospholipid phosphatase activity.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACY1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACY1#function" }, { "database": "UniProtKB", "id": "ARBA00058757", "url": "https://www.uniprot.org/uniprotkb/ARBA00058757#function" }, { "database": "UniProtKB", "id": "A0A8V1AEZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEZ8#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEZ8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PLPP2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEZ8", "locus": { "chromosome": "28", "start_pos": 1629120, "end_pos": 1624885, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027154", "url": "https://www.ensembl.org/id/ENSGALG00010027154" } ] } } ], "crossref": [ { "id": "A0A8V1AEZ8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AEZ8", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd03384", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03384", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100858471", "url": "https://www.ncbi.nlm.nih.gov/gene/100858471", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000326", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000326", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036938", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036938", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043216", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043216", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:100858471", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100858471", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CWRWARL", "url": "https://omabrowser.org/oma/group/CWRWARL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ACY1", "url": "https://www.orthodb.org/?gene=A0A8V1ACY1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AEZ8", "url": "https://www.orthodb.org/?gene=A0A8V1AEZ8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10165", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10165", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10165:SF25", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10165:SF25", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01569", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01569", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-9845614", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9845614", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "27429", "url": "https://www.rhea-db.org/rhea/27429", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "27518", "url": "https://www.rhea-db.org/rhea/27518", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "33743", "url": "https://www.rhea-db.org/rhea/33743", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "43236", "url": "https://www.rhea-db.org/rhea/43236", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "43244", "url": "https://www.rhea-db.org/rhea/43244", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "46736", "url": "https://www.rhea-db.org/rhea/46736", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "50884", "url": "https://www.rhea-db.org/rhea/50884", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "62040", "url": "https://www.rhea-db.org/rhea/62040", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "62160", "url": "https://www.rhea-db.org/rhea/62160", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1ACY1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACY1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ACY1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACY1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AEZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEZ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AEZ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEZ8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLHGCPRAAISCGSSALQAAVSPDNALSAAGSALPWVQDPSPAVGSGDRGTVHTGCLHGVLGRVPQSSPSLSFAASLPFVILTLVNSPYKRGFYCNDDSIRYPYKADTITHGLMAGVTITCTVLIITSGEAYLVYTERLYSKSEYNNYLAALYKVVGTFLFGGAISQSLTDLAKYMIGRLRPNFLAVCNPDWSKVNCSIYVQLENVCRGESRNVTESRLSFYSGHSSFGMYCMMFLALYVQARLVGKWARLLRPTIQFFLLAFAIYVGYTRVSDYKHHWSDVLAGLLQGALIAILIVRYVSDFFKQRPPRQCDEKDPERKPSLPLTLSDTDRNHYSYAGAP", "length": 341, "header": "tr|A0A8V1AEZ8-1|A0A8V1AEZ8_CHICK Isoform 1 of Phospholipid phosphatase 2 OS=Gallus gallus OX=9031 GN=PLPP2 PE=3 SV=1 CANONICAL=A0A8V1AEZ8-1" }, "isoforms": [ { "isoform_ac": "A0A8V1ACY1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEZ8/entry#A0A8V1ACY1-1", "sequence": { "sequence": "MERRKVFVALDVLCVVVASLPFVILTLVNSPYKRGFYCNDDSIRYPYKADTITHGLMAGVTITCTVLIITSGEAYLVYTERLYSKSEYNNYLAALYKVVGTFLFGGAISQSLTDLAKYMIGRLRPNFLAVCNPDWSKVNCSIYVQLENVCRGESRNVTESRLSFYSGHSSFGMYCMMFLALYVQARLVGKWARLLRPTIQFFLLAFAIYVGYTRVSDYKHHWSDVLAGLLQGALIAILIVRYVSDFFKQRPPRQCDEKDPERKPSLPLTLSDTDRNHYSYAGAP", "length": 284, "header": "tr|A0A8V1ACY1-1|A0A8V1AEZ8_CHICK Computationally mapped isoform of Phospholipid phosphatase 2 OS=Gallus gallus OX=9031 GN=PLPP2 PE=3 SV=1 CANONICAL=A0A8V1AEZ8-1" }, "locus": { "chromosome": "28", "start_pos": 1628078, "end_pos": 1625011, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065832.1", "url": "https://www.ensembl.org/id/ENSGALT00010065832.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040098.1", "url": "https://www.ensembl.org/id/ENSGALP00010040098.1" } ] } }, { "isoform_ac": "A0A8V1AEZ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEZ8/entry#A0A8V1AEZ8-1", "sequence": { "sequence": "MLHGCPRAAISCGSSALQAAVSPDNALSAAGSALPWVQDPSPAVGSGDRGTVHTGCLHGVLGRVPQSSPSLSFAASLPFVILTLVNSPYKRGFYCNDDSIRYPYKADTITHGLMAGVTITCTVLIITSGEAYLVYTERLYSKSEYNNYLAALYKVVGTFLFGGAISQSLTDLAKYMIGRLRPNFLAVCNPDWSKVNCSIYVQLENVCRGESRNVTESRLSFYSGHSSFGMYCMMFLALYVQARLVGKWARLLRPTIQFFLLAFAIYVGYTRVSDYKHHWSDVLAGLLQGALIAILIVRYVSDFFKQRPPRQCDEKDPERKPSLPLTLSDTDRNHYSYAGAP", "length": 341, "header": "tr|A0A8V1AEZ8-1|A0A8V1AEZ8_CHICK Isoform 1 of Phospholipid phosphatase 2 OS=Gallus gallus OX=9031 GN=PLPP2 PE=3 SV=1 CANONICAL=A0A8V1AEZ8-1" }, "locus": { "chromosome": "28", "start_pos": 1628078, "end_pos": 1626630, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065830.1", "url": "https://www.ensembl.org/id/ENSGALT00010065830.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040096.1", "url": "https://www.ensembl.org/id/ENSGALP00010040096.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:100858471", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100858471", "resource": "KEGG Pathway" }, { "id": "R-GGA-9845614", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9845614", "resource": "Reactome", "description": "Sphingolipid catabolism" } ], "orthologs": [ { "uniprot_canonical_ac": "O43688-1", "protein_name": "Phospholipid phosphatase 2", "gene_name": "PLPP2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQRRWVFVLLDVLCLLVASLPFAILTLVNAPYKRGFYCGDDSIRYPYRPDTITHGLMAGVTITATVILVSAGEAYLVYTDRLYSRSDFNNYVAAVYKVLGTFLFGAAVSQSLTDLAKYMIGRLRPNFLAVCDPDWSRVNCSVYVQLEKVCRGNPADVTEARLSFYSGHSSFGMYCMVFLALYVQARLCWKWARLLRPTVQFFLVAFALYVGYTRVSDYKHHWSDVLVGLLQGALVAALTVCYISDFFKARPPQHCLKEEELERKPSLSLTLTLGEADHNHYGYPHSSS", "length": 288 }, "evidence": [ { "id": "A0A8V1AEZ8", "url": "https://omabrowser.org/oma/group/A0A8V1AEZ8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q2HJ61-1", "protein_name": "Phospholipid phosphatase 2", "gene_name": "PLPP2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MERRWVFVLLDVLCVLVAALPCAILTFVNTPYKRGFYCGDDSIRYPYRPDTITHGLMAGVIITATVILVSAGEAYLVYTDRLYSRSDFNNYLAALYKVVGTFLFGAAVSQSLTDLAKYMTGRLRPNFLAVCDPDWSRVNCSAYVQVEVCRGSSANVTESRLSFYSGHSSFGMYCMVFLALYVQARLCWKWARLLRPTVQFFLVAFALYVGYTRVSDHKHHWSDVLVGLLQGALVASLTVRYISDFFKARPPQHCPEEEDLERKPSLSLTLALGETDCNHYGYPVSSS", "length": 287 }, "evidence": [ { "id": "A0A8V1AEZ8", "url": "https://omabrowser.org/oma/group/A0A8V1AEZ8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8K593-1", "protein_name": "Phospholipid phosphatase 2", "gene_name": "Plpp2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MERRWVFVLLDVLCVLVASLPFIILTLVNAPYKRGFYCGDDSIRYPYRPDTITHGLMAGVIITATVVLVSSGEAYLVYTDRLYSRSDFNNYVAAIYKVLGTFLFGAAVSQSLTDLAKYMIGRLRPSFLAVCDPDWSRVNCSGYVQVEVCRGSPANVTEARLSFYSGHSSFGMYCMLFLALYVQARLCWKWARLLRPTVQFFLVAFAIYVGYTRVSDNKHHWSDVLVGLLQGALVACLTVCYVSDFFKSRPPQSCQENEESERKPSLSLTLTLGDRP", "length": 276 }, "evidence": [ { "id": "A0A8V1AEZ8", "url": "https://omabrowser.org/oma/group/A0A8V1AEZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9DAX2-1", "protein_name": "Phospholipid phosphatase 2", "gene_name": "Plpp2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MERRWVFVLLDVLCVLVASLPFIILTLVNAPYKRGFYCGDDSIRYPYRPDTITHGLMAGVIITATVILVSLGEAYLVYTDRLYSRSNFNNYVAAIYKVLGTFLFGAAVSQSLTDLAKYMIGRLRPSFLAVCDPDWSQVNCSGYVQLEVCRGSPANVTEARLSFYSGHSSFGMYCMLFLALYVQARLCWKWARLLRPTVQFFLVAFAIYVGYTRVSDHKHHWSDVLVGLLQGALVACLTVRYVSDFFKSRPPQPCQEDEVPERKPSLSLTLTLGDRP", "length": 276 }, "evidence": [ { "id": "A0A8V1AEZ8", "url": "https://omabrowser.org/oma/group/A0A8V1AEZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEZ8" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEZ8" } ], "pmid": "" }, { "name": "early endosome membrane", "id": "GO:0031901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031901", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEZ8" } ], "pmid": "" }, { "name": "caveola", "id": "GO:0005901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005901", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEZ8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "phospholipid metabolic process", "id": "GO:0006644", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006644", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEZ8" } ], "pmid": "" }, { "name": "sphingosine metabolic process", "id": "GO:0006670", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006670", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEZ8" } ], "pmid": "" }, { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEZ8" } ], "pmid": "" }, { "name": "ceramide metabolic process", "id": "GO:0006672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006672", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEZ8" } ], "pmid": "" }, { "name": "phospholipid dephosphorylation", "id": "GO:0046839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046839", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEZ8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "phosphatidate phosphatase activity", "id": "GO:0008195", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008195", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEZ8" } ], "pmid": "" }, { "name": "sphingosine-1-phosphate phosphatase activity", "id": "GO:0042392", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042392", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEZ8" } ], "pmid": "" }, { "name": "ceramide-1-phosphate phosphatase activity", "id": "GO:0106235", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106235", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEZ8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 196, "end_pos": 198, "annotation": "n_glycosylation_sequon" }, { "start_pos": 213, "end_pos": 215, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "27429", "name": "", "equation": "a 1,2-diacyl-sn-glycero-3-phosphate + H2O = a 1,2-diacyl-sn-glycerol + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XEH7-1", "A0A8V0XAG3-1", "A0A1D5NZW4-1", "A0A8V0XAH3-1", "E1C944-1", "A0A8V1AEZ8-1" ], "evidence": [ { "id": "27429", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/27429" } ] }, { "id": "27518", "name": "", "equation": "sphing-4-enine 1-phosphate + H2O = sphing-4-enine + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A1D5NZW4-1", "E1C944-1", "A0A8V1AEZ8-1" ], "evidence": [ { "id": "27518", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/27518" } ] }, { "id": "33743", "name": "", "equation": "an N-acylsphing-4-enine 1-phosphate + H2O = an N-acylsphing-4-enine + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A1D5NZW4-1", "E1C944-1", "A0A8V1AEZ8-1" ], "evidence": [ { "id": "33743", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/33743" } ] }, { "id": "43236", "name": "", "equation": "1,2-dihexadecanoyl-sn-glycero-3-phosphate + H2O = 1,2-dihexadecanoyl-sn-glycerol + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A1D5NZW4-1", "E1C944-1", "A0A8V1AEZ8-1" ], "evidence": [ { "id": "43236", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/43236" } ] }, { "id": "43244", "name": "", "equation": "1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphate + H2O = 1,2-di-(9Z-octadecenoyl)-sn-glycerol + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A1D5NZW4-1", "E1C944-1", "A0A8V1AEZ8-1" ], "evidence": [ { "id": "43244", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/43244" } ] }, { "id": "46736", "name": "", "equation": "a monoacyl-sn-glycero-3-phosphate + H2O = a monoacylglycerol + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A1D5NZW4-1", "E1C944-1", "A0A8V1AEZ8-1" ], "evidence": [ { "id": "46736", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/46736" } ] }, { "id": "50884", "name": "", "equation": "(9Z)-octadecenoyl-sn-glycero-3-phosphate + H2O = (9Z-octadecenoyl)-glycerol + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A1D5NZW4-1", "E1C944-1", "A0A8V1AEZ8-1" ], "evidence": [ { "id": "50884", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/50884" } ] }, { "id": "62040", "name": "", "equation": "N-(octanoyl)-sphing-4-enine-1-phosphate + H2O = N-octanoylsphing-4-enine + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A1D5NZW4-1", "E1C944-1", "A0A8V1AEZ8-1" ], "evidence": [ { "id": "62040", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/62040" } ] }, { "id": "62160", "name": "", "equation": "N-(9Z-octadecenoyl)-ethanolamine phosphate + H2O = N-(9Z-octadecenoyl) ethanolamine + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A1D5NZW4-1", "E1C944-1", "A0A8V1AEZ8-1" ], "evidence": [ { "id": "62160", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/62160" } ] }, { "id": "R-GGA-428696", "name": "PLPP1,2,3 dephosphorylate cytosolic sphingosine-1-phosphate", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1C944-1", "A0A8V1AEZ8-1", "A0A1D5NZW4-1" ], "evidence": [ { "id": "R-GGA-428696", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-428696" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5NZW4", "gene_name": "PLPP1", "activity": [ { "ec_number": "3.1.3.4", "activity": "1-O-alkyl-2-acyl-sn-glycero-3-phosphate + H2O = 1-O-alkyl-2-acyl-sn-glycerol + phosphate.", "evidence": [ { "id": "A0A1D5NZW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZW4" } ] }, { "ec_number": "3.1.3.106", "activity": "a 1-acyl-sn-glycero-3-phosphate + H2O = a 1-acyl-sn-glycerol + phosphate.", "evidence": [ { "id": "A0A1D5NZW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZW4" } ] }, { "ec_number": "3.6.1.75", "activity": "a 1,2-diacyl-sn-glycerol 3-diphosphate + H2O = a 1,2-diacyl-sn-glycero-3-phosphate + phosphate + H(+).", "evidence": [ { "id": "A0A1D5NZW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZW4" } ] }, { "ec_number": "3.1.3.106", "activity": "", "evidence": [ { "id": "A0A1D5NZW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZW4" } ] }, { "ec_number": "3.1.3.4", "activity": "", "evidence": [ { "id": "A0A1D5NZW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZW4" } ] }, { "ec_number": "3.6.1.75", "activity": "", "evidence": [ { "id": "A0A1D5NZW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZW4" } ] } ] }, { "uniprot_ac": "A0A8V0XAG3", "gene_name": "LPIN2", "activity": [ { "ec_number": "3.1.3.4", "activity": "1-O-alkyl-2-acyl-sn-glycero-3-phosphate + H2O = 1-O-alkyl-2-acyl-sn-glycerol + phosphate.", "evidence": [ { "id": "A0A8V0XAG3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XAG3" } ] }, { "ec_number": "3.1.3.4", "activity": "", "evidence": [ { "id": "A0A8V0XAG3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XAG3" } ] } ] }, { "uniprot_ac": "A0A8V0XAH3", "gene_name": "PLPP4", "activity": [ { "ec_number": "3.1.3.4", "activity": "1-O-alkyl-2-acyl-sn-glycero-3-phosphate + H2O = 1-O-alkyl-2-acyl-sn-glycerol + phosphate.", "evidence": [ { "id": "A0A8V0XAH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XAH3" } ] }, { "ec_number": "3.6.1.75", "activity": "a 1,2-diacyl-sn-glycerol 3-diphosphate + H2O = a 1,2-diacyl-sn-glycero-3-phosphate + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XAH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XAH3" } ] }, { "ec_number": "3.1.3.4", "activity": "", "evidence": [ { "id": "A0A8V0XAH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XAH3" } ] }, { "ec_number": "3.6.1.75", "activity": "", "evidence": [ { "id": "A0A8V0XAH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XAH3" } ] } ] }, { "uniprot_ac": "A0A8V0XEH7", "gene_name": "LPIN1", "activity": [ { "ec_number": "3.1.3.4", "activity": "1-O-alkyl-2-acyl-sn-glycero-3-phosphate + H2O = 1-O-alkyl-2-acyl-sn-glycerol + phosphate.", "evidence": [ { "id": "A0A8V0XEH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEH7" } ] }, { "ec_number": "3.1.3.4", "activity": "", "evidence": [ { "id": "A0A8V0XEH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEH7" } ] } ] }, { "uniprot_ac": "A0A8V1AEZ8", "gene_name": "PLPP2", "activity": [ { "ec_number": "3.1.3.4", "activity": "1-O-alkyl-2-acyl-sn-glycero-3-phosphate + H2O = 1-O-alkyl-2-acyl-sn-glycerol + phosphate.", "evidence": [ { "id": "A0A8V1AEZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEZ8" } ] }, { "ec_number": "3.1.3.4", "activity": "", "evidence": [ { "id": "A0A8V1AEZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEZ8" } ] } ] }, { "uniprot_ac": "E1C944", "gene_name": "PLPP3", "activity": [ { "ec_number": "3.1.3.4", "activity": "1-O-alkyl-2-acyl-sn-glycero-3-phosphate + H2O = 1-O-alkyl-2-acyl-sn-glycerol + phosphate.", "evidence": [ { "id": "E1C944", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C944" } ] }, { "ec_number": "3.1.3.4", "activity": "", "evidence": [ { "id": "E1C944", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C944" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AEZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEZ8" }, { "id": "SM00014", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00014" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Phosphatidic acid phosphatase type 2/haloperoxidase", "eco_id": "ECO_0000259", "start_pos": 156, "end_pos": 297, "start_aa": "Val", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.1.3.4", "ec_name": "1-O-alkyl-2-acyl-sn-glycero-3-phosphate + H2O = 1-O-alkyl-2-acyl-sn-glycerol + phosphate.", "evidence": [ { "id": "3.1.3.4", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.4" }, { "id": "3.1.3.4", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.1.3.4" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 196, "end_pos": 198 }, { "start_pos": 213, "end_pos": 215 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AFL9-1", "uniprot_ac": "A0A8V1AFL9", "uniprot_id": "A0A8V1AFL9_CHICK", "mass": { "chemical_mass": 45030.0, "monoisotopic_mass": 45030.0 }, "refseq": { "ac": "XP_015148570", "name": "transmembrane protein adipocyte-associated 1 homolog isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015148570" }, "gene_names": [ { "name": "TPRA1", "type": "recommended", "evidence": [ { "id": "A0A8V1AFL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFL9" } ] }, { "name": "GPR175", "type": "synonym", "evidence": [ { "id": "XP_015148570", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015148570" } ] }, { "name": "TPRA1", "type": "synonym", "evidence": [ { "id": "XP_015148570", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015148570" } ] } ], "protein_names": [ { "name": "Integral membrane protein GPR175", "type": "recommended", "evidence": [ { "id": "A0A8V1AFL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFL9/entry#names_and_taxonomy" } ] }, { "name": "transmembrane protein adipocyte-associated 1 homolog isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015148570", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015148570" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052543.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015148570.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015148570", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015148570" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFL9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFL9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TPRA1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFL9", "locus": { "chromosome": "12", "start_pos": 9949232, "end_pos": 9933388, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028187", "url": "https://www.ensembl.org/id/ENSGALG00010028187" } ] } } ], "crossref": [ { "id": "A0A8V1AFL9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AFL9", "database": "AlphaFoldDB", "categories": [] }, { "id": "416028", "url": "https://www.ncbi.nlm.nih.gov/gene/416028", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR018781", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018781", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416028", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416028", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DRWKSIN", "url": "https://omabrowser.org/oma/group/DRWKSIN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ACY2", "url": "https://www.orthodb.org/?gene=A0A8V1ACY2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AFL9", "url": "https://www.orthodb.org/?gene=A0A8V1AFL9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AHY3", "url": "https://www.orthodb.org/?gene=A0A8V1AHY3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AJT0", "url": "https://www.orthodb.org/?gene=A0A8V1AJT0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15876", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15876", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15876:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15876:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10160", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10160", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015148570", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015148570", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1ACY2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACY2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ACY2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACY2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFL9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFL9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFL9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFL9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHY3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHY3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHY3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHY3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJT0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJT0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJT0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJT0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKHEEFNGEQFLFIFSRRQDIPVMMSMMRFSMSDNITRSTALVTALDNVTTLSPTTTQAINDTNITVPHKCLLLLYEDIGKSRVRYWDLLLLVPNVLFFMFLLWKLPSARAKIRVTSSPIFTTFYILVFVVALVGIARAVVSMTVSASDAATVADKILWEITRFFLLAIELSVVILGLAFGHLESKSSVKRVLAITTVLSLAYSVTQGTLEILYPDAHLSAEDFNIYGHGGRHFWLASSCFFFLVYSFVVILPKTPLKDRISLPSRKSFYVYAGILAVLNLVQGLGSALLCVDIIEGLCCVDATTFLYFSFFAPLIYVAFLKGFFGSEPKILFSYKCQVDEPEDVDVHLPHAYAVAKKEGMDSGFYSSTQIDTTAYLDDVASMPYHVGSINSIDSDRWKAINA", "length": 403, "header": "tr|A0A8V1AFL9-1|A0A8V1AFL9_CHICK Isoform 1 of Integral membrane protein GPR175 OS=Gallus gallus OX=9031 GN=TPRA1 PE=3 SV=1 CANONICAL=A0A8V1AFL9-1" }, "isoforms": [ { "isoform_ac": "A0A8V1ACY2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFL9/entry#A0A8V1ACY2-1", "sequence": { "sequence": "MMSMMRFSMSDNITRSTALVTALDNVTTLSPTTTQAINDTNITVPHKCLLLLYEDIGKVRYWDLLLLVPNVLFFMFLLWKLPSARAKIRVTSSPIFTTFYILVFVVALVGIARAVVSMTVSASDAATVADKILWEITRFFLLAIELSVVILGLAFGHLESKSSVKRVLAITTVLSLAYSVTQGTLEILYPDAHLSAEDFNIYGHGGRHFWLASSCFFFLVYSFVVILPKTPLKDRISLPSRKSFYVYAGILAVLNLVQGLGSALLCVDIIEGLCCVDATTFLYFSFFAPLIYVAFLKGFFGSEPKILFSYKCQVDEPEDVDVHLPHAYAVAKKEGMDSGFYSSTQIDTTAYLDDVASMPYHVGSINSIDSDRWKAINA", "length": 378, "header": "tr|A0A8V1ACY2-1|A0A8V1AFL9_CHICK Computationally mapped isoform of Integral membrane protein GPR175 OS=Gallus gallus OX=9031 GN=TPRA1 PE=3 SV=1 CANONICAL=A0A8V1AFL9-1" }, "locus": { "chromosome": "12", "start_pos": 9946740, "end_pos": 9937574, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068310.1", "url": "https://www.ensembl.org/id/ENSGALT00010068310.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042053.1", "url": "https://www.ensembl.org/id/ENSGALP00010042053.1" } ] } }, { "isoform_ac": "A0A8V1AFL9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFL9/entry#A0A8V1AFL9-1", "sequence": { "sequence": "MKHEEFNGEQFLFIFSRRQDIPVMMSMMRFSMSDNITRSTALVTALDNVTTLSPTTTQAINDTNITVPHKCLLLLYEDIGKSRVRYWDLLLLVPNVLFFMFLLWKLPSARAKIRVTSSPIFTTFYILVFVVALVGIARAVVSMTVSASDAATVADKILWEITRFFLLAIELSVVILGLAFGHLESKSSVKRVLAITTVLSLAYSVTQGTLEILYPDAHLSAEDFNIYGHGGRHFWLASSCFFFLVYSFVVILPKTPLKDRISLPSRKSFYVYAGILAVLNLVQGLGSALLCVDIIEGLCCVDATTFLYFSFFAPLIYVAFLKGFFGSEPKILFSYKCQVDEPEDVDVHLPHAYAVAKKEGMDSGFYSSTQIDTTAYLDDVASMPYHVGSINSIDSDRWKAINA", "length": 403, "header": "tr|A0A8V1AFL9-1|A0A8V1AFL9_CHICK Isoform 1 of Integral membrane protein GPR175 OS=Gallus gallus OX=9031 GN=TPRA1 PE=3 SV=1 CANONICAL=A0A8V1AFL9-1" }, "locus": { "chromosome": "12", "start_pos": 9946740, "end_pos": 9936506, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068307.1", "url": "https://www.ensembl.org/id/ENSGALT00010068307.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042050.1", "url": "https://www.ensembl.org/id/ENSGALP00010042050.1" } ] } }, { "isoform_ac": "A0A8V1AHY3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFL9/entry#A0A8V1AHY3-1", "sequence": { "sequence": "MLSRRQDIPVMMSMMRFSMSDNITRSTALVTALDNVTTLSPTTTQAINDTNITVPHKCLLLLYEDIGKSRVRYWDLLLLVPNVLFFMFLLWKLPSARAKIRVTSSPIFTTFYILVFVVALVGIARAVVSMTVSASDAATVADKILWEITRFFLLAIELSVVILGLAFGHLESKSSVKRVLAITTVLSLAYSVTQGTLEILYPDAHLSAEDFNIYGHGGRHFWLASSCFFFLVYSFVVILPKTPLKDRISLPSRKSFYVYAGILAVLNLVQGLGSALLCVDIIEGLCCVDATTFLYFSFFAPLIYVAFLKGFFGSEPKILFSYKCQVDEPEDVDVHLPHAYAVAKKEGMDSGFYSSTQIDTTAYLDDVASMPYHVGSINSIDSDRWKAINA", "length": 390, "header": "tr|A0A8V1AHY3-1|A0A8V1AFL9_CHICK Computationally mapped isoform of Integral membrane protein GPR175 OS=Gallus gallus OX=9031 GN=TPRA1 PE=3 SV=1 CANONICAL=A0A8V1AFL9-1" }, "locus": { "chromosome": "12", "start_pos": 9946740, "end_pos": 9935430, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068311.1", "url": "https://www.ensembl.org/id/ENSGALT00010068311.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042054.1", "url": "https://www.ensembl.org/id/ENSGALP00010042054.1" } ] } }, { "isoform_ac": "A0A8V1AJT0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFL9/entry#A0A8V1AJT0-1", "sequence": { "sequence": "MMSMMRFSMSDNITRSTALVTALDNVTTLSPTTTQAINDTNITVPHKCLLLLYEDIGKSRVRYWDLLLLVPNVLFFMFLLWKLPSARAKIRVTSSPIFTTFYILVFVVALVGIARAVVSMTVSASDAATVADKILWEITRFFLLAIELSVVILGLAFGHLESKSSVKRVLAITTVLSLAYSVTQGTLEILYPDAHLSAEDFNIYGHGGRHFWLASSCFFFLVYSFVVILPKTPLKDRISLPSRKSFYVYAGILAVLNLVQGLGSALLCVDIIEGLCCVDATTFLYFSFFAPLIYVAFLKGFFGSEPKILFSYKCQVDEPEDVDVHLPHAYAVAKKEGMDSGFYSSTQIDTTAYLDDVASMPYHVGSINSIDSDRWKAINA", "length": 380, "header": "tr|A0A8V1AJT0-1|A0A8V1AFL9_CHICK Computationally mapped isoform of Integral membrane protein GPR175 OS=Gallus gallus OX=9031 GN=TPRA1 PE=3 SV=1 CANONICAL=A0A8V1AFL9-1" }, "locus": { "chromosome": "12", "start_pos": 9946740, "end_pos": 9937574, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068309.1", "url": "https://www.ensembl.org/id/ENSGALT00010068309.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042052.1", "url": "https://www.ensembl.org/id/ENSGALP00010042052.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:416028", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416028", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2QC63-1", "protein_name": "Integral membrane protein GPR175", "gene_name": "Tpra1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDSLQEANGSTAWPPPTASNRPPTASNISEPHQCLLLLYEDIGSSRVRYWDLLLLIPNVLFFIFLLWKLPLARAKIRVTSSPIFITFYILVFVVALVGIARAVVSMTVSASDAATIADKILWEITRFFLLAIELSVIILGLAFGHLESKSSIKRVLAITTVLSLAYSVTQGTLEILYPDSHLSAEDFNIYGHGGRQFWLVSSCFFFLVYSLVVILPKTPLKERVSLPSRRSFYVYAGILATLNLLQGLGSALLCANIIEGLCCVDATTFLYFSFFAPLIYVAFLRGFFGSEPKILFSYKCQVDEAEEPDMHLPQPYAVARREGIESTGPAGVSAASYSSTQFDSAGMAYLDDIASMPCHTGSINSTDSERWKAINA", "length": 376 }, "evidence": [ { "id": "A0A8V1AFL9", "url": "https://omabrowser.org/oma/group/A0A8V1AFL9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "F1SPF4-1", "protein_name": "Integral membrane protein GPR175", "gene_name": "TPRA1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGGRGLRTGCWRDGHPGGGDLGQQSMALPPPLAPNISVPHRCLLLLYEDIGTSRVRYWDLLLLIPNVLFFIFLLWKLPFARAKIRVTSSPIFITFYILVFVVALVGIARAVVSMTVSTSDAATVADKILWEITRFFLLAIELSVVILGLAFGHLESKSSIKRVLAITTVLSLAYSVTQGTLEILYPDAHLSAEDFNIYGHGGRQFWLVSSCFFFLVYSLVVVLPKTPLKERISLPSRRSFYVYAGILALLNLLQGLGSALLCADIIEGLCCVDATTFLYFSFFAPLIYVAFLRGFFGSEPKILFSYKCQVDEAEEPDMHLPQPYAVARREGLEAAGAASTQFDSASGVAYLDDVASMPCHAGSINSTDSERWKAINA", "length": 377 }, "evidence": [ { "id": "A0A8V1AFL9", "url": "https://omabrowser.org/oma/group/A0A8V1AFL9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q4V8X0-1", "protein_name": "Transmembrane protein adipocyte-associated 1 homolog", "gene_name": "tpra1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLETVTDVASFVHYGNTSVFPTADNSSEIIPDGESNISKPHRCLQVLYDDIGTSRVRYWDVMLLIPNVAFLVFLMWKLPSARAKIRLTSSPIFVAFYILVFVVAAVGITRAIVSMTVSTSSAATLIDKVLWEITRFFLLAIELSVIILGLAFGHLESKSSIKRVLAITAVLSLAYSITQGTLEIRFPDKHLSAKDFNIYGHGGRHFWLASSCFFFLVYSLIVILPKTPIRERISLPSKRSFYVYSGILALLNLVQGLGSALLCADIIEGLCCVDVTTFLYFSVFAPLIYVTFLKGFFGSEPKILFSYKSQIDEPEDSDVHLPHTSSSGLGRKDLDRGSYSSTQIDGSGAYLDDVVSGPFGGAHSINSVDSDRWRSINT", "length": 378 }, "evidence": [ { "id": "A0A8V1AFL9", "url": "https://omabrowser.org/oma/group/A0A8V1AFL9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q791F6-1", "protein_name": "Transmembrane protein adipocyte-associated 1", "gene_name": "Tpra1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASLQEANGSTAWPPPTASNISEPHQCLLLLYEDIGSSRVRYWDLLLLIPNVLFFIFLLWKLPLARAKIRVTSSPIFITFYILVFVVALVGIARAVVSMTVSASDAATVADKILWEITRFFLLAIELSVIILGLAFGHLESKSSIKRVLAITTVLSLAYSVTQGTLEILYPDSHLSAEDFNIYGHGGRQFWLVSSCFFFLVYSLVVILPKTPLKERVSLPSRRSFYVYAGILATLNLLQGLGSALLCANIIVGLCCVDATTFLYFSFFAPLIYVAFLRGFFGSEPKILFSYKCQVDEAEEPDMHLPQPYAVARREGIESAGPACASAANYSSTQFDSAGVAYLDDIASMPCHTGSINSTDSERWKAINA", "length": 369 }, "evidence": [ { "id": "A0A8V1AFL9", "url": "https://omabrowser.org/oma/group/A0A8V1AFL9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q86W33-1", "protein_name": "Transmembrane protein adipocyte-associated 1", "gene_name": "TPRA1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDTLEEVTWANGSTALPPPLAPNISVPHRCLLLLYEDIGTSRVRYWDLLLLIPNVLFLIFLLWKLPSARAKIRITSSPIFITFYILVFVVALVGIARAVVSMTVSTSNAATVADKILWEITRFFLLAIELSVIILGLAFGHLESKSSIKRVLAITTVLSLAYSVTQGTLEILYPDAHLSAEDFNIYGHGGRQFWLVSSCFFFLVYSLVVILPKTPLKERISLPSRRSFYVYAGILALLNLLQGLGSVLLCFDIIEGLCCVDATTFLYFSFFAPLIYVAFLRGFFGSEPKILFSYKCQVDETEEPDVHLPQPYAVARREGLEAAGAAGASAASYSSTQFDSAGGVAYLDDIASMPCHTGSINSTDSERWKAINA", "length": 373 }, "evidence": [ { "id": "A0A8V1AFL9", "url": "https://omabrowser.org/oma/group/A0A8V1AFL9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q94AH1-1", "protein_name": "Protein CANDIDATE G PROTEIN-COUPLED RECEPTOR 2", "gene_name": "CAND2", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MRVLSEIAESPFVISRLSPDSTATGGFIGGWVGKCHGFLHNTVLVLASILFVAYLAYEAKKSLSKLSNRRSYIMIAYYGFLWLVSLLNLAWCCLQAWECTPGKEVIWNLLTLFTTSGMLFLEVSLVAFLFQGNYASGAEALTRTFLISGLVIGLDLLLKAIYLFGFGVPLFIDNNEHIHKFKWGLWVIHKLLLAGIYGMIFFMYNSKWRERLPARPAFYKYITVMLALNGLSLFACALTANGAHFGLWLYGITSVCYHAFYLPLLYVTFLADFFQEEDLNLENVYYSEMKDAGFFDADWE", "length": 300 }, "evidence": [ { "id": "A0A8V1AFL9", "url": "https://omabrowser.org/oma/group/A0A8V1AFL9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q99MU1-1", "protein_name": "Transmembrane protein adipocyte-associated 1", "gene_name": "Tpra1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASLQEANGSTAWPPPTASNISEPHQCLLLLYEDIGSSRVRYWDLLLLIPNVLFFIFLLWKLPLARAKIRVTSSPIFITFYILVFVVALVGIARAVVSMTVSASDAATVADKILWEITRFFLLAIELSVIILGLAFGHLESKSSIKRVLAITTVLSLAYSVTQGTLEILYPDSHLSAEDFNIYGHGGRQFWLVSSCFFFLVYSLVVILPKTPLKERVSLPSRRSFYVYAGILATLNLLQGLGSALLCANIIVGLCCVDATTFLYFSFFAPLIYVAFLRGFFGSEPKILFSYKCQVDEAEEPDMHLPQPYAVARREGIESAGPACASAANYSSTQFDSAGVAYLDDIASMPCHTGSINSTDSERWKAINA", "length": 369 }, "evidence": [ { "id": "A0A8V1AFL9", "url": "https://omabrowser.org/oma/group/A0A8V1AFL9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFL9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFL9" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFL9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFL9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFL9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFL9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "G protein-coupled receptor signaling pathway", "id": "GO:0007186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007186", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFL9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFL9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 35, "end_pos": 37, "annotation": "n_glycosylation_sequon" }, { "start_pos": 48, "end_pos": 50, "annotation": "n_glycosylation_sequon" }, { "start_pos": 61, "end_pos": 63, "annotation": "n_glycosylation_sequon" }, { "start_pos": 64, "end_pos": 66, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 35, "end_pos": 37 }, { "start_pos": 48, "end_pos": 50 }, { "start_pos": 61, "end_pos": 63 }, { "start_pos": 64, "end_pos": 66 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AFA1-1", "uniprot_ac": "A0A8V1AFA1", "uniprot_id": "A0A8V1AFA1_CHICK", "mass": { "chemical_mass": 54128.0, "monoisotopic_mass": 54128.0 }, "refseq": {}, "gene_names": [ { "name": "CAMK1G", "type": "recommended", "evidence": [ { "id": "A0A8V1AFA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFA1" } ] } ], "protein_names": [ { "name": "Calcium/calmodulin-dependent protein kinase type 1G", "type": "recommended", "evidence": [ { "id": "A0A8V1AFA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFA1/entry#names_and_taxonomy" } ] }, { "name": "CaM kinase I gamma", "type": "synonym", "evidence": [ { "id": "A0A8V1AFA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFA1/entry#names_and_taxonomy" } ] }, { "name": "CaMK-like CREB kinase III", "type": "synonym", "evidence": [ { "id": "A0A8V1AFA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFA1/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Calcium/calmodulin-dependent protein kinase belonging to a proposed calcium-triggered signaling cascade. In vitro phosphorylates transcription factor CREB1.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFA1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFA1#function" }, { "database": "UniProtKB", "id": "ARBA00060242", "url": "https://www.uniprot.org/uniprotkb/ARBA00060242#function" }, { "database": "UniProtKB", "id": "A0A8V1AD79", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD79#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFA1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFA1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CAMK1G", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFA1", "locus": { "chromosome": "26", "start_pos": 3150177, "end_pos": 3138212, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027193", "url": "https://www.ensembl.org/id/ENSGALG00010027193" } ] } } ], "crossref": [ { "id": "A0A8V1AFA1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AFA1", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd14166", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14166", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008271", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008271", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017441", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017441", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AD79", "url": "https://www.orthodb.org/?gene=A0A8V1AD79", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AFA1", "url": "https://www.orthodb.org/?gene=A0A8V1AFA1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24347", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24347", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00069", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00069", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1AD79", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD79", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AD79-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD79-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFA1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFA1", "database": "UniProtKB", "categories": [ "Protein" ] }, { 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"MGRKEEDDSSSWKKQTSNIRKTFIFMEALGSGAFSEVFLVKQRSTGKLFALKCIKKSPLTRDSSLENEIAVLKKIKHENIVTLEDIYESTTHFYLVMQLVSGGELFDRILERGVYTEKDASVVIHQVLTAVKYLHENGIVHRDLKPENLLYLTPEENSKIMITDFGLSKMEQNGIMSTACGTPGYVAPEVLAQKPYSKAVDCWSIGVITYILLCGYPPFYEETESKLFEKIKEGYYEFESPFWDDISDSAKDFIRHLLEKNPDTRFSCEEALRHPWINGNTALHRDIYPSVSTQIQKNFAKSKWRQAFNAAAVVHHMRKLHMNGHAAAGSTHPIIQGSEAPRPSTPDTTQPAMPSKDEDMSLPQVPCPAPPAPLEEGTGMREGKLQSPPVNGSPDNQSPPARSCGCSPVCTGHERAKASFCSETVLLKKPAKSQ", "length": 434, "header": "tr|A0A8V1AD79-1|A0A8V1AFA1_CHICK Computationally mapped isoform of Calcium/calmodulin-dependent protein kinase type 1G OS=Gallus gallus OX=9031 GN=CAMK1G PE=3 SV=1 CANONICAL=A0A8V1AFA1-1" }, "locus": { "chromosome": "26", "start_pos": 3148068, "end_pos": 3142227, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065932.1", "url": "https://www.ensembl.org/id/ENSGALT00010065932.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040198.1", "url": "https://www.ensembl.org/id/ENSGALP00010040198.1" } ] } }, { "isoform_ac": "A0A8V1AFA1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFA1/entry#A0A8V1AFA1-1", "sequence": { "sequence": "MPAPTAALSSLPLSPAAFPASTLEEMGRKEEDDSSSWKKQTSNIRKTFIFMEALGSGAFSEVFLVKQRSTGKLFALKCIKKSPLTRDSSLENEIAVLKKIKHENIVTLEDIYESTTHFYLVMQLVSGGELFDRILERGVYTEKDASVVIHQVLTAVKYLHENGIVHRDLKPENLLYLTPEENSKIMITDFGLSKMEQNGIMSTACGTPGYVAPEVLAQKPYSKAVDCWSIGVITYILLCGYPPFYEETESKLFEKIKEGYYEFESPFWDDISDSAKDFIRHLLEKNPDTRFSCEEALRHPWINGNTALHRDIYPSVSTQIQKNFAKSKWRQAFNAAAVVHHMRKLHMNGHAAAGSTHPIIQGSEAPRPSTPDTTQPAMPSKDEDMSLPQVPCPAPPAPLEEGTGMREGKLQSPPVNGSPDNQSPPARSCGCSPVCTGHERAKASFCSETVLLKKPAKSHHFKSEVLVPMKTGKHSSHCGTGQTGVCLIM", "length": 489, "header": "tr|A0A8V1AFA1-1|A0A8V1AFA1_CHICK Isoform 1 of Calcium/calmodulin-dependent protein kinase type 1G OS=Gallus gallus OX=9031 GN=CAMK1G PE=3 SV=1 CANONICAL=A0A8V1AFA1-1" }, "locus": { "chromosome": "26", "start_pos": 3148677, "end_pos": 3142152, "strand": "-", "evidence": [ { "database": 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], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "calmodulin binding", "id": "GO:0005516", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005516", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFA1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFA1" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFA1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFA1" } ], "pmid": "" }, { "name": "calcium/calmodulin-dependent protein kinase activity", "id": "GO:0004683", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004683", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFA1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFA1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFA1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFA1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 416, "end_pos": 418, "annotation": "n_glycosylation_sequon" }, { "start_pos": 421, "end_pos": 423, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AFA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFA1" }, { "id": "PS50011", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50011" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Protein kinase", "eco_id": "ECO_0000259", "start_pos": 48, "end_pos": 302, "start_aa": "Phe", "end_aa": "Ile", "glycosite_overlap": "" } ], 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"sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AEY0-1", "uniprot_ac": "A0A8V1AEY0", "uniprot_id": "A0A8V1AEY0_CHICK", "mass": { "chemical_mass": 40292.0, "monoisotopic_mass": 40292.0 }, "refseq": {}, "gene_names": [ { "name": "GABPB2", "type": "recommended", "evidence": [ { "id": "A0A8V1AEY0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEY0" } ] } ], "protein_names": [ { "name": "GA binding protein transcription factor subunit beta 2", "type": "synonym", "evidence": [ { "id": "A0A8V1AEY0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEY0/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEY0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEY0" } ], "common_name": "Chicken", "glygen_name": "Chicken", 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"protein_names": [ { "name": "tRNA splicing endonuclease subunit 54", "type": "synonym", "evidence": [ { "id": "A0A8V1AEY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEY4/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEY4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEY4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TSEN54", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEY4", "locus": { "chromosome": "18", "start_pos": 11526252, "end_pos": 11517213, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029725", "url": "https://www.ensembl.org/id/ENSGALG00010029725" } ] } } ], "crossref": [ { "id": "A0A8V1AEY4", "url": 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"Protein" ] }, { "id": "A0A8V1ALX5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALX5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEPGCSRYLRRSRASWRSCGQKEFVPDGSTEQAERLRLCLEEQWRQLAEERVERPGNLVKAVWKPEQSVVELESPAGKFWHTMGFSERGKQCLLPEEALYLLECGSLQLFYKDVPMSVREAYEILLSQEAMNLLHYQVFSHLKQLGFIVLRFNPSTVLSPYERQLNLESHCKSSGKHHHKRRRSSSPGSCEKKHKVSEDLPKAEGTCEKGGDDCGEFSCIPLDEKPLSEQLKELDTGNGEEQSVTSNSVPLDTGRKNAPRLSWSLGTGDQKASSTGTRVPHWDFTTIFLPNVASDQPCIHLPAPDSKLLPENVPGREVDAASWCRRINQKQERLTQKEREQWERESKYKSSISADREVRCCMNWQEYKALLRWRSQQRVWRQPLHPWDQAVTPLLQPEEATSLAAVRQQISVLQPSHILDGASWLQEDLESIKIDFNVYQADAVAKFKKTNPGKPYVRMCVQSERSPKCLLSLPGLQLVCSKPRMSLLSRPFHVSLPPSYPGTKFALASMQKYQCQVPESLLSGY", "length": 525, "header": "tr|A0A8V1AEY4-1|A0A8V1AEY4_CHICK Isoform 1 of tRNA splicing endonuclease subunit 54 OS=Gallus gallus OX=9031 GN=TSEN54 PE=1 SV=1 CANONICAL=A0A8V1AEY4-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AEY4-1", "url": 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"https://www.ensembl.org/id/ENSGALT00010071904.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044594.1", "url": "https://www.ensembl.org/id/ENSGALP00010044594.1" } ] } }, { "isoform_ac": "A0A8V1ALX5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEY4/entry#A0A8V1ALX5-1", "sequence": { "sequence": "MEPGCSRYLRRSRASWRSCGQKEFVPDGSTEQAERLRLCLEEQWRQLAEERVERPGNLVKAVWKPEQSVVELESPAGKFWHTMGFSERGKQCLLPEEALYLLECGSLQLFYKDVPMSVREAYEILLSQEAMNLLHYQVFSHLKQLGFIVLRFNPSTVLSPYERQLNLESHCKSSGKHHHKRRRSSSPGSCEKKHKVSEDLPKAEGTCEKGGDDCGEFSCIPLDEKPLSEQLKELDTGNGEEQSVTSNSVPLDTGRKNAPRLSWSLGTGDQKASSTGTRVPHWDFTTIFLPNVASDQPCIHLPAPDSKLLPENVPGREVDAASWCRRINQKQERLTQKEREQWERESKYKSSISADREVRCCMNWQEYKALLRWRSQQRVWRQPLHPWDQAVTPLLQPEEATSLAAVRQQISVLQPSHILDGASWLQEDLESIKIDFNVYQADAVAKFKKTNPGKPYVRMCVQSFDEQIPSLRALKQVTCQSGDVPVVFALVDHGEIAFYSLKEFKLPVDVNY", "length": 512, "header": "tr|A0A8V1ALX5-1|A0A8V1AEY4_CHICK Computationally mapped isoform of tRNA splicing endonuclease subunit 54 OS=Gallus gallus OX=9031 GN=TSEN54 PE=1 SV=1 CANONICAL=A0A8V1AEY4-1" }, "locus": { "chromosome": "18", "start_pos": 11525020, "end_pos": 11517268, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071903.1", "url": "https://www.ensembl.org/id/ENSGALT00010071903.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044593.1", "url": "https://www.ensembl.org/id/ENSGALP00010044593.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:422126", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422126", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6AEJ0-1", "protein_name": "tRNA splicing endonuclease subunit 54", "gene_name": "Tsen54", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSRRGPQPRRGAFGGWGGDSAPVASELRAARSRSQKLPQRSHGPKDFLPDGSEAQAERLRLCRQELWQLLAEERVERLGSLVAAEWRPEEGFVELTSPAGKFWQTMGYSEEGRQRLHPEEALYLLECGSIQLFYQDLPLSIQEAYQLLLTEDTLSFLQYQVFSHLKRLGYVVRRFQLSSVVSPYERQLNLDGYAQCLEDGSGKRKRSSSCRSVNKKAKALQNSLPPVSLADSSPPACDQSSPYPEEKPRDSSPEQGSELPMQFLGSPEPCPDPGREDAGCDQESDKIENGAKGTPKPRWNFERISFPNMASDSRHTLLPAPAPELLPVNVIGRGTDAESWCQKLNQRREKLSRRDREQQAEVRQFREDVNADPEVQGCSTWQEYKELLRRRQMQRSQPRPPHLWGQSVTPLLNPDTADSPAAVLQRISVLQTTHLADGGYRLLEKSGGLEISFDVYQADAVATFRKNSPGKPYVRMCISGFDEPVPDLCSLKRLTYQSGDVPLIFALVDHGDISFYSFRDFTLPQDLGH", "length": 529 }, "evidence": [ { "id": "A0A8V1AEY4", "url": "https://omabrowser.org/oma/group/A0A8V1AEY4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7Z6J9-1", "protein_name": "tRNA-splicing endonuclease subunit Sen54", "gene_name": "TSEN54", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEPEPEPAAVEVPAGRVLSARELFAARSRSQKLPQRSHGPKDFLPDGSAAQAERLRRCREELWQLLAEQRVERLGSLVAAEWRPEEGFVELKSPAGKFWQTMGFSEQGRQRLHPEEALYLLECGSIHLFHQDLPLSIQEAYQLLLTDHTVTFLQYQVFSHLKRLGYVVRRFQPSSVLSPYERQLNLDASVQHLEDGDGKRKRSSSSPRSINKKAKALDNSLQPKSLAASSPPPCSQPSQCPEEKPQESSPMKGPGGPFQLLGSLGPSPGPAREGVGCSWESGRAENGVTGAGKRRWNFEQISFPNMASDSRHTLLRAPAPELLPANVAGRETDAESWCQKLNQRKEKLSRREREHHAEAAQFQEDVNADPEVQRCSSWREYKELLQRRQVQRSQRRAPHLWGQPVTPLLSPGQASSPAVVLQHISVLQTTHLPDGGARLLEKSGGLEIIFDVYQADAVATFRKNNPGKPYARMCISGFDEPVPDLCSLKRLSYQSGDVPLIFALVDHGDISFYSFRDFTLPQDVGH", "length": 526 }, "evidence": [ { "id": "A0A8V1AEY4", "url": "https://omabrowser.org/oma/group/A0A8V1AEY4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8C2A2-1", "protein_name": "tRNA-splicing endonuclease subunit Sen54", "gene_name": "Tsen54", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEPEPEPGSVEVPAGRVLSASELRAARSRSQKLPQRSHGPKDFLPDGSEAQAERLRLCRQELWQLLAEERVERLGSLVAAEWKPEEGFVELTSPAGKFWQTMGYSEEGRQRLHPEEALYLLECGSIQLFYQDLPLSIQEAYQLLLTEDTLSFLQYQVFSHLKRLGYVVRRFQLSSVVSPYERQLNLDGYAQCLEDGSGKRKRSSSCRSVNKKPKVLQNSLPPVSLAASSSPACDQSSQYPEEKSQDSSPRQGSELPLQFLGSSEPCSDLAREDVGCDRESHKIENGAKGTPKLRWNFEQISFPNMASDSRHTFLPAPAPELLPANVIGRGTDAESWCQKLNQRREKLSRRDREQQAVVQQFREDVNADPEVRGCSSWQEYKELLQRRQTQKSQPRPPHLWGQSVTPLLDPDKADCPAAVLQHISVLQTTHLADGGYRLLEKSGGLQISFDVYQADAVATFRKNSPGKPYVRMCISGFDDPVPDLCSLKCLTYQSGDVPLIFALVDHGDISFYSFRDFTLPRDLGH", "length": 525 }, "evidence": [ { "id": "A0A8V1AEY4", "url": "https://omabrowser.org/oma/group/A0A8V1AEY4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "tRNA-intron endonuclease complex", "id": "GO:0000214", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000214", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEY4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEY4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "tRNA-type intron splice site recognition and cleavage", "id": "GO:0000379", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000379", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEY4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEY4" } ], "pmid": "" }, { "name": "tRNA processing", "id": "GO:0008033", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008033", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEY4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEY4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AEY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEY4" }, { "id": "PF12928", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12928" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "tRNA-splicing endonuclease subunit Sen54 N-terminal", "eco_id": "ECO_0000259", "start_pos": 45, "end_pos": 111, "start_aa": "Arg", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AEZ6-1", "uniprot_ac": "A0A8V1AEZ6", "uniprot_id": "A0A8V1AEZ6_CHICK", "mass": { "chemical_mass": 37489.0, "monoisotopic_mass": 37489.0 }, "refseq": {}, "gene_names": [ { "name": "ZSWIM7", "type": "recommended", "evidence": [ { "id": "A0A8V1AEZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEZ6" } ] } ], "protein_names": [ { "name": "Zinc finger SWIM-type containing 7", "type": "synonym", "evidence": [ { "id": "A0A8V1AEZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEZ6/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEZ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEZ6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ZSWIM7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEZ6", "locus": { "chromosome": "19", "start_pos": 6934634, "end_pos": 6945215, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029727", "url": "https://www.ensembl.org/id/ENSGALG00010029727" } ] } } ], "crossref": [ { "id": "A0A8V1AEZ6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AEZ6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000023686", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000023686", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR007527", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007527", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A1L1RPB2", "url": "https://www.orthodb.org/?gene=A0A1L1RPB2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AEZ0", "url": "https://www.orthodb.org/?gene=A0A8V1AEZ0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AEZ6", "url": "https://www.orthodb.org/?gene=A0A8V1AEZ6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ALY3", "url": "https://www.orthodb.org/?gene=A0A8V1ALY3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ANJ2", "url": "https://www.orthodb.org/?gene=A0A8V1ANJ2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1APY8", "url": "https://www.orthodb.org/?gene=A0A8V1APY8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR28498", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28498", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR28498:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28498:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04434", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04434", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A1L1RPB2", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RPB2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1L1RPB2-1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RPB2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AEZ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEZ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AEZ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEZ0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AEZ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEZ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AEZ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEZ6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALY3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALY3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALY3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALY3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ANJ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANJ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ANJ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANJ2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1APY8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APY8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1APY8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APY8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLELNTQLESGPEAERSALHIPDSALFQPLQKENQQPPGLLTLSSCPCMKATFAIWKRQTALELRSGSGLPPLSAPARYQAVGVDDGPPVVGLVRQAQRLVQQPLGFTQFALHDAELRAERVRCGYGVGMVRYGVGEPFSPALPCGAPGPPGGRKLTPRGRHFRRAQRLTLAFFSRRIMASSPSSSSSSLGEREKAAGRSPEGSAREMDSTLPAVAEELLKEIRKAFQETSHVPDDLLLGLKFIFGPSAVPALDLVDQRSVTRVVSPSGRTAYQVLGSSGKLYTCYSSCHFCTCPAFGFTVLQKSESLLCKHILAVYLSQAMGACQELTVSEEQLTSILLAEEEDEG", "length": 347, "header": "tr|A0A8V1AEZ6-1|A0A8V1AEZ6_CHICK Isoform 1 of Zinc finger SWIM-type containing 7 OS=Gallus gallus OX=9031 GN=ZSWIM7 PE=4 SV=1 CANONICAL=A0A8V1AEZ6-1" }, "isoforms": [ { "isoform_ac": "A0A1L1RPB2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEZ6/entry#A0A1L1RPB2-1", "sequence": { "sequence": "HLTSCSRGASEGDQKGFSGDLPRLKFIFGPSAVPALDLVDQRSVTRVVSPSGRTAYQVLGSSGKLYTCYSSCHFCTCPAFGFTVLQKSESLLCKHILAVYLSQAMGACQELTVSEEQLTSILLAEEEDEG", "length": 130, "header": "tr|A0A1L1RPB2-1|A0A1L1RPB2_CHICK Computationally mapped isoform of Zinc finger SWIM-type containing 7 OS=Gallus gallus OX=9031 GN=ZSWIM7 PE=4 SV=1 CANONICAL=A0A8V1AEZ6-1" }, "locus": { "chromosome": "19", "start_pos": 6943575, "end_pos": 6934824, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071911.1", "url": "https://www.ensembl.org/id/ENSGALT00010071911.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044601.1", "url": "https://www.ensembl.org/id/ENSGALP00010044601.1" } ] } }, { "isoform_ac": "A0A8V1AEZ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEZ6/entry#A0A8V1AEZ0-1", "sequence": { "sequence": "SASWENKIRRKLEKSNQQLPDDLLLGLKFIFGPSAVPALDLVDQRSVTRVVSPSGRTAYQVLGSSGKLYTCYSSCHFCTCPAFGFTVLQKSESLLCKHILAVYLSQAMGACQELTVSEEQLTSILLAEEEDEG", "length": 133, "header": "tr|A0A8V1AEZ0-1|A0A8V1AEZ6_CHICK Computationally mapped isoform of Zinc finger SWIM-type containing 7 OS=Gallus gallus OX=9031 GN=ZSWIM7 PE=4 SV=1 CANONICAL=A0A8V1AEZ6-1" }, "locus": { "chromosome": "19", "start_pos": 6942547, "end_pos": 6934824, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071909.1", "url": "https://www.ensembl.org/id/ENSGALT00010071909.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044599.1", "url": "https://www.ensembl.org/id/ENSGALP00010044599.1" } ] } }, { "isoform_ac": "A0A8V1AEZ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEZ6/entry#A0A8V1AEZ6-1", "sequence": { "sequence": "MLELNTQLESGPEAERSALHIPDSALFQPLQKENQQPPGLLTLSSCPCMKATFAIWKRQTALELRSGSGLPPLSAPARYQAVGVDDGPPVVGLVRQAQRLVQQPLGFTQFALHDAELRAERVRCGYGVGMVRYGVGEPFSPALPCGAPGPPGGRKLTPRGRHFRRAQRLTLAFFSRRIMASSPSSSSSSLGEREKAAGRSPEGSAREMDSTLPAVAEELLKEIRKAFQETSHVPDDLLLGLKFIFGPSAVPALDLVDQRSVTRVVSPSGRTAYQVLGSSGKLYTCYSSCHFCTCPAFGFTVLQKSESLLCKHILAVYLSQAMGACQELTVSEEQLTSILLAEEEDEG", "length": 347, "header": "tr|A0A8V1AEZ6-1|A0A8V1AEZ6_CHICK Isoform 1 of Zinc finger SWIM-type containing 7 OS=Gallus gallus OX=9031 GN=ZSWIM7 PE=4 SV=1 CANONICAL=A0A8V1AEZ6-1" }, "locus": { "chromosome": "19", "start_pos": 6945016, "end_pos": 6934824, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071914.1", "url": "https://www.ensembl.org/id/ENSGALT00010071914.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044604.1", "url": "https://www.ensembl.org/id/ENSGALP00010044604.1" } ] } }, { "isoform_ac": "A0A8V1ALY3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEZ6/entry#A0A8V1ALY3-1", "sequence": { "sequence": "MDSTLPAVAEELLKEIRKAFQETSHVPDDLLLGDVELLGILDALLRISENMLKFIFGPSAVPALDLVDQRSVTRVVSPSGRTAYQVLGSSGKLYTCYSSCHFCTCPAFGFTVLQKSESLLCKHILAVYLSQAMGACQELTVSEEQLTSILLAEEEDEG", "length": 158, "header": "tr|A0A8V1ALY3-1|A0A8V1AEZ6_CHICK Computationally mapped isoform of Zinc finger SWIM-type containing 7 OS=Gallus gallus OX=9031 GN=ZSWIM7 PE=4 SV=1 CANONICAL=A0A8V1AEZ6-1" }, "locus": { "chromosome": "19", "start_pos": 6943583, "end_pos": 6934824, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071913.1", "url": "https://www.ensembl.org/id/ENSGALT00010071913.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044603.1", "url": "https://www.ensembl.org/id/ENSGALP00010044603.1" } ] } }, { "isoform_ac": "A0A8V1ANJ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEZ6/entry#A0A8V1ANJ2-1", "sequence": { "sequence": 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"table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AF02-1", "uniprot_ac": "A0A8V1AF02", "uniprot_id": "A0A8V1AF02_CHICK", "mass": { "chemical_mass": 44505.0, "monoisotopic_mass": 44505.0 }, "refseq": { "ac": "XP_040508418", "name": "hemojuvelin", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040508418" }, "gene_names": [ { "name": "LOC101751669", "type": "recommended", "evidence": [ { "id": "A0A8V1AF02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF02" } ] }, { "name": "LOC101751669", "type": "synonym", "evidence": [ { "id": "XP_040508418", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040508418" } ] } ], "protein_names": [ { "name": "Hemojuvelin BMP co-receptor", "type": "synonym", "evidence": [ { "id": "A0A8V1AF02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF02/entry#names_and_taxonomy" } ] }, { 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This record is derived from a genomic sequence (NC_052556.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040508418", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040508418" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AF02", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF02" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC101751669", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF02", "locus": {} } ], "crossref": [ { "id": "A0A8V1AF02", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AF02", "database": "AlphaFoldDB", "categories": [] }, { "id": "101751669", "url": "https://www.ncbi.nlm.nih.gov/gene/101751669", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR009496", "url": 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"categories": [ "Protein Classification" ] }, { "id": "PF06534", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06534", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF06535", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06535", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040508418", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040508418", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AF02", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF02", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AF02-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF02-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGKASCSKSPAQLEHGLFLQALLLLLLLCCRHVSSQCKILRCNSDFVAATLNLRGAARASAYCTALRSYSHCTRRTARTCRGDLAFHSAVHGIEDLMIQHNCSKDGPTSPPRPRPPAPDHQSFPASEMCDYEKTFRSKHGRPPRYRHCAAFGDPHVRTFHDDFHTCRVEGAWPLLDNEYLFVQATSAPVAEGSNATVTSKLTIIFKHMKECTEQKVYRAELDNVPAAFEDGSVTGGDRPGGGALHIRERSPGRHVEIRAPYIGTTIAVRQAARQLSFSIRAAEEVTRAFTAEQDLQLCVAGCPRGQRISRSVRSRAAAQAARALCKATLPVEDVYFQSCVFDVATSGDANFTMAARGALEDARDFLPDVEKLHIFQAGQGCPRAPPSFPVLLLLLLCGLCALWLQL", "length": 406, "header": "tr|A0A8V1AF02-1|A0A8V1AF02_CHICK Isoform 1 of Hemojuvelin BMP co-receptor OS=Gallus gallus OX=9031 GN=LOC101751669 PE=3 SV=1 CANONICAL=A0A8V1AF02-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AF02-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF02/entry#A0A8V1AF02-1", "sequence": { "sequence": "MGKASCSKSPAQLEHGLFLQALLLLLLLCCRHVSSQCKILRCNSDFVAATLNLRGAARASAYCTALRSYSHCTRRTARTCRGDLAFHSAVHGIEDLMIQHNCSKDGPTSPPRPRPPAPDHQSFPASEMCDYEKTFRSKHGRPPRYRHCAAFGDPHVRTFHDDFHTCRVEGAWPLLDNEYLFVQATSAPVAEGSNATVTSKLTIIFKHMKECTEQKVYRAELDNVPAAFEDGSVTGGDRPGGGALHIRERSPGRHVEIRAPYIGTTIAVRQAARQLSFSIRAAEEVTRAFTAEQDLQLCVAGCPRGQRISRSVRSRAAAQAARALCKATLPVEDVYFQSCVFDVATSGDANFTMAARGALEDARDFLPDVEKLHIFQAGQGCPRAPPSFPVLLLLLLCGLCALWLQL", "length": 406, "header": "tr|A0A8V1AF02-1|A0A8V1AF02_CHICK Isoform 1 of Hemojuvelin BMP co-receptor OS=Gallus gallus OX=9031 GN=LOC101751669 PE=3 SV=1 CANONICAL=A0A8V1AF02-1" }, "locus": { "chromosome": "25", "start_pos": 760985, "end_pos": 754685, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066818.1", "url": "https://www.ensembl.org/id/ENSGALT00010066818.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040890.1", "url": "https://www.ensembl.org/id/ENSGALP00010040890.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 108, "start_aa": "Thr", "end_pos": 108, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr108", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A287AYZ9-1", "protein_name": "Hemojuvelin", "gene_name": "HJV", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGDPGQFPSPWSPHGSPPTLSILTLLLLLCGHAHSQCKILRCNAEYVSSTLSLRSGGSPGALRGGGSGGGGRGGGLGSSGLCRALRSYALCTRRTARTCRGDLAFHSAVHGIEDLMIQHNCSRQGPTAPPPPRGPALPGAGPARSSGAPAPDPCDYEGRFSQLHGQPPGFLHCASFGDPHVRSFHHHFHTCRVQGAWPLLDNDFLFVQATSFPVALGANATTTQKLTIIFKNMQECIDQKVYRAEVDNLPAAFEDGSINGGDRPGGSSLSIRTANPGSHVEIQAAYIGTTIIIRQTARQLSFSIKVAEDVARAFSAEQDLQLCVGGCPPSQRLSRSERSRRGAITIDTARRLCKEGLPVEDVYFHSCVFDVFTSGDPNFTVAAQAALEDARAFLPDLEKLHLFPSDAGVPLSSASLPAPLLSGLFVLWLCSQ", "length": 432 }, "evidence": [ { "id": "A0A8V1AF02", "url": "https://omabrowser.org/oma/group/A0A8V1AF02/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "E1BI30-1", "protein_name": "Hemojuvelin", "gene_name": "HJV", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGDPGQSPSPWSPHGSPPTLSILTLLLLLCGHAYSQCKILRCNAEYVSSTLSLRGGGSPGSLRGGGRGGGVGSSGLCRALRSYALCTRRTARTCRGDLAFHSAVHGIEDLMIQHNCSRQGPTAPPPPRGPVFPGAGPIRASGSPAPDPCDYEGRFSRLHRQPPGFLHCASFGDPHVRTFHHHFHTCRVQGAWPLLDNDFLFVQATSSPVALGANATTTRKLTIIFKNMQECIDQKVYQAEVDNLPAAFEDGSINGGDRPGGSSLSIRTANPGSHVEIRAAYIGTTIIIRQTAGQLSFSIRVAEDVARAFSAEQDLQLCVGGCPPSQRLSRSVRSRRGTITMDTARQLCKEGLPVEDAYFHSCVFDVLISGDPNFTVAAQAALEDARAFLPDLEKLHLFPSDAGVPLSSATLPPPLLSGLFVLWLCIQ", "length": 427 }, "evidence": [ { "id": "A0A8V1AF02", "url": "https://omabrowser.org/oma/group/A0A8V1AF02/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q6ZVN8-1", "protein_name": "Hemojuvelin", "gene_name": "HJV", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGEPGQSPSPRSSHGSPPTLSTLTLLLLLCGHAHSQCKILRCNAEYVSSTLSLRGGGSSGALRGGGGGGRGGGVGSGGLCRALRSYALCTRRTARTCRGDLAFHSAVHGIEDLMIQHNCSRQGPTAPPPPRGPALPGAGSGLPAPDPCDYEGRFSRLHGRPPGFLHCASFGDPHVRSFHHHFHTCRVQGAWPLLDNDFLFVQATSSPMALGANATATRKLTIIFKNMQECIDQKVYQAEVDNLPVAFEDGSINGGDRPGGSSLSIQTANPGNHVEIQAAYIGTTIIIRQTAGQLSFSIKVAEDVAMAFSAEQDLQLCVGGCPPSQRLSRSERNRRGAITIDTARRLCKEGLPVEDAYFHSCVFDVLISGDPNFTVAAQAALEDARAFLPDLEKLHLFPSDAGVPLSSATLLAPLLSGLFVLWLCIQ", "length": 426 }, "evidence": [ { "id": "A0A8V1AF02", "url": "https://omabrowser.org/oma/group/A0A8V1AF02/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q7TQ32-1", "protein_name": "Hemojuvelin", "gene_name": "Hjv", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGQSPSPRSPHGSPPTLSTLTLLLLLCGQAHSQCKILRCNAEYVSSTLSLRGGGSPDTPRGGGRGGLASGGLCRALRSYALCTRRTARTCRGDLAFHSAVHGIEDLMIQHNCSRQGPTAPPPARGPALPGAGPAPLTPDPCDYEARFSRLHGRAPGFLHCASFGDPHVRSFHNQFHTCRVQGAWPLLDNDFLFVQATSSPVSSGANATTIRKITIIFKNMQECIDQKVYQAEVDNLPAAFEDGSINGGDRPGGSSLSIQTANLGSHVEIRAAYIGTTIIIRQTAGQLSFSIRVAEDVARAFSAEQDLQLCVGGCPPSQRLSRSERNRRGAIAIDTARRLCKEGLPVEDAYFQSCVFDVSVSGDPNFTVAAQTALDDARIFLTDLENLHLFPSDAGPPLSPAICLVPLLSALFVLWLCFSK", "length": 420 }, "evidence": [ { "id": "A0A8V1AF02", "url": "https://omabrowser.org/oma/group/A0A8V1AF02/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8N7M5-1", "protein_name": "Hemojuvelin", "gene_name": "Hjv", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGDRGRSPSLRSPHGSPPTLSTLTLLLLLCGQAHSQCKILRCNAEYVSFTLSLRGGGSPDTPRGGGRGGPASGGLCRALRSYALCTRRTARTCRGDLAFHSAVHGIEDLMIQHNCSRQGPTASPPARGPALPGAGPAPLTPDPCDYEARFSRLHGRTPGFLHCASFGDPHVRSFHNHFHTCRVQGAWPLLDNDFLFVQATSSPVASGANATTIRKITIIFKNMQECIDQKVYQAEVDNLPAAFEDGSVNGGDRPGGSSLSIQTANLGSHVEIRAAYIGTTIIVRQTAGQLSFSIRVAEDVARAFSAEQDLQLCVGGCPPSQRLSRSERNRRGAIAIDTARRLCKEGLPVEDAYFQSCVFDVSVSGDPNFTVAAQSALDDARVFLTDLENLHLFPVDAGPPLSPATCLVRLLSVLFVLWFCIQ", "length": 422 }, "evidence": [ { "id": "A0A8V1AF02", "url": "https://omabrowser.org/oma/group/A0A8V1AF02/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AF02", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF02" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AF02", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF02" } ], "pmid": "" }, { "name": "intracellular iron ion homeostasis", "id": "GO:0006879", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006879", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AF02", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF02" } ], "pmid": "" }, { "name": "BMP signaling pathway", "id": "GO:0030509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030509", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AF02", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF02" } ], "pmid": "" }, { "name": "activin receptor signaling pathway", "id": "GO:0032924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032924", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AF02", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF02" } ], "pmid": "" }, { "name": "protein autoprocessing", "id": "GO:0016540", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016540", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AF02", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF02" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AF02", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF02" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AF02", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF02" } ], "pmid": "" }, { "name": "cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AF02", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF02" } ], "pmid": "" }, { "name": "HFE-transferrin receptor complex", "id": "GO:1990712", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990712", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AF02", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF02" } ], "pmid": "" }, { "name": "BMP receptor complex", "id": "GO:0070724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070724", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AF02", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF02" } ], "pmid": "" }, { "name": "side of membrane", "id": "GO:0098552", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098552", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AF02", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF02" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "coreceptor activity", "id": "GO:0015026", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015026", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AF02", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF02" } ], "pmid": "" }, { "name": "BMP receptor activity", "id": "GO:0098821", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098821", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AF02", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF02" } ], "pmid": "" }, { "name": "BMP binding", "id": "GO:0036122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036122", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AF02", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF02" } ], "pmid": "" }, { "name": "transferrin receptor binding", "id": "GO:1990459", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990459", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AF02", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF02" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 101, "end_pos": 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"http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13843", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13843:SF11", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13843:SF11", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF23415", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23415", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25281", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25281", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1AF10", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF10", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AF10-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF10-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AH19", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH19", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AH19-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH19-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAAVAAAPPGPAAGPRRFSLLAIVGGGCHRPGLLAAALQQLERGIRSWDIDLTSCNLDEQLKLFVSRHSATFSSIVKGQRTLHHRGDVLETLVLLNPSDKSLCDELRNLITDVSQHKLLVFAGPCVEETGELMLQTGCFSLRDFIQIFTDKEVGEILSSADPSAKARLTISCPDFGEWKDSGLDHHNLQDFIELRYNPGCILPEMEGLEEFMEYLSESLEPQSPFDLLEPPTMVGFLKLSKPCCYIFPGGRGDSAFFAVNGFNVLVNGGSNPKSSFWKLVRHLDRIDSILVTHAGTDSLPGINSLLQRKLAELEEEPASQGSQGNGDWARNLISPELGVVFLNASEKLKAIEGNSRVLKSCDEAALTLHYLEKLGIRPNPLARDSSPRVEPTVLFQKMGVGRLDMYVLNPVRGTKELEFLLQHWSGNGYPEEQELPLQCLTSVCALLVWHPVSPAEKIIRVLFPGCTPQARILEGLEKVKHLEFLKQPVVTKNDLKGPQADKQLKQRRTESKESLASASKLSLVDAGVAKEKALKTVERKEVKVGTKEKPKALGEVARAGSEEEKAKPAKPDSSAEKLKAEAKPKVSKEKAVPKKEPVPRKEEKKPLKKEESTEGKLEPKKEAKAVKKDVKAETLRKDTKDSKAEPKAAAKPPARKTPAPDARKPLAKAGSIKRATLKKEPEKPKAKGGKEPGGKKEPGPTEGSKPSSPEDMVLDAEGRRRKEESPDEGITTAESELEPSPLENGGAGRGSEPSCVENGVEEPESPQRFRYPEGSPWRAVGPPSPLAKTPRSERSVNFDLTPTGLLPPGPEGSEDPCGSSEEKTLEMMSPGSSGPASAGHTPFHQSPVEDGGEDSGANAQPNPWAPNRAPQDGNEKQAGCLSLSPFKDDVPDVSPTVTTPSLPAEVGSPHSTEVDESLSVSFEQVLPPVSESPQEESMRPRATPEPDPAKGGGLSLPLRPCHHPHPPPAPRHGRRSDSPHDVDLCLVSPCEFEHPKAGRSPAVSPRDLSDSDPSQELQPPAPHRGRAPPQPVGETPPTSVSESLPTLSDSDVPPATEDCPSLLADGLESDEDSEQPHRGPPRARDPLPAPMKDPCPLPAQPGICMVDPEALPKKEPPLGKAKRTPSRVGAVPATPKPDAPKATSLAPKGRGPTGDKARLPPGDKKGPPGGTGTMRSAGFRAPLGAGRASPAGSRAAAPQGPPVYVDLAYLPGSWSARTVDEEFFRRVRSLCYVVSGDDHLKEGVLRPILDALLAGKHQWGTDTQVTLIPTFDSLVMHEWYQETHERQQELGITVLGSNSTVAMQDETFPACKVEF", "length": 1316, "header": "tr|A0A8V1AF10-1|A0A8V1AF10_CHICK Isoform 1 of Microtubule associated protein 1S OS=Gallus gallus OX=9031 GN=MAP1S PE=1 SV=1 CANONICAL=A0A8V1AF10-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AF10-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF10/entry#A0A8V1AF10-1", "sequence": { "sequence": "MAAAVAAAPPGPAAGPRRFSLLAIVGGGCHRPGLLAAALQQLERGIRSWDIDLTSCNLDEQLKLFVSRHSATFSSIVKGQRTLHHRGDVLETLVLLNPSDKSLCDELRNLITDVSQHKLLVFAGPCVEETGELMLQTGCFSLRDFIQIFTDKEVGEILSSADPSAKARLTISCPDFGEWKDSGLDHHNLQDFIELRYNPGCILPEMEGLEEFMEYLSESLEPQSPFDLLEPPTMVGFLKLSKPCCYIFPGGRGDSAFFAVNGFNVLVNGGSNPKSSFWKLVRHLDRIDSILVTHAGTDSLPGINSLLQRKLAELEEEPASQGSQGNGDWARNLISPELGVVFLNASEKLKAIEGNSRVLKSCDEAALTLHYLEKLGIRPNPLARDSSPRVEPTVLFQKMGVGRLDMYVLNPVRGTKELEFLLQHWSGNGYPEEQELPLQCLTSVCALLVWHPVSPAEKIIRVLFPGCTPQARILEGLEKVKHLEFLKQPVVTKNDLKGPQADKQLKQRRTESKESLASASKLSLVDAGVAKEKALKTVERKEVKVGTKEKPKALGEVARAGSEEEKAKPAKPDSSAEKLKAEAKPKVSKEKAVPKKEPVPRKEEKKPLKKEESTEGKLEPKKEAKAVKKDVKAETLRKDTKDSKAEPKAAAKPPARKTPAPDARKPLAKAGSIKRATLKKEPEKPKAKGGKEPGGKKEPGPTEGSKPSSPEDMVLDAEGRRRKEESPDEGITTAESELEPSPLENGGAGRGSEPSCVENGVEEPESPQRFRYPEGSPWRAVGPPSPLAKTPRSERSVNFDLTPTGLLPPGPEGSEDPCGSSEEKTLEMMSPGSSGPASAGHTPFHQSPVEDGGEDSGANAQPNPWAPNRAPQDGNEKQAGCLSLSPFKDDVPDVSPTVTTPSLPAEVGSPHSTEVDESLSVSFEQVLPPVSESPQEESMRPRATPEPDPAKGGGLSLPLRPCHHPHPPPAPRHGRRSDSPHDVDLCLVSPCEFEHPKAGRSPAVSPRDLSDSDPSQELQPPAPHRGRAPPQPVGETPPTSVSESLPTLSDSDVPPATEDCPSLLADGLESDEDSEQPHRGPPRARDPLPAPMKDPCPLPAQPGICMVDPEALPKKEPPLGKAKRTPSRVGAVPATPKPDAPKATSLAPKGRGPTGDKARLPPGDKKGPPGGTGTMRSAGFRAPLGAGRASPAGSRAAAPQGPPVYVDLAYLPGSWSARTVDEEFFRRVRSLCYVVSGDDHLKEGVLRPILDALLAGKHQWGTDTQVTLIPTFDSLVMHEWYQETHERQQELGITVLGSNSTVAMQDETFPACKVEF", "length": 1316, "header": "tr|A0A8V1AF10-1|A0A8V1AF10_CHICK Isoform 1 of Microtubule associated protein 1S OS=Gallus gallus OX=9031 GN=MAP1S PE=1 SV=1 CANONICAL=A0A8V1AF10-1" }, "locus": { "chromosome": "28", "start_pos": 3756288, "end_pos": 3749681, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066841.1", "url": "https://www.ensembl.org/id/ENSGALT00010066841.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040900.1", "url": "https://www.ensembl.org/id/ENSGALP00010040900.1" } ] } }, { "isoform_ac": "A0A8V1AH19-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF10/entry#A0A8V1AH19-1", "sequence": { "sequence": "MAAAVAAAPPGPAAGPRRFSLLAIVGGGCHRPGLLAAALQQLERGIRSWDIDLTSCNLDEQLKLFVSRHSATFSSIVKGQRTLHHRGDVLETLVLLNPSDKSLCDELRNLITDVSQHKLLVFAGPCVEETGELMLQTGCFSLRDFIQIFTDKEVGEILSSADPSAKARLTISCPDFGEWKDSGLDHHNLQDFIELRYNPGCILPEMEGLEEFMEYLSESLEPQSPFDLLEPPTMVGFLKLSKPCCYIFPGGRGDSAFFAVNGFNVLVNGGSNPKSSFWKLVRHLDRIDSILVTHAGTDSLPGINSLLQRKLAELEEEPASQGSQGNGDWARNLISPELGVVFLNASEKLKAIEGNSRVLKSCDEAALTLHYLEKLGIRPNPLARDSSPRVEPTVLFQKMGVGRLDMYVLNPVRGTKELEFLLQHWSGNGYPEEQELPLQCLTSVCALLVWHPVSPAEKIIRVLFPGCTPQARILEGLEKVKHLEFLKQPVVTKNDLKGPQADKQLKQRRTESKESLASASKLSLVDAGVAKEKALKTVERKEVKVGTKEKPKVSKEKAVPKKEPVPRKEEKKPLKKEESTEGKLEPKKEAKAVKKDVKAETLRKDTKDSKAEPKAAAKPPARKTPAPDARKPLAKAGSIKRATLKKEPEKPKAKGGKEPGGKKEPGPTEGSKPSSPEDMVLDAEGRRRKEESPDEGITTAESELEPSPLENGGAGRGSEPSCVENGVEEPESPQRFRYPEGSPWRAVGPPSPLAKTPRSERSVNFDLTPTGLLPPGPEGSEDPCGSSEEKTLEMMSPGSSGPASAGHTPFHQSPVEDGGEDSGANAQPNPWAPNRAPQDGNEKQAGCLSLSPFKDDVPDVSPTVTTPSLPAEVGSPHSTEVDESLSVSFEQVLPPVSESPQEESMRPRATPEPDPAKGGGLSLPLRPCHHPHPPPAPRHGRRSDSPHDVDLCLVSPCEFEHPKAGRSPAVSPRDLSDSDPSQELQPPAPHRGRAPPQPVGETPPTSVSESLPTLSDSDVPPATEDCPSLLADGLESDEDSEQPHRGPPRARDPLPAPMKDPCPLPAQPGICMVDPEALPKKEPPLGKAKRTPSRVGAVPATPKPDAPKATSLAPKGRGPTGDKARLPPGDKKGPPGGTGTMRSAGFRAPLGAGRASPAGSRAAAPQGPPVYVDLAYLPGSWSARTVDEEFFRRVRSLCYVVSGDDHLKEGVLRPILDALLAGKHQWGTDTQVTLIPTFDSLVMHEWYQETHERQQELGITVLGSNSTVAMQDETFPACKVEF", "length": 1282, "header": "tr|A0A8V1AH19-1|A0A8V1AF10_CHICK Computationally mapped isoform of Microtubule associated protein 1S OS=Gallus gallus OX=9031 GN=MAP1S PE=1 SV=1 CANONICAL=A0A8V1AF10-1" }, "locus": { "chromosome": "28", "start_pos": 3756288, "end_pos": 3749681, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066844.1", "url": "https://www.ensembl.org/id/ENSGALT00010066844.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040903.1", "url": "https://www.ensembl.org/id/ENSGALP00010040903.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1036, "start_aa": "Thr", "end_pos": 1036, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1036", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1154, "start_aa": "Thr", "end_pos": 1154, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1154", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 702, "start_aa": "Thr", "end_pos": 702, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr702", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 897, "start_aa": "Thr", "end_pos": 897, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr897", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 9, "go_terms": [ { "name": "metaphase chromosome alignment", "id": "GO:0051310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051310", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AF10", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF10" } ], "pmid": "" }, { "name": "axonogenesis", "id": "GO:0007409", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007409", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AF10", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF10" } ], "pmid": "" }, { "name": "dendrite development", "id": "GO:0016358", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016358", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AF10", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF10" } ], "pmid": "" }, { "name": "microtubule cytoskeleton organization", "id": "GO:0000226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000226", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AF10", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF10" } ], "pmid": "" }, { "name": "mitotic spindle organization", "id": "GO:0007052", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007052", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AF10", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF10" } ], "pmid": "" }, { "name": "microtubule anchoring at centrosome", "id": "GO:0034454", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034454", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AF10", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF10" } ], "pmid": "" }, { "name": "microtubule bundle formation", "id": "GO:0001578", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001578", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AF10", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF10" } ], "pmid": "" }, { "name": "regulation of microtubule depolymerization", "id": "GO:0031114", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031114", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AF10", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF10" } ], "pmid": "" }, { "name": "nervous system development", 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"actin filament binding", "id": "GO:0051015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051015", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AF10", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF10" } ], "pmid": "" }, { "name": "beta-tubulin binding", "id": "GO:0048487", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048487", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AF10", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF10" } ], "pmid": "" }, { "name": "WD40-repeat domain binding", "id": "GO:0071987", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071987", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AF10", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF10" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 11, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AF10", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF10" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AF10", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF10" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AF10", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF10" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AF10", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF10" } ], "pmid": "" }, { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AF10", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF10" } ], "pmid": "" }, { "name": "dendrite", "id": "GO:0030425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AF10", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF10" } ], "pmid": "" }, { "name": "neuronal cell body", "id": "GO:0043025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043025", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AF10", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF10" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AF10", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF10" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AF10", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF10" } ], "pmid": "" }, { "name": "microtubule associated complex", "id": "GO:0005875", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005875", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AF10", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF10" } ], "pmid": "" }, { "name": "mitotic spindle microtubule", "id": "GO:1990498", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990498", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AF10", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF10" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1299, "end_pos": 1301, "annotation": "n_glycosylation_sequon" }, { "start_pos": 344, "end_pos": 346, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AF10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF10" }, { "id": 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"database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PVV5-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PVV5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AF14", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF14", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AF14-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF14-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHF5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHF5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHF5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHF5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGDWSLPIGSLGEEVVAQLCELLDTASRGWRKLAEVAGAEKRFKCSEEELEMCSLKVLEPLGSPTQCLLQLLAERECTLRYLQGCLHRMGHTQACQVLSSAVHDVIRITVQPESQVVAEGTRVSLTCWASGPPGLTYQWFCGRQEVPGATAPELMVDTAAPLGLPQWYICRVSCGAAFAFSRWARIQVERSHSPESASGYCPSMAGLQILQQPRPCRLAEGDPLVLECRALGNPPPQYQWFRNRRPVEGARAPQLQVLQTPCLALHGTARHGVGQQSTAWGSRARRGAAEHGVGQQSTAWGSVVAPALHPPQVQLVTTAERGTYSCRVFNLFHELWSQEVDVEIGPRLFASGAPWQDGDGDSPEPGSPDQLYATDKVALLVGNMHYVHHKHLRAPMVDVHALSALLRQLDFKVVSLLDLRRDEMQMAVDEFLLLLDKGVYGLLYYAGHGYENFGTSFMVPIDAPGSYTSAHCLCVQHVLQRMQQRRTGLNIFLLDMCRKRNLNDDVIPQVGALEVTANIVFGYATCADAEAYELSQQGELSNGVFVTFLKRWLLEDEKITVLLDKVAEDMGTLELTRGRQALELRSNLSERRALTDPIRSLGQAETSARNLQWAKAHVLPESRHLRFDCGVTVQLGFAAEFSNIMIIYTRILAAPGDVTECVAKLTDLPEELDVDLKCTNRESPEELGSPLVPTWSVTCPSCCLYSRLCGLQRLRQELTFTVCLQYRYRHVADFVEERRAVSVGRPLIAKLNLSPPDPGKLPASGGSGSPLSASPPSSWGNSPEENLSPEVPGSHGV", "length": 797, "header": "tr|A0A8V1AF14-1|A0A8V1AF14_CHICK Isoform 1 of Paracaspase 2 OS=Gallus gallus OX=9031 GN=PCASP2 PE=4 SV=1 CANONICAL=A0A8V1AF14-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PVV5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF14/entry#A0A1D5PVV5-1", "sequence": { "sequence": "MGDWSLPIGSLGEEVVAQLCELLDTASRGWRKLAEVAGAEKRFKCSEEELEMCSLKVLEPLGSPTQCLLQLLAERECTLRYLQGCLHRMGHTQACQVLSSAVHDVIRITVQPESQVVAEGTRVSLTCWASGPPGLTYQWFCGRQEVPGATAPELMVDTAAPLGLPQWYICRVSCGAAFAFSRWARIQVERSHSPESASGYCPSMAGLQILQQPRPCRLAEGDPLVLECRALGNPPPQYQWFRNRRPVEGARAPQLQVQLVTTAERGTYSCRVFNLFHELWSQEVDVEIGPRLFASGAPWQDGDGDSPEPGSPDQLYATDKVALLVGNMHYVHHKHLRAPMVDVHALSALLRQLDFKVVSLLDLRRDEMQMAVDEFLLLLDKGVYGLLYYAGHGYENFGTSFMVPIDAPGSYTSAHCLCVQHVLQRMQQRRTGLNIFLLDMCRKRNLNDDVIPQVGALEVTANIVFGYATCADAEAYELSQQGELSNGVFVTFLKRWLLEDEKITVLLDKVAEDMGTLELTRGRQALELRSNLSERRALTDPIRSLGQAETSARNLQWAKAHVLPESRHLRFDCGVTVQLGFAAEFSNIMIIYTRILAAPGDVTECVAKLTDLPEELDVDLKCTNRESPEELGSPLVPTWSVTCPSCCLYSRLCGLQRLRQELTFTVCLQYRYRHVADFVEERRAVSVGRPLIAKLNLSPPDPGKLPASGGSGSPLSASPPSSWGNSPEENLSPEVPGSHGV", "length": 741, "header": "tr|A0A1D5PVV5-1|A0A1D5PVV5_CHICK Computationally mapped isoform of Paracaspase 2 OS=Gallus gallus OX=9031 GN=PCASP2 PE=4 SV=1 CANONICAL=A0A8V1AF14-1" }, "locus": { "chromosome": "28", "start_pos": 1397796, "end_pos": 1392974, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068087.1", "url": "https://www.ensembl.org/id/ENSGALT00010068087.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041830.1", "url": "https://www.ensembl.org/id/ENSGALP00010041830.1" } ] } }, { "isoform_ac": "A0A8V1AF14-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF14/entry#A0A8V1AF14-1", "sequence": { "sequence": "MGDWSLPIGSLGEEVVAQLCELLDTASRGWRKLAEVAGAEKRFKCSEEELEMCSLKVLEPLGSPTQCLLQLLAERECTLRYLQGCLHRMGHTQACQVLSSAVHDVIRITVQPESQVVAEGTRVSLTCWASGPPGLTYQWFCGRQEVPGATAPELMVDTAAPLGLPQWYICRVSCGAAFAFSRWARIQVERSHSPESASGYCPSMAGLQILQQPRPCRLAEGDPLVLECRALGNPPPQYQWFRNRRPVEGARAPQLQVLQTPCLALHGTARHGVGQQSTAWGSRARRGAAEHGVGQQSTAWGSVVAPALHPPQVQLVTTAERGTYSCRVFNLFHELWSQEVDVEIGPRLFASGAPWQDGDGDSPEPGSPDQLYATDKVALLVGNMHYVHHKHLRAPMVDVHALSALLRQLDFKVVSLLDLRRDEMQMAVDEFLLLLDKGVYGLLYYAGHGYENFGTSFMVPIDAPGSYTSAHCLCVQHVLQRMQQRRTGLNIFLLDMCRKRNLNDDVIPQVGALEVTANIVFGYATCADAEAYELSQQGELSNGVFVTFLKRWLLEDEKITVLLDKVAEDMGTLELTRGRQALELRSNLSERRALTDPIRSLGQAETSARNLQWAKAHVLPESRHLRFDCGVTVQLGFAAEFSNIMIIYTRILAAPGDVTECVAKLTDLPEELDVDLKCTNRESPEELGSPLVPTWSVTCPSCCLYSRLCGLQRLRQELTFTVCLQYRYRHVADFVEERRAVSVGRPLIAKLNLSPPDPGKLPASGGSGSPLSASPPSSWGNSPEENLSPEVPGSHGV", "length": 797, "header": "tr|A0A8V1AF14-1|A0A8V1AF14_CHICK Isoform 1 of Paracaspase 2 OS=Gallus gallus OX=9031 GN=PCASP2 PE=4 SV=1 CANONICAL=A0A8V1AF14-1" }, "locus": { "chromosome": "28", "start_pos": 1397796, "end_pos": 1392974, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068085.1", "url": "https://www.ensembl.org/id/ENSGALT00010068085.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041828.1", "url": "https://www.ensembl.org/id/ENSGALP00010041828.1" } ] } }, { "isoform_ac": "A0A8V1AHF5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF14/entry#A0A8V1AHF5-1", "sequence": { "sequence": "MGDWSLPIGSLGEEVVAQLCELLDTASRGWRKLAEVAGAEKRFKCSEEELEMCSLKVLEPLGSPTQCLLQLLAERECTLRYLQGCLHRMGHTQACQVLSSAVHDVIRITVQPESQVVAEGTRVSLTCWASGPPGLTYQWFCGRQEVPGATAPELMVDTAAPLGLPQWYICRVSCGAAFAFSRWARIQVERSHSPESASGYCPSMAGLQILQQPRPCRLAEGDPLVLECRALGNPPPQYQWFRNRRPVEGARAPQLQVQLVTTAERGTYSCRVFNLFHELWSQEVDVEIGPRLFASGAPWQDGDGDSPEPGSPDQLYATDKVALLVGNMHYVHHKHLRAPMVDVHALSALLRQLDFKVVSLLDLRRDEMQMAVDEFLLLLDKGVYGLLYYAGHGYENFGTSFMVPIDAPGSYTSAHCLCVQHVLQRMQQRRTGLNIFLLDMCRKRNLNDDVIPQVGALEVTANIVFGYATCADAEAYELSQQGELSNGVFVTFLKRWLLEDEKITVLLDKVAEDMGTLELTRGRQALELRSNLSERRALTDPIRSLGQAETSARNLQWAKAHVLPESRHLRFDCGVTVQLGFAAEFSNIMIIYTRILAAPGDVTECVAKLTDLPEELDVDLKCTNRESPEELGSPLVPTWSVTCPSCCLYSRLCGLQRLRQELTFTVCLQYRYRHVADFVEERRATSSSSRGTGTRSRVPTGSARSPDGVIGRPQCHRSRGCSSAPCLAPTDPICPNTFHVWNPEAPTCAIAPAPPQQCQPHTIPSAMAGHPTTRPPIPAPIGTPLPPLGLSPP", "length": 793, "header": "tr|A0A8V1AHF5-1|A0A8V1AF14_CHICK Computationally mapped isoform of Paracaspase 2 OS=Gallus gallus OX=9031 GN=PCASP2 PE=4 SV=1 CANONICAL=A0A8V1AF14-1" }, "locus": { "chromosome": "28", "start_pos": 1397796, "end_pos": 1391565, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068084.1", "url": "https://www.ensembl.org/id/ENSGALT00010068084.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041827.1", "url": "https://www.ensembl.org/id/ENSGALP00010041827.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AF14", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF14" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "cysteine-type endopeptidase activity", "id": "GO:0004197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004197", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AF14", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF14" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 587, "end_pos": 589, "annotation": "n_glycosylation_sequon" }, { "start_pos": 752, "end_pos": 754, "annotation": "n_glycosylation_sequon" }, { "start_pos": 786, "end_pos": 788, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AF14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF14" }, { "id": "PS50208", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50208" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Caspase family p20", "eco_id": "ECO_0000259", "start_pos": 374, "end_pos": 501, "start_aa": "Thr", "end_aa": "Asn", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1AF14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF14" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 106, "end_pos": 173, "start_aa": "Ile", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 587, "end_pos": 589 }, { "start_pos": 752, "end_pos": 754 }, { "start_pos": 786, "end_pos": 788 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AF36-1", "uniprot_ac": "A0A8V1AF36", "uniprot_id": "A0A8V1AF36_CHICK", "mass": { "chemical_mass": 19625.0, "monoisotopic_mass": 19625.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "DNA repair protein SWI5 homolog", "type": "recommended", "evidence": [ { "id": "A0A8V1AF36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF36/entry#names_and_taxonomy" } ] }, { "name": "Protein SAE3 homolog", "type": "synonym", "evidence": [ { "id": "A0A8V1AF36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF36/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Component of the SWI5-SFR1 complex, a complex required for double-strand break repair via homologous recombination.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AF36", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF36#function" }, { "database": "UniProtKB", "id": "ARBA00059338", "url": "https://www.uniprot.org/uniprotkb/ARBA00059338#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AF36", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF36" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF36", "locus": {} } ], "crossref": [ { "id": "A0A8V1AF36", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AF36", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR010760", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010760", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR28529", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28529", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR28529:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28529:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07061", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07061", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1AF36", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF36", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AF36-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF36-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "LGVPCAFPRRNAFPGAEGTAGPGTTTPSVPRAAGIQLPACPAPCPCGRCAREAAALAEQRCSPSGRIAPPAQRRALGGARRSGGAAFRSPVGRPPAPLAAPPPLRAGGEAPCDDVEALKEKDRALDREIAQLLSEGYSVEELEKHISLLHEYNEIKDAGQMLLGKLAVIRGVTTKQLYPEYDLELND", "length": 187, "header": "tr|A0A8V1AF36-1|A0A8V1AF36_CHICK Isoform 1 of DNA repair protein SWI5 homolog OS=Gallus gallus OX=9031 GN= PE=3 SV=1 CANONICAL=A0A8V1AF36-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AF36-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF36/entry#A0A8V1AF36-1", "sequence": { "sequence": "LGVPCAFPRRNAFPGAEGTAGPGTTTPSVPRAAGIQLPACPAPCPCGRCAREAAALAEQRCSPSGRIAPPAQRRALGGARRSGGAAFRSPVGRPPAPLAAPPPLRAGGEAPCDDVEALKEKDRALDREIAQLLSEGYSVEELEKHISLLHEYNEIKDAGQMLLGKLAVIRGVTTKQLYPEYDLELND", "length": 187, "header": "tr|A0A8V1AF36-1|A0A8V1AF36_CHICK Isoform 1 of DNA repair protein SWI5 homolog OS=Gallus gallus OX=9031 GN= PE=3 SV=1 CANONICAL=A0A8V1AF36-1" }, "locus": { "chromosome": "17", "start_pos": 5669968, "end_pos": 5668013, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068110.1", "url": "https://www.ensembl.org/id/ENSGALT00010068110.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041853.1", "url": "https://www.ensembl.org/id/ENSGALP00010041853.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AF36", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF36" } ], "pmid": "" }, { "name": "Swi5-Sfr1 complex", "id": "GO:0032798", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032798", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AF36", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF36" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "double-strand break repair via homologous recombination", "id": "GO:0000724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000724", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AF36", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF36" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], 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"PF23389", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23389", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1AF68", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF68", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AF68-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF68-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPGLRGRVESFSSPAGQYLSGTHPAVPNPGLPPPATGGQQRRVQRLLPPSPRRAAASGPRGTYGHMAASMEPTEDVERLLIQFRDEAGEPLGSPFDVPVSITPDKLQLVCNALLQQDEPVPLAFFFHDAEIIVSLEKTLAGQAVETEKVLDIIYQPQAVFRVRAVTRCTSSLEGHTEAVISVAFSPTGKYLASGSGDTTVRFWDLSTETPQFTAKGHRHWVLSIAWSPDGKKLASGCKNSQIFLWDPATGNQIGRVLTGHSKWITCLCWEPLHINPECRYLASASKDGSIRIWDTLMGRCDKILTGHTQSVTCVKWGGDGLLYSSSQDRTIKVWRSQDGILCRTLQGHAHWVNTMALSTDYVLRTGAFEPAEATINPQDMSGSLAELKDKAQQRYDKVRGQGPERLVSGSDDFTLFLWRPAEDKKPLERMTGHQALINQVLFSPDTRIIASASFDKSIKLWEGRTGKYLTSLRGHVSAVYQIAWSADSRLLVSGSSDSTLKVWDAETKKLAIDLPGHADEVFATDWSPDGQRVASGGKDKCLRIWRR", 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PE=1 SV=1 CANONICAL=A0A8V1AF68-1" }, "locus": { "chromosome": "19", "start_pos": 7284828, "end_pos": 7277579, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071984.1", "url": "https://www.ensembl.org/id/ENSGALT00010071984.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044674.1", "url": "https://www.ensembl.org/id/ENSGALP00010044674.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 166, "start_aa": "Thr", "end_pos": 166, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr166", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AF68", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF68" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "Notch signaling pathway", "id": "GO:0007219", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007219", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AF68", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF68" } ], "pmid": "" }, { "name": "regulation of Notch signaling pathway", "id": "GO:0008593", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008593", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AF68", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF68" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AF68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF68" }, { "id": "PF08154", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08154" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "NLE", "eco_id": "ECO_0000259", "start_pos": 80, "end_pos": 139, "start_aa": "Leu", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1AF68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF68" }, { "id": "PF23389", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23389" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "WDR19 first beta-propeller", "eco_id": "ECO_0000259", "start_pos": 186, "end_pos": 339, "start_aa": "Pro", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 166 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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"A0A8V1AF87_CHICK", "mass": { "chemical_mass": 77647.0, "monoisotopic_mass": 77647.0 }, "refseq": {}, "gene_names": [ { "name": "CFAP45", "type": "recommended", "evidence": [ { "id": "A0A8V1AF87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF87" } ] } ], "protein_names": [ { "name": "Cilia- and flagella-associated protein 45", "type": "recommended", "evidence": [ { "id": "A0A8V1AF87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF87/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AF87", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF87" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CFAP45", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF87", "locus": { "chromosome": "25", "start_pos": 2461823, "end_pos": 2453948, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028689", "url": "https://www.ensembl.org/id/ENSGALG00010028689" } ] } } ], "crossref": [ { "id": "A0A8V1AF87", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AF87", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR033253", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033253", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043597", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043597", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AF87", "url": "https://www.orthodb.org/?gene=A0A8V1AF87", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15504", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15504", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15504:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15504:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13868", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13868", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1AF87", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF87", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AF87-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF87-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGHPNTGTRRWESTNGDKRERDANGATQAWRRVRERPGRGTGGHGRRRAWRGRRRSSVDTAGAEHLPATIESAPRCLERPLRAGPAPARLVAMGTRGRCCGDGAAERSGMVSAARGLQGPTGTTANPSGSTKPSSRYRRRARSTEVDESLFGGPSLQPSQPHGPIVLLRDARSAPKSALGAQHRPDTIRLLSNDLIRSLVVPAEKPPPSLIIGLRDFQRIQESSRVLSKEQRAAQLAALKAQREADLEAMNERKAAAKRQALLQQSKQSDLEEEAKERAQHLLQRANRMRMEQEDEIKEFSELLLGVKCHMIRDTQILEKKQIAKEMEEEEKRLARMMEVERQKANEMQEELERRRKQELIQGRQELVKQIEKNAEERALRAEQKDQESQEVLRYLEQLKMDEQKELEQKKEQQKKIQAEIKRINDENQRCKEEQLQKERMEDERVLEYQRQKMEREAELEAEQERIRREKEKEMARLRAMQERALDQQAEKDALRAKRSQEAAEREWRRKEKEAARRKAEMEEQLRQGRSQQIAEREHCMAVQVMRDRHDFERILRAQQEQIEKEKAEEARRAALQLAHADDIRRQIQEQQQLRAQERMAAFEESRRLQEAAQQRSRRIAQLKQQKIQELRAAGIPEKYCAQVERWAQSGAQPHTEKKATAQEFRLS", "length": 668, "header": "tr|A0A8V1AF87-1|A0A8V1AF87_CHICK Isoform 1 of Cilia- and flagella-associated protein 45 OS=Gallus gallus OX=9031 GN=CFAP45 PE=3 SV=1 CANONICAL=A0A8V1AF87-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AF87-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF87/entry#A0A8V1AF87-1", "sequence": { "sequence": "MGHPNTGTRRWESTNGDKRERDANGATQAWRRVRERPGRGTGGHGRRRAWRGRRRSSVDTAGAEHLPATIESAPRCLERPLRAGPAPARLVAMGTRGRCCGDGAAERSGMVSAARGLQGPTGTTANPSGSTKPSSRYRRRARSTEVDESLFGGPSLQPSQPHGPIVLLRDARSAPKSALGAQHRPDTIRLLSNDLIRSLVVPAEKPPPSLIIGLRDFQRIQESSRVLSKEQRAAQLAALKAQREADLEAMNERKAAAKRQALLQQSKQSDLEEEAKERAQHLLQRANRMRMEQEDEIKEFSELLLGVKCHMIRDTQILEKKQIAKEMEEEEKRLARMMEVERQKANEMQEELERRRKQELIQGRQELVKQIEKNAEERALRAEQKDQESQEVLRYLEQLKMDEQKELEQKKEQQKKIQAEIKRINDENQRCKEEQLQKERMEDERVLEYQRQKMEREAELEAEQERIRREKEKEMARLRAMQERALDQQAEKDALRAKRSQEAAEREWRRKEKEAARRKAEMEEQLRQGRSQQIAEREHCMAVQVMRDRHDFERILRAQQEQIEKEKAEEARRAALQLAHADDIRRQIQEQQQLRAQERMAAFEESRRLQEAAQQRSRRIAQLKQQKIQELRAAGIPEKYCAQVERWAQSGAQPHTEKKATAQEFRLS", "length": 668, "header": "tr|A0A8V1AF87-1|A0A8V1AF87_CHICK Isoform 1 of Cilia- and flagella-associated protein 45 OS=Gallus gallus OX=9031 GN=CFAP45 PE=3 SV=1 CANONICAL=A0A8V1AF87-1" }, "locus": { "chromosome": "25", "start_pos": 2461790, "end_pos": 2454003, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069453.1", "url": "https://www.ensembl.org/id/ENSGALT00010069453.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042774.1", "url": "https://www.ensembl.org/id/ENSGALP00010042774.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "sperm end piece", "id": "GO:0097229", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097229", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AF87", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF87" } ], "pmid": "" }, { "name": "sperm principal piece", "id": "GO:0097228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097228", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AF87", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF87" } ], "pmid": "" }, { "name": "sperm midpiece", "id": "GO:0097225", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097225", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AF87", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF87" } ], "pmid": "" }, { "name": "9+0 motile cilium", "id": "GO:0097728", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097728", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AF87", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF87" } ], "pmid": "" }, { "name": "axonemal B tubule inner sheath", "id": "GO:0160112", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160112", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AF87", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF87" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "AMP binding", "id": "GO:0016208", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016208", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AF87", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF87" } ], "pmid": "" } ] }, { "name": "Biological 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Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052556.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004948293.2. 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"Protein" ] }, { "id": "A0A8V1AM91-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM91-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MALNRNHSEGGGVIVNNSESVLMTYDHVEMTFSDIEPMPEAFKGTKKGSVFLTPYRVIFVSKGKDALQSFGMAFYLLKDYEIKQPVFGANYIKGTVKAEAGGGWEGSATFKMTFTAGGAIEFGQRMLQVASQASRGEVPNGAYGYSYMPNGSYAFAPPVANGGYPYPPPPPEFYPAPPVGGADMGYMHLPPPPYPGPMEPPSAGPDLPSTPAAEAKAAEAAASAYYNPVNPHNVYMPTVSAEIKFPQGFLTWGRIRIMYKLHCRAALAVLLSDTAKCV", "length": 278, "header": "tr|A0A8V1AFC3-1|A0A8V1AFC3_CHICK Isoform 1 of WW domain binding protein 2 OS=Gallus gallus OX=9031 GN=WBP2 PE=1 SV=1 CANONICAL=A0A8V1AFC3-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AFC3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFC3/entry#A0A8V1AFC3-1", "sequence": { "sequence": 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"MKCKSARQSDLSAGLSVLMTYDHVEMTFSDIEPMPEAFKGTKKGSVFLTPYRVIFVSKGKDALQSFGMAFYLLKDYEIKQPVFGANYIKGTVKAEAGGGWEGSATFKMTFTAGGAIEFGQRMLQVASQASRGEVPNGAYGYSYMPNGSYAFAPPVANGGYPYPPPPPEFYPAPPVGGADMGYMHLPPPPYPGPMEPPSAGPDLPSTPAAEAKAAEAAASAYYNPVNPHNVYMPTPPPPPYFPPEDKKNQ", "length": 249, "header": "tr|A0A8V1AM91-1|A0A8V1AFC3_CHICK Computationally mapped isoform of WW domain binding protein 2 OS=Gallus gallus OX=9031 GN=WBP2 PE=1 SV=1 CANONICAL=A0A8V1AFC3-1" }, "locus": { "chromosome": "18", "start_pos": 5271525, "end_pos": 5267308, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010072034.1", "url": "https://www.ensembl.org/id/ENSGALT00010072034.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044724.1", "url": "https://www.ensembl.org/id/ENSGALP00010044724.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFC3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFC3" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFC3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFC3" } ], "pmid": "" }, { "name": "chromatin DNA binding", "id": "GO:0031490", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031490", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFC3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFC3" } ], "pmid": "" }, { "name": "nuclear estrogen receptor binding", "id": "GO:0030331", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030331", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFC3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFC3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFC3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFC3" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFC3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFC3" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFC3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFC3" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFC3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFC3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 8, "go_terms": [ { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFC3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFC3" } ], "pmid": "" }, { "name": "response to progesterone", "id": "GO:0032570", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032570", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFC3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFC3" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFC3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFC3" } ], "pmid": "" }, { "name": "transcription initiation-coupled chromatin remodeling", "id": "GO:0045815", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045815", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFC3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFC3" } ], "pmid": "" }, { "name": "positive regulation of intracellular estrogen receptor signaling pathway", "id": "GO:0033148", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033148", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFC3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFC3" } ], "pmid": "" }, { "name": "cellular response to estrogen stimulus", "id": "GO:0071391", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071391", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFC3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFC3" } ], "pmid": "" }, { "name": "establishment of protein localization to chromatin", "id": "GO:0071169", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071169", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFC3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFC3" } ], "pmid": "" }, { "name": "progesterone receptor signaling pathway", "id": "GO:0050847", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050847", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFC3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFC3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 150, "end_pos": 152, "annotation": "n_glycosylation_sequon" }, { "start_pos": 16, "end_pos": 18, "annotation": "n_glycosylation_sequon" }, { "start_pos": 6, "end_pos": 8, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AFC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFC3" }, { "id": "PF02893", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02893" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "GRAM", "eco_id": "ECO_0000259", "start_pos": 34, "end_pos": 131, "start_aa": "Asp", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 150, "end_pos": 152 }, { "start_pos": 16, "end_pos": 18 }, { "start_pos": 6, "end_pos": 8 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AFC8-1", "uniprot_ac": "A0A8V1AFC8", "uniprot_id": "A0A8V1AFC8_CHICK", "mass": { "chemical_mass": 45946.0, "monoisotopic_mass": 45946.0 }, "refseq": {}, "gene_names": [ { "name": "ARRDC1", "type": "recommended", "evidence": [ { "id": "A0A8V1AFC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFC8" } ] } ], "protein_names": [ { "name": "Arrestin domain containing 1", "type": "synonym", "evidence": [ { "id": "A0A8V1AFC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFC8/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFC8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ARRDC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFC8", "locus": { "chromosome": "17", "start_pos": 2657588, "end_pos": 2630806, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028743", "url": "https://www.ensembl.org/id/ENSGALG00010028743" } ] } } ], "crossref": [ { "id": "A0A8V1AFC8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AFC8", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR011021", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011021", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011022", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011022", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014752", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014752", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014756", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014756", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050357", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050357", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AFC8", "url": "https://www.orthodb.org/?gene=A0A8V1AFC8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ALK5", "url": "https://www.orthodb.org/?gene=A0A8V1ALK5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11188", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11188", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11188:SF176", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11188:SF176", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00339", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00339", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02752", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02752", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1AFC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFC8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFC8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFC8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALK5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALK5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALK5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALK5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSVQTCSPTCLQEQECLSTAVQQASSDGRLPSPAQCLGVATDAIKVSCVGFCGVSNKINDTAWTVEEQYFNSTLSLADKGVLSAGEHNFSFQFLLPASAPTSFEGPFGKVLHQVKAVIDTPRFSKDYKCNKIFYVLCPLNLNDILDIEQPNTMSVTKKFNYKLVKSGNVILTATSDLKGYIVGQVIQLRTDIENKSGRDTGAVVASLLQKVAYKSKRWIYDLRTIAEVEGSGVKAWKHAEWKEQILVPALPQSILQGCSLIHIDYYIQVSLKSPEVSVTLPIYIGNIAVNRVPLSPSRSVQHLPSAVVPSAPPEEEEAAGGYHPMDNVLIPTKSHSQQQPFSYAPGLSFQEADSEQTGSPNHPTLCLSTGATVPYYAEGNVVPVPTASSLILPPEYSTWGYPYEAPPSYEQSCSSANSSISNGN", "length": 424, "header": "tr|A0A8V1AFC8-1|A0A8V1AFC8_CHICK Isoform 1 of Arrestin domain containing 1 OS=Gallus gallus OX=9031 GN=ARRDC1 PE=1 SV=1 CANONICAL=A0A8V1AFC8-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AFC8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFC8/entry#A0A8V1AFC8-1", "sequence": { "sequence": "MSVQTCSPTCLQEQECLSTAVQQASSDGRLPSPAQCLGVATDAIKVSCVGFCGVSNKINDTAWTVEEQYFNSTLSLADKGVLSAGEHNFSFQFLLPASAPTSFEGPFGKVLHQVKAVIDTPRFSKDYKCNKIFYVLCPLNLNDILDIEQPNTMSVTKKFNYKLVKSGNVILTATSDLKGYIVGQVIQLRTDIENKSGRDTGAVVASLLQKVAYKSKRWIYDLRTIAEVEGSGVKAWKHAEWKEQILVPALPQSILQGCSLIHIDYYIQVSLKSPEVSVTLPIYIGNIAVNRVPLSPSRSVQHLPSAVVPSAPPEEEEAAGGYHPMDNVLIPTKSHSQQQPFSYAPGLSFQEADSEQTGSPNHPTLCLSTGATVPYYAEGNVVPVPTASSLILPPEYSTWGYPYEAPPSYEQSCSSANSSISNGN", "length": 424, "header": "tr|A0A8V1AFC8-1|A0A8V1AFC8_CHICK Isoform 1 of Arrestin domain containing 1 OS=Gallus gallus OX=9031 GN=ARRDC1 PE=1 SV=1 CANONICAL=A0A8V1AFC8-1" }, "locus": { "chromosome": "17", "start_pos": 2655931, "end_pos": 2641804, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069558.1", "url": "https://www.ensembl.org/id/ENSGALT00010069558.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042819.1", "url": "https://www.ensembl.org/id/ENSGALP00010042819.1" } ] } }, { "isoform_ac": "A0A8V1ALK5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFC8/entry#A0A8V1ALK5-1", "sequence": { "sequence": "EVTAGTFTSYTCCFSLTAIKVSCVGFCGVSNKINDTAWTVEEQYFNSTLSLADKGVLSAGEHNFSFQFLLPASAPTSFEGPFGKVLHQVKAVIDTPRFSKDYKCNKIFYVLCPLNLNDILDIEQPNTMSVTKKFNYKLVKSGNVILTATSDLKGYIVGQVIQLRTDIENKSGRDTGAVVASLLQKVAYKSKRWIYDLRTIAEVEGSGVKAWKHAEWKEQILVPALPQSILQGCSLIHIDYYIQVSLKSPEVSVTLPIYIGNIAVNRVPLSPSRSVQHLPSAVVPSAPPEEEEAAGGYHPMDNVLIPTKSHSQQQPFSYAPGLSFQEADSEQTGSPNHPTLCLSTGATVPYYAEGNVVPVPTASSLILPPEYSTWGYPYEAPPSYEQSCSSANSSISNGN", "length": 399, "header": "tr|A0A8V1ALK5-1|A0A8V1AFC8_CHICK Computationally mapped isoform of Arrestin domain containing 1 OS=Gallus gallus OX=9031 GN=ARRDC1 PE=1 SV=1 CANONICAL=A0A8V1AFC8-1" }, "locus": { "chromosome": "17", "start_pos": 2655931, "end_pos": 2643244, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069557.1", "url": "https://www.ensembl.org/id/ENSGALT00010069557.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042818.1", "url": "https://www.ensembl.org/id/ENSGALP00010042818.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFC8" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFC8" } ], "pmid": "" }, { "name": "cytoplasmic vesicle", "id": "GO:0031410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031410", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFC8" } ], "pmid": "" }, { "name": "extracellular vesicle", "id": "GO:1903561", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903561", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFC8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFC8" } ], "pmid": "" }, { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFC8" } ], "pmid": "" }, { "name": "ubiquitin-dependent protein catabolic process", "id": "GO:0006511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006511", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFC8" } ], "pmid": "" }, { "name": "extracellular transport", "id": "GO:0006858", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006858", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFC8" } ], "pmid": "" }, { "name": "negative regulation of Notch signaling pathway", "id": "GO:0045746", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045746", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFC8" } ], "pmid": "" }, { "name": "extracellular vesicle biogenesis", "id": "GO:0140112", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140112", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFC8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFC8" } ], "pmid": "" }, { "name": "ubiquitin protein ligase binding", "id": "GO:0031625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031625", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFC8" } ], "pmid": "" }, { "name": "arrestin family protein binding", "id": "GO:1990763", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990763", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFC8" } ], "pmid": "" }, { "name": "ubiquitin-like ligase-substrate adaptor activity", "id": "GO:1990756", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990756", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFC8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 194, "end_pos": 196, "annotation": "n_glycosylation_sequon" }, { "start_pos": 417, "end_pos": 419, "annotation": "n_glycosylation_sequon" }, { "start_pos": 59, "end_pos": 61, "annotation": "n_glycosylation_sequon" }, { "start_pos": 71, "end_pos": 73, "annotation": "n_glycosylation_sequon" }, { "start_pos": 88, "end_pos": 90, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AFC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFC8" }, { "id": "SM01017", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM01017" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Arrestin C-terminal-like", "eco_id": "ECO_0000259", "start_pos": 165, "end_pos": 289, "start_aa": "Lys", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 194, "end_pos": 196 }, { "start_pos": 417, "end_pos": 419 }, { "start_pos": 59, "end_pos": 61 }, { "start_pos": 71, "end_pos": 73 }, { "start_pos": 88, "end_pos": 90 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AFD1-1", "uniprot_ac": "A0A8V1AFD1", "uniprot_id": "A0A8V1AFD1_CHICK", "mass": { "chemical_mass": 63028.0, "monoisotopic_mass": 63028.0 }, "refseq": { "ac": "XP_004935043", "name": "TRAF3-interacting JNK-activating modulator isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004935043" }, "gene_names": [ { "name": "TRAF3IP3", "type": "recommended", "evidence": [ { "id": "A0A8V1AFD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFD1" } ] }, { "name": "TRAF3IP3", "type": "synonym", "evidence": [ { "id": "XP_004935043", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004935043" } ] } ], "protein_names": [ { "name": "TRAF3 interacting protein 3", "type": "synonym", "evidence": [ { "id": "A0A8V1AFD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFD1/entry#names_and_taxonomy" } ] }, { "name": "TRAF3-interacting JNK-activating modulator isoform X1", "type": "synonym", "evidence": [ { "id": "XP_004935043", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004935043" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052557.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004935043.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004935043", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004935043" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFD1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFD1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TRAF3IP3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFD1", "locus": { "chromosome": "26", "start_pos": 3200504, "end_pos": 3190423, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027209", "url": "https://www.ensembl.org/id/ENSGALG00010027209" } ] } } ], "crossref": [ { "id": "A0A8V1AFD1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AFD1", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd21912", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21912", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "419862", "url": "https://www.ncbi.nlm.nih.gov/gene/419862", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR051176", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051176", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:419862", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419862", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KEKEWDF", "url": "https://omabrowser.org/oma/group/KEKEWDF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AFD1", "url": "https://www.orthodb.org/?gene=A0A8V1AFD1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15715", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15715", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15715:SF21", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15715:SF21", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF27557", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27557", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004935043", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004935043", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AFD1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFD1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFD1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFD1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MISPPERARPRRAGESYEEKCERRQETREALRRRGHHAHSARRPGRPEEQPQSPRQREFLRRRNLGGTAGELSAPILLQRPWSHPMCPSTIPPLGLSSPTGILAEAIPVPHTSKSTRGTQTPASTRVKDSGQQTDCGNTVFSKEIVQLSGYLKEALHRELLLKQKMVILQELLATLLHASEKSWQGQLNEDKLKCKLRALENQLQACTQSYSKECMKKILIEMEDQKQTYEQKAKEALQKMLEDKLQAEQQLQNSQRCLAVTREDLALWKEHYTMLKSEWAQMAKAHSELKSNLHTVQSQLQHMATQNEELCQALDILQHEHAELQQHADNLQQDNQLQAKHISNIEGKLQKEQNQKLILEATISHLQNLMQNQNNEQKTQEVTVQRKDQGFTTQTPPLTPAKEVQNALSEHPKEKAEESLRDEMQERTSQLTAKEKEVCMGTRAAEGQTPPRHTAHTQVKHHKCCGSPTSAGVPEATGLPPTDPCLRSPPECQELRAELEALSEEYRCCLSCLHQCRQELNQSQTVKRKRGNWLPLLLAVIVMAVAAVLASYRP", "length": 555, "header": "tr|A0A8V1AFD1-1|A0A8V1AFD1_CHICK Isoform 1 of TRAF3 interacting protein 3 OS=Gallus gallus OX=9031 GN=TRAF3IP3 PE=4 SV=1 CANONICAL=A0A8V1AFD1-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AFD1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFD1/entry#A0A8V1AFD1-1", "sequence": { "sequence": "MISPPERARPRRAGESYEEKCERRQETREALRRRGHHAHSARRPGRPEEQPQSPRQREFLRRRNLGGTAGELSAPILLQRPWSHPMCPSTIPPLGLSSPTGILAEAIPVPHTSKSTRGTQTPASTRVKDSGQQTDCGNTVFSKEIVQLSGYLKEALHRELLLKQKMVILQELLATLLHASEKSWQGQLNEDKLKCKLRALENQLQACTQSYSKECMKKILIEMEDQKQTYEQKAKEALQKMLEDKLQAEQQLQNSQRCLAVTREDLALWKEHYTMLKSEWAQMAKAHSELKSNLHTVQSQLQHMATQNEELCQALDILQHEHAELQQHADNLQQDNQLQAKHISNIEGKLQKEQNQKLILEATISHLQNLMQNQNNEQKTQEVTVQRKDQGFTTQTPPLTPAKEVQNALSEHPKEKAEESLRDEMQERTSQLTAKEKEVCMGTRAAEGQTPPRHTAHTQVKHHKCCGSPTSAGVPEATGLPPTDPCLRSPPECQELRAELEALSEEYRCCLSCLHQCRQELNQSQTVKRKRGNWLPLLLAVIVMAVAAVLASYRP", "length": 555, "header": "tr|A0A8V1AFD1-1|A0A8V1AFD1_CHICK Isoform 1 of TRAF3 interacting protein 3 OS=Gallus gallus OX=9031 GN=TRAF3IP3 PE=4 SV=1 CANONICAL=A0A8V1AFD1-1" }, "locus": { "chromosome": "26", "start_pos": 3200340, "end_pos": 3191763, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065961.1", "url": "https://www.ensembl.org/id/ENSGALT00010065961.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040227.1", "url": "https://www.ensembl.org/id/ENSGALP00010040227.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:419862", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419862", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287A6X1-1", "protein_name": "TRAF3 interacting protein 3", "gene_name": "TRAF3IP3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLSPDPRPAPGLARWAESYEAKCERRQETRESRRRRPNVTTCRQVGKALRTQQREQFQKARQQQFFRLRHLEVEEKGQAERSQTRQPGSSRAGQAPDLKEPWPWANRISSPGQQVSGTSAEVFPAQRHPPSGARRDSAVQKLPKQHRGTQTKAEETQPTTKNDASQQTNYGVAVLDKEIIQLSEYLKEALHRELVLKQKMVILQDLLSTLIQASDSSWKGQLNEDKLKGKLRSLENQLYTCTQNYSPRGMKKVILEMEDQKHSYEQKAKESLQKVLEEKMSAEQQLQSTQRSLALAEQKCEEWRSQYEALKEDWRTLGTQHRELESQLHVLQSKLQGADSRDLQMNQALRLLENEHQELQAKIARLQGDRDLCSSDTQHLQDQLQKSEEEKLALVTKVQQLQSLLQSQSLQLQEQEKRLTKKDQALEWSPKPSQNEVEPEGPGKEKDWDFRDQLQEKTLQLLAKEKECRDLHSELDNLSDEYLSCLRKLQRCREELSLGQRPPPTRQCGRWLPALMVLTAMALAVFLAHKDSLMI", "length": 535 }, "evidence": [ { "id": "A0A8V1AFD1", "url": "https://omabrowser.org/oma/group/A0A8V1AFD1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F6RMH4-1", "protein_name": "TRAF3 interacting protein 3", "gene_name": "TRAF3IP3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRAGKSVHRTDLQDLEFQTPHTHTPATFCRMWTAKPTSKAAVQKERQYQEGKRSGGPEPWIEILPLCGDHSQDLPRSWDAFLICWGWRLGPQTRAAIPGTGSQATTGAQEVIMIGPDPRPAPGLARWAESYEAKSERRQETRESRRCRPNVTTCRLVGKAPRTQQREQLRRARQQQFFRRRNLEVEEKGEAQSPPAREPGPSRRTGQATDLKEPLSWANRISSPRQQVSGTSCEVFATQHHPPSGAWRDPAGHCPTQAGGLPPQASPTKKAPKHHRGTQTKAGETQSTIKNDASQQTNYGVAVLDKEIIQLSEYLKEALQRELILKQKMVILQDLLSTLIQASDSTWKGQLNEDKLKGKLRSLENQLYACTQKYSPWGMKKVLLEMEDQKNSYEQKAKESLQKVLEEKMSAEQQLQSTQRSLALAEQKCEEWKSQYEALKEDWRTLGTQHRELESQLHVLQSKLQGADSRDSQMNQALRLLESEHQELQARIECLQEDRDLCSSDTQHLQDQLKRSEEEKLALVTKVQQLQSLLQNQSLQLQKQEKLLTKKDQALPVRSPEPSHNEVEPEGPGKEQDLDFRDELQKKTLQLLAKEKECRELLSELDNLSDEYLSCLRKLQHCREELSQSQQPPPRRQCGRWLLMLMALAAIAVAVMLANKDSLMLW", "length": 666 }, "evidence": [ { "id": "A0A8V1AFD1", "url": "https://omabrowser.org/oma/group/A0A8V1AFD1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8C0G2-1", "protein_name": "TRAF3-interacting JNK-activating modulator", "gene_name": "Traf3ip3", "tax_id": 10090, 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"MISPDPRPSPGLARWAESYEAKCERRQEIRESRRCRPNVTTCRQVGKTLRIQQREQLQRARLQQFFRRRNLELEEKGKAQHPQAREQGPSRRPGQVTVLKEPLSCARRISSPREQVTGTSSEVFPAQHPPPSGICRDLSDHLSSQAGGLPPQDTPIKKPPKHHRGTQTKAEGPTIKNDASQQTNYGVAVLDKEIIQLSDYLKEALQRELVLKQKMVILQDLLSTLIQASDSSWKGQLNEDKLKGKLRSLENQLYTCTQKYSPWGMKKVLLEMEDQKNSYEQKAKESLQKVLEEKMNAEQQLQSTQRSLALAEQKCEEWRSQYEALKEDWRTLGTQHRELESQLHVLQSKLQGADSRDLQMNQALRFLENEHQQLQAKIECLQGDRDLCSLDTQDLQDQLKRSEAEKLTLVTRVQQLQGLLQNQSLQLQEQEKLLTKKDQALPVWSPKSFPNEVEPEGTGKEKDWDLRDQLQKKTLQLQAKEKECRELHSELDNLSDEYLSCLRKLQHCREELNQSQQLPPRRQCGRWLPVLMVVIAAALAVFLANKDNLMI", "length": 551 }, "evidence": [ { "id": "A0A8V1AFD1", "url": "https://omabrowser.org/oma/group/A0A8V1AFD1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "molecular adaptor activity", "id": "GO:0060090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060090", "evidence": [ { "database": "UniProtKB", "id": 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"ac": "XP_040508498", "name": "claw keratin-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040508498" }, "gene_names": [ { "name": "LOC121107575", "type": "recommended", "evidence": [ { "id": "A0A8V1AFD9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFD9" } ] }, { "name": "LOC121107575", "type": "synonym", "evidence": [ { "id": "XP_040508498", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040508498" } ] } ], "protein_names": [ { "name": "Keratin", "type": "recommended", "evidence": [ { "id": "A0A8V1AFD9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFD9/entry#names_and_taxonomy" } ] }, { "name": "claw keratin-like", "type": "synonym", "evidence": [ { "id": "XP_040508498", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040508498" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052556.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040508498", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040508498" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFD9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFD9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC121107575", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFD9", "locus": {} } ], "crossref": [ { "id": "121107575", "url": "https://www.ncbi.nlm.nih.gov/gene/121107575", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003461", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003461", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:426217", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:426217", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YLNGNCA", "url": "https://omabrowser.org/oma/group/YLNGNCA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AFD9", "url": "https://www.orthodb.org/?gene=A0A8V1AFD9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31203", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31203", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31203:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31203:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02422", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02422", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040508498", "url": 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}, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AFE0-1", "uniprot_ac": "A0A8V1AFE0", "uniprot_id": "A0A8V1AFE0_CHICK", "mass": { "chemical_mass": 247233.0, "monoisotopic_mass": 247233.0 }, "refseq": { "ac": "XP_024997276", "name": "protein PRRC2B isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024997276" }, "gene_names": [ { "name": "PRRC2B", "type": "recommended", "evidence": [ { "id": "A0A8V1AFE0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFE0" } ] }, { "name": "PRRC2B", "type": "synonym", "evidence": [ { "id": "XP_024997276", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024997276" } ] } ], "protein_names": [ { "name": "Proline rich coiled-coil 2B", "type": "synonym", "evidence": [ { "id": "A0A8V1AFE0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFE0/entry#names_and_taxonomy" } ] }, { "name": "protein PRRC2B isoform X2", "type": "synonym", "evidence": [ { "id": "XP_024997276", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024997276" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052548.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_024997276.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_024997276", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024997276" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFE0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFE0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PRRC2B", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFE0", "locus": { "chromosome": "17", "start_pos": 6822555, "end_pos": 6778688, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028157", "url": "https://www.ensembl.org/id/ENSGALG00010028157" } ] } } ], "crossref": [ { "id": "417177", "url": "https://www.ncbi.nlm.nih.gov/gene/417177", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR009738", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009738", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033184", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033184", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AFE0", "url": "https://www.orthodb.org/?gene=A0A8V1AFE0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AHR2", "url": "https://www.orthodb.org/?gene=A0A8V1AHR2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14038", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14038", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14038:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14038:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07001", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07001", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_024997276", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024997276", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AFE0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFE0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFE0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFE0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHR2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHR2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHR2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHR2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSDRLGQITKGKDGKSKYSTLSLFDKYKGKSIEAIRTTVIPRHGLQSLGKVAAARRMPPPANLPSLKSENKGNDPNIVIVPKDGTGWANKQDQSDQKNSSATAAQLQESLLQQGLQKSVSNLQKPTQSIAQESTNSVPGGPKSWAQLNGKPAGLEGGSRASSRLLSFSPEEFPTLKAAGEQDKVGKEKGALDLSYGPGPSLRPQNVTSWREGGGRNITSATSLTASPAELGSKTSSTGDGAPSSVSASDPKEPSLRPAQPVRKGASQFMGNVYQPPTYHDMLPAFMCPQQPSETPAPLDRGSFPVPQLRLEPRVPFRQYQMNDQDGKENRLGLSRPARPLRQLVERAPRPTIINAENLKGLDELDNDADDGWAGIHDEVDYSEKLKFSEDEEEEESLKDGRQKWNSWDPRRQRQLSMSSADSADVKHTLEEGKNWSDSVGLSRSVRKAQDSQQPPRKINGWNSTSEYQKPSQGSALRQQSLEDKEEKVPLRQKFVHSEISEAVERARKRREEEERRAREERLAACAAKLKQLDQKCKLAQKSGETQKHTENEDLRPPNTEKSAVQENGHVFRRATPEFHTQDVSGYLEEETPAPAAPQSSSEDELREAPSPAQEFSKYQKSLPPRFQRQQQQEQLYKMQHWQQQQVYPPPSHSHRTFYPPHPQMLGFDPRWMMMPSYLDPRMAQSRTPVDFYPSALHPSGIMKPMIQQDSIGGNSCRSEDQNCQAGQVERKAAPMDPVPVWGQESYASLQSKGYSLSHQKQSDNMTMEGLHARNGSSYSSSPGRPENLNTQRDLFEERGEEYLNAFDKKTQGDFDSCLSSQRLGQDLLFQHQESVQETCPSSNRHANLRCSPLEPDFIQAEKKPEYNGWDISHHQKPSEPAAEITEEVPRNEQSFAADPWKKEGASNTKQPAEETAEWAPENRSTGVQQQEQIGRTRRSGPIKKPVLKALKVEEKEKEMEKVKLEGEDTSRHLKEKVTVQKVENESDDSAALLNSTRYLLDDKGSSQASLAREAEKSQEEEEEEEEEDKPERTWENKVSRESSELPPTKRNNWIFIDEEQAFGGRGQGRGRGRGFREFTFRGRGTVVSSRGVYNNQRSSRGRGLREFNQPEDFPRGKPRRRIASETHSEGSEYEELPKRRRQRGSENSNDGSVLDREDSDLKKGDFKESWRSNKIYSDDHTSLDPKMRAPRAFGRSLPPRLSNSGYGRRGFMGKEPTQWQGRSGGAGWQEYSHTSPSDGFGSRQQSDRDYIQDSYKHVDSFSSRVFDESHLDDKRHFFQEDYLADQENIENRPFRRRRPPRQDKPPRFRRLRQERELVGQWNPEEGGPNLLPSQWPGRPKLSTTEKSSISGRRSPELSYQNSSDHANEEWETASESSDFSERRERRDGVSESEGQLESGLGSGSLGEKRELAKRSFSSQRPLVDRQNRKAEPAGYAEQSVRTVGAASRYESQQNGTLIKSKRSPEEGGGLGNTSGGSSHSIYSLDRASLANSESAEGPGKKSEKEPKSAVQRASEKGETLSQFELNYGSTIIDNRVSSTAEENEVGSMAGEGFIEVLTKKQRRLLEEERRKKEQAAQAPAKARVLQSRIPPRFAKKQNSLCLEQSDVTVSGNSLGTEIWESNSPALSVQSPGSDSWSKPVNTFNGTESSSTEGFKGSQGDSGIDLSAESRESSATSSQRSSPYGTLKPEEMNGAGLVDPKPDCQKEQVQKQSDKKDSDQGSGQNKEHKPGPIGNERSLKNRKGSEGTERLEGNIPPVNGVEIHVDSVLPVPPIEFGVNPKDSDFSLPPGSASGTAANPVTKLQDALASNAGLTQSIPILRRDHHLQRCIGLNPMSFPTAELTLKMESARKAWENSPSLPEQNSPGGAGSGIQPPSSVGASNGVSYSSFGGVSMPPMPVASVAPSASIPGNHIPPLYLDGHVFASQPRLVPQTIPQQQSYQQAAAAQQIPISLHTSLQAQAQLGLRGGLPVSQSQEMYSSIQPFRSQVYMHPSLSQPSTMVLTGGTALKPPYSAFPGMQPLEVVKTQSGSPYQPLNGSQTLVYEGQINQAAGMGASQMMDSQLTQLTMPVPGSQLPLPRYGSGQQPLILPQSIQLPQGQNLSVGAPRRILPPGSQPSVLAASRESSQMEMKGFHFSDGKQNMSSGGSVPSPHAYRIYSMNVVDSSISRPSSASPNGKPSGPAVSMGSVQGHYVQQAKQRVDENKANLGAVKLQETASTSQMKPVRTGAIKPQAVKVEESKA", "length": 2240, "header": "tr|A0A8V1AFE0-1|A0A8V1AFE0_CHICK Isoform 1 of Proline rich coiled-coil 2B OS=Gallus gallus OX=9031 GN=PRRC2B PE=4 SV=1 CANONICAL=A0A8V1AFE0-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AFE0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFE0/entry#A0A8V1AFE0-1", "sequence": { "sequence": "MSDRLGQITKGKDGKSKYSTLSLFDKYKGKSIEAIRTTVIPRHGLQSLGKVAAARRMPPPANLPSLKSENKGNDPNIVIVPKDGTGWANKQDQSDQKNSSATAAQLQESLLQQGLQKSVSNLQKPTQSIAQESTNSVPGGPKSWAQLNGKPAGLEGGSRASSRLLSFSPEEFPTLKAAGEQDKVGKEKGALDLSYGPGPSLRPQNVTSWREGGGRNITSATSLTASPAELGSKTSSTGDGAPSSVSASDPKEPSLRPAQPVRKGASQFMGNVYQPPTYHDMLPAFMCPQQPSETPAPLDRGSFPVPQLRLEPRVPFRQYQMNDQDGKENRLGLSRPARPLRQLVERAPRPTIINAENLKGLDELDNDADDGWAGIHDEVDYSEKLKFSEDEEEEESLKDGRQKWNSWDPRRQRQLSMSSADSADVKHTLEEGKNWSDSVGLSRSVRKAQDSQQPPRKINGWNSTSEYQKPSQGSALRQQSLEDKEEKVPLRQKFVHSEISEAVERARKRREEEERRAREERLAACAAKLKQLDQKCKLAQKSGETQKHTENEDLRPPNTEKSAVQENGHVFRRATPEFHTQDVSGYLEEETPAPAAPQSSSEDELREAPSPAQEFSKYQKSLPPRFQRQQQQEQLYKMQHWQQQQVYPPPSHSHRTFYPPHPQMLGFDPRWMMMPSYLDPRMAQSRTPVDFYPSALHPSGIMKPMIQQDSIGGNSCRSEDQNCQAGQVERKAAPMDPVPVWGQESYASLQSKGYSLSHQKQSDNMTMEGLHARNGSSYSSSPGRPENLNTQRDLFEERGEEYLNAFDKKTQGDFDSCLSSQRLGQDLLFQHQESVQETCPSSNRHANLRCSPLEPDFIQAEKKPEYNGWDISHHQKPSEPAAEITEEVPRNEQSFAADPWKKEGASNTKQPAEETAEWAPENRSTGVQQQEQIGRTRRSGPIKKPVLKALKVEEKEKEMEKVKLEGEDTSRHLKEKVTVQKVENESDDSAALLNSTRYLLDDKGSSQASLAREAEKSQEEEEEEEEEDKPERTWENKVSRESSELPPTKRNNWIFIDEEQAFGGRGQGRGRGRGFREFTFRGRGTVVSSRGVYNNQRSSRGRGLREFNQPEDFPRGKPRRRIASETHSEGSEYEELPKRRRQRGSENSNDGSVLDREDSDLKKGDFKESWRSNKIYSDDHTSLDPKMRAPRAFGRSLPPRLSNSGYGRRGFMGKEPTQWQGRSGGAGWQEYSHTSPSDGFGSRQQSDRDYIQDSYKHVDSFSSRVFDESHLDDKRHFFQEDYLADQENIENRPFRRRRPPRQDKPPRFRRLRQERELVGQWNPEEGGPNLLPSQWPGRPKLSTTEKSSISGRRSPELSYQNSSDHANEEWETASESSDFSERRERRDGVSESEGQLESGLGSGSLGEKRELAKRSFSSQRPLVDRQNRKAEPAGYAEQSVRTVGAASRYESQQNGTLIKSKRSPEEGGGLGNTSGGSSHSIYSLDRASLANSESAEGPGKKSEKEPKSAVQRASEKGETLSQFELNYGSTIIDNRVSSTAEENEVGSMAGEGFIEVLTKKQRRLLEEERRKKEQAAQAPAKARVLQSRIPPRFAKKQNSLCLEQSDVTVSGNSLGTEIWESNSPALSVQSPGSDSWSKPVNTFNGTESSSTEGFKGSQGDSGIDLSAESRESSATSSQRSSPYGTLKPEEMNGAGLVDPKPDCQKEQVQKQSDKKDSDQGSGQNKEHKPGPIGNERSLKNRKGSEGTERLEGNIPPVNGVEIHVDSVLPVPPIEFGVNPKDSDFSLPPGSASGTAANPVTKLQDALASNAGLTQSIPILRRDHHLQRCIGLNPMSFPTAELTLKMESARKAWENSPSLPEQNSPGGAGSGIQPPSSVGASNGVSYSSFGGVSMPPMPVASVAPSASIPGNHIPPLYLDGHVFASQPRLVPQTIPQQQSYQQAAAAQQIPISLHTSLQAQAQLGLRGGLPVSQSQEMYSSIQPFRSQVYMHPSLSQPSTMVLTGGTALKPPYSAFPGMQPLEVVKTQSGSPYQPLNGSQTLVYEGQINQAAGMGASQMMDSQLTQLTMPVPGSQLPLPRYGSGQQPLILPQSIQLPQGQNLSVGAPRRILPPGSQPSVLAASRESSQMEMKGFHFSDGKQNMSSGGSVPSPHAYRIYSMNVVDSSISRPSSASPNGKPSGPAVSMGSVQGHYVQQAKQRVDENKANLGAVKLQETASTSQMKPVRTGAIKPQAVKVEESKA", "length": 2240, "header": "tr|A0A8V1AFE0-1|A0A8V1AFE0_CHICK Isoform 1 of Proline rich coiled-coil 2B OS=Gallus gallus OX=9031 GN=PRRC2B PE=4 SV=1 CANONICAL=A0A8V1AFE0-1" }, "locus": { "chromosome": "17", "start_pos": 6821810, "end_pos": 6791406, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068226.1", "url": "https://www.ensembl.org/id/ENSGALT00010068226.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041969.1", "url": "https://www.ensembl.org/id/ENSGALP00010041969.1" } ] } }, { "isoform_ac": "A0A8V1AHR2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFE0/entry#A0A8V1AHR2-1", "sequence": { "sequence": "MSDRLGQITKGKDGKSKYSTLSLFDKYKGKSIEAIRTTVIPRHGLQSLGKVAAARRMPPPANLPSLKSENKGNDPNIVIVPKDGTGWANKQDQSDQKNSSATAAQLQESLLQQGLQKSVSNLQKPTQSIAQESTNSVPGGPKSWAQLNGKPAGLEGGSRASSRLLSFSPEEFPTLKAAGEQDKVGKEKGALDLSYGPGPSLRPQNVTSWREGGGRNITSATSLTASPAELGSKTSSTGDGAPSSVSASDPKEPSLRPAQPVRKGASQFMGNVYQPPTYHDMLPAFMCPQQPSETPAPLDRGSFPVPQLRLEPRVPFRQYQMNDQDGKENRLGLSRPARPLRQLVERAPRPTIINAENLKGLDELDNDADDGWAGIHDEVDYSEKLKFSEDEEEEESLKDGRQKWNSWDPRRQRQLSMSSADSADVKHTLEEGKNWSDSVGLSRSVRKAQDSQQPPRKINGWNSTSEYQKPSQGSALRQQSLEDKEEKVPLRQKFVHSEISEAVERARKRREEEERRAREERLAACAAKLKQLDQKCKLAQKSGETQKHTENEDLRPPNTEKSAVQENGHVFRRATPEFHTQDVSGYLEEETPAPAAPQSSSEDELREAPSPAQEFSKYQKSLPPRFQRQQQQEQLYKMQHWQQQQVYPPPSHSHRTFYPPHPQMLGFDPRWMMMPSYLDPRMAQSRTPVDFYPSALHPSGIMKPMIQQDSIGGNSCRSEDQNCQAGQVERKAAPMDPVPVWGQESYASLQSKGYSLSHQKQSDNMTMEGLHARNGSSYSSSPGRPENLNTQRDLFEERGEEYLNAFDKKTQGDFDSCLSSQRLGQDLLFQHQESVQETCPSSNRHANLRCSPLEPDFIQAEKKPEYNGWDISHHQKPSEPAAEITEEVPRNEQSFAADPWKKEGASNTKQPAEETAEWAPENRSTGVQQQEQIGRTRRSGPIKKPVLKALKVEEKEKEMEKVKLEGEDTSRHLKEKVTVQKVENESDDSAALLNSTRYLLDDKGSSQASLAREAEKSQEEEEEEEEEDKPERTWENKVSRESSELPPTKRNNWIFIDEEQAFGGRGQGRGRGRGFREFTFRGRGTVVSSRGVYNNQRSSRGRGLREFNQPEDFPRGKPRRRIASETHSEGSEYEELPKRRRQRGSENSNDGSVLDREDSDLKKGDFKESWRSNKIYSDDHTSLDPKMRAPRAFGRSLPPRLSNSGYGRRGFMGKEPTQWQGRSGGAGWQEYSHTSPSDGFGSRQQSDRDYIQDSYKHVDSFSSRVFDESHLDDKRHFFQEDYLADQENIENRPFRRRRPPRQDKPPRFRRLRQERELVGQWNPEEGGPNLLPSQWPGRPKLSTTEKSSISGRRSPELSYQNSSDHANEEWETASESSDFSERRERRDGVSESEGQLESGLGSGSLGEKRELAKRSFSSQRPLVDRQNRKAEPAGYAEQSVRTVGAASRYESQQNGTLIKSKRSPEEGGGLGNTSGGSSHSIYSLDRASLANSESAEGPGKKSEKEPKSAVQRASEKGETLSQFELNYGSTIIDNRVSSTAEENEVGSMAGEGFIEVLTKKQRRLLEEERRKKEQAAQAPAKARVLQSRIPPRFAKKQNSLCLEQSDVTVSGNSLGTEIWESNSPALSVQSPGSDSWSKPVNTFNGTESSSTEGFKGSQGDSGIDLSAESRESSATSSQRSSPYGTLKPEEMNGAGLVDPKPDCQKEQVQKQSDKKDSDQGSGQNKEHKPGPIGNERSLKNRKGSEGTERLEGNIPPVNGVEIHVDSVLPVPPIEFGVNPKDSDFSLPPGSASGTAANPVTKLQDALASNAGLTQSIPILRRDHHLQRCIGLNPMSFPTAELTLKMESARKAWENSPSLPEQNSPGGAGSGIQPPSSVGASNGVSYSSFGGVSMPPMPVASVAPSASIPGNHIPPLYLDGHVFASQPRLVPQTIPQQQSYQQAAAAQQIPISLHTSLQAQAQLGLRGGLPVSQSQEMYSSIQPFRSQVYMHPSLSQPSTMVLTGGTALKPPYSAFPGMQPLEVVKTQSGSPYQPLNGSQTLVYEGQINQAAGMGASQMMDSQLTQLTMPVPGSQLPLPRYGSGQQPLILPQSIQLPQGQNLSVGAPRRILPPGSQPSVLAASRESSQMEMKGFHFSDGKQNMSSGGSVPSPHAYRIYSMNVVDSSISRPSSASPNGKPSGPAVSMGSVQGHYVQQVVYVSSLTQ", "length": 2203, "header": "tr|A0A8V1AHR2-1|A0A8V1AFE0_CHICK Computationally mapped isoform of Proline rich coiled-coil 2B OS=Gallus gallus OX=9031 GN=PRRC2B PE=4 SV=1 CANONICAL=A0A8V1AFE0-1" }, "locus": { "chromosome": "17", "start_pos": 6821315, "end_pos": 6791406, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068225.1", "url": "https://www.ensembl.org/id/ENSGALT00010068225.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041968.1", "url": "https://www.ensembl.org/id/ENSGALP00010041968.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFE0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFE0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1361, "end_pos": 1363, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1454, "end_pos": 1456, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1472, "end_pos": 1474, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1644, "end_pos": 1646, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2035, "end_pos": 2037, "annotation": "n_glycosylation_sequon" }, { "start_pos": 205, "end_pos": 207, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2099, "end_pos": 2101, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2140, "end_pos": 2142, "annotation": "n_glycosylation_sequon" }, { "start_pos": 216, "end_pos": 218, "annotation": "n_glycosylation_sequon" }, { "start_pos": 434, "end_pos": 436, "annotation": "n_glycosylation_sequon" }, { "start_pos": 462, "end_pos": 464, "annotation": "n_glycosylation_sequon" }, { "start_pos": 764, "end_pos": 766, "annotation": "n_glycosylation_sequon" }, { "start_pos": 774, "end_pos": 776, "annotation": "n_glycosylation_sequon" }, { "start_pos": 922, "end_pos": 924, "annotation": "n_glycosylation_sequon" }, { "start_pos": 984, "end_pos": 986, "annotation": "n_glycosylation_sequon" }, { "start_pos": 98, "end_pos": 100, "annotation": "n_glycosylation_sequon" }, { "start_pos": 994, "end_pos": 996, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AFE0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFE0" }, { "id": "PF07001", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07001" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BAT2 N-terminal", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 189, "start_aa": "Met", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1361, "end_pos": 1363 }, { "start_pos": 1454, "end_pos": 1456 }, { "start_pos": 1472, "end_pos": 1474 }, { "start_pos": 1644, "end_pos": 1646 }, { "start_pos": 2035, "end_pos": 2037 }, { "start_pos": 205, "end_pos": 207 }, { "start_pos": 2099, "end_pos": 2101 }, { "start_pos": 2140, "end_pos": 2142 }, { "start_pos": 216, "end_pos": 218 }, { "start_pos": 434, "end_pos": 436 }, { "start_pos": 462, "end_pos": 464 }, { "start_pos": 764, "end_pos": 766 }, { "start_pos": 774, "end_pos": 776 }, { "start_pos": 922, "end_pos": 924 }, { "start_pos": 984, "end_pos": 986 }, { "start_pos": 98, "end_pos": 100 }, { "start_pos": 994, "end_pos": 996 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AFE4-1", "uniprot_ac": "A0A8V1AFE4", "uniprot_id": "A0A8V1AFE4_CHICK", "mass": { "chemical_mass": 73006.0, "monoisotopic_mass": 73006.0 }, "refseq": {}, "gene_names": [ { "name": "MTMR11", "type": "recommended", "evidence": [ { "id": "A0A8V1AFE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFE4" } ] } ], "protein_names": [ { "name": "Myotubularin related protein 11", "type": "synonym", "evidence": [ { "id": "A0A8V1AFE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFE4/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFE4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFE4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MTMR11", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFE4", "locus": { "chromosome": "25", "start_pos": 676575, "end_pos": 668479, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028752", "url": "https://www.ensembl.org/id/ENSGALG00010028752" } ] } } ], "crossref": [ { "id": "A0A8V1AFE4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AFE4", "database": "AlphaFoldDB", "categories": [] }, { "id": "100857251", "url": "https://www.ncbi.nlm.nih.gov/gene/100857251", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR010569", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010569", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022587", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022587", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029021", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029021", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030564", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030564", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "GWQRSQD", "url": "https://omabrowser.org/oma/group/GWQRSQD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AFE4", "url": "https://www.orthodb.org/?gene=A0A8V1AFE4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ALL5", "url": "https://www.orthodb.org/?gene=A0A8V1ALL5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10807", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10807", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10807:SF51", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10807:SF51", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06602", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06602", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12578", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12578", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1AFE4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFE4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFE4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFE4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALL5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALL5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALL5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALL5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSAARGGLSALPVLPGEVVLEAARGVRHRGAGGSVRGTLLCTNVRVAFVPGAQPPSFSPFLQSDYSVALRCIRTLVAASSFTKPTVLTATSTLSFIPEELAVFCRDFRLLRFHFPENGLGLQAFRVANAIAQAWETATWPGDSGSHVDATMGDDEDEEEGSPPTLLFESLQDWERELQRLGAVGWRVSAVNERFDMAPSLPRYLWVPSALLDHDLKRTFAHFQERRVARLCWHHPNGSDLLRAAGFHAASEPGSEDIRCLEVLLGAGCRPCVLADTAELPSPPDIQLAHLRLRALCLPGAAADEKWLSALEGTRWLEHIRACLRKAVEVASLLAGRRCSVVLQEPSDRDLSCLLASLVQLLADPHARSLRGFQSLVQREWVAAGHPFPQRLGLRRDSPREESPVFLLFLDCTWQLLRQFPAAFGFTEAYLLALHDSAFLPYCSTFLFSCQRQRGRGGVQQPRTQTYTPVSSRWDPPGSTVCRLPPVWAWGLRYSRQQRARFRNPAWDPGPVGTPDAVDPQNTGTPSSTWSGSSSGAVLALSKGSLTPQPFPWRSGRPPPRLLRWAPSLETLSDRGGDPIPPPPRGLLLPCAAGPSVRLWRRCYLRGLPEAQHGRLAPCPALLLEELALLQERLRAWQQDGAHAEPASSPLAPSRQRRVAAIGGAR", "length": 665, "header": "tr|A0A8V1AFE4-1|A0A8V1AFE4_CHICK Isoform 1 of Myotubularin related protein 11 OS=Gallus gallus OX=9031 GN=MTMR11 PE=3 SV=1 CANONICAL=A0A8V1AFE4-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AFE4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFE4/entry#A0A8V1AFE4-1", "sequence": { "sequence": "MSAARGGLSALPVLPGEVVLEAARGVRHRGAGGSVRGTLLCTNVRVAFVPGAQPPSFSPFLQSDYSVALRCIRTLVAASSFTKPTVLTATSTLSFIPEELAVFCRDFRLLRFHFPENGLGLQAFRVANAIAQAWETATWPGDSGSHVDATMGDDEDEEEGSPPTLLFESLQDWERELQRLGAVGWRVSAVNERFDMAPSLPRYLWVPSALLDHDLKRTFAHFQERRVARLCWHHPNGSDLLRAAGFHAASEPGSEDIRCLEVLLGAGCRPCVLADTAELPSPPDIQLAHLRLRALCLPGAAADEKWLSALEGTRWLEHIRACLRKAVEVASLLAGRRCSVVLQEPSDRDLSCLLASLVQLLADPHARSLRGFQSLVQREWVAAGHPFPQRLGLRRDSPREESPVFLLFLDCTWQLLRQFPAAFGFTEAYLLALHDSAFLPYCSTFLFSCQRQRGRGGVQQPRTQTYTPVSSRWDPPGSTVCRLPPVWAWGLRYSRQQRARFRNPAWDPGPVGTPDAVDPQNTGTPSSTWSGSSSGAVLALSKGSLTPQPFPWRSGRPPPRLLRWAPSLETLSDRGGDPIPPPPRGLLLPCAAGPSVRLWRRCYLRGLPEAQHGRLAPCPALLLEELALLQERLRAWQQDGAHAEPASSPLAPSRQRRVAAIGGAR", "length": 665, "header": "tr|A0A8V1AFE4-1|A0A8V1AFE4_CHICK Isoform 1 of Myotubularin related protein 11 OS=Gallus gallus OX=9031 GN=MTMR11 PE=3 SV=1 CANONICAL=A0A8V1AFE4-1" }, "locus": { "chromosome": "25", "start_pos": 676279, "end_pos": 668547, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069573.1", "url": "https://www.ensembl.org/id/ENSGALT00010069573.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042834.1", "url": "https://www.ensembl.org/id/ENSGALP00010042834.1" } ] } }, { "isoform_ac": "A0A8V1ALL5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFE4/entry#A0A8V1ALL5-1", "sequence": { "sequence": "MSAARGGLSALPVLPGEVVLEAARGVRHRGAGGSVRGTLLCTNVRVAFVPGAQPPSFSPFLQSDYSVALRCIRTLVAASSFTKPTVLTATSTLSFIPEELAVFCRDFRLLRFHFPENGLGLQAFRVANAIAQAWETATWPGDSGSHVDATMGDDEDEEEGSPPTLLFESLQDWERELQRLGAVGWRVSAVNERFDMAPSLPRYLWVPSALLDHDLKRTFAHFQERRVARLCWHHPNGSDLLRAAGFHAASEPGSEDIRCLEVLLGAGCRPCVLADTAELPSPPDIQLAHLRLRALCLPGAAADEKWLSALEGTRWLEHIRACLRKAVEVASLLAGRRCSVVLQEPSDRDLSCLLASLVQLLADPHARSLRGFQSLVQREWVAAGHPFPQRLGLRRDSPREESPVFLLFLDCTWQLLRQFPAAFGFTEAYLLALHDSAFLPYCSTFLFSCQRQRGRGGVQQPRTQTYTPVSSRWDPPGSTVCRLPPVWAWGLRYSRQQRARFRNPAWDPGPVGTPDAVDPQNTGTPSSTWSGSSSGAVLALSKGSLTPQPFPWRSGRPPPRLLRWAPSLETLSDRGGDPIPPPPRGLLLPCAAGPSVRLWRRCYLRGLPEAQHGRLAPCPALLLEELALLQERLRAWQQDGAHAEPASSPLAPSR", "length": 654, "header": "tr|A0A8V1ALL5-1|A0A8V1AFE4_CHICK Computationally mapped isoform of Myotubularin related protein 11 OS=Gallus gallus OX=9031 GN=MTMR11 PE=3 SV=1 CANONICAL=A0A8V1AFE4-1" }, "locus": { "chromosome": "25", "start_pos": 675555, "end_pos": 668547, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069572.1", "url": "https://www.ensembl.org/id/ENSGALT00010069572.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042833.1", "url": "https://www.ensembl.org/id/ENSGALP00010042833.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A4FU01-1", "protein_name": "Myotubularin-related protein 11", "gene_name": "MTMR11", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MWWGGRGQSFNIAPQKEEPEMGSVQENRMPEPRSRQPSSCLASRCLPGEQILAWAPGVRKGLEPELSGTLICTNFRVTFQPCGWQWNQDTPLNSEYDFALVNIGRLEAVSGLSRVQLLRPGSLHKFIPEEILIHGRDFRLLRVGFEAGGLEPQAFQVTMAIVQARAQSNQAQQYSGITLSKAGQGSGSRKPPIPLMETAEDWETERKKQAARGWRVSTVNERFDVATSLPRYFWVPNRILDSEVRRAFGHFHQGRGPRLSWHHPGGSDLLRCGGFYTASDPNKEDIRAVELMLQAGHSDVVLVDTMDELPSLADVQLAHLRLRALCLPDSSVAEDKWLSALEGTRWLDYVRACLRKASDISVLVTSRVRSVILQERGDRDLNGLLSSLVQLLSAPEARTLFGFQSLVQREWVAAGHPFLTRLGGTGASEEAPVFLLFLDCVWQLLQQFPADFEFSEFFLLALHDSVRVPDTLTFLRNTPWERGKQSGQLNSYTQVYTPGYSQPPAGNSFNLQLSVWDWDLRYSNAQILQFQNPGYDPEHCPDSWLPRPQPSFMVPGPPSSVWLFSRGALTPLNQLCPWRDSPSLLAVSSRWLPRPAISSESLADQEWGLPSHWGACPLPPGLLLPGYLGPQIRLWRRCYLRGRPEVQMGLSAPTISGLQDELSHLQELLRKWTPRISPEDHSKKRDPHTILNPTEIAGILKGRAEGDLG", "length": 709 }, "evidence": [ { "id": "A0A8V1AFE4", "url": "https://omabrowser.org/oma/group/A0A8V1AFE4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "D3ZQH5-1", "protein_name": "Myotubularin related protein 11", "gene_name": "Mtmr11", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MWWGGRGQSFNIAPQKEEPELGFSGPKSDPGNRMPEPSSHQLGSCLASGCLPGEHILAWAPGRRKGPGLELPGTLICTNFRVTFQPCGWQRNQDTPLSSEYDFALINIGRLEAVSGLSRVQLLRPGSQLKFIPEEVLIHGRDFRLLRIGFEAGGLAPQAFQVTMAIIQARAQSSQVQQYRGITLSKAGKVSGSRKPPIPLLETLEDWETERKKQGARGWRVSMVNERFDVATSLSGYFWVPNRILDSEVRRAFAHFHQGRGPRLSWHHPGGSDLLRCAGFYIASDPNKEDIRAVELMLQAGHSDVVLVDTMDEMPSLADVQLAHLKLRALCLPDSSVAEDKWLSALEGTRWLDYVRSCLRKASDISVLVTSRVRSVVLQERGDRDFNGLLSSLVQLLLAPEARTLFGFQSLVQREWVAAGHPFLTRLGETGASEEAPVLPLFLDCAWQLLQQFPAEFEFSEFFLLALHDSIRVPDTLTFLRNTPWERGKKSGQFNSYTQVYTPEYSQPLAGSPANLHLSVWDWDLRYSKEQISQFLNPGYDPEHCPDSGLPRQQPSLMVPGSPSSMWLFSRGALTPLNQLCPWQDSTSLLTVSSHWLPRPARSSESLADQEWGLPSHWGACPLPPGLLLPGYLGPQIRFWKRCYLRGRPEVQIGSSALTISGLQDELSHLQELLRKWTPRISPEDHSKKRDPNTILSQIC", "length": 700 }, "evidence": [ { "id": "A0A8V1AFE4", "url": "https://omabrowser.org/oma/group/A0A8V1AFE4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E7F7E6-1", "protein_name": "Myotubularin-related protein 11", "gene_name": "mtmr11", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLTGSKTTFKVRQMVPDMKERMMSHSSLHARGRDVLGLCCLPGECVLQRAVLVRKKLSAKEGGGWLSGTLFCTHFRVAFVPQDSQKPDDNADPVLLGDHDVALASIEKVVAVGPSRTKLVTPTCSLKFTPEELVLYCRDLRVLCFLFDRLTPDTQAVEITYTIAKTYQPLKPGTILSFQNAALGSIEMKQFLSNRRRDPSMNWLECSLGWEQELERTGASGWRVSSVNDRFEMSTSLPRFNVVPQRVLDTELKKTFAHFNEGRIPRWCWRHPRGSDLLRMASFQNNIYHEKDDIRNLELVLFGGQQLCVIVDLGEEMPSPADIQLAHTRLRTLCLGDISSSVSVPDDKWLSTLESTRWLDYTRCCLRKAAEVCCLLRAGHMTVVLQEPEDRDMNCVVCSLVQVMCDPHCRTVAGFQGLVQKEWITAGHKFLSRINYHRESDKEEAPVFLLFLDCVWQLWAQYPARFQLTEDYLLALHDSVHLPLFSSFLANSQRERCRRSQHLPQSYTPVNGLRDVPMSVPEEPVDPPFPPVWDWALQYSSQRRARFTQPISQPTCPPPVLNGNLNTNLERSWHNDGLPGSVFLLSRSTFSHPSNLLPWRSSNSGSYWKSHRRAPSSESLSGLERLIRACSLSEPSENNTILHDPYEPLLPLLLGPCVRVWRSCYLRGALHAQAFSHPVSSCTQHPVDQLAWEVQQLREKLAQASNRRPENQIKHQEARRPESNLNQNANNGTFLFSSSRVSQQQQQQAPSSRGAAQSSAPPRPQRTASDPPRPAQRNSGKHTFLFGHQQEPQSGQRYIPSPSAKLHKRPGNSQ", "length": 814 }, "evidence": [ { "id": "A0A8V1AFE4", "url": "https://omabrowser.org/oma/group/A0A8V1AFE4/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1MWR0-1", "protein_name": "Myotubularin related protein 11", "gene_name": "MTMR11", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MWWGGRGQSFNIAPQKEEPEMGLSGPKSVQGTGMPEPRSRQLGSCLASGGLPGEQILAWAPGVRKGLEPEMPGTLICSNLRVTFQPHGWQRSQETPLSSEYDFSLANIGRLEAVHGPSRVQLLRPGSLLKFIPEEILIHGQDFRLLRVGFEAGGLEPQAFQVTMAIVQARAQNSPAQQYAGITLSQAGQSSDSRKPPIPLLETIEDWETERKKQAARGWRVSTVNERFDVATSLPRYFWVPNRTLDSEVRRAFGHFHQGRGPRLSWHHPGGSDLLRCGGFYTASDPNKEDIRAVESMLQAGHSDVVLVDTMDELPSLADVQLAHLRLRALCLPDSSVAEDKWFSALEGTRWLDYTRSCLRKASDISVLVTSRVRSVVLQERGDRDFNGLLSSLVQLLSAPEARTLLGFQSLVQREWVAAGHPFLTRLGGSGASEEAPVFLLFLDCVWQLLQQFPAEFEFSEFFLLALHDSVRVPDTLTFLRDTPWERGKQSGQFNNYTQVYTPGFPGAGNSINPQLSVWDWNLRYSNKQILQFRNPGYDPEHCPDSWLPRQQPSFMVPGPPSSVWLFSRGSLTPLNQLCPWRDSPSLLAVSSRWLPRPAISSESLADQEWGLPSHWGACPLPPGLLLPGCLGPQIRLWRRCYLRGRPEVQMGLSAPTISGLQEELSHLQELLRKWTPRISPEDHSKRRNPNTILSQSR", "length": 698 }, "evidence": [ { "id": "A0A8V1AFE4", "url": "https://omabrowser.org/oma/group/A0A8V1AFE4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1SDG2-1", "protein_name": "Myotubularin related protein 11", "gene_name": "MTMR11", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MWWGGRGQSFNIAPQKEEPEMGLSGPKSVQGRAMPEPRSRQLGSCLASGCLPGEQILAWAPGVRKGLEPELPGTLICSNLRVTFQPCGWQRSQETPLSSEYDFSLANIGRLEAVNGLSRVQLLRPGSLLKFVPEEILIHGRDFRLLRIGFEAGGLEPQAFQVTMAIVQARAQSSQGQKYAGLTLSKAGQSAGSRKPPIPLLEISEDWETERRKQRARGWRVSTVNERFDIATSLPRYFWVPNRTLDSEVRRAFGHFHQGRGPRLTWHHPGGSDLLRCGGFYTASDPNKEDIRAVETMLQAGHSDVVLVDTLDELPSLADVQLAHLRLRALCLPDSSVAEDKWLSALEGTRWLDYVRSCLRKASDISVLVTSRVRSVVLQERCDRDFNGLLSSLVQLLSSPEARTLLGFQSLVQREWVAAGHPFLTRLGGTGASEEAPVFLLFLDCVWQLLQQFPAEFEFSEFFLLALHDSVRVPDTLTFLRDSPWERGKQSGQINTYTQVYTAGYSQPPAGNSINPQLSVWDWDLRYSNEQILQFHNPGYDPEHCPDSWLPRQQPSFMVPGPPTSVWLFSRGALTPLNQLCPWRDSPSLLAVSSRWLPRPASSSESLADQEWGLPSHWGACPLPSGLLLPGYLGPQIRLWRRCYLRGRPEVQMGLSAPTIAGLQDELSHLQELLRKWTPRISPEDHSKKRDPNTILSQSH", "length": 700 }, "evidence": [ { "id": "A0A8V1AFE4", "url": "https://omabrowser.org/oma/group/A0A8V1AFE4/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q3V1L6-1", "protein_name": "Myotubularin-related protein 11", "gene_name": "Mtmr11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWWGGRGQSFNIAPQKEEPEMGLSGPKSNPGNRMPEPSSHQLGSCLASGCLPGEHILAWAPGRRKGPGLDLPGTLICTNFRVTFQPCGWQRKQDTPLSSENDFALINIGRLEAVSGLSRVQLLRPGSQLKFIPEELLLHGRDFRLLRVGFEAGGLAPQAFQVTMAIIQARAQSSQVQQYRGITLSKVGKVSGSRKPPIPLLETLEDWETECKKQGARGWRVSTVNERFDVATSLSGYFWVPNRILDSEVRRAFAHFHQGRGPRLSWHHPGGSDLLRCGGFYIASDPNKEDIRAVESMLQAGHSDVVLVETMDEMPSLADIQLAHLKLRALCLPDSSVAEDKWLSALEGTRWLDYVRSCLRKASDISVLVTSRVRSVVLQELGDRDFNGLLSSLVQLLLAPEARTLFGFQSLVQREWVAAGHPFLTRLGDTGASEEAPVFPLFLDCAWQLLQQFPAEFEFSEFFLLALHDSIRVPDTLTFLRNTPWERGKKSGQFNSYTQVYTPEYSQPLAGSSANLHLSVWDWDLRYSKEQISQFLNPGYDPEHCPDSRFSRQQQSLMVPGPPSSMWLFSRGTLTPLNQLCPWQDSSSLLAVSSHWLPRPARSSESLADQEWGLPSHWGACPLPPGLLLPGYLGPQIRFWKRCYLRGRPEVQMGSSALTVSALQDELSHLQELLRQWTPRISPEDQSKKRDPNTILSQIC", "length": 700 }, "evidence": [ { "id": "A0A8V1AFE4", "url": "https://omabrowser.org/oma/group/A0A8V1AFE4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFE4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFE4" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFE4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFE4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 236, "end_pos": 238, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AFE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFE4" }, { "id": "PS51339", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51339" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Myotubularin phosphatase", "eco_id": "ECO_0000259", "start_pos": 167, "end_pos": 603, "start_aa": "Phe", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 236, "end_pos": 238 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AFE7-1", "uniprot_ac": "A0A8V1AFE7", "uniprot_id": "A0A8V1AFE7_CHICK", "mass": { "chemical_mass": 36882.0, "monoisotopic_mass": 36882.0 }, "refseq": { "ac": "XP_003642913", "name": "leucine-rich alpha-2-glycoprotein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642913" }, "gene_names": [ { "name": "LRG1", "type": "recommended", "evidence": [ { "id": "A0A8V1AFE7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFE7" } ] }, { "name": "LRG1", "type": "synonym", "evidence": [ { "id": "XP_003642913", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642913" } ] } ], "protein_names": [ { "name": "Leucine rich alpha-2-glycoprotein 1", "type": "synonym", "evidence": [ { "id": "A0A8V1AFE7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFE7/entry#names_and_taxonomy" } ] }, { "name": "leucine-rich alpha-2-glycoprotein", "type": "synonym", "evidence": [ { "id": "XP_003642913", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642913" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 100% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052559.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_003642913.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003642913", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642913" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFE7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFE7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LRG1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFE7", "locus": {} } ], "crossref": [ { "id": "A0A8V1AFE7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AFE7", "database": "AlphaFoldDB", "categories": [] }, { "id": "100858066", "url": "https://www.ncbi.nlm.nih.gov/gene/100858066", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000483", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000483", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003591", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003591", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050467", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050467", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:100858066", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100858066", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CDQNLSD", "url": "https://omabrowser.org/oma/group/CDQNLSD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AFE7", "url": "https://www.orthodb.org/?gene=A0A8V1AFE7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45842", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45842", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45842:SF12", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45842:SF12", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00560", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00560", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13516", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13516", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13855", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13855", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003642913", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642913", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AFE7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFE7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFE7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFE7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MALLGHILPPPPPLPLLLLLLPYSHAAPCHPQPNATHFICTEPTLSTFPSGLPPTTVAISVEFTAMTTISPNALAGLPRLQELHLSSNHLAVLPEALLQPVPTLRTLDLTDNLLPDLPAGIFHPSIHLRHLVLQGNLLQALQPSWFVHLTQLHWLNLAGNALLEVPPAALRPLRSLRSLDLAHNHLQHLSADTFVGLQMLERLDLEGNQLRALPPTLFAPTPSLRLLFLQNNTLQVLPDGIFSPLLHLRVLDLAHNHLQALQLPPRSPPGPPLSLDMSGNPWACDCSLLALLQDAAPQLIAARATRCASPAQHRGQEVTAVSQAGDEGCQHGGDKQSPLDH", "length": 341, "header": "tr|A0A8V1AFE7-1|A0A8V1AFE7_CHICK Isoform 1 of Leucine rich alpha-2-glycoprotein 1 OS=Gallus gallus OX=9031 GN=LRG1 PE=4 SV=1 CANONICAL=A0A8V1AFE7-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AFE7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFE7/entry#A0A8V1AFE7-1", "sequence": { "sequence": "MALLGHILPPPPPLPLLLLLLPYSHAAPCHPQPNATHFICTEPTLSTFPSGLPPTTVAISVEFTAMTTISPNALAGLPRLQELHLSSNHLAVLPEALLQPVPTLRTLDLTDNLLPDLPAGIFHPSIHLRHLVLQGNLLQALQPSWFVHLTQLHWLNLAGNALLEVPPAALRPLRSLRSLDLAHNHLQHLSADTFVGLQMLERLDLEGNQLRALPPTLFAPTPSLRLLFLQNNTLQVLPDGIFSPLLHLRVLDLAHNHLQALQLPPRSPPGPPLSLDMSGNPWACDCSLLALLQDAAPQLIAARATRCASPAQHRGQEVTAVSQAGDEGCQHGGDKQSPLDH", "length": 341, "header": "tr|A0A8V1AFE7-1|A0A8V1AFE7_CHICK Isoform 1 of Leucine rich alpha-2-glycoprotein 1 OS=Gallus gallus OX=9031 GN=LRG1 PE=4 SV=1 CANONICAL=A0A8V1AFE7-1" }, "locus": { "chromosome": "28", "start_pos": 2983636, "end_pos": 2982614, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065981.1", "url": "https://www.ensembl.org/id/ENSGALT00010065981.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040247.1", "url": "https://www.ensembl.org/id/ENSGALP00010040247.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 221, "start_aa": "Thr", "end_pos": 221, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr221", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:100858066", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100858066", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F6RMV5-1", "protein_name": "Leucine rich alpha-2-glycoprotein 1", "gene_name": "LRG1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MKKREATMSSQNPERKQSLVGWDSHLSRIFLLLLFVVSAQGLTPNPEACLVFSSVNGSSISCQPPAQIPHSLPADTIFLAVEFFNLTQLPADFLQGVPNLQELHLSSNRLEDFSPKFLLPVPQLKVLDLTRNSLTGLFPGFFRVSAALCTLVLKGNQLKFLEASWLHGLKALRHLDLSENQLHSLPPGLLENFTDLLTLDLSNNQLQTLPPDLLRGPLNLERLHLEGNRLQVLGEGLLAPQPKLRYLFLNDNRLASVAAGAFRGLQKLDMLDLSNNLLTTVPTGLWTSLGKAARNLKDGFDISNNPWICDQNLADLYRWLVANENKMFFRNHTRCAGPEALKGQTLLAAAESH", "length": 353 }, "evidence": [ { "id": "A0A8V1AFE7", "url": "https://omabrowser.org/oma/group/A0A8V1AFE7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "M0R8H5-1", "protein_name": "Leucine-rich alpha-2-glycoprotein 1", "gene_name": "Lrg1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "TLFLLALLGGVSGLRECLILQSVKGSTVSCHGPTEFPSSLPADTVHLSVEFSSLTQLPAAALQGCPGLQELHLSSNRLQELSPGLLAPVPRLRVLDLTRNALRSLPPGLFRSSAALNTLVLRENQLQEASARWLQGLDALGYLDLAENRLRSLPARLLANLGALHTLDLGHNLLESLPEGFLRGPRRLQRLHLEGNRLQRLEAGLLAPQPFLGVLFLNDNQLTAVAADSFRGLKQLDMLDLSNNSLSSTPPGLWAFLGRPTRDMQDGFDVSHNPWVCDKDLVDLCRWLAANRHKMFSQNDTLCAGPEAVRGQRLLDVAELGTL", "length": 323 }, "evidence": [ { "id": "A0A8V1AFE7", "url": "https://omabrowser.org/oma/group/A0A8V1AFE7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P02750-1", "protein_name": "Leucine-rich alpha-2-glycoprotein", "gene_name": "LRG1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSSWSRQRPKSPGGIQPHVSRTLFLLLLLAASAWGVTLSPKDCQVFRSDHGSSISCQPPAEIPGYLPADTVHLAVEFFNLTHLPANLLQGASKLQELHLSSNGLESLSPEFLRPVPQLRVLDLTRNALTGLPPGLFQASATLDTLVLKENQLEVLEVSWLHGLKALGHLDLSGNRLRKLPPGLLANFTLLRTLDLGENQLETLPPDLLRGPLQLERLHLEGNKLQVLGKDLLLPQPDLRYLFLNGNKLARVAAGAFQGLRQLDMLDLSNNSLASVPEGLWASLGQPNWDMRDGFDISGNPWICDQNLSDLYRWLQAQKDKMFSQNDTRCAGPEAVKGQTLLAVAKSQ", "length": 347 }, "evidence": [ { "id": "A0A8V1AFE7", "url": "https://omabrowser.org/oma/group/A0A8V1AFE7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5RHE5-1", "protein_name": "Leucine-rich alpha-2-glycoprotein precursor", "gene_name": "si:dkey-90m5.4", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNSWLVRALAVMLVLCSRDALSCPKRCTCHFSAKTTEVVCPDAGLSHFPGDGLPPSTTSLTIQFTNLTVLTSEHLRAVPLLEELHLPGNKLSSLPADILKDLKYLHTIDLTDNELRELPEYVFRHAPLLNLVLKDNRISNIHPDWFPNNSNLTWLDLSGNQLMKFPMAQLQNLRHLKVLHLSQNKIEELPVGCLDAHTALERLYLDQNKIQTLDVKAFSGSTNLTHIFLQKNRIDSLPPTVFQELKRLEYVDLSDNRLQFLSPGILDINTSWVELTFNPWHCDAKIEYLWRKITMESLQSEPKCAAPENLKDRVIATLTRKDMGLKE", "length": 327 }, "evidence": [ { "id": "A0A8V1AFE7", "url": "https://omabrowser.org/oma/group/A0A8V1AFE7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 231, "end_pos": 233, "annotation": "n_glycosylation_sequon" }, { "start_pos": 34, "end_pos": 36, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AFE7", "database": "UniProtKB", "url": 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"sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AFF4-1", "uniprot_ac": "A0A8V1AFF4", "uniprot_id": "A0A8V1AFF4_CHICK", "mass": { "chemical_mass": 20364.0, "monoisotopic_mass": 20364.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Keratin", "type": "recommended", "evidence": [ { "id": "A0A8V1AFF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFF4/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFF4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFF4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFF4", "locus": {} } ], "crossref": [ { "id": "A0A8V1AFF4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AFF4", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR003461", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003461", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR31203", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31203", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31203:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31203:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02422", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02422", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1AFF4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFF4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFF4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFF4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHM3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHM3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHM3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHM3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJU7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJU7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJU7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJU7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALM3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALM3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALM3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALM3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MIKPAQCHVLPIALQVDLPSGKMSYGQMISFRCAQPCEVSCPQPYTDSRNEPCVATCGDSRAIVYAPPVVVTFPGPIISSCPQESIVGTAIPEIEGGGMGSGGGGMGSGGGGIGSGGSYGGGSSYGGGSSYGGGGSCGIGSHSSGGSYGGVGGGSYGGEGSCGGGFSRLGGYYRSSFYSGFGRNYFPFYSRYYRYRYGNCGPF", "length": 203, "header": "tr|A0A8V1AFF4-1|A0A8V1AFF4_CHICK Isoform 1 of Keratin OS=Gallus gallus OX=9031 GN= PE=3 SV=1 CANONICAL=A0A8V1AFF4-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AFF4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFF4/entry#A0A8V1AFF4-1", "sequence": { "sequence": "MIKPAQCHVLPIALQVDLPSGKMSYGQMISFRCAQPCEVSCPQPYTDSRNEPCVATCGDSRAIVYAPPVVVTFPGPIISSCPQESIVGTAIPEIEGGGMGSGGGGMGSGGGGIGSGGSYGGGSSYGGGSSYGGGGSCGIGSHSSGGSYGGVGGGSYGGEGSCGGGFSRLGGYYRSSFYSGFGRNYFPFYSRYYRYRYGNCGPF", "length": 203, "header": "tr|A0A8V1AFF4-1|A0A8V1AFF4_CHICK Isoform 1 of Keratin OS=Gallus gallus OX=9031 GN= PE=3 SV=1 CANONICAL=A0A8V1AFF4-1" }, "locus": { "chromosome": "25", "start_pos": 1355700, "end_pos": 1352916, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069583.1", "url": "https://www.ensembl.org/id/ENSGALT00010069583.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042844.1", "url": "https://www.ensembl.org/id/ENSGALP00010042844.1" } ] } }, { "isoform_ac": "A0A8V1AHM3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFF4/entry#A0A8V1AHM3-1", "sequence": { "sequence": "MSYGQMISFRCAQPCEVSCPQPYTDSRNEPCVATCGDSRAIVYAPPVVVTFPGPIISSCPQESIVGTAIPEIEGGGMGSGGGGMGSGGGGIGSGGSYGGGSSYGGSCGIGSHSSGGSYGGVGGGSYGGEGSCGGGFSRLGGYYRSSFYSGFGRNYFPFYSRYYRYRYGNCGPF", "length": 173, "header": "tr|A0A8V1AHM3-1|A0A8V1AFF4_CHICK Computationally mapped isoform of Keratin OS=Gallus gallus OX=9031 GN= PE=3 SV=1 CANONICAL=A0A8V1AFF4-1" }, "locus": { "chromosome": "25", "start_pos": 1355700, "end_pos": 1355116, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069585.1", "url": "https://www.ensembl.org/id/ENSGALT00010069585.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042846.1", "url": "https://www.ensembl.org/id/ENSGALP00010042846.1" } ] } }, { "isoform_ac": "A0A8V1AJU7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFF4/entry#A0A8V1AJU7-1", "sequence": { "sequence": "MSYGQMISFRCAQPCEVSCPQPYTDSRNEPCVATCGDSRAIVYAPPVVVTFPGPIISSSYGGGGSCGIGSHSSGGSYGGVGGGSYGGEGSCGGGFSRLGGYYRSSFYSGFGRNYFPFYSRYYRYRYGNCGPF", "length": 132, "header": "tr|A0A8V1AJU7-1|A0A8V1AFF4_CHICK Computationally mapped isoform of Keratin OS=Gallus gallus OX=9031 GN= PE=3 SV=1 CANONICAL=A0A8V1AFF4-1" }, "locus": { "chromosome": "25", "start_pos": 1355700, "end_pos": 1355116, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069584.1", "url": "https://www.ensembl.org/id/ENSGALT00010069584.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042845.1", "url": "https://www.ensembl.org/id/ENSGALP00010042845.1" } ] } }, { "isoform_ac": "A0A8V1ALM3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFF4/entry#A0A8V1ALM3-1", "sequence": { "sequence": "MSYGQMISFRCAQPCEVSCPQPYTDSRNEPCVATCGDSRAIVYAPPVVVTFPGPIISSCPQESIVGTAIPEIEGGGMGSGGGGMGSGGGGMGSGGGGMGSGGGGIGSGGSYGGGSSYGGGSSYGGGGSCGIGSHSSGGSYGGVGGGSYGGEGSCGGGFSRLGGYYRSSFYSGFGRNYFPFYSRYYRYRYGNCGPF", "length": 195, "header": "tr|A0A8V1ALM3-1|A0A8V1AFF4_CHICK Computationally mapped isoform of Keratin OS=Gallus gallus OX=9031 GN= PE=3 SV=1 CANONICAL=A0A8V1AFF4-1" }, "locus": { "chromosome": "25", "start_pos": 1355700, "end_pos": 1355116, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069582.1", "url": "https://www.ensembl.org/id/ENSGALT00010069582.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042843.1", "url": "https://www.ensembl.org/id/ENSGALP00010042843.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "structural constituent of cytoskeleton", "id": "GO:0005200", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005200", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFF4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFF4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "intermediate filament", "id": "GO:0005882", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005882", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFF4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFF4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AFG1-1", "uniprot_ac": "A0A8V1AFG1", "uniprot_id": "A0A8V1AFG1_CHICK", "mass": { "chemical_mass": 40114.0, "monoisotopic_mass": 40114.0 }, "refseq": { "ac": "XP_415631", "name": "SAP30-binding protein isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_415631" }, "gene_names": [ { "name": "SAP30BP", "type": "recommended", "evidence": [ { "id": "A0A8V1AFG1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFG1" } ] }, { "name": "SAP30BP", "type": "synonym", "evidence": [ { "id": "XP_415631", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_415631" } ] } ], "protein_names": [ { "name": "SAP30 binding protein", "type": "synonym", "evidence": [ { "id": "A0A8V1AFG1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFG1/entry#names_and_taxonomy" } ] }, { "name": "SAP30-binding protein isoform X1", "type": "synonym", "evidence": [ { "id": "XP_415631", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_415631" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052549.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_415631.3. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_415631", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_415631" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFG1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFG1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SAP30BP", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFG1", "locus": { "chromosome": "18", "start_pos": 5372714, "end_pos": 5402642, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029812", "url": "https://www.ensembl.org/id/ENSGALG00010029812" } ] } } ], "crossref": [ { "id": "A0A8V1AFG1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AFG1", "database": "AlphaFoldDB", "categories": [] }, { "id": "417375", "url": "https://www.ncbi.nlm.nih.gov/gene/417375", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR012479", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012479", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:417375", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417375", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "XSFSERV", "url": "https://omabrowser.org/oma/group/XSFSERV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AFG1", "url": "https://www.orthodb.org/?gene=A0A8V1AFG1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AMC0", "url": "https://www.orthodb.org/?gene=A0A8V1AMC0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AQ76", "url": "https://www.orthodb.org/?gene=A0A8V1AQ76", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13464", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13464", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13464:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13464:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07818", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07818", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_415631", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_415631", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AFG1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFG1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFG1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFG1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AMC0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMC0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AMC0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMC0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AQ76", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AQ76", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AQ76-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AQ76-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSSLSVLSAWQCASINVSPVDQRPFKAEGGGRRCYGDCSDVISARRKRSRLWQKMAAAKRSVLSSLAVYAEDSDPESDSETGTAGSDGGTATGEKGGLVSVGYGEDDFSRLDGDEEGYEEDDDENSRQSEDDDSETEKPEAGDLKEFSELEKRDPQELVASFSERVRNMSPDEIRIPPEPPGRCSNHLQDKIQKLYERKIKEGMDMNYIIQRKKEFRNPSIYEKLIQFCSIDELGTNYPKDMFDPHGWSEDSYYEALAKAQKIEMDKLEKAKKERTKIEFVTGTKKGTTTSAASTTTTTASTTVGDAQKRKSKWDSAIPVTTIAQPTILTTTATLPGVVTVTTSASGSKTTVISAVGTIVKKAKQ", "length": 365, "header": "tr|A0A8V1AFG1-1|A0A8V1AFG1_CHICK Isoform 1 of SAP30 binding protein OS=Gallus gallus OX=9031 GN=SAP30BP PE=4 SV=1 CANONICAL=A0A8V1AFG1-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AFG1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFG1/entry#A0A8V1AFG1-1", "sequence": { "sequence": "MSSLSVLSAWQCASINVSPVDQRPFKAEGGGRRCYGDCSDVISARRKRSRLWQKMAAAKRSVLSSLAVYAEDSDPESDSETGTAGSDGGTATGEKGGLVSVGYGEDDFSRLDGDEEGYEEDDDENSRQSEDDDSETEKPEAGDLKEFSELEKRDPQELVASFSERVRNMSPDEIRIPPEPPGRCSNHLQDKIQKLYERKIKEGMDMNYIIQRKKEFRNPSIYEKLIQFCSIDELGTNYPKDMFDPHGWSEDSYYEALAKAQKIEMDKLEKAKKERTKIEFVTGTKKGTTTSAASTTTTTASTTVGDAQKRKSKWDSAIPVTTIAQPTILTTTATLPGVVTVTTSASGSKTTVISAVGTIVKKAKQ", "length": 365, "header": "tr|A0A8V1AFG1-1|A0A8V1AFG1_CHICK Isoform 1 of SAP30 binding protein OS=Gallus gallus OX=9031 GN=SAP30BP PE=4 SV=1 CANONICAL=A0A8V1AFG1-1" }, "locus": { "chromosome": "18", "start_pos": 5402443, "end_pos": 5373688, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010072125.1", "url": "https://www.ensembl.org/id/ENSGALT00010072125.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044761.1", "url": "https://www.ensembl.org/id/ENSGALP00010044761.1" } ] } }, { "isoform_ac": "A0A8V1AMC0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFG1/entry#A0A8V1AMC0-1", "sequence": { "sequence": "MAAAKRSVLSSLAVYAEDSDPESDSETGTAGSDGGTATGEKGGLVSVGYGEDDFSRLDGDEEGYEEDDDENSRQSEDDDSETEKPEAGDLKEFSELEKRDPQELVASFSERVRNMSPDEIRIPPEPPGRCSNHLQDKIQKLYERKIKEGMDMNYIIQRKKEFRNPRTCLILMAGQRTHIMRH", "length": 182, "header": "tr|A0A8V1AMC0-1|A0A8V1AFG1_CHICK Computationally mapped isoform of SAP30 binding protein OS=Gallus gallus OX=9031 GN=SAP30BP PE=4 SV=1 CANONICAL=A0A8V1AFG1-1" }, "locus": { "chromosome": "18", "start_pos": 5402281, "end_pos": 5376195, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010072124.1", "url": "https://www.ensembl.org/id/ENSGALT00010072124.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044760.1", "url": "https://www.ensembl.org/id/ENSGALP00010044760.1" } ] } }, { "isoform_ac": "A0A8V1AQ76-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFG1/entry#A0A8V1AQ76-1", "sequence": { "sequence": "MSSLSVLSAWQCASINVSPVDQRPFKAEGGGRRCYGDCSDVISARRKRSRLWQKMAAAKRSVLSSLAVYAEDSDPESDSETGTAGSDGGTATGEKGGLVSVGYGEDDFSRLDGDEEGYEEDDDENSRQSEFSELEKRDPQELVASFSERVRNMSPDEIRIPPEPPGRCSNHLQDKIQKLYERKIKEGMDMNYIIQRKKEFRNPSIYEKLIQFCSIDELGTNYPKDMFDPHGWSEDSYYEALAKAQKIEMDKLEKAKKERTKIEFVTGTKKGTTTSAASTTTTTASTTVGDAQKRKSKWDSAIPVTTIAQPTILTTTATLPGVVTVTTSASGSKTTVISAVGTIVKKAKQ", "length": 349, "header": "tr|A0A8V1AQ76-1|A0A8V1AFG1_CHICK Computationally mapped isoform of SAP30 binding protein OS=Gallus gallus OX=9031 GN=SAP30BP PE=4 SV=1 CANONICAL=A0A8V1AFG1-1" }, "locus": { "chromosome": "18", "start_pos": 5402443, "end_pos": 5373688, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010072127.1", "url": "https://www.ensembl.org/id/ENSGALT00010072127.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044762.1", "url": "https://www.ensembl.org/id/ENSGALP00010044762.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:417375", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417375", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1LZK2-1", "protein_name": "SAP30 binding protein", "gene_name": "SAP30BP", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAGKKNVLSSLAVYDEDSEAESDGEAGVETAGSAADEKGGLVSKAYGDDDFSRLAGDEDGYEEEEDENSKPSEDDDSETEKPEADDPKDNPEVEKRDPQELVASFSERVRNMSPDEIKIPPEPPGRCSNHLQDKIQKLYERKIKEGMDMNYIIQRKKEFRNPSIYEKLIQFCAIDELGTNYPKDMFDPHGWSEDSYYEALAKAQKIEMDKLEKAKKERTKIEFVTGTKKGTTTNATATTTTTASTAVADAQKRKSKWDSAIPVTTIAQPTILTTTATLPAVVTVTTSASGSKTTVISAVGTIVKKAKQ", "length": 308 }, "evidence": [ { "id": "A0A8V1AFG1", "url": "https://omabrowser.org/oma/group/A0A8V1AFG1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A481C7C1-1", "protein_name": "SAP30 binding protein", "gene_name": "SAP30BP", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAGKKNVLSSLAVYAEDSEPESDGEAGVETAGSAAEEKGGLVSEAYGEDDFSRLGGDEDGYEEEEDENSKQSEDDDSETEKPEADDPKDNPEAEKRDPQELVASFSERVRNMSPDEIKIPPEPPGRCSNHLQDKIQKLYERKIKEGMDMNYIIQRKKEFRNPSIYEKLIQFCAIDELGTNYPKDMFDPHGWSEDSYYEALAKAQKIEMDKLEKAKKERTKIEFVTGTKKGTTTNATATTTTTASTAVADAQKRKSKWDSAIPVTTIAQPTILTTTATLPAVVTVTTSASGSKTTVISAVGTIVKKAKQ", "length": 308 }, "evidence": [ { "id": "A0A8V1AFG1", "url": "https://omabrowser.org/oma/group/A0A8V1AFG1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8I5ZZ81-1", "protein_name": "SAP30 binding protein", "gene_name": "Sap30bp", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGKKNVLSSLAVYAEYSDPESDGETGVDAVGSAAEEKGGLVSDAYGEDDFSRPGGDEDGYEEEEDENSKQSEDDDSETEKPEADDPKVFESPLFSTASFSEKVRNMSPDEIKIPPEPPGRCSNHLQDKIQKLYERKIKEGMDMNYIIQRKKEFRNPSSCALWCRSDYSLTSSLQDMFDPHGWSEDSYYEALAQEMDTCLCNGLIVLSPLQIEFVTGTKKGTTTNATATTTSTASTAVADAQKRKSKWDSAIPVTTIAQPTILTTTATLPAVVTVTTSASGSKTTVISAVGTIVKKAKQ", "length": 299 }, "evidence": [ { "id": "A0A8V1AFG1", "url": "https://omabrowser.org/oma/group/A0A8V1AFG1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1QJR8-1", "protein_name": "SAP30-binding protein", "gene_name": "sap30bp", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MASSKKSALISSLAAYGDDSEQDSDPDTDDQESRGLVSASYGEDEVSRVEEAYEKPSENEDSDEDSTRNSDEEESDSGRIQDDVKEVQEVEVKDPNELVAQFSEKVRNMSPDEIRIPPEPPGRCSSHLQEKIFKLYERKLQGDFDTNSHIQKKKEFRNPSIYEKLIQFCDIDELGTNYPKDMFDPHGWSEDSYYEALAKAQKVEMDKLEKAKKEKTKIEFVTGTKKGTTTNAAALATNTTATSSTDAQKRKSKWDSAVPVTLAQPALLTTTATLPGVVSVTTTASGTKTTVISAVGTIHKKAKQ", "length": 304 }, "evidence": [ { "id": "A0A8V1AFG1", "url": "https://omabrowser.org/oma/group/A0A8V1AFG1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q9UHR5-1", "protein_name": "SAP30-binding protein", "gene_name": "SAP30BP", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAGKKNVLSSLAVYAEDSEPESDGEAGIEAVGSAAEEKGGLVSDAYGEDDFSRLGGDEDGYEEEEDENSRQSEDDDSETEKPEADDPKDNTEAEKRDPQELVASFSERVRNMSPDEIKIPPEPPGRCSNHLQDKIQKLYERKIKEGMDMNYIIQRKKEFRNPSIYEKLIQFCAIDELGTNYPKDMFDPHGWSEDSYYEALAKAQKIEMDKLEKAKKERTKIEFVTGTKKGTTTNATSTTTTTASTAVADAQKRKSKWDSAIPVTTIAQPTILTTTATLPAVVTVTTSASGSKTTVISAVGTIVKKAKQ", "length": 308 }, "evidence": [ { "id": "A0A8V1AFG1", "url": "https://omabrowser.org/oma/group/A0A8V1AFG1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFG1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFG1" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFG1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFG1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFG1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFG1" } ], "pmid": "" }, { "name": "response to virus", "id": "GO:0009615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009615", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFG1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFG1" } ], "pmid": "" }, { "name": "regulation of mRNA splicing, via spliceosome", "id": "GO:0048024", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048024", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFG1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFG1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "cyclin-dependent protein serine/threonine kinase regulator activity", "id": "GO:0016538", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016538", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFG1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFG1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 168, "end_pos": 170, "annotation": "n_glycosylation_sequon" }, { "start_pos": 16, "end_pos": 18, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 168, "end_pos": 170 }, { "start_pos": 16, "end_pos": 18 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AFI8-1", "uniprot_ac": "A0A8V1AFI8", "uniprot_id": "A0A8V1AFI8_CHICK", "mass": { "chemical_mass": 65526.0, "monoisotopic_mass": 65526.0 }, "refseq": {}, "gene_names": [ { "name": "PEX11G", "type": "recommended", "evidence": [ { "id": "A0A8V1AFI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFI8" } ] } ], "protein_names": [ { "name": "Peroxisomal biosis factor 11 gamma", "type": "synonym", "evidence": [ { "id": "A0A8V1AFI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFI8/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFI8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFI8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PEX11G", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFI8", "locus": { "chromosome": "28", "start_pos": 4514412, "end_pos": 4505857, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027236", "url": "https://www.ensembl.org/id/ENSGALG00010027236" } ] } } ], "crossref": [ { "id": "cd18464", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18464", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006652", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006652", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011705", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011705", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015915", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015915", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017096", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017096", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:425795", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:425795", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CGTQRCK", "url": "https://omabrowser.org/oma/group/CGTQRCK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AFI8", "url": "https://www.orthodb.org/?gene=A0A8V1AFI8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24412", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24412", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24412:SF502", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24412:SF502", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00651", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00651", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01344", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01344", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07707", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07707", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24681", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24681", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1AFI8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFI8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFI8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFI8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSVSSHENRKSRSSSGSMNIHLFHKPGHADSLLTHLNLLRKRHLFTDAVLRAGNRTFHCHRAVLAACSRYFDAMFSGGLKESRDAEVNFHDSLHPEVLELLLDYAYSARVLINEENAESLLEAGDMLQFQDVRDASADFLEKNLYPGNCLNMLLLSDAHCCERLLELSWRMALANFTSLCKTEDFLRLPKDKLLELVESEELEVEDESLVYEAVMGWIRYDLPRRHEVLPELLRSVRLALLPESYLRNEVACEKLVVSHKLGEEIVADAVRCKMRILQNDGVVTGCCARPRKVSQALLLLGGQTFVCDKIYTLDQKTREIIPRADIPSPRKECSACAVGCKVYITGGKGSENGASRDVWVYDTLHDEWAKAAPMLVARFGHGSAELDHCLYVVGGHTAVSGAFPASPSVSLKQVEHYDPQLDKWSLVAPLREGVSNAAVVGARMKLFVFGGTSANQEKLPKVQCFDPRQNRWTVPGSCPQPWRYTAAAVVGSHVIVIGGDTEFSASSAYRFHSDTFQWSKFGDVTAKRISCRAVTSGNRLYVVGGYCGAQRCKTLDCYDPSSDTWSSVTTVPYSLIPTAFVSTWKYLAA", "length": 589, "header": "tr|A0A8V1AFI8-1|A0A8V1AFI8_CHICK Isoform 1 of Peroxisomal biosis factor 11 gamma OS=Gallus gallus OX=9031 GN=PEX11G PE=4 SV=1 CANONICAL=A0A8V1AFI8-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AFI8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFI8/entry#A0A8V1AFI8-1", "sequence": { "sequence": "MSVSSHENRKSRSSSGSMNIHLFHKPGHADSLLTHLNLLRKRHLFTDAVLRAGNRTFHCHRAVLAACSRYFDAMFSGGLKESRDAEVNFHDSLHPEVLELLLDYAYSARVLINEENAESLLEAGDMLQFQDVRDASADFLEKNLYPGNCLNMLLLSDAHCCERLLELSWRMALANFTSLCKTEDFLRLPKDKLLELVESEELEVEDESLVYEAVMGWIRYDLPRRHEVLPELLRSVRLALLPESYLRNEVACEKLVVSHKLGEEIVADAVRCKMRILQNDGVVTGCCARPRKVSQALLLLGGQTFVCDKIYTLDQKTREIIPRADIPSPRKECSACAVGCKVYITGGKGSENGASRDVWVYDTLHDEWAKAAPMLVARFGHGSAELDHCLYVVGGHTAVSGAFPASPSVSLKQVEHYDPQLDKWSLVAPLREGVSNAAVVGARMKLFVFGGTSANQEKLPKVQCFDPRQNRWTVPGSCPQPWRYTAAAVVGSHVIVIGGDTEFSASSAYRFHSDTFQWSKFGDVTAKRISCRAVTSGNRLYVVGGYCGAQRCKTLDCYDPSSDTWSSVTTVPYSLIPTAFVSTWKYLAA", "length": 589, "header": "tr|A0A8V1AFI8-1|A0A8V1AFI8_CHICK Isoform 1 of Peroxisomal biosis factor 11 gamma OS=Gallus gallus OX=9031 GN=PEX11G PE=4 SV=1 CANONICAL=A0A8V1AFI8-1" }, "locus": { "chromosome": "28", "start_pos": 4511644, "end_pos": 4509878, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066036.1", "url": "https://www.ensembl.org/id/ENSGALT00010066036.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040302.1", "url": "https://www.ensembl.org/id/ENSGALP00010040302.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 535, "start_aa": "Thr", "end_pos": 535, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr535", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:425795", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:425795", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "ubiquitin-dependent protein catabolic process", "id": "GO:0006511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006511", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFI8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFI8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "ubiquitin-like ligase-substrate adaptor activity", "id": "GO:1990756", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990756", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFI8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFI8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "Cul3-RING ubiquitin ligase complex", "id": "GO:0031463", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031463", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFI8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFI8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 175, "end_pos": 177, "annotation": "n_glycosylation_sequon" }, { "start_pos": 54, "end_pos": 56, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AFI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFI8" }, { "id": "PS50097", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50097" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BTB", "eco_id": "ECO_0000259", "start_pos": 46, "end_pos": 114, "start_aa": "Thr", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 535 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 175, "end_pos": 177 }, { "start_pos": 54, "end_pos": 56 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AFJ1-1", "uniprot_ac": "A0A8V1AFJ1", "uniprot_id": "A0A8V1AFJ1_CHICK", "mass": { "chemical_mass": 75090.0, "monoisotopic_mass": 75090.0 }, "refseq": {}, "gene_names": [ { "name": "ZNF212", "type": "recommended", "evidence": [ { "id": "A0A8V1AFJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFJ1" } ] } ], "protein_names": [ { "name": "Zinc finger protein 212", "type": "synonym", "evidence": [ { "id": "A0A8V1AFJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFJ1/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFJ1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ZNF212", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFJ1", "locus": {} } ], "crossref": [ { "id": "A0A8V1AFJ1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AFJ1", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd07765", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07765", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001909", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001909", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036051", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036051", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050636", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050636", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AFJ1", "url": "https://www.orthodb.org/?gene=A0A8V1AFJ1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47772", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47772", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47772:SF14", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47772:SF14", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01352", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01352", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12874", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12874", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-212436", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-212436", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1AFJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFJ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFJ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFJ1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSCPGLAEASSWSTRTRRARAAQAAGQGEAQAQQLRELWSRTEKAERRLLAFENLVAELGSNLAALGNLLQDYGHLQQRLDNVENLLKNRNFWILRLPPGTRGEVPKVPITFDDIAVYFNEQEWERLDSWQKDLYKAVMRDYAVSKPDILSRIERGEELCVKDCWEPPQTLNRDGPESPRTIQDGQELTQTHNTGSEEPLQAHIQDNEEPIQDCSKDSEELLKTCLKDGQEPTQTCITDSQDTPQTGIEDRQEPLQAPEEMDQMEEALGKDVRVEADMEFAVSNPDIPSQTETNEELSVQDSQEPPKLCIQDSQEAPQTLKKMDQKKEPLGKDEVAVKGGTKFPRVVMHVLSVSAQKEKLSREEHPDSEVEDDPADFGSEEVLLLENDKASEAASLPESVKVKEEGPMASQEASAPSPDSQVQKRPEGEQAKPKSKKKPSRYASNGLLMGDCRRGYVREWSHPCTECGKRFRLKINLIIHQRSHAKEGPYECTICEISFTDKKRLVLHQGIHMQERAFAAKVWGNTHPELRMGPRRKLCRSPHGSAQSLAYRTRPGGSWLGQAREELSRPYFSQQPMPSTQTRSVVKCNLCNKSLSCPSSLQRHLKTHAKDRPYCCSTCKKCFTRQTHLVRHEQIHERQKALQNQQPKAEQPLSAAATPSWPQL", "length": 664, "header": "tr|A0A8V1AFJ1-1|A0A8V1AFJ1_CHICK Isoform 1 of Zinc finger protein 212 OS=Gallus gallus OX=9031 GN=ZNF212 PE=4 SV=1 CANONICAL=A0A8V1AFJ1-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AFJ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFJ1/entry#A0A8V1AFJ1-1", "sequence": { "sequence": "MSCPGLAEASSWSTRTRRARAAQAAGQGEAQAQQLRELWSRTEKAERRLLAFENLVAELGSNLAALGNLLQDYGHLQQRLDNVENLLKNRNFWILRLPPGTRGEVPKVPITFDDIAVYFNEQEWERLDSWQKDLYKAVMRDYAVSKPDILSRIERGEELCVKDCWEPPQTLNRDGPESPRTIQDGQELTQTHNTGSEEPLQAHIQDNEEPIQDCSKDSEELLKTCLKDGQEPTQTCITDSQDTPQTGIEDRQEPLQAPEEMDQMEEALGKDVRVEADMEFAVSNPDIPSQTETNEELSVQDSQEPPKLCIQDSQEAPQTLKKMDQKKEPLGKDEVAVKGGTKFPRVVMHVLSVSAQKEKLSREEHPDSEVEDDPADFGSEEVLLLENDKASEAASLPESVKVKEEGPMASQEASAPSPDSQVQKRPEGEQAKPKSKKKPSRYASNGLLMGDCRRGYVREWSHPCTECGKRFRLKINLIIHQRSHAKEGPYECTICEISFTDKKRLVLHQGIHMQERAFAAKVWGNTHPELRMGPRRKLCRSPHGSAQSLAYRTRPGGSWLGQAREELSRPYFSQQPMPSTQTRSVVKCNLCNKSLSCPSSLQRHLKTHAKDRPYCCSTCKKCFTRQTHLVRHEQIHERQKALQNQQPKAEQPLSAAATPSWPQL", "length": 664, "header": "tr|A0A8V1AFJ1-1|A0A8V1AFJ1_CHICK Isoform 1 of Zinc finger protein 212 OS=Gallus gallus OX=9031 GN=ZNF212 PE=4 SV=1 CANONICAL=A0A8V1AFJ1-1" }, "locus": { "chromosome": "2", "start_pos": 541009, "end_pos": 534525, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066038.1", "url": "https://www.ensembl.org/id/ENSGALT00010066038.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040304.1", "url": "https://www.ensembl.org/id/ENSGALP00010040304.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 658, "start_aa": "Thr", "end_pos": 658, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr658", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-GGA-212436", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-212436", "resource": "Reactome", "description": "Generic Transcription Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFJ1" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFJ1" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFJ1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFJ1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFJ1" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFJ1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 592, "end_pos": 594, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AFJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFJ1" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 462, "end_pos": 489, "start_aa": "His", "end_aa": "Pro", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1AFJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFJ1" }, { "id": "PS50805", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50805" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "KRAB", "eco_id": "ECO_0000259", "start_pos": 110, "end_pos": 172, "start_aa": "Ile", "end_aa": "Asn", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 658 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 592, "end_pos": 594 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AFJ7-1", "uniprot_ac": "A0A8V1AFJ7", "uniprot_id": "A0A8V1AFJ7_CHICK", "mass": { "chemical_mass": 313717.0, "monoisotopic_mass": 313717.0 }, "refseq": {}, "gene_names": [ { "name": "SETX", "type": "recommended", "evidence": [ { "id": "A0A8V1AFJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFJ7" } ] } ], "protein_names": [ { "name": "Senataxin", "type": "synonym", "evidence": [ { "id": "A0A8V1AFJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFJ7/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFJ7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SETX", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFJ7", "locus": { "chromosome": "17", "start_pos": 7095305, "end_pos": 7123946, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028771", "url": "https://www.ensembl.org/id/ENSGALG00010028771" } ] } } ], "crossref": [ { "id": "cd18042", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18042", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18808", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18808", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041679", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041679", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045055", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045055", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047187", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047187", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AFJ7", "url": "https://www.orthodb.org/?gene=A0A8V1AFJ7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AJX7", "url": "https://www.orthodb.org/?gene=A0A8V1AJX7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ALQ3", "url": "https://www.orthodb.org/?gene=A0A8V1ALQ3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10887", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10887", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10887:SF537", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10887:SF537", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13086", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13086", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13087", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13087", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1AFJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFJ7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFJ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFJ7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJX7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJX7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJX7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJX7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALQ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALQ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALQ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALQ3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNVCRWCTPSGLDATEYLKSYASKQLSPEDLEGSNDDLCYCLECVVEYHKAREKLPSLHQVLLELETSRLVAHIEKSIREEAGEDDELFIVDENGETQLPVYVGPDFENNLRVPLLEVLKYPYLLLHEKVSELCVEVLCRMEENHTSFQVFEKYPGIYLFLVHPNEVIRRWAILTARNLGKVDRDDYYDLQEVLTCLFKVIELGLFESPDIYRSSVIEKGKLILLPSHLYDNSNYKNYWLGICMLLTVLEEQAMDSLLLGPDKQNDFMQSILHTMEKEADDDSTDPFWPALHCFMVILDQLGSKVWGQLIDPVQAFQTIINSVSYNSEIKNIRNNFVRTKSELKTDYDDEMVTCSQIVYTCNTEKPQKDTGWKTAICPDYCPNMYEDMQTLANVLQSDIGGDMRVHHSTFLWFIPFVQSLMDLKDLGVAYIVEVIHYLCSEIKDILNERIQRCDKVSEFFLLILVSIIELHRNKKCLHLLWISSQEWVEAVVRCAKLPAIAFTRCTEKVAGSNARGSSTISLQAFNSVQHACVQLIRSLLKEGYQIGQHALCKQYLDKLNLLLRGNLSLGWQLNIQETQELQTCLKQVIRNLKSRALNASVSVENNANSTALPTVSLKQEKSAPGSGYKTSVHGRENLCSPVAFISKEGEDGCCQEISFTGRNSAWEEDCKDSSKNSKSLTSTDCLLVNIKKEPKDLITQECESLQKSFAKEMYGKVLENRNNDLMSGNCAMGNQGFSTSIQSSNFRRSGVLENKQETEAVSPAYLSAQTCVDSPEHVCSSDVKGRNASAGSSSEFKDGHRLGHLHFQTHSAEGHSRPLPQIADLKNCSSATSASEAEQLVFCTGSSCMRKDCGKHQGVNTVGENEDRESAGISRSSESTWEKSAFQYGLVSKNQEQKEMPLDCFSFAKSQPGLQGNKDNSILLADTSDTLLQNVSTKDDSSLLLKSVCLKDQEQPNLGDLDKCDRKGQISKTSCTVKKSVSDHIPSGSENKGVMSNTALPVGPLAVKCEPSERLIVCSKYFMRENNAEGKEEEDFVRMVSGHNTSTNSQIDKELSKLSLAAYAKSVNFPSESSQESSMHHNICDVKRKVKSAVRSSNSAQSNQSLCDTDSHGNKIIIILDSSDEENGVTVNEETKELNENMCPEKQPVSEMQHDVTGSTLESKMPNSPLPLEDCDSQYFEFETEIDVFSVWQDTQEYKQDCVSASIDSHSDGLSQDHTNEWGYDTDYISDGAMEEETKWTREEINTSHQKETDNTEVTNSTLQEFSTKENAKDEVEISTDGSTVDKDFILNAELTEPRASTSSVSLASKLAFKKSTLSPRKNTTKSKVARSIQRSPKATALSATQTKKLFQSTLKRIQPGRTTPAVVPPKKARQCPAPTSTVEKLGLKKAPRKAFELSQRSLDSLAQLRSYGKVAGKVGVAQRGKVKRTAHPSLSTQINKKMLACQDLQFLKQTRLSKSVRVKNTPRCSEDRSKKVNTMDTKSVKQKAKCSDQPSVEKQREKQTGETFYPSVNERGHVTSISAENEAAQTTFVSDCSGSNKAKDCDVMVPPVPMDSSLCSDATVGDDKGKPEGGCTVQPESGVTPSKENECKPDENSDDDDNLFLTQLDPVDMELCSQDEDAEGNTIATTRTEEMEIDRAESLQQNDTLTVVKCKYKDCTEKVKKIGDCCSRHLATNSESDHLFAKPSSLPPRKPSTTKIFSSVSSSRNAAFSKDLENVEKQPPALKSRASIAKPAVLRPRSEKAIPTRKQTCRTPSSSNIPQPYISNNVLQSRNNTQINNASNISRWPVQAERCSSFLGAQQHDHNIFVKEVLKWTYEMFANSIQFGPPSTLVQSVVASVPIRFQGYNDYFNTFFPLMMLNAFETLAQEWVENQKMKDKTYYLHLQNFCADLNTAEFIGYFEETDLTKQLHPKEDDLIFLVGQKKKNVFGEDREVEDHLVNHVGLVRRFSRASGCLTRQKDQHTVCHLSVQTRGNLSFFVNNEVKCMVVGSLVPTQRSFKGLLLLSRSPLAKPIINPSYSDFCPRDLPVSSESATFCMNEYNEDQKRAIETAYAMVKQHPGLAKICLIHGPPGTGKSKTIVGLLSRVLRENTRNEKTSKKNAKIKQNRFLVCAPSNAAIDELMKKIIIAFKEKCQNRQEPLGNCGDIKLVRLGAERSINSEVRAFSLDKQVEHRMKRKPTDRDQDIQKKKAALDEKLDMLSRQRAMHRCEKRESQMLDDEIGRLSKERQQLASQLKEVRGHSQKVQTDIILESDIICCTLSTSGGGLLESAFWRQGLDPFSCVIVDEAGQSCEVETLIPLIHRCNKLVLVGDPRQLPPTIKSIKAQEYGYGQSLMARLQRHLEEQVQNNLLRRLPVVQLTVQYRMHPDICLFPSSYIYDKTLKTDKATEENRCSSEWPFQPYLVFDVGDGREERDKDSFSNPQEVKLVLEIIRTIKEKRKDLGLRRIGIITPYSAQKKKIQEELDRVFKNNSPGEVDTVDAFQGREKDCIIVTCVRANSSKGSIGFLASLQRLNVTITRARFSLFILGRLKTLMENKDWNKLIQDAQRRGAIIKTSDKSYKKDALKILKLKPPPQNPPCQLPTKAGTTKAPLAEACSSSRKMGEPADPSEASRPREVAAGPSHAAPQGSRMPQLPQGAQVADSRRASISAPAEAAALPADKEKPRDPRLARMASRTETKRKEQTPKDSSQSAQSTRESMLQQRLDVSSAARDRIARTEPSKKHHQTKGQHDTPSTLPYGAKVEHDRRAPLPEHHSKASSERGQCSSSKWNRDTLTLVRTSKSSSVSTDSNSAKRRKTSH", "length": 2801, "header": "tr|A0A8V1AFJ7-1|A0A8V1AFJ7_CHICK Isoform 1 of Senataxin OS=Gallus gallus OX=9031 GN=SETX PE=4 SV=1 CANONICAL=A0A8V1AFJ7-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AFJ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFJ7/entry#A0A8V1AFJ7-1", "sequence": { "sequence": "MNVCRWCTPSGLDATEYLKSYASKQLSPEDLEGSNDDLCYCLECVVEYHKAREKLPSLHQVLLELETSRLVAHIEKSIREEAGEDDELFIVDENGETQLPVYVGPDFENNLRVPLLEVLKYPYLLLHEKVSELCVEVLCRMEENHTSFQVFEKYPGIYLFLVHPNEVIRRWAILTARNLGKVDRDDYYDLQEVLTCLFKVIELGLFESPDIYRSSVIEKGKLILLPSHLYDNSNYKNYWLGICMLLTVLEEQAMDSLLLGPDKQNDFMQSILHTMEKEADDDSTDPFWPALHCFMVILDQLGSKVWGQLIDPVQAFQTIINSVSYNSEIKNIRNNFVRTKSELKTDYDDEMVTCSQIVYTCNTEKPQKDTGWKTAICPDYCPNMYEDMQTLANVLQSDIGGDMRVHHSTFLWFIPFVQSLMDLKDLGVAYIVEVIHYLCSEIKDILNERIQRCDKVSEFFLLILVSIIELHRNKKCLHLLWISSQEWVEAVVRCAKLPAIAFTRCTEKVAGSNARGSSTISLQAFNSVQHACVQLIRSLLKEGYQIGQHALCKQYLDKLNLLLRGNLSLGWQLNIQETQELQTCLKQVIRNLKSRALNASVSVENNANSTALPTVSLKQEKSAPGSGYKTSVHGRENLCSPVAFISKEGEDGCCQEISFTGRNSAWEEDCKDSSKNSKSLTSTDCLLVNIKKEPKDLITQECESLQKSFAKEMYGKVLENRNNDLMSGNCAMGNQGFSTSIQSSNFRRSGVLENKQETEAVSPAYLSAQTCVDSPEHVCSSDVKGRNASAGSSSEFKDGHRLGHLHFQTHSAEGHSRPLPQIADLKNCSSATSASEAEQLVFCTGSSCMRKDCGKHQGVNTVGENEDRESAGISRSSESTWEKSAFQYGLVSKNQEQKEMPLDCFSFAKSQPGLQGNKDNSILLADTSDTLLQNVSTKDDSSLLLKSVCLKDQEQPNLGDLDKCDRKGQISKTSCTVKKSVSDHIPSGSENKGVMSNTALPVGPLAVKCEPSERLIVCSKYFMRENNAEGKEEEDFVRMVSGHNTSTNSQIDKELSKLSLAAYAKSVNFPSESSQESSMHHNICDVKRKVKSAVRSSNSAQSNQSLCDTDSHGNKIIIILDSSDEENGVTVNEETKELNENMCPEKQPVSEMQHDVTGSTLESKMPNSPLPLEDCDSQYFEFETEIDVFSVWQDTQEYKQDCVSASIDSHSDGLSQDHTNEWGYDTDYISDGAMEEETKWTREEINTSHQKETDNTEVTNSTLQEFSTKENAKDEVEISTDGSTVDKDFILNAELTEPRASTSSVSLASKLAFKKSTLSPRKNTTKSKVARSIQRSPKATALSATQTKKLFQSTLKRIQPGRTTPAVVPPKKARQCPAPTSTVEKLGLKKAPRKAFELSQRSLDSLAQLRSYGKVAGKVGVAQRGKVKRTAHPSLSTQINKKMLACQDLQFLKQTRLSKSVRVKNTPRCSEDRSKKVNTMDTKSVKQKAKCSDQPSVEKQREKQTGETFYPSVNERGHVTSISAENEAAQTTFVSDCSGSNKAKDCDVMVPPVPMDSSLCSDATVGDDKGKPEGGCTVQPESGVTPSKENECKPDENSDDDDNLFLTQLDPVDMELCSQDEDAEGNTIATTRTEEMEIDRAESLQQNDTLTVVKCKYKDCTEKVKKIGDCCSRHLATNSESDHLFAKPSSLPPRKPSTTKIFSSVSSSRNAAFSKDLENVEKQPPALKSRASIAKPAVLRPRSEKAIPTRKQTCRTPSSSNIPQPYISNNVLQSRNNTQINNASNISRWPVQAERCSSFLGAQQHDHNIFVKEVLKWTYEMFANSIQFGPPSTLVQSVVASVPIRFQGYNDYFNTFFPLMMLNAFETLAQEWVENQKMKDKTYYLHLQNFCADLNTAEFIGYFEETDLTKQLHPKEDDLIFLVGQKKKNVFGEDREVEDHLVNHVGLVRRFSRASGCLTRQKDQHTVCHLSVQTRGNLSFFVNNEVKCMVVGSLVPTQRSFKGLLLLSRSPLAKPIINPSYSDFCPRDLPVSSESATFCMNEYNEDQKRAIETAYAMVKQHPGLAKICLIHGPPGTGKSKTIVGLLSRVLRENTRNEKTSKKNAKIKQNRFLVCAPSNAAIDELMKKIIIAFKEKCQNRQEPLGNCGDIKLVRLGAERSINSEVRAFSLDKQVEHRMKRKPTDRDQDIQKKKAALDEKLDMLSRQRAMHRCEKRESQMLDDEIGRLSKERQQLASQLKEVRGHSQKVQTDIILESDIICCTLSTSGGGLLESAFWRQGLDPFSCVIVDEAGQSCEVETLIPLIHRCNKLVLVGDPRQLPPTIKSIKAQEYGYGQSLMARLQRHLEEQVQNNLLRRLPVVQLTVQYRMHPDICLFPSSYIYDKTLKTDKATEENRCSSEWPFQPYLVFDVGDGREERDKDSFSNPQEVKLVLEIIRTIKEKRKDLGLRRIGIITPYSAQKKKIQEELDRVFKNNSPGEVDTVDAFQGREKDCIIVTCVRANSSKGSIGFLASLQRLNVTITRARFSLFILGRLKTLMENKDWNKLIQDAQRRGAIIKTSDKSYKKDALKILKLKPPPQNPPCQLPTKAGTTKAPLAEACSSSRKMGEPADPSEASRPREVAAGPSHAAPQGSRMPQLPQGAQVADSRRASISAPAEAAALPADKEKPRDPRLARMASRTETKRKEQTPKDSSQSAQSTRESMLQQRLDVSSAARDRIARTEPSKKHHQTKGQHDTPSTLPYGAKVEHDRRAPLPEHHSKASSERGQCSSSKWNRDTLTLVRTSKSSSVSTDSNSAKRRKTSH", "length": 2801, "header": "tr|A0A8V1AFJ7-1|A0A8V1AFJ7_CHICK Isoform 1 of Senataxin OS=Gallus gallus OX=9031 GN=SETX PE=4 SV=1 CANONICAL=A0A8V1AFJ7-1" }, "locus": { "chromosome": "17", "start_pos": 7121383, "end_pos": 7096309, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069623.1", "url": "https://www.ensembl.org/id/ENSGALT00010069623.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042884.1", "url": "https://www.ensembl.org/id/ENSGALP00010042884.1" } ] } }, { "isoform_ac": "A0A8V1AJX7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFJ7/entry#A0A8V1AJX7-1", "sequence": { "sequence": "MNVCRWCTPSGLDATEYLKSYASKQLSPEDLEGSNDDLCYCLECVVEYHKAREKLPSLHQVLLELETSRLVAHIEKSIREEAGEDDELFIVDENGETQLPVYVGPDFENNLRVPLLEVLKYPYLLLHEKVSELCVEVLCRMEENHTSFQVFEKYPGIYLFLVHPNEVIRRWAILTARNLGKVDRDDYYDLQEVLTCLFKVIELGLFESPDIYRSSVIEKGKLILLPSHLYDNSNYKNYWLGICMLLTVLEEQAMDSLLLGPDKQNDFMQSILHTMEKEADDDSTDPFWPALHCFMVILDQLGSKVWGQLIDPVQAFQTIINSVSYNSEIKNIRNNFVRTKSELKTDYDDEMVTCSQIVYTCNTEKPQKDTGWKTAICPDYCPNMYEDMQTLANVLQSDIGGDMRVHHSTFLWFIPFVQSLMDLKDLGVAYIVEVIHYLCSEIKDILNERIQRCDKVSEFFLLILVSIIELHRNKKCLHLLWISSQEWVEAVVRCAKLPAIAFTRCTEKVAGSNARGSSTISLQAFNSVQHACVQLIRSLLKEGYQIGQHALCKQYLDKLNLLLRGNLSLGWQLNIQETQELQTCLKQVIRNLKSRALNASVSVENNANSTALPTVSLKQEKSAPGSGYKTSVHGRENLCSPVAFISKEGEDGCCQEISFTGRNSAWEEDCKDSSKNSKSLTSTDCLLVNIKKEPKDLITQECESLQKSFAKEMYGKVLENRNNDLMSGNCAMGNQGFSTSIQSSNFRRSGVLENKQETEAVSPAYLSAQTCVDSPEHVCSSDVKGRNASAGSSSEFKDGHRLGHLHFQTHSAEGHSRPLPQIADLKNCSSATSASEAEQLVFCTGSSCMRKDCGKHQGVNTVGENEDRESAGISRSSESTWEKSAFQYGLVSKNQEQKEMPLDCFSFAKSQPGLQGNKDNSILLADTSDTLLQNVSTKDDSSLLLKSVCLKDQEQPNLGDLDKCDRKGQISKTSCTVKKSVSDHIPSGSENKGVMSNTALPVGPLAVKCEPSERLIVCSKYFMRENNAEGKEEEDFVRMVSGHNTSTNSQIDKELSKLSLAAYAKSVNFPSESSQESSMHHNICDVKRKVKSAVRSSNSAQSNQSLCDTDSHGNKIIIILDSSDEENGVTVNEETKELNENMCPEKQPVSEMQHDVTGSTLESKMPNSPLPLEDCDSQYFEFETEIDVFSVWQDTQEYKQDCVSASIDSHSDGLSQDHTNEWGYDTDYISDGAMEEETKWTREEINTSHQKETDNTEVTNSTLQEFSTKENAKDEVEISTDGSTVDKDFILNAELTEPRASTSSVSLASKLAFKKSTLSPRKNTTKSKVARSIQRSPKATALSATQTKKLFQSTLKRIQPGRTTPAVVPPKKARQCPAPTSTVEKLGLKKAPRKAFELSQRSLDSLAQLRSYGKVAGKVGVAQRGKVKRTAHPSLSTQINKKMLACQDLQFLKQTRLSKSVRVKNTPRCSEDRSKKVNTMDTKSVKQKAKCSDQPSVEKQREKQTGETFYPSVNERGHVTSISAENEAAQTTFVSDCSGSNKAKDCDVMVPPVPMDSSLCSDATVGDDKGKPEGGCTVQPESGVTPSKENECKPDENSDDDDNLFLTQLDPVDMELCSQDEDAEGNTIATTRTEEMEIDRAESLQQNDTLTVVKCKYKDCTEKVKKIGDCCSRHLATNSESDHLFAKPSSLPPRKPSTTKIFSSVSSSRNAAFSKDLENVEKQPPALKSRASIAKPAVLRPRSEKAIPTRKQTCRTPSSSNIPQPYISNNVLQSRNNTQINNASNISRWPVQAERCSSFLGAQQHDHNIFVKEVLKWTYEMFANSIQFGPPSTLVQSVVASVPIRFQGYNDYFNTFFPLMMLNAFETLAQEWVENQKMKDKTYYLHLQNFCADLNTAEFIGYFEETDLTKQLHPKEDDLIFLVGQKKKNVFGEDREVEDHLVNHVGLVRRFSRASGCLTRQKDQHTVCHLSVQTRGNLSFFVNNEVKCMVVGSLVPTQRSFKGLLLLSRSPLAKPIINPSYSDFCPRDLPVSSESATFCMNEYNEDQKRAIETAYAMVKQHPGLAKICLIHGPPGTGKSKTIVGLLSRVLRENTRNEKTSKKNAKIKQNRFLVCAPSNAAIDELMKKIIIAFKEKCQNRQEPLGNCGDIKLVRLGAERSINSEVRAFSLDKQVEHRMKRKPTDRDQDIQKKKAALDEKLDMLSRQRAMHRCEKRESQMLDDEIGRLSKERQQLASQLKEVRGHSQKVQTDIILESDIICCTLSTSGGGLLESAFWRQGLDPFSCVIVDEAGQSCEVETLIPLIHRCNKLVLVGDPRQLPPTIKSIKAQEYGYGQSLMARLQRHLEEQVQNNLLRRLPVVQLTVQYRMHPDICLFPSSYIYDKTLKTDKATEENRCSSEWPFQPYLVFDVGDGREERDKDSFSNPQEVKLVLEIIRTIKEKRKDLGLRRIGIITPYSAQKKKIQEELDRVFKNNRFLASLQRLNVTITRARFSLFILGRLKTLMENKDWNKLIQDAQRRGAIIKTSDKSYKKDALKILKLKPPPQNPPCQLPTKAGTTKAPLAEACSSSRKMGEPADPSEASRPREVAAGPSHAAPQGSRMPQLPQGAQVADSRRASISAPAEAAALPADKEKPRDPRLARMASRTETKRKEQTPKDSSQSAQSTRESMLQQRLDVSSAARDRIARTEPSKKHHQTKGQHDTPSTLPYGAKVEHDRRAPLPEHHSKASSERGQCSSSKWNRDTLTLVRTSKSSSVSTDSNSAKRRKTSH", "length": 2768, "header": "tr|A0A8V1AJX7-1|A0A8V1AFJ7_CHICK Computationally mapped isoform of Senataxin OS=Gallus gallus OX=9031 GN=SETX PE=4 SV=1 CANONICAL=A0A8V1AFJ7-1" }, "locus": { "chromosome": "17", "start_pos": 7121383, "end_pos": 7096309, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069624.1", "url": "https://www.ensembl.org/id/ENSGALT00010069624.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042885.1", "url": "https://www.ensembl.org/id/ENSGALP00010042885.1" } ] } }, { "isoform_ac": "A0A8V1ALQ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFJ7/entry#A0A8V1ALQ3-1", "sequence": { "sequence": "MNVCRWCTPSGLDATEYLKSYASKQLSPEDLEGSNDDLCYCLECVVEYHKAREKLPSLHQVLLELETSRLVAHIEKSIREEAGEDDELFIVDENGETQLPVYVGPDFENNLRVPLLEVLKYPYLLLHEKVSELCVEVLCRMEENHTSFQVFEKYPGIYLFLVHPNEVIRRWAILTARNLGKVDRDDYYDLQEVLTCLFKVIELGLFESPDIYRSSVIEKGKLILLPSHLYDNSNYKNYWLGICMLLTVLEEQAMDSLLLGPDKQNDFMQSILHTMEKEADDDSTDPFWPALHCFMVILDQLGSKVWGQLIDPVQAFQTIINSVSYNSEIKNIRNNFVRTKSELKTDYDDEMVTCSQIVYTCNTEKPQKDTGWKTAICPDYCPNMYEDMQTLANVLQSDIGGDMRVHHSTFLWFIPFVQSLMDLKDLGVAYIVEVIHYLCSEIKDILNERIQRCDKVSEFFLLILVSIIELHRNKKCLHLLWISSQEWVEAVVRCAKLPAIAFTRCTEKVAGSNARGSSTISLQAFNSVQHACVQLIRSLLKEGYQIGQHALCKQYLDKLNLLLRGNLSLGWQLNIQETQELQTCLKQVIRNLKSRALNASVSVENNANSTALPTVSLKQEKSAPGSGYKTSVHGRENLCSPVAFISKEGEDGCCQEISFTGRNSAWEEDCKDSSKNSKSLTSTDCLLVNIKKEPKDLITQECESLQKSFAKEMYGKVLENRNNDLMSGNCAMGNQGFSTSIQSSNFRRSGVLENKQETEAVSPAYLSAQTCVDSPEHVCSSDVKGRNASAGSSSEFKDGHRLGHLHFQTHSAEGHSRPLPQIADLKNCSSATSASEAEQLVFCTGSSCMRKDCGKHQGVNTVGENEDRESAGISRSSESTWEKSAFQYGLVSKNQEQKEMPLDCFSFAKSQPGLQGNKDNSILLADTSDTLLQNVSTKDDSSLLLKSVCLKDQEQPNLGDLDKCDRKGQISKTSCTVKKSVSDHIPSGSENKGVMSNTALPVGPLAVKCEPSERLIVCSKYFMRENNAEGKEEEDFVRMVSGHNTSTNSQIDKELSKLSLAAYAKSVNFPSESSQESSMHHNICDVKRKVKSAVRSSNSAQSNQSLCDTDSHGNKIIIILDSSDEENGVTVNEETKELNENMCPEKQPVSEMQHDVTGSTLESKMPNSPLPLEDCDSQYFEFETEIDVFSVWQDTQEYKQDCVSASIDSHSDGLSQDHTNEWGYDTDYISDGAMEEETKWTREEINTSHQKETDNTEVTNSTLQEFSTKENAKDEVEISTDGSTVDKDFILNAELTEPRASTSSVSLASKLAFKKSTLSPRKNTTKSKVARSIQRSPKATALSATQTKKLFQSTLKRIQPGRTTPAVVPPKKARQCPAPTSTVEKLGLKKAPRKAFELSQRSLDSLAQLRSYGKVAGKVGVAQRGKVKRTAHPSLSTQINKKMLACQDLQFLKQTRLSKSVRVKNTPRCSEDRSKKVNTMDTKSVKQKAKCSDQPSVEKQREKQTGETFYPSVNERGHVTSISAENEAAQTTFVSDCSGSNKAKDCDVMVPPVPMDSSLCSDATVGDDKGKPEGGCTVQPESGVTPSKENECKPDENSDDDDNLFLTQLDPVDMELCSQDEDAEGNTIATTRTEEMEIDRAESLQQNDTLTVVKCKYKDCTEKVKKIGDCCSRHLATNSESDHLFAKPSSLPPRKPSTTKIFSSVSSSRNAAFSKDLENVEKQPPALKSRASIAKPAVLRPRSEKAIPTRKQTCRTPSSSNIPQPYISNNVLQSRNNTQINNASNISRWPVQAERCSSFLGAQQHDHNIFVKEVLKWTYEMFANSIQFGPPSTLVQSVVASVPIRFQGYNDYFNTFFPLMMLNAFETLAQEWVENQKMKDKTYYLHLQNFCADLNTAEFIGYFEETDLTKQLHPKEDDLIFLVGQKKKNVFGEDREVEDHLVNHVGLVRRFSRASGCLTRQKDQHTVCHLSVQTRGNLSFFVNNEVKCMVVGSLVPTQRSFKGLLLLSRSPLAKPIINPSYSDFCPRDLPVSSESATFCMNEYNEDQKRAIETAYAMVKQHPGLAKICLIHGPPGTGKSKTIVGLLSRVLRENTRNEKTSKKNAKIKQNRFLVCAPSNAAIDELMKKIIIAFKEKCQNRQEPLGNCGDIKLVRLGAERSINSEVRAFSLDKQVEHRMKRKPTDRDQDIQKKKAALDEKLDMLSRQRAMHRCEKRESQMLDDEIGRLSKERQQLASQLKEVRGHSQKVQTDIILESDIICCTLSTSGGGLLESAFWRQGLDPFSCVIVDEKAQEYGYGQSLMARLQRHLEEQVQNNLLRRLPVVQLTVQYRMHPDICLFPSSYIYDKTLKTDKATEENRCSSEWPFQPYLVFDVGDGREERDKDSFSNPQEVKLVLEIIRTIKEKRKDLGLRRIGIITPYSAQKKKIQEELDRVFKNNSPGEVDTVDAFQGREKDCIIVTCVRANSSKGSIGFLASLQRLNVTITRARFSLFILGRLKTLMENKDWNKLIQDAQRRGAIIKTSDKSYKKDALKILKLKPPPQNPPCQLPTKAGTTKAPLAEACSSSRKMGEPADPSEASRPREVAAGPSHAAPQGSRMPQLPQGAQVADSRRASISAPAEAAALPADKEKPRDPRLARMASRTETKRKEQTPKDSSQSAQSTRESMLQQRLDVSSAARDRIARTEPSKKHHQTKGQHDTPSTLPYGAKVEHDRRAPLPEHHSKASSERGQCSSSKWNRDTLTLVRTSKSSSVSTDSNSAKRRKTSH", "length": 2765, "header": "tr|A0A8V1ALQ3-1|A0A8V1AFJ7_CHICK Computationally mapped isoform of Senataxin OS=Gallus gallus OX=9031 GN=SETX PE=4 SV=1 CANONICAL=A0A8V1AFJ7-1" }, "locus": { "chromosome": "17", "start_pos": 7121383, "end_pos": 7096309, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069622.1", "url": "https://www.ensembl.org/id/ENSGALT00010069622.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042883.1", "url": "https://www.ensembl.org/id/ENSGALP00010042883.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "DNA/RNA helicase activity", "id": "GO:0033677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033677", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFJ7" } ], "pmid": "" }, { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFJ7" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFJ7" } ], "pmid": "" }, { "name": "transcription termination site sequence-specific DNA binding", "id": "GO:0001147", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001147", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFJ7" } ], "pmid": "" }, { "name": "helicase activity", "id": "GO:0004386", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004386", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFJ7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 9, "go_terms": [ { "name": "positive regulation of RNA splicing", "id": "GO:0033120", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033120", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFJ7" } ], "pmid": "" }, { "name": "positive regulation of neuron projection development", "id": "GO:0010976", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010976", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFJ7" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFJ7" } ], "pmid": "" }, { "name": "double-strand break repair", "id": "GO:0006302", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006302", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFJ7" } ], "pmid": "" }, { "name": "cellular response to hydrogen peroxide", "id": "GO:0070301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070301", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFJ7" } ], "pmid": "" }, { "name": "mRNA splice site recognition", "id": "GO:0006376", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006376", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFJ7" } ], "pmid": "" }, { "name": "positive regulation of termination of RNA polymerase II transcription, poly(A)-coupled", "id": "GO:2000806", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000806", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFJ7" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription initiation", "id": "GO:2000144", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000144", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFJ7" } ], "pmid": "" }, { "name": "termination of RNA polymerase II transcription", "id": "GO:0006369", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006369", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFJ7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFJ7" } ], "pmid": "" }, { "name": "growth cone", "id": "GO:0030426", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030426", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFJ7" } ], "pmid": "" }, { "name": "nuclear body", "id": "GO:0016604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016604", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFJ7" } ], "pmid": "" }, { "name": "nuclear chromosome", "id": "GO:0000228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000228", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFJ7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1044, "end_pos": 1046, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1103, "end_pos": 1105, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1246, "end_pos": 1248, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1260, "end_pos": 1262, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1323, "end_pos": 1325, "annotation": 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"https://www.ncbi.nlm.nih.gov/protein/NP_001376227" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: HAEK01027140.1, SRR13267662.19644.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000308.1. On Dec 9, 2020 this sequence version replaced XP_025011831.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001376227", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376227" } ] }, { "annotation": "Involved in RNA polymerase III-mediated transcription. Integral, tightly associated component of the DNA-binding TFIIIC2 subcomplex that directly binds tRNA and virus-associated RNA promoters.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFN2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFN2#function" }, { "database": "UniProtKB", "id": "ARBA00057927", "url": "https://www.uniprot.org/uniprotkb/ARBA00057927#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFN2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFN2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "GTF3C5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFN2", "locus": { "chromosome": "17", "start_pos": 7396075, "end_pos": 7387383, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028829", "url": "https://www.ensembl.org/id/ENSGALG00010028829" } ] } } ], "crossref": [ { "id": "A0A8V1AFN2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AFN2", "database": "AlphaFoldDB", "categories": [] }, { "id": "417164", "url": "https://www.ncbi.nlm.nih.gov/gene/417164", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019136", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019136", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040454", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040454", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041499", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041499", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042536", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042536", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PPEYFVR", "url": "https://omabrowser.org/oma/group/PPEYFVR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AFN2", "url": "https://www.orthodb.org/?gene=A0A8V1AFN2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13230", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13230", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13230:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13230:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF09734", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09734", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17682", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17682", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-76061", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-76061", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-76066", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-76066", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001376227", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376227", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AFN2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFN2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFN2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFN2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAADGPRTERGSGVLELPSTPRLVCVEYPGLVRDVSAMLRTLGGEEGVSRIYADPGKRLELYFRPKDPYCHPVCANRFPASAMLLRVKRRSRRKRLGEQDVQFEMEIMGIVTTVYKFQGMSDFQYLAMHSGPDGKQTSMYDKVLMLKPEKEEFFNRELPLYIPPPIFSRLDTPVDYYYRPDVQHREGYNNPQVSAENLIGLSRARRPNNAIFVNFDDEVPTKPLDAAAQAWKKVCTNPVDRKVEEELRKLFEVRPVWSRNAVKANISVHPDKLKLLLPCLAYYMITGPWRSLWVRFGYDPRKHPEAKIYQVLDFRIRCGMKYGYTPNDMPVKAKRSTYNYSLPITVKKPVSHTVSVHDLKQGLGTPGASGAKKPASSRYKLKESVYIFREGALPPYRQMFYQLCDLNVESLQKIIHRNDGTESECTERDGWCLPKTSDDLRDSMSLMIKQIIRSTRPALFSSTTSSEDGKEQLAYESGEDEDDEEEEEEEFKPSDGSENEMETEILDYV", "length": 509, "header": "tr|A0A8V1AFN2-1|A0A8V1AFN2_CHICK Isoform 1 of General transcription factor 3C polypeptide 5 OS=Gallus gallus OX=9031 GN=GTF3C5 PE=3 SV=1 CANONICAL=A0A8V1AFN2-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AFN2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFN2/entry#A0A8V1AFN2-1", "sequence": { "sequence": "MAADGPRTERGSGVLELPSTPRLVCVEYPGLVRDVSAMLRTLGGEEGVSRIYADPGKRLELYFRPKDPYCHPVCANRFPASAMLLRVKRRSRRKRLGEQDVQFEMEIMGIVTTVYKFQGMSDFQYLAMHSGPDGKQTSMYDKVLMLKPEKEEFFNRELPLYIPPPIFSRLDTPVDYYYRPDVQHREGYNNPQVSAENLIGLSRARRPNNAIFVNFDDEVPTKPLDAAAQAWKKVCTNPVDRKVEEELRKLFEVRPVWSRNAVKANISVHPDKLKLLLPCLAYYMITGPWRSLWVRFGYDPRKHPEAKIYQVLDFRIRCGMKYGYTPNDMPVKAKRSTYNYSLPITVKKPVSHTVSVHDLKQGLGTPGASGAKKPASSRYKLKESVYIFREGALPPYRQMFYQLCDLNVESLQKIIHRNDGTESECTERDGWCLPKTSDDLRDSMSLMIKQIIRSTRPALFSSTTSSEDGKEQLAYESGEDEDDEEEEEEEFKPSDGSENEMETEILDYV", "length": 509, "header": "tr|A0A8V1AFN2-1|A0A8V1AFN2_CHICK Isoform 1 of General transcription factor 3C polypeptide 5 OS=Gallus gallus OX=9031 GN=GTF3C5 PE=3 SV=1 CANONICAL=A0A8V1AFN2-1" }, "locus": { "chromosome": "17", "start_pos": 7393683, "end_pos": 7387391, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069735.1", "url": "https://www.ensembl.org/id/ENSGALT00010069735.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042914.1", "url": "https://www.ensembl.org/id/ENSGALP00010042914.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-76061", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-76061", "resource": "Reactome", "description": "RNA Polymerase III Transcription Initiation From Type 1 Promoter" }, { "id": "R-GGA-76066", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-76066", "resource": "Reactome", "description": "RNA Polymerase III Transcription Initiation From Type 2 Promoter" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A9J7JMF5-1", "protein_name": "General transcription factor 3C polypeptide 5 isoform X5", "gene_name": "Gtf3c5", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAAVEPDAEPKAAIPVDLRRERRLVCVEYPGVVRNEDKMLQTLGGEEGVSRVRSWENSGTAGKEPGERAVSLIYTDPTKRLELYFRPKDPYCHPVCANRFSTSSMLLRIRKRTRRQRGALGAETHPQVTFDLEILGIISTIYKFQGMSDFQYLAVHTEAGGKHVSMYDRVLMRKPEKEEFFHQELPLYIPPPIFSRLDTPVDYFYRPETQHREGYHNPSISGENLIGLSRARRPHNAIFVNFEDPEVPLQPLEAAVTTWKKACTNPIDQKVEEELRKLFDVRPIWSRNAVKSNVSVHPDKLKILLPYMAYYMITGPWRSLWIRFGYDPRKHPDAKIYQVLDFRIRCGMKYGYGSRDMPVKAKRSTYNYSLPITVKKTSNQLVTMHDLKQGLGPSGTDGPRKLTYNKYKLKDSVYIFREGALPPYRQMFYQLCDLNVEELQKIVHRNDGTESVCTERDGWCLPKTTDHLRDTMSLMILQTIRSERPALFSDTGKTDRGKGQLMFESGEEGEEEEEEEDEEDFKPSDGSENEMETEILDYV", "length": 539 }, "evidence": [ { "id": "A0A8V1AFN2", "url": "https://omabrowser.org/oma/group/A0A8V1AFN2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "E7EZ29-1", "protein_name": "General transcription factor 3C polypeptide 5", "gene_name": "gtf3c5", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MHKRQTKMDSVITSEAVSSDTEARNTGESRDEAVVLGNTATLALSDTNLVCVEYPAVVNNVNRMLDSIGGEQGVSKTYADSTKRIELRFRPGDPFCHPAYGNRYSSTNLLLRVRRRTRKGNNAETQISMEIVGLIGTTYKFQGMADFQYLASHNNPEGNQVSLYDKIILRKPEKKEFYDNPVPLFIPPPIFSRLDMPVDYFYRPDVMHNKDTAFQSALMKDHIIAPNRARRPNNAIFVNFDDKTIPSEPLEAAVTTWRKLCVHPNDLKAEKKIKQLFEKRPIWSRNAVKANIDIHPEKMKHLLPFVAYYALTGPWRSLWVRFGYDPRKIPGAKIYQVLDFRIRYGMKHGFGVNDMPVKSKRSAYHYSRPTTFNRAVPLPASVTDIPQESTSSSGPVTAKYMLKESIYIFREGMLPPYRQMFYQLCDLDVEKIQNLIHKNDGKEEVCDERDGWCVPHTADELRNIISGMIQQYVKANRPGPSTQKPVKRRAKDVGSGEEDDEDEDDDDDEEYKPSDGSDNEMETEIADYM", "length": 529 }, "evidence": [ { "id": "A0A8V1AFN2", "url": "https://omabrowser.org/oma/group/A0A8V1AFN2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8R2T8-1", "protein_name": "General transcription factor 3C polypeptide 5", "gene_name": "Gtf3c5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAAEPDADPKAAIPVDLRRERRLVCVEYPGVVRNEAKMLQTLGGEESVSRIYTDPTKRLELYFRPKDPYCHPVCANRFSTSSLLLRIRKRTRRRRGVLGDEAHPQVTFNLEIIGIISTIYKFQGMSDFQYLAVHTEAGGKHVSMYDRVLMRKPEKEEFFHQELPLYIPPPIFSRLDTPVDYFYRPETQHREGYHNPTISGENLIGLSRARRPHNAIFVNFEDTEVPEQPLEAAVQTWKKACTNPIDQKVEEELRKLFDIRPVWSRNAVKSNVSVHPDKLKILLPYMAYYMITGPWRSLWIRFGYDPRKHPDAKIYQVLDFRIRCGMKYGYGSRDMPVKAKRSTYNYSLPITVKKTSNQPGTMHDLKQGLGPSGTDGPRKLTYNKYKLKDSVYIFREGALPPYRQMFYQLCDLNVEELQKIVHRNDGTETVCTERDGWCLPKTTDHLRDTMSLMILQTIRSERPALFSNTGKADRGKEQLMFESGEEEEEEEEEEEEEEEDFKPSDGSENEMETEILDYV", "length": 520 }, "evidence": [ { "id": "A0A8V1AFN2", "url": "https://omabrowser.org/oma/group/A0A8V1AFN2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VIZ2-1", "protein_name": "Lethal (2) 37Cd", "gene_name": "l(2)37Cd", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSRQLSFNPQKEYELIEYPGRVVNPDRMIATLGGIINVSKVLGDEVKRLALHFHPENPYNKPTFGDCTDKTGVLLSITVRRHKKDKQRPPEYFVRVLGHCSRSFTFETLCDFQYLPLWSTPKSDNANAAQELTYALDQLKPKNTTDLDYFKRRHSQLLALPELFTHVDTVYAGTYRIDPSEDGQHEVLGVQSKSSYDNQGVVSFNMVDSFPTQADSQNLKRLKVKYVSDEQLALVKKLFDDCPIWTRIALQYESGLTNDKLKCITPSLAFYFSNGPWRTLYVRFGYDPRKDFNSRYYQTFDFRLRFSTGLSEFVYAKKFVKQRRAANAPFAPIEDRVSDLVQDIDYPYFDEHKLPRSRQCMLRYCDVRMTRIQEMLEKIPTPLTGAVCNERTGWLPPGFDAQVRQIVCASISELLRNHYRKENLTAEVEAVTQADEEDEDEAEDEETQEEDMELDETQAMGNSEQFVDNDIEQLFDNITS", "length": 480 }, "evidence": [ { "id": "A0A8V1AFN2", "url": "https://omabrowser.org/oma/group/A0A8V1AFN2/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9Y5Q8-1", "protein_name": "General transcription factor 3C polypeptide 5", "gene_name": "GTF3C5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAEAADLGLGAAVPVELRRERRMVCVEYPGVVRDVAKMLPTLGGEEGVSRIYADPTKRLELYFRPKDPYCHPVCANRFSTSSLLLRIRKRTRRQKGVLGTEAHSEVTFDMEILGIISTIYKFQGMSDFQYLAVHTEAGGKHTSMYDKVLMLRPEKEAFFHQELPLYIPPPIFSRLDAPVDYFYRPETQHREGYNNPPISGENLIGLSRARRPHNAIFVNFEDEEVPKQPLEAAAQTWRRVCTNPVDRKVEEELRKLFDIRPIWSRNAVKANISVHPDKLKVLLPFIAYYMITGPWRSLWIRFGYDPRKNPDAKIYQVLDFRIRCGMKHGYAPSDLPVKAKRSTYNYSLPITVKKTSSQLVTMHDLKQGLGPSGTSGARKPASSKYKLKDSVYIFREGALPPYRQMFYQLCDLNVEELQKIIHRNDGAENSCTERDGWCLPKTSDELRDTMSLMIRQTIRSKRPALFSSSAKADGGKEQLTYESGEDEEDEEEEEEEEEDFKPSDGSENEMETEILDYV", "length": 519 }, "evidence": [ { "id": "A0A8V1AFN2", "url": "https://omabrowser.org/oma/group/A0A8V1AFN2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "transcription factor TFIIIC complex", "id": "GO:0000127", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000127", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFN2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFN2" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFN2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFN2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "5S class rRNA transcription by RNA polymerase III", "id": "GO:0042791", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042791", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFN2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFN2" } ], "pmid": "" }, { "name": "transcription initiation at RNA polymerase III promoter", "id": "GO:0006384", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006384", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFN2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFN2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFN2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFN2" } ], "pmid": "" }, { "name": "RNA polymerase III general transcription initiation factor activity", "id": "GO:0000995", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000995", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFN2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFN2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 265, "end_pos": 267, "annotation": "n_glycosylation_sequon" }, { "start_pos": 339, "end_pos": 341, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AFN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFN2" }, { "id": "PF09734", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09734" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Transcription factor IIIC subunit 5 HTH", "eco_id": "ECO_0000259", "start_pos": 162, "end_pos": 315, "start_aa": "Ile", "end_aa": "Arg", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1AFN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFN2" }, { "id": "PF17682", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17682" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Transcription factor IIIC subunit Tfc1/Sfc1 triple barrel", "eco_id": "ECO_0000259", "start_pos": 24, "end_pos": 126, "start_aa": "Val", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 265, "end_pos": 267 }, { "start_pos": 339, "end_pos": 341 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 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"count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AFS7-1", "uniprot_ac": "A0A8V1AFS7", "uniprot_id": "A0A8V1AFS7_CHICK", "mass": { "chemical_mass": 28925.0, "monoisotopic_mass": 28925.0 }, "refseq": { "ac": "XP_001235153", "name": "UPF0739 protein C1orf74 homolog", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001235153" }, "gene_names": [ { "name": "C1orf74", "type": "recommended", "evidence": [ { "id": "A0A8V1AFS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFS7" } ] }, { "name": "C1orf74", "type": "synonym", "evidence": [ { "id": "XP_001235153", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001235153" } ] } ], "protein_names": [ { "name": "Chromosome 1 open reading frame 74", "type": "synonym", "evidence": [ { "id": "A0A8V1AFS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFS7/entry#names_and_taxonomy" } ] }, { "name": "UPF0739 protein C1orf74 homolog", "type": "synonym", "evidence": [ { "id": "XP_001235153", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001235153" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052557.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_001235153.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_001235153", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001235153" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFS7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFS7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "C1orf74", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFS7", "locus": { "chromosome": "26", "start_pos": 3201297, "end_pos": 3202124, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027743", "url": "https://www.ensembl.org/id/ENSGALG00010027743" } ] } } ], "crossref": [ { "id": "A0A8V1AFS7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AFS7", "database": "AlphaFoldDB", "categories": [] }, { "id": "771943", "url": "https://www.ncbi.nlm.nih.gov/gene/771943", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR027850", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027850", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:771943", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:771943", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YPVTYWF", "url": "https://omabrowser.org/oma/group/YPVTYWF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AFS7", "url": "https://www.orthodb.org/?gene=A0A8V1AFS7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31366", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31366", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31366:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31366:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14953", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14953", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_001235153", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001235153", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AFS7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFS7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFS7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFS7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGPAARSEAQGVLPAPQLVAAAREALGAGSRRRLAAARALQLAGEVLAVAAGLKPALLYDCGAAGPAELRRYVERLWEAGLGLCRLHLLGVAGDVLLLHPGRARRRLEAALRAHPAPFMDVAAARSSPALCGPAEAAAIRGHLEALLAHLVAAEEAASSPVSCSEVVATGWNLCTVFGVLLGYPAAYTFPVEEGAENCLALTPLRVFTAQASCPRIQGGLRVQIYSFSIPESLCMELQEVLDAWREELRDDFCAQSDFIDLCISSEVVLLPAVAL", "length": 275, "header": "tr|A0A8V1AFS7-1|A0A8V1AFS7_CHICK Isoform 1 of Chromosome 1 open reading frame 74 OS=Gallus gallus OX=9031 GN=C1orf74 PE=3 SV=1 CANONICAL=A0A8V1AFS7-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AFS7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFS7/entry#A0A8V1AFS7-1", "sequence": { "sequence": "MGPAARSEAQGVLPAPQLVAAAREALGAGSRRRLAAARALQLAGEVLAVAAGLKPALLYDCGAAGPAELRRYVERLWEAGLGLCRLHLLGVAGDVLLLHPGRARRRLEAALRAHPAPFMDVAAARSSPALCGPAEAAAIRGHLEALLAHLVAAEEAASSPVSCSEVVATGWNLCTVFGVLLGYPAAYTFPVEEGAENCLALTPLRVFTAQASCPRIQGGLRVQIYSFSIPESLCMELQEVLDAWREELRDDFCAQSDFIDLCISSEVVLLPAVAL", "length": 275, "header": "tr|A0A8V1AFS7-1|A0A8V1AFS7_CHICK Isoform 1 of Chromosome 1 open reading frame 74 OS=Gallus gallus OX=9031 GN=C1orf74 PE=3 SV=1 CANONICAL=A0A8V1AFS7-1" }, "locus": { "chromosome": "26", "start_pos": 3202124, "end_pos": 3201300, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067258.1", "url": "https://www.ensembl.org/id/ENSGALT00010067258.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041162.1", "url": "https://www.ensembl.org/id/ENSGALP00010041162.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:771943", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:771943", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A6QQA5-1", "protein_name": "UPF0739 protein C1orf74 homolog", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSTPSPQLLVAAAQQTLGMGKRRGPPRAVCLHLAGEVLAVARGLKPALLYDCSSAGAPEIQSYLEKLRGLGFPTQGLHVLEIAENSLIVHPEYVRRHLEQVLLGSIAFVDVSGSQPYPAVCSLDQLQDFKALVVEIITHLQGLQRDRSLAVSCSRLCSSAWNLCTVFGILLGYPVPYTFHENQGEDNCLAQTPLRVFTARISWLCCQPPVLLYSFSVPESLFLSLRDILNTWEKDLRTRCRTQNDFADLSISSEIVTLPAVAL", "length": 263 }, "evidence": [ { "id": "A0A8V1AFS7", "url": "https://omabrowser.org/oma/group/A0A8V1AFS7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1SF50-1", "protein_name": "Chromosome 9 C1orf74 homolog", "gene_name": "C1orf74", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSTLSLQLLVAAAQQTLGMGRSRGPPRAVCLHLAGEVLAVARGLKPALLYDCNCAGAAELQSYLEQLQGLGFPTRGLHILEIGEDSLIVCPERVCQHLEQVLLGSVAFVDVSSAQPHPSVCSLDQLQDLKALLAEIIAHLQGLKTDLSLAVSSSRLCSSDWNLCTVFGILLGYPVPYTFHVSQGGDNCLALTPLRVFTARISWRHSQPPVLLYSFSVPESLFPALRDILNTWEKDLRTRCRTQNDFADLSISSEVVTLPAVAL", "length": 263 }, "evidence": [ { "id": "A0A8V1AFS7", "url": "https://omabrowser.org/oma/group/A0A8V1AFS7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q567C3-1", "protein_name": "UPF0739 protein C1orf74 homolog", "gene_name": "", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MVASSPETLISAAQKCLCSRKKRLSPSSCLEVTIHIIAVDLGVKPALLYDSNGASPDQLQLYLHSLQESSVVSNSLRIMSINDNTFIINPDIMKSHLGELLKSKSLPLIDVCSSRKRPVLCAFERSAEEMVRSFLEVFMNGLDLVVLEEELYKDWNLCTFFGILLGYPASYWFEQTQGFENCLSMTPLVVCTVWVRWQIHEIKQRCCLYSFSVPEELWSDVQSHIQRWTDHLRERFSKQTVLTDICFSRDTVTLPSVTL", "length": 259 }, "evidence": [ { "id": "A0A8V1AFS7", "url": "https://omabrowser.org/oma/group/A0A8V1AFS7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q5U2R2-1", "protein_name": "UPF0739 protein C1orf74 homolog", "gene_name": "", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSTPSPQLLVAAAQRTLGMGKRKCPPRATCLHLAGEVLAVARGLKPAVLYDCNSAGVLALQSYLEELQGLGFLKPGLHILEIGENNLIVSPEYTCQHLEQTLLGTVAFVDVSCSQPHPSVLSLDQLPGLKSLIADIITRFQELLKGVSPGVSYSKLHSSDWNLCTLFGILLGYPVSYTFDLNHGEGNCLTMTPLRVFTAQISWLSGQPPVPLYSFSVPESLFPPLRNFLSAWEKELRTRFRAQNAFADLSISSEVVTLPAVAL", "length": 263 }, "evidence": [ { "id": "A0A8V1AFS7", "url": "https://omabrowser.org/oma/group/A0A8V1AFS7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q96LT6-1", "protein_name": "UPF0739 protein C1orf74", "gene_name": "C1orf74", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLLLDLMSSPSPQLLVAAAQQTLGMGKRRSPPQAICLHLAGEVLAVARGLKPAVLYDCNCAGASELQSYLEELKGLGFLTFGLHILEIGENSLIVSPEHVCQHLEQVLLGTIAFVDVSSCQRHPSVCSLDQLQDLKALVAEIITHLQGLQRDLSLAVSYSRLHSSDWNLCTVFGILLGYPVPYTFHLNQGDDNCLALTPLRVFTARISWLLGQPPILLYSFSVPESLFPGLRDILNTWEKDLRTRFRTQNDFADLSISSEIVTLPAVAL", "length": 269 }, "evidence": [ { "id": "A0A8V1AFS7", "url": "https://omabrowser.org/oma/group/A0A8V1AFS7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9DAE8-1", "protein_name": "UPF0739 protein C1orf74 homolog", "gene_name": "", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSTPSPQLLVAAAQQTLGMGKRKCPPRATCLHLAGEVLAVARGLKPAVLYDCNSAGVLALQSYLEELQGLGFLEPGLHILEIGENNFIVSPEYACQHLEQTLLGTVAFVDVSRSQPHPSVRSVDQLPDLKSLIADVITRFRGLKKDVSQGVSYTRLHSSDWNLCTVFGILLGYPVSYTFDLNREDDNCLTMTPLRVFTARISWLPGQPSILLYSFSVPESLFPALKNFLSAWEKELRTRFRAQNAFADLSISSEVVTLPAVAL", "length": 263 }, "evidence": [ { "id": "A0A8V1AFS7", "url": "https://omabrowser.org/oma/group/A0A8V1AFS7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AFU8-1", "uniprot_ac": "A0A8V1AFU8", "uniprot_id": "A0A8V1AFU8_CHICK", "mass": { "chemical_mass": 128864.0, "monoisotopic_mass": 128864.0 }, "refseq": { "ac": "XP_015135273", "name": "sarcosine dehydrogenase, mitochondrial isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015135273" }, "gene_names": [ { "name": "SARDH", "type": "recommended", "evidence": [ { "id": "A0A8V1AFU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFU8" } ] }, { "name": "SARDH", "type": "synonym", "evidence": [ { "id": "XP_015135273", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015135273" } ] } ], "protein_names": [ { "name": "Sarcosine dehydrogenase, mitochondrial", "type": "recommended", "evidence": [ { "id": "A0A8V1AFU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFU8/entry#names_and_taxonomy" } ] }, { "name": "1.5.8.3", "type": "synonym", "evidence": [ { "id": "A0A8V1AFU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFU8/entry#names_and_taxonomy" } ] }, { "name": "sarcosine dehydrogenase, mitochondrial isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015135273", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015135273" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052548.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 1, 2022 this sequence version replaced XP_015135273.3. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015135273", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015135273" } ] }, { "annotation": "Catalyzes the last step of the oxidative degradation of choline to glycine. Converts sarcosine into glycine.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALX0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALX0#function" }, { "database": "UniProtKB", "id": "ARBA00059128", "url": "https://www.uniprot.org/uniprotkb/ARBA00059128#function" }, { "database": "UniProtKB", "id": "A0A8V1AFU8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFU8#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFU8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFU8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SARDH", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFU8", "locus": { "chromosome": "17", "start_pos": 7632462, "end_pos": 7653704, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028881", "url": "https://www.ensembl.org/id/ENSGALG00010028881" } ] } } ], "crossref": [ { "id": "A0A8V1AFU8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AFU8", "database": "AlphaFoldDB", "categories": [] }, { "id": "417146", "url": "https://www.ncbi.nlm.nih.gov/gene/417146", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006076", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006076", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006222", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006222", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013977", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013977", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027266", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027266", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028896", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028896", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029043", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029043", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032503", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032503", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036188", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036188", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:417146", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417146", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RISPFCP", "url": "https://omabrowser.org/oma/group/RISPFCP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AFU8", "url": "https://www.orthodb.org/?gene=A0A8V1AFU8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ALX0", "url": "https://www.orthodb.org/?gene=A0A8V1ALX0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR43757", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43757", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR43757:SF11", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43757:SF11", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01266", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01266", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01571", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01571", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08669", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08669", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16350", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16350", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015135273", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015135273", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "19793", "url": "https://www.rhea-db.org/rhea/19793", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1AFU8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFU8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFU8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFU8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALX0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALX0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALX0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALX0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQPCSAVVLGAQQLHVAPCDPLRVCTDKWGIIHRAQPVPYAVTRPGAAFPEALTGASISSPQLAPALRPRRGKAAPDTSSILSSFFLFAAADIISHISWTGQGAALSKHSTGTGCTCWLPSANSSVPRALLADPEHALSLGGLWPASTWPPPSATPQQAALRATRGGNPEPENKGPNSSANGETEPLSPVGCEPPQPCCPLSAGRRAGKRSHSSIPFRISPFCPTLPLSGGATRRTGAGGRRCGRGGGGGGGGEHRRKADVPRPSRASLVDMSYVSCALRVAALCRLPAPWRSPRPYSSATGPTAEKSVPYQKTLKEESNGSTGPSQPPPASAEVVVVGGGSLGCQTTYHLAKLGITNVVLLERDRLTAGTTWHTAGLLWQLRPSDVEVELLAHTRDVVSRDLPAETGLHTGWVQNGGLFIASNKQRLDEYKRLMSLGKVYGVESHVLTPAQTKELYPLMNVDDLYGTLYVPKDGTMDPAGTCSTLARAAAARGATIIENCPVTGIQVRTDDFGVKRVHAVETAHGTIQTPCVVNCAGVWARALGRLAGVHVPLVAMHHAYVVTERIEGIQNMPNVRDHDASVYLRLQGDALSVGGYESNPIFWEEVSEKFAFSLFDLDWDVFMQHIQGAINRVPVLERTGIKSTVCGPESFTADHKPLMGEAPEVRGFFLGCGFNSAGMMLGGGCGKELAHWIIHGRPEKDMYGYDIRRFHCSLTDNNRWIRERSHESYAKNYSVVFPHDEPLAGRNMRKDPLHQELLQQGCVFQERHGWERPGWFSPGGAAPVLDYDYYGAYSQEQHRDYTYNQLLADEYTFDFPPHHNIIKKECLTCRNALALFNMSYFGKFYLVGPEATKAANWLFSADVSKAPGSTVYTCMLNKRGGVESDLTVSRISPGDPSSPLAPAFQGDGYYLAIGGAVAQHNWSHITAVLQDMKLQCKLIDCSEELGMMSLQGPLSRTVLQELLDTDLSNEAFPFSTHRLVKAAGCTVRAMRLSFVGELGWELHVPREDCVRVYQAVMEAGARHGITNAGYRAIDSLSIEKGYRHWHADLRPDDTPLEAGLAFTCKLKSSIPFLGWEAVEAQKSAGIFRRLVCFTTDEKVPMFGLEAIWRDGEVVGHIRRADFGFAIDKTIAYGYIRDPAGGPVSLDFVRSGNYELERMGVRYPAQAHTKSPFDPDNKRVKGIY", "length": 1184, "header": "tr|A0A8V1AFU8-1|A0A8V1AFU8_CHICK Isoform 1 of Sarcosine dehydrogenase, mitochondrial OS=Gallus gallus OX=9031 GN=SARDH PE=1 SV=1 CANONICAL=A0A8V1AFU8-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AFU8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFU8/entry#A0A8V1AFU8-1", "sequence": { "sequence": "MQPCSAVVLGAQQLHVAPCDPLRVCTDKWGIIHRAQPVPYAVTRPGAAFPEALTGASISSPQLAPALRPRRGKAAPDTSSILSSFFLFAAADIISHISWTGQGAALSKHSTGTGCTCWLPSANSSVPRALLADPEHALSLGGLWPASTWPPPSATPQQAALRATRGGNPEPENKGPNSSANGETEPLSPVGCEPPQPCCPLSAGRRAGKRSHSSIPFRISPFCPTLPLSGGATRRTGAGGRRCGRGGGGGGGGEHRRKADVPRPSRASLVDMSYVSCALRVAALCRLPAPWRSPRPYSSATGPTAEKSVPYQKTLKEESNGSTGPSQPPPASAEVVVVGGGSLGCQTTYHLAKLGITNVVLLERDRLTAGTTWHTAGLLWQLRPSDVEVELLAHTRDVVSRDLPAETGLHTGWVQNGGLFIASNKQRLDEYKRLMSLGKVYGVESHVLTPAQTKELYPLMNVDDLYGTLYVPKDGTMDPAGTCSTLARAAAARGATIIENCPVTGIQVRTDDFGVKRVHAVETAHGTIQTPCVVNCAGVWARALGRLAGVHVPLVAMHHAYVVTERIEGIQNMPNVRDHDASVYLRLQGDALSVGGYESNPIFWEEVSEKFAFSLFDLDWDVFMQHIQGAINRVPVLERTGIKSTVCGPESFTADHKPLMGEAPEVRGFFLGCGFNSAGMMLGGGCGKELAHWIIHGRPEKDMYGYDIRRFHCSLTDNNRWIRERSHESYAKNYSVVFPHDEPLAGRNMRKDPLHQELLQQGCVFQERHGWERPGWFSPGGAAPVLDYDYYGAYSQEQHRDYTYNQLLADEYTFDFPPHHNIIKKECLTCRNALALFNMSYFGKFYLVGPEATKAANWLFSADVSKAPGSTVYTCMLNKRGGVESDLTVSRISPGDPSSPLAPAFQGDGYYLAIGGAVAQHNWSHITAVLQDMKLQCKLIDCSEELGMMSLQGPLSRTVLQELLDTDLSNEAFPFSTHRLVKAAGCTVRAMRLSFVGELGWELHVPREDCVRVYQAVMEAGARHGITNAGYRAIDSLSIEKGYRHWHADLRPDDTPLEAGLAFTCKLKSSIPFLGWEAVEAQKSAGIFRRLVCFTTDEKVPMFGLEAIWRDGEVVGHIRRADFGFAIDKTIAYGYIRDPAGGPVSLDFVRSGNYELERMGVRYPAQAHTKSPFDPDNKRVKGIY", "length": 1184, "header": "tr|A0A8V1AFU8-1|A0A8V1AFU8_CHICK Isoform 1 of Sarcosine dehydrogenase, mitochondrial OS=Gallus gallus OX=9031 GN=SARDH PE=1 SV=1 CANONICAL=A0A8V1AFU8-1" }, "locus": { "chromosome": "17", "start_pos": 7653640, "end_pos": 7632780, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069850.1", "url": "https://www.ensembl.org/id/ENSGALT00010069850.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042976.1", "url": "https://www.ensembl.org/id/ENSGALP00010042976.1" } ] } }, { "isoform_ac": "A0A8V1ALX0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFU8/entry#A0A8V1ALX0-1", "sequence": { "sequence": "MSYVSCALRVAALCRLPAPWRSPRPYSSATGPTAEKSVPYQKTLKEESNGSTGPSQPPPASAETTYHLAKLGITNVVLLERDRLTAGTTWHTAGLLWQLRPSDVEVELLAHTRDVVSRDLPAETGLHTGWVQNGGLFIASNKQRLDEYKRLMSLGKVYGVESHVLTPAQTKELYPLMNVDDLYGTLYVPKDGTMDPAGTCSTLARAAAARGATIIENCPVTGIQVRTDDFGVKRVHAVETAHGTIQTPCVVNCAGVWARALGRLAGVHVPLVAMHHAYVVTERIEGIQNMPNVRDHDASVYLRLQGDALSVGGYESNPIFWEEVSEKFAFSLFDLDWDVFMQHIQGAINRVPVLERTGIKSTVCGPESFTADHKPLMGEAPEVRGFFLGCGFNSAGMMLGGGCGKELAHWIIHGRPEKDMYGYDIRRFHCSLTDNNRWIRERSHESYAKNYSVVFPHDEPLAGRNMRKDPLHQELLQQGCVFQERHGWERPGWFSPGGAAPVLDYDYYGAYSQEQHRDYTYNQLLADEYTFDFPPHHNIIKKECLTCRNALALFNMSYFGKFYLVGPEATKAANWLFSADVSKAPGSTVYTCMLNKRGGVESDLTVSRISPGDPSSPLAPAFQGDGYYLAIGGAVAQHNWSHITAVLQDMKLQCKLIDCSEELGMMSLQGPLSRTVLQELLDTDLSNEAFPFSTHRLVKAAGCTVRAMRLSFVGELGWELHVPREDCVRVYQAVMEAGARHGITNAGYRAIDSLSIEKGYRHWHADLRPDDTPLEAGLAFTCKLKSSIPFLGWEAVEAQKSAGIFRRLVCFTTDEKVPMFGLEAIWRDGEVVGHIRRADFGFAIDKTIAYGYIRDPAGGPVSLDFVRSGNYELERMGVRYPAQAHTKSPFDPDNKRVKGIY", "length": 901, "header": "tr|A0A8V1ALX0-1|A0A8V1AFU8_CHICK Computationally mapped isoform of Sarcosine dehydrogenase, mitochondrial OS=Gallus gallus OX=9031 GN=SARDH PE=1 SV=1 CANONICAL=A0A8V1AFU8-1" }, "locus": { "chromosome": "17", "start_pos": 7651011, "end_pos": 7632780, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069849.1", "url": "https://www.ensembl.org/id/ENSGALT00010069849.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042975.1", "url": "https://www.ensembl.org/id/ENSGALP00010042975.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 304, "start_aa": "Thr", "end_pos": 304, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr304", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 43, "start_aa": "Thr", "end_pos": 43, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr43", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:417146", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417146", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFU8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFU8" } ], "pmid": "" }, { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFU8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFU8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "glycine decarboxylation via glycine cleavage system", "id": "GO:0019464", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019464", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFU8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFU8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "aminomethyltransferase activity", "id": "GO:0004047", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004047", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFU8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFU8" } ], "pmid": "" }, { "name": "sarcosine dehydrogenase activity", "id": "GO:0008480", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008480", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFU8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFU8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 123, "end_pos": 125, "annotation": "n_glycosylation_sequon" }, { "start_pos": 177, "end_pos": 179, "annotation": "n_glycosylation_sequon" }, { "start_pos": 320, "end_pos": 322, "annotation": "n_glycosylation_sequon" }, { "start_pos": 733, "end_pos": 735, "annotation": "n_glycosylation_sequon" }, { "start_pos": 838, "end_pos": 840, "annotation": "n_glycosylation_sequon" }, { "start_pos": 922, "end_pos": 924, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "19793", "name": "", "equation": "(6S)-5,6,7,8-tetrahydrofolyl-(gamma-L-Glu)(n) + sarcosine + oxidized [electron-transfer flavoprotein] + H(+) = (6R)-5,10-methylenetetrahydrofolyl-(gamma-L-Glu)(n) + reduced [electron-transfer flavoprotein] + glycine", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V1AFU8-1" ], "evidence": [ { "id": "19793", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/19793" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A8V1AFU8", "gene_name": "SARDH", "activity": [ { "ec_number": "1.5.8.3", "activity": "(6S)-5,6,7,8-tetrahydrofolyl-(gamma-L-Glu)(n) + sarcosine + oxidized [electron-transfer flavoprotein] + H(+) = (6R)-5,10-methylenetetrahydrofolyl-(gamma-L-Glu)(n) + reduced [electron-transfer flavoprotein] + glycine.", "evidence": [ { "id": "A0A8V1AFU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFU8" } ] }, { "ec_number": "1.5.8.3", "activity": "", "evidence": [ { "id": "A0A8V1AFU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFU8" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AFU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFU8" }, { "id": "PF08669", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08669" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Aminomethyltransferase C-terminal", "eco_id": "ECO_0000259", "start_pos": 1089, "end_pos": 1173, "start_aa": "Arg", "end_aa": "Phe", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1AFU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFU8" }, { "id": "PF01266", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01266" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "FAD dependent oxidoreductase", "eco_id": "ECO_0000259", "start_pos": 335, "end_pos": 693, "start_aa": "Val", "end_aa": "Trp", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1AFU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFU8" }, { "id": "PF16350", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16350" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "FAD dependent oxidoreductase central", "eco_id": "ECO_0000259", "start_pos": 696, "end_pos": 750, "start_aa": "His", "end_aa": "Arg", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1AFU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFU8" }, { "id": "PF01571", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01571" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "GCVT N-terminal", "eco_id": "ECO_0000259", "start_pos": 754, "end_pos": 1068, "start_aa": "Leu", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "1.5.8.3", "ec_name": "(6S)-5,6,7,8-tetrahydrofolyl-(gamma-L-Glu)(n) + sarcosine + oxidized [electron-transfer flavoprotein] + H(+) = (6R)-5,10-methylenetetrahydrofolyl-(gamma-L-Glu)(n) + reduced [electron-transfer flavoprotein] + glycine.", "evidence": [ { "id": "1.5.8.3", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:1.5.8.3" }, { "id": "1.5.8.3", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=1.5.8.3" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 43, 304 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 123, "end_pos": 125 }, { "start_pos": 177, "end_pos": 179 }, { "start_pos": 320, "end_pos": 322 }, { "start_pos": 733, "end_pos": 735 }, { "start_pos": 838, "end_pos": 840 }, { "start_pos": 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"id": "ENSGALG00010027293", "url": "https://www.ensembl.org/id/ENSGALG00010027293" } ] } } ], "crossref": [ { "id": "A0A8V1AFV4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AFV4", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd19495", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19495", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR018627", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018627", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AFV4", "url": "https://www.orthodb.org/?gene=A0A8V1AFV4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16184", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16184", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { 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"id": "GO:0002098", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002098", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFV4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFV4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 402, "end_pos": 404, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 402, "end_pos": 404 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": 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"mass": { "chemical_mass": 18817.0, "monoisotopic_mass": 18817.0 }, "refseq": { "ac": "XP_046759954", "name": "feather keratin 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046759954" }, "gene_names": [ { "name": "LOC100857468", "type": "recommended", "evidence": [ { "id": "A0A8V1AFW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFW8" } ] }, { "name": "LOC100857468", "type": "synonym", "evidence": [ { "id": "XP_046759954", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046759954" } ] } ], "protein_names": [ { "name": "Keratin", "type": "recommended", "evidence": [ { "id": "A0A8V1AFW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFW8/entry#names_and_taxonomy" } ] }, { "name": "feather keratin 1", "type": "synonym", "evidence": [ { "id": "XP_046759954", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046759954" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052556.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_046759954", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046759954" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFW8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFW8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC100857468", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFW8", "locus": {} } ], "crossref": [ { "id": "A0A8V1AFW8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AFW8", "database": "AlphaFoldDB", "categories": [] }, { "id": "100857468", "url": "https://www.ncbi.nlm.nih.gov/gene/100857468", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003461", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003461", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:100857468", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100857468", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1AFW8", "url": "https://www.orthodb.org/?gene=A0A8V1AFW8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31203", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31203", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31203:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31203:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02422", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02422", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_046759954", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046759954", 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}, { "name": "Ca(2+)/calmodulin-dependent protein kinase phosphatase", "type": "synonym", "evidence": [ { "id": "A0A8V0ZS02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS02/entry#names_and_taxonomy" } ] }, { "name": "protein phosphatase 1F isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015131169", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015131169" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052546.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015131169.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015131169", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015131169" } ] }, { "annotation": "Dephosphorylates and concomitantly deactivates CaM-kinase II activated upon autophosphorylation, and CaM-kinases IV and I activated upon phosphorylation by CaM-kinase kinase. Promotes apoptosis.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZS02", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS02#function" }, { "database": "UniProtKB", "id": "ARBA00056926", "url": "https://www.uniprot.org/uniprotkb/ARBA00056926#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZS02", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS02" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PPM1F", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS02", "locus": { "chromosome": "15", "start_pos": 508302, "end_pos": 488149, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010024346", "url": "https://www.ensembl.org/id/ENSGALG00010024346" } ] } } ], "crossref": [ { "id": "A0A8V0ZS02", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZS02", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00143", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00143", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "416772", "url": "https://www.ncbi.nlm.nih.gov/gene/416772", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000222", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000222", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001932", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001932", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015655", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015655", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036457", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036457", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "DEMFLFK", "url": "https://omabrowser.org/oma/group/DEMFLFK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZS02", "url": "https://www.orthodb.org/?gene=A0A8V0ZS02", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A175", "url": "https://www.orthodb.org/?gene=A0A8V1A175", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13832", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13832", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13832:SF233", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13832:SF233", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00481", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00481", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015131169", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015131169", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "20629", "url": "https://www.rhea-db.org/rhea/20629", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "47004", "url": "https://www.rhea-db.org/rhea/47004", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZS02", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS02", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZS02-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS02-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A175", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A175", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A175-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A175-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MALEAEAAGAPLGSFLRDFPSALGPGEPLPWSSAGSGAVSEAEAPGALAELARNLLGGSRGVSPLLAASLIHAAVDEVLRTDLTEFKKESVERQGEGDEERLTLLDGELLQRCFFNKLRDVCFEWQKQLPPLRSLKRFLLVSIHAIRNTRRKMEDRHVILTEFNQLFGLADDIDRAYFAIFDGHGGVDAANYSATHLHVNVGLHEEIVKNPAEALKCSFRKTDEMFLLKAKRERLRSGTTGVSALIVGNKLHIAWLGDSQVMLVQQGNAVTLMEPHKPEREDERARIEALGGCVTYMDCWRVNGTLAVSRAIGDVCQKPYISGDADGDTFDLTGSEDYLLLACDGFFDAVKPYEVVDLVLDHLMQTKGVGLKAAERLVAAAKENGSNDNITVLVVFLRDPQDILADCLRDTKSLEAGDDARSSPFNFLSCEAAATQ", "length": 436, "header": "tr|A0A8V0ZS02-1|A0A8V0ZS02_CHICK Isoform 1 of Protein phosphatase 1F OS=Gallus gallus OX=9031 GN=PPM1F PE=1 SV=1 CANONICAL=A0A8V0ZS02-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZS02-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS02/entry#A0A8V0ZS02-1", "sequence": { "sequence": "MALEAEAAGAPLGSFLRDFPSALGPGEPLPWSSAGSGAVSEAEAPGALAELARNLLGGSRGVSPLLAASLIHAAVDEVLRTDLTEFKKESVERQGEGDEERLTLLDGELLQRCFFNKLRDVCFEWQKQLPPLRSLKRFLLVSIHAIRNTRRKMEDRHVILTEFNQLFGLADDIDRAYFAIFDGHGGVDAANYSATHLHVNVGLHEEIVKNPAEALKCSFRKTDEMFLLKAKRERLRSGTTGVSALIVGNKLHIAWLGDSQVMLVQQGNAVTLMEPHKPEREDERARIEALGGCVTYMDCWRVNGTLAVSRAIGDVCQKPYISGDADGDTFDLTGSEDYLLLACDGFFDAVKPYEVVDLVLDHLMQTKGVGLKAAERLVAAAKENGSNDNITVLVVFLRDPQDILADCLRDTKSLEAGDDARSSPFNFLSCEAAATQ", "length": 436, "header": "tr|A0A8V0ZS02-1|A0A8V0ZS02_CHICK Isoform 1 of Protein phosphatase 1F OS=Gallus gallus OX=9031 GN=PPM1F PE=1 SV=1 CANONICAL=A0A8V0ZS02-1" }, "locus": { "chromosome": "15", "start_pos": 500696, "end_pos": 488259, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010059382.1", "url": "https://www.ensembl.org/id/ENSGALT00010059382.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036256.1", "url": "https://www.ensembl.org/id/ENSGALP00010036256.1" } ] } }, { "isoform_ac": "A0A8V1A175-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS02/entry#A0A8V1A175-1", "sequence": { "sequence": "MALEAEAAGAPLGSFLRDFPSALGPGEPLPWSSAGSGAVSEAEAPGALAELARNLLGGRGVSPLLAASLIHAAVDEVLRTDLTEFKKESVERQGEGDEERLTLLDGELLQRCFFNKLRDVCFEWQKQLPPLRSLKRFLLVSIHAIRNTRRKMEDRHVILTEFNQLFGLADDIDRAYFAIFDGHGGVDAANYSATHLHVNVGLHEEIVKNPAEALKCSFRKTDEMFLLKAKRERLRSGTTGVSALIVGNKLHIAWLGDSQVMLVQQGNAVTLMEPHKPEREDERARIEALGGCVTYMDCWRVNGTLAVSRAIGDVCQKPYISGDADGDTFDLTGSEDYLLLACDGFFDAVKPYEVRHGDSYSSFVGGSGILNCVPGQLSYPSALGVAKNCLMYLLAYFKKLLQSSDWKQVRRRTLHCRICCF", "length": 421, "header": "tr|A0A8V1A175-1|A0A8V0ZS02_CHICK Computationally mapped isoform of Protein phosphatase 1F OS=Gallus gallus OX=9031 GN=PPM1F PE=1 SV=1 CANONICAL=A0A8V0ZS02-1" }, "locus": { "chromosome": "15", "start_pos": 508268, "end_pos": 488259, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010059380.1", "url": "https://www.ensembl.org/id/ENSGALT00010059380.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036254.1", "url": "https://www.ensembl.org/id/ENSGALP00010036254.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A2BE49-1", "protein_name": "Protein phosphatase 1F", "gene_name": "ppm1f", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSGAEKGDVRTFLESFLQEFSKPLGTEDPLPVSSANRIISLQELKGESLDLGLRLLSARNAPSWLAAVMCNVAVTELLKDDLTPHYCPKDPEQQPEDEQGVVLLQSEPVLRLFINKLRAVGVAWQKQPPNPDAPSSRTHSCSVHAIRNTRRKMEDRHVILKEFNQLLGLQDGVGREYYAVFDGHGGVDAATYSATHLHIVLSQQGELKTDAATAFKNTFTQTDDMFKIKAKRERLRSGSTGVAVLLTSDLLTVSWLGDSQALLVRQGEPVTLMDPHKPEREDEKKRIEDLGGCIAFMGCWRVNGTYAVSRAIGDFDQKPYVSNEADSSSFHLTGDEDYVLLACDGFFDVIRPADVPALVLEALRESGGSGNDVAQSLVAQAKTAGSSDNITVLLVFLKEPQKLLAHDTVCRTEGRGAACAAAGV", "length": 424 }, "evidence": [ { "id": "A0A8V0ZS02", "url": "https://omabrowser.org/oma/group/A0A8V0ZS02/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E1BF95-1", "protein_name": "Protein phosphatase 1F", "gene_name": "PPM1F", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MASGAPQQNGQTAEETPGFLDTLLRDFPAPLSPESPLPWKVPGPVLTLEEVEGELAEVAMGFLSSRSAPPPLAACLAHEAVSQLLQSDLSEFRKLPEQEEEDGDRGDRAEEKAPVTLLDAAGLARSLFDRLWQACGQWQQQVPAAARAPQRQWLVSAHAIRNARRRMEDRHVCLPAFNLLFGLEDSVDRAYFAVFDGHGGADAARYASVHVHAVAARRPELAADPAEALRAAFRRTDEMFLWKARRERLQSGTTGVCALIAGNTLHVAWLGDSQVLLVRQGQAVKLMEPHRPERQDEKDRIEALGGFVSHMDCWRVNGTLAVSRAIGDVFQKPYVSGEADAASWELTGSEEYLLLACDGFFDVVPHQEVASLVRSRLAGPQGSGLRVAEELVAAARERGSHDNITVVVVFLRDPQDLLEPEPDAPRS", "length": 427 }, "evidence": [ { "id": "A0A8V0ZS02", "url": "https://omabrowser.org/oma/group/A0A8V0ZS02/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1RL04-1", "protein_name": "Protein phosphatase 1F", "gene_name": "PPM1F", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MASGASQQDSQTAEEIPSFLDVFLHDFPAPLSPDSPLPWKVPGVVLSQEEVEGELAELAMGLLGSRNAPPLLAASLAHEAVSRLLQMDLSEFRKLLKQEDEDGDEEEKAPVTLLDAAGLARSLFNQLWEVCSQQQVQEHEPVEAQVLQRPWLVSVHAVRNARRRMEDRHVCLPAFNQLFGLSDSVDRAYFAVFDGHGGVDAARYASVHVHANAARQPELPTDPAAALRAAFRCTDEMFLRKAKRERLQSGTTGVCALIAGSTLHVAWLGDSQVLLVQQGQVVKLMEPHRPERQDEKDRIEALGGFVSHVDCWRVNGTLAVSRAIGDVFQKPYVSGEADAASRELTGSEDYLLLACDGFFDVVPHQEVAGLVQSHLVGQEGSGQRVAEELVAAARERGSHDNITVMVVFLRDPRDLLEGGARGAGLSEPETPAAPRS", "length": 436 }, "evidence": [ { "id": "A0A8V0ZS02", "url": "https://omabrowser.org/oma/group/A0A8V0ZS02/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P49593-1", "protein_name": "Protein phosphatase 1F", "gene_name": "PPM1F", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSSGAPQKSSPMASGAEETPGFLDTLLQDFPALLNPEDPLPWKAPGTVLSQEEVEGELAELAMGFLGSRKAPPPLAAALAHEAVSQLLQTDLSEFRKLPREEEEEEEDDDEEEKAPVTLLDAQSLAQSFFNRLWEVAGQWQKQVPLAARASQRQWLVSIHAIRNTRRKMEDRHVSLPSFNQLFGLSDPVNRAYFAVFDGHGGVDAARYAAVHVHTNAARQPELPTDPEGALREAFRRTDQMFLRKAKRERLQSGTTGVCALIAGATLHVAWLGDSQVILVQQGQVVKLMEPHRPERQDEKARIEALGGFVSHMDCWRVNGTLAVSRAIGDVFQKPYVSGEADAASRALTGSEDYLLLACDGFFDVVPHQEVVGLVQSHLTRQQGSGLRVAEELVAAARERGSHDNITVMVVFLRDPQELLEGGNQGEGDPQAEGRRQDLPSSLPEPETQAPPRS", "length": 454 }, "evidence": [ { "id": "A0A8V0ZS02", "url": "https://omabrowser.org/oma/group/A0A8V0ZS02/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8CGA0-1", "protein_name": "Protein phosphatase 1F", "gene_name": "Ppm1f", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASGAAQNSSQMACDSEIPGFLDAFLQDFPAPLSLESPLPWKVPGTVLSQEEVEAELIELALGFLGSRNAPPSFAVAVTHEAISQLLQTDLSEFKRLPEQEEEEEEEEEEKALVTLLDAKGLARSFFNCLWKVCSQWQKQVPLTAQAPQWQWLVSIHAIRNTRRKMEDRHVSLPAFNHLFGLSDSVHRAYFAVFDGHGGVDAARYASVHVHTNASHQPELRTNPAAALKEAFRLTDEMFLQKAKRERLQSGTTGVCALIAGAALHVAWLGDSQVILVQQGRVVKLMEPHKPERQDEKARIEALGGFVSLMDCWRVNGTLAVSRAIGDVFQKPYVSGEADAASRELTGSEDYLLLACDGFFDVVPHHEVTGLVHGHLLRHKGNGMRIAEELVAVARDRGSHDNITVMVVFLREPLELLEGGVQGTGDAQADVGSQDLSTGLSELEISNTSQRS", "length": 452 }, "evidence": [ { "id": "A0A8V0ZS02", "url": "https://omabrowser.org/oma/group/A0A8V0ZS02/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9WVR7-1", "protein_name": "Protein phosphatase 1F", "gene_name": "Ppm1f", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASGAPQNSSQMACDGEIPGFLDTLLQDFPAPLSLESPLPWKVPGTVLGQEEVEAELTELAMGFLGSRNAPPAVAAAVTHEAISQLLQTDLSEFKRLPEQEEEEEEEEERVLTTLLDAKGLSRSFFNCLWEVCSQWQKRVPLTAQAPQRKWLVSIHAIRNTRRKMEDRHVSLPAFNHLFGLSDSVHRAYFAVFDGHGGVDAARYASVHVHTNASHQPELLTDPAAALKEAFRHTDQMFLQKAKRERLQSGTTGVCALITGAALHVAWLGDSQVILVQQGQVVKLMEPHKPERQDEKSRIEALGGFVSLMDCWRVNGTLAVSRAIGDVFQKPYVSGEADAASRELTGLEDYLLLACDGFFDVVPHHEIPGLVHGHLLRQKGSGMHVAEELVAVARDRGSHDNITVMVVFLRDPLELLEGGGQGAGGAQADVGSQDLSTGLSELEINTSQRS", "length": 450 }, "evidence": [ { "id": "A0A8V0ZS02", "url": "https://omabrowser.org/oma/group/A0A8V0ZS02/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "calmodulin-dependent protein phosphatase activity", "id": "GO:0033192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033192", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZS02", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS02" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZS02", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS02" } ], "pmid": "" }, { "name": "protein serine/threonine phosphatase activity", "id": "GO:0004722", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004722", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZS02", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS02" } ], "pmid": "" }, { "name": "protein tyrosine/serine/threonine phosphatase activity", "id": "GO:0008138", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008138", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZS02", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS02" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZS02", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS02" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZS02", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS02" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZS02", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS02" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 13, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZS02", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS02" } ], "pmid": "" }, { "name": "positive regulation of gene expression", "id": "GO:0010628", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010628", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZS02", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS02" } ], "pmid": "" }, { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZS02", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS02" } ], "pmid": "" }, { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZS02", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS02" } ], "pmid": "" }, { "name": "negative regulation of DNA-templated transcription", "id": "GO:0045892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045892", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZS02", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS02" } ], "pmid": "" }, { "name": "cellular response to xenobiotic stimulus", "id": "GO:0071466", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071466", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZS02", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS02" } ], "pmid": "" }, { "name": "positive regulation of stress fiber assembly", "id": "GO:0051496", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051496", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZS02", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS02" } ], "pmid": "" }, { "name": "positive regulation of focal adhesion assembly", "id": "GO:0051894", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051894", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZS02", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS02" } ], "pmid": "" }, { "name": "positive regulation of epithelial cell migration", "id": "GO:0010634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZS02", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS02" } ], "pmid": "" }, { "name": "positive regulation of chemotaxis", "id": "GO:0050921", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050921", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZS02", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS02" } ], "pmid": "" }, { "name": "positive regulation of growth", "id": "GO:0045927", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045927", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZS02", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS02" } ], "pmid": "" }, { "name": "negative regulation of protein transport", "id": "GO:0051224", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051224", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZS02", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS02" } ], "pmid": "" }, { "name": "negative regulation of cell-cell adhesion mediated by cadherin", "id": "GO:2000048", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000048", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZS02", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS02" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 191, "end_pos": 193, "annotation": "n_glycosylation_sequon" }, { "start_pos": 303, "end_pos": 305, "annotation": "n_glycosylation_sequon" }, { "start_pos": 384, "end_pos": 386, "annotation": "n_glycosylation_sequon" }, { "start_pos": 389, "end_pos": 391, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "20629", "name": "", "equation": "O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V1AB34-1", "A0A1D5PI23-1", "A0A8V0ZW37-1", "P62207-1", "F1P225-1", "P0C597-1", "P48463-1", "Q9PTJ6-1", "Q9PW71-1", "A0A8V0Z2T2-1", "A0A8V0ZYK3-1", "Q5ZJJ8-1", "Q5ZJQ7-1", "Q9YHA0-1", "A0A1D5PJC6-1", "A0A8V0XTW9-1", "A0A8V0XLK8-1", "A0A8V0Y1D0-1", "A0A8V0ZMU4-1", "A0A8V0ZMX1-1", "A0A8V0ZQ53-1", "A0A8V0ZFN2-1", "A0A8V0ZPJ8-1", "A0A8V0ZWA8-1", "A0A8V1A8D0-1", "E1BTX9-1", "E1BRQ8-1", "A0A8V0ZJ28-1", "A0A8V0XYX4-1", "A0A8V0ZE41-1", "A0A8V0X9H5-1", "E1BYA9-1", "A0A8V0ZXB3-1", "F1NXH3-1", "A0A1D5P5S2-1", "F1NC58-1", "A0A8V0ZA69-1", "A0A8V1A6D3-1", "F1N842-1", "A0A8V0YC26-1", "A0A8V0ZND8-1", "A0A8V0ZS02-1", "A0A8V1AKZ7-1", "A0A8V1AK42-1", "A0A8V0XYE1-1", "F1NJB8-1", "Q5F3Z7-1" ], "evidence": [ { "id": "20629", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/20629" } ] }, { "id": "47004", "name": "", "equation": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0Y3H9-1", "A0A1D5PI23-1", "P62207-1", "A0A8V0ZIN0-1", "F1P225-1", "E1BVM8-1", "A0A8V1ANF4-1", "A0A1D5P5S2-1", "P0C597-1", "P48463-1", "Q9PTJ6-1", "Q9PW71-1", "A0A8V0Z2T2-1", "A0A8V0ZYK3-1", "Q5ZJJ8-1", "Q5ZJQ7-1", "Q9YHA0-1", "F1NCC5-1", "A0A1D5PJC6-1", "E1BTX9-1", "A0A8V0XTW9-1", "A0A8V0XYX4-1", "A0A8V0XLK8-1", "A0A8V0Y1D0-1", "A0A8V0Z256-1", "A0A8V0ZE41-1", "A0A8V0ZMU4-1", "A0A8V0ZMX1-1", "A0A8V0ZQ53-1", "A0A8V0ZPJ8-1", "A0A8V0ZWA8-1", "A0A8V0ZU36-1", "E1BRQ8-1", "A0A8V1A8D0-1", "A0A8V0ZJ28-1", "A0A8V0X9H5-1", "A0A8V1AB34-1", "E1BYA9-1", "A0A8V0ZXB3-1", "A0A8V0ZFN2-1", "F1NXH3-1", "A0A8V0ZW37-1", "A0A8V0ZA69-1", "A0A8V1A6D3-1", "F1N842-1", "A0A8V0YC26-1", "A0A8V0XYE1-1", "F1NJB8-1", "A0A8V0ZND8-1", "A0A8V0ZS02-1", "A0A8V1AKZ7-1", "A0A8V1AK42-1", "Q5F3Z7-1" ], "evidence": [ { "id": "47004", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/47004" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5P5S2", "gene_name": "DUSP5", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A1D5P5S2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P5S2" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A1D5P5S2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P5S2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A1D5P5S2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P5S2" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A1D5P5S2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P5S2" } ] } ] }, { "uniprot_ac": "A0A1D5PI23", "gene_name": "DUSP3", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A1D5PI23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PI23" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A1D5PI23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PI23" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A1D5PI23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PI23" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A1D5PI23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PI23" } ] } ] }, { "uniprot_ac": "A0A1D5PJC6", "gene_name": "CPPED1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A1D5PJC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJC6" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A1D5PJC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJC6" } ] } ] }, { "uniprot_ac": "A0A8V0X9H5", "gene_name": "PPM1L", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0X9H5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X9H5" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0X9H5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X9H5" } ] } ] }, { "uniprot_ac": "A0A8V0XLK8", "gene_name": "PPEF2", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0XLK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLK8" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0XLK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLK8" } ] } ] }, { "uniprot_ac": "A0A8V0XTW9", "gene_name": "PPP3CA", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0XTW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XTW9" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0XTW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XTW9" } ] } ] }, { "uniprot_ac": "A0A8V0XYE1", "gene_name": "PHLPP2", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0XYE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XYE1" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0XYE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XYE1" } ] } ] }, { "uniprot_ac": "A0A8V0XYX4", "gene_name": "DUSP1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0XYX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XYX4" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0XYX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XYX4" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0XYX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XYX4" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0XYX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XYX4" } ] } ] }, { "uniprot_ac": "A0A8V0Y1D0", "gene_name": "CTDP1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0Y1D0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y1D0" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0Y1D0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y1D0" } ] } ] }, { "uniprot_ac": "A0A8V0Y3H9", "gene_name": "PPP2CB", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0Y3H9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3H9" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0Y3H9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3H9" } ] } ] }, { "uniprot_ac": "A0A8V0YC26", "gene_name": "DUSP19", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0YC26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC26" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0YC26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC26" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0YC26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC26" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0YC26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC26" } ] } ] }, { "uniprot_ac": "A0A8V0Z256", "gene_name": "CDKN3", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0Z256", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z256" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0Z256", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z256" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0Z256", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z256" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0Z256", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z256" } ] } ] }, { "uniprot_ac": "A0A8V0Z2T2", "gene_name": "DUSP26", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0Z2T2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2T2" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0Z2T2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2T2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0Z2T2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2T2" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0Z2T2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2T2" } ] } ] }, { "uniprot_ac": "A0A8V0ZA69", "gene_name": "PGAM5", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZA69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA69" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZA69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA69" } ] } ] }, { "uniprot_ac": "A0A8V0ZE41", "gene_name": "PPM1B", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZE41", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE41" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZE41", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE41" } ] } ] }, { "uniprot_ac": "A0A8V0ZFN2", "gene_name": "CTDSP1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZFN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFN2" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZFN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFN2" } ] } ] }, { "uniprot_ac": "A0A8V0ZIN0", "gene_name": "SSH1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZIN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIN0" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZIN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIN0" } ] } ] }, { "uniprot_ac": "A0A8V0ZJ28", "gene_name": "PTEN", "activity": [ { "ec_number": "3.1.3.67", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + phosphate.", "evidence": [ { "id": "A0A8V0ZJ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ28" } ] }, { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZJ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ28" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZJ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ28" } ] }, { "ec_number": "3.1.3.67", "activity": "", "evidence": [ { "id": "A0A8V0ZJ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ28" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0ZJ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ28" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZJ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ28" } ] } ] }, { "uniprot_ac": "A0A8V0ZMU4", "gene_name": "DUSP13", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZMU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMU4" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZMU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMU4" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZMU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMU4" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0ZMU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMU4" } ] } ] }, { "uniprot_ac": "A0A8V0ZMX1", "gene_name": "RPAP2", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZMX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMX1" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZMX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMX1" } ] } ] }, { "uniprot_ac": "A0A8V0ZND8", "gene_name": "PTPMT1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZND8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZND8" } ] }, { "ec_number": "3.1.3.27", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycero-3'-phosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + phosphate.", "evidence": [ { "id": "A0A8V0ZND8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZND8" } ] }, { "ec_number": "3.1.3.27", "activity": "", "evidence": [ { "id": "A0A8V0ZND8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZND8" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZND8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZND8" } ] } ] }, { "uniprot_ac": "A0A8V0ZPJ8", "gene_name": "LOC100857573", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZPJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPJ8" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZPJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPJ8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0ZPJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPJ8" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZPJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPJ8" } ] } ] }, { "uniprot_ac": "A0A8V0ZQ53", "gene_name": "DUSP29", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZQ53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ53" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZQ53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ53" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZQ53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ53" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0ZQ53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ53" } ] } ] }, { "uniprot_ac": "A0A8V0ZS02", "gene_name": "PPM1F", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZS02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS02" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZS02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS02" } ] } ] }, { "uniprot_ac": "A0A8V0ZU36", "gene_name": "SSH3", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZU36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU36" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZU36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU36" } ] } ] }, { "uniprot_ac": "A0A8V0ZW37", "gene_name": "CDC14A", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZW37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZW37" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0ZW37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZW37" } ] } ] }, { "uniprot_ac": "A0A8V0ZWA8", "gene_name": "PPP1CA", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZWA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWA8" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZWA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWA8" } ] } ] }, { "uniprot_ac": "A0A8V0ZXB3", "gene_name": "DUSP28", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZXB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXB3" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZXB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXB3" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZXB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXB3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0ZXB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXB3" } ] } ] }, { "uniprot_ac": "A0A8V0ZYK3", "gene_name": "PPP1CC", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZYK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYK3" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZYK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYK3" } ] } ] }, { "uniprot_ac": "A0A8V1A6D3", "gene_name": "DUSP8", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V1A6D3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6D3" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V1A6D3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6D3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V1A6D3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6D3" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V1A6D3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6D3" } ] } ] }, { "uniprot_ac": "A0A8V1A8D0", "gene_name": "PPTC7", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V1A8D0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8D0" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V1A8D0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8D0" } ] } ] }, { "uniprot_ac": "A0A8V1AB34", "gene_name": "CTDSPL", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V1AB34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB34" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V1AB34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB34" } ] } ] }, { "uniprot_ac": "A0A8V1AK42", "gene_name": "DUSP23", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V1AK42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK42" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V1AK42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK42" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V1AK42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK42" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V1AK42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK42" } ] } ] }, { "uniprot_ac": "A0A8V1AKZ7", "gene_name": "PPM1E", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V1AKZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKZ7" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V1AKZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKZ7" } ] } ] }, { "uniprot_ac": "A0A8V1ANF4", "gene_name": "SSH2", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V1ANF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANF4" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V1ANF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANF4" } ] } ] }, { "uniprot_ac": "E1BRQ8", "gene_name": "DUSP15", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "E1BRQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BRQ8" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "E1BRQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BRQ8" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "E1BRQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BRQ8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "E1BRQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BRQ8" } ] } ] }, { "uniprot_ac": "E1BTX9", "gene_name": "PPEF1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "E1BTX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BTX9" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "E1BTX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BTX9" } ] } ] }, { "uniprot_ac": "E1BVM8", "gene_name": "PPM1A", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "E1BVM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BVM8" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "E1BVM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BVM8" } ] } ] }, { "uniprot_ac": "E1BYA9", "gene_name": "ILKAP", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "E1BYA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYA9" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "E1BYA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYA9" } ] } ] }, { "uniprot_ac": "F1N842", "gene_name": "DUSP12", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1N842", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N842" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1N842", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N842" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1N842", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N842" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1N842", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N842" } ] } ] }, { "uniprot_ac": "F1NC58", "gene_name": "PDXP", "activity": [ { "ec_number": "3.1.3.74", "activity": "pyridoxal 5'-phosphate + H2O = pyridoxal + phosphate.", "evidence": [ { "id": "F1NC58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NC58" } ] }, { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = 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"field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": 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"table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZS11-1", "uniprot_ac": "A0A8V0ZS11", "uniprot_id": "A0A8V0ZS11_CHICK", "mass": { "chemical_mass": 43958.0, "monoisotopic_mass": 43958.0 }, "refseq": {}, "gene_names": [ { "name": "FAM98B", "type": "recommended", "evidence": [ { "id": "A0A8V0ZS11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS11" } ] } ], "protein_names": [ { "name": "Family with sequence similarity 98 member B", "type": "synonym", "evidence": [ { "id": "A0A8V0ZS11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS11/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZS11", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS11" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FAM98B", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS11", "locus": {} } ], "crossref": [ { "id": "A0A8V0ZS11", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZS11", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR018797", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018797", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZL91", "url": "https://www.orthodb.org/?gene=A0A8V0ZL91", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZS11", "url": "https://www.orthodb.org/?gene=A0A8V0ZS11", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31353", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31353", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31353:SF11", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31353:SF11", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10239", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10239", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZL91", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL91", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZL91-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL91-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZS11", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS11", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZS11-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS11-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRELEPGLKMECDILDALEALGYTGPLLEEGALNKAAQSGLSSPEFFDLCVWLGSQIKSLGDMEESITSADGNKDIESFQLEISGFLREMACPYSSLISGDIKDRLKGKEDCLKLLLFLSTELQALKIVHSKKSKSSHLEKHNEIHQEVQAICDALGLPNSSSSDIPPLLNNVEQKIKDILSKVQKNHVGKSLLTKPLNSDQVERLEKINDALRSEYECRRRMLMKRLDVTVQSFSWSDRAKVKTDDIARIYQPKRYALSPKSTITLAHLLAAREDLSKIIRTSSGSTRENTVCAINKVLMGRVPDRGGRPTEIEPPPPEMPPWQKRQEGGGRGGWGGGGGGGRGGWGGGGGRGGGGGGFGGGGFRGGGRGGGGFQGGRGGDYGGRGGYGGRGGYGDPYGGRGGGGYRRY", "length": 410, "header": "tr|A0A8V0ZS11-1|A0A8V0ZS11_CHICK Isoform 1 of Family with sequence similarity 98 member B OS=Gallus gallus OX=9031 GN=FAM98B PE=1 SV=1 CANONICAL=A0A8V0ZS11-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZL91-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS11/entry#A0A8V0ZL91-1", "sequence": { "sequence": "MRELEPGLKMECDILDALEALGYTGPLLEEGALNKAAQSGLSSPEFFDLCVWLGSQIKSLGDMEESITSADGNKDIESFQLEISGFLREMACPYSSLISGDIKDRLKGKEDCLKLLLFLSTELQALKIVHSKKSKSSHLEKHNEIHQEVQAICDALGLPNSSSSDIPPLLNNVEQKIKDILSKVQKNHVGKSLLTKPLNSDQVERLEKINDALRSEYECRRRMLMKRLDVTVQSFSWSDRAKVKTDDIARIYQPKRYALSPKSTITLAHLLAAREDLSKIIRTSSGSTRENTVCAINKGGRLWWQGWLWWQRRLWRSIWWKRRWRIPEILKE", "length": 332, "header": "tr|A0A8V0ZL91-1|A0A8V0ZL91_CHICK Computationally mapped isoform of Family with sequence similarity 98 member B OS=Gallus gallus OX=9031 GN=FAM98B PE=1 SV=1 CANONICAL=A0A8V0ZS11-1" }, "locus": { "chromosome": "5", "start_pos": 30210091, "end_pos": 30201490, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052660.1", "url": "https://www.ensembl.org/id/ENSGALT00010052660.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031566.1", "url": "https://www.ensembl.org/id/ENSGALP00010031566.1" } ] } }, { "isoform_ac": "A0A8V0ZS11-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS11/entry#A0A8V0ZS11-1", "sequence": { "sequence": "MRELEPGLKMECDILDALEALGYTGPLLEEGALNKAAQSGLSSPEFFDLCVWLGSQIKSLGDMEESITSADGNKDIESFQLEISGFLREMACPYSSLISGDIKDRLKGKEDCLKLLLFLSTELQALKIVHSKKSKSSHLEKHNEIHQEVQAICDALGLPNSSSSDIPPLLNNVEQKIKDILSKVQKNHVGKSLLTKPLNSDQVERLEKINDALRSEYECRRRMLMKRLDVTVQSFSWSDRAKVKTDDIARIYQPKRYALSPKSTITLAHLLAAREDLSKIIRTSSGSTRENTVCAINKVLMGRVPDRGGRPTEIEPPPPEMPPWQKRQEGGGRGGWGGGGGGGRGGWGGGGGRGGGGGGFGGGGFRGGGRGGGGFQGGRGGDYGGRGGYGGRGGYGDPYGGRGGGGYRRY", "length": 410, "header": "tr|A0A8V0ZS11-1|A0A8V0ZS11_CHICK Isoform 1 of Family with sequence similarity 98 member B OS=Gallus gallus OX=9031 GN=FAM98B PE=1 SV=1 CANONICAL=A0A8V0ZS11-1" }, "locus": { "chromosome": "5", "start_pos": 30210091, "end_pos": 30201498, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052657.1", "url": "https://www.ensembl.org/id/ENSGALT00010052657.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031563.1", "url": "https://www.ensembl.org/id/ENSGALP00010031563.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZS11", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS11" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZS11", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS11" } ], "pmid": "" }, { "name": "tRNA-splicing ligase complex", "id": "GO:0072669", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072669", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZS11", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS11" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "positive regulation of cell population proliferation", "id": "GO:0008284", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008284", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZS11", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS11" } ], "pmid": "" }, { "name": "positive regulation of gene expression", "id": "GO:0010628", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010628", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZS11", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS11" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZS11", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS11" } ], "pmid": "" }, { "name": "protein methyltransferase activity", "id": "GO:0008276", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008276", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZS11", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS11" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 160, "end_pos": 162, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 160, "end_pos": 162 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZS18-1", "uniprot_ac": "A0A8V0ZS18", "uniprot_id": "A0A8V0ZS18_CHICK", "mass": { "chemical_mass": 52708.0, "monoisotopic_mass": 52708.0 }, "refseq": {}, "gene_names": [ { "name": "ZNHIT6", "type": "recommended", "evidence": [ { "id": "A0A8V0ZS18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS18" } ] } ], "protein_names": [ { "name": "Box C/D snoRNA protein 1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZS18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS18/entry#names_and_taxonomy" } ] }, { "name": "Zinc finger HIT domain-containing protein 6", "type": "synonym", "evidence": [ { "id": "A0A8V0ZS18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS18/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Required for box C/D snoRNAs accumulation involved in snoRNA processing, snoRNA transport to the nucleolus and ribosome biogenesis.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZS18", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS18#function" }, { "database": "UniProtKB", "id": "ARBA00049598", "url": "https://www.uniprot.org/uniprotkb/ARBA00049598#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZS18", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS18" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ZNHIT6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS18", "locus": { "chromosome": "8", "start_pos": 15911147, "end_pos": 15886808, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010023210", "url": "https://www.ensembl.org/id/ENSGALG00010023210" } ] } } ], "crossref": [ { "id": "A0A8V0ZS18", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZS18", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd23023", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd23023", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR007529", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007529", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051639", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051639", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057721", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057721", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZS18", "url": "https://www.orthodb.org/?gene=A0A8V0ZS18", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13483", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13483", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13483:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13483:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04438", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04438", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25790", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25790", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZS18", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS18", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZS18-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS18-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNLAGTRTGSTVPRRQKQCAEPLHLSLSPLFFVVKSPQPKHRGSVVLQEGWKGEEVRRLGRAPGSAGREGERSAARGRRRPGNATAGPAPRGPRRAARGGGAAQPWRGRAAARARSARPAGGRWPCRGAGAGGVRDGGPQGAPRVAARGPGNASAGIRGKRGRRRERLRPALLGVGRAAACHVRQLVSPLVPRHGPAWQPLPQEPLSASFRCETCGEEEAKYRCPRCMKYSCSLLCVKKHKLALSCSGVRDKTAFVSVTEFTDLNLLSDYRFLEDVGRAADAAARDLSVHRPINYLRNRARRHNINLKTLPIGFTKRKENSTIFNKKEQKFYWHLKLVFPHCHAEYILKRVPEDKTLTDILKPYIDPVESDPVVCQRLKTYTMSPRSDVQILMKIENRKQNSTRYSELDASRSLLENLKNKVIIEYPTLFVVLKKLKNDMVVLGQGKHIFISCYAILRYFSWINSNQGYTHY", "length": 472, "header": "tr|A0A8V0ZS18-1|A0A8V0ZS18_CHICK Isoform 1 of Box C/D snoRNA protein 1 OS=Gallus gallus OX=9031 GN=ZNHIT6 PE=3 SV=1 CANONICAL=A0A8V0ZS18-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZS18-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS18/entry#A0A8V0ZS18-1", "sequence": { "sequence": "MNLAGTRTGSTVPRRQKQCAEPLHLSLSPLFFVVKSPQPKHRGSVVLQEGWKGEEVRRLGRAPGSAGREGERSAARGRRRPGNATAGPAPRGPRRAARGGGAAQPWRGRAAARARSARPAGGRWPCRGAGAGGVRDGGPQGAPRVAARGPGNASAGIRGKRGRRRERLRPALLGVGRAAACHVRQLVSPLVPRHGPAWQPLPQEPLSASFRCETCGEEEAKYRCPRCMKYSCSLLCVKKHKLALSCSGVRDKTAFVSVTEFTDLNLLSDYRFLEDVGRAADAAARDLSVHRPINYLRNRARRHNINLKTLPIGFTKRKENSTIFNKKEQKFYWHLKLVFPHCHAEYILKRVPEDKTLTDILKPYIDPVESDPVVCQRLKTYTMSPRSDVQILMKIENRKQNSTRYSELDASRSLLENLKNKVIIEYPTLFVVLKKLKNDMVVLGQGKHIFISCYAILRYFSWINSNQGYTHY", "length": 472, "header": "tr|A0A8V0ZS18-1|A0A8V0ZS18_CHICK Isoform 1 of Box C/D snoRNA protein 1 OS=Gallus gallus OX=9031 GN=ZNHIT6 PE=3 SV=1 CANONICAL=A0A8V0ZS18-1" }, "locus": { "chromosome": "8", "start_pos": 15911144, "end_pos": 15886808, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056592.1", "url": "https://www.ensembl.org/id/ENSGALT00010056592.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034334.1", "url": "https://www.ensembl.org/id/ENSGALP00010034334.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZS18", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS18" } ], "pmid": "" }, { "name": "pre-snoRNP complex", "id": "GO:0070761", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070761", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZS18", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS18" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZS18", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS18" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZS18", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS18" } ], "pmid": "" }, { "name": "ATPase binding", "id": "GO:0051117", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051117", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZS18", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS18" } ], "pmid": "" }, { "name": "TFIID-class transcription factor complex binding", "id": "GO:0001094", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001094", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZS18", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS18" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "protein complex oligomerization", "id": "GO:0051259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051259", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZS18", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS18" } ], "pmid": "" }, { "name": "box C/D snoRNP assembly", "id": "GO:0000492", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000492", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZS18", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS18" } ], "pmid": "" }, { "name": "snoRNA localization", "id": "GO:0048254", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048254", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZS18", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS18" } ], "pmid": "" }, { "name": "maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "id": "GO:0000463", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000463", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZS18", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS18" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 152, "end_pos": 154, "annotation": "n_glycosylation_sequon" }, { "start_pos": 320, "end_pos": 322, "annotation": "n_glycosylation_sequon" }, { "start_pos": 401, "end_pos": 403, "annotation": "n_glycosylation_sequon" }, { "start_pos": 83, "end_pos": 85, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZS18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS18" }, { "id": "PS51083", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51083" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "HIT-type", "eco_id": "ECO_0000259", "start_pos": 212, "end_pos": 246, "start_aa": "Cys", "end_aa": "Cys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], 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transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZS31", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS31" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZS31", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS31" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZS31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS31" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 16, "end_pos": 45, "start_aa": "His", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZS46-1", "uniprot_ac": "A0A8V0ZS46", "uniprot_id": "A0A8V0ZS46_CHICK", "mass": { "chemical_mass": 265201.0, "monoisotopic_mass": 265201.0 }, "refseq": {}, "gene_names": [ { "name": "MPRIP", "type": "recommended", "evidence": [ { "id": "A0A8V0ZS46", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS46" } ] } ], "protein_names": [ { "name": "Myosin phosphatase Rho-interacting protein", "type": "recommended", "evidence": [ { "id": "A0A8V0ZS46", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS46/entry#names_and_taxonomy" } ] }, { "name": "Rho-interacting protein 3", "type": "synonym", "evidence": [ { "id": "A0A8V0ZS46", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS46/entry#names_and_taxonomy" } ] }, { "name": "p116Rip", "type": "synonym", "evidence": [ { "id": "A0A8V0ZS46", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS46/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Targets myosin phosphatase to the actin cytoskeleton. Required for the regulation of the actin cytoskeleton by RhoA and ROCK1. Depletion leads to an increased number of stress fibers in smooth muscle cells through stabilization of actin fibers by phosphorylated myosin. Overexpression of MRIP as well as its F-actin-binding region leads to disassembly of stress fibers in neuronal cells.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJP6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJP6#function" }, { "database": "UniProtKB", "id": "ARBA00057680", "url": "https://www.uniprot.org/uniprotkb/ARBA00057680#function" }, { "database": "UniProtKB", "id": "A0A8V0ZS46", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS46#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZS46", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS46" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MPRIP", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS46", "locus": { "chromosome": "14", "start_pos": 4728279, "end_pos": 4666714, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021689", "url": "https://www.ensembl.org/id/ENSGALG00010021689" } ] } } ], "crossref": [ { "id": "cd01236", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01236", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd13275", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13275", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039597", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039597", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052223", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052223", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZJP6", "url": "https://www.orthodb.org/?gene=A0A8V0ZJP6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZLK7", "url": "https://www.orthodb.org/?gene=A0A8V0ZLK7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZS46", "url": "https://www.orthodb.org/?gene=A0A8V0ZS46", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR17271", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR17271", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR17271:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR17271:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00169", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00169", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZJP6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJP6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJP6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJP6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLK7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLK7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLK7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLK7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZS46", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS46", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZS46-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS46-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAKDNPCRKFQANIFNKSKCQNCFKPRESHLLNDEDLNQAKPIYGGWLLLAPEGTDFDNPVHRSRKWQRRFFILYEHGLLRYALDEMPTTLPQGTINMNQCTDVVDGESRTGQKFSLCILTPEKEHFIRAENKEIISGWLEMLIVYPRTNKQNQKKKRKVEPPTPQEPGPAKMAVTSSNIPSAEKVPTTKSTLWQEEMRGKESGDAGSSISPAQSPVQGAASSLKDPILDNKEDESSMNGDRIDCGRKTRVESGYFSLEKTKQDSKLEEQQLPPPPSPPSPSTPNNRRSQVIEKFEALDIENAEHMETSVPAGAALSSETRQGRSEKRVFPRKRDFTCEGTAMGSILDVSASPLSPHRRAKSLDRRSTESSMTPDLLNFKKGWLTKQYEDGQWKKHWFVLTDQSLRYYRDSVAEEAADLDGEIDLSTCYDVTEYPVQRNYGFQIHTKEGEFTLSAMTSGIRRNWIQTIMKHVRPTTAPDVTRKNFSLKLSVLKPSSLPEEKSKTSSTFEPSPKPSEKPDVEQTELDPEQKRSRARERRREGRSKTFDWAEFRPIQQALAQERANAADSSKSGTTAFPRDSGTADTDPGELERERARRREERRKRFEMVDTVDGAGPEETLRMEVDRILPVPADIKPQNVHVEIEQRWHQVETTPLREEKQIPIAPLHLAHAEDRDEGLAKQHLTTLLEKELEQKQKEALELLEQNRHLQDQLKVALGREQSAREGYVLQTEVAASPSGAWQRLHKVNQDLQSELEAQCQRQELINQQIQSLKRSYAEAKDVIRHHEAEIQSLQARLSNAAAELSIKEQTLAKLRSDLRSEKEKAKEQLEEWQHGEAALSSQLKASEQKLKNAEALLLEKTQELRDLEMQQALQRDHQKEVQRLQDRIAELSRQLNASEQARILMEEKLQKNYEALLESCEREKQVLIRSLKEVEDRANEYENQLQNSEQQMEILQKEKLSAKFEGSELVHQLEEQLLLKEASIQKLGEHIKELERERDQIKCRFHELMNQVAESDNEVARLQAKLKMEETNYHNLEQSFEEVSDQFQGVQKVLKEKEEELRHVKEMHLRIVEKKDQDLSEALVKMVALDSSLEETKVRLKAKEEALRKLTSVGAGPCAEEAEDVGSHLEVDESHPSQLGQPLPTHDALPALTYALKEEEEEVLETSQRQAEEFGSPSKAAELQDQELAQKALAKPEVGIMGAKRQRIRFSSIQCQKYIHPDGSEKNWTSSTSSDTSQDRSLSEESMSSEPAPGYPSSAASDSETYLSIIHSLETKLYITEEKLKDVTMKLESQHGHNQETLIALHHQWASTESQLREQLQSSLSQVSALVSQLESERQEKLKLIENHVSELGGFQVKNDQALACLEKCREQLRSLPKSDKEQESDLFLVTLSNMETTLSSAIQALGGAPVPPERQQSEGLIAGSPPSDGGVLGEGEPISEEQPAGTFGAGQLRWLSERVAFEASLISQIAESLKNAGSEIAQLLRETQGTAEVALMEPAGASHPAVDLAGVLSKKLLLEGEFWSQVEELRVHLSTREGEAEGKTEPAGLGFSPCFLSAVADATLIKAELGFVAQKMRESFHQRLKTIEEDLHNTKTALQQHKCMLEEILRAYRTPDFDRVVHQISEALEIQKDASERAQISWDGSCLQMGPCQEGAKMEEVRGLPGRGAGEALVSIQEDLAQQLKDKSNVLKEISVALLSLPPEEAVRDCQKLLKISQRLSYLPCMGDLERYSSLLVQDAIVQAQVCYAACKVRLEYERELKSYKESLQSMDALCQERVKTVSLLRDEYEELLRKQQGEYGEVIAVLERENADLKAKVSQLEGQRRLLEEEEHKHSKTLSELQGRYEEEIRNVIEQLNRTEDALKAERTEGLNQLDAIVRDKQDMERYHLEQMQMLEDKFQAKIKELQAIHGEELQALQEHYSQNLQRLQHALDEYQQQHLDAVPAVGPGGGDGWGAGEPGGTGQGPNGDLDSMHGLRERIQELEAQMNVMRDELENKHLEGSASTLREKYQKDFENLKATCERGFAAMEETHQKKIEDLQRQHQRELEKLREEKDRLLAEETAATISAIEAMKNAHREELERELEKSQRSQISSVNADIEALRRQYLEELQSVQRELEVLSEQYSQKCLENAHLAQALEAERQALRQCQRENQELNAHNQELNNRLAAEITRLRTLLTGEGGGEAAGSPLTQGKDAYELEVLLRVKESEIQYLKQEISSLKDELQTALRDKKYASDKYKDIYTELSIVKAKADCDISRLKEQLKAATEAQGEKSPVNTTVSGYDIMKSKSNPDFLKKDRSSVSRQLRNIRSKSLKEGLTVQERLKLFESRDLKNN", "length": 2337, "header": "tr|A0A8V0ZS46-1|A0A8V0ZS46_CHICK Isoform 1 of Myosin phosphatase Rho-interacting protein OS=Gallus gallus OX=9031 GN=MPRIP PE=1 SV=1 CANONICAL=A0A8V0ZS46-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZJP6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS46/entry#A0A8V0ZJP6-1", "sequence": { "sequence": "MAAKDNPCRKFQANIFNKSKCQNCFKPRESHLLNDEDLNQAKPIYGGWLLLAPEGTDFDNPVHRSRKWQRRFFILYEHGLLRYALDEMPTTLPQGTINMNQCTDVVDGESRTGQKFSLCILTPEKEHFIRAENKEIISGWLEMLIVYPRTNKQNQKKKRKVEPPTPQEPGPAKMAVTSSNIPSAEKVPTTKSTLWQEEMRGKESGDAGSSISPAQSPVQGAASSLKDPILDNKEDESSMNGDRIDCGRKTRVESGYFSLEKTKQDSKLEEQQLPPPPSPPSPSTPNNRYSYPKSPSQEHAQPFPSPGTRSGDRVIHSFSLNSLDSKSSCPMHKDSSRDVGRGAEKSGRPLSFKASRQYTTLADVPKAVRISNREAFQVERKRLERRTRARSPGREEVARLFGNERRRSQVIEKFEALDIENAEHMETSVPAGAALSSETRQGRSEKRVFPRKRDFTCEGTAMGSILDVSASPLSPHRRAKSLDRRSTESSMTPDLLNFKKGWLTKQYEDGQWKKHWFVLTDQSLRYYRDSVAEEAADLDGEIDLSTCYDVTEYPVQRNYGFQIHTKEGEFTLSAMTSGIRRNWIQTIMKHVRPTTAPDVTSSLPEEKSKTSSTFEPSPKPSEKPDVEQTELDPEQKRSRARERRREGRSKTFDWAEFRPIQQALAQERANAADSSKSGTTAFPRDSGTADTDPGELERERARRREERRKRFEMVDTVDGAGPEETLRMEVDRILPVPADIKPQNVHVEIEQRWHQVETTPLREEKQIPIAPLHLAHAEDRDEGLAKQHLTTLLEKELEQKQKEALELLEQNRHLQDQLKVALGREQSAREGYVLQATCERGFAAMEETHQKKIEDLQRQHQRELEKLREEKDRLLAEETAATISAIEAMKNAHREELERELEKSQRSQISSVNADIEALRRQYLEELQSVQRELEVLSEQYSQKCLENAHLAQALEAERQALRQCQRENQELNAHNQELNNRLAAEITRLRTLLTGEGGGEAAGSPLTQGKDAYELEVLLRVKESEIQYLKQEISSLKDELQTALRDKKYASDKYKDIYTELSIVKAKADCDISRLKEQLKAATEAQGEKSPVNTTVSGYDIMKSKSNPDFLKKDRSSVSRQLRNIRSKVSSQLFPCDAGGQHYSLVGI", "length": 1149, "header": "tr|A0A8V0ZJP6-1|A0A8V0ZJP6_CHICK Computationally mapped isoform of Myosin phosphatase Rho-interacting protein OS=Gallus gallus OX=9031 GN=MPRIP PE=1 SV=1 CANONICAL=A0A8V0ZS46-1" }, "locus": { "chromosome": "14", "start_pos": 4724047, "end_pos": 4670385, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052694.1", "url": "https://www.ensembl.org/id/ENSGALT00010052694.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031600.1", "url": "https://www.ensembl.org/id/ENSGALP00010031600.1" } ] } }, { "isoform_ac": "A0A8V0ZLK7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS46/entry#A0A8V0ZLK7-1", "sequence": { "sequence": "MKGPTLGITEQAKPIYGGWLLLAPEGTDFDNPVHRSRKWQRRFFILYEHGLLRYALDEMPTTLPQGTINMNQCTDVVDGESRTGQKFSLCILTPEKEHFIRAENKEIISGWLEMLIVYPRTNKQNQKKKRKVEPPTPQEPGPAKMAVTSSNIPSAEKVPTTKSTLWQEEMRGKESGDAGSSISPAQSPVQGAASSLKDPILDNKEDESSMNGDRIDCGRKTRVESGYFSLEKTKQDSKLEEQQLPPPPSPPSPSTPNNRYSYPKSPSQEHAQPFPSPGTRSGDRVIHSFSLNSLDSKSSCPMHKDSSRDVGRGAEKSGRPLSFKASRQYTTLADVPKAVRISNREAFQVERKRLERRTRARSPGREEVARLFGNERRRSQVIEKFEALDIENAEHMETSVPAGAALSSETRQGRSEKRVFPRKRDFTCEGTAMGSILDVSASPLSPHRRAKSLDRRSTESSMTPDLLNFKKGWLTKQYEDGQWKKHWFVLTDQSLRYYRDSVAEEAADLDGEIDLSTCYDVTEYPVQRNYGFQIHTKEGEFTLSAMTSGIRRNWIQTIMKHVRPTTAPDVTSSLPEEKSKTSSTFEPSPKPSEKPDVEQTELDPEQKRSRARERRREGRSKTFDWAEFRPIQQALAQERANAADSSKSGTTAFPRDSGTADTDPGELERERARRREERRKRFEMVDTVDGAGPEETLRMEVDRILPVPADIKPQNVHVEIEQRWHQVETTPLREEKQIPIAPLHLAHAEDRDEGLAKQHLTTLLEKELEQKQKEALELLEQNRHLQDQLKVALGREQSAREGYVLQATCERGFAAMEETHQKKIEDLQRQHQRELEKLREEKDRLLAEETAATISAIEAMKNAHREELERELEKSQRSQISSVNADIEALRRQYLEELQSVQRELEVLSEQYSQKCLENAHLAQALEAERQALRQCQRENQELNAHNQELNNRLAAEITRLRTLLTGEGGGEAAGSPLTQGKDAYELEVLLRVKESEIQYLKQEISSLKDELQTALRDKKYASDKYKDIYTELSIVKAKADCDISRLKEQLKAATEAQGEKSPVNTTVSGYDIMKSKSNPDFLKKDRSSVSRQLRNIRSKSVIEQVSWDN", "length": 1110, "header": "tr|A0A8V0ZLK7-1|A0A8V0ZLK7_CHICK Computationally mapped isoform of Myosin phosphatase Rho interacting protein OS=Gallus gallus OX=9031 GN=MPRIP PE=1 SV=1 CANONICAL=A0A8V0ZS46-1" }, "locus": { "chromosome": "14", "start_pos": 4725133, "end_pos": 4666757, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052705.1", "url": "https://www.ensembl.org/id/ENSGALT00010052705.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031611.1", "url": "https://www.ensembl.org/id/ENSGALP00010031611.1" } ] } }, { "isoform_ac": "A0A8V0ZS46-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS46/entry#A0A8V0ZS46-1", "sequence": { "sequence": 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"pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "actin filament binding", "id": "GO:0051015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051015", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZS46", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS46" } ], "pmid": "" }, { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZS46", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS46" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1227, "end_pos": 1229, "annotation": "n_glycosylation_sequon" }, { "start_pos": 17, "end_pos": 19, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1859, "end_pos": 1861, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2279, "end_pos": 2281, "annotation": "n_glycosylation_sequon" }, { "start_pos": 485, "end_pos": 487, "annotation": "n_glycosylation_sequon" }, { "start_pos": 896, "end_pos": 898, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZS46", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS46" }, { "id": "PS50003", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50003" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PH", "eco_id": "ECO_0000259", "start_pos": 42, "end_pos": 149, "start_aa": "Lys", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZS51-1", "uniprot_ac": "A0A8V0ZS51", "uniprot_id": "A0A8V0ZS51_CHICK", "mass": { "chemical_mass": 23262.0, "monoisotopic_mass": 23262.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "RFX-type winged-helix domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8V0ZS51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS51/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZS51", "url": 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"url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12619", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12619:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12619:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02257", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02257", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18326", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18326", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZS51", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS51", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZS51-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS51-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKSLERAVGHTHPLLSGRPSCVVCWSSASSAWEEKQLSQPGTVVVVEFLGQQVWEPIWSAGIFTSKTVQSKVDCILQEVEKFTDLEKLYLYLQLPSGPNNGDKSDQISMSSSRAQQMHAFSWIRNTLEEHPETSLPKQEVYDEYKSYCDNLGYHPLSAADFGKIMKNVFPNMKARRLGTRGKSKYPLLEHFSVTSALLWRTSAIMA", "length": 206, "header": "tr|A0A8V0ZS51-1|A0A8V0ZS51_CHICK Isoform 1 of RFX-type winged-helix domain-containing protein OS=Gallus gallus OX=9031 GN= PE=3 SV=2 CANONICAL=A0A8V0ZS51-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZS51-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS51/entry#A0A8V0ZS51-1", "sequence": { "sequence": "MKSLERAVGHTHPLLSGRPSCVVCWSSASSAWEEKQLSQPGTVVVVEFLGQQVWEPIWSAGIFTSKTVQSKVDCILQEVEKFTDLEKLYLYLQLPSGPNNGDKSDQISMSSSRAQQMHAFSWIRNTLEEHPETSLPKQEVYDEYKSYCDNLGYHPLSAADFGKIMKNVFPNMKARRLGTRGKSKYPLLEHFSVTSALLWRTSAIMA", "length": 206, "header": "tr|A0A8V0ZS51-1|A0A8V0ZS51_CHICK Isoform 1 of RFX-type winged-helix domain-containing protein OS=Gallus gallus OX=9031 GN= PE=3 SV=2 CANONICAL=A0A8V0ZS51-1" }, "locus": { "chromosome": "10", "start_pos": 7768874, "end_pos": 7736538, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056627.1", "url": "https://www.ensembl.org/id/ENSGALT00010056627.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034369.1", "url": "https://www.ensembl.org/id/ENSGALP00010034369.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZS51", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS51" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZS51", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS51" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZS51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS51" }, { "id": "PS51526", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51526" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RFX-type winged-helix", "eco_id": "ECO_0000259", "start_pos": 119, "end_pos": 206, "start_aa": "Ala", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, 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"http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47219", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47219:SF20", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47219:SF20", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00169", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00169", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00566", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00566", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015134420", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015134420", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZS67", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS67", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZS67-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS67-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZXC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXC2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZXC2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXC2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPAAGSEGDEGPAGEQAGPGAPKLCGYLQKLSGKGPLRGFRSRWFVFDPRRCYLYYFKGPQEALPLGHIDIASACFSYHQPETAAAAAGDEAAAFEVHGPGGAVAVLKAATRQDMTYWLQELQQKRWEYCNNLDAAKRDSRTSPTPSDFSKGLVAKDSPDLSILSQNASAERARNILAVETSPTDLVGEQAASQPAPVQPSAINFSLKQWSTEFKNSMSSLRKGNNENRRSVFYTSEEWELLDATPKDLEDSMALEEKRKHLAEGNKGLTSSAFPFDFGRIPQKTRRPLKDMIGSSKNRNSSDSSPTEWYSGNGNKLVSELQLKYQSQQEELEKLKKDLLSQKELVRLLQQTVRSSQYDKYFASRLCEGVPKDKLELLHQKDDQILGLNNQLEKLNLEKDSLQQEVKNLKCKVGELNEQLGMLMETIQAKDEVIMKLSRQLSECEDNSSSPSGSVNSPVATCVNKELQELDRLKDSLQGYKTQNKFLNKEILELSALRRNAEAREREWQAKYTSLEAKLCQIESKYLILLQEVRTPVCSEEQSPAREVITQLLEDALKAETSEQPEQAFFKPHLVSEYDIYGFQTVPEDDEEEKLVAKSRALDLRSLSLSENREISTGVKWENYLASTVNREMMRCAELKNLIRSGIPHEHRSKVWKWCVNLHVKKFKDTTVPEYFQTLLQSALEKQNPASKQIELDLLRTLPNNKHYSSPTSEGIQKLRNVLLAFSWRNPDIGYCQGLNRLVAIALLYLEQEDAFWCLVTIVEVFMPRDYYTKTLLGSQVDQRVFKDLMSEKLPRLHAHFEQYKVDYTLITFNWFLVVFVDSVVSDILFKIWDSFLYEGPKVIFRFALAFFKYKEEEILKLQDSMSIFKYLRYFTRTVVDARKLTGIAFGDLNPFPLRQIRNRRTYHLEKVRLELNELEAIREDFLRERETCVEKRDLISDDEEDS", "length": 947, "header": "tr|A0A8V0ZS67-1|A0A8V0ZS67_CHICK Isoform 1 of TBC1 domain family member 2B OS=Gallus gallus OX=9031 GN=TBC1D2B PE=1 SV=1 CANONICAL=A0A8V0ZS67-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZS67-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS67/entry#A0A8V0ZS67-1", "sequence": { "sequence": "MPAAGSEGDEGPAGEQAGPGAPKLCGYLQKLSGKGPLRGFRSRWFVFDPRRCYLYYFKGPQEALPLGHIDIASACFSYHQPETAAAAAGDEAAAFEVHGPGGAVAVLKAATRQDMTYWLQELQQKRWEYCNNLDAAKRDSRTSPTPSDFSKGLVAKDSPDLSILSQNASAERARNILAVETSPTDLVGEQAASQPAPVQPSAINFSLKQWSTEFKNSMSSLRKGNNENRRSVFYTSEEWELLDATPKDLEDSMALEEKRKHLAEGNKGLTSSAFPFDFGRIPQKTRRPLKDMIGSSKNRNSSDSSPTEWYSGNGNKLVSELQLKYQSQQEELEKLKKDLLSQKELVRLLQQTVRSSQYDKYFASRLCEGVPKDKLELLHQKDDQILGLNNQLEKLNLEKDSLQQEVKNLKCKVGELNEQLGMLMETIQAKDEVIMKLSRQLSECEDNSSSPSGSVNSPVATCVNKELQELDRLKDSLQGYKTQNKFLNKEILELSALRRNAEAREREWQAKYTSLEAKLCQIESKYLILLQEVRTPVCSEEQSPAREVITQLLEDALKAETSEQPEQAFFKPHLVSEYDIYGFQTVPEDDEEEKLVAKSRALDLRSLSLSENREISTGVKWENYLASTVNREMMRCAELKNLIRSGIPHEHRSKVWKWCVNLHVKKFKDTTVPEYFQTLLQSALEKQNPASKQIELDLLRTLPNNKHYSSPTSEGIQKLRNVLLAFSWRNPDIGYCQGLNRLVAIALLYLEQEDAFWCLVTIVEVFMPRDYYTKTLLGSQVDQRVFKDLMSEKLPRLHAHFEQYKVDYTLITFNWFLVVFVDSVVSDILFKIWDSFLYEGPKVIFRFALAFFKYKEEEILKLQDSMSIFKYLRYFTRTVVDARKLTGIAFGDLNPFPLRQIRNRRTYHLEKVRLELNELEAIREDFLRERETCVEKRDLISDDEEDS", "length": 947, "header": "tr|A0A8V0ZS67-1|A0A8V0ZS67_CHICK Isoform 1 of TBC1 domain family member 2B OS=Gallus gallus OX=9031 GN=TBC1D2B PE=1 SV=1 CANONICAL=A0A8V0ZS67-1" }, "locus": { "chromosome": "10", "start_pos": 3884049, "end_pos": 3857404, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010059495.1", "url": "https://www.ensembl.org/id/ENSGALT00010059495.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036326.1", "url": "https://www.ensembl.org/id/ENSGALP00010036326.1" } ] } }, { "isoform_ac": "A0A8V0ZXC2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS67/entry#A0A8V0ZXC2-1", "sequence": { "sequence": "MPAAGSEGDEGPAGEQAGPGAPKLCGYLQKLSGKGPLRGFRSRWFVFDPRRCYLYYFKGPQEALPLGHIDIASACFSYHQPETAAAAAGDEAAAFEVHGPGGAVAVLKAATRQDMTYWLQELQQKRWEYCNNLDAAKRDSRTSPTPSDFSKGLVAKDSPDLSILSQNASAERARNILAVETSPTDLVGEQAASQPAPVQPSAINFSLKQWSTEFKYSLRKSS", "length": 222, "header": "tr|A0A8V0ZXC2-1|A0A8V0ZS67_CHICK Computationally mapped isoform of TBC1 domain family member 2B OS=Gallus gallus OX=9031 GN=TBC1D2B PE=1 SV=1 CANONICAL=A0A8V0ZS67-1" }, "locus": { "chromosome": "10", "start_pos": 3868619, "end_pos": 3857404, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010059492.1", "url": "https://www.ensembl.org/id/ENSGALT00010059492.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036323.1", "url": "https://www.ensembl.org/id/ENSGALP00010036323.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 145, "start_aa": "Thr", "end_pos": 145, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr145", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:415364", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415364", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6ALB6-1", "protein_name": "TBC1 domain family, member 2B", "gene_name": "Tbc1d2b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPGAGAGAEESCSGGEGVVPGTGSEAGAVAGREPSRLCGYLQKLSGKGPLRGYRSRWFVFDSRRCYLYYFKSPQDALPLGHLDIADACFSYQGRDEAAEPGADPPTHFQVHSAGVVTVLKAPNRELMTYWLQELQQKRWEYCNSLDMVKWDSRTSPTPGDFPKGLVARDNTDIISQHPNPSAEKARTVLAVEAAPGELVGDRAAHHPAPGHPNSINFYSLKQWGNEIKNSMSSFRPGRGHSESRRTVFYTNEEWELLDPPPKDLEESLAQEDRKKPVPEGSKGVTSSGFPFEFGRNPYKGKRPLKDIIGSYKNRHSSSDPLIEGTSSGSSGGLAKPVPEMQLQIQSQQEELEQLKKDLSSQKELVQLLQQTVRSSQYDKYFMSHQISQGVPRDTLELLHQKDEQILGLSGQLERFGLEKESLQQEVRTLKSKVGELNERLGMLMETIQAKDEVIIKLSECEGSVSSPTMGPSSPLATPASRDQLELDRLKDSLQGYKSQNKFLNKEILELSALRRNAERRERDLMAKYSSLEAKLCQVESKYLILLQEMKTPVCSEEQGPARDVIAQLLEDALQVESQEQPEQAFVKPHLVSEFDIYGFRTVPDDDEEEKLVAKVRALDLKTLYLTENQEVSTGVKWENYFASTMNREMVCSPELKNLIRAGIPHEHRSKVWKWCVDRHTRKFKDSMEPGYFQALLQKALEKQNPASKQIELDLLRTLPNNKHYSSPTSEGIQKLRNVLLAFSWRNPDIGYCQGLNRLVAVALLYLEQEDAFWCLVTIVEVFMPRDYYTKTLLGSQVDQRVFRDLLSEKLPRLHTHFEQYKVDYTLITFNWFLVVFVDSVVSDILFKIWDSFLYEGPKVIFRFALALFKYKEEEILKLQDSMSIFKYLRYFTRTILDARKLTSISFGDLNPFPLRQIRNRRAYHLEKVRLELTELEAIREDFLRERDTSPDKGELVSDEEEDT", "length": 963 }, "evidence": [ { "id": "A0A8V0ZS67", "url": "https://omabrowser.org/oma/group/A0A8V0ZS67/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q3U0J8-1", "protein_name": "TBC1 domain family member 2B", "gene_name": "Tbc1d2b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPGAGDGVEESCSGGEGAVPGTGSEAGAVAGREPSRLCGYLQKLSGKGPLRGYRSRWFVFDSRRCYLYYFKSPQDALPLGHLDIADACFSYQGRDEAAEPGADPPTHFQVHSAGAVTVLKAPNRELMTYWLQELQQKRWEYCNSLDMMKWDSRTSPTPGDFPKGLVARDTTDIISQHPNPSAEKARTVLAVEAAPGELVGDRAAHQPAPGHPNPINFYSLKQWGNELKNSMSSFRPGRGHSESRRTVFYTNEEWELLDPPPKDLEESLVPEERKKPMPEGSKGVASSGFPFEFGRNPYKGKRPLKDIIGSYKNRHSSSDPLLEGTATSSGSSGGPTKPVPEMQLQIQSQQEELEQLKKDLSSQKELIRLLQQTVRSSQYDKYFTNPQISQGVPGDTLELLHQKDEQILGLSGQLERFGLEKESLQQEVRTLKSKVGELNERLGMLMETIQAKDEVIIKLSACEGSVSSPTLGPSSPLAIPASKDQLELDRLKDSLQGYKSQNKFLNKEILELSALRRNAERRERDLMAKYSSLEAKLCQVESKYLILLQEMKTPVCSEEQGPARDVIAQLLEDALQVESQEQPEQAFVKPHLVSEFDIYGFRTVPDDDEEEKLVAKVRALDLKTLYLTDNQEVSTGVKWENYFASTMNREMACSPELKNLIRAGIPHEHRSKVWKWCVDRHTRKFKDSMEPDYFQTLLQKALEKQNPASKQIELDLLRTLPNNKHYSSPTSEGIQKLRSVLLAFSWRNPDIGYCQGLNRLVAVALLYLDQEDAFWCLVTIVEVFMPRDYYTKTLLGSQVDQRVFRDLLSEKLPRLHTHFEQYKVDYTLITFNWFLVVFVDSVVSDILFKIWDSFLYEGPKVIFRFALALFKYKEEEILKLQDSMSIFKYLRYFTRTILDARKLISISFGDLNPFPLRQIRNRRAYHLEKVRLELTELEAIREDFLRERDTSPDKGELVSDEEEDT", "length": 965 }, "evidence": [ { "id": "A0A8V0ZS67", "url": "https://omabrowser.org/oma/group/A0A8V0ZS67/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9UPU7-1", "protein_name": "TBC1 domain family member 2B", "gene_name": "TBC1D2B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPGAGARAEEGGGGGEGAAQGAAAEPGAGPAREPARLCGYLQKLSGKGPLRGYRSRWFVFDARRCYLYYFKSPQDALPLGHLDIADACFSYQGPDEAAEPGTEPPAHFQVHSAGAVTVLKAPNRQLMTYWLQELQQKRWEYCNSLDMVKWDSRTSPTPGDFPKGLVARDNTDLIYPHPNASAEKARNVLAVETVPGELVGEQAANQPAPGHPNSINFYSLKQWGNELKNSMSSFRPGRGHNDSRRTVFYTNEEWELLDPTPKDLEESIVQEEKKKLTPEGNKGVTGSGFPFDFGRNPYKGKRPLKDIIGSYKNRHSSGDPSSEGTSGSGSVSIRKPASEMQLQVQSQQEELEQLKKDLSSQKELVRLLQQTVRSSQYDKYFTSSRLCEGVPKDTLELLHQKDDQILGLTSQLERFSLEKESLQQEVRTLKSKVGELNEQLGMLMETIQAKDEVIIKLSEGEGNGPPPTVAPSSPSVVPVARDQLELDRLKDNLQGYKTQNKFLNKEILELSALRRNAERRERDLMAKYSSLEAKLCQIESKYLILLQEMKTPVCSEDQGPTREVIAQLLEDALQVESQEQPEQAFVKPHLVSEYDIYGFRTVPEDDEEEKLVAKVRALDLKTLYLTENQEVSTGVKWENYFASTVNREMMCSPELKNLIRAGIPHEHRSKVWKWCVDRHTRKFKDNTEPGHFQTLLQKALEKQNPASKQIELDLLRTLPNNKHYSCPTSEGIQKLRNVLLAFSWRNPDIGYCQGLNRLVAVALLYLEQEDAFWCLVTIVEVFMPRDYYTKTLLGSQVDQRVFRDLMSEKLPRLHGHFEQYKVDYTLITFNWFLVVFVDSVVSDILFKIWDSFLYEGPKVIFRFALALFKYKEEEILKLQDSMSIFKYLRYFTRTILDARKLISISFGDLNPFPLRQIRNRRAYHLEKVRLELTELEAIREDFLRERDTSPDKGELVSDEEEDT", "length": 963 }, "evidence": [ { "id": "A0A8V0ZS67", "url": "https://omabrowser.org/oma/group/A0A8V0ZS67/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZS67", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS67" } ], "pmid": "" }, { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZS67", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS67" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "early endosome", "id": "GO:0005769", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005769", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZS67", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS67" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZS67", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS67" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "endocytosis", "id": "GO:0006897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006897", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZS67", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS67" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 167, "end_pos": 169, "annotation": "n_glycosylation_sequon" }, { "start_pos": 204, "end_pos": 206, "annotation": "n_glycosylation_sequon" }, { "start_pos": 300, "end_pos": 302, "annotation": "n_glycosylation_sequon" }, { "start_pos": 447, "end_pos": 449, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZS67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS67" }, { "id": "PS50003", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50003" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PH", "eco_id": "ECO_0000259", "start_pos": 21, "end_pos": 127, "start_aa": "Ala", "end_aa": "Trp", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZS67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS67" }, { "id": "PS50086", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50086" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Rab-GAP TBC", "eco_id": "ECO_0000259", "start_pos": 646, "end_pos": 840, "start_aa": "Gly", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 145 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 167, "end_pos": 169 }, { "start_pos": 204, "end_pos": 206 }, { "start_pos": 300, "end_pos": 302 }, { "start_pos": 447, "end_pos": 449 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZS78-1", "uniprot_ac": "A0A8V0ZS78", "uniprot_id": "A0A8V0ZS78_CHICK", "mass": { "chemical_mass": 56143.0, "monoisotopic_mass": 56143.0 }, "refseq": { "ac": "XP_004938132", "name": "potassium voltage-gated channel subfamily A member 1 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004938132" }, "gene_names": [ { "name": "KCNA1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZS78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS78" } ] }, { "name": "KCNA1", "type": "synonym", "evidence": [ { "id": "XP_004938132", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004938132" } ] } ], "protein_names": [ { "name": "Potassium voltage-gated channel subfamily A member 1", "type": "synonym", "evidence": [ { "id": "A0A8V0ZS78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS78/entry#names_and_taxonomy" } ] }, { "name": "potassium voltage-gated channel subfamily A member 1 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_004938132", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004938132" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004938132", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004938132" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZS78", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS78" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "KCNA1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS78", "locus": { "chromosome": "1", "start_pos": 74027870, "end_pos": 73911818, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010024400", "url": "https://www.ensembl.org/id/ENSGALG00010024400" } ] } } ], "crossref": [ { "id": "428101", "url": "https://www.ncbi.nlm.nih.gov/gene/428101", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003131", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003131", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003968", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003968", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003972", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003972", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004048", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004048", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005821", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005821", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027359", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027359", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028325", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028325", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PQEGSYP", "url": "https://omabrowser.org/oma/group/PQEGSYP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZS78", "url": "https://www.orthodb.org/?gene=A0A8V0ZS78", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11537", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11537", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11537:SF24", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11537:SF24", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00520", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00520", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02214", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02214", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-1296072", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1296072", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_004938132", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004938132", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZS78", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS78", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZS78-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS78-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTVMAGENMDETSVLPGHPQDSYQPAAHDDHECCERVVINIAGLRFETQLKTLAQFPNTLLGNPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDMFSEEIKFYELGEEAMEKFREDEGFIKDEERPLPEGEYQRQVWLLFEYPESSGPARVIAIVSVMVILISIVIFCLETLPELKEDKEYTVHRTDNTTQVYKSNIFTDPFFVVETLCIIWFSFELVVRFFACPSKTEFFKNIMNFIDIVAIIPYFITLGTEMAEREGTQKGEQATSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEAEEPESHFTSIPDAFWWAVVSMTTVGYGDMYPVTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETEGEEQAQLLHVSSPNLASDSDLSRRSSSTISKSEYMEIEEDMNNSIDNFREANLRTGNCTVANQNCVNKSKLLTDV", "length": 491, "header": "tr|A0A8V0ZS78-1|A0A8V0ZS78_CHICK Isoform 1 of Potassium voltage-gated channel subfamily A member 1 OS=Gallus gallus OX=9031 GN=KCNA1 PE=4 SV=1 CANONICAL=A0A8V0ZS78-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZS78-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS78/entry#A0A8V0ZS78-1", "sequence": { "sequence": "MTVMAGENMDETSVLPGHPQDSYQPAAHDDHECCERVVINIAGLRFETQLKTLAQFPNTLLGNPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDMFSEEIKFYELGEEAMEKFREDEGFIKDEERPLPEGEYQRQVWLLFEYPESSGPARVIAIVSVMVILISIVIFCLETLPELKEDKEYTVHRTDNTTQVYKSNIFTDPFFVVETLCIIWFSFELVVRFFACPSKTEFFKNIMNFIDIVAIIPYFITLGTEMAEREGTQKGEQATSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEAEEPESHFTSIPDAFWWAVVSMTTVGYGDMYPVTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETEGEEQAQLLHVSSPNLASDSDLSRRSSSTISKSEYMEIEEDMNNSIDNFREANLRTGNCTVANQNCVNKSKLLTDV", "length": 491, "header": "tr|A0A8V0ZS78-1|A0A8V0ZS78_CHICK Isoform 1 of Potassium voltage-gated channel subfamily A member 1 OS=Gallus gallus OX=9031 GN=KCNA1 PE=4 SV=1 CANONICAL=A0A8V0ZS78-1" }, "locus": { "chromosome": "1", "start_pos": 74027870, "end_pos": 74027840, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010059510.1", "url": "https://www.ensembl.org/id/ENSGALT00010059510.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036333.1", "url": "https://www.ensembl.org/id/ENSGALP00010036333.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-1296072", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1296072", "resource": "Reactome", "description": "Voltage gated Potassium channels" } ], "orthologs": [ { "uniprot_canonical_ac": "F1SL10-1", "protein_name": "Potassium voltage-gated channel subfamily A member 1", "gene_name": "KCNA1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTVMSGENVDEASAAPGHPQDGSYPRPAEHDDHECCERVVINISGLRFETQLKTLAQFPNTLLGNPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDMFSEEIKFYELGEEAMEKFREDEGFIKEEERPLPEKEYQRQVWLLFEYPESSGPARVIAIVSVMVILISIVIFCLETLPELKDDKDFTGTVHRLDNTTVIYNSNIFTDPFFIVETLCIIWFSFELVVRFFACPSKTDFFKNIMNFIDIVAIIPYFITLGTEIAEQEGNQKGEQATSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEAEEAESHFSSIPDAFWWAVVSMTTVGYGDMYPVTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETEGEEQAQLLHVSAPNLASDSDLSRRSSSTISKSEYMEIEEDMNNSIAHFRQANIRTGNCTTANQNCVNKSKLLTDV", "length": 495 }, "evidence": [ { "id": "A0A8V0ZS78", "url": "https://omabrowser.org/oma/group/A0A8V0ZS78/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3GUL0-1", "protein_name": "Potassium voltage-gated channel subfamily A member 1", "gene_name": "Kcna1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MTVMSGENADEASAAPGHPQDGSYPRQADHDDHECCERVVINISGLRFETQLKTLAQFPNTLLGNPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDMFSEEIKFYELGEEAMEKFREDEGFIKEEERPLPEKEYQRQVWLLFEYPESSGPARVIAIVSVMVILISIVIFCLETLPELKDDKDFTGTIHRIDNTTVIYTSNIFTDPFFIVETLCIIWFSFELVVRFFACPSKTDFFKNIMNFIDIVAIIPYFITLGTEIAEQEGNQKGEQATSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEAEEAESHFSSIPDAFWWAVVSMTTVGYGDMYPVTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETEGEEQAQLLHVSSPNLASDSDLSRRSSSTISKSEYMEIEEDMNNSIAHYRQANIRTGNCTTADQNCVNKSKLLTDV", "length": 495 }, "evidence": [ { "id": "A0A8V0ZS78", "url": "https://omabrowser.org/oma/group/A0A8V0ZS78/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P10499-1", "protein_name": "Potassium voltage-gated channel subfamily A member 1", "gene_name": "Kcna1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTVMSGENADEASAAPGHPQDGSYPRQADHDDHECCERVVINISGLRFETQLKTLAQFPNTLLGNPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDMFSEEIKFYELGEEAMEKFREDEGFIKEEERPLPEKEYQRQVWLLFEYPESSGPARVIAIVSVMVILISIVIFCLETLPELKDDKDFTGTIHRIDNTTVIYTSNIFTDPFFIVETLCIIWFSFELVVRFFACPSKTDFFKNIMNFIDIVAIIPYFITLGTEIAEQEGNQKGEQATSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEAEEAESHFSSIPDAFWWAVVSMTTVGYGDMYPVTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETEGEEQAQLLHVSSPNLASDSDLSRRSSSTISKSEYMEIEEDMNNSIAHYRQANIRTGNCTATDQNCVNKSKLLTDV", "length": 495 }, "evidence": [ { "id": "A0A8V0ZS78", "url": "https://omabrowser.org/oma/group/A0A8V0ZS78/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P16388-1", "protein_name": "Potassium voltage-gated channel subfamily A member 1", "gene_name": "Kcna1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTVMSGENADEASTAPGHPQDGSYPRQADHDDHECCERVVINISGLRFETQLKTLAQFPNTLLGNPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDMFSEEIKFYELGEEAMEKFREDEGFIKEEERPLPEKEYQRQVWLLFEYPESSGPARVIAIVSVMVILISIVIFCLETLPELKDDKDFTGTIHRIDNTTVIYTSNIFTDPFFIVETLCIIWFSFELVVRFFACPSKTDFFKNIMNFIDIVAIIPYFITLGTEIAEQEGNQKGEQATSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEAEEAESHFSSIPDAFWWAVVSMTTVGYGDMYPVTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETEGEEQAQLLHVSSPNLASDSDLSRRSSSTISKSEYMEIEEDMNNSIAHYRQANIRTGNCTTADQNCVNKSKLLTDV", "length": 495 }, "evidence": [ { "id": "A0A8V0ZS78", "url": "https://omabrowser.org/oma/group/A0A8V0ZS78/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q09470-1", "protein_name": "Potassium voltage-gated channel subfamily A member 1", "gene_name": "KCNA1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTVMSGENVDEASAAPGHPQDGSYPRQADHDDHECCERVVINISGLRFETQLKTLAQFPNTLLGNPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDMFSEEIKFYELGEEAMEKFREDEGFIKEEERPLPEKEYQRQVWLLFEYPESSGPARVIAIVSVMVILISIVIFCLETLPELKDDKDFTGTVHRIDNTTVIYNSNIFTDPFFIVETLCIIWFSFELVVRFFACPSKTDFFKNIMNFIDIVAIIPYFITLGTEIAEQEGNQKGEQATSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEAEEAESHFSSIPDAFWWAVVSMTTVGYGDMYPVTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETEGEEQAQLLHVSSPNLASDSDLSRRSSSTMSKSEYMEIEEDMNNSIAHYRQVNIRTANCTTANQNCVNKSKLLTDV", "length": 495 }, "evidence": [ { "id": "A0A8V0ZS78", "url": "https://omabrowser.org/oma/group/A0A8V0ZS78/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 12, "go_terms": [ { "name": "startle response", "id": "GO:0001964", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001964", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZS78", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS78" } ], "pmid": "" }, { "name": "membrane repolarization during action potential", "id": "GO:0086011", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0086011", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZS78", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS78" } ], "pmid": "" }, { "name": "detection of mechanical stimulus involved in sensory perception of touch", "id": "GO:0050976", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050976", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZS78", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS78" } ], "pmid": "" }, { "name": "neuronal action potential", "id": "GO:0019228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019228", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZS78", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS78" } ], "pmid": "" }, { "name": "protein homooligomerization", "id": "GO:0051260", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051260", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZS78", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS78" } ], "pmid": "" }, { "name": "action potential", "id": "GO:0001508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001508", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZS78", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS78" } ], "pmid": "" }, { "name": "brain development", "id": "GO:0007420", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007420", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZS78", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS78" } ], "pmid": "" }, { "name": "detection of mechanical stimulus involved in sensory perception of pain", "id": "GO:0050966", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050966", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZS78", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS78" } ], "pmid": "" }, { "name": "magnesium ion homeostasis", "id": "GO:0010960", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010960", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZS78", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS78" } ], "pmid": "" }, { "name": "cellular response to magnesium ion", "id": "GO:0071286", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071286", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZS78", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS78" } ], "pmid": "" }, { "name": "neuroblast proliferation", "id": "GO:0007405", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007405", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZS78", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS78" } ], "pmid": "" }, { "name": "potassium ion transmembrane transport", "id": "GO:0071805", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071805", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZS78", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS78" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "delayed rectifier potassium channel activity", "id": "GO:0005251", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005251", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZS78", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS78" } ], "pmid": "" }, { "name": "disordered domain specific binding", "id": "GO:0097718", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097718", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZS78", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS78" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 11, "go_terms": [ { "name": "cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZS78", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS78" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZS78", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS78" } ], "pmid": "" }, { "name": "dendrite", "id": "GO:0030425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZS78", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS78" } ], "pmid": "" }, { "name": "neuronal cell body", "id": "GO:0043025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043025", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZS78", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS78" } ], "pmid": "" }, { "name": "perikaryon", "id": "GO:0043204", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043204", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZS78", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS78" } ], "pmid": "" }, { "name": "axon terminus", "id": "GO:0043679", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043679", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZS78", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS78" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZS78", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS78" } ], "pmid": "" }, { "name": "voltage-gated potassium channel complex", "id": "GO:0008076", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008076", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZS78", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS78" } ], "pmid": "" }, { "name": "axon initial segment", "id": "GO:0043194", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043194", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZS78", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS78" } ], "pmid": "" }, { "name": "juxtaparanode region of axon", "id": "GO:0044224", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044224", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZS78", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS78" } ], "pmid": "" }, { "name": "paranode region of axon", "id": "GO:0033270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZS78", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS78" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 203, "end_pos": 205, "annotation": "n_glycosylation_sequon" }, { "start_pos": 458, "end_pos": 460, "annotation": "n_glycosylation_sequon" }, { "start_pos": 473, "end_pos": 475, "annotation": "n_glycosylation_sequon" }, { "start_pos": 483, "end_pos": 485, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZS78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS78" }, { "id": "SM00225", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00225" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BTB", "eco_id": "ECO_0000259", "start_pos": 35, "end_pos": 135, "start_aa": "Glu", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 203, "end_pos": 205 }, { "start_pos": 458, "end_pos": 460 }, { "start_pos": 473, "end_pos": 475 }, { "start_pos": 483, "end_pos": 485 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZS84-1", "uniprot_ac": "A0A8V0ZS84", "uniprot_id": "A0A8V0ZS84_CHICK", "mass": { "chemical_mass": 69689.0, "monoisotopic_mass": 69689.0 }, "refseq": {}, "gene_names": [ { "name": "KCNC1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZS84", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS84" } ] } ], "protein_names": [ { "name": "Potassium voltage-gated channel subfamily C member 1", "type": "synonym", "evidence": [ { "id": "A0A8V0ZS84", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS84/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZS84", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS84" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "KCNC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS84", "locus": { "chromosome": "5", "start_pos": 11939434, "end_pos": 11824402, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010024401", "url": "https://www.ensembl.org/id/ENSGALG00010024401" } ] } } ], "crossref": [ { "id": "A0A8V0ZS84", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZS84", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd18414", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18414", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "423076", "url": "https://www.ncbi.nlm.nih.gov/gene/423076", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003131", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003131", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003968", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003968", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003974", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003974", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005403", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005403", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005821", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005821", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027359", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027359", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028325", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028325", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:423076", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423076", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QTQSWAL", "url": "https://omabrowser.org/oma/group/QTQSWAL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZS84", "url": "https://www.orthodb.org/?gene=A0A8V0ZS84", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZZJ4", "url": "https://www.orthodb.org/?gene=A0A8V0ZZJ4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A1E6", "url": "https://www.orthodb.org/?gene=A0A8V1A1E6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A1F1", "url": "https://www.orthodb.org/?gene=A0A8V1A1F1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A4X2", "url": "https://www.orthodb.org/?gene=A0A8V1A4X2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11537", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11537", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11537:SF87", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11537:SF87", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00520", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00520", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02214", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02214", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-1296072", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1296072", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "29463", "url": "https://www.rhea-db.org/rhea/29463", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZS84", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS84", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZS84-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS84-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZZJ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZJ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZZJ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZJ4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A1E6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1E6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A1E6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1E6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A1F1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1F1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A1F1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1F1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A4X2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4X2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A4X2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4X2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGQGDESDRIVINVGGTRHQTYRSTLRTLPGTRLAWIAEPDAHSHFDYDPRTDEFFFDRHPGVFAHILNYYRTGKLHCPADVCGPLYEEELAFWGIDETDVEPCCWMTYRQHRDAEEALDSFGGAPLDSSAEDGDIDGTGDSGDGEEELEMTKRLALSDSPDGRSGGFWRRWQPRIWALFEDPYSSRYARYVAFASLFFILVSITTFCLETHERFNPIVNKTETEFIGNDTQVRHYREAETEAFLTYIEGVCVVWFTFEFLMRVTFCPNKVEFIKNSLNIIDFVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGAKPNDPSASEHTHFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKKKKHIPRPPQLGSPNYCKSVVNSPHHSTQSDTCPLAQEEILEINRADSKLNGEVAKAALANEDCPHIDQAITPDEGLPFTRSGTRERYGPCFLLSTGEYPCPPDGGIRKGMHLHLNTEQNVGSRLCARLNVSGPLTIHEDFIIHETAAVQRRISIKDTCFLHL", "length": 618, "header": "tr|A0A8V0ZS84-1|A0A8V0ZS84_CHICK Isoform 1 of Potassium voltage-gated channel subfamily C member 1 OS=Gallus gallus OX=9031 GN=KCNC1 PE=4 SV=1 CANONICAL=A0A8V0ZS84-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZS84-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS84/entry#A0A8V0ZS84-1", "sequence": { "sequence": "MGQGDESDRIVINVGGTRHQTYRSTLRTLPGTRLAWIAEPDAHSHFDYDPRTDEFFFDRHPGVFAHILNYYRTGKLHCPADVCGPLYEEELAFWGIDETDVEPCCWMTYRQHRDAEEALDSFGGAPLDSSAEDGDIDGTGDSGDGEEELEMTKRLALSDSPDGRSGGFWRRWQPRIWALFEDPYSSRYARYVAFASLFFILVSITTFCLETHERFNPIVNKTETEFIGNDTQVRHYREAETEAFLTYIEGVCVVWFTFEFLMRVTFCPNKVEFIKNSLNIIDFVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGAKPNDPSASEHTHFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKKKKHIPRPPQLGSPNYCKSVVNSPHHSTQSDTCPLAQEEILEINRADSKLNGEVAKAALANEDCPHIDQAITPDEGLPFTRSGTRERYGPCFLLSTGEYPCPPDGGIRKGMHLHLNTEQNVGSRLCARLNVSGPLTIHEDFIIHETAAVQRRISIKDTCFLHL", "length": 618, "header": "tr|A0A8V0ZS84-1|A0A8V0ZS84_CHICK Isoform 1 of Potassium voltage-gated channel subfamily C member 1 OS=Gallus gallus OX=9031 GN=KCNC1 PE=4 SV=1 CANONICAL=A0A8V0ZS84-1" }, "locus": { "chromosome": "5", "start_pos": 11938430, "end_pos": 11824406, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010059522.1", "url": "https://www.ensembl.org/id/ENSGALT00010059522.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036343.1", "url": "https://www.ensembl.org/id/ENSGALP00010036343.1" } ] } }, { "isoform_ac": "A0A8V0ZZJ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS84/entry#A0A8V0ZZJ4-1", "sequence": { "sequence": "MGQGDESDRIVINVGGTRHQTYRSTLRTLPGTRLAWIAEPDAHSHFDYDPRTDEFFFDRHPGVFAHILNYYRTGKLHCPADVCGPLYEEELAFWGIDETDVEPCCWMTYRQHRDAEEALDSFGGAPLDSSAEDGDIDGTGDSGDGEEELEMTKRLALSDSPDGRSGGFWRRWQPRIWALFEDPYSSRYARYVAFASLFFILVSITTFCLETHERFNPIVNKTETEFIGNDTQVRHYREAETEAFLTYIEGVCVVWFTFEFLMRVTFCPNKVEFIKNSLNIIDFVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGAKPNDPSASEHTHFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKKKKHIPRPPQLGSPNYCKSVVNSPHHSTQSDTCPLAQEEILEINRAGYEMSRSLNSIAGISGKAIGLSSVSAPYSSPSPVRRSWSPIPSIL", "length": 546, "header": "tr|A0A8V0ZZJ4-1|A0A8V0ZS84_CHICK Computationally mapped isoform of Potassium voltage-gated channel subfamily C member 1 OS=Gallus gallus OX=9031 GN=KCNC1 PE=4 SV=1 CANONICAL=A0A8V0ZS84-1" }, "locus": { "chromosome": "5", "start_pos": 11922706, "end_pos": 11824406, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010059513.1", "url": "https://www.ensembl.org/id/ENSGALT00010059513.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036336.1", "url": "https://www.ensembl.org/id/ENSGALP00010036336.1" } ] } }, { "isoform_ac": "A0A8V1A1E6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS84/entry#A0A8V1A1E6-1", "sequence": { "sequence": "MGQGDESDRIVINVGGTRHQTYRSTLRTLPGTRLAWIAEPDAHSHFDYDPRTDEFFFDRHPGVFAHILNYYRTGKLHCPADVCGPLYEEELAFWGIDETDVEPCCWMTYRQHRDAEEALDSFGGAPLDSSAEDGDIDGTGDSGDGEEELEMTKRLALSDSPDGRSGGFWRRWQPRIWALFEDPYSSRYARYVAFASLFFILVSITTFCLETHERFNPIVNKTETEFIGNDTQVRHYREAETEAFLTYIEGVCVVWFTFEFLMRVTFCPNKVEFIKNSLNIIDFVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGAKPNDPSASEHTHFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKKKKHIPRPPQLGSPNYCKSVVNSPHHSTQSDTCPLAQEEILEINRADSKLNGEVAKAALANEDCPHIDQAITPDEGLPFTRSGTRERYGPCFLLSTGEYPCPPDGGIRKGYEMSRSLNSIAGISGKAIGLSSVSAPYSSPSPVRRSWSPIPSIL", "length": 609, "header": "tr|A0A8V1A1E6-1|A0A8V0ZS84_CHICK Computationally mapped isoform of Potassium voltage-gated channel subfamily C member 1 OS=Gallus gallus OX=9031 GN=KCNC1 PE=4 SV=1 CANONICAL=A0A8V0ZS84-1" }, "locus": { "chromosome": "5", "start_pos": 11922706, "end_pos": 11824406, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010059512.1", "url": "https://www.ensembl.org/id/ENSGALT00010059512.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036335.1", "url": "https://www.ensembl.org/id/ENSGALP00010036335.1" } ] } }, { "isoform_ac": "A0A8V1A1F1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS84/entry#A0A8V1A1F1-1", "sequence": { "sequence": "MGQGDESDRIVINVGGTRHQTYRSTLRTLPGTRLAWIAEPDAHSHFDYDPRTDEFFFDRHPGVFAHILNYYRTGKLHCPADVCGPLYEEELAFWGIDETDVEPCCWMTYRQHRDAEEALDSFGGAPLDSSAEDGDIDGTGDSGDGEEELEMTKRLALSDSPDGRSGGFWRRWQPRIWALFEDPYSSRYARYVAFASLFFILVSITTFCLETHERFNPIVNKTETEFIGNDTQVRHYREAETEAFLTYIEGVCVVWFTFEFLMRVTFCPNKVEFIKNSLNIIDFVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGAKPNDPSASEHTHFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKKKKHIPRPPQLGSPNYCKSVVNSPHHSTQSDTCPLAQEEILEINRAGTFCKPFRNSMALPTCCSSGDALQLKVSQTLLLPLALQ", "length": 539, "header": "tr|A0A8V1A1F1-1|A0A8V0ZS84_CHICK Computationally mapped isoform of Potassium voltage-gated channel subfamily C member 1 OS=Gallus gallus OX=9031 GN=KCNC1 PE=4 SV=1 CANONICAL=A0A8V0ZS84-1" }, "locus": { "chromosome": "5", "start_pos": 11925933, "end_pos": 11824406, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010059519.1", "url": "https://www.ensembl.org/id/ENSGALT00010059519.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036341.1", "url": "https://www.ensembl.org/id/ENSGALP00010036341.1" } ] } }, { "isoform_ac": "A0A8V1A4X2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS84/entry#A0A8V1A4X2-1", "sequence": { "sequence": "MGQGDESDRIVINVGGTRHQTYRSTLRTLPGTRLAWIAEPDAHSHFDYDPRTDEFFFDRHPGVFAHILNYYRTGKLHCPADVCGPLYEEELAFWGIDETDVEPCCWMTYRQHRDAEEALDSFGGAPLDSSAEDGDIDGTGDSGDGEEELEMTKRLALSDSPDGRSGGFWRRWQPRIWALFEDPYSSRYARYVAFASLFFILVSITTFCLETHERFNPIVNKTETEFIGNDTQVRHYREAETEAFLTYIEGVCVVWFTFEFLMRVTFCPNKVEFIKNSLNIIDFVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGAKPNDPSASEHTHFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKKKKHIPRPPQLGSPNYCKSVVNSPHHSTQSDTCPLAQEEILEINRAAGMHLHLNTEQNVGSRLCARLNVSGPLTIHEDFIIHETAAVQRRISIKDTCFLHL", "length": 556, "header": "tr|A0A8V1A4X2-1|A0A8V0ZS84_CHICK Computationally mapped isoform of Potassium voltage-gated channel subfamily C member 1 OS=Gallus gallus OX=9031 GN=KCNC1 PE=4 SV=1 CANONICAL=A0A8V0ZS84-1" }, "locus": { "chromosome": "5", "start_pos": 11938430, "end_pos": 11824406, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010059529.1", "url": "https://www.ensembl.org/id/ENSGALT00010059529.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036349.1", "url": "https://www.ensembl.org/id/ENSGALP00010036349.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:423076", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423076", "resource": "KEGG Pathway" }, { "id": "R-GGA-1296072", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1296072", "resource": "Reactome", "description": "Voltage gated Potassium channels" } ], "orthologs": [ { "uniprot_canonical_ac": "F1N553-1", "protein_name": "Potassium voltage-gated channel subfamily C member 1", "gene_name": "KCNC1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGQGDESERIVINVGGTRHQTYRSTLRTLPGTRLAWLAEPDAHSHFDYDPRADEFFFDRHPGVFAHILNYYRTGKLHCPADVCGPLYEEELAFWGIDETDVEPCCWMTYRQHRDAEEALDSFGGAPLDNSADDADADGPGDSGDGEDELEMTKRLALSDSPDGRPGGFWRRWQPRIWALFEDPYSSRYARYVAFASLFFILVSITTFCLETHERFNPIVNKTEIENVRNGTQVRYYREAETEAFLTYIEGVCVVWFTFEFLMRVVFCPNKVEFIKNSLNIIDFVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGAQPNDPSASEHTHFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKKKKHIPRPPQLGSPNYCKSVVNSPHHSTQSDTCPLAQEEILEINRADSKLNGEVAKAALANEDCPHIDQALTPDEGLPFTRSGTRERYGPCFLLSTGEYACPPGGGVRKDLCKESPVIAKYMPTEAVRVT", "length": 585 }, "evidence": [ { "id": "A0A8V0ZS84", "url": "https://omabrowser.org/oma/group/A0A8V0ZS84/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P15388-1", "protein_name": "Voltage-gated potassium channel KCNC1", "gene_name": "Kcnc1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGQGDESERIVINVGGTRHQTYRSTLRTLPGTRLAWLAEPDAHSHFDYDPRADEFFFDRHPGVFAHILNYYRTGKLHCPADVCGPLYEEELAFWGIDETDVEPCCWMTYRQHRDAEEALDSFGGAPLDNSADDADADGPGDSGDGEDELEMTKRLALSDSPDGRPGGFWRRWQPRIWALFEDPYSSRYARYVAFASLFFILVSITTFCLETHERFNPIVNKTEIENVRNGTQVRYYREAETEAFLTYIEGVCVVWFTFEFLMRVVFCPNKVEFIKNSLNIIDFVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGAQPNDPSASEHTHFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKKKKHIPRPPQLGSPNYCKSVVNSPHHSTQSDTCPLAQEEILEINRAGRKPLRGMSI", "length": 511 }, "evidence": [ { "id": "A0A8V0ZS84", "url": "https://omabrowser.org/oma/group/A0A8V0ZS84/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P17972-1", "protein_name": "Potassium voltage-gated channel protein Shaw", "gene_name": "Shaw", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MNLINMDSENRVVLNVGGIRHETYKATLKKIPATRLSRLTEALANYDPILNEYFFDRHPGVFAQVLNYYRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWMTYTQHRDTQETLAVLDRLDLDTEKPSEEELARKFGFEEDYYKGTISWWQEMKPRIWSLFDEPYSSNAAKTIGVVSVFFICISILSFCLKTHPDMRVPIVRNITVKTANGSNGWFLDKTQTNAHIAFFYIECVCNAWFTFEILVRFISSPNKWEFIKSSVNIIDYIATLSFYIDLVLQRFASHLENADILEFFSIIRIMRLFKLTRHSSGLKILIQTFRASAKELTLLVFFLVLGIVIFASLVYYAERIQPNPHNDFNSIPLGLWWALVTMTTVGYGDMAPKTYIGMFVGALCALAGVLTIALPVPVIVSNFAMYYSHTQARAKLPKKRRRVLPVEQPRQPRLPGAPGGVSGCGTPGSGPHSGPMGSGGTGPRRMNNKTKDLVSPKSDMAFSFD", "length": 498 }, "evidence": [ { "id": "A0A8V0ZS84", "url": "https://omabrowser.org/oma/group/A0A8V0ZS84/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "P25122-1", "protein_name": "Voltage-gated potassium channel KCNC1", "gene_name": "Kcnc1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGQGDESERIVINVGGTRHQTYRSTLRTLPGTRLAWLAEPDAHSHFDYDPRADEFFFDRHPGVFAHILNYYRTGKLHCPADVCGPLYEEELAFWGIDETDVEPCCWMTYRQHRDAEEALDSFGGAPLDNSADDADADGPGDSGDGEDELEMTKRLALSDSPDGRPGGFWRRWQPRIWALFEDPYSSRYARYVAFASLFFILVSITTFCLETHERFNPIVNKTEIENVRNGTQVRYYREAETEAFLTYIEGVCVVWFTFEFLMRVVFCPNKVEFIKNSLNIIDFVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGAQPNDPSASEHTHFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKKKKHIPRPPQLGSPNYCKSVVNSPHHSTQSDTCPLAQEEILEINRADSKLNGEVAKAALANEDCPHIDQALTPDEGLPFTRSGTRERYGPCFLLSTGEYACPPGGGMRKDLCKESPVIAKYMPTEAVRVT", "length": 585 }, "evidence": [ { "id": "A0A8V0ZS84", "url": "https://omabrowser.org/oma/group/A0A8V0ZS84/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P48547-1", "protein_name": "Voltage-gated potassium channel KCNC1", "gene_name": "KCNC1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGQGDESERIVINVGGTRHQTYRSTLRTLPGTRLAWLAEPDAHSHFDYDPRADEFFFDRHPGVFAHILNYYRTGKLHCPADVCGPLYEEELAFWGIDETDVEPCCWMTYRQHRDAEEALDSFGGAPLDNSADDADADGPGDSGDGEDELEMTKRLALSDSPDGRPGGFWRRWQPRIWALFEDPYSSRYARYVAFASLFFILVSITTFCLETHERFNPIVNKTEIENVRNGTQVRYYREAETEAFLTYIEGVCVVWFTFEFLMRVIFCPNKVEFIKNSLNIIDFVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGAQPNDPSASEHTHFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKKKKHIPRPPQLGSPNYCKSVVNSPHHSTQSDTCPLAQEEILEINRAGRKPLRGMSI", "length": 511 }, "evidence": [ { "id": "A0A8V0ZS84", "url": "https://omabrowser.org/oma/group/A0A8V0ZS84/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "delayed rectifier potassium channel activity", "id": "GO:0005251", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005251", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZS84", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS84" } ], "pmid": "" }, { "name": "transmembrane transporter binding", "id": "GO:0044325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044325", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZS84", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS84" } ], "pmid": "" }, { "name": "kinesin binding", "id": "GO:0019894", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019894", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZS84", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS84" } ], "pmid": "" }, { "name": "voltage-gated potassium channel activity", "id": "GO:0005249", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005249", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZS84", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS84" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "axon terminus", "id": "GO:0043679", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043679", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZS84", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS84" } ], "pmid": "" }, { "name": "postsynaptic membrane", "id": "GO:0045211", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045211", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZS84", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS84" } ], "pmid": "" }, { "name": "axolemma", "id": "GO:0030673", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030673", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZS84", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS84" } ], "pmid": "" }, { "name": "voltage-gated potassium channel complex", "id": "GO:0008076", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008076", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZS84", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS84" } ], "pmid": "" }, { "name": "neuronal cell body membrane", "id": "GO:0032809", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032809", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZS84", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS84" } ], "pmid": "" }, { "name": "presynaptic membrane", "id": "GO:0042734", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042734", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZS84", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS84" } ], "pmid": "" }, { "name": "dendrite membrane", "id": "GO:0032590", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032590", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZS84", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS84" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "protein homooligomerization", "id": "GO:0051260", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051260", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZS84", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS84" } ], "pmid": "" }, { "name": "protein tetramerization", "id": "GO:0051262", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051262", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZS84", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS84" } ], "pmid": "" }, { "name": "action potential", "id": "GO:0001508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001508", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZS84", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS84" } ], "pmid": "" }, { "name": "potassium ion transmembrane transport", "id": "GO:0071805", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071805", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZS84", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS84" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 220, "end_pos": 222, "annotation": "n_glycosylation_sequon" }, { "start_pos": 229, "end_pos": 231, "annotation": "n_glycosylation_sequon" }, { "start_pos": 585, "end_pos": 587, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "29463", "name": "", "equation": "K(+)(in) = K(+)(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "29463", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/29463" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZS84", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS84" }, { "id": "SM00225", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00225" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BTB", "eco_id": "ECO_0000259", "start_pos": 8, "end_pos": 112, "start_aa": "Asp", "end_aa": "His", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 220, "end_pos": 222 }, { "start_pos": 229, "end_pos": 231 }, { "start_pos": 585, "end_pos": 587 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZS90-1", "uniprot_ac": "A0A8V0ZS90", "uniprot_id": "A0A8V0ZS90_CHICK", "mass": { "chemical_mass": 19387.0, "monoisotopic_mass": 19387.0 }, "refseq": {}, "gene_names": [ { "name": "RBPMS2", "type": "recommended", "evidence": [ { "id": "A0A8V0ZS90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS90" } ] } ], "protein_names": [ { "name": "RNA binding protein, mRNA processing factor 2", "type": "synonym", "evidence": [ { "id": "A0A8V0ZS90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS90/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZS90", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS90" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RBPMS2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS90", "locus": { "chromosome": "10", "start_pos": 1126006, "end_pos": 1147615, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010023239", "url": "https://www.ensembl.org/id/ENSGALG00010023239" } ] } } ], "crossref": [ { "id": "A0A8V0ZS90", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZS90", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd12683", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12683", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034787", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034787", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZS90", "url": "https://www.orthodb.org/?gene=A0A8V0ZS90", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10501", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10501", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00076", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00076", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZS90", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS90", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZS90-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS90-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSNLNKDTEHTNGGGNVEEEVRTLFVSGLPVDIKPRELYLLFRPFKGYEGSLIKLTSKQPVGFVTFDSRAGAEAAKNALNGIRFDPENPQTLRLEFAKANTKMAKSKLMATPNPTNIHPALGAHFIARDPYDLTGAALIPASPEAWAPYPLYTTELTPAIPHAAFTYPAAAAAAAALHAQ", "length": 180, "header": "tr|A0A8V0ZS90-1|A0A8V0ZS90_CHICK Isoform 1 of RNA binding protein, mRNA processing factor 2 OS=Gallus gallus OX=9031 GN=RBPMS2 PE=4 SV=1 CANONICAL=A0A8V0ZS90-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZS90-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS90/entry#A0A8V0ZS90-1", "sequence": { "sequence": "MSNLNKDTEHTNGGGNVEEEVRTLFVSGLPVDIKPRELYLLFRPFKGYEGSLIKLTSKQPVGFVTFDSRAGAEAAKNALNGIRFDPENPQTLRLEFAKANTKMAKSKLMATPNPTNIHPALGAHFIARDPYDLTGAALIPASPEAWAPYPLYTTELTPAIPHAAFTYPAAAAAAAALHAQ", "length": 180, "header": "tr|A0A8V0ZS90-1|A0A8V0ZS90_CHICK Isoform 1 of RNA binding protein, mRNA processing factor 2 OS=Gallus gallus OX=9031 GN=RBPMS2 PE=4 SV=1 CANONICAL=A0A8V0ZS90-1" }, "locus": { "chromosome": "10", "start_pos": 1147412, "end_pos": 1136771, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056668.1", "url": "https://www.ensembl.org/id/ENSGALT00010056668.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034410.1", "url": "https://www.ensembl.org/id/ENSGALP00010034410.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZS90", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS90" } ], "pmid": "" }, { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZS90", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS90" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZS90", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS90" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZS90", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS90" } ], "pmid": "" }, { "name": "cytoplasmic stress granule", "id": "GO:0010494", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010494", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZS90", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS90" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "negative regulation of smooth muscle cell differentiation", "id": "GO:0051151", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051151", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZS90", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS90" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZS90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS90" }, { "id": "PS50102", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50102" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RRM", "eco_id": "ECO_0000259", "start_pos": 22, "end_pos": 99, "start_aa": "Arg", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZS98-1", "uniprot_ac": "A0A8V0ZS98", "uniprot_id": "A0A8V0ZS98_CHICK", "mass": { "chemical_mass": 78170.0, "monoisotopic_mass": 78170.0 }, "refseq": { "ac": "XP_003642870", "name": "kelch-like protein 11", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642870" }, "gene_names": [ { "name": "KLHL11", "type": "recommended", "evidence": [ { "id": "A0A8V0ZS98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS98" } ] }, { "name": "KLHL11", "type": "synonym", "evidence": [ { "id": "XP_003642870", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642870" } ] } ], "protein_names": [ { "name": "Kelch like family member 11", "type": "synonym", "evidence": [ { "id": "A0A8V0ZS98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS98/entry#names_and_taxonomy" } ] }, { "name": "kelch-like protein 11", "type": "synonym", "evidence": [ { "id": "XP_003642870", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642870" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052558.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_003642870.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003642870", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642870" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZS98", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS98" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "KLHL11", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS98", "locus": { "chromosome": "27", "start_pos": 4696702, "end_pos": 4699243, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022866", "url": "https://www.ensembl.org/id/ENSGALG00010022866" } ] } } ], "crossref": [ { "id": "A0A8V0ZS98", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZS98", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd18241", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18241", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18451", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18451", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "428313", "url": "https://www.ncbi.nlm.nih.gov/gene/428313", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006652", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006652", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011043", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011043", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011705", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011705", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015915", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015915", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:428313", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428313", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LWSSHMA", "url": "https://omabrowser.org/oma/group/LWSSHMA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZS98", "url": "https://www.orthodb.org/?gene=A0A8V0ZS98", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24412", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24412", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24412:SF420", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24412:SF420", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00651", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00651", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07707", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07707", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13964", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13964", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-8951664", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8951664", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-983168", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983168", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003642870", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642870", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZS98", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS98", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZS98-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS98-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSDKMAAAAASPQPQPGPGPPAAEEEGGGPRGGGADGEAEAEEFGCPAHCSDLAWRQNEQRRHGLYCDITLAFGGGRPGAAREYRAHRSVLAAATEYFTPLLSGGFAESRSGRVELQKWSSEGGPDPDTVEAVIGFMYTGAIRVSPGNVHEVLEMADRFLLTRLKEFCGEFLKKKLNLSNCVAVHSLAHMYSLSQLALRAQDMIRRNFHRVIQDEEFYTLPFHLIRDWLSDSEITVDSEEILFETVLKWVQRNPEERERYFEELFKLLRLSQMKPTYLTRHVKSERLVSSNEACVRLVSDAVESHALRSENLQSGNLQHSTCPAALLPRFGQNMDVIMVIGGVSEGGDYLSECVGYFIDEDRWVNLPHIHNHLDGHAVAVTESYVYVAGSMEPGFAKTVERYNPNRNIWEQVSNLITRKHSFGLTEVKGNLYIIGGHGNFSPGFKDVAVYNPEQDKWHSLESAPKILRDVKAVSVEDRFVYVAARTPVDSDSEDGLRAVIIRYDTETRQWQDVESLPLIDNYCSFQMSVANTNFYHTASCCPKSYPIDNEEAKVKISGRASDEILESLPPEVLSIEGAAICYYKDDVFIIGGWKNSDDIDKQYRKEAYRYCAERKRWMLLPPMPQPRCRATACHVRIPFRCLQGTQRYPMPQNLMWQKDRIRQMQERQMQEIHRHSLSLRRMPRSQIEC", "length": 689, "header": "tr|A0A8V0ZS98-1|A0A8V0ZS98_CHICK Isoform 1 of Kelch like family member 11 OS=Gallus gallus OX=9031 GN=KLHL11 PE=4 SV=1 CANONICAL=A0A8V0ZS98-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZS98-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS98/entry#A0A8V0ZS98-1", "sequence": { "sequence": "MSDKMAAAAASPQPQPGPGPPAAEEEGGGPRGGGADGEAEAEEFGCPAHCSDLAWRQNEQRRHGLYCDITLAFGGGRPGAAREYRAHRSVLAAATEYFTPLLSGGFAESRSGRVELQKWSSEGGPDPDTVEAVIGFMYTGAIRVSPGNVHEVLEMADRFLLTRLKEFCGEFLKKKLNLSNCVAVHSLAHMYSLSQLALRAQDMIRRNFHRVIQDEEFYTLPFHLIRDWLSDSEITVDSEEILFETVLKWVQRNPEERERYFEELFKLLRLSQMKPTYLTRHVKSERLVSSNEACVRLVSDAVESHALRSENLQSGNLQHSTCPAALLPRFGQNMDVIMVIGGVSEGGDYLSECVGYFIDEDRWVNLPHIHNHLDGHAVAVTESYVYVAGSMEPGFAKTVERYNPNRNIWEQVSNLITRKHSFGLTEVKGNLYIIGGHGNFSPGFKDVAVYNPEQDKWHSLESAPKILRDVKAVSVEDRFVYVAARTPVDSDSEDGLRAVIIRYDTETRQWQDVESLPLIDNYCSFQMSVANTNFYHTASCCPKSYPIDNEEAKVKISGRASDEILESLPPEVLSIEGAAICYYKDDVFIIGGWKNSDDIDKQYRKEAYRYCAERKRWMLLPPMPQPRCRATACHVRIPFRCLQGTQRYPMPQNLMWQKDRIRQMQERQMQEIHRHSLSLRRMPRSQIEC", "length": 689, "header": "tr|A0A8V0ZS98-1|A0A8V0ZS98_CHICK Isoform 1 of Kelch like family member 11 OS=Gallus gallus OX=9031 GN=KLHL11 PE=4 SV=1 CANONICAL=A0A8V0ZS98-1" }, "locus": { "chromosome": "27", "start_pos": 4699235, "end_pos": 4697094, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055628.1", "url": "https://www.ensembl.org/id/ENSGALT00010055628.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033698.1", "url": "https://www.ensembl.org/id/ENSGALP00010033698.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:428313", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428313", "resource": "KEGG Pathway" }, { "id": "R-GGA-8951664", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8951664", "resource": "Reactome", "description": "Neddylation" }, { "id": "R-GGA-983168", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983168", "resource": "Reactome", "description": "Antigen processing: Ubiquitination & Proteasome degradation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1M7U1-1", "protein_name": "Kelch-like protein 11", "gene_name": "KLHL11", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAAAAVAAAAAAAAAASLQVLEMESMETAAAGSAGLAAEVRGSGTVDFGPGPGLSAMEASGGDPGPEAEDFECSSHCSELSWRQNEQRRQGLFCDITLCFGGAGGREFRAHRSVLAAATEYFTPLLSGQFSESRSGRVEMRKWSSEPGPEPDTVEAVIEYMYTGRIRVSTGSVHEVLELADRFLLIRLKEFCGEFLKKKLHLSNCVAIHSLAHMYTLSQLALKAADMIRRNFHKVIQDEEFYTLPFHLIRDWLSDLEITVDSEEVLFETVLKWVQRNAEERERYFEELFKLLRLSQMKPTYLTRHVKPERLVANNEVCVKLVADAVERHALRAENIQSGTFQHPASHVSLLPRYGQNMDVIMVIGGVSEGGDYLSECVGYFVDEDRWVNLPHIHNHLDGHAVAVTESYVYVAGSMEPGFAKTVERYNPNLNTWEHVCSLMTRKHSFGLTEVKGKLYSIGGHGNFSPGFKDVTVYNPELDKWHNLESAPKILRDVKALAIEDRFVYIAARTPVDRDTEDGLKAVITCYDTETRQWQDVESLPLIDNYCFFQMSVVNSNFYQTASCCPKSYSLENEEAIRKIANQVSDEILESLPPEVLSIEGAAICYYKDDVFIIGGWKNSDDIDKQYRKEAYRYCAERKRWMLLPPMPQPRCRATACHVRIPYRYLHGTQRYPMPQNLMWQKDRIRQMQEIHRHALNMRRVPSSQIEC", "length": 708 }, "evidence": [ { "id": "A0A8V0ZS98", "url": "https://omabrowser.org/oma/group/A0A8V0ZS98/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "D3ZPJ1-1", "protein_name": "Kelch-like protein 11", "gene_name": "Klhl11", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAAVAAAAAAAAAAASFQVLEMESMETAVAGSASLAAEVRGSGTVDFVTGAGISTLVDTGGGDPGPEAEDFECSTHCSELSWRQNEQRRQGLFCDITLCFGGAGGREFRAHRSVLAAATEYFTPLLSGQFSESRSGRVEMRKWSSEPGPEPDTVEAVIEYMYTGRIRVSTGSVHEVLELADRFLLIRLKEFCGEFLKKKLHLSNCVAIHSLAHMYTLSQLALKAADMIRRNFYKVIQDEEFYTLPFHLIRDWLSDLEITVDSEEVLFETVLKWVQRNAEERERYFEELFKLLRLSQMKPTYLTRHVKPERLVANNEVCVKLVAEAVERHALRAENIQSGTLQHPTSQVSLLPRYGQNMDVIMVIGGVSEGGDYLSECVGYFVDEDRWVNLPHIHNHLDGHAVAITESYVYVAGSMEPGFAKTVERYNPNLNTWEHVCSLMTRKHSFGLTEVKGKLYSIGGHGNFSPGFKDVTVYNPELDKWHNLESAPKILRDVKALAVEDRFVYIAARTPVDRDTEDGLKAVITCYDTETRQWQDVESLPLIDNYCFFQMSVVNSNFYQTASCCPKSYSLENEEAVRKIAGQVSDEILESLPPEVLSIEGAAICYYRDDVFIIGGWKNSDDIDKQYRKEAYRYCAERKRWMLLPPMPQPRCRATACHVRIPYRYLHGTQRYPMPQNLMWQKDRIRQMQEIHRHALNMRRVPSSQIEC", "length": 709 }, "evidence": [ { "id": "A0A8V0ZS98", "url": "https://omabrowser.org/oma/group/A0A8V0ZS98/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8CE33-1", "protein_name": "Kelch-like protein 11", "gene_name": "Klhl11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAAVAAAAAAAAAAASFQVLEMESMETAVAGSASLAAEVRGSGTVDFVTGAGISTLVDTGGSDPGPEAEDFECSTHCSELSWRQNEQRRQGLFCDITLCFGGAGGREFRAHRSVLAAATEYFTPLLSGQFSESRSGRVEMRKWSSEPGPEPDTVEAVIEYMYTGRIRVSTGSVHEVLELADRFLLIRLKEFCGEFLKKKLHLSNCVAIHSLAHMYTLSQLALKAADMIRRNFYKVIQDEEFYTLPFHLIRDWLSDLEITVDSEEVLFETVLKWVQRNAEERERYFEELFKLLRLSQMKPTYLTRHVKPERLVANNEVCVKLVAEAVERHALRAENIQSGTLQQPTSQVSLLPRYGQNMDVIMVIGGVSEGGDYLSECVGYFVDEDRWVNLPHIHNHLDGHAVAITESYVYVAGSMEPGFAKTVERYNPNLNTWEHVCSLMTRKHSFGLTEVKGKLYSIGGHGNFSPGFKDVTVYNPELDKWHNLESAPKILRDVKALAIEDRFVYIAARTPVDRDTEDGLKAVITCYDTETRQWQDVESLPLIDNYCFFQMSVVNSNFYQTASCCPKSYSLENEEAVRKIAGQVSDEILESLPPEVLSIEGAAICYYRDDVFIIGGWKNSDDIDKQYRKEAYRYCAERKRWMLLPPMPQPRCRATACHVRIPYRYLHGTQRYPMPQNLMWQKDRIRQMQEIHRHALNMRRVPSSQIEC", "length": 709 }, "evidence": [ { "id": "A0A8V0ZS98", "url": "https://omabrowser.org/oma/group/A0A8V0ZS98/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NVR0-1", "protein_name": "Kelch-like protein 11", "gene_name": "KLHL11", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAAAVAAAAAAAAAASLQVLEMESMETAAAGSAGLAAEVRGSGTVDFGPGPGISAMEASGGDPGPEAEDFECSSHCSELSWRQNEQRRQGLFCDITLCFGGAGGREFRAHRSVLAAATEYFTPLLSGQFSESRSGRVEMRKWSSEPGPEPDTVEAVIEYMYTGRIRVSTGSVHEVLELADRFLLIRLKEFCGEFLKKKLHLSNCVAIHSLAHMYTLSQLALKAADMIRRNFHKVIQDEEFYTLPFHLIRDWLSDLEITVDSEEVLFETVLKWVQRNAEERERYFEELFKLLRLSQMKPTYLTRHVKPERLVANNEVCVKLVADAVERHALRAENIQSGTCQHPTSHVSLLPRYGQNMDVIMVIGGVSEGGDYLSECVGYFVDEDRWVNLPHIHNHLDGHAVAVTESYVYVAGSMEPGFAKTVERYNPNLNTWEHVCSLMTRKHSFGLTEVKGKLYSIGGHGNFSPGFKDVTVYNPELDKWHNLESAPKILRDVKALAIEDRFVYIAARTPVDRDTEDGLKAVITCYDTETRQWQDVESLPLIDNYCFFQMSVVNSNFYQTASCCPKSYCLENEEAVRKIASQVSDEILESLPPEVLSIEGAAICYYKDDVFIIGGWKNSDDIDKQYRKEAYRYCAERKRWMLLPPMPQPRCRATACHVRIPYRYLHGTQRYPMPQNLMWQKDRIRQMQEIHRHALNMRRVPSSQIEC", "length": 708 }, "evidence": [ { "id": "A0A8V0ZS98", "url": "https://omabrowser.org/oma/group/A0A8V0ZS98/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZS98", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS98" } ], "pmid": "" }, { "name": "Cul3-RING ubiquitin ligase complex", "id": "GO:0031463", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031463", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZS98", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS98" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZS98", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS98" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "ubiquitin-like ligase-substrate adaptor activity", "id": "GO:1990756", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990756", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZS98", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS98" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 177, "end_pos": 179, "annotation": "n_glycosylation_sequon" }, { "start_pos": 439, "end_pos": 441, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZS98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS98" }, { "id": "PS50097", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50097" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BTB", "eco_id": "ECO_0000259", "start_pos": 67, "end_pos": 146, "start_aa": "Cys", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 177, "end_pos": 179 }, { "start_pos": 439, "end_pos": 441 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZSA3-1", "uniprot_ac": "A0A8V0ZSA3", "uniprot_id": "A0A8V0ZSA3_CHICK", "mass": { "chemical_mass": 118778.0, "monoisotopic_mass": 118778.0 }, "refseq": { "ac": "XP_015134197", "name": "probable E3 ubiquitin-protein ligase HERC4 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015134197" }, "gene_names": [ { "name": "HERC4", "type": "recommended", "evidence": [ { "id": "A0A8V0ZSA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSA3" } ] }, { "name": "HERC4", "type": "synonym", "evidence": [ { "id": "XP_015134197", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015134197" } ] } ], "protein_names": [ { "name": "HECT-type E3 ubiquitin transferase", "type": "recommended", "evidence": [ { "id": "A0A8V0ZSA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSA3/entry#names_and_taxonomy" } ] }, { "name": "2.3.2.26", "type": "synonym", "evidence": [ { "id": "A0A8V0ZSA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSA3/entry#names_and_taxonomy" } ] }, { "name": "probable E3 ubiquitin-protein ligase HERC4 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015134197", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015134197" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052537.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015134197", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015134197" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSA3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSA3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "HERC4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSA3", "locus": { "chromosome": "6", "start_pos": 11192288, "end_pos": 11223614, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022858", "url": "https://www.ensembl.org/id/ENSGALG00010022858" } ] } } ], "crossref": [ { "id": "A0A8V0ZSA3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZSA3", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00078", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00078", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "423683", "url": "https://www.ncbi.nlm.nih.gov/gene/423683", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000408", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000408", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000569", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000569", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009091", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009091", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035983", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035983", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051709", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051709", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058923", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058923", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:423683", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423683", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FKSQACW", "url": "https://omabrowser.org/oma/group/FKSQACW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZK21", "url": "https://www.orthodb.org/?gene=A0A8V0ZK21", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZQF1", "url": "https://www.orthodb.org/?gene=A0A8V0ZQF1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZSA3", "url": "https://www.orthodb.org/?gene=A0A8V0ZSA3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZXT7", "url": "https://www.orthodb.org/?gene=A0A8V0ZXT7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45622", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45622", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45622:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45622:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45700", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45700", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45700:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45700:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00415", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00415", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00632", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00632", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25390", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25390", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-983168", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983168", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015134197", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015134197", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZK21", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK21", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZK21-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK21-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQF1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQF1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQF1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQF1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZSA3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSA3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZSA3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSA3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZXT7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXT7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZXT7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXT7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLCWGNASFGQLGLGGIDEEIVLEPRKSDFFLNKRIRDVGCGLRHTVFVLDDGTVYTCGCNDLGQLGHEKARKRPEHVGALDAQNIVAVSCGEAHTLALNDKGQVYAWGLATDGQLGLPGTEECIRVPRNIKSLSEIQIVQVACGYYHSLALSKGSEVFSWGQNKYGQLGLGYEYKKQNSPHVIKSLLGIPFAQIAAGGAHSFVLTLSGAIFGWGRNKFGQLGLNDDNDRYVPTLLKSLRTQKVVHICCGEDHTAALTKEGGVFTFGAGGYGQLGHNSTSHEINPRKVFELMGSLVTQITCGRQHTTAFVPSSGRIYSFGLGGNGQLGTGTTSNRKSPFTVKGNWLPYSTQCLIPADSEQYYCVKRIFSGGDQSFAHYFYPQNMVPPDDFRYPDLLKQIWTVNETFIQRLLTFPSGRLPVEIANEIDGTFSSAGCLNGSFLALSNDDHYKTSVRFSGVDMNAARLLFHKLIQPDHAHISQQVAASLEKNLIPKLSSSLPDVEALRLYLTLPECPLMSDANNFTTLAIPFGTAILKLEKAPLKVLENWWSVLEPPLFLKIVELYKDVVVHLLKLYKIGIPPSERRIFTNFLHTAFRVLEILHRVNERGQVIQYDRFYIHEIQDLIDIRNDYVNWVQQQVFGMDVNHGLTELTDMPVTICTYPFVFDAQAKTTLLQTDAVMQMQMAVDQAHRQNLSSLFLPVFESVNPCLILMVRRDNIVGDAVEVLRKTKNVDYKKPLKVIFVGEEAVDVGGVRKEFFLLIMRELLDPKYGMFRYYEESRLIWFSDKTFEDSDLFHLIGVVCGLAIYNFTIVDLHFPLALYKKLLNKKPSLDDLKELMPDVGRGMQQLLDYPEDDIEEAFCLNFTITVENFGTTEIKELVPNGADIPVVKHNRQDFVDAYVDYIFNKSVASLFSAFHAGFHKVCGGKVLQLFQPSELQSMVIGNTNYDWKELEKNTEYKGEYWADHPTIKIFWEVFHQLPLEKKKQFLLFLTGSDRIPILGMKCLKLVIQPTGGGEGYLPVAHTCFNLLDLPKYTDKETLKSKLIQAIDHYEGFSLV", "length": 1056, "header": "tr|A0A8V0ZSA3-1|A0A8V0ZSA3_CHICK Isoform 1 of HECT-type E3 ubiquitin transferase OS=Gallus gallus OX=9031 GN=HERC4 PE=1 SV=1 CANONICAL=A0A8V0ZSA3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZK21-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSA3/entry#A0A8V0ZK21-1", "sequence": { "sequence": "MLCWGNASFGQLGLGGIDEEIVLEPRKSDFFLNKRIRDVGCGLRHTVFVLDDGTVYTCGCNDLGQLGHEKARKRPEHVGALDAQNIVAVSCGEAHTLALNDKGQVYAWGLATDGQLGLPGTEECIRVPRNIKSLSEIQIVQVACGYYHSLALSKGSEVFSWGQNKYGQLGLGYEYKKQNSPHVIKSLLGIPFAQIAAGGAHSFVLTLSGAIFGWGRNKFGQLGLNDDNDRYVPTLLKSLRTQKVVHICCGEDHTAALTKEGGVFTFGAGGYGQLGHNSTSHEINPRKVFELMGSLVTQITCGRQHTTAFVPSSGRIYSFGLGGNGQLGTGTTSNRKSPFTVKGNWLPYSTQCLIPADSEQYYCVKRIFSGGDQSFAHYFYPQNMVPPDDFRYPDLLKQIWTVNETFIQRLLTFPSGRLPVEIANEIDGTFSSAGCLNGSFLALSNDDHYKTSVRFSGVDMNAARLLFHKLIQPDHAHISQQVAASLEKNLIPKLSSSLPDVEALRLYLTLPECPLMSDANNFTTLAIPFGTAILKLEKAPLKVLENWWSVLEPPLFLKIVELYKDVVVHLLKLYKIGIPPSERRIFTNFLHTAFRVLEILHRVNERGQVIQYDRFYIHEIQDLIDIRNDYVNWVQQQVFGMNLSSLFLPVFESVNPCLILMVRRDNIVGDAVEVLRKTKNVDYKKPLKVIFVGEEAVDVGGVRKEFFLLIMRELLDPKYGMFRYYEESRLIWFSDKTFEDSDLFHLIGVVCGLAIYNFTIVDLHFPLALYKKLLNKKPSLDDLKELMPDVGRGMQQLLDYPEDDIEEAFCLNFTITVENFGTTEIKELVPNGADIPVVKHNRQDFVDAYVDYIFNKSVASLFSAFHAGFHKVCGGKVLQLFQPSELQSMVIGNTNYDWKELEKNTEYKGEYWADHPTIKIFWEVFHQLPLEKKKQFLLFLTGSDRIPILGMKCLKLVIQPTGGGEGYLPVAHTCFNLLDLPKYTDKETLKSKLIQAIDHYEGFSLV", "length": 1006, "header": "tr|A0A8V0ZK21-1|A0A8V0ZK21_CHICK Computationally mapped isoform of HECT-type E3 ubiquitin transferase OS=Gallus gallus OX=9031 GN=HERC4 PE=1 SV=1 CANONICAL=A0A8V0ZSA3-1" }, "locus": { "chromosome": "6", "start_pos": 11221312, "end_pos": 11193525, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055639.1", "url": "https://www.ensembl.org/id/ENSGALT00010055639.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033704.1", "url": "https://www.ensembl.org/id/ENSGALP00010033704.1" } ] } }, { "isoform_ac": "A0A8V0ZQF1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSA3/entry#A0A8V0ZQF1-1", "sequence": { "sequence": "MLCWGNASFGQLGLGGIDEEIVLEPRKSDFFLNKRIRDVGCGLRHTVFVLDDGTVYTCGCNDLGQLGHEKARKRPEHVGALDAQNIVAVSCGEAHTLALNDKGQVYAWGLATDGQLGLPGTEECIRVPRNIKSLSEIQIVQVACGYYHSLALSKGSEVFSWGQNKYGQLGLGYEYKKQNSPHVIKSLLGIPFAQIAAGGAHSFVLTLSGAIFGWGRNKFGQLGLNDDNDRYVPTLLKSLRTQKVVHICCGEDHTAALTKEGGVFTFGAGGYGQLGHNSTSHEINPRKVFELMGSLVTQITCGRQHTTAFVPSSGRIYSFGLGGNGQLGTGTTSNRKSPFTVKGNWLPYSTQCLIPADSEQYYCVKRIFSGGDQSFAHYFYPQNMVPPDDFRYPDLLKQIWTVNETFIQRLLTFPSGRLPVEIANEIDGTFSSAGCLNGSFLALSNDDHYKTSVRFSGVDMNAARLLFHKLIQPDHAHISQQVAASLEKNLIPKLSSSLPDVEALRLYLTLPECPLMSDANNFTTLAIPFGTAILKLEKAPLKVLENWWSVLEPPLFLKIVELYKDVVVHLLKLYKIGIPPSERRIFTNFLHTAFRVLEILHRVNERGQVIQYDRFYIHEIQDLIDIRNDYVNWVQQQVFGMLTDMPVTICTYPFVFDAQAKTTLLQTDAVMQMQMAVDQAHRQNLSSLFLPVFESVNPCLILMVRRDNIVGDAVEVLRKTKNVDYKKPLKVIFVGEEAVDVGGVRKEFFLLIMRELLDPKYGMFRYYEESRLIWFSDKTFEDSDLFHLIGVVCGLAIYNFTIVDLHFPLALYKKLLNKKPSLDDLKELMPDVGRGMQQLLDYPEDDIEEAFCLNFTITVENFGTTEIKELVPNGADIPVVKHNRQDFVDAYVDYIFNKSVASLFSAFHAGFHKVCGGKVLQLFQPSELQSMVIGNTNYDWKELEKNTEYKGEYWADHPTIKIFWEVFHQLPLEKKKQFLLFLTGSDRIPILGMKCLKLVIQPTGGGEGYLPVAHTCFNLLDLPKYTDKETLKSKLIQAIDHYEGFSLV", "length": 1048, "header": "tr|A0A8V0ZQF1-1|A0A8V0ZQF1_CHICK Computationally mapped isoform of HECT-type E3 ubiquitin transferase OS=Gallus gallus OX=9031 GN=HERC4 PE=1 SV=1 CANONICAL=A0A8V0ZSA3-1" }, "locus": { "chromosome": "6", "start_pos": 11221312, "end_pos": 11193525, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055641.1", "url": "https://www.ensembl.org/id/ENSGALT00010055641.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033706.1", "url": "https://www.ensembl.org/id/ENSGALP00010033706.1" } ] } }, { "isoform_ac": "A0A8V0ZSA3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSA3/entry#A0A8V0ZSA3-1", "sequence": { "sequence": "MLCWGNASFGQLGLGGIDEEIVLEPRKSDFFLNKRIRDVGCGLRHTVFVLDDGTVYTCGCNDLGQLGHEKARKRPEHVGALDAQNIVAVSCGEAHTLALNDKGQVYAWGLATDGQLGLPGTEECIRVPRNIKSLSEIQIVQVACGYYHSLALSKGSEVFSWGQNKYGQLGLGYEYKKQNSPHVIKSLLGIPFAQIAAGGAHSFVLTLSGAIFGWGRNKFGQLGLNDDNDRYVPTLLKSLRTQKVVHICCGEDHTAALTKEGGVFTFGAGGYGQLGHNSTSHEINPRKVFELMGSLVTQITCGRQHTTAFVPSSGRIYSFGLGGNGQLGTGTTSNRKSPFTVKGNWLPYSTQCLIPADSEQYYCVKRIFSGGDQSFAHYFYPQNMVPPDDFRYPDLLKQIWTVNETFIQRLLTFPSGRLPVEIANEIDGTFSSAGCLNGSFLALSNDDHYKTSVRFSGVDMNAARLLFHKLIQPDHAHISQQVAASLEKNLIPKLSSSLPDVEALRLYLTLPECPLMSDANNFTTLAIPFGTAILKLEKAPLKVLENWWSVLEPPLFLKIVELYKDVVVHLLKLYKIGIPPSERRIFTNFLHTAFRVLEILHRVNERGQVIQYDRFYIHEIQDLIDIRNDYVNWVQQQVFGMDVNHGLTELTDMPVTICTYPFVFDAQAKTTLLQTDAVMQMQMAVDQAHRQNLSSLFLPVFESVNPCLILMVRRDNIVGDAVEVLRKTKNVDYKKPLKVIFVGEEAVDVGGVRKEFFLLIMRELLDPKYGMFRYYEESRLIWFSDKTFEDSDLFHLIGVVCGLAIYNFTIVDLHFPLALYKKLLNKKPSLDDLKELMPDVGRGMQQLLDYPEDDIEEAFCLNFTITVENFGTTEIKELVPNGADIPVVKHNRQDFVDAYVDYIFNKSVASLFSAFHAGFHKVCGGKVLQLFQPSELQSMVIGNTNYDWKELEKNTEYKGEYWADHPTIKIFWEVFHQLPLEKKKQFLLFLTGSDRIPILGMKCLKLVIQPTGGGEGYLPVAHTCFNLLDLPKYTDKETLKSKLIQAIDHYEGFSLV", "length": 1056, "header": "tr|A0A8V0ZSA3-1|A0A8V0ZSA3_CHICK Isoform 1 of HECT-type E3 ubiquitin transferase OS=Gallus gallus OX=9031 GN=HERC4 PE=1 SV=1 CANONICAL=A0A8V0ZSA3-1" }, "locus": { "chromosome": "6", "start_pos": 11221312, "end_pos": 11193525, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055637.1", "url": "https://www.ensembl.org/id/ENSGALT00010055637.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033703.1", "url": "https://www.ensembl.org/id/ENSGALP00010033703.1" } ] } }, { "isoform_ac": "A0A8V0ZXT7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSA3/entry#A0A8V0ZXT7-1", "sequence": { "sequence": "ERRSKDQTACGHTTAFVPSSGRIYSFGLGGNGQLGTGTTSNRKSPFTVKGNWLPYSTQCLIPADSEQYYCVKRIFSGGDQSFAHYFYPQNMVPPDDFRYPDLLKQIWTVNETFIQRLLTFPSGRLPVEIANEIDGTFSSAGCLNGSFLALSNDDHYKTSVRFSGVDMNAARLLFHKLIQPDHAHISQQVAASLEKNLIPKLSSSLPDVEALRLYLTLPECPLMSDANNFTTLAIPFGTAILKLEKAPLKVLENWWSVLEPPLFLKIVELYKDVVVHLLKLYKIGIPPSERRIFTNFLHTAFRVLEILHRVNERGQVIQYDRFYIHEIQDLIDIRNDYVNWVQQQVFGMLTDMPVTICTYPFVFDAQAKTTLLQTDAVMQMQMAVDQAHRQNLSSLFLPVFESVNPCLILMVRRDNIVGDAVEVLRKTKNVDYKKPLKVIFVGEEAVDVGGVRKEFFLLIMRELLDPKYGMFRYYEESRLIWFSDKTFEDSDLFHLIGVVCGLAIYNFTIVDLHFPLALYKKLLNKKPSLDDLKELMPDVGRGMQQLLDYPEDDIEEAFCLNFTITVENFGTTEIKELVPNGADIPVVKHNRQDFVDAYVDYIFNKSVASLFSAFHAGFHKVCGGKVLQLFQPSELQSMVIGNTNYDWKELEKNTEYKGEYWADHPTIKIFWEVFHQLPLEKKKQFLLFLTGSDRIPILGMKCLKLVIQPTGGGEGYLPVAHTCFNLLDLPKYTDKETLKSKLIQAIDHYEGFSLV", "length": 755, "header": "tr|A0A8V0ZXT7-1|A0A8V0ZSA3_CHICK Computationally mapped isoform of HECT-type E3 ubiquitin transferase OS=Gallus gallus OX=9031 GN=HERC4 PE=1 SV=1 CANONICAL=A0A8V0ZSA3-1" }, "locus": { "chromosome": "6", "start_pos": 11210836, "end_pos": 11193525, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055632.1", "url": "https://www.ensembl.org/id/ENSGALT00010055632.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033700.1", "url": "https://www.ensembl.org/id/ENSGALP00010033700.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:423683", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423683", "resource": "KEGG Pathway" }, { "id": "R-GGA-983168", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983168", "resource": "Reactome", "description": "Antigen processing: Ubiquitination & Proteasome degradation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2LZF6-1", "protein_name": "Probable E3 ubiquitin-protein ligase HERC4", "gene_name": "Herc4", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MLCWGNASYGQLGLGGIDEEIVLEPRKSDFFANKKVRDVGCGLRHTVFVLDDGTVYTCGCNDLGQLGHEKSRKKPEQVVALDAQNIVAVSCGEAHTLALNDKGQVYSWGLDSDGQLGLLGSEEYIRVPRNIKSLSDIQIVQVACGYYHSLALSKASEVFCWGQNKYGQLGLGIDCKKQTSPQLIKSLLGIPFMQVAAGGAHSFVLTLSGAIFGWGRNKFGQLGLNDENDRYVPNLLKSLRSQKIVYICCGEDHTAALTKEGGVFTFGAGGYGQLGHNSTSHEINPRKVFELMGSIVTQVACGRQHTSAFVPSSGRIYSFGLGGNGQLGTGSTSNRKSPFTVKGNWFSYNGQCPQDIDSEDCFCVKRIFSGGDQSFSHYSNPQSCGPADDFRCPDPSKQIWTVNEALIQKWLSYPSGRFPVEIANEIDGTFSSSGCLNGSFLATSNDDHYRTGTKFSGVDMNAARLLFHKLIQPDHPQISQQVAASLEKNLIPKLTSSLPDVEALRFYLTLPECPLMSDSNNFTTIAIPFGTALVNLEKAPLKVLENWWSVLEPPLFLKIVELFKEVVVHLLKLYKIGIPPSERRIFNSFLHTALKVLEILHRVNEKTGQLIQYDKFYIHEVQDLIDIRNDYINWVQQQAYGVDVSHGLTELADIPVTICTYPFVFDAQAKTTLLQTDAVLQMQMAIDQAHRQNVSSLFLPVIESVNPCLILVVRRENIVGDAMEVLRKTKSIDYKKPLKVIFVGEDAVDAGGVRKEFFLLIMRELLDPKYGMFQYYEDSRLIWFSDKTFEDSDLFHLIGVICGLAIYNFTIVDLHFPLALYKKLLKRKPSLDDLKELMPDVGRSMQQLLDYPEDDIEETFCLNFTITVENFGATEVKELVVNGADTAVNKQNRQEFVDAYVDYIFNKSVASLFDAFHAGFHKVCGGKVLLLFQPNELQAMVIGNTNYDWKELEKNTEYKGDYWAEHPTIKIFWEVFHELPLEKKKQFLLFLTGSDRIPILGMKSLKLVIQSTGGGENYLPVSHTCFNLLDLPKYTEKETLRCKLIQAIDHNEGFSLI", "length": 1057 }, "evidence": [ { "id": "A0A8V0ZSA3", "url": "https://omabrowser.org/oma/group/A0A8V0ZSA3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "E1BAV2-1", "protein_name": "Probable E3 ubiquitin-protein ligase HERC4", "gene_name": "HERC4", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MLCWGNASFGQLGLGGIDEEIVLEPRKSDFFINKKVRDVGCGLRHTVFVLDDGTVYTCGCNDLGQLGHEKSRKKPEQVVALDAQNIVAVSCGEAHTLALNDKGQVYAWGLDSDGQLGLLGSEECIRVPRNIKSLSDIQIVQVACGYYHSLALSKASEVFCWGQNKYGQLGLGIDCKKQASPQLIKSLLGIPFMQIAAGGAHSFVLTLSGAIFGWGRNKFGQLGLNDENDRYVPNLLKSLRTQKIVYICCGEDHTAALTKEGGVFTFGAGGYGQLGHNSTSHEINPRKVFELMGSIVTQIACGRQHTSAFVPSSGRIYSFGLGGNGQLGTGSTSNRKSPFTVKGNWFPYNGQCPPDFDSEEYFCVKRIFSGGDQSFSHYSNPQNCGPPDDFRYPDPSKQIWTVNEALIQKWLSYPSGRFPVEIANEIDGTFSSSGCLNGSFLAVSNDDHYRTGTRFSGVDMNAARLLFHKLIQPDHPQIAQQVAASLEKNLIPKLTSSLPDVEALRFYLTLPECPLMSDSNNFTTIAIPFGTALVNLEKAPLKVLENWWSVLEPPLFLKIVELFKEVVVHLLKLYKIGIPPSERRIFNSFLHTALKVLEILHRVNEKSGQIIQYDKFYIHEVQELIDIRNDYIIWVQQQAYGMDVNHGLTELADIPVTICTYPFVFDAQAKTTLLQTDAVLQMQMAIDQAHRQNVSSLFLPVIESVNPCLILVVRRENIVGDAMEVLRKTKNIDYKKPLKVIFVGEDAVDAGGVRKEFFLLIMRELLDPKYGMFRYYEDSRLIWFSDKTFEDSDLFHLIGVICGLAIYNFTIVDLHFPLALYKKLLKKKPSLEDLKELVPDVGRSMQQLLDYPEDDVEETFCLNFTITVENFGATEVKELVLNGADTAVNKQNRQEFVDAYVDYIFNKSVASLFDAFHAGFHKVCGGKVLQLFQPNELQAMVIGNTNYDWKELEKNTEYKGEYWAEHPTIKMFWEVFHELPLEKKKQFLLFLTGSDRIPILGMKSLILVIQSTGGGEEYLPVSHTCFNLLDLPKYTDKETLRSKLIQAIDHNEGFSLI", "length": 1057 }, "evidence": [ { "id": "A0A8V0ZSA3", "url": "https://omabrowser.org/oma/group/A0A8V0ZSA3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q5GLZ8-1", "protein_name": "Probable E3 ubiquitin-protein ligase HERC4", "gene_name": "HERC4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLCWGNASFGQLGLGGIDEEIVLEPRKSDFFINKRVRDVGCGLRHTVFVLDDGTVYTCGCNDLGQLGHEKSRKKPEQVVALDAQNIVAVSCGEAHTLALNDKGQVYAWGLDSDGQLGLVGSEECIRVPRNIKSLSDIQIVQVACGYYHSLALSKASEVFCWGQNKYGQLGLGTDCKKQTSPQLLKSLLGIPFMQVAAGGAHSFVLTLSGAIFGWGRNKFGQLGLNDENDRYVPNLLKSLRSQKIVYICCGEDHTAALTKEGGVFTFGAGGYGQLGHNSTSHEINPRKVFELMGSIVTEIACGRQHTSAFVPSSGRIYSFGLGGNGQLGTGSTSNRKSPFTVKGNWYPYNGQCLPDIDSEEYFCVKRIFSGGDQSFSHYSSPQNCGPPDDFRCPNPTKQIWTVNEALIQKWLSYPSGRFPVEIANEIDGTFSSSGCLNGSFLAVSNDDHYRTGTRFSGVDMNAARLLFHKLIQPDHPQISQQVAASLEKNLIPKLTSSLPDVEALRFYLTLPECPLMSDSNNFTTIAIPFGTALVNLEKAPLKVLENWWSVLEPPLFLKIVELFKEVVVHLLKLYKIGIPPSERRIFNSFLHTALKVLEILHRVNEKMGQIIQYDKFYIHEVQELIDIRNDYINWVQQQAYGMDVNHGLTELADIPVTICTYPFVFDAQAKTTLLQTDAVLQMQMAIDQAHRQNVSSLFLPVIESVNPCLILVVRRENIVGDAMEVLRKTKNIDYKKPLKVIFVGEDAVDAGGVRKEFFLLIMRELLDPKYGMFRYYEDSRLIWFSDKTFEDSDLFHLIGVICGLAIYNCTIVDLHFPLALYKKLLKKKPSLDDLKELMPDVGRSMQQLLDYPEDDIEETFCLNFTITVENFGATEVKELVLNGADTAVNKQNRQEFVDAYVDYIFNKSVASLFDAFHAGFHKVCGGKVLLLFQPNELQAMVIGNTNYDWKELEKNTEYKGEYWAEHPTIKIFWEVFHELPLEKKKQFLLFLTGSDRIPILGMKSLKLVIQSTGGGEEYLPVSHTCFNLLDLPKYTEKETLRSKLIQAIDHNEGFSLI", "length": 1057 }, "evidence": [ { "id": "A0A8V0ZSA3", "url": "https://omabrowser.org/oma/group/A0A8V0ZSA3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5PQN1-1", "protein_name": "Probable E3 ubiquitin-protein ligase HERC4", "gene_name": "Herc4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLCWGNASYGQLGLGGIDEEIVLEPRKSDFFVNKKVRDVGCGLRHTVFVLDDGTVYTCGCNDLGQLGHEKSRKKPEQVVALDAQNIVAVSCGEAHTLALNDKGQVYAWGLDSDGQLGLQGSEECIRVPRNIKSLSDIQIVQVACGYYHSLALSKASEVFCWGQNKYGQLGLGIECQKQTSPQLIKSLLGIPFMQVAAGGAHSFVLTLSGAIFGWGRNKFGQLGLNDENDRYVPNLLKSLRSQKIVYICCGEDHTAALTKEGGVFTFGAGGYGQLGHNSTSHEINPRKVFELMGSIVTQIACGRQHTSAFVPSSGRIYSFGLGGNGQLGTGSTSNRKSPFTVKGNWFSYNGQCPQDIGSEDYFCVKRIFSGGDQSFSHYSSPQSCGPPDDFRRSDPSKQIWTVNEALIQKWLSYPSGRFPVEIANEIDGTFSSSGCLNGSFLAVSNDDHYRTGTRFSGVDMNAARLLFHRLIQPDHPQISQQVAASLEKNLIPKLTSSLPDVEALRFYLTLPECPLMSDCNNFTTIAIPFGTALVNLEKAPLKVLENWWSVLEPPLFLKIVELFKEVVVHLLKLYKIGIPPSERRIFNSFLHTALKVLEILHRVNERTGQLIQYDKFYIHEVQELIDIRNDYINWVQQQAYGVDVSHGITELADIPVTICTYPFVFDAQAKTTLLQTDAVLQMQMAIDQAHRQNVSSLFLPVIESVNPCLILVVRRENIVGDAMEVLRKTKNIDYKKPLKVIFVGEDAVDAGGVRKEFFLLIMRELLDPKYGMFRYYEDSRLIWFSDKTFEDSDLFHLIGVICGLAIYNFTIVDLHFPLALYKKLLKRKPSLDDLKELMPDVGRSMQQLLDYPEDDIEETFCLNFTITVENFGATEVKELVLNGADTAVNKQNRQEFVDAYVDYIFNKSVASLFDAFHAGFHKVCGGKVLLLFQPNELQAMVIGNTNYDWKELEKNTEYKGEYWAEHPTIKIFWEVFHELPLEKKKQFLLFLTGSDRIPILGMKSLKLVIQSTGGGESYLPVSHTCFNLLDLPKYTEKETLRCKLIQAIDHNEGFSLI", "length": 1057 }, "evidence": [ { "id": "A0A8V0ZSA3", "url": "https://omabrowser.org/oma/group/A0A8V0ZSA3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6PAV2-1", "protein_name": "Probable E3 ubiquitin-protein ligase HERC4", "gene_name": "Herc4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLCWGNASYGQLGLGGIDEEIVLEPRRSDFFVNKKVRDVGCGLRHTVFVLDDGTVYTCGCNDLGQLGHEKSRKKPEQVVALDAQNIVAVACGEAHTLALNDKGQVYAWGLDSDGQLGLQGSEECIRVPRNIKSLSDIQIVQVACGYYHSLALSKASEVFCWGQNKYGQLGLGIDCQKQTSPQLIKSLLGIPFMQVAAGGAHSFVLTLSGAIFGWGRNKFGQLGLNDENDRYVPNLLKSLRSQKIVYICCGEDHTAALTKEGGVFTFGAGGYGQLGHNSTSHEINPRKVFELMGSIVTQVACGRQHTSAFVPSSGRIYSFGLGGNGQLGTGSTSNRKSPFTVKGNWFSYNGQCPQDIGSEDYFCVKRIFSGGDQSFSHYSSPQNCGPPDDFRCSDPSKQIWTVNEALIQKWLSYPSGRFPVEIANEIDGTFSSSGCLNGSFLAISNDDHYRTGTRFSGVDMNAARLLFHKLIQPDHPQISQQVAASLEKNLIPKLTSSLPDVEALRFYLTLPECPLMSDCNNFTTIAIPFGTALVNLEKAPLKVLENWWSVLEPPLFLKIVELFKEVVVHLLKLYKIGIPPSERRIFNSFLHTALKVLEILHRVNEKTGQLIQYDKFYIHEVQELIDIRNDYINWVQQQAYGVDVSHGVTELADIPVTICTYPFVFDAQAKTTLLQTDAVLQMQMAIDQAHRQNVSSLFLPVIESVNPCLILVVRRENIVGDAMEVLRKTKNIDYKKPLKVIFVGEDAVDAGGVRKEFFLLIMRELLDPKYGMFRYYEDSRLIWFSDKTFEDSDLFHLIGVICGLAIYNFTIVDLHFPLALYKKLLKRKPSLDDLKELMPAVGRSMQQLLDYPEDDIEETFCLNFTITVENFGATEVKELVLNGADTAVNRQNRQEFVDAYVDYIFNKSVASLFDAFHAGFHKVCGGKVLLLFQPNELQAMVIGNTNYDWKELEKNTEYKGEYWADHPTIKIFWEVFHELPLEKKKQFLLFLTGSDRIPILGMKSLKLVIQSTGGGESYLPVSHTCFNLLDLPKYTEKETLRCKLIQAIDHNEGFSLI", "length": 1057 }, "evidence": [ { "id": "A0A8V0ZSA3", "url": "https://omabrowser.org/oma/group/A0A8V0ZSA3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSA3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSA3" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSA3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSA3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "spermatogenesis", "id": "GO:0007283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007283", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSA3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSA3" } ], "pmid": "" }, { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSA3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSA3" } ], "pmid": "" }, { "name": "ubiquitin-dependent protein catabolic process", "id": "GO:0006511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006511", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSA3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSA3" } ], "pmid": "" }, { "name": "negative regulation of smoothened signaling pathway", "id": "GO:0045879", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045879", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSA3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSA3" } ], "pmid": "" }, { "name": "protein polyubiquitination", "id": "GO:0000209", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000209", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSA3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSA3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSA3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSA3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 277, "end_pos": 279, "annotation": "n_glycosylation_sequon" }, { "start_pos": 403, "end_pos": 405, "annotation": "n_glycosylation_sequon" }, { "start_pos": 437, "end_pos": 439, "annotation": "n_glycosylation_sequon" }, { "start_pos": 521, "end_pos": 523, "annotation": "n_glycosylation_sequon" }, { "start_pos": 692, "end_pos": 694, "annotation": "n_glycosylation_sequon" }, { "start_pos": 6, "end_pos": 8, "annotation": "n_glycosylation_sequon" }, { "start_pos": 807, "end_pos": 809, "annotation": "n_glycosylation_sequon" }, { "start_pos": 862, "end_pos": 864, "annotation": "n_glycosylation_sequon" }, { "start_pos": 905, "end_pos": 907, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-GGA-983140", "name": "Transfer of Ub from E2 to substrate and release of E2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0X324-1", "A0A8V0XEM6-1", "A0A8V0XJC4-1", "A0A8V0XQR1-1", "A0A8V1AC19-1", "A0A8V1AC55-1", "A0A8V1AKB8-1", "A0A8V1ALH0-1", "F1NL19-1", "F1NRC6-1", "F1NTZ8-1", "A0A8V0YHL7-1", "A0A8V0YPW4-1", "A0A8V0YRM6-1", "A0A8V0YV22-1", "A0A8V0YVP3-1", "A0A8V0Z2L5-1", "F1NL77-1", "E1C982-1", "A0A3Q2UC96-1", "Q5ZKX6-1", "Z4YJC3-1", "A0A8V0XQU7-1", "A0A8V0Y5C9-1", "A0A8V1AL09-1", "A0A8V1AML5-1", "A0A8V1AP69-1", "F1NVY8-1", "R4GIV8-1", "A0A8V0ZJ49-1", "A0A8V0ZJV9-1", "A0A8V0ZL18-1", "A0A8V0ZM17-1", "A0A8V0ZSH4-1", "A0A8V0ZVX3-1", "A0A8V0ZW26-1", "A0A8V1A0Z6-1", "A0A8V0ZZH3-1", "A0A8V1A052-1", "A0A8V1A0X2-1", "A0A8V1A1I4-1", "A0A8V1A2W7-1", "A0A8V1A5P4-1", "A0A8V1A7T1-1", "A0A8V0XTY5-1", "A0A8V0Y5B5-1", "A0A8V0YL05-1", "A0A8V0Z082-1", "A0A8V0ZS27-1", "A0A8V1A9M0-1", "E1BZ35-1", "E1C3Q9-1", "F1NC08-1", "F1P2G0-1", "A0A8V0YY10-1", "A0A8V0YYC5-1", "A0A8V0Z1W7-1", "A0A8V0Z4C8-1", "A0A8V0Z596-1", "A0A1D5P284-1", "A0A8V0ZF21-1", "A0A3Q2U2G8-1", "A0A8V1A4H7-1", "A0A8V1A1N8-1", "A0A8V1A233-1", "A0A8V1A7P9-1", "A0A8V1ACU3-1", "A0A8V0ZSA3-1", "E1C656-1", "A0A8V0Y0Q7-1", "A0A8V0Y059-1", "A0A8V0Y5C7-1", "A0A8V0YCS7-1", "A0A8V0YDQ1-1", "A0A8V0YFD9-1", "A0A8V0YGF4-1", "A0A8V0YJK8-1", "A0A8V0YLY7-1", "A0A1D5NVE2-1", "A0A8V0ZKK3-1", "A0A8V0ZKQ3-1" ], "evidence": [ { "id": "R-GGA-983140", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983140" } ] }, { "id": "R-GGA-983147", "name": "Release of E3 from polyubiquitinated substrate", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XEM6-1", "A0A8V0XJC4-1", "A0A8V1AC55-1", "A0A8V1AKB8-1", "A0A8V1ALH0-1", "F1NRC6-1", "F1NTZ8-1", "A0A8V0YHL7-1", "A0A8V0YRM6-1", "A0A8V0YV22-1", "A0A8V0YVP3-1", "A0A8V0Z2L5-1", "F1NL77-1", "E1C982-1", "A0A3Q2UC96-1", "Z4YJC3-1", "A0A8V0XQU7-1", "A0A8V0Y5C9-1", "A0A8V1AL09-1", "A0A8V1AML5-1", "A0A8V1AP69-1", "F1NVY8-1", "A0A8V0ZJ49-1", "A0A8V0ZJV9-1", "A0A8V0ZL18-1", "A0A8V0ZM17-1", "A0A8V0ZSH4-1", "A0A8V0ZVX3-1", "A0A8V0ZW26-1", "A0A8V1A0Z6-1", "A0A8V0ZZH3-1", "A0A8V1A0X2-1", "A0A8V1A2W7-1", "A0A8V1A7T1-1", "A0A8V0XTY5-1", "A0A8V0Y5B5-1", "A0A8V0YL05-1", "A0A8V0ZS27-1", "A0A8V1A9M0-1", "E1BZ35-1", "E1C3Q9-1", "F1NC08-1", "F1P2G0-1", "A0A8V0YYC5-1", "A0A8V0Z4C8-1", "A0A8V0Z596-1", "A0A1D5P284-1", "A0A8V0ZF21-1", "A0A3Q2U2G8-1", "A0A8V1A1N8-1", "A0A8V1A233-1", "A0A8V1A7P9-1", "A0A8V0ZSA3-1", "E1C656-1", "A0A8V0Y0Q7-1", "A0A8V0Y5C7-1", "A0A8V0YCS7-1", "A0A8V0YDQ1-1", "A0A8V0YGF4-1", "A0A8V0YJK8-1", "A0A8V0YLY7-1", "A0A8V0ZKK3-1", "A0A8V0ZKQ3-1" ], "evidence": [ { "id": "R-GGA-983147", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983147" } ] }, { "id": "R-GGA-983156", "name": "Polyubiquitination of substrate", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0X324-1", "A0A8V0XEM6-1", "A0A8V0XJC4-1", "A0A8V0XQR1-1", "A0A8V1AC19-1", "A0A8V1AC55-1", "A0A8V1AKB8-1", "A0A8V1ALH0-1", "F1NL19-1", "F1NRC6-1", "F1NTZ8-1", "A0A8V0YHL7-1", "A0A8V0YPW4-1", "A0A8V0YRM6-1", "A0A8V0YV22-1", "A0A8V0YVP3-1", "A0A8V0Z2L5-1", "F1NL77-1", "E1C982-1", "A0A3Q2UC96-1", "Q5ZKX6-1", "Z4YJC3-1", "A0A8V0XQU7-1", "A0A8V0Y5C9-1", "A0A8V1AL09-1", "A0A8V1AML5-1", "A0A8V1AP69-1", "F1NVY8-1", "R4GIV8-1", "A0A8V0ZJ49-1", "A0A8V0ZJV9-1", "A0A8V0ZL18-1", "A0A8V0ZM17-1", "A0A8V0ZSH4-1", "A0A8V0ZVX3-1", "A0A8V0ZW26-1", "A0A8V1A0Z6-1", "A0A8V0ZZH3-1", "A0A8V1A052-1", "A0A8V1A0X2-1", "A0A8V1A1I4-1", "A0A8V1A2W7-1", "A0A8V1A5P4-1", "A0A8V1A7T1-1", "A0A8V0XTY5-1", "A0A8V0Y5B5-1", "A0A8V0YL05-1", "A0A8V0Z082-1", "A0A8V0ZS27-1", "A0A8V1A9M0-1", "E1BZ35-1", "E1C3Q9-1", "F1NC08-1", "F1P2G0-1", "A0A8V0YY10-1", "A0A8V0YYC5-1", "A0A8V0Z1W7-1", "A0A8V0Z4C8-1", "A0A8V0Z596-1", "A0A1D5P284-1", "A0A8V0ZF21-1", "A0A3Q2U2G8-1", "A0A8V1A4H7-1", "A0A8V1A1N8-1", "A0A8V1A233-1", "A0A8V1A7P9-1", "A0A8V1ACU3-1", "A0A8V0ZSA3-1", "E1C656-1", "A0A8V0Y0Q7-1", "A0A8V0Y059-1", "A0A8V0Y5C7-1", "A0A8V0YCS7-1", "A0A8V0YDQ1-1", "A0A8V0YFD9-1", "A0A8V0YGF4-1", "A0A8V0YJK8-1", "A0A8V0YLY7-1", "A0A1D5NVE2-1", "A0A8V0ZKK3-1", "A0A8V0ZKQ3-1" ], "evidence": [ { "id": "R-GGA-983156", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983156" } ] }, { "id": "R-GGA-983157", "name": "Interaction of E3 with substrate and E2-Ub complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0X324-1", "A0A8V0XEM6-1", "A0A8V0XJC4-1", "A0A8V0XQR1-1", "A0A8V1AC19-1", "A0A8V1AC55-1", "A0A8V1AKB8-1", "A0A8V1ALH0-1", "F1NL19-1", "F1NRC6-1", "F1NTZ8-1", "A0A8V0YHL7-1", "A0A8V0YPW4-1", "A0A8V0YRM6-1", "A0A8V0YV22-1", "A0A8V0YVP3-1", "A0A8V0Z2L5-1", "F1NL77-1", "E1C982-1", "A0A3Q2UC96-1", "Q5ZKX6-1", "Z4YJC3-1", "A0A8V0XQU7-1", "A0A8V0Y5C9-1", "A0A8V1AL09-1", "A0A8V1AML5-1", "A0A8V1AP69-1", "F1NVY8-1", "R4GIV8-1", "A0A8V0ZJ49-1", "A0A8V0ZJV9-1", "A0A8V0ZL18-1", "A0A8V0ZM17-1", "A0A8V0ZSH4-1", "A0A8V0ZVX3-1", "A0A8V0ZW26-1", "A0A8V1A0Z6-1", "A0A8V0ZZH3-1", "A0A8V1A052-1", "A0A8V1A0X2-1", "A0A8V1A1I4-1", "A0A8V1A2W7-1", "A0A8V1A5P4-1", "A0A8V1A7T1-1", "A0A8V0XTY5-1", "A0A8V0Y5B5-1", "A0A8V0YL05-1", "A0A8V0Z082-1", "A0A8V0ZS27-1", "A0A8V1A9M0-1", "E1BZ35-1", "E1C3Q9-1", "F1NC08-1", "F1P2G0-1", "A0A8V0YY10-1", "A0A8V0YYC5-1", "A0A8V0Z1W7-1", "A0A8V0Z4C8-1", "A0A8V0Z596-1", "A0A1D5P284-1", "A0A8V0ZF21-1", "A0A3Q2U2G8-1", "A0A8V1A4H7-1", "A0A8V1A1N8-1", "A0A8V1A233-1", "A0A8V1A7P9-1", "A0A8V1ACU3-1", "A0A8V0ZSA3-1", "E1C656-1", "A0A8V0Y0Q7-1", "A0A8V0Y059-1", "A0A8V0Y5C7-1", "A0A8V0YCS7-1", "A0A8V0YDQ1-1", "A0A8V0YFD9-1", "A0A8V0YGF4-1", "A0A8V0YJK8-1", "A0A8V0YLY7-1", "A0A1D5NVE2-1", "A0A8V0ZKK3-1", "A0A8V0ZKQ3-1" ], "evidence": [ { "id": "R-GGA-983157", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983157" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5NVE2", "gene_name": "UBE2Q1", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A1D5NVE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVE2" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A1D5NVE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVE2" } ] } ] }, { "uniprot_ac": "A0A1D5P284", "gene_name": "UBR2", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A1D5P284", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P284" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A1D5P284", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P284" } ] } ] }, { "uniprot_ac": "A0A3Q2U2G8", "gene_name": "TRIM9", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A3Q2U2G8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U2G8" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A3Q2U2G8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U2G8" } ] } ] }, { "uniprot_ac": "A0A3Q2UC96", "gene_name": "NEDD4L", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A3Q2UC96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UC96" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A3Q2UC96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UC96" } ] } ] }, { "uniprot_ac": "A0A8V0X324", "gene_name": "UBE2E1", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0X324", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X324" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0X324", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X324" } ] } ] }, { "uniprot_ac": "A0A8V0XEM6", "gene_name": "HERC2", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0XEM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEM6" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0XEM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEM6" } ] } ] }, { "uniprot_ac": "A0A8V0XJC4", "gene_name": "UBE3D", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0XJC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJC4" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0XJC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJC4" } ] } ] }, { "uniprot_ac": "A0A8V0XQR1", "gene_name": "UBE2H", "activity": [ { "ec_number": "2.3.2.24", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E1 ubiquitin-activating enzyme]-L-cysteine + N(6)-monoubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0XQR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQR1" } ] }, { "ec_number": "2.3.2.24", "activity": "", "evidence": [ { "id": "A0A8V0XQR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQR1" } ] } ] }, { "uniprot_ac": "A0A8V0XQU7", "gene_name": "RNF6", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0XQU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQU7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0XQU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQU7" } ] } ] }, { "uniprot_ac": "A0A8V0XTY5", "gene_name": "SH3RF1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0XTY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XTY5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0XTY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XTY5" } ] } ] }, { "uniprot_ac": "A0A8V0Y059", "gene_name": "UBE2D1", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0Y059", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y059" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0Y059", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y059" } ] } ] }, { "uniprot_ac": "A0A8V0Y0Q7", "gene_name": "RNF144B", "activity": [ { "ec_number": "2.3.2.31", "activity": "[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.", "evidence": [ { "id": "A0A8V0Y0Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y0Q7" } ] }, { "ec_number": "2.3.2.31", "activity": "", "evidence": [ { "id": "A0A8V0Y0Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y0Q7" } ] } ] }, { "uniprot_ac": "A0A8V0Y5B5", "gene_name": "LTN1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Y5B5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5B5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0Y5B5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5B5" } ] } ] }, { "uniprot_ac": "A0A8V0Y5C7", "gene_name": "CBLL1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Y5C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5C7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0Y5C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5C7" } ] } ] }, { "uniprot_ac": "A0A8V0Y5C9", "gene_name": "HERC3", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Y5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5C9" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0Y5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5C9" } ] } ] }, { "uniprot_ac": "A0A8V0YCS7", "gene_name": "RNF19A", "activity": [ { "ec_number": "2.3.2.31", "activity": "[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.", "evidence": [ { "id": "A0A8V0YCS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCS7" } ] }, { "ec_number": "2.3.2.31", "activity": "", "evidence": [ { "id": "A0A8V0YCS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCS7" } ] } ] }, { "uniprot_ac": "A0A8V0YDQ1", "gene_name": "WWP1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YDQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDQ1" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0YDQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDQ1" } ] } ] }, { "uniprot_ac": "A0A8V0YFD9", "gene_name": "UBE2D2", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0YFD9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFD9" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0YFD9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFD9" } ] } ] }, { "uniprot_ac": "A0A8V0YGF4", "gene_name": "MYLIP", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YGF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGF4" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YGF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGF4" } ] } ] }, { "uniprot_ac": "A0A8V0YHL7", "gene_name": "RNF114", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YHL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHL7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YHL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHL7" } ] } ] }, { "uniprot_ac": "A0A8V0YJK8", "gene_name": "RNF14", "activity": [ { "ec_number": "2.3.2.31", "activity": "[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.", "evidence": [ { "id": "A0A8V0YJK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJK8" } ] }, { "ec_number": "2.3.2.31", "activity": "", "evidence": [ { "id": "A0A8V0YJK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJK8" } ] } ] }, { "uniprot_ac": "A0A8V0YL05", "gene_name": "UBE3A", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YL05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL05" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0YL05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL05" } ] } ] }, { "uniprot_ac": "A0A8V0YLY7", "gene_name": "MKRN4P", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLY7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLY7" } ] } ] }, { "uniprot_ac": "A0A8V0YPW4", "gene_name": "UBE2J2", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0YPW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPW4" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0YPW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPW4" } ] } ] }, { "uniprot_ac": "A0A8V0YRM6", "gene_name": "RNF130", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YRM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRM6" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YRM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRM6" } ] } ] }, { "uniprot_ac": "A0A8V0YV22", "gene_name": "RNF4", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YV22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YV22" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YV22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YV22" } ] } ] }, { "uniprot_ac": "A0A8V0YVP3", "gene_name": "RBBP6", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YVP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVP3" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YVP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVP3" } ] } ] }, { "uniprot_ac": "A0A8V0YY10", "gene_name": "UBE2D3", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0YY10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YY10" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0YY10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YY10" } ] } ] }, { "uniprot_ac": "A0A8V0YYC5", "gene_name": "ZNRF2", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YYC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYC5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YYC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYC5" } ] } ] }, { "uniprot_ac": "A0A8V0Z082", "gene_name": "UBE2B", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0Z082", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z082" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0Z082", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z082" } ] } ] }, { "uniprot_ac": "A0A8V0Z1W7", "gene_name": "UBE2K", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0Z1W7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1W7" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0Z1W7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1W7" } ] } ] }, { "uniprot_ac": "A0A8V0Z2L5", "gene_name": "TRIM63", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Z2L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2L5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0Z2L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2L5" } ] } ] }, { "uniprot_ac": "A0A8V0Z4C8", "gene_name": "MGRN1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Z4C8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4C8" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0Z4C8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4C8" } ] } ] }, { "uniprot_ac": "A0A8V0Z596", "gene_name": "STUB1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Z596", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z596" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0Z596", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z596" } ] } ] }, { "uniprot_ac": "A0A8V0ZF21", "gene_name": "DTX3L", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZF21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF21" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZF21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF21" } ] } ] }, { "uniprot_ac": "A0A8V0ZJ49", "gene_name": "SMURF1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZJ49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ49" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZJ49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ49" } ] } ] }, { "uniprot_ac": "A0A8V0ZJV9", "gene_name": "MIB2", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZJV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJV9" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZJV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJV9" } ] } ] }, { "uniprot_ac": "A0A8V0ZKK3", "gene_name": "UBE3B", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKK3" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKK3" } ] } ] }, { "uniprot_ac": "A0A8V0ZKQ3", "gene_name": "RNF25", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZKQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKQ3" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZKQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKQ3" } ] } ] }, { "uniprot_ac": "A0A8V0ZL18", "gene_name": "HECTD2", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZL18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL18" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZL18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL18" } ] } ] }, { "uniprot_ac": "A0A8V0ZM17", "gene_name": "UBR1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZM17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM17" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZM17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM17" } ] } ] }, { "uniprot_ac": "A0A8V0ZS27", "gene_name": "TRIP12", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZS27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS27" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZS27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS27" } ] } ] }, { "uniprot_ac": "A0A8V0ZSA3", "gene_name": "HERC4", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZSA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSA3" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZSA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSA3" } ] } ] }, { "uniprot_ac": "A0A8V0ZSH4", "gene_name": "RNF111", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZSH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSH4" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZSH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSH4" } ] } ] }, { "uniprot_ac": "A0A8V0ZVX3", "gene_name": "NEDD4", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZVX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVX3" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZVX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVX3" } ] } ] }, { "uniprot_ac": "A0A8V0ZW26", "gene_name": "ZNRF1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZW26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZW26" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZW26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZW26" } ] } ] }, { "uniprot_ac": "A0A8V0ZZH3", "gene_name": "ITCH", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZZH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZH3" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZZH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZH3" } ] } ] }, { "uniprot_ac": "A0A8V1A052", "gene_name": "UBE2E3", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V1A052", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A052" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V1A052", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A052" } ] } ] }, { "uniprot_ac": "A0A8V1A0X2", "gene_name": "UBE3C", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A0X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0X2" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V1A0X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0X2" } ] } ] }, { "uniprot_ac": "A0A8V1A0Z6", "gene_name": "UBE4A", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A0Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Z6" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1A0Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Z6" } ] } ] }, { "uniprot_ac": "A0A8V1A1I4", "gene_name": "UBE2Z", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V1A1I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1I4" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V1A1I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1I4" } ] } ] }, { "uniprot_ac": "A0A8V1A1N8", "gene_name": "HERC1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A1N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1N8" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V1A1N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1N8" } ] } ] }, { "uniprot_ac": "A0A8V1A233", "gene_name": "RNF220", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A233", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A233" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1A233", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A233" } ] } ] }, { "uniprot_ac": "A0A8V1A2W7", "gene_name": "RNF41", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A2W7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2W7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1A2W7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2W7" } ] } ] }, { "uniprot_ac": "A0A8V1A4H7", "gene_name": "UBE2L3", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V1A4H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4H7" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V1A4H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4H7" } ] } ] }, { "uniprot_ac": "A0A8V1A5P4", "gene_name": "UBE2G2", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V1A5P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5P4" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V1A5P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5P4" } ] } ] }, { "uniprot_ac": "A0A8V1A7P9", "gene_name": "DCAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] } ] }, { "uniprot_ac": "A0A8V1A7T1", "gene_name": "RNF123", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A7T1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7T1" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1A7T1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7T1" } ] } ] }, { "uniprot_ac": "A0A8V1A9M0", "gene_name": "RNF34", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A9M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9M0" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1A9M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9M0" } ] } ] }, { "uniprot_ac": "A0A8V1AC19", "gene_name": "UBA7", "activity": [ { "ec_number": "6.2.1.45", "activity": "ATP + ubiquitin + [E1 ubiquitin-activating enzyme]-L-cysteine = AMP + diphosphate + S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V1AC19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC19" } ] }, { "ec_number": "6.2.1.45", "activity": "", "evidence": [ { "id": "A0A8V1AC19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC19" } ] } ] }, { "uniprot_ac": "A0A8V1AC55", "gene_name": "SMURF2", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1AC55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC55" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V1AC55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC55" } ] } ] }, { "uniprot_ac": "A0A8V1ACU3", "gene_name": "UBE2O", "activity": [ { "ec_number": "2.3.2.24", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E1 ubiquitin-activating enzyme]-L-cysteine + N(6)-monoubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1ACU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACU3" } ] }, { "ec_number": "2.3.2.24", "activity": "", "evidence": [ { "id": "A0A8V1ACU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACU3" } ] } ] }, { "uniprot_ac": "A0A8V1AKB8", "gene_name": "TRIM32", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1AKB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKB8" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1AKB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKB8" } ] } ] }, { "uniprot_ac": "A0A8V1AL09", "gene_name": "TRIM37", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1AL09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL09" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1AL09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL09" } ] } ] }, { "uniprot_ac": "A0A8V1ALH0", "gene_name": "RNF213", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1ALH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALH0" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1ALH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALH0" } ] } ] }, { "uniprot_ac": "A0A8V1AML5", "gene_name": "TRIM50", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1AML5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AML5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1AML5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AML5" } ] } ] }, { "uniprot_ac": "A0A8V1AP69", "gene_name": "TRIM58", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1AP69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP69" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1AP69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP69" } ] } ] }, { "uniprot_ac": "E1BZ35", "gene_name": "RNF182", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1BZ35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BZ35" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "E1BZ35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BZ35" } ] } ] }, { "uniprot_ac": "E1C3Q9", "gene_name": "SIAH2", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1C3Q9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C3Q9" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "E1C3Q9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C3Q9" } ] } ] }, { "uniprot_ac": "E1C656", "gene_name": "HACE1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1C656", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C656" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "E1C656", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C656" } ] } ] }, { "uniprot_ac": "E1C982", "gene_name": "AREL1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1C982", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C982" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "E1C982", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C982" } ] } ] }, { "uniprot_ac": "F1NC08", "gene_name": "RNF138", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1NC08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NC08" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "F1NC08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NC08" } ] } ] }, { "uniprot_ac": "F1NL19", "gene_name": "CDC34", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "F1NL19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NL19" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "F1NL19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NL19" } ] } ] }, { "uniprot_ac": "F1NL77", "gene_name": "CBLB", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1NL77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NL77" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "F1NL77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NL77" } ] } ] }, { "uniprot_ac": "F1NRC6", "gene_name": "RLIM", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1NRC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NRC6" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "F1NRC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NRC6" } ] } ] }, { "uniprot_ac": "F1NTZ8", "gene_name": "HECW2", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1NTZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NTZ8" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "F1NTZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NTZ8" } ] } ] }, { "uniprot_ac": "F1NVY8", "gene_name": "LNX1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1NVY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVY8" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "F1NVY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVY8" } ] } ] }, { "uniprot_ac": "F1P2G0", "gene_name": "SIAH1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1P2G0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P2G0" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "F1P2G0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P2G0" } ] } ] }, { "uniprot_ac": "Q5ZKX6", "gene_name": "UBE2F", "activity": [ { "ec_number": "2.3.2.34", "activity": "[E1 NEDD8-activating enzyme]-S-[NEDD8 protein]-yl-L-cysteine + [E2 NEDD8-conjugating enzyme]-L-cysteine = [E1 NEDD8-activating enzyme]-L-cysteine + [E2 NEDD8-conjugating enzyme]-S-[NEDD8-protein]-yl-L-cysteine.", "evidence": [ { "id": "Q5ZKX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKX6" } ] }, { "ec_number": "2.3.2.34", "activity": "", "evidence": [ { "id": "Q5ZKX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKX6" } ] } ] }, { "uniprot_ac": "R4GIV8", "gene_name": "UBE2R2", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "R4GIV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GIV8" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "R4GIV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GIV8" } ] } ] }, { "uniprot_ac": "Z4YJC3", "gene_name": "TRIM71", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": 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"sequence": "LSSLGKIARRVVFLSRMIAYYSAAISFCRGQRERRFSDVYSTCIQTHQRTTLGIVKAVWGAGVSIEEHTECWEKMEESFVASSTGEGMELINMVQQDETQRMKNSAVKNRLLYLTLSLNISIMVLFF", "length": 127, "header": "tr|A0A8V0ZSA4-1|A0A8V0ZSA4_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0ZSA4-1" }, "locus": { "chromosome": "1", "start_pos": 77850109, "end_pos": 77849522, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052764.1", "url": "https://www.ensembl.org/id/ENSGALT00010052764.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031670.1", "url": "https://www.ensembl.org/id/ENSGALP00010031670.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "fusion of sperm to egg plasma membrane involved in single fertilization", "id": "GO:0007342", "url": 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42211.0, "monoisotopic_mass": 42211.0 }, "refseq": { "ac": "XP_046775530", "name": "secretion-regulating guanine nucleotide exchange factor isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046775530" }, "gene_names": [ { "name": "SERGEF", "type": "recommended", "evidence": [ { "id": "A0A8V0ZSD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSD3" } ] }, { "name": "SERGEF", "type": "synonym", "evidence": [ { "id": "XP_046775530", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046775530" } ] } ], "protein_names": [ { "name": "Secretion regulating guanine nucleotide exchange factor", "type": "synonym", "evidence": [ { "id": "A0A8V0ZSD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSD3/entry#names_and_taxonomy" } ] }, { "name": "secretion-regulating guanine nucleotide exchange factor isoform X2", "type": "synonym", "evidence": [ { "id": "XP_046775530", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046775530" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052577.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_046775530", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046775530" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSD3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSD3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SERGEF", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSD3", "locus": { "chromosome": "5", "start_pos": 11931055, "end_pos": 12063386, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010024423", "url": "https://www.ensembl.org/id/ENSGALG00010024423" } ] } } ], "crossref": [ { "id": "A0A8V0ZSD3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZSD3", "database": "AlphaFoldDB", "categories": [] }, { "id": "423077", "url": "https://www.ncbi.nlm.nih.gov/gene/423077", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000408", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000408", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009091", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009091", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058923", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058923", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZSC3", "url": "https://www.orthodb.org/?gene=A0A8V0ZSC3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZSD3", "url": "https://www.orthodb.org/?gene=A0A8V0ZSD3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZXI0", "url": "https://www.orthodb.org/?gene=A0A8V0ZXI0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZZP1", "url": "https://www.orthodb.org/?gene=A0A8V0ZZP1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22870", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22870", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22870:SF408", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22870:SF408", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22870:SF466", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22870:SF466", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF25390", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25390", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_046775530", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046775530", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZSC3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSC3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZSC3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSC3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZSD3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSD3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZSD3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSD3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZXI0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXI0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZXI0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXI0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZZP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZP1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZZP1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZP1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEAVLRAWGANSYGQLGLGHKEDVLVPQLLKDVSCKCQDIKSIAGGGGHSAVITGAGELFVCGHNKAGQLGLNHTEDVLCFTLCTALSGFCVQEVACGWDFTIILGRAGLVLSCGSNAFGQLGVPQISGPCLIPQKIKSLKEKAVGIAAGLRHALAATESGLVFQWGTGMASRAKRVHQGKTLPVFWAAKEPCEIKGLEDVKVKRVAAGSYHCVSLTGEGHLYVWGSNKHGQLVSKEVFLVEPKKVDTQFFSHEKIGAVWSGWTHLVAQTETGKVFTWGRADYGQLGRHAVVPDGQETCTASEQPMKLFCNIPISLPCLNGASQIACGSEHNLAVVGDCCLSWGWNEHGMCGDGTEANVHVPKPVKALGYAKQILIGCGAGHSLALCQNSTLDSGHQKS", "length": 399, "header": "tr|A0A8V0ZSD3-1|A0A8V0ZSD3_CHICK Isoform 1 of Secretion regulating guanine nucleotide exchange factor OS=Gallus gallus OX=9031 GN=SERGEF PE=4 SV=1 CANONICAL=A0A8V0ZSD3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZSC3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSD3/entry#A0A8V0ZSC3-1", "sequence": { "sequence": "MEAVLRAWGANSYGQLGLGHKEDVLVPQLLKDVSCKCQDIKSIAGGGGHSAVITGAGELFVCGHNKAGQLGLNHTEDVLCFTLCTALSGFCVQEVACGWDFTIILGRAGLVLSCGSNAFGQLGVPQISGPCLIPQKIKSLKEKAVGIAAGLRHALAATESGLVFQWGTGMASRAKRVHQGKTLPVFWAAKEPCEIKGLEDVKVKRVAAGSYHCVSLTGEGHLYVWGSNKHGQLVSKEVFLVEPKKVDTQFFSHEKIGAVWSGWTHLVAQTETGKVFTWGRADYGQLGRHAVVPDGQETCTASEQPMKLFCNIPISLPCLNGASQIACGSEHNLAVVVLLTFKRKLERSGVKRKHMYGLGICRGG", "length": 364, "header": "tr|A0A8V0ZSC3-1|A0A8V0ZSD3_CHICK Computationally mapped isoform of Secretion regulating guanine nucleotide exchange factor OS=Gallus gallus OX=9031 GN=SERGEF PE=4 SV=1 CANONICAL=A0A8V0ZSD3-1" }, "locus": { "chromosome": "5", "start_pos": 12063345, "end_pos": 11941771, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010059582.1", "url": "https://www.ensembl.org/id/ENSGALT00010059582.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036383.1", "url": "https://www.ensembl.org/id/ENSGALP00010036383.1" } ] } }, { "isoform_ac": "A0A8V0ZSD3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSD3/entry#A0A8V0ZSD3-1", "sequence": { "sequence": "MEAVLRAWGANSYGQLGLGHKEDVLVPQLLKDVSCKCQDIKSIAGGGGHSAVITGAGELFVCGHNKAGQLGLNHTEDVLCFTLCTALSGFCVQEVACGWDFTIILGRAGLVLSCGSNAFGQLGVPQISGPCLIPQKIKSLKEKAVGIAAGLRHALAATESGLVFQWGTGMASRAKRVHQGKTLPVFWAAKEPCEIKGLEDVKVKRVAAGSYHCVSLTGEGHLYVWGSNKHGQLVSKEVFLVEPKKVDTQFFSHEKIGAVWSGWTHLVAQTETGKVFTWGRADYGQLGRHAVVPDGQETCTASEQPMKLFCNIPISLPCLNGASQIACGSEHNLAVVGDCCLSWGWNEHGMCGDGTEANVHVPKPVKALGYAKQILIGCGAGHSLALCQNSTLDSGHQKS", "length": 399, "header": "tr|A0A8V0ZSD3-1|A0A8V0ZSD3_CHICK Isoform 1 of Secretion regulating guanine nucleotide exchange factor OS=Gallus gallus OX=9031 GN=SERGEF PE=4 SV=1 CANONICAL=A0A8V0ZSD3-1" }, "locus": { "chromosome": "5", "start_pos": 12063345, "end_pos": 11933246, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010059593.1", "url": "https://www.ensembl.org/id/ENSGALT00010059593.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036394.1", "url": "https://www.ensembl.org/id/ENSGALP00010036394.1" } ] } }, { "isoform_ac": "A0A8V0ZXI0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSD3/entry#A0A8V0ZXI0-1", "sequence": { "sequence": "MQGANSYGQLGLGHKEDVLVPQLLKDVSCKCQDIKSIAGGGGHSAVITGAGELFVCGHNKAGQLGLNHTEDVLCFTLCTALSGFCVQEVACGWDFTIILGRAGLVLSCGSNAFGQLGVPQISGPCLIPQKIKSLKEKAVGIAAGLRHALAATESGLVFQWGTGMASRAKRVHQGKTLPVFWAAKEPCEIKGLEDVKVKRVAAGSYHCVSLTGEGHLYVWGSNKHGQLVSKEVFLVEPKKVDTQFFSHEKIGAVWSGWTHLVAQTETGKVFTWGRADYGQLGRHAVVPDGQETCTASEQPMKLFCNIPISLPCLNGASQIACGSEHNLAVVGDCCLSWGWNEHGMCGDGTEANVHVPKPVKALGYAKQILIGCGAGHSLALCQNSTLDSGHQKS", "length": 393, "header": "tr|A0A8V0ZXI0-1|A0A8V0ZSD3_CHICK Computationally mapped isoform of Secretion regulating guanine nucleotide exchange factor OS=Gallus gallus OX=9031 GN=SERGEF PE=4 SV=1 CANONICAL=A0A8V0ZSD3-1" }, "locus": { "chromosome": "5", "start_pos": 12062707, "end_pos": 11933246, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010059591.1", "url": "https://www.ensembl.org/id/ENSGALT00010059591.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036391.1", "url": "https://www.ensembl.org/id/ENSGALP00010036391.1" } ] } }, { "isoform_ac": "A0A8V0ZZP1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSD3/entry#A0A8V0ZZP1-1", "sequence": { "sequence": "MEAVLRAWGANSYGQLGLGHKEDVLVPQLLKDVSCKCQDIKSIAGGGGHSAVITGAGELFVCGHNKAGQLGLNHTEDVLCFTLCTALSGFCVQEVACGWDFTIILGRAGLVLSCGSNAFGQLGVPQISGPCLIPQKIKSLKEKAVGIAAGLRHALAATESGLVFQWGTGMASRAKRVHQGKTLPVFWAAKEPCEIKGLEDVKVKRVAAGSYHCVSLTGEGHLYVWGSNKHGQLVSKEVFLVEPKKVDTQFFSHEKIGAVWSGWTHLVAQTETGKVFTWGRADYGQLGRHAVVPDGQETCTASEQPMKLFCNIPISLPCLNGASQIACGSEHNLAVVAAPSALQVPAWIPVTVAYLGDGTNMGCVVMAQKQTFMYQSQ", "length": 377, "header": "tr|A0A8V0ZZP1-1|A0A8V0ZSD3_CHICK Computationally mapped isoform of Secretion regulating guanine nucleotide exchange factor OS=Gallus gallus OX=9031 GN=SERGEF PE=4 SV=1 CANONICAL=A0A8V0ZSD3-1" }, "locus": { "chromosome": "5", "start_pos": 12063345, "end_pos": 11933350, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010059586.1", "url": "https://www.ensembl.org/id/ENSGALT00010059586.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036387.1", "url": "https://www.ensembl.org/id/ENSGALP00010036387.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "negative regulation of protein secretion", "id": "GO:0050709", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050709", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSD3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSD3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSD3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSD3" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSD3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSD3" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSD3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSD3" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSD3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSD3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 389, "end_pos": 391, "annotation": "n_glycosylation_sequon" }, { "start_pos": 73, "end_pos": 75, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZSD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSD3" }, { "id": "PF25390", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25390" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RCC1-like", "eco_id": "ECO_0000259", "start_pos": 6, "end_pos": 385, "start_aa": "Arg", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 389, "end_pos": 391 }, { "start_pos": 73, "end_pos": 75 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZSC8-1", "uniprot_ac": "A0A8V0ZSC8", "uniprot_id": "A0A8V0ZSC8_CHICK", "mass": { "chemical_mass": 50707.0, "monoisotopic_mass": 50707.0 }, "refseq": {}, "gene_names": [ { "name": "NUCB2", "type": "recommended", "evidence": [ { "id": "A0A8V0ZSC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSC8" } ] } ], "protein_names": [ { "name": "Nucleobindin 2", "type": "synonym", "evidence": [ { "id": "A0A8V0ZSC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSC8/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSC8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NUCB2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSC8", "locus": { "chromosome": "5", "start_pos": 11464036, "end_pos": 11435177, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010023238", "url": "https://www.ensembl.org/id/ENSGALG00010023238" } ] } } ], "crossref": [ { "id": "A0A8V0ZSC8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZSC8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000006147", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000006147", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "423071", "url": "https://www.ncbi.nlm.nih.gov/gene/423071", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002048", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002048", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018247", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018247", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040250", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040250", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057576", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057576", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:423071", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423071", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QETDTNH", "url": "https://omabrowser.org/oma/group/QETDTNH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZM33", "url": "https://www.orthodb.org/?gene=A0A8V0ZM33", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZSC8", "url": "https://www.orthodb.org/?gene=A0A8V0ZSC8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZSE1", "url": "https://www.orthodb.org/?gene=A0A8V0ZSE1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZUD1", "url": "https://www.orthodb.org/?gene=A0A8V0ZUD1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NGB1", "url": "https://www.orthodb.org/?gene=F1NGB1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19237", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19237", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19237:SF22", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19237:SF22", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13499", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13499", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25434", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25434", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZM33", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM33", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZM33-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM33-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZSC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSC8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZSC8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSC8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZSE1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSE1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZSE1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSE1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZUD1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUD1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZUD1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUD1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NGB1", "url": "https://www.uniprot.org/uniprotkb/F1NGB1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NGB1-1", "url": "https://www.uniprot.org/uniprotkb/F1NGB1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKWQSLLPQQCILLIPCLLMALEAVPIDIDKTKVKGEGHVEGEKIENPDTGLYYDEYLRQVIDVLETDKHFREKLQTADIEEIKSGKLSRELDLVSHHVRTRLDELKRQEVARLRMLIKAKMDSVQDTGIDHQALLKQFEHLNHQNPDTFEPKDLDMLIKAATSDLENYDKTRHEEFKKYEMMKEHERREYLKTLDEEKRQREESKFEEMKKKHGDHPKVHHPGSKDQLKEVWEEADGLDPNEFDPKTFFKLHDVNNDRFLDEQELEALFTKELEKVYDPKNEEDDMVEMEEERLRMREHVMNEVDINKDRLVTLEEFLRATEKKEFLEPDSWETLDQQQLFTEDELKEFESHISQQEDELRKKAEELQKQKEELQRQHDQLQAQKQELQQEAEVCFHNFLLRELDIVTAATRVTSFPSAESWL", "length": 424, "header": "tr|A0A8V0ZSC8-1|A0A8V0ZSC8_CHICK Isoform 1 of Nucleobindin 2 OS=Gallus gallus OX=9031 GN=NUCB2 PE=1 SV=1 CANONICAL=A0A8V0ZSC8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZM33-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSC8/entry#A0A8V0ZM33-1", "sequence": { "sequence": "MKWQSLLPQQCILLIPCLLMALEAVPIDIDKTKVKGEGHVEGEKIENPDTGLYYDEYLRQVIDVLETDKHFREKLQTADIEEIKSGKLSRELDLVSHHVRTRLDELKRQEVARLRMLIKAKMDSVQDTGIDHQALLKQFEHLNHQNPDTFEPKDLDMLIKAATSDLENYDKTRHEEFKKYEMMKEHERREYLKTLDEEKRQREESKFEEMKKKHGDHPKVHHPGSKDQLKEVWEEADGLDPNEFDPKTFFKLHDVNNDRFLDEQELEALFTKEVDINKDRLVTLEEFLRATEKKEFLEPDSWETLDQQQLFTEDELKEFESHISQQEDELRKKAEELQKQKEELQRQHDQLQAQKQELQQVVKQMEQKKLQQANPPAGPAGELKFQPPGEHKIEEAPKHPAGGDQPLPPGHIQEPAARTDQVHP", "length": 424, "header": "tr|A0A8V0ZM33-1|A0A8V0ZM33_CHICK Computationally mapped isoform of Nucleobindin 2 OS=Gallus gallus OX=9031 GN=NUCB2 PE=1 SV=1 CANONICAL=A0A8V0ZSC8-1" }, "locus": { "chromosome": "5", "start_pos": 11460319, "end_pos": 11444520, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056698.1", "url": "https://www.ensembl.org/id/ENSGALT00010056698.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034440.1", "url": "https://www.ensembl.org/id/ENSGALP00010034440.1" } ] } }, { "isoform_ac": "A0A8V0ZSC8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSC8/entry#A0A8V0ZSC8-1", "sequence": { "sequence": "MKWQSLLPQQCILLIPCLLMALEAVPIDIDKTKVKGEGHVEGEKIENPDTGLYYDEYLRQVIDVLETDKHFREKLQTADIEEIKSGKLSRELDLVSHHVRTRLDELKRQEVARLRMLIKAKMDSVQDTGIDHQALLKQFEHLNHQNPDTFEPKDLDMLIKAATSDLENYDKTRHEEFKKYEMMKEHERREYLKTLDEEKRQREESKFEEMKKKHGDHPKVHHPGSKDQLKEVWEEADGLDPNEFDPKTFFKLHDVNNDRFLDEQELEALFTKELEKVYDPKNEEDDMVEMEEERLRMREHVMNEVDINKDRLVTLEEFLRATEKKEFLEPDSWETLDQQQLFTEDELKEFESHISQQEDELRKKAEELQKQKEELQRQHDQLQAQKQELQQEAEVCFHNFLLRELDIVTAATRVTSFPSAESWL", "length": 424, "header": "tr|A0A8V0ZSC8-1|A0A8V0ZSC8_CHICK Isoform 1 of Nucleobindin 2 OS=Gallus gallus OX=9031 GN=NUCB2 PE=1 SV=1 CANONICAL=A0A8V0ZSC8-1" }, "locus": { "chromosome": "5", "start_pos": 11462287, "end_pos": 11444520, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056705.1", "url": "https://www.ensembl.org/id/ENSGALT00010056705.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034447.1", "url": "https://www.ensembl.org/id/ENSGALP00010034447.1" } ] } }, { "isoform_ac": "A0A8V0ZSE1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSC8/entry#A0A8V0ZSE1-1", "sequence": { "sequence": "MPKMKWQSLLPQQCILLIPCLLMALEAVPIDIDKTKVKGEGHVEGEKIENPDTGLYYDEYLRQVIDVLETDKHFREKLQTADIEEIKSGKLSRELDLVSHHVRTRLDELKRQEVARLRMLIKAKMDSVQDTGIDHQALLKQFEHLNHQNPDTFEPKDLDMLIKAATSDLENYDKTRHEEFKKYEMMKEHERREYLKTLDEEKRQREESKFEEMKKKHGDHPKVHHPGSKDQLKEVWEEADGLDPNEFDPKTFFKLHDVNNDRFLDEQELEALFTKELEKVYDPKNEEDDMVEMEEERLRMREHVMNEVDINKDRLVTLEEFLRATEKKEFLEPDSWETLDQQQLFTEDELKEFESHISQQEDELRKKAEELQKQKEELQRQHDQLQAQKQELQQVVKQMEQKKLQQANPPAGPAGELKFQPPGEHKIEEAPKHPAGGDQPLPPGHIQEPAARTDQVHP", "length": 458, "header": "tr|A0A8V0ZSE1-1|A0A8V0ZSE1_CHICK Computationally mapped isoform of Nucleobindin 2 OS=Gallus gallus OX=9031 GN=NUCB2 PE=1 SV=1 CANONICAL=A0A8V0ZSC8-1" }, "locus": { "chromosome": "5", "start_pos": 11460319, "end_pos": 11441401, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056721.1", "url": "https://www.ensembl.org/id/ENSGALT00010056721.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034463.1", "url": "https://www.ensembl.org/id/ENSGALP00010034463.1" } ] } }, { "isoform_ac": "A0A8V0ZUD1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSC8/entry#A0A8V0ZUD1-1", "sequence": { "sequence": "MKWQSLLPQQCILLIPCLLMALEAVPIDIDKTKVKGEGHVEGEKIENPDTGLYYDEYLRQVIDVLETDKHFREKLQTADIEEIKSGKLSRELDLVSHHVRTRLDELKRQEVARLRMLIKAKMDSVQDTGIDHQALLKQFEHLNHQNPDTFEPKDLDMLIKAATSDLENYDKTRHEEFKKYEMMKEHERREYLKTLDEEKRQREESKFEEMKKKHGDHPKVHHPGSKDQLKEVWEEADGLDPNEFDPKTFFKLHDVNNDRFLDEQELEALFTKELEKVYDPKNEEDDMVEMEEERLRMREHVMNEVDINKDRLVTLEEFLRATEKKEFLEPDSWETLDQQQHDQLQAQKQELQQVVKQMEQKKLQQANPPAGPAGELKFQPPGEHKIEEAPKHPAGGDQPLPPGHIQEPAARTDQVHP", "length": 417, "header": "tr|A0A8V0ZUD1-1|A0A8V0ZUD1_CHICK Computationally mapped isoform of Nucleobindin 2 OS=Gallus gallus OX=9031 GN=NUCB2 PE=1 SV=1 CANONICAL=A0A8V0ZSC8-1" }, "locus": { "chromosome": "5", "start_pos": 11460319, "end_pos": 11444520, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056713.1", "url": "https://www.ensembl.org/id/ENSGALT00010056713.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034455.1", "url": "https://www.ensembl.org/id/ENSGALP00010034455.1" } ] } }, { "isoform_ac": "F1NGB1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSC8/entry#F1NGB1-1", "sequence": { "sequence": "MKWQSLLPQQCILLIPCLLMALEAVPIDIDKTKVKGEGHVEGEKIENPDTGLYYDEYLRQVIDVLETDKHFREKLQTADIEEIKSGKLSRELDLVSHHVRTRLDELKRQEVARLRMLIKAKMDSVQDTGIDHQALLKQFEHLNHQNPDTFEPKDLDMLIKAATSDLENYDKTRHEEFKKYEMMKEHERREYLKTLDEEKRQREESKFEEMKKKHGDHPKVHHPGSKDQLKEVWEEADGLDPNEFDPKTFFKLHDVNNDRFLDEQELEALFTKELEKVYDPKNEEDDMVEMEEERLRMREHVMNEVDINKDRLVTLEEFLRATEKKEFLEPDSWETLDQQQLFTEDELKEFESHISQQEDELRKKAEELQKQKEELQRQHDQLQAQKQELQQVVKQMEQKKLQQANPPAGPAGELKFQPPGEHKIEEAPKHPAGGDQPLPPGHIQEPAARTDQVHP", "length": 455, "header": "tr|F1NGB1-1|A0A8V0ZSC8_CHICK Computationally mapped isoform of Nucleobindin 2 OS=Gallus gallus OX=9031 GN=NUCB2 PE=1 SV=1 CANONICAL=A0A8V0ZSC8-1" }, "locus": { "chromosome": "5", "start_pos": 11460319, "end_pos": 11444520, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056709.1", "url": "https://www.ensembl.org/id/ENSGALT00010056709.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034451.1", "url": "https://www.ensembl.org/id/ENSGALP00010034451.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:423071", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423071", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0AAA9U1W7-1", "protein_name": "Nucleobindin 2", "gene_name": "NUCB2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MKWRTILPQCCLLLVTCALPALESVPIDIDKTKVKTTQPVDSAKIEPPDTGLYYDEYLKQVIDVLETDSHFREKLQKADIEEIKSGRLSKELDLVSHHVRTKLDELKRQEVARLRMLIKAKLDSFQDTGMDHHALLKQFDHLNHLNPDKFESTDLDMLIKAATSDLEHYDKARHEEFKKYEMMKEHERREYLKTLSEEKRKEEESKFAEMKKKHENHPKVNHPGSKDQLKEVWEEADGLDPNDFDPKTFFKLHDVNSDGFLDEQELEALFTKELEKVYDPKNEEDDMVEMEEERLRMREHVMNEVDTNKDRLVTLDEFLKATEKKEFLEPDSWETLDHQQFFTEEELKEYENLISVQESKLKKKADELQKQKEDLQRQHDQLEAQKLEYHQVVFCKMLVALKRILGSLLHASVLVL", "length": 416 }, "evidence": [ { "id": "A0A8V0ZSC8", "url": "https://omabrowser.org/oma/group/A0A8V0ZSC8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1S9A4-1", "protein_name": "EF-hand domain-containing protein", "gene_name": "NUCB2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAARRRERAVGRSAEQSRRLGAGEAGLCAANIQQAEPRAWFSRLRKAGGLEMKWRTILLQYWFFLVTYVFTALEAVPIDIDKTKVKNTQPVDSAKIEPPDTGLYYDEYLKQVIDVLETDNHFREKLQKADIEEIKSGRLSRELDLVSHHVRTKLDELKRQEVARLRMLIKAKLDSLQDTGIDHHALLKQFDHLNHLNPDKFESTDLDMLIKAATSDLEHYDKARHEEFKKYEMMKEHERREYLKTLTEEKRKEEESKFEEMKKKHGNHPKVNHPGSKDQLKEVWEETDGLDPNDFDPKTFFKLHDVNGDGFLDEQELEALFTKELEKVYDPKNEEDDMVEMEEERLRMREHVMNEVDTNKDRLVTLEEFLKATEKREFLEPDSWETLDQQQFFTEEELKEYENLISVQETELKKKADELQKQKEELQRQHDQLEAQKLEYHQVVQQMEQKKLQAISPSALVENQRSSHTFEA", "length": 472 }, "evidence": [ { "id": "A0A8V0ZSC8", "url": "https://omabrowser.org/oma/group/A0A8V0ZSC8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P80303-1", "protein_name": "Nucleobindin-2", "gene_name": "NUCB2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRWRTILLQYCFLLITCLLTALEAVPIDIDKTKVQNIHPVESAKIEPPDTGLYYDEYLKQVIDVLETDKHFREKLQKADIEEIKSGRLSKELDLVSHHVRTKLDELKRQEVGRLRMLIKAKLDSLQDIGMDHQALLKQFDHLNHLNPDKFESTDLDMLIKAATSDLEHYDKTRHEEFKKYEMMKEHERREYLKTLNEEKRKEEESKFEEMKKKHENHPKVNHPGSKDQLKEVWEETDGLDPNDFDPKTFFKLHDVNSDGFLDEQELEALFTKELEKVYDPKNEEDDMVEMEEERLRMREHVMNEVDTNKDRLVTLEEFLKATEKKEFLEPDSWETLDQQQFFTEEELKEYENIIALQENELKKKADELQKQKEELQRQHDQLEAQKLEYHQVIQQMEQKKLQQGIPPSGPAGELKFEPHI", "length": 420 }, "evidence": [ { "id": "A0A8V0ZSC8", "url": "https://omabrowser.org/oma/group/A0A8V0ZSC8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P81117-1", "protein_name": "Nucleobindin-2", "gene_name": "Nucb2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRWRIIQVQYCFLLVPCMLTALEAVPIDVDKTKVHNTEPVENARIEPPDTGLYYDEYLKQVIEVLETDPHFREKLQKADIEEIRSGRLSQELDLVSHKVRTRLDELKRQEVGRLRMLIKAKLDALQDTGMNHHLLLKQFEHLNHQNPNTFESRDLDMLIKAATADLEQYDRTRHEEFKKYEMMKEHERREYLKTLSEEKRKEEESKFEEMKRKHEDHPKVNHPGSKDQLKEVWEETDGLDPNDFDPKTFFKLHDVNNDGFLDEQELEALFTRELEKVYNPQNAEDDMIEMEEERLRMREHVMSEIDNNKDRLVTLEEFLRATEKKEFLEPDSWETLDQQQLFTEDELKEYESIIAIQENELKKRAEELQKQKEDLQRQHDHLEAQKQEYHQAVQHLEQKKLQQGIAPSGPAGELKFEPHT", "length": 420 }, "evidence": [ { "id": "A0A8V0ZSC8", "url": "https://omabrowser.org/oma/group/A0A8V0ZSC8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9JI85-1", "protein_name": "Nucleobindin-2", "gene_name": "Nucb2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRWRTIQARYCFLLVPCVLTALEAVPIDVDKTKVHNVEPVESARIEPPDTGLYYDEYLKQVIEVLETDPHFREKLQKADIEEIRSGRLSQELDLVSHKVRTRLDELKRQEVGRLRMLIKAKLDALQDTGMNHHLLLKQFEHLNHQNPDTFESKDLDMLIKAATADLEQYDRTRHEEFKKYEMMKEHERREYLKTLSEEKRKEEEAKFAEMKRKHEDHPKVNHPGSKDQLKEVWEETDGLDPNDFDPKTFFKLHDVNNDGFLDEQELEALFTKELDKVYNPQNAEDDMIEMEEERLRMREHVMNEIDNNKDRLVTLEEFLRATEKKEFLEPDSWETLDQQQLFTEEELKEYESIIAIQESELKKKADELQKQKEELQRQHDHLEAQKQEYQQAVQQLEQKKFQQGIAPSGPAGELKFEPHT", "length": 420 }, "evidence": [ { "id": "A0A8V0ZSC8", "url": "https://omabrowser.org/oma/group/A0A8V0ZSC8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9VVK7-1", "protein_name": "Nucleobindin", "gene_name": "NUCB1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MVQNVALLGLALIAISASIVALPVTQNKKDHKEAAESSTPATADVETALEYERYLREVVEALEADPEFRKKLDKAPEADIRSGKIAQELDYVNHHVRTKLDEIKRREVERLRELANQAYELSNDIDRKHLKVSQHLDHDNEHTFEIEDLRKLIQKTSDDLAEADRKRRGEFKEYEMQKEFEREAQKKEMDEESRKKFETELKEKEEKHKDHEKLHHPGNKAQLEDVWEKQDHMDKNDFDPKTFFSIHDVDSNGYWDEAEVKALFVKELDKVYQSDLPEDDMRERAEEMERMREHYFQETDMNHDGLISIDEFMVQTNKEEFQKDPEWETIDRQQQYTHEEYLEYERRRQEEVQRLIAQGQLPPHPNMPQGYYAAPPPGGVAYQQAPPGAQLHYQHPDQVHAQQQQQYAQQQQQYAQQYQQQQYGNGQQPVQLQPNQVYQHAGQIPQQQQPVYQNQPVYQQQQPVYQQQQPVQQQQKPVQQPVQQQQQPVQQQQQPVQQQQQTVQQQQPVQQQQQTVQQQQPVQQQQQTAQQQPVAQQQIHNQSPPPVLNQQVPVQQQQKQHQESLNQQH", "length": 569 }, "evidence": [ { "id": "A0A8V0ZSC8", "url": "https://omabrowser.org/oma/group/A0A8V0ZSC8/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSC8" } ], "pmid": "" }, { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSC8" } ], "pmid": "" }, { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSC8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSC8" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSC8" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSC8" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSC8" } ], "pmid": "" }, { "name": "endoplasmic reticulum-Golgi intermediate compartment", "id": "GO:0005793", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005793", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSC8" } ], "pmid": "" }, { "name": "nuclear outer membrane", "id": "GO:0005640", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005640", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSC8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZSC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSC8" }, { "id": "PS50222", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50222" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EF-hand", "eco_id": "ECO_0000259", "start_pos": 241, "end_pos": 276, "start_aa": "Pro", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZSD9-1", "uniprot_ac": "A0A8V0ZSD9", "uniprot_id": "A0A8V0ZSD9_CHICK", "mass": { "chemical_mass": 56294.0, "monoisotopic_mass": 56294.0 }, "refseq": { "ac": "XP_417363", "name": "recombining binding protein suppressor of hairless-like protein isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417363" }, "gene_names": [ { "name": "RBPJL", "type": "recommended", "evidence": [ { "id": "A0A8V0ZSD9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSD9" } ] }, { "name": "RBPJL", "type": "synonym", "evidence": [ { "id": "XP_417363", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417363" } ] } ], "protein_names": [ { "name": "Recombining binding protein suppressor of hairless-like protein", "type": "recommended", "evidence": [ { "id": "A0A8V0ZSD9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSD9/entry#names_and_taxonomy" } ] }, { "name": "Transcription factor RBP-L", "type": "synonym", "evidence": [ { "id": "A0A8V0ZSD9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSD9/entry#names_and_taxonomy" } ] }, { "name": "recombining binding protein suppressor of hairless-like protein isoform X1", "type": "synonym", "evidence": [ { "id": "XP_417363", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417363" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052551.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_417363.3. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_417363", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417363" } ] }, { "annotation": "Putative transcription factor, which cooperates with EBNA2 to activate transcription.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLM4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLM4#function" }, { "database": "UniProtKB", "id": "ARBA00055625", "url": "https://www.uniprot.org/uniprotkb/ARBA00055625#function" }, { "database": "UniProtKB", "id": "A0A8V0ZSD9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSD9#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSD9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSD9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RBPJL", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSD9", "locus": { "chromosome": "20", "start_pos": 5490403, "end_pos": 5503706, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021729", "url": "https://www.ensembl.org/id/ENSGALG00010021729" } ] } } ], "crossref": [ { "id": "A0A8V0ZSD9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZSD9", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd01176", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01176", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "419185", "url": "https://www.ncbi.nlm.nih.gov/gene/419185", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR008967", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008967", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014756", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014756", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015350", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015350", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015351", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015351", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036358", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036358", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037095", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037095", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038007", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038007", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040159", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040159", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "VQGEHFH", "url": "https://omabrowser.org/oma/group/VQGEHFH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZLM4", "url": "https://www.orthodb.org/?gene=A0A8V0ZLM4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZSD9", "url": "https://www.orthodb.org/?gene=A0A8V0ZSD9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10665", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10665", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF09270", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09270", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF09271", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09271", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF20144", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20144", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_417363", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417363", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLM4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLM4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLM4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLM4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZSD9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSD9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZSD9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSD9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDPQRQAGADAAEPLTHPYRPRSRSPPRCWLRSNPYQADLLRDGVRRYLQLPAEQTVLILHAKVAQKSYGNEKRFFCPPPCVYLGGPGWKLKQEQLTARDVGEAGLRVWGYMGLDTMGSSLMETQKLSFEEQPDAKGFGCAKALYISDADKCKHFRLVLKLFFSNGQEIGTFHSKLIKVISKPSQKKQSLKNTDLCISSGSKVSLFNRLRSQTVSTRYLSVEGGAFIASARQWAAFTLHLADERCTRSEFPLREGYIRYGSVVQLICTATGITLPPLIIRKVSKQYAMLDVDEPISQLHKCAFQFQGSDHMYLCLSTEKVIQFQASPCPKEANRELLNDGSCWTIIGTETVEYSFSESLACAREPVSPVPLITALQLSGGGDVAMLEVQGEHFHAHLKVWFGDVEAETMYRSPKSLMCVVPDVSAFSSDWRWLRYPITVPLLLVRDDGLIYSSSFTFTYTPEQSFLPGQQLPADVPQDSDALLNSIHQEFTRTNFHLFMQS", "length": 501, "header": "tr|A0A8V0ZSD9-1|A0A8V0ZSD9_CHICK Isoform 1 of Recombining binding protein suppressor of hairless-like protein OS=Gallus gallus OX=9031 GN=RBPJL PE=3 SV=1 CANONICAL=A0A8V0ZSD9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZLM4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSD9/entry#A0A8V0ZLM4-1", "sequence": { "sequence": "MCSGADAAEPLTHPYRPRSRSPPRCWLRSNPYQADLLRDGVRRYLQLPAEQTVLILHAKVAQKSYGNEKRFFCPPPCVYLGGPGWKLKQEQLTARDVGEAGLRVWGYMGLDTMGSSLMETQKLSFEEQPDAKGFGCAKALYISDADKCKHFRLVLKLFFSNGQEIGTFHSKLIKVISKPSQKKQSLKNTDLCISSGSKVSLFNRLRSQTVSTRYLSVEGGAFIASARQWAAFTLHLADERCTRSEFPLREGYIRYGSVVQLICTATGITLPPLIIRKVSKQYAMLDVDEPISQLHKCAFQFQGSDHMYLCLSTEKVIQFQASPCPKEANRELLNDGSCWTIIGTETVEYSFSESLACAREPVSPVPLITALQLSGGGDVAMLEVQGEHFHAHLKVWFGDVEAETMYRSPKSLMCVVPDVSAFSSDWRWLRYPITVPLLLVRDDGLIYSSSFTFTYTPEQSFLPGQQLPADVPQDSDALLNSIHQEFTRTNFHLFMQS", "length": 497, "header": "tr|A0A8V0ZLM4-1|A0A8V0ZLM4_CHICK Computationally mapped isoform of Recombining binding protein suppressor of hairless-like protein OS=Gallus gallus OX=9031 GN=RBPJL PE=3 SV=1 CANONICAL=A0A8V0ZSD9-1" }, "locus": { "chromosome": "20", "start_pos": 5498115, "end_pos": 5490721, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052803.1", "url": "https://www.ensembl.org/id/ENSGALT00010052803.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031709.1", "url": "https://www.ensembl.org/id/ENSGALP00010031709.1" } ] } }, { "isoform_ac": "A0A8V0ZSD9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSD9/entry#A0A8V0ZSD9-1", "sequence": { "sequence": "MDPQRQAGADAAEPLTHPYRPRSRSPPRCWLRSNPYQADLLRDGVRRYLQLPAEQTVLILHAKVAQKSYGNEKRFFCPPPCVYLGGPGWKLKQEQLTARDVGEAGLRVWGYMGLDTMGSSLMETQKLSFEEQPDAKGFGCAKALYISDADKCKHFRLVLKLFFSNGQEIGTFHSKLIKVISKPSQKKQSLKNTDLCISSGSKVSLFNRLRSQTVSTRYLSVEGGAFIASARQWAAFTLHLADERCTRSEFPLREGYIRYGSVVQLICTATGITLPPLIIRKVSKQYAMLDVDEPISQLHKCAFQFQGSDHMYLCLSTEKVIQFQASPCPKEANRELLNDGSCWTIIGTETVEYSFSESLACAREPVSPVPLITALQLSGGGDVAMLEVQGEHFHAHLKVWFGDVEAETMYRSPKSLMCVVPDVSAFSSDWRWLRYPITVPLLLVRDDGLIYSSSFTFTYTPEQSFLPGQQLPADVPQDSDALLNSIHQEFTRTNFHLFMQS", "length": 501, "header": "tr|A0A8V0ZSD9-1|A0A8V0ZSD9_CHICK Isoform 1 of Recombining binding protein suppressor of hairless-like protein OS=Gallus gallus OX=9031 GN=RBPJL PE=3 SV=1 CANONICAL=A0A8V0ZSD9-1" }, "locus": { "chromosome": "20", "start_pos": 5503526, "end_pos": 5490721, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052806.1", "url": "https://www.ensembl.org/id/ENSGALT00010052806.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031711.1", "url": "https://www.ensembl.org/id/ENSGALP00010031711.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 438, "start_aa": "Thr", "end_pos": 438, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr438", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A287BMW1-1", "protein_name": "Recombining binding protein suppressor of hairless-like protein", "gene_name": "RBPJL", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDPVGADPSGPPGPLTHLSLPDSSEARPQSGADGRSLRGSWTRSSPEPAALLREGVRWCLQQQCEQTVRILHAKVAQKSYGNEKRFFCPPPCVYLAGPGWRVKPLQGQAHQAGETGPMVCGYMGLDGASGSAAETQKLNFEEQPDSREFGCAKTLYISDADKRKNFRLVLRLVLRGGRELGTFHSRLIKVISKPSQKKQSLKNTDLCISSGSKVSLFNRLRSQTVSTRYLSVEDGDFVASARQWAAFTLHLADEHSSQGDFPPREGYIRYGSLVQLVCTVSGITLPPMIIRKVAKQCALLDVDEPISQLHKCAFQFPGGPPGGGGTYLCLATEKVVQFQASPCPKEANKALLNDSSCWTIIGTESVEFSFSTSLACTREPVTPVPLISTLELSGGGDVATLELHGENFHAGLKVWFGDVEAETMFRSPRSLVCVVPDVAAFGSDWRWLRTPITVPLSLVRADGLFYPSAFSFTYTPEYSARPGPPGAPAPAADPDELLESIHHEFTRTNFHLFIQT", "length": 516 }, "evidence": [ { "id": "A0A8V0ZSD9", "url": "https://omabrowser.org/oma/group/A0A8V0ZSD9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "D4AEG0-1", "protein_name": "Recombining binding protein suppressor of hairless-like protein", "gene_name": "Rbpjl", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNPGETTDPSVPPGPLTHLSLPDSSEVRLQNDGPSLLGSWTRSPPEHATILREGVRTCLQQRCEQTVWILHAKVAQKSYGTEKRFFCPPPCVYLAGPGWRVKPMQDQVHQSADTGPTVCGYMGLDGASGSAPETQKLNFEEQPDSREFGCAKTLFISDADKRKHFRLVLRLVQRGGRELGTFHSRLIKVISKPSQKKQSLKNTDLCISSGSKVSLFNRLRSQTVSTRYLSVEDGAFVASARQWAAFTLHLADGHCSQGDFPPQEGYIRYGSLVQLVCTVTGITLPPMIIRKVAKQCALLDVDEPISQLHKCAFQFPGDTPGGAGTYLCLSTEKVVRFQASLCPKEANRALLNDSSCWTIIGTESVEFSFSTSLACTPEPVTPVPHISTLELSGGGDVATLELHGENFHAGLKVWFGDVEAETMYRSPRSLVCVVPDVAAFGSDWRWLRTPITVPVSLLRADALFYPSAFSFTYTPEYSTRPRPPNAQEPAPDADALLESIHHEFTRTNFHLFCPT", "length": 515 }, "evidence": [ { "id": "A0A8V0ZSD9", "url": "https://omabrowser.org/oma/group/A0A8V0ZSD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1BDE8-1", "protein_name": "Recombining binding protein suppressor of hairless-like protein", "gene_name": "RBPJL", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MDPVGADPSAPPGPLTHLSLPDSSEARPQSGADGRSLPGSWTRSSSEPSAVLREGVRRCLQQQCEQTVWILHAKVAQKSYGNEKRFFCPPPCVYLAGPGWRVKPVPGQAHQAGQTGPLVCGYMGLDGASGSAAETQKLNFEEQPDSREFSCAKTLYISDADKRKHFRLVLRLMLRGGRELGTFHSRLIKVISKPSQKKQSLKNTDLCISSGSKVSLFNRLRSQTVSTRYLSVEDGDFVASARQWAAFTLHLADEQCSQGDFPPREGYVRYGSLVQLVCTVTGITLPPMIIRKVAKQCALLDVDEPISQLHKCAFQFPGGPPGGGGTYLCLATEKVVQFQASPCPNEANRALLNDNSCWTIIGTESVEFSFSTSLACTREPVTPVPLISTLELSGGGDVATLELHGENFHAGLKVWFGDVEAETMYRSPRSLVCVVPDVAVFGSDWRWLRTPITVPVSLVRTDGLFYPSAFSFTYTPEYSARPGAPGALAAPAADADALLESIHHEFTRTNFHLFIQT", "length": 517 }, "evidence": [ { "id": "A0A8V0ZSD9", "url": "https://omabrowser.org/oma/group/A0A8V0ZSD9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "O08674-1", "protein_name": "Recombining binding protein suppressor of hairless-like protein", "gene_name": "Rbpjl", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDPRETTDPSLPPGPLTHLSLPDSSEVRLQSDGPSLLGSWTRSPPEHAIILREGVRTCLQQRCEQTVWILHAKVAQKSYGNEKRFFCPPPCVYLAGPGWRVKPMQDQALQSAETGPTVCGYMGLDGASGSAPETQKLNFEEQPDSREFGCAKTLYISDADKRKHFRLVLRLVLRGGQELGTFHSRLIKVISKPSQKKQSLKNTDLCISSGSKVSLFNRLRSQTVSTRYLSVEDGAFVASARQWAAFTLHLADGHCSQGDFPPQEGYIRYGSLVQLVCTVTGITLPPMIIRKVAKQCALLDVDEPISQLHKCAFQFPSDTPGGAGTYLCLATEKVVRFQASLCPKEANRALLNDSSCWTIIGTESVEFTFSTSLACTREPVTPVPLISTLELSGGGDVATLELHGENFHAGLKVWFGDVEAETMYRSPRSLVCVVPDVAAFGSDWRWLRTPITVPVSLLRADALFYPSPFSFTYTPEYSALPRLPNAQEPAPDADTLLESIHHEFTRTNFHLFCPT", "length": 515 }, "evidence": [ { "id": "A0A8V0ZSD9", "url": "https://omabrowser.org/oma/group/A0A8V0ZSD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9UBG7-1", "protein_name": "Recombining binding protein suppressor of hairless-like protein", "gene_name": "RBPJL", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDPAGAADPSVPPNPLTHLSLQDRSEMQLQSEADRRSLPGTWTRSSPEHTTILRGGVRRCLQQQCEQTVRILHAKVAQKSYGNEKRFFCPPPCVYLSGPGWRVKPGQDQAHQAGETGPTVCGYMGLDSASGSATETQKLNFEQQPDSREFGCAKTLYISDADKRKHFRLVLRLVLRGGRELGTFHSRLIKVISKPSQKKQSLKNTDLCISSGSKVSLFNRLRSQTVSTRYLSVEDGAFVASARQWAAFTLHLADGHSAQGDFPPREGYVRYGSLVQLVCTVTGITLPPMIIRKVAKQCALLDVDEPISQLHKCAFQFPGSPPGGGGTYLCLATEKVVQFQASPCPKEANRALLNDSSCWTIIGTESVEFSFSTSLACTLEPVTPVPLISTLELSGGGDVATLELHGENFHAGLKVWFGDVEAETMYRSPRSLVCVVPDVAAFCSDWRWLRAPITIPMSLVRADGLFYPSAFSFTYTPEYSVRPGHPGVPEPATDADALLESIHQEFTRTNFHLFIQT", "length": 517 }, "evidence": [ { "id": "A0A8V0ZSD9", "url": "https://omabrowser.org/oma/group/A0A8V0ZSD9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSD9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSD9" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSD9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSD9" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSD9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSD9" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSD9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSD9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, 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CANONICAL=A0A8V0ZSG5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZSG5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSG5/entry#A0A8V0ZSG5-1", "sequence": { "sequence": "MLCAHSPALGGAVLGTPHHRSTAPSFRGPQLSIHAQRCWISSVAPSRSCPPPRDVYPPLQLCPVPQVCGVALVAIGIYAHVALNKALVAGSSSAASSPVAIMVVGIIIFFVSFFGCCGAWKESYCMVTTFAVLLSIIFLVEIAAAIAGYVFKDKVRSVLEEGLWDTMRKYGEDVPLTEAVDKLQEDFHCCGANNYTDWATLERFRANNTVPRSCCRVNTTTCNINPTPSTIYEEGCQKGIEVWMKKNILIVAAVALGIAFFEILGIIFTCCLMKGIRSGYEVM", "length": 283, "header": "tr|A0A8V0ZSG5-1|A0A8V0ZSG5_CHICK Isoform 1 of CD63 antigen OS=Gallus gallus OX=9031 GN=CD63 PE=3 SV=1 CANONICAL=A0A8V0ZSG5-1" }, "locus": { "chromosome": "34", "start_pos": 1813510, "end_pos": 1812161, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055780.1", "url": "https://www.ensembl.org/id/ENSGALT00010055780.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033772.1", "url": "https://www.ensembl.org/id/ENSGALP00010033772.1" } ] } }, { "isoform_ac": "A0A8V0ZY02-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSG5/entry#A0A8V0ZY02-1", "sequence": { "sequence": "MAVEGGMKCVKFLVFIFNFIFWVCGVALVAIGIYAHVASAASSPVAIMVVGIIIFFVSFFGCCGAWKESYCMVTTFAVLLSIIFLVEIAAAIAGYVFKDKVRSVLEEGLWDTMRKYGEDVPLTEAVDKLQEDFHCCGANNYTDWATLERFRANNTVPRSCCRVNTTTCNINPTPSTIYEEGCQKGIEVWMKKNILIVAAVALGIAFFEILGIIFTCCLMKGIRSGYEVM", "length": 229, "header": "tr|A0A8V0ZY02-1|A0A8V0ZSG5_CHICK Computationally mapped isoform of CD63 antigen OS=Gallus gallus OX=9031 GN=CD63 PE=3 SV=1 CANONICAL=A0A8V0ZSG5-1" }, "locus": { "chromosome": "34", "start_pos": 1813510, "end_pos": 1810943, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055784.1", "url": "https://www.ensembl.org/id/ENSGALT00010055784.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033774.1", "url": "https://www.ensembl.org/id/ENSGALP00010033774.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": 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"https://www.reactome.org/PathwayBrowser/#R-GGA-1483191", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-1483213", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1483213", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "10492", "url": "https://www.rhea-db.org/rhea/10492", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "16089", "url": "https://www.rhea-db.org/rhea/16089", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZSH2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSH2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZSH2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSH2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASSRPPKYLLVFDFDETIINENSDDSIVRAAPGQALPEHIRQSFREGFYNEYMQRVLAYMGDQGVKMGDFKAVYENIPLSPGMPDLFQFLSKNHELFEIILISDANMFGIECKLRAAGFYSLFRKIFSNPSSFDKRGYFTLGPYHSHKCLDCPANMCKRKILTEYLAERAQEEVEFERVFYVGDGANDFCPSVTLTSADVAFPRKGYPMHQMTQEMEKKQPGTFQATVVPWESATEVARYLQELLKKKC", "length": 250, "header": "tr|A0A8V0ZSH2-1|A0A8V0ZSH2_CHICK Isoform 1 of Phosphoethanolamine/phosphocholine phosphatase OS=Gallus gallus OX=9031 GN=PHOSPHO1 PE=3 SV=1 CANONICAL=A0A8V0ZSH2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZSH2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSH2/entry#A0A8V0ZSH2-1", "sequence": { "sequence": "MASSRPPKYLLVFDFDETIINENSDDSIVRAAPGQALPEHIRQSFREGFYNEYMQRVLAYMGDQGVKMGDFKAVYENIPLSPGMPDLFQFLSKNHELFEIILISDANMFGIECKLRAAGFYSLFRKIFSNPSSFDKRGYFTLGPYHSHKCLDCPANMCKRKILTEYLAERAQEEVEFERVFYVGDGANDFCPSVTLTSADVAFPRKGYPMHQMTQEMEKKQPGTFQATVVPWESATEVARYLQELLKKKC", "length": 250, "header": "tr|A0A8V0ZSH2-1|A0A8V0ZSH2_CHICK Isoform 1 of Phosphoethanolamine/phosphocholine phosphatase OS=Gallus gallus OX=9031 GN=PHOSPHO1 PE=3 SV=1 CANONICAL=A0A8V0ZSH2-1" }, "locus": { "chromosome": "27", "start_pos": 3241018, "end_pos": 3240269, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010059664.1", "url": "https://www.ensembl.org/id/ENSGALT00010059664.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036444.1", "url": "https://www.ensembl.org/id/ENSGALP00010036444.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-GGA-1483191", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1483191", "resource": "Reactome", "description": "Synthesis of PC" }, { "id": "R-GGA-1483213", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1483213", "resource": "Reactome", "description": "Synthesis of PE" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "pyrophosphatase activity", "id": "GO:0016462", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016462", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSH2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSH2" } ], "pmid": "" }, { "name": "phosphocholine phosphatase activity", "id": "GO:0052731", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0052731", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSH2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSH2" } ], "pmid": "" }, { "name": "phosphoethanolamine phosphatase activity", "id": "GO:0052732", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0052732", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSH2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSH2" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSH2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSH2" } ], "pmid": "" }, { "name": "phosphatase activity", "id": "GO:0016791", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016791", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSH2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSH2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "extracellular matrix", "id": "GO:0031012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031012", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSH2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSH2" } ], "pmid": "" }, { "name": "extracellular vesicle", "id": "GO:1903561", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903561", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSH2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSH2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "bone mineralization involved in bone maturation", "id": "GO:0035630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035630", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSH2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSH2" } ], "pmid": "" }, { "name": "regulation of bone mineralization", "id": "GO:0030500", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030500", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSH2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSH2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "10492", "name": "", "equation": "phosphocholine + H2O = choline + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "O73884-1", "A0A8V0ZSH2-1" ], "evidence": [ { "id": "10492", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/10492" } ] }, { "id": "16089", "name": "", "equation": "phosphoethanolamine + H2O = ethanolamine + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "O73884-1", "Q92058-1", "F1NN44-1", "A0A8V0ZSH2-1" ], "evidence": [ { "id": "16089", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/16089" } ] }, { "id": "R-GGA-1483096", "name": "PETA is dephosphorylated to ETA by PHOSPHO1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZSH2-1" ], "evidence": [ { "id": "R-GGA-1483096", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1483096" } ] }, { "id": "R-GGA-1483159", "name": "PCho is dephosphorylated to Cho by PHOSPHO1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZSH2-1" ], "evidence": [ { "id": "R-GGA-1483159", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1483159" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0ZSH2", "gene_name": "PHOSPHO1", "activity": [ { "ec_number": "3.1.3.75", "activity": "phosphocholine + H2O = choline + phosphate.", "evidence": [ { "id": "A0A8V0ZSH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSH2" } ] }, { "ec_number": "3.1.3.75", "activity": "", "evidence": [ { "id": "A0A8V0ZSH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSH2" } ] } ] }, { "uniprot_ac": "F1NN44", "gene_name": "ALPL", "activity": [ { "ec_number": "3.1.3.1", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "F1NN44", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NN44" } ] }, { "ec_number": "3.1.3.1", "activity": "", "evidence": [ { "id": "F1NN44", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NN44" } ] } ] }, { "uniprot_ac": "O73884", "gene_name": "PHOSPHO1", "activity": [ { "ec_number": "3.1.3.75", "activity": "phosphocholine + H2O = choline + phosphate.", "evidence": [ { "id": "O73884", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O73884" } ] }, { "ec_number": "3.1.3.75", "activity": "", "evidence": [ { "id": "O73884", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O73884" } ] } ] }, { "uniprot_ac": "Q92058", "gene_name": "ALPL", "activity": [ { "ec_number": "3.1.3.1", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "Q92058", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q92058" } ] }, { "ec_number": "3.1.3.1", "activity": "", "evidence": [ { "id": "Q92058", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q92058" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [ { "evidence": [ { "id": "A0A8V0ZSH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSH2#function" }, { "id": "A0A8V0ZSH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSH2" }, { "id": "PIRSR031051-3", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR031051-3" } ], "binding_site_uniprot": 14, "amino_acid": "Asp", "chebi_lig_id": "CHEBI_18420", "ligand": "Mg(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 14, "end_pos": 14, "start_aa": "Asp", "end_aa": "Asp", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZSH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSH2#function" }, { "id": "A0A8V0ZSH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSH2" }, { "id": "PIRSR031051-3", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR031051-3" } ], "binding_site_uniprot": 16, "amino_acid": "Asp", "chebi_lig_id": "CHEBI_18420", "ligand": "Mg(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 16, "end_pos": 16, "start_aa": "Asp", "end_aa": "Asp", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZSH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSH2#function" }, { "id": "A0A8V0ZSH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSH2" }, { "id": "PIRSR031051-3", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR031051-3" } ], "binding_site_uniprot": 185, "amino_acid": "Asp", "chebi_lig_id": "CHEBI_18420", "ligand": "Mg(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 185, "end_pos": 185, "start_aa": "Asp", "end_aa": "Asp", "glycosite_overlap": "" } ], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.1.3.75", "ec_name": "phosphocholine + H2O = choline + phosphate.", "evidence": [ { "id": "3.1.3.75", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.75" }, { "id": "3.1.3.75", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.1.3.75" } ] } ], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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"o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZSH7-1", "uniprot_ac": "A0A8V0ZSH7", "uniprot_id": "A0A8V0ZSH7_CHICK", "mass": { "chemical_mass": 38014.0, "monoisotopic_mass": 38014.0 }, "refseq": { "ac": "NP_001280250", "name": "sorting nexin-20", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001280250" }, "gene_names": [ { "name": "SNX20", "type": "recommended", "evidence": [ { "id": "A0A8V0ZSH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSH7" } ] }, { "name": "SNX20", "type": "synonym", "evidence": [ { "id": "NP_001280250", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001280250" } ] } ], "protein_names": [ { "name": "Sorting nexin 20", "type": "synonym", "evidence": [ { "id": "A0A8V0ZSH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSH7/entry#names_and_taxonomy" } ] }, { "name": "sorting nexin-20", "type": "synonym", "evidence": [ { "id": "NP_001280250", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001280250" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: CR353629.1, SRR13267649.14329.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000248.1. On Dec 3, 2021 this sequence version replaced NP_001280250.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001280250", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001280250" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSH7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSH7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SNX20", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSH7", "locus": { "chromosome": "11", "start_pos": 5833103, "end_pos": 5822146, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022754", "url": "https://www.ensembl.org/id/ENSGALG00010022754" } ] } } ], "crossref": [ { "id": "A0A8V0ZSH7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZSH7", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd07300", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07300", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "415726", "url": "https://www.ncbi.nlm.nih.gov/gene/415726", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001683", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001683", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036871", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036871", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039937", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039937", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:415726", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415726", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ISCQVRK", "url": "https://omabrowser.org/oma/group/ISCQVRK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZSH7", "url": "https://www.orthodb.org/?gene=A0A8V0ZSH7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR20939", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR20939", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR20939:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR20939:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00787", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00787", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001280250", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001280250", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZSH7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSH7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZSH7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSH7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEQDPECTAERELLEAASTIATFSITAPPDEEQSQPKAEISCELSKENPGRDDLRDSKASLSPNSSMTTKELQEYWRNEKSQCRQVKLLFEIPSTRIVEHHLSKYVMYKIIILQTGSFDSNKSVIERRYSDFEKLHRNLLEDFSEEMEDVTFPKKALTGNFTDEIISERKLAFKDYLRLLYSMKFIRRSKKFIDFLTKPELQEAYGCLRGGQYNKALEILLEVIRLQERLTRGNPVAIVPTLCAIVVCHKDLGNAASAFEYGEKALSYLCMRNSHKYYIPLLEAMITLAYELGKDFLSLQEKLEEWKAKKDPVRVFSLKELAVREYVK", "length": 328, "header": "tr|A0A8V0ZSH7-1|A0A8V0ZSH7_CHICK Isoform 1 of Sorting nexin 20 OS=Gallus gallus OX=9031 GN=SNX20 PE=4 SV=1 CANONICAL=A0A8V0ZSH7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZSH7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSH7/entry#A0A8V0ZSH7-1", "sequence": { "sequence": "MEQDPECTAERELLEAASTIATFSITAPPDEEQSQPKAEISCELSKENPGRDDLRDSKASLSPNSSMTTKELQEYWRNEKSQCRQVKLLFEIPSTRIVEHHLSKYVMYKIIILQTGSFDSNKSVIERRYSDFEKLHRNLLEDFSEEMEDVTFPKKALTGNFTDEIISERKLAFKDYLRLLYSMKFIRRSKKFIDFLTKPELQEAYGCLRGGQYNKALEILLEVIRLQERLTRGNPVAIVPTLCAIVVCHKDLGNAASAFEYGEKALSYLCMRNSHKYYIPLLEAMITLAYELGKDFLSLQEKLEEWKAKKDPVRVFSLKELAVREYVK", "length": 328, "header": "tr|A0A8V0ZSH7-1|A0A8V0ZSH7_CHICK Isoform 1 of Sorting nexin 20 OS=Gallus gallus OX=9031 GN=SNX20 PE=4 SV=1 CANONICAL=A0A8V0ZSH7-1" }, "locus": { "chromosome": "11", "start_pos": 5832870, "end_pos": 5828266, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055316.1", "url": "https://www.ensembl.org/id/ENSGALT00010055316.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033482.1", "url": "https://www.ensembl.org/id/ENSGALP00010033482.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:415726", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415726", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287ANV6-1", "protein_name": "Sorting nexin 20", "gene_name": "SNX20", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MESQSMAHPGSPGWRGPTAQCMAGTKPKVPAPGPELSSVGPEEHSDAHSSLSSNSSMTTRELQEYWRTRKCRWRHVKLLFEIASARIEERRVSKFVMYQIVVIQTGSFDSNKAILERRYSDFEALQKKLLKTFPEEIEDVVFPKKHLMGNFTEEMISERKLALKEYLSLLYAIRCVRRSREFIDFLTRPELKEAFGCLRAGQYTKALDILVHVVPLQEKLTAHCPVMLVPTLCAMLVCHRDLERPAEAFAVGERALQCLQARESHRYYAPLLDAMARLAYTLGKDFVSLQERLEESQLRKPAPRGFTLKELTVQEYLC", "length": 318 }, "evidence": [ { "id": "A0A8V0ZSH7", "url": "https://omabrowser.org/oma/group/A0A8V0ZSH7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8M2BA68-1", "protein_name": "Sorting nexin-20", "gene_name": "snx20", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEEEEKPPNTTANHTVSSAPEHLSPHQETLQGNGESAEDDLCFGASCLTTAELQQHWRAVKQEFRSVKLLFDIPSARIISQTISKHVVYQVVVIRSGSYDCERVAIERRYSDFLHLHQELLSDFSEELEDVVFPKKKMTRNFSEEIIAERRVALRDYLTQLYSLRFVRKSQAFQSFFTHQELKSAYDLLRGGRFSRALEGLQKVLVLQEKLSSHDATLVIPTLCAILVCQRDLEDFEAAFETGRKALPTVRRYELRKHHGPLLEALVDLGFSLELPVAQLQDELIRVNDSPCGKETQMSLKELVVQEFV", "length": 309 }, "evidence": [ { "id": "A0A8V0ZSH7", "url": "https://omabrowser.org/oma/group/A0A8V0ZSH7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q2T9W1-1", "protein_name": "Sorting nexin-20", "gene_name": "SNX20", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MASHKHPGSPGWTGPICQDMAGTTPKASAPRPDLPRPGPEDHLEAQGSPSSNSSMTTRELQEYWRAQKCCWKHVKLLFEIASARIEERKVSKFVMYQIVVIQTGSFDSNKAVLERRYSDFETLQKKLLKTFREEIEDVVFPKKHLIGNFTEEMISERKLALKEYLSVLYAIRCVRRSREFIDFLTRPELKEAFGCLRAGQYTKALDILMRVVPLQEKLTAHCPVLLVPALCAMLVCHRDLDRPAEAFAVGERALQCLQAREGHRYYAPLLDAMARLAYLLGKDFVSLQKRLEESQLRKPALRGFTLKELTVQEYLS", "length": 316 }, "evidence": [ { "id": "A0A8V0ZSH7", "url": "https://omabrowser.org/oma/group/A0A8V0ZSH7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q5BK61-1", "protein_name": "Sorting nexin-20", "gene_name": "Snx20", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASPQHPGGPGWTGPRNQCITRTRQEVLPPGPDLPCPGPEEAQDGPTSNSNMTTRELQEHWQKEKSRWKHVRLLFEIASARIEERKVSKFVMYQVVVIQTGSFDSDKAVVERRYSDFERLQRALLKRFGPELEDVTFPRKRLTGNLSAETICERRLELREYLRLLYAVRAVRRSREFADFLTRPELCEAFGCLRAGQYARALDLLGRVVPLQEKLTAHCPSAPVPALCAMLVCLRDLERPAEAFAVGERALRRLGARESHRYYAPLLDAMVRLAYALGKDLASLQGRLDESQLRRPTHRGATLKELTVREYLS", "length": 313 }, "evidence": [ { "id": "A0A8V0ZSH7", "url": "https://omabrowser.org/oma/group/A0A8V0ZSH7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7Z614-1", "protein_name": "Sorting nexin-20", "gene_name": "SNX20", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASPEHPGSPGCMGPITQCTARTQQEAPATGPDLPHPGPDGHLDTHSGLSSNSSMTTRELQQYWQNQKCRWKHVKLLFEIASARIEERKVSKFVVYQIIVIQTGSFDNNKAVLERRYSDFAKLQKALLKTFREEIEDVEFPRKHLTGNFAEEMICERRRALQEYLGLLYAIRCVRRSREFLDFLTRPELREAFGCLRAGQYPRALELLLRVLPLQEKLTAHCPAAAVPALCAVLLCHRDLDRPAEAFAAGERALQRLQAREGHRYYAPLLDAMVRLAYALGKDFVTLQERLEESQLRRPTPRGITLKELTVREYLH", "length": 316 }, "evidence": [ { "id": "A0A8V0ZSH7", "url": "https://omabrowser.org/oma/group/A0A8V0ZSH7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9D2Y5-1", "protein_name": "Sorting nexin-20", "gene_name": "Snx20", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASPEHPGSPGWRGPINQCRTRTRQEVLPPGPDLPCPGPEEAQDGPSSNSSMTTRELQEHWQKEKSRWKHVRLLFEIASARIEERKVSKFVMYQVVVIQTGSFDSDKAVVERRYSDFERLQKALLKRFGPELEDVTFPRKRLTGNLSAETICERRRELREYLRLLYAVRAVRRSREFLDFLTRPELREAFGCLRAGQYARALELLGRALPLQEKLTAHCPSAAVPALCAALVCLRDLERPAEAFAVGERALRCLRTRENHRYYAPLLDAMVRLAYALGKDFAALQSRLDENQLRRPTHRDATLKELTVREYLS", "length": 313 }, "evidence": [ { "id": "A0A8V0ZSH7", "url": "https://omabrowser.org/oma/group/A0A8V0ZSH7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VQG1-1", "protein_name": "Sorting nexin 21, isoform A", "gene_name": "Snx21", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MPIHAVMAKRLHHQPTFDGDPPGPDELDSPAIEAAALDIPPPESDKALQKGVWERATSAEYKPTTDGSTVLRFDILLAHIMPPDGEDVKIKRFVVYELTVKQDGATEDTQPAKIERRYTDFRELYLGLKRQHPAEMANKYFPAKVLMGNFKSELIGERSAAFEAFLTYVASQAMLRDSEYFLRFLQHDELTRACQFLDERRNEMAIPILENCFRLLNKIYMNRSRPVLLILCRLVAACTSSPVPHHAAERWALLALSRFETLCDIDLLPLYIPLLHTCAHLWWQRGQDQKPITDRLTDMSKQGINTANTESLMQAIHKIDPRTETI", "length": 326 }, "evidence": [ { "id": "A0A8V0ZSH7", "url": "https://omabrowser.org/oma/group/A0A8V0ZSH7/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSH7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSH7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "early endosome membrane", "id": "GO:0031901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031901", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSH7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSH7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "phosphatidylinositol phosphate binding", "id": "GO:1901981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901981", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSH7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSH7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 121, "end_pos": 123, "annotation": "n_glycosylation_sequon" }, { "start_pos": 160, "end_pos": 162, "annotation": "n_glycosylation_sequon" }, { "start_pos": 64, "end_pos": 66, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZSH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSH7" }, { "id": "PS50195", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50195" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PX", "eco_id": "ECO_0000259", "start_pos": 86, "end_pos": 203, "start_aa": "Val", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 121, "end_pos": 123 }, { "start_pos": 160, "end_pos": 162 }, { "start_pos": 64, "end_pos": 66 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZSI2-1", "uniprot_ac": "A0A8V0ZSI2", "uniprot_id": "A0A8V0ZSI2_CHICK", "mass": { "chemical_mass": 133613.0, "monoisotopic_mass": 133613.0 }, "refseq": { "ac": "XP_004937124", "name": "zinc finger and BTB domain-containing protein 38", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004937124" }, "gene_names": [ { "name": "ZBTB38", "type": "recommended", "evidence": [ { "id": "A0A8V0ZSI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSI2" } ] }, { "name": "ZBTB38", "type": "synonym", "evidence": [ { "id": "XP_004937124", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004937124" } ] } ], "protein_names": [ { "name": "Zinc finger and BTB domain-containing protein 38", "type": "recommended", "evidence": [ { "id": "A0A8V0ZSI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSI2/entry#names_and_taxonomy" } ] }, { "name": "zinc finger and BTB domain-containing protein 38", "type": "synonym", "evidence": [ { "id": "XP_004937124", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004937124" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052540.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004937124.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004937124", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004937124" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSI2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSI2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ZBTB38", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSI2", "locus": { "chromosome": "9", "start_pos": 9879867, "end_pos": 9786776, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010023274", "url": "https://www.ensembl.org/id/ENSGALG00010023274" } ] } } ], "crossref": [ { "id": "cd18223", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18223", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "424783", "url": "https://www.ncbi.nlm.nih.gov/gene/424783", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:424783", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424783", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SECVEMN", "url": "https://omabrowser.org/oma/group/SECVEMN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZSI2", "url": "https://www.orthodb.org/?gene=A0A8V0ZSI2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24394", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24394", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24394:SF58", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24394:SF58", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00651", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00651", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12874", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12874", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004937124", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004937124", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZSI2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSI2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZSI2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSI2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTVMSHSKDLKDDFHSDTVLSILNEQRIRGILCDVTIIVEDTKFKAHSNVLAASSLYFKNIFWSRTICISGHVLELDDLKAEVFTEILNYIYSSTVVVKRQETVTDLAAAGKKLGISFLEDLTDANFSSSPCPYAYCVSEKGTVKEEKHEKRHEDSAVTNGPRITNAFSIFETENSLFSPLDLRANFKKVSETVQTPSVSLDRNNTCKDAEPASTLAEHSYAVSSGGDTFQGTPHFEQESSSSYNAGEDHYENLRATPLIQPVKQACSTTPKAAFKSQGTGLAVAKVPASTVANAEAQPETVNDQRIISIPKPQNKAGDFHLSREEENTSANISGSVTTAVTPAYSCNCCAKSFSDRALLSTHLQLHSEHQETFICKYCSKQFANLNILESHEQVCMRSSSLSVHSGNEQNFSDNYTATDGRNESSYANTEPLLSENSITDYSNANCALPETDHLVKVVDGQILYTCIVCKRSYVTLSSLRRHANVHSWRRTYPCHYCNKVFALAEYRTRHEIWHTGERRYQCIFCLETFMTYYILKNHQKSFHAIDHRLSVSKKTANGGLKPSVYPYKLYRLLPMKCRRLPYKSYRNSTYENVQTSSQVNETASSNCFIQSSISAELPPLNFQTNILTNNRTLVLDTSSCNDTASSTNPQNSSSWGVGILNSDLQRDFFTADKRVPTATKDSGSHEYDSSVVSLTNVNENSTSVISYSSSAPSVIMHSSRVSSVIMHSKTITSVENSKTESSNSVPSQPVSDDCNYGSDNYGKCITKSKPIKEKKKALLGSRAEAAEDTQHVQGSGGSSSKTTNTAEESSKTETYIAKPALPGTSTDSNVAPLCQITVKIGNEAIVKRHILGSKLFCKRGRKSKHESKQDNLNEESEAEIKEKSPSRLYSSECLELTEMCDDVSDQDSSDKPWRPYYNYKPKKKSKQLRKMKKTKWRKKHGNRNTVTESHSTCSREYALRSAPEDKAVSQEENTEMPSLHCELCEGDQNSTTETQEHVHWHLSSSKPYICELCQKQFQSPSTLKMHMRCHTGEKPFTCKTCGKCFSVPGNLQKHERIHLGVKDFVCQYCNKAFTLNETLKIHERIHTGEKRYHCQFCLQSFLYLSTKRNHEQRHIREHNGKGYACFQCPKICKTAAALGMHQKKHLFKSTGPQDRKEQFCNESAQLLENQHFLGSEGSEGKSIQSVTPEVIL", "length": 1193, "header": "tr|A0A8V0ZSI2-1|A0A8V0ZSI2_CHICK Isoform 1 of Zinc finger and BTB domain-containing protein 38 OS=Gallus gallus OX=9031 GN=ZBTB38 PE=4 SV=1 CANONICAL=A0A8V0ZSI2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZSI2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSI2/entry#A0A8V0ZSI2-1", "sequence": { "sequence": "MTVMSHSKDLKDDFHSDTVLSILNEQRIRGILCDVTIIVEDTKFKAHSNVLAASSLYFKNIFWSRTICISGHVLELDDLKAEVFTEILNYIYSSTVVVKRQETVTDLAAAGKKLGISFLEDLTDANFSSSPCPYAYCVSEKGTVKEEKHEKRHEDSAVTNGPRITNAFSIFETENSLFSPLDLRANFKKVSETVQTPSVSLDRNNTCKDAEPASTLAEHSYAVSSGGDTFQGTPHFEQESSSSYNAGEDHYENLRATPLIQPVKQACSTTPKAAFKSQGTGLAVAKVPASTVANAEAQPETVNDQRIISIPKPQNKAGDFHLSREEENTSANISGSVTTAVTPAYSCNCCAKSFSDRALLSTHLQLHSEHQETFICKYCSKQFANLNILESHEQVCMRSSSLSVHSGNEQNFSDNYTATDGRNESSYANTEPLLSENSITDYSNANCALPETDHLVKVVDGQILYTCIVCKRSYVTLSSLRRHANVHSWRRTYPCHYCNKVFALAEYRTRHEIWHTGERRYQCIFCLETFMTYYILKNHQKSFHAIDHRLSVSKKTANGGLKPSVYPYKLYRLLPMKCRRLPYKSYRNSTYENVQTSSQVNETASSNCFIQSSISAELPPLNFQTNILTNNRTLVLDTSSCNDTASSTNPQNSSSWGVGILNSDLQRDFFTADKRVPTATKDSGSHEYDSSVVSLTNVNENSTSVISYSSSAPSVIMHSSRVSSVIMHSKTITSVENSKTESSNSVPSQPVSDDCNYGSDNYGKCITKSKPIKEKKKALLGSRAEAAEDTQHVQGSGGSSSKTTNTAEESSKTETYIAKPALPGTSTDSNVAPLCQITVKIGNEAIVKRHILGSKLFCKRGRKSKHESKQDNLNEESEAEIKEKSPSRLYSSECLELTEMCDDVSDQDSSDKPWRPYYNYKPKKKSKQLRKMKKTKWRKKHGNRNTVTESHSTCSREYALRSAPEDKAVSQEENTEMPSLHCELCEGDQNSTTETQEHVHWHLSSSKPYICELCQKQFQSPSTLKMHMRCHTGEKPFTCKTCGKCFSVPGNLQKHERIHLGVKDFVCQYCNKAFTLNETLKIHERIHTGEKRYHCQFCLQSFLYLSTKRNHEQRHIREHNGKGYACFQCPKICKTAAALGMHQKKHLFKSTGPQDRKEQFCNESAQLLENQHFLGSEGSEGKSIQSVTPEVIL", "length": 1193, "header": "tr|A0A8V0ZSI2-1|A0A8V0ZSI2_CHICK Isoform 1 of Zinc finger and BTB domain-containing protein 38 OS=Gallus gallus OX=9031 GN=ZBTB38 PE=4 SV=1 CANONICAL=A0A8V0ZSI2-1" }, "locus": { "chromosome": "9", "start_pos": 9875140, "end_pos": 9871562, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056760.1", "url": "https://www.ensembl.org/id/ENSGALT00010056760.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034502.1", "url": "https://www.ensembl.org/id/ENSGALP00010034502.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 342, "start_aa": "Thr", "end_pos": 342, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr342", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:424783", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424783", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2LA71-1", "protein_name": "Zinc finger and BTB domain-containing protein 38", "gene_name": "Zbtb38", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MTVMSLSRDLKDDFHSDTVLSILNEQRIRGILCDVTIIVEDTKFKAHSNVLAASSLYFKNIFWSHTICISSHVLELDDLKAEVFTEILNYIYSSTVVVKRQETVTDLAAAGKKLGISFLEDLSDRNFSNSPGPYVVCITEKGVVKEEKNEKRHEEPAITNGPRITNAFSIIETENSNNMFSPLDLRASFKKVSDSMRTTSLCQERTNVCHEAEPVRTLAEHSYAVSSITEAYRNQPVREHDSSLSGKTGKENGEALVTKVKPCRKPKTQSQESDSTPEKTPLLPVTSPEVNQEKSPQPAPILSQSEPPSKEGDVHFTREEENQPSDDIPGPTAAEVPPLVYNCSCCSKSFDSSILLSAHMQLHKPTQEPFVCKYCNKQFTTLNRLDRHEHICMRSSHVPIPGGNQQFLENYPTIGQNGSSFPNPESLVPENNIGELSSAGSALPDADHIVKFVNGQMLYSCIVCKRSYVTLSSLRRHANVHSWRRTYPCHYCNKVFALAEYRTRHEIWHTGERRYQCIFCLETFMTYYILKNHQKSFHAIDHRLSISKKTANGGLKPNVYPYKLYRLLPMRCKRAPYKSFRNSSYESSRENSQRSESAPDTFVVPNSQSSEMPTLNFQDGRNTLTSIPAIPVETPAHQGTLTSAKVKNAEGTKWKKEALKTGLVNNFDSTEASVSSTVRANLQAEPTHGATMGGGSEQSASVISYSGSVPSVIVHSSQFSSVIKHSNTFAALTSSNDKAPSQPVISPSLKEDSKPEADKASKLASRPKSIKEKKKAIPCNRGEITEEAKHVADPGGSLGKTTNAVEETSKIETYIAKPALPGTSTNSNVAPLCQITVKIGNEAIVKRHILGSKLFYKRGRKPKYQIQEESLPQESDPETHGDSPLGLCQAECVEMSEAFDDASDQDSTDKPWRPYYNYKPKKKSKQLRKMRKVKWRKEHGVRSPSGRCRYPAELDRAEVKPPPDKAFEEEENKEMPKLQCELCDGDKAGGMEAEGKPHQHLTLKPYICELCAKQFQSPSTLKMHMRCHTGEKPYQCKTCGRCFSVQGNLQKHERIHLGVKEFICQYCNKAFTLNETLKIHERIHTGEKRYHCQFCFQGFLYLSTKRNHERRHVREHDGKGFACFQCPKICKTAAALRMHQKKHLFKTLTKQEKTDDMCHENSDLLESQLCTDSEDSDQKDDIQTFAKSVQ", "length": 1190 }, "evidence": [ { "id": "A0A8V0ZSI2", "url": "https://omabrowser.org/oma/group/A0A8V0ZSI2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "I3LE33-1", "protein_name": "Zinc finger and BTB domain-containing protein 38", "gene_name": "ZBTB38", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTVMSLSRDLKDDFHSDTVLSILNEQRIRGILCDVTIIVEDTKFKAHSNVLAASSLYFKNIFWSHTICISSHVLELDDLKAEVFTEILNYIYSSTVVVKRQETVTDLAAAGKKLGISFLEDLTDRNFSNSPGPYVFCITEKGVVKEEKNEKRHEEPAITNGPRITNAFSIIETENSNNMFSPLDLRASFKKVSDSMRTTSLCLERTDVCHEVEPVRTLAEHSYAVSSMAEAYRSQPVREQDSGSPEKTGTENCEAVAAKPKTSRKPKTPSVSQDSDSTPENISPPPASNLEVNQEESPQPVAILSRSKSPNNNEGEVRFPREDENKSSEVPGPPATEVPPLVYNCSCCSKSFDSSTLLSAHMQLHKPTQEPLVCKYCNKQFSTLNRLDRHEQICMRSSHMPVPGGNQRFLENYPTIGQNGSSFTGPESLLSENRMGEFSSPGSTLPETDHMVKFVNGQMLYSCVVCKRSYVTLSSLRRHANVHSWRRTYPCHYCNKVFALAEYRTRHEIWHTGERRYQCIFCLETFMTYYILKNHQKSFHAIDHRLSISKKTANGGLKPSVYPYKLYRLLPMKCKRAPYKSYRHSSYENTRENSQMNESAPGPYVIQNPHGSELPTLNFQDSVSTLTNSPAIPLETPARQDLPTPASVQNTEGTKWGERGELKVDLDSRFYSAEMSVPSTENTSSSDHRAGEAPTLSASNGSENSASVISYSGSAPSVIVHSSQFSSVIMHSNAITPEMGHKPRAPLDLAVSQTPKEDGRPEPDKMGRGVNRPKSGKEKKKTIPCNRGEIPEEPRYVADPGGSLSKTTNIMKETSKIETYIAKPALPGTSTNSNVAPLCQITVKIGNEAIVKRHILGSKLFYKRGRRSKYQVQEETLPQESDQETNRASPLGLCQAECMEMSEMFDDASDQDSTDKPWRPYYNYKPKKKSRQLRKMRKANWRKEHENRSPSGKCKYPAELDCAVGKAPQEKPLEEEENKEMPKLQCELCDGDKASGAGNPGRPHRHLTARPYACELCAKPFQSPSTLKMHMRCHTGEKPYQCKTCGRCFSVQGNLQKHMRIHLGVKEFVCQYCNKAFTLNETLKIHERIHTGEKRYHCQFCFQSFLYLSTKRNHEQRHVQEHNGKGYACFQCPKICKTAAALGMHQKKHLFKSPSQREKTEGDVGQENSHPLENPHFLDSEDSDQKDNVQTLADNVL", "length": 1197 }, "evidence": [ { "id": "A0A8V0ZSI2", "url": "https://omabrowser.org/oma/group/A0A8V0ZSI2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q5EXX3-1", "protein_name": "Zinc finger and BTB domain-containing protein 38", "gene_name": "Zbtb38", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTVMSLSRDLKDDFHSDTVLSILNEQRIRGILCDVTIIVEDTKFKAHSNVLAASSLYFKNIFWSHTICISSHVLELDDLKAEVFTEILNYIYSSTVVVRRQETVTDLAAAGKRLGISFLEDLSDRNFSNSPGPYVVCITEKGVVKEEKNEKRHEEPAVTNGPRITNAFSIIETENSNSMFSPLDLRASFKKVSDAMRTTSLCQERASVCPEAEPVRTLAEHSYAVSSITEAYRSQPLREHDSSSSSGKTGKENGEALTTKAKPCRKPKTQTQDSDSTTENMPLPLVTCPEVNQERSPQPAPILSHSEPPSSEGDVHFPREDENQPSETPGPPAAEVPPLVYNCSCCSKSFDSSTLLGAHMQLHKPTQDPFVCKYCNKQFTTLNRLDRHEQICMRSSHMPMPGGNQPFLENYPTIGQDGGSFTSPDSLVPESRIGELSSAGSALSDADHMVKFVNGQMLYSCVVCKRSYVTLSSLRRHANVHSWRRTYPCHYCNKVFALAEYRTRHEIWHTGERRYQCIFCLETFMTYYILKNHQKSFHAIDHRLSISKKTANGGLKPTVYPYKLYRLLPMRCKRAPYKSYRNSSYESAQGNRQRNESPPDTFVIPNLPSSEMPTLNFQDGRNSLTSSPAIPVETPSWQGTPTSAKVKNAEGLKWRKQALKTDLVDSAEVSISSIGNSVSTTLQAEPVCVSSGEHSASVISYSGLVPSVIVHSSQFSSVIKHSNAIACLANSNHQSPSQPVASPSLIKDSKPEADKASKLASRPKNSKEKKKTVPCNRGEITEEAKYVADLGGSSGKTTNVVEETSKIETYIAKPALPGTSTNSNVAPLCQITVKIGNEAIVKRHILGSKLFYKRGRKPKYQMQEETLPRESDPETRGDSPLGLCQADCVEMSEAFDEVSDQDSTDKPWRPYYNYKPKKKSKQLRKIRKVKWRKERGSRSPVGRRRYPAELDRAEMGRRRYPAELDRCAEVKLPPDKASEEEENKEMPKLQCELCDGDKAAGAGAEGKPHQHLTLKPYICELCAKQFQSSSTLKMHMRCHTGEKPYQCKTCGRRFSVQGNLQKHERIHLGVKEFICQYCNKAFTLNETLKIHERIHTGEKRYHCQFCFQGFLYLSTKRNHERRHVREHDGKGFACFQCPKICKTAAALRMHQKKHLFKTLTKQEETDDLCHENSDLLESQPCTDSEDSDQKDDIKKPLLKMSFE", "length": 1203 }, "evidence": [ { "id": "A0A8V0ZSI2", "url": "https://omabrowser.org/oma/group/A0A8V0ZSI2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8NAP3-1", "protein_name": "Zinc finger and BTB domain-containing protein 38", "gene_name": "ZBTB38", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTVMSLSRDLKDDFHSDTVLSILNEQRIRGILCDVTIIVEDTKFKAHSNVLAASSLYFKNIFWSHTICISSHVLELDDLKAEVFTEILNYIYSSTVVVKRQETVTDLAAAGKKLGISFLEDLTDRNFSNSPGPYVFCITEKGVVKEEKNEKRHEEPAITNGPRITNAFSIIETENSNNMFSPLDLRASFKKVSDSMRTASLCLERTDVCHEAEPVRTLAEHSYAVSSVAEAYRSQPVREHDGSSPGNTGKENCEALAAKPKTCRKPKTFSIPQDSDSATENIPPPPVSNLEVNQERSPQPAAVLTRSKSPNNEGDVHFSREDENQSSDVPGPPAAEVPPLVYNCSCCSKAFDSSTLLSAHMQLHKPTQEPLVCKYCNKQFTTLNRLDRHEQICMRSSHMPIPGGNQRFLENYPTIGQNGGSFTGPEPLLSENRIGEFSSTGSTLPDTDHMVKFVNGQMLYSCVVCKRSYVTLSSLRRHANVHSWRRTYPCHYCNKVFALAEYRTRHEIWHTGERRYQCIFCLETFMTYYILKNHQKSFHAIDHRLSISKKTANGGLKPSVYPYKLYRLLPMKCKRAPYKSYRNSSYENARENSQMNESAPGTYVVQNPHSSELPTLNFQDTVNTLTNSPAIPLETSACQDIPTSANVQNAEGTKWGEEALKMDLDNNFYSTEVSVSSTENAVSSDLRAGDVPVLSLSNSSENAASVISYSGSAPSVIVHSSQFSSVIMHSNAIAAMTSSNHRAFSDPAVSQSLKDDSKPEPDKVGRFASRPKSIKEKKKTTSHTRGEIPEESNYVADPGGSLSKTTNIAEETSKIETYIAKPALPGTSTNSNVAPLCQITVKIGNEAIVKRHILGSKLFYKRGRRPKYQMQEEPLPQGNDPEPSGDSPLGLCQSECMEMSEVFDDASDQDSTDKPWRPYYNYKPKKKSRQLKKMRKVNWRKEHGNRSPSHKCKYPAELDCAVGKAPQDKPFEEEETKEMPKLQCELCDGDKAVGAGNQGRPHRHLTSRPYACELCAKQFQSPSTLKMHMRCHTGEKPYQCKTCGRCFSVQGNLQKHERIHLGLKEFVCQYCNKAFTLNETLKIHERIHTGEKRYHCQFCFQRFLYLSTKRNHEQRHIREHNGKGYACFQCPKICKTAAALGMHQKKHLFKSPSQQEKIGDVCHENSNPLENQHFIGSEDNDQKDNIQTGVENVVL", "length": 1195 }, "evidence": [ { "id": "A0A8V0ZSI2", "url": "https://omabrowser.org/oma/group/A0A8V0ZSI2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSI2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSI2" } ], "pmid": "" }, { "name": "chromosome", "id": "GO:0005694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005694", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSI2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSI2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSI2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSI2" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSI2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSI2" } ], "pmid": "" }, { "name": "negative regulation of DNA-templated transcription", "id": "GO:0045892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045892", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSI2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSI2" } ], "pmid": "" }, { "name": "DNA damage response", "id": "GO:0006974", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006974", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSI2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSI2" } ], "pmid": "" }, { "name": "regulation of DNA replication", "id": "GO:0006275", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006275", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSI2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSI2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSI2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSI2" } ], "pmid": "" }, { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSI2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSI2" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSI2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSI2" } ], "pmid": "" }, { "name": "DNA-binding transcription 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"MMERKCLVAQVANVALAMEIKATAAWTGVIWFSPKPEVLHRAQTACRIWQPRGSHEALRCKATQLGSGADGSLTRGMPCSGTPARCHHAYRRFTSSGVGLEAISSLQRIFNSFMYTEKISNGESEVQQLAKKIREKFNRYLDVVNRNKQVVEASYTAHLTSPLTAIQDCCTIPPSMMEFDGNFNTNVSRTISCDRLSTTVNSRAFNPGRDLNSVLADNLKSNPGIKWQYFSSEEGIFTVFPAHKFRCKGSYEHRSRPVYVSTVRPQSKHIVVIVDHGASVTETQLQIAKDAAQVILSSIDEHDKISVLTVADTVRTCSLDQCYKTFLSPATSETKRKMSTFVSSIKSSDSPTQHAIGFQKAFQLIRNTNNGTKLQGNTDMVIISLSAGITSKDSSEDDKKATLRVINEENSFLNNSVMILTYALMNEGVTGLKELAFLRDLAEQNSVKYGVPDRTTLPVIKGSMMVLNQLSNLETTVGRFYTNLPNRMIDEAVFSLPFSDEMGDGLIMTVSKPCYFGNLLLGIVGVDVNLAYILEDVTYYQDSLGSYTFLIDNKGYTLMHPSLTRPYLLSEPPLHTDIIHYENIPKFELVRQNILSIPLGSQIITVPVNSSLSWHVNKLREVGKEAYNVSYAWKMVQDTSFILCVVVIQPEIPVKQLKNLNTVPSSKLLYHRLDLLGQPNACLHFKQLATLESPTVMLSAGSFSSPYEHLSQPETKRMVEHYTAYLSDNTRLIANPGLKFSVRNEVMATSHVTDEWMTQMEMSSYEQLNSYIVRRYIATPNGVLRIYPGSLMDKAFDPTRRQWYLHAVANPGLITFTGPYLDVGGAGYVVTISHTIHSSSAQMSSGHSVAVMGIDFTLRYFYKVLMDLLPVCNQDGGNKIRCFIMEDRGYLVAHPTLIDPKGHAPVEQQHITHKEPLVANDILNHPNFVKKNLCNSFSDRTVQRFYKFNTSLVGDLTNLVHGSHCSKYRLTRIPGTNAFVGIVNETCDSLAFCACSMVDRLCLNCHRMEQNECECPCECPLEVNECTGNLTNAESRNPSCEVHQEPMTFTAIDPSLQDALPQCINTQCNQRTESGDCFGVLDCEWCMVDSDGKTHLDKSYCAPQKECFGGIVGAKSPYVDDLGAIGDEVITLNMIKSAPVGPVAGGIMGCIMVLVLAVYAYRHQIHRRSHQHMSPLAAQEMSVRMSNLENDRDERDDDSHEDRGIISNTRFIAAVIERHAHSPERRRRYWGRSGTESDHGYSTMSPQEDSENPPCNNDPLSAGVDVGNHDEDLDLDTPPQTAALLSHKFHHYRLHHPTLHHSHHLQAAVTVHTVDAEC", "length": 1318, "header": "tr|A0A8V0ZSJ7-1|A0A8V0ZSJ7_CHICK Isoform 1 of VWFA and cache domain-containing protein 1 OS=Gallus gallus OX=9031 GN=CACHD1 PE=3 SV=1 CANONICAL=A0A8V0ZSJ7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZSI6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSJ7/entry#A0A8V0ZSI6-1", "sequence": { "sequence": "MRKLATEELGVVTMQRIFNSFMYTEKISNGESEVQQLAKKIREKFNRYLDVVNRNKQVVEASYTAHLTSPLTAIQDCCTIPPSMMEFDGNFNTNVSRTISCDRLSTTVNSRAFNPGRDLNSVLADNLKSNPGIKWQYFSSEEGIFTVFPAHKFRCKGSYEHRSRPVYVSTVRPQSKHIVVIVDHGASVTETQLQIAKDAAQVILSSIDEHDKISVLTVADTVRTCSLDQCYKTFLSPATSETKRKMSTFVSSIKSSDSPTQHAIGFQKAFQLIRNTNNGTKLQGNTDMVIISLSAGITSKDSSEDDKKATLRVINEENSFLNNSVMILTYALMNEGVTGLKELAFLRDLAEQNSVKYGVPDRTTLPVIKGSMMVLNQLSNLETTVGRFYTNLPNRMIDEAVFSLPFSDEMGDGLIMTVSKPCYFGNLLLGIVGVDVNLAYILEDVTYYQDSLGSYTFLIDNKGYTLMHPSLTRPYLLSEPPLHTDIIHYENIPKFELVRQNILSIPLGSQIITVPVNSSLSWHVNKLREVGKEAYNVSYAWKMVQDTSFILCVVVIQPEIPVKQLKNLNTVPSSKLLYHRLDLLGQPNACLHFKQLATLESPTVMLSAGSFSSPYEHLSQPETKRMVEHYTAYLSDNTRLIANPGLKFSVRNEVMATSHVTDEWMTQMEMSSYEQLNSYIVRRYIATPNGVLRIYPGSLMDKAFDPTRRQWYLHAVANPGLITFTGPYLDVGGAGYVVTISHTIHSSSAQMSSGHSVAVMGIDFTLRYFYKVLMDLLPVCNQDGGNKIRCFIMEDRGYLVAHPTLIDPKGHAPVEQQHITHKEPLVANDILNHPNFVKKNLCNSFSDRTVQRFYKFNTSLVGDLTNLVHGSHCSKYRLTRIPGTNAFVGIVNETCDSLAFCACSMVDRLCLNCHRMEQNECECPCECPLEVNECTGNLTNAESRNPSCEVHQEPMTFTAIDPSLQDALPQCINTQCNQRTESGDCFGVLDCEWCMVDSDGKTHLDKSYCAPQKECFGGIVGAKSPYVDDLGAIGDEVITLNMIKSAPVGPVAGGIMGCIMVLVLAVYAYRHQIHRRSHQHMSPLAAQEMSVRMSNLENDRDERDDDSHEDRGISYSTMSPQEDSENPPCNNDPLSAGVDVGNHDEDLDLDTPPQTAALLSHKFHHYRLHHPTLHHSHHLQAAVTVHTVDAEC", "length": 1192, "header": "tr|A0A8V0ZSI6-1|A0A8V0ZSJ7_CHICK Computationally mapped isoform of VWFA and cache domain-containing protein 1 OS=Gallus gallus OX=9031 GN=CACHD1 PE=3 SV=1 CANONICAL=A0A8V0ZSJ7-1" }, "locus": { "chromosome": "8", "start_pos": 27844442, "end_pos": 27762740, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010059671.1", "url": "https://www.ensembl.org/id/ENSGALT00010059671.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036449.1", "url": "https://www.ensembl.org/id/ENSGALP00010036449.1" } ] } }, { "isoform_ac": "A0A8V0ZSJ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSJ7/entry#A0A8V0ZSJ7-1", "sequence": { "sequence": "MMERKCLVAQVANVALAMEIKATAAWTGVIWFSPKPEVLHRAQTACRIWQPRGSHEALRCKATQLGSGADGSLTRGMPCSGTPARCHHAYRRFTSSGVGLEAISSLQRIFNSFMYTEKISNGESEVQQLAKKIREKFNRYLDVVNRNKQVVEASYTAHLTSPLTAIQDCCTIPPSMMEFDGNFNTNVSRTISCDRLSTTVNSRAFNPGRDLNSVLADNLKSNPGIKWQYFSSEEGIFTVFPAHKFRCKGSYEHRSRPVYVSTVRPQSKHIVVIVDHGASVTETQLQIAKDAAQVILSSIDEHDKISVLTVADTVRTCSLDQCYKTFLSPATSETKRKMSTFVSSIKSSDSPTQHAIGFQKAFQLIRNTNNGTKLQGNTDMVIISLSAGITSKDSSEDDKKATLRVINEENSFLNNSVMILTYALMNEGVTGLKELAFLRDLAEQNSVKYGVPDRTTLPVIKGSMMVLNQLSNLETTVGRFYTNLPNRMIDEAVFSLPFSDEMGDGLIMTVSKPCYFGNLLLGIVGVDVNLAYILEDVTYYQDSLGSYTFLIDNKGYTLMHPSLTRPYLLSEPPLHTDIIHYENIPKFELVRQNILSIPLGSQIITVPVNSSLSWHVNKLREVGKEAYNVSYAWKMVQDTSFILCVVVIQPEIPVKQLKNLNTVPSSKLLYHRLDLLGQPNACLHFKQLATLESPTVMLSAGSFSSPYEHLSQPETKRMVEHYTAYLSDNTRLIANPGLKFSVRNEVMATSHVTDEWMTQMEMSSYEQLNSYIVRRYIATPNGVLRIYPGSLMDKAFDPTRRQWYLHAVANPGLITFTGPYLDVGGAGYVVTISHTIHSSSAQMSSGHSVAVMGIDFTLRYFYKVLMDLLPVCNQDGGNKIRCFIMEDRGYLVAHPTLIDPKGHAPVEQQHITHKEPLVANDILNHPNFVKKNLCNSFSDRTVQRFYKFNTSLVGDLTNLVHGSHCSKYRLTRIPGTNAFVGIVNETCDSLAFCACSMVDRLCLNCHRMEQNECECPCECPLEVNECTGNLTNAESRNPSCEVHQEPMTFTAIDPSLQDALPQCINTQCNQRTESGDCFGVLDCEWCMVDSDGKTHLDKSYCAPQKECFGGIVGAKSPYVDDLGAIGDEVITLNMIKSAPVGPVAGGIMGCIMVLVLAVYAYRHQIHRRSHQHMSPLAAQEMSVRMSNLENDRDERDDDSHEDRGIISNTRFIAAVIERHAHSPERRRRYWGRSGTESDHGYSTMSPQEDSENPPCNNDPLSAGVDVGNHDEDLDLDTPPQTAALLSHKFHHYRLHHPTLHHSHHLQAAVTVHTVDAEC", "length": 1318, "header": "tr|A0A8V0ZSJ7-1|A0A8V0ZSJ7_CHICK Isoform 1 of VWFA and cache domain-containing protein 1 OS=Gallus gallus OX=9031 GN=CACHD1 PE=3 SV=1 CANONICAL=A0A8V0ZSJ7-1" }, "locus": { "chromosome": "8", "start_pos": 27844442, "end_pos": 27760905, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010059683.1", "url": "https://www.ensembl.org/id/ENSGALT00010059683.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036459.1", "url": "https://www.ensembl.org/id/ENSGALP00010036459.1" } ] } }, { "isoform_ac": "A0A8V0ZXM4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSJ7/entry#A0A8V0ZXM4-1", "sequence": { "sequence": "MESILSAKSQLICRLRIFNSFMYTEKISNGESEVQQLAKKIREKFNRYLDVVNRNKQVVEASYTAHLTSPLTAIQDCCTIPPSMMEFDGNFNTNVSRTISCDRLSTTVNSRAFNPGRDLNSVLADNLKSNPGIKWQYFSSEEGIFTVFPAHKFRCKGSYEHRSRPVYVSTVRPQSKHIVVIVDHGASVTETQLQIAKDAAQVILSSIDEHDKISVLTVADTVRTCSLDQCYKTFLSPATSETKRKMSTFVSSIKSSDSPTQHAIGFQKAFQLIRNTNNGTKLQGNTDMVIISLSAGITSKDSSEDDKKATLRVINEENSFLNNSVMILTYALMNEGVTGLKELAFLRDLAEQNSVKYGVPDRTTLPVIKGSMMVLNQLSNLETTVGRFYTNLPNRMIDEAVFSLPFSDEMGDGLIMTVSKPCYFGNLLLGIVGVDVNLAYILEDVTYYQDSLGSYTFLIDNKGYTLMHPSLTRPYLLSEPPLHTDIIHYENIPKFELVRQNILSIPLGSQIITVPVNSSLSWHVNKLREVGKEAYNVSYAWKMVQDTSFILCVVVIQPEIPVKQLKNLNTVPSSKLLYHRLDLLGQPNACLHFKQLATLESPTVMLSAGSFSSPYEHLSQPETKRMVEHYTAYLSDNTRLIANPGLKFSVRNEVMATSHVTDEWMTQMEMSSYEQLNSYIVRRYIATPNGVLRIYPGSLMDKAFDPTRRQWYLHAVANPGLITFTGPYLDVGGAGYVVTISHTIHSSSAQMSSGHSVAVMGIDFTLRYFYKVLMDLLPVCNQDGGNKIRCFIMEDRGYLVAHPTLIDPKGHAPVEQQHITHKEPLVANDILNHPNFVKKNLCNSFSDRTVQRFYKFNTSLVGDLTNLVHGSHCSKYRLTRIPGTNAFVGIVNETCDSLAFCACSMVDRLCLNCHRMEQNECECPCECPLEVNECTGNLTNAESRNPSCEVHQEPMTFTAIDPSLQDALPQCINTQCNQRTESGDCFGVLDCEWCMVDSDGKTHLDKSYCAPQKECFGGIVGAKSPYVDDLGAIGDEVITLNMIKSAPVGPVAGGIMGCIMVLVLAVYAYRHQIHRRSHQHMSPLAAQEMSVRMSNLENDRDERDDDSHEDRGIISNTRFIAAVIERHAHSPERRRRYWGRSGTESDHGYSTMSPQEDSENPPCNNDPLSAGVDVGNHDEDLDLDTPPQTAALLSHKFHHYRLHHPTLHHSHHLQAAVTVHTVDAEC", "length": 1226, "header": "tr|A0A8V0ZXM4-1|A0A8V0ZSJ7_CHICK Computationally mapped isoform of VWFA and cache domain-containing protein 1 OS=Gallus gallus OX=9031 GN=CACHD1 PE=3 SV=1 CANONICAL=A0A8V0ZSJ7-1" }, "locus": { "chromosome": "8", "start_pos": 27844442, "end_pos": 27791492, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010059654.1", "url": "https://www.ensembl.org/id/ENSGALT00010059654.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036436.1", "url": "https://www.ensembl.org/id/ENSGALP00010036436.1" } ] } }, { "isoform_ac": "A0A8V0ZZU9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSJ7/entry#A0A8V0ZZU9-1", "sequence": { "sequence": "MKSKGGVLFFVRIFNSFMYTEKISNGESEVQQLAKKIREKFNRYLDVVNRNKQVVEASYTAHLTSPLTAIQDCCTIPPSMMEFDGNFNTNVSRTISCDRLSTTVNSRAFNPGRDLNSVLADNLKSNPGIKWQYFSSEEGIFTVFPAHKFRCKGSYEHRSRPVYVSTVRPQSKHIVVIVDHGASVTETQLQIAKDAAQVILSSIDEHDKISVLTVADTVRTCSLDQCYKTFLSPATSETKRKMSTFVSSIKSSDSPTQHAIGFQKAFQLIRNTNNGTKLQGNTDMVIISLSAGITSKDSSEDDKKATLRVINEENSFLNNSVMILTYALMNEGVTGLKELAFLRDLAEQNSVKYGVPDRTTLPVIKGSMMVLNQLSNLETTVGRFYTNLPNRMIDEAVFSLPFSDEMGDGLIMTVSKPCYFGNLLLGIVGVDVNLAYILEDVTYYQDSLGSYTFLIDNKGYTLMHPSLTRPYLLSEPPLHTDIIHYENIPKFELVRQNILSIPLGSQIITVPVNSSLSWHVNKLREVGKEAYNVSYAWKMVQDTSFILCVVVIQPEIPVKQLKNLNTVPSSKLLYHRLDLLGQPNACLHFKQLATLESPTVMLSAGSFSSPYEHLSQPETKRMVEHYTAYLSDNTRLIANPGLKFSVRNEVMATSHVTDEWMTQMEMSSYEQLNSYIVRRYIATPNGVLRIYPGSLMDKAFDPTRRQWYLHAVANPGLITFTGPYLDVGGAGYVVTISHTIHSSSAQMSSGHSVAVMGIDFTLRYFYKVLMDLLPVCNQDGGNKIRCFIMEDRGYLVAHPTLIDPKGHAPVEQQHITHKEPLVANDILNHPNFVKKNLCNSFSDRTVQRFYKFNTSLVGDLTNLVHGSHCSKYRLTRIPGTNAFVGIVNETCDSLAFCACSMVDRLCLNCHRMEQNECECPCECPLEVNECTGNLTNAESRNPSCEVHQEPMTFTAIDPSLQDALPQCINTQCNQRTESGDCFGVLDCEWCMVDSDGKTHLDKSYCAPQKECFGGIVGAKSPYVDDLGAIGDEVITLNMIKSAPVGPVAGGIMGCIMVLVLAVYAYRHQIHRRSHQHMSPLAAQEMSVRMSNLENDRDERDDDSHEDRGIISNTRFIAAVIERHAHSPERRRRYWGRSGTESDHGYSTMSPQEDSENPPCNNDPLSAGVDVGNHDEDLDLDTPPQTAALLSHKFHHYRLHHPTLHHSHHLQAAVTVHTVDAEC", "length": 1222, "header": "tr|A0A8V0ZZU9-1|A0A8V0ZSJ7_CHICK Computationally mapped isoform of VWFA and cache domain-containing protein 1 OS=Gallus gallus OX=9031 GN=CACHD1 PE=3 SV=1 CANONICAL=A0A8V0ZSJ7-1" }, "locus": { "chromosome": "8", "start_pos": 27844442, "end_pos": 27765957, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010059662.1", "url": "https://www.ensembl.org/id/ENSGALT00010059662.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036443.1", "url": "https://www.ensembl.org/id/ENSGALP00010036443.1" } ] } }, { "isoform_ac": "A0A8V0ZZV6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSJ7/entry#A0A8V0ZZV6-1", "sequence": { "sequence": "MARGGGRLEAAARGRRPRGRGALGLLCLAVLCGLGAAEAEFSILEEAQVLATQMRKLATEELGVVTMQRIFNSFMYTEKISNGESEVQQLAKKIREKFNRYLDVVNRNKQVVEASYTAHLTSPLTAIQDCCTIPPSMMEFDGNFNTNVSRTISCDRLSTTVNSRAFNPGRDLNSVLADNLKSNPGIKWQYFSSEEGIFTVFPAHKFRCKGSYEHRSRPVYVSTVRPQSKHIVVIVDHGASVTETQLQIAKDAAQVILSSIDEHDKISVLTVADTVRTCSLDQCYKTFLSPATSETKRKMSTFVSSIKSSDSPTQHAIGFQKAFQLIRNTNNGTKLQGKGVTGLKELAFLRDLAEQNSVKYGVPDRTTLPVIKGSMMVLNQLSNLETTVGRFYTNLPNRMIDEAVFSLPFSDEMGDGLIMTVSKPCYFGNLLLGIVGVDVNLAYILEDVTYYQDSLGSYTFLIDNKGYTLMHPSLTRPYLLSEPPLHTDIIHYENIPKFELVRQNILSIPLGSQIITVPVNSSLSWHVNKLREVGKEAYNVSYAWKMVQDTSFILCVVVIQPEIPVKQLKNLNTVPSSKLLYHRLDLLGQPNACLHFKQLATLESPTVMLSAGSFSSPYEHLSQPETKRMVEHYTAYLSDNTRLIANPGLKFSVRNEVMATSHVTDEWMTQMEMSSYEQLNSYIVRRYIATPNGVLRIYPGSLMDKAFDPTRRQWYLHAVANPGLITFTGPYLDVGGAGYVVTISHTIHSSSAQMSSGHSVAVMGIDFTLRYFYKVLMDLLPVCNQDGGNKIRCFIMEDRGYLVAHPTLIDPKGHAPVEQQHITHKEPLVANDILNHPNFVKKNLCNSFSDRTVQRFYKFNTSLVGDLTNLVHGSHCSKYRLTRIPGTNAFVGIVNETCDSLAFCACSMVDRLCLNCHRMEQNECECPCECPLEVNECTGNLTNAESRNPSCEVHQEPMTFTAIDPSLQDALPQCINTQCNQRTESGDCFGVLDCEWCMVDSDGKTHLDKSYCAPQKECFGGIVGAKSPYVDDLGAIGDEVITLNMIKSAPVGPVAGGIMGCIMVLVLAVYAYRHQIHRRSHQHMSPLAAQEMSVRMSNLENDRDERDDDSHEDRGIISNTRFIAAVIERHAHSPERRRRYWGRSGTESDHGYSTMSPQEDSENPPCNNDPLSAGVDVGNHDEDLDLDTPPQTAALLSHKFHHYRLHHPTLHHSHHLQAAVTVHTVDAEC", "length": 1229, "header": "tr|A0A8V0ZZV6-1|A0A8V0ZSJ7_CHICK Computationally mapped isoform of VWFA and cache domain-containing protein 1 OS=Gallus gallus OX=9031 GN=CACHD1 PE=3 SV=1 CANONICAL=A0A8V0ZSJ7-1" }, "locus": { "chromosome": "8", "start_pos": 27844442, "end_pos": 27762581, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010059676.1", "url": "https://www.ensembl.org/id/ENSGALT00010059676.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036453.1", "url": "https://www.ensembl.org/id/ENSGALP00010036453.1" } ] } }, { "isoform_ac": "A0A8V1A1Q7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSJ7/entry#A0A8V1A1Q7-1", "sequence": { "sequence": "MRKLATEELGVVTMQRIFNSFMYTEKISNGESEVQQLAKKIREKFNRYLDVVNRNKQVVEASYTAHLTSPLTAIQDCCTIPPSMMEFDGNFNTNVSRTISCDRLSTTVNSRAFNPGRDLNSVLADNLKSNPGIKWQYFSSEEGIFTVFPAHKFRCKGSYEHRSRPVYVSTVRPQSKHIVVIVDHGASVTETQLQIAKDAAQVILSSIDEHDKISVLTVADTVRTCSLDQCYKTFLSPATSETKRKMSTFVSSIKSSDSPTQHAIGFQKAFQLIRNTNNGTKLQGNTDMVIISLSAGITSKDSSEDDKKATLRVINEENSFLNNSVMILTYALMNEGVTGLKELAFLRDLAEQNSVKYGVPDRTTLPVIKGSMMVLNQLSNLETTVGRFYTNLPNRMIDEAVFSLPFSDEMGDGLIMTVSKPCYFGNLLLGIVGVDVNLAYILEDVTYYQDSLGSYTFLIDNKGYTLMHPSLTRPYLLSEPPLHTDIIHYENIPKFELVRQNILSIPLGSQIITVPVNSSLSWHVNKLREVGKEAYNVSYAWKMVQDTSFILCVVVIQPEIPVKQLKNLNTVPSSKLLYHRLDLLGQPNACLHFKQLATLESPTVMLSAGSFSSPYEHLSQPETKRMVEHYTAYLSDNTRLIANPGLKFSVRNEVMATSHVTDEWMTQMEMSSYEQLNSYIVRRYIATPNGVLRIYPGSLMDKAFDPTRRQWYLHAVANPGLITFTGPYLDVGGAGYVVTISHTIHSSSAQMSSGHSVAVMGIDFTLRYFYKVLMDLLPVCNQDGGNKIRCFIMEDRGYLVAHPTLIDPKGHAPVEQQHITHKEPLVANDILNHPNFVKKNLCNSFSDRTVQRFYKFNTSLVGDLTNLVHGSHCSKYRLTRIPGTNAFVGIVNETCDSLAFCACSMVDRLCLNCHRMEQNECECPCECPLEVNECTGNLTNAESRNPSCEVHQEPMTFTAIDPSLQDALPQCINTQCNQRTESGDCFGVLDCEWCMVDSDGKTHLDKSYCAPQKECFGGIVGAKSPYVDDLGAIGDEVITLNMIKSAPVGPVAGGIMGCIMVLVLAVYAYRHQIHRRSHQHMSPLAAQEMSVRMSNLENDRDERDDDSHEDRGIISNTRFIAAVIERHAHSPERRRRYWGRSGTESDHASVISSSSEGCPFFFPSSANWKP", "length": 1170, "header": "tr|A0A8V1A1Q7-1|A0A8V0ZSJ7_CHICK Computationally mapped isoform of VWFA and cache domain-containing protein 1 OS=Gallus gallus OX=9031 GN=CACHD1 PE=3 SV=1 CANONICAL=A0A8V0ZSJ7-1" }, "locus": { "chromosome": "8", "start_pos": 27842810, "end_pos": 27762740, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010059668.1", "url": "https://www.ensembl.org/id/ENSGALT00010059668.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036447.1", "url": "https://www.ensembl.org/id/ENSGALP00010036447.1" } ] } }, { "isoform_ac": "A0A8V1A563-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSJ7/entry#A0A8V1A563-1", "sequence": { "sequence": "MVWLGMRLGSSEIVPQKTERIFNSFMYTEKISNGESEVQQLAKKIREKFNRYLDVVNRNKQVVEASYTAHLTSPLTAIQDCCTIPPSMMEFDGNFNTNVSRTISCDRLSTTVNSRAFNPGRDLNSVLADNLKSNPGIKWQYFSSEEGIFTVFPAHKFRCKGSYEHRSRPVYVSTVRPQSKHIVVIVDHGASVTETQLQIAKDAAQVILSSIDEHDKISVLTVADTVRTCSLDQCYKTFLSPATSETKRKMSTFVSSIKSSDSPTQHAIGFQKAFQLIRNTNNGTKLQGNTDMVIISLSAGITSKDSSEDDKKATLRVINEENSFLNNSVMILTYALMNEGVTGLKELAFLRDLAEQNSVKYGVPDRTTLPVIKGSMMVLNQLSNLETTVGRFYTNLPNRMIDEAVFSLPFSDEMGDGLIMTVSKPCYFGNLLLGIVGVDVNLAYILEDVTYYQDSLGSYTFLIDNKGYTLMHPSLTRPYLLSEPPLHTDIIHYENIPKFELVRQNILSIPLGSQIITVPVNSSLSWHVNKLREVGKEAYNVSYAWKMVQDTSFILCVVVIQPEIPVKQLKNLNTVPSSKLLYHRLDLLGQPNACLHFKQLATLESPTVMLSAGSFSSPYEHLSQPETKRMVEHYTAYLSDNTRLIANPGLKFSVRNEVMATSHVTDEWMTQMEMSSYEQLNSYIVRRYIATPNGVLRIYPGSLMDKAFDPTRRQWYLHAVANPGLITFTGPYLDVGGAGYVVTISHTIHSSSAQMSSGHSVAVMGIDFTLRYFYKVLMDLLPVCNQDGGNKIRCFIMEDRGYLVAHPTLIDPKGHAPVEQQHITHKEPLVANDILNHPNFVKKNLCNSFSDRTVQRFYKFNTSLVGDLTNLVHGSHCSKYRLTRIPGTNAFVGIVNETCDSLAFCACSMVDRLCLNCHRMEQNECECPCECPLEVNECTGNLTNAESRNPSCEVHQEPMTFTAIDPSLQDALPQCINTQCNQRTESGDCFGVLDCEWCMVDSDGKTHLDKSYCAPQKECFGGIVGAKSPYVDDLGAIGDEVITLNMIKSAPVGPVAGGIMGCIMVLVLAVYAYRHQIHRRSHQHMSPLAAQEMSVRMSNLENDRDERDDDSHEDRGIISNTRFIAAVIERHAHSPERRRRYWGRSGTESDHGYSTMSPQEDSENPPCNNDPLSAGVDVGNHDEDLDLDTPPQTAALLSHKFHHYRLHHPTLHHSHHLQAAVTVHTVDAEC", "length": 1230, "header": "tr|A0A8V1A563-1|A0A8V0ZSJ7_CHICK Computationally mapped isoform of VWFA and cache domain-containing protein 1 OS=Gallus gallus OX=9031 GN=CACHD1 PE=3 SV=1 CANONICAL=A0A8V0ZSJ7-1" }, "locus": { "chromosome": "8", "start_pos": 27844442, "end_pos": 27781451, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010059658.1", "url": "https://www.ensembl.org/id/ENSGALT00010059658.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036440.1", "url": "https://www.ensembl.org/id/ENSGALP00010036440.1" } ] } }, { "isoform_ac": "F1NML1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSJ7/entry#F1NML1-1", "sequence": { "sequence": "MARGGGRLEAAARGRRPRGRGALGLLCLAVLCGLGAAEAEFSILEEAQVLATQMRKLATEELGVVTMQRIFNSFMYTEKISNGESEVQQLAKKIREKFNRYLDVVNRNKQVVEASYTAHLTSPLTAIQDCCTIPPSMMEFDGNFNTNVSRTISCDRLSTTVNSRAFNPGRDLNSVLADNLKSNPGIKWQYFSSEEGIFTVFPAHKFRCKGSYEHRSRPVYVSTVRPQSKHIVVIVDHGASVTETQLQIAKDAAQVILSSIDEHDKISVLTVADTVRTCSLDQCYKTFLSPATSETKRKMSTFVSSIKSSDSPTQHAIGFQKAFQLIRNTNNGTKLQGNTDMVIISLSAGITSKDSSEDDKKATLRVINEENSFLNNSVMILTYALMNEGVTGLKELAFLRDLAEQNSVKYGVPDRTTLPVIKGSMMVLNQLSNLETTVGRFYTNLPNRMIDEAVFSLPFSDEMGDGLIMTVSKPCYFGNLLLGIVGVDVNLAYILEDVTYYQDSLGSYTFLIDNKGYTLMHPSLTRPYLLSEPPLHTDIIHYENIPKFELVRQNILSIPLGSQIITVPVNSSLSWHVNKLREVGKEAYNVSYAWKMVQDTSFILCVVVIQPEIPVKQLKNLNTVPSSKLLYHRLDLLGQPNACLHFKQLATLESPTVMLSAGSFSSPYEHLSQPETKRMVEHYTAYLSDNTRLIANPGLKFSVRNEVMATSHVTDEWMTQMEMSSYEQLNSYIVRRYIATPNGVLRIYPGSLMDKAFDPTRRQWYLHAVANPGLITFTGPYLDVGGAGYVVTISHTIHSSSAQMSSGHSVAVMGIDFTLRYFYKVLMDLLPVCNQDGGNKIRCFIMEDRGYLVAHPTLIDPKGHAPVEQQHITHKEPLVANDILNHPNFVKKNLCNSFSDRTVQRFYKFNTSLVGDLTNLVHGSHCSKYRLTRIPGTNAFVGIVNETCDSLAFCACSMVDRLCLNCHRMEQNECECPCECPLEVNECTGNLTNAESRNPSCEVHQEPMTFTAIDPSLQDALPQCINTQCNQRTESGDCFGVLDCEWCMVDSDGKTHLDKSYCAPQKECFGGIVGAKSPYVDDLGAIGDEVITLNMIKSAPVGPVAGGIMGCIMVLVLAVYAYRHQIHRRSHQHMSPLAAQEMSVRMSNLENDRDERDDDSHEDRGIISNTRFIAAVIERHAHSPERRRRYWGRSGTESDHGYSTMSPQEDSENPPCNNDPLSAGVDVGNHDEDLDLDTPPQTAALLSHKFHHYRLHHPTLHHSHHLQAAVTVHTVDAEC", "length": 1279, "header": "tr|F1NML1-1|A0A8V0ZSJ7_CHICK Computationally mapped isoform of VWFA and cache domain-containing protein 1 OS=Gallus gallus OX=9031 GN=CACHD1 PE=3 SV=3 CANONICAL=A0A8V0ZSJ7-1" }, "locus": { "chromosome": "8", "start_pos": 27844442, "end_pos": 27762581, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010059678.1", "url": "https://www.ensembl.org/id/ENSGALT00010059678.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036455.1", "url": "https://www.ensembl.org/id/ENSGALP00010036455.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 82, "start_aa": "Thr", "end_pos": 82, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr82", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:424693", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424693", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6A388-1", "protein_name": "VWFA and cache domain-containing protein 1", "gene_name": "Cachd1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAREPEEEETVRTAALVRRCPRCPGWPGAPRPPFWLLCLVACWILGAVADADFSILDEAQVLASQMRRLAAEELGVVTMQRIFNSLVYTEKISNGESEVQQLAKKIREKFNRYLDVVNRNKQVVEASYTAHLTSPLTAIQDCCTIPPSMMEFDGNFNTNVSRTVSCDRLSTTVNSRAFNPGRDLNSVLADNLKSNPGIKWQYFSSEEGIFTVFPAHKFRCKGSYEHRSRPIYVSTVRPQSKHIVVILDHGASVTDTQLQIAKDAAQVILSAIDEHDKISVLTVADTVRTCSLDQCYKTYLSPATSETKRKMSTFVSSVKPSDSPTQHAVGFHRAFQLIRSTSNNTRFQANTDMVIIYLSAGITSKDSSEEDKKATLRVINEENGFLNNSVMILTYALMNDGVTGLKELAFLRDLAEQNSGKYGIPDRTALPVIKGSMMVLNQLSNLETTVGRFYTNLPNRMIDEAVFSLPFSDEMGDGLIMTVSKPCYFGNLLLGIVGVDVNLAYILEDVTYYQDSLASYTFLIDDKGYTLMHPSLTRPYLLSEPPLHTDIIHYENIPKFELVRQNILSLPLGSQIITVPVNSSLSWHINKLRETGKEAYNVSYAWKMVQDTSFILCIVVIQPEIPVKQLKNLNTVPSSKLLYHRLDLLGQPSACLHFKQLATLESPTVMLSAGSFSSPYEHLSQPETKRMVEHYTAYLSDNTRLIANPGLKFSVRNEVMATSHVTDEWMTQMEMSSLNTYIVRRYIATPNGVLRIYPGSLMDKAFDPTRRQWYLHAVANPGLISLTGPYLDVGGAGYVVTISHTIHSSSTQLSSGHTVAVMGIDFTLRYFYKVLMDLLPVCNQDGGNKIRCFIMEDRGYLVAHPTLVDPKGHAPLEQQHITHKEPLVANDILNHPNFVKKNLCNSFSDRTVQRSYKFNTSLVGDLTNLVHGSHCSKYRLTRIPGTNAFVGIVNETCDSLAFCACSMVDRLCLNCHRMEQNECECPCECPLEVNECTGNLTNAENRNPSCEVHQEPVTYTAIDPGLQDALHQCVNSRCNQRMESGDCFGVLDCEWCVVDSDGKTHLDKSYCAPQKECFGGIVGAKSPYVDDMGAIGDEVITLNMIKSAPVGPVAGGIMGCIMVLVLAVYAYRHQIHRRSHQHMSPLAAQEMSVRMSNLENDRDEREDDSHEDRGIISNTRFIAAVMERHAHSPERRRRYWGRSGTESDHGYSTMSPQEDSENPPCNNDPLSAGVDVGNHDDDLDLDTPPQTAALLSHKFHHYRSHHPTLHHSHHLQAAVTVHTVDAEC", "length": 1288 }, "evidence": [ { "id": "A0A8V0ZSJ7", "url": "https://omabrowser.org/oma/group/A0A8V0ZSJ7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E7F5Q0-1", "protein_name": "VWFA and cache domain-containing protein 1", "gene_name": "cachd1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MASRSRTGPRFSFAAWSKHSRPNWNNLEISKWSLVALLVFACCGFCGADSEFSILEEAQVLAVQMKKLSTQELGVLTMQRIFNSFVYTEKTSNGETEVQQLAKKIREKFNRYLDVVNRNKQVVEASYTAHLTSPLTAIQDCCSIPPSMMEFDGNFNANVSKTVSCDRLSPTVNSRAFNPGRDLNSVLADNLKSNPGIKWQYFSSEEGIFTLFPAHKFHCKGTFEHRSRPVYVAAVRPQSKHIVVIIDHGASVTETQLQIARDAALVILNSIDEHDKISVLTIADTVRSCSLDQCYKSFLSPATSETKRKMSTFISNIKASDSSTQHAVGFQKAFQLLRNTSNVTRQLTNTDMMIIYLSSGITSRDSSEHEKRATLSAVKEENRHLNNSVMILTYALMNDGVTGLKELAFLRDLAEQNSLKYGVQDRSALPVVKGSMMVLNQLSNLETTVGRFYINLPNRMIDVATFSLPYADQMGDGFIMTVSRPCYFGNLLLGVVGVDVNLAYILEDVTYYQDSLASYTFLIDNKGYTLMHPSLTRPYLMTEAPLHTDIIHYENIPGFPVVRQNILSLPLGSQVIAVPVNSSLSWHMNRLRDPNRDAYNVSYAWKLVQDTSFILCIVYVQPEIPVKQLKNLNTAPSSKLLYHRLDLLGQPSSCLHFKQLATVESPTVMLSAGSFSSPYEHLSQPETKRMVEHYTAYLSDNTRLIANPGLKSSVRNEVMATSHVTDEWMSLMEMSSLNCYIVRRYIATPNGVLRIYPGSLMDKAFDPTRRQWYLHAVANPGLITFTGPYLDVGGAGYVVTISHTIHAPSSQMASGYTVAVMGIDFTLRYFYKVLLDLLPICNQDKGNKIRCFIMEDRGYLVAHPTLIDPKGHAPAEQQHITHKEPLVANDILNHPNFVKKNLCNSFSDRTVQRFYKFNTSIVGDLTNLVHGSHCSKYRLTRIPGTNAFAGIVNETCDALAFCACSTVDRLCLNCHRMEQNECECPCECPLEVNECTGNLTNAENRNPSCDVHQEPLSLTVIEPSLQDTLPQCINTRCSQRFTSSDCFGVLDCEWCMVDSDGKTHLDKPYCALQKECFGGIVGAKSPYVDGMGILDEELASLNMIKSAPVGPVAGGIMGCIMVLVLAVYAYRHQIHRRSHQHMSPLAAQEMSVRMSNLDNERDDRDEDSHEDRGIISNTRFIAAVIERHTHSPERRRRYWGRSGTESDHGYSTMSPQEDSENPPCNNDPLSAGVDVGNHDEDLDLDTPPQTAALLSHKFHPYRHPHMHHPLHLHTHHLQAAVTVHSVDAEC", "length": 1290 }, "evidence": [ { "id": "A0A8V0ZSJ7", "url": "https://omabrowser.org/oma/group/A0A8V0ZSJ7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1N4N7-1", "protein_name": "VWFA and cache domain-containing protein 1", "gene_name": "CACHD1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTREPEEEEAAGAAALARGSRGSLGRIQARRPPLWLLCLAVGWLLGAGADAEFSILDEAQVLASQMRRLAAEELGVVTMQRIFNSFVYTEKISNGESEVQQLAKKIREKFNRYLDVVNRNKQVVEASYTAHLTSPLTAIQDCCTIPPSMMEFDGNFNTNVSRTISCDRLSTTVNSRAFNPGRDLNSVLADNLKSNPGIKWQYFSSEEGIFTVFPAHKFRCKGSYEHRSRPIYVSTVRPQSKQVVVILDHGASVTDTQLQIAKDAAQVILSAIDEHDKISVLTVADTVRTCSLDQCYKTFLSPATSETKRKMSTFVSSVKSLDSPTQHAVGFQKAFQLIRSTNNSTKFQANTDMVIIYLSAGITSKDSSEEDKKATLRVINEENSFLNNSVMILTYALMNDGVTGLKELAFLRDLAEQNSGKYGVLDRIALPVIKGSMMVLNQLSNLETTVGRFYTNLPNRMIDEAVFSLPFSDEMGDGLIMTVSKPCYFGNLLLGIVGVDVNLAYILEDVTYYQDSLASYTFLIDDKGYTLMHPSLTRPYLLSEPPLHTDIIHYENIPKFELVRQNILSLPLGSQIIAVPVNSSLSWHINKLRETGKEAYNVSYAWKMVQDTSFILCIVVIQPEIPVKQLKNLNTVPSSKLLYHRLDLLGQPSACLHFKQLATLESPTVMLSAGSFSSPYEHLSQPETKRMVEHYTAYLSDNTRLIANPGLKFSVRNEVMATSHVTDEWMTQMEMSSLNTYIVRRYIATPNGVLRIYPGSLMDKAFDPTRRQWYLHAVANPGLISLTGPYLDVGGAGYVVTISHTIHSSSTQLSSGHTVAVMGIDFTLRYFYKVLMDLLPVCNQDGGNKIRCFIMEDRGYLVAHPTLIDPKGHAPVEQQHITHKEPLVANDILNHPNFVKKNLCNSFSDRTVQRFYKFNTSLVGDLTNLVHGSHCSKYRLARIPGTNAFVGIVNETCDSLAFCACSMVDRLCLNCHRMEQNECECPCECPLEVNECTGNLTNAENRNPSCEVHQEPVTYTAIDPGLQDALHQCVNSRCSQRTESGDCFGVLDCEWCMVDSDGKTHLDKSYCAPQKECFGGIVGAKSPYVDDMGSIGDEVVTLNMIKSAPVGPVAGGIMGCIMVLVLAVYAYRHQIHRRSHQHMSPLAAQEMSVRMSNLENDRDERDDDGPEDRGIISNTRFIAAVIERHAHSPERRRRYWGRSGTESDHGYSTMSPQEDSENPPCTNDPLSAGVDVGNHDEDLELDTPPQTAALLSHKFHHYRLHHPTLHHSHHLQAAVTVHTVDAEC", "length": 1288 }, "evidence": [ { "id": "A0A8V0ZSJ7", "url": "https://omabrowser.org/oma/group/A0A8V0ZSJ7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q5BI42-1", "protein_name": "VWFA and cache domain-containing protein CG16868", "gene_name": "", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MWPNSNLNAVLLILAVLACPTSSQHVPLAMANSTSNQVPTDPGFMPLQQSPGSVFFVHHNQQNAMQLRHSMEGKLRNIRNTELRVAKIQEIFDSMHFSSAKGASNTRQASSNDSNVVNPQLQRDLQLFSERLSKKIQKATYVVLELRELLRYNLTKVWQYSYDDEDDESESEMDLEMELEDLHARNTASPTDEHVQLYLNTQIESCQPDYETDLEYGSSSTQSIHYNRQQIQILNYLKSDDARATFLNENNARSLAVNGYISNQLVLLKRRLSRSDAENSNSKPISGNHFKHIYFLSNSDGASASLHFRQLYVSAIKQKFVLFLIDVGSALSAELFDLSKSFVHEMLQLLEDTDKVSLVTVASEANFMSLEAFPAEAGHGIYSATRAHKEEIISFINSLSRAQAFTNHSLGFEYSFELLHRLQQSGMINTAEQPVEFVYITRGLLTNLSDAMAVLRVVADGQRRLRAPVIINTCAVVLDEKRIMYEKQFLNDVASQNYTKYEIDVASWWPSGQEASELVGRFYVLSKMHAETSLPQTSSRIFGPLFQERYLSDTLEVHPPVVDADSGDVLVSITHAVPPYGVVGVNLYLSDLLEDLLNYPSTTSSAKQGLGYAFLLDRSTGNTLAHPAFPRPLIQRETSYPVNIAYLENATDFSSHIRDRLLREESGNVTTDVYVGRQRLQRTYYWQSVLGFYVLCLVSSGGDTLRNVSSTQRYNLKDTVSNYEPGYYGESMDLLYHRLDLNQGGSAPPKTCRYFRQVATMDAPTLFLSAAAFESPFGFLHNNRPRTQLRHVESIMAYLRDSSGLLANMGLRPSIRHEVGVLYQAMQQLRRRHQDARGSLRSHVIRRYIASVSGVLQLYPGCLLSSSYDPTRRPWFRQAIAQPGKIVSTAPYLDAGGAGYIITIAHTIFEGKAHALHSAQQDRPVAVVALDVPYAFYYRLILEGTPICQLPHIKCLLFEHEGYLLAHPSMLQPATLTKNQRRPHEHLTHKESYLANDMLNHGQLVRKLGCASYQNRTLQRYYAFNTSLSSILGNVVHGERTKYAIALIRGSNLFAAVLNSSCDGGAFCPCSTIDRECLNCKRMDQTDCECPCECPMVGDSSSPSSLMYFANYTRQFPYCPPPSEHFIALPPTTQLLSTLPNCPGSAGICETYSTQRECLGVMGCEWCQLDVDGNSFSTSFCSSQASCFNGVLASLTPYGELDEMELLAAHNPQREQHAYSAFGPLGGAIVVLVMVIGFAIYCYRHNLDAQTQEHFYVDSVQEENYGLPLSRFNFDDCKAHDEPPLGGGYDHASAQRQLMHAADISPYHVSSGSSYRRPPNGESDHGYSTMTPHEDSSDQQCFTLAEPLLLHDKRHSKSDTMSISTSISSPTNRQQSSSQPNTHPYLSNQPTSKTERYKQVQATPSPCRGTPAGGSVYGQTTLPLEGDKTRPHYILAPVTVHRHMETAES", "length": 1449 }, "evidence": [ { "id": "A0A8V0ZSJ7", "url": "https://omabrowser.org/oma/group/A0A8V0ZSJ7/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q5VU97-1", "protein_name": "VWFA and cache domain-containing protein 1", "gene_name": "CACHD1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MARQPEEEETAVARARRPPLWLLCLVACWLLGAGAEADFSILDEAQVLASQMRRLAAEELGVVTMQRIFNSFVYTEKISNGESEVQQLAKKIREKFNRYLDVVNRNKQVVEASYTAHLTSPLTAIQDCCTIPPSMMEFDGNFNTNVSRTISCDRLSTTVNSRAFNPGRDLNSVLADNLKSNPGIKWQYFSSEEGIFTVFPAHKFRCKGSYEHRSRPIYVSTVRPQSKHIVVILDHGASVTDTQLQIAKDAAQVILSAIDEHDKISVLTVADTVRTCSLDQCYKTFLSPATSETKRKMSTFVSSVKSSDSPTQHAVGFQKAFQLIRSTNNNTKFQANTDMVIIYLSAGITSKDSSEEDKKATLQVINEENSFLNNSVMILTYALMNDGVTGLKELAFLRDLAEQNSGKYGVPDRMALPVIKGSMMVLNQLSNLETTVGRFYTNLPNRMIDEAVFSLPFSDEMGDGLIMTVSKPCYFGNLLLGIVGVDVNLAYILEDVTYYQDSLASYTFLIDDKGYTLMHPSLTRPYLLSEPPLHTDIIHYENIPKFELVRQNILSLPLGSQIIAVPVNSSLSWHINKLRETGKEAYNVSYAWKMVQDTSFILCIVVIQPEIPVKQLKNLNTVPSSKLLYHRLDLLGQPSACLHFKQLATLESPTIMLSAGSFSSPYEHLSQPETKRMVEHYTAYLSDNTRLIANPGLKFSVRNEVMATSHVTDEWMTQMEMSSLNTYIVRRYIATPNGVLRIYPGSLMDKAFDPTRRQWYLHAVANPGLISLTGPYLDVGGAGYVVTISHTIHSSSTQLSSGHTVAVMGIDFTLRYFYKVLMDLLPVCNQDGGNKIRCFIMEDRGYLVAHPTLIDPKGHAPVEQQHITHKEPLVANDILNHPNFVKKNLCNSFSDRTVQRFYKFNTSLAGDLTNLVHGSHCSKYRLARIPGTNAFVGIVNETCDSLAFCACSMVDRLCLNCHRMEQNECECPCECPLEVNECTGNLTNAENRNPSCEVHQEPVTYTAIDPGLQDALHQCVNSRCSQRLESGDCFGVLDCEWCMVDSDGKTHLDKPYCAPQKECFGGIVGAKSPYVDDMGAIGDEVITLNMIKSAPVGPVAGGIMGCIMVLVLAVYAYRHQIHRRSHQHMSPLAAQEMSVRMSNLENDRDERDDDSHEDRGIISNTRFIAAVIERHAHSPERRRRYWGRSGTESDHGYSTMSPQEDSENPPCNNDPLSAGVDVGNHDEDLDLDTPPQTAALLSHKFHHYRSHHPTLHHSHHLQAAVTVHTVDAEC", "length": 1274 }, "evidence": [ { "id": "A0A8V0ZSJ7", "url": "https://omabrowser.org/oma/group/A0A8V0ZSJ7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6PDJ1-1", "protein_name": "VWFA and cache domain-containing protein 1", "gene_name": "Cachd1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAREPEEEETVRPAAVVRRCPRCPGWPGAPRPPLWLLCLVACWILGAVADADFSILDEAQVLASQMRRLAAEELGVVTMQRIFNSLVYTEKISNGESEVQQLAKKIREKFNRYLDVVNRNKQVVEASYTAHLTSPLTAIQDCCTIPPSMMEFDGNFNTNVSRTVSCDRLSTTVNSRAFNPGRDLNSVLADNLKSNPGIKWQYFSSEEGIFTVFPAHKFRCKGSYEHRSRPIYVSTVRPQSKHIVVILDHGASVTDTQLQIAKDAAQVILSAIDEHDKISVLTVADAVRTCSLDQCYKTYLSPATSETKRKMSTFVSSVKPSDSPTQHAVGFHRAFQLIRSTSNSTRFQANTDMVIIYLSAGITSKDSSEEDKKATLRVINEENGFLNNSVMILTYALMNDGVTGLKELAFLRDLAEQNSGKYGIPDRTALPVIKGSMMVLNQLSNLETTVGRFYTNLPNRMIDEAVFSLPFSDEMGDGLIMTVSKPCYFGNLLLGIVGVDVNLAYILEDVTYYQDSLASYTFLIDDKGYTLMHPSLTRPYLLSEPPLHTDIIHYENIPKFELVRQNILSLPLGSQIITVPVNSSLSWHINKLRETGKEAYNVSYAWKMVQDTSFILCIVVIQPEIPVKQLKNLNTVPSSKLLYHRLDLLGQPSACLHFKQLATLESPTVMLSAGSFSSPYEHLSQPETKRMVEHYTAYLSDNTRLIANPGLKFSVRNEVMATSHVTDEWMTQMEMSSLNTYIVRRYIATPNGVLRIYPGSLMDKAFDPTRRQWYLHAVANPGLISLTGPYLDVGGAGYVVTISHTIHSSSTQLSSGHTVAVMGIDFTLRYFYKVLMDLLPVCNQDGGNKIRCFIMEDRGYLVAHPTLVDPKGHAPLEQQHITHKEPLVANDILNHPNFVKKNLCNSFSDRTVQRSYKFNTSLVGDLTNLVHGSHCSKYRLTRIPGTNAFVGIVNETCDSLAFCACSMVDRLCLNCHRMEQNECECPCECPLEVNECTGNLTNAENRNPSCEVHQEPVTYTAIDPGLQDALQQCVNSRCNQRMESGDCFGVLDCEWCVVDSDGKTHLDKSYCAPQKECFGGIVGAKSPYVDDMGAIGDEVITLNMIKSAPVGPVAGGIMGCIMVLVLAVYAYRHQIHRRSHQHMSPLAAQEMSVRMSNLENDRDERDDDSHEDRGIISNTRFIAAVMERHVHSPERRRRYWGRSGTESDHGYSTMSPQEDSENPPCNNDPLSAGVDVGNHDDDLDLDTPPQTAALLSHKFHHYRPHHPTLHHSHHLQAAVTVHTVDAEC", "length": 1288 }, "evidence": [ { "id": "A0A8V0ZSJ7", "url": "https://omabrowser.org/oma/group/A0A8V0ZSJ7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSJ7" } ], "pmid": "" }, { "name": "voltage-gated calcium channel complex", "id": "GO:0005891", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005891", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSJ7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "calcium ion transport", "id": "GO:0006816", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006816", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSJ7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "voltage-gated calcium channel activity", "id": "GO:0005245", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005245", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSJ7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1029, "end_pos": 1031, "annotation": "n_glycosylation_sequon" }, { "start_pos": 186, "end_pos": 188, "annotation": "n_glycosylation_sequon" }, { "start_pos": 370, "end_pos": 372, "annotation": "n_glycosylation_sequon" }, { "start_pos": 414, "end_pos": 416, "annotation": "n_glycosylation_sequon" }, { "start_pos": 609, "end_pos": 611, "annotation": "n_glycosylation_sequon" }, { "start_pos": 628, "end_pos": 630, "annotation": "n_glycosylation_sequon" }, { "start_pos": 949, "end_pos": 951, "annotation": "n_glycosylation_sequon" }, { "start_pos": 984, "end_pos": 986, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZSJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSJ7" }, { "id": "PS50234", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50234" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "VWFA", "eco_id": "ECO_0000259", "start_pos": 269, "end_pos": 470, "start_aa": "His", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 82 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1029, "end_pos": 1031 }, { "start_pos": 186, "end_pos": 188 }, { "start_pos": 370, "end_pos": 372 }, { "start_pos": 414, "end_pos": 416 }, { "start_pos": 609, "end_pos": 611 }, { "start_pos": 628, "end_pos": 630 }, { "start_pos": 949, "end_pos": 951 }, { "start_pos": 984, "end_pos": 986 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": 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{ "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZSK0-1", "uniprot_ac": "A0A8V0ZSK0", "uniprot_id": "A0A8V0ZSK0_CHICK", "mass": { "chemical_mass": 64190.0, "monoisotopic_mass": 64190.0 }, "refseq": {}, "gene_names": [ { "name": "INSC", "type": "recommended", "evidence": [ { "id": "A0A8V0ZSK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSK0" } ] } ], "protein_names": [ { "name": "INSC spindle orientation adaptor protein", "type": "synonym", "evidence": [ { "id": "A0A8V0ZSK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSK0/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSK0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSK0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "INSC", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSK0", "locus": { "chromosome": "5", "start_pos": 10349862, "end_pos": 10230728, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022949", "url": "https://www.ensembl.org/id/ENSGALG00010022949" } ] } } ], "crossref": [ { "id": "A0A8V0ZSK0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZSK0", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd21966", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21966", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "423067", "url": "https://www.ncbi.nlm.nih.gov/gene/423067", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000225", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000225", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031938", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031938", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038205", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038205", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039921", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039921", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045789", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045789", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "SAITERC", "url": "https://omabrowser.org/oma/group/SAITERC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZKC3", "url": "https://www.orthodb.org/?gene=A0A8V0ZKC3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZKC6", "url": "https://www.orthodb.org/?gene=A0A8V0ZKC6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZSK0", "url": "https://www.orthodb.org/?gene=A0A8V0ZSK0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZTI1", "url": "https://www.orthodb.org/?gene=A0A8V0ZTI1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZTJ5", "url": "https://www.orthodb.org/?gene=A0A8V0ZTJ5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZY39", "url": "https://www.orthodb.org/?gene=A0A8V0ZY39", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21386", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21386", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21386:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21386:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF16748", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16748", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19427", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19427", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZKC3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKC3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKC3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKC3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKC6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKC6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKC6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKC6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZSK0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSK0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZSK0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSK0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZTI1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTI1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZTI1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTI1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZTJ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTJ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZTJ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTJ5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZY39", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZY39", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZY39-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZY39-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKSFCYRKWIVDRDVQMLLSSFLAADCDLWRRIHKGINMAFKGEDHLDSLPLPVQRMHLIQVDSVQRWMEDLKLMTDCECMCILQSKPISAEKDEQNELILSSQYSTSDNLQLLLKRAWIISTELTKIAQKLEKNRWQRVHSMTVRVNCHVRSMINEYNAFTRSSSEEMNQLEKLLIDKCSEFTAFTERCIQIEDEQMLRSMKSCINETLTTVAQYFGQLIELVLTHEAQNLLRQIESSDSVYITESAINSLFSLTQEGTHLCRIIAKEGGVVALFKICRQDYFRCLYPQTLRTLASICCVEEGMHQLEKVDGILCLADILTDNTHSEATHAEAAAVIAQITSPHLTFTQHLSSFLENMEEIVTALVKLCQEASSGEVFLLASAALANITFFDTMACEMLLQLNAMKILLAACSDKHIVDTPYSRDQVVTILANMSVLDQCASEIIQGNGVQLLMEMLFERSSSGNSAEVAACERVQQKSAVTLARLSRDPEVADAAVKLSCIPRLIKLCRSPTERNNSDSVLVACLAALRRLAVMSPEGLEDSDFQQLVKPRLVDSFLLCTNMEESFV", "length": 569, "header": "tr|A0A8V0ZSK0-1|A0A8V0ZSK0_CHICK Isoform 1 of INSC spindle orientation adaptor protein OS=Gallus gallus OX=9031 GN=INSC PE=4 SV=1 CANONICAL=A0A8V0ZSK0-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZKC3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSK0/entry#A0A8V0ZKC3-1", "sequence": { "sequence": "MYCDLWRRIHKGINMAFKGEDHLDSLPLPVQRMHLIQVDSVQRWMEDLKLMTDCECMCILQSKPISAEKDEQNELILSSQYSTSDNLQLLLKRAWIISTELTKIAQKLEKNRWQRVHSMTVRVNCHVRSMINEYNAFTRSSSEEMNQLEKLLIDKCSEFTAFTERCIQIEDEQMLRSMKSCINETLTTVAQYFGQLIELVLTHEAQNLLRQIESSDSVYITESAINSLFSLTQEGTHLCRIIAKEGGVVALFKICRQDYFRCLYPQTLRTLASICCVEEGMHQLEKVDGILCLADILTDNTHSEATHAEAAAVIAQITSPHLTFTQHLSSFLENMEEIVTALVKLCQEASSGEVFLLASAALANITFFDTMACEMLLQLNAMKILLAACSDKHIVDTPYSRDQVVTILANMSVLDQCASEIIQGNGVQLLMEMLFERSSSGNSAEVAACERVQQKSAVTLARLSRDPEVADAAVKLSCIPRLIKLCRSPTERNNSDSVLVACLAALRRLAVMSPEGLEDSDFQQLVKPRLVDSFLLCTNMEESFV", "length": 545, "header": "tr|A0A8V0ZKC3-1|A0A8V0ZKC3_CHICK Computationally mapped isoform of INSC spindle orientation adaptor protein OS=Gallus gallus OX=9031 GN=INSC PE=4 SV=1 CANONICAL=A0A8V0ZSK0-1" }, "locus": { "chromosome": "5", "start_pos": 10349144, "end_pos": 10235581, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055865.1", "url": "https://www.ensembl.org/id/ENSGALT00010055865.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033818.1", "url": "https://www.ensembl.org/id/ENSGALP00010033818.1" } ] } }, { "isoform_ac": "A0A8V0ZKC6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSK0/entry#A0A8V0ZKC6-1", "sequence": { "sequence": "MAFKGEDHLDSLPLPVQRMHLIQVDSVQRWMEDLKLMTDCECMCILQSKPISAEKDEQNELILSSQYSTSDNLQLLLKRAWIISTELTKIAQKLEKNRWQRVHSMTVRVNCHVRSMINEYNAFTRSSSEEMNQLEKLLIDKCSEFTAFTERCIQIEDEQMLRSMKSCINETLTTVAQYFGQLIELVLTHEAQNLLRQIESSDSVYITESAINSLFSLTQEGTHLCRIIAKEGGVVALFKICRQDYFRCLYPQTLRTLASICCVEEGMHQLEKVDGILCLADILTDNTHSEATHAEAAAVIAQITSPHLTFTQHLSSFLENMEEIVTALVKLCQEASSGEVFLLASAALANITFFDTMACEMLLQLNAMKILLAACSDKHIVDTPYSRDQVVTILANMSVLDQCASEIIQGNGVQLLMEMLFERSSSGNSAEVAACERVQQKSAVTLARLSRDPEVADAAVKLSCIPRLIKLCRSPTERNNSDSVLVACLAALRRLAVMSPEGLEDSDFQQLVKPRLVDSFLLCTNMEESFV", "length": 531, "header": "tr|A0A8V0ZKC6-1|A0A8V0ZKC6_CHICK Computationally mapped isoform of INSC spindle orientation adaptor protein OS=Gallus gallus OX=9031 GN=INSC PE=4 SV=1 CANONICAL=A0A8V0ZSK0-1" }, "locus": { "chromosome": "5", "start_pos": 10349144, "end_pos": 10267870, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055873.1", "url": "https://www.ensembl.org/id/ENSGALT00010055873.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033823.1", "url": "https://www.ensembl.org/id/ENSGALP00010033823.1" } ] } }, { "isoform_ac": "A0A8V0ZSK0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSK0/entry#A0A8V0ZSK0-1", "sequence": { "sequence": "MKSFCYRKWIVDRDVQMLLSSFLAADCDLWRRIHKGINMAFKGEDHLDSLPLPVQRMHLIQVDSVQRWMEDLKLMTDCECMCILQSKPISAEKDEQNELILSSQYSTSDNLQLLLKRAWIISTELTKIAQKLEKNRWQRVHSMTVRVNCHVRSMINEYNAFTRSSSEEMNQLEKLLIDKCSEFTAFTERCIQIEDEQMLRSMKSCINETLTTVAQYFGQLIELVLTHEAQNLLRQIESSDSVYITESAINSLFSLTQEGTHLCRIIAKEGGVVALFKICRQDYFRCLYPQTLRTLASICCVEEGMHQLEKVDGILCLADILTDNTHSEATHAEAAAVIAQITSPHLTFTQHLSSFLENMEEIVTALVKLCQEASSGEVFLLASAALANITFFDTMACEMLLQLNAMKILLAACSDKHIVDTPYSRDQVVTILANMSVLDQCASEIIQGNGVQLLMEMLFERSSSGNSAEVAACERVQQKSAVTLARLSRDPEVADAAVKLSCIPRLIKLCRSPTERNNSDSVLVACLAALRRLAVMSPEGLEDSDFQQLVKPRLVDSFLLCTNMEESFV", "length": 569, "header": "tr|A0A8V0ZSK0-1|A0A8V0ZSK0_CHICK Isoform 1 of INSC spindle orientation adaptor protein OS=Gallus gallus OX=9031 GN=INSC PE=4 SV=1 CANONICAL=A0A8V0ZSK0-1" }, "locus": { "chromosome": "5", "start_pos": 10349144, "end_pos": 10260049, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055853.1", "url": "https://www.ensembl.org/id/ENSGALT00010055853.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033812.1", "url": "https://www.ensembl.org/id/ENSGALP00010033812.1" } ] } }, { "isoform_ac": "A0A8V0ZTI1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSK0/entry#A0A8V0ZTI1-1", "sequence": { "sequence": "MEIKDCDLWRRIHKGINMAFKGEDHLDSLPLPVQRMHLIQVDSVQRWMEDLKLMTDCECMCILQSKPISAEKDEQNELILSSQYSTSDNLQLLLKRAWIISTELTKIAQKLEKNRWQRVHSMTVRVNCHVRSMINEYNAFTRSSSEEMNQLEKLLIDKCSEFTAFTERCIQIEDEQMLRSMKSCINETLTTVAQYFGQLIELVLTHEAQNLLRQIESSDSVYITESAINSLFSLTQEGTHLCRIIAKEGGVVALFKICRQDYFRCLYPQTLRTLASICCVEEGMHQLEKVDGILCLADILTDNTHSEATHAEAAAVIAQITSPHLTFTQHLSSFLENMEEIVTALVKLCQEASSGEVFLLASAALANITFFDTMACEMLLQLNAMKILLAACSDKHIVDTPYSRDQVVTILANMSVLDQCASEIIQGNGVQLLMEMLFERSSSGNSAEVAACERVQQKSAVTLARLSRDPEVADAAVKLSCIPRLIKLCRSPTERNNSDSVLVACLAALRRLAVMSPEGLEDSDFQQLVKPRLVDSFLLCTNMEESFV", "length": 548, "header": "tr|A0A8V0ZTI1-1|A0A8V0ZTI1_CHICK Computationally mapped isoform of INSC spindle orientation adaptor protein OS=Gallus gallus OX=9031 GN=INSC PE=4 SV=1 CANONICAL=A0A8V0ZSK0-1" }, "locus": { "chromosome": "5", "start_pos": 10349144, "end_pos": 10243501, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055860.1", "url": "https://www.ensembl.org/id/ENSGALT00010055860.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033816.1", "url": "https://www.ensembl.org/id/ENSGALP00010033816.1" } ] } }, { "isoform_ac": "A0A8V0ZTJ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSK0/entry#A0A8V0ZTJ5-1", "sequence": { "sequence": "MKRAFIKWIVDRDVQMLLSSFLAADCDLWRRIHKGINMAFKGEDHLDSLPLPVQRMHLIQVDSVQRWMEDLKLMTDCECMCILQSKPISAEKDEQNELILSSQYSTSDNLQLLLKRAWIISTELTKIAQKLEKNRWQRVHSMTVRVNCHVRSMINEYNAFTRSSSEEMNQLEKLLIDKCSEFTAFTERCIQIEDEQMLRSMKSCINETLTTVAQYFGQLIELVLTHEAQNLLRQIESSDSVYITESAINSLFSLTQEGTHLCRIIAKEGGVVALFKICRQDYFRCLYPQTLRTLASICCVEEGMHQLEKVDGILCLADILTDNTHSEATHAEAAAVIAQITSPHLTFTQHLSSFLENMEEIVTALVKLCQEASSGEVFLLASAALANITFFDTMACEMLLQLNAMKILLAACSDKHIVDTPYSRDQVVTILANMSVLDQCASEIIQGNGVQLLMEMLFERSSSGNSAEVAACERVQQKSAVTLARLSRDPEVADAAVKLSCIPRLIKLCRSPTERNNSDSVLVACLAALRRLAVMSPEGLEDSDFQQLVKPRLVDSFLLCTNMEESFV", "length": 568, "header": "tr|A0A8V0ZTJ5-1|A0A8V0ZTJ5_CHICK Computationally mapped isoform of INSC spindle orientation adaptor protein OS=Gallus gallus OX=9031 GN=INSC PE=4 SV=1 CANONICAL=A0A8V0ZSK0-1" }, "locus": { "chromosome": "5", "start_pos": 10349144, "end_pos": 10230796, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055876.1", "url": "https://www.ensembl.org/id/ENSGALT00010055876.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033826.1", "url": "https://www.ensembl.org/id/ENSGALP00010033826.1" } ] } }, { "isoform_ac": "A0A8V0ZY39-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSK0/entry#A0A8V0ZY39-1", "sequence": { "sequence": "MSHQEQLLPNGTSDCDLWRRIHKGINMAFKGEDHLDSLPLPVQRMHLIQVDSVQRWMEDLKLMTDCECMCILQSKPISAEKDEQNELILSSQYSTSDNLQLLLKRAWIISTELTKIAQKLEKNRWQRVHSMTVRVNCHVRSMINEYNAFTRSSSEEMNQLEKLLIDKCSEFTAFTERCIQIEDEQMLRSMKSCINETLTTVAQYFGQLIELVLTHEAQNLLRQIESSDSVYITESAINSLFSLTQEGTHLCRIIAKEGGVVALFKICRQDYFRCLYPQTLRTLASICCVEEGMHQLEKVDGILCLADILTDNTHSEATHAEAAAVIAQITSPHLTFTQHLSSFLENMEEIVTALVKLCQEASSGEVFLLASAALANITFFDTMACEMLLQLNAMKILLAACSDKHIVDTPYSRDQVVTILANMSVLDQCASEIIQGNGVQLLMEMLFERSSSGNSAEVAACERVQQKSAVTLARLSRDPEVADAAVKLSCIPRLIKLCRSPTERNNSDSVLVACLAALRRLAVMSPEGLEDSDFQQLVKPRLVDSFLLCTNMEESFV", "length": 557, "header": "tr|A0A8V0ZY39-1|A0A8V0ZSK0_CHICK Computationally mapped isoform of INSC spindle orientation adaptor protein OS=Gallus gallus OX=9031 GN=INSC PE=4 SV=1 CANONICAL=A0A8V0ZSK0-1" }, "locus": { "chromosome": "5", "start_pos": 10349144, "end_pos": 10245693, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055855.1", "url": "https://www.ensembl.org/id/ENSGALT00010055855.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033814.1", "url": "https://www.ensembl.org/id/ENSGALP00010033814.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0AAA9RS94-1", "protein_name": "Protein inscuteable homolog", "gene_name": "INSC", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MLEMWFDPWVGKIPWSRNWQPTPVFLPGKFHGQRNLGPDRCRQALLRIGVNMMALPGGRHLDSIPLPGQRPHLMQVDSVQRWMEDLKLMTECECMCVLQAKPISLEEDAQGDLILAGGPGPGDPLQLLLKRGWVISTELRRIGQKLAQDRWARVHSMSVRLTCHARSMVSEYSAVSRNSSQEMSQIEKLLMEKCSELSVVTERCLQVENEHVLKSMKACVSETLSTLGEHFGQLLELALTREVQALVRKIDASDNIYTTESTTGNLFSLTQEGAPLCRIIAKEGGVVALFKICRQDTLRCLYPQALRTLASICCVEEGVHQLEKVDGVLCLADILTDDSHSEATRAEAAAVVAQVTSPHLPFTQHLSSFLESMEEIVTALVKLCQEASSGEVFLLASAALANITFFDTMACEMLLQLNAIRVLLEACSDKQRVDTPYTRDQIVTILANMSVLEQCASDIIQENGVQLIMGMLSEKPRSGTPAEVAACERVQQKAAVTLARLSRDPDVAREAVRLSCMSRLIELCRSPSERNSSDAVLVACLAALRRLAGVCPEGLQDSDFQQLVQPRLVDSFLLCSNMEESFV", "length": 583 }, "evidence": [ { "id": "A0A8V0ZSK0", "url": "https://omabrowser.org/oma/group/A0A8V0ZSK0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "D3ZFP7-1", "protein_name": "Protein inscuteable homolog", "gene_name": "Insc", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRRPPGDGDSTGEGPGNWGLWGAQESRRLCCVGPDRCGQALLQIGMNMMALPGGRHLGSIPLQEQRLHFMQVDSVQRWMEDLKLMTECECMCVLQAKPISLEEDTQSDLILAGGPGPGDPLQLLLKRGWVISTELRRIGQKLAQDRWARVHSMSVRLTCHARSMVSEYSTISRTTSQEMGQAEKLLMEKCSELSAVTERCLQVENEHVLKSMKACVSETLSMLGQHFGQLLELALTREVQALVRKIDTSDNIYITESTTGNLFSLTQEGAPLCRIIAKEGGVVALFKVCRQDTFRCLYPQALRTLASICCVEEGVHQLEKVDGILCLTDILTDDSHSEATRAEAAAVVAQVTSPHLSFTQHLTSFLENMEEIVTALIKLCQEASSGEVFLLASAALANITFFEKMACEMLLQLNAIRVLLEACGDKQRVDTPYTRDQIVTILANMSVLEQCASDIIQENGVQLIMGMLSEKPRSGTPAEVAACERVQQKAAVTLARLCRDPDVAREAVRLSCMSRLIELCRSPSERNSSDAVLVACLAALRRLAGVCPEGLQDSDFQQLVQPRLVDSFLLCSNMEESFV", "length": 579 }, "evidence": [ { "id": "A0A8V0ZSK0", "url": "https://omabrowser.org/oma/group/A0A8V0ZSK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q1MX18-1", "protein_name": "Protein inscuteable homolog", "gene_name": "INSC", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRRPPGNGEAASEGPGGWGLWGVQESRRLCCAGHDRCKQALLQIGINMMALPGGRHLDSVTLPGQRLHLMQVDSVQRWMEDLKLMTECECMCVLQAKPISLEEDAQGDLILAGGPGPGDPLQLLLKRGWVISTELRRIGQKLAQDRWARVHSMSVRLTCHARSMVSEYSAVSRNSLKEMGEIEKLLMEKCSELSAVTERCLQVENEHVLKSMKACVSETLSMLGQHFGQLLELALTREVQALVRKIDASDNIYTTESTTGNLFSLTQEGAPLCRIIAKEGGVVALFKVCRQDSFRCLYPQALRTLASICCVEEGVHQLEKVDGVLCLADILTDNSHSEATRAEAAAVVAQVTSPHLPVTQHLSSFLESMEEIVTALVKLCQEASSGEVFLLASAALANITFFDTMACEMLLQLNAIRVLLEACSDKQRVDTPYTRDQIVTILANMSVLEQCASDIIQENGVQLIMGMLSEKPRSGTPAEVAACERVQQKAAVTLARLSRDPDVAREAVRLSCMSRLIELCRSPSERNSSDAVLVACLAALRRLAGVCPEGLQDSDFQQLVQPRLVDSFLLCSNMEESFV", "length": 579 }, "evidence": [ { "id": "A0A8V0ZSK0", "url": "https://omabrowser.org/oma/group/A0A8V0ZSK0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q3HNM7-1", "protein_name": "Protein inscuteable homolog", "gene_name": "Insc", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRRPPGDGDSTGEGPGNWGLWGAQESRRLCCVGPDRCGQALLQIGINMMALPGGRHLDSVPLQEQRLHFMQVDSVQRWMEDLKLMTECECMCVLQAKPISLEEDTQGDLILAGGPGPGDPLQLLLKRGWVISTELRRIGQKLAQDRWARVHSMSVRLTCHARSMVSEYSTISRTASQEMGQAEKLLMEKCSELSAVTERCLQVENEHVLKSMKACVSETLSLLGEHFGQLLELALTREVQALVRKIDTSDNIYITESTTGNLFGLTQEGAPLCRIIAKEGGVVALFKVCRQDSFRCLYPQALRTLASICCVEEGVHQLEKVDGILCLADILTDESHSEATRAEAAAVVAQVTSPHLSFTQHLTSFLENMEEIVTALIKLCQEASSGEVFLLASAALANITFFDKMACEMLLQLNAIRVLLEACGDKQRVDTPYTRDQIVTILANMSVLEQCGSDIIQENGVQLIMGMLSEKPRSGTPAEVAACERVQQKAAVTLARLCRDPDVAQEAVRLSCMSRLIELCRSPSERNSSDAVLVACLAALRRLAGVCPEGLQDSDFQQLVQPRLVDSFLLCSNMEESFV", "length": 579 }, "evidence": [ { "id": "A0A8V0ZSK0", "url": "https://omabrowser.org/oma/group/A0A8V0ZSK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "regulation of asymmetric cell division", "id": "GO:0009786", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009786", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSK0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSK0" } ], "pmid": "" }, { "name": "regulation of protein stability", "id": "GO:0031647", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031647", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSK0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSK0" } ], "pmid": "" }, { "name": "asymmetric cell division", "id": "GO:0008356", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008356", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSK0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSK0" } ], "pmid": "" }, { "name": "apical protein localization", "id": "GO:0045176", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045176", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSK0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSK0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "apical cortex", "id": "GO:0045179", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045179", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSK0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSK0" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSK0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSK0" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSK0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSK0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein domain specific binding", "id": "GO:0019904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019904", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSK0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSK0" } ], "pmid": "" }, { "name": "cytoskeletal anchor activity", "id": "GO:0008093", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008093", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSK0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSK0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 207, "end_pos": 209, "annotation": "n_glycosylation_sequon" }, { "start_pos": 388, "end_pos": 390, "annotation": "n_glycosylation_sequon" }, { "start_pos": 434, "end_pos": 436, "annotation": "n_glycosylation_sequon" }, { "start_pos": 517, "end_pos": 519, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZSK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSK0" }, { "id": "PF19427", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19427" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Protein inscuteable homologue C-terminal", "eco_id": "ECO_0000259", "start_pos": 117, "end_pos": 569, "start_aa": "Arg", "end_aa": "Val", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZSK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSK0" }, { "id": "PF16748", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16748" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Protein inscuteable homologue LGN-binding", "eco_id": "ECO_0000259", "start_pos": 60, "end_pos": 104, "start_aa": "Ile", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 207, "end_pos": 209 }, { "start_pos": 388, "end_pos": 390 }, { "start_pos": 434, "end_pos": 436 }, { "start_pos": 517, "end_pos": 519 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": 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factor related to kappa-B-binding protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001185485" }, "gene_names": [ { "name": "NFRKB", "type": "recommended", "evidence": [ { "id": "A0A8V0ZSK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSK7" } ] }, { "name": "NFRKB", "type": "synonym", "evidence": [ { "id": "NP_001185485", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001185485" } ] } ], "protein_names": [ { "name": "Nuclear factor related to kappa-B-binding protein", "type": "recommended", "evidence": [ { "id": "A0A8V0ZSK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSK7/entry#names_and_taxonomy" } ] }, { "name": "DNA-binding protein R kappa-B", "type": "synonym", "evidence": [ { "id": "A0A8V0ZSK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSK7/entry#names_and_taxonomy" } ] }, { "name": "nuclear factor related to kappa B binding protein", "type": "synonym", "evidence": [ { "id": "NP_001185485", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001185485" } ] }, { "name": "nuclear factor related to kappa-B-binding protein", "type": "synonym", "evidence": [ { "id": "NP_001185485", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001185485" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000341.1. On Sep 23, 2021 this sequence version replaced NP_001185485.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments of chick cDNAs and human NFRKB NP_006156.2.", "evidence": [ { "database": "RefSeq", "id": "NP_001185485", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001185485" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSK7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSK7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NFRKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSK7", "locus": { "chromosome": "24", "start_pos": 1610924, "end_pos": 1593609, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010023289", "url": "https://www.ensembl.org/id/ENSGALG00010023289" } ] } } ], "crossref": [ { "id": "cd21865", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21865", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "419730", "url": "https://www.ncbi.nlm.nih.gov/gene/419730", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR024867", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024867", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025220", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025220", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038106", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038106", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044867", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044867", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057748", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057748", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:419730", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419730", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RVSWTDF", "url": "https://omabrowser.org/oma/group/RVSWTDF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZMC4", "url": "https://www.orthodb.org/?gene=A0A8V0ZMC4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZSK7", "url": "https://www.orthodb.org/?gene=A0A8V0ZSK7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZVS9", "url": "https://www.orthodb.org/?gene=A0A8V0ZVS9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13052", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13052", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13052:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13052:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14465", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14465", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25793", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25793", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-5689603", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5689603", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5696394", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5696394", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001185485", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001185485", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMC4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMC4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMC4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMC4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZSK7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSK7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZSK7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSK7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZVS9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVS9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZVS9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVS9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDSLDHMLTDPLELGPCGDGNGARIMEDCLLGTTRVSLPEDLLEDPEIFFEVVSLSTWQEVLTDAQQEHLKTFLPHFPENNREHQNKIISALFSGENFRFGNPLHIAQKLFRDGHFNPEVVKYRQLCLKSQYKRYLSSQQQYFYRLLKQILASRNHLLELARKGGPDMILKRKHFSPSYDAEEREKRTHRRYLKILREVKEECGDTTLSSDEEDLSSWPPSSPSRCPSPPIPLRVIPTLSTMDMKTADRIELGESDLKMMLRKHREKRKYQPDHPDLVTADITLEDVMTRVNAGRKGSLAALFDLATFKKKVKEKDDKKKKKLKIIKSEVEDLTDSFSSAHGIPSLSQDHSPIPLSSVKEEPLEEMKPCLGINEISSSFFFLLLEILFLEGPASLSVLEDKVIDWQTSPASALNTWFSFAPNWSELVLPALQYLTGDSRDVPSSFSPFVEFKEKTQQWKLLGSCQDHEKELAALFQLWLETKDQTFFKENEDSSDATTPIPRVRTDYVVRPSTGEEKRVFQEQERYRYSQPHKAFTFRMHGFESVVGPVKGVFDKETSLNKAREHSLLRSDRPAYVTILSLVRDAAARLPNGEGTRAEICELLKDSQFLAPDVTSAQVNTVVSGALDRLHYEKDPCVKYDIGRKLWIYLHRDRSEEEFERIHQAQAAAAKAKKALQQKPKPPAKVKSSNKESSVKALPSSTSEPSQLSLSDSSMPPTPVTPVTPTAPALPATPISPPPVSVVSKSVPSAGSEPAKPSQSVLLVSSPTMPQLGTLLSTAQSSQTQPGPQPPPTRVVSHTASSVLPQVRVVSAQSSLPAVSQQAPVVTQQQQQPTSVPQIRVPATATQTKVLPQAVMTLPVKAQTSPVQVQRQGTSVTGQTGITVTGLSAAPSPAVKAVTSSPGSSATSTSSTTVIQNVAGQNIIKQVAITGQLGMKTQPGSSIPLTATNFRIQGKDVLRLPPSSITTDAKGQTVLRITPDMMATLAKSQVTTVKLTQDLFTAAAGSSASGKGISATLHVTSNPVQTADSPAKTSTASSSSSPAGSTVVKVTPDLKTTEPTSSAFRLMPALGMTVADQKSKAITTVASTEAKPAATIRIVQGLGVMPPKAGQTITVATHAKQVPSSAAVSVPGTVHTSAVSLPTMSATVSKAVAVASGAAGTPITIGTGGTAVRQVPVSTTVVSTSQAGKLPARITVPLSVISQPVKGKSVVTAPIIKGNLGANISGLGRNIILTTMPAGTKLIAGNKPVSFLTAQQLQQLQQQGQATQVRIQTVPASHLQQGTVSGSAKAVSTVVVTTAPSPKQSQDQL", "length": 1308, "header": "tr|A0A8V0ZSK7-1|A0A8V0ZSK7_CHICK Isoform 1 of Nuclear factor related to kappa-B-binding protein OS=Gallus gallus OX=9031 GN=NFRKB PE=3 SV=1 CANONICAL=A0A8V0ZSK7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZMC4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSK7/entry#A0A8V0ZMC4-1", "sequence": { "sequence": "MDSLDHMLTDPLELGPCGDGNGARIMEDCLLGTTRVSLPEDLLEDPEIFFEVVSLSTWQEVLTDAQQEHLKTFLPHFPENNREHQNKIISALFSGENFRFGNPLHIAQKLFRDGHFNPEVVKYRQLCLKSQYKRYLSSQQQYFYRLLKQILASRNHLLELARKGGPDMILKRKHFSPSYDAEEREKRTHRRYLKILREVKEECGDTTLSSDEEDLSSWPPSSPSRCPSPPIPLRVIPTLSTMDMKTADRIELGESDLKMMLRKHREKRKYQPDHPDLVTADITLEDVMTRVNAGRKGSLAALFDLATFKKKVKEKDDKKKKKLKIIKSEVEDLTDSFSSAHGIPSLSQDHSPIPLSSVKEEPLEEMKPCLGINEISSSFFFLLLEILFLEGPASLSVLEDKVIDWQTSPASALNTWFSFAPNWSELVLPALQYLTGDSRDVPSSFSPFVEFKEKTQQWKLLGSCQDHEKELAALFQLWLETKDQTFFKENEDSSDATTPIPRVRTDYVVRPSTGEEKRVFQEQERYRYSQPHKAFTFRMHGFESVVGPVKGVFDKETSLNKAREHSLLRSDRPAYVTILSLVRDAAARLPNGEGTRAEICELLKDSQFLAPDVTSAQVNTVVSGALDRLHYEKDPCVKYDIGRKLWIYLHRDRSEEEFERIHQAQAAAAKAKKALQQKPKPPAKVKSSNKESSVKALPSSTSEPSQLSLSDSSMPPTPVTPVTPTAPALPATPISPPPVSVVSKSVPSAGSEPAKPSQSVLLVSSPTMPQLGTLLSTAQSSQTQPGPQPPPTRVVSHTASSVLPQVRVVSAQSSLPAVSQQAPVVTQQQQQPTSVPQIRVPATATQTKVLPQVAITGQLGMKTQPGSSIPLTATNFRIQGKDVLRLPPSSITTDAKGQTVLRITPDMMATLAKSQVTTVKLTQDLFTAAAGSSASGKGISATLHVTSNPVQTADSPAKTSTASSSSSPAGSTVVKVTPDLKTTEPTSSAFRLMPALGMTVADQKSKAITTVASTEAKPAATIRIVQGLGVMPPKAGQTITVATHAKQVPSSAAVSVPGTVHTSAVSLPTMSATVSKAVAVASGAAGTPITIGTGGTAVRQVPVSTTVVSTSQAGKLPARITVPLSVISQPVKGKSVVTAPIIKGNLGANISGLGRNIILTTMPAGTKLIAGNKPVSFLTAQQLQQLQQQGQATQVRIQTVPASHLQQGTVSGSAKAVSTVVVTTAPSPKQSQDQL", "length": 1235, "header": "tr|A0A8V0ZMC4-1|A0A8V0ZMC4_CHICK Computationally mapped isoform of Nuclear factor related to kappa-B-binding protein OS=Gallus gallus OX=9031 GN=NFRKB PE=3 SV=1 CANONICAL=A0A8V0ZSK7-1" }, "locus": { "chromosome": "24", "start_pos": 1609677, "end_pos": 1594625, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056811.1", "url": "https://www.ensembl.org/id/ENSGALT00010056811.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034539.1", "url": "https://www.ensembl.org/id/ENSGALP00010034539.1" } ] } }, { "isoform_ac": "A0A8V0ZSK7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSK7/entry#A0A8V0ZSK7-1", "sequence": { "sequence": "MDSLDHMLTDPLELGPCGDGNGARIMEDCLLGTTRVSLPEDLLEDPEIFFEVVSLSTWQEVLTDAQQEHLKTFLPHFPENNREHQNKIISALFSGENFRFGNPLHIAQKLFRDGHFNPEVVKYRQLCLKSQYKRYLSSQQQYFYRLLKQILASRNHLLELARKGGPDMILKRKHFSPSYDAEEREKRTHRRYLKILREVKEECGDTTLSSDEEDLSSWPPSSPSRCPSPPIPLRVIPTLSTMDMKTADRIELGESDLKMMLRKHREKRKYQPDHPDLVTADITLEDVMTRVNAGRKGSLAALFDLATFKKKVKEKDDKKKKKLKIIKSEVEDLTDSFSSAHGIPSLSQDHSPIPLSSVKEEPLEEMKPCLGINEISSSFFFLLLEILFLEGPASLSVLEDKVIDWQTSPASALNTWFSFAPNWSELVLPALQYLTGDSRDVPSSFSPFVEFKEKTQQWKLLGSCQDHEKELAALFQLWLETKDQTFFKENEDSSDATTPIPRVRTDYVVRPSTGEEKRVFQEQERYRYSQPHKAFTFRMHGFESVVGPVKGVFDKETSLNKAREHSLLRSDRPAYVTILSLVRDAAARLPNGEGTRAEICELLKDSQFLAPDVTSAQVNTVVSGALDRLHYEKDPCVKYDIGRKLWIYLHRDRSEEEFERIHQAQAAAAKAKKALQQKPKPPAKVKSSNKESSVKALPSSTSEPSQLSLSDSSMPPTPVTPVTPTAPALPATPISPPPVSVVSKSVPSAGSEPAKPSQSVLLVSSPTMPQLGTLLSTAQSSQTQPGPQPPPTRVVSHTASSVLPQVRVVSAQSSLPAVSQQAPVVTQQQQQPTSVPQIRVPATATQTKVLPQAVMTLPVKAQTSPVQVQRQGTSVTGQTGITVTGLSAAPSPAVKAVTSSPGSSATSTSSTTVIQNVAGQNIIKQVAITGQLGMKTQPGSSIPLTATNFRIQGKDVLRLPPSSITTDAKGQTVLRITPDMMATLAKSQVTTVKLTQDLFTAAAGSSASGKGISATLHVTSNPVQTADSPAKTSTASSSSSPAGSTVVKVTPDLKTTEPTSSAFRLMPALGMTVADQKSKAITTVASTEAKPAATIRIVQGLGVMPPKAGQTITVATHAKQVPSSAAVSVPGTVHTSAVSLPTMSATVSKAVAVASGAAGTPITIGTGGTAVRQVPVSTTVVSTSQAGKLPARITVPLSVISQPVKGKSVVTAPIIKGNLGANISGLGRNIILTTMPAGTKLIAGNKPVSFLTAQQLQQLQQQGQATQVRIQTVPASHLQQGTVSGSAKAVSTVVVTTAPSPKQSQDQL", "length": 1308, "header": "tr|A0A8V0ZSK7-1|A0A8V0ZSK7_CHICK Isoform 1 of Nuclear factor related to kappa-B-binding protein OS=Gallus gallus OX=9031 GN=NFRKB PE=3 SV=1 CANONICAL=A0A8V0ZSK7-1" }, "locus": { "chromosome": "24", "start_pos": 1609677, "end_pos": 1594625, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056806.1", "url": "https://www.ensembl.org/id/ENSGALT00010056806.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034536.1", "url": "https://www.ensembl.org/id/ENSGALP00010034536.1" } ] } }, { "isoform_ac": "A0A8V0ZVS9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSK7/entry#A0A8V0ZVS9-1", "sequence": { "sequence": "MDSLDHMLTDPLELGPCGDGNGARIMEDCLLGTTRVSLPEDLLEDPEIFFEVVSLSTWQEVLTDAQQEHLKTFLPHFPENNREHQNKIISALFSGENFRFGNPLHIAQKLFRDGHFNPEVVKYRQLCLKSQYKRYLSSQQQYFYRLLKQILASRNHLLELARKGGPDMILKRKHFSPSYDAEEREKRTHRRYLKILREVKEECGDTTLSSDEEDLSSWPPSSPSRCPSPPIPLRVIPTLSTMDMKTADRIELGESDLKMMLRKHREKRKYQPDHPDLVTADITLEDVMTRVNAGRKGSLAALFDLATFKKKVKEKDDKKKKKLKIIKSEVEDLTDSFSSAHGIPSLSQDHSPIPLSSVKEEPLEEMKPCLGINEISSSFFFLLLEILFLEGPASLSVLEDKVIDWQTSPASALNTWFSFAPNWSELVLPALQYLTGDSRDVPSSFSPFVEFKEKTQQWKLLGSCQDHEKELAALFQLWLETKDQTFFKENEDSSDATTPIPRVTDYVVRPSTGEEKRVFQEQNRRELCFTSFLRENGKWRGELTRLVEAEARITGKQRVVV", "length": 561, "header": "tr|A0A8V0ZVS9-1|A0A8V0ZSK7_CHICK Computationally mapped isoform of Nuclear factor related to kappa-B-binding protein OS=Gallus gallus OX=9031 GN=NFRKB PE=3 SV=1 CANONICAL=A0A8V0ZSK7-1" }, "locus": { "chromosome": "24", "start_pos": 1602866, "end_pos": 1594625, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056798.1", "url": "https://www.ensembl.org/id/ENSGALT00010056798.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034532.1", "url": "https://www.ensembl.org/id/ENSGALP00010034532.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 720, "start_aa": "Thr", "end_pos": 720, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr720", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 725, "start_aa": "Thr", "end_pos": 725, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr725", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:419730", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419730", "resource": "KEGG Pathway" }, { "id": "R-GGA-5689603", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5689603", "resource": "Reactome", "description": "UCH proteinases" }, { "id": "R-GGA-5696394", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5696394", "resource": "Reactome", "description": "DNA Damage Recognition in GG-NER" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8M2B866-1", "protein_name": "Nuclear factor related to kappa-B-binding protein", "gene_name": "nfrkb", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDALDHMLTDPLESAMDQDGRVMEECMLGNCRVRVPEDLLEDPEIFFSVLSESTWTDVLTEAQRTHLRQLLPQFPEENMAEQNSIIGDLFNNKNFLFGNPLHIAQKLFRDGHFNPEVVKYRQLCAKSQKKRQIYSLQQYYHKLLKQILVSRKELLDLAVRSGPELAVKRRYPAASHKEMLEQRVRRRVGHIIKDVKTECGDSNVSSDEDDSSSWLPVPQSPSSPTPTFSLRVLPSLSTQDMKTRDKPELGEKELRAMLHRHREKRKRQPDHPDLMTSDLHLGDIMSRVNIGRKGSVTVFDLAIPKKKIKEEKRKKKMRPIKMESEEVCDVQMSAPPMNPGLTDVPAAPPQSVKEEPIDEPQTSPDTVEEIAMSFFHLLEDILRLEGLATSSTMEEKVQQWQSSPASTLNPWFSMAPCWSEVVVPALQFLAGESKAGVMALPTGFIPFVEFKEVSQQWKWIGSSQDGDKDLSALCQLWLESKDHVIVKQEGEETAELTPPTPRVWTDYVVRPSTGEERHVFQEQEQQRYDQPHKAFTYRMHGFESVVGPVKGVFDKETSLNKAREHSLLRSDRPAYVTILSLVRDAAARLPNGEGTRAEICELLKDSQFLAPDVTSAQVNTVVSGALDRLHYEKDPCVKYDIGRKLWIYLHRDRSQEEFERIHQAQAAAAKAKKALQQKPKPAPKPKAGGKEPGSKNGIAEAGQSTSNEGIAIAATSLSQTPSTPTQSTPGTPKSPLPPTSATPTKVAAPEPIKTNPSVLLVSPPTMPQLGTLLSASQPSPQVSQQASPQSATRVVAHSAATGSLPQVRVVTAQPSLHTSTAGQAATLVHQSPHHIRVPVTVAHGKNITQAVVTLPLRNQSAGSPIQVQASRGQASLTVPGLASAVTVTKPQTSSPASPAHNQTAPAVLQGVSSQSIIKQVAITGQLGVKTQSGAGIPLTATNLRIQGKDVLRLPPSSITTDAKGQTVLRITPDMMATLTKSPVATVKLTPDMLSSATSSGSKSISATLHVSQPQPSPPTSSTTASENLAVKTPATLVKVHPELKTACDTAIRLMPALAVTMADSKARTFSTVTSSDSKAGTTIRIVPNLGVIPQKQGQAVSIATTTTSTKPITVSSGAATVTIATSGVAGAKGVTLGTAGTGSTLSLGTAAATVRQVPVSATVVTTQTGKLPTRITVPLSVLSQPLKNKSVVTTPILKGNISTNISNLGRNIILTTMPAGTKLIAGNKPVSFVTAQQLQQLQQQGQATQVRIQTVPAQQLQRTAASSPKSTVSTVVVSTAPSPKTNPDPQ", "length": 1290 }, "evidence": [ { "id": "A0A8V0ZSK7", "url": "https://omabrowser.org/oma/group/A0A8V0ZSK7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1MPR9-1", "protein_name": "Nuclear factor related to kappa-B-binding protein", "gene_name": "NFRKB", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MDSLDHMLTDPLELGPCGDGQGSRIMEDCLLGGTRVSLPEDLLEDPEIFFDVVSLSTWQEVLSDSQREHLQQFLPLFPEDSMEQQNQLILALFSGENFRFGNPLHIAQKLFRDGHFNPEVVKYRQLCFRSQYKRYLSSQQQYFHRLLKQILASRSDLLEMARRSGPAFPSRQKRPWPSRAPEEREWRTQQRYLKVLREVKEECGDTALSSDEEDLSSWLPSSPARSPSPAVPLRVVPTLSTTDMKTADKIELGDSDLKIMLKKHHEKRKYQPDHPDLLTGDLTLNDIMTRVNAGRKGSLAALYDLAVLKKKVKEKEERKKKKIKLIKSEVEDLAEPLSGPEGLPPLSQAPSPLAIPAIKEEPLEDLKPCLGINEISSSFFSLLLEILLLEGQASLPLLEERVLDWQSSPASSLNSWFSAAPNWAELVLPALQYLAGESRAVPSSFSPFVEFKEKTQHWKLLGQSQDNEKELAALFQLWLETKDQAFCKQETEDSSDATTPVPRVRTDYVVRPSTGEEKRVFQEQERYRYSQPHKAFTFRMHGFESVVGPVKGVFDKETSLNKAREHSLLRSDRPAYVTILSLVRDAAARLPNGEGTRAEICELLKDSQFLAPDVTSTQVNTVVSGALDRLHYEKDPCVKYDIGRKLWIYLHRDRSEEEFERIHQAQAAAAKARKALQQKPKPPSKVKSSSKDGPVKVLSGGPSEQSQLSLSDSSMPPTPVTPVTPTTPALPATPISPPPVPPVNKNGPTTVSEPAKSTSGVLLVSSPTMPQLGTMLSPASSQTPPSSQAAARVVSHSGSAGLPQVRVVAPPSLPAVTQPAGPAPPLPPMPAGTQIRMPATGAQAKGGPQTVMATVPVKAQTATATVQRPGPGSAGLTVTSLPAAAKPTSKPATSSPGGPTPSTPTAAVLQSVAGQNIIKQVAITGQLGVKPQTGSSVPLTATNFRIQGKDVLRLPPSSITTDAKGQTVLRITPDMMATLAKSQVTTVKLTQDLFGTGAGTTGKGISATLHVTSNPVHATDSPAKAGVATAPSSTPTGTTVVKVTPDLKPARLMPALGVSVADQKGKNTVASSEAKPAATIRIVQGLGVMPPTAGQTITVAAHTKQGPSVAGGSGTVHTSAVSMPSVNAAVSKTVAVASGAASAPISIGTGAPAVRQVPVSTAVVSTSQAGKLPTRITVPLSVISQPMKGKSVVTAPIIKGNLGANLGGLGRNIILTTMPAGAKLIAGNKPVSFLTAQQLQQLQQQGQATQVRIQTVPASHLQQGTASGSSKAVSTVVVTTAPSPKQAPEQQ", "length": 1291 }, "evidence": [ { "id": "A0A8V0ZSK7", "url": "https://omabrowser.org/oma/group/A0A8V0ZSK7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q6P4R8-1", "protein_name": "Nuclear factor related to kappa-B-binding protein", "gene_name": "NFRKB", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDSLDHMLTDPLELGPCGDGHGTRIMEDCLLGGTRVSLPEDLLEDPEIFFDVVSLSTWQEVLSDSQREHLQQFLPQFPEDSAEQQNELILALFSGENFRFGNPLHIAQKLFRDGHFNPEVVKYRQLCFKSQYKRYLNSQQQYFHRLLKQILASRSDLLEMARRSGPALPFRQKRPSPSRTPEEREWRTQQRYLKVLREVKEECGDTALSSDEEDLSSWLPSSPARSPSPAVPLRVVPTLSTTDMKTADKVELGDSDLKIMLKKHHEKRKHQPDHPDLLTGDLTLNDIMTRVNAGRKGSLAALYDLAVLKKKVKEKEEKKKKKIKTIKSEAEDLAEPLSSTEGVAPLSQAPSPLAIPAIKEEPLEDLKPCLGINEISSSFFSLLLEILLLESQASLPMLEERVLDWQSSPASSLNSWFSAAPNWAELVLPALQYLAGESRAVPSSFSPFVEFKEKTQQWKLLGQSQDNEKELAALFQLWLETKDQAFCKQENEDSSDATTPVPRVRTDYVVRPSTGEEKRVFQEQERYRYSQPHKAFTFRMHGFESVVGPVKGVFDKETSLNKAREHSLLRSDRPAYVTILSLVRDAAARLPNGEGTRAEICELLKDSQFLAPDVTSTQVNTVVSGALDRLHYEKDPCVKYDIGRKLWIYLHRDRSEEEFERIHQAQAAAAKARKALQQKPKPPSKVKSSSKESSIKVLSSGPSEQSQMSLSDSSMPPTPVTPVTPTTPALPAIPISPPPVSAVNKSGPSTVSEPAKSSSGVLLVSSPTMPHLGTMLSPASSQTAPSSQAAARVVSHSGSAGLSQVRVVAQPSLPAVPQQSGGPAQTLPQMPAGPQIRVPATATQTKVVPQTVMATVPVKAQTTAATVQRPGPGQTGLTVTSLPATASPVSKPATSSPGTSAPSASTAAVIQNVTGQNIIKQVAITGQLGVKPQTGNSIPLTATNFRIQGKDVLRLPPSSITTDAKGQTVLRITPDMMATLAKSQVTTVKLTQDLFGTGGNTTGKGISATLHVTSNPVHAADSPAKASSASAPSSTPTGTTVVKVTPDLKPTEASSSAFRLMPALGVSVADQKGKSTVASSEAKPAATIRIVQGLGVMPPKAGQTITVATHAKQGASVASGSGTVHTSAVSLPSMNAAVSKTVAVASGAASTPISISTGAPTVRQVPVSTTVVSTSQAGKLPTRITVPLSVISQPMKGKSVVTAPIIKGNLGANLSGLGRNIILTTMPAGTKLIAGNKPVSFLTAQQLQQLQQQGQATQVRIQTVPASHLQQGTASGSSKAVSTVVVTTAPSPKQAPEQQ", "length": 1299 }, "evidence": [ { "id": "A0A8V0ZSK7", "url": "https://omabrowser.org/oma/group/A0A8V0ZSK7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 12, "go_terms": [ { "name": "regulation of DNA strand elongation", "id": "GO:0060382", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060382", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSK7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSK7" } ], "pmid": "" }, { "name": "chromatin remodeling", "id": "GO:0006338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006338", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSK7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSK7" } ], "pmid": "" }, { "name": "telomere maintenance", "id": "GO:0000723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000723", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSK7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSK7" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSK7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSK7" } ], "pmid": "" }, { "name": "positive regulation of DNA repair", "id": "GO:0045739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045739", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSK7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSK7" } ], "pmid": "" }, { "name": "regulation of DNA replication", "id": "GO:0006275", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006275", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSK7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSK7" } ], "pmid": "" }, { "name": "regulation of cell cycle", "id": "GO:0051726", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051726", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSK7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSK7" } ], "pmid": "" }, { "name": "regulation of embryonic development", "id": "GO:0045995", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045995", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSK7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSK7" } ], "pmid": "" }, { "name": "positive regulation of telomere maintenance in response to DNA damage", "id": "GO:1904507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904507", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSK7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSK7" } ], "pmid": "" }, { "name": "regulation of chromosome organization", "id": "GO:0033044", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033044", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSK7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSK7" } ], "pmid": "" }, { "name": "positive regulation of macromolecule metabolic process", "id": "GO:0010604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010604", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSK7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSK7" } ], "pmid": "" }, { "name": "regulation of DNA metabolic process", "id": "GO:0051052", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051052", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSK7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSK7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protease binding", "id": "GO:0002020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSK7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSK7" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSK7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSK7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSK7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSK7" } ], "pmid": "" }, { "name": "Ino80 complex", "id": "GO:0031011", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031011", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSK7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSK7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1222, "end_pos": 1224, "annotation": "n_glycosylation_sequon" }, { "start_pos": 422, "end_pos": 424, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZSK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSK7" }, { "id": "PS51916", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51916" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DEUBAD", "eco_id": "ECO_0000259", "start_pos": 39, "end_pos": 156, "start_aa": "Pro", "end_aa": "His", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 720, 725 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1222, "end_pos": 1224 }, { "start_pos": 422, "end_pos": 424 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZSL1-1", "uniprot_ac": "A0A8V0ZSL1", "uniprot_id": "A0A8V0ZSL1_CHICK", "mass": { "chemical_mass": 32157.0, "monoisotopic_mass": 32157.0 }, "refseq": { "ac": "NP_001264266", "name": "phenazine biosynthesis-like domain-containing protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264266" }, "gene_names": [ { "name": "PBLD", "type": "recommended", "evidence": [ { "id": "A0A8V0ZSL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSL1" } ] }, { "name": "PBLD", "type": "synonym", "evidence": [ { "id": "NP_001264266", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264266" } ] } ], "protein_names": [ { "name": "Phenazine biosynthesis like protein domain containing", "type": "synonym", "evidence": [ { "id": "A0A8V0ZSL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSL1/entry#names_and_taxonomy" } ] }, { "name": "phenazine biosynthesis-like domain-containing protein", "type": "synonym", "evidence": [ { "id": "NP_001264266", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264266" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: BX934609.1, HAEL01005388.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000229.1. On Apr 3, 2013 this sequence version replaced XP_421566.1. Sequence Note: This RefSeq record was created from transcript data from different strains because no single transcript from the same strain was available for the full length of the gene. The extent of this transcript is supported by transcript alignments and orthologous data.", "evidence": [ { "database": "RefSeq", "id": "NP_001264266", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264266" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSL1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSL1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PBLD", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSL1", "locus": { "chromosome": "6", "start_pos": 11317415, "end_pos": 11333493, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022956", "url": "https://www.ensembl.org/id/ENSGALG00010022956" } ] } } ], "crossref": [ { "id": "A0A8V0ZSL1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZSL1", "database": "AlphaFoldDB", "categories": [] }, { "id": "423685", "url": "https://www.ncbi.nlm.nih.gov/gene/423685", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:423685", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423685", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DWALRWF", "url": "https://omabrowser.org/oma/group/DWALRWF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZQQ3", "url": "https://www.orthodb.org/?gene=A0A8V0ZQQ3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZSL1", "url": "https://www.orthodb.org/?gene=A0A8V0ZSL1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZY44", "url": "https://www.orthodb.org/?gene=A0A8V0ZY44", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13774", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13774", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13774:SF17", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13774:SF17", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02567", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02567", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001264266", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264266", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQQ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQQ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQQ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQQ3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZSL1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSL1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZSL1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSL1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZY44", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZY44", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZY44-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZY44-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQVPIFTVDAFTNRPFCGNPAAVCLLENDLDEDLHQKIATEMNLSETAFIRKLHPTDDFTKSSRFGLRWFTPANEVPLCGHATLASAAVLFHIKKNPNSVLTFVTLSGELKTRQEKDHIVLDLPLYSTDPQVLQEVEELIKAATGDMIVQDVRYSPDTKKLLVRLSDAYERSVLEELQVSAQRFLSAEKTGKVKGLILTLKGKSNGKEKGHDFYSRYFAPWYGVLEDPVTGSAHAVLSSYWSEQLGKKEMLAFQCSRRGGELKISLHDNGRVEIAGQFAIVLKGNLTL", "length": 288, "header": "tr|A0A8V0ZSL1-1|A0A8V0ZSL1_CHICK Isoform 1 of Phenazine biosynthesis like protein domain containing OS=Gallus gallus OX=9031 GN=PBLD PE=1 SV=1 CANONICAL=A0A8V0ZSL1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZQQ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSL1/entry#A0A8V0ZQQ3-1", "sequence": { "sequence": "MASRPRGYRDSSATRLGPPRQQRSMRVSGNKGQQRMRGSRFGLRWFTPANEVPLCGHATLASAAVLFHIKKNPNSVLTFVTLSGELKTRQEKDHIVLDLPLYSTDPQVLQEVEELIKAATGDMIVQDVRYSPDTKKLLVRLSDAYERSVLEELQVSAQRFLSAEKTGKVKGLILTLKGKSNGKEKGHDFYSRYFAPWYGVLEDPVTGSAHAVLSSYWSEQLGKKEMLAFQCSRRGGELKISLHDNGRVEIAGQFAIVLKGNLTL", "length": 264, "header": "tr|A0A8V0ZQQ3-1|A0A8V0ZQQ3_CHICK Computationally mapped isoform of Phenazine biosynthesis like protein domain containing OS=Gallus gallus OX=9031 GN=PBLD PE=1 SV=1 CANONICAL=A0A8V0ZSL1-1" }, "locus": { "chromosome": "6", "start_pos": 11333289, "end_pos": 11320338, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055875.1", "url": "https://www.ensembl.org/id/ENSGALT00010055875.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033825.1", "url": "https://www.ensembl.org/id/ENSGALP00010033825.1" } ] } }, { "isoform_ac": "A0A8V0ZSL1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSL1/entry#A0A8V0ZSL1-1", "sequence": { "sequence": "MQVPIFTVDAFTNRPFCGNPAAVCLLENDLDEDLHQKIATEMNLSETAFIRKLHPTDDFTKSSRFGLRWFTPANEVPLCGHATLASAAVLFHIKKNPNSVLTFVTLSGELKTRQEKDHIVLDLPLYSTDPQVLQEVEELIKAATGDMIVQDVRYSPDTKKLLVRLSDAYERSVLEELQVSAQRFLSAEKTGKVKGLILTLKGKSNGKEKGHDFYSRYFAPWYGVLEDPVTGSAHAVLSSYWSEQLGKKEMLAFQCSRRGGELKISLHDNGRVEIAGQFAIVLKGNLTL", "length": 288, "header": "tr|A0A8V0ZSL1-1|A0A8V0ZSL1_CHICK Isoform 1 of Phenazine biosynthesis like protein domain containing OS=Gallus gallus OX=9031 GN=PBLD PE=1 SV=1 CANONICAL=A0A8V0ZSL1-1" }, "locus": { "chromosome": "6", "start_pos": 11332713, "end_pos": 11320338, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055872.1", "url": "https://www.ensembl.org/id/ENSGALT00010055872.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033822.1", "url": "https://www.ensembl.org/id/ENSGALP00010033822.1" } ] } }, { "isoform_ac": "A0A8V0ZY44-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSL1/entry#A0A8V0ZY44-1", "sequence": { "sequence": "MQVPIFTVDAFTNRPFCGNPAAVCLLENDLDEDLHQKIATEMNLSETAFIRKLHPTDDFTKKNPNSVLTFVTLSGELKTRQEKDHIVLDLPLYSTDPQVLQEVEELIKAATGDMIVQDVRYSPDTKKLLVRLSDAYERSVLEELQVSAQRFLSAEKTGKVKGLILTLKGKSNGKEKGHDFYSRYFAPWYGVLEDPVTGSAHAVLSSYWSEQLGKKEMLAFQCSRRGGELKISLHDNGRVEIAGQFAIVLKGNLTL", "length": 255, "header": "tr|A0A8V0ZY44-1|A0A8V0ZSL1_CHICK Computationally mapped isoform of Phenazine biosynthesis like protein domain containing OS=Gallus gallus OX=9031 GN=PBLD PE=1 SV=1 CANONICAL=A0A8V0ZSL1-1" }, "locus": { "chromosome": "6", "start_pos": 11332713, "end_pos": 11320338, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055868.1", "url": "https://www.ensembl.org/id/ENSGALT00010055868.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033819.1", "url": "https://www.ensembl.org/id/ENSGALP00010033819.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:423685", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423685", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "P30039-1", "protein_name": "Phenazine biosynthesis-like domain-containing protein", "gene_name": "PBLD", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKLPIFIADAFTARAFRGNPAAVCLLENELDEDMHQKIAREMNLSETAFIRKLHPTDNFAQSSCFGLRWFTPASEVPLCGHATLASAAVLFHKIKNMNSTLTFVTLSGELRARRAEDGIVLDLPLYPAHPQDFHEVEDLIKTAIGNTLVQDICYSPDTQKLLVRLSDVYNRSFLENLKVNTENLLQVENTGKVKGLILTLKGEPGGQTQAFDFYSRYFAPWVGVAEDPVTGSAHAVLSSYWSQHLGKKEMHAFQCSHRGGELGISLRPDGRVDIRGGAAVVLEGTLTA", "length": 288 }, "evidence": [ { "id": "A0A8V0ZSL1", "url": "https://omabrowser.org/oma/group/A0A8V0ZSL1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q2HJF4-1", "protein_name": "Phenazine biosynthesis-like domain-containing protein", "gene_name": "PBLD", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MKLPIFIADAFTTKAFRGNPAAVCLLENKLDEDLHQKIAKEMNLSETAFIRKLHPNDNFTQSSCFGLRWFTPQNEVPLCGHATLASAAVLFHKIKNVHSTLTFVTMSGELKARKEEDGIVLDLPLYPAHPQKLHEVEDLIKTAIGDTLVQDVRYSPDTKKLLVRLSDTYNRSFLESLTVNTENLLQVETTGKVKGLILTLKGEPGGQTQAFDFYSRYFAPWYGVAEDPVTGSAHTVLSSYWSEQLGKKDLHAFQCSNRGGELTISLRSDGRVDIKGGAALVLEGTLTA", "length": 288 }, "evidence": [ { "id": "A0A8V0ZSL1", "url": "https://omabrowser.org/oma/group/A0A8V0ZSL1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q68G31-1", "protein_name": "Phenazine biosynthesis-like domain-containing protein", "gene_name": "Pbld", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKLPIFIADAFTVTAFHGNPAAVCLLESILQEDAHQQIAREMNLSETAFIRKLQPTDSFSQSSCFGLRWFTPVSEVPLCGHATMASAAVLFHKIKNVNSTLTFVTLSGELKARRAEDGIVLDFPLYPTFPQDFHEVKDLIKAAIGDTTVQDIQYSPDTRKLLVRLSDSYDRSFLESLKVNTEPLPGIEKTGKVKGLILTVKGESGGQTTPYDFYSRYFAPWVGVPEDPVTGSAHTVLSSYWSQQLGKKEMRAFQCSCRGGELDISLRPDGRVDMKGGAAVVLEGMLTA", "length": 288 }, "evidence": [ { "id": "A0A8V0ZSL1", "url": "https://omabrowser.org/oma/group/A0A8V0ZSL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9DCG6-1", "protein_name": "Phenazine biosynthesis-like domain-containing protein 1", "gene_name": "Pbld1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKLPIFIADAFTATAFRGNPAAVCLLERTLEEDAHQQIAREMNLSETAFIRKLQPTDSFTQSSRFGLRWFTPVSEVPLCGHATLASAAVLFHKIQNRNSTLTFVTMSGELKARRAEDGIVLDFPVYPTFPQDFHEVEDLIKAAIGDTLVQDIRYSTDTRKLLVRLSDSYDRSFLESLKVNTEPLPAIEKTGKVRGLILTVKGEPGGQTAPYDFYSRYFAPWVGIAEDPVTGSAHTVLSSYWSQQLRKKEMRAFQCSRRGGELDISLRPDGRVDIKGGAVIVLEGTLTA", "length": 288 }, "evidence": [ { "id": "A0A8V0ZSL1", "url": "https://omabrowser.org/oma/group/A0A8V0ZSL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9ZVS2-1", "protein_name": "Phenazine biosynthesis PhzC/PhzF protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAEKKRVKYFIVDAFAESAFKGNPAAVCFLEDDNERDDAWLQSLATEFNISETCFLTPIIGDLPRFRLRWFTPVAEVDLCGHATLASAHVLFSTGLVGSETVEFDTLSGILTAKHLKNDDDGEESSIELDFPVVPTYEVNYIDDDLSLFSKALNGATILDVKATKKDLLVVLSSWEAVIDLKPRLDEISKCPCEGMMVTAAASDGSTYDFCSRYFAPRFGINEDPVTGSAHCALAHYWSLRMNKCDFFAYQASSRGGTLKVHLDKEKQRVLLRGKAVTVMEGYVLV", "length": 286 }, "evidence": [ { "id": "A0A8V0ZSL1", "url": "https://omabrowser.org/oma/group/A0A8V0ZSL1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSL1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSL1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSL1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSL1" } ], "pmid": "" }, { "name": "isomerase activity", "id": "GO:0016853", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016853", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSL1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSL1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSL1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSL1" } ], "pmid": "" }, { "name": "maintenance of gastrointestinal epithelium", "id": "GO:0030277", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030277", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSL1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSL1" } ], "pmid": "" }, { "name": "positive regulation of canonical NF-kappaB signal transduction", "id": "GO:0043123", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043123", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSL1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSL1" } ], "pmid": "" }, { "name": "positive regulation of type I interferon production", "id": "GO:0032481", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032481", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSL1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSL1" } ], "pmid": "" }, { "name": "antiviral innate immune response", "id": "GO:0140374", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140374", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSL1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSL1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 285, "end_pos": 287, "annotation": "n_glycosylation_sequon" }, { "start_pos": 43, "end_pos": 45, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 285, "end_pos": 287 }, { "start_pos": 43, "end_pos": 45 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZSL5-1", "uniprot_ac": "A0A8V0ZSL5", "uniprot_id": "A0A8V0ZSL5_CHICK", "mass": { "chemical_mass": 19414.0, "monoisotopic_mass": 19414.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "ALX homeobox 3", "type": "synonym", "evidence": [ { "id": "A0A8V0ZSL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSL5/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSL5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSL5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSL5", "locus": {} } ], "crossref": [ { "id": "A0A8V0ZSL5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZSL5", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00086", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00086", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001356", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001356", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050649", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050649", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR24329", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24329", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24329:SF578", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24329:SF578", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZSL5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSL5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZSL5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSL5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "PESREHGPGAHPAGALPAGTGRGRGPQPSTPPPLCPQVWFQNRRAKWRKRERYGKIQEVRTPPLARPHSGVLAAFFQLQNNLWPSSGSPAGPSLVPPDSAPSPRVSPYPHAHSNIAGFVGIPASPGHPPGINSLYSLHSLTPPSLAAPHFEPPPSENDYKQPTLVTLRMTAKEPGSLLGWAT", "length": 182, "header": "tr|A0A8V0ZSL5-1|A0A8V0ZSL5_CHICK Isoform 1 of ALX homeobox 3 OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0ZSL5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZSL5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSL5/entry#A0A8V0ZSL5-1", "sequence": { "sequence": "PESREHGPGAHPAGALPAGTGRGRGPQPSTPPPLCPQVWFQNRRAKWRKRERYGKIQEVRTPPLARPHSGVLAAFFQLQNNLWPSSGSPAGPSLVPPDSAPSPRVSPYPHAHSNIAGFVGIPASPGHPPGINSLYSLHSLTPPSLAAPHFEPPPSENDYKQPTLVTLRMTAKEPGSLLGWAT", "length": 182, "header": "tr|A0A8V0ZSL5-1|A0A8V0ZSL5_CHICK Isoform 1 of ALX homeobox 3 OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0ZSL5-1" }, "locus": { "chromosome": "26", "start_pos": 1365781, "end_pos": 1364003, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010059714.1", "url": "https://www.ensembl.org/id/ENSGALT00010059714.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036479.1", "url": "https://www.ensembl.org/id/ENSGALP00010036479.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSL5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSL5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "sequence-specific double-stranded DNA binding", "id": "GO:1990837", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990837", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSL5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSL5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZSL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSL5" }, { "id": "PS50071", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50071" }, { "id": "PRU00108", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00108" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Homeobox", "eco_id": "ECO_0000259", "start_pos": 37, "end_pos": 50, "start_aa": "Gln", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZSL6-1", "uniprot_ac": "A0A8V0ZSL6", "uniprot_id": "A0A8V0ZSL6_CHICK", "mass": { "chemical_mass": 116484.0, "monoisotopic_mass": 116484.0 }, "refseq": { "ac": "XP_015134392", "name": "SAFB-like transcription modulator isoform X4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015134392" }, "gene_names": [ { "name": "SLTM", "type": "recommended", "evidence": [ { "id": "A0A8V0ZSL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSL6" } ] }, { "name": "SLTM", "type": "synonym", "evidence": [ { "id": "XP_015134392", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015134392" } ] } ], "protein_names": [ { "name": "SAFB-like transcription modulator", "type": "recommended", "evidence": [ { "id": "A0A8V0ZSL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSL6/entry#names_and_taxonomy" } ] }, { "name": "SAFB-like transcription modulator isoform X4", "type": "synonym", "evidence": [ { "id": "XP_015134392", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015134392" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052541.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015134392", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015134392" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSL6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSL6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SLTM", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSL6", "locus": { "chromosome": "10", "start_pos": 6916173, "end_pos": 6891765, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022957", "url": "https://www.ensembl.org/id/ENSGALG00010022957" } ] } } ], "crossref": [ { "id": "A0A8V0ZSL6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZSL6", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd12678", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12678", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "415401", "url": "https://www.ncbi.nlm.nih.gov/gene/415401", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003034", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003034", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036361", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036361", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051738", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051738", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZSL6", "url": "https://www.orthodb.org/?gene=A0A8V0ZSL6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZTI8", "url": "https://www.orthodb.org/?gene=A0A8V0ZTI8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15683", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15683", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15683:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15683:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00076", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00076", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02037", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02037", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015134392", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015134392", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZSL6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSL6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZSL6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSL6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZTI8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTI8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZTI8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTI8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAAASSPAAAGAPGAPTAPAAAAPPTTESKKISDLRVIDLKSELKRRNLDVTGVKTVLISRLKQAIEEEGGDPDNIEITVSADTPTKKPAKGKGKKQEADESTGDASVEDDSFVKESELETQDTSDQDGNDELKDFKESAEDENLNSKELPSAEKKRYLNVEPAETTEDVEKDSENQENEGQDMEDYTFPSVHDGEDEENEKDKAGSGDGTQEVSKPLPSEESLAEADHTAHEEMEANTSVKEAEDDNISVTIQAEDAITLDFDGDDLLETGKNVKITDSEASKPKDGQDAISQSLEKESKDYEMTENHKDGKKEDCVKGDPVKKEAREGSKKAESGDKEKDTLKKGPSSTGASGQAKSSTKESKESKTTSKDDKGGGSSVSGSSGSSTRNLWVSGLSSNTKAADLKNLFGKYGKVLGAKVVTNARSPGAKCYGIVTMSSSTEVARCIAHLHRTELHGQQISVEKVKGDPSKKELKKESDEKSSSSRSTGDKKTASSDKTSKTPSTKKEEKKSEKSEKKESKEGKKTEGKDEKSDNGTSGPNQESTKKTEEKKRISGKSPGHVVVLDQTKGDQGHSRTVRRGRFEKPQILRNKERIIQDKVKFREYRGRKDILPFEKMKEQRLREHMVRLERIRRAVELRRRREIAERERRERIRIMHEREECLQRERERLEIERQKLERERMERERLERERVRIEQERRKEAERIAREREELRRQQQQLRYEQEKRNALKRPRDVDHRRDDPYWNESKKMALDTDARFSHGSDYSRQPNRFNDFDHRERGRYPEGSVPSSSFDRRERFVNQGEAKKTRPTARREEPGFERYPKNFSDSRRNEPPPPRGELRDTDRREVRGDRDERRTVIIHDRPEIPHSRHPRETGSNPPRQTNWKNEGSISTDKRDGRGERPDRSGREVSGHVRGAPPGGRSSASGYGSREGERGVMGERGGGGQHYNEDRHVVERHSRETGPRKEWHGPSSQGSGYHDARRMGDGRGGSGMMSPHTSNSSPINRVVQITGNSMQRGSGSGFKPFKGGPPRRF", "length": 1036, "header": "tr|A0A8V0ZSL6-1|A0A8V0ZSL6_CHICK Isoform 1 of SAFB-like transcription modulator OS=Gallus gallus OX=9031 GN=SLTM PE=1 SV=1 CANONICAL=A0A8V0ZSL6-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZSL6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSL6/entry#A0A8V0ZSL6-1", "sequence": { "sequence": 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"length": 1036, "header": "tr|A0A8V0ZSL6-1|A0A8V0ZSL6_CHICK Isoform 1 of SAFB-like transcription modulator OS=Gallus gallus OX=9031 GN=SLTM PE=1 SV=1 CANONICAL=A0A8V0ZSL6-1" }, "locus": { "chromosome": "10", "start_pos": 6914682, "end_pos": 6891777, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055877.1", "url": "https://www.ensembl.org/id/ENSGALT00010055877.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033827.1", "url": "https://www.ensembl.org/id/ENSGALP00010033827.1" } ] } }, { "isoform_ac": "A0A8V0ZTI8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSL6/entry#A0A8V0ZTI8-1", "sequence": { "sequence": "MAAAASSPAAAGAPGAPTAPAAAAPPTTESKKISDLRVIDLKSELKRRNLDVTGVKTVLISRLKQAIEEEGGDPDNIEITVSADTPTKKPAKGKGKKQEADESTGDASVEDDSFVKESELETQDTSDQDGNDELKDFKESAEDENLNSKELPSAEKKRYLNVEPAETTEDVEKDSENQENEGQDMEDYTFPSVHDGEDEENEKDKAGSGDGTQEVSKPLPSEESLAEADHTAHEEMEANTSVKEAEDDNISVTIQAEDAITLDFDGDDLLETGKNVKITDSEASKPKDGQDAISQSLEKESKDYEMTENHKDGKKEDCVKGDPVKKEAREGSKKAESGDKEKDTLKKGPSSTGASGQAKSSTKESKESKTTSKDDKGGGSSVSGSSGSSTRNLWVSGLSSNTKAADLKNLFGKYGKVLGAKVVTNARSPGAKCYGIVTMSSSTEVARCIAHLHRTELHGQQISVEKVKGDPSKKELKKESDEKSSSSRSTGDKKTASSDKTSKTPSTKKEEKKSEKSEKKESKEGKKTEGKDEKSDNGTSGPNQESTKKTEEKKRISGKSPGHVVVLDQTKGDQGHSRTVRRGRFEKPQILRNKERIIQDKVKFREYRGRKDILPFEKMKEQRLREHMVRLERIRRAVELRRRREIAERERRERIRIMHEREECLQRERERLEIERQKLERERMERERLERERVRIEQERRKEAERIAREREELRRQQQQLRYEQEKRNALKRPRDVDHRRDDPYWNESKKMALDTDARFSHGSDYSRQPNRFNDFDHRERGRYPEGSVPSSSFDRRERFVNQGEAKKTRPTARREEPGFERYPKNFSDSRRNEPPPPRGKQIGRTKEA", "length": 849, "header": "tr|A0A8V0ZTI8-1|A0A8V0ZTI8_CHICK Computationally mapped isoform of SAFB-like transcription modulator OS=Gallus gallus OX=9031 GN=SLTM PE=1 SV=1 CANONICAL=A0A8V0ZSL6-1" }, "locus": { "chromosome": "10", "start_pos": 6912719, "end_pos": 6891777, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055870.1", "url": "https://www.ensembl.org/id/ENSGALT00010055870.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033821.1", "url": "https://www.ensembl.org/id/ENSGALP00010033821.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 18, "start_aa": "Thr", "end_pos": 18, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr18", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSL6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSL6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSL6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSL6" } ], "pmid": "" }, { "name": "nuclear body", "id": "GO:0016604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016604", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSL6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSL6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSL6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSL6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1002, "end_pos": 1004, "annotation": "n_glycosylation_sequon" }, { "start_pos": 239, "end_pos": 241, "annotation": "n_glycosylation_sequon" }, { "start_pos": 249, "end_pos": 251, "annotation": "n_glycosylation_sequon" }, { "start_pos": 537, "end_pos": 539, "annotation": "n_glycosylation_sequon" }, { "start_pos": 747, "end_pos": 749, "annotation": "n_glycosylation_sequon" }, { "start_pos": 826, "end_pos": 828, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZSL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSL6" }, { "id": "PS50102", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50102" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RRM", "eco_id": "ECO_0000259", "start_pos": 391, "end_pos": 469, "start_aa": "Arg", "end_aa": "Gly", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZSL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSL6" }, { "id": "PS50800", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50800" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SAP", "eco_id": "ECO_0000259", "start_pos": 33, "end_pos": 67, "start_aa": "Ile", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 18 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1002, "end_pos": 1004 }, { "start_pos": 239, "end_pos": 241 }, { "start_pos": 249, "end_pos": 251 }, { "start_pos": 537, "end_pos": 539 }, { "start_pos": 747, "end_pos": 749 }, { "start_pos": 826, "end_pos": 828 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", 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"field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZSM2-1", "uniprot_ac": "A0A8V0ZSM2", "uniprot_id": "A0A8V0ZSM2_CHICK", "mass": { "chemical_mass": 48954.0, "monoisotopic_mass": 48954.0 }, "refseq": { "ac": "XP_015141908", "name": "ras association domain-containing protein 10", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015141908" }, "gene_names": [ { "name": "RASSF10", "type": "recommended", "evidence": [ { "id": "A0A8V0ZSM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSM2" } ] }, { "name": "RASSF10", "type": "synonym", "evidence": [ { "id": "XP_015141908", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015141908" } ] } ], "protein_names": [ { "name": "Ras association domain family member 10", "type": "synonym", "evidence": [ { "id": "A0A8V0ZSM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSM2/entry#names_and_taxonomy" } ] }, { "name": "ras association domain-containing protein 10", "type": "synonym", "evidence": [ { "id": "XP_015141908", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015141908" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052536.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015141908.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015141908", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015141908" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSM2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSM2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RASSF10", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSM2", "locus": { "chromosome": "5", "start_pos": 7374313, "end_pos": 7377264, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021758", "url": "https://www.ensembl.org/id/ENSGALG00010021758" } ] } } ], "crossref": [ { "id": "A0A8V0ZSM2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZSM2", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd16132", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16132", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100859008", "url": "https://www.ncbi.nlm.nih.gov/gene/100859008", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000159", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000159", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029071", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029071", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033593", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033593", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033634", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033634", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:100859008", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100859008", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KADLDYS", "url": "https://omabrowser.org/oma/group/KADLDYS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZSM2", "url": "https://www.orthodb.org/?gene=A0A8V0ZSM2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15286", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15286", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15286:SF13", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15286:SF13", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF27976", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27976", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015141908", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015141908", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZSM2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSM2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZSM2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSM2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEPEERKISVWICQEEKLISGLSRRTTCSDVVRVLLEDSHHRRQRPAPPEPGGGMLSGPPHSYCIVEKWRGFERILPNKTKILRLWVAWGDEQENVRFVLVRSEASLPNAGPRSAEARVVLSRERPGHGLGAARASLALTQERQRRVVRKAFRKLAKINKKRQQPLAREASSAERMETLVHLVLSQDHTIRQQIQRLRELDREIDRYEAKIHLDRMKRHGVNYVQDTYLVGAGGEEPGREAQPGAGRPEDDYARKCEEVLQLQEQRARQEELLEHLAAEIQEELNERWMKRRRDELELAAGPGLAEADCHTTELSGGGEGELQLEHERVKTQLSTSLYIGLKLSTDLEAVKSDLDCTQRAWEARERELQRLLETLGTLDVAEAAAEPRGAAGGGWPEPGLRKDRADNDEDSDTGLSSMHSQDSDSVPVCESLV", "length": 433, "header": "tr|A0A8V0ZSM2-1|A0A8V0ZSM2_CHICK Isoform 1 of Ras association domain family member 10 OS=Gallus gallus OX=9031 GN=RASSF10 PE=4 SV=1 CANONICAL=A0A8V0ZSM2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZSM2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSM2/entry#A0A8V0ZSM2-1", "sequence": { "sequence": "MEPEERKISVWICQEEKLISGLSRRTTCSDVVRVLLEDSHHRRQRPAPPEPGGGMLSGPPHSYCIVEKWRGFERILPNKTKILRLWVAWGDEQENVRFVLVRSEASLPNAGPRSAEARVVLSRERPGHGLGAARASLALTQERQRRVVRKAFRKLAKINKKRQQPLAREASSAERMETLVHLVLSQDHTIRQQIQRLRELDREIDRYEAKIHLDRMKRHGVNYVQDTYLVGAGGEEPGREAQPGAGRPEDDYARKCEEVLQLQEQRARQEELLEHLAAEIQEELNERWMKRRRDELELAAGPGLAEADCHTTELSGGGEGELQLEHERVKTQLSTSLYIGLKLSTDLEAVKSDLDCTQRAWEARERELQRLLETLGTLDVAEAAAEPRGAAGGGWPEPGLRKDRADNDEDSDTGLSSMHSQDSDSVPVCESLV", "length": 433, "header": "tr|A0A8V0ZSM2-1|A0A8V0ZSM2_CHICK Isoform 1 of Ras association domain family member 10 OS=Gallus gallus OX=9031 GN=RASSF10 PE=4 SV=1 CANONICAL=A0A8V0ZSM2-1" }, "locus": { "chromosome": "5", "start_pos": 7374886, "end_pos": 7374313, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052897.1", "url": "https://www.ensembl.org/id/ENSGALT00010052897.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031803.1", "url": "https://www.ensembl.org/id/ENSGALP00010031803.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:100859008", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100859008", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A6NK89-1", "protein_name": "Ras association domain-containing protein 10", "gene_name": "RASSF10", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDPSEKKISVWICQEEKLVSGLSRRTTCSDVVRVLLEDGCRRRRRQRRSRRLGSAGDPHGPGELPEPPNEDDEDDDEALPQGMLCGPPQCYCIVEKWRGFERILPNKTRILRLWAAWGEEQENVRFVLVRSEASLPNAGPRSAEARVVLSRERPCPARGAPARPSLAMTQEKQRRVVRKAFRKLAKLNRRRQQQTPSSCSSTSSSTASSCSSSPRTHESASVERMETLVHLVLSQDHTIRQQVQRLHELDREIDHYEAKVHLDRMRRHGVNYVQDTYLVGAGIELDGSRPGEEPEEVAAEAEEAAAAPPLAGEAQAAALEELARRCDDLLRLQEQRVQQEELLERLSAEIQEELNQRWMRRRQEELAAREEPLEPDGGPDGELLLEQERVRTQLSTSLYIGLRLNTDLEAVKSDLDYSQQQWDSKKRELQGLLQTLHTLELTVAPDGAPGSGSPSREPGPQACADMWVDQARGLAKSGPGNDEDSDTGLSSMHSQDSDSLPMCESLV", "length": 507 }, "evidence": [ { "id": "A0A8V0ZSM2", "url": "https://omabrowser.org/oma/group/A0A8V0ZSM2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "E1BF74-1", "protein_name": "Ras association domain family member 10", "gene_name": "RASSF10", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MDPSEKKISVWICQEEKLVSGLSRRTTCSDVVRVLLEDGCRRRRRQRRSRRRGAAGDPPGPGELPEPLDEDDEDDDDEALPQGMLCGPPQCYCIVEKWRGFERILPNKTRILRLWAAWGEEQENVRFVLVRSEASLPNAGPRSAEARVVLSRERPCSARGVPARPSLAMTQEKQRRVVRKAFRKLAKLNRRRQQQPSSPCSSTSSSAASSCSSSSPRATESASVERMETLVHLVLSQDHTIRQQVQRLRELDREIDRYEAKVHLDRMRRHGVNYVQDTYLVGAGIELDGTGPGEEPEPEPDPEPAAATTTTPPLDGEAKAVALEELARRCDDLLQLQEQRAQQEELLERLSAEIQEELNQRWMRRRQEELATREEPPDAEGGLDGELLLERERVRTQLSTSLYIGLRLNTDLEAVKSDLDYSQQQWDSKERELQGLLQTLHTLELTVAPDGTPVSSGPSRDPGPQACAEVWVDQARGLAKSCPGNDEDSDTGLSSMHSQDSDSVPVCESLV", "length": 511 }, "evidence": [ { "id": "A0A8V0ZSM2", "url": "https://omabrowser.org/oma/group/A0A8V0ZSM2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8BL43-1", "protein_name": "Ras association domain-containing protein 10", "gene_name": "Rassf10", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": 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"database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZY59", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZY59", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZY59-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZY59-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTQQGALFPSLVPGSRGSSSKYLVEFRAGKMSLKGSTVTPDKRKGLVYIQQTDDSLIHFCWKDRTSGNVEDDLIIFPDDCEFKRVPQCTTGRVYVLKFKAGSKRLFFWMQEPKTDKDEEHCRKVNEYLNNPPMPGALGGNASGGHELSALGGEGGLQSLLGNMSHNQLMQLIGPTGLGGLGGLGALTGPGLASLLGSGGPPTSSSSSSSRSQSAAVTPSSTTSSTRVTPAPAVPAAASVTSPSPVPSSGNGTSSATSPTQPIQLSDLQNILATMNVPSGAGGQQVDLATVLTPEIMAPILANAEVQERLMPYLPSGESLPQTAEEIQNTLTSPQFQQALSMFSAALASGQLGPLMSQFGLPAEAIDAANKGDVEAFAKAMQNSVKSDQKEGDSKDKKDEEEDMSLD", "length": 406, "header": "tr|A0A8V0ZSM5-1|A0A8V0ZSM5_CHICK Isoform 1 of Adhesion regulating molecule 1 OS=Gallus gallus OX=9031 GN=ADRM1 PE=1 SV=1 CANONICAL=A0A8V0ZSM5-1" }, "isoforms": [ { "isoform_ac": "A0A1D5NTD3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSM5/entry#A0A1D5NTD3-1", "sequence": { "sequence": "MSSGALFPSLVPGSRGSSSKYLVEFRAGKMSLKGSTVTPDKRKGLVYIQQTDDSLIHFCWKDRTSGNVEDDLIIFPDDCEFKRVPQCTTGRVYVLKFKAGSKRLFFWMQEPKTDKDEEHCRKVNEYLNNPPMPGALGGNASGGHELSALGGEGGLQSLLGNMSHNQLMQLIGPTGLGGLGGLGALTGPGLASLLGSGGPPTSSSSSSSRSQSAAVTPSSTTSSTRVTPAPAVPAAASVTSPSPVPSSGNGTSSATSPTQPIQLSDLQNILATMNVPSGAGGQQVDLATVLTPEIMAPILANAEVQERLMPYLPSGESLPQTAEEIQNTLTSPQFQQALSMFSAALASGQLGPLMSQFGLPAEAIDAANKGDVEAFAKAMQNSVKSDQKEGDSKDKKDEEEDMSLD", "length": 405, "header": "tr|A0A1D5NTD3-1|A0A1D5NTD3_CHICK Computationally mapped isoform of Adhesion regulating molecule 1 OS=Gallus gallus OX=9031 GN=ADRM1 PE=1 SV=1 CANONICAL=A0A8V0ZSM5-1" }, "locus": { "chromosome": "20", "start_pos": 8173244, "end_pos": 8166966, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055901.1", "url": "https://www.ensembl.org/id/ENSGALT00010055901.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033839.1", "url": "https://www.ensembl.org/id/ENSGALP00010033839.1" } ] } }, { "isoform_ac": "A0A1D5PPT0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSM5/entry#A0A1D5PPT0-1", "sequence": { "sequence": "MSSGALFPSLVPGSRGSSSKYLVEFRAGKMSLKGSTVTPDKRKGLVYIQQTDDSLIHFCWKDRTSGNVEDDLIIFPDDCEFKRVPQCTTGRVYVLKFKAGSKRLFFWMQEPKTDKDEEHCRKVNEYLNNPPMPGALGGNASGGHELSALGGGLGALTGPGLASLLGSGGPPTSSSSSSSRSQSAAVTPSSTTSSTRVTPAPAVPAAASVTSPSPVPSSGNGTSSATSPTQPIQLSDLQNILATMNVPSGAGGQQVDLATVLTPEIMAPILANAEVQERLMPYLPSGESLPQTAEEIQNTLTSPQFQQALSMFSAALASGQLGPLMSQFGLPAEAIDAANKGDVEAFAKAMQNSVKSDQKEGDSKDKKDEEEDMSLD", "length": 376, "header": "tr|A0A1D5PPT0-1|A0A1D5PPT0_CHICK Computationally mapped isoform of Adhesion regulating molecule 1 OS=Gallus gallus OX=9031 GN=ADRM1 PE=1 SV=1 CANONICAL=A0A8V0ZSM5-1" }, "locus": { "chromosome": "20", "start_pos": 8173244, "end_pos": 8166966, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055895.1", "url": "https://www.ensembl.org/id/ENSGALT00010055895.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033836.1", "url": "https://www.ensembl.org/id/ENSGALP00010033836.1" } ] } }, { "isoform_ac": "A0A8V0ZQR7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSM5/entry#A0A8V0ZQR7-1", "sequence": { "sequence": "MSSGALFPSLVPGSRGSSSKYLVEFRAGKMSLKGSTVTPDKRKGLVYIQQTDDSLIHFCWKDRTSGNVEDDLIIFPDDCEFKRVPQCTTGRVYVLKFKAGSKRLFFWMQEPKTDKDEEHCRKVNEYLNNPPMPGALGGNASGGHELSALGGEGGLQSLLGNMSHNQLMQLIGPTGLGGLGGLGALTGPGLASLLGSGGPPTSSSSSSSRSQSAAVTPSSTTSSTRVTPAPAVPAAASVTSPSPVPSSGNGTSSATSPTQPIQLSDLQNILATMNVPSGAGGQQVDLATVLTPEIMAPILANAEVQERLMPYLPSGESLPQTAEEIQNTLTSPQFQQALSMFSAALASGQLGPLMSQFGLPAEAIDAANKGGMYQCCWERDELVGFAV", "length": 387, "header": "tr|A0A8V0ZQR7-1|A0A8V0ZQR7_CHICK Computationally mapped isoform of Adhesion regulating molecule 1 OS=Gallus gallus OX=9031 GN=ADRM1 PE=1 SV=1 CANONICAL=A0A8V0ZSM5-1" }, "locus": { "chromosome": "20", "start_pos": 8172514, "end_pos": 8166966, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055904.1", "url": "https://www.ensembl.org/id/ENSGALT00010055904.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033840.1", "url": "https://www.ensembl.org/id/ENSGALP00010033840.1" } ] } }, { "isoform_ac": "A0A8V0ZSM5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSM5/entry#A0A8V0ZSM5-1", "sequence": { "sequence": "MTQQGALFPSLVPGSRGSSSKYLVEFRAGKMSLKGSTVTPDKRKGLVYIQQTDDSLIHFCWKDRTSGNVEDDLIIFPDDCEFKRVPQCTTGRVYVLKFKAGSKRLFFWMQEPKTDKDEEHCRKVNEYLNNPPMPGALGGNASGGHELSALGGEGGLQSLLGNMSHNQLMQLIGPTGLGGLGGLGALTGPGLASLLGSGGPPTSSSSSSSRSQSAAVTPSSTTSSTRVTPAPAVPAAASVTSPSPVPSSGNGTSSATSPTQPIQLSDLQNILATMNVPSGAGGQQVDLATVLTPEIMAPILANAEVQERLMPYLPSGESLPQTAEEIQNTLTSPQFQQALSMFSAALASGQLGPLMSQFGLPAEAIDAANKGDVEAFAKAMQNSVKSDQKEGDSKDKKDEEEDMSLD", "length": 406, "header": "tr|A0A8V0ZSM5-1|A0A8V0ZSM5_CHICK Isoform 1 of Adhesion regulating molecule 1 OS=Gallus gallus OX=9031 GN=ADRM1 PE=1 SV=1 CANONICAL=A0A8V0ZSM5-1" }, "locus": { "chromosome": "20", "start_pos": 8173244, "end_pos": 8166286, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055898.1", "url": "https://www.ensembl.org/id/ENSGALT00010055898.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033837.1", "url": "https://www.ensembl.org/id/ENSGALP00010033837.1" } ] } }, { "isoform_ac": "A0A8V0ZTL1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSM5/entry#A0A8V0ZTL1-1", "sequence": { "sequence": "MSSGALFPSLVPGSRGSSSKYLVEFRAGKMSLKGSTVTPDKRKGLVYIQQTDDSLIHFCWKDRTSGNVEDDLIIFPDDCEFKRVPQCTTGRVYVLKFKAGSKRLFFWMQEPKTDKDEEHCRKVNEYLNNPPMPGALGGNASGGHELSALGGEGGLQSLLGNMSHNQLMQLIGPTGLGGLGGLGALTGPGLASLLGSGGPPTSSSSSSSRSQSAAVTPSSTTSSTRVTPAPAVPAAASVTSPSPVPSSGNGTSSATSPTQPIQLSDLQNILATMNVPSGAGGQQVDLATVLTPEIMAPILANAEVQERLMPYLPSGESLPQTAEEIQNTLTSPQFQQALSMFSAALASGQLGPLMSQFGLPAEAIDAANKGAQGGGDSSLSRCG", "length": 383, "header": "tr|A0A8V0ZTL1-1|A0A8V0ZTL1_CHICK Computationally mapped isoform of Adhesion regulating molecule 1 OS=Gallus gallus OX=9031 GN=ADRM1 PE=1 SV=1 CANONICAL=A0A8V0ZSM5-1" }, "locus": { "chromosome": "20", "start_pos": 8175711, "end_pos": 8166966, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055908.1", "url": "https://www.ensembl.org/id/ENSGALT00010055908.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033841.1", "url": "https://www.ensembl.org/id/ENSGALP00010033841.1" } ] } }, { "isoform_ac": "A0A8V0ZY59-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSM5/entry#A0A8V0ZY59-1", "sequence": { "sequence": "MSSGALFPSLVPGSRGSSSKYLVEFRAGKMSLKGSTVTPDKRKGLVYIQQTDDSLIHFCWKDRTSGNVEDDLIIFPDDCEFKRVPQCTTGRVYVLKFKAGSKRLFFWMQEPKTDKDEEHCRKVNEYLNNPPMPGALGGNASGGHELSALGGEGGLQSLLGNMSHNQLMQLIGPTGLGGLGGLGALTGPGLASLLGSGGPPTSSSSSSSRSQSAAVTPSSTTSSTRVTPAPAVPAAASVTSPSPVPSSGNGTSSATSPTQPIQLSDLQNILATMNVPSGAGGQQVDLATVLTPEIMAPILANAEVQERLMPYLPSGESLPQTAEEIQNTLTSPQFQQALSMFSAALASGQLGPLMSQFGLPAEAIDAANKGDSKDKKDEEEDMSLD", "length": 385, "header": "tr|A0A8V0ZY59-1|A0A8V0ZSM5_CHICK Computationally mapped isoform of Adhesion regulating molecule 1 OS=Gallus gallus OX=9031 GN=ADRM1 PE=1 SV=1 CANONICAL=A0A8V0ZSM5-1" }, "locus": { "chromosome": "20", "start_pos": 8173244, "end_pos": 8166966, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055889.1", "url": "https://www.ensembl.org/id/ENSGALT00010055889.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033834.1", "url": "https://www.ensembl.org/id/ENSGALP00010033834.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 217, "start_aa": "Thr", "end_pos": 217, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr217", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 228, "start_aa": "Thr", "end_pos": 228, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr228", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:395365", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395365", "resource": "KEGG Pathway" }, { "id": "R-GGA-1169091", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1169091", "resource": "Reactome", "description": "Activation of NF-kappaB in B cells" }, { "id": "R-GGA-1234176", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1234176", "resource": "Reactome", "description": "Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha" }, { "id": "R-GGA-1236978", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1236978", "resource": "Reactome", "description": "Cross-presentation of soluble exogenous antigens (endosomes)" }, { "id": "R-GGA-174084", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-174084", "resource": "Reactome", "description": "Autodegradation of Cdh1 by Cdh1:APC/C" }, { "id": "R-GGA-174154", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-174154", "resource": "Reactome", "description": "APC/C:Cdc20 mediated degradation of Securin" }, { "id": "R-GGA-174178", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-174178", "resource": "Reactome", "description": "APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1" }, { "id": "R-GGA-174184", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-174184", "resource": "Reactome", "description": "Cdc20:Phospho-APC/C mediated degradation of Cyclin A" }, { "id": "R-GGA-187577", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-187577", "resource": "Reactome", "description": "SCF(Skp2)-mediated degradation of p27/p21" }, { "id": "R-GGA-195253", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-195253", "resource": "Reactome", "description": "Degradation of beta-catenin by the destruction complex" }, { "id": "R-GGA-202424", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-202424", "resource": "Reactome", "description": "Downstream TCR signaling" }, { "id": "R-GGA-2467813", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2467813", "resource": "Reactome", "description": "Separation of Sister Chromatids" }, { "id": "R-GGA-2871837", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2871837", "resource": "Reactome", "description": "FCERI mediated NF-kB activation" }, { "id": "R-GGA-349425", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-349425", "resource": "Reactome", "description": "Autodegradation of the E3 ubiquitin ligase COP1" }, { "id": "R-GGA-350562", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-350562", "resource": "Reactome", "description": "Regulation of ornithine decarboxylase (ODC)" }, { "id": "R-GGA-382556", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-382556", "resource": "Reactome", "description": "ABC-family protein mediated transport" }, { "id": "R-GGA-450408", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-450408", "resource": "Reactome", "description": "AUF1 (hnRNP D0) binds and destabilizes mRNA" }, { "id": "R-GGA-4608870", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4608870", "resource": "Reactome", "description": "Asymmetric localization of PCP proteins" }, { "id": "R-GGA-4641257", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4641257", "resource": "Reactome", "description": "Degradation of AXIN" }, { "id": "R-GGA-4641258", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4641258", "resource": "Reactome", "description": "Degradation of DVL" }, { "id": "R-GGA-5358346", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5358346", "resource": "Reactome", "description": "Hedgehog ligand biogenesis" }, { "id": "R-GGA-5607764", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5607764", "resource": "Reactome", "description": "CLEC7A (Dectin-1) signaling" }, { "id": "R-GGA-5610780", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5610780", "resource": "Reactome", "description": "Degradation of GLI1 by the proteasome" }, { "id": "R-GGA-5610785", "name": "", "url": 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"id": "R-GGA-5689880", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5689880", "resource": "Reactome", "description": "Ub-specific processing proteases" }, { "id": "R-GGA-68867", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-68867", "resource": "Reactome", "description": "Assembly of the pre-replicative complex" }, { "id": "R-GGA-68949", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-68949", "resource": "Reactome", "description": "Orc1 removal from chromatin" }, { "id": "R-GGA-69017", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-69017", "resource": "Reactome", "description": "CDK-mediated phosphorylation and removal of Cdc6" }, { "id": "R-GGA-69601", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-69601", "resource": "Reactome", "description": "Ubiquitin-Mediated Degradation of Phosphorylated Cdc25A" }, { "id": "R-GGA-75815", "name": "", "url": 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635457, "end_pos": 622512, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010023317", "url": "https://www.ensembl.org/id/ENSGALG00010023317" } ] } } ], "crossref": [ { "id": "A0A8V0ZSN7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZSN7", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00038", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00038", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd00155", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00155", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd04437", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04437", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd06224", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06224", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000591", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000591", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000595", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000595", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000651", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000651", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001895", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001895", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008937", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008937", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014710", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014710", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018490", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018490", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019804", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019804", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023578", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023578", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029071", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029071", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036388", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036388", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036390", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036390", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036964", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036964", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZSN7", "url": "https://www.orthodb.org/?gene=A0A8V0ZSN7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZVW6", "url": "https://www.orthodb.org/?gene=A0A8V0ZVW6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23113", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23113", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23113:SF24", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23113:SF24", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00027", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00027", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00610", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00610", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00617", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00617", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00618", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00618", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-354192", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-354192", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-381676", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-381676", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-392517", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-392517", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-422356", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-422356", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZSN7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSN7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZSN7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSN7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZVW6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVW6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZVW6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVW6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKVRGAGTATATGTGTGIGSGGEAERRGAAPVGTHCGRTGLERCPGAVPPPTPPPPPSPGGSGGDGKRLSVLLKKMHLFRSSSYEIRLEGEGGSLPRIQGIRWTPLLDAESSLDYGHSLTQASSEKIWRAGKLLFTYLTSTSPSLIRDHKHHLRHHRRCCSGKELVDWMLNAELGIQTRSQAIGVGQVLVDGGVLTHVKQEWHFQDKDTQFYRFAELELSPEPRVGLRDAEELLEAVTFLAQLGPDALLTMALRKPPAQRTEDELELIFEELLHIKAVAHLSNSVKRELASVLMFESHQRAGTVLFSQGDKGTSWYIVWKGSVNVVTHGKGLVATLHEGDDFGQLALVNDAPRAASIILREDNCHFLRVDKQDFNRILKDVEANTMRLKEHGKVVLVLQKNLQGGSSQPAATRSSRYLVMAGTPEKILEHLLEFMRLDATLYDPVDTLLGDFLLTYTVFMPTSQLCRALLHHGPSFRAEPLDGSEQEKATYCLHKRRKILRLVSQWVLLYGRLLQGDRSTTALLQSLADLASQDPRLGAMVQEQERRRPRAMENGDGSISPQPKSRSSMSWLSSQDEAALSSSCALRAHDKVPYEVYRADHSCLVTVLPVNASVRDVLQSLTPQLGWDGEHLLVKVNSAGDKVGLQLDAVGVFTSLGLNERLFAVSMEELGGLTPHPEQLGPHVGSSDTLDLISSKDLASHLTDHDWNLFKSIHQVEMIHYIMGPQKFHEVTTANLERMMRRFNELQYWVATELCLCPELGRRAQLLRKFIKLAAHLKEQKNLNSFFAVMFGVSNTAVSRLAKTWERLPHKIRKLHAALERMLDPSWNHRVYRLAVAKLSPPIIPFVPLLLKDMTFIHEGNRTLAENLINFEKMHMMAKTVRILQRCRGQAHAPLSPLRNRSPHRPEDARAIRISTCSEQSLSVRSPVSTWAYLQHLRAIDSQKELLRLSRDLES", "length": 955, "header": "tr|A0A8V0ZSN7-1|A0A8V0ZSN7_CHICK Isoform 1 of Rap guanine nucleotide exchange factor 3 OS=Gallus gallus OX=9031 GN=RAPGEF3 PE=4 SV=1 CANONICAL=A0A8V0ZSN7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZSN7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSN7/entry#A0A8V0ZSN7-1", "sequence": { "sequence": "MKVRGAGTATATGTGTGIGSGGEAERRGAAPVGTHCGRTGLERCPGAVPPPTPPPPPSPGGSGGDGKRLSVLLKKMHLFRSSSYEIRLEGEGGSLPRIQGIRWTPLLDAESSLDYGHSLTQASSEKIWRAGKLLFTYLTSTSPSLIRDHKHHLRHHRRCCSGKELVDWMLNAELGIQTRSQAIGVGQVLVDGGVLTHVKQEWHFQDKDTQFYRFAELELSPEPRVGLRDAEELLEAVTFLAQLGPDALLTMALRKPPAQRTEDELELIFEELLHIKAVAHLSNSVKRELASVLMFESHQRAGTVLFSQGDKGTSWYIVWKGSVNVVTHGKGLVATLHEGDDFGQLALVNDAPRAASIILREDNCHFLRVDKQDFNRILKDVEANTMRLKEHGKVVLVLQKNLQGGSSQPAATRSSRYLVMAGTPEKILEHLLEFMRLDATLYDPVDTLLGDFLLTYTVFMPTSQLCRALLHHGPSFRAEPLDGSEQEKATYCLHKRRKILRLVSQWVLLYGRLLQGDRSTTALLQSLADLASQDPRLGAMVQEQERRRPRAMENGDGSISPQPKSRSSMSWLSSQDEAALSSSCALRAHDKVPYEVYRADHSCLVTVLPVNASVRDVLQSLTPQLGWDGEHLLVKVNSAGDKVGLQLDAVGVFTSLGLNERLFAVSMEELGGLTPHPEQLGPHVGSSDTLDLISSKDLASHLTDHDWNLFKSIHQVEMIHYIMGPQKFHEVTTANLERMMRRFNELQYWVATELCLCPELGRRAQLLRKFIKLAAHLKEQKNLNSFFAVMFGVSNTAVSRLAKTWERLPHKIRKLHAALERMLDPSWNHRVYRLAVAKLSPPIIPFVPLLLKDMTFIHEGNRTLAENLINFEKMHMMAKTVRILQRCRGQAHAPLSPLRNRSPHRPEDARAIRISTCSEQSLSVRSPVSTWAYLQHLRAIDSQKELLRLSRDLES", "length": 955, "header": "tr|A0A8V0ZSN7-1|A0A8V0ZSN7_CHICK Isoform 1 of Rap guanine nucleotide exchange factor 3 OS=Gallus gallus OX=9031 GN=RAPGEF3 PE=4 SV=1 CANONICAL=A0A8V0ZSN7-1" }, "locus": { "chromosome": "34", "start_pos": 635255, "end_pos": 622654, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056853.1", "url": "https://www.ensembl.org/id/ENSGALT00010056853.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034566.1", "url": "https://www.ensembl.org/id/ENSGALP00010034566.1" } ] } }, { "isoform_ac": "A0A8V0ZVW6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSN7/entry#A0A8V0ZVW6-1", "sequence": { "sequence": "MWPWRGLSIAAVVIWMGHPLWLNRSCSRLQRAEQHPWALLLESIIFSILLSWMRLQSWRRSLGLSLALPSPQTPLLDAESSLDYGHSLTQASSEKIWRAGKLLFTYLTSTSPSLIRDHKHHLRHHRRCCSGKELVDWMLNAELGIQTRSQAIGVGQVLVDGGVLTHVKQEWHFQDKDTQFYRFAELELSPEPRVGLRDAEELLEAVTFLAQLGPDALLTMALRKPPAQRTEDELELIFEELLHIKAVAHLSNSVKRELASVLMFESHQRAGTVLFSQGDKGTSWYIVWKGSVNVVTHGKGLVATLHEGDDFGQLALVNDAPRAASIILREDNCHFLRVDKQDFNRILKDVEANTMRLKEHGKVVLVLQKNLQGGSSQPAATRSSRYLVMAGTPEKILEHLLEFMRLDATLYDPVDTLLGDFLLTYTVFMPTSQLCRALLHHFRAEPLDGSEQEKATYCLHKRRKILRLVSQWVLLYGRLLQGDRSTTALLQSLADLASQDPRLGAMVQEQERRRPRAMENGDGSISPQPKSRSSMSWLSSQDEAALSSSCALRAHDKVPYEVYRADHSCLVTVLPVNASVRDVLQSLTPQLGWDGEHLLVKVNSAGDKVGLQLDAVGVFTSLGLNERLFAVSMEELGGLTPHPEQLGPHVGSSDTLDLISSKDLASHLTDHDWNLFKSIHQVEMIHYIMGPQKFHEVTTANLERMMRRFNELQYWVATELCLCPELGRRAQLLRKFIKLAAHLKEQKNLNSFFAVMFGVSNTAVSRLAKTWERLPHKIRKLHAALERMLDPSWNHRVYRLAVAKLSPPIIPFVPLLLKDMTFIHEGNRTLAENLINFEKMHMMAKTVRILQRCRGQAHAPLSPLRNRSPHRPEDARAIRISTCSEQSLSVRSPVSTWAYLQHLRAIDSQKELLRLSRDLES", "length": 921, "header": "tr|A0A8V0ZVW6-1|A0A8V0ZSN7_CHICK Computationally mapped isoform of Rap guanine nucleotide exchange factor 3 OS=Gallus gallus OX=9031 GN=RAPGEF3 PE=4 SV=1 CANONICAL=A0A8V0ZSN7-1" }, "locus": { "chromosome": "34", "start_pos": 635255, "end_pos": 626386, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056848.1", "url": "https://www.ensembl.org/id/ENSGALT00010056848.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034562.1", "url": "https://www.ensembl.org/id/ENSGALP00010034562.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 52, "start_aa": "Thr", "end_pos": 52, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr52", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-GGA-354192", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-354192", "resource": "Reactome", "description": "Integrin signaling" }, { "id": "R-GGA-381676", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-381676", "resource": "Reactome", "description": "Glucagon-like Peptide-1 (GLP1) regulates insulin secretion" }, { "id": "R-GGA-392517", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-392517", "resource": "Reactome", "description": "Rap1 signalling" }, { "id": "R-GGA-422356", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-422356", "resource": "Reactome", "description": "Regulation of insulin secretion" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 11, "go_terms": [ { "name": "regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction", "id": "GO:0051896", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051896", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSN7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSN7" } ], "pmid": "" }, { "name": "establishment of endothelial barrier", "id": "GO:0061028", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061028", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSN7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSN7" } ], "pmid": "" }, { "name": "Rap protein signal transduction", "id": "GO:0032486", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032486", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSN7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSN7" } ], "pmid": "" }, { "name": "associative learning", "id": "GO:0008306", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008306", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSN7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSN7" } ], "pmid": "" }, { "name": "cellular response to cAMP", "id": "GO:0071320", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071320", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSN7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSN7" } ], "pmid": "" }, { "name": "positive regulation of angiogenesis", "id": "GO:0045766", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045766", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSN7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSN7" } ], "pmid": "" }, { "name": "positive regulation of protein export from nucleus", "id": "GO:0046827", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046827", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSN7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSN7" } ], "pmid": "" }, { "name": "positive regulation of stress fiber assembly", "id": "GO:0051496", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051496", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSN7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSN7" } ], "pmid": "" }, { "name": "negative regulation of syncytium formation by plasma membrane fusion", "id": "GO:0034242", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034242", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSN7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSN7" } ], "pmid": "" }, { "name": "positive regulation of syncytium formation by plasma membrane fusion", "id": "GO:0060143", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060143", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSN7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSN7" } ], "pmid": "" }, { "name": "small GTPase-mediated signal transduction", "id": "GO:0007264", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007264", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSN7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSN7" } ], "pmid": "" } ] }, { "name": "Cellular 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} ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZSQ8-1", "uniprot_ac": "A0A8V0ZSQ8", "uniprot_id": "A0A8V0ZSQ8_CHICK", "mass": { "chemical_mass": 67125.0, "monoisotopic_mass": 67125.0 }, "refseq": { "ac": "NP_001378820", "name": "interactor of HORMAD1 protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001378820" }, "gene_names": [ { "name": "CCDC36", "type": "recommended", "evidence": [ { "id": "A0A8V0ZSQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSQ8" } ] }, { "name": "CCDC36", "type": "synonym", "evidence": [ { "id": "NP_001378820", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001378820" } ] } ], "protein_names": [ { "name": "Coiled-coil domain containing 36", "type": "synonym", "evidence": [ { "id": "A0A8V0ZSQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSQ8/entry#names_and_taxonomy" } ] }, { "name": "interactor of HORMAD1 protein 1", "type": "synonym", "evidence": [ { "id": "NP_001378820", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001378820" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMEA103992290 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000252.1. On Nov 20, 2021 this sequence version replaced NP_001378820.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001378820", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001378820" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSQ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSQ8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CCDC36", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSQ8", "locus": { "chromosome": "12", "start_pos": 11689677, "end_pos": 11709739, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021775", "url": "https://www.ensembl.org/id/ENSGALG00010021775" } ] } } ], "crossref": [ { "id": "A0A8V0ZSQ8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZSQ8", "database": "AlphaFoldDB", "categories": [] }, { "id": "101750778", "url": "https://www.ncbi.nlm.nih.gov/gene/101750778", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR031529", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031529", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "WNKAMGR", "url": "https://omabrowser.org/oma/group/WNKAMGR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZSQ8", "url": "https://www.orthodb.org/?gene=A0A8V0ZSQ8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR35662", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR35662", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR35662:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR35662:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15771", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15771", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001378820", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001378820", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZSQ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSQ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZSQ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSQ8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNFNVWNIKEMLSTPTASGPNKFLARSSALSDYSSLSDSQVLFGSQFCPENVQSAAPLELGMQLGQHNSQDSEPSIFTKYQAKPQLFDEDTREKGLLNFGAGQGKTVLENFKANKNKIKDKYDREVLSTFISSINERLQGLQTCLDKLEEEFNSRNKSISVHLETISKTLQDALQSHSDVVLKALEDKSQMEQALLEMERRLAAKDVEISDVKSSVLQLKEGLESLPAQLGDHHLKLCEELHSLKLPSALAELQTFMSSARVPPRMMDNSSQTSPGTCQDCAPHQQKAHWLCCHGMGGCSSLGLSAAGKQHGVTGDVTPRDGFSTASESKVSPVATAVESSLVAQSCSHHPCVCSANSQFLGDGRKKHIPILQEISPVTPLRKAIRRGTRGFKPVTPSQQRQPQVCHLFVQSDVSGQRDGNSSTDQELENIAVGNKAKQKLGRIPWNKVVERKKTYPGKRKGELTTCADGGLKQVRANRIIGSGSTRKNRFPRYTVAVSLASSNPISTAPHQQMLSSAQPRLTRSFLPVPCSNKSMLQLADQRKRSLENKKRVIVSSVRRDFWDSSPQESLFSLCRTGEKQASCSPGSTNPCPGNVQGTECCSLVFDSDYSD", "length": 612, "header": "tr|A0A8V0ZSQ8-1|A0A8V0ZSQ8_CHICK Isoform 1 of Coiled-coil domain containing 36 OS=Gallus gallus OX=9031 GN=CCDC36 PE=4 SV=1 CANONICAL=A0A8V0ZSQ8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZSQ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSQ8/entry#A0A8V0ZSQ8-1", "sequence": { "sequence": "MNFNVWNIKEMLSTPTASGPNKFLARSSALSDYSSLSDSQVLFGSQFCPENVQSAAPLELGMQLGQHNSQDSEPSIFTKYQAKPQLFDEDTREKGLLNFGAGQGKTVLENFKANKNKIKDKYDREVLSTFISSINERLQGLQTCLDKLEEEFNSRNKSISVHLETISKTLQDALQSHSDVVLKALEDKSQMEQALLEMERRLAAKDVEISDVKSSVLQLKEGLESLPAQLGDHHLKLCEELHSLKLPSALAELQTFMSSARVPPRMMDNSSQTSPGTCQDCAPHQQKAHWLCCHGMGGCSSLGLSAAGKQHGVTGDVTPRDGFSTASESKVSPVATAVESSLVAQSCSHHPCVCSANSQFLGDGRKKHIPILQEISPVTPLRKAIRRGTRGFKPVTPSQQRQPQVCHLFVQSDVSGQRDGNSSTDQELENIAVGNKAKQKLGRIPWNKVVERKKTYPGKRKGELTTCADGGLKQVRANRIIGSGSTRKNRFPRYTVAVSLASSNPISTAPHQQMLSSAQPRLTRSFLPVPCSNKSMLQLADQRKRSLENKKRVIVSSVRRDFWDSSPQESLFSLCRTGEKQASCSPGSTNPCPGNVQGTECCSLVFDSDYSD", "length": 612, "header": "tr|A0A8V0ZSQ8-1|A0A8V0ZSQ8_CHICK Isoform 1 of Coiled-coil domain containing 36 OS=Gallus gallus OX=9031 GN=CCDC36 PE=4 SV=1 CANONICAL=A0A8V0ZSQ8-1" }, "locus": { "chromosome": "12", "start_pos": 11708664, "end_pos": 11690814, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052938.1", "url": "https://www.ensembl.org/id/ENSGALT00010052938.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031844.1", "url": "https://www.ensembl.org/id/ENSGALP00010031844.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "condensed nuclear chromosome", "id": "GO:0000794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000794", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSQ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSQ8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "DNA recombination", "id": "GO:0006310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006310", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSQ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSQ8" } ], "pmid": "" }, { "name": "homologous chromosome pairing at meiosis", "id": "GO:0007129", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007129", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSQ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSQ8" } ], "pmid": "" }, { "name": "meiotic DNA double-strand break formation", "id": "GO:0042138", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042138", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSQ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSQ8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 156, "end_pos": 158, "annotation": "n_glycosylation_sequon" }, { "start_pos": 269, "end_pos": 271, "annotation": "n_glycosylation_sequon" }, { "start_pos": 421, "end_pos": 423, "annotation": "n_glycosylation_sequon" }, { "start_pos": 533, "end_pos": 535, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 156, "end_pos": 158 }, { "start_pos": 269, "end_pos": 271 }, { "start_pos": 421, "end_pos": 423 }, { "start_pos": 533, "end_pos": 535 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZSS0-1", "uniprot_ac": "A0A8V0ZSS0", "uniprot_id": "A0A8V0ZSS0_CHICK", "mass": { "chemical_mass": 167441.0, "monoisotopic_mass": 167441.0 }, "refseq": { "ac": "XP_040535594", "name": "vacuolar protein sorting-associated protein 8 homolog isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040535594" }, "gene_names": [ { "name": "VPS8", "type": "recommended", "evidence": [ { "id": "A0A8V0ZSS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSS0" } ] }, { "name": "VPS8", "type": "synonym", "evidence": [ { "id": "XP_040535594", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040535594" } ] } ], "protein_names": [ { "name": "Vacuolar protein sorting-associated protein 8 homolog", "type": "recommended", "evidence": [ { "id": "A0A8V0ZSS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSS0/entry#names_and_taxonomy" } ] }, { "name": "vacuolar protein sorting-associated protein 8 homolog isoform X2", "type": "synonym", "evidence": [ { "id": "XP_040535594", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040535594" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052581.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040535594", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040535594" } ] }, { "annotation": "Plays a role in vesicle-mediated protein trafficking of the endocytic membrane transport pathway. Believed to act as a component of the putative CORVET endosomal tethering complexes which is proposed to be involved in the Rab5-to-Rab7 endosome conversion probably implicating MON1A/B, and via binding SNAREs and SNARE complexes to mediate tethering and docking events during SNARE-mediated membrane fusion. The CORVET complex is proposed to function as a Rab5 effector to mediate early endosome fusion probably in specific endosome subpopulations. Functions predominantly in APPL1-containing endosomes.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A5D5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5D5#function" }, { "database": "UniProtKB", "id": "ARBA00059958", "url": "https://www.uniprot.org/uniprotkb/ARBA00059958#function" }, { "database": "UniProtKB", "id": "A0A8V1A5E0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5E0#function" }, { "database": "UniProtKB", "id": "A0A8V0ZSS0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSS0#function" }, { "database": "UniProtKB", "id": "A0A8V0ZSR2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSR2#function" }, { "database": "UniProtKB", "id": "A0A8V0ZXW8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXW8#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSS0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSS0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "VPS8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSS0", "locus": { "chromosome": "9", "start_pos": 3187541, "end_pos": 3121519, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010024502", "url": "https://www.ensembl.org/id/ENSGALG00010024502" } ] } } ], "crossref": [ { "id": "cd16687", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16687", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "429138", "url": "https://www.ncbi.nlm.nih.gov/gene/429138", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011044", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011044", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025941", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025941", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045111", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045111", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056939", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056939", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZSR2", "url": "https://www.orthodb.org/?gene=A0A8V0ZSR2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZSS0", "url": "https://www.orthodb.org/?gene=A0A8V0ZSS0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZXW8", "url": "https://www.orthodb.org/?gene=A0A8V0ZXW8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A5D5", "url": "https://www.orthodb.org/?gene=A0A8V1A5D5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A5E0", "url": "https://www.orthodb.org/?gene=A0A8V1A5E0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12616", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12616", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12616:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12616:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12816", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12816", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23410", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23410", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23412", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23412", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040535594", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040535594", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZSR2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSR2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZSR2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSR2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZSS0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSS0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZSS0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSS0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZXW8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXW8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZXW8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXW8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A5D5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5D5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A5D5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5D5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A5E0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5E0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A5E0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5E0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSPMISFSPPAGSRSRRTRVRFRKRRPGAAARFPINRSVPSPPPLSYRRAAAPLTAARGGRRCRAAHARSGGGSGRGFESRRRRPAHPAASRSPAMDAAPEDGPAGAEAEPDGLPCPEPPAPRLSVAELDRELDSRSELIDDKEFDIPQVDTPPTLESILNETDDEEESFVLEDPFLLNIDNTDTHSYDTSSVASSDSGDRTHLKRKKKLPDSLSLHGSVIRLSLLKGISAQIVSAADKVDAGLPTAIAASNLIAVGTSHGLALIFDQNQALRLCLGSTAVGAQYGAISALSINNDCSRLLCGFAKGQITMWDLASGKLLRSITDAHPPGTAILHIKFTDDPTLAICNDSGGSVFELSFKRVMGVRTCESRCLFSGSKGEVCCIEPLHAKVELRDHPITQYSLLAMASLTKILVIGLKPSLKVWMTFPYGRMDPSSVPLLAWHFVAVQNSVNPMLAFCRGDVVHFLLVKRDDTGAIHVTKQKQLHLHYDLINFTWINSRTAVLLDSVEKLHVIDRQTQEELETIEIPEVQLVYNSSHFKSLATGGNVSEALALVGEKACYQSISSCGGQIFYLGTKSVHVMTLRSWRERIDHLLKQERLTDALALAWSFYEGKAKAVVGLSGDTSKRKAVIADRMVEILLHYADRTLKKCPDQGKIQVMEQHFQDVVPVIVDYCLLLQRTDLLFNQIYDKMSENSVAKGIFLECLEPYILSDKLMGITAQVMKDLLLHFQDKNRLENMEACIVHMDITSLDIQQVVLLCWENHLYDAMIYVYNSGMNDFISPMEKLLKVIAPPLDAGKSLTDEQVVMGNKLLVYISCCLAGRAYPLGDIPEDLVPLVKNQIFEFLIRLHSTEGSVDEEVYPHIRTLLHFDTREFLNVLALTFEDFKNDKQAVEYQQRIVDILLKVMVENSDFTPSQVGCLFTFLARQLAKPNNTLFVNRTLFDQVLEFLCSPDDDSRHSERQQVLLELLQAGGIVQFEESRLIQMAEKAEFYQICEFMYERELRYDKIIDCYLRDPVRKEEVFNYIHNILSMPGYSAEEKQSVWQKALEHIEELLLLSPCKAADLVAIHFTEQIESIIANLQDQFLLFQFLRSLLDPREGINQDLLHLPPHVTEQFIELLCQHSPEHVLETLKVLEYCRLEETIQITQKHQLHEASSYLLEKKGDIHGAFLVMLERLQSKLLMLTQDDGGSAELPLLESIEDTLMKTIALCQRNSHNLNQQQREALWFPLLEAMMSPQKLSGSSQYRYAESLKSLTMQVLNNMAAFIPLPLILQRILQDPVYGKGKLGEIQGLILGMLDTFNYEQTLLETTTNLLNHDLHWSLCNLRASVTRGLTPKQDYCCICLQQYKRRQESADEIIVFSCGHLYHSLCLLSKECGAVSKDVMRWMCYKCNLSNKGGKLSENFSELKKGSGTSLAQTGSESALDPQQIQAFDQLCRLNRGTSRLALLTELSRAHGGEKHGLLSVSHGDSAASSVFQDETFQLHLAPPPLMDD", "length": 1494, "header": "tr|A0A8V0ZSS0-1|A0A8V0ZSS0_CHICK Isoform 1 of Vacuolar protein sorting-associated protein 8 homolog OS=Gallus gallus OX=9031 GN=VPS8 PE=3 SV=1 CANONICAL=A0A8V0ZSS0-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZSR2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSS0/entry#A0A8V0ZSR2-1", "sequence": { "sequence": "MDAAPEDGPAGAEAEPDGLPCPEPPAPRLSVAELDRELDSRSELIDDKEFDIPQVDTPPTLESILNETDDEEESFVLEDPFLLNIDNTDTHSYDTSSVASSDSGDRTHLKRKKKLPDSLSLHGSVIRLSLLKGISAQIVSAADKVDAGLPTAIAASNLIAVGTSHGLALIFDQNQALRLCLGSTAVGAQYGAISALSINNDCSRLLCGFAKGQITMWDLASGKLLRSITDAHPPGTAILHIKFTDDPTLAICNDSGGSVFELSFKRVMGVRTCESRCLFSGSKGEVCCIEPLHAKVELRDHPITQYSLLAMASLTKILVIGLKPSLKVWMTFPYGRMDPSSVPLLAWHFVAVQNSVNPMLAFCRGDVVHFLLVKRDDTGAIHVTKQKQLHLHYDLINFTWINSRTAVLLDSVEKLHVIDRQTQEELETIEIPEVQLVYNSSHFKSLATGGNVSEALALVGEKACYQSISSCGGQIFYLGTKSVHVMTLRSWRERIDHLLKQERLTDALALAWSFYEGKAKAVVGLSGDTSKRKAVIADRMVEILLHYADRTLKKCPDQGKIQVMEQHFQDVVPVIVDYCLLLQRTDLLFNQIYDKMSENSVAKGIFLECLEPYILSDKLMGITAQVMKDLLLHFQDKNRLENMEACIVHMDITSLDIQQVVLLCWENHLYDAMIYVYNSGMNDFISPMEKLLKVIAPPLDAGKSLTDEQVVMGNKLLVYISCCLAGRAYPLGDIPEDLVPLVKNQIFEFLIRLHSTEGSVDEEVYPHIRTLLHFDTREFLNVLALTFEDFKNDKQAVEYQQRIVDILLKVMVENSDFTPSQVGCLFTFLARQLAKPNNTLFVNRTLFDQVLEFLCSPDDDSRHSERQQVLLELLQAGGIVQFEESRLIQMAEKAEFYQICEFMYERELRYDKIIDCYLRDPVRKELLLLSPCKAADLVAIHFTEQIESIIANLQDQFLLFQFLRSLLDPREGINQDLLHLPPHVTEQFIELLCQHSPEHVLETLKVLEYCRLEETIQITQKHQLHEASSYLLEKKGDIHGAFLVMLERLQSKLLMLTQDDGGSAELPLLESIEDTLMKTIALCQRNSHNLNQQQREALWFPLLEAMMSPQKLSGSSQYRYAESLKSLTMQVLNNMAAFIPLPLILQRILQDPVYGKGKLGEIQGLILGMLDTFNYEQTLLETTTNLLNHDLHWSLCNLRASVTRGLTPKQDYCCICLQQYKRRQESADEIIVFSCGHLYHSLCLLSKECGAVSKDVMRWMCYKCNLSNKGGKLSENFSELKKGSGTSLAQTGSESALDPQQIQAFDQLCRLNRGTSRLALLTELSRAHGGEKHGLLSVSHGDSAASSVFQDETFQLHLAPPPLMDD", "length": 1366, "header": "tr|A0A8V0ZSR2-1|A0A8V0ZSS0_CHICK Computationally mapped isoform of Vacuolar protein sorting-associated protein 8 homolog OS=Gallus gallus OX=9031 GN=VPS8 PE=3 SV=1 CANONICAL=A0A8V0ZSS0-1" }, "locus": { "chromosome": "9", "start_pos": 3187111, "end_pos": 3122003, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010059778.1", "url": "https://www.ensembl.org/id/ENSGALT00010059778.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036538.1", "url": "https://www.ensembl.org/id/ENSGALP00010036538.1" } ] } }, { "isoform_ac": "A0A8V0ZSS0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSS0/entry#A0A8V0ZSS0-1", "sequence": { "sequence": "MSPMISFSPPAGSRSRRTRVRFRKRRPGAAARFPINRSVPSPPPLSYRRAAAPLTAARGGRRCRAAHARSGGGSGRGFESRRRRPAHPAASRSPAMDAAPEDGPAGAEAEPDGLPCPEPPAPRLSVAELDRELDSRSELIDDKEFDIPQVDTPPTLESILNETDDEEESFVLEDPFLLNIDNTDTHSYDTSSVASSDSGDRTHLKRKKKLPDSLSLHGSVIRLSLLKGISAQIVSAADKVDAGLPTAIAASNLIAVGTSHGLALIFDQNQALRLCLGSTAVGAQYGAISALSINNDCSRLLCGFAKGQITMWDLASGKLLRSITDAHPPGTAILHIKFTDDPTLAICNDSGGSVFELSFKRVMGVRTCESRCLFSGSKGEVCCIEPLHAKVELRDHPITQYSLLAMASLTKILVIGLKPSLKVWMTFPYGRMDPSSVPLLAWHFVAVQNSVNPMLAFCRGDVVHFLLVKRDDTGAIHVTKQKQLHLHYDLINFTWINSRTAVLLDSVEKLHVIDRQTQEELETIEIPEVQLVYNSSHFKSLATGGNVSEALALVGEKACYQSISSCGGQIFYLGTKSVHVMTLRSWRERIDHLLKQERLTDALALAWSFYEGKAKAVVGLSGDTSKRKAVIADRMVEILLHYADRTLKKCPDQGKIQVMEQHFQDVVPVIVDYCLLLQRTDLLFNQIYDKMSENSVAKGIFLECLEPYILSDKLMGITAQVMKDLLLHFQDKNRLENMEACIVHMDITSLDIQQVVLLCWENHLYDAMIYVYNSGMNDFISPMEKLLKVIAPPLDAGKSLTDEQVVMGNKLLVYISCCLAGRAYPLGDIPEDLVPLVKNQIFEFLIRLHSTEGSVDEEVYPHIRTLLHFDTREFLNVLALTFEDFKNDKQAVEYQQRIVDILLKVMVENSDFTPSQVGCLFTFLARQLAKPNNTLFVNRTLFDQVLEFLCSPDDDSRHSERQQVLLELLQAGGIVQFEESRLIQMAEKAEFYQICEFMYERELRYDKIIDCYLRDPVRKEEVFNYIHNILSMPGYSAEEKQSVWQKALEHIEELLLLSPCKAADLVAIHFTEQIESIIANLQDQFLLFQFLRSLLDPREGINQDLLHLPPHVTEQFIELLCQHSPEHVLETLKVLEYCRLEETIQITQKHQLHEASSYLLEKKGDIHGAFLVMLERLQSKLLMLTQDDGGSAELPLLESIEDTLMKTIALCQRNSHNLNQQQREALWFPLLEAMMSPQKLSGSSQYRYAESLKSLTMQVLNNMAAFIPLPLILQRILQDPVYGKGKLGEIQGLILGMLDTFNYEQTLLETTTNLLNHDLHWSLCNLRASVTRGLTPKQDYCCICLQQYKRRQESADEIIVFSCGHLYHSLCLLSKECGAVSKDVMRWMCYKCNLSNKGGKLSENFSELKKGSGTSLAQTGSESALDPQQIQAFDQLCRLNRGTSRLALLTELSRAHGGEKHGLLSVSHGDSAASSVFQDETFQLHLAPPPLMDD", "length": 1494, "header": "tr|A0A8V0ZSS0-1|A0A8V0ZSS0_CHICK Isoform 1 of Vacuolar protein sorting-associated protein 8 homolog OS=Gallus gallus OX=9031 GN=VPS8 PE=3 SV=1 CANONICAL=A0A8V0ZSS0-1" }, "locus": { "chromosome": "9", "start_pos": 3187111, "end_pos": 3121718, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010059788.1", "url": "https://www.ensembl.org/id/ENSGALT00010059788.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036548.1", "url": "https://www.ensembl.org/id/ENSGALP00010036548.1" } ] } }, { "isoform_ac": "A0A8V0ZXW8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSS0/entry#A0A8V0ZXW8-1", "sequence": { "sequence": "MDAAPEDGPAGAEAEPDGLPCPEPPAPRLSVAELDRELDSRSELIDDKEFDIPQVDTPPTLESILNETDDEEESFVLEDPFLLNIDNTDTHSYDTSSVASSDSGDRTHLKRKKKLPDSLSLHGSVIRLSLLKGISAQIVSAADKVDAGLPTAIAASNLIAVGTSHGLALIFGKDQNQALRLCLGSTAVGAQYGAISALSINNDCSRLLCGFAKGQITMWDLASGKLLRSITDAHPPGTAILHIKFTDDPTLAICNDSGGSVFELSFKRVMGVRTCESRCLFSGSKGEVCCIEPLHAKVELRDHPITQYSLLAMASLTKILVIGLKPSLKVWMTFPYGRMDPSSVPLLAWHFVAVQNSVNPMLAFCRGDVVHFLLVKRDDTGAIHVTKQKQLHLHYDLINFTWINSRTAVLLDSVEKLHVIDRQTQEELETIEIPEVQLVYNSSHFKSLATGGNVSEALALVGEKACYQSISSCGGQIFYLGTKSVHVMTLRSWRERIDHLLKQERLTDALALAWSFYEGKAKAVVGLSGDTSKRKAVIADRMVEILLHYADRTLKKCPDQGKIQVMEQHFQDVVPVIVDYCLLLQRTDLLFNQIYDKMSENSVAKGIFLECLEPYILSDKLMGITAQVMKDLLLHFQDKNRLENMEACIVHMDITSLDIQQVVLLCWENHLYDAMIYVYNSGMNDFISPMEKLLKVIAPPLDAGKSLTDEQVVMGNKLLVYISCCLAGRAYPLGDIPEDLVPLVKNQIFEFLIRLHSTEGSVDEEVYPHIRTLLHFDTREFLNVLALTFEDFKNDKQAVEYQQRIVDILLKVMVENSDFTPSQVGCLFTFLARQLAKPNNTLFVNRTLFDQVLEFLCSPDDDSRHSERQQVLLELLQAGGIVQFEESRLIQMAEKAEFYQICEFMYERELRYDKIIDCYLRDPVRKEEVFNYIHNILSMPGYSAEEKQSVWQKALEHIEELLLLSPCKAADLVAIHFTEQIESIIANLQDQFLLFQFLRSLLDPREGINQDLLHLPPHVTEQFIELLCQHSPEHVLETLKVLEYCRLEETIQITQKHQLHEASSYLLEKKGDIHGAFLVMLERLQSKLLMLTQDDGGSAELPLLESIEDTLMKTIALCQRNSHNLNQQQREALWFPLLEAMMSPQKLSGSSQYRYAESLKSLTMQVLNNMAAFIPLPLILQRILQDPVYGKGKLGEIQGLILGMLDTFNYEQTLLETTTNLLNHDLHWSLCNLRASVTRGLTPKQDYCCICLQQYKRRQESADEIIVFSCGHLYHSLCLLSKECGAVSKDVMRWMCYKCNLSNKGGKLSENFSELKKGSGTSLAQTGSESALDPQQIQAFDQLCRLNRGTSRLALLTELSRAHGGEKHGLLSVSHGDSAASSVFQDETFQLHLAPPPLMDD", "length": 1401, "header": "tr|A0A8V0ZXW8-1|A0A8V0ZSS0_CHICK Computationally mapped isoform of Vacuolar protein sorting-associated protein 8 homolog OS=Gallus gallus OX=9031 GN=VPS8 PE=3 SV=1 CANONICAL=A0A8V0ZSS0-1" }, "locus": { "chromosome": "9", "start_pos": 3187111, "end_pos": 3122003, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010059775.1", "url": "https://www.ensembl.org/id/ENSGALT00010059775.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036535.1", "url": "https://www.ensembl.org/id/ENSGALP00010036535.1" } ] } }, { "isoform_ac": "A0A8V1A5D5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSS0/entry#A0A8V1A5D5-1", "sequence": { "sequence": "MRRVAVRRDLTPIDDKEFDIPQVDTPPTLESILNETDDEEESFVLEDPFLLNIDNTDTHSYDTSSVASSDSGDRTHLKRKKKLPDSLSLHGSVIRLSLLKGISAQIVSAADKVDAGLPTAIAASNLIAVGTSHGLALIFDQNQALRLCLGSTAVGAQYGAISALSINNDCSRLLCGFAKGQITMWDLASGKLLRSITDAHPPGTAILHIKFTDDPTLAICNDSGGSVFELSFKRVMGVRTCESRCLFSGSKGEVCCIEPLHAKVELRDHPITQYSLLAMASLTKILVIGLKPSLKVWMTFPYGRMDPSSVPLLAWHFVAVQNSVNPMLAFCRGDVVHFLLVKRDDTGAIHVTKQKQLHLHYDLINFTWINSRTAVLLDSVEKLHVIDRQTQEELETIEIPEVQLVYNSSHFKSLATGGNVSEALALVGEKACYQSISSCGGQIFYLGTKSVHVMTLRSWRERIDHLLKQERLTDALALAWSFYEGKAKAVVGLSGDTSKRKAVIADRMVEILLHYADRTLKKCPDQGKIQVMEQHFQDVVPVIVDYCLLLQRTDLLFNQIYDKMSENSVAKGIFLECLEPYILSDKLMGITAQVMKDLLLHFQDKNRLENMEACIVHMDITSLDIQQVVLLCWENHLYDAMIYVYNSGMNDFISPMEKLLKVIAPPLDAGKSLTDEQVVMGNKLLVYISCCLAGRAYPLGDIPEDLVPLVKNQIFEFLIRLHSTEGSVDEEVYPHIRTLLHFDTREFLNVLALTFEDFKNDKQAVEYQQRIVDILLKVMVENSDFTPSQVGCLFTFLARQLAKPNNTLFVNRTLFDQVLEFLCSPDDDSRHSERQQVLLELLQAGGIVQFEESRLIQMAEKAEFYQICEFMYERELRYDKIIDCYLRDPVRKEEVFNYIHNILSMPGYSAEEKQSVWQKALEHIEELLLLSPCKAADLVAIHFTEQIESIIANLQDQFLLFQFLRSLLDPREGINQDLLHLPPHVTEQFIELLCQHSPEHVLETLKVLEYCRLEETIQITQKHQLHEASSYLLEKKGDIHGAFLVMLERLQSKLLMLTQDDGGSAELPLLESIEDTLMKTIALCQRNSHNLNQQQREALWFPLLEAMMSPQKLSGSSQYRYAESLKSLTMQVLNNMAAFIPLPLILQRILQDPVYGKGKLGEIQGLILGMLDTFNYEQTLLETTTNLLNHDLHWSLCNLRASVTRGLTPKQDYCCICLQQYKRRQESADEIIVFSCGHLYHSLCLLSKECGAVSKDVMRWMCYKCNLSNKGGKLSENFSELKKGSGTSLAQTGSESALDPQQIQAFDQLCRLNRGTSRLALLTELSRAHGGEKHGLLSVSHGDSAASSVFQDETFQLHLAPPPLMDD", "length": 1367, "header": "tr|A0A8V1A5D5-1|A0A8V0ZSS0_CHICK Computationally mapped isoform of Vacuolar protein sorting-associated protein 8 homolog OS=Gallus gallus OX=9031 GN=VPS8 PE=3 SV=1 CANONICAL=A0A8V0ZSS0-1" }, "locus": { "chromosome": "9", "start_pos": 3187111, "end_pos": 3122446, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010059764.1", "url": "https://www.ensembl.org/id/ENSGALT00010059764.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036524.1", "url": "https://www.ensembl.org/id/ENSGALP00010036524.1" } ] } }, { "isoform_ac": "A0A8V1A5E0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSS0/entry#A0A8V1A5E0-1", "sequence": { "sequence": "MDAAPEDGPAGAEAEPDGLPCPEPPAPRLSVAELDRELDSRSELIDDKEFDIPQVDTPPTLESILNETDDEEESFVLEDPFLLNIDNTDTHSYDTSSVASSDSGDRTHLKRKKKLPDSLSLHGSVIRLSLLKGISAQIVSAADKVDAGLPTAIAASNLIAVGTSHGLALIFAADQNQALRLCLGSTAVGAQYGAISALSINNDCSRLLCGFAKGQITMWDLASGKLLRSITDAHPPGTAILHIKFTDDPTLAICNDSGGSVFELSFKRVMGVRTCESRCLFSGSKGEVCCIEPLHAKVELRDHPITQYSLLAMASLTKILVIGLKPSLKVWMTFPYGRMDPSSVPLLAWHFVAVQNSVNPMLAFCRGDVVHFLLVKRDDTGAIHVTKQKQLHLHYDLINFTWINSRTAVLLDSVEKLHVIDRQTQEELETIEIPEVQLVYNSSHFKSLATGGNVSEALALVGEKACYQSISSCGGQIFYLGTKSVHVMTLRSWRERIDHLLKQERLTDALALAWSFYEGKAKAVVGLSGDTSKRKAVIADRMVEILLHYADRTLKKCPDQGKIQVMEQHFQDVVPVIVDYCLLLQRTDLLFNQIYDKMSENSVAKGIFLECLEPYILSDKLMGITAQVMKDLLLHFQDKNRLENMEACIVHMDITSLDIQQVVLLCWENHLYDAMIYVYNSGMNDFISPMEKLLKVIAPPLDAGKSLTDEQVVMGNKLLVYISCCLAGRAYPLGDIPEDLVPLVKNQIFEFLIRLHSTEGSVDEEVYPHIRTLLHFDTREFLNVLALTFEDFKNDKQAVEYQQRIVDILLKVMVENSDFTPSQVGCLFTFLARQLAKPNNTLFVNRTLFDQVLEFLCSPDDDSRHSERQQVLLELLQAGGIVQFEESRLIQMAEKAEFYQICEFMYERELRYDKIIDCYLRDPVRKEEVFNYIHNILSMPGYSAEEKQSVWQKALEHIEELLLLSPCKAADLVAIHFTEQIESIIANLQDQFLLFQFLRSLLDPREGINQDLLHLPPHVTEQFIELLCQHSPEHVLETLKVLEYCRLEETIQITQKHQLHEASSYLLEKKGDIHGAFLVMLERLQSKLLMLTQDDGGSAELPLLESIEDTLMKTIALCQRNSHNLNQQQREALWFPLLEAMMSPQKLSGSSQYRYAESLKSLTMQVLNNMAAFIPLPLILQRILQDPVYGKGKLGEIQGLILGMLDTFNYEQTLLETTTNLLNHDLHWSLCNLRASVTRGLTPKQDYCCICLQQYKRRQESADEIIVFSCGHLYHSLCLLSKECGAVSKDVMRWMCYKCNLSNKGGKLSENFSELKKGSGTSLAQTGSESALDPQQIQAFDQLCRLNRGTSRLALLTELSRAHGGEKHGLLSVSHGDSAASSVFQDETFQLHLAPPPLMDD", "length": 1401, "header": "tr|A0A8V1A5E0-1|A0A8V0ZSS0_CHICK Computationally mapped isoform of Vacuolar protein sorting-associated protein 8 homolog OS=Gallus gallus OX=9031 GN=VPS8 PE=3 SV=1 CANONICAL=A0A8V0ZSS0-1" }, "locus": { "chromosome": "9", "start_pos": 3187111, "end_pos": 3122003, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010059769.1", "url": "https://www.ensembl.org/id/ENSGALT00010059769.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036529.1", "url": "https://www.ensembl.org/id/ENSGALP00010036529.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1331, "start_aa": "Thr", "end_pos": 1331, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1331", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "endosome", "id": "GO:0005768", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005768", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSS0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSS0" } ], "pmid": "" }, { "name": "early endosome", "id": "GO:0005769", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005769", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSS0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSS0" } ], "pmid": "" }, { "name": "late endosome", "id": "GO:0005770", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005770", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSS0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSS0" } ], "pmid": "" }, { "name": "CORVET complex", "id": "GO:0033263", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033263", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSS0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSS0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSS0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSS0" } ], "pmid": "" }, { "name": "protein-membrane adaptor activity", "id": "GO:0043495", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043495", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSS0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSS0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "protein targeting to vacuole", "id": "GO:0006623", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006623", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSS0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSS0" } ], "pmid": "" }, { "name": "endosomal vesicle fusion", "id": "GO:0034058", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034058", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSS0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSS0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1393, "end_pos": 1395, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1404, "end_pos": 1406, "annotation": "n_glycosylation_sequon" }, { "start_pos": 161, "end_pos": 163, "annotation": "n_glycosylation_sequon" }, { "start_pos": 348, "end_pos": 350, "annotation": "n_glycosylation_sequon" }, { "start_pos": 36, "end_pos": 38, "annotation": "n_glycosylation_sequon" }, { "start_pos": 492, "end_pos": 494, "annotation": "n_glycosylation_sequon" }, { "start_pos": 534, "end_pos": 536, "annotation": "n_glycosylation_sequon" }, { "start_pos": 546, "end_pos": 548, "annotation": "n_glycosylation_sequon" }, { "start_pos": 932, "end_pos": 934, "annotation": "n_glycosylation_sequon" }, { "start_pos": 938, "end_pos": 940, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZSS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSS0" }, { "id": "PS50089", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50089" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RING-type", "eco_id": "ECO_0000259", "start_pos": 1341, "end_pos": 1393, "start_aa": "Cys", "end_aa": "Asn", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 1331 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1393, "end_pos": 1395 }, { "start_pos": 1404, "end_pos": 1406 }, { "start_pos": 161, "end_pos": 163 }, { "start_pos": 348, "end_pos": 350 }, { "start_pos": 36, "end_pos": 38 }, { "start_pos": 492, "end_pos": 494 }, { "start_pos": 534, "end_pos": 536 }, { "start_pos": 546, "end_pos": 548 }, { "start_pos": 932, "end_pos": 934 }, { "start_pos": 938, "end_pos": 940 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { 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{ "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZTP8-1", "uniprot_ac": "A0A8V0ZTP8", "uniprot_id": "A0A8V0ZTP8_CHICK", "mass": { "chemical_mass": 44734.0, "monoisotopic_mass": 44734.0 }, "refseq": {}, "gene_names": [ { "name": "TAL1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZTP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTP8" } ] } ], "protein_names": [ { "name": "TAL bHLH transcription factor 1, erythroid differentiation factor", "type": "synonym", "evidence": [ { "id": "A0A8V0ZTP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTP8/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTP8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTP8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TAL1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTP8", "locus": { "chromosome": "8", "start_pos": 21597196, "end_pos": 21605603, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022991", "url": "https://www.ensembl.org/id/ENSGALG00010022991" } ] } } ], "crossref": [ { "id": "A0A8V0ZTP8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZTP8", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd19706", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19706", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "396298", "url": "https://www.ncbi.nlm.nih.gov/gene/396298", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036638", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036638", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040238", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040238", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:396298", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:396298", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MMERQPA", "url": "https://omabrowser.org/oma/group/MMERQPA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZKH4", "url": "https://www.orthodb.org/?gene=A0A8V0ZKH4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZQU8", "url": "https://www.orthodb.org/?gene=A0A8V0ZQU8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZSR7", "url": "https://www.orthodb.org/?gene=A0A8V0ZSR7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZTP8", "url": "https://www.orthodb.org/?gene=A0A8V0ZTP8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13864", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13864", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13864:SF15", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13864:SF15", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00010", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00010", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-8939236", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8939236", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZKH4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKH4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKH4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKH4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQU8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQU8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQU8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQU8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZSR7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSR7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZSR7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSR7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZTP8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTP8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZTP8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTP8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLKINNNYSHTNKVRIAPQWAEMSSKRSGENPRPPSTSLSLWVRCGAGGEGGGGPRVIRTGVQGRGGGGVSAVTSRRRCVTSRRRSGGTPLSGSGRPERCSPRRTMDRPPAPPPPSSDPRDARRHDPEAEPTSEPDSSRGGMEPPAEPQLLLNGAAKEAGRPSPGPPAAAVPVIELVRRGGSLDIKSREAAGEAMQRAPGAEPCRAAEAACEARMVQLSPPALPLQPPGRAMLYNLGQPLGTIGSGFFGEPDSFSMYGSNRVKRRPSPYEMEITDGPHTKVVRRIFTNSRERWRQQNVNGAFAELRKLIPTHPPDKKLSKNEILRLAMKYINFLAKLLNDQEEEGNQRGKVNKDSGIVQEDLLQDMLSPNSSCGSSLDGAASPDSFTEEHDTLDSKHARNLHHTILPVEGSAQR", "length": 414, "header": "tr|A0A8V0ZTP8-1|A0A8V0ZTP8_CHICK Isoform 1 of TAL bHLH transcription factor 1, erythroid differentiation factor OS=Gallus gallus OX=9031 GN=TAL1 PE=4 SV=1 CANONICAL=A0A8V0ZTP8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZKH4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTP8/entry#A0A8V0ZKH4-1", "sequence": { "sequence": "MGRNVLKTETMDRPPAPPPPSSDPRDARRHDPEAEPTSEPDSSRGGMEPPAEPQLLLNGAAKEAGRPSPGPPAAAVPVIELVRRGGSLDIKSREAAGEAMQRAPGAEPCRAAEAACEARMVQLSPPALPLQPPGRAMLYNLGQPLGTIGSGFFGEPDSFSMYGSNRVKRRPSPYEMEITDGPHTKVVRRIFTNSRERWRQQNVNGAFAELRKLIPTHPPDKKLSKNEILRLAMKYINFLAKLLNDQEEEGNQRGKVNKDSGIVQEDLLQDMLSPNSSCGSSLDGAASPDSFTEEHDTLDSKHARNLHHTILPVEGSAQR", "length": 319, "header": "tr|A0A8V0ZKH4-1|A0A8V0ZKH4_CHICK Computationally mapped isoform of TAL bHLH transcription factor 1, erythroid differentiation factor OS=Gallus gallus OX=9031 GN=TAL1 PE=4 SV=1 CANONICAL=A0A8V0ZTP8-1" }, "locus": { "chromosome": "8", "start_pos": 21603522, "end_pos": 21599279, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055964.1", "url": "https://www.ensembl.org/id/ENSGALT00010055964.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033868.1", "url": "https://www.ensembl.org/id/ENSGALP00010033868.1" } ] } }, { "isoform_ac": "A0A8V0ZQU8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTP8/entry#A0A8V0ZQU8-1", "sequence": { "sequence": "MKSKWTMDRPPAPPPPSSDPRDARRHDPEAEPTSEPDSSRGGMEPPAEPQLLLNGAAKEAGRPSPGPPAAAVPVIELVRRGGSLDIKSREAAGEAMQRAPGAEPCRAAEAACEARMVQLSPPALPLQPPGRAMLYNLGQPLGTIGSGFFGEPDSFSMYGSNRVKRRPSPYEMEITDGPHTKVVRRIFTNSRERWRQQNVNGAFAELRKLIPTHPPDKKLSKNEILRLAMKYINFLAKLLNDQEEEGNQRGKVNKDSGIVQEDLLQDMLSPNSSCGSSLDGAASPDSFTEEHDTLDSKHARNLHHTILPVEGSAQR", "length": 315, "header": "tr|A0A8V0ZQU8-1|A0A8V0ZQU8_CHICK Computationally mapped isoform of TAL bHLH transcription factor 1, erythroid differentiation factor OS=Gallus gallus OX=9031 GN=TAL1 PE=4 SV=1 CANONICAL=A0A8V0ZTP8-1" }, "locus": { "chromosome": "8", "start_pos": 21605516, "end_pos": 21599279, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055976.1", "url": "https://www.ensembl.org/id/ENSGALT00010055976.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033875.1", "url": "https://www.ensembl.org/id/ENSGALP00010033875.1" } ] } }, { "isoform_ac": "A0A8V0ZSR7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTP8/entry#A0A8V0ZSR7-1", "sequence": { "sequence": "MTMDRPPAPPPPSSDPRDARRHDPEAEPTSEPDSSRGGMEPPAEPQLLLNGAAKEAGRPSPGPPAAAVPVIELVRRGGSLDIKSREAAGEAMQRAPGAEPCRAAEAACEARMVQLSPPALPLQPPGRAMLYNLGQPLGTIGSGFFGEPDSFSMYGSNRVKRRPSPYEMEITDGPHTKVVRRIFTNSRERWRQQNVNGAFAELRKLIPTHPPDKKLSKNEILRLAMKYINFLAKLLNDQEEEGNQRGKVNKDSGIVQEDLLQDMLSPNSSCGSSLDGAASPDSFTEEHDTLDSKHARNLHHTILPVEGSAQR", "length": 311, "header": "tr|A0A8V0ZSR7-1|A0A8V0ZTP8_CHICK Computationally mapped isoform of TAL bHLH transcription factor 1, erythroid differentiation factor OS=Gallus gallus OX=9031 GN=TAL1 PE=4 SV=1 CANONICAL=A0A8V0ZTP8-1" }, "locus": { "chromosome": "8", "start_pos": 21604150, "end_pos": 21599279, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055979.1", "url": "https://www.ensembl.org/id/ENSGALT00010055979.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033877.1", "url": "https://www.ensembl.org/id/ENSGALP00010033877.1" } ] } }, { "isoform_ac": "A0A8V0ZTP8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTP8/entry#A0A8V0ZTP8-1", "sequence": { "sequence": "MLKINNNYSHTNKVRIAPQWAEMSSKRSGENPRPPSTSLSLWVRCGAGGEGGGGPRVIRTGVQGRGGGGVSAVTSRRRCVTSRRRSGGTPLSGSGRPERCSPRRTMDRPPAPPPPSSDPRDARRHDPEAEPTSEPDSSRGGMEPPAEPQLLLNGAAKEAGRPSPGPPAAAVPVIELVRRGGSLDIKSREAAGEAMQRAPGAEPCRAAEAACEARMVQLSPPALPLQPPGRAMLYNLGQPLGTIGSGFFGEPDSFSMYGSNRVKRRPSPYEMEITDGPHTKVVRRIFTNSRERWRQQNVNGAFAELRKLIPTHPPDKKLSKNEILRLAMKYINFLAKLLNDQEEEGNQRGKVNKDSGIVQEDLLQDMLSPNSSCGSSLDGAASPDSFTEEHDTLDSKHARNLHHTILPVEGSAQR", "length": 414, "header": "tr|A0A8V0ZTP8-1|A0A8V0ZTP8_CHICK Isoform 1 of TAL bHLH transcription factor 1, erythroid differentiation factor OS=Gallus gallus OX=9031 GN=TAL1 PE=4 SV=1 CANONICAL=A0A8V0ZTP8-1" }, "locus": { "chromosome": "8", "start_pos": 21603578, "end_pos": 21599279, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055970.1", "url": "https://www.ensembl.org/id/ENSGALT00010055970.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033871.1", "url": "https://www.ensembl.org/id/ENSGALP00010033871.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:396298", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:396298", "resource": "KEGG Pathway" }, { "id": "R-GGA-8939236", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8939236", "resource": "Reactome", "description": "RUNX1 regulates transcription of genes involved in differentiation of HSCs" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2K1M1-1", "protein_name": "TAL bHLH transcription factor 1, erythroid differentiation factor", "gene_name": "Tal1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTERPPSEAARSDPQLEGQEAAEARMAPPHLVLLNGVTKETNRAAPAETPVIELGARSSAGGGPAGGGGAARDLKGRDAVATEARHRVPTTELCRPPGPAPAPAPASAPAELPGDGRMVQLSPPALAAPAGPGRALLYSLSQPLASLGSGFFGEPDAFPMFTNNNRVKRRPSPYEMEITDGPHTKVVRRIFTNSRERWRQQNVNGAFAELRKLIPTHPPDKKLSKNEILRLAMKYINFLAKLLNDQEEEGTQRAKPGKDPMVGAGGGGAGGGIPPEDLLQDVLSPNSSCGSSLDGAASPDSYTEEPTPKHTPRSLHPALLPAADGAGPR", "length": 329 }, "evidence": [ { "id": "A0A8V0ZTP8", "url": "https://omabrowser.org/oma/group/A0A8V0ZTP8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A286ZXS3-1", "protein_name": "TAL bHLH transcription factor 1, erythroid differentiation factor", "gene_name": "TAL1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTEQPPSEAARSDPPLEGRDAAEARMAPPHLVLLNGVAKETGRAAPAEPPVIELGARGGPGGGPAGGGGAARDLKGRDAAAAAAEARHRVPTTELCRPPGPAPAPASAPAELPGEGRMVQLSPPALAAPAAPGRALLYSLSQPLASLGSGFFGEPDAFPMFATNNRVKRRPSPYEMEITDGPHTKVVRRIFTNSRERWRQQNVNGAFAELRKLIPTHPPDKKLSKNEILRLAMKYINFLAKLLNDQEEEGTQRAKPGKDAVVGAGGGGGGGGGGAPPDDLLQDVLSPNSSCGSSLDGAASPDSYTEEPAPKHTARSLHPAMLPATDGAGPR", "length": 331 }, "evidence": [ { "id": "A0A8V0ZTP8", "url": "https://omabrowser.org/oma/group/A0A8V0ZTP8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "E1BAU0-1", "protein_name": "TAL bHLH transcription factor 1, erythroid differentiation factor", "gene_name": "TAL1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTEQPPSEAAHSDPPLEGRDAAEARMAPPHLVLLNGVAKETSRATPAEPPVIELGTRGGGPGGGPAGGGGAARDLKGREAAAAEARHRVPTTELCRPPGPAPASAPAELPGDGRMVQLSPPALAAPAAPGRALLYSLSQPLASLGSGFFGEPDAFPMFATNNRVKRRPSPYEMEITDGPHTKVVRRIFTNSRERWRQQNVNGAFAELRKLIPTHPPDKKLSKNEILRLAMKYINFLAKLLNDQEEEGTQRAKPGKDPVVGAGGGGGGGGGSAPPEDLLQDVLSPNSSCGSSLDGAASPDSYTEEPAPKHTARSLHPAMLPAADGAGPR", "length": 328 }, "evidence": [ { "id": "A0A8V0ZTP8", "url": "https://omabrowser.org/oma/group/A0A8V0ZTP8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P17542-1", "protein_name": "T-cell acute lymphocytic leukemia protein 1", "gene_name": "TAL1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTERPPSEAARSDPQLEGRDAAEASMAPPHLVLLNGVAKETSRAAAAEPPVIELGARGGPGGGPAGGGGAARDLKGRDAATAEARHRVPTTELCRPPGPAPAPAPASVTAELPGDGRMVQLSPPALAAPAAPGRALLYSLSQPLASLGSGFFGEPDAFPMFTTNNRVKRRPSPYEMEITDGPHTKVVRRIFTNSRERWRQQNVNGAFAELRKLIPTHPPDKKLSKNEILRLAMKYINFLAKLLNDQEEEGTQRAKTGKDPVVGAGGGGGGGGGGAPPDDLLQDVLSPNSSCGSSLDGAASPDSYTEEPAPKHTARSLHPAMLPAADGAGPR", "length": 331 }, "evidence": [ { "id": "A0A8V0ZTP8", "url": "https://omabrowser.org/oma/group/A0A8V0ZTP8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P22091-1", "protein_name": "T-cell acute lymphocytic leukemia protein 1 homolog", "gene_name": "Tal1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTERPPSEAARSDPQLEGQDAAEARMAPPHLVLLNGVAKETSRAAPAEPPVIELGARSGAGGGPASGGGAARDLKGRDAVAAEARLRVPTTELCRPPGPAPAPAPASAPAELPGDGRMVQLSPPALAAPAGPGRALLYSLSQPLASLGSGFFGEPDAFPMFTNNNRVKRRPSPYEMEISDGPHTKVVRRIFTNSRERWRQQNVNGAFAELRKLIPTHPPDKKLSKNEILRLAMKYINFLAKLLNDQEEEGTQRAKPGKDPVVGAGGGGAGGGIPPEDLLQDVLSPNSSCGSSLDGAASPDSYTEEPTPKHTSRSLHPALLPAADGAGPR", "length": 329 }, "evidence": [ { "id": "A0A8V0ZTP8", "url": "https://omabrowser.org/oma/group/A0A8V0ZTP8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTP8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTP8" } ], "pmid": "" }, { "name": "protein dimerization activity", "id": "GO:0046983", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046983", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTP8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTP8" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTP8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTP8" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTP8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTP8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTP8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTP8" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTP8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTP8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 370, "end_pos": 372, "annotation": "n_glycosylation_sequon" }, { "start_pos": 7, "end_pos": 9, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZTP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTP8" }, { "id": "PS50888", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50888" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BHLH", "eco_id": "ECO_0000259", "start_pos": 282, "end_pos": 334, "start_aa": "Val", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 370, "end_pos": 372 }, { "start_pos": 7, "end_pos": 9 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZSS4-1", "uniprot_ac": "A0A8V0ZSS4", "uniprot_id": "A0A8V0ZSS4_CHICK", "mass": { "chemical_mass": 20903.0, "monoisotopic_mass": 20903.0 }, "refseq": {}, "gene_names": [ { "name": "SCT", "type": "recommended", "evidence": [ { "id": "A0A8V0ZSS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSS4" } ] } ], "protein_names": [ { "name": "Secretin", "type": "recommended", "evidence": [ { "id": "A0A8V0ZSS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSS4/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSS4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSS4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SCT", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSS4", "locus": { "chromosome": "5", "start_pos": 764142, "end_pos": 758186, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022996", "url": "https://www.ensembl.org/id/ENSGALG00010022996" } ] } } ], "crossref": [ { "id": "A0A8V0ZSS4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZSS4", "database": "AlphaFoldDB", "categories": [] }, { "id": "423015", "url": "https://www.ncbi.nlm.nih.gov/gene/423015", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000532", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000532", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:423015", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423015", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZQW1", "url": "https://www.orthodb.org/?gene=A0A8V0ZQW1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZSS4", "url": "https://www.orthodb.org/?gene=A0A8V0ZSS4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR17378", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR17378", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR17378:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR17378:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00123", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00123", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZQW1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQW1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQW1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQW1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZSS4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSS4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZSS4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSS4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQWIRGETDISTRVGLFLPLRVGANMVSLMTGLSRLIIPMIVLSHFTASLPSQERTERHADGLFHSELSKMNDNAYVQQLVKHLVGLKERTQRHSDGLFTSEYSKMRGNAQVQKFIQNLMGRKRSSNPSLVKTDVWEKEKENSSEDLCYMWLYQSFLNSSHSDNDAKEAAAVTSQYICPLCSW", "length": 183, "header": "tr|A0A8V0ZSS4-1|A0A8V0ZSS4_CHICK Isoform 1 of Secretin OS=Gallus gallus OX=9031 GN=SCT PE=3 SV=1 CANONICAL=A0A8V0ZSS4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZQW1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSS4/entry#A0A8V0ZQW1-1", "sequence": { "sequence": "MVSLMTGLSRLIIPMIVLSHFTASLPSQERTERHADGLFHSELSKMNDNAYVQQLVKHLVGLKERTQRHSDGLFTSEYSKMRGNAQVQKFIQNLMGRKRSNPSLVKTDVWEKEKENSSEDLCYMWLYQSFLNSSHSDNDAKEAAAVTSQYICPLCSW", "length": 157, "header": "tr|A0A8V0ZQW1-1|A0A8V0ZQW1_CHICK Computationally mapped isoform of Secretin OS=Gallus gallus OX=9031 GN=SCT PE=3 SV=1 CANONICAL=A0A8V0ZSS4-1" }, "locus": { "chromosome": "5", "start_pos": 762778, "end_pos": 760023, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056004.1", "url": "https://www.ensembl.org/id/ENSGALT00010056004.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033890.1", "url": "https://www.ensembl.org/id/ENSGALP00010033890.1" } ] } }, { "isoform_ac": "A0A8V0ZSS4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSS4/entry#A0A8V0ZSS4-1", "sequence": { "sequence": "MQWIRGETDISTRVGLFLPLRVGANMVSLMTGLSRLIIPMIVLSHFTASLPSQERTERHADGLFHSELSKMNDNAYVQQLVKHLVGLKERTQRHSDGLFTSEYSKMRGNAQVQKFIQNLMGRKRSSNPSLVKTDVWEKEKENSSEDLCYMWLYQSFLNSSHSDNDAKEAAAVTSQYICPLCSW", "length": 183, "header": "tr|A0A8V0ZSS4-1|A0A8V0ZSS4_CHICK Isoform 1 of Secretin OS=Gallus gallus OX=9031 GN=SCT PE=3 SV=1 CANONICAL=A0A8V0ZSS4-1" }, "locus": { "chromosome": "5", "start_pos": 762778, "end_pos": 759301, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055999.1", "url": "https://www.ensembl.org/id/ENSGALT00010055999.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033887.1", "url": "https://www.ensembl.org/id/ENSGALP00010033887.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:423015", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423015", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSS4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSS4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "hormone activity", "id": "GO:0005179", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005179", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSS4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSS4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 142, "end_pos": 144, "annotation": "n_glycosylation_sequon" }, { "start_pos": 158, "end_pos": 160, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZSS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSS4" }, { "id": "PS00260", "database": "PROSITE", "url": "https://prosite.expasy.org/PS00260" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Glucagon / GIP / secretin / VIP family", "eco_id": "ECO_0000259", "start_pos": 94, "end_pos": 116, "start_aa": "His", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 142, "end_pos": 144 }, { "start_pos": 158, "end_pos": 160 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZSV0-1", "uniprot_ac": "A0A8V0ZSV0", "uniprot_id": "A0A8V0ZSV0_CHICK", "mass": { "chemical_mass": 58005.0, "monoisotopic_mass": 58005.0 }, "refseq": { "ac": "NP_001025717", "name": "serine beta-lactamase-like protein LACTB, mitochondrial", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025717" }, "gene_names": [ { "name": "LACTB", "type": "recommended", "evidence": [ { "id": "A0A8V0ZSV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSV0" } ] }, { "name": "LACTB", "type": "synonym", "evidence": [ { "id": "NP_001025717", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025717" } ] }, { "name": "mitochondrial", "type": "synonym", "evidence": [ { "id": "NP_001025717", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025717" } ] } ], "protein_names": [ { "name": "Lactamase beta", "type": "synonym", "evidence": [ { "id": "A0A8V0ZSV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSV0/entry#names_and_taxonomy" } ] }, { "name": "serine beta-lactamase-like protein LACTB, mitochondrial", "type": "synonym", "evidence": [ { "id": "NP_001025717", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025717" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ720272.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000245.1. On Sep 23, 2021 this sequence version replaced NP_001025717.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001025717", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025717" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSV0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSV0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LACTB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSV0", "locus": { "chromosome": "10", "start_pos": 4170784, "end_pos": 4180328, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010024517", "url": "https://www.ensembl.org/id/ENSGALG00010024517" } ] } } ], "crossref": [ { "id": "A0A8V0ZSV0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZSV0", "database": "AlphaFoldDB", "categories": [] }, { "id": "415373", "url": "https://www.ncbi.nlm.nih.gov/gene/415373", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001466", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001466", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012338", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012338", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052794", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052794", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:415373", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415373", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CCRQQRH", "url": "https://omabrowser.org/oma/group/CCRQQRH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZSV0", "url": "https://www.orthodb.org/?gene=A0A8V0ZSV0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A5I5", "url": "https://www.orthodb.org/?gene=A0A8V1A5I5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46520", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46520", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46520:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46520:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00144", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00144", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001025717", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025717", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZSV0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSV0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZSV0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSV0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A5I5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5I5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A5I5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5I5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSGLARAVRRVAPVGLAAARHGESGGGRRWGWGLALGLALGVKAAADGGPEEVPQEVPRRGFGAAIERSRDLLRRIKDEAGIPGILVGVSVDGREVWSEGLGYADVENRVMCKPETIMRIASISKCLTMMAVAKLWEEGKLDLDAPVQKYVPEFPEKVYEGEKVTITTRLLVSHLSGIRHYEKDIAKVKEEKEKANRAVKLTKSGQDKEQKEKGGEGIEKTDSVKSKKEHEGEVRSRNSKPGRRDKEFEHEEYYLKEKFESVIESLKIFKNDPLFFKPGSQFLYSTYGFTLLSAVVERVSGQKFTDYMLKMFRDLDMLSTVLDDNEAMIYNRARCYVYNKKGRLVNAPYVDNSYKWAGGGFLSSVGDLLKFGNALLYSYQAGQFRNTDGKLLPGYLKPDTVAMMWTPVPKTEVSWDRDGKYAMAWAVVEKKQQCGFCRRQRHYASHTGGAVGASSVLLILPEELDSGAEDAAVVAPPRGVIVSIICNMQSVSLNSTALKIAREFDKEKRAQYIDSKKRDE", "length": 520, "header": "tr|A0A8V0ZSV0-1|A0A8V0ZSV0_CHICK Isoform 1 of Lactamase beta OS=Gallus gallus OX=9031 GN=LACTB PE=1 SV=1 CANONICAL=A0A8V0ZSV0-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZSV0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSV0/entry#A0A8V0ZSV0-1", "sequence": { "sequence": "MSGLARAVRRVAPVGLAAARHGESGGGRRWGWGLALGLALGVKAAADGGPEEVPQEVPRRGFGAAIERSRDLLRRIKDEAGIPGILVGVSVDGREVWSEGLGYADVENRVMCKPETIMRIASISKCLTMMAVAKLWEEGKLDLDAPVQKYVPEFPEKVYEGEKVTITTRLLVSHLSGIRHYEKDIAKVKEEKEKANRAVKLTKSGQDKEQKEKGGEGIEKTDSVKSKKEHEGEVRSRNSKPGRRDKEFEHEEYYLKEKFESVIESLKIFKNDPLFFKPGSQFLYSTYGFTLLSAVVERVSGQKFTDYMLKMFRDLDMLSTVLDDNEAMIYNRARCYVYNKKGRLVNAPYVDNSYKWAGGGFLSSVGDLLKFGNALLYSYQAGQFRNTDGKLLPGYLKPDTVAMMWTPVPKTEVSWDRDGKYAMAWAVVEKKQQCGFCRRQRHYASHTGGAVGASSVLLILPEELDSGAEDAAVVAPPRGVIVSIICNMQSVSLNSTALKIAREFDKEKRAQYIDSKKRDE", "length": 520, "header": "tr|A0A8V0ZSV0-1|A0A8V0ZSV0_CHICK Isoform 1 of Lactamase beta OS=Gallus gallus OX=9031 GN=LACTB PE=1 SV=1 CANONICAL=A0A8V0ZSV0-1" }, "locus": { "chromosome": "10", "start_pos": 4180319, "end_pos": 4173753, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010059819.1", "url": "https://www.ensembl.org/id/ENSGALT00010059819.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036579.1", "url": "https://www.ensembl.org/id/ENSGALP00010036579.1" } ] } }, { "isoform_ac": "A0A8V1A5I5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSV0/entry#A0A8V1A5I5-1", "sequence": { "sequence": "MSGLARAVRRVAPVGLAAARHGESGGGRRWGWGLALGLALGVKAAADGGPEEVPQEVPRRGFGAAIERSRDLLRRIKVPSVGSPGPGAERPRRGRWERGLGYADVENRVMCKPETIMRIASISKCLTMMAVAKLWEEGKLDLDAPVQKYVPEFPEKVYEGEKVTITTRLLVSHLSGIRHYEKDIAKVKEEKEKANRAVKLTKSGQDKEQKEKGGEGIEKTDSVKSKKEHEGEVRSRNSKPGRRDKEFEHEEYYLKEKFESVIESLKIFKNDPLFFKPGSQFLYSTYGFTLLSAVVERVSGQKFTDYMLKMFRDLDMLSTVLDDNEAMIYNRARCYVYNKKGRLVNAPYVDNSYKWAGGGFLSSVGDLLKFGNALLYSYQAGQFRNTDGKLLPGYLKPDTVAMMWTPVPKTEVSWDRDGKYAMAWAVVEKKQQCGFCRRQRHYASHTGGAVGASSVLLILPEELDSGAEDAAVVAPPRGVIVSIICNMQSVSLNSTALKIAREFDKEKRAQYIDSKKRDE", "length": 519, "header": "tr|A0A8V1A5I5-1|A0A8V0ZSV0_CHICK Computationally mapped isoform of Lactamase beta OS=Gallus gallus OX=9031 GN=LACTB PE=1 SV=1 CANONICAL=A0A8V0ZSV0-1" }, "locus": { "chromosome": "10", "start_pos": 4180319, "end_pos": 4173753, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010059815.1", "url": "https://www.ensembl.org/id/ENSGALT00010059815.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036575.1", "url": "https://www.ensembl.org/id/ENSGALP00010036575.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:415373", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415373", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "B0G0Z7-1", "protein_name": "Beta-lactamase family protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNSLIKGTSLLFVGISGFSTILNCEDKPTTTTKTTTLTNNSVCCKSPTQCIVNSSTLSPIIIKNKKNMNRELKKEILSWKEGNCVPGISVCIQSNGETIYKEAFGFADVENVIPMETSSKLRVASISKALTSIGLGVLFEQGKIKFSDSIQKHVPEWKNSPNFPDDVLTINHVASHLGGIRHYGLNRKAEFYSVEKFKTDKEYNPWGHRNPLEMFKENPWVKDLEKTKPGHYFNYSTFGYTLLGLVIESASGKSFTTFMRDSVFRPCGMFDTQPDEHDSLIPGRSKQYALKFTPRTQQEISANGYDEARVSLCNAEFTNSSYKWPGGGFISTAEDLCKLGSTVLGGRLLKQSTIDHLFKPNPPLTGKNTMNYCTGWFKQPSSKNNTDIIYHTGNAVGGSTVLVMIPQENIVVSVLANQEKTNLINEFGFNLARIASKYNN", "length": 440 }, "evidence": [ { "id": "A0A8V0ZSV0", "url": "https://omabrowser.org/oma/group/A0A8V0ZSV0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "D3ZFJ6-1", "protein_name": "Serine beta-lactamase-like protein LACTB, mitochondrial", "gene_name": "Lactb", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MYRFLSSVTSRATATAGPALGGGRRGAHGRPGLPMLSLGWAGGLGLGLGLALGAKLAIGLRGAVPIQSPADPEASGATELPHEQAPGPGSPHTPASPAARGFSRAIESSRDLLHRIKDEVGAPGIVVGVSVDGKEVWSEGLGYADVENRVPCKPETVMRIASISKSLTMVALAKLWEAGKLDLDLPVQHYVPEFPEKEYEGEKVSVTTRLLISHLSGIRHYEKDMKKVKEEKAYKALKMMKGTPPPDQEKELKEKGGKDNDKSDSPKAKAEQDSEAKCRSAKPGKKKNDFEQGELYLKEKFENSIESLRLFKNDPLFFKPGSQFLYSTFGYTLLAAIVERTSGYKYLDYMQKIFHDLDMLTTVQEENEPVIYNRARFYVYNKKKRLVNTPYVDNSYKWAGGGFLSTVGDLLKFGNAMLYGYQVGLFKNSNENLLPGYLKPETMVMMWTPVPNTEMSWDKEGKYAMAWGVVEKKQTHGACRKQRHYASHTGGAVGASSVLLVLPEELDPEAVNNKVPPRGIIVSIICNMQSVGLNSTALKIALEFDKDRAD", "length": 550 }, "evidence": [ { "id": "A0A8V0ZSV0", "url": "https://omabrowser.org/oma/group/A0A8V0ZSV0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1S089-1", "protein_name": "Serine beta-lactamase-like protein LACTB, mitochondrial", "gene_name": "LACTB", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MYRLLSAVPARAATPRGCAWGCGRRAAHQRAGLPKLGPGWVGGLGLGLGLALGMKLAGGLRGASPAPPPAAPDPESPILSEPLPPQEQPLAPWSPHTPVPPHARRFARAIDSSRDLLHRIKDEVGAPGIVVGVSVDGKEVWSEGLGYADVENRVPCKPETVMRIASISKSLTMVALAKLWEAGKLDLDIPVQHYVPEFPEKEYEGEKVSVTTRLLISHLSGIRHYEKDMKKVKEEKAYKALKMMKETESDQEKDLKEKGGKSNEKNDFAAKTKIEQDNEAKSRNSKPCKKKNDFEQGELYLKEKFENSIESLRLFKNDPLFFKPGSQFLYSTFGYTLLAAIVERASGYKYLDYMQKIFHDLDMLTTVQEENEPVIYNRARFYVYNKKKRLVNTPYVDNSYKWAGGGFLSTVGDLLKFGNAMLYGYQVGLFKNSNENLLPGYLKPETMLMIWTPVPNTEMSWDKEGKYAMAWGVVEKKQTYGSCRKQRHYASHTGGAVGASSVLLVLPEELDAEALNNKVPPRGIVVSIICNMQSVGLNSTALKIALEFDKDRSDIP", "length": 556 }, "evidence": [ { "id": "A0A8V0ZSV0", "url": "https://omabrowser.org/oma/group/A0A8V0ZSV0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P83111-1", "protein_name": "Serine beta-lactamase-like protein LACTB, mitochondrial", "gene_name": "LACTB", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MYRLMSAVTARAAAPGGLASSCGRRGVHQRAGLPPLGHGWVGGLGLGLGLALGVKLAGGLRGAAPAQSPAAPDPEASPLAEPPQEQSLAPWSPQTPAPPCSRCFARAIESSRDLLHRIKDEVGAPGIVVGVSVDGKEVWSEGLGYADVENRVPCKPETVMRIASISKSLTMVALAKLWEAGKLDLDIPVQHYVPEFPEKEYEGEKVSVTTRLLISHLSGIRHYEKDIKKVKEEKAYKALKMMKENVAFEQEKEGKSNEKNDFTKFKTEQENEAKCRNSKPGKKKNDFEQGELYLREKFENSIESLRLFKNDPLFFKPGSQFLYSTFGYTLLAAIVERASGCKYLDYMQKIFHDLDMLTTVQEENEPVIYNRARFYVYNKKKRLVNTPYVDNSYKWAGGGFLSTVGDLLKFGNAMLYGYQVGLFKNSNENLLPGYLKPETMVMMWTPVPNTEMSWDKEGKYAMAWGVVERKQTYGSCRKQRHYASHTGGAVGASSVLLVLPEELDTETINNKVPPRGIIVSIICNMQSVGLNSTALKIALEFDKDRSD", "length": 547 }, "evidence": [ { "id": "A0A8V0ZSV0", "url": "https://omabrowser.org/oma/group/A0A8V0ZSV0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9EP89-1", "protein_name": "Serine beta-lactamase-like protein LACTB, mitochondrial", "gene_name": "Lactb", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MYRLLSSVTARAAATAGPAWDGGRRGAHRRPGLPVLGLGWAGGLGLGLGLALGAKLVVGLRGAVPIQSPADPEASGTTELSHEQALSPGSPHTPAPPAARGFSRAIESSRDLLHRIKDEVGAPGIVVGVSVDGKEVWSEGLGYADVENRVPCKPETVMRIASISKSLTMVALAKLWEAGKLDLDLPVQHYVPEFPEKEYEGEKVSVTTRLLISHLSGIRHYEKDIKKVKEEKAYKALKMVKGTPPPSDQEKELKEKGGKNNEKSDAPKAKVEQDSEARCRSAKPGKKKNDFEQGELYLKEKFENSIESLRLFKNDPLFFKPGSQFLYSTFGYTLLAAIVERASGYKYLDYMQKIFHDLDMLTTVQEENEPVIYNRARFYVYNKKKRLVNTPYVDNSYKWAGGGFLSTVGDLLKFGNAMLYGYQVGQFKNSNENLLPGYLKPETMVMMWTPVPNTEMSWDKEGKYAMAWGVVEKKQTYGSCRKQRHYASHTGGAVGASSVLLVLPEELDSEAVNNKVPPRGIIVSIICNMQSVGLNSTALKIALEFDKDRAD", "length": 551 }, "evidence": [ { "id": "A0A8V0ZSV0", "url": "https://omabrowser.org/oma/group/A0A8V0ZSV0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSV0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSV0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSV0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSV0" } ], "pmid": "" }, { "name": "regulation of lipid metabolic process", "id": "GO:0019216", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019216", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSV0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSV0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "peptidase activity", "id": "GO:0008233", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008233", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSV0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSV0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 494, "end_pos": 496, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZSV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSV0" }, { "id": "PF00144", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00144" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Beta-lactamase-related", "eco_id": "ECO_0000259", "start_pos": 71, "end_pos": 189, "start_aa": "Asp", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 494, "end_pos": 496 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZSV6-1", "uniprot_ac": "A0A8V0ZSV6", "uniprot_id": "A0A8V0ZSV6_CHICK", "mass": { "chemical_mass": 42980.0, "monoisotopic_mass": 42980.0 }, "refseq": { "ac": "XP_046756023", "name": "coiled-coil domain-containing protein 71", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046756023" }, "gene_names": [ { "name": "CCDC71", "type": "recommended", "evidence": [ { "id": "A0A8V0ZSV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSV6" } ] }, { "name": "CCDC71", "type": "synonym", "evidence": [ { "id": "XP_046756023", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046756023" } ] } ], "protein_names": [ { "name": "Coiled-coil domain containing 71", "type": "synonym", "evidence": [ { "id": "A0A8V0ZSV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSV6/entry#names_and_taxonomy" } ] }, { "name": "coiled-coil domain-containing protein 71", "type": "synonym", "evidence": [ { "id": "XP_046756023", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046756023" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052543.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_046756023", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046756023" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSV6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSV6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CCDC71", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSV6", "locus": { "chromosome": "12", "start_pos": 11730294, "end_pos": 11720026, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021785", "url": "https://www.ensembl.org/id/ENSGALG00010021785" } ] } } ], "crossref": [ { "id": "100858691", "url": "https://www.ncbi.nlm.nih.gov/gene/100858691", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026695", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026695", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:100858691", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100858691", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CPETVGQ", "url": "https://omabrowser.org/oma/group/CPETVGQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZSV6", "url": "https://www.orthodb.org/?gene=A0A8V0ZSV6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14484", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14484", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14484:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14484:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15374", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15374", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_046756023", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046756023", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZSV6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSV6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZSV6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSV6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNIAVNNVEEKAVHSWSRIYSAGQKVLEEALRVFNPMSKDLSDTETQLVAFIQGLKEEGFQPTILRSKDVYGYSSCTADTPSQAKGSTPHSCAAATTSTPPKTPARSTVAMARASASPTSISVNSSKVSSPPVSKGDSTNLLLNSFKQTRSGKSKASVVGFPASMYPDVYPAVRLSVVLEALVPLKTPTSCLDSKYRRGPLGVSSSDLKLLKVSSQTRQFSSGKTTKIREGKRCKRVGKKAPHSATLALNLLKGLKAGVLQESNACKASGVLNGRIAGSSSQGCTTAAQSKALKIKAKEAPVGKMEWKDSSTYQETVGKKRKRVAEVRDAPQRKKSKSIPVQNKSRRARSTLNLLKFWAIKVGNSSSDDEVRRRAQKILRVNLSPVIRIQPLSHSHSVP", "length": 399, "header": "tr|A0A8V0ZSV6-1|A0A8V0ZSV6_CHICK Isoform 1 of Coiled-coil domain containing 71 OS=Gallus gallus OX=9031 GN=CCDC71 PE=4 SV=1 CANONICAL=A0A8V0ZSV6-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZSV6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSV6/entry#A0A8V0ZSV6-1", "sequence": { "sequence": "MNIAVNNVEEKAVHSWSRIYSAGQKVLEEALRVFNPMSKDLSDTETQLVAFIQGLKEEGFQPTILRSKDVYGYSSCTADTPSQAKGSTPHSCAAATTSTPPKTPARSTVAMARASASPTSISVNSSKVSSPPVSKGDSTNLLLNSFKQTRSGKSKASVVGFPASMYPDVYPAVRLSVVLEALVPLKTPTSCLDSKYRRGPLGVSSSDLKLLKVSSQTRQFSSGKTTKIREGKRCKRVGKKAPHSATLALNLLKGLKAGVLQESNACKASGVLNGRIAGSSSQGCTTAAQSKALKIKAKEAPVGKMEWKDSSTYQETVGKKRKRVAEVRDAPQRKKSKSIPVQNKSRRARSTLNLLKFWAIKVGNSSSDDEVRRRAQKILRVNLSPVIRIQPLSHSHSVP", "length": 399, "header": "tr|A0A8V0ZSV6-1|A0A8V0ZSV6_CHICK Isoform 1 of Coiled-coil domain containing 71 OS=Gallus gallus OX=9031 GN=CCDC71 PE=4 SV=1 CANONICAL=A0A8V0ZSV6-1" }, "locus": { "chromosome": "12", "start_pos": 11728886, "end_pos": 11728106, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052985.1", "url": "https://www.ensembl.org/id/ENSGALT00010052985.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031891.1", "url": "https://www.ensembl.org/id/ENSGALP00010031891.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:100858691", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100858691", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1SPT4-1", "protein_name": "Coiled-coil domain containing 71", "gene_name": "CCDC71", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSVVVQHVEEKAVHSWSRISTAGKKALEEALLVFNPMSQDLSATEAQLVAFLQGLRDDGFQPTILRSGDVYGYSSCTANPPSQTKLQARAPMPAATSPPASAPRTPMQLSAGQATLLPMPLSGRLAKASTPPLTKHATTNLLLNSLKQSSASHAQGAAVGFPTHLYPGVYPAMRLSVVLEALVPLKTPIPCLSAKHKAQSVQLSLADSPLKLRRGPGKSPGNSQPKVPRKATSKGPKGLTQRGSRAGPRQGNGPQNKTYKATGSLSSPRMKGGCSLGTKIAQAKAARAQAKVARTQAKVAKARAKAKAAQIKAKAKAARARAKAKAKAVQAKAKAKAARARARAKSKAVRANAKAVQAKAKVARIQPRGRGRPKRSVQARTARKGQKRCPETVGQKRKRADEEKDLPPRKRTRLGPQSPKMWLGRGTAKLLRFQAIKVDRRSSDDEVRQQAQQILHVNLSPIIQLQPLLP", "length": 470 }, "evidence": [ { "id": "A0A8V0ZSV6", "url": "https://omabrowser.org/oma/group/A0A8V0ZSV6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q2HJ91-1", "protein_name": "Coiled-coil domain-containing protein 71", "gene_name": "CCDC71", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSVVVQHVEEKAVHSWSRISTAGKKALEEALLVFNPMSQDLSATEAQLVAFLQGLRDDGFQPTILRSGDVYGYSSCTANPPSQTKLQARAPTPAATSPPASAPQTAVRLPAGRATLLPMPLSGRLAKASTPGLAKHATTNLLLSSLKQSSAGRAQGAAVGFPTHLYPGVYPAMRLSVVLEALVPIKTPVACLGAKPKAQSLQLSLGDSPLKVRKGPGKRLGNAQLKAPRKATSKGSKCLAQRGPRSGPRQGAGLQSKTCKVTGSLGGPRVKDGGALGTKAAQAKAACAQAKVAQTQATATQARAKAKAVRARAKAKAARIKAREVRARAKAKAVQAKAKVARTQPRGRGRPKGSIQGRTARRSRKSRPETVGQKRKRTEEAKDLSPRKRTRLGPRSPKVQLGPGTARLLKFRAIKVDRLASDDEVRQQAQRILRVNLSPVIRLQPLPPHSAP", "length": 452 }, "evidence": [ { "id": "A0A8V0ZSV6", "url": "https://omabrowser.org/oma/group/A0A8V0ZSV6/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q4V7C4-1", "protein_name": "Coiled-coil domain-containing protein 71", "gene_name": "Ccdc71", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSMVVQHVEEKAVHSWSRISTAGKKALEEALLVFNPMSQDLSATEAQLVAFLQGLRDDGFQPTILRSGDVYGYSSCTASPPSQTKLQARTINPPATSLPARAPQTAKSVPTGQTTLLPVPLSGRLAKGSTPALAKHTTTNLLLSSLKQSNASNTSGTTVGFPAHLYPGVYPAMQLSVVLEALVPLKTPCLDVKHRAQSLQLSLAKSSLKLRKGSGNPQSKAPRRITSKGLKYLTSKGPGAGLRRGAGTQSNGARMKGRSTLGTKTVRGKAPRTLTKAVCARASVAPAKTKTVRVRAKVKQAKPKAAKAKAKAAALRGKAKDKAVQAKAKAARTKHKKRPKGYVQTRTGRTSLKNSSETVGQKRKKAEETKGLPPKKRARCVPRSKARLGTGTAKPQKSQTIKVDRKCSDDEVRQCAQQILRVNLSPVVLLQPLLPV", "length": 436 }, "evidence": [ { "id": "A0A8V0ZSV6", "url": "https://omabrowser.org/oma/group/A0A8V0ZSV6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8IV32-1", "protein_name": "Coiled-coil domain-containing protein 71", "gene_name": "CCDC71", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSVVVQHVEEKAVHSWSRISTAGKKALEEALLVFNPMSQDLSATEAQLVAFLQGLRDDGFQPTILRSGDVYGYSSCTANPPSQTKLQARAPNPTATSPPASAPRTAMRLPAGRATLLPMPLSGRLAKASTPALAKHATTNLLLSSLKQSSASHARGAAVGFPTHLYPGVYPAMRLSVVLEALVPLKTPMPCLGAKHKAQSLQLSLADSPLKLRKSSGKGPGNPRPKAPRKTTSKGPKCLTRKGPGAGPRRGSGHQSKTNRATGSPSVRRMKGGSALGTKTAQAKVARTLAKAARAQAKVARTQAKAAKARAKAKAAQVKAKAKAKAAQVKAKAKVMAAWAKAKAKAKAVRAKAKVARTQPRGRGRPKGSAKARTTRKGQKNRPETVGQKRKRAEEAKDLPPKKRTRLGPRSPKAWLGPGTAKLLKFRAIKVDRRSSDDEVRQRAQRILRVNLSPVIRLQPLLPYSAV", "length": 467 }, "evidence": [ { "id": "A0A8V0ZSV6", "url": "https://omabrowser.org/oma/group/A0A8V0ZSV6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8VEG0-1", "protein_name": "Coiled-coil domain-containing protein 71", "gene_name": "Ccdc71", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSMVVQPVEEKAVHSWSRISTAGKKALEEALLVFNPMSQDLSATEAQLVAFLQGLRDDGFQPTILRSGDVYGYSSCTASPPSQTKLQARTINPPATSLPKTAVSVPAGRTTLLPVPLSGRLAKGSTAALAKHATTNLLLSSLKQSSASNSSGTTVGFPAHLYPGVYPAMRLSVVLEALVPLKTPCLDVKHGAQSLQLSLAKSPLKVRKASGNPKSKAPRKITSKGLKHLTSKGPGAGLRRGAGTQSNGAQRKGCSALGPKTVQAQASQTLIKAARAHASVAQTQTKTVRVRAKAKQAKPKAARAKAKAAVVRDKAKDKVIQAKAKAAQTKHKGKPKGSVQTRTGRANRKNSSETVGRKRKKAEETKGLPPKKRARCVPRPPKVWLGPGTAKPRKSQTIKVDRKCSDDEVRQCAQQILRVNLSPVVWLQPLLPF", "length": 433 }, "evidence": [ { "id": "A0A8V0ZSV6", "url": "https://omabrowser.org/oma/group/A0A8V0ZSV6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 124, "end_pos": 126, "annotation": "n_glycosylation_sequon" }, { "start_pos": 343, "end_pos": 345, "annotation": "n_glycosylation_sequon" }, { "start_pos": 364, "end_pos": 366, "annotation": "n_glycosylation_sequon" }, { "start_pos": 382, "end_pos": 384, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 124, "end_pos": 126 }, { "start_pos": 343, "end_pos": 345 }, { "start_pos": 364, "end_pos": 366 }, { "start_pos": 382, "end_pos": 384 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZSW0-1", "uniprot_ac": "A0A8V0ZSW0", "uniprot_id": "A0A8V0ZSW0_CHICK", "mass": { "chemical_mass": 188398.0, "monoisotopic_mass": 188398.0 }, "refseq": { "ac": "XP_040557626", "name": "PHD and RING finger domain-containing protein 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040557626" }, "gene_names": [ { "name": "PHRF1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZSW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSW0" } ] }, { "name": "PHRF1", "type": "synonym", "evidence": [ { "id": "XP_040557626", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040557626" } ] } ], "protein_names": [ { "name": "PHD and RING finger domain-containing protein 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_040557626", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040557626" } ] }, { "name": "PHD and ring finger domains 1", "type": "synonym", "evidence": [ { "id": "A0A8V0ZSW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSW0/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052536.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040557626", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040557626" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSW0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSW0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PHRF1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSW0", "locus": { "chromosome": "5", "start_pos": 15455069, "end_pos": 15480219, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010023026", "url": "https://www.ensembl.org/id/ENSGALG00010023026" } ] } } ], "crossref": [ { "id": "cd15536", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15536", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd16635", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16635", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "426102", "url": "https://www.ncbi.nlm.nih.gov/gene/426102", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001965", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001965", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011011", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011011", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017907", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017907", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019786", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019786", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019787", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019787", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047157", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047157", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057031", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057031", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "VENTRAC", "url": "https://omabrowser.org/oma/group/VENTRAC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZSW0", "url": "https://www.orthodb.org/?gene=A0A8V0ZSW0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12618", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12618", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12618:SF20", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12618:SF20", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00628", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00628", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13639", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13639", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23030", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23030", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040557626", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040557626", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZSW0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSW0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZSW0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSW0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDDDSQDELINKNAALGKGKKQSLALLSETESNGGNSCESEGDTGSEEEEDDTEEEGGEEDKEESEDEELEDCEDDDEEEEEEEAEAAVGGTANPLKLKPHVNGVNVSSDEDGENCPICLNTFRDQAVGTPENCSHYFCLDCIVEWSKNANSCPVDRILFKYISIRAHFGGKVLKKIPVENTKTQGSEGEDDPTFCEVCGRSDREDRLLLCDGCDAGYHMECLNPPLSEVPVDEWFCPACVPMGVSASADTDHVSEEEVAALVADVTPTTSRLRPHVRTRAIARTRQSERVRATVNRNRITTAQQIQHVPRYLMSSLLDETIEAVVAGLNTAIYQHPLTLRAPARQKRKTGRRRKAAGKKRTQTKSSAGKKTSGTQVKRRKRLMKKRRGKKIRIRSRVKNEVTARSRIARTLGLSKPVRGASLPSMYKPTEPSLGLMRADIGAASLSVFGDPYELDPYEGNEEVPANPDSPLSAKRRVLSQSALRSHRPVARPVSVGLPRSSVPALSPDQEAEAAPVPDLLGSILSGQSILMMSSSDVVINRDGSLTAKKAAPLHRKSVKDTRMDDGSGHNPQLSMVHSGTMTGSSIAGPSVSSGLNTHARPTSSSLFSLPSPSRPEPAANPAQTTSEKATVKSEYSVTPKSVQTRSVPSLNRPGSKSDEMPRFNGNSKNFARTDSSSKPLSCNLNSGSKAVTVRQPLKPPPRRIDIFELPRIPKIKKETSSKQVDSEPTGSQSCDIPSSCITQLTGKESTNQLGKGSKMESQKSNARETQQQTRTSGVSFSTSAGMYSSSSLLGTSRSKGSSSFESFKINIPGNTGHSSRLSNPGFCNTFRPVDDKVQQKESPSALFSVKKKQVKSEIYDPFEPTGSDSSSASSSPERLGSGIPLTNITRTISIENPKVQTFQTVRRFTPYTVENIFGSGAESDVPSSNTESHDDVPAESRIVEQISDTEERDNMDEEDFLSSPCTSSVVKQVSNTEHLKEEGREGPSVFFNAEELIRPNINVKLEPDSSSKNDGQQKVPKTEQTERRSRSRSCSNSSSRSRKKAKRKKALAKERKRSRSGSRGRAHSRDRSSRSTSWSGGEDSSKIHTLKSKSRRSSTDRSSSHERSKKKKTKDKTKDKKAKSSWSKEKRKSRSRSGSPGSTSEFYENRKKKRRSRSRSRRRGRSRSNSIERTKRRKHRRDKSYERYDKDSSLRSRDRKRSRSRSREKRKWRSRSRSASRSQEHKSSKSKEKRPRSRSRSKERKRKSKETSLPSPPEKEQKPPAENVPSCPEQSHSFKQEPKDELVLEQLSISIQPNVKLEEIQAETPVQQREAQETAKAEATCEEVASETAFPVPEITNVCVPVGNVASFAETELMNTSDPGLLGSCSNTNLEITVKIENTALCPPLMEPPPKKEVMMHAQTEAVPVQSSSQTADCVREVKDECLVSNEKASNFSQPELEVVSQGPVLKSKAPVKRVTWNLQEEESGVLSAGRAPRMPFYKLQRAKEGAWKAEDLNQTLNQVQLNEPPPTNYMIPEPMFPDLDSSQVYCQNIPLTPPLPSSLPPYAPVSQPTVQFIMQGSLPALGCVAGQSLTPEPGSLATASEPGNQAASVGNEEEKIKAPKPEVDKTKNEEYMKKLHMQERAVEEVKLAIKPFYQKREITKEEYKNILRKAVQKICHSKSGEINPVKVANLVKAYVEKYKHMRKHKKSDVEDAREMEN", "length": 1703, "header": "tr|A0A8V0ZSW0-1|A0A8V0ZSW0_CHICK Isoform 1 of PHD and ring finger domains 1 OS=Gallus gallus OX=9031 GN=PHRF1 PE=4 SV=1 CANONICAL=A0A8V0ZSW0-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZSW0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSW0/entry#A0A8V0ZSW0-1", "sequence": { "sequence": "MDDDSQDELINKNAALGKGKKQSLALLSETESNGGNSCESEGDTGSEEEEDDTEEEGGEEDKEESEDEELEDCEDDDEEEEEEEAEAAVGGTANPLKLKPHVNGVNVSSDEDGENCPICLNTFRDQAVGTPENCSHYFCLDCIVEWSKNANSCPVDRILFKYISIRAHFGGKVLKKIPVENTKTQGSEGEDDPTFCEVCGRSDREDRLLLCDGCDAGYHMECLNPPLSEVPVDEWFCPACVPMGVSASADTDHVSEEEVAALVADVTPTTSRLRPHVRTRAIARTRQSERVRATVNRNRITTAQQIQHVPRYLMSSLLDETIEAVVAGLNTAIYQHPLTLRAPARQKRKTGRRRKAAGKKRTQTKSSAGKKTSGTQVKRRKRLMKKRRGKKIRIRSRVKNEVTARSRIARTLGLSKPVRGASLPSMYKPTEPSLGLMRADIGAASLSVFGDPYELDPYEGNEEVPANPDSPLSAKRRVLSQSALRSHRPVARPVSVGLPRSSVPALSPDQEAEAAPVPDLLGSILSGQSILMMSSSDVVINRDGSLTAKKAAPLHRKSVKDTRMDDGSGHNPQLSMVHSGTMTGSSIAGPSVSSGLNTHARPTSSSLFSLPSPSRPEPAANPAQTTSEKATVKSEYSVTPKSVQTRSVPSLNRPGSKSDEMPRFNGNSKNFARTDSSSKPLSCNLNSGSKAVTVRQPLKPPPRRIDIFELPRIPKIKKETSSKQVDSEPTGSQSCDIPSSCITQLTGKESTNQLGKGSKMESQKSNARETQQQTRTSGVSFSTSAGMYSSSSLLGTSRSKGSSSFESFKINIPGNTGHSSRLSNPGFCNTFRPVDDKVQQKESPSALFSVKKKQVKSEIYDPFEPTGSDSSSASSSPERLGSGIPLTNITRTISIENPKVQTFQTVRRFTPYTVENIFGSGAESDVPSSNTESHDDVPAESRIVEQISDTEERDNMDEEDFLSSPCTSSVVKQVSNTEHLKEEGREGPSVFFNAEELIRPNINVKLEPDSSSKNDGQQKVPKTEQTERRSRSRSCSNSSSRSRKKAKRKKALAKERKRSRSGSRGRAHSRDRSSRSTSWSGGEDSSKIHTLKSKSRRSSTDRSSSHERSKKKKTKDKTKDKKAKSSWSKEKRKSRSRSGSPGSTSEFYENRKKKRRSRSRSRRRGRSRSNSIERTKRRKHRRDKSYERYDKDSSLRSRDRKRSRSRSREKRKWRSRSRSASRSQEHKSSKSKEKRPRSRSRSKERKRKSKETSLPSPPEKEQKPPAENVPSCPEQSHSFKQEPKDELVLEQLSISIQPNVKLEEIQAETPVQQREAQETAKAEATCEEVASETAFPVPEITNVCVPVGNVASFAETELMNTSDPGLLGSCSNTNLEITVKIENTALCPPLMEPPPKKEVMMHAQTEAVPVQSSSQTADCVREVKDECLVSNEKASNFSQPELEVVSQGPVLKSKAPVKRVTWNLQEEESGVLSAGRAPRMPFYKLQRAKEGAWKAEDLNQTLNQVQLNEPPPTNYMIPEPMFPDLDSSQVYCQNIPLTPPLPSSLPPYAPVSQPTVQFIMQGSLPALGCVAGQSLTPEPGSLATASEPGNQAASVGNEEEKIKAPKPEVDKTKNEEYMKKLHMQERAVEEVKLAIKPFYQKREITKEEYKNILRKAVQKICHSKSGEINPVKVANLVKAYVEKYKHMRKHKKSDVEDAREMEN", "length": 1703, "header": "tr|A0A8V0ZSW0-1|A0A8V0ZSW0_CHICK Isoform 1 of PHD and ring finger domains 1 OS=Gallus gallus OX=9031 GN=PHRF1 PE=4 SV=1 CANONICAL=A0A8V0ZSW0-1" }, "locus": { "chromosome": "5", "start_pos": 15476796, "end_pos": 15456073, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056070.1", "url": "https://www.ensembl.org/id/ENSGALT00010056070.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033922.1", "url": "https://www.ensembl.org/id/ENSGALP00010033922.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A6H619-1", "protein_name": "PHD and RING finger domain-containing protein 1", "gene_name": "Phrf1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDDDNLDELVAHSPGPDGPPRVGSSELASDAEESSNGQSGDSEDDTGSEQDDDTDGEETEGLSEEEDPEDRSGSEDSEDGVEMATAAIETQGKLEASSVPNSDDDAESCPICLNAFRDQAVGTPETCAHYFCLDCIIEWSRNANSCPVDRTVFKCICIRAQFNGKILKKIPVENTKACEAEEEDPTFCEVCGRSDREDRLLLCDGCDAGYHMECLDPPLQEVPVDEWFCPECTVPGVDPTHDAAPVSDEEVSLLLADVVPTTSRLRPRVGRTRAIARTRQSERVRATVNRNRISSARRVQHVPRYLMSSLLDETIEAVATGLSTAVYQRPLTPRVPAKRKRKAGRRKKVLGRKKTRSRSSVKSKSGSTRAKKRQHRVRKTKGRKLKNEVTARSRIARTLGLRRPVRGTSMPSVYKPVDPSLGLMRADIGAASLSLFGDPYELDPFDSNEEQSADPPSPLSAKRRVLSRSALQSHQPVARPVAMGLSRRQLPAVAPEPSVEEAPVPDLLGSILSGQSLLMMSSADVVIHRDGSLSAKRAAPVSLQRNSVTQSREESRLRDNPQPGALPSESASGGFVGDRQPNSGLSCGNRTALCCLPARIAQTPVRSDPSLTPRSGLSRTLSDENRPSRTHSSSPQLNGSNVRVSSASTKIVTHSSFPSKNTASGLPQRTGPRRPDFSKLPRIPKIHRDGNKSTQDQAPASGHIVELPSTCISRLTGREGPGQPGRGRVDSEPSSRGPQETGSHTSGSRPPAPSSHGSLAHLGPSRGKGIGSSFESFRINIPGNTAHCSQLSSPGFCNTFRPVDSKVQRKETPFPLFSIKKPKQLKSEIYDPFDPTGSDSSPPSSSPESLGPGLLPSEITRTISINSPKAPAFQTVRCVTSYRVESIFGTEMEPEPQPPSEPVSGMLELLSKGSAEGTSDLEQEGLGEIEPTEIRGSTARTQRPPPPDPWDDEDEVSCTPFFGSEERTVTCVTVEEPGVLPSPDAPQITTHRIVEFRASSRSRSTSSSRSRKKTKKKKKKVAREHQRTRSSTRSGSRDRTSRSVSPVAEEHTRRHRAKTKSRRSSSDRASSQDRAKRRKDRDDRDREHRRGSWGHGRCRRKSRSRSGSPGSSSCERHESKRRKRRHSGSRSRGSSLERDRRHKHRERSRERMDKQESVTRSRERRRWRSRSPSLEHRPRRPPSREKRAHSPEKKGPVREVSPAPATQGESRQDGDHSAEPPVSEVSVLPEVVSVLPEVVVADLNPPEVPPVLAEPVAHVPEDLDYGESVEAGHVFEDFSNEAIFIQLDDMSSPPSPESTDSSPERDFPPNPILPPASLPQDSTLPTIQREVLPIHSEDISKPVPQALAPSDQSLLKQDTVEITTTTPSTPAVVPMTKDSPVLSARGWEAVRPRDAVAQAPLLRSRTLVKRVTWNLQEAEHSTPAALDRDPRTPLQRPQRPQEGDWDAEDRALIGFQQAPFSELPPPIHVLQESGLPDADPSQPPGAPRAEGLPAAGTLHSAGGILAQVYSPNMPPPLAQPSSILPYALVSQPSVQLILQGTLPLAGCGTAQSLAPVPTMPATVSELAVPTTNNSEERTATPKTAAEKTKKEEYMKKLHMQERAVEEVKLAIKPFYQKREVTKEEYKDILRKAVQKICHSKSGEINPVKVANLVKAYVDKYRHMRRHKKTEGGEEPPTQGAET", "length": 1682 }, "evidence": [ { "id": "A0A8V0ZSW0", "url": "https://omabrowser.org/oma/group/A0A8V0ZSW0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q63625-1", "protein_name": "PHD and RING finger domain-containing protein 1", "gene_name": "Phrf1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDDDNLDELVAHSPGPDGPPQVGSSELASDAEESSNGHSEDSEDDTGSEQDDDTDGEETEGLSEEEDPEDRSGSEDSEDGIEVPTAAVETQRKLEASSTPNSDDDAESCPICLNAFRDQAVGTPETCAHYFCLDCIIEWSRNANSCPVDRTIFKCICIRAQFNGKILKKIPVENTRACEDEEAEEEDPTFCEVCGRSDREDRLLLCDGCDAGYHMECLDPPLQEVPVDEWFCPECAVPGVDPTHDAAPVSDEEVSLLLADVVPTTSRLRPRVGRTRAIARTRQSERVRATVNRNRISSARRVQHVPRYLMSSLLDETIEAVATGLSTAVYQRPLTPRVPAKRKRKAGRRKKVLGRKKTRSRSSVKSKSGGTRAKKRQHRVRRTKGRKLKNEVTARSRIARTLGLRRPVRGTSMPSVYKPVDPSLGLMRADIGAASLSLFGDPYALDPFDSNGEQSADPPSPLSAKRRVLSRSALQSHQPVARPVAMGLARRQLPAVAPEPSVEEAPVPDLLGSILCGQSLLMMSSADVVIHRDGSLSAKRAAPVSLQRNSVTQSREESRLRDNLQPGALPSESVSGGLIGDRRPNSGLSCGDRTALRCLPAQIVQTPVRSDSSVTPRSGLSGNLSDESRPKWKHSNSPRLNGSNVRVGSASTKTMTHSNFPSKNIAPGHPQKTDPRRPDFSKLPRIPKIRRDGSNSTQDQAPASGQTVELPSACISRLTGREGPGQPGRGRADSEPSSRGPQETGSHTSGSRPPAPSSHGNLAPLGPSRGKGIGSSFESFRINIPGNTAHCSQLSSPGFCNTFRPVDSKVQRKENPSPLFSIKKPKQLKSEIYDPFDPTGSDSSPPSSSPESLGSGLLPSEITRTISINSPKAPAFQTVRCVTSYRVESVFGTEMDPDPQPPGEPVSGMLELLGKGPAEGASDLEQEGLGEIEPTEIQGSSARAQRPSPPDPWDDEDGVSCTPFFGSEERTVTCVTVEEPSVPSPDAPQITTHRIVEFRASSRSRSTSSSRSRKKTKKKKKVAREHQRTRSSTRSGSRDRTSRSVSPFTEEHTKRHRAKTKSRRSSSDRASSQDRAKRRKDRDREHRRGPWGHGRCWRKSRSRSGSPGSSSCERHESRRRKRRHSGSRSRGRDGSPHSSLERDRRHKHRERSRERMDKKESMTRSRERRRWRSRSPSVEHRTRRPHSREKHPHSPEKKGAVREVSPAPAPQGEPRQDGDHSTKPPVSEVSVLPEVVSVLPEVVVADLNPPEVPPVLAESVSCVPEDLDYGDSVEAGHVFEDFSNEAIFIQLDDMSSPPSPESTDSSPERDFLPNPILPPASLPQNSTLPVTQREVLPIHSEDISKPAPQPLAPSDQCLLRQDTVETTATTLSTPGVLPMGKDSPLLSGRGCEVVRPKDAVAPAPLLRSRTLVKRVTWNLQEAEASTPALDRDPRTPLQRPQRPQEGDWDAEDRALIGFQQAPFSELPPPIHVLQESGLPDADPSQPPGVPRAEGPPAVGTLHSAGGILAQVYSPNMPPPLAQPSSIPPYALVNQPSVQLILQGTLPLASCGAAQNLAPVPTMPATASELAVPTTNNSEERTATPKTAAEKTKKEEYMKKLHMQERAVEEVKLAIKPFYQKREVTKEEYKDILRKAVQKICHSKSGEINPVKVANLVKAYVDKYRHMRKHKKTEAGEEPPTQGAET", "length": 1685 }, "evidence": [ { "id": "A0A8V0ZSW0", "url": "https://omabrowser.org/oma/group/A0A8V0ZSW0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9P1Y6-1", "protein_name": "PHD and RING finger domain-containing protein 1", "gene_name": "PHRF1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDDDSLDELVARSPGPDGHPQVGPADPAGDFEESSVGSSGDSGDDSDSEHGDGTDGEDEGASEEEDLEDRSGSEDSEDDGETLLEVAGTQGKLEAAGSFNSDDDAESCPICLNAFRDQAVGTPENCAHYFCLDCIVEWSKNANSCPVDRTLFKCICIRAQFGGKILRKIPVENTKASEEEEDPTFCEVCGRSDREDRLLLCDGCDAGYHMECLDPPLQEVPVDEWFCPECAAPGVVLAADAGPVSEEEVSLLLADVVPTTSRLRPRAGRTRAIARTRQSERVRATVNRNRISTARRVQHTPGRLGSSLLDEAIEAVATGLSTAVYQRPLTPRTPARRKRKTRRRKKVPGRKKTPSGPSAKSKSSATRSKKRQHRVKKRRGKKVKSEATTRSRIARTLGLRRPVHSSCIPSVLKPVEPSLGLLRADIGAASLSLFGDPYELDPFDSSEELSANPLSPLSAKRRALSRSALQSHQPVARPVSVGLSRRRLPAAVPEPDLEEEPVPDLLGSILSGQSLLMLGSSDVIIHRDGSLSAKRAAPVSFQRNSGSLSRGEEGFKGCLQPRALPSGSPAQGPSGNRPQSTGLSCQGRSRTPARTAGAPVRLDLPAAPGAVQARNLSNGSVPGFRQSHSPWFNGTNKHTLPLASAASKISSRDSKPPCRSVVPGPPLKPAPRRTDISELPRIPKIRRDDGGGRRDAAPAHGQSIEIPSACISRLTGREGTGQPGRGTRAESEASSRVPREPGVHTGSSRPPAPSSHGSLAPLGPSRGKGVGSTFESFRINIPGNMAHSSQLSSPGFCNTFRPVDDKEQRKENPSPLFSIKKTKQLRSEVYDPSDPTGSDSSAPGSSPERSGPGLLPSEITRTISINSPKAQTVQAVRCVTSYTVESIFGTEPEPPLGPSSAMSKLRGAVAAEGASDTEREEPTESQGLAARLRRPSPPEPWDEEDGASCSTFFGSEERTVTCVTVVEPEAPPSPDVLQAATHRVVELRPPSRSRSTSSSRSRKKAKRKRVSREHGRTRSGTRSESRDRSSRSASPSVGEERPRRQRSKAKSRRSSSDRSSSRERAKRKKAKDKSREHRRGPWGHSRRTSRSRSGSPGSSSYEHYESRKKKKRRSASRPRGRECSPTSSLERLCRHKHQRERSHERPDRKESVAWPRDRRKRRSRSPSSEHRAREHRRPRSREKWPQTRSHSPERKGAVREASPAPLAQGEPGREDLPTRLPALGEAHVSPEVATADKAPLQAPPVLEVAAECEPDDLDLDYGDSVEAGHVFDDFSSDAVFIQLDDMSSPPSPESTDSSPERDFPLKPALPPASLAVAAIQREVSLMHDEDPSQPPPLPEGTQEPHLLRPDAAEKAEAPSSPDVAPAGKEDSPSASGRVQEAARPEEVVSQTPLLRSRALVKRVTWNLQESESSAPAEDRAPRAPLHRPQKPREGAWDMEDVAPTGVRQVFSELPFPSHVLPEPGFPDTDPSQVYSPGLPPAPAQPSSIPPCALVSQPTVQFILQGSLPLVGCGAAQTLAPVPAALTPASEPASQATAASNSEEKTPAPRLAAEKTKKEEYMKKLHMQERAVEEVKLAIKPFYQKREVTKEEYKDILRKAVQKICHSKSGEINPVKVANLVKAYVDKYRHMRRHKKPEAGEEPPTQGAEG", "length": 1649 }, "evidence": [ { "id": "A0A8V0ZSW0", "url": "https://omabrowser.org/oma/group/A0A8V0ZSW0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSW0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSW0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1037, "end_pos": 1039, "annotation": "n_glycosylation_sequon" }, { "start_pos": 106, "end_pos": 108, "annotation": "n_glycosylation_sequon" }, { "start_pos": 133, "end_pos": 135, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1360, "end_pos": 1362, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1436, "end_pos": 1438, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1499, "end_pos": 1501, "annotation": "n_glycosylation_sequon" }, { "start_pos": 888, "end_pos": 890, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZSW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSW0" }, { "id": "PS50016", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50016" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PHD-type", "eco_id": "ECO_0000259", "start_pos": 193, "end_pos": 243, "start_aa": "Pro", "end_aa": "Met", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZSW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSW0" }, { "id": "PS50089", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50089" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RING-type", "eco_id": "ECO_0000259", "start_pos": 116, "end_pos": 157, "start_aa": "Cys", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1037, "end_pos": 1039 }, { "start_pos": 106, "end_pos": 108 }, { "start_pos": 133, "end_pos": 135 }, { "start_pos": 1360, "end_pos": 1362 }, { "start_pos": 1436, "end_pos": 1438 }, { "start_pos": 1499, "end_pos": 1501 }, { "start_pos": 888, "end_pos": 890 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZSX9-1", "uniprot_ac": "A0A8V0ZSX9", "uniprot_id": "A0A8V0ZSX9_CHICK", "mass": { "chemical_mass": 57202.0, "monoisotopic_mass": 57202.0 }, "refseq": { "ac": "XP_015147915", "name": "unconventional prefoldin RPB5 interactor 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015147915" }, "gene_names": [ { "name": "URI1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZSX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSX9" } ] }, { "name": "URI1", "type": "synonym", "evidence": [ { "id": "XP_015147915", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015147915" } ] } ], "protein_names": [ { "name": "Protein phosphatase 1 regulatory subunit 19", "type": "recommended", "evidence": [ { "id": "A0A8V0ZSX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSX9/entry#names_and_taxonomy" } ] }, { "name": "RNA polymerase II subunit 5-mediating protein", "type": "synonym", "evidence": [ { "id": "A0A8V0ZSX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSX9/entry#names_and_taxonomy" } ] }, { "name": "unconventional prefoldin RPB5 interactor 1", "type": "synonym", "evidence": [ { "id": "XP_015147915", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015147915" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052542.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015147915.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015147915", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015147915" } ] }, { "annotation": "Plays a central role in maintaining S6K1 signaling and BAD phosphorylation under normal growth conditions thereby protecting cells from potential deleterious effects of sustained S6K1 signaling. The URI1-PPP1CC complex acts as a central component of a negative feedback mechanism that counteracts excessive S6K1 survival signaling to BAD in response to growth factors. Mediates inhibition of PPP1CC phosphatase activity in mitochondria. Coordinates the regulation of nutrient-sensitive gene expression availability in a mTOR-dependent manner. Seems to be a scaffolding protein able to assemble a prefoldin-like complex that contains PFDs and proteins with roles in transcription and ubiquitination.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSX9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSX9#function" }, { "database": "UniProtKB", "id": "ARBA00053952", "url": "https://www.uniprot.org/uniprotkb/ARBA00053952#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSX9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSX9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "URI1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSX9", "locus": { "chromosome": "11", "start_pos": 8188791, "end_pos": 8148444, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010024536", "url": "https://www.ensembl.org/id/ENSGALG00010024536" } ] } } ], "crossref": [ { "id": "A0A8V0ZSX9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZSX9", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd23159", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd23159", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "415759", "url": "https://www.ncbi.nlm.nih.gov/gene/415759", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004127", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004127", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009053", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009053", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052255", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052255", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:415759", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415759", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HWKKVDD", "url": "https://omabrowser.org/oma/group/HWKKVDD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZSX9", "url": "https://www.orthodb.org/?gene=A0A8V0ZSX9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15111", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15111", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15111:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15111:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02996", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02996", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015147915", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015147915", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZSX9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSX9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZSX9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSX9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEAPGGASPLSPALVGRLRQEHEKVVTTCQEKIQHWKKVESDYEVLQERLRTLPDKLSYDIMVPFGPLAFMPGKLVNTNEVTVLLGDNWFSKCSAKQAVELVEHRKKYVRKAVDDLQKVMKNFESRVEFTEDLQKMSDAAGDFVDIREEIKDDSIETKGKYRTAHKPHSKPKVSDAFEVDFLANGRDTKSVGRFQSEEELWARLEELERQEEILGELDRMPDTVETNGEDTTSSEEEKEDKRMDLNGTYRVEDCITQGNFQKEVTNSDLFVRHVNGSTYYHSDDEDDTDVGDSSVPTIFFSHTVEPKRVRINTGKNTTLKFSEKKEEAKRKRKNSNGNGHGHATPELPNIKTPADIYRVFVDVVNGEYVPRKSILKSRSRENSVCSDTSENSAAEFDDRRGVQRSISCDEATQSDNSEGILEEEEEVGQQQLPKKLPASSGTTEAFSGTVIEKEPLSPSLIPHPVIAHPVLPTILEQKSEEVLSKASEETTKRISKFKAARMQQTN", "length": 506, "header": "tr|A0A8V0ZSX9-1|A0A8V0ZSX9_CHICK Isoform 1 of Protein phosphatase 1 regulatory subunit 19 OS=Gallus gallus OX=9031 GN=URI1 PE=3 SV=1 CANONICAL=A0A8V0ZSX9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZSX9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSX9/entry#A0A8V0ZSX9-1", "sequence": { "sequence": "MEAPGGASPLSPALVGRLRQEHEKVVTTCQEKIQHWKKVESDYEVLQERLRTLPDKLSYDIMVPFGPLAFMPGKLVNTNEVTVLLGDNWFSKCSAKQAVELVEHRKKYVRKAVDDLQKVMKNFESRVEFTEDLQKMSDAAGDFVDIREEIKDDSIETKGKYRTAHKPHSKPKVSDAFEVDFLANGRDTKSVGRFQSEEELWARLEELERQEEILGELDRMPDTVETNGEDTTSSEEEKEDKRMDLNGTYRVEDCITQGNFQKEVTNSDLFVRHVNGSTYYHSDDEDDTDVGDSSVPTIFFSHTVEPKRVRINTGKNTTLKFSEKKEEAKRKRKNSNGNGHGHATPELPNIKTPADIYRVFVDVVNGEYVPRKSILKSRSRENSVCSDTSENSAAEFDDRRGVQRSISCDEATQSDNSEGILEEEEEVGQQQLPKKLPASSGTTEAFSGTVIEKEPLSPSLIPHPVIAHPVLPTILEQKSEEVLSKASEETTKRISKFKAARMQQTN", "length": 506, "header": "tr|A0A8V0ZSX9-1|A0A8V0ZSX9_CHICK Isoform 1 of Protein phosphatase 1 regulatory subunit 19 OS=Gallus gallus OX=9031 GN=URI1 PE=3 SV=1 CANONICAL=A0A8V0ZSX9-1" }, "locus": { "chromosome": "11", "start_pos": 8188169, "end_pos": 8148807, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010059849.1", "url": "https://www.ensembl.org/id/ENSGALT00010059849.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036609.1", "url": "https://www.ensembl.org/id/ENSGALP00010036609.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:415759", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415759", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0ABK0M3M5-1", "protein_name": "Protein NNX3", "gene_name": "Uri1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEDFLCQLGFSFSDLAWGILETPIPSTYRKSHILDMTRLRDEADPRISSLVSLSLCSPSTMKERSRSPLTPITMMFILSRAKHTWVEPSETESVVTNCQEKIQHWEKVDNDYSALQERLRTLPDKLSYDIMVPFGPLAFMPGKLVHTNEVTVLLGDNWFAKCSAKQAVGLVEHRKEHVRKTIDDFKKVLKNFESRVEFTEDLQKMSDAAGDFVDIREEIKSDFEFKGKQRIAHKPHSKPKTSDIFEAEFENGIKPQGTFDDDELWARLEELERQEELLGELKSKPDTVIANGEDTVSSEEEKEDEDTGVNVVSPVTDSSAPSSCKRHGGNAGLPNGQTSSLNYSVNGSNSYHSNKEDEEEEEEEDEDDDEEDDDDESDHAVSADNSIPTIYFSHTVEPKRVRINTGKNTTLKFSEKKEEAKRKRKSGAASHSAHELPAIRSPADIYRVFVDVVNGEYIPRKSILKSRSRENSVCSDTSESSAADVDIDRRAPLRSPSSEETEAGSSTLEELQENHPKKPLPSGVSEAFSGTVIEKEFLSPSLAPHSAIAHHALPTIPERKEVLSEASEEPAKRVSKFRAARLQQRN", "length": 586 }, "evidence": [ { "id": "A0A8V0ZSX9", "url": "https://omabrowser.org/oma/group/A0A8V0ZSX9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O94763-1", "protein_name": "Unconventional prefoldin RPB5 interactor 1", "gene_name": "URI1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEAPTVETPPDPSPPSAPAPALVPLRAPDVARLREEQEKVVTNCQERIQHWKKVDNDYNALRERLSTLPDKLSYNIMVPFGPFAFMPGKLVHTNEVTVLLGDNWFAKCSAKQAVGLVEHRKEHVRKTIDDLKKVMKNFESRVEFTEDLQKMSDAAGDIVDIREEIKCDFEFKAKHRIAHKPHSKPKTSDIFEADIANDVKSKDLLADKELWARLEELERQEELLGELDSKPDTVIANGEDTTSSEEEKEDRNTNVNAMHQVTDSHTPCHKDVASSEPFSGQVNSQLNCSVNGSSSYHSDDDDDDDDDDDDDNIDDDDGDNDHEALGVGDNSIPTIYFSHTVEPKRVRINTGKNTTLKFSEKKEEAKRKRKNSTGSGHSAQELPTIRTPADIYRAFVDVVNGEYVPRKSILKSRSRENSVCSDTSESSAAEFDDRRGVLRSISCEEATCSDTSESILEEEPQENQKKLLPLSVTPEAFSGTVIEKEFVSPSLTPPPAIAHPALPTIPERKEVLLEASEETGKRVSKFKAARLQQKD", "length": 535 }, "evidence": [ { "id": "A0A8V0ZSX9", "url": "https://omabrowser.org/oma/group/A0A8V0ZSX9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q3TLD5-1", "protein_name": "Unconventional prefoldin RPB5 interactor", "gene_name": "Uri1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEPPSEPEPEPQPLAEASAAAPLRAPEVARLREEQEKVVTNCQEKIQHWEKVDNDYSALQERLRTLPDKLSYDVMVPFGPLAFMPGKLVHTNEVTVLLGDNWFAKCSAKQAVGLVEHRKEHVRKTIDDFKKVLKNFESRVEFTEDLQKMSDAAGDFVDIREEIKSDFEFKGKQRIAHKPHSKPKTSDIFEADFENGVKPKNTFDADELWARLEELERQEELLGELESKPDTVIANGEDRVSSEEEKEGADTGVNVVSPVTDSSAASSCKRRAGNAGLPNGQVNSLNYSVNGSNSYHSNKDDDEEEEDDDDDDDEDDDNESDHAISADNSIPTIYFSHTVEPKRVRINTGKNTTLKFSEKKEEAKRKRKSGAGSHATHELPAIKSPADIYRVFVDVVNGEYVPRKSILKSRSRENSVCSDTSESSAADVEDRRGLLRSTSSEEAVATEAGGSSLDELQENHPKKPLPSGVSEAFSGTVIEKEFLSPSLAPYSAIAHHALPTIPERKEVPSEVSEEPTKRVSKFRAARLQQRS", "length": 531 }, "evidence": [ { "id": "A0A8V0ZSX9", "url": "https://omabrowser.org/oma/group/A0A8V0ZSX9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 8, "go_terms": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSX9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSX9" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSX9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSX9" } ], "pmid": "" }, { "name": "response to virus", "id": "GO:0009615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009615", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSX9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSX9" } ], "pmid": "" }, { "name": "intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator", "id": "GO:0042771", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042771", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSX9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSX9" } ], "pmid": "" }, { "name": "cellular response to growth factor stimulus", "id": "GO:0071363", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071363", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSX9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSX9" } ], "pmid": "" }, { "name": "regulation of cell growth", "id": "GO:0001558", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001558", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSX9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSX9" } ], "pmid": "" }, { "name": "cellular response to steroid hormone stimulus", "id": "GO:0071383", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071383", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSX9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSX9" } ], "pmid": "" }, { "name": "negative regulation of intrinsic apoptotic signaling pathway", "id": "GO:2001243", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2001243", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSX9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSX9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSX9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSX9" } ], "pmid": "" }, { "name": "transcription corepressor activity", "id": "GO:0003714", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003714", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSX9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSX9" } ], "pmid": "" }, { "name": "phosphoprotein binding", "id": "GO:0051219", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051219", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSX9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSX9" } ], "pmid": "" }, { "name": "phosphatase inhibitor activity", "id": "GO:0019212", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019212", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSX9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSX9" } ], "pmid": "" }, { "name": "RNA polymerase II complex binding", "id": "GO:0000993", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000993", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSX9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSX9" } ], "pmid": "" }, { "name": "protein phosphatase inhibitor activity", "id": "GO:0004864", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004864", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSX9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSX9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSX9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSX9" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSX9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSX9" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSX9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSX9" } ], "pmid": "" }, { "name": "dendrite", "id": "GO:0030425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSX9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSX9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 246, "end_pos": 248, "annotation": "n_glycosylation_sequon" }, { "start_pos": 275, "end_pos": 277, "annotation": "n_glycosylation_sequon" }, { "start_pos": 316, "end_pos": 318, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 246, "end_pos": 248 }, { "start_pos": 275, "end_pos": 277 }, { "start_pos": 316, "end_pos": 318 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZSY5-1", "uniprot_ac": "A0A8V0ZSY5", "uniprot_id": "A0A8V0ZSY5_CHICK", "mass": { "chemical_mass": 112234.0, "monoisotopic_mass": 112234.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Bromodomain testis-specific protein", "type": "recommended", "evidence": [ { "id": "A0A8V0ZSY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSY5/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSY5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSY5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSY5", "locus": {} } ], "crossref": [ { "id": "A0A8V0ZSY5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZSY5", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd05497", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05497", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001487", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001487", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018359", "url": 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"length": 997, "header": "tr|A0A8V0ZSY5-1|A0A8V0ZSY5_CHICK Isoform 1 of Bromodomain testis-specific protein OS=Gallus gallus OX=9031 GN= PE=3 SV=1 CANONICAL=A0A8V0ZSY5-1" }, "locus": { "chromosome": "8", "start_pos": 14047838, "end_pos": 14029066, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010059854.1", "url": "https://www.ensembl.org/id/ENSGALT00010059854.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036614.1", "url": "https://www.ensembl.org/id/ENSGALP00010036614.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSY5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSY5" } ], "pmid": "" }, { "name": 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} ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSY5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSY5" } ], "pmid": "" }, { "name": "regulation of RNA splicing", "id": "GO:0043484", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043484", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSY5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSY5" } ], "pmid": "" }, { "name": "male meiosis I", "id": "GO:0007141", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007141", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSY5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSY5" } ], "pmid": "" }, { "name": "sperm DNA condensation", "id": "GO:0035092", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035092", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSY5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSY5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "histone binding", "id": "GO:0042393", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042393", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSY5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSY5" } ], "pmid": "" }, { "name": "histone reader activity", "id": "GO:0140566", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140566", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSY5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSY5" } ], "pmid": "" }, { "name": "histone H4 reader activity", "id": "GO:0140008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140008", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSY5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSY5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 47, "end_pos": 49, "annotation": "n_glycosylation_sequon" }, { "start_pos": 561, "end_pos": 563, "annotation": 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"A0A8V0ZT03", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT03" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "oxidoreductase activity", "id": "GO:0016491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016491", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZT03", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT03" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 39, "end_pos": 41, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZT03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT03" }, { "id": "SM00822", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00822" } ], "ann_type": "Domain_Extent_Annotation", 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{ "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZT22-1", "uniprot_ac": "A0A8V0ZT22", "uniprot_id": "A0A8V0ZT22_CHICK", "mass": { "chemical_mass": 46828.0, "monoisotopic_mass": 46828.0 }, "refseq": {}, "gene_names": [ { "name": "SUDS3", "type": "recommended", "evidence": [ { "id": "A0A8V0ZT22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT22" } ] } ], "protein_names": [ { "name": "SDS3 homolog, SIN3A corepressor complex component", "type": "synonym", 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complex component OS=Gallus gallus OX=9031 GN=SUDS3 PE=1 SV=1 CANONICAL=A0A8V0ZT22-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZT22-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT22/entry#A0A8V0ZT22-1", "sequence": { "sequence": "MRDAVPGPRTGDPSATHRALRPHPIRPPVRCPPRSPAAPRVHPAVVRAAGSGSGARVLALLPERPAEPRLVFSRPAAMSAAGLVSATPPAPAPPGAPTPAMPPGPEYYEEEELESAEEEDGERSARARDSDEDTEDASETDLAKHEEEDFVEMKEQMYQDKLASLKRQLQQLQEGTLQEYQKRMKKLDQQYKERIRNAELFLQLETDQVEKNYVKEKKAAAKEFEDKKIELKENLIAELEEKKKMIENEKLTMELTGDSMEVKPIMTRKLRRRPNDPVPIPDKRRKPAPAQLNYLLTDEQIMEDLRTLNKLKSPKRPASPSSPEHLPATPAESPAQRFEARIEDGKLYYDKRWYHKSQAIYLESKENTKISCVISSVGANEIWVRKTSDSTKMRIYLGQLQRGVFVIRRRSAA", "length": 413, "header": "tr|A0A8V0ZT22-1|A0A8V0ZT22_CHICK Isoform 1 of SDS3 homolog, SIN3A corepressor complex component OS=Gallus gallus OX=9031 GN=SUDS3 PE=1 SV=1 CANONICAL=A0A8V0ZT22-1" }, "locus": { "chromosome": "15", "start_pos": 9822490, "end_pos": 9801231, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": 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"Reactome", "description": "Ub-specific processing proteases" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZT22", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT22" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZT22", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT22" } ], "pmid": "" }, { "name": "regulation of gene expression", "id": "GO:0010468", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010468", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZT22", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT22" } ], "pmid": "" } ] }, { "name": "Molecular Function", 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"url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT22" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZT22", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT22" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 98 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": 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"count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZT30-1", "uniprot_ac": "A0A8V0ZT30", "uniprot_id": "A0A8V0ZT30_CHICK", "mass": { "chemical_mass": 68062.0, "monoisotopic_mass": 68062.0 }, "refseq": { "ac": "XP_004949984", "name": "ankyrin repeat domain-containing protein 13A isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004949984" }, "gene_names": [ { "name": "ANKRD13A", "type": "recommended", "evidence": [ { "id": "A0A8V0ZT30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT30" } ] }, { "name": "ANKRD13A", "type": "synonym", "evidence": [ { "id": "XP_004949984", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004949984" } ] } ], "protein_names": [ { "name": "Ankyrin repeat domain 13A", "type": "synonym", "evidence": [ { "id": "A0A8V0ZT30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT30/entry#names_and_taxonomy" } ] }, { "name": "ankyrin repeat domain-containing protein 13A isoform X2", "type": "synonym", "evidence": [ { "id": "XP_004949984", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004949984" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052546.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004949984", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004949984" } ] }, { "annotation": "Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Does not bind 'Lys-48'-linked ubiquitin. Positively regulates the internalization of ligand-activated EGFR by binding to the Ub moiety of ubiquitinated EGFR at the cell membrane.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZT30", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT30#function" }, { "database": "UniProtKB", "id": "ARBA00024956", "url": "https://www.uniprot.org/uniprotkb/ARBA00024956#function" }, { "database": "UniProtKB", "id": "A0A8V0ZMP3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMP3#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZT30", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT30" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ANKRD13A", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT30", "locus": { "chromosome": "15", "start_pos": 6909139, "end_pos": 6896227, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021810", "url": "https://www.ensembl.org/id/ENSGALG00010021810" } ] } } ], "crossref": [ { "id": "A0A8V0ZT30", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZT30", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000043357", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000043357", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "416902", "url": "https://www.ncbi.nlm.nih.gov/gene/416902", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003903", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003903", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021832", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021832", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055285", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055285", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416902", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416902", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CHENGLG", "url": "https://omabrowser.org/oma/group/CHENGLG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PWU4", "url": "https://www.orthodb.org/?gene=A0A1D5PWU4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZMP3", "url": "https://www.orthodb.org/?gene=A0A8V0ZMP3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZT30", "url": "https://www.orthodb.org/?gene=A0A8V0ZT30", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12447", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12447", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12447:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12447:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF11904", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11904", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12796", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12796", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004949984", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004949984", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PWU4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PWU4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PWU4-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PWU4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMP3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMP3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMP3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMP3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZT30", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT30", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZT30-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT30-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAEPAGGTPRMASDAFPLHVLVWNNEYRRLDEELQDQDVDQRDPRGRTLLHLAVSLGYIESAKVLLQHKADVTKENAQGWTVLHEAISTGDPEMVHMILQHRDYQQTSRTLGGVPELLQKINETPDFYVEMKWEFTSWVPLVSRVCPSDVCRIWKSGAKLRVDITLLGFENMSWERGRRSLIFKGEDAEGWAELIEINHDDKFVTTERFEISQHMERLTLGSMTPKRREVERRLTTPIINTCLDTKSIAFERTTSGFWVWRTEKAEGVNGYEAKVYMANNVNVVTKIRTEHLTEEEKKRYKADRSPLESFLGTVEHEYGVQSAVKTTEYATSNNPTAITPEEYFDPEFDLKGRDIGRPKEVTIRTQKFKATLWMSEEFPLSLVEQVTPIIDLMARTSAHFARLRDFITLEFPPGFPVKIEIPLFHVLNARITFENVNSCRTAERTSQTVGSAQGDSGANFEVDQSVFEIPKSYHVQDDGRNIHVHDEDNEIMQFAIQQSLLESSGNKEVGAHSNGAVAYSQDFNIQYQRALQESYLTSTGNSQCSSPSEPSSFEKDLQLAMELSVREQEERERQRREEEDAELQQVLQLSLVEK", "length": 594, "header": "tr|A0A8V0ZT30-1|A0A8V0ZT30_CHICK Isoform 1 of Ankyrin repeat domain 13A OS=Gallus gallus OX=9031 GN=ANKRD13A PE=1 SV=1 CANONICAL=A0A8V0ZT30-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PWU4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT30/entry#A0A1D5PWU4-1", "sequence": { "sequence": "MVHMILQHRDYQQTSRTLGGVPELLQKINETPDFYVEMKWEFTSWVPLVSRVCPSDVCRIWKSGAKLRVDITLLGFENMSWERGRRSLIFKGEDAEGWAELIEINHDDKFVTTERFEISQHMERLTLGSMTPKRREVERRLTTPIINTCLDTKSIAFERTTSGFWVWRTEKAEGVNGYEAKVYMANNVNVVTKIRTEHLTEEEKKRYKADRSPLESFLGTVEHEYGVQSAVKTTEYATSNNPTAITPEEYFDPEFDLKGRDIGRPKEVTIRTQKFKATLWMSEEFPLSLVEQVTPIIDLMARTSAHFARLRDFITLEFPPGFPVKIEIPLFHVLNARITFENVNSCRTAERTSQTVGSAQGDSGANFEVDQSVFEIPKSYHVQDDGRNIHVHDEDNEIMQFAIQQSLLESSGNKEVGAHSNGAVAYSQDFNIQYQRALQESYLTSTGNSQCSSPSEPSSFEKDLQLAMELSVREQEERERQRREEEDAELQQVLQLSLVEK", "length": 501, "header": "tr|A0A1D5PWU4-1|A0A1D5PWU4_CHICK Computationally mapped isoform of Ankyrin repeat domain 13A OS=Gallus gallus OX=9031 GN=ANKRD13A PE=1 SV=3 CANONICAL=A0A8V0ZT30-1" }, "locus": { "chromosome": "15", "start_pos": 6906855, "end_pos": 6899590, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053064.1", "url": "https://www.ensembl.org/id/ENSGALT00010053064.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031959.1", "url": "https://www.ensembl.org/id/ENSGALP00010031959.1" } ] } }, { "isoform_ac": "A0A8V0ZMP3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT30/entry#A0A8V0ZMP3-1", "sequence": { "sequence": "MMSSPGRASDAFPLHVLVWNNEYRRLDEELQDQDVDQRDPRGRTLLHLAVSLGYIESAKVLLQHKADVTKENAQGWTVLHEAISTGDPEMVHMILQHRDYQQTSRTLGGVPELLQKINETPDFYVEMKWEFTSWVPLVSRVCPSDVCRIWKSGAKLRVDITLLGFENMSWERGRRSLIFKGEDAEGWAELIEINHDDKFVTTERFEISQHMERLTLGSMTPKRREVERRLTTPIINTCLDTKSIAFERTTSGFWVWRTEKAEGVNGYEAKVYMANNVNVVTKIRTEHLTEEEKKRYKADRSPLESFLGTVEHEYVKTTEYATSNNPTAITPEEYFDPEFDLKGRDIGRPKEVTIRTQKFKATLWMSEEFPLSLVEQVTPIIDLMARTSAHFARLRDFITLEFPPGFPVKIEIPLFHVLNARITFENVNSCRTAERTSQTVGSAQGDSGANFEVDQSVFEIPKSYHVQDDGRNIHVHDEDNEIMQFAIQQSLLESSGNKEVGAHSNGAVAYSQDFNIQYQRALQESYLTSTGNSQCSSPSEPSSFEKDLQLAMELSVREQEERERQRREEEDAELQQVLQLSLVEK", "length": 585, "header": "tr|A0A8V0ZMP3-1|A0A8V0ZMP3_CHICK Computationally mapped isoform of Ankyrin repeat domain 13A OS=Gallus gallus OX=9031 GN=ANKRD13A PE=1 SV=1 CANONICAL=A0A8V0ZT30-1" }, "locus": { "chromosome": "15", "start_pos": 6906855, "end_pos": 6897133, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053070.1", "url": "https://www.ensembl.org/id/ENSGALT00010053070.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031964.1", "url": "https://www.ensembl.org/id/ENSGALP00010031964.1" } ] } }, { "isoform_ac": "A0A8V0ZT30-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT30/entry#A0A8V0ZT30-1", "sequence": { "sequence": "MAEPAGGTPRMASDAFPLHVLVWNNEYRRLDEELQDQDVDQRDPRGRTLLHLAVSLGYIESAKVLLQHKADVTKENAQGWTVLHEAISTGDPEMVHMILQHRDYQQTSRTLGGVPELLQKINETPDFYVEMKWEFTSWVPLVSRVCPSDVCRIWKSGAKLRVDITLLGFENMSWERGRRSLIFKGEDAEGWAELIEINHDDKFVTTERFEISQHMERLTLGSMTPKRREVERRLTTPIINTCLDTKSIAFERTTSGFWVWRTEKAEGVNGYEAKVYMANNVNVVTKIRTEHLTEEEKKRYKADRSPLESFLGTVEHEYGVQSAVKTTEYATSNNPTAITPEEYFDPEFDLKGRDIGRPKEVTIRTQKFKATLWMSEEFPLSLVEQVTPIIDLMARTSAHFARLRDFITLEFPPGFPVKIEIPLFHVLNARITFENVNSCRTAERTSQTVGSAQGDSGANFEVDQSVFEIPKSYHVQDDGRNIHVHDEDNEIMQFAIQQSLLESSGNKEVGAHSNGAVAYSQDFNIQYQRALQESYLTSTGNSQCSSPSEPSSFEKDLQLAMELSVREQEERERQRREEEDAELQQVLQLSLVEK", "length": 594, "header": "tr|A0A8V0ZT30-1|A0A8V0ZT30_CHICK Isoform 1 of Ankyrin repeat domain 13A OS=Gallus gallus OX=9031 GN=ANKRD13A PE=1 SV=1 CANONICAL=A0A8V0ZT30-1" }, "locus": { "chromosome": "15", "start_pos": 6906855, "end_pos": 6896307, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053074.1", "url": "https://www.ensembl.org/id/ENSGALT00010053074.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031967.1", "url": "https://www.ensembl.org/id/ENSGALP00010031967.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:416902", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416902", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287AJ61-1", "protein_name": "Ankyrin repeat domain 13A", "gene_name": "ANKRD13A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSSACDASRHFPLHLLVWNNDYRQLEKELRGQNVEALDPRGRSLLHLAVSLGHLESARVLLRHKADVTKENREGWTVLHEAVSTGDPEMVYTVLQHRDYHNTTMALEGVPELLRKILEAPDFYVQMKWEFTSWVPLVSRICPNDVCRIWKSGAKLRVDITLLGFENMSWIRGRRSFIFKGEDNWAELMEVNHDDKVVTTEHFDLSQEMERLTLDLMKPKGREVERRLTSPVINTSLDTKNIAFERTKSGFWGWRTDKAEVVNGYEAKVYTVNNVSVITKIRTEHLTEEEKKRYKADRNPLESLLGTVEHQFGAQGDLTTECATANNPTAITPDEYFNEEFDLKDRDIGRPKELTIRTQKFKATLWMCEEFPLSLVEQVIPIIDLMARTSAHFARLRDFIKLEFPPGFPVKIEIPLFHVLNARITFGNVNGCSTAEENISQNAEGTQLDSASPLTNFEVDQSVFEIPESYHVQDNGRNMHLQDEDYEIMQFAIQQSLLESTRSQDQLLMEALARHIPTTPSTREPSRRASSPAQKALAPAVRPAALTATCSWPWSSLPKSWRSVSFGCRRRRRSCSRSYSCHSPRSRPSRLLPTHTKQTLCLRHGGTVPHPEAAEGSCPLLYAEVPGHPGPPTTLPREGAGVLRPHLQA", "length": 648 }, "evidence": [ { "id": "A0A8V0ZT30", "url": "https://omabrowser.org/oma/group/A0A8V0ZT30/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A2BG46-1", "protein_name": "Ankyrin repeat domain-containing protein 13A", "gene_name": "ankrd13a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLSASAASVEDFSLRFPLHVLVWENDYRKLETEIQTSNIEEVDPRGRTPLHLAVSLGHLESVRVLLRHGADVAKENGKNWTVLQEAVSTGDPEMVQLVLQRRDYLKASTALGGVPELLCKIRESPDFYMEMKWEFTSWIPLVSRVCPSDVCRIWKSGACLRVDTTLLGFENMTWIRGRRSYIFRGEDNCTELMEVNHEDEVVDTERFDLSREMEDVTLDSMQPAEQEVAKRLTTSIVNTYLDTKDIAFERNAIKTFTRSILRAKSGIWGWRSDRTEVVNGYEAKVFSVNNVNVVIRTRTEHLTDEEKARIKSERNVLESLLGTVEQQIGAQGDMTMEFATATNPTAITPEEYFNPNFDLQGRDIGRPIELTIRTQKFKGTLWMSEEHPLSLVEQVTPIIDLMARTSTHFARLKDFINLRFPPGFPVKIEIPLFHVLNARITFGSVNKCSTDEPLDTKTPASTPTPTEETCDNQAAAPAGPAPLFQVSPSVFLAPAHYHHRGGYRHANPRQYNPVNHDEELLQYAIHQSLLDSSVLNSQDTWSDSDGQATQSMTNRLSDGSGSEGVLVDLSDTTPSSSGSASSPDTDLRLAMELSARAQEEEEKRRKEEEEELERILQLSLTEK", "length": 623 }, "evidence": [ { "id": "A0A8V0ZT30", "url": "https://omabrowser.org/oma/group/A0A8V0ZT30/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1N545-1", "protein_name": "Ankyrin repeat domain 13A", "gene_name": "ANKRD13A", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSSPRDASGDFPLHLLVWNNDYRQLEKELRDQNVEALDPRGRTLLHLAVSLGHLESARVLLRHKADVTKENREGWTVLHEAVSTGDPEMVYTVLQHRDFHNTSMALEGVPELLQKILEVAPDFYVQMKWEFTSWVPLVSRICPNDVCRIWKSGAKLRVDITLLGFENMSWIRGRRSFIFKGEDNWAELMEVNHDDKVVTTEHFDLSQEMERLTLDLMKPKSREVERRLTSPVINTSLDTKNIAFERTKSGFWGWRTDKAEVVNGYEAKVYTVNNVSVITKIRTEHLTEEEKKRYKADRNPLESLLGTVEHQFGAQGDLTTECATAHNPTAITPDEYFNEEFDLKDRDIGRPKELTIRTQKFKATLWMCEEFPLSLVEQVVPIIDLMARTSAHFARLRDFIKLEFPPGFPVKIEIPLFHVLNARITFGNVNGCSTAEETVSQHVEGTQPDSASPLTNFEVDQSVFEIPESYHVQDNGRNVHLQDEDYEIMQFAIQQSLLESSRSQELSGPASNGGINQAHAYDAQYERAIQESLLSSSEGLGSGTSSETSRFDSDLQLAMELSAKELEERELRLREEEAELQQVLQLSLTEK", "length": 591 }, "evidence": [ { "id": "A0A8V0ZT30", "url": "https://omabrowser.org/oma/group/A0A8V0ZT30/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q80UP5-1", "protein_name": "Ankyrin repeat domain-containing protein 13A", "gene_name": "Ankrd13a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSARDTSSRFPLHLLVWNNDYEQLEKELRDQNAEALDPRGRTLLHLAVSLGHLESARVLLRHKADVTKENGQGWTVLHEAVSTGDPEMVYTVLQHRDYHNTSMALEGVPELLHKILEAPDFYVQMKWEFTSWVPLVSRICPNDVCRIWKSGAKLRVDITLLGFENMSWIRGRRSFIFKGGDNWAELMEVNHDDRVVTTEHFDLSQEMERLTLDLMKPKSREVERRLTSPVINTSLDTKNVAFERTKSGFWGWRTDKAEVVNGYEAKVYSVNNVSVITRIRTEHLTEEEKKRYKEDRNPLESLLGTVEHQFGAQGDLATECATVNNPTAITPDEYFDEDFDLKDRDIGRPKELTIRTQKFKATLWMCEEFPLSLVEQVIPIIDLMARTSAHFARLRDFIKLDFPPGFPVKIEIPLFHVLNARITFGNVNGCSTADESQGVEGTPAEAVSEATNFEVDQSVFEIPESYHIQDNGRNVHLQDEDYEIMQFAIQQSLLESSRSQDLSGPASNGGVSHTHSYEAQYERAIQESLLTNMEGRCPGGLSESSRFDSDLQLAMELSAKELAERELRLQEEEAELQQVLQLSLTEK", "length": 588 }, "evidence": [ { "id": "A0A8V0ZT30", "url": "https://omabrowser.org/oma/group/A0A8V0ZT30/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8IZ07-1", "protein_name": "Ankyrin repeat domain-containing protein 13A", "gene_name": "ANKRD13A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSSACDAGDHYPLHLLVWKNDYRQLEKELQGQNVEAVDPRGRTLLHLAVSLGHLESARVLLRHKADVTKENRQGWTVLHEAVSTGDPEMVYTVLQHRDYHNTSMALEGVPELLQKILEAPDFYVQMKWEFTSWVPLVSRICPNDVCRIWKSGAKLRVDITLLGFENMSWIRGRRSFIFKGEDNWAELMEVNHDDKVVTTERFDLSQEMERLTLDLMKPKSREVERRLTSPVINTSLDTKNIAFERTKSGFWGWRTDKAEVVNGYEAKVYTVNNVNVITKIRTEHLTEEEKKRYKADRNPLESLLGTVEHQFGAQGDLTTECATANNPTAITPDEYFNEEFDLKDRDIGRPKELTIRTQKFKAMLWMCEEFPLSLVEQVIPIIDLMARTSAHFARLRDFIKLEFPPGFPVKIEIPLFHVLNARITFGNVNGCSTAEESVSQNVEGTQADSASHITNFEVDQSVFEIPESYYVQDNGRNVHLQDEDYEIMQFAIQQSLLESSRSQELSGPASNGGISQTNTYDAQYERAIQESLLTSTEGLCPSALSETSRFDNDLQLAMELSAKELEEWELRLQEEEAELQQVLQLSLTDK", "length": 590 }, "evidence": [ { "id": "A0A8V0ZT30", "url": "https://omabrowser.org/oma/group/A0A8V0ZT30/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9M840-1", "protein_name": "Ankyrin repeat family protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEDYSKYTHSPAHLAVVLRDHAALRRIVSDLPRLAKAGEVTTEAESMESESRADSVSAVIDRRDVPGRETPLHLAVRLRDPVSAEILMSAGADWSLQNENGWSALQEAVCTREEAIAMIIARHYQPLAWAKWCRRLPRIIASASRIRDFYMEITFHFESSVIPFIGRIAPSDTYRIWKRGSNLRADMTLAGFDGFKIQRSDQTFLFLGDGYSSEDGKMSLSPGSLIVLSHKEKEMTNALEGAGAQPTDAEVAHEVALMSQTNMYRPGIDVTQAELVSHLNWRRQERTEMVGNWKAKVYDMLHVMVSVKSRRVPGAMTDEELFAVDEERTAVTNGAETDGFEDVLTPEERLQLNSALQTGNSDAIEDEECEVTDQQENGALKDKKGWFGWNKKGSNTEDTKLKKGSKSAPEDGNQKGKSQKSSMVSDHANEDHGDAKKGKEKKKKKKGVAGDEVKRESEYKKGLRPVLWLTPDFPLTTDELLPLLDILANKVKAVRRLRELLTTKLPLGTFPVKLAIPIIPTVRVVVTFTKFEELQAAEEEFSTPPSSPVFHDAKSSSSENSSPSWISWMRSGKSSDNDSNRYKDEADPFLIPSDYKWIDSAEKKRRMKAKKAKSRRKKQAATKAAGASDSGTRSNHVAEE", "length": 640 }, "evidence": [ { "id": "A0A8V0ZT30", "url": "https://omabrowser.org/oma/group/A0A8V0ZT30/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "ubiquitin-modified protein reader activity", "id": "GO:0140036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140036", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZT30", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT30" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZT30", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT30" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZT30", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT30" } ], "pmid": "" }, { "name": "late endosome", "id": "GO:0005770", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005770", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZT30", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT30" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "negative regulation of receptor internalization", "id": "GO:0002091", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002091", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZT30", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT30" } ], "pmid": "" }, { "name": "regulation of receptor-mediated endocytosis", "id": "GO:0048259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048259", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZT30", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT30" } ], "pmid": "" }, { "name": "negative regulation of protein localization to endosome", "id": "GO:1905667", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905667", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZT30", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT30" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 122, "end_pos": 124, "annotation": "n_glycosylation_sequon" }, { "start_pos": 171, "end_pos": 173, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZT30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT30" }, { "id": "PF11904", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11904" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ankyrin repeat", "eco_id": "ECO_0000259", "start_pos": 161, "end_pos": 474, "start_aa": "Arg", "end_aa": "His", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 122, "end_pos": 124 }, { "start_pos": 171, "end_pos": 173 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZT33-1", "uniprot_ac": "A0A8V0ZT33", "uniprot_id": "A0A8V0ZT33_CHICK", "mass": { "chemical_mass": 18708.0, "monoisotopic_mass": 18708.0 }, "refseq": { "ac": "XP_004942445", "name": "MARVEL domain-containing protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004942445" }, "gene_names": [ { "name": "MARVELD1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZT33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT33" } ] }, { "name": "MARVELD1", "type": "synonym", "evidence": [ { "id": "XP_004942445", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004942445" } ] } ], "protein_names": [ { "name": "MARVEL domain containing 1", "type": "synonym", "evidence": [ { "id": "A0A8V0ZT33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT33/entry#names_and_taxonomy" } ] }, { "name": "MARVEL domain-containing protein 1", "type": "synonym", "evidence": [ { "id": "XP_004942445", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004942445" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052537.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jan 4, 2016 this sequence version replaced XP_004942445.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004942445", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004942445" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZT33", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT33" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MARVELD1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT33", "locus": { "chromosome": "6", "start_pos": 23096912, "end_pos": 23097442, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022840", "url": "https://www.ensembl.org/id/ENSGALG00010022840" } ] } } ], "crossref": [ { "id": "A0A8V0ZT33", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZT33", "database": "AlphaFoldDB", "categories": [] }, { "id": "100858221", "url": "https://www.ncbi.nlm.nih.gov/gene/100858221", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR008253", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008253", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:100858221", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100858221", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "AAHKYEG", "url": "https://omabrowser.org/oma/group/AAHKYEG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZT33", "url": "https://www.orthodb.org/?gene=A0A8V0ZT33", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PF01284", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01284", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004942445", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004942445", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZT33", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT33", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZT33-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT33-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MARTAPPAVPPPPPGPPPRGSLGLHRAFLRSPLGLLRLGQLAVGAAFWLTVAAHWYEGAAHFALFAAVLVWLLTLGLFGLSALGRWELVPWLGSRWLLANLAHDLVLGVGLCTAAAGIMGHKAGQKSYCNLPGYSQRCLYGAYLGAAVCGAVAACLYLFSGLYCLARRCRDQRDIV", "length": 176, "header": "tr|A0A8V0ZT33-1|A0A8V0ZT33_CHICK Isoform 1 of MARVEL domain containing 1 OS=Gallus gallus OX=9031 GN=MARVELD1 PE=4 SV=1 CANONICAL=A0A8V0ZT33-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZT33-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT33/entry#A0A8V0ZT33-1", "sequence": { "sequence": "MARTAPPAVPPPPPGPPPRGSLGLHRAFLRSPLGLLRLGQLAVGAAFWLTVAAHWYEGAAHFALFAAVLVWLLTLGLFGLSALGRWELVPWLGSRWLLANLAHDLVLGVGLCTAAAGIMGHKAGQKSYCNLPGYSQRCLYGAYLGAAVCGAVAACLYLFSGLYCLARRCRDQRDIV", "length": 176, "header": "tr|A0A8V0ZT33-1|A0A8V0ZT33_CHICK Isoform 1 of MARVEL domain containing 1 OS=Gallus gallus OX=9031 GN=MARVELD1 PE=4 SV=1 CANONICAL=A0A8V0ZT33-1" }, "locus": { "chromosome": "6", "start_pos": 23097442, "end_pos": 23096915, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055567.1", "url": "https://www.ensembl.org/id/ENSGALT00010055567.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033672.1", "url": "https://www.ensembl.org/id/ENSGALP00010033672.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:100858221", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100858221", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1S8X5-1", "protein_name": "MARVEL domain containing 1", "gene_name": "MARVELD1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLPPPPRQPPPQARTARGAVSLQRAFLRGPLGVLRLLQLLAGAAFWITIATSRYQGPVHFALFVSVLFWLLTLGLYFLTLLGKHELVPVLGSRWLVVNVAHDLLAAALYGAATGIMISQTQSHSYCNLKDYQMSCAYHAFLAAAVCGGLCLGLYLLSALYGCCRHYQGEQEVA", "length": 173 }, "evidence": [ { "id": "A0A8V0ZT33", "url": "https://omabrowser.org/oma/group/A0A8V0ZT33/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q5BLB7-1", "protein_name": "MARVEL domain-containing protein 1", "gene_name": "marveld1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MPTQPQEKRSFLQFLKSFVGIVRVLQILLGAGLWVTIAANKYEGSIHFVLFVAVLFWLLTLAIFILTLLDKQDLVPIVGGERWLLSNLIHDVVATLLYLSTIGIMIYKTQKNSYCNLDVYKHHCLYKVYLTASVFACLTAAVYLLSGIYCSCRKCRGERTVV", "length": 162 }, "evidence": [ { "id": "A0A8V0ZT33", "url": "https://omabrowser.org/oma/group/A0A8V0ZT33/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q7TQJ1-1", "protein_name": "MARVEL domain-containing protein 1", "gene_name": "Marveld1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLPPPPRQPPPQARTARGSLRLQRAFLRGPLGVLRLLQLLAGAAFWITIATSKYQGPVHFALFVSVLFWLLTLGLYFITLLGKQELVPVLGSRWLVVNVAHDLLAAALYGAATGIMIDQTQRHSYCNLKNYRLPCAYHAFLAASVCGGLCLGLYLLSALYGCCRRYQGKEEVV", "length": 173 }, "evidence": [ { "id": "A0A8V0ZT33", "url": "https://omabrowser.org/oma/group/A0A8V0ZT33/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9BSK0-1", "protein_name": "MARVEL domain-containing protein 1", "gene_name": "MARVELD1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLPPPPRQPPPQARAARGAVRLQRPFLRSPLGVLRLLQLLAGAAFWITIATSKYQGPVHFALFVSVLFWLLTLGLYFLTLLGKHELVPVLGSRWLMVNVAHDVLAAALYGAATGIMSDQMQRHSYCNLKDYPLPCAYHAFLAAAVCGGVCHGLYLLSALYGCGRRCQGKQEVA", "length": 173 }, "evidence": [ { "id": "A0A8V0ZT33", "url": "https://omabrowser.org/oma/group/A0A8V0ZT33/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZT33", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT33" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZT33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT33" }, { "id": "PS51225", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51225" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "MARVEL", "eco_id": "ECO_0000259", "start_pos": 28, "end_pos": 169, "start_aa": "Phe", "end_aa": "Cys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZT35-1", "uniprot_ac": "A0A8V0ZT35", "uniprot_id": "A0A8V0ZT35_CHICK", "mass": { "chemical_mass": 99894.0, "monoisotopic_mass": 99894.0 }, "refseq": { "ac": "XP_015134705", "name": "breast cancer anti-estrogen resistance protein 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015134705" }, "gene_names": [ { "name": "BCAR1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZT35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT35" } ] }, { "name": "BCAR1", "type": "synonym", "evidence": [ { "id": "XP_015134705", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015134705" } ] } ], "protein_names": [ { "name": "Breast cancer anti-estrogen resistance protein 1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZT35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT35/entry#names_and_taxonomy" } ] }, { "name": "CRK-associated substrate", "type": "synonym", "evidence": [ { "id": "A0A8V0ZT35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT35/entry#names_and_taxonomy" } ] }, { "name": "breast cancer anti-estrogen resistance protein 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015134705", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015134705" } ] }, { "name": "p130cas", "type": "synonym", "evidence": [ { "id": "A0A8V0ZT35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT35/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052542.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015134705.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015134705", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015134705" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZT35", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT35" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "BCAR1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT35", "locus": { "chromosome": "11", "start_pos": 1993960, "end_pos": 1999630, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010023431", "url": "https://www.ensembl.org/id/ENSGALG00010023431" } ] } } ], "crossref": [ { "id": "A0A8V0ZT35", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZT35", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd11552", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11552", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd11569", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11569", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12001", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12001", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "415691", "url": "https://www.ncbi.nlm.nih.gov/gene/415691", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014928", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014928", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021901", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021901", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035745", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035745", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036028", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036028", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037362", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037362", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038319", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038319", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046976", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046976", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:415691", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415691", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MTPHRPA", "url": "https://omabrowser.org/oma/group/MTPHRPA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZT35", "url": "https://www.orthodb.org/?gene=A0A8V0ZT35", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A0N9", "url": "https://www.orthodb.org/?gene=A0A8V1A0N9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10654", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10654", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10654:SF15", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10654:SF15", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00018", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00018", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08824", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08824", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12026", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12026", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-186763", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-186763", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-372708", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-372708", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-4420097", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4420097", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015134705", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015134705", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZT35", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT35", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZT35-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT35-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A0N9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0N9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A0N9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0N9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTPDPPRRGALLQNVLAKALYDNVAESPDELSFRKGDIMTVLERNTQGLDGWWLCSLHGRQGIVPGNRLKILVGMYDKKQQQQQQQQQQAAGPGQGQAPPAPQPTLPYHHQGGYAPLSPASQYTPMHPSYVPQGDNVYLMPVPGKGQQGHYSGSAPSGQFPPAPAKQPPAYPKQTPPHAFPSAGQEIYQVPPSLSQAADAYPVGSASPPQDIYQVPPSVAQAQDIYQVPPSLDARSWEGPKPSGKVLLPTRVGQVYVYDSPKGEQDEYDFPRHLLSSGSQEIYDVPPVRGALPSQQVYDTPPMAVKGPNGQDPGQEIYDVPPSVEKNLHQTVYDVPPSVSKDVPDGPVREETYDVPPAFAKQKAFEPSRHPPVLTQQEPYLPEDVYDVPPAAGKAAPEPSLSHEIYDVPPSLKKLGGSAFPSQEVYDVPRDLHAPGKGSVDMEGEYIYDVPPQVDREAKAPDNKRLSASSTGSTRSNISTSSLDTVPVKEPPKGAGREFSLDLDAAMEMLAKLQLGVSSAVSCLMSFISTNWRSPEHMEANAAGIHGAAEGVQTALRELLEFARGAVGNAAQASDRSLYAKLSKQLQKMEEVYQALGRHSQALDACHWAPSALVAGKPGTDDLELFVMYSRGVPDDTKQLASFLHGNASLLFKRTKPAPEGNGHGPTHPSDKASSIQSRPLPSPPKLLAQESPEGPYENHESGWMEDYDYVHLQGKEEFEKTQKELLEKGNIIRQSKDQLEHQQLKQFERLEQEVTRPIDNDLSNWSPPQHYGPVRGGGALCAADRQLLLFYLEQCEANLTTLTNAIDAFFTAISTNQPPKIFVAHSKFIILSAHKLVFIGDTLSRQAKAQDVRHKVTHYSNLLCELLKEIVVSTKAAALHYPSPAASKDMVERVKDLANSTQQFRMVLGQLAAM", "length": 915, "header": "tr|A0A8V0ZT35-1|A0A8V0ZT35_CHICK Isoform 1 of Breast cancer anti-estrogen resistance protein 1 OS=Gallus gallus OX=9031 GN=BCAR1 PE=1 SV=1 CANONICAL=A0A8V0ZT35-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZT35-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT35/entry#A0A8V0ZT35-1", "sequence": { "sequence": "MTPDPPRRGALLQNVLAKALYDNVAESPDELSFRKGDIMTVLERNTQGLDGWWLCSLHGRQGIVPGNRLKILVGMYDKKQQQQQQQQQQAAGPGQGQAPPAPQPTLPYHHQGGYAPLSPASQYTPMHPSYVPQGDNVYLMPVPGKGQQGHYSGSAPSGQFPPAPAKQPPAYPKQTPPHAFPSAGQEIYQVPPSLSQAADAYPVGSASPPQDIYQVPPSVAQAQDIYQVPPSLDARSWEGPKPSGKVLLPTRVGQVYVYDSPKGEQDEYDFPRHLLSSGSQEIYDVPPVRGALPSQQVYDTPPMAVKGPNGQDPGQEIYDVPPSVEKNLHQTVYDVPPSVSKDVPDGPVREETYDVPPAFAKQKAFEPSRHPPVLTQQEPYLPEDVYDVPPAAGKAAPEPSLSHEIYDVPPSLKKLGGSAFPSQEVYDVPRDLHAPGKGSVDMEGEYIYDVPPQVDREAKAPDNKRLSASSTGSTRSNISTSSLDTVPVKEPPKGAGREFSLDLDAAMEMLAKLQLGVSSAVSCLMSFISTNWRSPEHMEANAAGIHGAAEGVQTALRELLEFARGAVGNAAQASDRSLYAKLSKQLQKMEEVYQALGRHSQALDACHWAPSALVAGKPGTDDLELFVMYSRGVPDDTKQLASFLHGNASLLFKRTKPAPEGNGHGPTHPSDKASSIQSRPLPSPPKLLAQESPEGPYENHESGWMEDYDYVHLQGKEEFEKTQKELLEKGNIIRQSKDQLEHQQLKQFERLEQEVTRPIDNDLSNWSPPQHYGPVRGGGALCAADRQLLLFYLEQCEANLTTLTNAIDAFFTAISTNQPPKIFVAHSKFIILSAHKLVFIGDTLSRQAKAQDVRHKVTHYSNLLCELLKEIVVSTKAAALHYPSPAASKDMVERVKDLANSTQQFRMVLGQLAAM", "length": 915, "header": "tr|A0A8V0ZT35-1|A0A8V0ZT35_CHICK Isoform 1 of Breast cancer anti-estrogen resistance protein 1 OS=Gallus gallus OX=9031 GN=BCAR1 PE=1 SV=1 CANONICAL=A0A8V0ZT35-1" }, "locus": { "chromosome": "11", "start_pos": 1998729, "end_pos": 1994521, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010057094.1", "url": "https://www.ensembl.org/id/ENSGALT00010057094.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034728.1", "url": "https://www.ensembl.org/id/ENSGALP00010034728.1" } ] } }, { "isoform_ac": "A0A8V1A0N9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT35/entry#A0A8V1A0N9-1", "sequence": { "sequence": "MNYLNVLAKALYDNVAESPDELSFRKGDIMTVLERNTQGLDGWWLCSLHGRQGIVPGNRLKILVGMYDKKQQQQQQQQQQAAGPGQGQAPPAPQPTLPYHHQGGYAPLSPASQYTPMHPSYVPQGDNVYLMPVPGKGQQGHYSGSAPSGQFPPAPAKQPPAYPKQTPPHAFPSAGQEIYQVPPSLSQAADAYPVGSASPPQDIYQVPPSVAQAQDIYQVPPSLDARSWEGPKPSGKVLLPTRVGQVYVYDSPKGEQDEYDFPRHLLSSGSQEIYDVPPVRGALPSQQVYDTPPMAVKGPNGQDPGQEIYDVPPSVEKNLHQTVYDVPPSVSKDVPDGPVREETYDVPPAFAKQKAFEPSRHPPVLTQQEPYLPEDVYDVPPAAGKAAPEPSLSHEIYDVPPSLKKLGGSAFPSQEVYDVPRDLHAPGKGSVDMEGEYIYDVPPQVDREAKAPDNKRLSASSTGSTRSNISTSSLDTVPVKEPPKGAGREFSLDLDAAMEMLAKLQLGVSSAVSCLMSFISTNWRSPEHMEANAAGIHGAAEGVQTALRELLEFARGAVGNAAQASDRSLYAKLSKQLQKMEEVYQALGRHSQALDACHWAPSALVAGKPGTDDLELFVMYSRGVPDDTKQLASFLHGNASLLFKRTKPAPEGNGHGPTHPSDKASSIQSRPLPSPPKLLAQESPEGPYENHESGWMEDYDYVHLQGKEEFEKTQKELLEKGNIIRQSKDQLEHQQLKQFERLEQEVTRPIDNDLSNWSPPQHYGPVRGGGALCAADRQLLLFYLEQCEANLTTLTNAIDAFFTAISTNQPPKIFVAHSKFIILSAHKLVFIGDTLSRQAKAQDVRHKVTHYSNLLCELLKEIVVSTKAAALHYPSPAASKDMVERVKDLANSTQQFRMVLGQLAAM", "length": 906, "header": "tr|A0A8V1A0N9-1|A0A8V0ZT35_CHICK Computationally mapped isoform of Breast cancer anti-estrogen resistance protein 1 OS=Gallus gallus OX=9031 GN=BCAR1 PE=1 SV=1 CANONICAL=A0A8V0ZT35-1" }, "locus": { "chromosome": "11", "start_pos": 1999530, "end_pos": 1994521, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010057100.1", "url": "https://www.ensembl.org/id/ENSGALT00010057100.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034732.1", "url": "https://www.ensembl.org/id/ENSGALP00010034732.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:415691", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415691", "resource": "KEGG Pathway" }, { "id": "R-GGA-186763", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-186763", "resource": "Reactome", "description": "Downstream signal transduction" }, { "id": "R-GGA-372708", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-372708", "resource": "Reactome", "description": "p130Cas linkage to MAPK signaling for integrins" }, { "id": "R-GGA-4420097", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4420097", "resource": "Reactome", "description": "VEGFA-VEGFR2 Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287BKY6-1", "protein_name": "Breast cancer anti-estrogen resistance protein 1", "gene_name": "BCAR1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSVPNVLAKALYDNVAESPDELSFRKGDIMTVLERDTQGLDGWWLCSLHGRQGIVPGNRLKILVGMHDKKPVGPGPGPPASSAPPQPSLHAPAAQYTPMLPAAYQPQPDSVYLVPTPSKTQQGLYQAPGPSSQFQSPPAKQTSTFSKQMPHHPFPSPAPDLYQVPPGPGNPAQDIYQVPPSAGMGHDIYQVPPSMDARSWEGTKAPAKVAVPTRVGQGYVFETSQPEQDEYDIPRHLLAPGPQDIYDVPPVRGLLPSQYGQEVYDTPPMAVKGPNGRDPSMDVYDVPPSVEKALPPSNHHAVYDVPPSVVKDVPDGPLLREETYDVPPAFTKAKPFDPMRHPLVLAAPPPDSPPAEDVYDVPPPAPDLYDVPPGLRRLGPGTLYDVPRERVLPPEAADGGGADDGVYAVPPPAEREAPGDAKRLSASSTGSTRSSLSASSLEAAVPGREPLELEVAVEALARLQQGVSATVAHLLDLAGSAGGCGGWRSTPEPQEPPAQDLRAAVAAVHGAVHELLEFARSAVGNAAHTSDRTLHAKLSRQLQKMEDVYQTLVAHGQALDSGWGGLGATPEDLDRLVACSRAVPEDAKQLASFLHGNASLLFRRTKASVPGPEGGGSLHPNPTDKASSIQSRPLPSPPKFTSQDSPEGQYENSEGGWMEDYDYVHLQGKEEFEKTQKELLEKGNIMRQGKGQLELQQLKQFERLEQEVSRPIDHDLANWTPAQPLAPGRTGGLGPSDRQLLLFYLEQCEANLTTLTNAVDAFFTAVATNQPPKIFVAHSKFVILSAHKLVFIGDTLSRQAKAADVRSQVTHYSNLLCDLLRGIVATTKAAALQYPSPAAAQDMVDRVKELGHSTQQFRRVLGQLAAA", "length": 867 }, "evidence": [ { "id": "A0A8V0ZT35", "url": "https://omabrowser.org/oma/group/A0A8V0ZT35/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8M9PM80-1", "protein_name": "Breast cancer anti-estrogen resistance protein 1", "gene_name": "bcar1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSVPVFCKMFDCLQGTSAEIGSRPLNPSSAGSAALLDHHLLHSDPLNVLAKALYDNVAESPDELSFRKGDIMTVLERDTQGLEGWWLCSLHGRQGIVPGNRLKILVGMYDKQQQQQLQQLANQPSPTQSLINLPQSAYNKIPPAAQYTAMHPAFTPSGSANSTNPDGVYMLPPSHGSSLYQVPSGPPTPQPQPKAPALAKKQTHVQYPPTTQDVYQVPPSINAPGQDIYQVPPAAGGQCPGQDVYQVPPSVNQTQDVYQIPPSLDRSWDSPKPMGKVVVPTRVGQVYVYDTGKNEQDEYDVPRHLPPSQDIYDVPPTRTQYIQQVYDTPPMAMKGPPSGQEIYDTPPSVDKSQLHYQQTVYDIPPSVSKDVPDGPIREETYDVPPHFAKMKSLENQNQAYLSQIPGGPEPPIPEDVYDVPPPQLIGKRQPEGQEIYDIPASLRKGGPQDHHPTDVYDFPRERPAGEDSGDYVYDVPPQVVRDAAATEELTVSFKRLSASSTGSTRSNLSTSSLDMVPVRESSGPGRLLLLDLDQAMERLSRHQQAVESSVSLLMSFISGNWRSSTQMESNLPAIRQAVDRIRVAVRDLLEFARGAVANATQATDRTLQTKLGKQVQKMEEAFQGLVRYSQALDTLGWSPAALMTSQPGTGGDDLDRLIMCARGVPDDTKQLASFLHGNASLLFKRTNKQQQLPLPPVPHTGDSLTNNNNISAYQSGTPERANIQSRPLPSPPKFSAEEEAPDRPYETTEEGWMEDYDYVHLQGKEEFEKNQRQLLEKGSIKQNKTQLEQQQLKQFERLEQEVSRPINNDISGWTPPSHYPQTQRSKLCMGDRQLLLFYMEQCEANITTLTNAIDAFYSSINNNQPPKIFVAHSKFVILSAHKLVFIGDTLSRQAKSPEVRTRVAQHSNTLCDKLKDIVVSTKTAALQYPSPGSTRDMTERVRELAGCTQQFRMALNQLLAM", "length": 961 }, "evidence": [ { "id": "A0A8V0ZT35", "url": "https://omabrowser.org/oma/group/A0A8V0ZT35/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "P56945-1", "protein_name": "Breast cancer anti-estrogen resistance protein 1", "gene_name": "BCAR1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNHLNVLAKALYDNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIVPGNRLKILVGMYDKKPAGPGPGPPATPAQPQPGLHAPAPPASQYTPMLPNTYQPQPDSVYLVPTPSKAQQGLYQVPGPSPQFQSPPAKQTSTFSKQTPHHPFPSPATDLYQVPPGPGGPAQDIYQVPPSAGMGHDIYQVPPSMDTRSWEGTKPPAKVVVPTRVGQGYVYEAAQPEQDEYDIPRHLLAPGPQDIYDVPPVRGLLPSQYGQEVYDTPPMAVKGPNGRDPLLEVYDVPPSVEKGLPPSNHHAVYDVPPSVSKDVPDGPLLREETYDVPPAFAKAKPFDPARTPLVLAAPPPDSPPAEDVYDVPPPAPDLYDVPPGLRRPGPGTLYDVPRERVLPPEVADGGVVDSGVYAVPPPAEREAPAEGKRLSASSTGSTRSSQSASSLEVAGPGREPLELEVAVEALARLQQGVSATVAHLLDLAGSAGATGSWRSPSEPQEPLVQDLQAAVAAVQSAVHELLEFARSAVGNAAHTSDRALHAKLSRQLQKMEDVHQTLVAHGQALDAGRGGSGATLEDLDRLVACSRAVPEDAKQLASFLHGNASLLFRRTKATAPGPEGGGTLHPNPTDKTSSIQSRPLPSPPKFTSQDSPDGQYENSEGGWMEDYDYVHLQGKEEFEKTQKELLEKGSITRQGKSQLELQQLKQFERLEQEVSRPIDHDLANWTPAQPLAPGRTGGLGPSDRQLLLFYLEQCEANLTTLTNAVDAFFTAVATNQPPKIFVAHSKFVILSAHKLVFIGDTLSRQAKAADVRSQVTHYSNLLCDLLRGIVATTKAAALQYPSPSAAQDMVERVKELGHSTQQFRRVLGQLAAA", "length": 870 }, "evidence": [ { "id": "A0A8V0ZT35", "url": "https://omabrowser.org/oma/group/A0A8V0ZT35/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q61140-1", "protein_name": "Breast cancer anti-estrogen resistance protein 1", "gene_name": "Bcar1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTVPNVLAKALYDNVAESPDELSFRKGDIMTVLERDTQGLDGWWLCSLHGRQGIVPGNRLKILVGMYDKKPVGPGPGPPATPPQPQPSLPQGVHAPVPPASQYSPMLPTAYQPQSDNVYLVPTPSKTQQGLYQAPGPNPQFQSPPAKQTSTFSKQTPHHSFPSPATDLYQVPPGPGSPAQDIYQVPPSAGIGHDIYQVPPSLDTRGWEGTKPPAKVVVPTRVGQGYVYEAAQTEQDEYDTPRHLLAPGPQDIYDVPPVRGLLPNQYGQEVYDTPPMAVKGPNGRDPLLDVYDVPPSVEKGLLSSSHHSVYDVPPSVSKDVPDGPLLREETYDVPPAFAKPKPFDPTRHPLILAAPPPDSPAAEDVYDVPPPAPDLYDVPPGLRRPGPGTLYDVPRERVLPPEVADGSVVDDGVYAVPPPAEREAPTDGKRLSASSTGSTRSSQSASSLEVVVPGREPLELEVAVESLARLQQGVSTTVAHLLDLVGSASGPGGWRGTSEPQEPPAQDLKAAVAAVHGAVHELLEFARGAVSNATHTSDRTLHAKLSRQLQKMEDVYQTLVVHGQVLDSGRGSPGFTPEDLDRLVACSRAVPEDAKQLASFLHGNASLLFRRTKAPGPGPEGSSSLHPNPTDKASSIQSRPLPSPPKFTSQDSPDGQYENSEGGWMEDYDYVHLQGKEEFEKTQKELLERGNIMRQGKGQLELQQLKQFERLEQEVSRPIDHDLANWTPAQPLVPGRTGGLGPSDRQLLLFYLEQCEANLTTLTDAVDAFFTAVATNQPPKIFVAHSKFVILSAHKLVFIGDTLSRQAKAADVRSQVTHYSNLLCDLLRGIVATTKAAALQYPSPSAAQDMVDRVKELGHSTQQFRRVLGQLAAA", "length": 874 }, "evidence": [ { "id": "A0A8V0ZT35", "url": "https://omabrowser.org/oma/group/A0A8V0ZT35/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q63767-1", "protein_name": "Breast cancer anti-estrogen resistance protein 1", "gene_name": "Bcar1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKYLVSVGAGPARRAGGLEDVSWGPRVSRRPQSYRAARHVNESLPRSAFRVPAAHGASVTPSAALGSGLPETQPEAVCRGTEKPRFAEGCKPAASRDKNVLAKALYDNVAESPDELSFRKGDIMTVLERDTQGLDGWWLCSLHGRQGIVPGNRLKILVGMYDKKPAAPGPGPPATPPQPQPSLPQGVHTPVPPASQYSPMLPTAYQPQPDNVYLVPTPSKTQQGLYQAPGPNPQFQSPPAKQTSTFSKQTPHHSFPSPATDLYQVPPGPGSPAQDIYQVPPSAGTGHDIYQVPPSLDTRSWEGTKPPAKVVVPTRVGQGYVYEASQAEQDEYDTPRHLLAPGSQDIYDVPPVRGLLPNQYGQEVYDTPPMAVKGPNGRDPLLDVYDVPPSVEKGLPPSNHHSVYDVPPSVSKDVPDGPLLREETYDVPPAFAKPKPFDPTRHPLILAAPPPDSPPAEDVYDVPPPAPDLYDVPPGLRRPGPGTLYDVPRERVLPPEVADGSVIDDGVYAVPPPAEREAPTDGKRLSASSTGSTRSSQSASSLEVVVPGREPLELEVAVETLARLQQGVSTTVAHLLDLVGSASGPGGWRSTSEPQEPPVQDLKAAVAAVHGAVHELLEFARSAVSSATHTSDRTLHAKLSRQLQKMEDVYQTLVVHGQVLDSGRGGPGFTLDDLDRLVACSRAVPEDAKQLASFLHGNASLLFRRTKAPGPGPEGSSSLHLNPTDKASSIQSRPLPSPPKFTSQDSPDGQYENSEGGWMEDYDYVHLQGKEEFEKTQKELLEKGNIVRQGKGQLELQQLKQFERLEQEVSRPIDHDLANWTPAQPLVPGRTGGLGPSDRQLLLFYLEQCEANLTTLTDAVDAFFTAVATNQPPKIFVAHSKFVILSAHKLVFIGDTLSRQAKAADVRSKVTHYSNLLCDLLRGIVATTKAAALQYPSPSAAQDMVDRVKELGHSTQQFRRVLGQLAAA", "length": 968 }, "evidence": [ { "id": "A0A8V0ZT35", "url": "https://omabrowser.org/oma/group/A0A8V0ZT35/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 13, "go_terms": [ { "name": "endothelin receptor signaling pathway", "id": "GO:0086100", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0086100", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZT35", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT35" } ], "pmid": "" }, { "name": "actin filament organization", "id": "GO:0007015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007015", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZT35", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT35" } ], "pmid": "" }, { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZT35", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT35" } ], "pmid": "" }, { "name": "cell surface receptor protein tyrosine kinase signaling pathway", "id": "GO:0007169", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007169", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZT35", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT35" } ], "pmid": "" }, { "name": "integrin-mediated signaling pathway", "id": "GO:0007229", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007229", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZT35", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT35" } ], "pmid": "" }, { "name": "cell migration", "id": "GO:0016477", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016477", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZT35", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT35" } ], "pmid": "" }, { "name": "positive regulation of endothelial cell migration", "id": "GO:0010595", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010595", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZT35", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT35" } ], "pmid": "" }, { "name": "B cell receptor signaling pathway", "id": "GO:0050853", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050853", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZT35", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT35" } ], "pmid": "" }, { "name": "cell chemotaxis", "id": "GO:0060326", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060326", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZT35", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT35" } ], "pmid": "" }, { "name": "vascular endothelial growth factor receptor signaling pathway", "id": "GO:0048010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048010", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZT35", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT35" } ], "pmid": "" }, { "name": "platelet-derived growth factor receptor signaling pathway", "id": "GO:0048008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048008", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZT35", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT35" } ], "pmid": "" }, { "name": "cellular response to hepatocyte growth factor stimulus", "id": "GO:0035729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035729", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZT35", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT35" } ], "pmid": "" }, { "name": "hepatocyte growth factor receptor signaling pathway", "id": "GO:0048012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048012", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZT35", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT35" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZT35", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT35" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZT35", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT35" } ], "pmid": "" }, { "name": "focal adhesion", "id": "GO:0005925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005925", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZT35", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT35" } ], "pmid": "" }, { "name": "actin cytoskeleton", "id": "GO:0015629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015629", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZT35", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT35" } ], "pmid": "" }, { "name": "lamellipodium", "id": "GO:0030027", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030027", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZT35", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT35" } ], "pmid": "" }, { "name": "axon", "id": "GO:0030424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030424", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZT35", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT35" } ], "pmid": "" }, { "name": "ruffle", "id": "GO:0001726", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001726", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZT35", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT35" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "SH3 domain binding", "id": "GO:0017124", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017124", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZT35", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT35" } ], "pmid": "" }, { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZT35", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT35" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 477, "end_pos": 479, "annotation": "n_glycosylation_sequon" }, { "start_pos": 647, "end_pos": 649, "annotation": "n_glycosylation_sequon" }, { "start_pos": 765, "end_pos": 767, "annotation": "n_glycosylation_sequon" }, { "start_pos": 799, "end_pos": 801, "annotation": "n_glycosylation_sequon" }, { "start_pos": 900, "end_pos": 902, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZT35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT35" }, { "id": "PS50002", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50002" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SH3", "eco_id": "ECO_0000259", "start_pos": 12, "end_pos": 74, "start_aa": "Leu", "end_aa": "Gly", "glycosite_overlap": "" } ], 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"PPP1R3D", "type": "recommended", "evidence": [ { "id": "A0A8V0ZT46", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT46" } ] }, { "name": "PPP1R3D", "type": "synonym", "evidence": [ { "id": "XP_004947134", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004947134" } ] } ], "protein_names": [ { "name": "Protein phosphatase 1 regulatory subunit 3D", "type": "synonym", "evidence": [ { "id": "A0A8V0ZT46", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT46/entry#names_and_taxonomy" } ] }, { "name": "protein phosphatase 1 regulatory subunit 3D", "type": "synonym", "evidence": [ { "id": "XP_004947134", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004947134" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052551.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004947134.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004947134", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004947134" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZT46", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT46" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PPP1R3D", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT46", "locus": { "chromosome": "20", "start_pos": 7205464, "end_pos": 7212933, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010024564", "url": "https://www.ensembl.org/id/ENSGALG00010024564" } ] } } ], "crossref": [ { "id": "A0A8V0ZT46", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZT46", "database": "AlphaFoldDB", "categories": [] }, { "id": "419220", "url": "https://www.ncbi.nlm.nih.gov/gene/419220", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR005036", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005036", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038175", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038175", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050782", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050782", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:419220", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419220", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QQPADCM", "url": "https://omabrowser.org/oma/group/QQPADCM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZT46", "url": "https://www.orthodb.org/?gene=A0A8V0ZT46", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12307", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12307", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12307:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12307:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03370", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03370", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004947134", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004947134", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZT46", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT46", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZT46-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT46-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEVRGPRRNRSYLSDLYENMLRAQGAPGQGQQQPSVVRPSSSLCLVSHPPVKVVTQPHQPQSSTFSSCDPALRPIIRRRARSLPTTPERRKRVQCQAPVCQSRMNKVRFADALGLELTEVKVFQKGEDPSIPLHVLSRLSINSDLWYSNLEFTMQCLVPDFQQPADCMDFSARLQEQQVCLERVTSSDLGVSGTIQVCNIAFEKQVSVRYTFNQWKSLHEVCAHWQSSILDKNGQDQVDVFTFFLPVPSFLLQLCSIVQFAARYQVNGQEYWDNNRGKNYSLTCRTHPLKMPRECEESWIHFI", "length": 303, "header": "tr|A0A8V0ZT46-1|A0A8V0ZT46_CHICK Isoform 1 of Protein phosphatase 1 regulatory subunit 3D OS=Gallus gallus OX=9031 GN=PPP1R3D PE=4 SV=1 CANONICAL=A0A8V0ZT46-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZT46-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT46/entry#A0A8V0ZT46-1", "sequence": { "sequence": "MEVRGPRRNRSYLSDLYENMLRAQGAPGQGQQQPSVVRPSSSLCLVSHPPVKVVTQPHQPQSSTFSSCDPALRPIIRRRARSLPTTPERRKRVQCQAPVCQSRMNKVRFADALGLELTEVKVFQKGEDPSIPLHVLSRLSINSDLWYSNLEFTMQCLVPDFQQPADCMDFSARLQEQQVCLERVTSSDLGVSGTIQVCNIAFEKQVSVRYTFNQWKSLHEVCAHWQSSILDKNGQDQVDVFTFFLPVPSFLLQLCSIVQFAARYQVNGQEYWDNNRGKNYSLTCRTHPLKMPRECEESWIHFI", "length": 303, "header": "tr|A0A8V0ZT46-1|A0A8V0ZT46_CHICK Isoform 1 of Protein phosphatase 1 regulatory subunit 3D OS=Gallus gallus OX=9031 GN=PPP1R3D PE=4 SV=1 CANONICAL=A0A8V0ZT46-1" }, "locus": { "chromosome": "20", "start_pos": 7205464, "end_pos": 7205160, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010059919.1", "url": "https://www.ensembl.org/id/ENSGALT00010059919.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036679.1", "url": "https://www.ensembl.org/id/ENSGALP00010036679.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:419220", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419220", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A2AJW4-1", "protein_name": "Protein phosphatase 1 regulatory subunit", "gene_name": "Ppp1r3d", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSKGSGSAPLPSTPGSRKLVPRSLSCLSDMDRRPCRPPGCDPRLRPIIQRRSRSLPTSPERRAKAAGAPGAACGAGCNRQVRVRFADALGLELAQVKVFNAGDDPSVPLHVLSRLAINSDLCCSSQDLEFTLQCLVPDFSPPIETPGFGERLARQLVCLERVTCSDLGISGTVRVRNVAFEKQVTVRYTFSGWRSAHEAVARWRGPAGAEGTEDIFAFGFPVPPFLLELGSQVHFALRYGVAGAEYWDNNDGRDYSLTCRSHALHMPRGECEESWIHFI", "length": 279 }, "evidence": [ { "id": "A0A8V0ZT46", "url": "https://omabrowser.org/oma/group/A0A8V0ZT46/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3ZSF0-1", "protein_name": "Family with sequence similarity 217, member B", "gene_name": "Fam217b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLEGRLPSVSLLSVFFCFQFRWLFSFSEDKGNKEVTSPAVIIRQQIEQEDSEHCREEGRAAAKGCSINAGSSWNQVQPLKISSGKRPSELQGPRVSSQPRSSLLGISQPAADKLVETIPREGRQEQAELSSRYQAASGGRLFLDFHSMEIIKGGADEDSASDLSDSERVAIPPSPFTPPDLNLRAEEIDPVSFSLHPEPSQAESGHCYPDFLPPPFNSWDLRDMAVVLNTECRTEALPRATGLLGKYIDRLLQLEWLQVQTVQGEKARAAKAKLPGAAGGLKSPGRGKLLTSSLSKPLPSPEGISKPGPSRKKGFRHEEAHPSYYAFETLPNSGDGPGRPRLCSQKQAPEPRMEKKKKSSKGPKPQLRAPPCVEGNPAMEANGNIRIPKQSPVLLDPVGSYRASRTQAHVDLKKKGSANNCGCAPSSGEKKLKTNGAKQSTYKLK", "length": 445 }, "evidence": [ { "id": "A0A8V0ZT46", "url": "https://omabrowser.org/oma/group/A0A8V0ZT46/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "protein phosphatase type 1 complex", "id": "GO:0000164", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000164", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZT46", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT46" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein phosphatase 1 binding", "id": "GO:0008157", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008157", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZT46", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT46" } ], "pmid": "" }, { "name": "glycogen binding", "id": "GO:2001069", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2001069", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZT46", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT46" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of glycogen biosynthetic process", "id": "GO:0005979", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005979", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZT46", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT46" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 279, "end_pos": 281, "annotation": "n_glycosylation_sequon" }, { "start_pos": 9, "end_pos": 11, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZT46", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT46" }, { "id": "PS51159", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51159" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CBM21", "eco_id": "ECO_0000259", "start_pos": 171, "end_pos": 283, "start_aa": "Ser", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 279, "end_pos": 281 }, { "start_pos": 9, "end_pos": 11 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZT48-1", "uniprot_ac": "A0A8V0ZT48", "uniprot_id": "A0A8V0ZT48_CHICK", "mass": { "chemical_mass": 566627.0, "monoisotopic_mass": 566627.0 }, "refseq": { "ac": "NP_001152843", "name": "hydrocephalus-inducing protein homolog", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001152843" }, "gene_names": [ { "name": "HYDIN", "type": "recommended", "evidence": [ { "id": "A0A8V0ZT48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT48" } ] }, { "name": "HYDIN2", "type": "synonym", "evidence": [ { "id": "NP_001152843", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001152843" } ] }, { "name": "HYDIN", "type": "synonym", "evidence": [ { "id": "NP_001152843", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001152843" } ] } ], "protein_names": [ { "name": "HYDIN, axonemal central pair apparatus protein", "type": "synonym", "evidence": [ { "id": "A0A8V0ZT48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT48/entry#names_and_taxonomy" } ] }, { "name": "axonemal central pair apparatus protein", "type": "synonym", "evidence": [ { "id": "NP_001152843", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001152843" } ] }, { "name": "hydrocephalus inducing homolog 2", "type": "synonym", "evidence": [ { "id": "NP_001152843", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001152843" } ] }, { "name": "hydrocephalus-inducing protein homolog", "type": "synonym", "evidence": [ { "id": "NP_001152843", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001152843" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## INFERRED REFSEQ: This record is predicted by genome sequence analysis and is not yet supported by experimental evidence. The reference sequence was derived from JAENSK010000247.1. On Sep 10, 2021 this sequence version replaced NP_001152843.2.", "evidence": [ { "database": "RefSeq", "id": "NP_001152843", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001152843" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZT48", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT48" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "HYDIN", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT48", "locus": { "chromosome": "11", "start_pos": 1670304, "end_pos": 1566267, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022845", "url": "https://www.ensembl.org/id/ENSGALG00010022845" } ] } } ], "crossref": [ { "id": "427538", "url": "https://www.ncbi.nlm.nih.gov/gene/427538", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000399", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000399", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033305", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033305", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033768", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033768", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR053879", "url": "https://www.ebi.ac.uk/interpro/entry/IPR053879", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058536", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058536", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:427538", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427538", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PCEWFVQ", "url": "https://omabrowser.org/oma/group/PCEWFVQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZT48", "url": "https://www.orthodb.org/?gene=A0A8V0ZT48", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23053", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23053", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23053:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23053:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF17213", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17213", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22544", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22544", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24507", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24507", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001152843", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001152843", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZT48", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT48", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZT48-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT48-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MATNKLHQSVGSSKSPDGFQNEVVTPCNSKLVTEAEEPVTLTPSAFLKEMSLTTEQRLASTHSTRRPRIVQLLDMSDTSHQKFSSVDLDQTLFQPFPSEVVFQSYIPCEVYEVPLVLRNNDRVPRLVKVVLESSPYFKLISPGDVCRKVAPGMASTFRILFTPEENKDYFHQLTCITEREKFVVPIRAIGARAILDFPDQLNFSVCPVKHSTQRTLLVRNVGNREARYHISTHSPFSVDPSIGTLGIGDTMQVTVEFHPLKTGDHCESLVVHYDTGEDVVTSLYGAAVDVNIRLDRNSLMIAKTYLTLANHRSVVIHNRSEIIAHFQWKAFVTQEEEDQQKLRLCHRLRRQEQDEMDRFIDECVVDPSLQERLSVLSRVFQNHRAKVQGDSMLFSDDVFAIEPVEGDVWPNSSAEINVIFRPREARLYQQTVYCDISGRETRLPLRIRGEGEGPRLRFSFDQLDIGKVFVGSAHSYEAILFNKGAIDALFHMVPPSTALGSCFAFVPREGLIPPGGLQHIHISFCSTILGQFTEEFGVTVHGCPQPVTLTVRGCVIGPTFHFDVPSLCFGDVSFGFPHTLSCRLSNTSLVPMTFSLRIPGDGSGAPSVSSSAQVLDNTHLSWRMGLPAHPKPTEFTVMPCRGTIRAQGTQDVQVTLCSNTVKQYEMALVVDVDGVGKEVLALLLTARCVVPLLRVLSPVVPFGRCFLQHPYQRALTLVNDSDVPGCYGLLPQEHQEGAAVRYSSPAPCGIIQPHSSVEVPVTLQAQVTGKKLTVASVAVFGREGSPLEIHLVSTGEGPVVYVHPSKLNFGRIPVLQDASQTLHLFNQAVIPASFWTEMDGKDSRWRVEPNKGIIPPETEVSLAVIANLNDTKKFQDNLNLFIQNSSTYVIPVQAVGIGTTIVTDKPFAPELNLGPHFSLSPCSYHFKITNKGRRTHQLYWTTEGFAPFRQRDRLPAVGDTKDSSPQGPVFRLRPLRMELMPGRTMDMTLEGFSSTPRVVTERLLCHAIIGSKAGKTQIMQVDVTCEFIAPVLQLSSREITFRVEKQPSDVLTAQHEPLHLKNISSLPLSVVLLVEQPFSLCNAEQQPLSTDTQPLKLKTGEERHLSIRFNPAYKEDLNIRVVERALKIQFLEHPLEEHIAIRGEVYFPNLHMGTTAVDFGCILNDTEDMRYVEMTNCSPLLVRYRWSFLAGSHVSQMRFSPPVPKYFIEPQPEKEEGAPMEPLASADSSSHDMDMKEPDQAVGAAGEPAPEPADADGPLEAQLLPPAVKELESAAEMVSAAETQSLVETKEPAEFVENEPLALGMEEVFNILPLYGELQPGESQQVTFTFFGHANLVVHVTALCEVQGGPTYEVMLSGEASVISYLLDATEIDCGLQLFNEVAEAELTLQNSGKVGFQYQVLSPSDSLLPGVPLVLPSVGYVGPSQEQVLKVFYLPGVPGAFCRTFQIQVGHLEPETITLKGEGSFPRICLDLPRNIRGNEKYENTLQEAREKVEKESRIGETVVPGEATATETPLDDVDTVLDIGLQMQMEEMLVEEHALEQQKLLVSCPPEDSFFDERARRRLLRVQLPEYVLDFGYVILGNIHAHIVNITNTGRLPVSFYADGRVLRDTGFTVELDRVTNLPYCETETFEVRFDPQSANVPLGAADVLLPIKVTGGPTFHLCLRACVTVPSLCISRDSLEFSTVQCGQCQEETIQLYNQFQVPCKWFVTLKEPVKKVDKHLPASVRRKLQQELKAKPCAFEVLPSAGDLAPGQRCNMRVRFTPTEERSYRCELKINICQSSQPLQLQVSGHGLVPQLEFNPPVLELGPLLPYSSGTAETVLVKNPCEFPIEFYSLEFDQQYLAEEQILRVLKDYDCRNTLLLPPRAPGEKLPPEVLEYYQDQKRLQDEQAESRTGGPAGQDNANGEDVQPLLDQGEKHSAGVIHSLSSHYSVIPLSTSDESQSNKVDSKSERGEGEEEDLEKRHGAEHQQGTGSSKEAAGELDDSPVLRAIARHLGVDISPESRAAQSRRGIVIIIHGAPLTGKTSAAVALSRHYGTACLSIDSLVMEAISDRNSSAGLRARELCLRAAIEQSHKETEEAGQSTDPSAPQLGAEPRHSLETSQSSSGDKTSLHSISSRSRASAATGRRKSDNHASQSQKQQLTDPTGSQGSSSSHRFLVLPCVPTQQWLSIGDSAAGEVGLMSCVLPEDVLGAILSERLQLSDCYQGVVFDGLETLFARSMASALLCLLKAVNNRPYIYFVNLFQDYASWKAKEMAAKEQEEREQEEVARREKERLQEMDEEEYDALTEEQKAQFDENILQIQRERRRRMEQLARELEERQRQELERLKEEEELKKKSRRGRRETGKEKDSVSGKKSQPGVRQNATTSTSNTNASTSNRSDTSEGVDKKGSTKEHPDSAVGDKDEKKKWNKAPPTNASPAVPVQPSTTEQEEAKEKALSDSEKMLAMRFKIYEASQKDIAHILSNWDRVQGVLVSSWSQEEAWQRAEEQNTHLSSRRSRKDREKERLEKERQERERQEKLKALEESQAQAGKGAEGSAKGQDVGVPCLDIQVLDAEDAIGKILESGKLPPAEQILDSLGLGPSGPPIPPTAFYSVIRYPEKRVAPTGEALKHFIFIMPEGAVAEEEKKESESLVDAPITPTMKVSEEQLTPTRGKARKEKTEGSREVKKEKRSSVRSKKNLHGTGTGASTHPADVEQSSVDVAPSPGKPIRLSSCRWIVPAHGQVELKVHFTSSVPGQFDQTMNFEVLGTKRLYQLHCRGICAYPTISQDPRVVFRHRRKSKADNDIIFKQYVMSTGVFHFGPLLCGKSRDWYKALPYPSNCEKITILNITPLEAEVHFFFEHDLKADTFIFDPPSMTLKPNEKQELSIWAYPTLAGLVEDKLVCCIKDNPEPVVFRLCCQGVRVELGVSPKHVHFGKLLLHRRDSKQLVLRNLTLLPAAWRLSGLENLGEDFSVSQSEGTVEPCAELSVYLYFKATKALSIKKTIRLEVSDAENILGIVQIENIQIQAEAYDVALSITISKGMDGNVDFGVLRVQDDAKQMLTLKNKGKYEIAYSFTFENADTNIPNLASHFAIQPQRGVLAASERPVHVHLVFHPKAEINIKDKPILKCQVIEPSLCEGGEAIAIIPVKVSAKALFSKYSITPASLIDFGTMVNGTTKTCSFILENKGSLDFRFQIYKAEQDASGLRRKSVNHGMSDHSHEDENVDEVPNSGKQNKQSVQKDTNPLMQARLTLGMFTVYPGFGSIHPGDQQTITVDCQAEPVGTCEEHLSIDISDRDPKDNPLGIPYTLLAESCLPAFVVDDIGSIFEEHRICSNANLCQILQTVQDRGVFITDENKFIFTNVLVGRRATARFKIRNVGKVPCDVVLSIKPISTKPNSRISDIFEVDPVQMCVPSHSHAFATVTFTPQTMQSYQCTFEACLETQASPVAIKTQSLTFDISGEGNLPRVTVLRPVFCNKRGNPLLLFKKLLLGDSEKLPLVLQNSGIIPVQLLIDLLDEAGVFLLKARPTTHCIYQAADTKEDSTGGGKKPHTASLVLYHGESAEFDVLFKPNLPQRVEGQIHLSVVDNPYEETNIQLVGEGYEDDFTLDNIHGLVADSLWQTGGNLEEDVIEAARVDHIQFGDCHIGKPYQVTFTVTNRSQAEAMRFEWLAGTPFHFSPQVGHLHAGCAKDITVTLKSDVALTCQAQPVKCKVSRISFQLPAEQVTDWDDRLHTVKWVDATRGEAATWPVKKKVIETDPEPAHTILEKSSREVELRLSAVIDYADFKLDVDTIQFKETLLFQTRTFPFRMSNTGNVALEYTWMADTGDERATSPAEELLPPGLEGRCLSSVSVASVKLPFGWLGHALEHSSSSLSSPTSLGHVTPLFSVEPRSGTIPAGREQLFQMKFSPVYVGKFKSYMVCSIPNLKPNQKGPEVVVKGKSLMPYCHFELEDSDYITAKRRKPELPEPRGAVLDVNTRVIEFAAIGVGSRNSRTFKVMNPTSSAYSFQWTCQDPEAPPGQRAFFCLTERGQIQPGKKAEIKFEFISRHLDITESFWVFTIPEKSISVLFLLVGHSTEPLVTLDRSHLNLHLLLVGHKEHQTIYMINREKEAFAFAFRESSLFSEGCSTSVKVEPMEGSIAPLSRFPITVAFTPALEGEMVFNLKCDVKRKTEPLSLNIKATGYSMSVSVRCEDSNGGVTELSAQEVNVIDFKEVQLNERAQRTFSIHNNGKFSFTFSWELSGPTAQVQLLSLSPQTGSVQAEGKVDTQLVFHPRKMCSLKDVELTLQISKGPMFTCVFLATVVVPTVYFSTTRLNFGACFIYQAGMPPARQTLAITNKADKDVSLSCLFTNTMHLEVDFPGYILRPGGTVKVPITFYPREVASYHELIPFEINGLCQRTVEVQGKGAEMKVDVVEPHGKVVKLGALSVGQTVKKTVTIANNSVAPLTFKLCFMPIVPELQEDGVLCLHPSSELSLKPKGDIYKVEVIFSPKCRIQPFTEEVMLESSGLLRSLFMVQGSCQGICVSLDQEHLSFGAVVQQSCTSQRITMQNTGDIGVKFKWDVKSFQPDFSISPTKGYISPGMDVPFVVSFHPSKLSPAIRYEGLQCFIQDSEPLCLTLAGCCMETPIVKETLIFSCNVREKHSQTILLSNPSNEPWTVKPVIEGDHWKGPECIHLEGNQQDKPYKITYEPLTMSSEEREHQGSIFFPLPDGTGLYYLLQGTAEEPKCSGTIVREVPCRTPYTELLPISNWLNKPQRFLVVTEILQPEDPVGSSVLHGLEYIDVPGSGKKDYKLTFLSYKEGVFRTMVTFLNEVTEEYLFYMVTFKATASGPIGTVEVSAAVRQNVSSTIKVDNPLAAPVVFDIDCKVPDITVPPHFTVPAQSEANLVFEYQPLKVGESTERLMLHSSNLGSCYYELILKATISKPEKPLYFCTMLGSNQTITTKIMNYNRQKTEYMLQTDCADFQTEKTISMPPACLGGSEVSVEVTYEPCQLGESRATLQLLGPPGGEYSIPLFGLALPPRPQGPFLIKAGGSTSIPFKNIFPQPTAFRYNVENPAFAVRATETLRPKKTIFMAVSFEGSPDGTKTPVSSRLVVSCARADGLGAGISWVFYLRGLPLEK", "length": 5106, "header": "tr|A0A8V0ZT48-1|A0A8V0ZT48_CHICK Isoform 1 of HYDIN, axonemal central pair apparatus protein OS=Gallus gallus OX=9031 GN=HYDIN PE=4 SV=1 CANONICAL=A0A8V0ZT48-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZT48-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT48/entry#A0A8V0ZT48-1", "sequence": { "sequence": "MATNKLHQSVGSSKSPDGFQNEVVTPCNSKLVTEAEEPVTLTPSAFLKEMSLTTEQRLASTHSTRRPRIVQLLDMSDTSHQKFSSVDLDQTLFQPFPSEVVFQSYIPCEVYEVPLVLRNNDRVPRLVKVVLESSPYFKLISPGDVCRKVAPGMASTFRILFTPEENKDYFHQLTCITEREKFVVPIRAIGARAILDFPDQLNFSVCPVKHSTQRTLLVRNVGNREARYHISTHSPFSVDPSIGTLGIGDTMQVTVEFHPLKTGDHCESLVVHYDTGEDVVTSLYGAAVDVNIRLDRNSLMIAKTYLTLANHRSVVIHNRSEIIAHFQWKAFVTQEEEDQQKLRLCHRLRRQEQDEMDRFIDECVVDPSLQERLSVLSRVFQNHRAKVQGDSMLFSDDVFAIEPVEGDVWPNSSAEINVIFRPREARLYQQTVYCDISGRETRLPLRIRGEGEGPRLRFSFDQLDIGKVFVGSAHSYEAILFNKGAIDALFHMVPPSTALGSCFAFVPREGLIPPGGLQHIHISFCSTILGQFTEEFGVTVHGCPQPVTLTVRGCVIGPTFHFDVPSLCFGDVSFGFPHTLSCRLSNTSLVPMTFSLRIPGDGSGAPSVSSSAQVLDNTHLSWRMGLPAHPKPTEFTVMPCRGTIRAQGTQDVQVTLCSNTVKQYEMALVVDVDGVGKEVLALLLTARCVVPLLRVLSPVVPFGRCFLQHPYQRALTLVNDSDVPGCYGLLPQEHQEGAAVRYSSPAPCGIIQPHSSVEVPVTLQAQVTGKKLTVASVAVFGREGSPLEIHLVSTGEGPVVYVHPSKLNFGRIPVLQDASQTLHLFNQAVIPASFWTEMDGKDSRWRVEPNKGIIPPETEVSLAVIANLNDTKKFQDNLNLFIQNSSTYVIPVQAVGIGTTIVTDKPFAPELNLGPHFSLSPCSYHFKITNKGRRTHQLYWTTEGFAPFRQRDRLPAVGDTKDSSPQGPVFRLRPLRMELMPGRTMDMTLEGFSSTPRVVTERLLCHAIIGSKAGKTQIMQVDVTCEFIAPVLQLSSREITFRVEKQPSDVLTAQHEPLHLKNISSLPLSVVLLVEQPFSLCNAEQQPLSTDTQPLKLKTGEERHLSIRFNPAYKEDLNIRVVERALKIQFLEHPLEEHIAIRGEVYFPNLHMGTTAVDFGCILNDTEDMRYVEMTNCSPLLVRYRWSFLAGSHVSQMRFSPPVPKYFIEPQPEKEEGAPMEPLASADSSSHDMDMKEPDQAVGAAGEPAPEPADADGPLEAQLLPPAVKELESAAEMVSAAETQSLVETKEPAEFVENEPLALGMEEVFNILPLYGELQPGESQQVTFTFFGHANLVVHVTALCEVQGGPTYEVMLSGEASVISYLLDATEIDCGLQLFNEVAEAELTLQNSGKVGFQYQVLSPSDSLLPGVPLVLPSVGYVGPSQEQVLKVFYLPGVPGAFCRTFQIQVGHLEPETITLKGEGSFPRICLDLPRNIRGNEKYENTLQEAREKVEKESRIGETVVPGEATATETPLDDVDTVLDIGLQMQMEEMLVEEHALEQQKLLVSCPPEDSFFDERARRRLLRVQLPEYVLDFGYVILGNIHAHIVNITNTGRLPVSFYADGRVLRDTGFTVELDRVTNLPYCETETFEVRFDPQSANVPLGAADVLLPIKVTGGPTFHLCLRACVTVPSLCISRDSLEFSTVQCGQCQEETIQLYNQFQVPCKWFVTLKEPVKKVDKHLPASVRRKLQQELKAKPCAFEVLPSAGDLAPGQRCNMRVRFTPTEERSYRCELKINICQSSQPLQLQVSGHGLVPQLEFNPPVLELGPLLPYSSGTAETVLVKNPCEFPIEFYSLEFDQQYLAEEQILRVLKDYDCRNTLLLPPRAPGEKLPPEVLEYYQDQKRLQDEQAESRTGGPAGQDNANGEDVQPLLDQGEKHSAGVIHSLSSHYSVIPLSTSDESQSNKVDSKSERGEGEEEDLEKRHGAEHQQGTGSSKEAAGELDDSPVLRAIARHLGVDISPESRAAQSRRGIVIIIHGAPLTGKTSAAVALSRHYGTACLSIDSLVMEAISDRNSSAGLRARELCLRAAIEQSHKETEEAGQSTDPSAPQLGAEPRHSLETSQSSSGDKTSLHSISSRSRASAATGRRKSDNHASQSQKQQLTDPTGSQGSSSSHRFLVLPCVPTQQWLSIGDSAAGEVGLMSCVLPEDVLGAILSERLQLSDCYQGVVFDGLETLFARSMASALLCLLKAVNNRPYIYFVNLFQDYASWKAKEMAAKEQEEREQEEVARREKERLQEMDEEEYDALTEEQKAQFDENILQIQRERRRRMEQLARELEERQRQELERLKEEEELKKKSRRGRRETGKEKDSVSGKKSQPGVRQNATTSTSNTNASTSNRSDTSEGVDKKGSTKEHPDSAVGDKDEKKKWNKAPPTNASPAVPVQPSTTEQEEAKEKALSDSEKMLAMRFKIYEASQKDIAHILSNWDRVQGVLVSSWSQEEAWQRAEEQNTHLSSRRSRKDREKERLEKERQERERQEKLKALEESQAQAGKGAEGSAKGQDVGVPCLDIQVLDAEDAIGKILESGKLPPAEQILDSLGLGPSGPPIPPTAFYSVIRYPEKRVAPTGEALKHFIFIMPEGAVAEEEKKESESLVDAPITPTMKVSEEQLTPTRGKARKEKTEGSREVKKEKRSSVRSKKNLHGTGTGASTHPADVEQSSVDVAPSPGKPIRLSSCRWIVPAHGQVELKVHFTSSVPGQFDQTMNFEVLGTKRLYQLHCRGICAYPTISQDPRVVFRHRRKSKADNDIIFKQYVMSTGVFHFGPLLCGKSRDWYKALPYPSNCEKITILNITPLEAEVHFFFEHDLKADTFIFDPPSMTLKPNEKQELSIWAYPTLAGLVEDKLVCCIKDNPEPVVFRLCCQGVRVELGVSPKHVHFGKLLLHRRDSKQLVLRNLTLLPAAWRLSGLENLGEDFSVSQSEGTVEPCAELSVYLYFKATKALSIKKTIRLEVSDAENILGIVQIENIQIQAEAYDVALSITISKGMDGNVDFGVLRVQDDAKQMLTLKNKGKYEIAYSFTFENADTNIPNLASHFAIQPQRGVLAASERPVHVHLVFHPKAEINIKDKPILKCQVIEPSLCEGGEAIAIIPVKVSAKALFSKYSITPASLIDFGTMVNGTTKTCSFILENKGSLDFRFQIYKAEQDASGLRRKSVNHGMSDHSHEDENVDEVPNSGKQNKQSVQKDTNPLMQARLTLGMFTVYPGFGSIHPGDQQTITVDCQAEPVGTCEEHLSIDISDRDPKDNPLGIPYTLLAESCLPAFVVDDIGSIFEEHRICSNANLCQILQTVQDRGVFITDENKFIFTNVLVGRRATARFKIRNVGKVPCDVVLSIKPISTKPNSRISDIFEVDPVQMCVPSHSHAFATVTFTPQTMQSYQCTFEACLETQASPVAIKTQSLTFDISGEGNLPRVTVLRPVFCNKRGNPLLLFKKLLLGDSEKLPLVLQNSGIIPVQLLIDLLDEAGVFLLKARPTTHCIYQAADTKEDSTGGGKKPHTASLVLYHGESAEFDVLFKPNLPQRVEGQIHLSVVDNPYEETNIQLVGEGYEDDFTLDNIHGLVADSLWQTGGNLEEDVIEAARVDHIQFGDCHIGKPYQVTFTVTNRSQAEAMRFEWLAGTPFHFSPQVGHLHAGCAKDITVTLKSDVALTCQAQPVKCKVSRISFQLPAEQVTDWDDRLHTVKWVDATRGEAATWPVKKKVIETDPEPAHTILEKSSREVELRLSAVIDYADFKLDVDTIQFKETLLFQTRTFPFRMSNTGNVALEYTWMADTGDERATSPAEELLPPGLEGRCLSSVSVASVKLPFGWLGHALEHSSSSLSSPTSLGHVTPLFSVEPRSGTIPAGREQLFQMKFSPVYVGKFKSYMVCSIPNLKPNQKGPEVVVKGKSLMPYCHFELEDSDYITAKRRKPELPEPRGAVLDVNTRVIEFAAIGVGSRNSRTFKVMNPTSSAYSFQWTCQDPEAPPGQRAFFCLTERGQIQPGKKAEIKFEFISRHLDITESFWVFTIPEKSISVLFLLVGHSTEPLVTLDRSHLNLHLLLVGHKEHQTIYMINREKEAFAFAFRESSLFSEGCSTSVKVEPMEGSIAPLSRFPITVAFTPALEGEMVFNLKCDVKRKTEPLSLNIKATGYSMSVSVRCEDSNGGVTELSAQEVNVIDFKEVQLNERAQRTFSIHNNGKFSFTFSWELSGPTAQVQLLSLSPQTGSVQAEGKVDTQLVFHPRKMCSLKDVELTLQISKGPMFTCVFLATVVVPTVYFSTTRLNFGACFIYQAGMPPARQTLAITNKADKDVSLSCLFTNTMHLEVDFPGYILRPGGTVKVPITFYPREVASYHELIPFEINGLCQRTVEVQGKGAEMKVDVVEPHGKVVKLGALSVGQTVKKTVTIANNSVAPLTFKLCFMPIVPELQEDGVLCLHPSSELSLKPKGDIYKVEVIFSPKCRIQPFTEEVMLESSGLLRSLFMVQGSCQGICVSLDQEHLSFGAVVQQSCTSQRITMQNTGDIGVKFKWDVKSFQPDFSISPTKGYISPGMDVPFVVSFHPSKLSPAIRYEGLQCFIQDSEPLCLTLAGCCMETPIVKETLIFSCNVREKHSQTILLSNPSNEPWTVKPVIEGDHWKGPECIHLEGNQQDKPYKITYEPLTMSSEEREHQGSIFFPLPDGTGLYYLLQGTAEEPKCSGTIVREVPCRTPYTELLPISNWLNKPQRFLVVTEILQPEDPVGSSVLHGLEYIDVPGSGKKDYKLTFLSYKEGVFRTMVTFLNEVTEEYLFYMVTFKATASGPIGTVEVSAAVRQNVSSTIKVDNPLAAPVVFDIDCKVPDITVPPHFTVPAQSEANLVFEYQPLKVGESTERLMLHSSNLGSCYYELILKATISKPEKPLYFCTMLGSNQTITTKIMNYNRQKTEYMLQTDCADFQTEKTISMPPACLGGSEVSVEVTYEPCQLGESRATLQLLGPPGGEYSIPLFGLALPPRPQGPFLIKAGGSTSIPFKNIFPQPTAFRYNVENPAFAVRATETLRPKKTIFMAVSFEGSPDGTKTPVSSRLVVSCARADGLGAGISWVFYLRGLPLEK", "length": 5106, "header": "tr|A0A8V0ZT48-1|A0A8V0ZT48_CHICK Isoform 1 of HYDIN, axonemal central pair apparatus protein OS=Gallus gallus OX=9031 GN=HYDIN PE=4 SV=1 CANONICAL=A0A8V0ZT48-1" }, "locus": { "chromosome": "11", "start_pos": 1670198, "end_pos": 1566653, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055603.1", "url": "https://www.ensembl.org/id/ENSGALT00010055603.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033687.1", "url": "https://www.ensembl.org/id/ENSGALP00010033687.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2642, "start_aa": "Thr", "end_pos": 2642, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2642", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:427538", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427538", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1LSN6-1", "protein_name": "Hydin, axonemal central pair apparatus protein", "gene_name": "Hydin", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDTAVHEKVDHKKCRECGQRKYFKPASKRLEEPMGTVHRKMAKVISGLQSKVLPPMSPKVVTEEEVNRMMSPSEFLKEMSLTTEQKLASTRIICRPQITELLDMGETTHQKFSRVDLDQALFQPFPSEIIFQNYSPCEVYEVPLVLRNNDKIPRMVKVVEESSPYFKIISPKDIGHKVAPGVPSIFRILFTPEENKDYAHMLTCITEREKFIVPVKARGARAILDFPDELNFSTCPVKYSTQKVLLVRNIGNKDSMFHLKTRSPYSVEPTGGILNVGESMQLEVNFEPQTVGNHSGKLIVIYDTGEMVFVCLYGAAIDVNIRLDKNSLIMERTYISLSNQRSITIHNRTNIIAHFQWKVFATQEEEDKEKHRVCDDLHREEKQETSMILEDCILDPSLRERLSIISRTFENQRKLVQGNSMLFLDHIFTIDPLEGDVWPNSTAEITVYFNPLEARLYQQTVYCDISGREIRLPLRIRGEGMGPKIHFNFELLDIGKVFIGSAHCYEAILSNKGSIDALFNVIPKTSALGACFVFNPKEGIIEPSGVQAVQIAFSSTSLGHFEEEFLIDVNGSPEPVKLTIRGCVIGPTFHFNVPALHFGNVSYGFPHTLTCSLNNTSLVSMTFKLRVRGDGEGMSSIPSYSQDSDSKRRSWINTEISTTKPKEFTITPNSGTIRAQGFAAIKVTLCSNTVQKYELALVVDVEGIGEEVLALLITARCVVPKLQLMTTEVDFGRCFLKYPYEKTIQLVNHDDLPGCYKVLPQIYETSPTMLLSSPSPCGVISPHSTVNIPLALETQVTGAHRSTVYISVFGSQEAPLACHVQSIGEGPVIFIHPTQIDFGNIYVLKDTSRILQLSNQSFIPAEFRARLANKKSLWTVKPSEGSVPAEDDIPLTLTANLNDIVTFKDTVILEIKHSNTYRIPIQATGIGSTIVSDKPFAPELNLGSHFSLDTHYYRFKLTNKGRRVQQLFWMNDDFNPKEKQSKKGSTGSSRRQSKVSQESTDSGNPVFQLHPVRMELYPGQTIDVILEGYSATPKKVKEKLVCQAIVGAQKGKSLLMSVTIICEFIAPVIQLSTRQLIYRLEKKPNMVLEPDYQPLVIKNVTTLPVRMLLSTSGPFFICETDKSLLPATPKPIKLEVDEEKNFLVKFDPSYRHDLNNWVAEEVLSIKYTEHPQVDNLSLRGEVHYPNLCFEVMEVDFGCILNDTEVIRYIMITNCSPLVVKFRWFFLVDDEENQIRFAPCMKPYSAFLSQMESIPATSVTASSLAAPPMPEYTEMDFSDSIKTILMDDEAGPEETKKPMTSAMVSEAIKYSSAGTERSQSQPDYPECLWVYDPDEMLSIGIEEVFDILPLYGVLRPYSNHQISFTFYGHCDIVARAKALCEVEGGPTYEIILKGEASLVNYSFDTKDINYGLQLFDHITEREITLKNIGKVGFEFKVLTNYRSSPRNLLPGMPLILPLSGFIQSNKEQVLKVYYLPGIPEVFQRNFQIQIAHLVPENITLYGEGIFPRISLDLHRNLRGNEKYQHFLEQAKKNIEKEYSKYETVNHYEVITEEIPEEETAELSAHLQMEVERLIVQDYALEHQRGISSSTTEDTYFSHRSCRKLAKVQLPEYILDFGYIVLGDVRTHIIKITNTSHFPVSFHAEKHVLHETGFSTELDRVKNLPYCETETFEVRCDPQGANLSVGNKEVILPIKVSGGPTIHICLQATVTIPSMTLSCNKIEFATIQCGQCMVETIQLSNHLQVPCEWFVYTPKSTNKMDKHIPKYLRRKLRAEMTPKSRIFEIQPTSGVLDPDERANVQVKFMPKEEKFYSQSLMFQIGQSNQKLTLLAQGQGLEPRLEFSPSVLELGPLLPYASGDEAEVIVRNPCSFPIEFYSLEFDQQYLLEEKMLRQLKGYDSYNTLLLPPRNPGEKLPQEVYDYFKEVKKSKEEHMKAKYLENLAQENAEEEEMNTSDQGTASTKRTSLSRGISVTSNMEERHLPTEAKNYPDEDDYEESLEKLTFQTDKMQSTDSHSVEEVGEVESNPVSKAIARHLGIDISAEGRLAKNRKGIAIIVYGTPVSGKTANAISMAKFYNTACLNIDSIVLEALSDSNNVLGIRARELCIRAAIEQSMREAEESAQESSVTQNLGAPARLSTENLGRFTSDLTLLTQEYKIPKSMRGSVMLSKGKTESHWSGSQKQQGQQQQQQQQQQPQQQQQPQQQQQQQHHQHQSETPQISSSPLLGGPTQRRLSVSASIGGETGLMSCVLPDDLLIQILAERIQLSDCFRGVVFDGLDTLFARNAPSALICLLKAIGSREHIYVINMSQDYVAMKAQEKAKKELEETKRQEALAKEKERLQTLDEEEYDALTAEQKIAFDREVRQALRERKKRELERLAREMHEKKLQQELERQKEEDELKRKVKRPKPGPVAKEEPPLKKSQGPTNKQLPSVAKLEMKMESIERKVSVREHGLLEETTRKKKATTEYAFGFPITQEQEESEGDFLKDSDKNLAQKFKVYDTCLKDVQNILMYWDRKQGMMVPHTGPDEIPHEVDDQRQAPSGGGGRKGRKDRERERLEKERAEKERLEREKAERERLEKLRAMEERSDGEGEGEEEHEGKKDLGVPFINIQTPDFEGISWKQALESDKLPKGDQILNILGLGSSGPPIPPPVLFSIISYPAKRQSLVATEILKHFVFVIPPNDDLPLSDEKKDMEGDSDLFLNTIVTKAQEEQPSPPAKGSKQKSKDKTEQARETQKDKRRTYSGRKGLSGGASGNLAPMSDIDQNNFDGEHSQEKFIRLNHFRWIVPPNGEVTLRMHFSSFDVGNYDQTFNFELLGTRRQYQLYCRGVCTYPYICKDPKIVYPQRKKDMKLKEVVVKKYVVSMDKFYFGPLLCGKSRDKYKSSLYPDNMETLTILNDSPMVVEAYFCFQHDVKASTYFLEPVNMTLKPNEKQILNVWAYPTAVGVFEDSIVCCIKENPEPAIFKICCQGIRPEIEVEPRQLHFDRLLLHRKESKSLVLRNVTSLPVAWRISSLEHLGEDFTVSMMQGTMLPKGEFGLQVHFQPSKPVNIKKAIRIEVLDAENLVGVVQIENILIFAESYDIALDITFPKGTEGGLDFGTLRVLEEVKQPLQLKNRGKYEIIFSFTVDSVGILPTNLSSMIWIQPKRGTLASIDKPTTVQVFFRARKEVKVESQPILRCQIIEPALSEGEIIASIPIKFSVNAVYSKFTISPSSIINFGALICGTRKSITFTIENQGIIDFKYALYRLTGESPILQKKATSHMRHGRTRESESFYKPGAPKMAKFSDIVQKDMNIANQARFTHGMFTVYPGFGSVSSGGQQVITVECVADPVGRCEEFLAIDISDRDPRENPAGIPYTLLAEACLPAFVTDNNILIFEEHQICTSPNLYHIQQTIQSGGLFVEDENKFIFCNVLVGHKAKARFKISNVGKISCDVNIIVRPISNKVVNRIIDIFDVDPNKMCIGSRSHAFATVLFTPQAMQTYQCIFEATLDGLPSTLARSRGLVFDIIGEGTLPRVTVIRPTLYNQHGNPLLLFKRLLLGHSEKLPLILKNNGTIPAQLHVDLRDQLGVFSLKGRPTTSYIYIMEENKPNEKVKKAHTASLVVSPGDTAEFDVFFHSNKIGRMTGTIHLTVINNQYEETMIHLVGESYEDDITLDNIHGLINTTSQETSEMSEVIEIAEESAMEDLVTAALLDHIQFGYCHIGISYNVSFTITNHSQANVIRFEWPLLATLSFSPQIGHLHPGCSKDVVVTLKSESPITLKKMCVKCKLSKIMFQLPVDQVPDWDDRMRTVKWVDAPRNTPGNLTTKRKVIETDPEPAHSVVEENYRELRIQFSANVDFASYKCETSEVFFKETLVYQTRVFEFDLVNTGQVLLEFCWISEEVSKIVSFAMPENPGSSQKDQLSQGTGSSLDSALDHWTEASPSPFSVEPSSGFVPVGKTQKLKLKFSPMDIGEFESSLYCQIPNLPLGEQGPLLITKGRSVLPFCHFDLKESDYISGHRRNPELRGPGSGPLEPNTRVIEFTSVGIGGKNLRTFTILNPTNSTYSFCWTSEETESLQNPPAFVCLTEKGIIHPEKKAEIIFQFLPAHLDITEAFWTFSIPEHNISVPFLLVGKTTDPLISLDKSHLNFSSLLIGREARETVKIINKEEQGFNFAFQDSSRYSEGFNNSLIVCPMEGWIPPLSRFPVDIFFTPKQEGDVNFNLICNIKKKAHPLTLNVKAEGYTMNAEVKCRDRMGSTTLLTSTQVNTINFYEVELNECVQCEFNFINTGKFNFSYQAELSGPKFLLQYLDFTPTDNSVDVGQSEPASLSFQPYQKCVLKGLELKIKISHGPTFICNVVGCAVSPAVHFSFTSHNFGTCFIYQAGMPPYKQNLVVTNREETSMSLDCLYTNTPHVEVNFSVDVIKPGKTLEIPITFYPREAINYRELIPFEINGLSQQTVEIKGKGTEMKLLVLDPANRIVKLGAVLPGQVVKKTVSLVNNSLAQLTFNHSIMFSIPELQEAKVITVEPFHSITMKPKEVCKLEITFAPKKRVPPFSEEVFMEWMGLLRPLFLLSGCCQALEISLDQEHLPFGPVVYQTQATRRILMMNTGDVGARFKWDVKKLKPHFTISPEEGYITSGTEIALEVTYHPTEIGKESLYKNILCFIQGGSPLCLTLSGICVGPPVVKEVVNFNCQVRSRHTQTILLSNRSNQTWNLHPIFEGEHWEGPEFITLEAHQQNKPYEITYKPRTMNLENRKHQGTLFFPLPDGTGWLYALHGTAELPKAVANIYREVPCKTPYTELLPISNWLNKPQRFRVIVEILKPEKPDLSVTLKGLDYIDVLSGSKKDYKLNFFAYKEGLYTAKVIFRNEVTNEFLYYTVSFRVTPSGIIKSIQMTSPVRQSVSASIKLENPLPYSVTFSTECKLNDISLPSQFAVPPNSEGTFSFEFQPLKAGEICGRLTLHNGDLGYYQYELLLKALPAPPEKPVHFQTVLGSSQSILAKFTNYTRLKTEYYCKTDCSDFHTEKIINAAPGAQGGTEVSVEVIFEPSHLGETKGILCLSSLIGGEYIIPLFGIALPPKPQGPFLIRAGYNIIIPFKNIFLHATNFSFIVENPAFTIRAAESVRPKKINNITVYFEGNPSGSKTPITTKLIVTCPQCEGTESGIKWVYYLKGITP", "length": 5157 }, "evidence": [ { "id": "A0A8V0ZT48", "url": "https://omabrowser.org/oma/group/A0A8V0ZT48/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q4G0P3-1", "protein_name": "Axonemal central pair apparatus protein HYDIN", "gene_name": "HYDIN", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTSRRLEESMGAVQMGLVNMFKGFQSKVLPPLSPKVVTEEEVNRMLTPSEFLKEMSLTTEQRLAKTRLMCRPQIIELLDMGETTHQKFSGIDLDQALFQPFPSEIIFQNYTPCEVYEVPLILRNNDKIPRLVKVVEESSPYFKVISPKDIGHKVAPGVPSIFRILFTPEENKDYAHTLTCVTEREKFIVPIKARGARAILDFPDKLNFSTCPVKYSTQKILLVRNIGNKNAVFHIKTCRPFSIEPAIGTLNVGESMQLEVEFEPQSVGDHSGRLIVCYDTGEKVFVSLYGAAIDMNIRLDKNSLTIEKTYISLANQRTITIHNRSNIIAHFLWKVFATQQEEDREKYRACDDLIKEEKDETDEFFEECITDPLLREHLSVLSRTFANQRRLVQGDSKLFFNNVFTVEPLEGDVWPNSSAEITVYFNPLEAKLYQQTIYCDILGREIRLPLRIKGEGMGPKIHFNFELLDIGKVFTGSAHCYEAILYNKGSIDALFNMTPPTSALGACFVFSPKEGIIEPSGVQAIQISFSSTILGNFEEEFLVNVNGSPEPVKLTIRGCVIGPTFHFNVPALHFGDVSFGFPHTLICSLNNTSLIPMTYKLRIPGDGLGHKSISYCEQHVDYKRPSWTKEEISSMKPKEFTISPDCGTIRPQGFAAIRVTLCSNTVQKYELALVVDVEGIGEEVLALLITARCVVPALHLVNTEVDFGHCFLKYPYEKTLQLANQDDLPGFYEVQPQVCEEVPTVLFSSPTPSGVISPSSTIHIPLVLETQVTGEHRSTVYISIFGSQDPPLVCHLKSAGEGPVIYVHPNQVDFGNIYVLKDSSRILNLCNQSFIPAFFQAHMAHKKSLWTIEPNEGMVPPETDVQLALTANLNDTLTFKDCVILDIENSSTYRIPVQASGTGSTIVSDKPFAPELNLGAHFSLDTHYYHFKLINKGRRIQQLFWMNDSFRPQAKLSKKGRVKKGHAHVQPQPSGSQEPRDPQSPVFHLHPASMELYPGQAIDVILEGYSATPRIVKEKLVCHAIIGAQKGKSLVMAVNITCEFVAPLIQLSTKQLIYRLEKKPNSILKPDYQPLAIKNISTLPVNLLLSTSGPFFICETDKSLLPATPEPIKLEIDEEKNLLIKFDPSYRNDLNNWVAEEILAIKYVEHPQIDSLDLRGEVHYPNLSFETKELDFGCILNDTELIRYVTITNCSPLVVKFRWFFLVNDEENQIRFVTLPKKPYSAPVSQMESIPATSEAASPPAILVTVESPEMDLNDFVKTVLVDEDARPEEKELRKTKASSVISDEIKISSTEIERIYSSQSQVEDQESLQTCEQNEMLSIGIEEVFDILPLFGVLQPHSSHQISFTFYGHANIIAQAKALCEVEEGPTYEITLKGEASLVNYSFDTKDIHYGLQLFDHVTEREITLTNMGKVGFEFKVLTDHQSSPDNLLPGVPLILPVSGFISSHQEQVLKVYYLPGVPEVFKRSFQIQIAHLDPENITLSGEGIFPQICLDLPRNLTANEKYEMFLNQARKNTDKEYNKCEMLDHFDIITEEVPEDEPAEVSAHLQMEVERLIVQSYVLEHQKTTTPDPMDDPCFSHRSRRKLAKIQLPEYILDFGYIILGEVRTHIIKIINTSHFPVSFHADKRVLHETGFSTELDRVKNLPHCETEIFEVRFDPQGANLPVGSKEVILPIKVVGGPTVHICLQAKVTIPTMTLSRGKVDFATIQCGQCLVETIQLSNHLQVPCEWFVQSQKPVDKLEKHMPKYLRQKLRAELKPKTRIFEIQPISGVLDPGEKSNVQVKFMPKEEKFYSQTLVFQIAQSAQKLTLLARGQGLEPRLEFSPSVLDLGPLLLCAPGDEAEVIVKNPCNFPIEFYSLEFDQQYLIEEKILRKLKGYDSYNTLLLPPRNPGEKLPPELYEYFKEIKKSKEEQMRAKYLENLAQENEEEDITSSDQGTSNSTKRTSLSRGISVTSNLEEWHALLVESKTYLEEEEDEESLEKIIFQTDKLQSIDSHSMEEVGEVENNPVSKAIARHLGIDISAEGRLAKNRKGIAIIIHGTPLSGKSANAVSVAKYYNAACLSIDSIVLEAVANSNNIPGIRARELCIRAAIEQSVKEGEEAAQEAAVGQNVIGQGRLSTDTLGKLASEMTLVAPEIKPGKSVRGSVVITKSKADSHGSGSQKQHHSHQSETPQISSSPLPPGPIHRWLSVSPSVGGETGLMSCVLPDELLVQILAERIQLSDCYRGVVFDGLDTLFAQNAAAALLCLLKAIGSREHIYILNMAQDYAAMKAQEKAKKEQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQALRERKKREQERLAKEMQEKKLQQELERQKEEDELKRRVKKGKQGPIKEEPPMKKSQAANKQVPPLTKVDVKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQEDSEGDNSKDPDKQLAPKFKTYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDDQRQVPLGGRRGRKDRERERLEKERTEKERLEREKAERERLEKLRALEERSDWEGEGEEDHEGKKEKDLGVPFLDIQTPDFEGLSWKQALESDKLPKGEQILDILGLGASGPPIPPPALFSIVSYPVKRPPLTMTDDLEHFVFVIPPSEDISLDEKKEMEIESDFLATTNTTKAQEEQTSSSKGGKQKMKEKIDQVFEIQKDKRHMALNRKVLSGEPAGTISQLSDTDLDNFNGQHSQEKFTRLNHFRWIVPANGEVTLQVHFSSDEFGNFDQTFNFEILGTCCQYQLYCRGICTYPYICQDPKVVFPQRKMDMKTNEVIFKKYVMSTETYYFGPLLCGKSRDKYKSSLFPGNMETLTILNTSLMVVEASFYFQNDVKANTYFLEPNTMVLKPNEKQILNVWAYPTSVGVFEDSIVCCINDNPEPAIFQLSCQGIRPELELEPRQLHFDRLLLHRQESRVVLLRNVTLLPVAWRITSLEHLGDDFTVSLMQGTIPPEAEYGLHLYFQPTKPVNIKKAIRLEVLDAENLLGVVQIENIMVFAEAYDIALDITFPKGAEGGLDFGIVRVTEEAKQPLQLKNRGKYEIAFSFSVDSVGISTPNINSMISVQPKKGSLTPTEKPTNVQVFFHAKKEVKIEHQPVLRCQIIEPNISEGGEIIASIPIKFSANAVYSKYNITPSSVINFGALICGTRKSTTFTIENQGVTDFKFALYKLTGESPIHQKKAASHVRHARSRESESFYKTGSSRAAKFSDTIQKEVTTTGQARFAHGMFTVYPGFGSIPSGGQQVINVDCVADAMGKCEEFIAIDISGRDPAVHPAGILYTLLAEACLPAFVTENNALIFEEHQICTSANLHHILQTIESGGLFVEDENKFIFCNVLVGRQAKARFKISNVGKITCDVNIVVRPISNKPFARIVDIFEVEPSKMCIASHSHAFATVSFTPQIMQNYQCIFEATLDGLPSTLAKSRGLVFDIAGEGNLPRVTVVRPVLHNQYGNPLLLFKRLLLGHSEKLPLILKNNGVLPAQLHVDLQDELGVFSLKGRPTTAYIYITEENKPHVKAKKAHTASLVVSPGDTAEFDVVFHSQKVGRMRGIIHLSVINNQYEETSIHMVGEGYEDDITLDNIHGLVAPTSQEDISISEFTEIIEDNDMEDLVAAALVDHIQFGDCHIGHSYNASFTVTNHSQVNLIRFEWPVSATIAFSPQMGHLHPGCAKDIVVTMKSDVPINLKNMRIRCKLSRIMFQLPADQVPDWDDRMHTVKWVDVPRNMPGTFTTKRKVIETDPEPAHSVLEENYQELQLQISANVDFASYHCQARDVRFKETLVYQTRVFEFDVINSGRVQLEFSWVSEDTSKAVSFAKPDHQGSAQKDQLSQGTMHTGSTLDSTMDHWAEGSPQPFSVEPSSGIVPVGKIQKFKVKFSPLDIGDFESNLFCQIPNLPPGEQGPVLVAKGRSTLPICHFDLKDSDYISGHQRNPELRGSSGGALDPNTRVIEFTTVGIGGKNLRTFTILNPTNSTYSFCWISEEIESLQNPAAFTCLTEKGFIHPEKKAEIVFQFTPFHLGITESSWTFLIPEHNITVPFLLVGKTTEPLISLNKSHLNFSSLLIGREARETVQIINKEEQGFDFSFQDNSRYSEGFSNSLLVCPMEGWIPPLSRFPIDIFFTPKQEGDVNFNLICNVEKKVHPVTLNVKAEGYTMNVEIKCKDRTGSITLLTPNQTNIINFYEVELNECVQCEFNFINTGKFTFSFQAQLCGSKTLLQYLEFSPIDSTVDVGQSVHATLSFQPLKKCVLTDLELIIKISHGPTFMCNISGCAVSPAIHFSFTSYNFGTCFIYQAGMPPYKQTLVITNKEETPMSIDCLYTNTTHLEVNSRVDVVKPGNTLEIPITFYPRESINYQELIPFEINGLSQQTVEIKGKGTKMKILVLDPANRIVKLGAVLPGQVVKRTVSIMNNSLAQLTFNQSILFTIPELQEPKVLTLAPFHNITLKPKEVCKLEVIFAPKKRVPPFSEEVFMECMGLLRPLFLLSGCCQALEISLDQEHIPFGPVVYQTQATRRILMMNTGDVGARFKWDIKKFEPHFSISPEEGYITSGMEVSFEVTYHPTEVGKESLCKNILCYIQGGSPLSLTLSGVCVGPPAVKEVVNFTCQVRSKHTQTILLSNRTNQTWNLHPIFEGEHWEGPEFITLEAHQQNKPYEITYRPRTMNLENRKHQGTLFFPLPDGTGWLYALHGTSELPKAVANIYREVPCKTPYTELLPITNWLNKPQRFRVIVEILKPEKPDLSITMKGLDYIDVLSGSKKDYKLNFFSHKEGTYAAKVIFRNEVTNEFLYYNVSFRVIPSGIIKTIEMVTPVRQVASASIKLENPLPYSVTFSTECRMPDIALPSQFVVPANSEGTFSFEFQPLKAGETFGRLTLHNTDLGYYQYELYLKATPALPEKPVHFQTVLGSSQIILVKFINYTRQRTEYYCRTDCTDFHAEKLINAAPGGQGGTEASVEVLFEPSHLGETKGILILSSLAGGEYIIPLFGMALPPKPQGPFSIRAGYSIIIPFKNVFYHMVTFSIIVDNPAFTIRAGESVRPKKINNITVSFEGNPSGSKTPITTKLTVSCPPGEGSETGVKWVYYLKGITL", "length": 5121 }, "evidence": [ { "id": "A0A8V0ZT48", "url": "https://omabrowser.org/oma/group/A0A8V0ZT48/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q80W93-1", "protein_name": "Axonemal central pair apparatus protein HYDIN", "gene_name": "Hydin", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": 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"length": 5154 }, "evidence": [ { "id": "A0A8V0ZT48", "url": "https://omabrowser.org/oma/group/A0A8V0ZT48/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "axonemal central apparatus assembly", "id": "GO:1904158", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904158", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZT48", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT48" } ], "pmid": "" }, { "name": "cilium movement", "id": "GO:0003341", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003341", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZT48", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT48" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "magnesium ion binding", "id": "GO:0000287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000287", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZT48", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT48" } ], "pmid": "" }, { "name": "thiamine pyrophosphate binding", "id": "GO:0030976", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030976", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZT48", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT48" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "axoneme", "id": "GO:0005930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005930", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZT48", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT48" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1062, "end_pos": 1064, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1164, "end_pos": 1166, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1176, "end_pos": 1178, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1591, "end_pos": 1593, "annotation": 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], "protein_names": [ { "name": "Achaete-scute family bHLH transcription factor 2", "type": "synonym", "evidence": [ { "id": "A0A8V0ZT51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT51/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZT51", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT51" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ASCL2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT51", "locus": { "chromosome": "5", "start_pos": 13281731, "end_pos": 13278518, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010024569", "url": "https://www.ensembl.org/id/ENSGALG00010024569" } ] } } ], "crossref": [ { "id": "A0A8V0ZT51", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZT51", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR011598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036638", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036638", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050283", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050283", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZT51", "url": "https://www.orthodb.org/?gene=A0A8V0ZT51", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23349", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23349", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23349:SF108", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23349:SF108", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00010", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00010", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZT51", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT51", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZT51-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT51-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMPLWCGLRRCPQSGRSRNPKEPEGGGSAGQSSALGGPIVPHNAPTAAAGRGPRRPVHERERRGGVGGQSTAGSAGESGSTAARSALKGLRSLLPTQHVPHGTASKKLSKVETLRSAVEYIRALQRLLDEHDAAAAFPDGRAGRSAGRAAVGESGGGSGYSSASPCSSEESGYEPVLSPEEQELLDFTSWLGSY", "length": 194, "header": "tr|A0A8V0ZT51-1|A0A8V0ZT51_CHICK Isoform 1 of Achaete-scute family bHLH transcription factor 2 OS=Gallus gallus OX=9031 GN=ASCL2 PE=4 SV=1 CANONICAL=A0A8V0ZT51-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZT51-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT51/entry#A0A8V0ZT51-1", "sequence": { "sequence": "MMPLWCGLRRCPQSGRSRNPKEPEGGGSAGQSSALGGPIVPHNAPTAAAGRGPRRPVHERERRGGVGGQSTAGSAGESGSTAARSALKGLRSLLPTQHVPHGTASKKLSKVETLRSAVEYIRALQRLLDEHDAAAAFPDGRAGRSAGRAAVGESGGGSGYSSASPCSSEESGYEPVLSPEEQELLDFTSWLGSY", "length": 194, "header": "tr|A0A8V0ZT51-1|A0A8V0ZT51_CHICK Isoform 1 of Achaete-scute family bHLH transcription factor 2 OS=Gallus gallus OX=9031 GN=ASCL2 PE=4 SV=1 CANONICAL=A0A8V0ZT51-1" }, "locus": { "chromosome": "5", "start_pos": 13280416, "end_pos": 13278717, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010059924.1", "url": "https://www.ensembl.org/id/ENSGALT00010059924.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036684.1", "url": "https://www.ensembl.org/id/ENSGALP00010036684.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "negative regulation of T-helper 17 cell differentiation", "id": "GO:2000320", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000320", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZT51", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT51" } ], "pmid": "" }, { "name": "negative regulation of T-helper 1 cell differentiation", "id": "GO:0045626", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045626", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZT51", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT51" } ], "pmid": "" }, { "name": "positive regulation of T cell migration", "id": "GO:2000406", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000406", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZT51", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT51" } ], "pmid": "" }, { "name": "response to hypoxia", "id": "GO:0001666", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001666", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZT51", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT51" } ], "pmid": "" }, { "name": "stem cell population maintenance", "id": "GO:0019827", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019827", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZT51", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT51" } ], "pmid": "" }, { "name": "negative regulation of T-helper 2 cell differentiation", "id": "GO:0045629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045629", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZT51", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT51" } ], "pmid": "" }, { "name": "T follicular helper cell differentiation", "id": "GO:0061470", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061470", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZT51", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT51" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZT51", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT51" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZT51", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT51" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "protein dimerization activity", "id": "GO:0046983", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046983", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZT51", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT51" } ], "pmid": "" }, { "name": "DNA-binding transcription repressor activity, RNA polymerase II-specific", "id": "GO:0001227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001227", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZT51", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT51" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZT51", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT51" } ], "pmid": "" }, { "name": "E-box binding", "id": "GO:0070888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070888", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZT51", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT51" } ], "pmid": "" }, { "name": "bHLH transcription factor binding", "id": "GO:0043425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043425", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZT51", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT51" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], 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"count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZT52-1", "uniprot_ac": "A0A8V0ZT52", "uniprot_id": "A0A8V0ZT52_CHICK", "mass": { "chemical_mass": 83368.0, "monoisotopic_mass": 83368.0 }, "refseq": {}, "gene_names": [ { "name": "FBXO40", "type": "recommended", "evidence": [ { "id": "A0A8V0ZT52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT52" } ] } ], "protein_names": [ { "name": "F-box protein 40", "type": "synonym", "evidence": [ { "id": "A0A8V0ZT52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT52/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZT52", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT52" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FBXO40", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT52", "locus": { "chromosome": "1", "start_pos": 76824319, "end_pos": 76809060, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021826", "url": "https://www.ensembl.org/id/ENSGALG00010021826" } ] } } ], "crossref": [ { "id": "A0A8V0ZT52", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZT52", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd22175", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22175", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "426341", "url": "https://www.ncbi.nlm.nih.gov/gene/426341", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001293", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001293", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001810", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001810", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031890", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031890", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036047", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036047", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043013", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043013", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZMQ9", "url": "https://www.orthodb.org/?gene=A0A8V0ZMQ9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZMR3", "url": "https://www.orthodb.org/?gene=A0A8V0ZMR3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZT52", "url": "https://www.orthodb.org/?gene=A0A8V0ZT52", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15933", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15933", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15933:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15933:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15965", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15965", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF15966", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15966", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-8951664", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8951664", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-983168", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983168", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZMQ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMQ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMQ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMQ9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMR3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMR3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMR3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMR3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZT52", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT52", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZT52-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT52-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRHFRHDRRALWDGEPFRPAETRPTARRQRLHREGLPLPHRAPKAPPGQHRHCERCFSRHCRAPIEASVSCMVISCRLHCGATFHMCKQEEHQLLCPLEHVPCLNAHYGCPFSMARFKLAKHLQICPASVVCCSMEWNRWPNVDSDTTLHKNIMKENLSEECLDTALALRDQKILFRNLKVADLFPEWRKKEEVREQIEAMDGMEGAVGGLACGSQEGNDQFPELSQCERENLAKDKEGMDLGSYKTWENIFSKELLACQVTGSATSSGKKTEEASKQKASSPCAAVSAEKAKEVPCKAEEPKDQKPEQAAKREMTGLAPWQEGVLERLKKEVGVADYNMYLVHHGGMLIRFGQMAACTPKEKDFVYGNLEAQEVKTVYTFKVPVSYCGKRARLGDVMAHKIPTSDKSVDTSELGINPEELPKANIVTATLLCALEKELKGHEISEARGIDGLFVDFATQTYSFPLEPFSSDAVLADILDENSQPELHVELYTECVTRRHNKSSSAFTFTCSHFFRRDEFASHFKNVHADIQSCLDGWFQLRCPLAYLGCTFVQNHFRPDGHKAKVIYSKLLKTFAIKPEVDTLLAESGTCNFKVDDRGKAKDLLSSLPLEVLKYIAGFLDSFSLSQLSQVSVLMRDICATLLQERGMVLLVWEKKRYSHGGTSWKARRKTWQFSSLFSRVDRWQLSNVVSMSEHLKECPFYKVERKTDPVLLTGMHETPQQVQKTLVSTFKHRV", "length": 735, "header": "tr|A0A8V0ZT52-1|A0A8V0ZT52_CHICK Isoform 1 of F-box protein 40 OS=Gallus gallus OX=9031 GN=FBXO40 PE=4 SV=1 CANONICAL=A0A8V0ZT52-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZMQ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT52/entry#A0A8V0ZMQ9-1", "sequence": { "sequence": "MHRAPKAPPGQHRHCERCFSRHCRAPIEASVSCMVISCRLHCGATFHMCKQEEHQLLCPLEHVPCLNAHYGCPFSMARFKLAKHLQICPASVVCCSMEWNRWPNVDSDTTLHKNIMKENLSEECLDTALALRDQKILFRNLKVADLFPEWRKKEEVREQIEAMDGMEGAVGGLACGSQEGNDQFPELSQCERENLAKDKEGMDLGSYKTWENIFSKELLACQVTGSATSSGKKTEEASKQKASSPCAAVSAEKAKEVPCKAEEPKDQKPEQAAKREMTGLAPWQEGVLERLKKEVGVADYNMYLVHHGGMLIRFGQMAACTPKEKDFVYGNLEAQEVKTVYTFKVPVSYCGKRARLGDVMAHKIPTSDKSVDTSELGINPEELPKANIVTATLLCALEKELKGHEISEARGIDGLFVDFATQTYSFPLEPFSSDAVLADILDENSQPELHVELYTECVTRRHNKSSSAFTFTCSHFFRRDEFASHFKNVHADIQSCLDGWFQLRCPLAYLGCTFVQNHFRPDGHKAKVIYSKLLKTFAIKPEVDTLLAESGTCNFKVDDRGKAKDLLSSLPLEVLKYIAGFLDSFSLSQLSQVSVLMRDICATLLQERGMVLLVWEKKRYSHGGTSWKARRKTWQFSSLFSRVDRWQLSNVVSMSEHLKECPFYKVERKTDPVLLTGMHETPQQVQKTLVSTFKHRV", "length": 697, "header": "tr|A0A8V0ZMQ9-1|A0A8V0ZMQ9_CHICK Computationally mapped isoform of F-box protein 40 OS=Gallus gallus OX=9031 GN=FBXO40 PE=4 SV=1 CANONICAL=A0A8V0ZT52-1" }, "locus": { "chromosome": "1", "start_pos": 76823320, "end_pos": 76818174, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053094.1", "url": "https://www.ensembl.org/id/ENSGALT00010053094.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031979.1", "url": "https://www.ensembl.org/id/ENSGALP00010031979.1" } ] } }, { "isoform_ac": "A0A8V0ZMR3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT52/entry#A0A8V0ZMR3-1", "sequence": { "sequence": 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"database": "Ensembl Transcript", "id": "ENSGALT00010053099.1", "url": "https://www.ensembl.org/id/ENSGALT00010053099.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031984.1", "url": "https://www.ensembl.org/id/ENSGALP00010031984.1" } ] } }, { "isoform_ac": "A0A8V0ZT52-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT52/entry#A0A8V0ZT52-1", "sequence": { "sequence": "MRHFRHDRRALWDGEPFRPAETRPTARRQRLHREGLPLPHRAPKAPPGQHRHCERCFSRHCRAPIEASVSCMVISCRLHCGATFHMCKQEEHQLLCPLEHVPCLNAHYGCPFSMARFKLAKHLQICPASVVCCSMEWNRWPNVDSDTTLHKNIMKENLSEECLDTALALRDQKILFRNLKVADLFPEWRKKEEVREQIEAMDGMEGAVGGLACGSQEGNDQFPELSQCERENLAKDKEGMDLGSYKTWENIFSKELLACQVTGSATSSGKKTEEASKQKASSPCAAVSAEKAKEVPCKAEEPKDQKPEQAAKREMTGLAPWQEGVLERLKKEVGVADYNMYLVHHGGMLIRFGQMAACTPKEKDFVYGNLEAQEVKTVYTFKVPVSYCGKRARLGDVMAHKIPTSDKSVDTSELGINPEELPKANIVTATLLCALEKELKGHEISEARGIDGLFVDFATQTYSFPLEPFSSDAVLADILDENSQPELHVELYTECVTRRHNKSSSAFTFTCSHFFRRDEFASHFKNVHADIQSCLDGWFQLRCPLAYLGCTFVQNHFRPDGHKAKVIYSKLLKTFAIKPEVDTLLAESGTCNFKVDDRGKAKDLLSSLPLEVLKYIAGFLDSFSLSQLSQVSVLMRDICATLLQERGMVLLVWEKKRYSHGGTSWKARRKTWQFSSLFSRVDRWQLSNVVSMSEHLKECPFYKVERKTDPVLLTGMHETPQQVQKTLVSTFKHRV", "length": 735, "header": "tr|A0A8V0ZT52-1|A0A8V0ZT52_CHICK Isoform 1 of F-box protein 40 OS=Gallus gallus OX=9031 GN=FBXO40 PE=4 SV=1 CANONICAL=A0A8V0ZT52-1" }, "locus": { "chromosome": "1", "start_pos": 76823320, "end_pos": 76809163, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053102.1", "url": "https://www.ensembl.org/id/ENSGALT00010053102.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031987.1", "url": "https://www.ensembl.org/id/ENSGALP00010031987.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-8951664", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8951664", "resource": "Reactome", "description": "Neddylation" }, { "id": "R-GGA-983168", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983168", "resource": "Reactome", "description": "Antigen processing: Ubiquitination & Proteasome degradation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZT52", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT52" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZT52", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT52" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZT52", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT52" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 157, "end_pos": 159, "annotation": "n_glycosylation_sequon" }, { "start_pos": 501, "end_pos": 503, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZT52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT52" }, { "id": "PS50181", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50181" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "F-box", "eco_id": "ECO_0000259", "start_pos": 602, "end_pos": 656, "start_aa": "Lys", "end_aa": "Lys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZT52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT52" }, { "id": "PS50145", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50145" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "TRAF-type", "eco_id": "ECO_0000259", "start_pos": 92, "end_pos": 134, "start_aa": "His", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": 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"field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZT58-1", "uniprot_ac": "A0A8V0ZT58", "uniprot_id": "A0A8V0ZT58_CHICK", "mass": { "chemical_mass": 21773.0, "monoisotopic_mass": 21773.0 }, "refseq": {}, "gene_names": [ { "name": "C12orf57", "type": "recommended", "evidence": [ { "id": "A0A8V0ZT58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT58" } ] } ], "protein_names": [ { "name": "Protein C10", "type": "recommended", "evidence": [ { "id": "A0A8V0ZT58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT58/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZT58", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT58" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "C12orf57", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT58", "locus": { "chromosome": "1", "start_pos": 77275873, "end_pos": 77274698, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010023447", "url": "https://www.ensembl.org/id/ENSGALG00010023447" } ] } } ], "crossref": [ { "id": "A0A8V0ZT58", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZT58", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR026317", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026317", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR13463", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13463", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13463:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13463:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14974", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14974", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZT58", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT58", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZT58-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT58-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "EAADLHTARAPRRGFGLWLRRPPIARSGRQHAWKSRGAARTGARNEWLTRPYLGAGLRLARPRAKGFLSVISALLVFVQQVSRPAGSPTVRCNVVLAEVIKAFGAPENVQRMDEARENACNDMGKMLQFLLPVATQIQQDVIKAYGFSSDGEGVLKFARLIKSYESQDPEIASMSGKLKALFLPPMTLPPHGAGIGGVAAS", "length": 201, "header": "tr|A0A8V0ZT58-1|A0A8V0ZT58_CHICK Isoform 1 of Protein C10 OS=Gallus gallus OX=9031 GN=C12orf57 PE=1 SV=1 CANONICAL=A0A8V0ZT58-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZT58-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT58/entry#A0A8V0ZT58-1", "sequence": { "sequence": "EAADLHTARAPRRGFGLWLRRPPIARSGRQHAWKSRGAARTGARNEWLTRPYLGAGLRLARPRAKGFLSVISALLVFVQQVSRPAGSPTVRCNVVLAEVIKAFGAPENVQRMDEARENACNDMGKMLQFLLPVATQIQQDVIKAYGFSSDGEGVLKFARLIKSYESQDPEIASMSGKLKALFLPPMTLPPHGAGIGGVAAS", "length": 201, "header": "tr|A0A8V0ZT58-1|A0A8V0ZT58_CHICK Isoform 1 of Protein C10 OS=Gallus gallus OX=9031 GN=C12orf57 PE=1 SV=1 CANONICAL=A0A8V0ZT58-1" }, "locus": { "chromosome": "1", "start_pos": 77275674, "end_pos": 77274781, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010057130.1", "url": "https://www.ensembl.org/id/ENSGALT00010057130.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034753.1", "url": "https://www.ensembl.org/id/ENSGALP00010034753.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZT58", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT58" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "post-embryonic development", "id": "GO:0009791", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009791", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZT58", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT58" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], 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"MAGPLAQGWGLGVALRSRAALRPLGLLAPPCRGATAPQCRRATGPGEEVLEENPFYGKYRHKIQELRRSSPDVFESRMEKRNEVKKQPVGFSKQSEFVRCMEEKAEGLSTKTSKGGFTRDKTLDSILNVEMVKEKSAEEIEQIWNRYFSAKDTVYAVIPAEKFDLIWKRAQKCPSVRLAEIHSVFLYALPRKEGYEFFVGQWSGTELHFTSLINIQTQGEAAPSQLVLYHYPELQEEKGIVLMTAEMDSKFLVVHEAQCLANQVQLFYATERSETYELVETFNHRSSEFKYMSVIAELEHSGLGKALRPNQVSDKS", "length": 316, "header": "tr|A0A8V0ZT65-1|A0A8V0ZT65_CHICK Isoform 1 of ATP synthase mitochondrial F1 complex assembly factor 1 OS=Gallus gallus OX=9031 GN=ATPAF1 PE=3 SV=1 CANONICAL=A0A8V0ZT65-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZT65-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT65/entry#A0A8V0ZT65-1", "sequence": { "sequence": "MAGPLAQGWGLGVALRSRAALRPLGLLAPPCRGATAPQCRRATGPGEEVLEENPFYGKYRHKIQELRRSSPDVFESRMEKRNEVKKQPVGFSKQSEFVRCMEEKAEGLSTKTSKGGFTRDKTLDSILNVEMVKEKSAEEIEQIWNRYFSAKDTVYAVIPAEKFDLIWKRAQKCPSVRLAEIHSVFLYALPRKEGYEFFVGQWSGTELHFTSLINIQTQGEAAPSQLVLYHYPELQEEKGIVLMTAEMDSKFLVVHEAQCLANQVQLFYATERSETYELVETFNHRSSEFKYMSVIAELEHSGLGKALRPNQVSDKS", "length": 316, "header": "tr|A0A8V0ZT65-1|A0A8V0ZT65_CHICK Isoform 1 of ATP synthase mitochondrial F1 complex assembly factor 1 OS=Gallus gallus OX=9031 GN=ATPAF1 PE=3 SV=1 CANONICAL=A0A8V0ZT65-1" }, "locus": { "chromosome": "8", "start_pos": 21542760, "end_pos": 21534884, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055635.1", "url": "https://www.ensembl.org/id/ENSGALT00010055635.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033702.1", "url": "https://www.ensembl.org/id/ENSGALP00010033702.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:424616", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424616", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A9J7FEP6-1", "protein_name": "ATP synthase mitochondrial F1 complex assembly factor 1 isoform X1", "gene_name": "Atpaf1", "tax_id": 10029, "organism": "Cricetulus griseus", 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This record is derived from a genomic sequence (NC_052577.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040528506", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040528506" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZT67", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT67" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NUDT8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT67", "locus": { "chromosome": "5", "start_pos": 601537, "end_pos": 599489, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021835", "url": "https://www.ensembl.org/id/ENSGALG00010021835" } ] } } ], "crossref": [ { "id": "A0A8V0ZT67", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZT67", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd03426", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03426", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "101748150", "url": "https://www.ncbi.nlm.nih.gov/gene/101748150", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000086", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000086", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015797", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015797", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045121", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045121", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "HYRIWGI", "url": "https://omabrowser.org/oma/group/HYRIWGI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZT67", "url": "https://www.orthodb.org/?gene=A0A8V0ZT67", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12992", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12992", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12992:SF11", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12992:SF11", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00293", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00293", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040528506", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040528506", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZT67", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT67", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZT67-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT67-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRVGSWARGAPHRVTLCGATERRCRRLLAEGAAGGGAEAGAAVLVPLCSVRGRPALLYTLRCSRLRGPYGGDVSFPGGKREAADGGAEGTALREAREELGLKLREESVWGRLRGLPERHGMLVVPVVANLGPLEDLTLSPNPDEVAEVFTLPLEHLLREENQGYTHFRTAGRYGYTLPVFLNGPHRIWGLTAIITELTLELLAPDLYCRKTHVPGRGITAPQKRA", "length": 225, "header": "tr|A0A8V0ZT67-1|A0A8V0ZT67_CHICK Isoform 1 of Nudix hydrolase 8 OS=Gallus gallus OX=9031 GN=NUDT8 PE=1 SV=1 CANONICAL=A0A8V0ZT67-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZT67-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT67/entry#A0A8V0ZT67-1", "sequence": { "sequence": "MRVGSWARGAPHRVTLCGATERRCRRLLAEGAAGGGAEAGAAVLVPLCSVRGRPALLYTLRCSRLRGPYGGDVSFPGGKREAADGGAEGTALREAREELGLKLREESVWGRLRGLPERHGMLVVPVVANLGPLEDLTLSPNPDEVAEVFTLPLEHLLREENQGYTHFRTAGRYGYTLPVFLNGPHRIWGLTAIITELTLELLAPDLYCRKTHVPGRGITAPQKRA", "length": 225, "header": "tr|A0A8V0ZT67-1|A0A8V0ZT67_CHICK Isoform 1 of Nudix hydrolase 8 OS=Gallus gallus OX=9031 GN=NUDT8 PE=1 SV=1 CANONICAL=A0A8V0ZT67-1" }, "locus": { "chromosome": "5", "start_pos": 601368, "end_pos": 599513, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053123.1", "url": "https://www.ensembl.org/id/ENSGALT00010053123.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032002.1", "url": "https://www.ensembl.org/id/ENSGALP00010032002.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "Q9VY79-1", "protein_name": "Nudix hydrolase domain-containing protein", "gene_name": "Dmel\\CG11095", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSLIAQASRTVPQLLLHLNRHLVTSCSSAASATSSKPPDVDQSITADQLLGPESQRRCMEKMRSLPAFPRPKALTPSRREKQTSAVLIALCQERGTNEISLLYTRRSRHLRSHSFQISFPGGRRDDHDSSYVDCALRETEEEIGLPRHRIQVWGEAKQLQLPRTSSIVPVVGVVPDFSLSELRLNWEEVEEAFSVPLTSLMLPKATRHTQFRSGYSGPVFVVDHYRIWGITGYLTHLFLHCLLPPNLLPDCLKTNIKFIRPFKLPPKLPHHREHSAGDPSMRT", "length": 283 }, "evidence": [ { "id": "A0A8V0ZT67", "url": "https://omabrowser.org/oma/group/A0A8V0ZT67/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZT67", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT67" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZT67", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT67" } ], "pmid": "" }, { "name": "coenzyme A diphosphatase activity", "id": "GO:0010945", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010945", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZT67", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT67" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "coenzyme A catabolic process", "id": "GO:0015938", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015938", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZT67", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT67" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZT67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT67" }, { "id": "PS51462", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51462" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Nudix hydrolase", "eco_id": "ECO_0000259", "start_pos": 38, "end_pos": 181, "start_aa": "Glu", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZT68-1", "uniprot_ac": "A0A8V0ZT68", "uniprot_id": "A0A8V0ZT68_CHICK", "mass": { "chemical_mass": 71513.0, "monoisotopic_mass": 71513.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "GB1/RHD3-type G domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8V0ZT68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT68/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZT68", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT68" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT68", "locus": {} } ], "crossref": [ { "id": "A0A8V0ZT68", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZT68", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR003191", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003191", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015894", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015894", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030386", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030386", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036543", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036543", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR10751", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10751", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02263", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02263", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02841", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02841", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-9953170", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9953170", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9968551", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9968551", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZT68", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT68", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZT68-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT68-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEASVPPMSAPLCLVHNQDCRLSLNPAPVVVVTIVGPFRTGKSFLMKRLVQKCTGSLLGNAVQTQTKGIWMWCLPHPCKPGVALVLLDTEGLGDPRKADSCNDAWIFTLALLLSSTLVYNSIHTTGHRMLEYLWLLMDLRVRVRAQAVDTEPADEFARVFPGFVWVVRDFMMESSEQPISGDEYLERILRPQLWLTMRKYNELQRRLRNFFPHHKLVLAQMEVLRDDQLQPQFRQQEEAFCQHIWKEAPVKVLLNSSQVTGRVLARLSALTVVVEAENSTAVEAAVAEYRQGMEQGLVLPTASHDALMAVHRDWKQRAGTFFLSHAFANTRQCYQALLMDKLEAAKEEFCRRNEEASEQRCCAVLRELWGDTELRMKRGDYVVPGGMRLFQEDLKRVLEEYERRPDKGVKAEAVLKEFLRVKGLEMMEMWLDWVDQQCKAVLAEVAAATQTVEKKLEKQLEKQLEEQLEEHRQQQRAELTKMRMVKEKVEQRICILEKQQEAMLAEVAAIKKMAVEKQQEQQQVALAEVTALQEAAEAQLEERWQRWAQQLQEEQNLVLSQRLQELEARLQEGRGCEAAALQQMQEEDQTVPSWRSTLLKFLDKVVVPILIRLVNSVVNNAA", "length": 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Isoform 1 of GB1/RHD3-type G domain-containing protein OS=Gallus gallus OX=9031 GN= PE=3 SV=1 CANONICAL=A0A8V0ZT68-1" }, "locus": { "chromosome": "34", "start_pos": 1205087, "end_pos": 1202052, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010059945.1", "url": "https://www.ensembl.org/id/ENSGALT00010059945.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036705.1", "url": "https://www.ensembl.org/id/ENSGALP00010036705.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-9953170", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9953170", "resource": "Reactome", "description": "GBP-mediated host defense" }, { "id": "R-GGA-9968551", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9968551", "resource": "Reactome", "description": "Regulation of GBP-mediated host defense" } ], "orthologs": [], "go_annotation": { "categories": [ 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"Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZT78", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT78", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZT78-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT78-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A2I5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2I5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A2I5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2I5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MWHCPLPGHLHTPYHPPRYSLRPPHRIPPQYSTPPRSPCHTLYHLTTLCRLPLPFTRGCLCPPQAEGAALFPLPRPRPTAASSSRSWGGGGDRGCPLTEDNAVPSRPLPLPPPTAGGSTEEDCSHRAPRSHAMSAKWRASLLACEGLSGVCLVPTVASKKMMPKQSSKQAEGRERGSSPDVLALRQDGEKSRSRKEEETAEASQPKKSIKKVVVIKQNCSFQLRIHKNFICEQCCGAFRSSYHLKRHILIHTGEKPFECDVCDMRFIQKYHLERHKRVHSGEKPYQCERCMQSFSRTDRLLRHKRMCQGCQTKGPEAQLLL", "length": 321, "header": "tr|A0A8V0ZT78-1|A0A8V0ZT78_CHICK Isoform 1 of Zinc finger protein 740 OS=Gallus gallus OX=9031 GN=ZNF740 PE=3 SV=1 CANONICAL=A0A8V0ZT78-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZT78-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT78/entry#A0A8V0ZT78-1", "sequence": { "sequence": "MWHCPLPGHLHTPYHPPRYSLRPPHRIPPQYSTPPRSPCHTLYHLTTLCRLPLPFTRGCLCPPQAEGAALFPLPRPRPTAASSSRSWGGGGDRGCPLTEDNAVPSRPLPLPPPTAGGSTEEDCSHRAPRSHAMSAKWRASLLACEGLSGVCLVPTVASKKMMPKQSSKQAEGRERGSSPDVLALRQDGEKSRSRKEEETAEASQPKKSIKKVVVIKQNCSFQLRIHKNFICEQCCGAFRSSYHLKRHILIHTGEKPFECDVCDMRFIQKYHLERHKRVHSGEKPYQCERCMQSFSRTDRLLRHKRMCQGCQTKGPEAQLLL", "length": 321, "header": "tr|A0A8V0ZT78-1|A0A8V0ZT78_CHICK Isoform 1 of Zinc finger protein 740 OS=Gallus gallus OX=9031 GN=ZNF740 PE=3 SV=1 CANONICAL=A0A8V0ZT78-1" }, "locus": { "chromosome": "34", "start_pos": 1213212, "end_pos": 1210794, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010059956.1", "url": "https://www.ensembl.org/id/ENSGALT00010059956.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036716.1", "url": "https://www.ensembl.org/id/ENSGALP00010036716.1" } ] } }, { "isoform_ac": "A0A8V1A2I5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT78/entry#A0A8V1A2I5-1", "sequence": { "sequence": "MAQASLLACEGLSGVCLVPTVASKKMMPKQSSKQAEGRERGSSPDVLALRQDGEKSRSRKEEETAEASQPKKSIKKLRIHKNFICEQCCGAFRSSYHLKRHILIHTGEKPFECDVCDMRFIQKYHLERHKRVHSGEKPYQCERCMQVRVGTRGARRSPRRAPHPPTIPQSFSRTDRLLRHKRMCQGCQTKGPEAQLLL", "length": 198, "header": "tr|A0A8V1A2I5-1|A0A8V0ZT78_CHICK Computationally mapped isoform of Zinc finger protein 740 OS=Gallus gallus OX=9031 GN=ZNF740 PE=3 SV=1 CANONICAL=A0A8V0ZT78-1" }, "locus": { "chromosome": "34", "start_pos": 1213212, "end_pos": 1211364, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010059959.1", "url": "https://www.ensembl.org/id/ENSGALT00010059959.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036719.1", "url": "https://www.ensembl.org/id/ENSGALP00010036719.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 114, "start_aa": "Thr", "end_pos": 114, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr114", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZT78", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT78" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZT78", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT78" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZT78", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT78" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 218, "end_pos": 220, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZT78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT78" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 229, "end_pos": 256, "start_aa": "Phe", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 114 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 218, "end_pos": 220 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZT85-1", "uniprot_ac": "A0A8V0ZT85", "uniprot_id": "A0A8V0ZT85_CHICK", "mass": { "chemical_mass": 56469.0, "monoisotopic_mass": 56469.0 }, "refseq": { "ac": "NP_001026673", "name": "dnaJ homolog subfamily C member 7", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026673" }, "gene_names": [ { "name": "DNAJC7", "type": "recommended", "evidence": [ { "id": "A0A8V0ZT85", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT85" } ] }, { "name": "DNAJC7", "type": "synonym", "evidence": [ { "id": "NP_001026673", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026673" } ] } ], "protein_names": [ { "name": "DnaJ homolog subfamily C member 7", "type": "recommended", "evidence": [ { "id": "A0A8V0ZT85", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT85/entry#names_and_taxonomy" } ] }, { "name": "DnaJ (Hsp40) homolog, subfamily C, member 7", "type": "synonym", "evidence": [ { "id": "NP_001026673", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026673" } ] }, { "name": "dnaJ homolog subfamily C member 7", "type": "synonym", "evidence": [ { "id": "NP_001026673", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026673" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ851525.1, BX935875.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000365.1. On Sep 28, 2011 this sequence version replaced NP_001026673.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001026673", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026673" } ] }, { "annotation": "Acts as a co-chaperone regulating the molecular chaperones HSP70 and HSP90 in folding of steroid receptors, such as the glucocorticoid receptor and the progesterone receptor. Proposed to act as a recycling chaperone by facilitating the return of chaperone substrates to early stages of chaperoning if further folding is required. In vitro, induces ATP-independent dissociation of HSP90 but not of HSP70 from the chaperone-substrate complexes. Recruits NR1I3 to the cytoplasm.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZU86", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU86#function" }, { "database": "UniProtKB", "id": "ARBA00053178", "url": "https://www.uniprot.org/uniprotkb/ARBA00053178#function" }, { "database": "UniProtKB", "id": "A0A8V0ZT85", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT85#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZT85", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT85" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "DNAJC7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT85", "locus": { "chromosome": "27", "start_pos": 4737434, "end_pos": 4756835, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010023076", "url": "https://www.ensembl.org/id/ENSGALG00010023076" } ] } } ], "crossref": [ { "id": "A0A8V0ZT85", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZT85", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd06257", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06257", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "428312", "url": "https://www.ncbi.nlm.nih.gov/gene/428312", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001623", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001623", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019734", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019734", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036869", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036869", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:428312", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428312", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KMCLGLD", "url": "https://omabrowser.org/oma/group/KMCLGLD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZT85", "url": "https://www.orthodb.org/?gene=A0A8V0ZT85", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZU86", "url": "https://www.orthodb.org/?gene=A0A8V0ZU86", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZYQ5", "url": "https://www.orthodb.org/?gene=A0A8V0ZYQ5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45188", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45188", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45188:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45188:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00226", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00226", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00515", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00515", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13181", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13181", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13414", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13414", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13432", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13432", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001026673", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026673", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZT85", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT85", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZT85-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT85-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZU86", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU86", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZU86-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU86-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZYQ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYQ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZYQ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYQ5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAAAECDVIMAAPEGPGEPESEEEARREAESFKEQGNAYYAKKDYNEAYNYYTKAIDTCPNNASYYGNRAATLMMLGRFREALGDAQQSVRLDDSFVRGHLREGKCHLSLGNAMAASRCFQRVLELDHKNTQAQQELKNASTVLEYEKIAEVDFEKRDFRKVVFCMDRALEFAPACHRFKILKAECLALLGRYPEAQSVASDILRMDSTNADALYVRGLCLYYEDCIEKAVQFFVQALRMAPDHEKACLACRNAKALKAKKEDGNKAFKEGNYKLAYELYTEALGIDPNNIKTNAKLYCNRGTVNSKLRKLEEAIDDCTNAVKLDETYIKAYLRRAQCYMDTEQYEDAVRDYEKVYQTEKTKEHKQLLKNAQMELKKSKRKDYYKILGVDKNASEDEIKKAYRKRALMHHPDRHSGASAEVQKEEEKKFKEVGEAFTILSDPKKKARYDSGQDLEEDGLNMGDFDANNIFKAFFGGPGGFSFEASGPGNFFFQFG", "length": 496, "header": "tr|A0A8V0ZT85-1|A0A8V0ZT85_CHICK Isoform 1 of DnaJ homolog subfamily C member 7 OS=Gallus gallus OX=9031 GN=DNAJC7 PE=1 SV=1 CANONICAL=A0A8V0ZT85-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZT85-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT85/entry#A0A8V0ZT85-1", "sequence": { "sequence": "MAAAAECDVIMAAPEGPGEPESEEEARREAESFKEQGNAYYAKKDYNEAYNYYTKAIDTCPNNASYYGNRAATLMMLGRFREALGDAQQSVRLDDSFVRGHLREGKCHLSLGNAMAASRCFQRVLELDHKNTQAQQELKNASTVLEYEKIAEVDFEKRDFRKVVFCMDRALEFAPACHRFKILKAECLALLGRYPEAQSVASDILRMDSTNADALYVRGLCLYYEDCIEKAVQFFVQALRMAPDHEKACLACRNAKALKAKKEDGNKAFKEGNYKLAYELYTEALGIDPNNIKTNAKLYCNRGTVNSKLRKLEEAIDDCTNAVKLDETYIKAYLRRAQCYMDTEQYEDAVRDYEKVYQTEKTKEHKQLLKNAQMELKKSKRKDYYKILGVDKNASEDEIKKAYRKRALMHHPDRHSGASAEVQKEEEKKFKEVGEAFTILSDPKKKARYDSGQDLEEDGLNMGDFDANNIFKAFFGGPGGFSFEASGPGNFFFQFG", "length": 496, "header": "tr|A0A8V0ZT85-1|A0A8V0ZT85_CHICK Isoform 1 of DnaJ homolog subfamily C member 7 OS=Gallus gallus OX=9031 GN=DNAJC7 PE=1 SV=1 CANONICAL=A0A8V0ZT85-1" }, "locus": { "chromosome": "27", "start_pos": 4756802, "end_pos": 4741425, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056230.1", "url": "https://www.ensembl.org/id/ENSGALT00010056230.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034038.1", "url": "https://www.ensembl.org/id/ENSGALP00010034038.1" } ] } }, { "isoform_ac": "A0A8V0ZU86-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT85/entry#A0A8V0ZU86-1", "sequence": { "sequence": "MGPSPLSSMLEDAAAPSGREAESFKEQGNAYYAKKDYNEAYNYYTKAIDTCPNNASYYGNRAATLMMLGRFREALGDAQQSVRLDDSFVRGHLREGKCHLSLGNAMAASRCFQRVLELDHKNTQAQQELKNASTVLEYEKIAEVDFEKRDFRKVVFCMDRALEFAPACHRFKILKAECLALLGRYPEAQSVASDILRMDSTNADALYVRGLCLYYEDCIEKAVQFFVQALRMAPDHEKACLACRNAKALKAKKEDGNKAFKEGNYKLAYELYTEALGIDPNNIKTNAKLYCNRGTVNSKLRKLEEAIDDCTNAVKLDETYIKAYLRRAQCYMDTEQYEDAVRDYEKVYQTEKTKEHKQLLKNAQMELKKSKRKDYYKILGVDKNASEDEIKKAYRKRALMHHPDRHSGASAEVQKEEEKKFKEVGEAFTILSDPKKKARYDSGQDLEEDGLNMGDFDANNIFKAFFGGPGGFSFEASGPGNFFFQFG", "length": 487, "header": "tr|A0A8V0ZU86-1|A0A8V0ZU86_CHICK Computationally mapped isoform of DnaJ homolog subfamily C member 7 OS=Gallus gallus OX=9031 GN=DNAJC7 PE=1 SV=1 CANONICAL=A0A8V0ZT85-1" }, "locus": { "chromosome": "27", "start_pos": 4754303, "end_pos": 4741425, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056213.1", "url": "https://www.ensembl.org/id/ENSGALT00010056213.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034027.1", "url": "https://www.ensembl.org/id/ENSGALP00010034027.1" } ] } }, { "isoform_ac": "A0A8V0ZYQ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT85/entry#A0A8V0ZYQ5-1", "sequence": { "sequence": "MAAAAECDVIMAAPEGPGEPESEEEARREAESFKEQGNAYYAKKDYNEAYNYYTKAIDTCPNNASYYGNRAATLMMLGRFREALGDAQQSVRLDDSFVRGHLREGKCHLSLGNAMAASRCFQRVLELDHKNTQAQQEVVFCMDRALEFAPACHRFKILKAECLALLGRYPEAQSVASDILRMDSTNADALYVRGLCLYYEDCIEKAVQFFVQALRMAPDHEKACLACRNAKALKAKKEDGNKAFKEGNYKLAYELYTEALGIDPNNIKTNAKLYCNRGTVNSKLRKLEEAIDDCTNAVKLDETYIKAYLRRAQCYMDTEQYEDAVRDYEKVYQTEKTKEHKQLLKNAQMELKKSKRKDYYKILGVDKNASEDEIKKAYRKRALMHHPDRHSGASAEVQKEEEKKFKEVGEAFTILSDPKKKARYDSGQDLEEDGLNMGDFDANNIFKAFFGGPGGFSFEASGPGNFFFQFG", "length": 471, "header": "tr|A0A8V0ZYQ5-1|A0A8V0ZT85_CHICK Computationally mapped isoform of DnaJ homolog subfamily C member 7 OS=Gallus gallus OX=9031 GN=DNAJC7 PE=1 SV=1 CANONICAL=A0A8V0ZT85-1" }, "locus": { "chromosome": "27", "start_pos": 4756802, "end_pos": 4741425, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056225.1", "url": "https://www.ensembl.org/id/ENSGALT00010056225.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034035.1", "url": "https://www.ensembl.org/id/ENSGALP00010034035.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:428312", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428312", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2K435-1", "protein_name": "DnaJ homolog subfamily C member 7", "gene_name": "Dnajc7", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPFLGGSCGHTAKSGRNRPWAPAPARRPPWTSRDGRPLWPQAEPLVGRRARGSPSGRGAAERLDAPTGSALHRRPPTRLFGPGGKMAATAECDVVMAATEPELLEDEEAKREAESFKEQGNAYYAKKDYNEAYNYYTKAIDMCPKNASYYGNRAATLMMLGRFREALGDAQQSVRLDDSFVRGHLREGKCHLSLGNAMAACRSFQRALELDHKNAQAQQEFKNANAVMEYEKIAEVDFEKRDFRKVVFCMDRALEFAPACHRFKILKAECLAMLGRYPEAQFVASDILRMDSTNADALYVRGLCLYYEDCIEKAVQFFVQALRMAPDHEKACLACRNAKALKAKKEDGNKAFKEGNYKLAYELYTEALGIDPNNIKTNAKLYCNRGTVNSKLKKLEDAIEDCTNAVKLDDTYVKAYLRRAQCYMDTEQFEEAVRDYEKVYQTEKTKEHKQLLKNAQLELKKSKRKDYYKILGVDKNASEDEIKKAYRKRALMHHPDRHSGASAEVQKEEEKKFKEVGEAFTILSDPKKKTRYDSGQDLDEEGMNMGDFDANNIFKAFFGGPGGFSFEASGPGNFYFQFG", "length": 579 }, "evidence": [ { "id": "A0A8V0ZT85", "url": "https://omabrowser.org/oma/group/A0A8V0ZT85/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0R4IFJ1-1", "protein_name": "DnaJ homolog subfamily C member 7", "gene_name": "dnajc7", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGILRTVAEGGAEGGMKASHASLHPPPLYSKMATVDYDSSVDPEMDLTSDEELEREAEGFKEQGNAYYVKKDYAEAFNFYTKAIDLCPKNASYYGNRAATLMMLSRYREALEDSQQAVRLDDSFMKGHMREGKCHLLLGNAMAAIRCLQKVLEREPDNSQAQQEMKNAESILEYERMAEISFEKRDFRMVVFCMDRVLDSASACHRFKVLKAECLALLGRYPEAQSVASDILRMDSTNGDALYVRGLCLYYEDCIDKAVQFFVQALRMAPDHEKARLACRNAKALKAKKEEGNKAFKEGSYEEAYELYTEALTIDPNNIKTNAKLYCNRATVGSKLNKLEQAIEDCTKAIKLDETYIKAYLRRAQCYMDTEQYEEAVRDYEKVYQTEKTKEHKNLLKNAQLELKKSKRKDYYKVLGVDKNATEDEIKKAYRKRALMHHPDRHSGASAEVQKEEEKKFKEVGEAFTVLSDPKKKTRYDSGHDLEDDDMNMDFDANNIFKAFFGGPGGFSFEASGPGNFFFQFG", "length": 522 }, "evidence": [ { "id": "A0A8V0ZT85", "url": "https://omabrowser.org/oma/group/A0A8V0ZT85/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8C2MY28-1", "protein_name": "DnaJ homolog subfamily C member 7", "gene_name": "Dnajc7", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAATAECDVVMAGTEPELLEDEEAKREAESFKEQGNAYYAKKDYNEAYNYYTKAIDMCPKNASYYGNRAATLMMLGRFREALGDAQQSVRLDDSFVRGHLREGKCHLSLGNAMAACRSFQRALELDHKNAQAQQEFKNANAVMEYEKIAESDFEKRDFRKVVFCMDRALEFAPACHRFKILKAECLAMLGRYPEAQFVASDILRMDSTNADALYVRGLCLYYEDCIEKAVQFFVQALRMAPDHEKACVACRNAKALKAKKEDGNKAFKEGNYKLAYELYTEALGIDPNNIKTNAKLYCNRGTVNSKLRKLDDAIDDCTNAVKLDDTYIKAYLRRAQCYMDTEQYEEAVRDYEKVYQTEKTKEHKQLLKNAQLELKKSKRKDYYKILGVDKNASEDEIKKAYRKRALMHHPDRHSGASAEVQKEEEKKFKEVGEAFTILSDPKKKTRYDSGQDLDEEGMNMGDFDANNIFKAFFGGPGGFSFEASGPGNFFFQFG", "length": 494 }, "evidence": [ { "id": "A0A8V0ZT85", "url": "https://omabrowser.org/oma/group/A0A8V0ZT85/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q99615-1", "protein_name": "DnaJ homolog subfamily C member 7", "gene_name": "DNAJC7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAAAECDVVMAATEPELLDDQEAKREAETFKEQGNAYYAKKDYNEAYNYYTKAIDMCPKNASYYGNRAATLMMLGRFREALGDAQQSVRLDDSFVRGHLREGKCHLSLGNAMAACRSFQRALELDHKNAQAQQEFKNANAVMEYEKIAETDFEKRDFRKVVFCMDRALEFAPACHRFKILKAECLAMLGRYPEAQSVASDILRMDSTNADALYVRGLCLYYEDCIEKAVQFFVQALRMAPDHEKACIACRNAKALKAKKEDGNKAFKEGNYKLAYELYTEALGIDPNNIKTNAKLYCNRGTVNSKLRKLDDAIEDCTNAVKLDDTYIKAYLRRAQCYMDTEQYEEAVRDYEKVYQTEKTKEHKQLLKNAQLELKKSKRKDYYKILGVDKNASEDEIKKAYRKRALMHHPDRHSGASAEVQKEEEKKFKEVGEAFTILSDPKKKTRYDSGQDLDEEGMNMGDFDPNNIFKAFFGGPGGFSFEASGPGNFFFQFG", "length": 494 }, "evidence": [ { "id": "A0A8V0ZT85", "url": "https://omabrowser.org/oma/group/A0A8V0ZT85/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9QYI3-1", "protein_name": "DnaJ homolog subfamily C member 7", "gene_name": "Dnajc7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAATAECDVVMAATEPELLEDEDAKREAESFKEQGNAYYAKKDYNEAYNYYTKAIDMCPNNASYYGNRAATLMMLGRFREALGDAQQSVRLDDSFVRGHLREGKCHLSLGNAMAACRSFQRALELDHKNAQAQQEFKNANAVMEYEKIAEVDFEKRDFRKVVFCMDRALEFAPACHRFKILKAECLAMLGRYPEAQFVASDILRMDSTNADALYVRGLCLYYEDCIEKAVQFFVQALRMAPDHEKACVACRNAKALKAKKEDGNKAFKEGNYKLAYELYTEALGIDPNNIKTNAKLYCNRGTVNSKLRQLEDAIEDCTNAVKLDDTYIKAYLRRAQCYMDTEQFEEAVRDYEKVYQTEKTKEHKQLLKNAQLELKKSKRKDYYKILGVDKNASEDEIKKAYRKRALMHHPDRHSGASAEVQKEEEKKFKEVGEAFTILSDPKKKTRYDSGQDLDEEGMNMGDFDANNIFKAFFGGPGGFSFEASGPGNFYFQFG", "length": 494 }, "evidence": [ { "id": "A0A8V0ZT85", "url": "https://omabrowser.org/oma/group/A0A8V0ZT85/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9V3W1-1", "protein_name": "Tetratricopeptide repeat protein 2, isoform A", "gene_name": "Tpr2", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDDEVIEISDSEREETSSNSEMDVEITTEQPTIDVKAEQIVPKDAATIAEEKKKLGNDQYKAQNYQNALKLYTDAISLCPDSAAYYGNRAACYMMLLNYNSALTDARHAIRIDPGFEKAYVRVAKCCLALGDIIGTEQAVKMVNELNSLSTAVAAEQTAAQKLRQLEATIQANYDTKSYRNVVFYLDSALKLAPACLKYRLLKAECLAFLGRCDEALDIAVSVMKLDTTSADAIYVRGLCLYYTDNLDKGILHFERALTLDPDHYKSKQMRSKCKQLKEMKENGNMLFKSGRYREAHVIYTDALKIDEHNKDINSKLLYNRALVNTRIGNLREAVADCNRVLELNSQYLKALLLRARCYNDLEKFEESVADYETALQLEKTPEIKRMLREAKFALKKSKRKDYYKILGIGRNASDDEIKKAYRKKALVHHPDRHANSSAEERKEEELKFKEVGEAYAILSDAHKKSRYDSGQDIEEQEQADFDPNQMFRTFFQFNGGGRNNSSFNFEF", "length": 508 }, "evidence": [ { "id": "A0A8V0ZT85", "url": "https://omabrowser.org/oma/group/A0A8V0ZT85/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZT85", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT85" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZT85", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT85" } ], "pmid": "" }, { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZT85", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT85" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZT85", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT85" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "heat shock protein binding", "id": "GO:0031072", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031072", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZT85", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT85" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "protein folding", "id": "GO:0006457", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006457", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZT85", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT85" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 140, "end_pos": 142, "annotation": "n_glycosylation_sequon" }, { "start_pos": 393, "end_pos": 395, "annotation": "n_glycosylation_sequon" }, { "start_pos": 63, "end_pos": 65, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZT85", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT85" }, { "id": "PS50076", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50076" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "J", "eco_id": "ECO_0000259", "start_pos": 383, "end_pos": 453, "start_aa": "Asp", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 140, "end_pos": 142 }, { "start_pos": 393, "end_pos": 395 }, { "start_pos": 63, "end_pos": 65 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZTA5-1", "uniprot_ac": "A0A8V0ZTA5", "uniprot_id": "A0A8V0ZTA5_CHICK", "mass": { "chemical_mass": 20957.0, "monoisotopic_mass": 20957.0 }, "refseq": { "ac": "NP_001185571", "name": "phosphatidylethanolamine-binding protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001185571" }, "gene_names": [ { "name": "PEBP1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZTA5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTA5" } ] }, { "name": "PBP", "type": "synonym", "evidence": [ { "id": "NP_001185571", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001185571" } ] }, { "name": "PEBP1", "type": "synonym", "evidence": [ { "id": "NP_001185571", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001185571" } ] } ], "protein_names": [ { "name": "Phosphatidylethanolamine-binding protein 1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZTA5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTA5/entry#names_and_taxonomy" } ] }, { "name": "HCNPpp", "type": "synonym", "evidence": [ { "id": "A0A8V0ZTA5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTA5/entry#names_and_taxonomy" } ] }, { "name": "phosphatidylethanolamine-binding protein 1", "type": "synonym", "evidence": [ { "id": "NP_001185571", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001185571" } ] }, { "name": "prostatic binding protein", "type": "synonym", "evidence": [ { "id": "NP_001185571", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001185571" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: CN222635.1, HAEK01000013.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992683 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CN222635.1 and JAENSK010000260.1. On Oct 31, 2010 this sequence version replaced XP_415283.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001185571", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001185571" } ] }, { "annotation": "HCNP may be involved in the function of the presynaptic cholinergic neurons of the central nervous system. HCNP increases the production of choline acetyltransferase but not acetylcholinesterase. Seems to be mediated by a specific receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTA5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTA5#function" }, { "database": "UniProtKB", "id": "ARBA00037110", "url": "https://www.uniprot.org/uniprotkb/ARBA00037110#function" }, { "database": "UniProtKB", "id": "A0A8V0ZVB9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVB9#function" } ] }, { "annotation": "Newcastle disease virus infection represses RKIP expression thereby promoting virus replication.", "evidence": [ { "database": "RefSeq", "id": "NP_001185571", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001185571" }, { "database": "PubMed", "id": "26297355", "url": "https://glygen.org/publication/PubMed/26297355" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTA5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTA5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PEBP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTA5", "locus": { "chromosome": "15", "start_pos": 9896730, "end_pos": 9898726, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010023499", "url": "https://www.ensembl.org/id/ENSGALG00010023499" } ] } } ], "crossref": [ { "id": "A0A8V0ZTA5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZTA5", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00866", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00866", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "416990", "url": "https://www.ncbi.nlm.nih.gov/gene/416990", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001858", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001858", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008914", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008914", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035810", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035810", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036610", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036610", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416990", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416990", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QEVICYE", "url": "https://omabrowser.org/oma/group/QEVICYE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZTA5", "url": "https://www.orthodb.org/?gene=A0A8V0ZTA5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZVB9", "url": "https://www.orthodb.org/?gene=A0A8V0ZVB9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11362", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11362", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11362:SF151", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11362:SF151", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01161", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01161", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-5675221", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5675221", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001185571", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001185571", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZTA5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTA5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZTA5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTA5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZVB9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVB9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZVB9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVB9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPVELGLWDGPLSLSEVEQKPAHPLRVKYGSVEIDELGKVLTPTQVQHRPTSIEWDGCDPQKLYTLVLTDPDAPSRKDPKFREWHHFLVTNMKGNDVGSGTVLSDYVGSGPPKGTGLHRYVWLVYEQPKQLTCNEPILSNRSGDKRGKFKVAAFRSKYGLGVPVAGTCYQAEWDDYVPKLYEQLSGK", "length": 187, "header": "tr|A0A8V0ZTA5-1|A0A8V0ZTA5_CHICK Isoform 1 of Phosphatidylethanolamine-binding protein 1 OS=Gallus gallus OX=9031 GN=PEBP1 PE=1 SV=1 CANONICAL=A0A8V0ZTA5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZTA5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTA5/entry#A0A8V0ZTA5-1", "sequence": { "sequence": "MPVELGLWDGPLSLSEVEQKPAHPLRVKYGSVEIDELGKVLTPTQVQHRPTSIEWDGCDPQKLYTLVLTDPDAPSRKDPKFREWHHFLVTNMKGNDVGSGTVLSDYVGSGPPKGTGLHRYVWLVYEQPKQLTCNEPILSNRSGDKRGKFKVAAFRSKYGLGVPVAGTCYQAEWDDYVPKLYEQLSGK", "length": 187, "header": "tr|A0A8V0ZTA5-1|A0A8V0ZTA5_CHICK Isoform 1 of Phosphatidylethanolamine-binding protein 1 OS=Gallus gallus OX=9031 GN=PEBP1 PE=1 SV=1 CANONICAL=A0A8V0ZTA5-1" }, "locus": { "chromosome": "15", "start_pos": 9898697, "end_pos": 9897371, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010057232.1", "url": "https://www.ensembl.org/id/ENSGALT00010057232.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034804.1", "url": "https://www.ensembl.org/id/ENSGALP00010034804.1" } ] } }, { "isoform_ac": "A0A8V0ZVB9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTA5/entry#A0A8V0ZVB9-1", "sequence": { "sequence": "MPVEQKPAHPLRVKYGSVEIDELGKVLTPTQVQHRPTSIEWDGCDPQKLYTLVLTDPDAPSRKDPKFREWHHFLVTNMKGNDVGSGTVLSDYVGSGPPKGTGLHRYVWLVYEQPKQLTCNEPILSNRSGDKRGKFKVAAFRSKYGLGVPVAGTCYQAEWDDYVPKLYEQLSGK", "length": 173, "header": "tr|A0A8V0ZVB9-1|A0A8V0ZTA5_CHICK Computationally mapped isoform of Phosphatidylethanolamine-binding protein 1 OS=Gallus gallus OX=9031 GN=PEBP1 PE=1 SV=1 CANONICAL=A0A8V0ZTA5-1" }, "locus": { "chromosome": "15", "start_pos": 9898697, "end_pos": 9897371, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010057236.1", "url": "https://www.ensembl.org/id/ENSGALT00010057236.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034806.1", "url": "https://www.ensembl.org/id/ENSGALP00010034806.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Expression of Raf kinase inhibitor protein is downregulated in response to Newcastle disease virus infection to promote viral replication.", "journal": "The Journal of general virology", "date": "2015-09", "authors": "Yin Renfu, Liu Xinxin, Bi Yuhai, Xie Guangyao, Zhang Pingze, Meng Xin, Ai Lili, Xu Rongyi, Sun Yuzhang, Stoeger Tobias, Ding Zhuang", "evidence": [ { "database": "RefSeq", "id": "NP_001185571", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001185571" } ], "reference": [ { "type": "PubMed", "id": "26297355", "url": "https://glygen.org/publication/PubMed/26297355" } ] } ], "pathway": [ { "id": "gga:416990", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416990", "resource": "KEGG Pathway" }, { "id": "R-GGA-5675221", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5675221", "resource": "Reactome", "description": "Negative regulation of MAPK pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1TTH9-1", "protein_name": "Phosphatidylethanolamine-binding protein 1", "gene_name": "PEBP1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPVDLGKWSGPLSLQEVDERPQHPLQVKYGGAEVDELGKVLTPTQVKSRPTSITWDGLNPDKLYTLVLTDPDAPSRKDPKYREWHHFLVVNMKGNDISSGTVLSDYVGSGPPKGTGLHRYVWLVYEQDGPLKCDEPILSNRSGDHRGKFKVASFRKKYQLGAPVAGTCYQAEWDDYVPKLYEQLSGK", "length": 187 }, "evidence": [ { "id": "A0A8V0ZTA5", "url": "https://omabrowser.org/oma/group/A0A8V0ZTA5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3GU60-1", "protein_name": "Phosphatidylethanolamine-binding protein 1", "gene_name": "Pebp1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MPADISQWSGPLSLQEVDERPQHALRVAYAGVEVDELGKVLTPTQVKNRPSSISWDGLDPGKLYTLVLTDPDAPSRKDPKFREWHHFLVVNMKGNDISSGKVLSDYVGSGPPSGTGLHRYVWLVYEQDKPLNCDEPILSNRSGDHRGKFKVAAFRKKYHLGAPVAGTCYQAEWDDYVPKLYEQLSGK", "length": 187 }, "evidence": [ { "id": "A0A8V0ZTA5", "url": "https://omabrowser.org/oma/group/A0A8V0ZTA5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P13696-1", "protein_name": "Phosphatidylethanolamine-binding protein 1", "gene_name": "PEBP1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPVDLSKWSGPLSLQEVDERPQHPLQVKYGGAEVDELGKVLTPTQVKNRPTSITWDGLDPGKLYTLVLTDPDAPSRKDPKYREWHHFLVVNMKGNNISSGTVLSDYVGSGPPKGTGLHRYVWLVYEQEGPLKCDEPILSNRSGDHRGKFKVASFRKKYELGAPVAGTCYQAEWDDYVPKLYEQLSGK", "length": 187 }, "evidence": [ { "id": "A0A8V0ZTA5", "url": "https://omabrowser.org/oma/group/A0A8V0ZTA5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P30086-1", "protein_name": "Phosphatidylethanolamine-binding protein 1", "gene_name": "PEBP1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPVDLSKWSGPLSLQEVDEQPQHPLHVTYAGAAVDELGKVLTPTQVKNRPTSISWDGLDSGKLYTLVLTDPDAPSRKDPKYREWHHFLVVNMKGNDISSGTVLSDYVGSGPPKGTGLHRYVWLVYEQDRPLKCDEPILSNRSGDHRGKFKVASFRKKYELRAPVAGTCYQAEWDDYVPKLYEQLSGK", "length": 187 }, "evidence": [ { "id": "A0A8V0ZTA5", "url": "https://omabrowser.org/oma/group/A0A8V0ZTA5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P70296-1", "protein_name": "Phosphatidylethanolamine-binding protein 1", "gene_name": "Pebp1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAADISQWAGPLCLQEVDEPPQHALRVDYAGVTVDELGKVLTPTQVMNRPSSISWDGLDPGKLYTLVLTDPDAPSRKDPKFREWHHFLVVNMKGNDISSGTVLSDYVGSGPPSGTGLHRYVWLVYEQEQPLSCDEPILSNKSGDNRGKFKVETFRKKYNLGAPVAGTCYQAEWDDYVPKLYEQLSGK", "length": 187 }, "evidence": [ { "id": "A0A8V0ZTA5", "url": "https://omabrowser.org/oma/group/A0A8V0ZTA5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q54QK0-1", "protein_name": "Phosphatidylethanolamine-binding protein PEBP", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "METVIKALAENKISDVISFTPKKLLTVKYNGKELNINDTLTPTIVQNKPHVSWDAKNDELYTLIFDDPDAPTRSDPKFGQWKHWLVTNIKGNDISTGQELAKYIGSGPPPKTGLHRYIFILCKQPGTENIEFKGEHILPLSAELRNNWNAETFIKKWNLEPEAINFYQAEYDDYVPQLYAKLGETQDKPVEIK", "length": 193 }, "evidence": [ { "id": "A0A8V0ZTA5", "url": "https://omabrowser.org/oma/group/A0A8V0ZTA5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9S7R5-1", "protein_name": "Protein TWIN SISTER of FT", "gene_name": "TSF", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSLSRRDPLVVGSVVGDVLDPFTRLVSLKVTYGHREVTNGLDLRPSQVLNKPIVEIGGDDFRNFYTLVMVDPDVPSPSNPHQREYLHWLVTDIPATTGNAFGNEVVCYESPRPPSGIHRIVLVLFRQLGRQTVYAPGWRQQFNTREFAEIYNLGLPVAASYFNCQRENGCGGRRT", "length": 175 }, "evidence": [ { "id": "A0A8V0ZTA5", "url": "https://omabrowser.org/oma/group/A0A8V0ZTA5/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "serine-type endopeptidase inhibitor activity", "id": "GO:0004867", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004867", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTA5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTA5" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTA5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTA5" } ], "pmid": "" }, { "name": "lipid binding", "id": "GO:0008289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008289", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTA5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTA5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTA5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTA5" } ], "pmid": "" }, { "name": "cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTA5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTA5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "negative regulation of MAPK cascade", "id": "GO:0043409", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043409", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTA5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTA5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 140, "end_pos": 142, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], 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This record is derived from a genomic sequence (NC_052551.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_003642494.3. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003642494", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642494" } ] }, { "annotation": "Adapter protein, which negatively regulates T-cell receptor (TCR) signaling. Inhibits T-cell antigen-receptor induced activation of nuclear factor of activated T-cells. 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"table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZTB3-1", "uniprot_ac": "A0A8V0ZTB3", "uniprot_id": "A0A8V0ZTB3_CHICK", "mass": { "chemical_mass": 57486.0, "monoisotopic_mass": 57486.0 }, "refseq": { "ac": "XP_025001379", "name": "spermatogenesis-associated serine-rich protein 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025001379" }, "gene_names": [ { "name": "SPATS2", "type": "recommended", "evidence": [ { "id": "A0A8V0ZTB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTB3" } ] }, { "name": "SPATS2", "type": "synonym", "evidence": [ { "id": "XP_025001379", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025001379" } ] } ], "protein_names": [ { "name": "Spermatosis associated serine rich 2", "type": "synonym", "evidence": [ { "id": "A0A8V0ZTB3", "database": "UniProtKB", "url": 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This record is derived from a genomic sequence (NC_052565.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_025001379.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_025001379", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025001379" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTB3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTB3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SPATS2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTB3", "locus": { "chromosome": "34", "start_pos": 1838387, "end_pos": 1860171, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010023096", "url": "https://www.ensembl.org/id/ENSGALG00010023096" } ] } } ], "crossref": [ { "id": "A0A8V0ZTB3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZTB3", "database": "AlphaFoldDB", "categories": [] }, { "id": "426663", "url": "https://www.ncbi.nlm.nih.gov/gene/426663", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR009060", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009060", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009816", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009816", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:426663", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:426663", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RNGPWYQ", "url": "https://omabrowser.org/oma/group/RNGPWYQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZTB3", "url": "https://www.orthodb.org/?gene=A0A8V0ZTB3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15623", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15623", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15623:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15623:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07139", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07139", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_025001379", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025001379", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZTB3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTB3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZTB3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTB3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSKKQNPKDPSGFIFDVQSNTVMAQGGTFENMKEKINAVRAIVPNRSNNEIVLVLQHFDNCVDKTVQAFMEGNASEVLKEWTVTGKKKNKKKKTKPKPQAEASPGPADPRKLVSTGEEQSANSEKGGINGFHVNGCAHDTESVDSLSEGLDALSIDARELEDCEPAVPDMPERTVPQLENGIADLDTKSLTVHPAQSPSSLRQRPDQHSASRSGSRPTASTSLPAVRLENVPFSPANKKLGSNIEKSVKDLQRCTVSLARYRVVVKEEMDASIKKMKQVFAELQSSLMDREVALLAEMDKVKAEAMEILMSRQKKAEALKKMTDVAVRMSEEQLIELRADIKHFVSERKYDEELGRVARFTCDLDALKKSIAAFGQVSHPKNSYSTRSRCSSVTAVSPSSPSNASAPSSPACASAISLTTVSKKPPSSVEAAVEGAGSHPPQPHREAAPGNRRPGPPGPPGSRPQSHTAPPPARRPGGPRHRSGAGPALGRHQSSPGSPHQMQPPEPGPAAGAAATHSKGLPQRKPRASRQEGASS", "length": 536, "header": "tr|A0A8V0ZTB3-1|A0A8V0ZTB3_CHICK Isoform 1 of Spermatosis associated serine rich 2 OS=Gallus gallus OX=9031 GN=SPATS2 PE=1 SV=1 CANONICAL=A0A8V0ZTB3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZTB3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTB3/entry#A0A8V0ZTB3-1", "sequence": { "sequence": "MSKKQNPKDPSGFIFDVQSNTVMAQGGTFENMKEKINAVRAIVPNRSNNEIVLVLQHFDNCVDKTVQAFMEGNASEVLKEWTVTGKKKNKKKKTKPKPQAEASPGPADPRKLVSTGEEQSANSEKGGINGFHVNGCAHDTESVDSLSEGLDALSIDARELEDCEPAVPDMPERTVPQLENGIADLDTKSLTVHPAQSPSSLRQRPDQHSASRSGSRPTASTSLPAVRLENVPFSPANKKLGSNIEKSVKDLQRCTVSLARYRVVVKEEMDASIKKMKQVFAELQSSLMDREVALLAEMDKVKAEAMEILMSRQKKAEALKKMTDVAVRMSEEQLIELRADIKHFVSERKYDEELGRVARFTCDLDALKKSIAAFGQVSHPKNSYSTRSRCSSVTAVSPSSPSNASAPSSPACASAISLTTVSKKPPSSVEAAVEGAGSHPPQPHREAAPGNRRPGPPGPPGSRPQSHTAPPPARRPGGPRHRSGAGPALGRHQSSPGSPHQMQPPEPGPAAGAAATHSKGLPQRKPRASRQEGASS", "length": 536, "header": "tr|A0A8V0ZTB3-1|A0A8V0ZTB3_CHICK Isoform 1 of Spermatosis associated serine rich 2 OS=Gallus gallus OX=9031 GN=SPATS2 PE=1 SV=1 CANONICAL=A0A8V0ZTB3-1" }, "locus": { "chromosome": "34", "start_pos": 1856111, "end_pos": 1839318, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056273.1", "url": "https://www.ensembl.org/id/ENSGALT00010056273.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034064.1", "url": "https://www.ensembl.org/id/ENSGALP00010034064.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:426663", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:426663", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A5G2R8I7-1", "protein_name": "Spermatosis associated serine rich 2", "gene_name": "SPATS2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSRKQNQKDSSGFIFDLQSNTVLAQGGTFENMKEKINAVRAIVPNKSNNEIILVLQHFDNCVDKTVQAFMEGSASEVLKEWTVTGKKKNKKKKSKPKPAAQPSNSIPDSNKSVPTQEEQSAPSSEKGGINGYHVNGAINDTESVDSLSEGMETLSVDARELEDPESATPDVLTRTGSMLENGVSDFESKSLTMHSTQNSQQNRNAAKSLSRSTLGPPFSNLGLEDVPLSSTNKKLGSNIEKSVKDLQRCTVSLARYRVVVKEEMDASIKKMKQAFAELQSCLMDREVALLAEMDKVKAEAMEILLSRQKKAELLKKMTDVAVRMSEEQLVELRADIKHFVSERKYDEDLGRVARFTCDVETLKKNIDSFGQVSHPKNSYSTRSRCSSVASVSLSNPCDASAASSSTCASAPSLTSANKKSSAPGETPAATADSSGRPYQPHREVLPGNRRGGQGYRPQGPKSSDPTNQGRHDSAGRYRNSSWYSSGSRYQSVPSQAPGNISERGQAHPAGTNGTGASTEPGPPKPSFKKGLPQRKPRTSQPETVNS", "length": 546 }, "evidence": [ { "id": "A0A8V0ZTB3", "url": "https://omabrowser.org/oma/group/A0A8V0ZTB3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1LX68-1", "protein_name": "Spermatogenesis associated, serine-rich 2", "gene_name": "Spats2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSRKQSQKDSSGFIFDLQSNTVLAQGGTFENMKEKINAVRAIVPNKSNNEIILVLQHFDNCVDKTVQAFMEGSASEVLKEWIVTGKKKNKKKKSKPKPASEASGSAPDSSKSAPAEEGQPASSEKGSINGYHVNGAINDTESVDSLSEGLETLSIDARELEDPEFATADALDRAGSVLENGVSDFEPKSLTTHSISNVQQSRNAAKSLSRATTGAQVSNLGMENVPLSSTNKKLGSNIEKSVKDLQRCTVSLARYRVVVKEEMDASIKKMKQAFAELQSCLMDREVALLAEMDKVKAEAMEILLSRQKKAELLKKMTDVAVRMSEEQLVELRADIKHFVSERKYDEDLGRVARFTCDVETLKQSIDSFGQVSHPKNSYSTRSRCSSLLPVSLLPVSCSGPSDVSAASSAPDASAPSLPGANKRNSAPREASAAMTNSSDRPCQAHREVFSGNRRGGQGYRPQNQKTTDPPNQGRHDNAGRYRNSSWYSSGPRHQAVPPQAPGSAGEWSRPYSAGTNGTGASSEPSPPKPSFKKGLPQRKPRASQAEAANS", "length": 550 }, "evidence": [ { "id": "A0A8V0ZTB3", "url": "https://omabrowser.org/oma/group/A0A8V0ZTB3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1MK70-1", "protein_name": "Spermatosis associated serine rich 2", "gene_name": "SPATS2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSRKQNQKDSSGFIFDLQSKTVLAQGGAFENMKEKINAVRAVVPNKSNNEIILVLQHFDNCVDKTVQAFMEGSASEVLKEWTVTGKKKNKKKKSKPKPAAEPSNSIPDSNKSVSIQEEQSAPSSEKGGVNGYHVNGAINDTESVDSLSEGMETLSIEARELEDPESAPSEMLDRTGSMLENGVSDFESRSLTMHSTQNSQQNKNAAKSLSRTTVGPQLSSLGMEDVPLSSTNKKLGSNIEKSVKDLQRCTVSLARYRVVVKEEMDASIKKMKQAFAELQSCLMDREVALLAEMDKVKAEAMEILLSRQKKAELLKKMTDVAVRMSEEQLVELRADIKHFVSERKYDEDLGRVARFTCDVETLKKNIDSFGQVSHPKNSYSTRSRCSLVASVSLSNPCDASAAAASTCASAPSLTSANKKNSAPGETPATTANSGGRSYQPHREALPGNRRGGQGYRPQGPKSSDPTNQGRHDSVGRYRNSSWYSSGSRYQSAPPQAPGNTSERGQAHSAGTNGTGASMEPGPPKPSFRKGLPQRKPRTSQPDVVNS", "length": 546 }, "evidence": [ { "id": "A0A8V0ZTB3", "url": "https://omabrowser.org/oma/group/A0A8V0ZTB3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8K1N4-1", "protein_name": "Spermatogenesis-associated serine-rich protein 2", "gene_name": "Spats2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSRKQSQKDSSGFIFDLQSNTVLAQGGTFENMKEKINAVRAIVPNKSNNEIILVLQHFDNCVDKTVQAFMEGSASEVLKEWIVTGKKKNKKKKSKPKPASEASGSAPDSSKSAPIQEEQPASSEKGSINGYHVNGAINDAESVDSLSEGLETLSIDARELEDPEFAAAETLDRTGSVLENGVSDFEPKSLTAHSISNVQQSRNAAKSLSRTTPGAQVSNLGMENVPLSSTNKKLGSNIEKSVKDLQRCTVSLARYRVVVKEEMDASIKKMKQAFAELQSCLMDREVALLAEMDKVKAEAMEILLSRQKKAELLKKMTDVAVRMSEEQLVELRADIKHFVSERKYDEDLGRVARFTCDVETLKQSIDSFGQVSHPKNSYSTRSRCSLVAPVSLSGPSDGSAASSSPDASVPSLPGANKRNCAPREASAAMTNSSDRPCQAHREVFPGNRRGGQGYRAQSQKTADPSNPGRHDSVGRYRNSSWYSSGPRYQGVPPQAPGNAGERSRPYSAGTNGTGAISEPSPPKPSFKKGLPQRKPRASQAEAANS", "length": 545 }, "evidence": [ { "id": "A0A8V0ZTB3", "url": "https://omabrowser.org/oma/group/A0A8V0ZTB3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTB3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTB3" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTB3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTB3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 403, "end_pos": 405, "annotation": "n_glycosylation_sequon" }, { "start_pos": 45, "end_pos": 47, "annotation": "n_glycosylation_sequon" }, { "start_pos": 73, "end_pos": 75, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 403, "end_pos": 405 }, { "start_pos": 45, "end_pos": 47 }, { "start_pos": 73, "end_pos": 75 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZTK4-1", "uniprot_ac": "A0A8V0ZTK4", "uniprot_id": "A0A8V0ZTK4_CHICK", "mass": { "chemical_mass": 311283.0, "monoisotopic_mass": 311283.0 }, "refseq": {}, "gene_names": [ { "name": "MUC5ACL", "type": "recommended", "evidence": [ { "id": "A0A8V0ZTK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTK4" } ] } ], "protein_names": [ { "name": "VWFD domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8V0ZTK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTK4/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Ovomucin, the glycoprotein responsible for the gel properties of egg white, is composed for 2 subunits, alpha-ovomucin/MUC5B and beta-ovomucin/MUC6.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTB5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTB5#function" }, { "database": "UniProtKB", "id": "ARBA00054401", "url": "https://www.uniprot.org/uniprotkb/ARBA00054401#function" }, { "database": "UniProtKB", "id": "A0A8V0ZNE4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNE4#function" }, { "database": "UniProtKB", "id": "A0A8V0ZWW5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWW5#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTK4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTK4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MUC5ACL", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTK4", "locus": {} } ], "crossref": [ { "id": "cd19941", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19941", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001007", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001007", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001846", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001846", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002919", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002919", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014853", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014853", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025155", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025155", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036084", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036084", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050780", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050780", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058753", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058753", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZNE4", "url": "https://www.orthodb.org/?gene=A0A8V0ZNE4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZTB5", "url": "https://www.orthodb.org/?gene=A0A8V0ZTB5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZTK4", "url": "https://www.orthodb.org/?gene=A0A8V0ZTK4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZVI7", "url": "https://www.orthodb.org/?gene=A0A8V0ZVI7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZWW5", "url": "https://www.orthodb.org/?gene=A0A8V0ZWW5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A122", "url": "https://www.orthodb.org/?gene=A0A8V1A122", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11339", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11339", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11339:SF408", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11339:SF408", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00094", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00094", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01826", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01826", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08742", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08742", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13330", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13330", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25962", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25962", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZNE4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNE4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZNE4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNE4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZTB5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTB5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZTB5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTB5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZTK4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTK4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZTK4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTK4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZVI7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVI7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZVI7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVI7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZWW5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWW5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZWW5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWW5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A122", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A122", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A122-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A122-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEGIYSKLQNILMAHFESAAGNPSHNGRVCSTWGNFHFKNFDGDIFYFPGVCNYIFASNCKSPYEDFNIQIRRTMVENATVITHVIMRLEGAVVELTRTSVLVNGKQIQMPYSHMGVLIERSNSYIKVSAKLGLTFLWNEEDALLVELDKKYANQTCGLCGDFNGIPTNNEFISQNAKLTAVQFGNRQKIDGPTEQCDDPIPSAVLMNCSSEFASICKTVLTSEAFTSCNALVDVQDYIDTCIQDLCHCDTSMADFCMCNTFAEYSRQCAHAGGQPLNWRTSELCPKSCPFNMQHQECGSPCSDTCSNPERSALCEDHCTDGCTCPPGMVFDDINGAGCIPRKECHCTYEGETYAPGTSFSSKCRSCTCAGGEWTCVTQSCPATCSIEGGSHITTYDEKYYSFYGDCSYVLTKLCDSNDFTVLGDIHKCGLTDTETCLKGVAISLSGGQTNIVIQPSGSVFVNMIYTQLPFSAANVTIFRPSSFFIILQTTFGLQLQIQIVPLMQLFINLDPSQKGQTCGLCGNFNDIQTDDFKTTSGVIEGTSAAFGNTWKTRADCPDAKITFENPCTLSIENDKYAQHWCGLLSDTTGPFAECHSTVNPEVYQKNCMFDTCNCENTEDCMCAALSSYVRACAAKGILLNGWRNKVCTKYTNTCPKSLEYTYNVDSCQPTCRSLSEPDVTCNIKFVPVDGCTCVNGTYMDESGKCVPAASCPCYYKGMPLSTGEVIHDNGVVCTCSYGKLSCIGEKPPPVCAPPMVYVDCGNATAGVTGAECQKSCQTLDMECYKTHCVSGCICPPNYVSDGKGGCIAAEECPCVHNGDSYRPGESIRVGCNNCTCRNRKWHCSEEPCLETCSVYGDGHYTTFDGKRFDFEGDCEYVLIQNYCGRKGLNQGTFRVITENIPCGTTGTTCSKSIKVFLGNYELVLSDGHSDVIQRSPGGEMPFQIRSMGIYMVVDTTVGLILMWDKKTSIFIKLSPSFQGHVCGLCGNYDGNGNNDFTTRSQSVVGNVLEFANSWKVSSTCPNANQTKDPCTANPYRKSWAQKQCSIITSEVFAKCHSQVEPNEYYQACVDDACACDTGGDCECFCTAVAAYAQACNELDICISWRTPSICPLFCDYYNPQGECEWHYKPCGAPCMKTCNNPSGKCLHELRGLEGCYPHCPKNKPYFDEETMACVSNCGCYENGKHYKPGMQMPSKQNCQTCECTNHGKICKYDEHECVCIYEGRTYNYTDMIYNTTDGIGGCIVATCGPNGTLQRVVYDCPISTSPTTPFHFSTTPPATASTGIIFYNCTESNVKKKYSFFSFRTDKVFKLFSFILSVTSSPTTSVCVHEVCQWSEWYDGSPLIPGFDGGDFETFSDLRAKGYEVCRDPKAVQCRAEKFPNIPLKDLGQRVECNTQSGLICYNKDQISTMCYNYEIRILCCVFVPCSSTSSITTPYETSTLITHTPVPEKTTTATTSTSPEAIRTTPCQPKCKWSKWYDVHFPTLHNKGDYETYQDIRSAGKAICRNPEKIQCRAEKYPHKSIEEIGQVVHCNVTYGLICRNEDQKGELHICLNYQVKVFCCDDYSHCQTRVTPTVPEEITTTITQSPATTTSETSTFTTKLTSPVTISPTTSALCVKEECDWSVWYDVSYPEPGYNDGDFDTVQNIRKQGYEVCANRMAVECRAVRFPNTPYQLLEQHITCNTKEGLICYNKDQLPPICYNYEVRFKCCKNVTVPCQTTKTPYSTTKKPTTSTISTTQTTPYTETSTMTYTPKIQTKHKTTTIETIPPRTENIHSETTSTPKQSIQTETKTTTILTVTTSTSTATPTTTIETSTSTSTLTPTPTLISTTSSPSTTTHVTACELELCSWTDWFDVDFPSSGTSQGDFETYQHIRAAGKEVCQQPKQIECQAEDYPEISIEQVGQVVQCDVHYGLVCKNQDQHGSFKMCLNYRIRVLCCRPNPDCVQTITPTTSPTTTISTGTSSSTTPTLSVTTSTSTATPTTTIETSTSTSTLTPTPTLISTTSSPSTTTHVTACELELCSWTDWFDVDFPSSGTSQGDFETYQHIRAAGKEVCQQPKQIECQAEDYPEISIEQVGQVVQCDVHYGLVCKNQDQHGSFKMCLNYRIRVLCCRPNPDCVQTITPTTSPTTTISTGTSSSTTPTLSVTTSTSTATPTTTIETSTSTSTLTPTPTLISTTSSPSTTTHVTACELELCSWTDWFDVDFPSSGTSQGDFETYQHIRAAGKEVCQQPKQIECQAEDYPEISIEQVGQVVQCDVHYGLVCKNQDQHGSFKMCLNYRIRVLCCRPNPDCVQTITPTTSPTTTISTGTSSSTTPTLSVTTSTSTATPTTTIETSTSTSTLTPTPTLISTTSSPSTTTHVTACELELCSWTDWFDVDFPSSGTSQGDFETYQHIRAAGKEVCQQPKQIECQAEDYPEISIEQVGQVVQCDVHYGLVCKNQDQHGSFKMCLNYRIRVLCCRPNPDCVQTITPTTSPTTTISTGTSSSTTPTLSVTTSTSTATPTTTIETSTSTSTLTPTPTLISTTSSPSTTTHVTACELELCSWTDWFDVDFPSSGTSQGDFETYQHIRAAGKEVCQQPKQIECQAEDYPEISIEQVGQVVQCDVHYGLVCKNQDQHGSFKMCLNYRIRVLCCRPNPDCVQTITPTTSPTTTISTGTSSSTTPTLSKPAPAPAPSRPPLPSSPLPAHLPPRPTLPPANLNSAPGPTGLTLTSPPRGQARETLKPTSTSALPGRKSVNSQNKLSARPRTTPRFPSNKSDRWCSVTFTMDWCARTRTSMAVLRCASTTGSASSAAGLTPTACRPLLLPPVPPPPSPQAPPPPLHPPSQSQPPPPPLRPLQQ", "length": 2841, "header": "tr|A0A8V0ZTK4-1|A0A8V0ZTK4_CHICK Isoform 1 of VWFD domain-containing protein OS=Gallus gallus OX=9031 GN=MUC5ACL PE=1 SV=1 CANONICAL=A0A8V0ZTK4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZNE4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTK4/entry#A0A8V0ZNE4-1", "sequence": { "sequence": "MGTGSGTQIPLWISILALAYIQIKVQAQGNEQQSQSNYDSPSFLQRQNNFPPASKSHGVTIIPPLQNTLKVKAGNPSHNGRVCSTWGNFHFKNFDGDIFYFPGVCNYIFASNCKSPYEDFNIQIRRTMVENATVITHVIMRLEGAVVELTRTSVLVNGKQIQMPYSHMGVLIERSNSYIKVSAKLGLTFLWNEEDALLVELDKKYANQTCGLCGDFNGIPTNNEFISQNAKLTAVQFGNRQKIDGPTEQCDDPIPSAVLMNCSSEFASICKTVLTSEAFTSCNALVDVQDYIDTCIQDLCHCDTSMADFCMCNTFAEYSRQCAHAGGQPLNWRTSELCPKSCPFNMQHQECGSPCSDTCSNPERSALCEDHCTDGCTCPPGMVFDDINGAGCIPRKECHCTYEGETYAPGTSFSSKCRSCTCAGGEWTCVTQSCPATCSIEGGSHITTYDEKYYSFYGDCSYVLTKLCDSNDFTVLGDIHKCGLTDTETCLKGVAISLSGGQTNIVIQPSGSVFVNMIYTQLPFSAANVTIFRPSSFFIILQTTFGLQLQIQIVPLMQLFINLDPSQKGQTCGLCGNFNDIQTDDFKTTSGVIEGTSAAFGNTWKTRADCPDAKITFENPCTLSIENDKYAQHWCGLLSDTTGPFAECHSTVNPEVYQKNCMFDTCNCENTEDCMCAALSSYVRACAAKGILLNGWRNKVCTKYTNTCPKSLEYTYNVDSCQPTCRSLSEPDVTCNIKFVPVDGCTCVNGTYMDESGKCVPAASCPCYYKGMPLSTGEVIHDNGVVCTCSYGKLSCIGEKPPPVCAPPMVYVDCGNATAGVTGAECQKSCQTLDMECYKTHCVSGCICPPNYVSDGKGGCIAAEECPCVHNGDSYRPGESIRVGCNNCTCRNRKWHCSEEPCLETCSVYGDGHYTTFDGKRFDFEGDCEYVLIQNYCGRKGLNQGTFRVITENIPCGTTGTTCSKSIKVFLGNYELVLSDGHSDVIQRSPGGEMPFQIRSMGIYMVVDTTVGLILMWDKKTSIFIKLSPSFQGHVCGLCGNYDGNGNNDFTTRSQSVVGNVLEFANSWKVSSTCPNANQTKDPCTANPYRKSWAQKQCSIITSEVFAKCHSQVEPNEYYQACVDDACACDTGGDCECFCTAVAAYAQACNELDICISWRTPSICPLFCDYYNPQGECEWHYKPCGAPCMKTCNNPSGKCLHELRGLEGCYPHCPKNKPYFDEETMACVSNCGCYENGKHYKPGMQMPSKQNCQTCECTNHGKICKYDEHECVCIYEGRTYNYTDMIYNTTDGIGGCIVATCGPNGTLQRVVYDCPISTSPTTPFHFSTTPPATASTDTKPSNCTESNVKKKYITSSPTTSVCVHEVCQWSEWYDGSPLIPGFDGGDFETFSDLRAKGYEVCRDPKAVQCRAEKFPNIPLKDLGQRVECNTQSGLICYNKDQISTMCYNYEIRILCCVFVPCSSTSSITTPYETSTLITHTPVPEKTTTATSTIITTSSTTTETGSTTITSTSSETASTSPEAIRTTPCQPKCKWSKWYDVHFPTLHNKGDYETYQDIRSAGKAICRNPEKIQCRAEKYPHKSIEEIGQVVHCNVTYGLICRNEDQKGELHICLNYQVKVFCCDDYSHCQTRVTPTVPEEITTTITQSPATTTSETSTFTTKLTSPVTISPTTSALCVKEECDWSVWYDVSYPEPGYNDGDFDTVQNIRKQGYEVCANRMAVECRAVRFPNTPYQLLEQHITCNTKEGLICYNKDQLPPICYNYEVRFKCCKNVTVPCQTTKTPYSTTKKPTTSTISTTQTTPYTETSTMTYTPKIQTKHKTTTIETIPPRTENIHSETTSTPKQSIQTETKTTTILTVTTSTSTATPTTTIETSTSTSTLTPTPTLISTTSSPSTTTHVTACELELCSWTDWFDVDFPSSGTSQGDFETYQHIRAAGKEVCQQPKQIECQAEDYPEISIEQVGQVVQCDVHYGLVCKNQDQHGSFKMCLNYRIRVLCCRPTTTISTETSTSTSTLTPTPTLISTTSSPSTTTHVTACELELCSWTDWFDVDFPSSGTSQGDFETYQHIRAAGKEVCQQPKQIECQAEDYPEISIEQVGQVVQCDVHYGLVCKNQDQHGSFKMCLNYRIRVLCCRPNPDC", "length": 2139, "header": "tr|A0A8V0ZNE4-1|A0A8V0ZNE4_CHICK Computationally mapped isoform of VWFD domain-containing protein OS=Gallus gallus OX=9031 GN=MUC5ACL PE=1 SV=1 CANONICAL=A0A8V0ZTK4-1" }, "locus": { "chromosome": "5", "start_pos": 14412013, "end_pos": 14385431, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010057468.1", "url": "https://www.ensembl.org/id/ENSGALT00010057468.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034924.1", "url": "https://www.ensembl.org/id/ENSGALP00010034924.1" } ] } }, { "isoform_ac": "A0A8V0ZTB5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTK4/entry#A0A8V0ZTB5-1", "sequence": { "sequence": "MEGIYSKLQNILMAHFESAAGNPSHNGRVCSTWGNFHFKNFDGDIFYFPGVCNYIFASNCKSPYEDFNIQIRRTMVENATVITHVIMRLEGAVMPYSHMGVLIERSNSYIKVSAKLGLTFLWNEEDALLVELDKKYANQTCGLCGDFNGIPTNNEFISQNAKLTAVQFGNRQKIDGPTEQCDDPIPSAVLMNCSSEFASICKTVLTSEAFTSCNALVDVQDYIDTCIQDLCHCDTSMADFCMCNTFAEYSRQCAHAGGQPLNWRTSELCPKSCPFNMQHQECGSPCSDTCSNPERSALCEDHCTDGCTCPPGMVFDDINGAGCIPRKECHCTYEGETYAPGTSFSSKCRSCTCAGGEWTCVTQSCPATCSIEGGSHITTYDEKYYSFYGDCSYVLTKLCDSNDFTVLGDIHKCGLTDTETCLKGVAISLSGGQTVIVSTVYLKLNYFSLSTANVTIFRPSSFFIILQTTFGLQLQIQIVPLMQLFINLDPSQKGQTCGLCGNFNDIQTDDFKTTSGVIEGTSAAFGNTWKTRADCPDAKITFENPCTLSIENDKYAQHWCGLLSDTTGPFAECHSTVNPEVYQKNCMFDTCNCENTEDCMCAALSSYVRACAAKGILLNGWRNKVCTKYTNTCPKSLEYTYNVDSCQPTCRSLSEPDVTCNIKFVPVDGCTCVNGTYMDESGKCVPAASCPCYYKGMPLSTGEVIHDNGVIQIHGSFHTSCAFCSLPVCAPPMVYVDCGNATAGVTGAECQKSCQTLDMECYKTHCVSGCICPPNYVSDGKGGCIAAEECPCVHNGDSYRPGESIRVGCNNCTCRNRKWHCSEEPCLETCSVYGDGHYTTFDGKRFDFEGDCEYVLIQNYCGRKGLNQGTFRVITENIPCGTTGTTCSKSIKVFLGNYELVLSDGHSDVIQRSPGGEMPFQIRSMGIYMVVDTTVGLILMWDKKTSIFIKLSPSFQGHVCGLCGNYDGNGNNDFTTRSQSVVGNVLEFANSWKVSSTCPNANQTKDPCTANPYRKSWAQKQCSIITSEVFAKCHSQVEPNEYYQACVDDACACDTGGDCECFCTAVAAYAQACNELDICISWRTPSICPLFCDYYNPQGECEWHYKPCGAPCMKTCNNPSGKCLHELRGLEGCYPHCPKNKPYFDEETMACVSNCGCYENGKHYKPGITILFCFTECVCIYEGRTYNYTDMIYNTTDGIGGCIVATCGPNGTLQRVVYDCPISTSPTTPFHFSTTPPATASTVTSSPTTSVCVHEVCQWSEWYDGSPLIPGFDGGDFETFTICRNPEKIQCRAEKYPHKSIEEIGQVVHCNVTYGLICRNEDQKGELHICLNYQVKVFCCDDYSHCQTRVTPTVPEEITTTITQSPATTTSETSTFTTKLTSPVTISPTTSCCKNVTVPCQTTKTPYSTTKKPTTSTISTTQTTPYTETSTMTYTPKIQTKHKTTTIETIPPRTENIHSETTSTPKQSIQTETKTTTILTVTTSTSTATPTTTIETSTSTSTLTPTPTLISTTSSPSTTTHVTACELELCSWTDWFDVDFPSSGTSQGDFETYQ", "length": 1554, "header": "tr|A0A8V0ZTB5-1|A0A8V0ZTK4_CHICK Computationally mapped isoform of VWFD domain-containing protein OS=Gallus gallus OX=9031 GN=MUC5ACL PE=1 SV=1 CANONICAL=A0A8V0ZTK4-1" }, "locus": { "chromosome": "5", "start_pos": 14407924, "end_pos": 14386172, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010057250.1", "url": "https://www.ensembl.org/id/ENSGALT00010057250.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034814.1", "url": "https://www.ensembl.org/id/ENSGALP00010034814.1" } ] } }, { "isoform_ac": "A0A8V0ZTK4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTK4/entry#A0A8V0ZTK4-1", "sequence": { "sequence": "MEGIYSKLQNILMAHFESAAGNPSHNGRVCSTWGNFHFKNFDGDIFYFPGVCNYIFASNCKSPYEDFNIQIRRTMVENATVITHVIMRLEGAVVELTRTSVLVNGKQIQMPYSHMGVLIERSNSYIKVSAKLGLTFLWNEEDALLVELDKKYANQTCGLCGDFNGIPTNNEFISQNAKLTAVQFGNRQKIDGPTEQCDDPIPSAVLMNCSSEFASICKTVLTSEAFTSCNALVDVQDYIDTCIQDLCHCDTSMADFCMCNTFAEYSRQCAHAGGQPLNWRTSELCPKSCPFNMQHQECGSPCSDTCSNPERSALCEDHCTDGCTCPPGMVFDDINGAGCIPRKECHCTYEGETYAPGTSFSSKCRSCTCAGGEWTCVTQSCPATCSIEGGSHITTYDEKYYSFYGDCSYVLTKLCDSNDFTVLGDIHKCGLTDTETCLKGVAISLSGGQTNIVIQPSGSVFVNMIYTQLPFSAANVTIFRPSSFFIILQTTFGLQLQIQIVPLMQLFINLDPSQKGQTCGLCGNFNDIQTDDFKTTSGVIEGTSAAFGNTWKTRADCPDAKITFENPCTLSIENDKYAQHWCGLLSDTTGPFAECHSTVNPEVYQKNCMFDTCNCENTEDCMCAALSSYVRACAAKGILLNGWRNKVCTKYTNTCPKSLEYTYNVDSCQPTCRSLSEPDVTCNIKFVPVDGCTCVNGTYMDESGKCVPAASCPCYYKGMPLSTGEVIHDNGVVCTCSYGKLSCIGEKPPPVCAPPMVYVDCGNATAGVTGAECQKSCQTLDMECYKTHCVSGCICPPNYVSDGKGGCIAAEECPCVHNGDSYRPGESIRVGCNNCTCRNRKWHCSEEPCLETCSVYGDGHYTTFDGKRFDFEGDCEYVLIQNYCGRKGLNQGTFRVITENIPCGTTGTTCSKSIKVFLGNYELVLSDGHSDVIQRSPGGEMPFQIRSMGIYMVVDTTVGLILMWDKKTSIFIKLSPSFQGHVCGLCGNYDGNGNNDFTTRSQSVVGNVLEFANSWKVSSTCPNANQTKDPCTANPYRKSWAQKQCSIITSEVFAKCHSQVEPNEYYQACVDDACACDTGGDCECFCTAVAAYAQACNELDICISWRTPSICPLFCDYYNPQGECEWHYKPCGAPCMKTCNNPSGKCLHELRGLEGCYPHCPKNKPYFDEETMACVSNCGCYENGKHYKPGMQMPSKQNCQTCECTNHGKICKYDEHECVCIYEGRTYNYTDMIYNTTDGIGGCIVATCGPNGTLQRVVYDCPISTSPTTPFHFSTTPPATASTGIIFYNCTESNVKKKYSFFSFRTDKVFKLFSFILSVTSSPTTSVCVHEVCQWSEWYDGSPLIPGFDGGDFETFSDLRAKGYEVCRDPKAVQCRAEKFPNIPLKDLGQRVECNTQSGLICYNKDQISTMCYNYEIRILCCVFVPCSSTSSITTPYETSTLITHTPVPEKTTTATTSTSPEAIRTTPCQPKCKWSKWYDVHFPTLHNKGDYETYQDIRSAGKAICRNPEKIQCRAEKYPHKSIEEIGQVVHCNVTYGLICRNEDQKGELHICLNYQVKVFCCDDYSHCQTRVTPTVPEEITTTITQSPATTTSETSTFTTKLTSPVTISPTTSALCVKEECDWSVWYDVSYPEPGYNDGDFDTVQNIRKQGYEVCANRMAVECRAVRFPNTPYQLLEQHITCNTKEGLICYNKDQLPPICYNYEVRFKCCKNVTVPCQTTKTPYSTTKKPTTSTISTTQTTPYTETSTMTYTPKIQTKHKTTTIETIPPRTENIHSETTSTPKQSIQTETKTTTILTVTTSTSTATPTTTIETSTSTSTLTPTPTLISTTSSPSTTTHVTACELELCSWTDWFDVDFPSSGTSQGDFETYQHIRAAGKEVCQQPKQIECQAEDYPEISIEQVGQVVQCDVHYGLVCKNQDQHGSFKMCLNYRIRVLCCRPNPDCVQTITPTTSPTTTISTGTSSSTTPTLSVTTSTSTATPTTTIETSTSTSTLTPTPTLISTTSSPSTTTHVTACELELCSWTDWFDVDFPSSGTSQGDFETYQHIRAAGKEVCQQPKQIECQAEDYPEISIEQVGQVVQCDVHYGLVCKNQDQHGSFKMCLNYRIRVLCCRPNPDCVQTITPTTSPTTTISTGTSSSTTPTLSVTTSTSTATPTTTIETSTSTSTLTPTPTLISTTSSPSTTTHVTACELELCSWTDWFDVDFPSSGTSQGDFETYQHIRAAGKEVCQQPKQIECQAEDYPEISIEQVGQVVQCDVHYGLVCKNQDQHGSFKMCLNYRIRVLCCRPNPDCVQTITPTTSPTTTISTGTSSSTTPTLSVTTSTSTATPTTTIETSTSTSTLTPTPTLISTTSSPSTTTHVTACELELCSWTDWFDVDFPSSGTSQGDFETYQHIRAAGKEVCQQPKQIECQAEDYPEISIEQVGQVVQCDVHYGLVCKNQDQHGSFKMCLNYRIRVLCCRPNPDCVQTITPTTSPTTTISTGTSSSTTPTLSVTTSTSTATPTTTIETSTSTSTLTPTPTLISTTSSPSTTTHVTACELELCSWTDWFDVDFPSSGTSQGDFETYQHIRAAGKEVCQQPKQIECQAEDYPEISIEQVGQVVQCDVHYGLVCKNQDQHGSFKMCLNYRIRVLCCRPNPDCVQTITPTTSPTTTISTGTSSSTTPTLSKPAPAPAPSRPPLPSSPLPAHLPPRPTLPPANLNSAPGPTGLTLTSPPRGQARETLKPTSTSALPGRKSVNSQNKLSARPRTTPRFPSNKSDRWCSVTFTMDWCARTRTSMAVLRCASTTGSASSAAGLTPTACRPLLLPPVPPPPSPQAPPPPLHPPSQSQPPPPPLRPLQQ", "length": 2841, "header": "tr|A0A8V0ZTK4-1|A0A8V0ZTK4_CHICK Isoform 1 of VWFD domain-containing protein OS=Gallus gallus OX=9031 GN=MUC5ACL PE=1 SV=1 CANONICAL=A0A8V0ZTK4-1" }, "locus": { "chromosome": "5", "start_pos": 14407924, "end_pos": 14383222, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010057439.1", "url": "https://www.ensembl.org/id/ENSGALT00010057439.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034906.1", "url": "https://www.ensembl.org/id/ENSGALP00010034906.1" } ] } }, { "isoform_ac": "A0A8V0ZVI7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTK4/entry#A0A8V0ZVI7-1", "sequence": { "sequence": "MEGIYSKLQNILMAHFESAAGNPSHNGRVCSTWGNFHFKNFDGDIFYFPGVCNYIFASNCKSPYEDFNIQIRRTMVENATVITHVIMRLEGAVVELTRTSVLVNGKQYMPYSHMGVLIERSNSYIKVSAKLGLTFLWNEEDALLVELDKKYANQTCGLCGDFNGIPTNNEFISQNAKLTAVQFGNRQKIDGPTEQCDDPIPSAVLMNCSSEFASICKTVLTSEAFTSCNALVDVQDYIDTCIQDLCHCDTSMADFCMCNTFAEYSRQCAHAGGQPLNWRTSELCPKSCPFNMQHQECGSPCSDTCSNPERSALCEDHCTDGCTCPPGMVFDDINGAGCIPRKECHCTYEGETYAPGTSFSSKCRSCTCAGGEWTCVTQSCPATCSIEGGSHITTYDEKYYSFYGDCSYVLTKLCDSNDFTVLGDIHKCGLTDTETCLKGVAISLSGGQTVIVSTVYLKLNYFSLSTANVTIFRPSSFFIILQTTFGLQLQIQIVPLMQLFINLDPSQKGQTCGLCGNFNDIQTDDFKTTSGVIEGTSAAFGNTWKTRADCPDAKITFENPCTLSIENDKYAQHWCGLLSDTTGPFAECHSTVNPEVYQKNCMFDTCNCENTEDCMCAALSSYVRACAAKGILLNGWRNKVCTKYTNTCPKSLEYTYNVDSCQPTCRSLSEPDVTCNIKFVPVDGCTCVNGTYMDESGKCVPAASCPCYYKGMPLSTGEVIHDNGVVCTCSYGKLSCIGEKPPPVCAPPMVYVDCGNATAGVTGAECQKSCQTLDMECYKTHCVSGCICPPNYVSDGKGGCIAAEECPCVHNGDSYRPGESIRVGCNNCTCRNRKWHCSEEPCLETCSVYGDGHYTTFDGKRFDFEGDCEYVLIQNYCGRKGLNQGTFRVITENIPCGTTGTTCSKSIKVFLGNYELVLSDGHSDVIQRSPGGEMPFQIRSMGIYMVVDTTVGLILMWDKKTSIFIKLSPSFQGHVCGLCGNYDGNGNNDFTTRSQSVVGNVLEFANSWKVSSTCPNANQTKDPCTANPYRKSWAQKQCSIITSEVFAKCHSQVEPNEYYQACVDDACACDTGGDCECFCTAVAAYAQACNELDICISWRTPSICPLFCDYYNPQGECEWHYKPCGAPCMKTCNNPSGKCLHELRGLEGCYPHCPKNKPYFDEETMACVSNCGCYENGKHYKPGMQMPSKQNCQTCECTNHGKICKYDEHECVCIYEGRTYNYTDMIYNTTDGIGGCIVATCGPNGTLQRVVYDCPISTSPTTPFHFSTTPPATASTGIIFYNCTESNVKKKYSFFSFRTDKVCLSPISALSKEKTIFSLNFKLFSFILSVTSSPTTSVCVHEVCQWSEWYDGSPLIPGFDGGDFETFSDLRAKGYEVCRDPKAVQCRAEKFPNIPLKDLGQRVECNTQSGLICYNKDQISTMCYNYEIRILCCVFVPCSSTSSITTPYETSTLITHTPVPEKTTTATSTIITTSSTTTETGSTTITSTSSETASTSPEAIRTTPCQPKCKWSKWYDVHFPTLHNKGDYETYQDIRSAGKAICRNPEKIQCRAEKYPHKSIEEIGQVVHCNVTYGLICRNEDQKGELHICLNYQVKVFCCDDYSHCQTRVTPTVPEEITTTITQSPATTTSETSTFTTKLTSPVTISPTTSALCVKEECDWSVWYDVSYPEPGYNDGDFDTVQNIRKQGYEVCANRMAVECRAVRFPNTPYQLLEQHITCNTKEGLICYNKDQLPPICYNYEVRFKCCKNVTVPCQTTKTPYSTTKKPTTSTISTTQTTPYTETSTMTYTPKIQTKHKTTTIETIPPRTENIHSETTSTPKQSIQTETKTTTILTVTTSTSTATPTTTIETSTSTSTLTPTPTLISTTSSPSTTTHVTACELELCSWTDWFDVDFPSSGTSQGDFETYQHIRAAGKEVCQQPKQIECQAEDYPEISIEQVGQVVQCDVHYGLVCKNQDQHGSFKMCLNYRIRVLCCRPNPDCVQTITPTTSPTTTISTGTSSSTTPTLSVTTSTSTATPTTTIETSTSTSTLTPTPTLISTTSSPSTTTHVTACELELCSWTDWFDVDFPSSGTSQGDFETYQHIRAAGKEVCQQPKQIECQAEDYPEISIEQVGQVVQCDVHYGLVCKNQDQHGSFKMCLNYRIRVLCCRPNPDCVQTITPTTSPTTTISTGTSSSTTPTLSVTTSTSTATPTTTIETSTSTSTLTPTPTLISTTSSPSTTTHVTACELELCSWTDWFDVDFPSSGTSQGDFETYQHIRAAGKEVCQQPKQIECQAEDYPEISIEQVGQVVQCDVHYGLVCKNQDQHGSFKMCLNYRIRVLCCRPNPDCVQTITPTTSPTTTISTGTSSSTTPTLSVTTSTSTATPTTTIETSTSTSTLTPTPTLISTTSSPSTTTHVTACELELCSWTDWFDVDFPSSGTSQGDFETYQHIRAAGKEVCQQPKQIECQAEDYPEISIEQVGQVVQCDVHYGLVCKNQDQHGSFKMCLNYRIRVLCCTSSSTTPTLSVTTSTSTATPTTTIETSTSTSTLTPTPTLISTTSSPSTTTHVTACELELCSWTDWFDVDFPSSGTSQGDFETYQHIRAAGKEVCQQPKQIECQAEDYPEISIEQVGQVVQCDVHYGLVCKNQDQHGSFKMCLNYRIRVLCCRPNPDCVQTITPTTSPTTTISTGTSSSTTPTLSVTTSTSTATPTTTIETSTSTSTLTPTPTLISTTSSPSTTTHVTACELELCSWTD", "length": 2735, "header": "tr|A0A8V0ZVI7-1|A0A8V0ZTK4_CHICK Computationally mapped isoform of VWFD domain-containing protein OS=Gallus gallus OX=9031 GN=MUC5ACL PE=1 SV=1 CANONICAL=A0A8V0ZTK4-1" }, "locus": { "chromosome": "5", "start_pos": 14407924, "end_pos": 14383622, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010057390.1", "url": "https://www.ensembl.org/id/ENSGALT00010057390.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034877.1", "url": "https://www.ensembl.org/id/ENSGALP00010034877.1" } ] } }, { "isoform_ac": "A0A8V0ZWW5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTK4/entry#A0A8V0ZWW5-1", "sequence": { "sequence": "MEGIYSKLQNILMAHFESAAGNPSHNGRVCSTWGNFHFKNFDGDIFYFPGVCNYIFASNCKSPYEDFNIQIRRTMVENATVITHVIMRLEGAVVELTRTSVLVNGKQIQMPYSHMGVLIERSNSYIKVSAKLGLTFLWNEEDALLVELDKKYANQTCGLCGDFNGIPTNNEFISQNAKLTAVQFGNRQKIDGPTEQCDDPIPSAASICKTVLTSEAFTSCNALVDVQDYIDTCIQDLCHCDTSMADFCMCNTFAEYSRQCAHAGGQPLNWRTSELSKSCPFNMQHQECGSPCSDTCSNPERSALCEDHCTDGCTCPPGMVFDDINGAGCIPRKECHCTYEGETYAPGTSFSSKCRSCTCAGGEWTCVTQSCPATCSIEGGSHITTYDEKYYSFYGDCSYVLTKLCDSNDFTVLGDIHKCGLTDTETCLKGVAISLSGGQTNIVIQPSGSVFVNMIYTQLPFSAANVTIFRPSSFFIILQTTFGLQLQIQIVPLMQLFINLDPSQKGQTCGLCGNFNDIQTDDFKTTSGVIEGTSAAFGNTWKTRADCPDAKITFENPCTLSIENDKYAQHWCGLLSDTTGPFAECHSTVNPEVYQKNCMFDTCNCENTEDCMCAALSSYVRACAAKGILLNGWRNKVCTKYTNTCPKSLEYTYNVDSCQPTCRSLSEPDVTCNIKFVPVDGCTCVNGTYMDESGKCVPAASCPCYYKGMPLSTGEVIHDNGVVCTCSYGKLSCIGEKPPPVCAPPMVYVDCGNATAGVTGAECQKSCQTLDMECYKTHCVSGCICPPNYVSDGKGGCIAAEECPCVHNGDSYRPGESIRVGCNNCTCRNRKWHCSEEPCLETCSVYGDGHYTTFDGKRFDFEGDCEYVLIQNYCGRKGLNQGTFRVITENIPCGTTGTTCSKSIKVFLGNYELVLSDGHSDVIQRSPGGEMPFQIRSMGIYMVVDTTVGLILMWDKKTSIFIKLSPSFQGHVCGLCGNYDGNGNNDFTTRSQSVVGNVLEFANSWKVSSTCPNANQTKDPCTANPYRKSWAQKQCSIITSEVFAKCHSQVEPNEYYQACVDDACACDTGGDCECFCTAVAAYAQACNELDICISWRTPSICPLFCDYYNPQGECEWHYKPCGAPCMKTCNNPSGKCLHELRGLEGCYPHCPKNKPYFDEETMACVSNCGCYENGKHYKPGMQMPSKQNCQTCTILFCFTECVCIYEGRTYNYTDMIYNTTDGIGGCIVATCGPNGTLQRVVYDCPISTSPTTPFHFSTTPPATPLSITFISVGFQSIFGNQTNTIQKIKSLPKHQHRNNFTSSPTTSVCVHEVCQWSEWYDGSPLIPGFDGGDFETFSDLRAKGYEVCRDPKAVQCRAEKFPNIPLKDLGQRVECNTQSGLICYNKDQISTMCYNYEIRILCCVFVPCSSTSSITTPYETSTLITHTPVPEKTTTATSTIITTSSTTTETGSTTITSTSSETASTSPEAIRTTPCQPKCKWSKWYDVHFPTLHNKGDYETYQDIRSAGKAICRNPEKIQCRAEKYPHKSIEEIGQVVHCNVTYGLICRNEDQKGELHICLNYQVKVFCCDDYSHCQTRVTPTVPEEITTTITQSPATTTSETSTFTTKLTSPVTISPTTSALCVKEECDWSVWYDVSYPEPGYNDGDFDTVQNIRKQGYEVCANRMAVECRAVRFPNTPYQLLEQHITCNTKEGLICYNKDQLPPICYNYEVRFKCCKNVTVPCQTTKTPYSTTKKPTTSTISTTQTTPYTETSTMTYTPKIQTKHKTTTIETIPPRTENIHSETTSTPKQTPSRPPLLSSPLPAHLPPRPTLPPANLNSAPGPTGLTLTSPPRGQARETLKPTSTSALPGRKSVNSQNKLSARPRTTPRFPSNKSDRWCSVTFTTDWCARTRTSTAVLRCASTTGSASSAAGLTPTACRPLLLPPVPPPPSPQAPPPPLHPPSQSQPPPPPLRPLQQ", "length": 1958, "header": "tr|A0A8V0ZWW5-1|A0A8V0ZTK4_CHICK Computationally mapped isoform of VWFD domain-containing protein OS=Gallus gallus OX=9031 GN=MUC5ACL PE=1 SV=1 CANONICAL=A0A8V0ZTK4-1" }, "locus": { "chromosome": "5", "start_pos": 14407924, "end_pos": 14385832, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010057369.1", "url": "https://www.ensembl.org/id/ENSGALT00010057369.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034866.1", "url": "https://www.ensembl.org/id/ENSGALP00010034866.1" } ] } }, { "isoform_ac": "A0A8V1A122-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTK4/entry#A0A8V1A122-1", "sequence": { "sequence": "MEGIYSKLQNILMAHFESAAGNPSHNGRVCSTWGNFHFKNFDGDIFYFPGVCNYIFASNCKSPYEDFNIQIRRTMVENATVITHVIMRLEGAVVELTRTSVLVNGKQIQMPYSHMGVLIERSNSYIKVSAKLGLTFLWNEEDALLVELDKKYANQTCGLCGDFNGIPTNNEFISQNAKLTAVQFGNRQKIDGPTEQCDDPIPSAVLMNCSSEFASICKTVLTSEAFTSCNALVDVQDYIDTCIQDLCHCDTSMADFCMCNTFAEYSRQCAHAGGQPLNWRTSELCPKSCPFNMQHQECGSPCSDTCSNPERSALCEDHCTDGCTCPPGMVFDDINGAGCIPRKECHCTYEGETYAPGTSFSSKCRSCTCAGGEWTCVTQSCPATCSIEGGSHITTYDEKYYSFYGDCSYVLTKLCDSNDFTVLGDIHKCGLTDTETCLKGVAISLSGGQTVIVSTVYLKLNYFSLSTANVTIFRPSSFFIILQTTFGLQLQIQIVPLMQLFINLDPSQKGQTCGLCGNFNDIQTDDFKTTSGVIEGTSAAFGNTWKTRADCPDAKITFENPCTLSIENDKYAQHWCGLLSDTTGPFAECHSTVNPENCMFDTCNCENTEDCMCAALSSYVRACAAKGILLNGWRNKVCTKYTNTCPKSLEYTYNVDSCQPTCRSLSEPDVTCNIKFVPVDGCTCVNGTYMDESGKCVPAASCPCYYKGMPLSTGEVIHDNGVVCTCSYGKLSCIGEKPPPVCAPPMVYVDCGNATAGVTGAECQKSCQTLDMECYKTHCVSGCICPPNYVSDGKGGCIAAEECPCVHNGDSYRPGESIRVGCNNCTCRNRKWHCSEEPCLETCSVYGDGHYTTFDGKRFDFEGDCEYVLIQNYCGRKGLNQGTFRVITENIPCGTTGTTCSKSIKVFLGNYELVLSDGHSDVIQRSPGGEMPFQIRSMGIYMVVDTTVGLILMWDKKTSIFIKLSPSFQGHVCGLCGNYDGNGNNDFTTRSQSVVGNVLEFANSWKVSSTCPNANQTKDPCTANPYRKSWAQKQCSIITSEVFAKCHSQVEPNEYYQACVDDACACDTGGDCECFCTAVAAYAQACNELDICISWRTPSICPLFCDYYNPQGECEWHYKPCGAPCMKTCNNPSGKCLHELRGLEGCYPHCPKNKPYFDEETMACVSNCGCYENGKHYKPGMQMPSKQNCQTCTILFCFTECVCIYEGRTYNYTDMIYNTTDGIGGCIVATCGPNGTLQRVVYDCPISTSPTTPFHFSTTPPATASTVCVHEVCQWSEWYDGSPLIPGFDGGDFETFSDLRAKGYEVCRDPKAVQCRAEKFPNIPLKDLGQRVECNTQSGLICYNKDQISTMCYNYEIRILCCVFVPCSSTSSITTPYETSTLITHTPVPEKTTTATSTIITTSSTTTETGSTTITSTSSETASTSPEAIRTTPCQPKCKWSKWYDVHFPTLHNKGDYETYQDIRSAGKAICRNPEKIQCRAEKYPHKSIEEIGQVVHCNVTYGLICRNEDQKGELHICLNYQVKVFCCDDYSHCQTRVTPTVPEEITTTITQSPATTTSETSTFTTKLTSPVTISPTTSALCVKEECDWSVWYDVSYPEPGYNDGDFDTVQNIRKQGYEVCANRMAVECRAVRFPNTPYQLLEQHITCNTKEGLICYNKDQLPPICYNYEVRFKCCKNVTVPCQTTKTPYSTTKKPTTSTISTTQTTPYTETSTMTYTPKIQTKHKTTTIETIPPRTENIHSETTSTPKQSIQTETKTTTILTVTTSTSTATPTTTIETSTSTSTLTPTPTLISTTSSPSTTTHVTACELELCSWTDWFDVDFPSSGTSQGDFETYQHIRAAGKEVCQQPKQIECQAEDYPEISIEQVGQVVQCDVHYGLVCKNQDQHGSFKMCLNYRIRVLCCRPNPDCVQTITPTTSPTTTISTGTSSSTTPTLSVTTSTSTATPTTTIETSTSTSTLTPTPTLISTTSSPSTTTHVTACELELCSWTDWFDVDFPSSGTSQGDFETYQHIRAAGKEVCQQPKQIECQAEDYPEISIEQVGQVVQCDVHYGLVCKNQDQHGSFKMCLNYRIRVLCCRPNPDCVQTITPTTSPTTTISTGTSSSTTPTLSVTTSTSTATPTTTIETSTSTSTLTPTPTLISTTSSPSTTTHVTACELELCSWTDWFDVDFPSSGTSQGDFETYQHIRAAGKEVCQQPKQIECQAEDYPEISIEQVGQVVQCDVHYGLVCKNQDQHGSFKMCLNYRIRVLCCRPNPDCVQTITPTTSPTTTISTGTSSSTTPTLSVTTSTSTATPTTTIETSTSTSTLTPTPTLISTTSSPSTTTHVTACELELCSWTDWFDVDFPSSGTSQGDFETYQHIRAAGKEVCQQPKQIECQAEDYPEISIEQVGQVVQCDVHYGLVCKNQDQHGSFKMCLNYRIRVLCCRPNPDCVQTITPTTSPTTTISTGTSSSTTPTLSVTTSTSTATPTTTIETSTSTSTLTPTPTLISTTSSPSTTTHVTACELELCSWTDWFDVDFPSSGTSQGDFETYQHIRAAGKEVCQQPKQIECQAEDYPEISIEQVGQVVQIRVLCCRPNPDCVQTITPTTSPTTTISTGTSSSTTPTLSVTTSTSTATPTTTIETSTSTSTLTPTPTLISTTSSPSTTTHVTACELELCSWTDWFDVDFPSSGTSQGDFETYQHIRAAGK", "length": 2689, "header": "tr|A0A8V1A122-1|A0A8V0ZTK4_CHICK Computationally mapped isoform of VWFD domain-containing protein OS=Gallus gallus OX=9031 GN=MUC5ACL PE=1 SV=1 CANONICAL=A0A8V0ZTK4-1" }, "locus": { "chromosome": "5", "start_pos": 14407924, "end_pos": 14383541, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010057417.1", "url": "https://www.ensembl.org/id/ENSGALT00010057417.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034890.1", "url": "https://www.ensembl.org/id/ENSGALP00010034890.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1574, "start_aa": "Thr", "end_pos": 1574, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1574", 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"A0A8V0ZTD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTD3" } ] } ], "protein_names": [ { "name": "Cell division cycle associated 9", "type": "synonym", "evidence": [ { "id": "A0A8V0ZTD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTD3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTD3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTD3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CDCA9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTD3", "locus": { "chromosome": "11", "start_pos": 7372868, "end_pos": 7380271, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010023513", "url": "https://www.ensembl.org/id/ENSGALG00010023513" } ] } } ], "crossref": [ { "id": "A0A8V0ZTD3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZTD3", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR018851", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018851", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018867", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018867", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046466", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046466", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZN46", "url": "https://www.orthodb.org/?gene=A0A8V0ZN46", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZN52", "url": "https://www.orthodb.org/?gene=A0A8V0ZN52", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZTD3", "url": "https://www.orthodb.org/?gene=A0A8V0ZTD3", 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"MPPRKAPAKRRSTDSGVERDRGALSQEKKDQRIALFLSDFDQQAKESIREMKKELDLLLQMAEKAFMVELLKMPTAIRKMKRKDLLNLQEGEEVALAAAATDCALQDVPSPKVTRTNSKKVKVTTIVEYEDAKYTSAKKIPKKVSKSKSLVSLSSGLNSKPHSLSRSVYSSTSVSEAVKTPASDCSATNFKAMPKVSKSAGLQQAVSRTVPTSERVQGMVLRSKSVPQDKMVPFVNIPLADGQTLCMAGGDLRNIDVQLLNQDTVQHIHNLVVSLNQQTCIPTHSSTLSCEINVPGADSSCVFLLRLSLSWLAEVGRRKGEGGVGRGQLLYTDKGVEECLENMYMCTEKNRSISFSF", "length": 357, "header": "tr|A0A8V0ZTD3-1|A0A8V0ZTD3_CHICK Isoform 1 of Cell division cycle associated 9 OS=Gallus gallus OX=9031 GN=CDCA9 PE=3 SV=1 CANONICAL=A0A8V0ZTD3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZN46-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTD3/entry#A0A8V0ZN46-1", "sequence": { "sequence": "MPPRKAPAKRRSTDSGVERDRGALSQEKKDQRIALFLSDFDQQAKESIREMKKELDLLLQMAEKAFMVELLKMPTAIRKMKRKDLLNLQEGEEVALAAAATDCALQDVPSPKVTRTNSKKVKVTTIVEYEDAKYTSAKKIPKKVSKSKSLVSLSSGLNSKPHSLSRSVYSSTSVSEAVKTPASDCSATNFKAMPKVSKSAGLQQAVSRTVPTSERVQGMVLRSKSVPQDKMVPFVNIPLADGQTLCMAGGDLRNIDVQLLNQDTVQHIHNLVSELTVLCGKATAKSS", "length": 287, "header": "tr|A0A8V0ZN46-1|A0A8V0ZN46_CHICK Computationally mapped isoform of Cell division cycle associated 9 OS=Gallus gallus OX=9031 GN=CDCA9 PE=3 SV=1 CANONICAL=A0A8V0ZTD3-1" }, "locus": { "chromosome": "11", "start_pos": 7380161, "end_pos": 7374592, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010057268.1", "url": "https://www.ensembl.org/id/ENSGALT00010057268.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034822.1", "url": "https://www.ensembl.org/id/ENSGALP00010034822.1" } ] } }, { "isoform_ac": "A0A8V0ZN52-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTD3/entry#A0A8V0ZN52-1", "sequence": { "sequence": "MPPRKAPAKRRSTDSGVERDRGALSQEKKDQRIALFLSDFDQQAKESIREMKKELDLLLQMAEKAFMVELLKMPTAIRKMKRKDLLNLQEGEEVALAAAATDCALQDVPSPKVTRTNSKKVKVTTIVEYEDAKYTSAKKIPKKVSKSKSLVSLSSGLNSKPHSLSRSVYSSTSVSEAVKTPASDCSATNFKAMPKVSKSAGLQQAVSRTVPTSERVQGMVLRSKSVPQDKMVPFVNIPLADGQTLCMAGGDLRNIDVQLLNQDTVQHIHNLVVSLNQQTCIPTHSSTLSCEINVPGADSSCVFLLRLNFLR", "length": 311, "header": "tr|A0A8V0ZN52-1|A0A8V0ZN52_CHICK Computationally mapped isoform of Cell division cycle associated 9 OS=Gallus gallus OX=9031 GN=CDCA9 PE=3 SV=1 CANONICAL=A0A8V0ZTD3-1" }, "locus": { "chromosome": "11", "start_pos": 7380161, "end_pos": 7373987, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010057275.1", "url": "https://www.ensembl.org/id/ENSGALT00010057275.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034827.1", "url": "https://www.ensembl.org/id/ENSGALP00010034827.1" } ] } }, { "isoform_ac": "A0A8V0ZTD3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTD3/entry#A0A8V0ZTD3-1", "sequence": { "sequence": "MPPRKAPAKRRSTDSGVERDRGALSQEKKDQRIALFLSDFDQQAKESIREMKKELDLLLQMAEKAFMVELLKMPTAIRKMKRKDLLNLQEGEEVALAAAATDCALQDVPSPKVTRTNSKKVKVTTIVEYEDAKYTSAKKIPKKVSKSKSLVSLSSGLNSKPHSLSRSVYSSTSVSEAVKTPASDCSATNFKAMPKVSKSAGLQQAVSRTVPTSERVQGMVLRSKSVPQDKMVPFVNIPLADGQTLCMAGGDLRNIDVQLLNQDTVQHIHNLVVSLNQQTCIPTHSSTLSCEINVPGADSSCVFLLRLSLSWLAEVGRRKGEGGVGRGQLLYTDKGVEECLENMYMCTEKNRSISFSF", "length": 357, "header": "tr|A0A8V0ZTD3-1|A0A8V0ZTD3_CHICK Isoform 1 of Cell division cycle associated 9 OS=Gallus gallus OX=9031 GN=CDCA9 PE=3 SV=1 CANONICAL=A0A8V0ZTD3-1" }, "locus": { "chromosome": "11", "start_pos": 7380161, "end_pos": 7374955, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010057290.1", "url": "https://www.ensembl.org/id/ENSGALT00010057290.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034834.1", "url": "https://www.ensembl.org/id/ENSGALP00010034834.1" } ] } }, { "isoform_ac": "A0A8V0ZWS3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTD3/entry#A0A8V0ZWS3-1", "sequence": { "sequence": "MPPRKAPAKRRSTDSGVERDRGALSQEKKDQRIALFLSDFDQQAKESIREMKKELDLLLQMAEKAFMVELLKMPTAIRKMKRKDLLNLQEGEEVALAAAATDCALQDVPSPKVTRTNSKKVKVTTIVEYEDAKYTSAKKIPKKVSKSKSLVSLSSGLNSKPHSLSRSVYSSTSVSEAVKTPASDCSATNFKAMPKVSKSAGLQQAVSRTVPTSERVQGMVLRSKSVPQDKMVPFVNIPLADGQTLCMAGGDLRNIDVQLLNQDTVQHIHNLVDRLLRARKVFLGPDTG", "length": 288, "header": "tr|A0A8V0ZWS3-1|A0A8V0ZTD3_CHICK Computationally mapped isoform of Cell division cycle associated 9 OS=Gallus gallus OX=9031 GN=CDCA9 PE=3 SV=1 CANONICAL=A0A8V0ZTD3-1" }, "locus": { "chromosome": "11", "start_pos": 7380161, "end_pos": 7373109, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010057279.1", "url": "https://www.ensembl.org/id/ENSGALT00010057279.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034830.1", "url": "https://www.ensembl.org/id/ENSGALP00010034830.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": 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"url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTD3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTD3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTD3" } ], "pmid": "" }, { "name": "mitotic sister chromatid segregation", "id": "GO:0000070", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000070", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTD3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTD3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 350, "end_pos": 352, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZTD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTD3" }, { "id": "PF10512", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10512" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Borealin C-terminal", "eco_id": "ECO_0000259", "start_pos": 178, "end_pos": 277, "start_aa": "Val", "end_aa": "Gln", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZTD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTD3" }, { "id": "PF10444", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10444" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Borealin N-terminal", "eco_id": "ECO_0000259", "start_pos": 33, "end_pos": 87, "start_aa": "Ile", "end_aa": "Asn", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { 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"field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { 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"categories": [ "Protein" ] } ], "sequence": { "sequence": "MGETWPDSRHPPPPPPPPRPHFITAAAGPPHPVRPHPAMLRLLLLCAALGCGAGGDAAPLTFTMLQWTRVSNGNYAFWGNATLGGRLSHLLEDRNVTQVLPLEPPAGWARQQDMVANYLSYFSGIVQVFSKERPLNYTQNLHCRLGCCLFPNGTTCSFYEVSLNGTAFLTFHVPNATWKLRWPRKDPVATFAQQELMKYSETTHHLQHFLNTTCMDILWAQSPQTGKHRGRSHAPLVLGLILGVSAVVGMAVGIFLCTGGSC", "length": 262, "header": "tr|A0A8V0ZTD6-1|A0A8V0ZTD6_CHICK Isoform 1 of Protein C receptor OS=Gallus gallus OX=9031 GN=PROCR PE=4 SV=1 CANONICAL=A0A8V0ZTD6-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZTD6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTD6/entry#A0A8V0ZTD6-1", "sequence": { "sequence": "MGETWPDSRHPPPPPPPPRPHFITAAAGPPHPVRPHPAMLRLLLLCAALGCGAGGDAAPLTFTMLQWTRVSNGNYAFWGNATLGGRLSHLLEDRNVTQVLPLEPPAGWARQQDMVANYLSYFSGIVQVFSKERPLNYTQNLHCRLGCCLFPNGTTCSFYEVSLNGTAFLTFHVPNATWKLRWPRKDPVATFAQQELMKYSETTHHLQHFLNTTCMDILWAQSPQTGKHRGRSHAPLVLGLILGVSAVVGMAVGIFLCTGGSC", "length": 262, "header": "tr|A0A8V0ZTD6-1|A0A8V0ZTD6_CHICK Isoform 1 of Protein C receptor OS=Gallus gallus OX=9031 GN=PROCR PE=4 SV=1 CANONICAL=A0A8V0ZTD6-1" }, "locus": { "chromosome": "9", "start_pos": 4039715, "end_pos": 4038204, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010060022.1", "url": "https://www.ensembl.org/id/ENSGALT00010060022.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036782.1", "url": "https://www.ensembl.org/id/ENSGALP00010036782.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-9769739", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9769739", "resource": "Reactome", "description": "Regulation of clotting cascade" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTD6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTD6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "negative regulation of coagulation", "id": "GO:0050819", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050819", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTD6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTD6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "signaling receptor activity", "id": "GO:0038023", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038023", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTD6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTD6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 136, "end_pos": 138, "annotation": "n_glycosylation_sequon" }, { "start_pos": 152, "end_pos": 154, "annotation": "n_glycosylation_sequon" }, { "start_pos": 164, "end_pos": 166, "annotation": "n_glycosylation_sequon" }, { "start_pos": 175, "end_pos": 177, "annotation": "n_glycosylation_sequon" }, { "start_pos": 211, "end_pos": 213, "annotation": "n_glycosylation_sequon" }, { "start_pos": 80, "end_pos": 82, "annotation": "n_glycosylation_sequon" }, { "start_pos": 95, "end_pos": 97, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 136, "end_pos": 138 }, { "start_pos": 152, "end_pos": 154 }, { "start_pos": 164, "end_pos": 166 }, { "start_pos": 175, "end_pos": 177 }, { "start_pos": 211, "end_pos": 213 }, { "start_pos": 80, "end_pos": 82 }, { "start_pos": 95, "end_pos": 97 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZTE2-1", "uniprot_ac": "A0A8V0ZTE2", "uniprot_id": "A0A8V0ZTE2_CHICK", "mass": { "chemical_mass": 46389.0, "monoisotopic_mass": 46389.0 }, "refseq": { "ac": "NP_001180598", "name": "lupus La protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001180598" }, "gene_names": [ { "name": "SSB", "type": "recommended", "evidence": [ { "id": "A0A8V0ZTE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTE2" } ] }, { "name": "SSB", "type": "synonym", "evidence": [ { "id": "NP_001180598", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001180598" } ] }, { "name": "UBP", "type": "synonym", "evidence": [ { "id": "NP_001180598", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001180598" } ] } ], "protein_names": [ { "name": "Sjogren syndrome antigen B (autoantigen La)", "type": "synonym", "evidence": [ { "id": "NP_001180598", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001180598" } ] }, { "name": "Sjogren syndrome antigen B", "type": "synonym", "evidence": [ { "id": "A0A8V0ZTE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTE2/entry#names_and_taxonomy" } ] }, { "name": "lupus La protein", "type": "synonym", "evidence": [ { "id": "NP_001180598", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001180598" } ] }, { "name": "untranslated region binding-protein", "type": "synonym", "evidence": [ { "id": "NP_001180598", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001180598" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: HAEK01016126.1, ERR2368565.139004.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000236.1. On Jan 20, 2018 this sequence version replaced NP_989911.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001180598", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001180598" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTE2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTE2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SSB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTE2", "locus": { "chromosome": "7", "start_pos": 18198553, "end_pos": 18206520, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010023544", "url": "https://www.ensembl.org/id/ENSGALG00010023544" } ] } } ], "crossref": [ { "id": "A0A8V0ZTE2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZTE2", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd08028", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08028", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12291", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12291", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12541", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12541", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "395268", "url": "https://www.ncbi.nlm.nih.gov/gene/395268", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002344", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002344", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006630", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006630", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014886", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014886", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036388", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036388", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036390", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036390", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045180", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045180", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:395268", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395268", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QFERSIY", "url": "https://omabrowser.org/oma/group/QFERSIY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZTE2", "url": "https://www.orthodb.org/?gene=A0A8V0ZTE2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZVF8", "url": "https://www.orthodb.org/?gene=A0A8V0ZVF8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22792", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22792", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22792:SF166", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22792:SF166", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00076", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00076", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF05383", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05383", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08777", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08777", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001180598", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001180598", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZTE2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTE2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZTE2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTE2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZVF8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVF8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZVF8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVF8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAENGDGENMSILESKICQQIEYYFGNHNLPRDKFLKEQIKLDDGWVPLEVMIKFNRLSRLSKDFGVIVEALRKSKTGLMEINEDKTKIRRSPNKPLPELNDQYKAAIKNRSVYVKGFPLDATLDDIKEWLEDKGPVENIQMRRTLQKTFKGSIFAVFDSVESAKKFTEIPNQKYKDTELIVLFKEEYCTKKNEERKQNKVEAKARAKQEKEEKQKQAADAEMKSLEEKTGCLLKFSGDLDDQTCREDLHVVFSDHGEIKWIHFVRGAKEGIILFKDAAKEALEKAKEAHNGNLQLRNKDVTWELLEGDAEKEALKKILEDQQELLKQKGKGRKLKGRGGKMAQGAHKGKVQFQGKKIKFENEEEGEDDTKTEPVSPKKRPLEETEKEESAPKQLKTENGDGAQ", "length": 404, "header": "tr|A0A8V0ZTE2-1|A0A8V0ZTE2_CHICK Isoform 1 of Sjogren syndrome antigen B OS=Gallus gallus OX=9031 GN=SSB PE=1 SV=1 CANONICAL=A0A8V0ZTE2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZTE2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTE2/entry#A0A8V0ZTE2-1", "sequence": { "sequence": "MAENGDGENMSILESKICQQIEYYFGNHNLPRDKFLKEQIKLDDGWVPLEVMIKFNRLSRLSKDFGVIVEALRKSKTGLMEINEDKTKIRRSPNKPLPELNDQYKAAIKNRSVYVKGFPLDATLDDIKEWLEDKGPVENIQMRRTLQKTFKGSIFAVFDSVESAKKFTEIPNQKYKDTELIVLFKEEYCTKKNEERKQNKVEAKARAKQEKEEKQKQAADAEMKSLEEKTGCLLKFSGDLDDQTCREDLHVVFSDHGEIKWIHFVRGAKEGIILFKDAAKEALEKAKEAHNGNLQLRNKDVTWELLEGDAEKEALKKILEDQQELLKQKGKGRKLKGRGGKMAQGAHKGKVQFQGKKIKFENEEEGEDDTKTEPVSPKKRPLEETEKEESAPKQLKTENGDGAQ", "length": 404, "header": "tr|A0A8V0ZTE2-1|A0A8V0ZTE2_CHICK Isoform 1 of Sjogren syndrome antigen B OS=Gallus gallus OX=9031 GN=SSB PE=1 SV=1 CANONICAL=A0A8V0ZTE2-1" }, "locus": { "chromosome": "7", "start_pos": 18203772, "end_pos": 18198902, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010057323.1", "url": "https://www.ensembl.org/id/ENSGALT00010057323.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034845.1", "url": "https://www.ensembl.org/id/ENSGALP00010034845.1" } ] } }, { "isoform_ac": "A0A8V0ZVF8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTE2/entry#A0A8V0ZVF8-1", "sequence": { "sequence": "MAENGDGENMSILESKICQQIEYYFGNHNLPRDKFLKEQIKLDDGWVPLEVMIKFNRLSRLSKDFGVIVEALRKSKTGLMEINEDKTKIRRSPNKPLPELNDQYKAAIKNRSVYVKGFPLDATLDDIKEWLEDKGPVENIQMRRTLQKTFKGSIFAVFDSVESAKKFTEIPNQKYKDTELIVLFKEEYCTKKNEERKQNKVEAKARAKQ", "length": 209, "header": "tr|A0A8V0ZVF8-1|A0A8V0ZTE2_CHICK Computationally mapped isoform of Sjogren syndrome antigen B OS=Gallus gallus OX=9031 GN=SSB PE=1 SV=1 CANONICAL=A0A8V0ZTE2-1" }, "locus": { "chromosome": "7", "start_pos": 18203772, "end_pos": 18202089, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010057328.1", "url": "https://www.ensembl.org/id/ENSGALT00010057328.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034847.1", "url": "https://www.ensembl.org/id/ENSGALP00010034847.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:395268", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395268", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1S1V1-1", "protein_name": "Small RNA binding exonuclease protection factor La", "gene_name": "SSB", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAENGDNEKLAALEAKICHQIEYYFGDFNLPRDKFLKEQIKLDEGWVPLEIMIKFNRLNRLTTDFNVIIEALSKSKAELMEISEDKTKIRRSPSKPLPEVTDEYKNDLKNRSVYVKGFPTDATLDDIKDWLEDKGEILNIQMRRTLHKTFKGSIFAVFDSIESAKKFVKTPGQKYKDTDLLILFKEEYFAKKNEERKKHKIEAKLRAKQQQEKLKLAEHPEMRALEGKIGCLLKFCGNLDDQTSREDFHNLFARHGEIKWIDFVRGAKEGTILFKERAKEVLARARDAHHGNLQIRNKRVVWEVLRGDMERRALRKIIQDQQESLNKWKTRGRRFRGRGGRGGGRAGMAIRGRAQFQGRKPRFDHFEDRRAPFGRIKRAREERDDRMAPKQRKRAKRARYH", "length": 401 }, "evidence": [ { "id": "A0A8V0ZTE2", "url": "https://omabrowser.org/oma/group/A0A8V0ZTE2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3GU92-1", "protein_name": "Lupus La protein homolog", "gene_name": "Ssb", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAENGDNEKMAALEAKICHQIEYYFGDFNLPRDKFLKEQIKLDEGWVPLDIMIKFNRLNRLTTDFNVIVQALSKSKAKLMEVSADKTKIRRSPSRPLPEVTDEYKNDVKNRSVYIKGFPTDATLDDIKEWLDDKGQILNIQMRRTLHKTFKGSIFAVFDSIQSAKKFVDTPGQKYKDTSLLILFKEDYFAKKNEERKQSKVEAKLKAKQEHEGRHKSGSTETRPLEGKMGCLLKFSGDLDDQTCREDLHILFSNHGEIKWIDFVRGAKEGIILFKEKAKEALEKARSAHNGNLQLRNKKVTWKVLEGHAEKDAMKKIMEDQQESLNKWKSKGGGGGGRRFKGKGKGNRPPYGGAPKGRGQFQGRRTRFDDDDHHHHRRGPMKRGRDGRDREEPASKHKKRENGARDK", "length": 407 }, "evidence": [ { "id": "A0A8V0ZTE2", "url": "https://omabrowser.org/oma/group/A0A8V0ZTE2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P05455-1", "protein_name": "Lupus La protein", "gene_name": "SSB", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAENGDNEKMAALEAKICHQIEYYFGDFNLPRDKFLKEQIKLDEGWVPLEIMIKFNRLNRLTTDFNVIVEALSKSKAELMEISEDKTKIRRSPSKPLPEVTDEYKNDVKNRSVYIKGFPTDATLDDIKEWLEDKGQVLNIQMRRTLHKAFKGSIFVVFDSIESAKKFVETPGQKYKETDLLILFKDDYFAKKNEERKQNKVEAKLRAKQEQEAKQKLEEDAEMKSLEEKIGCLLKFSGDLDDQTCREDLHILFSNHGEIKWIDFVRGAKEGIILFKEKAKEALGKAKDANNGNLQLRNKEVTWEVLEGEVEKEALKKIIEDQQESLNKWKSKGRRFKGKGKGNKAAQPGSGKGKVQFQGKKTKFASDDEHDEHDENGATGPVKRAREETDKEEPASKQQKTENGAGDQ", "length": 408 }, "evidence": [ { "id": "A0A8V0ZTE2", "url": "https://omabrowser.org/oma/group/A0A8V0ZTE2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P10881-1", "protein_name": "Lupus La protein homolog", "gene_name": "SSB", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAENGDNEKMAALEAKICHQIEYYFGDFNLPRDKFLKEQIKLDEGWVPLEIMIKFNRLNRLTTDFNVIVEALSKSKAELMEISEDKTKIRRSPSKPLPEVTDEYKNDVKNRSVYIKGFPTDAALDDIKEWLEDKGQVLNIQMRRTLHKAFKGSIFAVFDSIESAKKFVETPGQKYKDTDLLILFKEDYFTKKNEERKQNKMEAKLRAKQEQEEKQKLAENAEMKSLEEKIGCLLKFSGDLDDQTCREDLHTLFSNHGEIKWIHFVRGAKEGIILFKEKAKEALDKAKEANNGNLQLRNKEVTWEVLEGDVEKEALKKIIEDQQESLNKWKSKGRRFKGKGKGNKAAQAGSAKGKVQFQGKKTKFDSDDERDENGASRAVKRAREETDKEPPSKQQKTENGAGDQ", "length": 404 }, "evidence": [ { "id": "A0A8V0ZTE2", "url": "https://omabrowser.org/oma/group/A0A8V0ZTE2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P32067-1", "protein_name": "Lupus La protein homolog", "gene_name": "Ssb", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAENGDNEKMTALEAKICHQIEYYFGDFNLPRDKFLKEQIKLDEGWVPLETMIKFNRLNRLTTDFNVIVQALSKSKAKLMEVSADKTKIRRSPSRPLPEVTDEYKNDVKNRSVYIKGFPTDATLDDIKEWLDDKGQILNIQMRRTLHKTFKGSIFAVFDSIQSAKKFVEIPGQKYKDTNLLILFKEDYFAKKNEERKQSKVEAKLKAKQEHEGRHKPGSTETRALEGKMGCLLKFSGDLDDQTCREDLHFLFSNHGEIKWVDFARGAKEGIILFKEKAKEALEKARNANNGNLLLRNKKVTWKVLEGHAEKEALKKITDDQQESLNKWKSKGGHAGGRFKGSHVFTAARRFKGKGKGNRPGYAGAPKGRGQFHGRRTRFDDDDRRRGPMKRGRDGRDREEPASKHKKRENGARDK", "length": 415 }, "evidence": [ { "id": "A0A8V0ZTE2", "url": "https://omabrowser.org/oma/group/A0A8V0ZTE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P38656-1", "protein_name": "Lupus La protein homolog", "gene_name": "Ssb", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAENGDNEKMAALEAKICHQIEYYFGDFNLPRDKFLKEQIKLDEGWVPLETMIKFNRLNRLTTDFNVIVQALSKSKANLMEVSADKTKIRRSPSRPLPEVTDEYKNDVKNRSVYIKGFPTDATLDDIKEWLDDKGQILNIQMRRTLHKTFKGSIFAVFDSIQSAKKFVDTPGQKYKDTNLLILFKEDYFAKKNEERKQSKVEAKLKAKQEHEGRHKPGSTETRALEGKMGCLLKFSGDLDDQTCREDFHFLFSNHGEIKWIDFVRGAKEGIILFKEKAKDALEKARSANNGNLLLRNKKVTWKVLEGHAEKDAMKKITDDQQESLNKWKSKGGHAARRFKGSHVFTAARRFKGRGKGNRPAYAGAPKGRGQFQGRRTRFDDDDHRRGPVKRGIDGRDREEPASKHKKRENGARDK", "length": 415 }, "evidence": [ { "id": "A0A8V0ZTE2", "url": "https://omabrowser.org/oma/group/A0A8V0ZTE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q54TG6-1", "protein_name": "Lupus La protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSEETSTQILKQVEYYFSDSNFPRDKFLRSEAAKNVDNYISIDVIASFNRMKTISTDLQLITEALKKSTRLQVSEDGKMVRRLDPLPENIDCGKTLYSKGWPEDTTIEKVQEFFNANGGYKVVSVRLRKKSDKSFKGSFLADFETEEIVNKIITEAPKLGEKELIYQTFKQFSDEKKDEKEKFFASTNGDKKRKAKKEADRENGDDDDNDGDNKDVKKEVEEEEVMIPGVILCFKGVGKGLHRGDIKEIFSQYGEVQFVGYNSDEENGSVRYKTAESCKRAIESLTETKKEIGGQIPTYNLLEGEEEKKEWEKIIERKKNAAKNGGFKKGGFKKGGFKKGGFKKGGNFKKVKKE", "length": 354 }, "evidence": [ { "id": "A0A8V0ZTE2", "url": "https://omabrowser.org/oma/group/A0A8V0ZTE2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q93ZV7-1", "protein_name": "La protein 1", "gene_name": "LA1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSIPCLTEETAKTVLRQVEFYFSDSNLPIDDFLKKTVTESEDGLVSLALICSFSKMRGYLKLGDSKGDDIPEDTIKAVADTLRTSSALKISDDGKKVGRSTELLKLEDLIEQLNARTVAASPFSYDVKREDVESFFSQYGKVNSVRMPRHVAESRIFSGVALVEFPTEEDAQNVMKQNLVFAGQELELKPKKEFDNEREKDEVKFANYQPQKGSANQKNGSDHKNNSAYEPDYPKGLIISFTLKRSAEEGTTEQKSSEEPTDKTMEESETKPADTPDADKENTGEVQAEGAEDEDDEKEEKGALATHKDNKDVVLREDLKAVFGKFGDVKFVDFKMGSETGYLRFDEPEASQKARAAAVLANEGGLAVKNFIAVLEPVIGEAEKEYWTLLRSKDRFDKGGRGGRGGRRGGRFGRKRGSDSPGGRWNKSQKVEA", "length": 433 }, "evidence": [ { "id": "A0A8V0ZTE2", "url": "https://omabrowser.org/oma/group/A0A8V0ZTE2/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 9, "go_terms": [ { "name": "protein localization to cytoplasmic stress granule", "id": "GO:1903608", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903608", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTE2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTE2" } ], "pmid": "" }, { "name": "IRES-dependent viral translational initiation", "id": "GO:0075522", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0075522", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTE2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTE2" } ], "pmid": "" }, { "name": "tRNA export from nucleus", "id": "GO:0006409", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006409", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTE2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTE2" } ], "pmid": "" }, { "name": "tRNA processing", "id": "GO:0008033", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008033", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTE2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTE2" } ], "pmid": "" }, { "name": "positive regulation of translation", "id": "GO:0045727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045727", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTE2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTE2" } ], "pmid": "" }, { "name": "tRNA 5'-leader removal", "id": "GO:0001682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001682", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTE2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTE2" } ], "pmid": "" }, { "name": "tRNA 3'-end processing", "id": "GO:0042780", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042780", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTE2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTE2" } ], "pmid": "" }, { "name": "nuclear histone mRNA catabolic process", "id": "GO:0071045", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071045", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTE2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTE2" } ], "pmid": "" }, { "name": "RNA processing", "id": "GO:0006396", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006396", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTE2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTE2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "sequence-specific mRNA binding", "id": "GO:1990825", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990825", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTE2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTE2" } ], "pmid": "" }, { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTE2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTE2" } ], "pmid": "" }, { "name": "tRNA binding", "id": "GO:0000049", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000049", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTE2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTE2" } ], "pmid": "" }, { "name": "poly(U) RNA binding", "id": "GO:0008266", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008266", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTE2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTE2" } ], "pmid": "" }, { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTE2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTE2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTE2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTE2" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTE2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTE2" } ], "pmid": "" }, { "name": "cytoplasmic stress granule", "id": "GO:0010494", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010494", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTE2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTE2" } ], "pmid": "" }, { "name": "ribonucleoprotein complex", "id": "GO:1990904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990904", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTE2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTE2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 110, "end_pos": 112, "annotation": "n_glycosylation_sequon" }, { "start_pos": 9, "end_pos": 11, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZTE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTE2" }, { "id": "PS50961", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50961" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "HTH La-type RNA-binding", "eco_id": "ECO_0000259", "start_pos": 7, "end_pos": 99, "start_aa": "Gly", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZTE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTE2" }, { "id": "PS50102", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50102" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RRM", "eco_id": "ECO_0000259", "start_pos": 111, "end_pos": 187, "start_aa": "Arg", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZTE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTE2" }, { "id": "PS51939", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51939" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "XRRM", "eco_id": "ECO_0000259", "start_pos": 227, "end_pos": 347, "start_aa": "Glu", "end_aa": "His", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 110, "end_pos": 112 }, { "start_pos": 9, "end_pos": 11 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": 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0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZTE7-1", "uniprot_ac": "A0A8V0ZTE7", "uniprot_id": "A0A8V0ZTE7_CHICK", "mass": { "chemical_mass": 48519.0, "monoisotopic_mass": 48519.0 }, "refseq": {}, "gene_names": [ { "name": "SGPP2", "type": "recommended", "evidence": [ { "id": "A0A8V0ZTE7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTE7" } ] } ], "protein_names": [ { "name": "Sphingosine-1-phosphate phosphatase 2", "type": "synonym", "evidence": [ { "id": "A0A8V0ZTE7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTE7/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTE7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTE7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SGPP2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTE7", "locus": { "chromosome": "9", "start_pos": 7661059, "end_pos": 7635192, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010023552", "url": "https://www.ensembl.org/id/ENSGALG00010023552" } ] } } ], "crossref": [ { "id": "A0A8V0ZTE7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZTE7", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd03388", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03388", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "424813", "url": "https://www.ncbi.nlm.nih.gov/gene/424813", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000326", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000326", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036938", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036938", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:424813", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424813", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KFMVGIV", "url": "https://omabrowser.org/oma/group/KFMVGIV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZN71", "url": "https://www.orthodb.org/?gene=A0A8V0ZN71", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZTE7", "url": "https://www.orthodb.org/?gene=A0A8V0ZTE7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14969", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14969", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14969:SF14", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14969:SF14", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01569", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01569", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-9845614", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9845614", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZN71", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN71", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZN71-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN71-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZTE7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTE7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZTE7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTE7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MARLLGTLRGSQPVARFQRCCGLFPAGEEGGGDPAEGVRSSVVCNGGGAGGRRGAGAAGCGAPNGVRGGRGPQGCVQKYVVKNYFYYYLFKFSAALGEEIFYITFLPFIYWNIDHSVSRRMIIIWSIVMYIGQVSKDILKWPRPLSPPVVKLEMRTDAEYGMPSTHAMAATAISFSFFITTTNQYKYPFELGLTAAFVFSTLVCLSRLYTGMHTVLDVIGGALISAVLLVLLYPVWDSIDHVLLTSPFCPLLSIAVPLLLCYNYPKLDYYSPTRGDTTTILGAGAGATVGFWLNNQYVAPAHVGSTMAFPLITSTVVVLMLARFLVGLLVILLTRQLMKNVVLRVLCYCYTFPIADLDARRRLEVEAASHTEQPVLCPARRHMGPEGTAVWLQDYPHVHCSGGTVVYPATDEHMTTVQKKSSTPSFCSHSLSICSNQLSYFMQ", "length": 443, "header": "tr|A0A8V0ZTE7-1|A0A8V0ZTE7_CHICK Isoform 1 of Sphingosine-1-phosphate phosphatase 2 OS=Gallus gallus OX=9031 GN=SGPP2 PE=4 SV=1 CANONICAL=A0A8V0ZTE7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZN71-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTE7/entry#A0A8V0ZN71-1", "sequence": { "sequence": "MARLLGTLRGSQPVARFQRCCGLFPAGEEGGGDPAEGVRSSVVCNGGGAGGRRGAGAAGCGAPNGVRGGRGPQGCVQKYVVKNYFYYYLFKFSAALGEEIFYITFLPFIYWNIDHSVSRRMIIIWSIVMYIGQVSKDILKWPRPLSPPVVKLEMRTDAEYGMPSTHAMAATAISFSFFITTTNQYKYPFELGLTAAFVFSTLVCLSRLYTGMHTVLDVIGGALISAVLLVLLYPVWDSIDHVLLTSPFCPLLSIAVPLLLCYNYPKLDYYSPTRGDTTTILGAGAGATVGFWLNNQYVAPAHVGSTMAFPLITSTVVVLMLARFLVGLLVILLTRQLMKNVVLRVLCYCYTFPIADLDARRRLEVEVPYKFVTYSSVGFTATVIVPLLHELLGLI", "length": 395, "header": "tr|A0A8V0ZN71-1|A0A8V0ZN71_CHICK Computationally mapped isoform of Sphingosine-1-phosphate phosphatase 2 OS=Gallus gallus OX=9031 GN=SGPP2 PE=4 SV=1 CANONICAL=A0A8V0ZTE7-1" }, "locus": { "chromosome": "9", "start_pos": 7657417, "end_pos": 7635228, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010057332.1", "url": "https://www.ensembl.org/id/ENSGALT00010057332.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034848.1", "url": "https://www.ensembl.org/id/ENSGALP00010034848.1" } ] } }, { "isoform_ac": "A0A8V0ZTE7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTE7/entry#A0A8V0ZTE7-1", "sequence": { "sequence": "MARLLGTLRGSQPVARFQRCCGLFPAGEEGGGDPAEGVRSSVVCNGGGAGGRRGAGAAGCGAPNGVRGGRGPQGCVQKYVVKNYFYYYLFKFSAALGEEIFYITFLPFIYWNIDHSVSRRMIIIWSIVMYIGQVSKDILKWPRPLSPPVVKLEMRTDAEYGMPSTHAMAATAISFSFFITTTNQYKYPFELGLTAAFVFSTLVCLSRLYTGMHTVLDVIGGALISAVLLVLLYPVWDSIDHVLLTSPFCPLLSIAVPLLLCYNYPKLDYYSPTRGDTTTILGAGAGATVGFWLNNQYVAPAHVGSTMAFPLITSTVVVLMLARFLVGLLVILLTRQLMKNVVLRVLCYCYTFPIADLDARRRLEVEAASHTEQPVLCPARRHMGPEGTAVWLQDYPHVHCSGGTVVYPATDEHMTTVQKKSSTPSFCSHSLSICSNQLSYFMQ", "length": 443, "header": "tr|A0A8V0ZTE7-1|A0A8V0ZTE7_CHICK Isoform 1 of Sphingosine-1-phosphate phosphatase 2 OS=Gallus gallus OX=9031 GN=SGPP2 PE=4 SV=1 CANONICAL=A0A8V0ZTE7-1" }, "locus": { "chromosome": "9", "start_pos": 7660055, "end_pos": 7635228, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010057335.1", "url": "https://www.ensembl.org/id/ENSGALT00010057335.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034850.1", "url": "https://www.ensembl.org/id/ENSGALP00010034850.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:424813", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424813", "resource": "KEGG Pathway" }, { "id": "R-GGA-9845614", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9845614", "resource": "Reactome", "description": "Sphingolipid catabolism" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A5G2QIU3-1", "protein_name": "Sphingosine-1-phosphate phosphatase 2", "gene_name": "SGPP2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAELLRSLQDSQLVARFQRRCGLFPAPEEGLGESCADPVEGAARAPALEHLPAANGKGAGEPANGLRRVAVPQAYVQKYVVKNYFYYYLFRFSAALGQEVFYITFLPFTHWNIDPYLSRRLMIIWVLVMYIGQVAKDILKWPRPSSPPVVKLEKRVIAEYGMPSTHAMAATAISFTLLISTMDRYQYPFVLGLALVVVFSSLVCLSRLYTGMHTVLDVLGGVLITAVLISLTYPAWTLIDRLDSASPLFPVCVLVVPFFLCYNYPVSDYYSPTRADTTTILAAGAGVTIGFWINHFFQLVSEPTESLPVVQNIPPLTRDMLVLGLTKFTVGIVLILLVRQLVQNLSLQVLYSWFKVVARNKEARRRLEIEVPYKFVTYTSVGICATTFVPMLHRFLGLP", "length": 399 }, "evidence": [ { "id": "A0A8V0ZTE7", "url": "https://omabrowser.org/oma/group/A0A8V0ZTE7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0ABK0LUJ0-1", "protein_name": "Sphingosine-1-phosphate phosphatase 2", "gene_name": "Sgpp2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAELLRSLRDSELVARFQRRCGLFPGQEASGEKHVVKNYFYYYLFRFSAALGQEVFYITFLPFTHWNIDPYLSRRLVVIWVLVMYIGQVAKDILKWPRPSSPPVVKLEKRVIAEYGMPSTHAMAATAISFTLLISTMDRYQYPFILGLIMAVVFSTLVSLSRLYTGMHTVLDVLGGVLITAVLIALTYPAWTLIDSLDSASPLFPVCVIVVPFLLCYNYPVSDYYSPTRADTTTVVAAGAGVTVGFWINHFFQLVSKPTPSLPVIQNIPPITTDMLVLGLTKFMVGIMLILLVRQLVQNLSLQVLFSWFKVVTKNKEARRRLEIEVPYKFVTYTSVGICATTFVPMLHRFLGLL", "length": 354 }, "evidence": [ { "id": "A0A8V0ZTE7", "url": "https://omabrowser.org/oma/group/A0A8V0ZTE7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P23501-1", "protein_name": "Dihydrosphingosine 1-phosphate phosphatase YSR3", "gene_name": "YSR3", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MTIIQTVTELGVTEDTIKVQMAPSGGKHLLADPGNHPAEHFESQMSWLRFQTRQYLTRFTDNQSDFVHSLQKKHRTPFRDVYFKYTSLMGSHMFYVIVLPMPVWLGYRDLTRDMIYVLGYSIYLSGYLKDYWCLPRPKSPPVDRITLSEYTTKEYGAPSSHSANATAVSLLFFWRICLSDTLVWPTKLLLLSLVIFYYLTLVFGRVYCGMHGMLDLFSGAAVGAICFFIRIWVVHALRNFQIGEHLWFPLLSVAWGLFILFNHVRPIDECPCFEDSVAFIGVVSGLDCSDWLTERYGWNLVCSRYASCGSKVFLRPLVGVASVIVWKDVISKTAVYTLLIKLLRFHDDRSEKVHFHNETSEEEECLLYSGVSKVEIVGRFLIYAGIPTTVFLLCPVFFTWTNLR", "length": 404 }, "evidence": [ { "id": "A0A8V0ZTE7", "url": "https://omabrowser.org/oma/group/A0A8V0ZTE7/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q810K3-1", "protein_name": "Sphingosine-1-phosphate phosphatase 2", "gene_name": "Sgpp2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAELLRSLRDSQLVARFQRRCGLFPAREASGEEHVVKNYFYYYLFRFSAALGQEVFYITFLPFTHWNIDPNLSRRLVVIWVLVMYIGQVAKDILKWPRPSFPPVVRLEKRIIAEYGMPSTHAMAATAISFTLLISTMDRYQYPFILGLMMAVVFSTLVCLSRLYTGMHTVLDILGGVLITAVLIALTYPAWTLIDSLDSASPLFPVCVIVVPFLLCYNYPVSDYYSPTRADTTTIVAAGAGVTLGFWINHFFQLVSKPTPSLPVIQNIPPLTTDMLVLGLTKFMVGIMLILLVRQLVQKLSLQVLFSWFKVVTRNKEARRRLEIEVPYKFVTYTSVGICATTFVPMLHRFLGLL", "length": 354 }, "evidence": [ { "id": "A0A8V0ZTE7", "url": "https://omabrowser.org/oma/group/A0A8V0ZTE7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8IWX5-1", "protein_name": "Sphingosine-1-phosphate phosphatase 2", "gene_name": "SGPP2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAELLRSLQDSQLVARFQRRCGLFPAPDEGPRENGADPTERAARVPGVEHLPAANGKGGEAPANGLRRAAAPEAYVQKYVVKNYFYYYLFQFSAALGQEVFYITFLPFTHWNIDPYLSRRLIIIWVLVMYIGQVAKDVLKWPRPSSPPVVKLEKRLIAEYGMPSTHAMAATAIAFTLLISTMDRYQYPFVLGLVMAVVFSTLVCLSRLYTGMHTVLDVLGGVLITALLIVLTYPAWTFIDCLDSASPLFPVCVIVVPFFLCYNYPVSDYYSPTRADTTTILAAGAGVTIGFWINHFFQLVSKPAESLPVIQNIPPLTTYMLVLGLTKFAVGIVLILLVRQLVQNLSLQVLYSWFKVVTRNKEARRRLEIEVPYKFVTYTSVGICATTFVPMLHRFLGLP", "length": 399 }, "evidence": [ { "id": "A0A8V0ZTE7", "url": "https://omabrowser.org/oma/group/A0A8V0ZTE7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "sphingosine metabolic process", "id": "GO:0006670", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006670", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTE7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTE7" } ], "pmid": "" }, { "name": "regulation of type B pancreatic cell proliferation", "id": "GO:0061469", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061469", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTE7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTE7" } ], "pmid": "" }, { "name": "phospholipid dephosphorylation", "id": "GO:0046839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046839", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTE7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTE7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTE7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTE7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "sphingosine-1-phosphate phosphatase activity", "id": "GO:0042392", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042392", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTE7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTE7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZTE7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTE7" }, { "id": "SM00014", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00014" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Phosphatidic acid phosphatase type 2/haloperoxidase", "eco_id": "ECO_0000259", "start_pos": 118, "end_pos": 233, "start_aa": "Ser", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": 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"publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZTG3-1", "uniprot_ac": "A0A8V0ZTG3", "uniprot_id": "A0A8V0ZTG3_CHICK", "mass": { "chemical_mass": 18369.0, "monoisotopic_mass": 18369.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Death domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8V0ZTG3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTG3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTG3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTG3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTG3", "locus": {} } ], "crossref": [ { "id": "A0A8V0ZTG3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZTG3", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR000488", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000488", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011029", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011029", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PF00531", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00531", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZTG3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTG3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZTG3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTG3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGEPTPQRSPVASTEREVLLDVQRALSEEQFQTFKYLLEERLPLSRLQAATAGGGGGRGGAPHPPLTSPWVSPGGGRLLSERDLLRVAQLLGHEWQEVGVLCLGLQRCRLEQIRENNPHRTALCSFEMLREWRRREGAAATAPRLRDCLSPAQLDPEVFALLQQL", "length": 165, "header": "tr|A0A8V0ZTG3-1|A0A8V0ZTG3_CHICK Isoform 1 of Death domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0ZTG3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZTG3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTG3/entry#A0A8V0ZTG3-1", "sequence": { "sequence": "MGEPTPQRSPVASTEREVLLDVQRALSEEQFQTFKYLLEERLPLSRLQAATAGGGGGRGGAPHPPLTSPWVSPGGGRLLSERDLLRVAQLLGHEWQEVGVLCLGLQRCRLEQIRENNPHRTALCSFEMLREWRRREGAAATAPRLRDCLSPAQLDPEVFALLQQL", "length": 165, "header": "tr|A0A8V0ZTG3-1|A0A8V0ZTG3_CHICK Isoform 1 of Death domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0ZTG3-1" }, "locus": { "chromosome": "34", "start_pos": 1235649, "end_pos": 1234732, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010060052.1", "url": "https://www.ensembl.org/id/ENSGALT00010060052.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036812.1", "url": "https://www.ensembl.org/id/ENSGALP00010036812.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTG3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTG3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZTG3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTG3" }, { "id": "PS50017", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50017" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Death", "eco_id": "ECO_0000259", "start_pos": 103, "end_pos": 165, "start_aa": "Leu", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": 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"table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZTH2-1", "uniprot_ac": "A0A8V0ZTH2", "uniprot_id": "A0A8V0ZTH2_CHICK", "mass": { "chemical_mass": 30079.0, "monoisotopic_mass": 30079.0 }, "refseq": { "ac": "NP_001188374", "name": "SRR1-like protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001188374" }, "gene_names": [ { "name": "SRRD", "type": "recommended", "evidence": [ { "id": "A0A8V0ZTH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTH2" } ] }, { "name": "SRRD", "type": "synonym", "evidence": [ { "id": "NP_001188374", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001188374" } ] } ], "protein_names": [ { "name": "SRR1 domain containing", "type": "synonym", "evidence": [ { "id": "A0A8V0ZTH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTH2/entry#names_and_taxonomy" } ] }, { "name": "SRR1-like protein", "type": "synonym", "evidence": [ { "id": "NP_001188374", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001188374" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: BU354861.1, BU318093.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992415, SAMEA103992432 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000260.1. On Dec 3, 2021 this sequence version replaced NP_001188374.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001188374", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001188374" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTH2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTH2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SRRD", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTH2", "locus": { "chromosome": "15", "start_pos": 7166662, "end_pos": 7164843, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010023578", "url": "https://www.ensembl.org/id/ENSGALG00010023578" } ] } } ], "crossref": [ { "id": "A0A8V0ZTH2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZTH2", "database": "AlphaFoldDB", "categories": [] }, { "id": "416908", "url": "https://www.ncbi.nlm.nih.gov/gene/416908", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR012942", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012942", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040044", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040044", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416908", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416908", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VVTRKKW", "url": "https://omabrowser.org/oma/group/VVTRKKW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZTH2", "url": "https://www.orthodb.org/?gene=A0A8V0ZTH2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR28626", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28626", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR28626:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28626:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07985", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07985", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001188374", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001188374", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZTH2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTH2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZTH2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTH2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAAGCWRAASGRRRRKRGEKEEESGVAVLRRLRDARDELLSSGFWAASAGAVREPLGSGRAWRCVCYGLGRFAACPAARLQLAFLLLLLEMLEVPPRHCFLFDPAFSELELAALEALGLHLLPENEEGKHSTNGSPTLFYMVHCGKALYNNLLWRNWSVGALSNMVIIGNSFKGIEERLLTRILERDYSYIAKILKGVEEVALPAHPRYSDTFNDTSIHWFPAHKLERLSAEVWQFLEEPTYEDCDDLEIIRKGEEGSQHGPAPAQP", "length": 268, "header": "tr|A0A8V0ZTH2-1|A0A8V0ZTH2_CHICK Isoform 1 of SRR1 domain containing OS=Gallus gallus OX=9031 GN=SRRD PE=3 SV=1 CANONICAL=A0A8V0ZTH2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZTH2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTH2/entry#A0A8V0ZTH2-1", "sequence": { "sequence": "MAAAGCWRAASGRRRRKRGEKEEESGVAVLRRLRDARDELLSSGFWAASAGAVREPLGSGRAWRCVCYGLGRFAACPAARLQLAFLLLLLEMLEVPPRHCFLFDPAFSELELAALEALGLHLLPENEEGKHSTNGSPTLFYMVHCGKALYNNLLWRNWSVGALSNMVIIGNSFKGIEERLLTRILERDYSYIAKILKGVEEVALPAHPRYSDTFNDTSIHWFPAHKLERLSAEVWQFLEEPTYEDCDDLEIIRKGEEGSQHGPAPAQP", "length": 268, "header": "tr|A0A8V0ZTH2-1|A0A8V0ZTH2_CHICK Isoform 1 of SRR1 domain containing OS=Gallus gallus OX=9031 GN=SRRD PE=3 SV=1 CANONICAL=A0A8V0ZTH2-1" }, "locus": { "chromosome": "15", "start_pos": 7166516, "end_pos": 7164915, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010057388.1", "url": "https://www.ensembl.org/id/ENSGALT00010057388.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034875.1", "url": "https://www.ensembl.org/id/ENSGALP00010034875.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:416908", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416908", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q9VEB5-1", "protein_name": "SRR1-like protein", "gene_name": "", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSNSGEDFQVVTRKKWMARKCLRRRDRHKSESDYLIDCPDVNVEKFQPRLENLCTEMCQSDYFLVAMEALQQQLEGIRKPLERIVCLGLGPFSRTYHALHQAAFVIGLHRHHKIREALYFDPVFRDSEKELIRLFDGCIMSKDCAGKHEATVPTLYYLPHCPYALMHNILWSNWKRETLPNVFLISNSFEMLTMTPRNQDDHITRIVEHCTETPLEDDYEHHNVFNDLSLHTFPQESLPGSNDEAFWTRCAPLKVNEDELITETETSLAALKLESE", "length": 276 }, "evidence": [ { "id": "A0A8V0ZTH2", "url": "https://omabrowser.org/oma/group/A0A8V0ZTH2/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTH2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTH2" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTH2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTH2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "regulation of circadian rhythm", "id": "GO:0042752", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042752", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTH2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTH2" } ], "pmid": "" }, { "name": "regulation of heme biosynthetic process", "id": "GO:0070453", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070453", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTH2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTH2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 134, "end_pos": 136, "annotation": "n_glycosylation_sequon" }, { "start_pos": 157, "end_pos": 159, "annotation": "n_glycosylation_sequon" }, { "start_pos": 215, "end_pos": 217, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], 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"total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZTN0-1", "uniprot_ac": "A0A8V0ZTN0", "uniprot_id": "A0A8V0ZTN0_CHICK", "mass": { "chemical_mass": 164400.0, "monoisotopic_mass": 164400.0 }, "refseq": {}, "gene_names": [ { "name": "LRRC7", "type": "recommended", "evidence": [ { "id": "A0A8V0ZTN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTN0" } ] } ], "protein_names": [ { "name": "Leucine-rich repeat-containing protein 7", "type": "recommended", "evidence": [ { "id": "A0A8V0ZTN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTN0/entry#names_and_taxonomy" } ] }, { "name": "Densin-180", "type": "synonym", "evidence": [ { "id": "A0A8V0ZTN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTN0/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Required for normal synaptic spine architecture and function. Necessary for DISC1 and GRM5 localization to postsynaptic density complexes and for both N-methyl D-aspartate receptor-dependent and metabotropic glutamate receptor-dependent long term depression.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTN0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTN0#function" }, { "database": "UniProtKB", "id": "ARBA00059232", "url": "https://www.uniprot.org/uniprotkb/ARBA00059232#function" }, { "database": "UniProtKB", "id": "A0A8V1A173", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A173#function" }, { "database": "UniProtKB", "id": "A0A8V0ZX48", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZX48#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTN0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTN0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LRRC7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTN0", "locus": { "chromosome": "8", "start_pos": 28669724, "end_pos": 28577849, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010023606", "url": "https://www.ensembl.org/id/ENSGALG00010023606" } ] } } ], "crossref": [ { "id": "cd06749", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06749", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "424711", "url": "https://www.ncbi.nlm.nih.gov/gene/424711", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001478", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001478", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003591", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003591", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036034", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036034", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050614", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050614", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055414", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055414", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZTN0", "url": "https://www.orthodb.org/?gene=A0A8V0ZTN0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZX48", "url": "https://www.orthodb.org/?gene=A0A8V0ZX48", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A173", "url": "https://www.orthodb.org/?gene=A0A8V1A173", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23119", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23119", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23119:SF48", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23119:SF48", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00595", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00595", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13855", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13855", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23598", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23598", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-438066", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-438066", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5673001", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5673001", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-6798695", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZTN0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTN0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZTN0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTN0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZX48", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZX48", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZX48-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZX48-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A173", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A173", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A173-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A173-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPCLEMTTKRKIIGRLVPCRCFRGEEEIVSVLDYSHCGLQQVPKEVFNFERTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDLSSLPTTIASLVNLRELDISKNGIQDFPENIKCCKCLTIIEASVNPVSKLPDGFTQLLNLTQLYLNDAFLEFLPANFGRLVKLRILELRENHLKTLPKSMHKLTQLERLDLGNNEFSELPEVLEQIQNLKELWMDNNSLQILPGSIGKLKQLVYLDMSKNRIETVDLDISGCEGLEDLLLSSNMLQQLPDSIGLLKRLTTLKVDDNQLTILPNAIGNLSLLEEFDCSCNELESLPSTIGYLHNLRTLAVDENFLPELPREIGSCKNVTVMSLRSNKLEFLPDEIGQMQKLRVLNLSDNRLKNLPFTFTKLKELAALWLSDNQSKALIPLQTEAHPETKQRVLTNYMFPQQPRSDEDFQSDSDSFNPTLWEEQRQQRMTVAFEFEEKKEEEENPGKVKVEINLKRYPTPYPEDLKNMVKSVQNLVGKTSHGVRPENSAPSANTEQTVKEKYEHKWPMAPKEISVEDAFGHPASEMRIGELRPSLPETPLYPPKLVLLGKDKKESTDESEADKIHCLNNSVSSGTYSDYSPSQASSGSSNAHVKMGSLQTTAKEAVNNSLWGNSRLVQSFPQPLETKPLLSQRESVPAGNVPPRTDRRPLSDTFTDSWNDSSHYDNTGFVAEESAVENPSANPLLSTKSRSTSAHGRRPLIRQDRIVGIPLELEQPTLRNTHESEVPPPNPWQNWTRTPSPFEDRTAFPSKLENTPTTSPLPERKDHVKESPEITSTFAPRIAWEYHDSNANRSLTNVFSHIHCRPDPSKSVISISKSTERLSPMMRDLKTNKFKKSQSIDEIDIGTYKVYNIPLENYASGNDTVGAHERVDKLLGPEHSMLSMSRSQSVPMLDDELLTYGSVKVQPQQKSSVTKKVYQFDQSFNPQGAVEVTAEKRLPPPFQLNPEYIAPQSKNLPQELVSPRVYRGYPPVEHMFSFSQPSVNEDAISTPFTSQGSRPGFLRRADSLASSTEMSMFRRVSEPHELPPGDRYGRPPYRGAMERQGSISVSESQFLKRNGRYEDEHPSYQEVKAQTGSFPVKNLTQRRPLSARSYSTESYGTSQTRPVSARPTMAALLEKIPSDYNLGNYGDKPSDNSDIKTRPTPVKGNESCAKMPADWRQQLLRHIEARRLDRTAAYKHNTVSLGMLHSGGFSAMHAGRSMTLNLQTKSKFENQMLQELPLPKTPSQQSSILDNGQDEGPGSGQWNPYPLGRRDVPPDTVTKKAGSHIQTLMGSQSLQHRSREQQYEGNMNKVTIQQYQPPLPIQIPSSQSSRAPQTGRCLIQTKGQRSTDAYQEQFCVRIEKNPGLGFSISGGISGQGNPFKPSDKGIFVTRVQPDGPASSLLQPGDKILQANGHSFVHMEHEKAVLLLKSFQNTVDLVIQRELTV", "length": 1461, "header": "tr|A0A8V0ZTN0-1|A0A8V0ZTN0_CHICK Isoform 1 of Leucine-rich repeat-containing protein 7 OS=Gallus gallus OX=9031 GN=LRRC7 PE=3 SV=1 CANONICAL=A0A8V0ZTN0-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZTN0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTN0/entry#A0A8V0ZTN0-1", "sequence": { "sequence": "MPCLEMTTKRKIIGRLVPCRCFRGEEEIVSVLDYSHCGLQQVPKEVFNFERTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDLSSLPTTIASLVNLRELDISKNGIQDFPENIKCCKCLTIIEASVNPVSKLPDGFTQLLNLTQLYLNDAFLEFLPANFGRLVKLRILELRENHLKTLPKSMHKLTQLERLDLGNNEFSELPEVLEQIQNLKELWMDNNSLQILPGSIGKLKQLVYLDMSKNRIETVDLDISGCEGLEDLLLSSNMLQQLPDSIGLLKRLTTLKVDDNQLTILPNAIGNLSLLEEFDCSCNELESLPSTIGYLHNLRTLAVDENFLPELPREIGSCKNVTVMSLRSNKLEFLPDEIGQMQKLRVLNLSDNRLKNLPFTFTKLKELAALWLSDNQSKALIPLQTEAHPETKQRVLTNYMFPQQPRSDEDFQSDSDSFNPTLWEEQRQQRMTVAFEFEEKKEEEENPGKVKVEINLKRYPTPYPEDLKNMVKSVQNLVGKTSHGVRPENSAPSANTEQTVKEKYEHKWPMAPKEISVEDAFGHPASEMRIGELRPSLPETPLYPPKLVLLGKDKKESTDESEADKIHCLNNSVSSGTYSDYSPSQASSGSSNAHVKMGSLQTTAKEAVNNSLWGNSRLVQSFPQPLETKPLLSQRESVPAGNVPPRTDRRPLSDTFTDSWNDSSHYDNTGFVAEESAVENPSANPLLSTKSRSTSAHGRRPLIRQDRIVGIPLELEQPTLRNTHESEVPPPNPWQNWTRTPSPFEDRTAFPSKLENTPTTSPLPERKDHVKESPEITSTFAPRIAWEYHDSNANRSLTNVFSHIHCRPDPSKSVISISKSTERLSPMMRDLKTNKFKKSQSIDEIDIGTYKVYNIPLENYASGNDTVGAHERVDKLLGPEHSMLSMSRSQSVPMLDDELLTYGSVKVQPQQKSSVTKKVYQFDQSFNPQGAVEVTAEKRLPPPFQLNPEYIAPQSKNLPQELVSPRVYRGYPPVEHMFSFSQPSVNEDAISTPFTSQGSRPGFLRRADSLASSTEMSMFRRVSEPHELPPGDRYGRPPYRGAMERQGSISVSESQFLKRNGRYEDEHPSYQEVKAQTGSFPVKNLTQRRPLSARSYSTESYGTSQTRPVSARPTMAALLEKIPSDYNLGNYGDKPSDNSDIKTRPTPVKGNESCAKMPADWRQQLLRHIEARRLDRTAAYKHNTVSLGMLHSGGFSAMHAGRSMTLNLQTKSKFENQMLQELPLPKTPSQQSSILDNGQDEGPGSGQWNPYPLGRRDVPPDTVTKKAGSHIQTLMGSQSLQHRSREQQYEGNMNKVTIQQYQPPLPIQIPSSQSSRAPQTGRCLIQTKGQRSTDAYQEQFCVRIEKNPGLGFSISGGISGQGNPFKPSDKGIFVTRVQPDGPASSLLQPGDKILQANGHSFVHMEHEKAVLLLKSFQNTVDLVIQRELTV", "length": 1461, "header": "tr|A0A8V0ZTN0-1|A0A8V0ZTN0_CHICK Isoform 1 of Leucine-rich repeat-containing protein 7 OS=Gallus gallus OX=9031 GN=LRRC7 PE=3 SV=1 CANONICAL=A0A8V0ZTN0-1" }, "locus": { "chromosome": "8", "start_pos": 28668121, "end_pos": 28584188, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010057483.1", "url": "https://www.ensembl.org/id/ENSGALT00010057483.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034931.1", "url": "https://www.ensembl.org/id/ENSGALP00010034931.1" } ] } }, { "isoform_ac": "A0A8V0ZX48-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTN0/entry#A0A8V0ZX48-1", "sequence": { "sequence": "MPCLEMTTKRKIIGRLVPCRCFRGEEEIVSVLDYSHCGLQQVPKEVFNFERTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDLSSLPTTIASLVNLRELDISKNGIQDFPENIKCCKCLTIIEASVNPVSKLPDGFTQLLNLTQLYLNDAFLEFLPANFGRLVKLRILELRENHLKTLPKSMHKLTQLERLDLGNNEFSELPEVLEQIQNLKELWMDNNSLQILPGSIGKLKQLVYLDMSKNRIETVDLDISGCEGLEDLLLSSNMLQQLPDSIGLLKRLTTLKVDDNQLTILPNAIGNLSLLEEFDCSCNELESLPSTIGYLHNLRTLAVDENFLPELPREIGSCKNVTVMSLRSNKLEFLPDEIGQMQKLRVLNLSDNRLKNLPFTFTKLKELAALWLSDNQSKALIPLQTEAHPETKQRVLTNYMFPQQPRSDEDFQSDSDSFNPTLWEEQRQQRMTVAFEFEEKKEEEENPGKVKVEINLKRYPTPYPEDLKNMVKSVQNLVGKTSHGVRPENSAPSANTEQTVKEKYEHKWPMAPKEISVEVQEFHKSHLSDTDNTHKSTLDRKEKEEHTKSSEDAFGHPASEMRIGELRPSLPETPLYPPKLVLLGKDKKESTDESEADKIHCLNNSVSSGTYSDYSPSQASSGSSNAHVKMGSLQTTAKEAVNNSLWGNRLVQSFPQPLETKPLLSQRESVPAGNVPPRTDRRPLSDTFTDSWNDSSHYDNTGFVAEESAVENPSANPLLSTKSRSTSAHGRRPLIRQDRIVGIPLELEQPTLRNTHESEVPPPNPWQNWTRTPSPFEDRTAFPSKLENTPTTSPLPERKDHVKESPEITSTFAPRIAWEYHDSNANRSLTNVFSHIHCRPDPSKSVISISKSTERLSPMMRDLKTNKFKKSQSIDEIDIGTYKVYNIPLENYASGNDTVGAHERVDKLLGPEHSMLSMSRSQSVPMLDDELLTYGSVKVQPQQKSSVTKKVYQFDQSFNPQGAVEVTAEKRLPPPFQLNPEYIAPQSKNLPQELVSPRVYRGYPPVEHMFSFSQPSVNEDAISTPFTSQGSRPGFLRRADSLASSTEMSMFRRVSEPHELPPGDRYGRPPYRGAMERQGSISVSESQFLKRNGRYEDEHPSYQEVKAQTGSFPVKNLTQRRPLSARSYSTESYGTSQTRPVSARPTMAALLEKIPSDYNLGNYGDKPSDNSDIKTRPTPVKGNESCAKMPADWRQQLLRHIEARRLDRTPSQQSSILDNGQDEGPGSGQWNPYPLGRRDVPPDTVTKKAGSHIQTLMGSQSLQHRSREQQYEGNMNKVTIQQYQPPLPIQIPSSQSSRAPQTGRCLIQTKGQRSTDAYQEQFCVRIEKNPGLGFSISGGISGQGNPFKPSDKGIFVTRVQPDGPASSLLQPGDKILQANGHSFVHMEHEKAVLLLKSFQNTVDLVIQRELTV", "length": 1443, "header": "tr|A0A8V0ZX48-1|A0A8V0ZTN0_CHICK Computationally mapped isoform of Leucine-rich repeat-containing protein 7 OS=Gallus gallus OX=9031 GN=LRRC7 PE=3 SV=1 CANONICAL=A0A8V0ZTN0-1" }, "locus": { "chromosome": "8", "start_pos": 28668121, "end_pos": 28584188, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010057501.1", "url": "https://www.ensembl.org/id/ENSGALT00010057501.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034939.1", "url": "https://www.ensembl.org/id/ENSGALP00010034939.1" } ] } }, { "isoform_ac": "A0A8V1A173-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTN0/entry#A0A8V1A173-1", "sequence": { "sequence": 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"AAPAPHSLGRTQNGAKVPPSYPFPREAEGRQNSASGCLRAGGGAVAPLTGGIILEYVEGGELKTRSIDLLDLSPHTDVIALVEEIQKEEPLITASCKEHVIRLVQRLQEKLGEKEDHKFYLFKVLRAHILPLTNVAFNKSGSCFITGSYDRTCKVWDTASGEELHTLEGHKNVVYAIAFNNPYGDKIATGSFDKTCKLWSTETGKCYHTFRGHTAEIVCLSFNLQSTLVATGSMDTTAKLWDIEKGEVAFTLRGHSAEIVALSFNTTGDRIITGSFDCTVGVWDVVTGRMLHVLIGHRGEISSAQFNWDCSLIVTGSMDKTCMLWNATTGAHIATLTGHSDEIMDVCFDYAGQRIATASADGSGRVYNAETKKCIAKLEGHGGEISKICFNPKGNRILTASSDKTARLWDAATGHCLQILEGHTDEIFSCAFNYKGNIIITGSKDNTCRVWH", "length": 452, "header": "tr|A0A8V0ZTP2-1|A0A8V0ZTP2_CHICK Isoform 1 of Dynein assembly factor with WD repeat domains 1 OS=Gallus gallus OX=9031 GN=DAW1 PE=3 SV=1 CANONICAL=A0A8V0ZTP2-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2UE23-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTP2/entry#A0A3Q2UE23-1", "sequence": { "sequence": "MGPRRLLLRYFPPGIILEYVEGGELKTRSIDLLDLSPHTDVIALVEEIQKEEPLITASCKEHVIRLVQRLQEKLGEKEDHKFYLFKVLRAHILPLTNVAFNKSGSCFITGSYDRTCKVWDTASGEELHTLEGHKNVVYAIAFNNPYGDKIATGSFDKTCKLWSTETGKCYHTFRGHTAEIGHSAEIVALSFNTTGDRIITGSFDCTVGVWDVVTGRMLHVLIGHRGEISSAQFNWDCSLIVTGSMDKTCMLWNATTGAHIATLTGHSDEIMDVCFDYAGQRIATASADGSGRVYNAETKKCIAKLEGHGGEISKICFNPKGNRILTASSDKTARLWDAATGHCLQILEGHTDEIFSCAFNYKGNIIITGSKDNTCRVWH", "length": 379, "header": "tr|A0A3Q2UE23-1|A0A3Q2UE23_CHICK Computationally mapped isoform of Dynein assembly factor with WD repeat domains 1 OS=Gallus gallus OX=9031 GN=DAW1 PE=3 SV=1 CANONICAL=A0A8V0ZTP2-1" }, "locus": { "chromosome": "9", "start_pos": 9233919, "end_pos": 9217525, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056444.1", "url": "https://www.ensembl.org/id/ENSGALT00010056444.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034187.1", "url": "https://www.ensembl.org/id/ENSGALP00010034187.1" } ] } }, { "isoform_ac": "A0A8V0ZRP9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTP2/entry#A0A8V0ZRP9-1", "sequence": { "sequence": "MAAGGACTQALFGRCRGNEPQAAEMGPRRLLLRYFPPGIILEYVEGGELKTRSIDLLDLSPHTDVIALVEEIQKEEPLITASCKEHVIRLVQRLQEKLGEKEDHKFYLFKVLRAHILPLTNVAFNKSGSCFITGSYDRTCKVWDTASGEELHTLEGHKNVVYAIAFNNPYGDKIATGSFDKTCKLWSTETGKCYHTFRGHTAEIVCLSFNLQSTLVATGSMDTTAKLWDIEKGEVAFTLRGHSAEIVALSFNTTGDRIITGSFDCTVGVWDVVTGRMLHVLIGHRGEISSAQFNWDCSLIVTGSMDKTCMLWNATTGAHIATLTGHSDEIMDVCFDYAGQRIATASADGSGRVYNAETKKCIAKLEGHGGEISKICFNPKGNRILTASSDKTARLWDAATGHCLQILEGHTDEIFSCAFNYKGNIIITGSKDNTCRVWH", "length": 439, "header": "tr|A0A8V0ZRP9-1|A0A8V0ZRP9_CHICK Computationally mapped isoform of Dynein assembly factor with WD repeat domains 1 OS=Gallus gallus OX=9031 GN=DAW1 PE=3 SV=1 CANONICAL=A0A8V0ZTP2-1" }, "locus": { "chromosome": "9", "start_pos": 9233919, "end_pos": 9217453, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056456.1", "url": "https://www.ensembl.org/id/ENSGALT00010056456.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034199.1", "url": "https://www.ensembl.org/id/ENSGALP00010034199.1" } ] } }, { "isoform_ac": "A0A8V0ZTP2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTP2/entry#A0A8V0ZTP2-1", "sequence": { "sequence": "AAPAPHSLGRTQNGAKVPPSYPFPREAEGRQNSASGCLRAGGGAVAPLTGGIILEYVEGGELKTRSIDLLDLSPHTDVIALVEEIQKEEPLITASCKEHVIRLVQRLQEKLGEKEDHKFYLFKVLRAHILPLTNVAFNKSGSCFITGSYDRTCKVWDTASGEELHTLEGHKNVVYAIAFNNPYGDKIATGSFDKTCKLWSTETGKCYHTFRGHTAEIVCLSFNLQSTLVATGSMDTTAKLWDIEKGEVAFTLRGHSAEIVALSFNTTGDRIITGSFDCTVGVWDVVTGRMLHVLIGHRGEISSAQFNWDCSLIVTGSMDKTCMLWNATTGAHIATLTGHSDEIMDVCFDYAGQRIATASADGSGRVYNAETKKCIAKLEGHGGEISKICFNPKGNRILTASSDKTARLWDAATGHCLQILEGHTDEIFSCAFNYKGNIIITGSKDNTCRVWH", "length": 452, "header": "tr|A0A8V0ZTP2-1|A0A8V0ZTP2_CHICK Isoform 1 of Dynein assembly factor with WD repeat domains 1 OS=Gallus gallus OX=9031 GN=DAW1 PE=3 SV=1 CANONICAL=A0A8V0ZTP2-1" }, "locus": { "chromosome": "9", "start_pos": 9233919, "end_pos": 9217716, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056447.1", "url": "https://www.ensembl.org/id/ENSGALT00010056447.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034190.1", "url": "https://www.ensembl.org/id/ENSGALP00010034190.1" } ] } }, { "isoform_ac": "A0A8V0ZUQ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTP2/entry#A0A8V0ZUQ5-1", "sequence": { "sequence": "MGPRRLLLRYFPPGIILEYVEGGELKTRSIDLLDLSPHTDVIALVEEIQKEEPLITASCKEHVIRLVQRLQEKLGEKEDHKFYLFKVLRAHILPLTNVAFNKSGSCFITGSYDRTCKVWDTASGEELHTLEGHKNVVYAIAFNNPYGMLHVLIGHRGEISSAQFNWDCSLIVTGSMDKTCMLWNATTGAHIATLTGHSDEIMDVCFDYAGQRIATASADGSGRVYNAETKKCIAKLEGHGGEISKICFNPKGNRILTASSDKTARLWDAATGHCLQILEGHTDEIFSCAFNYKGNIIITGSKDNTCRVWH", "length": 310, "header": "tr|A0A8V0ZUQ5-1|A0A8V0ZTP2_CHICK Computationally mapped isoform of Dynein assembly factor with WD repeat domains 1 OS=Gallus gallus OX=9031 GN=DAW1 PE=3 SV=1 CANONICAL=A0A8V0ZTP2-1" }, "locus": { "chromosome": "9", "start_pos": 9233919, "end_pos": 9217525, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056451.1", "url": "https://www.ensembl.org/id/ENSGALT00010056451.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034194.1", "url": "https://www.ensembl.org/id/ENSGALP00010034194.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:424790", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424790", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "heart development", "id": "GO:0007507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007507", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTP2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTP2" } ], "pmid": "" }, { "name": "determination of left/right symmetry", "id": "GO:0007368", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007368", "evidence": [ { "database": 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"database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45817:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45817:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01186", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01186", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "24544", "url": "https://www.rhea-db.org/rhea/24544", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZTP4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTP4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZTP4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTP4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "RQPSSSSAASAAASSFAYAAAGHAAYPQPPFEQHEAAPRAYDEAYTYYRGGGGGGGGVAVAAAGAGALYPFQPRGRYEDYGEEQSPYRAQGFYPERPYAAPQDGLDRRYSHSLYHDAGAVPEHGAVISNDNLQPPVGSQPASGTAYGNQYQPYEAQPPFRALEPYGAVRPDVFVPARSPEVPQAVPDGQARLSVGSVYRPSHGGRGLPDLVPDPNYVQASTYVQRAHLYSLRCAAEEKCLASTAYTPEATDYDVRVLLRFPQRVKNQGTADFLPSRPRHSWEWHSCHQHYHSMDEFSHYDLLDATTGRKVAEGHKASFCLEDTTCDFGNLKRYACTSHTQGLSPGCYDTYNADIDCQWIDITDVQPGNYVLKVQVNPKYIVLESDFTNNVVRCNIHYTGRYVATTNCKISQS", "length": 412, "header": "tr|A0A8V0ZTP4-1|A0A8V0ZTP4_CHICK Isoform 1 of protein-lysine 6-oxidase OS=Gallus gallus OX=9031 GN=LOXL1 PE=1 SV=1 CANONICAL=A0A8V0ZTP4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZTP4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTP4/entry#A0A8V0ZTP4-1", "sequence": { "sequence": "RQPSSSSAASAAASSFAYAAAGHAAYPQPPFEQHEAAPRAYDEAYTYYRGGGGGGGGVAVAAAGAGALYPFQPRGRYEDYGEEQSPYRAQGFYPERPYAAPQDGLDRRYSHSLYHDAGAVPEHGAVISNDNLQPPVGSQPASGTAYGNQYQPYEAQPPFRALEPYGAVRPDVFVPARSPEVPQAVPDGQARLSVGSVYRPSHGGRGLPDLVPDPNYVQASTYVQRAHLYSLRCAAEEKCLASTAYTPEATDYDVRVLLRFPQRVKNQGTADFLPSRPRHSWEWHSCHQHYHSMDEFSHYDLLDATTGRKVAEGHKASFCLEDTTCDFGNLKRYACTSHTQGLSPGCYDTYNADIDCQWIDITDVQPGNYVLKVQVNPKYIVLESDFTNNVVRCNIHYTGRYVATTNCKISQS", "length": 412, "header": "tr|A0A8V0ZTP4-1|A0A8V0ZTP4_CHICK Isoform 1 of protein-lysine 6-oxidase OS=Gallus gallus OX=9031 GN=LOXL1 PE=1 SV=1 CANONICAL=A0A8V0ZTP4-1" }, "locus": { "chromosome": "10", "start_pos": 2366440, "end_pos": 2358170, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010057520.1", "url": "https://www.ensembl.org/id/ENSGALT00010057520.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034948.1", "url": "https://www.ensembl.org/id/ENSGALP00010034948.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTP4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTP4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "copper ion binding", "id": "GO:0005507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005507", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTP4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTP4" } ], "pmid": "" }, { "name": "protein-lysine 6-oxidase activity", "id": "GO:0004720", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004720", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTP4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTP4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "24544", "name": "", "equation": "L-lysyl-[protein] + O2 + H2O = (S)-2-amino-6-oxohexanoyl-[protein] + H2O2 + NH4(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZCA5-1", "A0A8V0XH29-1", "A0A8V0XAJ0-1", "A0A8V0ZTP4-1", "E1C3U7-1", "Q05063-1", "A0A8V0Z7G4-1" ], "evidence": [ { "id": "24544", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/24544" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0XAJ0", "gene_name": "LOX", "activity": [ { "ec_number": "1.4.3.13", "activity": "L-lysyl-[protein] + O2 + H2O = (S)-2-amino-6-oxohexanoyl-[protein] + H2O2 + NH4(+).", "evidence": [ { "id": "A0A8V0XAJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XAJ0" } ] }, { "ec_number": "1.4.3.13", "activity": "", "evidence": [ { "id": "A0A8V0XAJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XAJ0" } ] } ] }, { "uniprot_ac": "A0A8V0XH29", "gene_name": "LOXL3", "activity": [ { "ec_number": "1.4.3.13", "activity": "L-lysyl-[protein] + O2 + H2O = (S)-2-amino-6-oxohexanoyl-[protein] + H2O2 + NH4(+).", "evidence": [ { "id": "A0A8V0XH29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XH29" } ] }, { "ec_number": "1.4.3.13", "activity": "", "evidence": [ { "id": "A0A8V0XH29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XH29" } ] } ] }, { "uniprot_ac": "A0A8V0Z7G4", "gene_name": "LOXL4", "activity": [ { "ec_number": "1.4.3.13", "activity": "L-lysyl-[protein] + O2 + H2O = (S)-2-amino-6-oxohexanoyl-[protein] + H2O2 + NH4(+).", "evidence": [ { "id": "A0A8V0Z7G4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7G4" } ] }, { "ec_number": "1.4.3.13", "activity": "", "evidence": [ { "id": "A0A8V0Z7G4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7G4" } ] } ] }, { "uniprot_ac": "A0A8V0ZCA5", "gene_name": "LOXL2", "activity": [ { "ec_number": "1.4.3.13", "activity": "L-lysyl-[protein] + O2 + H2O = (S)-2-amino-6-oxohexanoyl-[protein] + H2O2 + NH4(+).", "evidence": [ { "id": "A0A8V0ZCA5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCA5" } ] }, { "ec_number": "1.4.3.13", "activity": "", "evidence": [ { "id": "A0A8V0ZCA5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCA5" } ] } ] }, { "uniprot_ac": "A0A8V0ZTP4", "gene_name": "LOXL1", "activity": [ { "ec_number": "1.4.3.13", "activity": "L-lysyl-[protein] + O2 + H2O = (S)-2-amino-6-oxohexanoyl-[protein] + H2O2 + NH4(+).", "evidence": [ { "id": "A0A8V0ZTP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTP4" } ] }, { "ec_number": "1.4.3.13", "activity": "", "evidence": [ { "id": "A0A8V0ZTP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTP4" } ] } ] }, { "uniprot_ac": "E1C3U7", "gene_name": "LOXL2", "activity": [ { "ec_number": "1.4.3.13", "activity": "L-lysyl-[protein] + O2 + H2O = (S)-2-amino-6-oxohexanoyl-[protein] + H2O2 + NH4(+).", "evidence": [ { "id": "E1C3U7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C3U7" } ] }, { "ec_number": "1.4.3.13", "activity": "", "evidence": [ { "id": "E1C3U7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C3U7" } ] } ] }, { "uniprot_ac": "Q05063", "gene_name": "LOX", "activity": [ { "ec_number": "1.4.3.13", "activity": "L-lysyl-[protein] + O2 + H2O = (S)-2-amino-6-oxohexanoyl-[protein] + H2O2 + NH4(+).", "evidence": [ { "id": "Q05063", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q05063" } ] }, { "ec_number": "1.4.3.13", "activity": "", "evidence": [ { "id": "Q05063", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q05063" } ] } ] } ], "biomarkers": 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"n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZTQ6-1", "uniprot_ac": "A0A8V0ZTQ6", "uniprot_id": "A0A8V0ZTQ6_CHICK", "mass": { "chemical_mass": 183300.0, "monoisotopic_mass": 183300.0 }, "refseq": {}, "gene_names": [ { "name": "SPHKAP", 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"MAGRPPPSNFESPLMQEVPEHQGNSTDSSGSSLGSTVTACKKILCSNSLLESTDYWLQNQRTPCQIGFLEDKSESNCASVCFVNLDANRDDCSNEQVKQKLISVSPNLPKLIGSMNVQPPKENEIVLLSGLTSGNLQADYEVPQCPWQADVCLVQCARGDRKNSASCIIFEINKFLIGLELVQERQLQIEAHVSKPEDDTNCSVSSIEEDFLTASEHLEEENEADEYKTAHEKISVSEASSDVRKNKGKGFESLHYRKARLPLILEGNCVNEDNTASKVSESVHVVAEDGISQPEDKPEQEILCQEELVGRDTSSLSTEDLTNNVENSCSVNVLDVSLTKMAKEELGPYGSTAKPNSKAEVEDCAGVRKSDPPLQNEQAATGQYATNLAESVLQDAFIRLSQSQPTFSEEAAVSISVGSSCKSKDASASRSWNELPKIVIVQSPDSSENVPDWPGSAFPNLCHWTETESSEVSDYFEEDHSNGRSQSALEMALACAATVIGTISSPQAAEKFRRDQEATDSKSETVDNEDLHADSSQLLEDCTSTDYSFPSALCGMTQVASAVAVCGLGETKEEKYPTTSSGLLSAAQTSAAITLHCSIAVGSSMEKLNDSIAEALLKEASIILTKPNTYKNVGHFMESINGRIIETAARPRIPHSDEVIRDELAQNLSNIILRHSIEEVRKKRELQSCSENSSSTQDIFMETANELLFNVIYFTCKKMNDIRQVEECSPLFSEGLKGKKVTRVEGWPTQATACETSHRPLDHSAIKPFGTSYSASTDSENGISTKKINMRDVNSNENATVNSELTSRVIGHNALVAKTSPKKRYLKRTTRDCYKSPHQNNIQKKRDYRSFSDRESTFANNECRHGVQEQLSSSAVVNAENQAKHKCDAVLSDEVQVSLSLLGNHVLLPSQPVLQVKNSRDKYCITDFAEELAETVVSMATEIAAICLENSNGKQPWFCAWKRGNEYLVTQSISCRTMKRKKETHANGSVVRKHRAPRLSEIKRKTDEHPELKERLMNRVVDESINLEDTPDSVNIFANEVAAKIMNLTELSMVDSIWQGPNHPRNRLHCERWSRAKASSCESIPEEDMDSKASANTLGLMNALGQPVSQTSSVSKQSSCESITDEFSRFMVNQMENEGRGFDLLLDYYAGKNANNILTSALQQVAKKNGHLNVRPSCPSKQSSTESITEEFYRYMLKEIEKENKDNASSPRNSKDWCGSLLPPSLRSPFCFRQSSVPDGRSSGSRLTVNIPVKANSLDGFAQHHQDSLSVQPVSTVASSGLCKSDSCLYQRCKTDQITDMLIHETWASSIESLMRKNKIITDEAEVAEVDHFHSDSPPHVQQYANRLAANIVESGKNLIVVQQDAFDSASQEHMLESKHPQSATQIQVEPKRSGINLDEHMKNPECLPAGQHREVPLIQIETDQRDESDKDSESLTLHELSEKEHQGKEKPPEAYAGKHMVSSTLLNSKSSQSKPDAEITGETKAAEEFPTHLSSSEESTGSWSQLANDEDNPDDTSSYLQLSERSLSDLVEEKVFLKEQTDNTEESTSGLSVGTANYQKELLVINFDLEPECPNAELRATLQWIAASELGIPTIYFKKSQENRIEKFLDVVQLVQRKSWKVGDIFHAVVQYCKLSEERKEKTPSLFDWLLELG", "length": 1655, "header": "tr|A0A8V0ZTQ6-1|A0A8V0ZTQ6_CHICK Isoform 1 of SPHK1 interactor, AKAP domain containing OS=Gallus gallus OX=9031 GN=SPHKAP PE=3 SV=1 CANONICAL=A0A8V0ZTQ6-1" }, "locus": { "chromosome": "9", "start_pos": 9304595, "end_pos": 9239389, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056464.1", "url": "https://www.ensembl.org/id/ENSGALT00010056464.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034207.1", "url": "https://www.ensembl.org/id/ENSGALP00010034207.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTQ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTQ6" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTQ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTQ6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein kinase A binding", "id": "GO:0051018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051018", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTQ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTQ6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1047, "end_pos": 1049, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1207, "end_pos": 1209, "annotation": "n_glycosylation_sequon" }, { "start_pos": 201, "end_pos": 203, "annotation": "n_glycosylation_sequon" }, { "start_pos": 24, "end_pos": 26, "annotation": "n_glycosylation_sequon" }, { "start_pos": 609, "end_pos": 611, "annotation": "n_glycosylation_sequon" }, { "start_pos": 667, "end_pos": 669, "annotation": "n_glycosylation_sequon" }, { "start_pos": 692, "end_pos": 694, "annotation": "n_glycosylation_sequon" }, { "start_pos": 798, "end_pos": 800, "annotation": "n_glycosylation_sequon" }, { "start_pos": 987, "end_pos": 989, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZTQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTQ6" }, { "id": "PF05716", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05716" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "A-kinase anchor 110kDa C-terminal", "eco_id": "ECO_0000259", "start_pos": 1562, "end_pos": 1636, "start_aa": "Glu", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1047, "end_pos": 1049 }, { "start_pos": 1207, "end_pos": 1209 }, { "start_pos": 201, "end_pos": 203 }, { "start_pos": 24, "end_pos": 26 }, { "start_pos": 609, "end_pos": 611 }, { "start_pos": 667, "end_pos": 669 }, { "start_pos": 692, "end_pos": 694 }, { "start_pos": 798, "end_pos": 800 }, { "start_pos": 987, "end_pos": 989 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZTR6-1", "uniprot_ac": "A0A8V0ZTR6", "uniprot_id": "A0A8V0ZTR6_CHICK", "mass": { "chemical_mass": 43768.0, "monoisotopic_mass": 43768.0 }, "refseq": { "ac": "XP_024999570", "name": "transcription factor ETV7 isoform X6", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024999570" }, "gene_names": [ { "name": "ETV7", "type": "recommended", "evidence": [ { "id": "A0A8V0ZTR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTR6" } ] }, { "name": "ETV7", "type": "synonym", "evidence": [ { "id": "XP_024999570", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024999570" } ] } ], "protein_names": [ { "name": "Transcription factor ETV6", "type": "recommended", "evidence": [ { "id": "A0A8V0ZTR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTR6/entry#names_and_taxonomy" } ] }, { "name": "transcription factor ETV7 isoform X6", "type": "synonym", "evidence": [ { "id": "XP_024999570", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024999570" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052557.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_024999570.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_024999570", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024999570" } ] }, { "annotation": "Transcriptional repressor; binds to the DNA sequence 5'-CCGGAAGT-3'. Plays a role in hematopoiesis and malignant transformation.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTR6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTR6#function" }, { "database": "UniProtKB", "id": "ARBA00055208", "url": "https://www.uniprot.org/uniprotkb/ARBA00055208#function" }, { "database": "UniProtKB", "id": "A0A8V0ZYW6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYW6#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTR6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTR6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ETV7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTR6", "locus": { "chromosome": "26", "start_pos": 1575368, "end_pos": 1580625, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010024643", "url": "https://www.ensembl.org/id/ENSGALG00010024643" } ] } } ], "crossref": [ { "id": "A0A8V0ZTR6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZTR6", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd08535", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08535", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "419813", "url": "https://www.ncbi.nlm.nih.gov/gene/419813", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000418", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000418", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003118", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003118", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013761", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013761", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036388", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036388", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036390", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036390", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046328", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046328", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "RCEARMN", "url": "https://omabrowser.org/oma/group/RCEARMN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZTR6", "url": "https://www.orthodb.org/?gene=A0A8V0ZTR6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZYW6", "url": "https://www.orthodb.org/?gene=A0A8V0ZYW6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11849", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11849", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11849:SF77", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11849:SF77", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00178", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00178", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02198", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02198", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_024999570", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024999570", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZTR6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTR6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZTR6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTR6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZYW6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYW6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZYW6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYW6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MCVCVWGGVHGPGHSPRPSRLSDRFDFVSRKDRAGAAVGQRRAAGGGRDAGIQPSLWSKDDVIHWLRWAEREYSLQQTDESKFEMNGKALCILTKDDFRFRAPGSGDVLYELLQYIKTQRRALMYSPLLNSPFREAKGTGEGLWKMSWDPPRCSTRFSLSGMDGGAEAAPDAPSPCLEHTELSPSHSLREPLNLSHPSTEGGCGAESISSFPTAPLAPVDGKIADCRLLWDYIYQLLSDGRYEPYIKWEDKEAKLFRIVNPHGLAHLWGNHKNRMNMTYEKMSRALRHYYKLNIIKREPGQKLLFRFLKTPGEIIQEKSSRLEQLENEEHEELREKLLEVSVQDTTEGCECSAVQGDLCSAGKCQHLLLSAQKAAEGVLDSESCLELKL", "length": 389, "header": "tr|A0A8V0ZTR6-1|A0A8V0ZTR6_CHICK Isoform 1 of Transcription factor ETV6 OS=Gallus gallus OX=9031 GN=ETV7 PE=3 SV=1 CANONICAL=A0A8V0ZTR6-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZTR6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTR6/entry#A0A8V0ZTR6-1", "sequence": { "sequence": "MCVCVWGGVHGPGHSPRPSRLSDRFDFVSRKDRAGAAVGQRRAAGGGRDAGIQPSLWSKDDVIHWLRWAEREYSLQQTDESKFEMNGKALCILTKDDFRFRAPGSGDVLYELLQYIKTQRRALMYSPLLNSPFREAKGTGEGLWKMSWDPPRCSTRFSLSGMDGGAEAAPDAPSPCLEHTELSPSHSLREPLNLSHPSTEGGCGAESISSFPTAPLAPVDGKIADCRLLWDYIYQLLSDGRYEPYIKWEDKEAKLFRIVNPHGLAHLWGNHKNRMNMTYEKMSRALRHYYKLNIIKREPGQKLLFRFLKTPGEIIQEKSSRLEQLENEEHEELREKLLEVSVQDTTEGCECSAVQGDLCSAGKCQHLLLSAQKAAEGVLDSESCLELKL", "length": 389, "header": "tr|A0A8V0ZTR6-1|A0A8V0ZTR6_CHICK Isoform 1 of Transcription factor ETV6 OS=Gallus gallus OX=9031 GN=ETV7 PE=3 SV=1 CANONICAL=A0A8V0ZTR6-1" }, "locus": { "chromosome": "26", "start_pos": 1580386, "end_pos": 1576232, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010060160.1", "url": "https://www.ensembl.org/id/ENSGALT00010060160.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036920.1", "url": "https://www.ensembl.org/id/ENSGALP00010036920.1" } ] } }, { "isoform_ac": "A0A8V0ZYW6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTR6/entry#A0A8V0ZYW6-1", "sequence": { "sequence": "MQGEVTLGSSSPVAAALLPPRGRHTPADEGHSLALPGRLRIQPSLWSKDDVIHWLRWAEREYSLQQTDESKFEMNGKALCILTKDDFRFRAPGSGDVLYELLQYIKTQRRALMYSPLLNSPFREAKGTGEGLWKMSWDPPRCSTRFSLSGMDGGAEAAPDAPSPCLEHTELSPSHSLREPLNLSHPSTEGGCGAESISSFPTAPLAPVDGKIADCRLLWDYIYQLLSDGRYEPYIKWEDKEAKLFRIVNPHGLAHLWGNHKNRMNMTYEKMSRALRHYYKLNIIKREPGQKLLFRFLKTPGEIIQEKSSRLEQLENEEHEELREKLLEVSVQDTTEGCECSAVQGDLCSAGKCQHLLLSAQKAAEGVLDSESCLELKL", "length": 378, "header": "tr|A0A8V0ZYW6-1|A0A8V0ZTR6_CHICK Computationally mapped isoform of Transcription factor ETV6 OS=Gallus gallus OX=9031 GN=ETV7 PE=3 SV=1 CANONICAL=A0A8V0ZTR6-1" }, "locus": { "chromosome": "26", "start_pos": 1580241, "end_pos": 1576232, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010060157.1", "url": "https://www.ensembl.org/id/ENSGALT00010060157.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036917.1", "url": "https://www.ensembl.org/id/ENSGALP00010036917.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A287AJ08-1", "protein_name": "ETS variant transcription factor 7", "gene_name": "ETV7", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MQERALASSPVSPEAATLHPGTQARGRCEARVKLLLERGLCKLPGRLRIQPVLWSREDVLHWLRWAEQEYSLQHTGEHSFEMNGRALCILTKDDFRLRAPASGDVLYELLQYIKTQRQALMCGPFFGRAFMQRMPPQPCPYSLEEGTGFLQQPPDPGLASSWSHLDVPGPASWPLSKQESFSFSRWAELGCRAEGAGSFPTTSTRQAPIDGRIADCRLLWDYVYQLLSDTRYEPYIKWEDKNAKIFRVVDPNGLARLWGNHKNRVNMTYEKMSRALRHYYKLNIIKKEPGQKLLFRFLKTPGKTIQDEDSGRELLESQEQDRLDSKEEMLEVSP", "length": 334 }, "evidence": [ { "id": "A0A8V0ZTR6", "url": "https://omabrowser.org/oma/group/A0A8V0ZTR6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q9Y603-1", "protein_name": "Transcription factor ETV7", "gene_name": "ETV7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQEGELAISPISPVAAMPPLGTHVQARCEAQINLLGEGGICKLPGRLRIQPALWSREDVLHWLRWAEQEYSLPCTAEHGFEMNGRALCILTKDDFRHRAPSSGDVLYELLQYIKTQRRALVCGPFFGGIFRLKTPTQHSPVPPEEVTGPSQMDTRRGHLLQPPDPGLTSNFGHLDDPGLARWTPGKEESLNLCHCAELGCRTQGVCSFPAMPQAPIDGRIADCRLLWDYVYQLLLDTRYEPYIKWEDKDAKIFRVVDPNGLARLWGNHKNRVNMTYEKMSRALRHYYKLNIIKKEPGQKLLFRFLKTPGKMVQDKHSHLEPLESQEQDRIEFKDKRPEISP", "length": 341 }, "evidence": [ { "id": "A0A8V0ZTR6", "url": "https://omabrowser.org/oma/group/A0A8V0ZTR6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTR6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTR6" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTR6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTR6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTR6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTR6" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTR6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTR6" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTR6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTR6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "RNA polymerase II transcription regulatory region sequence-specific DNA binding", "id": "GO:0000977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000977", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTR6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTR6" } ], "pmid": "" }, { "name": "DNA-binding transcription repressor activity, RNA polymerase II-specific", "id": "GO:0001227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001227", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTR6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTR6" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTR6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTR6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 193, "end_pos": 195, "annotation": "n_glycosylation_sequon" }, { "start_pos": 276, "end_pos": 278, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZTR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTR6" }, { "id": "PS50061", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50061" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "ETS", "eco_id": "ECO_0000259", "start_pos": 227, "end_pos": 308, "start_aa": "Arg", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZTR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTR6" }, { "id": "PS51433", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51433" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PNT", "eco_id": "ECO_0000259", "start_pos": 36, "end_pos": 120, "start_aa": "Ala", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 193, "end_pos": 195 }, { "start_pos": 276, "end_pos": 278 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZTS2-1", "uniprot_ac": "A0A8V0ZTS2", "uniprot_id": "A0A8V0ZTS2_CHICK", "mass": { "chemical_mass": 97381.0, "monoisotopic_mass": 97381.0 }, "refseq": { "ac": "XP_004947155", "name": "potassium voltage-gated channel subfamily KQT member 2 isoform X10", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004947155" }, "gene_names": [ { "name": "KCNQ2", "type": "recommended", "evidence": [ { "id": "A0A8V0ZTS2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTS2" } ] }, { "name": "KCNQ2", "type": "synonym", "evidence": [ { "id": "XP_004947155", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004947155" } ] } ], "protein_names": [ { "name": "Potassium voltage-gated channel subfamily Q member 2", "type": "synonym", "evidence": [ { "id": "A0A8V0ZTS2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTS2/entry#names_and_taxonomy" } ] }, { "name": "potassium voltage-gated channel subfamily KQT member 2 isoform X10", "type": "synonym", "evidence": [ { "id": "XP_004947155", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004947155" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052551.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004947155.3. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004947155", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004947155" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTS2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTS2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "KCNQ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTS2", "locus": { "chromosome": "20", "start_pos": 9274166, "end_pos": 9333307, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010023174", "url": "https://www.ensembl.org/id/ENSGALG00010023174" } ] } } ], "crossref": [ { "id": "A0A8V0ZTS2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZTS2", "database": "AlphaFoldDB", "categories": [] }, { "id": "428151", "url": "https://www.ncbi.nlm.nih.gov/gene/428151", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003937", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003937", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003947", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003947", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005821", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005821", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013821", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013821", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020969", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020969", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZLH7", "url": "https://www.orthodb.org/?gene=A0A8V0ZLH7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZTS2", "url": "https://www.orthodb.org/?gene=A0A8V0ZTS2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZUT8", "url": "https://www.orthodb.org/?gene=A0A8V0ZUT8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZZA0", "url": "https://www.orthodb.org/?gene=A0A8V0ZZA0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47735", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47735", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47735:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47735:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00520", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00520", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03520", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03520", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF11956", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11956", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16642", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16642", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-1296072", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1296072", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_004947155", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004947155", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "29463", "url": "https://www.rhea-db.org/rhea/29463", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "34963", "url": "https://www.rhea-db.org/rhea/34963", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "78547", "url": "https://www.rhea-db.org/rhea/78547", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "78555", "url": "https://www.rhea-db.org/rhea/78555", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZLH7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLH7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLH7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLH7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZTS2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTS2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZTS2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTS2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZUT8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUT8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZUT8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUT8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZZA0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZA0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZZA0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZA0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVQKSRNGGVYPGPAAEKKLKVGFVGLDPGAPDSSRDGALLIAGSESTKRGSILSKPRSGVSGSGKPPKRNAFYRKLQNFLYNVLERPRGWAFIYHAYVFLLVFSCLVLSVFSTIDEYQNSSEGALYILEIVTIVVFGVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIASIAVLAAGSQGNVFATSALRSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLCLILASFLVYLAEKGENEHFDTYADALWWGLITLTTIGYGDKYPQTWNGRLLAATFTLIGVSFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAAGLIQAAWRFYATNLSRTDLHSTWQYYERTVTVPMYRLIPPLNQLELLRNLKSKSGLTFRKEQQPEPSPSQKVSLKDRVFSSPRGAGTKGKGSPQAQGIRRSPSADQSIEDSPSKVPKSWSFGDRSRARQAFRIKGAASRQNSEEASLPGEDIPDENKSCNCEFVTEDLTPGLKVSIRAVCIMRFLVSKRKFKESLRPYDVMDVIEQYSAGHLDMLSRIKNLQSRIDMIVGPPPPSTPRHKKYPTKGPMYSSKESPQYSPRVDQIVGRGSSMTDKDRTKGPAEGELPEDPSMMGRLGKVEKQVQSMEKKLDFLVNIYMQRMGIPPTETEAYFGSKEPDPAPPYHSPEDSREHIDKNGCIIKIIRSTSSMGQKNFSAPPAPTNSCPPSTSCQQQPYQRQSHGSSPVGDPGSLVRIPPPPSHERSLSAYSGGHRASAEYLRNEDITTKHHESALRDSDTSISIPSVDHEELERSFSGFSISQSKENLDILNNGCYAAVAKIRPYIAEGESDTDSDLCTPCGPPPRSATGEGPFSDMGWSAPRQ", "length": 877, "header": "tr|A0A8V0ZTS2-1|A0A8V0ZTS2_CHICK Isoform 1 of Potassium voltage-gated channel subfamily Q member 2 OS=Gallus gallus OX=9031 GN=KCNQ2 PE=4 SV=1 CANONICAL=A0A8V0ZTS2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZLH7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTS2/entry#A0A8V0ZLH7-1", "sequence": { "sequence": "MVQKSRNGGVYPGPAAEKKLKVGFVGLDPGAPDSSRDGALLIAGSESTKRGSILSKPRSGVSGSGKPPKRNAFYRKLQNFLYNVLERPRGWAFIYHAYVFLLVFSCLVLSVFSTIDEYQNSSEGALYILEIVTIVVFGVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIASIAVLAAGSQGNVFATSALRSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLCLILASFLVYLAEKGENEHFDTYADALWWGLITLTTIGYGDKYPQTWNGRLLAATFTLIGVSFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAAGLIQAAWRFYATNLSRTDLHSTWQYYERTVTVPMYSCVVL", "length": 377, "header": "tr|A0A8V0ZLH7-1|A0A8V0ZLH7_CHICK Computationally mapped isoform of Potassium voltage-gated channel subfamily Q member 2 OS=Gallus gallus OX=9031 GN=KCNQ2 PE=4 SV=1 CANONICAL=A0A8V0ZTS2-1" }, "locus": { "chromosome": "20", "start_pos": 9333268, "end_pos": 9306162, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056481.1", "url": "https://www.ensembl.org/id/ENSGALT00010056481.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034224.1", "url": "https://www.ensembl.org/id/ENSGALP00010034224.1" } ] } }, { "isoform_ac": "A0A8V0ZTS2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTS2/entry#A0A8V0ZTS2-1", "sequence": { "sequence": "MVQKSRNGGVYPGPAAEKKLKVGFVGLDPGAPDSSRDGALLIAGSESTKRGSILSKPRSGVSGSGKPPKRNAFYRKLQNFLYNVLERPRGWAFIYHAYVFLLVFSCLVLSVFSTIDEYQNSSEGALYILEIVTIVVFGVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIASIAVLAAGSQGNVFATSALRSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLCLILASFLVYLAEKGENEHFDTYADALWWGLITLTTIGYGDKYPQTWNGRLLAATFTLIGVSFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAAGLIQAAWRFYATNLSRTDLHSTWQYYERTVTVPMYRLIPPLNQLELLRNLKSKSGLTFRKEQQPEPSPSQKVSLKDRVFSSPRGAGTKGKGSPQAQGIRRSPSADQSIEDSPSKVPKSWSFGDRSRARQAFRIKGAASRQNSEEASLPGEDIPDENKSCNCEFVTEDLTPGLKVSIRAVCIMRFLVSKRKFKESLRPYDVMDVIEQYSAGHLDMLSRIKNLQSRIDMIVGPPPPSTPRHKKYPTKGPMYSSKESPQYSPRVDQIVGRGSSMTDKDRTKGPAEGELPEDPSMMGRLGKVEKQVQSMEKKLDFLVNIYMQRMGIPPTETEAYFGSKEPDPAPPYHSPEDSREHIDKNGCIIKIIRSTSSMGQKNFSAPPAPTNSCPPSTSCQQQPYQRQSHGSSPVGDPGSLVRIPPPPSHERSLSAYSGGHRASAEYLRNEDITTKHHESALRDSDTSISIPSVDHEELERSFSGFSISQSKENLDILNNGCYAAVAKIRPYIAEGESDTDSDLCTPCGPPPRSATGEGPFSDMGWSAPRQ", "length": 877, "header": "tr|A0A8V0ZTS2-1|A0A8V0ZTS2_CHICK Isoform 1 of Potassium voltage-gated channel subfamily Q member 2 OS=Gallus gallus OX=9031 GN=KCNQ2 PE=4 SV=1 CANONICAL=A0A8V0ZTS2-1" }, "locus": { "chromosome": "20", "start_pos": 9333268, "end_pos": 9275170, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056485.1", "url": "https://www.ensembl.org/id/ENSGALT00010056485.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034228.1", "url": "https://www.ensembl.org/id/ENSGALP00010034228.1" } ] } }, { "isoform_ac": "A0A8V0ZUT8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTS2/entry#A0A8V0ZUT8-1", "sequence": { "sequence": "MVQKSRNGGVYPGPAAEKKLKVGFVGLDPGAPDSSRDGALLIAGSESTKRGSILSKPRSGVSGSGKPPKRNAFYRKLQNFLYNVLERPRGWAFIYHAYVFLLVFSCLVLSVFSTIDEYQNSSEGALYILEIVTIVVFGVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIASIAVLAAGSQGNVFATSALRSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLCLILASFLVYLAEKGENEHFDTYADALWWGLITLTTIGYGDKYPQTWNGRLLAATFTLIGVSFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAAGLIQAAWRFYATNLSRTDLHSTWQYYERTVTVPMYSKSKPCRESLCGCCSGNSSPRGAGTKGKGSPQAQGIRRSPSADQSIEDSPSKVPKSWSFGDRSRARQAFRIKGAASRQNSEEASLPGEDIPDENKSCNCEFVTEDLTPGLKVSIRAVCIMRFLVSKRKFKESLRPYDVMDVIEQYSAGHLDMLSRIKNLQSRVDQIVGRGSSMTDKDRTKGPAEGELPEDPSMMGRLGKVEKQVQSMEKKLDFLVNIYMQRMGIPPTETEAYFGSKEPDPAPPYHSPEDSREHIDKNGCIIKIIRSTSSMGQKNFSAPPAPTNSCPPSTSCQQQPYQRQSHGSSPVGDPGSLVRIPPPPSHERSLSAYSGGHRASAEYLRNEDITTKHHESALRDSDTSISIPSVDHEELERSFSGFSISQSKENLDILNNGCYAAVAKIRPYIAEGESDTDSDLCTPCGPPPRSATGEGPFSDMGWSAPRQ", "length": 814, "header": "tr|A0A8V0ZUT8-1|A0A8V0ZTS2_CHICK Computationally mapped isoform of Potassium voltage-gated channel subfamily Q member 2 OS=Gallus gallus OX=9031 GN=KCNQ2 PE=4 SV=1 CANONICAL=A0A8V0ZTS2-1" }, "locus": { "chromosome": "20", "start_pos": 9333268, "end_pos": 9275170, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056489.1", "url": "https://www.ensembl.org/id/ENSGALT00010056489.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034232.1", "url": "https://www.ensembl.org/id/ENSGALP00010034232.1" } ] } }, { "isoform_ac": "A0A8V0ZZA0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTS2/entry#A0A8V0ZZA0-1", "sequence": { "sequence": "MVQKSRNGGVYPGPAAEKKLKVGFVGLDPGAPDSSRDGALLIAGSESTKRGSILSKPRSGVSGSGKPPKRNAFYRKLQNFLYNVLERPRGWAFIYHAYVFLLVFSCLVLSVFSTIDEYQNSSEGALYILEIVTIVVFGVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIASIAVLAAGSQGNVFATSALRSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLCLILASFLVYLAEKGENEHFDTYADALWWGLITLTTIGYGDKYPQTWNGRLLAATFTLIGVSFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAAGLIQAAWRFYATNLSRTDLHSTWQYYERTVTVPMYSTQTQTYGASRLIPPLNQLELLRNLKSKSGLTFRKEQQPEPSPSKSKPCRESLCGCCSGNSSPRGAGTKGKGSPQAQGIRRSPSADQSIEDSPSKVPKSWSFGDRSRARQAFRIKGAASRQNSEEASLPGEDIPDENKSCNCEFVTEDLTPGLKVSIRAVCIMRFLVSKRKFKESLRPYDVMDVIEQYSAGHLDMLSRIKNLQSRVDQIVGRGSSMTDKDRTKGPAEGELPEDPSMMGRLGKVEKQVQSMEKKLDFLVNIYMQRMGIPPTETEAYFGSKEPDPAPPYHSPEDSREHIDKNGCIIKIIRSTSSMGQKNFSAPPAPTNSCPPSTSCQQQPYQRQSHGSSPVGDPGSLVRIPPPPSHERSLSAYSGGHRASAEYLRNEDITTKHHESALRDSDTSISIPSVDHEELERSFSGFSISQSKENLDILNNGCYAAVAKIRPYIAEGESDTDSDLCTPCGPPPRSATGEGPFSDMGWSAPRQ", "length": 857, "header": "tr|A0A8V0ZZA0-1|A0A8V0ZTS2_CHICK Computationally mapped isoform of Potassium voltage-gated channel subfamily Q member 2 OS=Gallus gallus OX=9031 GN=KCNQ2 PE=4 SV=1 CANONICAL=A0A8V0ZTS2-1" }, "locus": { "chromosome": "20", "start_pos": 9333268, "end_pos": 9275170, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056487.1", "url": "https://www.ensembl.org/id/ENSGALT00010056487.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034230.1", "url": "https://www.ensembl.org/id/ENSGALP00010034230.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-1296072", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1296072", "resource": "Reactome", "description": "Voltage gated Potassium channels" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "calmodulin binding", "id": "GO:0005516", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005516", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTS2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTS2" } ], "pmid": "" }, { "name": "ankyrin binding", "id": "GO:0030506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030506", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTS2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTS2" } ], "pmid": "" }, { "name": "voltage-gated potassium channel activity", "id": "GO:0005249", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005249", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTS2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTS2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTS2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTS2" } ], "pmid": "" }, { "name": "voltage-gated potassium channel complex", "id": "GO:0008076", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008076", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTS2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTS2" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTS2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTS2" } ], "pmid": "" }, { "name": "monoatomic ion channel complex", "id": "GO:0034702", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034702", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTS2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTS2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "action potential", "id": "GO:0001508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001508", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTS2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTS2" } ], "pmid": "" }, { "name": "potassium ion transmembrane transport", "id": "GO:0071805", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071805", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTS2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTS2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 120, "end_pos": 122, "annotation": "n_glycosylation_sequon" }, { "start_pos": 350, "end_pos": 352, "annotation": "n_glycosylation_sequon" }, { "start_pos": 493, "end_pos": 495, "annotation": "n_glycosylation_sequon" }, { "start_pos": 709, "end_pos": 711, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "29463", "name": "", "equation": "K(+)(in) = K(+)(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "29463", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/29463" } ] }, { "id": "34963", "name": "", "equation": "Na(+)(in) = Na(+)(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "34963", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/34963" } ] }, { "id": "78547", "name": "", "equation": "Rb(+)(in) = Rb(+)(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "78547", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/78547" } ] }, { "id": "78555", "name": "", "equation": "Cs(+)(in) = Cs(+)(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "78555", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/78555" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZTS2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTS2" }, { "id": "PF00520", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00520" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ion transport", "eco_id": "ECO_0000259", "start_pos": 95, "end_pos": 321, "start_aa": "Tyr", "end_aa": "Gln", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZTS2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTS2" }, { "id": "PF03520", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03520" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Potassium channel voltage dependent KCNQ C-terminal", "eco_id": "ECO_0000259", "start_pos": 438, "end_pos": 587, "start_aa": "Ser", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 120, "end_pos": 122 }, { "start_pos": 350, "end_pos": 352 }, { "start_pos": 493, "end_pos": 495 }, { "start_pos": 709, "end_pos": 711 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZTS5-1", "uniprot_ac": "A0A8V0ZTS5", "uniprot_id": "A0A8V0ZTS5_CHICK", "mass": { "chemical_mass": 45509.0, "monoisotopic_mass": 45509.0 }, "refseq": { "ac": "XP_025001044", "name": "dynactin subunit 2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025001044" }, "gene_names": [ { "name": "DCTN2", "type": "recommended", "evidence": [ { "id": "A0A8V0ZTS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTS5" } ] }, { "name": "DCTN2", "type": "synonym", "evidence": [ { "id": "XP_025001044", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025001044" } ] }, { "name": "P50", "type": "synonym", "evidence": [ { "id": "XP_025001044", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025001044" } ] } ], "protein_names": [ { "name": "Dynactin subunit 2", "type": "synonym", "evidence": [ { "id": "A0A8V0ZTS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTS5/entry#names_and_taxonomy" } ] }, { "name": "dynactin subunit 2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_025001044", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025001044" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052565.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_025001044", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025001044" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTS5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTS5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "DCTN2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTS5", "locus": { "chromosome": "34", "start_pos": 2425927, "end_pos": 2435171, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010023638", "url": "https://www.ensembl.org/id/ENSGALG00010023638" } ] } } ], "crossref": [ { "id": "A0A8V0ZTS5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZTS5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000034955", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000034955", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "395587", "url": "https://www.ncbi.nlm.nih.gov/gene/395587", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR028133", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028133", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:395587", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395587", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YKFGDWE", "url": "https://omabrowser.org/oma/group/YKFGDWE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PFB8", "url": "https://www.orthodb.org/?gene=A0A1D5PFB8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PGQ9", "url": "https://www.orthodb.org/?gene=A0A1D5PGQ9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PHJ8", "url": "https://www.orthodb.org/?gene=A0A1D5PHJ8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZTS5", "url": "https://www.orthodb.org/?gene=A0A8V0ZTS5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A1A5", "url": "https://www.orthodb.org/?gene=A0A8V1A1A5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15346", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15346", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04912", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04912", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-2565942", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2565942", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-3371497", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3371497", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-380259", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-380259", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-380270", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-380270", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-380284", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-380284", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-380320", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-380320", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5620912", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5620912", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-6807878", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6807878", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-6811436", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6811436", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-8854518", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8854518", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_025001044", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025001044", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PFB8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PFB8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PFB8-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PFB8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PGQ9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PGQ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PGQ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PGQ9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PHJ8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PHJ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PHJ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PHJ8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZTS5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTS5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZTS5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTS5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A1A5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1A5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A1A5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1A5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MADPKYADLPGIARNEPDVYETSDLPEDDQAEFEAFAQELEELTSTSVEHLIINPNAAFEKFKDKRLGTDGVDFSDRISKSRTTGYESGEYEILGEGLGAKETPQQRYQRLQHEVQELIRDVEQIQSAVKESAAEEELTPMALARQLEGLKQQLVSCHLQKLLGPTAAIDFADPEGALAKRLQQQLEVAKCKKAAPAKSPPKAPAPTTDALTFELFWRPEQDQFSQTAKIAELEKRLAQLEAMVRCEPDSQNPLLVGLKGTSLVETVQILQAKVNILDAAVLDQVEARLQSVLGKVNEIAKHKAIVQDADTQSKIHQVYEMMQRWDHMASSLPDVVQRLLTLRDLHEQASRFVQVLVHLDTTQQEVAAALKDNTVLLAEVQKTMKENLAVVEDNFAEVEARIKRLQK", "length": 407, "header": "tr|A0A8V0ZTS5-1|A0A8V0ZTS5_CHICK Isoform 1 of Dynactin subunit 2 OS=Gallus gallus OX=9031 GN=DCTN2 PE=1 SV=1 CANONICAL=A0A8V0ZTS5-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PFB8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTS5/entry#A0A1D5PFB8-1", "sequence": { "sequence": "MADPKYADLPGIARNEPDVYETSDLPEDDQAEFEAELEELTSTSVEHLIINPNAAFEKFKDKRLGTDGVDFSDRISKSRTTGYESGEYEILGEGLGAKETPQQRYQRLQHEVQELIRDVEQIQSAVKESAAEEELTPMALARQLEGLKQQLVSCHLQKLLGPTAAIDFADPEGALAKRLQQQLEVAKCKKAAPAKSPPKAPAPTTDALTFELFWRPEQDQFSQTAKIAELEKRLAQLEAMVRCEPDSQNPLLVGLKGTSLVETVQILQAKVNILDAAVLDQVEARLQSVLGKVNEIAKHKAIVQDADTQSKIHQVYEMMQRWDHMASSLPDVVQRLLTLRDLHEQASRFVQVLVHLDTTQQEVAAALKDNTVLLAEVQKTMKENLAVVEDNFAEVEARIKRLQK", "length": 404, "header": "tr|A0A1D5PFB8-1|A0A1D5PFB8_CHICK Computationally mapped isoform of Dynactin subunit 2 OS=Gallus gallus OX=9031 GN=DCTN2 PE=1 SV=2 CANONICAL=A0A8V0ZTS5-1" }, "locus": { "chromosome": "34", "start_pos": 2433964, "end_pos": 2426133, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010057598.1", "url": "https://www.ensembl.org/id/ENSGALT00010057598.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034985.1", "url": "https://www.ensembl.org/id/ENSGALP00010034985.1" } ] } }, { "isoform_ac": "A0A1D5PGQ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTS5/entry#A0A1D5PGQ9-1", "sequence": { "sequence": "MADPKYADLPGIARNEPDVYETSDLPEDDQAEFEAEELTSTSVEHLIINPNAAFEKFKDKRLGTDGVDFSDRISKSRTTGYESGEYEILGEGLGAKETPQQRYQRLQHEVQELIRDVEQIQSAVKESAAEEELTPMALARQLEGLKQQLVSCHLQKLLGPTAAIDFADPEGALAKRLQQQLEVAKCKKAAPAKSPPKAPAPTTDALTFELFWRPEQDQFSQTAKIAELEKRLAQLEAMVRCEPDSQNPLLVGLKGTSLVETVQILQAKVNILDAAVLDQVEARLQSVLGKVNEIAKHKAIVQDADTQSKIHQVYEMMQRWDHMASSLPDVVQRLLTLRDLHEQASRFVQVLVHLDTTQQEVAAALKDNTVLLAEVQKTMKENLAVVEDNFAEVEARIKRLQK", "length": 402, "header": "tr|A0A1D5PGQ9-1|A0A1D5PGQ9_CHICK Computationally mapped isoform of Dynactin subunit 2 OS=Gallus gallus OX=9031 GN=DCTN2 PE=1 SV=1 CANONICAL=A0A8V0ZTS5-1" }, "locus": { "chromosome": "34", "start_pos": 2433964, "end_pos": 2426133, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010057603.1", "url": "https://www.ensembl.org/id/ENSGALT00010057603.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034987.1", "url": "https://www.ensembl.org/id/ENSGALP00010034987.1" } ] } }, { "isoform_ac": "A0A1D5PHJ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTS5/entry#A0A1D5PHJ8-1", "sequence": { "sequence": "MADPKYADLPGIEELTSTSVEHLIINPNAAFEKFKDKRLGTDGVDFSDRISKSRTTGYESGEYEILGEGLGAKETPQQRYQRLQHEVQELIRDVEQIQSAVKESAAEEELTPMALARQLEGLKQQLVSCHLQKLLGPTAAIDFADPEGALAKRLQQQLEVAKCKKAAPAKSPPKAPAPTTDALTFELFWRPEQDQFSQTAKIAELEKRLAQLEAMVRCEPDSQNPLLVGLKGTSLVETVQILQAKVNILDAAVLDQVEARLQSVLGKVNEIAKHKAIVQDADTQSKIHQVYEMMQRWDHMASSLPDVVQRLLTLRDLHEQASRFVQVLVHLDTTQQEVAAALKDNTVLLAEVQKTMKENLAVVEDNFAEVEARIKRLQK", "length": 379, "header": "tr|A0A1D5PHJ8-1|A0A1D5PHJ8_CHICK Computationally mapped isoform of Dynactin subunit 2 OS=Gallus gallus OX=9031 GN=DCTN2 PE=1 SV=2 CANONICAL=A0A8V0ZTS5-1" }, "locus": { "chromosome": "34", "start_pos": 2433964, "end_pos": 2426133, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010057567.1", "url": "https://www.ensembl.org/id/ENSGALT00010057567.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034967.1", "url": "https://www.ensembl.org/id/ENSGALP00010034967.1" } ] } }, { "isoform_ac": "A0A8V0ZTS5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTS5/entry#A0A8V0ZTS5-1", "sequence": { "sequence": "MADPKYADLPGIARNEPDVYETSDLPEDDQAEFEAFAQELEELTSTSVEHLIINPNAAFEKFKDKRLGTDGVDFSDRISKSRTTGYESGEYEILGEGLGAKETPQQRYQRLQHEVQELIRDVEQIQSAVKESAAEEELTPMALARQLEGLKQQLVSCHLQKLLGPTAAIDFADPEGALAKRLQQQLEVAKCKKAAPAKSPPKAPAPTTDALTFELFWRPEQDQFSQTAKIAELEKRLAQLEAMVRCEPDSQNPLLVGLKGTSLVETVQILQAKVNILDAAVLDQVEARLQSVLGKVNEIAKHKAIVQDADTQSKIHQVYEMMQRWDHMASSLPDVVQRLLTLRDLHEQASRFVQVLVHLDTTQQEVAAALKDNTVLLAEVQKTMKENLAVVEDNFAEVEARIKRLQK", "length": 407, "header": "tr|A0A8V0ZTS5-1|A0A8V0ZTS5_CHICK Isoform 1 of Dynactin subunit 2 OS=Gallus gallus OX=9031 GN=DCTN2 PE=1 SV=1 CANONICAL=A0A8V0ZTS5-1" }, "locus": { "chromosome": "34", "start_pos": 2433964, "end_pos": 2426133, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010057587.1", "url": "https://www.ensembl.org/id/ENSGALT00010057587.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034979.1", "url": "https://www.ensembl.org/id/ENSGALP00010034979.1" } ] } }, { "isoform_ac": "A0A8V1A1A5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTS5/entry#A0A8V1A1A5-1", "sequence": { "sequence": "MADPKYADLPGIARNEPDVYETSDLPEDDQAEFEAEELTSTSVEHLIINPNAAFEKFKDKRLGTDGVDFSDRISKSRTTGYESGEYEILGEGLGAKETPQQRYQRLQHEVQELIRDVEQIQSAVKESAAEEELTPMALARQLEGLKQQLVSCHLQKLLGPTAAIDFADPEGALAKRLQQQLEVAKCKKAAPAKSPPKAPAPTTDALTFELFWRPEQDQFSQTAKNPLLVGLKGTSLVETVQILQAKVNILDAAVLDQVEARLQSVLGKVNEIAKHKAIVQDADTQSKIHQVYEMMQRWDHMASSLPDVVQRLLTLRDLHEQASRFVQVLVHLDTTQQEVAAALKDNTVLLAEVQKTMKENLAVVEDNFAEVEARIKRLQK", "length": 380, "header": "tr|A0A8V1A1A5-1|A0A8V0ZTS5_CHICK Computationally mapped isoform of Dynactin subunit 2 OS=Gallus gallus OX=9031 GN=DCTN2 PE=1 SV=1 CANONICAL=A0A8V0ZTS5-1" }, "locus": { "chromosome": "34", "start_pos": 2433964, "end_pos": 2426133, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010057574.1", "url": "https://www.ensembl.org/id/ENSGALT00010057574.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034972.1", "url": "https://www.ensembl.org/id/ENSGALP00010034972.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 166, "start_aa": "Thr", "end_pos": 166, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr166", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:395587", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395587", "resource": "KEGG Pathway" }, { "id": "R-GGA-2565942", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2565942", "resource": "Reactome", "description": "Regulation of PLK1 Activity at G2/M Transition" }, { "id": "R-GGA-3371497", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3371497", "resource": "Reactome", "description": "HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand" }, { "id": "R-GGA-380259", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-380259", "resource": "Reactome", "description": "Loss of Nlp from mitotic centrosomes" }, { "id": "R-GGA-380270", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-380270", "resource": "Reactome", "description": "Recruitment of mitotic centrosome proteins and complexes" }, { "id": "R-GGA-380284", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-380284", "resource": "Reactome", "description": "Loss of proteins required for interphase microtubule organization from the centrosome" }, { "id": "R-GGA-380320", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-380320", "resource": "Reactome", "description": "Recruitment of NuMA to mitotic centrosomes" }, { "id": "R-GGA-5620912", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5620912", "resource": "Reactome", "description": "Anchoring of the basal body to the plasma membrane" }, { "id": "R-GGA-6807878", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6807878", "resource": "Reactome", "description": "COPI-mediated anterograde transport" }, { "id": "R-GGA-6811436", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6811436", "resource": "Reactome", "description": "COPI-independent Golgi-to-ER retrograde traffic" }, { "id": "R-GGA-8854518", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8854518", "resource": "Reactome", "description": "AURKA Activation by TPX2" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A9J7F1K3-1", "protein_name": "Dynactin subunit 2", "gene_name": "Dctn2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MADPKYADLPGIARNEPDVYETSDLPEDDQAEFDAELEELTSTSVEHIIVNPNAAYDKFKDKRVGTKGLDFSDRIGKTKRTGYESGDYEMLGEGVGVKETPQQKYQRLLHEVQELTTEVEKIRTTVKESAIEEKLTPVVLAKQLVALKQQLVASHLEKLLGPDAAINLTDPDGALAKRLLLQLEATKNSKGTLGGRATGGTPPDSSLVTYELHSRPEQDKFLQAAKVAELEKRLTELEATVRCDQDAQNPLSAGLQGACLMETVELLQAKVNALDLAVLDQVEARLQSVLGKVNEIAKHKASVEDADTQSKVHQLYETTQRWSPIASALPELVQRLVTIKQLHEQAMQFGQLLTHLDTTQQMIASSLKDNATLLTQVQTTMRENLTTVEGNFASIDERMKQLGK", "length": 404 }, "evidence": [ { "id": "A0A8V0ZTS5", "url": "https://omabrowser.org/oma/group/A0A8V0ZTS5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q13561-1", "protein_name": "Dynactin subunit 2", "gene_name": "DCTN2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MADPKYADLPGIARNEPDVYETSDLPEDDQAEFDAEELTSTSVEHIIVNPNAAYDKFKDKRVGTKGLDFSDRIGKTKRTGYESGEYEMLGEGLGVKETPQQKYQRLLHEVQELTTEVEKIKTTVKESATEEKLTPVLLAKQLAALKQQLVASHLEKLLGPDAAINLTDPDGALAKRLLLQLEATKNSKGGSGGKTTGTPPDSSLVTYELHSRPEQDKFSQAAKVAELEKRLTELETAVRCDQDAQNPLSAGLQGACLMETVELLQAKVSALDLAVLDQVEARLQSVLGKVNEIAKHKASVEDADTQSKVHQLYETIQRWSPIASTLPELVQRLVTIKQLHEQAMQFGQLLTHLDTTQQMIANSLKDNTTLLTQVQTTMRENLATVEGNFASIDERMKKLGK", "length": 401 }, "evidence": [ { "id": "A0A8V0ZTS5", "url": "https://omabrowser.org/oma/group/A0A8V0ZTS5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q54N50-1", "protein_name": "Dynactin subunit 2", "gene_name": "dynB", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSEGNQPKRVLGLPDVDPSQQDTFETPDPPESISNLADESSELVNESIDRSSLKPAKSHLKFANRKFNNDNEDFSDSIYKKSVPRTGGLLKNQTVFDILPSDESKVETPLQKFQRLQYEVMSFREEMQVIADNGGEVEKDIKGVDLTHQLADLQNQLSHLLENEKLQPILDENKQVIHYSQIQNNSSKKLISEIESFTQQSLSSSTTEQNTQQPSNNNTTTNITSSSSITPNHVTYELFYTGEQSKSQQLQRIQDLEKRLAKLETATGNKTTDSVPITQSILEIKEKLSLLDTTKIDVLQQKMKTVSKEMESLKIQDETSTKALTTNEKKINDIFETMNKWDIVGQQVPAIINRLYTLRSLHEEGISFSNHVSNLEKQQNDITSLLISNSSLMNKMDDSFKSNLLTIKSNIQQLESRIETLQNRQQQQQQ", "length": 430 }, "evidence": [ { "id": "A0A8V0ZTS5", "url": "https://omabrowser.org/oma/group/A0A8V0ZTS5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q6AYH5-1", "protein_name": "Dynactin subunit 2", "gene_name": "Dctn2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": 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[], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 184, "end_pos": 186 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZTU2-1", "uniprot_ac": "A0A8V0ZTU2", "uniprot_id": "A0A8V0ZTU2_CHICK", "mass": { "chemical_mass": 109971.0, "monoisotopic_mass": 109971.0 }, "refseq": {}, "gene_names": [ { "name": "EIF4ENIF1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZTU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTU2" } ] } ], "protein_names": [ { "name": "Eukaryotic translation initiation factor 4E nuclear import factor 1", "type": "synonym", "evidence": [ { "id": "A0A8V0ZTU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTU2/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTU2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTU2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "EIF4ENIF1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTU2", "locus": { "chromosome": "15", "start_pos": 9006800, "end_pos": 8984898, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022027", "url": "https://www.ensembl.org/id/ENSGALG00010022027" } ] } } ], "crossref": [ { "id": "A0A8V0ZTU2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZTU2", "database": "AlphaFoldDB", "categories": [] }, { "id": "416961", "url": "https://www.ncbi.nlm.nih.gov/gene/416961", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR018862", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018862", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416961", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416961", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WITRGSW", "url": "https://omabrowser.org/oma/group/WITRGSW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZG23", "url": "https://www.orthodb.org/?gene=A0A8V0ZG23", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZTU2", "url": "https://www.orthodb.org/?gene=A0A8V0ZTU2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZTV2", "url": "https://www.orthodb.org/?gene=A0A8V0ZTV2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12269", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12269", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12269:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12269:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10477", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10477", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZG23", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG23", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZG23-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG23-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZTU2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTU2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZTU2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTU2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZTV2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTV2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZTV2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTV2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKGLVCFSFARSMVKGFDVAMDKRGGITEAENGDAFLELNRTATKYPHRYTKEELLDIKERPYSKQRPSCLSEKYDSDGVWDPEKWHASLYPSSGRTSPVESFKKDLDSDRTSLIRRIVDPRERVKEDDLDVVLSPQRRSFGGGCHVTAAVSSRRAGSPLEKENDGVRVIGGRRIGSGRIISSRNFDKDHRGGEKDIRDSRDARDRDRERDYKDKRFRREFGDSKRVFGERRRNDSYTEEEPEWFSAGPTSQSETIELTGFDDKILEEDHKGRKRTRRRTASLKEGIECNGGVAEEEEVQTVLANETPADQEVPREAVLQEPAPGEFDFNEFFNLDKSVPGLASMIEDVLGEGSVSASRFSRWFSNPSRSGSRSSSLRSTPHEELERLAGLEQAILSPGQNSGNYFAPIPLEDHSENKVDILEMLQKAKVDLKPLLSSLSANKEKLRESTHSGVVLSVEEVEAGLKGLKVDQEGKIATPFMAEQMEESLNIAGSRQIKKDGDMTAFNKLVSSMKASGTLPSQPKVNQSLESHLMSPPEIPGQPLSKNILQELLGPPITRPASSNVLSGLISGLEPGASLLGQRAPSPPIPPVFPTRAASADYLRHRISSPIGFGQGSQQLLGDPFPGVRKPMSPVAAQMSPLEIQQAALEGLALPHDLAIQAANFYQHGFGKPQMDKNRDGYRNRQQRVTKSPAPGHRGNTSSPAPTASITSMLSPSFTPTSVIRKMYESKEKSKEEPVSGKLKVSDGKDENQRPNEATDNLLSSSVENADQETLPTLGTKLPALQRSACSTPLTQANRCTKEQDYRPKSAGRKTPTMASPVPGGPFLRPVHQVPLVPHVPIVRPAHQLHPGLVQRMLSQGVHPQHLPLLQAGMLPPGVDLSHLQGISAPILGQPFYPLPTASHHILNPRSGTPLQLAMMQQQLQRSGTGAQGSPAGVQTTPQNVPSRTGLSHGHAQLDHRPSQRSGSPIGLAKWFGSDVLQQPLPSMPSKVISVDELEYRQ", "length": 1002, "header": "tr|A0A8V0ZTU2-1|A0A8V0ZTU2_CHICK Isoform 1 of Eukaryotic translation initiation factor 4E nuclear import factor 1 OS=Gallus gallus OX=9031 GN=EIF4ENIF1 PE=1 SV=1 CANONICAL=A0A8V0ZTU2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZG23-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTU2/entry#A0A8V0ZG23-1", "sequence": { "sequence": "MVKGFDVAMDKRGGITEAENGDAFLELNRTATKYPHRYTKEELLDIKERPYSKQRPSCLSEKYDSDGVWDPEKWHASLYPSSGRTSPVESFKKDLDSDRTSLIRRIVDPRERVKEDDLDVVLSPQRRSFGGGCHVTAAVSSRRAGSPLEKENDGVRVIGGRRIGSGRIISSRNFDKDHRGGEKDIRDSRDARDRDRERDYKDKRFRREFGDSKRVFGERRRNDSYTEEEPEWFSAGPTSQSETIELTGFDDKILEEDHKGRKRTRRRTASLKEGIECNGGVAEEEEVQTVLANETPADQEVPREAVLQEPAPGEFDFNEFFNLDKSVPGLASMIEDVLGEGSVSASRFSRWFSNPSRSGSRSSSLRSTPHEELERLAGLEQAILSPGQNSGNYFAPIPLEDHSENKVDILEMLQKAKVDLKPLLSSLSANKEKLRESTHSGVVLSVEEVEAGLKGLKVDQEGKIATPFMAEQMEESLNIAGSRQIKKDGDMTAFNKLVSSMKASGTLPSQPKVNQSLESHLMSPPEIPGQPLSKNILQELLGPPITRPASSNVLSGLISGLEPGASLLGQRAPSPPIPPVFPTRAASADYLRHRISSPIGFGQGSQQLLGDPFPGVRKPMSPVAAQMSPLEIQQAALEGLALPHDLAIQAANFYQHGFGKPQMDKNRDGYRNRQQRVTKSPAPGHRGNTSSPAPTASITSMLSPSFTPTSVIRKMYESKEKSKEEPVSGKLKVSDGKDENQRPNEATDNLLSSSVENADQETLPTLGTKLPALQRSACSTPLTQANRCTKEQDYRPKSAGRKTPTMASPVPGGPFLRPVHQVPLVPHVPIVRPAHQLHPGLVQRMLSQGVHPQHLPLLQAGMLPPGVDLSHLQGISAPILGQPFYPLPTASHHILNPRSGTPLQLAMMQQQLQRSGTGAQGSPAGVQTTPQNVPSRTGLSHGHAQLDHRPSQRSGSPIGLAKWFGSDVLQQPLPSMPSKVISVDELEYRQ", "length": 990, "header": "tr|A0A8V0ZG23-1|A0A8V0ZG23_CHICK Computationally mapped isoform of Eukaryotic translation initiation factor 4E nuclear import factor 1 OS=Gallus gallus OX=9031 GN=EIF4ENIF1 PE=1 SV=1 CANONICAL=A0A8V0ZTU2-1" }, "locus": { "chromosome": "15", "start_pos": 9005129, "end_pos": 8986068, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053543.1", "url": "https://www.ensembl.org/id/ENSGALT00010053543.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032260.1", "url": "https://www.ensembl.org/id/ENSGALP00010032260.1" } ] } }, { "isoform_ac": "A0A8V0ZTU2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTU2/entry#A0A8V0ZTU2-1", "sequence": { "sequence": "MKGLVCFSFARSMVKGFDVAMDKRGGITEAENGDAFLELNRTATKYPHRYTKEELLDIKERPYSKQRPSCLSEKYDSDGVWDPEKWHASLYPSSGRTSPVESFKKDLDSDRTSLIRRIVDPRERVKEDDLDVVLSPQRRSFGGGCHVTAAVSSRRAGSPLEKENDGVRVIGGRRIGSGRIISSRNFDKDHRGGEKDIRDSRDARDRDRERDYKDKRFRREFGDSKRVFGERRRNDSYTEEEPEWFSAGPTSQSETIELTGFDDKILEEDHKGRKRTRRRTASLKEGIECNGGVAEEEEVQTVLANETPADQEVPREAVLQEPAPGEFDFNEFFNLDKSVPGLASMIEDVLGEGSVSASRFSRWFSNPSRSGSRSSSLRSTPHEELERLAGLEQAILSPGQNSGNYFAPIPLEDHSENKVDILEMLQKAKVDLKPLLSSLSANKEKLRESTHSGVVLSVEEVEAGLKGLKVDQEGKIATPFMAEQMEESLNIAGSRQIKKDGDMTAFNKLVSSMKASGTLPSQPKVNQSLESHLMSPPEIPGQPLSKNILQELLGPPITRPASSNVLSGLISGLEPGASLLGQRAPSPPIPPVFPTRAASADYLRHRISSPIGFGQGSQQLLGDPFPGVRKPMSPVAAQMSPLEIQQAALEGLALPHDLAIQAANFYQHGFGKPQMDKNRDGYRNRQQRVTKSPAPGHRGNTSSPAPTASITSMLSPSFTPTSVIRKMYESKEKSKEEPVSGKLKVSDGKDENQRPNEATDNLLSSSVENADQETLPTLGTKLPALQRSACSTPLTQANRCTKEQDYRPKSAGRKTPTMASPVPGGPFLRPVHQVPLVPHVPIVRPAHQLHPGLVQRMLSQGVHPQHLPLLQAGMLPPGVDLSHLQGISAPILGQPFYPLPTASHHILNPRSGTPLQLAMMQQQLQRSGTGAQGSPAGVQTTPQNVPSRTGLSHGHAQLDHRPSQRSGSPIGLAKWFGSDVLQQPLPSMPSKVISVDELEYRQ", "length": 1002, "header": "tr|A0A8V0ZTU2-1|A0A8V0ZTU2_CHICK Isoform 1 of Eukaryotic translation initiation factor 4E nuclear import factor 1 OS=Gallus gallus OX=9031 GN=EIF4ENIF1 PE=1 SV=1 CANONICAL=A0A8V0ZTU2-1" }, "locus": { "chromosome": "15", "start_pos": 9005129, "end_pos": 8986032, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053538.1", "url": "https://www.ensembl.org/id/ENSGALT00010053538.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032256.1", "url": "https://www.ensembl.org/id/ENSGALP00010032256.1" } ] } }, { "isoform_ac": "A0A8V0ZTV2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTU2/entry#A0A8V0ZTV2-1", "sequence": { "sequence": "MVKGFDVAMDKRGGITEAENGDAFLELNRTATKYPHRYTKEELLDIKERPYSKQRPSCLSEKYDSDGVWDPEKWHASLYPSSGRTSPVESFKKDLDSDRTSLIRRIVDPRERVKEDDLDVVLSPQRRSFGGGCHVTAAVSSRRAGSPLEKENDGVRVIGGRRIGSGRIISSRNFDKDHRGGEKDIRDSRDARDRDRERDYKDKRFRREFGDSKRVFGERRRNDSYTEEEPEWFSAGPTSQSETIELTGFDDKILEEDHKGRKRTRRRTASLKEGIECNGGVAEEEEVQTVLANETPADQEVPREAVLQEPAPGEFDFNEFFNLDKSVPGLASMIEDVLGEGSVSASRFSRWFSNPSRSGSRSSSLRSTPHEELERLAAHSGVVLSVEEVEAGLKGLKVDQEGKIATPFMAEQMEESLNIAGSRQIKKDGDMTAFNKLVSSMKASGTLPSQPKVNQSLESHLMSPPEIPGQPLSKNILQELLGPPITRPASSNVLSGLISGLEPGASLLGQRAPSPPIPPVFPTRAASADYLRHRISSPIGFGQGSQQLLGDPFPGVRKPMSPVAAQMSPLEIQQAALEGLALPHDLAIQAANFYQHGFGKPQMDKNRDGYRNRQQRVTKSPAPGHRGNTSSPAPTASITSMLSPSFTPTSVIRKMYESKEKSKEEPVSGKLKVSDGKDENQRPNEATDNLLSSSVENADQETLPTLGTKLPALQRSACSTPLTQANRCTKEQDYRPKSAGRKTPTMASPVPGGPFLRPVHQVPLVPHVPIVRPAHQLHPGLVQRMLSQGVHPQHLPLLQAGMLPPGVDLSHLQGISAPILGQPFYPLPTASHHILNPRSGTPLQLAMMQQQLQRSGTGAQGSPAGVQTTPQNVPSRTGLSHGHAQLDHRPSQRSGSPIGLAKWFGSDVLQQPLPSMPSKVISVDELEYRQ", "length": 930, "header": "tr|A0A8V0ZTV2-1|A0A8V0ZTV2_CHICK Computationally mapped isoform of Eukaryotic translation initiation factor 4E nuclear import factor 1 OS=Gallus gallus OX=9031 GN=EIF4ENIF1 PE=1 SV=1 CANONICAL=A0A8V0ZTU2-1" }, "locus": { "chromosome": "15", "start_pos": 9005129, "end_pos": 8986068, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053551.1", "url": "https://www.ensembl.org/id/ENSGALT00010053551.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032266.1", "url": "https://www.ensembl.org/id/ENSGALP00010032266.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 250, "start_aa": "Thr", "end_pos": 250, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr250", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 707, "start_aa": "Thr", "end_pos": 707, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr707", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:416961", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416961", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A286ZWZ3-1", "protein_name": "Eukaryotic translation initiation factor 4E nuclear import factor 1", "gene_name": "EIF4ENIF1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDRSVGESENGDAFLDLKKQPASKSPHRYTKEELLDIKERPHSKQRPSCLSEKYDSDGVWDPEKWHASLYPASGRNSPVESLKKEVDTDRPSLVRRIVDPRERVKEDDLDVVLSPQRRSFGGGCHVTAAVSSRRSGSPLEKDSDGLRLLGGRRIGSGRIISARTFEKDHRLSDKDLRDLRDRDRERDYKDKRFRREFGDSKRVFGERRRNDSYTEEEPEWFSAGPTSQSETIELTGFDDKILEEDHKGRKRTRRRTASVKEGIVECNGGVAEEDEVEVILTQEPAADQEVPRDAVLPEQSPGEFDFNEFFNLDKVPCLASMIEDVLGEGSVSASRFSRWFSNPSRSGSRSSSLGSTPHEELERLAGLEQAILSPGQNSGNYFAPIPLEDHAENKVDILEMLQKAKVDLKPLLSSLSANKEKLKESSHSGVVLSVEEVEAGLKGLKVDQQVKKSTPFMAEHLEETLSTVTSNRQLKKDGDMTAFNKLVSTMKASGTLPSQPKVSRNLESHLMSAAEIPGQPVPKNILQELLGPPVQRPASSNLLSGLMGSLEPTTSLLGQRAPSPPLSQVFHTRAASADYLRTRIPSPIGFTPGPQQLLGDPFQGMRKPMSPVTTQMSQLELQQAALEGLALPHDLAVQAANFYQPGFGKPQVDRTREGFRNRQQRVTKSPAPVHRGNSSSPAPAASITSMLSPSFTPTSVIRKMYESKEKSKEEPASGKAALGDSKEDTQKPSEENLLSSSSVPTADRESSPTTNPKLSTLQQRSSCSTPLSQTNRYTKEQDYRPKATGRKTPTLPSPVPGTPFLRPVHQVPLVPHVPIVRPAHQLHPGLVQRMLAQGVHPQHLPSLLQAGVLPPGIDLTHLQGISGPILGQPFYPLPATGHPLLNPRPGTPLHLAMMQQQLQRSVLHPPGSGSQAAAVSVQTSQNVPSRSGLPHMHSQLEHRPSQRSSSPVGLAKWFGSDVLQQPLPSMPAKVISVDELEYRQ", "length": 984 }, "evidence": [ { "id": "A0A8V0ZTU2", "url": "https://omabrowser.org/oma/group/A0A8V0ZTU2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8I6A9M0-1", "protein_name": "Eukaryotic translation initiation factor 4E nuclear import factor 1", "gene_name": "Eif4enif1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MATGVAGLERCKKIVHQEAMEKRSVDETENGDAFLDLKKLPTSKSPHRYTKEELLDIKERPYSKQRPSCLSEKYDSDGVWDPEKWHASLYPASGRSSPVESLKKEPESDRPSLVRRIADPRERVKEDDLDVVLSPQRRSFGGGCHVTAAVSSRRSGSPLEKDSDGLRLLGGRRIGSGRIISARAFEKDHRLSDKDLRDLRDRDRERDYKDKRFRREFGDSKRVFGERRRNDSYTEEEPEWFSAGPTSQSETIELTGFDDKILEEDHKGRKRTRRRTASVREGIVECNGGVAEEDEVEVILAQEPSADQEVPRDVILPEQSPGEFDFNEFFNLDKVPCLASMIEDVLGEGSVSASRFSRWFSNPSRSGSRSSSLGSTPHEELERLAGLEQAVLSPGQNSGNYFAPIPSEDHAENKVDILEMLQKAKVDLKPLLSSLSANKEKLKESSHSGVVLSVEEVEAGLKGLKVDQQIKNSTPFMAEHLEETLSAVTSNRQLKKDGDMTAFNKLVNTMKASGTLPTQPKVSRNLESHLLAPAEIPGQPVPKNILQELLGQPVQRPASSNLLSGLMGSLEPTASLLSQRAPSPPMSQVFRTQAASADYLHPRIPSPIGFPSGPQQLLGDPFQGMRKPMSPVTAQMSQLELQQAALEGLTLPHDLAVQTTPFYQPGFSKPQVDRTRDGLRNRQQRMTKSPAPMHRGNSSSPAPAASITSMLSPSFTPTSVIRKMYESREKSKEEIAPGTVVPGDGKEDAQKASEENLLSSNSISNSDQDSSPTANPKLSTLQRSSCSTPLSQTNRYTKEQDYRPKAAGRKTPTLASPVPGTPFLRPTHQVPLVPHVPIVRPAHQLHPGLVQRLIAQGVHPQHLPGLLQAGVLPPGIDIAPLQGLSGPLLGQPLYPLVSAASHPLLNPRPGTPLHLAVMQQQLQRSVLHPPGSSSQAAAINVQTPPNVPSRSGLPHMHSQLEHRTSQRSSSPVGLAKWFGSDVLQQPLPSMPTKVISVDELEYRQ", "length": 1004 }, "evidence": [ { "id": "A0A8V0ZTU2", "url": "https://omabrowser.org/oma/group/A0A8V0ZTU2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3I1Z5-1", "protein_name": "Eukaryotic translation initiation factor 4E transporter", "gene_name": "Eif4enif1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEKRGVDEIENGDAFLELKKLPTSKSPHRYTKEELLDIKERPYSKQRPSCLSEKYDSDGVWDPEKWHASLYPASGRSSPVESLKKEPESDRPSLVRRIADPRERVKEDDLDVVLSPQRRSFGGGCHVTAAVSSRRSGSPLEKDTDGLRLLGGRRIGSGRIISARAFEKDHRLSDKDLRDLRDRDRERDYKDKRFRREFGDSKRVFGERRRNDSYTEEEPEWFSAGPTSQSETIELTGFDDKILEEDHKGRKRTRRRTTSVKEGIVECNGGVAEEDEVEVILAQEPSADQEVPRDVVLPEQSPGEFDFNEFFNLDKVPCLASMIEDVLGEGSVSASRFSRWFSNPSRSGSRSSSLGSTPHEELERLAGLEQAVLSPGQNSGNYFAPIPSEDHAENKVDILEMLQKAKVDLKPLLSSLSANKEKLKESSHSGVVLSVEEVEAGLKGLKVDQQMKNSTPFMAEHLEETLSAVNSNRQLKKDGDMTAFNKLVSTMKASGTLPAQPKVSRNLENHLLAPAEIPGQPVPKNILQELLGQPVQRPASSNLLSGLMGSLEPTASLLSQRAPSPPMSQVFQTRAASADYLHPRIPSPIGFPSGPQQLLGDPFQGMRKPMSPVTAQMSQLELQQAALEGLALPHDLAVQAASFYQPGFNKPQVDRTRDGLRSRQQRVSKSPAPMHRGNSSSPAPAASITSMLSPSFTPTSVIRKMYESREKSKEEIAPGTVVPGDAKEDTQKASEETLLTSNPISNTDQDSSPTTNPKLSTLQRSSCSTPLSQNNRYTKEQDYRSKAAGRKTPTLATPVPGTPFLRPTHHVPLVPHVPIVRPAHQLHPGLVQRLIAQGVHPQHLPSLLQAGVLPPGIDMAPLQGISGPLLGQPLYPFSAASHPILNPRPGTPLHLAVMQQQLQRSVLHPPGSGSQAAPVNVQTPQNVPGRSGLPHMHSQLEHRTSQRSSSPVGLAKWFGSDVLQQPLPSMPTKVISVDELEYRQ", "length": 984 }, "evidence": [ { "id": "A0A8V0ZTU2", "url": "https://omabrowser.org/oma/group/A0A8V0ZTU2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q9EST3-1", "protein_name": "Eukaryotic translation initiation factor 4E transporter", "gene_name": "Eif4enif1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEKSVAETENGDAFLELKKLPTSKSPHRYTKEELLDIKERPYSKQRPSCLSEKYDSDGVWDPEKWHASLYPASGRSSPVESLKKESESDRPSLVRRIADPRERVKEDDLDVVLSPQRRSFGGGCHVTAAVSSRRSGSPLEKDSDGLRLLGGRRIGSGRIISARAFEKDHRLSDKDLRDLRDRDRERDYKDKRFRREFGDSKRVFGERRRNDSYTEEEPEWFSAGPTSQSETIELTGFDDKILEEDHKGRKRTRRRTASVKEGIVECNGGVAEEDEVEVILAQEPSADQEVPRDVILPEQSPGEFDFNEFFNLDKVPCLASMIEDVLGEGSVSASRFSRWFSNPSRSGSRSSSLGSTPHEELERLAGLEQAVLSPGQNSGNYFAPIPSEDHAENKVDILEMLQKAKVDLKPLLSSLSANKEKLKESSHSGVVLSVEEVEAGLKGLKVDQQMKNSTPFMAEHLEETLSAASSNRQLKKDGDMTAFNKLVNTMKASGTLPTQPKVSRNVESHLLAPAEIPGQPVSKNILQELLGQPVQRPASSNLLSGLMGSLEATASLLSQRAPSPPMSQVFRTQAASADYLHPRIPSPIGFPSGPQQLLGDPFQGMRKPMSPVSAQMSQLELQQAALEGLALPHDLAVQTAPFYQPGFSKPQVDRTRDGLRNRQQRMSKSPAPMHGGNSSSPAPAASITSMLSPSFTPTSVIRKMYESREKTKEEMAPGMVVPGDGKEDTQKTSEENLLSSNPIPNTDQDSSTTNPKLSTLQRSSCSTPLSQTSRYTKEQDYRPKTAGRKTPTLASPVPGTPFLRPTHQVPLVPHVPIVRPAHQLHPGLVQRLIAQGVHPQHLPSLLQAGVLPPGIDMAPLQGLSGPLLGQPLYPLVSAASHPLLNPRPGTPLHLAVMQQQLQRSVLHPPGSSSQAAAISVQTPQNVPSRSGMPHMHSQLEHRTSQRSSSPVGLAKWFGSDVLQQPLPSMPTKVISVDELEYRQ", "length": 983 }, "evidence": [ { "id": "A0A8V0ZTU2", "url": "https://omabrowser.org/oma/group/A0A8V0ZTU2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NRA8-1", "protein_name": "Eukaryotic translation initiation factor 4E transporter", "gene_name": "EIF4ENIF1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDRRSMGETESGDAFLDLKKPPASKCPHRYTKEELLDIKELPHSKQRPSCLSEKYDSDGVWDPEKWHASLYPASGRSSPVESLKKELDTDRPSLVRRIVDPRERVKEDDLDVVLSPQRRSFGGGCHVTAAVSSRRSGSPLEKDSDGLRLLGGRRIGSGRIISARTFEKDHRLSDKDLRDLRDRDRERDFKDKRFRREFGDSKRVFGERRRNDSYTEEEPEWFSAGPTSQSETIELTGFDDKILEEDHKGRKRTRRRTASVKEGIVECNGGVAEEDEVEVILAQEPAADQEVPRDAVLPEQSPGDFDFNEFFNLDKVPCLASMIEDVLGEGSVSASRFSRWFSNPSRSGSRSSSLGSTPHEELERLAGLEQAILSPGQNSGNYFAPIPLEDHAENKVDILEMLQKAKVDLKPLLSSLSANKEKLKESSHSGVVLSVEEVEAGLKGLKVDQQVKNSTPFMAEHLEETLSAVTNNRQLKKDGDMTAFNKLVSTMKASGTLPSQPKVSRNLESHLMSPAEIPGQPVPKNILQELLGQPVQRPASSNLLSGLMGSLEPTTSLLGQRAPSPPLSQVFQTRAASADYLRPRIPSPIGFTPGPQQLLGDPFQGMRKPMSPITAQMSQLELQQAALEGLALPHDLAVQAANFYQPGFGKPQVDRTRDGFRNRQQRVTKSPAPVHRGNSSSPAPAASITSMLSPSFTPTSVIRKMYESKEKSKEEPASGKAALGDSKEDTQKASEENLLSSSSVPSADRDSSPTTNSKLSALQRSSCSTPLSQANRYTKEQDYRPKATGRKTPTLASPVPTTPFLRPVHQVPLVPHVPMVRPAHQLHPGLVQRMLAQGVHPQHLPSLLQTGVLPPGMDLSHLQGISGPILGQPFYPLPAASHPLLNPRPGTPLHLAMVQQQLQRSVLHPPGSGSHAAAVSVQTTPQNVPSRSGLPHMHSQLEHRPSQRSSSPVGLAKWFGSDVLQQPLPSMPAKVISVDELEYRQ", "length": 985 }, "evidence": [ { "id": "A0A8V0ZTU2", "url": "https://omabrowser.org/oma/group/A0A8V0ZTU2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTU2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTU2" } ], "pmid": "" }, { "name": "kinase binding", "id": "GO:0019900", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019900", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTU2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTU2" } ], "pmid": "" }, { "name": "nuclear export signal receptor activity", "id": "GO:0005049", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005049", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTU2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTU2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTU2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTU2" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTU2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTU2" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTU2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTU2" } ], "pmid": "" }, { "name": "P-body", "id": "GO:0000932", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000932", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTU2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTU2" } ], "pmid": "" }, { "name": "cytoplasmic ribonucleoprotein granule", "id": "GO:0036464", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036464", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTU2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTU2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "mRNA stabilization", "id": "GO:0048255", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048255", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTU2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTU2" } ], "pmid": "" }, { "name": "negative regulation of translation", "id": "GO:0017148", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017148", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTU2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTU2" } ], "pmid": "" }, { "name": "positive regulation of nuclear-transcribed mRNA poly(A) tail shortening", "id": "GO:0060213", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060213", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTU2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTU2" } ], "pmid": "" }, { "name": "P-body assembly", "id": "GO:0033962", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033962", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTU2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTU2" } ], "pmid": "" }, { "name": "protein import into nucleus", "id": "GO:0006606", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006606", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTU2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTU2" } ], "pmid": "" }, { "name": "negative regulation of deadenylation-dependent decapping of nuclear-transcribed mRNA", "id": "GO:0106289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106289", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTU2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTU2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 234, "end_pos": 236, "annotation": "n_glycosylation_sequon" }, { "start_pos": 305, "end_pos": 307, "annotation": "n_glycosylation_sequon" }, { "start_pos": 40, "end_pos": 42, "annotation": "n_glycosylation_sequon" }, { "start_pos": 526, "end_pos": 528, "annotation": "n_glycosylation_sequon" }, { "start_pos": 700, "end_pos": 702, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 250, 707 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 234, "end_pos": 236 }, { "start_pos": 305, "end_pos": 307 }, { "start_pos": 40, "end_pos": 42 }, { "start_pos": 526, "end_pos": 528 }, { "start_pos": 700, "end_pos": 702 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZTU3-1", "uniprot_ac": "A0A8V0ZTU3", "uniprot_id": "A0A8V0ZTU3_CHICK", "mass": { "chemical_mass": 24512.0, "monoisotopic_mass": 24512.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "A0A8V0ZTU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTU3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTU3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTU3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTU3", "locus": {} } ], "crossref": [ { "id": "A0A8V0ZTU3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZTU3", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003591", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003591", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050216", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050216", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR48051", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48051", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR48051:SF55", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48051:SF55", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00560", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00560", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13855", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13855", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZTU3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTU3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZTU3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTU3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPGQEQDCLREVTLSTQRLRVLPPAVLSNPALESLDLDRNKLRSITGISKLGNLKKLIISKNEIVDFPTEIQSLIYLEKLELNQNQIRVIPEGIFCHLPRLKHLRLNNNRLGALPRDLAACRGSLQYLNISNNLFRTFPQPVLQLANLQELHVQNNALPGVLHDAPRVHHATGTRHPCHQPPHVRAEFRGEWEKENVSEVGDLSPSVSTVDAISIAPR", "length": 218, "header": "tr|A0A8V0ZTU3-1|A0A8V0ZTU3_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0ZTU3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZTU3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTU3/entry#A0A8V0ZTU3-1", "sequence": { "sequence": "MPGQEQDCLREVTLSTQRLRVLPPAVLSNPALESLDLDRNKLRSITGISKLGNLKKLIISKNEIVDFPTEIQSLIYLEKLELNQNQIRVIPEGIFCHLPRLKHLRLNNNRLGALPRDLAACRGSLQYLNISNNLFRTFPQPVLQLANLQELHVQNNALPGVLHDAPRVHHATGTRHPCHQPPHVRAEFRGEWEKENVSEVGDLSPSVSTVDAISIAPR", "length": 218, "header": "tr|A0A8V0ZTU3-1|A0A8V0ZTU3_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0ZTU3-1" }, "locus": { "chromosome": "5", "start_pos": 15452028, "end_pos": 15451040, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056042.1", "url": "https://www.ensembl.org/id/ENSGALT00010056042.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033906.1", "url": "https://www.ensembl.org/id/ENSGALP00010033906.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 129, "end_pos": 131, "annotation": "n_glycosylation_sequon" }, { "start_pos": 196, "end_pos": 198, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 129, "end_pos": 131 }, { "start_pos": 196, "end_pos": 198 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZTU5-1", "uniprot_ac": "A0A8V0ZTU5", "uniprot_id": "A0A8V0ZTU5_CHICK", "mass": { "chemical_mass": 147085.0, "monoisotopic_mass": 147085.0 }, "refseq": { "ac": "XP_015142122", "name": "pleckstrin homology domain-containing family A member 7 isoform X4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015142122" }, "gene_names": [ { "name": "PLEKHA7", "type": "recommended", "evidence": [ { "id": "A0A8V0ZTU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTU5" } ] }, { "name": "PLEKHA7", "type": "synonym", "evidence": [ { "id": "XP_015142122", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015142122" } ] } ], "protein_names": [ { "name": "Pleckstrin homology domain-containing family A member 7", "type": "recommended", "evidence": [ { "id": "A0A8V0ZTU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTU5/entry#names_and_taxonomy" } ] }, { "name": "pleckstrin homology domain-containing family A member 7 isoform X4", "type": "synonym", "evidence": [ { "id": "XP_015142122", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015142122" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052536.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015142122", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015142122" } ] }, { "annotation": "Required for zonula adherens biogenesis and maintenance. Acts via its interaction with CAMSAP3, which anchors microtubules at their minus-ends to zonula adherens, leading to the recruitment of KIFC3 kinesin to the junctional site. Mediates docking of ADAM10 to zonula adherens through a PDZD11-dependent interaction with the ADAM10-binding protein TSPAN33.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTU5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTU5#function" }, { "database": "UniProtKB", "id": "ARBA00058388", "url": "https://www.uniprot.org/uniprotkb/ARBA00058388#function" }, { "database": "UniProtKB", "id": "A0A8V0ZRV1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRV1#function" }, { "database": "UniProtKB", "id": "A0A8V0ZTV0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTV0#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTU5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTU5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PLEKHA7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTU5", "locus": { "chromosome": "5", "start_pos": 11190039, "end_pos": 11330666, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010023181", "url": "https://www.ensembl.org/id/ENSGALG00010023181" } ] } } ], "crossref": [ { "id": "ENSGALG00000029679", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000029679", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00201", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00201", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd13248", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13248", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "423069", "url": "https://www.ncbi.nlm.nih.gov/gene/423069", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001202", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001202", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036020", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036020", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040392", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040392", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057971", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057971", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PWH3", "url": "https://www.orthodb.org/?gene=A0A1D5PWH3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZLK3", "url": "https://www.orthodb.org/?gene=A0A8V0ZLK3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZRT7", "url": "https://www.orthodb.org/?gene=A0A8V0ZRT7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZRV1", "url": "https://www.orthodb.org/?gene=A0A8V0ZRV1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZTU5", "url": "https://www.orthodb.org/?gene=A0A8V0ZTU5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZTV0", "url": "https://www.orthodb.org/?gene=A0A8V0ZTV0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12752", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12752", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12752:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12752:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00169", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00169", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25541", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25541", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015142122", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015142122", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PWH3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PWH3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PWH3-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PWH3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLK3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLK3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLK3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLK3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRT7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRT7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRT7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRT7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRV1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRV1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRV1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRV1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZTU5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTU5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZTU5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTU5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZTV0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTV0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZTV0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTV0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAAVGRDALPEHWSYGVCRDGRVFFIDDLTRSTTWLHPRTGEPVNSGHMIRSDLPRGWEEGFSEEGASYFIDHNQQTTSFRHPVTGQVSPENIEFILQEEQNSPMSNQQINQRPSSMVSESSTAVTMSAVDTKPGSKVMKAGNKVHSFGKREQAIRRNPNVPVIVRGWLHKQDSSGMRLWKRRWFVLADYCLFYYKDSREESVLGSIPLPSYVISPVGPEDRINRKFSFKAVHTGMRAYIYNKNSVIGSQAEHSGMRTYYFSADTQEDMNSWIRAMNQAALMQTRSSLRRETEKADQRAVPQVNHVDACKVCVKAEATDTKESYQKSAEMLGYDKREEIRREKEEEERYIHRKEALETKKGKAKHALTEADSLFPDLTNAPRSQVAQSLPIEKNGTLPSSLSMSAGLAEQNGTSSYKRGFVPRTNPDKQIQRKSNMAQVEHWVKVQKGDTKSLASDLTLTRQGPNPPFSENYHTLPKNTRQPSGSSPPPLSRNLPSDYKYAQDRVSHLKMSQEERKANKDGTVWQLYEWQQRQQFKHGSPTAPLYVGSSDFIDRGKSKSSLDVPRSISVPPSPSDIPPPGPPKSFLPRRPHTPAERLTVKPSDERQTVDSPFAGSPRKIRSNALKSSTHIDRRSMPSMGYMTHTVSAPSLHGKSADDTYIQLKKDLEYLDLKVSGRDTLKERSTKPVKVAESDIDVKLSVFCEQDRILQDLEDKIRALKENKDQLESVLEVLHRQMEQYKDQPQHAEKISYQQRLLQEDLIHIRAEISKVSTEMENAWKEYLKLENDVSQLKKALQEQMNSSLVSQEKTQIQKDLWRIEDVTAGLSANKANYKTIVDSIKNPERKTVPSFSQSTVPSLPASLTTVESKPSVPQSPPSSLVKPSLEVRLYPQPYFQSRTQQQVPQLKKIEPPLQSPVRLTPKVEDEAPPRPPLPQLYSPEDQPPAVPPLPREATVIRHTSVRGLKRQSDERKRDRELGQYVNGDYRVELRSYVSEPELAMIGGDLSQPSSGFITVDSGYQTLPTRGLSGSTSRLHQSSTISSYATLRRDRSKERPKSALERLYSGDHQRGKMSAEEQLERMKRHQKALVRERKRTLSQGERQSVSSRSFIRPISADIGSWKREQEFDLQLLERAIRGEEKDENEWLKVQPVAVAVTETDLEPQDYDLDISRELSKPEKVAIPERYVELEPEEPLSTEELAARQRKAEKIKNILTKSSMHNLQPTIAQDKHNSVDLDSQLQEQERIITISYALASEASQRSKEVAAQQLTYPPKAPSPSVPQPPHSPLSNGFHYTFV", "length": 1296, "header": "tr|A0A8V0ZTU5-1|A0A8V0ZTU5_CHICK Isoform 1 of Pleckstrin homology domain-containing family A member 7 OS=Gallus gallus OX=9031 GN=PLEKHA7 PE=1 SV=1 CANONICAL=A0A8V0ZTU5-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PWH3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTU5/entry#A0A1D5PWH3-1", "sequence": { "sequence": "MSNQQINQRPSSMVSESSTAVTMSAVDTKPGSKVMKAGNKVHSFGKREQAIRRNPNVPVIVRGWLHKQDSSGMRLWKRRWFVLADYCLFYYKDSREESVLGSIPLPSYVISPVGPEDRINRKFSFKAVHTGMRAYIYNKNSVIGSQAEHSGMRTYYFSADTQEDMNSWIRAMNQAALMQTRSSLRRETEKADQRAVPQVNHVDACKVCVKAEATDTKESYQKSAEMLGYDKREEIRREKEEEERYIHRKEALETKKGKAKHALTEADSLFPDLTNAPRSQVAQSLPIEKNGTLPSSLSMSAGLAEQNGTSSYKRGFVPRTNPDKQIQRKSNMAQVEHWVKVQKGDTKSLASDLTLTRQGPNPPFSENYHTLPKNTRQPSGSSPPPLSRNLPSDYKYAQDRVSHLKMSQEERKANKDGTVWQLYEWQQRQQFKHGSPTAPLYVGSSDFIDRGKSKSSLDVPRSISVPPSPSDIPPPGPPKSFLPRRPHTPAERLTVKPSDERQTVDSPFAGSPRKIRSNALKSSTHIDRRSMPSMGYMTHTVSAPSLHGKSADDTYIQLKKDLEYLDLKVSGRDTLKERSTKPVKVAESDIDVKLSVFCEQDRILQDLEDKIRALKENKDQLESVLEVLHRQMEQYKDQPQHAEKISYQQRLLQEDLIHIRAEISKVSTEMENAWKEYLKLENDVSQLKKALQEQMNSSLVSQEKTQIQKDLWRIEDVTAGLSANKANYKTIVDSIKNPERKTVPSFSQSTVPSLPASLTTVESKPSVPQSPPSSLVKPSLEVRLYPQPYFQSRTQQQVPQLKKIEPPLQSPVRLTPKVEDEAPPRPPLPQLYSPEDQPPAVPPLPREATVIRHTSVRGLKRQSDERKRDRELGQYVNGDYRVELRSYVSEPELAMIGGDLSQPSSGFITVDSGYQTLPTRGLSGSTSRLHQSSTISSYATLRRDRSKERPKSALERLYSGDHQRGKMSAEEQLERMKRHQKALVRERKRTLSQGERQSVSSRSFIRPISADIGSWKREQEFDLQLLERAIRGEEKDENEWLKVQPVAVAVTETDLEPQDYDLDISRELSKPEKVAIPERYVELEPEEPLSTEELAARQRKAEKIKNILTKSSMHNLQPTIAQDKHNSVDLDSQLQEQERIITISYALASEASQRSKEVAAKAVSEH", "length": 1166, "header": "tr|A0A1D5PWH3-1|A0A1D5PWH3_CHICK Computationally mapped isoform of Pleckstrin homology domain containing A7 OS=Gallus gallus OX=9031 GN=PLEKHA7 PE=1 SV=3 CANONICAL=A0A8V0ZTU5-1" }, "locus": { "chromosome": "5", "start_pos": 11245781, "end_pos": 11191548, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056503.1", "url": "https://www.ensembl.org/id/ENSGALT00010056503.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034246.1", "url": "https://www.ensembl.org/id/ENSGALP00010034246.1" } ] } }, { "isoform_ac": "A0A8V0ZLK3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTU5/entry#A0A8V0ZLK3-1", "sequence": { "sequence": "MQTAEEVLGSSQGRRERGWCCLDCRVPSRRAGWELCTGRLPRAVWFHGVYEEEHCVRSLAGGHNQQTTSFRHPVTGQVSPENIEFILQEEQNSPMSNQQINQRPSSMVSESSTAVTMSAVDTKPGSKVMKAGNKVHSFGKREQAIRRNPNVPVIVRGWLHKQDSSGMRLWKRRWFVLADYCLFYYKDSREESVLGSIPLPSYVISPVGPEDRINRKFSFKAVHTGMRAYIYNKNSVIGSQAEHSGMRTYYFSADTQEDMNSWIRAMNQAALMQTRSSLRRETEKADQRAVPQVNHVDACKVCVKAEATDTKESYQKSAEMLGYDKREEIRREKEEEERYIHRKEALETKKGKAKHALTEADSLFPDLTNAPRSQVAQSLPIEKNGTLPSSLSMSAGLAEQNGTSSYKRGFVPRTNPDKQIQRKSNMAQVEHWVKVQKGDTKSLASDLTLTRQGPNPPFSENYHTLPKNTRQPSGSSPPPLSRNLPSDYKYAQDRVSHLKMSQEERKANKDGTVWQLYEWQQRQQFKHGSPTAPLYVGSSDFIDRGKSKSSLDVPRSISVPPSPSDIPPPGPPKSFLPRRPHTPAERLTVKPSDERQTVDSPFAGSPRKIRSNALKSSTHIDRRSMPSMGYMTHTVSAPSLHGKSADDTYIQLKKDLEYLDLKVSGRDTLKERSTKPVKVAESDIDVKLSVFCEQDRILQDLEDKIRALKENKDQLESVLEVLHRQMEQYKDQPQHAEKISYQQRLLQEDLIHIRAEISKVSTEMENAWKEYLKLENDVSQLKKALQEQMNSSLVSQEKTQIQKDLWRIEDVTAGLSANKANYKTIVDSIKNPERKTVPSFSQSTVPSLPASLTTVESKPSVPQSPPSSLVKPSLEVRLYPQPYFQSRTQQQVPQLKKIEPPLQSPVRLTPKVEDEAPPRPPLPQLYSPEDQPPAVPPLPREATVIRHTSVRGLKRQSDERKRDRELGQYVNGDYRVELRSYVSEPELAMIGGDLSQPSSGFITVDSGYQTLPTRGLSGSTSRLHQSSTISSYATLRRDRSKERPKSALERLYSGDHQRGKMSAEEQLERMKRHQKALVRERKRTLSQGERQSVSSRSFIRPISADIGSWKREQEFDLQLLERAIRGEEKDENEWLKVQPVAVAVTETDLEPQDYDLDISRELSKPEKVAIPERYVELEPEEPLSTEELAARQRKAEKIKNILTKSRSVIF", "length": 1210, "header": "tr|A0A8V0ZLK3-1|A0A8V0ZLK3_CHICK Computationally mapped isoform of Pleckstrin homology domain containing A7 OS=Gallus gallus OX=9031 GN=PLEKHA7 PE=1 SV=1 CANONICAL=A0A8V0ZTU5-1" }, "locus": { "chromosome": "5", "start_pos": 11326299, "end_pos": 11197071, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056507.1", "url": "https://www.ensembl.org/id/ENSGALT00010056507.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034250.1", "url": "https://www.ensembl.org/id/ENSGALP00010034250.1" } ] } }, { "isoform_ac": "A0A8V0ZRT7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTU5/entry#A0A8V0ZRT7-1", "sequence": { "sequence": "MSSQSGFSNSVPLPGYPFYQVPCSHNQQTTSFRHPVTGQVSPENIEFILQEEQNSPMSNQQINQRPSSMVSESSTAVTMSAVDTKPGSKVMKAGNKVHSFGKREQAIRRNPNVPVIVRGWLHKQDSSGMRLWKRRWFVLADYCLFYYKDSREESVLGSIPLPSYVISPVGPEDRINRKFSFKAVHTGMRAYIYNKNSVIGSQAEHSGMRTYYFSADTQEDMNSWIRAMNQAALMQTRSSLRRETEKADQRAVPQVNHVDACKVCVKAEATDTKESYQKSAEMLGYDKREEIRREKEEEERYIHRKEALETKKGKAKHALTEADSLFPDLTNAPRSQVAQSLPIEKNGTLPSSLSMSAGLAEQNGTSSYKRGFVPRTNPDKQIQRKSNMAQVEHWVKVQKGDTKSLASDLTLTRQGPNPPFSENYHTLPKNTRQPSGSSPPPLSRNLPSDYKYAQDRVSHLKMSQEERKANKDGTVWQLYEWQQRQQFKHGSPTAPLYVGSSDFIDRGKSKSSLDVPRSISVPPSPSDIPPPGPPKSFLPRRPHTPAERLTVKPSDERQTVDSPFAGSPRKIRSNALKSSTHIDRRSMPSMGYMTHTVSAPSLHGKSADDTYIQLKKDLEYLDLKVSGRDTLKERSTKPVKVAESDIDVKLSVFCEQDRILQDLEDKIRALKENKDQLESVLEVLHRQMEQYKDQPQHAEKISYQQRLLQEDLIHIRAEISKVSTEMENAWKEYLKLENDVSQLKKALQEQMNSSLVSQEKTQIQKDLWRIEDVTAGLSANKANYKTIVDSIKNPERKTVPSFSQSTVPSLPASLTTVESKPSVPQSPPSSLVKPSLEVRLYPQPYFQSRTQQQVPQLKKIEPPLQSPVRLTPKVEDEAPPRPPLPQLYSPEDQPPAVPPLPREATVIRHTSVRGLKRQSDERKRDRELGQYVNGDYRVELRSYVSEPELAMIGGDLSQPSSGFITVDSGYQTLPTRGLSGSTSRLHQSSTISSYATLRRDRSKERPKSALERLYSGDHQRGKMSAEEQLERMKRHQKALVRERKRTLSQGERQSVSSRSFIRPISADIGSWKREQEFDLQLLERAIRGEEKDENEWLKVQPVAVAVTETDLEPQDYDLDISRELSKPEKVAIPERYVELEPEEPLSTEELAARQRKAEKIKNILTKSSMHNLQPTIAQDKHNSVDLDSQLQEQERIITISYALASEASQRSKEVAAKAVSEH", "length": 1222, "header": "tr|A0A8V0ZRT7-1|A0A8V0ZRT7_CHICK Computationally mapped isoform of Pleckstrin homology domain containing A7 OS=Gallus gallus OX=9031 GN=PLEKHA7 PE=1 SV=1 CANONICAL=A0A8V0ZTU5-1" }, "locus": { "chromosome": "5", "start_pos": 11286495, "end_pos": 11191548, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056498.1", "url": "https://www.ensembl.org/id/ENSGALT00010056498.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034241.1", "url": "https://www.ensembl.org/id/ENSGALP00010034241.1" } ] } }, { "isoform_ac": "A0A8V0ZRV1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTU5/entry#A0A8V0ZRV1-1", "sequence": { "sequence": "MAAAVGRDALPEHWSYGVCRDGRVFFIDDLTRSTTWLHPRTGEPVNSGHMIRSDLPRGWEEGFSEEGASYFIEQNSPMSNQQINQRPSSMVSESSTAVTMSAVDTKPGSKVMKAGNKVHSFGKREQAIRRNPNVPVIVRGWLHKQDSSGMRLWKRRWFVLADYCLFYYKDSREESVLGSIPLPSYVISPVGPEDRINRKFSFKAVHTGMRAYIYNKNSVIGSQAEHSGMRTYYFSADTQEDMNSWIRAMNQAALMQTRSSLRRETEKADQRAVPQVNHVDACKVCVKAEATDTKESYQKSAEMLGYDKREEIRREKEEEERYIHRKEALETKKGKAKHALTEADSLFPDLTNAPRSQVAQSLPIEKNGTLPSSLSMSAGLAEQNGTSSYKRGFVPRTNPDKQIQRKSNMAQVEHWVKVQKGDTKSLASDLTLTRQGPNPPFSENYHTLPKNTRQPSGSSPPPLSRNLPSDYKYAQDRVSHLKMSQEERKANKDGTVWQLYEWQQRQQFKHGSPTAPLYVGSSDFIDRGKSKSSLDVPRSISVPPSPSDIPPPGPPKSFLPRRPHTPAERLTVKPSDERQTVDSPFAGSPRKIRSNALKSSTHIDRRSMPSMGYMTHTVSAPSLHGKSADDTYIQLKKDLEYLDLKVSGRDTLKERSTKPVKVAESDIDVKLSVFCEQDRILQDLEDKIRALKENKDQLESVLEVLHRQMEQYKDQPQHAEKISYQQRLLQEDLIHIRAEISKVSTEMENAWKEYLKLENDVSQLKKALQEQMNSSLVSQEKTQIQKDLWRIEDVTAGLSANKANYKTIVDSIKNPERKTVPSFSQSTVPSLPASLTTVESKPSVPQSPPSSLVKPSLEVRLYPQPYFQSRTQQQVPQLKKIEPPLQSPVRLTPKVEDEAPPRPPLPQLYSPEDQPPAVPPLPREATVIRHTSVRGLKRQSDERKRDRELGQYVNGDYRVELRSYVSEPELAMIGGDLSQPSSGFITVDSGYQTLPTRGLSGSTSRLHQSSTISSYATLRRDRSKERPKSALERLYSGDHQRGKMSAEEQLERMKRHQKALVRERKRTLSQGERQSVSSRSFIRPISADIGSWKREQEFDLQLLERAIRGEEKDENEWLKVQPVAVAVTETDLEPQDYDLDISRELSKPEKVAIPERYVELEPEEPLSTEELAARQRKAEKIKNILTKSSMHNLQPTIAQDKHNSVDLDSQLQEQERIITISYALASEASQRSKEVAAKAVSEH", "length": 1243, "header": "tr|A0A8V0ZRV1-1|A0A8V0ZRV1_CHICK Computationally mapped isoform of Pleckstrin homology domain-containing family A member 7 OS=Gallus gallus OX=9031 GN=PLEKHA7 PE=1 SV=1 CANONICAL=A0A8V0ZTU5-1" }, "locus": { "chromosome": "5", "start_pos": 11330608, "end_pos": 11191548, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056516.1", "url": "https://www.ensembl.org/id/ENSGALT00010056516.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034258.1", "url": "https://www.ensembl.org/id/ENSGALP00010034258.1" } ] } }, { "isoform_ac": "A0A8V0ZTU5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTU5/entry#A0A8V0ZTU5-1", "sequence": { "sequence": "MAAAVGRDALPEHWSYGVCRDGRVFFIDDLTRSTTWLHPRTGEPVNSGHMIRSDLPRGWEEGFSEEGASYFIDHNQQTTSFRHPVTGQVSPENIEFILQEEQNSPMSNQQINQRPSSMVSESSTAVTMSAVDTKPGSKVMKAGNKVHSFGKREQAIRRNPNVPVIVRGWLHKQDSSGMRLWKRRWFVLADYCLFYYKDSREESVLGSIPLPSYVISPVGPEDRINRKFSFKAVHTGMRAYIYNKNSVIGSQAEHSGMRTYYFSADTQEDMNSWIRAMNQAALMQTRSSLRRETEKADQRAVPQVNHVDACKVCVKAEATDTKESYQKSAEMLGYDKREEIRREKEEEERYIHRKEALETKKGKAKHALTEADSLFPDLTNAPRSQVAQSLPIEKNGTLPSSLSMSAGLAEQNGTSSYKRGFVPRTNPDKQIQRKSNMAQVEHWVKVQKGDTKSLASDLTLTRQGPNPPFSENYHTLPKNTRQPSGSSPPPLSRNLPSDYKYAQDRVSHLKMSQEERKANKDGTVWQLYEWQQRQQFKHGSPTAPLYVGSSDFIDRGKSKSSLDVPRSISVPPSPSDIPPPGPPKSFLPRRPHTPAERLTVKPSDERQTVDSPFAGSPRKIRSNALKSSTHIDRRSMPSMGYMTHTVSAPSLHGKSADDTYIQLKKDLEYLDLKVSGRDTLKERSTKPVKVAESDIDVKLSVFCEQDRILQDLEDKIRALKENKDQLESVLEVLHRQMEQYKDQPQHAEKISYQQRLLQEDLIHIRAEISKVSTEMENAWKEYLKLENDVSQLKKALQEQMNSSLVSQEKTQIQKDLWRIEDVTAGLSANKANYKTIVDSIKNPERKTVPSFSQSTVPSLPASLTTVESKPSVPQSPPSSLVKPSLEVRLYPQPYFQSRTQQQVPQLKKIEPPLQSPVRLTPKVEDEAPPRPPLPQLYSPEDQPPAVPPLPREATVIRHTSVRGLKRQSDERKRDRELGQYVNGDYRVELRSYVSEPELAMIGGDLSQPSSGFITVDSGYQTLPTRGLSGSTSRLHQSSTISSYATLRRDRSKERPKSALERLYSGDHQRGKMSAEEQLERMKRHQKALVRERKRTLSQGERQSVSSRSFIRPISADIGSWKREQEFDLQLLERAIRGEEKDENEWLKVQPVAVAVTETDLEPQDYDLDISRELSKPEKVAIPERYVELEPEEPLSTEELAARQRKAEKIKNILTKSSMHNLQPTIAQDKHNSVDLDSQLQEQERIITISYALASEASQRSKEVAAQQLTYPPKAPSPSVPQPPHSPLSNGFHYTFV", "length": 1296, "header": "tr|A0A8V0ZTU5-1|A0A8V0ZTU5_CHICK Isoform 1 of Pleckstrin homology domain-containing family A member 7 OS=Gallus gallus OX=9031 GN=PLEKHA7 PE=1 SV=1 CANONICAL=A0A8V0ZTU5-1" }, "locus": { "chromosome": "5", "start_pos": 11330608, "end_pos": 11193141, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056512.1", "url": "https://www.ensembl.org/id/ENSGALT00010056512.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034254.1", "url": "https://www.ensembl.org/id/ENSGALP00010034254.1" } ] } }, { "isoform_ac": "A0A8V0ZTV0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTU5/entry#A0A8V0ZTV0-1", "sequence": { "sequence": "MAAAVGRDALPEHWSYGVCRDGRVFFIDDLTRSTTWLHPRTGEPVNSGHMIRSDLPRGWEEGFSEEGASYFIDHNQQTTSFRHPVTGQVSPENIEFILQEEQNSPMSNQQINQRPSSMVSESSTAVTMSAVDTKPGSKVMKAGNKVHSFGKREQAIRRNPNVPVIVRGWLHKQDSSGMRLWKRRWFVLADYCLFYYKDSREESVLGSIPLPSYVISPVGPEDRINRKFSFKAVHTGMRAYIYNKNSVIGSQAEHSGMRTYYFSADTQEDMNSWIRAMNQAALMQTRSSLRRETEKADQRAVPQVNHVDACKVCVKAEATDTKESYQKSAEMLGYDKREEIRREKEEEERYIHRKEALETKKGKAKHALTEADSLFPDLTNAPRSQVAQSLPIEKNGTLPSSLSMSAGLAEQNGTSSYKRGFVPRTNPDKQIQRKSNMAQVEHWVKVQKGDTKSLASDLTLTRQGPNPPFSENYHTLPKNTRQPSGSSPPPLSRNLPSDYKYAQDRVSHLKMSQEERKANKDGTVWQLYEWQQRQQFKHGSPTAPLYVGSSDFIDRGKSKSSLDVPRSISVPPSPSDIPPPGPPKSFLPRRPHTPAERLTVKPSDERQTVDSPFAGSPRKIRSNALKSSTHIDRRSMPSMGYMTHTVSAPSLHGKSADDTYIQLKKDLEYLDLKVSGRDTLKERSTKPVKVAESDIDVKLSVFCEQDRILQDLEDKIRALKENKDQLESVLEVLHRQMEQYKDQPQHAEKISYQQRLLQEDLIHIRAEISKVSTEMENAWKEYLKLENDVSQLKKALQEQMNSSLVSQEKTQIQKDLWRIEDVTAGLSANKANYKTIVDSIKNPERKTVPSFSQSTVPSLPASLTTVESKPSVPQSPPSSLVKPSLEVRLYPQPYFQSRTQQQVPQLKKIEPPLQSPVRLTPKVEDEAPPRPPLPQLYSPEDQPPAVPPLPREATVIRHTSVRGLKRQSDERKRDRELGQYVNGDYRVELRSYVSEPELAMIGGDLSQPSSGFITVDSGYQTLPTRGLSGSTSRLHQSSTISSYATLRRDRSKERPKSALERLYSGDHQRGKMSAEEQLERMKRHQKALVRERKRTLSQGERQSVSSRSFIRPISADIGSWKREQEFDLQLLERAIRGEEKDENEWLKVQPVAVAVTETDLEPQDYDLDISRELSKPEKVAIPERYVELEPEEPLSTEELAARQRKAEKIKNILTKSSMHNLQPTIAQDKHNSVDLDSQLQEQERIITISYALASEASQRSKEVAAKAVSEH", "length": 1271, "header": "tr|A0A8V0ZTV0-1|A0A8V0ZTV0_CHICK Computationally mapped isoform of Pleckstrin homology domain-containing family A member 7 OS=Gallus gallus OX=9031 GN=PLEKHA7 PE=1 SV=1 CANONICAL=A0A8V0ZTU5-1" }, "locus": { "chromosome": "5", "start_pos": 11330608, "end_pos": 11191548, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056518.1", "url": "https://www.ensembl.org/id/ENSGALT00010056518.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034260.1", "url": "https://www.ensembl.org/id/ENSGALP00010034260.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 8, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTU5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTU5" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTU5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTU5" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTU5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTU5" } ], "pmid": "" }, { "name": "pore complex", "id": "GO:0046930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046930", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTU5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTU5" } ], "pmid": "" }, { "name": "zonula adherens", "id": "GO:0005915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005915", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTU5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTU5" } ], "pmid": "" }, { "name": "adherens junction", "id": "GO:0005912", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005912", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTU5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTU5" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTU5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTU5" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTU5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTU5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "pore complex assembly", "id": "GO:0046931", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046931", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTU5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTU5" } ], "pmid": "" }, { "name": "cell-cell adhesion mediated by cadherin", "id": "GO:0044331", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044331", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTU5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTU5" } ], "pmid": "" }, { "name": "zonula adherens maintenance", "id": "GO:0045218", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045218", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTU5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTU5" } ], "pmid": "" }, { "name": "epithelial cell-cell adhesion", "id": "GO:0090136", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090136", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTU5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTU5" } ], "pmid": "" }, { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTU5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTU5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 395, "end_pos": 397, "annotation": "n_glycosylation_sequon" }, { "start_pos": 412, "end_pos": 414, "annotation": "n_glycosylation_sequon" }, { "start_pos": 801, "end_pos": 803, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZTU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTU5" }, { "id": "PS50003", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50003" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PH", "eco_id": "ECO_0000259", "start_pos": 163, "end_pos": 282, "start_aa": "Pro", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZTU5", "database": 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"id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR44337", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44337", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR44337:SF23", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44337:SF23", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13895", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13895", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13927", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13927", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZTV8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTV8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZTV8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTV8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLRVLVPVSKPFVRLTAAAAAEGTEVALTCTVREGTAPLSFSWQHREPHGGLLAAPTGLGGSGAELLLAPANRSHAGWYACTARNEVNNRTSEPVYLDIVYGPDEPAISVEPFSPEQGSFSAGEREDVVLSCLAPSNPPSRYIWLHNGSQVHIGQTFVMSAIARGQAGTYTCLAENTHLQTRTQATIVLTVYSEPPFEALPAVTGAAVMGMLVATSMSLLAVHCIARHRDRLPRLHELLFRIAGPNAPQLAEDANVAMSTEDGEGQGQEEPGGPSTAAMEEEPRSAPPGDPADDAPVDVTITMTAMP", "length": 307, "header": "tr|A0A8V0ZTV8-1|A0A8V0ZTV8_CHICK Isoform 1 of Ig-like domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0ZTV8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZTV8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTV8/entry#A0A8V0ZTV8-1", "sequence": { "sequence": "MLRVLVPVSKPFVRLTAAAAAEGTEVALTCTVREGTAPLSFSWQHREPHGGLLAAPTGLGGSGAELLLAPANRSHAGWYACTARNEVNNRTSEPVYLDIVYGPDEPAISVEPFSPEQGSFSAGEREDVVLSCLAPSNPPSRYIWLHNGSQVHIGQTFVMSAIARGQAGTYTCLAENTHLQTRTQATIVLTVYSEPPFEALPAVTGAAVMGMLVATSMSLLAVHCIARHRDRLPRLHELLFRIAGPNAPQLAEDANVAMSTEDGEGQGQEEPGGPSTAAMEEEPRSAPPGDPADDAPVDVTITMTAMP", "length": 307, "header": "tr|A0A8V0ZTV8-1|A0A8V0ZTV8_CHICK Isoform 1 of Ig-like domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0ZTV8-1" }, "locus": { "chromosome": "24", "start_pos": 379137, "end_pos": 375146, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010060205.1", "url": "https://www.ensembl.org/id/ENSGALT00010060205.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036965.1", "url": "https://www.ensembl.org/id/ENSGALP00010036965.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 147, "end_pos": 149, "annotation": "n_glycosylation_sequon" }, { "start_pos": 72, "end_pos": 74, "annotation": "n_glycosylation_sequon" }, { "start_pos": 89, "end_pos": 91, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZTV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTV8" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 11, "end_pos": 98, "start_aa": "Pro", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 147, "end_pos": 149 }, { "start_pos": 72, "end_pos": 74 }, { "start_pos": 89, "end_pos": 91 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZTX0-1", "uniprot_ac": "A0A8V0ZTX0", "uniprot_id": "A0A8V0ZTX0_CHICK", "mass": { "chemical_mass": 92265.0, "monoisotopic_mass": 92265.0 }, "refseq": { "ac": "NP_001265022", "name": "zinc finger protein 341", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001265022" }, "gene_names": [ { "name": "ZNF341", "type": "recommended", "evidence": [ { "id": "A0A8V0ZTX0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTX0" } ] }, { "name": "ZNF341", "type": "synonym", "evidence": [ { "id": "NP_001265022", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001265022" } ] } ], "protein_names": [ { "name": "Zinc finger protein 341", "type": "synonym", "evidence": [ { "id": "A0A8V0ZTX0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTX0/entry#names_and_taxonomy" } ] }, { "name": "zinc finger protein 341", "type": "synonym", "evidence": [ { "id": "NP_001265022", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001265022" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR13267649.211773.1, SRR13267659.257190.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992533, SAMN02738221 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000328.1. On or before Oct 25, 2021 this sequence version replaced XP_015151835.2, NP_001265022.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001265022", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001265022" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTX0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTX0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ZNF341", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTX0", "locus": { "chromosome": "20", "start_pos": 2485570, "end_pos": 2505241, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022030", "url": "https://www.ensembl.org/id/ENSGALG00010022030" } ] } } ], "crossref": [ { "id": "A0A8V0ZTX0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZTX0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000002968", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000002968", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "419152", "url": "https://www.ncbi.nlm.nih.gov/gene/419152", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039149", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039149", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:419152", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419152", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DGPCAML", "url": "https://omabrowser.org/oma/group/DGPCAML/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5P133", "url": "https://www.orthodb.org/?gene=A0A1D5P133", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A1L1RP19", "url": "https://www.orthodb.org/?gene=A0A1L1RP19", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2TXA2", "url": "https://www.orthodb.org/?gene=A0A3Q2TXA2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZLG0", "url": "https://www.orthodb.org/?gene=A0A8V0ZLG0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZTX0", "url": "https://www.orthodb.org/?gene=A0A8V0ZTX0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21020", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21020", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21020:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21020:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24376", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24376", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24376:SF243", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24376:SF243", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24408", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24408", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24408:SF58", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24408:SF58", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13912", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13912", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001265022", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001265022", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5P133", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P133", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5P133-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P133-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1L1RP19", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RP19", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1L1RP19-1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RP19-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2TXA2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TXA2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2TXA2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TXA2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLG0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLG0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLG0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLG0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZTX0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTX0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZTX0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTX0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAQAIFEALEGMDNQTVLAVQSLLDGQGGVTDPSAQNVNAAAPMQPMDDEDVFLCGKCKKQFNSLPAFMTHKREQCQGNAPSLSTVSLATNSVYTPSITSVQQAPSTSRQQISTYITVPPSPLIQTLVQGNILVSDEVLMSAMSAFTSLDQPMPAVQPPVQSSLSMHAGAGYLSQPPPPPPPPPPPPPQPPPPPPPSLGAPGQPSTGSGVVEVYSAPAPMAANSSVEIQALGMQPYPAMEVPSQCVESPVYPSPPVYSPGKQGFKPKSASVPTPLTSAGGGNVVGFDSTSAVKSRRSKSESGLQEGKPKSPKLKCTYCDKAFTKNFDLQQHIRSHTGEKPFQCIVCGRAFAQKSNVKKHMQTHKVWPPGLGCTISRNSITVQVMALNPNQVEDEENTGLTQPSRNPAQPPQDMSPMDESDAGKLEAKQVVLIDSSYQCQFCPSKFNTYFQLKSHMTQHKNEQVYKCVVKSCAQTFQKLESFLDHIKSHQEELSYRCHLCSKDFPSLYELGVHQYSHSLLPQHSPKKDVAVYKCVKCVNKYSTPEALEHHLQTATHNFPCPHCQKVFPCERYLRRHIPTHGGGSKFKCQICKKFFRREHYLKLHAHIHSGEKPFKCSVCDAAFNRKDKLKRHMLIHEPFKKYKCPFSSHTGCNKEFNRPDKLKAHILSHSGMKIHKCQYCNKSFSRRAHMIEHQRSHTGNYKYRCPTCSKGFTRHKYMKDHKCRLGSPKDKDLQLRKPQKKRVVRGRKVGLSLPNQLALGELKDSVGGESPQEGVPNKEPFQESDAVLSIVVGGSGAADSDLVVPGQPSSIASNLSLAELQAASDGPCTMLAVPVYIQTTE", "length": 840, "header": "tr|A0A8V0ZTX0-1|A0A8V0ZTX0_CHICK Isoform 1 of Zinc finger protein 341 OS=Gallus gallus OX=9031 GN=ZNF341 PE=4 SV=1 CANONICAL=A0A8V0ZTX0-1" }, "isoforms": [ { "isoform_ac": "A0A1D5P133-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTX0/entry#A0A1D5P133-1", "sequence": { "sequence": "MAQAIFEALEGMDNQTVLAVQSLLDGQGGVTDPSAQNVNAAAPMQPMDDEDVFLCGKCKKQFNSLPAFMTHKREQCQGNAPSLSTVSLATNSVYTPSITSVQQAPSTSRQQISTYITVPPSPLIQTLVQGNILVSDEVLMSAMSAFTSLDQPMPAVQPPVQSSLSMHAGAGYLSQPPPPPPPPPPPPPQPPPPPPPSLGAPGQPSTGSGVVEVYSAPAPMAANSSVEIQALGMQPYPAMEVPSQCVESPVYPSPPVYSPGKQGFKPKSASVPTPLTSAGGGNVVGFDSTSAVKSRRSKSESGLQEGKPKSPKLKCTYCDKAFTKNFDLQQHIRSHTGEKPFQCIVCGRAFAQKSNVKKHMQTHKVWPPGLGCTISRNSITVQVMALNPNQVEDEENTGLTQPSRNPAQPPQDMSPMDESDAGKLEAKQVVLIDSSYQCQFCPSKFNTYFQLKSHMTQHKNEQVYKCVVKSCAQTFQKLESFLDHIKSHQEELSYRCHLCSKDFPSLYELGVHQYSHSLLPQHSPKKDVAVYKCVKCVNKYSTPEALEHHLQTATHNFPCPHCQKNSLGSPLVPSFG", "length": 576, "header": "tr|A0A1D5P133-1|A0A1D5P133_CHICK Computationally mapped isoform of Zinc finger protein 341 OS=Gallus gallus OX=9031 GN=ZNF341 PE=4 SV=2 CANONICAL=A0A8V0ZTX0-1" }, "locus": { "chromosome": "20", "start_pos": 2505143, "end_pos": 2489774, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053574.1", "url": "https://www.ensembl.org/id/ENSGALT00010053574.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032282.1", "url": "https://www.ensembl.org/id/ENSGALP00010032282.1" } ] } }, { "isoform_ac": "A0A1L1RP19-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTX0/entry#A0A1L1RP19-1", "sequence": { "sequence": "MAQAIFEALEGMDNQTVLAVQSLLDGQGGVTDPSAQNVNAAAPMQPMDDEDVFLCGKCKKQFNSLPAFMTHKREQCQGNAPSLSTVSLATNSVYTPSITSVQQAPSTSRQQISTYITVPPSPLIQTLVQGNILVSDEVLMSAMSAFTSLDQPMPAVQPPVQSSLSMHAGAGYLSQPPPPPPPPPPPPPQPPPPPPPSLGAPGQPSTGSGVVEVYSAPAPMAANSSVEIQALGMQPYPAMEVPSQCVESPVYPSPPVYSPGKQGFKPKSASVPTPLTSAGGGNVVGFDSTSAVKSRRSKSESGLQEGKPKSPKLKCTYCDKAFTKNFDLQQHIRSHTGEKPFQCIVCGRAFAQKSNVKKHMQTHKVWPPGLGCTISRNSITVQVMALNPNQVEDEENTGLTQPSRNPAQPPQDMSPMDESDAGKLEAKQVVLIDSSYQCQFCPSKFNTYFQLKSHMTQHKNEQVYKCVVKSCAQTFQKLESFLDHIKSHQEELSYRCHLCSKDFPSLYELGVHQYSHSLLPQHSPKKDVAVYKCVKCVNKYSTPEALEHHLQTATHNFPCPHCQKVFPCERYLRRHIPTHGGGSKFKCQICKKFFRREHYLKLHAHIHSGNVWFPFSLVPSTAPVGSGTQN", "length": 630, "header": "tr|A0A1L1RP19-1|A0A1L1RP19_CHICK Computationally mapped isoform of Zinc finger protein 341 OS=Gallus gallus OX=9031 GN=ZNF341 PE=4 SV=2 CANONICAL=A0A8V0ZTX0-1" }, "locus": { "chromosome": "20", "start_pos": 2505143, "end_pos": 2488410, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053578.1", "url": "https://www.ensembl.org/id/ENSGALT00010053578.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032283.1", "url": "https://www.ensembl.org/id/ENSGALP00010032283.1" } ] } }, { "isoform_ac": "A0A3Q2TXA2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTX0/entry#A0A3Q2TXA2-1", "sequence": { "sequence": "MAQAIFEALEGMDNQTVLAVQSLLDGQGGVTDPSAQNVNAAAPMQPMDDEDVFLCGKCKKQFNSLPAFMTHKREQCQGNAPSLSTVSLATNSVYTPSITSVQQAPSTSRQQISTYITVPPSPLIQTLVQGNILVSDEVLMSAMSAFTSLDQPMPAVQPPVQSSLSMHAGAGYLSQPPPPPPPPPPPPPQPPPPPPPSLGAPGQPSTGSGVVEVYSAPAPMAANSSVEIQALGMQPYPAMEVPSQCVESPVYPSPPVYSPGKQGFKPKSASVPTPLTSAGGGNVVGFDSTSAVKSRRSKSESGLQEGKPKSPKLKCTYCDKAFTKNFDLQQHIRSHTGEKPFQCIVCGRAFAQKSNVKKHMQTHKVWPPGLGCTISRNSITVQVMALNPNQVEDEENTGLTQPSRNPAQPPQDMSPMDESDAGKLEAKQVVLIDSSYQCQFCPSKFNTYFQLKSHMTQHKNEQVYKCVVKSCAQTFQKLESFLDHIKSHQEELSYRCHLCSKDFPSLYELGVHQYSHSLLPQHSPKKDVAVYKCVKCVNKYSTPEALEHHLQTATHNFPCPHCQKYGLAGSRGAFQRGRGGYIPDLVQSAFLPTVLAFLSGPHLLT", "length": 605, "header": "tr|A0A3Q2TXA2-1|A0A3Q2TXA2_CHICK Computationally mapped isoform of Zinc finger protein 341 OS=Gallus gallus OX=9031 GN=ZNF341 PE=4 SV=1 CANONICAL=A0A8V0ZTX0-1" }, "locus": { "chromosome": "20", "start_pos": 2505143, "end_pos": 2490062, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053571.1", "url": "https://www.ensembl.org/id/ENSGALT00010053571.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032281.1", "url": "https://www.ensembl.org/id/ENSGALP00010032281.1" } ] } }, { "isoform_ac": "A0A8V0ZLG0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTX0/entry#A0A8V0ZLG0-1", "sequence": { "sequence": "GGERLCLLPGMDNQTVLAVQSLLDGQGGVTDPSAQNVNAAAPMQPMDDEDVFLCGKCKKQFNSLPAFMTHKREQCQGNAPSLSTVSLATNSVYTPSITSVQQAPSTSRQQISTYITVPPSPLIQTLVQGNILVSDEVLMSAMSAFTSLDQPMPAVQPPVQSSLSMHAGAGYLSQPPPPPPPPPPPPPQPPPPPPPSLGAPGQPSTGSGVVEVYSAPAPMAANSSVEIQALGMQPYPAMEVPSQCVESPVYPSPPVYSPGKQGFKPKSASVPTPLTSAGGGNVVGFDSTSAVKSRRSKSESGLQEGKPKSPKLKCTYCDKAFTKNFDLQQHIRSHTGEKPFQCIVCGRAFAQKSNVKKHMQTHKVWPPGLGCTISRNSITVQVMALNPNQVEDEENTGLTQPSRNPAQPPQDMSPMDESDAGKLEAKQVVLIDSSYQCQFCPSKFNTYFQLKSHMTQHKNEQVYKCVVKSCAQTFQKLESFLDHIKSHQEELSYRCHLCSKDFPSLYELGVHQYSHSLLPQHSPKKDVAVYKCVKCVNKYSTPEALEHHLQTATHNFPCPHFLALMGQDPLVPFSLPSTSVRTGRLTRCFSERQGWLHP", "length": 598, "header": "tr|A0A8V0ZLG0-1|A0A8V0ZLG0_CHICK Computationally mapped isoform of Zinc finger protein 341 OS=Gallus gallus OX=9031 GN=ZNF341 PE=4 SV=1 CANONICAL=A0A8V0ZTX0-1" }, "locus": { "chromosome": "20", "start_pos": 2502348, "end_pos": 2490129, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053565.1", "url": "https://www.ensembl.org/id/ENSGALT00010053565.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032277.1", "url": "https://www.ensembl.org/id/ENSGALP00010032277.1" } ] } }, { "isoform_ac": "A0A8V0ZTX0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTX0/entry#A0A8V0ZTX0-1", "sequence": { "sequence": "MAQAIFEALEGMDNQTVLAVQSLLDGQGGVTDPSAQNVNAAAPMQPMDDEDVFLCGKCKKQFNSLPAFMTHKREQCQGNAPSLSTVSLATNSVYTPSITSVQQAPSTSRQQISTYITVPPSPLIQTLVQGNILVSDEVLMSAMSAFTSLDQPMPAVQPPVQSSLSMHAGAGYLSQPPPPPPPPPPPPPQPPPPPPPSLGAPGQPSTGSGVVEVYSAPAPMAANSSVEIQALGMQPYPAMEVPSQCVESPVYPSPPVYSPGKQGFKPKSASVPTPLTSAGGGNVVGFDSTSAVKSRRSKSESGLQEGKPKSPKLKCTYCDKAFTKNFDLQQHIRSHTGEKPFQCIVCGRAFAQKSNVKKHMQTHKVWPPGLGCTISRNSITVQVMALNPNQVEDEENTGLTQPSRNPAQPPQDMSPMDESDAGKLEAKQVVLIDSSYQCQFCPSKFNTYFQLKSHMTQHKNEQVYKCVVKSCAQTFQKLESFLDHIKSHQEELSYRCHLCSKDFPSLYELGVHQYSHSLLPQHSPKKDVAVYKCVKCVNKYSTPEALEHHLQTATHNFPCPHCQKVFPCERYLRRHIPTHGGGSKFKCQICKKFFRREHYLKLHAHIHSGEKPFKCSVCDAAFNRKDKLKRHMLIHEPFKKYKCPFSSHTGCNKEFNRPDKLKAHILSHSGMKIHKCQYCNKSFSRRAHMIEHQRSHTGNYKYRCPTCSKGFTRHKYMKDHKCRLGSPKDKDLQLRKPQKKRVVRGRKVGLSLPNQLALGELKDSVGGESPQEGVPNKEPFQESDAVLSIVVGGSGAADSDLVVPGQPSSIASNLSLAELQAASDGPCTMLAVPVYIQTTE", "length": 840, "header": "tr|A0A8V0ZTX0-1|A0A8V0ZTX0_CHICK Isoform 1 of Zinc finger protein 341 OS=Gallus gallus OX=9031 GN=ZNF341 PE=4 SV=1 CANONICAL=A0A8V0ZTX0-1" }, "locus": { "chromosome": "20", "start_pos": 2505143, "end_pos": 2486115, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053583.1", "url": "https://www.ensembl.org/id/ENSGALT00010053583.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032286.1", "url": "https://www.ensembl.org/id/ENSGALP00010032286.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:419152", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419152", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "E1BE18-1", "protein_name": "Zinc finger protein 341", "gene_name": "ZNF341", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAQTIFEALEGMDNQTVLAVQSLLDGQGAVPDPTGQSVSAPPAIQPLDDEDVFLCGKCKKQFNSLPAFMTHKREQCQGSALPLATVSLATNSIYTPSAAPSAIQQAPPPPNRQISTYITVPPSPLIQTLVQGNILVSDDVLMSAMSAFTSLDQPMPQGPQPVQSNLNMHPAPNYLAQPPPPPPPPPPLPPPPPPQPPPPPPQSLGPAGRPNPGGNGVVEVYNATAPLTGSGTVEIQALGMQPYPPLEVPNQCVEAPVYPTPQVYSPGKQGFKPKGPNPAAPMTSATGGTVASFDSPPSLKTRRTKGPSGLPEAAGKPKAQKLKCSYCDKSFTKNFDLQQHIRSHTGEKPFQCIACGRAFAQKSNVKKHMQTHKVWPPGRSGGTVSRNSVTVQVMALNPSRQEDEDNTGLGQTLSSAPQPQALPTAGEGEGDKLEAKQVVLIDSSYLCQFCPSKFSTYFQLKSHMTQHKNEQVYKCVVKSCAQTFPKLDTFLEHIKSHQEELSYRCHLCGKDFPSLYDLGVHQYSHSLLSQNSPKKDSAVYKCVKCVNKYSTPEALDHHLQTATHNFPCPHCQKVFPCERYLRRHLPTHGSGGRFKCQVCKKFFRREHYLKLHAHIHSGEKPYKCSVCESAFNRKDKLKRHMLIHEPFKKYKCPFSTHTGCSKEFNRPDKLKAHILSHSGMKLHKCALCSKSFSRRAHLAEHQRAHTGNYKFRCAGCAKGFSRHKYLKDHRCRLGPQKDKDLQARRPPRRRAAPRSGSGGGHKVVTPLPDPLGLEELKDTGAGPMPEAAPGKPPFSEPDAVLSIVVGGTVGGEPELVVPGHAEGLGSNLALAELQAGAEGSCAMLAVPVYIQASE", "length": 854 }, "evidence": [ { "id": "A0A8V0ZTX0", "url": "https://omabrowser.org/oma/group/A0A8V0ZTX0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F7ETL6-1", "protein_name": "Zinc finger protein 341", "gene_name": "Zfp341", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAQAIFEALEGMDNQTVLAVQSLLDGQGAVPDPTGQGVSAPPAIQPLDDEDVFLCGKCKKQFNSLPAFMTHKREQCQGNAPALATVSLATNSIYTPSAAPAAVQQAPPPANRQISTYITVPPSPLIQTLVQGNILVSDDVLMSAMSAFTSLDQPMPQGPSPVQNSLNMHPVPNYLTQPPPPPPPPPPLPPPPQPPPPPPQTLGPSGRSNPVGNSVVEVYSAAAPMAGNGTVDIQALGMQPYPPLEVPNQCVEAPVYPTPPVYSPGKQEFKPKGPNSTAPMTSATGSTVATFDPPPTLKTRRAKGASGLPEAAGKPKAQKLKCSYCDKSFTKNFDLQQHVRSHTGEKPFQCIACGRAFAQKSNVKKHMQTHKVWPPGRSGGTVSRNSVTVQVMALNPNRQEEEDTGLGQSLSSTTQPQALPTAGEEEGNKPEAKQVVLIDSSYLCQFCPSKFSTYFQLKSHMIQHKKEQVYKCVVKSCAQMFPKLDTFLEHIRSHQEELSYRCHLCSKDFPSLYDLGVHQYSHSLLPQHSPRKDSTVYKCVKCVNKYSTPEALEHHVQTATHSFPCPHCQKVFPCERYLRRHLPTHGSGGRFRCQICKKFFRKEHYLKLHAHIHSGEKPYKCSVCESAFNRKDKLKRHMLIHEPFKKYKCPFSMHTGCSKEFNRQDKLKAHILSHAGLKLHKCGLCSKSFSRRAHLAEHQHAHTGNYKFRCAGCAKGFSRHKYLKDHRCRLGPSKDKDLQTRRPPRRRATARGAGNIASVHKEENPLPDPLGLEELKAAGPSPEAAPGKPPFEQDAVLSIVVGGDPELVVPGHTEGLGSNLALAELQAGTEGGCAMLAVPVYIQASE", "length": 846 }, "evidence": [ { "id": "A0A8V0ZTX0", "url": "https://omabrowser.org/oma/group/A0A8V0ZTX0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9BYN7-1", "protein_name": "Zinc finger protein 341", "gene_name": "ZNF341", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAQAIFEALEGMDNQTVLAVQSLLDGQGAVPDPTGQSVNAPPAIQPLDDEDVFLCGKCKKQFNSLPAFMTHKREQCQGNAPALATVSLATNSIYPPSAAPTAVQQAPTPANRQISTYITVPPSPLIQTLVQGNILVSDDVLMSAMSAFTSLDQPMPQGPPPVQSSLNMHSVPSYLTQPPPPPPPPPPLPPPPPPQPPPPPPQSLGPPGRPNPGGNGVVEVYSAAAPLAGSGTVEIQALGMQPYPPLEVPNQCVEPPVYPTPTVYSPGKQGFKPKGPNPAAPMTSATGGTVATFDSPATLKTRRAKGARGLPEAAGKPKAQKLKCSYCDKSFTKNFDLQQHIRSHTGEKPFQCIACGRAFAQKSNVKKHMQTHKVWPPGHSGGTVSRNSVTVQVMALNPSRQEDEESTGLGQPLPGAPQPQALSTAGEEEGDKPESKQVVLIDSSYLCQFCPSKFSTYFQLKSHMTQHKNEQVYKCVVKSCAQTFPKLDTFLEHIKSHQEELSYRCHLCGKDFPSLYDLGVHQYSHSLLPQHSPKKDNAVYKCVKCVNKYSTPEALEHHLQTATHNFPCPHCQKVFPCERYLRRHLPTHGSGGRFKCQVCKKFFRREHYLKLHAHIHSGEKPYKCSVCESAFNRKDKLKRHMLIHEPFKKYKCPFSTHTGCSKEFNRPDKLKAHILSHSGMKLHKCALCSKSFSRRAHLAEHQRAHTGNYKFRCAGCAKGFSRHKYLKDHRCRLGPQKDKDLQTRRPPQRRAAPRSCGSGGRKVLTPLPDPLGLEELKDTGAGLVPEAVPGKPPFAEPDAVLSIVVGGAVGAETELVVPGHAEGLGSNLALAELQAGAEGPCAMLAVPVYIQASE", "length": 854 }, "evidence": [ { "id": "A0A8V0ZTX0", "url": "https://omabrowser.org/oma/group/A0A8V0ZTX0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTX0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTX0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTX0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTX0" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTX0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTX0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTX0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTX0" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTX0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTX0" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTX0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTX0" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity", "id": "GO:0001216", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001216", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTX0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTX0" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTX0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTX0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 14, "end_pos": 16, "annotation": "n_glycosylation_sequon" }, { "start_pos": 223, "end_pos": 225, "annotation": "n_glycosylation_sequon" }, { "start_pos": 680, "end_pos": 682, "annotation": "n_glycosylation_sequon" }, { "start_pos": 813, "end_pos": 815, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZTX0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTX0" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 53, "end_pos": 81, "start_aa": "Phe", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 14, "end_pos": 16 }, { "start_pos": 223, "end_pos": 225 }, { "start_pos": 680, "end_pos": 682 }, { "start_pos": 813, "end_pos": 815 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZTX8-1", "uniprot_ac": "A0A8V0ZTX8", "uniprot_id": "A0A8V0ZTX8_CHICK", "mass": { "chemical_mass": 169462.0, "monoisotopic_mass": 169462.0 }, "refseq": { "ac": "XP_040504344", "name": "ovostatin", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040504344" }, "gene_names": [ { "name": "OVSTL", "type": "recommended", "evidence": [ { "id": "A0A8V0ZTX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTX8" } ] }, { "name": "OVSTL", "type": "synonym", "evidence": [ { "id": "XP_040504344", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040504344" } ] } ], "protein_names": [ { "name": "Ovostatin", "type": "recommended", "evidence": [ { "id": "A0A8V0ZTX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTX8/entry#names_and_taxonomy" } ] }, { "name": "ovostatin", "type": "synonym", "evidence": [ { "id": "XP_040504344", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040504344" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040504344", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040504344" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTX8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTX8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "OVSTL", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTX8", "locus": {} } ], "crossref": [ { "id": "cd02897", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02897", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "425757", "url": "https://www.ncbi.nlm.nih.gov/gene/425757", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002890", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002890", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008930", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008930", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009048", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009048", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011625", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011625", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011626", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011626", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ 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"database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050473", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050473", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ECADFIW", "url": "https://omabrowser.org/oma/group/ECADFIW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZTX8", "url": "https://www.orthodb.org/?gene=A0A8V0ZTX8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11412", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11412", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11412:SF173", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11412:SF173", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00207", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00207", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01835", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01835", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07677", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07677", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07678", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07678", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07703", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07703", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17789", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17789", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17791", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17791", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040504344", "url": 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} ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTX8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTX8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1020, "end_pos": 1022, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1331, "end_pos": 1333, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1369, "end_pos": 1371, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1393, "end_pos": 1395, "annotation": "n_glycosylation_sequon" }, { "start_pos": 139, "end_pos": 141, "annotation": "n_glycosylation_sequon" }, { "start_pos": 356, "end_pos": 358, "annotation": "n_glycosylation_sequon" }, { "start_pos": 422, "end_pos": 424, "annotation": "n_glycosylation_sequon" }, { "start_pos": 428, "end_pos": 430, "annotation": "n_glycosylation_sequon" }, { 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"A0A8V0ZTX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTX9/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTX9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTX9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTX9", "locus": {} } ], "crossref": [ { "id": "A0A8V0ZTX9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZTX9", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00190", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00190", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001254", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001254", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001314", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001314", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009003", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009003", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018114", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018114", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050127", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050127", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR24264", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24264", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24264:SF15", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24264:SF15", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00089", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00089", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZTX9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTX9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZTX9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTX9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "GGYSCARSAVPYQVSLNSGYHFCGGSLISSQWVLSAAHCYKSSIQVKLGEYNLAAQDGSEQTISSSKVIRHSGYNANTLNNDIMLIKLSKAATLNSYVNTVPLPTSCVTAGTTCLISGWGNTLSSGCEYRIVSRNYLCMKKSPSRISVGSGNHGLLPMLITFAEHSLSVQGDSGGPVVCNGQLQGIVSWGFGCAQKGYPGVYTKVCNYVSWIKTTMSSN", "length": 219, "header": "tr|A0A8V0ZTX9-1|A0A8V0ZTX9_CHICK Isoform 1 of Peptidase S1 domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0ZTX9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZTX9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTX9/entry#A0A8V0ZTX9-1", "sequence": { "sequence": "GGYSCARSAVPYQVSLNSGYHFCGGSLISSQWVLSAAHCYKSSIQVKLGEYNLAAQDGSEQTISSSKVIRHSGYNANTLNNDIMLIKLSKAATLNSYVNTVPLPTSCVTAGTTCLISGWGNTLSSGCEYRIVSRNYLCMKKSPSRISVGSGNHGLLPMLITFAEHSLSVQGDSGGPVVCNGQLQGIVSWGFGCAQKGYPGVYTKVCNYVSWIKTTMSSN", "length": 219, "header": "tr|A0A8V0ZTX9-1|A0A8V0ZTX9_CHICK Isoform 1 of Peptidase S1 domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0ZTX9-1" }, "locus": { "chromosome": "1", "start_pos": 78140288, "end_pos": 78137881, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010057691.1", "url": "https://www.ensembl.org/id/ENSGALT00010057691.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035030.1", "url": "https://www.ensembl.org/id/ENSGALP00010035030.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "serine-type endopeptidase activity", "id": "GO:0004252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004252", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTX9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTX9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTX9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTX9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTX9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTX9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZTX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTX9" }, { "id": "PS50240", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50240" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Peptidase S1", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 217, "start_aa": "Gly", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZTZ3-1", "uniprot_ac": "A0A8V0ZTZ3", "uniprot_id": "A0A8V0ZTZ3_CHICK", "mass": { "chemical_mass": 73059.0, "monoisotopic_mass": 73059.0 }, "refseq": {}, "gene_names": [ { "name": "RNF214", "type": "recommended", "evidence": [ { "id": "A0A8V0ZTZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTZ3" } ] } ], "protein_names": [ { "name": "Ring finger protein 214", "type": "synonym", "evidence": [ { "id": "A0A8V0ZTZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTZ3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTZ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTZ3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RNF214", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTZ3", "locus": { "chromosome": "24", "start_pos": 5290502, "end_pos": 5280285, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010023123", "url": "https://www.ensembl.org/id/ENSGALG00010023123" } ] } } ], "crossref": [ { "id": "A0A8V0ZTZ3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZTZ3", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd16477", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16477", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "419767", "url": "https://www.ncbi.nlm.nih.gov/gene/419767", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056872", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056872", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:419767", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419767", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZLI1", "url": "https://www.orthodb.org/?gene=A0A8V0ZLI1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZTY0", "url": "https://www.orthodb.org/?gene=A0A8V0ZTY0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZTZ3", "url": "https://www.orthodb.org/?gene=A0A8V0ZTZ3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZZE9", "url": "https://www.orthodb.org/?gene=A0A8V0ZZE9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZZG9", "url": "https://www.orthodb.org/?gene=A0A8V0ZZG9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15727", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15727", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15727:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15727:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF24525", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24525", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-983168", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983168", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZLI1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLI1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLI1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLI1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZTY0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTY0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZTY0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTY0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZTZ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTZ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZTZ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTZ3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZZE9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZE9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZZE9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZE9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZZG9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZG9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZZG9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZG9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "PPWESSRGKPHSLRSAAAVRTAASPPRLTAGRHAAHRALPGRSRLKSSSACPGSGRPARLRASPRSGAGQPRGRSPSPSPRTPCRAPTSNASPRSRPRSPCMGRRRPPVPLRCRMPAASDSGVTSARCFGMPPALEVTGGRSGCLWGGSNGSRHPLQTDFKTADTDVNTDQDIEKNLDKMMSERALLKERYQEVLDKQRQVENQLQVQLKQLQQRREEEMKNHQEILKAIQAVTIKREETKKKMEKEKKEFLQKEQDLKAEIEKLCEKGRRQLWEMELDKLKNQHNEINRNILEETERAWKAEILSLESRKELLVLKLEEAEKEAELHLTYLKSAPPTLETMRPKQEWEMRLNRIRMTKESVRDQFNDHIQMVRNGTKLSSLPQIPTPTLPPPPSETDFMLTAFQPNPSLTPRLPFPIGPVPVPMVMPSADPRALSFPLLNPAISRPNQPSPPLPASQGRNSPVVASLIGTHSPHMTPAASIPPPPGLGGVKVTPEFHRPQPADKLEKLLEKLLTRFPQCNKAQLTNILQQIKTARRTMAGLTMEELNQLVAAKLAEQQERAAAGAQPLSRIRAPMFSAPLPQISTPMFLPPAQVAYPGTASHTPAACKLCLMCQKLVQPSDLHPMACSHVLHKECIKFWAQTNTNDTCPFCPSLK", "length": 656, "header": "tr|A0A8V0ZTZ3-1|A0A8V0ZTZ3_CHICK Isoform 1 of Ring finger protein 214 OS=Gallus gallus OX=9031 GN=RNF214 PE=1 SV=1 CANONICAL=A0A8V0ZTZ3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZLI1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTZ3/entry#A0A8V0ZLI1-1", "sequence": { "sequence": "MPLLGVFGIIKVQAAFGALQKLLFRMPPHAVMLCKQSVHRSPYCFGFGCRVAVGPVGEEVMALELPDAAHVHQPRGPGQLLRPLLHLLLRHIQADGPRQLPGTVGHSTAIIELRAAGQSVGQHGGDPGSAQPKARVDAAHGLRSCAPSPQPPLPMRHQTGRLGKSRKRRTVTKKGNGDKKRGTTDFKTADTDVNTDQDIEKNLDKMMSERALLKERYQEVLDKQRQVENQLQVQLKQLQQRREEEMKNHQEILKAIQAVTIKREETKKKMEKEKKEFLQKEQDLKAEIEKLCEKGRRLLKEQEEKENKIASLIAEQSDEKQLWEMELDKLKNQHNEINRNILEETERAWKAEILSLESRKELLVLKLEEAEKEAELHLTYLKSAPPTLETMRPKQEWEMRLNRIRMTKESVRDQFNDHIQMVRNGTKLSSLPQIPTPTLPPPPSETDFMLTAFQPNPSLTPRLPFPIGPVPVPMVMPSADPRALSFPLLNPAISRPNQPSPPLPASQGRNSPVVASLIGTHSPHMTPAASIPPPPGLGGVKVTPEFHRPQPADKLEKLLEKLLTRFPQCNK", "length": 571, "header": "tr|A0A8V0ZLI1-1|A0A8V0ZLI1_CHICK Computationally mapped isoform of Ring finger protein 214 OS=Gallus gallus OX=9031 GN=RNF214 PE=1 SV=1 CANONICAL=A0A8V0ZTZ3-1" }, "locus": { "chromosome": "24", "start_pos": 5288246, "end_pos": 5280484, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056486.1", "url": "https://www.ensembl.org/id/ENSGALT00010056486.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034229.1", "url": "https://www.ensembl.org/id/ENSGALP00010034229.1" } ] } }, { "isoform_ac": "A0A8V0ZTY0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTZ3/entry#A0A8V0ZTY0-1", "sequence": { "sequence": "QRRHVRARPSAARPPLRQGAPSPRALPAAAGRGGAGRAVRGPSGAAPGPAAASGGTAMAAGPGRRGRAAARWRAAGDLFAAGQSEGAAEEHDPEAAPVKPSQNIAVQTDFKTADTDVNTDQDIEKNLDKMMSERALLKERYQEVLDKQRQVENQLQVQLKQLQQRREEEMKNHQEILKAIQAVTIKREETKKKMEKEKKEFLQKEQDLKAEIEKLCEKGRRQLWEMELDKLKNQHNEINRNILEETERAWKAEILSLESRKELLVLKLEEAEKEAELHLTYLKSAPPTLETMRPKQEWEMRLNRIRMTKESVRDQFNDHIQMVRNGTKLSSLPQIPTPTLPPPPSETDFMLTAFQPNPSLTPRLPFPIGPVPVPMVMPSADPRALSFPLLNPAISRPNQPSPPLPASQGRNSPVVASLIGTHSPHMTPAASIPPPPGLGGVKVTPEFHRPQPADKLEKLLEKLLTRFPQCNKAQLTNILQQIKTARRTMAGLTMEELNQLVAAKLAEQQERAAAGAQPLSRIRAPMFSAPLPQISTPMFLPPAQVAYPGTASHTPAACKLCLMCQKLVQPSDLHPMACSHVLHKECIKFWAQTNTNDTCPFCPSLK", "length": 606, "header": "tr|A0A8V0ZTY0-1|A0A8V0ZTZ3_CHICK Computationally mapped isoform of Ring finger protein 214 OS=Gallus gallus OX=9031 GN=RNF214 PE=1 SV=1 CANONICAL=A0A8V0ZTZ3-1" }, "locus": { "chromosome": "24", "start_pos": 5290310, "end_pos": 5281540, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056549.1", "url": "https://www.ensembl.org/id/ENSGALT00010056549.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034291.1", "url": "https://www.ensembl.org/id/ENSGALP00010034291.1" } ] } }, { "isoform_ac": "A0A8V0ZTZ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTZ3/entry#A0A8V0ZTZ3-1", "sequence": { "sequence": "PPWESSRGKPHSLRSAAAVRTAASPPRLTAGRHAAHRALPGRSRLKSSSACPGSGRPARLRASPRSGAGQPRGRSPSPSPRTPCRAPTSNASPRSRPRSPCMGRRRPPVPLRCRMPAASDSGVTSARCFGMPPALEVTGGRSGCLWGGSNGSRHPLQTDFKTADTDVNTDQDIEKNLDKMMSERALLKERYQEVLDKQRQVENQLQVQLKQLQQRREEEMKNHQEILKAIQAVTIKREETKKKMEKEKKEFLQKEQDLKAEIEKLCEKGRRQLWEMELDKLKNQHNEINRNILEETERAWKAEILSLESRKELLVLKLEEAEKEAELHLTYLKSAPPTLETMRPKQEWEMRLNRIRMTKESVRDQFNDHIQMVRNGTKLSSLPQIPTPTLPPPPSETDFMLTAFQPNPSLTPRLPFPIGPVPVPMVMPSADPRALSFPLLNPAISRPNQPSPPLPASQGRNSPVVASLIGTHSPHMTPAASIPPPPGLGGVKVTPEFHRPQPADKLEKLLEKLLTRFPQCNKAQLTNILQQIKTARRTMAGLTMEELNQLVAAKLAEQQERAAAGAQPLSRIRAPMFSAPLPQISTPMFLPPAQVAYPGTASHTPAACKLCLMCQKLVQPSDLHPMACSHVLHKECIKFWAQTNTNDTCPFCPSLK", "length": 656, "header": "tr|A0A8V0ZTZ3-1|A0A8V0ZTZ3_CHICK Isoform 1 of Ring finger protein 214 OS=Gallus gallus OX=9031 GN=RNF214 PE=1 SV=1 CANONICAL=A0A8V0ZTZ3-1" }, "locus": { "chromosome": "24", "start_pos": 5290310, "end_pos": 5281181, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056564.1", "url": "https://www.ensembl.org/id/ENSGALT00010056564.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034306.1", "url": "https://www.ensembl.org/id/ENSGALP00010034306.1" } ] } }, { "isoform_ac": "A0A8V0ZZE9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTZ3/entry#A0A8V0ZZE9-1", "sequence": { "sequence": "MALEQAQAEGPAAAPPASLSAPESPGEAAPGGEAEPAALPGEAPAAEGEGEPGPGGGAEAAGQSEGAAEEHDPEAAPVKPSQNIAVQTDFKTADTDVNTDQDIEKNLDKMMSERALLKERYQEVLDKQRQVENQLQVQLKQLQQRREEEMKNHQEILKAIQAVTIKREETKKKMEKEKKEFLQKEQDLKAEIEKLCEKGRRLLKEQEEKENKIASLIAEQSDEKQLWEMELDKLKNQHNEINRNILEETERAWKAEILSLESRKELLVLKLEEAEKEAELHLTYLKSAPPTLETMRPKQEWEMRLNRIRMTKESVRDQFNDHIQMVRNGTKLSSLPQIPTPTLPPPPSETDFMLTAFQPNPSLTPRLPFPIGPVPVPMVMPSADPRALSFPLLNPAISRPNQPSPPLPASQGRNSPVVASLIGTHSPHMTPAASIPPPPGLGGVKVTPEFHRPQPADKLEKLLEKLLTRFPQCNKAQLTNILQQIKTARRTMAGLTMEELNQLVAAKLAEQQERAAAGAQPLSRIRAPMFSAPLPQISTPMFLPPAQVAYPGTASHTPAACKLCLMCQKLVQPSDLHPMACSHVLHKECIKFWAQTNTNDTCPFCPSLK", "length": 609, "header": "tr|A0A8V0ZZE9-1|A0A8V0ZTZ3_CHICK Computationally mapped isoform of Ring finger protein 214 OS=Gallus gallus OX=9031 GN=RNF214 PE=1 SV=1 CANONICAL=A0A8V0ZTZ3-1" }, "locus": { "chromosome": "24", "start_pos": 5290310, "end_pos": 5281711, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056540.1", "url": "https://www.ensembl.org/id/ENSGALT00010056540.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034282.1", "url": "https://www.ensembl.org/id/ENSGALP00010034282.1" } ] } }, { "isoform_ac": "A0A8V0ZZG9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTZ3/entry#A0A8V0ZZG9-1", "sequence": { "sequence": "AAAVRTAASPPRLTAGRHAAHRALPGRSRLKSSSACPGSGRPARLRASPRSGAGQPRGRSPSPSPRTPCRAPTSNASPRSRPRSPCMGRRRPPVPLRCRMPAASDSGVTSARCFGMPPALEVTGGRSGCLWGGSNGSRHPLQTDFKTADTDVNTDQDIEKNLDKMMSERALLKERYQEVLDKQRQVENQLQVQLKQLQQRREEEMKNHQEILKAIQAVTIKREETKKKMEKEKKEFLQKEQDLKAEIEKLCEKGRRQLWEMELDKLKNQHNEINRNILEETERAWKAEILSLESRKELLVLKLEEAEKEAELHLTYLKSAPPTLETMRPKQEWEMRLNRIRMTKESVRDQFNDHIQMVRNGTKLSSLPQIPTPTLPPPPSETDFMLTAFQPNPSLTPRLPFPIGPVPVPMVMPSADPRALSFPLLNPAISRPNQPSPPLPASQGRNSPVVASLIGTHSPHMTPAASIPPPPGLGGVKVTPEFHRPQPADKLEKLLEKLLTRFPQCNKAQLTNILQQIKTARRTMAGLTMEELNQLVAAKLAEQQERAAAGAQTPAACKLCLMCQKLVQPSDLHPMACSHVLHKECIKFWAQTNTNDTCPFCPSLK", "length": 605, "header": "tr|A0A8V0ZZG9-1|A0A8V0ZTZ3_CHICK Computationally mapped isoform of Ring finger protein 214 OS=Gallus gallus OX=9031 GN=RNF214 PE=1 SV=1 CANONICAL=A0A8V0ZTZ3-1" }, "locus": { "chromosome": "24", "start_pos": 5290310, "end_pos": 5281226, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056561.1", "url": "https://www.ensembl.org/id/ENSGALT00010056561.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034303.1", "url": "https://www.ensembl.org/id/ENSGALP00010034303.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:419767", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419767", "resource": "KEGG Pathway" }, { "id": "R-GGA-983168", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983168", "resource": "Reactome", "description": "Antigen processing: Ubiquitination & Proteasome degradation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTZ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTZ3" } ], "pmid": "" }, { "name": "ubiquitin-protein transferase activity", "id": "GO:0004842", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004842", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTZ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTZ3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 150, "end_pos": 152, "annotation": "n_glycosylation_sequon" }, { "start_pos": 375, "end_pos": 377, "annotation": "n_glycosylation_sequon" }, { "start_pos": 646, "end_pos": 648, "annotation": "n_glycosylation_sequon" }, { "start_pos": 90, "end_pos": 92, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZTZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTZ3" }, { "id": "PS50089", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50089" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RING-type", "eco_id": "ECO_0000259", "start_pos": 611, "end_pos": 652, "start_aa": "Cys", "end_aa": "Cys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 150, "end_pos": 152 }, { "start_pos": 375, "end_pos": 377 }, { "start_pos": 646, "end_pos": 648 }, { "start_pos": 90, "end_pos": 92 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZU10-1", "uniprot_ac": "A0A8V0ZU10", "uniprot_id": "A0A8V0ZU10_CHICK", "mass": { "chemical_mass": 103971.0, "monoisotopic_mass": 103971.0 }, "refseq": {}, "gene_names": [ { "name": "SMTN", "type": "recommended", "evidence": [ { "id": "A0A8V0ZU10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU10" } ] } ], "protein_names": [ { "name": "Smoothelin", "type": "synonym", "evidence": [ { "id": "A0A8V0ZU10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU10/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZU10", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU10" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SMTN", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU10", "locus": { "chromosome": "15", "start_pos": 9996305, "end_pos": 9976862, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022072", "url": "https://www.ensembl.org/id/ENSGALG00010022072" } ] } } ], "crossref": [ { "id": "A0A8V0ZU10", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZU10", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd21258", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21258", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd21259", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21259", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001715", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001715", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022189", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022189", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036872", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036872", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050540", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050540", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZLK6", "url": "https://www.orthodb.org/?gene=A0A8V0ZLK6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZNC9", "url": "https://www.orthodb.org/?gene=A0A8V0ZNC9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZNE3", "url": "https://www.orthodb.org/?gene=A0A8V0ZNE3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZU10", "url": "https://www.orthodb.org/?gene=A0A8V0ZU10", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23167", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23167", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23167:SF52", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23167:SF52", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00307", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00307", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12510", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12510", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZLK6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLK6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLK6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLK6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZNC9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNC9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZNC9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNC9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZNE3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNE3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZNE3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNE3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZU10", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU10", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZU10-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU10-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSQESLQGMDEGALRKLLEATLDLAERRRIRSAIRELQRQELERDEEALASKRFRTERGSHRQDNKENWLRSQQLEEEQQKALASLSRELESITDVEELTKLLRAASEYEERKLIRAAIRKLRAEEIEAATLAGNVQSSRRDGAEPAAVPARAERSRRDDAETAALVGNGESSQRAGSELLAVVSVESSAEPVENSRRGDAEQAVLSRTEESSHGGDADRLPAEEPERSVAHEQEEEQEHRQAELQDLSNQQLREPQKPPAQASGTLVLLDLHPALEPTAAPQPDERTAEVELRTERASECELQYREEGSGSSCSAREPVVEPAEALCSTGQSRQAEQHGPTQPCAGTQSGQFVICVRGQVSGKAVMPQEKPAAPTQSAARTPSRLNAQRWEQTPSSPCPQGRAEPSPVQRSSSVRERAQRFTPSGATPVGTAGRQRAAAGGPEGAGGAAGRAGPGQWQRGPRTAPPGPAQNARGAGGGGAEQRPPPAGPRPAGTGPTAAHDGMKTYFTIEIKDGRVQPHTQSVTPRIVAAPGSQRAELTLGLRSTPIRITAIPSSTGGICSISTSSNVVKPMEPELVVEQPQAPRLQPELPNGMEKVQVREVEKKSKLNVEELNRIEDEDVLDKMLDQTTDFEERRLIRNAMRELRQRKRDQREKERDQRLQEMKSQATVSRAGHNTETTTTQSTQSADGSARSTVTKTERLIQSNDGSKTSRTTTMESSYVKRSDNGSSSTFVQTKSSYSSSSKKTGSIFDREDESASRQSSLAALERRQAEKKKELMKAQSLPKTSTSQARKAMIEKLQKEGGSSPNPAAPRAAVQRSSSCGVPNANSIKQMLLDWCRAKTRGYEHVDIQNFSSSWSDGMAFCALVHNFFPDAFDYSQLTPQNRRHNFEVAFSSAEKHADCPQLLDVEDMVRMREPDWKCVYTYIQEFYRCLVQKGLVKTKKS", "length": 946, "header": "tr|A0A8V0ZU10-1|A0A8V0ZU10_CHICK Isoform 1 of Smoothelin OS=Gallus gallus OX=9031 GN=SMTN PE=1 SV=1 CANONICAL=A0A8V0ZU10-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZLK6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU10/entry#A0A8V0ZLK6-1", "sequence": { "sequence": "MVGWMVGAGRTGGRGSSGGMWDAGGRAWALQKGRSVAALALWLQGSSLSGCPLPSHSPSSSPTALSLPGPAAQPQSTAQPRARAPSPQTRLCAGVGVVQSAIPAAALCAMQPCLPVSGQDASVRSPGLSLTPGGLGSPWRAAGSVHLRGEGTLGGPGSPLTQQLPLALAVPAALSVHQSSELCCRSRMRRSRFLSPSAGTGLSLSGWSAPRVPAASFAELTLGLRSTPIRITAIPSSTGGICSISTSSNVVKDPCAHFEGTEESGSPVAHPPTFSSTRQLHLSRSNSFPMEPELVVEQPQAPRLQPELPNGMEKKSKLNVEELNRIEDEDVLDKMLDQTTDFEERRLIRNAMRELRQRKRDQREKERDQRLQEMKSQATVSRAGHNTETTTTQSTQSADGSARSTVTKTERLIQSNDGSKTSRTTTMESSYVKRSDNGSSSTFVQTKSSYSSSSKKTGSIFDREDESASRQSSLAALERRQAEKKKELMKAQSLPKTSTSQARKAMIEKLQKEGGSSPNPAAPRAAVQRSSSCGVPNANSIKQMLLDWCRAKTRGYEHVDIQNFSSSWSDGMAFCALVHNFFPDAFDYSQLTPQNRRHNFEVAFSSAEMLADCVPLVEVEDMMIMGKKPDAKCVFTYVQSLYNHLRRHEMRMRQKEC", "length": 657, "header": "tr|A0A8V0ZLK6-1|A0A8V0ZLK6_CHICK Computationally mapped isoform of Smoothelin OS=Gallus gallus OX=9031 GN=SMTN PE=1 SV=1 CANONICAL=A0A8V0ZU10-1" }, "locus": { "chromosome": "15", "start_pos": 9995430, "end_pos": 9985157, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053672.1", "url": "https://www.ensembl.org/id/ENSGALT00010053672.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032328.1", "url": "https://www.ensembl.org/id/ENSGALP00010032328.1" } ] } }, { "isoform_ac": "A0A8V0ZNC9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU10/entry#A0A8V0ZNC9-1", "sequence": { "sequence": "MKTYFTIEIKDGRVQPHTQSVTPRIVAAPGSQRAELTLGLRSTPIRITAIPSSTGGICSISTSSNVVKPMEPELVVEQPQAPRLQPELPNGMEKVQVREVEKKSKLNVEELNRIEDEDVLDKMLDQTTDFEERRLIRNAMRELRQRKRDQREKERDQRLQEMKSQATVSRAGHNTETTTTQSTQSADGSARSTVTKTERLIQSNDGSKTSRTTTMESSYVKRSDSKSFACVSCSIFDREDESASRQSSLAALERRQAEKKKELMKAQSLPKTSTSQARKAMIEKLQKEGGSSPNPAAPRAAVQRSSSCGVPNANSIKQMLLDWCRAKTRGYEHVDIQNFSSSWSDGMAFCALVHNFFPDAFDYSQLTPQNRRHNFEVAFSSAEKHADCPQLLDVEDMVRMREPDWKCVYTYIQEFYRCLVQKGLVKTKKS", "length": 430, "header": "tr|A0A8V0ZNC9-1|A0A8V0ZNC9_CHICK Computationally mapped isoform of Smoothelin OS=Gallus gallus OX=9031 GN=SMTN PE=1 SV=1 CANONICAL=A0A8V0ZU10-1" }, "locus": { "chromosome": "15", "start_pos": 9992807, "end_pos": 9984970, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053666.1", "url": "https://www.ensembl.org/id/ENSGALT00010053666.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032325.1", "url": "https://www.ensembl.org/id/ENSGALP00010032325.1" } ] } }, { "isoform_ac": "A0A8V0ZNE3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU10/entry#A0A8V0ZNE3-1", "sequence": { "sequence": "MSQESLQGMDEGALRKLLEATLDLAERRRIRSAIRELQRQELERDEEALASKRFRTERGSHRQDNKENWLRSQQLEEEQQKALASLSRELESITDVEELTKLLRAASEYEERKLIRAAIRKLRAEEIEAATLAGNVQSSRRDGAEPAAVPARAERSRRDDAETAALVGNGESSQRAGSELLAVVSVESSAEPVENSRRGDAEQAVLSRTEESSHGGDADRLPAEEPERSVAHEQEEEQEHRQAELQDLSNQQLREPQKPPAQASGTLVLLDLHPALEPTAAPQPDERTAEVELRTERASECELQYREEGSGSSCSAREPVVEPAEALCSTGQSRQAEQHGPTQPCAGTQSGQFVICVRGQVSGKAVMPQEKPAAPTQSAARTPSRLNAQRWEQTPSSPCPQGRAELTLGLRSTPIRITAIPSSTGGICSISTSSNVVKPMEPELVVEQPQAPRLQPELPNGMEKVQVREVEKKSKLNVEELNRIEDEDVLDKMLDQTTDFEERRLIRNAMRELRQRKRDQREKERDQRLQEMKSQATVSRAGHNTETTTTQSTQSADGSARSTVTKTERLIQSNDGSKTSRTTTMESSYVKRSDNGSSSTFVQTKSSYSSSSKKTGSIFDREDESASRQSSLAALERRQAEKKKELMKAQSLPKTSTSQARKAMIEKLQKEGGSSPNPAAPRAAVQRSSSCGVPNANSIKQMLLDWCRAKTRGYEHVDIQNFSSSWSDGMAFCALVHNFFPDAFDYSQLTPQNRRHNFEVAFSSAEMLADCVPLVEVEDMMIMGKKPDAKCVFTYVQSLYNHLRRHEMRMRQKEC", "length": 815, "header": "tr|A0A8V0ZNE3-1|A0A8V0ZNE3_CHICK Computationally mapped isoform of Smoothelin OS=Gallus gallus OX=9031 GN=SMTN PE=1 SV=1 CANONICAL=A0A8V0ZU10-1" }, "locus": { "chromosome": "15", "start_pos": 9995430, "end_pos": 9976976, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053688.1", "url": "https://www.ensembl.org/id/ENSGALT00010053688.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032341.1", "url": "https://www.ensembl.org/id/ENSGALP00010032341.1" } ] } }, { "isoform_ac": "A0A8V0ZU10-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU10/entry#A0A8V0ZU10-1", "sequence": { "sequence": "MSQESLQGMDEGALRKLLEATLDLAERRRIRSAIRELQRQELERDEEALASKRFRTERGSHRQDNKENWLRSQQLEEEQQKALASLSRELESITDVEELTKLLRAASEYEERKLIRAAIRKLRAEEIEAATLAGNVQSSRRDGAEPAAVPARAERSRRDDAETAALVGNGESSQRAGSELLAVVSVESSAEPVENSRRGDAEQAVLSRTEESSHGGDADRLPAEEPERSVAHEQEEEQEHRQAELQDLSNQQLREPQKPPAQASGTLVLLDLHPALEPTAAPQPDERTAEVELRTERASECELQYREEGSGSSCSAREPVVEPAEALCSTGQSRQAEQHGPTQPCAGTQSGQFVICVRGQVSGKAVMPQEKPAAPTQSAARTPSRLNAQRWEQTPSSPCPQGRAEPSPVQRSSSVRERAQRFTPSGATPVGTAGRQRAAAGGPEGAGGAAGRAGPGQWQRGPRTAPPGPAQNARGAGGGGAEQRPPPAGPRPAGTGPTAAHDGMKTYFTIEIKDGRVQPHTQSVTPRIVAAPGSQRAELTLGLRSTPIRITAIPSSTGGICSISTSSNVVKPMEPELVVEQPQAPRLQPELPNGMEKVQVREVEKKSKLNVEELNRIEDEDVLDKMLDQTTDFEERRLIRNAMRELRQRKRDQREKERDQRLQEMKSQATVSRAGHNTETTTTQSTQSADGSARSTVTKTERLIQSNDGSKTSRTTTMESSYVKRSDNGSSSTFVQTKSSYSSSSKKTGSIFDREDESASRQSSLAALERRQAEKKKELMKAQSLPKTSTSQARKAMIEKLQKEGGSSPNPAAPRAAVQRSSSCGVPNANSIKQMLLDWCRAKTRGYEHVDIQNFSSSWSDGMAFCALVHNFFPDAFDYSQLTPQNRRHNFEVAFSSAEKHADCPQLLDVEDMVRMREPDWKCVYTYIQEFYRCLVQKGLVKTKKS", "length": 946, "header": "tr|A0A8V0ZU10-1|A0A8V0ZU10_CHICK Isoform 1 of Smoothelin OS=Gallus gallus OX=9031 GN=SMTN PE=1 SV=1 CANONICAL=A0A8V0ZU10-1" }, "locus": { "chromosome": "15", "start_pos": 9992807, "end_pos": 9976976, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053679.1", "url": "https://www.ensembl.org/id/ENSGALT00010053679.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032332.1", "url": "https://www.ensembl.org/id/ENSGALP00010032332.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 428, "start_aa": "Thr", "end_pos": 428, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr428", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 498, "start_aa": "Thr", "end_pos": 498, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr498", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZU10", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU10" } ], "pmid": "" }, { "name": "actin cytoskeleton", "id": "GO:0015629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015629", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZU10", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU10" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "actin cytoskeleton organization", "id": "GO:0030036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030036", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZU10", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU10" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 728, "end_pos": 730, "annotation": "n_glycosylation_sequon" }, { "start_pos": 854, "end_pos": 856, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZU10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU10" }, { "id": "PS50021", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50021" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Calponin-homology (CH)", "eco_id": "ECO_0000259", "start_pos": 830, "end_pos": 936, "start_aa": "Asn", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 428, 498 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 728, "end_pos": 730 }, { "start_pos": 854, "end_pos": 856 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZU11-1", "uniprot_ac": "A0A8V0ZU11", "uniprot_id": "A0A8V0ZU11_CHICK", "mass": { "chemical_mass": 35344.0, "monoisotopic_mass": 35344.0 }, "refseq": {}, "gene_names": [ { "name": "SHISA4", "type": "recommended", "evidence": [ { "id": "A0A8V0ZU11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU11" } ] } ], "protein_names": [ { "name": "Shisa family member 4", "type": "synonym", "evidence": [ { "id": "A0A8V0ZU11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU11/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZU11", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU11" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SHISA4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU11", "locus": { "chromosome": "26", "start_pos": 1172210, "end_pos": 1176508, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010024683", "url": "https://www.ensembl.org/id/ENSGALG00010024683" } ] } } ], "crossref": [ { "id": "A0A8V0ZU11", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZU11", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR026910", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026910", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR053891", "url": "https://www.ebi.ac.uk/interpro/entry/IPR053891", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZU11", "url": "https://www.orthodb.org/?gene=A0A8V0ZU11", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31395", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31395", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31395:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31395:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13908", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13908", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF27717", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27717", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZU11", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU11", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZU11-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU11-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGPIPYRGWVWGEREQEWGWDGAQGWGTRVGRGREWTLGVGTGMEWGWDGDRDRCRRGRPRGKDSAGLREGCGERGRAGALRPVGAGWGRCVRREAVPRGGTGRRPSSTGCGVTAGLHRTGTAAGTARGTQRPPPPRPPDGPRRQPLAAGRHRADDRGRFAGNGSWHPGFDCEAFSFCCGSCHQRYCCYDPLRLLTERQQRHCLAFSPKTIAGIASAVVLFIAIVTTIVCCFMCSCCYLYQRRQHLRTPLQGPEIPLTSYPAPPPAPFPVDPKAGPVPPQPGFTPMAMYPPTGPAAQYPLYPSGPPVYNPTAPPPYVPAQPSYPGA", "length": 326, "header": "tr|A0A8V0ZU11-1|A0A8V0ZU11_CHICK Isoform 1 of Shisa family member 4 OS=Gallus gallus OX=9031 GN=SHISA4 PE=4 SV=1 CANONICAL=A0A8V0ZU11-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZU11-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU11/entry#A0A8V0ZU11-1", "sequence": { "sequence": "MGPIPYRGWVWGEREQEWGWDGAQGWGTRVGRGREWTLGVGTGMEWGWDGDRDRCRRGRPRGKDSAGLREGCGERGRAGALRPVGAGWGRCVRREAVPRGGTGRRPSSTGCGVTAGLHRTGTAAGTARGTQRPPPPRPPDGPRRQPLAAGRHRADDRGRFAGNGSWHPGFDCEAFSFCCGSCHQRYCCYDPLRLLTERQQRHCLAFSPKTIAGIASAVVLFIAIVTTIVCCFMCSCCYLYQRRQHLRTPLQGPEIPLTSYPAPPPAPFPVDPKAGPVPPQPGFTPMAMYPPTGPAAQYPLYPSGPPVYNPTAPPPYVPAQPSYPGA", "length": 326, "header": "tr|A0A8V0ZU11-1|A0A8V0ZU11_CHICK Isoform 1 of Shisa family member 4 OS=Gallus gallus OX=9031 GN=SHISA4 PE=4 SV=1 CANONICAL=A0A8V0ZU11-1" }, "locus": { "chromosome": "26", "start_pos": 1176309, "end_pos": 1173214, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010060260.1", "url": "https://www.ensembl.org/id/ENSGALT00010060260.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010037020.1", "url": "https://www.ensembl.org/id/ENSGALP00010037020.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZU11", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU11" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 163, "end_pos": 165, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZU11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU11" }, { "id": "PF13908", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13908" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Shisa N-terminal", "eco_id": "ECO_0000259", "start_pos": 162, "end_pos": 203, "start_aa": "Gly", "end_aa": "Cys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 163, "end_pos": 165 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZU17-1", "uniprot_ac": "A0A8V0ZU17", "uniprot_id": "A0A8V0ZU17_CHICK", "mass": { "chemical_mass": 116333.0, "monoisotopic_mass": 116333.0 }, "refseq": { "ac": "XP_015134701", "name": "L-fucose kinase isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015134701" }, "gene_names": [ { "name": "FUK", "type": "recommended", "evidence": [ { "id": "A0A8V0ZU17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU17" } ] }, { "name": "FUK", "type": "synonym", "evidence": [ { "id": "XP_015134701", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015134701" } ] } ], "protein_names": [ { "name": "L-fucose kinase", "type": "recommended", "evidence": [ { "id": "A0A8V0ZU17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU17/entry#names_and_taxonomy" } ] }, { "name": "2.7.1.52", "type": "synonym", "evidence": [ { "id": "A0A8V0ZU17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU17/entry#names_and_taxonomy" } ] }, { "name": "L-fucose kinase isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015134701", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015134701" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052542.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015134701.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015134701", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015134701" } ] }, { "annotation": "Takes part in the salvage pathway for reutilization of fucose from the degradation of oligosaccharides.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZU17", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU17#function" }, { "database": "UniProtKB", "id": "ARBA00059365", "url": "https://www.uniprot.org/uniprotkb/ARBA00059365#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZU17", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU17" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FUK", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU17", "locus": {} } ], "crossref": [ { "id": "A0A8V0ZU17", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZU17", "database": "AlphaFoldDB", "categories": [] }, { "id": "770049", "url": "https://www.ncbi.nlm.nih.gov/gene/770049", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006204", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006204", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012887", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012887", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013750", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013750", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020568", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020568", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036554", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036554", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052203", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052203", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:770049", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:770049", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QRWREAW", "url": "https://omabrowser.org/oma/group/QRWREAW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZU17", "url": "https://www.orthodb.org/?gene=A0A8V0ZU17", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR32463", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR32463", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR32463:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR32463:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00288", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00288", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07959", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07959", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08544", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08544", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-6787639", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6787639", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015134701", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015134701", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "13241", "url": "https://www.rhea-db.org/rhea/13241", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZU17", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU17", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZU17-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU17-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAGVEWTAIVLTCRRGGGVAALQRELELRRRRGALGRRPVLVLALEDPWAGVGSGGATLNAVLVAAEHLSARAGCTVVSADALKEARILILHTGREFSFDDCGRAFTCLPAEQPRAAAEALVCNLDSLLGTVTQRLCVGSPPGVWVCSTDMLLSVPSVPGIDWDGFQGVRVIAVPGSQAYARNHGVYLADEQGLVRDIIYKGTETQIQQCAGPDGTVPLVCGVVFFSSSAAEQLLATHVIPPLDACTYMGLDSGAPPIQLSLFFDIVLSMAGGMTEEDFVKGGGDASVRSARSVLWTALRAFPLSMACIPDASYDYLTTAASDHIRSLTLLPSSTSHLRFCKTAHSHVDQPLLLEDGSSVTNCLLEGAVRLAAGSVIQHCHLQGPLEIGPGCLLTGLTVDSSPALQGCPLRDVVLQGHHVRLRDLPCRVFTLTGRLDDWQSPAEEATYLNISWAEFFHRTGIRKGDLWDAETPQKDRCLLSARLFPVLHASEALGLEDVLWLLAPAVSGERLARWRAAWRMSWQELLPCLDKAAELGARRDLFFLQGQHKVQCVLLGRQDGSLLPLIRSAVHEGYHEALLGTLDEVASTADDAGIAARALACIADVLGCMAHGEGGLRSGPAANREWASAFGRLESGDIAGGVRELAAERLKWMSSPALLVRAARHYEGAEQILIRQAVMSSCQFVTVCPVELPPLGHWVQVACPARLDLSGGWSDTPPITYEHGGAVVDVAVLVDGCRPIGARVRRIAEPELRLASLGGTPWGEAAVELVCRELGHLENYCQPHAPGALLKAAFICTQIVQFPSQKPLRDQLMENFGGGFEVHTWSRLPHGSGLGTSSILAGAVMAALYRAAGKVAGTESLIHAVLHLEQRLTTGGGWQDQVGGLVPGIKIGRSEARLPLRVEVEEILVPEGFARILSDHLLLVYTGKTRLARNLLQDVVRNWYARLPSIVQNADALVNNAEECARALRQGNLPLIGKCLDVYWQQKKCMAPGCEPLAVGRMMDALQPYVYGQCLAGAGGGGFLYVLTKEPQQKETLHQILAKTEGLGNFSIHSIEVDTGGFSMEVVGCDPNSSTHSGEDMAM", "length": 1085, "header": "tr|A0A8V0ZU17-1|A0A8V0ZU17_CHICK Isoform 1 of L-fucose kinase OS=Gallus gallus OX=9031 GN=FUK PE=1 SV=1 CANONICAL=A0A8V0ZU17-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZU17-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU17/entry#A0A8V0ZU17-1", "sequence": { "sequence": "MAAGVEWTAIVLTCRRGGGVAALQRELELRRRRGALGRRPVLVLALEDPWAGVGSGGATLNAVLVAAEHLSARAGCTVVSADALKEARILILHTGREFSFDDCGRAFTCLPAEQPRAAAEALVCNLDSLLGTVTQRLCVGSPPGVWVCSTDMLLSVPSVPGIDWDGFQGVRVIAVPGSQAYARNHGVYLADEQGLVRDIIYKGTETQIQQCAGPDGTVPLVCGVVFFSSSAAEQLLATHVIPPLDACTYMGLDSGAPPIQLSLFFDIVLSMAGGMTEEDFVKGGGDASVRSARSVLWTALRAFPLSMACIPDASYDYLTTAASDHIRSLTLLPSSTSHLRFCKTAHSHVDQPLLLEDGSSVTNCLLEGAVRLAAGSVIQHCHLQGPLEIGPGCLLTGLTVDSSPALQGCPLRDVVLQGHHVRLRDLPCRVFTLTGRLDDWQSPAEEATYLNISWAEFFHRTGIRKGDLWDAETPQKDRCLLSARLFPVLHASEALGLEDVLWLLAPAVSGERLARWRAAWRMSWQELLPCLDKAAELGARRDLFFLQGQHKVQCVLLGRQDGSLLPLIRSAVHEGYHEALLGTLDEVASTADDAGIAARALACIADVLGCMAHGEGGLRSGPAANREWASAFGRLESGDIAGGVRELAAERLKWMSSPALLVRAARHYEGAEQILIRQAVMSSCQFVTVCPVELPPLGHWVQVACPARLDLSGGWSDTPPITYEHGGAVVDVAVLVDGCRPIGARVRRIAEPELRLASLGGTPWGEAAVELVCRELGHLENYCQPHAPGALLKAAFICTQIVQFPSQKPLRDQLMENFGGGFEVHTWSRLPHGSGLGTSSILAGAVMAALYRAAGKVAGTESLIHAVLHLEQRLTTGGGWQDQVGGLVPGIKIGRSEARLPLRVEVEEILVPEGFARILSDHLLLVYTGKTRLARNLLQDVVRNWYARLPSIVQNADALVNNAEECARALRQGNLPLIGKCLDVYWQQKKCMAPGCEPLAVGRMMDALQPYVYGQCLAGAGGGGFLYVLTKEPQQKETLHQILAKTEGLGNFSIHSIEVDTGGFSMEVVGCDPNSSTHSGEDMAM", "length": 1085, "header": "tr|A0A8V0ZU17-1|A0A8V0ZU17_CHICK Isoform 1 of L-fucose kinase OS=Gallus gallus OX=9031 GN=FUK PE=1 SV=1 CANONICAL=A0A8V0ZU17-1" }, "locus": { "chromosome": "11", "start_pos": 1794563, "end_pos": 1787823, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056589.1", "url": "https://www.ensembl.org/id/ENSGALT00010056589.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034331.1", "url": "https://www.ensembl.org/id/ENSGALP00010034331.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:770049", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:770049", "resource": "KEGG Pathway" }, { "id": "R-GGA-6787639", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6787639", "resource": "Reactome", "description": "GDP-fucose biosynthesis" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2QQ86-1", "protein_name": "L-fucose kinase", "gene_name": "Fcsk", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDHPRGVDWTVIILTCQYKDSVQVFQRELEVRQKREQIPAGTLLLAVEDPQTRVGSGGATLNALLVAAEHLSARAGFTVVTSDVLHSAWILILHMGRDFPFDDCGRAFTCLPVENPQAPVEALVCNLDCLLDIMTHRLGPGSPPGVWVCSTDMLLSVPPNPGINWDGFRGTRVIAFPGSLTYALNHGVYLTDSQGFVLDIYYQGTKAELQRCVGPDGLVPLVSGVVFFSVETAEHLLATHVSPPLDACTYMGLDSGAQPVQLSLFFDILLCMARNVNRENFLAGRPPEMGQGDADVAAYLKGARAQLWRELRDQPLTMVYVPDGGYSYMTADASEFLHSLTMPGVAVAQIVHSQVEEPQLLEASCSVVSCLLEGPVYLGPRSVLQHCHLRGPIHIGAGCFVSGLDTAHSEALHGLELRDLILQGHHVRLHGSLSRAFTLVGRLDSWERQGAGMYLNMSWNEFFKKTGIRDWDLWDPDTPPSDRCLLSARLFPVLHPMRALGPQDVLWMLYPQEDRGEALRAWRASWRLSWEQLQPCLDRAATLASRRDLFFCQALQKARHVLEARQDLCLLPLIRAAVGEGCSGPLLATLDKVAAGAEDPGVAARALACVADVLGCMAEGRGGLRSGPAANPEWIQPFSYLECGDLVRGVEALAQEREKWLSRPALLVRAARHYEGAEQILIRQAVMTSQHFVSTQPVELTALGQWVVTECPARVDFSGGWSDTPPIAYELGGAVLGLAVRVDGCRPIGAKARRIREPELRLAVGPRQDEMTMKMVCRSLDDLQDYCQPHAPGALLKAAFICSGIVHIHSEIPLCEQLLHSFNGGFELHTWSELPHGSGLGTSSILAGAALAALQRAAGRAVGTEALIHAVLHLEQVLTTGGGWQDQVSGLMPGIKVGRSRAHLPLKVEVEEITVPEGFVQKINDHLLLVYTGKTRLARNLLQDVLRNWYARLPAVVQNARRLVRQTEKCAEAFRQGNLPLLGQYLTSYWEQKKLMAPGCEPLAVRRMMDILAPHVYGQSLAGAGGGGFLYLLTKEPRQKEALEAVLAKAEGLGNYSVHLVEVDTQGLSLQLLGSDMYLCGAGPSEAGNT", "length": 1090 }, "evidence": [ { "id": "A0A8V0ZU17", "url": "https://omabrowser.org/oma/group/A0A8V0ZU17/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0ABK0LNN2-1", "protein_name": "L-fucose kinase", "gene_name": "Fcsk", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLAAPAAASTRAESCRRRHHRRRRLPRPDPLASRLSCPPASGSPSILARMDQPKGVNWTVIILTCQYKDSVQVFQRELEVRQKREQIPAGTMLLAVEDPQTRVGSGGATLNALLVAAEHLSARAGFTVVTSDVLHSAWILILHMGRDFPFDDCGRAFTCLPVENPQAPVEALVCNLDCLLDIMTHRLGPGSPPGVWVCSTDMLLSVPPNPGISWDGFRGTRVIAFPGSLAYALNHGVYLTDSQGVVLDIYYQGTKAEIQRCVRPDGLVPLVSGVVFFSVETAEHLLATHVSPPLDACTYMGLDSGAQPVQLSLFFDILLCMARNMSRENFVAGRPPEMGQGDPDVARYLKGARAQLWRELRDQPLTMVYVPDGGYSYMTTDATEFLHRLTMPGVAVAQIVHSQVEEPQLLEATCSVVSCLLEGPVHLGPRSVLQHCHLRGPIHIGAGCFVSGLDTAHSEALHGLELHDLILQGHHIRLHGSQSRVFTLAGRLDSWERQGAGMYLNMSWNEFFKKTGIRDWDLWDPDTPLSDRCLLSARLFPVLHPTRALGPQDVLWMLHPHKDRGEALRAWRASWRLSWEQLQPRLDRAATLDFRRDLFFRQALQKARHVLEARQDLCLHPLIRAAVGEGCSGPLLATLDKVAAGAEDPGVAARALACVADVLGCMAEGQGGLRSGPAANPEWIQPFSYLERGDLMRGVEALAQEREKWLTRPALLVRAARHYEGAEQILIRQAVMTARHFVSTQPVELPAPGQWVVTECPARVDFSGGWSDTPPIAYELGGAVLGLAVRVDGRRPIGAKARRILEPELWLAVGPRQDEMTVKIVCRSLDDLQDYCQPHAPGALLKAAFICADIVHVNSEVPLHEQLLRSFNGGFELHTWSELPHGSGLGTSSILAGAALAALQRAAGRTVGTEALIHAVLHLEQVLTTGGGWQDQVSGLMPGIKVGRSRAQLPLKVEVEEITVPENFVQRINDHLLLVYTGKTRLARNLLQDVLRNWYARLPVVVQNARRLVRQTEKCAEAFRQGNLALLGQYLTSYWEQKKLMAPGCEPLAVHRMMDVLAPYAFGQSLAGAGGGGFLYLLTKEPRQKEVLEAVLAKVEGLGNYSVHLVQVDTQGLSLQLLGHDAHLCGAGPSEVGNT", "length": 1139 }, "evidence": [ { "id": "A0A8V0ZU17", "url": "https://omabrowser.org/oma/group/A0A8V0ZU17/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "I3LTC2-1", "protein_name": "L-fucose kinase", "gene_name": "FCSK", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEQPKGVDWTVIILTCQYKDSVEVFQKELEIRQKREQIPASTLLLAVEDPEVHVGSGGATLNALLVAAEHLSARAGFTVVTSDVLHSAWILILHMGRDFPFDDCGRAFTCLPVENPQAPVEAVVCNLDCLLDIMSHRLGPGSPPGVWVCSTDMLLSVPPNPGINWDGFRGARVIALPGSTAYARNHGVYLTDSQGFVLDIYYQGTEAEIQRCARPDGQVPLVSGIVFFSVETAEHLLATHVSPPLDACTYMGLDSGAQPVQLSLFFDILLCMARNVRREDFLVGRPPEMGRGDMETEGYLRGARAELWRELRDQPLTLAYVPDGSYNYMTNSASEFLHSLTFPGASGAQVVHSQVEEQQLLGAGSSVVSCLLEGPVQLGPGSVLQHCHLRGPIHIGTGCFVSGLDAAQSEALHSLELHDLVLQGHHLQLHGAPSRAFTLVGRLDSWERQGAGTYLNMSWSKFFQKTGIRDWDLWDPDTPPTERCLLSARLFPVLHPLRALGPQDMLWMLDPQEDGGKALRAWRDSWRLSWEQLQPCLDRAATLASRRDLFFRQALHKARHVLEARQDLSLRPLIRAAVREGCPGPLMATLDQVAAGAGDPGVAARALACVADILGCMAEGRGGLRSGPAANPEWVRPFSYLECGDLAGGVEALAQEREKWLSRPALLVRAARHYEGAGQILIRQAVMSAQHFVSTEPVELPAPGQWVVAECPARVDFSGGWSDTPPLAYEHGGAVLGLAVRVDGRRPIGARARRIPEPELWLAVGPQHDKMAMKIVCRSLDDLQDYCQPHAPGALLKAAFICAGILSVHSELSLSEQLLCTFGGGFELQTWSELPHGSGLGTSSILAGAALAALQRVAGRAVGTEALIHAVLHLEQVLTTGGGWQDQVGGLMPGIKVGRSRAQLPLKVEVEEITVPAGFVQKLNDHLLLVYTGKTRLARNLLQDVLRSWYARLPPVVQNAHNLVQQTEECAEAFRQGSLPRLGQCLTSYWEQKKLMAPGCEPLAVRHMMDALAPHVHGQSLAGAGGGGFLYLLTKEPRQKEALEAVLAKTEGLGNYSVHLVEVDTQGLSLQLLGTETSTGCSF", "length": 1083 }, "evidence": [ { "id": "A0A8V0ZU17", "url": "https://omabrowser.org/oma/group/A0A8V0ZU17/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q55DE9-1", "protein_name": "Fucokinase", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNFHSYQHNYIGENKNLNENGEEDIYWDAIAVTAPKYEHAEEFLKELQNRQNEGIISKKTFLISIPDPYINTGYRPMKTKRRSKSQEEIDDEEEQETFGEIPLQYQSSNNKNKNDNNNNNKNEKHKIYHNHGIKNNIDDNGDEIDENEENLHKPHYTKVGSGSSMINSLFVITEKLSALSGKSYLDVDILKNKRILLLLNGGIHQHAPLVNLCTKSFSMMPLKNIDIIKHHQNQNKQQQDGQNKNEKSNKKYVGDEPVYPIDILLSNLNDIVLNLQSGFMVSSTESLIFFNREDSNLKSKTLWKQSGVSVITMNVGPDYYTNHGMCKINEETGEILEIAYKKPKEYLQVNGFISKNDDTASIYTGIIFFCEKTTEKLLYLHNTSPLDSCTYLGVDSGSQLLKFGVFPDILCSMTKNETFESYLNQPYFYGSHKSLVRKARKVVWDSFRTTPIRSIKIKGTYYYLKNPTDYLNFINSNIGVGASGEKSIISKKMHSFIDCQDSVKGIIVNSILMGKGKSFDTTVIYDSILTGNWSIGERSIVFGVKSLFETFHIHSNMMVNEIRLKSIKIKHSISESPKALIVLGIEDDLNSFYNDPTARIANRNWEEFLLSSGVSPDELWSKGVPKILRTARLFPIIVNDQDEKMYEASLWIQNKESPPLSVIGRWRSSKRISVADIIGESYLLDYTQLEVKQQVQQLSENKVGDGVLIVENSNSNNCNNNNNNNINNNNNNINNNINNNNDNDNNIDINNNNNNNNNNNNNNNNNNNLNNSNENCYSFNTNNLVDNIISNSERIKPCTTSFTTGASEYSSKWMIEGDIEAGFKWRREISFQVDSMEIEHILVQGIDQSILPFVKKWSECNIPLSKALETLDRISLSCPLQYTGRLLSCISDTLAIYVNNQGGLRSGPARNSQFEKSFNYFRNHDERKGFLSLIKERRKWLTSYESMIRVARHYEGAGQIVIKNIVDTCPTELKPLDPSNSPTTTTTTTKDWICVSLPVRIDLAGGWTDTPPICYEHGGVVLNAAIRIRGKKSIEARVRRLDEPVLIFRVGQTGDSIICRSLNDLMDYDQPHAPGSLLKSCFLQLGLIDYGDGINFNNVSSVDGRKAKTITTSTTTACVVVCKTLKQQLESLGGGMEVTSSSDLPTGSGLGTSSILAAGLITAMAYAYGYKYSDQHLFHAVLKVEQMLTTGGGWQDQIGGVLGGFKEGSCTRFHSKSDKIMVTANQLPMSDQTIQTINDHLLLIYTGRTRLARDLLQDVIRRWYAKTQEILSNTEALIQTTKTMKEALIRGDIKEIGSCLLQYWNQKKAMAVGSEPTRIVQIFNLVKDYTYGYSLAGAGGGGFMILITKDHCTVTKNKLQEIIGKVDGLESVEIFDTEIDTNGLEISIEKHVEYLQVPPMNVTN", "length": 1404 }, "evidence": [ { "id": "A0A8V0ZU17", "url": "https://omabrowser.org/oma/group/A0A8V0ZU17/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q7TMC8-1", "protein_name": "L-fucose kinase", "gene_name": "Fcsk", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEQSEGVNWTVIILTCQYKDSVQVFQRELEVRQRREQIPAGTMLLAVEDPQTRVGSGGATLNALLVAAEHLSARAGFTVVTSDVLHSAWILILHMGRDFPFDDCGRAFTCLPVENPQAPVEALVCNLDCLLDIMTHRLGPGSPPGVWVCSTDMLLSVPPNPGISWDGFRGARVIAFPGSLAYALNHGVYLTDSQGLVLDIYYQGTKAEIQRCVGPDGLVPLVSGVVFFSVETAEHLLATHVSPPLDACTYMGLDSGAQPVQLSLFFDILLCMARNMSRENFLAGRPPELGQGDMDVASYLKGARAQLWRELRDQPLTMVYVPDGGYSYMTTDATEFLHRLTMPGVAVAQIVHSQVEEPQLLEATCSVVSCLLEGPVHLGPRSVLQHCHLRGPIRIGAGCFVSGLDTAHSEALHGLELHDVILQGHHVRLHGSLSRVFTLAGRLDSWERQGAGMYLNMSWNEFFKKTGIRDWDLWDPDTPPSDRCLLTARLFPVLHPTRALGPQDVLWMLHPRKHRGEALRAWRASWRLSWEQLQPCVDRAATLDFRRDLFFCQALQKARHVLEARQDLCLRPLIRAAVGEGCSGPLLATLDKVAAGAEDPGVAARALACVADVLGCMAEGRGGLRSGPAANPEWIQPFSYLECGDLMRGVEALAQEREKWLTRPALLVRAARHYEGAEQILIRQAVMTARHFVSTQPVELPAPGQWVVTECPARVDFSGGWSDTPPIAYELGGAVLGLAVRVDGRRPIGAKARRIPEPELWLAVGPRQDEMTMRIVCRSLDDLRDYCQPHAPGALLKAAFICAGIVHLHSELPLLEQLLHSFNGGFELHTWSELPHGSGLGTSSILAGAALAALQRAAGRAVGTEALIHAVLHLEQVLTTGGGWQDQVSGLMPGIKVGRSRAQLPLKVEVEEITVPEGFVQKINDHLLLVYTGKTRLARNLLQDVLRNWYARLPVVVQNARRLVRQTEKCAEAFRQGNLPLLGQYLTSYWEQKKLMAPGCEPLAVQRMMDVLAPYAYGQSLAGAGGGGFLYLLTKEPRQKETLEAVLAKAEGLGNYSVHLVEVDPQGLSLQLLGHDTRLCGAGPSEVGTT", "length": 1090 }, "evidence": [ { "id": "A0A8V0ZU17", "url": "https://omabrowser.org/oma/group/A0A8V0ZU17/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8N0W3-1", "protein_name": "L-fucose kinase", "gene_name": "FCSK", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEQPKGVDWTVIILTCQYKDSVQVFQRELEVRQKREQIPAGTLLLAVEDPEKRVGSGGATLNALLVAAEHLSARAGFTVVTSDVLHSAWILILHMGRDFPFDDCGRAFTCLPVENPEAPVEALVCNLDCLLDIMTYRLGPGSPPGVWVCSTDMLLSVPANPGISWDSFRGARVIALPGSPAYAQNHGVYLTDPQGLVLDIYYQGTEAEIQRCVRPDGRVPLVSGVVFFSVETAERLLATHVSPPLDACTYLGLDSGARPVQLSLFFDILHCMAENVTREDFLVGRPPELGQGDADVAGYLQSARAQLWRELRDQPLTMAYVSSGSYSYMTSSASEFLLSLTLPGAPGAQIVHSQVEEQQLLAAGSSVVSCLLEGPVQLGPGSVLQHCHLQGPIHIGAGCLVTGLDTAHSKALHGRELRDLVLQGHHTRLHGSPGHAFTLVGRLDSWERQGAGTYLNVPWSEFFKRTGVRAWDLWDPETLPAEYCLPSARLFPVLHPSRELGPQDLLWMLDHQEDGGEALRAWRASWRLSWEQLQPCLDRAATLASRRDLFFRQALHKARHVLEARQDLSLRPLIWAAVREGCPGPLLATLDQVAAGAGDPGVAARALACVADVLGCMAEGRGGLRSGPAANPEWMRPFSYLECGDLAAGVEALAQERDKWLSRPALLVRAARHYEGAGQILIRQAVMSAQHFVSTEQVELPGPGQWVVAECPARVDFSGGWSDTPPLAYELGGAVLGLAVRVDGRRPIGARARRIPEPELWLAVGPRQDEMTVKIVCRCLADLRDYCQPHAPGALLKAAFICAGIVHVHSELQLSEQLLRTFGGGFELHTWSELPHGSGLGTSSILAGTALAALQRAAGRVVGTEALIHAVLHLEQVLTTGGGWQDQVGGLMPGIKVGRSRAQLPLKVEVEEVTVPEGFVQKLNDHLLLVYTGKTRLARNLLQDVLRSWYARLPAVVQNAHSLVRQTEECAEGFRQGSLPLLGQCLTSYWEQKKLMAPGCEPLTVRRMMDVLAPHVHGQSLAGAGGGGFLYLLTKEPQQKEALEAVLAKTEGLGNYSIHLVEVDTQGLSLKLLGTEASTCCPFP", "length": 1084 }, "evidence": [ { "id": "A0A8V0ZU17", "url": "https://omabrowser.org/oma/group/A0A8V0ZU17/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9LNJ9-1", "protein_name": "Bifunctional fucokinase/GDP-fucose pyrophosphorylase", "gene_name": "FKGP", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSKQRKKADLATVLRKSWYHLRLSVRHPTRVPTWDAIVLTAASPEQAELYDWQLRRAKRMGRIASSTVTLAVPDPDGKRIGSGAATLNAIYALARHYEKLGFDLGPEMEVANGACKWVRFISAKHVLMLHAGGDSKRVPWANPMGKVFLPLPYLAADDPDGPVPLLFDHILAIASCARQAFQDQGGLFIMTGDVLPCFDAFKMTLPEDAASIVTVPITLDIASNHGVIVTSKSESLAESYTVSLVNDLLQKPTVEDLVKKDAILHDGRTLLDTGIISARGRAWSDLVALGCSCQPMILELIGSKKEMSLYEDLVAAWVPSRHDWLRTRPLGELLVNSLGRQKMYSYCTYDLQFLHFGTSSEVLDHLSGDASGIVGRRHLCSIPATTVSDIAASSVILSSEIAPGVSIGEDSLIYDSTVSGAVQIGSQSIVVGIHIPSEDLGTPESFRFMLPDRHCLWEVPLVGHKGRVIVYCGLHDNPKNSIHKDGTFCGKPLEKVLFDLGIEESDLWSSYVAQDRCLWNAKLFPILTYSEMLKLASWLMGLDDSRNKEKIKLWRSSQRVSLEELHGSINFPEMCNGSSNHQADLAGGIAKACMNYGMLGRNLSQLCHEILQKESLGLEICKNFLDQCPKFQEQNSKILPKSRAYQVEVDLLRACGDEAKAIELEHKVWGAVAEETASAVRYGFREHLLESSGKSHSENHISHPDRVFQPRRTKVELPVRVDFVGGWSDTPPWSLERAGYVLNMAITLEGSLPIGTIIETTNQMGISIQDDAGNELHIEDPISIKTPFEVNDPFRLVKSALLVTGIVQENFVDSTGLAIKTWANVPRGSGLGTSSILAAAVVKGLLQISNGDESNENIARLVLVLEQLMGTGGGWQDQIGGLYPGIKFTSSFPGIPMRLQVVPLLASPQLISELEQRLLVVFTGQVRLAHQVLHKVVTRYLQRDNLLISSIKRLTELAKSGREALMNCEVDEVGDIMSEAWRLHQELDPYCSNEFVDKLFEFSQPYSSGFKLVGAGGGGFSLILAKDAEKAKELRQRLEEHAEFDVKVYNWSICI", "length": 1055 }, "evidence": [ { "id": "A0A8V0ZU17", "url": "https://omabrowser.org/oma/group/A0A8V0ZU17/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "GDP-L-fucose salvage", "id": "GO:0042352", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042352", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZU17", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU17" } ], "pmid": "" }, { "name": "carbohydrate phosphorylation", "id": "GO:0046835", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046835", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZU17", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU17" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "fucokinase activity", "id": "GO:0050201", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050201", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZU17", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU17" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZU17", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU17" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1051, "end_pos": 1053, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1074, "end_pos": 1076, "annotation": "n_glycosylation_sequon" }, { "start_pos": 451, "end_pos": 453, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "13241", "name": "", "equation": "beta-L-fucose + ATP = beta-L-fucose 1-phosphate + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZU17-1" ], "evidence": [ { "id": "13241", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/13241" } ] }, { "id": "R-GGA-6787540", "name": "FCSK phosphorylates beta-Fuc to Fuc1P", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-ALL-6787678" ], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZU17-1" ], "evidence": [ { "id": "R-GGA-6787540", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6787540" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-6787678", "participant_name": "beta-Fuc [cytosol]", "crossref": [ { "id": "42589", "database": "ChEBI", "url": "" }, { "id": "G85196CF", "database": "GlyTouCan", "url": "" }, { "id": "ZINC000001532813", "database": "ZINC", "url": "" }, { "id": "HMDB0059625", "database": "HMDB Metabolite", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0ZU17", "gene_name": "FUK", "activity": [ { "ec_number": "2.7.1.52", "activity": "L-fucose + ATP = beta-L-fucose 1-phosphate + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZU17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU17" } ] }, { "ec_number": "2.7.1.52", "activity": "", "evidence": [ { "id": "A0A8V0ZU17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU17" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZU17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU17" }, { "id": "PF07959", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07959" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "GDP-fucose pyrophosphorylase", "eco_id": "ECO_0000259", "start_pos": 82, "end_pos": 490, "start_aa": "Asp", "end_aa": "His", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZU17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU17" }, { "id": "PF08544", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08544" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "GHMP kinase C-terminal", "eco_id": "ECO_0000259", "start_pos": 968, "end_pos": 1043, "start_aa": "Arg", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZU17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU17" }, { "id": "PF00288", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00288" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "GHMP kinase N-terminal", "eco_id": "ECO_0000259", "start_pos": 813, "end_pos": 884, "start_aa": "Gln", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.7.1.52", "ec_name": "L-fucose + ATP = beta-L-fucose 1-phosphate + ADP + H(+).", "evidence": [ { "id": "2.7.1.52", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.52" }, { "id": "2.7.1.52", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.7.1.52" } ] } ], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1051, "end_pos": 1053 }, { "start_pos": 1074, "end_pos": 1076 }, { "start_pos": 451, "end_pos": 453 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", 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"https://www.ebi.ac.uk/interpro/entry/IPR057724", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZU31", "url": "https://www.orthodb.org/?gene=A0A8V0ZU31", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A3H8", "url": "https://www.orthodb.org/?gene=A0A8V1A3H8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14611", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14611", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14611:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14611:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07773", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07773", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25752", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25752", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-5620912", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5620912", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZU31", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU31", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZU31-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU31-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A3H8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3H8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A3H8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3H8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAAGLGVLLLLLLLAAPCAGQRHGEPVFQPSFIHMSGLRVNSFFLGDSSGVNFYIVVGAIDKDTGNVRVPICSGSERVGDWDLSVTPDVGASKVTVTFTRSLQLCLSNATDCCTAPLCVVETLQVLACSGSVMLAHLLIQAEIYANSSFTGNVSEDMSVIPNQVFQPLGSCPCDLTDGACDVRCCCDPECTPDLKQLFDGLCFSGVFGGDVNPPFDQLCSTQTTEYTPDWFPLLCVQSSLNNTPFLGYFYDGSISAPRVPPFRIPVQASPGKLFTGYRPGDPIMTEDDEYFTIPQSLAGHCVRNAPVAYLQDLDVKCLSEAASYKEGLPHDVRINSGTGDFIQQNVIYRTVTDVGKFITKSEGLPTAGLPCQKVTFAEHYAFIWEDDNIEGVNVTVFLGSLCDGETLTQRFTAEFVSLRSDSATEVPKNPGYRVGNVVRAANMNASDTAGSLRIWQPAGRGLCTSAAHTPVVFGVDSFSGCILEVDVNENCSLLRGNVTEKLNSLIQATHVGKRRNSNDSNLNDWVKIIRLDPNISASPGDLKGICPDVPASLNIRIIFAAVGAVQGIPREEILAVQISYSTVIWQFQCSLSCENTASLLPITAAVQFIRVPAQPPVPMTRFQINYTEFDCERNDVCWPQLLYPLTRFYTGEPYSRRLAAGLALAFLAVLAAVMGSPCFSQVWEKFSV", "length": 689, "header": "tr|A0A8V0ZU31-1|A0A8V0ZU31_CHICK Isoform 1 of Tectonic family member 2 OS=Gallus gallus OX=9031 GN=TCTN2 PE=3 SV=1 CANONICAL=A0A8V0ZU31-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZU31-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU31/entry#A0A8V0ZU31-1", "sequence": { 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Transcript", "id": "ENSGALT00010060281.1", "url": "https://www.ensembl.org/id/ENSGALT00010060281.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010037040.1", "url": "https://www.ensembl.org/id/ENSGALP00010037040.1" } ] } }, { "isoform_ac": "A0A8V1A3H8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU31/entry#A0A8V1A3H8-1", "sequence": { "sequence": "MKETFFQPSFIHMSGLRVNSFFLGDSSGVNFYIVVGAIDKDTGNVRVPICSGSERVGDWDLSVTPDVGASKVTVTFTRSLQLCLSNATDCCTAPLCVVETLQVLACSGSVMLAHLLIQAEIYANSSFTGNVSEDMSVIPNQVFQPLGSCPCDLTDGACDVRCCCDPECTPDLKQLFDGLCFSGVFGGDVNPPFDQLCSTQTTEYTPDWFPLLCVQSSLNNTPFLGYFYDGSISAPRVPPFRIPVQASPGKLFTGYRPGDPIMTEDDEYFTIPQQSLAGHCVRNAPVAYLQDLDVKCLSEAASYKEGLPHDVRINSGTGDFIQQNVIYRTVTDVGKFITKSEGLPTAGLPCQKVTFAEHYAFIWEDDNIEGVNVTVFLGSLCDGETLTQRFTAEFVSLRSDSATEVPKNPGYRVGNVVRAANMNASDTAGSLRIWQPAGRGLCTSAAHTPVVFGVDSFSGCILEVDVNENCSLLRGNVTEKLNSLIQATHVGKRRNSNDSNLNDWVKIIRLDPNISASPGDLKGICPDVPASLNIRIIFAAVGAVQGIPREEILAVQISYSTVIWQFQCSLSCENTASLLPITAAVQFIRVPAQPPVPMTRFQINYTEFDCERNDVCWPQLLYPLTRFYTGEPYSRRLAAGLALAFLAVLAAVMGSPCFSQVWEKFSV", "length": 667, "header": "tr|A0A8V1A3H8-1|A0A8V0ZU31_CHICK Computationally mapped isoform of Tectonic family member 2 OS=Gallus gallus OX=9031 GN=TCTN2 PE=3 SV=1 CANONICAL=A0A8V0ZU31-1" }, "locus": { "chromosome": "15", "start_pos": 4955529, "end_pos": 4946026, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010060284.1", "url": "https://www.ensembl.org/id/ENSGALT00010060284.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010037043.1", "url": "https://www.ensembl.org/id/ENSGALP00010037043.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-5620912", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5620912", "resource": "Reactome", "description": "Anchoring of the basal body to the plasma membrane" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "cilium assembly", "id": "GO:0060271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060271", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZU31", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU31" } ], "pmid": "" }, { "name": "smoothened signaling pathway", "id": "GO:0007224", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007224", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZU31", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU31" } ], "pmid": "" }, { "name": "protein localization to ciliary transition zone", "id": "GO:1904491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904491", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZU31", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU31" } ], "pmid": "" }, { "name": "cell projection organization", "id": "GO:0030030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030030", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZU31", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU31" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "MKS complex", "id": "GO:0036038", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036038", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZU31", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU31" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 109, "end_pos": 111, "annotation": "n_glycosylation_sequon" }, { "start_pos": 147, "end_pos": 149, "annotation": "n_glycosylation_sequon" }, { "start_pos": 153, "end_pos": 155, "annotation": "n_glycosylation_sequon" }, { "start_pos": 242, "end_pos": 244, "annotation": "n_glycosylation_sequon" }, { "start_pos": 394, "end_pos": 396, "annotation": "n_glycosylation_sequon" }, { "start_pos": 445, "end_pos": 447, "annotation": "n_glycosylation_sequon" }, { "start_pos": 491, "end_pos": 493, "annotation": "n_glycosylation_sequon" }, { "start_pos": 498, "end_pos": 500, "annotation": "n_glycosylation_sequon" }, { "start_pos": 519, "end_pos": 521, "annotation": "n_glycosylation_sequon" }, { "start_pos": 535, "end_pos": 537, "annotation": "n_glycosylation_sequon" }, { "start_pos": 626, "end_pos": 628, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZU31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU31" }, { "id": "PF07773", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07773" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Tectonic-1-3", "eco_id": "ECO_0000259", "start_pos": 276, "end_pos": 418, "start_aa": "Thr", "end_aa": "Ser", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZU31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU31" }, { "id": "PF25752", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25752" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Tectonic-1-3 N-terminal", "eco_id": "ECO_0000259", "start_pos": 147, "end_pos": 256, "start_aa": "Asn", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 109, "end_pos": 111 }, { "start_pos": 147, "end_pos": 149 }, { "start_pos": 153, "end_pos": 155 }, { "start_pos": 242, "end_pos": 244 }, { "start_pos": 394, "end_pos": 396 }, { "start_pos": 445, "end_pos": 447 }, { "start_pos": 491, "end_pos": 493 }, { "start_pos": 498, "end_pos": 500 }, { "start_pos": 519, "end_pos": 521 }, { "start_pos": 535, "end_pos": 537 }, { "start_pos": 626, "end_pos": 628 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZU40-1", "uniprot_ac": "A0A8V0ZU40", "uniprot_id": "A0A8V0ZU40_CHICK", "mass": { "chemical_mass": 9623.0, "monoisotopic_mass": 9623.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": 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U12-type introns comprises less than 1% of all non-coding sequences. 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[ { "id": "A0A8V0ZU58", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZU58", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd12238", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12238", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12239", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12239", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034147", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034147", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045164", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045164", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZU53", "url": "https://www.orthodb.org/?gene=A0A8V0ZU53", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZU58", "url": "https://www.orthodb.org/?gene=A0A8V0ZU58", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16105", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16105", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16105:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16105:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00076", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00076", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-72165", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72165", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZU53", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU53", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZU53-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU53-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZU58", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU58", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZU58-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU58-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRLAPPARLLRCERQLLISRDLWYCRRFRRRAAMAATGSEEERTGGAALGAGLCHLGVARRRGRTLLVRHLPAELTVAEKEDLLQHFGAVAVRVLSDHGRLKHTAFATFPSENAAVKALSRLHQLKLLGHTLVVEFAKEQDSMQVLNQPSFSDKYKSSEEPVKEEKRETSCLKIENGIAPSHGLTFPINSCLKYLYPPPSSTILANIANALASVPKFYVQVLHLMNKMNLPPPFGPITTRPPMYEEYLPVPVPPPPIPPLPPEEPPLPEEEEEQISSGDESEYESDNEEEKERMTKLMELATLQPKRPINTKKRGVRKKQRIKDLLNVPTCTPHSNLHPTLSPSDVFEQPQYVGLKKIEFHITTDIPSVLQINLEREEKNDLYATTEEINHTGFGRIFPTPSSNDKMETEEEDDEIPSEFISRRELEKNRLSREEMEKFSVFKNYEPGEPNCRIYVKNLAKQVQEKDLKFIFGRYVDFQSVLERNMFDIRLMKEGRMKGQAFIGLPNEKAAAKALKEANGYVLFEKPMVVQFARSARPKQDSNEVKRKK", "length": 549, "header": "tr|A0A8V0ZU58-1|A0A8V0ZU58_CHICK Isoform 1 of RNA-binding region-containing protein 3 OS=Gallus gallus OX=9031 GN=RNPC3 PE=4 SV=1 CANONICAL=A0A8V0ZU58-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZU53-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU58/entry#A0A8V0ZU53-1", "sequence": { "sequence": "MAATGSEEERTGGAALGAGLCHLGVARRRGRTLLVRHLPAELTVAEKEDLLQHFGAVAVRVLSDHGRLKHTAFATFPSENAAVKALSRLHQLKLLGHTLVVEFAKEQDSMQVLNQPSFSDKYKSSEEPVKEEKRETSCLKIENGIAPSHGLTFPINSCLKYLYPPPSSTILANIANALASVPKFYVQVLHLMNKMNLPPPFGPITTRPPMYEEYLPVPVPPPPIPPLPPEEPPLPEEEEEQISSGDESEYESDNEEEKERMTKLMELATLQPKRPINTKKRGVRKKQRIKDLLNVPTCTPHSNLHPTLSPSDVFEQPQYVGLKKIEFHITTDIPSVLQINLEREEKNDLYATTEEINHTGFGRIFPTPSSNDKMETEEEDDEIPSEFISRRELEKNRLSREEMEKFSVFKNYEPGEPNCRIYVKNLAKQVQEKVCKQEKLNIYQKGFLAASLNQPFNSRISSSFLEDMLTSSQYWNEICKLK", "length": 482, "header": "tr|A0A8V0ZU53-1|A0A8V0ZU58_CHICK Computationally mapped isoform of RNA-binding region-containing protein 3 OS=Gallus gallus OX=9031 GN=RNPC3 PE=4 SV=1 CANONICAL=A0A8V0ZU58-1" }, "locus": { "chromosome": "8", "start_pos": 10817293, "end_pos": 10808782, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056629.1", "url": "https://www.ensembl.org/id/ENSGALT00010056629.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034371.1", "url": "https://www.ensembl.org/id/ENSGALP00010034371.1" } ] } }, { "isoform_ac": "A0A8V0ZU58-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU58/entry#A0A8V0ZU58-1", "sequence": { "sequence": "MRLAPPARLLRCERQLLISRDLWYCRRFRRRAAMAATGSEEERTGGAALGAGLCHLGVARRRGRTLLVRHLPAELTVAEKEDLLQHFGAVAVRVLSDHGRLKHTAFATFPSENAAVKALSRLHQLKLLGHTLVVEFAKEQDSMQVLNQPSFSDKYKSSEEPVKEEKRETSCLKIENGIAPSHGLTFPINSCLKYLYPPPSSTILANIANALASVPKFYVQVLHLMNKMNLPPPFGPITTRPPMYEEYLPVPVPPPPIPPLPPEEPPLPEEEEEQISSGDESEYESDNEEEKERMTKLMELATLQPKRPINTKKRGVRKKQRIKDLLNVPTCTPHSNLHPTLSPSDVFEQPQYVGLKKIEFHITTDIPSVLQINLEREEKNDLYATTEEINHTGFGRIFPTPSSNDKMETEEEDDEIPSEFISRRELEKNRLSREEMEKFSVFKNYEPGEPNCRIYVKNLAKQVQEKDLKFIFGRYVDFQSVLERNMFDIRLMKEGRMKGQAFIGLPNEKAAAKALKEANGYVLFEKPMVVQFARSARPKQDSNEVKRKK", "length": 549, "header": "tr|A0A8V0ZU58-1|A0A8V0ZU58_CHICK Isoform 1 of RNA-binding region-containing protein 3 OS=Gallus gallus OX=9031 GN=RNPC3 PE=4 SV=1 CANONICAL=A0A8V0ZU58-1" }, "locus": { "chromosome": "8", "start_pos": 10817392, "end_pos": 10806523, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056634.1", "url": "https://www.ensembl.org/id/ENSGALT00010056634.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034376.1", "url": "https://www.ensembl.org/id/ENSGALP00010034376.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 400, "start_aa": "Thr", "end_pos": 400, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr400", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-GGA-72165", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72165", "resource": "Reactome", "description": "mRNA Splicing - Minor Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZU58", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU58" } ], "pmid": "" }, { "name": "pre-mRNA intronic binding", "id": "GO:0097157", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097157", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZU58", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU58" } ], "pmid": "" }, { "name": "U12 snRNA binding", "id": "GO:0030626", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030626", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZU58", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU58" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZU58", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU58" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZU58", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU58" } ], "pmid": "" }, { "name": "U12-type spliceosomal complex", "id": "GO:0005689", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005689", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZU58", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU58" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "mRNA splicing, via spliceosome", "id": "GO:0000398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000398", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZU58", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU58" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 390, "end_pos": 392, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZU58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU58" }, { "id": "PS50102", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50102" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RRM", "eco_id": "ECO_0000259", "start_pos": 64, "end_pos": 139, "start_aa": "Arg", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 400 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 390, "end_pos": 392 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZU54-1", "uniprot_ac": "A0A8V0ZU54", "uniprot_id": "A0A8V0ZU54_CHICK", "mass": { "chemical_mass": 63211.0, "monoisotopic_mass": 63211.0 }, "refseq": { "ac": "XP_015149804", "name": "extracellular serine/threonine protein kinase FAM20C", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015149804" }, "gene_names": [ { "name": "FAM20C", "type": "recommended", "evidence": [ { "id": "A0A8V0ZU54", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU54" } ] }, { "name": "FAM20C", "type": "synonym", "evidence": [ { "id": "XP_015149804", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015149804" } ] } ], "protein_names": [ { "name": "FAM20C golgi associated secretory pathway kinase", "type": "synonym", "evidence": [ { "id": "A0A8V0ZU54", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU54/entry#names_and_taxonomy" } ] }, { "name": "extracellular serine/threonine protein kinase FAM20C", "type": "synonym", "evidence": [ { "id": "XP_015149804", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015149804" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052545.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015149804.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015149804", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015149804" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZU54", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU54" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FAM20C", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU54", "locus": { "chromosome": "14", "start_pos": 1790836, "end_pos": 1738288, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022117", "url": "https://www.ensembl.org/id/ENSGALG00010022117" } ] } } ], "crossref": [ { "id": "A0A8V0ZU54", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZU54", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd10471", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd10471", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "416445", "url": "https://www.ncbi.nlm.nih.gov/gene/416445", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR009581", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009581", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024869", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024869", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416445", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416445", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RQNEDNE", "url": "https://omabrowser.org/oma/group/RQNEDNE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZU54", "url": "https://www.orthodb.org/?gene=A0A8V0ZU54", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12450", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12450", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12450:SF11", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12450:SF11", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06702", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06702", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-381426", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-381426", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-8957275", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8957275", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015149804", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015149804", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZU54", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU54", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZU54-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU54-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKMLLVRKFRVLILMVFLVACTMHIMIDLLPRLERRGAEGRPGCSCPPPAAPPRAAPRWPSKHTLRILQDFSAEPASNLSSQSREAAERAAGGGGDAAAAAAAAGGEGAAAGRPRRLIAPGAPRPPPPAHAAPLAALFQHPLYRAALPPLADGDLLFNVNSDIRFNPRAAEQGEWHNEENEEFLPTGETSIDSYPNWLKFHIGINRYELYSRHNPAIEALLQDLVSQKITSVAMKSGGTQLKLIMTFQNYGQALFKPMKQTREQETPPDFFYFSDYERHNAEIAAFHLDRILDFRRVPPVAGRLVNMTREIRDVTRDKKLWRTFFISPANNICFYGECSYYCSTEHALCGKPDQIEGSLAAFLPDLSLAKRKTWRNPWRRSYHKRKKAEWEVDPDYCEEVKQTPPYDSGTRILDIMDMTVFDFLMGNMDRHHYETFEKFGNETFIIHLDNGRGFGKYSHDELSILVPLNQCCRIRKSTYLRLQLLAKEEYKLSLLMKESLLKDKIAPILYQPHLEAMDRRLRIVLKAVSDCIEKDGYDNVVENDFNTDVNTVATER", "length": 556, "header": "tr|A0A8V0ZU54-1|A0A8V0ZU54_CHICK Isoform 1 of FAM20C golgi associated secretory pathway kinase OS=Gallus gallus OX=9031 GN=FAM20C PE=1 SV=1 CANONICAL=A0A8V0ZU54-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZU54-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU54/entry#A0A8V0ZU54-1", "sequence": { "sequence": "MKMLLVRKFRVLILMVFLVACTMHIMIDLLPRLERRGAEGRPGCSCPPPAAPPRAAPRWPSKHTLRILQDFSAEPASNLSSQSREAAERAAGGGGDAAAAAAAAGGEGAAAGRPRRLIAPGAPRPPPPAHAAPLAALFQHPLYRAALPPLADGDLLFNVNSDIRFNPRAAEQGEWHNEENEEFLPTGETSIDSYPNWLKFHIGINRYELYSRHNPAIEALLQDLVSQKITSVAMKSGGTQLKLIMTFQNYGQALFKPMKQTREQETPPDFFYFSDYERHNAEIAAFHLDRILDFRRVPPVAGRLVNMTREIRDVTRDKKLWRTFFISPANNICFYGECSYYCSTEHALCGKPDQIEGSLAAFLPDLSLAKRKTWRNPWRRSYHKRKKAEWEVDPDYCEEVKQTPPYDSGTRILDIMDMTVFDFLMGNMDRHHYETFEKFGNETFIIHLDNGRGFGKYSHDELSILVPLNQCCRIRKSTYLRLQLLAKEEYKLSLLMKESLLKDKIAPILYQPHLEAMDRRLRIVLKAVSDCIEKDGYDNVVENDFNTDVNTVATER", "length": 556, "header": "tr|A0A8V0ZU54-1|A0A8V0ZU54_CHICK Isoform 1 of FAM20C golgi associated secretory pathway kinase OS=Gallus gallus OX=9031 GN=FAM20C PE=1 SV=1 CANONICAL=A0A8V0ZU54-1" }, "locus": { "chromosome": "14", "start_pos": 1789945, "end_pos": 1738487, 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"UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZU60-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU60-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEKLAAHGLDGCTLRWVKHWLDGRAQRVVVNGAASSWRPVTSAVPQGSVLGPLLFKTFTDDVDGGIECTLSEFADDSKLGGSVDLPEGRRALQRDLDRRDRWAQVNGTSFNRGKCWVLHFGHNKRRQAYRLGEVWLQSCLMERDVGVLLDSRLNMSQQCARVAKKANGILAWIRNGVVSRTREVILVLREMI", "length": 192, "header": "tr|A0A8V0ZU60-1|A0A8V0ZU60_CHICK Isoform 1 of Reverse transcriptase domain-containing protein OS=Gallus gallus OX=9031 GN=LOC107057295 PE=4 SV=1 CANONICAL=A0A8V0ZU60-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZU60-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU60/entry#A0A8V0ZU60-1", "sequence": { "sequence": "MEKLAAHGLDGCTLRWVKHWLDGRAQRVVVNGAASSWRPVTSAVPQGSVLGPLLFKTFTDDVDGGIECTLSEFADDSKLGGSVDLPEGRRALQRDLDRRDRWAQVNGTSFNRGKCWVLHFGHNKRRQAYRLGEVWLQSCLMERDVGVLLDSRLNMSQQCARVAKKANGILAWIRNGVVSRTREVILVLREMI", "length": 192, "header": "tr|A0A8V0ZU60-1|A0A8V0ZU60_CHICK Isoform 1 of Reverse transcriptase domain-containing protein OS=Gallus gallus OX=9031 GN=LOC107057295 PE=4 SV=1 CANONICAL=A0A8V0ZU60-1" }, "locus": { "chromosome": "20", "start_pos": 1759788, "end_pos": 1759213, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010060312.1", "url": "https://www.ensembl.org/id/ENSGALT00010060312.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010037071.1", "url": "https://www.ensembl.org/id/ENSGALP00010037071.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 106, "end_pos": 108, "annotation": "n_glycosylation_sequon" }, { "start_pos": 154, "end_pos": 156, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], 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"A0A8V0ZU65_CHICK", "mass": { "chemical_mass": 84179.0, "monoisotopic_mass": 84179.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Ligand dependent nuclear receptor interacting factor 1", "type": "synonym", "evidence": [ { "id": "A0A8V0ZU65", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU65/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZU65", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU65" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU65", "locus": {} } ], "crossref": [ { "id": "A0A8V0ZU65", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZU65", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR026191", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026191", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZU65", "url": "https://www.orthodb.org/?gene=A0A8V0ZU65", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZZD1", "url": "https://www.orthodb.org/?gene=A0A8V0ZZD1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16131", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16131", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16131:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16131:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15741", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15741", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZU65", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU65", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZU65-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU65-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZZD1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZD1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZZD1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZD1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPGAHRRVGSASGRVRRCRVEGAALPIAGCMYRVVQTTGPDGKNLLKLLPISKSSGNFVPIVQSSAMSNNPKVNVSSPVHLAFKTQLASTAAPSSVKIPVFQSPNSGKIILARTLDKQEGFKAGSDKESLTTESAADIQSSCVSVDRQSLQNAAVTSSSEQSHTAHMSVKTKDNPISVKPPVLPSGHHLQIPADAEVKSVPASFLPASIQQKILAAAATNVTDGADSKKMPTVIYVSPVNTVKTALPKCLQAVDHKPAPDVSKTLLMTAPQKAHSSSPETGMSDGQQCQHTPMKWIVRESPQLPAPCLIPVKSSNNVASKILKTLSDMKNVEVNSANILPLCSSGSGVSQTKITSIKDNALVMYNGKVYLLTRRGSDVLSAQADMQASSSYSASLKKGTSKLIDSTEVTKISSKVVNLVLSKSKGMPLPQKDPKVCSNSKVSSSGGLRNDLKSTSAALVTPSAEEQSSTVNRGKSLPFMESISSGMTPITAVGMQETTYQDDKEMIHSSKAASAVLPQSEHECAFSEDWQKVQCKKMYSVGKVNQIRDQEKPHWKQYLQLRRKFGLYKEERVYLKRIPLTTSCEKPDERLCSSNSLERKNDSCPSSSLDVTITDQHQECIEEEKAILNLEEGLSKKRKTKSSLPDSGKRRRTSVKSATSSSTEDSSPSSITHNRSVSPPPALSQQSISTDFISSTDAEREPSSQNSDVTDSDIPVLVSCEDHASLFEGSFRNDTFPLTPPDLDETIRDEKIKRLKQLLREREAALEEMRKKNAANLKY", "length": 778, "header": "tr|A0A8V0ZU65-1|A0A8V0ZU65_CHICK Isoform 1 of Ligand dependent nuclear receptor interacting factor 1 OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0ZU65-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZU65-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU65/entry#A0A8V0ZU65-1", "sequence": { "sequence": "MPGAHRRVGSASGRVRRCRVEGAALPIAGCMYRVVQTTGPDGKNLLKLLPISKSSGNFVPIVQSSAMSNNPKVNVSSPVHLAFKTQLASTAAPSSVKIPVFQSPNSGKIILARTLDKQEGFKAGSDKESLTTESAADIQSSCVSVDRQSLQNAAVTSSSEQSHTAHMSVKTKDNPISVKPPVLPSGHHLQIPADAEVKSVPASFLPASIQQKILAAAATNVTDGADSKKMPTVIYVSPVNTVKTALPKCLQAVDHKPAPDVSKTLLMTAPQKAHSSSPETGMSDGQQCQHTPMKWIVRESPQLPAPCLIPVKSSNNVASKILKTLSDMKNVEVNSANILPLCSSGSGVSQTKITSIKDNALVMYNGKVYLLTRRGSDVLSAQADMQASSSYSASLKKGTSKLIDSTEVTKISSKVVNLVLSKSKGMPLPQKDPKVCSNSKVSSSGGLRNDLKSTSAALVTPSAEEQSSTVNRGKSLPFMESISSGMTPITAVGMQETTYQDDKEMIHSSKAASAVLPQSEHECAFSEDWQKVQCKKMYSVGKVNQIRDQEKPHWKQYLQLRRKFGLYKEERVYLKRIPLTTSCEKPDERLCSSNSLERKNDSCPSSSLDVTITDQHQECIEEEKAILNLEEGLSKKRKTKSSLPDSGKRRRTSVKSATSSSTEDSSPSSITHNRSVSPPPALSQQSISTDFISSTDAEREPSSQNSDVTDSDIPVLVSCEDHASLFEGSFRNDTFPLTPPDLDETIRDEKIKRLKQLLREREAALEEMRKKNAANLKY", "length": 778, "header": "tr|A0A8V0ZU65-1|A0A8V0ZU65_CHICK Isoform 1 of Ligand dependent nuclear receptor interacting factor 1 OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0ZU65-1" }, "locus": { "chromosome": "26", "start_pos": 1125213, "end_pos": 1116082, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010060317.1", "url": "https://www.ensembl.org/id/ENSGALT00010060317.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010037076.1", "url": "https://www.ensembl.org/id/ENSGALP00010037076.1" } ] } }, { "isoform_ac": "A0A8V0ZZD1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU65/entry#A0A8V0ZZD1-1", "sequence": { "sequence": "MYRVVQTTGPDGKNLLKLLPISKSSGNFVPIVQSSAMSNNPKVNVSSPVHLAFKTQLASTAAPSSVKIPVFQSPNSGKIILARTLDKQEGFKAGSDKESLTTESAADIQSSCVSVDRQSLQNAAVTSSSEQSHTAHMSVKTKDNPISVKPPVLPSGHHLQIPADAEVKSVPASFLPASIQQKILAAAATNVTDGADSKKMPTVIYVSPVNTVKTALPKCLQAVDHKPAPDVSKTLLMTAPQKAHSSSPETGMSDGQQCQHTPMKWIVRESPQLPAPCLIPVKSSNNVASKILKTLSDMKNVEVNSANILPLCSSGSGVSQTKITSIKDNALVMYNGKVYLLTRRGSDVLSAQADMQASSSYSASLKKGTSKLIDSTEVTKISSKVVNLVLSKSKGMPLPQKDPKVCSNSKVSSSGGLRNDLKSTSAALVTPSAEEQSSTVNRGKSLPFMESISSGMTPITAVGMQETTYQDDKEMIHSSKAASAVLPQSEHECAFSEDWQKVQCKKMYSVGKVNQIRDQEKPHWKQYLQLRRKFGLYKEERVYLKRIPLTTSCEKPDERLCSSNSLERKNDSCPSSSLDVTITDQHQECIEEEKAILNLEEGLSKKRKTKSSLPDSGKRRRTSVKSATSSSTEDSSPSSITHNRSVSPPPALSQQSISTDFISSTDAEREPSSQNSDVTDSDIPVLVSCEDHASLFEGSFRNDTFPLTPPDLDETIRDEKIKRLKQLLREREAALEEMRKKNAANLKY", "length": 748, "header": "tr|A0A8V0ZZD1-1|A0A8V0ZU65_CHICK Computationally mapped isoform of Ligand dependent nuclear receptor interacting factor 1 OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0ZU65-1" }, "locus": { "chromosome": "26", "start_pos": 1120739, "end_pos": 1116082, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010060319.1", "url": "https://www.ensembl.org/id/ENSGALT00010060319.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010037078.1", "url": "https://www.ensembl.org/id/ENSGALP00010037078.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 460, "start_aa": "Thr", "end_pos": 460, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr460", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZU65", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU65" } ], "pmid": "" }, { "name": "chromosome, telomeric region", "id": "GO:0000781", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000781", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZU65", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU65" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZU65", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU65" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "nuclear retinoic acid receptor binding", "id": "GO:0042974", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042974", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZU65", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU65" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 220, "end_pos": 222, "annotation": "n_glycosylation_sequon" }, { "start_pos": 600, "end_pos": 602, "annotation": "n_glycosylation_sequon" }, { "start_pos": 673, "end_pos": 675, "annotation": "n_glycosylation_sequon" }, { "start_pos": 732, "end_pos": 734, "annotation": "n_glycosylation_sequon" }, { "start_pos": 74, "end_pos": 76, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": 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"url": "https://www.ensembl.org/id/ENSGALP00010035118.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", 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}, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZU72-1", "uniprot_ac": "A0A8V0ZU72", "uniprot_id": "A0A8V0ZU72_CHICK", "mass": { "chemical_mass": 13140.0, "monoisotopic_mass": 13140.0 }, "refseq": { "ac": "NP_001180192", "name": "cell cycle exit and neuronal differentiation protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001180192" }, "gene_names": [ { "name": "CEND1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZU72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU72" } ] }, { "name": "CEND1", "type": "synonym", "evidence": [ { "id": "NP_001180192", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001180192" } ] } ], "protein_names": [ { "name": "Cell cycle exit and neuronal differentiation 1", "type": "synonym", "evidence": [ { "id": "A0A8V0ZU72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU72/entry#names_and_taxonomy" } ] }, { "name": "cell cycle exit and neuronal differentiation protein 1", "type": "synonym", "evidence": [ { "id": "NP_001180192", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001180192" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR13267659.195106.1, ERR2368565.178137.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992323, SAMEA103992393 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000212.1. On Nov 18, 2021 this sequence version replaced NP_001180192.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001180192", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001180192" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZU72", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU72" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CEND1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU72", "locus": {} } ], "crossref": [ { "id": "A0A8V0ZU72", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZU72", "database": "AlphaFoldDB", "categories": [] }, { "id": "770044", "url": "https://www.ncbi.nlm.nih.gov/gene/770044", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR020162", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020162", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:770044", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:770044", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WSCENLN", "url": "https://omabrowser.org/oma/group/WSCENLN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR36683", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR36683", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR36683:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR36683:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15677", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15677", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001180192", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001180192", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZU72", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU72", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZU72-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU72-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDSKGNVRSANKPDAKAPSSGKSEKPSPGPATNADKKETPKEQPNPATAPKKAGSDAAVVNNHSNLKPSAAATETQEATGQSPDSDHKGNGSEESPGSIFDNMKPLIIVGGVAVAALAVIVGVAFLARKK", "length": 130, "header": "tr|A0A8V0ZU72-1|A0A8V0ZU72_CHICK Isoform 1 of Cell cycle exit and neuronal differentiation 1 OS=Gallus gallus OX=9031 GN=CEND1 PE=4 SV=1 CANONICAL=A0A8V0ZU72-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZU72-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU72/entry#A0A8V0ZU72-1", "sequence": { "sequence": "MDSKGNVRSANKPDAKAPSSGKSEKPSPGPATNADKKETPKEQPNPATAPKKAGSDAAVVNNHSNLKPSAAATETQEATGQSPDSDHKGNGSEESPGSIFDNMKPLIIVGGVAVAALAVIVGVAFLARKK", "length": 130, "header": "tr|A0A8V0ZU72-1|A0A8V0ZU72_CHICK Isoform 1 of Cell cycle exit and neuronal differentiation 1 OS=Gallus gallus OX=9031 GN=CEND1 PE=4 SV=1 CANONICAL=A0A8V0ZU72-1" }, "locus": { "chromosome": "5", "start_pos": 640696, "end_pos": 640307, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053827.1", "url": "https://www.ensembl.org/id/ENSGALT00010053827.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032403.1", "url": "https://www.ensembl.org/id/ENSGALP00010032403.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:770044", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:770044", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "G3I3G9-1", "protein_name": "Cell cycle exit and neuronal differentiation protein 1", "gene_name": "Cend1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": 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"annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZU77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU77" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 170, "end_pos": 239, "start_aa": "Pro", "end_aa": "His", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 235, "end_pos": 237 } ] }, 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"glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": 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"publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZU97-1", "uniprot_ac": "A0A8V0ZU97", "uniprot_id": "A0A8V0ZU97_CHICK", "mass": { "chemical_mass": 249778.0, "monoisotopic_mass": 249778.0 }, "refseq": {}, "gene_names": [ { "name": "SPAG17", "type": "recommended", "evidence": [ { "id": "A0A8V0ZU97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU97" } ] } ], "protein_names": [ { "name": "Sperm associated antigen 17", "type": "synonym", "evidence": [ { "id": "A0A8V0ZU97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU97/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZU97", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU97" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SPAG17", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU97", "locus": { "chromosome": "1", "start_pos": 79153089, "end_pos": 79061263, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022138", "url": "https://www.ensembl.org/id/ENSGALG00010022138" } ] } } ], "crossref": [ { "id": "418315", "url": "https://www.ncbi.nlm.nih.gov/gene/418315", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026173", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026173", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "HYATVIT", "url": "https://omabrowser.org/oma/group/HYATVIT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZLV6", "url": "https://www.orthodb.org/?gene=A0A8V0ZLV6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZLW1", "url": "https://www.orthodb.org/?gene=A0A8V0ZLW1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZNN5", "url": "https://www.orthodb.org/?gene=A0A8V0ZNN5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZNP1", "url": "https://www.orthodb.org/?gene=A0A8V0ZNP1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZU97", "url": "https://www.orthodb.org/?gene=A0A8V0ZU97", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21963", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21963", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21963:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21963:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14874", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14874", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZLV6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLV6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLV6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLV6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLW1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLW1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLW1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLW1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZNN5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNN5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZNN5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNN5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZNP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNP1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZNP1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNP1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZU97", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU97", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZU97-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU97-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVDEKLDASKHHVLAAWKANGIMGCIKRGLASREREVIVHLYSAVLCQDLGPPAQERGGAVGEGPEEDMKMIRGLQHLFCEERQRKLGLFSLEKRLQGDIMVFLRVKASLQESWVVEVAKAILDSGEEIPVTLTGKLLKFQLLCIKQKDLQRRASEKAEEQKKEKNGGKEKGKPLGKEKPPSAKATEKERKGKKTETAPPVPDTVKKNTQLKRRGEKEEEYTYIDDEPDDGAHYYFIILGFHNLQLLPVMSELGVYVSSVIRISSENYEPLQTYLEATRFQEESLLSPEDVEAEKIKKNESIKDLETFWKYLEPVLNNGKHGSRLLDVARLHHLVKENAFPSDWSDREILLAFGTELFESIACLMYDCIDWRRQHCNYLESTKFINVPELSESKSTQPPVVTKIPPASQVTSSKKKQQAEEVLTTVIFSQEEEFSFMATSMDMRYYNDLLNQIPEECFSVPIMLNCMLEQVIASEENLTPPSLVVPEERADGIHHKIADHIASVLPSLPLSESEKKNLYDYFSPKYSEETVTPKYPLLFNYHDTLAQRLQLLKIQGNLNPKKIEHEMMDKLPLKELISFTLPSAENDTKRLARVHELMHYCTSELLSWAEVERAFRVFTFESLRLTELSDSGLLESSGSLVGGDSEVSCIPWDNPAKFARQLRQLFLMEMKLTGKSPGGSGHAETNDKDERDGLPDSVLSKELDLSTSDLVSLENYGLEPKLEEIKKTQKRCLTDWNFAEHFHPDVLLQVLHTAAQEYRCIDSYYHTQDKSLLVVLHNPMNQNRLCQETWDVALHSNVGFRNYLELVASSIEDWVKEEEVKYQEEKMAREIKALKQGEGMTEGPSEFSNYAVKKPGLSMNATNSTSRSESIMDTILESQSINEISAFIREGSLKASKEKENQLLEEERLQKEKEAKKENLSGKMKRQEVVTREESEGSNKKTSREKLKDEPAKVPEPEEDPSTPETHSEKIYKFLGYNTGENVIQVSGINHYLFPSDGGQIQVEKIEFVKGLTLVKVKVVKDNHNFFIHITDPKKNLTEIEVHENNQEQKIAPGKIKNQKKAVSKFGSFSATLENGIQLSLSYYGPTGKTADDETDPVLAAILNVPSVHVLTVPPSTTSASGKKDKSVKQKSGKSLPSTKSSNSRISSSPPDNHEKQEGKVEVEEPASQTQVMSAALAFRSLNVSCPNGLVLTFLGESFEDLEGAATTAEATEDEVEKGEVRTDKVREEEVEEGQTKMDEAKEEEAEKDEAKGNEAKEEKAVESEEKEHEVIEGEIKQEDTKREKTKQPALKILVRQSYPQKVKNSRLYASVTSQIKQEVSRVITSQGTVVRYMMDGSTWVLFADGTVSRSPDSGPVLPPPVIPESMQPLSEPEPLPEMDTKRGKGSDKNIVLHPKEEVFEDIIQGIVNPEQPKENQAGTWITTTPLGIQVGTEGGRQMDLEPILLYQATDPADGTIMTVRDDEVIIVEKLDGSRVVDHADGTRITTFYQACEEHLVPQHSKKTGELSETIARKAKCIRVENPKFATVTTNCEDGTCCTIFGDGTSIIAKPQGTYQVLPVKAGSLFIDEDCSAVYTHEVCNSTIEKEGSQAGRYIMKHTSSTICEMMDPEGNLFKVMADGSTSVLVQSTGFDNKENESSTSLLPEVNKSISYDEHVPRFFIIHMDGSGTELLRSKDVEAYLAEACGDPAVAVLQEPVQEYPGAVSITTLFPLSEVSPWVMKKEPECIVPPNLQPRTWNAFSPCEKETTVRTHIWKGLCIGSKEETCLPVPVRKCPKKLQVRQLFQYEPLSDELREKLHLSLKKYIENILRQEDELEEMNLKEPRTEEEKEDAANLLDLVKSFPNWEKSSEDLSAKAHITELYERAVVSQCPLRTEKRVTEKTADQQQSFSTEEQTPVSKWQNKLQEHRKELDEGKETLMAIRNKTIPPYFESELGKAFLSKKFPDVEALSKELPPVPQKESGNLPPETIKNLRRESECLSSMSDSSPSPSLLLQTHSVQREDSSSTADPSLAVESQEAPFQVKVQSLLVNAAGQPRKEKVRLPSSLLGRKPNSIPHKKVEDPVAGRVNISSLATAKQHLSGFHLIPPQMMFGVLKEGCTYAATVVLKNVGINFSRFRVKQPPPYTGLSVMYTPGPVAAGLQVELEIEIFAMPIGGESTNGLEEISHDIEIITETETLLLPVRATVLRSEIFECRPQGYPQGGMAAAVRAVSTSPRPRVRITLPRKLSS", "length": 2228, "header": "tr|A0A8V0ZU97-1|A0A8V0ZU97_CHICK Isoform 1 of Sperm associated antigen 17 OS=Gallus gallus OX=9031 GN=SPAG17 PE=4 SV=1 CANONICAL=A0A8V0ZU97-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZLV6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU97/entry#A0A8V0ZLV6-1", "sequence": { "sequence": "MPFYVFSLYVPFFCSLSLTIFSLKKKGEKNENKTGALGKRVVEVAKAILDSGEEIPVTLTGKLLKFQLLCIKQKDLQRRASEKAEEQKKEKNGGKEKGKPLGKEKPPSAKATEKERKGKKTETAPPVPDTVKKNTQLKRRGEKEEEYTYIDDEPDDGAHYYFIILGFHNLQLLPVMSELGVYVSSVIRISSENYEPLQTYLEATRFQEESLLSPEDVEAEKIKKNESIKDLETFWKYLEPVLNNGKHGSRLLDVARLHHLVKENAFPSDWSDREILLAFGTELFESIACLMYDCIDWRRQHCNYLESTKFINVPELSESKSTQPPVVTKIPPASQVTSSKKKQQAEEVLTTVIFSQEEEFSFMATSMDMRYYNDLLNQIPEECFSVPIMLNCMLEQVIASEENLTPPSLVVPEERADGIHHKIADHIASVLPSLPLSESEKKNLYDYFSPKYSEETVTPKYPLLFNYHDTLAQRLQLLKIQGNLNPKKIEHEMMDKLPLKELISFTLPSAENDTKRLARVHELMHYCTSELLSWAEVERAFRVFTFESLRLTELSDSGLLESSGSLVGGDSEVSCIPWDNPAKFARQLRQLFLMEMKLTGKSPGGSGHAETNDKDERDGLPDSVLSKELDLSTSDLVSLENYGLEPKLEEIKKTQKRCLTDWNFAEHFHPDVLLQVLHTAAQEYRCIDSYYHTQDKSLLVVLHNPMNQNRLCQETWDVALHSNVGFRNYLELVASSIEDWVKEEEVKYQEEKMAREIKALKQGEGMTEGPSEFSNYAVKKPGLSMNATNSTSRSESIMDTILESQSINEISAFIREGSLKASKEKENQLLEEERLQKEKEAKKENLSGKMKRQEVVTREESEGSNKKTSREKLKDEPAKVPEPEEDPSTPETHSEKIYKFLGYNTGENVIQVSGINHYLFPSDGGQIQVEKIEFVKGLTLVKVKVVKDNHNFFIHITDPKKNLTEIEVHENNQEQKIAPGKIKNQKKAVSKFGSFSATLENGIQLSLSYYGPTGKTADDETDPVLAAILNVPSVHVLTVPPSTTSASGKKDKSVKQKSGKSLPSTKSSNSRISSSPPDNHEKQEGKVEVEEPASQTQVMSAALAFRSLNVSCPNGLVLTFLGESFEDLEGAATTAEATEDEVEKGEVRTDKVREEEVEEGQTKMDEAKEEEAEKDEAKGNEAKEEKAVESEEKEHEVIEGEIKQEDTKREKTKQPALKILVRQSYPQKVKNSRLYASVTSQIKQEVSRVITSQGTVVRYMMDGSTWVLFADGTVSRSPDSGPVLPPPVIPESMQPLSEPEPLPEMDTKRGKGSDKNIVLHPKEEVFEDIIQGIVNPEQPKENQAGTWITTTPLGIQVGTEGGRQMDLEPILLYQATDPADGTIMTVRDDEVIIVEKLDGSRVVDHADGTRITTFYQACEEHLVPQHSKKTGELSETIARKAKCIRVENPKFATVTTNCEDGTCCTIFGDGTSIIAKPQGTYQVLPVKAGSLFIDEDCSAVYTHEVCNSTIEKEGSQAGRYIMKHTSSTICEMMDPEGNLFKVMADGSTSVLVQSTGFDNKENESSTSLLPEVNKSISYDEHVPRFFIIHMDGSGTELLRSKDVEAYLAEACGDPAVAVLQEPVQEYPGAVSITTLFPLSEVSPWVMKKEPECIVPPNLQPRTWNAFSPCEKETTVRTHIWKGLCIGSKEETCLPVPVRKCPKKLQVRQLFQYEPLSDELREKLHLSLKKYIENILRQEDELEEMNLKEPRTEEEKEDAANLLDLVKSFPNWEKSSEDLSAKAHITELYERAVVSQCPLRTEKRVTEKTADQQQSFSTEEQTPVSKWQNKLQEHRKELDEGKETLMAIRNKTIPPYFESELGKAFLSKKFPDVEALSKELPPVPQKESGNLPPETIKNLRRESECLSSMSDSSPSPSLLLQTHSVQREDSSSTADPSLAVESQEAPFQVKVQSLLVNAAGQPRKEKVRLPSSLLGRKPNSIPHKKVEDPVAGRVNISSLATAKQHLSGFHLIPPQMMFGVLKEGCTYAATVVLKNVGINFSRFRVKQPPPYTGLSVMYTPGPVAAGLQVELEIEIFAMPIGGESTNGLEEISHDIEIITETETLLLPVRATVLRSEIFECRPQGYPQGGMAAAVRAVSTSPRPRVRITLPRKLSS", "length": 2154, "header": "tr|A0A8V0ZLV6-1|A0A8V0ZLV6_CHICK Computationally mapped isoform of Sperm associated antigen 17 OS=Gallus gallus OX=9031 GN=SPAG17 PE=4 SV=1 CANONICAL=A0A8V0ZU97-1" }, "locus": { "chromosome": "1", "start_pos": 79150694, "end_pos": 79075257, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053863.1", "url": "https://www.ensembl.org/id/ENSGALT00010053863.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032429.1", "url": "https://www.ensembl.org/id/ENSGALP00010032429.1" } ] } }, { "isoform_ac": "A0A8V0ZLW1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU97/entry#A0A8V0ZLW1-1", "sequence": { "sequence": "MAPKRAKAGGAAAAAAASSAGTAAKSWEAELVSAPLEEDDWKPSIAFVVGAKIEDEIHTQALSLAVQLPLRKLFSVVTREDIFRQIAESGSQKGKKVKDVPMFYEVVEVAKAILDSGEEIPVTLTGKLLKFQLLCIKQKDLQRRASEKAEEQKKEKNGGKEKGKPLGKEKPPSAKATEKERKGKKTETAPPVPDTVKKNTQLKRRGEKEEEYTYIDDEPDDGAHYYFIILGFHNLQLLPVMSELGVYVSSVIRISSENYEPLQTYLEATRFQEESLLSPEDVEAEKIKKNESIKDLETFWKYLEPVLNNGKHGSRLLDVARLHHLVKENAFPSDWSDREILLAFGTELFESIACLMYDCIDWRRQHCNYLESTKFINVPELSESKSTQPPVVTKIPPASQVTSSKKKQQAEEVLTTVIFSQEEEFSFMATSMDMRYYNDLLNQIPEECFSVPIMLNCMLEQVIASEENLTPPSLVVPEERADGIHHKIADHIASVLPSLPLSESEKKNLYDYFSPKYSEETVTPKYPLLFNYHDTLAQRLQLLKIQGNLNPKKIEHEMMDKLPLKELISFTLPSAENDTKRLARVHELMHYCTSELLSWAEVERAFRVFTFESLRLTELSDSGLLESSGSLVGGDSEVSCIPWDNPAKFARQLRQLFLMEMKLTGKSPGGSGHAETNDKDERDGLPDSVLSKELDLSTSDLVSLENYGLEPKLEEIKKTQKRCLTDWNFAEHFHPDVLLQVLHTAAQEYRCIDSYYHTQDKSLLVVLHNPMNQNRLCQETWDVALHSNVGFRNYLELVASSIEDWVKEEEVKYQEEKMAREIKALKQGEGMTEGPSEFSNYAVKKPGLSMNATNSTSRSESIMDTILESQSINEISAFIREGSLKASKEKENQLLEEERLQKEKEAKKENLSGKMKRQEVVTREESEGSNKKTSREKLKDEPAKVPEPEEDPSTPETHSEKIYKFLGYNTGENVIQVSGINHYLFPSDGGQIQVEKIEFVKGLTLVKVKVVKDNHNFFIHITDPKKNLTEIEVHENNQEQKIAPGKIKNQKKAVSKFGSFSATLENGIQLSLSYYGPTGKTADDETDPVLAAILNVPSVHVLTVPPSTTSASGKKDKSVKQKSGKSLPSTKSSNSRISSSPPDNHEKQEGKVEVEEPASQTQVMSAALAFRSLNVSCPNGLVLTFLGESFEDLEGAATTAEATEDEVEKGEVRTDKVREEEVEEGQTKMDEAKEEEAEKDEAKGNEAKEEKAVESEEKEHEVIEGEIKQEDTKREKTKQPALKILVRQSYPQKVKNSRLYASVTSQIKQEVSRVITSQGTVVRYMMDGSTWVLFADGTVSRSPDSGPVLPPPVIPESMQPLSEPEPLPEMDTKRGKGSDKNIVLHPKEEVFEDIIQGIVNPEQPKENQAGTWITTTPLGIQVGTEGGRQMDLEPILLYQATDPADGTIMTVRDDEVIIVEKLDGSRVVDHADGTRITTFYQACEEHLVPQHSKKTGELSETIARKAKCIRVENPKFATVTTNCEDGTCCTIFGDGTSIIAKPQGTYQVLPVKAGSLFIDEDCSAVYTHEVCNSTIEKEGSQAGRYIMKHTSSTICEMMDPEGNLFKVMADGSTSVLVQSTGFDNKENESSTSLLPEVNKSISYDEHVPRFFIIHMDGSGTELLRSKDVEAYLAEACGDPAVAVLQEPVQEYPGAVSITTLFPLSEVSPWVMKKEPECIVPPNLQPRTWNAFSPCEKETTVRTHIWKGLCIGSKEETCLPVPVRKCPKKLQVRQLFQYEPLSDELREKLHLSLKKYIENILRQEDELEEMNLKEPRTEEEKEDAANLLDLVKSFPNWEKSSEDLSAKAHITELYERAVVSQCPLRTEKRVTEKTADQQQSFSTEEQTPVSKWQNKLQEHRKELDEGKETLMAIRNKTIPPYFESELGKAFLSKKFPDVEALSKELPPVPQKESGNLPPETIKNLRRESECLSSMSDSSPSPSLLLQTHSVQREDSSSTADPSLAVESQEAPFQVKVQSLLVNAAGQPRKEKVRLPSSLLGRKPNSIPHKKVEDPVAGRVNISSLATAKQHLSGFHLIPPQMMFGVLKEGCTYAATVVLKNVGINFSRFRVKQPPPYTGLSVMYTPGPVAAGLQVELEIEIFAMPIGGESTNGLEEISHDIEIITETETLLLPVRATVLRSEIFECRPQGYPQGGMAAAVRAVSTSPRPRVRITLPRKLSS", "length": 2219, "header": "tr|A0A8V0ZLW1-1|A0A8V0ZLW1_CHICK Computationally mapped isoform of Sperm associated antigen 17 OS=Gallus gallus OX=9031 GN=SPAG17 PE=4 SV=1 CANONICAL=A0A8V0ZU97-1" }, "locus": { "chromosome": "1", "start_pos": 79150694, "end_pos": 79061284, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053871.1", "url": "https://www.ensembl.org/id/ENSGALT00010053871.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032435.1", "url": "https://www.ensembl.org/id/ENSGALP00010032435.1" } ] } }, { "isoform_ac": "A0A8V0ZNN5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU97/entry#A0A8V0ZNN5-1", "sequence": { "sequence": "MKGEKNENKTGALGKRVVEVAKAILDSGEEIPVTLTGKLLKFQLLCIKQKDLQRRASEKAEEQKKEKNGGKEKGKPLGKEKPPSAKATEKERKGKKTETAPPVPDTVKKNTQLKRRGEKEEEYTYIDDEPDDGAHYYFIILGFHNLQLLPVMSELGVYVSSVIRISSENYEPLQTYLEATRFQEESLLSPEDVEAEKIKKNESIKDLETFWKYLEPVLNNGKHGSRLLDVARLHHLVKENAFPSDWSDREILLAFGTELFESIACLMYDCIDWRRQHCNYLESTKFINVPELSESKSTQPPVVTKIPPASQVTSSKKKQQAEEVLTTVIFSQEEEFSFMATSMDMRYYNDLLNQIPEECFSVPIMLNCMLEQVIASEENLTPPSLVVPEERADGIHHKIADHIASVLPSLPLSESEKKNLYDYFSPKYSEETVTPKYPLLFNYHDTLAQRLQLLKIQGNLNPKKIEHEMMDKLPLKELISFTLPSAENDTKRLARVHELMHYCTSELLSWAEVERAFRVFTFESLRLTELSDSGLLESSGSLVGGDSEVSCIPWDNPAKFARQLRQLFLMEMKLTGKSPGGSGHAETNDKDERDGLPDSVLSKELDLSTSDLVSLENYGLEPKLEEIKKTQKRCLTDWNFAEHFHPDVLLQVLHTAAQEYRCIDSYYHTQDKSLLVVLHNPMNQNRLCQETWDVALHSNVGFRNYLELVASSIEDWVKEEEVKYQEEKMAREIKALKQGEGMTEGPSEFSNYAVKKPGLSMNATNSTSRSESIMDTILESQSINEISAFIREGSLKASKEKENQLLEEERLQKEKEAKKENLSGKMKRQEVVTREESEGSNKKTSREKLKDEPAKVPEPEEDPSTPETHSEKIYKFLGYNTGENVIQVSGINHYLFPSDGGQIQVEKIEFVKGLTLVKVKVVKDNHNFFIHITDPKKNLTEIEVHENNQEQKIAPGKIKNQKKAVSKFGSFSATLENGIQLSLSYYGPTGKTADDETDPVLAAILNVPSVHVLTVPPSTTSASGKKDKSVKQKSGKSLPSTKSSNSRISSSPPDNHEKQEGKVEVEEPASQTQVMSAALAFRSLNVSCPNGLVLTFLGESFEDLEGAATTAEATEDEVEKGEVRTDKVREEEVEEGQTKMDEAKEEEAEKDEAKGNEAKEEKAVESEEKEHEVIEGEIKQEDTKREKTKQPALKILVRQSYPQKVKNSRLYASVTSQIKQEVSRVITSQGTVVRYMMDGSTWVLFADGTVSRSPDSGPVLPPPVIPESMQPLSEPEPLPEMDTKRGKGSDKNIVLHPKEEVFEDIIQGIVNPEQPKENQAGTWITTTPLGIQVGTEGGRQMDLEPILLYQATDPADGTIMTVRDDEVIIVEKLDGSRVVDHADGTRITTFYQACEEHLVPQHSKKTGELSETIARKAKCIRVENPKFATVTTNCEDGTCCTIFGDGTSIIAKPQGTYQVLPVKAGSLFIDEDCSAVYTHEVCNSTIEKEGSQAGRYIMKHTSSTICEMMDPEGNLFKVMADGSTSVLVQSTGFDNKENESSTSLLPEVNKSISYDEHVPRFFIIHMDGSGTELLRSKDVEAYLAEACGDPAVAVLQEPVQEYPGAVSITTLFPLSEVSPWVMKKEPECIVPPNLQPRTWNAFSPCEKETTVRTHIWKGLCIGSKEETCLPVPVRKCPKKLQVRQLFQYEPLSDELREKLHLSLKKYIENILRQEDELEEMNLKEPRTEEEKEDAANLLDLVKSFPNWEKSSEDLSAKAHITELYERAVVSQCPLRTEKRVTEKTADQQQSFSTEEQTPVSKWQNKLQEHRKELDEGKETLMAIRNKTIPPYFESELGKAFLSKKFPDVEALSKELPPVPQKESGNLPPETIKNLRRESECLSSMSDSSPSPSLLLQTHSVQREDSSSTADPSLAVESQEAPFQVKVQSLLVNAAGQPRKEKVRLPSSLLGRKPNSIPHKKVEDPVAGRVNISSLATAKQHLSGFHLIPPQMMFGVLKEGCTYAATVVLKNVGINFSRFRVKQPPPYTGLSVMYTPGPVAAGLQVELEIEIFAMPIGGESTNGLEEISHDIEIITETETLLLPVRATVLRSEIFECRPQGYPQGGMAAAVRAVSTSPRPRVRITLPRKLSS", "length": 2130, "header": "tr|A0A8V0ZNN5-1|A0A8V0ZNN5_CHICK Computationally mapped isoform of Sperm associated antigen 17 OS=Gallus gallus OX=9031 GN=SPAG17 PE=4 SV=1 CANONICAL=A0A8V0ZU97-1" }, "locus": { "chromosome": "1", "start_pos": 79150694, "end_pos": 79074963, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053865.1", "url": "https://www.ensembl.org/id/ENSGALT00010053865.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032431.1", "url": "https://www.ensembl.org/id/ENSGALP00010032431.1" } ] } }, { "isoform_ac": "A0A8V0ZNP1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU97/entry#A0A8V0ZNP1-1", "sequence": { "sequence": "MAPKRAKAGGAAAAAAASSAGTAAKSWEAELVSAPLEEDDWKPSIAFVVGAKIEDEIHTQALSLAVQLPLRKLFSVVTREDIFRQIAESGSQKGKKVKDVPMFYEVVEVAKAILDSGEEIPVTLTGKLLKFQLLCIKQKDLQRRASEKAEEQKKEKNGGKEKGKPLGKEKPPSAKATEKERKGKKTETAPPVPDTVKKNTQLKRRGEKEEEYTYIDDEPDDGAHYYFIILGFHNLQLLPVMSELGVYVSSVIRISSENYEPLQTYLEATRFQEESLLSPEDVEAEKIKKNESIKDLETFWKYLEPVLNNGKHGSRLLDVARLHHLVKENAFPSDWSDREILLAFGTELFESIACLMYDCIDWRRQHCNYLESTKFINVPELSESKSTQPPVVTKIPPASQVTSSKKKQQAEEVLTTVIFSQEEEFSFMATSMDMRYYNDLLNQIPEECFSVPIMLNCMLEQVIASEENLTPPSLVVPEERADGIHHKIADHIASVLPSLPLSESEKKNLYDYFSPKYSEETVTPKYPLLFNYHDTLAQRLQLLKIQGNLNPKKIEHEMMDKLPLKELISFTLPSAENDTKRLARVHELMHYCTSGHAETNDKDERDGLPDSVLSKELDLSTSDLVSLENYGLEPKLEEIKKTQKRCLTDWNFAEHFHPDVLLQVLHTAAQEYRCIDSYYHTQDKSLLVVLHNPMNQNRLCQETWDVALHSNVGFRNYLELVASSIEDWVKEEEVKYQEEKMAREIKALKQGEGMTEGPSEFSNYAVKKPGLSMNATNSTSRSESIMDTILESQSINEISAFIREGSLKASKEKENQLLEEERLQKEKEAKKENLSGKMKRQEVVTREESEGSNKKTSREKLKDEPAKVPEPEEDPSTPETHSEKIYKFLGYNTGENVIQVSGINHYLFPSDGGQIQVEKIEFVKGLTLVKVKVVKDNHNFFIHITDPKKNLTEIEVHENNQEQKIAPGKIKNQKKAVSKFGSFSATLENGIQLSLSYYGPTGKTADDETDPVLAAILNVPSVHVLTVPPSTTSASGKKDKSVKQKSGKSLPSTKSSNSRISSSPPDNHEKQEGKVEVEEPASQTQVMSAALAFRSLNVSCPNGLVLTFLGESFEDLEGAATTAEATEDEVEKGEVRTDKVREEEVEEGQTKMDEAKEEEAEKDEAKGNEAKEEKAVESEEKEHEVIEGEIKQEDTKREKTKQPALKILVRQSYPQKVKNSRLYASVTSQIKQEVSRVITSQGTVVRYMMDGSTWVLFADGTVSRSPDSGPVLPPPVIPESMQPLSEPEPLPEMDTKRGKGSDKNIVLHPKEEVFEDIIQGIVNPEQPKENQAGTWITTTPLGIQVGTEGGRQMDLEPILLYQATDPADGTIMTVRDDEVIIVEKLDGSRVVDHADGTRITTFYQACEEHLVPQHSKKTGELSETIARKAKCIRVENPKFATVTTNCEDGTCCTIFGDGTSIIAKPQGTYQVLPVKAGSLFIDEDCSAVYTHEVCNSTIEKEGSQAGRYIMKHTSSTICEMMDPEGNLFKVMADGSTSVLVQSTGFDNKENESSTSLLPEVNKSISYDEHVPRFFIIHMDGSGTELLRSKDVEAYLAEACGDPAVAVLQEPVQEYPGAVSITTLFPLSEVSPWVMKKEPECIVPPNLQPRTWNAFSPCEKETTVRTHIWKGLCIGSKEETCLPVPVRKCPKKLQVRQLFQYEPLSDELREKLHLSLKKYIENILRQEDELEEMNLKEPRTEEEKEDAANLLDLVKSFPNWEKSSEDLSAKAHITELYERAVVSQCPLRTEKRVTEKTADQQQSFSTEEQTPVSKWQNKLQEHRKELDEGKETLMAIRNKTIPPYFESELGKAFLSKKFPDVEALSKELPPVPQKESGNLPPETIKNLRRESECLSSMSDSSPSPSLLLQTHSVQREDSSSTADPSLAVESQEAPFQVKVQSLLVNAAGQPRKEKVRLPSSLLGRKPNSIPHKKVEDPVAGRVNISSLATAKQHLSGFHLIPPQMMFGVLKEGCTYAATVVLKNVGINFSRFRVKQPPPYTGLSVMYTPGPVAAGLQVELEIEIFAMPIGGESTNGLEEISHDIEIITETETLLLPVRATVLRSEIFECRPQGYPQGGMAAAVRAVSTSPRPRVRITLPRKLSS", "length": 2142, "header": "tr|A0A8V0ZNP1-1|A0A8V0ZNP1_CHICK Computationally mapped isoform of Sperm associated antigen 17 OS=Gallus gallus OX=9031 GN=SPAG17 PE=4 SV=1 CANONICAL=A0A8V0ZU97-1" }, "locus": { "chromosome": "1", "start_pos": 79150694, "end_pos": 79061284, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053876.1", "url": "https://www.ensembl.org/id/ENSGALT00010053876.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032437.1", "url": "https://www.ensembl.org/id/ENSGALP00010032437.1" } ] } }, { "isoform_ac": "A0A8V0ZU97-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU97/entry#A0A8V0ZU97-1", "sequence": { "sequence": "MVDEKLDASKHHVLAAWKANGIMGCIKRGLASREREVIVHLYSAVLCQDLGPPAQERGGAVGEGPEEDMKMIRGLQHLFCEERQRKLGLFSLEKRLQGDIMVFLRVKASLQESWVVEVAKAILDSGEEIPVTLTGKLLKFQLLCIKQKDLQRRASEKAEEQKKEKNGGKEKGKPLGKEKPPSAKATEKERKGKKTETAPPVPDTVKKNTQLKRRGEKEEEYTYIDDEPDDGAHYYFIILGFHNLQLLPVMSELGVYVSSVIRISSENYEPLQTYLEATRFQEESLLSPEDVEAEKIKKNESIKDLETFWKYLEPVLNNGKHGSRLLDVARLHHLVKENAFPSDWSDREILLAFGTELFESIACLMYDCIDWRRQHCNYLESTKFINVPELSESKSTQPPVVTKIPPASQVTSSKKKQQAEEVLTTVIFSQEEEFSFMATSMDMRYYNDLLNQIPEECFSVPIMLNCMLEQVIASEENLTPPSLVVPEERADGIHHKIADHIASVLPSLPLSESEKKNLYDYFSPKYSEETVTPKYPLLFNYHDTLAQRLQLLKIQGNLNPKKIEHEMMDKLPLKELISFTLPSAENDTKRLARVHELMHYCTSELLSWAEVERAFRVFTFESLRLTELSDSGLLESSGSLVGGDSEVSCIPWDNPAKFARQLRQLFLMEMKLTGKSPGGSGHAETNDKDERDGLPDSVLSKELDLSTSDLVSLENYGLEPKLEEIKKTQKRCLTDWNFAEHFHPDVLLQVLHTAAQEYRCIDSYYHTQDKSLLVVLHNPMNQNRLCQETWDVALHSNVGFRNYLELVASSIEDWVKEEEVKYQEEKMAREIKALKQGEGMTEGPSEFSNYAVKKPGLSMNATNSTSRSESIMDTILESQSINEISAFIREGSLKASKEKENQLLEEERLQKEKEAKKENLSGKMKRQEVVTREESEGSNKKTSREKLKDEPAKVPEPEEDPSTPETHSEKIYKFLGYNTGENVIQVSGINHYLFPSDGGQIQVEKIEFVKGLTLVKVKVVKDNHNFFIHITDPKKNLTEIEVHENNQEQKIAPGKIKNQKKAVSKFGSFSATLENGIQLSLSYYGPTGKTADDETDPVLAAILNVPSVHVLTVPPSTTSASGKKDKSVKQKSGKSLPSTKSSNSRISSSPPDNHEKQEGKVEVEEPASQTQVMSAALAFRSLNVSCPNGLVLTFLGESFEDLEGAATTAEATEDEVEKGEVRTDKVREEEVEEGQTKMDEAKEEEAEKDEAKGNEAKEEKAVESEEKEHEVIEGEIKQEDTKREKTKQPALKILVRQSYPQKVKNSRLYASVTSQIKQEVSRVITSQGTVVRYMMDGSTWVLFADGTVSRSPDSGPVLPPPVIPESMQPLSEPEPLPEMDTKRGKGSDKNIVLHPKEEVFEDIIQGIVNPEQPKENQAGTWITTTPLGIQVGTEGGRQMDLEPILLYQATDPADGTIMTVRDDEVIIVEKLDGSRVVDHADGTRITTFYQACEEHLVPQHSKKTGELSETIARKAKCIRVENPKFATVTTNCEDGTCCTIFGDGTSIIAKPQGTYQVLPVKAGSLFIDEDCSAVYTHEVCNSTIEKEGSQAGRYIMKHTSSTICEMMDPEGNLFKVMADGSTSVLVQSTGFDNKENESSTSLLPEVNKSISYDEHVPRFFIIHMDGSGTELLRSKDVEAYLAEACGDPAVAVLQEPVQEYPGAVSITTLFPLSEVSPWVMKKEPECIVPPNLQPRTWNAFSPCEKETTVRTHIWKGLCIGSKEETCLPVPVRKCPKKLQVRQLFQYEPLSDELREKLHLSLKKYIENILRQEDELEEMNLKEPRTEEEKEDAANLLDLVKSFPNWEKSSEDLSAKAHITELYERAVVSQCPLRTEKRVTEKTADQQQSFSTEEQTPVSKWQNKLQEHRKELDEGKETLMAIRNKTIPPYFESELGKAFLSKKFPDVEALSKELPPVPQKESGNLPPETIKNLRRESECLSSMSDSSPSPSLLLQTHSVQREDSSSTADPSLAVESQEAPFQVKVQSLLVNAAGQPRKEKVRLPSSLLGRKPNSIPHKKVEDPVAGRVNISSLATAKQHLSGFHLIPPQMMFGVLKEGCTYAATVVLKNVGINFSRFRVKQPPPYTGLSVMYTPGPVAAGLQVELEIEIFAMPIGGESTNGLEEISHDIEIITETETLLLPVRATVLRSEIFECRPQGYPQGGMAAAVRAVSTSPRPRVRITLPRKLSS", "length": 2228, "header": "tr|A0A8V0ZU97-1|A0A8V0ZU97_CHICK Isoform 1 of Sperm associated antigen 17 OS=Gallus gallus OX=9031 GN=SPAG17 PE=4 SV=1 CANONICAL=A0A8V0ZU97-1" }, "locus": { "chromosome": "1", "start_pos": 79150694, "end_pos": 79077952, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053862.1", "url": "https://www.ensembl.org/id/ENSGALT00010053862.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032428.1", "url": "https://www.ensembl.org/id/ENSGALP00010032428.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "D3ZXP4-1", "protein_name": "Sperm associated antigen 17", "gene_name": "Spag17", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAPKKEKPTGSTSYKIWEPSLIAAHMNQNDWKASIAFVVGNRIEDELPIHALNLAVQLPQRKLFSIVSWKDILQQINEIQALVGATTKKGKKTITGNLPLHYEVLLAAKTIMDNGEKLTLPLVGKLLKFQLLQIKTKDQQRRENEKKMIEERAKSEKDKGKGKSPKEKKAATVKAGKGKSKDQPEATVTVKKTTQLKRRGEDDDTKFYIDIAAENLKRENDIKELEVFWKYLEPILNNEKPETNLLDVARLHYMVKTKHFPSDWSDYEQMLDLGTEIFENVACLMYDSLDWKRQHHHYLQSMQLINVPQVVSDKTMLEAIPIPEPPPSTAPAPGKKKAQYEESHAPPSVAFIITTEVDMRYYNDLLNPIPEEFISVPLILHCMLEQVIATEEDLTPPSLVEPAPRADGLDYRIAAHIVSILPSLCLTEKEKKNLHEIFLTEGESESKTPPKGPLLLNYHDTYAHKKYALKDQKNFDPVQIEEEMQSKLPLWEFLQFPLPPPWNSTKRLATIHELMHFCTNEVLSWNEVERAFKVFTFESLKLSEVDEAGRLKPTEVISETNVENVNIPWDNPARFAKLIRQRYIHRMSIQKAKPVLVETEHKDRTLFVNQNFAKAEQDAQGDENSPNCDHPAANNVMGSTSNSTRPRYSSDRQLTEKETSGSMCPQPESVEQIMDTEIKGGAATKDDSLEKKPKKMVVEADIEDIKKTQQRSLMDWSFTEHFQPKVLLQVLQEAHQQYRCVDSYYHTQDNSLLLVFHNPMNLHHLHCEYWNIALHSNVGFRNYLELVAKSIEEWVIQEEAKYQEAKMAEELNRAKNELDLKATTAKTSASKIGGPKKSKSNKVSSKTELTDQEKDKEKEKEKEKDKIPFILEGSLKAWKEEQERLAEEERLKEEKKAEKKGKEAGRKKGKDKADKEDTKSLKKKSSSKEKPKEEPSKSLEAIEEAVPLPEPEIVYPFRGYNMGDIPIQISGTNYYLYPSDGGQIEVEKIRFERGPTFIKVKVKKDKHSFIIHLKDPKEIVKREKEEEHSEEEEEEEEEEEEEEEEENEQKEGKEENVKQNVEMKRTQIKKEAVSKFGSFSATLENGICLSISYYGSNGMAPEVMDSDLEAMMNIPSAMTATVVPSIVTVPQGKGKTKPKGKEKHKDSFKEEELPKEEEKKNHSQEEVEPEIVIQETPYVPTFQNLNVSCPNGLLLTFIGQESTDEESTWNLMIRQSYPQRLKHYEFYKAVMPPTEQEASRVVTSQGTVIKYMLDGSTQILFADGAVSSSPDSGPVHASPETSASPHNGDVADNTSQHKSETAPSEIITKKGKGHKNQTSTASKSEAHDTLPEVVPTPMESHTGTWFTTTPDGRRIGTKGLEKITNLKPFLFFQATDPINGTVMTTREDKVIIVEKKDGTRIVDHADGTRITTFYQVYEDHITPPNDEETTEDPRTVTRQVKCMRIESSHYATIITNCEDSSCCATFGDGTSIIAKPQGSYQVLPSNTGCLYIDKDCSATYCHELSSNMYHPFQKREELRASRYIMKHTSEVICEVQDPEGNIFKVMADGSVSTALPKKKLEDKLNVQTEGYESLSSLHLEKNRMQIYGEHVPRFFVVYTDGSGVELLRDSDIEEYLSLAYGESTTVVLQEPVQEHPGALSITVLRPFHEASQWIMKKELDSIVPPNLQSRSWETFPSVEKKTPGPPFGTQIWKGLCIGAKQLTNIPAPILEGPKVLQMRQFIQHEVIKNEVKLKLQISLKDYINHILKKEDEQQEMTVKDSRTEEERGNAADLLKLVMSFPKMEETTKSHVTEVAAHLTDLFKQSMASAPKCSPENFTKDFFEKKWREAPQGKSWKEKLEQQRNNIKKTQNYLMQIRTKEVTPYFKSELSPLIKSQYDYLEKLSKNLPPFTKKNEAETKTADPDLHSDSTLTVDAKKEVSDAHPLPNQEVAENSQESTGQKETEYVTKYLQTSSPPNQYEHLTKSPKESYSQSQSEIETNATKEPAGQNHTEKFKISTKKSASQNQIENLIKSTKEPAGQSQMENISRPPTEEPENFMPIKIPTQSLLQDVTGKARKEKVRLPHYMMSCKPKCQPHTKVEDSVGGKVNTSSIACAAIYNPDVSPFGFHLLPPSIQFGVLKEGHTYATIVKLKNVGVDFCRFRVKQPPPSTGLKVTYKPGPVAAGLQAELKVELFAMAVGEDGAKDSAHISHTIEILTEHDVLFLPVEATVLTSSNYDNRPKDLPQGRENPMVYRTSTISSSALGVVMSQKATRH", "length": 2254 }, "evidence": [ { "id": "A0A8V0ZU97", "url": "https://omabrowser.org/oma/group/A0A8V0ZU97/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1BA36-1", "protein_name": "Sperm associated antigen 17", "gene_name": "SPAG17", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAPKKEKGGTTTTGSKIWEPSLIAAQFNQNDWKGSIAFVLGNRIEDEVLIRALTLAVQVPQRRLFSIVSWQDIVQQVNGSSALFGSTSKKAKKPVGGNNAPLYYEVLTAAKAIMDSGEKLTLPLIGKLLKFQLLQIKLKDQQRRESEKKVIEDRFKIEKDKVKAKSPKEKKSPSAKVAKGKGKDQPEANIAVKKTTQLVRRGEEDDTKQYIDDEPDDGAQHYFIVVGFNNPQLLAIMTELGIPISSVIKISSENYEPLQTHLAAVSQQQESFLQPEEIEAEKLKKENGIKELEIFWKYLEPILNNQKPETNLFDVAQLEYTVKADKFPSDWSDSEMLLGLGTDIFENVACLMYDTLDWKRQHQHYLESMRLINVPQVVSEKPIFEVTLIPEPPPPVVAVPGKKKTQAYEEPQIPAPPPATLLPPLPVASVITNEVDMRYYNDLLNPIPEEFISVPLILHCMLEQVVASEEDLVPPSLVEPPPRADGLDYRIAAHIVSILPSLCLTEREKKNLHEIFLSEEENESKPVPTGPLLLNYHDAHAHKKYMLKDLKNFDPVQIEQEMQSKLPLWEFLKFPLPPPWNSTKRLATIHELMHFCTSEVLSWNEVERAFKVFTFESLKLSEVDEDGNLKRSKMMYGTDSEMFNIPWDNPARFAKQIRQQYIMKMNTQEAKQQTDDGAKDRILFLNQNWSTPMPDDALNKEPSDCRQPGSNKKSLDSDNREPTEQERNLKSQLQPETLEQTMNNEIKDEAVTNADLLEKKPKKMTVEAELEDIKKTQQRNLMDWSFTEHFKPKVLLQVLQEANQQYRCIDSYYHTQDNSLLLVFHNPMNLQRLRHEYWKVGLHSNVGFRNYLELVAKSIQDWIIKEEAIYQETKMSDEINKAKYELEIKSSVATKVSSTSKIYSIKKSKSNKGMSKTEISDQEKDKEKEKEKINFILEGSLKAWKEEQDRLAEEERLKEEKKAEKKSKEAVKKKGKEKVEKEDSKIFKKKSFIKEKLKEEQMKIPEVTEEPLQEPEPERVYPFHGYNMGEIPVQISGTNYYLYPSDGGQIEVEKTTFEKGPTFIKVKVKKDKHNFLIHLRDPRKIVEKEEKEGDYLSEDEKEEREREQNFEAEGSNAENKAVSKFGSFSATLENGICLSISYYGSSGSAPEDKDPNLESMLNIPSVHTPTVIPVIVSIPQGKGKGKTKGKEKPKESLKEEEHPKEEEKKEAEEPEPVLQESPRAPIFQNLNVSCPNGLQVTFTGQESPDQCIVDEEPTWDIMVRQTYPQKVKHYEFYKTVMPPLGQEVSRVITSQGTVVKYMLDGSTQILFADGTVSSSPNSGPVSLPTDMPASAHSADLMDTISQQKSETAPSETVITKKGKIQKNQSPMAHKNESHEPPPETVQTITPMDVHLGTWFTTTPQGNRIGTKGSERIADLAPFLFFKATDPVNGTVMTTREDKVIIIEKKDGTRIVDHADGTRITTFYQVYEDPTISSEDQETAEGPQRIARQVKCMRVESSHYATVITNCEDSSCCATFGDGTSIIAKPQGTYQVLPPNTGCLHIDRDCSAIYCHESSSDIYHPFQKREQLRASRYIMKHTSEVICEVMDPEGNTFQVMADGSASTILPENNLEDDLNAKAEGYDSLSSTHLHKNHLQIYGEHVPRFFVIYADGSGVELLRDSDIEEYLSLAYGESTTVVLQEPVQEQPGALSITVLRPFHEVSPWLVKKELDTIVPPNLQSRTWETFPSVQKKTPGPPFGTQIWKGLDIGSKQLVNTPAPILKSPSVLQTRQFIQHEVIKNEVKLKLQISLKDYINHILKKEDELQEMTVKDSRTEEERGNAADLLKLVMSFPKMEETTKSHVTEVAAHLTDLFKQSLANATECPPETFETDFLEKKLRHTETTKRWKEKLAQKRKEIEKTQNYLKEIRSKVISPYFKSELSKLYQSQFNYLDTLSKNLPPLTKKDEDASKEAAQDTSSPPPDSQKNKVSKQESSDILSVSKSENLEDTKEPASQKQTENLTVSIKEPESCMPLKIPTQSLLQDVAGQARKEKVRLPHYLLSSKPKSQPLAKAQDSVGGRVRTSSVASAAINNINSSPFGFHLLPPVVKFGVLEEGHTYATTVKLKNVGVDFCRFRVKQPPPSTGLKVTYTPGPVAAGLQADLKVELFAMAVGEDGTKGLAHISHNIEIMTEHDVLFLPVEATVLTSSNYDKRPKDFPQGKENPMVQRISTISSSALGVFMSRKISPH", "length": 2229 }, "evidence": [ { "id": "A0A8V0ZU97", "url": "https://omabrowser.org/oma/group/A0A8V0ZU97/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q5S003-1", "protein_name": "Sperm-associated antigen 17", "gene_name": "Spag17", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAPKKEKPTGSANYKIWEPSLIAAHLNQNDWKASIAFVVGNRVEDDLLIHALDLAVRLPQRKLFSIVSWEDILQQMDEIQSLAESASAKKGKKPTSVNLPLHYEVFLAAKIIMESGEKLTLPLIGKLLKCQLLHIKSKDQQRRENEKKMVEERTKSEKDKGKGKSPKEKKVASAKPGKGKSKDQPEATVTVRKTTQLKRRGEDDEAKSYIDDEPDDGAQYYIIVVGFNNPQLLAIMTELGIPITSVIKISSENYEPLQTHLAAVRQQQEAVLQPEDIEAEKLKRKNSIKELEVFWKYLEPILNNEKLEIHLFDVARLQYMVKATYFPSDWSDNEQMLALGTEIFENIACLMYDSLDWKRQHHHYLQSMQLINVPQVVSEKTVLEAITIPEPPPSTAPAPTGKKKAQYEESHAPPTVAFIITTEVDMRYYNDLLNPIPEEFISVSLILHCMVEQVVATEEDLIPPSLVEPAPRADGLDYRIAAHIVSILPSLCLSEKEKKNLREIFLTEGESESKALPKGPLLLNYHDAHAHKKYALKDQKNFDPVQVEQEMQSKLPLWEFLQFPLPPPWNSTKRLATIHELMHFCTNEVLSWNEVERAFKVFTFESLKLSEVDEEGRLKPTETTSDTDVENFNIPWDNPARFAKLIRQRYIHRMSMQKAPPVVVEIENTERTLFVNKNFAKAEQDAQGDENSPNSDEPDAISVTGSTSNSTKPWNSSNRQFSEKETSGSMWPQPESMDQTMDTEIKDDAATKDDSPEKKPKKMVVEADIEDIKKTQQRSLMDWSFTEYFQPKVLLQVLQEAHQQYRCVDSYYHTQDNSLLLVFHNPMNLQRLQCEHWNIALHSNVGFRNYLELVAKSIEDWVTQEEAKYQEAKMAEELNRIRIELELKATVKTSASKIPGPKRSKTNKVSSKTELSDQEKDKEKEKDKIPFVLEGSLKAWKEEQERLAEEERLKEEKKAEKKGKDTGKKKGKDKADKDDAKALKKKSSSKEKPKEEPAKTLEVIEETAPLPVPEVVYPFRGYNMGDIPIQISGTNYYLYPSDGGQIEVEKTRFERGSTFIKVKVKKDKHNFIIHLKDPKEIVKKEKEEKNSEEEEEEEEEKEEVEEKKPKEGEEEKVKQKVEMKRAQIEKEAVSKFGSFSATLENGICLSISYYGSNGMAPEVINSELEAMMNIPSAMTATVVPAVVTVPQGKGKAKPKGKEKHKDSIKEEELPKEEEKKNHIQEEVEPEIVIQESPPYVPTFQNLNVSCPSGLLLTFIGQESTDYSIVDEEPTRNLMIRQSYPQRLKHYEFYKAVMPPLEQEASRVVTSQGTVIKYMLDGSTQILFADGAVSSSPDSGPVYTSPELPTSPHNGDLVDSASQPKSETGPEIIITKKGKGHKNQTVANKSETHDIIPEVPPPTPVESHIGTWFTTTPDGRRIGTKGLEKIEDLKPYLFFQATDPINGTVMTTREDKVIIVEKKDGTRVVDHADGTRITTFYQVYEDHITPSNDEETTEGPRTVTRQVKCMRIESSHYATIITNCEDSSCCATFGDGTSIIAKPQGSYQVLPPNTGCLYIDKDCSATYCHESSNNLYHPFQKREQLRASRYIMKHTSEVICEVQDPEGNTFQVMADGSVSTTLPKKKLEDDFNVQMEGYESLSSLHLEKNHMQIYGEHVPRFFVVYTDGSGVELLRDSDIEEYLSLAYGESTTVVLQEPVQEYPGALSITVLRPFHEASQWIMKKELDTIVPPNLQSRSWERFPSVEKKTPGPPFGTQIWKGLSIGSKQLTNIPAPILEGPKVLQMRQFIQHEVIKNEVKLKLQISLKDYINHILKKEDELQEMTVKDSRTEEERGNAADLLKLVMSFPKMEETTKSHMTKVAAHLTVLFKQSMASAPKCSPDSYSKEFLEKKWRSLSQGTSWKEKLEQQRNNIKKTQSYLMQIKTKEVTPYFKSELSSLFKSKYDYLEKFSKSLPPFVKKNEAKLMTAVPDLYSDSTLTVDTEKEASNTHPLLNQEVAENIQESPREKETEYVNKSLQTSSSQNQYENVTISPKESVYQSQTEIETKDTKESAIQNFTEKFKKYTKKSASQNEIEDLIKSTKESVSQRQTENVTRPPTEEPDIYMPIKIPTQSLLQDVTGQARKEKVRLPYYMMSSKPKSQPYAKVEDPVGGRVNTSSIASAAMYNPNASPFGFHLLPPSVKFGVLKEGHTYATIVKLKNVGVDFCRFRVKQPPPSTGLKVTYKPGPVAAGLQAELKVELFAMAVGEDGAKGSAHISHNIEIMTEHDVLFLPVEATVLTSSNYDNRPKNLPQGKENPMVFRTSTISSSSLGVVMSQKATHH", "length": 2320 }, "evidence": [ { "id": "A0A8V0ZU97", "url": "https://omabrowser.org/oma/group/A0A8V0ZU97/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6Q759-1", "protein_name": "Sperm-associated antigen 17", "gene_name": "SPAG17", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAPKKEKGGTVNTSSKIWEPSLIAAQFNQNDWQASIAFVVGNQIEDDLLIQALTVAVQVPQRKLFSMVSWQDILQQINEINTLVGSASSKKAKKPVGGNAPLYYEVLTAAKAIMDSGEKLTLPLIGKLLKFQLLQIKFKDQQRRENEKKVIEDKPKLEKDKGKAKSPKEKKAPSAKPAKGKGKDQPEANAPVKKTTQLKRRGEDDHTNRYIDDEPDDGAQHYIIVVGFNNPQLLAIMAELGIPITSVIKISSENYEPLQTHLAAVNQQQEVLLQSEDLEAEKLKKENAIKELKTFWKYLEPVLNNEKPETNLFDVARLEYMVKAADFPSDWSDGEMMLKLGTDIFENIACLMYDILDWKRQHQHYLESMQLINVPQVVNEKPVLEAMPTSEAPQPAVPAPGKKKAQYEEPQAPPPVTSVITTEVDMRYYNYLLNPIREEFISVPLILHCMLEQVVATEEDLVPPSLREPSPRADGLDHRIAAHIVSLLPSLCLSEREKKNLHDIFLSEEENESKAVPKGPLLLNYHDAHAHKKYALQDQKNFDPVQIEQEMQSKLPLWEFLQFPLPPPWNNTKRLATIHELMHFCTSDVLSWNEVERAFKVFTFESLKLSEVDEKGKLKPSGMMCGSDSEMFNIPWDNPARFAKQIRQQYVMKMNTQEAKQKADIKIKDRTLFVDQNLSMSVQDNESNREPSDPSQCDANNMKHSDLNNLKLSVPDNRQLLEQESIMKAQPQHESLEQTTNNEIKDDAVTKADSHEKKPKKMMVEADLEDIKKTQQRSLMDWSFTEHFKPKVLLQVLQEAHKQYRCVDSYYHTQDNSLLLVFHNPMNRQRLHCEYWNIALHSNVGFRNYLELVAKSIQDWITKEEAIYQESKMNEKIIRTRAELELKSSANAKLTSASKIFSIKESKSNKGISKTEISDQEKEKEKEKIPFILEGSLKAWKEEQHRLAEEERLREEKKAEKKGKEAGKKKGKDNAEKEDSRSLKKKSPYKEKSKEEQVKIQEVTEESPHQPEPKITYPFHGYNMGNIPTQISGSNYYLYPSDGGQIEVEKTMFEKGPTFIKVRVVKDNHNFMIHLNDPKEIVKKEEKGDYYLEEEEEGDEEQSLETEVSDAKNKAFSKFGSFSATLENGICLSISYYGSNGMAPEDKDPDLETILNIPSALTPTVVPVIVTVPQSKAKGKIKGKEKPKESLKEEEHPKEEEKKEEEVEPEPVLQETLDVPTFQSLNVSCPSGLLLTFIGQESTGQYVIDEEPTWDIMVRQSYPQRVKHYEFYKTVMPPAEQEASRVITSQGTVVKYMLDGSTQILFADGAVSRSPNSGLICPPSEMPATPHSGDLMDSISQQKSETIPSEITNTKKGKSHKSQSSMAHKGEIHDPPPEAVQTVTPVEVHIGTWFTTTPEGNRIGTKGLERIADLTPLLSFQATDPVNGTVMTTREDKVVIVERKDGTRIVDHADGTRITTFYQVYEDQIILPDDQETTEGPRTVTRQVKCMRVESSRYATVIANCEDSSCCATFGDGTTIIAKPQGTYQVLPPNTGSLYIDKDCSAVYCHESSSNIYYPFQKREQLRAGRYIMRHTSEVICEVLDPEGNTFQVMADGSISTILPEKKLEDDLNEKTEGYDSLSSMHLEKNHQQIYGEHVPRFFVMYADGSGMELLRDSDIEEYLSLAYKESNTVVLQEPVQEQPGTLTITVLRPFHEASPWQVKKEDTIVPPNLRSRSWETFPSVEKKTPGPPFGTQIWKGLCIESKQLVSAPGAILKSPSVLQMRQFIQHEVIKNEVKLRLQVSLKDYINYILKKEDELQEMMVKDSRTEEERGNAADLLKLVMSFPKMEETTKSHVTEVAAHLTDLFKQSLATPPKCPPDTFGKDFFEKTWRHTASSKRWKEKIDKTRKEIETTQNYLMDIKNRIIPPFFKSELNQLYQSQYNHLDSLSKKLPSFTKKNEDANETAVQDTSDLNLDFKPHKVSEQKSSSVPSLPKPEISADKKDFTAQNQTENLTKSPEEAESYEPVKIPTQSLLQDVAGQTRKEKVKLPHYLLSSKPKSQPLAKVQDSVGGKVNTSSVASAAINNAKSSLFGFHLLPSSVKFGVLKEGHTYATVVKLKNVGVDFCRFKVKQPPPSTGLKVTYKPGPVAAGMQTELNIELFATAVGEDGAKGSAHISHNIEIMTEHEVLFLPVEATVLTSSNYDKRPKDFPQGKENPMVQRTSTIYSSTLGVFMSRKVSPH", "length": 2223 }, "evidence": [ { "id": "A0A8V0ZU97", "url": "https://omabrowser.org/oma/group/A0A8V0ZU97/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "axonemal central apparatus assembly", "id": "GO:1904158", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904158", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZU97", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU97" } ], "pmid": "" }, { "name": "epithelial cilium movement involved in extracellular fluid movement", "id": "GO:0003351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZU97", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU97" } ], "pmid": "" }, { "name": "motile cilium assembly", "id": "GO:0044458", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044458", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZU97", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU97" } ], "pmid": "" }, { "name": "manchette assembly", "id": "GO:1905198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905198", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZU97", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU97" } ], "pmid": "" }, { "name": "intramanchette transport", "id": "GO:1990953", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990953", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZU97", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU97" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "axonemal central apparatus", "id": "GO:1990716", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990716", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZU97", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU97" } ], "pmid": "" }, { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { 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"https://www.uniprot.org/uniprotkb/A0A8V0ZU99/entry#names_and_taxonomy" } ] }, { "name": "secernin-2", "type": "synonym", "evidence": [ { "id": "XP_015154970", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015154970" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052558.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015154970.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015154970", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015154970" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZU99", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU99" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SCRN2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU99", "locus": { "chromosome": "27", "start_pos": 3725675, "end_pos": 3723087, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010023770", "url": "https://www.ensembl.org/id/ENSGALG00010023770" } ] } } ], "crossref": [ { "id": "A0A8V0ZU99", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZU99", "database": "AlphaFoldDB", "categories": [] }, { "id": "425759", "url": "https://www.ncbi.nlm.nih.gov/gene/425759", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR005322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:425759", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:425759", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QAQGWWG", "url": "https://omabrowser.org/oma/group/QAQGWWG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZU99", "url": "https://www.orthodb.org/?gene=A0A8V0ZU99", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12994", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12994", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12994:SF16", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12994:SF16", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03577", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03577", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015154970", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015154970", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZU99", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU99", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZU99-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU99-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAGHDPAPSCCDCFVALPPHTAAPAVVFGKNADRPRHEVQEIAYIPSAVHRPGDKVQCTYIEIEQAERTHAVVLSRPAWLWGAEMGANEHGVCVGNEGVWTREPVGEGEALLGMDLVRLGLERGGSAREALEVITALLEQHGQGGSCKEEPIPFVYHNTFLLADRHEAWVLETAGRYWAAQQIREGSRNISNQLSIGTDITAEHPGLRQRAQSQGWWSGVGQFSFAEVFSLAQQPPRMEAAKSRYRAGKELLQQHAGRITAETFMAILRDKDSGICVDSEGFRTAGSMVSVLPQDPALPCVHFFTATPDPSRSVFKPFVFVPGLKPAPQVSSPTFSDDPAKKVPRFQSTVDRRHELYCRHQAALELMEKDQERGQELLQTLRDLEKQGLEAVNALLAGNVAPKPEELAELFFDCVDAEMKFYK", "length": 423, "header": "tr|A0A8V0ZU99-1|A0A8V0ZU99_CHICK Isoform 1 of Secernin-2 OS=Gallus gallus OX=9031 GN=SCRN2 PE=1 SV=1 CANONICAL=A0A8V0ZU99-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZU99-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU99/entry#A0A8V0ZU99-1", "sequence": { "sequence": 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"keywords": [], "publication": [], "pathway": [ { "id": "gga:425759", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:425759", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287BJ40-1", "protein_name": "Secernin-2", "gene_name": "SCRN2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MASWSPDTPCSCDCFVSVPPASAIPAVIFAKNSDRPRDEVQEVVFVPAGTHAPGSRLQCTYIEVEQVPKTHAVILSRPSWLWGAEMGANEHGVCIGNEAVWTKEPVGEGEALLGMDLLRLALERGSSAQEALHVITGLLERYGQGGSCREDPTPFCYHNTFLLADRTEAWVLETAGRLWAAQRIQAGARNISNQLSIGTDLSAEHPKLRPHARAQGWWDGQGAFDFAQAFSLTQQPVRMEAAKARFQAGRLLLQQKQGAITAEVMMGILRDKASGICMDSGGFRTTASMVSLLPRDPTQPCVHFLTATPDPARSVFKPFIFGVGAAQAPLVLSPTFGAQDPVQTLPRFQTRVDRRHTLYCRHQVALGLMESEQDRGQQLRQKQQDLEQEGLEAVRGLLAGEWAPRPQELGGLFQAFVEKESQAYA", "length": 425 }, "evidence": [ { "id": "A0A8V0ZU99", "url": "https://omabrowser.org/oma/group/A0A8V0ZU99/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q5TYS5-1", "protein_name": "Secernin-2", "gene_name": "scrn2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAEPPRSCDCFVSLPPGSKEDYVIFGKNSDRPRDEVQEVVYFPASSHPPASTVECTYISIPQVEHTNAVVLSRPAWLWGAEMGANEHGVCVGNEAVWTKEPVNPEEALLGMDLVRLGLERGDSARAALNVITALLEQFGQGGACRETSEPFSYHNTFLLVDRQEAWVLETAGKLWAAQKVTEGVKNISNQLTIDFEISAEHPDLRSVAQAQGWWSGEGDFSFTAVFSPDHPPARMEMAKQRYRGGTALLQQHNGSVTAEVMMSILRDKASGICMDSEGFRTTGSMVSILPRNPNMPCVHFLTATPDPSRSVFKPFIFSESVRPVSMVMSPQYGPGDPVRTLPRFQHQVDRKHELYKAHQMANTSSDAGVSLQDTMRYLESQCLEEIEAMLRGEVQGQELGDLFFDCVDAEIKFYQ", "length": 415 }, "evidence": [ { "id": "A0A8V0ZU99", "url": "https://omabrowser.org/oma/group/A0A8V0ZU99/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q6AYR8-1", "protein_name": "Secernin-2", "gene_name": "Scrn2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASSSPDAPCSCDCFVSVPPASAIPAVIFAKNSDRPRDEVQEVVFIPAGTHTPGSRLQCTYIEVEQVWKTHAVILSRPSWLWGAEMGANELGVCIGNEAVWTKEPVGEGEALLGMDLLRLALERSSTAQAAVHVIAGLLDRYGQGGSCREDPEPFCYHNTFLLADRTEAWVLETAGRLWAAQRIQGGARNISNQLSIGTDISAEHPELRSHAKAQGWWSGQGVFDFAEVFSLTQQPVRMEAAKARFRAGCEMLQRQQGSITAEVMMDILRNKESGICMDSGGFRTTASMVSVLPQDPTKPCVHFLTATPDPSRSVFKPFIFEVGVSQPPQVLSPTFGAQDPVRILPRFQTQVDRRHSLYRGHQAALGLMDEQEQAQLRQEQQSLEQEGLEALRGLLTGEQTPAPQELGSLFQAFVEREHQVYA", "length": 423 }, "evidence": [ { "id": "A0A8V0ZU99", "url": "https://omabrowser.org/oma/group/A0A8V0ZU99/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8VCA8-1", "protein_name": "Secernin-2", "gene_name": "Scrn2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASSSPDAPCSCDCFVSVPPASAIPAVIFAKNSDRPRDEVQEVVFIPAGTHVPGSRLQCTYIEVEQVGKTHAVILSRPSWLWGAEMGANELGVCIGNEAVWTKEPVGQGEALLGMDLLRLALERSSTAQEAVHVIAGLLDRYGQGGSCREDPEPFCYHNTFLLADRTEAWVLETAGSLWAAQRIQGGARNISNQLSIGTDISAEHPELRSHAKAQGWWTGQGLFDFAEVFSLTQQPVRMEAAKARFRAGCEMLQRHQGNITAEVMMGILRDKESGICMDSGGFRTTASMVSVLPQDPTKPCVHFLTATPDPSRSVFKPFIFEVGVSQSPQVLSPTFGAQDPVRILPRFQTRVDRRHSLYRGHQAALGLMEDEQEQAQQLRKKQQRLEQEGLEALRGLLTGEQTPPAQGLGSLFQAFVEREEQAYA", "length": 425 }, "evidence": [ { "id": "A0A8V0ZU99", "url": "https://omabrowser.org/oma/group/A0A8V0ZU99/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96FV2-1", "protein_name": "Secernin-2", "gene_name": "SCRN2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASSSPDSPCSCDCFVSVPPASAIPAVIFAKNSDRPRDEVQEVVFVPAGTHTPGSRLQCTYIEVEQVSKTHAVILSRPSWLWGAEMGANEHGVCIGNEAVWTKEPVGEGEALLGMDLLRLALERSSSAQEALHVITGLLEHYGQGGNCLEDAAPFSYHSTFLLADRTEAWVLETAGRLWAAQRIQEGARNISNQLSIGTDISAQHPELRTHAQAKGWWDGQGAFDFAQIFSLTQQPVRMEAAKARFQAGRELLRQRQGGITAEVMMGILRDKESGICMDSGGFRTTASMVSVLPQDPTQPCVHFLTATPDPSRSVFKPFIFGMGVAQAPQVLSPTFGAQDPVRTLPRFQTQVDRRHTLYRGHQAALGLMERDQDRGQQLQQKQQDLEQEGLEATQGLLAGEWAPPLWELGSLFQAFVKRESQAYA", "length": 425 }, "evidence": [ { "id": "A0A8V0ZU99", "url": "https://omabrowser.org/oma/group/A0A8V0ZU99/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZU99", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU99" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZU99", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU99" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "dipeptidase activity", "id": "GO:0016805", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016805", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZU99", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU99" } ], "pmid": "" }, { "name": "cysteine-type exopeptidase activity", "id": "GO:0070004", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070004", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZU99", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU99" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 189, "end_pos": 191, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 189, "end_pos": 191 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZUA2-1", "uniprot_ac": "A0A8V0ZUA2", "uniprot_id": "A0A8V0ZUA2_CHICK", "mass": { "chemical_mass": 60126.0, "monoisotopic_mass": 60126.0 }, "refseq": {}, "gene_names": [ { "name": "VCAM1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZUA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUA2" } ] } ], "protein_names": [ { "name": "Vascular cell adhesion molecule 1", "type": "synonym", "evidence": [ { "id": "A0A8V0ZUA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUA2/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZUA2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUA2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "VCAM1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUA2", "locus": {} } ], "crossref": [ { "id": "A0A8V0ZUA2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZUA2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000005257", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000005257", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00096", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00096", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "424467", "url": "https://www.ncbi.nlm.nih.gov/gene/424467", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003987", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003987", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008424", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008424", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013098", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013098", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013151", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013151", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047012", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047012", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "TYVCEGV", "url": "https://omabrowser.org/oma/group/TYVCEGV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZP21", "url": "https://www.orthodb.org/?gene=A0A8V0ZP21", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZP25", "url": "https://www.orthodb.org/?gene=A0A8V0ZP25", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZUA2", "url": "https://www.orthodb.org/?gene=A0A8V0ZUA2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZWB3", "url": "https://www.orthodb.org/?gene=A0A8V0ZWB3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A1S5", "url": "https://www.orthodb.org/?gene=A0A8V1A1S5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1P201", "url": "https://www.orthodb.org/?gene=F1P201", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13771", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13771", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13771:SF14", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13771:SF14", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00047", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00047", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF05790", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05790", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07679", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07679", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13927", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13927", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZP21", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP21", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZP21-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP21-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZP25", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP25", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZP25-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP25-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZUA2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUA2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZUA2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUA2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZWB3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWB3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZWB3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWB3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A1S5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1S5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A1S5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1S5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1P201", "url": "https://www.uniprot.org/uniprotkb/F1P201", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1P201-1", "url": "https://www.uniprot.org/uniprotkb/F1P201-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPSEQYPKTEIQPFVKNLAEAACEVKAFEMEITPADRVVERIGATLILTCNTTGCALPKFSWRTQMDYPLGGKVYNNKTHSTLTMNPVSAENYNDYLCTVICNKEKKEKSVKVELYSFPSDPIIETSASLVVGETATVICKIHDVFPSDHLELLLKKDEQILHRKTFEGDVSTKTETKTVAYSFNLTTEDNGKEIVCVARLQIAGMDFEPKERLTSLKLNANFGPQNTSINASPGNSLMEGHFLKLTCMTDSNPPAQVFWRKHLAKETIQHFIENSVLSIPHAHFTDSGQYICEVVNPVTNKTEKATTNIVIQAPPKNASLMVFPSSSVKEGESVTISCSATGVPAVQIILEKKIGDVVTTLKTEDGKYTIDKVQPEDAGKYECTFTNKFGNHSLDVELDVKVPPQNITVLVYPSENVKEGENVTIMCSTYSNPPSQMILKKVNQDEEIILPAVNGTFTLYNVTKNDTGRYLLDVFNEVGNNIKVIEIAVVGKLEKPDQIMPLMIALSCVTAIAIPVVAILIYVSRKAKINGSYSLVKALRLKV", "length": 544, "header": "tr|A0A8V0ZUA2-1|A0A8V0ZUA2_CHICK Isoform 1 of Vascular cell adhesion molecule 1 OS=Gallus gallus OX=9031 GN=VCAM1 PE=1 SV=1 CANONICAL=A0A8V0ZUA2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZP21-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUA2/entry#A0A8V0ZP21-1", "sequence": { "sequence": "MRRQIFCSVKAFEMEITPADRVVERIGATLILTCNTTGCALPKFSWRTQMDYPLGGKVYNNKTHSTLTMNPVSAENYNDYLCTVICNKEKKEKSVKVELYSFPSDPIIETSASLVVGETATVICKIHDVFPSDHLELLLKKDEQILHRKTFEGDVSTKTETKTVAYSFNLTTEDNGKEIVCVARLQIAGMDFEPKERLTSLKLNANFGPQNTSINASPGNSLMEGHFLKLTCMTDSNPPAQVFWRKHLAKETIQHFIENSVLSIPHAHFTDSGQYICEVVNPVTNKTEKATTNIVIQAPPKNASLMVFPSSSVKEGESVTISCSATGVPAVQIILEKKIGDVVTTLKTEDGKYTIDKVQPEDAGKYECTFTNKFGNHSLDVELDVKVPPQNITVLVYPSENVKEGENVTIMCSTYSNPPSQMILKKVNQDEEIILPAVNGTFTLYNVTKNDTGRYLLDVFNEVGNNIKVIEIAVVGKLEKPDQIMPLMIALSCVTAIAIPVVAILIYVSRKAKINGSYSLVKALRLKV", "length": 528, "header": "tr|A0A8V0ZP21-1|A0A8V0ZP21_CHICK Computationally mapped isoform of Vascular cell adhesion molecule 1 OS=Gallus gallus OX=9031 GN=VCAM1 PE=1 SV=1 CANONICAL=A0A8V0ZUA2-1" }, "locus": { "chromosome": "8", "start_pos": 11613044, "end_pos": 11591581, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010057957.1", "url": "https://www.ensembl.org/id/ENSGALT00010057957.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035155.1", "url": "https://www.ensembl.org/id/ENSGALP00010035155.1" } ] } }, { "isoform_ac": "A0A8V0ZP25-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUA2/entry#A0A8V0ZP25-1", "sequence": { "sequence": "MTVKAFEMEITPADRVVERIGATLILTCNTTGCALPKFSWRTQMDYPLGGKVYNNKTHSTLTMNPVSAENYNDYLCTVICNKEKKEKSVKVELYSFPSDPIIETSASLVVGETATVICKIHDVFPSDHLELLLKKDEQILHRKTFEGDVSTKTETKTVAYSFNLTTEDNGKEIVCVARLQIAGMDFEPKERLTSLKLNANFGPQNTSINASPGNSLMEGHFLKLTCMTDSNPPAQVFWRKHLAKETIQHFIENSVLSIPHAHFTDSGQYICEVVNPVTNKTEKATTNIVIQAPPKNASLMVFPSSSVKEGESVTISCSATGVPAVQIILEKKIGDVVTTLKTEDGKYTIDKVQPEDAGKYECTFTNKFGNHSLDVELDVKVPPQNITVLVYPSENVKEGENVTIMCSTYSNPPSQMILKKVNQDEEIILPAVNGTFTLYNVTKNDTGRYLLDVFNEVGNNIKVIEIAVVGKLEKPDQIMPLMIALSCVTAIAIPVVAILIYVSRKAKINGSYSLVKALRLKV", "length": 522, "header": "tr|A0A8V0ZP25-1|A0A8V0ZP25_CHICK Computationally mapped isoform of Vascular cell adhesion molecule 1 OS=Gallus gallus OX=9031 GN=VCAM1 PE=1 SV=1 CANONICAL=A0A8V0ZUA2-1" }, "locus": { "chromosome": "8", "start_pos": 11613044, "end_pos": 11572404, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010057966.1", "url": "https://www.ensembl.org/id/ENSGALT00010057966.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035160.1", "url": "https://www.ensembl.org/id/ENSGALP00010035160.1" } ] } }, { "isoform_ac": "A0A8V0ZUA2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUA2/entry#A0A8V0ZUA2-1", "sequence": { "sequence": "MPSEQYPKTEIQPFVKNLAEAACEVKAFEMEITPADRVVERIGATLILTCNTTGCALPKFSWRTQMDYPLGGKVYNNKTHSTLTMNPVSAENYNDYLCTVICNKEKKEKSVKVELYSFPSDPIIETSASLVVGETATVICKIHDVFPSDHLELLLKKDEQILHRKTFEGDVSTKTETKTVAYSFNLTTEDNGKEIVCVARLQIAGMDFEPKERLTSLKLNANFGPQNTSINASPGNSLMEGHFLKLTCMTDSNPPAQVFWRKHLAKETIQHFIENSVLSIPHAHFTDSGQYICEVVNPVTNKTEKATTNIVIQAPPKNASLMVFPSSSVKEGESVTISCSATGVPAVQIILEKKIGDVVTTLKTEDGKYTIDKVQPEDAGKYECTFTNKFGNHSLDVELDVKVPPQNITVLVYPSENVKEGENVTIMCSTYSNPPSQMILKKVNQDEEIILPAVNGTFTLYNVTKNDTGRYLLDVFNEVGNNIKVIEIAVVGKLEKPDQIMPLMIALSCVTAIAIPVVAILIYVSRKAKINGSYSLVKALRLKV", "length": 544, "header": "tr|A0A8V0ZUA2-1|A0A8V0ZUA2_CHICK Isoform 1 of Vascular cell adhesion molecule 1 OS=Gallus gallus OX=9031 GN=VCAM1 PE=1 SV=1 CANONICAL=A0A8V0ZUA2-1" }, "locus": { "chromosome": "8", "start_pos": 11613044, "end_pos": 11575465, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010057959.1", "url": "https://www.ensembl.org/id/ENSGALT00010057959.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035157.1", "url": "https://www.ensembl.org/id/ENSGALP00010035157.1" } ] } }, { "isoform_ac": "A0A8V0ZWB3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUA2/entry#A0A8V0ZWB3-1", "sequence": { "sequence": "MEAQKFSNAYFKAFEMEITPADRVVERIGATLILTCNTTGCALPKFSWRTQMDYPLGGKVYNNKTHSTLTMNPVSAENYNDYLCTVICNKEKKEKSVKVELYSFPSDPIIETSASLVVGETATVICKIHDVFPSDHLELLLKKDEQILHRKTFEGDVSTKTETKTVAYSFNLTTEDNGKEIVCVARLQIAGMDFEPKERLTSLKLNANFGPQNTSINASPGNSLMEGHFLKLTCMTDSNPPAQVFWRKHLAKETIQHFIENSVLSIPHAHFTDSGQYICEVVNPVTNKTEKATTNIVIQAPPKNASLMVFPSSSVKEGESVTISCSATGVPAVQIILEKKIGDVVTTLKTEDGKYTIDKVQPEDAGKYECTFTNKFGNHSLDVELDVKVPPQNITVLVYPSENVKEGENVTIMCSTYSNPPSQMILKKVNQDEEIILPAVNGTFTLYNVTKNDTGRYLLDVFNEVGNNIKVIEIAVVGKLEKPDQIMPLMIALSCVTAIAIPVVAILIYVSRKAKINGSYSLVKALRLKV", "length": 530, "header": "tr|A0A8V0ZWB3-1|A0A8V0ZUA2_CHICK Computationally mapped isoform of Vascular cell adhesion molecule 1 OS=Gallus gallus OX=9031 GN=VCAM1 PE=1 SV=1 CANONICAL=A0A8V0ZUA2-1" }, "locus": { "chromosome": "8", "start_pos": 11613044, "end_pos": 11584521, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010057955.1", "url": "https://www.ensembl.org/id/ENSGALT00010057955.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035154.1", "url": "https://www.ensembl.org/id/ENSGALP00010035154.1" } ] } }, { "isoform_ac": "A0A8V1A1S5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUA2/entry#A0A8V1A1S5-1", "sequence": { "sequence": "MLRRVKAFEMEITPADRVVERIGATLILTCNTTGCALPKFSWRTQMDYPLGGKVYNNKTHSTLTMNPVSAENYNDYLCTVICNKEKKEKSVKVELYSFPSDPIIETSASLVVGETATVICKIHDVFPSDHLELLLKKDEQILHRKTFEGDVSTKTETKTVAYSFNLTTEDNGKEIVCVARLQIAGMDFEPKERLTSLKLNANFGPQNTSINASPGNSLMEGHFLKLTCMTDSNPPAQVFWRKHLAKETIQHFIENSVLSIPHAHFTDSGQYICEVVNPVTNKTEKATTNIVIQAPPKNASLMVFPSSSVKEGESVTISCSATGVPAVQIILEKKIGDVVTTLKTEDGKYTIDKVQPEDAGKYECTFTNKFGNHSLDVELDVKVPPQNITVLVYPSENVKEGENVTIMCSTYSNPPSQMILKKVNQDEEIILPAVNGTFTLYNVTKNDTGRYLLDVFNEVGNNIKVIEIAVVGKLEKPDQIMPLMIALSCVTAIAIPVVAILIYVSRKAKINGSYSLVKALRLKV", "length": 524, "header": "tr|A0A8V1A1S5-1|A0A8V0ZUA2_CHICK Computationally mapped isoform of Vascular cell adhesion molecule 1 OS=Gallus gallus OX=9031 GN=VCAM1 PE=1 SV=1 CANONICAL=A0A8V0ZUA2-1" }, "locus": { "chromosome": "8", "start_pos": 11613044, "end_pos": 11596533, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010057950.1", "url": "https://www.ensembl.org/id/ENSGALT00010057950.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035151.1", "url": "https://www.ensembl.org/id/ENSGALP00010035151.1" } ] } }, { "isoform_ac": "F1P201-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUA2/entry#F1P201-1", "sequence": { "sequence": "MFKQMGRTSQTVLIILYVLMDVKAFEMEITPADRVVERIGATLILTCNTTGCALPKFSWRTQMDYPLGGKVYNNKTHSTLTMNPVSAENYNDYLCTVICNKEKKEKSVKVELYSFPSDPIIETSASLVVGETATVICKIHDVFPSDHLELLLKKDEQILHRKTFEGDVSTKTETKTVAYSFNLTTEDNGKEIVCVARLQIAGMDFEPKERLTSLKLNANFGPQNTSINASPGNSLMEGHFLKLTCMTDSNPPAQVFWRKHLAKETIQHFIENSVLSIPHAHFTDSGQYICEVVNPVTNKTEKATTNIVIQAPPKNASLMVFPSSSVKEGESVTISCSATGVPAVQIILEKKIGDVVTTLKTEDGKYTIDKVQPEDAGKYECTFTNKFGNHSLDVELDVKVPPQNITVLVYPSENVKEGENVTIMCSTYSNPPSQMILKKVNQDEEIILPAVNGTFTLYNVTKNDTGRYLLDVFNEVGNNIKVIEIAVVGKLEKPDQIMPLMIALSCVTAIAIPVVAILIYVSRKAKINGSYSLVKALRLKV", "length": 541, "header": "tr|F1P201-1|A0A8V0ZUA2_CHICK Computationally mapped isoform of Vascular cell adhesion molecule 1 OS=Gallus gallus OX=9031 GN=VCAM1 PE=1 SV=2 CANONICAL=A0A8V0ZUA2-1" }, "locus": { "chromosome": "8", "start_pos": 11613044, "end_pos": 11606414, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010057943.1", "url": "https://www.ensembl.org/id/ENSGALT00010057943.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035148.1", "url": "https://www.ensembl.org/id/ENSGALP00010035148.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "F1S567-1", "protein_name": "Vascular cell adhesion molecule 1", "gene_name": "VCAM1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPRNIVVIFGASNILWMVFAVSQNVKVEIFPEDKMIAQIGDSASLTCSAPDCESSLSFSWRTQIDSPLNGKVKTNGTRSTLVMNPVSFENEHSYLCTVSCGNKGERGIQVEIYSFPKDPEIHWSSLPEVGKPVTVRCLVPDVYPVEKLEIELLKDNHSMVSQNFLELIDIKSKETKSLEFTFTPTEEDIGKAIVCQATLIIDGQPSVKTTPEKMQVYISPKDPVISVNPSTSLQEGDSVMMTCTSEGLPAPQISWSKKLDNGDQQLLSGNATLTLIAMRMEDSGIYVCEGVNPVGTNRKEVELTVQVAPRDTTISVNPSSTLEEGSSVNMTCSSDGFPAPKILWSKKLRDGNLEPLSENTTLTLTSTKMEDSGIYVCEGINQAGINRKEVELIIQAAPKDLQLTAFPSESVKEGDTVIISCTCGNVPPTLIILKKKAETGDTVLKSTDGAYTIHRARLADAGVYECESKNEIGLQLRSITLDVKGRESNKDYFSSELLVLYCASSLIIPAIGVIIYFARKANMRGSYSLVDAQKSKV", "length": 537 }, "evidence": [ { "id": "A0A8V0ZUA2", "url": "https://omabrowser.org/oma/group/A0A8V0ZUA2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P19320-1", "protein_name": "Vascular cell adhesion protein 1", "gene_name": "VCAM1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPGKMVVILGASNILWIMFAASQAFKIETTPESRYLAQIGDSVSLTCSTTGCESPFFSWRTQIDSPLNGKVTNEGTTSTLTMNPVSFGNEHSYLCTATCESRKLEKGIQVEIYSFPKDPEIHLSGPLEAGKPITVKCSVADVYPFDRLEIDLLKGDHLMKSQEFLEDADRKSLETKSLEVTFTPVIEDIGKVLVCRAKLHIDEMDSVPTVRQAVKELQVYISPKNTVISVNPSTKLQEGGSVTMTCSSEGLPAPEIFWSKKLDNGNLQHLSGNATLTLIAMRMEDSGIYVCEGVNLIGKNRKEVELIVQEKPFTVEISPGPRIAAQIGDSVMLTCSVMGCESPSFSWRTQIDSPLSGKVRSEGTNSTLTLSPVSFENEHSYLCTVTCGHKKLEKGIQVELYSFPRDPEIEMSGGLVNGSSVTVSCKVPSVYPLDRLEIELLKGETILENIEFLEDTDMKSLENKSLEMTFIPTIEDTGKALVCQAKLHIDDMEFEPKQRQSTQTLYVNVAPRDTTVLVSPSSILEEGSSVNMTCLSQGFPAPKILWSRQLPNGELQPLSENATLTLISTKMEDSGVYLCEGINQAGRSRKEVELIIQVTPKDIKLTAFPSESVKEGDTVIISCTCGNVPETWIILKKKAETGDTVLKSIDGAYTIRKAQLKDAGVYECESKNKVGSQLRSLTLDVQGRENNKDYFSPELLVLYFASSLIIPAIGMIIYFARKANMKGSYSLVEAQKSKV", "length": 739 }, "evidence": [ { "id": "A0A8V0ZUA2", "url": "https://omabrowser.org/oma/group/A0A8V0ZUA2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P29534-1", "protein_name": "Vascular cell adhesion protein 1", "gene_name": "Vcam1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPVKMVAIFGASTVLWILFAVSQAFKIEISPEYKTLAQIGDSMLLTCSTTGCESPSFSWRTQIDSPLNGKVKTEGAKSVLTMDPVSFENEHSYLCTATCNSGKLERGIQVDIYSFPKDPEIQFSGPLEVGKPVMVKCLAPDVYPIDRLEIELFKGDRLMKKQDFVDEMAKKSLETKSLEVIFTPVIEDIEKALVCRAKLYIDQTDSIPKERETVRELQVYTSPKNTEISVHPSTRLHEGAAVTMTCASEGLPAPEIFWSKKLDNGVLQLLSGNATLTLIAMRMEDSGIYVCEGVNLVGRDKTEVELIVQEKPFTVDISPGSQVAAQVGDSVVLTCAAVGCDSPSFSWRTQTDSPLNGEVRDEGATSTLTLSPVGVEDEHSYLCTVTCQRRKLEKTIQVEVYSFPEDPEIEISGPLVHGRPVTVNCTVPNVYPFDHLEIELLKGETTLLNKFLREEIGTKSLETKSLEMTFIPTAEDTGKALVCLAKLHSSQMESEPKQRQSTQTLYVNVAPKEPTIWVSPSPVPEEGSPVNLTCSSDGFPTPKILWSRQLKNGELQPLSQNTTLSFMATKMEDSGIYVCEGINEAGISKKSVELIIQGSSKDIQLTVFPSKSVKEGDTVIISCTCGSVPEIWIILKKKAKTGDMVLKSVNGSYTIRKAQLQDAGVYECESKTEVGSQLRSLTLDVKGKENNKDYFSPELLALYFASSLVIPAIGMIIYFARKANMKGSYSLVEAQKSKV", "length": 739 }, "evidence": [ { "id": "A0A8V0ZUA2", "url": "https://omabrowser.org/oma/group/A0A8V0ZUA2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "integrin binding", "id": "GO:0005178", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005178", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZUA2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUA2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZUA2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUA2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cell-cell adhesion", "id": "GO:0098609", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098609", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZUA2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUA2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 185, "end_pos": 187, "annotation": "n_glycosylation_sequon" }, { "start_pos": 227, "end_pos": 229, "annotation": "n_glycosylation_sequon" }, { "start_pos": 231, "end_pos": 233, "annotation": "n_glycosylation_sequon" }, { "start_pos": 301, "end_pos": 303, "annotation": "n_glycosylation_sequon" }, { "start_pos": 318, "end_pos": 320, "annotation": "n_glycosylation_sequon" }, { "start_pos": 392, "end_pos": 394, "annotation": "n_glycosylation_sequon" }, { "start_pos": 407, "end_pos": 409, "annotation": "n_glycosylation_sequon" }, { "start_pos": 423, "end_pos": 425, "annotation": "n_glycosylation_sequon" }, { "start_pos": 455, "end_pos": 457, "annotation": "n_glycosylation_sequon" }, { "start_pos": 462, "end_pos": 464, "annotation": "n_glycosylation_sequon" }, { "start_pos": 466, "end_pos": 468, "annotation": "n_glycosylation_sequon" }, { "start_pos": 51, "end_pos": 53, "annotation": "n_glycosylation_sequon" }, { "start_pos": 531, "end_pos": 533, "annotation": "n_glycosylation_sequon" }, { "start_pos": 77, "end_pos": 79, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZUA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUA2" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 7, "end_pos": 114, "start_aa": "Pro", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 185, "end_pos": 187 }, { "start_pos": 227, "end_pos": 229 }, { "start_pos": 231, "end_pos": 233 }, { "start_pos": 301, "end_pos": 303 }, { "start_pos": 318, "end_pos": 320 }, { "start_pos": 392, "end_pos": 394 }, { "start_pos": 407, "end_pos": 409 }, { "start_pos": 423, "end_pos": 425 }, { "start_pos": 455, "end_pos": 457 }, { "start_pos": 462, "end_pos": 464 }, { "start_pos": 466, "end_pos": 468 }, { "start_pos": 51, "end_pos": 53 }, { "start_pos": 531, "end_pos": 533 }, { "start_pos": 77, "end_pos": 79 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZUB5-1", "uniprot_ac": "A0A8V0ZUB5", "uniprot_id": "A0A8V0ZUB5_CHICK", "mass": { "chemical_mass": 15524.0, "monoisotopic_mass": 15524.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Secreted protein", "type": "recommended", "evidence": [ { "id": "A0A8V0ZUB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUB5/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZUB5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUB5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUB5", "locus": {} } ], "crossref": [ { "id": "A0A8V0ZUB5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZUB5", "database": "AlphaFoldDB", "categories": [] }, { "id": "A0A8V0ZUB5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUB5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZUB5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUB5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAVALLVLAFFFADPLVSGSLRLADVMEPVTLKKSSSRPCVLPWRLLLSLLTPLRMRSSLNCFSPHMNCTSSSSFGSVHFSSTSSGLMTSGSRKSFWASLCNQFSGKGYFLVSMCWMISSMVLCCLMSSTARLGPMPRMLSQ", "length": 142, "header": "tr|A0A8V0ZUB5-1|A0A8V0ZUB5_CHICK Isoform 1 of Secreted protein OS=Gallus gallus OX=9031 GN= PE=4 SV=2 CANONICAL=A0A8V0ZUB5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZUB5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUB5/entry#A0A8V0ZUB5-1", "sequence": { "sequence": "MAVALLVLAFFFADPLVSGSLRLADVMEPVTLKKSSSRPCVLPWRLLLSLLTPLRMRSSLNCFSPHMNCTSSSSFGSVHFSSTSSGLMTSGSRKSFWASLCNQFSGKGYFLVSMCWMISSMVLCCLMSSTARLGPMPRMLSQ", "length": 142, "header": "tr|A0A8V0ZUB5-1|A0A8V0ZUB5_CHICK Isoform 1 of Secreted protein OS=Gallus gallus OX=9031 GN= PE=4 SV=2 CANONICAL=A0A8V0ZUB5-1" }, "locus": { "chromosome": "5", "start_pos": 449415, "end_pos": 448990, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010057983.1", "url": 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"evidence": [ { "id": "A0A8V0ZUE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUE9" } ] }, { "name": "RILPL2", "type": "synonym", "evidence": [ { "id": "XP_046757205", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046757205" } ] } ], "protein_names": [ { "name": "RILP-like protein 2", "type": "recommended", "evidence": [ { "id": "A0A8V0ZUE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUE9/entry#names_and_taxonomy" } ] }, { "name": "RILP-like protein 2", "type": "synonym", "evidence": [ { "id": "XP_046757205", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046757205" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052546.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_046757205", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046757205" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZUE9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUE9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RILPL2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUE9", "locus": { "chromosome": "15", "start_pos": 5004225, "end_pos": 5000832, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010024741", "url": "https://www.ensembl.org/id/ENSGALG00010024741" } ] } } ], "crossref": [ { "id": "A0A8V0ZUE9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZUE9", "database": 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"database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZUE9", "url": "https://www.orthodb.org/?gene=A0A8V0ZUE9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21502", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21502", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21502:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21502:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF09744", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09744", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF11461", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11461", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_046757205", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046757205", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZUE9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUE9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZUE9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUE9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A3V5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3V5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A3V5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3V5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A3W5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3W5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A3W5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3W5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQRGGEGEEEEEDGEDDGGPESALQKSPFQLTAEDVYDISSVVGRDLLQLSAGPEVPAAAARLQFSMVRVLEMLEALVSEGSLTEEQLRMERDSLRAELEALRGRAAAGSAQQPNLGPDKMVIDLTDPNRPRFTLQELRDVLQERNQLKAQLLVVQEELQCYKSGIISQRKDQAKELEKEPCDSNPSTSKDSHEKTIIKRLFSFKHGK", "length": 208, "header": "tr|A0A8V0ZUE9-1|A0A8V0ZUE9_CHICK Isoform 1 of RILP-like protein 2 OS=Gallus gallus OX=9031 GN=RILPL2 PE=4 SV=1 CANONICAL=A0A8V0ZUE9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZUE9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUE9/entry#A0A8V0ZUE9-1", "sequence": { "sequence": "MQRGGEGEEEEEDGEDDGGPESALQKSPFQLTAEDVYDISSVVGRDLLQLSAGPEVPAAAARLQFSMVRVLEMLEALVSEGSLTEEQLRMERDSLRAELEALRGRAAAGSAQQPNLGPDKMVIDLTDPNRPRFTLQELRDVLQERNQLKAQLLVVQEELQCYKSGIISQRKDQAKELEKEPCDSNPSTSKDSHEKTIIKRLFSFKHGK", "length": 208, "header": "tr|A0A8V0ZUE9-1|A0A8V0ZUE9_CHICK Isoform 1 of RILP-like protein 2 OS=Gallus gallus OX=9031 GN=RILPL2 PE=4 SV=1 CANONICAL=A0A8V0ZUE9-1" }, "locus": { "chromosome": "15", "start_pos": 5003757, "end_pos": 5000884, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010060397.1", "url": "https://www.ensembl.org/id/ENSGALT00010060397.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010037156.1", "url": "https://www.ensembl.org/id/ENSGALP00010037156.1" } ] } }, { "isoform_ac": "A0A8V1A3V5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUE9/entry#A0A8V1A3V5-1", "sequence": { "sequence": "MQRGGEGEEEEEDGEDDGGPESALQKSPFQLTAEDVYDISSVVPAAAARLQFSMVRVLEMLEALVSEGSLTEEQLRMERDSLRAELEALRGRAAAGSAQQPNLGPDKMVIDLTDPNRPRFTLQELRDVLQERNQLKAQLLVVQEELQCYKSGIISQRKDQAKELEKEPCDSNPSTSKDSHEKTIIKRLFSFKHGK", "length": 195, "header": "tr|A0A8V1A3V5-1|A0A8V0ZUE9_CHICK Computationally mapped isoform of RILP-like protein 2 OS=Gallus gallus OX=9031 GN=RILPL2 PE=4 SV=1 CANONICAL=A0A8V0ZUE9-1" }, "locus": { "chromosome": "15", "start_pos": 5003757, "end_pos": 5000884, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010060395.1", "url": "https://www.ensembl.org/id/ENSGALT00010060395.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010037154.1", "url": "https://www.ensembl.org/id/ENSGALP00010037154.1" } ] } }, { "isoform_ac": "A0A8V1A3W5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUE9/entry#A0A8V1A3W5-1", "sequence": { "sequence": "MQRGGEGEEEEEDGEDDGGPESALQKSPFQLTAEDVYDISSVVGRDLLQLSAGPEVPAAAARLQFSMVRVLEMLEALVSEGSLTEEQLRMERDSLRAELEALRGRAAAGSAQQPNLGPDKMVIDLTDPNRPRFTLQELRDVLQERNQLKAQLLVVQEELQCYKSGIISQRKDQAKELEKEPCDSNPSTSKDSHEKTIIKRL", "length": 201, "header": "tr|A0A8V1A3W5-1|A0A8V0ZUE9_CHICK Computationally mapped isoform of RILP-like protein 2 OS=Gallus gallus OX=9031 GN=RILPL2 PE=4 SV=1 CANONICAL=A0A8V0ZUE9-1" }, "locus": { "chromosome": "15", "start_pos": 5003280, "end_pos": 5000884, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010060400.1", "url": "https://www.ensembl.org/id/ENSGALT00010060400.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010037159.1", "url": "https://www.ensembl.org/id/ENSGALP00010037159.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A4IFK7-1", "protein_name": "RILP-like protein 2", "gene_name": "RILPL2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MEEPPLREEEEEEEEDEAGPEGALGKSPLQLTAEDVYDISYVMGRELMALGSDPRVTQLQFKIVRVLEMLETLVNEGNLTVEELRMERDNLRKEVEGLRREGSAAGPEVNLGPDKMVVDLTDPNRPRFTLQELRDVLQERNKLKSQLLVVQEELQCYKSGLIPPREGPGGRREKEALFPRGSNANSNKEEKTIIRKLFSFRSGKQT", "length": 206 }, "evidence": [ { "id": "A0A8V0ZUE9", "url": "https://omabrowser.org/oma/group/A0A8V0ZUE9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZUE9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUE9" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZUE9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUE9" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZUE9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUE9" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZUE9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUE9" } ], "pmid": "" }, { "name": "ciliary basal body", "id": "GO:0036064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036064", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZUE9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUE9" } ], "pmid": "" }, { "name": "cilium", "id": "GO:0005929", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005929", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZUE9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUE9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZUE9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUE9" } ], "pmid": "" }, { "name": "protein dimerization activity", "id": "GO:0046983", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046983", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZUE9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUE9" } ], "pmid": "" }, { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZUE9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUE9" } ], "pmid": "" }, { "name": "dynein light intermediate chain binding", "id": "GO:0051959", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051959", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZUE9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUE9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "cilium assembly", "id": "GO:0060271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060271", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZUE9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUE9" } ], "pmid": "" }, { "name": "epithelial cell morphogenesis", "id": "GO:0003382", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003382", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZUE9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUE9" } ], "pmid": "" }, { "name": "protein transport from ciliary membrane to plasma membrane", "id": "GO:1903445", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903445", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZUE9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUE9" } ], "pmid": "" }, { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZUE9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUE9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZUE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUE9" }, { "id": "PS51776", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51776" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RH1", "eco_id": "ECO_0000259", "start_pos": 19, "end_pos": 105, "start_aa": "Gly", "end_aa": "Arg", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZUE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUE9" }, { "id": "PS51777", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51777" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RH2", "eco_id": "ECO_0000259", "start_pos": 130, "end_pos": 197, "start_aa": "Arg", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZUF6-1", "uniprot_ac": "A0A8V0ZUF6", "uniprot_id": "A0A8V0ZUF6_CHICK", "mass": { "chemical_mass": 83558.0, "monoisotopic_mass": 83558.0 }, "refseq": {}, "gene_names": [ { "name": "PMEL", "type": "recommended", "evidence": [ { "id": "A0A8V0ZUF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUF6" } ] } ], "protein_names": [ { "name": "Premelanosome protein", "type": "synonym", "evidence": [ { "id": "A0A8V0ZUF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUF6/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZUF6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUF6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PMEL", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUF6", "locus": { "chromosome": "34", "start_pos": 1339431, "end_pos": 1345613, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010024745", "url": "https://www.ensembl.org/id/ENSGALG00010024745" } ] } } ], "crossref": [ { "id": "A0A8V0ZUF6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZUF6", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00146", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00146", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000601", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000601", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022409", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022409", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035986", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035986", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045219", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045219", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046846", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046846", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR059017", "url": "https://www.ebi.ac.uk/interpro/entry/IPR059017", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZUF6", "url": "https://www.orthodb.org/?gene=A0A8V0ZUF6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11861", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11861", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11861:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11861:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00801", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00801", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF20433", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20433", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF26141", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26141", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZUF6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUF6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZUF6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUF6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAPSALMRRFWGLRSRCSTRCAWQKARPCSSWNRSWCRNSKTSRCLRLSRSRSAGSMRLHGAIVLLAALLALVTAQQRGGGRSRGGVKGSAWGGRPAPFRSWDTARYRPWQEGTARQNDCWRGGDVTFDISNDAPTLVGARATFSIALRFPGTQTVLPDGRVVWSQNCTVNGTRMLQGDPVYPEQLAEGSDGVFPDGQPFPRSAWGKRGRFVYVWWTWGRYWQVVDGATSQLTVGTDGVALGSYTMEVVVYHYRGRQRFIPIGHASTQFSITDQVPIAVDVTQLEVAAGDGGSFVRNRPVAFNVRLHDPSHYLRDADISYSWDFGDQSGTLISRSPTVTHTYLQAGSFAARLVLQAAIPLSSCGTSAPPVVDPTTGPVPSLGPTATQPVGPTGSGTATAPSNLTGSGTAAAPGTTAAPRASGAPAEPTGVSVAVLSDSAATEPLPDPVLSTAVADAAAGTDPTADPLPPTSVSSGGDAPGTVAPTAVEGSVAAGVGTAEDVAAATPGATAADVAVDTAGATDGDAVGPTAAATAESIADPTAGATDGDAVGATAESIADPTAGATDGDAVGPTAAATAESIADPTAGATAVSSGSATAGATAEPLLLVKRQAPEAEPTGCVLYRYGTFSTELNIVQGIESVAIVQVVPAAPEGSGNSVELTVTCEGSLPEEVCTVVADAECRTAQMQTCSAVAPAPGCQLVLRQDFNQSGLYCLNVSLANGNGLAVASTHVAVGGASPAASGTTLTVGLLWAPLIAAALGTAAYTYRRVKYSPLLPTAPTAPRPHSWLPPGATLRLLLRQAFGGAPSGESSPLLRANAV", "length": 819, "header": "tr|A0A8V0ZUF6-1|A0A8V0ZUF6_CHICK Isoform 1 of Premelanosome protein OS=Gallus gallus OX=9031 GN=PMEL PE=3 SV=1 CANONICAL=A0A8V0ZUF6-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZUF6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUF6/entry#A0A8V0ZUF6-1", "sequence": { "sequence": "MAPSALMRRFWGLRSRCSTRCAWQKARPCSSWNRSWCRNSKTSRCLRLSRSRSAGSMRLHGAIVLLAALLALVTAQQRGGGRSRGGVKGSAWGGRPAPFRSWDTARYRPWQEGTARQNDCWRGGDVTFDISNDAPTLVGARATFSIALRFPGTQTVLPDGRVVWSQNCTVNGTRMLQGDPVYPEQLAEGSDGVFPDGQPFPRSAWGKRGRFVYVWWTWGRYWQVVDGATSQLTVGTDGVALGSYTMEVVVYHYRGRQRFIPIGHASTQFSITDQVPIAVDVTQLEVAAGDGGSFVRNRPVAFNVRLHDPSHYLRDADISYSWDFGDQSGTLISRSPTVTHTYLQAGSFAARLVLQAAIPLSSCGTSAPPVVDPTTGPVPSLGPTATQPVGPTGSGTATAPSNLTGSGTAAAPGTTAAPRASGAPAEPTGVSVAVLSDSAATEPLPDPVLSTAVADAAAGTDPTADPLPPTSVSSGGDAPGTVAPTAVEGSVAAGVGTAEDVAAATPGATAADVAVDTAGATDGDAVGPTAAATAESIADPTAGATDGDAVGATAESIADPTAGATDGDAVGPTAAATAESIADPTAGATAVSSGSATAGATAEPLLLVKRQAPEAEPTGCVLYRYGTFSTELNIVQGIESVAIVQVVPAAPEGSGNSVELTVTCEGSLPEEVCTVVADAECRTAQMQTCSAVAPAPGCQLVLRQDFNQSGLYCLNVSLANGNGLAVASTHVAVGGASPAASGTTLTVGLLWAPLIAAALGTAAYTYRRVKYSPLLPTAPTAPRPHSWLPPGATLRLLLRQAFGGAPSGESSPLLRANAV", "length": 819, "header": "tr|A0A8V0ZUF6-1|A0A8V0ZUF6_CHICK Isoform 1 of Premelanosome protein OS=Gallus gallus OX=9031 GN=PMEL PE=3 SV=1 CANONICAL=A0A8V0ZUF6-1" }, "locus": { "chromosome": "34", "start_pos": 1345395, "end_pos": 1339548, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010060407.1", "url": "https://www.ensembl.org/id/ENSGALT00010060407.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010037166.1", "url": "https://www.ensembl.org/id/ENSGALP00010037166.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 374, "start_aa": "Thr", "end_pos": 374, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr374", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 392, "start_aa": "Thr", "end_pos": 392, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr392", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 505, "start_aa": "Thr", "end_pos": 505, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr505", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 529, "start_aa": "Thr", "end_pos": 529, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr529", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 573, "start_aa": "Thr", "end_pos": 573, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr573", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 8, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZUF6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUF6" } ], "pmid": "" }, { "name": "extracellular exosome", "id": "GO:0070062", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070062", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZUF6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUF6" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZUF6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUF6" } ], "pmid": "" }, { "name": "melanosome", "id": "GO:0042470", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042470", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZUF6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUF6" } ], "pmid": "" }, { "name": "multivesicular body membrane", "id": "GO:0032585", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032585", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZUF6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUF6" } ], "pmid": "" }, { "name": "multivesicular body, internal vesicle", "id": "GO:0097487", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097487", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZUF6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUF6" } ], "pmid": "" }, { "name": "melanosome membrane", "id": "GO:0033162", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033162", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZUF6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUF6" } ], "pmid": "" }, { "name": "cis-Golgi network membrane", "id": "GO:0033106", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033106", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZUF6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUF6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZUF6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUF6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "melanosome organization", "id": "GO:0032438", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032438", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZUF6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUF6" } ], "pmid": "" } ] } ] }, 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"reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUG4", "locus": {} } ], "crossref": [ { "id": "A0A8V0ZUG4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZUG4", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR000007", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000007", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005398", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005398", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018066", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018066", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025659", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025659", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR16517", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16517", "database": "PANTHER", 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"https://www.uniprot.org/uniprotkb/A0A8V0ZZM7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZZM7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZM7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZZN1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZN1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZZN1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZN1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A3X5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3X5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A3X5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3X5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKLRQLKLENQRALLEKKQKKKRLDPLMVQPNPEAKLHRSKPKGFEEQTPLVETPTTFHSAVVLHGIDRPVSFLKSEVQDLGNKLQTFSVGSSITAENADEENNGHVLTETLRNAHLQEILQKRGISGSLNFDEEDTEEEEEVSKRPASQSPHPESERPSSATIKKSFAEIGASCSPSHQTVAHLGEVENLEEFALRPAPHGITVKCRITRDKKGMDRGLFPTYYMHLEKDNNRKMFLLAGRKRKKSKTSNYIISVDPTDLSREGESFIGKLRSNLMGTKFTVYDHGVSPIKAQGEVEKAHTRQELAAVYYETNVLGFKGPRKMSVIIPGMNMHHKRIPVQPRNENESLLSKWQTKDLENLIELHNKAPVWNDDTQSYVLNFHGRVTQASVKNFQIVHDNDQSSSLPVATVKEESQCDEGFFSPTHSLKENNCQPGDEPCSFPETLCIKEEEGLQLGDWLSPFASTVTVKEEPDSFVPVSAVMEKKCFTILKSPSKGVSDALVIKRCERREMSRSRRKQHLALPCSEEPVLIFPESNEFDPFQLGADLPLLQENQPLENASQLRCLQEERGPFKTPVKEMFSKLPVSSTPCKVPATTTPPLGGLDPWKSALSAKRGNELDFSPVRTLPLPFTPCQENQDLLGFNSTPLKSPLPESSWELLNTESNDTVHSPLTSSPSFSHKSTKQLSLELPASGFTENRSLVEGLILDTMNDSLSKILLDISFPGLEDENLGTDISWSQLIPELK", "length": 745, "header": "tr|A0A8V0ZUG4-1|A0A8V0ZUG4_CHICK Isoform 1 of TUB like protein 3 OS=Gallus gallus OX=9031 GN= PE=3 SV=1 CANONICAL=A0A8V0ZUG4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZUG4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUG4/entry#A0A8V0ZUG4-1", "sequence": { "sequence": "MKLRQLKLENQRALLEKKQKKKRLDPLMVQPNPEAKLHRSKPKGFEEQTPLVETPTTFHSAVVLHGIDRPVSFLKSEVQDLGNKLQTFSVGSSITAENADEENNGHVLTETLRNAHLQEILQKRGISGSLNFDEEDTEEEEEVSKRPASQSPHPESERPSSATIKKSFAEIGASCSPSHQTVAHLGEVENLEEFALRPAPHGITVKCRITRDKKGMDRGLFPTYYMHLEKDNNRKMFLLAGRKRKKSKTSNYIISVDPTDLSREGESFIGKLRSNLMGTKFTVYDHGVSPIKAQGEVEKAHTRQELAAVYYETNVLGFKGPRKMSVIIPGMNMHHKRIPVQPRNENESLLSKWQTKDLENLIELHNKAPVWNDDTQSYVLNFHGRVTQASVKNFQIVHDNDQSSSLPVATVKEESQCDEGFFSPTHSLKENNCQPGDEPCSFPETLCIKEEEGLQLGDWLSPFASTVTVKEEPDSFVPVSAVMEKKCFTILKSPSKGVSDALVIKRCERREMSRSRRKQHLALPCSEEPVLIFPESNEFDPFQLGADLPLLQENQPLENASQLRCLQEERGPFKTPVKEMFSKLPVSSTPCKVPATTTPPLGGLDPWKSALSAKRGNELDFSPVRTLPLPFTPCQENQDLLGFNSTPLKSPLPESSWELLNTESNDTVHSPLTSSPSFSHKSTKQLSLELPASGFTENRSLVEGLILDTMNDSLSKILLDISFPGLEDENLGTDISWSQLIPELK", "length": 745, "header": "tr|A0A8V0ZUG4-1|A0A8V0ZUG4_CHICK Isoform 1 of TUB like protein 3 OS=Gallus gallus OX=9031 GN= PE=3 SV=1 CANONICAL=A0A8V0ZUG4-1" }, "locus": { "chromosome": "1", "start_pos": 75625972, "end_pos": 75604683, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010060417.1", "url": "https://www.ensembl.org/id/ENSGALT00010060417.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010037176.1", "url": "https://www.ensembl.org/id/ENSGALP00010037176.1" } ] } }, { "isoform_ac": "A0A8V0ZZM7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUG4/entry#A0A8V0ZZM7-1", "sequence": { "sequence": "MQYFSIFEDEGMKLRQLKLENQRALLEKKQKKKRLDPLMVQPNPEAKLHRSKPKGFEEQTPLVETPTTFHSAVVLHGIDRPVSFLKSEVQDLGNKLQTFSVGSSITAENADEENNGHVLTETLRNAHLQEILQKRGISGSLNFDEEDTEEEEEVSKRPASQSPHPESERPSSATIKKSFAEIGASCSPSHQTVAHLGEVENLEEFALRPAPHGITVKCRITRDKKGMDRGLFPTYYMHLEKDNNRKMFLLAGRKRKKSKTSNYIISVDPTDLSREGESFIGKLRSNLMGTKFTVYDHGVSPIKAQGEVEKAHTRQELAAVYYETNVLGFKGPRKMSVIIPGMNMHHKRIPVQPRNENESLLSKWQTKDLENLIELHNKAPVWNDDTQSYVLNFHGRVTQASVKNFQIVHDNDRKSLVESGGEGHLNRKNSIFHEVWEE", "length": 438, "header": "tr|A0A8V0ZZM7-1|A0A8V0ZUG4_CHICK Computationally mapped isoform of TUB like protein 3 OS=Gallus gallus OX=9031 GN= PE=3 SV=1 CANONICAL=A0A8V0ZUG4-1" }, "locus": { "chromosome": "1", "start_pos": 75620450, "end_pos": 75594436, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010060409.1", "url": "https://www.ensembl.org/id/ENSGALT00010060409.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010037168.1", "url": "https://www.ensembl.org/id/ENSGALP00010037168.1" } ] } }, { "isoform_ac": "A0A8V0ZZN1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUG4/entry#A0A8V0ZZN1-1", "sequence": { "sequence": "MKLRQLKLENQRALLEKKQKKKRLDPLMVQPNPEAKLHRSKPKGFEEQTPLVETPTTFHSAVVLHGIDRPVSFLKSEVQDLGNKLQTFSVGSSITAENADEENNGHVLTETLRNAHLQEILQKRGISGSLNFDEEDTEEEEEVSKRPASQSPHPESERPSSATIKKSFAEIGASCSPSHQTVAHLGEVENLEEFALRPAPHGITVKCRITRDKKGMDRGLFPTYYMHLEKDNNRKMFLLAGRKRKKSKTSNYIISVDPTDLSREGESFIGKLRSNLMGTKFTVYDHGVSPIKAQGEVEKAHTRQELAAVYYETNVLGFKGPRKMSVIIPGMNMHHKRIPVQPRNENESLLSKWQTKDLENLIELHNKAPVWNDDTQSYVLNFHGRVTQASVKNFQIVHDNDPDYIVMQFGRVAEDVFTLDYNYPLCALQAFAIGLSSFDSKLACE", "length": 445, "header": "tr|A0A8V0ZZN1-1|A0A8V0ZUG4_CHICK Computationally mapped isoform of TUB like protein 3 OS=Gallus gallus OX=9031 GN= PE=3 SV=1 CANONICAL=A0A8V0ZUG4-1" }, "locus": { "chromosome": "1", "start_pos": 75621004, "end_pos": 75604683, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010060414.1", "url": "https://www.ensembl.org/id/ENSGALT00010060414.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010037173.1", "url": "https://www.ensembl.org/id/ENSGALP00010037173.1" } ] } }, { "isoform_ac": "A0A8V1A3X5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUG4/entry#A0A8V1A3X5-1", "sequence": { "sequence": "MEGARSRCVLSGGSIFEDEGMKLRQLKLENQRALLEKKQKKKRLDPLMVQPNPEAKLHRSKPKGFEEQTPLVETPTTFHSAVVLHGIDRPVSFLKSEVQDLGNKLQTFSVGSSITAENADEENNGHVLTETLRNAHLQEILQKRGISGSLNFDEEDTEEEEEVSKRPASQSPHPESERPSSATIKKSFAEIGASCSPSHQTVAHLGEVENLEEFALRPAPHGITVKCRITRDKKGMDRGLFPTYYMHLEKDNNRKMFLLAGRKRKKSKTSNYIISVDPTDLSREGESFIGKLRSNLMGTKFTVYDHGVSPIKAQGEVEKAHTRQELAAVYYETNVLGFKGPRKMSVIIPGMNMHHKRIPVQPRNENESLLSKWQTKDLENLIELHNKAPVWNDDTQSYVLNFHGRVTQASVKNFQIVHDNDRKSLVESGGEGHLNRKNSIFHEVWEE", "length": 447, "header": "tr|A0A8V1A3X5-1|A0A8V0ZUG4_CHICK Computationally mapped isoform of TUB like protein 3 OS=Gallus gallus OX=9031 GN= PE=3 SV=1 CANONICAL=A0A8V0ZUG4-1" }, "locus": { "chromosome": "1", "start_pos": 75620450, "end_pos": 75591901, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010060410.1", "url": "https://www.ensembl.org/id/ENSGALT00010060410.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010037169.1", "url": "https://www.ensembl.org/id/ENSGALP00010037169.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-5610787", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5610787", "resource": "Reactome", "description": "Hedgehog 'off' state" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZUG4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUG4" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZUG4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUG4" } ], "pmid": "" }, { "name": "cilium", "id": "GO:0005929", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005929", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZUG4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUG4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "protein localization to cilium", "id": "GO:0061512", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061512", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZUG4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUG4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 346, "end_pos": 348, "annotation": "n_glycosylation_sequon" }, { "start_pos": 559, "end_pos": 561, "annotation": "n_glycosylation_sequon" }, { "start_pos": 644, "end_pos": 646, "annotation": "n_glycosylation_sequon" }, { "start_pos": 665, "end_pos": 667, "annotation": "n_glycosylation_sequon" }, { "start_pos": 698, "end_pos": 700, "annotation": "n_glycosylation_sequon" }, { "start_pos": 711, "end_pos": 713, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZUG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUG4" }, { "id": "PF01167", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01167" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Tubby C-terminal", "eco_id": "ECO_0000259", "start_pos": 197, "end_pos": 403, "start_aa": "Arg", "end_aa": "Ser", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZUG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUG4" }, { "id": "PF16322", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16322" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Tubby N-terminal", "eco_id": "ECO_0000259", "start_pos": 10, "end_pos": 177, "start_aa": "Asn", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 346, "end_pos": 348 }, { "start_pos": 559, "end_pos": 561 }, { "start_pos": 644, "end_pos": 646 }, { "start_pos": 665, "end_pos": 667 }, { "start_pos": 698, "end_pos": 700 }, { "start_pos": 711, "end_pos": 713 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZUI1-1", "uniprot_ac": "A0A8V0ZUI1", "uniprot_id": "A0A8V0ZUI1_CHICK", "mass": { "chemical_mass": 100610.0, "monoisotopic_mass": 100610.0 }, "refseq": { "ac": "XP_004941519", "name": "p53-induced death domain-containing protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004941519" }, "gene_names": [ { "name": "LRRC27", "type": "recommended", "evidence": [ { "id": "A0A8V0ZUI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUI1" } ] }, { "name": "LRRC27", "type": "synonym", "evidence": [ { "id": "XP_004941519", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004941519" } ] } ], "protein_names": [ { "name": "Leucine rich repeat containing 27", "type": "synonym", "evidence": [ { "id": "A0A8V0ZUI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUI1/entry#names_and_taxonomy" } ] }, { "name": "p53-induced death domain-containing protein 1", "type": "synonym", "evidence": [ { "id": "XP_004941519", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004941519" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052536.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004941519.3. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004941519", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004941519" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZUI1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUI1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LRRC27", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUI1", "locus": {} } ], "crossref": [ { "id": "A0A8V0ZUI1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZUI1", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd08779", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08779", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "426464", "url": "https://www.ncbi.nlm.nih.gov/gene/426464", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000488", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000488", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000906", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000906", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003591", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003591", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011029", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011029", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019502", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019502", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050216", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050216", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:426464", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:426464", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YPGGCHR", "url": "https://omabrowser.org/oma/group/YPGGCHR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZUI1", "url": "https://www.orthodb.org/?gene=A0A8V0ZUI1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48051", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48051", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR48051:SF39", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48051:SF39", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00531", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00531", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00791", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00791", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF10461", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10461", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13855", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13855", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004941519", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004941519", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZUI1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUI1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZUI1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUI1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQKMAELLKLGDEHGEGDPGAPSLSGSCLADNRLTLDVYPDGCRRLLRLFEGQQAEVVQVELLRLSSNDRLLDATLSILPHLKRLKSLVLRGGHVRDEFGSCQHGSLTSLPPDVGTLRCLTHLDLSFNSLSTLPSCIPSLTSLRMLLVSHNNLVALPENFGSLSKLTFFSAMKNQLKDLPQSIGELAALEDLDLSENVLELLPEEIGNLHSCTELDLSGNRLSSIPDSLANLKSLWRLHLHSNLLVTVPASLASLPNLCRLDLQNNCLRAVPPEIQTAPFVHLRGNPLGEAEPSLQADESSATELRRLFLASEEDSFTVTSEGCEVVLACGIRFYFPPEAASDPLQIYFRTLAPDPQWVKLRHHDVLLSKVLELQPHGVKFQQEVEIWMPYASPETLHQREVVVRTFSGQSWSDLRTQVEKKRKSKKHVAHCSVLHFSWFLVVSRLVQNECKVPTEGTLLFSSVDPNIKVTFPPGVTEETRNVKLQVLPVSAEEIAELTADAGCKASPLLCLSQDSLVDFLRPVRIQLPLPFGVTGLNLDRSRLHLLCGDVEGQTWDDITSQVVLEFTHLYAVFEVTHFSWYWLWYTTKTYIGGIAKKVYERLRMYQVNFIALQRRKDPEQVLLQCLPKHKVDTVLKKLQDRYRGPEPSDMVEMFEGEQFFAAFERGISIDMDRPDCVDGRLSFIFYSHLKNMKEIYVTSPVDRKGQAVKGQVSFYRGAVPESIPEDASRRRRGPDPLWLATLPIKLPRLKPRWGETSSSLNGFSFPPLNLGNAETGYLTQANLLSIARRVGADWQTIGLNLGLTYRQIERIGYNNREDLDKQILDMLFSWAQQNSGDPDCVSKLITAMKESGRQDIADEVEAIIELGRRKYRESIRRVGLEQESSTEDSAIAMT", "length": 895, "header": "tr|A0A8V0ZUI1-1|A0A8V0ZUI1_CHICK Isoform 1 of Leucine rich repeat containing 27 OS=Gallus gallus OX=9031 GN=LRRC27 PE=4 SV=1 CANONICAL=A0A8V0ZUI1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZUI1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUI1/entry#A0A8V0ZUI1-1", "sequence": { "sequence": "MQKMAELLKLGDEHGEGDPGAPSLSGSCLADNRLTLDVYPDGCRRLLRLFEGQQAEVVQVELLRLSSNDRLLDATLSILPHLKRLKSLVLRGGHVRDEFGSCQHGSLTSLPPDVGTLRCLTHLDLSFNSLSTLPSCIPSLTSLRMLLVSHNNLVALPENFGSLSKLTFFSAMKNQLKDLPQSIGELAALEDLDLSENVLELLPEEIGNLHSCTELDLSGNRLSSIPDSLANLKSLWRLHLHSNLLVTVPASLASLPNLCRLDLQNNCLRAVPPEIQTAPFVHLRGNPLGEAEPSLQADESSATELRRLFLASEEDSFTVTSEGCEVVLACGIRFYFPPEAASDPLQIYFRTLAPDPQWVKLRHHDVLLSKVLELQPHGVKFQQEVEIWMPYASPETLHQREVVVRTFSGQSWSDLRTQVEKKRKSKKHVAHCSVLHFSWFLVVSRLVQNECKVPTEGTLLFSSVDPNIKVTFPPGVTEETRNVKLQVLPVSAEEIAELTADAGCKASPLLCLSQDSLVDFLRPVRIQLPLPFGVTGLNLDRSRLHLLCGDVEGQTWDDITSQVVLEFTHLYAVFEVTHFSWYWLWYTTKTYIGGIAKKVYERLRMYQVNFIALQRRKDPEQVLLQCLPKHKVDTVLKKLQDRYRGPEPSDMVEMFEGEQFFAAFERGISIDMDRPDCVDGRLSFIFYSHLKNMKEIYVTSPVDRKGQAVKGQVSFYRGAVPESIPEDASRRRRGPDPLWLATLPIKLPRLKPRWGETSSSLNGFSFPPLNLGNAETGYLTQANLLSIARRVGADWQTIGLNLGLTYRQIERIGYNNREDLDKQILDMLFSWAQQNSGDPDCVSKLITAMKESGRQDIADEVEAIIELGRRKYRESIRRVGLEQESSTEDSAIAMT", "length": 895, "header": "tr|A0A8V0ZUI1-1|A0A8V0ZUI1_CHICK Isoform 1 of Leucine rich repeat containing 27 OS=Gallus gallus OX=9031 GN=LRRC27 PE=4 SV=1 CANONICAL=A0A8V0ZUI1-1" }, "locus": { "chromosome": "5", "start_pos": 15397295, "end_pos": 15384460, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056345.1", "url": "https://www.ensembl.org/id/ENSGALT00010056345.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034113.1", "url": "https://www.ensembl.org/id/ENSGALP00010034113.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:426464", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:426464", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1RYY9-1", "protein_name": "p53-induced death domain-containing protein 1", "gene_name": "PIDD1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MCAGRSGQNRGTGRLEPPWVLPAQACLASWDMSGPRGQPVCDGCSGGGQEPEPSAAEDAARDATDAVAVGPGTLPLLAGNRLSLDLYPRGCHRLLHLCAQQVPQLLEVEFLQLSGHEDPRLLEATLAQLPSSLPHLRSLVVKGGQHRDAQGACLRGSLATLPAGLNGLVRLAHLDLSFNSLETLPACVPQMCGLGALLLSHNCLSELPEALGALCALTFLAVTHNRLQTLPTALGSLSTLQRLDLSENLLDTLPPEIGGLSSLAELNLASNRLQSLPASLAGLRSLQLLVLHSNLLASVPAGLARLPLLTRLDLRDNQLRDVPPELLDAPFVRLQGNPLSGSPPTPRSPPGTPVVPKMPSLLLSSDLDSFAVTPLGCSVTLTCGVRLRFPAGATATPVTVRYRLWLPEPRLVPLGPHDSLLSGVLELQPHGVAFQQEVGLWLLFVPPRARRCREVVVRTLSDNSWSDLETHLEEEAPKRLWAHCQVPHFSWFLVVSRPVSDACLVPPEGTLLCSSGHPGVKVTFPPGATEEPRHVRMQVVRVGSRELPALLREPEAAASPLLCLSQSGPLSFLRPVTVQLPLPPGITGLSLDRSCLHLLHRAPPAATWDDITAQVALELTHLYARFQVTRFSWYWLWYTTKACVGGLARKAWERLRLHRVNLIALQRRRDPEQVLLQCLPRHKVDATLRRLLERYRGPEPSDTVEVFEGEKFFAAFERGIAVDADRPDCVEGRVCFVFYSHLKNLKEVYVTTALDRRAQAVRGQVSFYRGEVPAEVPEEAEAARQRRGADALWMATLPIKLPRLRGSEEPAQGPGLSLAPLNLGDAETGFLTQSNLLNVAGRLGPDWPAVALHLGVPYRQLQRIRHEFRDDLDGQIRHMLFSWAERQAGQPGAVGLLVQALEQSDRRDVAEEVRAVLELGRRKYQEGIRRTSLAPGDLALRGPSSSPSPEPAQA", "length": 954 }, "evidence": [ { "id": "A0A8V0ZUI1", "url": "https://omabrowser.org/oma/group/A0A8V0ZUI1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G5E5N0-1", "protein_name": "p53-induced death domain-containing protein 1", "gene_name": "PIDD1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAAMEAGPVPATLAQEDAARDASEAAGAGPEAPLLPAGNRLSLHLHPGGCRRLLRLCAQQAPQLLEVDFLQLSGHEDPQLLEAALARLPWSLPRLRSLVLKGGQRREALGACLRGSLATLPASLSSLARLAHLDLSFNSLETLPACVPQMCGLDALLLSRNCLSELPAALGALPALTFLAVTHNRLRTLPPALGALSSLQRLDLSGNLLEALPPEIGGLGSLAELNLASNRLQSLPSSLAGLRALRLFILHSNLLASVPASLARLPLLTRLDLRDNQLRDVPPELLDAPFVRLQGNPLGRPPPDPPSPPGPPVVPEMPRLLLTSDRDSFAVTPQGCSVTLACGVRLQFPAGATAAPMTIRYRLWLPEPRLVPLGPHDALLSGVLELQPHGVAFQQEVGLWLLFVPPRARRCREVVVRTLSDNSWSDLETHLEEETPKRLWAHCQVPHFSWFLVVSRPVSDACLVPPEGTLLCSSGHAGVRVTFPAGATEEPRHVRMQVVRVGSRELPALLGEPEAASSPLLCLSQSGPSSFLRPVTIQLPLPPGVTGLSLDRARLHLLHRAAPAAAWDDITAQVALELTHLYARFQVTRFSWYWLWYTTKACVGSLARKAWERLRLYRVNLIALQRRRDPEQVLLQCLPRNKVDATLRRLLERYRGPEPSDTVEMFEGEKFFAAFERGIDIDADRPDCVEGRLCFVFYSHLKNLKEVYVTTALDRRARAVRGQVSFYRGEVPEVVPEEAEAARQKRGPAALWMATLPIKLPRLQGCEGPTREPGLSLAPLNLGDAETGFLTQSNLLNVAGRLGPDWPAVALHLGLPYRELQRIRHEFRDDLDGQIRHMLFSWAERQAGQPGAVGRLVQALEQSDRRDVAEEVRAVLELGRRKYQEGIRHTSLAPGNLTSPDRLPSPSPEPAQA", "length": 913 }, "evidence": [ { "id": "A0A8V0ZUI1", "url": "https://omabrowser.org/oma/group/A0A8V0ZUI1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "M0R797-1", "protein_name": "p53-induced death domain-containing protein 1", "gene_name": "Pidd1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAVLEGPKPEETAAAAEDAARPTVEAVASRPGVPILLAGNQLNLDLRPGGCRRLQYLCSQQHTQLLQVEFLRLSTHEDPRLLDDTLAKVPWSLLRLRSLVLKGGQSRGALGACLHGTLTTLPASMRDLACLAHLDLSFNRLETLPTCVLELHSLDALLLSHNCLSELPEALGALPTLTFLTVTHNLLERLPPTLGSLSTLQRLDLSENLLDTIPSEIGDLSSLRELNLASNRLQHLPASLAGLRSLRLLVLHSNLLTSVPPGLAHLPLITRLDLRDNQLRDLPAELLDAPFVRLQGNPLGEASPAPPSPPDISQVPEMPRLFLTSDLDSFLVTPHGCSVTLACGVRLQFPAGATTTPITIHYRLWLPEPGLVSLGPHDFLLSGVLELQPHGVAFQQNVSLWLLFVPPRVRVRRCREVVVRTRSDNIWNDLETHLEEEAPKRRWARCQVPHFSWFLVVLRPVSNTCLLPPEGALLCSSGHPGVKVTFPPGVTEEPRQVSMQVVHMAGLELRALLEESEAAVSPLLCLSQSGPPSFLQPVTVQLPLPPGVTGFSLDRSHLHLLYRTPLTSTWDDISTQVALEFTHLYARFQVTHFSWYWLWYTTKTCVGGLARKAWERLRLHRVNLIALQRRRDPEQVLLQCLPRSKVDATLSRLLDRYRGPEPSETVEMFEGEKFFAAFERGIDVDADRPDCVDGRICFVFYSHLKNMKEVYITTALDREAQDVRGQVSFYRGSLPMEVPEEAEAARRRKGTDALWMATLPIKLPRLRGAQGSGQGTDFSLMPLNLGDAETGFLTQSNLLSVASRLGSDWPTVALHLGMPYRKLQRIRHEFRDDLDGQIRHMLFSWAESQTGQPGAVGHLVQALEQSDRQDVAEEVRAILELGRHKYQDSIRRTGLAPEDSTLPSTSALQNPESAQA", "length": 917 }, "evidence": [ { "id": "A0A8V0ZUI1", "url": "https://omabrowser.org/oma/group/A0A8V0ZUI1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9ERV7-1", "protein_name": "p53-induced death domain-containing protein 1", "gene_name": "Pidd1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAVLEGQEPEETAAAAEDAATSTLEAVDAGPGAPFLPAGNQLNLDLRPGGCHRLQYLCSQQPPQLLQVEFLRLSTHEDPQLLDDTLAKVPWSLLRLRSLVLKGGQSRGALGACLHGTLTTLPAGLSDLACLAHLDLSFNRLETLPTCVPELHGLDALLLSHNHLSELPEALGALPALTFLTVTHNRLERLPLTLGSLSTLQRLDLSENLLDTIPSEIGNLRSLSELNLASNRLQSLPASLAGLRSLRLLVLHSNLLTSVPTGLVHLPLITRLDLRDNRLRDLPAELLDAPFVRLQGNPLGEASPAPPSPPDISQVPEMPRLLLTSDLDSFLVTPHGCSVTLACGVRLQFPAGATTTPVTIHYRLWLPEPGLVSLGPHDFLLSSVLELQPHGVAFQQDVSLWLLFVPPRVRRCREVVVRTRSNNTWNDLETQLEEEAPKRLWARCQVPHFSWFLVVLRPVSNTCLLPPEGALLCSSGHPGVRVTFPPGVTEEPRQVSMQVVHMAGLELRTLLEESEASVSPLLCLSQSGPPSFLQPVTVQLPLPPGVTGFSLDRSHLHLLYRTPLTTTWDDITTQVALEFTHLYARFQVTHFSWYWLWYTTKTCVGGLARKAWERLRLHRVNLIALQRRRDPEQVLLQCLPRNKVDATLSRLLVRYRGPEPSETVEMFEGEKFFAAFERGIDVDADRPDCVDGRICFVFYSHLKNVKEVYITTALDREAQDVRGQVSFYRGSLPVEVPAEAEAARQRKGTDALWMATLPIKLPRLRGAQGSGQGTDFSLMPLNLGDAETGFLTQSNLLSVASRLGPDWPAVALHLGMPYHKLQRIRHEFRDDLDGQVRHMLFSWAERQTGQPGAVGHLVQALEQSDRRDVAEEVRAILELGRHKYQDSIRRTGLAPEDSTLPGTSASQTPESAQA", "length": 915 }, "evidence": [ { "id": "A0A8V0ZUI1", "url": "https://omabrowser.org/oma/group/A0A8V0ZUI1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9HB75-1", "protein_name": "p53-induced death domain-containing protein 1", "gene_name": "PIDD1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAATVEGPELEAAAAAGDASEDSDAGSRALPFLGGNRLSLDLYPGGCQQLLHLCVQQPLQLLQVEFLRLSTHEDPQLLEATLAQLPQSLSCLRSLVLKGGQRRDTLGACLRGALTNLPAGLSGLAHLAHLDLSFNSLETLPACVLQMRGLGALLLSHNCLSELPEALGALPALTFLTVTHNRLQTLPPALGALSTLQRLDLSQNLLDTLPPEIGGLGSLLELNLASNRLQSLPASLAGLRSLRLLVLHSNLLASVPADLARLPLLTRLDLRDNQLRDLPPELLDAPFVRLQGNPLGEASPDAPSSPVAALIPEMPRLFLTSDLDSFPVTPQGCSVTLACGVRLQFPAGATATPITIRYRLLLPEPGLVPLGPHDALLSHVLELQPHGVAFQQDVGLWLLFTPPQARRCREVVVRTRNDNSWGDLETYLEEEAPQRLWAHCQVPHFSWFLVVSRPVSNACLVPPEGTLLCSSGHPGVKVIFPPGATEEPRRVSMQVVRMAGRELQALLGEPEAAVSPLLCLSQSGPPSFLQPVTVQLPLPSGITGLSLDRSRLHLLYWAPPAATWDDITAQVVLELTHLYARFQVTHFSWYWLWYTTKNCVGGLARKAWERLRLHRVNLIALQRRRDPEQVLLQCLPRNKVDATLRRLLERYRGPEPSDTVEMFEGEEFFAAFERGIDVDADRPDCVEGRICFVFYSHLKNVKEVYVTTTLDREAQAVRGQVSFYRGAVPVRVPEEAEAARQRKGADALWMATLPIKLPRLRGSEGPRRGAGLSLAPLNLGDAETGFLTQSNLLSVAGRLGLDWPAVALHLGVSYREVQRIRHEFRDDLDEQIRHMLFSWAERQAGQPGAVGLLVQALEQSDRQDVAEEVRAVLELGRRKYQDSIRRMGLAPKDPALPGSSAPQPPEPAQA", "length": 910 }, "evidence": [ { "id": "A0A8V0ZUI1", "url": "https://omabrowser.org/oma/group/A0A8V0ZUI1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "endopeptidase activity", "id": "GO:0004175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004175", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZUI1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUI1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZUI1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUI1" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZUI1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUI1" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZUI1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUI1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "negative regulation of apoptotic process", "id": "GO:0043066", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043066", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZUI1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUI1" } ], "pmid": "" }, { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZUI1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUI1" } ], "pmid": "" }, { "name": "protein autoprocessing", "id": "GO:0016540", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016540", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZUI1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUI1" } ], "pmid": "" }, { "name": "regulation of canonical NF-kappaB signal transduction", "id": "GO:0043122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043122", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZUI1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUI1" } ], "pmid": "" }, { "name": "DNA damage response, signal transduction by p53 class mediator", "id": "GO:0030330", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030330", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZUI1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUI1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZUI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUI1" }, { "id": "PS50017", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50017" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Death", "eco_id": "ECO_0000259", "start_pos": 780, "end_pos": 865, "start_aa": "Thr", "end_aa": "Ile", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZUI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUI1" }, { "id": "PS51145", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51145" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "ZU5", "eco_id": "ECO_0000259", "start_pos": 313, "end_pos": 446, "start_aa": "Glu", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZUJ6-1", "uniprot_ac": "A0A8V0ZUJ6", "uniprot_id": "A0A8V0ZUJ6_CHICK", "mass": { "chemical_mass": 149131.0, "monoisotopic_mass": 149131.0 }, "refseq": { "ac": "XP_015134386", "name": "cingulin-like protein 1 isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015134386" }, "gene_names": [ { "name": "CGNL1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZUJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUJ6" } ] }, { "name": "CGNL1", "type": "synonym", "evidence": [ { "id": "XP_015134386", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015134386" } ] } ], "protein_names": [ { "name": "Cingulin like 1", "type": "synonym", "evidence": [ { "id": "A0A8V0ZUJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUJ6/entry#names_and_taxonomy" } ] }, { "name": "cingulin-like protein 1 isoform X3", "type": "synonym", "evidence": [ { "id": "XP_015134386", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015134386" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052541.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015134386.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015134386", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015134386" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZUJ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUJ6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CGNL1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUJ6", "locus": { "chromosome": "10", "start_pos": 7336475, "end_pos": 7390713, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010023126", "url": "https://www.ensembl.org/id/ENSGALG00010023126" } ] } } ], "crossref": [ { "id": "415405", "url": "https://www.ncbi.nlm.nih.gov/gene/415405", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002928", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002928", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:415405", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415405", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZL82", "url": "https://www.orthodb.org/?gene=A0A8V0ZL82", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZUJ6", "url": "https://www.orthodb.org/?gene=A0A8V0ZUJ6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46349", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46349", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46349:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46349:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01576", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01576", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015134386", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015134386", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZL82", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL82", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZL82-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL82-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZUJ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUJ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZUJ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUJ6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEPYFAGFTQQDYEVTLELASEEIQKNRNGQNSKTGSYGVSIRVQGIDGHPYIVLNNTEGCLSENPPPSGKEHQVISQTISQSITDSNTAFKLEDKNSERKDFPGTQHMQPCTFKSLKITNPDENESGISDFKDGALKSPNLLNFQRHPELLQPYDPEKNNLNLENCQSSVCSKSTSLANEDKSEGKPWISSSKVISLQKTNTYFAESTKANSKKIYLNRTVDTEEQNKQVLDCPGSIISPSEVGVSESFSSTGRSPCLSPAAYPEARKPRPDVLPFRRQDSSGPVLDSRRSSSSSATPTSANSLYRFLLDDQEYAIYADNVNRHENRRYIPFLPGTGRDIDTGSLPGVDQLIEKFDKKVDFHKRGRPGKRNRIHPDDRKRSRSVDSALSLELDMTSDYLGEVSKSLGKSTEHLRKPSEVCFQKQFSRDQKAPSKEMKISARSIGRLQMPGKDSQNSHFSSLQHLKQNGDNTESFMIRSSTLPGQKKREEAKTVTSTLLLPNRNTIPPDSGAKKISLKTFSSVPSIQATPDLLKGQQDVAHQTNEETAKQILYNYLKEGSADNDDATKRKVNLVFEKIQTLKSRAAGKTQVSDTSAEVKALVEQKTELERKVEELQKKLDLEITNQQNCKEERDATRASLQDLQLRLDESISEKDALKKQLEENEKELRQNLEELFQVKMEQEKHQTEIRDLQDQLSEMHDELDNAKHTDEREKEVLIEELMQMKQDLQEILIAKDQQEEILRKRERELTALKGALKEEVSSHDMEMDKLKEQHDKEVLNLQQSLEKATENAAVLASERDAVEEVRNSIENQVKKLTEANTQLKRTVDELETKNEELHKQFDSMKGEENSMKEKLKRYKDENQQLEEALKYAEKEAKELMALKTSLENQLENVQENIRCISQERQHLTEQLKDETHQKEQLEKIKNEMENERWQLNKTVEKLQEELAEMVEASRTSAVELQNQLDEYKEKNRRELADMQRQLKEKNLEVEKSRLTAIRMQDEMRLLEENLRDHQRAQDEAITKTQLLEQTVKGLEYELEAKNHLKDDRARQIKLMEDKLSHLELELDEEKNNSDLLSERISRCREQIEQMRTELLQERATKQDLECDKISLERQNKDLRSRILHLESSYRSSKEGLVAQMEARITELEERLENEERDRANFQLSNRRLERKVKELMLQVDDEHLSLTDQKDQLSLRLKAMKRQVEEAEEEIDRLESAKKKLQRDLEEQLDMNEQLQGQLNAAKKELSRRKKSPSKVLTDFDDDDDDDDDFSTDGDSLCEAPSGNNFSKDNDTII", 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"MEPYFAGFTQQDYEVTLELASEEIQKNRNGQNSKTGSYGVSIRVQGIDGHPYIVLNNTEGCLSENPPPSGKEHQVISQTISQSITDSNTAFKLEDKNSERKDFPGTQHMQPCTFKSLKITNPDENESGISDFKDGALKSPNLLNFQRHPELLQPYDPEKNNLNLENCQSSVCSKSTSLANEDKSEGKPWISSSKVISLQKTNTYFAESTKANSKKIYLNRTVDTEEQNKQVLDCPGSIISPSEVGVSESFSSTGRSPCLSPAAYPEARKPRPDVLPFRRQDSSGPVLDSRRSSSSSATPTSANSLYRFLLDDQEYAIYADNVNRHENRRYIPFLPGTGRDIDTGSLPGVDQLIEKFDKKVDFHKRGRPGKRNRIHPDDRKRSRSVDSALSLELDMTSDYLGEVSKSLGKSTEHLRKPSEVCFQKQFSRDQKAPSKEMKISARSIGRLQMPGKDSQNSHFSSLQHLKQNGDNTESFMIRSSTLPGQKKREEAKTVTSTLLLPNRNTIPPDSGAKKISLKTFSSVPSIQATPDLLKGQQDVAHQTNEETAKQILYNYLKEGSADNDDATKRKVNLVFEKIQTLKSRAAGKTQVSDTSAEVKALVEQKTELERKVEELQKKLDLEITNQQNCKEERDATRASLQDLQLRLDESISEKDALKKQLEENEKELRQNLEELFQVKMEQEKHQTEIRDLQDQLSEMHDELDNAKHTDEREKEVLIEELMQMKQDLQEILIAKDQQEEILRKRERELTALKGALKEEVSSHDMEMDKLKEQHDKEVLNLQQSLEKATENAAVLASERDAVEEVRNSIENQVKKLTEANTQLKRTVDELETKNEELHKQFDSMKGEENSMKEKLKRYKDENQQLEEALKYAEKEAKELMALKTSLENQLENVQENIRCISQERQHLTEQLKDETHQKEQLEKIKNEMENERWQLNKTVEKLQEELAEMVEASRTSAVELQNQLDEYKEKNRRELADMQRQLKEKNLEVEKSRLTAIRMQDEMRLLEENLRDHQRAQDEAITKTQLLEQTVKGLEYELEAKNHLKDDRARQIKLMEDKLSHLELELDEEKNNSDLLSERISRCREQIEQMRTELLQERATKQDLECDKISLERQNKDLRSRILHLESSYRSSKEGLVAQMEARITELEERLENEERDRANFQLSNRRLERKVKELMLQVDDEHLSLTDQKDQMLEE", "length": 1196, "header": "tr|A0A8V0ZL82-1|A0A8V0ZL82_CHICK Computationally mapped isoform of Cingulin like 1 OS=Gallus gallus OX=9031 GN=CGNL1 PE=1 SV=1 CANONICAL=A0A8V0ZUJ6-1" }, "locus": { "chromosome": "10", "start_pos": 7378653, "end_pos": 7339408, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056362.1", "url": "https://www.ensembl.org/id/ENSGALT00010056362.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034125.1", "url": "https://www.ensembl.org/id/ENSGALP00010034125.1" } ] } }, { "isoform_ac": "A0A8V0ZUJ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUJ6/entry#A0A8V0ZUJ6-1", "sequence": { "sequence": "MEPYFAGFTQQDYEVTLELASEEIQKNRNGQNSKTGSYGVSIRVQGIDGHPYIVLNNTEGCLSENPPPSGKEHQVISQTISQSITDSNTAFKLEDKNSERKDFPGTQHMQPCTFKSLKITNPDENESGISDFKDGALKSPNLLNFQRHPELLQPYDPEKNNLNLENCQSSVCSKSTSLANEDKSEGKPWISSSKVISLQKTNTYFAESTKANSKKIYLNRTVDTEEQNKQVLDCPGSIISPSEVGVSESFSSTGRSPCLSPAAYPEARKPRPDVLPFRRQDSSGPVLDSRRSSSSSATPTSANSLYRFLLDDQEYAIYADNVNRHENRRYIPFLPGTGRDIDTGSLPGVDQLIEKFDKKVDFHKRGRPGKRNRIHPDDRKRSRSVDSALSLELDMTSDYLGEVSKSLGKSTEHLRKPSEVCFQKQFSRDQKAPSKEMKISARSIGRLQMPGKDSQNSHFSSLQHLKQNGDNTESFMIRSSTLPGQKKREEAKTVTSTLLLPNRNTIPPDSGAKKISLKTFSSVPSIQATPDLLKGQQDVAHQTNEETAKQILYNYLKEGSADNDDATKRKVNLVFEKIQTLKSRAAGKTQVSDTSAEVKALVEQKTELERKVEELQKKLDLEITNQQNCKEERDATRASLQDLQLRLDESISEKDALKKQLEENEKELRQNLEELFQVKMEQEKHQTEIRDLQDQLSEMHDELDNAKHTDEREKEVLIEELMQMKQDLQEILIAKDQQEEILRKRERELTALKGALKEEVSSHDMEMDKLKEQHDKEVLNLQQSLEKATENAAVLASERDAVEEVRNSIENQVKKLTEANTQLKRTVDELETKNEELHKQFDSMKGEENSMKEKLKRYKDENQQLEEALKYAEKEAKELMALKTSLENQLENVQENIRCISQERQHLTEQLKDETHQKEQLEKIKNEMENERWQLNKTVEKLQEELAEMVEASRTSAVELQNQLDEYKEKNRRELADMQRQLKEKNLEVEKSRLTAIRMQDEMRLLEENLRDHQRAQDEAITKTQLLEQTVKGLEYELEAKNHLKDDRARQIKLMEDKLSHLELELDEEKNNSDLLSERISRCREQIEQMRTELLQERATKQDLECDKISLERQNKDLRSRILHLESSYRSSKEGLVAQMEARITELEERLENEERDRANFQLSNRRLERKVKELMLQVDDEHLSLTDQKDQLSLRLKAMKRQVEEAEEEIDRLESAKKKLQRDLEEQLDMNEQLQGQLNAAKKELSRRKKSPSKVLTDFDDDDDDDDDFSTDGDSLCEAPSGNNFSKDNDTII", "length": 1294, "header": "tr|A0A8V0ZUJ6-1|A0A8V0ZUJ6_CHICK Isoform 1 of Cingulin like 1 OS=Gallus gallus OX=9031 GN=CGNL1 PE=1 SV=1 CANONICAL=A0A8V0ZUJ6-1" }, "locus": { "chromosome": "10", "start_pos": 7378653, "end_pos": 7338473, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056365.1", "url": "https://www.ensembl.org/id/ENSGALT00010056365.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034128.1", "url": "https://www.ensembl.org/id/ENSGALP00010034128.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 298, "start_aa": "Thr", "end_pos": 298, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr298", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:415405", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415405", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "protein localization to cell-cell junction", "id": "GO:0150105", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0150105", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZUJ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUJ6" } ], "pmid": "" }, { "name": "actin filament organization", "id": "GO:0007015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007015", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZUJ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUJ6" } ], "pmid": "" }, { "name": "negative regulation of small GTPase mediated signal transduction", "id": "GO:0051058", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051058", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZUJ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUJ6" } ], "pmid": "" }, { "name": "negative regulation of stress fiber assembly", "id": "GO:0051497", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051497", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZUJ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUJ6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "bicellular tight junction", "id": "GO:0005923", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005923", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZUJ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUJ6" } ], "pmid": "" }, { "name": "myosin complex", "id": "GO:0016459", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016459", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZUJ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUJ6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1071, "end_pos": 1073, "annotation": "n_glycosylation_sequon" }, { "start_pos": 125, "end_pos": 127, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1285, "end_pos": 1287, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1290, "end_pos": 1292, "annotation": "n_glycosylation_sequon" }, { "start_pos": 219, "end_pos": 221, "annotation": "n_glycosylation_sequon" }, { "start_pos": 56, "end_pos": 58, "annotation": "n_glycosylation_sequon" }, { "start_pos": 936, "end_pos": 938, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZUJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUJ6" }, { "id": "PF01576", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01576" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Myosin tail", "eco_id": "ECO_0000259", "start_pos": 588, "end_pos": 1016, "start_aa": "Lys", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 298 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1071, "end_pos": 1073 }, { "start_pos": 125, "end_pos": 127 }, { "start_pos": 1285, "end_pos": 1287 }, { "start_pos": 1290, "end_pos": 1292 }, { "start_pos": 219, "end_pos": 221 }, { "start_pos": 56, "end_pos": 58 }, { "start_pos": 936, "end_pos": 938 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 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"https://www.uniprot.org/uniprotkb/A0A1D5NW85" } ], "pmid": "" }, { "name": "linoleic acid binding", "id": "GO:0070539", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070539", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NW85", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NW85" } ], "pmid": "" }, { "name": "stearic acid binding", "id": "GO:0070540", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070540", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NW85", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NW85" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NW85", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NW85" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 158, "end_pos": 160, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5NW85-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 178, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5NW85-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5NW85" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A1D5NW85", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NW85" }, { "id": "PF00061", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00061" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Lipocalin/cytosolic fatty-acid binding", "eco_id": "ECO_0000259", "start_pos": 31, "end_pos": 166, "start_aa": "Ala", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 158, "end_pos": 160 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", 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0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A1D5NXF3-1", "uniprot_ac": "A0A1D5NXF3", "uniprot_id": "A0A1D5NXF3_CHICK", "mass": { "chemical_mass": 78059.0, "monoisotopic_mass": 78059.0 }, "refseq": { "ac": "NP_001257807", "name": "T-box transcription factor TBX3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001257807" }, "gene_names": [ { "name": "TBX3", "type": "recommended", "evidence": [ { "id": "A0A1D5NXF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NXF3" } ] }, { "name": "TBX3", "type": "synonym", "evidence": [ { "id": "NP_001257807", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001257807" } ] } ], "protein_names": [ { "name": "T-Box protein 3", "type": "synonym", "evidence": [ { "id": "NP_001257807", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001257807" } ] }, { "name": "T-box 3", "type": "synonym", "evidence": [ { "id": "NP_001257807", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001257807" } ] }, { "name": "T-box transcription factor 3", "type": "synonym", "evidence": [ { "id": "A0A1D5NXF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NXF3/entry#names_and_taxonomy" } ] }, { "name": "T-box transcription factor TBX3", "type": "synonym", "evidence": [ { "id": "NP_001257807", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001257807" } ] } ], "function": [ { "annotation": "Misexpression of Tbx2 and Tbx3 induced posterior homeotic transformation of digit III to digit IV and digit II to digit III, respectively. Erratum:[Dev Cell. 2005 Jun;8(6):971-2]", "evidence": [ { "database": "RefSeq", "id": "NP_001257807", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001257807" }, { "database": "PubMed", "id": "14723846", "url": "https://glygen.org/publication/PubMed/14723846" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NXF3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NXF3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TBX3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NXF3", "locus": { "chromosome": "15", "start_pos": 12225406, "end_pos": 12213494, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010000443", "url": "https://www.ensembl.org/id/ENSGALG00010000443" } ] } } ], "crossref": [ { "id": "A0A1D5NXF3", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5NXF3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000036043", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000036043", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd20188", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20188", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "374202", "url": "https://www.ncbi.nlm.nih.gov/gene/374202", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001699", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001699", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002070", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002070", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008967", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008967", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018186", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018186", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022582", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022582", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036960", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036960", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046360", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046360", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048387", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048387", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:374202", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:374202", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QGIAMSP", "url": "https://omabrowser.org/oma/group/QGIAMSP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5NXF3", "url": "https://www.orthodb.org/?gene=A0A1D5NXF3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11267", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11267", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11267:SF91", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11267:SF91", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00907", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00907", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12598", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12598", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF20627", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20627", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001257807", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001257807", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5NXF3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NXF3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5NXF3-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NXF3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNIPMRDPVIPGTSMAYHPFLPHRAPDFAMSAVLGHQPPFFPALALPPNGAAALSLPGALAKPIMDQLVGAAETAIPFSSLGHQAAAHLRPLKTLEPEEEVEDDPKVHLEAKELWEQFHKRGTEMVITKSGRRMFPPFKVRCTGLDKKAKYILLMDIVAADDCRYKFHNSRWMVAGKADPEMPKRMYIHPDSPATGEQWMSKVVTFHKLKLTNNISDKHGFTILNSMHKYQPRFHIVRANDILKLPYSTFRTYVFPETEFIAVTAYQNDKITQLKIDNNPFAKGFRDTGNGRREKRKQLTLQSMRVYDERQKKENPTSDESSNEQTAFKCFAQSSCPAVPAVGTSSLKDLCPSEGDSDADSKDDPLLEASESGKISTTTATTPAPASSGAAASDDPRDKGGSPSKSHFFPSDSATSRSRERTEKAPPDSRHSPATISSSSRGGGLSGEELKSPLRDGPKVDENRLLGKEPFAPLTVQTDSTAHLSQGHLQNLGFPPALAGQQFFNPLGSGHPLLLHPGQFAMGGAFSGMAAGMGPLLATVSGASAGGSGLDSTVMATAAAQGLSGASTAALPFHLQQHVLASQGLAMSPFGSLFPYPYTYMAAAAAASSAASNSVHRHPFLNAVRPRLRYSPYPLPVPLPDGSSLLTTAMPGALAATSGETKGSALASSPGAVPLDSASDLTSRSSTLSSGSVSLSPKLGADKEAATSELQNIQRLVSGLDPKQDRSRSGSP", "length": 732, "header": "tr|A0A1D5NXF3-1|A0A1D5NXF3_CHICK Isoform 1 of T-box transcription factor 3 OS=Gallus gallus OX=9031 GN=TBX3 PE=4 SV=1 CANONICAL=A0A1D5NXF3-1" }, "isoforms": [ { "isoform_ac": "A0A1D5NXF3-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NXF3/entry#A0A1D5NXF3-1", "sequence": { "sequence": "MNIPMRDPVIPGTSMAYHPFLPHRAPDFAMSAVLGHQPPFFPALALPPNGAAALSLPGALAKPIMDQLVGAAETAIPFSSLGHQAAAHLRPLKTLEPEEEVEDDPKVHLEAKELWEQFHKRGTEMVITKSGRRMFPPFKVRCTGLDKKAKYILLMDIVAADDCRYKFHNSRWMVAGKADPEMPKRMYIHPDSPATGEQWMSKVVTFHKLKLTNNISDKHGFTILNSMHKYQPRFHIVRANDILKLPYSTFRTYVFPETEFIAVTAYQNDKITQLKIDNNPFAKGFRDTGNGRREKRKQLTLQSMRVYDERQKKENPTSDESSNEQTAFKCFAQSSCPAVPAVGTSSLKDLCPSEGDSDADSKDDPLLEASESGKISTTTATTPAPASSGAAASDDPRDKGGSPSKSHFFPSDSATSRSRERTEKAPPDSRHSPATISSSSRGGGLSGEELKSPLRDGPKVDENRLLGKEPFAPLTVQTDSTAHLSQGHLQNLGFPPALAGQQFFNPLGSGHPLLLHPGQFAMGGAFSGMAAGMGPLLATVSGASAGGSGLDSTVMATAAAQGLSGASTAALPFHLQQHVLASQGLAMSPFGSLFPYPYTYMAAAAAASSAASNSVHRHPFLNAVRPRLRYSPYPLPVPLPDGSSLLTTAMPGALAATSGETKGSALASSPGAVPLDSASDLTSRSSTLSSGSVSLSPKLGADKEAATSELQNIQRLVSGLDPKQDRSRSGSP", "length": 732, "header": "tr|A0A1D5NXF3-1|A0A1D5NXF3_CHICK Isoform 1 of T-box transcription factor 3 OS=Gallus gallus OX=9031 GN=TBX3 PE=4 SV=1 CANONICAL=A0A1D5NXF3-1" }, "locus": { "chromosome": "15", "start_pos": 12224261, "end_pos": 12214470, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010000925.1", "url": "https://www.ensembl.org/id/ENSGALT00010000925.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010000489.1", "url": "https://www.ensembl.org/id/ENSGALP00010000489.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Tbx Genes Specify Posterior Digit Identity through Shh and BMP Signaling.", "journal": "Developmental cell", "date": "2004-01", "authors": "Suzuki Takayuki, Takeuchi Jun, Koshiba-Takeuchi Kazuko, Ogura Toshihiko", "evidence": [ { "database": "RefSeq", "id": "NP_001257807", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001257807" } ], "reference": [ { "type": "PubMed", "id": "14723846", "url": "https://glygen.org/publication/PubMed/14723846" } ] } ], "pathway": [ { "id": "gga:374202", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:374202", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "B8JKS6-1", "protein_name": "T-box transcription factor TBX3a", "gene_name": "tbx3a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MRDPVIQGSSMAYHPFLPHRGPEFAMSAMLGHQPPFFPALALPPNGSLSLPGALGKPIMEQLMGAAETGLHFSSLGHQAAHLRPLKTLEPEEEVEDDPKVHLEAKELWELFHKRGTEMVITKSGRRMFPPFKVRCTGLDKKAKYILLMDIVAADDCRYKFHNSRWMVAGKADPEMPKRMYIHPDSPATGEQWMSKVVNFHKLKLTNNISDKHGFTILNSMHKYQPRFHIVRANDILKLPYSTFRTYVFPETDFIAVTAYQNDKITQLKIDHNPFAKGFRDTGNGRREKRKQLALQSMRSYEEQQKKENGTSDDSSGEQASFKCFRQASSPAVSTAGHNHLKDFCDSDEDSDEEDKDANAKEGPDSSKISTTTEDSKDQDAGLGKSVFGESDSSSGRRSEKTRADSRSPITLISSTTRSGEELKSPVREPAKTTDDCRTVSKENYMPLTVQTDGAAHLNQNHLHNFGFPPGLAGQQFFNHLGGAHPFLLHPSQFNMGGAFSNMAAGMGPILAAVSSGGVGSLDGSSLPSPSQSLTGAPMPFHLQQHVLASQGLAMSPFGGLFPYPYTYMAAAAAASSAASSSVHRHPFLSAVRPRLRYSPYSLPSVPDSTLLTTAMQPMASSGLEVKGDGMNTSPASAALDSEVTSRSSGSVSLSPKTCTEKDSSSELQSIQRLVSGLEPKPDRARSVSP", "length": 689 }, "evidence": [ { "id": "A0A1D5NXF3", "url": "https://omabrowser.org/oma/group/A0A1D5NXF3/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E1BK57-1", "protein_name": "T-box transcription factor 3", "gene_name": "TBX3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": 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beta-1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990412" }, "gene_names": [ { "name": "CTNNB1", "type": "recommended", "evidence": [ { "id": "A0A1D5NYE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYE8" } ] }, { "name": "CHBCAT", "type": "synonym", "evidence": [ { "id": "NP_990412", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990412" } ] }, { "name": "CTNNB1", "type": "synonym", "evidence": [ { "id": "NP_990412", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990412" } ] }, { "name": "beta-catenin", "type": "synonym", "evidence": [ { "id": "NP_990412", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990412" } ] } ], "protein_names": [ { "name": "Catenin beta 1", "type": "synonym", "evidence": [ { "id": "A0A1D5NYE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYE8/entry#names_and_taxonomy" } ] }, { "name": "beta catenin", "type": "synonym", "evidence": [ { "id": "NP_990412", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990412" } ] }, { "name": "catenin (cadherin-associated protein), beta 1, 88kDa", "type": "synonym", "evidence": [ { "id": "NP_990412", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990412" } ] }, { "name": "catenin beta-1", "type": "synonym", "evidence": [ { "id": "NP_990412", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990412" } ] } ], "function": [ { "annotation": "Beta-catenin may be involved in regulating adhesive properties of cells during chick gastrulation", "evidence": [ { "database": "RefSeq", "id": "NP_990412", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990412" }, { "database": "PubMed", "id": "14991726", "url": "https://glygen.org/publication/PubMed/14991726" } ] }, { "annotation": "Beta-catenin role in the cardiomyocyte differentiation during chick cardiogenesis.", "evidence": [ { "database": "RefSeq", 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Publication Status: Online-Only", "evidence": [ { "database": "RefSeq", "id": "NP_990412", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990412" }, { "database": "PubMed", "id": "27218451", "url": "https://glygen.org/publication/PubMed/27218451" } ] }, { "annotation": "We demonstrate that the balance of Ecad and Ncad is dependent upon the availability of beta-catenin proteins, and that alteration of either classical cadherin modifies the proportions of the neural crest and neuroectodermal cells that are specified", "evidence": [ { "database": "RefSeq", "id": "NP_990412", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990412" }, { "database": "PubMed", "id": "30009960", "url": "https://glygen.org/publication/PubMed/30009960" } ] }, { "annotation": "We show that b-catenin is expressed during the pre-patterning of the epithelium prior to papilla induction and second that b-catenin, Ednrb and Inhba are expressed during the induction and patterning of the conjunctival papillae. Furthermore, we identified two genes, b-catenin and Prox1, that may be involved in the induction of the underlying scleral bones", "evidence": [ { "database": "RefSeq", "id": "NP_990412", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990412" }, { "database": "PubMed", "id": "27664768", "url": "https://glygen.org/publication/PubMed/27664768" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NYE8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYE8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CTNNB1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYE8", "locus": { "chromosome": "2", "start_pos": 43378263, "end_pos": 43356655, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010016258", "url": 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"R-GGA-9958810", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9958810", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9958825", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9958825", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_990412", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990412", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5NYE8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYE8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5NYE8-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYE8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PQN0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PQN0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PQN0-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PQN0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MATQADLMELDMAMEPDRKAAVSHWQQQSYLDSGIHSGATTTAPSLSGKGNPEEEDVDTTQVLYEWEQGFSQSFTQEQVADIDGQYAMTRAQRVRAAMFPETLDEGMQIPSTQFDAAHPTNVQRLAEPSQMLKHAVVNLINYQDDAELATRAIPELTKLLNDEDQVVVNKAAVMVHQLSKKEASRHAIMRSPQMVSAIVRTMQNTNDVETARCTAGTLHNLSHHREGLLAIFKSGGIPALVKMLGSPVDSVLFYAITTLHNLLLHQEGAKMAVRLAGGLQKMVALLNKTNVKFLAITTDCLQILAYGNQESKLIILASGGPQALVNIMRTYTYEKLLWTTSRVLKVLSVCSSNKPAIVEAGGMQALGLHLTDPSQRLVQNCLWTLRNLSDAATKQEGMEGLLGTLVQLLGSDDINVVTCAAGILSNLTCNNYKNKMMVCQVGGIEALVRTVLRAGDREDITEPAICALRHLTSRHQEAEMAQNAVRLHYGLPVVVKLLHPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLLVRAHQDTQRRTSMGGTQQQFVEGVRMEEIVEGCTGALHILARDVHNRIVIRGLNTIPLFVQLLYSPIENIQRVAAGVLCELAQDKEAAEAIEAEGATAPLTELLHSRNEGVATYAAAVLFRMSEDKPQDYKKRLSVELTSSLFRTEPMAWNETADLGLDIGAQGEPLGYRPDDPSYRSFHSGGYGQDALGMDPMMEHEMGGHHPGADYPVDGLPDLGHAQDLMDGLPPGDSNQLAWFDTDL", "length": 781, "header": "tr|A0A1D5NYE8-1|A0A1D5NYE8_CHICK Isoform 1 of Catenin beta 1 OS=Gallus gallus OX=9031 GN=CTNNB1 PE=1 SV=1 CANONICAL=A0A1D5NYE8-1" }, "isoforms": [ { "isoform_ac": "A0A1D5NYE8-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYE8/entry#A0A1D5NYE8-1", "sequence": { "sequence": "MATQADLMELDMAMEPDRKAAVSHWQQQSYLDSGIHSGATTTAPSLSGKGNPEEEDVDTTQVLYEWEQGFSQSFTQEQVADIDGQYAMTRAQRVRAAMFPETLDEGMQIPSTQFDAAHPTNVQRLAEPSQMLKHAVVNLINYQDDAELATRAIPELTKLLNDEDQVVVNKAAVMVHQLSKKEASRHAIMRSPQMVSAIVRTMQNTNDVETARCTAGTLHNLSHHREGLLAIFKSGGIPALVKMLGSPVDSVLFYAITTLHNLLLHQEGAKMAVRLAGGLQKMVALLNKTNVKFLAITTDCLQILAYGNQESKLIILASGGPQALVNIMRTYTYEKLLWTTSRVLKVLSVCSSNKPAIVEAGGMQALGLHLTDPSQRLVQNCLWTLRNLSDAATKQEGMEGLLGTLVQLLGSDDINVVTCAAGILSNLTCNNYKNKMMVCQVGGIEALVRTVLRAGDREDITEPAICALRHLTSRHQEAEMAQNAVRLHYGLPVVVKLLHPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLLVRAHQDTQRRTSMGGTQQQFVEGVRMEEIVEGCTGALHILARDVHNRIVIRGLNTIPLFVQLLYSPIENIQRVAAGVLCELAQDKEAAEAIEAEGATAPLTELLHSRNEGVATYAAAVLFRMSEDKPQDYKKRLSVELTSSLFRTEPMAWNETADLGLDIGAQGEPLGYRPDDPSYRSFHSGGYGQDALGMDPMMEHEMGGHHPGADYPVDGLPDLGHAQDLMDGLPPGDSNQLAWFDTDL", "length": 781, "header": "tr|A0A1D5NYE8-1|A0A1D5NYE8_CHICK Isoform 1 of Catenin beta 1 OS=Gallus gallus OX=9031 GN=CTNNB1 PE=1 SV=1 CANONICAL=A0A1D5NYE8-1" }, "locus": { "chromosome": "2", "start_pos": 43377163, "end_pos": 43369697, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010039083.1", "url": "https://www.ensembl.org/id/ENSGALT00010039083.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022572.1", "url": "https://www.ensembl.org/id/ENSGALP00010022572.1" } ] } }, { "isoform_ac": "A0A1D5PQN0-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYE8/entry#A0A1D5PQN0-1", "sequence": { "sequence": "MATQADLMELDMAMEPDRKAAVSHWQQQSYLDSGIHSGATTTAPSLSGKGNPEEEDVDTTQVLYEWEQGFSQSFTQEQVADIDGQYAMTRAQRVRAAMFPETLDEGMQIPSTQFDAAHPTNVQRLAEPSQMLKHAVVNLINYQDDAELATRAIPELTKLLNDEDQVVVNKAAVMVHQLSKKEASRHAIMRSPQMVSAIVRTMQNTNDVETARCTAGTLHNLSHHREGLLAIFKSGGIPALVKMLGSPVDSVLFYAITTLHNLLLHQEGAKMAVRLAGGLQKMVALLNKTNVKFLAITTDCLQILAYGNQESKLIILASGGPQALVNIMRTYTYEKLLWTTSRVLKVLSVCSSNKPAIVEAGGMQALGLHLTDPSQRLVQNCLWTLRNLSDAATKQEGMEGLLGTLVQLLGSDDINVVTCAAGILSNLTCNNYKNKMMVCQVGGIEALVRTVLRAGDREDITEPAICALRHLTSRHQEAEMAQNAVRLHYGLPVVVKLLHPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLLVRAHQDTQRRTSMGGTQQQFVEGVRMEEIVEGCTGALHILARDVHNRIVIRGLNTIPLFVQLLYSPIENIQRVAAGVLCELAQDKEAAEAIEAEGATAPLTELLHSRNEGVATYAAAVLFRMSEDKPQDYKKRLSVELTSSLFRTEPMAWNETADLGLDIGAQGEPLGYRPDAVSSE", "length": 717, "header": "tr|A0A1D5PQN0-1|A0A1D5NYE8_CHICK Computationally mapped isoform of Catenin beta 1 OS=Gallus gallus OX=9031 GN=CTNNB1 PE=1 SV=1 CANONICAL=A0A1D5NYE8-1" }, "locus": { "chromosome": "2", "start_pos": 43377501, "end_pos": 43369697, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010039095.1", "url": "https://www.ensembl.org/id/ENSGALT00010039095.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022580.1", "url": "https://www.ensembl.org/id/ENSGALP00010022580.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "WNT signals control FGF-dependent limb initiation and AER induction in the chick embryo.", "journal": "Cell", "date": "2001-03-23", "authors": "Kawakami Y, Capdevila J, B\u00fcscher D, Itoh T, Rodr\u00edguez Esteban C, Izpis\u00faa Belmonte J C", "evidence": [ { "database": "RefSeq", "id": "NP_990412", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990412" } ], "reference": [ { "type": "PubMed", "id": "11290326", "url": "https://glygen.org/publication/PubMed/11290326" } ] }, { "title": "Dynamic expression of Lef/Tcf family members and beta-catenin during chick gastrulation, neurulation, and early limb development.", "journal": "Developmental dynamics : an official publication of the American Association of Anatomists", "date": "2004-03", "authors": "Schmidt Maike, Patterson Margaret, Farrell Elizabeth, M\u00fcnsterberg Andrea", "evidence": [ { "database": "RefSeq", "id": "NP_990412", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990412" } ], "reference": [ { "type": "PubMed", "id": "14991726", "url": "https://glygen.org/publication/PubMed/14991726" } ] }, { "title": "Cytoplasmic NOTCH and membrane-derived \u03b2-catenin link cell fate choice to epithelial-mesenchymal transition during myogenesis.", "journal": "eLife", "date": "2016-05-24", "authors": "Sieiro Daniel, Rios Anne C, Hirst Claire E, Marcelle Christophe", "evidence": [ { "database": "RefSeq", "id": "NP_990412", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990412" } ], "reference": [ { "type": "PubMed", "id": "27218451", "url": "https://glygen.org/publication/PubMed/27218451" } ] }, { "title": "Gene expression analysis during the induction and patterning of the conjunctival papillae in the chick embryonic eye.", "journal": "Gene expression patterns : GEP", "date": "2016-09", "authors": "Jourdeuil Karyn, Franz-Odendaal Tamara Anne", "evidence": [ { "database": "RefSeq", "id": "NP_990412", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990412" } ], "reference": [ { "type": "PubMed", "id": "27664768", "url": "https://glygen.org/publication/PubMed/27664768" } ] }, { "title": "\u03b2-Catenin stabilization promotes proliferation and increase in cardiomyocyte number in chick embryonic epicardial explant culture.", "journal": "In vitro cellular & developmental biology. Animal", "date": "2017-12", "authors": "Polley Anisha, Sen Puja, Sengupta Arunima, Chakraborty Santanu", "evidence": [ { "database": "RefSeq", "id": "NP_990412", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990412" } ], "reference": [ { "type": "PubMed", "id": "28842809", "url": "https://glygen.org/publication/PubMed/28842809" } ] }, { "title": "A catenin-dependent balance between N-cadherin and E-cadherin controls neuroectodermal cell fate choices.", "journal": "Mechanisms of development", "date": "2018-08", "authors": "Rogers Crystal D, Sorrells Lisa K, Bronner Marianne E", "evidence": [ { "database": "RefSeq", "id": "NP_990412", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990412" } ], "reference": [ { "type": "PubMed", "id": "30009960", "url": "https://glygen.org/publication/PubMed/30009960" } ] } ], "pathway": [ { "id": "gga:395964", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395964", "resource": "KEGG Pathway" }, { "id": "R-GGA-195253", "name": "", 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"https://omabrowser.org/oma/group/A0A1D5NYE8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 59, "go_terms": [ { "name": "regulation of calcium ion import", "id": "GO:0090279", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090279", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NYE8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYE8" } ], "pmid": "" }, { "name": "regulation of centriole-centriole cohesion", "id": "GO:0030997", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030997", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NYE8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYE8" } ], "pmid": "" }, { "name": "cranial skeletal system development", "id": "GO:1904888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904888", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NYE8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYE8" } ], "pmid": "" }, { "name": "synaptic vesicle clustering", "id": "GO:0097091", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097091", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NYE8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYE8" } ], "pmid": "" }, { "name": "positive regulation of odontoblast differentiation", "id": "GO:1901331", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901331", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NYE8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYE8" } ], "pmid": "" }, { "name": "negative regulation of cell population proliferation", "id": "GO:0008285", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008285", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NYE8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYE8" } ], "pmid": "" }, { "name": "negative regulation of gene expression", "id": "GO:0010629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010629", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NYE8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYE8" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NYE8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYE8" } ], "pmid": "" }, { "name": "negative regulation of canonical Wnt signaling pathway", "id": "GO:0090090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090090", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NYE8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYE8" } ], "pmid": "" }, { "name": "negative regulation of DNA-templated transcription", "id": "GO:0045892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045892", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NYE8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYE8" } ], "pmid": "" }, { "name": "cell-cell adhesion", "id": "GO:0098609", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098609", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NYE8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYE8" } ], "pmid": "" }, { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NYE8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYE8" } ], "pmid": "" }, { "name": "cellular response to growth factor stimulus", "id": "GO:0071363", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071363", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NYE8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYE8" } ], "pmid": "" }, { "name": "epidermal growth factor receptor signaling pathway", "id": "GO:0007173", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007173", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NYE8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYE8" } ], "pmid": "" }, { "name": "hindbrain development", "id": "GO:0030902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030902", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NYE8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYE8" } ], "pmid": "" }, { "name": "response to estradiol", "id": "GO:0032355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032355", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NYE8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYE8" } ], "pmid": "" }, { "name": "positive regulation of blood vessel branching", "id": "GO:1905555", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905555", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NYE8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYE8" } ], "pmid": "" }, { "name": "negative regulation of angiogenesis", "id": "GO:0016525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016525", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NYE8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYE8" } ], "pmid": "" }, { "name": "positive regulation of skeletal muscle tissue development", "id": "GO:0048643", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048643", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NYE8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYE8" } ], "pmid": "" }, { "name": "regulation of synapse assembly", "id": "GO:0051963", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051963", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NYE8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYE8" } ], "pmid": "" }, { "name": "endothelial tube morphogenesis", "id": "GO:0061154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061154", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NYE8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYE8" } ], "pmid": "" }, { "name": "positive regulation of neuron apoptotic process", "id": "GO:0043525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043525", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NYE8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYE8" } ], "pmid": "" }, { "name": "canonical Wnt signaling pathway", "id": "GO:0060070", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060070", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NYE8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYE8" } ], "pmid": "" }, { "name": "limb development", "id": "GO:0060173", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060173", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NYE8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYE8" } ], "pmid": "" }, { "name": "protein polyubiquitination", "id": "GO:0000209", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000209", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NYE8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYE8" } ], "pmid": "" }, { "name": "osteoblast differentiation", "id": "GO:0001649", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001649", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NYE8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYE8" } ], "pmid": "" }, { "name": "positive regulation of epithelial to mesenchymal transition", "id": "GO:0010718", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010718", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NYE8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYE8" } ], "pmid": "" }, { "name": "regulation of smooth muscle cell proliferation", "id": "GO:0048660", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048660", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NYE8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYE8" } ], "pmid": "" }, { "name": "response to xenobiotic stimulus", "id": "GO:0009410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009410", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NYE8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYE8" } ], "pmid": "" }, { "name": "positive regulation of homotypic cell-cell adhesion", "id": "GO:0034112", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034112", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NYE8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYE8" } ], "pmid": "" }, { "name": "protein localization to cell surface", "id": "GO:0034394", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034394", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NYE8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYE8" } ], "pmid": "" }, { "name": "negative regulation of neurogenesis", "id": "GO:0050768", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050768", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NYE8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYE8" } ], "pmid": "" }, { "name": "sympathetic ganglion development", "id": "GO:0061549", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061549", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NYE8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYE8" } ], "pmid": "" }, { "name": "positive regulation of neuroblast proliferation", "id": "GO:0002052", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002052", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NYE8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYE8" } ], "pmid": "" }, { "name": "outflow tract morphogenesis", "id": "GO:0003151", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003151", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NYE8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYE8" } ], "pmid": "" }, { "name": "hypothalamus development", "id": "GO:0021854", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021854", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NYE8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYE8" } ], "pmid": "" }, { "name": "embryonic brain development", "id": "GO:1990403", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990403", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NYE8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYE8" } ], "pmid": "" }, { "name": "adherens junction assembly", "id": "GO:0034333", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034333", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NYE8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYE8" } ], "pmid": "" }, { "name": "regulation of centromeric sister chromatid cohesion", "id": "GO:0070602", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070602", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NYE8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYE8" } ], "pmid": "" }, { "name": "neuron projection extension", "id": "GO:1990138", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990138", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NYE8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYE8" } ], "pmid": "" }, { "name": "regulation of protein localization to cell surface", "id": "GO:2000008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000008", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NYE8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYE8" } ], "pmid": "" }, { "name": "positive regulation of transcription elongation by RNA polymerase II", "id": "GO:0032968", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032968", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NYE8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYE8" } ], "pmid": "" }, { "name": "cellular response to indole-3-methanol", "id": "GO:0071681", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071681", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NYE8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYE8" } ], "pmid": "" }, { "name": "cell-cell adhesion mediated by cadherin", "id": "GO:0044331", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044331", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NYE8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYE8" } ], "pmid": "" }, { "name": "regulation of protein ubiquitination", "id": "GO:0031396", "url": 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"negative regulation of protein sumoylation", "id": "GO:0033234", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033234", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NYE8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYE8" } ], "pmid": "" }, { "name": "positive regulation of heparan sulfate proteoglycan biosynthetic process", "id": "GO:0010909", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010909", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NYE8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYE8" } ], "pmid": "" }, { "name": "embryonic skeletal limb joint morphogenesis", "id": "GO:0036023", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036023", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NYE8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYE8" } ], "pmid": "" }, { "name": "negative regulation of mitotic cell cycle, embryonic", "id": "GO:0045976", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045976", "evidence": [ { "database": 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{ "name": "Cellular Component", "total": 31, "go_terms": [ { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NYE8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYE8" } ], "pmid": "" }, { "name": "presynaptic active zone cytoplasmic component", "id": "GO:0098831", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098831", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NYE8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYE8" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NYE8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYE8" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NYE8", "url": 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"https://www.uniprot.org/uniprotkb/A0A8V0YR37-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPKTISVRVTTMDAELEFAIQPNTTGKQLFDQVVKTIGLREVWFFGLQYQDTKGFSTWLKLNKKVTAQDVRKESPLLFKFRAKFYPEDVAEELIQDITQRLFFLQVKEAILNDDIYCPPETAVLLASYAVQSKYGDFNKDVHKSGYLASDKLLPQRVLEQHKLNKDQWEERIQVWHEEHRGMIREDAVLEYLKIAQDLEMYGVNYFNIKNKKGSELWLGVDALGLNIYEQNDRLTPKIGFPWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILALCMGNHELYMRRRKPDTIEVQQMKAQAREEKHQKQMERALLENEKKKRELAEKEKEKIEREKEELMEKLKQIEEQTKKAQQELEEQTRRAMELEQERKRAQEEAEKLAKERREAEEAKEALLKASHDQQKTQEQLAAEMAELTARITQLELARQKKESEAQEWQQKAQMVQEDLEKTKEELKTAMSTPHVTEPMHAENEHDDEQDENAAEASAELRSEATIKDRSEEQRTTEAEKNERVQKHLKALSSELANARDETKKTANDMIHAENMRLGRDKYKTLRQIRQGNTKQRIDEFESM", "length": 580, "header": "tr|A0A1D5NYK7-1|A0A1D5NYK7_CHICK Isoform 1 of Moesin OS=Gallus gallus OX=9031 GN=MSN PE=1 SV=1 CANONICAL=A0A1D5NYK7-1" }, "isoforms": [ { "isoform_ac": "A0A1D5NYK7-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYK7/entry#A0A1D5NYK7-1", "sequence": { "sequence": "MPKTISVRVTTMDAELEFAIQPNTTGKQLFDQVVKTIGLREVWFFGLQYQDTKGFSTWLKLNKKVTAQDVRKESPLLFKFRAKFYPEDVAEELIQDITQRLFFLQVKEAILNDDIYCPPETAVLLASYAVQSKYGDFNKDVHKSGYLASDKLLPQRVLEQHKLNKDQWEERIQVWHEEHRGMIREDAVLEYLKIAQDLEMYGVNYFNIKNKKGSELWLGVDALGLNIYEQNDRLTPKIGFPWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILALCMGNHELYMRRRKPDTIEVQQMKAQAREEKHQKQMERALLENEKKKRELAEKEKEKIEREKEELMEKLKQIEEQTKKAQQELEEQTRRAMELEQERKRAQEEAEKLAKERREAEEAKEALLKASHDQQKTQEQLAAEMAELTARITQLELARQKKESEAQEWQQKAQMVQEDLEKTKEELKTAMSTPHVTEPMHAENEHDDEQDENAAEASAELRSEATIKDRSEEQRTTEAEKNERVQKHLKALSSELANARDETKKTANDMIHAENMRLGRDKYKTLRQIRQGNTKQRIDEFESM", "length": 580, "header": "tr|A0A1D5NYK7-1|A0A1D5NYK7_CHICK Isoform 1 of Moesin OS=Gallus gallus OX=9031 GN=MSN PE=1 SV=1 CANONICAL=A0A1D5NYK7-1" }, "locus": { "chromosome": "4", "start_pos": 141353, "end_pos": 104634, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036379.1", "url": "https://www.ensembl.org/id/ENSGALT00010036379.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021165.1", "url": "https://www.ensembl.org/id/ENSGALP00010021165.1" } ] } }, { "isoform_ac": "A0A8V0YJM5-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYK7/entry#A0A8V0YJM5-1", "sequence": { "sequence": "MPSVRVTTMDAELEFAIQPNTTGKQLFDQVVKTIGLREVWFFGLQYQDTKGFSTWLKLNKKVTAQDVRKESPLLFKFRAKFYPEDVAEELIQDITQRLFFLQVKEAILNDDIYCPPETAVLLASYAVQSKYGDFNKDVHKSGYLASDKLLPQRVLEQHKLNKDQWEERIQVPFSLLSHPLPSLTRNRAALEPLQKSDHGLIYRVILVNAGVRQQKKERHLHIPGVAWESKLVLGQI", "length": 236, "header": "tr|A0A8V0YJM5-1|A0A1D5NYK7_CHICK Computationally mapped isoform of Moesin OS=Gallus gallus OX=9031 GN=MSN PE=1 SV=1 CANONICAL=A0A1D5NYK7-1" }, "locus": { "chromosome": "4", "start_pos": 141580, "end_pos": 124425, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036339.1", "url": "https://www.ensembl.org/id/ENSGALT00010036339.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021134.1", "url": "https://www.ensembl.org/id/ENSGALP00010021134.1" } ] } }, { "isoform_ac": "A0A8V0YJQ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYK7/entry#A0A8V0YJQ0-1", "sequence": { "sequence": "MPKTVVKTIGLREVWFFGLQYQDTKGFSTWLKLNKKVTAQDVRKESPLLFKFRAKFYPEDVAEELIQDITQRLFFLQVKEAILNDDIYCPPETAVLLASYAVQSKYGDFNKDVHKSGYLASDKLLPQRVLEQHKLNKDQWEERIQVWHEEHRGMIREDAVLEYLKIAQDLEMYGVNYFNIKNKKGSELWLGVDALGLNIYEQNDRLTPKIGFPWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILALCMGNHELYMRRRKPDTIEVQQMKAQAREEKHQKQMERALLENEKKKRELAEKEKEKIEREKEELMEKLKQIEEQTKKAQQELEEQTRRAMELEQERKRAQEEAEKLAKERREAEEAKEALLKASHDQQKTQEQLAAEMAELTARITQLELARQKKESEAQEWQQKAQMVQEDLEKTKEELKTAMSTPHVTEPMHAENEHDDEQDENAAEASAELRSEATIKDRSEEQRTTEAEKNERVQKHLKALSSELANARDETKKTANDMIHAENMRLGRDKYKTLRQIRQGNTKQRIDEFESM", "length": 552, "header": "tr|A0A8V0YJQ0-1|A0A8V0YJQ0_CHICK Computationally mapped isoform of Moesin OS=Gallus gallus OX=9031 GN=MSN PE=1 SV=1 CANONICAL=A0A1D5NYK7-1" }, "locus": { "chromosome": "4", "start_pos": 141353, "end_pos": 104634, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036374.1", "url": "https://www.ensembl.org/id/ENSGALT00010036374.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021161.1", "url": "https://www.ensembl.org/id/ENSGALP00010021161.1" } ] } }, { "isoform_ac": "A0A8V0YR32-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYK7/entry#A0A8V0YR32-1", "sequence": { "sequence": "MKELPNRICQVVKTIGLREVWFFGLQYQDTKGFSTWLKLNKKVTAQDVRKESPLLFKFRAKFYPEDVAEELIQDITQRLFFLQVKEAILNDDIYCPPETAVLLASYAVQSKYGDFNKDVHKSGYLASDKLLPQRVLEQHKLNKDQWEERIQVWHEEHRGMIREDAVLEYLKIAQDLEMYGVNYFNIKNKKGSELWLGVDALGLNIYEQNDRLTPKIGFPWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILALCMGNHELYMRRRKPDTIEVQQMKAQAREEKHQKQMERALLENEKKKRELAEKEKEKIEREKEELMEKLKQIEEQTKKAQQELEEQTRRAMELEQERKRAQEEAEKLAKERREAEEAKEALLKASHDQQKTQEQLAAEMAELTARITQLELARQKKESEAQEWQQKAQMVQEDLEKTKEELKTAMSTPHVTEPMHAENEHDDEQDENAAEASAELRSEATIKDRSEEQRTTEAEKNERVQKHLKALSSELANARDETKKTANDMIHAENMRLGRDKYKTLRQIRQGNTKQRIDEFESM", "length": 558, "header": "tr|A0A8V0YR32-1|A0A1D5NYK7_CHICK Computationally mapped isoform of Moesin OS=Gallus gallus OX=9031 GN=MSN PE=1 SV=1 CANONICAL=A0A1D5NYK7-1" }, "locus": { "chromosome": "4", "start_pos": 141353, "end_pos": 125749, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036364.1", "url": "https://www.ensembl.org/id/ENSGALT00010036364.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021152.1", "url": "https://www.ensembl.org/id/ENSGALP00010021152.1" } ] } }, { "isoform_ac": "A0A8V0YR37-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYK7/entry#A0A8V0YR37-1", "sequence": { "sequence": "MSISVRVTTMDAELEFAIQPNTTGKQLFDQVVKTIGLREVWFFGLQYQDTKGFSTWLKLNKKVTAQDVRKESPLLFKFRAKFYPEDVAEELIQDITQRLFFLQVKEAILNDDIYCPPETAVLLASYAVQSKYGDFNKDVHKSGYLASDKLLPQRVLEQHKLNKDQWEERIQVWHEEHRGMIREDAVLEYLKIAQDLEMYGVNYFNIKNKKGSELWLGVDALGLNIYEQNDRLTPKIGFPWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILALCMGNHELYMRRRKPDTIEVQQMKAQAREEKHQKQMERALLENEKKKRELAEKEKEKIEREKEELMEKLKQIEEQTKKAQQELEEQTRRAMELEQERKRAQEEAEKLAKERREAEEAKEALLKASHDQQKTQEQLAAEMAELTARITQLELARQKKESEAQEWQQKAQMVQEDLEKTKEELKTAMSTPHVTEPMHAENEHDDEQDENAAEASAELRSEATIKDRSEEQRTTEAEKNERVQKHLKALSSELANARDETKKTANDMIHAENMRLGRDKYKTLRQIRQGNTKQRIDEFESM", "length": 578, "header": "tr|A0A8V0YR37-1|A0A1D5NYK7_CHICK Computationally mapped isoform of Moesin OS=Gallus gallus OX=9031 GN=MSN PE=1 SV=1 CANONICAL=A0A1D5NYK7-1" }, "locus": { "chromosome": "4", "start_pos": 141353, "end_pos": 118548, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036370.1", "url": "https://www.ensembl.org/id/ENSGALT00010036370.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021157.1", "url": "https://www.ensembl.org/id/ENSGALP00010021157.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Activation of ezrin/radixin/moesin mediates attractive growth cone guidance through regulation of growth cone actin and adhesion receptors.", "journal": "The Journal of neuroscience : the official journal of the Society for Neuroscience", "date": "2012-01-04", "authors": "Marsick Bonnie M, San Miguel-Ruiz Jose E, Letourneau Paul C", "evidence": [ { "database": "RefSeq", "id": "NP_001376296", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376296" } ], "reference": [ { "type": "PubMed", "id": "22219290", "url": "https://glygen.org/publication/PubMed/22219290" } ] } ], "pathway": [ { "id": "R-GGA-437239", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-437239", "resource": "Reactome", "description": "Recycling pathway of L1" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2N5H4-1", "protein_name": "Moesin", "gene_name": "Msn", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MPKTISVRVTTMDAELEFAIQPNTTGKQLFDQVVKTIGLREVWFFGLQYQDTKAFSTWLKLNKKVTAQDVRKESPLLFKFRAKFYPEDVSEELIQDITQRLFFLQVKEGILNDDIYCPPETAVLLASYAVQSKYGDFNKEVHKSGYLAGDKLLPQRVLEQHKLNKDQWEERIQVWHEEHRGMLREDAVLEYLKIAQDLEMYGVNYFSIKNKKGSELWLGVDALGLNIYEQNDRLTPKIGFPWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILALCMGNHELYMRRRKPDTIEVQQMKAQAREEKHQKQMERALLENEKKKRELAEKEKEKIEREKEELMEKLKQIEEQTKKAQQELEEQTRRALELEQERKRAQSEAEKLAKERQEAEEAKEALLQASRDQKKTQEQLASEMAELTSRISQLEMARKKKESEAVEWQQKAQMVQEDLEKTRAELKTAMSTPHVAEPAENEQDEQDENGAEASAELRADAMAKDRSEEERTTEAEKNERVQKHLKALTSELANARDESKKTANDMIHAENMRLGRDKYKTLRQIRQGNTKQRIDEFESM", "length": 577 }, "evidence": [ { "id": "A0A1D5NYK7", "url": "https://omabrowser.org/oma/group/A0A1D5NYK7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8W4FGG7-1", "protein_name": "Moesin", "gene_name": "MSN", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MQGCRINVRVTTMDAELEFAIQPNTTGKQLFDQVVKTIGLREVWFFGLQYQDTKGFSTWLKLNKKVTAQDVRKESPLLFKFRAKFYPEDVSEELIQDITQRLFFLQVKEGILNDDIYCPPETAVLLASYAVQSKYGDFNKEVHKSGYLAGDKLLPQRVLEQHKLNKDQWEERIQVWHEEHRGMLREDAVLEYLKIAQDLEMYGVNYFSIKNKKGSELWLGVDALGLNIYEQNDRLTPKIGFPWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILALCMGNHELYMRRRKPDTIEVQQMKAQAREEKHQKQMERALLENEKKKREMAEKEKEKIEREKEELMERLKQIEEQTKKAQQELEEQTRRALELEQERKRAQSEAEKLAKERQEAEEAKEALLKASRDQKKTQEQLALEMAELTARISQLEMARQKKESEAAEWQQKAQMVQEDLEKTRAELKTAMSTPHVAEPAENDQDEQDENGAEASADLRADAMAKDRSEEERTTEAEKNERVQKHLKALTSELANARDESKKTANDMIHAENMRLGRDKYKTLRQIRQGNTKQRIDEFESM", "length": 578 }, "evidence": [ { "id": "A0A1D5NYK7", "url": "https://omabrowser.org/oma/group/A0A1D5NYK7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P26038-1", "protein_name": "Moesin", "gene_name": "MSN", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPKTISVRVTTMDAELEFAIQPNTTGKQLFDQVVKTIGLREVWFFGLQYQDTKGFSTWLKLNKKVTAQDVRKESPLLFKFRAKFYPEDVSEELIQDITQRLFFLQVKEGILNDDIYCPPETAVLLASYAVQSKYGDFNKEVHKSGYLAGDKLLPQRVLEQHKLNKDQWEERIQVWHEEHRGMLREDAVLEYLKIAQDLEMYGVNYFSIKNKKGSELWLGVDALGLNIYEQNDRLTPKIGFPWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILALCMGNHELYMRRRKPDTIEVQQMKAQAREEKHQKQMERAMLENEKKKREMAEKEKEKIEREKEELMERLKQIEEQTKKAQQELEEQTRRALELEQERKRAQSEAEKLAKERQEAEEAKEALLQASRDQKKTQEQLALEMAELTARISQLEMARQKKESEAVEWQQKAQMVQEDLEKTRAELKTAMSTPHVAEPAENEQDEQDENGAEASADLRADAMAKDRSEEERTTEAEKNERVQKHLKALTSELANARDESKKTANDMIHAENMRLGRDKYKTLRQIRQGNTKQRIDEFESM", "length": 577 }, "evidence": [ { "id": "A0A1D5NYK7", "url": "https://omabrowser.org/oma/group/A0A1D5NYK7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P26041-1", "protein_name": "Moesin", "gene_name": "Msn", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKTISVRVTTMDAELEFAIQPNTTGKQLFDQVVKTIGLREVWFFGLQYQDTKAFSTWLKLNKKVTAQDVRKESPLLFKFRAKFYPEDVSEELIQDITQRLFFLQVKEGILNDDIYCPPETAVLLASYAVQSKYGDFNKEVHKSGYLAGDKLLPQRVLEQHKLNKDQWEERIQVWHEEHRGMLREDAVLEYLKIAQDLEMYGVNYFSIKNKKGSELWLGVDALGLNIYEQNDRLTPKIGFPWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILALCMGNHELYMRRRKPDTIEVQQMKAQAREEKHQKQMERALLENEKKKRELAEKEKEKIEREKEELMEKLKQIEEQTKKAQQELEEQTRRALELEQERKRAQSEAEKLAKERQEAEEAKEALLQASRDQKKTQEQLASEMAELTARISQLEMARKKKESEAVEWQQKAQMVQEDLEKTRAELKTAMSTPHVAEPAENEHDEQDENGAEASAELRADAMAKDRSEEERTTEAEKNERVQKHLKALTSELANARDESKKTANDMIHAENMRLGRDKYKTLRQIRQGNTKQRIDEFESM", "length": 577 }, "evidence": [ { "id": "A0A1D5NYK7", "url": "https://omabrowser.org/oma/group/A0A1D5NYK7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q2HJ49-1", "protein_name": "Moesin", "gene_name": "MSN", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPKTINVRVTTMDAELEFAIQPNTTGKQLFDQVVKTIGLREIWFFGLQYQDTKGFFTWLKLNKKVTAQDVRKESPLLFKFRAKFYPEDVSEELIQDITQRLFFLQVKEDILNDDIYCPPETAVLLASYAVQSKYGDFNKEVHKSGYLAGDRLLPQRVLEQHKLNKDQWEERIQVWHEEHRGMLREDAVLEYLKIAQDLEMYGVNYFSIKNKKGSELWLGVDALGLNIYEQNDRLTPKIGFPWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILALCMGNHELYMRRRKPDTIEVQQMKAQAREEKHQKQMERALLENEKKKREMAEKEKEKIEREKEELMERLKQIEEQTKKAQQELEEQTRRALELEQERKRAQSEAEKLAKERQEAEEAKEALLQASQDQKKTQEQLALEMAELTARISQLEMARQKKESEAVEWQQKAQMVQEDLEKTRAELKTAMSTPHVAEPAENEQDEQDENGAEASAELRADAMAKDRSEEERTTEAEKNERVQKHLKALTSELANARDESKKTANDMIHAENMRLGRDKYKTLRQIRQGNTKQRIDEFESM", "length": 577 }, "evidence": [ { "id": "A0A1D5NYK7", "url": "https://omabrowser.org/oma/group/A0A1D5NYK7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 16, "go_terms": [ { "name": "positive regulation of protein localization to early endosome", "id": "GO:1902966", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902966", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NYK7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYK7" } ], "pmid": "" }, { "name": "membrane to membrane docking", "id": "GO:0022614", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022614", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NYK7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYK7" } ], "pmid": "" }, { "name": "establishment of endothelial barrier", "id": "GO:0061028", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061028", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NYK7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYK7" } ], "pmid": "" }, { "name": "regulation of organelle assembly", "id": "GO:1902115", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902115", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NYK7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYK7" } ], "pmid": "" }, { "name": "positive regulation of gene 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"Protein Classification" ] }, { "id": "IPR001711", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001711", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014815", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014815", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016280", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016280", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017946", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017946", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028400", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028400", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035892", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035892", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037862", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037862", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042531", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042531", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR053945", "url": "https://www.ebi.ac.uk/interpro/entry/IPR053945", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:427687", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427687", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PIVFKKX", "url": "https://omabrowser.org/oma/group/PIVFKKX/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5NZL7", "url": "https://www.orthodb.org/?gene=A0A1D5NZL7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YZV4", "url": "https://www.orthodb.org/?gene=A0A8V0YZV4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z5W2", "url": "https://www.orthodb.org/?gene=A0A8V0Z5W2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZDD4", "url": "https://www.orthodb.org/?gene=A0A8V0ZDD4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NLL3", "url": "https://www.orthodb.org/?gene=F1NLL3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10336", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10336", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10336:SF12", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10336:SF12", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00387", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00387", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00388", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00388", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08703", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08703", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17787", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17787", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22631", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22631", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-112043", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-112043", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-1855204", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1855204", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-399997", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-399997", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-4086398", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4086398", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-416476", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-416476", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-418217", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-418217", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-434316", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-434316", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-500657", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-500657", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_025005026", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025005026", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "33179", "url": "https://www.rhea-db.org/rhea/33179", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "43484", "url": "https://www.rhea-db.org/rhea/43484", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A1D5NZL7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZL7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5NZL7-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZL7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YZV4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZV4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YZV4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZV4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5W2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5W2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5W2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5W2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDD4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDD4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDD4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDD4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NLL3", "url": "https://www.uniprot.org/uniprotkb/F1NLL3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NLL3-1", "url": "https://www.uniprot.org/uniprotkb/F1NLL3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAGAQPGVHALQLKPVCVSDTLKKGIKFVKWDDDSTVVTPIILRTDPQGFFFYWTDQNKETELLDISLVKDARCGKHARAPKDPKLRELLDAGNVGSRLENRMITVVYGPDLVNISYLNLVAFQEDIAKEWSDEVFSLATNLLAQNMSRDAFLEKAYTKLKLQVTPEGRIPLKNIYRLFSADRKRVETALEACNLPSSRNDSIPQDDFTPDVYRVFLNNLCPRPEIDHIFSEFGAKSKPYLTVDQMMEFINLKQRDPRLNEILYPPLKQEQVQQLIEKYEPNSNLAKKGQISVDGFMRYLSGEENGVVPPEKLDLNEDMSQPLSHYFINSSHNTYLTAGQLAGNSSVEMYRQVLLSGCRCVELDCWKGRTAEEEPVITHGFTMTTEISFKEVIEAIAECAFKTSPFPILLSFENHVDSPKQQAKMAEYCRLIFGDALLMDPLEKYPLEPGVPLPSPMDLMYKILVKNKKKSHKSADGSAKKKLSEQASNTCSDTSSMFEPSSPGAGEAEIESDDDDDYDDDCKKSSMDEGTAGSEAMATEEMSNLVNYIQPVKFESFEVSKKRNKSFEMSSFVETKGLEQLTKSPVEFVEYNKMQLSRIYPKGTRVDSSNYMPQVFWNAGCQMVALNFQTVDLSMQINMGMYEYNGKSGYRLKPEFMRRPDKHFDPFTESIVDGIVANTLSVKIISGQFLSDKKVGTYVEVDMFGLPVDTRRKALKTKTSQGNAVNPVWEEETIVFKKVVLPTLACLRLAVYEEGGKFIGHRILPVSAIRPGYHYICLRNERNQPLTLPALFVYIEVKDYVPDTFADVIEALSNPIRYVNLMEQRAKQLAALTLEDEEEVKKEVDHGDAPSEANSEPRPTPAENGVNHTASLTSKPTTQVVHSQPTPGLVKAPAKTEDLIQSVLTEVEAQTIEELKQQKSFVKLQKKHYKEMKDLVKRHHKKTTDLIKEHTAKYNEIQNDYLRRRAVLEKTAKRDSKKRSETGSPDHGSSTIEQELASLDSEMTQKLVELKEKQQQQLLNLRQEQYYSEKYQKREHIKLLIQKLTDVAEECQNSQLKKLKETCEKEKKELKKKMDKKRQEKITEAKSKDKNQMEEEKTEMIRSYIQEVVQYIKRLEDAQSKRQEKLIEKHKEIRQQILDEKPKLQVELDQEYQDKFKRLPLEILEFVQEAMKGKISEDGDHSSAPSSLASDSGKSNHKPLQSEEELEEDNSEKVFDTTF", "length": 1219, "header": "tr|A0A1D5NZL7-1|A0A1D5NZL7_CHICK Isoform 1 of 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase OS=Gallus gallus OX=9031 GN=PLCB1 PE=1 SV=1 CANONICAL=A0A1D5NZL7-1" }, "isoforms": [ { "isoform_ac": "A0A1D5NZL7-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZL7/entry#A0A1D5NZL7-1", "sequence": { "sequence": "MAGAQPGVHALQLKPVCVSDTLKKGIKFVKWDDDSTVVTPIILRTDPQGFFFYWTDQNKETELLDISLVKDARCGKHARAPKDPKLRELLDAGNVGSRLENRMITVVYGPDLVNISYLNLVAFQEDIAKEWSDEVFSLATNLLAQNMSRDAFLEKAYTKLKLQVTPEGRIPLKNIYRLFSADRKRVETALEACNLPSSRNDSIPQDDFTPDVYRVFLNNLCPRPEIDHIFSEFGAKSKPYLTVDQMMEFINLKQRDPRLNEILYPPLKQEQVQQLIEKYEPNSNLAKKGQISVDGFMRYLSGEENGVVPPEKLDLNEDMSQPLSHYFINSSHNTYLTAGQLAGNSSVEMYRQVLLSGCRCVELDCWKGRTAEEEPVITHGFTMTTEISFKEVIEAIAECAFKTSPFPILLSFENHVDSPKQQAKMAEYCRLIFGDALLMDPLEKYPLEPGVPLPSPMDLMYKILVKNKKKSHKSADGSAKKKLSEQASNTCSDTSSMFEPSSPGAGEAEIESDDDDDYDDDCKKSSMDEGTAGSEAMATEEMSNLVNYIQPVKFESFEVSKKRNKSFEMSSFVETKGLEQLTKSPVEFVEYNKMQLSRIYPKGTRVDSSNYMPQVFWNAGCQMVALNFQTVDLSMQINMGMYEYNGKSGYRLKPEFMRRPDKHFDPFTESIVDGIVANTLSVKIISGQFLSDKKVGTYVEVDMFGLPVDTRRKALKTKTSQGNAVNPVWEEETIVFKKVVLPTLACLRLAVYEEGGKFIGHRILPVSAIRPGYHYICLRNERNQPLTLPALFVYIEVKDYVPDTFADVIEALSNPIRYVNLMEQRAKQLAALTLEDEEEVKKEVDHGDAPSEANSEPRPTPAENGVNHTASLTSKPTTQVVHSQPTPGLVKAPAKTEDLIQSVLTEVEAQTIEELKQQKSFVKLQKKHYKEMKDLVKRHHKKTTDLIKEHTAKYNEIQNDYLRRRAVLEKTAKRDSKKRSETGSPDHGSSTIEQELASLDSEMTQKLVELKEKQQQQLLNLRQEQYYSEKYQKREHIKLLIQKLTDVAEECQNSQLKKLKETCEKEKKELKKKMDKKRQEKITEAKSKDKNQMEEEKTEMIRSYIQEVVQYIKRLEDAQSKRQEKLIEKHKEIRQQILDEKPKLQVELDQEYQDKFKRLPLEILEFVQEAMKGKISEDGDHSSAPSSLASDSGKSNHKPLQSEEELEEDNSEKVFDTTF", "length": 1219, "header": "tr|A0A1D5NZL7-1|A0A1D5NZL7_CHICK Isoform 1 of 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase OS=Gallus gallus OX=9031 GN=PLCB1 PE=1 SV=1 CANONICAL=A0A1D5NZL7-1" }, "locus": { "chromosome": "3", "start_pos": 14267228, "end_pos": 13895622, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044603.1", "url": "https://www.ensembl.org/id/ENSGALT00010044603.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026553.1", "url": "https://www.ensembl.org/id/ENSGALP00010026553.1" } ] } }, { "isoform_ac": "A0A8V0YZV4-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZL7/entry#A0A8V0YZV4-1", "sequence": { "sequence": "MAGAQPGVHALQLKPVCVSDTLKKGIKFVKWDDDSTVVTPIILRTDPQGFFFYWTDQNKETELLDISLVKDARCGKHARAPKDPKLRELLDAGNVGSRLENRMITVVYGPDLVNISYLNLVAFQEDIAKEWSDEVFSLATNLLAQNMSRDAFLEKAYTKLKLQVTPEGRIPLKNIYRLFSADRKRVETALEACNLPSSRNDSIPQDDFTPDVYRVFLNNLCPRPEIDHIFSEFGAKSKPYLTVDQMMEFINLKQRDPRLNEILYPPLKQEQVQQLIEKYEPNSNLAKKGQISVDGFMRYLSGEENGVVPPEKLDLNEDMSQPLSHYFINSSHNTYLTAGQLAGNSSVEMYRQVLLSGCRCVELDCWKGRTAEEEPVITHGFTMTTEISFKEVIEAIAECAFKTSPFPILLSFENHVDSPKQQAKMAEYCRLIFGDALLMDPLEKYPLEPGVPLPSPMDLMYKILVKNKKKSHKSADGSAKKKLSEQASNTCSDTSSMFEPSSPGAGEAEIESDDDDDYDDDCKKSSMDEGTAGSEAMATEEMSNLVNYIQPVKFESFEVSKKRNKSFEMSSFVETKGLEQLTKSPVEFVEYNKMQLSRIYPKGTRVDSSNYMPQVFWNAGCQMVALNFQTVDLSMQINMGMYEYNGKSGYRLKPEFMRRPDKHFDPFTESIVDGIVANTLSVKIISGQFLSDKKVGTYVEVDMFGLPVDTRRKALKTKTSQGNAVNPVWEEETIVFKKVVLPTLACLRLAVYEEGGKFIGHRILPVSAIRPGYHYICLRNERNQPLTLPALFVYIEVKDYVPDTFADVIEALSNPIRYVNLMEQRAKQLAALTLEDEEEVKKEVDHGDAPSEANSEPRPTPAENGVNHTASLTSKPTTQVVHSQPTPGLVKAPAKTEDLIQSVLTEVEAQTIEELKQQKSFVKLQKKHYKEMKDLVKRHHKKTTDLIKEHTAKYNEIQNDYLRRRAVLEKTAKRDSKKRSETGSPDHGSSTIEQELASLDSEMTQKLVELKEKQQQQLLNLRQEQYYSEKYQKREHIKLLIQKLTDVAEECQNSQLKKLKETCEKEKKELKKKMDKKRQEKITEAKSKDKNQMEEEKTEMIRSYIQEVVQYIKRLEDAQSKRQEKLIEKHKEIRQQILDEKPKVFHANFTESMALGMTAV", "length": 1160, "header": "tr|A0A8V0YZV4-1|A0A1D5NZL7_CHICK Computationally mapped isoform of 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase OS=Gallus gallus OX=9031 GN=PLCB1 PE=1 SV=1 CANONICAL=A0A1D5NZL7-1" }, "locus": { "chromosome": "3", "start_pos": 14267228, "end_pos": 13917664, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044590.1", "url": "https://www.ensembl.org/id/ENSGALT00010044590.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026543.1", "url": "https://www.ensembl.org/id/ENSGALP00010026543.1" } ] } }, { "isoform_ac": "A0A8V0Z5W2-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZL7/entry#A0A8V0Z5W2-1", "sequence": { "sequence": "MAGAQPGVHALQLKPVCVSDTLKKGIKFVKWDDDSTVVTPIILRTDPQGFFFYWTDQNKETELLDISLVKDARCGKHARAPKDPKLRELLDAGNVGSRLENRMITVVYGPDLVNISYLNLVAFQEDIAKEWSDEVFSLATNLLAQNMSRDAFLEKAYTKLKLQVTPEGRIPLKNIYRLFSADRKRVETALEACNLPSSRNDSIPQDDFTPDVYRVFLNNLCPRPEIDHIFSEFGAKSKPYLTVDQMMEFINLKQRDPRLNEILYPPLKQEQVQQLIEKYEPNSNLAKKGQISVDGFMRYLSGEENGVVPPEKLDLNEDMSQPLSHYFINSSHNTYLTAGQLAGNSSVEMYRQVLLSGCRCVELDCWKGRTAEEEPVITHGFTMTTEISFKEVIEAIAECAFKTSPFPILLSFENHVDSPKQQAKMAEYCRLIFGDALLMDPLEKYPLEPGVPLPSPMDLMYKILVKNKKKSHKSADGSAKKKLSEQASNTCSDTSSMFEPSSPGAGEAEIESDDDDDYDDDCKKSSMDEGTAGSEAMATEEMSNLVNYIQPVKFESFEVSKKRNKSFEMSSFVETKGLEQLTKSPVEFVEYNKMQLSRIYPKGTRVDSSNYMPQVFWNAGCQMVALNFQTVDLSMQINMGMYEYNGKSGYRLKPEFMRRPDKHFDPFTESIVDGIVANTLSVKIISGQFLSDKKVGTYVEVDMFGLPVDTRRKALKTKTSQGNAVNPVWEEETIVFKKVVLPTLACLRLAVYEEGGKFIGHRILPVSAIRPGYHYICLRNERNQPLTLPALFVYIEVKDYVPDTFADVIEALSNPIRYVNLMEQRAKQLAALTLEDEEEVKKEVDHGDAPSEANSEPRPTPAENGVNHTASLTSKPTTQVVHSQPTPGLVKAPAKTEDLIQSVLTEVEAQTIEELKQQKSFVKLQKKHYKEMKDLVKRHHKKTTDLIKEHTAKYNEIQNDYLRRRAVLEKTAKRDSKKRSETGSPDHGSSTIEQELASLDSEMTQKLVELKEKQQQQLLNLRQEQYYSEKYQKREHIKLLIQKLTDVAEECQNSQLKKLKETCEKEKKELKKKMDKKRQEKITEAKSKDKNQMEEEKTEMIRSYIQEVVQYIKRLEDAQSKRQEKLIEKHKEIRQQILDEKPKMWYLHTLF", "length": 1151, "header": "tr|A0A8V0Z5W2-1|A0A1D5NZL7_CHICK Computationally mapped isoform of 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase OS=Gallus gallus OX=9031 GN=PLCB1 PE=1 SV=1 CANONICAL=A0A1D5NZL7-1" }, "locus": { "chromosome": "3", "start_pos": 14267228, "end_pos": 13955830, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044577.1", "url": "https://www.ensembl.org/id/ENSGALT00010044577.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026534.1", "url": "https://www.ensembl.org/id/ENSGALP00010026534.1" } ] } }, { "isoform_ac": "A0A8V0ZDD4-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZL7/entry#A0A8V0ZDD4-1", "sequence": { "sequence": "MAGAQPGVHALQLKPVCVSDTLKKGIKFVKWDDDSTVVTPIILRTDPQGFFFYWTDQNKETELLDISLVKDARCGKHARAPKDPKLRELLDAGNVGSRLENRMITVVYGPDLVNISYLNLVAFQEDIAKEWSDEVFSLATNLLAQNMSRDAFLEKAYTKLKLQVTPEGRIPLKNIYRLFSADRKRVETALEACNLPSSRNDSIPQDDFTPDVYRVFLNNLCPRPEIDHIFSEFGAKSKPYLTVDQMMEFINLKQRDPRLNEILYPPLKQEQVQQLIEKYEPNSNLAKKGQISVDGFMRYLSGEENGVVPPEKLDLNEDMSQPLSHYFINSSHNTYLTAGQLAGNSSVEMYRQVLLSGCRCVELDCWKGRTAEEEPVITHGFTMTTEISFKEVIEAIAECAFKTSPFPILLSFENHVDSPKQQAKMAEYCRLIFGDALLMDPLEKYPLEPGVPLPSPMDLMYKILVKNKKKSHKSADGSAKKKLSEQASNTCSDTSSMFEPSSPGAGEAEIESDDDDDYDDDCKKSSMDEGTAGSEAMATEEMSNLVNYIQPVKFESFEVSKKRNKSFEMSSFVETKGLEQLTKSPVEFVEYNKMQLSRIYPKGTRVDSSNYMPQVFWNAGCQMVALNFQTVDLSMQINMGMYEYNGKSGYRLKPEFMRRPDKHFDPFTESIVDGIVANTLSVKIISGQFLSDKKVGTYVEVDMFGLPVDTRRKALKTKTSQGNAVNPVWEEETIVFKKVVLPTLACLRLAVYEEGGKFIGHRILPVSAIRPGYHYICLRNERNQPLTLPALFVYIEVKDYVPDTFADVIEALSNPIRYVNLMEQRAKQLAALTLEDEEEVKKEVDHGDAPSEANSEPRPTPAENGVNHTASLTSKPTTQVVHSQPTPGLVKAPAKTEDLIQSVLTEVEAQTIEELKQQKSFVKLQKKHYKEMKDLVKRHHKKTTDLIKEHTAKYNEIQNDYLRRRAVLEKTAKRDSKKRSETGSPDHGSSTIEQELASLDSEMTQKLVELKEKQQQQLLNLRQEQYYSEKYQKREHIKLLIQKLTDVAEECQNSQLKKLKETCEKEKKELKKKMDKKRQEKITEAKSKDKNQMEEEKTEMIRSYIQEVVQYIKRLEDAQSKRQEKLIEKHKEIRQQILDEKPKV", "length": 1144, "header": "tr|A0A8V0ZDD4-1|A0A1D5NZL7_CHICK Computationally mapped isoform of 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase OS=Gallus gallus OX=9031 GN=PLCB1 PE=1 SV=1 CANONICAL=A0A1D5NZL7-1" }, "locus": { "chromosome": "3", "start_pos": 14267228, "end_pos": 13932097, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044582.1", "url": "https://www.ensembl.org/id/ENSGALT00010044582.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026538.1", "url": "https://www.ensembl.org/id/ENSGALP00010026538.1" } ] } }, { "isoform_ac": "F1NLL3-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZL7/entry#F1NLL3-1", "sequence": { "sequence": "MAGAQPGVHALQLKPVCVSDTLKKGIKFVKWDDDSTVVTPIILRTDPQGFFFYWTDQNKETELLDISLVKDARCGKHARAPKDPKLRELLDAGNVGSRLENRMITVVYGPDLVNISYLNLVAFQEDIAKEWSDEVFSLATNLLAQNMSRDAFLEKAYTKLKLQVTPEGRIPLKNIYRLFSADRKRVETALEACNLPSSRNDSIPQDDFTPDVYRVFLNNLCPRPEIDHIFSEFGAKSKPYLTVDQMMEFINLKQRDPRLNEILYPPLKQEQVQQLIEKYEPNSNLAKKGQISVDGFMRYLSGEENGVVPPEKLDLNEDMSQPLSHYFINSSHNTYLTAGQLAGNSSVEMYRQVLLSGCRCVELDCWKGRTAEEEPVITHGFTMTTEISFKEVIEAIAECAFKTSPFPILLSFENHVDSPKQQAKMAEYCRLIFGDALLMDPLEKYPLEPGVPLPSPMDLMYKILVKNKKKSHKSADGSAKKKLSEQASNTCSDTSSMFEPSSPGAGEAEIESDDDDDYDDDCKKSSMDEGTAGSEAMATEEMSNLVNYIQPVKFESFEVSKKRNKSFEMSSFVETKGLEQLTKSPVEFVEYNKMQLSRIYPKGTRVDSSNYMPQVFWNAGCQMVALNFQTVDLSMQINMGMYEYNGKSGYRLKPEFMRRPDKHFDPFTESIVDGIVANTLSVKIISGQFLSDKKVGTYVEVDMFGLPVDTRRKALKTKTSQGNAVNPVWEEETIVFKKVVLPTLACLRLAVYEEGGKFIGHRILPVSAIRPGYHYICLRNERNQPLTLPALFVYIEVKDYVPDTFADVIEALSNPIRYVNLMEQRAKQLAALTLEDEEEVKKEVDHGDAPSEANSEPRPTPAENGVNHTASLTSKPTTQVVHSQPTPGLVKAPAKTEDLIQSVLTEVEAQTIEELKQQKSFVKLQKKHYKEMKDLVKRHHKKTTDLIKEHTAKYNEIQNDYLRRRAVLEKTAKRDSKKRSETGSPDHGSSTIEQELASLDSEMTQKLVELKEKQQQQLLNLRQEQYYSEKYQKREHIKLLIQKLTDVAEECQNSQLKKLKETCEKEKKELKKKMDKKRQEKITEAKSKDKNQMEEEKTEMIRSYIQEVVQYIKRLEDAQSKRQEKLIEKHKEIRQQILDEKPKSIEEQEVEEKQK", "length": 1155, "header": "tr|F1NLL3-1|A0A1D5NZL7_CHICK Computationally mapped isoform of 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase OS=Gallus gallus OX=9031 GN=PLCB1 PE=1 SV=3 CANONICAL=A0A1D5NZL7-1" }, "locus": { "chromosome": "3", "start_pos": 14267228, "end_pos": 13917188, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044597.1", "url": "https://www.ensembl.org/id/ENSGALT00010044597.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026548.1", "url": "https://www.ensembl.org/id/ENSGALP00010026548.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 860, "start_aa": "Thr", "end_pos": 860, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr860", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 886, "start_aa": "Thr", "end_pos": 886, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr886", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:427687", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427687", "resource": "KEGG Pathway" }, { "id": "R-GGA-112043", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-112043", "resource": "Reactome", "description": "PLC beta mediated events" }, { "id": "R-GGA-1855204", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1855204", "resource": "Reactome", "description": "Synthesis of IP3 and IP4 in the cytosol" }, { "id": "R-GGA-399997", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-399997", "resource": "Reactome", "description": "Acetylcholine regulates insulin secretion" }, { "id": "R-GGA-4086398", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4086398", "resource": "Reactome", "description": "Ca2+ pathway" }, { "id": "R-GGA-416476", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-416476", "resource": "Reactome", "description": "G alpha (q) signalling events" }, { "id": "R-GGA-418217", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-418217", "resource": "Reactome", "description": "G beta:gamma signalling through PLC beta" }, { "id": "R-GGA-434316", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-434316", "resource": "Reactome", "description": "Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion" }, { "id": "R-GGA-500657", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-500657", "resource": "Reactome", "description": "Presynaptic function of Kainate receptors" } ], "orthologs": [ { "uniprot_canonical_ac": "P10687-1", "protein_name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1", "gene_name": "Plcb1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGAQPGVHALQLKPVCVSDSLKKGTKFVKWDDDSTIVTPIILRTDPQGFFFYWTDQNKETELLDLSLVKDARCGKHAKAPKDPKLRELLDVGNIGHLEQRMITVVYGPDLVNISHLNLVAFQEEVAKEWTNEVFSLATNLLAQNMSRDAFLEKAYTKLKLQVTPEGRIPLKNIYRLFSADRKRVETALEACSLPSSRNDSIPQEDFTPDVYRVFLNNLCPRPEIDNIFSEFGAKSKPYLTVDQMMDFINLKQRDPRLNEILYPPLKQEQVQVLIEKYEPNSSLAKKGQMSVDGFMRYLSGEENGVVSPEKLDLNEDMSQPLSHYFINSSHNTYLTAGQLAGNSSVEMYRQVLLSGCRCVELDCWKGRTAEEEPVITHGFTMTTEISFKEVIEAIAECAFKTSPFPILLSFENHVDSPKQQAKMAEYCRLIFGDALLMEPLEKYPLESGVPLPSPMDLMYKILVKNKKKSHKSSEGSGKKKLSEQASNTYSDSSSVFEPSSPGAGEADTESDDDDDDDDCKKSSMDEGTAGSEAMATEEMSNLVNYIQPVKFESFETSKKRNKSFEMSSFVETKGLEQLTKSPVEFVEYNKMQLSRIYPKGTRVDSSNYMPQLFWNAGCQMVALNFQTVDLAMQINMGMYEYNGKSGYRLKPEFMRRPDKHFDPFTEGIVDGIVANTLSVKIISGQFLSDKKVGTYVEVDMFGLPVDTRRKAFKTKTSQGNAVNPVWEEEPIVFKKVVLPSLACLRIAAYEEGGKFIGHRILPVQAIRPGYHYICLRNERNQPLMLPAVFVYIEVKDYVPDTYADVIEALSNPIRYVNLMEQRAKQLAALTLEDEEEVKKEADPGETSSEAPSETRTTPAENGVNHTATLAPKPPSQAPHSQPAPGSVKAPAKTEDLIQSVLTEVEAQTIEELKQQKSFVKLQKKHYKEMKDLVKRHHKKTTELIKEHTTKYNEIQNDYLRRRAALEKSAKKDSKKKSEPSSPDHGSSAIEQDLAALDAEMTQKLIDLKDKQQQQLLNLRQEQYYSEKYQKREHIKLLIQKLTDVAEECQNNQLKKLKEICEKEKKELKKKMDKKRQEKITEAKSKDKSQMEEEKTEMIRSYIQEVVQYIKRLEEAQSKRQEKLVEKHKEIRQQILDEKPKLQMELEQEYQDKFKRLPLEILEFVQEAMKGKVSEDSNHGSAPPSLASDPAKVNLKSPSSEEVQGENAGREFDTPL", "length": 1216 }, "evidence": [ { "id": "A0A1D5NZL7", "url": "https://omabrowser.org/oma/group/A0A1D5NZL7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P10894-1", "protein_name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1", "gene_name": "PLCB1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAGAQPGVHALQLKPVCVSDSLKKGTKFVKWEDDSTVVTPIILRTDPQGFFFYWTDQNKETELLDLSLVKDARCGKHAKAPKDPKLRELLDVGNIGRLEHRMITVVYGPDLVNISHLNLVAFQEEVAKEWTNEVFSLATNLLAQNMSRDAFLEKAYTKLKLQVTPEGRIPLKNIYRLFSADRKRVETALEACSLPSSRNDSIPQEDFTPEVYRVFLNNLCPRPEIDNIFSEFGAKSKPYLTVDQMMDFINLKQRDPRLNEILYPPLKQEQVQVLIEKYEPNNSLAKKGQISVDGFMRYLSGEENGVVSPEKLDLNEDMSQPLSHYFINSSHNTYLTAGQLAGNSSVEMYRQVLLSGCRCVELDCWKGRTAEEEPVITHGFTMTTEISFKEVIEAIAECAFKTSPFPILLSFENHVDSPKQQAKMAEYCRLIFGDALLMEPLDKYPLESGVPLPSPMDLMYKILVKNKKKSHKSSEGSGKKKLSEQASNTYSDSSSVFEPSSPGAGEADTESDDDDDDDDCKKSSMDEGTAGSEAMATEEMSNLVNYIQPVKFESFEISKKRNRSFEMSSFVETKGLEQLTKSPVEFVEYNKMQLSRIYPKGTRVDSSNYMPQLFWNAGCQMVALNFQTVDLAMQINMGMYEYNGKSGYRLKPEFMRRPDKHFDPFTEGIVDGIVANTLSVKIISGQFLSDKKVGTYVEVDMFGLPVDTRRKAFKTKTSQGNAVNPIWEEEPIVFKKVVLPSLACLRIAVYEEGGKFIGHRILPVQAIRPGYHYICLRNERNQPLMLPALFVYIEVKDYVPDTYADVIEALSNPIRYVNLMEQRAKQLAALTLEDEEEVKKEADPGETPSEAPSEARPTPAENGVNHTTSLTPKPPSQALHSQPAPGSVKAPAKTEDLIQSVLTEVEAQTIEELKQQKSFVKLQKKHYKEMKDLVKRHHKKTTDLIKEHTTKYNEIQNDYLRRRAALEKTAKKDNKKKSEPSSPDHVSSTIEQDLAALDAEMTQKLVDLKDKQQQQLLNLRQEQYYSEKYQKREHIKLLIQKLTDVAEECQNNQLKKLKEICEKEKKELKKKMDKKRQEKITEAKSKDKSQMEEEKTEMIRSYIQEVVQYIKRLEEAQSKRQEKLVEKHKEIRQQILDEKPKLQVELEQEYQDKFKRLPLEILEFVQEAMKGKISEDSNHSSAPPLMTSDSGKLNQKPPSSEELEGENPGKEFDTPL", "length": 1216 }, "evidence": [ { "id": "A0A1D5NZL7", "url": "https://omabrowser.org/oma/group/A0A1D5NZL7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q9NQ66-1", "protein_name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1", "gene_name": "PLCB1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAGAQPGVHALQLKPVCVSDSLKKGTKFVKWDDDSTIVTPIILRTDPQGFFFYWTDQNKETELLDLSLVKDARCGRHAKAPKDPKLRELLDVGNIGRLEQRMITVVYGPDLVNISHLNLVAFQEEVAKEWTNEVFSLATNLLAQNMSRDAFLEKAYTKLKLQVTPEGRIPLKNIYRLFSADRKRVETALEACSLPSSRNDSIPQEDFTPEVYRVFLNNLCPRPEIDNIFSEFGAKSKPYLTVDQMMDFINLKQRDPRLNEILYPPLKQEQVQVLIEKYEPNNSLARKGQISVDGFMRYLSGEENGVVSPEKLDLNEDMSQPLSHYFINSSHNTYLTAGQLAGNSSVEMYRQVLLSGCRCVELDCWKGRTAEEEPVITHGFTMTTEISFKEVIEAIAECAFKTSPFPILLSFENHVDSPKQQAKMAEYCRLIFGDALLMEPLEKYPLESGVPLPSPMDLMYKILVKNKKKSHKSSEGSGKKKLSEQASNTYSDSSSMFEPSSPGAGEADTESDDDDDDDDCKKSSMDEGTAGSEAMATEEMSNLVNYIQPVKFESFEISKKRNKSFEMSSFVETKGLEQLTKSPVEFVEYNKMQLSRIYPKGTRVDSSNYMPQLFWNAGCQMVALNFQTMDLAMQINMGMYEYNGKSGYRLKPEFMRRPDKHFDPFTEGIVDGIVANTLSVKIISGQFLSDKKVGTYVEVDMFGLPVDTRRKAFKTKTSQGNAVNPVWEEEPIVFKKVVLPTLACLRIAVYEEGGKFIGHRILPVQAIRPGYHYICLRNERNQPLTLPAVFVYIEVKDYVPDTYADVIEALSNPIRYVNLMEQRAKQLAALTLEDEEEVKKEADPGETPSEAPSEARTTPAENGVNHTTTLTPKPPSQALHSQPAPGSVKAPAKTEDLIQSVLTEVEAQTIEELKQQKSFVKLQKKHYKEMKDLVKRHHKKTTDLIKEHTTKYNEIQNDYLRRRAALEKSAKKDSKKKSEPSSPDHGSSTIEQDLAALDAEMTQKLIDLKDKQQQQLLNLRQEQYYSEKYQKREHIKLLIQKLTDVAEECQNNQLKKLKEICEKEKKELKKKMDKKRQEKITEAKSKDKSQMEEEKTEMIRSYIQEVVQYIKRLEEAQSKRQEKLVEKHKEIRQQILDEKPKLQVELEQEYQDKFKRLPLEILEFVQEAMKGKISEDSNHGSAPLSLSSDPGKVNHKTPSSEELGGDIPGKEFDTPL", "length": 1216 }, "evidence": [ { "id": "A0A1D5NZL7", "url": "https://omabrowser.org/oma/group/A0A1D5NZL7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9Z1B3-1", "protein_name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1", "gene_name": "Plcb1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAGAQPGVHALQLKPVCVSDSLKKGTKFVKWDDDSTIVTPIILRTDPQGFFFYWTDQNKETELLDLSLVKDARCGKHAKAPKDPKLRELLDVGNIGHLEQRMITVVYGPDLVNISHLNLVAFQEEVAKEWTNEVFSLATNLLAQNMSRDAFLEKAYTKLKLQVTPEGRIPLKNIYRLFSADRKRVETALEACSLPSSRNDSIPQEDFTPDVYRVFLNNLCPRPEIDNIFSEFGAKSKPYLTVDQMMDFINLKQRDPRLNEILYPPLKQEQVQVLIEKYEPNSSLAKKGQMSVDGFMRYLSGEENGVVSPEKLDLNEDMSQPLSHYFINSSHNTYLTAGQLAGNSSVEMYRQVLLSGCRCVELDCWKGRTAEEEPVITHGFTMTTEISFKEVIEAIAECAFKTSPFPILLSFENHVDSPKQQAKMAEYCRLIFGDALLMEPLEKYPLESGVPLPSPMDLMYKILVKNKKKSHKSSEGSGKKKLSEQASNTYSDSSSVFEPSSPGAGEADTESDDDDDDDDCKKSSMDEGTAGSEAMATEEMSNLVNYIQPVKFESFEISKKRNKSFEMSSFVETKGLEQLTKSPVEFVEYNKMQLSRIYPKGTRVDSSNYMPQLFWNAGCQMVALNFQTVDLAMQINMGMYEYNGKSGYRLKPEFMRRPDKHFDPFTEGIVDGIVANTLSVKIISGQFLSDKKVGTYVEVDMFGLPVDTRRKAFKTKTSQGNAVNPVWEEEPIVFKKVVLPSLACLRIAAYEEGGKFIGHRILPVQAIRPGYHYICLRNERNQPLTLPAVFVYIEVKDYVPDTYADVIEALSNPIRYVNLMEQRAKQLAALTLEDEEEVKKEADPGETSSEAPSETRTTPAENGVNHTASLAPKPPSQAPHSQPAPGSVKAPAKTEDLIQSVLTEVEAQTIEELKQQKSFVKLQKKHYKEMKDLVKRHHKKTTELIKEHTTKYNEIQNDYLRRRAALEKSAKKDSKKKSEPSSPDHGSSAIEQDLAALDAEMTQKLIDLKDKQQQQLLNLRQEQYYSEKYQKREHIKLLIQKLTDVAEECQNNQLKKLKEICEKEKKELKKKMDKKRQEKITEAKSKDKSQMEEEKTEMIRSYIQEVVQYIKRLEEAQSKRQEKLVEKHNEIRQQILDEKPKLQTELEQEYQDKFKRLPLEILEFVQEAMKGKISEDSNHGSAPPSLASDAAKVNLKSPSSEEIERENPGREFDTPL", "length": 1216 }, "evidence": [ { "id": "A0A1D5NZL7", "url": "https://omabrowser.org/oma/group/A0A1D5NZL7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 33, "go_terms": [ { "name": "positive regulation of acrosome reaction", "id": "GO:2000344", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000344", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NZL7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZL7" } ], "pmid": "" }, { "name": "interleukin-1-mediated signaling pathway", "id": "GO:0070498", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070498", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NZL7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZL7" } ], "pmid": "" }, { "name": "activation of meiosis involved in egg activation", "id": "GO:0060466", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060466", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NZL7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZL7" } ], "pmid": "" }, { "name": "negative regulation of monocyte extravasation", "id": "GO:2000438", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000438", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NZL7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZL7" } ], "pmid": "" }, { "name": "regulation of establishment of endothelial barrier", "id": "GO:1903140", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903140", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NZL7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZL7" } ], "pmid": "" }, { "name": "regulation of retrograde trans-synaptic signaling by endocanabinoid", "id": "GO:0099178", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099178", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NZL7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZL7" } ], "pmid": "" }, { "name": "G protein-coupled receptor signaling pathway", "id": "GO:0007186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007186", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NZL7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZL7" } ], "pmid": "" }, { "name": "phospholipase C-activating G protein-coupled acetylcholine receptor signaling pathway", "id": "GO:0007207", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007207", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NZL7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZL7" } ], "pmid": "" }, { "name": "memory", "id": "GO:0007613", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007613", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NZL7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZL7" } ], "pmid": "" }, { "name": "positive regulation of JNK cascade", "id": "GO:0046330", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046330", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NZL7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZL7" } ], "pmid": "" }, { "name": "G2/M transition of mitotic cell cycle", "id": "GO:0000086", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000086", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NZL7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZL7" } ], "pmid": "" }, { "name": "lipid catabolic process", "id": "GO:0016042", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016042", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NZL7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZL7" } ], "pmid": "" }, { "name": "cerebral cortex development", "id": "GO:0021987", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021987", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NZL7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZL7" } ], "pmid": "" }, { "name": "negative regulation of DNA-templated transcription", "id": "GO:0045892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045892", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NZL7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZL7" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NZL7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZL7" } ], "pmid": "" }, { "name": "interleukin-12-mediated signaling pathway", "id": "GO:0035722", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035722", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NZL7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZL7" } ], "pmid": "" }, { "name": "positive regulation of developmental growth", "id": "GO:0048639", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048639", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NZL7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZL7" } ], "pmid": "" }, { "name": "release of sequestered calcium ion into cytosol", "id": "GO:0051209", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051209", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NZL7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZL7" } ], "pmid": "" }, { "name": "fat cell differentiation", "id": "GO:0045444", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045444", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NZL7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZL7" } ], "pmid": "" }, { "name": "positive regulation of embryonic development", "id": "GO:0040019", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0040019", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NZL7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZL7" } ], "pmid": "" }, { "name": "phosphatidylinositol-mediated signaling", "id": "GO:0048015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048015", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NZL7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZL7" } ], "pmid": "" }, { "name": "positive regulation of G1/S transition of mitotic cell cycle", "id": "GO:1900087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900087", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NZL7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZL7" } ], "pmid": "" }, { "name": "insulin-like growth factor receptor signaling pathway", "id": "GO:0048009", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048009", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NZL7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZL7" } ], "pmid": "" }, { "name": "phosphatidylinositol metabolic process", "id": "GO:0046488", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046488", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NZL7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZL7" } ], "pmid": "" }, { "name": "positive regulation of myoblast differentiation", "id": "GO:0045663", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045663", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NZL7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZL7" } ], "pmid": "" }, { "name": "positive regulation of interleukin-12 production", "id": "GO:0032735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032735", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NZL7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZL7" } ], "pmid": "" }, { "name": "positive regulation of glycoprotein biosynthetic process", "id": "GO:0010560", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010560", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NZL7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZL7" } ], "pmid": "" }, { "name": "interleukin-15-mediated signaling pathway", "id": "GO:0035723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035723", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NZL7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZL7" } ], "pmid": "" }, { "name": "glutamate receptor signaling pathway", "id": "GO:0007215", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007215", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NZL7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZL7" } ], "pmid": "" }, { "name": "regulation of G protein-coupled receptor signaling pathway", "id": "GO:0008277", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008277", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NZL7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZL7" } ], "pmid": "" }, { "name": "regulation of fertilization", "id": "GO:0080154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0080154", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NZL7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZL7" } ], "pmid": "" }, { "name": "postsynaptic modulation of chemical synaptic transmission", "id": "GO:0099170", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099170", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NZL7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZL7" } ], "pmid": "" }, { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NZL7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZL7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 8, "go_terms": [ { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NZL7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZL7" } ], "pmid": "" }, { "name": "GABA-ergic synapse", "id": "GO:0098982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098982", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NZL7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZL7" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NZL7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZL7" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NZL7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZL7" } ], "pmid": "" }, { "name": "nuclear membrane", "id": "GO:0031965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031965", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NZL7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZL7" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NZL7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZL7" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NZL7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZL7" } ], "pmid": "" }, { "name": "postsynaptic cytosol", "id": "GO:0099524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099524", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NZL7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZL7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 7, "go_terms": [ { "name": "phosphatidylinositol-4,5-bisphosphate phospholipase C activity", "id": "GO:0004435", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004435", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NZL7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZL7" } ], "pmid": "" }, { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NZL7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZL7" } ], "pmid": "" }, { "name": "calmodulin binding", "id": "GO:0005516", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005516", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NZL7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZL7" } ], "pmid": "" }, { "name": "phosphatidylinositol-4,5-bisphosphate binding", "id": "GO:0005546", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005546", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NZL7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZL7" } ], "pmid": "" }, { "name": "enzyme binding", "id": "GO:0019899", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019899", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NZL7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZL7" } ], "pmid": "" }, { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NZL7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZL7" } ], "pmid": "" }, { "name": "lamin binding", "id": "GO:0005521", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005521", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NZL7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZL7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 114, "end_pos": 116, "annotation": "n_glycosylation_sequon" }, { "start_pos": 146, "end_pos": 148, "annotation": "n_glycosylation_sequon" }, { "start_pos": 200, "end_pos": 202, "annotation": "n_glycosylation_sequon" }, { "start_pos": 329, "end_pos": 331, "annotation": "n_glycosylation_sequon" }, { "start_pos": 344, "end_pos": 346, "annotation": "n_glycosylation_sequon" }, { "start_pos": 564, "end_pos": 566, "annotation": "n_glycosylation_sequon" }, { "start_pos": 867, "end_pos": 869, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "33179", "name": "", "equation": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + H2O = 1D-myo-inositol 1,4,5-trisphosphate + a 1,2-diacyl-sn-glycerol + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XBN2-1", "R4GFB3-1", "A0A8V0ZSL8-1", "A0A1D5NZL7-1", "A0A8V0YTH7-1", "A0A8V0ZCT0-1", "A0A8V0Z643-1", "A0A8V0ZKY1-1", "A0A8V0ZVU8-1", "A0A8V0XAT3-1", "A0A1D5PHP4-1", "A0A3Q2U9P4-1", "A0A8V0ZHR0-1", "A0A8V0ZUG3-1", "A0A8V1A5Y9-1", "Q2VRL0-1" ], "evidence": [ { "id": "33179", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/33179" } ] }, { "id": "43484", "name": "", "equation": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + H2O = 1D-myo-inositol 1-phosphate + a 1,2-diacyl-sn-glycerol + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "R4GFB3-1", "A0A1D5NZL7-1", "A0A8V0ZKY1-1", "A0A8V0ZVU8-1", "A0A3Q2U9P4-1", "A0A8V0ZHR0-1" ], "evidence": [ { "id": "43484", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/43484" } ] }, { "id": "R-GGA-111879", "name": "PIP2 hydrolysis", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "R4GFB3-1", "A0A8V0ZVU8-1", "A0A1D5NZL7-1" ], "evidence": [ { "id": "R-GGA-111879", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-111879" } ] }, { "id": "R-GGA-112037", "name": "Inactivation of PLC beta", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "R4GFB3-1", "A0A8V0ZVU8-1", "A0A1D5NZL7-1" ], "evidence": [ { "id": "R-GGA-112037", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-112037" } ] }, { "id": "R-GGA-114688", "name": "PLC-beta hydrolyses PIP2 to DAG and IP3", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "R4GFB3-1", "A0A8V0ZVU8-1", "A0A1D5NZL7-1" ], "evidence": [ { "id": "R-GGA-114688", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-114688" } ] }, { "id": "R-GGA-1855177", "name": "PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by cytosolic PLC[2] at the plasma membrane", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "R4GFB3-1", "A0A8V0ZVU8-1", "A0A1D5NZL7-1", "Q2VRL0-1" ], "evidence": [ { "id": "R-GGA-1855177", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1855177" } ] }, { "id": "R-GGA-398040", "name": "Gbeta:gamma activation of PLC beta", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZVU8-1", "A0A1D5NZL7-1" ], "evidence": [ { "id": "R-GGA-398040", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-398040" } ] }, { "id": "R-GGA-398193", "name": "PLC beta-mediated PIP2 hydrolysis", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZVU8-1", "A0A1D5NZL7-1" ], "evidence": [ { "id": "R-GGA-398193", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-398193" } ] }, { "id": "R-GGA-399998", "name": "Activated Phospholipase C beta-1 hydrolyzes 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZVU8-1", "A0A1D5NZL7-1" ], "evidence": [ { "id": "R-GGA-399998", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-399998" } ] }, { "id": "R-GGA-500717", "name": "Activation of GRIK3 homomer", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZVU8-1", "A0A1D5NZL7-1" ], "evidence": [ { "id": "R-GGA-500717", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-500717" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5NZL7", "gene_name": "PLCB1", "activity": [ { "ec_number": "3.1.4.11", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + H2O = 1D-myo-inositol 1,4,5-trisphosphate + a 1,2-diacyl-sn-glycerol + H(+).", "evidence": [ { "id": "A0A1D5NZL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZL7" } ] }, { "ec_number": "3.1.4.11", "activity": "", "evidence": [ { "id": "A0A1D5NZL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZL7" } ] } ] }, { "uniprot_ac": 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"snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A1D5NZW4-1", "uniprot_ac": "A0A1D5NZW4", "uniprot_id": "A0A1D5NZW4_CHICK", "mass": { "chemical_mass": 31765.0, "monoisotopic_mass": 31765.0 }, "refseq": { "ac": "XP_004937297", "name": "phospholipid phosphatase 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004937297" }, "gene_names": [ { "name": "PLPP1", "type": "recommended", "evidence": [ { "id": "A0A1D5NZW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZW4" } ] }, { "name": "PLPP1", "type": "synonym", "evidence": [ { "id": "XP_004937297", "database": "RefSeq", "url": 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"https://www.uniprot.org/uniprotkb/A0A1D5NZW4/entry#names_and_taxonomy" } ] }, { "name": "PAP2-alpha", "type": "synonym", "evidence": [ { "id": "A0A1D5NZW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZW4/entry#names_and_taxonomy" } ] }, { "name": "Phosphatidate phosphohydrolase type 2a", "type": "synonym", "evidence": [ { "id": "A0A1D5NZW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZW4/entry#names_and_taxonomy" } ] }, { "name": "Phosphatidic acid phosphatase 2a", "type": "synonym", "evidence": [ { "id": "A0A1D5NZW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZW4/entry#names_and_taxonomy" } ] }, { "name": "phospholipid phosphatase 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_004937297", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004937297" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052572.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004937297", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004937297" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NZW4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZW4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PLPP1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZW4", "locus": { "chromosome": "Z", "start_pos": 17347355, "end_pos": 17403851, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014125", "url": "https://www.ensembl.org/id/ENSGALG00010014125" } ] } } ], "crossref": [ { "id": "A0A1D5NZW4", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5NZW4", "database": 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"database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YUK9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUK9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YUK9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUK9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YUM1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUM1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YUM1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUM1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFDRTRLPFVALDVVCVVLAGLPLGVLNLAKIKPYQRGFFCNDDSIKYPFHDSTITSTVLYTVGFTLPILSIILGETLSVFYNHLHSNSFVRNNYIATIYKAIGTFIFGAAASQSLTDIAKYSIGRLRPHFLAVCQPDWTQINCSLGYIENIPCQGDKAKINEGRLSFYSGHSSFSMYCMLFLALYLQARMKGDWARLVRPTIQFGLIAASIYVGLSRVSDYKHHWSDVLTGLIQGALVAILIVVYVSDFFKVRGCTFQPKEDSHTTLHETPTNGNHFGSNHQP", "length": 284, "header": "tr|A0A1D5NZW4-1|A0A1D5NZW4_CHICK Isoform 1 of Phospholipid phosphatase 1 OS=Gallus gallus OX=9031 GN=PLPP1 PE=3 SV=2 CANONICAL=A0A1D5NZW4-1" }, "isoforms": [ { "isoform_ac": "A0A1D5NZW4-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZW4/entry#A0A1D5NZW4-1", "sequence": { "sequence": "MFDRTRLPFVALDVVCVVLAGLPLGVLNLAKIKPYQRGFFCNDDSIKYPFHDSTITSTVLYTVGFTLPILSIILGETLSVFYNHLHSNSFVRNNYIATIYKAIGTFIFGAAASQSLTDIAKYSIGRLRPHFLAVCQPDWTQINCSLGYIENIPCQGDKAKINEGRLSFYSGHSSFSMYCMLFLALYLQARMKGDWARLVRPTIQFGLIAASIYVGLSRVSDYKHHWSDVLTGLIQGALVAILIVVYVSDFFKVRGCTFQPKEDSHTTLHETPTNGNHFGSNHQP", "length": 284, "header": "tr|A0A1D5NZW4-1|A0A1D5NZW4_CHICK Isoform 1 of Phospholipid phosphatase 1 OS=Gallus gallus OX=9031 GN=PLPP1 PE=3 SV=2 CANONICAL=A0A1D5NZW4-1" }, "locus": { "chromosome": "Z", "start_pos": 17403523, "end_pos": 17348658, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033939.1", "url": "https://www.ensembl.org/id/ENSGALT00010033939.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019947.1", "url": "https://www.ensembl.org/id/ENSGALP00010019947.1" } ] } }, { "isoform_ac": "A0A8V0YGF7-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZW4/entry#A0A8V0YGF7-1", "sequence": { "sequence": "QYHHIHCPLHSGVHPAHFISGLPFAILNSRRIPFQRGVFCSDESIRYPYKEDTISYKLLAGILVPFSIIVIILGETLSVFYNHLHSNSFVRNNYIATIYKAIGTFIFGAAASQSLTDIAKYSIGRLRPHFLAVCQPDWTQINCSLGYIENIPCQGDKAKINEGRLSFYSGHSSFSMYCMLFLALYLQARMKGDWARLVRPTIQFGLIAASIYVGLSRVSDYKHHWSDVLTGLIQGALVAILIVVYVSDFFKVRGCTFQPKEDSHTTLHETPTNGNHFGSNHQP", "length": 283, "header": "tr|A0A8V0YGF7-1|A0A8V0YGF7_CHICK Computationally mapped isoform of Phospholipid phosphatase 1 OS=Gallus gallus OX=9031 GN=PLPP1 PE=3 SV=1 CANONICAL=A0A1D5NZW4-1" }, "locus": { "chromosome": "Z", "start_pos": 17389509, "end_pos": 17348658, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033932.1", "url": "https://www.ensembl.org/id/ENSGALT00010033932.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019944.1", "url": "https://www.ensembl.org/id/ENSGALP00010019944.1" } ] } }, { "isoform_ac": "A0A8V0YMH6-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZW4/entry#A0A8V0YMH6-1", "sequence": { "sequence": "MDSMFSPPSAGRKAVFALHSTAELSGLSAAGLPFAILNSRRIPFQRGVFCSDESIRYPYKEDTISYKLLAGILVPFSIIVIILGETLSVFYNHLHSNSFVRNNYIATIYKAIGTFIFGAAASQSLTDIAKYSIGRLRPHFLAVCQPDWTQINCSLGYIENIPCQGDKAKINEGRLSFYSGHSSFSMYCMLFLALYLQARMKGDWARLVRPTIQFGLIAASIYVGLSRVSDYKHHWSDVLTGLIQGALVAILIVVYVSDFFKVRGCTFQPKEDSHTTLHETPTNGNHFGSNHQP", "length": 293, "header": "tr|A0A8V0YMH6-1|A0A8V0YMH6_CHICK Computationally mapped isoform of Phospholipid phosphatase 1 OS=Gallus gallus OX=9031 GN=PLPP1 PE=3 SV=1 CANONICAL=A0A1D5NZW4-1" }, "locus": { "chromosome": "Z", "start_pos": 17382101, "end_pos": 17348658, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033919.1", "url": "https://www.ensembl.org/id/ENSGALT00010033919.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019938.1", "url": "https://www.ensembl.org/id/ENSGALP00010019938.1" } ] } }, { "isoform_ac": "A0A8V0YMI2-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZW4/entry#A0A8V0YMI2-1", "sequence": { "sequence": "MFDRTRLPFVALDVVCVVLAGLPLGVLNLAKIKPYQRGFFCNDDSIKYPFHDSTITSTVLYTVGFTLPILSQVHSCHSVADYQTADDVQQYRPCLSDCDVPKYPCCATRSSELLELWSCAASHSSGITLRKFSSSGLPFAILNSRRIPFQRGVFCSDESIRYPYKEDTISYKLLAGILVPFSIIVIILGETLSVFYNHLHSNSFVRNNYIATIYKAIGTFIFGAAASQSLTDIAKYSIGRLRPHFLAVCQPDWTQINCSLGYIENIPCQGDKAKINEGRLSFYSGHSSFSMYCMLFLALYLQARMKGDWARLVRPTIQFGLIAASIYVGLSRVSDYKHHWSDVLTGLIQGALVAILIVVYVSDFFKVRGCTFQPKEDSHTTLHETPTNGNHFGSNHQP", "length": 398, "header": "tr|A0A8V0YMI2-1|A0A8V0YMI2_CHICK Computationally mapped isoform of Phospholipid phosphatase 1 OS=Gallus gallus OX=9031 GN=PLPP1 PE=3 SV=1 CANONICAL=A0A1D5NZW4-1" }, "locus": { "chromosome": "Z", "start_pos": 17403523, "end_pos": 17348658, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033930.1", "url": "https://www.ensembl.org/id/ENSGALT00010033930.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019943.1", "url": "https://www.ensembl.org/id/ENSGALP00010019943.1" } ] } }, { "isoform_ac": "A0A8V0YMT3-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZW4/entry#A0A8V0YMT3-1", "sequence": { "sequence": "RRQAGLPLGVLNLAKIKPYQRGFFCNDDSIKYPFHDSTITSTVLYTVGFTLPILSIILGETLSVFYNHLHSNSFVRNNYIATIYKAIGTFIFGAAASQSLTDIAKYSIGRLRPHFLAVCQPDWTQINCSLGYIENIPCQGDKAKINEGRLSFYSGHSSFSMYCMLFLALYLQARMKGDWARLVRPTIQFGLIAASIYVGLSRVSDYKHHWSDVLTGLIQGALVAILIVVYVSDFFKVRGCTFQPKEDSHTTLHETPTNGNHFGSNHQP", "length": 268, "header": "tr|A0A8V0YMT3-1|A0A8V0YMT3_CHICK Computationally mapped isoform of Phospholipid phosphatase 1 OS=Gallus gallus OX=9031 GN=PLPP1 PE=3 SV=1 CANONICAL=A0A1D5NZW4-1" }, "locus": { "chromosome": "Z", "start_pos": 17392332, "end_pos": 17348658, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033925.1", "url": "https://www.ensembl.org/id/ENSGALT00010033925.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019941.1", "url": "https://www.ensembl.org/id/ENSGALP00010019941.1" } ] } }, { "isoform_ac": "A0A8V0YUK9-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZW4/entry#A0A8V0YUK9-1", "sequence": { "sequence": "RTAGLPLGVLNLAKIKPYQRGFFCNDDSIKYPFHDSTITSTVLYTVGFTLPILSIILGETLSVFYNHLHSNSFVRNNYIATIYKAIGTFIFGAAASQSLTDIAKYSIGRLRPHFLAVCQPDWTQINCSLGYIENIPCQGDKAKINEGRLSFYSGHSSFSMYCMLFLALYLQARMKGDWARLVRPTIQFGLIAASIYVGLSRVSDYKHHWSDVLTGLIQGALVAILIVVYVSDFFKVRGCTFQPKEDSHTTLHETPTNGNHFGSNHQP", "length": 267, "header": "tr|A0A8V0YUK9-1|A0A8V0YUK9_CHICK Computationally mapped isoform of Phospholipid phosphatase 1 OS=Gallus gallus OX=9031 GN=PLPP1 PE=3 SV=1 CANONICAL=A0A1D5NZW4-1" }, "locus": { "chromosome": "Z", "start_pos": 17390642, "end_pos": 17348658, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033922.1", "url": "https://www.ensembl.org/id/ENSGALT00010033922.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019940.1", "url": "https://www.ensembl.org/id/ENSGALP00010019940.1" } ] } }, { "isoform_ac": "A0A8V0YUM1-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZW4/entry#A0A8V0YUM1-1", "sequence": { "sequence": "RSAGAGRRGAGAIGSGAAELSCPPPLPSRPSGSGCHRVRRSRRAPPACLTGRGCPSWRWTWSAWCSRGVFCSDESIRYPYKEDTISYKLLAGILVPFSIIVIILGETLSVFYNHLHSNSFVRNNYIATIYKAIGTFIFGAAASQSLTDIAKYSIGRLRPHFLAVCQPDWTQINCSLGYIENIPCQGDKAKINEGRLSFYSGHSSFSMYCMLFLALYLQARMKGDWARLVRPTIQFGLIAASIYVGLSRVSDYKHHWSDVLTGLIQGALVAILIVVYVSDFFKVRGCTFQPKEDSHTTLHETPTNGNHFGSNHQP", "length": 314, "header": "tr|A0A8V0YUM1-1|A0A8V0YUM1_CHICK Computationally mapped isoform of Phospholipid phosphatase 1 OS=Gallus gallus OX=9031 GN=PLPP1 PE=3 SV=1 CANONICAL=A0A1D5NZW4-1" }, "locus": { "chromosome": "Z", "start_pos": 17403663, "end_pos": 17348658, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033943.1", "url": "https://www.ensembl.org/id/ENSGALT00010033943.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019950.1", "url": "https://www.ensembl.org/id/ENSGALP00010019950.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:427138", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427138", "resource": "KEGG Pathway" }, { "id": "R-GGA-9845614", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9845614", "resource": "Reactome", "description": "Sphingolipid catabolism" } ], "orthologs": [ { "uniprot_canonical_ac": "A0AAA9STE8-1", "protein_name": "Phospholipid phosphatase 1", "gene_name": "PLPP1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MFDKTRLPYVALDVLCVLLASMPMAVLNLGQIDPFQRGFFCKDNSIQYPYHDGTITTTVLSTVGLGLPISSMIVGETLSVYFSLLHSNSFIRNNYIATIYKAIGTFLFGAAASQSLTDIAKYSIGRLRPHFLDVCDPDWSKINCSDGYIENYICRGNAQKVKEGRLSFYSGHSSFSMYCMMFVALYLQARMKGDWARLLRPTLQFGLVAASIYVGLSRVSDYKHHWSDVLTGLIQGALVAILVAVYVSDFFKKRSSPFKERKEEDSHTTLHETPTTGNHYRNSHQP", "length": 286 }, "evidence": [ { "id": "A0A1D5NZW4", "url": "https://omabrowser.org/oma/group/A0A1D5NZW4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0AC58GLC3-1", "protein_name": "Phospholipid phosphatase 1", "gene_name": "plpp1a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MQLYWGKYSTLLTFVLFLSLLFLLVGLPFAILTIQHKSFKRGFFCNDDSIKYPYKEDTISYQLLGGVMIPVTLLTMIIGECLSVYLNRIKSNSFCNGYVACVYKAIGTFVFGAAISQSLTDIAKYSIGRLRPHFLDVCKPDWSKINCTAGAYIEDFVCTGKESVVNEGRLSFYSGHSSFSMYCMLFLALYLQARMQAEWARLLRPTLQFFLIAASVYTGLSRVSDYKHHWSDVLTGLIQGAIVALLVVFFVSDFFKKKVEPQKETEIPHTTLQETPTNGNHYDNPN", "length": 286 }, "evidence": [ { "id": "A0A1D5NZW4", "url": "https://omabrowser.org/oma/group/A0A1D5NZW4/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "O08564-1", "protein_name": "Phospholipid phosphatase 1", "gene_name": "Plpp1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFDKPRLPYVVLDVICVLLAGLPFIILTSRHTPFQRGVFCTDESIKYPYREDTIPYALLGGIVIPFCIIVMITGETLSVYFNVLHSNSFVSNHYIATIYKAVGAFLFGASASQSLTDIAKYSIGRLRPHFLAVCNPDWSKINCSDGYIENFVCQGNEQKVREGRLSFYSGHSSFSMYCMLFVALYLQARMKGDWARLLRPMLQFGLVALSIYVGLSRVSDYKHHWSDVLIGLIQGAVVAILVVLYVTDFFKTTESNKERKEDSHTTLHETTNRQSYARNHEP", "length": 282 }, "evidence": [ { "id": "A0A1D5NZW4", "url": "https://omabrowser.org/oma/group/A0A1D5NZW4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O14494-1", "protein_name": "Phospholipid phosphatase 1", "gene_name": "PLPP1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MFDKTRLPYVALDVLCVLLAGLPFAILTSRHTPFQRGVFCNDESIKYPYKEDTIPYALLGGIIIPFSIIVIILGETLSVYCNLLHSNSFIRNNYIATIYKAIGTFLFGAAASQSLTDIAKYSIGRLRPHFLDVCDPDWSKINCSDGYIEYYICRGNAERVKEGRLSFYSGHSSFSMYCMLFVALYLQARMKGDWARLLRPTLQFGLVAVSIYVGLSRVSDYKHHWSDVLTGLIQGALVAILVAVYVSDFFKERTSFKERKEEDSHTTLHETPTTGNHYPSNHQP", "length": 284 }, "evidence": [ { "id": "A0A1D5NZW4", "url": "https://omabrowser.org/oma/group/A0A1D5NZW4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q61469-1", "protein_name": "Phospholipid phosphatase 1", "gene_name": "Plpp1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFDKTRLPYVALDVICVLLAGLPFAILTSRHTPFQRGIFCNDDSIKYPYKEDTIPYALLGGIVIPFCIIVMSIGESLSVYFNVLHSNSFVGNPYIATIYKAVGAFLFGVSASQSLTDIAKYTIGSLRPHFLAICNPDWSKINCSDGYIEDYICQGNEEKVKEGRLSFYSGHSSFSMYCMLFVALYLQARMKGDWARLLRPMLQFGLIAFSIYVGLSRVSDYKHHWSDVTVGLIQGAAMAILVALYVSDFFKDTHSYKERKEEDPHTTLHETASSRNYSTNHEP", "length": 283 }, "evidence": [ { "id": "A0A1D5NZW4", "url": "https://omabrowser.org/oma/group/A0A1D5NZW4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "lysophosphatidic acid phosphatase activity", "id": "GO:0052642", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0052642", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NZW4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZW4" } ], "pmid": "" }, { "name": "phosphatidate phosphatase activity", "id": "GO:0008195", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008195", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NZW4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZW4" } ], "pmid": "" }, { "name": "diacylglycerol diphosphate phosphatase activity", "id": "GO:0000810", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000810", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NZW4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZW4" } ], "pmid": "" }, { "name": "sphingosine-1-phosphate phosphatase activity", "id": "GO:0042392", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042392", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NZW4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZW4" } ], "pmid": "" }, { "name": "ceramide-1-phosphate phosphatase activity", "id": "GO:0106235", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106235", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NZW4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZW4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "apical plasma membrane", "id": "GO:0016324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016324", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NZW4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZW4" } ], "pmid": "" }, { "name": "caveola", "id": "GO:0005901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005901", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NZW4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZW4" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NZW4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZW4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "phospholipid metabolic process", "id": "GO:0006644", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006644", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NZW4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZW4" } ], "pmid": "" }, { "name": "phospholipid dephosphorylation", "id": "GO:0046839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046839", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NZW4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZW4" } ], "pmid": "" }, { "name": "sphingosine metabolic process", "id": "GO:0006670", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006670", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NZW4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZW4" } ], "pmid": "" }, { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NZW4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZW4" } ], "pmid": "" }, { "name": "ceramide metabolic process", "id": "GO:0006672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006672", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NZW4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZW4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 143, "end_pos": 145, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "27429", "name": "", "equation": "a 1,2-diacyl-sn-glycero-3-phosphate + H2O = a 1,2-diacyl-sn-glycerol + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XEH7-1", "A0A8V0XAG3-1", "A0A1D5NZW4-1", "A0A8V0XAH3-1", "E1C944-1", "A0A8V1AEZ8-1" ], "evidence": [ { "id": "27429", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/27429" } ] }, { "id": "27449", "name": "", "equation": "a 1,2-diacyl-sn-glycerol 3-diphosphate + H2O = a 1,2-diacyl-sn-glycero-3-phosphate + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A1D5NZW4-1", "A0A8V0XAH3-1" ], "evidence": [ { "id": "27449", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/27449" } ] }, { "id": "27518", "name": "", "equation": "sphing-4-enine 1-phosphate + H2O = sphing-4-enine + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A1D5NZW4-1", "E1C944-1", "A0A8V1AEZ8-1" ], "evidence": [ { "id": "27518", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/27518" } ] }, { "id": "33155", "name": "", "equation": "a 1-acyl-sn-glycero-3-phosphate + H2O = a 1-acyl-sn-glycerol + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A1D5NZW4-1" ], "evidence": [ { "id": "33155", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/33155" } ] }, { "id": "33743", "name": "", "equation": "an N-acylsphing-4-enine 1-phosphate + H2O = an N-acylsphing-4-enine + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A1D5NZW4-1", "E1C944-1", "A0A8V1AEZ8-1" ], "evidence": [ { "id": "33743", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/33743" } ] }, { "id": "39835", "name": "", "equation": "1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + H2O = 1-(9Z-octadecenoyl)-sn-glycerol + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A1D5NZW4-1", "A0A8V0XAH3-1" ], "evidence": [ { "id": "39835", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/39835" } ] }, { "id": "41255", "name": "", "equation": "1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphate + H2O = 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycerol + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A1D5NZW4-1" ], "evidence": [ { "id": "41255", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/41255" } ] }, { "id": "43236", "name": "", "equation": "1,2-dihexadecanoyl-sn-glycero-3-phosphate + H2O = 1,2-dihexadecanoyl-sn-glycerol + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A1D5NZW4-1", "E1C944-1", "A0A8V1AEZ8-1" ], "evidence": [ { "id": "43236", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/43236" } ] }, { "id": "43244", "name": "", "equation": "1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphate + H2O = 1,2-di-(9Z-octadecenoyl)-sn-glycerol + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A1D5NZW4-1", "E1C944-1", "A0A8V1AEZ8-1" ], "evidence": [ { "id": "43244", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/43244" } ] }, { "id": "46736", "name": "", "equation": "a monoacyl-sn-glycero-3-phosphate + H2O = a monoacylglycerol + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A1D5NZW4-1", "E1C944-1", "A0A8V1AEZ8-1" ], "evidence": [ { "id": "46736", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/46736" } ] }, { "id": "50884", "name": "", "equation": "(9Z)-octadecenoyl-sn-glycero-3-phosphate + H2O = (9Z-octadecenoyl)-glycerol + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A1D5NZW4-1", "E1C944-1", "A0A8V1AEZ8-1" ], "evidence": [ { "id": "50884", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/50884" } ] }, { "id": "62040", "name": "", "equation": "N-(octanoyl)-sphing-4-enine-1-phosphate + H2O = N-octanoylsphing-4-enine + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A1D5NZW4-1", "E1C944-1", "A0A8V1AEZ8-1" ], "evidence": [ { "id": "62040", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/62040" } ] }, { "id": "62160", "name": "", "equation": "N-(9Z-octadecenoyl)-ethanolamine phosphate + H2O = N-(9Z-octadecenoyl) ethanolamine + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A1D5NZW4-1", "E1C944-1", "A0A8V1AEZ8-1" ], "evidence": [ { "id": "62160", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/62160" } ] }, { "id": "R-GGA-428690", "name": "PLPP1 dephosphorylates extracellular sphingosine-1-phosphate", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "extracellular region, plasma membrane", "input_participant_list": [ "R-ALL-419305" ], "output_participant_list": [ "R-ALL-1132148" ], "enzyme_list": [ "A0A1D5NZW4-1" ], "evidence": [ { "id": "R-GGA-428690", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-428690" } ] }, { "id": "R-GGA-428696", "name": "PLPP1,2,3 dephosphorylate cytosolic sphingosine-1-phosphate", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1C944-1", "A0A8V1AEZ8-1", "A0A1D5NZW4-1" ], "evidence": [ { "id": "R-GGA-428696", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-428696" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-1132148", "participant_name": "sphingosine [cytoplasm]", "crossref": [ { "id": "ZINC000008195650", "database": "ZINC", "url": "" }, { "id": "HMDB0062807", "database": "HMDB Metabolite", "url": "" }, { "id": "57756", "database": "ChEBI", "url": "" } ] }, { "participant_id": "R-ALL-419305", "participant_name": "C18-S1P [extracellular region]", "crossref": [ { "id": "60119", "database": "ChEBI", "url": "" }, { "id": "ZINC000008860500", "database": "ZINC", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5NZW4", "gene_name": "PLPP1", "activity": [ { "ec_number": "3.1.3.4", "activity": "1-O-alkyl-2-acyl-sn-glycero-3-phosphate + H2O = 1-O-alkyl-2-acyl-sn-glycerol + phosphate.", "evidence": [ { "id": "A0A1D5NZW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZW4" } ] }, { "ec_number": "3.1.3.106", "activity": "a 1-acyl-sn-glycero-3-phosphate + H2O = a 1-acyl-sn-glycerol + phosphate.", "evidence": [ { "id": "A0A1D5NZW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZW4" } ] }, { "ec_number": "3.6.1.75", "activity": "a 1,2-diacyl-sn-glycerol 3-diphosphate + H2O = a 1,2-diacyl-sn-glycero-3-phosphate + phosphate + H(+).", "evidence": [ { "id": "A0A1D5NZW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZW4" } ] }, { "ec_number": "3.1.3.106", "activity": "", "evidence": [ { "id": "A0A1D5NZW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZW4" } ] }, { "ec_number": "3.1.3.4", "activity": "", "evidence": [ { "id": "A0A1D5NZW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZW4" } ] }, { "ec_number": "3.6.1.75", "activity": "", "evidence": [ { "id": "A0A1D5NZW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZW4" } ] } ] }, { "uniprot_ac": "A0A8V0XAG3", "gene_name": "LPIN2", "activity": [ { "ec_number": "3.1.3.4", "activity": "1-O-alkyl-2-acyl-sn-glycero-3-phosphate + H2O = 1-O-alkyl-2-acyl-sn-glycerol + phosphate.", "evidence": [ { "id": "A0A8V0XAG3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XAG3" } ] }, { "ec_number": "3.1.3.4", "activity": "", "evidence": [ { "id": "A0A8V0XAG3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XAG3" } ] } ] }, { "uniprot_ac": "A0A8V0XAH3", "gene_name": "PLPP4", "activity": [ { "ec_number": "3.1.3.4", "activity": "1-O-alkyl-2-acyl-sn-glycero-3-phosphate + H2O = 1-O-alkyl-2-acyl-sn-glycerol + phosphate.", "evidence": [ { "id": "A0A8V0XAH3", "database": "UniProtKB", 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"BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.1.3.4" } ] }, { "ec_number": "3.1.3.106", "ec_name": "a 1-acyl-sn-glycero-3-phosphate + H2O = a 1-acyl-sn-glycerol + phosphate.", "evidence": [ { "id": "3.1.3.106", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.106" }, { "id": "3.1.3.106", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.1.3.106" } ] }, { "ec_number": "3.6.1.75", "ec_name": "a 1,2-diacyl-sn-glycerol 3-diphosphate + H2O = a 1,2-diacyl-sn-glycero-3-phosphate + phosphate + H(+).", "evidence": [ { "id": "3.6.1.75", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.75" }, { "id": "3.6.1.75", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.6.1.75" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": 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[ { "id": "NP_001035179", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001035179" } ] }, { "name": "spinal and bulbar muscular atrophy", "type": "synonym", "evidence": [ { "id": "NP_001035179", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001035179" } ] }, { "name": "testicular feminization", "type": "synonym", "evidence": [ { "id": "NP_001035179", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001035179" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AB193190.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000071.1. On Sep 23, 2021 this sequence version replaced NP_001035179.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001035179", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001035179" } ] }, { "annotation": "A full-length androgen receptor (AR) cDNA from chicken (Gallus gallus) gonads was cloned and characterized.", "evidence": [ { "database": "RefSeq", "id": "NP_001035179", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001035179" }, { "database": "PubMed", "id": "16480982", "url": "https://glygen.org/publication/PubMed/16480982" } ] }, { "annotation": "Androgen receptor in early developmental stages of the nervous system; androgen receptor protein was located in the nucleus of neuroepithelial cells throughout the neural tube", "evidence": [ { "database": "RefSeq", "id": "NP_001035179", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001035179" }, { "database": "PubMed", "id": "19262415", "url": "https://glygen.org/publication/PubMed/19262415" } ] }, { "annotation": "Androgens and AR signaling are essential for the development of lacunae and cortical cords in gonads of female embryos.", "evidence": [ { "database": "RefSeq", "id": "NP_001035179", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001035179" }, { "database": "PubMed", "id": "28087386", "url": "https://glygen.org/publication/PubMed/28087386" } ] }, { "annotation": "Cell-specific distribution of ERalpha and AR in the anterior pituitary from adult cockerels by immunohistochemistry", "evidence": [ { "database": "RefSeq", "id": "NP_001035179", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001035179" }, { "database": "PubMed", "id": "22453555", "url": "https://glygen.org/publication/PubMed/22453555" } ] }, { "annotation": "Testosterone Promotes the Proliferation of Chicken Embryonic Myoblasts Via Androgen Receptor Mediated PI3K/Akt Signaling Pathway. Publication Status: Online-Only", "evidence": [ { "database": "RefSeq", "id": "NP_001035179", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001035179" }, { "database": "PubMed", "id": "32050491", "url": "https://glygen.org/publication/PubMed/32050491" } ] }, { "annotation": "The androgen receptor might play a role in vocal development and that the molecular mechanism regulating the androgen receptor expression in the vocal areas might be important in the evolution of vocal learning.", "evidence": [ { "database": "RefSeq", "id": "NP_001035179", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001035179" }, { "database": "PubMed", "id": "18394591", "url": "https://glygen.org/publication/PubMed/18394591" } ] }, { "annotation": "Vitamin D3 and androgen receptors may be directly or indirectly involved in the development of the epididymal lithiasis in chickens.", "evidence": [ { "database": "RefSeq", "id": "NP_001035179", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001035179" }, { "database": "PubMed", "id": "18164879", "url": "https://glygen.org/publication/PubMed/18164879" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P088", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P088" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "AR", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P088", "locus": { "chromosome": "4", "start_pos": 454750, "end_pos": 408217, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010016880", "url": "https://www.ensembl.org/id/ENSGALG00010016880" } ] } } ], "crossref": [ { "id": "A0A1D5P088", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5P088", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000030879", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000030879", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd07073", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07073", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd07173", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07173", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "422165", "url": "https://www.ncbi.nlm.nih.gov/gene/422165", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000536", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000536", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001103", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001103", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001628", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001628", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001723", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001723", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013088", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013088", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035500", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035500", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050200", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050200", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:422165", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422165", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SHMEGYE", "url": "https://omabrowser.org/oma/group/SHMEGYE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5P088", "url": "https://www.orthodb.org/?gene=A0A1D5P088", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48092", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48092", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00104", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00104", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00105", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00105", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02166", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02166", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-3371497", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3371497", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-383280", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-383280", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-4090294", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4090294", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5689880", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5689880", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-8940973", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8940973", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001035179", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001035179", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5P088", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P088", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5P088-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P088-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEVQLGIGRVYPRPPGRTFRGVFQTFFQSVCEAFQAPRDEPGPGLPAPGAPCPQSPRPPPVASPAFLPLPEPRAAARPAMGSPFPCAGDLKELLGEPGVLPLLPPEAEPGAGRAEPALKEDFLGDSAKELCKAVSASMGLAVETLEAPREPPPREDCMFALPGGPPRAPRPDAAEPPEPPAPAAFKGSGAEAALAVEVPAGLPLYRVSPPPEEPPGRDCFVLPPPARIKLESPPEPAAVGAWGSPVPAPPWPSFFADEGQLYGPCAEPPPGAFGCGRPENADFAADAWHPMARAPYAAPGSCIKSELGPWAEGYAGAYGDVRLEAGREHILPIDYYFPPQKTCLICGDEASGCHYGALTCGSCKVFFKRAAEGKQKYLCASRNDCTIDKFRRKNCPSCRLRKCYEAGMTLGARKLKKLGSLKTQDEAEAASSSSPTEEQAPKMVMTHVNGFECQPIFLNVLEAIEPAVVCAGHDNSQPDSFSNLLSSLNELGERQLVYVVKWAKALPGFRNLHVDDQMSIIQYSWMGLMIFAMGWRSFTNVNSRMLYFAPDLVFNEYRMHKSRMYSQCVRMRQLSQEFGWLQITPQEFLCMKALLFFSIIPVDGLKNQKLFDELRMNYIKELDRIIACKRKNPTSCSRRFYQLTKVLDSVHPIAKDLHQFTFDLLIKAHMVSVDYPEMMAEIISVQVPKILSGKVKPIYFHAE", "length": 703, "header": "tr|A0A1D5P088-1|A0A1D5P088_CHICK Isoform 1 of Androgen receptor OS=Gallus gallus OX=9031 GN=AR PE=1 SV=1 CANONICAL=A0A1D5P088-1" }, "isoforms": [ { "isoform_ac": "A0A1D5P088-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P088/entry#A0A1D5P088-1", "sequence": { "sequence": "MEVQLGIGRVYPRPPGRTFRGVFQTFFQSVCEAFQAPRDEPGPGLPAPGAPCPQSPRPPPVASPAFLPLPEPRAAARPAMGSPFPCAGDLKELLGEPGVLPLLPPEAEPGAGRAEPALKEDFLGDSAKELCKAVSASMGLAVETLEAPREPPPREDCMFALPGGPPRAPRPDAAEPPEPPAPAAFKGSGAEAALAVEVPAGLPLYRVSPPPEEPPGRDCFVLPPPARIKLESPPEPAAVGAWGSPVPAPPWPSFFADEGQLYGPCAEPPPGAFGCGRPENADFAADAWHPMARAPYAAPGSCIKSELGPWAEGYAGAYGDVRLEAGREHILPIDYYFPPQKTCLICGDEASGCHYGALTCGSCKVFFKRAAEGKQKYLCASRNDCTIDKFRRKNCPSCRLRKCYEAGMTLGARKLKKLGSLKTQDEAEAASSSSPTEEQAPKMVMTHVNGFECQPIFLNVLEAIEPAVVCAGHDNSQPDSFSNLLSSLNELGERQLVYVVKWAKALPGFRNLHVDDQMSIIQYSWMGLMIFAMGWRSFTNVNSRMLYFAPDLVFNEYRMHKSRMYSQCVRMRQLSQEFGWLQITPQEFLCMKALLFFSIIPVDGLKNQKLFDELRMNYIKELDRIIACKRKNPTSCSRRFYQLTKVLDSVHPIAKDLHQFTFDLLIKAHMVSVDYPEMMAEIISVQVPKILSGKVKPIYFHAE", "length": 703, "header": "tr|A0A1D5P088-1|A0A1D5P088_CHICK Isoform 1 of Androgen receptor OS=Gallus gallus OX=9031 GN=AR PE=1 SV=1 CANONICAL=A0A1D5P088-1" }, "locus": { "chromosome": "4", "start_pos": 449756, "end_pos": 408443, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040723.1", "url": "https://www.ensembl.org/id/ENSGALT00010040723.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023688.1", "url": "https://www.ensembl.org/id/ENSGALP00010023688.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Cloning and expression analysis of androgen receptor gene in chicken embryogenesis.", "journal": "FEBS letters", "date": "2006-03-06", "authors": "Katoh Hironori, Ogino Yukiko, Yamada Gen", "evidence": [ { "database": "RefSeq", "id": "NP_001035179", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001035179" } ], "reference": [ { "type": "PubMed", "id": "16480982", "url": "https://glygen.org/publication/PubMed/16480982" } ] }, { "title": "Vitamin D3 and androgen receptors in testis and epididymal region of roosters (Gallus domesticus) as affected by epididymal lithiasis.", "journal": "Animal reproduction science", "date": "2008-12", "authors": "Oliveira Andr\u00e9 G, Dornas Rubem A P, Kalapothakis Evanguedes, Hess Rex A, Mahecha Germ\u00e1n A B, Oliveira Cleida A", "evidence": [ { "database": "RefSeq", "id": "NP_001035179", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001035179" } ], "reference": [ { "type": "PubMed", "id": "18164879", "url": "https://glygen.org/publication/PubMed/18164879" } ] }, { "title": "Vocal area-related expression of the androgen receptor in the budgerigar (Melopsittacus undulatus) brain.", "journal": "Brain research", "date": "2008-05-07", "authors": "Matsunaga Eiji, Okanoya Kazuo", "evidence": [ { "database": "RefSeq", "id": "NP_001035179", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001035179" } ], "reference": [ { "type": "PubMed", "id": "18394591", "url": "https://glygen.org/publication/PubMed/18394591" } ] }, { "title": "Androgen receptor in the neural tube of the mouse and chicken embryo.", "journal": "Neuroreport", "date": "2009-03-25", "authors": "M\u00e9ndez Carmen, N\u00fa\u00f1ez-Vidales Rodrigo, Mondrag\u00f3n-Huerta Carmen, G\u00f3mora Mar\u00eda J, Pedernera Enrique", "evidence": [ { "database": "RefSeq", "id": "NP_001035179", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001035179" } ], "reference": [ { "type": "PubMed", "id": "19262415", "url": "https://glygen.org/publication/PubMed/19262415" } ] }, { "title": "Cell-specific distributions of estrogen receptor alpha (ER\u03b1) and androgen receptor (AR) in anterior pituitary glands from adult cockerels as revealed by immunohistochemistry.", "journal": "Cell and tissue research", "date": "2012-06", "authors": "Sun Dehao, Cui Tongtong, Luo Haoshu, Li Ruiguo, Cui Sheng, Liu Jiali", "evidence": [ { "database": "RefSeq", "id": "NP_001035179", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001035179" } ], "reference": [ { "type": "PubMed", "id": "22453555", "url": "https://glygen.org/publication/PubMed/22453555" } ] }, { "title": "Androgens and androgen receptor signaling contribute to ovarian development in the chicken embryo.", "journal": "Molecular and cellular endocrinology", "date": "2017-03-05", "authors": "Tanaka Ryoma, Izumi Hiroe, Kuroiwa Asato", "evidence": [ { "database": "RefSeq", "id": "NP_001035179", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001035179" } ], "reference": [ { "type": "PubMed", "id": "28087386", "url": "https://glygen.org/publication/PubMed/28087386" } ] }, { "title": "Testosterone Promotes the Proliferation of Chicken Embryonic Myoblasts Via Androgen Receptor Mediated PI3K/Akt Signaling Pathway.", "journal": "International journal of molecular sciences", "date": "2020-02-09", "authors": "Li Dongfeng, Wang Qin, Shi Kai, Lu Yinglin, Yu Debing, Shi Xiaoli, Du Wenxing, Yu Minli", "evidence": [ { "database": "RefSeq", "id": "NP_001035179", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001035179" } ], "reference": [ { "type": "PubMed", "id": "32050491", "url": "https://glygen.org/publication/PubMed/32050491" } ] } ], "pathway": [ { "id": "gga:422165", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422165", "resource": "KEGG Pathway" }, { "id": "R-GGA-3371497", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3371497", "resource": "Reactome", "description": "HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand" }, { "id": "R-GGA-383280", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-383280", "resource": "Reactome", "description": "Nuclear Receptor transcription pathway" }, { "id": "R-GGA-4090294", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4090294", "resource": "Reactome", "description": "SUMOylation of intracellular receptors" }, { "id": "R-GGA-5689880", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5689880", "resource": "Reactome", "description": "Ub-specific processing proteases" }, { "id": "R-GGA-8940973", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8940973", "resource": "Reactome", "description": "RUNX2 regulates osteoblast differentiation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1M5F4-1", "protein_name": "Androgen receptor", "gene_name": "AR", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MEVQLGLGRVYPRPPSKTYRGAFQNLFQSVCEVIQNPLPRHPEASSAAPSGARLQQQQETSPRQQQQQQQQREDGSPQVQSRGPTGYLALEEEQQPSQHHSAPEGHPESGCVPEPRAASAAGKGLQQPPPAPLDEDDSAAPSTLSLLGPTFPGLSSCSTDLKDILSEAGTMQLLQQQQQQQQEAVSEGSSGRAREATGAPISSKDSYLGGSSTISDSAKELCKAVSVSMGLGVEALEHLSPGEQLRGDCMYAPLLGPPAAVRPTPCAPLAECKGSLLDDGPSKGTEETAEYSPFKAGYTKGLDTESLSCSGSGEAGGSGTLELPSTLSLYKSGALDEVAAYQTRDYYNFPLALAGPPPPPPPPHPHARIKLENPLDYGSAWVAAAAQCRYGDLASLHGGGAAGPGSGSPSAAASSSWHTLFTAEEGQLYGPAVCGGGGGGSAGEAGAVAPYGYTRPPQGLAGQEGDFSPPDVWYPGGVVSRVPYPSPSCVKSEMGPWMENYSGPYGDMRLETTRDHVLPIDYYFPPQKTCLICGDEASGCHYGALTCGSCKVFFKRAAEGKQKYLCASRNDCTIDKFRRKNCPSCRLRKCYEAGMTLGARKLKKLGNLKLQEEGEASSATSPTEEPAQKLTVSHIEGYECQPIFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKWAKALPGFRNLHVDDQMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLVFNEYRMHKSRMYSQCVRMRHLSQEFGWLQITPQEFLCMKALLLFSIIPVDGLKNQKFFDELRMNYIKELDRIIACKRKNPTSCSRRFYQLTKLLDSVQPIARELHQFTFDLLIKSHMVSVDFPEMMAEIISVQVPKILSGKVKPIYFHTQ", "length": 890 }, "evidence": [ { "id": "A0A1D5P088", "url": "https://omabrowser.org/oma/group/A0A1D5P088/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P10275-1", "protein_name": "Androgen receptor", "gene_name": "AR", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEVQLGLGRVYPRPPSKTYRGAFQNLFQSVREVIQNPGPRHPEAASAAPPGASLLLLQQQQQQQQQQQQQQQQQQQQQQQETSPRQQQQQQGEDGSPQAHRRGPTGYLVLDEEQQPSQPQSALECHPERGCVPEPGAAVAASKGLPQQLPAPPDEDDSAAPSTLSLLGPTFPGLSSCSADLKDILSEASTMQLLQQQQQEAVSEGSSSGRAREASGAPTSSKDNYLGGTSTISDNAKELCKAVSVSMGLGVEALEHLSPGEQLRGDCMYAPLLGVPPAVRPTPCAPLAECKGSLLDDSAGKSTEDTAEYSPFKGGYTKGLEGESLGCSGSAAAGSSGTLELPSTLSLYKSGALDEAAAYQSRDYYNFPLALAGPPPPPPPPHPHARIKLENPLDYGSAWAAAAAQCRYGDLASLHGAGAAGPGSGSPSAAASSSWHTLFTAEEGQLYGPCGGGGGGGGGGGGGGGGGGGGGGGEAGAVAPYGYTRPPQGLAGQESDFTAPDVWYPGGMVSRVPYPSPTCVKSEMGPWMDSYSGPYGDMRLETARDHVLPIDYYFPPQKTCLICGDEASGCHYGALTCGSCKVFFKRAAEGKQKYLCASRNDCTIDKFRRKNCPSCRLRKCYEAGMTLGARKLKKLGNLKLQEEGEASSTTSPTEETTQKLTVSHIEGYECQPIFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKWAKALPGFRNLHVDDQMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLVFNEYRMHKSRMYSQCVRMRHLSQEFGWLQITPQEFLCMKALLLFSIIPVDGLKNQKFFDELRMNYIKELDRIIACKRKNPTSCSRRFYQLTKLLDSVQPIARELHQFTFDLLIKSHMVSVDFPEMMAEIISVQVPKILSGKVKPIYFHTQ", "length": 920 }, "evidence": [ { "id": "A0A1D5P088", "url": "https://omabrowser.org/oma/group/A0A1D5P088/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P19091-1", "protein_name": "Androgen receptor", "gene_name": "Ar", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": 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"http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45882:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00046", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00046", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03826", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03826", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_990341", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990341", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5P150", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P150", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5P150-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P150-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5P1S6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1S6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5P1S6-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1S6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSCMKDPLSLERLGAGNNKLCSSSPSSSSSSSSCHHQQPALAMATALAPGQARSSLEAAKHRLEVHTISDTSSPEAAEKEKSQQGKSEDAGPEDPSKKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERNQQAELCKNGFGPQFNGLMQPYDDMYPGYSYNNWAAKGLTSASLSTKSFPFFNSMNVNPLSSQSMFSPPNSISSMSMSSSMVPSAVTGVPGSGLNSLNNLNNLSNPSLNSAVPTPACPYAPPTPPYVYRDTCNSSLASLRLKAKQHSSFGYASVQNPASNLSACQYAVDRPV", "length": 333, "header": "tr|A0A1D5P1S6-1|A0A1D5P1S6_CHICK Isoform 1 of Homeobox protein OS=Gallus gallus OX=9031 GN=PITX2 PE=3 SV=2 CANONICAL=A0A1D5P1S6-1" }, "isoforms": [ { "isoform_ac": "A0A1D5P150-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1S6/entry#A0A1D5P150-1", "sequence": { "sequence": "MESNCRKLVSACVQLEKEKSQQGKSEDAGPEDPSKKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERNQQAELCKNGFGPQFNGLMQPYDDMYPGYSYNNWAAKGLTSASLSTKSFPFFNSMNVNPLSSQSMFSPPNSISSMSMSSSMVPSAVTGVPGSGLNSLNNLNNLSNPSLNSAVPTPACPYAPPTPPYVYRDTCNSSLASLRLKAKQHSSFGYASVQNPASNLSACQYAVDRPV", "length": 271, "header": "tr|A0A1D5P150-1|A0A1D5P1S6_CHICK Computationally mapped isoform of Homeobox protein OS=Gallus gallus OX=9031 GN=PITX2 PE=3 SV=2 CANONICAL=A0A1D5P1S6-1" }, "locus": { "chromosome": "4", "start_pos": 57316083, "end_pos": 57307757, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010008640.1", "url": "https://www.ensembl.org/id/ENSGALT00010008640.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010005059.1", "url": "https://www.ensembl.org/id/ENSGALP00010005059.1" } ] } }, { "isoform_ac": "A0A1D5P1S6-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1S6/entry#A0A1D5P1S6-1", "sequence": { "sequence": "MSCMKDPLSLERLGAGNNKLCSSSPSSSSSSSSCHHQQPALAMATALAPGQARSSLEAAKHRLEVHTISDTSSPEAAEKEKSQQGKSEDAGPEDPSKKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERNQQAELCKNGFGPQFNGLMQPYDDMYPGYSYNNWAAKGLTSASLSTKSFPFFNSMNVNPLSSQSMFSPPNSISSMSMSSSMVPSAVTGVPGSGLNSLNNLNNLSNPSLNSAVPTPACPYAPPTPPYVYRDTCNSSLASLRLKAKQHSSFGYASVQNPASNLSACQYAVDRPV", "length": 333, "header": "tr|A0A1D5P1S6-1|A0A1D5P1S6_CHICK Isoform 1 of Homeobox protein OS=Gallus gallus OX=9031 GN=PITX2 PE=3 SV=2 CANONICAL=A0A1D5P1S6-1" }, "locus": { "chromosome": "4", "start_pos": 57316083, "end_pos": 57312747, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010008638.1", "url": "https://www.ensembl.org/id/ENSGALT00010008638.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010005058.1", "url": "https://www.ensembl.org/id/ENSGALP00010005058.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 275, "start_aa": "Thr", "end_pos": 275, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr275", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 284, "start_aa": "Thr", "end_pos": 284, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr284", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:395862", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395862", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1UZS4-1", "protein_name": "Homeobox protein", "gene_name": "PITX2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MNCMKGPLHLEHRAAGTKLLAVSSSSSSCHHPQPLAMASVLAPGQTRSLDSSKHRLEVHTISDTSSPEAAEKDKSQQGKNEDVGAEDPSKKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERNQQAELCKNGFGPQFNGLMQPYDDMYPGYSYNNWAAKGLTSASLSTKSFPFFNSMNVNPLSSQSMFSPPNSISSMSMSSSMVPSAVTGVPGSSLNSLNNLNNLSSPSLNSAVPTPACPYAPPTPPYVYRDTCNSSLASLRLKAKQHSSFGYASVQNPASNLSACQYAVDRPV", "length": 326 }, "evidence": [ { "id": "A0A1D5P1S6", "url": "https://omabrowser.org/oma/group/A0A1D5P1S6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P97474-1", "protein_name": "Pituitary homeobox 2", "gene_name": "Pitx2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "METNCRKLVSACVQLGVQPAAVECLFSKDSEIKKVEFTDSPKSRKESASSKLFPRQHPGANEKDKGQQGKNEDVGAEDPSKKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERNQQAELCKNGFGPQFNGLMQPYDDMYPGYSYNNWAAKGLTSASLSTKSFPFFNSMNVNPLSSQSMFSPPNSISSMSMSSSMVPSAVTGVPGSSLNSLNNLNNLSSPSLNSAVPTPACPYAPPTPPYVYRDTCNSSLASLRLKAKQHSSFGYASVQNPASNLSACQYAVDRPV", "length": 317 }, "evidence": [ { "id": "A0A1D5P1S6", "url": "https://omabrowser.org/oma/group/A0A1D5P1S6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q99697-1", "protein_name": "Pituitary homeobox 2", "gene_name": "PITX2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METNCRKLVSACVQLGVQPAAVECLFSKDSEIKKVEFTDSPESRKEAASSKFFPRQHPGANEKDKSQQGKNEDVGAEDPSKKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERNQQAELCKNGFGPQFNGLMQPYDDMYPGYSYNNWAAKGLTSASLSTKSFPFFNSMNVNPLSSQSMFSPPNSISSMSMSSSMVPSAVTGVPGSSLNSLNNLNNLSSPSLNSAVPTPACPYAPPTPPYVYRDTCNSSLASLRLKAKQHSSFGYASVQNPASNLSACQYAVDRPV", "length": 317 }, "evidence": [ { "id": "A0A1D5P1S6", "url": "https://omabrowser.org/oma/group/A0A1D5P1S6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9R0W1-1", "protein_name": "Pituitary homeobox 2", "gene_name": "Pitx2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNCMKGPLPLEHRAAGTKLSAASSPFCHHTQALAMASVLAPGQPRSLDASKHRLEVHTISDTSSPEVAEKDKGQQGKNEDVGAEDPSKKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERNQQAELCKNGFGPQFNGLMQPYDDMYPGYSYNNWAAKGLTSASLSTKSFPFFNSMNVNPLSSQSMFSPPNSISSMSMSSSMVPSAVTGVPGSSLNSLNNLNNLSSPSLNSAVPTPACPYAPPTPPYVYRDTCNSSLASLRLKAKQHSSFGYASVQNPASNLSACQYAVDRPV", "length": 324 }, "evidence": [ { "id": "A0A1D5P1S6", "url": "https://omabrowser.org/oma/group/A0A1D5P1S6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9W5Z2-1", "protein_name": "Pituitary homeobox 2", "gene_name": "pitx2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTSMKDPLSLDHHHHNHHVTGSKHAPLSMASSLQPLQRSVDSKHRLDVHTVSDTSSPESVEKEKGQSKNEDSNDDPSKKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERNQQAELCKNGFGPQFNGLMQPYDDMYPSYTYNNWAAKGLTSASLSTKSFPFFNSMNVNPLSSQTMFSPPNSISSMSMSSSMVPSAVTGVPGSSLNSLNNLNNLSNPSLNSGVPTPACPYAPPTPPYVYRDTCNSSLASLRLKAKQHSSFGYASVQNPASNLSACQYAVDRPV", "length": 314 }, "evidence": [ { "id": "A0A1D5P1S6", "url": "https://omabrowser.org/oma/group/A0A1D5P1S6/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "system development", "id": "GO:0048731", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048731", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P1S6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1S6" } ], "pmid": "" }, { "name": "animal organ morphogenesis", "id": "GO:0009887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009887", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P1S6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1S6" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P1S6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1S6" } ], "pmid": "" }, { "name": "anatomical structure morphogenesis", "id": "GO:0009653", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009653", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P1S6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1S6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P1S6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1S6" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P1S6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1S6" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P1S6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1S6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P1S6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1S6" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P1S6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1S6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 139, "end_pos": 141, "annotation": "n_glycosylation_sequon" }, { "start_pos": 263, "end_pos": 265, "annotation": "n_glycosylation_sequon" }, { "start_pos": 294, "end_pos": 296, "annotation": "n_glycosylation_sequon" }, { "start_pos": 321, "end_pos": 323, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5P1S6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 333, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5P1S6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5P1S6" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A1D5P1S6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1S6" }, { "id": "PRU00108", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00108" } ], "ann_type": "Nucleotide_Binding_Annotation", "uniprotkb_annotation": "Homeobox", "eco_id": "ECO_0000256", "start_pos": 101, "end_pos": 160, "start_aa": "Gln", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 275, 284 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 139, "end_pos": 141 }, { "start_pos": 263, "end_pos": 265 }, { "start_pos": 294, "end_pos": 296 }, { "start_pos": 321, "end_pos": 323 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A1D5P1G4-1", "uniprot_ac": "A0A1D5P1G4", "uniprot_id": "A0A1D5P1G4_CHICK", "mass": { "chemical_mass": 40629.0, "monoisotopic_mass": 40629.0 }, "refseq": { "ac": "XP_015132813", "name": "POU domain, class 4, transcription factor 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015132813" }, "gene_names": [ { "name": "POU4F1", "type": "recommended", "evidence": [ { "id": "A0A1D5P1G4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1G4" } ] }, { "name": "POU4F1", "type": "synonym", "evidence": [ { "id": "XP_015132813", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015132813" } ] } ], "protein_names": [ { "name": "POU domain protein", "type": "recommended", "evidence": [ { "id": "A0A1D5P1G4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1G4/entry#names_and_taxonomy" } ] }, { "name": "POU domain, class 4, transcription factor 1", "type": "synonym", "evidence": [ { "id": "XP_015132813", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015132813" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015132813", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015132813" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P1G4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1G4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "POU4F1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1G4", "locus": { "chromosome": "1", "start_pos": 153491621, "end_pos": 153489663, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010000726", "url": "https://www.ensembl.org/id/ENSGALG00010000726" } ] } } ], "crossref": [ { "id": "A0A1D5P1G4", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5P1G4", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00086", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00086", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100857623", "url": "https://www.ncbi.nlm.nih.gov/gene/100857623", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000327", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000327", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001356", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001356", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010982", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010982", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013847", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013847", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017970", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017970", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050255", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050255", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:100857623", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100857623", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "AHSHMHG", "url": "https://omabrowser.org/oma/group/AHSHMHG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5P1G4", "url": "https://www.orthodb.org/?gene=A0A1D5P1G4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11636", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11636", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11636:SF42", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11636:SF42", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00046", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00046", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00157", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00157", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015132813", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015132813", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5P1G4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1G4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5P1G4-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1G4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMSMNSKQPHFAMHPTLPEHKYPSLHSSSEAIRRACLPTPPLQSNLFASLDETLLARAEALAAVDIAVSQGKSHPFKPDATYHTMNSVPCTSTSTVPLAHHHHHHHHHHQALEPGDLLEHITSPSLALMPGGAGGGGGGGGHDGAGGGGGGGGGGGGGGGGGGGGGGLISSSAHPHPHMHGLGHLSHPAAMNMPSGLPHPGLVAAHHGAAGQVASAAAVVGAAGLASICDSDTDPRELEAFAERFKQRRIKLGVTQADVGSALANLKIPGVGSLSQSTICRFESLTLSHNNMIALKPILQAWLEEAEGAQREKMNKPELFNGGEKKRKRTSIAAPEKRSLEAYFAVQPRPSSEKIAAIAEKLDLKKNVVRVWFCNQRQKQKRMKFSATY", "length": 389, "header": "tr|A0A1D5P1G4-1|A0A1D5P1G4_CHICK Isoform 1 of POU domain protein OS=Gallus gallus OX=9031 GN=POU4F1 PE=3 SV=1 CANONICAL=A0A1D5P1G4-1" }, "isoforms": [ { "isoform_ac": "A0A1D5P1G4-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1G4/entry#A0A1D5P1G4-1", "sequence": { "sequence": "MMSMNSKQPHFAMHPTLPEHKYPSLHSSSEAIRRACLPTPPLQSNLFASLDETLLARAEALAAVDIAVSQGKSHPFKPDATYHTMNSVPCTSTSTVPLAHHHHHHHHHHQALEPGDLLEHITSPSLALMPGGAGGGGGGGGHDGAGGGGGGGGGGGGGGGGGGGGGGLISSSAHPHPHMHGLGHLSHPAAMNMPSGLPHPGLVAAHHGAAGQVASAAAVVGAAGLASICDSDTDPRELEAFAERFKQRRIKLGVTQADVGSALANLKIPGVGSLSQSTICRFESLTLSHNNMIALKPILQAWLEEAEGAQREKMNKPELFNGGEKKRKRTSIAAPEKRSLEAYFAVQPRPSSEKIAAIAEKLDLKKNVVRVWFCNQRQKQKRMKFSATY", "length": 389, "header": "tr|A0A1D5P1G4-1|A0A1D5P1G4_CHICK Isoform 1 of POU domain protein OS=Gallus gallus OX=9031 GN=POU4F1 PE=3 SV=1 CANONICAL=A0A1D5P1G4-1" }, "locus": { "chromosome": "1", "start_pos": 153491618, "end_pos": 153489813, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010001554.1", "url": "https://www.ensembl.org/id/ENSGALT00010001554.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010000860.1", "url": "https://www.ensembl.org/id/ENSGALP00010000860.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 39, "start_aa": "Thr", "end_pos": 39, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr39", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:100857623", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100857623", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287B9Y5-1", "protein_name": "POU domain protein", "gene_name": "POU4F1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MMSMNSKQPHFAMHPTLPEHKYPSLHSSSEAIRRACLPTPPLQSNLFASLDETLLARAEALAAVDIAVSQGKSHPFKPDATYHTMNSVPCTSTSTVPLAHHHHHHHHHQALEPGDLLDHISSPSLALMAGAGGAGAAGGGGSAHDGPGGGGGPGGGGGPGGGGPGGGGGGGGPGGGGGGPGGGLLGGSAHPHPHMHGLGHLSHPAAAAAMNMPSGLPHPGLVAAAAHHGAAAAAAAAAAGQVAAASAAAAVVGAAGLASICDSDTDPRELEAFAERFKQRRIKLGVTQADVGSALANLKIPGVGSLSQSTICRFESLTLSHNNMIALKPILQAWLEEAEGAQREKMNKPELFNGGEKKRKRTSIAAPEKRSLEAYFAVQPRPSSEKIAAIAEKLDLKKNVVRVWFCNQRQKQKRMKFSATY", "length": 421 }, "evidence": [ { "id": "A0A1D5P1G4", "url": "https://omabrowser.org/oma/group/A0A1D5P1G4/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A3Q1MTW2-1", "protein_name": "POU domain protein", "gene_name": "POU4F1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MMSMNSKQPHFAMHPTLPEHKYPSLHSSSEAIRRACLPTPPLQSNLFASLDETLLARAEALAAVDIAVSQGKSHPFKPDATYHTMNSVPCTSTSTVPLAHHHHHHHHHQALEPGDLLDHISSPSLALMAGAGGASAAGGGAHDGPGGGGPGGGGGGGPGGGGGGPGGGGGGGPGGGGGGPGGGLLGGSAHPHPHMHGLGHLSHPAAAAAMNMPSGLPHPGLVAAAAHHGAAAAAAAAAAGQVAAASAAAAVVGAAGLASICDSDTDPRELEAFAERFKQRRIKLGVTQADVGSALANLKIPGVGSLSQSTICRFESLTLSHNNMIALKPILQAWLEEAEGAQREKMNKPELFNGGEKKRKRTSIAAPEKRSLEAYFAVQPRPSSEKIAAIAEKLDLKKNVVRVWFCNQRQKQKRMKFSATY", "length": 421 }, "evidence": [ { "id": "A0A1D5P1G4", "url": "https://omabrowser.org/oma/group/A0A1D5P1G4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P17208-1", "protein_name": "POU domain, class 4, transcription factor 1", "gene_name": "Pou4f1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMSMNSKQPHFAMHPTLPEHKYPSLHSSSEAIRRACLPTPPLQSNLFASLDETLLARAEALAAVDIAVSQGKSHPFKPDATYHTMNSVPCTSTSTVPLAHHHHHHHHHQALEPGDLLDHISSPSLALMAGAGGAGAAGGGGGAHDGPGGGGGPGGGGGPGGGGPGGGGGGGGPGGGGGGPGGGLLGGSAHPHPHMHGLGHLSHPAAAAAMNMPSGLPHPGLVAAAAHHGAAAAAAAAAAGQVAAASAAAAVVGAAGLASICDSDTDPRELEAFAERFKQRRIKLGVTQADVGSALANLKIPGVGSLSQSTICRFESLTLSHNNMIALKPILQAWLEEAEGAQREKMNKPELFNGGEKKRKRTSIAAPEKRSLEAYFAVQPRPSSEKIAAIAEKLDLKKNVVRVWFCNQRQKQKRMKFSATY", "length": 421 }, "evidence": [ { "id": "A0A1D5P1G4", "url": "https://omabrowser.org/oma/group/A0A1D5P1G4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q01851-1", "protein_name": "POU domain, class 4, transcription factor 1", "gene_name": "POU4F1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MMSMNSKQPHFAMHPTLPEHKYPSLHSSSEAIRRACLPTPPLQSNLFASLDETLLARAEALAAVDIAVSQGKSHPFKPDATYHTMNSVPCTSTSTVPLAHHHHHHHHHQALEPGDLLDHISSPSLALMAGAGGAGAAAGGGGAHDGPGGGGGPGGGGGPGGGPGGGGGGGPGGGGGGPGGGLLGGSAHPHPHMHSLGHLSHPAAAAAMNMPSGLPHPGLVAAAAHHGAAAAAAAAAAGQVAAASAAAAVVGAAGLASICDSDTDPRELEAFAERFKQRRIKLGVTQADVGSALANLKIPGVGSLSQSTICRFESLTLSHNNMIALKPILQAWLEEAEGAQREKMNKPELFNGGEKKRKRTSIAAPEKRSLEAYFAVQPRPSSEKIAAIAEKLDLKKNVVRVWFCNQRQKQKRMKFSATY", "length": 419 }, "evidence": [ { "id": "A0A1D5P1G4", "url": "https://omabrowser.org/oma/group/A0A1D5P1G4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 16, "go_terms": [ { "name": "sensory system development", "id": "GO:0048880", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048880", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P1G4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1G4" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P1G4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1G4" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P1G4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1G4" } ], "pmid": "" }, { "name": "positive regulation of gene expression", "id": "GO:0010628", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010628", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P1G4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1G4" } ], "pmid": "" }, { "name": "negative regulation of gene expression", "id": "GO:0010629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010629", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P1G4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1G4" } ], "pmid": "" }, { "name": "neuron projection development", "id": "GO:0031175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031175", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P1G4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1G4" } ], "pmid": "" }, { "name": "negative regulation of neuron apoptotic process", "id": "GO:0043524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043524", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P1G4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1G4" } ], "pmid": "" }, { "name": "trigeminal nerve development", "id": "GO:0021559", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021559", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P1G4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1G4" } ], "pmid": "" }, { "name": "intrinsic apoptotic signaling pathway by p53 class mediator", "id": "GO:0072332", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072332", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P1G4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1G4" } ], "pmid": "" }, { "name": "cellular response to cytokine stimulus", "id": "GO:0071345", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071345", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P1G4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1G4" } ], "pmid": "" }, { "name": "cellular response to estradiol stimulus", "id": "GO:0071392", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071392", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P1G4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1G4" } ], "pmid": "" }, { "name": "neuron fate specification", "id": "GO:0048665", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048665", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P1G4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1G4" } ], "pmid": "" }, { "name": "regulation of cell cycle", "id": "GO:0051726", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051726", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P1G4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1G4" } ], "pmid": "" }, { "name": "positive regulation of osteoclast differentiation", "id": "GO:0045672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045672", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P1G4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1G4" } ], "pmid": "" }, { "name": "ventricular compact myocardium morphogenesis", "id": "GO:0003223", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003223", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P1G4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1G4" } ], "pmid": "" }, { "name": "peripheral nervous system neuron development", "id": "GO:0048935", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048935", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P1G4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1G4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 8, "go_terms": [ { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P1G4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1G4" } ], "pmid": "" }, { "name": "GTPase binding", "id": "GO:0051020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051020", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P1G4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1G4" } ], "pmid": "" }, { "name": "DNA-binding transcription repressor activity, RNA polymerase II-specific", "id": "GO:0001227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001227", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P1G4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1G4" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P1G4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1G4" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P1G4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1G4" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P1G4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1G4" } ], "pmid": "" }, { "name": "single-stranded DNA binding", "id": "GO:0003697", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003697", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P1G4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1G4" } ], "pmid": "" }, { "name": "RNA polymerase II-specific DNA-binding transcription factor binding", "id": "GO:0061629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061629", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P1G4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1G4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P1G4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1G4" } ], "pmid": "" }, { "name": "neuron projection", "id": "GO:0043005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043005", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P1G4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1G4" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P1G4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1G4" } ], "pmid": "" }, { "name": "RNA polymerase 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"https://prosite.expasy.org/PRU00108" } ], "ann_type": "Nucleotide_Binding_Annotation", "uniprotkb_annotation": "Homeobox", "eco_id": "ECO_0000256", "start_pos": 325, "end_pos": 384, "start_aa": "Lys", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 39 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A1D5P2P1-1", "uniprot_ac": "A0A1D5P2P1", "uniprot_id": "A0A1D5P2P1_CHICK", "mass": { "chemical_mass": 38296.0, "monoisotopic_mass": 38296.0 }, "refseq": { "ac": "NP_990599", "name": "CCN family member 3 precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990599" }, "gene_names": [ { "name": "CCN3", "type": "recommended", "evidence": [ { "id": "A0A1D5P2P1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P2P1" } ] }, { "name": "CCN3", "type": "synonym", "evidence": [ { "id": "NP_990599", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990599" } ] }, { "name": "NOV", "type": "synonym", "evidence": [ { "id": "NP_990599", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990599" } ] } ], "protein_names": [ { "name": "CCN family member 3", "type": "recommended", "evidence": [ { "id": "A0A1D5P2P1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P2P1/entry#names_and_taxonomy" } ] }, { "name": "CCN family member 3 precursor", "type": "synonym", "evidence": [ { "id": "NP_990599", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990599" } ] }, { "name": "CCN family member 3", "type": "synonym", "evidence": [ { "id": "NP_990599", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990599" } ] }, { "name": "Cellular communication network factor 3", "type": "synonym", "evidence": [ { "id": "A0A1D5P2P1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P2P1/entry#names_and_taxonomy" } ] }, { "name": "Nephroblastoma-overexpressed gene protein", "type": "synonym", "evidence": [ { "id": "A0A1D5P2P1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P2P1/entry#names_and_taxonomy" } ] }, { "name": "Protein NOV", "type": "synonym", "evidence": [ { "id": "A0A1D5P2P1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P2P1/entry#names_and_taxonomy" } ] }, { "name": "nephroblastoma overexpressed", "type": "synonym", "evidence": [ { "id": "NP_990599", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990599" } ] }, { "name": "nephroblastoma-overexpressed gene protein", "type": "synonym", "evidence": [ { "id": "NP_990599", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990599" } ] }, { "name": "protein NOV", "type": "synonym", "evidence": [ { "id": "NP_990599", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990599" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: X59284.1, SRR13267649.108912.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3109051, SAMN02738215 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000044.1. On Sep 23, 2021 this sequence version replaced NP_990599.1.", "evidence": [ { "database": "RefSeq", "id": "NP_990599", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990599" } ] }, { "annotation": "Results establish the expression pattern of CCN3 in the developing retina, and show CCN3 expression is induced by activated BMP signaling, whereas Notch signaling decreases CCN3 mRNA and protein levels in Muller cells and has no effect in retinal neurons. Erratum:[Dev Neurobiol. 2013 Mar;73(3):257. Maryvonne, Laurent [corrected to Laurent, Maryvonne]; Gwenvael, Le Dreau [corrected to Le Dreau, Gwenvael]; Xavier, Guillonneau [corrected to Guillonneau, Xavier]; Cecile, Lelievre Elise [corrected to Lelievre, Elise]; Amelie, Slembrouck [corrected]", "evidence": [ { "database": "RefSeq", "id": "NP_990599", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990599" }, { "database": "PubMed", "id": "22038708", "url": "https://glygen.org/publication/PubMed/22038708" } ] }, { "annotation": "The expression of NOV was intense in the developing tendons and in the developing joints, whereas the chondrogenic blastemas were negative for NOV transcripts. NOV induced intense upregulation of Tenascin C and, at a reduced level, of alpha 5 Integrin, Sox9, and Activin beta-A.", "evidence": [ { "database": "RefSeq", "id": "NP_990599", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990599" }, { "database": "PubMed", "id": "21931747", "url": "https://glygen.org/publication/PubMed/21931747" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P2P1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P2P1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CCN3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P2P1", "locus": { "chromosome": "2", "start_pos": 135490973, "end_pos": 135485255, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010009284", "url": "https://www.ensembl.org/id/ENSGALG00010009284" } ] } } ], "crossref": [ { "id": "A0A1D5P2P1", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5P2P1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000038364", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000038364", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "396204", "url": "https://www.ncbi.nlm.nih.gov/gene/396204", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000867", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000867", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000884", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000884", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001007", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001007", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006207", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006207", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006208", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006208", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009030", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009030", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012395", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012395", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017891", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017891", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036383", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036383", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043973", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043973", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050941", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050941", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:396204", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:396204", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PRCNHDL", "url": "https://omabrowser.org/oma/group/PRCNHDL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5P2P1", "url": "https://www.orthodb.org/?gene=A0A1D5P2P1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XWP1", "url": "https://www.orthodb.org/?gene=A0A8V0XWP1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11348", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11348", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11348:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11348:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00007", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00007", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00093", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00093", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00219", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00219", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19035", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19035", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_990599", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990599", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5P2P1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P2P1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5P2P1-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P2P1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XWP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XWP1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XWP1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XWP1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "METGGGQGLPVLLLLLLLLRPCEVSGREAACPRPCGGRCPAEPPRCAPGVPAVLDGCGCCLVCARQRGESCSPLLPCDESGGLYCDRGPEDGGGAGICMVLEGDNCVFDGMIYRNGETFQPSCKYQCTCRDGQIGCLPRCNLGLLLPGPDCPFPRKIEVPGECCEKWVCDPRDEVLLGGFAMAAYRQEATLGIDVSDSSANCIEQTTEWSACSKSCGMGFSTRVTNRNQQCEMVKQTRLCMMRPCENEEPSDKKGKKCIRTKKSMKAVRFEYKNCTSVQTYKPRYCGLCNDGRCCTPHNTKTIQVEFRCPQGKFLKKPMMLINTCVCHGNCPQSNNAFFQPLDPMSSEAKI", "length": 351, "header": "tr|A0A1D5P2P1-1|A0A1D5P2P1_CHICK Isoform 1 of CCN family member 3 OS=Gallus gallus OX=9031 GN=CCN3 PE=3 SV=1 CANONICAL=A0A1D5P2P1-1" }, "isoforms": [ { "isoform_ac": "A0A1D5P2P1-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P2P1/entry#A0A1D5P2P1-1", "sequence": { "sequence": "METGGGQGLPVLLLLLLLLRPCEVSGREAACPRPCGGRCPAEPPRCAPGVPAVLDGCGCCLVCARQRGESCSPLLPCDESGGLYCDRGPEDGGGAGICMVLEGDNCVFDGMIYRNGETFQPSCKYQCTCRDGQIGCLPRCNLGLLLPGPDCPFPRKIEVPGECCEKWVCDPRDEVLLGGFAMAAYRQEATLGIDVSDSSANCIEQTTEWSACSKSCGMGFSTRVTNRNQQCEMVKQTRLCMMRPCENEEPSDKKGKKCIRTKKSMKAVRFEYKNCTSVQTYKPRYCGLCNDGRCCTPHNTKTIQVEFRCPQGKFLKKPMMLINTCVCHGNCPQSNNAFFQPLDPMSSEAKI", "length": 351, "header": "tr|A0A1D5P2P1-1|A0A1D5P2P1_CHICK Isoform 1 of CCN family member 3 OS=Gallus gallus OX=9031 GN=CCN3 PE=3 SV=1 CANONICAL=A0A1D5P2P1-1" }, "locus": { "chromosome": "2", "start_pos": 135490083, "end_pos": 135485702, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010022108.1", "url": "https://www.ensembl.org/id/ENSGALT00010022108.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010012681.1", "url": "https://www.ensembl.org/id/ENSGALP00010012681.1" } ] } }, { "isoform_ac": "A0A8V0XWP1-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P2P1/entry#A0A8V0XWP1-1", "sequence": { "sequence": "MVSGREAACPRPCGGRCPAEPPRCAPGVPAVLDGCGCCLVCARQRGESCSPLLPCDESGGLYCDRGPEDGGGAGICMVLEGDNCVFDGMIYRNGETFQPSCKYQCTCRDGQIGCLPRCNLGLLLPGPDCPFPRKIEVPGECCEKWVCDPRDEVLLGGFAMAAYRQEATLGIDVSDSSANCIEQTTEWSACSKSCGMGFSTRVTNRNQQCEMVKQTRLCMMRPCENEEPSDKKGKKCIRTKKSMKAVRFEYKNCTSVQTYKPRYCGLCNDGRCCTPHNTKTIQVEFRCPQGKFLKKPMMLINTCVCHGNCPQSNNAFFQPLDPMSSEAKI", "length": 329, "header": "tr|A0A8V0XWP1-1|A0A8V0XWP1_CHICK Computationally mapped isoform of CCN family member 3 OS=Gallus gallus OX=9031 GN=CCN3 PE=3 SV=1 CANONICAL=A0A1D5P2P1-1" }, "locus": { "chromosome": "2", "start_pos": 135490083, "end_pos": 135485332, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010022109.1", "url": "https://www.ensembl.org/id/ENSGALT00010022109.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010012682.1", "url": "https://www.ensembl.org/id/ENSGALP00010012682.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Defining the earliest transcriptional steps of chondrogenic progenitor specification during the formation of the digits in the embryonic limb.", "journal": "PloS one", "date": "2011", "authors": "Lorda-Diez Carlos I, Montero Juan A, Diaz-Mendoza Manuel J, Garcia-Porrero Juan A, Hurle Juan M", "evidence": [ { "database": "RefSeq", "id": "NP_990599", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990599" } ], "reference": [ { "type": "PubMed", "id": "21931747", "url": "https://glygen.org/publication/PubMed/21931747" } ] }, { "title": "Temporal and spatial expression of CCN3 during retina development.", "journal": "Developmental neurobiology", "date": "2012-11", "authors": "Laurent Maryvonne, Maryvonne Laurent, Le Dr\u00e9au Gwenva\u00ebl, Gwenva\u00ebl Le Dr\u00e9au, Guillonneau Xavier, Xavier Guillonneau, Leli\u00e8vre Elise, C\u00e9cile Leli\u00e8vre Elise, Slembrouck Am\u00e9lie, Am\u00e9lie Slembrouck, Goureau Olivier, Olivier Goureau, Martinerie C\u00e9cile, C\u00e9cile Martinerie, Marx Maria, Maria Marx", "evidence": [ { "database": "RefSeq", "id": "NP_990599", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990599" } ], "reference": [ { "type": "PubMed", "id": "22038708", "url": "https://glygen.org/publication/PubMed/22038708" } ] } ], "pathway": [ { "id": "gga:396204", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:396204", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A481D0V4-1", "protein_name": "CCN family member 3", "gene_name": "CCN3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MQRAQSLRLGLPKRCLCLAFLLLHLLGQVAATQRCPPSCPAPCPKKPPTCAPGVRAVLDDCSCCLVCARQRGESCSVMLPCEESRGLFCDRRADPSAQTGICMAIEGDNCVFDGVIYQSGETFQPSCKYQCACQDGQVGCVPRCEEDLLLPQPDCPAPRKVKVPGECCEKWICDSNETGTLGDLQTLPAYRTEATVGVAISDSGTNCIEQTTEWSACSKSCGMGFSTRVTNRNPHCEMVKQTRLCLVRPCDQEHTQPTDKKGKKCLRTTKSLKAIHLQFENCTSLHTYRPRFCGVCSDGRCCTPHSTKTIRVQFRCSPGKTIQKPVMVIGTCTCHNNCPHNNASFLQDLKPNTSRGEM", "length": 358 }, "evidence": [ { "id": "A0A1D5P2P1", "url": "https://omabrowser.org/oma/group/A0A1D5P2P1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P48745-1", "protein_name": "CCN family member 3", "gene_name": "CCN3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQSVQSTSFCLRKQCLCLTFLLLHLLGQVAATQRCPPQCPGRCPATPPTCAPGVRAVLDGCSCCLVCARQRGESCSDLEPCDESSGLYCDRSADPSNQTGICTAVEGDNCVFDGVIYRSGEKFQPSCKFQCTCRDGQIGCVPRCQLDVLLPEPNCPAPRKVEVPGECCEKWICGPDEEDSLGGLTLAAYRPEATLGVEVSDSSVNCIEQTTEWTACSKSCGMGFSTRVTNRNRQCEMLKQTRLCMVRPCEQEPEQPTDKKGKKCLRTKKSLKAIHLQFKNCTSLHTYKPRFCGVCSDGRCCTPHNTKTIQAEFQCSPGQIVKKPVMVIGTCTCHTNCPKNNEAFLQELELKTTRGKM", "length": 357 }, "evidence": [ { "id": "A0A1D5P2P1", "url": "https://omabrowser.org/oma/group/A0A1D5P2P1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q64299-1", "protein_name": "CCN family member 3", "gene_name": "Ccn3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSLFLRKRCLCLGFLLFHLLSQVSASLRCPSRCPPKCPSISPTCAPGVRSVLDGCSCCPVCARQRGESCSEMRPCDQSSGLYCDRSADPNNQTGICMVPEGDNCVFDGVIYRNGEKFEPNCQYFCTCRDGQIGCLPRCQLDVLLPGPDCPAPRKVAVPGECCEKWTCGSDEQGTQGTLGGLALPAYRPEATVGVEVSDSSINCIEQTTEWSACSKSCGMGVSTRVTNRNRQCEMVKQTRLCIVRPCEQEPEEVTDKKGKKCLRTKKSLKAIHLQFENCTSLYTYKPRFCGVCSDGRCCTPHNTKTIQVEFQCLPGEIIKKPVMVIGTCTCYSNCPQNNEAFLQDLELKTSRGEI", "length": 354 }, "evidence": [ { "id": "A0A1D5P2P1", "url": "https://omabrowser.org/oma/group/A0A1D5P2P1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9QZQ5-1", "protein_name": "CCN family member 3", "gene_name": "Ccn3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSVFLRKQCLCLGFLLLHLLNQVSATLRCPSRCPSQCPSISPTCAPGVRSVLDGCSCCPVCARQRGESCSEMRPCDQSSGLYCDRSADPNNETGICMVPEGDNCVFDGVIYRNGEKFEPNCQYHCTCRDGQIGCVPRCQLDVLLPGPDCPAPKKVAVPGECCEKWTCGSEEKGTLGGLALPAYRPEATVGVELSDSSINCIEQTTEWSACSKSCGMGLSTRVTNRNLQCEMVKQTRLCMVRPCEQEPGEATDMKGKKCLRTKKSLKSIHLQFKNCTSLYTYKPRFCGICSDGRCCTPFNTKTIQVEFQCLPGQIIKKPVMVIGTCTCHSNCPQNNEAFLQELELKTSRGEM", "length": 351 }, "evidence": [ { "id": "A0A1D5P2P1", "url": "https://omabrowser.org/oma/group/A0A1D5P2P1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 25, "go_terms": [ { "name": "endothelial cell-cell adhesion", "id": "GO:0071603", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071603", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P2P1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P2P1" } ], "pmid": "" }, { "name": "negative regulation of monocyte chemotaxis", "id": "GO:0090027", "url": 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regulation of Notch signaling pathway", "id": "GO:0045747", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045747", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P2P1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P2P1" } ], "pmid": "" }, { "name": "negative regulation of insulin secretion", "id": "GO:0046676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046676", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P2P1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P2P1" } ], "pmid": "" }, { "name": "negative regulation of cell growth", "id": "GO:0030308", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030308", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P2P1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P2P1" } ], "pmid": "" }, { "name": "negative regulation of non-canonical NF-kappaB signal transduction", "id": "GO:1901223", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901223", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P2P1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P2P1" } ], "pmid": "" }, { "name": "chondrocyte differentiation", "id": "GO:0002062", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002062", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P2P1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P2P1" } ], "pmid": "" }, { "name": "smooth muscle cell proliferation", "id": "GO:0048659", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048659", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P2P1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P2P1" } ], "pmid": "" }, { "name": "negative regulation of myotube differentiation", "id": "GO:0010832", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010832", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P2P1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P2P1" } ], "pmid": "" }, { "name": "fibroblast migration", "id": "GO:0010761", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010761", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P2P1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P2P1" } ], "pmid": "" }, { "name": "endothelial cell chemotaxis", "id": "GO:0035767", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035767", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P2P1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P2P1" } ], "pmid": "" }, { "name": "type B pancreatic cell proliferation", "id": "GO:0044342", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044342", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P2P1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P2P1" } ], "pmid": "" }, { "name": "negative regulation of chondrocyte proliferation", "id": "GO:1902731", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902731", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P2P1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P2P1" } ], "pmid": "" }, { "name": "positive regulation of ossification", "id": "GO:0045778", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045778", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P2P1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P2P1" } ], "pmid": "" }, { "name": "hematopoietic stem cell homeostasis", "id": "GO:0061484", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061484", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P2P1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P2P1" } ], "pmid": "" }, { "name": "bone regeneration", "id": "GO:1990523", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990523", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P2P1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P2P1" } ], "pmid": "" }, { "name": "regulation of developmental process", "id": "GO:0050793", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050793", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P2P1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P2P1" } ], "pmid": "" }, { "name": "positive regulation of multicellular organismal process", "id": "GO:0051240", "url": 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"glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A1D5P395-1", "uniprot_ac": "A0A1D5P395", "uniprot_id": "A0A1D5P395_CHICK", "mass": { "chemical_mass": 94805.0, "monoisotopic_mass": 94805.0 }, "refseq": { "ac": "NP_990275", "name": "axin-1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990275" }, "gene_names": [ { "name": "AXIN1", "type": "recommended", "evidence": [ { "id": "A0A1D5P395", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P395" } ] }, { "name": "AXIN1-RGS", "type": "synonym", "evidence": [ { "id": "NP_990275", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990275" } ] }, { "name": "AXIN1", "type": "synonym", "evidence": [ { "id": "NP_990275", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990275" } ] }, { "name": "AXIN", "type": "synonym", "evidence": [ { "id": "NP_990275", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990275" } ] }, { "name": "axin-1", "type": "synonym", "evidence": [ { "id": "NP_990275", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990275" } ] } ], "protein_names": [ { "name": "Axin-1", "type": "recommended", "evidence": [ { "id": "A0A1D5P395", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P395/entry#names_and_taxonomy" } ] }, { "name": "Axis inhibition protein 1", "type": "synonym", "evidence": [ { "id": "A0A1D5P395", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P395/entry#names_and_taxonomy" } ] }, { "name": "axin-1", "type": "synonym", "evidence": [ { "id": "NP_990275", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990275" } ] }, { "name": "axis inhibition protein 1", "type": "synonym", "evidence": [ { "id": "NP_990275", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990275" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AF009012.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000257.1. On Sep 23, 2021 this sequence version replaced NP_990275.1.", "evidence": [ { "database": "RefSeq", "id": "NP_990275", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990275" } ] }, { "annotation": "Study identifies GSK3beta as a serine/threonine kinase participating in intracellular signaling of Sema3A that induces acceleration of axonal transport", "evidence": [ { "database": "RefSeq", "id": "NP_990275", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990275" }, { "database": "PubMed", "id": "25528666", "url": "https://glygen.org/publication/PubMed/25528666" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P395", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P395" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "AXIN1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P395", "locus": { "chromosome": "14", "start_pos": 12235937, "end_pos": 12167177, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010016911", "url": "https://www.ensembl.org/id/ENSGALG00010016911" } ] } } ], "crossref": [ { "id": "A0A1D5P395", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5P395", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000029402", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000029402", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd08707", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08707", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd11582", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11582", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "395786", "url": "https://www.ncbi.nlm.nih.gov/gene/395786", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001158", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001158", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014936", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014936", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016137", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016137", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024066", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024066", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029071", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029071", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032101", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032101", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036305", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036305", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038207", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038207", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043581", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043581", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044926", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044926", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:395786", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395786", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YVYTAST", "url": "https://omabrowser.org/oma/group/YVYTAST/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5P395", "url": "https://www.orthodb.org/?gene=A0A1D5P395", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z054", "url": 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"categories": [ "Protein Classification", "Other" ] }, { "id": "PF08833", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08833", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16646", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16646", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-195253", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-195253", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-196299", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-196299", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-201681", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-201681", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-4641257", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4641257", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-4641262", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4641262", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5689880", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5689880", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_990275", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990275", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5P395", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P395", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5P395-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P395-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z054", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z054", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z054-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z054-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5I8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5I8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5I8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5I8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5J4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5J4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5J4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5J4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNIQGKGFPLDLGGSFTEDAPRPPVPGEEGELVSTDPRPVSHGFYSSKSDAVRNETSTATPRRSDLDLGYEPEGSASPTPPYLKWAESLHSLLDDQDGINLFRTFLKQEDCADLLDFWFACSGFRKLEPCVSNEEKRLKLAKAIYKKYILDNNGIVSRQIKPATKSFIKDCVMKLQIDPDMFDQAQTEIQCMIEDNTYPLFLKSDIYLEYTRTGGESPKIYSDPSSGSGTGKGLPGYLPTLNEDEEWKCDQDTEPEASRDSAPSSRLTQKLLLETATQRATSTRRYSEGREFRHGSWREPVNPYYVNTGYAMAPATSANDSEQQSMSSDADTMSLTDSSIDGIPPYRLRKQHRREMQESAKANGRVPLPHIPRTYRMPKDIHVEPEKFAAELINRLEEVQKEREAEEKLEERLKRVRAEEEGEDADISSGPSVISHKMPSAQPFHHFAPRYSEMGCAGMQMRDAHEENPESILDEHVQRVMKTPGCQSPGPGRHSPKPRSPESGHLGKLSGTLGTIPPGHGKHTTKSGMKLDAANLYHHKHVYHHIHHHSMMKPKEQIEAEATQRVQNSFAWNVDSHNYATKSRNYSENLGMAPVPMDSLGYSGKASLLSKRNIKKTDSGKSDGANYEMPGSPEDVERNQKILQWIIEGEKEISRHKKTNHGSSGAKKQLSHDMVRPLSIERPVAVHPWVSAQLRNVVQPSHPFIQDPTMPPNPAPNPLTQLEEARRRLEEEEKRAGKLPLKQRLKPQKRPGSGASQPCENIVVAYYFCGEPIPYRTLVKGRVVTLGQFKELLTKKGNYRYYFKKVSDEFDCGVVFEEVREDDTILPIFEEKIIGKVEKID", "length": 841, "header": "tr|A0A1D5P395-1|A0A1D5P395_CHICK Isoform 1 of Axin-1 OS=Gallus gallus OX=9031 GN=AXIN1 PE=4 SV=1 CANONICAL=A0A1D5P395-1" }, "isoforms": [ { "isoform_ac": "A0A1D5P395-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P395/entry#A0A1D5P395-1", "sequence": { "sequence": "MNIQGKGFPLDLGGSFTEDAPRPPVPGEEGELVSTDPRPVSHGFYSSKSDAVRNETSTATPRRSDLDLGYEPEGSASPTPPYLKWAESLHSLLDDQDGINLFRTFLKQEDCADLLDFWFACSGFRKLEPCVSNEEKRLKLAKAIYKKYILDNNGIVSRQIKPATKSFIKDCVMKLQIDPDMFDQAQTEIQCMIEDNTYPLFLKSDIYLEYTRTGGESPKIYSDPSSGSGTGKGLPGYLPTLNEDEEWKCDQDTEPEASRDSAPSSRLTQKLLLETATQRATSTRRYSEGREFRHGSWREPVNPYYVNTGYAMAPATSANDSEQQSMSSDADTMSLTDSSIDGIPPYRLRKQHRREMQESAKANGRVPLPHIPRTYRMPKDIHVEPEKFAAELINRLEEVQKEREAEEKLEERLKRVRAEEEGEDADISSGPSVISHKMPSAQPFHHFAPRYSEMGCAGMQMRDAHEENPESILDEHVQRVMKTPGCQSPGPGRHSPKPRSPESGHLGKLSGTLGTIPPGHGKHTTKSGMKLDAANLYHHKHVYHHIHHHSMMKPKEQIEAEATQRVQNSFAWNVDSHNYATKSRNYSENLGMAPVPMDSLGYSGKASLLSKRNIKKTDSGKSDGANYEMPGSPEDVERNQKILQWIIEGEKEISRHKKTNHGSSGAKKQLSHDMVRPLSIERPVAVHPWVSAQLRNVVQPSHPFIQDPTMPPNPAPNPLTQLEEARRRLEEEEKRAGKLPLKQRLKPQKRPGSGASQPCENIVVAYYFCGEPIPYRTLVKGRVVTLGQFKELLTKKGNYRYYFKKVSDEFDCGVVFEEVREDDTILPIFEEKIIGKVEKID", "length": 841, "header": "tr|A0A1D5P395-1|A0A1D5P395_CHICK Isoform 1 of Axin-1 OS=Gallus gallus OX=9031 GN=AXIN1 PE=4 SV=1 CANONICAL=A0A1D5P395-1" }, "locus": { "chromosome": "14", "start_pos": 12235598, "end_pos": 12169271, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040823.1", "url": "https://www.ensembl.org/id/ENSGALT00010040823.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023787.1", "url": "https://www.ensembl.org/id/ENSGALP00010023787.1" } ] } }, { "isoform_ac": "A0A8V0Z054-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P395/entry#A0A8V0Z054-1", "sequence": { "sequence": "MNIQGKGFPLDLGGSFTEDAPRPPVPGEEGELVSTDPRPVSHGFYSSKSDAVRNETSTATPRRSDLDLGYEPEGSASPTPPYLKWAESLHSLLDDQDGINLFRTFLKQEDCADLLDFWFACSGFRKLEPCVSNEEKRLKLAKAIYKKYILDNNGIVSRQIKPATKSFIKDCVMKLQIDPDMFDQAQTEIQCMIEDNTYPLFLKSDIYLEYTRTGGESPKIYSDPSSGSGTGKGLPGYLPTLNEDEEWKCDQDTEPEASRDSAPSSRLTQKLLLETATQRATSTRRYSEGREFRHGSWREPVNPYYVNTGYAMAPATSANDSEQQSMSSDADTMSLTDSSIDGIPPYRLRKQHRREMQESAKANGRVPLPHIPIFVFSLLSLLLLAE", "length": 386, "header": "tr|A0A8V0Z054-1|A0A1D5P395_CHICK Computationally mapped isoform of Axin-1 OS=Gallus gallus OX=9031 GN=AXIN1 PE=4 SV=1 CANONICAL=A0A1D5P395-1" }, "locus": { "chromosome": "14", "start_pos": 12219952, "end_pos": 12169271, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040818.1", "url": "https://www.ensembl.org/id/ENSGALT00010040818.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023782.1", "url": "https://www.ensembl.org/id/ENSGALP00010023782.1" } ] } }, { "isoform_ac": "A0A8V0Z5I8-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P395/entry#A0A8V0Z5I8-1", "sequence": { "sequence": "MNIQGKGFPLDLGGSFTEDAPRPPVPGEEGELVSTDPRPVSHGFYSSKSDAVRNETSTATPRRSDLDLGYEPEGSASPTPPYLKWAESLHSLLDDQDGINLFRTFLKQEDCADLLDFWFACSGFRKLEPCVSNEEKRLKLAKAIYKKYILDNNGIVSRQIKPATKSFIKDCVMKLQIDPDMFDQAQTEIQCMIEDNTYPLFLKSDIYLEYTRTGGESPKIYSDPSSGSGTGKGLPGYLPTLNEDEEWKCDQDTEPEASRDSAPSSRLTQKLLLETATQRATSTRRYSEGREFRHGSWREPVNPYYVNTGYAMAPATSANDSEQQSMSSDADTMSLTDSSIDGIPPYRLRKQHRREMQESAKANGRVPLPHIPVSTCIALLAQASV", "length": 385, "header": "tr|A0A8V0Z5I8-1|A0A8V0Z5I8_CHICK Computationally mapped isoform of Axin 1 OS=Gallus gallus OX=9031 GN=AXIN1 PE=4 SV=1 CANONICAL=A0A1D5P395-1" }, "locus": { "chromosome": "14", "start_pos": 12213608, "end_pos": 12169271, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040816.1", "url": "https://www.ensembl.org/id/ENSGALT00010040816.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023780.1", "url": "https://www.ensembl.org/id/ENSGALP00010023780.1" } ] } }, { "isoform_ac": "A0A8V0Z5J4-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P395/entry#A0A8V0Z5J4-1", "sequence": { "sequence": "MNIQGKGFPLDLGGSFTEDAPRPPVPGEEGELVSTDPRPVSHGFYSSKSDAVRNETSTATPRRSDLDLGYEPEGSASPTPPYLKWAESLHSLLDDQDGINLFRTFLKQEDCADLLDFWFACSGFRKLEPCVSNEEKRLKLAKAIYKKYILDNNGIVSRQIKPATKSFIKDCVMKLQIDPDMFDQAQTEIQCMIEDNTYPLFLKSDIYLEYTRTGGESPKIYSDPSSGSGTGKGLPGYLPTLNEDEEWKCDQDTEPEASRDSAPSSRLTQKLLLETATQRATSTRRYSEGREFRHGSWREPVNPYYVNTGYAMAPATSANDSEQQSMSSDADTMSLTDSSIDGIPPYRLRKQHRREMQESAKANGRVPLPHIPRTYRMPKDIHVEPEKFAAELINRLEEVQKEREAEEKLEERLKRVRAEEEGEDADISSGPSVISHKMPSAQPFHHFAPRYSEMGCAGMQMRDAHEENPESILDEHVQRVMKTPGCQSPGPGRHSPKPRSPESGHLGKLSGTLGTIPPGHGKHTTKSGMKLDAANLYHHKHVYHHIHHHSMMKPKEQIEAEATQRVQNSFAWNVDSHNYATKSRNYSENLGMAPVPMDSLGYSSSGAKKQLSHDMVRPLSIERPVAVHPWVSAQLRNVVQPSHPFIQDPTMPPNPAPNPLTQLEEARRRLEEEEKRAGKLPLKQRLKPQKRPGSGASQPCENIVVAYYFCGEPIPYRTLVKGRVVTLGQFKELLTKKGNYRYYFKKVSDEFDCGVVFEEVREDDTILPIFEEKIIGKVEKID", "length": 782, "header": "tr|A0A8V0Z5J4-1|A0A1D5P395_CHICK Computationally mapped isoform of Axin-1 OS=Gallus gallus OX=9031 GN=AXIN1 PE=4 SV=1 CANONICAL=A0A1D5P395-1" }, "locus": { "chromosome": "14", "start_pos": 12235598, "end_pos": 12169271, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040821.1", "url": "https://www.ensembl.org/id/ENSGALT00010040821.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023785.1", "url": "https://www.ensembl.org/id/ENSGALP00010023785.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 79, "start_aa": "Thr", "end_pos": 79, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr79", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "Semaphorin3A-induced axonal transport mediated through phosphorylation of Axin-1 by GSK3\u03b2.", "journal": "Brain research", "date": "2015-02-19", "authors": "Hida Tomonobu, Nakamura Fumio, Usui Hiroshi, Takeuchi Kan, Yamashita Naoya, Goshima Yoshio", "evidence": [ { "database": "RefSeq", "id": "NP_990275", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990275" } ], "reference": [ { "type": "PubMed", "id": "25528666", "url": "https://glygen.org/publication/PubMed/25528666" } ] } ], "pathway": [ { "id": "gga:395786", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395786", "resource": "KEGG Pathway" }, { "id": "R-GGA-195253", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-195253", "resource": "Reactome", "description": "Degradation of beta-catenin by the destruction complex" }, { "id": "R-GGA-196299", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-196299", "resource": "Reactome", "description": "Beta-catenin phosphorylation cascade" }, { "id": "R-GGA-201681", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-201681", "resource": "Reactome", "description": "TCF dependent signaling in response to WNT" }, { "id": "R-GGA-4641257", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4641257", "resource": "Reactome", "description": "Degradation of AXIN" }, { "id": "R-GGA-4641262", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4641262", "resource": "Reactome", "description": "Disassembly of the destruction complex and recruitment of AXIN to the membrane" }, { "id": "R-GGA-5689880", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5689880", "resource": "Reactome", "description": "Ub-specific processing proteases" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A5G2RK10-1", "protein_name": "Axin-1", "gene_name": "AXIN1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MNTQEQGFPLDLGASFTEDAPRPPVPGEEGELVSTDPRPVSHSFCSGKGAGIKGETSTATPRRSDLDLGYEPEGSASPTPPYLKWAESLHSLLDDQDGINLFRTFLRQEHCADLLDFWFACSGFRKLEPCDSNEEKRLKLARAIYRRYILDSGGVVSRQTKPATKSFIKDCIAKQQIDPAMFDQAQTEVQSSMEANTYPAFLKSDIYAECTRAGAESPKACGEPGSAAGTGKGVPGYLPTLNEDEEWTCDRGADEEAAGDPAPPGRLTQTLLLLETAAPRACSSRRYSEGREFRHGSWREPVHSYYVNSGYALAPATSANDSEQQSLSSDADSLSLTDSSVDGIPPYRARKQHRREMQESLQVNGRGPLPHIPRTYRMPKEVRVEPQKFAAELIHRLEAVQRTREAEEKLEERLKRVRMEEEGEGGDVSSAPPGASHKLPAAPAWHHFPARYADVGCVGLRDAHEENPESILDEHVQRVMRTPGCQSPGPGHRSPENSHMPKIGVLGAAVPGHGKHAPKLGVKLDAAGLHLHRHSHHHGHHGAARPKEPAEAEASRRVQSSFAWGPELHGHAAKPRSHLESLGTPLNTGDSLAYSGKAGMTSKRSAKKAESGRSASAEAPGPSEDAEKNQKIMQWIIEGEKEISRHRKAGHGSSGAKKQQAHESSRPLSIERPGAVHPWVSAQLRNSVQPSHLFIQDPTMPPNPAPNPLTQLEEARRRLEEEEKRASKVPSKQRYVQGVIQRGRSCARPACTPVLSMVPAVSDLELSEAETKSQRKAGGGSAQPCDSIVVAYYFCGEPIPYRTLVRGRAVTLGQFKELLTKKGNYRYYFKKVSDEFDCGVVFEEVREDEAVLPVFEEKIIGKVEKVD", "length": 867 }, "evidence": [ { "id": "A0A1D5P395", "url": "https://omabrowser.org/oma/group/A0A1D5P395/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0AAA9S6C8-1", "protein_name": "Axin-1", "gene_name": "AXIN1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNIQEQGFPLDLGASFTEDAPRPPVPGEEGELVSTDPRPVSHSFCSGKGAGIKGETSTATPRRSDLDLGYEPEGSASPTPPYLKWAESLHSLLDDQDGINLFRTFLKQEDCADLLDFWFACSGFRKLEPCDSNEEKRLKLARAIYRKYILDNNGIVSRQTKPATKSFIKDCISKQQIDPAMFDQAQTEVQSTMEENTYPSFLKSDIYLEYTRTGSESPKLCSDQSSGSGTGKGVPGYLPTLNEDEEWKCDREVDEDSGRDPAPPGRLTQKLLLETAAPRASSSRRYSEGRELRCGSWREPVNPYYVNSGYALAPATSANDSEQQSLSSDADSLSLTDSSVDGVPPYRTRRQHRREMQESVQANGRVPLPHIPRTYRMPKEVRVEPQKFAAELIHRLEAVQRTREAEEELEERLKRVRMQEEEGEDSDMPSGPQGASHKLPSAPAWHHFPSRYADVGCTGLRDAHEENPESILDEHVQRVMRTPGCQSPGPGHRSPDSAHVPKIGVLGGAMPGHGKHAPKLGAKLDPTGLHLHRHGHHHGHHGAARPKEPAEAEAARRVPGSFAWGPELHGHAAKPRSHVESTGAPPAGGDGLAYGGKVGTTSKRNSKKAELGKSSSTEAPGPSEDAEKNQKIMQWIIEGEKEISRHRKAGHGSSGAKKQQAHESSRPLSIERPGAVHPWVSAQLRSSVQPSHLFIQDPTMPPNPAPNPLTQLEEARRRLEEEEKRASKAPSKQRYVQEVIQRGRCCVRPACTPVLSAVPAVSDLELSETETKSQRKAGGGSTQPCDSIVVAYYFCGEPIPYRTLVRGRAVTLGQFKELLTKKGNYRFYFKKVSDEFECGVVFEEVREDTAVLPVFEEKIIGKVEKVD", "length": 867 }, "evidence": [ { "id": "A0A1D5P395", "url": "https://omabrowser.org/oma/group/A0A1D5P395/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "O15169-1", "protein_name": "Axin-1", "gene_name": "AXIN1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNIQEQGFPLDLGASFTEDAPRPPVPGEEGELVSTDPRPASYSFCSGKGVGIKGETSTATPRRSDLDLGYEPEGSASPTPPYLKWAESLHSLLDDQDGISLFRTFLKQEGCADLLDFWFACTGFRKLEPCDSNEEKRLKLARAIYRKYILDNNGIVSRQTKPATKSFIKGCIMKQLIDPAMFDQAQTEIQATMEENTYPSFLKSDIYLEYTRTGSESPKVCSDQSSGSGTGKGISGYLPTLNEDEEWKCDQDMDEDDGRDAAPPGRLPQKLLLETAAPRVSSSRRYSEGREFRYGSWREPVNPYYVNAGYALAPATSANDSEQQSLSSDADTLSLTDSSVDGIPPYRIRKQHRREMQESVQVNGRVPLPHIPRTYRVPKEVRVEPQKFAEELIHRLEAVQRTREAEEKLEERLKRVRMEEEGEDGDPSSGPPGPCHKLPPAPAWHHFPPRCVDMGCAGLRDAHEENPESILDEHVQRVLRTPGRQSPGPGHRSPDSGHVAKMPVALGGAASGHGKHVPKSGAKLDAAGLHHHRHVHHHVHHSTARPKEQVEAEATRRAQSSFAWGLEPHSHGARSRGYSESVGAAPNASDGLAHSGKVGVACKRNAKKAESGKSASTEVPGASEDAEKNQKIMQWIIEGEKEISRHRRTGHGSSGTRKPQPHENSRPLSLEHPWAGPQLRTSVQPSHLFIQDPTMPPHPAPNPLTQLEEARRRLEEEEKRASRAPSKQRYVQEVMRRGRACVRPACAPVLHVVPAVSDMELSETETRSQRKVGGGSAQPCDSIVVAYYFCGEPIPYRTLVRGRAVTLGQFKELLTKKGSYRYYFKKVSDEFDCGVVFEEVREDEAVLPVFEEKIIGKVEKVD", "length": 862 }, "evidence": [ { "id": "A0A1D5P395", "url": "https://omabrowser.org/oma/group/A0A1D5P395/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "O35625-1", "protein_name": "Axin-1", "gene_name": "Axin1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNVQEQGFPLDLGASFTEDAPRPPVPGEEGELVSTDSRPVNHSFCSGKGTSIKSETSTATPRRSDLDLGYEPEGSASPTPPYLRWAESLHSLLDDQDGISLFRTFLKQEGCADLLDFWFACSGFRKLEPCDSNEEKRLKLARAIYRKYILDSNGIVSRQTKPATKSFIKDCVMKQQIDPAMFDQAQTEIQSTMEENTYPSFLKSDIYLEYTRTGSESPKVCSDQSSGSGTGKGMSGYLPTLNEDEEWKCDQDADEDDGRDPLPPSRLTQKLLLETAAPRAPSSRRYNEGRELRYGSWREPVNPYYVNSGYALAPATSANDSEQQSLSSDADTLSLTDSSVDGIPPYRIRKQHRREMQESIQVNGRVPLPHIPRTYRMPKEIRVEPQKFAEELIHRLEAVQRTREAEEKLEERLKRVRMEEEGEDGEMPSGPMASHKLPSVPAWHHFPPRYVDMGCSGLRDAHEENPESILDEHVQRVMRTPGCQSPGPGHRSPDSGHVAKTAVLGGTASGHGKHVPKLGLKLDTAGLHHHRHVHHHVHHNSARPKEQMEAEVARRVQSSFSWGPETHGHAKPRSYSENAGTTLSAGDLAFGGKTSAPSKRNTKKAESGKNANAEVPSTTEDAEKNQKIMQWIIEGEKEISRHRKAGHGSSGLRKQQAHESSRPLSIERPGAVHPWVSAQLRNSVQPSHLFIQDPTMPPNPAPNPLTQLEEARRRLEEEEKRANKLPSKQRYVQAVMQRGRTCVRPACAPVLSVVPAVSDLELSETETKSQRKAGGGSAPPCDSIVVAYYFCGEPIPYRTLVRGRAVTLGQFKELLTKKGSYRYYFKKVSDEFDCGVVFEEVREDEAVLPVFEEKIIGKVEKVD", "length": 863 }, "evidence": [ { "id": "A0A1D5P395", "url": "https://omabrowser.org/oma/group/A0A1D5P395/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "O70239-1", "protein_name": "Axin-1", "gene_name": "Axin1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNVQEQGFPLDLGASFTEDAPRPPVPGEEGELVSTDSRPVNHSFCSGKGTSIKSETSTATPRRSDLDLGYEPEGSASPTPPYLRWAESLHSLLDDQDGISLFRTFLKQEGCADLLDFWFACSGFRKLEPCDSNEEKRLKLARAIYRKYILDSNGIVSRQTKPATKSFIKDCVMKQQIDPAMFDQAQTEIQSTMEENTYPSFLKSDIYLEYTRTGSESPKVCSDQSSGSGTGKGMSGYLPTLNEDEEWKCDQDADEDDGRDSVPPSRLTQKLLLETAAPRAPSSRRYNEGRELRYGSWREPVNPYYVNSGYALAPATSANDSEQQSLSSDADTLSLTDSSVDGIPPYRIRKQHRREMQESVQVNGRVPLPHIPRTYRMPKEIRVEPQKFAEELIHRLEAVQRTREAEEKLEERLKRVRMEEEGEDGEMPSGPMASHKLPSVPAWHHFPPRYVDMGCSGLRDAHEENPESILDEHVQRVMRTPGCQSPGPGHRSPDSGHVAKTAVLGGTASGHGKHAPKLGLKLDSAGLHHHRHVHHHVHHNSARPKEQMEAEAARRVQSSFSWGPETHGHAKPRSYSESTGTNPSAGDLAFGGKASAPSKRNTKKAESGKNASAEVPSTTEDAEKNQKIMQWIIEGEKEISRHRKAGHGSSGMRKQQAHESSRPLSIERPGAVHPWVSAQLRNSVQPSHLFIQDPTMPPNPAPNPLTQLEEARRRLEEEEKRANKLPSKQRTKSQRKAGGGSAPPCDSIVVAYYFCGEPIPYRTLVRGRAVTLGQFKELLTKKGSYRYYFKKVSDEFDCGVVFEEVREDEAILPVFEEKIIGKVEKVD", "length": 827 }, "evidence": [ { "id": "A0A1D5P395", "url": "https://omabrowser.org/oma/group/A0A1D5P395/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9V407-1", "protein_name": "Axin", "gene_name": "Axn", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSGHPSGIRKHDDNECSGPRPPVPGEESRVKKMTEGVADTSKNSSPSYLNWARTLNHLLEDRDGVELFKKYVEEEAPAYNDHLNFYFACEGLKQQTDPEKIKQIIGAIYRFLRKSQLSISDDLRAQIKAIKTNPEIPLSPHIFDPMQRHVEVTIRDNIYPTFLCSEMYILYIQQMSAQQERCTSSGATGSGSAGSSGSGGSSLAGACALPPTTASGKQQLPQLVPPGAFINLPVSSVSGPPAGTCSASGSVYGPSTSASSSGSISATDTLPRSSTLPTLHEDSVLSLCDDFEKVQMQEGGGSLGSGSVGAGARAPDYPIRLTRDLLIATQKRRLEIRPPGAHGYVYNPSTTNTSYVPNSRVDSERASVSSGGRTDSDTMSISSCSMDGRPYIQRRHSSTESKAIRQSAMANKETNTFQVIPRTQRLHSNEHRPLKEEELVSLLIPKLEEVKRKRDLEERARERNPGAALLTNERSSASDRAFAEAIREKFALDEDNDQDILDQHVSRVWKDQTPHRSPGTMSPCPPIPSRRRTATHDSGMVSDGAMSLSGHSMKHSKSMPDHSSCSRKLTNKWPSMNTDSGISMFSADTVTKYKDASSRSGSSTASKLEEAKRRLEDEPRRSRRYAQPPMQHLSQQPLASFSSSSSGGSISLPHQPPPLPAKPPETIVVFSFCEEPVPYRIKIPGTQPTLRQFKDYLPRRGHFRFFFKTHCEDPDSPVIQEEIVNDSDILPLFGDKAMGLVKPSD", "length": 745 }, "evidence": [ { "id": "A0A1D5P395", "url": "https://omabrowser.org/oma/group/A0A1D5P395/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 14, "go_terms": [ { "name": "molecular adaptor activity", "id": "GO:0060090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060090", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P395", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P395" } ], "pmid": "" }, { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P395", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P395" } ], "pmid": "" }, { "name": "protein domain specific binding", "id": "GO:0019904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019904", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P395", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P395" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P395", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P395" } ], "pmid": "" }, { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P395", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P395" } ], "pmid": "" }, { "name": "ubiquitin protein ligase binding", "id": "GO:0031625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031625", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P395", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P395" } ], "pmid": "" }, { "name": "beta-catenin binding", "id": "GO:0008013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008013", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P395", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P395" } ], "pmid": "" }, { "name": "signaling adaptor activity", "id": "GO:0035591", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035591", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P395", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P395" } ], "pmid": "" }, { "name": "protein serine/threonine kinase activator activity", "id": "GO:0043539", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043539", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P395", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P395" } ], "pmid": "" }, { "name": "p53 binding", "id": "GO:0002039", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002039", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P395", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P395" } ], "pmid": "" }, { "name": "R-SMAD binding", "id": "GO:0070412", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070412", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P395", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P395" } ], "pmid": "" }, { "name": "ubiquitin-like ligase-substrate adaptor activity", "id": "GO:1990756", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990756", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P395", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P395" } ], "pmid": "" }, { "name": "I-SMAD binding", "id": "GO:0070411", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070411", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P395", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P395" } ], "pmid": "" }, { "name": "protein serine/threonine kinase binding", "id": "GO:0120283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120283", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P395", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P395" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 12, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P395", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P395" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P395", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P395" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P395", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P395" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P395", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P395" } ], "pmid": "" }, { "name": "cell cortex", "id": "GO:0005938", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005938", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P395", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P395" } ], 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"MATDPLSELQDDLNLDDTNQSLSQLKLASIDDKNWLADEDPAFPKSEDSKGSPEAVTHLRWDDPYYDIARHHIVEVAGDDKYGRKVILFSACRMPPSHQLDHVKLLGYLKFTLDQYVESDYTLVYLHHGLTSENKPSLSWLRDAYREFDRKYKKNIKALYIVHPTMFIKTLLILFKPLISFKFGRKIFYVNFLSELEEYVKLEQLGIPSQVLKYDEYLRSLQKPLQVPQKPTPPRPPLPNQQFGVSLQHLREKSPDQSPVPLVVRETIAHLQEHALTTEGIFRRSANTQVVKEVQQKYNMDFQQYEDVHLPAVILKTFLRELPEPLLTFGLYSHIVSFQSVEEVNRVDVVRKTLQNLPEENYHVLRLLTAFLVQVSAHSDRNKMTNTNLAVVFGPNLLWAKDAAITLKAINPINTFTKFLLDHQKELFEDVEA", "length": 433, "header": "tr|A0A8V0ZTR7-1|A0A8V0ZTR7_CHICK Isoform 1 of Rho GTPase activating protein 1 OS=Gallus gallus OX=9031 GN=ARHGAP1 PE=4 SV=1 CANONICAL=A0A8V0ZTR7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZKK5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTR7/entry#A0A8V0ZKK5-1", "sequence": { "sequence": "MATDPLSELQDDLNLDDTNQSLSQLKLASIDDKNWLADEDPAFPKSEDSKGSPEAVTHLRWDDPYYDIARHHIVEVAGDDKYGRKVILFSACRMPPSHQLDHVKLLGYLKFTLDQYVESDYTLVYLHHGLTSENKPSLSWLRDAYREFDRKYKKNIKALYIVHPTMFIKTLLILFKPLISFKFGRKIFYVNFLSELEEYVKLEQLGIPSQVLKYDEYLRSLQKPLQVPQKPTPPRPPLPNQQFGVSLQHLREKSPDQSPVPLVVRETIAHLQEHALTTEGIFRRSANTQVVKEVQQKYNMGVPVDFQQYEDVHLPAVILKTFLRELPEPLLTFGLYSHIVSFQSVEEVNRVDVVRKTLQNLPEENYHVLRLLTAFLVQMEPGASPAGRDNSPLQFSACREQIWRVFRKLLLLMVGKCLQILEGTQCKYPLWFAAPHAGAAGSPGAGTVTRAAFASSAFCSPERLLLRYPSCDLSKELGLPAASASGWPRASASAEVWGSHSLYI", "length": 504, "header": "tr|A0A8V0ZKK5-1|A0A8V0ZKK5_CHICK Computationally mapped isoform of Rho GTPase activating protein 1 OS=Gallus gallus OX=9031 GN=ARHGAP1 PE=4 SV=1 CANONICAL=A0A8V0ZTR7-1" }, "locus": { "chromosome": "5", "start_pos": 23011272, "end_pos": 22990388, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056022.1", "url": "https://www.ensembl.org/id/ENSGALT00010056022.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033898.1", "url": "https://www.ensembl.org/id/ENSGALP00010033898.1" } ] } }, { "isoform_ac": "A0A8V0ZQW5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTR7/entry#A0A8V0ZQW5-1", "sequence": { "sequence": "MATDPLSELQDDLNLDDTNQSLSQLKLASIDDKNWLADEDPAFPKSEDSKGSPEAVTHLRWDDPYYDIARHHIVEVAGDDKYGRKVILFSACRMPPSHQLDHVKLLGYLKFTLDQYVESDYTLVYLHHGLTSENKPSLSWLRDAYREFDRKYKKNIKALYIVHPTMFIKTLLILFKPLISFKFGRKIFYVNFLSELEEYVKLEQLGIPSQVLKYDEYLRSLQKPLQVPQKPTPPRPPLPNQQFGVSLQHLREKSPDQSPVPLVVRETIAHLQRLLQVSQLNNSQQGAQVAKKANGILARIRKSVVSRSREVIVTLYSALVRPHLEYCVQFWAPHCKKDIEAVERVQRRAMKLVGGMEHRPYEEHVRQLGLFRLPAQAPREKRRLRGDFITLYSYLKGGCGELGVGHLL", "length": 408, "header": "tr|A0A8V0ZQW5-1|A0A8V0ZQW5_CHICK Computationally mapped isoform of Rho GTPase activating protein 1 OS=Gallus gallus OX=9031 GN=ARHGAP1 PE=4 SV=1 CANONICAL=A0A8V0ZTR7-1" }, "locus": { "chromosome": "5", "start_pos": 23010534, "end_pos": 22990388, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056017.1", "url": "https://www.ensembl.org/id/ENSGALT00010056017.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033895.1", "url": "https://www.ensembl.org/id/ENSGALP00010033895.1" } ] } }, { "isoform_ac": "A0A8V0ZTR7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTR7/entry#A0A8V0ZTR7-1", "sequence": { "sequence": "MATDPLSELQDDLNLDDTNQSLSQLKLASIDDKNWLADEDPAFPKSEDSKGSPEAVTHLRWDDPYYDIARHHIVEVAGDDKYGRKVILFSACRMPPSHQLDHVKLLGYLKFTLDQYVESDYTLVYLHHGLTSENKPSLSWLRDAYREFDRKYKKNIKALYIVHPTMFIKTLLILFKPLISFKFGRKIFYVNFLSELEEYVKLEQLGIPSQVLKYDEYLRSLQKPLQVPQKPTPPRPPLPNQQFGVSLQHLREKSPDQSPVPLVVRETIAHLQEHALTTEGIFRRSANTQVVKEVQQKYNMDFQQYEDVHLPAVILKTFLRELPEPLLTFGLYSHIVSFQSVEEVNRVDVVRKTLQNLPEENYHVLRLLTAFLVQVSAHSDRNKMTNTNLAVVFGPNLLWAKDAAITLKAINPINTFTKFLLDHQKELFEDVEA", "length": 433, "header": "tr|A0A8V0ZTR7-1|A0A8V0ZTR7_CHICK Isoform 1 of Rho GTPase activating protein 1 OS=Gallus gallus OX=9031 GN=ARHGAP1 PE=4 SV=1 CANONICAL=A0A8V0ZTR7-1" }, "locus": { "chromosome": "5", "start_pos": 23007567, "end_pos": 22990388, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055998.1", "url": "https://www.ensembl.org/id/ENSGALT00010055998.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033886.1", "url": "https://www.ensembl.org/id/ENSGALP00010033886.1" } ] } }, { "isoform_ac": "A0A8V0ZTS4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTR7/entry#A0A8V0ZTS4-1", "sequence": { "sequence": "MATDPLSELQDDLNLDDTNQSLSQLKLASIDDKNWLADEDPAFPKSEDSKGSPEAVTHLRWDDPYYDIARHHIVEVADQGALDGAQPGDDKYGRKVILFSACRMPPSHQLDHVKLLGYLKFTLDQYVESDYTLVYLHHGLTSENKPSLSWLRDAYREFDRKYKKNIKALYIVHPTMFIKTLLILFKPLISFKFGRKIFYVNFLSELEEYVKLEQLGIPSQVLKYDEYLRSLQKPLQVPQKPTPPRPPLPNQQFGVSLQHLREKSPDQSPVPLVVRETIAHLQEHALTTEGIFRRSANTQVVKEVQQKYNMGVPVDFQQYEDVHLPAVILKTFLRELPEPLLTFGLYSHIVSFQSVEEVNRVDVVRKTLQNLPEENYHVLRLLTAFLVQVSAHSDRNKMTNTNLAVVFGPNLLWAKDAAITLKAINPINTFTKFLLDHQKELFEDVEA", "length": 447, "header": "tr|A0A8V0ZTS4-1|A0A8V0ZTS4_CHICK Computationally mapped isoform of Rho GTPase activating protein 1 OS=Gallus gallus OX=9031 GN=ARHGAP1 PE=4 SV=1 CANONICAL=A0A8V0ZTR7-1" }, "locus": { "chromosome": "5", "start_pos": 23007567, "end_pos": 22990388, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056007.1", "url": "https://www.ensembl.org/id/ENSGALT00010056007.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033891.1", "url": "https://www.ensembl.org/id/ENSGALP00010033891.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:428865", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428865", "resource": "KEGG Pathway" }, { "id": "R-GGA-8980692", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8980692", "resource": "Reactome", "description": "RHOA GTPase cycle" }, { "id": "R-GGA-9013026", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013026", "resource": "Reactome", "description": "RHOB GTPase cycle" }, { "id": "R-GGA-9013106", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013106", "resource": "Reactome", "description": "RHOC GTPase cycle" }, { "id": "R-GGA-9013148", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013148", "resource": "Reactome", "description": "CDC42 GTPase cycle" }, { "id": "R-GGA-9013149", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013149", "resource": "Reactome", "description": "RAC1 GTPase cycle" }, { "id": "R-GGA-9013404", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013404", "resource": "Reactome", "description": "RAC2 GTPase cycle" }, { "id": "R-GGA-9013406", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013406", "resource": "Reactome", "description": "RHOQ GTPase cycle" }, { "id": "R-GGA-9013408", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013408", "resource": "Reactome", "description": "RHOG GTPase cycle" }, { "id": "R-GGA-9013409", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013409", "resource": "Reactome", "description": "RHOJ GTPase cycle" }, { "id": "R-GGA-9013423", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013423", "resource": "Reactome", "description": "RAC3 GTPase cycle" }, { "id": "R-GGA-9035034", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9035034", "resource": "Reactome", "description": "RHOF GTPase cycle" }, { "id": "R-GGA-9696270", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9696270", "resource": "Reactome", "description": "RND2 GTPase cycle" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2JYR5-1", "protein_name": "Rho GTPase activating protein 1", "gene_name": "Arhgap1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSLKDRTGSLEVIAGSGRSTRKAMFGPGSKPEVGRRYGGSGWELRAPEGAVPIPTSEPDVCRALTGVAKGALPERGELQSAGSHWAWWLLFWFSLAMDPLSELQDDLTLDDTSQALNQLKLASIDEKNWPSDEMPDFPKSDDSKSSSPEPVTHLKWDDPYYDIARHQIVEVAGDDKYGRKIIVFSACRMPPSHQLDHSKLLGYLKHTLDQYVESDYTLLYLHHGLTSDNKPSLSWLRDAYREFDRKYKKNIKALYIVHPTMFIKTLLILFKPLISFKFGRKIFYVNYLSELSEHVKLEQLGIPRQVLKYDDFLKSTQKSPATAPKPMPPRPPLPNQQFGVSLQHLREKNPNQEPIPIVLRETVAYLQAHALTAEGIFRRSANTQVVREVQQKYNMGLPVDFDQYNELHLPAVILKTFLRELPEPLLTFDLYPHIVGFLDLDDDQRVEVTQQVLQTLPEENYRVLHFLTAFLVQVSAHSYQNRMNNTNLAVVFGPNLLWAKDAAITLKAINPINTFTKFLLDHQGELFPSTDAQGV", "length": 535 }, "evidence": [ { "id": "A0A8V0ZTR7", "url": "https://omabrowser.org/oma/group/A0A8V0ZTR7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A5G2QDJ1-1", "protein_name": "Rho GTPase activating protein 1", "gene_name": "ARHGAP1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDPLSELQDDLTVDDTSQALNQLKLASIDEKNWPSDEMPDFPKSDDSKSSSPEPVTHLKWDDPYYDIARHQIVEVAGDDKYGRKIIVFSACRMPPSHQLDHSKLLGYLKHTLDQYVESDYTLLYLHHGLTSDNKPSLSWLRDAYREFDRKYKKNIKALYIVHPTMFIKTLLILFKPIISFKFGQKIFYVNYLSELSEHVKLEQLGIPRQVLKYDDFLKSTQKSPATAPKPMPPRPPLPNQQFGVSLQHLREKNPDQEPIPLVLRETVAYLQAHALTTEGIFRRSANTQVVREVQQKYNMGLPVDFDQYNELHLPAVILKTFLRELPEPLLTFDLYSHVVGFLSIDESQRVQATLQVFQTLPEENYLVLRFLTAFLVQISALCDQNKMTNTNLAVVFGPNLLWAKDAAITLKAINPINTFTKFLLDHQGELFPSPDAKGL", "length": 439 }, "evidence": [ { "id": "A0A8V0ZTR7", "url": "https://omabrowser.org/oma/group/A0A8V0ZTR7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F6RWK1-1", "protein_name": "Rho GTPase activating protein 1", "gene_name": "ARHGAP1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MDPLSELQDDLTLDDPSQALNQLKLASIDEKNWPSDEMPDFPKSDDSKSSSPEPVTHLKWDDPYYDIARHQIVEVAGDDKYGRKIIVFSACRMPPSHQLDHSKLLGYLKHTLDQYVESDYTLLYLHHGLTSDNKPSFSWLRDAYREFDRKYKKNIKALYIVHPTMFIKTLLILFKPIISFKFGQKIFYVNYLSELSEHVKLEQLGIPRQVLKYDDFLKSTQKSPATAPKPMPPRPPLPNQQFGVSLQQLREKNPEQQPIPLVLRETVAYLRAHALTTEGIFRRSANTQVVREVQHKYNMGLSVDFEQYNELHLPAVILKTFLRELPEPLLTFDLYSHVVGFLNIDESQRVKATLQALQTLPEENYLVLRFLTAFLVQISALSDQNKMTNTNLAVVFGPNLLWAKDAAITLKAINPINTFTKFLLDHQGELFPSPDAKGL", "length": 439 }, "evidence": [ { "id": "A0A8V0ZTR7", "url": "https://omabrowser.org/oma/group/A0A8V0ZTR7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3GYJ1-1", "protein_name": "Rho GTPase-activating protein 1", "gene_name": "Arhgap1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDPLSELQDDLTLDDTSQALNQLKLASIDEKNWPSDEMPDFPKSDDSKSSSPEPVTHLKWDDPYYDIARHQIVEVAGDDKYGRKIIVFSACRMPPSHQLDHSKLLGYLKHTLDQYVESDYTLLYLHHGLTSDNKPSLSWLRDAYREFDRKYKKNIKALYIVHPTMFIKTLLILFKPLISFKFGRKIFYVNYLSELSEHVKLEQLGIPRQVLKYDDFLKSTQKSPATAPKPMPPRPPLPNQQFGVSLQHLQEKNPDQVPIPIVLRETVAYLQAHALTTEGIFRRSANTQVVREVQQKYNMGLPVDFDQYNELHLPAVILKTFLRELPEPLLTFDLYPHVVGFLNIDESQRVEVTQQALQTLPEENYQVLRFLTAFLVQVSAHCDQNKMTNTNLAVVFGPNLLWAKDAAITLKAINPINTFTKFLLDHQGELFPSTDAQGV", "length": 439 }, "evidence": [ { "id": "A0A8V0ZTR7", "url": "https://omabrowser.org/oma/group/A0A8V0ZTR7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q07960-1", "protein_name": "Rho GTPase-activating protein 1", "gene_name": "ARHGAP1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDPLSELQDDLTLDDTSEALNQLKLASIDEKNWPSDEMPDFPKSDDSKSSSPELVTHLKWDDPYYDIARHQIVEVAGDDKYGRKIIVFSACRMPPSHQLDHSKLLGYLKHTLDQYVESDYTLLYLHHGLTSDNKPSLSWLRDAYREFDRKYKKNIKALYIVHPTMFIKTLLILFKPLISFKFGQKIFYVNYLSELSEHVKLEQLGIPRQVLKYDDFLKSTQKSPATAPKPMPPRPPLPNQQFGVSLQHLQEKNPEQEPIPIVLRETVAYLQAHALTTEGIFRRSANTQVVREVQQKYNMGLPVDFDQYNELHLPAVILKTFLRELPEPLLTFDLYPHVVGFLNIDESQRVPATLQVLQTLPEENYQVLRFLTAFLVQISAHSDQNKMTNTNLAVVFGPNLLWAKDAAITLKAINPINTFTKFLLDHQGELFPSPDPSGL", "length": 439 }, "evidence": [ { "id": "A0A8V0ZTR7", "url": "https://omabrowser.org/oma/group/A0A8V0ZTR7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5FWK3-1", "protein_name": "Rho GTPase-activating protein 1", "gene_name": "Arhgap1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDPLSELQDDLTLDDTSQALNQLKLASIDEKNWPSDEMPDFPKSDDSKSSSPEPVTHLKWDDPYYDIARHQIVEVAGDDKYGRKIIVFSACRMPPSHQLDHSKLLGYLKHTLDQYVESDYTLLYLHHGLTSDNKPSLSWLRDAYREFDRKYKKNIKALYIVHPTMFIKTLLILFKPLISFKFGRKIFYVNYLSELSEHVKLEQLGIPRQVLKYDDFLKSTQKSPATAPKPMPPRPPLPNQQFGVSLQHLQEKSPGQDPIPIVLRETVAYLQAHALTTEGIFRRSANTQVVREVQQKYNMGLPVDFDQYNELHLPAVILKTFLRELPEPLLTFDLYPHVVGFLNIDESQRVEVTQQVLQTLPEENYQVLHFLTAFLVQISAHCDQNKMTNTNLAVVFGPNLLWAKDAAITLKAINPINTFTKFLLDHQGELFPSTDAQGV", "length": 439 }, "evidence": [ { "id": "A0A8V0ZTR7", "url": "https://omabrowser.org/oma/group/A0A8V0ZTR7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VTU3-1", "protein_name": "Rho GTPase-activating protein 68F", "gene_name": "RhoGAP68F", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDAHSRFAPRLPGPAINPIVDNSDEPQPSLSDLHDFEPKLEFDDTELLAPSPLEKDVMVGDFVLAEDPELEPEEDVNPLEDDFEDQLREQSENFQTPRNKCDFLGTDKQGRHIFGIYASRFPEKSQLEGFVREIIKEIEPFVENDYILVYFHQGLKEDNKPSAQFLWNSYKELDRNFRKNLKTLYVVHPTWFIRVIWNFFSPFISDKFRKKLVYISSLDELRQALGLNKLKLPDNICDLDDKLNPSRKPSTPPPSSNINASRQQQHKMATTHQFGVPLKFIVMNSPCLNSIPPIVRKCVDSLSITGVIDTEGIFRRSGNHSEIMALKERVNRGEDVDLKSVNVHVIAGLLKSFLRDLAEPLLTFELYEDVTGFLDWPKEERSRNVTQLIREKLPEENYELFKYIVEFLVRVMDCEDLNKMTSSNLAIVFGPNFLWSRSTSTSLEEIAPINAFVDFVLQNHKDIYLIDVNQRTVSVD", "length": 476 }, "evidence": [ { "id": "A0A8V0ZTR7", "url": "https://omabrowser.org/oma/group/A0A8V0ZTR7/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTR7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTR7" } ], "pmid": "" }, { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTR7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTR7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 9, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTR7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTR7" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTR7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTR7" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTR7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTR7" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTR7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTR7" } ], "pmid": "" }, { "name": "endosome membrane", "id": "GO:0010008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010008", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTR7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTR7" } ], "pmid": "" }, { "name": "ruffle", "id": "GO:0001726", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001726", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTR7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTR7" } ], "pmid": "" }, { "name": "sorting endosome", "id": "GO:0097443", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097443", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTR7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTR7" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTR7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTR7" } ], "pmid": "" }, { "name": "plasma membrane bounded cell projection", "id": "GO:0120025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120025", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTR7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTR7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "small GTPase-mediated signal transduction", "id": "GO:0007264", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007264", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTR7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTR7" } ], "pmid": "" }, { "name": "endosomal transport", "id": "GO:0016197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016197", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTR7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTR7" } ], "pmid": "" }, { "name": "transferrin transport", "id": "GO:0033572", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033572", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTR7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTR7" } ], "pmid": "" }, { "name": "negative regulation of endocytic recycling", "id": "GO:2001136", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2001136", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTR7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTR7" } ], "pmid": "" }, { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTR7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTR7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 19, "end_pos": 21, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZTR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTR7" }, { "id": "PS50191", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50191" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CRAL-TRIO", "eco_id": "ECO_0000259", "start_pos": 64, "end_pos": 219, "start_aa": "Pro", "end_aa": "Arg", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZTR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTR7" }, { "id": "PS50238", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50238" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Rho-GAP", "eco_id": "ECO_0000259", "start_pos": 245, "end_pos": 428, "start_aa": "Val", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 19, "end_pos": 21 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZSJ4-1", "uniprot_ac": "A0A8V0ZSJ4", "uniprot_id": "A0A8V0ZSJ4_CHICK", "mass": { "chemical_mass": 96284.0, "monoisotopic_mass": 96284.0 }, "refseq": { "ac": "XP_421626", "name": "lymphoid-specific helicase isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_421626" }, "gene_names": [ { "name": "HELLS", "type": "recommended", "evidence": [ { "id": "A0A8V0ZSJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSJ4" } ] }, { "name": "HELLS", "type": "synonym", "evidence": [ { "id": "XP_421626", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_421626" } ] } ], "protein_names": [ { "name": "Proliferation-associated SNF2-like protein", "type": "recommended", "evidence": [ { "id": "A0A8V0ZSJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSJ4/entry#names_and_taxonomy" } ] }, { "name": "lymphoid-specific helicase isoform X1", "type": "synonym", "evidence": [ { "id": "XP_421626", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_421626" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052537.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 19, 2013 this sequence version replaced XP_421626.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_421626", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_421626" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSJ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSJ4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "HELLS", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSJ4", "locus": { "chromosome": "6", "start_pos": 17253028, "end_pos": 17274163, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021750", "url": "https://www.ensembl.org/id/ENSGALG00010021750" } ] } } ], "crossref": [ { "id": "A0A8V0ZSJ4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZSJ4", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd18009", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18009", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18793", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18793", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "423750", "url": "https://www.ncbi.nlm.nih.gov/gene/423750", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000330", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000330", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001650", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001650", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014001", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014001", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038718", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038718", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044753", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044753", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049730", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049730", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "WNICRID", "url": "https://omabrowser.org/oma/group/WNICRID/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZLT5", "url": "https://www.orthodb.org/?gene=A0A8V0ZLT5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZSJ4", "url": "https://www.orthodb.org/?gene=A0A8V0ZSJ4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47161", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47161", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47161:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47161:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00176", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00176", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00271", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00271", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_421626", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_421626", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "13065", "url": "https://www.rhea-db.org/rhea/13065", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZLT5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLT5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLT5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLT5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZSJ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSJ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZSJ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSJ4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPAQNVASGGEPPGAEMGEQEVVITPAMLAEEEQLEAAGLEKERQMMEKARSAWDRESSEMRYKRLQHLLEKSNIYSKFLLTKMEQQQLEEQKRKEKLEKKREMMLKSAKGQNPADGKEEKSATKKKRGRDDGTYNISEIMSKEEILSVAKKSKVENQDESSAGNLCPEDLQKNGDSNSVIKDRLCQAVRHSAKQFLDPVRKFNGQPVPFQQPKIFTGGVMRWYQVEGMEWLRMLWENGINGILADEMGLGKTIQCIATIALMVERGVPGPFLVCGPLSTLPNWMSEFKRFTPEIPLMLYHGAQQERRKLVRKIHGRQGSLKIHPVVITSFEIAMRDRNALQSCFWKYLIVDEGHRIKNMNCRLIRELKRFNADNKLLLTGTPLQNNLAELWSLLNFLLPDVFDDLKSFESWFDITSITETAEDIIAKEKEQNILHMLHQILTPFLLRRLKSDVALEVPPKREVVVYAPLAKKQETFYTAIVNRTIRNLLGNNEEEVVELSPTGRPKRRSRKLVDYCEEHNGSPDDLEKLINRTQEEVVKERPVVEVSMPMDSEVNLKLQNIMMLLRKCCNHPYLIEYPLDPATQQFKVDEDLVKNSGKFLLLDRMLPELKKRGHKVLMFSQMTMMLDILMDYCYLRGFKFSRLDGSMSYSDREENMHQFNNDPEVFLFLVSTRAGGLGINLTAADTVIIYDSDWNPQSDLQAQDRCHRIGQTKPVVVYRLVTANTIDQKIVERAAAKRKLEKLIIHKNQFKGGKSGLAQSKSCLDPQELIELLKSRDYEREVKGSKEKVISDKDLELLLDRSDLIDQMKTSETVKKEKMGVFKVLEESSGSNAECVF", "length": 838, "header": "tr|A0A8V0ZSJ4-1|A0A8V0ZSJ4_CHICK Isoform 1 of Proliferation-associated SNF2-like protein OS=Gallus gallus OX=9031 GN=HELLS PE=3 SV=1 CANONICAL=A0A8V0ZSJ4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZLT5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSJ4/entry#A0A8V0ZLT5-1", "sequence": { "sequence": "MHNPGCQGRTSWDSGKREREAHGPQEPPGAEMGEQEVVITPAMLAEEEQLEAAGLEKERQMMEKARSAWDRESSEMRYKRLQHLLEKSNIYSKFLLTKMEQQQLEEQKRKEKLEKKREMMLKSAKGQNPADGKEEKSATKKKRGRDDGTYNISEIMSKEEILSVAKKSKVENQDESSAGNLCPEDLQKNGDSNSVIKDRLCQAVRHSAKQFLDPVRKFNGQPVPFQQPKIFTGGVMRWYQVEGMEWLRMLWENGINGILADEMGLGKTIQCIATIALMVERGVPGPFLVCGPLSTLPNWMSEFKRFTPEIPLMLYHGAQQERRKLVRKIHGRQGSLKIHPVVITSFEIAMRDRNALQSCFWKYLIVDEGHRIKNMNCRLIRELKRFNADNKLLLTGTPLQNNLAELWSLLNFLLPDVFDDLKSFESWFDITSITETAEDIIAKEKEQNILHMLHQILTPFLLRRLKSDVALEVPPKREVVVYAPLAKKQETFYTAIVNRTIRNLLGNNEEEVVELSPTGRPKRRSRKLVDYCEEHNGSPDDLEKLINRTQEEVVKERPVVEVSMPMDSEVNLKLQNIMMLLRKCCNHPYLIEYPLDPATQQFKVDEDLVKNSGKFLLLDRMLPELKKRGHKVLMFSQMTMMLDILMDYCYLRGFKFSRLDGSMSYSDREENMHQFNNDPEVFLFLVSTRAGGLGINLTAADTVIIYDSDWNPQSDLQAQDRCHRIGQTKPVVVYRLVTANTIDQKIVERAAAKRKLEKLIIHKNQFKGGKSGLAQSKSCLDPQELIELLKSRDYEREVKGSKEKVISDKDLELLLDRSDLIDQMKTSETVKKEKMGVFKVLEESSGSNAECVF", "length": 853, "header": "tr|A0A8V0ZLT5-1|A0A8V0ZLT5_CHICK Computationally mapped isoform of Proliferation-associated SNF2-like protein OS=Gallus gallus OX=9031 GN=HELLS PE=3 SV=1 CANONICAL=A0A8V0ZSJ4-1" }, "locus": { "chromosome": "6", "start_pos": 17274107, "end_pos": 17253795, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052865.1", "url": "https://www.ensembl.org/id/ENSGALT00010052865.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031771.1", "url": "https://www.ensembl.org/id/ENSGALP00010031771.1" } ] } }, { "isoform_ac": "A0A8V0ZSJ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSJ4/entry#A0A8V0ZSJ4-1", "sequence": { "sequence": "MPAQNVASGGEPPGAEMGEQEVVITPAMLAEEEQLEAAGLEKERQMMEKARSAWDRESSEMRYKRLQHLLEKSNIYSKFLLTKMEQQQLEEQKRKEKLEKKREMMLKSAKGQNPADGKEEKSATKKKRGRDDGTYNISEIMSKEEILSVAKKSKVENQDESSAGNLCPEDLQKNGDSNSVIKDRLCQAVRHSAKQFLDPVRKFNGQPVPFQQPKIFTGGVMRWYQVEGMEWLRMLWENGINGILADEMGLGKTIQCIATIALMVERGVPGPFLVCGPLSTLPNWMSEFKRFTPEIPLMLYHGAQQERRKLVRKIHGRQGSLKIHPVVITSFEIAMRDRNALQSCFWKYLIVDEGHRIKNMNCRLIRELKRFNADNKLLLTGTPLQNNLAELWSLLNFLLPDVFDDLKSFESWFDITSITETAEDIIAKEKEQNILHMLHQILTPFLLRRLKSDVALEVPPKREVVVYAPLAKKQETFYTAIVNRTIRNLLGNNEEEVVELSPTGRPKRRSRKLVDYCEEHNGSPDDLEKLINRTQEEVVKERPVVEVSMPMDSEVNLKLQNIMMLLRKCCNHPYLIEYPLDPATQQFKVDEDLVKNSGKFLLLDRMLPELKKRGHKVLMFSQMTMMLDILMDYCYLRGFKFSRLDGSMSYSDREENMHQFNNDPEVFLFLVSTRAGGLGINLTAADTVIIYDSDWNPQSDLQAQDRCHRIGQTKPVVVYRLVTANTIDQKIVERAAAKRKLEKLIIHKNQFKGGKSGLAQSKSCLDPQELIELLKSRDYEREVKGSKEKVISDKDLELLLDRSDLIDQMKTSETVKKEKMGVFKVLEESSGSNAECVF", "length": 838, "header": "tr|A0A8V0ZSJ4-1|A0A8V0ZSJ4_CHICK Isoform 1 of Proliferation-associated SNF2-like protein OS=Gallus gallus OX=9031 GN=HELLS PE=3 SV=1 CANONICAL=A0A8V0ZSJ4-1" }, "locus": { "chromosome": "6", "start_pos": 17273769, "end_pos": 17253795, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052867.1", "url": "https://www.ensembl.org/id/ENSGALT00010052867.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031773.1", "url": "https://www.ensembl.org/id/ENSGALP00010031773.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2K7M6-1", "protein_name": "Proliferation-associated SNF2-like protein", "gene_name": "Hells", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPAERPASSSGPLAPEMAEQTEPAVITPAMLEEEEQLEAEGLEKERKMLEEARKSWDRESTEIRYRRLQHLLEKSNIYSKFLLTKMEQQQLEEQKKKEKLEKKKRSLKVTEGKNLIDGNEENTVMKKKRGREDESYNISEVMSKEEILSVAKKHKDNEDENSSTTNLCVEDLQKNKDSNSMIKDRLSQTVRQNSKFFFDPVRKCNGQPVPFQQPKHFTGGVMRWYQVEGMEWLRMLWENGINGILADEMGLGKTVQCIATIALMIQRGVPGPFLVCGPLSTLPNWMAEFKRFTPEIPTLLYHGNRQERRKLVKNIHKRQGTLQIHPVVITSFEIAMRDQNALQHCYWKYLIVDEGHRIKNMKCRLIRELKRFNADNKLLLTGTPLQNNLSELWSLLNFLLPDVFDDLKSFESWFDITSLSETAEDIIAKEREQNVLHMLHQILTPFLLRRLKSDVALEVPPKREVVVYAPLCNKQEIFYTAIVNRTIANMFGSCEKETVELSPTGRPKRRSRKSINYSELDQFPSELEKLISQIQPEVKRERTVVEGNIPIESEVNLKLQNIMMLLRKCCNHPYMIEYPIDPVTQEFKIDEELVTNSGKFLILDRMLPELKKRCHKVLVFSQMTSMLDILMDYCHLRNFTFSRLDGSMSYSEREKNIYSFNTDPEVFLFLVSTRAGGLGINLTAADTVIIYDSDWNPQSDLQAQDRCHRIGQTKPVVVYRLVTANTIDQKIVERAAAKRKLEKLIIHKNHFKGGQSGLSQSKNFLDAKELMELLKSRDYEREVKGSREKVISDEDLELLLDRSDLIDQMKASRPIKEKTGIFKILENSEDSSAECLF", "length": 837 }, "evidence": [ { "id": "A0A8V0ZSJ4", "url": "https://omabrowser.org/oma/group/A0A8V0ZSJ4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P43610-1", "protein_name": "Uncharacterized ATP-dependent helicase IRC5", "gene_name": "IRC5", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSRCSNAALMTVVEDAVGARVAARTRNMSNGVNYREKEVNDLTADISDSDSDLDSEDNKHGKGDNDTAPIWLQDDVHSDEDIQLDSEDDSDTEAVQAQVVDKLAKDTKSEQKSLDDELSEMDTKTVSLKLKKLNEFVRQSQVYSSIIADTLLHRSNEVANANTKDNSNSDDEEHSSKKRKTKKKSITDFFKKQKKNEDTTTQNGAPDDAAIKQPRLLKNCILKPYQLEGLNWLITLYENGLNGILADEMGLGKTVQSIALLAFIYEMDTKGPFLVTAPLSTLDNWMNEFAKFAPDLPVLKYYGTNGYKERSAKLKNFFKQHGGTGIVITSYEIILRDTDLIMSQNWKFLIVDEGHRLKNINCRLIKELKKINTSNRLLLTGTPLQNNLAELWSLLNFIMPDIFADFEIFNKWFDFDSLNLGSGSNSEALNKLINDELQKNLISNLHTILKPFLLRRLKKVVLANILPPKREYIINCPMTSAQEKFYKAGLNGKLKKTMFKELIKDFFTLNDEYIGHVSNRSIRDFINYKLSGNETSNTDNKINPTLLQMDKLYKKNLQMEISNKKLQNMMMQLRQIIDSTFLFYFPYLHPEDLTLETLLKTSGKLQILQKLIPPLISEGHKVLIYSQFVNMLDLIEDWCDLNSFATFRIDGSVNNETRKDQLEKFNSSKDKHNIFLLSTRAAGLGINLVGADTVVLFDSDWNPQVDLQAMDRCHRIGQESPVIVYRLCCDNTIEHVILTRAANKRNLERMVIQMGKFNNLKKLALNEGSFLKANKAGVNVTNKDLVQELSMLLMSDESNIGFENGGQKENKATEGQLTDKEVEELTNRSLEAYKANRVVDLPHVKLFETTSGL", "length": 853 }, "evidence": [ { "id": "A0A8V0ZSJ4", "url": "https://omabrowser.org/oma/group/A0A8V0ZSJ4/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q60848-1", "protein_name": "Lymphocyte-specific helicase", "gene_name": "Hells", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAEQTEPAVITPAMLEEEEQLEAAGLEKERKMLEEAQKSWDRESTEIRYRRLQHLLEKSNIYSKFLLTKMEQQQLEEQKKKEKLEKKKRSLKLTEGKSLVDGNGEKPVMKKKRGREDESYNISEVMSKEEILSVAKKHKDNEDESSSTTSLCVEDIQKNKDSNSMIKDRLSQTVRQNSKFFFDPVRKCNGQPVPFQQPKHFTGGVMRWYQVEGMEWLRMLWENGINGILADEMGLGKTVQCIATIALMIQRGVPGPFLVCGPLSTLPNWMAEFKRFTPEIPTLLYHGTREDRRKLVKNIHKRQGTLQIHPVVVTSFEIAMRDQNALQHCYWKYLIVDEGHRIKNMKCRLIRELKRFNADNKLLLTGTPLQNNLSELWSLLNFLLPDVFDDLKSFESWFDITSLSETAEDIIAKEREQNVLHMLHQILTPFLLRRLKSDVALEVPPKREVVVYAPLCNKQEIFYTAIVNRTIANMFGSCEKETVELSPTGRPKRRSRKSINYSELDQFPSELEKLISQIQPEVNRERTVVEGNIPIESEVNLKLRNIMMLLRKCCNHPYMIEYPIDPVTQEFKIDEELVTNSGKFLILDRMLPELKKRGHKVLVFSQMTSMLDILMDYCHLRNFIFSRLDGSMSYSEREKNIYSFNTDPDVFLFLVSTRAGGLGINLTAADTVIIYDSDWNPQSDLQAQDRCHRIGQTKPVVVYRLVTANTIDQKIVERAAAKRKLEKLIIHKNHFKGGQSGLSQSKNFLDAKELMELLKSRDYEREVKGSREKVISDEDLELLLDRSDLIDQMKASRPIKGKTGIFKILENSEDSSAECLF", "length": 821 }, "evidence": [ { "id": "A0A8V0ZSJ4", "url": "https://omabrowser.org/oma/group/A0A8V0ZSJ4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NRZ9-1", "protein_name": "Lymphoid-specific helicase", "gene_name": "HELLS", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPAERPAGSGGSEAPAMVEQLDTAVITPAMLEEEEQLEAAGLERERKMLEKARMSWDRESTEIRYRRLQHLLEKSNIYSKFLLTKMEQQQLEEQKKKEKLERKKESLKVKKGKNSIDASEEKPVMRKKRGREDESYNISEVMSKEEILSVAKKNKKENEDENSSSTNLCVEDLQKNKDSNSIIKDRLSETVRQNTKFFFDPVRKCNGQPVPFQQPKHFTGGVMRWYQVEGMEWLRMLWENGINGILADEMGLGKTVQCIATIALMIQRGVPGPFLVCGPLSTLPNWMAEFKRFTPDIPTMLYHGTQEERQKLVRNIYKRKGTLQIHPVVITSFEIAMRDRNALQHCYWKYLIVDEGHRIKNMKCRLIRELKRFNADNKLLLTGTPLQNNLSELWSLLNFLLPDVFDDLKSFESWFDITSLSETAEDIIAKEREQNVLHMLHQILTPFLLRRLKSDVALEVPPKREVVVYAPLSKKQEIFYTAIVNRTIANMFGSSEKETIELSPTGRPKRRTRKSINYSKIDDFPNELEKLISQIQPEVDRERAVVEVNIPVESEVNLKLQNIMMLLRKCCNHPYLIEYPIDPVTQEFKIDEELVTNSGKFLILDRMLPELKKRGHKVLLFSQMTSMLDILMDYCHLRDFNFSRLDGSMSYSEREKNMHSFNTDPEVFIFLVSTRAGGLGINLTAADTVIIYDSDWNPQSDLQAQDRCHRIGQTKPVVVYRLVTANTIDQKIVERAAAKRKLEKLIIHKNHFKGGQSGLNLSKNFLDPKELMELLKSRDYEREIKGSREKVISDKDLELLLDRSDLIDQMNASGPIKEKMGIFKILENSEDSSPECLF", "length": 838 }, "evidence": [ { "id": "A0A8V0ZSJ4", "url": "https://omabrowser.org/oma/group/A0A8V0ZSJ4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9XFH4-1", "protein_name": "Chromatin remodeling protein DDM1", "gene_name": "DDM1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MVSLRSRKVIPASEMVSDGKTEKDASGDSPTSVLNEEENCEEKSVTVVEEEILLAKNGDSSLISEAMAQEEEQLLKLREDEEKANNAGSAVAPNLNETQFTKLDELLTQTQLYSEFLLEKMEDITINGIESESQKAEPEKTGRGRKRKAASQYNNTKAKRAVAAMISRSKEDGETINSDLTEEETVIKLQNELCPLLTGGQLKSYQLKGVKWLISLWQNGLNGILADQMGLGKTIQTIGFLSHLKGNGLDGPYLVIAPLSTLSNWFNEIARFTPSINAIIYHGDKNQRDELRRKHMPKTVGPKFPIVITSYEVAMNDAKRILRHYPWKYVVIDEGHRLKNHKCKLLRELKHLKMDNKLLLTGTPLQNNLSELWSLLNFILPDIFTSHDEFESWFDFSEKNKNEATKEEEEKRRAQVVSKLHGILRPFILRRMKCDVELSLPRKKEIIMYATMTDHQKKFQEHLVNNTLEAHLGENAIRGQGWKGKLNNLVIQLRKNCNHPDLLQGQIDGSYLYPPVEEIVGQCGKFRLLERLLVRLFANNHKVLIFSQWTKLLDIMDYYFSEKGFEVCRIDGSVKLDERRRQIKDFSDEKSSCSIFLLSTRAGGLGINLTAADTCILYDSDWNPQMDLQAMDRCHRIGQTKPVHVYRLSTAQSIETRVLKRAYSKLKLEHVVIGQGQFHQERAKSSTPLEEEDILALLKEDETAEDKLIQTDISDADLDRLLDRSDLTITAPGETQAAEAFPVKGPGWEVVLPSSGGMLSSLNS", "length": 764 }, "evidence": [ { "id": "A0A8V0ZSJ4", "url": "https://omabrowser.org/oma/group/A0A8V0ZSJ4/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 8, "go_terms": [ { "name": "pericentric heterochromatin formation", "id": "GO:0031508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031508", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSJ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSJ4" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSJ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSJ4" } ], "pmid": "" }, { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSJ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSJ4" } ], "pmid": "" }, { "name": "kidney development", "id": "GO:0001822", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001822", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSJ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSJ4" } ], "pmid": "" }, { "name": "double-strand break repair via homologous recombination", "id": "GO:0000724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000724", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSJ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSJ4" } ], "pmid": "" }, { "name": "lymphocyte proliferation", "id": "GO:0046651", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046651", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSJ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSJ4" } ], "pmid": "" }, { "name": "DNA methylation-dependent constitutive heterochromatin formation", "id": "GO:0006346", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006346", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSJ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSJ4" } ], "pmid": "" }, { "name": "negative regulation of gene expression via chromosomal CpG island methylation", "id": "GO:0044027", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044027", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSJ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSJ4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSJ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSJ4" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSJ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSJ4" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSJ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSJ4" } ], "pmid": "" }, { "name": "helicase activity", "id": "GO:0004386", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004386", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSJ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSJ4" } ], "pmid": "" }, { "name": "chromatin-protein adaptor activity", "id": "GO:0140463", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140463", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSJ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSJ4" } ], "pmid": "" }, { "name": "ATP-dependent chromatin remodeler activity", "id": "GO:0140658", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140658", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSJ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSJ4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSJ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSJ4" } ], "pmid": "" }, { "name": "site of double-strand break", "id": "GO:0035861", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035861", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSJ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSJ4" } ], "pmid": "" }, { "name": "pericentric heterochromatin", "id": "GO:0005721", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005721", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSJ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSJ4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 136, "end_pos": 138, "annotation": "n_glycosylation_sequon" }, { "start_pos": 483, "end_pos": 485, "annotation": "n_glycosylation_sequon" }, { "start_pos": 521, "end_pos": 523, "annotation": "n_glycosylation_sequon" }, { "start_pos": 532, "end_pos": 534, "annotation": "n_glycosylation_sequon" }, { "start_pos": 681, "end_pos": 683, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "13065", "name": "", "equation": "ATP + H2O = ADP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZC95-1", "A0A1D5PHB6-1", "A0A8V0XJV9-1", "A0A8V0ZFN9-1", "A0A1D5PIN7-1", "A0A8V0XT73-1", "A0A8V0XZB8-1", "A0A8V1AJ43-1", "A0A8V0ZU49-1", "P53478-1", "Q5F485-1", "Q5ZHZ0-1", "Q5ZI74-1", "Q5ZIW1-1", "Q5ZKB9-1", "Q5ZM36-1", "Q5ZMN2-1", "A0A8V0XLC7-1", "F1NFJ0-1", "A0A8V0YT68-1", "A0A1D5NTY5-1", "A0A8V0YU49-1", "A0A8V0YHC8-1", "A0A8V0ZPN6-1", "Q5ZJF6-1", "Q5ZKB7-1", "Q8JFP1-1", "A0A8V0YUW3-1", "Q5ZLN8-1", "E1BY42-1", "F1N8Z4-1", "F1NHI3-1", "A0A8V0XI26-1", "A0A8V0XEC4-1", "A0A8V0Y1J8-1", "A0A8V0Y242-1", "A0A8V0X9Z6-1", "A0A8V0Z289-1", "A0A8V0YFB8-1", "A0A8V0YFG2-1", "A0A8V0YNF9-1", "F1N991-1", "A0A8V0ZZF5-1", "A0A8V1ACD8-1", "A0A8V0ZUT3-1", "A0A8V0ZNU6-1", "A0A1D5P5I0-1", "A0A8V0ZZK3-1", "A0A8V1A3M1-1", "A0A8V1AJY9-1", "A0A8V1A712-1", "A0A8V1A7M6-1", "A0A3S5ZPN3-1", "A0A8V1A4V3-1", "A0A8V1AER6-1", "A0A8V1AL41-1", "A0A8V1A5D6-1", "A0A1D5PRR9-1", "A0A8V0Y0A4-1", "Q5ZKK7-1", "A0A8V1AFG8-1", "A0A8V0ZWH7-1", "A0A8V0YLM0-1", "A0A8V0ZNW3-1", "F1ND48-1", "F1NQJ3-1", "P08023-1", "P60706-1", "P63270-1", "P68034-1", "P68139-1", "Q5ZJT0-1", "Q5ZMQ2-1", "Q90593-1", "Q92058-1", "Q9I920-1", "Q90WU3-1", "A0A8V0ZVY2-1", "A0A8V0ZPM1-1", "Q3YK19-1", "E1BSC0-1", "A0A8V0X9Y7-1", "Q5ZM98-1", "F1NZ23-1", "A0A8V0YUG9-1", "F1NN44-1", "P08110-1", "F1NTD6-1", "A0A8V0Z655-1", "A0A8V1ALH0-1", "B6ZLK2-1", "A0A8V0YLC1-1", "Q06A37-1", "A0A8V0YGQ1-1", "A0A1D5PD32-1", "Q6EE31-1", "A0A8V0XX13-1", "A0A8V0YCY8-1", "A0A8V0Z5P2-1", "A0A8V0ZUQ0-1", "A0A8V1ADZ7-1", "A0A8V0XG98-1", "A0A8V0ZR10-1", "A0A8V1AFJ9-1", "Q5ZJ54-1", "Q5ZJK8-1", "A0A8V0Y005-1", "A0A8V0YAA4-1", "A0A8V0XGV3-1", "A0A8V0X600-1", "Q5ZM73-1", "Q5ZM83-1", "A0A8V0ZUR5-1", "A0A8V0ZE45-1", "A0A8V0ZEN5-1", "F1NA92-1", "A0A8V0ZTR5-1", "A0A8V1A7P4-1", "A0A8V1AIK2-1", "F1P5C0-1", "A0A8V0XHD1-1", "A0A8V0X655-1", "A0A8V0XMP8-1", "A0A8V0YUC5-1", "A0A8V0Z1F9-1", "A0A8V0Z659-1", "A0A8V0YRH6-1", "A0A8V0ZS56-1", "I0IUP3-1", "I0IUP4-1", "O93257-1", "O93295-1", "A0A8V0ZIP8-1", "Q9DG67-1", "P37383-1", "Q5ZKG3-1", "P79784-1", "A0A1D5PS27-1", "A0A1D5PVS9-1", "A0A8V1AE46-1", "A0A8V1A8Y2-1", "A0A8V1AKU6-1", "O12944-1", "A0A8V0YQS3-1", "A0A8V0Z2M8-1" ], "evidence": [ { "id": "13065", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/13065" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5NTY5", "gene_name": "LOC430766", "activity": [ { "ec_number": "3.6.4.6", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5NTY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NTY5" } ] }, { 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"https://www.uniprot.org/uniprotkb/A0A1D5PD32" } ] } ] }, { "uniprot_ac": "A0A1D5PHB6", "gene_name": "DHX36", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5PHB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PHB6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A1D5PHB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PHB6" } ] } ] }, { "uniprot_ac": "A0A1D5PIN7", "gene_name": "DHX30", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5PIN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PIN7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A1D5PIN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PIN7" } ] } ] }, { "uniprot_ac": "A0A1D5PRR9", "gene_name": "FANCM", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5PRR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRR9" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A1D5PRR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRR9" } ] } ] }, { "uniprot_ac": "A0A1D5PS27", "gene_name": "ENTPD2", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "A0A1D5PS27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PS27" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "A0A1D5PS27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PS27" } ] } ] }, { "uniprot_ac": "A0A1D5PVS9", "gene_name": "ENTPD3", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "A0A1D5PVS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PVS9" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "A0A1D5PVS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PVS9" } ] } ] }, { "uniprot_ac": "A0A3S5ZPN3", "gene_name": "DDX5", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3S5ZPN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPN3" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A3S5ZPN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPN3" } ] } ] }, { "uniprot_ac": "A0A8V0X600", "gene_name": "DDX43", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0X600", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X600" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0X600", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X600" } ] } ] }, { "uniprot_ac": "A0A8V0X655", "gene_name": "DHX32", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0X655", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X655" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0X655", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X655" } ] } ] }, { "uniprot_ac": "A0A8V0X9Y7", "gene_name": "CFTR", "activity": [ { "ec_number": "5.6.1.6", "activity": "ATP + H2O + closed Cl(-) channel = ADP + phosphate + open Cl(-) channel.", "evidence": [ { "id": "A0A8V0X9Y7", "database": "UniProtKB", "url": 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"gene_name": "AQR", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XHD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XHD1" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0XHD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XHD1" } ] } ] }, { "uniprot_ac": "A0A8V0XI26", "gene_name": "DDX1", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XI26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XI26" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0XI26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XI26" } ] } ] }, { "uniprot_ac": "A0A8V0XJV9", "gene_name": "SPATA5", "activity": [ { "ec_number": "3.6.4.6", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XJV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJV9" } ] }, { "ec_number": "3.6.4.6", "activity": "", "evidence": [ { "id": "A0A8V0XJV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJV9" } ] }, { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XJV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJV9" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "A0A8V0XJV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJV9" } ] } ] }, { "uniprot_ac": "A0A8V0XLC7", "gene_name": "MCM4", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XLC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLC7" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0A8V0XLC7", "database": 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"ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0Y005", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y005" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "A0A8V0Y005", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y005" } ] } ] }, { "uniprot_ac": "A0A8V0Y0A4", "gene_name": "AK6", "activity": [ { "ec_number": "2.7.4.3", "activity": "AMP + ATP = 2 ADP.", "evidence": [ { "id": "A0A8V0Y0A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y0A4" } ] }, { "ec_number": "2.7.4.3", "activity": "", "evidence": [ { "id": "A0A8V0Y0A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y0A4" } ] } ] }, { "uniprot_ac": "A0A8V0Y1J8", "gene_name": "YTHDC2", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0Y1J8", "database": "UniProtKB", "url": 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"activity": "", "evidence": [ { "id": "Q8JFP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8JFP1" } ] } ] }, { "uniprot_ac": "Q90593", "gene_name": "HSPA5", "activity": [ { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q90593", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q90593" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "Q90593", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q90593" } ] } ] }, { "uniprot_ac": "Q90WU3", "gene_name": "DDX1", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q90WU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q90WU3" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "Q90WU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q90WU3" } ] } ] }, { "uniprot_ac": "Q92058", "gene_name": "ALPL", "activity": [ { "ec_number": "3.1.3.1", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "Q92058", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q92058" } ] }, { "ec_number": "3.1.3.1", "activity": "", "evidence": [ { "id": "Q92058", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q92058" } ] } ] }, { "uniprot_ac": "Q9DG67", "gene_name": "RAD54B", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "Q9DG67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9DG67" } ] } ] }, { "uniprot_ac": "Q9I920", "gene_name": "BLM", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q9I920", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9I920" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "Q9I920", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9I920" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZSJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSJ4" }, { "id": "PS51192", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51192" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Helicase ATP-binding", "eco_id": "ECO_0000259", "start_pos": 233, "end_pos": 401, "start_aa": "Arg", "end_aa": "Asp", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZSJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSJ4" }, { "id": "PS51194", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51194" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Helicase C-terminal", "eco_id": "ECO_0000259", "start_pos": 602, "end_pos": 752, "start_aa": "Leu", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 136, "end_pos": 138 }, { "start_pos": 483, "end_pos": 485 }, { "start_pos": 521, "end_pos": 523 }, { "start_pos": 532, "end_pos": 534 }, { "start_pos": 681, "end_pos": 683 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", 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"evidence": [ { "id": "A0A8V0ZSC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSC2" } ] }, { "name": "TANC2", "type": "synonym", "evidence": [ { "id": "XP_015154872", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015154872" } ] } ], "protein_names": [ { "name": "Tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2", "type": "synonym", "evidence": [ { "id": "A0A8V0ZSC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSC2/entry#names_and_taxonomy" } ] }, { "name": "protein TANC2 isoform X10", "type": "synonym", "evidence": [ { "id": "XP_015154872", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015154872" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052558.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015154872.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015154872", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015154872" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSC2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TANC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSC2", "locus": { "chromosome": "27", "start_pos": 2284016, "end_pos": 2114079, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010023245", "url": "https://www.ensembl.org/id/ENSGALG00010023245" } ] } } ], "crossref": [ { "id": "419951", "url": "https://www.ncbi.nlm.nih.gov/gene/419951", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019734", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019734", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050889", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050889", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058018", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058018", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058056", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058056", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "CMLASSC", "url": "https://omabrowser.org/oma/group/CMLASSC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZM23", "url": "https://www.orthodb.org/?gene=A0A8V0ZM23", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24166", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24166", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24166:SF21", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24166:SF21", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00023", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00023", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12796", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12796", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13181", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13181", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13637", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13637", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25520", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25520", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25521", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25521", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015154872", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015154872", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZM23", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM23", "database": "UniProtKB", "categories": [ 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"MFRNSLKMLLTGGKSNRKNRSSDGGSEEPPDRRQASVDARQSRSGQGTSTENDCAFEADYAIPPLPVTEGDAEQELGPPPSVDEAANTLMTRLGFLLGEKVTEVQPGPQYSMEVQDENQSSAVTQRISPCSTLTSSTASPPASSPCSTLPPVSTSVPAKDCSYGAVTSPTSTLESRDSGIIATLTSYSENVERTKYGGESSKEMGSGGNLKPWQSQKSSMDSCLYRVDENMTASTYSLNKIPERNLETVLSQSVQSIPLYLMPRPNSVAATSSAHLEDLAYLDEQRHTPLRTSLRMPRQSVAGARTQQDLRVRFAPYRPPDISLKPLLFEVPSITTESVFVGRDWVFHEIDAQLQSSNASVNRGVVIVGNIGFGKTAIISRLVALSCHGTRMRQIASDSPHASPKHVDANRELPLTQPPSAHSSIASGSCPGTPEMRRRQEEAMRRLASQVVAYHYCQADNAYTCLVPEFVHNVAALLCRSPQFVAYREQLLREPHLQSMLSLRSCVQDPMASFRRGILEPLENLHKERKIPDEDFIILIDGLNEAEFHKPDYGDTIVSFLSKMIGKFPSWLKLVVTVRTSLQEIIKLLPFHRIFLDRLEENEAIDQDLQAYILHRIHSSSEIQNNISLNGKMDNTTFGKLSSHLKTLSQGSYLYLKLTFDLIEKGYLVLKSSSYKVVPVSLSEVYLLQCNMKFPTQSSFDRVMPLLNVAVASLHPLTDEHIFQAINAGNIEGTLEWDDFQQRMENLSMFLIKRRDMTRMFVHPSFREWLIWREEGEKTKFLCDPRSGHTLLAFWFSRQEGKLNRQQTIELGHHILKAHIFKGLSKKVGVSSSILQGLWISYSTEGLSMALASLRNLYTPNIKVSRLLILGGANVNYRTEVLNNAPILCVQSHLGYTEMVALLLEFGANVDAASESGLTPLGYAAAAGFLSIVVLLCKKRAKVDHLDKNGQCALVHAALRGHLEVVKFLIQCDWSMAGQQQGVFKKSHAIQQALIAAASMGYTEIVSYLLDLPEKDEEEVERAQINSFDSLWGETALTAAAGRGKLDVCRLLLEQGAAVAQPNRRGVVPLFSAVRQGHWQIVDLLLTHGADVNMADKQGRTPLMMAASEGHLGTVEFLLAQGASISLMDKEGLTALSWACLKGHLAVVRALVENGAATDHADKNGRTPLDLAAFYGDAEVVQFLVDHGAMIEHVDYSGMRPLDRAVGCRNTSVVVTLLKKGAKIGPATWAMATSKPDIMIILLSKLMEEGDMFYKKGKVKEAAQRYQYALKKFPREGFGEDLKTFRELKVSLLLNLSRCRRKMNDFGMAEEFATKALELKPKSYEAYYARARAKRSSRQFAAALEDLNEAIKLCPNNREIQRLLLRVEEECRQVQQQQQQQQQQPPPLPAEPEPEAQHEELYSVQDIFEEEYLEQDVENVSIGLQTESRPNQGLPIIQSPPPSPAHRDSAYISGSPLGSHQVFDFRSNSSVGSPTRQGYQSTSPTLSPTHQNSHYRPSPPHTSPAHQGSSYRFSPPPVGSQGKEYQSPPPSPLRRGPQYRASPPADGMSVYRSQSGSPVRYQQEPSAVSPLPGRPKSPLSKMSQRSFQMPQLPVAVPQQGLRLQPAKAQIVRSNQPSSAVHSSTVIPTGAYSQVAHSMASKYQAAAGEMGVNQSRLVYQGSIGGIVGDSRPVQHVQASLSAGAICQHGGLAKEDLPQRPSSAYRGGMRYSQTPQIGRSQSASYYPMCHSKLDLERSSLPSGQLGSPDVSHLIRRPISVNPSEIKPHPPTPRPLLHSQSVGLRFSPSSNSISSTSNLTPNFRPSASIQQMEIPLKPAYDRACDELSPVSPTQGGYPSEPARSRTTPFMGIIDKTARTQQYPHLHQQNRTWAVSSVDTVISPTSPGNLPQPESFSPPSSISNIAFYNKTNNAQNGHLLEEDYYSPHGMLANGSRGDLLERVTQASSYPDVKVARTLPVAQAYQDNLYRQLSRDSRQGQTSPIKPKRPFVESNV", "length": 1991, "header": "tr|A0A8V0ZSC2-1|A0A8V0ZSC2_CHICK Isoform 1 of Tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 OS=Gallus gallus OX=9031 GN=TANC2 PE=3 SV=1 CANONICAL=A0A8V0ZSC2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZM23-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSC2/entry#A0A8V0ZM23-1", "sequence": { "sequence": "MFRNSLKMLLTGGKSNRKNRSSDGGSEEPPDRRQASVDARQSRSGQGTSTENDCAFEADYAIPPLPVTEGMQQFRIMEGMSRSLPSSPLLTHQSISVRLQPVKKLPAPLRKAKFVESPRIPESELGSPTLSSAQKLDVDAYCPGDAEQELGPPPSVDEAANTLMTRLGFLLGEKVTEVQPGPQYSMEVQDENQSSAVTQRISPCSTLTSSTASPPASSPCSTLPPVSTSVPAKDCSYGAVTSPTSTLESRDSGIIATLTSYSENVERTKYGGESSKEMGSGGNLKPWQSQKSSMDSCLYRVDENMTASTYSLNKIPERNLETVLSQSVQSIPLYLMPRPNSVAATSSAHLEDLAYLDEQRHTPLRTSLRMPRQSVAGARTQQDLRVRFAPYRPPDISLKPLLFEVPSITTESVFVGRDWVFHEIDAQLQSSNASVNRGVVIVGNIGFGKTAIISRLVALSCHGTRMRQIASDSPHASPKHVDANRELPLTQPPSAHSSIASGSCPGTPEMRRRQEEAMRRLASQVVAYHYCQADNAYTCLVPEFVHNVAALLCRSPQFVAYREQLLREPHLQSMLSLRSCVQDPMASFRRGILEPLENLHKERKIPDEDFIILIDGLNEAEFHKPDYGDTIVSFLSKMIGKFPSWLKLVVTVRTSLQEIIKLLPFHRIFLDRLEENEAIDQDLQAYILHRIHSSSEIQNNISLNGKMDNTTFGKLSSHLKTLSQGSYLYLKLTFDLIEKGYLVLKSSSYKVVPVSLSEVYLLQCNMKFPTQSSFDRVMPLLNVAVASLHPLTDEHIFQAINAGNIEGTLEWDDFQQRMENLSMFLIKRRDMTRMFVHPSFREWLIWREEGEKTKFLCDPRSGHTLLAFWFSRQEGKLNRQQTIELGHHILKAHIFKGLSKKVGVSSSILQGLWISYSTEGLSMALASLRNLYTPNIKVSRLLILGGANVNYRTEVLNNAPILCVQSHLGYTEMVALLLEFGANVDAASESGLTPLGYAAAAGFLSIVVLLCKKRAKVDHLDKNGQCALVHAALRGHLEVVKFLIQCDWSMAGQQQGVFKKSHAIQQALIAAASMGYTEIVSYLLDLPEKDEEEVERAQINSFDSLWGETALTAAAGRGKLDVCRLLLEQGAAVAQPNRRGVVPLFSAVRQGHWQIVDLLLTHGADVNMADKQGRTPLMMAASEGHLGTVEFLLAQGASISLMDKEGLTALSWACLKGHLAVVRALVENGAATDHADKNGRTPLDLAAFYGDAEVVQFLVDHGAMIEHVDYSGMRPLDRAVGCRNTSVVVTLLKKGAKIGCQTLPSRPRGPATWAMATSKPDIMIILLSKLMEEGDMFYKKGKVKEAAQRYQYALKKFPREGFGEDLKTFRELKVSLLLNLSRCRRKMNDFGMAEEFATKALELKPKSYEAYYARARAKRSSRQFAAALEDLNEAIKLCPNNREIQRLLLRVEEECRQVQQQQQQQQQQPPPLPAEPEPEAQHEELYSVQDIFEEEYLEQDVENVSIGLQTESRPNQGLPIIQSPPPSPAHRDSAYISGSPLGSHQVFDFRSNSSVGSPTRQGYQSTSPTLSPTHQNSHYRPSPPHTSPAHQGSSYRFSPPPVGSQGKEYQSPPPSPLRRGPQYRASPPADGMSVYRSQSGSPVRYQQEPSAVSPLPGRPKSPLSKMSQRSFQMPQLPVAVPQQGLRLQPAKAQIVRSNQPSSAVHSSTVIPTGAYSQVAHSMASKYQAAAGEMGVNQSRLVYQGSIGGIVGDSRPVQHVQASLSAGAICQHGGLAKEDLPQRPSSAYRGGMRYSQTPQIGRSQSASYYPMCHSKLDLERSSLPSGQLGSPDVSHLIRRPISVNPSEIKPHPPTPRPLLHSQSVGLRFSPSSNSISSTSNLTPNFRPSASIQQMEIPLKPAYDRACDELSPVSPTQGGYPSEPARSRTTPFMGIIDKTARTQQYPHLHQQNRTWAVSSVDTVISPTSPGNLPQPESFSPPSSISNIAFYNKTNNAQNGHLLEEDYYSPHGMLANGSRGDLLERVTQASSYPDVKVARTLPVAQAYQDNLYRQLSRDSRQGQTSPIKPKRPFVESNV", "length": 2075, "header": "tr|A0A8V0ZM23-1|A0A8V0ZM23_CHICK Computationally mapped isoform of Tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 OS=Gallus gallus OX=9031 GN=TANC2 PE=3 SV=1 CANONICAL=A0A8V0ZSC2-1" }, "locus": { "chromosome": "27", "start_pos": 2283012, "end_pos": 2163831, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056688.1", "url": "https://www.ensembl.org/id/ENSGALT00010056688.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034430.1", "url": "https://www.ensembl.org/id/ENSGALP00010034430.1" } ] } }, { "isoform_ac": "A0A8V0ZSA0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSC2/entry#A0A8V0ZSA0-1", "sequence": { "sequence": "MQCWLDVVCLDFSKAFAPLRKAKFVESPRIPESELGSPTLSSAQKLDVDAYCPGDAEQELGPPPSVDEAANTLMTRLGFLLGEKVTEVQPGPQYSMEVQDENQSSAVTQRISPCSTLTSSTASPPASSPCSTLPPVSTSVPAKDCSYGAVTSPTSTLESRDSGIIATLTSYSENVERTKYGGESSKEMGSGGNLKPWQSQKSSMDSCLYRVDENMTASTYSLNKIPERNLETVLSQSVQSIPLYLMPRPNSVAATSSAHLEDLAYLDEQRHTPLRTSLRMPRQSVAGARTQQDLRVRFAPYRPPDISLKPLLFEVPSITTESVFVGRDWVFHEIDAQLQSSNASVNRGVVIVGNIGFGKTAIISRLVALSCHGTRMRQIASDSPHASPKHVDANRELPLTQPPSAHSSIASGSCPGTPEMRRRQEEAMRRLASQVVAYHYCQADNAYTCLVPEFVHNVAALLCRSPQFVAYREQLLREPHLQSMLSLRSCVQDPMASFRRGILEPLENLHKERKIPDEDFIILIDGLNEAEFHKPDYGDTIVSFLSKMIGKFPSWLKLVVTVRTSLQEIIKLLPFHRIFLDRLEENEAIDQDLQAYILHRIHSSSEIQNNISLNGKMDNTTFGKLSSHLKTLSQGSYLYLKLTFDLIEKGYLVLKSSSYKVVPVSLSEVYLLQCNMKFPTQSSFDRVMPLLNVAVASLHPLTDEHIFQAINAGNIEGTLEWDDFQQRMENLSMFLIKRRDMTRMFVHPSFREWLIWREEGEKTKFLCDPRSGHTLLAFWFSRQEGKLNRQQTIELGHHILKAHIFKGLSKKVGVSSSILQGLWISYSTEGLSMALASLRNLYTPNIKVSRLLILGGANVNYRTEVLNNAPILCVQSHLGYTEMVALLLEFGANVDAASESGLTPLGYAAAAGFLSIVVLLCKKRAKVDHLDKNGQCALVHAALRGHLEVVKFLIQCDWSMAGQQQGVFKKSHAIQQALIAAASMGYTEIVSYLLDLPEKDEEEVERAQINSFDSLWGETALTAAAGRGKLDVCRLLLEQGAAVAQPNRRGVVPLFSAVRQGHWQIVDLLLTHGADVNMADKQGRTPLMMAASEGHLGTVEFLLAQGASISLMDKEGLTALSWACLKGHLAVVRALVENGAATDHADKNGRTPLDLAAFYGDAEVVQFLVDHGAMIEHVDYSGMRPLDRAVGCRNTSVVVTLLKKGAKIGPATWAMATSKPDIMIILLSKLMEEGDMFYKKGKVKEAAQRYQYALKKFPREGFGEDLKTFRELKVSLLLNLSRCRRKMNDFGMAEEFATKALELKPKSYEAYYARARAKRSSRQFAAALEDLNEAIKLCPNNREIQRLLLRVEEECRQVQQQQQQQQQQPPPLPAEPEPEAQHEELYSVQDIFEEEYLEQDVENVSIGLQTESRPNQGLPIIQSPPPSPAHRDSAYISGSPLGSHQVFDFRSNSSVGSPTRQGYQSTSPTLSPTHQNSHYRPSPPHTSPAHQGSSYRFSPPPVGSQGKEYQSPPPSPLRRGPQYRASPPADGMSVYRSQSGSPVRYQQEPSAVSPLPGRPKSPLSKMSQRSFQMPQLPVAVPQQGLRLQPAKAQIVRSNQPSSAVHSSTVIPTGAYSQVAHSMASKYQAAAGEMGVNQSRLVYQGSIGGIVGDSRPVQHVQASLSAGAICQHGGLAKEDLPQRPSSAYRGGMRYSQTPQIGRSQSASYYPMCHSKLDLERSSLPSGQLGSPDVSHLIRRPISVNPSEIKPHPPTPRPLLHSQSVGLRFSPSSNSISSTSNLTPNFRPSASIQQMEIPLKPAYDRACDELSPVSPTQGGYPSEPARSRTTPFMGIIDKTARTQQYPHLHQQNRTWAVSSVDTVISPTSPGNLPQPESFSPPSSISNIAFYNKTNNAQNGHLLEEDYYSPHGMLANGSRGDLLERVTQASSYPDVKVARTLPVAQAYQDNLYRQLSRDSRQGQTSPIKPKRPFVESNV", "length": 1975, "header": "tr|A0A8V0ZSA0-1|A0A8V0ZSA0_CHICK Computationally mapped isoform of Tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 OS=Gallus gallus OX=9031 GN=TANC2 PE=3 SV=1 CANONICAL=A0A8V0ZSC2-1" }, "locus": { "chromosome": "27", "start_pos": 2283012, "end_pos": 2192352, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056678.1", "url": "https://www.ensembl.org/id/ENSGALT00010056678.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034421.1", "url": "https://www.ensembl.org/id/ENSGALP00010034421.1" } ] } }, { "isoform_ac": "A0A8V0ZSA6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSC2/entry#A0A8V0ZSA6-1", "sequence": { "sequence": "MFRNSLKMLLTGGKSNRKNRSSGTSTENDCAFEADYAIPPLPVTEGMQQFRIMEGMSRSLPSSPLLTHQSISVRLQPVKKLPAPLRKAKFVESPRIPESELGSPTLSSAQKLDVDAYCPGDAEQELGPPPSVDEAANTLMTRLGFLLGEKVTEVQPGPQYSMEVQDENQSSAVTQRISPCSTLTSSTASPPASSPCSTLPPVSTSVPAKDCSYGAVTSPTSTLESRDSGIIATLTSYSENVERTKYGGESSKEMGSGGNLKPWQSQKSSMDSCLYRVDENMTASTYSLNKIPERNLETVLSQSVQSIPLYLMPRPNSVAATSSAHLEDLAYLDEQRHTPLRTSLRMPRQSVAGARTQQDLRVRFAPYRPPDISLKPLLFEVPSITTESVFVGRDWVFHEIDAQLQSSNASVNRGVVIVGNIGFGKTAIISRLVALSCHGTRMRQIASDSPHASPKHVDANRELPLTQPPSAHSSIASGSCPGTPEMRRRQEEAMRRLASQVVAYHYCQADNAYTCLVPEFVHNVAALLCRSPQFVAYREQLLREPHLQSMLSLRSCVQDPMASFRRGILEPLENLHKERKIPDEDFIILIDGLNEAEFHKPDYGDTIVSFLSKMIGKFPSWLKLVVTVRTSLQEIIKLLPFHRIFLDRLEENEAIDQDLQAYILHRIHSSSEIQNNISLNGKMDNTTFGKLSSHLKTLSQGSYLYLKLTFDLIEKGYLVLKSSSYKVVPVSLSEVYLLQCNMKFPTQSSFDRVMPLLNVAVASLHPLTDEHIFQAINAGNIEGTLEWDDFQQRMENLSMFLIKRRDMTRMFVHPSFREWLIWREEGEKTKFLCDPRSGHTLLAFWFSRQEGKLNRQQTIELGHHILKAHIFKGLSKKVGVSSSILQGLWISYSTEGLSMALASLRNLYTPNIKVSRLLILGGANVNYRTEVLNNAPILCVQSHLGYTEMVALLLEFGANVDAASESGLTPLGYAAAAGFLSIVVLLCKKRAKVDHLDKNGQCALVHAALRGHLEVVKFLIQCDWSMAGQQQGVFKKSHAIQQALIAAASMGYTEIVSYLLDLPEKDEEEVERAQINSFDSLWGETALTAAAGRGKLDVCRLLLEQGAAVAQPNRRGVVPLFSAVRQGHWQIVDLLLTHGADVNMADKQGRTPLMMAASEGHLGTVEFLLAQGASISLMDKEGLTALSWACLKGHLAVVRALVENGAATDHADKNGRTPLDLAAFYGDAEVVQFLVDHGAMIEHVDYSGMRPLDRAVGCRNTSVVVTLLKKGAKIGCQTLPSRPRGPATWAMATSKPDIMIILLSKLMEEGDMFYKKGKVKEAAQRYQYALKKFPREGFGEDLKTFRELKVSLLLNLSRCRRKMNDFGMAEEFATKALELKPKSYEAYYARARAKRSSRQFAAALEDLNEAIKLCPNNREIQRLLLRVEEECRQVQQQQQQQQQQPPPLPAEPEPEAQHEELYSVQDIFEEEYLEQDVENVSIGLQTESRPNQGLPIIQSPPPSPAHRDSAYISGSPLGSHQVFDFRSNSSVGSPTRQGYQSTSPTLSPTHQNSHYRPSPPHTSPAHQGSSYRFSPPPVGSQGKEYQSPPPSPLRRGPQYRASPPADGMSVYRSQSGSPVRYQQEPSAVSPLPGRPKSPLSKMSQRSFQMPQLPVAVPQQGLRLQPAKAQIVRSNQPSSAVHSSTVIPTGAYSQVAHSMASKYQAAAGEMGVNQSRLVYQGSIGGIVGDSRPVQHVQASLSAGAICQHGGLAKEDLPQRPSSAYRGGMRYSQTPQIGRSQSASYYPMCHSKLDLERSSLPSGQLGSPDVSHLIRRPISVNPSEIKPHPPTPRPLLHSQSVGLRFSPSSNSISSTSNLTPNFRPSASIQQMEIPLKPAYDRACDELSPVSPTQGGYPSEPARSRTTPFMGIIDKTARTQQYPHLHQQNRTWAVSSVDTVISPTSPGNLPQPESFSPPSSISNIAFYNKTNNAQNGHLLEEDYYSPHGMLANGSRGDLLERVTQASSYPDVKVARTLPVAQAYQDNLYRQLSRDSRQGQTSPIKPKRPFVESNV", "length": 2051, "header": "tr|A0A8V0ZSA6-1|A0A8V0ZSA6_CHICK Computationally mapped isoform of Tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 OS=Gallus gallus OX=9031 GN=TANC2 PE=3 SV=1 CANONICAL=A0A8V0ZSC2-1" }, "locus": { "chromosome": "27", "start_pos": 2283012, "end_pos": 2163831, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056685.1", "url": "https://www.ensembl.org/id/ENSGALT00010056685.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034427.1", "url": "https://www.ensembl.org/id/ENSGALP00010034427.1" } ] } }, { "isoform_ac": "A0A8V0ZSC2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSC2/entry#A0A8V0ZSC2-1", "sequence": { "sequence": "MFRNSLKMLLTGGKSNRKNRSSDGGSEEPPDRRQASVDARQSRSGQGTSTENDCAFEADYAIPPLPVTEGDAEQELGPPPSVDEAANTLMTRLGFLLGEKVTEVQPGPQYSMEVQDENQSSAVTQRISPCSTLTSSTASPPASSPCSTLPPVSTSVPAKDCSYGAVTSPTSTLESRDSGIIATLTSYSENVERTKYGGESSKEMGSGGNLKPWQSQKSSMDSCLYRVDENMTASTYSLNKIPERNLETVLSQSVQSIPLYLMPRPNSVAATSSAHLEDLAYLDEQRHTPLRTSLRMPRQSVAGARTQQDLRVRFAPYRPPDISLKPLLFEVPSITTESVFVGRDWVFHEIDAQLQSSNASVNRGVVIVGNIGFGKTAIISRLVALSCHGTRMRQIASDSPHASPKHVDANRELPLTQPPSAHSSIASGSCPGTPEMRRRQEEAMRRLASQVVAYHYCQADNAYTCLVPEFVHNVAALLCRSPQFVAYREQLLREPHLQSMLSLRSCVQDPMASFRRGILEPLENLHKERKIPDEDFIILIDGLNEAEFHKPDYGDTIVSFLSKMIGKFPSWLKLVVTVRTSLQEIIKLLPFHRIFLDRLEENEAIDQDLQAYILHRIHSSSEIQNNISLNGKMDNTTFGKLSSHLKTLSQGSYLYLKLTFDLIEKGYLVLKSSSYKVVPVSLSEVYLLQCNMKFPTQSSFDRVMPLLNVAVASLHPLTDEHIFQAINAGNIEGTLEWDDFQQRMENLSMFLIKRRDMTRMFVHPSFREWLIWREEGEKTKFLCDPRSGHTLLAFWFSRQEGKLNRQQTIELGHHILKAHIFKGLSKKVGVSSSILQGLWISYSTEGLSMALASLRNLYTPNIKVSRLLILGGANVNYRTEVLNNAPILCVQSHLGYTEMVALLLEFGANVDAASESGLTPLGYAAAAGFLSIVVLLCKKRAKVDHLDKNGQCALVHAALRGHLEVVKFLIQCDWSMAGQQQGVFKKSHAIQQALIAAASMGYTEIVSYLLDLPEKDEEEVERAQINSFDSLWGETALTAAAGRGKLDVCRLLLEQGAAVAQPNRRGVVPLFSAVRQGHWQIVDLLLTHGADVNMADKQGRTPLMMAASEGHLGTVEFLLAQGASISLMDKEGLTALSWACLKGHLAVVRALVENGAATDHADKNGRTPLDLAAFYGDAEVVQFLVDHGAMIEHVDYSGMRPLDRAVGCRNTSVVVTLLKKGAKIGPATWAMATSKPDIMIILLSKLMEEGDMFYKKGKVKEAAQRYQYALKKFPREGFGEDLKTFRELKVSLLLNLSRCRRKMNDFGMAEEFATKALELKPKSYEAYYARARAKRSSRQFAAALEDLNEAIKLCPNNREIQRLLLRVEEECRQVQQQQQQQQQQPPPLPAEPEPEAQHEELYSVQDIFEEEYLEQDVENVSIGLQTESRPNQGLPIIQSPPPSPAHRDSAYISGSPLGSHQVFDFRSNSSVGSPTRQGYQSTSPTLSPTHQNSHYRPSPPHTSPAHQGSSYRFSPPPVGSQGKEYQSPPPSPLRRGPQYRASPPADGMSVYRSQSGSPVRYQQEPSAVSPLPGRPKSPLSKMSQRSFQMPQLPVAVPQQGLRLQPAKAQIVRSNQPSSAVHSSTVIPTGAYSQVAHSMASKYQAAAGEMGVNQSRLVYQGSIGGIVGDSRPVQHVQASLSAGAICQHGGLAKEDLPQRPSSAYRGGMRYSQTPQIGRSQSASYYPMCHSKLDLERSSLPSGQLGSPDVSHLIRRPISVNPSEIKPHPPTPRPLLHSQSVGLRFSPSSNSISSTSNLTPNFRPSASIQQMEIPLKPAYDRACDELSPVSPTQGGYPSEPARSRTTPFMGIIDKTARTQQYPHLHQQNRTWAVSSVDTVISPTSPGNLPQPESFSPPSSISNIAFYNKTNNAQNGHLLEEDYYSPHGMLANGSRGDLLERVTQASSYPDVKVARTLPVAQAYQDNLYRQLSRDSRQGQTSPIKPKRPFVESNV", "length": 1991, "header": "tr|A0A8V0ZSC2-1|A0A8V0ZSC2_CHICK Isoform 1 of Tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 OS=Gallus gallus OX=9031 GN=TANC2 PE=3 SV=1 CANONICAL=A0A8V0ZSC2-1" }, "locus": { "chromosome": "27", "start_pos": 2283012, "end_pos": 2163831, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056700.1", "url": "https://www.ensembl.org/id/ENSGALT00010056700.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034442.1", "url": "https://www.ensembl.org/id/ENSGALP00010034442.1" } ] } }, { "isoform_ac": "A0A8V0ZUB0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSC2/entry#A0A8V0ZUB0-1", "sequence": { "sequence": "MFRNSLKMLLTGGKSNRKNRSSDGGSEEPPDRRQASVDARQSRSGQGTSTENDCAFEADYAIPPLPVTEGMQQFRIMEGMSRSLPSSPLLTHQSISVRLQPVKKLPAPLRKAKFVESPRIPESELGSPTLSSAQKLDVDAYCPGDAEQELGPPPSVDEAANTLMTRLGFLLGEKVTEVQPGPQYSMEVQDENQSSAVTQRISPCSTLTSSTASPPASSPCSTLPPVSTSVPAKDCSYGAVTSPTSTLESRDSGIIATLTSYSENVERTKYGGESSKEMGSGGNLKPWQSQKSSMDSCLYRVDENMTASTYSLNKIPERNLETVLSQSVQSIPLYLMPRPNSVAATSSAHLEDLAYLDEQRHTPLRTSLRMPRQSVAGARTQQDLRVRFAPYRPPDISLKPLLFEVPSITTESVFVGRDWVFHEIDAQLQSSNASVNRGVVIVGNIGFGKTAIISRLVALSCHGTRMRQIASDSPHASPKHVDANRELPLTQPPSAHSSIASGSCPGTPEMRRRQEEAMRRLASQVVAYHYCQADNAYTCLVPEFVHNVAALLCRSPQFVAYREQLLREPHLQSMLSLRSCVQDPMASFRRGILEPLENLHKERKIPDEDFIILIDGLNEAEFHKPDYGDTIVSFLSKMIGKFPSWLKLVVTVRTSLQEIIKLLPFHRIFLDRLEENEAIDQDLQAYILHRIHSSSEIQNNISLNGKMDNTTFGKLSSHLKTLSQGSYLYLKLTFDLIEKGYLVLKSSSYKVVPVSLSEVYLLQCNMKFPTQSSFDRVMPLLNVAVASLHPLTDEHIFQAINAGNIEGTLEWDDFQQRMENLSMFLIKRRDMTRMFVHPSFREWLIWREEGEKTKFLCDPRSGHTLLAFWFSRQEGKLNRQQTIELGHHILKAHIFKGLSKKVGVSSSILQGLWISYSTEGLSMALASLRNLYTPNIKVSRLLILGGANVNYRTEVLNNAPILCVQSHLGYTEMVALLLEFGANVDAASESGLTPLGYAAAAGFLSIVVLLCKKRAKVDHLDKNGQCALVHAALRGHLEVVKFLIQCDWSMAGQQQGVFKKSHAIQQALIAAASMGYTEIVSYLLDLPEKDEEEVERAQINSFDSLWGETALTAAAGRGKLDVCRLLLEQGAAVAQPNRRGVVPLFSAVRQGHWQIVDLLLTHGADVNMADKQGRTPLMMAASEGHLGTVEFLLAQGASISLMDKEGLTALSWACLKGHLAVVRALVENGAATDHADKNGRTPLDLAAFYGDAEVVQFLVDHGAMIEHVDYSGMRPLDRAVGCRNTSVVVTLLKKGAKIGPATWAMATSKPDIMIILLSKLMEEGDMFYKKGKVKEAAQRYQYALKKFPREGFGEDLKTFRELKVSLLLNLSRCRRKMNDFGMAEEFATKALELKPKSYEAYYARARAKRSSRQFAAALEDLNEAIKLCPNNREIQRLLLRVEEECRQVQQQQQQQQQQPPPLPAEPEPEAQHEELYSVQDIFEEEYLEQDVENVSIGLQTESRPNQGLPIIQSPPPSPAHRDSAYISGSPLGSHQVFDFRSNSSVGSPTRQGYQSTSPTLSPTHQNSHYRPSPPHTSPAHQGSSYRFSPPPVGSQGKEYQSPPPSPLRRGPQYRASPPADGMSVYRSQSGSPVRYQQEPSAVSPLPGRPKSPLSKMSQRSFQMPQLPVAVPQQGLRLQPAKAQIVRSNQPSSAVHSSTVIPTGAYSQVAHSMASKYQAAAGEMGVNQSRLVYQGSIGGIVGDSRPVQHVQASLSAGAICQHGGLAKEDLPQRPSSAYRGGMRYSQTPQIGRSQSASYYPMCHSKLDLERSSLPSGQLGSPDVSHLIRRPISVNPSEIKPHPPTPRPLLHSQSVGLRFSPSSNSISSTSNLTPNFRPSASIQQMEIPLKPAYDRACDELSPVSPTQGGYPSEPARSRTTPFMGIIDKTARTQQYPHLHQQNRTWAVSSVDTVISPTSPGNLPQPESFSPPSSISNIAFYNKTNNAQNGHLLEEDYYSPHGMLANGSRGDLLERVTQASSYPDVKVARTLPVAQAYQDNLYRQLSRDSRQGQTSPIKPKRPFVESNV", "length": 2065, "header": "tr|A0A8V0ZUB0-1|A0A8V0ZUB0_CHICK Computationally mapped isoform of Tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 OS=Gallus gallus OX=9031 GN=TANC2 PE=3 SV=1 CANONICAL=A0A8V0ZSC2-1" }, "locus": { "chromosome": "27", "start_pos": 2283012, "end_pos": 2163831, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056691.1", "url": "https://www.ensembl.org/id/ENSGALT00010056691.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034434.1", "url": "https://www.ensembl.org/id/ENSGALP00010034434.1" } ] } }, { "isoform_ac": "A0A8V0ZZW3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSC2/entry#A0A8V0ZZW3-1", "sequence": { "sequence": "MFRNSLKMLLTGGKSNRKNRSSGTSTENDCAFEADYAIPPLPVTEAPLRKAKFVESPRIPESELGSPTLSSAQKLDVDAYCPGDAEQELGPPPSVDEAANTLMTRLGFLLGEKVTEVQPGPQYSMEVQDENQSSAVTQRISPCSTLTSSTASPPASSPCSTLPPVSTSVPAKDCSYGAVTSPTSTLESRDSGIIATLTSYSENVERTKYGGESSKEMGSGGNLKPWQSQKSSMDSCLYRVDENMTASTYSLNKIPERNLETVLSQSVQSIPLYLMPRPNSVAATSSAHLEDLAYLDEQRHTPLRTSLRMPRQSVAGARTQQDLRVRFAPYRPPDISLKPLLFEVPSITTESVFVGRDWVFHEIDAQLQSSNASVNRGVVIVGNIGFGKTAIISRLVALSCHGTRMRQIASDSPHASPKHVDANRELPLTQPPSAHSSIASGSCPGTPEMRRRQEEAMRRLASQVVAYHYCQADNAYTCLVPEFVHNVAALLCRSPQFVAYREQLLREPHLQSMLSLRSCVQDPMASFRRGILEPLENLHKERKIPDEDFIILIDGLNEAEFHKPDYGDTIVSFLSKMIGKFPSWLKLVVTVRTSLQEIIKLLPFHRIFLDRLEENEAIDQDLQAYILHRIHSSSEIQNNISLNGKMDNTTFGKLSSHLKTLSQGSYLYLKLTFDLIEKGYLVLKSSSYKVVPVSLSEVYLLQCNMKFPTQSSFDRVMPLLNVAVASLHPLTDEHIFQAINAGNIEGTLEWDDFQQRMENLSMFLIKRRDMTRMFVHPSFREWLIWREEGEKTKFLCDPRSGHTLLAFWFSRQEGKLNRQQTIELGHHILKAHIFKGLSKKVGVSSSILQGLWISYSTEGLSMALASLRNLYTPNIKVSRLLILGGANVNYRTEVLNNAPILCVQSHLGYTEMVALLLEFGANVDAASESGLTPLGYAAAAGFLSIVVLLCKKRAKVDHLDKNGQCALVHAALRGHLEVVKFLIQCDWSMAGQQQGVFKKSHAIQQALIAAASMGYTEIVSYLLDLPEKDEEEVERAQINSFDSLWGETALTAAAGRGKLDVCRLLLEQGAAVAQPNRRGVVPLFSAVRQGHWQIVDLLLTHGADVNMADKQGRTPLMMAASEGHLGTVEFLLAQGASISLMDKEGLTALSWACLKGHLAVVRALVENGAATDHADKNGRTPLDLAAFYGDAEVVQFLVDHGAMIEHVDYSGMRPLDRAVGCRNTSVVVTLLKKGAKIGCQTLPSRPRGPATWAMATSKPDIMIILLSKLMEEGDMFYKKGKVKEAAQRYQYALKKFPREGFGEDLKTFRELKVSLLLNLSRCRRKMNDFGMAEEFATKALELKPKSYEAYYARARAKRSSRQFAAALEDLNEAIKLCPNNREIQRLLLRVEEECRQVQQQQQQQQQQPPPLPAEPEPEAQHEELYSVQDIFEEEYLEQDVENVSIGLQTESRPNQGLPIIQSPPPSPAHRDSAYISGSPLGSHQVFDFRSNSSVGSPTRQGYQSTSPTLSPTHQNSHYRPSPPHTSPAHQGSSYRFSPPPVGSQGKEYQSPPPSPLRRGPQYRASPPADGMSVYRSQSGSPVRYQQEPSAVSPLPGRPKSPLSKMSQRSFQMPQLPVAVPQQGLRLQPAKAQIVRSNQPSSAVHSSTVIPTGAYSQVAHSMASKYQAAAGEMGVNQSRLVYQGSIGGIVGDSRPVQHVQASLSAGAICQHGGLAKEDLPQRPSSAYRGGMRYSQTPQIGRSQSASYYPMCHSKLDLERSSLPSGQLGSPDVSHLIRRPISVNPSEIKPHPPTPRPLLHSQSVGLRFSPSSNSISSTSNLTPNFRPSASIQQMEIPLKPAYDRACDELSPVSPTQGGYPSEPARSRTTPFMGIIDKTARTQQYPHLHQQNRTWAVSSVDTVISPTSPGNLPQPESFSPPSSISNIAFYNKTNNAQNGHLLEEDYYSPHGMLANGSRGDLLERVTQASSYPDVKVARTLPVAQAYQDNLYRQLSRDSRQGQTSPIKPKRPFVESNV", "length": 2014, "header": "tr|A0A8V0ZZW3-1|A0A8V0ZSC2_CHICK Computationally mapped isoform of Tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 OS=Gallus gallus OX=9031 GN=TANC2 PE=3 SV=1 CANONICAL=A0A8V0ZSC2-1" }, "locus": { "chromosome": "27", "start_pos": 2283012, "end_pos": 2163831, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056710.1", "url": "https://www.ensembl.org/id/ENSGALT00010056710.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034452.1", "url": "https://www.ensembl.org/id/ENSGALP00010034452.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1830, "start_aa": "Thr", "end_pos": 1830, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1830", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1881, "start_aa": "Thr", "end_pos": 1881, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1881", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "dendritic spine", "id": "GO:0043197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043197", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSC2" } ], "pmid": "" }, { "name": "postsynapse", "id": "GO:0098794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098794", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSC2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of dendritic spine morphogenesis", "id": "GO:0061001", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061001", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSC2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "structural constituent of postsynaptic density", "id": "GO:0098919", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098919", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSC2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 118, "end_pos": 120, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1210, "end_pos": 1212, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1295, "end_pos": 1297, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1419, "end_pos": 1421, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1468, "end_pos": 1470, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1652, "end_pos": 1654, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1795, "end_pos": 1797, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1866, "end_pos": 1868, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1905, "end_pos": 1907, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1929, "end_pos": 1931, "annotation": "n_glycosylation_sequon" }, { "start_pos": 19, "end_pos": 21, "annotation": "n_glycosylation_sequon" }, { "start_pos": 230, "end_pos": 232, "annotation": "n_glycosylation_sequon" }, { "start_pos": 358, "end_pos": 360, "annotation": "n_glycosylation_sequon" }, { "start_pos": 626, "end_pos": 628, "annotation": "n_glycosylation_sequon" }, { "start_pos": 635, "end_pos": 637, "annotation": "n_glycosylation_sequon" }, { "start_pos": 746, "end_pos": 748, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZSC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSC2" }, { "id": "PF25520", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25520" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "TANC1/2-like AAA+ ATPase lid", "eco_id": "ECO_0000259", "start_pos": 597, "end_pos": 691, "start_aa": "Asp", "end_aa": "Asn", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZSC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSC2" }, { "id": "PF25521", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25521" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "TANC1/2-like winged helix", "eco_id": "ECO_0000259", "start_pos": 693, "end_pos": 845, "start_aa": "Lys", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 1830, 1881 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 118, "end_pos": 120 }, { "start_pos": 1210, "end_pos": 1212 }, { "start_pos": 1295, "end_pos": 1297 }, { "start_pos": 1419, "end_pos": 1421 }, { "start_pos": 1468, "end_pos": 1470 }, { "start_pos": 1652, "end_pos": 1654 }, { "start_pos": 1795, "end_pos": 1797 }, { "start_pos": 1866, "end_pos": 1868 }, { "start_pos": 1905, "end_pos": 1907 }, { "start_pos": 1929, "end_pos": 1931 }, { "start_pos": 19, "end_pos": 21 }, { "start_pos": 230, "end_pos": 232 }, { "start_pos": 358, "end_pos": 360 }, { "start_pos": 626, "end_pos": 628 }, { "start_pos": 635, "end_pos": 637 }, { "start_pos": 746, "end_pos": 748 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": 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"sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NSA8-1", "uniprot_ac": "F1NSA8", "uniprot_id": "F1NSA8_CHICK", "mass": { "chemical_mass": 21001.0, "monoisotopic_mass": 21001.0 }, "refseq": { "ac": "XP_417994", "name": "ras-related protein Rap-1A isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417994" }, "gene_names": [ { "name": "RAP1A", "type": "recommended", "evidence": [ { "id": "F1NSA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NSA8" } ] }, { "name": "RAP1A", "type": "synonym", "evidence": [ { "id": "XP_417994", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417994" } ] } ], "protein_names": [ { "name": "small monomeric GTPase", "type": "recommended", "evidence": [ { "id": "F1NSA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NSA8/entry#names_and_taxonomy" } ] }, { "name": "3.6.5.2", "type": "synonym", "evidence": [ { "id": "F1NSA8", "database": "UniProtKB", "url": 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This record is derived from a genomic sequence (NC_052557.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_417994", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417994" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NSA8", "url": "https://www.uniprot.org/uniprotkb/F1NSA8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RAP1A", "url": "https://www.uniprot.org/uniprotkb/F1NSA8", "locus": {} } ], "crossref": [ { "id": "F1NSA8", "url": "https://alphafold.ebi.ac.uk/entry/F1NSA8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000001476", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000001476", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd04175", "url": 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"PTHR24070", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24070", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00071", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00071", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-170968", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-170968", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-170984", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-170984", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-354192", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-354192", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-354194", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-354194", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-372708", "url": 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"categories": [ "Protein" ] }, { "id": "19669", "url": "https://www.rhea-db.org/rhea/19669", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZWU7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWU7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZWU7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWU7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A229", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A229", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A229-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A229-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A4D1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4D1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A4D1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4D1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NSA8", "url": 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{ "chromosome": "26", "start_pos": 3296006, "end_pos": 3287414, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010061627.1", "url": "https://www.ensembl.org/id/ENSGALT00010061627.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038064.1", "url": "https://www.ensembl.org/id/ENSGALP00010038064.1" } ] } }, { "isoform_ac": "A0A8V1A4D1-1", "url": "https://www.uniprot.org/uniprotkb/F1NSA8/entry#A0A8V1A4D1-1", "sequence": { "sequence": "MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDCQQCMLEILDTAGTEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTEDVPMILVGNKCDLEEERVVGKEQGQNLARQWCNCAFLESSAKSKINVNETSHHSPPLIFYDLVRQINRKTPVEKKKPKKKSCLLL", "length": 192, "header": "tr|A0A8V1A4D1-1|F1NSA8_CHICK Computationally mapped isoform of small monomeric GTPase OS=Gallus gallus OX=9031 GN=RAP1A PE=1 SV=1 CANONICAL=F1NSA8-1" }, "locus": { "chromosome": "26", "start_pos": 3295180, "end_pos": 3287414, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": 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"https://www.ensembl.org/id/ENSGALP00010038051.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:419867", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419867", "resource": "KEGG Pathway" }, { "id": "R-GGA-170968", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-170968", "resource": "Reactome", "description": "Frs2-mediated activation" }, { "id": "R-GGA-170984", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-170984", "resource": "Reactome", "description": "ARMS-mediated activation" }, { "id": "R-GGA-354192", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-354192", "resource": "Reactome", "description": "Integrin signaling" }, { "id": "R-GGA-354194", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-354194", "resource": "Reactome", "description": "GRB2:SOS provides linkage to MAPK signaling for Integrins" }, { "id": "R-GGA-372708", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-372708", "resource": "Reactome", "description": "p130Cas linkage to MAPK signaling for integrins" }, { "id": "R-GGA-381676", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-381676", "resource": "Reactome", "description": "Glucagon-like Peptide-1 (GLP1) regulates insulin secretion" }, { "id": "R-GGA-392517", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-392517", "resource": "Reactome", "description": "Rap1 signalling" }, { "id": "R-GGA-5674135", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5674135", "resource": "Reactome", "description": "MAP2K and MAPK activation" }, { "id": "R-GGA-6798695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798695", "resource": "Reactome", "description": "Neutrophil degranulation" }, { "id": "R-GGA-8875555", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8875555", "resource": "Reactome", "description": "MET activates RAP1 and RAC1" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1TAH5-1", "protein_name": "small monomeric GTPase", "gene_name": "RAP1A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDCQQCMLEILDTAGTEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTEDVPMILVGNKCDLEDERVVGKEQGQNLARQWCNCAFLESSAKSKINVNEIFYDLVRQINRKTPVEKKKPKKKSCLLL", "length": 184 }, "evidence": [ { "id": "F1NSA8", "url": "https://omabrowser.org/oma/group/F1NSA8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "E7FBI4-1", "protein_name": "Ras-related protein Rap-1b", "gene_name": "rap1ab", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTEDVPMILVGNKCDLEDERVVGKEQGQNLARQWNNCAFLESSAKSKINVLDIFYDLVRQINRKTPVEKKKAKKKSNCVLL", "length": 185 }, "evidence": [ { "id": "F1NSA8", "url": "https://omabrowser.org/oma/group/F1NSA8/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "G3IBI0-1", "protein_name": "small monomeric GTPase", "gene_name": "Rap1a", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDCQQCMLEILDTAGTEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTEDVPMILVGNKCDLEDERVVGKEQGQNLARQWCNCAFLESSAKSKINVNEIFYDLVRQINRKTPVEKKKPKKKSCLLL", "length": 184 }, "evidence": [ { "id": "F1NSA8", "url": "https://omabrowser.org/oma/group/F1NSA8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P32252-1", "protein_name": "Ras-like protein rasB", "gene_name": "rasB", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSVSNEYKLVVMGGGGVGKSALTIQFIQNHFIEEYDPTIEDSYRRQCQVDEDTCLLDILDTAGQDDYSAMRDQYMRTGQGFLCVYDVTSRTSFEEINVVREQIIRVKDNDKVPIVLVGNKCDLENLREVTEGEGSELAKSFSVPFLETSAKKRLNVDECFFEVVREIKKSLKEPGRSKKDKKGGILKKFKGGDCLIL", "length": 197 }, "evidence": [ { "id": "F1NSA8", "url": "https://omabrowser.org/oma/group/F1NSA8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "P61224-1", "protein_name": "Ras-related protein Rap-1b", "gene_name": "RAP1B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDAQQCMLEILDTAGTEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTDDVPMILVGNKCDLEDERVVGKEQGQNLARQWNNCAFLESSAKSKINVNEIFYDLVRQINRKTPVPGKARKKSSCQLL", "length": 184 }, "evidence": [ { "id": "F1NSA8", "url": "https://omabrowser.org/oma/group/F1NSA8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P62833-1", "protein_name": "Ras-related protein Rap-1A", "gene_name": "RAP1A", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDCQQCMLEILDTAGTEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTEDVPMILVGNKCDLEDERVVGKEQGQNLARQWCNCAFLESSAKSKINVNEIFYDLVRQINRKTPVEKKKPKKKSCLLL", "length": 184 }, "evidence": [ { "id": "F1NSA8", "url": "https://omabrowser.org/oma/group/F1NSA8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P62834-1", "protein_name": "Ras-related protein Rap-1A", "gene_name": "RAP1A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDCQQCMLEILDTAGTEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTEDVPMILVGNKCDLEDERVVGKEQGQNLARQWCNCAFLESSAKSKINVNEIFYDLVRQINRKTPVEKKKPKKKSCLLL", "length": 184 }, "evidence": [ { "id": "F1NSA8", "url": "https://omabrowser.org/oma/group/F1NSA8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P62835-1", "protein_name": "Ras-related protein Rap-1A", "gene_name": "Rap1a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDCQQCMLEILDTAGTEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTEDVPMILVGNKCDLEDERVVGKEQGQNLARQWCNCAFLESSAKSKINVNEIFYDLVRQINRKTPVEKKKPKKKSCLLL", "length": 184 }, "evidence": [ { "id": "F1NSA8", "url": "https://omabrowser.org/oma/group/F1NSA8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P62836-1", "protein_name": "Ras-related protein Rap-1A", "gene_name": "Rap1a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDCQQCMLEILDTAGTEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTEDVPMILVGNKCDLEDERVVGKEQGQNLARQWCNCAFLESSAKSKINVNEIFYDLVRQINRKTPVEKKKPKKKSCLLL", "length": 184 }, "evidence": [ { "id": "F1NSA8", "url": "https://omabrowser.org/oma/group/F1NSA8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "Rap protein signal transduction", "id": "GO:0032486", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032486", "evidence": [ { "database": "UniProtKB", "id": "F1NSA8", "url": "https://www.uniprot.org/uniprotkb/F1NSA8" } ], "pmid": "" }, { "name": "negative regulation of synaptic vesicle exocytosis", "id": "GO:2000301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000301", "evidence": [ { "database": "UniProtKB", "id": "F1NSA8", "url": "https://www.uniprot.org/uniprotkb/F1NSA8" } ], "pmid": "" }, { "name": "cellular response to cAMP", "id": "GO:0071320", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071320", "evidence": [ { "database": "UniProtKB", "id": "F1NSA8", "url": "https://www.uniprot.org/uniprotkb/F1NSA8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "F1NSA8", "url": "https://www.uniprot.org/uniprotkb/F1NSA8" } ], "pmid": "" }, { "name": "G protein activity", "id": "GO:0003925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003925", "evidence": [ { "database": "UniProtKB", "id": "F1NSA8", "url": "https://www.uniprot.org/uniprotkb/F1NSA8" } ], "pmid": "" }, { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "F1NSA8", "url": "https://www.uniprot.org/uniprotkb/F1NSA8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "F1NSA8", "url": "https://www.uniprot.org/uniprotkb/F1NSA8" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1NSA8", "url": "https://www.uniprot.org/uniprotkb/F1NSA8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "19669", "name": "", "equation": "GTP + H2O = GDP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YVX9-1", "F1NSA8-1", "R4GJA4-1", "A0A1L1RKZ0-1", "E1BUS1-1", "Q5ZHW4-1", "Q90694-1", "P08070-1", "P09642-1", "P09643-1", "P09644-1", "P09645-1", "Q5F352-1", "Q5ZMS3-1", "Q90705-1", "Q90835-1", "Q90965-1", "Q98932-1", "A0A3Q2UHM4-1", "Q5ZHX1-1", "A0A1D5PT95-1", "E1BQI2-1", "F1NPF0-1", "A0A8V0XVU5-1", "A0A8V0XBX5-1", "A0A8V0Z564-1", "A0A8V0Y9R6-1", "A0A1D5PM27-1", "A0A8V0Z8U4-1", "A0A8V0ZJW2-1", "A0A8V1ABB1-1", "A0A8V0YDX6-1", "E1BWN3-1", "Q5F499-1", "Q5ZKU5-1", "P02552-1", "P08642-1", "P26990-1", "P42558-1", "Q5F470-1", "Q5ZIT5-1", "Q5ZJN2-1", "P50146-1", "A0A8V0ZNW3-1", "A0A8V0YIM0-1", "A0A8V0ZRZ2-1", "A0A8V1A9Z8-1", "Q1KME6-1", "Q5ZLG1-1", "P84172-1", "A0A8V1ACG4-1", "A0A8V0YTL7-1", "A0A3Q2UG55-1", "A0A8V1AIF5-1", "Q5ZHV1-1", "A0A8V0Z5P2-1", "A0A8V0Y4A4-1", "A0A8V0YA62-1", "A0A8V0YVM3-1", "A0A1D5P1F5-1", "A0A8V1ADZ7-1", "F1NWF1-1", "A0A8V1AP30-1", "A0A8V0XDD5-1", "A0A8V0XMC5-1", "A0A8V0YWW1-1", "A0A8V0ZR14-1", "A0A8V0Y2H3-1", "Q5ZJD3-1", "Q5ZM73-1", "Q5ZM83-1", "A0A8V0YTY9-1", "A0A8V0ZXW3-1", "A0A8V1AHB3-1", "A0A8V0YDI7-1", "A0A1D5NV13-1", "A0A8V0XGK7-1", "A0A8V0YHK2-1", "A0A8V0XC33-1", "A0A8V0XKC3-1", "F1P278-1", "A0A8V0ZG00-1", "A0A8V1AGP3-1", "A0A8V1AN75-1", "A0A8V0Z416-1", "A0A8V1A0V4-1", "A0A8V1A8Q7-1", "A0A8V1ABD3-1", "A0A8V1API8-1", "A0A8V0YIU8-1", "A0A8V0X962-1", "A0A8V1AKH3-1", "P79784-1", "A0A1D5P533-1", "A0A8V1A8I5-1", "A0A8V1AE09-1", "Q9PSX7-1", "Q5ZKR4-1", "A0A8V0YGN8-1", "A0A8V0XNL0-1", "A0A8V0Y3H2-1" ], "evidence": [ { "id": "19669", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/19669" } ] }, { "id": "R-GGA-169904", "name": "C3G stimulates nucleotide exchange on Rap1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1NSA8-1", "H9KZZ1-1" ], "evidence": [ { "id": "R-GGA-169904", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-169904" } ] }, { "id": "R-GGA-354060", "name": "Translocation of RIAM to plasma membrane", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q5ZHX1-1", "F1NSA8-1" ], "evidence": [ { "id": "R-GGA-354060", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-354060" } ] }, { "id": "R-GGA-354073", "name": "Autophosphorylation of PTK2 at Y397", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q5ZHX1-1", "F1NSA8-1", "A0A8V0ZDU6-1" ], "evidence": [ { "id": "R-GGA-354073", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-354073" } ] }, { "id": "R-GGA-354077", "name": "Integrin alphaIIb beta3 activation", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q5ZHX1-1", "A0A8V0ZND5-1", "F1NSA8-1", "A0A8V0ZDU6-1" ], "evidence": [ { "id": "R-GGA-354077", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-354077" } ] }, { "id": "R-GGA-354087", "name": "Recruitment of GRB2 to p-PTK2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q5ZHX1-1", "F1NSA8-1", "A0A8V0ZDU6-1" ], "evidence": [ { "id": "R-GGA-354087", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-354087" } ] }, { "id": "R-GGA-354097", "name": "Activation of Talin", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q5ZHX1-1", "F1NSA8-1" ], "evidence": [ { "id": "R-GGA-354097", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-354097" } ] }, { "id": "R-GGA-354124", "name": "Phosphorylation of pPTK2 by SRC", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q5ZHX1-1", "F1NSA8-1", "A0A8V0ZDU6-1" ], "evidence": [ { "id": "R-GGA-354124", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-354124" } ] }, { "id": "R-GGA-354149", "name": "Interaction of integrin alphaIIb beta3 with Fibrinogen", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q5ZHX1-1", "A0A8V0ZND5-1", "F1NSA8-1", "A0A8V0ZDU6-1" ], "evidence": [ { "id": "R-GGA-354149", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-354149" } ] }, { "id": "R-GGA-354165", "name": "Interaction of SOS with GRB2 bound to FADK1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q5ZHX1-1", "F1NSA8-1", "A0A8V0ZDU6-1" ], "evidence": [ { "id": "R-GGA-354165", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-354165" } ] }, { "id": "R-GGA-354173", "name": "Activation of Rap1 by cytosolic GEFs", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q5ZHX1-1", "F1NSA8-1" ], "evidence": [ { "id": "R-GGA-354173", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-354173" } ] }, { "id": "R-GGA-372693", "name": "Phosphorylation of BCAR1 by SRC-PTK2 complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q5ZHX1-1", "F1NSA8-1", "A0A8V0ZDU6-1" ], "evidence": [ { "id": "R-GGA-372693", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-372693" } ] }, { "id": "R-GGA-372697", "name": "Crk binding to p130cas", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q5ZHX1-1", "F1NSA8-1", "A0A8V0ZDU6-1" ], "evidence": [ { "id": "R-GGA-372697", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-372697" } ] }, { "id": "R-GGA-372705", "name": "Recruitment of BCAR1 to PTK2 complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q5ZHX1-1", "F1NSA8-1", "A0A8V0ZDU6-1" ], "evidence": [ { "id": "R-GGA-372705", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-372705" } ] }, { "id": "R-GGA-377640", "name": "Autophosphorylation of SRC", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q5ZHX1-1", "F1NSA8-1", "A0A8V0ZDU6-1" ], "evidence": [ { "id": "R-GGA-377640", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-377640" } ] }, { "id": "R-GGA-377641", "name": "Clustering of Integrin alphaIIb beta3 complexes", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q5ZHX1-1", "A0A8V0ZND5-1", "F1NSA8-1", "A0A8V0ZDU6-1" ], "evidence": [ { "id": "R-GGA-377641", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-377641" } ] }, { "id": "R-GGA-377643", "name": "Dephosphorylation of inactive SRC by PTPB1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q5ZHX1-1", "F1NSA8-1", "A0A8V0ZDU6-1", "A0A8V0YHN7-1" ], "evidence": [ { "id": "R-GGA-377643", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-377643" } ] }, { "id": "R-GGA-377644", "name": "Release of CSK from SRC", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q5ZHX1-1", "A0A8V0ZND5-1", "F1NSA8-1", "A0A8V0ZDU6-1" ], "evidence": [ { "id": "R-GGA-377644", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-377644" } ] }, { "id": "R-GGA-381727", "name": "RAP1A exchanges GDP for GTP", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1NSA8-1" ], "evidence": [ { "id": "R-GGA-381727", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-381727" } ] }, { "id": "R-GGA-392513", "name": "Rap1 signal termination by Rap1GAPs", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q5ZHX1-1", "F1NSA8-1" ], "evidence": [ { "id": "R-GGA-392513", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-392513" } ] }, { "id": "R-GGA-392835", "name": "Rap1 sequesters Raf1 to inhibit ERK cascade", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q5ZHX1-1", "F1NSA8-1", "P05625-1" ], "evidence": [ { "id": "R-GGA-392835", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-392835" } ] }, { "id": "R-GGA-429415", "name": "SYK binds to integrin alphaIIb beta3", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q5ZHX1-1", "F1NSA8-1", "A0A8V0ZDU6-1", "F1N9Y5-1" ], "evidence": [ { "id": "R-GGA-429415", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-429415" } ] }, { "id": "R-GGA-429441", "name": "SYK activation by SRC", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q5ZHX1-1", "F1NSA8-1", "A0A8V0ZDU6-1", "F1N9Y5-1" ], "evidence": [ { "id": "R-GGA-429441", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-429441" } ] }, { "id": "R-GGA-432096", "name": "Activated integrin alphaIIb beta3 binds SHC1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q5ZHX1-1", "A0A8V0ZND5-1", "F1NSA8-1", "A0A8V0ZDU6-1" ], "evidence": [ { "id": "R-GGA-432096", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-432096" } ] }, { "id": "R-GGA-443905", "name": "SHC1 bound to integrin alphaIIb beta3 is phosphorylated somehow", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q5ZHX1-1", "A0A8V0ZND5-1", "F1NSA8-1", "A0A8V0ZDU6-1" ], "evidence": [ { "id": "R-GGA-443905", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-443905" } ] }, { "id": "R-GGA-443910", "name": "SHC1 dissociates from integrin alphaIIb beta3", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q5ZHX1-1", "A0A8V0ZND5-1", "F1NSA8-1", "A0A8V0ZDU6-1" ], "evidence": [ { "id": "R-GGA-443910", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-443910" } ] }, { "id": "R-GGA-5672973", "name": "MAP2Ks phosphorylate MAPKs", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P53478-1", "Q5F352-1", "A0A1D5PX90-1", "Q5ZHX1-1", "A0A8V1AP60-1", "A0A8V0ZND5-1", "F1NSA8-1", "A0A8V1A4Q4-1", "A0A8V0ZDU6-1", "P05625-1", "P08642-1", "Q5ZMQ2-1", "A0A8V0YLV1-1", "A0A8V0YMN5-1" ], "evidence": [ { "id": "R-GGA-5672973", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5672973" } ] }, { "id": "R-GGA-5672978", "name": "RAF phosphorylates MAP2K dimer", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P53478-1", "Q5F352-1", "A0A1D5PX90-1", "Q5ZHX1-1", "A0A8V1AP60-1", "A0A8V0ZND5-1", "F1NSA8-1", "A0A8V1A4Q4-1", "A0A8V0ZDU6-1", "P05625-1", "P08642-1", "Q5ZMQ2-1", "A0A8V0YLV1-1", "A0A8V0YMN5-1" ], "evidence": [ { "id": "R-GGA-5672978", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5672978" } ] }, { "id": "R-GGA-6799350", "name": "Exocytosis of specific granule membrane proteins", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane, specific granule membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XBX5-1", "A0A3Q2U2N5-1", "A0A8V1AKE3-1", "P15120-1", "A0A1D5P3W4-1", "Q5F3C1-1", "A0A8V1AN75-1", "A0A8V0ZZE4-1", "F1NSA8-1", "A0A8V0YXK7-1", "A0A8V0Y5N7-1", "A0A8V0YIN5-1", "A0A8V0YJI3-1", "A0A8V0YMC7-1" ], "evidence": [ { "id": "R-GGA-6799350", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6799350" } ] }, { "id": "R-GGA-8875568", "name": "RAPGEF1 activates RAP1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0M8T9-1", "Q5ZHX1-1", "F1NSA8-1" ], "evidence": [ { "id": "R-GGA-8875568", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8875568" } ] }, { "id": "R-GGA-939265", "name": "Activation of Rap1 by membrane-associated GEFs", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q5ZHX1-1", "F1NSA8-1" ], "evidence": [ { "id": "R-GGA-939265", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-939265" } ] }, { "id": "R-GGA-9610163", "name": "BRAF autophosphorylates downstream of RAP1 and NGF", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "endosome membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1NSA8-1", "A0A8V0YMN5-1" ], "evidence": [ { "id": "R-GGA-9610163", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9610163" } ] }, { "id": "R-GGA-9657599", "name": "Dual mechanism MAP2K inhibitors bind MAP2Ks", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P53478-1", "Q5F352-1", "A0A1D5PX90-1", "Q5ZHX1-1", "A0A8V1AP60-1", "A0A8V0ZND5-1", "F1NSA8-1", "A0A8V1A4Q4-1", "A0A8V0ZDU6-1", "P05625-1", "P08642-1", "Q5ZMQ2-1", "A0A8V0YLV1-1", "A0A8V0YMN5-1" ], "evidence": [ { "id": "R-GGA-9657599", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9657599" } ] }, { "id": "R-GGA-9657603", "name": "Dual mechanism MAPK inhibitors bind MAPKs", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P53478-1", "Q5F352-1", "A0A1D5PX90-1", "Q5ZHX1-1", "A0A8V1AP60-1", "A0A8V0ZND5-1", "F1NSA8-1", "A0A8V1A4Q4-1", "A0A8V0ZDU6-1", "P05625-1", "P08642-1", "Q5ZMQ2-1", "A0A8V0YLV1-1", "A0A8V0YMN5-1" ], "evidence": [ { "id": "R-GGA-9657603", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9657603" } ] }, { "id": "R-GGA-9657606", "name": "Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P53478-1", "Q5F352-1", "A0A1D5PX90-1", "Q5ZHX1-1", "A0A8V1AP60-1", "A0A8V0ZND5-1", "F1NSA8-1", "A0A8V1A4Q4-1", "A0A8V0ZDU6-1", "P05625-1", "P08642-1", "Q5ZMQ2-1", "A0A8V0YLV1-1", "A0A8V0YMN5-1" ], "evidence": [ { "id": "R-GGA-9657606", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9657606" } ] }, { "id": "R-GGA-9657608", "name": "Single mechanism MAPK inhibitors bind phosphorylated MAPK", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P53478-1", "Q5F352-1", "A0A1D5PX90-1", "Q5ZHX1-1", "A0A8V1AP60-1", "A0A8V0ZND5-1", "F1NSA8-1", "A0A8V1A4Q4-1", "A0A8V0ZDU6-1", "P05625-1", "P08642-1", "Q5ZMQ2-1", "A0A8V0YLV1-1", "A0A8V0YMN5-1" ], "evidence": [ { "id": "R-GGA-9657608", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9657608" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5NV13", "gene_name": "RIT2", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5NV13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NV13" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A1D5NV13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NV13" } ] } ] }, { "uniprot_ac": "A0A1D5P1F5", "gene_name": "RAB40C", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5P1F5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1F5" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A1D5P1F5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1F5" } ] } ] }, { "uniprot_ac": "A0A1D5P3W4", "gene_name": "SLC27A2", "activity": [ { "ec_number": "6.2.1.3", "activity": "a long-chain fatty acid + ATP + CoA = a long-chain fatty acyl-CoA + AMP + diphosphate.", "evidence": [ { "id": "A0A1D5P3W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P3W4" } ] }, { "ec_number": "6.2.1.3", "activity": "", "evidence": [ { "id": "A0A1D5P3W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P3W4" } ] } ] }, { "uniprot_ac": "A0A1D5P533", "gene_name": "RASEF", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5P533", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P533" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A1D5P533", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P533" } ] } ] }, { "uniprot_ac": "A0A1D5PM27", "gene_name": "OPA1", "activity": [ { "ec_number": "3.6.5.5", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5PM27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PM27" } ] }, { "ec_number": "3.6.5.5", "activity": "", "evidence": [ { "id": "A0A1D5PM27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PM27" } ] } ] }, { "uniprot_ac": "A0A1D5PT95", "gene_name": "KRAS", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", 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H(+).", "evidence": [ { "id": "A0A8V0XDD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XDD5" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0XDD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XDD5" } ] } ] }, { "uniprot_ac": "A0A8V0XGK7", "gene_name": "RAB6A", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XGK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XGK7" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0XGK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XGK7" } ] } ] }, { "uniprot_ac": "A0A8V0XKC3", "gene_name": "RAB18", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XKC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XKC3" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0XKC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XKC3" } ] } ] }, { "uniprot_ac": "A0A8V0XMC5", "gene_name": "RAB10L", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XMC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMC5" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0XMC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMC5" } ] } ] }, { "uniprot_ac": "A0A8V0XNL0", "gene_name": "RABL2A", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XNL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNL0" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0XNL0", "database": "UniProtKB", "url": 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"ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0YVX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVX9" } ] } ] }, { "uniprot_ac": "A0A8V0YWW1", "gene_name": "RAB33A", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YWW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YWW1" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0YWW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YWW1" } ] } ] }, { "uniprot_ac": "A0A8V0YXK7", "gene_name": "HMOX2", "activity": [ { "ec_number": "1.14.14.18", "activity": "heme b + 3 reduced [NADPH--hemoprotein reductase] + 3 O2 = biliverdin IXalpha + CO + Fe(2+) + 3 oxidized [NADPH--hemoprotein reductase] + 3 H2O + H(+).", "evidence": [ { "id": "A0A8V0YXK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXK7" } ] }, { "ec_number": 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"database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJW2" } ] } ] }, { "uniprot_ac": "A0A8V0ZND5", "gene_name": "CSK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZND5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZND5" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0ZND5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZND5" } ] } ] }, { "uniprot_ac": "A0A8V0ZNW3", "gene_name": "ENTPD1", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "A0A8V0ZNW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNW3" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "A0A8V0ZNW3", "database": 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"activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZXW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXW3" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0ZXW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXW3" } ] } ] }, { "uniprot_ac": "A0A8V0ZZE4", "gene_name": "OBSCN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZZE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZE4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZZE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZE4" } ] } ] }, { "uniprot_ac": "A0A8V1A0V4", "gene_name": "RAB18L", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", 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"database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9Z8" } ] } ] }, { "uniprot_ac": "A0A8V1ABB1", "gene_name": "", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1ABB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABB1" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V1ABB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABB1" } ] } ] }, { "uniprot_ac": "A0A8V1ABD3", "gene_name": "RAB36", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1ABD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABD3" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V1ABD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABD3" } ] } ] }, { "uniprot_ac": "A0A8V1ACG4", "gene_name": 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"id": "NP_001026601", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026601" } ] } ], "protein_names": [ { "name": "Tyrosine-protein kinase SYK", "type": "recommended", "evidence": [ { "id": "F1N9Y5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N9Y5/entry#names_and_taxonomy" } ] }, { "name": "2.7.10.2", "type": "synonym", "evidence": [ { "id": "F1N9Y5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N9Y5/entry#names_and_taxonomy" } ] }, { "name": "spleen tyrosine kinase", "type": "synonym", "evidence": [ { "id": "NP_001026601", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026601" } ] }, { "name": "tyrosine-protein kinase SYK", "type": "synonym", "evidence": [ { "id": "NP_001026601", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026601" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ720543.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000094.1. On Sep 23, 2021 this sequence version replaced NP_001026601.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.", "evidence": [ { "database": "RefSeq", "id": "NP_001026601", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026601" } ] }, { "annotation": "Analysis of controlled B cell receptor triggering ex vivo and on primary murine B cells reveals that Src family kinases are required for signal initiation and Syk activation.", "evidence": [ { "database": "RefSeq", "id": "NP_001026601", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026601" }, { "database": "PubMed", "id": "23335753", "url": "https://glygen.org/publication/PubMed/23335753" } ] }, { "annotation": "In hydrogen peroxide-stimulated DT40 cells, BLNK is phosphorylated by Syk and not by Btk.", "evidence": [ { "database": "RefSeq", "id": "NP_001026601", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026601" }, { "database": "PubMed", "id": "11434777", "url": "https://glygen.org/publication/PubMed/11434777" } ] }, { "annotation": "Non-receptor tyrosine kinase which mediates signal transduction downstream of a variety of transmembrane receptors including classical immunoreceptors like the B-cell receptor (BCR). Regulates several biological processes including innate and adaptive immunity, cell adhesion, osteoclast maturation, platelet activation and vascular development. Assembles into signaling complexes with activated receptors at the plasma membrane via interaction between its SH2 domains and the receptor tyrosine-phosphorylated ITAM domains. The association with the receptor can also be indirect and mediated by adapter proteins containing ITAM or partial hemITAM domains. The phosphorylation of the ITAM domains is generally mediated by SRC subfamily kinases upon engagement of the receptor. More rarely signal transduction via SYK could be ITAM-independent. Direct downstream effectors phosphorylated by SYK include DEPTOR, VAV1, PLCG1, PI-3-kinase, LCP2 and BLNK. Initially identified as essential in B-cell receptor (BCR) signaling, it is necessary for the maturation of B-cells most probably at the pro-B to pre-B transition. Activated upon BCR engagement, it phosphorylates and activates BLNK an adapter linking the activated BCR to downstream signaling adapters and effectors.", "evidence": [ { "database": "UniProtKB", "id": "F1N9Y5", "url": "https://www.uniprot.org/uniprotkb/F1N9Y5#function" }, { "database": "PubMed", "id": "9697839", "url": "https://glygen.org/publication/PubMed/9697839" } ] }, { "annotation": "Results suggest that the uncommon recognition determinant of two closely spaced tyrosines is a limiting factor in NFAT signaling via Syk association with Vav1.", "evidence": [ { "database": "RefSeq", "id": "NP_001026601", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026601" }, { "database": "PubMed", "id": "21606197", "url": "https://glygen.org/publication/PubMed/21606197" } ] }, { "annotation": "Syk tyrosine kinase has a role in signaling dynamics of the B cell antigen receptor", "evidence": [ { "database": "RefSeq", "id": "NP_001026601", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026601" }, { "database": "PubMed", "id": "17913708", "url": "https://glygen.org/publication/PubMed/17913708" } ] }, { "annotation": "The Dok-3/Grb2 protein signal module attenuates Lyn kinase-dependent activation of Syk kinase in B cell antigen receptor microclusters", "evidence": [ { "database": "RefSeq", "id": "NP_001026601", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026601" }, { "database": "PubMed", "id": "23223229", "url": "https://glygen.org/publication/PubMed/23223229" } ] }, { "annotation": "The simultaneous but not the independent suppression of Lyn and Syk expression prevents the activation of Ca2+-release activated Ca2+ current without interfering with thapsigargin-sensitive Ca(2+) store release in DT40 B lymphocyte cells.", "evidence": [ { "database": "RefSeq", "id": "NP_001026601", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026601" }, { "database": "PubMed", "id": "17452533", "url": 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"database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-354192", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-354192", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5621480", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5621480", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-912631", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-912631", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9705462", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9705462", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-983695", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001026601", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026601", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "10596", "url": "https://www.rhea-db.org/rhea/10596", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A0A0MQ53", "url": "https://www.uniprot.org/uniprotkb/A0A0A0MQ53", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A0A0MQ53-1", "url": "https://www.uniprot.org/uniprotkb/A0A0A0MQ53-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y1F7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y1F7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y1F7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y1F7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y9Z4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9Z4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y9Z4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9Z4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N9Y5", "url": "https://www.uniprot.org/uniprotkb/F1N9Y5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N9Y5-1", "url": "https://www.uniprot.org/uniprotkb/F1N9Y5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASNMANPANHLPYFFGNITREEAEEYLMQGGMSDGLYLLRQSRNYLGGFALSLAYGRKVHHYTIERELSGTYAIAGGKSHASPAELINYHSEEADGLICLLRKSFNRPPGVEPKTGPFEDLKENLIREYVKQTWNLQGHALEQAIISQKPQLEKLIATTAHEKMPWFHGRISREESEHRILIGSRNNGKFLIRERDSNGSYALCLLNDGKVLHYRIDRDKTGKLSIPDGKRFDTLWQLVEHYSYKPDGLLRVLSIPCPRHGSESDNVVFDTRPLPGTPSKLQTPIGAPSDDQTPFNPYVLQRARGLIGAEKGDQREALPMDTEVYESPYADPDEIKPKNVTLDRKLLTLEEGELGSGNFGTVKKGFYKMKKGAKPVAVKILKNESNDPAIKDELLREANVMQQLDNPYIVRMIGICEAEAWMLVMEMAELGPLNKFLQKNRHVTEKNITELVHQVSMGMKYLEENNFVHRDLAARNVLLVTQHYAKISDFGLSKALSADENYYKAQSHGKWPVKWYAPECMNFYKFSSKSDVWSFGVLMWEAFSYGQKPYKGMKGGEVAQMIERGERMECPEACPVEVYDLMKLCWTYNVDDRPGFVAVELRLRNYYYDISH", "length": 613, "header": "sp|F1N9Y5-1|KSYK_CHICK Isoform 1 of Tyrosine-protein kinase SYK OS=Gallus gallus OX=9031 GN=SYK PE=1 SV=2 CANONICAL=F1N9Y5-1" }, "isoforms": [ { "isoform_ac": "A0A0A0MQ53-1", "url": "https://www.uniprot.org/uniprotkb/F1N9Y5/entry#A0A0A0MQ53-1", "sequence": { "sequence": "MASNMANPANHLPYFFGNITREEAEEYLMQGGMSDGLYLLRQSRNYLGGFALSLAYGRKVHHYTIERELSGTYAIAGGKSHASPAELINYHSEEADGLICLLRKSFNRPPGVEPKTGPFEDLKENLIREYVKQTWNLQGHALEQAIISQKPQLEKLIATTAHEKMPWFHGRISREESEHRILIGSRNNGKFLIRERDSNGSYALCLLNDGKVLHYRIDRDKTGKLSIPDGKRFDTLWQLVEHYSYKPDGLLRVLSIPCPRHGSESDNVVFDTRPLPGTPSKSWARGGIISRLKSYTFPKAGSKKLQTPIGAPSDDQTPFNPYVLQRARGLIGAEKGDQREALPMDTEVYESPYADPDEIKPKNVTLDRKLLTLEEGELGSGNFGTVKKGFYKMKKGAKPVAVKILKNESNDPAIKDELLREANVMQQLDNPYIVRMIGICEAEAWMLVMEMAELGPLNKFLQKNRHVTEKNITELVHQVSMGMKYLEENNFVHRDLAARNVLLVTQHYAKISDFGLSKALSADENYYKAQSHGKWPVKWYAPECMNFYKFSSKSDVWSFGVLMWEAFSYGQKPYKGMKGGEVAQMIERGERMECPEACPVEVYDLMKLCWTYNVDDRPGFVAVELRLRNYYYDISH", "length": 636, "header": "tr|A0A0A0MQ53-1|KSYK_CHICK Computationally mapped isoform of Tyrosine-protein kinase SYK OS=Gallus gallus OX=9031 GN=SYK PE=1 SV=1 CANONICAL=F1N9Y5-1" }, "locus": { "chromosome": "Z", "start_pos": 44709818, "end_pos": 44676799, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010022258.1", "url": "https://www.ensembl.org/id/ENSGALT00010022258.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010012791.1", "url": "https://www.ensembl.org/id/ENSGALP00010012791.1" } ] } }, { "isoform_ac": "A0A8V0Y1F7-1", "url": "https://www.uniprot.org/uniprotkb/F1N9Y5/entry#A0A8V0Y1F7-1", "sequence": { "sequence": "MASNMANPANHLPYFFGNITREEAEEYLMQGGMSDGLYLLRQSRNYLGGFALSLAYGRKVHHYTIERELSGTYAIAGGKSHASPAELINYHSEEADGLICLLRKSFNRPPGVEPKTGPFEDLKENLIREYVKQTWNLQGHALEQAIISQKPQLEKLIATTAHEKMPWFHGRISREESEHRILIGSRNNGKFLIRERDSNGSYALCLLNDGKVLHYRIDRDKTGKLSIPDGKRFDTLWQLVEHYSYKPDGLLRVLSIPCPRHGSESDNVVFDTRPLPGTPSKSWARGGIISRLKSYTFPKAGSKKEMAFSTLFHRRNELQTPIGAPSDDQTPFNPYVLQRARGLIGAEKGDQREALPMDTEVYESPYADPDEIKPKNVTLDRKLLTLEEGELGSGNFGTVKKGFYKMKKGAKPVAVKILKNESNDPAIKDELLREANVMQQLDNPYIVRMIGICEAEAWMLVMEMAELGPLNKFLQKNRHVTEKNITELVHQVSMGMKYLEENNFVHRDLAARNVLLVTQHYAKISDFGLSKALSADENYYKAQSHGKWPVKWYAPECMNFYKFSSKSDVWSFGVLMWEAFSYGQKPYKGMKGGEVAQMIERGERMECPEACPVEVYDLMKLCWTYNVDDRPGFVAVELRLRNYYYDISH", "length": 649, "header": "tr|A0A8V0Y1F7-1|A0A8V0Y1F7_CHICK Computationally mapped isoform of Tyrosine-protein kinase SYK OS=Gallus gallus OX=9031 GN=SYK PE=1 SV=1 CANONICAL=F1N9Y5-1" }, "locus": { "chromosome": "Z", "start_pos": 44709818, "end_pos": 44676799, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010022256.1", "url": "https://www.ensembl.org/id/ENSGALT00010022256.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010012788.1", "url": "https://www.ensembl.org/id/ENSGALP00010012788.1" } ] } }, { "isoform_ac": "A0A8V0Y9Z4-1", "url": "https://www.uniprot.org/uniprotkb/F1N9Y5/entry#A0A8V0Y9Z4-1", "sequence": { "sequence": "MASNMANPANHLPYFFGNITREEAEEYLMQGGMSDGLYLLRQSRNYLGGFALSLAYGRKVHHYTIERELSGTYAIAGGKSHASPAELINYHSEEADGLICLLRKSFNRPPGVEPKTGPFEDLKENLIREYVKQTWNLQGHALEQAIISQKPQLEKLIATTAHEKMPWFHGRISREESEHRILIGSRNNGKFLIRERDSNGSYALCLLNDGKVLHYRIDRDKTGKLSIPDGKRFDTLWQLVEHYSYKPDGLLRVLSIPCPRHGSESDNVVFDTRPLPGTPSKEMAFSTLFHRRNELQTPIGAPSDDQTPFNPYVLQRARGLIGAEKGDQREALPMDTEVYESPYADPDEIKPKNVTLDRKLLTLEEGELGSGNFGTVKKGFYKMKKGAKPVAVKILKNESNDPAIKDELLREANVMQQLDNPYIVRMIGICEAEAWMLVMEMAELGPLNKFLQKNRHVTEKNITELVHQVSMGMKYLEENNFVHRDLAARNVLLVTQHYAKISDFGLSKALSADENYYKAQSHGKWPVKWYAPECMNFYKFSSKSDVWSFGVLMWEAFSYGQKPYKGMKGGEVAQMIERGERMECPEACPVEVYDLMKLCWTYNVDDRPGFVAVELRLRNYYYDISH", "length": 626, "header": "tr|A0A8V0Y9Z4-1|A0A8V0Y9Z4_CHICK Computationally mapped isoform of Tyrosine-protein kinase OS=Gallus gallus OX=9031 GN=SYK PE=1 SV=1 CANONICAL=F1N9Y5-1" }, "locus": { "chromosome": "Z", "start_pos": 44709818, "end_pos": 44676799, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010022262.1", "url": "https://www.ensembl.org/id/ENSGALT00010022262.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010012795.1", "url": "https://www.ensembl.org/id/ENSGALP00010012795.1" } ] } }, { "isoform_ac": "F1N9Y5-1", "url": "https://www.uniprot.org/uniprotkb/F1N9Y5/entry#F1N9Y5-1", "sequence": { "sequence": "MASNMANPANHLPYFFGNITREEAEEYLMQGGMSDGLYLLRQSRNYLGGFALSLAYGRKVHHYTIERELSGTYAIAGGKSHASPAELINYHSEEADGLICLLRKSFNRPPGVEPKTGPFEDLKENLIREYVKQTWNLQGHALEQAIISQKPQLEKLIATTAHEKMPWFHGRISREESEHRILIGSRNNGKFLIRERDSNGSYALCLLNDGKVLHYRIDRDKTGKLSIPDGKRFDTLWQLVEHYSYKPDGLLRVLSIPCPRHGSESDNVVFDTRPLPGTPSKLQTPIGAPSDDQTPFNPYVLQRARGLIGAEKGDQREALPMDTEVYESPYADPDEIKPKNVTLDRKLLTLEEGELGSGNFGTVKKGFYKMKKGAKPVAVKILKNESNDPAIKDELLREANVMQQLDNPYIVRMIGICEAEAWMLVMEMAELGPLNKFLQKNRHVTEKNITELVHQVSMGMKYLEENNFVHRDLAARNVLLVTQHYAKISDFGLSKALSADENYYKAQSHGKWPVKWYAPECMNFYKFSSKSDVWSFGVLMWEAFSYGQKPYKGMKGGEVAQMIERGERMECPEACPVEVYDLMKLCWTYNVDDRPGFVAVELRLRNYYYDISH", "length": 613, "header": "sp|F1N9Y5-1|KSYK_CHICK Isoform 1 of Tyrosine-protein kinase SYK OS=Gallus gallus OX=9031 GN=SYK PE=1 SV=2 CANONICAL=F1N9Y5-1" }, "locus": { "chromosome": "Z", "start_pos": 44709818, "end_pos": 44676799, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010022248.1", "url": "https://www.ensembl.org/id/ENSGALT00010022248.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010012784.1", "url": "https://www.ensembl.org/id/ENSGALP00010012784.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 278, "start_aa": "Thr", "end_pos": 278, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr278", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "Bruton's tyrosine kinase is essential for hydrogen peroxide-induced calcium signaling.", "journal": "Biochemistry", "date": "2001-07-10", "authors": "Qin S, Chock P B", "evidence": [ { "database": "RefSeq", "id": "NP_001026601", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026601" } ], "reference": [ { "type": "PubMed", "id": "11434777", "url": "https://glygen.org/publication/PubMed/11434777" } ] }, { "title": "Sequence and comparative analysis of the chicken genome provide unique perspectives on vertebrate evolution.", "journal": "Nature", "date": "2004", "authors": "", "evidence": [ { "database": "UniProtKB", "id": "F1N9Y5", "url": "https://www.uniprot.org/uniprotkb/F1N9Y5" } ], "reference": [ { "type": "PubMed", "id": "15592404", "url": "https://glygen.org/publication/PubMed/15592404" } ] }, { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "F1N9Y5", "url": "https://www.uniprot.org/uniprotkb/F1N9Y5" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] }, { "title": "Coupling Ca2+ store release to Icrac channel activation in B lymphocytes requires the activity of Lyn and Syk kinases.", "journal": "The Journal of cell biology", "date": "2007-04-23", "authors": "Chung S Clare, Limnander Andre, Kurosaki Tomohiro, Weiss Arthur, Korenbrot Juan I", "evidence": [ { "database": "RefSeq", "id": "NP_001026601", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026601" } ], "reference": [ { "type": "PubMed", "id": "17452533", "url": "https://glygen.org/publication/PubMed/17452533" } ] }, { "title": "Generation of an analog-sensitive Syk tyrosine kinase for the study of signaling dynamics from the B cell antigen receptor.", "journal": "The Journal of biological chemistry", "date": "2007-11-16", "authors": "Oh Hyunju, Ozkirimli Elif, Shah Kavita, Harrison Marietta L, Geahlen Robert L", "evidence": [ { "database": "RefSeq", "id": "NP_001026601", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026601" } ], "reference": [ { "type": "PubMed", "id": "17913708", "url": "https://glygen.org/publication/PubMed/17913708" } ] }, { "title": "Two closely spaced tyrosines regulate NFAT signaling in B cells via Syk association with Vav.", "journal": "Molecular and cellular biology", "date": "2011", "authors": "Chen CH, Martin VA, Gorenstein NM, Geahlen RL, Post CB", "evidence": [ { "database": "RefSeq", "id": "NP_001026601", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026601" } ], "reference": [ { "type": "PubMed", "id": "21606197", "url": "https://glygen.org/publication/PubMed/21606197" } ] }, { "title": "The Dok-3/Grb2 protein signal module attenuates Lyn kinase-dependent activation of Syk kinase in B cell antigen receptor microclusters.", "journal": "The Journal of biological chemistry", "date": "2013", "authors": "Losing M, Goldbeck I, Manno B, Oellerich T, Schnyder T, Bohnenberger H, Stork B, Urlaub H, Batista FD, Wienands J, Engelke M", "evidence": [ { "database": "RefSeq", "id": "NP_001026601", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026601" } ], "reference": [ { "type": "PubMed", "id": "23223229", "url": "https://glygen.org/publication/PubMed/23223229" } ] }, { "title": "Nonredundant roles of Src-family kinases and Syk in the initiation of B-cell antigen receptor signaling.", "journal": "Journal of immunology (Baltimore, Md. : 1950)", "date": "2013-02-15", "authors": "Stepanek Ondrej, Draber Peter, Drobek Ales, Horejsi Vaclav, Brdicka Tomas", "evidence": [ { "database": "RefSeq", "id": "NP_001026601", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026601" } ], "reference": [ { "type": "PubMed", "id": "23335753", "url": "https://glygen.org/publication/PubMed/23335753" } ] }, { "title": "BLNK: a central linker protein in B cell activation.", "journal": "Immunity", "date": "1998", "authors": "Fu C, Turck CW, Kurosaki T, Chan AC", "evidence": [ { "database": "UniProtKB", "id": "F1N9Y5", "url": "https://www.uniprot.org/uniprotkb/F1N9Y5" } ], "reference": [ { "type": "PubMed", "id": "9697839", "url": "https://glygen.org/publication/PubMed/9697839" } ] } ], "pathway": [ { "id": "gga:427272", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427272", "resource": "KEGG Pathway" }, { "id": "R-GGA-114604", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-114604", "resource": "Reactome", "description": "GPVI-mediated activation cascade" }, { "id": "R-GGA-2029482", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2029482", "resource": "Reactome", "description": "Regulation of actin dynamics for phagocytic cup formation" }, { "id": "R-GGA-2029485", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2029485", "resource": "Reactome", "description": "Role of 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"https://www.reactome.org/PathwayBrowser/#R-GGA-5621480", "resource": "Reactome", "description": "Dectin-2 family" }, { "id": "R-GGA-912631", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-912631", "resource": "Reactome", "description": "Regulation of signaling by CBL" }, { "id": "R-GGA-9705462", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9705462", "resource": "Reactome", "description": "Inactivation of CSF3 (G-CSF) signaling" }, { "id": "R-GGA-983695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983695", "resource": "Reactome", "description": "Antigen activates B Cell Receptor (BCR) leading to generation of second messengers" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1MHG9-1", "protein_name": "Tyrosine-protein kinase", "gene_name": "SYK", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGDGANNLPFFFGNITREEAEDYLVQGGMSDGLYLLRQSRNYLGGFALSVAHDRKAHHYTIERELNGTYAITGGRAHGSPAELCHYHTQELDGLVCLLKKPFNRPPGVQPKTGPFEDLKENLIREYVKQTWNLQGQALEQAIISQKPQLEKLIATTAHEKMPWFHGKISRDESEQIVLIGSKTNGKFLIRAKDNGSYALCLLHEGKVLHYRIDKDKTGKLSIPGGKNFDTLWQLVEHYSYKSDGLLRVLTVPCQKIGGQSGNINFRPQLPSSHPGTWSAGGIISRIKSYSFPKRDHRKTRTSSGNQVDSSTTFNPYEPDRGPWANEREAQREALPMDTEVYESPYADPEEIRPKEVYLDRKLLTLEDKELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLAEANVMQQLDNPYIVRMIGICEAESWMLVMEMAELGPLNKYLQQNRHVKDKNIIELVHQVSMGMKYLEECNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVSAMLEKGERMGCPPGCPREMYELMTLCWTYDVENRPGFVAVELRLRNYYYDVVN", "length": 628 }, "evidence": [ { "id": "F1N9Y5", "url": "https://omabrowser.org/oma/group/F1N9Y5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A4X1SFQ0-1", "protein_name": "Tyrosine-protein kinase", "gene_name": "SYK", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MADSANHLPFFFGNITREEAEDYLVQGGMSDGLYLLRQSRNYLGGFALSVAYDRKAHHYTIERELNGTYAISGGRTHGSPAELCHYHSQELDGLVCLLKNPFNRPPGVQPKTGPFEDLKENLIREYVKQTWNLQGQALEQAIISQKPQLEKLIATTAHEKMPWFHGKISRDESEQIVLIGSKTNGKFLIRARDNGSYALCLLHEGKVLHYRIDKDKTGKLSIPGGKNFDTLWQLVEHYSYKSDGLLRVLTVPCQKIGGQTGNDSFRPQLPSAHPATWSAGGIISRIKSYSFPKPGHRKASSPQGNRPESLVSYNPYESDRGPWANEREAQREALPMDTEVYESPYADPEEIRPKEVYLDRKLLTLEDKELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLAEANVMQQLDNPYIVRMIGICEAESWMLVMEMAELGPLNKYLQQNRHVKDKNIIELVHQVSMGMKYLEECNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVSAMLEKGERMGCPPGCPREMYELMTLCWTYDVENRPGFVAVELRLRNYYYDVVN", "length": 628 }, "evidence": [ { "id": "F1N9Y5", "url": "https://omabrowser.org/oma/group/F1N9Y5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8M2B201-1", "protein_name": "Tyrosine-protein kinase", "gene_name": "syk", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MVDKVHLLPYFFGNITREESEVYLQQGGSGDGLYLLRQSRSFLGGYALSLSYGRQFYHYTIERELNDTYAIAGGKSHRTPIDVINYHSQESDGLICLLKKPFHRPRGTEPKVGPFEDLKEQLIRQYVEQTWNLKGSALDQAIISQRPQLEKLIATTAHEKMPWFHGKIDREDSELRLLNTSRVNGKFLIRQRENSGRNESYALCLLHNNQVMHYRIDKDRAGKLSIPDGKKFDTLWQLVEHYSYKPDGLLRVLTETCPRPSHHSERGATGGIISRLKSYSFPKPGQKKGSAENPYKITPNGKDDYSKQGNFLDSAMPMDTQVYESPYADPDELRSTKVNRSDLTLEDGELGSGNFGTVLRGVYQMKKTQKVVAVKILKNDDDNAAVKDEMLREANVMQQLDNPYIVRMIGICEAENLMLVMELAELGPLHKFLQKNKHITVKNLTELVHQVSMGMKYLEEHNFVHRDLAARNVLLVTQHYAKISDFGLSKALTEDENYYKAKGHGKWPLKWYAPECMNYLKFSSKSDVWSFGVLMWEAFSYGQKPYKGMKGNEVIQMIENGQRMSAPPDCPPEMYDLMKKCWTYKPDERPGFSVVEPRLRHYYYDISQ", "length": 608 }, "evidence": [ { "id": "F1N9Y5", "url": "https://omabrowser.org/oma/group/F1N9Y5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "P43405-1", "protein_name": "Tyrosine-protein kinase SYK", "gene_name": "SYK", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASSGMADSANHLPFFFGNITREEAEDYLVQGGMSDGLYLLRQSRNYLGGFALSVAHGRKAHHYTIERELNGTYAIAGGRTHASPADLCHYHSQESDGLVCLLKKPFNRPQGVQPKTGPFEDLKENLIREYVKQTWNLQGQALEQAIISQKPQLEKLIATTAHEKMPWFHGKISREESEQIVLIGSKTNGKFLIRARDNNGSYALCLLHEGKVLHYRIDKDKTGKLSIPEGKKFDTLWQLVEHYSYKADGLLRVLTVPCQKIGTQGNVNFGGRPQLPGSHPATWSAGGIISRIKSYSFPKPGHRKSSPAQGNRQESTVSFNPYEPELAPWAADKGPQREALPMDTEVYESPYADPEEIRPKEVYLDRKLLTLEDKELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLAEANVMQQLDNPYIVRMIGICEAESWMLVMEMAELGPLNKYLQQNRHVKDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGERMGCPAGCPREMYDLMNLCWTYDVENRPGFAAVELRLRNYYYDVVN", "length": 635 }, "evidence": [ { "id": "F1N9Y5", "url": "https://omabrowser.org/oma/group/F1N9Y5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P48025-1", "protein_name": "Tyrosine-protein kinase SYK", "gene_name": "Syk", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAGSAVDSANHLTYFFGNITREEAEDYLVQGGMTDGLYLLRQSRNYLGGFALSVAHNRKAHHYTIERELNGTYAISGGRAHASPADLCHYHSQEPDGLICLLKKPFNRPPGVQPKTGPFEDLKENLIREYVKQTWNLQGQALEQAIISQKPQLEKLIATTAHEKMPWFHGNISRDESEQTVLIGSKTNGKFLIRARDNSGSYALCLLHEGKVLHYRIDRDKTGKLSIPEGKKFDTLWQLVEHYSYKPDGLLRVLTVPCQKIGAQMGHPGSPNAHPVTWSPGGIISRIKSYSFPKPGHKKPAPPQGSRPESTVSFNPYEPTGGPWGPDRGLQREALPMDTEVYESPYADPEEIRPKEVYLDRSLLTLEDNELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLAEANVMQQLDNPYIVRMIGICEAESWMLVMEMAELGPLNKYLQQNRHIKDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGERMGCPAGCPREMYDLMNLCWTYDVENRPGFTAVELRLRNYYYDVVN", "length": 629 }, "evidence": [ { "id": "F1N9Y5", "url": "https://omabrowser.org/oma/group/F1N9Y5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q64725-1", "protein_name": "Tyrosine-protein kinase SYK", "gene_name": "Syk", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGNAVDNANHLTYFFGNITREEAEDYLVQGGMTDGLYLLRQSRNYLGGFALSVAHNRKAHHYTIERELNGTYAISGGRAHASPADLCHYHSQEPEGLVCLLKKPFNRPPGVQPKTGPFEDLKENLIREYVKQTWNLQGQALEQAIISQKPQLEKLIATTAHEKMPWFHGNISRDESEQTVLIGSKTNGKFLIRARDNNGSFALCLLHEGKVLHYRIDRDKTGKLSIPEGKKFDTLWQLVEHYSYKPDGLLRVLTVPCQKIGVQMGHPGSSNAHPVTWSPGGIISRIKSYSFPKPGHKKPPPPQGSRPESTVSFNPYEPTGGAWGPDRGLQREALPMDTEVYESPYADPEEIRPKEVYLDRKLLTLEDNELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLAEANVMQQLDNPYIVRMIGICEAESWMLVMEMAAWGPLNKYLQQNRHIKDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYAPECINYFKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGERMGCPPGCPREMYDLMFLCWTYDVENRPGFAAVELRLRNYYYDVVN", "length": 629 }, "evidence": [ { "id": "F1N9Y5", "url": "https://omabrowser.org/oma/group/F1N9Y5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 50, "go_terms": [ { "name": "leukocyte activation involved in immune response", "id": "GO:0002366", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002366", "evidence": [ { "database": "UniProtKB", "id": "F1N9Y5", "url": "https://www.uniprot.org/uniprotkb/F1N9Y5" } ], "pmid": "" }, { "name": "neutrophil activation involved in immune response", "id": "GO:0002283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002283", "evidence": [ { "database": "UniProtKB", "id": "F1N9Y5", "url": "https://www.uniprot.org/uniprotkb/F1N9Y5" } ], "pmid": "" }, { "name": "serotonin secretion by platelet", "id": "GO:0002554", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002554", "evidence": [ { "database": "UniProtKB", "id": "F1N9Y5", "url": "https://www.uniprot.org/uniprotkb/F1N9Y5" } ], "pmid": "" }, { "name": "regulation of platelet activation", "id": "GO:0010543", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010543", "evidence": [ { "database": "UniProtKB", "id": "F1N9Y5", "url": "https://www.uniprot.org/uniprotkb/F1N9Y5" } ], "pmid": "" }, { "name": "integrin-mediated signaling pathway", "id": "GO:0007229", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007229", "evidence": [ { "database": "UniProtKB", "id": "F1N9Y5", "url": "https://www.uniprot.org/uniprotkb/F1N9Y5" } ], "pmid": "" }, { "name": "peptidyl-tyrosine phosphorylation", "id": "GO:0018108", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0018108", "evidence": [ { "database": "UniProtKB", "id": "F1N9Y5", "url": "https://www.uniprot.org/uniprotkb/F1N9Y5" } ], "pmid": "" }, { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "F1N9Y5", "url": "https://www.uniprot.org/uniprotkb/F1N9Y5" } ], "pmid": "" }, { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "F1N9Y5", "url": "https://www.uniprot.org/uniprotkb/F1N9Y5" } ], "pmid": "" }, { "name": "positive regulation of cell adhesion mediated by integrin", "id": "GO:0033630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033630", "evidence": [ { "database": "UniProtKB", "id": "F1N9Y5", "url": "https://www.uniprot.org/uniprotkb/F1N9Y5" } ], "pmid": "" }, { "name": "positive regulation of bone resorption", "id": "GO:0045780", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045780", "evidence": [ { "database": "UniProtKB", "id": "F1N9Y5", "url": "https://www.uniprot.org/uniprotkb/F1N9Y5" } ], "pmid": "" }, { "name": "blood vessel morphogenesis", "id": "GO:0048514", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048514", "evidence": [ { "database": "UniProtKB", "id": "F1N9Y5", "url": "https://www.uniprot.org/uniprotkb/F1N9Y5" } ], "pmid": "" }, { "name": "adaptive immune response", "id": "GO:0002250", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002250", "evidence": [ { "database": "UniProtKB", "id": "F1N9Y5", "url": "https://www.uniprot.org/uniprotkb/F1N9Y5" } ], "pmid": "" }, { "name": "leukocyte cell-cell adhesion", "id": "GO:0007159", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007159", "evidence": [ { "database": "UniProtKB", "id": "F1N9Y5", "url": "https://www.uniprot.org/uniprotkb/F1N9Y5" } ], "pmid": "" }, { "name": "B cell receptor signaling pathway", "id": "GO:0050853", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050853", "evidence": [ { "database": "UniProtKB", "id": "F1N9Y5", "url": "https://www.uniprot.org/uniprotkb/F1N9Y5" } ], "pmid": "" }, { "name": "cellular response to hydrogen peroxide", "id": "GO:0070301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070301", "evidence": [ { "database": "UniProtKB", "id": "F1N9Y5", "url": "https://www.uniprot.org/uniprotkb/F1N9Y5" } ], "pmid": "" }, { "name": "defense response to bacterium", "id": "GO:0042742", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042742", "evidence": [ { "database": "UniProtKB", "id": "F1N9Y5", "url": "https://www.uniprot.org/uniprotkb/F1N9Y5" } ], "pmid": "" }, { "name": "regulation of ERK1 and ERK2 cascade", "id": "GO:0070372", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070372", "evidence": [ { "database": "UniProtKB", "id": "F1N9Y5", "url": "https://www.uniprot.org/uniprotkb/F1N9Y5" } ], "pmid": "" }, { "name": "regulation of superoxide anion generation", "id": "GO:0032928", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032928", "evidence": [ { "database": "UniProtKB", "id": "F1N9Y5", "url": "https://www.uniprot.org/uniprotkb/F1N9Y5" } ], "pmid": "" }, { "name": "regulation of neutrophil degranulation", "id": "GO:0043313", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043313", "evidence": [ { "database": "UniProtKB", "id": "F1N9Y5", "url": "https://www.uniprot.org/uniprotkb/F1N9Y5" } ], "pmid": "" }, { "name": "regulation of arachidonate secretion", "id": "GO:0090237", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090237", "evidence": [ { "database": "UniProtKB", "id": "F1N9Y5", "url": "https://www.uniprot.org/uniprotkb/F1N9Y5" } ], "pmid": "" }, { "name": "lymph vessel development", "id": "GO:0001945", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001945", "evidence": [ { "database": "UniProtKB", "id": "F1N9Y5", "url": "https://www.uniprot.org/uniprotkb/F1N9Y5" } ], "pmid": "" }, { "name": "cellular response to molecule of fungal origin", "id": "GO:0071226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071226", "evidence": [ { "database": "UniProtKB", "id": "F1N9Y5", "url": "https://www.uniprot.org/uniprotkb/F1N9Y5" } ], "pmid": "" }, { "name": "neutrophil chemotaxis", "id": "GO:0030593", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030593", "evidence": [ { "database": "UniProtKB", "id": "F1N9Y5", "url": "https://www.uniprot.org/uniprotkb/F1N9Y5" } ], "pmid": "" }, { "name": "regulation of platelet aggregation", "id": "GO:0090330", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090330", "evidence": [ { "database": "UniProtKB", "id": "F1N9Y5", "url": "https://www.uniprot.org/uniprotkb/F1N9Y5" } ], "pmid": "" }, { "name": "regulation of phagocytosis", "id": "GO:0050764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050764", "evidence": [ { "database": "UniProtKB", "id": "F1N9Y5", "url": "https://www.uniprot.org/uniprotkb/F1N9Y5" } ], "pmid": "" }, { "name": "macrophage activation involved in immune response", "id": "GO:0002281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002281", "evidence": [ { "database": "UniProtKB", "id": "F1N9Y5", "url": "https://www.uniprot.org/uniprotkb/F1N9Y5" } ], "pmid": "" }, { "name": "positive regulation of TORC1 signaling", "id": "GO:1904263", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904263", "evidence": [ { "database": "UniProtKB", "id": "F1N9Y5", "url": "https://www.uniprot.org/uniprotkb/F1N9Y5" } ], "pmid": "" }, { "name": "interleukin-3-mediated signaling pathway", "id": "GO:0038156", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038156", "evidence": [ { "database": "UniProtKB", "id": "F1N9Y5", "url": "https://www.uniprot.org/uniprotkb/F1N9Y5" } ], "pmid": "" }, { "name": "receptor internalization", "id": "GO:0031623", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031623", "evidence": [ { "database": "UniProtKB", "id": "F1N9Y5", "url": "https://www.uniprot.org/uniprotkb/F1N9Y5" } ], "pmid": "" }, { "name": "positive regulation of superoxide anion generation", "id": "GO:0032930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032930", "evidence": [ { "database": "UniProtKB", "id": "F1N9Y5", "url": "https://www.uniprot.org/uniprotkb/F1N9Y5" } ], "pmid": "" }, { "name": "cellular response to amyloid-beta", "id": "GO:1904646", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904646", "evidence": [ { "database": "UniProtKB", "id": "F1N9Y5", "url": "https://www.uniprot.org/uniprotkb/F1N9Y5" } ], "pmid": "" }, { "name": "positive regulation of interleukin-6 production", "id": "GO:0032755", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032755", "evidence": [ { "database": "UniProtKB", "id": "F1N9Y5", "url": "https://www.uniprot.org/uniprotkb/F1N9Y5" } ], "pmid": "" }, { "name": "apoptotic signaling pathway", "id": "GO:0097190", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097190", "evidence": [ { "database": "UniProtKB", "id": "F1N9Y5", "url": "https://www.uniprot.org/uniprotkb/F1N9Y5" } ], "pmid": "" }, { "name": "positive regulation of protein-containing complex assembly", "id": "GO:0031334", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031334", "evidence": [ { "database": "UniProtKB", "id": "F1N9Y5", "url": "https://www.uniprot.org/uniprotkb/F1N9Y5" } ], "pmid": "" }, { "name": "positive regulation of tumor necrosis factor production", "id": "GO:0032760", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032760", "evidence": [ { "database": "UniProtKB", "id": "F1N9Y5", "url": "https://www.uniprot.org/uniprotkb/F1N9Y5" } ], "pmid": "" }, { "name": "positive regulation of interleukin-8 production", "id": "GO:0032757", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032757", "evidence": [ { "database": "UniProtKB", "id": "F1N9Y5", "url": "https://www.uniprot.org/uniprotkb/F1N9Y5" } ], "pmid": "" }, { "name": "positive regulation of receptor internalization", "id": "GO:0002092", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002092", "evidence": [ { "database": "UniProtKB", "id": "F1N9Y5", "url": "https://www.uniprot.org/uniprotkb/F1N9Y5" } ], "pmid": "" }, { "name": "positive regulation of monocyte chemotactic protein-1 production", "id": "GO:0071639", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071639", "evidence": [ { "database": "UniProtKB", "id": "F1N9Y5", "url": "https://www.uniprot.org/uniprotkb/F1N9Y5" } ], "pmid": "" }, { "name": "regulation of tumor necrosis factor-mediated signaling pathway", "id": "GO:0010803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010803", "evidence": [ { "database": "UniProtKB", "id": "F1N9Y5", "url": "https://www.uniprot.org/uniprotkb/F1N9Y5" } ], "pmid": "" }, { "name": "positive regulation of B cell differentiation", "id": "GO:0045579", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045579", "evidence": [ { "database": "UniProtKB", "id": "F1N9Y5", "url": "https://www.uniprot.org/uniprotkb/F1N9Y5" } ], "pmid": "" }, { "name": "positive regulation of type I interferon production", "id": "GO:0032481", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032481", "evidence": [ { "database": "UniProtKB", "id": "F1N9Y5", "url": "https://www.uniprot.org/uniprotkb/F1N9Y5" } ], "pmid": "" }, { "name": "positive regulation of interleukin-10 production", "id": "GO:0032733", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032733", "evidence": [ { "database": "UniProtKB", "id": "F1N9Y5", "url": "https://www.uniprot.org/uniprotkb/F1N9Y5" } ], "pmid": "" }, { "name": "stimulatory C-type lectin receptor signaling pathway", "id": "GO:0002223", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002223", "evidence": [ { "database": "UniProtKB", "id": "F1N9Y5", "url": "https://www.uniprot.org/uniprotkb/F1N9Y5" } ], "pmid": "" }, { "name": "cellular response to lipid", "id": "GO:0071396", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071396", "evidence": [ { "database": "UniProtKB", "id": "F1N9Y5", "url": "https://www.uniprot.org/uniprotkb/F1N9Y5" } ], "pmid": "" }, { "name": "positive regulation of interleukin-4 production", "id": "GO:0032753", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032753", "evidence": [ { "database": "UniProtKB", "id": "F1N9Y5", "url": "https://www.uniprot.org/uniprotkb/F1N9Y5" } ], "pmid": "" }, { "name": "cellular response to low-density lipoprotein particle stimulus", "id": "GO:0071404", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071404", "evidence": [ { "database": "UniProtKB", "id": "F1N9Y5", "url": "https://www.uniprot.org/uniprotkb/F1N9Y5" } ], "pmid": "" }, { "name": "positive regulation of interleukin-12 production", "id": "GO:0032735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032735", "evidence": [ { "database": "UniProtKB", "id": "F1N9Y5", "url": "https://www.uniprot.org/uniprotkb/F1N9Y5" } ], "pmid": "" }, { "name": "amyloid-beta clearance", "id": "GO:0097242", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097242", "evidence": [ { "database": "UniProtKB", "id": "F1N9Y5", "url": "https://www.uniprot.org/uniprotkb/F1N9Y5" } ], "pmid": "" }, { "name": "cell surface pattern recognition receptor signaling pathway", "id": "GO:0002752", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002752", "evidence": [ { "database": "UniProtKB", "id": "F1N9Y5", "url": "https://www.uniprot.org/uniprotkb/F1N9Y5" } ], "pmid": "" }, { "name": "positive regulation of cold-induced thermogenesis", "id": "GO:0120162", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120162", "evidence": [ { "database": "UniProtKB", "id": "F1N9Y5", "url": "https://www.uniprot.org/uniprotkb/F1N9Y5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 13, "go_terms": [ { "name": "protein tyrosine kinase activity", "id": "GO:0004713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004713", "evidence": [ { "database": "UniProtKB", "id": "F1N9Y5", "url": "https://www.uniprot.org/uniprotkb/F1N9Y5" } ], "pmid": "" }, { "name": "non-membrane spanning protein tyrosine kinase activity", "id": "GO:0004715", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004715", "evidence": [ { "database": "UniProtKB", "id": "F1N9Y5", "url": "https://www.uniprot.org/uniprotkb/F1N9Y5" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "F1N9Y5", "url": "https://www.uniprot.org/uniprotkb/F1N9Y5" } ], "pmid": "" }, { "name": "phosphotyrosine residue binding", "id": "GO:0001784", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001784", "evidence": [ { "database": "UniProtKB", "id": "F1N9Y5", "url": "https://www.uniprot.org/uniprotkb/F1N9Y5" } ], "pmid": "" }, { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "F1N9Y5", "url": "https://www.uniprot.org/uniprotkb/F1N9Y5" } ], "pmid": "" }, { "name": "integrin binding", "id": "GO:0005178", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005178", "evidence": [ { "database": "UniProtKB", "id": "F1N9Y5", "url": "https://www.uniprot.org/uniprotkb/F1N9Y5" } ], "pmid": "" }, { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "F1N9Y5", "url": "https://www.uniprot.org/uniprotkb/F1N9Y5" } ], "pmid": "" }, { "name": "SH2 domain binding", "id": "GO:0042169", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042169", "evidence": [ { "database": "UniProtKB", "id": "F1N9Y5", "url": "https://www.uniprot.org/uniprotkb/F1N9Y5" } ], "pmid": "" }, { "name": "scaffold protein binding", "id": "GO:0097110", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097110", "evidence": [ { "database": "UniProtKB", "id": "F1N9Y5", "url": "https://www.uniprot.org/uniprotkb/F1N9Y5" } ], "pmid": "" }, { "name": "phospholipase binding", "id": "GO:0043274", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043274", "evidence": [ { "database": "UniProtKB", "id": "F1N9Y5", "url": "https://www.uniprot.org/uniprotkb/F1N9Y5" } ], "pmid": "" }, { "name": "phosphatase binding", "id": "GO:0019902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019902", "evidence": [ { "database": "UniProtKB", "id": "F1N9Y5", "url": "https://www.uniprot.org/uniprotkb/F1N9Y5" } ], "pmid": "" }, { "name": "Toll-like receptor binding", "id": "GO:0035325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035325", "evidence": [ { "database": "UniProtKB", "id": "F1N9Y5", "url": "https://www.uniprot.org/uniprotkb/F1N9Y5" } ], "pmid": "" }, { "name": "interleukin-15 receptor binding", "id": "GO:0016170", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016170", "evidence": [ { "database": "UniProtKB", "id": "F1N9Y5", "url": "https://www.uniprot.org/uniprotkb/F1N9Y5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1N9Y5", "url": "https://www.uniprot.org/uniprotkb/F1N9Y5" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1N9Y5", "url": "https://www.uniprot.org/uniprotkb/F1N9Y5" } ], "pmid": "" }, { "name": "early phagosome", "id": "GO:0032009", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032009", "evidence": [ { "database": "UniProtKB", "id": "F1N9Y5", "url": "https://www.uniprot.org/uniprotkb/F1N9Y5" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1N9Y5", "url": "https://www.uniprot.org/uniprotkb/F1N9Y5" } ], "pmid": "" }, { "name": "T cell receptor complex", "id": "GO:0042101", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042101", "evidence": [ { "database": "UniProtKB", "id": "F1N9Y5", "url": "https://www.uniprot.org/uniprotkb/F1N9Y5" } ], "pmid": "" }, { "name": "B cell receptor complex", "id": "GO:0019815", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019815", "evidence": [ { "database": "UniProtKB", "id": "F1N9Y5", "url": "https://www.uniprot.org/uniprotkb/F1N9Y5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 18, "end_pos": 20, "annotation": "n_glycosylation_sequon" }, { "start_pos": 199, "end_pos": 201, "annotation": "n_glycosylation_sequon" }, { "start_pos": 340, "end_pos": 342, "annotation": "n_glycosylation_sequon" }, { "start_pos": 384, "end_pos": 386, "annotation": "n_glycosylation_sequon" }, { "start_pos": 448, "end_pos": 450, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "10596", "name": "", "equation": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V1ADF0-1", "F1N9Y5-1", "A0A8V0XQG0-1", "A0A8V0Y9A0-1", "A0A8V1AFM7-1", "A0A8V0Z0R8-1", "A0A8V0Z4B2-1", "A0A8V0ZBN6-1", "P09324-1", "A0A8V0XHW1-1", "A0A8V0YW12-1", "A0A8V0YUJ4-1", "A0A8V0ZSN8-1", "F1NVF2-1", "A0A8V1AKW4-1", "A0A8V0XB17-1", "A0A8V0ZC34-1", "A0A8V0YYC1-1", "A0A8V0ZND5-1", "A0A8V1ACF7-1", "A0A8V0ZP30-1", "E1BTE1-1", "Q07497-1", "A0A8V0X6E7-1", "F1NCL8-1", "A0A8V0XNF4-1", "A0A8V0XN86-1", "A0A8V0YEV0-1", "A0A8V0XQ80-1", "A0A8V0XZ82-1", "A0A8V0YZE5-1", "A0A8V0YYZ7-1", "A0A8V0YCV8-1", "A0A8V0YGR1-1", "A0A8V0YNY4-1", "A0A8V0YXM5-1", "A0A8V0YXZ9-1", "A0A3Q2UKD3-1", "A0A8V0YIT6-1", "A0A8V0YIV6-1", "R4GJW5-1", "A0A8V1A3N1-1", "A0A8V1A9R2-1", "A0A8V0ZE65-1", "A0A8V0ZER1-1", "A0A8V0ZXS7-1", "A0A8V1A7N1-1", "H9KZZ1-1", "F1NQL9-1", "A0A8V1ABP4-1", "F1NZY8-1", "Q02977-1", "A0A1D5PD64-1", "A0A8V0ZDU6-1", "A0A3Q2U1T2-1", "R4GJB8-1", "A0A3Q2U639-1", "A0A8V0X5W9-1", "E1C7Z1-1", "A0A8V0Y7Y3-1", "Q5ZIU3-1", "A0A8V0YPR4-1", "A0A8V0YT43-1", "A0A8V0Z3S3-1", "A0A8V0YJJ1-1", "A0A8V0YKP8-1", "A0A8V0YZ74-1", "A0A8V0ZWV8-1", "A0A8V1A069-1", "A0A8V1A7E0-1", "A0A8V1AEL3-1", "E1BTT3-1", "F1N996-1", "H9KZZ2-1", "E1C2C8-1", "Q05876-1", "Q90891-1", "O42422-1", "P00523-1", "P08941-1", "P13387-1", "P18460-1", "P18461-1", "P21804-1", "P28693-1", "P29318-1", "P42683-1", "P54755-1", "Q00944-1", "Q07494-1", "Q07496-1", "Q07498-1", "Q08156-1", "Q6XUX0-1", "Q75R65-1", "Q8AXY6-1", "Q8JH64-1", "Q8QHL3-1", "Q91009-1", "Q91044-1", "Q91987-1", "Q98949-1", "Q9PUF6-1", "F1NW21-1", "A0A8V0YLC3-1", "A0A8V0Z7L6-1", "F1NJX6-1", "A0A8V0YUC4-1", "F1NUX4-1", "A0A8V1A2E6-1", "E1BX69-1", "A0A8V0XPF0-1", "A0A8V0XFC9-1", "A0A8V0XBZ6-1", "A0A8V0ZRU7-1", "A0A8V0ZXD3-1", "A0A8V0YYI3-1", "A0A8V0YWW2-1", "A0A8V0YZP9-1", "A0A8V0YRJ8-1", "F1NLR7-1", "A0A8V0XCY6-1", "A0A8V1AMK9-1", "A0A8V0Z189-1", "P41239-1" ], "evidence": [ { "id": "10596", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/10596" } ] }, { "id": "R-GGA-1112666", "name": "BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A1D5PHP4-1", "F1N9Y5-1", "A0A8V0YUJ4-1" ], "evidence": [ { "id": "R-GGA-1112666", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1112666" } ] }, { "id": "R-GGA-2029268", "name": "Phosphorylation and activation of PLCG", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [ "R-ALL-179838" ], "output_participant_list": [], "enzyme_list": [ "A0A1D5PHP4-1", "A0A8V0ZHR0-1", "F1N9Y5-1" ], "evidence": [ { "id": "R-GGA-2029268", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2029268" } ] }, { "id": "R-GGA-2029270", "name": "Recruitment of PLCgamma to membrane", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A1D5PHP4-1", "A0A8V0ZHR0-1", "F1N9Y5-1" ], "evidence": [ { "id": "R-GGA-2029270", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2029270" } ] }, { "id": "R-GGA-2029271", "name": "PI3K phosphorylates PIP2 to PIP3", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1N9Y5-1" ], "evidence": [ { "id": "R-GGA-2029271", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2029271" } ] }, { "id": "R-GGA-2029272", "name": "Release of PLCG from FCGR", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A1D5PHP4-1", "A0A8V0ZHR0-1", "F1N9Y5-1" ], "evidence": [ { "id": "R-GGA-2029272", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2029272" } ] }, { "id": "R-GGA-2029273", "name": "PI3K binds to p-6Y-SYK", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1N9Y5-1" ], "evidence": [ { "id": "R-GGA-2029273", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2029273" } ] }, { "id": "R-GGA-2029451", "name": "Activation of RAC1 by VAV", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0Z8U4-1", "F1N9Y5-1" ], "evidence": [ { "id": "R-GGA-2029451", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2029451" } ] }, { "id": "R-GGA-2029453", "name": "Phosphorylation of VAV", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1N9Y5-1" ], "evidence": [ { "id": "R-GGA-2029453", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2029453" } ] }, { "id": "R-GGA-2029458", "name": "Recruitment of VAV1 to p-6Y-SYK", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1N9Y5-1" ], "evidence": [ { "id": "R-GGA-2029458", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2029458" } ] }, { "id": "R-GGA-2029467", "name": "Activation of RAC1 by CRKII:DOCK180:ELMO", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0Z8U4-1", "F1N9Y5-1" ], "evidence": [ { "id": "R-GGA-2029467", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2029467" } ] }, { "id": "R-GGA-2197697", "name": "Recruitment of CRKII:DOCK180:ELMO complex to FCGR", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1N9Y5-1" ], "evidence": [ { "id": "R-GGA-2197697", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2197697" } ] }, { "id": "R-GGA-2454240", "name": "Recruitment of SYK to p-FCERI gamma subunit", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XHW1-1", "F1N9Y5-1" ], "evidence": [ { "id": "R-GGA-2454240", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2454240" } ] }, { "id": "R-GGA-2730833", "name": "Phosphorylation of TEC kinases by p-SYK", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XHW1-1", "A0A1D5PHP4-1", "A0A8V0ZHR0-1", "F1NZY8-1", "A0A8V0YYC1-1", "F1N9Y5-1", "A0A8V0YJJ1-1", "A0A8V0YUJ4-1" ], "evidence": [ { "id": "R-GGA-2730833", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2730833" } ] }, { "id": "R-GGA-2730851", "name": "Phosphorylation of SLP-76 by p-SYK", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XHW1-1", "A0A1D5PHP4-1", "A0A8V0ZHR0-1", "F1N9Y5-1" ], "evidence": [ { "id": "R-GGA-2730851", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2730851" } ] }, { "id": "R-GGA-2730884", "name": "Phosphorylation of NTAL by p-SYK/Lyn", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [ "R-GGA-2685635" ], "output_participant_list": [ "R-GGA-2685597" ], "enzyme_list": [ "A0A8V0XHW1-1", "F1N9Y5-1" ], "evidence": [ { "id": "R-GGA-2730884", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2730884" } ] }, { "id": "R-GGA-2730886", "name": "Phosphorylation of SHC by SYK kinase", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [ "R-GGA-1169488" ], "output_participant_list": [ "R-GGA-1433505" ], "enzyme_list": [ "A0A8V0XHW1-1", "F1N9Y5-1" ], "evidence": [ { "id": "R-GGA-2730886", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2730886" } ] }, { "id": "R-GGA-429415", "name": "SYK binds to integrin alphaIIb beta3", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q5ZHX1-1", "F1NSA8-1", "A0A8V0ZDU6-1", "F1N9Y5-1" ], "evidence": [ { "id": "R-GGA-429415", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-429415" } ] }, { "id": "R-GGA-429441", "name": "SYK activation by SRC", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q5ZHX1-1", "F1NSA8-1", "A0A8V0ZDU6-1", "F1N9Y5-1" ], "evidence": [ { "id": "R-GGA-429441", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-429441" } ] }, { "id": "R-GGA-429449", "name": "Syk activation leads to SLP-76 activation", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [ "R-GGA-202306" ], "output_participant_list": [ "R-GGA-202175" ], "enzyme_list": [ "F1N9Y5-1" ], "evidence": [ { "id": "R-GGA-429449", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-429449" } ] }, { "id": "R-GGA-5621363", "name": "SYK phosphorylates PLCG2 in p-6Y-SYK:p-Y65,Y76-FCER1G:PLCG2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A1D5PHP4-1", "F1N9Y5-1" ], "evidence": [ { "id": "R-GGA-5621363", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5621363" } ] }, { "id": "R-GGA-879917", "name": "CBL, GRB2, FYN and PI3K p85 subunit are constitutively associated", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XHW1-1", "A0A8V0ZY53-1", "F1NHX1-1", "A0A8V0YT43-1", "A0A3Q2U639-1", "F1N9Y5-1", "P09324-1" ], "evidence": [ { "id": "R-GGA-879917", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-879917" } ] }, { "id": "R-GGA-912627", "name": "CBL ubiquitinates PI3K", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XHW1-1", "A0A8V0ZY53-1", "F1NHX1-1", "A0A8V0YT43-1", "A0A3Q2U639-1", "F1N9Y5-1", "P09324-1" ], "evidence": [ { "id": "R-GGA-912627", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-912627" } ] }, { "id": "R-GGA-9607039", "name": "LYN,SYK phosphorylate BTK", "equation": "", "summary": "LYN and activated (phosphorylated) SYK phosphorylate BTK on tyrosine-549 (Kurosaki and Kurosaki 1997).", "cellular_location": "plasma membrane", "input_participant_list": [ "R-GGA-433916" ], "output_participant_list": [ "R-GGA-9606997" ], "enzyme_list": [ "F1N9Y5-1", "Q8JH64-1" ], "evidence": [ { "id": "R-GGA-9607039", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9607039" } ] }, { "id": "R-GGA-9691421", "name": "BTK binds BTK inhibitors", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A1D5PHP4-1", "F1N9Y5-1", "A0A8V0YUJ4-1" ], "evidence": [ { "id": "R-GGA-9691421", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9691421" } ] }, { "id": "R-GGA-9707977", "name": "CSF3 dimer:2xK48polyUb-K655,p-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-Y-SYK:p-HCK:p-TYK2 translocates from the endocytic vesicle membrane to the lysosomal membrane", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "lysosomal membrane, endocytic vesicle membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0X5W9-1", "A0A8V0XHW1-1", "A0A8V0ZSN8-1", "A0A8V0YNY4-1", "A0A8V0YT43-1", "F1N9Y5-1" ], "evidence": [ { "id": "R-GGA-9707977", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9707977" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-179838", "participant_name": "PI(3,4,5)P3 [plasma membrane]", "crossref": [ { "id": "57836", "database": "ChEBI", "url": "" }, { "id": "C05981", "database": "COMPOUND", "url": "" } ] }, { "participant_id": "R-GGA-1169488", "participant_name": "SHC1 [cytosol]", "crossref": [ { "id": "A0A1D5NYP8", "database": "UniProt", "url": "" }, { "id": "ENSGALG00010027922", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALP00010041423", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALT00010067680", "database": "ENSEMBL", "url": "" }, { "id": "NP_001280209.1", "database": "RefSeq", "url": "" } ] }, { "participant_id": "R-GGA-1433505", "participant_name": "phospho-SHC1 [cytosol]", "crossref": [ { "id": "A0A1D5NYP8", "database": "UniProt", "url": "" }, { "id": "ENSGALP00010041423", "database": "ENSEMBL", "url": "" }, { "id": "NP_001280209.1", "database": "RefSeq", "url": "" }, { "id": "ENSGALT00010067680", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALG00010027922", "database": "ENSEMBL", "url": "" } ] }, { "participant_id": "R-GGA-202175", "participant_name": "phospho-LCP2 [cytosol]", "crossref": [ { "id": "ENSGALP00010014455", "database": "ENSEMBL", "url": "" }, { "id": "A0A8V0YA21", "database": "UniProt", "url": "" }, { "id": "ENSGALT00010025647", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALG00010010742", "database": "ENSEMBL", "url": "" } ] }, { "participant_id": "R-GGA-202306", "participant_name": "LCP2 [cytosol]", "crossref": [ { "id": "A0A8V0YA21", "database": "UniProt", "url": "" }, { "id": "ENSGALG00010010742", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALP00010014455", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALT00010025647", "database": "ENSEMBL", "url": "" } ] }, { "participant_id": "R-GGA-2685597", "participant_name": "phospho-LAT2 [plasma membrane]", "crossref": [ { "id": "ENSGALT00010071168", "database": "ENSEMBL", "url": "" }, { "id": "XP_004950573.3", "database": "RefSeq", "url": "" }, { "id": "ENSGALG00010029420", "database": "ENSEMBL", "url": "" }, { "id": "A0A8V1ACX2", "database": "UniProt", "url": "" }, { "id": "XP_040505979.1", "database": "RefSeq", "url": "" }, { "id": "XP_004950575.3", "database": "RefSeq", "url": "" }, { "id": "ENSGALP00010043859", "database": "ENSEMBL", "url": "" } ] }, { "participant_id": "R-GGA-2685635", "participant_name": "LAT2 [plasma membrane]", "crossref": [ { "id": "A0A8V1ACX2", "database": "UniProt", "url": "" }, { "id": "ENSGALG00010029420", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALP00010043859", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALT00010071168", "database": "ENSEMBL", "url": "" }, { "id": "XP_040505979.1", "database": "RefSeq", "url": "" }, { "id": "XP_004950573.3", "database": "RefSeq", "url": "" }, { "id": "XP_004950575.3", "database": "RefSeq", "url": "" } ] }, { "participant_id": "R-GGA-433916", "participant_name": "BTK [cytosol]", "crossref": [ { "id": "Q8JH64", "database": "UniProt", "url": "" } ] }, { "participant_id": "R-GGA-9606997", "participant_name": "p-Y549-BTK [cytosol]", "crossref": [ { "id": "Q8JH64", "database": "UniProt", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5PD64", "gene_name": "MAP2K3", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PD64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PD64" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A1D5PD64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PD64" } ] } ] }, { "uniprot_ac": "A0A1D5PHP4", "gene_name": "PLCG2", "activity": [ { "ec_number": "3.1.4.11", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + H2O = 1D-myo-inositol 1,4,5-trisphosphate + a 1,2-diacyl-sn-glycerol + H(+).", "evidence": [ { "id": "A0A1D5PHP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PHP4" } ] }, { "ec_number": "3.1.4.11", "activity": "", "evidence": [ { "id": "A0A1D5PHP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PHP4" } ] } ] }, { "uniprot_ac": "A0A3Q2U1T2", "gene_name": "BLK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2U1T2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U1T2" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A3Q2U1T2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U1T2" } ] } ] }, { "uniprot_ac": "A0A3Q2U639", "gene_name": "FYN", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2U639", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U639" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A3Q2U639", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U639" } ] } ] }, { "uniprot_ac": "A0A3Q2UKD3", "gene_name": "TEK", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2UKD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UKD3" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A3Q2UKD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UKD3" } ] } ] }, { "uniprot_ac": "A0A8V0X5W9", "gene_name": "TYK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X5W9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X5W9" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0X5W9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X5W9" } ] } ] }, { "uniprot_ac": "A0A8V0X6E7", "gene_name": "FES", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X6E7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X6E7" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0X6E7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X6E7" } ] } ] 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{ "uniprot_ac": "A0A8V0YZE5", "gene_name": "PDGFRB", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZE5" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0YZE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZE5" } ] } ] }, { "uniprot_ac": "A0A8V0YZP9", "gene_name": "EPHB2", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZP9" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0YZP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZP9" } ] } ] }, { "uniprot_ac": "A0A8V0Z0R8", "gene_name": "LCK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z0R8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0R8" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0Z0R8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0R8" } ] } ] }, { "uniprot_ac": "A0A8V0Z189", "gene_name": "PKDCCA", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z189", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z189" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0Z189", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z189" } ] } ] }, { "uniprot_ac": "A0A8V0Z3S3", "gene_name": "ALK", "activity": [ { "ec_number": "2.7.10.1", "activity": 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"ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0ZDU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDU6" } ] } ] }, { "uniprot_ac": "A0A8V0ZE65", "gene_name": "NTRK3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZE65", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE65" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0ZE65", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE65" } ] } ] }, { "uniprot_ac": "A0A8V0ZER1", "gene_name": "IGF1R", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZER1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZER1" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0ZER1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZER1" } ] } ] }, { "uniprot_ac": "A0A8V0ZHR0", "gene_name": "PLCG1", "activity": [ { "ec_number": "3.1.4.11", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + H2O = 1D-myo-inositol 1,4,5-trisphosphate + a 1,2-diacyl-sn-glycerol + H(+).", "evidence": [ { "id": "A0A8V0ZHR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHR0" } ] }, { "ec_number": "3.1.4.11", "activity": "", "evidence": [ { "id": "A0A8V0ZHR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHR0" } ] } ] }, { "uniprot_ac": "A0A8V0ZND5", "gene_name": "CSK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZND5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZND5" } ] }, { "ec_number": "2.7.10.2", "activity": "", 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"url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRU7" } ] } ] }, { "uniprot_ac": "A0A8V0ZSN8", "gene_name": "JAK1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZSN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSN8" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0ZSN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSN8" } ] } ] }, { "uniprot_ac": "A0A8V0ZWV8", "gene_name": "TIE1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZWV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWV8" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0ZWV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWV8" } ] } ] }, { "uniprot_ac": "A0A8V0ZXD3", "gene_name": "EPHA4", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZXD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXD3" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0ZXD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXD3" } ] } ] }, { "uniprot_ac": "A0A8V0ZXS7", "gene_name": "ERBB2", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZXS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXS7" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0ZXS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXS7" } ] } ] }, { "uniprot_ac": "A0A8V0ZY53", "gene_name": "CBL", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZY53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZY53" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZY53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZY53" } ] } ] }, { "uniprot_ac": "A0A8V1A069", "gene_name": "TESK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A069", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A069" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1A069", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A069" } ] } ] }, { "uniprot_ac": "A0A8V1A2E6", "gene_name": "EPHB1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A2E6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2E6" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V1A2E6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2E6" } ] } ] }, { "uniprot_ac": "A0A8V1A3N1", "gene_name": "MST1R", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A3N1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3N1" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V1A3N1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3N1" } ] } ] }, { "uniprot_ac": "A0A8V1A7E0", "gene_name": "DYRK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1A7E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E0" } ] } ] }, { "uniprot_ac": "A0A8V1A7N1", "gene_name": "ERBB3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7N1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7N1" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V1A7N1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7N1" } ] } ] }, { "uniprot_ac": "A0A8V1A9R2", "gene_name": "JAK3", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A9R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9R2" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V1A9R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9R2" } ] } ] }, { "uniprot_ac": "A0A8V1ABP4", "gene_name": "DSTYK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP4" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1ABP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP4" } ] } ] }, { "uniprot_ac": "A0A8V1ACF7", "gene_name": "ABL1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF7" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V1ACF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF7" } ] } ] }, { "uniprot_ac": "A0A8V1ADF0", "gene_name": "MAP2K2", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF0" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V1ADF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF0" } ] } ] }, { "uniprot_ac": "A0A8V1AEL3", "gene_name": "ZAP70", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AEL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEL3" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V1AEL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEL3" } ] } ] }, { "uniprot_ac": "A0A8V1AFM7", "gene_name": "INSR", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AFM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFM7" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V1AFM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFM7" } ] } ] }, { "uniprot_ac": "A0A8V1AKW4", "gene_name": "MAP2K4", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AKW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKW4" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V1AKW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKW4" } ] } ] }, { "uniprot_ac": "A0A8V1AMK9", "gene_name": "BAZ1B", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AMK9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK9" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V1AMK9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK9" } ] } ] }, { "uniprot_ac": "E1BTE1", "gene_name": "WEE2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BTE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BTE1" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "E1BTE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BTE1" } ] } ] }, { "uniprot_ac": "E1BTT3", "gene_name": "BMX", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BTT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BTT3" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "E1BTT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BTT3" } ] } ] }, { "uniprot_ac": "E1BX69", "gene_name": "EIF2AK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BX69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BX69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BX69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BX69" } ] } ] }, { "uniprot_ac": "E1C2C8", "gene_name": "MATK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C2C8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2C8" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "E1C2C8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2C8" } ] } ] }, { "uniprot_ac": "E1C7Z1", "gene_name": "FER", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C7Z1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C7Z1" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "E1C7Z1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C7Z1" } ] } ] }, { "uniprot_ac": "F1N996", "gene_name": "PTK6", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N996", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N996" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F1N996", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N996" } ] } ] }, { "uniprot_ac": "F1N9Y5", "gene_name": "SYK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N9Y5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N9Y5" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F1N9Y5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N9Y5" } ] } ] }, { "uniprot_ac": "F1NCL8", "gene_name": "FGFR4", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NCL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCL8" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1NCL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCL8" } ] } ] }, { "uniprot_ac": "F1NHX1", "gene_name": "PIK3CD", "activity": [ { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "F1NHX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NHX1" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "F1NHX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NHX1" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "F1NHX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NHX1" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "F1NHX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NHX1" } ] } ] }, { "uniprot_ac": "F1NJX6", "gene_name": "EPHA3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NJX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJX6" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1NJX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJX6" } ] } ] }, { "uniprot_ac": "F1NLR7", "gene_name": "CLK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NLR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLR7" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "F1NLR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLR7" } ] } ] }, { "uniprot_ac": "F1NQL9", "gene_name": "ROS1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NQL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NQL9" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1NQL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NQL9" } ] } ] }, { "uniprot_ac": "F1NSA8", "gene_name": "RAP1A", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "F1NSA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NSA8" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "F1NSA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NSA8" } ] } ] }, { "uniprot_ac": "F1NUX4", "gene_name": "MTOR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NUX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NUX4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NUX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NUX4" } ] } ] }, { "uniprot_ac": "F1NVF2", "gene_name": "MAP2K6", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NVF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVF2" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "F1NVF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVF2" } ] } ] }, { "uniprot_ac": "F1NW21", "gene_name": "KDR", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NW21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NW21" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1NW21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NW21" } ] } ] }, { "uniprot_ac": "F1NZY8", "gene_name": "TEC", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NZY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NZY8" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F1NZY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NZY8" } ] } ] }, { "uniprot_ac": "H9KZZ1", "gene_name": "NTRK1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "H9KZZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H9KZZ1" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "H9KZZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H9KZZ1" } ] } ] }, { "uniprot_ac": "H9KZZ2", "gene_name": "INSRR", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "H9KZZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H9KZZ2" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "H9KZZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H9KZZ2" } ] } ] }, { "uniprot_ac": "O42422", "gene_name": "EPHA7", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "O42422", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O42422" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "O42422", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O42422" } ] } ] }, { "uniprot_ac": "P00523", "gene_name": "SRC", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "P00523", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00523" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "P00523", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00523" } ] } ] }, { "uniprot_ac": "P08941", "gene_name": "ROS1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "P08941", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P08941" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "P08941", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P08941" } ] } ] }, { "uniprot_ac": "P09324", "gene_name": "YES1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "P09324", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P09324" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "P09324", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P09324" } ] } ] }, { "uniprot_ac": "P13387", "gene_name": "EGFR", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "P13387", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13387" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "P13387", "database": "UniProtKB", 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"https://alphafold.ebi.ac.uk/entry/F1N9Y5" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1N9Y5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N9Y5" }, { "id": "PRU00159", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00159" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Protein kinase", "eco_id": "ECO_0000255", "start_pos": 349, "end_pos": 613, "start_aa": "Thr", "end_aa": "His", "glycosite_overlap": "" }, { "evidence": [ { "id": "F1N9Y5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N9Y5" }, { "id": "PRU00191", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00191" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SH2 1", "eco_id": "ECO_0000255", "start_pos": 14, "end_pos": 106, "start_aa": "Tyr", "end_aa": "Phe", "glycosite_overlap": "" }, { "evidence": [ { "id": "F1N9Y5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N9Y5" }, { "id": "PRU00191", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00191" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SH2 2", "eco_id": "ECO_0000255", "start_pos": 167, "end_pos": 258, "start_aa": "Trp", "end_aa": "Cys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.7.10.2", "ec_name": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "2.7.10.2", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2" }, { "id": "2.7.10.2", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.7.10.2" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 278 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 18, "end_pos": 20 }, { "start_pos": 199, "end_pos": 201 }, { "start_pos": 340, "end_pos": 342 }, { "start_pos": 384, "end_pos": 386 }, { "start_pos": 448, "end_pos": 450 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": 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"total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 9 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "P49147-1", "uniprot_ac": "P49147", "uniprot_id": "PA24A_CHICK", "mass": { "chemical_mass": 84979.0, "monoisotopic_mass": 84979.0 }, "refseq": { "ac": "NP_990754", "name": "cytosolic phospholipase A2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990754" }, "gene_names": [ { "name": "PLA2G4A", "type": "recommended", "evidence": [ { "id": "P49147", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P49147" } ] }, { "name": "CPLA2", "type": "synonym", "evidence": [ { "id": "P49147", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P49147" } ] }, { "name": "PLA2G4A", "type": "synonym", "evidence": [ { "id": "NP_990754", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990754" } ] }, { "name": "PLA2G4", "type": "synonym", "evidence": [ { "id": "NP_990754", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990754" }, { "id": "P49147", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P49147" } ] } ], "protein_names": [ { "name": "Cytosolic phospholipase A2", "type": "recommended", "evidence": [ { "id": "P49147", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P49147/entry#names_and_taxonomy" } ] }, { "name": "Phosphatidylcholine 2-acylhydrolase", "type": "synonym", "evidence": [ { "id": "P49147", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P49147/entry#names_and_taxonomy" } ] }, { "name": "Phospholipase A2 group IVA", "type": "synonym", "evidence": [ { "id": "P49147", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P49147/entry#names_and_taxonomy" } ] }, { "name": "cPLA2", "type": "synonym", "evidence": [ { "id": "NP_990754", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990754" }, { "id": "P49147", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P49147/entry#names_and_taxonomy" } ] }, { "name": "cytosolic phospholipase A2", "type": "synonym", "evidence": [ { "id": "NP_990754", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990754" } ] }, { "name": "phospholipase A2, group IVA (cytosolic, calcium-dependent)", "type": "synonym", "evidence": [ { "id": "NP_990754", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990754" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: U10329.1, SRR13267659.233825.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from U10329.1.", "evidence": [ { "database": "RefSeq", "id": "NP_990754", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990754" } ] }, { "annotation": "Selectively hydrolyzes arachidonyl phospholipids in the sn-2 position releasing arachidonic acid. Together with its lysophospholipid activity, it is implicated in the initiation of the inflammatory response.", "evidence": [ { "database": "UniProtKB", "id": "P49147", "url": "https://www.uniprot.org/uniprotkb/P49147#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "P49147", "url": "https://www.uniprot.org/uniprotkb/P49147" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PLA2G4A", "url": "https://www.uniprot.org/uniprotkb/P49147", "locus": { "chromosome": "8", "start_pos": 10031242, "end_pos": 10139649, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021027", "url": "https://www.ensembl.org/id/ENSGALG00010021027" } ] } } ], "crossref": [ { "id": "P49147", "url": "https://alphafold.ebi.ac.uk/entry/P49147", 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"database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-432142", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-432142", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-6811436", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6811436", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_990754", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990754", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "15177", "url": "https://www.rhea-db.org/rhea/15177", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "15801", "url": "https://www.rhea-db.org/rhea/15801", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A1D5NTC1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NTC1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5NTC1-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NTC1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZH03", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH03", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZH03-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH03-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P49147", "url": "https://www.uniprot.org/uniprotkb/P49147", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P49147-1", "url": "https://www.uniprot.org/uniprotkb/P49147-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSFIDPYQHIVVEHQYSHVFTVTVRKATNVTKGAIGDMLDTPDPYVELFIPSAPDCRKRTKHFNNDVNPVWNETFEFILDPNQDNVLEVTLMDANYVMDETLGMATFPISSLKLGEKKEVQLTFNNVTEMTLELSLEVCSSTDLRFSMALCDEEKKFRQQRKDNIMQSMKSFLGEENSKNLTTSRDVPVIAVLGSGGGFRAMVGFAGVMKALYESGVLDCATYIAGLSGSTWYMSTLYSHPDFPEKGPKEINQELMNSVSHNPLLLLTPQKVKRYIEALWNKKSSGQPVTFTDIFGMLIGETLIHNRMDTTLSDMKEKVSEAQCALPLFTCLHVKPDVSELMFADWVEFSPYEIGMAKYGTFMSPDLFGSKFFMGTVVKKYSENPLHFLMGVWGSAFSILFNRVLGVSNSQNKGPTMEEELENIRLKHLVSNDSSDSEDESQHPKGTENSEANEEYQNSSQESWVQRMLMALVGDSALFNTREGRAGKVHNFMLGLNLNSCYPLSPLADLLTQESVEEDELDAAVADPDEFERIYEPLDVKSKKIHIVDSGLTFNLPYPLILRPQRGVDLIISFDFSARPSDSSPPFKEILLAEKWAKMNKLPFPKIDPNVFDREGLKECYVFKPKDTSSEKDCPTIIHFVLANINFRKYKAPGLPRESKEEKDFADFDIFDDPNTPFSTFNFQYPNEAFKRLHDLMEFNTLNNLDVIKQAMMESIEYRKENPSRCSVSLSSVEARRFFNKNNLNNHT", "length": 748, "header": "sp|P49147-1|PA24A_CHICK Isoform 1 of Cytosolic phospholipase A2 OS=Gallus gallus OX=9031 GN=PLA2G4A PE=1 SV=1 CANONICAL=P49147-1" }, "isoforms": [ { "isoform_ac": "A0A1D5NTC1-1", "url": "https://www.uniprot.org/uniprotkb/P49147/entry#A0A1D5NTC1-1", "sequence": { "sequence": "MMLYPVEHQYSHVFTVTVRKATNVTKGAIGDMLDTPDPYVELFIPSAPDCRKRTKHFNNDVNPVWNETFEFILDPNQDNVLEVTLMDANYVMDETLGMATFPISSLKLGEKKEVQLTFNNVTEMTLELSLEVCSSTDLRFSMALCDEEKKFRQQRKDNIMQSMKSFLGEENSKNLTTSRDVPVIAVLGSGGGFRAMVGFAGVMKALYESGVLDCATYIAGLSGSTWYMSTLYSHPDFPEKGPKEINQELMNSVSHNPLLLLTPQKVKRYIEALWNKKSSGQPVTFTDIFGMLIGETLIHNRMDTTLSDMKEKVSEAQCALPLFTCLHVKPDVSELMFADWVEFSPYEIGMAKYGTFMSPDLFGSKFFMGTVVKKYSENPLHFLMGVWGSAFSILFNRVLGVSNSQNKGPTMEEELENIRLKHLVSNDSSDSEDESQHPKGTENSEANEEYQNSSQESWVQRMLMALVGDSALFNTREGRAGKVHNFMLGLNLNSCYPLSPLADLLTQESVEEDELDAAVADPDEFERIYEPLDVKSKKIHIVDSGLTFNLPYPLILRPQRGVDLIISFDFSARPSDSSPPFKEILLAEKWAKMNKLPFPKIDPNVFDREGLKECYVFKPKDTSSEKDCPTIIHFVLANINFRKYKAPGLPRESKEEKDFADFDIFDDPNTPFSTFNFQYPNEAFKRLHDLMEFNTLNNLDVIKQAMMESIEYRKENPSRCSVSLSSVEARRFFNKNNLNNHT", "length": 742, "header": "tr|A0A1D5NTC1-1|PA24A_CHICK Computationally mapped isoform of Cytosolic phospholipase A2 OS=Gallus gallus OX=9031 GN=PLA2G4A PE=1 SV=1 CANONICAL=P49147-1" }, "locus": { "chromosome": "8", "start_pos": 10090029, "end_pos": 10033725, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050877.1", "url": "https://www.ensembl.org/id/ENSGALT00010050877.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030068.1", "url": "https://www.ensembl.org/id/ENSGALP00010030068.1" } ] } }, { "isoform_ac": "A0A8V0ZH03-1", "url": "https://www.uniprot.org/uniprotkb/P49147/entry#A0A8V0ZH03-1", "sequence": { "sequence": "MSEVEHQYSHVFTVTVRKATNVTKGAIGDMLDTPDPYVELFIPSAPDCRKRTKHFNNDVNPVWNETFEFILDPNQDNVLEVTLMDANYVMDETLGMATFPISSLKLGEKKEVQLTFNNVTEMTLELSLEVCSSTDLRFSMALCDEEKKFRQQRKDNIMQSMKSFLGEENSKNLTTSRDVPVIAVLGSGGGFRAMVGFAGVMKALYESGVLDCATYIAGLSGSTWYMSTLYSHPDFPEKGPKEINQELMNSVSHNPLLLLTPQKVKRYIEALWNKKSSGQPVTFTDIFGMLIGETLIHNRMDTTLSDMKEKVSEAQCALPLFTCLHVKPDVSELMFADWVEFSPYEIGMAKYGTFMSPDLFGSKFFMGTVVKKYSENPLHFLMGVWGSAFSILFNRVLGVSNSQNKGPTMEEELENIRLKHLVSNDSSDSEDESQHPKGTENSEANEEYQNSSQESWVQRMLMALVGDSALFNTREGRAGKVHNFMLGLNLNSCYPLSPLADLLTQESVEEDELDAAVADPDEFERIYEPLDVKSKKIHIVDSGLTFNLPYPLILRPQRGVDLIISFDFSARPSDSSPPFKEILLAEKWAKMNKLPFPKIDPNVFDREGLKECYVFKPKDTSSEKDCPTIIHFVLANINFRKYKAPGLPRESKEEKDFADFDIFDDPNTPFSTFNFQYPNEAFKRLHDLMEFNTLNNLDVIKQAMMESIEYRKENPSRCSVSLSSVEARRFFNKNNLNNHT", "length": 740, "header": "tr|A0A8V0ZH03-1|PA24A_CHICK Computationally mapped isoform of Cytosolic phospholipase A2 OS=Gallus gallus OX=9031 GN=PLA2G4A PE=1 SV=1 CANONICAL=P49147-1" }, "locus": { "chromosome": "8", "start_pos": 10091233, "end_pos": 10033725, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050880.1", "url": "https://www.ensembl.org/id/ENSGALT00010050880.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030071.1", "url": "https://www.ensembl.org/id/ENSGALP00010030071.1" } ] } }, { "isoform_ac": "P49147-1", "url": "https://www.uniprot.org/uniprotkb/P49147/entry#P49147-1", "sequence": { "sequence": "MSFIDPYQHIVVEHQYSHVFTVTVRKATNVTKGAIGDMLDTPDPYVELFIPSAPDCRKRTKHFNNDVNPVWNETFEFILDPNQDNVLEVTLMDANYVMDETLGMATFPISSLKLGEKKEVQLTFNNVTEMTLELSLEVCSSTDLRFSMALCDEEKKFRQQRKDNIMQSMKSFLGEENSKNLTTSRDVPVIAVLGSGGGFRAMVGFAGVMKALYESGVLDCATYIAGLSGSTWYMSTLYSHPDFPEKGPKEINQELMNSVSHNPLLLLTPQKVKRYIEALWNKKSSGQPVTFTDIFGMLIGETLIHNRMDTTLSDMKEKVSEAQCALPLFTCLHVKPDVSELMFADWVEFSPYEIGMAKYGTFMSPDLFGSKFFMGTVVKKYSENPLHFLMGVWGSAFSILFNRVLGVSNSQNKGPTMEEELENIRLKHLVSNDSSDSEDESQHPKGTENSEANEEYQNSSQESWVQRMLMALVGDSALFNTREGRAGKVHNFMLGLNLNSCYPLSPLADLLTQESVEEDELDAAVADPDEFERIYEPLDVKSKKIHIVDSGLTFNLPYPLILRPQRGVDLIISFDFSARPSDSSPPFKEILLAEKWAKMNKLPFPKIDPNVFDREGLKECYVFKPKDTSSEKDCPTIIHFVLANINFRKYKAPGLPRESKEEKDFADFDIFDDPNTPFSTFNFQYPNEAFKRLHDLMEFNTLNNLDVIKQAMMESIEYRKENPSRCSVSLSSVEARRFFNKNNLNNHT", "length": 748, "header": "sp|P49147-1|PA24A_CHICK Isoform 1 of Cytosolic phospholipase A2 OS=Gallus gallus OX=9031 GN=PLA2G4A PE=1 SV=1 CANONICAL=P49147-1" }, "locus": { "chromosome": "8", "start_pos": 10095653, "end_pos": 10033725, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050885.1", "url": "https://www.ensembl.org/id/ENSGALT00010050885.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030076.1", "url": "https://www.ensembl.org/id/ENSGALP00010030076.1" } ] } } ], "glycosylation": [], "phosphorylation": [ { "start_pos": 505, "end_pos": 505, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine; by MAPK", "evidence": [ { "database": "UniProtKB", "id": "P49147", "url": "https://www.uniprot.org/uniprotkb/P49147" } ], "site_lbl": "Ser505" } ], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "Delineation of two functionally distinct domains of cytosolic phospholipase A2, a regulatory Ca(2+)-dependent lipid-binding domain and a Ca(2+)-independent catalytic domain.", "journal": "J. Biol. Chem.", "date": "1994", "authors": "Nalefski E A, Sultzman L A, Martin D M, Kriz R W, Towler P S, Knopf J L, Clark J D", "evidence": [ { "database": "UniProtKB", "id": "P49147", "url": "https://www.uniprot.org/uniprotkb/P49147" } ], "reference": [ { "type": "PubMed", "id": "8027085", "url": "https://glygen.org/publication/PubMed/8027085" } ] } ], "pathway": [ { "id": "gga:396394", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:396394", "resource": "KEGG Pathway" }, { "id": "R-GGA-111995", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-111995", "resource": "Reactome", "description": "phospho-PLA2 pathway" }, { "id": "R-GGA-1482788", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1482788", "resource": "Reactome", "description": "Acyl chain remodelling of PC" }, { "id": "R-GGA-1482798", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1482798", "resource": "Reactome", "description": "Acyl chain remodeling of CL" }, { "id": "R-GGA-1482801", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1482801", "resource": "Reactome", "description": "Acyl chain remodelling of PS" }, { "id": "R-GGA-1482839", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1482839", "resource": "Reactome", "description": "Acyl chain remodelling of PE" }, { "id": "R-GGA-1482922", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1482922", "resource": "Reactome", "description": "Acyl chain remodelling of PI" }, { "id": "R-GGA-1482925", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1482925", "resource": "Reactome", "description": "Acyl chain remodelling of PG" }, { "id": "R-GGA-1483115", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1483115", "resource": "Reactome", "description": "Hydrolysis of LPC" }, { "id": "R-GGA-1483166", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1483166", "resource": "Reactome", "description": "Synthesis of PA" }, { "id": "R-GGA-2142753", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2142753", "resource": "Reactome", "description": "Arachidonate metabolism" }, { "id": "R-GGA-418592", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-418592", "resource": "Reactome", "description": "ADP signalling through P2Y purinoceptor 1" }, { "id": "R-GGA-432142", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-432142", "resource": "Reactome", "description": "Platelet sensitization by LDL" }, { "id": "R-GGA-6811436", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6811436", "resource": "Reactome", "description": "COPI-independent Golgi-to-ER retrograde traffic" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1TRG4-1", "protein_name": "Phospholipase A2", "gene_name": "PLA2G4A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSFIDPYQHIIVEHHYSHKFTVVVLRATKVTKGAFGDMLDTPDPYVELFISSTPDSRKRTRHFNNDINPVWNETFEFILDPNQENTLEITLMDANYVMDETLGTATFPISSMKVGEKKEVPFIFNQVTEMILEMSLEVCSSPDLRFSMALCDEEKAFRQQRKENIKENMKKLLGPENSEGLCSTRDVPVVAILGSGGGFRAMVGFSGVMKALYESGILDCATYIAGLSGSTWYMSTLYSHPDFPEKGPEEINKELMNNVSHNPLLLLTPQKIKRYVESLWKKKSSGQPVTFTDIFGMLIGETLIHNRMNTTLSSLKEKVNAGQCPLPLFTCLHVKPDVSELMFADWVEFSPYEIGMAKYGTFMAPDLFGSKFFMGTIVKKYEENPLHFLMGVWGSAFSILFNRVLGVSGSQNKGSTMEEELENITAKHIVSNDSSDSDDESQERKGSENEEAEREYQNDNQASWVQRMLMALVSDSALFNTREGRAGKVHNFMLGLNLNTSYPMSPLRNFTTQESLDEDELDTAVADPDEFERIYEPLDVKSKKIHVVDSGLTFNLPYPLILRPQRGVDLIISFDFSARPSDSSPPFKELLLAEKWAKMNKLPFPKIDQNVFDREGLKECYVFKPKNPDVEKDCPTIIHFVLANINFRKYKAPGVPRETQEEKEIADFDIFDDPESPFSTFNFQYPNQAFKRLHDLMYFNTLNNIDVIKNAIVESIEYRRQNPSRCSVSLSSVEARRFFNKEFLNKPTA", "length": 749 }, "evidence": [ { "id": "P49147", "url": "https://omabrowser.org/oma/group/P49147/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A4IFJ5-1", "protein_name": "Cytosolic phospholipase A2", "gene_name": "PLA2G4A", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSFIDPYQHIIVEHHYSHKFTVVVLRATKVTKGTFGDMLDTPDPYVELFISSTPDSRKRTRHFNNDINPVWNETFEFILDPNQENILEITLMDANYVMDETLGTTTFPISSMKVGEKKQVPFIFNQVTEMILEMSLEVCSSPDLRFSMALCDQEKAFRQQRKENIKENMKKLLGPKNSEGLHSTRDVPVVAILGSGGGFRAMVGFSGVMKALYESGILDCATYIAGLSGSTWYMSTLYSHPDFPEKGPEEINKELMKNVSHNPLLLLTPQKIKRYVESLWRKKSSGQPVTFTDIFGMLIGETLIHNRMNTTLSSLKEKVNTGQCPLPLFTCLHVKPDVSELMFADWVEFSPFEIGMAKYGTFMAPDLFGSKFFMGTVVKKYEENPLHFLMGVWGSAFSILFNRVLGVSGSQSKGSTMEEELENITAKHIVSNDSSDSDDESQGPKGTEHEEAEREYQNDNQASWVQRMLMALVSDSALFNTREGRAGKVHNFMLGLNLNTSYPMSPLRDFTMQESLDEDELDAAVADPDEFEQIYEPLDVKSKKIHVVDSGLTFNLPYPLILRPQRGVDLIISFDFSARPSDSSPPFKELLLAEKWAKMNKLPFPKIDPYVFDREGLKECYVFKPKNPDVEKDCPTIIHFVLANINFRKYKAPGVPRETNEEKEIADFDIFDDPESPFSTFNFQYPNQAFKRLHDLMYFNTLNNIDVIKNAIVESIEYRRQNPSRCSVSLSSVEARRFFNKEFLSKPTA", "length": 749 }, "evidence": [ { "id": "P49147", "url": "https://omabrowser.org/oma/group/P49147/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3GWV5-1", "protein_name": "Phospholipase A2", "gene_name": "Pla2g4a", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSFIDPYQHIIVEHQYSHKFTVVVLSATKVTKGTFGDMLDTPDPYVELFISTTPDSRKRTRHFNNDINPVWNETFEFILDPNQENVLEITLMDANYIMDETLGTATFPVSSMKVGEKKEVPFIFNQVTEMILEMSLEVCSCPDLRFSMALCDQEKAFRQQRKENIKENMKKLLGPKKSEGLYSTRDVPVVAILGSGGGFRAMVGFSGVMKALYESGILDCATYIAGLSGSTWYMSTLYSHPDFPEKGPEEINEELMKNVSHNPLLLLTPQKVKRYVESLWKKKSSGQPVTFTDIFGMLIGETLIQNRMNTTLSSLKEKVNEARCPLPLFTCLHVKPDVSELMFADWVEFSPYEIGMAKYGTFMAPDLFGSKFFMGTVVKKYEENPLHFLMGVWGSAFSILFNRVLGVSGSQNKGSTMEEELENITAKHIVSNDSSDSDDEAQAPKGTENEDAEREYQNDNQASWVHRMLMALVSDSALFNTREGRAGKVHNFMLGLNLNTSYPLSPLRDLSSQDSFDDDELDAAVADPDEFERIYEPLDVKSKKIHVVDSGLTFNLPYPLILRPQRGVDLIISFDFSARPSDTSPPFKELLLAEKWAKMNKLPFPKIDPYVFDREGLKECYVFKPKNPDVENDCPTIIHFVLANINFRKYKAPGVPRETKEEKEIADFDIFDDPESPFSTFNFQYPNQAFKRLHDLMYFNTLNNIDVIKDAIVESIEYRRQNPSRCSVSLSNVEARKFFNKEFLSKPTA", "length": 749 }, "evidence": [ { "id": "P49147", "url": "https://omabrowser.org/oma/group/P49147/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P47712-1", "protein_name": "Cytosolic phospholipase A2", "gene_name": "PLA2G4A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSFIDPYQHIIVEHQYSHKFTVVVLRATKVTKGAFGDMLDTPDPYVELFISTTPDSRKRTRHFNNDINPVWNETFEFILDPNQENVLEITLMDANYVMDETLGTATFTVSSMKVGEKKEVPFIFNQVTEMVLEMSLEVCSCPDLRFSMALCDQEKTFRQQRKEHIRESMKKLLGPKNSEGLHSARDVPVVAILGSGGGFRAMVGFSGVMKALYESGILDCATYVAGLSGSTWYMSTLYSHPDFPEKGPEEINEELMKNVSHNPLLLLTPQKVKRYVESLWKKKSSGQPVTFTDIFGMLIGETLIHNRMNTTLSSLKEKVNTAQCPLPLFTCLHVKPDVSELMFADWVEFSPYEIGMAKYGTFMAPDLFGSKFFMGTVVKKYEENPLHFLMGVWGSAFSILFNRVLGVSGSQSRGSTMEEELENITTKHIVSNDSSDSDDESHEPKGTENEDAGSDYQSDNQASWIHRMIMALVSDSALFNTREGRAGKVHNFMLGLNLNTSYPLSPLSDFATQDSFDDDELDAAVADPDEFERIYEPLDVKSKKIHVVDSGLTFNLPYPLILRPQRGVDLIISFDFSARPSDSSPPFKELLLAEKWAKMNKLPFPKIDPYVFDREGLKECYVFKPKNPDMEKDCPTIIHFVLANINFRKYRAPGVPRETEEEKEIADFDIFDDPESPFSTFNFQYPNQAFKRLHDLMHFNTLNNIDVIKEAMVESIEYRRQNPSRCSVSLSNVEARRFFNKEFLSKPKA", "length": 749 }, "evidence": [ { "id": "P49147", "url": "https://omabrowser.org/oma/group/P49147/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P47713-1", "protein_name": "Cytosolic phospholipase A2", "gene_name": "Pla2g4a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSFIDPYQHIIVEHQYSHKFTVVVLRATKVTKGTFGDMLDTPDPYVELFISTTPDSRKRTRHFNNDINPVWNETFEFILDPNQENVLEITLMDANYVMDETLGTATFPVSSMKVGEKKEVPFIFNQVTEMILEMSLEVCSCPDLRFSMALCDQEKTFRQQRKENIKENMKKLLGPKKSEGLYSTRDVPVVAILGSGGGFRAMVGFSGVMKALYESGILDCATYIAGLSGSTWYMSTLYSHPDFPEKGPEEINEELMKNVSHNPLLLLTPQKVKRYVESLWKKKSSGQPVTFTDIFGMLIGETLIQNRMSMTLSSLKEKVNAARCPLPLFTCLHVKPDVSELMFADWVEFSPYEIGMAKYGTFMAPDLFGSKFFMGTVVKKYEENPLHFLMGVWGSAFSILFNRVLGVSGSQNKGSTMEEELENITAKHIVSNDSSDSDDEAQGPKGTENEEAEKEYQSDNQASWVHRMLMALVSDSALFNTREGRAGKVHNFMLGLNLNTSYPLSPLRDFSSQDSFDDELDAAVADPDEFERIYEPLDVKSKKIHVVDSGLTFNLPYPLILRPQRGVDLIISFDFSARPSDTSPPFKELLLAEKWAKMNKLPFPKIDPYVFDREGLKECYVFKPKNPDVEKDCPTIIHFVLANINFRKYKAPGVLRETKEEKEIADFDIFDDPESPFSTFNFQYPNQAFKRLHDLMYFNTLNNIDVIKDAIVESIEYRRQNPSRCSVSLSNVEARKFFNKEFLSKPTV", "length": 748 }, "evidence": [ { "id": "P49147", "url": "https://omabrowser.org/oma/group/P49147/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P50393-1", "protein_name": "Cytosolic phospholipase A2", "gene_name": "Pla2g4a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSFIDPYQHIIVEHQYSHKFTVVVLRATKVTKGTFGDMLDTPDPYVELFISTTPDSRKRTRHFNNDINPVWNETFEFILDPNQENVLEITLMDANYVMDETLGTATFPVSSMKVGEKKEVPFIFNQVTEMILEMSLEVCSCPDLRFSMALCDQEKTFRRQRKENIKENMKKLLGPKKSEGLYSTRDVPVVAILGSGGGFRAMVGFSGVMKALYESGILDCATYVAGLSGSTWYMSTLYSHPDFPEKGPEEINEELMKNVSHNPLLLLTPQKVKRYVESLWKKKSSGQPVTFTDIFGMLIGETLIQNRMSTTLSSLKEKVSAARCPLPLFTCLHVKPDVSELMFADWVEFSPYEIGMAKYGTFMTPDLFGSKFFMGTVVKKYEENPLHFLMGVWGSAFSILFNRVLGVSGSQNKGSTMEEELENITAKHIVSNDSSDSDDEAQGPKGTENEDAEREYQNDNQASWVHRMLMALVSDSALFNTREGRAGKEHNFMLGLNLNTSYPLSPLRDFSPQDSFDDDELDAAVADPDEFERIYEPLDVKSKKIHVVDSGLTFNLPYPLILRPQRGVDLIISFDFSARPSDTSPPFKELLLAEKWAKMNKLPFPKIDPYVFDREGLKECYVFKPKNPDVEKDCPTIIHFVLANINFRKYKAPGVLRETKEEKEIADFDIFDDPESPFSTFNFQYPNQAFKRLHDLMYFNTLNNIDVIKDAIVESIEYRRQNPSRCSVSLSNVEARKFFNKEFLSKPTAESI", "length": 752 }, "evidence": [ { "id": "P49147", "url": "https://omabrowser.org/oma/group/P49147/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 14, "go_terms": [ { "name": "platelet activating factor biosynthetic process", "id": "GO:0006663", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006663", "evidence": [ { "database": "UniProtKB", "id": "P49147", "url": "https://www.uniprot.org/uniprotkb/P49147" } ], "pmid": "" }, { "name": "positive regulation of macrophage activation", "id": "GO:0043032", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043032", "evidence": [ { "database": "UniProtKB", "id": "P49147", "url": "https://www.uniprot.org/uniprotkb/P49147" } ], "pmid": "" }, { "name": "phosphatidylcholine catabolic process", "id": "GO:0034638", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034638", "evidence": [ { "database": "UniProtKB", "id": "P49147", "url": "https://www.uniprot.org/uniprotkb/P49147" } ], "pmid": "" }, { "name": "arachidonate secretion", "id": "GO:0050482", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050482", "evidence": [ { "database": "UniProtKB", "id": "P49147", "url": "https://www.uniprot.org/uniprotkb/P49147" } ], "pmid": "" }, { "name": "phosphatidylcholine acyl-chain remodeling", "id": "GO:0036151", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036151", "evidence": [ { "database": "UniProtKB", "id": "P49147", "url": "https://www.uniprot.org/uniprotkb/P49147" } ], "pmid": "" }, { "name": "glycerophospholipid catabolic process", "id": "GO:0046475", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046475", "evidence": [ { "database": "UniProtKB", "id": "P49147", "url": "https://www.uniprot.org/uniprotkb/P49147" } ], "pmid": "" }, { "name": "leukotriene biosynthetic process", "id": "GO:0019370", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019370", "evidence": [ { "database": "UniProtKB", "id": "P49147", "url": "https://www.uniprot.org/uniprotkb/P49147" } ], "pmid": "" }, { "name": "arachidonate metabolic process", "id": "GO:0019369", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019369", "evidence": [ { "database": "UniProtKB", "id": "P49147", "url": "https://www.uniprot.org/uniprotkb/P49147" } ], "pmid": "" }, { "name": "prostaglandin biosynthetic process", "id": "GO:0001516", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001516", "evidence": [ { "database": "UniProtKB", "id": "P49147", "url": "https://www.uniprot.org/uniprotkb/P49147" } ], "pmid": "" }, { "name": "positive regulation of T-helper 1 type immune response", "id": "GO:0002827", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002827", "evidence": [ { "database": "UniProtKB", "id": "P49147", "url": "https://www.uniprot.org/uniprotkb/P49147" } ], "pmid": "" }, { "name": "positive regulation of platelet activation", "id": "GO:0010572", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010572", "evidence": [ { "database": "UniProtKB", "id": "P49147", "url": "https://www.uniprot.org/uniprotkb/P49147" } ], "pmid": "" }, { "name": "monoacylglycerol biosynthetic process", "id": "GO:0006640", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006640", "evidence": [ { "database": "UniProtKB", "id": "P49147", "url": "https://www.uniprot.org/uniprotkb/P49147" } ], "pmid": "" }, { "name": "phosphatidylglycerol catabolic process", "id": "GO:0034478", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034478", "evidence": [ { "database": "UniProtKB", "id": "P49147", "url": "https://www.uniprot.org/uniprotkb/P49147" } ], "pmid": "" }, { "name": "phospholipid catabolic process", "id": "GO:0009395", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009395", "evidence": [ { "database": "UniProtKB", "id": "P49147", "url": "https://www.uniprot.org/uniprotkb/P49147" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 9, "go_terms": [ { "name": "phosphatidylinositol-5-phosphate binding", "id": "GO:0010314", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010314", "evidence": [ { "database": "UniProtKB", "id": "P49147", "url": "https://www.uniprot.org/uniprotkb/P49147" } ], "pmid": "" }, { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "P49147", "url": "https://www.uniprot.org/uniprotkb/P49147" } ], "pmid": "" }, { "name": "phosphatidylcholine lysophospholipase activity", "id": "GO:0004622", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004622", "evidence": [ { "database": "UniProtKB", "id": "P49147", "url": "https://www.uniprot.org/uniprotkb/P49147" } ], "pmid": "" }, { "name": "phospholipase A2 activity", "id": "GO:0004623", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004623", "evidence": [ { "database": "UniProtKB", "id": "P49147", "url": "https://www.uniprot.org/uniprotkb/P49147" } ], "pmid": "" }, { "name": "calcium-dependent phospholipid binding", "id": "GO:0005544", "url": 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The reference sequence was derived from JAENSK010000339.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001103257", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001103257" } ] }, { "annotation": "May participate in signaling pathways.", "evidence": [ { "database": "UniProtKB", "id": "Q02977", "url": "https://www.uniprot.org/uniprotkb/Q02977#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q02977", "url": "https://www.uniprot.org/uniprotkb/Q02977" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "YRK", "url": "https://www.uniprot.org/uniprotkb/Q02977", "locus": {} } ], "crossref": [ { "id": "Q02977", "url": "https://alphafold.ebi.ac.uk/entry/Q02977", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000032199", "url": 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"categories": [ "Protein Classification", "Other" ] }, { "id": "PF00018", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00018", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07714", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07714", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q02977", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q02977", "database": "PRO", "categories": [ "Protein" ] }, { "id": "R-GGA-432142", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-432142", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-6798695", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001103257", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001103257", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "10596", "url": "https://www.rhea-db.org/rhea/10596", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A1D5P353", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P353", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5P353-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P353-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q02977", "url": "https://www.uniprot.org/uniprotkb/Q02977", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q02977-1", "url": "https://www.uniprot.org/uniprotkb/Q02977-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGCVHCKEKISGKGQGGSGTGTPAHPPSQYDPDPTQLSGAFTHIPDFNNFHAAAVSPPVPFSGPGFYPCNTLQAHSSITGGGVTLFIALYDYEARTEDDLSFQKGEKFHIINNTEGDWWEARSLSSGATGYIPSNYVAPVDSIQAEEWYFGKIGRKDAERQLLCHGNCRGTFLIRESETTKGAYSLSIRDWDEAKGDHVKHYKIRKLDSGGYYITTRAQFDTIQQLVQHYIERAAGLCCRLAVPCPKGTPKLADLSVKTKDVWEIPRESLQLLQKLGNGQFGEVWMGTWNGTTKVAVKTLKPGTMSPEAFLEEAQIMKRLRHDKLVQLYAVVSEEPIYIVTEFMSQGSLLDFLKDGDGRYLKLPQLVDMAAQIAAGMAYIERMNYIHRDLRAANILVGDNLVCKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALFGKFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMQCPGGCPPSLHDVMVQCWKREPEERPTFEYLQSFLEDYFTATEPQYQPGDNQ", "length": 536, "header": "sp|Q02977-1|YRK_CHICK Isoform 1 of Proto-oncogene tyrosine-protein kinase Yrk OS=Gallus gallus OX=9031 GN=YRK PE=2 SV=2 CANONICAL=Q02977-1" }, "isoforms": [ { "isoform_ac": "A0A1D5P353-1", "url": "https://www.uniprot.org/uniprotkb/Q02977/entry#A0A1D5P353-1", "sequence": { "sequence": "MGCVHCKEKISGKGQGGSGTGTPAHPPSQYDPDPTQLSGAFTHIPDFNNFHAAAVSPPVPFSGPGFYPCNTLQAHSSITGGGVTLFIALYDYEARTEDDLSFQKGEKFHIINNTEGDWWEARSLSSGATGYIPSNYVAPVDSIQAEEWYFGKIGRKDAERQLLCHGNCRGTFLIRESETTKGAYSLSIRDWDEAKGDHVKHYKIRKLDSGGYYITTRAQFDTIQQLVQHYIECNDGLCHLLTRACPAMKPQTLGLAKDAWEIERESISLDKKLGMGCFGDVWMGTWNGTTKVAVKTLKPGTMSPEAFLEEAQIMKRLRHDKLVQLYAVVSEEPIYIVTEFMSQGSLLDFLKDGDGRYLKLPQLVDMAAQIAAGMAYIERMNYIHRDLRAANILVGDNLVCKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALFGKFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMQCPGGCPPSLHDVMVQCWKREPEERPTFEYLQSFLEDYFTATEPQYQPGDNQ", "length": 533, "header": "tr|A0A1D5P353-1|YRK_CHICK Computationally mapped isoform of Proto-oncogene tyrosine-protein kinase Yrk OS=Gallus gallus OX=9031 GN=YRK PE=2 SV=1 CANONICAL=Q02977-1" }, "locus": { "chromosome": "23", "start_pos": 2424458, "end_pos": 2420301, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040673.1", "url": "https://www.ensembl.org/id/ENSGALT00010040673.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023638.1", "url": "https://www.ensembl.org/id/ENSGALP00010023638.1" } ] } }, { "isoform_ac": "Q02977-1", "url": "https://www.uniprot.org/uniprotkb/Q02977/entry#Q02977-1", "sequence": { "sequence": "MGCVHCKEKISGKGQGGSGTGTPAHPPSQYDPDPTQLSGAFTHIPDFNNFHAAAVSPPVPFSGPGFYPCNTLQAHSSITGGGVTLFIALYDYEARTEDDLSFQKGEKFHIINNTEGDWWEARSLSSGATGYIPSNYVAPVDSIQAEEWYFGKIGRKDAERQLLCHGNCRGTFLIRESETTKGAYSLSIRDWDEAKGDHVKHYKIRKLDSGGYYITTRAQFDTIQQLVQHYIERAAGLCCRLAVPCPKGTPKLADLSVKTKDVWEIPRESLQLLQKLGNGQFGEVWMGTWNGTTKVAVKTLKPGTMSPEAFLEEAQIMKRLRHDKLVQLYAVVSEEPIYIVTEFMSQGSLLDFLKDGDGRYLKLPQLVDMAAQIAAGMAYIERMNYIHRDLRAANILVGDNLVCKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALFGKFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMQCPGGCPPSLHDVMVQCWKREPEERPTFEYLQSFLEDYFTATEPQYQPGDNQ", "length": 536, "header": "sp|Q02977-1|YRK_CHICK Isoform 1 of Proto-oncogene tyrosine-protein kinase Yrk OS=Gallus gallus OX=9031 GN=YRK PE=2 SV=2 CANONICAL=Q02977-1" }, "locus": { "chromosome": "23", "start_pos": 2424458, "end_pos": 2420301, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040679.1", "url": "https://www.ensembl.org/id/ENSGALT00010040679.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023644.1", "url": "https://www.ensembl.org/id/ENSGALP00010023644.1" } ] } } ], "glycosylation": [], "phosphorylation": [ { "start_pos": 419, "end_pos": 419, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine; by autocatalysis", "evidence": [ { "database": "UniProtKB", "id": "Q02977", "url": "https://www.uniprot.org/uniprotkb/Q02977" } ], "site_lbl": "Tyr419" }, { "start_pos": 530, "end_pos": 530, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine", "evidence": [ { "database": "UniProtKB", "id": "Q02977", "url": "https://www.uniprot.org/uniprotkb/Q02977" } ], "site_lbl": "Tyr530" } ], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "A novel Yes-related kinase, Yrk, is expressed at elevated levels in neural and hematopoietic tissues.", "journal": "Oncogene", "date": "1993", "authors": "Sudol M, Greulich H, Newman L, Sarkar A, Sukegawa J, Yamamoto T", "evidence": [ { "database": "UniProtKB", "id": "Q02977", "url": "https://www.uniprot.org/uniprotkb/Q02977" } ], "reference": [ { "type": "PubMed", "id": "8455940", "url": "https://glygen.org/publication/PubMed/8455940" } ] } ], "pathway": [ { "id": "gga:777583", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:777583", "resource": "KEGG Pathway" }, { "id": "R-GGA-432142", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-432142", "resource": "Reactome", "description": "Platelet sensitization by LDL" }, { "id": "R-GGA-6798695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798695", "resource": "Reactome", "description": "Neutrophil degranulation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "phosphotyrosine residue binding", "id": "GO:0001784", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001784", "evidence": [ { "database": "UniProtKB", "id": "Q02977", "url": "https://www.uniprot.org/uniprotkb/Q02977" } ], "pmid": "" }, { "name": "non-membrane spanning protein tyrosine kinase activity", "id": "GO:0004715", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004715", "evidence": [ { "database": "UniProtKB", "id": "Q02977", "url": "https://www.uniprot.org/uniprotkb/Q02977" } ], "pmid": "" }, { "name": "signaling receptor binding", "id": "GO:0005102", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005102", "evidence": [ { "database": "UniProtKB", "id": "Q02977", "url": "https://www.uniprot.org/uniprotkb/Q02977" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q02977", "url": "https://www.uniprot.org/uniprotkb/Q02977" } ], "pmid": "" }, { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "Q02977", "url": "https://www.uniprot.org/uniprotkb/Q02977" } ], "pmid": "" }, { "name": "Fc-gamma receptor I complex binding", "id": "GO:0034988", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034988", "evidence": [ { "database": "UniProtKB", "id": "Q02977", "url": "https://www.uniprot.org/uniprotkb/Q02977" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q02977", "url": "https://www.uniprot.org/uniprotkb/Q02977" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q02977", "url": "https://www.uniprot.org/uniprotkb/Q02977" } ], "pmid": "" }, { "name": "actin cytoskeleton", "id": "GO:0015629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015629", "evidence": [ { "database": "UniProtKB", "id": "Q02977", "url": "https://www.uniprot.org/uniprotkb/Q02977" } ], "pmid": "" }, { "name": "ruffle membrane", "id": "GO:0032587", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032587", "evidence": [ { "database": "UniProtKB", "id": "Q02977", "url": "https://www.uniprot.org/uniprotkb/Q02977" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 12, "go_terms": [ { "name": "cell surface receptor protein tyrosine kinase signaling pathway", "id": "GO:0007169", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007169", "evidence": [ { "database": "UniProtKB", "id": "Q02977", "url": "https://www.uniprot.org/uniprotkb/Q02977" } ], "pmid": "" }, { "name": "integrin-mediated signaling pathway", "id": "GO:0007229", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007229", "evidence": [ { "database": "UniProtKB", "id": "Q02977", "url": "https://www.uniprot.org/uniprotkb/Q02977" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "Q02977", "url": "https://www.uniprot.org/uniprotkb/Q02977" } ], "pmid": "" }, { "name": "positive regulation of cell migration", "id": "GO:0030335", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030335", "evidence": [ { "database": "UniProtKB", "id": "Q02977", "url": "https://www.uniprot.org/uniprotkb/Q02977" } ], "pmid": "" }, { "name": "defense response to Gram-positive bacterium", "id": "GO:0050830", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050830", "evidence": [ { "database": "UniProtKB", "id": "Q02977", "url": "https://www.uniprot.org/uniprotkb/Q02977" } ], "pmid": "" }, { "name": "positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction", "id": "GO:0051897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051897", "evidence": [ { "database": "UniProtKB", "id": "Q02977", "url": "https://www.uniprot.org/uniprotkb/Q02977" } ], "pmid": "" }, { "name": "positive regulation of mast cell degranulation", "id": "GO:0043306", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043306", "evidence": [ { "database": "UniProtKB", "id": "Q02977", "url": "https://www.uniprot.org/uniprotkb/Q02977" } ], "pmid": "" }, { "name": "positive regulation of cytokine production", "id": "GO:0001819", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001819", "evidence": [ { "database": "UniProtKB", "id": "Q02977", "url": "https://www.uniprot.org/uniprotkb/Q02977" } ], "pmid": "" }, { "name": "regulation of cell shape", "id": "GO:0008360", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008360", "evidence": [ { "database": "UniProtKB", "id": "Q02977", "url": "https://www.uniprot.org/uniprotkb/Q02977" } ], "pmid": "" }, { "name": "regulation of innate immune response", "id": "GO:0045088", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045088", "evidence": [ { "database": "UniProtKB", "id": "Q02977", "url": "https://www.uniprot.org/uniprotkb/Q02977" } ], "pmid": "" }, { "name": "regulation of phagocytosis", "id": "GO:0050764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050764", "evidence": [ { "database": "UniProtKB", "id": "Q02977", "url": "https://www.uniprot.org/uniprotkb/Q02977" } ], "pmid": "" }, { "name": "negative regulation of natural killer cell activation", "id": "GO:0032815", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032815", "evidence": [ { "database": "UniProtKB", "id": "Q02977", "url": "https://www.uniprot.org/uniprotkb/Q02977" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 112, "end_pos": 114, "annotation": "n_glycosylation_sequon" }, { "start_pos": 290, "end_pos": 292, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "10596", "name": "", "equation": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V1ADF0-1", "F1N9Y5-1", "A0A8V0XQG0-1", "A0A8V0Y9A0-1", "A0A8V1AFM7-1", "A0A8V0Z0R8-1", "A0A8V0Z4B2-1", "A0A8V0ZBN6-1", "P09324-1", "A0A8V0XHW1-1", "A0A8V0YW12-1", "A0A8V0YUJ4-1", "A0A8V0ZSN8-1", "F1NVF2-1", "A0A8V1AKW4-1", "A0A8V0XB17-1", "A0A8V0ZC34-1", "A0A8V0YYC1-1", "A0A8V0ZND5-1", "A0A8V1ACF7-1", "A0A8V0ZP30-1", "E1BTE1-1", "Q07497-1", "A0A8V0X6E7-1", "F1NCL8-1", "A0A8V0XNF4-1", "A0A8V0XN86-1", "A0A8V0YEV0-1", "A0A8V0XQ80-1", "A0A8V0XZ82-1", "A0A8V0YZE5-1", "A0A8V0YYZ7-1", "A0A8V0YCV8-1", "A0A8V0YGR1-1", "A0A8V0YNY4-1", "A0A8V0YXM5-1", "A0A8V0YXZ9-1", "A0A3Q2UKD3-1", "A0A8V0YIT6-1", "A0A8V0YIV6-1", "R4GJW5-1", "A0A8V1A3N1-1", "A0A8V1A9R2-1", "A0A8V0ZE65-1", "A0A8V0ZER1-1", "A0A8V0ZXS7-1", "A0A8V1A7N1-1", "H9KZZ1-1", "F1NQL9-1", "A0A8V1ABP4-1", "F1NZY8-1", "Q02977-1", "A0A1D5PD64-1", "A0A8V0ZDU6-1", "A0A3Q2U1T2-1", "R4GJB8-1", "A0A3Q2U639-1", "A0A8V0X5W9-1", "E1C7Z1-1", "A0A8V0Y7Y3-1", "Q5ZIU3-1", "A0A8V0YPR4-1", "A0A8V0YT43-1", "A0A8V0Z3S3-1", "A0A8V0YJJ1-1", "A0A8V0YKP8-1", "A0A8V0YZ74-1", "A0A8V0ZWV8-1", "A0A8V1A069-1", "A0A8V1A7E0-1", "A0A8V1AEL3-1", "E1BTT3-1", "F1N996-1", "H9KZZ2-1", "E1C2C8-1", "Q05876-1", "Q90891-1", "O42422-1", "P00523-1", "P08941-1", "P13387-1", "P18460-1", "P18461-1", "P21804-1", "P28693-1", "P29318-1", "P42683-1", "P54755-1", "Q00944-1", "Q07494-1", "Q07496-1", "Q07498-1", "Q08156-1", "Q6XUX0-1", "Q75R65-1", "Q8AXY6-1", "Q8JH64-1", "Q8QHL3-1", "Q91009-1", "Q91044-1", "Q91987-1", "Q98949-1", "Q9PUF6-1", "F1NW21-1", "A0A8V0YLC3-1", "A0A8V0Z7L6-1", "F1NJX6-1", "A0A8V0YUC4-1", "F1NUX4-1", "A0A8V1A2E6-1", "E1BX69-1", "A0A8V0XPF0-1", "A0A8V0XFC9-1", "A0A8V0XBZ6-1", "A0A8V0ZRU7-1", "A0A8V0ZXD3-1", "A0A8V0YYI3-1", "A0A8V0YWW2-1", "A0A8V0YZP9-1", "A0A8V0YRJ8-1", "F1NLR7-1", "A0A8V0XCY6-1", "A0A8V1AMK9-1", "A0A8V0Z189-1", "P41239-1" ], "evidence": [ { "id": "10596", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/10596" } ] }, { "id": "R-GGA-432129", "name": "FGR binds and phosphorylates LRP8", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q02977-1" ], "evidence": [ { "id": "R-GGA-432129", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-432129" } ] }, { "id": "R-GGA-432148", "name": "Fgr may phosphorylate p38 MAPK", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A1D5PIQ5-1", "Q02977-1" ], "evidence": [ { "id": "R-GGA-432148", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-432148" } ] }, { "id": "R-GGA-6798748", "name": "Exocytosis of secretory granule lumen proteins", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "extracellular region, secretory granule lumen", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A1D5PAA8-1", "A0A8V0X7U8-1", "A0A1D5PLH7-1", "A0A8V0XGV3-1", "A0A8V0XQ57-1", "A0A8V1AAF2-1", "A0A8V1ADZ5-1", "A0A8V1AIR0-1", "O57535-1", "Q90835-1", "A0A8V0ZIP8-1", "A0A8V0ZPK4-1", "A0A8V0ZQ64-1", "A0A8V0ZR27-1", "A0A8V0ZWJ4-1", "A0A8V0YHC8-1", "A0A8V0ZFP5-1", "A0A8V0ZG96-1", "A0A8V0ZTG8-1", "A0A8V0ZVL2-1", "A0A8V0Z0N7-1", "A0A8V0Z3A2-1", "F1NG97-1", "A0A8V0ZAK2-1", "A0A8V0ZG12-1", "A0A1D5PIQ5-1", "Q02977-1", "A0A8V0XXA9-1", "A0A8V0YAA4-1", "A0A8V0Y5M6-1", "A0A8V0YBU4-1", "A0A8V0YHT7-1" ], "evidence": [ { "id": "R-GGA-6798748", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798748" } ] }, { "id": "R-GGA-8948034", "name": "FGR binds LDL:LRP8", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q02977-1" ], "evidence": [ { "id": "R-GGA-8948034", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8948034" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5PAA8", "gene_name": "GYG1", "activity": [ { "ec_number": "2.4.1.186", "activity": "[1,4-alpha-D-glucosyl](n)-L-tyrosyl-[glycogenin] + UDP-alpha-D-glucose = [1,4-alpha-D-glucosyl](n+1)-L-tyrosyl-[glycogenin] + UDP + H(+).", "evidence": [ { "id": "A0A1D5PAA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PAA8" } ] }, { "ec_number": "2.4.1.186", "activity": "", "evidence": [ { "id": "A0A1D5PAA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PAA8" } ] } ] }, { "uniprot_ac": "A0A1D5PD64", "gene_name": "MAP2K3", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PD64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PD64" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A1D5PD64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PD64" } ] } ] }, { "uniprot_ac": "A0A1D5PIQ5", "gene_name": "MAPK14", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PIQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PIQ5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A1D5PIQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PIQ5" } ] } ] }, { "uniprot_ac": "A0A1D5PLH7", "gene_name": "PRDX4", "activity": [ { "ec_number": "1.11.1.24", "activity": "a hydroperoxide + [thioredoxin]-dithiol = an alcohol + [thioredoxin]-disulfide + H2O.", "evidence": [ { "id": "A0A1D5PLH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLH7" } ] }, { "ec_number": "1.11.1.24", "activity": "", "evidence": [ { "id": "A0A1D5PLH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLH7" } ] } ] }, { "uniprot_ac": "A0A3Q2U1T2", "gene_name": "BLK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2U1T2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U1T2" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A3Q2U1T2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U1T2" } ] } ] }, { "uniprot_ac": "A0A3Q2U639", "gene_name": "FYN", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2U639", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U639" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A3Q2U639", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U639" } ] } ] }, { "uniprot_ac": "A0A3Q2UKD3", "gene_name": "TEK", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2UKD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UKD3" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A3Q2UKD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UKD3" } ] } ] }, { "uniprot_ac": "A0A8V0X5W9", "gene_name": "TYK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X5W9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X5W9" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0X5W9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X5W9" } ] } ] }, { "uniprot_ac": "A0A8V0X6E7", "gene_name": "FES", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X6E7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X6E7" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0X6E7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X6E7" } ] } ] }, { "uniprot_ac": "A0A8V0X7U8", "gene_name": "ALDOA", "activity": [ { "ec_number": "4.1.2.13", "activity": "beta-D-fructose 1,6-bisphosphate = D-glyceraldehyde 3-phosphate + dihydroxyacetone phosphate.", "evidence": [ { "id": "A0A8V0X7U8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X7U8" } ] }, { "ec_number": "4.1.2.13", "activity": "", "evidence": [ { "id": "A0A8V0X7U8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X7U8" } ] } ] }, { "uniprot_ac": "A0A8V0XB17", "gene_name": "FGFR2", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XB17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XB17" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0XB17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XB17" } ] } ] }, { "uniprot_ac": "A0A8V0XBZ6", "gene_name": "EPHA7", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XBZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XBZ6" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0XBZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XBZ6" } ] } ] }, { "uniprot_ac": "A0A8V0XCY6", "gene_name": "TTK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XCY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCY6" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V0XCY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCY6" } ] } ] }, { "uniprot_ac": "A0A8V0XFC9", "gene_name": "EPHA5", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XFC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFC9" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0XFC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFC9" } ] } ] }, { "uniprot_ac": "A0A8V0XGV3", "gene_name": "DDX3X", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XGV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XGV3" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0XGV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XGV3" } ] } ] }, { "uniprot_ac": "A0A8V0XHW1", "gene_name": "LYN", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XHW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XHW1" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0XHW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XHW1" } ] } ] }, { "uniprot_ac": "A0A8V0XN86", "gene_name": "MUSK", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XN86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XN86" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0XN86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XN86" } ] } ] }, { "uniprot_ac": "A0A8V0XNF4", "gene_name": "EGFR", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XNF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNF4" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0XNF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNF4" } ] } ] }, { "uniprot_ac": "A0A8V0XPF0", "gene_name": "EPHA6", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XPF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XPF0" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0XPF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XPF0" } ] } ] }, { "uniprot_ac": "A0A8V0XQ57", "gene_name": "APRT", "activity": [ { "ec_number": "2.4.2.7", "activity": "AMP + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + adenine.", "evidence": [ { "id": "A0A8V0XQ57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ57" } ] }, { "ec_number": "2.4.2.7", "activity": "", "evidence": [ { "id": "A0A8V0XQ57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ57" } ] } ] }, { "uniprot_ac": "A0A8V0XQ80", "gene_name": "FLT3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQ80", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ80" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0XQ80", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ80" } ] } ] }, { "uniprot_ac": "A0A8V0XQG0", "gene_name": "FLT1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQG0" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0XQG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQG0" } ] } ] }, { "uniprot_ac": "A0A8V0XXA9", "gene_name": "GPI", "activity": [ { "ec_number": "5.3.1.9", "activity": "alpha-D-fructose 6-phosphate = beta-D-fructose 6-phosphate.", "evidence": [ { "id": "A0A8V0XXA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXA9" } ] }, { "ec_number": "5.3.1.9", "activity": "", "evidence": [ { "id": "A0A8V0XXA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXA9" } ] } ] }, { "uniprot_ac": "A0A8V0XZ82", "gene_name": "PTK2B", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XZ82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XZ82" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0XZ82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XZ82" } ] } ] }, { "uniprot_ac": "A0A8V0Y5M6", "gene_name": "HK3", "activity": [ { "ec_number": "2.7.1.1", "activity": "D-fructose + ATP = D-fructose 6-phosphate + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y5M6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5M6" } ] }, { "ec_number": "2.7.1.1", "activity": "", "evidence": [ { "id": "A0A8V0Y5M6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5M6" } ] } ] }, { "uniprot_ac": "A0A8V0Y7Y3", "gene_name": "ABL2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y7Y3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7Y3" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0Y7Y3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7Y3" } ] } ] }, { "uniprot_ac": "A0A8V0Y9A0", "gene_name": "PTK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y9A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9A0" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0Y9A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9A0" } ] } ] }, { "uniprot_ac": "A0A8V0YAA4", "gene_name": "XRCC6", "activity": [ { "ec_number": "4.2.99.18", "activity": "2'-deoxyribonucleotide-(2'-deoxyribose 5'-phosphate)-2'-deoxyribonucleotide-DNA = a 3'-end 2'-deoxyribonucleotide-(2,3-dehydro-2,3-deoxyribose 5'-phosphate)-DNA + a 5'-end 5'-phospho-2'-deoxyribonucleoside-DNA + H(+).", "evidence": [ { "id": "A0A8V0YAA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAA4" } ] }, { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YAA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAA4" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A8V0YAA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAA4" } ] }, { "ec_number": "4.2.99.18", "activity": "", "evidence": [ { "id": "A0A8V0YAA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAA4" } ] } ] }, { "uniprot_ac": "A0A8V0YBU4", "gene_name": "PDXK", "activity": [ { "ec_number": "2.7.1.35", "activity": "pyridoxine + ATP = pyridoxine 5'-phosphate + ADP + H(+).", "evidence": [ { "id": "A0A8V0YBU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBU4" } ] }, { "ec_number": "2.7.1.35", "activity": "", "evidence": [ { "id": "A0A8V0YBU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBU4" } ] } ] }, { "uniprot_ac": "A0A8V0YCV8", "gene_name": "NTRK2", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YCV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCV8" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0YCV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCV8" } ] } ] }, { "uniprot_ac": "A0A8V0YEV0", "gene_name": "WEE2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YEV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEV0" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0YEV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEV0" } ] } ] }, { "uniprot_ac": "A0A8V0YGR1", "gene_name": "RET", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YGR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGR1" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0YGR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGR1" } ] } ] }, { "uniprot_ac": "A0A8V0YHC8", "gene_name": "VCP", "activity": [ { "ec_number": "3.6.4.6", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YHC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHC8" } ] }, { "ec_number": "3.6.4.6", "activity": "", "evidence": [ { "id": "A0A8V0YHC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHC8" } ] } ] }, { "uniprot_ac": "A0A8V0YHT7", "gene_name": "DERA", "activity": [ { "ec_number": "4.1.2.4", "activity": "2-deoxy-D-ribose 5-phosphate = D-glyceraldehyde 3-phosphate + acetaldehyde.", "evidence": [ { "id": "A0A8V0YHT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHT7" } ] }, { "ec_number": "4.1.2.4", "activity": "", "evidence": [ { "id": "A0A8V0YHT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHT7" } ] } ] }, { "uniprot_ac": "A0A8V0YIT6", "gene_name": "ERBB4", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YIT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIT6" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0YIT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIT6" } ] } ] }, { "uniprot_ac": "A0A8V0YIV6", "gene_name": "DYRK1A", "activity": [ { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] } ] }, { "uniprot_ac": "A0A8V0YJJ1", "gene_name": "ITK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YJJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJJ1" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0YJJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJJ1" } ] } ] }, { "uniprot_ac": "A0A8V0YKP8", "gene_name": "VEGFRKDRL", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YKP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKP8" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0YKP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKP8" } ] } ] }, { "uniprot_ac": "A0A8V0YLC3", "gene_name": "PDGFRA", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YLC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLC3" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0YLC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLC3" } ] } ] }, { "uniprot_ac": "A0A8V0YNY4", "gene_name": "JAK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": 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"https://www.uniprot.org/uniprotkb/A0A8V0YRJ8" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0YRJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRJ8" } ] } ] }, { "uniprot_ac": "A0A8V0YT43", "gene_name": "HCK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YT43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YT43" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0YT43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YT43" } ] } ] }, { "uniprot_ac": "A0A8V0YUC4", "gene_name": "EPHB3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YUC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUC4" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0YUC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUC4" } ] } ] }, { "uniprot_ac": "A0A8V0YUJ4", "gene_name": "BTK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YUJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUJ4" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0YUJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUJ4" } ] } ] }, { "uniprot_ac": "A0A8V0YW12", "gene_name": "FRK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YW12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YW12" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": 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"uniprot_ac": "A0A8V0YYI3", "gene_name": "EPHA8", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YYI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYI3" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0YYI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYI3" } ] } ] }, { "uniprot_ac": "A0A8V0YYZ7", "gene_name": "FGFR3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YYZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYZ7" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0YYZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYZ7" } ] } ] }, { "uniprot_ac": "A0A8V0YZ74", "gene_name": "MAP2K5", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZ74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZ74" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V0YZ74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZ74" } ] } ] }, { "uniprot_ac": "A0A8V0YZE5", "gene_name": "PDGFRB", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZE5" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0YZE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZE5" } ] } ] }, { "uniprot_ac": "A0A8V0YZP9", "gene_name": "EPHB2", "activity": [ { "ec_number": "2.7.10.1", "activity": 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+ ADP + H(+).", "evidence": [ { "id": "A0A8V0Z0R8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0R8" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0Z0R8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0R8" } ] } ] }, { "uniprot_ac": "A0A8V0Z189", "gene_name": "PKDCCA", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z189", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z189" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0Z189", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z189" } ] } ] }, { "uniprot_ac": "A0A8V0Z3A2", "gene_name": "PPIE", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "A0A8V0Z3A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3A2" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "A0A8V0Z3A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3A2" } ] } ] }, { "uniprot_ac": "A0A8V0Z3S3", "gene_name": "ALK", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z3S3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3S3" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0Z3S3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3S3" } ] } ] }, { "uniprot_ac": "A0A8V0Z4B2", "gene_name": "MERTK", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z4B2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4B2" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0Z4B2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4B2" } ] } ] }, { "uniprot_ac": "A0A8V0Z7L6", "gene_name": "FGFR1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z7L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7L6" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0Z7L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7L6" } ] } ] }, { "uniprot_ac": "A0A8V0ZAK2", "gene_name": "PYGL", "activity": [ { "ec_number": "2.4.1.1", "activity": "[(1->4)-alpha-D-glucosyl](n) + phosphate = [(1->4)-alpha-D-glucosyl](n-1) + alpha-D-glucose 1-phosphate.", "evidence": [ { "id": "A0A8V0ZAK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAK2" } ] }, { "ec_number": "2.4.1.1", "activity": "", "evidence": [ { "id": "A0A8V0ZAK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAK2" } ] } ] }, { "uniprot_ac": "A0A8V0ZBN6", "gene_name": "MAP2K1", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZBN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBN6" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V0ZBN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBN6" } ] } ] }, { "uniprot_ac": "A0A8V0ZC34", "gene_name": "AXL", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZC34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC34" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0ZC34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC34" } ] } ] }, { "uniprot_ac": "A0A8V0ZDU6", "gene_name": "SRC", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZDU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDU6" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0ZDU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDU6" } ] } ] }, { "uniprot_ac": "A0A8V0ZE65", "gene_name": "NTRK3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZE65", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE65" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0ZE65", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE65" } ] } ] }, { "uniprot_ac": "A0A8V0ZER1", "gene_name": "IGF1R", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZER1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZER1" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0ZER1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZER1" } ] } ] }, { "uniprot_ac": "A0A8V0ZFP5", "gene_name": "PGAM1", "activity": [ { "ec_number": "5.4.2.11", "activity": "(2R)-2-phosphoglycerate = (2R)-3-phosphoglycerate.", "evidence": [ { "id": "A0A8V0ZFP5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFP5" } ] }, { "ec_number": "5.4.2.4", "activity": "(2R)-3-phospho-glyceroyl phosphate = (2R)-2,3-bisphosphoglycerate + H(+).", "evidence": [ { "id": 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phosphoenolpyruvate + H(+).", "evidence": [ { "id": "A0A8V0ZG96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG96" } ] }, { "ec_number": "2.7.1.40", "activity": "", "evidence": [ { "id": "A0A8V0ZG96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG96" } ] } ] }, { "uniprot_ac": "A0A8V0ZIP8", "gene_name": "XRCC5", "activity": [ { "ec_number": "4.2.99.18", "activity": "2'-deoxyribonucleotide-(2'-deoxyribose 5'-phosphate)-2'-deoxyribonucleotide-DNA = a 3'-end 2'-deoxyribonucleotide-(2,3-dehydro-2,3-deoxyribose 5'-phosphate)-DNA + a 5'-end 5'-phospho-2'-deoxyribonucleoside-DNA + H(+).", "evidence": [ { "id": "A0A8V0ZIP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIP8" } ] }, { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZIP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIP8" } ] }, { "ec_number": "4.2.99.18", "activity": "", "evidence": [ { "id": "A0A8V0ZIP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIP8" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A8V0ZIP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIP8" } ] } ] }, { "uniprot_ac": "A0A8V0ZND5", "gene_name": "CSK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZND5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZND5" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0ZND5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZND5" } ] } ] }, { "uniprot_ac": "A0A8V0ZP30", "gene_name": "LTK", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZP30", "database": 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"url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ64" } ] }, { "ec_number": "3.2.1.33", "activity": "Hydrolysis of (1->6)-alpha-D-glucosidic branch linkages in glycogen phosphorylase limit dextrin.", "evidence": [ { "id": "A0A8V0ZQ64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ64" } ] }, { "ec_number": "2.4.1.25", "activity": "", "evidence": [ { "id": "A0A8V0ZQ64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ64" } ] }, { "ec_number": "3.2.1.33", "activity": "", "evidence": [ { "id": "A0A8V0ZQ64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ64" } ] } ] }, { "uniprot_ac": "A0A8V0ZR27", "gene_name": "PAFAH1B2", "activity": [ { "ec_number": "3.1.1.47", "activity": "a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + acetate + H(+).", "evidence": [ { "id": "A0A8V0ZR27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR27" } ] }, { "ec_number": "3.1.1.47", "activity": "", "evidence": [ { "id": "A0A8V0ZR27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR27" } ] } ] }, { "uniprot_ac": "A0A8V0ZRU7", "gene_name": "EPHB6", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZRU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRU7" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0ZRU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRU7" } ] } ] }, { "uniprot_ac": "A0A8V0ZSN8", "gene_name": "JAK1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZSN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSN8" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0ZSN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSN8" } ] } ] }, { "uniprot_ac": "A0A8V0ZTG8", "gene_name": "PFKL", "activity": [ { "ec_number": "2.7.1.11", "activity": "beta-D-fructose 6-phosphate + ATP = beta-D-fructose 1,6-bisphosphate + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZTG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTG8" } ] }, { "ec_number": "2.7.1.11", "activity": "", "evidence": [ { "id": "A0A8V0ZTG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTG8" } ] } ] }, { "uniprot_ac": "A0A8V0ZVL2", "gene_name": "CAT", "activity": [ { "ec_number": "1.11.1.6", "activity": "2 H2O2 = O2 + 2 H2O.", "evidence": [ { "id": "A0A8V0ZVL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVL2" } ] }, { "ec_number": "1.11.1.6", "activity": "", "evidence": [ { "id": "A0A8V0ZVL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVL2" } ] } ] }, { "uniprot_ac": "A0A8V0ZWJ4", "gene_name": "ALOX5", "activity": [ { "ec_number": "1.13.11.34", "activity": "(5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 = leukotriene A4 + H2O.", "evidence": [ { "id": "A0A8V0ZWJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWJ4" } ] }, { "ec_number": "1.13.11.34", "activity": "", "evidence": [ { "id": "A0A8V0ZWJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWJ4" } ] } ] }, { "uniprot_ac": "A0A8V0ZWV8", "gene_name": "TIE1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZWV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWV8" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0ZWV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWV8" } ] } ] }, { "uniprot_ac": "A0A8V0ZXD3", "gene_name": "EPHA4", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZXD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXD3" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0ZXD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXD3" } ] } ] }, { "uniprot_ac": "A0A8V0ZXS7", "gene_name": "ERBB2", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZXS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXS7" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0ZXS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXS7" } ] } ] }, { "uniprot_ac": "A0A8V1A069", "gene_name": "TESK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A069", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A069" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1A069", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A069" } ] } ] }, { "uniprot_ac": "A0A8V1A2E6", "gene_name": "EPHB1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A2E6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2E6" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V1A2E6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2E6" } ] } ] }, { "uniprot_ac": "A0A8V1A3N1", "gene_name": "MST1R", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A3N1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3N1" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V1A3N1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3N1" } ] } ] }, { "uniprot_ac": "A0A8V1A7E0", "gene_name": "DYRK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1A7E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E0" } ] } ] }, { "uniprot_ac": "A0A8V1A7N1", "gene_name": "ERBB3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7N1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7N1" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V1A7N1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7N1" } ] } ] }, { "uniprot_ac": "A0A8V1A9R2", "gene_name": "JAK3", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A9R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9R2" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V1A9R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9R2" } ] } ] }, { "uniprot_ac": "A0A8V1AAF2", "gene_name": "MIF", "activity": [ { "ec_number": "5.3.2.1", "activity": "3-phenylpyruvate = enol-phenylpyruvate.", "evidence": [ { "id": "A0A8V1AAF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAF2" } ] }, { "ec_number": "5.3.3.12", "activity": "L-dopachrome = 5,6-dihydroxyindole-2-carboxylate.", "evidence": [ { "id": "A0A8V1AAF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAF2" } ] }, { "ec_number": "5.3.3.12", "activity": "", "evidence": [ { "id": "A0A8V1AAF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAF2" } ] }, { "ec_number": "5.3.2.1", "activity": "", "evidence": [ { "id": "A0A8V1AAF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAF2" } ] } ] }, { "uniprot_ac": "A0A8V1ABP4", "gene_name": "DSTYK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP4" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1ABP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP4" } ] } ] }, { "uniprot_ac": "A0A8V1ACF7", "gene_name": "ABL1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF7" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V1ACF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF7" } ] } ] }, { "uniprot_ac": "A0A8V1ADF0", "gene_name": "MAP2K2", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF0" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V1ADF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF0" } ] } ] }, { "uniprot_ac": "A0A8V1ADZ5", "gene_name": "HDHD3", "activity": [ { "ec_number": "4.2.1.24", "activity": "2 5-aminolevulinate = porphobilinogen + 2 H2O + H(+).", "evidence": [ { "id": "A0A8V1ADZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADZ5" } ] }, { "ec_number": "4.2.1.24", "activity": "", "evidence": [ { "id": "A0A8V1ADZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADZ5" } ] } ] }, { "uniprot_ac": "A0A8V1AEL3", "gene_name": "ZAP70", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AEL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEL3" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V1AEL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEL3" } ] } ] }, { "uniprot_ac": "A0A8V1AFM7", "gene_name": "INSR", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AFM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFM7" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V1AFM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFM7" } ] } ] }, { "uniprot_ac": "A0A8V1AIR0", "gene_name": "ALDOC", "activity": [ { "ec_number": "4.1.2.13", "activity": "beta-D-fructose 1,6-bisphosphate = D-glyceraldehyde 3-phosphate + dihydroxyacetone phosphate.", "evidence": [ { "id": "A0A8V1AIR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIR0" } ] }, { "ec_number": "4.1.2.13", "activity": "", "evidence": [ { "id": "A0A8V1AIR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIR0" } ] } ] }, { "uniprot_ac": "A0A8V1AKW4", "gene_name": "MAP2K4", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AKW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKW4" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V1AKW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKW4" } ] } ] }, { "uniprot_ac": "A0A8V1AMK9", "gene_name": "BAZ1B", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AMK9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK9" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V1AMK9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK9" } ] } ] }, { "uniprot_ac": "E1BTE1", "gene_name": "WEE2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BTE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BTE1" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "E1BTE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BTE1" } ] } ] }, { "uniprot_ac": "E1BTT3", "gene_name": "BMX", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BTT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BTT3" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "E1BTT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BTT3" } ] } ] }, { "uniprot_ac": "E1BX69", "gene_name": "EIF2AK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BX69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BX69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BX69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BX69" } ] } ] }, { "uniprot_ac": "E1C2C8", "gene_name": "MATK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C2C8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2C8" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "E1C2C8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2C8" } ] } ] }, { "uniprot_ac": "E1C7Z1", "gene_name": "FER", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C7Z1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C7Z1" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "E1C7Z1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C7Z1" } ] } ] }, { "uniprot_ac": "F1N996", "gene_name": "PTK6", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N996", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N996" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F1N996", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N996" } ] } ] }, { "uniprot_ac": "F1N9Y5", "gene_name": "SYK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N9Y5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N9Y5" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F1N9Y5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N9Y5" } ] } ] }, { "uniprot_ac": "F1NCL8", "gene_name": "FGFR4", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NCL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCL8" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1NCL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCL8" } ] } ] }, { "uniprot_ac": "F1NG97", "gene_name": "AMPD3", "activity": [ { "ec_number": "3.5.4.6", "activity": "AMP + H2O + H(+) = IMP + NH4(+).", "evidence": [ { "id": "F1NG97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NG97" } ] }, { "ec_number": "3.5.4.6", "activity": "", "evidence": [ { "id": "F1NG97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NG97" } ] } ] }, { "uniprot_ac": "F1NJX6", "gene_name": "EPHA3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NJX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJX6" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1NJX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJX6" } ] } ] }, { "uniprot_ac": "F1NLR7", "gene_name": "CLK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NLR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLR7" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "F1NLR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLR7" } ] } ] }, { "uniprot_ac": "F1NQL9", "gene_name": "ROS1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NQL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NQL9" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1NQL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NQL9" } ] } ] }, { "uniprot_ac": "F1NUX4", "gene_name": "MTOR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NUX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NUX4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NUX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NUX4" } ] } ] }, { "uniprot_ac": "F1NVF2", "gene_name": "MAP2K6", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NVF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVF2" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "F1NVF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVF2" } ] } ] }, { "uniprot_ac": "F1NW21", "gene_name": "KDR", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NW21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NW21" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1NW21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NW21" } ] } ] }, { "uniprot_ac": "F1NZY8", "gene_name": "TEC", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NZY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NZY8" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F1NZY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NZY8" } ] } ] }, { "uniprot_ac": "H9KZZ1", "gene_name": "NTRK1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "H9KZZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H9KZZ1" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "H9KZZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H9KZZ1" } ] } ] }, { "uniprot_ac": "H9KZZ2", "gene_name": "INSRR", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "H9KZZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H9KZZ2" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "H9KZZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H9KZZ2" } ] } ] }, { "uniprot_ac": "O42422", "gene_name": "EPHA7", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "O42422", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O42422" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "O42422", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O42422" } ] } ] }, { "uniprot_ac": "O57535", "gene_name": "", "activity": [ { "ec_number": "2.7.4.6", "activity": "UDP + ATP = UTP + ADP.", "evidence": [ { "id": "O57535", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O57535" } ] }, { "ec_number": "2.7.4.6", "activity": "", "evidence": [ { "id": "O57535", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O57535" } ] } ] }, { "uniprot_ac": "P00523", "gene_name": "SRC", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "P00523", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00523" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "P00523", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00523" } ] } ] }, { "uniprot_ac": "P08941", "gene_name": "ROS1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "P08941", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P08941" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "P08941", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P08941" } ] } ] }, { "uniprot_ac": "P09324", "gene_name": "YES1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "P09324", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P09324" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "P09324", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P09324" } ] } ] }, { "uniprot_ac": "P13387", "gene_name": "EGFR", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "P13387", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13387" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "P13387", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13387" } ] } ] }, { "uniprot_ac": "P18460", "gene_name": "FGFR3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "P18460", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18460" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "P18460", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18460" } ] } ] }, { "uniprot_ac": "P18461", "gene_name": "FGFR2", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "P18461", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18461" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "P18461", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18461" } ] } ] }, { "uniprot_ac": "P21804", "gene_name": "FGFR1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "P21804", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21804" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "P21804", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21804" } ] } ] }, { "uniprot_ac": "P28693", "gene_name": "EPHB2", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "P28693", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P28693" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "P28693", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P28693" } ] } ] }, { "uniprot_ac": "P29318", "gene_name": "EPHA3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "P29318", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P29318" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "P29318", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P29318" } ] } ] }, { "uniprot_ac": "P41239", "gene_name": "CSK", "activity": [ { "ec_number": "2.7.10.4", "activity": "ATP + [a protein]-(L-tyrosine) = ADP + [a protein]-(L-tyrosine)-phosphate. The optimal peptide substrate contains the sequence (relative to the phosphorylated tyrosine): Glu-Glu-Asp/Glu-Ile-Tyr-Phe-Phe-Phe-Phe. Physiological substrates are C-terminal tail of Src-family protein kinases.", "evidence": [ { "id": "P41239", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P41239" } ] }, { "ec_number": "2.7.10.4", "activity": "", "evidence": [ { "id": "P41239", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P41239" } ] } ] }, { "uniprot_ac": "P42683", "gene_name": "LCK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "P42683", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P42683" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "P42683", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P42683" } ] } ] }, { "uniprot_ac": "P54755", "gene_name": "EPHA5", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "P54755", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P54755" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "P54755", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P54755" } ] } ] }, { "uniprot_ac": "Q00944", "gene_name": "PTK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q00944", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q00944" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "Q00944", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q00944" } ] } ] }, { "uniprot_ac": "Q02977", "gene_name": "YRK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q02977", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q02977" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "Q02977", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q02977" } ] } ] }, { "uniprot_ac": "Q05876", "gene_name": "FYN", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q05876", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q05876" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "Q05876", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q05876" } ] } ] }, { "uniprot_ac": "Q07494", "gene_name": "EPHB1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q07494", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q07494" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "Q07494", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q07494" } ] } ] }, { "uniprot_ac": "Q07496", "gene_name": "EPHA4", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q07496", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q07496" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "Q07496", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q07496" } ] } ] }, { "uniprot_ac": "Q07497", "gene_name": "EPHB5", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q07497", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q07497" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "Q07497", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q07497" } ] } ] }, { "uniprot_ac": "Q07498", "gene_name": "EPHB3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q07498", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q07498" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "Q07498", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q07498" } ] } ] }, { "uniprot_ac": "Q08156", "gene_name": "KIT", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q08156", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08156" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "Q08156", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08156" } ] } ] }, { "uniprot_ac": "Q5ZIU3", "gene_name": "DYRK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + 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"authors" ] } ] }, { "uniprot_canonical_ac": "A0A1D5P3N0-1", "uniprot_ac": "A0A1D5P3N0", "uniprot_id": "A0A1D5P3N0_CHICK", "mass": { "chemical_mass": 76251.0, "monoisotopic_mass": 76251.0 }, "refseq": { "ac": "XP_417765", "name": "endoribonuclease ZC3H12A", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417765" }, "gene_names": [ { "name": "ZC3H12A", "type": "recommended", "evidence": [ { "id": "A0A1D5P3N0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P3N0" } ] }, { "name": "ZC3H12A", "type": "synonym", "evidence": [ { "id": "XP_417765", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417765" } ] } ], "protein_names": [ { "name": "Zinc finger CCCH-type containing 12A", "type": "synonym", "evidence": [ { "id": "A0A1D5P3N0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P3N0/entry#names_and_taxonomy" } ] }, { "name": "endoribonuclease ZC3H12A", "type": "synonym", "evidence": [ { "id": "XP_417765", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417765" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052554.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 19, 2013 this sequence version replaced XP_417765.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_417765", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417765" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P3N0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P3N0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ZC3H12A", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P3N0", "locus": { "chromosome": "23", "start_pos": 4129510, "end_pos": 4139484, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010016458", "url": "https://www.ensembl.org/id/ENSGALG00010016458" } ] } } ], "crossref": [ { "id": "A0A1D5P3N0", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5P3N0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000002021", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000002021", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd18729", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18729", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "419618", "url": "https://www.ncbi.nlm.nih.gov/gene/419618", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000571", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000571", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021869", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021869", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040546", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040546", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040757", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040757", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051101", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051101", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:419618", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419618", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DMWPYRS", "url": "https://omabrowser.org/oma/group/DMWPYRS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5P3N0", "url": "https://www.orthodb.org/?gene=A0A1D5P3N0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12876", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12876", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12876:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12876:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF11977", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11977", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18039", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18039", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18561", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18561", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_417765", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417765", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5P3N0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P3N0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5P3N0-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P3N0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSVGSVSSLLGCPGWREAFPVLRQQFNRLEERMSSRDTCESGYLSLGQTLSREEGVGPAVLAMEPVGSPTQEPPDSLEMQLKVDFFRKLGYSSEEIYVVLQKLGLNADTNTVLGELVKHGPAERDPTETPQETKEAPLVPRGGAANKTPAPVPPLEEKESDNLKPIVIDGSNVAMSHGNKEVFSCRGILLAVQWFWDRGHKDITVFVPSWRKEQPRPDVLITDQYILRDLEKKKILVFTPSRRVGGKRVVCYDDRFIVKLAHESDGIVVSNDTYRDLQNERPEWKKFIEERLLMYSFVNDKFMPPDDPLGRHGPSLDNFLRKKPVVPEHKKQQCPYGKKCTYGIKCKFYHPERINQPQRSLADELRANARLSPTRSTSAVKEEKKGKRGSQAELLCSVPTESDKSSLQKISAERKSLTHKTKPSDVPLQIKGCVSGSVPANSGSHRSSERYQHPHMDSLSYISQEHLDSGIGSLENQLSDMWPYRSTSHCDHSHAEQVTVCTCGRQRPVYPHSPSLEQNGLVSYKHGSHKSSASGASFLQYNPEIPHSGPPHSFSGYGVPVHPANAGQYSLPSEYNAPSLPSLHSREYWSEPYQMPPPQVRSTSVRDPHSVQRAPGPTYGDSCQWNVSDQFAEERANIHVKLCGIFHPHLVDAVMNRFPQLLDPQKLAAEILTYKSQNPGI", "length": 681, "header": "tr|A0A1D5P3N0-1|A0A1D5P3N0_CHICK Isoform 1 of Zinc finger CCCH-type containing 12A OS=Gallus gallus OX=9031 GN=ZC3H12A PE=3 SV=1 CANONICAL=A0A1D5P3N0-1" }, "isoforms": [ { "isoform_ac": "A0A1D5P3N0-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P3N0/entry#A0A1D5P3N0-1", "sequence": { "sequence": "MSVGSVSSLLGCPGWREAFPVLRQQFNRLEERMSSRDTCESGYLSLGQTLSREEGVGPAVLAMEPVGSPTQEPPDSLEMQLKVDFFRKLGYSSEEIYVVLQKLGLNADTNTVLGELVKHGPAERDPTETPQETKEAPLVPRGGAANKTPAPVPPLEEKESDNLKPIVIDGSNVAMSHGNKEVFSCRGILLAVQWFWDRGHKDITVFVPSWRKEQPRPDVLITDQYILRDLEKKKILVFTPSRRVGGKRVVCYDDRFIVKLAHESDGIVVSNDTYRDLQNERPEWKKFIEERLLMYSFVNDKFMPPDDPLGRHGPSLDNFLRKKPVVPEHKKQQCPYGKKCTYGIKCKFYHPERINQPQRSLADELRANARLSPTRSTSAVKEEKKGKRGSQAELLCSVPTESDKSSLQKISAERKSLTHKTKPSDVPLQIKGCVSGSVPANSGSHRSSERYQHPHMDSLSYISQEHLDSGIGSLENQLSDMWPYRSTSHCDHSHAEQVTVCTCGRQRPVYPHSPSLEQNGLVSYKHGSHKSSASGASFLQYNPEIPHSGPPHSFSGYGVPVHPANAGQYSLPSEYNAPSLPSLHSREYWSEPYQMPPPQVRSTSVRDPHSVQRAPGPTYGDSCQWNVSDQFAEERANIHVKLCGIFHPHLVDAVMNRFPQLLDPQKLAAEILTYKSQNPGI", "length": 681, "header": "tr|A0A1D5P3N0-1|A0A1D5P3N0_CHICK Isoform 1 of Zinc finger CCCH-type containing 12A OS=Gallus gallus OX=9031 GN=ZC3H12A PE=3 SV=1 CANONICAL=A0A1D5P3N0-1" }, "locus": { "chromosome": "23", "start_pos": 4139076, "end_pos": 4131497, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010039636.1", "url": "https://www.ensembl.org/id/ENSGALT00010039636.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022895.1", "url": "https://www.ensembl.org/id/ENSGALP00010022895.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 618, "start_aa": "Thr", "end_pos": 618, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr618", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:419618", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419618", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3L7I7Z6-1", "protein_name": "Endoribonuclease ZC3H12A", "gene_name": "Zc3h12a", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSDPCRKKSVQEASPTMSLWELEDNHSCRGRPQPAQDPEAKEASAELQMKVDFFRKLGYSSSEIHSVLQKLGVQADTNTVLGELVKHGSASERECQASTDPCPQPPLVPRGGSTPKPSEPSLPEEDKDGSDLRPVVIDGSNVAMSHGNKEVFSCRGILLAVNWFLERGHTDITVFVPSWRKEQPRPDVPITDQHILRELEKKKILVFTPSRRVGGKRVVCYDDRFIVKLAYESDGVVVSNDTYRDLQGERQEWKRFIEERLLMYSFVNDKFMPPDDPLGRHGPSLDNFLRKKSLPSEHRKQPCPYGRKCTYGIKCRFFHPERPSRPQRSVADELRANALLSPPRTPVKDKSGPRSSPASQPSSVSPEAEQGSLDGKKLGARSSPGPHQEGSTQTFTAAGRSLPVSGGSFGPTEWFPHTVDSLPYTSQECLDSGIGSLESQMSELWGVRGGSPGESGPARGPYASYHTYGSELPAAPAYTPFRQPMGAGHFSVPGDYVPQPPTFPAREYWSEPYPLPSPTPVLQEPQRPSPGASRGPWDRVNKRAKERADVYTKLCGVFHPHLVEAVMGRFPQLLDPQQLAAEILSYKSQHLSE", "length": 593 }, "evidence": [ { "id": "A0A1D5P3N0", "url": "https://omabrowser.org/oma/group/A0A1D5P3N0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0JPN4-1", "protein_name": "Endoribonuclease ZC3H12A", "gene_name": "Zc3h12a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSDPCGKKLVQEISPTMSLWGLEDRHSCQGQPQPDQDPVAKEASASELQMKVDFFRKLGYSSSEIHSALQKLGVQADTNTVLGELVKHGSATERECQASTDPCPQPPLVPRGGSTPKPSTVEPSLPEEDKESSDLRPVVIDGSNVAMSHGNKEVFSCRGILLAVNWFLERGHTDITVFVPSWRKEQPRPDVPITDQHILRELEKKKILVFTPSRRVGGKRVVCYDDRFIVKLAYESDGVVVSNDTYRDLQGERQEWKRFIEERLLMYSFVNDKFMPPDDPLGRHGPSLDNFLRKKPLPSEHRKQPCPYGRKCTYGIKCRFFHPERPSRPQRSVADELRANALLSPPRTPVKDKSSQRPSPASQPNSMSLEAEPGSPDGKKLGTRSSPGPHQEGSTQTCAPAGRSLPVSGGSFGPTEWLPHTLDSLPYTSQECLDSGIGSLESQMSELWGLRGGSPGESGPTRGPYTGYQTYGSKLPAAPAFSPFRQAIGTGHFSVPTDYVPPPPTYPAREYWSEPYPLPPPTPVLQEPQRPRPRASGDPWGRVSDLAKERAGVYTKLCGVFPPHLVEAVMGRFPQLLDPQQLAAEILSYKSQHLSE", "length": 596 }, "evidence": [ { "id": "A0A1D5P3N0", "url": "https://omabrowser.org/oma/group/A0A1D5P3N0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A6QQJ8-1", "protein_name": "Ribonuclease ZC3H12A", "gene_name": "ZC3H12A", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSLWELEDRRSCQGTPRPAQEPTAEEATTAELQMKVDFFRKLGYSSAEIHSVLQKLGIQADTNTVLGELVKHGSAAERERQASPDPCPQLPLVPRGGGTPKAPTVETYPPEEDKEGSDLRPIVIDGSNVAMSHGNKDVFSCRGILLAVNWFLERGHTDITVFVPSWRKEQPRPDVPITDQHILRDLEKKKILVFTPSRRVGGKRVVCYDDRFIVKLAFESDGIVVSNDTYRDLQGERQEWKRFIEERLLMYSFVNDKFMPPDDPLGRHGPSLDNFLRKKPLTSEHKKQPCPYGRKCTYGIKCRFLHPERPSRPQRSVADELRANALLPPSRAASKDKNSRRPSPSSQPGSLPTEHEQCSPDRKKLGAQASPGTPREGLMQTFAPTGRSLPPSGSSGGSFGPSEWFPQTLDSLPYASQDCLDSGIGSLESQMSELWGVRGGGPGEPGPPRGPYAGYCTYGAELPATPAFSAFSRALGAGHFSVPADYAPPPAAFPPREYWSEPYQLPPPTQRLQEPQAPGPGADRGPWGGAGRLAKERASVYTKLCGVFPPHLVEAVMSRFPQLLDPQQLAAEILSYKSQHLSE", "length": 583 }, "evidence": [ { "id": "A0A1D5P3N0", "url": "https://omabrowser.org/oma/group/A0A1D5P3N0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q5D1E7-1", "protein_name": "Endoribonuclease ZC3H12A", "gene_name": "Zc3h12a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDPCGTKPVQESNPTMSLWSLEDRHSSQGRPQPDQDPVAKEAPTSELQMKVDFFRKLGYSSSEIHSVLQKLGVQADTNTVLGELVKHGSATERECQALTAPSPQPPLVPRGGSTPKPSTLEPSLPEEDREGSDLRPVVIDGSNVAMSHGNKEVFSCRGILLAVNWFLERGHTDITVFVPSWRKEQPRPDVPITDQHILRELEKKKILVFTPSRRVGGKRVVCYDDRFIVKLAFESDGVVVSNDTYRDLQGERQEWKRFIEERLLMYSFVNDKFMPPDDPLGRHGPSLDNFLRKKPLPSEHRKQPCPYGKKCTYGIKCRFFHPERPSRPQRSVADELRANALLSPPRTPVKDKSSQRPSPASQSSSVSLEAEPGSLDGKKLGARSSPGPHREGSPQTCAPAGRSLPVSGGSFGPTEWLAHTQDSLPYTSQECLDSGIGSLESQMSELWGVRGGSPGESGPTRGPYAGYHSYGSKVPAAPSFSPFRPAMGAGHFSVPTDYVPPPPTYPSREYWSEPYPLPPPTPVLQEPQRPSPGAGGGPWGRVGDLAKERAGVYTKLCGVFPPHLVEAVMRRFPQLLDPQQLAAEILSYKSQHLSE", "length": 596 }, "evidence": [ { "id": "A0A1D5P3N0", "url": "https://omabrowser.org/oma/group/A0A1D5P3N0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5D1E8-1", "protein_name": "Endoribonuclease ZC3H12A", "gene_name": "ZC3H12A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSGPCGEKPVLEASPTMSLWEFEDSHSRQGTPRPGQELAAEEASALELQMKVDFFRKLGYSSTEIHSVLQKLGVQADTNTVLGELVKHGTATERERQTSPDPCPQLPLVPRGGGTPKAPNLEPPLPEEEKEGSDLRPVVIDGSNVAMSHGNKEVFSCRGILLAVNWFLERGHTDITVFVPSWRKEQPRPDVPITDQHILRELEKKKILVFTPSRRVGGKRVVCYDDRFIVKLAYESDGIVVSNDTYRDLQGERQEWKRFIEERLLMYSFVNDKFMPPDDPLGRHGPSLDNFLRKKPLTLEHRKQPCPYGRKCTYGIKCRFFHPERPSCPQRSVADELRANALLSPPRAPSKDKNGRRPSPSSQSSSLLTESEQCSLDGKKLGAQASPGSRQEGLTQTYAPSGRSLAPSGGSGSSFGPTDWLPQTLDSLPYVSQDCLDSGIGSLESQMSELWGVRGGGPGEPGPPRAPYTGYSPYGSELPATAAFSAFGRAMGAGHFSVPADYPPAPPAFPPREYWSEPYPLPPPTSVLQEPPVQSPGAGRSPWGRAGSLAKEQASVYTKLCGVFPPHLVEAVMGRFPQLLDPQQLAAEILSYKSQHPSE", "length": 599 }, "evidence": [ { "id": "A0A1D5P3N0", "url": "https://omabrowser.org/oma/group/A0A1D5P3N0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 42, "go_terms": [ { "name": "positive regulation of protein import into nucleus", "id": "GO:0042307", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042307", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P3N0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P3N0" } ], "pmid": "" }, { "name": "cellular response to chemokine", "id": "GO:1990869", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990869", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P3N0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P3N0" } ], "pmid": "" }, { "name": "negative regulation of T-helper 17 cell differentiation", "id": "GO:2000320", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000320", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P3N0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P3N0" } ], "pmid": "" }, { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P3N0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P3N0" } ], "pmid": "" }, { "name": "positive regulation of gene expression", "id": "GO:0010628", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010628", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P3N0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P3N0" } ], "pmid": "" }, { "name": "protein deubiquitination", "id": "GO:0016579", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016579", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P3N0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P3N0" } ], "pmid": "" }, { "name": "positive regulation of fat cell differentiation", "id": "GO:0045600", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045600", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P3N0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P3N0" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P3N0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P3N0" } ], "pmid": "" }, { "name": "protein complex oligomerization", "id": "GO:0051259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051259", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P3N0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P3N0" } ], "pmid": "" }, { "name": "positive regulation of endothelial cell migration", "id": "GO:0010595", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010595", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P3N0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P3N0" } ], "pmid": "" }, { "name": "positive regulation of lipid storage", "id": "GO:0010884", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010884", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P3N0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P3N0" } ], "pmid": "" }, { "name": "negative regulation of type II interferon production", "id": "GO:0032689", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032689", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P3N0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P3N0" } ], "pmid": "" }, { "name": "negative regulation of interleukin-1 beta production", "id": "GO:0032691", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032691", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P3N0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P3N0" } ], "pmid": "" }, { "name": "negative regulation of interleukin-6 production", "id": "GO:0032715", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032715", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P3N0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P3N0" } ], "pmid": "" }, { "name": "negative regulation of tumor necrosis factor production", "id": "GO:0032720", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032720", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P3N0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P3N0" } ], "pmid": "" }, { "name": "positive regulation of angiogenesis", "id": "GO:0045766", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045766", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P3N0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P3N0" } ], "pmid": "" }, { "name": "T cell receptor signaling pathway", "id": "GO:0050852", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050852", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P3N0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P3N0" } ], "pmid": "" }, { "name": "negative regulation of cardiac muscle contraction", "id": "GO:0055118", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055118", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P3N0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P3N0" } ], "pmid": "" }, { "name": "cellular response to lipopolysaccharide", "id": "GO:0071222", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071222", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P3N0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P3N0" } ], "pmid": "" }, { "name": "DNA damage response", "id": "GO:0006974", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006974", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P3N0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P3N0" } ], "pmid": "" }, { "name": "cellular response to oxidative stress", "id": "GO:0034599", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034599", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P3N0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P3N0" } ], "pmid": "" }, { "name": "negative regulation of canonical NF-kappaB signal transduction", "id": "GO:0043124", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043124", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P3N0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P3N0" } ], "pmid": "" }, { "name": "positive regulation of reactive oxygen species metabolic process", "id": "GO:2000379", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000379", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P3N0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P3N0" } ], "pmid": "" }, { "name": "positive regulation of defense response to virus by host", "id": "GO:0002230", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002230", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P3N0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P3N0" } ], "pmid": "" }, { "name": "positive regulation of autophagy", "id": "GO:0010508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010508", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P3N0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P3N0" } ], "pmid": "" }, { "name": "cellular response to glucose starvation", "id": "GO:0042149", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042149", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P3N0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P3N0" } ], "pmid": "" }, { "name": "negative regulation of non-canonical NF-kappaB signal transduction", "id": "GO:1901223", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901223", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P3N0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P3N0" } ], "pmid": "" }, { "name": "negative regulation of cytokine production involved in inflammatory response", "id": "GO:1900016", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900016", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P3N0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P3N0" } ], "pmid": "" }, { "name": "positive regulation of p38MAPK cascade", "id": "GO:1900745", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900745", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P3N0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P3N0" } ], "pmid": "" }, { "name": "mRNA catabolic process", "id": "GO:0006402", "url": 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The reference sequence was derived from JAENSK010000012.1. On Sep 30, 2021 this sequence version replaced NP_989743.1.", "evidence": [ { "database": "RefSeq", "id": "NP_989743", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989743" } ] }, { "annotation": "A BMP-mediated transcriptional cascade involving Cash1 and Tlx-3 specifies first-order relay sensory neurons in the developing brainstem", "evidence": [ { "database": "RefSeq", "id": "NP_989743", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989743" }, { "database": "PubMed", "id": "15922575", "url": "https://glygen.org/publication/PubMed/15922575" } ] }, { "annotation": "Induces neuronal differentiation characterized by the expression of generic neuronal genes SCG10, Hu and NF160", "evidence": [ { "database": "RefSeq", "id": "NP_989743", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989743" }, { "database": "PubMed", "id": "15033166", "url": "https://glygen.org/publication/PubMed/15033166" } ] }, { "annotation": "There is a functional relationship between specific MTG and bHLH proteins 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"GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015660", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015660", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036638", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036638", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:386573", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:386573", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QPAACFF", "url": "https://omabrowser.org/oma/group/QPAACFF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5P4G9", "url": "https://www.orthodb.org/?gene=A0A1D5P4G9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13935", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13935", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13935:SF153", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13935:SF153", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00010", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00010", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_989743", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989743", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5P4G9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P4G9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5P4G9-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P4G9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASGSPAGMASGQPPFLQPACFFAAAVAAAAAAAPPGPPPGAPPPPLPQLSPAGGRPSPGGKPSAARAAKRQRSASPELMRCKRRLNFSGFGYSLPQQQPAAVARRNERERNRVKLVNLGFATLREHVPNGAANKKMSKVETLRSAVEYIRALQQLLDEHDAVSAAFQAGVLSPTISPGYSHDMNSMAGSPVSSYSSDEGSYDPLSPEEQELLDFTSWF", "length": 219, "header": "tr|A0A1D5P4G9-1|A0A1D5P4G9_CHICK Isoform 1 of Achaete-scute family bHLH transcription factor 1 OS=Gallus gallus OX=9031 GN=ASCL1 PE=4 SV=1 CANONICAL=A0A1D5P4G9-1" }, "isoforms": [ { "isoform_ac": "A0A1D5P4G9-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P4G9/entry#A0A1D5P4G9-1", "sequence": { "sequence": "MASGSPAGMASGQPPFLQPACFFAAAVAAAAAAAPPGPPPGAPPPPLPQLSPAGGRPSPGGKPSAARAAKRQRSASPELMRCKRRLNFSGFGYSLPQQQPAAVARRNERERNRVKLVNLGFATLREHVPNGAANKKMSKVETLRSAVEYIRALQQLLDEHDAVSAAFQAGVLSPTISPGYSHDMNSMAGSPVSSYSSDEGSYDPLSPEEQELLDFTSWF", "length": 219, "header": "tr|A0A1D5P4G9-1|A0A1D5P4G9_CHICK Isoform 1 of Achaete-scute family bHLH transcription factor 1 OS=Gallus gallus OX=9031 GN=ASCL1 PE=4 SV=1 CANONICAL=A0A1D5P4G9-1" }, "locus": { "chromosome": "1", "start_pos": 55112740, "end_pos": 55112084, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026479.1", "url": "https://www.ensembl.org/id/ENSGALT00010026479.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015074.1", "url": "https://www.ensembl.org/id/ENSGALP00010015074.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Interaction of Mash1 and Phox2b in sympathetic neuron development.", "journal": "Molecular and cellular neurosciences", "date": "2004-03", "authors": "Stanke Matthias, Stubbusch Jutta, Rohrer Hermann", "evidence": [ { "database": "RefSeq", "id": "NP_989743", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989743" } ], "reference": [ { "type": "PubMed", "id": "15033166", "url": "https://glygen.org/publication/PubMed/15033166" } ] }, { "title": "A BMP-mediated transcriptional cascade involving Cash1 and Tlx-3 specifies first-order relay sensory neurons in the developing hindbrain.", "journal": "Mechanisms of development", "date": "2005-07", "authors": "Hornbruch Amata, Ma Grace, Ballermann Mark A, Tumova Katerina, Liu Dan, Cairine Logan C", "evidence": [ { "database": "RefSeq", "id": "NP_989743", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989743" } ], "reference": [ { "type": "PubMed", "id": "15922575", "url": "https://glygen.org/publication/PubMed/15922575" } ] }, { "title": "Reprogramming chick RPE progeny cells to differentiate towards retinal neurons by ash1.", "journal": "Molecular vision", "date": "2008", "authors": "Mao Weiming, Yan Run-Tao, Wang Shu-Zhen", "evidence": [ { "database": "RefSeq", "id": "NP_989743", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989743" } ], "reference": [ { "type": "PubMed", "id": "19093008", "url": "https://glygen.org/publication/PubMed/19093008" } ] }, { "title": "Interaction of MTG family proteins with NEUROG2 and ASCL1 in the developing nervous system.", "journal": "Neuroscience letters", "date": "2010-04-19", "authors": "Aaker Joshua D, Patineau Andrea L, Yang Hyun-Jin, Ewart David T, Nakagawa Yasushi, McLoon Steven C, Koyano-Nakagawa Naoko", "evidence": [ { "database": "RefSeq", "id": "NP_989743", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989743" } ], "reference": [ { "type": "PubMed", "id": "20214951", "url": "https://glygen.org/publication/PubMed/20214951" } ] } ], "pathway": [ { "id": "gga:386573", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:386573", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8W4FIB1-1", "protein_name": "Achaete-scute family bHLH transcription factor 1", "gene_name": "ASCL1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MESSAKMESGGGAGQQPQPQPQQPFLPPAACFFATAAAAAAAAAAAAAQSAQQPPPQAPQAPQLSPAGDGQPSGGGHKSGPKQVKRQRSSSPELMRCKRRLNFSGFGYSLPQQQPAAVARRNERERNRVKLVNLGFATLREHVPNGAANKKMSKVETLRSAVEYIRALQQLLDEHDAVSAAFQAGVLSPTISPNYSNDMNSMAGSPVSSYSSDEGSYDPLSPEEQELLDFTNWF", "length": 234 }, "evidence": [ { "id": "A0A1D5P4G9", "url": "https://omabrowser.org/oma/group/A0A1D5P4G9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0AAA9TS24-1", "protein_name": "Achaete-scute family bHLH transcription factor 1", "gene_name": "ASCL1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MESSAKMESGGAGPQPQQPFLPPAACFFATAAAQSAQQPPPPPPPPPQLSPAADGQPSGGGHKSAPKQVKRQRSSSPELMRCKRRLNFSGFGYSLPQQQPAAVARRNERERNRVKLVNLGFATLREHVPNGAANKKMSKVETLRSAVEYIRALQQLLDEHDAVSAAFQAGVLSPTISPNYSNDMNSMAGSPVSSYSSDEGSYDPLSPEEQELLDFTNWF", "length": 219 }, "evidence": [ { "id": "A0A1D5P4G9", "url": "https://omabrowser.org/oma/group/A0A1D5P4G9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P19359-1", "protein_name": "Achaete-scute homolog 1", "gene_name": "Ascl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MESSGKMESGAGQQPQPPQPFLPPAACFFATAAAAAAAAAAAAAQSAQQQQQQQAPQQQAPQLSPVADGQPSGGGHKSAAKQVKRQRSSSPELMRCKRRLNFSGFGYSLPQQQPAAVARRNERERNRVKLVNLGFATLREHVPNGAANKKMSKVETLRSAVEYIRALQQLLDEHDAVSAAFQAGVLSPTISPNYSNDLNSMAGSPVSSYSSDEGSYDPLSPEEQELLDFTNWF", "length": 233 }, "evidence": [ { "id": "A0A1D5P4G9", "url": "https://omabrowser.org/oma/group/A0A1D5P4G9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P50553-1", "protein_name": "Achaete-scute homolog 1", "gene_name": "ASCL1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MESSAKMESGGAGQQPQPQPQQPFLPPAACFFATAAAAAAAAAAAAAQSAQQQQQQQQQQQQAPQLRPAADGQPSGGGHKSAPKQVKRQRSSSPELMRCKRRLNFSGFGYSLPQQQPAAVARRNERERNRVKLVNLGFATLREHVPNGAANKKMSKVETLRSAVEYIRALQQLLDEHDAVSAAFQAGVLSPTISPNYSNDLNSMAGSPVSSYSSDEGSYDPLSPEEQELLDFTNWF", "length": 236 }, "evidence": [ { "id": "A0A1D5P4G9", "url": "https://omabrowser.org/oma/group/A0A1D5P4G9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q02067-1", "protein_name": "Achaete-scute homolog 1", "gene_name": "Ascl1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESSGKMESGAGQQPQPPQPFLPPAACFFATAAAAAAAAAAAAQSAQQQQPQAPPQQAPQLSPVADSQPSGGGHKSAAKQVKRQRSSSPELMRCKRRLNFSGFGYSLPQQQPAAVARRNERERNRVKLVNLGFATLREHVPNGAANKKMSKVETLRSAVEYIRALQQLLDEHDAVSAAFQAGVLSPTISPNYSNDLNSMAGSPVSSYSSDEGSYDPLSPEEQELLDFTNWF", "length": 231 }, "evidence": [ { "id": "A0A1D5P4G9", "url": "https://omabrowser.org/oma/group/A0A1D5P4G9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q90259-1", "protein_name": "Achaete-scute homolog 1a", "gene_name": "ascl1a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDITAKMEISVNQQQFMPPACFFASQSIQLSPTDSQCSNKSASKQAKRQRSSSPELLRCKRRLNFAGFGYSLPQQQPHAVARRNERERNRVKLVNNGFATLREHVPNGAANKKMSKVETLRSAVEYIRALQQLLDEHDAVSAAFQSGVLSPTISQNYSNDMNSMAGSPVSSYSSDEGSYDPLSPEEQELLDFTNWF", "length": 196 }, "evidence": [ { "id": "A0A1D5P4G9", "url": "https://omabrowser.org/oma/group/A0A1D5P4G9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 7, "go_terms": [ { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P4G9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P4G9" } ], "pmid": "" }, { "name": "protein dimerization activity", "id": "GO:0046983", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046983", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P4G9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P4G9" } ], "pmid": "" }, { "name": "RNA polymerase II transcription regulatory region sequence-specific DNA binding", "id": "GO:0000977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000977", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P4G9", "url": 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"https://www.uniprot.org/uniprotkb/A0A1D5P4G9" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P4G9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P4G9" } ], "pmid": "" }, { "name": "response to retinoic acid", "id": "GO:0032526", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032526", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P4G9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P4G9" } ], "pmid": "" }, { "name": "neuron differentiation", "id": "GO:0030182", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030182", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P4G9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P4G9" } ], "pmid": "" }, { "name": "noradrenergic neuron development", "id": "GO:0003358", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003358", "evidence": [ { "database": 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"https://www.uniprot.org/uniprotkb/A0A1D5P8D7" } ], "pmid": "" }, { "name": "smoothened signaling pathway", "id": "GO:0007224", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007224", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P8D7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P8D7" } ], "pmid": "" }, { "name": "pattern specification process", "id": "GO:0007389", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007389", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P8D7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P8D7" } ], "pmid": "" }, { "name": "positive regulation of multicellular organism growth", "id": "GO:0040018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0040018", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P8D7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P8D7" } ], "pmid": "" }, { "name": "forebrain morphogenesis", "id": "GO:0048853", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048853", "evidence": [ { "database": "UniProtKB", 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] }, { "id": "A0A8V0YY43", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YY43", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YY43-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YY43-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFRSKRSGLVRRLWRSRVIPERDGGDGNGQSSERNATAVTAEGQRMAQPRRAQEGEGRPVRCCLFAERPGPELPPPPPPPPPGGASPPGPGGGEARSRLVLLERELKAVTYALLKRLKERSLHSLLQAVESRGGTPGGCVLVARGELRLGGGQAAPPHLLLGKLFRWPDLQHPAELKALCECQSFGAADGPTVCCNPYHFSRLCGPESPPPPYSRLSPNDEQKPLDLSDSTLSYTETEATNSPNVTPGEFSDASTSPDAVKRSHWCNVAYWEHRTRVGRLYTVYEQSVSIFYDLPQGNGFCLGQLNLENRSETVRRTRSKIGYGILLSKEPDGVWAYNRSEHPIFVNSPTLDIPNCRTLIVRKVMPGYSIKVFDYEKSCLLQHTAELDYADGPYDPNSVRISFAKGWGPCYSRQFITSCPCWLEILLSNNR", "length": 431, "header": "tr|A0A1D5PB14-1|A0A1D5PB14_CHICK Isoform 1 of Mothers against decapentaplegic homolog OS=Gallus gallus OX=9031 GN=SMAD6 PE=3 SV=2 CANONICAL=A0A1D5PB14-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PB14-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PB14/entry#A0A1D5PB14-1", "sequence": { "sequence": "MFRSKRSGLVRRLWRSRVIPERDGGDGNGQSSERNATAVTAEGQRMAQPRRAQEGEGRPVRCCLFAERPGPELPPPPPPPPPGGASPPGPGGGEARSRLVLLERELKAVTYALLKRLKERSLHSLLQAVESRGGTPGGCVLVARGELRLGGGQAAPPHLLLGKLFRWPDLQHPAELKALCECQSFGAADGPTVCCNPYHFSRLCGPESPPPPYSRLSPNDEQKPLDLSDSTLSYTETEATNSPNVTPGEFSDASTSPDAVKRSHWCNVAYWEHRTRVGRLYTVYEQSVSIFYDLPQGNGFCLGQLNLENRSETVRRTRSKIGYGILLSKEPDGVWAYNRSEHPIFVNSPTLDIPNCRTLIVRKVMPGYSIKVFDYEKSCLLQHTAELDYADGPYDPNSVRISFAKGWGPCYSRQFITSCPCWLEILLSNNR", "length": 431, "header": "tr|A0A1D5PB14-1|A0A1D5PB14_CHICK Isoform 1 of Mothers against decapentaplegic homolog OS=Gallus gallus OX=9031 GN=SMAD6 PE=3 SV=2 CANONICAL=A0A1D5PB14-1" }, "locus": { "chromosome": "10", "start_pos": 18729100, "end_pos": 18702173, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043662.1", "url": "https://www.ensembl.org/id/ENSGALT00010043662.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025978.1", "url": "https://www.ensembl.org/id/ENSGALP00010025978.1" } ] } }, { "isoform_ac": "A0A8V0YY43-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PB14/entry#A0A8V0YY43-1", "sequence": { "sequence": "MFRSKRSGLVRRLWRSRVIPERDGGDGNGQSSERNATAVTAEGQRMAQPRRAQEGEGRPVRCCLFAERPGPELPPPPPPPPPGGASPPGPGGGEARSRLVLLERELKAVTYALLKRLKERSLHSLLQAVESRGGTPGGCVLVARGELRLGGGQAAPPHLLLGKLFRWPDLQHPAELKALCECQSFGAADGPTVCCNPYHFSRLCGPDLSDSTLSYTETEATNSPNVTPGEFSDASTSPDAVKRSHWCNVAYWEHRTRVGRLYTVYEQSVSIFYDLPQGNGFCLGQLNLENRSETVRRTRSKIGYGILLSKEPDGVWAYNRSEHPIFVNSPTLDIPNCRTLIVRKVMPGYSIKVFDYEKSCLLQHTAELDYADGPYDPNSVRISFAKGWGPCYSRQFITSCPCWLEILLSNNR", "length": 412, "header": "tr|A0A8V0YY43-1|A0A1D5PB14_CHICK Computationally mapped isoform of Mothers against decapentaplegic homolog OS=Gallus gallus OX=9031 GN=SMAD6 PE=3 SV=1 CANONICAL=A0A1D5PB14-1" }, "locus": { "chromosome": "10", "start_pos": 18729100, "end_pos": 18702173, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043644.1", "url": "https://www.ensembl.org/id/ENSGALT00010043644.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025965.1", "url": "https://www.ensembl.org/id/ENSGALP00010025965.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 192, "start_aa": "Thr", "end_pos": 192, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr192", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 246, "start_aa": "Thr", "end_pos": 246, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr246", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "Negative Smad expression and regulation in the developing chick limb.", "journal": "PloS one", "date": "2009", "authors": "Vargesson Neil, Laufer Ed", "evidence": [ { "database": "RefSeq", "id": "NP_989579", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989579" } ], "reference": [ { "type": "PubMed", "id": "19352514", "url": "https://glygen.org/publication/PubMed/19352514" } ] }, { "title": "Smad6 promotes neuronal differentiation in the intermediate zone of the dorsal neural tube by inhibition of the Wnt/beta-catenin pathway.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2011-07-19", "authors": "Xie Zhihui, Chen Yongfeng, Li Zhenfei, Bai Ge, Zhu Yue, Yan Rui, Tan Fangzhi, Chen Ye-Guang, Guillemot Francois, Li Lin, Jing Naihe", "evidence": [ { "database": "RefSeq", "id": "NP_989579", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989579" } ], "reference": [ { "type": "PubMed", "id": "21730158", "url": "https://glygen.org/publication/PubMed/21730158" } ] } ], "pathway": [ { "id": "gga:374096", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:374096", "resource": "KEGG Pathway" }, { "id": "R-GGA-201451", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-201451", "resource": "Reactome", "description": "Signaling by BMP" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1MTU6-1", "protein_name": "Mothers against decapentaplegic homolog", "gene_name": "SMAD6", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MFRSKRSGLVRRLWRSRVVPDREEGGGSGGGGGDEDGSVGSRAEPAARAREGGGCGRPEVRPVALRRPRDAVGQRGAQGAGRRRRSGGPPRPMSEPGAGSGGSSLDVGEPGGQGWLPESDCETVTCCLFSERDAAGAPREAGEPLVGAAQEPEGGGRSREARSRLLLLEQELKTVTYSLLKRLKERSLDTLLEAVESRGGVPGGCVLVPRADLRLGGQPAPPQLLLGRLFRWPDLQHAVELKPLCGCHSFAAAADGPTVCCNPYHFSRLCGPESPPPPYSRLSPRDEYKPLDLSDSTLSYTETEAANSLITAPGEFSDASMSPDATKPSHWCSVAYWEHRTRVGRLYAVYDQAVSIFYDLPQGSGFCLGQLNLEQRSESVRRTRSKIGFGILLSKEPDGVWAYNRGEHPIFVNSPTLDAPGGRALVVRKVPPGYSIKVFDFERSGLLQHGPEPDAADGPYDPNSVRISFAKGWGPCYSRQFITSCPCWLEILLNNHR", "length": 497 }, "evidence": [ { "id": "A0A1D5PB14", "url": "https://omabrowser.org/oma/group/A0A1D5PB14/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "D3ZAQ2-1", "protein_name": "Mothers against decapentaplegic homolog", "gene_name": "Smad6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFRSKRSGLVRRLWRSRVVPDREEGSGGGCGGDEDGSLGSRAEPAPRAREGGGCGRSEVRSVAPRRLRDAVGPRGALIAGRRRRTGGPPRPVSEPGAGAGGSPLDVVEPGGPGWLPESDCETVTCCLFSERDAAGAPRDSGDPQARQSPEPEEGGGPRSREARSRLLLLEQELKTVTYSLLKRLKERSLDTLLEAVESRGGVPGGCVLVPRADLRLGGQPAPPQLLLGRLFRWPDLQHAVELKPLCGCHSFAAAADGPTVCCNPYHFSRLCGPESPPPPYSRLSPPDQHKPLDLSDSTLSYTETEATNSLITAPGEFSDASMSPDATKPSHWCSVAYWEHRTRVGRLYAVYDQAVSIFYDLPQGSGFCLGQLNLEQRSESVRRTRSKIGFGILLSKEPDGVWAYNRGEHPIFVNSPTLDAPGGRALVVRKVPPGYSIKVFDFERSGLLQHADAAHGPYDPHSVRISFAKGWGPCYSRQFITSCPCWLEILLNNHR", "length": 495 }, "evidence": [ { "id": "A0A1D5PB14", "url": "https://omabrowser.org/oma/group/A0A1D5PB14/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1SJJ2-1", "protein_name": "Mothers against decapentaplegic homolog", "gene_name": "SMAD6", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MFRSKRSGLVRRLWRSRVVPDREEGGGSGGGGDEDGSEGSRAEPAPRPREGGGCSRPEVRPVALRRPRDAVGQRGAQGAGRRRRAGGPPRPMSEPGAGAGGSPLDVSEPGGRGWLPESDCETVTCCLFTERDAAGAPRDAGDPLAGAALEAAGSGRSREARSRLLLLEQELKTVTYSLLKRLKERSLDTLLEAVESRGGVPGGCVLVPRADLRLGGQPAPPQLLLGRLFRWPDLQHAVELKPLCGCHSFAAAADGPTVCCNPYHFSRLCGPESPPPPYSRLSPRDEYKPLDLSDSTLSYTETEATNSLITAPGEFSDASMSPDATKPSHWCSVAYWEHRTRVGRLYAVYDQAVSIFYDLPQGSGFCLGQLNLEQRSESVRRTRSKIGFGILLSKEPDGVWAYNRGEHPIFVNSPTLDAPGGRALVVRKVPPGYSIKVFDFERSGLLQHGPEPDAADGPYDPNSVRISFAKGWGPCYSRQFITSCPCWLEILLNNHR", "length": 496 }, "evidence": [ { "id": "A0A1D5PB14", "url": "https://omabrowser.org/oma/group/A0A1D5PB14/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O35182-1", "protein_name": "SMAD family member 6", "gene_name": "Smad6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFRSKRSGLVRRLWRSRVVPDREEGSGGGGGVDEDGSLGSRAEPAPRAREGGGCSRSEVRSVAPRRPRDAVGPRGAAIAGRRRRTGGLPRPVSESGAGAGGSPLDVAEPGGPGWLPESDCETVTCCLFSERDAAGAPRDSGDPQARQSPEPEEGGGPRSREARSRLLLLEQELKTVTYSLLKRLKERSLDTLLEAVESRGGVPGGCVLVPRADLRLGGQPAPPQLLLGRLFRWPDLQHAVELKPLCGCHSFTAAADGPTVCCNPYHFSRLCGPESPPPPYSRLSPPDQYKPLDLSDSTLSYTETEATNSLITAPGEFSDASMSPDATKPSHWCSVAYWEHRTRVGRLYAVYDQAVSIFYDLPQGSGFCLGQLNLEQRSESVRRTRSKIGFGILLSKEPDGVWAYNRGEHPIFVNSPTLDAPGGRALVVRKVPPGYSIKVFDFERSGLLQHADAAHGPYDPHSVRISFAKGWGPCYSRQFITSCPCWLEILLNNHR", "length": 495 }, "evidence": [ { "id": "A0A1D5PB14", "url": "https://omabrowser.org/oma/group/A0A1D5PB14/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "O43541-1", "protein_name": "SMAD family member 6", "gene_name": "SMAD6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MFRSKRSGLVRRLWRSRVVPDREEGGSGGGGGGDEDGSLGSRAEPAPRAREGGGCGRSEVRPVAPRRPRDAVGQRGAQGAGRRRRAGGPPRPMSEPGAGAGSSLLDVAEPGGPGWLPESDCETVTCCLFSERDAAGAPRDASDPLAGAALEPAGGGRSREARSRLLLLEQELKTVTYSLLKRLKERSLDTLLEAVESRGGVPGGCVLVPRADLRLGGQPAPPQLLLGRLFRWPDLQHAVELKPLCGCHSFAAAADGPTVCCNPYHFSRLCGPESPPPPYSRLSPRDEYKPLDLSDSTLSYTETEATNSLITAPGEFSDASMSPDATKPSHWCSVAYWEHRTRVGRLYAVYDQAVSIFYDLPQGSGFCLGQLNLEQRSESVRRTRSKIGFGILLSKEPDGVWAYNRGEHPIFVNSPTLDAPGGRALVVRKVPPGYSIKVFDFERSGLQHAPEPDAADGPYDPNSVRISFAKGWGPCYSRQFITSCPCWLEILLNNPR", "length": 496 }, "evidence": [ { "id": "A0A1D5PB14", "url": "https://omabrowser.org/oma/group/A0A1D5PB14/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 12, "go_terms": [ { "name": "co-SMAD binding", "id": "GO:0070410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070410", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PB14", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PB14" } ], "pmid": "" }, { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PB14", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PB14" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PB14", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PB14" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PB14", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PB14" } ], "pmid": "" }, { "name": "ubiquitin protein ligase binding", "id": "GO:0031625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031625", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PB14", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PB14" } ], "pmid": "" }, { "name": "transcription cis-regulatory region binding", "id": "GO:0000976", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000976", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PB14", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PB14" } ], "pmid": "" }, { "name": "R-SMAD binding", "id": "GO:0070412", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070412", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PB14", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PB14" } ], "pmid": "" }, { "name": "I-SMAD binding", "id": "GO:0070411", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070411", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PB14", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PB14" } ], "pmid": "" }, { "name": "type I transforming growth factor beta receptor binding", "id": "GO:0034713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034713", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PB14", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PB14" } ], "pmid": "" }, { "name": "type I activin receptor binding", "id": "GO:0070698", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070698", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PB14", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PB14" } ], "pmid": "" }, { "name": "transcription regulator inhibitor activity", "id": "GO:0140416", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140416", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PB14", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PB14" } ], "pmid": "" }, { "name": "protein sequestering activity", "id": "GO:0140311", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140311", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PB14", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PB14" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "heteromeric SMAD protein complex", "id": "GO:0071144", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071144", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PB14", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PB14" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PB14", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PB14" } ], "pmid": "" }, { "name": "nuclear body", "id": "GO:0016604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016604", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PB14", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PB14" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PB14", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PB14" } ], "pmid": "" }, { "name": "transcription regulator complex", "id": "GO:0005667", "url": 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"id": "R-GGA-196299", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-196299", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-3769402", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3769402", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5689896", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5689896", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_046761944", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046761944", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PC88", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PC88", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PC88-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PC88-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XXR0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXR0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XXR0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXR0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XZP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XZP1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XZP1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XZP1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y267", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y267", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y267-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y267-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y647", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y647", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y647-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y647-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAASYDQLLKQVEALKMENSNLRQELEDNSNHLTKLETEASNMKMVDPAGICTYLEEVLKQLQGSIEDEAIASSGQIDLLERLKELNLESTSFPGVKLRQKVSVRSYGSREGSVSSRSGECSPVPMGSFPRRGFMNGSRESTGYLEELEKERSLLLAELEKEEKEKDWYYAQLQNLTKRIDSLPLTENFSLQTDMTRRQLEYEARQIRAAMEEQLGTCQDMEKRAQVRVARIQQIEKDILRIRQLLQSQAAEAERAPQGKHDAASHDTERQSEGQGAPEISMSTSNTGQGSAARMDHETASVMSSSNNYSVPRRLTSHLGTKVEMVYSLLSMLGTHDKDDMSRTLLAMSSSQDSCIAMRQSGCLPLLIQLLHGNDKDSVLLGNSRGSKEARARASAALHNIIHSQPDDKRGRREIRVLHLLEQIRAYCETCWEWQEAHEQGMDQDKNPMPAPVDHQICPAVCVLMKLSFDEEHRHAMNELGGLQAIAELLQVDCEMYGLTNDHYSVTLRRYAGMALTNLTFGDVANKATLCSMKGCMRALVAQLKSESEDLQQVIASVLRNLSWRADVNSKKTLREVGSVKALMECALEVKKESTLKSVLSALWNLSAHCTENKADICAVDGALAFLVGTLTYRSQTNTLAIIESGGGILRNVSSLIATNEDHRQILRENSCLQTLLQHLKSHSLTIVSNACGTLWNLSARNAKDQEALWDMGAVSMLKNLIHSKHKMIAMGSAAALRNLMANRPAKYKDTNIMSPGSSLPSLHVRKQKALEAELDAQHLSETFDNIDNLSPKASHRNKQRHKQNIYGEYVLDSSRHDDGVCRTESFNTGNMTVLSPYLNSTVLPGSASSSRGNIENCLSEKDRSLDRDRAVGLNAYHPATENSGNSSKRIGMQISTAAAQIAKVMEEVTSMHIPQEDRSSGSTSEMHCLTEDRNTTRRAATAHTHSNTYFPKSENSSRPCPVPYTKMEYKRASNDSLNSVSSSDGYGKRGQMKPSIESYSEDDESKFCSYGQYPADLAHKIHSANHMDDNDGELDTPINYSLKYSDEQLNSGRQSPSQNERWARPKHIIDDEMKQNDQRQSRSQSATYPVYTESGDDKHMKYQSPFGQQDCVPSFRSRGSNGSDQNRVGSTLGINQKVNQSLCQVDDYDDDKPTNYSERYSEEEQHEEEDRPTNYSIKYNEEEHQVDQPIDYSLKYSTEVPPSSQKPSFTFSKTSSVQSTKTDHISSSSGNTSAPSAGSKRQNQLHPSSAQSRGGHAQKTASCKTPSINQETIQTYCVEDTPICFSRCSSLSSLSSAEDEIGRDQSTRVTDTNATLQISELKENSGALSAEAAVSEITSTSQHIRTKSSRLPTSSLSPSESSRHKAVEFSSGAKSPSKSGAQTPKSPPEHYVQETPLMFSRCTSVSSLDSFESRSIASSVQSEPCSGMVSGIISPSDLPDSPGQTMPPSRSKTPPPAQGVQVKRDVTKGKVPTAEKREPGPRQAAVNAAVQRVQVLPDADTLLHFATESTPDGFSCSSSLSALSLDEPFIQKDVELRIMPPVHENEHGNEAEPEQSDETKDNQENKAEKPSEAEKDILDDSDDDDIEILEECIISAMPTKSSRKAKKPSQASAPKIPPPVARKPSQLPVYKLLPSQSRLQSQKHVSFTPGDDMPRVYCVEGTPINFSTATSLSDLTIESPPNELANVDSVGAGAESGEFEKRDTIPTEGRSTDDTQRAKSITVTGPGLDDDKTEEGDILAECINSAMPKGKSHKPFRVKKIMDQIQQASTSLNNKNQPEGEKKKPTSPVKPVPQNSEYRARVRKNTESKSQINNERSYPENRDAKKQNLKNNSRDFNDKLPNNEERVRGSFTFDSPHHYTPIEGTPYCFSRNDSLSSLDFDDDDVDLSREKAELRKGKEAKEVETKDCPNVEQPSGQQPSNRTQVCQKHPTSRSQSKTFCQPSKDIPDRGAATDEKMQNFAIENTPVCFSRNSSLSSLSDIDQENNNNKEGEPVKRTEAPDSQIESSRPQTSGYAPKSFHVEDTPVCFSRNSSLSSLSIDSEDDLLQECISSAMPKKKKPSRIKSESEKSNSRNIGGMLAEDLTLDLREIQRPDSEHGFSPDSENFDWKAIQEGANSIVSSLHQAAAAASLSRQASSDSDSILSLKSGISLGSPFHLTPDQEEKPFTSNKGPRILKPGEKSTLESKKVESESKGIKGGKRVYKSIITGKARSNSEVSSQIKQPQQTSVPSISRGRTMIHIPGVRNSSSSTSPVSKKGPPFKNTNSKSPSEGQSSASSPRGVKSSVKPEPAPVTRQLSGLNQGGSSKGPSRSGSRDSTPSRPQQQPLSRPLQSPGRNSISPGRNGISPPNKLSQLPRTSSPSTASTKSSSSGRMSYTSPGRQMSQQNLTKQTALTKNTSSIPRSESASKGLNQILGSGASNKKTDLSRMSSAKSSGSESDRSERPVLVRQSTFIKEAPSPTLRRKLEESASFESLSPSRPDSPTRSQLQTPVLSPSLPDMSLSTHSTAQTSGWRKLPPNLSPSVEYDGRPAKRHDIARSHSESPSRLPINRSGTWKREHSKHSSSLPRVSTWRRTGSSSSILSASSESSEKAKSEDEKQHGSSLSGQKQSKESQAPAKGTWRKIKENEIPQIMNDPQHPSSSATSSSDSKTLIYQMAPAVSKTEDVWVRIEDCPINNPRSGRSPTGNTPPVIDSVSEKGVVNGKDSKEIQEKQNPGNGSVPVRTIGLENRLNSFFQMDSPDKKGNETKPLQTNPVPAPENNESTVSERTPFSSSSSSKHNSPIGAVAARVTPFNYNPSRRKSSVDNSSARPSQIPTPVNNSTKKRDSKSENTDSSGTQSPKRHSGSYLVTSV", "length": 2853, "header": "tr|A0A1D5PC88-1|A0A1D5PC88_CHICK Isoform 1 of APC regulator of WNT signaling pathway OS=Gallus gallus OX=9031 GN=APC PE=3 SV=1 CANONICAL=A0A1D5PC88-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PC88-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PC88/entry#A0A1D5PC88-1", "sequence": { "sequence": "MAAASYDQLLKQVEALKMENSNLRQELEDNSNHLTKLETEASNMKMVDPAGICTYLEEVLKQLQGSIEDEAIASSGQIDLLERLKELNLESTSFPGVKLRQKVSVRSYGSREGSVSSRSGECSPVPMGSFPRRGFMNGSRESTGYLEELEKERSLLLAELEKEEKEKDWYYAQLQNLTKRIDSLPLTENFSLQTDMTRRQLEYEARQIRAAMEEQLGTCQDMEKRAQVRVARIQQIEKDILRIRQLLQSQAAEAERAPQGKHDAASHDTERQSEGQGAPEISMSTSNTGQGSAARMDHETASVMSSSNNYSVPRRLTSHLGTKVEMVYSLLSMLGTHDKDDMSRTLLAMSSSQDSCIAMRQSGCLPLLIQLLHGNDKDSVLLGNSRGSKEARARASAALHNIIHSQPDDKRGRREIRVLHLLEQIRAYCETCWEWQEAHEQGMDQDKNPMPAPVDHQICPAVCVLMKLSFDEEHRHAMNELGGLQAIAELLQVDCEMYGLTNDHYSVTLRRYAGMALTNLTFGDVANKATLCSMKGCMRALVAQLKSESEDLQQVIASVLRNLSWRADVNSKKTLREVGSVKALMECALEVKKESTLKSVLSALWNLSAHCTENKADICAVDGALAFLVGTLTYRSQTNTLAIIESGGGILRNVSSLIATNEDHRQILRENSCLQTLLQHLKSHSLTIVSNACGTLWNLSARNAKDQEALWDMGAVSMLKNLIHSKHKMIAMGSAAALRNLMANRPAKYKDTNIMSPGSSLPSLHVRKQKALEAELDAQHLSETFDNIDNLSPKASHRNKQRHKQNIYGEYVLDSSRHDDGVCRTESFNTGNMTVLSPYLNSTVLPGSASSSRGNIENCLSEKDRSLDRDRAVGLNAYHPATENSGNSSKRIGMQISTAAAQIAKVMEEVTSMHIPQEDRSSGSTSEMHCLTEDRNTTRRAATAHTHSNTYFPKSENSSRPCPVPYTKMEYKRASNDSLNSVSSSDGYGKRGQMKPSIESYSEDDESKFCSYGQYPADLAHKIHSANHMDDNDGELDTPINYSLKYSDEQLNSGRQSPSQNERWARPKHIIDDEMKQNDQRQSRSQSATYPVYTESGDDKHMKYQSPFGQQDCVPSFRSRGSNGSDQNRVGSTLGINQKVNQSLCQVDDYDDDKPTNYSERYSEEEQHEEEDRPTNYSIKYNEEEHQVDQPIDYSLKYSTEVPPSSQKPSFTFSKTSSVQSTKTDHISSSSGNTSAPSAGSKRQNQLHPSSAQSRGGHAQKTASCKTPSINQETIQTYCVEDTPICFSRCSSLSSLSSAEDEIGRDQSTRVTDTNATLQISELKENSGALSAEAAVSEITSTSQHIRTKSSRLPTSSLSPSESSRHKAVEFSSGAKSPSKSGAQTPKSPPEHYVQETPLMFSRCTSVSSLDSFESRSIASSVQSEPCSGMVSGIISPSDLPDSPGQTMPPSRSKTPPPAQGVQVKRDVTKGKVPTAEKREPGPRQAAVNAAVQRVQVLPDADTLLHFATESTPDGFSCSSSLSALSLDEPFIQKDVELRIMPPVHENEHGNEAEPEQSDETKDNQENKAEKPSEAEKDILDDSDDDDIEILEECIISAMPTKSSRKAKKPSQASAPKIPPPVARKPSQLPVYKLLPSQSRLQSQKHVSFTPGDDMPRVYCVEGTPINFSTATSLSDLTIESPPNELANVDSVGAGAESGEFEKRDTIPTEGRSTDDTQRAKSITVTGPGLDDDKTEEGDILAECINSAMPKGKSHKPFRVKKIMDQIQQASTSLNNKNQPEGEKKKPTSPVKPVPQNSEYRARVRKNTESKSQINNERSYPENRDAKKQNLKNNSRDFNDKLPNNEERVRGSFTFDSPHHYTPIEGTPYCFSRNDSLSSLDFDDDDVDLSREKAELRKGKEAKEVETKDCPNVEQPSGQQPSNRTQVCQKHPTSRSQSKTFCQPSKDIPDRGAATDEKMQNFAIENTPVCFSRNSSLSSLSDIDQENNNNKEGEPVKRTEAPDSQIESSRPQTSGYAPKSFHVEDTPVCFSRNSSLSSLSIDSEDDLLQECISSAMPKKKKPSRIKSESEKSNSRNIGGMLAEDLTLDLREIQRPDSEHGFSPDSENFDWKAIQEGANSIVSSLHQAAAAASLSRQASSDSDSILSLKSGISLGSPFHLTPDQEEKPFTSNKGPRILKPGEKSTLESKKVESESKGIKGGKRVYKSIITGKARSNSEVSSQIKQPQQTSVPSISRGRTMIHIPGVRNSSSSTSPVSKKGPPFKNTNSKSPSEGQSSASSPRGVKSSVKPEPAPVTRQLSGLNQGGSSKGPSRSGSRDSTPSRPQQQPLSRPLQSPGRNSISPGRNGISPPNKLSQLPRTSSPSTASTKSSSSGRMSYTSPGRQMSQQNLTKQTALTKNTSSIPRSESASKGLNQILGSGASNKKTDLSRMSSAKSSGSESDRSERPVLVRQSTFIKEAPSPTLRRKLEESASFESLSPSRPDSPTRSQLQTPVLSPSLPDMSLSTHSTAQTSGWRKLPPNLSPSVEYDGRPAKRHDIARSHSESPSRLPINRSGTWKREHSKHSSSLPRVSTWRRTGSSSSILSASSESSEKAKSEDEKQHGSSLSGQKQSKESQAPAKGTWRKIKENEIPQIMNDPQHPSSSATSSSDSKTLIYQMAPAVSKTEDVWVRIEDCPINNPRSGRSPTGNTPPVIDSVSEKGVVNGKDSKEIQEKQNPGNGSVPVRTIGLENRLNSFFQMDSPDKKGNETKPLQTNPVPAPENNESTVSERTPFSSSSSSKHNSPIGAVAARVTPFNYNPSRRKSSVDNSSARPSQIPTPVNNSTKKRDSKSENTDSSGTQSPKRHSGSYLVTSV", "length": 2853, "header": "tr|A0A1D5PC88-1|A0A1D5PC88_CHICK Isoform 1 of APC regulator of WNT signaling pathway OS=Gallus gallus OX=9031 GN=APC PE=3 SV=1 CANONICAL=A0A1D5PC88-1" }, "locus": { "chromosome": "Z", "start_pos": 46752967, "end_pos": 46697505, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010019940.1", "url": "https://www.ensembl.org/id/ENSGALT00010019940.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010011489.1", "url": "https://www.ensembl.org/id/ENSGALP00010011489.1" } ] } }, { "isoform_ac": "A0A8V0XXR0-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PC88/entry#A0A8V0XXR0-1", "sequence": { "sequence": "MFFCRGMTRSLLLAELEKEEKEKDWYYAQLQNLTKRIDSLPLTENFSLQTDMTRRQLEYEARQIRAAMEEQLGTCQDMEKRAQVRVARIQQIEKDILRIRQLLQSQAAEAERAPQGKHDAASHDTERQSEGQGAPEISMSTSNTGQGSAARMDHETASVMSSSNNYSVPRRLTSHLGTKVEMVYSLLSMLGTHDKDDMSRTLLAMSSSQDSCIAMRQSGCLPLLIQLLHGNDKDSVLLGNSRGSKEARARASAALHNIIHSQPDDKRGRREIRVLHLLEQIRAYCETCWEWQEAHEQGMDQDKNPMPAPVDHQICPAVCVLMKLSFDEEHRHAMNELGGLQAIAELLQVDCEMYGLTNDHYSVTLRRYAGMALTNLTFGDVANKATLCSMKGCMRALVAQLKSESEDLQQVIASVLRNLSWRADVNSKKTLREVGSVKALMECALEVKKESTLKSVLSALWNLSAHCTENKADICAVDGALAFLVGTLTYRSQTNTLAIIESGGGILRNVSSLIATNEDHRQILRENSCLQTLLQHLKSHSLTIVSNACGTLWNLSARNAKDQEALWDMGAVSMLKNLIHSKHKMIAMGSAAALRNLMANRPAKYKDTNIMSPGSSLPSLHVRKQKALEAELDAQHLSETFDNIDNLSPKASHRNKQRHKQNIYGEYVLDSSRHDDGVCRTESFNTGNMTVLSPYLNSTVLPGSASSSRGNIENCLSEKDRSLDRDRAVGLNAYHPATENSGNSSKRIGMQISTAAAQIAKVMEEVTSMHIPQEDRSSGSTSEMHCLTEDRNTTRRAATAHTHSNTYFPKSENSSRPCPVPYTKMEYKRASNDSLNSVSSSDGYGKRGQMKPSIESYSEDDESKFCSYGQYPADLAHKIHSANHMDDNDGELDTPINYSLKYSDEQLNSGRQSPSQNERWARPKHIIDDEMKQNDQRQSRSQSATYPVYTESGDDKHMKYQSPFGQQDCVPSFRSRGSNGSDQNRVGSTLGINQKVNQSLCQVDDYDDDKPTNYSERYSEEEQHEEEDRPTNYSIKYNEEEHQVDQPIDYSLKYSTEVPPSSQKPSFTFSKTSSVQSTKTDHISSSSGNTSAPSAGSKRQNQLHPSSAQSRGGHAQKTASCKTPSINQETIQTYCVEDTPICFSRCSSLSSLSSAEDEIGRDQSTRVTDTNATLQISELKENSGALSAEAAVSEITSTSQHIRTKSSRLPTSSLSPSESSRHKAVEFSSGAKSPSKSGAQTPKSPPEHYVQETPLMFSRCTSVSSLDSFESRSIASSVQSEPCSGMVSGIISPSDLPDSPGQTMPPSRSKTPPPAQGVQVKRDVTKGKVPTAEKREPGPRQAAVNAAVQRVQVLPDADTLLHFATESTPDGFSCSSSLSALSLDEPFIQKDVELRIMPPVHENEHGNEAEPEQSDETKDNQENKAEKPSEAEKDILDDSDDDDIEILEECIISAMPTKSSRKAKKPSQASAPKIPPPVARKPSQLPVYKLLPSQSRLQSQKHVSFTPGDDMPRVYCVEGTPINFSTATSLSDLTIESPPNELANVDSVGAGAESGEFEKRDTIPTEGRSTDDTQRAKSITVTGPGLDDDKTEEGDILAECINSAMPKGKSHKPFRVKKIMDQIQQASTSLNNKNQPEGEKKKPTSPVKPVPQNSEYRARVRKNTESKSQINNERSYPENRDAKKQNLKNNSRDFNDKLPNNEERVRGSFTFDSPHHYTPIEGTPYCFSRNDSLSSLDFDDDDVDLSREKAELRKGKEAKEVETKDCPNVEQPSGQQPSNRTQVCQKHPTSRSQSKTFCQPSKDIPDRGAATDEKMQNFAIENTPVCFSRNSSLSSLSDIDQENNNNKEGEPVKRTEAPDSQIESSRPQTSGYAPKSFHVEDTPVCFSRNSSLSSLSIDSEDDLLQECISSAMPKKKKPSRIKSESEKSNSRNIGGMLAEDLTLDLREIQRPDSEHGFSPDSENFDWKAIQEGANSIVSSLHQAAAAASLSRQASSDSDSILSLKSGISLGSPFHLTPDQEEKPFTSNKGPRILKPGEKSTLESKKVESESKGIKGGKRVYKSIITGKARSNSEVSSQIKQPQQTSVPSISRGRTMIHIPGVRNSSSSTSPVSKKGPPFKNTNSKSPSEGQSSASSPRGVKSSVKPEPAPVTRQLSGLNQGGSSKGPSRSGSRDSTPSRPQQQPLSRPLQSPGRNSISPGRNGISPPNKLSQLPRTSSPSTASTKSSSSGRMSYTSPGRQMSQQNLTKQTALTKNTSSIPRSESASKGLNQILGSGASNKKTDLSRMSSAKSSGSESDRSERPVLVRQSTFIKEAPSPTLRRKLEESASFESLSPSRPDSPTRSQLQTPVLSPSLPDMSLSTHSTAQTSGWRKLPPNLSPSVEYDGRPAKRHDIARSHSESPSRLPINRSGTWKREHSKHSSSLPRVSTWRRTGSSSSILSASSESSEKAKSEDEKQHGSSLSGQKQSKESQAPAKGTWRKIKENEIPQIMNDPQHPSSSATSSSDSKTLIYQMAPAVSKTEDVWVRIEDCPINNPRSGRSPTGNTPPVIDSVSEKGVVNGKDSKEIQEKQNPGNGSVPVRTIGLENRLNSFFQMDSPDKKGNETKPLQTNPVPAPENNESTVSERTPFSSSSSSKHNSPIGAVAARVTPFNYNPSRRKSSVDNSSARPSQIPTPVNNSTKKRDSKSENTDSSGTQSPKRHSGSYLVTSV", "length": 2709, "header": "tr|A0A8V0XXR0-1|A0A8V0XXR0_CHICK Computationally mapped isoform of APC regulator of WNT signaling pathway OS=Gallus gallus OX=9031 GN=APC PE=3 SV=1 CANONICAL=A0A1D5PC88-1" }, "locus": { "chromosome": "Z", "start_pos": 46731022, "end_pos": 46697505, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010019934.1", "url": "https://www.ensembl.org/id/ENSGALT00010019934.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010011482.1", "url": "https://www.ensembl.org/id/ENSGALP00010011482.1" } ] } }, { "isoform_ac": "A0A8V0XZP1-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PC88/entry#A0A8V0XZP1-1", "sequence": { "sequence": "MAAASYDQLLKQVEALKMENSNLRQELEDNSNHLTKLETEASNMKEVLKQLQGSIEDEAIASSGQIDLLERLKELNLESTSFPGVKLRQKVSVRSYGSREGSVSSRSGECSPVPMGSFPRRGFMNGSRESTGYLEELEKERSLLLAELEKEEKEKDWYYAQLQNLTKRIDSLPLTENFSLQTDMTRRQLEYEARQIRAAMEEQLGTCQDMEKRAQVRVARIQQIEKDILRIRQLLQSQAAEAERAPQGKHDAASHDTERQSEGQGAPEISMSTSNTGQGSAARMDHETASVMSSSNNYSVPRRLTSHLGTKVEMVYSLLSMLGTHDKDDMSRTLLAMSSSQDSCIAMRQSGCLPLLIQLLHGNDKDSVLLGNSRGSKEARARASAALHNIIHSQPDDKRGRREIRVLHLLEQIRAYCETCWEWQEAHEQGMDQDKNPMPAPVDHQICPAVCVLMKLSFDEEHRHAMNELGGLQAIAELLQVDCEMYGLTNDHYSVTLRRYAGMALTNLTFGDVANKATLCSMKGCMRALVAQLKSESEDLQQVIASVLRNLSWRADVNSKKTLREVGSVKALMECALEVKKESTLKSVLSALWNLSAHCTENKADICAVDGALAFLVGTLTYRSQTNTLAIIESGGGILRNVSSLIATNEDHRQILRENSCLQTLLQHLKSHSLTIVSNACGTLWNLSARNAKDQEALWDMGAVSMLKNLIHSKHKMIAMGSAAALRNLMANRPAKYKDTNIMSPGSSLPSLHVRKQKALEAELDAQHLSETFDNIDNLSPKASHRNKQRHKQNIYVLPGSASSSRGNIENCLSEKDRSLDRDRAVGLNAYHPATENSGNSSKRIGMQISTAAAQIAKVMEEVTSMHIPQEDRSSGSTSEMHCLTEDRNTTRRAATAHTHSNTYFPKSENSSRPCPVPYTKMEYKRASNDSLNSVSSSDGYGKRGQMKPSIESYSEDDESKFCSYGQYPADLAHKIHSANHMDDNDGELDTPINYSLKYSDEQLNSGRQSPSQNERWARPKHIIDDEMKQNDQRQSRSQSATYPVYTESGDDKHMKYQSPFGQQDCVPSFRSRGSNGSDQNRVGSTLGINQKVNQSLCQVDDYDDDKPTNYSERYSEEEQHEEEDRPTNYSIKYNEEEHQVDQPIDYSLKYSTEVPPSSQKPSFTFSKTSSVQSTKTDHISSSSGNTSAPSAGSKRQNQLHPSSAQSRGGHAQKTASCKTPSINQETIQTYCVEDTPICFSRCSSLSSLSSAEDEIGRDQSTRVTDTNATLQISELKENSGALSAEAAVSEITSTSQHIRTKSSRLPTSSLSPSESSRHKAVEFSSGAKSPSKSGAQTPKSPPEHYVQETPLMFSRCTSVSSLDSFESRSIASSVQSEPCSGMVSGIISPSDLPDSPGQTMPPSRSKTPPPAQGVQVKRDVTKGKVPTAEKREPGPRQAAVNAAVQRVQVLPDADTLLHFATESTPDGFSCSSSLSALSLDEPFIQKDVELRIMPPVHENEHGNEAEPEQSDETKDNQENKAEKPSEAEKDILDDSDDDDIEILEECIISAMPTKSSRKAKKPSQASAPKIPPPVARKPSQLPVYKLLPSQSRLQSQKHVSFTPGDDMPRVYCVEGTPINFSTATSLSDLTIESPPNELANVDSVGAGAESGEFEKRDTIPTEGRSTDDTQRAKSITVTGPGLDDDKTEEGDILAECINSAMPKGKSHKPFRVKKIMDQIQQASTSLNNKNQPEGEKKKPTSPVKPVPQNSEYRARVRKNTESKSQINNERSYPENRDAKKQNLKNNSRDFNDKLPNNEERVRGSFTFDSPHHYTPIEGTPYCFSRNDSLSSLDFDDDDVDLSREKAELRKGKEAKEVETKDCPNVEQPSGQQPSNRTQVCQKHPTSRSQSKTFCQPSKDIPDRGAATDEKMQNFAIENTPVCFSRNSSLSSLSDIDQENNNNKEGEPVKRTEAPDSQIESSRPQTSGYAPKSFHVEDTPVCFSRNSSLSSLSIDSEDDLLQECISSAMPKKKKPSRIKSESEKSNSRNIGGMLAEDLTLDLREIQRPDSEHGFSPDSENFDWKAIQEGANSIVSSLHQAAAAASLSRQASSDSDSILSLKSGISLGSPFHLTPDQEEKPFTSNKGPRILKPGEKSTLESKKVESESKGIKGGKRVYKSIITGKARSNSEVSSQIKQPQQTSVPSISRGRTMIHIPGVRNSSSSTSPVSKKGPPFKNTNSKSPSEGQSSASSPRGVKSSVKPEPAPVTRQLSGLNQGGSSKGPSRSGSRDSTPSRPQQQPLSRPLQSPGRNSISPGRNGISPPNKLSQLPRTSSPSTASTKSSSSGRMSYTSPGRQMSQQNLTKQTALTKNTSSIPRSESASKGLNQILGSGASNKKTDLSRMSSAKSSGSESDRSERPVLVRQSTFIKEAPSPTLRRKLEESASFESLSPSRPDSPTRSQLQTPVLSPSLPDMSLSTHSTAQTSGWRKLPPNLSPSVEYDGRPAKRHDIARSHSESPSRLPINRSGTWKREHSKHSSSLPRVSTWRRTGSSSSILSASSESSEKAKSEDEKQHGSSLSGQKQSKESQAPAKGTWRKIKENEIPQIMNDPQHPSSSATSSSDSKTLIYQMAPAVSKTEDVWVRIEDCPINNPRSGRSPTGNTPPVIDSVSEKGVVNGKDSKEIQEKQNPGNGSVPVRTIGLENRLNSFFQMDSPDKKGNETKPLQTNPVPAPENNESTVSERTPFSSSSSSKHNSPIGAVAARVTPFNYNPSRRKSSVDNSSARPSQIPTPVNNSTKKRDSKSENTDSSGTQSPKRHSGSYLVTSV", "length": 2806, "header": "tr|A0A8V0XZP1-1|A0A8V0XZP1_CHICK Computationally mapped isoform of APC regulator of WNT signaling pathway OS=Gallus gallus OX=9031 GN=APC PE=3 SV=1 CANONICAL=A0A1D5PC88-1" }, "locus": { "chromosome": "Z", "start_pos": 46752967, "end_pos": 46697505, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010019947.1", "url": "https://www.ensembl.org/id/ENSGALT00010019947.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010011495.1", "url": "https://www.ensembl.org/id/ENSGALP00010011495.1" } ] } }, { "isoform_ac": "A0A8V0Y267-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PC88/entry#A0A8V0Y267-1", "sequence": { "sequence": "MVDPAGICTYLEEVLKQLQGSIEDEAIASSGQIDLLERLKELNLESTSFPGVKLRQKVSVRSYGSREGSVSSRSGECSPVPMGSFPRRGFMNGSRESTGYLEELEKERSLLLAELEKEEKEKDWYYAQLQNLTKRIDSLPLTENFSLQTDMTRRQLEYEARQIRAAMEEQLGTCQDMEKRAQVRVARIQQIEKDILRIRQLLQSQAAEAERAPQGKHDAASHDTERQSEGQGAPEISMSTSNTGQGSAARMDHETASVMSSSNNYSVPRRLTSHLGTKVEMVYSLLSMLGTHDKDDMSRTLLAMSSSQDSCIAMRQSGCLPLLIQLLHGNDKDSVLLGNSRGSKEARARASAALHNIIHSQPDDKRGRREIRVLHLLEQIRAYCETCWEWQEAHEQGMDQDKNPMPAPVDHQICPAVCVLMKLSFDEEHRHAMNELGGLQAIAELLQVDCEMYGLTNDHYSVTLRRYAGMALTNLTFGDVANKATLCSMKGCMRALVAQLKSESEDLQQVIASVLRNLSWRADVNSKKTLREVGSVKALMECALEVKKESTLKSVLSALWNLSAHCTENKADICAVDGALAFLVGTLTYRSQTNTLAIIESGGGILRNVSSLIATNEDHRQILRENSCLQTLLQHLKSHSLTIVSNACGTLWNLSARNAKDQEALWDMGAVSMLKNLIHSKHKMIAMGSAAALRNLMANRPAKYKDTNIMSPGSSLPSLHVRKQKALEAELDAQHLSETFDNIDNLSPKASHRNKQRHKQNIYGEYVLDSSRHDDGVCRTESFNTGNMTVLSPYLNSTVLPGSASSSRGNIENCLSEKDRSLDRDRAVGLNAYHPATENSGNSSKRIGMQISTAAAQIAKVMEEVTSMHIPQEDRSSGSTSEMHCLTEDRNTTRRAATAHTHSNTYFPKSENSSRPCPVPYTKMEYKRASNDSLNSVSSSDGYGKRGQMKPSIESYSEDDESKFCSYGQYPADLAHKIHSANHMDDNDGELDTPINYSLKYSDEQLNSGRQSPSQNERWARPKHIIDDEMKQNDQRQSRSQSATYPVYTESGDDKHMKYQSPFGQQDCVPSFRSRGSNGSDQNRVGSTLGINQKVNQSLCQVDDYDDDKPTNYSERYSEEEQHEEEDRPTNYSIKYNEEEHQVDQPIDYSLKYSTEVPPSSQKPSFTFSKTSSVQSTKTDHISSSSGNTSAPSAGSKRQNQLHPSSAQSRGGHAQKTASCKTPSINQETIQTYCVEDTPICFSRCSSLSSLSSAEDEIGRDQSTRVTDTNATLQISELKENSGALSAEAAVSEITSTSQHIRTKSSRLPTSSLSPSESSRHKAVEFSSGAKSPSKSGAQTPKSPPEHYVQETPLMFSRCTSVSSLDSFESRSIASSVQSEPCSGMVSGIISPSDLPDSPGQTMPPSRSKTPPPAQGVQVKRDVTKGKVPTAEKREPGPRQAAVNAAVQRVQVLPDADTLLHFATESTPDGFSCSSSLSALSLDEPFIQKDVELRIMPPVHENEHGNEAEPEQSDETKDNQENKAEKPSEAEKDILDDSDDDDIEILEECIISAMPTKSSRKAKKPSQASAPKIPPPVARKPSQLPVYKLLPSQSRLQSQKHVSFTPGDDMPRVYCVEGTPINFSTATSLSDLTIESPPNELANVDSVGAGAESGEFEKRDTIPTEGRSTDDTQRAKSITVTGPGLDDDKTEEGDILAECINSAMPKGKSHKPFRVKKIMDQIQQASTSLNNKNQPEGEKKKPTSPVKPVPQNSEYRARVRKNTESKSQINNERSYPENRDAKKQNLKNNSRDFNDKLPNNEERVRGSFTFDSPHHYTPIEGTPYCFSRNDSLSSLDFDDDDVDLSREKAELRKGKEAKEVETKDCPNVEQPSGQQPSNRTQVCQKHPTSRSQSKTFCQPSKDIPDRGAATDEKMQNFAIENTPVCFSRNSSLSSLSDIDQENNNNKEGEPVKRTEAPDSQIESSRPQTSGYAPKSFHVEDTPVCFSRNSSLSSLSIDSEDDLLQECISSAMPKKKKPSRIKSESEKSNSRNIGGMLAEDLTLDLREIQRPDSEHGFSPDSENFDWKAIQEGANSIVSSLHQAAAAASLSRQASSDSDSILSLKSGISLGSPFHLTPDQEEKPFTSNKGPRILKPGEKSTLESKKVESESKGIKGGKRVYKSIITGKARSNSEVSSQIKQPQQTSVPSISRGRTMIHIPGVRNSSSSTSPVSKKGPPFKNTNSKSPSEGQSSASSPRGVKSSVKPEPAPVTRQLSGLNQGGSSKGPSRSGSRDSTPSRPQQQPLSRPLQSPGRNSISPGRNGISPPNKLSQLPRTSSPSTASTKSSSSGRMSYTSPGRQMSQQNLTKQTALTKNTSSIPRSESASKGLNQILGSGASNKKTDLSRMSSAKSSGSESDRSERPVLVRQSTFIKEAPSPTLRRKLEESASFESLSPSRPDSPTRSQLQTPVLSPSLPDMSLSTHSTAQTSGWRKLPPNLSPSVEYDGRPAKRHDIARSHSESPSRLPINRSGTWKREHSKHSSSLPRVSTWRRTGSSSSILSASSESSEKAKSEDEKQHGSSLSGQKQSKESQAPAKGTWRKIKENEIPQIMNDPQHPSSSATSSSDSKTLIYQMAPAVSKTEDVWVRIEDCPINNPRSGRSPTGNTPPVIDSVSEKGVVNGKDSKEIQEKQNPGNGSVPVRTIGLENRLNSFFQMDSPDKKGNETKPLQTNPVPAPENNESTVSERTPFSSSSSSKHNSPIGAVAARVTPFNYNPSRRKSSVDNSSARPSQIPTPVNNSTKKRDSKSENTDSSGTQSPKRHSGSYLVTSV", "length": 2808, "header": "tr|A0A8V0Y267-1|A0A8V0Y267_CHICK Computationally mapped isoform of APC regulator of WNT signaling pathway OS=Gallus gallus OX=9031 GN=APC PE=3 SV=1 CANONICAL=A0A1D5PC88-1" }, "locus": { "chromosome": "Z", "start_pos": 46741485, "end_pos": 46697505, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010019959.1", "url": "https://www.ensembl.org/id/ENSGALT00010019959.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010011507.1", "url": "https://www.ensembl.org/id/ENSGALP00010011507.1" } ] } }, { "isoform_ac": "A0A8V0Y647-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PC88/entry#A0A8V0Y647-1", "sequence": { "sequence": "MAAASYDQLLKQVEALKMENSNLRQELEDNSNHLTKLETEASNMKEVLKQLQGSIEDEAIASSGQIDLLERLKELNLESTSFPGVKLRQKVSVRSYGSREGSVSSRSGECSPVPMGSFPRRGFMNGSRESTGYLEELEKERSLLLAELEKEEKEKDWYYAQLQNLTKRIDSLPLTENFSLQTDMTRRQLEYEARQIRAAMEEQLGTCQDMEKRAQVRVARIQQIEKDILRIRQLLQSQAAEAERAPQGKHDAASHDTERQSEGQGAPEISMSTSNTGQGSAARMDHETASVMSSSNNYSVPRRLTSHLGTKVTEDYKPQVEMVYSLLSMLGTHDKDDMSRTLLAMSSSQDSCIAMRQSGCLPLLIQLLHGNDKDSVLLGNSRGSKEARARASAALHNIIHSQPDDKRGRREIRVLHLLEQIRAYCETCWEWQEAHEQGMDQDKNPMPAPVDHQICPAVCVLMKLSFDEEHRHAMNELGGLQAIAELLQVDCEMYGLTNDHYSVTLRRYAGMALTNLTFGDVANKATLCSMKGCMRALVAQLKSESEDLQQVIASVLRNLSWRADVNSKKTLREVGSVKALMECALEVKKESTLKSVLSALWNLSAHCTENKADICAVDGALAFLVGTLTYRSQTNTLAIIESGGGILRNVSSLIATNEDHRQILRENSCLQTLLQHLKSHSLTIVSNACGTLWNLSARNAKDQEALWDMGAVSMLKNLIHSKHKMIAMGSAAALRNLMANRPAKYKDTNIMSPGSSLPSLHVRKQKALEAELDAQHLSETFDNIDNLSPKASHRNKQRHKQNIYGEYVLDSSRHDDGVCRTESFNTGNMTVLSPYLNSTVLPGSASSSRGNIENCLSEKDRSLDRDRAVGLNAYHPATENSGNSSKRIGMQISTAAAQIAKVMEEVTSMHIPQEDRSSGSTSEMHCLTEDRNTTRRAATAHTHSNTYFPKSENSSRPCPVPYTKMEYKRASNDSLNSVSSSDGYGKRGQMKPSIESYSEDDESKFCSYGQYPADLAHKIHSANHMDDNDGELDTPINYSLKYSDEQLNSGRQSPSQNERWARPKHIIDDEMKQNDQRQSRSQSATYPVYTESGDDKHMKYQSPFGQQDCVPSFRSRGSNGSDQNRVGSTLGINQKVNQSLCQVDDYDDDKPTNYSERYSEEEQHEEEDRPTNYSIKYNEEEHQVDQPIDYSLKYSTEVPPSSQKPSFTFSKTSSVQSTKTDHISSSSGNTSAPSAGSKRQNQLHPSSAQSRGGHAQKTASCKTPSINQETIQTYCVEDTPICFSRCSSLSSLSSAEDEIGRDQSTRVTDTNATLQISELKENSGALSAEAAVSEITSTSQHIRTKSSRLPTSSLSPSESSRHKAVEFSSGAKSPSKSGAQTPKSPPEHYVQETPLMFSRCTSVSSLDSFESRSIASSVQSEPCSGMVSGIISPSDLPDSPGQTMPPSRSKTPPPAQGVQVKRDVTKGKVPTAEKREPGPRQAAVNAAVQRVQVLPDADTLLHFATESTPDGFSCSSSLSALSLDEPFIQKDVELRIMPPVHENEHGNEAEPEQSDETKDNQENKAEKPSEAEKDILDDSDDDDIEILEECIISAMPTKSSRKAKKPSQASAPKIPPPVARKPSQLPVYKLLPSQSRLQSQKHVSFTPGDDMPRVYCVEGTPINFSTATSLSDLTIESPPNELANVDSVGAGAESGEFEKRDTIPTEGRSTDDTQRAKSITVTGPGLDDDKTEEGDILAECINSAMPKGKSHKPFRVKKIMDQIQQASTSLNNKNQPEGEKKKPTSPVKPVPQNSEYRARVRKNTESKSQINNERSYPENRDAKKQNLKNNSRDFNDKLPNNEERVRGSFTFDSPHHYTPIEGTPYCFSRNDSLSSLDFDDDDVDLSREKAELRKGKEAKEVETKDCPNVEQPSGQQPSNRTQVCQKHPTSRSQSKTFCQPSKDIPDRGAATDEKMQNFAIENTPVCFSRNSSLSSLSDIDQENNNNKEGEPVKRTEAPDSQIESSRPQTSGYAPKSFHVEDTPVCFSRNSSLSSLSIDSEDDLLQECISSAMPKKKKPSRIKSESEKSNSRNIGGMLAEDLTLDLREIQRPDSEHGFSPDSENFDWKAIQEGANSIVSSLHQAAAAASLSRQASSDSDSILSLKSGISLGSPFHLTPDQEEKPFTSNKGPRILKPGEKSTLESKKVESESKGIKGGKRVYKSIITGKARSNSEVSSQIKQPQQTSVPSISRGRTMIHIPGVRNSSSSTSPVSKKGPPFKNTNSKSPSEGQSSASSPRGVKSSVKPEPAPVTRQLSGLNQGGSSKGPSRSGSRDSTPSRPQQQPLSRPLQSPGRNSISPGRNGISPPNKLSQLPRTSSPSTASTKSSSSGRMSYTSPGRQMSQQNLTKQTALTKNTSSIPRSESASKGLNQILGSGASNKKTDLSRMSSAKSSGSESDRSERPVLVRQSTFIKEAPSPTLRRKLEESASFESLSPSRPDSPTRSQLQTPVLSPSLPDMSLSTHSTAQTSGWRKLPPNLSPSVEYDGRPAKRHDIARSHSESPSRLPINRSGTWKREHSKHSSSLPRVSTWRRTGSSSSILSASSESSEKAKSEDEKQHGSSLSGQKQSKESQAPAKGTWRKIKENEIPQIMNDPQHPSSSATSSSDSKTLIYQMAPAVSKTEDVWVRIEDCPINNPRSGRSPTGNTPPVIDSVSEKGVVNGKDSKEIQEKQNPGNGSVPVRTIGLENRLNSFFQMDSPDKKGNETKPLQTNPVPAPENNESTVSERTPFSSSSSSKHNSPIGAVAARVTPFNYNPSRRKSSVDNSSARPSQIPTPVNNSTKKRDSKSENTDSSGTQSPKRHSGSYLVTSV", 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:: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052536.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jan 4, 2016 this sequence version replaced XP_004941979.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004941979", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004941979" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PCB1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PCB1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FOXA1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PCB1", "locus": { "chromosome": "5", "start_pos": 36675958, "end_pos": 36680388, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010004888", "url": "https://www.ensembl.org/id/ENSGALG00010004888" } ] } } ], "crossref": [ { "id": "A0A1D5PCB1", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PCB1", "database": "AlphaFoldDB", "categories": [] }, { "id": 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binding", "id": "GO:0019904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019904", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PCB1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PCB1" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PCB1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PCB1" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PCB1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PCB1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PCB1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PCB1" } ], "pmid": "" }, { "name": "fibrillar center", "id": "GO:0001650", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001650", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PCB1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PCB1" } ], "pmid": "" }, { "name": "microvillus", "id": "GO:0005902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005902", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PCB1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PCB1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 11, "go_terms": [ { "name": "chromatin remodeling", "id": "GO:0006338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006338", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PCB1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PCB1" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": 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This record is derived from a genomic sequence (NC_052572.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_420894", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_420894" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PCG4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PCG4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SYT4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PCG4", "locus": { "chromosome": "Z", "start_pos": 3757281, "end_pos": 3746017, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012160", "url": "https://www.ensembl.org/id/ENSGALG00010012160" } ] } } ], "crossref": [ { "id": "A0A1D5PCG4", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PCG4", "database": 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regulation of dendrite extension", "id": "GO:1903861", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903861", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PCG4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PCG4" } ], "pmid": "" }, { "name": "negative regulation of protein secretion", "id": "GO:0050709", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050709", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PCG4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PCG4" } ], "pmid": "" }, { "name": "memory", "id": "GO:0007613", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007613", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PCG4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PCG4" } ], "pmid": "" }, { "name": "regulation of endocytosis", "id": "GO:0030100", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030100", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PCG4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PCG4" } ], "pmid": "" }, { "name": "positive regulation of glutamate secretion", "id": "GO:0014049", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014049", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PCG4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PCG4" } ], "pmid": "" }, { "name": "regulation of dopamine secretion", "id": "GO:0014059", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014059", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PCG4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PCG4" } ], "pmid": "" }, { "name": "vesicle-mediated transport", "id": "GO:0016192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016192", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PCG4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PCG4" } ], "pmid": "" }, { "name": "regulation of calcium ion-dependent exocytosis", "id": "GO:0017158", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017158", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PCG4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PCG4" } ], "pmid": "" }, { "name": "vesicle fusion", "id": "GO:0006906", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006906", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PCG4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PCG4" } ], "pmid": "" }, { "name": "positive regulation of dense core granule exocytosis", "id": "GO:1905415", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905415", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PCG4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PCG4" } ], "pmid": "" }, { "name": "negative regulation of catecholamine secretion", "id": "GO:0033604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033604", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PCG4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PCG4" } ], "pmid": "" }, { "name": "negative regulation of short-term neuronal synaptic plasticity", "id": "GO:0048174", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048174", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PCG4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PCG4" } ], "pmid": "" }, { "name": "negative regulation of retrograde trans-synaptic signaling by neuropeptide", "id": "GO:1905433", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905433", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PCG4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PCG4" } ], "pmid": "" }, { "name": "calcium-dependent activation of synaptic vesicle fusion", "id": "GO:0099502", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099502", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PCG4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PCG4" } ], "pmid": "" }, { "name": "dense core granule cytoskeletal transport", "id": "GO:0099519", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099519", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PCG4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PCG4" } ], "pmid": "" }, { "name": "regulation of trans-synaptic signaling by BDNF, modulating synaptic transmission", "id": "GO:0150035", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0150035", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PCG4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PCG4" } ], "pmid": "" }, { "name": "regulation of postsynaptic dense core vesicle exocytosis", "id": "GO:0150044", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0150044", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PCG4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PCG4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 13, "go_terms": [ { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PCG4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PCG4" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PCG4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PCG4" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PCG4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PCG4" } ], "pmid": "" }, { "name": "axon", "id": "GO:0030424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030424", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PCG4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PCG4" } ], "pmid": "" }, { "name": "dendrite", "id": "GO:0030425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PCG4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PCG4" } ], "pmid": "" }, { "name": "neuronal cell body", "id": "GO:0043025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043025", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PCG4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PCG4" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PCG4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PCG4" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PCG4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PCG4" } ], "pmid": "" }, { "name": "astrocyte projection", "id": "GO:0097449", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097449", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PCG4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PCG4" } ], "pmid": "" }, { "name": "exocytic vesicle", "id": "GO:0070382", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070382", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PCG4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PCG4" } ], "pmid": "" }, { "name": "presynapse", "id": "GO:0098793", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098793", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PCG4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PCG4" } ], "pmid": "" }, { "name": "microvesicle", "id": "GO:1990742", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990742", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PCG4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PCG4" } ], "pmid": "" }, { "name": "neuronal dense core vesicle membrane", "id": "GO:0099012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099012", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PCG4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PCG4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PCG4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PCG4" } ], "pmid": "" }, { "name": "calcium-dependent phospholipid binding", "id": "GO:0005544", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005544", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PCG4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PCG4" } ], "pmid": "" }, { "name": "SNARE binding", "id": "GO:0000149", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000149", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PCG4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PCG4" } ], "pmid": "" }, { "name": "calcium ion sensor activity", "id": "GO:0061891", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061891", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PCG4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PCG4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], 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"https://www.ncbi.nlm.nih.gov/protein/NP_001074361" } ] }, { "name": "chromatin-modifying protein 2a", "type": "synonym", "evidence": [ { "id": "NP_001074361", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074361" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ721103.1, SRR13267649.91914.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000402.1. On Nov 4, 2021 this sequence version replaced NP_001074361.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001074361", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074361" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PCX2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PCX2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CHMP2A", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PCX2", "locus": { "chromosome": "31", "start_pos": 1319023, "end_pos": 1324079, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010004352", "url": "https://www.ensembl.org/id/ENSGALG00010004352" } ] } } ], "crossref": [ { "id": "A0A1D5PCX2", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PCX2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000049517", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000049517", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "776036", "url": "https://www.ncbi.nlm.nih.gov/gene/776036", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR005024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:776036", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:776036", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KMAKMNQ", "url": "https://omabrowser.org/oma/group/KMAKMNQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PCX2", "url": "https://www.orthodb.org/?gene=A0A1D5PCX2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10476", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10476", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03357", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03357", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-1632852", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1632852", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5620971", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5620971", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-917729", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-917729", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9668328", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9668328", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001074361", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074361", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PCX2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PCX2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PCX2-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PCX2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDLLFGRRKTPEELLRQNQRALTRAMRELDRERQKLEAQEKKIIIDIKKMAKQGQMDAVKIMAKDLVRTRRYVKKFITMRANVQAVSLKIQTLKSNNSMAQAMKGVTKAMATMNRQLKLPQIQKIMMEFEKQAEIMDMKEELMNDAIDDAMGDEDDEEESDAVVSQVLDELGLNLTDELATLPPPGGSLAAGEGRAAEAAAALADADADLEERLKNLRRD", "length": 220, "header": "tr|A0A1D5PCX2-1|A0A1D5PCX2_CHICK Isoform 1 of Charged multivesicular body protein 2A OS=Gallus gallus OX=9031 GN=CHMP2A PE=1 SV=2 CANONICAL=A0A1D5PCX2-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PCX2-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PCX2/entry#A0A1D5PCX2-1", "sequence": { "sequence": "MDLLFGRRKTPEELLRQNQRALTRAMRELDRERQKLEAQEKKIIIDIKKMAKQGQMDAVKIMAKDLVRTRRYVKKFITMRANVQAVSLKIQTLKSNNSMAQAMKGVTKAMATMNRQLKLPQIQKIMMEFEKQAEIMDMKEELMNDAIDDAMGDEDDEEESDAVVSQVLDELGLNLTDELATLPPPGGSLAAGEGRAAEAAAALADADADLEERLKNLRRD", "length": 220, "header": "tr|A0A1D5PCX2-1|A0A1D5PCX2_CHICK Isoform 1 of Charged multivesicular body protein 2A OS=Gallus gallus OX=9031 GN=CHMP2A PE=1 SV=2 CANONICAL=A0A1D5PCX2-1" }, "locus": { "chromosome": "31", "start_pos": 1323198, "end_pos": 1320591, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010010159.1", "url": "https://www.ensembl.org/id/ENSGALT00010010159.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010005939.1", "url": "https://www.ensembl.org/id/ENSGALP00010005939.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:776036", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:776036", "resource": "KEGG Pathway" }, { "id": "R-GGA-1632852", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1632852", "resource": "Reactome", "description": "Macroautophagy" }, { "id": "R-GGA-5620971", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5620971", "resource": "Reactome", "description": "Pyroptosis" }, { "id": "R-GGA-917729", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-917729", "resource": "Reactome", "description": "Endosomal Sorting Complex Required For Transport (ESCRT)" }, { "id": "R-GGA-9668328", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9668328", "resource": "Reactome", "description": "Sealing of the nuclear envelope (NE) by ESCRT-III" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I5ZYZ8-1", "protein_name": "NEDD8-conjugating enzyme UBC12", "gene_name": "Ube2m", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "SPPQTEIPELNRRKPNLKLQRGASRGVGWGRCKSCAGAERSRARKNRSGQTTESAEAAGCPRPLPTSASKPRLPRKLSLHRYPAVPCRRKRGCRLLLPPHRSLLAKGASRRESGGPVKAGVRSRSGDSQDPSGRGGGGRGGRSRGGAEDSRVLPSTSEHTRGAKPGQSRTTGAEAGRAVGAEQRGRMIKLFSLKQQKKEEESAGGTKGSSKKASAAQLRIQKDINELNLPKTCDISFSDPDDLLNFKLVICPDEGFYKSGKFVFSFKVGQGYPHDPPKVKCETMVYHPNIDLEGNVCLNILREDWKPVLTINSIIYGLQYLFLEPNPEDPLNKEAAEVLQNNRRLFEQNVQRSMRGGYIGSTYFERCLK", "length": 369 }, "evidence": [ { "id": "A0A1D5PCX2", "url": "https://omabrowser.org/oma/group/A0A1D5PCX2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "I3LSS2-1", "protein_name": "Charged multivesicular body protein 2A", "gene_name": "CHMP2A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDLLFGRRKTPEELLRQNQRALNRAMRELDRERQKLETQEKKIIADIKKMAKQGQMDAVRIMAKDLVRTRRYVRKFVLMRANIQAVSLKIQTLKSNNSMAQAMKGVTKAMGTMNRQLKLPQIQKIMMEFERQAEIMDMKEEMMNDAIDDAMGDEEDEEESDAVVAQVLDELGLSLTDELSNLPSTGGSLSVAASGKKAEAAASALVDADADLEERLKNLRRD", "length": 222 }, "evidence": [ { "id": "A0A1D5PCX2", "url": "https://omabrowser.org/oma/group/A0A1D5PCX2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O43633-1", "protein_name": "Charged multivesicular body protein 2a", "gene_name": "CHMP2A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDLLFGRRKTPEELLRQNQRALNRAMRELDRERQKLETQEKKIIADIKKMAKQGQMDAVRIMAKDLVRTRRYVRKFVLMRANIQAVSLKIQTLKSNNSMAQAMKGVTKAMGTMNRQLKLPQIQKIMMEFERQAEIMDMKEEMMNDAIDDAMGDEEDEEESDAVVSQVLDELGLSLTDELSNLPSTGGSLSVAAGGKKAEAAASALADADADLEERLKNLRRD", "length": 222 }, "evidence": [ { "id": "A0A1D5PCX2", "url": "https://omabrowser.org/oma/group/A0A1D5PCX2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P36108-1", "protein_name": "DOA4-independent degradation protein 4", "gene_name": "DID4", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSLFEWVFGKNVTPQERLKKNQRALERTQRELEREKRKLELQDKKLVSEIKKSAKNGQVAAAKVQAKDLVRTRNYIQKFDNMKAQLQAISLRIQAVRSSDQMTRSMSEATGLLAGMNRTMNLPQLQRISMEFEKQSDLMGQRQEFMDEAIDNVMGDEVDEDEEADEIVNKVLDEIGVDLNSQLQSTPQNLVSNAPIAETAMGIPEPIGAGSEFHGNPDDDLQARLNTLKKQT", "length": 232 }, "evidence": [ { "id": "A0A1D5PCX2", "url": "https://omabrowser.org/oma/group/A0A1D5PCX2/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q54DB1-1", "protein_name": "Charged multivesicular body protein 2a homolog 2", "gene_name": "chmp2a2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MFLFGKQKTPKEVLRENQRNLNKSMREIDRERVALQNQEKKIILDIKKMAKQGQMNSAKIMAKDLVRTRYHIQKFYEMKTQLQAVSLRIQTLQSTQAMAEAMKGVTKAMITMNRQMNLPQFTKIMMEFEQQSDKMDMKEEMMNDTMDQVMEQDGEEEQSQEILNQVLDEIGIDLASQLVDAPTTVGTSVASKHQVNSG", "length": 198 }, "evidence": [ { "id": "A0A1D5PCX2", "url": "https://omabrowser.org/oma/group/A0A1D5PCX2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9DB34-1", "protein_name": "Charged multivesicular body protein 2a", "gene_name": "Chmp2a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDLLFGRRKTPEELLRQNQRALNRAMRELDRERQKLETQEKKIIADIKKMAKQGQMDAVRIMAKDLVRTRRYVRKFVLMRANIQAVSLKIQTLKSNNSMAQAMKGVTKAMGTMNRQLKLPQIQKIMMEFERQAEIMDMKEEMMNDAIDDAMGDEEDEEESDAVVSQVLDELGLSLTDELSNLPSTGGSLSVAAGGKKAEATASALADADADLEERLKNLRRD", "length": 222 }, "evidence": [ { "id": "A0A1D5PCX2", "url": "https://omabrowser.org/oma/group/A0A1D5PCX2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9SKI2-1", "protein_name": "Vacuolar protein sorting-associated protein 2 homolog 1", "gene_name": "VPS2.1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MMNSIFGKRKTPAELLRENKRMLDKSIREIERERQGLQTQEKKLINEIKKTAKQGQMGAVKVMAKDLIRTRHQIEKFYKLKSQLQGVSLRIQTLKSTQAMGEAMKGVTKAMGQMNRQMNLPSLQKIMQEFERQNEKMEMVSEVMGDAIDDALEGDEEEEETEDLVSQVLDEIGIDINQELVNAPSGAVAVPAAKNKVVQAEATGAEDSGGIDSDLQARLDNLRKM", "length": 225 }, "evidence": [ { "id": "A0A1D5PCX2", "url": "https://omabrowser.org/oma/group/A0A1D5PCX2/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9VBI3-1", "protein_name": "Vacuolar protein sorting 2", "gene_name": "Vps2", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDWLFGKKISPDEMLRKNQRALNKAMRDLDRERMKMEQQEKKIIADIKKMAKEGQMDAVKIMAKDLVRTRRYAKKFMLMKANIQAVSLKIQTLKSQNTMAQAMKGVTKAMQNMNRQLNLPQIQKILQDFEKQSEMMDMKEEMINDAIDDAMEDEGDEEETDAVVSQVLDELGLQLGEQLGDLPSASGSLSIAGGAGAQKAQAVAAGGVGGGGAAGGGGASGGGAGGPGAPGGSGASSPMSDADADLQARLDKLRKD", "length": 256 }, "evidence": [ { "id": "A0A1D5PCX2", "url": "https://omabrowser.org/oma/group/A0A1D5PCX2/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 12, "go_terms": [ { "name": "ESCRT III complex", "id": "GO:0000815", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000815", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PCX2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PCX2" } ], "pmid": "" }, { "name": "kinetochore microtubule", "id": "GO:0005828", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005828", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PCX2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PCX2" } ], "pmid": "" }, { "name": "nuclear envelope", "id": "GO:0005635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005635", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PCX2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PCX2" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PCX2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PCX2" } ], "pmid": "" }, { "name": "lysosomal membrane", "id": "GO:0005765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005765", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PCX2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PCX2" } ], "pmid": "" }, { "name": "kinetochore", "id": "GO:0000776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000776", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PCX2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PCX2" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PCX2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PCX2" } ], "pmid": "" }, { "name": "midbody", "id": "GO:0030496", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030496", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PCX2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PCX2" } ], "pmid": "" }, { "name": "membrane coat", "id": "GO:0030117", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030117", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PCX2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PCX2" } ], "pmid": "" }, { "name": "multivesicular body", "id": "GO:0005771", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005771", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PCX2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PCX2" } ], "pmid": "" }, { "name": "multivesicular body membrane", "id": "GO:0032585", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032585", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PCX2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PCX2" } ], "pmid": "" }, { "name": "amphisome membrane", "id": "GO:1904930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904930", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PCX2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PCX2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 21, "go_terms": [ { "name": "plasma membrane repair", "id": "GO:0001778", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001778", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PCX2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PCX2" } ], "pmid": "" }, { "name": "membrane invagination", "id": "GO:0010324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010324", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PCX2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PCX2" } ], "pmid": "" }, { "name": "regulation of centrosome duplication", "id": "GO:0010824", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010824", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PCX2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PCX2" } ], "pmid": "" }, { "name": "nuclear membrane reassembly", "id": "GO:0031468", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031468", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PCX2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PCX2" } ], "pmid": "" }, { "name": "viral budding via host ESCRT complex", "id": "GO:0039702", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0039702", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PCX2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PCX2" } ], "pmid": "" }, { "name": "autophagosome maturation", "id": "GO:0097352", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097352", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PCX2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PCX2" } ], "pmid": "" }, { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PCX2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PCX2" } ], "pmid": "" }, { "name": "protein homooligomerization", "id": "GO:0051260", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051260", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PCX2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PCX2" } ], "pmid": "" }, { "name": "exit from mitosis", "id": "GO:0010458", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010458", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PCX2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PCX2" } ], "pmid": "" }, { "name": "mitotic metaphase chromosome alignment", "id": "GO:0007080", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007080", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PCX2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PCX2" } ], "pmid": "" }, { "name": "protein polymerization", "id": "GO:0051258", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051258", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PCX2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PCX2" } ], "pmid": "" }, { "name": "positive regulation of exosomal secretion", "id": "GO:1903543", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903543", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PCX2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PCX2" } ], "pmid": "" }, { "name": "negative regulation of centriole elongation", "id": "GO:1903723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903723", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PCX2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PCX2" } ], "pmid": "" }, { "name": "late endosome to lysosome transport", "id": "GO:1902774", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902774", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PCX2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PCX2" } ], "pmid": "" }, { "name": "regulation of mitotic spindle assembly", "id": "GO:1901673", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901673", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PCX2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PCX2" } ], "pmid": "" }, { "name": "late endosome to vacuole transport", "id": "GO:0045324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045324", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PCX2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PCX2" } ], "pmid": "" }, { "name": "membrane fission", "id": "GO:0090148", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090148", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PCX2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PCX2" } ], "pmid": "" }, { "name": "endosome transport via multivesicular body sorting pathway", "id": "GO:0032509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032509", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PCX2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PCX2" } ], "pmid": "" }, { "name": "ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway", "id": "GO:0043162", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043162", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PCX2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PCX2" } ], "pmid": "" }, { "name": "viral budding from plasma membrane", "id": "GO:0046761", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046761", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PCX2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PCX2" } ], "pmid": "" }, { "name": "midbody abscission", "id": "GO:0061952", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061952", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PCX2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PCX2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "protein domain specific binding", "id": "GO:0019904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019904", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PCX2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PCX2" } ], "pmid": "" }, { "name": "phosphatidylcholine binding", "id": "GO:0031210", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031210", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PCX2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PCX2" } ], "pmid": "" }, { "name": "membrane bending activity", "id": "GO:0180020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0180020", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PCX2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PCX2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 174, "end_pos": 176, "annotation": "n_glycosylation_sequon" }, { "start_pos": 96, "end_pos": 98, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5PCX2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 220, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5PCX2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5PCX2" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 174, "end_pos": 176 }, { "start_pos": 96, "end_pos": 98 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A1D5PUY5-1", "uniprot_ac": "A0A1D5PUY5", "uniprot_id": "A0A1D5PUY5_CHICK", "mass": { "chemical_mass": 76703.0, "monoisotopic_mass": 76703.0 }, "refseq": { "ac": "XP_015149966", "name": "protein kinase C beta type isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015149966" }, "gene_names": [ { "name": "PRKCB", "type": "recommended", "evidence": [ { "id": "A0A1D5PUY5", "database": 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gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052545.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015149966", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015149966" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PUY5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUY5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PRKCB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUY5", "locus": { "chromosome": "14", "start_pos": 6744479, "end_pos": 6666487, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010018355", "url": "https://www.ensembl.org/id/ENSGALG00010018355" } ] } } ], "crossref": [ { "id": "A0A1D5PUY5", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PUY5", "database": 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"categories": [ "Protein" ] }, { "id": "A0A1D5PUY5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUY5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PUY5-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUY5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAEPPAAPGPEGEEGPVRFARKGALRQKNVHEVKNHKFTARFFKQPTFCSHCTDFIWGFGKQGFQCQVCCFVVHKRCHEFVTFSCPGADKGPASDDPRSKHKFKIHTYSSPTFCDHCGSLLYGLIHQGMKCDTCMMNVHKRCVMNVPSLCGTDHTERRGRIYIRADIEKDVLTVVVRDAKNLVPMDPNGLSDPYVKLKLIPDPKNESKQKTKTIKCSLNPEWNETFRFQLKEADKDRRLSVEIWDWDLTSRNDFMGSLSFGISELQKSGVDGWFKLLSQEEGEYFNVPVPPEGEEGNEELRQKFERAKIGTGSKAADEKTTNAISKFDNNGSRDRMKLSDFNFLMVLGKGSFGKVMLAERKGTDELYAVKILKKDVVIQDDDVECTMVEKRVLALSGKPPFLTQLHSCFQTMDRLYFVMEYVNGGDLMYQIQQVGRFKEPHAVFYAAEIAIGLFFLQSKGIIYRDLKLDNVMLDSEGHIKIADFGMCKENIWDGVTTKTFCGTPDYIAPEIIAYQPYGKSVDWWAFGVLLYEMLAGQAPFEGEDEDELFQSIMEHNVAYPKSMSKEAVAICKGLMTKHPAKRLGCGPEGERDIKEHAFFRYIDWDKLERKEIQPPFKPKACGRNAENFDRFFTRHPPVLTPPDQEVIRNIDQSEFEGFSFFNSEFFKPEAKS", "length": 672, "header": "tr|A0A1D5PUY5-1|A0A1D5PUY5_CHICK Isoform 1 of Protein kinase C OS=Gallus gallus OX=9031 GN=PRKCB PE=1 SV=1 CANONICAL=A0A1D5PUY5-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PCZ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUY5/entry#A0A1D5PCZ1-1", "sequence": { "sequence": 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"MAEPPAAPGPEGEEGPVRFARKGALRQKNVHEVKNHKFTARFFKQPTFCSHCTDFIWGFGKQGFQCQVCCFVVHKRCHEFVTFSCPGADKGPASDDPRSKHKFKIHTYSSPTFCDHCGSLLYGLIHQGMKCDTCMMNVHKRCVMNVPSLCGTDHTERRGRIYIRADIEKDVLTVVVRDAKNLVPMDPNGLSDPYVKLKLIPDPKNESKQKTKTIKCSLNPEWNETFRFQLKEADKDRRLSVEIWDWDLTSRNDFMGSLSFGISELQKSGVDGWFKLLSQEEGEYFNVPVPPEGEEGNEELRQKFERAKIGTGSKAADEKTTNAISKFDNNGSRDRMKLSDFNFLMVLGKGSFGKVMLAERKGTDELYAVKILKKDVVIQDDDVECTMVEKRVLALSGKPPFLTQLHSCFQTMDRLYFVMEYVNGGDLMYQIQQVGRFKEPHAVFYAAEIAIGLFFLQSKGIIYRDLKLDNVMLDSEGHIKIADFGMCKENIWDGVTTKTFCGTPDYIAPEIIAYQPYGKSVDWWAFGVLLYEMLAGQAPFEGEDEDELFQSIMEHNVAYPKSMSKEAVAICKGLMTKHPAKRLGCGPEGERDIKEHAFFRYIDWDKLERKEIQPPFKPKACGRNAENFDRFFTRHPPVLTPPDQEVIRNIDQSEFEGFSFFNSEFFKPEAKS", "length": 672, "header": "tr|A0A1D5PUY5-1|A0A1D5PUY5_CHICK Isoform 1 of Protein kinase C OS=Gallus gallus OX=9031 GN=PRKCB PE=1 SV=1 CANONICAL=A0A1D5PUY5-1" }, "locus": { "chromosome": "14", "start_pos": 6737503, "end_pos": 6666516, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": 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binding", "id": "GO:0042393", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042393", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PUY5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUY5" } ], "pmid": "" }, { "name": "nuclear androgen receptor binding", "id": "GO:0050681", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050681", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PUY5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUY5" } ], "pmid": "" }, { "name": "calcium,diacylglycerol-dependent serine/threonine kinase activity", "id": "GO:0004698", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004698", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PUY5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUY5" } ], "pmid": "" }, { "name": "histone H3T6 kinase activity", "id": "GO:0035403", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035403", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PUY5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUY5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PUY5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUY5" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PUY5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUY5" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PUY5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUY5" } ], "pmid": "" }, { "name": "spectrin", "id": "GO:0008091", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008091", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PUY5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUY5" } ], "pmid": "" }, { "name": "presynaptic cytosol", "id": "GO:0099523", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099523", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PUY5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUY5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 15, "go_terms": [ { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PUY5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUY5" } ], "pmid": "" }, { "name": "positive regulation of canonical NF-kappaB signal transduction", "id": "GO:0043123", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043123", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PUY5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUY5" } ], "pmid": "" }, { "name": "B cell receptor signaling pathway", "id": "GO:0050853", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050853", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PUY5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUY5" } ], "pmid": "" }, { "name": "peptidyl-serine phosphorylation", "id": "GO:0018105", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0018105", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PUY5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUY5" } ], "pmid": "" }, { "name": "negative regulation of D-glucose transmembrane transport", "id": "GO:0010829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010829", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PUY5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUY5" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PUY5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUY5" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": 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"A0A8V0ZKM9-1", "A0A8V0ZWC7-1", "A0A8V1A1Y7-1", "A0A8V1A069-1", "A0A8V0ZI32-1", "A0A8V0ZH91-1", "E1BQV7-1", "A0A8V0ZRX1-1", "A0A8V0ZUU9-1", "A0A8V1A0Y8-1", "A0A8V1A7E9-1", "A0A8V1A7E0-1", "A0A8V1A3T8-1", "A0A8V1A9S5-1", "A0A8V1A7M0-1", "A0A8V1A675-1", "A0A8V1A1P3-1", "A0A8V1ADT4-1", "E1BWT0-1", "A0A8V1ACF6-1", "A0A8V1ADN9-1", "A0A8V1AM12-1", "A0A8V1A4Q4-1", "Q90891-1", "A0A1D5P517-1", "F1NB57-1", "F1NUX4-1", "A0A8V0ZZE4-1", "P05625-1", "P13863-1", "P67962-1", "Q04982-2", "Q0GGW5-1", "Q6XUX0-1", "Q8QGX4-1", "Q9I9E0-1", "Q9IA88-1", "Q5ZJK4-1", "A0A1D5PTJ8-1", "E1C2I2-1", "F1NCX7-1", "F1NKW3-1", "A0A8V1A0W4-1", "A0A8V1A4J8-1", "A0A8V1ACK0-1", "F1NCY7-1", "A0A8V0X6T4-1", "A0A8V0ZFM2-1", "A0A8V0XUM6-1", "A0A8V0XEA3-1", "A0A8V1AIY7-1", "A0A8V0YHH2-1", "A0A3Q2UI52-1", "A0A8V0ZZK5-1", "A0A8V0ZPX2-1", "A0A8V1ACB5-1", "A0A8V0YDH4-1", "A0A8V1AFS4-1", "A0A8V1AH12-1", "A0A8V0YRC9-1", "A0A8V0ZQT5-1", "A0A8V0ZFP1-1", "E1C764-1", "A0A1D5PUY5-1", "F1P4G3-1", "A0A8V0ZMK1-1", "A0A8V0Y2I5-1", "A0A8V0ZLU3-1", "A0A8V0ZNP7-1", "A0A8V0Z2Z3-1", "A0A8V0YNI5-1", "Q90771-1", "A0A8V0X4P0-1", "A0A8V0X7R2-1", "A0A3Q3A664-1", "A0A8V0YGW2-1", "E1C581-1", "A0A8V1AC40-1", "A0A3Q2TUS7-1", "A0A1D5PA08-1", "A0A8V0XFW1-1", "A0A8V0XAH9-1", "A0A8V1A4A1-1", "A0A8V0ZD40-1", "A0A8V0Z6T1-1", "A0A8V1A4V7-1", "E1C093-1", "A0A8V0YZF2-1", "E1BX69-1", "A0A8V0XI18-1", "A0A8V0Y955-1", "A0A1D5PB73-1", "A0A1D5PV76-1", "A0A1D5PX90-1", "A0A1L1RWI9-1", "A0A3Q2TV19-1", "A0A3Q2UF44-1", "A0A8V0X4Q3-1", "A0A8V0Z124-1", "A0A8V0Z6K4-1", "A0A8V1AE45-1", "A0A8V0YZV9-1", "A0A8V0YYZ3-1", "A0A8V0ZUC6-1", "A0A8V0ZUU8-1", "A0A8V1AG70-1", "F1NA68-1", "F1NLR7-1", "A0A8V0Y6K1-1", "A0A8V0XS42-1", "A0A8V0YRN4-1", "A0A8V0YFP8-1", "A0A8V1A7P9-1", "A0A1D5PRN8-1", "A0A3Q3AAD7-1", "A0A3Q2TWZ8-1", "A0A8V0XBZ0-1", "A0A8V0XFX2-1", "A0A8V0YFL1-1", "A0A8V0YTL9-1", "A0A8V0YMB3-1", "A0A8V0X2Y2-1", "A0A8V0XCY6-1", "A0A3Q2UI62-1", "A0A8V0Y241-1", "A0A8V0Z8G2-1", "A0A8V1ABR8-1", "A0A8V1AP60-1", "A0A8V0YZM1-1", "A0A8V0ZB38-1", "A0A8V0Z466-1", "A0A8V0ZA06-1", "A0A8V1AMQ2-1", "A0A8V0ZGY3-1", "A0A8V0ZQJ2-1", "A0A8V0ZYU6-1", "A0A8V1A513-1", "A0A8V0XE48-1", "A0A8V0XQQ4-1", "A0A8V0XKG0-1" ], "evidence": [ { "id": "17989", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/17989" } ] }, { "id": "46608", "name": "", "equation": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A1D5PUY5-1", "Q6U1I9-1", "A0A8V0XNJ2-1", "A0A8V0ZUL0-1", "A0A8V0ZT63-1", "A0A8V1ACW2-1", "A0A8V0Z1X0-1", "A0A8V0YHN2-1", "A0A8V0YMN5-1", "A0A8V0Z807-1", "A0A8V0Z930-1", "A0A8V0YFR6-1", "A0A1D5P0M9-1", "A0A8V0ZBN6-1", "A0A3Q2U9U9-1", "A0A8V0YRC9-1", "A0A8V0YXZ5-1", "A0A8V0ZSP4-1", "A0A8V0ZXQ9-1", "A0A8V0ZZV3-1", "A0A8V1ADF0-1", "A0A8V0ZFT3-1", "A0A8V0ZA45-1", "A0A8V0ZB33-1", "A0A8V0ZD70-1", "A0A8V0Z8T4-1", "R4GIN8-1", "A0A8V0ZK64-1", "A0A8V0ZC16-1", "A0A8V0ZWW1-1", "E1BY69-1", "A0A8V0ZDW9-1", "A0A8V0ZKA2-1", "A0A3Q3B2F1-1", "F1P356-1", "A0A8V1AHA8-1", "Q8QFP8-1", "F1P011-1", "A0A8V0YKK3-1", "A0A1D5NWT4-1", "A0A1D5PMQ7-1", "E1BWA3-1", "F1NVF2-1", "A0A1D5PXN4-1", "A0A3Q2TY19-1", "A0A3Q2U592-1", "A0A8V0XCV5-1", "A0A1D5P8A9-1", "A0A1D5PMG2-1", "A0A8V0X1Q7-1", "A0A8V0Y935-1", "A0A8V0YM96-1", "A0A8V0YF83-1", "A0A8V0YJP9-1", "A0A8V1AKW4-1", "A0A1D5P517-1", "A0A8V0ZSB4-1", "F1NBT0-1", "P18652-1", "P21868-1", "P21869-1", "P53666-1", "P79996-1", "Q5F3W3-1", "Q5ZJS0-1", "Q5ZKN1-1", "Q5ZLL1-1", "A0A8V0XCS0-1", "A0A8V0XNK8-1", "A0A8V0XLV6-1", "A0A8V0XDR5-1", "E1BYH2-1", "F1NB57-1", "E1BQN6-1", "A0A8V0XU71-1", "Q5ZJH6-1", "A0A8V0Y3D1-1", "A0A8V0Y7C3-1", "A0A8V0YCY4-1", "A0A8V0YIV6-1", "A0A8V0YK18-1", "A0A8V0YM22-1", "A0A8V0YTN5-1", "A0A8V0YTP2-1", "Q5F3L1-1", "A0A8V0XU96-1", "E1C6T4-1", "A0A8V0Y3L2-1", "A0A8V0YCY8-1", "A0A8V0Y9Q1-1", "A0A8V0ZD48-1", "A0A8V0ZD60-1", "A0A8V0ZBZ2-1", "A0A8V0Z9J0-1", "A0A8V1ABF3-1", "Q8AYC9-1", "A0A8V0Z927-1", "A0A8V1A2T9-1", "Q5ZKI0-1", "Q7T0B1-1", "P10741-1", "A0A8V1AMK5-1", "P67962-1", "A0A8V0YFH4-1", "E1C848-1", "A0A8V0X8M1-1", "E1BW33-1", "A0A8V0Z283-1", "A0A8V0Z157-1", "A0A3Q2U4X3-1", "A0A8V0XW11-1", "E1BUG0-1", "A0A8V1ABP4-1", "A0A8V1AJA4-1", "A0A8V1AEH4-1", "F1NJH1-1", "A0A3Q2TRY2-1", "A0A8V0X3D6-1", "A0A1D5PD64-1", "A0A8V0XQ97-1", "R4GJB8-1", "A0A8V0X5Z8-1", "A0A8V0XG21-1", "A0A8V0XB58-1", "A0A8V0XMX8-1", "A0A8V0XQS0-1", "A0A8V0XW29-1", "A0A8V0Y074-1", "A0A8V0XXB8-1", "A0A8V0XQ14-1", "A0A8V0XI18-1", "A0A8V0XMT1-1", "A0A8V0Y457-1", "A0A8V0Y823-1", "A0A8V0Y4L8-1", "A0A8V0XND6-1", "A0A8V0Y8X9-1", "A0A8V0YZ74-1", "A0A8V0YTI1-1", "A0A8V0YLV1-1", "A0A8V0Z2E3-1", "A0A8V0YCV9-1", "A0A8V0YSH3-1", "A0A8V0YYX2-1", "A0A8V0YZY4-1", "Q5ZIU3-1", "A0A8V0YZK0-1", "A0A8V0ZKM9-1", "A0A8V0ZWC7-1", "A0A8V1A1Y7-1", "A0A8V1A069-1", "A0A8V0ZI32-1", "A0A8V0ZH91-1", "E1BQV7-1", "A0A8V0ZRX1-1", "A0A8V0ZUU9-1", "A0A8V1A0Y8-1", "A0A8V1A7E9-1", "A0A8V1A7E0-1", "A0A8V1A3T8-1", "A0A8V1A9S5-1", "A0A8V1A7M0-1", "A0A8V1A675-1", "A0A8V1A1P3-1", "A0A8V1ADT4-1", "E1BWT0-1", "A0A8V1ACF6-1", "A0A8V1ADN9-1", "A0A8V1AM12-1", "A0A8V1A4Q4-1", "Q90891-1", "F1NUX4-1", "A0A8V0ZZE4-1", "P05625-1", "P13863-1", "Q04982-2", "Q0GGW5-1", "Q6XUX0-1", "Q8QGX4-1", "Q9I9E0-1", "Q9IA88-1", "Q5ZJK4-1", "A0A1D5PTJ8-1", "E1C2I2-1", "F1NCX7-1", "F1NKW3-1", "A0A8V1A0W4-1", "A0A8V1A4J8-1", "A0A8V1ACK0-1", "F1NCY7-1", "A0A8V0X6T4-1", "A0A8V0XUM6-1", "A0A8V0XEA3-1", "A0A8V0YHH2-1", "A0A3Q2UI52-1", "A0A8V0ZZK5-1", "A0A8V0ZPX2-1", "A0A8V1ACB5-1", "A0A8V0YDH4-1", "A0A8V1AFS4-1", "A0A8V1AH12-1", "A0A8V0ZQT5-1", "A0A8V0ZFP1-1", "E1C764-1", "F1P4G3-1", "A0A8V0Y2I5-1", "A0A8V0ZLU3-1", "A0A8V0ZNP7-1", "A0A8V0Z2Z3-1", "A0A8V0YNI5-1", "Q90771-1", "A0A8V0X4P0-1", "A0A8V0X7R2-1", "A0A3Q3A664-1", "A0A8V0YGW2-1", "E1C581-1", "A0A8V1AC40-1", "A0A3Q2TUS7-1", "A0A1D5PA08-1", "A0A8V0XFW1-1", "A0A8V0XAH9-1", "A0A8V0ZFM2-1", "A0A8V1A4A1-1", "A0A8V0ZD40-1", "A0A8V0Z6T1-1", "A0A8V1A4V7-1", "A0A8V0YZF2-1", "E1BX69-1", "A0A8V0Y955-1", "A0A1D5PB73-1", "A0A1D5PV76-1", "A0A1D5PX90-1", "A0A1L1RWI9-1", "A0A3Q2TV19-1", "A0A3Q2UF44-1", "A0A8V0X4Q3-1", "A0A8V0Z124-1", "A0A8V0Z6K4-1", "A0A8V1AIY7-1", "A0A8V1AE45-1", "A0A8V0YZV9-1", "A0A8V0YYZ3-1", "A0A8V0ZUC6-1", "A0A8V0ZUU8-1", "A0A8V1AG70-1", "F1NA68-1", "F1NLR7-1", "A0A8V0Y6K1-1", "A0A8V0XS42-1", "A0A8V0YRN4-1", "A0A8V0YFP8-1", "A0A8V1A7P9-1", "A0A1D5PRN8-1", "A0A3Q3AAD7-1", "A0A3Q2TWZ8-1", "A0A8V0XBZ0-1", "A0A8V0XFX2-1", "A0A8V0YFL1-1", "A0A8V0YTL9-1", "A0A8V0YMB3-1", "A0A8V0X2Y2-1", "A0A8V0XCY6-1", "A0A3Q2UI62-1", "A0A8V0Y241-1", "A0A8V0Z8G2-1", "A0A8V1ABR8-1", "A0A8V1AP60-1", "A0A8V0YZM1-1", "A0A8V0ZB38-1", "A0A8V0Z466-1", "A0A8V0ZA06-1", "A0A8V1AMQ2-1", "A0A8V0ZGY3-1", "A0A8V0ZQJ2-1", "A0A8V0ZYU6-1", "A0A8V1A513-1", "A0A8V0XE48-1", "A0A8V0XKG0-1" ], "evidence": [ { "id": "46608", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/46608" } ] }, { "id": "R-GGA-114553", "name": "Activation of conventional Protein Kinase C", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A1D5PUY5-1" ], "evidence": [ { "id": "R-GGA-114553", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-114553" } ] }, { "id": "R-GGA-114683", "name": "Phosphorylation of Platelet Sec-1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-GGA-114682" ], "output_participant_list": [ "R-GGA-114680" ], "enzyme_list": [ "A0A1D5PUY5-1" ], "evidence": [ { "id": "R-GGA-114683", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-114683" } ] }, { "id": "R-GGA-1168373", "name": "PRKCB (Protein kinase C beta, PKC-beta) binds diacylglycerol and phosphatidylserine", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A1D5PUY5-1" ], "evidence": [ { "id": "R-GGA-1168373", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1168373" } ] }, { "id": "R-GGA-1168635", "name": "PRKCB (PKC-beta) phosphorylates CARMA1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A1D5PUY5-1" ], "evidence": [ { "id": "R-GGA-1168635", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1168635" } ] }, { "id": "R-GGA-416639", "name": "Trafficking of GluR2-containing AMPA receptors to extrasynaptic sites", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [ "R-GGA-417017" ], "output_participant_list": [], "enzyme_list": [ "A0A1D5PUY5-1" ], "evidence": [ { "id": "R-GGA-416639", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-416639" } ] }, { "id": "R-GGA-421007", "name": "Endocytosis of Ca impermeable AMPA receptors", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [ "R-GGA-416635" ], "output_participant_list": [], "enzyme_list": [ "A0A1D5PUY5-1" ], "evidence": [ { "id": "R-GGA-421007", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-421007" } ] }, { "id": "R-GGA-5218805", "name": "PKC autophosphorylates", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BQN6-1", "A0A1D5PUY5-1", "A0A1D5PXN4-1" ], "evidence": [ { "id": "R-GGA-5218805", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5218805" } ] }, { "id": "R-GGA-5218813", "name": "DAG and Ca+2 bind to PKC and tether it to membrane", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BQN6-1", "A0A1D5PUY5-1", "A0A1D5PXN4-1" ], "evidence": [ { "id": "R-GGA-5218813", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5218813" } ] }, { "id": "R-GGA-5218821", "name": "PDK1 phosphorylates PKC", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BQN6-1", "A0A8V0ZK64-1", "A0A1D5PUY5-1", "A0A1D5PXN4-1" ], "evidence": [ { "id": "R-GGA-5218821", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5218821" } ] }, { "id": "R-GGA-5218823", "name": "PKC phosphorylates sphingosine kinase 1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [ "R-GGA-391267" ], "output_participant_list": [ "R-GGA-5218716" ], "enzyme_list": [ "E1BQN6-1", "A0A1D5P1F1-1", "A0A1D5PUY5-1", "A0A1D5PXN4-1" ], "evidence": [ { "id": "R-GGA-5218823", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5218823" } ] }, { "id": "R-GGA-5223304", "name": "DAG and Ca+2 bind to PKC and tether it to membrane", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nuclear envelope, nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A1D5PUY5-1" ], "evidence": [ { "id": "R-GGA-5223304", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5223304" } ] }, { "id": "R-GGA-9626817", "name": "PKC phosphorylates NCF1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BQN6-1", "A0A8V0XB51-1", "A0A1D5PUY5-1", "A0A1D5PXN4-1" ], "evidence": [ { "id": "R-GGA-9626817", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9626817" } ] } ], "reaction_participants": [ { "participant_id": "R-GGA-114680", "participant_name": "phospho-STXBP3 [cytosol]", "crossref": [ { "id": "A0A8V0YDV4", "database": "UniProt", "url": "" }, { "id": "ENSGALP00010016673", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALT00010028914", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALG00010012066", "database": "ENSEMBL", "url": "" } ] }, { "participant_id": "R-GGA-114682", "participant_name": "STXBP3 [cytosol]", "crossref": [ { "id": "A0A8V0YDV4", "database": "UniProt", "url": "" }, { "id": "ENSGALG00010012066", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALP00010016673", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALT00010028914", "database": "ENSEMBL", "url": "" } ] }, { "participant_id": "R-GGA-391267", "participant_name": "SPHK1 [cytosol]", "crossref": [ { "id": "A0A1D5P1F1", "database": "UniProt", "url": "" }, { "id": "ENSGALG00010029445", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALP00010043914", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALT00010071223", "database": "ENSEMBL", "url": "" } ] }, { "participant_id": "R-GGA-416635", "participant_name": "AP2A2-3 [endocytic vesicle membrane]", "crossref": [ { "id": "A0A1D5NV94", "database": "UniProt", "url": "" }, { "id": "ENSGALG00010024250", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALP00010036119", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALT00010059180", "database": "ENSEMBL", "url": "" }, { "id": "NP_001383199.1", "database": "RefSeq", "url": "" } ] }, { "participant_id": "R-GGA-417017", "participant_name": "PICK1 [endocytic vesicle membrane]", "crossref": [ { "id": "A0A8V0Y0M6", "database": "UniProt", "url": "" }, { "id": "ENSGALG00010010397", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALP00010014101", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALT00010024857", "database": "ENSEMBL", "url": "" } ] }, { "participant_id": "R-GGA-5218716", "participant_name": "phospho-SPHK1 [cytosol]", "crossref": [ { "id": "ENSGALP00010043914", "database": "ENSEMBL", "url": "" }, { "id": "A0A1D5P1F1", "database": "UniProt", "url": "" }, { "id": "ENSGALT00010071223", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALG00010029445", "database": "ENSEMBL", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5NWT4", "gene_name": "RPS6KA3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5NWT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NWT4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5NWT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NWT4" } ] } ] }, { "uniprot_ac": "A0A1D5P0M9", "gene_name": "MAP3K13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5P0M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P0M9" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A1D5P0M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P0M9" } ] } ] }, { "uniprot_ac": "A0A1D5P1F1", "gene_name": "SPHK1", "activity": [ { "ec_number": "2.7.1.91", "activity": "sphing-4-enine + ATP = sphing-4-enine 1-phosphate + ADP + H(+).", "evidence": [ { "id": "A0A1D5P1F1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1F1" } ] }, { "ec_number": "2.7.1.91", "activity": "", "evidence": [ { "id": "A0A1D5P1F1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1F1" } ] } ] }, { "uniprot_ac": "A0A1D5P517", "gene_name": "PLK3", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5P517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P517" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A1D5P517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P517" } ] } ] }, { "uniprot_ac": "A0A1D5P8A9", "gene_name": "SNRK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5P8A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P8A9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5P8A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P8A9" } ] } ] }, { "uniprot_ac": "A0A1D5PA08", "gene_name": "STK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PA08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PA08" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5PA08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PA08" } ] } ] }, { "uniprot_ac": "A0A1D5PB73", "gene_name": "CASK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PB73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PB73" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5PB73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PB73" } ] } ] }, { "uniprot_ac": "A0A1D5PD64", "gene_name": "MAP2K3", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PD64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PD64" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A1D5PD64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PD64" } ] } ] }, { "uniprot_ac": "A0A1D5PMG2", "gene_name": "DCLK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PMG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMG2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5PMG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMG2" } ] } ] }, { "uniprot_ac": "A0A1D5PMQ7", "gene_name": "STK40", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PMQ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMQ7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5PMQ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMQ7" } ] } ] }, { "uniprot_ac": "A0A1D5PRN8", "gene_name": "DAPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PRN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRN8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5PRN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRN8" } ] } ] }, { "uniprot_ac": "A0A1D5PTJ8", "gene_name": "MAP3K5", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PTJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PTJ8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A1D5PTJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PTJ8" } ] } ] }, { "uniprot_ac": "A0A1D5PUY5", "gene_name": "PRKCB", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PUY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUY5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A1D5PUY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUY5" } ] } ] }, { "uniprot_ac": "A0A1D5PV76", "gene_name": "STK17A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PV76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PV76" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5PV76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PV76" } ] } ] }, { "uniprot_ac": "A0A1D5PX90", "gene_name": "KSR2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PX90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PX90" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5PX90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PX90" } ] } ] }, { "uniprot_ac": "A0A1D5PXN4", "gene_name": "PRKCD", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PXN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PXN4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A1D5PXN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PXN4" } ] } ] }, { "uniprot_ac": "A0A1L1RWI9", "gene_name": "CAMK4", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1L1RWI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RWI9" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A1L1RWI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RWI9" } ] } ] }, { "uniprot_ac": "A0A3Q2TRY2", "gene_name": "TAOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2TRY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TRY2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q2TRY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TRY2" } ] } ] }, { "uniprot_ac": "A0A3Q2TUS7", "gene_name": "TLK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2TUS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TUS7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q2TUS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TUS7" } ] } ] }, { "uniprot_ac": "A0A3Q2TV19", "gene_name": "UHMK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2TV19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TV19" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q2TV19", "database": "UniProtKB", "url": 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"activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XLV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLV6" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0XLV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLV6" } ] } ] }, { "uniprot_ac": "A0A8V0XMT1", "gene_name": "MOS", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XMT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMT1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XMT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMT1" } ] } ] }, { "uniprot_ac": "A0A8V0XMX8", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMX8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMX8" } ] } ] }, { "uniprot_ac": "A0A8V0XND6", "gene_name": "RIOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XND6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XND6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XND6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XND6" } ] } ] }, { "uniprot_ac": "A0A8V0XNJ2", "gene_name": "CDK8", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] } ] }, { "uniprot_ac": "A0A8V0XNK8", "gene_name": "PRKCQ", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XNK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNK8" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0XNK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNK8" } ] } ] }, { "uniprot_ac": "A0A8V0XQ14", "gene_name": "PLK4", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQ14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ14" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A8V0XQ14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ14" } ] } ] }, { "uniprot_ac": "A0A8V0XQ97", "gene_name": "CDK14", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQ97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ97" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0XQ97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ97" } ] } ] }, { "uniprot_ac": "A0A8V0XQQ4", "gene_name": "NME7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQQ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQQ4" } ] } ] }, { "uniprot_ac": "A0A8V0XQS0", "gene_name": "STK24", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQS0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XQS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQS0" } ] } ] }, { "uniprot_ac": "A0A8V0XS42", "gene_name": "MAP3K4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XS42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XS42" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0XS42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XS42" } ] } ] }, { "uniprot_ac": "A0A8V0XU71", "gene_name": "MYO3A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XU71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU71" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XU71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU71" } ] } ] }, { "uniprot_ac": "A0A8V0XU96", "gene_name": "PRKD1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XU96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU96" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0XU96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU96" } ] } ] }, { "uniprot_ac": "A0A8V0XUM6", "gene_name": "LATS1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XUM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XUM6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XUM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XUM6" } ] } ] }, { "uniprot_ac": "A0A8V0XW11", "gene_name": "RPS6KA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XW11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW11" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XW11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW11" } ] } ] }, { "uniprot_ac": "A0A8V0XW29", "gene_name": "CDKL2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XW29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW29" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0XW29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW29" } ] } ] }, { "uniprot_ac": "A0A8V0XXB8", "gene_name": "MAPK15", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XXB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXB8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0XXB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXB8" } ] } ] }, { "uniprot_ac": "A0A8V0Y074", "gene_name": "NEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y074", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y074" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y074", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y074" } ] } ] }, { "uniprot_ac": "A0A8V0Y241", "gene_name": "LOC426385", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y241", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y241" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y241", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y241" } ] } ] }, { "uniprot_ac": "A0A8V0Y2I5", "gene_name": "CDK7", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] } ] }, { "uniprot_ac": "A0A8V0Y3D1", "gene_name": "LRRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y3D1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3D1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": 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"https://www.uniprot.org/uniprotkb/A0A8V0Y457" } ] } ] }, { "uniprot_ac": "A0A8V0Y4L8", "gene_name": "HUNK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y4L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y4L8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y4L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y4L8" } ] } ] }, { "uniprot_ac": "A0A8V0Y6K1", "gene_name": "MAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6K1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6K1" } ] } ] }, { "uniprot_ac": "A0A8V0Y7C3", "gene_name": "DAPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y7C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7C3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y7C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7C3" } ] } ] }, { "uniprot_ac": "A0A8V0Y823", "gene_name": "SRPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y823", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y823" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y823", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y823" } ] } ] }, { "uniprot_ac": "A0A8V0Y8X9", "gene_name": "PRKACA", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y8X9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8X9" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0A8V0Y8X9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8X9" } ] } ] }, { "uniprot_ac": "A0A8V0Y935", "gene_name": "MAST4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y935", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y935" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y935", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y935" } ] } ] }, { "uniprot_ac": "A0A8V0Y955", "gene_name": "PAK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y955", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y955" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y955", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y955" } ] } ] }, { "uniprot_ac": "A0A8V0Y9Q1", "gene_name": "LOC107055388", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y9Q1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9Q1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y9Q1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9Q1" } ] } ] }, { "uniprot_ac": "A0A8V0YCV9", "gene_name": "SIK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YCV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YCV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCV9" } ] } ] }, { "uniprot_ac": "A0A8V0YCY4", "gene_name": "AURKB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YCY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YCY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY4" } ] } ] }, { "uniprot_ac": "A0A8V0YCY8", "gene_name": "RIOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YCY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YCY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY8" } ] } ] }, { "uniprot_ac": "A0A8V0YDH4", "gene_name": "ALPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YDH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDH4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YDH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDH4" } ] } ] }, { "uniprot_ac": "A0A8V0YF83", "gene_name": "WNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YF83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF83" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YF83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF83" } ] } ] }, { "uniprot_ac": "A0A8V0YFH4", "gene_name": "NRK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFH4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YFH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFH4" } ] } ] }, { "uniprot_ac": "A0A8V0YFL1", "gene_name": "CDK19", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0YFL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL1" } ] } ] }, { "uniprot_ac": "A0A8V0YFP8", "gene_name": "RIPK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFP8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YFP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFP8" } ] } ] }, { "uniprot_ac": "A0A8V0YFR6", "gene_name": "TNIK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFR6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YFR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFR6" } ] } ] }, { "uniprot_ac": "A0A8V0YGW2", "gene_name": "STK32B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YGW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGW2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YGW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGW2" } ] } ] }, { "uniprot_ac": "A0A8V0YHH2", "gene_name": "STK38L", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YHH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHH2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YHH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHH2" } ] } ] }, { "uniprot_ac": "A0A8V0YHN2", "gene_name": "RPS6KA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YHN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YHN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN2" } ] } ] }, { "uniprot_ac": "A0A8V0YIV6", "gene_name": "DYRK1A", "activity": [ { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] } ] }, { "uniprot_ac": "A0A8V0YJP9", "gene_name": "RIOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YJP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YJP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP9" } ] } ] }, { "uniprot_ac": "A0A8V0YK18", "gene_name": "CDC42BPB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YK18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YK18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK18" } ] } ] }, { "uniprot_ac": "A0A8V0YKK3", "gene_name": "MAP4K4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKK3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKK3" } ] } ] }, { "uniprot_ac": "A0A8V0YLV1", "gene_name": "MARK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YLV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLV1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YLV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLV1" } ] } ] }, { "uniprot_ac": "A0A8V0YM22", "gene_name": "MYO3AL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YM22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM22" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YM22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM22" } ] } ] }, { "uniprot_ac": "A0A8V0YM96", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YM96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM96" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YM96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM96" } ] } ] }, { "uniprot_ac": "A0A8V0YMB3", "gene_name": "STK32A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMB3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMB3" } ] } ] }, { "uniprot_ac": "A0A8V0YMN5", "gene_name": "BRAF", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YMN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YMN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN5" } ] } ] }, { "uniprot_ac": "A0A8V0YNI5", "gene_name": "NIM1K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YNI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNI5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YNI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNI5" } ] } ] }, { "uniprot_ac": "A0A8V0YRC9", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] } ] }, { "uniprot_ac": "A0A8V0YRN4", "gene_name": "GAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRN4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YRN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRN4" } ] } ] }, { "uniprot_ac": "A0A8V0YSH3", "gene_name": "RPS6KA6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YSH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSH3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YSH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSH3" } ] } ] }, { "uniprot_ac": "A0A8V0YTI1", "gene_name": "TSSK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTI1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTI1" } ] } ] }, { "uniprot_ac": "A0A8V0YTL9", "gene_name": "VRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTL9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTL9" } ] } ] }, { "uniprot_ac": "A0A8V0YTN5", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTN5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTN5" } ] } ] }, { "uniprot_ac": "A0A8V0YTP2", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTP2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTP2" } ] } ] }, { "uniprot_ac": "A0A8V0YXZ5", "gene_name": "CDC42BPA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YXZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXZ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YXZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXZ5" } ] } ] }, { "uniprot_ac": "A0A8V0YYX2", "gene_name": "PAK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YYX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYX2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YYX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYX2" } ] } ] }, { "uniprot_ac": "A0A8V0YYZ3", "gene_name": "SPEG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YYZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYZ3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YYZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYZ3" } ] } ] }, { "uniprot_ac": "A0A8V0YZ74", "gene_name": "MAP2K5", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZ74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZ74" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V0YZ74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZ74" } ] } ] }, { "uniprot_ac": "A0A8V0YZF2", "gene_name": "PAK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZF2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YZF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZF2" } ] } ] }, { "uniprot_ac": "A0A8V0YZK0", "gene_name": "MAP3K6", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZK0" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0YZK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZK0" } ] } ] }, { "uniprot_ac": "A0A8V0YZM1", "gene_name": "MOK", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] }, { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] } ] }, { "uniprot_ac": "A0A8V0YZV9", "gene_name": "ATR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YZV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZV9" } ] } ] }, { "uniprot_ac": "A0A8V0YZY4", "gene_name": "SBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZY4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YZY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZY4" } ] } ] }, { "uniprot_ac": "A0A8V0Z124", "gene_name": "VRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z124", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z124" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z124", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z124" } ] } ] }, { "uniprot_ac": "A0A8V0Z157", "gene_name": "MARK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] } ] }, { "uniprot_ac": "A0A8V0Z1X0", "gene_name": "MAP4K3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z1X0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1X0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z1X0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1X0" } ] } ] }, { "uniprot_ac": "A0A8V0Z283", "gene_name": "MARK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] } ] }, { "uniprot_ac": "A0A8V0Z2E3", "gene_name": "PDIK1L", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z2E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2E3" } ] }, { "ec_number": 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"database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z466" } ] } ] }, { "uniprot_ac": "A0A8V0Z6K4", "gene_name": "PIK3R4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z6K4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6K4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z6K4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6K4" } ] } ] }, { "uniprot_ac": "A0A8V0Z6T1", "gene_name": "ERN2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z6T1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6T1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z6T1", "database": "UniProtKB", "url": 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{ "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z930", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z930" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V0Z930", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z930" } ] } ] }, { "uniprot_ac": "A0A8V0Z9J0", "gene_name": "CIT", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z9J0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9J0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z9J0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9J0" } ] } ] }, { "uniprot_ac": "A0A8V0ZA06", "gene_name": "CDKL1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA06" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0ZA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA06" } ] } ] }, { "uniprot_ac": "A0A8V0ZA45", "gene_name": "MAP4K5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZA45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA45" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZA45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA45" } ] } ] }, { "uniprot_ac": "A0A8V0ZB33", "gene_name": "CAMK2G", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZB33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB33" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V0ZB33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB33" } ] } ] }, { "uniprot_ac": "A0A8V0ZB38", "gene_name": "CIITA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZB38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB38" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZB38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB38" } ] } ] }, { "uniprot_ac": "A0A8V0ZBN6", "gene_name": "MAP2K1", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZBN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBN6" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V0ZBN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBN6" } ] } ] }, { "uniprot_ac": "A0A8V0ZBZ2", "gene_name": "MAP3K9", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZBZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBZ2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0ZBZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBZ2" } ] } ] }, { "uniprot_ac": "A0A8V0ZC16", "gene_name": "KALRN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZC16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC16" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZC16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC16" } ] } ] }, { "uniprot_ac": "A0A8V0ZD40", "gene_name": "CDC2L1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] } ] }, { "uniprot_ac": "A0A8V0ZD48", "gene_name": "PRKCE", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD48" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0ZD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD48" } ] } ] }, { "uniprot_ac": "A0A8V0ZD60", "gene_name": "STK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZD60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD60" } ] } ] }, { "uniprot_ac": "A0A8V0ZD70", "gene_name": "DCLK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD70" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZD70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD70" } ] } ] }, { "uniprot_ac": "A0A8V0ZDW9", "gene_name": "NEK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZDW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDW9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZDW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDW9" } ] } ] }, { "uniprot_ac": "A0A8V0ZFM2", "gene_name": "LMTK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZFM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFM2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZFM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFM2" } ] } ] }, { "uniprot_ac": "A0A8V0ZFP1", "gene_name": "TTBK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZFP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFP1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZFP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFP1" } ] } ] }, { "uniprot_ac": "A0A8V0ZFT3", "gene_name": "LRRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZFT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFT3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZFT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFT3" } ] } ] }, { "uniprot_ac": "A0A8V0ZGY3", "gene_name": "HIPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZGY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGY3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZGY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGY3" } ] } ] }, { "uniprot_ac": "A0A8V0ZH91", "gene_name": "WNK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": 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"https://www.uniprot.org/uniprotkb/A0A8V0ZK64" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZK64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK64" } ] } ] }, { "uniprot_ac": "A0A8V0ZKA2", "gene_name": "EIF2AK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZKA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKA2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZKA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKA2" } ] } ] }, { "uniprot_ac": "A0A8V0ZKM9", "gene_name": "STK36", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZKM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKM9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZKM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKM9" } ] } ] }, { "uniprot_ac": "A0A8V0ZLU3", "gene_name": "TLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZLU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLU3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZLU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLU3" } ] } ] }, { "uniprot_ac": "A0A8V0ZMK1", "gene_name": "PIKFYVE", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] }, { "ec_number": "2.7.1.150", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] }, { "ec_number": "2.7.1.150", "activity": "", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] } ] }, { "uniprot_ac": "A0A8V0ZNP7", "gene_name": "SGK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZNP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNP7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZNP7", "database": 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"ec_number": "2.1.1.-", "activity": "", "evidence": [ { "id": "A0A8V0ZRX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRX1" } ] } ] }, { "uniprot_ac": "A0A8V0ZSB4", "gene_name": "SIK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZSB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSB4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZSB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSB4" } ] } ] }, { "uniprot_ac": "A0A8V0ZSP4", "gene_name": "PKN2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] }, { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] } ] }, { "uniprot_ac": "A0A8V0ZT63", "gene_name": "STK25", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZT63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT63" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZT63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT63" } ] } ] }, { "uniprot_ac": "A0A8V0ZUC6", "gene_name": "PAK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUC6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUC6" } ] } ] }, { "uniprot_ac": "A0A8V0ZUL0", "gene_name": "PASK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUL0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUL0" } ] } ] }, { "uniprot_ac": "A0A8V0ZUU8", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU8" } ] } ] }, { "uniprot_ac": "A0A8V0ZUU9", "gene_name": "MKNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU9" } ] } ] }, { "uniprot_ac": "A0A8V0ZWC7", "gene_name": "EIF2AK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZWC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWC7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZWC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWC7" } ] } ] }, { "uniprot_ac": "A0A8V0ZWW1", "gene_name": "MAP3K12", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZWW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWW1" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0ZWW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWW1" } ] } ] }, { "uniprot_ac": "A0A8V0ZXQ9", "gene_name": "PRKG1", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZXQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXQ9" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0A8V0ZXQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXQ9" } ] } ] }, { "uniprot_ac": "A0A8V0ZYU6", "gene_name": "TNNI3K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZYU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYU6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZYU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYU6" } ] } ] }, { "uniprot_ac": "A0A8V0ZZE4", "gene_name": "OBSCN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZZE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZE4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZZE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZE4" } ] } ] }, { "uniprot_ac": "A0A8V0ZZK5", "gene_name": "STK38", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZZK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZK5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZZK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZK5" } ] } ] }, { "uniprot_ac": "A0A8V0ZZV3", "gene_name": "MYO3B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZZV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZV3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZZV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZV3" } ] } ] }, { "uniprot_ac": "A0A8V1A069", "gene_name": "TESK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A069", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A069" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1A069", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A069" } ] } ] }, { "uniprot_ac": "A0A8V1A0W4", "gene_name": "ULK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A0W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0W4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A0W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0W4" } ] } ] }, { "uniprot_ac": "A0A8V1A0Y8", "gene_name": "MAST2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A0Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Y8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A0Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Y8" } ] } ] }, { "uniprot_ac": "A0A8V1A1P3", "gene_name": "SRPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A1P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1P3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A1P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1P3" } ] } ] }, { "uniprot_ac": "A0A8V1A1Y7", "gene_name": "CDK2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A1Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1Y7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V1A1Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1Y7" } ] } ] }, { "uniprot_ac": "A0A8V1A2T9", "gene_name": "MAP3K14", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A2T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2T9" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V1A2T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2T9" } ] } ] }, { "uniprot_ac": "A0A8V1A3T8", "gene_name": "MAST3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A3T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3T8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A3T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3T8" } ] } ] }, { "uniprot_ac": "A0A8V1A4A1", "gene_name": "CAMKK2", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4A1" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1A4A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4A1" } ] } ] }, { "uniprot_ac": "A0A8V1A4J8", "gene_name": "MAPKAPK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4J8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A4J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4J8" } ] } ] }, { "uniprot_ac": "A0A8V1A4Q4", "gene_name": "MAPK3", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Q4" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1A4Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Q4" } ] } ] }, { "uniprot_ac": "A0A8V1A4V7", "gene_name": "HIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A4V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V7" } ] } ] }, { "uniprot_ac": "A0A8V1A513", "gene_name": "DAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A513" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A513" } ] } ] }, { "uniprot_ac": "A0A8V1A675", "gene_name": "CSNK1G2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A675", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A675" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A675", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A675" } ] } ] }, { "uniprot_ac": "A0A8V1A7E0", "gene_name": "DYRK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1A7E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E0" } ] } ] }, { "uniprot_ac": "A0A8V1A7E9", "gene_name": "SIK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E9" } ] } ] }, { "uniprot_ac": "A0A8V1A7M0", "gene_name": "STK39", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M0" } ] } ] }, { "uniprot_ac": "A0A8V1A7P9", "gene_name": "DCAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] } ] }, { "uniprot_ac": "A0A8V1A9S5", "gene_name": "NUAK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A9S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9S5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A9S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9S5" } ] } ] }, { "uniprot_ac": "A0A8V1ABF3", "gene_name": "PRKAA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] } ] }, { "uniprot_ac": "A0A8V1ABP4", "gene_name": "DSTYK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP4" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1ABP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP4" } ] } ] }, { "uniprot_ac": "A0A8V1ABR8", "gene_name": "CAMK4L", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR8" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1ABR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR8" } ] } ] }, { "uniprot_ac": "A0A8V1AC40", "gene_name": "CDK18", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AC40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC40" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V1AC40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC40" } ] } ] }, { "uniprot_ac": "A0A8V1ACB5", "gene_name": "MAPK13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACB5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1ACB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACB5" } ] } ] }, { "uniprot_ac": "A0A8V1ACF6", "gene_name": "PIM1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF6" } ] } ] }, { "uniprot_ac": "A0A8V1ACK0", "gene_name": "MAPKAPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK0" } ] } ] }, { "uniprot_ac": "A0A8V1ACW2", "gene_name": "WNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACW2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACW2" } ] } ] }, { "uniprot_ac": "A0A8V1ADF0", "gene_name": "MAP2K2", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF0" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V1ADF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF0" } ] } ] }, { "uniprot_ac": "A0A8V1ADN9", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADN9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1ADN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADN9" } ] } ] }, { "uniprot_ac": "A0A8V1ADT4", "gene_name": "MKNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADT4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ADT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADT4" } ] } ] }, { "uniprot_ac": "A0A8V1AE45", "gene_name": "ERN1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AE45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE45" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AE45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE45" } ] } ] }, { "uniprot_ac": "A0A8V1AEH4", "gene_name": "STK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEH4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEH4" } ] } ] }, { "uniprot_ac": "A0A8V1AFS4", "gene_name": "STKLD1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AFS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFS4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AFS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFS4" } ] } ] }, { "uniprot_ac": "A0A8V1AG70", "gene_name": "LOC100857512", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AG70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG70" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AG70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG70" } ] } ] }, { "uniprot_ac": "A0A8V1AH12", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AH12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH12" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AH12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH12" } ] } ] }, { "uniprot_ac": "A0A8V1AHA8", "gene_name": "NEK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AHA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHA8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AHA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHA8" } ] } ] }, { "uniprot_ac": "A0A8V1AIY7", "gene_name": "AATK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AIY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AIY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIY7" } ] } ] }, { "uniprot_ac": "A0A8V1AJA4", "gene_name": "RPS6KB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AJA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJA4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AJA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJA4" } ] } ] }, { "uniprot_ac": "A0A8V1AKW4", "gene_name": "MAP2K4", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AKW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKW4" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V1AKW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKW4" } ] } ] }, { "uniprot_ac": "A0A8V1AM12", "gene_name": "GSG2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AM12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM12" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AM12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM12" } ] } ] }, { "uniprot_ac": "A0A8V1AMK5", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AMK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V1AMK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK5" } ] } ] }, { "uniprot_ac": "A0A8V1AMQ2", "gene_name": "CAMKK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AMQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ2" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1AMQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ2" } ] } ] }, { "uniprot_ac": "A0A8V1AP60", "gene_name": "KSR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AP60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AP60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP60" } ] } ] }, { "uniprot_ac": "E1BQN6", "gene_name": "PRKCZ", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQN6" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1BQN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQN6" } ] } ] }, { "uniprot_ac": "E1BQV7", "gene_name": "SLK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQV7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BQV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQV7" } ] } ] }, { "uniprot_ac": "E1BUG0", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] } ] }, { "uniprot_ac": "E1BW33", "gene_name": "SMG1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BW33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BW33" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BW33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BW33" } ] } ] }, { "uniprot_ac": "E1BWA3", "gene_name": "PRKCI", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BWA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWA3" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1BWA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWA3" } ] } ] }, { "uniprot_ac": "E1BWT0", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BWT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWT0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BWT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWT0" } ] } ] }, { "uniprot_ac": "E1BX69", "gene_name": "EIF2AK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BX69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BX69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BX69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BX69" } ] } ] }, { "uniprot_ac": "E1BY69", "gene_name": "PIM3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BY69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BY69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY69" } ] } ] }, { "uniprot_ac": "E1BYH2", "gene_name": "TAOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BYH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYH2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BYH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYH2" } ] } ] }, { "uniprot_ac": "E1C093", "gene_name": "PIK3CG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] } ] }, { "uniprot_ac": "E1C2I2", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C2I2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2I2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C2I2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2I2" } ] } ] }, { "uniprot_ac": "E1C581", "gene_name": "TBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C581", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C581" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C581", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C581" } ] } ] }, { "uniprot_ac": "E1C6T4", "gene_name": "PRKD3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C6T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C6T4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1C6T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C6T4" } ] } ] }, { "uniprot_ac": "E1C764", "gene_name": "BMP2K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C764", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C764" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C764", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C764" } ] } ] }, { "uniprot_ac": "E1C848", "gene_name": "MAP3K8", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C848", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C848" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1C848", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C848" } ] } ] }, { "uniprot_ac": "F1NA68", "gene_name": "CDK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NA68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NA68" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1NA68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NA68" } ] } ] }, { "uniprot_ac": "F1NB57", "gene_name": "PLK2", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NB57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NB57" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "F1NB57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NB57" } ] } ] }, { "uniprot_ac": "F1NBT0", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NBT0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NBT0" } ] } ] }, { "uniprot_ac": "F1NCX7", "gene_name": "PLK1", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NCX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCX7" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "F1NCX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCX7" } ] } ] }, { "uniprot_ac": "F1NCY7", "gene_name": "MAPKAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NCY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NCY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCY7" } ] } ] }, { "uniprot_ac": "F1NJH1", "gene_name": "PRKCH", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NJH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJH1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1NJH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJH1" } ] } ] }, { "uniprot_ac": "F1NKW3", "gene_name": "MAP3K15", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NKW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NKW3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1NKW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NKW3" } ] } ] }, { "uniprot_ac": "F1NLR7", "gene_name": "CLK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NLR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLR7" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "F1NLR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLR7" } ] } ] }, { "uniprot_ac": "F1NUX4", "gene_name": "MTOR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NUX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NUX4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NUX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NUX4" } ] } ] }, { "uniprot_ac": "F1NVF2", "gene_name": "MAP2K6", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NVF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVF2" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "F1NVF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVF2" } ] } ] }, { "uniprot_ac": "F1P011", "gene_name": "CAMK2A", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1P011", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P011" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F1P011", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P011" } ] } ] }, { "uniprot_ac": "F1P356", "gene_name": "NUAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1P356", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P356" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1P356", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P356" } ] } ] }, { "uniprot_ac": "F1P4G3", "gene_name": "HIPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1P4G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P4G3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1P4G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P4G3" } ] } ] }, { "uniprot_ac": "P05625", "gene_name": "RAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05625", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05625" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P05625", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05625" } ] } ] }, { "uniprot_ac": "P10741", "gene_name": "MOS", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P10741", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P10741" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P10741", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P10741" } ] } ] }, { "uniprot_ac": "P13863", "gene_name": "CDK1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13863" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13863" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13863" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13863" } ] } ] }, { "uniprot_ac": "P18652", "gene_name": "RPS6KA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P18652", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18652" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P18652", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18652" } ] } ] }, { "uniprot_ac": "P21868", "gene_name": "CSNK2A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P21868", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21868" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P21868", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21868" } ] } ] }, { "uniprot_ac": "P21869", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P21869", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21869" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P21869", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21869" } ] } ] }, { "uniprot_ac": "P53666", "gene_name": "LIMK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P53666", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P53666" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P53666", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P53666" } ] } ] }, { "uniprot_ac": "P67962", "gene_name": "CSNK1A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P67962", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67962" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P67962", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67962" } ] } ] }, { "uniprot_ac": "P79996", "gene_name": "MAPK9", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P79996", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P79996" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P79996", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P79996" } ] } ] }, { "uniprot_ac": "Q04982", "gene_name": "BRAF", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q04982", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q04982" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q04982", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q04982" } ] } ] }, { "uniprot_ac": "Q0GGW5", "gene_name": "STK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0GGW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0GGW5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0GGW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0GGW5" } ] } ] }, { "uniprot_ac": "Q5F3L1", "gene_name": "RPS6KA5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5F3L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3L1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5F3L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3L1" } ] } ] }, { "uniprot_ac": "Q5F3W3", "gene_name": "MAPK6", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5F3W3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3W3" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "Q5F3W3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3W3" } ] } ] }, { "uniprot_ac": "Q5ZIU3", "gene_name": "DYRK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5ZIU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZIU3" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q5ZIU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZIU3" } ] } ] }, { "uniprot_ac": "Q5ZJH6", "gene_name": "ULK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5ZJH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJH6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5ZJH6", "database": "UniProtKB", "url": 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"https://www.uniprot.org/uniprotkb/A0A1D5PCZ1#function" }, { "id": "A0A1D5PCZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PCZ1" } ], "binding_site_uniprot": 253, "amino_acid": "Asp", "chebi_lig_id": "CHEBI_29108", "ligand": "Ca(2+)", "ligand_label": "1", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 253, "end_pos": 253, "start_aa": "Asp", "end_aa": "Asp", "glycosite_overlap": "" } ], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.7.11.13", "ec_name": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "2.7.11.13", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13" }, { "id": "2.7.11.13", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.7.11.13" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 205, "end_pos": 207 }, { "start_pos": 223, "end_pos": 225 }, { "start_pos": 330, "end_pos": 332 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A1D5PNE8-1", "uniprot_ac": "A0A1D5PNE8", "uniprot_id": "A0A1D5PNE8_CHICK", "mass": { "chemical_mass": 140335.0, "monoisotopic_mass": 140335.0 }, "refseq": { "ac": "XP_418437", "name": "adenylate cyclase type 8 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418437" }, "gene_names": [ { "name": "ADCY8", "type": "recommended", "evidence": [ { "id": "A0A1D5PNE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNE8" } ] }, { "name": "ADCY8", "type": "synonym", "evidence": [ { "id": "XP_418437", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418437" } ] } ], "protein_names": [ { "name": "Adenylate cyclase type 8", "type": "recommended", "evidence": [ { "id": "A0A1D5PNE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNE8/entry#names_and_taxonomy" } ] }, { "name": "4.6.1.1", "type": "synonym", "evidence": [ { "id": "A0A1D5PNE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNE8/entry#names_and_taxonomy" } ] }, { "name": "adenylate cyclase type 8 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_418437", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418437" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052533.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Nov 16, 2006 this sequence version replaced XP_418437.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_418437", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418437" } ] }, { "annotation": "Catalyzes the formation of cAMP in response to calcium entry leadings to cAMP signaling activation that affect processes suche as synaptic plasticity and insulin secretion. Plays a role in many brain functions, such as learning, memory, drug addiction, and anxiety modulation through regulation of synaptic plasticity by modulating long-term memory and long-term potentiation (LTP) through CREB transcription factor activity modulation. Plays a central role in insulin secretion by controlling glucose homeostasis through glucagon-like peptide 1 and glucose signaling pathway and maintains insulin secretion through calcium-dependent PKA activation leading to vesicle pool replenishment. Also, allows PTGER3 to induce potentiation of PTGER4-mediated PLA2 secretion by switching from a negative to a positive regulation, during the IL1B induced-dedifferentiation of smooth muscle cells.", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PGV0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PGV0#function" }, { "database": "UniProtKB", "id": "ARBA00058052", "url": "https://www.uniprot.org/uniprotkb/ARBA00058052#function" }, { "database": "UniProtKB", "id": "A0A8V0XQQ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQQ8#function" }, { "database": "UniProtKB", "id": "A0A1D5PNE8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNE8#function" } ] }, { "annotation": "Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PGV0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PGV0#function" }, { "database": "UniProtKB", "id": "PIRNR039050", "url": "https://www.uniprot.org/uniprotkb/PIRNR039050#function" }, { "database": "UniProtKB", "id": "A0A8V0XQQ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQQ5#function" }, { "database": "UniProtKB", "id": "A0A8V0XQQ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQQ8#function" }, { "database": "UniProtKB", "id": "A0A1D5PNE8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNE8#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PNE8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNE8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ADCY8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNE8", "locus": { "chromosome": "2", "start_pos": 139868327, "end_pos": 139987072, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010007962", "url": "https://www.ensembl.org/id/ENSGALG00010007962" } ] } } ], "crossref": [ { "id": "A0A1D5PNE8", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PNE8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000030251", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000030251", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd07302", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07302", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "420328", "url": "https://www.ncbi.nlm.nih.gov/gene/420328", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001054", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001054", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009398", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009398", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018297", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018297", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029787", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029787", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030672", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030672", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032628", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032628", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:420328", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420328", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HRTIFIC", "url": "https://omabrowser.org/oma/group/HRTIFIC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PGV0", "url": "https://www.orthodb.org/?gene=A0A1D5PGV0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PNE8", "url": "https://www.orthodb.org/?gene=A0A1D5PNE8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XQQ5", "url": "https://www.orthodb.org/?gene=A0A8V0XQQ5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XQQ8", "url": "https://www.orthodb.org/?gene=A0A8V0XQQ8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45627", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45627", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45627:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45627:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00211", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00211", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF06327", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06327", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16214", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16214", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-163615", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-163615", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-170660", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-170660", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-170670", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-170670", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-418597", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-418597", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5610787", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5610787", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_418437", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418437", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "15389", "url": "https://www.rhea-db.org/rhea/15389", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A1D5PGV0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PGV0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PGV0-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PGV0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PNE8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNE8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PNE8-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNE8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XQQ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQQ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XQQ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQQ5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XQQ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQQ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XQQ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQQ8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MELSEVRCLSDSDELYTINRTPPGSSRPQRLLWQTAVRHITEQRFIQEHSSSSGGSSSVGGKGFSSEETCCPNHHPHHHHHHFRRQSAGRSLGSERHNNGGTKVFPERTSSNGDLGFLPLDCAPSNSDFFLNWGYTYRGVIFPTLRNSFKSRDLERLYQRYFLGQRRKSEVVMNILDVLTKLTLLFLHLTLASAPMDPIKGILLGFFTGIEVVICALVVVRKDTTSYTYLQYSGVVTWVAMATQILAAGLGCGLLGDGIGYVLFTLFATYSMLPLPLTWAILAGLVTSVLQLIMQLVIPRLAVTSLNQIAAQAVLFMCMNTAGIFISYLSDRAQRQAFLETRRCVEARLRLETENQRQERLVLSVLPRFVVLEMINDMTNVEDEHLQHQFHKIYIHRYENVSILFADVKGFTNLSTTLSAQELVRMLNELFARFDRLAHEHHCLRIKILGDCYYCVSGLPEPRQDHAHCCVEMGLSMIKTIRYVRSRTKHDIDMRIGIHSGSVLCGVLGLRKWQFDVWSWDVDIANKLESGGIPGRIHISKATLDCLNGDYKVEEGHGKERNEFLRKHNIETYLIKQPEESLLTLPEDIVKEAVSSSDSRNSGATFTEGSWSPELPFDNIVGKQNTLAALTRNSINLLPNHLAQALHVQSGPEEINKRIEHTIDLRSGDKLRREHIKPFSLMFKDSSLEHKYSQMRDEVFKSNLVCAFIVLVFITAIQSLLPSSRVIPMVIQFSILIMLHSALVLITTAEDYKCLPLMLRKTCCWINETYLARNVIIFASILINFLGAIINILWCDFDKPVPLKNQTFNSSASFSDICSYPEYFVFTGVLAMVTCAVFLRLNSVLKLAVLLIMIAIYALLTETIYASLFLQYDHLNHNGETDFLGTKEASLLLMAMFLLAVFYHGQQLEYTARLDFLWRVQAKEEINEMKELREHNENMLRNILPSHVARHFLEKDRDNEELYSQSYDAVGVMFASIPGFADFYSQTEMNNQGVECLRLLNEIIADFDELLGEERFQDIEKIKTIGSTYMAVSGLSPEKQQCEDKWGHLCALADFSIALNESIQEINKHSFNNFELRIGISHGSVVAGVIGAKKPQYDIWGKTVNLASRMDSTGVSDRIQVPEETYLILKDRGFAFDYRGEIYVKGISEQEGKIKTYFLLGRVQPNPLILQPRKLTGQYSLAAVVLGLVQSLNRQKQKQILNENNNSGIIKGHYNRRTLLTPGGSEAAAQAEGADKTELP", "length": 1240, "header": "tr|A0A1D5PNE8-1|A0A1D5PNE8_CHICK Isoform 1 of Adenylate cyclase type 8 OS=Gallus gallus OX=9031 GN=ADCY8 PE=3 SV=1 CANONICAL=A0A1D5PNE8-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PGV0-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNE8/entry#A0A1D5PGV0-1", "sequence": { "sequence": "MELSEVRCLSDSDELYTINRTPPGSSRPQRLLWQTAVRHITEQRFIQEHSSSSGGSSSVGGKGFSSEETCCPNHHPHHHHHHFRRQSAGRSLGSERHNNGGTKVFPERTSSNGDLGFLPLDCAPSNSDFFLNWGYTYRGVIFPTLRNSFKSRDLERLYQRYFLGQRRKSEVVMNILDVLTKLTLLFLHLTLASAPMDPIKGILLGFFTGIEVVICALVVVRKDTTSYTYLQYSGVVTWVAMATQILAAGLGCGLLGDGIGYVLFTLFATYSMLPLPLTWAILAGLVTSVLQLIMQLVIPRLAVTSLNQIAAQAVLFMCMNTAGIFISYLSDRAQRQAFLETRRCVEARLRLETENQRQERLVLSVLPRFVVLEMINDMTNVEDEHLQHQFHKIYIHRYENVSILFADVKGFTNLSTTLSAQELVRMLNELFARFDRLAHEHHCLRIKILGDCYYCVSGLPEPRQDHAHCCVEMGLSMIKTIRYVRSRTKHDIDMRIGIHSGSVLCGVLGLRKWQFDVWSWDVDIANKLESGGIPGRIHISKATLDCLNGDYKVEEGHGKERNEFLRKHNIETYLIKQPEESLLTLPEDIVKEAVSSSDSRNSGATFTEGSWSPELPFDNIVGKQNYSQMRDEVFKSNLVCAFIVLVFITAIQSLLPSSRVIPMVIQFSILIMLHSALVLITTAEDYKCLPLMLRKTCCWINETYLARNVIIFASILINFLGAIINILWCDFDKPVPLKNQTFNSSASFSDICSYPEYFVFTGVLAMVTCAVFLRLNSVLKLAVLLIMIAIYALLTETIYASLFLQYDHLNHNGETDFLGTKEASLLLMAMFLLAVFYHGQQLEYTARLDFLWRVQAKEEINEMKELREHNENMLRNILPSHVARHFLEKDRDNEELYSQSYDAVGVMFASIPGFADFYSQTEMNNQGVECLRLLNEIIADFDELLGEERFQDIEKIKTIGSTYMAVSGLSPEKQQCEDKWGHLCALADFSIALNESIQEINKHSFNNFELRIGISHGSVVAGVIGAKKPQYDIWGKTVNLASRMDSTGVSDRIQVPEETYLILKDRGFAFDYRGEIYVKGISEQEGKIKTYFLLGRVQPNPLILQPRKLTGQYSLAAVVLGLVQSLNRQKQKQILNENNNSGIIKGHYNRRTLLTPGGSEAAAQAEGADKTELP", "length": 1174, "header": "tr|A0A1D5PGV0-1|A0A1D5PNE8_CHICK Computationally mapped isoform of Adenylate cyclase type 8 OS=Gallus gallus OX=9031 GN=ADCY8 PE=3 SV=1 CANONICAL=A0A1D5PNE8-1" }, "locus": { "chromosome": "2", "start_pos": 139986243, "end_pos": 139868408, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010018986.1", "url": "https://www.ensembl.org/id/ENSGALT00010018986.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010010535.1", "url": "https://www.ensembl.org/id/ENSGALP00010010535.1" } ] } }, { "isoform_ac": "A0A1D5PNE8-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNE8/entry#A0A1D5PNE8-1", "sequence": { "sequence": "MELSEVRCLSDSDELYTINRTPPGSSRPQRLLWQTAVRHITEQRFIQEHSSSSGGSSSVGGKGFSSEETCCPNHHPHHHHHHFRRQSAGRSLGSERHNNGGTKVFPERTSSNGDLGFLPLDCAPSNSDFFLNWGYTYRGVIFPTLRNSFKSRDLERLYQRYFLGQRRKSEVVMNILDVLTKLTLLFLHLTLASAPMDPIKGILLGFFTGIEVVICALVVVRKDTTSYTYLQYSGVVTWVAMATQILAAGLGCGLLGDGIGYVLFTLFATYSMLPLPLTWAILAGLVTSVLQLIMQLVIPRLAVTSLNQIAAQAVLFMCMNTAGIFISYLSDRAQRQAFLETRRCVEARLRLETENQRQERLVLSVLPRFVVLEMINDMTNVEDEHLQHQFHKIYIHRYENVSILFADVKGFTNLSTTLSAQELVRMLNELFARFDRLAHEHHCLRIKILGDCYYCVSGLPEPRQDHAHCCVEMGLSMIKTIRYVRSRTKHDIDMRIGIHSGSVLCGVLGLRKWQFDVWSWDVDIANKLESGGIPGRIHISKATLDCLNGDYKVEEGHGKERNEFLRKHNIETYLIKQPEESLLTLPEDIVKEAVSSSDSRNSGATFTEGSWSPELPFDNIVGKQNTLAALTRNSINLLPNHLAQALHVQSGPEEINKRIEHTIDLRSGDKLRREHIKPFSLMFKDSSLEHKYSQMRDEVFKSNLVCAFIVLVFITAIQSLLPSSRVIPMVIQFSILIMLHSALVLITTAEDYKCLPLMLRKTCCWINETYLARNVIIFASILINFLGAIINILWCDFDKPVPLKNQTFNSSASFSDICSYPEYFVFTGVLAMVTCAVFLRLNSVLKLAVLLIMIAIYALLTETIYASLFLQYDHLNHNGETDFLGTKEASLLLMAMFLLAVFYHGQQLEYTARLDFLWRVQAKEEINEMKELREHNENMLRNILPSHVARHFLEKDRDNEELYSQSYDAVGVMFASIPGFADFYSQTEMNNQGVECLRLLNEIIADFDELLGEERFQDIEKIKTIGSTYMAVSGLSPEKQQCEDKWGHLCALADFSIALNESIQEINKHSFNNFELRIGISHGSVVAGVIGAKKPQYDIWGKTVNLASRMDSTGVSDRIQVPEETYLILKDRGFAFDYRGEIYVKGISEQEGKIKTYFLLGRVQPNPLILQPRKLTGQYSLAAVVLGLVQSLNRQKQKQILNENNNSGIIKGHYNRRTLLTPGGSEAAAQAEGADKTELP", "length": 1240, "header": "tr|A0A1D5PNE8-1|A0A1D5PNE8_CHICK Isoform 1 of Adenylate cyclase type 8 OS=Gallus gallus OX=9031 GN=ADCY8 PE=3 SV=1 CANONICAL=A0A1D5PNE8-1" }, "locus": { "chromosome": "2", "start_pos": 139986243, "end_pos": 139868408, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010018980.1", "url": "https://www.ensembl.org/id/ENSGALT00010018980.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010010529.1", "url": "https://www.ensembl.org/id/ENSGALP00010010529.1" } ] } }, { "isoform_ac": "A0A8V0XQQ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNE8/entry#A0A8V0XQQ5-1", "sequence": { "sequence": "MELSEVRCLSDSDELYTINRTPPGSSRPQRLLWQTAVRHITEQRFIQEHSSSSGGSSSVGGKGFSSEETCCPNHHPHHHHHHFRRQSAGRSLGSERHNNGGTKVFPERTSSNGDLGFLPLDCAPSNSDFFLNWGYTYRGVIFPTLRNSFKSRDLERLYQRYFLGQRRKSEVVMNILDVLTKLTLLFLHLTLASAPMDPIKGILLGFFTGIEVVICALVVVRKDTTSYTYLQYSGVVTWVAMATQILAAGLGCGLLGDGIGYVLFTLFATYSMLPLPLTWAILAGLVTSVLQLIMQLVIPRLAVTSLNQIAAQAVLFMCMNTAGIFISYLSDRAQRQAFLETRRCVEARLRLETENQRQERLVLSVLPRFVVLEMINDMTNVEDEHLQHQFHKIYIHRYENVSILFADVKGFTNLSTTLSAQELVRMLNELFARFDRLAHEHHCLRIKILGDCYYCVSGLPEPRQDHAHCCVEMGLSMIKTIRRIHISKATLDCLNGDYKVEEGHGKERNEFLRKHNIETYLIKQPEESLLTLPEDIVKEAVSSSDSRNSGATFTEGSWSPELPFDNIVGKQNTLAALTRNSINLLPNHLAQALHVQSGPEEINKRIEHTIDLRSGDKLRREHIKPFSLMFKDSSLEHKYSQMRDEVFKSNLVCAFIVLVFITAIQSLLPSSRVIPMVIQFSILIMLHSALVLITTAEDYKCLPLMLRKTCCWINETYLARNVIIFASILINFLGAIINILWCDFDKPVPLKNQTFNSSASFSDICSYPEYFVFTGVLAMVTCAVFLRLNSVLKLAVLLIMIAIYALLTETIYASLFLQYDHLNHNGETDFLGTKEASLLLMAMFLLAVFYHGQQLEYTARLDFLWRVQAKEEINEMKELREHNENMLRNILPSHVARHFLEKDRDNEELYSQSYDAVGVMFASIPGFADFYSQTEMNNQGVECLRLLNEIIADFDELLGEERFQDIEKIKTIGSTYMAVSGLSPEKQQCEDKWGHLCALADFSIALNESIQEINKHSFNNFELRIGISHGSVVAGVIGAKKPQYDIWGKTVNLASRMDSTGVSDRIQVPEETYLILKDRGFAFDYRGEIYVKGISEQEGKIKTYFLLGRVQPNPLILQPRKLTGQYSLAAVVLGLVQSLNRQKQKQILNENNNSGIIKGHYNRRTLLTPGGSEAAAQAEGADKTELP", "length": 1187, "header": "tr|A0A8V0XQQ5-1|A0A1D5PNE8_CHICK Computationally mapped isoform of Adenylate cyclase type 8 OS=Gallus gallus OX=9031 GN=ADCY8 PE=3 SV=1 CANONICAL=A0A1D5PNE8-1" }, "locus": { "chromosome": "2", "start_pos": 139986243, "end_pos": 139868408, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010018982.1", "url": "https://www.ensembl.org/id/ENSGALT00010018982.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010010531.1", "url": "https://www.ensembl.org/id/ENSGALP00010010531.1" } ] } }, { "isoform_ac": "A0A8V0XQQ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNE8/entry#A0A8V0XQQ8-1", "sequence": { "sequence": "MELSEVRCLSDSDELYTINRTPPGSSRPQRLLWQTAVRHITEQRFIQEHSSSSGGSSSVGGKGFSSEETCCPNHHPHHHHHHFRRQSAGRSLGSERHNNGGTKVFPERTSSNGDLGFLPLDCAPSNSDFFLNWGYTYRGVIFPTLRNSFKSRDLERLYQRYFLGQRRKSEVVMNILDVLTKLTLLFLHLTLASAPMDPIKGILLGFFTGIEVVICALVVVRKDTTSYTYLQYSGVVTWVAMATQILAAGLGCGLLGDGIGYVLFTLFATYSMLPLPLTWAILAGLVTSVLQLIMQLVIPRLAVTSLNQIAAQAVLFMCMNTAGIFISYLSDRAQRQAFLETRRCVEARLRLETENQRQERLVLSVLPRFVVLEMINDMTNVEDEHLQHQFHKIYIHRYENVSILFADVKGFTNLSTTLSAQELVRMLNELFARFDRLAHEHHCLRIKILGDCYYCVSGLPEPRQDHAHCCVEMGLSMIKTIRYVRSRTKHDIDMRIGIHSGSVLCGVLGLRKWQFDVWSWDVDIANKLESGGIPGRIHISKATLDCLNGDYKVEEGHGKERNEFLRKHNIETYLIKQPEESLLTLPEDIVKEAVSSSDSRNSGATFTEGSWSPELPFDNIVGKQNLWCDFDKPVPLKNQTFNSSASFSDICSYPEYFVFTGVLAMVTCAVFLRLNSVLKLAVLLIMIAIYALLTETIYASLFLQYDHLNHNGETDFLGTKEASLLLMAMFLLAVFYHGQQLEYTARLDFLWRVQAKEEINEMKELREHNENMLRNILPSHVARHFLEKDRDNEELYSQSYDAVGVMFASIPGFADFYSQTEMNNQGVECLRLLNEIIADFDELLGEERFQDIEKIKTIGSTYMAVSGLSPEKQQCEDKWGHLCALADFSIALNESIQEINKHSFNNFELRIGISHGSVVAGVIGAKKPQYDIWGKTVNLASRMDSTGVSDRIQVPEETYLILKDRGFAFDYRGEIYVKGISEQEGKIKTYFLLGRVQPNPLILQPRKLTGQYSLAAVVLGLVQSLNRQKQKQILNENNNSGIIKGHYNRRTLLTPGGSEAAAQAEGADKTELP", "length": 1073, "header": "tr|A0A8V0XQQ8-1|A0A1D5PNE8_CHICK Computationally mapped isoform of Adenylate cyclase type 8 OS=Gallus gallus OX=9031 GN=ADCY8 PE=3 SV=1 CANONICAL=A0A1D5PNE8-1" }, "locus": { "chromosome": "2", "start_pos": 139986243, "end_pos": 139868408, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010018987.1", "url": "https://www.ensembl.org/id/ENSGALT00010018987.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010010536.1", "url": "https://www.ensembl.org/id/ENSGALP00010010536.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:420328", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420328", "resource": "KEGG Pathway" }, { "id": "R-GGA-163615", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-163615", "resource": "Reactome", "description": "PKA activation" }, { "id": "R-GGA-170660", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-170660", "resource": "Reactome", "description": "Adenylate cyclase activating pathway" }, { "id": "R-GGA-170670", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-170670", "resource": "Reactome", "description": "Adenylate cyclase inhibitory pathway" }, { "id": "R-GGA-418597", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-418597", "resource": "Reactome", "description": "G alpha (z) signalling events" }, { "id": "R-GGA-5610787", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5610787", "resource": "Reactome", "description": "Hedgehog 'off' state" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287AWF4-1", "protein_name": "Adenylate cyclase type 8", "gene_name": "ADCY8", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MELSDVRCLSGSEELYTIHPTPPAGDGGSGSRPQRLLWQTAVRHITEQRFIHGHRGSGGSGSGGSGKASDPAGGGPNHHASQLSGGDSALPLYSLGPRERAHSTGGTKVFPERSGSGSGSGGGGDLGFLHLDCAPSNSDFFLSGGYSYRGVIFPTLRNSFKSRDLERLYQRYFLGQRRKSEVVMNVLDVLTKLTLLVLHLSLASAPMDPLKGILLGFFTGIEVVICALVVVRKDTTSHTYLQYSGLVTWVAMTTQILAAGLGYGLLGDGIGYVLFTLFATYSMLPLPLTWAILAGLGTSLLQVVLQVLIPRLAVISINQVAAQAVLFMCMNTAGIFISYLSDRAQRQAFLETRRCVEARLRLETENQRQERLVLSVLPRFVVLEMINDMTNVEDEHLQHQFHRIYIHRYENVSILFADVKGFTNLSTTLSAQELVRMLNELFARFDRLAHEHHCLRIKILGDCYYCVSGLPEPRQDHAHCCVEMGLSMIKTIRYVRSRTKHDVDMRIGIHSGSVLCGVLGLRKWQFDVWSWDVDIANKLESGGIPGRIHISKATLDCLNGDYSVEEGHGKERNEFLRKHNIETYLIKQPEESLLSLPEDIVKESVSSSDRRNSGATFTEGSWSPELPFDNIVGKQNTLAALTRNSINLLPNHLAQALHVQSGPEEINKRIEHTIDLRSGDKLRREHIKPFSLMFKDSSLEHKYSQMRDEVFKSNLVCAFIVLLFITAIQSLLPSSRVMPMVIQFSILIMLHSALVLITTAEDYKCLPLVLRKTCCWINETYLARNVIIFASILINFLGAILNILWCDFDKSIPLKNLTFNSSAVFTDICSYPEYFVFTGVLAMVTCAVFLRLNSVLKLAVLLIMIAIYALLTETIYAGLFLRYDNLNHSGEDFLGTKEASLLLMAMFLLAVFYHGQQLEYTARLDFLWRVQAKEEINEMQELREHNENMLRNILPSHVARHFLEKDRDNEELYSQSYDAVGVMFASIPGFADFYSQTEMNNQGVECLRLLNEIIADFDELLGEDRFQDIEKIKTIGSTYMAVSGLSPEKQQCEDKWEHLCALADFSLALTESIQEINKHSFNNFELRIGISHGSVVAGVIGAKKPQYDIWGKTVNLASRMDSTGVSGRIQVPEETYLILKDQGFAFDYRGEIYVKGISEQEGKIKTYFLLGRVQPNPFILPPRRLPGQYSLAAVVLGLVQSLNRQRQKQLLNENSNPGIIKGHYNRRTLLTPSGPEPGAQAEGPDKSELP", "length": 1250 }, "evidence": [ { "id": "A0A1D5PNE8", "url": "https://omabrowser.org/oma/group/A0A1D5PNE8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "E1BQ12-1", "protein_name": "Adenylate cyclase type 8", "gene_name": "ADCY8", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MELSDVRCLSGSEELYTIHPTPPAGDSGSGSRPQRLLWQTAVRHITEQRFIHGHRGGGGGGGNGSSSKASDPGGGGPNHHHASQLSGDSALPLYALGPGERAHGTGGPKVFPERSGSGSASGSGGGGDLGFLHLDCAPSNSDFFLNGGYSYRGVIFPTLRNSFKSRDLERLYQRYFLGQRRKSEVVMNVLDVLTKLTLLVLHLSLASAPMDPLKGILLGFFTGIEVVICALVVVRKDTTSHTYLQYSGVVTWVAMTTQILAAGLGYGLLGDGIGYVLFTLFATYSMLPLPLTWAILAGLGTSLMQVVLQAVIPRLAVISINQVVAQAVLFMCMNTAGIFISYLSDRAQRQAFLETRRCVEARLRLETENQRQERLVLSVLPRFVVLEMINDMTNVEDEHLQHQFHRIYIHRYENVSILFADVKGFTNLSTTLSAQELVRMLNELFARFDRLAHEHHCLRIKILGDCYYCVSGLPEPRQDHAHCCVEMGLSMIKTIRYVRSRTKHDVDMRIGIHSGSVLCGVLGLRKWQFDVWSWDVDIANKLESGGIPGRIHISKATLDCLNGDYNVEEGHGKERNEFLRKHNIETYLIKQPEESLLSLPEDIVKESVSSSDRRNSGATFTEGSWSPELPFDNIVGKQNTLAALTRNSINLLPNHLAQALHVQSGPEEINKRIEHTIDLRSGDKLRREHIKPFSLMFKDSSLEHKYSQMRDEVFKSNLVCAFIVLLFITAIQSLLPSSRVMPMAIQFSILIMLHSALVLITTAEDYKCLPLVLRKTCCWINETYLARNVIIFASILINFLGAILNILWCDFDKSIPLKNLTFNSSAVFTDICSYPEYFVFTGVLAMVTCAVFLRLNSVLKLAVLLIMIAIYALLTETIYAGLFLRYDNLNHSGEDFLGTKEASLLLMAMFLLAVFYHGQQLEYTARLDFLWRVQAKEEINEMKELREHNENMLRNILPSHVARHFLEKDRDNEELYSQSYDAVGVMFASIPGFADFYSQTEMNNQGVECLRLLNEIIADFDELLGEDRFQDIEKIKTIGSTYMAVSGLSPEKQQCEDKWGHLCALADFSLALTESIQEINKHSFNNFELRIGISHGSVVAGVIGAKKPQYDIWGKTVNLASRMDSTGVSGRIQVPEETYLILKDQGFAFDYRGEIYVKGISEQEGKIKTYFLLGRVQPNPFILPPRRLPGQYSLAAVVLGLVQSLNRQRQKQLLNENNNTGIIKGHYNRRTLLTPSGPEPGAPAEGADKPELP", "length": 1253 }, "evidence": [ { "id": "A0A1D5PNE8", "url": "https://omabrowser.org/oma/group/A0A1D5PNE8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P40145-1", "protein_name": "Adenylate cyclase type 8", "gene_name": "ADCY8", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MELSDVRCLTGSEELYTIHPTPPAGDGRSASRPQRLLWQTAVRHITEQRFIHGHRGGSGSGSGGSGKASDPAGGGPNHHAPQLSGDSALPLYSLGPGERAHSTCGTKVFPERSGSGSASGSGGGGDLGFLHLDCAPSNSDFFLNGGYSYRGVIFPTLRNSFKSRDLERLYQRYFLGQRRKSEVVMNVLDVLTKLTLLVLHLSLASAPMDPLKGILLGFFTGIEVVICALVVVRKDTTSHTYLQYSGVVTWVAMTTQILAAGLGYGLLGDGIGYVLFTLFATYSMLPLPLTWAILAGLGTSLLQVILQVVIPRLAVISINQVVAQAVLFMCMNTAGIFISYLSDRAQRQAFLETRRCVEARLRLETENQRQERLVLSVLPRFVVLEMINDMTNVEDEHLQHQFHRIYIHRYENVSILFADVKGFTNLSTTLSAQELVRMLNELFARFDRLAHEHHCLRIKILGDCYYCVSGLPEPRQDHAHCCVEMGLSMIKTIRYVRSRTKHDVDMRIGIHSGSVLCGVLGLRKWQFDVWSWDVDIANKLESGGIPGRIHISKATLDCLNGDYNVEEGHGKERNEFLRKHNIETYLIKQPEDSLLSLPEDIVKESVSSSDRRNSGATFTEGSWSPELPFDNIVGKQNTLAALTRNSINLLPNHLAQALHVQSGPEEINKRIEHTIDLRSGDKLRREHIKPFSLMFKDSSLEHKYSQMRDEVFKSNLVCAFIVLLFITAIQSLLPSSRVMPMTIQFSILIMLHSALVLITTAEDYKCLPLILRKTCCWINETYLARNVIIFASILINFLGAILNILWCDFDKSIPLKNLTFNSSAVFTDICSYPEYFVFTGVLAMVTCAVFLRLNSVLKLAVLLIMIAIYALLTETVYAGLFLRYDNLNHSGEDFLGTKEVSLLLMAMFLLAVFYHGQQLEYTARLDFLWRVQAKEEINEMKELREHNENMLRNILPSHVARHFLEKDRDNEELYSQSYDAVGVMFASIPGFADFYSQTEMNNQGVECLRLLNEIIADFDELLGEDRFQDIEKIKTIGSTYMAVSGLSPEKQQCEDKWGHLCALADFSLALTESIQEINKHSFNNFELRIGISHGSVVAGVIGAKKPQYDIWGKTVNLASRMDSTGVSGRIQVPEETYLILKDQGFAFDYRGEIYVKGISEQEGKIKTYFLLGRVQPNPFILPPRRLPGQYSLAAVVLGLVQSLNRQRQKQLLNENNNTGIIKGHYNRRTLLSPSGTEPGAQAEGTDKSDLP", "length": 1251 }, "evidence": [ { "id": "A0A1D5PNE8", "url": "https://omabrowser.org/oma/group/A0A1D5PNE8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P40146-1", "protein_name": "Adenylate cyclase type 8", "gene_name": "Adcy8", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MELSDVHCLSGSEELYTIHPTPPAADGGSGSRPQRLLWQTAVRHITEQRFIHGHRGGGGGGSRKASNPAGSGPNHHAPQLSSDSVLPLYSLGSGERAHNTGGTKVFPERSGSGSASGSGGGGDLGFLHLDCAPSNSDFFLNGGYSYRGVIFPTLRNSFKSRDLERLYQRYFLGQRRKSEVVMNVLDVLTKLTLLVLHLSLASAPMDPLKGILLGFFTGIEVVICALVVVRKDTTSHTYLQYSGVVTWVAMTTQILAAGLGYGLLGDGIGYVLFTLFATYSMLPLPLTWAILAGLGTSLLQVTLQVLIPRLAVFSINQVLAQVVLFMCMNTAGIFISYLSDRAQRQAFLETRRCVEARLRLETENQRQERLVLSVLPRFVVLEMINDMTNVEDEHLQHQFHRIYIHRYENVSILFADVKGFTNLSTTLSAQELVRMLNELFARFDRLAHEHHCLRIKILGDCYYCVSGLPEPRQDHAHCCVEMGLSMIKTIRFVRSRTKHDVDMRIGIHSGSVLCGVLGLRKWQFDVWSWDVDIANKLESGGIPGRIHISKATLDCLSGDYNVEEGHGKERNEFLRKHNIETYLIKQPEESLLSLPEDIVKESVSCSDRRNSGATFTEGSWSPELPFDNIVGKQNTLAALTRNSINLLPNHLAQALHVQSGPEEINKRIEHTIDLRSGDKLRREHIKPFSLMFKDSSLEHKYSQMRDEVFKSNLVCAFIVLLFITAIQSLLPSSRLMPMTIQFSILIMLHSALVLITTAEDYKCLPLILRKTCCWINETYLARNVIIFASILINFLGAVINILWCDFDKSIPLKNLTFNSSAVFTDICSYPEYFVFTGVLAMVTCAVFLRLNSVLKLAVLLIMIAIYALLTETIYAGLFLSYDNLNHSGEDFLGTKEASLLLMAMFLLAVFYHGQQLEYTARLDFLWRVQAKEEINEMKDLREHNENMLRNILPGHVARHFLEKDRDNEELYSQSYDAVGVMFASIPGFADFYSQTEMNNQGVECLRLLNEIIADFDELLGEDRFQDIEKIKTIGSTYMAVSGLSPEKQQCEDKWGHLCALADFSLALTESIQEINKHSFNNFELRIGISHGSVVAGVIGAKKPQYDIWGKTVNLASRMDSTGVSGRIQVPEETYLILKDQGFAFDYRGEIYVKGISEQEGKIKTYFLLGRVQPNPFILPPRRLPGQYSLAAVVLGLVQSLNRQRQKQLLNENSNSGIIKSHYNRRTLLTPSGPEPGAQAEGTDKSDLP", "length": 1248 }, "evidence": [ { "id": "A0A1D5PNE8", "url": "https://omabrowser.org/oma/group/A0A1D5PNE8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P97490-1", "protein_name": "Adenylate cyclase type 8", "gene_name": "Adcy8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MELSDVHCLSGSEELYTIQPTPPAGDDGSGSRPQRLLWQTAVRHITEQRFIHGHRGGGGGGVSRKASNPAGSGPNHHAPQLSSDSVLPLYSLGPGERAHNTGGTKVFPERSGSGSASGSGGGGDLGFLHLDCAPSNSDFFLNGGYSYRGVIFPTLRNSFKSRDLERLYQRYFLGQRRKSEVVMNVLDVLTKLTLLVLHLSLASAPMDPLKGILLGFFTGIEVVICALVVVRKDNTSHTYLQYSGVVTWVAMTTQILAAGLGYGLLGDGIGYVLFTLFATYSMLPLPLTWAILAGLGTSLLQVTLQVLIPRLAVFSINQVLAQVVLFMCMNTAGIFISYLSDRAQRQAFLETRRCVEARLRLETENQRQERLVLSVLPRFVVLEMINDMTNVEDEHLQHQFHRIYIHRYENVSILFADVKGFTNLSTTLSAQELVRMLNELFARFDRLAHEHHCLRIKILGDCYYCVSGLPEPRRDHAHCCVEMGLSMIKTIRFVRSRTKHDVDMRIGIHSGSVLCGVLGLRKWQFDVWSWDVDIANKLESGGIPGRIHISKATLDCLNGDYNVEEGHGKERNEFLRKHNIETYLIKQPEESLLCLPEDIVKESVSCSDRRNSGATFTEGSWSPELPFDNIVGKQNTLAALTRNSINLLPNHLAQALHVQSGPEEINKRIEHTIDLRSGDKLRREHIKPFSLMFKDSSLEHKYSQMRDEVFKSNLVCAFIVLLFITAIQSLLPSSRLMPMTIQFSILIMLHSALVLITTAEDYKCLPLILRKTCCWINETYLARNVIIFASILINFLGAVLNILWCDFDKSIPLKNLTFNSSAVFTDICSYPEYFVFTGVLAMVTCAVFLRLNSVLKLAVLLIMIAIYALLTETIYAGLFLSYDNLNHSGEDFLGTKEASLLLMAMFLLAVFYHGQQLEYTARLDFLWRVQAKEEINEMKELREHNENMLRNILPSHVARHFLEKDRDNEELYSQSYDAVGVMFASIPGFADFYSQTEMNNQGVECLRLLNEIIADFDELLGEDRFQDIEKIKTIGSTYMAVSGLSPEKQQCEDKWGHLCALADFSLALTESIQEINKHSFNNFELRIGISHGSVVAGVIGAKKPQYDIWGKTVNLASRMDSTGVSGRIQVPEETYLILKDQGFAFDYRGEIYVKGISEQEGKIKTYFLLGRVQPNPFILPPRRLPGQYSLAAVVLGLVQSLNRQRQKQLLNENSNSGIIKSHYNRRTLLTPSGPEPGAQAEGTDKSDLP", "length": 1249 }, "evidence": [ { "id": "A0A1D5PNE8", "url": "https://omabrowser.org/oma/group/A0A1D5PNE8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VP76-1", "protein_name": "Adenylyl cyclase 78C", "gene_name": "Ac78C", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDVELEEEEERICLRTAEEGQLANMDDDKLVSDEVHLRQLSATPSSAFSLQHSRGSDTKEEAPPEGGTMGGKSAAPREEGEPDERVVLRRAVDKGAIALAQIDDLKLEGDDDDEAVVNGEEVDGLGLSNPAAQTTDDEQITVNGTGAAATSSVAADAASSEQDAASTAMATPDMSKIPRLPGDGAQMEDNGSGDLPPSLRASTTSILSNLRKKQQGGPLRGGVAKQTPLRVQSVRIVEAKRAYGPKRRTESCSIFGNSNFEHDLESGNSLASIPGQSQRPLNNEMYSAFKSGNVVKGILCPSLTNSFKQSSLERSYLTYTHRQRQKSLIIVNVVDFVLKIVLAFVWIMRRSELGPIESDDGTSMATAITWSVCCGIANMAICFLGYWRCFANNYLHWAAVCTWVLFNIQGFVGQGVGFADREYLVWYILFVIFVPYAMLPLPLKWCVVGGTITASCHLAVITIIKLQHGEATINPECVLFQIFANFILYTAINVAGMYTKYLTDRGQRLAFIETHKAMEHKKESEKELQRTQKLLDSILPNIVNNQIRSEMYKGTDPTVETQFNKLYVYPMDNVSILFADIKGFTELASKTSAQQLVKILNDLFARFDRIAEDNHCLRVKLLGDCYYCVSQFESDNWKTRPDHAVCSVETGLHMIKAIKDVRLHTHVDLNMRIGIHSGSVMCGVLGNKKWHFDVWSNDVIIANHMESGGIPGRVHISEATLKCLNDAYEVEPGNGGCRDNHLKMLNVKTYLIKRTEPLRPKRRFGTRSSAHLAGSVATAAPPCATPTALPKSISASGSGSIGGVTATGNDGASIDGRSLEYAATIAVPAQQPTQLLQQQQKKNISLNSLPNVVEGVAMDSRRIRNGCGVMGGAGGTGGGGTGPCGMSTVSSPTAMMSAPLEVQLRPRNGACSIQNLAEAIDGKGLIIEDESTTDWIPEIPFKNLNSPEDGLNRADSILVDTKEDHRVSVAVLDEEIDEFIEQNIQINSNKEIRREYLNPWTLKFKDKSQEQKFCQLREDMFRSNMLCVFVIWIFMVLCQVIIIPRCTRLIICLSVGTVILTFCCVLVMAEEFPGLPRCLKTNSAKLVHQRQRRTLFICGVIVSMCMLSAIGLVLCPSSTYIGTADEHSRFLRMVSPYSNISMTEKEFKLNVYLSATIHHNITISTPASGGPTPLVDITSSGPSDEFVRSTLNALTLNLTPPLPQSHRPYTLTTNGHSVSLSNLSYSDASVMQSSSDVEGQCAHPEYLVFTWVLCLVSLATALKLYYLVKALMALAMVAFYTTLIMMKFGSGDSFSLVELSRLGMPLGVQMLILLISFLVMVCYHARLVEVTSRLDFIWKEQAERELTNMKSNRALNDTLIKNILPDHVATYYLSDEHTDELYSKMHNLCGVMFASIPNFQDFYSEDIDNGKACIRILNEIICDFDELLEEPRFASVEKIKTVGATYMAAAGLNHEHLRLRGETSEDSVCDLVEFAFAMKQKLEEINGDAFNNFQLRVGICSGPLVSGVIGARKPVYDIWGNTVNVASRMDSTGENWRVQVPENTAELLCSRGYTCVKRGEIAVKGKGMMTTFYVHPKGISESQLISPVRMPAGIPLAQTPNLQRQTSHHGSFSAVVFGMLQASKRSTAIAGTPTGTPSPQIRRGHRGSTFSSVRLSQKSTTVNPVRRNTTRVRGRSYRQKKSSSNNSIVTQASSSYMPSFRRIDQIETTISKSHNDAL", "length": 1718 }, "evidence": [ { "id": "A0A1D5PNE8", "url": "https://omabrowser.org/oma/group/A0A1D5PNE8/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "adenylate cyclase activity", "id": "GO:0004016", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004016", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PNE8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNE8" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PNE8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNE8" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PNE8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNE8" } ], "pmid": "" }, { "name": "calcium- and calmodulin-responsive adenylate cyclase activity", "id": "GO:0008294", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008294", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PNE8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNE8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 15, "go_terms": [ { "name": "clathrin-coated pit", "id": "GO:0005905", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005905", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PNE8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNE8" } ], "pmid": "" }, { "name": "postsynaptic density", "id": "GO:0014069", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014069", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PNE8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNE8" } ], "pmid": "" }, { "name": "basolateral plasma membrane", "id": "GO:0016323", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016323", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PNE8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNE8" } ], "pmid": "" }, { "name": "dendrite", "id": "GO:0030425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PNE8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNE8" } ], "pmid": "" }, { "name": "apical plasma membrane", "id": "GO:0016324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016324", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PNE8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNE8" } ], "pmid": "" }, { "name": "clathrin-coated vesicle membrane", "id": "GO:0030665", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030665", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PNE8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNE8" } ], "pmid": "" }, { "name": "caveola", "id": "GO:0005901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005901", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PNE8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNE8" } ], "pmid": "" }, { "name": "presynaptic membrane", "id": "GO:0042734", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042734", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PNE8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNE8" } ], "pmid": "" }, { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PNE8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNE8" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PNE8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNE8" } ], "pmid": "" }, { "name": "axon", "id": "GO:0030424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030424", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PNE8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNE8" } ], "pmid": "" }, { "name": "presynaptic active zone", "id": "GO:0048786", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048786", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PNE8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNE8" } ], "pmid": "" }, { "name": "neuronal cell body membrane", "id": "GO:0032809", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032809", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PNE8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNE8" } ], "pmid": "" }, { "name": "excitatory synapse", "id": "GO:0060076", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060076", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PNE8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNE8" } ], "pmid": "" }, { "name": "Schaffer collateral - CA1 synapse", "id": "GO:0098685", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098685", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PNE8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNE8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 16, "go_terms": [ { "name": "cAMP biosynthetic process", "id": "GO:0006171", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006171", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PNE8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNE8" } ], "pmid": "" }, { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PNE8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNE8" } ], "pmid": "" }, { "name": "regulation of insulin secretion", "id": "GO:0050796", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050796", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PNE8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNE8" } ], "pmid": "" }, { "name": "adenylate cyclase-activating G protein-coupled receptor signaling pathway", "id": "GO:0007189", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007189", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PNE8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNE8" } ], "pmid": "" }, { "name": "memory", "id": "GO:0007613", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007613", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PNE8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNE8" } ], "pmid": "" }, { "name": "locomotory behavior", "id": "GO:0007626", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007626", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PNE8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNE8" } ], "pmid": "" }, { "name": "cellular response to glucagon stimulus", "id": "GO:0071377", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071377", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PNE8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNE8" } ], "pmid": "" }, { "name": "positive regulation of long-term synaptic potentiation", "id": "GO:1900273", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900273", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PNE8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNE8" } ], "pmid": "" }, { "name": "positive regulation of insulin secretion involved in cellular response to glucose stimulus", "id": "GO:0035774", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035774", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PNE8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNE8" } ], "pmid": "" }, { "name": "regulation of cytosolic calcium ion concentration", "id": "GO:0051480", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051480", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PNE8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNE8" } ], "pmid": "" }, { "name": "positive regulation of synaptic plasticity", "id": "GO:0031915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031915", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PNE8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNE8" } ], "pmid": "" }, { "name": "cellular response to morphine", "id": "GO:0071315", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071315", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PNE8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNE8" } ], "pmid": "" }, { "name": "positive regulation of long-term synaptic depression", "id": "GO:1900454", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900454", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PNE8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNE8" } ], "pmid": "" }, { "name": "glucose mediated signaling pathway", "id": "GO:0010255", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010255", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PNE8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNE8" } ], "pmid": "" }, { "name": "regulation of cellular response to stress", "id": "GO:0080135", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0080135", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PNE8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNE8" } ], "pmid": "" }, { "name": "neuroinflammatory response", "id": "GO:0150076", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0150076", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PNE8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNE8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1060, "end_pos": 1062, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1205, "end_pos": 1207, "annotation": "n_glycosylation_sequon" }, { "start_pos": 19, "end_pos": 21, "annotation": "n_glycosylation_sequon" }, { "start_pos": 400, "end_pos": 402, "annotation": "n_glycosylation_sequon" }, { "start_pos": 413, "end_pos": 415, "annotation": "n_glycosylation_sequon" }, { "start_pos": 767, "end_pos": 769, "annotation": "n_glycosylation_sequon" }, { "start_pos": 805, "end_pos": 807, "annotation": "n_glycosylation_sequon" }, { "start_pos": 809, "end_pos": 811, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "15389", "name": "", "equation": "ATP = 3',5'-cyclic AMP + diphosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A1D5PNE8-1", "A0A8V0XY43-1", "A0A8V0Y1I5-1", "F1NP57-1", "A0A1D5P0J0-1", "A0A8V0ZXY7-1", "A0A8V0ZZF3-1", "E1BX91-1", "Q9DGG6-1" ], "evidence": [ { "id": "15389", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/15389" } ] }, { "id": "R-GGA-111930", "name": "Adenylate cyclase produces cAMP", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1NP57-1", "A0A1D5P0J0-1", "A0A8V0XY43-1", "A0A8V0Y1I5-1", "A0A8V0ZXY7-1", "A0A8V0ZZF3-1", "E1BX91-1", "A0A1D5PNE8-1" ], "evidence": [ { "id": "R-GGA-111930", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-111930" } ] }, { "id": "R-GGA-170666", "name": "Adenylate cyclase increases the GTPase activity of G alpha-olf", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1NP57-1", "A0A1D5P0J0-1", "A0A8V0XY43-1", "A0A8V0Y1I5-1", "A0A8V0ZXY7-1", "A0A8V0ZZF3-1", "E1BX91-1", "A0A1D5PNE8-1" ], "evidence": [ { "id": "R-GGA-170666", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-170666" } ] }, { "id": "R-GGA-170671", "name": "G alpha-olf:GTP binds to Gi alpha1:GTP:adenylate cyclase complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1NP57-1", "A0A1D5P0J0-1", "A0A8V0XY43-1", "A0A8V0Y1I5-1", "A0A8V0ZXY7-1", "A0A8V0ZZF3-1", "E1BX91-1", "A0A1D5PNE8-1" ], "evidence": [ { "id": "R-GGA-170671", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-170671" } ] }, { "id": "R-GGA-170672", "name": "Galpha-olf:GTP binds to adenylate cyclase and activates it", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1NP57-1", "A0A1D5P0J0-1", "A0A8V0XY43-1", "A0A8V0Y1I5-1", "A0A8V0ZXY7-1", "A0A8V0ZZF3-1", "E1BX91-1", "A0A1D5PNE8-1" ], "evidence": [ { "id": "R-GGA-170672", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-170672" } ] }, { "id": "R-GGA-170674", "name": "Dissociation of the Gi alpha:G olf complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1NP57-1", "A0A1D5P0J0-1", "A0A8V0XY43-1", "A0A8V0Y1I5-1", "A0A8V0ZXY7-1", "A0A8V0ZZF3-1", "E1BX91-1", "A0A1D5PNE8-1" ], "evidence": [ { "id": "R-GGA-170674", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-170674" } ] }, { "id": "R-GGA-170676", "name": "Adenylate cyclase converts ATP into cyclic AMP", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1NP57-1", "A0A1D5P0J0-1", "A0A8V0XY43-1", "A0A8V0Y1I5-1", "A0A8V0ZXY7-1", "A0A8V0ZZF3-1", "E1BX91-1", "A0A1D5PNE8-1" ], "evidence": [ { "id": "R-GGA-170676", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-170676" } ] }, { "id": "R-GGA-170677", "name": "The G alpha-olf:GDP:Adenylate cyclase complex dissociates", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1NP57-1", "A0A1D5P0J0-1", "A0A8V0XY43-1", "A0A8V0Y1I5-1", "A0A8V0ZXY7-1", "A0A8V0ZZF3-1", "E1BX91-1", "A0A1D5PNE8-1" ], "evidence": [ { "id": "R-GGA-170677", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-170677" } ] }, { "id": "R-GGA-170685", "name": "Adenylaye cyclase increases the GTPase activity of G alpha-olf", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1NP57-1", "A0A1D5P0J0-1", "A0A8V0XY43-1", "A0A8V0Y1I5-1", "A0A8V0ZXY7-1", "A0A8V0ZZF3-1", "E1BX91-1", "A0A1D5PNE8-1" ], "evidence": [ { "id": "R-GGA-170685", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-170685" } ] }, { "id": "R-GGA-170686", "name": "Adenylate cyclase increases the GTPase activity of Gi alpha", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1NP57-1", "A0A1D5P0J0-1", "A0A8V0XY43-1", "A0A8V0Y1I5-1", "A0A8V0ZXY7-1", "A0A8V0ZZF3-1", "E1BX91-1", "A0A1D5PNE8-1" ], "evidence": [ { "id": "R-GGA-170686", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-170686" } ] }, { "id": "R-GGA-392064", "name": "G alpha (z) inhibits adenylate cyclase", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1NP57-1", "A0A1D5P0J0-1", "A0A8V0XY43-1", "A0A8V0Y1I5-1", "A0A8V0ZXY7-1", "A0A8V0ZZF3-1", "E1BX91-1", "A0A1D5PNE8-1" ], "evidence": [ { "id": "R-GGA-392064", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-392064" } ] }, { "id": "R-GGA-5610727", "name": "GPR161 promotes cAMP production in a G alpha(s)-dependent manner", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1NP57-1", "A0A1D5P0J0-1", "A0A8V0XY43-1", "A0A8V0Y1I5-1", "A0A8V0ZXY7-1", "A0A8V0ZZF3-1", "E1BX91-1", "A0A1D5PNE8-1" ], "evidence": [ { "id": "R-GGA-5610727", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5610727" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5P0J0", "gene_name": "ADCY5", "activity": [ { "ec_number": "4.6.1.1", "activity": "ATP = 3',5'-cyclic AMP + diphosphate.", "evidence": [ { "id": "A0A1D5P0J0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P0J0" } ] }, { "ec_number": "4.6.1.1", "activity": "", "evidence": [ { "id": "A0A1D5P0J0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P0J0" } ] } ] }, { "uniprot_ac": "A0A1D5PNE8", "gene_name": "ADCY8", "activity": [ { "ec_number": "4.6.1.1", "activity": "ATP = 3',5'-cyclic AMP + diphosphate.", "evidence": [ { "id": "A0A1D5PNE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNE8" } ] }, { "ec_number": "4.6.1.1", "activity": "", "evidence": [ { "id": "A0A1D5PNE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNE8" } ] } ] }, { "uniprot_ac": "A0A8V0XY43", "gene_name": "ADCY1", "activity": [ { "ec_number": "4.6.1.1", "activity": "ATP = 3',5'-cyclic AMP + diphosphate.", "evidence": [ { "id": "A0A8V0XY43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XY43" } ] }, { "ec_number": "4.6.1.1", "activity": "", "evidence": [ { "id": "A0A8V0XY43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XY43" } ] } ] }, { "uniprot_ac": "A0A8V0Y1I5", "gene_name": "ADCY3", "activity": [ { "ec_number": "4.6.1.1", "activity": "ATP = 3',5'-cyclic AMP + diphosphate.", "evidence": [ { "id": "A0A8V0Y1I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y1I5" } ] }, { "ec_number": "4.6.1.1", "activity": "", "evidence": [ { "id": "A0A8V0Y1I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y1I5" } ] } ] }, { "uniprot_ac": "A0A8V0ZXY7", "gene_name": "ADCY6", "activity": [ { "ec_number": "4.6.1.1", "activity": "ATP = 3',5'-cyclic AMP + diphosphate.", "evidence": [ { "id": "A0A8V0ZXY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXY7" } ] }, { "ec_number": "4.6.1.1", "activity": "", "evidence": [ { "id": "A0A8V0ZXY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXY7" } ] } ] }, { "uniprot_ac": "A0A8V0ZZF3", "gene_name": "ADCY7", "activity": [ { "ec_number": "4.6.1.1", "activity": "ATP = 3',5'-cyclic AMP + diphosphate.", "evidence": [ { "id": "A0A8V0ZZF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZF3" } ] }, { "ec_number": "4.6.1.1", "activity": "", "evidence": [ { "id": "A0A8V0ZZF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZF3" } ] } ] }, { "uniprot_ac": "E1BX91", "gene_name": "ADCY2", "activity": [ { "ec_number": "4.6.1.1", "activity": "ATP = 3',5'-cyclic AMP + diphosphate.", "evidence": [ { "id": "E1BX91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BX91" } ] }, { "ec_number": "4.6.1.1", "activity": "", "evidence": [ { "id": "E1BX91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BX91" } ] } ] }, { "uniprot_ac": "F1NP57", "gene_name": "ADCY9", "activity": [ { "ec_number": "4.6.1.1", "activity": "ATP = 3',5'-cyclic AMP + diphosphate.", "evidence": [ { "id": "F1NP57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NP57" } ] }, { "ec_number": "4.6.1.1", "activity": "", "evidence": [ { "id": "F1NP57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NP57" } ] } ] }, { "uniprot_ac": "Q9DGG6", "gene_name": "ADCY9", "activity": [ { "ec_number": "4.6.1.1", "activity": "ATP = 3',5'-cyclic AMP + diphosphate.", "evidence": [ { "id": "Q9DGG6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9DGG6" } ] }, { "ec_number": "4.6.1.1", "activity": "", "evidence": [ { "id": "Q9DGG6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9DGG6" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5PNE8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1240, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5PNE8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5PNE8" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "4.6.1.1", "ec_name": "ATP = 3',5'-cyclic AMP + diphosphate.", "evidence": [ { "id": "4.6.1.1", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:4.6.1.1" }, { "id": "4.6.1.1", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=4.6.1.1" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1060, "end_pos": 1062 }, { "start_pos": 1205, "end_pos": 1207 }, { "start_pos": 19, "end_pos": 21 }, { "start_pos": 400, "end_pos": 402 }, { "start_pos": 413, "end_pos": 415 }, { "start_pos": 767, "end_pos": 769 }, { "start_pos": 805, "end_pos": 807 }, { "start_pos": 809, "end_pos": 811 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": 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DNA/RNA helicase DHX36", "type": "synonym", "evidence": [ { "id": "XP_015147310", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015147310" } ] }, { "name": "DEAD/H box polypeptide 36", "type": "synonym", "evidence": [ { "id": "A0A1D5PHB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PHB6/entry#names_and_taxonomy" } ] }, { "name": "MLE-like protein 1", "type": "synonym", "evidence": [ { "id": "A0A1D5PHB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PHB6/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052540.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015147310", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015147310" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PHB6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PHB6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "DHX36", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PHB6", "locus": { "chromosome": "9", "start_pos": 22912794, "end_pos": 22895415, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010001462", "url": "https://www.ensembl.org/id/ENSGALG00010001462" } ] } } ], "crossref": [ { "id": "A0A1D5PHB6", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PHB6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000043082", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000043082", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd17981", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17981", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18791", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18791", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "425032", "url": "https://www.ncbi.nlm.nih.gov/gene/425032", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001650", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001650", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002464", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002464", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007502", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007502", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011545", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011545", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011709", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011709", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014001", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014001", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR059023", "url": "https://www.ebi.ac.uk/interpro/entry/IPR059023", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:425032", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:425032", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WLQSDKH", "url": "https://omabrowser.org/oma/group/WLQSDKH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PHB6", "url": "https://www.orthodb.org/?gene=A0A1D5PHB6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XBB6", "url": "https://www.orthodb.org/?gene=A0A8V0XBB6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR18934", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18934", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR18934:SF237", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18934:SF237", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00270", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00270", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00271", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00271", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF04408", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04408", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07717", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07717", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21010", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21010", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF26026", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26026", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-3134963", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3134963", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015147310", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015147310", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "13065", "url": "https://www.rhea-db.org/rhea/13065", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A1D5PHB6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PHB6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PHB6-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PHB6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XBB6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XBB6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XBB6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XBB6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSYEQRRDWGRGRGRGGDGGSSAASSGGGGHGGRGGGRGRHPSHLKGREIGLWYARKQGQKSKETDRQQRAVVRMDERREEQIVQLLNAVQPRAEKEQEAMSWWSGDEEGHVPEQPPKVKPGAEKAEKAPVKRRPILQKTFLDQDVEYLFEKNDQDADLDEQLKEDLRKKKSDPRYIEMQRFREKLPSYGMRQELVNLINNNRVTVISGETGCGKTTQVTQFILDDYIERGKGSTCRIVCTQPRRISAISVAERVAAERAEACGNGKSTGYQIRLQSRLPRKQGSILYCTTGIVLQWLQSDKHLSSISHVVLDEIHERNLQSDVLMSIIKDLLNVRLDLKVILMSATLNAEKFSEYFDNCPMIHIPGFTFPVVEYLLEDVIEKLRYTPENTDRRPRWKKGFMQGHISRPEKEEKEEIYRERWPEYLRQLRGRYSAGTIDALEMMDDDKVDLDLIAALIRHIVLEEEDGAILVFLPGWDNISTLHDLLMSQVMFKSDRFIIIPLHSLMPTVNQTQVFKKTPPGVRKIVIATNIAETSITIDDVVFVIDGGKIKETHFDTQNNISTMAAEWVSKANAKQRKGRAGRVQPGHCYHLYNGLRASLLDDYQLPEILRTPLEELCLQIKILKLGGIAYFLSKLMDPPSRDAVMLAINHLMELNALDRQEELTPLGVHLARLPVEPHIGKMILFGALFCCLDPVLTIAASLSFKDPFVIPLGKEKVADARRKELSKNTKSDHLTVVNAFTGWEETRRRGFRTEKDYCWEYFLSPNTLQMLHNMKGQFAEHLLAAGFVNSRDPKDPKSNTNSDNEKLLKAVICAGLYPKVAKIRPSFSKKRKMVKVCTKTDGTVNIHPKSVNVEETEFHYNWLVYHLKMRTSSIYLYDCTEVSPYCLLFFGGDISIQKDKDQDTIAVDEWIVFQSPARIAHLVKNLRQELDDLLQEKIENPHPVDWNDTKSRDTAVLTAIIDLITTQENESARNYAPRFQSERCS", "length": 987, "header": "tr|A0A1D5PHB6-1|A0A1D5PHB6_CHICK Isoform 1 of ATP-dependent DNA/RNA helicase DHX36 OS=Gallus gallus OX=9031 GN=DHX36 PE=1 SV=1 CANONICAL=A0A1D5PHB6-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PHB6-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PHB6/entry#A0A1D5PHB6-1", "sequence": { "sequence": "MSYEQRRDWGRGRGRGGDGGSSAASSGGGGHGGRGGGRGRHPSHLKGREIGLWYARKQGQKSKETDRQQRAVVRMDERREEQIVQLLNAVQPRAEKEQEAMSWWSGDEEGHVPEQPPKVKPGAEKAEKAPVKRRPILQKTFLDQDVEYLFEKNDQDADLDEQLKEDLRKKKSDPRYIEMQRFREKLPSYGMRQELVNLINNNRVTVISGETGCGKTTQVTQFILDDYIERGKGSTCRIVCTQPRRISAISVAERVAAERAEACGNGKSTGYQIRLQSRLPRKQGSILYCTTGIVLQWLQSDKHLSSISHVVLDEIHERNLQSDVLMSIIKDLLNVRLDLKVILMSATLNAEKFSEYFDNCPMIHIPGFTFPVVEYLLEDVIEKLRYTPENTDRRPRWKKGFMQGHISRPEKEEKEEIYRERWPEYLRQLRGRYSAGTIDALEMMDDDKVDLDLIAALIRHIVLEEEDGAILVFLPGWDNISTLHDLLMSQVMFKSDRFIIIPLHSLMPTVNQTQVFKKTPPGVRKIVIATNIAETSITIDDVVFVIDGGKIKETHFDTQNNISTMAAEWVSKANAKQRKGRAGRVQPGHCYHLYNGLRASLLDDYQLPEILRTPLEELCLQIKILKLGGIAYFLSKLMDPPSRDAVMLAINHLMELNALDRQEELTPLGVHLARLPVEPHIGKMILFGALFCCLDPVLTIAASLSFKDPFVIPLGKEKVADARRKELSKNTKSDHLTVVNAFTGWEETRRRGFRTEKDYCWEYFLSPNTLQMLHNMKGQFAEHLLAAGFVNSRDPKDPKSNTNSDNEKLLKAVICAGLYPKVAKIRPSFSKKRKMVKVCTKTDGTVNIHPKSVNVEETEFHYNWLVYHLKMRTSSIYLYDCTEVSPYCLLFFGGDISIQKDKDQDTIAVDEWIVFQSPARIAHLVKNLRQELDDLLQEKIENPHPVDWNDTKSRDTAVLTAIIDLITTQENESARNYAPRFQSERCS", "length": 987, "header": "tr|A0A1D5PHB6-1|A0A1D5PHB6_CHICK Isoform 1 of ATP-dependent DNA/RNA helicase DHX36 OS=Gallus gallus OX=9031 GN=DHX36 PE=1 SV=1 CANONICAL=A0A1D5PHB6-1" }, "locus": { "chromosome": "9", "start_pos": 22912382, "end_pos": 22895429, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010003384.1", "url": "https://www.ensembl.org/id/ENSGALT00010003384.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010001827.1", "url": "https://www.ensembl.org/id/ENSGALP00010001827.1" } ] } }, { "isoform_ac": "A0A8V0XBB6-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PHB6/entry#A0A8V0XBB6-1", "sequence": { "sequence": "MSWWSGDEEGHVPEQPPKVKPGAEKAEKAPVKRRPILQKTFLDQDVEYLFEKNDQDADLDEQLKEDLRKKKSDPRYIEMQRFREKLPSYGMRQELVNLINNNRVTVISGETGCGKTTQVTQFILDDYIERGKGSTCRIVCTQPRRISAISVAERVAAERAEACGNGKSTGYQIRLQSRLPRKQGSILYCTTGIVLQWLQSDKHLSSISHVVLDEIHERNLQSDVLMSIIKDLLNVRLDLKVILMSATLNAEKFSEYFDNCPMIHIPGFTFPVVEYLLEDVIEKLRYTPENTDRRPRWKKGFMQGHISRPEKEEKEEIYRERWPEYLRQLRGRYSAGTIDALEMMDDDKVDLDLIAALIRHIVLEEEDGAILVFLPGWDNISTLHDLLMSQVMFKSDRFIIIPLHSLMPTVNQTQVFKKTPPGVRKIVIATNIAETSITIDDVVFVIDGGKIKETHFDTQNNISTMAAEWVSKANAKQRKGRAGRVQPGHCYHLYNGLRASLLDDYQLPEILRTPLEELCLQIKILKLGGIAYFLSKLMDPPSRDAVMLAINHLMELNALDRQEELTPLGVHLARLPVEPHIGKMILFGALFCCLDPVLTIAASLSFKDPFTRRRGFRTEKDYCWEYFLSPNTLQMLHNMKGQFAEHLLAAGFVNSRDPKDPKSNTNSDNEKLLKAVICAGLYPKVAKIRPSFSKKRKMVKVCTKTDGTVNIHPKSVNVEETEFHYNWLVYHLKMRTSSIYLYDCTEVSPYCLLFFGGDISIQKDKDQDTIAVDEWIVFQSPARIAHLVKNLRQELDDLLQEKIENPHPVDWNDTKSRDTAVLTAIIDLITTQENESARNYAPRFQSERCS", "length": 850, "header": "tr|A0A8V0XBB6-1|A0A1D5PHB6_CHICK Computationally mapped isoform of ATP-dependent DNA/RNA helicase DHX36 OS=Gallus gallus OX=9031 GN=DHX36 PE=1 SV=1 CANONICAL=A0A1D5PHB6-1" }, "locus": { "chromosome": "9", "start_pos": 22912382, "end_pos": 22895826, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010003382.1", "url": "https://www.ensembl.org/id/ENSGALT00010003382.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010001825.1", "url": "https://www.ensembl.org/id/ENSGALP00010001825.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:425032", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:425032", "resource": "KEGG Pathway" }, { "id": "R-GGA-3134963", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3134963", "resource": "Reactome", "description": "DEx/H-box helicases activate type I IFN and inflammatory cytokines production" } ], "orthologs": [ { "uniprot_canonical_ac": "D4A2Z8-1", "protein_name": "ATP-dependent DNA/RNA helicase DHX36", "gene_name": "Dhx36", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSYDYHQSWSRDGGPRGSGQGSGGGGGGSRGSGGGGGGRGGRGRHPAHLKGREIGLWYAKKQTQKNKEAERQERAVVHMDERREEQIVQLLNSVQAKNDKDSEAQISWFAPEDHGYGTEVSSEKKINSEKKLDNQEKKLLNQEKKTYRITDKSYIDRDSEYLLQQNEPNLGLDQQLLEDLQKKKTDPRYIEMQRFRKKLPSYGMQKELVNLINNHQVTVISGETGCGKTTQVTQFILDNYIERGIGSACRIVCTQPRRISAISVAERVAAERAESCGNGNSTGYQIRLQSRLPRKQGSILYCTTGIILQWLQSDSRLSSVSHIVLDEIHERNLQSDVLMTVIKDLLHFRSDLKVILMSATLNAEKFSEYFGNCPMIHIPGFTFPVVEYLLEDIIEKIRYFPEQKEHRSQFKRGFMQGHVNRQEKEEKEAIYKERWPAYIKELQTRYSASTIDVLEMMDDDKVDLNLIAALIRYIVLEEEDGAILVFLPGWDNISTLHDLLMSQVMFKSDRFLIIPLHSLMPTVNQTQVFKKTPPGVRKIVIATNIAETSITIDDVVYVIDGGKIKETHFDTQNNISTMSAEWVSKANAKQRKGRAGRVQPGHCYHLYNGLRASLLDDYQLPEILRTPLEELCLQIKILRLGGIAYFLSRLMDPPSDEAVVLSIKHLMELSALDKQEELTPLGVHLARLPVEPHIGKMILFGALFCCLDPVLTIAASLSFKDPFVIPLGKEKIADARRKELAKETRSDHLTVVNAFEGWEEAKRRGFRYEKDYCWEYFLSSNTLQMLHNMKGQFAEHLLGAGFVSSRSPKDPKANINSDNEKIIKAVICAGLYPKVAKIRLNLGKKRKMVKVHTKSDGLVSIHPKSVNVEQTDFHYNWLIYHLKMRTSSIYLYDCTEVSPYCLLFFGGDISIQKDKDQEIIAVDEWIVFQSPERIAHLVKGLRKELDILLQEKIECPHPVDWNDTKSRDCAVLSAILDLIKTQEKAIPRNLPPRSQDGYYS", "length": 1000 }, "evidence": [ { "id": "A0A1D5PHB6", "url": "https://omabrowser.org/oma/group/A0A1D5PHB6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q05B79-1", "protein_name": "ATP-dependent DNA/RNA helicase DHX36", "gene_name": "DHX36", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSYDYHQNWGRDGGPRSSGGGYGGSYGGSHGGGHGGNRGSGGGGGGGGGRGGRGRHPGHLKGREIGLWYAKKQGQKNKEAERQERAVVHMDERREEQIVQLLHSVQTKNDKDEEAQISWFAPEDHGYGTEAPAENKPNSVKNVEHQEKKMINQEKRPFRIRDKYIDRDSEYLLQENEPDATLDQQLLEDLQKKKTDLRYIEMQRFREKLPSYGMQKELVNMIDNHQVTVISGETGCGKTTQVTQFILDNYIERGKGSACRIVCTQPRRISAISVAERVAAERAESCGNGNSTGYQIRLQSRLPRKQGSILYCTTGIILQWLQSDPHLSSVSHIVLDEIHERNLQSDVLMTVVKDLLSYRPDLKVVLMSATLNAEKFSEYFGNCPMIHIPGFTFPVVEYLLEDIIEKIRYVPEQKEHRSQFKKGFMQGHVNRQEKEEKEAIYKERWPGYLRELRQRYSASTVDVVEMMDDEKVDLNLIAALIRYIVLEEEDGAILVFLPGWDNISTLHDLLMSQVMFKSDKFIIIPLHSLMPTVNQTQVFKRTPPGVRKIVIATNIAETSITIDDVVYVIDGGKIKETHFDTQNNISTMSAEWVSKANAKQRKGRAGRVQPGHCYHLYNSLRASLLDDYQLPEILRTPLEELCLQIKILRLGGIAHFLSRLMDPPSNEAVLLSIKHLMELNALDKQEELTPLGVHLARLPVEPHIGKMILFGALFCCLDPVLTIAASLSFKDPFVIPLGKEKVADARRKELAKDTKSDHLTVVNAFKGWEKAKQRGFRYEKDYCWEYFLSSNTLQMLHNMKGQFAEHLLGAGFVSSRNPQDPESNINSDNEKIIKAVICAGLYPKVAKIRLNLGKKRKMVKVYTKTDGVVAIHPKSVNVEQTEFNYNWLIYHLKMRTSSIYLYDCTEVSPYCLLFFGGDISIQKDNDQETIAVDEWIIFQSPARIAHLVKELRKELDILLQEKIESPHPVDWKDTKSRDCAVLSAIIDLIKTQEKATPRNLPPRFQDGYYS", "length": 1010 }, "evidence": [ { "id": "A0A1D5PHB6", "url": "https://omabrowser.org/oma/group/A0A1D5PHB6/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8VHK9-1", "protein_name": "ATP-dependent DNA/RNA helicase DHX36", "gene_name": "Dhx36", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSYDYHQSWSRDGGPRGSGQGSSGGGGGGSRGSGGGGGGRGGRGRHPAHLKGREIGLWYAKKQTQKNKEAERQERAVVHMDERREEQIVQLLNSVQAKTDKDSEAQISWFAPEDHGYGTEVSSEKKINSEKKLDNQEKKLLNQEKKTFRITDKSYIDRDSEYLLQENEPNLSLDQHLLEDLQRKKTDPRYIEMQRFRKKLPSYGMQKELVNLINNHQVTVISGETGCGKTTQVTQFILDNYIERGKGSACRIVCTQPRRISAISVAERVATERAESCGNGNSTGYQIRLQSRLPRKQGSILYCTTGIILQWLQSDSRLSSVSHIVLDEIHERNLQSDVLMTVIKDLLHFRSDLKVILMSATLNAEKFSEYFGNCPMIHIPGFTFPVVEYLLEDIIEKIRYVPDQKEHRSQFKRGFMQGHVNRQEKEEKEAIYKERWPAYIKELRTRYSASTVDVLQMMDDDKVDLNLIAALIRYIVLEEEDGAILVFLPGWDNISTLHDLLMSQVMFKSDKFLIIPLHSLMPTVNQTQVFKKTPPGVRKIVIATNIAETSITIDDVVYVIDGGKIKETHFDTQNNISTMSAEWVSKANAKQRKGRAGRVQPGHCYHLYNGLRASLLDDYQLPEILRTPLEELCLQIKILRLGGIAYFLSRLMDPPSNEAVVLSIKHLMELSALDKQEELTPLGVHLARLPVEPHIGKMILFGALFCCLDPVLTIAASLSFKDPFVIPLGKEKIADARRKELAKETRSDHLTVVNAFEGWEEAKRRGFRYEKDYCWEYFLSSNTLQMLHNMKGQFAEHLLGAGFVSSRSPKDPKANINSDNEKIIKAVICAGLYPKVAKIRLNLGKKRKMVKVHTKSDGLVSIHPKSVNVEQTDFHYNWLIYHLKMRTSSIYLYDCTEVSPYCLLFFGGDISIQKDKDQEIIAVDEWIVFQSPERIAHLVKGLRKELDSLLQEKIESPHPVDWDDTKSRDCAVLSAILDLIKTQEKATPRNLPPRSQDGYYS", "length": 1001 }, "evidence": [ { "id": "A0A1D5PHB6", "url": "https://omabrowser.org/oma/group/A0A1D5PHB6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9H2U1-1", "protein_name": "ATP-dependent DNA/RNA helicase DHX36", "gene_name": "DHX36", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSYDYHQNWGRDGGPRSSGGGYGGGPAGGHGGNRGSGGGGGGGGGGRGGRGRHPGHLKGREIGMWYAKKQGQKNKEAERQERAVVHMDERREEQIVQLLNSVQAKNDKESEAQISWFAPEDHGYGTEVSTKNTPCSENKLDIQEKKLINQEKKMFRIRNRSYIDRDSEYLLQENEPDGTLDQKLLEDLQKKKNDLRYIEMQHFREKLPSYGMQKELVNLIDNHQVTVISGETGCGKTTQVTQFILDNYIERGKGSACRIVCTQPRRISAISVAERVAAERAESCGSGNSTGYQIRLQSRLPRKQGSILYCTTGIILQWLQSDPYLSSVSHIVLDEIHERNLQSDVLMTVVKDLLNFRSDLKVILMSATLNAEKFSEYFGNCPMIHIPGFTFPVVEYLLEDVIEKIRYVPEQKEHRSQFKRGFMQGHVNRQEKEEKEAIYKERWPDYVRELRRRYSASTVDVIEMMEDDKVDLNLIVALIRYIVLEEEDGAILVFLPGWDNISTLHDLLMSQVMFKSDKFLIIPLHSLMPTVNQTQVFKRTPPGVRKIVIATNIAETSITIDDVVYVIDGGKIKETHFDTQNNISTMSAEWVSKANAKQRKGRAGRVQPGHCYHLYNGLRASLLDDYQLPEILRTPLEELCLQIKILRLGGIAYFLSRLMDPPSNEAVLLSIRHLMELNALDKQEELTPLGVHLARLPVEPHIGKMILFGALFCCLDPVLTIAASLSFKDPFVIPLGKEKIADARRKELAKDTRSDHLTVVNAFEGWEEARRRGFRYEKDYCWEYFLSSNTLQMLHNMKGQFAEHLLGAGFVSSRNPKDPESNINSDNEKIIKAVICAGLYPKVAKIRLNLGKKRKMVKVYTKTDGLVAVHPKSVNVEQTDFHYNWLIYHLKMRTSSIYLYDCTEVSPYCLLFFGGDISIQKDNDQETIAVDEWIVFQSPARIAHLVKELRKELDILLQEKIESPHPVDWNDTKSRDCAVLSAIIDLIKTQEKATPRNFPPRFQDGYYS", "length": 1008 }, "evidence": [ { "id": "A0A1D5PHB6", "url": "https://omabrowser.org/oma/group/A0A1D5PHB6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 25, "go_terms": [ { "name": "positive regulation of transcription initiation by RNA polymerase II", "id": "GO:0060261", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060261", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PHB6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PHB6" } ], "pmid": "" }, { "name": "positive regulation of interferon-alpha production", "id": "GO:0032727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032727", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PHB6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PHB6" } ], "pmid": "" }, { "name": "positive regulation of cytoplasmic translation", "id": "GO:2000767", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000767", "evidence": [ { 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"F1NN44-1", "P08110-1", "F1NTD6-1", "A0A8V0Z655-1", "A0A8V1ALH0-1", "B6ZLK2-1", "A0A8V0YLC1-1", "Q06A37-1", "A0A8V0YGQ1-1", "A0A1D5PD32-1", "Q6EE31-1", "A0A8V0XX13-1", "A0A8V0YCY8-1", "A0A8V0Z5P2-1", "A0A8V0ZUQ0-1", "A0A8V1ADZ7-1", "A0A8V0XG98-1", "A0A8V0ZR10-1", "A0A8V1AFJ9-1", "Q5ZJ54-1", "Q5ZJK8-1", "A0A8V0Y005-1", "A0A8V0YAA4-1", "A0A8V0XGV3-1", "A0A8V0X600-1", "Q5ZM73-1", "Q5ZM83-1", "A0A8V0ZUR5-1", "A0A8V0ZE45-1", "A0A8V0ZEN5-1", "F1NA92-1", "A0A8V0ZTR5-1", "A0A8V1A7P4-1", "A0A8V1AIK2-1", "F1P5C0-1", "A0A8V0XHD1-1", "A0A8V0X655-1", "A0A8V0XMP8-1", "A0A8V0YUC5-1", "A0A8V0Z1F9-1", "A0A8V0Z659-1", "A0A8V0YRH6-1", "A0A8V0ZS56-1", "I0IUP3-1", "I0IUP4-1", "O93257-1", "O93295-1", "A0A8V0ZIP8-1", "Q9DG67-1", "P37383-1", "Q5ZKG3-1", "P79784-1", "A0A1D5PS27-1", "A0A1D5PVS9-1", "A0A8V1AE46-1", "A0A8V1A8Y2-1", "A0A8V1AKU6-1", "O12944-1", "A0A8V0YQS3-1", "A0A8V0Z2M8-1" ], "evidence": [ { "id": "13065", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/13065" } ] }, { "id": "R-GGA-3134953", "name": "DHX36 or DHX9 binds MyD88", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A1D5PHB6-1" ], "evidence": [ { "id": "R-GGA-3134953", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3134953" } ] }, { "id": "R-GGA-3134962", "name": "DHX36 binds DNA", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A1D5PHB6-1" ], "evidence": [ { "id": "R-GGA-3134962", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3134962" } ] }, { "id": "R-GGA-9604487", "name": "p-IRF7:p-IRF7 translocates to the nucleus", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nuclear envelope", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A1D5PHB6-1" ], "evidence": [ { "id": "R-GGA-9604487", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9604487" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5NTY5", "gene_name": "LOC430766", "activity": [ { "ec_number": "3.6.4.6", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5NTY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NTY5" } ] }, { "ec_number": "3.6.4.6", "activity": "", "evidence": [ { "id": "A0A1D5NTY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NTY5" } ] } ] }, { "uniprot_ac": "A0A1D5P5I0", "gene_name": "IFIH1", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5P5I0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P5I0" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A1D5P5I0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P5I0" } ] } ] }, { "uniprot_ac": "A0A1D5PD32", "gene_name": "DDX17", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5PD32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PD32" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A1D5PD32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PD32" } ] } ] }, { "uniprot_ac": "A0A1D5PHB6", "gene_name": "DHX36", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5PHB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PHB6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A1D5PHB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PHB6" } ] } ] }, { "uniprot_ac": "A0A1D5PIN7", "gene_name": "DHX30", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5PIN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PIN7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A1D5PIN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PIN7" } ] } ] }, { "uniprot_ac": "A0A1D5PRR9", "gene_name": "FANCM", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5PRR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRR9" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A1D5PRR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRR9" } ] } ] }, { "uniprot_ac": "A0A1D5PS27", "gene_name": "ENTPD2", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "A0A1D5PS27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PS27" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "A0A1D5PS27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PS27" } ] } ] }, { "uniprot_ac": "A0A1D5PVS9", "gene_name": "ENTPD3", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "A0A1D5PVS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PVS9" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "A0A1D5PVS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PVS9" } ] } ] }, { "uniprot_ac": "A0A3S5ZPN3", "gene_name": "DDX5", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3S5ZPN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPN3" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A3S5ZPN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPN3" } ] } ] }, { "uniprot_ac": "A0A8V0X600", "gene_name": "DDX43", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0X600", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X600" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0X600", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X600" } ] } ] }, { "uniprot_ac": "A0A8V0X655", "gene_name": "DHX32", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0X655", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X655" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0X655", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X655" } ] } ] }, { "uniprot_ac": "A0A8V0X9Y7", "gene_name": "CFTR", "activity": [ { "ec_number": "5.6.1.6", "activity": "ATP + H2O + closed Cl(-) channel = ADP + phosphate + open Cl(-) channel.", "evidence": [ { "id": "A0A8V0X9Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X9Y7" } ] }, { "ec_number": "5.6.1.6", "activity": "", "evidence": [ { "id": "A0A8V0X9Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X9Y7" } ] } ] }, { "uniprot_ac": "A0A8V0X9Z6", "gene_name": "MOV10L1", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0X9Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X9Z6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0X9Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X9Z6" } ] } ] }, { "uniprot_ac": "A0A8V0XEC4", "gene_name": "DDX10", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XEC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEC4" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0XEC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEC4" } ] } ] }, { "uniprot_ac": "A0A8V0XG98", "gene_name": "HELQ", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XG98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XG98" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A8V0XG98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XG98" } ] } ] }, { "uniprot_ac": "A0A8V0XGV3", "gene_name": "DDX3X", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XGV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XGV3" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0XGV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XGV3" } ] } ] }, { "uniprot_ac": "A0A8V0XHD1", "gene_name": "AQR", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XHD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XHD1" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0XHD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XHD1" } ] } ] }, { "uniprot_ac": "A0A8V0XI26", "gene_name": "DDX1", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XI26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XI26" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0XI26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XI26" } ] } ] }, { "uniprot_ac": "A0A8V0XJV9", "gene_name": "SPATA5", "activity": [ { "ec_number": "3.6.4.6", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XJV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJV9" } ] }, { "ec_number": "3.6.4.6", "activity": "", "evidence": [ { "id": "A0A8V0XJV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJV9" } ] }, { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XJV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJV9" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "A0A8V0XJV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJV9" } ] } ] }, { "uniprot_ac": "A0A8V0XLC7", "gene_name": "MCM4", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XLC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLC7" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0A8V0XLC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLC7" } ] } ] }, { "uniprot_ac": "A0A8V0XMP8", "gene_name": "ZGRF1", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "A0A8V0XMP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMP8" } ] }, { "ec_number": "5.6.2.3", "activity": "", "evidence": [ { "id": "A0A8V0XMP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMP8" } ] } ] }, { "uniprot_ac": "A0A8V0XT73", "gene_name": "FBXO18", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XT73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XT73" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A8V0XT73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XT73" } ] } ] }, { "uniprot_ac": "A0A8V0XX13", "gene_name": "LOC101748706", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XX13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XX13" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": 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"ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZEN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEN5" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0ZEN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEN5" } ] } ] }, { "uniprot_ac": "A0A8V0ZFN9", "gene_name": "DDX54", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZFN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFN9" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0ZFN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFN9" } ] } ] }, { "uniprot_ac": "A0A8V0ZIP8", "gene_name": "XRCC5", "activity": [ { "ec_number": "4.2.99.18", "activity": "2'-deoxyribonucleotide-(2'-deoxyribose 5'-phosphate)-2'-deoxyribonucleotide-DNA = a 3'-end 2'-deoxyribonucleotide-(2,3-dehydro-2,3-deoxyribose 5'-phosphate)-DNA + a 5'-end 5'-phospho-2'-deoxyribonucleoside-DNA + H(+).", "evidence": [ { "id": "A0A8V0ZIP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIP8" } ] }, { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZIP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIP8" } ] }, { "ec_number": "4.2.99.18", "activity": "", "evidence": [ { "id": "A0A8V0ZIP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIP8" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A8V0ZIP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIP8" } ] } ] }, { "uniprot_ac": "A0A8V0ZNU6", "gene_name": "DDX18", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZNU6", "database": "UniProtKB", "url": 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} ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0ZPM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPM1" } ] } ] }, { "uniprot_ac": "A0A8V0ZPN6", "gene_name": "INO80", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "A0A8V0ZPN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPN6" } ] } ] }, { "uniprot_ac": "A0A8V0ZR10", "gene_name": "PIF1", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "A0A8V0ZR10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR10" } ] }, { "ec_number": "5.6.2.3", "activity": "", "evidence": [ { "id": "A0A8V0ZR10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR10" } ] } ] }, { "uniprot_ac": "A0A8V0ZS56", "gene_name": "HFM1", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZS56", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS56" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A8V0ZS56", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS56" } ] } ] }, { "uniprot_ac": "A0A8V0ZTR5", "gene_name": "LOC423693", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZTR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTR5" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0ZTR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTR5" } ] } ] }, { "uniprot_ac": "A0A8V0ZU49", "gene_name": "DNA2", "activity": [ { "ec_number": "3.1.-.-", "activity": "", "evidence": [ { "id": "A0A8V0ZU49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU49" } ] }, { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZU49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU49" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0A8V0ZU49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU49" } ] } ] }, { "uniprot_ac": "A0A8V0ZUQ0", "gene_name": "DDX21", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZUQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUQ0" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0ZUQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUQ0" } ] } ] }, { "uniprot_ac": "A0A8V0ZUR5", "gene_name": "DDX6", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZUR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUR5" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0ZUR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUR5" } ] } ] }, { "uniprot_ac": "A0A8V0ZUT3", "gene_name": "DHX58", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZUT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUT3" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0ZUT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUT3" } ] } ] }, { "uniprot_ac": "A0A8V0ZVY2", "gene_name": "RTEL1", "activity": [ { "ec_number": "5.6.2.-", "activity": "", "evidence": [ { "id": "A0A8V0ZVY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVY2" } ] } ] }, { "uniprot_ac": "A0A8V0ZWH7", "gene_name": "DHX35", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZWH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWH7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0ZWH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWH7" } ] } ] }, { "uniprot_ac": "A0A8V0ZZF5", "gene_name": "DHX8", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZZF5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZF5" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0ZZF5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZF5" } ] } ] }, { "uniprot_ac": "A0A8V0ZZK3", "gene_name": "SUPV3L1", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZZK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZK3" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0ZZK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZK3" } ] } ] }, { "uniprot_ac": "A0A8V1A3M1", "gene_name": "DDX55", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1A3M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3M1" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V1A3M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3M1" } ] } ] }, { "uniprot_ac": "A0A8V1A4V3", "gene_name": "POLQ", "activity": [ { "ec_number": "2.7.7.7", "activity": "DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate.", "evidence": [ { "id": "A0A8V1A4V3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V3" } ] }, { "ec_number": "2.7.7.49", "activity": "DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate.", "evidence": [ { "id": "A0A8V1A4V3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V3" } ] }, { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1A4V3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V3" } ] }, { "ec_number": "2.7.7.7", "activity": "", "evidence": [ { "id": "A0A8V1A4V3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V3" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0A8V1A4V3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V3" } ] }, { "ec_number": "2.7.7.49", "activity": "", "evidence": [ { "id": "A0A8V1A4V3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V3" } ] } ] }, { "uniprot_ac": "A0A8V1A5D6", "gene_name": "DDX51", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1A5D6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5D6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V1A5D6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5D6" } ] } ] }, { "uniprot_ac": "A0A8V1A712", "gene_name": "", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1A712", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A712" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V1A712", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A712" } ] } ] }, { "uniprot_ac": "A0A8V1A7M6", "gene_name": "", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1A7M6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V1A7M6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M6" } ] } ] }, { "uniprot_ac": "A0A8V1A7P4", "gene_name": "DDX49", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1A7P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P4" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V1A7P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P4" } ] } ] }, { "uniprot_ac": "A0A8V1A8Y2", "gene_name": "ENTPD8", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "A0A8V1A8Y2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8Y2" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "A0A8V1A8Y2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8Y2" } ] } ] }, { "uniprot_ac": "A0A8V1ACD8", "gene_name": "NSF", "activity": [ { "ec_number": "3.6.4.6", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1ACD8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACD8" } ] }, { "ec_number": "3.6.4.6", "activity": "", "evidence": [ { "id": "A0A8V1ACD8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACD8" } ] } ] }, { "uniprot_ac": "A0A8V1ADZ7", "gene_name": "RHOT1", "activity": [ { "ec_number": "3.6.5.-", "activity": "", "evidence": [ { "id": "A0A8V1ADZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADZ7" } ] } ] }, { "uniprot_ac": "A0A8V1AE46", "gene_name": "ENTPD8L1", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "A0A8V1AE46", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE46" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "A0A8V1AE46", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE46" } ] } ] }, { "uniprot_ac": "A0A8V1AER6", "gene_name": "MOV10", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1AER6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AER6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V1AER6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AER6" } ] } ] }, { "uniprot_ac": "A0A8V1AFG8", "gene_name": "RECQL5", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1AFG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFG8" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A8V1AFG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFG8" } ] } ] }, { "uniprot_ac": "A0A8V1AFJ9", "gene_name": "MCM2", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1AFJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFJ9" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0A8V1AFJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFJ9" } ] } ] }, { "uniprot_ac": "A0A8V1AIK2", "gene_name": "DDX25", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1AIK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIK2" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V1AIK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIK2" } ] } ] }, { "uniprot_ac": "A0A8V1AJ43", "gene_name": "DHX40", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1AJ43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ43" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V1AJ43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ43" } ] } ] }, { "uniprot_ac": "A0A8V1AJY9", "gene_name": "DDX31", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1AJY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJY9" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": 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phosphate + 2 H(+).", "evidence": [ { "id": "O93295", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O93295" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "O93295", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O93295" } ] } ] }, { "uniprot_ac": "P08023", "gene_name": "ACTA2", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "P08023", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P08023" } ] } ] }, { "uniprot_ac": "P08110", "gene_name": "HSP90B1", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "P08110", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P08110" } ] } ] }, { "uniprot_ac": "P37383", "gene_name": "RAD51A", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "P37383", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P37383" } ] } ] }, { "uniprot_ac": "P53478", 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transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PIQ5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PIQ5" } ], "pmid": "" }, { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PIQ5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PIQ5" } ], "pmid": "" }, { "name": "negative regulation of canonical Wnt signaling pathway", "id": "GO:0090090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090090", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PIQ5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PIQ5" } ], "pmid": "" }, { "name": "response to insulin", "id": "GO:0032868", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032868", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PIQ5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PIQ5" } ], "pmid": "" }, { "name": "signal transduction in response to DNA damage", "id": "GO:0042770", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042770", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PIQ5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PIQ5" } ], "pmid": "" }, { "name": "positive regulation of reactive oxygen species metabolic process", "id": "GO:2000379", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000379", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PIQ5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PIQ5" } ], "pmid": "" }, { "name": "positive regulation of erythrocyte differentiation", "id": "GO:0045648", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045648", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PIQ5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PIQ5" } ], "pmid": "" }, { "name": "vascular endothelial growth factor receptor signaling pathway", "id": "GO:0048010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048010", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PIQ5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PIQ5" } ], "pmid": "" }, { "name": "bone development", "id": "GO:0060348", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060348", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PIQ5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PIQ5" } ], "pmid": "" }, { "name": "osteoblast differentiation", "id": "GO:0001649", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001649", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PIQ5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PIQ5" } ], "pmid": "" }, { "name": "positive regulation of myoblast fusion", "id": "GO:1901741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901741", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PIQ5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PIQ5" } ], "pmid": "" }, { "name": "cartilage condensation", "id": "GO:0001502", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001502", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PIQ5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PIQ5" } ], "pmid": "" }, { "name": "response to dietary excess", "id": "GO:0002021", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002021", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PIQ5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PIQ5" } ], "pmid": "" }, { "name": "tumor necrosis factor-mediated signaling pathway", "id": "GO:0033209", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033209", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PIQ5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PIQ5" } ], "pmid": "" }, { "name": "negative regulation of hippo signaling", "id": "GO:0035331", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035331", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PIQ5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PIQ5" } ], "pmid": "" }, { "name": "cellular response to vascular endothelial growth factor stimulus", "id": "GO:0035924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035924", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PIQ5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PIQ5" } ], "pmid": "" }, { "name": "stress-activated MAPK cascade", "id": "GO:0051403", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051403", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PIQ5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PIQ5" } ], "pmid": "" }, { "name": "cellular response to virus", "id": "GO:0098586", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098586", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PIQ5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PIQ5" } ], "pmid": "" }, { "name": "cellular response to ionizing radiation", "id": "GO:0071479", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071479", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PIQ5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PIQ5" } ], "pmid": "" }, { "name": "cellular response to lipoteichoic acid", "id": "GO:0071223", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071223", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PIQ5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PIQ5" } ], "pmid": "" }, { "name": "regulation of synaptic membrane adhesion", "id": "GO:0099179", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099179", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PIQ5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PIQ5" } ], "pmid": "" }, { "name": "regulation of cytokine production involved in inflammatory response", "id": "GO:1900015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900015", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PIQ5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PIQ5" } ], "pmid": "" }, { "name": "positive regulation of myoblast differentiation", "id": "GO:0045663", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045663", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PIQ5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PIQ5" } ], "pmid": "" }, { "name": "positive regulation of interleukin-12 production", "id": "GO:0032735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032735", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PIQ5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PIQ5" } ], "pmid": "" }, { "name": "p38MAPK cascade", "id": "GO:0038066", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038066", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PIQ5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PIQ5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PIQ5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PIQ5" } ], "pmid": "" }, { "name": "spindle pole", "id": "GO:0000922", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000922", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PIQ5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PIQ5" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PIQ5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PIQ5" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PIQ5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PIQ5" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PIQ5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PIQ5" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PIQ5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PIQ5" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PIQ5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PIQ5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "NFAT protein binding", "id": "GO:0051525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051525", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PIQ5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PIQ5" } ], "pmid": "" }, { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PIQ5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PIQ5" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PIQ5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PIQ5" } ], "pmid": "" }, { "name": "mitogen-activated protein kinase p38 binding", "id": "GO:0048273", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048273", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PIQ5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PIQ5" } ], "pmid": "" }, { "name": "protein phosphatase binding", "id": "GO:0019903", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019903", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PIQ5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PIQ5" } ], "pmid": "" }, { "name": "MAP kinase activity", "id": "GO:0004707", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004707", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PIQ5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PIQ5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 14, "end_pos": 16, "annotation": "n_glycosylation_sequon" }, { "start_pos": 201, "end_pos": 203, "annotation": "n_glycosylation_sequon" }, { "start_pos": 26, "end_pos": 28, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-GGA-168053", "name": "Phosphorylated MAPKs phosphorylate ATF-2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [ "R-GGA-450336" ], "output_participant_list": [ "R-GGA-450243" ], "enzyme_list": [ "A0A3Q2TY19-1", "P79996-1", "A0A8V1A4Q4-1", "A0A8V0XLV6-1", "A0A1D5PIQ5-1" ], "evidence": [ { "id": "R-GGA-168053", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-168053" } ] }, { "id": "R-GGA-187688", "name": "p38 MAPK phosphorylates MAPKAPK2, MAPKAPK3", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-GGA-187743" ], "output_participant_list": [ "R-GGA-187760" ], "enzyme_list": [ "F1NCY7-1", "A0A1D5PIQ5-1" ], "evidence": [ { "id": "R-GGA-187688", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-187688" } ] }, { "id": "R-GGA-198669", "name": "p38MAPK phosphorylates MSK1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [ "R-GGA-198657" ], "output_participant_list": [ "R-GGA-198683" ], "enzyme_list": [ "A0A1D5PIQ5-1", "Q5F3L1-1" ], "evidence": [ { "id": "R-GGA-198669", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-198669" } ] }, { "id": "R-GGA-3238999", "name": "Activated human MKK3/MKK6 phosphorylates p38 MAPK complexed with MAPKAPK5", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1NVF2-1", "A0A1D5PD64-1", "A0A8V1A4J8-1", "A0A1D5PIQ5-1" ], "evidence": [ { "id": "R-GGA-3238999", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3238999" } ] }, { "id": "R-GGA-3239019", "name": "Active p38 MAPK phosphorylates MAPKAPK5", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V1A4J8-1", "A0A1D5PIQ5-1" ], "evidence": [ { "id": "R-GGA-3239019", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3239019" } ] }, { "id": "R-GGA-428941", "name": "P2Y purinoceptor 1 activates MAP kinase p38 alpha", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-GGA-428933" ], "output_participant_list": [ "R-GGA-428935" ], "enzyme_list": [ "A0A1D5PIQ5-1" ], "evidence": [ { "id": "R-GGA-428941", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-428941" } ] }, { "id": "R-GGA-428961", "name": "Phosphorylation of cPLA2 by MAPK p38 alpha", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, endoplasmic reticulum membrane", "input_participant_list": [ "R-GGA-378502" ], "output_participant_list": [], "enzyme_list": [ "A0A1D5PIQ5-1" ], "evidence": [ { "id": "R-GGA-428961", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-428961" } ] }, { "id": "R-GGA-432148", "name": "Fgr may phosphorylate p38 MAPK", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A1D5PIQ5-1", "Q02977-1" ], "evidence": [ { "id": "R-GGA-432148", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-432148" } ] }, { "id": "R-GGA-448955", "name": "Phosphorylation of MEF2 proteins by p38", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0X2Y2-1", "A0A1D5PIQ5-1" ], "evidence": [ { "id": "R-GGA-448955", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-448955" } ] }, { "id": "R-GGA-448958", "name": "Nuclear translocation of p38 MAPK", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V1ACF7-1", "A0A8V0X2Y2-1", "A0A1D5PIQ5-1", "Q90694-1" ], "evidence": [ { "id": "R-GGA-448958", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-448958" } ] }, { "id": "R-GGA-450222", "name": "Active p38 MAPK phosphorylates MAPKAPK2 or 3", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1NCY7-1", "A0A1D5PIQ5-1" ], "evidence": [ { "id": "R-GGA-450222", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-450222" } ] }, { "id": "R-GGA-450257", "name": "Nuclear export of human p38 MAPK mediated by its substrate MAPKAPK2 or 3", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1NCY7-1", "A0A1D5PIQ5-1" ], "evidence": [ { "id": "R-GGA-450257", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-450257" } ] }, { "id": "R-GGA-450333", "name": "Activated human MKK3/MKK6 phosphorylates p38 MAPK complexed with MAPKAPK2 or MAPKAPK3", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1NVF2-1", "A0A1D5PD64-1", "F1NCY7-1", "A0A1D5PIQ5-1" ], "evidence": [ { "id": "R-GGA-450333", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-450333" } ] }, { "id": "R-GGA-5218804", "name": "p38 MAPK activation by VEGFR", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V1ACB5-1", "E1BS97-1", "A0A8V0X2Y2-1", "A0A1D5PIQ5-1", "A0A3Q2U639-1", "F1NW21-1", "Q90694-1" ], "evidence": [ { "id": "R-GGA-5218804", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5218804" } ] }, { "id": "R-GGA-6798748", "name": "Exocytosis of secretory granule lumen proteins", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "extracellular region, secretory granule lumen", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A1D5PAA8-1", "A0A8V0X7U8-1", "A0A1D5PLH7-1", "A0A8V0XGV3-1", "A0A8V0XQ57-1", "A0A8V1AAF2-1", "A0A8V1ADZ5-1", "A0A8V1AIR0-1", "O57535-1", "Q90835-1", "A0A8V0ZIP8-1", "A0A8V0ZPK4-1", "A0A8V0ZQ64-1", "A0A8V0ZR27-1", "A0A8V0ZWJ4-1", "A0A8V0YHC8-1", "A0A8V0ZFP5-1", "A0A8V0ZG96-1", "A0A8V0ZTG8-1", "A0A8V0ZVL2-1", "A0A8V0Z0N7-1", "A0A8V0Z3A2-1", "F1NG97-1", "A0A8V0ZAK2-1", "A0A8V0ZG12-1", "A0A1D5PIQ5-1", "Q02977-1", "A0A8V0XXA9-1", "A0A8V0YAA4-1", "A0A8V0Y5M6-1", "A0A8V0YBU4-1", "A0A8V0YHT7-1" ], "evidence": [ { "id": "R-GGA-6798748", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798748" } ] }, { "id": "R-GGA-6800434", "name": "Exocytosis of ficolin-rich granule lumen proteins", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "extracellular region, ficolin-1-rich granule lumen", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A1D5PAA8-1", "A0A8V0X7U8-1", "A0A1D5PLH7-1", "A0A8V0XGV3-1", "A0A8V1AAF2-1", "A0A8V1ADZ5-1", "A0A8V1AIR0-1", "F1NI04-1", "A0A1D5PSE5-1", "A0A8V0XAS9-1", "O57535-1", "P08267-1", "Q90835-1", "A0A1L1RSD2-1", "R4GH41-1", "A0A8V0Y6Q3-1", "A0A8V1AMW1-1", "A0A8V0ZPK4-1", "A0A8V0ZQ64-1", "A0A8V0ZR27-1", "A0A8V0ZWJ4-1", "F1NN63-1", "A0A8V1A3K8-1", "A0A8V1A4Q4-1", "A0A8V0YHC8-1", "A0A8V0YXL9-1", "A0A8V0ZFP5-1", "A0A8V0ZG96-1", "A0A8V0ZTG8-1", "A0A8V0ZVL2-1", "A0A8V0Z0N7-1", "A0A8V0Z0Z6-1", "A0A8V0Z3A2-1", "F1NG97-1", "A0A8V0ZAK2-1", "A0A8V0ZG12-1", "A0A1D5PIQ5-1", "Q05744-1", "A0A8V0XX04-1", "A0A8V0XXA9-1", "A0A8V0YAA4-1", "A0A8V0Y4H1-1", "A0A8V0Y5M6-1", "A0A8V0YDR9-1", "A0A8V0YHT7-1" ], "evidence": [ { "id": "R-GGA-6800434", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6800434" } ] }, { "id": "R-GGA-9626880", "name": "MAPK11 or MAPK14 phosphorylates NCF1 at Ser345", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A1D5PIQ5-1" ], "evidence": [ { "id": "R-GGA-9626880", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9626880" } ] }, { "id": "R-GGA-9855910", "name": "USF1 is phosphorylated by p-MAPK14", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A1D5PIQ5-1" ], "evidence": [ { "id": "R-GGA-9855910", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9855910" } ] }, { "id": "R-GGA-9942578", "name": "Phosphorylation of CDC25A by p38 MAPK", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [ "R-GGA-9942581" ], "enzyme_list": [ "A0A8V1A896-1", "A0A1D5PIQ5-1" ], "evidence": [ { "id": "R-GGA-9942578", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9942578" } ] } ], "reaction_participants": [ { "participant_id": "R-GGA-187743", "participant_name": "MAPKAPK2 [cytosol]", "crossref": [ { "id": "F1NCY7", "database": "UniProt", "url": "" }, { "id": "ENSGALG00010027136", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALP00010040050", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALT00010065784", "database": "ENSEMBL", "url": "" }, { "id": "XP_015154548.1", "database": "RefSeq", "url": "" }, { "id": "XP_040547643.1", "database": "RefSeq", "url": "" } ] }, { "participant_id": "R-GGA-187760", "participant_name": "phospho-MAPKAPK2 [cytosol]", "crossref": [ { "id": "ENSGALG00010027136", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALT00010065784", "database": "ENSEMBL", "url": "" }, { "id": "XP_040547643.1", "database": "RefSeq", "url": "" }, { "id": "ENSGALP00010040050", "database": "ENSEMBL", "url": "" }, { "id": "F1NCY7", "database": "UniProt", "url": "" }, { "id": "XP_015154548.1", "database": "RefSeq", "url": "" } ] }, { "participant_id": "R-GGA-198657", "participant_name": "RPS6KA5 [nucleoplasm]", "crossref": [ { "id": "Q5F3L1", "database": "UniProt", "url": "" }, { "id": "ENSGALG00010017703", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALP00010025288", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALT00010042798", "database": "ENSEMBL", "url": "" }, { "id": "Q5F3L1", "database": "PRO", "url": "" }, { "id": "NP_001012605.1", "database": "RefSeq", "url": "" } ] }, { "participant_id": "R-GGA-198683", "participant_name": "phospho-p-S212,S360,S376,T581-RPS6KA5 [nucleoplasm]", "crossref": [ { "id": "ENSGALP00010025288", "database": "ENSEMBL", "url": "" }, { "id": "Q5F3L1", "database": "PRO", "url": "" }, { "id": "Q5F3L1", "database": "UniProt", "url": "" }, { "id": "NP_001012605.1", "database": "RefSeq", "url": "" }, { "id": "ENSGALT00010042798", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALG00010017703", "database": "ENSEMBL", "url": "" } ] }, { "participant_id": "R-GGA-378502", "participant_name": "PLA2G4A [cytosol]", "crossref": [ { "id": "P49147", "database": "UniProt", "url": "" }, { "id": "XP_046778378.1", "database": "RefSeq", "url": "" }, { "id": "XP_040560444.1", "database": "RefSeq", "url": "" }, { "id": "XP_046800268.1", "database": "RefSeq", "url": "" }, { "id": "XP_046800261.1", "database": "RefSeq", "url": "" }, { "id": "XP_040560448.1", "database": "RefSeq", "url": "" }, { "id": "XP_046800271.1", "database": "RefSeq", "url": "" }, { "id": "XP_046778377.1", "database": "RefSeq", "url": "" }, { "id": "XP_046778374.1", "database": "RefSeq", "url": "" }, { "id": "XP_025008534.1", "database": "RefSeq", "url": "" }, { "id": "XP_046800267.1", "database": "RefSeq", "url": "" }, { "id": "XP_046778359.1", "database": "RefSeq", "url": "" }, { "id": "XP_046778369.1", "database": "RefSeq", "url": "" }, { "id": "XP_025008535.1", "database": "RefSeq", "url": "" }, { "id": "XP_046778360.1", "database": "RefSeq", "url": "" }, { "id": "XP_046778371.1", "database": "RefSeq", "url": "" }, { "id": "XP_046778368.1", "database": "RefSeq", "url": "" }, { "id": "XP_046800273.1", "database": "RefSeq", "url": "" }, { "id": "XP_046800263.1", "database": "RefSeq", "url": "" }, { "id": "XP_046778361.1", "database": "RefSeq", "url": "" }, { "id": "NP_990754.1", "database": "RefSeq", "url": "" }, { "id": "XP_046778362.1", "database": "RefSeq", "url": "" }, { "id": "XP_040560446.1", "database": "RefSeq", "url": "" }, { "id": "XP_040560445.1", "database": "RefSeq", "url": "" }, { "id": "XP_015146058.1", "database": "RefSeq", "url": "" }, { "id": "XP_046778370.1", "database": "RefSeq", "url": "" }, { "id": "XP_046778358.1", "database": "RefSeq", "url": "" }, { "id": "XP_046800272.1", "database": "RefSeq", "url": "" }, { "id": "XP_040560447.1", "database": "RefSeq", "url": "" }, { "id": "XP_046800264.1", "database": "RefSeq", "url": "" }, { "id": "P49147", "database": "PRO", "url": "" }, { "id": "6IEJ", "database": "PDB", "url": "" }, { "id": "3.1.1.5", "database": "IntEnz", "url": "" }, { "id": "3.1.1.4", "database": "IntEnz", "url": "" }, { "id": "ENSGALT00010050885", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALP00010030076", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALG00010021027", "database": "ENSEMBL", "url": "" }, { "id": "XP_046778363.1", "database": "RefSeq", "url": "" }, { "id": "XP_046778376.1", "database": "RefSeq", "url": "" }, { "id": "XP_046778367.1", "database": "RefSeq", "url": "" }, { "id": "XP_046778379.1", "database": "RefSeq", "url": "" }, { "id": "XP_046778366.1", "database": "RefSeq", "url": "" }, { "id": "XP_046778365.1", "database": "RefSeq", "url": "" }, { "id": "XP_046778373.1", "database": "RefSeq", "url": "" }, { "id": "XP_046800270.1", "database": "RefSeq", "url": "" }, { "id": "XP_046800269.1", "database": "RefSeq", "url": "" }, { "id": "XP_046778375.1", "database": "RefSeq", "url": "" }, { "id": "XP_046800265.1", "database": "RefSeq", "url": "" }, { "id": "XP_046800262.1", "database": "RefSeq", "url": "" }, { "id": "XP_046778372.1", "database": "RefSeq", "url": "" }, { "id": "XP_046800266.1", "database": "RefSeq", "url": "" } ] }, { "participant_id": "R-GGA-428933", "participant_name": "MAPK14 [cytosol]", "crossref": [ { "id": "A0A1D5PIQ5", "database": "UniProt", "url": "" }, { "id": "ENSGALG00010027041", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALP00010039854", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALT00010065554", "database": "ENSEMBL", "url": "" } ] }, { "participant_id": "R-GGA-428935", "participant_name": "phospho-MAPK14 [cytosol]", "crossref": [ { "id": "ENSGALG00010027041", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALT00010065554", "database": "ENSEMBL", "url": "" }, { "id": "A0A1D5PIQ5", "database": "UniProt", "url": "" }, { "id": "ENSGALP00010039854", "database": "ENSEMBL", "url": "" } ] }, { "participant_id": "R-GGA-450243", "participant_name": "phospho-ATF2 [nucleoplasm]", "crossref": [ { "id": "ENSGALP00010033061", "database": "ENSEMBL", "url": "" }, { "id": "A0A8V0ZR30", "database": "UniProt", "url": "" }, { "id": "ENSGALG00010022485", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALT00010054714", "database": "ENSEMBL", "url": "" } ] }, { "participant_id": "R-GGA-450336", "participant_name": "ATF2 [nucleoplasm]", "crossref": [ { "id": "A0A8V0ZR30", "database": "UniProt", "url": "" }, { "id": "ENSGALG00010022485", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALP00010033061", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALT00010054714", "database": "ENSEMBL", "url": "" } ] }, { "participant_id": "R-GGA-9942581", "participant_name": "phospho-CDC25A [nucleoplasm]", "crossref": [ { "id": "ENSGALP00010040380", "database": "ENSEMBL", "url": "" }, { "id": "A0A8V1A896", "database": "UniProt", "url": "" }, { "id": "ENSGALG00010027269", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALT00010066114", "database": "ENSEMBL", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5PAA8", "gene_name": "GYG1", "activity": [ { "ec_number": "2.4.1.186", "activity": "[1,4-alpha-D-glucosyl](n)-L-tyrosyl-[glycogenin] + UDP-alpha-D-glucose = [1,4-alpha-D-glucosyl](n+1)-L-tyrosyl-[glycogenin] + UDP + H(+).", "evidence": [ { "id": "A0A1D5PAA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PAA8" } ] }, { "ec_number": "2.4.1.186", "activity": "", "evidence": [ { "id": "A0A1D5PAA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PAA8" } ] } ] }, { "uniprot_ac": "A0A1D5PD64", "gene_name": "MAP2K3", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PD64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PD64" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A1D5PD64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PD64" } ] } ] }, { "uniprot_ac": "A0A1D5PIQ5", "gene_name": "MAPK14", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PIQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PIQ5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A1D5PIQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PIQ5" } ] } ] }, { "uniprot_ac": "A0A1D5PLH7", "gene_name": "PRDX4", "activity": [ { "ec_number": "1.11.1.24", "activity": "a hydroperoxide + [thioredoxin]-dithiol = an alcohol + [thioredoxin]-disulfide + H2O.", "evidence": [ { "id": "A0A1D5PLH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLH7" } ] }, { "ec_number": "1.11.1.24", "activity": "", "evidence": [ { "id": "A0A1D5PLH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLH7" } ] } ] }, { "uniprot_ac": "A0A1D5PSE5", "gene_name": "ACLY", "activity": [ { "ec_number": "2.3.3.8", "activity": "oxaloacetate + acetyl-CoA + ADP + phosphate = citrate + ATP + CoA.", "evidence": [ { "id": "A0A1D5PSE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PSE5" } ] }, { "ec_number": "2.3.3.8", "activity": "", "evidence": [ { "id": "A0A1D5PSE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PSE5" } ] } ] }, { "uniprot_ac": "A0A1L1RSD2", "gene_name": "GUSB", "activity": [ { "ec_number": "3.2.1.31", "activity": "a beta-D-glucuronoside + H2O = D-glucuronate + an alcohol.", "evidence": [ { "id": "A0A1L1RSD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RSD2" } ] }, { "ec_number": "3.2.1.31", "activity": "", "evidence": [ { "id": "A0A1L1RSD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RSD2" } ] } ] }, { "uniprot_ac": "A0A3Q2TY19", "gene_name": "MAPK8", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2TY19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TY19" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A3Q2TY19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TY19" } ] } ] }, { "uniprot_ac": "A0A3Q2U639", "gene_name": "FYN", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2U639", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U639" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A3Q2U639", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U639" } ] } ] }, { "uniprot_ac": "A0A8V0X2Y2", "gene_name": "MAPK12", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X2Y2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X2Y2" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0X2Y2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X2Y2" } ] } ] }, { "uniprot_ac": "A0A8V0X7U8", "gene_name": "ALDOA", "activity": [ { "ec_number": "4.1.2.13", "activity": "beta-D-fructose 1,6-bisphosphate = D-glyceraldehyde 3-phosphate + dihydroxyacetone phosphate.", "evidence": [ { "id": "A0A8V0X7U8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X7U8" } ] }, { "ec_number": "4.1.2.13", "activity": "", "evidence": [ { "id": "A0A8V0X7U8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X7U8" } ] } ] }, { "uniprot_ac": "A0A8V0XAS9", "gene_name": "CAPN1", "activity": [ { "ec_number": "3.4.22.52", "activity": "Broad endopeptidase specificity.", "evidence": [ { "id": "A0A8V0XAS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XAS9" } ] }, { "ec_number": "3.4.22.52", "activity": "", "evidence": [ { "id": "A0A8V0XAS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XAS9" } ] } ] }, { "uniprot_ac": "A0A8V0XGV3", "gene_name": "DDX3X", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XGV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XGV3" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0XGV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XGV3" } ] } ] }, { "uniprot_ac": "A0A8V0XLV6", "gene_name": "MAPK10", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XLV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLV6" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0XLV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLV6" } ] } ] }, { "uniprot_ac": "A0A8V0XQ57", "gene_name": "APRT", "activity": [ { "ec_number": "2.4.2.7", "activity": "AMP + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + adenine.", "evidence": [ { "id": "A0A8V0XQ57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ57" } ] }, { "ec_number": "2.4.2.7", "activity": "", "evidence": [ { "id": "A0A8V0XQ57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ57" } ] } ] }, { "uniprot_ac": "A0A8V0XX04", "gene_name": "QPCT", "activity": [ { "ec_number": "2.3.2.5", "activity": "N-terminal L-glutaminyl-[peptide] = N-terminal 5-oxo-L-prolyl-[peptide] + NH4(+).", "evidence": [ { "id": "A0A8V0XX04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XX04" } ] }, { "ec_number": "2.3.2.5", "activity": "", "evidence": [ { "id": "A0A8V0XX04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XX04" } ] } ] }, { "uniprot_ac": "A0A8V0XXA9", "gene_name": "GPI", "activity": [ { "ec_number": "5.3.1.9", "activity": "alpha-D-fructose 6-phosphate = beta-D-fructose 6-phosphate.", "evidence": [ { "id": "A0A8V0XXA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXA9" } ] }, { "ec_number": "5.3.1.9", "activity": "", "evidence": [ { "id": "A0A8V0XXA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXA9" } ] } ] }, { "uniprot_ac": "A0A8V0Y4H1", "gene_name": "CTSB", "activity": [ { "ec_number": "3.4.22.1", "activity": "Hydrolysis of proteins with broad specificity for peptide bonds. Preferentially cleaves -Arg-Arg-|-Xaa bonds in small molecule substrates (thus differing from cathepsin L). In addition to being an endopeptidase, shows peptidyl-dipeptidase activity, liberating C-terminal dipeptides.", "evidence": [ { "id": "A0A8V0Y4H1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y4H1" } ] }, { "ec_number": "3.4.22.1", "activity": "", "evidence": [ { "id": "A0A8V0Y4H1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y4H1" } ] } ] }, { "uniprot_ac": "A0A8V0Y5M6", "gene_name": "HK3", "activity": [ { "ec_number": "2.7.1.1", "activity": "D-fructose + ATP = D-fructose 6-phosphate + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y5M6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5M6" } ] }, { "ec_number": "2.7.1.1", "activity": "", "evidence": [ { "id": "A0A8V0Y5M6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5M6" } ] } ] }, { "uniprot_ac": "A0A8V0Y6Q3", "gene_name": "LTA4H", "activity": [ { "ec_number": "3.3.2.6", "activity": "leukotriene A4 + H2O = leukotriene B4.", "evidence": [ { "id": "A0A8V0Y6Q3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6Q3" } ] }, { "ec_number": "3.3.2.6", "activity": "", "evidence": [ { "id": "A0A8V0Y6Q3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6Q3" } ] } ] }, { "uniprot_ac": "A0A8V0YAA4", "gene_name": "XRCC6", "activity": [ { "ec_number": "4.2.99.18", "activity": "2'-deoxyribonucleotide-(2'-deoxyribose 5'-phosphate)-2'-deoxyribonucleotide-DNA = a 3'-end 2'-deoxyribonucleotide-(2,3-dehydro-2,3-deoxyribose 5'-phosphate)-DNA + a 5'-end 5'-phospho-2'-deoxyribonucleoside-DNA + H(+).", "evidence": [ { "id": "A0A8V0YAA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAA4" } ] }, { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YAA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAA4" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A8V0YAA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAA4" } ] }, { "ec_number": "4.2.99.18", "activity": "", "evidence": [ { "id": "A0A8V0YAA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAA4" } ] } ] }, { "uniprot_ac": "A0A8V0YBU4", "gene_name": "PDXK", "activity": [ { "ec_number": "2.7.1.35", "activity": "pyridoxine + ATP = pyridoxine 5'-phosphate + ADP + H(+).", "evidence": [ { "id": "A0A8V0YBU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBU4" } ] }, { "ec_number": "2.7.1.35", "activity": "", "evidence": [ { "id": "A0A8V0YBU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBU4" } ] } ] }, { "uniprot_ac": "A0A8V0YDR9", "gene_name": "KCMF1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YDR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDR9" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YDR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDR9" } ] } ] }, { "uniprot_ac": "A0A8V0YHC8", "gene_name": "VCP", "activity": [ { "ec_number": "3.6.4.6", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YHC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHC8" } ] }, { "ec_number": "3.6.4.6", "activity": "", "evidence": [ { "id": "A0A8V0YHC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHC8" } ] } ] }, { "uniprot_ac": "A0A8V0YHT7", "gene_name": "DERA", "activity": [ { "ec_number": "4.1.2.4", "activity": "2-deoxy-D-ribose 5-phosphate = D-glyceraldehyde 3-phosphate + acetaldehyde.", "evidence": [ { "id": "A0A8V0YHT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHT7" } ] }, { "ec_number": "4.1.2.4", "activity": "", "evidence": [ { "id": "A0A8V0YHT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHT7" } ] } ] }, { "uniprot_ac": "A0A8V0YXL9", "gene_name": "MMP9", "activity": [ { "ec_number": "3.4.24.35", "activity": "Cleavage of gelatin types I and V and collagen types IV and V.", "evidence": [ { "id": "A0A8V0YXL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXL9" } ] }, { "ec_number": "3.4.24.35", "activity": "", "evidence": [ { "id": "A0A8V0YXL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXL9" } ] } ] }, { "uniprot_ac": "A0A8V0Z0N7", "gene_name": "PPIA", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "A0A8V0Z0N7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0N7" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "A0A8V0Z0N7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0N7" } ] } ] }, { "uniprot_ac": "A0A8V0Z0Z6", "gene_name": "GLB1", "activity": [ { "ec_number": "3.2.1.23", "activity": "Hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides.", "evidence": [ { "id": "A0A8V0Z0Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0Z6" } ] }, { "ec_number": "3.2.1.23", "activity": "", "evidence": [ { "id": "A0A8V0Z0Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0Z6" } ] } ] }, { "uniprot_ac": "A0A8V0Z3A2", "gene_name": "PPIE", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "A0A8V0Z3A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3A2" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "A0A8V0Z3A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3A2" } ] } ] }, { "uniprot_ac": "A0A8V0ZAK2", "gene_name": "PYGL", "activity": [ { "ec_number": "2.4.1.1", "activity": "[(1->4)-alpha-D-glucosyl](n) + phosphate = [(1->4)-alpha-D-glucosyl](n-1) + alpha-D-glucose 1-phosphate.", "evidence": [ { "id": "A0A8V0ZAK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAK2" } ] }, { "ec_number": "2.4.1.1", "activity": "", "evidence": [ { "id": "A0A8V0ZAK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAK2" } ] } ] }, { "uniprot_ac": "A0A8V0ZFP5", "gene_name": "PGAM1", "activity": [ { "ec_number": "5.4.2.11", "activity": "(2R)-2-phosphoglycerate = (2R)-3-phosphoglycerate.", "evidence": [ { "id": "A0A8V0ZFP5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFP5" } ] }, { "ec_number": "5.4.2.4", "activity": "(2R)-3-phospho-glyceroyl phosphate = (2R)-2,3-bisphosphoglycerate + H(+).", "evidence": [ { "id": "A0A8V0ZFP5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFP5" } ] }, { "ec_number": "5.4.2.4", "activity": "", "evidence": [ { "id": "A0A8V0ZFP5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFP5" } ] }, { "ec_number": "5.4.2.11", "activity": "", "evidence": [ { "id": "A0A8V0ZFP5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFP5" } ] } ] }, { "uniprot_ac": "A0A8V0ZG12", "gene_name": "CDA", "activity": [ { "ec_number": "3.5.4.5", "activity": "cytidine + H2O + H(+) = uridine + NH4(+).", "evidence": [ { "id": "A0A8V0ZG12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG12" } ] }, { "ec_number": "3.5.4.5", "activity": "", "evidence": [ { "id": "A0A8V0ZG12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG12" } ] } ] }, { "uniprot_ac": "A0A8V0ZG96", "gene_name": "PKLR", "activity": [ { "ec_number": "2.7.1.40", "activity": "ITP + pyruvate = IDP + phosphoenolpyruvate + H(+).", "evidence": [ { "id": "A0A8V0ZG96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG96" } ] }, { "ec_number": "2.7.1.40", "activity": "", "evidence": [ { "id": "A0A8V0ZG96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG96" } ] } ] }, { "uniprot_ac": "A0A8V0ZIP8", "gene_name": "XRCC5", "activity": [ { "ec_number": "4.2.99.18", "activity": "2'-deoxyribonucleotide-(2'-deoxyribose 5'-phosphate)-2'-deoxyribonucleotide-DNA = a 3'-end 2'-deoxyribonucleotide-(2,3-dehydro-2,3-deoxyribose 5'-phosphate)-DNA + a 5'-end 5'-phospho-2'-deoxyribonucleoside-DNA + H(+).", "evidence": [ { "id": "A0A8V0ZIP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIP8" } ] }, { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZIP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIP8" } ] }, { "ec_number": "4.2.99.18", "activity": "", "evidence": [ { "id": "A0A8V0ZIP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIP8" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A8V0ZIP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIP8" } ] } ] }, { "uniprot_ac": "A0A8V0ZPK4", "gene_name": "IDH1", "activity": [ { "ec_number": "1.1.1.42", "activity": "D-threo-isocitrate + NADP(+) = 2-oxoglutarate + CO2 + NADPH.", "evidence": [ { "id": "A0A8V0ZPK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPK4" } ] }, { "ec_number": "1.1.1.42", "activity": "", "evidence": [ { "id": "A0A8V0ZPK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPK4" } ] } ] }, { "uniprot_ac": "A0A8V0ZQ64", "gene_name": "AGL", "activity": [ { "ec_number": "2.4.1.25", "activity": "Transfers a segment of a (1->4)-alpha-D-glucan to a new position in an acceptor, which may be glucose or a (1->4)-alpha-D-glucan.", "evidence": [ { "id": "A0A8V0ZQ64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ64" } ] }, { "ec_number": "3.2.1.33", "activity": "Hydrolysis of (1->6)-alpha-D-glucosidic branch linkages in glycogen phosphorylase limit dextrin.", "evidence": [ { "id": "A0A8V0ZQ64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ64" } ] }, { "ec_number": "2.4.1.25", "activity": "", "evidence": [ { "id": "A0A8V0ZQ64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ64" } ] }, { "ec_number": "3.2.1.33", "activity": "", "evidence": [ { "id": "A0A8V0ZQ64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ64" } ] } ] }, { "uniprot_ac": "A0A8V0ZR27", "gene_name": "PAFAH1B2", "activity": [ { "ec_number": "3.1.1.47", "activity": "a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + acetate + H(+).", "evidence": [ { "id": "A0A8V0ZR27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR27" } ] }, { "ec_number": "3.1.1.47", "activity": "", "evidence": [ { "id": "A0A8V0ZR27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR27" } ] } ] }, { "uniprot_ac": "A0A8V0ZTG8", "gene_name": "PFKL", "activity": [ { "ec_number": "2.7.1.11", "activity": "beta-D-fructose 6-phosphate + ATP = beta-D-fructose 1,6-bisphosphate + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZTG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTG8" } ] }, { "ec_number": "2.7.1.11", "activity": "", "evidence": [ { "id": "A0A8V0ZTG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTG8" } ] } ] }, { "uniprot_ac": "A0A8V0ZVL2", "gene_name": "CAT", "activity": [ { "ec_number": "1.11.1.6", "activity": "2 H2O2 = O2 + 2 H2O.", "evidence": [ { "id": "A0A8V0ZVL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVL2" } ] }, { "ec_number": "1.11.1.6", "activity": "", "evidence": [ { "id": "A0A8V0ZVL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVL2" } ] } ] }, { "uniprot_ac": "A0A8V0ZWJ4", "gene_name": "ALOX5", "activity": [ { "ec_number": "1.13.11.34", "activity": "(5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 = leukotriene A4 + H2O.", "evidence": [ { "id": "A0A8V0ZWJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWJ4" } ] }, { "ec_number": "1.13.11.34", "activity": "", "evidence": [ { "id": "A0A8V0ZWJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWJ4" } ] } ] }, { "uniprot_ac": "A0A8V1A3K8", "gene_name": "APEH", "activity": [ { "ec_number": "3.4.19.1", "activity": "Internal cleavage of oxidized and glycated proteins.", "evidence": [ { "id": "A0A8V1A3K8", "database": "UniProtKB", "url": 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"https://www.ncbi.nlm.nih.gov/protein/XP_015145415" } ] } ], "protein_names": [ { "name": "Peroxisome proliferator-activated receptor alpha", "type": "recommended", "evidence": [ { "id": "A0A1D5PJQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJQ2/entry#names_and_taxonomy" } ] }, { "name": "Nuclear receptor subfamily 1 group C member 1", "type": "synonym", "evidence": [ { "id": "A0A1D5PJQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJQ2/entry#names_and_taxonomy" } ] }, { "name": "peroxisome proliferator-activated receptor alpha isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015145415", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015145415" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015145415", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015145415" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PJQ2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJQ2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PPARA", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJQ2", "locus": { "chromosome": "1", "start_pos": 71353475, "end_pos": 71319312, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010023058", "url": "https://www.ensembl.org/id/ENSGALG00010023058" } ] } } ], "crossref": [ { "id": "A0A1D5PJQ2", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PJQ2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000041470", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000041470", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd06932", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06932", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd06965", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06965", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "374120", "url": "https://www.ncbi.nlm.nih.gov/gene/374120", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000536", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000536", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001628", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001628", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001723", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001723", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003074", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003074", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003076", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003076", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013088", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013088", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035500", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035500", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050234", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050234", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "TNHPDNI", "url": "https://omabrowser.org/oma/group/TNHPDNI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PJQ2", "url": "https://www.orthodb.org/?gene=A0A1D5PJQ2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24082", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24082", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24082:SF197", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24082:SF197", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00104", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00104", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00105", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00105", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-383280", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-383280", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-400206", "url": 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"MVDTENQLYPLTPLEEDDIGSPLSGEFLQDMENIQDISQSLGDDSSGALSLTEFQSLGNGPGSDGSVITDTLSPASSPSSINFATAPGSIDESPSGALNIECRICGDKASGYHYGVHACEGCKGFFRRTIRLKLIYDKCDRNCKIQKKNRNKCQYCRFQKCLSVGMSHNAIRFGRMPRSEKAKLKAEILTGENYVEDSEMADLKSLAKRIHDAYLKNFNMNKVKARVILAGKTNNNPPFVIHDMDTLCMAEKTLVAKLVANGIQNKEAEVRIFHCCQCTSVETVTELTEFAKSIPGFSNLDLNDQVTLLKYGVYEAIFAMLASVMNKDGMLVAYGNGFITREFLKSLRKPFCDIMEPKFDFAMKFNALELDDSDISLFVAAIICCGDRPGLVNVGHIEKMQESIVHVLKLHLQTNHPDDIFLFPKLLQKMADLRQLVTEHAQLVQIIKKTESDAHLHPLLQEIYRDMY", "length": 468, "header": "tr|A0A1D5PJQ2-1|A0A1D5PJQ2_CHICK Isoform 1 of Peroxisome proliferator-activated receptor alpha OS=Gallus gallus OX=9031 GN=PPARA PE=3 SV=1 CANONICAL=A0A1D5PJQ2-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PJQ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJQ2/entry#A0A1D5PJQ2-1", "sequence": { "sequence": "MVDTENQLYPLTPLEEDDIGSPLSGEFLQDMENIQDISQSLGDDSSGALSLTEFQSLGNGPGSDGSVITDTLSPASSPSSINFATAPGSIDESPSGALNIECRICGDKASGYHYGVHACEGCKGFFRRTIRLKLIYDKCDRNCKIQKKNRNKCQYCRFQKCLSVGMSHNAIRFGRMPRSEKAKLKAEILTGENYVEDSEMADLKSLAKRIHDAYLKNFNMNKVKARVILAGKTNNNPPFVIHDMDTLCMAEKTLVAKLVANGIQNKEAEVRIFHCCQCTSVETVTELTEFAKSIPGFSNLDLNDQVTLLKYGVYEAIFAMLASVMNKDGMLVAYGNGFITREFLKSLRKPFCDIMEPKFDFAMKFNALELDDSDISLFVAAIICCGDRPGLVNVGHIEKMQESIVHVLKLHLQTNHPDDIFLFPKLLQKMADLRQLVTEHAQLVQIIKKTESDAHLHPLLQEIYRDMY", "length": 468, "header": "tr|A0A1D5PJQ2-1|A0A1D5PJQ2_CHICK Isoform 1 of Peroxisome proliferator-activated receptor alpha OS=Gallus gallus OX=9031 GN=PPARA PE=3 SV=1 CANONICAL=A0A1D5PJQ2-1" }, "locus": { "chromosome": "1", "start_pos": 71352939, "end_pos": 71341598, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056140.1", "url": "https://www.ensembl.org/id/ENSGALT00010056140.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033963.1", "url": "https://www.ensembl.org/id/ENSGALP00010033963.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-383280", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-383280", "resource": "Reactome", "description": "Nuclear Receptor transcription pathway" }, { "id": "R-GGA-400206", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-400206", "resource": "Reactome", "description": "Regulation of lipid metabolism by PPARalpha" }, { "id": "R-GGA-4090294", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4090294", "resource": "Reactome", "description": "SUMOylation of intracellular receptors" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3L7IAI3-1", "protein_name": "Peroxisome proliferator-activated receptor alpha", "gene_name": "Ppara", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MVDTESPICPLSPLEADDLESPLSEEFLQEMGNIQEISQSLEEESSGSFSFTDYQYLGSCPGSEGSVITDTLSPASSPSSVSCPVIPVSTDESPGSALNIECRICGDKASGYHYGVHACEGCKGFFRRTIRLKLVYDKCDRSCKIQKKNRNKCQYCRFHKCLSVGMSHNAIRFGRMPRSEKAKLKAEILTCEHDLEDSETADLKSLAKRIHEAYLKNFNMNKVKARVILAGKTSNNPPFVIHDMETLCMAEKTLVAKMVANGIQNKEAEVRIFHCCQCMSVETVTELTEFAKAIPGFANLDLNDQVTLLKYGVYEAIFTMLSSLMNKDGMLIAYGNGFITREFLKNLRKPFCDILEPKFDFAMKFNALELDDSDISLFVAAIICCGDRPGLLNIGYIEKMQEGIVHVLKLHLQSNHPDDTFLFPKLLQKMVDLRQLVTEHAQLVQVIKKTETDAALHPLLQEIYRDMY", "length": 468 }, "evidence": [ { "id": "A0A1D5PJQ2", "url": "https://omabrowser.org/oma/group/A0A1D5PJQ2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P23204-1", "protein_name": "Peroxisome proliferator-activated receptor alpha", "gene_name": "Ppara", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVDTESPICPLSPLEADDLESPLSEEFLQEMGNIQEISQSIGEESSGSFGFADYQYLGSCPGSEGSVITDTLSPASSPSSVSCPVIPASTDESPGSALNIECRICGDKASGYHYGVHACEGCKGFFRRTIRLKLVYDKCDRSCKIQKKNRNKCQYCRFHKCLSVGMSHNAIRFGRMPRSEKAKLKAEILTCEHDLKDSETADLKSLGKRIHEAYLKNFNMNKVKARVILAGKTSNNPPFVIHDMETLCMAEKTLVAKMVANGVEDKEAEVRFFHCCQCMSVETVTELTEFAKAIPGFANLDLNDQVTLLKYGVYEAIFTMLSSLMNKDGMLIAYGNGFITREFLKNLRKPFCDIMEPKFDFAMKFNALELDDSDISLFVAAIICCGDRPGLLNIGYIEKLQEGIVHVLKLHLQSNHPDDTFLFPKLLQKMVDLRQLVTEHAQLVQVIKKTESDAALHPLLQEIYRDMY", "length": 468 }, "evidence": [ { "id": "A0A1D5PJQ2", "url": "https://omabrowser.org/oma/group/A0A1D5PJQ2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P37230-1", "protein_name": "Peroxisome proliferator-activated receptor alpha", "gene_name": "Ppara", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVDTESPICPLSPLEADDLESPLSEEFLQEMGNIQEISQSLGEESSGSFSFADYQYLGSCPGSEGSVITDTLSPASSPSSVSCPAVPTSTDESPGNALNIECRICGDKASGYHYGVHACEGCKGFFRRTIRLKLAYDKCDRSCKIQKKNRNKCQYCRFHKCLSVGMSHNAIRFGRMPRSEKAKLKAEILTCEHDLKDSETADLKSLAKRIHEAYLKNFNMNKVKARVILAGKTSNNPPFVIHDMETLCMAEKTLVAKMVANGVENKEAEVRFFHCCQCMSVETVTELTEFAKAIPGFANLDLNDQVTLLKYGVYEAIFTMLSSLMNKDGMLIAYGNGFITREFLKNLRKPFCDIMEPKFDFAMKFNALELDDSDISLFVAAIICCGDRPGLLNIGYIEKLQEGIVHVLKLHLQSNHPDDTFLFPKLLQKMVDLRQLVTEHAQLVQVIKKTESDAALHPLLQEIYRDMY", "length": 468 }, "evidence": [ { "id": "A0A1D5PJQ2", "url": "https://omabrowser.org/oma/group/A0A1D5PJQ2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q07869-1", "protein_name": "Peroxisome proliferator-activated receptor alpha", "gene_name": "PPARA", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVDTESPLCPLSPLEAGDLESPLSEEFLQEMGNIQEISQSIGEDSSGSFGFTEYQYLGSCPGSDGSVITDTLSPASSPSSVTYPVVPGSVDESPSGALNIECRICGDKASGYHYGVHACEGCKGFFRRTIRLKLVYDKCDRSCKIQKKNRNKCQYCRFHKCLSVGMSHNAIRFGRMPRSEKAKLKAEILTCEHDIEDSETADLKSLAKRIYEAYLKNFNMNKVKARVILSGKASNNPPFVIHDMETLCMAEKTLVAKLVANGIQNKEAEVRIFHCCQCTSVETVTELTEFAKAIPGFANLDLNDQVTLLKYGVYEAIFAMLSSVMNKDGMLVAYGNGFITREFLKSLRKPFCDIMEPKFDFAMKFNALELDDSDISLFVAAIICCGDRPGLLNVGHIEKMQEGIVHVLRLHLQSNHPDDIFLFPKLLQKMADLRQLVTEHAQLVQIIKKTESDAALHPLLQEIYRDMY", "length": 468 }, "evidence": [ { "id": "A0A1D5PJQ2", "url": "https://omabrowser.org/oma/group/A0A1D5PJQ2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 21, "go_terms": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PJQ2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJQ2" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PJQ2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJQ2" } ], "pmid": "" }, { "name": "fatty acid metabolic process", "id": "GO:0006631", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006631", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PJQ2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJQ2" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PJQ2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJQ2" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PJQ2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJQ2" } ], "pmid": "" }, { "name": "positive regulation of lipid biosynthetic process", "id": "GO:0046889", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046889", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PJQ2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJQ2" } ], "pmid": "" }, { "name": "negative regulation of inflammatory response", "id": "GO:0050728", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050728", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PJQ2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJQ2" } ], "pmid": "" }, { "name": "negative regulation of macrophage derived foam cell differentiation", "id": "GO:0010745", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010745", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PJQ2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJQ2" } ], "pmid": "" }, { "name": "negative regulation of cholesterol storage", "id": "GO:0010887", 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"A0A1D5PJX0-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJX0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PU07", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PU07", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PU07-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PU07-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A4G4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4G4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A4G4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4G4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGR9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGR9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGR9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGR9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C784", "url": "https://www.uniprot.org/uniprotkb/E1C784", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C784-1", "url": "https://www.uniprot.org/uniprotkb/E1C784-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTNNVADHHPGNSVAEGNHEGDFGCSMVELRNLMELRSAEAVARISDSYGGVQTVCKRLKTSPVEGLSGNPTDLEKRRQVFGQNFIPPKKAKTFLQLVWEALQDVTLIILEIAAIISLGLSFYHPPGGDNELCGQSSGGVEDEGEAQAGWIEGAAILFSVIIVVLVTAFNDWSKEKQFRGLQSRIEQEQKFTVIRKGQVIQIPVAEIVVGDIAQIKYGDLLPADGILIQGNDLKIDESSLTGESDQVKKSLDKDPMLLSGTHVMEGSGRMVVTAVGINSQTGIIFTLLGAGEGDEEKKVKKGKKTGAPENRNKAKTQDGVALEIQPLKSQEGVENEEKEKKKVKVPKKEKSVLQGKLTRLAVQIGKAGLIMSAITVIILVLYFVIDTFGVQRRPWLAECTPIYIQYFVKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTMNRMTVVQAYVGDTHYRQIPDPEAILPKVLDLIVNGVAINSAYTSKILPPEKEGGLPRQVGNKTECALLGFVLDLKQDYQAVRNEVPEEKLYKVYTFNSVRKSMSTVLKNSDNSFRMYSKGASEIILRKCTKILDKNGDPRMFKVKDRDEMVKKVIEPMACHGLRTICLAFRDFPADAEPDWDSENEILSDLTCIAVVGIEDPVRPEVPDAILKCQRAGITVRMVTGDNINTARAIATKCGILLPGEDFLCLEGKEFNRLIRNEKGEVEQEQLDKIWPKLRVLARSSPTDKHTLVKGIIDSTVGDQRQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPSESLLLRKPYGRNKPLISRTMMKNILGHAVYQLTIIFTLLFVGEKLFDIDSGRNAPLHSPPTEHYTIVFNTFVMMQLFNEINARKIHGERNVFEAIYRNPIFCTVVLGTFAAQIIIVEFGGKPFSCSGLTLSQWFWCIFIGVGELLWGQLICTVPTSHLKFLKEAGHGITKEEIPEEELPEDVDEIDHAEMELRRGQILWFRGLNRIQTQIKVVNAFRSSLYEGLEKPESRSSIHNFMTHPEFILEEDEPRTPFLDSAEDDPKTDGLKKRGGGSLGGSSSLNRNNNAVDSDQTEVNFAEPESLFHSLETSV", "length": 1208, "header": "tr|A0A1D5PJX0-1|A0A1D5PJX0_CHICK Isoform 1 of Calcium-transporting ATPase OS=Gallus gallus OX=9031 GN=ATP2B4 PE=1 SV=2 CANONICAL=A0A1D5PJX0-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PJX0-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJX0/entry#A0A1D5PJX0-1", "sequence": { "sequence": "MTNNVADHHPGNSVAEGNHEGDFGCSMVELRNLMELRSAEAVARISDSYGGVQTVCKRLKTSPVEGLSGNPTDLEKRRQVFGQNFIPPKKAKTFLQLVWEALQDVTLIILEIAAIISLGLSFYHPPGGDNELCGQSSGGVEDEGEAQAGWIEGAAILFSVIIVVLVTAFNDWSKEKQFRGLQSRIEQEQKFTVIRKGQVIQIPVAEIVVGDIAQIKYGDLLPADGILIQGNDLKIDESSLTGESDQVKKSLDKDPMLLSGTHVMEGSGRMVVTAVGINSQTGIIFTLLGAGEGDEEKKVKKGKKTGAPENRNKAKTQDGVALEIQPLKSQEGVENEEKEKKKVKVPKKEKSVLQGKLTRLAVQIGKAGLIMSAITVIILVLYFVIDTFGVQRRPWLAECTPIYIQYFVKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTMNRMTVVQAYVGDTHYRQIPDPEAILPKVLDLIVNGVAINSAYTSKILPPEKEGGLPRQVGNKTECALLGFVLDLKQDYQAVRNEVPEEKLYKVYTFNSVRKSMSTVLKNSDNSFRMYSKGASEIILRKCTKILDKNGDPRMFKVKDRDEMVKKVIEPMACHGLRTICLAFRDFPADAEPDWDSENEILSDLTCIAVVGIEDPVRPEVPDAILKCQRAGITVRMVTGDNINTARAIATKCGILLPGEDFLCLEGKEFNRLIRNEKGEVEQEQLDKIWPKLRVLARSSPTDKHTLVKGIIDSTVGDQRQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPSESLLLRKPYGRNKPLISRTMMKNILGHAVYQLTIIFTLLFVGEKLFDIDSGRNAPLHSPPTEHYTIVFNTFVMMQLFNEINARKIHGERNVFEAIYRNPIFCTVVLGTFAAQIIIVEFGGKPFSCSGLTLSQWFWCIFIGVGELLWGQLICTVPTSHLKFLKEAGHGITKEEIPEEELPEDVDEIDHAEMELRRGQILWFRGLNRIQTQIKVVNAFRSSLYEGLEKPESRSSIHNFMTHPEFILEEDEPRTPFLDSAEDDPKTDGLKKRGGGSLGGSSSLNRNNNAVDSDQTEVNFAEPESLFHSLETSV", "length": 1208, "header": "tr|A0A1D5PJX0-1|A0A1D5PJX0_CHICK Isoform 1 of Calcium-transporting ATPase OS=Gallus gallus OX=9031 GN=ATP2B4 PE=1 SV=2 CANONICAL=A0A1D5PJX0-1" }, "locus": { "chromosome": "26", "start_pos": 5285469, "end_pos": 5263278, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066603.1", "url": "https://www.ensembl.org/id/ENSGALT00010066603.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040784.1", "url": "https://www.ensembl.org/id/ENSGALP00010040784.1" } ] } }, { "isoform_ac": "A0A1D5PU07-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJX0/entry#A0A1D5PU07-1", "sequence": { "sequence": "MTNNVADHHPGNSVAEGNHEGDFGCSMVELRNLMELRSAEAVARISDSYGGVQTVCKRLKTSPVEGLSGNPTDLEKRRQVFGQNFIPPKKAKTFLQLVWEALQDVTLIILEIAAIISLGLSFYHPPGGDNELCGQSSGGVEDEGEAQAGWIEGAAILFSVIIVVLVTAFNDWSKEKQFRGLQSRIEQEQKFTVIRKGQVIQIPVAEIVVGDIAQIKYGDLLPADGILIQGNDLKIDESSLTGESDQVKKSLDKDPMLLSGTHVMEGSGRMVVTAVGINSQTGIIFTLLGAGEGDEEKKVKKAKTQDGVALEIQPLKSQEGVENEEKEKKKVKVPKKEKSVLQGKLTRLAVQIGKAGLIMSAITVIILVLYFVIDTFGVQRRPWLAECTPIYIQYFVKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTMNRMTVVQAYVGDTHYRQIPDPEAILPKVLDLIVNGVAINSAYTSKILPPEKEGGLPRQVGNKTECALLGFVLDLKQDYQAVRNEVPEEKLYKVYTFNSVRKSMSTVLKNSDNSFRMYSKGASEIILRKCTKILDKNGDPRMFKVKDRDEMVKKVIEPMACHGLRTICLAFRDFPADAEPDWDSENEILSDLTCIAVVGIEDPVRPEVPDAILKCQRAGITVRMVTGDNINTARAIATKCGILLPGEDFLCLEGKEFNRLIRNEKGEVEQEQLDKIWPKLRVLARSSPTDKHTLVKGIIDSTVGDQRQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPSESLLLRKPYGRNKPLISRTMMKNILGHAVYQLTIIFTLLFVGEKLFDIDSGRNAPLHSPPTEHYTIVFNTFVMMQLFNEINARKIHGERNVFEAIYRNPIFCTVVLGTFAAQIIIVEFGGKPFSCSGLTLSQWFWCIFIGVGELLWGQLICTVPTSHLKFLKEAGHGITKEEIPEEELPEDVDEIDHAEMELRRGQILWFRGLNRIQTQMDVVYTFQTGASSLQGALRRQPSIVSQHHDVKNVSSPTHVALSSVNSTPTTSAVAAAASSPAGNQGGECVP", "length": 1166, "header": "tr|A0A1D5PU07-1|A0A1D5PJX0_CHICK Computationally mapped isoform of Calcium-transporting ATPase OS=Gallus gallus OX=9031 GN=ATP2B4 PE=1 SV=2 CANONICAL=A0A1D5PJX0-1" }, "locus": { "chromosome": "26", "start_pos": 5285189, "end_pos": 5263278, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066606.1", "url": "https://www.ensembl.org/id/ENSGALT00010066606.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040785.1", "url": "https://www.ensembl.org/id/ENSGALP00010040785.1" } ] } }, { "isoform_ac": "A0A8V1A4G4-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJX0/entry#A0A8V1A4G4-1", "sequence": { "sequence": "MTNNVADHHPGNSVAEGNHEGDFGCSMVELRNLMELRSAEAVARISDSYGGVQTVCKRLKTSPVEGLSGNPTDLEKRRQVFGQNFIPPKKAKTFLQLVWEALQDVTLIILEIAAIISLGLSFYHPPGGDNELCGQSSGGVEDEGEAQAGWIEGAAILFSVIIVVLVTAFNDWSKEKQFRGLQSRIEQEQKFTVIRKGQVIQIPVAEIVVGDIAQIKYGDLLPADGILIQGNDLKIDESSLTGESDQVKKSLDKDPMLLSGTHVMEGSGRMVVTAVGINSQTGIISTFAPRPV", "length": 292, "header": "tr|A0A8V1A4G4-1|A0A1D5PJX0_CHICK Computationally mapped isoform of Calcium-transporting ATPase OS=Gallus gallus OX=9031 GN=ATP2B4 PE=1 SV=1 CANONICAL=A0A1D5PJX0-1" }, "locus": { "chromosome": "26", "start_pos": 5285550, "end_pos": 5263278, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066608.1", "url": "https://www.ensembl.org/id/ENSGALT00010066608.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040786.1", "url": "https://www.ensembl.org/id/ENSGALP00010040786.1" } ] } }, { "isoform_ac": "A0A8V1AGR9-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJX0/entry#A0A8V1AGR9-1", "sequence": { "sequence": "MTNNVADHHPGNSVAEGNHEGDFGCSMVELRNLMELRSAEAVARISDSYGGVQTVCKRLKTSPVEGLSGNPTDLEKRRQVFGQNFIPPKKAKTFLQLVWEALQDVTLIILEIAAIISLGLSFYHPPGGDNELCGQSSGGVEDEGEAQAGWIEGAAILFSVIIVVLVTAFNDWSKEKQFRGLQSRIEQEQKFTVIRKGQVIQIPVAEIVVGDIAQIKYGDLLPADGILIQGNDLKIDESSLTGESDQVKKSLDKDPMLLSGTHVMEGSGRMVVTAVGINSQTGIIFTLLGAGEGDEEKKVKKGKKTGAPENRNKAKTQDGVALEIQPLKSQEGVENEEKEKKKVKVPKKEKSVLQGKLTRLAVQIGKAGLIMSAITVIILVLYFVIDTFGVQRRPWLAECTPIYIQYFVKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTMNRMTVVQAYVGDTHYRQIPDPEAILPKVLDLIVNGVAINSAYTSKILPPEKEGGLPRQVGNKTECALLGFVLDLKQDYQAVRNEVPEEKLYKVYTFNSVRKSMSTVLKNSDNSFRMYSKGASEIILRKCTKILDKNGDPRMFKVKDRDEMVKKVIEPMACHGLRTICLAFRDFPADAEPDWDSENEILSDLTCIAVVGIEDPVRPEVPDAILKCQRAGITVRMVTGDNINTARAIATKCGILLPGEDFLCLEGKEFNRLIRNEKGEVEQEQLDKIWPKLRVLARSSPTDKHTLVKGIIDSTVGDQRQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPSESLLLRKPYGRNKPLISRTMMKNILGHAVYQLTIIFTLLFVGEKLFDIDSGRNAPLHSPPTEHYTIVFNTFVMMQLFNEINARKIHGERNVFEAIYRNPIFCTVVLGTFAAQIIIVEFGGKPFSCSGLTLSQWFWCIFIGVGELLWGQLICTVPTSHLKFLKEAGHGITKEEIPEEELPEDVDEIDHAEMELRRGQILWFRGLNRIQTQADVSWYQPWAV", "length": 1118, "header": "tr|A0A8V1AGR9-1|A0A1D5PJX0_CHICK Computationally mapped isoform of Calcium-transporting ATPase OS=Gallus gallus OX=9031 GN=ATP2B4 PE=1 SV=1 CANONICAL=A0A1D5PJX0-1" }, "locus": { "chromosome": "26", "start_pos": 5278554, "end_pos": 5263278, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066600.1", "url": "https://www.ensembl.org/id/ENSGALT00010066600.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040782.1", "url": "https://www.ensembl.org/id/ENSGALP00010040782.1" } ] } }, { "isoform_ac": "E1C784-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJX0/entry#E1C784-1", "sequence": { "sequence": "MTNNVADHHPGNSVAEGNHEGDFGCSMVELRNLMELRSAEAVARISDSYGGVQTVCKRLKTSPVEGLSGNPTDLEKRRQVFGQNFIPPKKAKTFLQLVWEALQDVTLIILEIAAIISLGLSFYHPPGGDNELCGQSSGGVEDEGEAQAGWIEGAAILFSVIIVVLVTAFNDWSKEKQFRGLQSRIEQEQKFTVIRKGQVIQIPVAEIVVGDIAQIKYGDLLPADGILIQGNDLKIDESSLTGESDQVKKSLDKDPMLLSGTHVMEGSGRMVVTAVGINSQTGIIFTLLGAGEGDEEKKVKKGKKTGAPENRNKAKTQDGVALEIQPLKSQEGVENEEKEKKKVKVPKKEKSVLQGKLTRLAVQIGKAGLIMSAITVIILVLYFVIDTFGVQRRPWLAECTPIYIQYFVKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTMNRMTVVQAYVGDTHYRQIPDPEAILPKVLDLIVNGVAINSAYTSKILPPEKEGGLPRQVGNKTECALLGFVLDLKQDYQAVRNEVPEEKLYKVYTFNSVRKSMSTVLKNSDNSFRMYSKGASEIILRKCTKILDKNGDPRMFKVKDRDEMVKKVIEPMACHGLRTICLAFRDFPADAEPDWDSENEILSDLTCIAVVGIEDPVRPEVPDAILKCQRAGITVRMVTGDNINTARAIATKCGILLPGEDFLCLEGKEFNRLIRNEKGEVEQEQLDKIWPKLRVLARSSPTDKHTLVKGIIDSTVGDQRQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPSESLLLRKPYGRNKPLISRTMMKNILGHAVYQLTIIFTLLFVGEKLFDIDSGRNAPLHSPPTEHYTIVFNTFVMMQLFNEINARKIHGERNVFEAIYRNPIFCTVVLGTFAAQIIIVEFGGKPFSCSGLTLSQWFWCIFIGVGELLWGQLICTVPTSHLKFLKEAGHGITKEEIPEEELPEDVDEIDHAEMELRRGQILWFRGLNRIQTQIKVVNAFRSSLYEGLEKPESRSSIHNFMTHPEFILEEDEPRTPFLDSAEDDPKTDGLKKRAQH", "length": 1170, "header": "tr|E1C784-1|A0A1D5PJX0_CHICK Computationally mapped isoform of Calcium-transporting ATPase OS=Gallus gallus OX=9031 GN=ATP2B4 PE=1 SV=4 CANONICAL=A0A1D5PJX0-1" }, "locus": { "chromosome": "26", "start_pos": 5287400, "end_pos": 5263278, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066611.1", "url": "https://www.ensembl.org/id/ENSGALT00010066611.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040788.1", "url": "https://www.ensembl.org/id/ENSGALP00010040788.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-GGA-418359", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-418359", "resource": "Reactome", "description": "Reduction of cytosolic Ca++ levels" }, { "id": "R-GGA-5578775", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5578775", "resource": "Reactome", "description": "Ion homeostasis" }, { "id": "R-GGA-936837", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-936837", "resource": "Reactome", "description": "Ion transport by P-type ATPases" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 8, "go_terms": [ { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PJX0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJX0" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PJX0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJX0" } ], "pmid": "" }, { "name": "membrane raft", "id": "GO:0045121", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045121", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PJX0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJX0" } ], "pmid": "" }, { "name": "sperm flagellum", "id": "GO:0036126", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036126", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PJX0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJX0" } ], "pmid": "" }, { "name": "Z disc", "id": "GO:0030018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030018", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PJX0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJX0" } ], "pmid": "" }, { "name": "T-tubule", "id": "GO:0030315", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030315", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PJX0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJX0" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PJX0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJX0" } ], "pmid": "" }, { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PJX0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJX0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 8, "go_terms": [ { "name": "calmodulin binding", "id": "GO:0005516", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005516", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PJX0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJX0" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PJX0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJX0" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PJX0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJX0" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PJX0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJX0" } ], "pmid": "" }, { "name": "nitric-oxide synthase binding", "id": "GO:0050998", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050998", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PJX0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJX0" } ], "pmid": "" }, { "name": "protein phosphatase 2B binding", "id": "GO:0030346", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030346", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PJX0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJX0" } ], "pmid": "" }, { "name": "P-type calcium transporter activity", "id": "GO:0005388", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005388", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PJX0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJX0" } ], "pmid": "" }, { "name": "nitric-oxide synthase inhibitor activity", "id": "GO:0036487", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036487", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PJX0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJX0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 20, "go_terms": [ { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PJX0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJX0" } ], "pmid": "" }, { "name": "negative regulation of gene expression", "id": "GO:0010629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010629", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PJX0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJX0" } ], "pmid": "" }, { "name": "flagellated sperm motility", "id": "GO:0030317", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030317", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PJX0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJX0" } ], "pmid": "" }, { "name": "regulation of cytosolic calcium ion concentration", "id": "GO:0051480", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051480", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PJX0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJX0" } ], "pmid": "" }, { "name": "negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway", "id": "GO:0071878", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071878", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PJX0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJX0" } ], "pmid": "" }, { "name": "negative regulation of blood vessel endothelial cell migration", "id": "GO:0043537", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043537", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PJX0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJX0" } ], "pmid": "" }, { "name": "positive regulation of protein localization to plasma membrane", "id": "GO:1903078", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903078", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PJX0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJX0" } ], "pmid": "" }, { "name": "negative regulation of angiogenesis", "id": "GO:0016525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016525", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PJX0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJX0" } ], "pmid": "" }, { "name": "negative regulation of calcineurin-NFAT signaling cascade", "id": "GO:0070885", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070885", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PJX0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJX0" } ], "pmid": "" }, { "name": "cellular response to epinephrine stimulus", "id": "GO:0071872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071872", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PJX0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJX0" } ], "pmid": "" }, { "name": "negative regulation of nitric oxide biosynthetic process", "id": "GO:0045019", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045019", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PJX0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJX0" } ], "pmid": "" }, { "name": "negative regulation of cellular response to vascular endothelial growth factor stimulus", "id": "GO:1902548", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902548", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PJX0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJX0" } ], "pmid": "" }, { "name": "response to hydrostatic pressure", "id": "GO:0051599", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051599", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PJX0", "url": 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"site_annotation": [ { "start_pos": 459, "end_pos": 461, "annotation": "n_glycosylation_sequon" }, { "start_pos": 534, "end_pos": 536, "annotation": "n_glycosylation_sequon" }, { "start_pos": 824, "end_pos": 826, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "18105", "name": "", "equation": "Ca(2+)(in) + ATP + H2O = Ca(2+)(out) + ADP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q2U0I3-1", "A0A8V0Z7T1-1", "Q98SH2-1", "Q9YGL9-2", "A0A8V0YJL7-1", "A0A1D5PJX0-1", "A0A8V0XTF5-1", "A0A1L1RKB7-1", "P13585-1", "Q03669-1" ], "evidence": [ { "id": "18105", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/18105" } ] }, { "id": "R-GGA-418309", "name": "ATP2B1-4 transport cytosolic Ca2+ to extracellular region", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q2U0I3-1", "Q98SH2-1", "A0A8V0YJL7-1", "A0A1D5PJX0-1" ], "evidence": [ { "id": "R-GGA-418309", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-418309" } ] }, { "id": "R-GGA-5617178", "name": "ATP2B4 binds to NOS1, inhibiting it", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0X354-1", "A0A1D5PJX0-1" ], "evidence": [ { "id": "R-GGA-5617178", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5617178" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5PJX0", "gene_name": "ATP2B4", "activity": [ { "ec_number": "7.2.2.10", "activity": "Ca(2+)(in) + ATP + H2O = Ca(2+)(out) + ADP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5PJX0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJX0" } ] }, { "ec_number": "7.2.2.10", "activity": "", "evidence": [ { "id": "A0A1D5PJX0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJX0" } ] } ] }, { "uniprot_ac": "A0A1L1RKB7", "gene_name": "ATP2A2", "activity": [ { "ec_number": "7.2.2.10", "activity": "Ca(2+)(in) + ATP + H2O = Ca(2+)(out) + ADP + phosphate + H(+).", "evidence": [ { "id": "A0A1L1RKB7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RKB7" } ] }, { "ec_number": "7.2.2.10", "activity": "", "evidence": [ { "id": "A0A1L1RKB7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RKB7" } ] } ] }, { "uniprot_ac": "A0A3Q2U0I3", "gene_name": "ATP2B2", "activity": [ { "ec_number": "7.2.2.10", "activity": "Ca(2+)(in) + ATP + H2O = Ca(2+)(out) + ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q2U0I3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U0I3" } ] }, { "ec_number": "7.2.2.10", "activity": "", "evidence": [ { "id": "A0A3Q2U0I3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U0I3" } ] } ] }, { "uniprot_ac": "A0A8V0X354", "gene_name": "NOS1", "activity": [ { "ec_number": "1.14.13.39", "activity": "2 L-arginine + 3 NADPH + 4 O2 + H(+) = 2 L-citrulline + 2 nitric oxide + 3 NADP(+) + 4 H2O.", "evidence": [ { "id": "A0A8V0X354", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X354" } ] }, { "ec_number": "1.14.13.39", "activity": "", "evidence": [ { "id": "A0A8V0X354", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X354" } ] } ] }, { "uniprot_ac": "A0A8V0XTF5", "gene_name": "ATP2C2", "activity": [ { "ec_number": "7.2.2.10", "activity": "Ca(2+)(in) + ATP + H2O = Ca(2+)(out) + ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XTF5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XTF5" } ] }, { "ec_number": "7.2.2.10", "activity": "", "evidence": [ { "id": "A0A8V0XTF5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XTF5" } ] } ] }, { "uniprot_ac": "A0A8V0YJL7", "gene_name": "ATP2B1", "activity": [ { "ec_number": "7.2.2.10", "activity": "Ca(2+)(in) + ATP + H2O = Ca(2+)(out) + ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YJL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJL7" } ] }, { "ec_number": "7.2.2.10", "activity": "", "evidence": [ { "id": "A0A8V0YJL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJL7" } ] } ] }, { "uniprot_ac": "A0A8V0Z7T1", "gene_name": "ATP2C1", "activity": [ { "ec_number": "7.2.2.10", "activity": "Ca(2+)(in) + ATP + H2O = Ca(2+)(out) + ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0Z7T1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7T1" } ] }, { "ec_number": "7.2.2.10", "activity": "", "evidence": [ { "id": "A0A8V0Z7T1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7T1" } ] } ] }, { "uniprot_ac": "P13585", "gene_name": "ATP2A1", "activity": [ { "ec_number": "7.2.2.10", "activity": "Ca(2+)(in) + ATP + H2O = Ca(2+)(out) + ADP + phosphate + H(+).", "evidence": [ { "id": "P13585", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13585" } ] }, { "ec_number": 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"https://www.uniprot.org/uniprotkb/Q98SH2" } ] } ] }, { "uniprot_ac": "Q9YGL9", "gene_name": "ATP2A3", "activity": [ { "ec_number": "7.2.2.10", "activity": "Ca(2+)(in) + ATP + H2O = Ca(2+)(out) + ADP + phosphate + H(+).", "evidence": [ { "id": "Q9YGL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9YGL9" } ] }, { "ec_number": "7.2.2.10", "activity": "", "evidence": [ { "id": "Q9YGL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9YGL9" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5PJX0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1208, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5PJX0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5PJX0" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A1D5PJX0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJX0" }, { "id": "SM00831", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00831" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Cation-transporting P-type ATPase N-terminal", "eco_id": "ECO_0000259", "start_pos": 48, "end_pos": 122, "start_aa": "Ser", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "7.2.2.10", "ec_name": "Ca(2+)(in) + ATP + H2O = Ca(2+)(out) + ADP + phosphate + H(+).", "evidence": [ { "id": "7.2.2.10", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:7.2.2.10" }, { "id": "7.2.2.10", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=7.2.2.10" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 459, "end_pos": 461 }, { "start_pos": 534, "end_pos": 536 }, { "start_pos": 824, "end_pos": 826 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A1D5PLJ8-1", "uniprot_ac": "A0A1D5PLJ8", "uniprot_id": "A0A1D5PLJ8_CHICK", "mass": { "chemical_mass": 93463.0, "monoisotopic_mass": 93463.0 }, "refseq": { "ac": "NP_001004405", "name": "calpain-3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001004405" }, "gene_names": [ { "name": "CAPN3", "type": "recommended", "evidence": [ { "id": "A0A1D5PLJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLJ8" } ] }, { "name": "CAPN3", "type": "synonym", "evidence": [ { "id": "NP_001004405", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001004405" } ] }, { "name": "p94", "type": "synonym", "evidence": [ { "id": "NP_001004405", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001004405" } ] } ], "protein_names": [ { "name": "Calpain-3", "type": "recommended", "evidence": [ { "id": "A0A1D5PLJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLJ8/entry#names_and_taxonomy" } ] }, { "name": "3.4.22.54", "type": "synonym", "evidence": [ { "id": "A0A1D5PLJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLJ8/entry#names_and_taxonomy" } ] }, { "name": "CANP 3", "type": "synonym", "evidence": [ { "id": "NP_001004405", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001004405" } ] }, { "name": "calcium-activated neutral proteinase 3", "type": "synonym", "evidence": [ { "id": "NP_001004405", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001004405" } ] }, { "name": "calpain L3", "type": "synonym", "evidence": [ { "id": "NP_001004405", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001004405" } ] }, { "name": "calpain p94", "type": "synonym", "evidence": [ { "id": "NP_001004405", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001004405" } ] }, { "name": "calpain-3", "type": "synonym", "evidence": [ { "id": "NP_001004405", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001004405" } ] }, { "name": "muscle-specific calcium-activated neutral protease 3", "type": "synonym", "evidence": [ { "id": "NP_001004405", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001004405" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: D38028.1, FJ497056.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992415, SAMEA103992437 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000214.1. On Mar 13, 2015 this sequence version replaced NP_001004405.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001004405", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001004405" } ] }, { "annotation": "CAPN3 polymorphisms are strongly associated with chicken carcass traits. Publication Status: Online-Only", "evidence": [ { "database": "RefSeq", "id": "NP_001004405", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001004405" }, { "database": "PubMed", "id": "19265533", "url": "https://glygen.org/publication/PubMed/19265533" } ] }, { "annotation": "Calcium-regulated non-lysosomal thiol-protease.", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RQ67", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RQ67#function" }, { "database": "UniProtKB", "id": "RU367132", "url": "https://www.uniprot.org/uniprotkb/RU367132#function" }, { "database": "UniProtKB", "id": "A0A8V0ZBA6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBA6#function" }, { "database": "UniProtKB", "id": "A0A1D5PLJ8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLJ8#function" } ] }, { "annotation": "The present expression data of chicken CAPN3 gene may provide some information to shed light on the tissue and ontogenic expression pattern during chicken development.", "evidence": [ { "database": "RefSeq", "id": "NP_001004405", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001004405" }, { "database": "PubMed", "id": "21713405", "url": "https://glygen.org/publication/PubMed/21713405" } ] }, { "annotation": "The scaffolding protein calpain-3 has multiple distributions in embryonic chick muscle cells and it is essential for the formation of muscle fibers.", "evidence": [ { "database": "RefSeq", "id": "NP_001004405", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001004405" }, { "database": "PubMed", "id": "32932207", "url": "https://glygen.org/publication/PubMed/32932207" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PLJ8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLJ8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CAPN3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLJ8", "locus": { "chromosome": "5", "start_pos": 25194170, "end_pos": 25170021, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010019472", "url": "https://www.ensembl.org/id/ENSGALG00010019472" } ] } } ], "crossref": [ { "id": "A0A1D5PLJ8", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PLJ8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000009050", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000009050", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "3.4.22.54", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.4.22.54&UniProtAcc=A0A1D5PLJ8", "database": "BRENDA", "categories": [ "Enzyme and Pathway" ] }, { "id": "cd00044", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00044", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd00214", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00214", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd16190", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16190", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "423233", "url": "https://www.ncbi.nlm.nih.gov/gene/423233", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000169", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000169", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001300", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001300", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002048", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002048", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018247", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018247", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022682", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022682", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022683", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022683", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022684", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022684", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029531", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029531", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032100", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032100", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033883", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033883", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036213", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036213", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038765", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038765", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR054069", "url": "https://www.ebi.ac.uk/interpro/entry/IPR054069", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:423233", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423233", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QTTHAQN", "url": "https://omabrowser.org/oma/group/QTTHAQN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PLJ8", "url": "https://www.orthodb.org/?gene=A0A1D5PLJ8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A1L1RQ67", "url": "https://www.orthodb.org/?gene=A0A1L1RQ67", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZBA6", "url": "https://www.orthodb.org/?gene=A0A8V0ZBA6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10183", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10183", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10183:SF329", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10183:SF329", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00036", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00036", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00648", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00648", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01067", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01067", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16648", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16648", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21875", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21875", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001004405", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001004405", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PLJ8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLJ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PLJ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLJ8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1L1RQ67", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RQ67", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1L1RQ67-1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RQ67-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZBA6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBA6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZBA6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBA6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPSAINAAVAQQTAAGSVPSTTSTTTEGTGGGTGGIYSAIISRNQPIIKVKEKTYEELHKKCLEENILYEDPDFPPNETSLFYSQKVPIKFEWKRPREICENPRFIIGGANRTDICQGELGDCWFLAAIACLTLNKKLLCRVIPHDQSFIQNYAGIFHFQFWRYGDWVDVIIDDCLPTYNNQLVFTKSSQRNEFWSALLEKAYAKLHGSYEALKGGNTTEAMEDFTGGVTEFYEIKDAPKDIYKIMKHAIARGSLMASSIDDNLGFSYGAAPRSDIGELIARMVKNLENAQMTYSTVDYQGTDERPAWTIMPMQYETRMSCGLVKGHAYSVTAVEETTYKGEKMRLVRLRNPWGQVEWNGPWSDKSEEWNFIDEEEKTRLQHKIAEDGEFWISFEDFMRHFTKLEICNLTPDTLEADKLQTWTVSVNEGRWVRGCSAGGCRNYPDTFWTNPQYRLKLLEEDDDPEDEEVICSFLVALMQKNRRKERKLGANLYTIGFAIYEVPKEMHGTKHHLQKDFFLYNASKARSKTYINMREISERFRLPPSEYVIIPSTYEPHQEGEFILRVFSEKRSLSEEVENMIEADRPSKKKKGKPIIFVSDRANSNKELTTDEDAGKDGEKTHVDEKKRSSAKAREKSEEETQFRNIFRQIAGDDMEINAEELRNVLNNVVKKHKDLKTEGFELESCRSMIALMDTDGSGKINFDEFRHLWDKIKSWQKIFKHYDADHSGTINSYEMRNAVKDAGFRLNNQLYDIITMRYADKNMNIDFDSFICCFVRLDAMFRAFHAFDKDGDGIIKLNVLEWLQLTMYA", "length": 810, "header": "tr|A0A1D5PLJ8-1|A0A1D5PLJ8_CHICK Isoform 1 of Calpain-3 OS=Gallus gallus OX=9031 GN=CAPN3 PE=3 SV=1 CANONICAL=A0A1D5PLJ8-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PLJ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLJ8/entry#A0A1D5PLJ8-1", "sequence": { "sequence": "MPSAINAAVAQQTAAGSVPSTTSTTTEGTGGGTGGIYSAIISRNQPIIKVKEKTYEELHKKCLEENILYEDPDFPPNETSLFYSQKVPIKFEWKRPREICENPRFIIGGANRTDICQGELGDCWFLAAIACLTLNKKLLCRVIPHDQSFIQNYAGIFHFQFWRYGDWVDVIIDDCLPTYNNQLVFTKSSQRNEFWSALLEKAYAKLHGSYEALKGGNTTEAMEDFTGGVTEFYEIKDAPKDIYKIMKHAIARGSLMASSIDDNLGFSYGAAPRSDIGELIARMVKNLENAQMTYSTVDYQGTDERPAWTIMPMQYETRMSCGLVKGHAYSVTAVEETTYKGEKMRLVRLRNPWGQVEWNGPWSDKSEEWNFIDEEEKTRLQHKIAEDGEFWISFEDFMRHFTKLEICNLTPDTLEADKLQTWTVSVNEGRWVRGCSAGGCRNYPDTFWTNPQYRLKLLEEDDDPEDEEVICSFLVALMQKNRRKERKLGANLYTIGFAIYEVPKEMHGTKHHLQKDFFLYNASKARSKTYINMREISERFRLPPSEYVIIPSTYEPHQEGEFILRVFSEKRSLSEEVENMIEADRPSKKKKGKPIIFVSDRANSNKELTTDEDAGKDGEKTHVDEKKRSSAKAREKSEEETQFRNIFRQIAGDDMEINAEELRNVLNNVVKKHKDLKTEGFELESCRSMIALMDTDGSGKINFDEFRHLWDKIKSWQKIFKHYDADHSGTINSYEMRNAVKDAGFRLNNQLYDIITMRYADKNMNIDFDSFICCFVRLDAMFRAFHAFDKDGDGIIKLNVLEWLQLTMYA", "length": 810, "header": "tr|A0A1D5PLJ8-1|A0A1D5PLJ8_CHICK Isoform 1 of Calpain-3 OS=Gallus gallus OX=9031 GN=CAPN3 PE=3 SV=1 CANONICAL=A0A1D5PLJ8-1" }, "locus": { "chromosome": "5", "start_pos": 25193301, "end_pos": 25170308, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010047044.1", "url": "https://www.ensembl.org/id/ENSGALT00010047044.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027940.1", "url": "https://www.ensembl.org/id/ENSGALP00010027940.1" } ] } }, { "isoform_ac": "A0A1L1RQ67-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLJ8/entry#A0A1L1RQ67-1", "sequence": { "sequence": "MPSAINAAVAQQTAAGSVPSTTSTTTEGTGGGTGGIYSAIISRNQPIIKVKEKTYEELHKKCLEENILYEDPDFPPNETSLFYSQKVPIKFEWKRPREICENPRFIIGGANRTDICQGELGDCWFLAAIACLTLNKKLLCRVIPHDQSFIQNYAGIFHFQFWRYGDWVDVIIDDCLPTYNNQLVFTKSSQRNEFWSALLEKAYAKLHGSYEALKGGNTTEAMEDFTGGVTEFYEIKDAPKDIYKIMKHAIARGSLMASSIDDNLGFSYGAAPRSDIGELIARMVKNLENAQMTYSTVDYQGTDERPAWTIMPMQYETRMSCGLVKGHAYSVTAVEETTYKGEKMRLVRLRNPWGQVEWNGPWSDKSEEWNFIDEEEKTRLQHKIAEDGEFWISFEDFMRHFTKLEICNLTPDTLEADKLQTWTVSVNEGRWVRGCSAGGCRNYPDTFWTNPQYRLKLLEEDDDPEDEEVICSFLVALMQKNRRKERKLGANLYTIGFAIYEVPKEMHGTKHHLQKDFFLYNASKARSKTYINMREISERFRLPPSEYVIIPSTYEPHQEGEFILRVFSEKRSLSEEVENMIEADRPSKKKKGKRSSAKAREKSEEETQFRNIFRQIAGDDMEINAEELRNVLNNVVKKHKDLKTEGFELESCRSMIALMDTDGSGKINFDEFRHLWDKIKSWQKIFKHYDADHSGTINSYEMRNAVKDAGFRLNNQLYDIITMRYADKNMNIDFDSFICCFVRLDAMFRAFHAFDKDGDGIIKLNVLEWLQLTMYA", "length": 776, "header": "tr|A0A1L1RQ67-1|A0A1D5PLJ8_CHICK Computationally mapped isoform of Calpain-3 OS=Gallus gallus OX=9031 GN=CAPN3 PE=3 SV=2 CANONICAL=A0A1D5PLJ8-1" }, "locus": { "chromosome": "5", "start_pos": 25193301, "end_pos": 25170308, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010047063.1", "url": "https://www.ensembl.org/id/ENSGALT00010047063.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027949.1", "url": "https://www.ensembl.org/id/ENSGALP00010027949.1" } ] } }, { "isoform_ac": "A0A8V0ZBA6-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLJ8/entry#A0A8V0ZBA6-1", "sequence": { "sequence": "MPSAINAAVAQQTAAGSVPSTTSTTTEGTGGGTGGIYSAIISRNQPIIKVKEKTYEELHKKCLEENILYEDPDFPPNETSLFYSQKVPIKFEWKRPREICENPRFIIGGANRTDICQGELGDCWFLAAIACLTLNKKLLCRVIPHDQSFIQNYAGIFHFQFWRYGDWVDVIIDDCLPTYNNQLVFTKSSQRNEFWSALLEKAYAKLHGSYEALKGGNTTEAMEDFTGGVTEFYEIKDAPKDIYKIMKHAIARGSLMASSIDDNLGFSYGAAPRSDIGELIARMVKNLENAQMTYSTVDYQGTDERPAWTIMPMQYETRMSCGLVKGHAYSVTAVEETTYKGEKMRLVRLRNPWGQVEWNGPWSDKSEEWNFIDEEEKTRLQHKIAEDGEFWISFEDFMRHFTKLEICNLTPDTLEADKLQTWTVSVNEGRWVRGCSAGGCRNYPDTFWTNPQYRLKLLEEDDDPEDEEVICSFLVALMQKNRRKERKLGANLYTIGFAIYEVPMHGTKHHLQKDFFLYNASKARSKTYINMREISERFRLPPSEYVIIPSTYEPHQEGEFILRVFSEKRSLSEEVENMIEADRPSPIIFVSDRANSNKELTTDEDAGKDGEKTHVDEKKRSSAKAREKSEEETQFRNIFRQIAGDDMEINAEELRNVLNNVVKKHKDLKTEGFELESCRSMIALMDTDGSGKINFDEFRHLWDKIKSWQKIFKHYDADHSGTINSYEMRNAVKDAGFRLNNQLYDIITMRYADKNMNIDFDSFICCFVRLDAMFRAFHAFDKDGDGIIKLNVLEWLQLTMYA", "length": 802, "header": "tr|A0A8V0ZBA6-1|A0A1D5PLJ8_CHICK Computationally mapped isoform of Calpain-3 OS=Gallus gallus OX=9031 GN=CAPN3 PE=3 SV=1 CANONICAL=A0A1D5PLJ8-1" }, "locus": { "chromosome": "5", "start_pos": 25193301, "end_pos": 25170308, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010047054.1", "url": "https://www.ensembl.org/id/ENSGALT00010047054.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027945.1", "url": "https://www.ensembl.org/id/ENSGALP00010027945.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "Identification and association of the single nucleotide polymorphisms in calpain3 (CAPN3) gene with carcass traits in chickens.", "journal": "BMC genetics", "date": "2009-03-05", "authors": "Zhang Zeng-Rong, Liu Yi-Ping, Yao Yong-Gang, Jiang Xiao-Song, Du Hua-Rui, Zhu Qing", "evidence": [ { "database": "RefSeq", "id": "NP_001004405", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001004405" } ], "reference": [ { "type": "PubMed", "id": "19265533", "url": "https://glygen.org/publication/PubMed/19265533" } ] }, { "title": "Characterization of the expression profile of calpain-3 (CAPN3) gene in chicken.", "journal": "Molecular biology reports", "date": "2012-04", "authors": "Zhang Zeng-Rong, Zhu Qing, Yao Yong-Gang, Jiang Xiao-Song, Du Hua-Rui, Liu Yi-Ping", "evidence": [ { "database": "RefSeq", "id": "NP_001004405", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001004405" } ], "reference": [ { "type": "PubMed", "id": "21713405", "url": "https://glygen.org/publication/PubMed/21713405" } ] }, { "title": "The scaffolding protein calpain-3 has multiple distributions in embryonic chick muscle cells and it is essential for the formation of muscle fibers.", "journal": "Tissue & cell", "date": "2020-12", "authors": "de Andrade Rosa Ivone, Corr\u00eaa Stephany, Costa Manoel Luis, Mermelstein Claudia", "evidence": [ { "database": "RefSeq", "id": "NP_001004405", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001004405" } ], "reference": [ { "type": "PubMed", "id": "32932207", "url": "https://glygen.org/publication/PubMed/32932207" } ] } ], "pathway": [ { "id": "gga:423233", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423233", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "P16259-1", "protein_name": "Calpain-3", "gene_name": "Capn3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPTVISPTVAPRTGAEPRSPGPVPHPAQGKTTEAGGGHPGGIYSAIISRNFPIIGVKEKTFEQLHKKCLEKKVLYLDPEFPPDETSLFYSQKFPIQFVWKRPPEICENPRFIIGGANRTDICQGDLGDCWLLAAIACLTLNERLLFRVIPHDQSFTENYAGIFHFQFWRYGDWVDVVIDDCLPTYNNQLVFTKSNHRNEFWSALLEKAYAKLHGSYEALKGGNTTEAMEDFTGGVTEFFEIKDAPSDMYKIMRKAIERGSLMGCSIDDGTNMTYGTSPSGLNMGELIARMVRNMDNSLLRDSDLDPRASDDRPSRTIVPVQYETRMACGLVKGHAYSVTGLEEALFKGEKVKLVRLRNPWGQVEWNGSWSDGWKDWSFVDKDEKARLQHQVTEDGEFWMSYDDFVYHFTKLEICNLTADALESDKLQTWTVSVNEGRWVRGCSAGGCRNFPDTFWTNPQYRLKLLEEDDDPDDSEVICSFLVALMQKNRRKDRKLGANLFTIGFAIYEVPKEMHGNKQHLQKDFFLYNASKARSKTYINMREVSQRFRLPPSEYVIVPSTYEPHQEGEFILRVFSEKRNLSEEAENTISVDRPVKKKKNKPIIFVSDRANSNKELGVDQEAEEGKDKTGPDKQGESPQPRPGHTDQESEEQQQFRNIFRQIAGDDMEICADELKNVLNTVVNKHKDLKTQGFTLESCRSMIALMDTDGSGRLNLQEFHHLWKKIKAWQKIFKHYDTDHSGTINSYEMRNAVNDAGFHLNSQLYDIITMRYADKHMNIDFDSFICCFVRLEGMFRAFHAFDKDGDGIIKLNVLEWLQLTMYA", "length": 821 }, "evidence": [ { "id": "A0A1D5PLJ8", "url": "https://omabrowser.org/oma/group/A0A1D5PLJ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P20807-1", "protein_name": "Calpain-3", "gene_name": "CAPN3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPTVISASVAPRTAAEPRSPGPVPHPAQSKATEAGGGNPSGIYSAIISRNFPIIGVKEKTFEQLHKKCLEKKVLYVDPEFPPDETSLFYSQKFPIQFVWKRPPEICENPRFIIDGANRTDICQGELGDCWFLAAIACLTLNQHLLFRVIPHDQSFIENYAGIFHFQFWRYGEWVDVVIDDCLPTYNNQLVFTKSNHRNEFWSALLEKAYAKLHGSYEALKGGNTTEAMEDFTGGVAEFFEIRDAPSDMYKIMKKAIERGSLMGCSIDDGTNMTYGTSPSGLNMGELIARMVRNMDNSLLQDSDLDPRGSDERPTRTIIPVQYETRMACGLVRGHAYSVTGLDEVPFKGEKVKLVRLRNPWGQVEWNGSWSDRWKDWSFVDKDEKARLQHQVTEDGEFWMSYEDFIYHFTKLEICNLTADALQSDKLQTWTVSVNEGRWVRGCSAGGCRNFPDTFWTNPQYRLKLLEEDDDPDDSEVICSFLVALMQKNRRKDRKLGASLFTIGFAIYEVPKEMHGNKQHLQKDFFLYNASKARSKTYINMREVSQRFRLPPSEYVIVPSTYEPHQEGEFILRVFSEKRNLSEEVENTISVDRPVKKKKTKPIIFVSDRANSNKELGVDQESEEGKGKTSPDKQKQSPQPQPGSSDQESEEQQQFRNIFKQIAGDDMEICADELKKVLNTVVNKHKDLKTHGFTLESCRSMIALMDTDGSGKLNLQEFHHLWNKIKAWQKIFKHYDTDQSGTINSYEMRNAVNDAGFHLNNQLYDIITMRYADKHMNIDFDSFICCFVRLEGMFRAFHAFDKDGDGIIKLNVLEWLQLTMYA", "length": 821 }, "evidence": [ { "id": "A0A1D5PLJ8", "url": "https://omabrowser.org/oma/group/A0A1D5PLJ8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q64691-1", "protein_name": "Calpain-3", "gene_name": "Capn3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPTVISPTVAPRTGAEPRSPGPVPHPAQGKTTEAGGGHPSGIYSAIISRNFPIIGVKEKTFEQLRRKCLEKKVLYLDPEFPPDETSLFYSQKFPIQFVWKRPPEICENPRFIIGGANRTDICQGDLGDCWFLAAIACLTLNERLLFRVIPHDQSFTENYAGIFHFQFWRYGDWVDVVIDDCLPTYNNQLVFTKSNHRNEFWSALLEKAYAKLHGSYEALKGGNTTEAMEDFTGGVTEFFEIKDAPSDMYKIMRKAIERGSLMGCSIDDGTNMTYGTSPSGLNMGELIARMVRNMDNSLLRDSDLDPRGSDDRPSRTIVPVQYETRMACGLVKGHAYSVTGLEEALFKGEKVKLVRLRNPWGQVEWNGSWSDGWKDWSFVDKDEKARLQHQVTEDGEFWMSYDDFVYHFTKLEICNLTADALESDKLQTWTVSVNEGRWVRGCSAGGCRNFPDTFWTNPQYRLKLLEEDDDPEDSEVICSFLVALMQKNRRKDRKLGANLFTIGFAIYEVPKEMHGNKQHLQKDFFLYNASKARSKTYINMREVSQRFRLPPSEYVIVPSTYEPHQEGEFILRVFSEKRNLSEEAENTISVDRPVKKKKNKPIIFVSDRANSNKELGVDQEAEEGKDKAGPEKRGETPQPRPGHTDQESEEQQQFRNIFRQIAGDDMEICADELKNVLNTVVNKHKDLKTQGFTLESCRSMIALMDTDGSGRLNLQEFHHLWKKIKAWQKIFKHYDTDHSGTINSYEMRNAVNDAGFHLNSQLYDIITMRYADKHMNIDFDSFICCFVRLEGMFRAFNAFDKDGDGIIKLNVLEWLQLTMYA", "length": 821 }, "evidence": [ { "id": "A0A1D5PLJ8", "url": "https://omabrowser.org/oma/group/A0A1D5PLJ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VT65-1", "protein_name": "Calpain-B", "gene_name": "CalpB", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MYGIDNYPKNYHASGIGLVNLAALGYSKNEVSGGNEGGGAPKPKAGLYPSLPYPSSESVGGMPYVVKQTSHAQNASYAGPTMGMGMPVPEAPSAPAPYPSATPYPGSGLYPSLPSANVSSLPYPTAPMAPYPTGMPYPTGMPQPNLPYPAAPLAPYPSAMPGLPGMPMPYAPMPTSPAPQHNIGFPALPYPTAPPPESAPTQEEEPSVGVAELSFTSVKVPENQNMFWMGRKATSARQNSVSKGDFQSLRDSCLANGTMFEDPDFPATNASLMYSRRPDRYYEWLRPGDIADDPQFFVEGYSRFDVQQGELGDCWLLAAAANLTQDSTLFFRVIPPDQDFQENYAGIFHFKFWQYGKWVEVVIDDRLPTYNGELIYMHSTEKNEFWSALLEKAYAKLHGSYEALKGGTTCEAMEDFTGGVTEWYDIKEAPPNLFSIMMKAAERGSMMGCSLEPDPHVLEAETPQGLIRGHAYSITKVCLMDISTPNRQGKLPMIRMRNPWGNDAEWSGPWSDSSPEWRFIPEHTKEEIGLNFDRDGEFWMSFQDFLNHFDRVEICNLSPDSLTEDQQHSSRRKWEMSMFEGEWTSGVTAGGCRNFLETFWHNPQYIISLEDPDDEDDDGKCTAIVALMQKNRRSKRNVGIDCLTIGFAIYHLTDRDMQVKPQGLNFFKYRASVARSPHFINTREVCARFKLPPGHYLIVPSTFDPNEEGEFIIRVFSETRNNMEENDDEVGFGETDDRIAPSLPPPTPKEEDDPQRIALRRLFDSVAGSDEEVDWQELKRILDHSMRDVMVGSDGFSKDAVRSMVAMLDKDRSGRLGFEEFEALLTDIAKWRAVFKLYDTRRTGSIDGFHLRGALNSAGYHLNNRLLNALAHRYGSREGQIPFDDFLMCAIKVRTFIEMFRERDTDNSDTAFFNLDDWLERTIYS", "length": 925 }, "evidence": [ { "id": "A0A1D5PLJ8", "url": "https://omabrowser.org/oma/group/A0A1D5PLJ8/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "molecular adaptor activity", "id": "GO:0060090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060090", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PLJ8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLJ8" } ], "pmid": "" }, { "name": "calcium-dependent cysteine-type endopeptidase activity", "id": "GO:0004198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004198", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PLJ8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLJ8" } ], "pmid": "" }, { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PLJ8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLJ8" } ], "pmid": "" }, { "name": "structural constituent of muscle", "id": "GO:0008307", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008307", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PLJ8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLJ8" } ], "pmid": "" }, { "name": "titin binding", "id": "GO:0031432", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031432", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PLJ8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLJ8" } ], "pmid": "" }, { "name": "sodium ion binding", "id": "GO:0031402", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031402", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PLJ8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLJ8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PLJ8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLJ8" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PLJ8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLJ8" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PLJ8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLJ8" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PLJ8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLJ8" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PLJ8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLJ8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 20, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PLJ8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLJ8" } ], "pmid": "" }, { "name": "negative regulation of apoptotic process", "id": "GO:0043066", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043066", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PLJ8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLJ8" } ], "pmid": "" }, { "name": "negative regulation of DNA-templated transcription", "id": "GO:0045892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045892", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PLJ8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLJ8" } ], "pmid": "" }, { "name": "cellular response to calcium ion", "id": "GO:0071277", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071277", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PLJ8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLJ8" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PLJ8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLJ8" } ], "pmid": "" }, { "name": "positive regulation of release of sequestered calcium ion into cytosol", "id": "GO:0051281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051281", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PLJ8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLJ8" } ], "pmid": "" }, { "name": "protein localization to membrane", "id": "GO:0072657", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072657", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PLJ8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLJ8" } ], "pmid": "" }, { "name": "protein catabolic process", "id": "GO:0030163", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030163", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PLJ8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLJ8" } ], "pmid": "" }, { "name": "positive regulation of proteolysis", "id": "GO:0045862", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045862", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PLJ8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLJ8" } ], "pmid": "" }, { "name": "regulation of canonical NF-kappaB signal transduction", "id": "GO:0043122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043122", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PLJ8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLJ8" } ], "pmid": "" }, { "name": "protein destabilization", "id": "GO:0031648", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031648", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PLJ8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLJ8" } ], "pmid": "" }, { "name": "cellular response 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This record is derived from a genomic sequence (NC_052544.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Dec 16, 2011 this sequence version replaced XP_001233249.1. 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domain binding", "id": "GO:0042169", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042169", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PLN4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLN4" } ], "pmid": "" }, { "name": "signaling adaptor activity", "id": "GO:0035591", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035591", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PLN4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLN4" } ], "pmid": "" }, { "name": "ubiquitin binding", "id": "GO:0043130", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043130", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PLN4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLN4" } ], "pmid": "" }, { "name": "K63-linked polyubiquitin modification-dependent protein binding", "id": "GO:0070530", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070530", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PLN4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLN4" } ], "pmid": "" }, { "name": "ionotropic glutamate receptor binding", "id": "GO:0035255", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035255", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PLN4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLN4" } ], "pmid": "" }, { "name": "signaling receptor activity", "id": "GO:0038023", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038023", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PLN4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLN4" } ], "pmid": "" }, { "name": "molecular condensate scaffold activity", "id": "GO:0140693", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140693", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PLN4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLN4" } ], "pmid": "" }, { "name": "protein sequestering activity", "id": "GO:0140311", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140311", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PLN4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLN4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 20, "go_terms": [ { "name": "temperature homeostasis", "id": "GO:0001659", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001659", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PLN4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLN4" } ], "pmid": "" }, { "name": "positive regulation of long-term synaptic potentiation", "id": "GO:1900273", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900273", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PLN4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLN4" } ], "pmid": "" }, { "name": "energy homeostasis", "id": "GO:0097009", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097009", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PLN4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLN4" } ], "pmid": "" }, { "name": "endosome organization", "id": "GO:0007032", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007032", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PLN4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLN4" } ], "pmid": "" }, { "name": "positive regulation of protein localization to plasma membrane", "id": "GO:1903078", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903078", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PLN4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLN4" } ], "pmid": "" }, { "name": "positive regulation of autophagy", "id": "GO:0010508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010508", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PLN4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLN4" } ], "pmid": "" }, { "name": "negative regulation of protein ubiquitination", "id": "GO:0031397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031397", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PLN4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLN4" } ], "pmid": "" }, { "name": "protein catabolic process", "id": "GO:0030163", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030163", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PLN4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLN4" } ], "pmid": "" }, { "name": "mitophagy", "id": "GO:0000423", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000423", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PLN4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLN4" } ], "pmid": "" }, { "name": "regulation of canonical NF-kappaB signal transduction", "id": "GO:0043122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043122", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PLN4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLN4" } ], "pmid": "" }, { "name": "response to mitochondrial depolarisation", "id": "GO:0098780", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098780", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PLN4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLN4" } ], "pmid": "" }, { "name": "aggrephagy", "id": "GO:0035973", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035973", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PLN4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLN4" } ], "pmid": "" }, { "name": "protein localization to perinuclear region of cytoplasm", "id": "GO:1905719", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905719", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PLN4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLN4" } ], "pmid": "" }, { "name": "protein targeting to vacuole involved in autophagy", "id": "GO:0071211", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071211", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PLN4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLN4" } ], "pmid": "" }, { "name": "negative regulation of toll-like receptor 4 signaling pathway", "id": "GO:0034144", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034144", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PLN4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLN4" } ], "pmid": "" }, { "name": "regulation of protein complex stability", "id": "GO:0061635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061635", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PLN4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLN4" } ], "pmid": "" }, { "name": "protein import into nucleus", "id": "GO:0006606", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006606", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PLN4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLN4" } ], "pmid": "" }, { "name": "pexophagy", "id": "GO:0000425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000425", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PLN4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLN4" } ], "pmid": "" }, { "name": "negative regulation of ferroptosis", "id": "GO:0110076", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0110076", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PLN4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLN4" } ], "pmid": "" }, { "name": "membraneless organelle assembly", "id": "GO:0140694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140694", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PLN4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLN4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 12, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PLN4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLN4" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PLN4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLN4" } ], "pmid": "" }, { "name": "sarcomere", "id": "GO:0030017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030017", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PLN4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLN4" } ], "pmid": "" }, { "name": "P-body", "id": "GO:0000932", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000932", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PLN4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLN4" } ], "pmid": "" }, { "name": "PML body", "id": "GO:0016605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016605", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PLN4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLN4" } ], "pmid": "" }, { "name": "phagophore assembly site", "id": "GO:0000407", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000407", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PLN4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLN4" } ], "pmid": "" }, { "name": "sperm midpiece", "id": "GO:0097225", "url": 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"binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 232, "end_pos": 234 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { 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"total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A1D5PM19-1", "uniprot_ac": "A0A1D5PM19", "uniprot_id": "A0A1D5PM19_CHICK", "mass": { "chemical_mass": 226638.0, "monoisotopic_mass": 226638.0 }, "refseq": { "ac": "XP_040527622", "name": "myosin-9 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040527622" }, "gene_names": [ { "name": "MYH9", "type": "recommended", "evidence": [ { "id": "A0A1D5PM19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PM19" } ] }, { "name": "MYH9", 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This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040527622", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040527622" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PM19", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PM19" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MYH9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PM19", "locus": { "chromosome": "1", "start_pos": 51863042, "end_pos": 51794919, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010015031", "url": "https://www.ensembl.org/id/ENSGALG00010015031" } ] } } ], "crossref": [ { "id": "ENSGALG00000043092", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000043092", 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"MAQRDADKYLYVDKNIINNPLTQADWAAKKLVWVPSEKSGFEAASLKEEVGDEAIVELAENGKKVKVNKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLKERYYSGLIYTYSGLFCVVINPYKNLPIYSEEIVEMYKGKKRHEMPPHIYAITDTAYRSMMQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSHKSKKDQGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVNGYIVGANIETYLLEKSRAIRQAKEERTFHIFYYLLSGAGEHLKTDLLLEPYNKYRFLSNGHVTIPGQQDKDMFQETMEAMRIMGIPDEEQIGLLKVISGVLQLGNIVFKKERNTDQASMPDNTAAQKVSHLLGINVTDFTRGILTPRIKVGRDYVQKAQTKEQADFAIEALAKATYERMFRWLVMRINKALDKTKRQGASFIGILDIAGFEIFELNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIDLIEKPAGPPGILALLDEECWFPKATDKSFVEKVVQEQGTHPKFQKPKQLKDKADFCIIHYAGKVDYKADEWLMKNMDPLNDNIATLLHQSSDKFVSELWKDVDRIVGLDQVAGMSETALPGAFKTRKGMFRTVGQLYKEQLAKLMATLRNTNPNFVRCIIPNHEKKAGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRVVFQEFRQRYEILTPNAIPKGFMDGKQACVLMIKALELDSNLYRIGQSKVFFRAGVLAHLEEERDLKITDVIIGFQACCRGYLARKAFAKRQQQLTAMKVLQRNCAAYLKLRNWQWWRLFTKVKPLLQVSRQEEEMMAKEEELIKVKEKQLAAENRLSEMETFQAQLMAEKMQLQEQLQAEAELCAEAEEIRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEDVIVLEDQNLKLAKEKKLLEDRMSEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSSDLHDQIAELQAQIAELKIQLSKKEEELQAALARVEEEAAQKNMALKKIRELESQITELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVTVLKKTLEDEAKTHEAQIQEMRQKHSQAIEELAEQLEQTKRVKANLEKAKQALESERAELSNEVKVLLQGKGDAEHKRKKVDAQLQELQVKFTEGERVKTELAERVNKLQVELDNVTGLLNQSDSKSIKLAKDFSALESQLQDTQELLQEETRLKLSFSTKLKQTEDEKNALKEQLEEEEEAKRNLEKQISVLQQQAVEARKKMDDGLGCLEIAEEAKKKLQKDLESLTQRYEEKIAAYDKLEKTKTRLQQELDDIAVDLDHQRQTVSNLEKKQKKFDQLLAEEKNISAKYAEERDRAEAEAREKETKALSLARALEEAIEQKAELERVNKQFRTEMEDLMSSKDDVGKSVHELEKAKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNQQAMKAQFDRDLLGRDEQNEEKRKQLIRQVREMEVELEDERKQRSIAVAARKKLELDLKDLESHIDTANKNRDEAIKQLRKLQAQMKDYMRELEDTRTSREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALAMEEKRRLEARIAQLEEELEEEQGNTEIINDRLKKANLQIDQMNADLNAERSNAQKNENARQQMERQNKELKLKLQEMESAVKSKYKATITALEAKIVQLEEQLDMETKERQAASKQVRRAEKKLKDILLQVDDERRNAEQFKDQADKANMRLKQLKRQLEEAEEEAQRANASRRKLQRELDDATETADAMNREVSSLKSKLRRGDLPFVVTRRLVRKGTGECSDEEVDGKAEAGDAKATE", "length": 1960, "header": "tr|A0A1D5PM19-1|A0A1D5PM19_CHICK Isoform 1 of Myosin-9 OS=Gallus gallus OX=9031 GN=MYH9 PE=1 SV=2 CANONICAL=A0A1D5PM19-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PM19-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PM19/entry#A0A1D5PM19-1", "sequence": { "sequence": "MAQRDADKYLYVDKNIINNPLTQADWAAKKLVWVPSEKSGFEAASLKEEVGDEAIVELAENGKKVKVNKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLKERYYSGLIYTYSGLFCVVINPYKNLPIYSEEIVEMYKGKKRHEMPPHIYAITDTAYRSMMQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSHKSKKDQGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVNGYIVGANIETYLLEKSRAIRQAKEERTFHIFYYLLSGAGEHLKTDLLLEPYNKYRFLSNGHVTIPGQQDKDMFQETMEAMRIMGIPDEEQIGLLKVISGVLQLGNIVFKKERNTDQASMPDNTAAQKVSHLLGINVTDFTRGILTPRIKVGRDYVQKAQTKEQADFAIEALAKATYERMFRWLVMRINKALDKTKRQGASFIGILDIAGFEIFELNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIDLIEKPAGPPGILALLDEECWFPKATDKSFVEKVVQEQGTHPKFQKPKQLKDKADFCIIHYAGKVDYKADEWLMKNMDPLNDNIATLLHQSSDKFVSELWKDVDRIVGLDQVAGMSETALPGAFKTRKGMFRTVGQLYKEQLAKLMATLRNTNPNFVRCIIPNHEKKAGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRVVFQEFRQRYEILTPNAIPKGFMDGKQACVLMIKALELDSNLYRIGQSKVFFRAGVLAHLEEERDLKITDVIIGFQACCRGYLARKAFAKRQQQLTAMKVLQRNCAAYLKLRNWQWWRLFTKVKPLLQVSRQEEEMMAKEEELIKVKEKQLAAENRLSEMETFQAQLMAEKMQLQEQLQAEAELCAEAEEIRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEDVIVLEDQNLKLAKEKKLLEDRMSEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSSDLHDQIAELQAQIAELKIQLSKKEEELQAALARVEEEAAQKNMALKKIRELESQITELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVTVLKKTLEDEAKTHEAQIQEMRQKHSQAIEELAEQLEQTKRVKANLEKAKQALESERAELSNEVKVLLQGKGDAEHKRKKVDAQLQELQVKFTEGERVKTELAERVNKLQVELDNVTGLLNQSDSKSIKLAKDFSALESQLQDTQELLQEETRLKLSFSTKLKQTEDEKNALKEQLEEEEEAKRNLEKQISVLQQQAVEARKKMDDGLGCLEIAEEAKKKLQKDLESLTQRYEEKIAAYDKLEKTKTRLQQELDDIAVDLDHQRQTVSNLEKKQKKFDQLLAEEKNISAKYAEERDRAEAEAREKETKALSLARALEEAIEQKAELERVNKQFRTEMEDLMSSKDDVGKSVHELEKAKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNQQAMKAQFDRDLLGRDEQNEEKRKQLIRQVREMEVELEDERKQRSIAVAARKKLELDLKDLESHIDTANKNRDEAIKQLRKLQAQMKDYMRELEDTRTSREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALAMEEKRRLEARIAQLEEELEEEQGNTEIINDRLKKANLQIDQMNADLNAERSNAQKNENARQQMERQNKELKLKLQEMESAVKSKYKATITALEAKIVQLEEQLDMETKERQAASKQVRRAEKKLKDILLQVDDERRNAEQFKDQADKANMRLKQLKRQLEEAEEEAQRANASRRKLQRELDDATETADAMNREVSSLKSKLRRGDLPFVVTRRLVRKGTGECSDEEVDGKAEAGDAKATE", "length": 1960, "header": "tr|A0A1D5PM19-1|A0A1D5PM19_CHICK Isoform 1 of Myosin-9 OS=Gallus gallus OX=9031 GN=MYH9 PE=1 SV=2 CANONICAL=A0A1D5PM19-1" }, "locus": { "chromosome": "1", "start_pos": 51861968, "end_pos": 51809282, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036169.1", "url": "https://www.ensembl.org/id/ENSGALT00010036169.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021016.1", "url": "https://www.ensembl.org/id/ENSGALP00010021016.1" } ] } }, { "isoform_ac": "A0A8V0YJF4-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PM19/entry#A0A8V0YJF4-1", "sequence": { "sequence": "MAQRDADKYLYVDKNIINNPLTQADWAAKKLVWVPSEKSGFEAASLKEEVGDEAIVELAENGKKVKVNKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLKERYYSGLIYTYSGLFCVVINPYKNLPIYSEEIVEMYKGKKRHEMPPHIYAITDTAYRSMMQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSHKSKKDQGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVNGYIVGANIETYLLEKSRAIRQAKEERTFHIFYYLLSGAGEHLKTDLLLEPYNKYRFLSNGHVTIPGQQDKDMFQETMEAMRIMGIPDEEQIGLLKVISGVLQLGNIVFKKERNTDQASMPDNTAAQKVSHLLGINVTDFTRGILTPRIKVGRDYVQKAQTKEQADFAIEALAKATYERMFRWLVMRINKALDKTKRQGASFIGILDIAGFEIFELNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIDLIEKPAGPPGILALLDEECWFPKATDKSFVEKVVQEQGTHPKFQKPKQLKDKADFCIIHYAGKVDYKADEWLMKNMDPLNDNIATLLHQSSDKFVSELWKDVDRIVGLDQVAGMSETALPGAFKTRKGMFRTVGQLYKEQLAKLMATLRNTNPNFVRCIIPNHEKKAGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRVVFQEFRQRYEILTPNAIPKGFMDGKQACVLMIKALELDSNLYRIGQSKVFFRAGVLAHLEEERDLKITDVIIGFQACCRGYLARKAFAKRQQQLTAMKVLQRNCAAYLKLRNWQWWRLFTKVKPLLQVSRQEEEMMAKEEELIKVKEKQLAAENRLSEMETFQAQLMAEKMQLQEQLQAEAELCAEAEEIRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEDVIVLEDQNLKLAKEKKLLEDRMSEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQKHSQAIEELAEQLEQTKRVKANLEKAKQALESERAELSNEVKVLLQGKGDAEHKRKKVDAQLQELQVKFTEGERVKTELAERVNKLQVELDNVTGLLNQSDSKSIKLAKDFSALESQLQDTQELLQEETRLKLSFSTKLKQTEDEKNALKEQLEEEEEAKRNLEKQISVLQQQAVEARKKMDDGLGCLEIAEEAKKKLQKDLESLTQRYEEKIAAYDKLEKTKTRLQQELDDIAVDLDHQRQTVSNLEKKQKKFDQLLAEEKNISAKYAEERDRAEAEAREKETKALSLARALEEAIEQKAELERVNKQFRTEMEDLMSSKDDVGKSVHELEKAKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNQQAMKAQFDRDLLGRDEQNEEKRKQLIRQVREMEVELEDERKQRSIAVAARKKLELDLKDLESHIDTANKNRDEAIKQLRKLQAQMKDYMRELEDTRTSREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALAMEEKRRLEARIAQLEEELEEEQGNTEIINDRLKKANLQIDQMNADLNAERSNAQKNENARQQMERQNKELKLKLQEMESAVKSKYKATITALEAKIVQLEEQLDMETKERQAASKQVRRAEKKLKDILLQVDDERRNAEQFKDQADKANMRLKQLKRQLEEAEEEAQRANASRRKLQRELDDATETADAMNREVSSLKSKLRRGDLPFVVTRRLVRKGTGECSDEEVDGKAEAGDAKATE", "length": 1810, "header": "tr|A0A8V0YJF4-1|A0A8V0YJF4_CHICK Computationally mapped isoform of Myosin-9 OS=Gallus gallus OX=9031 GN=MYH9 PE=1 SV=1 CANONICAL=A0A1D5PM19-1" }, "locus": { "chromosome": "1", "start_pos": 51861968, "end_pos": 51809282, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036230.1", "url": "https://www.ensembl.org/id/ENSGALT00010036230.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021061.1", "url": "https://www.ensembl.org/id/ENSGALP00010021061.1" } ] } }, { "isoform_ac": "A0A8V0YQT5-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PM19/entry#A0A8V0YQT5-1", "sequence": { "sequence": "MAQRDADKYLYVDKNIINNPLTQADWAAKKLVWVPSEKSGFEAASLKEEVGDEAIVELAENGKKVKVNKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLKERYYSGLIYTYSGLFCVVINPYKNLPIYSEEIVEMYKGKKRHEMPPHIYAITDTAYRSMMQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSHKSKKDQLYPRR", "length": 209, "header": "tr|A0A8V0YQT5-1|A0A8V0YQT5_CHICK Computationally mapped isoform of Myosin, heavy chain 9, non-muscle OS=Gallus gallus OX=9031 GN=MYH9 PE=3 SV=1 CANONICAL=A0A1D5PM19-1" }, "locus": { "chromosome": "1", "start_pos": 51826376, "end_pos": 51809282, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036153.1", "url": "https://www.ensembl.org/id/ENSGALT00010036153.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021005.1", "url": "https://www.ensembl.org/id/ENSGALP00010021005.1" } ] } }, { "isoform_ac": "A0A8V0YQT7-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PM19/entry#A0A8V0YQT7-1", "sequence": { "sequence": "MAQRDADKYLYVDKNIINNPLTQADWAAKKLVWVPSEKSGFEAASLKEEVGDEAIVELAENGKKVKVNKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLKERYYSGLIYTYSGLFCVVINPYKNLPIYSEEIVEMYKGKKRHEMPPHIYAITDTAYRSMMQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSHKSKKDQGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVNGYIVGANIETYLLEKSRAIRQAKEERTFHIFYYLLSGAGEHLKTDLLLEPYNKYRFLSNGHVTIPGQQDKDMFQETMEAMRIMGIPDEEQIGLLKVISGVLQLGNIVFKKERNTDQASMPDNTAAQKVSHLLGINVTDFTRGILTPRIKVGRDYVQKAQTKEQADFAIEALAKATYERMFRWLVMRINKALDKTKRQGASFIGILDIAGFEIFELNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIDLIEKPAGPPGILALLDEECWFPKATDKSFVEKVVQEQGTHPKFQKPKQLKDKADFCIIHYAGKVDYKADEWLMKNMDPLNDNIATLLHQSSDKFVSELWKDVDRIVGLDQVAGMSETALPGAFKTRKGMFRTVGQLYKEQLAKLMATLRNTNPNFVRCIIPNHEKKAGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRVVFQEFRQRYEILTPNAIPKGFMDGKQACVLMIKALELDSNLYRIGQSKVFFRAGVLAHLEEERDLKITDVIIGFQACCRGYLARKAFAKRQQQLTAMKVLQRNCAAYLKLRNWQWWRLFTKVKPLLQVSRQEEEMMAKEEELIKVKEKQLAAENRLSEMETFQAQLMAEKMQLQEQLQAEAELCAEAEEIRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEDVIVLEDQNLKLAKEKKLLEDRMSEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEEEAAQKNMALKKIRELESQITELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVTVLKKTLEDEAKTHEAQIQEMRQKHSQAIEELAEQLEQTKRVKANLEKAKQALESERAELSNEVKVLLQGKGDAEHKRKKVDAQLQELQVKFTEGERVKTELAERVNKLQVELDNVTGLLNQSDSKSIKLAKDFSALESQLQDTQELLQEETRLKLSFSTKLKQTEDEKNALKEQLEEEEEAKRNLEKQISVLQQQAVEARKKMDDGLGCLEIAEEAKKKLQKDLESLTQRYEEKIAAYDKLEKTKTRLQQELDDIAVDLDHQRQTVSNLEKKQKKFDQLLAEEKNISAKYAEERDRAEAEAREKETKALSLARALEEAIEQKAELERVNKQFRTEMEDLMSSKDDVGKSVHELEKAKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNQQAMKAQFDRDLLGRDEQNEEKRKQLIRQVREMEVELEDERKQRSIAVAARKKLELDLKDLESHIDTANKNRDEAIKQLRKLQAQMKDYMRELEDTRTSREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALAMEEKRRLEARIAQLEEELEEEQGNTEIINDRLKKANLQIDQMNADLNAERSNAQKNENARQQMERQNKELKLKLQEMESAVKSKYKATITALEAKIVQLEEQLDMETKERQAASKQVRRAEKKLKDILLQVDDERRNAEQFKDQADKANMRLKQLKRQLEEAEEEAQRANASRRKLQRELDDATETADAMNREVSSLKSKLRRGDLPFVVTRRLVRKGTGECSDEEVDGKAEAGDAKATE", "length": 1900, "header": "tr|A0A8V0YQT7-1|A0A8V0YQT7_CHICK Computationally mapped isoform of Myosin-9 OS=Gallus gallus OX=9031 GN=MYH9 PE=1 SV=1 CANONICAL=A0A1D5PM19-1" }, "locus": { "chromosome": "1", "start_pos": 51861968, "end_pos": 51809282, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036213.1", "url": "https://www.ensembl.org/id/ENSGALT00010036213.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021053.1", "url": "https://www.ensembl.org/id/ENSGALP00010021053.1" } ] } }, { "isoform_ac": "A0A8V0YQV5-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PM19/entry#A0A8V0YQV5-1", "sequence": { "sequence": "MAQRDADKYLYVDKNIINNPLTQADWAAKKLVWVPSEKSGFEAASLKEEVGDEAIVELAENGKKVKVNKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLKERYYSGLIYTYSGLFCVVINPYKNLPIYSEEIVEMYKGKKRHEMPPHIYAITDTAYRSMMQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSHKSKKDQGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVNGYIVGANIETYLLEKSRAIRQAKEERTFHIFYYLLSGAGEHLKTDLLLEPYNKYRFLSNGHVTIPGQQDKDMFQETMEAMRIMGIPDEEQIGLLKVISGVLQLGNIVFKKERNTDQASMPDNTAAQKVSHLLGINVTDFTRGILTPRIKVGRDYVQKAQTKEQADFAIEALAKATYERMFRWLVMRINKALDKTKRQGASFIGILDIAGFEIFELNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIDLIEKPAGPPGILALLDEECWFPKATDKSFVEKVVQEQGTHPKFQKPKQLKDKADFCIIHYAGKVDYKADEWLMKNMDPLNDNIATLLHQSSDKFVSELWKDVDRIVGLDQVAGMSETALPGAFKTRKGMFRTVGQLYKEQLAKLMATLRNTNPNFVRCIIPNHEKKAGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRVVFQEFRQRYEILTPNAIPKGFMDGKQACVLMIKALELDSNLYRIGQSKVFFRAGVLAHLEEERDLKITDVIIGFQACCRGYLARKAFAKRQQQLTAMKVLQRNCAAYLKLRNWQWWRLFTKVKPLLQVSRQEEEMMAKEEELIKVKEKQLAAENRLSEMETFQAQLMAEKMQLQEQLQAEAELCAEAEEIRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEDVIVLEDQNLKLAKEKKLLEDRMSEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSSDLHDQIAELQAQIAELKIQLSKKEEELQAALARVEEEAAQKNMALKKIRELESQITELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVTVLKKTLEDEAKTHEAQIQEMRQKHSQAIEELAEQLEQTKRVKANLEKAKQALESERAELSNEVKVLLQGKGDAEHKRKKVDAQLQELQVKFTEGERVKTELAERVNKLQVELDNVTGLLNQSDSKSIKLAKDFSALESQLQDTQELLQEETRLKLSFSTKLKQTEDEKNALKEQLEEEEEAKRNLEKQISVLQQQAVEARKKMDDGLGCLEIAEEAKKKLQKDLESLTQRYEEKIAAYDKLEKTKTRLQQELDDIAVDLDHQRQTVSNLEKKQKKFDQLLAEEKNISAKYAEERDRAEAEAREKETKALSLARALEEAIEQKAELERVNKQFRTEMEDLMSSKDDVGKSVHELEKAKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNQQAMKAQFDRDLLGRDEQNEEKRKQLIRQVREMEVELEDERKQRSIAVAARKKLELDLKDLESHIDTANKNRDEAIKQLRKLQAQMKDYMRELEDTRTSREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALAMEEKRRLEEELEEEQGNTEIINDRLKKANLQIDQMNADLNAERSNAQKNENARQQMERQNKELKLKLQEMESAVKSKYKATITALEAKIVQLEEQLDMETKERQAASKQVRRAEKKLKDILLQVDDERRNAEQFKDQADKANMRLKQLKRQLEEAEEEAQRANASRRKLQRELDDATETADAMNREVSSLKSKLRRGDLPFVVTRRLVRKGTGECSDEEVDGKAEAGDAKATE", "length": 1953, "header": "tr|A0A8V0YQV5-1|A0A8V0YQV5_CHICK Computationally mapped isoform of Myosin-9 OS=Gallus gallus OX=9031 GN=MYH9 PE=1 SV=1 CANONICAL=A0A1D5PM19-1" }, "locus": { "chromosome": "1", "start_pos": 51861968, "end_pos": 51809282, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036183.1", "url": "https://www.ensembl.org/id/ENSGALT00010036183.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021030.1", "url": "https://www.ensembl.org/id/ENSGALP00010021030.1" } ] } }, { "isoform_ac": "A0A8V0YQW8-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PM19/entry#A0A8V0YQW8-1", "sequence": { "sequence": "MAQRDADKYLYVDKNIINNPLTQADWAAKKLVWVPSEKSGFEAASLKEEVGDEAIVELAENGKKVKVNKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLKERYYSGLIYTYSGLFCVVINPYKNLPIYSEEIVEMYKGKKRHEMPPHIYAITDTAYRSMMQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSHKSKKDQGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVNGYIVGANIETYLLEKSRAIRQAKEERTFHIFYYLLSGAGEHLKTDLLLEPYNKYRFLSNGHVTIPGQQDKDMFQETMEAMRIMGIPDEEQIGLLKVISGVLQLGNIVFKKERNTDQASMPDNTAAQKVSHLLGINVTDFTRGILTPRIKVGRDYVQKAQTKEQADFAIEALAKATYERMFRWLVMRINKALDKTKRQGASFIGILDIAGFEIFELNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIDLIEKPAGPPGILALLDEECWFPKATDKSFVEKVVQEQGTHPKFQKPKQLKDKADFCIIHYAGKVDYKADEWLMKNMDPLNDNIATLLHQSSDKFVSELWKDVDRIVGLDQVAGMSETALPGAFKTRKGMFRTVGQLYKEQLAKLMATLRNTNPNFVRCIIPNHEKKAGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRVVFQEFRQRYEILTPNAIPKGFMDGKQACVLMIKALELDSNLYRIGQSKVFFRAGVLAHLEEERDLKITDVIIGFQACCRGYLARKAFAKRQQQLTAMKVLQRNCAAYLKLRNWQWWRLFTKVKPLLQVSRQEEEMMAKEEELIKVKEKQLAAENRLSEMETFQAQLMAEKMQLQEQLQAEAELCAEAEEIRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEDVIVLEDQNLKLAKEKKLLEDRMSEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSSDLHDQIAELQAQIAELKIQLSKKEEELQAALARVEEEAAQKNMALKKIRELESQITELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVTVLKKTLEDEAKTHEAQIQEMRQKHSQAIEELAEQLEQTKRVKANLEKAKQALESERAELSNEVKVLLQGKGDAEHKRKKVDAQLQELQVKFTEGERVKTELAERVNKLQVELDNVTGLLNQSDSKSIKLAKDFSALESQLQDTQELLQEETRLKLSFSTKLKQTEDEKNALKEQLEEEEEAKRNLEKQISVLQQQAVEARKKMDDGLGCLEIAEEAKKKLQKDLESLTQRYEEKIAAYDKLEKTKTRLQQELDDIAVDLDHQRQTVSNLEKKQKKFDQLLAEEKNISAKYAEERDRAEAEAREKETKALSLARALEEAIEQKAELERVNKQFRTEMEDLMSSKDDVGKSVHELEKAKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNQQAMKAQFDRDLLGRDEQNEEKRKQLIRQVREMEVELEDERKQRSIAVAARKKLELDLKDLESHIDTANKNRDEAIKQLRKLQAQMKDYMRELEDTRTSREEILAQAKENEKKLKSMEAEMIQLQEEQGNTEIINDRLKKANLQIDQMNADLNAERSNAQKNENARQQMERQNKELKLKLQEMESAVKSKYKATITALEAKIVQLEEQLDMETKERQAASKQVRRAEKKLKDILLQVDDERRNAEQFKDQADKANMRLKQLKRQLEEAEEEAQRANASRRKLQRELDDATETADAMNREVSSLKSKLRRGDLPFVVTRRLVRKGTGECSDEEVDGKAEAGDAKATE", "length": 1907, "header": "tr|A0A8V0YQW8-1|A0A8V0YQW8_CHICK Computationally mapped isoform of Myosin-9 OS=Gallus gallus OX=9031 GN=MYH9 PE=1 SV=1 CANONICAL=A0A1D5PM19-1" }, "locus": { "chromosome": "1", "start_pos": 51861968, "end_pos": 51809282, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036209.1", "url": "https://www.ensembl.org/id/ENSGALT00010036209.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021049.1", "url": "https://www.ensembl.org/id/ENSGALP00010021049.1" } ] } }, { "isoform_ac": "A0A8V0YQX3-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PM19/entry#A0A8V0YQX3-1", "sequence": { "sequence": "MAQRDADKYLYVDKNIINNPLTQADWAAKKLVWVPSEKSGFEAASLKEEVGDEAIVELAENGKKVKVNKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLKERYYSGLIYTYSGLFCVVINPYKNLPIYSEEIVEMYKGKKRHEMPPHIYAITDTAYRSMMQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSHKSKKDQGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVNGYIVGANIETYLLEKSRAIRQAKEERTFHIFYYLLSGAGEHLKTDLLLEPYNKYRFLSNGHVTIPGQQDKDMFQETMEAMRIMGIPDEEQIGLLKVISGVLQLGNIVFKKERNTDQASMPDNTAAQKVSHLLGINVTDFTRGILTPRIKVGRDYVQKAQTKEQADFAIEALAKATYERMFRWLVMRINKALDKTKRQGASFIGILDIAGFEIFELNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIDLIEKPAGPPGILALLDEECWFPKATDKSFVEKVVQEQGTHPKFQKPKQLKDKADFCIIHYAGKVDYKADEWLMKNMDPLNDNIATLLHQSSDKFVSELWKDVDRIVGLDQVAGMSETALPGAFKTRKGMFRTVGQLYKEQLAKLMATLRNTNPNFVRCIIPNHEKKAGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRVVFQEFRQRYEILTPNAIPKGFMDGKQACVLMIKALELDSNLYRIGQSKVFFRAGVLAHLEEERDLKITDVIIGFQACCRGYLARKAFAKRQQQLTAMKVLQRNCAAYLKLRNWQWWRLFTKVKPLLQVSRQEEEMMAKEEELIKVKEKQLAAENRLSEMETFQAQLMAEKMQLQEQLQAEAELCAEAEEIRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEDVIVLEDQNLKLAKEKKLLEDRMSEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSSDLHDQIAELQAQIAELKIQLSKKEEELQAALARVEEEAAQKNMALKKIRELESQITELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVTVLKKTLEDEAKTHEAQIQEMRQKHSQAIEELAEQLEQTKRVKANLEKAKQALESERAELSNEVKVLLQGKGDAEHKRKKVDAQLQELQVKFTEGERVKTELAERVNKLQVELDNVTGLLNQSDSKSIKLAKDFSALESQLQDTQELLQEETRLKLSFSTKLKQTEDEKNALKEQLEEEEEAKRNLEKQISVLQQQAVEARKKMDDGLGCLEIAEEAKKKLQKDLESLTQRYEEKIAAYDKLEKTKTRLQQELDDIAVDLDHQRQTVSNLEKKQKKFDQLLAEEKNISAKYAEERDRAEAEAREKETKALSLARALEEAIEQKAELERVNKQFRTEMEDLMSSKDDVGKSVHELEKAKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNQQAMKAQFDRDLLGRDEQNEEKRKQLIRQVREMEVELEDERKQRSIAVAARKKLELDLKDLESHIDTANKNRDEAIKQLRKLQAQMKDYMRELEDTRTSREEILAQAKENEKKLKSMEAEMIQLQEMESAVKSKYKATITALEAKIVQLEEQLDMETKERQAASKQVRRAEKKLKDILLQVDDERRNAEQFKDQADKANMRLKQLKRQLEEAEEEAQRANASRRKLQRELDDATETADAMNREVSSLKSKLRRGDLPFVVTRRLVRKGTGECSDEEVDGKAEAGDAKATE", "length": 1851, "header": "tr|A0A8V0YQX3-1|A0A8V0YQX3_CHICK Computationally mapped isoform of Myosin-9 OS=Gallus gallus OX=9031 GN=MYH9 PE=1 SV=1 CANONICAL=A0A1D5PM19-1" }, "locus": { "chromosome": "1", "start_pos": 51861968, "end_pos": 51809282, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036219.1", "url": "https://www.ensembl.org/id/ENSGALT00010036219.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021055.1", "url": "https://www.ensembl.org/id/ENSGALP00010021055.1" } ] } }, { "isoform_ac": "A0A8V0YSI4-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PM19/entry#A0A8V0YSI4-1", "sequence": { "sequence": "MAQRDADKYLYVDKNIINNPLTQADWAAKKLVWVPSEKSGFEAASLKEEVGDEAIVELAENGKKVKVNKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLKERYYSGLIYTYSGLFCVVINPYKNLPIYSEEIVEMYKGKKRHEMPPHIYAITDTAYRSMMQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSHKSKKDQGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVNGYIVGANIETYLLEKSRAIRQAKEERTFHIFYYLLSGAGEHLKTDLLLEPYNKYRFLSNGHVTIPGQQDKDMFQETMEAMRIMGIPDEEQIGLLKVISGVLQLGNIVFKKERNTDQASMPDNTAAQKVSHLLGINVTDFTRGILTPRIKVGRDYVQKAQTKEQADFAIEALAKATYERMFRWLVMRINKALDKTKRQGASFIGILDIAGFEIFELNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIDLIEKPAGPPGILALLDEECWFPKATDKSFVEKVVQEQGTHPKFQKPKQLKDKADFCIIHYAGKVDYKADEWLMKNMDPLNDNIATLLHQSSDKFVSELWKDVDRIVGLDQVAGMSETALPGAFKTRKGMFRTVGQLYKEQLAKLMATLRNTNPNFVRCIIPNHEKKAGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRVVFQEFRQRYEILTPNAIPKGFMDGKQACVLMIKALELDSNLYRIGQSKVFFRAGVLAHLEEERDLKITDVIIGFQACCRGYLARKAFAKRQQQLTAMKVLQRNCAAYLKLRNWQWWRLFTKVKPLLQVSRQEEEMMAKEEELIKVKEKQLAAENRLSEMETFQAQLMAEKMQLQEQLQAEAELCAEAEEIRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEDVIVLEDQNLKLAKEKKLLEDRMSEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSSDLHDQIAELQAALARVEEEAAQKNMALKKIRELESQITELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVTVLKKTLEDEAKTHEAQIQEMRQKHSQAIEELAEQLEQTKRVKANLEKAKQALESERAELSNEVKVLLQGKGDAEHKRKKVDAQLQELQVKFTEGERVKTELAERVNKLQVELDNVTGLLNQSDSKSIKLAKDFSALESQLQDTQELLQEETRLKLSFSTKLKQTEDEKNALKEQLEEEEEAKRNLEKQISVLQQQAVEARKKMDDGLGCLEIAEEAKKKLQKDLESLTQRYEEKIAAYDKLEKTKTRLQQELDDIAVDLDHQRQTVSNLEKKQKKFDQLLAEEKNISAKYAEERDRAEAEAREKETKALSLARALEEAIEQKAELERVNKQFRTEMEDLMSSKDDVGKSVHELEKAKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNQQAMKAQFDRDLLGRDEQNEEKRKQLIRQVREMEVELEDERKQRSIAVAARKKLELDLKDLESHIDTANKNRDEAIKQLRKLQAQMKDYMRELEDTRTSREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALAMEEKRRLEARIAQLEEELEEEQGNTEIINDRLKKANLQIDQMNADLNAERSNAQKNENARQQMERQNKELKLKLQEMESAVKSKYKATITALEAKIVQLEEQLDMETKERQAASKQVRRAEKKLKDILLQVDDERRNAEQFKDQADKANMRLKQLKRQLEEAEEEAQRANASRRKLQRELDDATETADAMNREVSSLKSKLRRGDLPFVVTRRLVRKGTGECSDEEVDGKAEAGDAKATE", "length": 1942, "header": "tr|A0A8V0YSI4-1|A0A1D5PM19_CHICK Computationally mapped isoform of Myosin-9 OS=Gallus gallus OX=9031 GN=MYH9 PE=1 SV=1 CANONICAL=A0A1D5PM19-1" }, "locus": { "chromosome": "1", "start_pos": 51861968, "end_pos": 51809282, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036199.1", "url": "https://www.ensembl.org/id/ENSGALT00010036199.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021040.1", "url": "https://www.ensembl.org/id/ENSGALP00010021040.1" } ] } }, { "isoform_ac": "A0A8V0YSI9-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PM19/entry#A0A8V0YSI9-1", "sequence": { "sequence": "MAQRDADKYLYVDKNIINNPLTQADWAAKKLVWVPSEKSGFEAASLKEEVGDEAIVELAENGKKVKVNKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLKERYYSGLIYTYSGLFCVVINPYKNLPIYSEEIVEMYKGKKRHEMPPHIYAITDTAYRSMMQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSHKSKKDQGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVNGYIVGANIETYLLEKSRAIRQAKEERTFHIFYYLLSGAGEHLKTDLLLEPYNKYRFLSNGHVTIPGQQDKDMFQETMEAMRIMGIPDEEQIGLLKVISGVLQLGNIVFKKERNTDQASMPDNTAAQKVSHLLGINVTDFTRGILTPRIKVGRDYVQKAQTKEQADFAIEALAKATYERMFRWLVMRINKALDKTKRQGASFIGILDIAGFEIFELNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIDLIEKPAGPPGILALLDEECWFPKATDKSFVEKVVQEQGTHPKFQKPKQLKDKADFCIIHYAGKVDYKADEWLMKNMDPLNDNIATLLHQSSDKFVSELWKDVDRIVGLDQVAGMSETALPGAFKTRKGMFRTVGQLYKEQLAKLMATLRNTNPNFVRCIIPNHEKKAGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRVVFQEFRQRYEILTPNAIPKGFMDGKQACVLMIKALELDSNLYRIGQSKVFFRAGVLAHLEEERDLKITDVIIGFQACCRGYLARKAFAKRQQQLTAMKVLQRNCAAYLKLRNWQWWRLFTKVKPLLQVSRQEEEMMAKEEELIKVKEKQLAAENRLSEMETFQAQLMAEKMQLQEQLQAEAELCAEAEEIRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEDVIVLEDQNLKLAKEKKLLEDRMSEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSSDLHDQIAELQAQIAELKIQLSKKEEELQAALARVEEEAAQKNMALKKIRELESQITELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVTVLKKTLEDEAKTHEAQIQEMRQKHSQAIEELAEQLEQTKRVKANLEKAKQALESERVKTELAERVNKLQVELDNVTGLLNQSDSKSIKLAKDFSALESQLQDTQELLQEETRLKLSFSTKLKQTEDEKNALKEQLEEEEEAKRNLEKQISVLQQQAVEARKKMDDGLGCLEIAEEAKKKLQKDLESLTQRYEEKIAAYDKLEKTKTRLQQELDDIAVDLDHQRQTVSNLEKKQKKFDQLLAEEKNISAKYAEERDRAEAEAREKETKALSLARALEEAIEQKAELERVNKQFRTEMEDLMSSKDDVGKSVHELEKAKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNQQAMKAQFDRDLLGRDEQNEEKRKQLIRQVREMEVELEDERKQRSIAVAARKKLELDLKDLESHIDTANKNRDEAIKQLRKLQAQMKDYMRELEDTRTSREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALAMEEKRRLEARIAQLEEELEEEQGNTEIINDRLKKANLQIDQMNADLNAERSNAQKNENARQQMERQNKELKLKLQEMESAVKSKYKATITALEAKIVQLEEQLDMETKERQAASKQVRRAEKKLKDILLQVDDERRNAEQFKDQADKANMRLKQLKRQLEEAEEEAQRANASRRKLQRELDDATETADAMNREVSSLKSKLRRGDLPFVVTRRLVRKGTGECSDEEVDGKAEAGDAKATE", "length": 1920, "header": "tr|A0A8V0YSI9-1|A0A1D5PM19_CHICK Computationally mapped isoform of Myosin-9 OS=Gallus gallus OX=9031 GN=MYH9 PE=1 SV=1 CANONICAL=A0A1D5PM19-1" }, "locus": { "chromosome": "1", "start_pos": 51861968, "end_pos": 51809282, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036208.1", "url": "https://www.ensembl.org/id/ENSGALT00010036208.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021048.1", "url": "https://www.ensembl.org/id/ENSGALP00010021048.1" } ] } }, { "isoform_ac": "A0A8V0YXK6-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PM19/entry#A0A8V0YXK6-1", "sequence": { "sequence": "MAQRDADKYLYVDKNIINNPLTQADWAAKKLVWVPSEKSGFEAASLKEEVGDEAIVELAENGKKVKVNKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLKERYYSGLIYTYSGLFCVVINPYKNLPIYSEEIVEMYKGKKRHEMPPHIYAITDTAYRSMMQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSHKSKKDQGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVNGYIVGANIETYLLEKSRAIRQAKEERTFHIFYYLLSGAGEHLKTDLLLEPYNKYRFLSNGHVTIPGQQDKDMFQETMEAMRIMGIPDEEQIGLLKVISGVLQLGNIVFKKERNTDQASMPDNTAAQKVSHLLGINVTDFTRGILTPRIKVGRDYVQKAQTKEQADFAIEALAKATYERMFRWLVMRINKALDKTKRQGASFIGILDIAGFEIFELNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIDLIEKPAGPPGILALLDEECWFPKATDKSFVEKVVQEQGTHPKFQKPKQLKDKADFCIIHYAGKVDYKADEWLMKNMDPLNDNIATLLHQSSDKFVSELWKDVDRIVGLDQVAGMSETALPGAFKTRKGMFRTVGQLYKEQLAKLMATLRNTNPNFVRCIIPNHEKKAGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRVVFQEFRQRYEILTPNAIPKGFMDGKQACVLMIKALELDSNLYRIGQSKVFFRAGVLAHLEEERDLKITDVIIGFQACCRGYLARKAFAKRQQQLTAMKVLQRNCAAYLKLRNWQWWRLFTKVKPLLQVSRQEEEMMAKEEELIKVKEKQLAAENRLSEMETFQAQLMAEKMQLQEQLQAEAELCAEAEEIRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEDVIVLEDQNLKLAKEKKLLEDRMSEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSSDLHDQIAELQAQIAELKIQLSKKEEELQAALARVEEEAAQKNMALKKIRELESQITELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVTVLKKTLEDEAKTHEAQIQEMRQKHSQAIEELAEQLEQTKRVKANLEKAKQALESERAELSNEVKVLLQGKGDAEHKRKKVDAQLQELQVKFTEGERVKTELAERVNKLQVELDNVTGLLNQSDSKSIKLAKDFSALESQLQDTQELLQEETRLKLSFSTKLKQTEDEKNALKEQLEEEEEAKRNLEKQISVLQQQAVEARKKMDDGLGCLEIAEEAKKKLQKDLESLTQRYEEKIAAYDKLEKTKTRLQQELDDIAVDLDHQRQTVSNLEKKQKKFDQLLAEEKNISAKYAEERDRAEAEAREKETKALSLARALEEAIEQKAELERVNKQFRTEMEDLMSSKDDVGKSVHELEKAKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNQQAMKAQFDRDLLGRDEQNEEKRKQLIRQVREMEVELEDERKQRSIAVAARKKLELDLKDLESHIDTANKNRDEAIKQLRKLQAQMKDYMRELEDTRTSREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAASKQVRRAEKKLKDILLQVDDERRNAEQFKDQADKANMRLKQLKRQLEEAEEEAQRANASRRKLQRELDDATETADAMNREVSSLKSKLRRGDLPFVVTRRLVRKGTGECSDEEVDGKAEAGDAKATE", "length": 1827, "header": "tr|A0A8V0YXK6-1|A0A1D5PM19_CHICK Computationally mapped isoform of Myosin-9 OS=Gallus gallus OX=9031 GN=MYH9 PE=1 SV=1 CANONICAL=A0A1D5PM19-1" }, "locus": { "chromosome": "1", "start_pos": 51861968, "end_pos": 51809282, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036222.1", "url": "https://www.ensembl.org/id/ENSGALT00010036222.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021057.1", "url": "https://www.ensembl.org/id/ENSGALP00010021057.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-5627123", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5627123", "resource": "Reactome", "description": "RHO GTPases activate PAKs" } ], "orthologs": [ { "uniprot_canonical_ac": "F1MQ37-1", "protein_name": "Myosin-9", "gene_name": "MYH9", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAQQAADKYLYVDKNFINNPLAQADWAAKKLVWVPSDKSGFEPASLKEEMGEEAIVELVENGKKVKVNKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLKERYYSGLIYTYSGLFCVVINPYKNLPIYSEEIVEMYKGKKRHEMPPHIYAITDTAYRSMMQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSHKSKKDQGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVNGYIVGANIETYLLEKSRAIRQAKEERTFHIFYYLLSGAGEHLKSDLLLESYNKYRFLSNGHVTIPGQQDKDMFQETMEAFRIMGIPEEEQMGLLRVISGVLQLGNIVFKKERNSDQASMPDNTAAQKVSHLLGINVTDFTRGILTPRIKVGRDYVQKAQTKEQADFAIEALAKATYERMFRWLVLRINKALDKTKRQGASFIGILDIAGFEIFDLNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIDLIEKPAGPPGILALLDEECWFPKATDKSFVEKVMQEQGTHPKFQKPKQLKDKADFCIIHYAGKVDYKADEWLMKNMDPLNDNIATLLHQSSDKFVSELWKDVDRIIGLDQVAGMSETAMPGAFKTRKGMFRTVGQLYKEQLAKLMATLRNTNPNFVRCIIPNHEKKAGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRVVFQEFRQRYEILTPNSIPKGFMDGKQACVLMIKALELDSNLYRIGQSKVFFRAGVLAHLEEERDLKITDVIIGFQACCRGYLARKAFAKRQQQLTAMKVLQRNCAAYLKLRNWQWWRLFTKVKPLLQVSRQEEEMMAKEEELVKVREKQLAAENRLSEMETLQSQLLAEKLQLQEQLQAETELCAEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEDQIIMEDQNCKLAKEKKLLEDRIAEFTTNLMEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLNDQIAELQAQIAELKMQLAKKEEELQAALARVEEETTQKNMALKKIRELESQISELQEDLESERAARNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKRTLEDEARIHEAQIQDMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLQQGKADTEHKRKKVEAQLQELQVKFTEGERVRTELADKVSKLQVELDNVTGLLTQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSLKEQLEEEEEAKRNLEKQISTLHAQVTDMRKKMDDSVGCLETAEEAKRKLQKDLEGLSQCYEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSVSNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVKQVREMEAELEDERKQRSIAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKVQAQMKDYMRELDDTRASREEILAQSKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTELVNDRLKKANLQIDQLNTDLNLERSHTQKNENARQQLERQNKELKVKLQEMEGTVKSKFKASIAALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQRELEDATETADAMNREVSSLKNKLRRGDLPFVVPRRMARKGASDCSDDEMDGKADGAEAKAAEARAAE", "length": 1965 }, "evidence": [ { "id": "A0A1D5PM19", "url": "https://omabrowser.org/oma/group/A0A1D5PM19/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P08799-1", "protein_name": "Myosin-2 heavy chain", "gene_name": "mhcA", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNPIHDRTSDYHKYLKVKQGDSDLFKLTVSDKRYIWYNPDPKERDSYECGEIVSETSDSFTFKTVDGQDRQVKKDDANQRNPIKFDGVEDMSELSYLNEPAVFHNLRVRYNQDLIYTYSGLFLVAVNPFKRIPIYTQEMVDIFKGRRRNEVAPHIFAISDVAYRSMLDDRQNQSLLITGESGAGKTENTKKVIQYLASVAGRNQANGSGVLEQQILQANPILEAFGNAKTTRNNNSSRFGKFIEIQFNSAGFISGASIQSYLLEKSRVVFQSETERNYHIFYQLLAGATAEEKKALHLAGPESFNYLNQSGCVDIKGVSDSEEFKITRQAMDIVGFSQEEQMSIFKIIAGILHLGNIKFEKGAGEGAVLKDKTALNAASTVFGVNPSVLEKALMEPRILAGRDLVAQHLNVEKSSSSRDALVKALYGRLFLWLVKKINNVLCQERKAYFIGVLDISGFEIFKVNSFEQLCINYTNEKLQQFFNHHMFKLEQEEYLKEKINWTFIDFGLDSQATIDLIDGRQPPGILALLDEQSVFPNATDNTLITKLHSHFSKKNAKYEEPRFSKTEFGVTHYAGQVMYEIQDWLEKNKDPLQQDLELCFKDSSDNVVTKLFNDPNIASRAKKGANFITVAAQYKEQLASLMATLETTNPHFVRCIIPNNKQLPAKLEDKVVLDQLRCNGVLEGIRITRKGFPNRIIYADFVKRYYLLAPNVPRDAEDSQKATDAVLKHLNIDPEQYRFGITKIFFRAGQLARIEEAREQRISEIIKAIQAATRGWIARKVYKQAREHTVAARIIQQNLRAYIDFKSWPWWKLFSKARPLLKRRNFEKEIKEKEREILELKSNLTDSTTQKDKLEKSLKDTESNVLDLQRQLKAEKETLKAMYDSKDALEAQKRELEIRVEDMESELDEKKLALENLQNQKRSVEEKVRDLEEELQEEQKLRNTLEKLKKKYEEELEEMKRVNDGQSDTISRLEKIKDELQKEVEELTESFSEESKDKGVLEKTRVRLQSELDDLTVRLDSETKDKSELLRQKKKLEEELKQVQEALAAETAAKLAQEAANKKLQGEYTELNEKFNSEVTARSNVEKSKKTLESQLVAVNNELDEEKKNRDALEKKKKALDAMLEEMKDQLESTGGEKKSLYDLKVKQESDMEALRNQISELQSTIAKLEKIKSTLEGEVARLQGELEAEQLAKSNVEKQKKKVELDLEDKSAQLAEETAAKQALDKLKKKLEQELSEVQTQLSEANNKNVNSDSTNKHLETSFNNLKLELEAEQKAKQALEKKRLGLESELKHVNEQLEEEKKQKESNEKRKVDLEKEVSELKDQIEEEVASKKAVTEAKNKKESELDEIKRQYADVVSSRDKSVEQLKTLQAKNEELRNTAEEAEGQLDRAERSKKKAEFDLEEAVKNLEEETAKKVKAEKAMKKAETDYRSTKSELDDAKNVSSEQYVQIKRLNEELSELRSVLEEADERCNSAIKAKKTAESALESLKDEIDAANNAKAKAERKSKELEVRVAELEESLEDKSGTVNVEFIRKKDAEIDDLRARLDRETESRIKSDEDKKNTRKQFADLEAKVEEAQREVVTIDRLKKKLESDIIDLSTQLDTETKSRIKIEKSKKKLEQTLAERRAAEEGSSKAADEEIRKQVWQEVDELRAQLDSERAALNASEKKIKSLVAEVDEVKEQLEDEILAKDKLVKAKRALEVELEEVRDQLEEEEDSRSELEDSKRRLTTEVEDIKKKYDAEVEQNTKLDEAKKKLTDDVDTLKKQLEDEKKKLNESERAKKRLESENEDFLAKLDAEVKNRSRAEKDRKKYEKDLKDTKYKLNDEAATKTQTEIGAAKLEDQIDELRSKLEQEQAKATQADKSKKTLEGEIDNLRAQIEDEGKIKMRLEKEKRALEGELEELRETVEEAEDSKSEAEQSKRLVELELEDARRNLQKEIDAKEIAEDAKSNLQREIVEAKGRLEEESIARTNSDRSRKRLEAEIDALTAQVDAEQKAKNQQIKENKKIETELKEYRKKFGESEKTKTKEFLVVEKLETDYKRAKKEAADEQQQRLTVENDLRKHLSEISLLKDAIDKLQRDHDKTKRELETETASKIEMQRKMADFFGGFKA", "length": 2116 }, "evidence": [ { "id": "A0A1D5PM19", "url": "https://omabrowser.org/oma/group/A0A1D5PM19/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "P08964-1", "protein_name": "Myosin-1", "gene_name": "MYO1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MTGGQSCSSNMIVWIPDEKEVFVKGELMSTDINKNKFTGQEEQIGIVHPLDSTEVSNLVQVRISDVFPVNPSTFDKVENMSELTHLNEPSVLYNLEKRYDCDLIYTYSGLFLVAINPYHNLNLYSEDHINLYHNKHNRLSKSRLDENSHEKLPPHIFAIAEEAYENLLSEGKDQSILVTGESGAGKTENTKKILQYLASITSGSPSNIAPVSGSSIVESFEMKILQSNPILESFGNAQTVRNNNSSRFGKFIKIEFNEHGMINGAHIEWYLLEKSRIVHQNSKERNYHIFYQLLSGLDDSELKNLRLKSRNVKDYKILSNSNQDIIPGINDVENFKELLSALNIIGFSKDQIRWIFQVVAIILLIGNIEFVSDRAEQASFKNDVSAICSNLGVDEKDFQTAILRPRSKAGKEWVSQSKNSQQAKFILNALSRNLYERLFGYIVDMINKNLDHGSATLNYIGLLDIAGFEIFENNSFEQLCINYTNEKLQQFFNNHMFVLEQSEYLKENIQWDYIDYGKDLQLTIDLIESKGPPTGVLPLLDEEAVLPKSTDESFYSKLISTWDQNSSKFKRSRLKNGFILKHYAGDVEYTVEGWLSKNKDPLNDNLLSLLSSSQNDIISKLFQPEGEKSSSAGVEANISNQEVKKSARTSTFKTTSSRHREQQITLLNQLASTHPHFVRCIIPNNVKKVKTFNRRLILDQLRCNGVLEGIRLAREGYPNRIAFQEFFQRYRILYPENSTTTTFSSKLKASTKQNCEFLLTSLQLDTKVYKIGNTKLFFKAGVLADLEKQKDVKLNNIMIKLTATIRGYTVRKEITYHLQKLKKTRVIGNTFRLYNRLVKEDPWFNLFIRIKPLLTSSNDMTRTKKFNEQINKLKNDLQEMESKKKFLEEKNQKTVNELENTQDLLNQEKENLRKNESLLNRVKTSSETLQKQFDDLVSEKDEISREKLEVAQNLEEAHQKIQGLQETIREREATLEKLHSKNNELIKQISDLNCDISKEQSSQSLIKESKLKLENEIKRLKDVINSKEEEIKSFNDKLSSSEEDLDIKLVTLEKNCNIAMSRLQSLVTENSDLRSKNENFKKEKAALNNQLKNKESELLKMKEKIDNHKKELATFSKQRDDAVSEHGKITAELKETRIQLTEYKSNYQKIKEEYSNFQRETKEQEQKKRNSLVESLNDSKIKELEARLSQEISLNQYLNKRISGNSVETNISSTRRSTSYSDDPLDKEDIIKKYYDLQLAFTEITRNLENEIEEKKNLISRLRFTETRLASSSFEDQKIKAQMKKLKKLIQDMDPSIPLDSILNEPLDNCPDKESDINKLMLEVDYLKRQLDIETRAHYDAENAISALHSKFRKIQGESSLSSSDIYKLKFEASEERVKSLEDKLKTMPLRDRTNLPVGDIIKNRDSISKYEEEIRYYKLENYKLQEILNESNGKLSQLTLDLRQSKSKEALLSEQLDRLQKDLESTERQKELLSSTIKQQKQQFENCMDDLQGNELRLREHIHALKQAEEDVKNMASIIEKLKTQNKQKEKLIWEREMERNDSDMQLQETLLELKRVQDVKKILSDDLAHLKERLSAVEDRSQYTDEINRLKEELNCSLKAETNLKKEFATLKYKLETSTNDSEAKISDLLKQLDHYTKVVEMLNNEKDAISLAEKELYQKYEALNTECESLKGKIVSLTKIKQELESDLNQKTDALQISNAALSSSTQKNKEITEKIKYLEETLQLQMEQNSRNGELVKTLQASCNGYKDKFDDEKQKNIDLYEENQTLQKLNTDLQLQLKNLHERLSDTTEKNAWLSKIHELENMVSLETDLKYEEMKKNKSLERAVEELQTKNSQQTDVIELANKNRSEFEEATLKYEAQISDLEKYISQQELEMKKSIRDNSSYRDKVQEMAQEIEFWKSRYESTMIGSKNIDSNNAQSKIFS", "length": 1928 }, "evidence": [ { "id": "A0A1D5PM19", "url": "https://omabrowser.org/oma/group/A0A1D5PM19/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P35579-1", "protein_name": "Myosin-9", "gene_name": "MYH9", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAQQAADKYLYVDKNFINNPLAQADWAAKKLVWVPSDKSGFEPASLKEEVGEEAIVELVENGKKVKVNKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLKERYYSGLIYTYSGLFCVVINPYKNLPIYSEEIVEMYKGKKRHEMPPHIYAITDTAYRSMMQDREDQSILCTGESGAGKTENTKKVIQYLAYVASSHKSKKDQGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVNGYIVGANIETYLLEKSRAIRQAKEERTFHIFYYLLSGAGEHLKTDLLLEPYNKYRFLSNGHVTIPGQQDKDMFQETMEAMRIMGIPEEEQMGLLRVISGVLQLGNIVFKKERNTDQASMPDNTAAQKVSHLLGINVTDFTRGILTPRIKVGRDYVQKAQTKEQADFAIEALAKATYERMFRWLVLRINKALDKTKRQGASFIGILDIAGFEIFDLNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIDLIEKPAGPPGILALLDEECWFPKATDKSFVEKVMQEQGTHPKFQKPKQLKDKADFCIIHYAGKVDYKADEWLMKNMDPLNDNIATLLHQSSDKFVSELWKDVDRIIGLDQVAGMSETALPGAFKTRKGMFRTVGQLYKEQLAKLMATLRNTNPNFVRCIIPNHEKKAGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRVVFQEFRQRYEILTPNSIPKGFMDGKQACVLMIKALELDSNLYRIGQSKVFFRAGVLAHLEEERDLKITDVIIGFQACCRGYLARKAFAKRQQQLTAMKVLQRNCAAYLKLRNWQWWRLFTKVKPLLQVSRQEEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCAEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQRELEDATETADAMNREVSSLKNKLRRGDLPFVVPRRMARKGAGDGSDEEVDGKADGAEAKPAE", "length": 1960 }, "evidence": [ { "id": "A0A1D5PM19", "url": "https://omabrowser.org/oma/group/A0A1D5PM19/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q62812-1", "protein_name": "Myosin-9", "gene_name": "Myh9", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAQQAADKYLYVDKNFINNPLAQADCGAKKLVWVPSTKNGFEPASLKEEVGEEAIVELVENGKKVKVNKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLKERYYSGLIYTYSGLFCVVINPYKNLPIYSEEIVDMYKGKKRHEMPPHIYAITDTAYRSMMQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSHKSKKDQGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVNGYIVGANIETYLLEKSRAIRQAKEERTFHIFYYLLSGAGEHLKTDLLLEPYNKYRFLSNGHVTIPGQQDKDMFQETMEAMRIMGIPEDEQMGLLRVISGVLQLGNIVFKKERNTDQASMPDNTAAQKVSHLLGINVTDFTRGILTPRIKVGRDYVQKAQTKEQADFAIEALAKATYERMFRWLVLRINKALDKTKRQGASFIGILDIAGFEIFDLNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIDLIEKPAGPPGILALLDEECWFPKATDKSFVEKVVQEQGTHPKFQKPKQLKDKADFCIIHYAGKVDYKADEWLMKNMDPLNDNIATLLHQSSDKFVSELWKDVDRIIGLDQVAGMSETALPGAFKTRKGMFRTVGQLYKEQLAKLMATLRNTNPNFVCCIIPNHEKKAGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRVVFQEFRQRYEILTPNSIPKGFMDGKQACVLMIKALELDSNLYRIGQSKVFFRSGVLAHLEEERDLKITDVIIGFQACCRGYLARKAFAKRQQQLTAMKVLQRNCAAYLRLRNWQWWRLFTKVKPLLNSIRHEDELLAKEAELTKVREKHLAAENRLTEMETMQSQLMAEKLQLQEQLQAKTELCAEAEELRARLTAKKQELEEICHDLEARVEEEEERCQYLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEDQIIMEDQNCKLAKEKKLLEDRVAEFTTDLMEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELETQISELQEDLESERACRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVSILKKTLEDEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKATLEKAKQTLENERGELANEVKALLQGKGDSEHKRKKVEAQLQELQVKFSEGERVRTELADKVSKLQVELDSVTGLLNQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQMEDEKNSFREQLEEEEEEAKRNLEKQIATLHAQVTDMKKKMEDGVGCLETAEEAKRRLQKDLEGLSQRLEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSVSNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSNRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSIAMAARKKLEMDLKDLEAHIDTANKNREEAIKQLRKLQAQMKDCMRDVDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEALIALLEEELEEEQGNTELINDRLKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKAKLQEMESAVKSKYKASIAALEAKIAQLEEQLDNETKERQAASKQVRRAEKKLKDVLLQVEDERRNAEQFKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQRELEDATETADAMNREVSSLKNKLRRGDMPFVVTRRIVRKGTGDCSDEEVDGKADGADAKATE", "length": 1961 }, "evidence": [ { "id": "A0A1D5PM19", "url": "https://omabrowser.org/oma/group/A0A1D5PM19/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8VDD5-1", "protein_name": "Myosin-9", "gene_name": "Myh9", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAQQAADKYLYVDKNFINNPLAQADWAAKKLVWVPSSKNGFEPASLKEEVGEEAIVELVENGKKVKVNKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLKERYYSGLIYTYSGLFCVVINPYKNLPIYSEEIVEMYKGKKRHEMPPHIYAITDTAYRSMMQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSHKSKKDQGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVNGYIVGANIETYLLEKSRAIRQAKEERTFHIFYYLLSGAGEHLKTDLLLEPYNKYRFLSNGHVTIPGQQDKDMFQETMEAMRIMGIPEDEQMGLLRVISGVLQLGNIAFKKERNTDQASMPDNTAAQKVSHLLGINVTDFTRGILTPRIKVGRDYVQKAQTKEQADFAIEALAKATYERMFRWLVLRINKALDKTKRQGASFIGILDIAGFEIFDLNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIDLIEKPAGPPGILALLDEECWFPKATDKSFVEKVVQEQGTHPKFQKPKQLKDKADFCIIHYAGKVDYKADEWLMKNMDPLNDNIATLLHQSSDKFVSELWKDVDRIIGLDQVAGMSETALPGAFKTRKGMFRTVGQLYKEQLAKLMATLRNTNPNFVRCIIPNHEKKAGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRVVFQEFRQRYEILTPNSIPKGFMDGKQACVLMIKALELDSNLYRIGQSKVFFRAGVLAHLEEERDLKITDVIIGFQACCRGYLARKAFAKRQQQLTAMKVLQRNCAAYLRLRNWQWWRLFTKVKPLLNSIRHEDELLAKEAELTKVREKHLAAENRLTEMETMQSQLMAEKLQLQEQLQAETELCAEAEELRARLTAKKQELEEICHDLEARVEEEEERCQYLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEDQIIMEDQNCKLAKEKKLLEDRVAEFTTNLMEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELETQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVSILKKTLEDEAKTHEAQIQEMRQKHSQAVEELADQLEQTKRVKATLEKAKQTLENERGELANEVKALLQGKGDSEHKRKKVEAQLQELQVKFSEGERVRTELADKVTKLQVELDSVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQMEDEKNSFREQLEEEEEAKRNLEKQIATLHAQVTDMKKKMEDGVGCLETAEEAKRRLQKDLEGLSQRLEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSVSNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAMAARKKLEMDLKDLEAHIDTANKNREEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKAKLQEMESAVKSKYKASIAALEAKIAQLEEQLDNETKERQAASKQVRRTEKKLKDVLLQVEDERRNAEQFKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQRELEDATETADAMNREVSSLKNKLRRGDLPFVVTRRIVRKGTGDCSDEEVDGKADGADAKAAE", "length": 1960 }, "evidence": [ { "id": "A0A1D5PM19", "url": "https://omabrowser.org/oma/group/A0A1D5PM19/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q99323-3", "protein_name": "Myosin heavy chain, non-muscle", "gene_name": "zip", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MKSAWLALKSKSALHPKSEYPVSNIHYPKAANYRQTRNYLEIAAKMSEEVDRNDPELKYLSVERNQFNDPATQAEWTQKRLVWVPHENQGFVAASIKREHGDEVEVELAETGKRVMILRDDIQKMNPPKFDKVEDMAELTCLNEASVLHNIKDRYYSGLIYTYSGLFCVVVNPYKKLPIYTEKIMERYKGIKRHEVPPHVFAITDSAYRNMLGDREDQSILCTGESGAGKTENTKKVIQFLAYVAASKPKGSGAVPHPAVLINFSVNTNKYIKVKIMAQNQNQTIEVVNGLKMVEVNSNCQEGELEQQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDASGFISGANIETYLLEKSRAIRQAKDERTFHIFYQLLAGATPEQREKFILDDVKSYAFLSNGSLPVPGVDDYAEFQATVKSMNIMGMTSEDFNSIFRIVSAVLLFGSMKFRQERNNDQATLPDNTVAQKIAHLLGLSVTDMTRAFLTPRIKVGRDFVTKAQTKEQVEFAVEAIAKACYERMFKWLVNRINRSLDRTKRQGASFIGILDMAGFEIFELNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWKFIDFGLDLQPTIDLIDKPGGIMALLDEECWFPKATDKTFVDKLVSAHSMHPKFMKTDFRGVADFAIVHYAGRVDYSAAKWLMKNMDPLNENIVSLLQGSQDPFVVNIWKDAEIVGMAQQALTDTQFGARTRKGMFRTVSHLYKEQLAKLMDTLRNTNPNFVRCIIPNHEKRAGKIDAPLVLDQLRCNGVLEGIRICRQGFPNRIPFQEFRQRYELLTPNVIPKGFMDGKKACEKMIQALELDSNLYRVGQSKIFFRAGVLAHLEEERDFKISDLIVNFQAFCRGFLARRNYQKRLQQLNAIRIIQRNCAAYLKLRNWQWWRLYTKVKPLLEVTKQEEKLVQKEDELKQVREKLDTLAKNTQEYERKYQQALVEKTTLAEQLQAEIELCAEAEESRSRLMARKQELEDMMQELETRIEEEEERVLALGGEKKKLELNIQDLEEQLEEEEAARQKLQLEKVQLDAKIKKYEEDLALTDDQNQKLLKEKKLLEERANDLSQTLAEEEEKAKHLAKLKAKHEATISELEERLHKDQQQRQESDRSKRKIETEVADLKEQLNERRVQVDEMQAQLAKREEELTQTLLRIDEESATKATAQKAQRELESQLAEIQEDLEAEKAARAKAEKVRRDLSEELEALKNELLDSLDTTAAQQELRSKREQELATLKKSLEEETVNHEGVLADMRHKHSQELNSINDQLENLRKAKTVLEKAKGTLEAENADLATELRSVNSSRQENDRRRKQAESQIAELQVKLAEIERARSELQEKCTKLQQEAENITNQLEEAELKASAAVKSASNMESQLTEAQQLLEEETRQKLGLSSKLRQIESEKEALQEQLEEDDEAKRNYERKLAEVTTQMQEIKKKAEEDADLAKELEEGKKRLNKDIEALERQVKELIAQNDRLDKSKKKIQSELEDATIELEAQRTKVLELEKKQKNFDKILAEEKAISEQIAQERDTAEREAREKETKVLSVSRELDEAFDKIEDLENKRKTLQNELDDLANTQGTADKNVHELEKAKRALESQLAELKAQNEELEDDLQLTEDAKLRLEVNMQALRSQFERDLLAKEEGAEEKRRGLVKQLRDLETELDEERKQRTAAVASKKKLEGDLKEIETTMEMHNKVKEDALKHAKKLQAQVKDALRDAEEAKAAKEELQALSKEAERKVKALEAEVLQLTEDLASSERARRAAETERDELAEEIANNANKGSLMIDEKRRLEARIATLEEELEEEQSNSEVLLDRSRKAQLQIEQLTTELANEKSNSQKNENGRALLERQNKELKAKLAEIETAQRTKVKATIATLEAKIANLEEQLENEGKERLLQQKANRKMDKKIKELTMNIEDERRHVDQHKEQMDKLNSRIKLLKRNLDETEEELQKEKTQKRKYQRECEDMIESQEAMNREINSLKTKLRRTGGIGLSSSRLTGTPSSKRAGGGGGGDDSSVQDESLDGEDSAN", "length": 2056 }, "evidence": [ { "id": "A0A1D5PM19", "url": "https://omabrowser.org/oma/group/A0A1D5PM19/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 21, "go_terms": [ { "name": "plasma membrane repair", "id": "GO:0001778", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001778", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PM19", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PM19" } ], "pmid": "" }, { "name": "positive regulation of protein processing in phagocytic vesicle", "id": "GO:1903923", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903923", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PM19", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PM19" } ], "pmid": "" }, { "name": "angiogenesis", "id": "GO:0001525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001525", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PM19", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PM19" } ], "pmid": "" }, { "name": "membrane protein ectodomain proteolysis", "id": "GO:0006509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006509", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PM19", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PM19" } ], "pmid": "" }, { "name": "phagocytosis, engulfment", "id": "GO:0006911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006911", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PM19", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PM19" } ], "pmid": "" }, { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PM19", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PM19" } ], "pmid": "" }, { "name": "actin filament-based movement", "id": "GO:0030048", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030048", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PM19", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PM19" } ], "pmid": "" }, { "name": "actomyosin structure organization", "id": "GO:0031032", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031032", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PM19", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PM19" } ], "pmid": "" }, { "name": "regulation of cell shape", "id": "GO:0008360", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008360", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PM19", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PM19" } ], "pmid": "" }, { "name": "cytokinetic process", "id": "GO:0032506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032506", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PM19", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PM19" } ], "pmid": "" }, { "name": "blood vessel endothelial cell migration", "id": "GO:0043534", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043534", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PM19", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PM19" } ], "pmid": "" }, { "name": "platelet formation", "id": "GO:0030220", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030220", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PM19", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PM19" } ], "pmid": "" }, { "name": "lysosome localization", "id": "GO:0032418", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032418", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PM19", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PM19" } ], "pmid": "" }, { "name": "supramolecular fiber organization", "id": "GO:0097435", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097435", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PM19", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PM19" } ], "pmid": "" }, { "name": "monocyte differentiation", "id": "GO:0030224", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030224", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PM19", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PM19" } ], "pmid": "" }, { "name": "negative regulation of actin filament severing", "id": "GO:1903919", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903919", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PM19", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PM19" } ], "pmid": "" }, { "name": "regulation of plasma membrane repair", "id": "GO:1905684", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905684", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PM19", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PM19" } ], "pmid": "" }, { "name": "cortical granule exocytosis", "id": "GO:0060471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060471", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PM19", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PM19" } ], "pmid": "" }, { "name": "cytoskeleton organization", "id": "GO:0007010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007010", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PM19", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PM19" } ], "pmid": "" }, { "name": "actin filament-based process", "id": "GO:0030029", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030029", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PM19", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PM19" } ], "pmid": "" }, { "name": "actin cytoskeleton organization", "id": "GO:0030036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030036", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PM19", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PM19" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 11, "go_terms": [ { "name": "integrin binding", "id": "GO:0005178", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005178", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PM19", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PM19" } ], "pmid": "" }, { "name": "calmodulin binding", "id": "GO:0005516", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005516", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PM19", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PM19" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PM19", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PM19" } ], "pmid": "" }, { "name": "protein domain specific binding", "id": "GO:0019904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019904", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PM19", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PM19" } ], "pmid": "" }, { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PM19", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PM19" } ], "pmid": "" }, { "name": "actin filament binding", "id": "GO:0051015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051015", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PM19", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PM19" } ], "pmid": "" }, { "name": "ADP binding", "id": "GO:0043531", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043531", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PM19", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PM19" } ], "pmid": "" }, { "name": "virus receptor activity", "id": "GO:0001618", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001618", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PM19", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PM19" } ], "pmid": "" }, { "name": "protein-membrane adaptor activity", "id": "GO:0043495", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043495", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PM19", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PM19" } ], "pmid": "" }, { "name": "microfilament motor activity", "id": "GO:0000146", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000146", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PM19", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PM19" } ], "pmid": "" }, { "name": "cytoskeletal motor activity", "id": "GO:0003774", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003774", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PM19", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PM19" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 23, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PM19", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PM19" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PM19", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PM19" } ], "pmid": "" }, { "name": "spindle", "id": "GO:0005819", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005819", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PM19", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PM19" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PM19", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PM19" } ], "pmid": "" }, { "name": "brush border", "id": "GO:0005903", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005903", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PM19", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PM19" } ], "pmid": "" }, { "name": "adherens junction", "id": "GO:0005912", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005912", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PM19", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PM19" } ], "pmid": "" }, { "name": "focal adhesion", "id": "GO:0005925", "url": 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{ "uniprot_canonical_ac": "A0A3Q2TTF7-1", "uniprot_ac": "A0A3Q2TTF7", "uniprot_id": "A0A3Q2TTF7_CHICK", "mass": { "chemical_mass": 55918.0, "monoisotopic_mass": 55918.0 }, "refseq": { "ac": "XP_415106", "name": "scavenger receptor class B member 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_415106" }, "gene_names": [ { "name": "SCARB1", "type": "recommended", "evidence": [ { "id": "A0A3Q2TTF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TTF7" } ] }, { "name": "SCARB1", "type": "synonym", "evidence": [ { "id": "XP_415106", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_415106" } ] } ], "protein_names": [ { "name": "Scavenger receptor class B member 1", "type": "recommended", "evidence": [ { "id": "A0A3Q2TTF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TTF7/entry#names_and_taxonomy" } ] }, { "name": "SR-BI", "type": "synonym", "evidence": [ { "id": "A0A3Q2TTF7", "database": 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This record is derived from a genomic sequence (NC_052546.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Nov 16, 2006 this sequence version replaced XP_415106.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_415106", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_415106" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TTF7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TTF7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SCARB1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TTF7", "locus": { "chromosome": "15", "start_pos": 4547032, "end_pos": 4530763, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021011", "url": "https://www.ensembl.org/id/ENSGALG00010021011" } ] } } ], "crossref": [ { "id": "A0A3Q2TTF7", "url": "https://alphafold.ebi.ac.uk/entry/A0A3Q2TTF7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000046226", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000046226", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "416814", "url": "https://www.ncbi.nlm.nih.gov/gene/416814", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002159", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002159", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005428", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005428", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416814", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416814", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DENYWIN", "url": "https://omabrowser.org/oma/group/DENYWIN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PMI6", "url": "https://www.orthodb.org/?gene=A0A1D5PMI6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2TTF7", "url": "https://www.orthodb.org/?gene=A0A3Q2TTF7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZGQ0", "url": "https://www.orthodb.org/?gene=A0A8V0ZGQ0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZGQ6", "url": "https://www.orthodb.org/?gene=A0A8V0ZGQ6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NAN9", "url": "https://www.orthodb.org/?gene=F1NAN9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11923", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11923", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11923:SF110", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11923:SF110", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01130", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01130", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-3000471", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3000471", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-8964011", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8964011", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_415106", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_415106", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PMI6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMI6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PMI6-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMI6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2TTF7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TTF7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2TTF7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TTF7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZGQ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGQ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZGQ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGQ0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZGQ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGQ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZGQ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGQ6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NAN9", "url": "https://www.uniprot.org/uniprotkb/F1NAN9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NAN9-1", "url": "https://www.uniprot.org/uniprotkb/F1NAN9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVAAGRRVAVGLGAVGAVCLLLGGCLLLAGPAIVKEQVLKNVRIDPSSISFNMWRDIPVPFYLTVNLFEVQNPQEVLQGAKPKVNQRGPYVYREFKYKTNITFHDNDTVSYLEYRQLFFRPDLSNGTEDEYIVMPNILMLGAAVMMENLPSFVKLLLSGALAGLKQEAFINRTVGEILWGYEDPLLDTINALVPGLIPYKGKFGIFIEFNNTNSGLFTVNTGMKNISQVHMVDSWNGLKKVNYWRTNECNMINGTAGEMWPPYMSPTSLEFYSPDACRSMTLVYEQSGKFKGVPTYRFVAPKTLFANGTDYPPNEGFCPCRQSGIQNVSSCRLNAPMFISHPHFYNADPSLVDAVEGLHPSREEHALFLDVHPVTGIPMNCSIKLQLNQYMKQVSGILQTGKIQPVVMPLLWFAESGYIDGSVLSQFYTNLVLIPSILDYLQYIFLGLSVPLIISAALVMMSQKSSKEKHPHDPTTQSPPPQPSETTPLLQDTGTQSQDTAEA", "length": 503, "header": "tr|A0A3Q2TTF7-1|A0A3Q2TTF7_CHICK Isoform 1 of Scavenger receptor class B member 1 OS=Gallus gallus OX=9031 GN=SCARB1 PE=1 SV=1 CANONICAL=A0A3Q2TTF7-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PMI6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TTF7/entry#A0A1D5PMI6-1", "sequence": { "sequence": "MEGKQWSDVQSLAETPGAVFGANVRIDPSSISFNMWRDIPVPFYLTVNLFEVQNPQEVLQGAKPKVNQRGPYVYREFKYKTNITFHDNDTVSYLEYRQLFFRPDLSNGTEDEYIVMPNILMLGAAVMMENLPSFVKLLLSGALAGLKQEAFINRTVGEILWGYEDPLLDTINALVPGLIPYKGKFGIFIEFNNTNSGLFTVNTGMKNISQVHMVDSWNGLKKVNYWRTNECNMINGTAGEMWPPYMSPTSLEFYSPDACRSMTLVYEQSGKFKGVPTYRFVAPKTLFANGTDYPPNEGFCPCRQSGIQNVSSCRLNAPMFISHPHFYNADPSLVDAVEGLHPSREEHALFLDVHPVTGIPMNCSIKLQLNQYMKQVSGILQTGKIQPVVMPLLWFAESGYIDGSVLSQFYTNLVLIPSILDYLQYIFLGLSVPLIISAALVMMSQKSSKEKHPHDPTTQSPPPQPSETTPLLQDTGTQSQDTAEA", "length": 485, "header": "tr|A0A1D5PMI6-1|A0A1D5PMI6_CHICK Computationally mapped isoform of Scavenger receptor class B member 1 OS=Gallus gallus OX=9031 GN=SCARB1 PE=1 SV=3 CANONICAL=A0A3Q2TTF7-1" }, "locus": { "chromosome": "15", "start_pos": 4546733, "end_pos": 4532233, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050820.1", "url": "https://www.ensembl.org/id/ENSGALT00010050820.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030011.1", "url": "https://www.ensembl.org/id/ENSGALP00010030011.1" } ] } }, { "isoform_ac": "A0A3Q2TTF7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TTF7/entry#A0A3Q2TTF7-1", "sequence": { "sequence": "MVAAGRRVAVGLGAVGAVCLLLGGCLLLAGPAIVKEQVLKNVRIDPSSISFNMWRDIPVPFYLTVNLFEVQNPQEVLQGAKPKVNQRGPYVYREFKYKTNITFHDNDTVSYLEYRQLFFRPDLSNGTEDEYIVMPNILMLGAAVMMENLPSFVKLLLSGALAGLKQEAFINRTVGEILWGYEDPLLDTINALVPGLIPYKGKFGIFIEFNNTNSGLFTVNTGMKNISQVHMVDSWNGLKKVNYWRTNECNMINGTAGEMWPPYMSPTSLEFYSPDACRSMTLVYEQSGKFKGVPTYRFVAPKTLFANGTDYPPNEGFCPCRQSGIQNVSSCRLNAPMFISHPHFYNADPSLVDAVEGLHPSREEHALFLDVHPVTGIPMNCSIKLQLNQYMKQVSGILQTGKIQPVVMPLLWFAESGYIDGSVLSQFYTNLVLIPSILDYLQYIFLGLSVPLIISAALVMMSQKSSKEKHPHDPTTQSPPPQPSETTPLLQDTGTQSQDTAEA", "length": 503, "header": "tr|A0A3Q2TTF7-1|A0A3Q2TTF7_CHICK Isoform 1 of Scavenger receptor class B member 1 OS=Gallus gallus OX=9031 GN=SCARB1 PE=1 SV=1 CANONICAL=A0A3Q2TTF7-1" }, "locus": { "chromosome": "15", "start_pos": 4546733, "end_pos": 4530840, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050825.1", "url": "https://www.ensembl.org/id/ENSGALT00010050825.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030016.1", "url": "https://www.ensembl.org/id/ENSGALP00010030016.1" } ] } }, { "isoform_ac": "A0A8V0ZGQ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TTF7/entry#A0A8V0ZGQ0-1", "sequence": { "sequence": "MVAAGRRVAVGLGAVGAVCLLLGGCLLLAGPAIVKEQVLKNVRIDPSSISFNMWRDIPVPFYLTVNLFEVQNPQEVLQGAKPKVNQRGPYVYREFKYKTNITFHDNDTVSYLEYRQLFFRPDLSNGTEDEYIVMPNILMLGAAVMMENLPSFVKLLLSGALAGLKQEAFINRTVGEILWGYEDPLLDTINALVPGLIPYKGKFGIFIEFNNTNSGLFTVNTGMKNISQVHMVDSWNGLKKVNYWRTNECNMINGTAGEMWPPYMSPTSLEFYSPDACRSMTLVYEQSGKFKGVPTYRFVAPKTLFANGTDYPPNEGFCPCRQSGIQNVSSCRLNAPMFISHPHFYNADPSLVDAVEGLHPSREEHALFLDVHPVTGIPMNCSIKLQLNQYMKQVSGILQTGKIQPVVMPLLWFAESGYIDGSVLSQFYTNLVLIPSILDYLQYIFLGLSVPLIISAALVMMSQKHKITESLELEGSCGGHLLQPLCSSRVT", "length": 491, "header": "tr|A0A8V0ZGQ0-1|A0A3Q2TTF7_CHICK Computationally mapped isoform of Scavenger receptor class B member 1 OS=Gallus gallus OX=9031 GN=SCARB1 PE=1 SV=1 CANONICAL=A0A3Q2TTF7-1" }, "locus": { "chromosome": "15", "start_pos": 4545061, "end_pos": 4530840, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050810.1", "url": "https://www.ensembl.org/id/ENSGALT00010050810.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030001.1", "url": "https://www.ensembl.org/id/ENSGALP00010030001.1" } ] } }, { "isoform_ac": "A0A8V0ZGQ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TTF7/entry#A0A8V0ZGQ6-1", "sequence": { "sequence": "MRIARRSGCFRAALPACSILKISAGNVRIDPSSISFNMWRDIPVPFYLTVNLFEVQNPQEVLQGAKPKVNQRGPYVYREFKYKTNITFHDNDTVSYLEYRQLFFRPDLSNGTEDEYIVMPNILMLGAAVMMENLPSFVKLLLSGALAGLKQEAFINRTVGEILWGYEDPLLDTINALVPGLIPYKGKFGIFIEFNNTNSGLFTVNTGMKNISQVHMVDSWNGLKKVNYWRTNECNMINGTAGEMWPPYMSPTSLEFYSPDACRSMTLVYEQSGKFKGVPTYRFVAPKTLFANGTDYPPNEGFCPCRQSGIQNVSSCRLNAPMFISHPHFYNADPSLVDAVEGLHPSREEHALFLDVHPVTGIPMNCSIKLQLNQYMKQVSGILQTGKIQPVVMPLLWFAESGYIDGSVLSQFYTNLVLIPSILDYLQYIFLGLSVPLIISAALVMMSQKSSKEKHPHDPTTQSPPPQPSETTPLLQDTGTQSQDTAEA", "length": 488, "header": "tr|A0A8V0ZGQ6-1|A0A3Q2TTF7_CHICK Computationally mapped isoform of Scavenger receptor class B member 1 OS=Gallus gallus OX=9031 GN=SCARB1 PE=1 SV=1 CANONICAL=A0A3Q2TTF7-1" }, "locus": { "chromosome": "15", "start_pos": 4546733, "end_pos": 4531067, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050815.1", "url": "https://www.ensembl.org/id/ENSGALT00010050815.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030006.1", "url": "https://www.ensembl.org/id/ENSGALP00010030006.1" } ] } }, { "isoform_ac": "F1NAN9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TTF7/entry#F1NAN9-1", "sequence": { "sequence": "MVAAGRRVAVGLGAVGAVCLLLGGCLLLAGPAIVKEQVLKNVRIDPSSISFNMWRDIPVPFYLTVNLFEVQNPQEVLQGAKPKVNQRGPYVYREFKYKTNITFHDNDTVSYLEYRQLFFRPDLSNGTEDEYIVMPNILMLGAAVMMENLPSFVKLLLSGALAGLKQEAFINRTVGEILWGYEDPLLDTINALVPGLIPYKGKFGIFIEFNNTNSGLFTVNTGMKNISQVHMVDSWNGLKKVNYWRTNECNMINGTAGEMWPPYMSPTSLEFYSPDACRSMTLVYEQSGKFKGVPTYRFVAPKTLFANGTDYPPNEGFCPCRQSGIQNVSSCRLNAPMFISHPHFYNADPSLVDAVEGLHPSREEHALFLDVHPVTGIPMNCSIKLQLNQYMKQVSGILQTGKIQPVVMPLLWFAESGYIDGSVLSQFYTNLVLIPSILDYLQYIFLGLSVPLIISAALVMMSQEKCSLFWSSNKKNSDSNKAAQAPPAGKLPPVKVLREARL", "length": 502, "header": "tr|F1NAN9-1|A0A3Q2TTF7_CHICK Computationally mapped isoform of Scavenger receptor class B member 1 OS=Gallus gallus OX=9031 GN=SCARB1 PE=1 SV=4 CANONICAL=A0A3Q2TTF7-1" }, "locus": { "chromosome": "15", "start_pos": 4544523, "end_pos": 4530840, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050807.1", "url": "https://www.ensembl.org/id/ENSGALT00010050807.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029998.1", "url": "https://www.ensembl.org/id/ENSGALP00010029998.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:416814", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416814", "resource": "KEGG Pathway" }, { "id": "R-GGA-3000471", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3000471", "resource": "Reactome", "description": "Scavenging by Class B Receptors" }, { "id": "R-GGA-8964011", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8964011", "resource": "Reactome", "description": "HDL clearance" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A286ZVH8-1", "protein_name": "Scavenger receptor class B member 1", "gene_name": "SCARB1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGSRSRARQVAAALGFVGLLLAALGAVMIVMVPSIIKQQVLKNVRIDPSSLSFNMWKEIPVPFYLSVYFFDVINPNEILQGQKPQVRERGPYVYREFRHKSNITFNDNDTVSFLEYRSYQFQPHKSRGLESDYIVIPNILVLSASVMMEDRPMSLKLIMTFAFSALGERAFVNRTVGEIMWGYEDPLIHLINKYFPNMFPFKGKFGLFAELNNSDSGLFTVFTGVKDFSRIHLVDKWNGLSKVNFWHSDQCNMINGTSGQMWAPFMTPESSLEFYSPEACRSMKLIYKEQGVFEGIPTFRFVAPNTLFANGSVYPPNEGFCPCMESGIQNVSTCRFNAPLFLSHPHFYNADPVLAEAVSGLHPNTEEHSLFLDIHPVTGIPMNCSVKLQLSLYIKSVKGIGQTGKIEPVVLPLLWFAESGAMEGETLQTFYTQLVLMPKVLHYAQYVLLALGCVLLFIPIVYQIRSQGPKDAESQPSLAPQSDQLPSPYTPLLQDSLSGQPTSPQI", "length": 506 }, "evidence": [ { "id": "A0A3Q2TTF7", "url": "https://omabrowser.org/oma/group/A0A3Q2TTF7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O18824-1", "protein_name": "Scavenger receptor class B member 1", "gene_name": "SCARB1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGNLSRARRVTAALGFIGLLFAVLGIIMIVMVPSIIKQQVLKNVRIDPNSLSFNMWKEIPVPFYLSVYFFNIVNPEGIIQGQKPQVQEHGPYVYREFRHKSNITFNNNDTVSFLEYRSYQFQPDKSRGQESDYIVMPNILVLSASMMMENRPGLLKLMMTLAFSTLGQRAFMNRTVGEIMWGYDDPLIHLINQYFPNSLPFKGKFGLFAELNNSDSGLFTVFTGVKNFSRIHLVDKWNGVSKVNYWHSDQCNMINGTSGQMWAPFMTPESSLEFYSPEACRSMKLVYKEQGVFGGIPTFRFVAPSTLFANGSVYPPNEGFCPCRESGIQNVSTCRFNAPLFLSHPHFYNADPVLAEAVSGLHPNPKEHSLFLDIHPVTGIPMNCSVKLQLSLFVKSVKGIGQTGNIQPVVLPLMWFEESGAMEGETLETFYIQLVLMPKVLHYAQYVLLALGCVLLLIPIIYQIRSQEKCYLFWISFKKGSKDKEAVQAYSEFLMTSAPKGTVLQEARL", "length": 509 }, "evidence": [ { "id": "A0A3Q2TTF7", "url": "https://omabrowser.org/oma/group/A0A3Q2TTF7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P97943-1", "protein_name": "Scavenger receptor class B member 1", "gene_name": "Scarb1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGVSSRARWVALGLGVLGLLCAALGVIMILMVPSLIKQQVLKNVRIDPSSLSFGMWKEIPVPFYLSVYFFEVVNPSEVLNGQKPVVRERGPYVYREFRQKVNITFNDNDTVSYIENRSLRFQPDRSQGSESDYIVLPNILVLGGAVMMEDKPTSLKLLMTLGLVTMGQRAFMNRTVGEILWGYEDPFVNFLSKYFPDMFPIKGKFGLFVGMNDSSSGVFTVFTGVQNFSKIHLVDKWNGLSEVNYWHSEQCNMINGTAGQMWAPFMTPESSLEFFSPEACRSMKLTYQESRVFEGIPTYRFTAPDTLFANGSVYPPNEGFCPCRESGIQNVSTCRFGAPLFLSQPHFYNADPVLSEAVLGLNPDPKEHSLFLDIHPVTGIPMNCSVKMQLSLYIKSVKGVGQTGKIEPVVLPLLWFEQSGMMGGKTLNTFYTQLVLMPQVLHYAQYVLLGLGGLLLLVPIIYQLRSQEKCFLFWSGSKKGSQDKEAMQAYSESLMSPAAKGTVLQEAKL", "length": 509 }, "evidence": [ { "id": "A0A3Q2TTF7", "url": "https://omabrowser.org/oma/group/A0A3Q2TTF7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q61009-1", "protein_name": "Scavenger receptor class B member 1", "gene_name": "Scarb1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGGSSRARWVALGLGALGLLFAALGVVMILMVPSLIKQQVLKNVRIDPSSLSFGMWKEIPVPFYLSVYFFEVVNPNEVLNGQKPVVRERGPYVYREFRQKVNITFNDNDTVSFVENRSLHFQPDKSHGSESDYIVLPNILVLGGSILMESKPVSLKLMMTLALVTMGQRAFMNRTVGEILWGYDDPFVHFLNTYLPDMLPIKGKFGLFVGMNNSNSGVFTVFTGVQNFSRIHLVDKWNGLSKIDYWHSEQCNMINGTSGQMWAPFMTPESSLEFFSPEACRSMKLTYNESRVFEGIPTYRFTAPDTLFANGSVYPPNEGFCPCRESGIQNVSTCRFGAPLFLSHPHFYNADPVLSEAVLGLNPNPKEHSLFLDIHPVTGIPMNCSVKMQLSLYIKSVKGIGQTGKIEPVVLPLLWFEQSGAMGGKPLSTFYTQLVLMPQVLHYAQYVLLGLGGLLLLVPIICQLRSQEKCFLFWSGSKKGSQDKEAIQAYSESLMSPAAKGTVLQEAKL", "length": 509 }, "evidence": [ { "id": "A0A3Q2TTF7", "url": "https://omabrowser.org/oma/group/A0A3Q2TTF7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8WTV0-1", "protein_name": "Scavenger receptor class B member 1", "gene_name": "SCARB1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGCSAKARWAAGALGVAGLLCAVLGAVMIVMVPSLIKQQVLKNVRIDPSSLSFNMWKEIPIPFYLSVYFFDVMNPSEILKGEKPQVRERGPYVYREFRHKSNITFNNNDTVSFLEYRTFQFQPSKSHGSESDYIVMPNILVLGAAVMMENKPMTLKLIMTLAFTTLGERAFMNRTVGEIMWGYKDPLVNLINKYFPGMFPFKDKFGLFAELNNSDSGLFTVFTGVQNISRIHLVDKWNGLSKVDFWHSDQCNMINGTSGQMWPPFMTPESSLEFYSPEACRSMKLMYKESGVFEGIPTYRFVAPKTLFANGSIYPPNEGFCPCLESGIQNVSTCRFSAPLFLSHPHFLNADPVLAEAVTGLHPNQEAHSLFLDIHPVTGIPMNCSVKLQLSLYMKSVAGIGQTGKIEPVVLPLLWFAESGAMEGETLHTFYTQLVLMPKVMHYAQYVLLALGCVLLLVPVICQIRSQVGAGQRAARADSHSLACWGKGASDRTLWPTAAWSPPPAAVLRLCRSGSGHCWGLRSTLASFACRVATTLPVLEGLGPSLGGGTGS", "length": 552 }, "evidence": [ { "id": "A0A3Q2TTF7", "url": "https://omabrowser.org/oma/group/A0A3Q2TTF7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "caveola", "id": "GO:0005901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005901", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TTF7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TTF7" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TTF7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TTF7" } ], "pmid": "" }, { "name": "cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TTF7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TTF7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 21, "go_terms": [ { "name": "adhesion of symbiont to host", "id": "GO:0044406", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044406", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TTF7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TTF7" } ], "pmid": "" }, { "name": "positive regulation of sphingolipid mediated signaling pathway", "id": "GO:1902070", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902070", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TTF7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TTF7" } ], "pmid": "" }, { "name": "phospholipid transport", "id": "GO:0015914", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015914", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TTF7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TTF7" } ], "pmid": "" }, { "name": "cholesterol efflux", "id": "GO:0033344", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033344", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TTF7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TTF7" } ], "pmid": "" }, { "name": "high-density lipoprotein particle remodeling", "id": "GO:0034375", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034375", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TTF7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TTF7" } ], "pmid": "" }, { "name": "cholesterol homeostasis", "id": "GO:0042632", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042632", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TTF7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TTF7" } ], "pmid": "" }, { "name": "reverse cholesterol transport", "id": "GO:0043691", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043691", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TTF7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TTF7" } ], "pmid": "" }, { "name": "low-density lipoprotein particle clearance", "id": "GO:0034383", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034383", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TTF7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TTF7" } ], "pmid": "" }, { "name": "high-density lipoprotein particle clearance", "id": "GO:0034384", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034384", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TTF7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TTF7" } ], "pmid": "" }, { "name": "triglyceride homeostasis", "id": "GO:0070328", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070328", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TTF7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TTF7" } ], "pmid": "" }, { "name": "cholesterol import", "id": "GO:0070508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070508", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TTF7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TTF7" } ], "pmid": "" }, { "name": "positive regulation of cholesterol storage", "id": "GO:0010886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010886", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TTF7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TTF7" } ], "pmid": "" }, { "name": "plasma lipoprotein particle clearance", "id": "GO:0034381", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034381", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TTF7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TTF7" } ], "pmid": "" }, { "name": "vitamin transmembrane transport", "id": "GO:0035461", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035461", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TTF7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TTF7" } ], "pmid": "" }, { "name": "positive regulation of nitric oxide mediated signal transduction", "id": "GO:0010750", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010750", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TTF7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TTF7" } ], "pmid": "" }, { "name": "positive regulation of triglyceride biosynthetic process", "id": "GO:0010867", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010867", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TTF7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TTF7" } ], "pmid": "" }, { "name": "lipopolysaccharide transport", "id": "GO:0015920", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015920", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TTF7", 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The reference sequence was derived from JAENSK010000060.1. 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{ "id": "A0A1D5PPP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PPP7/entry#names_and_taxonomy" } ] }, { "name": "3.4.22.59", "type": "synonym", "evidence": [ { "id": "A0A1D5PPP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PPP7/entry#names_and_taxonomy" } ] }, { "name": "CASP-6", "type": "synonym", "evidence": [ { "id": "A0A1D5PPP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PPP7/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Cysteine protease that plays essential roles in programmed cell death, development and innate immunity (PubMed:11953316). Acts as a non-canonical executioner caspase during apoptosis: localizes in the nucleus and cleaves the nuclear structural protein lamin-A/LMNA thereby inducing nuclear shrinkage and fragmentation (PubMed:11953316). Lamin-A/LMNA cleavage is required for chromatin condensation and nuclear disassembly during apoptotic execution (PubMed:11953316). Plays an essential role in defense against viruses by acting as a central mediator of the ZBP1-mediated pyroptosis, apoptosis, and necroptosis (PANoptosis), independently of its cysteine protease activity. PANoptosis is a unique inflammatory programmed cell death, which provides a molecular scaffold that allows the interactions and activation of machinery required for inflammasome/pyroptosis, apoptosis and necroptosis (By similarity).", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PPP7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PPP7#function" }, { "database": "PubMed", "id": "11953316", "url": "https://glygen.org/publication/PubMed/11953316" }, { "database": "UniProtKB", "id": "P55212", "url": "https://www.uniprot.org/uniprotkb/P55212#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PPP7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PPP7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CASP6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PPP7", "locus": { "chromosome": "4", "start_pos": 57673424, "end_pos": 57664200, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010003879", "url": "https://www.ensembl.org/id/ENSGALG00010003879" } ] } } ], "crossref": [ { "id": "A0A1D5PPP7", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PPP7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000012186", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000012186", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00032", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00032", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "395477", "url": "https://www.ncbi.nlm.nih.gov/gene/395477", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001309", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001309", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002138", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002138", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002398", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002398", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011600", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011600", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015917", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015917", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029030", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029030", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033139", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033139", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:395477", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395477", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A1D5PPP7", "url": "https://www.orthodb.org/?gene=A0A1D5PPP7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10454", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10454", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10454:SF206", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10454:SF206", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00656", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00656", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:A0A1D5PPP7", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:A0A1D5PPP7", "database": "PRO", "categories": [ "Protein" ] }, { "id": "A0A1D5PPP7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PPP7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PPP7-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PPP7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSGAERRPAAGRVQLDSKPTPTTTADGNQNITEVDAFDKRQTFDPAVQYKMNHQRRGVALIFNHEHFFWHLRLPDRRGTLADRNNLKRSLTDLGFEVRIFDDLKAEDVLKKVFEASRDDYSNADCFVCVFLSHGENDHVYAYDAQIKIETITNMFRGDKCQSLVGKPKIFIIQACRGDKHDDPVLVQDSVDSKDETTVNQTEVDAAGVYTLPAGADFIMCYSVAQGYFSHRETVNGSWYIQDLCEALGKHGSSLEFTELLTVVNRKVSHRKVDICRDINAIGKKQIPCFASMLTKKLYFHPKSK", "length": 304, "header": "sp|A0A1D5PPP7-1|CASP6_CHICK Isoform 1 of Caspase-6 OS=Gallus gallus OX=9031 GN=CASP6 PE=2 SV=2 CANONICAL=A0A1D5PPP7-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PPP7-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PPP7/entry#A0A1D5PPP7-1", "sequence": { "sequence": 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Reprod.", "date": "2000", "authors": "Johnson A L, Bridgham J T", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PPP7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PPP7" } ], "reference": [ { "type": "PubMed", "id": "10684799", "url": "https://glygen.org/publication/PubMed/10684799" } ] }, { "title": "Caspase-6 gene disruption reveals a requirement for lamin A cleavage in apoptotic chromatin condensation.", "journal": "The EMBO journal", "date": "2002-04-15", "authors": "Ruchaud Sandrine, Korfali Nadia, Villa Pascal, Kottke Timothy J, Dingwall Colin, Kaufmann Scott H, Earnshaw William C", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PPP7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PPP7" } ], "reference": [ { "type": "PubMed", "id": "11953316", "url": "https://glygen.org/publication/PubMed/11953316" } ] }, { "title": "Sequence and comparative analysis of the chicken genome provide unique perspectives on vertebrate evolution.", "journal": "Nature", "date": 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"MDSKELLKSSDQDETRKNALMSTKGGIVMDFHPPFRGGASAQAPVSAAPLPVSSQSDSAQQPALADFSKGLVNNVPPPDLSKAVSLSMGLYMGETDAKVMGNDLGFSQQGQTGISSGETDFRLLEESIASLNKSSSLAEDAKGAVSSEAPLEPDFVGMAGRGPLEPGASVQSQVGSNGGSLKLFSEDQSTLDILQDLELPSVSPGKEPNGSPWRLDPLLDDGGLLSPISADDTFLLEGNLGEDCKPPILSDTKPKINDRGDLLPSSKMPMPQVKTEKEDFIELCTPGIKQENVGPIYCQANFSGSNMLGTKVSAISIHGVSTSGGQMYHYDLNTASLSQQQDQKPIFNIIPSLPAGSENWNRCQGSGDEALAPLGTLNLSGRPAFSNGYSSPGLRSDVSSSPSTTSATAGPPPKLCLVCSDEASGCHYGVLTCGSCKVFFKRAVEGQHNYLCAGRNDCIIDKIRRKNCPACRYRKCLQAGMNLEARKTKKKIKGIQQTTATGTREAAEAAGNKSVVPASLPQLTPTLVSLLEVIEPEVLYSGYDSTLPDSSWRIMSTLNMLGGRQVVAAVKWAKAIPGFRNLHLDDQMTLLQYSWMFLMAFALGWRSYKQSNGNLLCFAPDLIINEQRMNLPCMYEQCKHMLMVARELSRLQVSYEEYLCMKTLLLLSTIPKEGLKSQTLFEEIRMTYIKELGKAIVKREGNSSQNWQRFYQLTKLLDSMHDVVENLLSFCFQTFLDKSMSIEFPEMLAEIISNQIPKYSNGNIKKLLFHQK", "length": 772, "header": "tr|A0A1D5PRD7-1|A0A1D5PRD7_CHICK Isoform 1 of Glucocorticoid receptor OS=Gallus gallus OX=9031 GN=NR3C1 PE=1 SV=1 CANONICAL=A0A1D5PRD7-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PRD7-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRD7/entry#A0A1D5PRD7-1", "sequence": { "sequence": "MDSKELLKSSDQDETRKNALMSTKGGIVMDFHPPFRGGASAQAPVSAAPLPVSSQSDSAQQPALADFSKGLVNNVPPPDLSKAVSLSMGLYMGETDAKVMGNDLGFSQQGQTGISSGETDFRLLEESIASLNKSSSLAEDAKGAVSSEAPLEPDFVGMAGRGPLEPGASVQSQVGSNGGSLKLFSEDQSTLDILQDLELPSVSPGKEPNGSPWRLDPLLDDGGLLSPISADDTFLLEGNLGEDCKPPILSDTKPKINDRGDLLPSSKMPMPQVKTEKEDFIELCTPGIKQENVGPIYCQANFSGSNMLGTKVSAISIHGVSTSGGQMYHYDLNTASLSQQQDQKPIFNIIPSLPAGSENWNRCQGSGDEALAPLGTLNLSGRPAFSNGYSSPGLRSDVSSSPSTTSATAGPPPKLCLVCSDEASGCHYGVLTCGSCKVFFKRAVEGQHNYLCAGRNDCIIDKIRRKNCPACRYRKCLQAGMNLEARKTKKKIKGIQQTTATGTREAAEAAGNKSVVPASLPQLTPTLVSLLEVIEPEVLYSGYDSTLPDSSWRIMSTLNMLGGRQVVAAVKWAKAIPGFRNLHLDDQMTLLQYSWMFLMAFALGWRSYKQSNGNLLCFAPDLIINEQRMNLPCMYEQCKHMLMVARELSRLQVSYEEYLCMKTLLLLSTIPKEGLKSQTLFEEIRMTYIKELGKAIVKREGNSSQNWQRFYQLTKLLDSMHDVVENLLSFCFQTFLDKSMSIEFPEMLAEIISNQIPKYSNGNIKKLLFHQK", "length": 772, "header": "tr|A0A1D5PRD7-1|A0A1D5PRD7_CHICK Isoform 1 of Glucocorticoid receptor OS=Gallus gallus OX=9031 GN=NR3C1 PE=1 SV=1 CANONICAL=A0A1D5PRD7-1" }, "locus": { "chromosome": "13", "start_pos": 17051980, "end_pos": 17001488, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040409.1", "url": "https://www.ensembl.org/id/ENSGALT00010040409.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023444.1", "url": "https://www.ensembl.org/id/ENSGALP00010023444.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-3371497", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3371497", "resource": "Reactome", "description": "HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand" }, { "id": "R-GGA-383280", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-383280", "resource": "Reactome", "description": "Nuclear Receptor transcription pathway" }, { "id": "R-GGA-4090294", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4090294", "resource": "Reactome", "description": "SUMOylation of intracellular receptors" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287B660-1", "protein_name": "Glucocorticoid receptor", "gene_name": "NR3C1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MNVYAVQEWRETKHSSYPPGAFIVISSGEFSSVWHLPSKDKEVLSEAASVKCLGRKLIPTDGPQGIADPPSREEIPSSVLGRERAHVMDFYKSLRGGTPVKVSAASPSLAAVSQPDSKQQRLAVDFPKGSGSNAQQPDLSKAVSLSMGLYMGETETKVMGSDLGFPQQGQISLSSGETDFRLLEESIANLSRSTSVPENPKSSASAAGSAAPAEKAFPKTHSDGAPEQPNVKGQTGTNGGNVKLFTTDQSTFDIWRKKLQDLELPSGSPGKETSESPWSSDLLIDENCLLSPLAGEEDPFLLEGSSTEDCKPLVLPDTKPKVKDNGELILPSPNSVPLPQVKTEKEDFIELCTPGVIKQEKLGPAYCQASFSGANIIGGKMSAISVHGVSTSGGQLYHYDMNTAASLSKQQEQKPLFNVIPPIPVGSENWNRCQGSGDDNLTSLGTLNFSGRSVFSNGYSSPGMRPDVSSPPSSSSAATGPPPKLCLVCSDEASGCHYGVLTCGSCKVFFKRAVEGQHNYLCAGRNDCIIDKIRRKNCPACRYRKCLQAGMNLEARKTKKKIKGIQQATTGVSQETSENSANKTIVPATLPQLTPTLVSLLEVIEPEVLYAGYDSSIPDSTWRIMTALNMLGGRQVIAAVKWAKAIPGFRNLHLDDQMTLLQYSWMFLMAFALGWRSYRQSSASLLCFAPDLVINEQRMALPCMYDQCRHMLYVSSELQRLQVSYEEYLCMKTLLLLSSVPKDGLKSQELFDEIRMTYIKELGKAIVKREGNSSQNWQRFYQLTKLLDSMHDVVENLLNYCFQTFLDKNMSIEFPEMLAEIITNQLPKYSSGNIKKLLFHQK", "length": 842 }, "evidence": [ { "id": "A0A1D5PRD7", "url": "https://omabrowser.org/oma/group/A0A1D5PRD7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P04150-1", "protein_name": "Glucocorticoid receptor", "gene_name": "NR3C1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDSKESLTPGREENPSSVLAQERGDVMDFYKTLRGGATVKVSASSPSLAVASQSDSKQRRLLVDFPKGSVSNAQQPDLSKAVSLSMGLYMGETETKVMGNDLGFPQQGQISLSSGETDLKLLEESIANLNRSTSVPENPKSSASTAVSAAPTEKEFPKTHSDVSSEQQHLKGQTGTNGGNVKLYTTDQSTFDILQDLEFSSGSPGKETNESPWRSDLLIDENCLLSPLAGEDDSFLLEGNSNEDCKPLILPDTKPKIKDNGDLVLSSPSNVTLPQVKTEKEDFIELCTPGVIKQEKLGTVYCQASFPGANIIGNKMSAISVHGVSTSGGQMYHYDMNTASLSQQQDQKPIFNVIPPIPVGSENWNRCQGSGDDNLTSLGTLNFPGRTVFSNGYSSPSMRPDVSSPPSSSSTATTGPPPKLCLVCSDEASGCHYGVLTCGSCKVFFKRAVEGQHNYLCAGRNDCIIDKIRRKNCPACRYRKCLQAGMNLEARKTKKKIKGIQQATTGVSQETSENPGNKTIVPATLPQLTPTLVSLLEVIEPEVLYAGYDSSVPDSTWRIMTTLNMLGGRQVIAAVKWAKAIPGFRNLHLDDQMTLLQYSWMFLMAFALGWRSYRQSSANLLCFAPDLIINEQRMTLPCMYDQCKHMLYVSSELHRLQVSYEEYLCMKTLLLLSSVPKDGLKSQELFDEIRMTYIKELGKAIVKREGNSSQNWQRFYQLTKLLDSMHEVVENLLNYCFQTFLDKTMSIEFPEMLAEIITNQIPKYSNGNIKKLLFHQK", "length": 777 }, "evidence": [ { "id": "A0A1D5PRD7", "url": "https://omabrowser.org/oma/group/A0A1D5PRD7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P06536-1", "protein_name": "Glucocorticoid receptor", "gene_name": "Nr3c1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDSKESLAPPGRDEVPGSLLGQGRGSVMDFYKSLRGGATVKVSASSPSVAAASQADSKQQRILLDFSKGSTSNVQQRQQQQQQQQQQQQQQQQQQQPDLSKAVSLSMGLYMGETETKVMGNDLGYPQQGQLGLSSGETDFRLLEESIANLNRSTSVPENPKSSTSATGCATPTEKEFPKTHSDASSEQQNRKSQTGTNGGSVKLYPTDQSTFDLLKDLEFSAGSPSKDTNESPWRSDLLIDENLLSPLAGEDDPFLLEGNTNEDCKPLILPDTKPKIKDTGDTILSSPSSVALPQVKTEKDDFIELCTPGVIKQEKLGPVYCQASFSGTNIIGNKMSAISVHGVSTSGGQMYHYDMNTASLSQQQDQKPVFNVIPPIPVGSENWNRCQGSGEDSLTSLGALNFPGRSVFSNGYSSPGMRPDVSSPPSSSSAATGPPPKLCLVCSDEASGCHYGVLTCGSCKVFFKRAVEGQHNYLCAGRNDCIIDKIRRKNCPACRYRKCLQAGMNLEARKTKKKIKGIQQATAGVSQDTSENPNKTIVPAALPQLTPTLVSLLEVIEPEVLYAGYDSSVPDSAWRIMTTLNMLGGRQVIAAVKWAKAILGLRNLHLDDQMTLLQYSWMFLMAFALGWRSYRQSSGNLLCFAPDLIINEQRMSLPCMYDQCKHMLFVSSELQRLQVSYEEYLCMKTLLLLSSVPKEGLKSQELFDEIRMTYIKELGKAIVKREGNSSQNWQRFYQLTKLLDSMHEVVENLLTYCFQTFLDKTMSIEFPEMLAEIITNQIPKYSNGNIKKLLFHQK", "length": 795 }, "evidence": [ { "id": "A0A1D5PRD7", "url": "https://omabrowser.org/oma/group/A0A1D5PRD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P06537-1", "protein_name": "Glucocorticoid receptor", "gene_name": "Nr3c1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDSKESLAPPGRDEVPSSLLGRGRGSVMDLYKTLRGGATVKVSASSPSVAAASQADSKQQRILLDFSKGSASNAQQQQQQQQQQQQQQQQQPQPDLSKAVSLSMGLYMGETETKVMGNDLGYPQQGQLGLSSGETDFRLLEESIANLNRSTSRPENPKSSTPAAGCATPTEKEFPQTHSDPSSEQQNRKSQPGTNGGSVKLYTTDQSTFDILQDLEFSAGSPGKETNESPWRSDLLIDENLLSPLAGEDDPFLLEGDVNEDCKPLILPDTKPKIQDTGDTILSSPSSVALPQVKTEKDDFIELCTPGVIKQEKLGPVYCQASFSGTNIIGNKMSAISVHGVSTSGGQMYHYDMNTASLSQQQDQKPVFNVIPPIPVGSENWNRCQGSGEDNLTSLGAMNFAGRSVFSNGYSSPGMRPDVSSPPSSSSTATGPPPKLCLVCSDEASGCHYGVLTCGSCKVFFKRAVEGQHNYLCAGRNDCIIDKIRRKNCPACRYRKCLQAGMNLEARKTKKKIKGIQQATAGVSQDTSENANKTIVPAALPQLTPTLVSLLEVIEPEVLYAGYDSSVPDSAWRIMTTLNMLGGRQVIAAVKWAKAIPGFRNLHLDDQMTLLQYSWMFLMAFALGWRSYRQASGNLLCFAPDLIINEQRMTLPCMYDQCKHMLFISTELQRLQVSYEEYLCMKTLLLLSSVPKEGLKSQELFDEIRMTYIKELGKAIVKREGNSSQNWQRFYQLTKLLDSMHDVVENLLSYCFQTFLDKSMSIEFPEMLAEIITNQIPKYSNGNIKKLLFHQK", "length": 792 }, "evidence": [ { "id": "A0A1D5PRD7", "url": "https://omabrowser.org/oma/group/A0A1D5PRD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 19, "go_terms": [ { "name": "astrocyte differentiation", "id": "GO:0048708", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048708", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PRD7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRD7" } ], "pmid": "" }, { "name": "somatotropin secreting cell differentiation", "id": "GO:0060126", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060126", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PRD7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRD7" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PRD7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRD7" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PRD7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRD7" } ], "pmid": "" }, { "name": "synaptic transmission, glutamatergic", "id": "GO:0035249", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035249", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PRD7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRD7" } ], "pmid": "" }, { "name": "cellular response to dexamethasone stimulus", "id": "GO:0071549", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071549", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PRD7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRD7" } ], "pmid": "" }, { "name": "chromatin organization", "id": "GO:0006325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006325", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PRD7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRD7" } ], "pmid": "" }, { "name": "cellular response to transforming growth factor beta stimulus", "id": "GO:0071560", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071560", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PRD7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRD7" } ], "pmid": "" }, { "name": "response to heat", "id": "GO:0009408", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009408", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PRD7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRD7" } ], "pmid": "" }, { "name": "cellular response to aldosterone", "id": "GO:1904045", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904045", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PRD7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRD7" } ], "pmid": "" }, { "name": "regulation of corticotropin secretion", "id": "GO:0051459", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051459", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PRD7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRD7" } ], "pmid": "" }, { "name": "cellular response to corticosterone stimulus", "id": "GO:0071386", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071386", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PRD7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRD7" } ], "pmid": "" }, { "name": "nuclear receptor-mediated steroid hormone signaling pathway", "id": "GO:0030518", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030518", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PRD7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRD7" } ], "pmid": "" }, { "name": "positive regulation of miRNA transcription", "id": "GO:1902895", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902895", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PRD7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRD7" } ], "pmid": "" }, { "name": "growth hormone secretion", "id": "GO:0030252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030252", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PRD7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRD7" } ], "pmid": "" }, { "name": "cellular response to corticotropin-releasing hormone stimulus", "id": "GO:0071376", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071376", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PRD7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRD7" } ], "pmid": "" }, { "name": "motor behavior", "id": "GO:0061744", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061744", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PRD7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRD7" } ], "pmid": "" }, { "name": "neuroinflammatory response", "id": "GO:0150076", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0150076", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PRD7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRD7" } ], "pmid": "" }, { "name": "microglia differentiation", "id": "GO:0014004", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014004", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PRD7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRD7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 13, "go_terms": [ { "name": "nuclear glucocorticoid receptor activity", "id": "GO:0004883", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004883", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PRD7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRD7" } ], "pmid": "" }, { "name": "estrogen response element binding", "id": "GO:0034056", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034056", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PRD7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRD7" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PRD7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRD7" } ], "pmid": "" }, { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PRD7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRD7" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PRD7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRD7" } ], "pmid": "" }, { "name": "DNA-binding transcription repressor activity, RNA polymerase II-specific", "id": "GO:0001227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001227", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PRD7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRD7" } ], "pmid": "" }, { "name": "nuclear receptor activity", "id": "GO:0004879", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004879", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PRD7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRD7" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PRD7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRD7" } ], "pmid": "" }, { "name": "TBP-class protein binding", "id": "GO:0017025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017025", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PRD7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRD7" } ], "pmid": "" }, { "name": "Hsp90 protein binding", "id": "GO:0051879", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051879", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PRD7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRD7" } ], "pmid": "" }, { "name": "core promoter sequence-specific DNA binding", "id": "GO:0001046", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001046", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PRD7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRD7" } ], "pmid": "" }, { "name": "steroid hormone binding", "id": "GO:1990239", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990239", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PRD7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRD7" } ], "pmid": "" }, { "name": "promoter-specific chromatin binding", "id": "GO:1990841", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990841", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PRD7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRD7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 11, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PRD7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRD7" } ], "pmid": "" }, { "name": 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"sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A1D5PRL4-1", "uniprot_ac": "A0A1D5PRL4", "uniprot_id": "A0A1D5PRL4_CHICK", "mass": { "chemical_mass": 50299.0, "monoisotopic_mass": 50299.0 }, "refseq": { "ac": "XP_040526959", "name": "zinc finger protein ZIC 3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040526959" }, "gene_names": [ { "name": "ZIC3", "type": "recommended", "evidence": [ { "id": "A0A1D5PRL4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRL4" } ] }, { "name": "ZIC3", "type": "synonym", "evidence": [ { "id": "XP_040526959", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040526959" } ] } ], "protein_names": [ { "name": "Zic family member 3", "type": "synonym", "evidence": [ { "id": "A0A1D5PRL4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRL4/entry#names_and_taxonomy" } ] }, { "name": "zinc finger protein ZIC 3", "type": "synonym", "evidence": [ { "id": "XP_040526959", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040526959" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052576.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040526959", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040526959" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PRL4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRL4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ZIC3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRL4", "locus": { "chromosome": "4", "start_pos": 4506519, "end_pos": 4503168, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010017413", "url": "https://www.ensembl.org/id/ENSGALG00010017413" } ] } } ], "crossref": [ { "id": "ENSGALG00000031144", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000031144", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "422251", "url": "https://www.ncbi.nlm.nih.gov/gene/422251", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041643", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041643", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043359", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043359", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056436", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056436", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:422251", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422251", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GTPRHHD", "url": "https://omabrowser.org/oma/group/GTPRHHD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PRL4", "url": "https://www.orthodb.org/?gene=A0A1D5PRL4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45718", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45718", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45718:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45718:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18366", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18366", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23561", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23561", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040526959", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040526959", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PRL4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRL4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PRL4-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRL4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTMLLDGGPQFPALGVGGFAAPRHHEMPGRDPAAGMGLGPFGDSSHAAAAFKLNAAPHDLAAGQSSAFTPQAPGYASALGHHHHHHHHHAGQVPSYGGAAAFNSTRDFLFRNRGSGIADAGSGTAQHGLFGGSPGGLHGPGGIPDSPGYLLFPGLHEQSPSHTSPGGHVDNGQMHLGLRGDLFGRPDPYRAVSSPRTDPYGGAQFHNYNHMNMNMGVNVAAHHHHHHHHHGPGAFFRYMRQPIKQELSCKWLDESHLSRPKKSCDRTFSTMHELVTHVTMEHVGGPEQNNHICYWDECPREGKSFKAKYKLVNHIRVHTGEKPFPCPFPGCGKIFARSENLKIHKRTHTGEKPFKCEFEGCDRRFANSSDRKKHMHVHTSDKPYICKVCDKSYTHPSSLRKHMKVHESQGSDSSPAASSGYESSTPPAVGSAGSKDSTKTPPAALQGNPGHNPGLPPNFNEWYV", "length": 464, "header": "tr|A0A1D5PRL4-1|A0A1D5PRL4_CHICK Isoform 1 of Zic family member 3 OS=Gallus gallus OX=9031 GN=ZIC3 PE=3 SV=1 CANONICAL=A0A1D5PRL4-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PRL4-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRL4/entry#A0A1D5PRL4-1", "sequence": { "sequence": "MTMLLDGGPQFPALGVGGFAAPRHHEMPGRDPAAGMGLGPFGDSSHAAAAFKLNAAPHDLAAGQSSAFTPQAPGYASALGHHHHHHHHHAGQVPSYGGAAAFNSTRDFLFRNRGSGIADAGSGTAQHGLFGGSPGGLHGPGGIPDSPGYLLFPGLHEQSPSHTSPGGHVDNGQMHLGLRGDLFGRPDPYRAVSSPRTDPYGGAQFHNYNHMNMNMGVNVAAHHHHHHHHHGPGAFFRYMRQPIKQELSCKWLDESHLSRPKKSCDRTFSTMHELVTHVTMEHVGGPEQNNHICYWDECPREGKSFKAKYKLVNHIRVHTGEKPFPCPFPGCGKIFARSENLKIHKRTHTGEKPFKCEFEGCDRRFANSSDRKKHMHVHTSDKPYICKVCDKSYTHPSSLRKHMKVHESQGSDSSPAASSGYESSTPPAVGSAGSKDSTKTPPAALQGNPGHNPGLPPNFNEWYV", "length": 464, "header": "tr|A0A1D5PRL4-1|A0A1D5PRL4_CHICK Isoform 1 of Zic family member 3 OS=Gallus gallus OX=9031 GN=ZIC3 PE=3 SV=1 CANONICAL=A0A1D5PRL4-1" }, "locus": { "chromosome": "4", "start_pos": 4505589, "end_pos": 4503215, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042022.1", "url": "https://www.ensembl.org/id/ENSGALT00010042022.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024599.1", "url": "https://www.ensembl.org/id/ENSGALP00010024599.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:422251", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422251", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A5G2R7X0-1", "protein_name": "Zic family member 3", "gene_name": "ZIC3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTMLLDGGPQFPGLGVGSFGAPRHHEMPNREPAGMGLNPFGDSPHAAAAAAAAAAFKLSPAAAHDLSSGQSSAFTPQGSGYANALGHHHHHHHHHHHAGQVPSYGGAASAAFNSTRDFLFRQRGSGLGEAASGSGQHGLFAGSASSLHAPAGIPEPPGYLLFPGLHEQGAGHPSPTGHVDNNQVHLGLRGELFGRADPYRPVASPRTDPYTAGAQFPNYSPMNMNMGVNVAAHHGPGAFFRYMRQPIKQELSCKWIDEAQLSRPKKSCDRTFSTMHELVTHVTMEHVGGPEQNNHVCYWEECPREGKSFKAKYKLVNHIRVHTGEKPFPCPFPGCGKIFARSENLKIHKRTHTGEKPFKCEFEGCDRRFANSSDRKKHMHVHTSDKPYICKVCDKSYTHPSSLRKHMKCCPAWYPGQSLIPDEELDTDVGMQQPALHNTTYPKCRVNAEPTVQEMIY", "length": 457 }, "evidence": [ { "id": "A0A1D5PRL4", "url": "https://omabrowser.org/oma/group/A0A1D5PRL4/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0ABK0LH97-1", "protein_name": "Zic family member 3", "gene_name": "Zic3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGLQSTCWRQLIIRMWPHQNGHSVPGDSRSQGKLQLRVAPRGSPGSAQPPPSLSDYGPSGISFACTLAHFSRIFCVQNAPPMTMLLDGGPQFPGLGVGSFGAPRHHEMPNREPAAMGLNPFGDSTHAAAAAAAAAAFKLSPATAHDLSSGQSSAFTPQGSGYANALGHHHHHHHHHHASQVPTYGGAASAAFNSTRDFLFRQRGSGLSEAASGGGQHGLFAGSASSLHAPAGIPEPPSYLLFPGLHEQGAGHPSPTGHVDNNQVHLGLRGELFGRADPYRPVASPRTDPYAASAQFPNYSPMNMNMGVNVAAHHGPGAFFRYMRQPIKQELSCKWIEEAQLSRPKKSCDRTFSTMHELVTHVTMEHVGGPEQNNHVCYWEECPREGKSFKAKYKLVNHIRVHTGEKPFPCPFPGCGKIFARSENLKIHKRTHTGEKPFKCEFEGCDRRFANSSDRKKHMHVHTSDKPYICKVCDKSYTHPSSLRKHMKVHESQGSDSSPAASSGYESSTPPAIASANSKDTTKTPSAVQTSTSHNPGLPPNFNEWYV", "length": 547 }, "evidence": [ { "id": "A0A1D5PRL4", "url": "https://omabrowser.org/oma/group/A0A1D5PRL4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O60481-1", "protein_name": "Zinc finger protein ZIC 3", "gene_name": "ZIC3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTMLLDGGPQFPGLGVGSFGAPRHHEMPNREPAGMGLNPFGDSTHAAAAAAAAAAFKLSPAAAHDLSSGQSSAFTPQGSGYANALGHHHHHHHHHHHTSQVPSYGGAASAAFNSTREFLFRQRSSGLSEAASGGGQHGLFAGSASSLHAPAGIPEPPSYLLFPGLHEQGAGHPSPTGHVDNNQVHLGLRGELFGRADPYRPVASPRTDPYAAGAQFPNYSPMNMNMGVNVAAHHGPGAFFRYMRQPIKQELSCKWIDEAQLSRPKKSCDRTFSTMHELVTHVTMEHVGGPEQNNHVCYWEECPREGKSFKAKYKLVNHIRVHTGEKPFPCPFPGCGKIFARSENLKIHKRTHTGEKPFKCEFEGCDRRFANSSDRKKHMHVHTSDKPYICKVCDKSYTHPSSLRKHMKVHESQGSDSSPAASSGYESSTPPAIASANSKDTTKTPSAVQTSTSHNPGLPPNFNEWYV", "length": 467 }, "evidence": [ { "id": "A0A1D5PRL4", "url": "https://omabrowser.org/oma/group/A0A1D5PRL4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q62521-1", "protein_name": "Zinc finger protein ZIC 3", "gene_name": "Zic3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTMLLDGGPQFPGLGVGSFGAPRHHEMPNREPAGMGLNPFGDSTHAAAAAAAAAAFKLSPATAHDLSSGQSSAFTPQGSGYANALGHHHHHHHHHHASQVPTYGGAASAAFNSTRDFLFRQRGSGLSEAASGGGQHGLFAGSASSLHAPAGIPEPPSYLLFPGLHEQGAGHPSPTGHVDNNQVHLGLRGELFGRADPYRPVASPRTDPYAASAQFPNYSPMNMNMGVNVAAHHGPGAFFRYMRQPIKQELSCKWIEEAQLSRPKKSCDRTFSTMHELVTHVTMEHVGGPEQNNHVCYWEECPREGKSFKAKYKLVNHIRVHTGEKPFPCPFPGCGKIFARSENLKIHKRTHTGEKPFKCEFEGCDRRFANSSDRKKHMHVHTSDKPYICKVCDKSYTHPSSLRKHMKVHESQGSDSSPAASSGYESSTPPAIASANSKDTTKTPSAVQTSTSHNPGLPPNFNEWYV", "length": 466 }, "evidence": [ { "id": "A0A1D5PRL4", "url": "https://omabrowser.org/oma/group/A0A1D5PRL4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 27, "go_terms": [ { "name": "cranial skeletal system development", "id": "GO:1904888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904888", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PRL4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRL4" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PRL4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRL4" } ], "pmid": "" }, { "name": "stem cell differentiation", "id": "GO:0048863", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048863", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PRL4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRL4" } ], "pmid": "" }, { "name": "lung development", "id": "GO:0030324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030324", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PRL4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRL4" } ], "pmid": "" }, { "name": "central nervous system development", "id": "GO:0007417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007417", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PRL4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRL4" } ], "pmid": "" }, { "name": "skeletal system development", "id": "GO:0001501", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001501", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PRL4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRL4" } ], "pmid": "" }, { "name": "neuron differentiation", "id": "GO:0030182", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030182", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PRL4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRL4" } ], "pmid": "" }, { "name": "face development", "id": "GO:0060324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060324", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PRL4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRL4" } ], "pmid": "" }, { "name": "heart looping", "id": "GO:0001947", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001947", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PRL4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRL4" } ], "pmid": "" }, { "name": "left/right axis specification", "id": "GO:0070986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070986", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PRL4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRL4" } ], "pmid": "" }, { "name": "smoothened signaling pathway", "id": "GO:0007224", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007224", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PRL4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRL4" } ], "pmid": "" }, { "name": "mRNA transcription by RNA polymerase II", "id": "GO:0042789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042789", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PRL4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRL4" } ], "pmid": "" }, { "name": "limb morphogenesis", "id": "GO:0035108", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035108", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PRL4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRL4" } ], "pmid": "" }, { "name": "determination of left/right asymmetry in nervous system", "id": "GO:0035545", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035545", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PRL4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRL4" } ], "pmid": "" }, { "name": "embryonic pattern specification", "id": "GO:0009880", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009880", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PRL4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRL4" } ], "pmid": "" }, { "name": "paraxial mesoderm development", "id": "GO:0048339", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048339", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PRL4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRL4" } ], "pmid": "" }, { "name": "determination of pancreatic left/right asymmetry", "id": "GO:0035469", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035469", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PRL4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRL4" } ], "pmid": "" }, { "name": "determination of digestive tract left/right asymmetry", "id": "GO:0071907", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071907", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PRL4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRL4" } ], "pmid": "" }, { "name": "determination of liver left/right asymmetry", "id": "GO:0071910", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071910", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PRL4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRL4" } ], "pmid": "" }, { "name": "primitive streak formation", "id": "GO:0090009", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090009", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PRL4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRL4" } ], "pmid": "" }, { "name": "olfactory bulb development", "id": "GO:0021772", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021772", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PRL4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRL4" } ], "pmid": "" }, { "name": "neural plate development", "id": "GO:0001840", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001840", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PRL4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRL4" } ], "pmid": "" }, { "name": "axial mesoderm development", "id": "GO:0048318", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048318", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PRL4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRL4" } ], "pmid": "" }, { "name": "germ-line stem cell population maintenance", "id": "GO:0030718", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030718", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PRL4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRL4" } ], "pmid": "" }, { "name": "outer ear morphogenesis", "id": "GO:0042473", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042473", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PRL4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRL4" } ], "pmid": "" }, { "name": "atrial cardiac muscle tissue development", "id": "GO:0003228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003228", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PRL4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRL4" } ], "pmid": "" }, { "name": "central nervous system segmentation", "id": "GO:0035283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035283", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PRL4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRL4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PRL4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRL4" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PRL4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRL4" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PRL4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRL4" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PRL4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRL4" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PRL4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRL4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PRL4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRL4" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PRL4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRL4" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PRL4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRL4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 103, "end_pos": 105, "annotation": "n_glycosylation_sequon" }, { "start_pos": 367, "end_pos": 369, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A1D5PRL4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRL4" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 296, "end_pos": 323, "start_aa": "Asp", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 103, "end_pos": 105 }, { "start_pos": 367, "end_pos": 369 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A1D5PRR9-1", "uniprot_ac": "A0A1D5PRR9", "uniprot_id": "FANCM_CHICK", "mass": { "chemical_mass": 224006.0, "monoisotopic_mass": 224006.0 }, "refseq": {}, "gene_names": [ { "name": "FANCM", "type": "recommended", "evidence": [ { "id": "A0A1D5PRR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRR9" } ] } ], "protein_names": [ { "name": "Fanconi anemia group M protein", "type": "recommended", "evidence": [ { "id": "A0A1D5PRR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRR9/entry#names_and_taxonomy" } ] }, { "name": "3.6.4.13", "type": "synonym", "evidence": [ { "id": "A0A1D5PRR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRR9/entry#names_and_taxonomy" } ] }, { "name": "ATP-dependent RNA helicase FANCM", "type": "synonym", "evidence": [ { "id": "A0A1D5PRR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRR9/entry#names_and_taxonomy" } ] }, { "name": "FAAP250", "type": "synonym", "evidence": [ { "id": "A0A1D5PRR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRR9/entry#names_and_taxonomy" } ] }, { "name": "Fanconi anemia-associated polypeptide of 250 kDa", "type": "synonym", "evidence": [ { "id": "A0A1D5PRR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRR9/entry#names_and_taxonomy" } ] }, { "name": "Protein FACM", "type": "synonym", "evidence": [ { "id": "A0A1D5PRR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRR9/entry#names_and_taxonomy" } ] }, { "name": "Protein Hef ortholog", "type": "synonym", "evidence": [ { "id": "A0A1D5PRR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRR9/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "DNA-dependent ATPase component of the Fanconi anemia (FA) core complex (By similarity). Required for the normal activation of the FA pathway, leading to monoubiquitination of the FANCI-FANCD2 complex in response to DNA damage, cellular resistance to DNA cross-linking drugs, and prevention of chromosomal breakage (PubMed:16116434, PubMed:19465393). In complex with CENPS and CENPX, binds double-stranded DNA (dsDNA), fork-structured DNA (fsDNA) and Holliday junction substrates (By similarity). Its ATP-dependent DNA branch migration activity can process branched DNA structures such as a movable replication fork (By similarity). This activity is strongly stimulated in the presence of CENPS and CENPX (By similarity). In complex with FAAP24, efficiently binds to single-strand DNA (ssDNA), splayed-arm DNA, and 3'-flap substrates (By similarity). In vitro, on its own, strongly binds ssDNA oligomers and weakly fsDNA, but does not bind to dsDNA (By similarity).", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PRR9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRR9#function" }, { "database": "PubMed", "id": "16116434", "url": "https://glygen.org/publication/PubMed/16116434" }, { "database": "PubMed", "id": "19465393", "url": "https://glygen.org/publication/PubMed/19465393" }, { "database": "UniProtKB", "id": "Q8IYD8", "url": "https://www.uniprot.org/uniprotkb/Q8IYD8#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [ { "start_pos": 207, "end_pos": 207, "sequence_org": "D", "sequence_mut": "A", "comment": "Increased sister chromatid exchanges. No effect on FANCD2 monoubiquitination, nor on cisplatin sensitivity.", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PRR9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRR9" }, { "database": "PubMed", "id": "16116434", "url": "https://glygen.org/publication/PubMed/16116434" } ] } ], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PRR9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRR9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FANCM", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRR9", "locus": { "chromosome": "5", "start_pos": 58498352, "end_pos": 58557868, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010018216", "url": "https://www.ensembl.org/id/ENSGALG00010018216" } ] } } ], "crossref": [ { "id": "A0A1D5PRR9", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PRR9", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd12091", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12091", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18033", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18033", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18801", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18801", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd20077", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20077", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "7DA2", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7DA2&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "IPR001650", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001650", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006166", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006166", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010994", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010994", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011335", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011335", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011545", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011545", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014001", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014001", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031879", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031879", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039686", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039686", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044749", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044749", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047418", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047418", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:100857997", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100857997", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A1D5PRR9", "url": "https://www.orthodb.org/?gene=A0A1D5PRR9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14025", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14025", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14025:SF20", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14025:SF20", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "pdb_00007da2", "url": "https://www.rcsb.org/structure/pdb_00007da2", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7DA2", "url": "https://www.rcsb.org/structure/7DA2", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "PF00270", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00270", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00271", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00271", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02732", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02732", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16783", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16783", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:A0A1D5PRR9", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:A0A1D5PRR9", "database": "PRO", "categories": [ "Protein" ] }, { "id": "13065", "url": "https://www.rhea-db.org/rhea/13065", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A1D5PRR9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRR9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PRR9-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRR9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSGGRQRTLPEAWRRAAGPALQAGRDADGNDDDDDELLAAAAAELDPDPNPNVDPNPGPGPEAAAGGFCAAAGALWIYPTNRPERPYQLRMARAALFANTLLCLPTGLGKTFVAAVVMYNFYRWFPSGKVLFLAPTKALVAQQMEACAQLMGIPGRDMAEMTGGTQALSRRELWASRRVFFLTPQIMVNDLSRGTCPAVEVKCLVVDEAHKALGNHAYCQVVKELSRYTTQFRVLALTATPGSDTKAVQQVVSNLLIAQIELCSEDSPEIQPYSHERQVEKIVVPLGEELGGIQRAYIHVLETFAGRLIKLGVLARRDVPSLTKYQIILARDQYRKNPSPQNVGMQPGIIEGDFALCISLYHGYELLQQMGVRSLFIYLCGIMDGSKGLTRTKNELGRNEDFMRLYQQLTDMFSDTCQTSANGNLHKSRTVSENKKEFIYSHPKLKKLEEIVIEHFKSRKMGCSDQTTSGGTCVDTRVMIFSSFRDSVQEIAEMLSRFSPVVRVMTFVGHSTGKSTKGFTQKEQLEVVKRFREGGYNTLVSTCVGEEGLDIGEVDLIICFDAQKSPIRLVQRMGRTGRQRQGRVVVILAEGREERTYNQSQSNRRSIQKAISGNKMLHFYQHSPRMIPEGINPELHRMFITAEKYKPNDSGRLPKGRPSSLHHKSALFSCVTDPKEMHCHENWSLSPEEFEIWDRLYRLKENDGVKEPILPHTRFETLENLDKTSKPEEEAAHKLSLSEWSIWQSRPFPTSMVDHSDRCYHFISVMELIEVMRQEQGDCSYELELQPHLRIEDIHVRRNKGHLSTTSSAFAQKTHSSKRDMARTKRPFVPDVNDNEREFFSIFKTTNTKTPRTAPGLDLEEPELPTDTNGSEPCSARRLTLVASTDQGSPKEEEIEKVTFDLNEFNDLCDDGESTVAHESAAVKDLRLLDKHCSSVGLNHTDLGYSSFTAEKSPASSDLFYLPESHVDSFVLVSSSAELAGLEGAFSCVKGLLAHSPPPVSKLEGIEELLRHEETLCPLPKVSCRSYSGQLPHGDFPSSLAVDQSLLPAESPELEVTIGLSAAVNTCVSKPASTPTAAGGAEERPPGGGSFHSLLGKEGFTANHTDNPPNKHFVQGDEEDSEMKRDVTIDGEKSIHLFEDEHTYKVNDEMPSVDVEPLLRLGSGGHTARPSAGPASQQPPSGDSPRGDTACGEGAARGEMAPGGAWGRGSAAEQALHNSELCDYSQELFSVNFDLGFSIEECEEEIFEGDTDAMNTPKLNSASRSRADVQLTANRKSLNDGCRVQTPPKWDCKGLKGRNISTPLPLQSGHVRDTAVPGGTAGGRTGRGSPGASPPSPATPTGRRVSSAEATRRIRKKVFSTVREETPEVCPTDKVNPNSQRNSFGSSASDALHTTGGRTENLEGTNLHTSRVFPAEGTSSESEEEIVFQRKNRRNNVLRSPDVGSDSDFGSPVCAVRKRRHPLTVSDVSSDDGVDFHKNPNRGTRGCSAAGSKAQLRGVKRQKVRSKVTCKNAARQFLDEEAELSQQDESCVSSDETEDTDKELSSSLAQFLNDDAEVTQVLNDSEMRGVYLKSVRSPALGSRYRMVHREFNSTEIFSQIPEQDEAYAEDSFCVAEGDEETCNKSESSEEEEVCVNFDLLNNESFGGGGGRYLTRRRKKLHGANMEQNCSAPVQKKPSRIIVLSDSSGEETNVSNEKGTAAHCSRAGRENAELLTSMPSVSSVPHKKSAGDVSAHQSAESKSGMLLGLKASVSEVLDFHPGPRSGSGKEALQAAAQHLQLESSVKNSAGNAPGATKASPALLDGDTALCVLVDSREISSGADVISSLKAVHGLKVQVCSLGSGDYVVSNRMAVERKFQSELLSSVNRTKVTQRLQRLQGMFERVCVIVEKDRTRPGETSRFSQRTQHYDATLAALLQAGIRVLFSSCQEETAVLLKELALLEQRKNAAICVPTEVEGHKQEMLNFYLSLPNISYLAALNMCHHFSSVRTMVNSSPSDIAAGARVSLQRAEETYRYLRYGFDTQMLPESLCAKGKSNTATRS", "length": 2041, "header": "sp|A0A1D5PRR9-1|FANCM_CHICK Isoform 1 of Fanconi anemia group M protein OS=Gallus gallus OX=9031 GN=FANCM PE=1 SV=1 CANONICAL=A0A1D5PRR9-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PRR9-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRR9/entry#A0A1D5PRR9-1", "sequence": { "sequence": "MSGGRQRTLPEAWRRAAGPALQAGRDADGNDDDDDELLAAAAAELDPDPNPNVDPNPGPGPEAAAGGFCAAAGALWIYPTNRPERPYQLRMARAALFANTLLCLPTGLGKTFVAAVVMYNFYRWFPSGKVLFLAPTKALVAQQMEACAQLMGIPGRDMAEMTGGTQALSRRELWASRRVFFLTPQIMVNDLSRGTCPAVEVKCLVVDEAHKALGNHAYCQVVKELSRYTTQFRVLALTATPGSDTKAVQQVVSNLLIAQIELCSEDSPEIQPYSHERQVEKIVVPLGEELGGIQRAYIHVLETFAGRLIKLGVLARRDVPSLTKYQIILARDQYRKNPSPQNVGMQPGIIEGDFALCISLYHGYELLQQMGVRSLFIYLCGIMDGSKGLTRTKNELGRNEDFMRLYQQLTDMFSDTCQTSANGNLHKSRTVSENKKEFIYSHPKLKKLEEIVIEHFKSRKMGCSDQTTSGGTCVDTRVMIFSSFRDSVQEIAEMLSRFSPVVRVMTFVGHSTGKSTKGFTQKEQLEVVKRFREGGYNTLVSTCVGEEGLDIGEVDLIICFDAQKSPIRLVQRMGRTGRQRQGRVVVILAEGREERTYNQSQSNRRSIQKAISGNKMLHFYQHSPRMIPEGINPELHRMFITAEKYKPNDSGRLPKGRPSSLHHKSALFSCVTDPKEMHCHENWSLSPEEFEIWDRLYRLKENDGVKEPILPHTRFETLENLDKTSKPEEEAAHKLSLSEWSIWQSRPFPTSMVDHSDRCYHFISVMELIEVMRQEQGDCSYELELQPHLRIEDIHVRRNKGHLSTTSSAFAQKTHSSKRDMARTKRPFVPDVNDNEREFFSIFKTTNTKTPRTAPGLDLEEPELPTDTNGSEPCSARRLTLVASTDQGSPKEEEIEKVTFDLNEFNDLCDDGESTVAHESAAVKDLRLLDKHCSSVGLNHTDLGYSSFTAEKSPASSDLFYLPESHVDSFVLVSSSAELAGLEGAFSCVKGLLAHSPPPVSKLEGIEELLRHEETLCPLPKVSCRSYSGQLPHGDFPSSLAVDQSLLPAESPELEVTIGLSAAVNTCVSKPASTPTAAGGAEERPPGGGSFHSLLGKEGFTANHTDNPPNKHFVQGDEEDSEMKRDVTIDGEKSIHLFEDEHTYKVNDEMPSVDVEPLLRLGSGGHTARPSAGPASQQPPSGDSPRGDTACGEGAARGEMAPGGAWGRGSAAEQALHNSELCDYSQELFSVNFDLGFSIEECEEEIFEGDTDAMNTPKLNSASRSRADVQLTANRKSLNDGCRVQTPPKWDCKGLKGRNISTPLPLQSGHVRDTAVPGGTAGGRTGRGSPGASPPSPATPTGRRVSSAEATRRIRKKVFSTVREETPEVCPTDKVNPNSQRNSFGSSASDALHTTGGRTENLEGTNLHTSRVFPAEGTSSESEEEIVFQRKNRRNNVLRSPDVGSDSDFGSPVCAVRKRRHPLTVSDVSSDDGVDFHKNPNRGTRGCSAAGSKAQLRGVKRQKVRSKVTCKNAARQFLDEEAELSQQDESCVSSDETEDTDKELSSSLAQFLNDDAEVTQVLNDSEMRGVYLKSVRSPALGSRYRMVHREFNSTEIFSQIPEQDEAYAEDSFCVAEGDEETCNKSESSEEEEVCVNFDLLNNESFGGGGGRYLTRRRKKLHGANMEQNCSAPVQKKPSRIIVLSDSSGEETNVSNEKGTAAHCSRAGRENAELLTSMPSVSSVPHKKSAGDVSAHQSAESKSGMLLGLKASVSEVLDFHPGPRSGSGKEALQAAAQHLQLESSVKNSAGNAPGATKASPALLDGDTALCVLVDSREISSGADVISSLKAVHGLKVQVCSLGSGDYVVSNRMAVERKFQSELLSSVNRTKVTQRLQRLQGMFERVCVIVEKDRTRPGETSRFSQRTQHYDATLAALLQAGIRVLFSSCQEETAVLLKELALLEQRKNAAICVPTEVEGHKQEMLNFYLSLPNISYLAALNMCHHFSSVRTMVNSSPSDIAAGARVSLQRAEETYRYLRYGFDTQMLPESLCAKGKSNTATRS", "length": 2041, "header": "sp|A0A1D5PRR9-1|FANCM_CHICK Isoform 1 of Fanconi anemia group M protein OS=Gallus gallus OX=9031 GN=FANCM PE=1 SV=1 CANONICAL=A0A1D5PRR9-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1339, "start_aa": "Thr", "end_pos": 1339, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1339", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 240, "start_aa": "Thr", "end_pos": 240, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr240", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "Sequence and comparative analysis of the chicken genome provide unique perspectives on vertebrate evolution.", "journal": "Nature", "date": "2004", "authors": "", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PRR9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRR9" } ], "reference": [ { "type": "PubMed", "id": "15592404", "url": "https://glygen.org/publication/PubMed/15592404" } ] }, { "title": "The vertebrate Hef ortholog is a component of the Fanconi anemia tumor-suppressor pathway.", "journal": "Nature structural & molecular biology", "date": "2005", "authors": "Mosedale G, Niedzwiedz W, Alpi A, Perrina F, Pereira-Leal JB, Johnson M, Langevin F, Pace P, Patel KJ", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PRR9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRR9" } ], "reference": [ { "type": "PubMed", "id": "16116434", "url": "https://glygen.org/publication/PubMed/16116434" } ] }, { "title": "The Walker B motif in avian FANCM is required to limit sister chromatid exchanges but is dispensable for DNA crosslink repair.", "journal": "Nucleic acids research", "date": "2009-07", "authors": "Rosado Ivan V, Niedzwiedz Wojciech, Alpi Arno F, Patel Ketan J", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PRR9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRR9" } ], "reference": [ { "type": "PubMed", "id": "19465393", "url": "https://glygen.org/publication/PubMed/19465393" } ] } ], "pathway": [ { "id": "gga:100857997", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100857997", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "3'-5' DNA helicase activity", "id": "GO:0043138", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043138", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PRR9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRR9" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PRR9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRR9" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PRR9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRR9" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PRR9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRR9" } ], "pmid": "" }, { "name": "RNA helicase activity", "id": "GO:0003724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003724", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PRR9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRR9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PRR9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRR9" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PRR9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRR9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PRR9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRR9" } ], "pmid": "" }, { "name": "homologous recombination", "id": "GO:0035825", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035825", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PRR9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRR9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1103, "end_pos": 1105, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1299, "end_pos": 1301, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1563, "end_pos": 1565, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1592, "end_pos": 1594, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1623, "end_pos": 1625, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1642, "end_pos": 1644, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1668, "end_pos": 1670, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1692, "end_pos": 1694, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1866, "end_pos": 1868, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1971, "end_pos": 1973, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1992, "end_pos": 1994, "annotation": "n_glycosylation_sequon" }, { "start_pos": 598, "end_pos": 600, "annotation": "n_glycosylation_sequon" }, { "start_pos": 648, "end_pos": 650, "annotation": "n_glycosylation_sequon" }, { "start_pos": 682, "end_pos": 684, "annotation": "n_glycosylation_sequon" }, { "start_pos": 869, "end_pos": 871, "annotation": "n_glycosylation_sequon" }, { "start_pos": 939, "end_pos": 941, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [ { "annotation": "Phosphorylated; hyperphosphorylated in response to genotoxic stress.", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PRR9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRR9" }, { "database": "PubMed", "id": "19465393", "url": "https://glygen.org/publication/PubMed/19465393" } ] } ], "interactions": [], "reactions": [ { "id": "13065", "name": "", "equation": "ATP + H2O = ADP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZC95-1", "A0A1D5PHB6-1", "A0A8V0XJV9-1", "A0A8V0ZFN9-1", "A0A1D5PIN7-1", "A0A8V0XT73-1", "A0A8V0XZB8-1", "A0A8V1AJ43-1", "A0A8V0ZU49-1", "P53478-1", "Q5F485-1", "Q5ZHZ0-1", "Q5ZI74-1", "Q5ZIW1-1", "Q5ZKB9-1", "Q5ZM36-1", "Q5ZMN2-1", "A0A8V0XLC7-1", "F1NFJ0-1", "A0A8V0YT68-1", "A0A1D5NTY5-1", "A0A8V0YU49-1", "A0A8V0YHC8-1", "A0A8V0ZPN6-1", "Q5ZJF6-1", "Q5ZKB7-1", "Q8JFP1-1", "A0A8V0YUW3-1", "Q5ZLN8-1", "E1BY42-1", "F1N8Z4-1", "F1NHI3-1", "A0A8V0XI26-1", "A0A8V0XEC4-1", "A0A8V0Y1J8-1", "A0A8V0Y242-1", "A0A8V0X9Z6-1", "A0A8V0Z289-1", "A0A8V0YFB8-1", "A0A8V0YFG2-1", "A0A8V0YNF9-1", "F1N991-1", "A0A8V0ZZF5-1", "A0A8V1ACD8-1", "A0A8V0ZUT3-1", "A0A8V0ZNU6-1", "A0A1D5P5I0-1", "A0A8V0ZZK3-1", "A0A8V1A3M1-1", "A0A8V1AJY9-1", "A0A8V1A712-1", "A0A8V1A7M6-1", "A0A3S5ZPN3-1", "A0A8V1A4V3-1", "A0A8V1AER6-1", "A0A8V1AL41-1", "A0A8V1A5D6-1", "A0A1D5PRR9-1", "A0A8V0Y0A4-1", "Q5ZKK7-1", "A0A8V1AFG8-1", "A0A8V0ZWH7-1", "A0A8V0YLM0-1", "A0A8V0ZNW3-1", "F1ND48-1", "F1NQJ3-1", "P08023-1", "P60706-1", "P63270-1", "P68034-1", "P68139-1", "Q5ZJT0-1", "Q5ZMQ2-1", "Q90593-1", "Q92058-1", "Q9I920-1", "Q90WU3-1", "A0A8V0ZVY2-1", "A0A8V0ZPM1-1", "Q3YK19-1", "E1BSC0-1", "A0A8V0X9Y7-1", "Q5ZM98-1", "F1NZ23-1", "A0A8V0YUG9-1", "F1NN44-1", "P08110-1", "F1NTD6-1", "A0A8V0Z655-1", "A0A8V1ALH0-1", "B6ZLK2-1", "A0A8V0YLC1-1", "Q06A37-1", "A0A8V0YGQ1-1", "A0A1D5PD32-1", "Q6EE31-1", "A0A8V0XX13-1", "A0A8V0YCY8-1", "A0A8V0Z5P2-1", "A0A8V0ZUQ0-1", "A0A8V1ADZ7-1", "A0A8V0XG98-1", "A0A8V0ZR10-1", "A0A8V1AFJ9-1", "Q5ZJ54-1", "Q5ZJK8-1", "A0A8V0Y005-1", "A0A8V0YAA4-1", "A0A8V0XGV3-1", "A0A8V0X600-1", "Q5ZM73-1", "Q5ZM83-1", "A0A8V0ZUR5-1", "A0A8V0ZE45-1", "A0A8V0ZEN5-1", "F1NA92-1", "A0A8V0ZTR5-1", "A0A8V1A7P4-1", "A0A8V1AIK2-1", "F1P5C0-1", "A0A8V0XHD1-1", "A0A8V0X655-1", "A0A8V0XMP8-1", "A0A8V0YUC5-1", "A0A8V0Z1F9-1", "A0A8V0Z659-1", "A0A8V0YRH6-1", "A0A8V0ZS56-1", "I0IUP3-1", "I0IUP4-1", "O93257-1", "O93295-1", "A0A8V0ZIP8-1", "Q9DG67-1", "P37383-1", "Q5ZKG3-1", "P79784-1", "A0A1D5PS27-1", "A0A1D5PVS9-1", "A0A8V1AE46-1", "A0A8V1A8Y2-1", "A0A8V1AKU6-1", "O12944-1", "A0A8V0YQS3-1", "A0A8V0Z2M8-1" ], "evidence": [ { "id": "13065", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/13065" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5NTY5", "gene_name": "LOC430766", "activity": [ { "ec_number": "3.6.4.6", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5NTY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NTY5" } ] }, { "ec_number": "3.6.4.6", "activity": "", "evidence": [ { "id": "A0A1D5NTY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NTY5" } ] } ] }, { "uniprot_ac": "A0A1D5P5I0", "gene_name": "IFIH1", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5P5I0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P5I0" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A1D5P5I0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P5I0" } ] } ] }, { "uniprot_ac": "A0A1D5PD32", "gene_name": "DDX17", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5PD32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PD32" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A1D5PD32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PD32" } ] } ] }, { "uniprot_ac": "A0A1D5PHB6", "gene_name": "DHX36", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5PHB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PHB6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A1D5PHB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PHB6" } ] } ] }, { "uniprot_ac": "A0A1D5PIN7", "gene_name": "DHX30", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5PIN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PIN7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A1D5PIN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PIN7" } ] } ] }, { "uniprot_ac": "A0A1D5PRR9", "gene_name": "FANCM", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5PRR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRR9" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A1D5PRR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRR9" } ] } ] }, { "uniprot_ac": "A0A1D5PS27", "gene_name": "ENTPD2", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "A0A1D5PS27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PS27" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "A0A1D5PS27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PS27" } ] } ] }, { "uniprot_ac": "A0A1D5PVS9", "gene_name": "ENTPD3", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "A0A1D5PVS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PVS9" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "A0A1D5PVS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PVS9" } ] } ] }, { "uniprot_ac": "A0A3S5ZPN3", "gene_name": "DDX5", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3S5ZPN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPN3" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A3S5ZPN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPN3" } ] } ] }, { "uniprot_ac": "A0A8V0X600", "gene_name": "DDX43", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0X600", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X600" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0X600", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X600" } ] } ] }, { "uniprot_ac": "A0A8V0X655", "gene_name": "DHX32", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0X655", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X655" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0X655", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X655" } ] } ] }, { "uniprot_ac": "A0A8V0X9Y7", "gene_name": "CFTR", "activity": [ { "ec_number": "5.6.1.6", "activity": "ATP + H2O + closed Cl(-) channel = ADP + phosphate + open Cl(-) channel.", "evidence": [ { "id": "A0A8V0X9Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X9Y7" } ] }, { "ec_number": "5.6.1.6", "activity": "", "evidence": [ { "id": "A0A8V0X9Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X9Y7" } ] } ] }, { "uniprot_ac": "A0A8V0X9Z6", "gene_name": "MOV10L1", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0X9Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X9Z6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0X9Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X9Z6" } ] } ] }, { "uniprot_ac": "A0A8V0XEC4", "gene_name": "DDX10", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XEC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEC4" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0XEC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEC4" } ] } ] }, { "uniprot_ac": "A0A8V0XG98", "gene_name": "HELQ", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XG98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XG98" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A8V0XG98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XG98" } ] } ] }, { "uniprot_ac": "A0A8V0XGV3", "gene_name": "DDX3X", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XGV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XGV3" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0XGV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XGV3" } ] } ] }, { "uniprot_ac": "A0A8V0XHD1", "gene_name": "AQR", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XHD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XHD1" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0XHD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XHD1" } ] } ] }, { "uniprot_ac": "A0A8V0XI26", "gene_name": "DDX1", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XI26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XI26" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0XI26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XI26" } ] } ] }, { "uniprot_ac": "A0A8V0XJV9", "gene_name": "SPATA5", "activity": [ { "ec_number": "3.6.4.6", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XJV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJV9" } ] }, { "ec_number": "3.6.4.6", "activity": "", "evidence": [ { "id": "A0A8V0XJV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJV9" } ] }, { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XJV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJV9" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "A0A8V0XJV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJV9" } ] } ] }, { "uniprot_ac": "A0A8V0XLC7", "gene_name": "MCM4", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XLC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLC7" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0A8V0XLC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLC7" } ] } ] }, { "uniprot_ac": "A0A8V0XMP8", "gene_name": "ZGRF1", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "A0A8V0XMP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMP8" } ] }, { "ec_number": "5.6.2.3", "activity": "", "evidence": [ { "id": "A0A8V0XMP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMP8" } ] } ] }, { "uniprot_ac": "A0A8V0XT73", "gene_name": "FBXO18", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XT73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XT73" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A8V0XT73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XT73" } ] } ] }, { "uniprot_ac": "A0A8V0XX13", "gene_name": "LOC101748706", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XX13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XX13" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A8V0XX13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XX13" } ] } ] }, { "uniprot_ac": "A0A8V0XZB8", "gene_name": "DHX34", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XZB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XZB8" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0XZB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XZB8" } ] } ] }, { "uniprot_ac": "A0A8V0Y005", "gene_name": "HSPA9", "activity": [ { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0Y005", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y005" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "A0A8V0Y005", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y005" } ] } ] }, { "uniprot_ac": "A0A8V0Y0A4", "gene_name": "AK6", "activity": [ { "ec_number": "2.7.4.3", "activity": "AMP + ATP = 2 ADP.", "evidence": [ { "id": "A0A8V0Y0A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y0A4" } ] }, { "ec_number": "2.7.4.3", "activity": "", "evidence": [ { "id": "A0A8V0Y0A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y0A4" } ] } ] }, { "uniprot_ac": "A0A8V0Y1J8", "gene_name": "YTHDC2", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0Y1J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y1J8" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0Y1J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y1J8" } ] } ] }, { "uniprot_ac": "A0A8V0Y242", "gene_name": "DDX41", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0Y242", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y242" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0Y242", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y242" } ] } ] }, { "uniprot_ac": "A0A8V0YAA4", "gene_name": "XRCC6", "activity": [ { "ec_number": "4.2.99.18", "activity": "2'-deoxyribonucleotide-(2'-deoxyribose 5'-phosphate)-2'-deoxyribonucleotide-DNA = a 3'-end 2'-deoxyribonucleotide-(2,3-dehydro-2,3-deoxyribose 5'-phosphate)-DNA + a 5'-end 5'-phospho-2'-deoxyribonucleoside-DNA + H(+).", "evidence": [ { "id": "A0A8V0YAA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAA4" } ] }, { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YAA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAA4" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A8V0YAA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAA4" } ] }, { "ec_number": "4.2.99.18", "activity": "", "evidence": [ { "id": "A0A8V0YAA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAA4" } ] } ] }, { "uniprot_ac": "A0A8V0YCY8", "gene_name": "RIOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YCY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YCY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY8" } ] } ] }, { "uniprot_ac": "A0A8V0YFB8", "gene_name": "ATP13A4", "activity": [ { "ec_number": "7.2.2.-", "activity": "", "evidence": [ { "id": "A0A8V0YFB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFB8" } ] } ] }, { "uniprot_ac": "A0A8V0YFG2", "gene_name": "ATP13A5", "activity": [ { "ec_number": "7.2.2.-", "activity": "", "evidence": [ { "id": "A0A8V0YFG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFG2" } ] } ] }, { "uniprot_ac": "A0A8V0YGQ1", "gene_name": "DDX59", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YGQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGQ1" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0YGQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGQ1" } ] } ] }, { "uniprot_ac": "A0A8V0YHC8", "gene_name": "VCP", "activity": [ { "ec_number": "3.6.4.6", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YHC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHC8" } ] }, { "ec_number": "3.6.4.6", "activity": "", "evidence": [ { "id": "A0A8V0YHC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHC8" } ] } ] }, { "uniprot_ac": "A0A8V0YLC1", "gene_name": "DDX11", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "A0A8V0YLC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLC1" } ] }, { "ec_number": "5.6.2.3", "activity": "", "evidence": [ { "id": "A0A8V0YLC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLC1" } ] } ] }, { "uniprot_ac": "A0A8V0YLM0", "gene_name": "RECQL", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YLM0", "database": 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"id": "A0A8V0YQS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQS3" } ] } ] }, { "uniprot_ac": "A0A8V0YRH6", "gene_name": "ERCC6L", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YRH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRH6" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0A8V0YRH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRH6" } ] } ] }, { "uniprot_ac": "A0A8V0YT68", "gene_name": "ATRX", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YT68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YT68" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0A8V0YT68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YT68" } ] } ] }, { "uniprot_ac": "A0A8V0YU49", "gene_name": "DHX29", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YU49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YU49" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0YU49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YU49" } ] } ] }, { "uniprot_ac": "A0A8V0YUC5", "gene_name": "SKIV2L2", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YUC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUC5" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0YUC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUC5" } ] } ] }, { "uniprot_ac": "A0A8V0YUG9", "gene_name": "TDRD9", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YUG9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUG9" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0YUG9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUG9" } ] } ] }, { "uniprot_ac": "A0A8V0YUW3", "gene_name": "EIF4A2", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YUW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUW3" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0YUW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUW3" } ] } ] }, { "uniprot_ac": "A0A8V0Z1F9", "gene_name": "DHX57", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0Z1F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1F9" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0Z1F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1F9" } ] } ] }, { "uniprot_ac": "A0A8V0Z289", "gene_name": "DDX24", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0Z289", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z289" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0Z289", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z289" } ] } ] }, { "uniprot_ac": "A0A8V0Z2M8", "gene_name": "MCM8", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0Z2M8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2M8" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A8V0Z2M8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2M8" } ] } ] }, { "uniprot_ac": "A0A8V0Z5P2", "gene_name": "RHOT2", "activity": [ { "ec_number": "3.6.5.-", "activity": "", "evidence": [ { "id": "A0A8V0Z5P2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5P2" } ] } ] }, { "uniprot_ac": "A0A8V0Z655", "gene_name": "SNRNP200", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0Z655", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z655" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0Z655", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z655" } ] } ] }, { "uniprot_ac": "A0A8V0Z659", "gene_name": "TWNK", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "A0A8V0Z659", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z659" } ] }, { "ec_number": "5.6.2.3", "activity": "", "evidence": [ { "id": "A0A8V0Z659", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z659" } ] } ] }, { "uniprot_ac": "A0A8V0ZC95", "gene_name": "MCM6", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZC95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC95" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0A8V0ZC95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC95" } ] } ] }, { "uniprot_ac": "A0A8V0ZE45", "gene_name": "DDX42", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZE45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE45" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0ZE45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE45" } ] } ] }, { "uniprot_ac": "A0A8V0ZEN5", "gene_name": "DDX19", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZEN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEN5" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0ZEN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEN5" } ] } ] }, { "uniprot_ac": "A0A8V0ZFN9", "gene_name": "DDX54", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZFN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFN9" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0ZFN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFN9" } ] } ] }, { "uniprot_ac": "A0A8V0ZIP8", "gene_name": "XRCC5", "activity": [ { "ec_number": "4.2.99.18", "activity": "2'-deoxyribonucleotide-(2'-deoxyribose 5'-phosphate)-2'-deoxyribonucleotide-DNA = a 3'-end 2'-deoxyribonucleotide-(2,3-dehydro-2,3-deoxyribose 5'-phosphate)-DNA + a 5'-end 5'-phospho-2'-deoxyribonucleoside-DNA + H(+).", "evidence": [ { "id": "A0A8V0ZIP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIP8" } ] }, { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZIP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIP8" } ] }, { "ec_number": "4.2.99.18", "activity": "", "evidence": [ { "id": "A0A8V0ZIP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIP8" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A8V0ZIP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIP8" } ] } ] }, { "uniprot_ac": "A0A8V0ZNU6", "gene_name": "DDX18", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZNU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNU6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0ZNU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNU6" } ] } ] }, { "uniprot_ac": "A0A8V0ZNW3", "gene_name": "ENTPD1", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "A0A8V0ZNW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNW3" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "A0A8V0ZNW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNW3" } ] } ] }, { "uniprot_ac": "A0A8V0ZPM1", "gene_name": "LOC121108097", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZPM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPM1" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0ZPM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPM1" } ] } ] }, { "uniprot_ac": "A0A8V0ZPN6", "gene_name": "INO80", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "A0A8V0ZPN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPN6" } ] } ] }, { "uniprot_ac": "A0A8V0ZR10", "gene_name": "PIF1", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "A0A8V0ZR10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR10" } ] }, { "ec_number": "5.6.2.3", "activity": "", "evidence": [ { "id": "A0A8V0ZR10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR10" } ] } ] }, { "uniprot_ac": "A0A8V0ZS56", "gene_name": "HFM1", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZS56", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS56" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A8V0ZS56", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS56" } ] } ] }, { "uniprot_ac": "A0A8V0ZTR5", "gene_name": "LOC423693", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZTR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTR5" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0ZTR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTR5" } ] } ] }, { "uniprot_ac": "A0A8V0ZU49", "gene_name": "DNA2", "activity": [ { "ec_number": "3.1.-.-", "activity": "", "evidence": [ { "id": "A0A8V0ZU49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU49" } ] }, { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZU49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU49" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0A8V0ZU49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU49" } ] } ] }, { "uniprot_ac": "A0A8V0ZUQ0", "gene_name": "DDX21", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZUQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUQ0" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0ZUQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUQ0" } ] } ] }, { "uniprot_ac": "A0A8V0ZUR5", "gene_name": "DDX6", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZUR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUR5" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0ZUR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUR5" } ] } ] }, { "uniprot_ac": "A0A8V0ZUT3", "gene_name": "DHX58", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZUT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUT3" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0ZUT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUT3" } ] } ] }, { "uniprot_ac": "A0A8V0ZVY2", "gene_name": "RTEL1", "activity": [ { "ec_number": "5.6.2.-", "activity": "", "evidence": [ { "id": "A0A8V0ZVY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVY2" } ] } ] }, { "uniprot_ac": "A0A8V0ZWH7", "gene_name": "DHX35", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZWH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWH7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0ZWH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWH7" } ] } ] }, { "uniprot_ac": "A0A8V0ZZF5", "gene_name": "DHX8", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZZF5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZF5" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0ZZF5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZF5" } ] } ] }, { "uniprot_ac": "A0A8V0ZZK3", "gene_name": "SUPV3L1", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZZK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZK3" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0ZZK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZK3" } ] } ] }, { "uniprot_ac": "A0A8V1A3M1", "gene_name": "DDX55", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1A3M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3M1" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V1A3M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3M1" } ] } ] }, { "uniprot_ac": "A0A8V1A4V3", "gene_name": "POLQ", "activity": [ { "ec_number": "2.7.7.7", "activity": "DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate.", "evidence": [ { "id": "A0A8V1A4V3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V3" } ] }, { "ec_number": "2.7.7.49", "activity": "DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate.", "evidence": [ { "id": "A0A8V1A4V3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V3" } ] }, { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1A4V3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V3" } ] }, { "ec_number": "2.7.7.7", "activity": "", "evidence": [ { "id": "A0A8V1A4V3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V3" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0A8V1A4V3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V3" } ] }, { "ec_number": "2.7.7.49", "activity": "", "evidence": [ { "id": "A0A8V1A4V3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V3" } ] } ] }, { "uniprot_ac": "A0A8V1A5D6", "gene_name": "DDX51", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1A5D6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5D6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V1A5D6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5D6" } ] } ] }, { "uniprot_ac": "A0A8V1A712", "gene_name": "", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1A712", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A712" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V1A712", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A712" } ] } ] }, { "uniprot_ac": "A0A8V1A7M6", "gene_name": "", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1A7M6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V1A7M6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M6" } ] } ] }, { "uniprot_ac": "A0A8V1A7P4", "gene_name": "DDX49", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1A7P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P4" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V1A7P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P4" } ] } ] }, { "uniprot_ac": "A0A8V1A8Y2", "gene_name": "ENTPD8", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "A0A8V1A8Y2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8Y2" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "A0A8V1A8Y2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8Y2" } ] } ] }, { "uniprot_ac": "A0A8V1ACD8", "gene_name": "NSF", "activity": [ { "ec_number": "3.6.4.6", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1ACD8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACD8" } ] }, { "ec_number": "3.6.4.6", "activity": "", "evidence": [ { "id": "A0A8V1ACD8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACD8" } ] } ] }, { "uniprot_ac": "A0A8V1ADZ7", "gene_name": "RHOT1", "activity": [ { "ec_number": "3.6.5.-", "activity": "", "evidence": [ { "id": "A0A8V1ADZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADZ7" } ] } ] }, { "uniprot_ac": "A0A8V1AE46", "gene_name": "ENTPD8L1", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "A0A8V1AE46", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE46" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "A0A8V1AE46", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE46" } ] } ] }, { "uniprot_ac": "A0A8V1AER6", "gene_name": "MOV10", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1AER6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AER6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V1AER6", "database": "UniProtKB", "url": 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"ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1AIK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIK2" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V1AIK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIK2" } ] } ] }, { "uniprot_ac": "A0A8V1AJ43", "gene_name": "DHX40", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1AJ43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ43" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V1AJ43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ43" } ] } ] }, { "uniprot_ac": "A0A8V1AJY9", "gene_name": "DDX31", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1AJY9", "database": 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"424890", "url": "https://www.ncbi.nlm.nih.gov/gene/424890", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001478", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001478", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004172", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004172", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008144", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008144", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008145", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008145", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015143", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015143", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016313", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016313", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019583", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019583", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019590", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019590", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020590", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020590", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036028", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036028", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036034", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036034", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036892", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036892", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050614", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050614", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:424890", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424890", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A1D5PT29", "url": "https://www.orthodb.org/?gene=A0A1D5PT29", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2TXA3", "url": "https://www.orthodb.org/?gene=A0A3Q2TXA3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2U359", "url": "https://www.orthodb.org/?gene=A0A3Q2U359", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YTU2", "url": "https://www.orthodb.org/?gene=A0A8V0YTU2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YTV1", "url": "https://www.orthodb.org/?gene=A0A8V0YTV1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z0M5", "url": "https://www.orthodb.org/?gene=A0A8V0Z0M5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z7P0", "url": "https://www.orthodb.org/?gene=A0A8V0Z7P0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z7R0", "url": "https://www.orthodb.org/?gene=A0A8V0Z7R0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BT38", "url": "https://www.orthodb.org/?gene=E1BT38", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23119", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23119", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23119:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23119:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00018", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00018", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00595", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00595", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00625", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00625", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF09058", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09058", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF10600", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10600", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF10608", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10608", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-438066", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-438066", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5673001", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5673001", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-8849932", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8849932", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_025009380", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025009380", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PT29", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PT29", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PT29-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PT29-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2TXA3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TXA3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2TXA3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TXA3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2U359", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U359", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2U359-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U359-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YTU2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTU2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YTU2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTU2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YTV1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTV1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YTV1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTV1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z0M5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0M5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z0M5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0M5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z7P0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7P0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z7P0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7P0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z7R0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7R0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z7R0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7R0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BT38", "url": "https://www.uniprot.org/uniprotkb/E1BT38", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BT38-1", "url": "https://www.uniprot.org/uniprotkb/E1BT38-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPVRKQDTQRALRLLQEYRSKLSQAEDRQLRNSIERVIGIFQSNLFQALIDIQEFYEVTLLDNPKCIDHSQPSEPIQPVNTWDFSSLPSTTVTSETLPSSLSPSVEKYRYQDEDTPPQEHSSPHIANEVTGPELVHVSEKNLSQIENVHGFVSHSHISPVKPTEAVPSSSPIVPVIPVPPVPAETTVIPSTIPQANPPPVLVNTDSLDTPTYVNGTDADYEYEEITLERGNSGLGFSIAGGTDNPHIGDDSSIFITKIIAGGAAAQDGRLRVNDCILRVNEVDVRDVTHSKAVEALKEAGSIVRLYVKRRKPVTEKIVEIKLVKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGKLQIGDKLLAVNSVCLEEVTHEEAVTALKNTSDFVYLKVAKPTSMFMNDSYAPPDITNSYSQPVDNHITPSAYLGQSLPPASPGRYSPIPKGMLGDDEITREPRKVVLHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDRIISVNGVDLKAATHEQAATALKNAGQAVTIVAQYRPEEYSRFEAKIHDLREQMMNSSISSGSGSLRTSQKRSLYVRALFDYDKTKDSGLPSQGLNFKFGDILHVINASDDEWWQARQVTPDGESDEIGVIPSKRRVEKKERARLKTVKFNSKTRGEKGQSFNDKRKKNLFSRKFPFYKNKDQSEQETSDIDRGQEEYVLSYEQVNQQEVNYTRPVIVLGPMKDRINDDLISEFPDKFGSCVPHTTRPKRDYEVDGRDYHFVTSREQMEKDIQEHKFIEAGQYNNHLYGTSVQSVREVAEKGKHCILDVSGNAIKRLQIAQLYPISIFIKPKTVENIMEMNKRLTEEQARKTFERAMKLEQEFTEHFTAIIQGDTLEEIYNQVKQIIEEQSGPYIWVPAKEKL", "length": 915, "header": "tr|A0A3Q2U359-1|A0A3Q2U359_CHICK Isoform 1 of Disks large homolog 1 OS=Gallus gallus OX=9031 GN=DLG1 PE=1 SV=1 CANONICAL=A0A3Q2U359-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PT29-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U359/entry#A0A1D5PT29-1", "sequence": { "sequence": "MPVRKQDTQRALRLLQEYRSKLSQAEDRQLRNSIERVIGIFQSNLFQALIDIQEFYEVTLLDNPKCIDHSQPSEPIQPVNTWDFSSLPSTTVTSETLPSSLSPSVEKYRYQDEDTPPQEHSSPHIANEVTGPELVHVSEKNLSQIENVHGFVSHSHISPVKPTEAVPSSSPIVPVIPVPPVPAETTVIPSTIPQANPPPVLVNTDSLDTPTYVNGTDADYEYEEITLERGNSGLGFSIAGGTDNPHIGDDSSIFITKIIAGGAAAQDGRLRVNDCILRVNEVDVRDVTHSKAVEALKEAGSIVRLYVKRRKPVTEKIVEIKLVKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGKLQIGDKLLAVNSVCLEEVTHEEAVTALKNTSDFVYLKVAKPTSMFMNDSYAPPDITNSYSQPVDNHITPSAYLGQSLPPASPGRYSPIPKGMLGDDEITREPRKVVLHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDRIISVNGVDLKAATHEQAATALKNAGQAVTIVAQYRPEEYSRFEAKIHDLREQMMNSSISSGSGSLRTSQKRSLYVRALFDYDKTKDSGLPSQGLNFKFGDILHVINASDDEWWQARQVTPDGESDEIGVIPSKRRVEKKERARLKTVKFNSKTRGEKGEVPDDMGSKGLKHVTSNASDSESSYRGQEEYVLSYEQVNQQEVNYTRPVIVLGPMKDRINDDLISEFPDKFGSCVPHTTRPKRDYEVDGRDYHFVTSREQMEKDIQEHKFIEAGQYNNHLYGTSVQSVREVAEKGKHCILDVSGNAIKRLQIAQLYPISIFIKPKTVENIMEMNKRLTEEQARKTFERAMKLEQEFTEHFTAIIQGDTLEEIYNQVKQIIEEQSGPYIWVPAKEKL", "length": 907, "header": "tr|A0A1D5PT29-1|A0A3Q2U359_CHICK Computationally mapped isoform of Disks large homolog 1 OS=Gallus gallus OX=9031 GN=DLG1 PE=1 SV=1 CANONICAL=A0A3Q2U359-1" }, "locus": { "chromosome": "9", "start_pos": 12296452, "end_pos": 12166258, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010041857.1", "url": "https://www.ensembl.org/id/ENSGALT00010041857.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024483.1", "url": "https://www.ensembl.org/id/ENSGALP00010024483.1" } ] } }, { "isoform_ac": "A0A3Q2TXA3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U359/entry#A0A3Q2TXA3-1", "sequence": { "sequence": "MPVRKQDTQRALRLLQEYRSKLSQAEDRQLRNSIERVIGIFQSNLFQALIDIQEFYEVTLLDNPKCIDHSQPSEPIQPVNTWDFSSLPSTTVTSETLPSSLSPSVEKYRYQDEDTPPQEHSSPHIANEVTGPELVHVSEKNLSQIENVHGFVSHSHISPVKPTEAVPSSSPIVPVIPVPPVPAETTVIPSTIPQANPPPVLVNTDSLDTPTYVNGTDADYEYEEITLERGNSGLGFSIAGGTDNPHIGDDSSIFITKIIAGGAAAQDGRLRVNDCILRVNEVDVRDVTHSKAVEALKEAGSIVRLYVKRRKPVTEKIVEIKLVKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGKLQIGDKLLAVNSVCLEEVTHEEAVTALKNTSDFVYLKVAKPTSMFMNDSYAPPDITNSYSQPVDNHITPSAYLGQSLPPASPGRYSPIPKGMLGDDEITREPRKVVLHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDRIISVNGVDLKAATHEQAATALKNAGQAVTIVAQYRPEEYSRFEAKIHDLREQMMNSSISSGSGSLRTSQKRSLYVRALFDYDKTKDSGLPSQGLNFKFGDILHVINASDDEWWQARQVTPDGESDEIGVIPSKRRVEKKERARLKTVKFNSKTRGEKGEVPDDMGSKGLSGQEEYVLSYEQVNQQEVNYTRPVIVLGPMKDRINDDLISEFPDKFGSCVPHTTRPKRDYEVDGRDYHFVTSREQMEKDIQEHKFIEAGQYNNHLYGTSVQSVREVAEKGKHCILDVSGNAIKRLQIAQLYPISIFIKPKTVENIMEMNKRLTEEQARKTFERAMKLEQEFTEHFTAIIQGDTLEEIYNQVKQIIEEQSGPYIWVPAKEKL", "length": 893, "header": "tr|A0A3Q2TXA3-1|A0A3Q2U359_CHICK Computationally mapped isoform of Disks large homolog 1 OS=Gallus gallus OX=9031 GN=DLG1 PE=1 SV=1 CANONICAL=A0A3Q2U359-1" }, "locus": { "chromosome": "9", "start_pos": 12296452, "end_pos": 12166258, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010041872.1", "url": "https://www.ensembl.org/id/ENSGALT00010041872.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024491.1", "url": "https://www.ensembl.org/id/ENSGALP00010024491.1" } ] } }, { "isoform_ac": "A0A3Q2U359-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U359/entry#A0A3Q2U359-1", "sequence": { "sequence": "MPVRKQDTQRALRLLQEYRSKLSQAEDRQLRNSIERVIGIFQSNLFQALIDIQEFYEVTLLDNPKCIDHSQPSEPIQPVNTWDFSSLPSTTVTSETLPSSLSPSVEKYRYQDEDTPPQEHSSPHIANEVTGPELVHVSEKNLSQIENVHGFVSHSHISPVKPTEAVPSSSPIVPVIPVPPVPAETTVIPSTIPQANPPPVLVNTDSLDTPTYVNGTDADYEYEEITLERGNSGLGFSIAGGTDNPHIGDDSSIFITKIIAGGAAAQDGRLRVNDCILRVNEVDVRDVTHSKAVEALKEAGSIVRLYVKRRKPVTEKIVEIKLVKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGKLQIGDKLLAVNSVCLEEVTHEEAVTALKNTSDFVYLKVAKPTSMFMNDSYAPPDITNSYSQPVDNHITPSAYLGQSLPPASPGRYSPIPKGMLGDDEITREPRKVVLHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDRIISVNGVDLKAATHEQAATALKNAGQAVTIVAQYRPEEYSRFEAKIHDLREQMMNSSISSGSGSLRTSQKRSLYVRALFDYDKTKDSGLPSQGLNFKFGDILHVINASDDEWWQARQVTPDGESDEIGVIPSKRRVEKKERARLKTVKFNSKTRGEKGQSFNDKRKKNLFSRKFPFYKNKDQSEQETSDIDRGQEEYVLSYEQVNQQEVNYTRPVIVLGPMKDRINDDLISEFPDKFGSCVPHTTRPKRDYEVDGRDYHFVTSREQMEKDIQEHKFIEAGQYNNHLYGTSVQSVREVAEKGKHCILDVSGNAIKRLQIAQLYPISIFIKPKTVENIMEMNKRLTEEQARKTFERAMKLEQEFTEHFTAIIQGDTLEEIYNQVKQIIEEQSGPYIWVPAKEKL", "length": 915, "header": "tr|A0A3Q2U359-1|A0A3Q2U359_CHICK Isoform 1 of Disks large homolog 1 OS=Gallus gallus OX=9031 GN=DLG1 PE=1 SV=1 CANONICAL=A0A3Q2U359-1" }, "locus": { "chromosome": "9", "start_pos": 12296452, "end_pos": 12166258, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010041849.1", "url": "https://www.ensembl.org/id/ENSGALT00010041849.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024478.1", "url": "https://www.ensembl.org/id/ENSGALP00010024478.1" } ] } }, { "isoform_ac": "A0A8V0YTU2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U359/entry#A0A8V0YTU2-1", "sequence": { "sequence": "MNYIFGNNTLLYSRANRGNTGSSHSSIGPKHKQWAKKGSADELRAEPSRWQQILAFFTRRHGFIDCISVAASSTQPTEAVPSSSPIVPVIPVPPVPAETTVIPSTIPQANPPPVLVNTDSLDTPTYVNGTDADYEYEEITLERGNSGLGFSIAGGTDNPHIGDDSSIFITKIIAGGAAAQDGRLRVNDCILRVNEVDVRDVTHSKAVEALKEAGSIVRLYVKRRKPVTEKIVEIKLVKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGKLQIGDKLLAVNSVCLEEVTHEEAVTALKNTSDFVYLKVAKPTSMFMNDSYAPPDITNSYSQPVDNHITPSAYLGQSLPPASPGRYSPIPKGMLGDDEITREPRKVVLHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDRIISVNGVDLKAATHEQAATALKNAGQAVTIVAQYRPEEYSRFEAKIHDLREQMMNSSISSGSGSLRTSQKRSLYVRALFDYDKTKDSGLPSQGLNFKFGDILHVINASDDEWWQARQVTPDGESDEIGVIPSKRRVEKKERARLKTVKFNSKTRGEKGQSFNDKRKKNLFSRKFPFYKNKDQSEQETSDIDQHVTSNASDSESSYRGQEEYVLSYEQVNQQEVNYTRPVIVLGPMKDRINDDLISEFPDKFGSCVPHTTRPKRDYEVDGRDYHFVTSREQMEKDIQEHKFIEAGQYNNHLYGTSVQSVREVAEKGKHCILDVSGNAIKRLQIAQLYPISIFIKPKTVENIMEMNKRLTEEQARKTFERAMKLEQEFTEHFTAIIQGDTLEEIYNQVKQIIEEQSGPYIWVPAKEKL", "length": 843, "header": "tr|A0A8V0YTU2-1|A0A3Q2U359_CHICK Computationally mapped isoform of Disks large homolog 1 OS=Gallus gallus OX=9031 GN=DLG1 PE=1 SV=1 CANONICAL=A0A3Q2U359-1" }, "locus": { "chromosome": "9", "start_pos": 12238610, "end_pos": 12166258, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010041821.1", "url": "https://www.ensembl.org/id/ENSGALT00010041821.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024454.1", "url": "https://www.ensembl.org/id/ENSGALP00010024454.1" } ] } }, { "isoform_ac": "A0A8V0YTV1-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U359/entry#A0A8V0YTV1-1", "sequence": { "sequence": "MSKTGSKQRLQRHFSGISVVDRLKCTGSEKMSPSIKNLDCFSPMLCHCKVACTNNTISLMFGCKKYRYQDEDTPPQEHSSPHIANEVTGPELVHVSEKNLSQIENVHGFVSHSHISPVKANPPPVLVNTDSLDTPTYVNGTDADYEYEEITLERGNSGLGFSIAGGTDNPHIGDDSSIFITKIIAGGAAAQDGRLRVNDCILRVNEVDVRDVTHSKAVEALKEAGSIVRLYVKRRKPVTEKIVEIKLVKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGKLQIGDKLLAVNSVCLEEVTHEEAVTALKNTSDFVYLKVAKPTSMFMNDSYAPPDITNSYSQPVDNHITPSAYLGQSLPPASPGRYSPIPKGMLGDDEITREPRKVVLHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDRIISVNGVDLKAATHEQAATALKNAGQAVTIVAQYRPEEYSRFEAKIHDLREQMMNSSISSGSGSLRTSQKRSLYVRALFDYDKTKDSGLPSQGLNFKFGDILHVINASDDEWWQARQVTPDGESDEIGVIPSKRRVEKKERARLKTVKFNSKTRGEKGEVPDDMGSKGLKHVTSNASDSESSYRGQEEYVLSYEQVNQQEVNYTRPVIVLGPMKDRINDDLISEFPDKFGSCVPHTTRPKRDYEVDGRDYHFVTSREQMEKDIQEHKFIEAGQYNNHLYGTSVQSVREVAEKGKHCILDVSGNAIKRLQIAQLYPISIFIKPKTVENIMEMNKRLTEEQARKTFERAMKLEQEFTEHFTAIIQGDTLEEIYNQVKQIIEEQSGPYIWVPAKEKL", "length": 832, "header": "tr|A0A8V0YTV1-1|A0A3Q2U359_CHICK Computationally mapped isoform of Disks large homolog 1 OS=Gallus gallus OX=9031 GN=DLG1 PE=1 SV=1 CANONICAL=A0A3Q2U359-1" }, "locus": { "chromosome": "9", "start_pos": 12257545, "end_pos": 12166258, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010041832.1", "url": "https://www.ensembl.org/id/ENSGALT00010041832.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024464.1", "url": "https://www.ensembl.org/id/ENSGALP00010024464.1" } ] } }, { "isoform_ac": "A0A8V0Z0M5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U359/entry#A0A8V0Z0M5-1", "sequence": { "sequence": "MNYIFGNNTLLYSRANRGNTGSSHSSIGPKHKQWAKKGSADELRAEPSRWQQILAFFTRRHGFIDCISVAASSTQANPPPVLVNTDSLDTPTYVNGTDADYEYEEITLERGNSGLGFSIAGGTDNPHIGDDSSIFITKIIAGGAAAQDGRLRVNDCILRVNEVDVRDVTHSKAVEALKEAGSIVRLYVKRRKPVTEKIVEIKLVKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGKLQIGDKLLAVNSVCLEEVTHEEAVTALKNTSDFVYLKVAKPTSMFMNDSYAPPDITNSYSQPVDNHITPSAYLGQSLPPASPGRYSPIPKGMLGDDEITREPRKVVLHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDRIISVNGVDLKAATHEQAATALKNAGQAVTIVAQYRPEEYSRFEAKIHDLREQMMNSSISSGSGSLRTSQKRSLYVRALFDYDKTKDSGLPSQGLNFKFGDILHVINASDDEWWQARQVTPDGESDEIGVIPSKRRVEKKERARLKTVKFNSKTRGEKGEVPDDMGSKGLIILITDEYGCSKGGQEEYVLSYEQVNQQEVNYTRPVIVLGPMKDRINDDLISEFPDKFGSCVPHTTRPKRDYEVDGRDYHFVTSREQMEKDIQEHKFIEAGQYNNHLYGTSVQSVREVAEKGKHCILDVSGNAIKRLQIAQLYPISIFIKPKTVENIMEMNKRLTEEQARKTFERAMKLEQEFTEHFTAIIQGDTLEEIYNQVKQIIEEQSGPYIWVPAKEKL", "length": 786, "header": "tr|A0A8V0Z0M5-1|A0A3Q2U359_CHICK Computationally mapped isoform of Disks large homolog 1 OS=Gallus gallus OX=9031 GN=DLG1 PE=1 SV=1 CANONICAL=A0A3Q2U359-1" }, "locus": { "chromosome": "9", "start_pos": 12238610, "end_pos": 12166258, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010041825.1", "url": "https://www.ensembl.org/id/ENSGALT00010041825.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024458.1", "url": "https://www.ensembl.org/id/ENSGALP00010024458.1" } ] } }, { "isoform_ac": "A0A8V0Z7P0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U359/entry#A0A8V0Z7P0-1", "sequence": { "sequence": "MDCLCIVTTKKYRYQDEDTPPQEHSSPHIANEVTGPELVHVSEKNLSQIENVHGFVSHSHISPVKPTEAVPSSSPIVPVIPVPPVPAETTVIPSTIPQANPPPVLVNTDSLDTPTYVNGTDADYEYEEITLERGNSGLGFSIAGGTDNPHIGDDSSIFITKIIAGGAAAQDGRLRVNDCILRVNEVDVRDVTHSKAVEALKEAGSIVRLYVKRRKPVTEKIVEIKLVKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGKLQIGDKLLAVNSVCLEEVTHEEAVTALKNTSDFVYLKVAKPTSMFMNDSYAPPDITNSYSQPVDNHITPSAYLGQSLPPASPGRYSPIPKGMLGDDEITREPRKVVLHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDRIISVNGVDLKAATHEQAATALKNAGQAVTIVAQYRPEEYSRFEAKIHDLREQMMNSSISSGSGSLRTSQKRSLYVRALFDYDKTKDSGLPSQGLNFKFGDILHVINASDDEWWQARQVTPDGESDEIGVIPSKRRVEKKERARLKTVKFNSKTRGEKGEVPDDMGSKGLKHVTSNASDSESSYRGQEEYVLSYEQVNQQEVNYTRPVIVLGPMKDRINDDLISEFPDKFGSCVPHTTRPKRDYEVDGRDYHFVTSREQMEKDIQEHKFIEAGQYNNHLYGTSVQSVREVAEKGKHCILDVSGNAIKRLQIAQLYPISIFIKPKTVENIMEMNKRLTEEQARKTFERAMKLEQEFTEHFTAIIQGDTLEEIYNQVKQIIEEQSGPYIWVPAKEKL", "length": 811, "header": "tr|A0A8V0Z7P0-1|A0A8V0Z7P0_CHICK Computationally mapped isoform of Discs large MAGUK scaffold protein 1 OS=Gallus gallus OX=9031 GN=DLG1 PE=1 SV=1 CANONICAL=A0A3Q2U359-1" }, "locus": { "chromosome": "9", "start_pos": 12274231, "end_pos": 12166258, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010041840.1", "url": "https://www.ensembl.org/id/ENSGALT00010041840.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024470.1", "url": "https://www.ensembl.org/id/ENSGALP00010024470.1" } ] } }, { "isoform_ac": "A0A8V0Z7R0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U359/entry#A0A8V0Z7R0-1", "sequence": { "sequence": "MPVRKQDTQRALRLLQEYRSKLSQAEDRQLRNSIERVIGIFQSNLFQALIDIQEFYEVTLLDNPKCIDHSQPSEPIQPVNTWDFSSLPSTTVTSETLPSSLSPSVEKYRYQDEDTPPQEHSSPHIANEVTGPELVHVSEKNLSQIENVHGFVSHSHISPVKANPPPVLVNTDSLDTPTYVNGTDADYEYEEITLERGNSGLGFSIAGGTDNPHIGDDSSIFITKIIAGGAAAQDGRLRVNDCILRVNEVDVRDVTHSKAVEALKEAGSIVRLYVKRRKPVTEKIVEIKLVKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGKLQIGDKLLAVNSVCLEEVTHEEAVTALKNTSDFVYLKVAKPTSMFMNDSYAPPDITNSYSQPVDNHITPSAYLGQSLPPASPGRYSPIPKGMLGDDEITREPRKVVLHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDRIISVNGVDLKAATHEQAATALKNAGQAVTIVAQYRPEEYSRFEAKIHDLREQMMNSSISSGSGSLRTSQKRSLYVRALFDYDKTKDSGLPSQGLNFKFGDILHVINASDDEWWQARQVTPDGESDEIGVIPSKRRVEKKERARLKTVKFNSKTRGEKGQSFNDKRKKNLFSRKFPFYKNKDQSEQETSDIDQHVTSNASDSESSYRGQEEYVLSYEQVNQQEVNYTRPVIVLGPMKDRINDDLISEFPDKFGSCVPHTTRPKRDYEVDGRDYHFVTSREQMEKDIQEHKFIEAGQYNNHLYGTSVQSVREVAEKGKHCILDVSGNAIKRLQIAQLYPISIFIKPKTVENIMEMNKRLTEEQARKTFERAMKLEQEFTEHFTAIIQGDTLEEIYNQVKQIIEEQSGPYIWVPAKEKL", "length": 896, "header": "tr|A0A8V0Z7R0-1|A0A3Q2U359_CHICK Computationally mapped isoform of Disks large homolog 1 OS=Gallus gallus OX=9031 GN=DLG1 PE=1 SV=1 CANONICAL=A0A3Q2U359-1" }, "locus": { "chromosome": "9", "start_pos": 12296452, "end_pos": 12166258, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010041870.1", "url": "https://www.ensembl.org/id/ENSGALT00010041870.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024490.1", "url": "https://www.ensembl.org/id/ENSGALP00010024490.1" } ] } }, { "isoform_ac": "E1BT38-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U359/entry#E1BT38-1", "sequence": { "sequence": "MPVRKQDTQRALRLLQEYRSKLSQAEDRQLRNSIERVIGIFQSNLFQALIDIQEFYEVTLLDNPKCIDHSQPSEPIQPVNTWDFSSLPSTTVTSETLPSSLSPSVEKYRYQDEDTPPQEHSSPHIANEVTGPELVHVSEKNLSQIENVHGFVSHSHISPVKPTEAVPSSSPIVPVIPVPPVPAETTVIPSTIPQANPPPVLVNTDSLDTPTYVNGTDADYEYEEITLERGNSGLGFSIAGGTDNPHIGDDSSIFITKIIAGGAAAQDGRLRVNDCILRVNEVDVRDVTHSKAVEALKEAGSIVRLYVKRRKPVTEKIVEIKLVKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGKLQIGDKLLAVNSVCLEEVTHEEAVTALKNTSDFVYLKVAKPTSMFMNDSYAPPDITNSYSQPVDNHITPSAYLGQSLPPASPGRYSPIPKGMLGDDEITREPRKVVLHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDRIISVNGVDLKAATHEQAATALKNAGQAVTIVAQYRPEEYSRFEAKIHDLREQMMNSSISSGSGSLRTSQKRSLYVRALFDYDKTKDSGLPSQGLNFKFGDILHVINASDDEWWQARQVTPDGESDEIGVIPSKRRVEKKERARLKTVKFNSKTRGEKGEVPDDMGSKGLIILITDEYGCSKGGQEEYVLSYEQVNQQEVNYTRPVIVLGPMKDRINDDLISEFPDKFGSCVPHTTRPKRDYEVDGRDYHFVTSREQMEKDIQEHKFIEAGQYNNHLYGTSVQSVREVAEKGKHCILDVSGNAIKRLQIAQLYPISIFIKPKTVENIMEMNKRLTEEQARKTFERAMKLEQEFTEHFTAIIQGDTLEEIYNQVKQIIEEQSGPYIWVPAKEKL", "length": 905, "header": "tr|E1BT38-1|A0A3Q2U359_CHICK Computationally mapped isoform of Disks large homolog 1 OS=Gallus gallus OX=9031 GN=DLG1 PE=1 SV=2 CANONICAL=A0A3Q2U359-1" }, "locus": { "chromosome": "9", "start_pos": 12296452, "end_pos": 12166258, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010041865.1", "url": "https://www.ensembl.org/id/ENSGALT00010041865.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024488.1", "url": "https://www.ensembl.org/id/ENSGALP00010024488.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:424890", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424890", "resource": "KEGG Pathway" }, { "id": "R-GGA-438066", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-438066", "resource": "Reactome", "description": "Unblocking of NMDA receptors, glutamate binding and activation" }, { "id": "R-GGA-5673001", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5673001", "resource": "Reactome", "description": "RAF/MAP kinase cascade" }, { "id": "R-GGA-8849932", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8849932", "resource": "Reactome", "description": "Synaptic adhesion-like molecules" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 24, "go_terms": [ { "name": "neuromuscular junction", "id": "GO:0031594", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031594", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U359", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U359" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U359", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U359" } ], "pmid": "" }, { "name": "apical plasma membrane", "id": "GO:0016324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016324", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U359", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U359" } ], "pmid": "" }, { "name": "neuron projection", "id": "GO:0043005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043005", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U359", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U359" } ], "pmid": "" }, { "name": "anchoring junction", "id": "GO:0070161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070161", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U359", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U359" } ], "pmid": "" }, { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U359", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U359" } ], "pmid": "" }, { "name": "myelin sheath abaxonal region", "id": "GO:0035748", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035748", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U359", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U359" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U359", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U359" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U359", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U359" } ], "pmid": "" }, { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U359", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U359" } ], "pmid": "" }, { "name": "bicellular tight junction", "id": "GO:0005923", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005923", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U359", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U359" } ], "pmid": "" }, { "name": "basolateral plasma membrane", "id": "GO:0016323", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016323", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U359", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U359" } ], "pmid": "" }, { "name": "membrane raft", "id": "GO:0045121", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045121", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U359", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U359" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U359", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U359" } ], "pmid": "" }, { "name": "cytoplasmic side of plasma membrane", "id": "GO:0009898", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009898", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U359", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U359" } ], "pmid": "" }, { "name": "lateral plasma membrane", "id": "GO:0016328", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016328", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U359", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U359" } ], "pmid": "" }, { "name": "basement membrane", "id": "GO:0005604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005604", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U359", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U359" } ], "pmid": "" }, { "name": "node of Ranvier", "id": "GO:0033268", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033268", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U359", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U359" } ], "pmid": "" }, { "name": "cell projection membrane", "id": "GO:0031253", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031253", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U359", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U359" } ], "pmid": "" }, { "name": "immunological synapse", "id": "GO:0001772", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001772", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U359", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U359" } ], "pmid": "" }, { "name": "postsynaptic density membrane", "id": "GO:0098839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098839", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U359", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U359" } ], "pmid": "" }, { "name": "lateral loop", "id": "GO:0043219", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043219", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U359", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U359" } ], "pmid": "" }, { "name": "MPP7-DLG1-LIN7 complex", "id": "GO:0097025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097025", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U359", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U359" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U359", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U359" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 29, "go_terms": [ { "name": "chemical synaptic transmission", "id": "GO:0007268", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007268", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U359", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U359" } ], "pmid": "" }, { "name": "membrane repolarization during ventricular cardiac muscle cell action potential", "id": "GO:0098915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098915", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U359", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U359" } ], "pmid": "" }, { "name": "regulation of protein localization to synapse", "id": "GO:1902473", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902473", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U359", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U359" } ], "pmid": "" }, { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U359", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U359" } ], "pmid": "" }, { "name": "actin filament organization", "id": "GO:0007015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007015", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U359", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U359" } ], "pmid": "" }, { "name": "nervous system development", "id": "GO:0007399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007399", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U359", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U359" } ], "pmid": "" }, { "name": "protein localization to plasma membrane", "id": "GO:0072659", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072659", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U359", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U359" } ], "pmid": "" }, { "name": "positive regulation of potassium ion transport", "id": "GO:0043268", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043268", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U359", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U359" } ], "pmid": "" }, { "name": "cell-cell adhesion", "id": "GO:0098609", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098609", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U359", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U359" } ], "pmid": "" }, { "name": "negative regulation of ERK1 and ERK2 cascade", "id": "GO:0070373", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070373", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U359", "url": 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"https://www.ncbi.nlm.nih.gov/gene/423589", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019748", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019748", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019749", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019749", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035963", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035963", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037837", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037837", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037843", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037843", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040790", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040790", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:423589", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423589", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A1D5PU09", "url": "https://www.orthodb.org/?gene=A0A1D5PU09", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z546", "url": "https://www.orthodb.org/?gene=A0A8V0Z546", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z661", "url": "https://www.orthodb.org/?gene=A0A8V0Z661", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z665", "url": "https://www.orthodb.org/?gene=A0A8V0Z665", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z669", "url": "https://www.orthodb.org/?gene=A0A8V0Z669", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1C0T6", "url": "https://www.orthodb.org/?gene=E1C0T6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16160", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16160", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16160:SF11", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16160:SF11", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00373", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00373", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18124", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18124", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-446353", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-446353", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9013149", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013149", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9013423", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013423", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_004936584", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004936584", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PU09", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PU09", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PU09-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PU09-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z546", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z546", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z546-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z546-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z661", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z661", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z661-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z661-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z665", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z665", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z665-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z665-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z669", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z669", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z669-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z669-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C0T6", "url": "https://www.uniprot.org/uniprotkb/E1C0T6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C0T6-1", "url": "https://www.uniprot.org/uniprotkb/E1C0T6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEGGSASPGLGSMNHDAKEAGAMALDGIRMPDGCYADGTWELSVHVTDLGRDVTLRVTGEIHIGGVMLRLVEKLDVKKDWSDHALWWEKKKTWLLKTHWTLDKYGIQADAKLQFTPQHKLLRLQLPNMKYVKVKVNFSDRVFKAVSDICKTFNIRHPEELSLLRKPRDPSKKKKKKLDDQCDDEAFELEGPLITPGSGTDILYIGPVKGNIYSSPGLYSKTMTPTYDAHDGSPLSPTSAWFGDSALSEGNPGILAVSQPVTSPESLAKMYKPQALLDKAKINQGWLDSSRSLMEQEVKENEALLLRFKYYSFFDLNPKYDAIRINQLYEQSKWAILLEEIECTEEEMMMFAALQYHINKLSIMSSENHLNNSDKDVDEVDAALSDLEITLEGGKTSTILGDITSIPELADYIKVFKPKKLTLKGYKPYWCTFKDTSISCYKSKEEANGTPAHQMNLRGCEVTPDVNISGQKFNIKLLIPVAEGMNEIWLRCDNERQYASWMAACRLASKGKTMADSSYSMEVQNILSFLKMQHLNPDPQLIPEQITTDINPECLVSPRYLKKYKNKQPGYVRDLLTARILEAHQNVAQMSLIEAKMRFIQAWQSLPEFGITHFIARFQGGKKEELIGIAYNRLIRMDASTGDAIKTWRFSNMKQWNVNWEIKMVTVEFADDVRVSFICTEVDCKVVHEFIGGYIFLSTRAKDQNESLDEEMFYKLTSGWV", "length": 720, "header": "tr|A0A1D5PU09-1|A0A1D5PU09_CHICK Isoform 1 of FERM domain containing kindlin 2 OS=Gallus gallus OX=9031 GN=FERMT2 PE=1 SV=1 CANONICAL=A0A1D5PU09-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PU09-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PU09/entry#A0A1D5PU09-1", "sequence": { "sequence": "MEGGSASPGLGSMNHDAKEAGAMALDGIRMPDGCYADGTWELSVHVTDLGRDVTLRVTGEIHIGGVMLRLVEKLDVKKDWSDHALWWEKKKTWLLKTHWTLDKYGIQADAKLQFTPQHKLLRLQLPNMKYVKVKVNFSDRVFKAVSDICKTFNIRHPEELSLLRKPRDPSKKKKKKLDDQCDDEAFELEGPLITPGSGTDILYIGPVKGNIYSSPGLYSKTMTPTYDAHDGSPLSPTSAWFGDSALSEGNPGILAVSQPVTSPESLAKMYKPQALLDKAKINQGWLDSSRSLMEQEVKENEALLLRFKYYSFFDLNPKYDAIRINQLYEQSKWAILLEEIECTEEEMMMFAALQYHINKLSIMSSENHLNNSDKDVDEVDAALSDLEITLEGGKTSTILGDITSIPELADYIKVFKPKKLTLKGYKPYWCTFKDTSISCYKSKEEANGTPAHQMNLRGCEVTPDVNISGQKFNIKLLIPVAEGMNEIWLRCDNERQYASWMAACRLASKGKTMADSSYSMEVQNILSFLKMQHLNPDPQLIPEQITTDINPECLVSPRYLKKYKNKQPGYVRDLLTARILEAHQNVAQMSLIEAKMRFIQAWQSLPEFGITHFIARFQGGKKEELIGIAYNRLIRMDASTGDAIKTWRFSNMKQWNVNWEIKMVTVEFADDVRVSFICTEVDCKVVHEFIGGYIFLSTRAKDQNESLDEEMFYKLTSGWV", "length": 720, "header": "tr|A0A1D5PU09-1|A0A1D5PU09_CHICK Isoform 1 of FERM domain containing kindlin 2 OS=Gallus gallus OX=9031 GN=FERMT2 PE=1 SV=1 CANONICAL=A0A1D5PU09-1" }, "locus": { "chromosome": "5", "start_pos": 58063116, "end_pos": 58027149, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043814.1", "url": "https://www.ensembl.org/id/ENSGALT00010043814.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026060.1", "url": "https://www.ensembl.org/id/ENSGALP00010026060.1" } ] } }, { "isoform_ac": "A0A8V0Z546-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PU09/entry#A0A8V0Z546-1", "sequence": { "sequence": "MYVKKDWSDHALWWEKKKTWLLKTHWTLDKYGIQADAKLQFTPQHKLLRLQLPNMKYVKVKVNFSDRVFKAVSDICKTFNIRHPEELSLLRKPRDPSKKKKKKLDDQCDDEAFELEGPLITPGSGNIYSSPGLYSKTMTPTYDAHDGSPLSPTSAWFGDSALSEGNPGILAVSQPVTSPESLAKMYKPQALLDKAKINQGWLDSSRSLMEQEVKENEALLLRFKYYSFFDLNPKYDAIRINQLYEQSKWAILLEEIECTEEEMMMFAALQYHINKLSIMSSENHLNNSDKDVDEVDAALSDLEITLEGGKTSTILGDITSIPELADYIKVFKPKKLTLKGYKPYWCTFKDTSISCYKSKEEANGTPAHQMNLRGCEVTPDVNISGQKFNIKLLIPVAEGMNEIWLRCDNRQYASWMAACRLASKGKTMADSSYSMEVQNILSFLKMQHLNPDPQLIPEQITTDINPECLVSPRYLKKYKNKQPGYVRDLLTARILEAHQNVAQMSLIEAKMRFIQAWQSLPEFGITHFIARFQGGKKEELIGIAYNRLIRMDASTGDAIKTWRFSNMKQWNVNWEIKMVTVEFADDVRVSFICTEVDCKVVHEFIGGYIFLSTRAKDQNESLDEEMFYKLTSGWV", "length": 635, "header": "tr|A0A8V0Z546-1|A0A8V0Z546_CHICK Computationally mapped isoform of FERM domain containing kindlin 2 OS=Gallus gallus OX=9031 GN=FERMT2 PE=1 SV=1 CANONICAL=A0A1D5PU09-1" }, "locus": { "chromosome": "5", "start_pos": 58058155, "end_pos": 58027149, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043786.1", "url": "https://www.ensembl.org/id/ENSGALT00010043786.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026041.1", "url": "https://www.ensembl.org/id/ENSGALP00010026041.1" } ] } }, { "isoform_ac": "A0A8V0Z661-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PU09/entry#A0A8V0Z661-1", "sequence": { "sequence": "MPGGRRARIIADVKKDWSDHALWWEKKKTWLLKTHWTLDKYGIQADAKLQFTPQHKLLRLQLPNMKYVKVKVNFSDRVFKAVSDICKTFNIRHPEELSLLRKPRDPSKKKKKKLDDQCDDEAFELEGPLITPGSGNIYSSPGLYSKTMTPTYDAHDGSPLSPTSAWFGDSALSEGNPGILAVSQPVTSPESLAKMYKPQALLDKAKINQGWLDSSRSLMEQEVKENEALLLRFKYYSFFDLNPKYDAIRINQLYEQSKWAILLEEIECTEEEMMMFAALQYHINKLSIMSSENHLNNSDKDVDEVDAALSDLEITLEGGKTSTILGDITSIPELADYIKVFKPKKLTLKGYKPYWCTFKDTSISCYKSKEEANGTPAHQMNLRGCEVTPDVNISGQKFNIKLLIPVAEGMNEIWLRCDNRQYASWMAACRLASKGKTMADSSYSMEVQNILSFLKMQHLNPDPQLIPEQITTDINPECLVSPRYLKKYKNKQPGYVRDLLTARILEAHQNVAQMSLIEAKMRFIQAWQSLPEFGITHFIARFQGGKKEELIGIAYNRLIRMDASTGDAIKTWRFSNMKQWNVNWEIKMVTVEFADDVRVSFICTEVDCKVVHEFIGGYIFLSTRAKDQNESLDEEMFYKLTSGWV", "length": 645, "header": "tr|A0A8V0Z661-1|A0A8V0Z661_CHICK Computationally mapped isoform of FERM domain containing kindlin 2 OS=Gallus gallus OX=9031 GN=FERMT2 PE=1 SV=1 CANONICAL=A0A1D5PU09-1" }, "locus": { "chromosome": "5", "start_pos": 58058451, "end_pos": 58027149, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043792.1", "url": "https://www.ensembl.org/id/ENSGALT00010043792.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026045.1", "url": "https://www.ensembl.org/id/ENSGALP00010026045.1" } ] } }, { "isoform_ac": "A0A8V0Z665-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PU09/entry#A0A8V0Z665-1", "sequence": { "sequence": "MALDGIRMPDGCYADGTWELSVHVTDLGRDVTLRVTGEIHIGGVMLRLVEKLDVKKDWSDHALWWEKKKTWLLKTHWTLDKYGIQADAKLQFTPQHKLLRLQLPNMKYVKVKVNFSDRVFKAVSDICKTFNIRHPEELSLLRKPRDPSKKKKKKLDDQCDDEAFELEGPLITPGSGNIYSSPGLYSKTMTPTYDAHDGSPLSPTSAWFGDSALSEGNPGILAVSQPVTSPESLAKMYKPQALLDKAKINQGWLDSSRSLMEQEVKENEALLLRFKYYSFFDLNPKYDAIRINQLYEQSKWAILLEEIECTEEEMMMFAALQYHINKLSIMSSENHLNNSDKDVDEVDAALSDLEITLEGGKTSTILGDITSIPELADYIKVFKPKKLTLKGYKPYWCTFKDTSISCYKSKEEANGTPAHQMNLRGCEVTPDVNISGQKFNIKLLIPVAEGMNEIWLRCDNERQYASWMAACRLASKGKTMADSSYSMEVQNILSFLKMQHLNPDPQLIPEQITTDINPECLVSPRYLKKYKNKQLTARILEAHQNVAQMSLIEAKMRFIQAWQSLPEFGITHFIARFQGGKKEELIGIAYNRLIRMDASTGDAIKTWRFSNMKQWNVNWEIKMRWIAKWCMSSLVVTSSCRREQRTRTRAWMRRCSTN", "length": 658, "header": "tr|A0A8V0Z665-1|A0A8V0Z665_CHICK Computationally mapped isoform of FERM domain containing kindlin 2 OS=Gallus gallus OX=9031 GN=FERMT2 PE=1 SV=1 CANONICAL=A0A1D5PU09-1" }, "locus": { "chromosome": "5", "start_pos": 58062476, "end_pos": 58027166, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043797.1", "url": "https://www.ensembl.org/id/ENSGALT00010043797.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026050.1", "url": "https://www.ensembl.org/id/ENSGALP00010026050.1" } ] } }, { "isoform_ac": "A0A8V0Z669-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PU09/entry#A0A8V0Z669-1", "sequence": { "sequence": "MLEQPPLRSVLFHKRPRGSAEAGAMALDGIRMPDGCYADGTWELSVHVTDLGRDVTLRVTGEIHIGGVMLRLVEKLDVKKDWSDHALWWEKKKTWLLKTHWTLDKYGIQADAKLQFTPQHKLLRLQLPNMKYVKVKVNFSDRVFKAVSDICKTFNIRHPEELSLLRKPRDPSKKKKKKLDDQCDDEAFELEGPLITPGSGNIYSSPGLYSKTMTPTYDAHDGSPLSPTSAWFGDSALSEGNPGILAVSQPVTSPESLAKMYKPQALLDKAKINQGWLDSSRSLMEQEVKENEALLLRFKYYSFFDLNPKYDAIRINQLYEQSKWAILLEEIECTEEEMMMFAALQYHINKLSIMSSENHLNNSDKDVDEVDAALSDLEITLEGGKTSTILGDITSIPELADYIKVFKPKKLTLKGYKPYWCTFKDTSISCYKSKEEANGTPAHQMNLRGCEVTPDVNISGQKFNIKLLIPVAEGMNEIWLRCDNERQYASWMAACRLASKGKTMADSSYSMEVQNILSFLKMQHLNPDPQLIPEQITTDINPECLVSPRYLKKYKNKQLTARILEAHQNVAQMSLIEAKMRFIQAWQSLPEFGITHFIARFQGGKKEELIGIAYNRLIRMDASTGDAIKTWRFSNMKQWNVNWEIKMVTVEFADDVRVSFICTEVDCKVVHEFIGGYIFLSTRAKDQNESLDEEMFYKLTSGWV", "length": 704, "header": "tr|A0A8V0Z669-1|A0A8V0Z669_CHICK Computationally mapped isoform of FERM domain containing kindlin 2 OS=Gallus gallus OX=9031 GN=FERMT2 PE=1 SV=1 CANONICAL=A0A1D5PU09-1" }, "locus": { "chromosome": "5", "start_pos": 58062810, "end_pos": 58027149, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043805.1", "url": "https://www.ensembl.org/id/ENSGALT00010043805.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026055.1", "url": "https://www.ensembl.org/id/ENSGALP00010026055.1" } ] } }, { "isoform_ac": "E1C0T6-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PU09/entry#E1C0T6-1", "sequence": { "sequence": "MEGGSASPGLGSMNHDAKEAGAMALDGIRMPDGCYADGTWELSVHVTDLGRDVTLRVTGEIHIGGVMLRLVEKLDVKKDWSDHALWWEKKKTWLLKTHWTLDKYGIQADAKLQFTPQHKLLRLQLPNMKYVKVKVNFSDRVFKAVSDICKTFNIRHPEELSLLRKPRDPSKKKKKKLDDQCDDEAFELEGPLITPGSGNIYSSPGLYSKTMTPTYDAHDGSPLSPTSAWFGDSALSEGNPGILAVSQPVTSPESLAKMYKPQALLDKAKINQGWLDSSRSLMEQEVKENEALLLRFKYYSFFDLNPKYDAIRINQLYEQSKWAILLEEIECTEEEMMMFAALQYHINKLSIMSSENHLNNSDKDVDEVDAALSDLEITLEGGKTSTILGDITSIPELADYIKVFKPKKLTLKGYKPYWCTFKDTSISCYKSKEEANGTPAHQMNLRGCEVTPDVNISGQKFNIKLLIPVAEGMNEIWLRCDNERQYASWMAACRLASKGKTMADSSYSMEVQNILSFLKMQHLNPDPQLIPEQITTDINPECLVSPRYLKKYKNKQPGYVRDLLTARILEAHQNVAQMSLIEAKMRFIQAWQSLPEFGITHFIARFQGGKKEELIGIAYNRLIRMDASTGDAIKTWRFSNMKQWNVNWEIKMVTVEFADDVRVSFICTEVDCKVVHEFIGGYIFLSTRAKDQNESLDEEMFYKLTSGWV", "length": 709, "header": "tr|E1C0T6-1|A0A1D5PU09_CHICK Computationally mapped isoform of FERM domain containing kindlin 2 OS=Gallus gallus OX=9031 GN=FERMT2 PE=1 SV=3 CANONICAL=A0A1D5PU09-1" }, "locus": { "chromosome": "5", "start_pos": 58063116, "end_pos": 58027149, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043824.1", "url": "https://www.ensembl.org/id/ENSGALT00010043824.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026066.1", "url": "https://www.ensembl.org/id/ENSGALP00010026066.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:423589", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423589", "resource": "KEGG Pathway" }, { "id": "R-GGA-446353", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-446353", "resource": "Reactome", "description": "Cell-extracellular matrix interactions" }, { "id": "R-GGA-9013149", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013149", "resource": "Reactome", "description": "RAC1 GTPase cycle" }, { "id": "R-GGA-9013423", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013423", "resource": "Reactome", "description": "RAC3 GTPase cycle" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 7, "go_terms": [ { "name": "integrin binding", "id": "GO:0005178", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005178", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PU09", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PU09" } ], "pmid": "" }, { "name": "phosphatidylinositol-3,4,5-trisphosphate binding", "id": "GO:0005547", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005547", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PU09", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PU09" } ], "pmid": "" }, { "name": "actin filament binding", "id": "GO:0051015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051015", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PU09", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PU09" } ], "pmid": "" }, { "name": "SMAD binding", "id": "GO:0046332", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046332", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PU09", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PU09" } ], "pmid": "" }, { "name": "protein serine/threonine kinase activator activity", "id": "GO:0043539", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043539", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PU09", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PU09" } ], "pmid": "" }, { "name": "type I transforming growth factor beta receptor binding", "id": "GO:0034713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034713", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PU09", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PU09" } ], "pmid": "" }, { "name": "protein serine/threonine kinase binding", "id": "GO:0120283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120283", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PU09", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PU09" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 8, "go_terms": [ 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"id": "R-GGA-9696264", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9696264", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9696270", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9696270", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-983695", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9842663", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9842663", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9927354", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9927354", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015133112", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015133112", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PUK7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUK7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PUK7-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUK7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2UF03", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UF03", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2UF03-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UF03-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q3ACS4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3ACS4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q3ACS4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3ACS4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y6S9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6S9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y6S9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6S9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C8M4", "url": "https://www.uniprot.org/uniprotkb/E1C8M4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C8M4-1", "url": "https://www.uniprot.org/uniprotkb/E1C8M4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSAEGYQYRALYDYKKEREEDIDLHLGDILTVNKGTLLALGFNEGEEAKPEEIGWLNGFNETTGERGDFPGTYVEYIGRKKISPPTPKPRPPRPLPVAPSPSKADAESEQQAFSLPDLTEQFSPPDVAPPILIKIIETIEKKGLECSTLYVTQSSSSSAELRQILECDASSLDLETFDVHTLSDALKRYLLDLPNPIIPATVYSDIISVAQDVQSSEEYAQLLKKLIRSPNIPHQYWLTLQYLLKHFLRLCQASSKNLLNARSLAEIFSPLLFKFQIASSDNAEHHIRILEILITSEWNERQPVPALPPKPPKPNTVTNNGMNNNMSLQDAEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHRDGKYGFSDPLTFNSVVELINHYRNESLAQYNPKLDVKLLYPVSKYQQDQVVKEDSIEAVGKKLHEYNTQFQEKSREYDRLYEDYTRTSQEIQMKRTAIEAFNETIKIFEEQCQTQERYSKEYIEKFKREGNEKEIQRIMHNYEKLKSRISEIVDSRRRLEEDLKKQAAEYREIDKRMNSIKPDLIQLRKTRDQYLMWLTQKGVRQKKLNEWLGNENTEDQYSMVDDDEDLPHHDERTWNVGNINRSQAENLLRGKRDGTFLVRESSKQGCYACSVVVDGEVKHCVINKTPTGYGFAEPYNLYNSLKELVLHYQHTSLVQHNDSLNVTLAYPVYAQQRR", "length": 724, "header": "tr|A0A3Q3ACS4-1|A0A3Q3ACS4_CHICK Isoform 1 of Phosphatidylinositol 3-kinase regulatory subunit alpha OS=Gallus gallus OX=9031 GN=PIK3R1 PE=1 SV=1 CANONICAL=A0A3Q3ACS4-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PUK7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3ACS4/entry#A0A1D5PUK7-1", "sequence": { "sequence": "MYNTVWNMEELDIEYPKTDINCGTDLMFYIEMDPPALPPKPPKPNTVTNNGMNNNMSLQDAEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHRDGKYGFSDPLTFNSVVELINHYRNESLAQYNPKLDVKLLYPVSKYQQDQVVKEDSIEAVGKKLHEYNTQFQEKSREYDRLYEDYTRTSQEIQMKRTAIEAFNETIKIFEEQCQTQERYSKEYIEKFKREGNEKEIQRIMHNYEKLKSRISEIVDSRRRLEEDLKKQAAEYREIDKRMNSIKPDLIQLRKTRDQYLMWLTQKGVRQKKLNEWLGNENTEDQYSMVDDDEDLPHHDERTWNVGNINRSQAENLLRGKRDGTFLVRESSKQGCYACSVVVDGEVKHCVINKTPTGYGFAEPYNLYNSLKELVLHYQHTSLVQHNDSLNVTLAYPVYAQQRR", "length": 454, "header": "tr|A0A1D5PUK7-1|A0A1D5PUK7_CHICK Computationally mapped isoform of Phosphoinositide-3-kinase regulatory subunit 1 OS=Gallus gallus OX=9031 GN=PIK3R1 PE=1 SV=1 CANONICAL=A0A3Q3ACS4-1" }, "locus": { "chromosome": "Z", "start_pos": 22195987, "end_pos": 22188655, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028516.1", "url": "https://www.ensembl.org/id/ENSGALT00010028516.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016364.1", "url": "https://www.ensembl.org/id/ENSGALP00010016364.1" } ] } }, { "isoform_ac": "A0A3Q2UF03-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3ACS4/entry#A0A3Q2UF03-1", "sequence": { "sequence": "MIALSEKLILDCSKGIYKVAQILKSGFGSPNVCVLLQHASKQKILLKSAFSLPDLTEQFSPPDVAPPILIKIIETIEKKGLECSTLYVTQSSSSSAELRQILECDASSLDLETFDVHTLSDALKRYLLDLPNPIIPATVYSDIISVAQDVQSSEEYAQLLKKLIRSPNIPHQYWLTLQYLLKHFLRLCQASSKNLLNARSLAEIFSPLLFKFQIASSDNAEHHIRILEILITSEWNERQPVPALPPKPPKPNTVTNNGMNNNMSLQDAEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHRDGKYGFSDPLTFNSVVELINHYRNESLAQYNPKLDVKLLYPVSKYQQDQVVKEDSIEAVGKKLHEYNTQFQEKSREYDRLYEDYTRTSQEIQMKRTAIEAFNETIKIFEEQCQTQERYSKEYIEKFKREGNEKEIQRIMHNYEKLKSRISEIVDSRRRLEEDLKKQAAEYREIDKRMNSIKPDLIQLRKTRDQYLMWLTQKGVRQKKLNEWLGNENTEDQYSMVDDDEDLPHHDERTWNVGNINRSQAENLLRGKRDGTFLVRESSKQGCYACSVVVDGEVKHCVINKTPTGYGFAEPYNLYNSLKELVLHYQHTSLVQHNDSLNVTLAYPVYAQQRR", "length": 661, "header": "tr|A0A3Q2UF03-1|A0A3Q2UF03_CHICK Computationally mapped isoform of Phosphoinositide-3-kinase regulatory subunit 1 OS=Gallus gallus OX=9031 GN=PIK3R1 PE=1 SV=1 CANONICAL=A0A3Q3ACS4-1" }, "locus": { "chromosome": "Z", "start_pos": 22195987, "end_pos": 22170661, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028520.1", "url": "https://www.ensembl.org/id/ENSGALT00010028520.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016368.1", "url": "https://www.ensembl.org/id/ENSGALP00010016368.1" } ] } }, { "isoform_ac": "A0A3Q3ACS4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3ACS4/entry#A0A3Q3ACS4-1", "sequence": { "sequence": "MSAEGYQYRALYDYKKEREEDIDLHLGDILTVNKGTLLALGFNEGEEAKPEEIGWLNGFNETTGERGDFPGTYVEYIGRKKISPPTPKPRPPRPLPVAPSPSKADAESEQQAFSLPDLTEQFSPPDVAPPILIKIIETIEKKGLECSTLYVTQSSSSSAELRQILECDASSLDLETFDVHTLSDALKRYLLDLPNPIIPATVYSDIISVAQDVQSSEEYAQLLKKLIRSPNIPHQYWLTLQYLLKHFLRLCQASSKNLLNARSLAEIFSPLLFKFQIASSDNAEHHIRILEILITSEWNERQPVPALPPKPPKPNTVTNNGMNNNMSLQDAEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHRDGKYGFSDPLTFNSVVELINHYRNESLAQYNPKLDVKLLYPVSKYQQDQVVKEDSIEAVGKKLHEYNTQFQEKSREYDRLYEDYTRTSQEIQMKRTAIEAFNETIKIFEEQCQTQERYSKEYIEKFKREGNEKEIQRIMHNYEKLKSRISEIVDSRRRLEEDLKKQAAEYREIDKRMNSIKPDLIQLRKTRDQYLMWLTQKGVRQKKLNEWLGNENTEDQYSMVDDDEDLPHHDERTWNVGNINRSQAENLLRGKRDGTFLVRESSKQGCYACSVVVDGEVKHCVINKTPTGYGFAEPYNLYNSLKELVLHYQHTSLVQHNDSLNVTLAYPVYAQQRR", "length": 724, "header": "tr|A0A3Q3ACS4-1|A0A3Q3ACS4_CHICK Isoform 1 of Phosphatidylinositol 3-kinase regulatory subunit alpha OS=Gallus gallus OX=9031 GN=PIK3R1 PE=1 SV=1 CANONICAL=A0A3Q3ACS4-1" }, "locus": { "chromosome": "Z", "start_pos": 22195987, "end_pos": 22145375, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028522.1", "url": "https://www.ensembl.org/id/ENSGALT00010028522.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016370.1", "url": "https://www.ensembl.org/id/ENSGALP00010016370.1" } ] } }, { "isoform_ac": "A0A8V0Y6S9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3ACS4/entry#A0A8V0Y6S9-1", "sequence": { "sequence": "MVLISNRQLAGFQLIGQVFCYVQSSEEYAQLLKKLIRSPNIPHQYWLTLQYLLKHFLRLCQASSKNLLNARSLAEIFSPLLFKFQIASSDNAEHHIRILEILITSEWNERQPVPALPPKPPKPNTVTNNGMNNNMSLQDAEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHRDGKYGFSDPLTFNSVVELINHYRNESLAQYNPKLDVKLLYPVSKYQQDQVVKEDSIEAVGKKLHEYNTQFQEKSREYDRLYEDYTRTSQEIQMKRTAIEAFNETIKIFEEQCQTQERYSKEYIEKFKREGNEKEIQRIMHNYEKLKSRISEIVDSRRRLEEDLKKQAAEYREIDKRMNSIKPDLIQLRKTRDQYLMWLTQKGVRQKKLNEWLGNENTEDQYSMVDDDEDLPHHDERTWNVGNINRSQAENLLRGKRDGTFLVRESSKQGCYACSVVVDGEVKHCVINKTPTGYGFAEPYNLYNSLKELVLHYQHTSLVQHNDSLNVTLAYPVYAQQRR", "length": 533, "header": "tr|A0A8V0Y6S9-1|A0A3Q3ACS4_CHICK Computationally mapped isoform of Phosphatidylinositol 3-kinase regulatory subunit alpha OS=Gallus gallus OX=9031 GN=PIK3R1 PE=1 SV=1 CANONICAL=A0A3Q3ACS4-1" }, "locus": { "chromosome": "Z", "start_pos": 22195987, "end_pos": 22179792, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028519.1", "url": "https://www.ensembl.org/id/ENSGALT00010028519.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016367.1", "url": "https://www.ensembl.org/id/ENSGALP00010016367.1" } ] } }, { "isoform_ac": "E1C8M4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3ACS4/entry#E1C8M4-1", "sequence": { "sequence": "MHNLQTLPPKPPKPNTVTNNGMNNNMSLQDAEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHRDGKYGFSDPLTFNSVVELINHYRNESLAQYNPKLDVKLLYPVSKYQQDQVVKEDSIEAVGKKLHEYNTQFQEKSREYDRLYEDYTRTSQEIQMKRTAIEAFNETIKIFEEQCQTQERYSKEYIEKFKREGNEKEIQRIMHNYEKLKSRISEIVDSRRRLEEDLKKQAAEYREIDKRMNSIKPDLIQLRKTRDQYLMWLTQKGVRQKKLNEWLGNENTEDQYSMVDDDEDLPHHDERTWNVGNINRSQAENLLRGKRDGTFLVRESSKQGCYACSVVVDGEVKHCVINKTPTGYGFAEPYNLYNSLKELVLHYQHTSLVQHNDSLNVTLAYPVYAQQRR", "length": 424, "header": "tr|E1C8M4-1|A0A3Q3ACS4_CHICK Computationally mapped isoform of Phosphatidylinositol 3-kinase regulatory subunit alpha OS=Gallus gallus OX=9031 GN=PIK3R1 PE=1 SV=2 CANONICAL=A0A3Q3ACS4-1" }, "locus": { "chromosome": "Z", "start_pos": 22195987, "end_pos": 22186580, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028517.1", "url": "https://www.ensembl.org/id/ENSGALT00010028517.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016365.1", "url": "https://www.ensembl.org/id/ENSGALP00010016365.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:427171", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427171", "resource": "KEGG Pathway" }, { "id": "R-GGA-109704", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-109704", "resource": "Reactome", "description": "PI3K Cascade" }, { "id": "R-GGA-112399", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-112399", "resource": "Reactome", "description": "IRS-mediated signalling" }, { "id": "R-GGA-114604", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-114604", "resource": "Reactome", "description": "GPVI-mediated activation cascade" }, { "id": "R-GGA-1250342", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1250342", "resource": "Reactome", "description": "PI3K events in ERBB4 signaling" }, { "id": "R-GGA-1257604", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1257604", "resource": "Reactome", "description": "PIP3 activates AKT signaling" }, { "id": "R-GGA-1266695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1266695", "resource": "Reactome", "description": "Interleukin-7 signaling" }, { "id": "R-GGA-1433557", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1433557", "resource": "Reactome", "description": "Signaling by SCF-KIT" }, { "id": "R-GGA-1660499", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1660499", "resource": "Reactome", "description": "Synthesis of PIPs at the plasma membrane" }, { "id": "R-GGA-180292", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-180292", "resource": "Reactome", "description": "GAB1 signalosome" }, { "id": "R-GGA-186763", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-186763", "resource": "Reactome", "description": "Downstream signal transduction" }, { "id": "R-GGA-1963642", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1963642", "resource": "Reactome", "description": "PI3K events in ERBB2 signaling" }, { "id": "R-GGA-198203", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-198203", "resource": "Reactome", "description": "PI3K/AKT activation" }, { "id": "R-GGA-201556", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-201556", "resource": "Reactome", "description": "Signaling by ALK" }, { "id": "R-GGA-202424", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-202424", "resource": "Reactome", "description": "Downstream TCR signaling" }, { "id": "R-GGA-2029485", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2029485", "resource": "Reactome", "description": "Role of phospholipids in phagocytosis" }, { "id": "R-GGA-210993", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-210993", "resource": "Reactome", "description": "Tie2 Signaling" }, { "id": "R-GGA-2730905", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2730905", "resource": "Reactome", "description": "Role of LAT2/NTAL/LAB on calcium mobilization" }, { "id": "R-GGA-389357", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-389357", "resource": "Reactome", "description": "CD28 dependent PI3K/Akt signaling" }, { "id": "R-GGA-416476", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-416476", "resource": "Reactome", "description": "G alpha (q) signalling events" }, { "id": "R-GGA-430116", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-430116", "resource": "Reactome", "description": "GP1b-IX-V activation signalling" }, { "id": "R-GGA-4420097", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4420097", "resource": "Reactome", "description": "VEGFA-VEGFR2 Pathway" }, { "id": "R-GGA-512988", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-512988", "resource": "Reactome", "description": "Interleukin-3, Interleukin-5 and GM-CSF signaling" }, { "id": "R-GGA-5654689", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5654689", "resource": "Reactome", "description": "PI-3K cascade:FGFR1" }, { "id": "R-GGA-5654695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5654695", "resource": "Reactome", "description": "PI-3K cascade:FGFR2" }, { "id": "R-GGA-5654710", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5654710", "resource": "Reactome", "description": "PI-3K cascade:FGFR3" }, { "id": "R-GGA-5654720", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5654720", "resource": "Reactome", "description": "PI-3K cascade:FGFR4" }, { "id": "R-GGA-5673001", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5673001", "resource": "Reactome", "description": "RAF/MAP kinase cascade" }, { "id": "R-GGA-6811558", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6811558", "resource": "Reactome", "description": "PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling" }, { "id": "R-GGA-8851907", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8851907", "resource": "Reactome", "description": "MET activates PI3K/AKT signaling" }, { "id": "R-GGA-8853659", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8853659", "resource": "Reactome", "description": "RET signaling" }, { "id": "R-GGA-8980692", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8980692", "resource": "Reactome", "description": "RHOA GTPase cycle" }, { "id": "R-GGA-9009391", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9009391", "resource": "Reactome", "description": "Extra-nuclear estrogen signaling" }, { "id": "R-GGA-9013026", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013026", "resource": "Reactome", "description": "RHOB GTPase cycle" }, { "id": "R-GGA-9013106", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013106", "resource": "Reactome", "description": "RHOC GTPase cycle" }, { "id": "R-GGA-9013148", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013148", "resource": "Reactome", "description": "CDC42 GTPase cycle" }, { "id": "R-GGA-9013149", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013149", "resource": "Reactome", "description": "RAC1 GTPase cycle" }, { "id": "R-GGA-9013404", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013404", "resource": "Reactome", "description": "RAC2 GTPase cycle" }, { "id": "R-GGA-9013408", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013408", "resource": "Reactome", "description": "RHOG GTPase cycle" }, { "id": "R-GGA-9013409", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013409", "resource": "Reactome", "description": "RHOJ GTPase cycle" }, { "id": "R-GGA-9013420", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013420", "resource": "Reactome", "description": "RHOU GTPase cycle" }, { "id": "R-GGA-9013423", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013423", "resource": "Reactome", "description": "RAC3 GTPase cycle" }, { "id": "R-GGA-9013424", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013424", "resource": "Reactome", "description": "RHOV GTPase cycle" }, { "id": "R-GGA-9027276", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9027276", "resource": "Reactome", "description": "Erythropoietin activates Phosphoinositide-3-kinase (PI3K)" }, { "id": "R-GGA-9035034", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9035034", "resource": "Reactome", "description": "RHOF GTPase cycle" }, { "id": "R-GGA-912526", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-912526", "resource": "Reactome", "description": "Interleukin receptor SHC signaling" }, { "id": "R-GGA-912631", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-912631", "resource": "Reactome", "description": "Regulation of signaling by CBL" }, { "id": "R-GGA-9607240", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9607240", "resource": "Reactome", "description": "FLT3 Signaling" }, { "id": "R-GGA-9696264", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9696264", "resource": "Reactome", "description": "RND3 GTPase cycle" }, { "id": "R-GGA-9696270", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9696270", "resource": "Reactome", "description": "RND2 GTPase cycle" }, { "id": "R-GGA-983695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983695", "resource": "Reactome", "description": "Antigen activates B Cell Receptor (BCR) leading to generation of second messengers" }, { "id": "R-GGA-9842663", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9842663", "resource": "Reactome", "description": "Signaling by LTK" }, { "id": "R-GGA-9927354", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9927354", "resource": "Reactome", "description": "Co-stimulation by ICOS" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2N9Q4-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit alpha", "gene_name": "Pik3r1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSAEGYQYRALYDYKKEREEDIDLHLGDILTVNKGSLVALGFSDGQEARPEDIGWLNGYNETTGERGDFPGTYVEYIGRKRISPPTPKPRPPRPLPVAPGSSKTEADTEQPALTLPDLAEQFAPPDVAPPLLIKLVDAIEKKGLECSTLYRTQSSSNPAELRQLLDCDAASVDLEMIDVQVLADAFKRYLLDLPNPVIPGAVYNEMSLAQEVQSPEDYIQLLKKLIRSPNIPHQYWLTLQYLLKHFFKLSQASSKNLLNSRVLSEIFSPVLFRFPAASSDNTEHLIKVIEILISTEWNERQPAPALPPKPPKTTTVANNGMNNNMSLQDAEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHRDGKYGFSDPLTFNSVVELINHYRNESLAQYNPKLDVKLLYPVSKYQQDQVVKEDNIEAVGKKLHEYNTQFQEKSREYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQCQTQERYSKEYIEKFKREGNEKEIQRIMHNYDKLKSRISEIIDSRRRLEEDLKKQAAEYREIDKRMNSIKPDLIQLRKTRDQYLMWLTQKGVRQKKLNEWLGNENTEDQYSLVEDEEDLPHHDEKTWNVGSSNRNKAENLLRGKRDGTFLVRESSKQGCYACSVVVDGEVKHCVINKTATGYGFAEPYNLYSSLKELVLHYQHTSLVQHNDSLNVTLAYPVYAQQRR", "length": 723 }, "evidence": [ { "id": "A0A3Q3ACS4", "url": "https://omabrowser.org/oma/group/A0A3Q3ACS4/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "B0S6V7-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit alpha", "gene_name": "pik3r1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSAEGYQYRALYDYKKEREEDIDLHVGDILTVNKGALLALGYMEGMEERPDEVGWLPGFNETTQEKGDFPGTYVEFIGKKKISPPTPKPRPPRPLPVAPGPTRQDSDSEQSLSTLLDLTEQFAPPEVAPSMLLKLLEAIEKKGLDNPTLYRNFTAGGGLDVRQCFDSDPASVDLEQMDLQMLCDGLRRYLQDLPQPVIPPVIYNEMIRIAQEVQGTDECAQHLRLVASSTALPPQYWLTLQSLLRHFSHVCQSSAVNLLSARALAEIFSPALFRHQPTSCEPSPEAHIRIIEVLVTSEWSDSQAAPALPPKPPKPTSVANNGMNNNMALQDAEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHRDGKYGFSDPLTFNSVVELINHYRTESLAQYNPKLDVKLLYPVSKHQQDQVVKEDNIEAVGKKLHEYHQQFQEKNREYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQCQTQERYSKEYIEKFRREGNEKEIQRIMVNYEKLKSRISEIVDSKRRLEEDLKKQAADYREIDKRMNSIKPDLIQLRKTRDQYLMWLTQKGVRQKKLNEWLGIKNENQDDQYSMVEDDEDLPHHDERSWKLGNINRIQAEALLRGKRDGTFLVRDSSKAGCYACSVVVDGEVKHCVINKTPTGYGFAEPYNLYNSLKELVLHYQHTSLVQHNDSLNVTLAYPVYGHQRR", "length": 727 }, "evidence": [ { "id": "A0A3Q3ACS4", "url": "https://omabrowser.org/oma/group/A0A3Q3ACS4/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "P23727-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit alpha", "gene_name": "PIK3R1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSAEGYQYRALYDYKKEREEDIDLHLGDILTVNKGSLVALGFSDGQEAKPEEIGWLNGYNETTGERGDFPGTYVEYIGRKKISPPTPKPRPPRPLPVAPGPSKTEADSEQQASTLPDLAEQFAPPDVAPPLLIKLVEAIEKKGLECSTLYRTQSSSNPAELRQLLDCDTASLDLEMFDVHVLADAFKRYLLDLPNPVIPVAVSSELISLAPEVQSSEEYIQLLKKLIRSPSIPHQYWLTLQYLLKHFFKLSQTSSKNLLNARVLSELFSPLLFRFPAASSENTEHLIKIIEILISTEWNERQPAPALPPKPPKPTTVANNGMNNNMSLQDAEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHRDGKYGFSDPLTFNSVVELINHYRNESLAQYNPKLDVKLLYPVSKYQQDQVVKEDNIEAVGKKLHEYNTQFQEKSREYDRLYEDYTRTSQEIQMKRTAIEAFNETIKIFEEQCQTQERYSKEYIEKFKREGNETEIQRIMHNYEKLKSRISEIVDSRRRLEEDLKKQAAEYREIDKRMNSIKPDLIQLRKTRDQYLMWLTQKGVRQKKLNEWLGNENTEDQYSLVEDDEDLPHHDEKTWNVGSSNRNKAENLLRGKRDGTFLVRESSKQGCYACSVVVDGEVKHCVINKTATGYGFAEPYNLYSSLKELVLHYQHTSLVQHNDSLNVTLAYPVYAQQRR", "length": 724 }, "evidence": [ { "id": "A0A3Q3ACS4", "url": "https://omabrowser.org/oma/group/A0A3Q3ACS4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P26450-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit alpha", "gene_name": "Pik3r1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAEGYQYRALYDYKKEREEDIDLHLGDILTVNKGSLVALGFSDGQEARPEDIGWLNGYNETTGERGDFPGTYVEYIGRKRISPPTPKPRPPRPLPVAPGSSKTEADTEQQALPLPDLAEQFAPPDVAPPLLIKLLEAIEKKGLECSTLYRTQSSSNPAELRQLLDCDAASVDLEMIDVHVLADAFKRYLADLPNPVIPVAVYNEMMSLAQELQSPEDCIQLLKKLIRLPNIPHQCWLTLQYLLKHFFKLSQASSKNLLNARVLSEIFSPVLFRFPAASSDNTEHLIKAIEILISTEWNERQPAPALPPKPPKPTTVANNSMNNNMSLQDAEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHRDGKYGFSDPLTFNSVVELINHYRNESLAQYNPKLDVKLLYPVSKYQQDQVVKEDNIEAVGKKLHEYNTQFQEKSREYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQCQTQERYSKEYIEKFKREGNEKEIQRIMHNHDKLKSRISEIIDSRRRLEEDLKKQAAEYREIDKRMNSIKPDLIQLRKTRDQYLMWLTQKGVRQKKLNEWLGNENTEDQYSLVEDDEDLPHHDEKTWNVGSSNRNKAENLLRGKRDGTFLVRESSKQGCYACSVVVDGEVKHCVINKTATGYGFAEPYNLYSSLKELVLHYQHTSLVQHNDSLNVTLAYPVYAQQRR", "length": 724 }, "evidence": [ { "id": "A0A3Q3ACS4", "url": "https://omabrowser.org/oma/group/A0A3Q3ACS4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P27986-1", "protein_name": "Phosphatidylinositol 3-kinase 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"pmid": "" }, { "name": "natural killer cell mediated cytotoxicity", "id": "GO:0042267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042267", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q3ACS4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3ACS4" } ], "pmid": "" }, { "name": "regulation of toll-like receptor 4 signaling pathway", "id": "GO:0034143", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034143", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q3ACS4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3ACS4" } ], "pmid": "" }, { "name": "T follicular helper cell differentiation", "id": "GO:0061470", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061470", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q3ACS4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3ACS4" } ], "pmid": "" }, { "name": "positive regulation of focal adhesion disassembly", "id": "GO:0120183", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120183", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q3ACS4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3ACS4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 14, "go_terms": [ { "name": "kinase activator activity", "id": "GO:0019209", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019209", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q3ACS4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3ACS4" } ], "pmid": "" }, { "name": "phosphotyrosine residue binding", "id": "GO:0001784", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001784", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q3ACS4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3ACS4" } ], "pmid": "" }, { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q3ACS4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3ACS4" } ], "pmid": "" }, { "name": "insulin receptor binding", "id": "GO:0005158", "url": 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"n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A1D5PUP4-1", "uniprot_ac": "A0A1D5PUP4", "uniprot_id": "RECK_CHICK", "mass": { "chemical_mass": 105701.0, "monoisotopic_mass": 105701.0 }, "refseq": { "ac": "XP_418897", "name": "reversion-inducing cysteine-rich protein with Kazal motifs isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418897" }, "gene_names": [ { "name": "RECK", "type": "recommended", "evidence": [ { "id": "A0A1D5PUP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUP4" } ] }, { "name": "RECK", "type": "synonym", "evidence": [ { "id": "XP_418897", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418897" } ] } ], "protein_names": [ { "name": "Reversion-inducing cysteine-rich protein with Kazal motifs", "type": "recommended", "evidence": [ { "id": "A0A1D5PUP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUP4/entry#names_and_taxonomy" } ] }, { "name": "reversion-inducing cysteine-rich protein with Kazal motifs isoform X1", "type": "synonym", "evidence": [ { "id": "XP_418897", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418897" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052533.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_418897.4. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_418897", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418897" } ] }, { "annotation": "Functions together with ADGRA2 to enable brain endothelial cells to selectively respond to Wnt7 signals (WNT7A or WNT7B) (By similarity). Plays a key role in Wnt7-specific responses: required for central nervous system (CNS) angiogenesis and blood-brain barrier regulation (By similarity). Acts as a Wnt7-specific coactivator of canonical Wnt signaling by decoding Wnt ligands: acts by interacting specifically with the disordered linker region of Wnt7, thereby conferring ligand selectivity for Wnt7. ADGRA2 is then required to deliver RECK-bound Wnt7 to frizzled by assembling a higher-order RECK-ADGRA2-Fzd-LRP5-LRP6 complex. Also acts as a serine protease inhibitor (By similarity).", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PUP4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUP4#function" }, { "database": "UniProtKB", "id": "Q9Z0J1", "url": "https://www.uniprot.org/uniprotkb/Q9Z0J1#function" }, { "database": "UniProtKB", "id": "O95980", "url": "https://www.uniprot.org/uniprotkb/O95980#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PUP4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUP4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RECK", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUP4", "locus": { "chromosome": "2", "start_pos": 55727275, "end_pos": 55652111, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010007982", "url": "https://www.ensembl.org/id/ENSGALG00010007982" } ] } } ], "crossref": [ { "id": "A0A1D5PUP4", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PUP4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000036829", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000036829", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "420804", "url": "https://www.ncbi.nlm.nih.gov/gene/420804", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002350", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002350", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036058", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036058", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039016", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039016", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055134", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055134", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056976", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056976", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056977", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056977", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056978", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056978", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:420804", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420804", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A1D5PUP4", "url": "https://www.orthodb.org/?gene=A0A1D5PUP4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13487", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13487", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13487:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13487:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07648", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07648", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22955", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22955", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22961", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22961", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23298", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23298", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23332", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23332", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25027", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25027", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25028", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25028", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:A0A1D5PUP4", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:A0A1D5PUP4", "database": "PRO", "categories": [ "Protein" ] }, { "id": "R-GGA-163125", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-163125", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_418897", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418897", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PUP4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUP4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PUP4-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUP4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAAVAAWPWALFCLAAVPPLLSPGAAGLSCCYHAKDNLMCRDVCEQILSSKSDSRLKHLLQRAPEYCPESMGEVWGCINSSLPGVLKKSDGWVGLGCCELAIAVECRQACKQASSKNDILKVCRKEYENALFSCINRNEMGSICCSYAGHHTNCREYCQAIFRTDSSPGPSQIKAVENYCASISPQLIHCVNNYTQSYPMRNPTDSLYCCDRAEDYACQTACKRILMSMKTELEIVDGLIEGCKTMPLPQDPLWQCFLESSRSVHPGVTVHPPPSTGLDGAKLHCCSKANSSTCRELCTKLYSTSWGSSQSWQEFDRFCEYNAVEVSMLTCLADVREPCQLGCRNLSYCTNFNNRPTELFRSCNSQSDQGAMNDMKLWEKGSIKMPFINIPVLDINKCQPEMWKAIACSLQIKPCHSKSRGSIICKSDCVEILKKCGDHNKFPEGHTAESICELLSPTDDLENCIPLDTYLSPSSLGNIVEDVTHPCNPNPCAANQLCEVNRKGCQSGELCLPYLCVPGCKLGEASDFIVRQGTLIQVPSSAGDVGCYKICTCGHTGLLENCVEMHCVDLQKSCIVGGQKKSHGTSFNIDCNVCSCFAGNLICSTRQCLTEHSSEDERQKFTGLPCNCVDQFVPVCGQNGRTYPSACIARCVGLQDNQFEFGSCISKDPCNPNPCSKNQRCIPKKQVCLTSFGKFECSQHECVPRQLNCDQTQDPVCDTDSVEYSNVCTLYQKGKNLAYRGPCQPFCKSVEPVCGHNGETYSSVCAAYSDRVAVDYYGHCQAVGVLSDYGFHTECAFVKCPQLSATGCKPVIAPGACCPLCAGMLRILYDKDKLDNFARVTNKKPITVLDILEKLRLHVSVPQCDVFGYLSIESEIVILIIPVDQKPKPLQIEACNKEAEKIESLINSDSPTLASHVPLSALIASQVQVSFSISSPSVKVGPVLHCLFISFSFTLLKLMDYI", "length": 963, "header": "sp|A0A1D5PUP4-1|RECK_CHICK Isoform 1 of Reversion-inducing cysteine-rich protein with Kazal motifs OS=Gallus gallus OX=9031 GN=RECK PE=1 SV=1 CANONICAL=A0A1D5PUP4-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PUP4-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUP4/entry#A0A1D5PUP4-1", "sequence": { "sequence": "MAAAVAAWPWALFCLAAVPPLLSPGAAGLSCCYHAKDNLMCRDVCEQILSSKSDSRLKHLLQRAPEYCPESMGEVWGCINSSLPGVLKKSDGWVGLGCCELAIAVECRQACKQASSKNDILKVCRKEYENALFSCINRNEMGSICCSYAGHHTNCREYCQAIFRTDSSPGPSQIKAVENYCASISPQLIHCVNNYTQSYPMRNPTDSLYCCDRAEDYACQTACKRILMSMKTELEIVDGLIEGCKTMPLPQDPLWQCFLESSRSVHPGVTVHPPPSTGLDGAKLHCCSKANSSTCRELCTKLYSTSWGSSQSWQEFDRFCEYNAVEVSMLTCLADVREPCQLGCRNLSYCTNFNNRPTELFRSCNSQSDQGAMNDMKLWEKGSIKMPFINIPVLDINKCQPEMWKAIACSLQIKPCHSKSRGSIICKSDCVEILKKCGDHNKFPEGHTAESICELLSPTDDLENCIPLDTYLSPSSLGNIVEDVTHPCNPNPCAANQLCEVNRKGCQSGELCLPYLCVPGCKLGEASDFIVRQGTLIQVPSSAGDVGCYKICTCGHTGLLENCVEMHCVDLQKSCIVGGQKKSHGTSFNIDCNVCSCFAGNLICSTRQCLTEHSSEDERQKFTGLPCNCVDQFVPVCGQNGRTYPSACIARCVGLQDNQFEFGSCISKDPCNPNPCSKNQRCIPKKQVCLTSFGKFECSQHECVPRQLNCDQTQDPVCDTDSVEYSNVCTLYQKGKNLAYRGPCQPFCKSVEPVCGHNGETYSSVCAAYSDRVAVDYYGHCQAVGVLSDYGFHTECAFVKCPQLSATGCKPVIAPGACCPLCAGMLRILYDKDKLDNFARVTNKKPITVLDILEKLRLHVSVPQCDVFGYLSIESEIVILIIPVDQKPKPLQIEACNKEAEKIESLINSDSPTLASHVPLSALIASQVQVSFSISSPSVKVGPVLHCLFISFSFTLLKLMDYI", "length": 963, "header": "sp|A0A1D5PUP4-1|RECK_CHICK Isoform 1 of Reversion-inducing cysteine-rich protein with Kazal motifs OS=Gallus gallus OX=9031 GN=RECK PE=1 SV=1 CANONICAL=A0A1D5PUP4-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 194, "start_aa": "Asn", "end_pos": 194, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn194", "evidence": [ { "id": "A0A1D5PUP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUP4#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 291, "start_aa": "Asn", "end_pos": 291, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn291", "evidence": [ { "id": "A0A1D5PUP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUP4#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 346, "start_aa": "Asn", "end_pos": 346, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn346", "evidence": [ { "id": "A0A1D5PUP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUP4#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 80, "start_aa": "Asn", "end_pos": 80, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn80", "evidence": [ { "id": "A0A1D5PUP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUP4#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "Sequence and comparative analysis of the chicken genome provide unique perspectives on vertebrate evolution.", "journal": "Nature", "date": "2004", "authors": "", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PUP4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUP4" } ], "reference": [ { "type": "PubMed", "id": "15592404", "url": "https://glygen.org/publication/PubMed/15592404" } ] }, { "title": "GDE2 promotes neurogenesis by glycosylphosphatidylinositol-anchor cleavage of RECK.", "journal": "Science (New York, N.Y.)", "date": "2013", "authors": "Park S, Lee C, Sabharwal P, Zhang M, Meyers CL, Sockanathan S", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PUP4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUP4" } ], "reference": [ { "type": "PubMed", "id": "23329048", "url": "https://glygen.org/publication/PubMed/23329048" } ] } ], "pathway": [ { "id": "gga:420804", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420804", "resource": "KEGG Pathway" }, { "id": "R-GGA-163125", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-163125", "resource": "Reactome", "description": "Post-translational modification: synthesis of GPI-anchored proteins" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "serine-type endopeptidase inhibitor activity", "id": "GO:0004867", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004867", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PUP4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUP4" } ], "pmid": "" }, { "name": "coreceptor activity", "id": "GO:0015026", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015026", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PUP4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUP4" } ], "pmid": "" }, { "name": "endopeptidase inhibitor activity", "id": "GO:0004866", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004866", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PUP4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUP4" } ], "pmid": "" }, { "name": "metalloendopeptidase inhibitor activity", "id": "GO:0008191", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008191", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PUP4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUP4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PUP4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUP4" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PUP4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUP4" } ], "pmid": "" }, { "name": "Wnt signalosome", "id": "GO:1990909", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990909", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PUP4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUP4" } ], "pmid": "" }, { "name": "side of membrane", "id": "GO:0098552", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098552", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PUP4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUP4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 8, "go_terms": [ { "name": "extracellular matrix organization", "id": "GO:0030198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030198", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PUP4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUP4" } ], "pmid": "" }, { "name": "regulation of extracellular matrix organization", "id": "GO:1903053", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903053", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PUP4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUP4" } ], "pmid": "" }, { "name": "blood vessel maturation", "id": "GO:0001955", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001955", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PUP4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUP4" } ], "pmid": "" }, { "name": "canonical Wnt signaling pathway", "id": "GO:0060070", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060070", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PUP4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUP4" } ], "pmid": "" }, { "name": "regulation of canonical Wnt signaling pathway", "id": "GO:0060828", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060828", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PUP4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUP4" } ], "pmid": "" }, { "name": "sprouting angiogenesis", "id": "GO:0002040", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002040", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PUP4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUP4" } ], "pmid": "" }, { "name": "regulation of angiogenesis", "id": "GO:0045765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045765", "evidence": [ { "database": "UniProtKB", "id": 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"table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "O73700-1", "uniprot_ac": "O73700", "uniprot_id": "CAC1D_CHICK", "mass": { "chemical_mass": 249344.0, "monoisotopic_mass": 249344.0 }, "refseq": { "ac": "NP_990365", "name": "voltage-dependent L-type calcium channel subunit alpha-1D", "summary": "This gene encodes a member of the voltage-dependent calcium channel protein subunit family. The cDNA for this gene was cloned from hair cells of the cochlea in the chicken inner ear. Study of the similar transmembrane protein in deficient mice reported impaired cardiac function and deafness, suggesting that the encoded protein is required for normal hearing and pacemaker activity in the heart. [provided by RefSeq, Aug 2012]. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript from the same strain was available for the full length of the gene. The extent of this transcript is supported by transcript alignments and orthologous data.", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990365" }, "gene_names": [ { "name": "CACNA1D", "type": "recommended", "evidence": [ { "id": "O73700", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O73700" } ] }, { "name": "CACNA1D", "type": "synonym", "evidence": [ { "id": "NP_990365", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990365" } ] } ], "protein_names": [ { "name": "Voltage-dependent L-type calcium channel subunit alpha-1D", "type": "recommended", "evidence": [ { "id": "O73700", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O73700/entry#names_and_taxonomy" } ] }, { "name": "CHCACHA1D", "type": "synonym", "evidence": [ { "id": "NP_990365", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990365" }, { "id": "O73700", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O73700/entry#names_and_taxonomy" } ] }, { "name": "L-type voltage-gated calcium channel alpha1D subunit ChCaChA1D", "type": "synonym", "evidence": [ { "id": "NP_990365", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990365" } ] }, { "name": "Voltage-gated calcium channel subunit alpha Cav1.3", "type": "synonym", "evidence": [ { "id": "O73700", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O73700/entry#names_and_taxonomy" } ] }, { "name": "calcium channel, voltage-dependent, L type, alpha 1D subunit", "type": "synonym", "evidence": [ { "id": "NP_990365", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990365" } ] }, { "name": "voltage-dependent L-type calcium channel subunit alpha-1D", "type": "synonym", "evidence": [ { "id": "NP_990365", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990365" } ] }, { "name": "voltage-gated calcium channel subunit alpha Cav1.3", "type": "synonym", "evidence": [ { "id": "NP_990365", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990365" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AF027602.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN05341171 [ECO:0000348] ##Evidence-Data-END## REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from JAENSK010000252.1. On Jan 18, 2005 this sequence version replaced XP_429273.1. This gene encodes a member of the voltage-dependent calcium channel protein subunit family. The cDNA for this gene was cloned from hair cells of the cochlea in the chicken inner ear. Study of the similar transmembrane protein in deficient mice reported impaired cardiac function and deafness, suggesting that the encoded protein is required for normal hearing and pacemaker activity in the heart. [provided by RefSeq, Aug 2012]. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript from the same strain was available for the full length of the gene. The extent of this transcript is supported by transcript alignments and orthologous data.", "evidence": [ { "database": "RefSeq", "id": "NP_990365", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990365" } ] }, { "annotation": "A transient Ca(2+) current produced by the Ca(v)3.1 channel is expressed early in development to initiate spontaneous Ca(2+) spikes. Ca(v)1.3 currents, typical of mature hair cells, appeared later in development.", "evidence": [ { "database": "RefSeq", "id": "NP_990365", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990365" }, { "database": "PubMed", "id": "18025474", "url": "https://glygen.org/publication/PubMed/18025474" } ] }, { "annotation": "Pore-forming, alpha-1C subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents. Mediates influx of calcium ions into the cytoplasm, and thereby triggers calcium release from the sarcoplasm. Plays an important role in excitation-contraction coupling in the heart. Required for normal heart development and normal regulation of heart rhythm. Required for normal contraction of smooth muscle cells in blood vessels and in the intestine. Essential for normal blood pressure regulation via its role in the contraction of arterial smooth muscle cells. Long-lasting (L-type) calcium channels belong to the 'high-voltage activated' (HVA) group.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADG1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADG1#function" }, { "database": "UniProtKB", "id": "ARBA00045450", "url": "https://www.uniprot.org/uniprotkb/ARBA00045450#function" } ] }, { "annotation": "The isoform alpha-1D gives rise to L-type calcium currents. Long-lasting (L-type) calcium channels belong to the 'high-voltage activated' (HVA) group.", "evidence": [ { "database": "UniProtKB", "id": "O73700", "url": "https://www.uniprot.org/uniprotkb/O73700#function" }, { "database": "UniProtKB", "id": "Q01668", "url": "https://www.uniprot.org/uniprotkb/Q01668#function" } ] }, { "annotation": "Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AAN9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAN9#function" }, { "database": "UniProtKB", "id": "RU003808", "url": "https://www.uniprot.org/uniprotkb/RU003808#function" }, { "database": "UniProtKB", "id": "A0A8V1AAP3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAP3#function" }, { "database": 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"categories": [ "Protein Classification" ] }, { "id": "A0A8V1AHW6", "url": "https://www.orthodb.org/?gene=A0A8V1AHW6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "O73700", "url": "https://www.orthodb.org/?gene=O73700", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45628", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45628", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45628:SF11", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45628:SF11", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00520", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00520", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08763", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08763", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16885", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16885", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16905", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16905", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:O73700", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:O73700", "database": "PRO", "categories": [ "Protein" ] }, { "id": "R-GGA-422356", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-422356", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_990365", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990365", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "29671", "url": "https://www.rhea-db.org/rhea/29671", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A1D5PY30", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PY30", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PY30-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PY30-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A5R9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5R9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A5R9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5R9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A5S5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5S5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A5S5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5S5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AAN9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAN9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AAN9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAN9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AAP3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAP3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AAP3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAP3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ADG1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADG1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ADG1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADG1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHW6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHW6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHW6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHW6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "O73700", "url": "https://www.uniprot.org/uniprotkb/O73700", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "O73700-1", "url": "https://www.uniprot.org/uniprotkb/O73700-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "O73700-2", "url": "https://www.uniprot.org/uniprotkb/O73700-2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "O73700-3", "url": "https://www.uniprot.org/uniprotkb/O73700-3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "O73700-4", "url": "https://www.uniprot.org/uniprotkb/O73700-4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "O73700-5", "url": "https://www.uniprot.org/uniprotkb/O73700-5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "O73700-6", "url": "https://www.uniprot.org/uniprotkb/O73700-6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "O73700-7", "url": "https://www.uniprot.org/uniprotkb/O73700-7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "O73700-8", "url": "https://www.uniprot.org/uniprotkb/O73700-8", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQHHQQQQPEQHPEEANYASSTRIPLPGDGPTTQSNSSAPSKQTVLSWQAAIDAARQAKAAQNMNTTTAQPVGSLSQRKRQQYAKSKKQGNTSNSRPPRALFCLSLNNPIRRACISLVEWKPFDIFILLSIFANCVALAVYIPFPEDDSNSTNHNLEKVEYAFLIIFTVETFLKIIAYGLLLHPNAYVRNGWNLLDFVIVVVGLFSVILEQLTKETEGGSHSGGKPGGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFIGKMHKSCFLIDSDILVEEDPAPCAFSGNGRQCVMNGTECKGGWVGPNGGITNFDNFAFAMLTVFQCITMEGWTDVLYWVNDAIGCEWPWIYFVSLIILGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENDEEADEEGKRNRVTLADLMEEKKKSRLSCFGRSSNKHASMPTSETESVNTENVSGEGENPACCGSLCQTISKSKFSRRWRRWNRFNRRKCRAAVKSVTFYWLVIVLVFLNTLTISSEHYNQPDWLTQIQDIANKVLLALFTCEMLVKMYSLGLQAYFVSLFNRFDCFVVCGGIVETILVELEIMSPLGISVFRCVRLLRIFKVTRHWASLSNLVASLLNSMKSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDETQTKRSTFDNFPQALLTVFQILTGEDWNAVMYDGIMAYGGPSSSGMIVCIYFIILFICGNYILLNVFLAIAVDNLADAESLNTAQKEEAEEKERKKNARKESLENKKSEKSEGDQKKPKDSKVTIAEYGEGEDEDKDPYPPCDVPVGEDEEDEEDEPEVPAGPRPRRISELNMKEKITPIPEGSAFFIFSSTNPIRVGCHRLINHHIFTNLILVFIMLSSVSLAAEDPIRSHSFRNNILGYADYVFTSMFTFEIILKMTAFGAFLHKGSFCRNYFNLLDLLVVGVSLVSFGIQSSAISVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIMIVTTLLQFMFACIGVQLFKGKFYKCTDEAKQNPEECRGIYIVYKDGDVDNPMVKERVWQNSDFNFDNVLSAMMALFTVSTFEGWPALLYKAIDSNGENVGPVYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLRRYIPKNPYQYKFWYVVNSTGFEYIMFVLIMLNTLCLAMQHYGQSKLFNDAMDIMNMVFTGVFTVEMVLKLIAFKPKIFVRKKERWLGYFSDAWNTFDSLIVIGSIVDVVLSEADPKPTETVTTDESGNSEDSARISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIAMLFFIYAVIGMQVFGKVAMRDNNQINRNNNFQTFPQAVLLLFRCATGEAWQEIMLACLPGKRCDPESDYNPGEEYTCGSNFAIIYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWSEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVAMNMPLNSDGTVMFNATLFALVRTALKIKTEGNLEQANEELRAVIKKIWKKTSMKLLDQVVPPAGDDEVTVGKFYATFLIQDYFRKFKKRKEQGLVGKYPAKNTTIALQAGLRTLHDIGPEIRRAISCDLQDDEPEENNPDEEEEVYKRNGALFGNHINHISSDRRDSFQQINTTHRPLHVQRPSIPSASDTEKNIYPHTGNSVYHNHHNHNSVGKQVPNSTNANLNNANVSKVVHGKHANFGSHEHRSENGYHSYSRADHEKRRRPSSRRTRYYETYIRSDSGDGRRPTICREERDIRDYCNDDHYLGEQEYYSGEEYYEEDSMLSGNRHVYDYHCRHHCHDSDFERPKGYHHPHGFFEEDDSQTCYDTKRSPRRRLLPPTPASNRRSSFNFECLRRQSSQDDIPLSPNFHHRTALPLHLMQQQVMAVAGLDSSKAHKHSPSRSTRSWATPPATPPNRDHTPYYTPLIQVDRAESTEHMNGSLPSLHRSSWYTDDPDISYRTFTPANLTVPNDFRHKHSDKQRSADSLVEAVLISEGLGRYAKDPKFVSATKHEIADACDMTIDEMESAASNLLNGNISNGTNGDMFPILSRQDYELQDFGPGYSDEEPEPGRYEEDLADEMICITSL", "length": 2190, "header": "sp|O73700-1|CAC1D_CHICK Isoform 1 of Voltage-dependent L-type calcium channel subunit alpha-1D OS=Gallus gallus OX=9031 GN=CACNA1D PE=1 SV=1 CANONICAL=O73700-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PY30-1", "url": "https://www.uniprot.org/uniprotkb/O73700/entry#A0A1D5PY30-1", "sequence": { "sequence": "MQHHQQQQPEQHPEEANYASSTRIPLPGDGPTTQSNSSAPSKQTVLSWQAAIDAARQAKAAQNMNTTTAQPVGSLSQRKRQQYAKSKKQGNTSNSRPPRALFCLSLNNPIRRACISLVEWKPFDIFILLSIFANCVALAVYIPFPEDDSNSTNHNLEKVEYAFLIIFTVETFLKIIAYGLLLHPNAYVRNGWNLLDFVIVVVGLFSVILEQLTKETEGGSHSGGKPGGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFIGKMHKSCFLIDSDILVEEDPAPCAFSGNGRQCVMNGTECKGGWVGPNGGITNFDNFAFAMLTVFQCITMEGWTDVLYWMNDAMGFELPWVYFVSLVIFGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENDEEADEEGKRNTSMPTSETESVNTENVSGEGENPACCGSLCQTISKSKFSRRWRRWNRFNRRKCRAAVKSVTFYWLVIVLVFLNTLTISSEHYNQPDWLTQIQDIANKVLLALFTCEMLVKMYSLGLQAYFVSLFNRFDCFVVCGGIVETILVELEIMSPLGISVFRCVRLLRIFKVTRHWASLSNLVASLLNSMKSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDETQTKRSTFDNFPQALLTVFQILTGEDWNAVMYDGIMAYGGPSSSGMIVCIYFIILFICGNYILLNVFLAIAVDNLADAESLNTAQKEEAEEKERKKNARKESLENKKSEKSEGDQKKPKDSKVTIAEYGEGEDEDKDPYPPCDVPVGEDEEDEEDEPEVPAGPRPRRISELNMKEKITPIPEGSAFFIFSSTNPIRVGCHRLINHHIFTNLILVFIMLSSVSLAAEDPIRSHSFRNNILGYFDYAFTAIFTVEILLKMTAFGAFLHKGSFCRNYFNLLDLLVVGVSLVSFGIQSSAISVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIMIVTTLLQFMFACIGVQLFKGKFYKCTDEAKQNPEECRGIYIVYKDGDVDNPMVKERVWQNSDFNFDNVLSAMMALFTVSTFEGWPALLYKAIDSNGENVGPVYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLRRYIPKNPYQYKFWYVVNSTGFEYIMFVLIMLNTLCLAMQHYGQSKLFNDAMDIMNMVFTGVFTVEMVLKLIAFKPKGYFSDAWNTFDSLIVIGSIVDVVLSEADNSEDSARISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIAMLFFIYAVIGMQVFGKVAMRDNNQINRNNNFQTFPQAVLLLFRCATGEAWQEIMLACLPGKRCDPESDYNPGEEYTCGSNFAIIYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWSEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVAMNMPLNSDGTVMFNATLFALVRTALKIKTEGNLEQANEELRAVIKKIWKKTSMKLLDQVVPPAGDDEVTVGKFYATFLIQDYFRKFKKRKEQGLVGKYPAKNTTIALQAGLRTLHDIGPEIRRAISCDLQDDEPEENNPDEEEEVYKRNGALFGNHINHISSDRRDSFQQINTTHRPLHVQRPSIPSASDTEKNIYPHTGNSVYHNHHNHNSVGKQVPNSTNANLNNANVSKVVHGKHANFGSHEHRSENGYHSYSRADHEKRRRPSSRRSDSGDGRRPTICREERDIRDYCNDDHYLGEQEYYSGEEYYEEDSMLSGNRHVYDYHCRHHCHDSDFERPKGYHHPHGFFEEDDSQTCYDTKRSPRRRLLPPTPASNRRSSFNFECLRRQSSQDDIPLSPNFHHRTALPLHLMQQQVMAVAGLDSSKAHKHSPSRSTRSWATPPATPPNRDHTPYYTPLIQVDRAESTEHMNGSLPSLHRSSWYTDDPDISYRTFTPANLTVPNDFRHKHSDKQRSADSLVEAVLISEGLGRYAKDPKFVSATKHEIADACDMTIDEMESAASNLLNGNISNGTNGDMFPILSRQDYELQDFGPGYSDEEPEPGRYEEDLADEMICITSL", "length": 2132, "header": "tr|A0A1D5PY30-1|CAC1D_CHICK Computationally mapped isoform of Voltage-dependent L-type calcium channel subunit alpha-1D OS=Gallus gallus OX=9031 GN=CACNA1D PE=1 SV=2 CANONICAL=O73700-1" }, "locus": { "chromosome": "12", "start_pos": 7395709, "end_pos": 7232067, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067515.1", "url": "https://www.ensembl.org/id/ENSGALT00010067515.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041258.1", "url": "https://www.ensembl.org/id/ENSGALP00010041258.1" } ] } }, { "isoform_ac": "A0A8V1A5R9-1", "url": "https://www.uniprot.org/uniprotkb/O73700/entry#A0A8V1A5R9-1", "sequence": { "sequence": "ASHHQEANYASSTRIPLPGDGPTTQSNSSAPSKQTVLSWQAAIDAARQAKAAQNMNTTTAQPVGSLSQRKRQQYAKSKKQGNTSNSRPPRALFCLSLNNPIRRACISLVEWKPFDIFILLSIFANCVALAVYIPFPEDDSNSTNHNLEKVEYAFLIIFTVETFLKIIAYGLLLHPNAYVRNGWNLLDFVIVVVGLFSVILEQLTKETEGGSHSGGKPGGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFIGKMHKSCFLIDSDILVEEDPAPCAFSGNGRQCVMNGTECKGGWVGPNGGITNFDNFAFAMLTVFQCITMEGWTDVLYWVNDAIGCEWPWIYFVSLIILGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENDEEADEEGKRNRVTLADLMEEKKKSRLSCFGRSSNKHASMPTSETESVNTENVSGEGENPACCGSLCQTISKSKFSRRWRRWNRFNRRKCRAAVKSVTFYWLVIVLVFLNTLTISSEHYNQPDWLTQIQDIANKVLLALFTCEMLVKMYSLGLQAYFVSLFNRFDCFVVCGGIVETILVELEIMSPLGISVFRCVRLLRIFKVTRHWASLSNLVASLLNSMKSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDETQTKRSTFDNFPQALLTVFQILTGEDWNAVMYDGIMAYGGPSSSGMIVCIYFIILFICGNYILLNVFLAIAVDNLADAESLNTAQKEEAEEKERKKNARKESLENKKSEKSEGDQKKPKDSKVTIAEYGEGEDEDKDPYPPCDVPVGEDEEDEEDEPEVPAGPRPRRISELNMKEKITPIPEGSAFFIFSSTNPIRVGCHRLINHHIFTNLILVFIMLSSVSLAAEDPIRSHSFRNNILGYADYVFTSMFTFEIILKMTAFGAFLHKGSFCRNYFNLLDLLVVGVSLVSFGIQSSAISVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIMIVTTLLQFMFACIGVQLFKGKFYKCTDEAKQNPEECRGIYIVYKDGDVDNPMVKERVWQNSDFNFDNVLSAMMALFTVSTFEGWPALLYKAIDSNGENVGPVYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLRRYIPKNPYQYKFWYVVNSTGFEYIMFVLIMLNTLCLAMQHYGQSKLFNDAMDIMNMVFTGVFTVEMVLKLIAFKPKIFVRKKERWLGYFSDAWNTFDSLIVIGSIVDVVLSEADVSIPQLTFPSPYFSFSNSEDSARISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIAMLFFIYAVIGMQVFGKVAMRDNNQINRNNNFQTFPQAVLLLFRCATGEAWQEIMLACLPGKRCDPESDYNPGEEYTCGSNFAIIYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWSEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVAMNMPLNSDGTVMFNATLFALVRTALKIKTEGNLEQANEELRAVIKKIWKKTSMKLLDQVVPPAGDDEVTVGKFYATFLIQDYFRKFKKRKEQGLVGKYPAKNTTIALQAGLRTLHDIGPEIRRAISCDLQDDEPEENNPDEEEEVYKRNGALFGNHINHISSDRRDSFQQINTTHRPLHVQRPSIPSASDTEKNIYPHTGNSVYHNHHNHNSVGKQVPNSTNANLNNANVSKVVHGKHANFGSHEHRSENGYHSYSRADHEKRRRPSSRRTRYYETYIRSDSGDGRRPTICREERDIRDYCNDDHYLGEQEYYSGEEYYEEDSMLSGNRHVYDYHCRHHCHDSDFERPKGYHHPHGFFEEDDSQTCYDTKRSPRRRLLPPTPASNRRSSFNFECLRRQSSQDDIPLSPNFHHRTALPLHLMQQQVMAVAGLDSSKAHKHSPSRSTRSWATPPATPPNRDHTPYYTPLIQVDRAESTEHMNGSLPSLHRSSWYTDDPDISYRTFTPANLTVPNDFRHKHSDKQRSADSLVEAVLISEGLGRYAKDPKFVSATKHEIADACDMTIDEMESAASNLLNGNISNGTNGDMFPILSRQDYELQDFGPGYSDEEPEPGRYEEDLADEMICITSL", "length": 2184, "header": "tr|A0A8V1A5R9-1|CAC1D_CHICK Computationally mapped isoform of Voltage-dependent L-type calcium channel subunit alpha-1D OS=Gallus gallus OX=9031 GN=CACNA1D PE=1 SV=1 CANONICAL=O73700-1" }, "locus": { "chromosome": "12", "start_pos": 7395709, "end_pos": 7233934, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067492.1", "url": "https://www.ensembl.org/id/ENSGALT00010067492.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041244.1", "url": "https://www.ensembl.org/id/ENSGALP00010041244.1" } ] } }, { "isoform_ac": "A0A8V1A5S5-1", "url": "https://www.uniprot.org/uniprotkb/O73700/entry#A0A8V1A5S5-1", "sequence": { "sequence": "MQHHQQQQPEQHPEEANYASSTRIPLPGDGPTTQSNSSAPSKQTVLSWQAAIDAARQAKAAQNMNTTTAQPVGSLSQRKRQQYAKSKKQGNTSNSRPPRALFCLSLNNPIRRACISLVEWKPFDIFILLSIFANCVALAVYIPFPEDDSNSTNHNLEKVEYAFLIIFTVETFLKIIAYGLLLHPNAYVRNGWNLLDFVIVVVGLFSVILEQLTKETEGGSHSGGKPGGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFIGKMHKSCFLIDSDILVEEDPAPCAFSGNGRQCVMNGTECKGGWVGPNGGITNFDNFAFAMLTVFQCITMEGWTDVLYWMNDAMGFELPWVYFVSLVIFGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENDEEADEEGKRNTSMPTSETESVNTENVSGEGENPACCGSLCQTISKSKFSRRWRRWNRFNRRKCRAAVKSVTFYWLVIVLVFLNTLTISSEHYNQPDWLTQIQDIANKVLLALFTCEMLVKMYSLGLQAYFVSLFNRFDCFVVCGGIVETILVELEIMSPLGISVFRCVRLLRIFKVTRHWASLSNLVASLLNSMKSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDETQTKRSTFDNFPQALLTVFQILTGEDWNAVMYDGIMAYGGPSSSGMIVCIYFIILFICGNYILLNVFLAIAVDNLADAESLNTAQKEEAEEKERKKNARKESLENKKSEKSEGDQKKPKDSKVTIAEYGEGEDEDKDPYPPCDVPVGEDEEDEEDEPEVPAGPRPRRISELNMKEKITPIPEGSAFFIFSSTNPIRVGCHRLINHHIFTNLILVFIMLSSVSLAAEDPIRSHSFRNNILGYFDYAFTAIFTVEILLKMTAFGAFLHKGSFCRNYFNLLDLLVVGVSLVSFGIQSSAISVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIMIVTTLLQFMFACIGVQLFKGKFYKCTDEAKQNPEECRGIYIVYKDGDVDNPMVKERVWQNSDFNFDNVLSAMMALFTVSTFEGWPALLYKAIDSNGENVGPVYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLRRYIPKNPYQYKFWYVVNSTGFEYIMFVLIMLNTLCLAMQHYGQSKLFNDAMDIMNMVFTGVFTVEMVLKLIAFKPKHYFTDAWNTFDALIVVGSVVDIAITEVNPKPTETVTTDESGNSEDSARISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIAMLFFIYAVIGMQVFGKVAMRDNNQINRNNNFQTFPQAVLLLFRCATGEAWQEIMLACLPGKRCDPESDYNPGEEYTCGSNFAIIYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWSEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVAMNMPLNSDGTVMFNATLFALVRTALKIKTEGNLEQANEELRAVIKKIWKKTSMKLLDQVVPPAGDDEVTVGKFYATFLIQDYFRKFKKRKEQGLVGKYPAKNTTIALQAGLRTLHDIGPEIRRAISCDLQDDEPEENNPDEEEEVYKRNGALFGNHINHISSDRRDSFQQINTTHRPLHVQRPSIPSASDTEKNIYPHTGNSVYHNHHNHNSVGKQVPNSTNANLNNANVSKVVHGKHANFGSHEHRSENGYHSYSRADHEKRRRPSSRRTRYYETYIRSDSGDGRRPTICREERDIRDYCNDDHYLGEQEYYSGEEYYEEDSMLSGNRHVYDYHCRHHCHDSDFERPKGYHHPHGFFEEDDSQTCYDTKRSPRRRLLPPTPASNRRSSFNFECLRRQSSQDDIPLSPNFHHRTALPLHLMQQQVMAVAGLDSSKAHKHSPSRSTRSWATPPATPPNRDHTPYYTPLIQVDRAESTEHMNGSLPSLHRSSWYTDDPDISYRTFTPANLTVPNDFRHKHSDKQRSADSLVEAVLISEGLGRYAKDPKFVSATKHEIADACDMTIDEMESAASNLLNGNISNGTNGDMFPILSRQDYELQDFGPGYSDEEPEPGRYEEDLADEMICITSL", "length": 2154, "header": "tr|A0A8V1A5S5-1|CAC1D_CHICK Computationally mapped isoform of Voltage-dependent L-type calcium channel subunit alpha-1D OS=Gallus gallus OX=9031 GN=CACNA1D PE=1 SV=1 CANONICAL=O73700-1" }, "locus": { "chromosome": "12", "start_pos": 7395709, "end_pos": 7232067, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067509.1", "url": "https://www.ensembl.org/id/ENSGALT00010067509.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041252.1", "url": "https://www.ensembl.org/id/ENSGALP00010041252.1" } ] } }, { "isoform_ac": "A0A8V1AAN9-1", "url": "https://www.uniprot.org/uniprotkb/O73700/entry#A0A8V1AAN9-1", "sequence": { "sequence": "MQHHQQQQPEQHPEEANYASSTRIPLPGDGPTTQSNSSAPSKQTVLSWQAAIDAARQAKAAQNMNTTTAQPVGSLSQRKRQQYAKSKKQGNTSNSRPPRALFCLSLNNPIRRACISLVEWKPFDIFILLSIFANCVALAVYIPFPEDDSNSTNHNLEKVEYAFLIIFTVETFLKIIAYGLLLHPNAYVRNGWNLLDFVIVVVGLFSVILEQLTKETEGGSHSGGKPGGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFIGKMHKSCFLIDSDILVEEDPAPCAFSGNGRQCVMNGTECKGGWVGPNGGITNFDNFAFAMLTVFQCITMEGWTDVLYWMNDAMGFELPWVYFVSLVIFGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENDEEADEEGKRNTSMPTSETESVNTENVSGEGENPACCGSLCQTISKSKFSRRWRRWNRFNRRKCRAAVKSVTFYWLVIVLVFLNTLTISSEHYNQPDWLTQIQDIANKVLLALFTCEMLVKMYSLGLQAYFVSLFNRFDCFVVCGGIVETILVELEIMSPLGISVFRCVRLLRIFKVTRHWASLSNLVASLLNSMKSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDETQTKRSTFDNFPQALLTVFQILTGEDWNAVMYDGIMAYGGPSSSGMIVCIYFIILFICGNYILLNVFLAIAVDNLADAESLNTAQKEEAEEKERKKNARKESLENKKSEKSEGDQKKPKDSKVTIAEYGEGEDEDKDPYPPCDVPVGEDEEDEEDEPEVPAGPRPRRISELNMKEKITPIPEGSAFFIFSSTNPIRVGCHRLINHHIFTNLILVFIMLSSVSLAAEDPIRSHSFRNNILGYFDYAFTAIFTVEILLKMTAFGAFLHKGSFCRNYFNLLDLLVVGVSLVSFGIQSSAISVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIMIVTTLLQFMFACIGVQLFKGKFYKCTDEAKQNPEECRGIYIVYKDGDVDNPMVKERVWQNSDFNFDNVLSAMMALFTVSTFEGWPALLYKAIDSNGENVGPVYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLRRYIPKNPYQYKFWYVVNSTGFEYIMFVLIMLNTLCLAMQHYGQSKLFNDAMDIMNMVFTGVFTVEMVLKLIAFKPKHYFTDAWNTFDALIVVGSVVDIAITEVNNSEDSARISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIAMLFFIYAVIGMQVFGKVAMRDNNQINRNNNFQTFPQAVLLLFRCATGEAWQEIMLACLPGKRCDPESDYNPGEEYTCGSNFAIIYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWSEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVAMNMPLNSDGTVMFNATLFALVRTALKIKTEGNLEQANEELRAVIKKIWKKTSMKLLDQVVPPAGDDEVTVGKFYATFLIQDYFRKFKKRKEQGLVGKYPAKNTTIALQAGLRTLHDIGPEIRRAISCDLQDDEPEENNPDEEEEVYKRNGALFGNHINHISSDRRDSFQQINTTHRPLHVQRPSIPSASDTEKNIYPHTGNSVYHNHHNHNSVGKQVPNSTNANLNNANVSKVVHGKHANFGSHEHRSENGYHSYSRADHEKRRRPSSRRTRYYETYIRSDSGDGRRPTICREERDIRDYCNDDHYLGEQEYYSGEEYYEEDSMLSGNRHVYDYHCRHHCHDSDFERPKGYHHPHGFFEEDDSQTCYDTKRSPRRRLLPPTPASNRRSSFNFECLRRQSSQDDIPLSPNFHHRTALPLHLMQQQVMAVAGLDSSKAHKHSPSRSTRSWATPPATPPNRDHTPYYTPLIQVDRAESTEHMNGSLPSLHRSSWYTDDPDISYRTFTPANLTVPNDFRHKHSDKQRSADSLVEAVLISEGLGRYAKDPKFVSATKHEIADACDMTIDEMESAASNLLNGNISNGTNGDMFPILSRQDYELQDFGPGYSDEEPEPGRYEEDLADEMICITSL", "length": 2141, "header": "tr|A0A8V1AAN9-1|CAC1D_CHICK Computationally mapped isoform of Voltage-dependent L-type calcium channel subunit alpha-1D OS=Gallus gallus OX=9031 GN=CACNA1D PE=1 SV=1 CANONICAL=O73700-1" }, "locus": { "chromosome": "12", "start_pos": 7395709, "end_pos": 7232067, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067511.1", "url": "https://www.ensembl.org/id/ENSGALT00010067511.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041254.1", "url": "https://www.ensembl.org/id/ENSGALP00010041254.1" } ] } }, { "isoform_ac": "A0A8V1AAP3-1", "url": "https://www.uniprot.org/uniprotkb/O73700/entry#A0A8V1AAP3-1", "sequence": { "sequence": "MQHHQQQQPEQHPEEANYASSTRIPLPGDGPTTQSNSSAPSKQTVLSWQAAIDAARQAKAAQNMNTTTAQPVGSLSQRKRQQYAKSKKQGNTSNSRPPRALFCLSLNNPIRRACISLVEWKPFDIFILLSIFANCVALAVYIPFPEDDSNSTNHNLEKVEYAFLIIFTVETFLKIIAYGLLLHPNAYVRNGWNLLDFVIVVVGLFSVILEQLTKETEGGSHSGGKPGGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFIGKMHKSCFLIDSDILVEEDPAPCAFSGNGRQCVMNGTECKGGWVGPNGGITNFDNFAFAMLTVFQCITMEGWTDVLYWMNDAMGFELPWVYFVSLVIFGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENDEEADEEGKRNTSMPTSETESVNTENVSGEGENPACCGSLCQTISKSKFSRRWRRWNRFNRRKCRAAVKSVTFYWLVIVLVFLNTLTISSEHYNQPDWLTQIQDIANKVLLALFTCEMLVKMYSLGLQAYFVSLFNRFDCFVVCGGIVETILVELEIMSPLGISVFRCVRLLRIFKVTRHWASLSNLVASLLNSMKSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDETQTKRSTFDNFPQALLTVFQILTGEDWNAVMYDGIMAYGGPSSSGMIVCIYFIILFICGNYILLNVFLAIAVDNLADAESLNTAQKEEAEEKERKKNARKESLENKKSEKSEGDQKKPKDSKVTIAEYGEGEDEDKDPYPPCDVPVGEDEEDEEDEPEVPAGPRPRRISELNMKEKITPIPEGSAFFIFSSTNPIRVGCHRLINHHIFTNLILVFIMLSSVSLAAEDPIRSHSFRNNILGYFDYAFTAIFTVEILLKMTAFGAFLHKGSFCRNYFNLLDLLVVGVSLVSFGIQSSAISVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIMIVTTLLQFMFACIGVQLFKGKFYKCTDEAKQNPEECRGIYIVYKDGDVDNPMVKERVWQNSDFNFDNVLSAMMALFTVSTFEGWPALLYKAIDSNGENVGPVYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLRRYIPKNPYQYKFWYVVNSTGFEYIMFVLIMLNTLCLAMQHYGQSKLFNDAMDIMNMVFTGVFTVEMVLKLIAFKPKNSEDSARISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIAMLFFIYAVIGMQVFGKVAMRDNNQINRNNNFQTFPQAVLLLFRCATGEAWQEIMLACLPGKRCDPESDYNPGEEYTCGSNFAIIYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWSEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVAMNMPLNSDGTVMFNATLFALVRTALKIKTEGNLEQANEELRAVIKKIWKKTSMKLLDQVVPPAGDDEVTVGKFYATFLIQDYFRKFKKRKEQGLVGKYPAKNTTIALQAGLRTLHDIGPEIRRAISCDLQDDEPEENNPDEEEEVYKRNGALFGNHINHISSDRRDSFQQINTTHRPLHVQRPSIPSASDTEKNIYPHTGNSVYHNHHNHNSVGKQVPNSTNANLNNANVSKVVHGKHANFGSHEHRSENGYHSYSRADHEKRRRPSSRRTRYYETYIRSDSGDGRRPTICREERDIRDYCNDDHYLGEQEYYSGEEYYEEDSMLSGNRHVYDYHCRHHCHDSDFERPKGYHHPHGFFEEDDSQTCYDTKRSPRRRLLPPTPASNRRSSFNFECLRRQSSQDDIPLSPNFHHRTALPLHLMQQQVMAVAGLDSSKAHKHSPSRSTRSWATPPATPPNRDHTPYYTPLIQVDRAESTEHMNGSLPSLHRSSWYTDDPDISYRTFTPANLTVPNDFRHKHSDKQRSADSLVEAVLISEGLGRYAKDPKFVSATKHEIADACDMTIDEMESAASNLLNGNISNGTNGDMFPILSRQDYELQDFGPGYSDEEPEPGRYEEDLADEMICITSL", "length": 2113, "header": "tr|A0A8V1AAP3-1|CAC1D_CHICK Computationally mapped isoform of Voltage-dependent L-type calcium channel subunit alpha-1D OS=Gallus gallus OX=9031 GN=CACNA1D PE=1 SV=1 CANONICAL=O73700-1" }, "locus": { "chromosome": "12", "start_pos": 7395709, "end_pos": 7232067, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067516.1", "url": "https://www.ensembl.org/id/ENSGALT00010067516.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041259.1", "url": "https://www.ensembl.org/id/ENSGALP00010041259.1" } ] } }, { "isoform_ac": "A0A8V1ADG1-1", "url": "https://www.uniprot.org/uniprotkb/O73700/entry#A0A8V1ADG1-1", "sequence": { "sequence": "MQHHQQQQPEQHPEEANYASSTRIPLPGDGPTTQSNSSAPSKQTVLSWQAAIDAARQAKAAQNMNTTTAQPVGSLSQRKRQQYAKSKKQGNTSNSRPPRALFCLSLNNPIRRACISLVEWKPFDIFILLSIFANCVALAVYIPFPEDDSNSTNHNLEKVEYAFLIIFTVETFLKIIAYGLLLHPNAYVRNGWNLLDFVIVVVGLFSVILEQLTKETEGGSHSGGKPGGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFIGKMHKSCFLIDSDILVEEDPAPCAFSGNGRQCVMNGTECKGGWVGPNGGITNFDNFAFAMLTVFQCITMEGWTDVLYWMNDAMGFELPWVYFVSLVIFGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENDEEADEEGKRNTSMPTSETESVNTENVSGEGENPACCGSLCQTISKSKFSRRWRRWNRFNRRKCRAAVKSVTFYWLVIVLVFLNTLTISSEHYNQPDWLTQIQDIANKVLLALFTCEMLVKMYSLGLQAYFVSLFNRFDCFVVCGGIVETILVELEIMSPLGISVFRCVRLLRIFKVTRHWASLSNLVASLLNSMKSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDETQTKRSTFDNFPQALLTVFQILTGEDWNAVMYDGIMAYGGPSSSGMIVCIYFIILFICGNYILLNVFLAIAVDNLADAESLNTAQKEEAEEKERKKNARKESLENKKSEKSEGDQKKPKDSKVTIAEYGEGEDEDKDPYPPCDVPVGEDEEDEEDEPEVPAGPRPRRISELNMKEKITPIPEGSAFFIFSSTNPIRVGCHRLINHHIFTNLILVFIMLSSVSLAAEDPIRSHSFRNNILGYFDYAFTAIFTVEILLKMTAFGAFLHKGSFCRNYFNLLDLLVVGVSLVSFGIQSSAISVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIMIVTTLLQFMFACIGVQLFKGKFYKCTDEAKQNPEECRGIYIVYKDGDVDNPMVKERVWQNSDFNFDNVLSAMMALFTVSTFEGWPALLYKAIDSNGENVGPVYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLRRYIPKNPYQYKFWYVVNSTGFEYIMFVLIMLNTLCLAMQHYGQSKLFNDAMDIMNMVFTGVFTVEMVLKLIAFKPKGYFSDAWNTFDSLIVIGSIVDVVLSEADHYFTDAWNTFDALIVVGSVVDIAITEVNPKPTETVTTDESGNSEDSARISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIAMLFFIYAVIGMQVFGKVAMRDNNQINRNNNFQTFPQAVLLLFRCATGEAWQEIMLACLPGKRCDPESDYNPGEEYTCGSNFAIIYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWSEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVAMNMPLNSDGTVMFNATLFALVRTALKIKTEGNLEQANEELRAVIKKIWKKTSMKLLDQVVPPAGDDEVTVGKFYATFLIQDYFRKFKKRKEQGLVGKYPAKNTTIALQAGLRTLHDIGPEIRRAISCDLQDDEPEENNPDEEEEVYKRNGALFGNHINHISSDRRDSFQQINTTHRPLHVQRPSIPSASDTEKNIYPHTGNSVYHNHHNHNSVGKQVPNSTNANLNNANVSKVVHGKHANFGSHEHRSENGYHSYSRADHEKRRRPSSRRTRYYETYIRSDSGDGRRPTICREERDIRDYCNDDHYLGEQEYYSGEEYYEEDSMLSGNRHVYDYHCRHHCHDSDFERPKGYHHPHGFFEEDDSQTCYDTKRSPRRRLLPPTPASNRRSSFNFECLRRQSSQDDIPLSPNFHHRTALPLHLMQQQVMAVAGLDSSKAHKHSPSRSTRSWATPPATPPNRDHTPYYTPLIQVDRAESTEHMNGSLPSLHRSSWYTDDPDISYRTFTPANLTVPNDFRHKHSDKQRSADSLVEAVLISEGLGRYAKDPKFVSATKHEIADACDMTIDEMESAASNLLNGNISNGTNGDMFPILSRQDYELQDFGPGYSDEEPEPGRYEEDLADEMICITSL", "length": 2182, "header": "tr|A0A8V1ADG1-1|CAC1D_CHICK Computationally mapped isoform of Voltage-dependent L-type calcium channel subunit alpha-1D OS=Gallus gallus OX=9031 GN=CACNA1D PE=1 SV=1 CANONICAL=O73700-1" }, "locus": { "chromosome": "12", "start_pos": 7395709, "end_pos": 7232067, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067508.1", "url": "https://www.ensembl.org/id/ENSGALT00010067508.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041251.1", "url": "https://www.ensembl.org/id/ENSGALP00010041251.1" } ] } }, { "isoform_ac": "A0A8V1AHW6-1", "url": "https://www.uniprot.org/uniprotkb/O73700/entry#A0A8V1AHW6-1", "sequence": { "sequence": "MQHHQQQQPEQHPEEANYASSTRIPLPGDGPTTQSNSSAPSKQTVLSWQAAIDAARQAKAAQNMNTTTAQPVGSLSQRKRQQYAKSKKQGNTSNSRPPRALFCLSLNNPIRRACISLVEWKPFDIFILLSIFANCVALAVYIPFPEDDSNSTNHNLEKVEYAFLIIFTVETFLKIIAYGLLLHPNAYVRNGWNLLDFVIVVVGLFSVILEQLTKETEGGSHSGGKPGGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFIGKMHKSCFLIDSDILVEEDPAPCAFSGNGRQCVMNGTECKGGWVGPNGGITNFDNFAFAMLTVFQCITMEGWTDVLYWMNDAMGFELPWVYFVSLVIFGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENDEEADEEGKRNTSMPTSETESVNTENVSGEGENPACCGSLCQTISKSKFSRRWRRWNRFNRRKCRAAVKSVTFYWLVIVLVFLNTLTISSEHYNQPDWLTQIQDIANKVLLALFTCEMLVKMYSLGLQAYFVSLFNRFDCFVVCGGIVETILVELEIMSPLGISVFRCVRLLRIFKVTRHWASLSNLVASLLNSMKSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDETQTKRSTFDNFPQALLTVFQILTGEDWNAVMYDGIMAYGGPSSSGMIVCIYFIILFICGNYILLNVFLAIAVDNLADAESLNTAQKEEAEEKERKKNARKESLENKKSEKSEGDQKKPKDSKVTIAEYGEGEDEDKDPYPPCDVPVGEDEEDEEDEPEVPAGPRPRRISELNMKEKITPIPEGSAFFIFSSTNPIRVGCHRLINHHIFTNLILVFIMLSSVSLAAEDPIRSHSFRNNILGYFDYAFTAIFTVEILLKMTAFGAFLHKGSFCRNYFNLLDLLVVGVSLVSFGIQSSAISVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIMIVTTLLQFMFACIGVQLFKGKFYKCTDEAKQNPEECRGIYIVYKDGDVDNPMVKERVWQNSDFNFDNVLSAMMALFTVSTFEGWPALLYKAIDSNGENVGPVYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLRRYIPKNPYQYKFWYVVNSTGFEYIMFVLIMLNTLCLAMQHYGQSKLFNDAMDIMNMVFTGVFTVEMVLKLIAFKPKGYFSDAWNTFDSLIVIGSIVDVVLSEADNSEDSARISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIAMLFFIYAVIGMQVFGKVAMRDNNQINRNNNFQTFPQAVLLLFRCATGEAWQEIMLACLPGKRCDPESDYNPGEEYTCGSNFAIIYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWSEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVAMNMPLNSDGTVMFNATLFALVRTALKIKTEGNLEQANEELRAVIKKIWKKTSMKLLDQVVPPAGDDEVTVGKFYATFLIQDYFRKFKKRKEQGLVGKYPAKNTTIALQAGLRTLHDIGPEIRRAISCDLQDDEPEENNPDEEEEVYKRNGALFGNHINHISSDRRDSFQQINTTHRPLHVQRPSIPSASDTEKNIYPHTGNSVYHNHHNHNSVGKQVPNSTNANLNNANVSKVVHGKHANFGSHEHRSENGYHSYSRADHEKRRRPSSRRTRYYETYIRSDSGDGRRPTICREERDIRDYCNDDHYLGEQEYYSGEEYYEEDSMLSGNRHVYDYHCRHHCHDSDFERPKGYHHPHGFFEEDDSQTCYDTKRSPRRRLLPPTPASNRRSSFNFECLRRQSSQDDIPLSPNFHHRTALPLHLMQQQVMAVAGLDSSKAHKHSPSRSTRSWATPPATPPNRDHTPYYTPLIQVDRAESTEHMNGSLPSLHRSSWYTDDPDISYRTFTPANLTVPNDFRHKHSDKQRSADSLVEAVLISEGLGRYAKDPKFVSATKHEIADACDMTIDEMESAASNLLNGNISNGTNGDMFPILSRQDYELQDFGPGYSDEEPEPGRYEEDLADEMICITSL", "length": 2141, "header": "tr|A0A8V1AHW6-1|CAC1D_CHICK Computationally mapped isoform of Voltage-dependent L-type calcium channel subunit alpha-1D OS=Gallus gallus OX=9031 GN=CACNA1D PE=1 SV=1 CANONICAL=O73700-1" }, "locus": { "chromosome": "12", "start_pos": 7395709, "end_pos": 7232067, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067510.1", "url": "https://www.ensembl.org/id/ENSGALT00010067510.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041253.1", "url": "https://www.ensembl.org/id/ENSGALP00010041253.1" } ] } }, { "isoform_ac": "O73700-1", "url": "https://www.uniprot.org/uniprotkb/O73700/entry#O73700-1", "sequence": { "sequence": "MQHHQQQQPEQHPEEANYASSTRIPLPGDGPTTQSNSSAPSKQTVLSWQAAIDAARQAKAAQNMNTTTAQPVGSLSQRKRQQYAKSKKQGNTSNSRPPRALFCLSLNNPIRRACISLVEWKPFDIFILLSIFANCVALAVYIPFPEDDSNSTNHNLEKVEYAFLIIFTVETFLKIIAYGLLLHPNAYVRNGWNLLDFVIVVVGLFSVILEQLTKETEGGSHSGGKPGGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFIGKMHKSCFLIDSDILVEEDPAPCAFSGNGRQCVMNGTECKGGWVGPNGGITNFDNFAFAMLTVFQCITMEGWTDVLYWVNDAIGCEWPWIYFVSLIILGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENDEEADEEGKRNRVTLADLMEEKKKSRLSCFGRSSNKHASMPTSETESVNTENVSGEGENPACCGSLCQTISKSKFSRRWRRWNRFNRRKCRAAVKSVTFYWLVIVLVFLNTLTISSEHYNQPDWLTQIQDIANKVLLALFTCEMLVKMYSLGLQAYFVSLFNRFDCFVVCGGIVETILVELEIMSPLGISVFRCVRLLRIFKVTRHWASLSNLVASLLNSMKSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDETQTKRSTFDNFPQALLTVFQILTGEDWNAVMYDGIMAYGGPSSSGMIVCIYFIILFICGNYILLNVFLAIAVDNLADAESLNTAQKEEAEEKERKKNARKESLENKKSEKSEGDQKKPKDSKVTIAEYGEGEDEDKDPYPPCDVPVGEDEEDEEDEPEVPAGPRPRRISELNMKEKITPIPEGSAFFIFSSTNPIRVGCHRLINHHIFTNLILVFIMLSSVSLAAEDPIRSHSFRNNILGYADYVFTSMFTFEIILKMTAFGAFLHKGSFCRNYFNLLDLLVVGVSLVSFGIQSSAISVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIMIVTTLLQFMFACIGVQLFKGKFYKCTDEAKQNPEECRGIYIVYKDGDVDNPMVKERVWQNSDFNFDNVLSAMMALFTVSTFEGWPALLYKAIDSNGENVGPVYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLRRYIPKNPYQYKFWYVVNSTGFEYIMFVLIMLNTLCLAMQHYGQSKLFNDAMDIMNMVFTGVFTVEMVLKLIAFKPKIFVRKKERWLGYFSDAWNTFDSLIVIGSIVDVVLSEADPKPTETVTTDESGNSEDSARISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIAMLFFIYAVIGMQVFGKVAMRDNNQINRNNNFQTFPQAVLLLFRCATGEAWQEIMLACLPGKRCDPESDYNPGEEYTCGSNFAIIYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWSEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVAMNMPLNSDGTVMFNATLFALVRTALKIKTEGNLEQANEELRAVIKKIWKKTSMKLLDQVVPPAGDDEVTVGKFYATFLIQDYFRKFKKRKEQGLVGKYPAKNTTIALQAGLRTLHDIGPEIRRAISCDLQDDEPEENNPDEEEEVYKRNGALFGNHINHISSDRRDSFQQINTTHRPLHVQRPSIPSASDTEKNIYPHTGNSVYHNHHNHNSVGKQVPNSTNANLNNANVSKVVHGKHANFGSHEHRSENGYHSYSRADHEKRRRPSSRRTRYYETYIRSDSGDGRRPTICREERDIRDYCNDDHYLGEQEYYSGEEYYEEDSMLSGNRHVYDYHCRHHCHDSDFERPKGYHHPHGFFEEDDSQTCYDTKRSPRRRLLPPTPASNRRSSFNFECLRRQSSQDDIPLSPNFHHRTALPLHLMQQQVMAVAGLDSSKAHKHSPSRSTRSWATPPATPPNRDHTPYYTPLIQVDRAESTEHMNGSLPSLHRSSWYTDDPDISYRTFTPANLTVPNDFRHKHSDKQRSADSLVEAVLISEGLGRYAKDPKFVSATKHEIADACDMTIDEMESAASNLLNGNISNGTNGDMFPILSRQDYELQDFGPGYSDEEPEPGRYEEDLADEMICITSL", "length": 2190, "header": "sp|O73700-1|CAC1D_CHICK Isoform 1 of Voltage-dependent L-type calcium channel subunit alpha-1D OS=Gallus gallus OX=9031 GN=CACNA1D PE=1 SV=1 CANONICAL=O73700-1" }, "locus": { "chromosome": "12", "start_pos": 7395709, "end_pos": 7232067, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067502.1", "url": "https://www.ensembl.org/id/ENSGALT00010067502.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041246.1", "url": "https://www.ensembl.org/id/ENSGALP00010041246.1" } ] } }, { "isoform_ac": "O73700-2", "url": "https://www.uniprot.org/uniprotkb/O73700/entry#O73700-2", "sequence": { "sequence": "MQHHQQQQPEQHPEEANYASSTRIPLPGDGPTTQSNSSAPSKQTVLSWQAAIDAARQAKAAQNMNTTTAQPVGSLSQRKRQQYAKSKKQGNTSNSRPPRALFCLSLNNPIRRACISLVEWKPFDIFILLSIFANCVALAVYIPFPEDDSNSTNHNLEKVEYAFLIIFTVETFLKIIAYGLLLHPNAYVRNGWNLLDFVIVVVGLFSVILEQLTKETEGGSHSGGKPGGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFIGKMHKSCFLIDSDILVEEDPAPCAFSGNGRQCVMNGTECKGGWVGPNGGITNFDNFAFAMLTVFQCITMEGWTDVLYWVNDAIGCEWPWIYFVSLIILGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENDEEADEEGKRNRVTLADLMEEKKKSRLSCFGRSSNKHASMPTSETESVNTENVSGEGENPACCGSLCQTISKSKFSRRWRRWNRFNRRKCRAAVKSVTFYWLVIVLVFLNTLTISSEHYNQPDWLTQIQDIANKVLLALFTCEMLVKMYSLGLQAYFVSLFNRFDCFVVCGGIVETILVELEIMSPLGISVFRCVRLLRIFKVTRHWASLSNLVASLLNSMKSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDETQTKRSTFDNFPQALLTVFQILTGEDWNAVMYDGIMAYGGPSSSGMIVCIYFIILFICGNYILLNVFLAIAVDNLADAESLNTAQKEEAEEKERKKNARKESLENKKSEKSEGDQKKPKDSKVTIAEYGEGEDEDKDPYPPCDVPVGEDEEDEEDEPEVPAGPRPRRISELNMKEKITPIPEGSAFFIFSSTNPIRVGCHRLINHHIFTNLILVFIMLSSVSLAAEDPIRSHSFRNNILGYFDYAFTAIFTVEILLKMTAFGAFLHKGSFCRNYFNLLDLLVVGVSLVSFGIQSSAISVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIMIVTTLLQFMFACIGVQLFKGKFYKCTDEAKQNPEECRGIYIVYKDGDVDNPMVKERVWQNSDFNFDNVLSAMMALFTVSTFEGWPALLYKAIDSNGENVGPVYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLRRYIPKNPYQYKFWYVVNSTGFEYIMFVLIMLNTLCLAMQHYGQSKLFNDAMDIMNMVFTGVFTVEMVLKLIAFKPKIFVRKKERWLGYFSDAWNTFDSLIVIGSIVDVVLSEADPKPTETVTTDESGNSEDSARISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIAMLFFIYAVIGMQVFGKVAMRDNNQINRNNNFQTFPQAVLLLFRCATGEAWQEIMLACLPGKRCDPESDYNPGEEYTCGSNFAIIYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWSEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVAMNMPLNSDGTVMFNATLFALVRTALKIKTEGNLEQANEELRAVIKKIWKKTSMKLLDQVVPPAGDDEVTVGKFYATFLIQDYFRKFKKRKEQGLVGKYPAKNTTIALQAGLRTLHDIGPEIRRAISCDLQDDEPEENNPDEEEEVYKRNGALFGNHINHISSDRRDSFQQINTTHRPLHVQRPSIPSASDTEKNIYPHTGNSVYHNHHNHNSVGKQVPNSTNANLNNANVSKVVHGKHANFGSHEHRSENGYHSYSRADHEKRRRPSSRRTRYYETYIRSDSGDGRRPTICREERDIRDYCNDDHYLGEQEYYSGEEYYEEDSMLSGNRHVYDYHCRHHCHDSDFERPKGYHHPHGFFEEDDSQTCYDTKRSPRRRLLPPTPASNRRSSFNFECLRRQSSQDDIPLSPNFHHRTALPLHLMQQQVMAVAGLDSSKAHKHSPSRSTRSWATPPATPPNRDHTPYYTPLIQVDRAESTEHMNGSLPSLHRSSWYTDDPDISYRTFTPANLTVPNDFRHKHSDKQRSADSLVEAVLISEGLGRYAKDPKFVSATKHEIADACDMTIDEMESAASNLLNGNISNGTNGDMFPILSRQDYELQDFGPGYSDEEPEPGRYEEDLADEMICITSL", "length": 2190, "header": "sp|O73700-2|CAC1D_CHICK Isoform 2 of Voltage-dependent L-type calcium channel subunit alpha-1D OS=Gallus gallus OX=9031 GN=CACNA1D PE=1 SV=1 CANONICAL=O73700-1" }, "locus": { "chromosome": "12", "start_pos": 7395709, "end_pos": 7232067, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067500.1", "url": "https://www.ensembl.org/id/ENSGALT00010067500.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041245.1", "url": "https://www.ensembl.org/id/ENSGALP00010041245.1" } ] } }, { "isoform_ac": "O73700-3", "url": "https://www.uniprot.org/uniprotkb/O73700/entry#O73700-3", "sequence": { "sequence": "MQHHQQQQPEQHPEEANYASSTRIPLPGDGPTTQSNSSAPSKQTVLSWQAAIDAARQAKAAQNMNTTTAQPVGSLSQRKRQQYAKSKKQGNTSNSRPPRALFCLSLNNPIRRACISLVEWKPFDIFILLSIFANCVALAVYIPFPEDDSNSTNHNLEKVEYAFLIIFTVETFLKIIAYGLLLHPNAYVRNGWNLLDFVIVVVGLFSVILEQLTKETEGGSHSGGKPGGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFIGKMHKSCFLIDSDILVEEDPAPCAFSGNGRQCVMNGTECKGGWVGPNGGITNFDNFAFAMLTVFQCITMEGWTDVLYWVNDAIGCEWPWIYFVSLIILGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENDEEADEEGKRNRVTLADLMEEKKKSRLSCFGRSSNKHASMPTSETESVNTENVSGEGENPACCGSLCQTISKSKFSRRWRRWNRFNRRKCRAAVKSVTFYWLVIVLVFLNTLTISSEHYNQPDWLTQIQDIANKVLLALFTCEMLVKMYSLGLQAYFVSLFNRFDCFVVCGGIVETILVELEIMSPLGISVFRCVRLLRIFKVTRHWASLSNLVASLLNSMKSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDETQTKRSTFDNFPQALLTVFQILTGEDWNAVMYDGIMAYGGPSSSGMIVCIYFIILFICGNYILLNVFLAIAVDNLADAESLNTAQKEEAEEKERKKNARKESLENKKSEKSEGDQKKPKDSKVTIAEYGEGEDEDKDPYPPCDVPVGEDEEDEEDEPEVPAGPRPRRISELNMKEKITPIPEGSAFFIFSSTNPIRVGCHRLINHHIFTNLILVFIMLSSVSLAAEDPIRSHSFRNNILGYADYVFTSMFTFEIILKMTAFGAFLHKGSFCRNYFNLLDLLVVGVSLVSFGIQSSAISVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIMIVTTLLQFMFACIGVQLFKGKFYKCTDEAKQNPEECRGIYIVYKDGDVDNPMVKERVWQNSDFNFDNVLSAMMALFTVSTFEGWPALLYKAIDSNGENVGPVYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLRRYIPKNPYQYKFWYVVNSTGFEYIMFVLIMLNTLCLAMQHYGQSKLFNDAMDIMNMVFTGVFTVEMVLKLIAFKPKIFVRKKERWLHYFTDAWNTFDALIVVGSVVDIAITEVNPKPTETVTTDESGNSEDSARISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIAMLFFIYAVIGMQVFGKVAMRDNNQINRNNNFQTFPQAVLLLFRCATGEAWQEIMLACLPGKRCDPESDYNPGEEYTCGSNFAIIYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWSEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVAMNMPLNSDGTVMFNATLFALVRTALKIKTEGNLEQANEELRAVIKKIWKKTSMKLLDQVVPPAGDDEVTVGKFYATFLIQDYFRKFKKRKEQGLVGKYPAKNTTIALQAGLRTLHDIGPEIRRAISCDLQDDEPEENNPDEEEEVYKRNGALFGNHINHISSDRRDSFQQINTTHRPLHVQRPSIPSASDTEKNIYPHTGNSVYHNHHNHNSVGKQVPNSTNANLNNANVSKVVHGKHANFGSHEHRSENGYHSYSRADHEKRRRPSSRRTRYYETYIRSDSGDGRRPTICREERDIRDYCNDDHYLGEQEYYSGEEYYEEDSMLSGNRHVYDYHCRHHCHDSDFERPKGYHHPHGFFEEDDSQTCYDTKRSPRRRLLPPTPASNRRSSFNFECLRRQSSQDDIPLSPNFHHRTALPLHLMQQQVMAVAGLDSSKAHKHSPSRSTRSWATPPATPPNRDHTPYYTPLIQVDRAESTEHMNGSLPSLHRSSWYTDDPDISYRTFTPANLTVPNDFRHKHSDKQRSADSLVEAVLISEGLGRYAKDPKFVSATKHEIADACDMTIDEMESAASNLLNGNISNGTNGDMFPILSRQDYELQDFGPGYSDEEPEPGRYEEDLADEMICITSL", "length": 2190, "header": "sp|O73700-3|CAC1D_CHICK Isoform 3 of Voltage-dependent L-type calcium channel subunit alpha-1D OS=Gallus gallus OX=9031 GN=CACNA1D PE=1 SV=1 CANONICAL=O73700-1" }, "locus": { "chromosome": "12", "start_pos": 7395709, "end_pos": 7232067, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067506.1", "url": "https://www.ensembl.org/id/ENSGALT00010067506.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041249.1", "url": "https://www.ensembl.org/id/ENSGALP00010041249.1" } ] } }, { "isoform_ac": "O73700-4", "url": "https://www.uniprot.org/uniprotkb/O73700/entry#O73700-4", "sequence": { "sequence": "MQHHQQQQPEQHPEEANYASSTRIPLPGDGPTTQSNSSAPSKQTVLSWQAAIDAARQAKAAQNMNTTTAQPVGSLSQRKRQQYAKSKKQGNTSNSRPPRALFCLSLNNPIRRACISLVEWKPFDIFILLSIFANCVALAVYIPFPEDDSNSTNHNLEKVEYAFLIIFTVETFLKIIAYGLLLHPNAYVRNGWNLLDFVIVVVGLFSVILEQLTKETEGGSHSGGKPGGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFIGKMHKSCFLIDSDILVEEDPAPCAFSGNGRQCVMNGTECKGGWVGPNGGITNFDNFAFAMLTVFQCITMEGWTDVLYWVNDAIGCEWPWIYFVSLIILGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENDEEADEEGKRNRVTLADLMEEKKKSRLSCFGRSSNKHASMPTSETESVNTENVSGEGENPACCGSLCQTISKSKFSRRWRRWNRFNRRKCRAAVKSVTFYWLVIVLVFLNTLTISSEHYNQPDWLTQIQDIANKVLLALFTCEMLVKMYSLGLQAYFVSLFNRFDCFVVCGGIVETILVELEIMSPLGISVFRCVRLLRIFKVTRHWASLSNLVASLLNSMKSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDETQTKRSTFDNFPQALLTVFQILTGEDWNAVMYDGIMAYGGPSSSGMIVCIYFIILFICGNYILLNVFLAIAVDNLADAESLNTAQKEEAEEKERKKNARKESLENKKSEKSEGDQKKPKDSKVTIAEYGEGEDEDKDPYPPCDVPVGEDEEDEEDEPEVPAGPRPRRISELNMKEKITPIPEGSAFFIFSSTNPIRVGCHRLINHHIFTNLILVFIMLSSVSLAAEDPIRSHSFRNNILGYADYVFTSMFTFEIILKMTAFGAFLHKGSFCRNYFNLLDLLVVGVSLVSFGIQSSAISVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIMIVTTLLQFMFACIGVQLFKGKFYKCTDEAKQNPEECRGIYIVYKDGDVDNPMVKERVWQNSDFNFDNVLSAMMALFTVSTFEGWPALLYKAIDSNGENVGPVYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLRRYIPKNPYQYKFWYVVNSTGFEYIMFVLIMLNTLCLAMQHYGQSKLFNDAMDIMNMVFTGVFTVEMVLKLIAFKPKGYFSDAWNTFDSLIVIGSIVDVVLSEADPKPTETVTTDESGNSEDSARISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIAMLFFIYAVIGMQVFGKVAMRDNNQINRNNNFQTFPQAVLLLFRCATGEAWQEIMLACLPGKRCDPESDYNPGEEYTCGSNFAIIYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWSEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVAMNMPLNSDGTVMFNATLFALVRTALKIKTEGNLEQANEELRAVIKKIWKKTSMKLLDQVVPPAGDDEVTVGKFYATFLIQDYFRKFKKRKEQGLVGKYPAKNTTIALQAGLRTLHDIGPEIRRAISCDLQDDEPEENNPDEEEEVYKRNGALFGNHINHISSDRRDSFQQINTTHRPLHVQRPSIPSASDTEKNIYPHTGNSVYHNHHNHNSVGKQVPNSTNANLNNANVSKVVHGKHANFGSHEHRSENGYHSYSRADHEKRRRPSSRRTRYYETYIRSDSGDGRRPTICREERDIRDYCNDDHYLGEQEYYSGEEYYEEDSMLSGNRHVYDYHCRHHCHDSDFERPKGYHHPHGFFEEDDSQTCYDTKRSPRRRLLPPTPASNRRSSFNFECLRRQSSQDDIPLSPNFHHRTALPLHLMQQQVMAVAGLDSSKAHKHSPSRSTRSWATPPATPPNRDHTPYYTPLIQVDRAESTEHMNGSLPSLHRSSWYTDDPDISYRTFTPANLTVPNDFRHKHSDKQRSADSLVEAVLISEGLGRYAKDPKFVSATKHEIADACDMTIDEMESAASNLLNGNISNGTNGDMFPILSRQDYELQDFGPGYSDEEPEPGRYEEDLADEMICITSL", "length": 2180, "header": "sp|O73700-4|CAC1D_CHICK Isoform 4 of Voltage-dependent L-type calcium channel subunit alpha-1D OS=Gallus gallus OX=9031 GN=CACNA1D PE=1 SV=1 CANONICAL=O73700-1" }, "locus": {} }, { "isoform_ac": "O73700-5", "url": "https://www.uniprot.org/uniprotkb/O73700/entry#O73700-5", "sequence": { "sequence": "MQHHQQQQPEQHPEEANYASSTRIPLPGDGPTTQSNSSAPSKQTVLSWQAAIDAARQAKAAQNMNTTTAQPVGSLSQRKRQQYAKSKKQGNTSNSRPPRALFCLSLNNPIRRACISLVEWKPFDIFILLSIFANCVALAVYIPFPEDDSNSTNHNLEKVEYAFLIIFTVETFLKIIAYGLLLHPNAYVRNGWNLLDFVIVVVGLFSVILEQLTKETEGGSHSGGKPGGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFIGKMHKSCFLIDSDILVEEDPAPCAFSGNGRQCVMNGTECKGGWVGPNGGITNFDNFAFAMLTVFQCITMEGWTDVLYWVNDAIGCEWPWIYFVSLIILGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENDEEADEEGKRNRVTLADLMEEKKKSRLSCFGRSSNKHASMPTSETESVNTENVSGEGENPACCGSLCQTISKSKFSRRWRRWNRFNRRKCRAAVKSVTFYWLVIVLVFLNTLTISSEHYNQPDWLTQIQDIANKVLLALFTCEMLVKMYSLGLQAYFVSLFNRFDCFVVCGGIVETILVELEIMSPLGISVFRCVRLLRIFKVTRHWASLSNLVASLLNSMKSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDETQTKRSTFDNFPQALLTVFQILTGEDWNAVMYDGIMAYGGPSSSGMIVCIYFIILFICGNYILLNVFLAIAVDNLADAESLNTAQKEEAEEKERKKNARKESLENKKSEKSEGDQKKPKDSKVTIAEYGEGEDEDKDPYPPCDVPVGEDEEDEEDEPEVPAGPRPRRISELNMKEKITPIPEGSAFFIFSSTNPIRVGCHRLINHHIFTNLILVFIMLSSVSLAAEDPIRSHSFRNNILGYADYVFTSMFTFEIILKMTAFGAFLHKGSFCRNYFNLLDLLVVGVSLVSFGIQSSAISVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIMIVTTLLQFMFACIGVQLFKGKFYKCTDEAKQNPEECRGIYIVYKDGDVDNPMVKERVWQNSDFNFDNVLSAMMALFTVSTFEGWPALLYKAIDSNGENVGPVYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLRRYIPKNPYQYKFWYVVNSTGFEYIMFVLIMLNTLCLAMQHYGQSKLFNDAMDIMNMVFTGVFTVEMVLKLIAFKPKIFVRKKERWLGYFSDAWNTFDSLIVIGSIVDVVLSEADPKPTETVTTDESGNSEDSARISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIAMLFFIYAVIGMQVFGKVAMRDNNQINRNNNFQTFPQAVLLLFRCATGEAWQEIMLACLPGKRCDPESDYNPGEEYTCGSNFAIIYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWSEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVAMNMPLNSDGTVMFNATLFALVRTALKIKTEGNLEQANEELRAVIKKIWKKTSMKLLDQVVPPAGDDEVTVGKFYATFLIQDYFRKFKKRKEQGLVGKYPAKNTTIALQVLIAHTAQTPFCSPASKLFPFGAEAWLQRAAGVA", "length": 1704, "header": "sp|O73700-5|CAC1D_CHICK Isoform 5 of Voltage-dependent L-type calcium channel subunit alpha-1D OS=Gallus gallus OX=9031 GN=CACNA1D PE=1 SV=1 CANONICAL=O73700-1" }, "locus": {} }, { "isoform_ac": "O73700-6", "url": "https://www.uniprot.org/uniprotkb/O73700/entry#O73700-6", "sequence": { "sequence": "MQHHQQQQPEQHPEEANYASSTRIPLPGDGPTTQSNSSAPSKQTVLSWQAAIDAARQAKAAQNMNTTTAQPVGSLSQRKRQQYAKSKKQGNTSNSRPPRALFCLSLNNPIRRACISLVEWKPFDIFILLSIFANCVALAVYIPFPEDDSNSTNHNLEKVEYAFLIIFTVETFLKIIAYGLLLHPNAYVRNGWNLLDFVIVVVGLFSVILEQLTKETEGGSHSGGKPGGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFIGKMHKSCFLIDSDILVEEDPAPCAFSGNGRQCVMNGTECKGGWVGPNGGITNFDNFAFAMLTVFQCITMEGWTDVLYWVNDAIGCEWPWIYFVSLIILGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENDEEADEEGKRNRVTLADLMEEKKKSRLSCFGRSSNKHASMPTSETESVNTENVSGEGENPACCGSLCQTISKSKFSRRWRRWNRFNRRKCRAAVKSVTFYWLVIVLVFLNTLTISSEHYNQPDWLTQIQDIANKVLLALFTCEMLVKMYSLGLQAYFVSLFNRFDCFVVCGGIVETILVELEIMSPLGISVFRCVRLLRIFKVTRHWASLSNLVASLLNSMKSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDETQTKRSTFDNFPQALLTVFQILTGEDWNAVMYDGIMAYGGPSSSGMIVCIYFIILFICGNYILLNVFLAIAVDNLADAESLNTAQKEEAEEKERKKNARKESLENKKSEKSEGDQKKPKDSKVTIAEYGEGEDEDKDPYPPCDVPVGEDEEDEEDEPEVPAGPRPRRISELNMKEKITPIPEGSAFFIFSSTNPIRVGCHRLINHHIFTNLILVFIMLSSVSLAAEDPIRSHSFRNNILGYADYVFTSMFTFEIILKMTAFGAFLHKGSFCRNYFNLLDLLVVGVSLVSFGIQSSAISVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIMIVTTLLQFMFACIGVQLFKGKFYKCTDEAKQNPEECRGIYIVYKDGDVDNPMVKERVWQNSDFNFDNVLSAMMALFTVSTFEGWPALLYKAIDSNGENVGPVYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLRRYIPKNPYQYKFWYVVNSTGFEYIMFVLIMLNTLCLAMQHYGQSKLFNDAMDIMNMVFTGVFTVEMVLKLIAFKPKIFVRKKERWLGYFSDAWNTFDSLIVIGSIVDVVLSEADPKPTETVTTDESGNSEDSARISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIAMLFFIYAVIGMQVFGKVAMRDNNQINRNNNFQTFPQAVLLLFRCATGEAWQEIMLACLPGKRCDPESDYNPGEEYTCGSNFAIIYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWSEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVAMNMPLNSDGTVMFNATLFALVRTALKIKTEGNLEQANEELRAVIKKIWKKTSMKLLDQVVPPAGDDEVTVGKFYATFLIQDYFRKFKKRKEQGLVGKYPAKNTTIALQAGLRTLHDIGPEIRRAISCDLQDDEPEENNPDEEEEVYKVMSEHGYVIFLLCNMSFIE", "length": 1728, "header": "sp|O73700-6|CAC1D_CHICK Isoform 6 of Voltage-dependent L-type calcium channel subunit alpha-1D OS=Gallus gallus OX=9031 GN=CACNA1D PE=1 SV=1 CANONICAL=O73700-1" }, "locus": {} }, { "isoform_ac": "O73700-7", "url": "https://www.uniprot.org/uniprotkb/O73700/entry#O73700-7", "sequence": { "sequence": "MQHHQQQQPEQHPEEANYASSTRIPLPGDGPTTQSNSSAPSKQTVLSWQAAIDAARQAKAAQNMNTTTAQPVGSLSQRKRQQYAKSKKQGNTSNSRPPRALFCLSLNNPIRRACISLVEWKPFDIFILLSIFANCVALAVYIPFPEDDSNSTNHNLEKVEYAFLIIFTVETFLKIIAYGLLLHPNAYVRNGWNLLDFVIVVVGLFSVILEQLTKETEGGSHSGGKPGGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFIGKMHKSCFLIDSDILVEEDPAPCAFSGNGRQCVMNGTECKGGWVGPNGGITNFDNFAFAMLTVFQCITMEGWTDVLYWVNDAIGCEWPWIYFVSLIILGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENDEEADEEGKRNRVTLADLMEEKKKSRLSCFGRSSNKHASMPTSETESVNTENVSGEGENPACCGSLCQTISKSKFSRRWRRWNRFNRRKCRAAVKSVTFYWLVIVLVFLNTLTISSEHYNQPDWLTQIQDIANKVLLALFTCEMLVKMYSLGLQAYFVSLFNRFDCFVVCGGIVETILVELEIMSPLGISVFRCVRLLRIFKVTRHWASLSNLVASLLNSMKSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDETQTKRSTFDNFPQALLTVFQILTGEDWNAVMYDGIMAYGGPSSSGMIVCIYFIILFICGNYILLNVFLAIAVDNLADAESLNTAQKEEAEEKERKKNARKESLENKKSEKSEGDQKKPKDSKVTIAEYGEGEDEDKDPYPPCDVPVGEDEEDEEDEPEVPAGPRPRRISELNMKEKITPIPEGSAFFIFSSTNPIRVGCHRLINHHIFTNLILVFIMLSSVSLAAEDPIRSHSFRNNILGYADYVFTSMFTFEIILKMTAFGAFLHKGSFCRNYFNLLDLLVVGVSLVSFGIQSSAISVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIMIVTTLLQFMFACIGVQLFKGKFYKCTDEAKQNPEECRGIYIVYKDGDVDNPMVKERVWQNSDFNFDNVLSAMMALFTVSTFEGWPALLYKAIDSNGENVGPVYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLRRYIPKNPYQYKFWYVVNSTGFEYIMFVLIMLNTLCLAMQHYGQSKLFNDAMDIMNMVFTGVFTVEMVLKLIAFKPKIFVRKKERWLGYFSDAWNTFDSLIVIGSIVDVVLSEADPKPTETVTTDESGNSEDSARISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIAMLFFIYAVIGMQVFGKVAMRDNNQINRNNNFQTFPQAVLLLFRCATGEAWQEIMLACLPGKRCDPESDYNPGEEYTCGSNFAIIYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWSEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVAMNMPLNSDGTVMFNATLFALVRTALKIKTEGNLEQANEELRAVIKKIWKKTSMKLLDQVVPPAGDDEVTVGKFYATFLIQDYFRKFKKRKEQGLVGKYPAKNTTIALQAGLRTLHDIGPEIRRAISCDLQDDEPEENNPDEEEEVYKRNGALFGNHINHISSDRRDSFQQINTTHRPLHVQRPSIPSASDTEKNIYPHTGNSVYHNHHNHNSVGKQVPNSTNANLNNANVSKVVHGKHANFGSHEHRSENGYHSYSRADHEKRRRPSSRRTRYYETYIRSDSGDGRRPTICREERDIRDYCNDDHYLGEQEYYSGEEYYEEDSMLSGNRNGP", "length": 1894, "header": "sp|O73700-7|CAC1D_CHICK Isoform 7 of Voltage-dependent L-type calcium channel subunit alpha-1D OS=Gallus gallus OX=9031 GN=CACNA1D PE=1 SV=1 CANONICAL=O73700-1" }, "locus": {} }, { "isoform_ac": "O73700-8", "url": "https://www.uniprot.org/uniprotkb/O73700/entry#O73700-8", "sequence": { "sequence": "MQHHQQQQPEQHPEEANYASSTRIPLPGDGPTTQSNSSAPSKQTVLSWQAAIDAARQAKAAQNMNTTTAQPVGSLSQRKRQQYAKSKKQGNTSNSRPPRALFCLSLNNPIRRACISLVEWKPFDIFILLSIFANCVALAVYIPFPEDDSNSTNHNLEKVEYAFLIIFTVETFLKIIAYGLLLHPNAYVRNGWNLLDFVIVVVGLFSVILEQLTKETEGGSHSGGKPGGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFIGKMHKSCFLIDSDILVEEDPAPCAFSGNGRQCVMNGTECKGGWVGPNGGITNFDNFAFAMLTVFQCITMEGWTDVLYWVNDAIGCEWPWIYFVSLIILGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENDEEADEEGKRNASMPTSETESVNTENVSGEGENPACCGSLCQTISKSKFSRRWRRWNRFNRRKCRAAVKSVTFYWLVIVLVFLNTLTISSEHYNQPDWLTQIQDIANKVLLALFTCEMLVKMYSLGLQAYFVSLFNRFDCFVVCGGIVETILVELEIMSPLGISVFRCVRLLRIFKVTRHWASLSNLVASLLNSMKSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDETQTKRSTFDNFPQALLTVFQILTGEDWNAVMYDGIMAYGGPSSSGMIVCIYFIILFICGNYILLNVFLAIAVDNLADAESLNTAQKEEAEEKERKKNARKESLENKKSEKSEGDQKKPKDSKVTIAEYGEGEDEDKDPYPPCDVPVGEDEEDEEDEPEVPAGPRPRRISELNMKEKITPIPEGSAFFIFSSTNPIRVGCHRLINHHIFTNLILVFIMLSSVSLAAEDPIRSHSFRNNILGYADYVFTSMFTFEIILKMTAFGAFLHKGSFCRNYFNLLDLLVVGVSLVSFGIQSSAISVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIMIVTTLLQFMFACIGVQLFKGKFYKCTDEAKQNPEECRGIYIVYKDGDVDNPMVKERVWQNSDFNFDNVLSAMMALFTVSTFEGWPALLYKAIDSNGENVGPVYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLRRYIPKNPYQYKFWYVVNSTGFEYIMFVLIMLNTLCLAMQHYGQSKLFNDAMDIMNMVFTGVFTVEMVLKLIAFKPKIFVRKKERWLGYFSDAWNTFDSLIVIGSIVDVVLSEADPKPTETVTTDESGNSEDSARISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIAMLFFIYAVIGMQVFGKVAMRDNNQINRNNNFQTFPQAVLLLFRCATGEAWQEIMLACLPGKRCDPESDYNPGEEYTCGSNFAIIYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWSEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVAMNMPLNSDGTVMFNATLFALVRTALKIKTEGNLEQANEELRAVIKKIWKKTSMKLLDQVVPPAGDDEVTVGKFYATFLIQDYFRKFKKRKEQGLVGKYPAKNTTIALQAGLRTLHDIGPEIRRAISCDLQDDEPEENNPDEEEEVYKRNGALFGNHINHISSDRRDSFQQINTTHRPLHVQRPSIPSASDTEKNIYPHTGNSVYHNHHNHNSVGKQVPNSTNANLNNANVSKVVHGKHANFGSHEHRSENGYHSYSRADHEKRRRPSSRRTRYYETYIRSDSGDGRRPTICREERDIRDYCNDDHYLGEQEYYSGEEYYEEDSMLSGNRHVYDYHCRHHCHDSDFERPKGYHHPHGFFEEDDSQTCYDTKRSPRRRLLPPTPASNRRSSFNFECLRRQSSQDDIPLSPNFHHRTALPLHLMQQQVMAVAGLDSSKAHKHSPSRSTRSWATPPATPPNRDHTPYYTPLIQVDRAESTEHMNGSLPSLHRSSWYTDDPDISYRTFTPANLTVPNDFRHKHSDKQRSADSLVEAVLISEGLGRYAKDPKFVSATKHEIADACDMTIDEMESAASNLLNGNISNGTNGDMFPILSRQDYELQDFGPGYSDEEPEPGRYEEDLADEMICITSL", "length": 2164, "header": "sp|O73700-8|CAC1D_CHICK Isoform 8 of Voltage-dependent L-type calcium channel subunit alpha-1D OS=Gallus gallus OX=9031 GN=CACNA1D PE=1 SV=1 CANONICAL=O73700-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 150, "start_aa": "Asn", "end_pos": 150, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn150", "evidence": [ { "id": "O73700", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O73700#ptm_processing" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1943, "start_aa": "Thr", "end_pos": 1943, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1943", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2016, "start_aa": "Thr", "end_pos": 2016, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2016", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 324, "start_aa": "Asn", "end_pos": 324, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn324", "evidence": [ { "id": "A0A8V1A5S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5S5#ptm_processing" }, { "id": "PIRSR602077-3", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR602077-3" }, { "id": "A0A8V1AHW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHW6#ptm_processing" }, { "id": "A0A8V1AAN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAN9#ptm_processing" }, { "id": "A0A8V1AAP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAP3#ptm_processing" }, { "id": "A0A8V1ADG1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADG1#ptm_processing" }, { "id": "O73700", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O73700#ptm_processing" }, { "id": "A0A1D5PY30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PY30#ptm_processing" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "RIM binding proteins (RBPs) couple Rab3-interacting molecules (RIMs) to voltage-gated Ca(2+) channels.", "journal": "Neuron", "date": "2002", "authors": "Hibino H, Pironkova R, Onwumere O, Vologodskaia M, Hudspeth A J, Lesage F", "evidence": [ { "database": "UniProtKB", "id": "O73700", "url": "https://www.uniprot.org/uniprotkb/O73700" } ], "reference": [ { "type": "PubMed", "id": "11988172", "url": "https://glygen.org/publication/PubMed/11988172" } ] }, { "title": "Development and regeneration of hair cells share common functional features.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2007-11-27", "authors": "Levic Snezana, Nie Liping, Tuteja Dipika, Harvey Margaret, Sokolowski Bernd H A, Yamoah Ebenezer N", "evidence": [ { "database": "RefSeq", "id": "NP_990365", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990365" } ], "reference": [ { "type": "PubMed", "id": "18025474", "url": "https://glygen.org/publication/PubMed/18025474" } ] }, { "title": "Predominance of the alpha1D subunit in L-type voltage-gated Ca2+ channels of hair cells in the chicken's cochlea.", "journal": "Proc. Natl. Acad. Sci. U.S.A.", "date": "1997", "authors": "Kollmar R, Montgomery L G, Fak J, Henry L J, Hudspeth A J", "evidence": [ { "database": "UniProtKB", "id": "O73700", "url": "https://www.uniprot.org/uniprotkb/O73700" } ], "reference": [ { "type": "PubMed", "id": "9405708", "url": "https://glygen.org/publication/PubMed/9405708" } ] }, { "title": "Hair cell-specific splicing of mRNA for the alpha1D subunit of voltage-gated Ca2+ channels in the chicken's cochlea.", "journal": "Proc. Natl. Acad. Sci. 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"length": 1136, "header": "tr|A0A1D5PZB7-1|A0A1D5PZB7_CHICK Isoform 1 of Nitric oxide synthase OS=Gallus gallus OX=9031 GN=NOS2 PE=3 SV=1 CANONICAL=A0A1D5PZB7-1" }, "locus": { "chromosome": "19", "start_pos": 9696886, "end_pos": 9680066, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071433.1", "url": "https://www.ensembl.org/id/ENSGALT00010071433.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044123.1", "url": "https://www.ensembl.org/id/ENSGALP00010044123.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:395807", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395807", "resource": "KEGG Pathway" }, { "id": "R-GGA-1222556", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1222556", "resource": "Reactome", "description": "ROS and RNS production in phagocytes" }, { "id": "R-GGA-392154", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-392154", "resource": "Reactome", "description": "Nitric oxide stimulates guanylate cyclase" }, { "id": "R-GGA-9033241", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9033241", "resource": "Reactome", "description": "Peroxisomal protein import" } ], "orthologs": [ { "uniprot_canonical_ac": "F1MYR5-1", "protein_name": "Nitric oxide synthase", "gene_name": "NOS2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MACPWQFLFKIKSQKVDLATELDINNNVGKFYQPPSSPVTQDDPKRHSPGKHGNESPQPLTGTVKTSPESLSKLDAPPSACPRHVRIKNWGSGVTFQDTLHQKAKGDLSCKSKSCLASIMNPKSLTIGPRDKPTPPDELLPQAIEFVNQYYGSFKEAKIEEHLARVEAVTKEIETTGTYQLTGDELIFATKQAWRNAPRCIGRIQWSNLQVFDARSCSTAQEMFEHICRHVRYATNNGNIRSAITVFPQRSDGKHDFRVWNAQLIRYAGYQMPDGSIRGDPANVEFTQLCIDLGWKPKYGRFDVLPLVLQADGRDPELFEIPPDLVLEVPMEHPRYEWFRELELKWYALPAVANMLLEVGGLEFPGCPFNGWYMGTEVGVRDFCDAQRYNILEEVGRRMGLETHKVASLWKDRAVVEINVAVLHSFQKQNVTIMDHHSAAESFMKYMQNEYRSRGGCPADWIWLVPPISGSITPVFHQEMLNYVLSPFYYYQVEPWKTHVWQDERRRPQRREIRFKVLVKAVFFASVLMHKTMASRVRATILFATETGRSETLAQDLGALFSCAFNPKVLCMDQYQLSHLEEEQLLLVVTSTFGNGDSPGNGEKLKKSLLMLKELTNTFRYAVFGLGSSMYPQFCAFAHDIDQKLSQLGASQLVPTGEGDELSGQEEAFRSWAVQTFKAACETFDVSGKHHIEIPKLYTSNVTWDPQHYRLVQDSEPLDLNKALSSMHAKHVFTMRLKSQQNLQSPKSSRTTLLVELSCEGSQAPSYLPGEHLGVFPCNQPALVQGILERVVDGPAPHQPVRLETLCENGSYWVKDKRLPPCSLSQALTYFLDITTPPTQLLLRKLAQLATEEAEKQRLETLCQPSDYNKWKFTNSPTFLEVLEEFPSLRVSASFLLSQLPILKPRYYSISSSRDLTPTEIHLTVAVLTYRTRDGQGPLHHGVCSTWLSSLKPQDPVPCFVRSASGFQLPEDRSRPCILIGPGTGIAPFRSFWQQRLHEAEHKGLQGGRMTLVFGCRRPEEDHLYWEEMLEMARKGVLHEVHTAYSRLPDQPKVYVQDILRQRLAGEVLRVLHEEQGHLYVCGDVRMARDVARTLKQLMATALSLNEEQVEDYFFQLKNQKRYHEDIFGAVFPYEVKKDGAAGLPSNPRAPGAHRS", "length": 1156 }, "evidence": [ { "id": "A0A1D5PZB7", "url": "https://omabrowser.org/oma/group/A0A1D5PZB7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P29477-1", "protein_name": "Nitric oxide synthase, inducible", "gene_name": "Nos2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MACPWKFLFKVKSYQSDLKEEKDINNNVKKTPCAVLSPTIQDDPKSHQNGSPQLLTGTAQNVPESLDKLHVTSTRPQYVRIKNWGSGEILHDTLHHKATSDFTCKSKSCLGSIMNPKSLTRGPRDKPTPLEELLPHAIEFINQYYGSFKEAKIEEHLARLEAVTKEIETTGTYQLTLDELIFATKMAWRNAPRCIGRIQWSNLQVFDARNCSTAQEMFQHICRHILYATNNGNIRSAITVFPQRSDGKHDFRLWNSQLIRYAGYQMPDGTIRGDAATLEFTQLCIDLGWKPRYGRFDVLPLVLQADGQDPEVFEIPPDLVLEVTMEHPKYEWFQELGLKWYALPAVANMLLEVGGLEFPACPFNGWYMGTEIGVRDFCDTQRYNILEEVGRRMGLETHTLASLWKDRAVTEINVAVLHSFQKQNVTIMDHHTASESFMKHMQNEYRARGGCPADWIWLVPPVSGSITPVFHQEMLNYVLSPFYYYQIEPWKTHIWQNEKLRPRRREIRFRVLVKVVFFASMLMRKVMASRVRATVLFATETGKSEALARDLATLFSYAFNTKVVCMDQYKASTLEEEQLLLVVTSTFGNGDCPSNGQTLKKSLFMLRELNHTFRYAVFGLGSSMYPQFCAFAHDIDQKLSHLGASQLAPTGEGDELSGQEDAFRSWAVQTFRAACETFDVRSKHHIQIPKRFTSNATWEPQQYRLIQSPEPLDLNRALSSIHAKNVFTMRLKSQQNLQSEKSSRTTLLVQLTFEGSRGPSYLPGEHLGIFPGNQTALVQGILERVVDCPTPHQTVCLEVLDESGSYWVKDKRLPPCSLSQALTYFLDITTPPTQLQLHKLARFATDETDRQRLEALCQPSEYNDWKFSNNPTFLEVLEEFPSLHVPAAFLLSQLPILKPRYYSISSSQDHTPSEVHLTVAVVTYRTRDGQGPLHHGVCSTWIRNLKPQDPVPCFVRSVSGFQLPEDPSQPCILIGPGTGIAPFRSFWQQRLHDSQHKGLKGGRMSLVFGCRHPEEDHLYQEEMQEMVRKRVLFQVHTGYSRLPGKPKVYVQDILQKQLANEVLSVLHGEQGHLYICGDVRMARDVATTLKKLVATKLNLSEEQVEDYFFQLKSQKRYHEDIFGAVFSYGAKKGSALEEPKATRL", "length": 1144 }, "evidence": [ { "id": "A0A1D5PZB7", "url": "https://omabrowser.org/oma/group/A0A1D5PZB7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P35228-1", "protein_name": "Nitric oxide synthase, inducible", "gene_name": "NOS2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MACPWKFLFKTKFHQYAMNGEKDINNNVEKAPCATSSPVTQDDLQYHNLSKQQNESPQPLVETGKKSPESLVKLDATPLSSPRHVRIKNWGSGMTFQDTLHHKAKGILTCRSKSCLGSIMTPKSLTRGPRDKPTPPDELLPQAIEFVNQYYGSFKEAKIEEHLARVEAVTKEIETTGTYQLTGDELIFATKQAWRNAPRCIGRIQWSNLQVFDARSCSTAREMFEHICRHVRYSTNNGNIRSAITVFPQRSDGKHDFRVWNAQLIRYAGYQMPDGSIRGDPANVEFTQLCIDLGWKPKYGRFDVVPLVLQANGRDPELFEIPPDLVLEVAMEHPKYEWFRELELKWYALPAVANMLLEVGGLEFPGCPFNGWYMGTEIGVRDFCDVQRYNILEEVGRRMGLETHKLASLWKDQAVVEINIAVLHSFQKQNVTIMDHHSAAESFMKYMQNEYRSRGGCPADWIWLVPPMSGSITPVFHQEMLNYVLSPFYYYQVEAWKTHVWQDEKRRPKRREIPLKVLVKAVLFACMLMRKTMASRVRVTILFATETGKSEALAWDLGALFSCAFNPKVVCMDKYRLSCLEEERLLLVVTSTFGNGDCPGNGEKLKKSLFMLKELNNKFRYAVFGLGSSMYPRFCAFAHDIDQKLSHLGASQLTPMGEGDELSGQEDAFRSWAVQTFKAACETFDVRGKQHIQIPKLYTSNVTWDPHHYRLVQDSQPLDLSKALSSMHAKNVFTMRLKSRQNLQSPTSSRATILVELSCEDGQGLNYLPGEHLGVCPGNQPALVQGILERVVDGPTPHQTVRLEALDESGSYWVSDKRLPPCSLSQALTYFLDITTPPTQLLLQKLAQVATEEPERQRLEALCQPSEYSKWKFTNSPTFLEVLEEFPSLRVSAGFLLSQLPILKPRFYSISSSRDHTPTEIHLTVAVVTYHTRDGQGPLHHGVCSTWLNSLKPQDPVPCFVRNASGFHLPEDPSHPCILIGPGTGIAPFRSFWQQRLHDSQHKGVRGGRMTLVFGCRRPDEDHIYQEEMLEMAQKGVLHAVHTAYSRLPGKPKVYVQDILRQQLASEVLRVLHKEPGHLYVCGDVRMARDVAHTLKQLVAAKLKLNEEQVEDYFFQLKSQKRYHEDIFGAVFPYEAKKDRVAVQPSSLEMSAL", "length": 1153 }, "evidence": [ { "id": "A0A1D5PZB7", "url": "https://omabrowser.org/oma/group/A0A1D5PZB7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P79290-1", "protein_name": "Nitric oxide synthase, inducible", "gene_name": "NOS2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MACPWKFLFKAKSSRFDLTEEKDINNNLEKLRQASSSPVTQDDPKCPSRSRHRNECSQPLAETAKKSPDSLVKLDVLPPACPRHVRIKNWGSGMTFQDTLHREAKGDLACKSKSCLGAIMNPKSLTIGPRDKPTPPDELLPQAIEFVNLYYSSFKEAKIEEHLARVEAVTKEIETTGTYQLTGDELIFAAKQAWRNAPRCIGRIQWSNLQVFDARSCSTAQEMFEHICRHLRYATNNGNIRSAITVFPQRSDGKHDFRVWNAQLIRYAGYQMPDGTIIGDPASVEFTQLCIDLGWKPKYGRFDVVPLVLQADGRDPELFEIPPDLVLEVPMEHPKYEWFQELELKWYALPAVANMLLEVGGLEFPGCPFNGWYMGTEIGVRDFCDVQRYNILEEVGRRMGLETHKLASLWKDRAVVEINVAVLHSFQKQNVTIMDHHSAAESFMKYMQNEYRSRGGCPADWIWLVPPISGSITPVFHQEMLNYVLSPFYYYQVEAWKTHVWQDEKRRPRRKEIRFKVLVKAVLFAAVLMHKTMAARVRATILFATETGRSETLARDLGALFSCAFNPKVLCMDEYRLSRLEEEQLLLVVTSTFGNGGSPGNGEKLKKSLFMLKELTNKFRYAVFGLGSSMYPQFCAFAHDVDQKLSHLGASQLTPTGEGDELSGQEEAFRGWAVQTFKVACETFDVRGKHHIQIPKLYTSNVTWDPQLYRLVQDSEPLDLNKALSSMHAKYVFSMRLKSQQNLQSPQSSRTTLLVELCCEGSQGPSYLPGEHLGVFPANQPALVQGILERVVDGPAPHQPVRLETLSENGSYWVKDKRLPPCSLSQALTYFLDITTPPTQLLLRKLAQLATDEAERQRLETLCQPSDYNKWKFTNSPTFLEVLEEFPSLRVSASFLLSQLPILKPRYYSISSSRDRTPTEIHLTVAVLTYRTRDGQGPLHHGVCSTWLSSLKPQDLVPCFVRSASGFQLPEDPSRPCILIGPGTGIAPFRSFWQQRLHEAEHKGLQGGRMTLVFGCRRPDEDHLYQEEMLEMARKGVLHEVHTAYSRLPGQPKVYVQDLLRQRLAGEVLRVLHEEQGHLYVCGDVRMARDVACTLKQLVATALTLNEEQVEDYFFQLKSQKRYHEDIFGAVFPYEVKKEGAVGPPSDPRAPGAHGKS", "length": 1157 }, "evidence": [ { "id": "A0A1D5PZB7", "url": "https://omabrowser.org/oma/group/A0A1D5PZB7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q06518-1", "protein_name": "Nitric oxide synthase, inducible", "gene_name": "Nos2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MACPWKFLFRVKSYQGDLKEEKDINNNVEKTPGAIPSPTTQDDPKSHKHQNGFPQFLTGTAQNVPESLDKLHVTPSTRPQHVRIKNWGNGEIFHDTLHHKATSDISCKSKLCMGSIMNSKSLTRGPRDKPTPVEELLPQAIEFINQYYGSFKEAKIEEHLARLEAVTKEIETTGTYQLTLDELIFATKMAWRNAPRCIGRIQWSNLQVFDARSCSTASEMFQHICRHILYATNSGNIRSAITVFPQRSDGKHDFRIWNSQLIRYAGYQMPDGTIRGDPATLEFTQLCIDLGWKPRYGRFDVLPLVLQAHGQDPEVFEIPPDLVLEVTMEHPKYEWFQELGLKWYALPAVANMLLEVGGLEFPACPFNGWYMGTEIGVRDFCDTQRYNILEEVGRRMGLETHTLASLWKDRAVTEINAAVLHSFQKQNVTIMDHHTASESFMKHMQNEYRARGGCPADWIWLVPPVSGSITPVFHQEMLNYVLSPFYYYQIEPWKTHIWQDEKLRPRRREIRFTVLVKAVFFASVLMRKVMASRVRATVLFATETGKSEALARDLAALFSYAFNTKVVCMEQYKANTLEEEQLLLVVTSTFGNGDCPSNGQTLKKSLFMMKELGHTFRYAVFGLGSSMYPQFCAFAHDIDQKLSHLGASQLAPTGEGDELSGQEDAFRSWAVQTFRAACETFDVRSKHCIQIPKRYTSNATWEPEQYKLTQSPESLDLNKALSSIHAKNVFTMRLKSLQNLQSEKSSRTTLLVQLTFEGSRGPSYLPGEHLGIFPGNQTALVQGILERVVDCSSPDQTVCLEVLDESGSYWVKDKRLPPCSLRQALTYFLDITTPPTQLQLHKLARFATEETHRQRLEALCQPSEYNDWKFSNNPTFLEVLEEFPSLRVPAAFLLSQLPILKPRYYSISSSQDHTPSEVHLTVAVVTYRTRDGQGPLHHGVCSTWINNLKPEDPVPCFVRSVSGFQLPEDPSQPCILIGPGTGIAPFRSFWQQRLHDSQHRGLKGGRMTLVFGCRHPEEDHLYQEEMQEMVRKGVLFQVHTGYSRLPGKPKVYVQDILQKELADEVFSVLHGEQGHLYVCGDVRMARDVATTLKKLVAAKLNLSEEQVEDYFFQLKSQKRYHEDIFGAVFSYGAKKGNTLEEPKGTRL", "length": 1147 }, "evidence": [ { "id": "A0A1D5PZB7", "url": "https://omabrowser.org/oma/group/A0A1D5PZB7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 10, "go_terms": [ { "name": "nitric-oxide synthase activity", "id": "GO:0004517", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004517", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PZB7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZB7" } ], "pmid": "" }, { "name": "tetrahydrobiopterin binding", "id": "GO:0034617", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034617", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PZB7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZB7" } ], "pmid": "" }, { "name": "calmodulin binding", "id": "GO:0005516", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005516", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PZB7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZB7" } ], "pmid": "" }, { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PZB7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZB7" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PZB7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZB7" } ], "pmid": "" }, { "name": "flavin adenine dinucleotide binding", "id": "GO:0050660", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050660", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PZB7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZB7" } ], "pmid": "" }, { "name": "heme binding", "id": "GO:0020037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0020037", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PZB7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZB7" } ], "pmid": "" }, { "name": "arginine binding", "id": "GO:0034618", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034618", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PZB7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZB7" } ], "pmid": "" }, { "name": "FMN binding", "id": "GO:0010181", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010181", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PZB7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZB7" } ], "pmid": "" }, { "name": "NADP binding", "id": "GO:0050661", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050661", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PZB7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZB7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PZB7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZB7" } ], "pmid": "" }, { "name": "peroxisome", "id": "GO:0005777", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005777", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PZB7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZB7" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PZB7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZB7" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PZB7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZB7" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PZB7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZB7" } ], "pmid": "" }, { "name": "cortical cytoskeleton", "id": "GO:0030863", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030863", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PZB7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZB7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 17, "go_terms": [ { "name": "inflammatory response", "id": "GO:0006954", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006954", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PZB7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZB7" } ], "pmid": "" }, { "name": "negative regulation of gene expression", "id": "GO:0010629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010629", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PZB7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZB7" } ], "pmid": "" }, { "name": "response to lipopolysaccharide", "id": "GO:0032496", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032496", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PZB7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZB7" } ], "pmid": "" }, { "name": "positive regulation of interleukin-6 production", "id": "GO:0032755", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032755", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PZB7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZB7" } ], "pmid": "" }, { "name": "negative regulation of blood pressure", "id": "GO:0045776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045776", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PZB7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZB7" } ], "pmid": "" }, { "name": "regulation of insulin secretion", "id": "GO:0050796", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050796", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PZB7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZB7" } ], "pmid": "" }, { "name": "nitric oxide mediated signal transduction", "id": "GO:0007263", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007263", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PZB7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZB7" } ], "pmid": "" }, { "name": "circadian rhythm", "id": "GO:0007623", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007623", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PZB7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZB7" } ], "pmid": "" }, { "name": "Fc-gamma receptor signaling pathway involved in phagocytosis", "id": "GO:0038096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038096", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PZB7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZB7" } ], "pmid": "" }, { "name": "response to hormone", "id": "GO:0009725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009725", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PZB7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZB7" } ], "pmid": "" }, { "name": "defense response to bacterium", "id": "GO:0042742", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042742", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PZB7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZB7" } ], "pmid": "" }, { "name": "positive regulation of interleukin-8 production", "id": "GO:0032757", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032757", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PZB7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZB7" } ], "pmid": "" }, { "name": "negative regulation of protein catabolic process", "id": "GO:0042177", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042177", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PZB7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZB7" } ], "pmid": "" }, { "name": "nitric oxide biosynthetic process", "id": "GO:0006809", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006809", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PZB7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZB7" } ], "pmid": "" }, { "name": "L-arginine catabolic process", "id": "GO:0006527", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006527", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PZB7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZB7" } ], "pmid": "" }, { "name": "regulation of cytokine production involved in inflammatory response", "id": "GO:1900015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900015", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PZB7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZB7" } ], "pmid": "" }, { "name": "prostaglandin secretion", "id": "GO:0032310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032310", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PZB7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZB7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1101, "end_pos": 1103, "annotation": "n_glycosylation_sequon" }, { "start_pos": 16, "end_pos": 18, "annotation": "n_glycosylation_sequon" }, { "start_pos": 427, "end_pos": 429, "annotation": "n_glycosylation_sequon" }, { "start_pos": 573, "end_pos": 575, "annotation": "n_glycosylation_sequon" }, { "start_pos": 89, "end_pos": 91, "annotation": "n_glycosylation_sequon" }, { "start_pos": 951, "end_pos": 953, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "19897", "name": "", "equation": "2 L-arginine + 3 NADPH + 4 O2 + H(+) = 2 L-citrulline + 2 nitric oxide + 3 NADP(+) + 4 H2O", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0X354-1", "A0A8V1AAD1-1", "A0A1D5PZB7-1", "Q90703-1" ], "evidence": [ { "id": "19897", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/19897" } ] }, { "id": "R-GGA-418436", "name": "Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO)", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-ALL-29468" ], "output_participant_list": [ "R-ALL-202124" ], "enzyme_list": [ "A0A8V0X354-1", "A0A1D5PZB7-1" ], "evidence": [ { "id": "R-GGA-418436", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-418436" } ] }, { "id": "R-GGA-9033235", "name": "Cargo of PEX5S,L translocates from the cytosol to the peroxisomal matrix", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "peroxisomal membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XEK2-1", "A0A8V0XIT0-1", "A0A8V1ANC5-1", "E1BRR7-1", "F1N9G6-1", "A0A8V0YMJ0-1", "A0A1D5P3W4-1", "A0A1L1RJ90-1", "A0A8V0Y1Q3-1", "A0A8V0XXY0-1", "A0A8V0Y2T0-1", "A0A8V1AJL7-1", "F1NKY1-1", "A0A8V0ZLD0-1", "A0A8V0ZPK4-1", "A0A8V1A097-1", "A0A8V0YAP6-1", "A0A8V0ZIT7-1", "A0A8V0ZRI7-1", "A0A8V0ZVL2-1", "F1NG68-1", "A0A8V0ZC97-1", "A0A8V1A124-1", "A0A1D5PZB7-1", "A0A8V1A248-1", "A0A8V1A8Z1-1", "Q5ZL13-1", "A0A8V0ZI42-1", "A0A8V0ZQU7-1" ], "evidence": [ { "id": "R-GGA-9033235", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9033235" } ] }, { "id": "R-GGA-9033236", "name": "PEX5S,L:Cargo binds PEX13:PEX14:PEX2:PEX10:PEX12 (Docking and Translocation Module)", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "peroxisomal membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XEK2-1", "A0A8V0XIT0-1", "A0A8V1ANC5-1", "E1BRR7-1", "F1N9G6-1", "A0A8V0YMJ0-1", "A0A1D5P3W4-1", "A0A1L1RJ90-1", "A0A8V0Y1Q3-1", "A0A8V0XXY0-1", "A0A8V0Y2T0-1", "A0A8V1AJL7-1", "F1NKY1-1", "A0A8V0ZLD0-1", "A0A8V0ZPK4-1", "A0A8V1A097-1", "A0A8V0YAP6-1", "A0A8V0ZIT7-1", "A0A8V0ZRI7-1", "A0A8V0ZVL2-1", "F1NG68-1", "A0A8V0ZC97-1", "A0A8V1A124-1", "A0A1D5PZB7-1", "A0A8V1A248-1", "A0A8V1A8Z1-1", "Q5ZL13-1", "A0A8V0ZI42-1", "A0A8V0ZQU7-1" ], "evidence": [ { "id": "R-GGA-9033236", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9033236" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-202124", "participant_name": "NO [cytosol]", "crossref": [ { "id": "C00533", "database": "COMPOUND", "url": "" }, { "id": "HMDB0003378", "database": "HMDB Metabolite", "url": "" }, { "id": "2509", "database": "Guide to Pharmacology - Ligands", "url": "" }, { "id": "16480", "database": "ChEBI", "url": "" } ] }, { "participant_id": "R-ALL-29468", "participant_name": "L-Arg [cytosol]", "crossref": [ { "id": "32682", "database": "ChEBI", "url": "" }, { "id": "ZINC000001532525", "database": "ZINC", "url": "" }, { "id": "HMDB0062762", "database": "HMDB Metabolite", "url": "" }, { "id": "C00062", "database": "COMPOUND", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5P3W4", "gene_name": "SLC27A2", "activity": [ { "ec_number": "6.2.1.3", "activity": "a long-chain fatty acid + ATP + CoA = a long-chain fatty acyl-CoA + AMP + diphosphate.", "evidence": [ { "id": "A0A1D5P3W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P3W4" } ] }, { "ec_number": "6.2.1.3", "activity": "", "evidence": [ { "id": "A0A1D5P3W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P3W4" } ] } ] }, { "uniprot_ac": "A0A1D5PZB7", "gene_name": "NOS2", "activity": [ { "ec_number": "1.14.13.39", "activity": "2 L-arginine + 3 NADPH + 4 O2 + H(+) = 2 L-citrulline + 2 nitric oxide + 3 NADP(+) + 4 H2O.", "evidence": [ { "id": "A0A1D5PZB7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZB7" } ] }, { "ec_number": "1.14.13.39", "activity": "", "evidence": [ { "id": "A0A1D5PZB7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZB7" } ] } ] }, { "uniprot_ac": "A0A1L1RJ90", "gene_name": "HMGCL", "activity": [ { "ec_number": "4.1.3.4", "activity": "(3S)-3-hydroxy-3-methylglutaryl-CoA = acetoacetate + acetyl-CoA.", "evidence": [ { "id": "A0A1L1RJ90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RJ90" } ] }, { "ec_number": "4.1.3.4", "activity": "", "evidence": [ { "id": "A0A1L1RJ90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RJ90" } ] } ] }, { "uniprot_ac": "A0A8V0X354", "gene_name": "NOS1", "activity": [ { "ec_number": "1.14.13.39", "activity": "2 L-arginine + 3 NADPH + 4 O2 + H(+) = 2 L-citrulline + 2 nitric oxide + 3 NADP(+) + 4 H2O.", "evidence": [ { "id": "A0A8V0X354", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X354" } ] }, { "ec_number": "1.14.13.39", "activity": "", "evidence": [ { "id": "A0A8V0X354", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X354" } ] } ] }, { "uniprot_ac": "A0A8V0XEK2", "gene_name": "HACL1", "activity": [ { "ec_number": "4.1.2.63", "activity": "2-hydroxy-3-methylhexadecanoyl-CoA = 2-methylpentadecanal + formyl-CoA.", "evidence": [ { "id": "A0A8V0XEK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEK2" } ] }, { "ec_number": "4.1.2.63", "activity": "", "evidence": [ { "id": "A0A8V0XEK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEK2" } ] } ] }, { "uniprot_ac": "A0A8V0XIT0", "gene_name": "CROT", "activity": [ { "ec_number": "2.3.1.137", "activity": "octanoyl-CoA + (R)-carnitine = O-octanoyl-(R)-carnitine + CoA.", "evidence": [ { "id": "A0A8V0XIT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XIT0" } ] }, { "ec_number": "2.3.1.137", "activity": "", "evidence": [ { "id": "A0A8V0XIT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XIT0" } ] } ] }, { "uniprot_ac": "A0A8V0XXY0", "gene_name": "MLYCD", "activity": [ { "ec_number": "4.1.1.9", "activity": "malonyl-CoA + H(+) = acetyl-CoA + CO2.", "evidence": [ { "id": "A0A8V0XXY0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXY0" } ] }, { "ec_number": "4.1.1.9", "activity": "", "evidence": [ { "id": "A0A8V0XXY0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXY0" } ] } ] }, { "uniprot_ac": "A0A8V0Y1Q3", "gene_name": "NUDT7", "activity": [ { "ec_number": "3.6.1.77", "activity": "CoA + H2O = (R)-4'-phosphopantetheine + adenosine 3',5'-bisphosphate + 2 H(+).", "evidence": [ { "id": "A0A8V0Y1Q3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y1Q3" } ] }, { "ec_number": "3.6.1.77", "activity": "", "evidence": [ { "id": "A0A8V0Y1Q3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y1Q3" } ] } ] }, { "uniprot_ac": "A0A8V0Y2T0", "gene_name": "ECH1", "activity": [ { "ec_number": "5.3.3.21", "activity": "a (3E,5Z)-dienoyl-CoA = a (2E,4E)-(5,6-saturated)-dienoyl-CoA.", "evidence": [ { "id": "A0A8V0Y2T0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2T0" } ] }, { "ec_number": "5.3.3.21", "activity": "", "evidence": [ { "id": "A0A8V0Y2T0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2T0" } ] } ] }, { "uniprot_ac": "A0A8V0YAP6", "gene_name": "GNPAT", "activity": [ { "ec_number": "2.3.1.42", "activity": "dihydroxyacetone phosphate + an acyl-CoA = a 1-acylglycerone 3-phosphate + CoA.", "evidence": [ { "id": "A0A8V0YAP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAP6" } ] }, { "ec_number": "2.3.1.42", "activity": "", "evidence": [ { "id": "A0A8V0YAP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAP6" } ] } ] }, { "uniprot_ac": "A0A8V0YMJ0", "gene_name": "ACOT8", "activity": [ { "ec_number": "3.1.2.2", "activity": "hexadecanoyl-CoA + H2O = hexadecanoate + CoA + H(+).", "evidence": [ { "id": "A0A8V0YMJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ0" } ] }, { "ec_number": "3.1.2.27", "activity": "(3S)-3-hydroxy-3-methylglutaryl-CoA + H2O = 3-hydroxy-3-methylglutarate + CoA + H(+).", "evidence": [ { "id": "A0A8V0YMJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ0" } ] }, { "ec_number": "3.1.2.1", "activity": "acetyl-CoA + H2O = acetate + CoA + H(+).", "evidence": [ { "id": "A0A8V0YMJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ0" } ] }, { "ec_number": "3.1.2.11", "activity": "acetoacetyl-CoA + H2O = acetoacetate + CoA + H(+).", "evidence": [ { "id": "A0A8V0YMJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ0" } ] }, { "ec_number": "3.1.2.3", "activity": "succinyl-CoA + H2O = succinate + CoA + H(+).", "evidence": [ { "id": "A0A8V0YMJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ0" } ] }, { "ec_number": "3.1.2.5", "activity": "(3S)-3-hydroxy-3-methylglutaryl-CoA + H2O = 3-hydroxy-3-methylglutarate + CoA + H(+).", "evidence": [ { "id": "A0A8V0YMJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ0" } ] }, { "ec_number": "3.1.2.1", "activity": "", "evidence": [ { "id": "A0A8V0YMJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ0" } ] }, { "ec_number": "3.1.2.3", "activity": "", "evidence": [ { "id": "A0A8V0YMJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ0" } ] }, { "ec_number": "3.1.2.2", "activity": "", "evidence": [ { "id": "A0A8V0YMJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ0" } ] }, { "ec_number": "3.1.2.11", "activity": "", "evidence": [ { "id": "A0A8V0YMJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ0" } ] }, { "ec_number": "3.1.2.5", "activity": "", "evidence": [ { "id": "A0A8V0YMJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ0" } ] }, { "ec_number": "3.1.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YMJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ0" } ] } ] }, { "uniprot_ac": "A0A8V0ZC97", "gene_name": "PEX10", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZC97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC97" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZC97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC97" } ] } ] }, { "uniprot_ac": "A0A8V0ZI42", "gene_name": "IDE", "activity": [ { "ec_number": "3.4.24.56", "activity": "Degradation of insulin, glucagon and other polypeptides. No action on proteins.", "evidence": [ { "id": "A0A8V0ZI42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI42" } ] }, { "ec_number": "3.4.24.56", "activity": "", "evidence": [ { "id": "A0A8V0ZI42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI42" } ] } ] }, { "uniprot_ac": "A0A8V0ZIT7", "gene_name": "PECR", "activity": [ { "ec_number": "1.3.1.38", "activity": "a (2E)-enoyl-CoA + NADPH + H(+) = a 2,3-saturated acyl-CoA + NADP(+).", "evidence": [ { "id": "A0A8V0ZIT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIT7" } ] }, { "ec_number": "1.3.1.38", "activity": "", "evidence": [ { "id": "A0A8V0ZIT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIT7" } ] } ] }, { "uniprot_ac": "A0A8V0ZLD0", "gene_name": "TYSND1", "activity": [ { "ec_number": "3.4.21.-", "activity": "", "evidence": [ { "id": "A0A8V0ZLD0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLD0" } ] } ] }, { "uniprot_ac": "A0A8V0ZPK4", "gene_name": "IDH1", "activity": [ { "ec_number": "1.1.1.42", "activity": "D-threo-isocitrate + NADP(+) = 2-oxoglutarate + CO2 + NADPH.", "evidence": [ { "id": "A0A8V0ZPK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPK4" } ] }, { "ec_number": "1.1.1.42", "activity": "", "evidence": [ { "id": "A0A8V0ZPK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPK4" } ] } ] }, { "uniprot_ac": "A0A8V0ZQU7", "gene_name": "PAOX", "activity": [ { "ec_number": "1.5.3.13", "activity": "N(1)-acetylspermine + O2 + H2O = 3-acetamidopropanal + spermidine + H2O2.", "evidence": [ { "id": "A0A8V0ZQU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQU7" } ] }, { "ec_number": "1.5.3.13", "activity": "", "evidence": [ { "id": "A0A8V0ZQU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQU7" } ] } ] }, { "uniprot_ac": "A0A8V0ZRI7", "gene_name": "LONP2", "activity": [ { "ec_number": "3.4.21.-", "activity": "", "evidence": [ { "id": "A0A8V0ZRI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRI7" } ] } ] }, { "uniprot_ac": "A0A8V0ZVL2", "gene_name": "CAT", "activity": [ { "ec_number": "1.11.1.6", "activity": "2 H2O2 = O2 + 2 H2O.", "evidence": [ { "id": "A0A8V0ZVL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVL2" } ] }, { "ec_number": "1.11.1.6", "activity": "", "evidence": [ { "id": "A0A8V0ZVL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVL2" } ] } ] }, { "uniprot_ac": "A0A8V1A097", "gene_name": "HAO2", "activity": [ { "ec_number": "1.1.3.15", "activity": "glycolate + O2 = glyoxylate + H2O2.", "evidence": [ { "id": "A0A8V1A097", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A097" } ] }, { "ec_number": "1.1.3.15", "activity": "", "evidence": [ { "id": "A0A8V1A097", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A097" } ] } ] }, { "uniprot_ac": "A0A8V1A124", "gene_name": "AGXT", "activity": [ { "ec_number": "2.6.1.51", "activity": "L-serine + pyruvate = 3-hydroxypyruvate + L-alanine.", "evidence": [ { "id": "A0A8V1A124", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A124" } ] }, { "ec_number": "2.6.1.44", "activity": "2-oxobutanoate + L-alanine = (2S)-2-aminobutanoate + pyruvate.", "evidence": [ { "id": "A0A8V1A124", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A124" } ] }, { "ec_number": "2.6.1.44", "activity": "", "evidence": [ { "id": "A0A8V1A124", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A124" } ] }, { "ec_number": "2.6.1.51", "activity": "", "evidence": [ { "id": "A0A8V1A124", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A124" } ] } ] }, { "uniprot_ac": "A0A8V1A248", "gene_name": "EHHADH", "activity": [ { "ec_number": "1.1.1.35", "activity": "a (3S)-3-hydroxyacyl-CoA + NAD(+) = a 3-oxoacyl-CoA + NADH + H(+).", "evidence": [ { "id": "A0A8V1A248", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A248" } ] }, { "ec_number": "4.2.1.17", "activity": "(3S)-3-hydroxyadipyl-CoA = (E)-2,3-didehydroadipoyl-CoA + H2O.", "evidence": [ { "id": "A0A8V1A248", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A248" } ] }, { "ec_number": "5.3.3.8", "activity": "a (3Z)-enoyl-CoA = a 4-saturated (2E)-enoyl-CoA.", "evidence": [ { "id": "A0A8V1A248", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A248" } ] }, { "ec_number": "5.3.3.8", "activity": "", "evidence": [ { "id": "A0A8V1A248", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A248" } ] }, { "ec_number": "4.2.1.17", "activity": "", "evidence": [ { "id": "A0A8V1A248", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A248" } ] }, { "ec_number": "1.1.1.35", "activity": "", "evidence": [ { "id": "A0A8V1A248", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A248" } ] } ] }, { "uniprot_ac": "A0A8V1A8Z1", "gene_name": "SCP2", "activity": [ { "ec_number": "2.3.1.176", "activity": "4,8,12-trimethyltridecanoyl-CoA + propanoyl-CoA = 3-oxopristanoyl-CoA + CoA.", "evidence": [ { "id": "A0A8V1A8Z1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8Z1" } ] }, { "ec_number": "2.3.1.16", "activity": "an acyl-CoA + acetyl-CoA = a 3-oxoacyl-CoA + CoA.", "evidence": [ { "id": "A0A8V1A8Z1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8Z1" } ] }, { "ec_number": "2.3.1.155", "activity": "tetradecanoyl-CoA + acetyl-CoA = 3-oxohexadecanoyl-CoA + CoA.", "evidence": [ { "id": "A0A8V1A8Z1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8Z1" } ] }, { "ec_number": "2.3.1.16", "activity": "", "evidence": [ { "id": "A0A8V1A8Z1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8Z1" } ] }, { "ec_number": "2.3.1.155", "activity": "", "evidence": [ { "id": "A0A8V1A8Z1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8Z1" } ] }, { "ec_number": "2.3.1.176", "activity": "", "evidence": [ { "id": "A0A8V1A8Z1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8Z1" } ] } ] }, { "uniprot_ac": "A0A8V1AAD1", "gene_name": "NOS3", "activity": [ { "ec_number": "1.14.13.39", "activity": "2 L-arginine + 3 NADPH + 4 O2 + H(+) = 2 L-citrulline + 2 nitric oxide + 3 NADP(+) + 4 H2O.", "evidence": [ { "id": "A0A8V1AAD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAD1" } ] }, { "ec_number": "1.14.13.39", "activity": "", "evidence": [ { "id": "A0A8V1AAD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAD1" } ] } ] }, { "uniprot_ac": "A0A8V1AJL7", "gene_name": "CRAT", "activity": [ { "ec_number": "2.3.1.137", "activity": "octanoyl-CoA + (R)-carnitine = O-octanoyl-(R)-carnitine + CoA.", "evidence": [ { "id": "A0A8V1AJL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJL7" } ] }, { "ec_number": "2.3.1.7", "activity": "(R)-carnitine + acetyl-CoA = O-acetyl-(R)-carnitine + CoA.", "evidence": [ { "id": "A0A8V1AJL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJL7" } ] }, { "ec_number": "2.3.1.137", "activity": "", "evidence": [ { "id": "A0A8V1AJL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJL7" } ] }, { "ec_number": "2.3.1.7", "activity": "", "evidence": [ { "id": "A0A8V1AJL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJL7" } ] } ] }, { "uniprot_ac": "A0A8V1ANC5", "gene_name": "PIPOX", "activity": [ { "ec_number": "1.5.3.1", "activity": "sarcosine + O2 + H2O = formaldehyde + glycine + H2O2.", "evidence": [ { "id": "A0A8V1ANC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANC5" } ] }, { "ec_number": "1.5.3.7", "activity": "L-pipecolate + O2 = L-1-piperideine-6-carboxylate + H2O2 + H(+).", "evidence": [ { "id": "A0A8V1ANC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANC5" } ] }, { "ec_number": "1.5.3.7", "activity": "", "evidence": [ { "id": "A0A8V1ANC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANC5" } ] }, { "ec_number": "1.5.3.1", "activity": "", "evidence": [ { "id": "A0A8V1ANC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANC5" } ] } ] }, { "uniprot_ac": "E1BRR7", "gene_name": "HAO1", "activity": [ { "ec_number": "1.1.3.15", "activity": "glycolate + O2 = glyoxylate + H2O2.", "evidence": [ { "id": "E1BRR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BRR7" } ] }, { "ec_number": "1.1.3.15", "activity": "", "evidence": [ { "id": "E1BRR7", "database": "UniProtKB", "url": 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"gene_name": "AMACR", "activity": [ { "ec_number": "5.1.99.4", "activity": "a (2S)-2-methylacyl-CoA = a (2R)-2-methylacyl-CoA.", "evidence": [ { "id": "F1NKY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NKY1" } ] }, { "ec_number": "5.1.99.4", "activity": "", "evidence": [ { "id": "F1NKY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NKY1" } ] } ] }, { "uniprot_ac": "Q5ZL13", "gene_name": "NUDT19", "activity": [ { "ec_number": "3.6.1.-", "activity": "", "evidence": [ { "id": "Q5ZL13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZL13" } ] }, { "ec_number": "3.6.1.77", "activity": "CoA + H2O = (R)-4'-phosphopantetheine + adenosine 3',5'-bisphosphate + 2 H(+).", "evidence": [ { "id": "Q5ZL13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZL13" } ] }, { "ec_number": "3.6.1.77", "activity": "", "evidence": [ { "id": "Q5ZL13", "database": "UniProtKB", "url": 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"count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZNW3-1", "uniprot_ac": "A0A8V0ZNW3", "uniprot_id": "A0A8V0ZNW3_CHICK", "mass": { "chemical_mass": 70030.0, "monoisotopic_mass": 70030.0 }, "refseq": {}, "gene_names": [ { "name": "ENTPD1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZNW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNW3" } ] } ], "protein_names": [ { "name": "Ectonucleoside triphosphate diphosphohydrolase 1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZNW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNW3/entry#names_and_taxonomy" } ] }, { "name": "3.6.1.5", "type": "synonym", "evidence": [ { "id": "A0A8V0ZNW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNW3/entry#names_and_taxonomy" } ] }, { "name": "ATP diphosphohydrolase", "type": "synonym", "evidence": [ { "id": "A0A8V0ZNW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNW3/entry#names_and_taxonomy" } ] }, { "name": "Ecto-ATP diphosphohydrolase 1", "type": "synonym", "evidence": [ { "id": "A0A8V0ZNW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNW3/entry#names_and_taxonomy" } ] }, { "name": "Ecto-apyrase", "type": "synonym", "evidence": [ { "id": "A0A8V0ZNW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNW3/entry#names_and_taxonomy" } ] }, { "name": "Lymphoid cell activation antigen", "type": "synonym", "evidence": [ { "id": "A0A8V0ZNW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNW3/entry#names_and_taxonomy" } ] }, { "name": "Nucleoside triphosphate diphosphohydrolase 1", "type": "synonym", "evidence": [ { "id": "A0A8V0ZNW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNW3/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Catalyzes the hydrolysis of nucleoside triphosphates (NTPs) and diphosphates (NDPs). The enzyme sequentially removes phosphate groups in two successive steps, converting NTPs to nucleoside monophosphates (NMPs) via NDP intermediates. This activity contributes to the regulation of extracellular levels of nucleotides. By hydrolyzing proinflammatory ATP and platelet-activating ADP to AMP, it blocks platelet aggregation and supports blood flow.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNW3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNW3#function" }, { "database": "UniProtKB", "id": "ARBA00094486", "url": "https://www.uniprot.org/uniprotkb/ARBA00094486#function" }, { "database": "UniProtKB", "id": "A0A1D5PZJ5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZJ5#function" }, { "database": "UniProtKB", "id": "A0A8V0ZGD3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGD3#function" }, { "database": "UniProtKB", "id": "A0A8V0ZGE3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGE3#function" }, { "database": "UniProtKB", "id": "A0A8V0ZGF3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGF3#function" }, { "database": "UniProtKB", "id": "A0A8V0ZNG5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNG5#function" }, { "database": "UniProtKB", "id": "A0A8V0ZNK0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNK0#function" }, { "database": "UniProtKB", "id": "A0A8V0ZNU8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNU8#function" }, { "database": "UniProtKB", "id": "A0A8V0ZNV8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNV8#function" }, { "database": "UniProtKB", "id": "A0A8V0ZNY4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNY4#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNW3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNW3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ENTPD1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNW3", "locus": { "chromosome": "6", "start_pos": 22827546, "end_pos": 22780072, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022100", "url": "https://www.ensembl.org/id/ENSGALG00010022100" } ] } } ], "crossref": [ { "id": "A0A8V0ZNW3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZNW3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000007078", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000007078", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd24110", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd24110", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "423826", "url": "https://www.ncbi.nlm.nih.gov/gene/423826", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000407", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000407", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PYSHCAF", "url": "https://omabrowser.org/oma/group/PYSHCAF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PZJ5", "url": "https://www.orthodb.org/?gene=A0A1D5PZJ5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZGD3", "url": "https://www.orthodb.org/?gene=A0A8V0ZGD3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZGE3", "url": "https://www.orthodb.org/?gene=A0A8V0ZGE3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZGF3", "url": "https://www.orthodb.org/?gene=A0A8V0ZGF3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZNG5", "url": "https://www.orthodb.org/?gene=A0A8V0ZNG5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZNK0", "url": "https://www.orthodb.org/?gene=A0A8V0ZNK0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZNU8", "url": "https://www.orthodb.org/?gene=A0A8V0ZNU8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZNV8", "url": "https://www.orthodb.org/?gene=A0A8V0ZNV8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZNW3", "url": "https://www.orthodb.org/?gene=A0A8V0ZNW3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZNY4", "url": "https://www.orthodb.org/?gene=A0A8V0ZNY4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11782", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11782", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11782:SF32", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11782:SF32", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01150", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01150", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-8850843", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8850843", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "13065", "url": "https://www.rhea-db.org/rhea/13065", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "19669", "url": "https://www.rhea-db.org/rhea/19669", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "20988", "url": "https://www.rhea-db.org/rhea/20988", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "22156", "url": "https://www.rhea-db.org/rhea/22156", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "23680", "url": "https://www.rhea-db.org/rhea/23680", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "28330", "url": "https://www.rhea-db.org/rhea/28330", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "29387", "url": "https://www.rhea-db.org/rhea/29387", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "35207", "url": "https://www.rhea-db.org/rhea/35207", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "36795", "url": "https://www.rhea-db.org/rhea/36795", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "36799", "url": "https://www.rhea-db.org/rhea/36799", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "61436", "url": "https://www.rhea-db.org/rhea/61436", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "64876", "url": "https://www.rhea-db.org/rhea/64876", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "64880", "url": "https://www.rhea-db.org/rhea/64880", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "64896", "url": "https://www.rhea-db.org/rhea/64896", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "64900", "url": "https://www.rhea-db.org/rhea/64900", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "64904", "url": "https://www.rhea-db.org/rhea/64904", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "64908", "url": "https://www.rhea-db.org/rhea/64908", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "77735", "url": "https://www.rhea-db.org/rhea/77735", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A1D5PZJ5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZJ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PZJ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZJ5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZGD3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGD3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZGD3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGD3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZGE3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGE3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZGE3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGE3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZGF3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGF3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZGF3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGF3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZNG5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNG5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZNG5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNG5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZNK0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNK0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZNK0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNK0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZNU8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNU8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZNU8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNU8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZNV8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNV8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZNV8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNV8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZNW3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNW3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZNW3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNW3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZNY4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNY4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZNY4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNY4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRGQLGADVDGNSLWHEGAVRPEAGVADPRWIVRKGPEHEGLKGLLRPIWCQPMFFIWVRGGQQVGGGEGSLEASQQVTDNWLLPEAPQGMHRGVSSFRGAGTAAKMTSPPLGADDAIPLQSAAPAVTGTKPKMSTTRKILLILGFLSTLAAIALITVAVTQNQPLPKNIKYGIVLDAGSSHTNLYVYEWPAEKENDTGVVQQVEVCKVEGPGISGYSQTTEKAGPSLVQCLRQAEGVIPLKQHQETPVYLGATAGMRLLRLENKDAAEKVLSSVEKTLRSAPFNFQGARIISGQEEGAYGWITINYLLGNFKQSGWKKFLHSLKSVSETSGALDLGGASTQITFVPDEISSESPQNLLYFRLYGKDYRVYTHSFLCYGKDQALQQKLARDLQSTENSSLFDPCFHQGYQRTISVSNFFKNPCTSVEKKQFPFSQLHIEGEGNYEKCRRNIQNLFNKTDCPYSSCSFNGIYLPPLQGDFGAFSAFYFVMNFLNLTSDDPFTLDEVASAIKKFCARPWHEVKLQYHQIKEKYLSEYCFSGAYILSLLENGYEFTTENWKRIHFLGKIGSSDAGWTLGYMLNLTNMIPAEEPPAPPLSYGSYVGLMVLCSLVLVSVILLAWLLFHKPKCLQKGVV", "length": 633, "header": "tr|A0A8V0ZNW3-1|A0A8V0ZNW3_CHICK Isoform 1 of Ectonucleoside triphosphate diphosphohydrolase 1 OS=Gallus gallus OX=9031 GN=ENTPD1 PE=1 SV=1 CANONICAL=A0A8V0ZNW3-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PZJ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNW3/entry#A0A1D5PZJ5-1", "sequence": { "sequence": "MRKKQKTAWKEILKWEKEVTGTKPKMSTTRKILLILGFLSTLAAIALITVAVTQNQPLPKNIKYGIVLDAGSSHTNLYVYEWPAEKENDTGVVQQVEVCKVEGPGISGYSQTTEKAGPSLVQCLRQAEGVIPLKQHQETPVYLGATAGMRLLRLENKDAAEKVLSSVEKTLRSAPFNFQGARIISGQEEGAYGWITINYLLGNFKQSGWKKFLHSLKSVSETSGALDLGGASTQITFVPDEISSESPQNLLYFRLYGKDYRVYTHSFLCYGKDQALQQKLARDLQSTENSSLFDPCFHQGYQRTISVSNFFKNPCTSVEKKQFPFSQLHIEGEGNYEKCRRNIQNLFNKTDCPYSSCSFNGIYLPPLQGDFGAFSAFYFVMNFLNLTSDDPFTLDEVASAIKKFCARPWHEVKLQYHQIKEKYLSEYCFSGAYILSLLENGYEFTTENWKRIHFLGKIGSSDAGWTLGYMLNLTNMIPAEEPPAPPLSYGSYVGLMVLCSLVLVSVILLAWLLFHKPKCLQKGVV", "length": 525, "header": "tr|A0A1D5PZJ5-1|A0A8V0ZNW3_CHICK Computationally mapped isoform of Ectonucleoside triphosphate diphosphohydrolase 1 OS=Gallus gallus OX=9031 GN=ENTPD1 PE=1 SV=1 CANONICAL=A0A8V0ZNW3-1" }, "locus": { "chromosome": "6", "start_pos": 22823712, "end_pos": 22788137, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053800.1", "url": "https://www.ensembl.org/id/ENSGALT00010053800.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032389.1", "url": "https://www.ensembl.org/id/ENSGALP00010032389.1" } ] } }, { "isoform_ac": "A0A8V0ZGD3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNW3/entry#A0A8V0ZGD3-1", "sequence": { "sequence": "MKKGDSSADSWSFSVVIETKTELWKKLVLVPCKHCLEHRNMPEDFWGGYGIVLDAGSSHTNLYVYEWPAEKENDTGVVQQVEVCKVEGPGISGYSQTTEKAGPSLVQCLRQAEGVIPLKQHQETPVYLGATAGMRLLRLENKDAAEKVLSSVEKTLRSAPFNFQGARIISGQEEGAYGWITINYLLGNFKQSGWKKFLHSLKSVSETSGALDLGGASTQITFVPDEISSESPQNLLYFRLYGKDYRVYTHSFLCYGKDQALQQKLARDLQSTENSSLFDPCFHQGYQRTISVSNFFKNPCTSVEKKQFPFSQLHIEGEGNYEKCRRNIQNLFNKTDCPYSSCSFNGIYLPPLQGDFGAFSAFYFVMNFLNLTSDDPFTLDEVASAIKKFCARPWHEVKLQYHQIKEKYLSEYCFSGAYILSLLENGYEFTTENWKRIHFLGKIGSSDAGWTLGYMLNLTNMIPAEEPPAPPLSYGSYVGLMVLCSLVLVSVILLAWLLFHKPKCLQKGVV", "length": 510, "header": "tr|A0A8V0ZGD3-1|A0A8V0ZGD3_CHICK Computationally mapped isoform of Ectonucleoside triphosphate diphosphohydrolase 1 OS=Gallus gallus OX=9031 GN=ENTPD1 PE=1 SV=1 CANONICAL=A0A8V0ZNW3-1" }, "locus": { "chromosome": "6", "start_pos": 22823712, "end_pos": 22809604, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053763.1", "url": "https://www.ensembl.org/id/ENSGALT00010053763.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032372.1", "url": "https://www.ensembl.org/id/ENSGALP00010032372.1" } ] } }, { "isoform_ac": "A0A8V0ZGE3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNW3/entry#A0A8V0ZGE3-1", "sequence": { "sequence": "MRKKQKTAWKEILKWEKEAKMTSPPLGADDAIPLQSAAPAVTGTKPKMSTTRKILLILGFLSTLAAIALITVAVTQNQPLPKNIKYGIVLDAGSSHTNLYVYEWPAEKENDTGVVQQVEVCKVEGPGISGYSQTTEKAGPSLVQCLRQAEGVIPLKQHQETPVYLGATAGMRLLRLENKDAAEKVLSSVEKTLRSAPFNFQGARIISGQEEGAYGWITINYLLGNFKQSGWKKFLHSLKSVSETSGALDLGGASTQITFVPDEISSESPQNLLYFRLYGKDYRVYTHSFLCYGKDQALQQKLARDLQSTENSSLFDPCFHQGYQRTISVSNFFKNPCTSVEKKQFPFSQLHIEGEGNYEKCRRNIQNLFNKTDCPYSSCSFNGIYLPPLQGDFGAFSAFYFVMNFLNLTSDDPFTLDEVASAIKKFCARPWHEVKLQYHQIKEKYLSEYCFSGAYILSLLENGYEFTTENWKRIHFLGKIGSSDAGWTLGYMLNLTNMIPAEEPPAPPLSYGSYVGLMVLCSLVLVSVILLAWLLFHKPKCLQKGVV", "length": 547, "header": "tr|A0A8V0ZGE3-1|A0A8V0ZGE3_CHICK Computationally mapped isoform of Ectonucleoside triphosphate diphosphohydrolase 1 OS=Gallus gallus OX=9031 GN=ENTPD1 PE=1 SV=1 CANONICAL=A0A8V0ZNW3-1" }, "locus": { "chromosome": "6", "start_pos": 22823712, "end_pos": 22788137, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053788.1", "url": "https://www.ensembl.org/id/ENSGALT00010053788.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032382.1", "url": "https://www.ensembl.org/id/ENSGALP00010032382.1" } ] } }, { "isoform_ac": "A0A8V0ZGF3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNW3/entry#A0A8V0ZGF3-1", "sequence": { "sequence": "MERDTEMGERSQNDLSPSRSRRCDPASERSPRRRLKAGGGLERKRERETGRRERASALMDEPKVTGTKPKMSTTRKILLILGFLSTLAAIALITVAVTQNQPLPKNIKYGIVLDAGSSHTNLYVYEWPAEKENDTGVVQQVEVCKVEGPGISGYSQTTEKAGPSLVQCLRQAEGVIPLKQHQETPVYLGATAGMRLLRLENKDAAEKVLSSVEKTLRSAPFNFQGARIISGQEEGAYGWITINYLLGNFKQSGWKKFLHSLKSVSETSGALDLGGASTQITFVPDEISSESPQNLLYFRLYGKDYRVYTHSFLCYGKDQALQQKLARDLQSTENSSLFDPCFHQGYQRTISVSNFFKNPCTSVEKKQFPFSQLHIEGEGNYEKCRRNIQNLFNKTDCPYSSCSFNGIYLPPLQGDFGAFSAFYFVMNFLNLTSDDPFTLDEVASAIKKFCARPWHEVKLQYHQIKEKYLSEYCFSGAYILSLLENGYEFTTENWKRIHFLGKIGSSDAGWTLGYMLNLTNMIPAEEPPAPPLSYGSYVGLMVLCSLVLVSVILLAWLLFHKPKCLQKGVV", "length": 570, "header": "tr|A0A8V0ZGF3-1|A0A8V0ZGF3_CHICK Computationally mapped isoform of Ectonucleoside triphosphate diphosphohydrolase 1 OS=Gallus gallus OX=9031 GN=ENTPD1 PE=1 SV=1 CANONICAL=A0A8V0ZNW3-1" }, "locus": { "chromosome": "6", "start_pos": 22823712, "end_pos": 22788160, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053807.1", "url": "https://www.ensembl.org/id/ENSGALT00010053807.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032392.1", "url": "https://www.ensembl.org/id/ENSGALP00010032392.1" } ] } }, { "isoform_ac": "A0A8V0ZNG5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNW3/entry#A0A8V0ZNG5-1", "sequence": { "sequence": "MKYRGAGGGWGTLTGTKPKMSTTRKILLILGFLSTLAAIALITVAVTQNQPLPKNIKYGIVLDAGSSHTNLYVYEWPAEKENDTGVVQQVEVCKVEGPGISGYSQTTEKAGPSLVQCLRQAEGVIPLKQHQETPVYLGATAGMRLLRLENKDAAEKVLSSVEKTLRSAPFNFQGARIISGQEEGAYGWITINYLLGNFKQSGWKKFLHSLKSVSETSGALDLGGASTQITFVPDEISSESPQNLLYFRLYGKDYRVYTHSFLCYGKDQALQQKLARDLQSTENSSLFDPCFHQGYQRTISVSNFFKNPCTSVEKKQFPFSQLHIEGEGNYEKCRRNIQNLFNKTDCPYSSCSFNGIYLPPLQGDFGAFSAFYFVMNFLNLTSDDPFTLDEVASAIKKFCARPWHEVKLQYHQIKEKYLSEYCFSGAYILSLLENGYEFTTENWKRIHFLGKIGSSDAGWTLGYMLNLTNMIPAEEPPAPPLSYGSYVGLMVLCSLVLVSVILLAWLLFHKPKCLQKGVV", "length": 519, "header": "tr|A0A8V0ZNG5-1|A0A8V0ZNG5_CHICK Computationally mapped isoform of Ectonucleoside triphosphate diphosphohydrolase 1 OS=Gallus gallus OX=9031 GN=ENTPD1 PE=1 SV=1 CANONICAL=A0A8V0ZNW3-1" }, "locus": { "chromosome": "6", "start_pos": 22823712, "end_pos": 22815478, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053742.1", "url": "https://www.ensembl.org/id/ENSGALT00010053742.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032361.1", "url": "https://www.ensembl.org/id/ENSGALP00010032361.1" } ] } }, { "isoform_ac": "A0A8V0ZNK0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNW3/entry#A0A8V0ZNK0-1", "sequence": { "sequence": "MTSPPLGADDAIPLQSAAPAVTGTKPKMSTTRKILLILGFLSTLAAIALITVAVTQNQPLPKNIKYGIVLDAGSSHTNLYVYEWPAEKENDTGVVQQVEVCKVEGPGISGYSQTTEKAGPSLVQCLRQAEGVIPLKQHQETPVYLGATAGMRLLRLENKDAAEKVLSSVEKTLRSAPFNFQGARIISGQEEGAYGWITINYLLGNFKQSGWKKFLHSLKSVSETSGALDLGGASTQITFVPDEISSESPQNLLYFRLYGKDYRVYTHSFLCYGKDQALQQKLARDLQSTENSSLFDPCFHQGYQRTISVSNFFKNPCTSVEKKQFPFSQLHIEGEGNYEKCRRNIQNLFNKTDCPYSSCSFNGIYLPPLQGDFGAFSAFYFVMNFLNLTSDDPFTLDEVASAIKKFCARPWHEVKLQYHQIKEKYLSEYCFSGAYILSLLENGYEFTTENWKRIHFLGKIGSSDAGWTLGYMLNLTNMIPAEEPPAPPLSYGSYVGLMVLCSLVLVSVILLAWLLFHKPKCLQKGVV", "length": 527, "header": "tr|A0A8V0ZNK0-1|A0A8V0ZNK0_CHICK Computationally mapped isoform of Ectonucleoside triphosphate diphosphohydrolase 1 OS=Gallus gallus OX=9031 GN=ENTPD1 PE=1 SV=1 CANONICAL=A0A8V0ZNW3-1" }, "locus": { "chromosome": "6", "start_pos": 22823712, "end_pos": 22797633, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053818.1", "url": "https://www.ensembl.org/id/ENSGALT00010053818.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032396.1", "url": "https://www.ensembl.org/id/ENSGALP00010032396.1" } ] } }, { "isoform_ac": "A0A8V0ZNU8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNW3/entry#A0A8V0ZNU8-1", "sequence": { "sequence": "MCFVCRAKGCLSAGPAALNSLTWLLWHKGCETDLHKAPQGHFQLRRWLWAGREGPCVMPAPLFPFLATTAQLSQHSPVLQECVTGTKPKMSTTRKILLILGFLSTLAAIALITVAVTQNQPLPKNIKYGIVLDAGSSHTNLYVYEWPAEKENDTGVVQQVEVCKVEGPGISGYSQTTEKAGPSLVQCLRQAEGVIPLKQHQETPVYLGATAGMRLLRLENKDAAEKVLSSVEKTLRSAPFNFQGARIISGQEEGAYGWITINYLLGNFKQSGWKKFLHSLKSVSETSGALDLGGASTQITFVPDEISSESPQNLLYFRLYGKDYRVYTHSFLCYGKDQALQQKLARDLQSTENSSLFDPCFHQGYQRTISVSNFFKNPCTSVEKKQFPFSQLHIEGEGNYEKCRRNIQNLFNKTDCPYSSCSFNGIYLPPLQGDFGAFSAFYFVMNFLNLTSDDPFTLDEVASAIKKFCARPWHEVKLQYHQIKEKYLSEYCFSGAYILSLLENGYEFTTENWKRIHFLGKIGSSDAGWTLGYMLNLTNMIPAEEPPAPPLSYGSYVGLMVLCSLVLVSVILLAWLLFHKPKCLQKGVV", "length": 589, "header": "tr|A0A8V0ZNU8-1|A0A8V0ZNU8_CHICK Computationally mapped isoform of Ectonucleoside triphosphate diphosphohydrolase 1 OS=Gallus gallus OX=9031 GN=ENTPD1 PE=1 SV=1 CANONICAL=A0A8V0ZNW3-1" }, "locus": { "chromosome": "6", "start_pos": 22823712, "end_pos": 22811928, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053751.1", "url": "https://www.ensembl.org/id/ENSGALT00010053751.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032365.1", "url": "https://www.ensembl.org/id/ENSGALP00010032365.1" } ] } }, { "isoform_ac": "A0A8V0ZNV8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNW3/entry#A0A8V0ZNV8-1", "sequence": { "sequence": "MATPFGMRGLLGPRQGLRIQDGLSGKAPQGMHRGVSSFRGAGTAAKMTSPPLGADDAIPLQSAAPAVTGTKPKMSTTRKILLILGFLSTLAAIALITVAVTQNQPLPKNIKYGIVLDAGSSHTNLYVYEWPAEKENDTGVVQQVEVCKVEGPGISGYSQTTEKAGPSLVQCLRQAEGVIPLKQHQETPVYLGATAGMRLLRLENKDAAEKVLSSVEKTLRSAPFNFQGARIISGQEEGAYGWITINYLLGNFKQSGWKKFLHSLKSVSETSGALDLGGASTQITFVPDEISSESPQNLLYFRLYGKDYRVYTHSFLCYGKDQALQQKLARDLQSTENSSLFDPCFHQGYQRTISVSNFFKNPCTSVEKKQFPFSQLHIEGEGNYEKCRRNIQNLFNKTDCPYSSCSFNGIYLPPLQGDFGAFSAFYFVMNFLNLTSDDPFTLDEVASAIKKFCARPWHEVKLQYHQIKEKYLSEYCFSGAYILSLLENGYEFTTENWKRIHFLGKIGSSDAGWTLGYMLNLTNMIPAEEPPAPPLSYGSYVGLMVLCSLVLVSVILLAWLLFHKPKCLQKGVV", "length": 573, "header": "tr|A0A8V0ZNV8-1|A0A8V0ZNV8_CHICK Computationally mapped isoform of Ectonucleoside triphosphate diphosphohydrolase 1 OS=Gallus gallus OX=9031 GN=ENTPD1 PE=1 SV=1 CANONICAL=A0A8V0ZNW3-1" }, "locus": { "chromosome": "6", "start_pos": 22823712, "end_pos": 22797182, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053771.1", "url": "https://www.ensembl.org/id/ENSGALT00010053771.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032375.1", "url": "https://www.ensembl.org/id/ENSGALP00010032375.1" } ] } }, { "isoform_ac": "A0A8V0ZNW3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNW3/entry#A0A8V0ZNW3-1", "sequence": { "sequence": "MRGQLGADVDGNSLWHEGAVRPEAGVADPRWIVRKGPEHEGLKGLLRPIWCQPMFFIWVRGGQQVGGGEGSLEASQQVTDNWLLPEAPQGMHRGVSSFRGAGTAAKMTSPPLGADDAIPLQSAAPAVTGTKPKMSTTRKILLILGFLSTLAAIALITVAVTQNQPLPKNIKYGIVLDAGSSHTNLYVYEWPAEKENDTGVVQQVEVCKVEGPGISGYSQTTEKAGPSLVQCLRQAEGVIPLKQHQETPVYLGATAGMRLLRLENKDAAEKVLSSVEKTLRSAPFNFQGARIISGQEEGAYGWITINYLLGNFKQSGWKKFLHSLKSVSETSGALDLGGASTQITFVPDEISSESPQNLLYFRLYGKDYRVYTHSFLCYGKDQALQQKLARDLQSTENSSLFDPCFHQGYQRTISVSNFFKNPCTSVEKKQFPFSQLHIEGEGNYEKCRRNIQNLFNKTDCPYSSCSFNGIYLPPLQGDFGAFSAFYFVMNFLNLTSDDPFTLDEVASAIKKFCARPWHEVKLQYHQIKEKYLSEYCFSGAYILSLLENGYEFTTENWKRIHFLGKIGSSDAGWTLGYMLNLTNMIPAEEPPAPPLSYGSYVGLMVLCSLVLVSVILLAWLLFHKPKCLQKGVV", "length": 633, "header": "tr|A0A8V0ZNW3-1|A0A8V0ZNW3_CHICK Isoform 1 of Ectonucleoside triphosphate diphosphohydrolase 1 OS=Gallus gallus OX=9031 GN=ENTPD1 PE=1 SV=1 CANONICAL=A0A8V0ZNW3-1" }, "locus": { "chromosome": "6", "start_pos": 22823712, "end_pos": 22797154, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053781.1", "url": "https://www.ensembl.org/id/ENSGALT00010053781.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032380.1", "url": "https://www.ensembl.org/id/ENSGALP00010032380.1" } ] } }, { "isoform_ac": "A0A8V0ZNY4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNW3/entry#A0A8V0ZNY4-1", "sequence": { "sequence": "MHLTLCIYISQNDLSPSRSRRCDPASERSPRSFSVVIETKTELWKKLVLVPCKHCLEHRNMPEDFWGGYGIVLDAGSSHTNLYVYEWPAEKENDTGVVQQVEVCKVEGPGISGYSQTTEKAGPSLVQCLRQAEGVIPLKQHQETPVYLGATAGMRLLRLENKDAAEKVLSSVEKTLRSAPFNFQGARIISGQEEGAYGWITINYLLGNFKQSGWKKFLHSLKSVSETSGALDLGGASTQITFVPDEISSESPQNLLYFRLYGKDYRVYTHSFLCYGKDQALQQKLARDLQSTENSSLFDPCFHQGYQRTISVSNFFKNPCTSVEKKQFPFSQLHIEGEGNYEKCRRNIQNLFNKTDCPYSSCSFNGIYLPPLQGDFGAFSAFYFVMNFLNLTSDDPFTLDEVASAIKKFCARPWHEVKLQYHQIKEKYLSEYCFSGAYILSLLENGYEFTTENWKRIHFLGKIGSSDAGWTLGYMLNLTNMIPAEEPPAPPLSYGSYVGLMVLCSLVLVSVILLAWLLFHKPKCLQKGVV", "length": 530, "header": "tr|A0A8V0ZNY4-1|A0A8V0ZNY4_CHICK Computationally mapped isoform of Ectonucleoside triphosphate diphosphohydrolase 1 OS=Gallus gallus OX=9031 GN=ENTPD1 PE=1 SV=1 CANONICAL=A0A8V0ZNW3-1" }, "locus": { "chromosome": "6", "start_pos": 22823712, "end_pos": 22780336, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053823.1", "url": "https://www.ensembl.org/id/ENSGALT00010053823.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032400.1", "url": "https://www.ensembl.org/id/ENSGALP00010032400.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-GGA-8850843", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8850843", "resource": "Reactome", "description": "Phosphate bond hydrolysis by NTPDase proteins" } ], "orthologs": [ { "uniprot_canonical_ac": "F1MB25-1", "protein_name": "Ectonucleoside triphosphate diphosphohydrolase 1", "gene_name": "ENTPD1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MEDRRESELKVFCSKNILSILGFSCIIAVIALLALGLTQNKALPENVKFGIVLDAGSSHTSLYIYRWPAEKENDTGVVTQIEECKLKGPGISGFAKKVNEINVYLTACMERAQKVIPSIQHMETPVYLGATAGMRLLRMENKQMADKILAAVASSISKYPFDFQGARIISGQEEGAYGWITVNYLLGKFTQKLSWFNLKPSKDDTQETYGALDLGGASTQITFVPQNETTESPNNNLYFRLYGKNYSVYTHSFLCYGKDQALLQKLALGLQGTNGIIHEPCFHSRYMRKIKMSVLNEGFCTKRHELNSSFYPLVDIEIRGAGNFQRCRQSIIQLFNTSYCPYSSCSFNGVFLPPLHGQFGAFSAFYYVMEFLNLTSEESVSVEQLTEKLEEFCAQRWEEVQKNFGEVKEKYLSEYCFSGTYILVLLLNGYHFTAESWKNIHFMNKVRSTSVGWTLGYMLNLTNKIPAEEPMSPPLPHSTYVFLMVLFSLILLAVIIVGIVVFHKPSYFWKDMV", "length": 513 }, "evidence": [ { "id": "A0A8V0ZNW3", "url": "https://omabrowser.org/oma/group/A0A8V0ZNW3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1SC45-1", "protein_name": "Ectonucleoside triphosphate diphosphohydrolase 1", "gene_name": "ENTPD1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEDRRESELKTFCSKNILVILGFSSIIAVIALLALGLTQNKPLPENVKFGIVLDAGSSHTSLYIYKWPAEKENDTGVVSQVEECKLKGPGISEFAKKLGEIDIYLEACMERARTVVPKSQHAETPVYLGATAGMRLLRMKNENLASKILSTVAESITRYPFDFQGARIITGQEEGAYGWITINYLLDKFIQKSGWFNLKPRKGDTQETYGALDLGGASTQITFVPQNQVLESPENTLHFRLYGKNYSVYTHSFLCYGKDQALLQKLTKDLKNTNGTIHEPCFHSGYQRRMNVSHLYEAPCTRRFLTSLPFPELEIQGTGDFQKCQQSIRPLFNTSYCPYSRCSFDGVFLPLPQGDFAAFSAFYYVMGFLNLTSEEGSSQSKVTSTLEAFCSRPWAELQMYFGDVKEKYLSEYCFSGTYILTLLLSGYHFTAETWKNIHFMGKVQSTSVGWTLGYMLNLTNMIPSEEPSSTRLSHSTYVFLMVLFSLILVIVVIIGLFVCHRPSYFWKDMV", "length": 510 }, "evidence": [ { "id": "A0A8V0ZNW3", "url": "https://omabrowser.org/oma/group/A0A8V0ZNW3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P49961-1", "protein_name": "Ectonucleoside triphosphate diphosphohydrolase 1", "gene_name": "ENTPD1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEDTKESNVKTFCSKNILAILGFSSIIAVIALLAVGLTQNKALPENVKYGIVLDAGSSHTSLYIYKWPAEKENDTGVVHQVEECRVKGPGISKFVQKVNEIGIYLTDCMERAREVIPRSQHQETPVYLGATAGMRLLRMESEELADRVLDVVERSLSNYPFDFQGARIITGQEEGAYGWITINYLLGKFSQKTRWFSIVPYETNNQETFGALDLGGASTQVTFVPQNQTIESPDNALQFRLYGKDYNVYTHSFLCYGKDQALWQKLAKDIQVASNEILRDPCFHPGYKKVVNVSDLYKTPCTKRFEMTLPFQQFEIQGIGNYQQCHQSILELFNTSYCPYSQCAFNGIFLPPLQGDFGAFSAFYFVMKFLNLTSEKVSQEKVTEMMKKFCAQPWEEIKTSYAGVKEKYLSEYCFSGTYILSLLLQGYHFTADSWEHIHFIGKIQGSDAGWTLGYMLNLTNMIPAEQPLSTPLSHSTYVFLMVLFSLVLFTVAIIGLLIFHKPSYFWKDMV", "length": 510 }, "evidence": [ { "id": "A0A8V0ZNW3", "url": "https://omabrowser.org/oma/group/A0A8V0ZNW3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P55772-1", "protein_name": "Ectonucleoside triphosphate diphosphohydrolase 1", "gene_name": "Entpd1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEDIKDSKVKRFCSKNILIILGFTSILAVIALIAVGLTQNKPLPENVKYGIVLDAGSSHTNLYIYKWPAEKENDTGVVQQLEECQVKGPGISKYAQKTDEIGAYLAECMELSTELIPTSKHHQTPVYLGATAGMRLLRMESEQSADEVLAAVSTSLKSYPFDFQGAKIITGQEEGAYGWITINYLLGRFTQEQSWLSLISDSQKQETFGALDLGGASTQITFVPQNSTIESPENSLQFRLYGEDYTVYTHSFLCYGKDQALWQKLAKDIQVSSGGVLKDPCFNPGYEKVVNVSELYGTPCTKRFEKKLPFDQFRIQGTGDYEQCHQSILELFNNSHCPYSQCAFNGVFLPPLHGSFGAFSAFYFVMDFFKKVAKNSVISQEKMTEITKNFCSKSWEETKTSYPSVKEKYLSEYCFSGAYILSLLQGYNFTDSSWEQIHFMGKIKDSNAGWTLGYMLNLTNMIPAEQPLSPPLPHSTYIGLMVLFSLLLVAVAITGLFIYSKPSYFWKEAV", "length": 510 }, "evidence": [ { "id": "A0A8V0ZNW3", "url": "https://omabrowser.org/oma/group/A0A8V0ZNW3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P97687-1", "protein_name": "Ectonucleoside triphosphate diphosphohydrolase 1", "gene_name": "Entpd1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEDIKDSKVKRFCSKNILIILGFSSVLAVIALIAVGLTHNKPLPENVKYGIVLDAGSSHTNLYIYKWPAEKENDTGVVQLLEECQVKGPGISKYAQKTDEIAAYLAECMKMSTERIPASKQHQTPVYLGATAGMRLLRMESKQSADEVLAAVSRSLKSYPFDFQGAKIITGQEEGAYGWITINYLLGRFTQEQSWLNFISDSQKQATFGALDLGGSSTQVTFVPLNQTLEAPETSLQFRLYGTDYTVYTHSFLCYGKDQALWQKLAQDIQVSSGGILKDPCFYPGYKKVVNVSELYGTPCTKRFEKKLPFNQFQVQGTGDYEQCHQSILKFFNNSHCPYSQCAFNGVFLPPLQGSFGAFSAFYFVMDFFKKMANDSVSSQEKMTEITKNFCSKPWEEVKASYPTVKEKYLSEYCFSGTYILSLLLQGYNFTGTSWDQIHFMGKIKDSNAGWTLGYMLNLTNMIPAEQPLSPPLPHSTYISLMVLFSLVLVAMVITGLFIFSKPSYFWKEAV", "length": 511 }, "evidence": [ { "id": "A0A8V0ZNW3", "url": "https://omabrowser.org/oma/group/A0A8V0ZNW3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNW3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNW3" } ], "pmid": "" }, { "name": "apyrase activity", "id": "GO:0004050", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004050", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNW3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNW3" } ], "pmid": "" }, { "name": "GDP phosphatase activity", "id": "GO:0004382", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004382", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNW3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNW3" } ], "pmid": "" }, { "name": "UDP phosphatase activity", "id": "GO:0045134", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045134", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNW3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNW3" } ], "pmid": "" }, { "name": "ribonucleoside triphosphate phosphatase activity", "id": "GO:0017111", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017111", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNW3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNW3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "caveola", "id": "GO:0005901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005901", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNW3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNW3" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNW3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNW3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "platelet aggregation", "id": "GO:0070527", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070527", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNW3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNW3" } ], "pmid": "" }, { "name": "nucleoside diphosphate catabolic process", "id": "GO:0009134", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009134", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNW3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNW3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 196, "end_pos": 198, "annotation": "n_glycosylation_sequon" }, { "start_pos": 397, "end_pos": 399, "annotation": "n_glycosylation_sequon" }, { "start_pos": 456, "end_pos": 458, "annotation": "n_glycosylation_sequon" }, { "start_pos": 493, "end_pos": 495, "annotation": "n_glycosylation_sequon" }, { "start_pos": 580, "end_pos": 582, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "13065", "name": "", "equation": "ATP + H2O = ADP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZC95-1", "A0A1D5PHB6-1", "A0A8V0XJV9-1", "A0A8V0ZFN9-1", "A0A1D5PIN7-1", "A0A8V0XT73-1", "A0A8V0XZB8-1", "A0A8V1AJ43-1", "A0A8V0ZU49-1", "P53478-1", "Q5F485-1", "Q5ZHZ0-1", "Q5ZI74-1", "Q5ZIW1-1", "Q5ZKB9-1", "Q5ZM36-1", "Q5ZMN2-1", "A0A8V0XLC7-1", "F1NFJ0-1", "A0A8V0YT68-1", "A0A1D5NTY5-1", "A0A8V0YU49-1", "A0A8V0YHC8-1", "A0A8V0ZPN6-1", "Q5ZJF6-1", "Q5ZKB7-1", "Q8JFP1-1", "A0A8V0YUW3-1", "Q5ZLN8-1", "E1BY42-1", "F1N8Z4-1", "F1NHI3-1", "A0A8V0XI26-1", "A0A8V0XEC4-1", "A0A8V0Y1J8-1", "A0A8V0Y242-1", "A0A8V0X9Z6-1", "A0A8V0Z289-1", "A0A8V0YFB8-1", "A0A8V0YFG2-1", "A0A8V0YNF9-1", "F1N991-1", "A0A8V0ZZF5-1", "A0A8V1ACD8-1", "A0A8V0ZUT3-1", "A0A8V0ZNU6-1", "A0A1D5P5I0-1", "A0A8V0ZZK3-1", "A0A8V1A3M1-1", "A0A8V1AJY9-1", "A0A8V1A712-1", "A0A8V1A7M6-1", "A0A3S5ZPN3-1", "A0A8V1A4V3-1", "A0A8V1AER6-1", "A0A8V1AL41-1", "A0A8V1A5D6-1", "A0A1D5PRR9-1", "A0A8V0Y0A4-1", "Q5ZKK7-1", "A0A8V1AFG8-1", "A0A8V0ZWH7-1", "A0A8V0YLM0-1", "A0A8V0ZNW3-1", "F1ND48-1", "F1NQJ3-1", "P08023-1", "P60706-1", "P63270-1", "P68034-1", "P68139-1", "Q5ZJT0-1", "Q5ZMQ2-1", "Q90593-1", "Q92058-1", "Q9I920-1", "Q90WU3-1", "A0A8V0ZVY2-1", "A0A8V0ZPM1-1", "Q3YK19-1", "E1BSC0-1", "A0A8V0X9Y7-1", "Q5ZM98-1", "F1NZ23-1", "A0A8V0YUG9-1", "F1NN44-1", "P08110-1", "F1NTD6-1", "A0A8V0Z655-1", "A0A8V1ALH0-1", "B6ZLK2-1", "A0A8V0YLC1-1", "Q06A37-1", "A0A8V0YGQ1-1", "A0A1D5PD32-1", "Q6EE31-1", "A0A8V0XX13-1", "A0A8V0YCY8-1", "A0A8V0Z5P2-1", "A0A8V0ZUQ0-1", "A0A8V1ADZ7-1", "A0A8V0XG98-1", "A0A8V0ZR10-1", "A0A8V1AFJ9-1", "Q5ZJ54-1", "Q5ZJK8-1", "A0A8V0Y005-1", "A0A8V0YAA4-1", "A0A8V0XGV3-1", "A0A8V0X600-1", "Q5ZM73-1", "Q5ZM83-1", "A0A8V0ZUR5-1", "A0A8V0ZE45-1", "A0A8V0ZEN5-1", "F1NA92-1", "A0A8V0ZTR5-1", "A0A8V1A7P4-1", "A0A8V1AIK2-1", "F1P5C0-1", "A0A8V0XHD1-1", "A0A8V0X655-1", "A0A8V0XMP8-1", "A0A8V0YUC5-1", "A0A8V0Z1F9-1", "A0A8V0Z659-1", "A0A8V0YRH6-1", "A0A8V0ZS56-1", "I0IUP3-1", "I0IUP4-1", "O93257-1", "O93295-1", "A0A8V0ZIP8-1", "Q9DG67-1", "P37383-1", "Q5ZKG3-1", "P79784-1", "A0A1D5PS27-1", "A0A1D5PVS9-1", "A0A8V1AE46-1", "A0A8V1A8Y2-1", "A0A8V1AKU6-1", "O12944-1", "A0A8V0YQS3-1", "A0A8V0Z2M8-1" ], "evidence": [ { "id": "13065", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/13065" } ] }, { "id": "19669", "name": "", "equation": "GTP + H2O = GDP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YVX9-1", "F1NSA8-1", "R4GJA4-1", "A0A1L1RKZ0-1", "E1BUS1-1", "Q5ZHW4-1", "Q90694-1", "P08070-1", "P09642-1", "P09643-1", "P09644-1", "P09645-1", "Q5F352-1", "Q5ZMS3-1", "Q90705-1", "Q90835-1", "Q90965-1", "Q98932-1", "A0A3Q2UHM4-1", "Q5ZHX1-1", "A0A1D5PT95-1", "E1BQI2-1", "F1NPF0-1", "A0A8V0XVU5-1", "A0A8V0XBX5-1", "A0A8V0Z564-1", "A0A8V0Y9R6-1", "A0A1D5PM27-1", "A0A8V0Z8U4-1", "A0A8V0ZJW2-1", "A0A8V1ABB1-1", "A0A8V0YDX6-1", "E1BWN3-1", "Q5F499-1", "Q5ZKU5-1", "P02552-1", "P08642-1", "P26990-1", "P42558-1", "Q5F470-1", "Q5ZIT5-1", "Q5ZJN2-1", "P50146-1", "A0A8V0ZNW3-1", "A0A8V0YIM0-1", "A0A8V0ZRZ2-1", "A0A8V1A9Z8-1", "Q1KME6-1", "Q5ZLG1-1", "P84172-1", "A0A8V1ACG4-1", "A0A8V0YTL7-1", "A0A3Q2UG55-1", "A0A8V1AIF5-1", "Q5ZHV1-1", "A0A8V0Z5P2-1", "A0A8V0Y4A4-1", "A0A8V0YA62-1", "A0A8V0YVM3-1", "A0A1D5P1F5-1", "A0A8V1ADZ7-1", "F1NWF1-1", "A0A8V1AP30-1", "A0A8V0XDD5-1", "A0A8V0XMC5-1", "A0A8V0YWW1-1", "A0A8V0ZR14-1", "A0A8V0Y2H3-1", "Q5ZJD3-1", "Q5ZM73-1", "Q5ZM83-1", "A0A8V0YTY9-1", "A0A8V0ZXW3-1", "A0A8V1AHB3-1", "A0A8V0YDI7-1", "A0A1D5NV13-1", "A0A8V0XGK7-1", "A0A8V0YHK2-1", "A0A8V0XC33-1", "A0A8V0XKC3-1", "F1P278-1", "A0A8V0ZG00-1", "A0A8V1AGP3-1", "A0A8V1AN75-1", "A0A8V0Z416-1", "A0A8V1A0V4-1", "A0A8V1A8Q7-1", "A0A8V1ABD3-1", "A0A8V1API8-1", "A0A8V0YIU8-1", "A0A8V0X962-1", "A0A8V1AKH3-1", "P79784-1", "A0A1D5P533-1", "A0A8V1A8I5-1", "A0A8V1AE09-1", "Q9PSX7-1", "Q5ZKR4-1", "A0A8V0YGN8-1", "A0A8V0XNL0-1", "A0A8V0Y3H2-1" ], "evidence": [ { "id": "19669", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/19669" } ] }, { "id": "20988", "name": "", "equation": "ATP + 2 H2O = AMP + 2 phosphate + 2 H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZNW3-1", "O93295-1", "P79784-1", "A0A1D5PS27-1", "A0A1D5PVS9-1", "A0A8V1AE46-1", "A0A8V1A8Y2-1" ], "evidence": [ { "id": "20988", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/20988" } ] }, { "id": "22156", "name": "", "equation": "GDP + H2O = GMP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XQY2-1", "A0A8V0ZNW3-1", "E1C1L6-1", "P79784-1" ], "evidence": [ { "id": "22156", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/22156" } ] }, { "id": "23680", "name": "", "equation": "a ribonucleoside 5'-triphosphate + H2O = a ribonucleoside 5'-diphosphate + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZNW3-1", "F1P5C0-1", "O93295-1", "P79784-1", "A0A1D5PS27-1", "A0A1D5PVS9-1", "A0A8V1AE46-1", "A0A8V1A8Y2-1" ], "evidence": [ { "id": "23680", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/23680" } ] }, { "id": "28330", "name": "", "equation": "ITP + H2O = IDP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZNW3-1", "P79784-1" ], "evidence": [ { "id": "28330", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/28330" } ] }, { "id": "29387", "name": "", "equation": "CTP + H2O = CDP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZNW3-1", "P79784-1" ], "evidence": [ { "id": "29387", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/29387" } ] }, { "id": "35207", "name": "", "equation": "IDP + H2O = IMP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XQY2-1", "A0A8V0ZNW3-1", "E1C1L6-1", "P79784-1" ], "evidence": [ { "id": "35207", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/35207" } ] }, { "id": "36795", "name": "", "equation": "a ribonucleoside 5'-triphosphate + 2 H2O = a ribonucleoside 5'-phosphate + 2 phosphate + 2 H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "O93295-1", "A0A8V1AE46-1", "A0A8V1A8Y2-1", "A0A8V0ZNW3-1", "P79784-1", "A0A1D5PS27-1", "A0A1D5PVS9-1" ], "evidence": [ { "id": "36795", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/36795" } ] }, { "id": "36799", "name": "", "equation": "a ribonucleoside 5'-diphosphate + H2O = a ribonucleoside 5'-phosphate + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XQY2-1", "A0A8V0ZNW3-1", "E1C1L6-1", "A0A8V1AMW1-1", "O93295-1", "P79784-1", "A0A1D5PS27-1", "A0A1D5PVS9-1", "A0A8V1AE46-1", "A0A8V1A8Y2-1" ], "evidence": [ { "id": "36799", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/36799" } ] }, { "id": "61436", "name": "", "equation": "ADP + H2O = AMP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XQY2-1", "A0A8V0ZNW3-1", "E1C1L6-1", "Q92058-1", "F1NN44-1", "O93295-1", "P79784-1", "A0A8V1AE46-1", "A0A8V1A8Y2-1" ], "evidence": [ { "id": "61436", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/61436" } ] }, { "id": "64876", "name": "", "equation": "UDP + H2O = UMP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XQY2-1", "A0A8V0ZNW3-1", "E1C1L6-1", "O93295-1", "P79784-1", "A0A1D5PS27-1", "A0A1D5PVS9-1", "A0A8V1AE46-1", "A0A8V1A8Y2-1" ], "evidence": [ { "id": "64876", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/64876" } ] }, { "id": "64880", "name": "", "equation": "CDP + H2O = CMP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XQY2-1", "A0A8V0ZNW3-1", "E1C1L6-1", "P79784-1" ], "evidence": [ { "id": "64880", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/64880" } ] }, { "id": "64896", "name": "", "equation": "UTP + 2 H2O = UMP + 2 phosphate + 2 H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZNW3-1", "O93295-1", "P79784-1", "A0A1D5PS27-1", "A0A1D5PVS9-1", "A0A8V1AE46-1", "A0A8V1A8Y2-1" ], "evidence": [ { "id": "64896", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/64896" } ] }, { "id": "64900", "name": "", "equation": "UTP + H2O = UDP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZNW3-1", "A0A8V0Z5P2-1", "A0A8V1ADZ7-1", "Q5ZM73-1", "Q5ZM83-1", "O93295-1", "P79784-1", "A0A1D5PS27-1", "A0A1D5PVS9-1", "A0A8V1AE46-1", "A0A8V1A8Y2-1" ], "evidence": [ { "id": "64900", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/64900" } ] }, { "id": "64904", "name": "", "equation": "GTP + 2 H2O = GMP + 2 phosphate + 2 H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZNW3-1", "P79784-1" ], "evidence": [ { "id": "64904", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/64904" } ] }, { "id": "64908", "name": "", "equation": "CTP + 2 H2O = CMP + 2 phosphate + 2 H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZNW3-1", "P79784-1" ], "evidence": [ { "id": "64908", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/64908" } ] }, { "id": "77735", "name": "", "equation": "ITP + 2 H2O = IMP + 2 phosphate + 2 H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZNW3-1", "P79784-1" ], "evidence": [ { "id": "77735", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/77735" } ] }, { "id": "R-GGA-8850846", "name": "NTPDase1 hydrolyzes nucleoside triphosphates", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "extracellular region, plasma membrane", "input_participant_list": [ "R-ALL-8870907" ], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZNW3-1" ], "evidence": [ { "id": "R-GGA-8850846", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8850846" } ] }, { "id": "R-GGA-8850854", "name": "NTPDase1 hydrolyzes nucleoside diphosphates", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "extracellular region, plasma membrane", "input_participant_list": [ "R-ALL-8870906" ], "output_participant_list": [ "R-ALL-8870962" ], "enzyme_list": [ "A0A8V0ZNW3-1" ], "evidence": [ { "id": "R-GGA-8850854", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8850854" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-8870906", "participant_name": "NDP [extracellular region]", "crossref": [ { "id": "57930", "database": "ChEBI", "url": "" } ] }, { "participant_id": "R-ALL-8870907", "participant_name": "NTP [extracellular region]", "crossref": [ { "id": "61557", "database": "ChEBI", "url": "" } ] }, { "participant_id": "R-ALL-8870962", "participant_name": "NMP [extracellular region]", "crossref": [ { "id": "58043", "database": "ChEBI", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5NTY5", "gene_name": "LOC430766", "activity": [ { "ec_number": "3.6.4.6", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5NTY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NTY5" } ] }, { "ec_number": "3.6.4.6", "activity": "", "evidence": [ { "id": "A0A1D5NTY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NTY5" } ] } ] }, { "uniprot_ac": "A0A1D5NV13", "gene_name": "RIT2", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5NV13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NV13" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A1D5NV13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NV13" } ] } ] }, { "uniprot_ac": "A0A1D5P1F5", "gene_name": "RAB40C", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5P1F5", "database": 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"id": "A0A1D5P5I0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P5I0" } ] } ] }, { "uniprot_ac": "A0A1D5PD32", "gene_name": "DDX17", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5PD32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PD32" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A1D5PD32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PD32" } ] } ] }, { "uniprot_ac": "A0A1D5PHB6", "gene_name": "DHX36", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5PHB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PHB6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A1D5PHB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PHB6" } ] } ] }, { "uniprot_ac": "A0A1D5PIN7", "gene_name": "DHX30", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5PIN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PIN7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A1D5PIN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PIN7" } ] } ] }, { "uniprot_ac": "A0A1D5PM27", "gene_name": "OPA1", "activity": [ { "ec_number": "3.6.5.5", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5PM27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PM27" } ] }, { "ec_number": "3.6.5.5", "activity": "", "evidence": [ { "id": "A0A1D5PM27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PM27" } ] } ] }, { "uniprot_ac": "A0A1D5PRR9", "gene_name": "FANCM", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5PRR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRR9" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A1D5PRR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRR9" } ] } ] }, { "uniprot_ac": "A0A1D5PS27", "gene_name": "ENTPD2", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "A0A1D5PS27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PS27" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "A0A1D5PS27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PS27" } ] } ] }, { "uniprot_ac": "A0A1D5PT95", "gene_name": "KRAS", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5PT95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PT95" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A1D5PT95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PT95" } ] } ] }, { "uniprot_ac": "A0A1D5PVS9", "gene_name": "ENTPD3", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "A0A1D5PVS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PVS9" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "A0A1D5PVS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PVS9" } ] } ] }, { "uniprot_ac": "A0A1L1RKZ0", "gene_name": "RASL11AL", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1L1RKZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RKZ0" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A1L1RKZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RKZ0" } ] } ] }, { "uniprot_ac": "A0A3Q2UG55", "gene_name": "RAB9B", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q2UG55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UG55" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A3Q2UG55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UG55" } ] } ] }, { "uniprot_ac": "A0A3Q2UHM4", "gene_name": "DNM1L", "activity": [ { "ec_number": "3.6.5.5", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q2UHM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UHM4" } ] }, { "ec_number": "3.6.5.5", "activity": "", "evidence": [ { "id": "A0A3Q2UHM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UHM4" } ] } ] }, { "uniprot_ac": "A0A3S5ZPN3", "gene_name": "DDX5", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3S5ZPN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPN3" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A3S5ZPN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPN3" } ] } ] }, { "uniprot_ac": "A0A8V0X600", "gene_name": "DDX43", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0X600", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X600" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0X600", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X600" } ] } ] }, { "uniprot_ac": "A0A8V0X655", "gene_name": "DHX32", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0X655", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X655" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0X655", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X655" } ] } ] }, { "uniprot_ac": "A0A8V0X962", "gene_name": "RAB31", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0X962", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X962" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0X962", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X962" } ] } ] }, { "uniprot_ac": "A0A8V0X9Y7", "gene_name": "CFTR", "activity": [ { "ec_number": "5.6.1.6", "activity": "ATP + H2O + closed Cl(-) channel = ADP + phosphate + open Cl(-) channel.", "evidence": [ { "id": "A0A8V0X9Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X9Y7" } ] }, { "ec_number": "5.6.1.6", "activity": "", "evidence": [ { "id": "A0A8V0X9Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X9Y7" } ] } ] }, { "uniprot_ac": "A0A8V0X9Z6", "gene_name": "MOV10L1", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0X9Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X9Z6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0X9Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X9Z6" } ] } ] }, { "uniprot_ac": "A0A8V0XBX5", "gene_name": "RAP2B", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XBX5", "database": "UniProtKB", "url": 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"database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XDD5" } ] } ] }, { "uniprot_ac": "A0A8V0XEC4", "gene_name": "DDX10", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XEC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEC4" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0XEC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEC4" } ] } ] }, { "uniprot_ac": "A0A8V0XG98", "gene_name": "HELQ", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XG98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XG98" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A8V0XG98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XG98" } ] } ] }, { "uniprot_ac": "A0A8V0XGK7", "gene_name": "RAB6A", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XGK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XGK7" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0XGK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XGK7" } ] } ] }, { "uniprot_ac": "A0A8V0XGV3", "gene_name": "DDX3X", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XGV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XGV3" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0XGV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XGV3" } ] } ] }, { "uniprot_ac": "A0A8V0XHD1", "gene_name": "AQR", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": 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"activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XLC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLC7" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0A8V0XLC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLC7" } ] } ] }, { "uniprot_ac": "A0A8V0XMC5", "gene_name": "RAB10L", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XMC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMC5" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0XMC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMC5" } ] } ] }, { "uniprot_ac": "A0A8V0XMP8", "gene_name": "ZGRF1", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication 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{ "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YCY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY8" } ] } ] }, { "uniprot_ac": "A0A8V0YDI7", "gene_name": "RAB17", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YDI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDI7" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0YDI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDI7" } ] } ] }, { "uniprot_ac": "A0A8V0YDX6", "gene_name": "", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YDX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDX6" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0YDX6", "database": "UniProtKB", "url": 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"activity": "", "evidence": [ { "id": "A0A8V0YIU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIU8" } ] } ] }, { "uniprot_ac": "A0A8V0YLC1", "gene_name": "DDX11", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "A0A8V0YLC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLC1" } ] }, { "ec_number": "5.6.2.3", "activity": "", "evidence": [ { "id": "A0A8V0YLC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLC1" } ] } ] }, { "uniprot_ac": "A0A8V0YLM0", "gene_name": "RECQL", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YLM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLM0" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": 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} ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V1AIF5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIF5" } ] } ] }, { "uniprot_ac": "A0A8V1AIK2", "gene_name": "DDX25", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1AIK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIK2" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V1AIK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIK2" } ] } ] }, { "uniprot_ac": "A0A8V1AJ43", "gene_name": "DHX40", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1AJ43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ43" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V1AJ43", "database": "UniProtKB", "url": 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[E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1ALH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALH0" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1ALH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALH0" } ] } ] }, { "uniprot_ac": "A0A8V1AMW1", "gene_name": "CANT1", "activity": [ { "ec_number": "3.6.1.6", "activity": "a ribonucleoside 5'-diphosphate + H2O = a ribonucleoside 5'-phosphate + phosphate + H(+).", "evidence": [ { "id": "A0A8V1AMW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMW1" } ] }, { "ec_number": "3.6.1.6", "activity": "", "evidence": [ { "id": "A0A8V1AMW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMW1" } ] } ] }, { "uniprot_ac": "A0A8V1AN75", "gene_name": "RAB37", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1AN75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN75" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V1AN75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN75" } ] } ] }, { "uniprot_ac": "A0A8V1AP30", "gene_name": "RAB40B", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1AP30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP30" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V1AP30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP30" } ] } ] }, { "uniprot_ac": "A0A8V1API8", "gene_name": "RASL10B", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1API8", "database": "UniProtKB", "url": 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"id": "E1BWN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWN3" } ] } ] }, { "uniprot_ac": "E1BY42", "gene_name": "IGHMBP2", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BY42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY42" } ] }, { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BY42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY42" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1BY42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY42" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "E1BY42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY42" } ] } ] }, { "uniprot_ac": "E1C1L6", "gene_name": "ENTPD5", "activity": [ { "ec_number": "3.6.1.6", "activity": "a ribonucleoside 5'-diphosphate + H2O = a ribonucleoside 5'-phosphate + phosphate + H(+).", "evidence": [ { "id": "E1C1L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C1L6" } ] }, { "ec_number": "3.6.1.6", "activity": "", "evidence": [ { "id": "E1C1L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C1L6" } ] } ] }, { "uniprot_ac": "F1N8Z4", "gene_name": "RUVBL1", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1N8Z4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N8Z4" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "F1N8Z4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N8Z4" } ] } ] }, { "uniprot_ac": "F1N991", "gene_name": "DDX4", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1N991", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N991" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1N991", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N991" } ] } ] }, { "uniprot_ac": "F1NA92", "gene_name": "CLPX", "activity": [ { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1NA92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NA92" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "F1NA92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NA92" } ] } ] }, { "uniprot_ac": "F1ND48", "gene_name": "FBH1", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1ND48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1ND48" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "F1ND48", "database": "UniProtKB", "url": 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"activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "F1NSA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NSA8" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "F1NSA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NSA8" } ] } ] }, { "uniprot_ac": "F1NTD6", "gene_name": "ascc3", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1NTD6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NTD6" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "F1NTD6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NTD6" } ] } ] }, { "uniprot_ac": "F1NWF1", "gene_name": "RAB30", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "F1NWF1", "database": "UniProtKB", "url": 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"publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "P27731-1", "uniprot_ac": "P27731", "uniprot_id": "TTHY_CHICK", "mass": { "chemical_mass": 16309.0, "monoisotopic_mass": 16309.0 }, "refseq": { "ac": "NP_990666", "name": "transthyretin isoform 1 precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990666" }, "gene_names": [ { "name": "TTR", "type": "recommended", "evidence": [ { "id": "P27731", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P27731" } ] }, { "name": "TTR", "type": "synonym", "evidence": [ { "id": "NP_990666", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990666" } ] } ], "protein_names": [ { "name": "Transthyretin", "type": "recommended", "evidence": [ { "id": "P27731", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P27731/entry#names_and_taxonomy" } ] }, { "name": "Prealbumin", "type": "synonym", "evidence": [ { "id": "P27731", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P27731/entry#names_and_taxonomy" } ] }, { "name": "TBPA", "type": "synonym", "evidence": [ { "id": "NP_990666", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990666" }, { "id": "P27731", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P27731/entry#names_and_taxonomy" } ] }, { "name": "prealbumin", "type": "synonym", "evidence": [ { "id": "NP_990666", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990666" } ] }, { "name": "transthyretin isoform 1 precursor", "type": "synonym", "evidence": [ { "id": "NP_990666", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990666" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: BU269372.1, BU264821.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BU269372.1, X60471.1, DN851840.1, BU339400.1 and BU352734.1. Transcript Variant: This variant (1) represents the shorter transcript and encodes the shorter protein (isoform 1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.", "evidence": [ { "database": "RefSeq", "id": "NP_990666", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990666" } ] }, { "annotation": "Difference in triiodophenol(TIP) binding between female and male chickens; females bind less TIP than male adult and juvenile chickens.", "evidence": [ { "database": "RefSeq", "id": "NP_990666", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990666" }, { "database": "PubMed", "id": "21147258", "url": "https://glygen.org/publication/PubMed/21147258" } ] }, { "annotation": "Significant amount of diethylstilbestrol and ioxynil interacted with TTR in whole chicken serum.", "evidence": [ { "database": "RefSeq", "id": "NP_990666", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990666" }, { "database": "PubMed", "id": "18243807", "url": "https://glygen.org/publication/PubMed/18243807" } ] }, { "annotation": "TTR, Deiodinase 3 and OATP1C1 expression were found to be highly concentrated in the choroid plexus.", "evidence": [ { "database": "RefSeq", "id": "NP_990666", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990666" }, { "database": "PubMed", "id": "28919452", "url": "https://glygen.org/publication/PubMed/28919452" } ] }, { "annotation": "Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0XRG8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XRG8#function" }, { "database": "UniProtKB", "id": "RU361269", "url": "https://www.uniprot.org/uniprotkb/RU361269#function" }, { "database": "UniProtKB", "id": "A0A1I7Q422", "url": "https://www.uniprot.org/uniprotkb/A0A1I7Q422#function" }, { "database": "UniProtKB", "id": "P27731", "url": "https://www.uniprot.org/uniprotkb/P27731#function" }, { "database": "PubMed", "id": "1833190", "url": "https://glygen.org/publication/PubMed/1833190" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "P27731", "url": "https://www.uniprot.org/uniprotkb/P27731" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TTR", "url": "https://www.uniprot.org/uniprotkb/P27731", "locus": { "chromosome": "2", "start_pos": 105800065, "end_pos": 105791008, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010006069", "url": "https://www.ensembl.org/id/ENSGALG00010006069" } ] } } ], "crossref": [ { "id": "P27731", "url": "https://alphafold.ebi.ac.uk/entry/P27731", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000015143", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000015143", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd05821", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05821", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "396277", "url": "https://www.ncbi.nlm.nih.gov/gene/396277", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "1TFP", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=1TFP&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "P27731", "url": "https://www.ebi.ac.uk/intact/interactors/id:P27731*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "IPR000895", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000895", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023416", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023416", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023418", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023418", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023419", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023419", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036817", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036817", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:396277", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:396277", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "AMYKVEL", "url": "https://omabrowser.org/oma/group/AMYKVEL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1I7Q422", "url": "https://www.orthodb.org/?gene=A0A1I7Q422", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XRG8", "url": "https://www.orthodb.org/?gene=A0A8V0XRG8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "P27731", "url": "https://www.orthodb.org/?gene=P27731", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10395", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10395", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10395:SF12", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10395:SF12", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "pdb_00001tfp", "url": "https://www.rcsb.org/structure/pdb_00001tfp", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "1TFP", "url": "https://www.rcsb.org/structure/1TFP", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "PF00576", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00576", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:P27731", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:P27731", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_990666", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990666", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1I7Q422", "url": "https://www.uniprot.org/uniprotkb/A0A1I7Q422", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1I7Q422-1", "url": "https://www.uniprot.org/uniprotkb/A0A1I7Q422-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XRG8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XRG8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XRG8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XRG8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P27731", "url": "https://www.uniprot.org/uniprotkb/P27731", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P27731-1", "url": "https://www.uniprot.org/uniprotkb/P27731-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAFHSTLLVFLAGLVFLSEAAPLVSHGSVDSKCPLMVKVLDAVRGSPAANVAVKVFKKAADGTWQDFATGKTTEFGEIHELTTEEQFVEGVYRVEFDTSSYWKGLGLSPFHEYADVVFTANDSGHRHYTIAALLSPFSYSTTAVVSDPQE", "length": 150, "header": "sp|P27731-1|TTHY_CHICK Isoform 1 of Transthyretin OS=Gallus gallus OX=9031 GN=TTR PE=1 SV=1 CANONICAL=P27731-1" }, "isoforms": [ { "isoform_ac": "A0A1I7Q422-1", "url": "https://www.uniprot.org/uniprotkb/P27731/entry#A0A1I7Q422-1", "sequence": { "sequence": "MICYCWSPCTNFYAWKLNIECYLPLSLLCSGLVFLSEAAPLVSHGSVDSKCPLMVKVLDAVRGSPAANVAVKVFKKAADGTWQDFATGKTTEFGEIHELTTEEQFVEGVYRVEFDTSSYWKGLGLSPFHEYADVVFTANDSGHRHYTIAALLSPFSYSTTAVVSDPQE", "length": 168, "header": "tr|A0A1I7Q422-1|TTHY_CHICK Computationally mapped isoform of Transthyretin OS=Gallus gallus OX=9031 GN=TTR PE=1 SV=1 CANONICAL=P27731-1" }, "locus": { "chromosome": "2", "start_pos": 105799865, "end_pos": 105791040, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010014520.1", "url": "https://www.ensembl.org/id/ENSGALT00010014520.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010008537.1", "url": "https://www.ensembl.org/id/ENSGALP00010008537.1" } ] } }, { "isoform_ac": "A0A8V0XRG8-1", "url": "https://www.uniprot.org/uniprotkb/P27731/entry#A0A8V0XRG8-1", "sequence": { "sequence": "MAFHSTLLVFLAGLVFLSEAAPLVSHGSVDSKCPLMVKVLDAVRGSPAANVAADGTWQDFATGKTTEFGEIHELTTEEQFVEGVYRVEFDTSSYWKGLGLSPFHEYADVVFTANDSGHRHYTIAALLSPFSYSTTAVVSDPQE", "length": 143, "header": "tr|A0A8V0XRG8-1|TTHY_CHICK Computationally mapped isoform of Transthyretin OS=Gallus gallus OX=9031 GN=TTR PE=1 SV=1 CANONICAL=P27731-1" }, "locus": { "chromosome": "2", "start_pos": 105799865, "end_pos": 105792426, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010014517.1", "url": "https://www.ensembl.org/id/ENSGALT00010014517.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010008534.1", "url": "https://www.ensembl.org/id/ENSGALP00010008534.1" } ] } }, { "isoform_ac": "P27731-1", "url": "https://www.uniprot.org/uniprotkb/P27731/entry#P27731-1", "sequence": { "sequence": "MAFHSTLLVFLAGLVFLSEAAPLVSHGSVDSKCPLMVKVLDAVRGSPAANVAVKVFKKAADGTWQDFATGKTTEFGEIHELTTEEQFVEGVYRVEFDTSSYWKGLGLSPFHEYADVVFTANDSGHRHYTIAALLSPFSYSTTAVVSDPQE", "length": 150, "header": "sp|P27731-1|TTHY_CHICK Isoform 1 of Transthyretin OS=Gallus gallus OX=9031 GN=TTR PE=1 SV=1 CANONICAL=P27731-1" }, "locus": { "chromosome": "2", "start_pos": 105799865, "end_pos": 105792426, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010014515.1", "url": "https://www.ensembl.org/id/ENSGALT00010014515.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010008532.1", "url": "https://www.ensembl.org/id/ENSGALP00010008532.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Ontogenesis of transthyretin gene expression in chicken choroid plexus and liver.", "journal": "Comp. Biochem. Physiol.", "date": "1991", "authors": "Southwell B R, Duan W, Tu G F, Schreiber G", "evidence": [ { "database": "UniProtKB", "id": "P27731", "url": "https://www.uniprot.org/uniprotkb/P27731" } ], "reference": [ { "type": "PubMed", "id": "1799976", "url": "https://glygen.org/publication/PubMed/1799976" } ] }, { "title": "Interaction of diethylstilbestrol and ioxynil with transthyretin in chicken serum.", "journal": "Comparative biochemistry and physiology. Toxicology & pharmacology : CBP", "date": "2008-04", "authors": "Eguchi Ryoji, Ishihara Akinori, Yamauchi Kiyoshi", "evidence": [ { "database": "RefSeq", "id": "NP_990666", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990666" } ], "reference": [ { "type": "PubMed", "id": "18243807", "url": "https://glygen.org/publication/PubMed/18243807" } ] }, { "title": "Isolation, characterization, cDNA cloning and gene expression of an avian transthyretin. Implications for the evolution of structure and function of transthyretin in vertebrates.", "journal": "European journal of biochemistry", "date": "1991-09-15", "authors": "Duan W, Achen M G, Richardson S J, Lawrence M C, Wettenhall R E, Jaworowski A, Schreiber G", "evidence": [ { "database": "UniProtKB", "id": "P27731", "url": "https://www.uniprot.org/uniprotkb/P27731" } ], "reference": [ { "type": "PubMed", "id": "1833190", "url": "https://glygen.org/publication/PubMed/1833190" } ] }, { "title": "Characterization of plasma triiodophenol binding proteins in vertebrates and tissue distribution of triiodophenol in Rana catesbeiana tadpoles.", "journal": "Comparative biochemistry and physiology. Toxicology & pharmacology : CBP", "date": "2011-04", "authors": "Yamauchi Kiyoshi, Sai Gobun", "evidence": [ { "database": "RefSeq", "id": "NP_990666", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990666" } ], "reference": [ { "type": "PubMed", "id": "21147258", "url": "https://glygen.org/publication/PubMed/21147258" } ] }, { "title": "The affinity of transthyretin for T3 or T4 does not determine which form of the hormone accumulates in the choroid plexus.", "journal": "General and comparative endocrinology", "date": "2018-08-01", "authors": "Richardson Samantha J, Van Herck Stijn, Delbaere Joke, McAllan Bronwyn M, Darras Veerle M", "evidence": [ { "database": "RefSeq", "id": "NP_990666", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990666" } ], "reference": [ { "type": "PubMed", "id": "28919452", "url": "https://glygen.org/publication/PubMed/28919452" } ] }, { "title": "The crystal structure of transthyretin from chicken.", "journal": "Eur. J. Biochem.", "date": "1996", "authors": "Sunde M, Richardson S J, Chang L, Pettersson T M, Schreiber G, Blake C C", "evidence": [ { "database": "UniProtKB", "id": "P27731", "url": "https://www.uniprot.org/uniprotkb/P27731" } ], "reference": [ { "type": "PubMed", "id": "8612621", "url": "https://glygen.org/publication/PubMed/8612621" } ] } ], "pathway": [ { "id": "gga:396277", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:396277", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "B8JLL8-1", "protein_name": "Transthyretin", "gene_name": "ttr", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAKEVICVLLASLFALCRSAPVAFHGGSDAHCPLTVKILDAVKGTPAGNIALDLFRQDQGGTWEKIASGKVDMTGEVHNLITEQEFTPGVYRVEFDTLTYWKTEGRTPFHQLADVVFEAHAEGHRHYTLALLLSPFSYTTTAVVVKAHD", "length": 149 }, "evidence": [ { "id": "P27731", "url": "https://omabrowser.org/oma/group/P27731/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "G3I4M9-1", "protein_name": "Transthyretin", "gene_name": "Ttr", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MASPHLFLLCLAGLAFMSEAGPSGTGESRCPLMVKVLDAVRGSPAVDVAVQVFKKTAQGTWEPFASGKTAESGELHGLTTDEKFVEGVYRVELDTKSYWKALGISPFHEYAEVVFTANDSGHRHYTIAALLSPYSYSTTAVVSNPKV", "length": 147 }, "evidence": [ { "id": "P27731", "url": "https://omabrowser.org/oma/group/P27731/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "O46375-1", "protein_name": "Transthyretin", "gene_name": "TTR", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MASFRLFLLCLAGLVFVSEAGSVGAGEPKCPLMVKVLDAVRGSPAANVGVKVFKKAADETWEPFASGKTSESGELHGLTTEDKFVEGLYKVELDTKSYWKSLGISPFHEFAEVVFTANDSGPRHYTIAALLSPYSYSTTALVSSPKA", "length": 147 }, "evidence": [ { "id": "P27731", "url": "https://omabrowser.org/oma/group/P27731/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P02766-1", "protein_name": "Transthyretin", "gene_name": "TTR", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASHRLLLLCLAGLVFVSEAGPTGTGESKCPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYSTTAVVTNPKE", "length": 147 }, "evidence": [ { "id": "P27731", "url": "https://omabrowser.org/oma/group/P27731/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P02767-1", "protein_name": "Transthyretin", "gene_name": "Ttr", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASLRLFLLCLAGLIFASEAGPGGAGESKCPLMVKVLDAVRGSPAVDVAVKVFKKTADGSWEPFASGKTAESGELHGLTTDEKFTEGVYRVELDTKSYWKALGISPFHEYAEVVFTANDSGHRHYTIAALLSPYSYSTTAVVSNPQN", "length": 147 }, "evidence": [ { "id": "P27731", "url": "https://omabrowser.org/oma/group/P27731/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P07309-1", "protein_name": "Transthyretin", "gene_name": "Ttr", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASLRLFLLCLAGLVFVSEAGPAGAGESKCPLMVKVLDAVRGSPAVDVAVKVFKKTSEGSWEPFASGKTAESGELHGLTTDEKFVEGVYRVELDTKSYWKTLGISPFHEFADVVFTANDSGHRHYTIAALLSPYSYSTTAVVSNPQN", "length": 147 }, "evidence": [ { "id": "P27731", "url": "https://omabrowser.org/oma/group/P27731/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P50390-1", "protein_name": "Transthyretin", "gene_name": "TTR", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MASYRLLLLCLAGLVFVSEAGPAGAGESKCPLMVKVLDAVRGSPAVNVGVKVFKKAADGTWEPFALGKTSEFGELHGLTTDEKFVEGIYKVELDTKSYWKALGISPFHEYAEVVFTANDSGRRHYTIAALLSPYSYSTTALVSSPKEGAL", "length": 150 }, "evidence": [ { "id": "P27731", "url": "https://omabrowser.org/oma/group/P27731/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "P27731", "url": "https://www.uniprot.org/uniprotkb/P27731" } ], "pmid": "" }, { "name": "clathrin-coated vesicle", "id": "GO:0030136", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030136", "evidence": [ { "database": "UniProtKB", "id": "P27731", "url": "https://www.uniprot.org/uniprotkb/P27731" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "P27731", "url": "https://www.uniprot.org/uniprotkb/P27731" } ], "pmid": "" }, { "name": "yolk", "id": "GO:0060417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060417", "evidence": [ { "database": "UniProtKB", "id": "P27731", "url": "https://www.uniprot.org/uniprotkb/P27731" } ], "pmid": "" }, { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "P27731", "url": "https://www.uniprot.org/uniprotkb/P27731" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "protein domain specific binding", "id": "GO:0019904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019904", "evidence": [ { "database": "UniProtKB", "id": "P27731", "url": "https://www.uniprot.org/uniprotkb/P27731" } ], "pmid": "" }, { "name": "protein heterodimerization activity", "id": "GO:0046982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046982", "evidence": [ { "database": "UniProtKB", "id": "P27731", "url": "https://www.uniprot.org/uniprotkb/P27731" } ], "pmid": "" }, { "name": "hormone binding", "id": "GO:0042562", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042562", "evidence": [ { "database": "UniProtKB", "id": "P27731", "url": "https://www.uniprot.org/uniprotkb/P27731" } ], "pmid": "" }, { "name": "thyroid hormone binding", "id": "GO:0070324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070324", "evidence": [ { "database": "UniProtKB", "id": "P27731", "url": "https://www.uniprot.org/uniprotkb/P27731" } ], "pmid": "" }, { "name": "hormone activity", "id": "GO:0005179", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005179", "evidence": [ { "database": "UniProtKB", "id": "P27731", "url": "https://www.uniprot.org/uniprotkb/P27731" } ], "pmid": "" }, { "name": "small molecule binding", "id": "GO:0036094", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036094", "evidence": [ { "database": "UniProtKB", "id": "P27731", "url": "https://www.uniprot.org/uniprotkb/P27731" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "protein tetramerization", "id": "GO:0051262", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051262", "evidence": [ { "database": "UniProtKB", "id": "P27731", "url": "https://www.uniprot.org/uniprotkb/P27731" } ], "pmid": "" }, { "name": "retinol metabolic process", "id": "GO:0042572", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042572", "evidence": [ { "database": "UniProtKB", "id": "P27731", "url": "https://www.uniprot.org/uniprotkb/P27731" } ], "pmid": "" }, { "name": "response to virus", "id": "GO:0009615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009615", "evidence": [ { "database": "UniProtKB", "id": "P27731", "url": "https://www.uniprot.org/uniprotkb/P27731" } ], "pmid": "" }, { "name": "thyroid hormone transport", "id": "GO:0070327", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070327", "evidence": [ { "database": "UniProtKB", "id": "P27731", "url": "https://www.uniprot.org/uniprotkb/P27731" } ], "pmid": "" }, { "name": "oocyte growth", "id": "GO:0001555", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001555", "evidence": [ { "database": "UniProtKB", "id": "P27731", "url": "https://www.uniprot.org/uniprotkb/P27731" } ], "pmid": "" }, { "name": "protein-containing complex assembly", "id": "GO:0065003", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0065003", "evidence": [ { "database": "UniProtKB", "id": "P27731", "url": "https://www.uniprot.org/uniprotkb/P27731" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 121, "end_pos": 123, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-P27731-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 150, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-P27731-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/P27731" }, { "pdb_id": "1tfp", "pdb_chain": "a/b", "start_pos": 21, "end_pos": 150, "overlap": "1.0", "method": "X-Ray_Crystallography", "type": "experimental", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/1tfp.pdb", "url_external": "https://www.rcsb.org/structure/1tfp" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 121, "end_pos": 123 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ 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"ATPase, Ca++ transporting, cardiac muscle, slow twitch 2", "type": "synonym", "evidence": [ { "id": "NP_001258903", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001258903" } ] }, { "name": "SR Ca(2+)-ATPase 2", "type": "synonym", "evidence": [ { "id": "NP_001258903", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001258903" } ] }, { "name": "calcium pump 2", "type": "synonym", "evidence": [ { "id": "NP_001258903", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001258903" } ] }, { "name": "endoplasmic reticulum class 1/2 Ca(2+) ATPase", "type": "synonym", "evidence": [ { "id": "NP_001258903", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001258903" } ] }, { "name": "sarcoplasmic/endoplasmic reticulum calcium ATPase 2 isoform 2", "type": "synonym", "evidence": [ { "id": "NP_001258903", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001258903" } ] }, { "name": "sarcoplasmic/endoplasmic reticulum calcium ATPase 2", "type": "synonym", "evidence": [ { "id": "NP_001258903", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001258903" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR13267655.251676.1, SRR13267658.12997.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000260.1. Sequence Note:.", "evidence": [ { "database": "RefSeq", "id": "NP_001258903", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001258903" } ] }, { "annotation": "Catalyzes the hydrolysis of ATP coupled with the transport of calcium.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A667", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A667#function" }, { "database": "UniProtKB", "id": "RU361146", "url": "https://www.uniprot.org/uniprotkb/RU361146#function" }, { "database": "UniProtKB", "id": "A0A1L1RKB7", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RKB7#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RKB7", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RKB7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ATP2A2", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RKB7", "locus": { "chromosome": "15", "start_pos": 5319274, "end_pos": 5360262, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010025130", "url": "https://www.ensembl.org/id/ENSGALG00010025130" } ] } } ], "crossref": [ { "id": "A0A1L1RKB7", "url": "https://alphafold.ebi.ac.uk/entry/A0A1L1RKB7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000032287", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000032287", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd02083", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02083", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "396446", "url": "https://www.ncbi.nlm.nih.gov/gene/396446", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001757", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001757", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004014", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004014", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005782", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005782", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006068", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006068", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008250", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008250", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018303", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018303", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023214", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023214", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023298", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023298", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023299", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023299", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036412", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036412", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044492", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044492", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR059000", "url": "https://www.ebi.ac.uk/interpro/entry/IPR059000", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:396446", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:396446", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PLWNNMM", "url": "https://omabrowser.org/oma/group/PLWNNMM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1L1RKB7", "url": "https://www.orthodb.org/?gene=A0A1L1RKB7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A667", "url": "https://www.orthodb.org/?gene=A0A8V1A667", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR42861", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR42861", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00122", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00122", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00689", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00689", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00690", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00690", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08282", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08282", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13246", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13246", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-418359", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-418359", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5578775", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5578775", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-936837", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-936837", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001258903", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001258903", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "18105", "url": "https://www.rhea-db.org/rhea/18105", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A1L1RKB7", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RKB7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1L1RKB7-1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RKB7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A667", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A667", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A667-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A667-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": 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"length": 1042, "header": "tr|A0A1L1RKB7-1|A0A1L1RKB7_CHICK Isoform 1 of Calcium-transporting ATPase OS=Gallus gallus OX=9031 GN=ATP2A2 PE=3 SV=2 CANONICAL=A0A1L1RKB7-1" }, "isoforms": [ { "isoform_ac": "A0A1L1RKB7-1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RKB7/entry#A0A1L1RKB7-1", "sequence": { "sequence": "MENAHTKTVEEVLAYFGVNESTGLSLEQVKKLKEKWGSNELPAEEGKTLLELVIEQFEDLLVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEALKEYEPEMGKVYRQDRKSVQRIKARDIVPGDIVEVAVGDKVPADIRITSIKSTTLRVDQSILTGESVSVIKHTDPVPDPRAVNQDKKNMLFSGTNIAAGKAMGVVIATGVNTEIGKIRDEMVATEQERTPLQQKLDEFGEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAVALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCRMFILDKVEGDSCSLNEFTVTGSTYAPMGEVHKDDKLIKCSQYDGLVELATICALCNDSSLDYNEAKGVYEKVGEATETALTCLVEKMNVFDTDLKGLSRIERANACNSVIKQLMKKEFTLEFSRDRKSMSVYCTPNKPSRTSMSKMFVKGAPEGVIDRCTHVRVGNAKIPLSSGIKQKIMSVIREWGTGRDTLRCLALATHDNPPRKEEMNLEDSSNFINYETNLTFVGCVGMLDPPRIEVASSIKLCKQAGIRVIMITGDNKGTAVAICRRIGIFVEDEDVSTKAFTGREFDELSLAAQRDACHHARCFARVEPSHKSKIVEFLQSFDEITAMTGDGVNDAPALKKAEIGIAMGSGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAALGFPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMNKPPRNPKEPLISGWLFFRYLAIGCYVGAATVGAAAWWFIAADGGPRVTFYQLSHFLQCKEDNPDFSGVDCVVFESPYPMTMALSVLVTIEMCNALNSLSENQSLMRMPPWENIWLVGAICLSMSLHFLILYVEPLPIIFQITPLNVTQWLMVLKISLPVILLDETLKYVARNYLEPGKDSVQPATKPCSLSACTEGVSWPFVFITLPLVIWLYSTDTNFSDMFWS", "length": 1042, "header": "tr|A0A1L1RKB7-1|A0A1L1RKB7_CHICK Isoform 1 of Calcium-transporting ATPase OS=Gallus gallus OX=9031 GN=ATP2A2 PE=3 SV=2 CANONICAL=A0A1L1RKB7-1" }, "locus": { "chromosome": "15", "start_pos": 5360041, "end_pos": 5325152, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010061313.1", "url": "https://www.ensembl.org/id/ENSGALT00010061313.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010037911.1", "url": "https://www.ensembl.org/id/ENSGALP00010037911.1" } ] } }, { "isoform_ac": "A0A8V1A667-1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RKB7/entry#A0A8V1A667-1", "sequence": { "sequence": "MENAHTKTVEEVLAYFGVNESTGLSLEQVKKLKEKWGSNELPAEEGKTLLELVIEQFEDLLVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEALKEYEPEMGKVYRQDRKSVQRIKARDIVPGDIVEVAVGDKVPADIRITSIKSTTLRVDQSILTGESVSVIKHTDPVPDPRAVNQDKKNMLFSGTNIAAGKAMGVVIATGVNTEIGKIRDEMVATEQERTPLQQKLDEFGEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAVALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCRMFILDKVEGDSCSLNEFTVTGSTYAPMGEVHKDDKLIKCSQYDGLVELATICALCNDSSLDYNEAKGVYEKVGEATETALTCLVEKMNVFDTDLKGLSRIERANACNSVIKQLMKKEFTLEFSRDRKSMSVYCTPNKPSRTSMSKMFVKGAPEGVIDRCTHVRVGNAKIPLSSGIKQKIMSVIREWGTGRDTLRCLALATHDNPPRKEEMNLEDSSNFINYETNLTFVGCVGMLDPPRIEVASSIKLCKQAGIRVIMITGDNKGTAVAICRRIGIFVEDEDVSTKAFTGREFDELSLAAQRDACHHARCFARVEPSHKSKIVEFLQSFDEITAMTGDGVNDAPALKKAEIGIAMGSGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAALGFPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMNKPPRNPKEPLISGWLFFRYLAIGCYVGAATVGAAAWWFIAADGGPRVTFYQLSHFLQCKEDNPDFSGVDCVVFESPYPMTMALSVLVTIEMCNALNRFVSPDQVGGFCIAYLKSYLLRSPALSLWTAQLINNESYFLSDSW", "length": 958, "header": "tr|A0A8V1A667-1|A0A1L1RKB7_CHICK Computationally mapped isoform of Calcium-transporting ATPase OS=Gallus gallus OX=9031 GN=ATP2A2 PE=3 SV=1 CANONICAL=A0A1L1RKB7-1" }, "locus": { "chromosome": "15", "start_pos": 5360041, "end_pos": 5326422, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010061309.1", "url": "https://www.ensembl.org/id/ENSGALT00010061309.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010037908.1", "url": "https://www.ensembl.org/id/ENSGALP00010037908.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:396446", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:396446", "resource": "KEGG Pathway" }, { "id": "R-GGA-418359", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-418359", "resource": "Reactome", "description": "Reduction of cytosolic Ca++ levels" }, { "id": "R-GGA-5578775", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5578775", "resource": "Reactome", "description": "Ion homeostasis" }, { "id": "R-GGA-936837", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-936837", "resource": "Reactome", "description": "Ion transport by P-type ATPases" } ], "orthologs": [ { "uniprot_canonical_ac": "O55143-1", "protein_name": "Sarcoplasmic/endoplasmic reticulum calcium ATPase 2", "gene_name": "Atp2a2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MENAHTKTVEEVLGHFGVNESTGLSLEQVKKLKERWGSNELPAEEGKTLLELVIEQFEDLLVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEALKEYEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIAVGDKVPADIRLTSIKSTTLRVDQSILTGESVSVIKHTDPVPDPRAVNQDKKNMLFSGTNIAAGKAMGVVVATGVNTEIGKIRDEMVATEQERTPLQQKLDEFGEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAVALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCRMFILDKVEGDTCSLNEFSITGSTYAPIGEVQKDDKPVKCHQYDGLVELATICALCNDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTELKGLSKIERANACNSVIKQLMKKEFTLEFSRDRKSMSVYCTPNKPSRTSMSKMFVKGAPEGVIDRCTHIRVGSTKVPMTPGVKQKIMSVIREWGSGSDTLRCLALATHDNPLKREEMHLEDSANFIKYETNLTFVGCVGMLDPPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQDEDVTSKAFTGREFDELSPSAQRDACLNARCFARVEPSHKSKIVEFLQSFDEITAMTGDGVNDAPALKKSEIGIAMGSGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAALGFPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMNKPPRNPKEPLISGWLFFRYLAIGCYVGAATVGAAAWWFIAADGGPRVSFYQLSHFLQCKEDNPDFDGVDCAIFESPYPMTMALSVLVTIEMCNALNSLSENQSLLRMPPWENIWLVGSICLSMSLHFLILYVEPLPLIFQITPLNLTQWLMVLKISLPVILMDETLKFVARNYLEQPGKECVQPATKSSCSLSACTDGISWPFVLLIMPLVVWVYSTDTNFSDMFWS", "length": 1044 }, "evidence": [ { "id": "A0A1L1RKB7", "url": "https://omabrowser.org/oma/group/A0A1L1RKB7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P11507-1", "protein_name": "Sarcoplasmic/endoplasmic reticulum calcium ATPase 2", "gene_name": "Atp2a2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MENAHTKTVEEVLGHFGVNESTGLSLEQVKKLKERWGSNELPAEEGKTLLELVIEQFEDLLVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEALKEYEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIAVGDKVPADIRLTSIKSTTLRVDQSILTGESVSVIKHTDPVPDPRAVNQDKKNMLFSGTNIAAGKAMGVVVATGVNTEIGKIRDEMVATEQERTPLQQKLDEFGEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAVALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCRMFILDKVEGDTCSLNEFTITGSTYAPIGEVQKDDKPVKCHQYDGLVELATICALCNDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTELKGLSKIERANACNSVIKQLMKKEFTLEFSRDRKSMSVYCTPNKPSRTSMSKMFVKGAPEGVIDRCTHIRVGSTKVPMTPGVKQKIMSVIREWGSGSDTLRCLALATHDNPLRREEMHLEDSANFIKYETNLTFVGCVGMLDPPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQDEDVTSKAFTGREFDELSPSAQRDACLNARCFARVEPSHKSKIVEFLQSFDEITAMTGDGVNDAPALKKSEIGIAMGSGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAALGFPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMNKPPRNPKEPLISGWLFFRYLAIGCYVGAATVGAAAWWFIAADGGPRVSFYQLSHFLQCKEDNPDFEGVDCAIFESPYPMTMALSVLVTIEMCNALNSLSENQSLLRMPPWENIWLVGSICLSMSLHFLILYVEPLPLIFQITPLNLTQWLMVLKISLPVILMDETLKFVARNYLEPGKECAQPATKPSCSLSACTDGISWPFVLLIMPLVVWVYSTDTNFSDMFWS", "length": 1043 }, "evidence": [ { "id": "A0A1L1RKB7", "url": "https://omabrowser.org/oma/group/A0A1L1RKB7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P11607-1", "protein_name": "Sarcoplasmic/endoplasmic reticulum calcium ATPase 2", "gene_name": "ATP2A2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MENAHTKTVEEVLGHFGVNESTGLSLEQVKKLKERWGSNELPAEEGKTLLELVIEQFEDLLVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEALKEYEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIAVGDKVPADIRLTSIKSTTLRVDQSILTGESVSVIKHTDPVPDPRAVNQDKKNMLFSGTNIAAGKAMGVVVATGVNTEIGKIRDEMVATEQERTPLQQKLDEFGEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAVALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCRMFILDKVEGDTCSLNEFTITGSTYAPIGEVHKDDKPVKCHQYDGLVELATICALCNDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTELKGLSKIERANACNSVIKQLMKKEFTLEFSRDRKSMSVYCTPNKPSRTSMSKMFVKGAPEGVIDRCTHIRVGSTKVPMTPGVKQKIMSVIREWGSGSDTLRCLALATHDNPMRREEMNLEDSANFIKYETNLTFVGCVGMLDPPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQDEDVTSKAFTGREFDELNPSAQREACLNARCFARVEPSHKSKIVEFLQSFDEITAMTGDGVNDAPALKKSEIGIAMGSGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAALGFPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMNKPPRNPKEPLISGWLFFRYLAIGCYVGAATVGAAAWWFIAADGGPRVTFYQLSHFLQCKEDNPDFEGVDCAVFESPYPMTMALSVLVTIEMCNALNSLSENQSLLRMPPWENIWLVGSICLSMSLHFLILYVEPLPLIFQITPLNLTQWLMVLKISLPVILMDETLKFVARNYLEPGKECVQPATKSCSFSACTDGISWPFVLLIMPLVIWVYSTDTNFSDMFWS", "length": 1042 }, "evidence": [ { "id": "A0A1L1RKB7", "url": "https://omabrowser.org/oma/group/A0A1L1RKB7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P16615-1", "protein_name": "Sarcoplasmic/endoplasmic reticulum calcium ATPase 2", "gene_name": "ATP2A2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MENAHTKTVEEVLGHFGVNESTGLSLEQVKKLKERWGSNELPAEEGKTLLELVIEQFEDLLVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEALKEYEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIAVGDKVPADIRLTSIKSTTLRVDQSILTGESVSVIKHTDPVPDPRAVNQDKKNMLFSGTNIAAGKAMGVVVATGVNTEIGKIRDEMVATEQERTPLQQKLDEFGEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAVALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCRMFILDRVEGDTCSLNEFTITGSTYAPIGEVHKDDKPVNCHQYDGLVELATICALCNDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTELKGLSKIERANACNSVIKQLMKKEFTLEFSRDRKSMSVYCTPNKPSRTSMSKMFVKGAPEGVIDRCTHIRVGSTKVPMTSGVKQKIMSVIREWGSGSDTLRCLALATHDNPLRREEMHLEDSANFIKYETNLTFVGCVGMLDPPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQDEDVTSKAFTGREFDELNPSAQRDACLNARCFARVEPSHKSKIVEFLQSFDEITAMTGDGVNDAPALKKAEIGIAMGSGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAALGFPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMNKPPRNPKEPLISGWLFFRYLAIGCYVGAATVGAAAWWFIAADGGPRVSFYQLSHFLQCKEDNPDFEGVDCAIFESPYPMTMALSVLVTIEMCNALNSLSENQSLLRMPPWENIWLVGSICLSMSLHFLILYVEPLPLIFQITPLNVTQWLMVLKISLPVILMDETLKFVARNYLEPGKECVQPATKSCSFSACTDGISWPFVLLIMPLVIWVYSTDTNFSDMFWS", "length": 1042 }, "evidence": [ { "id": "A0A1L1RKB7", "url": "https://omabrowser.org/oma/group/A0A1L1RKB7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P22700-1", "protein_name": "Calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type", "gene_name": "SERCA", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MEDGHSKTVEQSLNFFGTDPERGLTLDQIKANQKKYGPNELPTEEGKSIWQLVLEQFDDLLVKILLLAAIISFVLALFEEHEETFTAFVEPLVILLILIANAVVGVWQERNAESAIEALKEYEPEMGKVVRQDKSGIQKVRAKEIVPGDLVEVSVGDKIPADIRITHIYSTTLRIDQSILTGESVSVIKHTDAIPDPRAVNQDKKNILFSGTNVAAGKARGVVIGTGLSTAIGKIRTEMSETEEIKTPLQQKLDEFGEQLSKVISVICVAVWAINIGHFNDPAHGGSWIKGAIYYFKIAVALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVSRMFIFDKVEGNDSSFLEFEMTGSTYEPIGEVFLNGQRIKAADYDTLQELSTICIMCNDSAIDYNEFKQAFEKVGEATETALIVLAEKLNSFSVNKSGLDRRSAAIACRGEIETKWKKEFTLEFSRDRKSMSSYCTPLKASRLGTGPKLFVKGAPEGVLERCTHARVGTTKVPLTSALKAKILALTGQYGTGRDTLRCLALAVADSPMKPDEMDLGDSTKFYQYEVNLTFVGVVGMLDPPRKEVFDSIVRCRAAGIRVIVITGDNKATAEAICRRIGVFAEDEDTTGKSYSGREFDDLSPTEQKAAVARSRLFSRVEPQHKSKIVEFLQSMNEISAMTGDGVNDAPALKKAEIGIAMGSGTAVAKSAAEMVLADDNFSSIVSAVEEGRAIYNNMKQFIRYLISSNIGEVVSIFLTAALGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMEKPPRKADEGLISGWLFFRYMAIGFYVGAATVGAAAWWFVFSDEGPKLSYWQLTHHLSCLGGGDEFKGVDCKIFSDPHAMTMALSVLVTIEMLNAMNSLSENQSLITMPPWCNLWLIGSMALSFTLHFVILYVDVLSTVFQVTPLSAEEWITVMKFSIPVVLLDETLKFVARKIADGESPIYKMHGIVLMWAVFFGLLYAMML", "length": 1020 }, "evidence": [ { "id": "A0A1L1RKB7", "url": "https://omabrowser.org/oma/group/A0A1L1RKB7/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q03669-1", "protein_name": "Sarcoplasmic/endoplasmic reticulum calcium ATPase 2", "gene_name": "ATP2A2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MENAHTKTVEEVLAYFGVNESTGLSLEQVKKLKEKWGSNELPAEEGKTLLELVIEQFEDLLVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEALKEYEPEMGKVYRQDRKSVQRIKARDIVPGDIVEVAVGDKVPADIRITSIKSTTLRVDQSILTGESVSVIKHTDPVPDPRAVNQDKKNMLFSGTNIAAGKAMGVVIATGVNTEIGKIRDEMVATEQERTPLQQKLDEFGEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAVALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCRMFILDKVEGDSCSLNEFTVTGSTYAPMGEVHKDDKLIKCSQYDGLVELATICALCNDSSLDYNEAKGVYEKVGEATETALTCLVEKMNVFDTDLKGLSRIERANACNSVIKQLMKKEFTLEFSRDRKSMSVYCTPNKPSRTSMSKMFVKGAPEGVIDRCTHVRVGNAKIPLSSGIKQKIMSVIREWGTGRDTLRCLALATHDNPPRKEEMNLEDSSNFINYETNLTFVGCVGMLDPPRIEVASSIKLCKQAGIRVIMITGDNKGTAVAICRRIGIFVEDEDVSTKAFTGREFDELSLAAQRDACHHARCFARVEPSHKSKIVEFLQSFDEITAMTGDGVNDAPALKKAEIGIAMGSGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAALGFPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMNKPPRNPKEPLISGWLFFRYLAIGCYVGAATVGAAAWWFIAADGGPRVTFYQLSHFLQCKEDNPDFSGVDCVVFESPYPMTMALSVLVTIEMCNALNSLSENQSLMRMPPWENIWLVGAICLSMSLHFLILYVEPLPIIFQITPLNVTQWLMVLKISLPVILLDETLKYVARNYLEPGKDSVQPATKPCSLSACTEGVSWPFVFITLPLVIWLYSTDTNFSDMFW", "length": 1041 }, "evidence": [ { "id": "A0A1L1RKB7", "url": "https://omabrowser.org/oma/group/A0A1L1RKB7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q9SY55-1", "protein_name": "Calcium-transporting ATPase 3, endoplasmic reticulum-type", "gene_name": "ECA3", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEDAYARSVSEVLDFFGVDPTKGLSDSQVVHHSRLYGRNVLPEEKRTPFWKLVLKQFDDLLVKILIVAAIVSFVLALANGETGLTAFLEPFVILLILAANAAVGVITETNAEKALEELRAYQANIATVLRNGCFSILPATELVPGDIVEVTVGCKIPADLRMIEMSSNTFRVDQAILTGESCSVEKDVDCTLTTNAVYQDKKNILFSGTDVVAGRGRAVVIGVGSNTAMGSIHDSMLQTDDEATPLKKKLDEFGSFLAKVIAGICVLVWVVNIGHFSDPSHGGFFKGAIHYFKIAVALAVAAIPEGLPAVVTTCLALGTKKMARLNAIVRSLPSVETLGCTTVICSDKTGTLTTNMMSVSKICVVQSAEHGPMINEFTVSGTTYAPEGTVFDSNGMQLDLPAQSPCLHHLAMCSSLCNDSILQYNPDKDSYEKIGESTEVALRVLAEKVGLPGFDSMPSALNMLSKHERASYCNHYWENQFKKVYVLEFTRDRKMMSVLCSHKQMDVMFSKGAPESIIARCNKILCNGDGSVVPLTAAGRAELESRFYSFGDETLRCLALAFKTVPHGQQTISYDNENDLTFIGLVGMLDPPREEVRDAMLACMTAGIRVIVVTGDNKSTAESLCRKIGAFDNLVDFSGMSYTASEFERLPAVQQTLALRRMTLFSRVEPSHKRMLVEALQKQNEVVAMTGDGVNDAPALKKADIGIAMGSGTAVAKSASDMVLADDNFASIVAAVAEGRAIYNNTKQFIRYMISSNIGEVVCIFVAAVLGIPDTLAPVQLLWVNLVTDGLPATAIGFNKQDSDVMKAKPRKVGEAVVTGWLFFRYLVIGVYVGLATVAGFIWWFVYSDGGPKLTYSELMNFETCALRETTYPCSIFEDRHPSTVAMTVLVVVEMFNALNNLSENQSLLVITPRSNLWLVGSIILTMLLHVLILYVHPLAVLFSVTPLSWAEWTAVLYLSFPVIIIDELLKFLSRNTGMRFRFRLRKADLLPKDRRDK", "length": 998 }, "evidence": [ { "id": "A0A1L1RKB7", "url": "https://omabrowser.org/oma/group/A0A1L1RKB7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 9, "go_terms": [ { "name": "autophagosome assembly", "id": "GO:0000045", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000045", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RKB7", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RKB7" } ], "pmid": "" }, { "name": "intracellular calcium ion homeostasis", "id": "GO:0006874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006874", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RKB7", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RKB7" } ], "pmid": "" }, { "name": "calcium ion transmembrane transport", "id": "GO:0070588", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070588", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RKB7", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RKB7" } ], "pmid": "" }, { "name": "regulation of cardiac muscle contraction by calcium ion signaling", "id": "GO:0010882", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010882", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RKB7", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RKB7" } ], "pmid": "" }, { "name": "positive regulation of endoplasmic reticulum calcium ion concentration", "id": "GO:0032470", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032470", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RKB7", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RKB7" } ], "pmid": "" }, { "name": "calcium ion transport from cytosol to endoplasmic reticulum", "id": "GO:1903515", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903515", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RKB7", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RKB7" } ], "pmid": "" }, { "name": "calcium ion import into sarcoplasmic reticulum", "id": 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The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "platelet dense tubular network membrane", "input_participant_list": [ "R-ALL-427899", "R-ALL-74016" ], "output_participant_list": [ "R-ALL-139827" ], "enzyme_list": [ "Q9YGL9-2", "A0A1L1RKB7-1" ], "evidence": [ { "id": "R-GGA-418365", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-418365" } ] }, { "id": "R-GGA-427910", "name": "ATP2A1-3 transport Ca2+ from cytosol to ER lumen", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. 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0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "Q5ZK92-1", "uniprot_ac": "Q5ZK92", "uniprot_id": "SPAST_CHICK", "mass": { "chemical_mass": 66238.0, "monoisotopic_mass": 66238.0 }, "refseq": { "ac": "NP_001026232", "name": "spastin", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026232" }, "gene_names": [ { "name": "SPAST", "type": "recommended", "evidence": [ { "id": "Q5ZK92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZK92" } ] }, { "name": "RCJMB04_12e12", "type": "synonym", "evidence": [ { "id": "Q5ZK92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZK92" } ] }, { "name": "SPAST", "type": "synonym", "evidence": [ { "id": "NP_001026232", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026232" } ] }, { "name": "SPG4", "type": "synonym", "evidence": [ { "id": "NP_001026232", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026232" }, { "id": "Q5ZK92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZK92" } ] } ], "protein_names": [ { "name": "Spastin", "type": "recommended", "evidence": [ { "id": "Q5ZK92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZK92/entry#names_and_taxonomy" } ] }, { "name": "5.6.1.1", "type": "synonym", "evidence": [ { "id": "Q5ZK92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZK92/entry#names_and_taxonomy" } ] }, { "name": "neuronal spastin", "type": "synonym", "evidence": [ { "id": "NP_001026232", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026232" } ] }, { "name": "spastin", "type": "synonym", "evidence": [ { "id": "NP_001026232", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026232" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ720192.1, EU849599.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000063.1. On Sep 23, 2021 this sequence version replaced NP_001026232.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001026232", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026232" } ] }, { "annotation": "ATP-dependent microtubule severing protein that specifically recognizes and cuts microtubules that are polyglutamylated. Preferentially recognizes and acts on microtubules decorated with short polyglutamate tails: severing activity increases as the number of glutamates per tubulin rises from one to eight, but decreases beyond this glutamylation threshold. Microtubule severing promotes reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Required for membrane traffic from the endoplasmic reticulum (ER) to the Golgi and for completion of the abscission stage of cytokinesis. Also plays a role in axon growth and the formation of axonal branches.", "evidence": [ { "database": "UniProtKB", "id": "Q5ZK92", "url": "https://www.uniprot.org/uniprotkb/Q5ZK92#function" }, { "database": "HAMAP", "id": "MF_03021", "url": "https://hamap.expasy.org/signature/MF_03021" }, { "database": "UniProtKB", "id": "A0A8V0XN36", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XN36#function" }, { "database": "UniProtKB", "id": "A0A8V0XSD1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XSD1#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZK92", "url": "https://www.uniprot.org/uniprotkb/Q5ZK92" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SPAST", "url": "https://www.uniprot.org/uniprotkb/Q5ZK92", "locus": { "chromosome": "3", "start_pos": 33300516, "end_pos": 33337675, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010007251", "url": "https://www.ensembl.org/id/ENSGALG00010007251" } ] } } ], "crossref": [ { "id": "Q5ZK92", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZK92", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000010620", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000010620", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd02679", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02679", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd19524", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19524", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "421481", "url": "https://www.ncbi.nlm.nih.gov/gene/421481", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003593", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003593", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003959", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003959", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003960", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003960", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007330", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007330", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015415", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015415", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035106", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035106", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041569", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041569", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050304", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050304", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:421481", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421481", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KSREPML", "url": "https://omabrowser.org/oma/group/KSREPML/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1L1RV27", "url": "https://www.orthodb.org/?gene=A0A1L1RV27", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XN36", "url": "https://www.orthodb.org/?gene=A0A8V0XN36", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XSD1", "url": "https://www.orthodb.org/?gene=A0A8V0XSD1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "Q5ZK92", "url": "https://www.orthodb.org/?gene=Q5ZK92", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23074", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23074", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23074:SF86", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23074:SF86", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00004", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00004", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF09336", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09336", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17862", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17862", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5ZK92", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5ZK92", "database": "PRO", "categories": [ "Protein" ] }, { "id": "R-GGA-9668328", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9668328", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001026232", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026232", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1L1RV27", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RV27", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1L1RV27-1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RV27-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XN36", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XN36", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XN36-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XN36-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XSD1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XSD1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XSD1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XSD1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZK92", "url": "https://www.uniprot.org/uniprotkb/Q5ZK92", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZK92-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZK92-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZK92-2", "url": "https://www.uniprot.org/uniprotkb/Q5ZK92-2", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNSPGGRGKKKGSAGSSSAPPAAGASPSAPSGPAPPAPPAGAAAAAAASPHKRNLYYFSYPLFAAFALLRFVAFQLGLLVAWLCERLSRGALMAAKSSRAGDAPEPGGAAERVRACHKRAFECISMALRIDEDERAGQKEQAVEWYKKGIEELERGIAVLVVGQGDQCERARRLQSKMMTNLAMAKDRLQLLEKLQADLQISKPQMEVYNDSTNLACRNGHLQSESGAVPKKKDPLTHTSNSLPRSKTVAKTGSTGLSGHHRTPSYSGISTASVSRPAANPATSTHKAAPKNSRTNKPSTPTPAARKKKDTKVFRNVDSNLANLILNEIVDSGPAVKFDDIAGQELAKQALQEIVILPSLRPELFTGLRAPARGLLLFGPPGNGKTMLAKAVAAESNATFFNISAASLTSKYVGEGEKLVRALFAVARELQPSIIFIDEVDSLLCERREGEHDASRRLKTEFLIEFDGVQSSGEDRILVMGATNRPQELDDAVLRRFTKRVYVSLPNEETRLILLKNLLSKQGSPLTQKELAQLARMTDGYSGSDLTALAKDAALGPIRELKPEQVKNMSASEMRNIKLSDFTESLKKIKRSLSPQTLEAYIRWNKDFGDTTV", "length": 613, "header": "sp|Q5ZK92-1|SPAST_CHICK Isoform 1 of Spastin OS=Gallus gallus OX=9031 GN=SPAST PE=2 SV=2 CANONICAL=Q5ZK92-1" }, "isoforms": [ { "isoform_ac": "A0A1L1RV27-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZK92/entry#A0A1L1RV27-1", "sequence": { "sequence": "MNSPGGRGKKKGSAGSSSAPPAAGASPSAPSGPAPPAPPAGAAAAAAASPHKRNLYYFSYPLFAAFALLRFVAFQLGLLVAWLCERLSRGALMAAKSSRAGDAPEPGGAAERVRACHKRAFECISMALRIDEDEREKLQADLQISKPQMEVYNDSTNLACRNGHLQSESGAVPKKKDPLTHTSNSLPRSKTVAKTGSTGLSGHHRTPSYSGISTASVSRPAANPATSTHKAAPKNSRTNKPSTPTPAARKKKDTKVFRNVDSNLANLILNEIVDSGPAVKFDDIAGQELAKQALQEIVILPSLRPELFTGLRAPARGLLLFGPPGNGKTMLAKAVAAESNATFFNISAASLTSKYVGEGEKLVRALFAVARELQPSIIFIDEVDSLLCERREGEHDASRRLKTEFLIEFDGVQSSGEDRILVMGATNRPQELDDAVLRRFTKRVYVSLPNEETRLILLKNLLSKQGSPLTQKELAQLARMTDGYSGSDLTALAKDAALGPIRELKPEQVKNMSASEMRNIKLSDFTESLKKIKRSLSPQTLEAYIRWNKDFGDTTV", "length": 556, "header": "tr|A0A1L1RV27-1|SPAST_CHICK Computationally mapped isoform of Spastin OS=Gallus gallus OX=9031 GN=SPAST PE=2 SV=2 CANONICAL=Q5ZK92-1" }, "locus": { "chromosome": "3", "start_pos": 33337453, "end_pos": 33305472, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010017313.1", "url": "https://www.ensembl.org/id/ENSGALT00010017313.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010009589.1", "url": "https://www.ensembl.org/id/ENSGALP00010009589.1" } ] } }, { "isoform_ac": "A0A8V0XN36-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZK92/entry#A0A8V0XN36-1", "sequence": { "sequence": "MNSPGGRGKKKGSAGSSSAPPAAGASPSAPSGPAPPAPPAGAAAAAAASPHKRNLYYFSYPLFAAFALLRFVAFQLGLLVAWLCERLSRGALMAAKSSRAGDAPEPGGAAERVRACHKRAFECISMALRIDEDERAGQKEQAVEWYKKGIEELERGIAVLVVGQEKLQADLQISKPQMEVYNDSTNLACRNGHLQSESGAVPKKKDPLTHTSNSLPRSKTVAKTGSTGLSGHHRTPSYSGISTASVSRPAANPATSTHKAAPKNSRTNKPSTPTPAARKKKDTKVFRNVDSNLANLILNEIVDSGPAVKFDDIAGQELAKQALQEIVILPSLRPELFTGLRAPARGLLLFGPPGNGKTMLAKAVAAESNATFFNISAASLTSKYVGEGEKLVRALFAVARELQPSIIFIDEVDSLLCERREGEHDASRRLKTEFLIEFDGVQSSGEDRILVMGATNRPQELDDAVLRRFTKRVYVSLPNEETRLILLKNLLSKQGSPLTQKELAQLARMTDGYSGSDLTALAKDAALGPIRELKPEQVKNMSASEMRNIKLSDFTESLKKIKRSLSPQTLEAYIRWNKDFGDTTV", "length": 585, "header": "tr|A0A8V0XN36-1|A0A8V0XN36_CHICK Computationally mapped isoform of Spastin OS=Gallus gallus OX=9031 GN=SPAST PE=1 SV=1 CANONICAL=Q5ZK92-1" }, "locus": { "chromosome": "3", "start_pos": 33337453, "end_pos": 33305472, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010017324.1", "url": "https://www.ensembl.org/id/ENSGALT00010017324.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010009595.1", "url": "https://www.ensembl.org/id/ENSGALP00010009595.1" } ] } }, { "isoform_ac": "A0A8V0XSD1-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZK92/entry#A0A8V0XSD1-1", "sequence": { "sequence": "MNSPGGRGKKKGSAGSSSAPPAAGASPSAPSGPAPPAPPAGAAAAAAASPHKRNLYYFSYPLFAAFALLRFVAFQLGLLVAWLCERLSRGALMAAKSSRAGDAPEPGGAAERVRACHKRAFECISMALRIDEDERAGQKEQAVEWYKKGIEELERGIAVLVVGQGDQCERARRLQSKMMTNLAMAKDRLQLLEKLQADLQISKPQMEVYNDSTNLACRNGHLQSESGAVPKKKDPLTHTSNSLPRSKTVAKTGSTGLSGHHRTPSYSGISTASVSRPAANPATSTHKAAPKNSRTNKPSTPTPAARKKKDTKVFRNVDSNLANLILNEIVDSGPAVKFDDIAGQELAKQALQEIVILPSLRPELFTGLRAPARGLLLFGPPGNGKTMLAKAVAAESNATFFNISAASLTSKYVGEGEKLVRALFAVARELQPSIIFIDEVDSLLCERREGEHDASRRLKTEFLIEFDGVQSSGEDRILVMGATNRPQELDDAVLRYQNLFSYMSTRLILLKNLLSKQGSPLTQKELAQLARMTDGYSGSDLTALAKDAALGPIRELKPEQVKNMSASEMRNIKLSDFTESLKKIKRSLSPQTLEAYIRWNKDFGDTTV", "length": 608, "header": "tr|A0A8V0XSD1-1|A0A8V0XSD1_CHICK Computationally mapped isoform of Spastin OS=Gallus gallus OX=9031 GN=SPAST PE=1 SV=1 CANONICAL=Q5ZK92-1" }, "locus": { "chromosome": "3", "start_pos": 33337453, "end_pos": 33305472, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010017322.1", "url": "https://www.ensembl.org/id/ENSGALT00010017322.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010009594.1", "url": "https://www.ensembl.org/id/ENSGALP00010009594.1" } ] } }, { "isoform_ac": "Q5ZK92-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZK92/entry#Q5ZK92-1", "sequence": { "sequence": "MNSPGGRGKKKGSAGSSSAPPAAGASPSAPSGPAPPAPPAGAAAAAAASPHKRNLYYFSYPLFAAFALLRFVAFQLGLLVAWLCERLSRGALMAAKSSRAGDAPEPGGAAERVRACHKRAFECISMALRIDEDERAGQKEQAVEWYKKGIEELERGIAVLVVGQGDQCERARRLQSKMMTNLAMAKDRLQLLEKLQADLQISKPQMEVYNDSTNLACRNGHLQSESGAVPKKKDPLTHTSNSLPRSKTVAKTGSTGLSGHHRTPSYSGISTASVSRPAANPATSTHKAAPKNSRTNKPSTPTPAARKKKDTKVFRNVDSNLANLILNEIVDSGPAVKFDDIAGQELAKQALQEIVILPSLRPELFTGLRAPARGLLLFGPPGNGKTMLAKAVAAESNATFFNISAASLTSKYVGEGEKLVRALFAVARELQPSIIFIDEVDSLLCERREGEHDASRRLKTEFLIEFDGVQSSGEDRILVMGATNRPQELDDAVLRRFTKRVYVSLPNEETRLILLKNLLSKQGSPLTQKELAQLARMTDGYSGSDLTALAKDAALGPIRELKPEQVKNMSASEMRNIKLSDFTESLKKIKRSLSPQTLEAYIRWNKDFGDTTV", "length": 613, "header": "sp|Q5ZK92-1|SPAST_CHICK Isoform 1 of Spastin OS=Gallus gallus OX=9031 GN=SPAST PE=2 SV=2 CANONICAL=Q5ZK92-1" }, "locus": { "chromosome": "3", "start_pos": 33337453, "end_pos": 33305472, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010017319.1", "url": "https://www.ensembl.org/id/ENSGALT00010017319.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010009593.1", "url": "https://www.ensembl.org/id/ENSGALP00010009593.1" } ] } }, { "isoform_ac": "Q5ZK92-2", "url": "https://www.uniprot.org/uniprotkb/Q5ZK92/entry#Q5ZK92-2", "sequence": { "sequence": "MNSPGGRGKKKGSAGSSSAPPAAGASPSAPSGPAPPAPPAGAAAAAAASPHKRNLYYFSYPLFAAFALLRFVAFQLGLLVAWLCERLSRGALMAAKSSRAGDAPEPGGAAERVRACHKRAFECISMALRIDEDERAGQKEQAVEWYKKGIEELERGIAVLVVGQGDQCERARRLQSKMMTNLAMAKDRLQLLESGAVPKKKDPLTHTSNSLPRSKTVAKTGSTGLSGHHRTPSYSGISTASVSRPAANPATSTHKAAPKNSRTNKPSTPTPAARKKKDTKVFRNVDSNLANLILNEIVDSGPAVKFDDIAGQELAKQALQEIVILPSLRPELFTGLRAPARGLLLFGPPGNGKTMLAKAVAAESNATFFNISAASLTSKYVGEGEKLVRALFAVARELQPSIIFIDEVDSLLCERREGEHDASRRLKTEFLIEFDGVQSSGEDRILVMGATNRPQELDDAVLRRFTKRVYVSLPNEETRLILLKNLLSKQGSPLTQKELAQLARMTDGYSGSDLTALAKDAALGPIRELKPEQVKNMSASEMRNIKLSDFTESLKKIKRSLSPQTLEAYIRWNKDFGDTTV", "length": 581, "header": "sp|Q5ZK92-2|SPAST_CHICK Isoform 2 of Spastin OS=Gallus gallus OX=9031 GN=SPAST PE=2 SV=2 CANONICAL=Q5ZK92-1" }, "locus": { "chromosome": "3", "start_pos": 33337453, "end_pos": 33305472, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010017325.1", "url": "https://www.ensembl.org/id/ENSGALT00010017325.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010009596.1", "url": "https://www.ensembl.org/id/ENSGALP00010009596.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 302, "start_aa": "Thr", "end_pos": 302, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr302", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "Sequence and comparative analysis of the chicken genome provide unique perspectives on vertebrate evolution.", "journal": "Nature", "date": "2004", "authors": "", "evidence": [ { "database": "UniProtKB", "id": "Q5ZK92", "url": "https://www.uniprot.org/uniprotkb/Q5ZK92" } ], "reference": [ { "type": "PubMed", "id": "15592404", "url": "https://glygen.org/publication/PubMed/15592404" } ] }, { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5ZK92", "url": "https://www.uniprot.org/uniprotkb/Q5ZK92" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:421481", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421481", "resource": "KEGG Pathway" }, { "id": "R-GGA-9668328", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9668328", "resource": "Reactome", "description": "Sealing of the nuclear envelope (NE) by ESCRT-III" } ], "orthologs": [ { "uniprot_canonical_ac": "A2VDN5-1", "protein_name": "Spastin", "gene_name": "SPAST", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNSPGGRGKKKGSGGPSSPVPPRPPPPCQARSRPAPKPAPPPQSPHKRNLYYFSYPLFLGFALLRLVAFHLGLLFVWLCQRFSRALMAAKRSSGAAPASASPPAPVPGGEAERVRAFHKQAFEYISVALRIDEDEKVGQKDQAVEWYKKGIEELEKGIAVVVTGQGEQCERARRLQAKMMTNLVMAKDRLQLLEKLQPSLQFSKSQTDVYNDSTNLTCRNGHLQSESGAVPKRKDPLTHASNSLPRSKTVMKTGPTGLSGHHRAPSCSGLSMVSGVRQGPGSAAATHKSTPKTNRTNKPSTPTTAARKKKDLKNFRNVDSNLANLIMNEIVDNGTAVKFDDIAGQELAKQALQEIVILPSLRPELFTGLRAPARGLLLFGPPGNGKTMLAKAVAAESNATFFNISAASLTSKYVGEGEKLVRALFAVARELQPSIIFIDEVDSLLCERREGEHDASRRLKTEFLIEFDGVQSAGDDRVLVMGATNRPQELDEAVLRRFTKRVYVSLPNEETRLLLLKNLLCKQGSPLTQKELAQLARMTNGYSGSDLTALAKDAALGPIRELKPEQVKNMSASEMRNIRLSDFTESLKKIKRSVSPQTLEAYIRWNKDFGDTTV", "length": 614 }, "evidence": [ { "id": "Q5ZK92", "url": "https://omabrowser.org/oma/group/Q5ZK92/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "B2RYN7-1", "protein_name": "Spastin", "gene_name": "Spast", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSPAGRRKKKGSGGASPAPARPPPPAAVPAPAAGPAPAPGSPHKRNLYYFSYPLVVGFALLRLLACHLGLLFVWLCQRFSRALMAAKRSSGTAPAPASPSTPAPGPGGEAESVRVFHKQAFEYISIALRIDEEEKGQKEQAVEWYKKGIEELEKGIAVIVTGQGEQYERARRLQAKMMTNLVMAKDRLQLLESGAVPKKKDPLTHASNSLPRSKTVMKSGSTGLSGHHRAPSCSGLSMVSGARPGSGPAATTHKGTSKPNRTNKPSTPTTAVRKKKDLKNFRNVDSNLANLIMNEIVDNGTAVKFDDIAGQELAKQALQEIVILPSLRPELFTGLRAPARGLLLFGPPGNGKTMLAKAVAAESNATFFNISAASLTSKYVGEGEKLVRALFAVARELQPSIIFIDEVDSLLCERREGEHDASRRLKTEFLIEFDGVQSAGDDRVLVMGATNRPQELDEAVLRRFIKRVYVSLPNEETRLLLLKNLLCKQGSPLTQKELAQLARMTDGYSGSDLTALAKDAALGPIRELKPEQVKNMSASEMRNIRLSDFTESLKKIKRSVSPQTLEAYIRWNKDFGDTTV", "length": 581 }, "evidence": [ { "id": "Q5ZK92", "url": "https://omabrowser.org/oma/group/Q5ZK92/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6NW58-1", "protein_name": "Spastin", "gene_name": "spast", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNSGHKARLRGGRACGPVSDGSARGNRLLFYTRSLSRVPEWLLRVLLLLLRWLFQPIRRAMAARAKECGPDGSEETGERIRNYHKQAFEFISVALQIDEDEKGDKQKAVQWYRKGIAELEKGIQIQVTGAGEKADRARKLQDKMITNLSMAEDRLKLLGNLLSQSPAESSSDDSFYSFSNGNLRPAPASGAVSKKKDTLTITNQTSLRPKNPPKSTPNASGLNCTPSAAQSSRTGPQNNQKGPTVKGKNNVKASTTATASPQRKRDMKNFKNVDSKLASLILNEIVDSGSVVRFDDIAGQDLAKQALQEIVILPALRPELFTGLRAPARGLLLFGPPGNGKTMLAKAVAMESNATFFNISAATLTSKYVGEGEKLVRALFAVARELQPSIIFIDEIDSLLCERREGEHDASRRLKTEFLIEFDGVQSGGDERVLVMGATNRPQELDEAVLRRFAKRIYVALPTEETRLKLLKNLLSKHRNPLSQKELSQLARLTDGYSGSDLTSLAKDAALGPIRELKPEQVRNMSAHEMRDIRISDFLESLKRIKRSVSPQTLDQYVRWNREYGDTTGV", "length": 570 }, "evidence": [ { "id": "Q5ZK92", "url": "https://omabrowser.org/oma/group/Q5ZK92/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8I0P1-1", "protein_name": "Spastin", "gene_name": "spas", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MVRTKNQSSSSSASSSSTKSPIKSSSGAGSSGGGLGGRQSTHRSSSASNVAAVVAGGSSAAGGGSSSNRRSPGSSPDGDDDTTTTDDLTPTTCSPRSGHHHSYGGYSSSVHKQNLYVVSFPIIFLFNVLRSLIYQLFCIFRYLYGASTKVIYRPHRRDCNIEIVVQNSSKEQQQSLNHPSELNREGDGQEQQLSNQPQRFRPIQPLEMAANRPGGGYSPGPGDPLLAKQKHHHRRAFEYISKALKIDEENEGHKELAIELYRKGIKELEDGIAVDCWSGRGDVWDRAQRLHDKMQTNLSMARDRLHFLALREQDLQMQRLSLKEKQKEEAQSKPQKTREPMLAGMTNEPMKLRVRSSGYGPKATTSAQPTASGRKLTIGSKRPVNLAVANKSQTLPRNLGSKTSVGAVQRQPAKTAATPPAVRRQFSSGRNTPPQRSRTPINNNGPSGSGASTPVVSVKGVEQKLVQLILDEIVEGGAKVEWTDIAGQDVAKQALQEMVILPSVRPELFTGLRAPAKGLLLFGPPGNGKTLLARAVATECSATFLNISAASLTSKYVGDGEKLVRALFAVARHMQPSIIFIDEVDSLLSERSSSEHEASRRLKTEFLVEFDGLPGNPDGDRIVVLAATNRPQELDEAALRRFTKRVYVSLPDEQTRELLLNRLLQKQGSPLDTEALRRLAKITDGYSGSDLTALAKDAALEPIRELNVEQVKCLDISAMRAITEQDFHSSLKRIRRSVAPQSLNSYEKWSQDYGDITI", "length": 758 }, "evidence": [ { "id": "Q5ZK92", "url": "https://omabrowser.org/oma/group/Q5ZK92/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9QYY8-1", "protein_name": "Spastin", "gene_name": "Spast", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSPAGRRKKKGSGGASPAPARPPPPAAVPAPAAGPAPAAGSPPKRNPSSFSSPLVVGFALLRLLACHLGLLFAWLCQRFSRALMAAKRSSGTAPAPASPSPPEPGPGGEAESVRVFHKQAFEYISIALRIDEEEKAGQKEQAVEWYKKGIEELEKGIAVIVTGQGEQYERARRLQAKMMTNLVMAKDRLQLLEKLQPVLQFSKSQTDVYNESTNLTCRNGHLQSESGAVPKRKDPLTHASNSLPRSKTVLKSGSAGLSGHHRAPSCSGLSMVSGARPGPGPAATTHKGTPKPNRTNKPSTPTTAVRKKKDLKNFRNVDSNLANLIMNEIVDNGTAVKFDDIAGQELAKQALQEIVILPSLRPELFTGLRAPARGLLLFGPPGNGKTMLAKAVAAESNATFFNISAASLTSKYVGEGEKLVRALFAVARELQPSIIFIDEVDSLLCERREGEHDASRRLKTEFLIEFDGVQSAGDDRVLVMGATNRPQELDEAVLRRFIKRVYVSLPNEETRLLLLKNLLCKQGSPLTQKELAQLARMTDGYSGSDLTALAKDAALGPIRELKPEQVKNMSASEMRNIRLSDFTESLKKIKRSVSPQTLEAYIRWNKDFGDTTV", "length": 614 }, "evidence": [ { "id": "Q5ZK92", "url": "https://omabrowser.org/oma/group/Q5ZK92/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9UBP0-1", "protein_name": "Spastin", "gene_name": "SPAST", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNSPGGRGKKKGSGGASNPVPPRPPPPCLAPAPPAAGPAPPPESPHKRNLYYFSYPLFVGFALLRLVAFHLGLLFVWLCQRFSRALMAAKRSSGAAPAPASASAPAPVPGGEAERVRVFHKQAFEYISIALRIDEDEKAGQKEQAVEWYKKGIEELEKGIAVIVTGQGEQCERARRLQAKMMTNLVMAKDRLQLLEKMQPVLPFSKSQTDVYNDSTNLACRNGHLQSESGAVPKRKDPLTHTSNSLPRSKTVMKTGSAGLSGHHRAPSYSGLSMVSGVKQGSGPAPTTHKGTPKTNRTNKPSTPTTATRKKKDLKNFRNVDSNLANLIMNEIVDNGTAVKFDDIAGQDLAKQALQEIVILPSLRPELFTGLRAPARGLLLFGPPGNGKTMLAKAVAAESNATFFNISAASLTSKYVGEGEKLVRALFAVARELQPSIIFIDEVDSLLCERREGEHDASRRLKTEFLIEFDGVQSAGDDRVLVMGATNRPQELDEAVLRRFIKRVYVSLPNEETRLLLLKNLLCKQGSPLTQKELAQLARMTDGYSGSDLTALAKDAALGPIRELKPEQVKNMSASEMRNIRLSDFTESLKKIKRSVSPQTLEAYIRWNKDFGDTTV", "length": 616 }, "evidence": [ { "id": "Q5ZK92", "url": "https://omabrowser.org/oma/group/Q5ZK92/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 17, "go_terms": [ { "name": "nuclear membrane reassembly", "id": "GO:0031468", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031468", "evidence": [ { "database": "UniProtKB", "id": "Q5ZK92", "url": "https://www.uniprot.org/uniprotkb/Q5ZK92" } ], "pmid": "" }, { "name": "microtubule severing", "id": "GO:0051013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051013", "evidence": [ { "database": "UniProtKB", "id": "Q5ZK92", "url": "https://www.uniprot.org/uniprotkb/Q5ZK92" } ], "pmid": "" }, { "name": "positive regulation of microtubule depolymerization", "id": "GO:0031117", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031117", "evidence": [ { "database": "UniProtKB", "id": "Q5ZK92", "url": "https://www.uniprot.org/uniprotkb/Q5ZK92" } ], "pmid": "" }, { "name": "protein homooligomerization", "id": "GO:0051260", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051260", "evidence": [ { "database": "UniProtKB", "id": "Q5ZK92", "url": "https://www.uniprot.org/uniprotkb/Q5ZK92" } ], "pmid": "" }, { "name": "endoplasmic reticulum to Golgi vesicle-mediated transport", "id": "GO:0006888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006888", "evidence": [ { "database": "UniProtKB", "id": "Q5ZK92", "url": "https://www.uniprot.org/uniprotkb/Q5ZK92" } ], "pmid": "" }, { "name": "exit from mitosis", "id": "GO:0010458", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010458", "evidence": [ { "database": "UniProtKB", "id": "Q5ZK92", "url": "https://www.uniprot.org/uniprotkb/Q5ZK92" } ], "pmid": "" }, { "name": "mitotic cytokinesis", "id": "GO:0000281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000281", "evidence": [ { "database": "UniProtKB", "id": "Q5ZK92", "url": "https://www.uniprot.org/uniprotkb/Q5ZK92" } ], "pmid": "" }, { "name": "anterograde axonal transport", "id": "GO:0008089", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008089", "evidence": [ { "database": "UniProtKB", "id": "Q5ZK92", "url": "https://www.uniprot.org/uniprotkb/Q5ZK92" } ], "pmid": "" }, { "name": "cytokinetic process", "id": "GO:0032506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032506", "evidence": [ { "database": "UniProtKB", "id": "Q5ZK92", "url": "https://www.uniprot.org/uniprotkb/Q5ZK92" } ], "pmid": "" }, { "name": "central nervous system neuron axonogenesis", "id": "GO:0021955", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021955", "evidence": [ { "database": "UniProtKB", "id": "Q5ZK92", "url": "https://www.uniprot.org/uniprotkb/Q5ZK92" } ], "pmid": "" }, { "name": "mitotic spindle disassembly", "id": "GO:0051228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051228", "evidence": [ { "database": "UniProtKB", "id": "Q5ZK92", "url": "https://www.uniprot.org/uniprotkb/Q5ZK92" } ], "pmid": "" }, { "name": "positive regulation of cytokinesis", "id": "GO:0032467", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032467", "evidence": [ { "database": "UniProtKB", "id": "Q5ZK92", "url": "https://www.uniprot.org/uniprotkb/Q5ZK92" } ], "pmid": "" }, { "name": "microtubule bundle formation", "id": "GO:0001578", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001578", "evidence": [ { "database": "UniProtKB", "id": "Q5ZK92", "url": "https://www.uniprot.org/uniprotkb/Q5ZK92" } ], "pmid": "" }, { "name": "membrane fission", "id": "GO:0090148", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090148", "evidence": [ { "database": "UniProtKB", "id": "Q5ZK92", "url": "https://www.uniprot.org/uniprotkb/Q5ZK92" } ], "pmid": "" }, { "name": "protein hexamerization", "id": "GO:0034214", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034214", "evidence": [ { "database": "UniProtKB", "id": "Q5ZK92", "url": "https://www.uniprot.org/uniprotkb/Q5ZK92" } ], "pmid": "" }, { "name": "axonal transport of mitochondrion", "id": "GO:0019896", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019896", "evidence": [ { "database": "UniProtKB", "id": "Q5ZK92", "url": "https://www.uniprot.org/uniprotkb/Q5ZK92" } ], "pmid": "" }, { "name": "axonogenesis", "id": "GO:0007409", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007409", "evidence": [ { "database": "UniProtKB", "id": "Q5ZK92", "url": "https://www.uniprot.org/uniprotkb/Q5ZK92" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "microtubule severing ATPase activity", "id": "GO:0008568", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008568", "evidence": [ { "database": "UniProtKB", "id": "Q5ZK92", "url": "https://www.uniprot.org/uniprotkb/Q5ZK92" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q5ZK92", "url": "https://www.uniprot.org/uniprotkb/Q5ZK92" } ], "pmid": "" }, { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "Q5ZK92", "url": "https://www.uniprot.org/uniprotkb/Q5ZK92" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "Q5ZK92", "url": "https://www.uniprot.org/uniprotkb/Q5ZK92" } ], "pmid": "" }, { "name": "beta-tubulin binding", "id": "GO:0048487", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048487", "evidence": [ { "database": "UniProtKB", "id": "Q5ZK92", "url": "https://www.uniprot.org/uniprotkb/Q5ZK92" } ], "pmid": "" }, { "name": "alpha-tubulin binding", "id": "GO:0043014", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043014", "evidence": [ { "database": "UniProtKB", "id": "Q5ZK92", "url": "https://www.uniprot.org/uniprotkb/Q5ZK92" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 15, "go_terms": [ { "name": "spindle pole", "id": "GO:0000922", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000922", "evidence": [ { "database": "UniProtKB", "id": "Q5ZK92", "url": "https://www.uniprot.org/uniprotkb/Q5ZK92" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q5ZK92", "url": "https://www.uniprot.org/uniprotkb/Q5ZK92" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "Q5ZK92", "url": "https://www.uniprot.org/uniprotkb/Q5ZK92" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q5ZK92", "url": "https://www.uniprot.org/uniprotkb/Q5ZK92" } ], "pmid": "" }, { "name": "endosome", "id": "GO:0005768", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005768", "evidence": [ { "database": "UniProtKB", "id": "Q5ZK92", "url": "https://www.uniprot.org/uniprotkb/Q5ZK92" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "Q5ZK92", "url": "https://www.uniprot.org/uniprotkb/Q5ZK92" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "Q5ZK92", "url": "https://www.uniprot.org/uniprotkb/Q5ZK92" } ], "pmid": "" }, { "name": "spindle", "id": "GO:0005819", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005819", "evidence": [ { "database": "UniProtKB", "id": "Q5ZK92", "url": "https://www.uniprot.org/uniprotkb/Q5ZK92" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q5ZK92", "url": "https://www.uniprot.org/uniprotkb/Q5ZK92" } ], "pmid": "" }, { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "Q5ZK92", "url": "https://www.uniprot.org/uniprotkb/Q5ZK92" } ], "pmid": "" }, { "name": "nuclear membrane", "id": "GO:0031965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031965", "evidence": [ { "database": "UniProtKB", "id": "Q5ZK92", "url": "https://www.uniprot.org/uniprotkb/Q5ZK92" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "Q5ZK92", "url": "https://www.uniprot.org/uniprotkb/Q5ZK92" } ], "pmid": "" }, { "name": "midbody", "id": "GO:0030496", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030496", "evidence": [ { "database": "UniProtKB", "id": "Q5ZK92", "url": "https://www.uniprot.org/uniprotkb/Q5ZK92" } ], "pmid": "" }, { "name": "axon cytoplasm", "id": "GO:1904115", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904115", "evidence": [ { "database": "UniProtKB", "id": "Q5ZK92", "url": "https://www.uniprot.org/uniprotkb/Q5ZK92" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q5ZK92", "url": "https://www.uniprot.org/uniprotkb/Q5ZK92" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 210, "end_pos": 212, "annotation": "n_glycosylation_sequon" }, { "start_pos": 397, "end_pos": 399, "annotation": "n_glycosylation_sequon" }, { "start_pos": 402, "end_pos": 404, "annotation": "n_glycosylation_sequon" }, { "start_pos": 568, "end_pos": 570, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-GGA-9668389", "name": "VPS4 binds ESCRT-III assemblies at nuclear envelope (NE) fenestrations", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, nuclear envelope", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q5ZK92-1", "A0A8V0XWR3-1" ], "evidence": [ { "id": "R-GGA-9668389", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9668389" } ] }, { "id": "R-GGA-9668405", "name": "SPAST (spastin) binds the IST1 subunit of ESCRT-III at the sites of microtubule attachment to chromatin", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, nuclear envelope", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q5ZK92-1" ], "evidence": [ { "id": "R-GGA-9668405", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9668405" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0XWR3", "gene_name": "VPS4A", "activity": [ { "ec_number": "3.6.4.6", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XWR3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XWR3" } ] }, { "ec_number": "3.6.4.6", "activity": "", "evidence": [ { "id": "A0A8V0XWR3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XWR3" } ] } ] }, { "uniprot_ac": "Q5ZK92", "gene_name": "SPAST", "activity": [ { "ec_number": "5.6.1.1", "activity": "n ATP + n H2O + a microtubule = n ADP + n phosphate + (n+1) alpha/beta tubulin heterodimers.", "evidence": [ { "id": "Q5ZK92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZK92" } ] }, { "ec_number": "5.6.1.1", "activity": "", "evidence": [ { "id": "Q5ZK92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZK92" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q5ZK92-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 613, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q5ZK92-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q5ZK92" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q5ZK92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZK92" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "MIT", "eco_id": "ECO_0000255", "start_pos": 117, "end_pos": 192, "start_aa": "His", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "5.6.1.1", "ec_name": "n ATP + n H2O + a microtubule = n ADP + n phosphate + (n+1) alpha/beta tubulin heterodimers.", "evidence": [ { "id": "5.6.1.1", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=5.6.1.1" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 302 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 210, "end_pos": 212 }, { "start_pos": 397, "end_pos": 399 }, { "start_pos": 402, "end_pos": 404 }, { "start_pos": 568, "end_pos": 570 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": 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"https://www.ncbi.nlm.nih.gov/protein/NP_990657" }, { "id": "P22448", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P22448" } ] }, { "name": "RARBETA", "type": "synonym", "evidence": [ { "id": "NP_990657", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990657" } ] }, { "name": "RARB", "type": "synonym", "evidence": [ { "id": "NP_990657", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990657" } ] } ], "protein_names": [ { "name": "Retinoic acid receptor beta", "type": "recommended", "evidence": [ { "id": "P22448", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P22448/entry#names_and_taxonomy" } ] }, { "name": "Nuclear receptor subfamily 1 group B member 2", "type": "synonym", "evidence": [ { "id": "P22448", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P22448/entry#names_and_taxonomy" } ] }, { "name": "RAR-beta", "type": "synonym", "evidence": [ { "id": "NP_990657", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990657" }, { "id": "P22448", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P22448/entry#names_and_taxonomy" } ] }, { "name": "nuclear receptor subfamily 1 group B member 2", "type": "synonym", "evidence": [ { "id": "NP_990657", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990657" } ] }, { "name": "retinoic acid receptor beta 2", "type": "synonym", "evidence": [ { "id": "NP_990657", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990657" } ] }, { "name": "retinoic acid receptor beta4'", "type": "synonym", "evidence": [ { "id": "NP_990657", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990657" } ] }, { "name": "retinoic acid receptor beta4M'", "type": "synonym", "evidence": [ { "id": "NP_990657", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990657" } ] }, { "name": "retinoic acid receptor beta", "type": "synonym", "evidence": [ { "id": "NP_990657", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990657" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: X57341.1, SRR13267656.13968.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992393 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000037.1. Sequence Note: This sequence has been modified as follows: removed 36 bp suspected to be vector contamination from the 3' end. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.", "evidence": [ { "database": "RefSeq", "id": "NP_990657", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990657" } ] }, { "annotation": "Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5 (By similarity). Required for limb and craniofacial development.", "evidence": [ { "database": "UniProtKB", "id": "P22448", "url": "https://www.uniprot.org/uniprotkb/P22448#function" }, { "database": "PubMed", "id": "1652423", "url": "https://glygen.org/publication/PubMed/1652423" }, { "database": "PubMed", "id": "7703521", "url": "https://glygen.org/publication/PubMed/7703521" } ] }, { "annotation": "Study showed that RARB expression was vital for the timely execution of programmed cell death and was furthermore seen to have an influence on the differentiation state of the ciliary ganglion neurons", "evidence": [ { "database": "RefSeq", "id": "NP_990657", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990657" }, { "database": "PubMed", "id": "25663354", "url": "https://glygen.org/publication/PubMed/25663354" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "P22448", "url": "https://www.uniprot.org/uniprotkb/P22448" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RARB", "url": "https://www.uniprot.org/uniprotkb/P22448", "locus": { "chromosome": "2", "start_pos": 37746383, "end_pos": 37422055, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010002438", "url": "https://www.ensembl.org/id/ENSGALG00010002438" } ] } } ], "crossref": [ { "id": "P22448", "url": "https://alphafold.ebi.ac.uk/entry/P22448", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000011298", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000011298", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd06937", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06937", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd06964", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06964", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "396266", "url": "https://www.ncbi.nlm.nih.gov/gene/396266", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000536", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000536", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001628", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001628", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001723", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001723", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003078", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003078", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013088", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013088", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035500", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035500", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047158", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047158", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047159", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047159", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:396266", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:396266", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TDWQHRH", "url": "https://omabrowser.org/oma/group/TDWQHRH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1N8XGG5", "url": "https://www.orthodb.org/?gene=A0A1N8XGG5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0X5W1", "url": "https://www.orthodb.org/?gene=A0A8V0X5W1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XA05", "url": "https://www.orthodb.org/?gene=A0A8V0XA05", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XD11", "url": "https://www.orthodb.org/?gene=A0A8V0XD11", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XFP9", "url": "https://www.orthodb.org/?gene=A0A8V0XFP9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XGJ5", "url": "https://www.orthodb.org/?gene=A0A8V0XGJ5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XGL7", "url": "https://www.orthodb.org/?gene=A0A8V0XGL7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "P22448", "url": "https://www.orthodb.org/?gene=P22448", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24085", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24085", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24085:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24085:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00104", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00104", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00105", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00105", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:P22448", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:P22448", "database": "PRO", "categories": [ "Protein" ] }, { "id": "R-GGA-383280", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-383280", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_990657", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990657", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1N8XGG5", "url": "https://www.uniprot.org/uniprotkb/A0A1N8XGG5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1N8XGG5-1", "url": "https://www.uniprot.org/uniprotkb/A0A1N8XGG5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0X5W1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X5W1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0X5W1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X5W1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XA05", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XA05", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XA05-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XA05-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XD11", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XD11", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XD11-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XD11-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XFP9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFP9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XFP9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFP9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XGJ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XGJ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XGJ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XGJ5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XGL7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XGL7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XGL7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XGL7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P22448", "url": "https://www.uniprot.org/uniprotkb/P22448", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P22448-1", "url": "https://www.uniprot.org/uniprotkb/P22448-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P22448-2", "url": "https://www.uniprot.org/uniprotkb/P22448-2", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTTSSRTCPVPAVNGHMTHYPAAPYPLLFPPVIGGLSLPSLHGLQSHPPTSGCSTPSPATVETQSTSSEELVPSPPSPLPPPRVYKPCFVCQDKSSGYHYGVSACEGCKGFFRRSIQKNMVYTCHRDKNCVINKVTRNRCQYCRLQKCFEVGMSKESVRNDRNKKKKEPTKQESTENYEMTAELDDLTEKIRKAHQETFPSLCQLGKYTTNSSADHRVRLDLGLWDKFSELATKCIIKIVEFAKRLPGFTSLTIADQITLLKAACLDILILRICTRYTPEQDTMTFSDGLTLNRTQMHNAGFGPLTDLVFTFANQLLPLEMDDTETGLLSAICLICGDRQDLEEPMKVDKLQEPLLEALKIYIRKRRPNKPHMFPKILMKITDLRSISAKGAERVITLKMEIPGSMPPLIQEMLENSEGHEPLTPTSNGNTAEHSPSISPSSVDNSSVSQSPMVQ", "length": 455, "header": "sp|P22448-1|RARB_CHICK Isoform 1 of Retinoic acid receptor beta OS=Gallus gallus OX=9031 GN=RARB PE=2 SV=2 CANONICAL=P22448-1" }, "isoforms": [ { "isoform_ac": "A0A1N8XGG5-1", "url": "https://www.uniprot.org/uniprotkb/P22448/entry#A0A1N8XGG5-1", "sequence": { "sequence": "MLDFYTASPSSCMLQEKALKACFSGLAQTEWQHRHSAQSVETQSTSSEELVPSPPSPLPPPRVYKPCFVCQDKSSGYHYGVSACEGCKGFFRRSIQKNMVYTCHRDKNCVINKVTRNRCQYCRLQKCFEVGMSKESVRNDRNKKKKEPTKQESTENYEMTAELDDLTEKIRKAHQETFPSLCQLGKYTTNSSADHRVRLDLGLWDKFSELATKCIIKIVEFAKRLPGFTSLTIADQITLLKAACLDILILRICTRYTPEQDTMTFSDGLTLNRTQMHNAGFGPLTDLVFTFANQLLPLEMDDTETGLLSAICLICGDRQDLEEPMKVDKLQEPLLEALKIYIRKRRPNKPHMFPKILMKITDLRSISAKGAERVITLKMEIPGSMPPLIQEMLENSEGHEPLTPTSNGNTAEHSPSISPSSVDNSSVSQSPMVQ", "length": 434, "header": "tr|A0A1N8XGG5-1|RARB_CHICK Computationally mapped isoform of Retinoic acid receptor beta OS=Gallus gallus OX=9031 GN=RARB PE=2 SV=1 CANONICAL=P22448-1" }, "locus": { "chromosome": "2", "start_pos": 37745151, "end_pos": 37654897, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010005620.1", "url": "https://www.ensembl.org/id/ENSGALT00010005620.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010003459.1", "url": "https://www.ensembl.org/id/ENSGALP00010003459.1" } ] } }, { "isoform_ac": "A0A8V0X5W1-1", "url": "https://www.uniprot.org/uniprotkb/P22448/entry#A0A8V0X5W1-1", "sequence": { "sequence": "MLIPLQFTKPTHSCNITNFVVHEGLQSEAEAVETQSTSSEELVPSPPSPLPPPRVYKPCFVCQDKSSGYHYGVSACEGCKGFFRRSIQKNMVYTCHRDKNCVINKVTRNRCQYCRLQKCFEVGMSKESVRNDRNKKKKEPTKQESTENYEMTAELDDLTEKIRKAHQETFPSLCQLGKYTTNSSADHRVRLDLGLWDKFSELATKCIIKIVEFAKRLPGFTSLTIADQITLLKAACLDILILRICTRYTPEQDTMTFSDGLTLNRTQMHNAGFGPLTDLVFTFANQLLPLEMDDTETGLLSAICLICGDRQDLEEPMKVDKLQEPLLEALKIYIRKRRPNKPHMFPKILMKITDLRSISAKGAERVITLKMEIPGSMPPLIQEMLENSEGHEPLTPTSNGNTAEHSPSISPSSVDNSSVSQSPMVQ", "length": 426, "header": "tr|A0A8V0X5W1-1|RARB_CHICK Computationally mapped isoform of Retinoic acid receptor beta OS=Gallus gallus OX=9031 GN=RARB PE=2 SV=1 CANONICAL=P22448-1" }, "locus": { "chromosome": "2", "start_pos": 37745151, "end_pos": 37657617, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010005616.1", "url": "https://www.ensembl.org/id/ENSGALT00010005616.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010003455.1", "url": "https://www.ensembl.org/id/ENSGALP00010003455.1" } ] } }, { "isoform_ac": "A0A8V0XA05-1", "url": "https://www.uniprot.org/uniprotkb/P22448/entry#A0A8V0XA05-1", "sequence": { "sequence": "MTTSSRTCPVPAVNGHMTHYPAAPYPLLFPPVIGGLSLPSLHGLQSHPPTSGCSTPSPANSWRALNLVWKFDRCVETQSTSSEELVPSPPSPLPPPRVYKPCFVCQDKSSGYHYGVSACEGCKGFFRRSIQKNMVYTCHRDKNCVINKVTRNRCQYCRLQKCFEVGMSKESVRNDRNKKKKEPTKQESTENYEMTAELDDLTEKIRKAHQETFPSLCQLGKYTTNSSADHRVRLDLGLWDKFSELATKCIIKIVEFAKRLPGFTSLTIADQITLLKAACLDILILRICTRYTPEQDTMTFSDGLTLNRTQMHNAGFGPLTDLVFTFANQLLPLEMDDTETGLLSAICLICGDRQDLEEPMKVDKLQEPLLEALKIYIRKRRPNKPHMFPKILMKITDLRSISAKGAERVITLKMEIPGSMPPLIQEMLENSEGHEPLTPTSNGNTAEHSPSISPSSVDNSSVSQSPMVQ", "length": 469, "header": "tr|A0A8V0XA05-1|RARB_CHICK Computationally mapped isoform of Retinoic acid receptor beta OS=Gallus gallus OX=9031 GN=RARB PE=2 SV=1 CANONICAL=P22448-1" }, "locus": { "chromosome": "2", "start_pos": 37745151, "end_pos": 37553066, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010005638.1", "url": "https://www.ensembl.org/id/ENSGALT00010005638.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010003480.1", "url": "https://www.ensembl.org/id/ENSGALP00010003480.1" } ] } }, { "isoform_ac": "A0A8V0XD11-1", "url": "https://www.uniprot.org/uniprotkb/P22448/entry#A0A8V0XD11-1", "sequence": { "sequence": "MTTSSRTCPVPAVNGHMTHYPAAPYPLLFPPVIGGLSLPSLHGLQSHPPTSGCSTPSPATVETQSTSSEELVPSPPSPLPPPRVYKPCFVCQDKSSGYHYGVSACEGCKGFFRRSIQKNMVYTCHRDKNCVINKVTRNRCQYCRLQKCFEVGMSKESVRNDRNKKKKEPTKQESTENYEMTAELDDLTEKIRKAHQETFPSLCQLGKYTTNSSADHRVRLDLGLWDKFSELATKCIIKIVEFAKRLPGFTSLTIADQITLLKAACLDILILRICTRYTPEQDTMTFSDGLTLNRTQMHNAGFGPLTDLVFTFANQLLPLEMDDTETGLLSAICLIYRQDLEEPMKVDKLQEPLLEALKIYIRKRRPNKPHMFPKILMKITDLRSISAKGAERVITLKMEIPGSMPPLIQEMLENSEGHEPLTPTSNGNTAEHSPSISPSSVDNSSVSQSPMVQ", "length": 453, "header": "tr|A0A8V0XD11-1|RARB_CHICK Computationally mapped isoform of Retinoic acid receptor beta OS=Gallus gallus OX=9031 GN=RARB PE=2 SV=1 CANONICAL=P22448-1" }, "locus": { "chromosome": "2", "start_pos": 37745151, "end_pos": 37553066, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010005644.1", "url": "https://www.ensembl.org/id/ENSGALT00010005644.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010003483.1", "url": "https://www.ensembl.org/id/ENSGALP00010003483.1" } ] } }, { "isoform_ac": "A0A8V0XFP9-1", "url": "https://www.uniprot.org/uniprotkb/P22448/entry#A0A8V0XFP9-1", "sequence": { "sequence": "MQKQTNKQTKPKQLERLWGVGLGSSHCLDTGWASLGAVETQSTSSEELVPSPPSPLPPPRVYKPCFVCQDKSSGYHYGVSACEGCKGFFRRSIQKNMVYTCHRDKNCVINKVTRNRCQYCRLQKCFEVGMSKESVRNDRNKKKKEPTKQESTENYEMTAELDDLTEKIRKAHQETFPSLCQLGKYTTNSSADHRVRLDLGLWDKFSELATKCIIKIVEFAKRLPGFTSLTIADQITLLKAACLDILILRICTRYTPEQDTMTFSDGLTLNRTQMHNAGFGPLTDLVFTFANQLLPLEMDDTETGLLSAICLICGDRQDLEEPMKVDKLQEPLLEALKIYIRKRRPNKPHMFPKILMKITDLRSISAKGAERVITLKMEIPGSMPPLIQEMLENSEGHEPLTPTSNGNTAEHSPSISPSSVDNSSVSQSPMVQ", "length": 432, "header": "tr|A0A8V0XFP9-1|RARB_CHICK Computationally mapped isoform of Retinoic acid receptor beta OS=Gallus gallus OX=9031 GN=RARB PE=2 SV=1 CANONICAL=P22448-1" }, "locus": { "chromosome": "2", "start_pos": 37745151, "end_pos": 37606446, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010005631.1", "url": "https://www.ensembl.org/id/ENSGALT00010005631.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010003469.1", "url": "https://www.ensembl.org/id/ENSGALP00010003469.1" } ] } }, { "isoform_ac": "A0A8V0XGJ5-1", "url": "https://www.uniprot.org/uniprotkb/P22448/entry#A0A8V0XGJ5-1", "sequence": { "sequence": "MAKDIRALPRVVVDWKHACLSFPFKVDVQCTHRDPMKFTVETQSTSSEELVPSPPSPLPPPRVYKPCFVCQDKSSGYHYGVSACEGCKGFFRRSIQKNMVYTCHRDKNCVINKVTRNRCQYCRLQKCFEVGMSKESVRNDRNKKKKEPTKQESTENYEMTAELDDLTEKIRKAHQETFPSLCQLGKYTTNSSADHRVRLDLGLWDKFSELATKCIIKIVEFAKRLPGFTSLTIADQITLLKAACLDILILRICTRYTPEQDTMTFSDGLTLNRTQMHNAGFGPLTDLVFTFANQLLPLEMDDTETGLLSAICLICGDRQDLEEPMKVDKLQEPLLEALKIYIRKRRPNKPHMFPKILMKITDLRSISAKGAERVITLKMEIPGSMPPLIQEMLENSEGHEPLTPTSNGNTAEHSPSISPSSVDNSSVSQSPMVQ", "length": 434, "header": "tr|A0A8V0XGJ5-1|RARB_CHICK Computationally mapped isoform of Retinoic acid receptor beta OS=Gallus gallus OX=9031 GN=RARB PE=2 SV=1 CANONICAL=P22448-1" }, "locus": { "chromosome": "2", "start_pos": 37745151, "end_pos": 37677971, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010005612.1", "url": "https://www.ensembl.org/id/ENSGALT00010005612.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010003451.1", "url": "https://www.ensembl.org/id/ENSGALP00010003451.1" } ] } }, { "isoform_ac": "A0A8V0XGL7-1", "url": "https://www.uniprot.org/uniprotkb/P22448/entry#A0A8V0XGL7-1", "sequence": { "sequence": "MTTSSRTCPVPAVNGHMTHYPAAPYPLLFPPVIGGLSLPSLHGLQSHPPTSGCSTPSPATVETQSTSSEELVPSPPSPLPPPRVYKPCFVCQDKSSGYHYGVSACEGCKGFFRRSIQKNMVYTCHRDKNCVINKVTRNRCQYCRLQKCFEVGMSKESVRNDRNKKKKEPTKQESTENYEMTAELDDLTEKIRKAHQETFPSLCQLGKYTTNSSADHRVRLDLGLWDKFSELATKCIIKIVEFAKRLPGFTSLTIADQITLLKAACLDILILRICTRYTPEQDTMTFSDGLTLNRTQMHNAGFGPLTDLVFTFANQLLPLEMDDTETGLLSAICLICGDRQDLEEPMKVDKLQEPLLEALKIYIRKRRPNKPHMFPKILMKITDLRSISAKERVITLKMEIPGSMPPLIQEMLENSEGHEPLTPTSNGNTAEHSPSISPSSVDNSSVSQSPMVQ", "length": 453, "header": "tr|A0A8V0XGL7-1|RARB_CHICK Computationally mapped isoform of Retinoic acid receptor beta OS=Gallus gallus OX=9031 GN=RARB PE=2 SV=1 CANONICAL=P22448-1" }, "locus": { "chromosome": "2", "start_pos": 37745151, "end_pos": 37553066, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010005633.1", "url": "https://www.ensembl.org/id/ENSGALT00010005633.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010003472.1", "url": "https://www.ensembl.org/id/ENSGALP00010003472.1" } ] } }, { "isoform_ac": "P22448-1", "url": "https://www.uniprot.org/uniprotkb/P22448/entry#P22448-1", "sequence": { "sequence": "MTTSSRTCPVPAVNGHMTHYPAAPYPLLFPPVIGGLSLPSLHGLQSHPPTSGCSTPSPATVETQSTSSEELVPSPPSPLPPPRVYKPCFVCQDKSSGYHYGVSACEGCKGFFRRSIQKNMVYTCHRDKNCVINKVTRNRCQYCRLQKCFEVGMSKESVRNDRNKKKKEPTKQESTENYEMTAELDDLTEKIRKAHQETFPSLCQLGKYTTNSSADHRVRLDLGLWDKFSELATKCIIKIVEFAKRLPGFTSLTIADQITLLKAACLDILILRICTRYTPEQDTMTFSDGLTLNRTQMHNAGFGPLTDLVFTFANQLLPLEMDDTETGLLSAICLICGDRQDLEEPMKVDKLQEPLLEALKIYIRKRRPNKPHMFPKILMKITDLRSISAKGAERVITLKMEIPGSMPPLIQEMLENSEGHEPLTPTSNGNTAEHSPSISPSSVDNSSVSQSPMVQ", "length": 455, "header": "sp|P22448-1|RARB_CHICK Isoform 1 of Retinoic acid receptor beta OS=Gallus gallus OX=9031 GN=RARB PE=2 SV=2 CANONICAL=P22448-1" }, "locus": {} }, { "isoform_ac": "P22448-2", "url": "https://www.uniprot.org/uniprotkb/P22448/entry#P22448-2", "sequence": { "sequence": "MFDCMDVLAVSPAQMLDFYTASPSSCMLQEKALKACFSGLAQTEWQHRHSAQSVETQSTSSEELVPSPPSPLPPPRVYKPCFVCQDKSSGYHYGVSACEGCKGFFRRSIQKNMVYTCHRDKNCVINKVTRNRCQYCRLQKCFEVGMSKESVRNDRNKKKKEPTKQESTENYEMTAELDDLTEKIRKAHQETFPSLCQLGKYTTNSSADHRVRLDLGLWDKFSELATKCIIKIVEFAKRLPGFTSLTIADQITLLKAACLDILILRICTRYTPEQDTMTFSDGLTLNRTQMHNAGFGPLTDLVFTFANQLLPLEMDDTETGLLSAICLICGDRQDLEEPMKVDKLQEPLLEALKIYIRKRRPNKPHMFPKILMKITDLRSISAKGAERVITLKMEIPGSMPPLIQEMLENSEGHEPLTPTSNGNTAEHSPSISPSSVDNSSVSQSPMVQ", "length": 448, "header": "sp|P22448-2|RARB_CHICK Isoform 2 of Retinoic acid receptor beta OS=Gallus gallus OX=9031 GN=RARB PE=2 SV=2 CANONICAL=P22448-1" }, "locus": { "chromosome": "2", "start_pos": 37745151, "end_pos": 37654855, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010005624.1", "url": "https://www.ensembl.org/id/ENSGALT00010005624.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010003463.1", "url": "https://www.ensembl.org/id/ENSGALP00010003463.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Isoforms of retinoic acid receptor beta expressed in the chicken embryo.", "journal": "Biochim. Biophys. Acta", "date": "1991", "authors": "Nohno T, Muto K, Noji S, Saito T, Taniguchi S", "evidence": [ { "database": "UniProtKB", "id": "P22448", "url": "https://www.uniprot.org/uniprotkb/P22448" } ], "reference": [ { "type": "PubMed", "id": "1647216", "url": "https://glygen.org/publication/PubMed/1647216" } ] }, { "title": "Retinoic acid treatment alters the distribution of retinoic acid receptor-beta transcripts in the embryonic chick face.", "journal": "Development (Cambridge, England)", "date": "1991-04", "authors": "Rowe A, Richman J M, Brickell P M", "evidence": [ { "database": "UniProtKB", "id": "P22448", "url": "https://www.uniprot.org/uniprotkb/P22448" } ], "reference": [ { "type": "PubMed", "id": "1652423", "url": "https://glygen.org/publication/PubMed/1652423" } ] }, { "title": "Retinoic acid induces polarizing activity but is unlikely to be a morphogen in the chick limb bud.", "journal": "Nature", "date": "1991", "authors": "Noji S, Nohno T, Koyama E, Muto K, Ohyama K, Aoki Y, Tamura K, Ohsugi K, Ide H, Taniguchi S", "evidence": [ { "database": "UniProtKB", "id": "P22448", "url": "https://www.uniprot.org/uniprotkb/P22448" } ], "reference": [ { "type": "PubMed", "id": "1848357", "url": "https://glygen.org/publication/PubMed/1848357" } ] }, { "title": "Nucleotide sequence of an isoform of chicken retinoic acid binding protein-beta varying in its A domain.", "journal": "Nucleic Acids Res.", "date": "1991", "authors": "Padanilam B J, McLeod L B, Suzuki H, Solursh M", "evidence": [ { "database": "UniProtKB", "id": "P22448", "url": "https://www.uniprot.org/uniprotkb/P22448" } ], "reference": [ { "type": "PubMed", "id": "1849630", "url": "https://glygen.org/publication/PubMed/1849630" } ] }, { "title": "Temporal and regional differences in the expression pattern of distinct retinoic acid receptor-beta transcripts in the chick embryo.", "journal": "Development", "date": "1991", "authors": "Smith S M, Eichele G", "evidence": [ { "database": "UniProtKB", "id": "P22448", "url": "https://www.uniprot.org/uniprotkb/P22448" } ], "reference": [ { "type": "PubMed", "id": "1849811", "url": "https://glygen.org/publication/PubMed/1849811" } ] }, { "title": "RAR\u03b2 regulates neuronal cell death and differentiation in the avian ciliary ganglion.", "journal": "Developmental neurobiology", "date": "2015-11", "authors": "Koszinowski Sophie, Boerries Melanie, Busch Hauke, Krieglstein Kerstin", "evidence": [ { "database": "RefSeq", "id": "NP_990657", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990657" } ], "reference": [ { "type": "PubMed", "id": "25663354", "url": "https://glygen.org/publication/PubMed/25663354" } ] }, { "title": "Differential expression of retinoic acid receptor-beta isoforms during chick limb ontogeny.", "journal": "Developmental dynamics : an official publication of the American Association of Anatomists", "date": "1995-01", "authors": "Smith S M, Kirstein I J, Wang Z S, Fallon J F, Kelley J, Bradshaw-Rouse J", "evidence": [ { "database": "UniProtKB", "id": "P22448", "url": "https://www.uniprot.org/uniprotkb/P22448" } ], "reference": [ { "type": "PubMed", "id": "7703521", "url": "https://glygen.org/publication/PubMed/7703521" } ] } ], "pathway": [ { "id": "gga:396266", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:396266", "resource": "KEGG Pathway" }, { "id": "R-GGA-383280", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-383280", "resource": "Reactome", "description": "Nuclear Receptor transcription pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A9J7HD75-1", "protein_name": "Retinoic acid receptor beta", "gene_name": "Rarb", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSTSSHACPVPAVRGHMTHYPAAPYPLLFPPVIGGLSLPPLHGLHGHPPPSGCSTPSPATIETQSTSSEELVPSPPSPLPPPRVYKPCFVCQDKSSGYHYGVSACEGCKGFFRRSIQKNMIYTCHRDKNCVINKVTRNRCQYCRLQKCFEVGMSKESVRNDRNKKKKEPSKQECTESYEMTAELDDLTEKIRKAHQETFPSLCQLGKYTTNSSADHRVRLDLGLWDKFSELATKCIIKIVEFAKRLPGFTGLTIADQITLLKAACLDILILRICTRYTPEQDTMTFSDGLTLNRTQMHNAGFGPLTDLVFTFANQLLPLEMDDTETGLLSAICLICGDRQDLEEPTKVDKLQEPLLEALKIYIRKRRPSKPHMFPKILMKITDLRSISAKGAERVITLKMEIPGSMPPLIQEMLENSEGHEPLTPSSSGNTAEHSPSVSPSSVENSGVSQSPLLQ", "length": 455 }, "evidence": [ { "id": "P22448", "url": "https://omabrowser.org/oma/group/P22448/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0AAA9SMT7-1", "protein_name": "Retinoic acid receptor beta", "gene_name": "RARB", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MFDCMDVLSVSPGRILDFYTASPSSCMLQEKALKACFSGLTQTEWQHRHTAQSIETQSTSSEELVPSPPSPLPPPRVYKPCFVCQDKSSGYHYGVSACEGCKGFFRRSIQKNMIYTCHRDKNCVINKVTRNRCQYCRLQKCFEVGMSKESVRNDRNKKKKEPSKQECTESYEMTAELDDLTEKIRKAHQETFPSLCQLGKYTTNSSADHRVRLDLGLWDKFSELATKCIIKIVEFAKRLPGFTGLTIADQITLLKAACLDILILRICTRYTPEQDTMTFSDGLTLNRTQMHNAGFGPLTDLVFTFAGQLLPLEMDDAETGLLSAICLICGDRQDLEEPTKVDKLQEPLLEALKIYIRKRRPSKPHMFPKILMKITDLRSISAKGAERVITLKMEIPGSMPPLIQEMLENSEGHEPLTPSSGGHTAEPSPSVSPSSVEHSGVGQSPLLQ", "length": 448 }, "evidence": [ { "id": "P22448", "url": "https://omabrowser.org/oma/group/P22448/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P10826-1", "protein_name": "Retinoic acid receptor beta", "gene_name": "RARB", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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"https://www.uniprot.org/uniprotkb/P22448" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "P22448", "url": "https://www.uniprot.org/uniprotkb/P22448" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "P22448", "url": "https://www.uniprot.org/uniprotkb/P22448" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "P22448", "url": "https://www.uniprot.org/uniprotkb/P22448" } ], "pmid": "" }, { "name": "response to retinoic acid", "id": "GO:0032526", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032526", "evidence": [ { "database": "UniProtKB", "id": "P22448", "url": "https://www.uniprot.org/uniprotkb/P22448" } ], "pmid": "" }, { "name": "retinoic acid receptor signaling pathway", "id": "GO:0048384", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048384", "evidence": [ { "database": "UniProtKB", "id": "P22448", "url": "https://www.uniprot.org/uniprotkb/P22448" } ], "pmid": "" }, { "name": "limb morphogenesis", "id": "GO:0035108", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035108", "evidence": [ { "database": "UniProtKB", "id": "P22448", "url": "https://www.uniprot.org/uniprotkb/P22448" } ], "pmid": "" }, { "name": "inner ear receptor cell differentiation involved in inner ear sensory epithelium regeneration", "id": "GO:0070660", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070660", "evidence": [ { "database": "UniProtKB", "id": "P22448", "url": "https://www.uniprot.org/uniprotkb/P22448" } ], "pmid": "" }, { "name": "beak morphogenesis", "id": "GO:0071729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071729", "evidence": [ { "database": "UniProtKB", "id": "P22448", "url": "https://www.uniprot.org/uniprotkb/P22448" } ], "pmid": "" }, { "name": "anatomical structure morphogenesis", "id": "GO:0009653", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009653", "evidence": [ { "database": "UniProtKB", "id": "P22448", "url": "https://www.uniprot.org/uniprotkb/P22448" } ], "pmid": "" }, { "name": "embryonic digestive tract development", "id": "GO:0048566", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048566", "evidence": [ { "database": "UniProtKB", "id": "P22448", "url": "https://www.uniprot.org/uniprotkb/P22448" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P22448", "url": "https://www.uniprot.org/uniprotkb/P22448" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "P22448", "url": "https://www.uniprot.org/uniprotkb/P22448" } ], "pmid": "" }, { "name": "RNA polymerase II transcription regulator complex", "id": "GO:0090575", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090575", "evidence": [ { "database": "UniProtKB", "id": "P22448", "url": "https://www.uniprot.org/uniprotkb/P22448" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "P22448", "url": "https://www.uniprot.org/uniprotkb/P22448" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "P22448", "url": "https://www.uniprot.org/uniprotkb/P22448" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "P22448", "url": "https://www.uniprot.org/uniprotkb/P22448" } ], "pmid": "" }, { "name": "nuclear receptor activity", "id": "GO:0004879", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004879", "evidence": [ { "database": "UniProtKB", "id": "P22448", "url": "https://www.uniprot.org/uniprotkb/P22448" } ], "pmid": "" }, { "name": "sequence-specific DNA binding", "id": "GO:0043565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043565", "evidence": [ { "database": "UniProtKB", "id": "P22448", "url": "https://www.uniprot.org/uniprotkb/P22448" } ], "pmid": "" }, { "name": "sequence-specific double-stranded DNA binding", "id": "GO:1990837", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990837", "evidence": [ { "database": "UniProtKB", "id": "P22448", "url": "https://www.uniprot.org/uniprotkb/P22448" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 211, "end_pos": 213, "annotation": "n_glycosylation_sequon" }, { "start_pos": 293, "end_pos": 295, "annotation": "n_glycosylation_sequon" }, { "start_pos": 445, "end_pos": 447, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-P22448-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 455, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-P22448-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/P22448" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "P22448", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P22448" }, { "id": "PRU01189", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU01189" } ], "ann_type": 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Required to facilitate mitochondrial and nuclear replication fork progression by initiating de novo DNA synthesis using dNTPs and acting as an error-prone DNA polymerase able to bypass certain DNA lesions (PubMed:26694751, PubMed:27230014). Shows a high capacity to tolerate DNA damage lesions such as 8oxoG and abasic sites in DNA (By similarity). Provides different translesion synthesis alternatives when DNA replication is stalled: able to synthesize DNA primers downstream of lesions, such as UV lesions, R-loops and G-quadruplexes, to allow DNA replication to continue (PubMed:26626482, PubMed:26694751, PubMed:27230014). Can also realign primers ahead of 'unreadable lesions' such as abasic sites and 6-4 photoproduct (6-4 pyrimidine-pyrimidinone), thereby skipping the lesion. Repriming avoids fork degradation while leading to accumulation of internal ssDNA gaps behind the forks (By similarity). Also able to incorporate nucleotides opposite DNA lesions such as 8oxoG, like a regular translesion synthesis DNA polymerase (By similarity). Also required for reinitiating stalled forks after ultraviolet (UV) damage during nuclear DNA replication (By similarity). Required for mitochondrial DNA (mtDNA) synthesis and replication, by reinitiating synthesis after UV damage or in the presence of chain-terminating nucleotides (By similarity). In addition to its role in DNA damage response, also required to maintain efficient nuclear and mitochondrial DNA replication in unperturbed cells (By similarity).", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TTB3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TTB3#function" }, { "database": "PubMed", "id": "26694751", "url": "https://glygen.org/publication/PubMed/26694751" }, { "database": "PubMed", "id": "27230014", "url": "https://glygen.org/publication/PubMed/27230014" }, { "database": "PubMed", "id": "26626482", "url": "https://glygen.org/publication/PubMed/26626482" }, { "database": "UniProtKB", "id": "Q96LW4", "url": "https://www.uniprot.org/uniprotkb/Q96LW4#function" }, { "database": "PubMed", "id": "30478192", "url": "https://glygen.org/publication/PubMed/30478192" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TTB3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TTB3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PRIMPOL", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TTB3", "locus": { "chromosome": "4", "start_pos": 39055943, "end_pos": 39072577, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010007085", "url": "https://www.ensembl.org/id/ENSGALG00010007085" } ] } } ], "crossref": [ { "id": "A0A3Q2TTB3", "url": "https://alphafold.ebi.ac.uk/entry/A0A3Q2TTB3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000010636", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000010636", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd22256", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22256", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR044917", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044917", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2TTB3", "url": "https://www.orthodb.org/?gene=A0A3Q2TTB3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31399", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31399", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31399:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31399:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03121", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03121", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:A0A3Q2TTB3", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:A0A3Q2TTB3", "database": "PRO", "categories": [ "Protein" ] }, { "id": "22508", "url": "https://www.rhea-db.org/rhea/22508", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q2TTB3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TTB3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2TTB3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TTB3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2TTB3-2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TTB3-2", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKRKWEERVKKVEELASYYERNPLPTVYKPRLSKPLQPSRVWKIFCRQADAFRFVKTCKEDVHVFALERNTQNGQRFYLVTTYQELWYYYTKGYKTSLMHCYEVIPEKDACKLYFDLEFYKAANPGADGKDMVAKLIELVSQKLKELYDVNCSARDVLNLDSSTDEKFSRHLIFLPCKTVFKDNIHVGNFVRTILQPAIRLVGSNVAAPIAEGGAGYTSQCSAPTVELDGPLTNLTAVEDASKGWPAIADQRKETETSHHGENSEFSFLIVNNKEGDKQLFVDLGVYTRNRNFRMYKSSKAGKNVILTIAEDNKFVPNCEENVSLEEAYFLSSLVCNVRFEDGTKILSSNFVEEEIKMSAFLRSKTTRSTREPMEGYQESPYPEIDCFVRSLINKDGVQGGIRQWNYFSGEEILVYDISGYRWCENIGRAHRSNNIMILVDLKKEVWYQKCHDPVCREKNFKSQSLPLPSRICLSSLFIEEEDHMVTDERENTEVTSHSNPADLSESSAYLAINTSQDTQWDNASDDAYLVETAEDVELAEAADYSLGYDTEEIPDEVLLEMSWKQDTCSKDDS", "length": 574, "header": "sp|A0A3Q2TTB3-1|PRIPO_CHICK Isoform 1 of DNA-directed primase/polymerase protein OS=Gallus gallus OX=9031 GN=PRIMPOL PE=1 SV=1 CANONICAL=A0A3Q2TTB3-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2TTB3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TTB3/entry#A0A3Q2TTB3-1", "sequence": { "sequence": "MKRKWEERVKKVEELASYYERNPLPTVYKPRLSKPLQPSRVWKIFCRQADAFRFVKTCKEDVHVFALERNTQNGQRFYLVTTYQELWYYYTKGYKTSLMHCYEVIPEKDACKLYFDLEFYKAANPGADGKDMVAKLIELVSQKLKELYDVNCSARDVLNLDSSTDEKFSRHLIFLPCKTVFKDNIHVGNFVRTILQPAIRLVGSNVAAPIAEGGAGYTSQCSAPTVELDGPLTNLTAVEDASKGWPAIADQRKETETSHHGENSEFSFLIVNNKEGDKQLFVDLGVYTRNRNFRMYKSSKAGKNVILTIAEDNKFVPNCEENVSLEEAYFLSSLVCNVRFEDGTKILSSNFVEEEIKMSAFLRSKTTRSTREPMEGYQESPYPEIDCFVRSLINKDGVQGGIRQWNYFSGEEILVYDISGYRWCENIGRAHRSNNIMILVDLKKEVWYQKCHDPVCREKNFKSQSLPLPSRICLSSLFIEEEDHMVTDERENTEVTSHSNPADLSESSAYLAINTSQDTQWDNASDDAYLVETAEDVELAEAADYSLGYDTEEIPDEVLLEMSWKQDTCSKDDS", "length": 574, "header": "sp|A0A3Q2TTB3-1|PRIPO_CHICK Isoform 1 of DNA-directed primase/polymerase protein OS=Gallus gallus OX=9031 GN=PRIMPOL PE=1 SV=1 CANONICAL=A0A3Q2TTB3-1" }, "locus": {} }, { "isoform_ac": "A0A3Q2TTB3-2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TTB3/entry#A0A3Q2TTB3-2", "sequence": { "sequence": "MKRKWEERVKKVEELASYYERNPLPTVYKPRLSKPLQPSRVWKIFCRQADAFRFVKTCKEDVHVFALERNTQNGQRFYLVTTYQELWYYYTKGYKTSLMHCYEVIPEKDACKLYFDLEFYKAANPGADGKDMVAKLIELVSQKLKELYDVNCSARDVLNLDSSTDEKFSRHLIFLPCKTVFKDNIHVGNFVRTILQPAIRLVGSNVAAPIAEGGAGYTSQCSAPTVELDGPLTNLTAVEDASKGWPAIADQRKETETSHHGENSEFSFLIVNNKEGDKQLFVDLGVYTRNRNFRMYKSSKAGKNVILTIAEDNKFVPNCEENVSLEEAYFLSSLVCNVRFEDGTKILSSNFVEEEIKMSAFLRSKTTRSTRGIRQWNYFSGEEILVYDISGYRWCENIGRAHRSNNIMILVDLKKEVWYQKCHDPVCREKNFKSQSLPLPSRICLSSLFIEEEDHMVTDERENTEVTSHSNPADLSESSAYLAINTSQDTQWDNASDDAYLVETAEDVELAEAADYSLGYDTEEIPDEVLLEMSWKQDTCSKDDS", "length": 545, "header": "sp|A0A3Q2TTB3-2|PRIPO_CHICK Isoform 2 of DNA-directed primase/polymerase protein OS=Gallus gallus OX=9031 GN=PRIMPOL PE=1 SV=1 CANONICAL=A0A3Q2TTB3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "Sequence and comparative analysis of the chicken genome provide unique perspectives on vertebrate evolution.", "journal": "Nature", "date": "2004", "authors": "", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TTB3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TTB3" } ], "reference": [ { "type": "PubMed", "id": "15592404", "url": "https://glygen.org/publication/PubMed/15592404" } ] }, { "title": "PrimPol Is Required for Replicative Tolerance of G Quadruplexes in Vertebrate Cells.", "journal": "Molecular cell", "date": "2016", "authors": "Schiavone D, Jozwiakowski SK, Romanello M, Guilbaud G, Guilliam TA, Bailey LJ, Sale JE, Doherty AJ", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TTB3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TTB3" } ], "reference": [ { "type": "PubMed", "id": "26626482", "url": "https://glygen.org/publication/PubMed/26626482" } ] }, { "title": "PrimPol-deficient cells exhibit a pronounced G2 checkpoint response following UV damage.", "journal": "Cell cycle (Georgetown, Tex.)", "date": "2016", "authors": "Bailey Laura J, Bianchi Julie, H\u00e9garat Nadia, Hochegger Helfrid, Doherty Aidan J", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TTB3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TTB3" } ], "reference": [ { "type": "PubMed", "id": "26694751", "url": "https://glygen.org/publication/PubMed/26694751" } ] }, { "title": "Repriming by PrimPol is critical for DNA replication restart downstream of lesions and chain-terminating nucleosides.", "journal": "Cell cycle (Georgetown, Tex.)", "date": "2016-08-02", "authors": "Kobayashi Kaori, Guilliam Thomas A, Tsuda Masataka, Yamamoto Junpei, Bailey Laura J, Iwai Shigenori, Takeda Shunichi, Doherty Aidan J, Hirota Kouji", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TTB3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TTB3" } ], "reference": [ { "type": "PubMed", "id": "27230014", "url": "https://glygen.org/publication/PubMed/27230014" } ] }, { "title": "R-loop formation during S phase is restricted by PrimPol-mediated repriming.", "journal": "The EMBO journal", "date": "2019", "authors": "Svikovic S, Crisp A, Tan-Wong SM, Guilliam TA, Doherty AJ, Proudfoot NJ, Guilbaud G, Sale JE", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TTB3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TTB3" } ], "reference": [ { "type": "PubMed", "id": "30478192", "url": "https://glygen.org/publication/PubMed/30478192" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "DNA-directed DNA polymerase activity", "id": "GO:0003887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003887", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TTB3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TTB3" } ], "pmid": "" }, { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TTB3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TTB3" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TTB3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TTB3" } ], "pmid": "" }, { "name": "manganese ion binding", "id": "GO:0030145", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030145", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TTB3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TTB3" } ], "pmid": "" }, { "name": "DNA-directed RNA polymerase activity", "id": "GO:0003899", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003899", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TTB3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TTB3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TTB3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TTB3" } ], "pmid": "" }, { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TTB3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TTB3" } ], "pmid": "" }, { "name": "replication fork", "id": "GO:0005657", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005657", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TTB3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TTB3" } ], "pmid": "" }, { "name": "DNA-directed RNA polymerase complex", "id": "GO:0000428", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000428", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TTB3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TTB3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "response to UV", "id": "GO:0009411", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009411", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TTB3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TTB3" } ], "pmid": "" }, { "name": "translesion synthesis", "id": "GO:0019985", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019985", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TTB3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TTB3" } ], "pmid": "" }, { "name": "mitochondrial DNA replication", "id": "GO:0006264", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006264", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TTB3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TTB3" } ], "pmid": "" }, { "name": "mitochondrial DNA repair", "id": "GO:0043504", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043504", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TTB3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TTB3" } ], "pmid": "" }, { "name": "error-prone translesion synthesis", "id": "GO:0042276", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042276", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TTB3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TTB3" } ], "pmid": "" }, { "name": "replication fork processing", "id": "GO:0031297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031297", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TTB3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TTB3" } ], "pmid": "" }, { "name": "R-loop processing", "id": "GO:0062176", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0062176", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TTB3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TTB3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 151, "end_pos": 153, "annotation": "n_glycosylation_sequon" }, { "start_pos": 234, "end_pos": 236, "annotation": "n_glycosylation_sequon" }, { "start_pos": 322, "end_pos": 324, "annotation": "n_glycosylation_sequon" }, { "start_pos": 514, "end_pos": 516, "annotation": "n_glycosylation_sequon" }, { "start_pos": 523, "end_pos": 525, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "22508", "name": "", "equation": "DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0Z8P6-1", "A0A8V0XWC6-1", "Q92076-1", "A0A8V0ZUF2-1", "A0A8V0ZBR9-1", "P36195-1", "A0A8V0X4G3-1", "A0A8V0X331-1", "P10399-1", "A0A8V1A4V3-1", "A0A3Q2TTB3-1", "A0A8V0YNB2-1", "A0A8V0XWS0-1", "A0A8V0Y2U3-1", "A0A8V0Z9E4-1" ], "evidence": [ { "id": "22508", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/22508" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q2TTB3", "gene_name": "PRIMPOL", "activity": [ { "ec_number": "2.7.7.7", "activity": "DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate.", "evidence": [ { "id": "A0A3Q2TTB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TTB3" } ] }, { "ec_number": "2.7.7.102", "activity": "ssDNA + n dNTP = ssDNA/pppdN(pdN)n-1 hybrid + (n-1) diphosphate.", "evidence": [ { "id": "A0A3Q2TTB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TTB3" } ] }, { "ec_number": "2.7.7.102", "activity": "", "evidence": [ { "id": "A0A3Q2TTB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TTB3" } ] }, { "ec_number": "2.7.7.7", "activity": "", "evidence": [ { "id": "A0A3Q2TTB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TTB3" } ] } ] }, { "uniprot_ac": "A0A8V0X331", "gene_name": "POLD1", "activity": [ { "ec_number": "2.7.7.7", "activity": "DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate.", "evidence": [ { "id": "A0A8V0X331", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X331" } ] }, { "ec_number": "2.7.7.7", "activity": "", "evidence": [ { "id": "A0A8V0X331", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X331" } ] } ] }, { "uniprot_ac": "A0A8V0X4G3", "gene_name": "POLA1", "activity": [ { "ec_number": "2.7.7.7", "activity": "DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate.", "evidence": [ { "id": "A0A8V0X4G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X4G3" } ] }, { "ec_number": "2.7.7.7", "activity": "", "evidence": [ { "id": "A0A8V0X4G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X4G3" } ] } ] }, { "uniprot_ac": "A0A8V0XWC6", "gene_name": "TERT", "activity": [ { "ec_number": "2.7.7.49", "activity": "DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate.", "evidence": [ { "id": "A0A8V0XWC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XWC6" } ] }, { "ec_number": "2.7.7.49", "activity": "", "evidence": [ { "id": "A0A8V0XWC6", "database": "UniProtKB", "url": 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introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000341.1. On Nov 5, 2021 this sequence version replaced NP_990507.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_990507", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990507" } ] }, { "annotation": "Data demonstrate that peripapillary glial cells express alphaB-crystallin, which is not expressed in Muller cells, during retinal development.", "evidence": [ { "database": "RefSeq", "id": "NP_990507", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990507" }, { "database": "PubMed", "id": "20872245", "url": "https://glygen.org/publication/PubMed/20872245" } ] }, { "annotation": "ELISAs indicated aspirin (ASA) induced CryAB in vivo to protect against heat stress-induced myocardial damage, but ASA did not induce CryAB in primary chicken myocardial cells. Publication Status: Online-Only", "evidence": [ { "database": "RefSeq", "id": "NP_990507", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990507" }, { "database": "PubMed", "id": "27857180", "url": "https://glygen.org/publication/PubMed/27857180" } ] }, { "annotation": "May contribute to the transparency and refractive index of the lens.", "evidence": [ { "database": "UniProtKB", "id": "Q05713", "url": "https://www.uniprot.org/uniprotkb/Q05713#function" }, { "database": "UniProtKB", "id": "A0A3Q2TTM1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TTM1#function" }, { "database": "UniProtKB", "id": "ARBA00053850", "url": "https://www.uniprot.org/uniprotkb/ARBA00053850#function" }, { "database": "UniProtKB", "id": "A0A8V1A6F3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6F3#function" } ] }, { "annotation": "No significant changes in retinal cryab RNA transcript expression were seen in response to plus lenses compared to either contralateral control values", "evidence": [ { "database": "RefSeq", "id": "NP_990507", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990507" }, { "database": "PubMed", "id": "19878675", "url": "https://glygen.org/publication/PubMed/19878675" } ] }, { "annotation": "These results suggest that HSPB1 protein forms complexes with alphaB-crystallin in aged chicken muscle and suppose to become the candidate of age-related bio-marker for verifying the age of chicken meat.", "evidence": [ { "database": "RefSeq", "id": "NP_990507", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990507" }, { "database": "PubMed", "id": "26139560", "url": "https://glygen.org/publication/PubMed/26139560" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q05713", "url": "https://www.uniprot.org/uniprotkb/Q05713" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CRYAB", "url": "https://www.uniprot.org/uniprotkb/Q05713", "locus": { "chromosome": "24", "start_pos": 6273112, "end_pos": 6257233, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010025192", "url": "https://www.ensembl.org/id/ENSGALG00010025192" } ] } } ], "crossref": [ { "id": "Q05713", "url": "https://alphafold.ebi.ac.uk/entry/Q05713", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000007945", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000007945", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd06498", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06498", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "396089", "url": "https://www.ncbi.nlm.nih.gov/gene/396089", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001436", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001436", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002068", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002068", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003090", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003090", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008978", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008978", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037882", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037882", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055269", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055269", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:396089", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:396089", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FRDWWED", "url": 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Classification", "Other" ] }, { "id": "PF00525", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00525", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q05713", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q05713", "database": "PRO", "categories": [ "Protein" ] }, { "id": "R-GGA-3371571", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3371571", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_990507", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990507", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q2TTM1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TTM1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2TTM1-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TTM1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A6F3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6F3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A6F3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6F3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q05713", "url": "https://www.uniprot.org/uniprotkb/Q05713", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q05713-1", "url": "https://www.uniprot.org/uniprotkb/Q05713-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDITIHNPLIRRPLFSWLTPSRIFDQIFGEHLQESELLPTSPSLSPFLMRSPFFRMPSWLETGLSEMRLEKDKFSVNLDVKHFSPEELKVKVLGDMIEIHGKHEERQDEHGFIAREFSRKYRIPADVDPLTITSSLSLDGVLTVSAPRKQSDVPERSIPITREEKPAIAGSQRK", "length": 174, "header": "sp|Q05713-1|CRYAB_CHICK Isoform 1 of Alpha-crystallin B chain OS=Gallus gallus OX=9031 GN=CRYAB PE=2 SV=2 CANONICAL=Q05713-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2TTM1-1", "url": "https://www.uniprot.org/uniprotkb/Q05713/entry#A0A3Q2TTM1-1", "sequence": { "sequence": "MEMSTGICPAQPQPLWGVREIFGEHLQESELLPTSPSLSPFLMRSPFFRMPSWLETGLSEMRLEKDKFSVNLDVKHFSPEELKVKVLGDMIEIHGKHEERQDEHGFIAREFSRKYRIPADVDPLTITSSLSLDGVLTVSAPRKQSDVPERSIPITREEKPAIAGSQRK", "length": 168, "header": "tr|A0A3Q2TTM1-1|A0A3Q2TTM1_CHICK Computationally mapped isoform of Alpha-crystallin B chain OS=Gallus gallus OX=9031 GN=CRYAB PE=1 SV=1 CANONICAL=Q05713-1" }, "locus": { "chromosome": "24", "start_pos": 6272418, "end_pos": 6266971, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010061471.1", "url": "https://www.ensembl.org/id/ENSGALT00010061471.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010037977.1", "url": "https://www.ensembl.org/id/ENSGALP00010037977.1" } ] } }, { "isoform_ac": "A0A8V1A6F3-1", "url": "https://www.uniprot.org/uniprotkb/Q05713/entry#A0A8V1A6F3-1", "sequence": { "sequence": "MRSPFFRMPSWLETGLSEMRLEKDKFSVNLDVKHFSPEELKVKVLGDMIEIHGKHEERQDEHGFIAREFSRKYRIPADVDPLTITSSLSLDGVLTVSAPRKQSDVPERSIPITREEKPAIAGSQRK", "length": 126, "header": "tr|A0A8V1A6F3-1|CRYAB_CHICK Computationally mapped isoform of Alpha-crystallin B chain OS=Gallus gallus OX=9031 GN=CRYAB PE=2 SV=1 CANONICAL=Q05713-1" }, "locus": { "chromosome": "24", "start_pos": 6272418, "end_pos": 6269340, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010061482.1", "url": "https://www.ensembl.org/id/ENSGALT00010061482.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010037980.1", "url": "https://www.ensembl.org/id/ENSGALP00010037980.1" } ] } }, { "isoform_ac": "Q05713-1", "url": "https://www.uniprot.org/uniprotkb/Q05713/entry#Q05713-1", "sequence": { "sequence": "MDITIHNPLIRRPLFSWLTPSRIFDQIFGEHLQESELLPTSPSLSPFLMRSPFFRMPSWLETGLSEMRLEKDKFSVNLDVKHFSPEELKVKVLGDMIEIHGKHEERQDEHGFIAREFSRKYRIPADVDPLTITSSLSLDGVLTVSAPRKQSDVPERSIPITREEKPAIAGSQRK", "length": 174, "header": "sp|Q05713-1|CRYAB_CHICK Isoform 1 of Alpha-crystallin B chain OS=Gallus gallus OX=9031 GN=CRYAB PE=2 SV=2 CANONICAL=Q05713-1" }, "locus": { "chromosome": "24", "start_pos": 6272418, "end_pos": 6269196, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010061460.1", "url": "https://www.ensembl.org/id/ENSGALT00010061460.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010037973.1", "url": "https://www.ensembl.org/id/ENSGALP00010037973.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Crystallin gene expression in the process of lentoidogenesis in cultures of chicken lens epithelial cells.", "journal": "Exp. Eye Res.", "date": "1992", "authors": "Sawada K, Agata K, Eguchi G", "evidence": [ { "database": "UniProtKB", "id": "Q05713", "url": "https://www.uniprot.org/uniprotkb/Q05713" } ], "reference": [ { "type": "PubMed", "id": "1283129", "url": "https://glygen.org/publication/PubMed/1283129" } ] }, { "title": "Changes in retinal alphaB-crystallin (cryab) RNA transcript levels during periods of altered ocular growth in chickens.", "journal": "Experimental eye research", "date": "2010-02", "authors": "Ashby Regan S, Megaw Pam L, Morgan Ian G", "evidence": [ { "database": "RefSeq", "id": "NP_990507", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990507" } ], "reference": [ { "type": "PubMed", "id": "19878675", "url": "https://glygen.org/publication/PubMed/19878675" } ] }, { "title": "Expression of \u03b1B-crystallin in the peripapillary glial cells of the developing chick retina.", "journal": "Neurochemical research", "date": "2011-01", "authors": "Kim Ji Young, Sohn Hyun Joon, Lee Eun Young, Goo Yong Sook, Kim Dong Woon, Seo Je Hoon", "evidence": [ { "database": "RefSeq", "id": "NP_990507", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990507" } ], "reference": [ { "type": "PubMed", "id": "20872245", "url": "https://glygen.org/publication/PubMed/20872245" } ] }, { "title": "Chicken heat shock protein HSPB1 increases and interacts with \u03b1B-crystallin in aged skeletal muscle.", "journal": "Bioscience, biotechnology, and biochemistry", "date": "2015", "authors": "Ueda Shuji, Kokaji Yoshito, Simizu Shunsaku, Honda Kazuhisa, Yoshino Ken-ichi, Kamisoyama Hiroshi, Shirai Yasuhito, Yamanoue Minoru", "evidence": [ { "database": "RefSeq", "id": "NP_990507", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990507" } ], "reference": [ { "type": "PubMed", "id": "26139560", "url": "https://glygen.org/publication/PubMed/26139560" } ] }, { "title": "Aspirin upregulates \u03b1B-Crystallin to protect the myocardium against heat stress in broiler chickens.", "journal": 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"sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A3Q2U125-1", "uniprot_ac": "A0A3Q2U125", "uniprot_id": "A0A3Q2U125_CHICK", "mass": { "chemical_mass": 11970.0, "monoisotopic_mass": 11970.0 }, "refseq": { "ac": "XP_003643029", "name": "C-C motif chemokine 26", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003643029" }, "gene_names": [ { "name": "LOC100857191", "type": "recommended", "evidence": [ { "id": "A0A3Q2U125", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U125" } ] }, { "name": "LOC100857191", "type": "synonym", "evidence": [ { "id": "XP_003643029", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003643029" } ] } ], "protein_names": [ { "name": "C-C motif chemokine", "type": "recommended", "evidence": [ { "id": "A0A3Q2U125", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U125/entry#names_and_taxonomy" } ] }, { "name": "C-C motif chemokine 26", 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This record is derived from a genomic sequence (NC_052572.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003643029", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003643029" } ] }, { "annotation": "Chemokine, which displays chemotactic activity for T lymphocytes, preferentially Th2 cells, but not monocytes or granulocytes. Therefore plays an important role in a wide range of inflammatory and immunological processes. Acts by binding to CCR4 at T-cell surface. Mediates GM-CSF/CSF2-driven pain and inflammation. In the brain, required to maintain the typical, highly branched morphology of hippocampal microglia under homeostatic conditions. May be important for the appropriate adaptation of microglial morphology and synaptic plasticity to acute lipopolysaccharide (LPS)-induced neuroinflammation. 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"count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YJP6-1", "uniprot_ac": "A0A8V0YJP6", "uniprot_id": "A0A8V0YJP6_CHICK", "mass": { "chemical_mass": 55106.0, "monoisotopic_mass": 55106.0 }, "refseq": { "ac": "XP_040512452", "name": "alanine--glyoxylate aminotransferase 2, mitochondrial isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040512452" }, "gene_names": [ { "name": "AGXT2", "type": "recommended", "evidence": [ { "id": "A0A8V0YJP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP6" } ] }, { "name": "AGXT2", "type": "synonym", "evidence": [ { "id": "XP_040512452", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040512452" } ] } ], "protein_names": [ { "name": "Alanine--glyoxylate aminotransferase 2, mitochondrial", "type": "recommended", "evidence": [ { "id": "A0A8V0YJP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP6/entry#names_and_taxonomy" } ] }, { "name": "(R)-3-amino-2-methylpropionate--pyruvate transaminase", "type": "synonym", "evidence": [ { "id": "A0A8V0YJP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP6/entry#names_and_taxonomy" } ] }, { "name": "2.6.1.18", "type": "synonym", "evidence": [ { "id": "A0A8V0YJP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP6/entry#names_and_taxonomy" } ] }, { "name": "2.6.1.40", "type": "synonym", "evidence": [ { "id": "A0A8V0YJP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP6/entry#names_and_taxonomy" } ] }, { "name": "2.6.1.44", "type": "synonym", "evidence": [ { "id": "A0A8V0YJP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP6/entry#names_and_taxonomy" } ] }, { "name": "Beta-ALAAT II", "type": "synonym", "evidence": [ { "id": "A0A8V0YJP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP6/entry#names_and_taxonomy" } ] }, { "name": "Beta-alanine-pyruvate aminotransferase", "type": "synonym", "evidence": [ { "id": "A0A8V0YJP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP6/entry#names_and_taxonomy" } ] }, { "name": "D-3-aminoisobutyrate-pyruvate aminotransferase", "type": "synonym", "evidence": [ { "id": "A0A8V0YJP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP6/entry#names_and_taxonomy" } ] }, { "name": "D-AIBAT", "type": "synonym", "evidence": [ { "id": "A0A8V0YJP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP6/entry#names_and_taxonomy" } ] }, { "name": "D-beta-aminoisobutyrate-pyruvate aminotransferase", "type": "synonym", "evidence": [ { "id": "A0A8V0YJP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP6/entry#names_and_taxonomy" } ] }, { "name": "alanine--glyoxylate aminotransferase 2, mitochondrial isoform X1", "type": "synonym", "evidence": [ { "id": "XP_040512452", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040512452" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052572.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040512452", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040512452" } ] }, { "annotation": "Multifunctional aminotransferase with a broad substrate specificity. Catalyzes the conversion of glyoxylate to glycine using alanine as the amino donor. Catalyzes metabolism of not L- but the D-isomer of D-beta-aminoisobutyric acid to generate 2-methyl-3-oxopropanoate and alanine. Catalyzes the transfer of the amino group from beta-alanine to pyruvate to yield L-alanine and 3-oxopropanoate. Can metabolize NG-monomethyl-L-arginine (NMMA), asymmetric NG,NG-dimethyl-L-arginine (ADMA) and symmetric NG,N'G-dimethyl-L-arginine (SDMA). ADMA is a potent inhibitor of nitric-oxide (NO) synthase, and this activity provides mechanism through which the kidney regulates blood pressure.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJP6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP6#function" }, { "database": "UniProtKB", "id": "ARBA00058068", "url": "https://www.uniprot.org/uniprotkb/ARBA00058068#function" }, { "database": "UniProtKB", "id": "A0A3Q2U2I2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U2I2#function" }, { "database": "UniProtKB", "id": "A0A8V0YLK8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLK8#function" }, { "database": "UniProtKB", "id": "A0A8V0YLL2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLL2#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJP6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "AGXT2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP6", "locus": { "chromosome": "Z", "start_pos": 11137780, "end_pos": 11152914, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013296", "url": "https://www.ensembl.org/id/ENSGALG00010013296" } ] } } ], "crossref": [ { "id": "A0A8V0YJP6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YJP6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000003432", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000003432", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00610", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00610", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "431666", "url": "https://www.ncbi.nlm.nih.gov/gene/431666", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR005814", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005814", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015421", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015421", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015422", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015422", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015424", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015424", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049704", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049704", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:431666", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:431666", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ERDNICQ", "url": "https://omabrowser.org/oma/group/ERDNICQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2U2I2", "url": "https://www.orthodb.org/?gene=A0A3Q2U2I2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YJP6", "url": "https://www.orthodb.org/?gene=A0A8V0YJP6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YLK8", "url": "https://www.orthodb.org/?gene=A0A8V0YLK8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YLL2", "url": "https://www.orthodb.org/?gene=A0A8V0YLL2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45688", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45688", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45688:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45688:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00202", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00202", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-389661", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-389661", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_040512452", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040512452", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "14077", "url": "https://www.rhea-db.org/rhea/14077", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "18393", "url": "https://www.rhea-db.org/rhea/18393", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "24248", "url": "https://www.rhea-db.org/rhea/24248", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "77303", "url": "https://www.rhea-db.org/rhea/77303", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "77307", "url": "https://www.rhea-db.org/rhea/77307", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "77311", "url": "https://www.rhea-db.org/rhea/77311", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "77315", "url": "https://www.rhea-db.org/rhea/77315", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "77319", "url": "https://www.rhea-db.org/rhea/77319", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "77323", "url": "https://www.rhea-db.org/rhea/77323", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "77327", "url": "https://www.rhea-db.org/rhea/77327", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "77331", "url": "https://www.rhea-db.org/rhea/77331", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "77339", "url": "https://www.rhea-db.org/rhea/77339", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "77343", "url": "https://www.rhea-db.org/rhea/77343", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "77347", "url": "https://www.rhea-db.org/rhea/77347", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "77351", "url": "https://www.rhea-db.org/rhea/77351", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "77355", "url": "https://www.rhea-db.org/rhea/77355", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "77359", "url": "https://www.rhea-db.org/rhea/77359", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "77363", "url": "https://www.rhea-db.org/rhea/77363", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q2U2I2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U2I2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2U2I2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U2I2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJP6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJP6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLK8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLK8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLK8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLK8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLL2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLL2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLL2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLL2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAGGLGRGGQLGGVVFRQQKWKSSVSMRAKMPPCDFVPEEYRSYPYERMLKIREQNIAPSLRMYYKKPLLLHQGHMQWLFDYEGRRYLDLFAGIVTVSVGHCHPKVTLAAQKQLACLWHTTNIYMHPSIHEYAEKLTSLLPDPLKVVYLTNSGSEANDLAMFMARLYTRNFDVICLRGAYHGGSPYALGLTSIGSYKHGVANGIGCSTTMLPDVFRGPWGGSNCRDSPVQTVRKCSCSEGVCHANEQYIEQFKDTLNTSVPKTIAGFIAEPIQGINGAVQYPKGFLKEAYRLVRERGGVCIADEVQTGFGRTGSHFWGFQTHDVVPDIITLAKGIGNGFPMAAVVTTKEIANSLAQNLHFNTFGGNPMACVVGSAVLDAIEEDSLQKNSKDVGTYMLLELAKLRDKFEIVGDVRGKGLMIGIEMVTDKDSRHPLPAEEINQIWEDCKDMGVLIGRGGLYNQTFRIKPPMCITRKDVDFAVEVIHTALERHVERAAAN", "length": 497, "header": "tr|A0A8V0YJP6-1|A0A8V0YJP6_CHICK Isoform 1 of Alanine--glyoxylate aminotransferase 2, mitochondrial OS=Gallus gallus OX=9031 GN=AGXT2 PE=1 SV=1 CANONICAL=A0A8V0YJP6-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2U2I2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP6/entry#A0A3Q2U2I2-1", "sequence": { "sequence": "MDAALCLYNSTCLRYEIANSLAQNLHFNTFGGNPMACVVGSAVLDAIEEDSLQKNSKDVGTYMLLELAKLRDKFEIVGDVRGKGLMIGIEMVTDKDSRHPLPAEEINQIWEDCKDMGVLIGRGGLYNQTFRIKPPMCITRKDVDFAVEVIHTALERHVERAAAN", "length": 164, "header": "tr|A0A3Q2U2I2-1|A0A8V0YJP6_CHICK Computationally mapped isoform of Alanine--glyoxylate aminotransferase 2, mitochondrial OS=Gallus gallus OX=9031 GN=AGXT2 PE=1 SV=1 CANONICAL=A0A8V0YJP6-1" }, "locus": { "chromosome": "Z", "start_pos": 11145143, "end_pos": 11140234, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031979.1", "url": "https://www.ensembl.org/id/ENSGALT00010031979.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018769.1", "url": "https://www.ensembl.org/id/ENSGALP00010018769.1" } ] } }, { "isoform_ac": "A0A8V0YJP6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP6/entry#A0A8V0YJP6-1", "sequence": { "sequence": "MAGGLGRGGQLGGVVFRQQKWKSSVSMRAKMPPCDFVPEEYRSYPYERMLKIREQNIAPSLRMYYKKPLLLHQGHMQWLFDYEGRRYLDLFAGIVTVSVGHCHPKVTLAAQKQLACLWHTTNIYMHPSIHEYAEKLTSLLPDPLKVVYLTNSGSEANDLAMFMARLYTRNFDVICLRGAYHGGSPYALGLTSIGSYKHGVANGIGCSTTMLPDVFRGPWGGSNCRDSPVQTVRKCSCSEGVCHANEQYIEQFKDTLNTSVPKTIAGFIAEPIQGINGAVQYPKGFLKEAYRLVRERGGVCIADEVQTGFGRTGSHFWGFQTHDVVPDIITLAKGIGNGFPMAAVVTTKEIANSLAQNLHFNTFGGNPMACVVGSAVLDAIEEDSLQKNSKDVGTYMLLELAKLRDKFEIVGDVRGKGLMIGIEMVTDKDSRHPLPAEEINQIWEDCKDMGVLIGRGGLYNQTFRIKPPMCITRKDVDFAVEVIHTALERHVERAAAN", "length": 497, "header": "tr|A0A8V0YJP6-1|A0A8V0YJP6_CHICK Isoform 1 of Alanine--glyoxylate aminotransferase 2, mitochondrial OS=Gallus gallus OX=9031 GN=AGXT2 PE=1 SV=1 CANONICAL=A0A8V0YJP6-1" }, "locus": { "chromosome": "Z", "start_pos": 11152735, "end_pos": 11140234, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031991.1", "url": "https://www.ensembl.org/id/ENSGALT00010031991.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018781.1", "url": "https://www.ensembl.org/id/ENSGALP00010018781.1" } ] } }, { "isoform_ac": "A0A8V0YLK8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP6/entry#A0A8V0YLK8-1", "sequence": { "sequence": "MAGGLGRGGQLGGVVFRQQKWKSSVSMRAKMPPCDFVPEEYRSYPYERMLKIREQNIAPSLRMYYKKPLLLHQGHMQWLFDYEGRRYLDLFAGIVTVSVGHCHPKVTLAAQKQLACLWHTTNIYMHPSIHEYAEKLTSLLPDPLKVVYLTNSGSEANDLAMFMARLYTRNFDVICLRGAYHGGSPYALGLTSIGSYKHGVANGIGCSTTMLPDVFRGPWGGSNCRDSPVQTVRKCSCSEGVCHANEQYIEQFKDTLNTSVPKTIAGFIAEPIQGINGAVQYPKGFLKEAYRLVRERGGVCIADEVQTGFGRTGSHFWGFQTHDVVPDIITLAKGIGNGFPMAAVVTTKEIANSLAQNLHFNTFGGNPMACVVGSAVLDAIEEDSLQKNSKDVGTYMLLELAKLRDKFEIVGDVRGKGLMIGIEMVTDKDSRHPLPAEEINQIWEDCKDMGVLIGRGGLYNQSCSCVSFAAISYPHFQQRQYKLLLD", "length": 486, "header": "tr|A0A8V0YLK8-1|A0A8V0YLK8_CHICK Computationally mapped isoform of Alanine--glyoxylate aminotransferase 2, mitochondrial OS=Gallus gallus OX=9031 GN=AGXT2 PE=1 SV=1 CANONICAL=A0A8V0YJP6-1" }, "locus": { "chromosome": "Z", "start_pos": 11152735, "end_pos": 11139788, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031982.1", "url": "https://www.ensembl.org/id/ENSGALT00010031982.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018772.1", "url": "https://www.ensembl.org/id/ENSGALP00010018772.1" } ] } }, { "isoform_ac": "A0A8V0YLL2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP6/entry#A0A8V0YLL2-1", "sequence": { "sequence": "MPASHLALQPCRRVVFRQQKWKSSVSMRAKMPPCDFVPEEYRSYPYERMLKIREQNIAPSLRMYYKKPLLLHQGHMQWLFDYEGRRYLDLFAGIVTVSVGHCHPKVTLAAQKQLACLWHTTNIYMHPSIHEYAEKLTSLLPDPLKVVYLTNSGSEANDLAMFMARLYTRNFDVICLRGAYHGGSPYALGLTSIGSYKHGVANGIGCSTTMLPDVFRGPWGGSNCRDSPVQTVRKCSCSEGVCHANEQYIEQFKDTLNTSVPKTIAGFIAEPIQGINGAVQYPKGFLKEAYRLVRERGGVCIADEVQTGFGRTGSHFWGFQTHDVVPDIITLAKGIGNGFPMAAVVTTKEIANSLAQNLHFNTFGGNPMACVVGSAVLDAIEEDSLQKNSKDVGTYMLLELAKLRDKFEIVGDVRGKGLMIGIEMVTDKDSRHPLPAEEINQIWEDCKDMGVLIGRGGLYNQTFRIKPPMCITRKDVDFAVEVIHTALERHVERAAAN", "length": 497, "header": "tr|A0A8V0YLL2-1|A0A8V0YLL2_CHICK Computationally mapped isoform of Alanine--glyoxylate aminotransferase 2, mitochondrial OS=Gallus gallus OX=9031 GN=AGXT2 PE=1 SV=1 CANONICAL=A0A8V0YJP6-1" }, "locus": { "chromosome": "Z", "start_pos": 11152287, "end_pos": 11140234, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031987.1", "url": "https://www.ensembl.org/id/ENSGALT00010031987.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018777.1", "url": "https://www.ensembl.org/id/ENSGALP00010018777.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:431666", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:431666", "resource": "KEGG Pathway" }, { "id": "R-GGA-389661", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-389661", "resource": "Reactome", "description": "Glyoxylate metabolism and glycine degradation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJP6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "pyridoxal phosphate binding", "id": "GO:0030170", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030170", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJP6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP6" } ], "pmid": "" }, { "name": "alanine-glyoxylate transaminase activity", "id": "GO:0008453", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008453", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJP6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP6" } ], "pmid": "" }, { "name": "(R)-3-amino-2-methylpropionate-pyruvate transaminase activity", "id": "GO:0047305", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047305", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJP6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP6" } ], "pmid": "" }, { "name": "beta-alanine:pyruvate transaminase activity", "id": "GO:0016223", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016223", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJP6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "positive regulation of nitric oxide biosynthetic process", "id": "GO:0045429", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045429", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJP6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP6" } ], "pmid": "" }, { "name": "glyoxylate catabolic process", "id": "GO:0009436", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009436", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJP6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP6" } ], "pmid": "" }, { "name": "glycine biosynthetic process, by transamination of glyoxylate", "id": "GO:0019265", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019265", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJP6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP6" } ], "pmid": "" }, { "name": "L-alanine catabolic process, by transamination", "id": "GO:0019481", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019481", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJP6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 257, "end_pos": 259, "annotation": "n_glycosylation_sequon" }, { "start_pos": 460, "end_pos": 462, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "14077", "name": "", "equation": "3-oxopropanoate + L-alanine = beta-alanine + pyruvate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YJP6-1" ], "evidence": [ { "id": "14077", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/14077" } ] }, { "id": "18393", "name": "", "equation": "(R)-3-amino-2-methylpropanoate + pyruvate = 2-methyl-3-oxopropanoate + L-alanine", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YJP6-1" ], "evidence": [ { "id": "18393", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/18393" } ] }, { "id": "24248", "name": "", "equation": "glyoxylate + L-alanine = glycine + pyruvate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V1A124-1", "A0A8V0YJP6-1" ], "evidence": [ { "id": "24248", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/24248" } ] }, { "id": "77303", "name": "", "equation": "N(omega),N(omega)-dimethyl-L-arginine + pyruvate = 5-(3,3-dimethylguanidino)-2-oxopentanoate + L-alanine", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YJP6-1" ], "evidence": [ { "id": "77303", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/77303" } ] }, { "id": "77307", "name": "", "equation": "N(omega),N('omega)-dimethyl-L-arginine + pyruvate = 5-(3,3'-dimethylguanidino)-2-oxopentanoate + L-alanine", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YJP6-1" ], "evidence": [ { "id": "77307", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/77307" } ] }, { "id": "77311", "name": "", "equation": "N(omega),N(omega)-dimethyl-L-arginine + glyoxylate = 5-(3,3-dimethylguanidino)-2-oxopentanoate + glycine", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YJP6-1" ], "evidence": [ { "id": "77311", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/77311" } ] }, { "id": "77315", "name": "", "equation": "N(omega),N('omega)-dimethyl-L-arginine + glyoxylate = 5-(3,3'-dimethylguanidino)-2-oxopentanoate + glycine", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YJP6-1" ], "evidence": [ { "id": "77315", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/77315" } ] }, { "id": "77319", "name": "", "equation": "N(omega)-methyl-L-arginine + pyruvate = 5-(3-methylguanidino)-2-oxopentanoate + L-alanine", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YJP6-1" ], "evidence": [ { "id": "77319", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/77319" } ] }, { "id": "77323", "name": "", "equation": "N(omega)-methyl-L-arginine + glyoxylate = 5-(3-methylguanidino)-2-oxopentanoate + glycine", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YJP6-1" ], "evidence": [ { "id": "77323", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/77323" } ] }, { "id": "77327", "name": "", "equation": "L-ornithine + pyruvate = 5-amino-2-oxopentanoate + L-alanine", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YJP6-1" ], "evidence": [ { "id": "77327", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/77327" } ] }, { "id": "77331", "name": "", "equation": "L-ornithine + glyoxylate = 5-amino-2-oxopentanoate + glycine", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YJP6-1" ], "evidence": [ { "id": "77331", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/77331" } ] }, { "id": "77339", "name": "", "equation": "(2S)-2-aminobutanoate + glyoxylate = 2-oxobutanoate + glycine", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YJP6-1" ], "evidence": [ { "id": "77339", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/77339" } ] }, { "id": "77343", "name": "", "equation": "N(omega),N(omega)-dimethyl-L-arginine + oxaloacetate = 5-(3,3-dimethylguanidino)-2-oxopentanoate + L-aspartate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YJP6-1" ], "evidence": [ { "id": "77343", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/77343" } ] }, { "id": "77347", "name": "", "equation": "oxaloacetate + L-alanine = L-aspartate + pyruvate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YJP6-1" ], "evidence": [ { "id": "77347", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/77347" } ] }, { "id": "77351", "name": "", "equation": "N(omega),N(omega)-dimethyl-L-arginine + 2-oxobutanoate = 5-(3,3-dimethylguanidino)-2-oxopentanoate + (2S)-2-aminobutanoate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YJP6-1" ], "evidence": [ { "id": "77351", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/77351" } ] }, { "id": "77355", "name": "", "equation": "2-oxobutanoate + L-alanine = (2S)-2-aminobutanoate + pyruvate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YJP6-1" ], "evidence": [ { "id": "77355", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/77355" } ] }, { "id": "77359", "name": "", "equation": "2-oxopentanoate + N(omega),N(omega)-dimethyl-L-arginine = 5-(3,3-dimethylguanidino)-2-oxopentanoate + L-2-aminopentanoate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YJP6-1" ], "evidence": [ { "id": "77359", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/77359" } ] }, { "id": "77363", "name": "", "equation": "2-oxohexanoate + N(omega),N(omega)-dimethyl-L-arginine = L-2-aminohexanoate + 5-(3,3-dimethylguanidino)-2-oxopentanoate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YJP6-1" ], "evidence": [ { "id": "77363", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/77363" } ] }, { "id": "R-GGA-904864", "name": "Mitochondrial AGXT2 tetramer transaminates glyoxylate and alanine to glycine and pyruvate", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial matrix", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YJP6-1" ], "evidence": [ { "id": "R-GGA-904864", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-904864" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0YJP6", "gene_name": "AGXT2", "activity": [ { "ec_number": "2.6.1.40", "activity": "(R)-3-amino-2-methylpropanoate + pyruvate = 2-methyl-3-oxopropanoate + L-alanine.", "evidence": [ { "id": "A0A8V0YJP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP6" } ] }, { "ec_number": "2.6.1.44", "activity": "2-oxobutanoate + L-alanine = (2S)-2-aminobutanoate + pyruvate.", "evidence": [ { "id": "A0A8V0YJP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP6" } ] }, { "ec_number": "2.6.1.18", "activity": "3-oxopropanoate + L-alanine = beta-alanine + pyruvate.", "evidence": [ { "id": "A0A8V0YJP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP6" } ] }, { "ec_number": "2.6.1.44", "activity": "", "evidence": [ { "id": "A0A8V0YJP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP6" } ] }, { "ec_number": "2.6.1.18", "activity": "", "evidence": [ { "id": "A0A8V0YJP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP6" } ] }, { "ec_number": "2.6.1.40", "activity": "", "evidence": [ { "id": "A0A8V0YJP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP6" } ] } ] }, { "uniprot_ac": "A0A8V1A124", "gene_name": "AGXT", "activity": [ { "ec_number": "2.6.1.51", "activity": "L-serine + pyruvate = 3-hydroxypyruvate + L-alanine.", "evidence": [ { "id": "A0A8V1A124", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A124" } ] }, { "ec_number": "2.6.1.44", "activity": "2-oxobutanoate + L-alanine = (2S)-2-aminobutanoate + pyruvate.", "evidence": [ { "id": "A0A8V1A124", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A124" } ] }, { "ec_number": "2.6.1.44", "activity": "", "evidence": [ { "id": "A0A8V1A124", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A124" } ] }, { "ec_number": "2.6.1.51", "activity": "", "evidence": [ { "id": "A0A8V1A124", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A124" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.6.1.40", "ec_name": "(R)-3-amino-2-methylpropanoate + pyruvate = 2-methyl-3-oxopropanoate + L-alanine.", "evidence": [ { "id": "2.6.1.40", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.6.1.40" }, { "id": "2.6.1.40", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.6.1.40" } ] }, { "ec_number": "2.6.1.44", "ec_name": "2-oxobutanoate + L-alanine = (2S)-2-aminobutanoate + pyruvate.", "evidence": [ { "id": "2.6.1.44", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.6.1.44" }, { "id": "2.6.1.44", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.6.1.44" } ] }, { "ec_number": "2.6.1.18", "ec_name": "3-oxopropanoate + L-alanine = beta-alanine + pyruvate.", "evidence": [ { "id": "2.6.1.18", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.6.1.18" }, { "id": "2.6.1.18", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.6.1.18" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 257, "end_pos": 259 }, { "start_pos": 460, "end_pos": 462 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], 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"MGCVQCKDKEATKLTDERDGSLTQSSGYRYGTDPTPQHYPSFGVTSIPNYNNFHATGGQGLTVFGGVNSSSHTGTLRTRGGTGVTLFVALYDYEARTEDDLSFHKGEKFQILNSSEGDWWEARSLTTGETGYIPSNYVAPVDSIQAEEWYFGKLGRKDAERQLLSFGNPRGTFLIRESETTKGAYSLSIRDWDDMKGDHVKHYKIRKLDNGGYYITTRAQFETLQQLVQHYSERAAGLCCRLVVPCHKGMPRLTDLSVKTKDVWEIPRESLQLIKRLGNGQFGEVWMEKADGLCFNLTVIATNNTPQTVGLAKDAWEVARDSLFLEQKLGQGCFAEVWRGTWNGNTKVAIKTLKPGTMSPESFLEEAQIMKKLKHDKLVQLYAVVSEEPIYIVTEYMSKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCPQDCPISLHELMIHCWKKDPEERPTFEYLQGFLEDYFTATEPQYQPGDNL", "length": 589, "header": "tr|A0A3Q2U639-1|A0A3Q2U639_CHICK Isoform 1 of Tyrosine-protein kinase OS=Gallus gallus OX=9031 GN=FYN PE=3 SV=1 CANONICAL=A0A3Q2U639-1" }, "locus": { "chromosome": "3", "start_pos": 65708395, "end_pos": 65671404, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032718.1", "url": "https://www.ensembl.org/id/ENSGALT00010032718.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019384.1", "url": "https://www.ensembl.org/id/ENSGALP00010019384.1" } ] } }, { "isoform_ac": "A0A3Q2UIT4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U639/entry#A0A3Q2UIT4-1", "sequence": { "sequence": "MGCVQCKDKEATKLTDERDGSLTQSSGYRYGTDPTPQHYPSFGVTSIPNYNNFHATGGQGLTVFGGVNSSSHTGTLRTRGGTGVTLFVALYDYEARTEDDLSFHKGEKFQILNSSEGDWWEARSLTTGETGYIPSNYVAPVDSIQAEEWYFGKLGRKDAERQLLSFGNPRGTFLIRESETTKGAYSLSIRDWDDMKGDHVKHYKIRKLDNGGYYITTRAQFETLQQLVQHYSERAAGLCCRLVVPCHKGMPRLTDLSVKTKDVWEIPRESLQLIKRLGNGQFGEVWMGTWNGNTKVAIKTLKPGTMSPESFLEEAQIMKKLKHDKLVQLYAVVSEEPIYIVTEYMSKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCPQDCPISLHELMIHCWKKDPEERPTFEYLQGFLEDYFTATEPQYQPGDNL", "length": 537, "header": "tr|A0A3Q2UIT4-1|A0A3Q2U639_CHICK Computationally mapped isoform of Tyrosine-protein kinase OS=Gallus gallus OX=9031 GN=FYN PE=3 SV=1 CANONICAL=A0A3Q2U639-1" }, "locus": { "chromosome": "3", "start_pos": 65708395, "end_pos": 65671404, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032694.1", "url": "https://www.ensembl.org/id/ENSGALT00010032694.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019373.1", "url": "https://www.ensembl.org/id/ENSGALP00010019373.1" } ] } }, { "isoform_ac": "A0A8V0YEZ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U639/entry#A0A8V0YEZ9-1", "sequence": { "sequence": "MGCVQCKDKEATKLTDERDGSLTQSSGYRYGTDPTPQHYPSFGVTSIPNYNNFHATGGQGLTVFGGVNSSSHTGTLRTRGGTGVTLFVALYDYEARTEDDLSFHKGEKFQILNSSEGDWWEARSLTTGETGYIPSNYVAPVDSIQAEEWYFGKLGRKDAERQLLSFGNPRGTFLIRESETTKGAYSLSIRDWDDMKGDHVKHYKIRKLDNGGYYITTRAQFETLQQLVQHYSERAAGLCCRLVVPCHKGMPRLTDLSVKTKDVWEIPRESLQLIKRLGNGQFGEVWMGTWNGNTKVAIKTLKPGTMSPESFLEEAQIMKKLKHDKLVQLYAVVSEEPIYIVTEYMSKDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCPQDCPISLHELMIHCWKKDPEERPTFEYLQGFLEDYFTATEPQYQPGDNL", "length": 533, "header": "tr|A0A8V0YEZ9-1|A0A8V0YEZ9_CHICK Computationally mapped isoform of Tyrosine-protein kinase OS=Gallus gallus OX=9031 GN=FYN PE=3 SV=1 CANONICAL=A0A3Q2U639-1" }, "locus": { "chromosome": "3", "start_pos": 65708395, "end_pos": 65671404, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032757.1", "url": "https://www.ensembl.org/id/ENSGALT00010032757.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019406.1", "url": "https://www.ensembl.org/id/ENSGALP00010019406.1" } ] } }, { "isoform_ac": "A0A8V0YF04-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U639/entry#A0A8V0YF04-1", "sequence": { "sequence": "MGCVQCKDKEATKLTDERDGSLTQSSGYRYGTDPTPQHYPSFGVTSIPNYNNFHATGGQGLTVFGGVNSSSHTGTLRTRGGTGVTLFVALYDYEARTEDDLSFHKGEKFQILNSSEGDWWEARSLTTGETGYIPSNYVAPVDSIQAEEWYFGKLGRKDAERQLLSFGNPRGTFLIRESETTKGAYSLSIRDWDDMKGDHVKHYKIRKLDNGGYYITTRAQFETLQQLVQHYSGTWNGNTKVAIKTLKPGTMSPESFLEEAQIMKKLKHDKLVQLYAVVSEEPIYIVTEYMSKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCPQDCPISLHELMIHCWKKDPEERPTFEYLQGFLEDYFTATEPQYQPGDNL", "length": 482, "header": "tr|A0A8V0YF04-1|A0A8V0YF04_CHICK Computationally mapped isoform of Tyrosine-protein kinase OS=Gallus gallus OX=9031 GN=FYN PE=3 SV=1 CANONICAL=A0A3Q2U639-1" }, "locus": { "chromosome": "3", "start_pos": 65708395, "end_pos": 65671404, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032765.1", "url": "https://www.ensembl.org/id/ENSGALT00010032765.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019411.1", "url": "https://www.ensembl.org/id/ENSGALP00010019411.1" } ] } }, { "isoform_ac": "A0A8V0YF08-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U639/entry#A0A8V0YF08-1", "sequence": { "sequence": "MGCVQCKDKEATKLTDERDGSLTQSSGYRYGTDPTPQHYPSFGVTSIPNYNNFHATGGQGLTVFGGVNSSSHTGTLRTRGGTGVTLFVALYDYEARTEDDLSFHKGEKFQILNSSEGDWWEARSLTTGETGYIPSNYVAPVDSIQAEEWYFGKLGRKDAERQLLSFGNPRGTFLIRESETTKGAYSLSIRDWDDMKGDHVKHYKIRKLDNGGYYITTRAQFETLQQLVQHYSEKADGLCFNLTVIATNNTPQTVGLAKDAWEVARDSLFLEQKLGQGCFAEVVLLGTWNGNTKVAIKTLKPGTMSPESFLEEAQIMKKLKHDKLVQLYAVVSEEPIYIVTEYMSKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCPQDCPISLHELMIHCWKKDPEERPTFEYLQGFLEDYFTATEPQYQPGDNL", "length": 535, "header": "tr|A0A8V0YF08-1|A0A8V0YF08_CHICK Computationally mapped isoform of Tyrosine-protein kinase OS=Gallus gallus OX=9031 GN=FYN PE=3 SV=1 CANONICAL=A0A3Q2U639-1" }, "locus": { "chromosome": "3", "start_pos": 65708395, "end_pos": 65671404, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032778.1", "url": "https://www.ensembl.org/id/ENSGALT00010032778.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019416.1", "url": "https://www.ensembl.org/id/ENSGALP00010019416.1" } ] } }, { "isoform_ac": "A0A8V0YN66-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U639/entry#A0A8V0YN66-1", "sequence": { "sequence": "MGCVQCKDKEATKLTDERDGSLTQSSGYRYGTDPTPQHYPSFGVTSIPNYNNFHATGGQGVTLFVALYDYEARTEDDLSFHKGEKFQILNSSEGDWWEARSLTTGETGYIPSNYVAPVDSIQAEEWYFGKLGRKDAERQLLSFGNPRGTFLIRESETTKGAYSLSIRDWDDMKGDHVKHYKIRKLDNGGYYITTRAQFETLQQLVQHYSEKADGLCFNLTVIATNNTPQTVGLAKDAWEVARDSLFLEQKLGQGCFAEVWRGTWNGNTKVAIKTLKPGTMSPESFLEEAQIMKKLKHDKLVQLYAVVSEEPIYIVTEYMSKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCPQDCPISLHELMIHCWKKDPEERPTFEYLQGFLEDYFTATEPQYQPGDNL", "length": 511, "header": "tr|A0A8V0YN66-1|A0A8V0YN66_CHICK Computationally mapped isoform of Tyrosine-protein kinase OS=Gallus gallus OX=9031 GN=FYN PE=3 SV=1 CANONICAL=A0A3Q2U639-1" }, "locus": { "chromosome": "3", "start_pos": 65708395, "end_pos": 65671404, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032741.1", "url": "https://www.ensembl.org/id/ENSGALT00010032741.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019399.1", "url": "https://www.ensembl.org/id/ENSGALP00010019399.1" } ] } }, { "isoform_ac": "F1NQU9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U639/entry#F1NQU9-1", "sequence": { "sequence": "MGCVQCKDKEATKLTDERDGSLTQSSGYRYGTDPTPQHYPSFGVTSIPNYNNFHATGGQGLTVFGGVNSSSHTGTLRTRGGTGVTLFVALYDYEARTEDDLSFHKGEKFQILNSSEGDWWEARSLTTGETGYIPSNYVAPVDSIQAEEWYFGKLGRKDAERQLLSFGNPRGTFLIRESETTKGAYSLSIRDWDDMKGDHVKHYKIRKLDNGGYYITTRAQFETLQQLVQHYSEKADGLCFNLTVIATNNTPQTVGLAKDAWEVARDSLFLEQKLGQGCFAEVWRGTWNGNTKVAIKTLKPGTMSPESFLEEAQIMKKLKHDKLVQLYAVVSEEPIYIVTEYMSKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCPQDCPISLHELMIHCWKKDPEERPTFEYLQGFLEDYFTATEPQYQPGDNL", "length": 534, "header": "tr|F1NQU9-1|A0A3Q2U639_CHICK Computationally mapped isoform of Tyrosine-protein kinase OS=Gallus gallus OX=9031 GN=FYN PE=3 SV=3 CANONICAL=A0A3Q2U639-1" }, "locus": { "chromosome": "3", "start_pos": 65708395, "end_pos": 65671404, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032702.1", "url": "https://www.ensembl.org/id/ENSGALT00010032702.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019376.1", "url": "https://www.ensembl.org/id/ENSGALP00010019376.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:396294", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:396294", "resource": "KEGG Pathway" }, { "id": "R-GGA-1227986", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1227986", "resource": "Reactome", "description": "Signaling by ERBB2" }, { "id": "R-GGA-1257604", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1257604", "resource": "Reactome", "description": "PIP3 activates AKT signaling" }, { "id": "R-GGA-1433557", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1433557", "resource": "Reactome", "description": "Signaling by SCF-KIT" }, { "id": "R-GGA-1433559", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1433559", "resource": "Reactome", "description": "Regulation of KIT signaling" }, { "id": "R-GGA-210990", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-210990", "resource": "Reactome", "description": "PECAM1 interactions" }, { "id": "R-GGA-373753", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-373753", "resource": "Reactome", "description": "Nephrin family interactions" }, { "id": "R-GGA-375165", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-375165", "resource": "Reactome", "description": "NCAM signaling for neurite out-growth" }, { "id": "R-GGA-389356", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-389356", "resource": "Reactome", "description": "Co-stimulation by CD28" }, { "id": "R-GGA-389357", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-389357", "resource": "Reactome", "description": "CD28 dependent PI3K/Akt signaling" }, { "id": "R-GGA-389359", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-389359", "resource": "Reactome", "description": "CD28 dependent Vav1 pathway" }, { "id": "R-GGA-389513", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-389513", "resource": "Reactome", "description": "Co-inhibition by CTLA4" }, { "id": "R-GGA-3928662", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3928662", "resource": "Reactome", "description": "EPHB-mediated forward signaling" }, { "id": "R-GGA-3928663", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3928663", "resource": "Reactome", "description": "EPHA-mediated growth cone collapse" }, { "id": "R-GGA-3928664", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3928664", "resource": "Reactome", "description": "Ephrin signaling" }, { "id": "R-GGA-3928665", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3928665", "resource": "Reactome", "description": "EPH-ephrin mediated repulsion of cells" }, { "id": "R-GGA-399954", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-399954", "resource": "Reactome", "description": "Sema3A PAK dependent Axon repulsion" }, { "id": "R-GGA-399955", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-399955", "resource": "Reactome", "description": "SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion" }, { "id": "R-GGA-399956", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-399956", "resource": "Reactome", "description": "CRMPs in Sema3A signaling" }, { "id": "R-GGA-4420097", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4420097", "resource": "Reactome", "description": "VEGFA-VEGFR2 Pathway" }, { "id": "R-GGA-5621575", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5621575", "resource": "Reactome", "description": "CD209 (DC-SIGN) signaling" }, { "id": "R-GGA-5673001", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5673001", "resource": "Reactome", "description": "RAF/MAP kinase cascade" }, { "id": "R-GGA-6811558", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6811558", "resource": "Reactome", "description": "PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling" }, { "id": "R-GGA-8866376", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8866376", "resource": "Reactome", "description": "Reelin signalling pathway" }, { "id": "R-GGA-9032759", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9032759", "resource": "Reactome", "description": "NTRK2 activates RAC1" }, { "id": "R-GGA-912631", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-912631", "resource": "Reactome", "description": "Regulation of signaling by CBL" }, { "id": "R-GGA-9766229", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9766229", "resource": "Reactome", "description": "Degradation of CDH1" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2QHC0-1", "protein_name": "Tyrosine-protein kinase", "gene_name": "Fyn", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MGCVQCKDKEAAKLTEERDGSLNQSSGYRYGTDPTPQHYPSFGVTSIPNYNNFHAAGGQGLTVFGGVNSSSHTGTLRTRGGTGVTLFVALYDYEARTEDDLSFHKGEKFQILNSSEGDWWEARSLTTGETGYIPSNYVAPVDSIQAEEWYFGKLGRKDAERQLLSFGNPRGTFLIRESETTKGAYSLSIRDWDDMKGDHVKHYKIRKLDNGGYYITTRAQFETLQQLVQHYSERAAGLCCRLVVPCHKGMPRLTDLSVKTKDVWEIPRESLQLIKRLGNGQFGEVWMGTWNGNTKVAIKTLKPGTMSPESFLEEAQIMKKLKHDKLVQLYAVVSEEPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCPQDCPISLHELMIHCWKKDPEERPTFEYLQGFLEDYFTATEPQYQPGENL", "length": 537 }, "evidence": [ { "id": "A0A3Q2U639", "url": "https://omabrowser.org/oma/group/A0A3Q2U639/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0JNB0-1", "protein_name": "Tyrosine-protein kinase Fyn", "gene_name": "FYN", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGCVQCKDKEATKLTEERDGSLNQSSGYRYGTDPTPQHYPSFGVTSIPNYNNFHGAGGQGLTVFGGVNSSSHTGTLRTRGGTGVTLFVALYDYEARTEDDLSFHKGEKFQILNSSEGDWWEARSLTTGETGYIPSNYVAPVDSIQAEEWYFGKLGRKDAERQLLSFGNPRGTFLIRESETTKGAYSLSIRDWDDMKGDHVKHYKIRKLDNGGYYITTRAQFETLQQLVQHYSERAAGLCCRLVVPCHKGMPRLTDLSVKTKDVWEIPRESLQLIKRLGNGQFGEVWMGTWNGNTKVAIKTLKPGTMSPESFLEEAQIMKKLKHDKLVQLYAVVSEEPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCPQDCPISLHELMIHCWKKDPEERPTFEYLQGFLEDYFTATEPQYQPGENL", "length": 537 }, "evidence": [ { "id": "A0A3Q2U639", "url": "https://omabrowser.org/oma/group/A0A3Q2U639/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A1Y2K1-1", "protein_name": "Tyrosine-protein kinase Fyn", "gene_name": "FYN", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGCVQCKDKEATKLTEERDGSLNQSSGFRYGTDPTPQHYPSFGVTSIPNYNNFHAAGGQGLTVFGGVSSSSHTGTLRTRGGTGVTLFVALYDYEARTEDDLSFHKGEKFQILNSSEGDWWEARSLTTGETGYIPSNYVAPVDSIQAEEWYFGKLGRKDAERQLLSFGNPRGTFLIRESETTKGAYSLSIRDWDDMKGDHVKHYKIRKLDNGGYYITTRAQFETLQQLVQHYSERAAGLCCRLVVPCHKGMPRLTDLSVKTKDVWEIPRESLQLIKRLGNGQFGEVWMGTWNGNTKVAIKTLKPGTMSPESFLEEAQIMKKLKHDKLVQLYAVVSEEPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCPQDCPISLHELMIHCWKKDPEERPTFEYLQGFLEDYFTATEPQYQPGENL", "length": 537 }, "evidence": [ { "id": "A0A3Q2U639", "url": "https://omabrowser.org/oma/group/A0A3Q2U639/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P06241-1", "protein_name": "Tyrosine-protein kinase Fyn", "gene_name": "FYN", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGCVQCKDKEATKLTEERDGSLNQSSGYRYGTDPTPQHYPSFGVTSIPNYNNFHAAGGQGLTVFGGVNSSSHTGTLRTRGGTGVTLFVALYDYEARTEDDLSFHKGEKFQILNSSEGDWWEARSLTTGETGYIPSNYVAPVDSIQAEEWYFGKLGRKDAERQLLSFGNPRGTFLIRESETTKGAYSLSIRDWDDMKGDHVKHYKIRKLDNGGYYITTRAQFETLQQLVQHYSERAAGLCCRLVVPCHKGMPRLTDLSVKTKDVWEIPRESLQLIKRLGNGQFGEVWMGTWNGNTKVAIKTLKPGTMSPESFLEEAQIMKKLKHDKLVQLYAVVSEEPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCPQDCPISLHELMIHCWKKDPEERPTFEYLQSFLEDYFTATEPQYQPGENL", "length": 537 }, "evidence": [ { "id": "A0A3Q2U639", "url": "https://omabrowser.org/oma/group/A0A3Q2U639/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P39688-1", "protein_name": "Tyrosine-protein kinase Fyn", "gene_name": "Fyn", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGCVQCKDKEAAKLTEERDGSLNQSSGYRYGTDPTPQHYPSFGVTSIPNYNNFHAAGGQGLTVFGGVNSSSHTGTLRTRGGTGVTLFVALYDYEARTEDDLSFHKGEKFQILNSSEGDWWEARSLTTGETGYIPSNYVAPVDSIQAEEWYFGKLGRKDAERQLLSFGNPRGTFLIRESETTKGAYSLSIRDWDDMKGDHVKHYKIRKLDNGGYYITTRAQFETLQQLVQHYSERAAGLCCRLVVPCHKGMPRLTDLSVKTKDVWEIPRESLQLIKRLGNGQFGEVWMGTWNGNTKVAIKTLKPGTMSPESFLEEAQIMKKLKHDKLVQLYAVVSEEPIYIVTEYMSKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCPQDCPISLHELMIHCWKKDPEERPTFEYLQGFLEDYFTATEPQYQPGENL", "length": 537 }, "evidence": [ { "id": "A0A3Q2U639", "url": "https://omabrowser.org/oma/group/A0A3Q2U639/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q62844-1", "protein_name": "Tyrosine-protein kinase Fyn", "gene_name": "Fyn", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGCVQCKDKEAAKLTEERDGSLNQSSGYRYGTDPTPQHYPSFGVTSIPNYNNFHAAGGQGLTVFGGVNSSSHTGTLRTRGGTGVTLFVALYDYEARTEDDLSFHKGEKFQILNSSEGDWWEARSLTTGETGYIPSNYVAPVDSIQAEEWYFGKLGRKDAERQLLSFGNPRGTFLIRESETTKGAYSLSIRDWDDMKGDHVKHYKIRKLDNGGYYITTRAQFETLQQLVQHYSERAAGLCCRLVVPCHKGMPRLTDLSVKTKDVWEIPRESLQLIKRLGNGQFGEVWMGTWNGNTKVAIKTLKPGTMSPESFLEEAQIMKKLKHDKLVQLYAVVSEEPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCPQDCPISLHELMIHCWKKDPEERPTFEYLQGFLEDYFTATEPQYQPGENL", "length": 537 }, "evidence": [ { "id": "A0A3Q2U639", "url": "https://omabrowser.org/oma/group/A0A3Q2U639/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6EWH2-1", "protein_name": "Tyrosine-protein kinase fyna", "gene_name": "fyna", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGCVQCKDKEATKLTDERETSVSQHAGYRYGSDPTPQHYPSFGVTAIPNYNNFHAPVSQGVTVFGGVNSSSHSGTLRSRGGTGVTLFVALYDYEARSEDDLSFRKGEKFQILNSTEGDWWEARSLTTGGTGYIPSNYVAPVDSIQAEDWYFGKLGRKDAERQLLSNGNPRGTFLIRESETTKGAYSLSIQDWDETKGDHVKHYKIRKLDNGGYYITTRAQFETLQQLVHHYSARAAGLCCRLIVPCHKGMPRLADLSVKTKDVWEIPRESLQLIKRLGNGQFGEVWMGTWNGNTKVAVKTLKPGTMSPESFLEEAQIMKKLRHDKLVQLYAVVSEEPIYIVTEYMSKGSLLDFLKDGEGRGLKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGDSLVCKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCPQDCPSSLHELMLQCWKRDPEERPTFEYLQAFLEDYFTATEPQYQPGDNL", "length": 537 }, "evidence": [ { "id": "A0A3Q2U639", "url": "https://omabrowser.org/oma/group/A0A3Q2U639/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 15, "go_terms": [ { "name": "non-membrane spanning protein tyrosine kinase activity", "id": "GO:0004715", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004715", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U639", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U639" } ], "pmid": "" }, { "name": "signaling receptor binding", "id": "GO:0005102", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005102", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U639", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U639" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U639", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U639" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U639", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U639" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U639", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U639" } ], "pmid": "" }, { "name": "ephrin receptor binding", "id": "GO:0046875", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046875", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U639", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U639" } ], "pmid": "" }, { "name": "growth factor receptor binding", "id": "GO:0070851", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070851", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U639", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U639" } ], "pmid": "" }, { "name": "G protein-coupled receptor binding", "id": "GO:0001664", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001664", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U639", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U639" } ], "pmid": "" }, { "name": "transmembrane transporter binding", "id": "GO:0044325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044325", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U639", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U639" } ], "pmid": "" }, { "name": "tau protein binding", "id": "GO:0048156", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048156", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U639", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U639" } ], "pmid": "" }, { "name": "scaffold protein binding", "id": "GO:0097110", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097110", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U639", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U639" } ], "pmid": "" }, { "name": "phospholipase activator activity", "id": "GO:0016004", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016004", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U639", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U639" } ], "pmid": "" }, { "name": "phospholipase binding", "id": "GO:0043274", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043274", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U639", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U639" } ], "pmid": "" }, { "name": "alpha-tubulin binding", "id": "GO:0043014", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043014", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U639", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U639" } ], "pmid": "" }, { "name": "disordered domain specific binding", "id": "GO:0097718", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097718", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U639", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U639" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 10, "go_terms": [ { "name": "endosome", "id": "GO:0005768", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005768", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U639", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U639" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U639", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U639" } ], "pmid": "" }, { "name": "actin filament", "id": "GO:0005884", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005884", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U639", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U639" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U639", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U639" } ], "pmid": "" }, { "name": "postsynaptic density", "id": "GO:0014069", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014069", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U639", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U639" } ], "pmid": "" }, { "name": "dendrite", "id": "GO:0030425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U639", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U639" } ], "pmid": "" }, { "name": "membrane raft", "id": "GO:0045121", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045121", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U639", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U639" } ], "pmid": "" }, { "name": "cell body", "id": "GO:0044297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044297", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U639", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U639" } ], "pmid": "" }, { "name": "glial cell projection", "id": "GO:0097386", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097386", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U639", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U639" } ], "pmid": "" }, { "name": "Schaffer collateral - CA1 synapse", "id": "GO:0098685", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098685", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U639", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U639" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 18, "go_terms": [ { "name": "cell surface receptor protein tyrosine kinase signaling pathway", "id": "GO:0007169", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007169", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U639", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U639" } ], "pmid": "" }, { "name": "negative regulation of gene expression", "id": "GO:0010629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010629", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U639", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U639" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U639", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U639" } ], "pmid": "" }, { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U639", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U639" } ], "pmid": "" }, { "name": "cellular response to amyloid-beta", "id": "GO:1904646", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904646", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U639", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U639" } ], "pmid": "" }, { "name": "T cell receptor signaling pathway", "id": "GO:0050852", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050852", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U639", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U639" } ], "pmid": "" }, { "name": "negative regulation of angiogenesis", "id": "GO:0016525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016525", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U639", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U639" } ], "pmid": "" }, { "name": "modulation of chemical synaptic transmission", "id": "GO:0050804", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050804", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U639", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U639" } ], "pmid": "" }, { "name": "positive regulation of protein targeting to membrane", "id": "GO:0090314", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090314", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U639", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U639" } ], "pmid": "" }, { "name": "negative regulation of dendritic spine maintenance", "id": "GO:1902951", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902951", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U639", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U639" } ], "pmid": "" }, { "name": "natural killer cell activation", "id": "GO:0030101", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030101", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U639", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U639" } ], "pmid": "" }, { "name": "negative regulation of T cell receptor signaling pathway", "id": "GO:0050860", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050860", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U639", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U639" } ], "pmid": "" }, { "name": "negative regulation of T cell activation", "id": "GO:0050868", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050868", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U639", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U639" } ], "pmid": "" }, { "name": "reelin-mediated signaling pathway", "id": "GO:0038026", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038026", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U639", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U639" } ], "pmid": "" }, { "name": "regulation of calcium ion import across plasma membrane", "id": "GO:1905664", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905664", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U639", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U639" } ], "pmid": "" }, { "name": "G protein-coupled glutamate receptor signaling pathway", "id": "GO:0007216", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007216", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U639", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U639" } ], "pmid": "" }, { "name": "regulation of glutamate receptor signaling pathway", "id": "GO:1900449", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900449", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U639", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U639" } ], "pmid": "" }, { "name": "heart process", "id": "GO:0003015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003015", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U639", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U639" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 113, "end_pos": 115, "annotation": "n_glycosylation_sequon" }, { "start_pos": 296, "end_pos": 298, "annotation": "n_glycosylation_sequon" }, { "start_pos": 303, "end_pos": 305, "annotation": "n_glycosylation_sequon" }, { "start_pos": 68, "end_pos": 70, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "10596", "name": "", "equation": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V1ADF0-1", "F1N9Y5-1", "A0A8V0XQG0-1", "A0A8V0Y9A0-1", "A0A8V1AFM7-1", "A0A8V0Z0R8-1", "A0A8V0Z4B2-1", "A0A8V0ZBN6-1", "P09324-1", "A0A8V0XHW1-1", "A0A8V0YW12-1", "A0A8V0YUJ4-1", "A0A8V0ZSN8-1", "F1NVF2-1", "A0A8V1AKW4-1", "A0A8V0XB17-1", "A0A8V0ZC34-1", "A0A8V0YYC1-1", "A0A8V0ZND5-1", "A0A8V1ACF7-1", "A0A8V0ZP30-1", "E1BTE1-1", "Q07497-1", "A0A8V0X6E7-1", "F1NCL8-1", "A0A8V0XNF4-1", "A0A8V0XN86-1", "A0A8V0YEV0-1", "A0A8V0XQ80-1", "A0A8V0XZ82-1", "A0A8V0YZE5-1", "A0A8V0YYZ7-1", "A0A8V0YCV8-1", "A0A8V0YGR1-1", "A0A8V0YNY4-1", "A0A8V0YXM5-1", "A0A8V0YXZ9-1", "A0A3Q2UKD3-1", "A0A8V0YIT6-1", "A0A8V0YIV6-1", "R4GJW5-1", "A0A8V1A3N1-1", "A0A8V1A9R2-1", "A0A8V0ZE65-1", "A0A8V0ZER1-1", "A0A8V0ZXS7-1", "A0A8V1A7N1-1", "H9KZZ1-1", "F1NQL9-1", "A0A8V1ABP4-1", "F1NZY8-1", "Q02977-1", "A0A1D5PD64-1", "A0A8V0ZDU6-1", "A0A3Q2U1T2-1", "R4GJB8-1", "A0A3Q2U639-1", "A0A8V0X5W9-1", "E1C7Z1-1", "A0A8V0Y7Y3-1", "Q5ZIU3-1", "A0A8V0YPR4-1", "A0A8V0YT43-1", "A0A8V0Z3S3-1", "A0A8V0YJJ1-1", "A0A8V0YKP8-1", "A0A8V0YZ74-1", "A0A8V0ZWV8-1", "A0A8V1A069-1", "A0A8V1A7E0-1", "A0A8V1AEL3-1", "E1BTT3-1", "F1N996-1", "H9KZZ2-1", "E1C2C8-1", "Q05876-1", "Q90891-1", "O42422-1", "P00523-1", "P08941-1", "P13387-1", "P18460-1", "P18461-1", "P21804-1", "P28693-1", "P29318-1", "P42683-1", "P54755-1", "Q00944-1", "Q07494-1", "Q07496-1", "Q07498-1", "Q08156-1", "Q6XUX0-1", "Q75R65-1", "Q8AXY6-1", "Q8JH64-1", "Q8QHL3-1", "Q91009-1", "Q91044-1", "Q91987-1", "Q98949-1", "Q9PUF6-1", "F1NW21-1", "A0A8V0YLC3-1", "A0A8V0Z7L6-1", "F1NJX6-1", "A0A8V0YUC4-1", "F1NUX4-1", "A0A8V1A2E6-1", "E1BX69-1", "A0A8V0XPF0-1", "A0A8V0XFC9-1", "A0A8V0XBZ6-1", "A0A8V0ZRU7-1", "A0A8V0ZXD3-1", "A0A8V0YYI3-1", "A0A8V0YWW2-1", "A0A8V0YZP9-1", "A0A8V0YRJ8-1", "F1NLR7-1", "A0A8V0XCY6-1", "A0A8V1AMK9-1", "A0A8V0Z189-1", "P41239-1" ], "evidence": [ { "id": "10596", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/10596" } ] }, { "id": "R-GGA-1433418", "name": "Phosphorylation of JAK2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XHW1-1", "A0A8V0YNY4-1", "A0A8V0Z0R8-1", "A0A8V0ZDU6-1", "A0A3Q2U639-1", "P09324-1", "Q08156-1" ], "evidence": [ { "id": "R-GGA-1433418", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1433418" } ] }, { "id": "R-GGA-1433428", "name": "GRB2 is indirectly recruited to p-KIT through SHP2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XHW1-1", "Q90687-1", "A0A8V0Z0R8-1", "A0A8V0ZDU6-1", "A0A3Q2U639-1", "P09324-1", "Q08156-1" ], "evidence": [ { "id": "R-GGA-1433428", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1433428" } ] }, { "id": "R-GGA-1433451", "name": "JAK2 binds to p-KIT", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XHW1-1", "A0A8V0YNY4-1", "A0A8V0Z0R8-1", "A0A8V0ZDU6-1", "A0A3Q2U639-1", "P09324-1", "Q08156-1" ], "evidence": [ { "id": "R-GGA-1433451", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1433451" } ] }, { "id": "R-GGA-1433454", "name": "Phosphorylation of GAB2 by SFKs", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XHW1-1", "Q90687-1", "A0A8V0Z0R8-1", "A0A8V0ZDU6-1", "A0A3Q2U639-1", "P09324-1", "Q08156-1" ], "evidence": [ { "id": "R-GGA-1433454", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1433454" } ] }, { "id": "R-GGA-1433456", "name": "Recruitment of STATs", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XHW1-1", "A0A8V0YNY4-1", "A0A8V0Z0R8-1", "A0A8V0ZDU6-1", "A0A3Q2U639-1", "P09324-1", "Q08156-1" ], "evidence": [ { "id": "R-GGA-1433456", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1433456" } ] }, { "id": "R-GGA-1433488", "name": "Phosphorylation of SHP2 by SFKs", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XHW1-1", "Q90687-1", "A0A8V0Z0R8-1", "A0A8V0ZDU6-1", "A0A3Q2U639-1", "P09324-1", "Q08156-1" ], "evidence": [ { "id": "R-GGA-1433488", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1433488" } ] }, { "id": "R-GGA-1433506", "name": "Phosphorylation of APS", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XHW1-1", "A0A8V0Z0R8-1", "A0A8V0ZDU6-1", "A0A3Q2U639-1", "P09324-1", "Q08156-1" ], "evidence": [ { "id": "R-GGA-1433506", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1433506" } ] }, { "id": "R-GGA-1433514", "name": "Synthesis of PIP3 from PIP2 by PI3K", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XHW1-1", "Q90687-1", "A0A8V0Z0R8-1", "A0A8V0ZDU6-1", "A0A3Q2U639-1", "P09324-1", "Q08156-1" ], "evidence": [ { "id": "R-GGA-1433514", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1433514" } ] }, { "id": "R-GGA-1433542", "name": "Phosphorylation and activation of VAV1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [ "R-GGA-195066" ], "output_participant_list": [], "enzyme_list": [ "A0A8V0XHW1-1", "A0A8V0Z0R8-1", "A0A8V0ZDU6-1", "A0A3Q2U639-1", "P09324-1", "Q08156-1" ], "evidence": [ { "id": "R-GGA-1433542", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1433542" } ] }, { "id": "R-GGA-1470009", "name": "Phosphorylation of STATs", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XHW1-1", "A0A8V0YNY4-1", "A0A8V0Z0R8-1", "A0A8V0ZDU6-1", "A0A3Q2U639-1", "P09324-1", "Q08156-1" ], "evidence": [ { "id": "R-GGA-1470009", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1470009" } ] }, { "id": "R-GGA-1470010", "name": "Dimerization of STATs", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XHW1-1", "A0A8V0YNY4-1", "A0A8V0Z0R8-1", "A0A8V0ZDU6-1", "A0A3Q2U639-1", "P09324-1", "Q08156-1" ], "evidence": [ { "id": "R-GGA-1470010", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1470010" } ] }, { "id": "R-GGA-1470012", "name": "Disassociation and translocation of STATs to the nucleus", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, nucleoplasm, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XHW1-1", "A0A8V0YNY4-1", "A0A8V0Z0R8-1", "A0A8V0ZDU6-1", "A0A3Q2U639-1", "P09324-1", "Q08156-1" ], "evidence": [ { "id": "R-GGA-1470012", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1470012" } ] }, { "id": "R-GGA-1472121", "name": "Phosphorylation of p-KIT on Y900 by Src kinases", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XHW1-1", "A0A8V0Z0R8-1", "A0A8V0ZDU6-1", "A0A3Q2U639-1", "P09324-1", "Q08156-1" ], "evidence": [ { "id": "R-GGA-1472121", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1472121" } ] }, { "id": "R-GGA-1562641", "name": "Indirect recruitment of PI3K to KIT via p(Y)-GAB2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XHW1-1", "Q90687-1", "A0A8V0Z0R8-1", "A0A8V0ZDU6-1", "A0A3Q2U639-1", "P09324-1", "Q08156-1" ], "evidence": [ { "id": "R-GGA-1562641", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1562641" } ] }, { "id": "R-GGA-1963586", "name": "SRC family kinases phosphorylate ERBB2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XNF4-1", "A0A8V0ZXS7-1", "A0A8V1A7N1-1", "A0A8V0ZDU6-1", "A0A3Q2U639-1", "P09324-1", "A0A8V0YIT6-1" ], "evidence": [ { "id": "R-GGA-1963586", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1963586" } ] }, { "id": "R-GGA-205234", "name": "Indirect recruitment of GAB2 to p-KIT", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XHW1-1", "Q90687-1", "A0A8V0Z0R8-1", "A0A8V0ZDU6-1", "A0A3Q2U639-1", "P09324-1", "Q08156-1" ], "evidence": [ { "id": "R-GGA-205234", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-205234" } ] }, { "id": "R-GGA-205238", "name": "SHP2 interacts with p-KIT", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XHW1-1", "Q90687-1", "A0A8V0Z0R8-1", "A0A8V0ZDU6-1", "A0A3Q2U639-1", "P09324-1", "Q08156-1" ], "evidence": [ { "id": "R-GGA-205238", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-205238" } ] }, { "id": "R-GGA-205244", "name": "Recruitment of CBL to KIT", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XHW1-1", "A0A8V0ZY53-1", "A0A8V0Z0R8-1", "A0A8V0ZDU6-1", "A0A3Q2U639-1", "P09324-1", "Q08156-1" ], "evidence": [ { "id": "R-GGA-205244", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-205244" } ] }, { "id": "R-GGA-205319", "name": "Interaction of APS and p-KIT", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XHW1-1", "A0A8V0Z0R8-1", "A0A8V0ZDU6-1", "A0A3Q2U639-1", "P09324-1", "Q08156-1" ], "evidence": [ { "id": "R-GGA-205319", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-205319" } ] }, { "id": "R-GGA-210291", "name": "Phosphorylation of PECAM-1 by Fyn or Lyn or c-Src", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XHW1-1", "A0A8V0Z0R8-1", "A0A8V0ZDU6-1", "A0A3Q2U639-1", "P09324-1" ], "evidence": [ { "id": "R-GGA-210291", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-210291" } ] }, { "id": "R-GGA-2316434", "name": "PI3K phosphorylates PIP2 to PIP3", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q91044-1", "E1C093-1", "A0A8V0YHK2-1", "A0M8T9-1", "A0A8V0XB17-1", "A0A8V0YLC3-1", "A0A8V0Z7L6-1", "F1NCL8-1", "Q90687-1", "A0A8V0XNF4-1", "A0A8V0XQ80-1", "A0A8V0YCV8-1", "A0A8V0YYZ7-1", "A0A8V0ZE65-1", "A0A8V0ZXS7-1", "A0A8V1A7N1-1", "F1NHX1-1", "A0A8V0YZE5-1", "A0A8V0Z0R8-1", "A0A8V0Z8U4-1", "A0A8V0ZDU6-1", "A0A3Q2U639-1", "Q08156-1", "A0A8V0YIT6-1" ], "evidence": [ { "id": "R-GGA-2316434", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2316434" } ] }, { "id": "R-GGA-388814", "name": "Grb2 binds CD28", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0Z0R8-1", "A0A3Q2U639-1" ], "evidence": [ { "id": "R-GGA-388814", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-388814" } ] }, { "id": "R-GGA-388829", "name": "SHP2 phosphatase binds CTLA-4", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XHW1-1", "Q90687-1", "A0A8V0Z0R8-1", "A0A8V0ZDU6-1", "A0A3Q2U639-1", "P09324-1" ], "evidence": [ { "id": "R-GGA-388829", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-388829" } ] }, { "id": "R-GGA-388831", "name": "Phosphorylation of CD28", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XHW1-1", "A0A8V0Z0R8-1", "A0A8V0ZDU6-1", "A0A3Q2U639-1", "P09324-1" ], "evidence": [ { "id": "R-GGA-388831", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-388831" } ] }, { "id": "R-GGA-388832", "name": "PI3K binds CD28", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1C093-1", "F1NHX1-1", "A0A8V0Z0R8-1", "A0A3Q2U639-1" ], "evidence": [ { "id": "R-GGA-388832", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-388832" } ] }, { "id": "R-GGA-389158", "name": "CD28 bound PI3K phosphorylates PIP2 to PIP3", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1C093-1", "F1NHX1-1", "A0A8V0Z0R8-1", "A0A3Q2U639-1" ], "evidence": [ { "id": "R-GGA-389158", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-389158" } ] }, { "id": "R-GGA-389348", "name": "Activation of Rac1 by pVav1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0Z0R8-1", "A0A8V0Z8U4-1", "A0A3Q2U639-1" ], "evidence": [ { "id": "R-GGA-389348", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-389348" } ] }, { "id": "R-GGA-389350", "name": "Activation of Cdc42 by pVav1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0Z0R8-1", "A0A3Q2U639-1", "Q90694-1" ], "evidence": [ { "id": "R-GGA-389350", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-389350" } ] }, { "id": "R-GGA-389352", "name": "Translocation of Vav1 to CD28", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0Z0R8-1", "A0A3Q2U639-1" ], "evidence": [ { "id": "R-GGA-389352", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-389352" } ] }, { "id": "R-GGA-389354", "name": "Activation of Vav1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0Z0R8-1", "A0A3Q2U639-1" ], "evidence": [ { "id": "R-GGA-389354", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-389354" } ] }, { "id": "R-GGA-389381", "name": "Gads binds CD28", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0Z0R8-1", "A0A3Q2U639-1" ], "evidence": [ { "id": "R-GGA-389381", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-389381" } ] }, { "id": "R-GGA-392054", "name": "NCAM1:pFAK:Grb2:Sos-mediated nucleotide exchange of Ras", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YWD3-1", "Q5F352-1", "A0A3Q2U639-1", "P08642-1" ], "evidence": [ { "id": "R-GGA-392054", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-392054" } ] }, { "id": "R-GGA-3928604", "name": "SFKs phosphorylate VAV2,3", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XBZ6-1", "A0A8V0XFC9-1", "A0A8V0XHW1-1", "A0A8V0XPF0-1", "F1NJX6-1", "A0A8V0ZPH9-1", "A0A8V0ZXD3-1", "A0A8V0ZRU7-1", "A0A8V1A2E6-1", "A0A8V0YRJ8-1", "A0A8V0YUC4-1", "A0A8V0YYI3-1", "A0A8V0YZP9-1", "A0A8V0ZDU6-1", "A0A3Q2U639-1", "P09324-1" ], "evidence": [ { "id": "R-GGA-3928604", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3928604" } ] }, { "id": "R-GGA-3928607", "name": "p-EPHs bind VAV2,3", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XBZ6-1", "A0A8V0XFC9-1", "A0A8V0XHW1-1", "A0A8V0XPF0-1", "F1NJX6-1", "A0A8V0ZPH9-1", "A0A8V0ZXD3-1", "A0A8V0ZRU7-1", "A0A8V1A2E6-1", "A0A8V0YRJ8-1", "A0A8V0YUC4-1", "A0A8V0YYI3-1", "A0A8V0YZP9-1", "A0A8V0ZDU6-1", "A0A3Q2U639-1", "P09324-1" ], "evidence": [ { "id": "R-GGA-3928607", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3928607" } ] }, { "id": "R-GGA-3928614", "name": "EFNB:GRB4 binds GIT1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZRU7-1", "A0A8V1A2E6-1", "A0A8V0YUC4-1", "A0A8V0YZP9-1", "A0A8V0ZDU6-1", "A0A3Q2U639-1" ], "evidence": [ { "id": "R-GGA-3928614", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3928614" } ] }, { "id": "R-GGA-3928615", "name": "EFNBs bind SFKs", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZRU7-1", "A0A8V1A2E6-1", "A0A8V0YUC4-1", "A0A8V0YZP9-1", "A0A8V0ZDU6-1", "A0A3Q2U639-1" ], "evidence": [ { "id": "R-GGA-3928615", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3928615" } ] }, { "id": "R-GGA-3928625", "name": "PAKs autophosphorylate", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BS97-1", "E1C3P6-1", "A0A8V0ZRU7-1", "A0A8V1A2E6-1", "A0A8V0YUC4-1", "A0A8V0YYX2-1", "A0A8V0YZP9-1", "A0A8V0Z8U4-1", "A0A8V0ZDU6-1", "A0A3Q2U639-1" ], "evidence": [ { "id": "R-GGA-3928625", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3928625" } ] }, { "id": "R-GGA-3928627", "name": "EPHB phosphorylates TIAM1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XHW1-1", "A0A8V0ZRU7-1", "A0A8V1A2E6-1", "A0A8V0YUC4-1", "A0A8V0YZP9-1", "A0A8V0ZDU6-1", "A0A3Q2U639-1", "P09324-1" ], "evidence": [ { "id": "R-GGA-3928627", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3928627" } ] }, { "id": "R-GGA-3928628", "name": "VAV exchanges GTP for GDP on RAC1, activating it", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XBZ6-1", "A0A8V0XFC9-1", "A0A8V0XHW1-1", "A0A8V0XPF0-1", "F1NJX6-1", "A0A8V0ZPH9-1", "A0A8V0ZXD3-1", "A0A8V0ZRU7-1", "A0A8V1A2E6-1", "A0A8V0YRJ8-1", "A0A8V0YUC4-1", "A0A8V0YYI3-1", "A0A8V0YZP9-1", "A0A8V0Z8U4-1", "A0A8V0ZDU6-1", "A0A3Q2U639-1", "P09324-1" ], "evidence": [ { "id": "R-GGA-3928628", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3928628" } ] }, { "id": "R-GGA-3928631", "name": "GIT1 binds bPIX", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZRU7-1", "A0A8V1A2E6-1", "A0A8V0YUC4-1", "A0A8V0YZP9-1", "A0A8V0ZDU6-1", "A0A3Q2U639-1" ], "evidence": [ { "id": "R-GGA-3928631", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3928631" } ] }, { "id": "R-GGA-3928633", "name": "bPIX exchanges GTP for GDP on RAC, activating it", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZRU7-1", "A0A8V1A2E6-1", "A0A8V0YUC4-1", "A0A8V0YZP9-1", "A0A8V0Z8U4-1", "A0A8V0ZDU6-1", "A0A3Q2U639-1" ], "evidence": [ { "id": "R-GGA-3928633", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3928633" } ] }, { "id": "R-GGA-3928639", "name": "p-EFNB binds GRB4", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZRU7-1", "A0A8V1A2E6-1", "A0A8V0YUC4-1", "A0A8V0YZP9-1", "A0A8V0ZDU6-1", "A0A3Q2U639-1" ], "evidence": [ { "id": "R-GGA-3928639", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3928639" } ] }, { "id": "R-GGA-3928640", "name": "PAKs phosphorylate MLC", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [ "R-GGA-390735" ], "output_participant_list": [ "R-GGA-390749" ], "enzyme_list": [ "E1BS97-1", "E1C3P6-1", "A0A8V0ZRU7-1", "A0A8V1A2E6-1", "A0A8V0YUC4-1", "A0A8V0YYX2-1", "A0A8V0YZP9-1", "A0A8V0Z8U4-1", "A0A8V0ZDU6-1", "A0A3Q2U639-1" ], "evidence": [ { "id": "R-GGA-3928640", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3928640" } ] }, { "id": "R-GGA-3928641", "name": "PAK binds RAC and bPIX", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BS97-1", "E1C3P6-1", "A0A8V0ZRU7-1", "A0A8V1A2E6-1", "A0A8V0YUC4-1", "A0A8V0YYX2-1", "A0A8V0YZP9-1", "A0A8V0Z8U4-1", "A0A8V0ZDU6-1", "A0A3Q2U639-1" ], "evidence": [ { "id": "R-GGA-3928641", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3928641" } ] }, { "id": "R-GGA-3928642", "name": "TIAM1 exchanges GTP for GDP on RAC1, activating it", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XBZ6-1", "A0A8V0XFC9-1", "A0A8V0XHW1-1", "A0A8V0XPF0-1", "F1NJX6-1", "A0A8V0ZPH9-1", "A0A8V0ZXD3-1", "A0A8V0YRJ8-1", "A0A8V0YYI3-1", "A0A8V0Z8U4-1", "A0A8V0ZDU6-1", "A0A3Q2U639-1", "P09324-1" ], "evidence": [ { "id": "R-GGA-3928642", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3928642" } ] }, { "id": "R-GGA-3928645", "name": "EPHB:NMDAR binds TIAM1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XHW1-1", "A0A8V0ZRU7-1", "A0A8V1A2E6-1", "A0A8V0YUC4-1", "A0A8V0YZP9-1", "A0A8V0ZDU6-1", "A0A3Q2U639-1", "P09324-1" ], "evidence": [ { "id": "R-GGA-3928645", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3928645" } ] }, { "id": "R-GGA-3928651", "name": "NGEF exchanges GTP for GDP on RHOA", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XBZ6-1", "A0A8V0XFC9-1", "A0A8V0XHW1-1", "A0A8V0XPF0-1", "F1NJX6-1", "A0A8V0ZPH9-1", "A0A8V0ZXD3-1", "A0A8V0YRJ8-1", "A0A8V0YYI3-1", "A0A8V0ZDU6-1", "A0A3Q2U639-1", "P09324-1" ], "evidence": [ { "id": "R-GGA-3928651", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3928651" } ] }, { "id": "R-GGA-399930", "name": "Activation of PAK by Rac1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0X6E7-1", "E1BS97-1", "E1C3P6-1", "A0A8V0YYX2-1", "A0A8V0Z8U4-1", "A0A3Q2U639-1" ], "evidence": [ { "id": "R-GGA-399930", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-399930" } ] }, { "id": "R-GGA-399933", "name": "Sema3A binds Nrp-1 bound to PlexinA", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q2U639-1" ], "evidence": [ { "id": "R-GGA-399933", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-399933" } ] }, { "id": "R-GGA-399939", "name": "Autophosphorylation of PAK", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0X6E7-1", "E1BS97-1", "E1C3P6-1", "A0A8V0YYX2-1", "A0A8V0Z8U4-1", "A0A3Q2U639-1" ], "evidence": [ { "id": "R-GGA-399939", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-399939" } ] }, { "id": "R-GGA-399944", "name": "Phosphorylation of CRMPs by Cdk5", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q2U639-1" ], "evidence": [ { "id": "R-GGA-399944", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-399944" } ] }, { "id": "R-GGA-399947", "name": "Tyrosine phosphorylation of CRMPs by Fes", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0X6E7-1", "A0A3Q2U639-1" ], "evidence": [ { "id": "R-GGA-399947", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-399947" } ] }, { "id": "R-GGA-399951", "name": "Phosphorylation of CRMPs by GSK3beta", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V1A637-1", "A0A3Q2U639-1" ], "evidence": [ { "id": "R-GGA-399951", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-399951" } ] }, { "id": "R-GGA-399952", "name": "Phosphorylation of LIMK-1 by PAK", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0X6E7-1", "E1BS97-1", "E1C3P6-1", "A0A8V0YYX2-1", "A0A8V0Z8U4-1", "A0A3Q2U639-1", "Q8QFP8-1" ], "evidence": [ { "id": "R-GGA-399952", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-399952" } ] }, { "id": "R-GGA-4093327", "name": "EPHA binds TIAM1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XBZ6-1", "A0A8V0XFC9-1", "A0A8V0XHW1-1", "A0A8V0XPF0-1", "F1NJX6-1", "A0A8V0ZPH9-1", "A0A8V0ZXD3-1", "A0A8V0YRJ8-1", "A0A8V0YYI3-1", "A0A8V0ZDU6-1", "A0A3Q2U639-1", "P09324-1" ], "evidence": [ { "id": "R-GGA-4093327", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4093327" } ] }, { "id": "R-GGA-4093336", "name": "p-TIAM1 exchanges GTP for GDP on RAC1, activating it", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XHW1-1", "A0A8V0ZRU7-1", "A0A8V1A2E6-1", "A0A8V0YUC4-1", "A0A8V0YZP9-1", "A0A8V0Z8U4-1", "A0A8V0ZDU6-1", "A0A3Q2U639-1", "P09324-1" ], "evidence": [ { "id": "R-GGA-4093336", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4093336" } ] }, { "id": "R-GGA-5218804", "name": "p38 MAPK activation by VEGFR", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V1ACB5-1", "E1BS97-1", "A0A8V0X2Y2-1", "A0A1D5PIQ5-1", "A0A3Q2U639-1", "F1NW21-1", "Q90694-1" ], "evidence": [ { "id": "R-GGA-5218804", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5218804" } ] }, { "id": "R-GGA-5218806", "name": "FYN autophosphorylates", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q2U639-1", "F1NW21-1" ], "evidence": [ { "id": "R-GGA-5218806", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5218806" } ] }, { "id": "R-GGA-5218812", "name": "FYN phosphorylates PAK2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BS97-1", "A0A3Q2U639-1", "F1NW21-1", "Q90694-1" ], "evidence": [ { "id": "R-GGA-5218812", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5218812" } ] }, { "id": "R-GGA-5218814", "name": "PAK2 autophorylates", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BS97-1", "A0A3Q2U639-1", "F1NW21-1", "Q90694-1" ], "evidence": [ { "id": "R-GGA-5218814", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5218814" } ] }, { "id": "R-GGA-5218824", "name": "p-6Y-VEGFR2 binds FYN", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q2U639-1", "F1NW21-1" ], "evidence": [ { "id": "R-GGA-5218824", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5218824" } ] }, { "id": "R-GGA-5218832", "name": "CDC42:GTP binds PAK2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BS97-1", "A0A3Q2U639-1", "F1NW21-1", "Q90694-1" ], "evidence": [ { "id": "R-GGA-5218832", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5218832" } ] }, { "id": "R-GGA-5218847", "name": "PAK2 binds NCK", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BS97-1", "A0A3Q2U639-1", "F1NW21-1" ], "evidence": [ { "id": "R-GGA-5218847", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5218847" } ] }, { "id": "R-GGA-532603", "name": "Nephrin mediated activation of N-WASP", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q2U639-1" ], "evidence": [ { "id": "R-GGA-532603", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-532603" } ] }, { "id": "R-GGA-5624486", "name": "SFKs phosphorylates RAF1 on Y340,Y341", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XHW1-1", "Q5F352-1", "A0A3Q2U639-1", "P05625-1", "P08642-1" ], "evidence": [ { "id": "R-GGA-5624486", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5624486" } ] }, { "id": "R-GGA-5672965", "name": "RAS GEFs promote RAS nucleotide exchange", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XB58-1", "F1P011-1", "A0M8T9-1", "A0A8V0XB17-1", "A0A8V0YLC3-1", "A0A8V0YWD3-1", "A0A8V0Z7L6-1", "F1NCL8-1", "Q5F352-1", "A0A8V0XNF4-1", "A0A8V0XQ80-1", "A0A8V0YGR1-1", "A0A8V0YNY4-1", "A0A8V0YYZ7-1", "A0A8V0ZXS7-1", "A0A8V1A7N1-1", "A0A8V0YZE5-1", "A0A8V0ZB33-1", "A0A3Q2U639-1", "A0A3Q2UKD3-1", "P08642-1", "Q08156-1", "A0A8V0YIT6-1" ], "evidence": [ { "id": "R-GGA-5672965", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5672965" } ] }, { "id": "R-GGA-879917", "name": "CBL, GRB2, FYN and PI3K p85 subunit are constitutively associated", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XHW1-1", "A0A8V0ZY53-1", "F1NHX1-1", "A0A8V0YT43-1", "A0A3Q2U639-1", "F1N9Y5-1", "P09324-1" ], "evidence": [ { "id": "R-GGA-879917", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-879917" } ] }, { "id": "R-GGA-8855237", "name": "FYN phosphorylates DAB1 in RELN:VLDLR:DAB1:SH3KBP1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q2U639-1" ], "evidence": [ { "id": "R-GGA-8855237", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8855237" } ] }, { "id": "R-GGA-9032798", "name": "DOCK3 activates RAC1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YCV8-1", "A0A8V0Z8U4-1", "A0A3Q2U639-1" ], "evidence": [ { "id": "R-GGA-9032798", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9032798" } ] }, { "id": "R-GGA-912627", "name": "CBL ubiquitinates PI3K", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XHW1-1", "A0A8V0ZY53-1", "F1NHX1-1", "A0A8V0YT43-1", "A0A3Q2U639-1", "F1N9Y5-1", "P09324-1" ], "evidence": [ { "id": "R-GGA-912627", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-912627" } ] }, { "id": "R-GGA-9934751", "name": "CDH1 is phosphorylated on tyrosine residues", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [ "R-GGA-191697" ], "enzyme_list": [ "A0A8V0ZDU6-1", "A0A3Q2U639-1" ], "evidence": [ { "id": "R-GGA-9934751", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9934751" } ] } ], "reaction_participants": [ { "participant_id": "R-GGA-191697", "participant_name": "CTNNA1 [cytosol]", "crossref": [ { "id": "ENSGALT00010020065", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALG00010008385", "database": "ENSEMBL", "url": "" }, { "id": "A0A8V0XTR4", "database": "UniProt", "url": "" }, { "id": "ENSGALP00010011614", "database": "ENSEMBL", "url": "" } ] }, { "participant_id": "R-GGA-195066", "participant_name": "LOC107050724 [cytosol]", "crossref": [ { "id": "A0A8V0XJF3", "database": "UniProt", "url": "" }, { "id": "ENSGALG00010003064", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALP00010004390", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALT00010007334", "database": "ENSEMBL", "url": "" } ] }, { "participant_id": "R-GGA-390735", "participant_name": "MYL12A [cytosol]", "crossref": [ { "id": "A0A8V0XAJ5", "database": "UniProt", "url": "" }, { "id": "ENSGALG00010001297", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALP00010001539", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALT00010003003", "database": "ENSEMBL", "url": "" } ] }, { "participant_id": "R-GGA-390749", "participant_name": "phospho-MYL12A [cytosol]", "crossref": [ { "id": "ENSGALG00010001297", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALT00010003003", "database": "ENSEMBL", "url": "" }, { "id": "A0A8V0XAJ5", "database": "UniProt", "url": "" }, { "id": "ENSGALP00010001539", "database": "ENSEMBL", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5PD64", "gene_name": "MAP2K3", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PD64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PD64" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A1D5PD64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PD64" } ] } ] }, { "uniprot_ac": "A0A1D5PIQ5", "gene_name": "MAPK14", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PIQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PIQ5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A1D5PIQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PIQ5" } ] } ] }, { "uniprot_ac": "A0A3Q2U1T2", "gene_name": "BLK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2U1T2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U1T2" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A3Q2U1T2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U1T2" } ] } ] }, { "uniprot_ac": "A0A3Q2U639", "gene_name": "FYN", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2U639", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U639" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A3Q2U639", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U639" } ] } ] }, { "uniprot_ac": "A0A3Q2UKD3", "gene_name": "TEK", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2UKD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UKD3" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A3Q2UKD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UKD3" } ] } ] }, { "uniprot_ac": "A0A8V0X2Y2", "gene_name": "MAPK12", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X2Y2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X2Y2" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0X2Y2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X2Y2" } ] } ] }, { "uniprot_ac": "A0A8V0X5W9", "gene_name": "TYK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X5W9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X5W9" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0X5W9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X5W9" } ] } ] }, { "uniprot_ac": "A0A8V0X6E7", "gene_name": "FES", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X6E7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X6E7" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0X6E7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X6E7" } ] } ] }, { "uniprot_ac": "A0A8V0XB17", "gene_name": "FGFR2", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XB17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XB17" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0XB17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XB17" } ] } ] }, { "uniprot_ac": "A0A8V0XB58", "gene_name": "CAMK2D", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XB58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XB58" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V0XB58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XB58" } ] } ] }, { "uniprot_ac": "A0A8V0XBZ6", "gene_name": "EPHA7", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XBZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XBZ6" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0XBZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XBZ6" } ] } ] }, { "uniprot_ac": "A0A8V0XCY6", "gene_name": "TTK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XCY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCY6" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V0XCY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCY6" } ] } ] }, { "uniprot_ac": "A0A8V0XFC9", "gene_name": "EPHA5", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XFC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFC9" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0XFC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFC9" } ] } ] }, { "uniprot_ac": "A0A8V0XHW1", "gene_name": "LYN", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XHW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XHW1" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0XHW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XHW1" } ] } ] }, { "uniprot_ac": "A0A8V0XN86", "gene_name": "MUSK", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XN86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XN86" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0XN86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XN86" } ] } ] }, { "uniprot_ac": "A0A8V0XNF4", "gene_name": "EGFR", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XNF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNF4" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0XNF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNF4" } ] } ] }, { "uniprot_ac": "A0A8V0XPF0", "gene_name": "EPHA6", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XPF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XPF0" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0XPF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XPF0" } ] } ] }, { "uniprot_ac": "A0A8V0XQ80", "gene_name": "FLT3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQ80", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ80" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0XQ80", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ80" } ] } ] }, { "uniprot_ac": "A0A8V0XQG0", "gene_name": "FLT1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQG0" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0XQG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQG0" } ] } ] }, { "uniprot_ac": "A0A8V0XZ82", "gene_name": "PTK2B", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] 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"evidence": [ { "id": "A0A8V0YHK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHK2" } ] } ] }, { "uniprot_ac": "A0A8V0YIT6", "gene_name": "ERBB4", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YIT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIT6" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0YIT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIT6" } ] } ] }, { "uniprot_ac": "A0A8V0YIV6", "gene_name": "DYRK1A", "activity": [ { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] } ] }, { "uniprot_ac": "A0A8V0YJJ1", "gene_name": "ITK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YJJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJJ1" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0YJJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJJ1" } ] } ] }, { "uniprot_ac": "A0A8V0YKP8", "gene_name": "VEGFRKDRL", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YKP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKP8" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0YKP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKP8" } ] } ] }, { "uniprot_ac": "A0A8V0YLC3", "gene_name": "PDGFRA", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YLC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLC3" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0YLC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLC3" } ] } ] }, { "uniprot_ac": "A0A8V0YNY4", "gene_name": "JAK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YNY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNY4" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0YNY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNY4" } ] } ] }, { "uniprot_ac": "A0A8V0YPR4", "gene_name": "DDR2", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YPR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPR4" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0YPR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPR4" } ] } ] }, { "uniprot_ac": "A0A8V0YRJ8", "gene_name": "EPHA10", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRJ8" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0YRJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRJ8" } ] } ] }, { "uniprot_ac": "A0A8V0YT43", "gene_name": "HCK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YT43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YT43" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0YT43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YT43" } ] } ] }, { "uniprot_ac": "A0A8V0YUC4", "gene_name": "EPHB3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", 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"url": "https://www.uniprot.org/uniprotkb/A0A8V0YW12" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0YW12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YW12" } ] } ] }, { "uniprot_ac": "A0A8V0YWD3", "gene_name": "PTPRA", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0YWD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YWD3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0YWD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YWD3" } ] } ] }, { "uniprot_ac": "A0A8V0YWW2", "gene_name": "EPHA2", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YWW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YWW2" } ] 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"uniprot_ac": "A0A8V0YZ74", "gene_name": "MAP2K5", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZ74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZ74" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V0YZ74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZ74" } ] } ] }, { "uniprot_ac": "A0A8V0YZE5", "gene_name": "PDGFRB", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZE5" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0YZE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZE5" } ] } ] }, { "uniprot_ac": "A0A8V0YZP9", "gene_name": "EPHB2", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZP9" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0YZP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZP9" } ] } ] }, { "uniprot_ac": "A0A8V0Z0R8", "gene_name": "LCK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z0R8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0R8" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0Z0R8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0R8" } ] } ] }, { "uniprot_ac": "A0A8V0Z189", "gene_name": "PKDCCA", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z189", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z189" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0Z189", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z189" } ] } ] }, { "uniprot_ac": "A0A8V0Z3S3", "gene_name": "ALK", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z3S3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3S3" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0Z3S3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3S3" } ] } ] }, { "uniprot_ac": "A0A8V0Z4B2", "gene_name": "MERTK", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z4B2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4B2" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0Z4B2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4B2" } ] } ] }, { "uniprot_ac": "A0A8V0Z7L6", "gene_name": "FGFR1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z7L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7L6" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0Z7L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7L6" } ] } ] }, { "uniprot_ac": "A0A8V0Z8U4", "gene_name": "RAC1", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0Z8U4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8U4" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0Z8U4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8U4" } ] } ] }, { "uniprot_ac": "A0A8V0ZB33", "gene_name": "CAMK2G", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZB33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB33" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V0ZB33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB33" } ] } ] }, { "uniprot_ac": "A0A8V0ZBN6", "gene_name": "MAP2K1", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZBN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBN6" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V0ZBN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBN6" } ] } ] }, { "uniprot_ac": "A0A8V0ZC34", "gene_name": "AXL", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZC34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC34" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0ZC34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC34" } ] } ] }, { "uniprot_ac": "A0A8V0ZDU6", "gene_name": "SRC", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZDU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDU6" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0ZDU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDU6" } ] } ] }, { "uniprot_ac": "A0A8V0ZE65", "gene_name": "NTRK3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZE65", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE65" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0ZE65", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE65" } ] } ] }, { "uniprot_ac": "A0A8V0ZER1", "gene_name": "IGF1R", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZER1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZER1" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0ZER1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZER1" } ] } ] }, { "uniprot_ac": "A0A8V0ZND5", "gene_name": "CSK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZND5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZND5" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0ZND5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZND5" } ] } ] }, { "uniprot_ac": "A0A8V0ZP30", "gene_name": "LTK", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZP30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP30" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0ZP30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP30" } ] } ] }, { "uniprot_ac": "A0A8V0ZPH9", "gene_name": "EPHA1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZPH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPH9" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0ZPH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPH9" } ] } ] }, { "uniprot_ac": "A0A8V0ZRU7", "gene_name": "EPHB6", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZRU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRU7" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0ZRU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRU7" } ] } ] }, { "uniprot_ac": "A0A8V0ZSN8", "gene_name": "JAK1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZSN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSN8" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0ZSN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSN8" } ] } ] }, { "uniprot_ac": "A0A8V0ZWV8", "gene_name": "TIE1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZWV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWV8" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0ZWV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWV8" } ] } ] }, { "uniprot_ac": "A0A8V0ZXD3", "gene_name": "EPHA4", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZXD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXD3" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0ZXD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXD3" } ] } ] }, { "uniprot_ac": "A0A8V0ZXS7", "gene_name": "ERBB2", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZXS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXS7" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0ZXS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXS7" } ] } ] }, { "uniprot_ac": "A0A8V0ZY53", "gene_name": "CBL", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZY53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZY53" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZY53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZY53" } ] } ] }, { "uniprot_ac": "A0A8V1A069", "gene_name": "TESK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A069", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A069" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1A069", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A069" } ] } ] }, { "uniprot_ac": "A0A8V1A2E6", "gene_name": "EPHB1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A2E6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2E6" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V1A2E6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2E6" } ] } ] }, { "uniprot_ac": "A0A8V1A3N1", "gene_name": "MST1R", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A3N1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3N1" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V1A3N1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3N1" } ] } ] }, { "uniprot_ac": "A0A8V1A637", "gene_name": "GSK3A", "activity": [ { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A637", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A637" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A8V1A637", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A637" } ] } ] }, { "uniprot_ac": "A0A8V1A7E0", "gene_name": "DYRK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1A7E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E0" } ] } ] }, { "uniprot_ac": "A0A8V1A7N1", "gene_name": "ERBB3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7N1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7N1" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V1A7N1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7N1" } ] } ] }, { "uniprot_ac": "A0A8V1A9R2", "gene_name": "JAK3", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A9R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9R2" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V1A9R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9R2" } ] } ] }, { "uniprot_ac": "A0A8V1ABP4", "gene_name": "DSTYK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP4" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1ABP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP4" } ] } ] }, { "uniprot_ac": "A0A8V1ACB5", "gene_name": "MAPK13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACB5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1ACB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACB5" } ] } ] }, { "uniprot_ac": "A0A8V1ACF7", "gene_name": "ABL1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF7" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V1ACF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF7" } ] } ] }, { "uniprot_ac": "A0A8V1ADF0", "gene_name": "MAP2K2", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF0" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V1ADF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF0" } ] } ] }, { "uniprot_ac": "A0A8V1AEL3", "gene_name": "ZAP70", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AEL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEL3" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V1AEL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEL3" } ] } ] }, { "uniprot_ac": "A0A8V1AFM7", "gene_name": "INSR", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AFM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFM7" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V1AFM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFM7" } ] } ] }, { "uniprot_ac": "A0A8V1AKW4", "gene_name": "MAP2K4", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AKW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKW4" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V1AKW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKW4" } ] } ] }, { "uniprot_ac": "A0A8V1AMK9", "gene_name": "BAZ1B", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AMK9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK9" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V1AMK9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK9" } ] } ] }, { "uniprot_ac": "A0M8T9", "gene_name": "MET", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0M8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0M8T9" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0M8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0M8T9" } ] } ] }, { "uniprot_ac": "E1BS97", "gene_name": "PAK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BS97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BS97" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BS97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BS97" } ] } ] }, { "uniprot_ac": "E1BTE1", "gene_name": "WEE2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BTE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BTE1" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "E1BTE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BTE1" } ] } ] }, { "uniprot_ac": "E1BTT3", "gene_name": "BMX", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BTT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BTT3" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "E1BTT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BTT3" } ] } ] }, { "uniprot_ac": "E1BX69", "gene_name": "EIF2AK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BX69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BX69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BX69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BX69" } ] } ] }, { "uniprot_ac": "E1C093", "gene_name": "PIK3CG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] } ] }, { "uniprot_ac": "E1C2C8", "gene_name": "MATK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C2C8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2C8" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "E1C2C8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2C8" } ] } ] }, { "uniprot_ac": "E1C3P6", "gene_name": "PAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C3P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C3P6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C3P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C3P6" } ] } ] }, { "uniprot_ac": "E1C7Z1", "gene_name": "FER", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C7Z1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C7Z1" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "E1C7Z1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C7Z1" } ] } ] }, { "uniprot_ac": "F1N996", "gene_name": "PTK6", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N996", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N996" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F1N996", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N996" } ] } ] }, { "uniprot_ac": "F1N9Y5", "gene_name": "SYK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N9Y5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N9Y5" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F1N9Y5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N9Y5" } ] } ] }, { "uniprot_ac": "F1NCL8", "gene_name": "FGFR4", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NCL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCL8" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1NCL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCL8" } ] } ] }, { "uniprot_ac": "F1NHX1", "gene_name": "PIK3CD", "activity": [ { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "F1NHX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NHX1" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "F1NHX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NHX1" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "F1NHX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NHX1" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "F1NHX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NHX1" } ] } ] }, { "uniprot_ac": "F1NJX6", "gene_name": "EPHA3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NJX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJX6" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1NJX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJX6" } ] } ] }, { "uniprot_ac": "F1NLR7", "gene_name": "CLK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NLR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLR7" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "F1NLR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLR7" } ] } ] }, { "uniprot_ac": "F1NQL9", "gene_name": "ROS1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NQL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NQL9" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1NQL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NQL9" } ] } ] }, { "uniprot_ac": "F1NUX4", "gene_name": "MTOR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NUX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NUX4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NUX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NUX4" } ] } ] }, { "uniprot_ac": "F1NVF2", "gene_name": "MAP2K6", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NVF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVF2" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "F1NVF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVF2" } ] } ] }, { "uniprot_ac": "F1NW21", "gene_name": "KDR", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NW21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NW21" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1NW21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NW21" } ] } ] }, { "uniprot_ac": "F1NZY8", "gene_name": "TEC", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NZY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NZY8" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F1NZY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NZY8" } ] } ] }, { "uniprot_ac": "F1P011", "gene_name": "CAMK2A", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1P011", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P011" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F1P011", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P011" } ] } ] }, { "uniprot_ac": "H9KZZ1", "gene_name": "NTRK1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "H9KZZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H9KZZ1" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "H9KZZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H9KZZ1" } ] } ] }, { "uniprot_ac": "H9KZZ2", "gene_name": "INSRR", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "H9KZZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H9KZZ2" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "H9KZZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H9KZZ2" } ] } ] }, { "uniprot_ac": "O42422", "gene_name": "EPHA7", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "O42422", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O42422" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "O42422", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O42422" } ] } ] }, { "uniprot_ac": "P00523", "gene_name": "SRC", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "P00523", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00523" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "P00523", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00523" } ] } ] }, { "uniprot_ac": "P05625", "gene_name": "RAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05625", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05625" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P05625", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05625" } ] } ] }, { "uniprot_ac": "P08642", "gene_name": "HRAS", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "P08642", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P08642" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "P08642", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P08642" } ] } ] }, { "uniprot_ac": "P08941", "gene_name": "ROS1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "P08941", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P08941" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "P08941", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P08941" } ] } ] }, { "uniprot_ac": "P09324", "gene_name": "YES1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "P09324", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P09324" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "P09324", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P09324" } ] } ] }, { "uniprot_ac": "P13387", "gene_name": "EGFR", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "P13387", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13387" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "P13387", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13387" } ] } ] }, { "uniprot_ac": "P18460", "gene_name": "FGFR3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "P18460", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18460" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "P18460", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18460" } ] } ] }, { "uniprot_ac": "P18461", "gene_name": "FGFR2", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "P18461", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18461" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "P18461", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18461" } ] } ] }, { "uniprot_ac": "P21804", "gene_name": "FGFR1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "P21804", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21804" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "P21804", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21804" } ] } ] }, { "uniprot_ac": "P28693", "gene_name": "EPHB2", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "P28693", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P28693" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "P28693", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P28693" } ] } ] }, { "uniprot_ac": "P29318", "gene_name": "EPHA3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "P29318", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P29318" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "P29318", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P29318" } ] } ] }, { "uniprot_ac": "P41239", "gene_name": "CSK", "activity": [ { "ec_number": "2.7.10.4", "activity": "ATP + [a protein]-(L-tyrosine) = ADP + [a protein]-(L-tyrosine)-phosphate. The optimal peptide substrate contains the sequence (relative to the phosphorylated tyrosine): Glu-Glu-Asp/Glu-Ile-Tyr-Phe-Phe-Phe-Phe. Physiological substrates are C-terminal tail of Src-family protein kinases.", "evidence": [ { "id": "P41239", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P41239" } ] }, { "ec_number": "2.7.10.4", "activity": "", "evidence": [ { "id": "P41239", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P41239" } ] } ] }, { "uniprot_ac": "P42683", "gene_name": "LCK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "P42683", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P42683" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "P42683", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P42683" } ] } ] }, { "uniprot_ac": "P54755", "gene_name": "EPHA5", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "P54755", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P54755" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "P54755", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P54755" } ] } ] }, { "uniprot_ac": "Q00944", "gene_name": "PTK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q00944", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q00944" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "Q00944", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q00944" } ] } ] }, { "uniprot_ac": "Q02977", "gene_name": "YRK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q02977", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q02977" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "Q02977", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q02977" } ] } ] }, { "uniprot_ac": "Q05876", "gene_name": "FYN", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q05876", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q05876" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "Q05876", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q05876" } ] } ] }, { "uniprot_ac": "Q07494", "gene_name": "EPHB1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q07494", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q07494" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "Q07494", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q07494" } ] } ] }, { "uniprot_ac": "Q07496", "gene_name": "EPHA4", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q07496", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q07496" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "Q07496", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q07496" } ] } ] }, { "uniprot_ac": "Q07497", "gene_name": "EPHB5", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q07497", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q07497" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "Q07497", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q07497" } ] } ] }, { "uniprot_ac": "Q07498", "gene_name": "EPHB3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q07498", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q07498" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "Q07498", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q07498" } ] } ] }, { "uniprot_ac": "Q08156", "gene_name": "KIT", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q08156", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08156" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "Q08156", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08156" } ] } ] }, { "uniprot_ac": "Q5F352", "gene_name": "NRAS", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "Q5F352", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F352" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "Q5F352", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F352" } ] } ] }, { "uniprot_ac": "Q5ZIU3", "gene_name": "DYRK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5ZIU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZIU3" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q5ZIU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZIU3" } ] } ] }, { "uniprot_ac": "Q6XUX0", "gene_name": "DSTYK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q6XUX0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6XUX0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q6XUX0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6XUX0" } ] } ] }, { "uniprot_ac": "Q75R65", "gene_name": "JAK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q75R65", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q75R65" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "Q75R65", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q75R65" } ] } ] }, { "uniprot_ac": "Q8AXY6", "gene_name": "MUSK", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q8AXY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8AXY6" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "Q8AXY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8AXY6" } ] } ] }, { "uniprot_ac": "Q8JH64", "gene_name": "BTK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q8JH64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8JH64" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "Q8JH64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8JH64" } ] } ] }, { "uniprot_ac": "Q8QFP8", "gene_name": "LIMK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q8QFP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8QFP8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8QFP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8QFP8" } ] } ] }, { "uniprot_ac": "Q8QHL3", "gene_name": "FLT1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q8QHL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8QHL3" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "Q8QHL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8QHL3" } ] } ] }, { "uniprot_ac": "Q90687", "gene_name": "PTPN11", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q90687", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q90687" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q90687", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q90687" } ] } ] }, { "uniprot_ac": "Q90694", "gene_name": "CDC42", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "Q90694", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q90694" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "Q90694", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q90694" } ] } ] }, { "uniprot_ac": "Q90891", "gene_name": "MAP2K2", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q90891", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q90891" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "Q90891", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q90891" } ] } ] }, { "uniprot_ac": "Q91009", "gene_name": "NTRK1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q91009", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q91009" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "Q91009", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q91009" } ] } ] }, { "uniprot_ac": "Q91044", "gene_name": "NTRK3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q91044", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q91044" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "Q91044", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q91044" } ] } ] }, { "uniprot_ac": "Q91987", "gene_name": "NTRK2", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q91987", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q91987" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "Q91987", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q91987" } ] } ] }, { "uniprot_ac": "Q98949", "gene_name": "TYRO3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q98949", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q98949" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "Q98949", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q98949" } ] } ] }, { "uniprot_ac": "Q9PUF6", "gene_name": "PDGFRA", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q9PUF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9PUF6" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "Q9PUF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9PUF6" } ] } ] }, { "uniprot_ac": "R4GJB8", "gene_name": "TESK1", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "R4GJB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GJB8" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "R4GJB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GJB8" } ] } ] }, { "uniprot_ac": "R4GJW5", "gene_name": "WEE1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "R4GJW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GJW5" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "R4GJW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GJW5" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A3Q2U639-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 589, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A3Q2U639-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A3Q2U639" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.7.10.2", "ec_name": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "2.7.10.2", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2" }, { "id": "2.7.10.2", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.7.10.2" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 113, "end_pos": 115 }, { "start_pos": 296, "end_pos": 298 }, { "start_pos": 303, "end_pos": 305 }, { "start_pos": 68, "end_pos": 70 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A3Q2U6I3-1", "uniprot_ac": "A0A3Q2U6I3", "uniprot_id": "A0A3Q2U6I3_CHICK", "mass": { "chemical_mass": 59329.0, "monoisotopic_mass": 59329.0 }, "refseq": { "ac": "XP_425011", "name": "excitatory amino acid transporter 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_425011" }, "gene_names": [ { "name": "SLC1A3", "type": "recommended", "evidence": [ { "id": "A0A3Q2U6I3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U6I3" } ] }, { "name": "SLC1A3", "type": "synonym", "evidence": [ { "id": "XP_425011", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_425011" } ] } ], "protein_names": [ { "name": "Amino acid transporter", "type": "recommended", "evidence": [ { "id": "A0A3Q2U6I3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U6I3/entry#names_and_taxonomy" } ] }, { "name": "excitatory amino acid transporter 1", "type": "synonym", "evidence": [ { "id": "XP_425011", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_425011" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052572.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Nov 16, 2006 this sequence version replaced XP_425011.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_425011", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_425011" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U6I3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U6I3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SLC1A3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U6I3", "locus": { "chromosome": "Z", "start_pos": 11786641, "end_pos": 11722286, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013632", "url": "https://www.ensembl.org/id/ENSGALG00010013632" } ] } } ], "crossref": [ { "id": "A0A3Q2U6I3", "url": "https://alphafold.ebi.ac.uk/entry/A0A3Q2U6I3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000003582", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000003582", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "395443", "url": "https://www.ncbi.nlm.nih.gov/gene/395443", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001991", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001991", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018107", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018107", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036458", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036458", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050746", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050746", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "VDWFMGI", "url": "https://omabrowser.org/oma/group/VDWFMGI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2U6I3", "url": "https://www.orthodb.org/?gene=A0A3Q2U6I3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YLD1", "url": "https://www.orthodb.org/?gene=A0A8V0YLD1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YLD6", "url": "https://www.orthodb.org/?gene=A0A8V0YLD6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YLE1", "url": "https://www.orthodb.org/?gene=A0A8V0YLE1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11958", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11958", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11958:SF24", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11958:SF24", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00375", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00375", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-210455", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-210455", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-210500", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-210500", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9958863", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9958863", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_425011", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_425011", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "70699", "url": "https://www.rhea-db.org/rhea/70699", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "70851", "url": "https://www.rhea-db.org/rhea/70851", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "71379", "url": "https://www.rhea-db.org/rhea/71379", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q2U6I3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U6I3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2U6I3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U6I3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLD1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLD1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLD1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLD1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLD6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLD6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLD6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLD6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLE1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLE1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLE1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLE1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTKGNGEDPKTGSRMERFQQGVRKRTLLAKKKVQSITRDDVKSYLLRNAFVLFTVVAVILGVILGFSLRSYKMSYREVKYFSFPGELLMRMLQMLVLPLIVSSLVTGIAALDSKASGKMGVRAVVYYMSTTIIAVLIGIIIVVIIHPGKGTKENMHREGKIVQVTAADAFLDLIRNMFPPNLVEACFKQFKTNYEKRMFKVDIPSNDTSTVASIISNVSAAVETLTQMREEMVPVPGSVNGVNALGLVVFSISFGLVIGSMKEQGQALKDFFDSLNEAIMRLVALIMWYAPLGILFLIAGKIVEMEDMGVIGGQLAMYTVTVIIGLLIHAVIVLPLLYFLITRKNPWVFIGGLIQALVTALGTSSSSATLPVTFKCLEEINGVDKRVTRFVLPVGATINMDGTALYEALAAIFIAQVNNFDLNFGQIITISITATAASIGAAGIPQAGLVTMVIVLTSVGLPTDDITLIIAVDWFLDRLRTTTNVLGDSIGAGIVEHLSRHELKNRDAEMGNSVIEENEMKKPYQLISQENESEKPLDSETKM", "length": 543, "header": "tr|A0A3Q2U6I3-1|A0A3Q2U6I3_CHICK Isoform 1 of Amino acid transporter OS=Gallus gallus OX=9031 GN=SLC1A3 PE=3 SV=1 CANONICAL=A0A3Q2U6I3-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2U6I3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U6I3/entry#A0A3Q2U6I3-1", "sequence": { "sequence": "MTKGNGEDPKTGSRMERFQQGVRKRTLLAKKKVQSITRDDVKSYLLRNAFVLFTVVAVILGVILGFSLRSYKMSYREVKYFSFPGELLMRMLQMLVLPLIVSSLVTGIAALDSKASGKMGVRAVVYYMSTTIIAVLIGIIIVVIIHPGKGTKENMHREGKIVQVTAADAFLDLIRNMFPPNLVEACFKQFKTNYEKRMFKVDIPSNDTSTVASIISNVSAAVETLTQMREEMVPVPGSVNGVNALGLVVFSISFGLVIGSMKEQGQALKDFFDSLNEAIMRLVALIMWYAPLGILFLIAGKIVEMEDMGVIGGQLAMYTVTVIIGLLIHAVIVLPLLYFLITRKNPWVFIGGLIQALVTALGTSSSSATLPVTFKCLEEINGVDKRVTRFVLPVGATINMDGTALYEALAAIFIAQVNNFDLNFGQIITISITATAASIGAAGIPQAGLVTMVIVLTSVGLPTDDITLIIAVDWFLDRLRTTTNVLGDSIGAGIVEHLSRHELKNRDAEMGNSVIEENEMKKPYQLISQENESEKPLDSETKM", "length": 543, "header": "tr|A0A3Q2U6I3-1|A0A3Q2U6I3_CHICK Isoform 1 of Amino acid transporter OS=Gallus gallus OX=9031 GN=SLC1A3 PE=3 SV=1 CANONICAL=A0A3Q2U6I3-1" }, "locus": { "chromosome": "Z", "start_pos": 11784243, "end_pos": 11724113, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032793.1", "url": "https://www.ensembl.org/id/ENSGALT00010032793.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019426.1", "url": "https://www.ensembl.org/id/ENSGALP00010019426.1" } ] } }, { "isoform_ac": "A0A8V0YLD1-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U6I3/entry#A0A8V0YLD1-1", "sequence": { "sequence": "MTKGNGEDPKTGSRMERFQQGVRKRTLLAKKKVQSITRDDVKSYLLRNAFVLFTVVAVILGVILGFSLRSYKMSYREVKYFSFPGELLMRMLQMLVLPLIVSSLVTGCICDVFILVII", "length": 118, "header": "tr|A0A8V0YLD1-1|A0A8V0YLD1_CHICK Computationally mapped isoform of Amino acid transporter OS=Gallus gallus OX=9031 GN=SLC1A3 PE=3 SV=1 CANONICAL=A0A3Q2U6I3-1" }, "locus": { "chromosome": "Z", "start_pos": 11744093, "end_pos": 11724113, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032762.1", "url": "https://www.ensembl.org/id/ENSGALT00010032762.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019408.1", "url": "https://www.ensembl.org/id/ENSGALP00010019408.1" } ] } }, { "isoform_ac": "A0A8V0YLD6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U6I3/entry#A0A8V0YLD6-1", "sequence": { "sequence": "MSTGSSPTEKAGVILGFSLRSYKMSYREVKYFSFPGELLMRMLQMLVLPLIVSSLVTGIAALDSKASGKMGVRAVVYYMSTTIIAVLIGIIIVVIIHPGKGTKENMHREGKIVQVTAADAFLDLIRNMFPPNLVEACFKQFKTNYEKRMFKVDIPSNDTSTVASIISNVSAAVETLTQMREEMVPVPGSVNGVNALGLVVFSISFGLVIGSMKEQGQALKDFFDSLNEAIMRLVALIMWYAPLGILFLIAGKIVEMEDMGVIGGQLAMYTVTVIIGLLIHAVIVLPLLYFLITRKNPWVFIGGLIQALVTALGTSSSSATLPVTFKCLEEINGVDKRVTRFVLPVGATINMDGTALYEALAAIFIAQVNNFDLNFGQIITISITATAASIGAAGIPQAGLVTMVIVLTSVGLPTDDITLIIAVDWFLDRLRTTTNVLGDSIGAGIVEHLSRHELKNRDAEMGNSVIEENEMKKPYQLISQENESEKPLDSETKM", "length": 494, "header": "tr|A0A8V0YLD6-1|A0A8V0YLD6_CHICK Computationally mapped isoform of Amino acid transporter OS=Gallus gallus OX=9031 GN=SLC1A3 PE=3 SV=1 CANONICAL=A0A3Q2U6I3-1" }, "locus": { "chromosome": "Z", "start_pos": 11784243, "end_pos": 11742912, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032770.1", "url": "https://www.ensembl.org/id/ENSGALT00010032770.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019413.1", "url": "https://www.ensembl.org/id/ENSGALP00010019413.1" } ] } }, { "isoform_ac": "A0A8V0YLE1-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U6I3/entry#A0A8V0YLE1-1", "sequence": { "sequence": "MTKGNGEDPKTGSRMERFQQGVRKRTLLAKKKVQSITRDDVKSYLLRNAFVLFTVVAVILGVILGFSLRSYKMSYREVKYFSFPGELLMRMLQMLVLPLIVSSLVTGIAALDSKASGKMGVRAVVYYMSTTIIAVLIGIIIVVIIHPGKGTKENMHREGKIVQVTAADAFLDLIRNMFPPNLVEACFKQFKTNYEKRMFKVDIPSNDTSTVASIISNVSAAVETLTQMREEMVPVPGSVNGVNALGLVVFSISFGLVIGSMKEQGQALKDFFDSLNEAIMRLVALIMWYAPLGILFLIAGKIVEMEDMGVIGGQLAMYTVTVIIGLLIHAVIVLPLLYFLITRKNPWVFIGGLIQALVTALGTSSSSATLPVTFKCLEEINGVDKRVTRFVLPVGATINMDGTALYEALAAIFIAQVNNFDLNFGQIITISITATAASIGAAGIPQAGLVTMVIVLTSVGLPTDDITLIIAVDWFLRHYSHICRYRGKSPRSKK", "length": 494, "header": "tr|A0A8V0YLE1-1|A0A8V0YLE1_CHICK Computationally mapped isoform of Amino acid transporter OS=Gallus gallus OX=9031 GN=SLC1A3 PE=3 SV=1 CANONICAL=A0A3Q2U6I3-1" }, "locus": { "chromosome": "Z", "start_pos": 11783561, "end_pos": 11724113, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032783.1", "url": "https://www.ensembl.org/id/ENSGALT00010032783.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019418.1", "url": "https://www.ensembl.org/id/ENSGALP00010019418.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-210455", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-210455", "resource": "Reactome", "description": "Astrocytic Glutamate-Glutamine Uptake And Metabolism" }, { "id": "R-GGA-210500", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-210500", "resource": "Reactome", "description": "Glutamate Neurotransmitter Release Cycle" }, { "id": "R-GGA-9958863", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9958863", "resource": "Reactome", "description": "SLC-mediated transport of amino acids" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8W4F8R6-1", "protein_name": "Amino acid transporter", "gene_name": "SLC1A3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MHALLAAFCCSAVPAGNSPCHCLGYLPPATKSEKLCSLTPKRKYAMTKSNGEEARMGGRMERFQQGVRKRTLLAKKKVQNITKEDVKSYLFRNAFVLLTVTAVIVGTILGFALRPYKMSYREVKYFSFPGELLMRMLQMLVLPLIISSLVTGMAALDSKASGKMGMRAVVYYMTTTVIAVVIGIIIVIIIHPGKGTKENMHREGKIVQVTAADAFLDLIRNMFPPNLVEACFKQFKTNYEKKSFKVPIQPNDTLVGAVINNVSEAMETLTRIKEELVPVPGSVNGVNALGLVVFSMCFGFVIGNMKEQGQALREFFDSLNEAIMRLVAVIMWYAPLGILFLIAGKIVEMEDMGVIGGQLAMYTVTVIVGLLIHAVIVLPLLYFLVTRKNPWVFIGGLLQALVTALGTSSSSATLPITFKCLEENNGVDKRVTRFVLPVGATINMDGTALYEALAAIFIAQVNNFELNFGQIITISITATAASIGAAGIPQAGLVTMVIVLTSVGLPTDDITLIIAVDWFLDRLRTTTNVLGDSLGAGIVEHLSRHELKNRDVEMGNSVIEENEMKKPYQLIAQESEIEKPIDSETKM", "length": 587 }, "evidence": [ { "id": "A0A3Q2U6I3", "url": "https://omabrowser.org/oma/group/A0A3Q2U6I3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P24942-1", "protein_name": "Excitatory amino acid transporter 1", "gene_name": "Slc1a3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTKSNGEEPRMGSRMERFQQGVRKRTLLAKKKVQNITKEDVKSYLFRNAFVLLTVSAVIVGTILGFALRPYKMSYREVKYFSFPGELLMRMLQMLVLPLIISSLVTGMAALDSKASGKMGMRAVVYYMTTTIIAVVIGIIIVIIIHPGKGTKENMYREGKIVQVTAADAFLDLIRNMFPPNLVEACFKQFKTSYEKRSFKVPIQANETLLGAVINNVSEAMETLTRIREEMVPVPGSVNGVNALGLVVFSMCFGFVIGNMKEQGQALREFFDSLNEAIMRLVAVIMWYAPLGILFLIAGKILEMEDMGVIGGQLAMYTVTVIVGLLIHAVIVLPLLYFLVTRKNPWVFIGGLLQALITALGTSSSSATLPITFKCLEENNGVDKRITRFVLPVGATINMDGTALYEALAAIFIAQVNNFDLNFGQIITISITATAASIGAAGIPQAGLVTMVIVLTSVGLPTDDITLIIAVDWFLDRLRTTTNVLGDSLGAGIVEHLSRHELKNRDVEMGNSVIEENEMKKPYQLIAQDNEPEKPVADSETKM", "length": 543 }, "evidence": [ { "id": "A0A3Q2U6I3", "url": "https://omabrowser.org/oma/group/A0A3Q2U6I3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P43003-1", "protein_name": "Excitatory amino acid transporter 1", "gene_name": "SLC1A3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTKSNGEEPKMGGRMERFQQGVRKRTLLAKKKVQNITKEDVKSYLFRNAFVLLTVTAVIVGTILGFTLRPYRMSYREVKYFSFPGELLMRMLQMLVLPLIISSLVTGMAALDSKASGKMGMRAVVYYMTTTIIAVVIGIIIVIIIHPGKGTKENMHREGKIVRVTAADAFLDLIRNMFPPNLVEACFKQFKTNYEKRSFKVPIQANETLVGAVINNVSEAMETLTRITEELVPVPGSVNGVNALGLVVFSMCFGFVIGNMKEQGQALREFFDSLNEAIMRLVAVIMWYAPVGILFLIAGKIVEMEDMGVIGGQLAMYTVTVIVGLLIHAVIVLPLLYFLVTRKNPWVFIGGLLQALITALGTSSSSATLPITFKCLEENNGVDKRVTRFVLPVGATINMDGTALYEALAAIFIAQVNNFELNFGQIITISITATAASIGAAGIPQAGLVTMVIVLTSVGLPTDDITLIIAVDWFLDRLRTTTNVLGDSLGAGIVEHLSRHELKNRDVEMGNSVIEENEMKKPYQLIAQDNETEKPIDSETKM", "length": 542 }, "evidence": [ { "id": "A0A3Q2U6I3", "url": "https://omabrowser.org/oma/group/A0A3Q2U6I3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P46411-1", "protein_name": "Excitatory amino acid transporter 1", "gene_name": "SLC1A3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTKSNGEEARLGGRMERFQQGVRKRTLLAKKKVQNITKEDVKSYLFRNAFVLLTVTAVIVGTILGFTLRPYRMSYREVKYFSFPGELLMRMLQMLVLPLIISSLVTGMAALDSKASGKMGMRAVVYYMTTTIIAVVIGIIIVIIIHPGKGTKENMHREGKIVQVTAADAFLDLIRNMFPPNLVEACFKQFKTNYEKRSFKVPIQPNETLVGAVINNVSEAMETLTRITEELVPVPGSVNGVNALGLVVFSMCFGFVIGNMKEQGQALREFFDSLNEAIMRLVAVIMWYAPLGILFLIAGKIVEMEDMGVIGGQLAMYTVTVIVGLLIHAVIVLPLLYFLVTRKNPWVFIGGLLQALITALGTSSSSATLPITFKCLEENNGVDKRVTRFVLPVGATINMDGTALYEALAAIFIAQVNNFELNFGQIITISITATAASIGAAGIPQAGLVTMVIVLTSVGLPTDDITLIIAVDWFLDRLRTTTNVLGDSLGAGIVEHLSRHELKNRDVEMGNSVIEENEMKKPYQLISQESEIEKSMDSETKM", "length": 542 }, "evidence": [ { "id": "A0A3Q2U6I3", "url": "https://omabrowser.org/oma/group/A0A3Q2U6I3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P56564-1", "protein_name": "Excitatory amino acid transporter 1", "gene_name": "Slc1a3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTKSNGEEPRMGGRMERLQQGVRKRTLLAKKKVQSLTKEDVKSYLFRNAFVLLTVTAVIVGTILGFALRPYKMSYREVKYFSFPGELLMRMLQMLVLPLIISSLVTGMAALDSKASGKMGMRAVVYYMTTTIIAVVIGIIIVIIIHPGKGTKENMYREGKIVQVTAADAFLDLIRNMFPPNLVEACFKQFKTSYEKRSFKVPIQSNETLLGAVINNVSEAMETLTRIREEMVPVPGSVNGVNALGLVVFSMCFGFVIGNMKEQGQALREFFDSLNEAIMRLVAVIMWYAPLGILFLIAGKIVEMEDMGVIGGQLAMYTVTVIVGLLIHAVIVLPLLYFLVTRKNPWVFIGGLLQALITALGTSSSSATLPITFKCLEENNGVDKRITRFVLPVGATINMDGTALYEALAAIFIAQVNNFDLNFGQIITISITATAASIGAAGIPQAGLVTMVIVLTSVGLPTDDITLIIAVDWFLDRLRTTTNVLGDSLGAGIVEHLSRHELKNRDVEMGNSVIEENEMKKPYQLIAQDNEPEKPVADSETKM", "length": 543 }, "evidence": [ { "id": "A0A3Q2U6I3", "url": "https://omabrowser.org/oma/group/A0A3Q2U6I3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U6I3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U6I3" } ], "pmid": "" }, { "name": "cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U6I3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U6I3" } ], "pmid": "" }, { "name": "neuronal cell body", "id": "GO:0043025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043025", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U6I3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U6I3" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U6I3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U6I3" } ], "pmid": "" }, { "name": "neuron projection", "id": "GO:0043005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043005", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U6I3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U6I3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 7, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U6I3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U6I3" } ], "pmid": "" }, { "name": "neutral L-amino acid transmembrane transporter activity", "id": "GO:0015175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015175", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U6I3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U6I3" } ], "pmid": "" }, { "name": "high-affinity L-glutamate transmembrane transporter activity", "id": "GO:0005314", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005314", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U6I3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U6I3" } ], "pmid": "" }, { "name": "glutamate:sodium symporter activity", "id": "GO:0015501", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015501", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U6I3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U6I3" } ], "pmid": "" }, { "name": "glutamate binding", "id": "GO:0016595", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016595", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U6I3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U6I3" } ], "pmid": "" }, { "name": "L-glutamate transmembrane transporter activity", "id": "GO:0005313", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005313", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U6I3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U6I3" } ], "pmid": "" }, { "name": "symporter activity", "id": "GO:0015293", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015293", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U6I3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U6I3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 8, "go_terms": [ { "name": "chloride transmembrane transport", "id": "GO:1902476", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902476", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U6I3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U6I3" } ], "pmid": "" }, { "name": "D-aspartate import across plasma membrane", "id": "GO:0070779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070779", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U6I3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U6I3" } ], "pmid": "" }, { "name": "potassium ion transmembrane transport", "id": "GO:0071805", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071805", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U6I3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U6I3" } ], "pmid": "" }, { "name": "L-glutamate import across plasma membrane", "id": "GO:0098712", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098712", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U6I3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U6I3" } ], "pmid": "" }, { "name": "L-aspartate import across plasma membrane", "id": "GO:0140009", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140009", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U6I3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U6I3" } ], "pmid": "" }, { "name": "cellular response to cocaine", "id": "GO:0071314", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071314", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U6I3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U6I3" } ], "pmid": "" }, { "name": "L-alpha-amino acid transmembrane transport", "id": "GO:1902475", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902475", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U6I3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U6I3" } ], "pmid": "" }, { "name": "L-glutamate transmembrane transport", "id": "GO:0015813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015813", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U6I3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U6I3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 206, "end_pos": 208, "annotation": "n_glycosylation_sequon" }, { "start_pos": 217, "end_pos": 219, "annotation": "n_glycosylation_sequon" }, { "start_pos": 531, "end_pos": 533, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "70699", "name": "", "equation": "K(+)(in) + L-glutamate(out) + 3 Na(+)(out) + H(+)(out) = K(+)(out) + L-glutamate(in) + 3 Na(+)(in) + H(+)(in)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "70699", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/70699" } ] }, { "id": "70851", "name": "", "equation": "K(+)(in) + L-aspartate(out) + 3 Na(+)(out) + H(+)(out) = K(+)(out) + L-aspartate(in) + 3 Na(+)(in) + H(+)(in)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "70851", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/70851" } ] }, { "id": "71379", "name": "", "equation": "D-aspartate(out) + K(+)(in) + 3 Na(+)(out) + H(+)(out) = D-aspartate(in) + K(+)(out) + 3 Na(+)(in) + H(+)(in)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "71379", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/71379" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A3Q2U6I3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 543, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A3Q2U6I3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A3Q2U6I3" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 206, "end_pos": 208 }, { "start_pos": 217, "end_pos": 219 }, { "start_pos": 531, "end_pos": 533 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], 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This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On May 17, 2018 this sequence version replaced XP_015149007.1. 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"MPSCGWFHRDLSGLEAEALLKGRGVHGSFLARPSRKNQGDFSLSVRVGDQVTHIRIQNTGDFYDLYGGEKFATLSELVEYYTQQQGSLQDKDGTIIDLRYPLNCSDPTTERWYHGHLSGVAAESLLQAKATPWTFLVRESLSKPGDFVLSVLTDQPKPGSDAPPAGATSASGARLKVTHIKIMCENGRYTVGGSEKFDSLADLVEHFKKTGIEEVSGSFVYLKQPYYATRVNAADIENRVHELNKKSLSEETSKAGFWEEFDSLQKQEAKQLFDRHEGQRPENKSKNRYKNILPFDHSRVILQGRDPNIPGSDYINANYVKNNLISPDECPKTYIASQGCLDTTVNDFWQMVWQENTHIIVMTTREVEKGRNKCVPYWPEAGSTKEYGPYLVENVGEHDALEYKLRHLCVCPINDSEAVREIWQYQYLSWPDHGVPSEPGGVLSFLDQINQKQESIPNAGPILVHCSAGIGRTGTIIVIDMIVETISTKGLDCDIDIQKTIQMVRAQRSGMVQTEAQYKFIYMAICQFIETTKRKLEVIQSQKSKQNESEYGNITYPPAVKNMHAKVSRKSSKQKETIYENLGKKEEKVRKQLSSEKKLKSSLKKK", "length": 606, "header": "tr|A0A3Q2UCN1-1|A0A3Q2UCN1_CHICK Isoform 1 of Tyrosine-protein phosphatase non-receptor type OS=Gallus gallus OX=9031 GN=PTPN6 PE=1 SV=1 CANONICAL=A0A3Q2UCN1-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2UCN1-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UCN1/entry#A0A3Q2UCN1-1", "sequence": { "sequence": "MPSCGWFHRDLSGLEAEALLKGRGVHGSFLARPSRKNQGDFSLSVRVGDQVTHIRIQNTGDFYDLYGGEKFATLSELVEYYTQQQGSLQDKDGTIIDLRYPLNCSDPTTERWYHGHLSGVAAESLLQAKATPWTFLVRESLSKPGDFVLSVLTDQPKPGSDAPPAGATSASGARLKVTHIKIMCENGRYTVGGSEKFDSLADLVEHFKKTGIEEVSGSFVYLKQPYYATRVNAADIENRVHELNKKSLSEETSKAGFWEEFDSLQKQEAKQLFDRHEGQRPENKSKNRYKNILPFDHSRVILQGRDPNIPGSDYINANYVKNNLISPDECPKTYIASQGCLDTTVNDFWQMVWQENTHIIVMTTREVEKGRNKCVPYWPEAGSTKEYGPYLVENVGEHDALEYKLRHLCVCPINDSEAVREIWQYQYLSWPDHGVPSEPGGVLSFLDQINQKQESIPNAGPILVHCSAGIGRTGTIIVIDMIVETISTKGLDCDIDIQKTIQMVRAQRSGMVQTEAQYKFIYMAICQFIETTKRKLEVIQSQKSKQNESEYGNITYPPAVKNMHAKVSRKSSKQKETIYENLGKKEEKVRKQLSSEKKLKSSLKKK", "length": 606, "header": "tr|A0A3Q2UCN1-1|A0A3Q2UCN1_CHICK Isoform 1 of Tyrosine-protein phosphatase non-receptor type OS=Gallus gallus OX=9031 GN=PTPN6 PE=1 SV=1 CANONICAL=A0A3Q2UCN1-1" }, "locus": { "chromosome": "1", "start_pos": 77296994, "end_pos": 77277638, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010057197.1", "url": "https://www.ensembl.org/id/ENSGALT00010057197.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034788.1", "url": "https://www.ensembl.org/id/ENSGALP00010034788.1" } ] } }, { "isoform_ac": "F1N843-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UCN1/entry#F1N843-1", "sequence": { "sequence": "MVRWFHRDLSGLEAEALLKGRGVHGSFLARPSRKNQGDFSLSVRVGDQVTHIRIQNTGDFYDLYGGEKFATLSELVEYYTQQQGSLQDKDGTIIDLRYPLNCSDPTTERWYHGHLSGVAAESLLQAKATPWTFLVRESLSKPGDFVLSVLTDQPKPGSDAPPAGATSASGARLKVTHIKIMCENGRYTVGGSEKFDSLADLVEHFKKTGIEEVSGSFVYLKQPYYATRVNAADIENRVHELNKKSLSEETSKAGFWEEFDSLQKQEAKQLFDRHEGQRPENKSKNRYKNILPFDHSRVILQGRDPNIPGSDYINANYVKNNLISPDECPKTYIASQGCLDTTVNDFWQMVWQENTHIIVMTTREVEKGRNKCVPYWPEAGSTKEYGPYLVENVGEHDALEYKLRHLCVCPINDSEAVREIWQYQYLSWPDHGVPSEPGGVLSFLDQINQKQESIPNAGPILVHCSAGIGRTGTIIVIDMIVETISTKGLDCDIDIQKTIQMVRAQRSGMVQTEAQYKFIYMAICQFIETTKRKLEVIQSQKSKQNESEYGNITYPPAVKNMHAKVSRKSSKQKETIYENLGKKEEKVRKQLSSEKKLKSSLKKK", "length": 604, "header": "tr|F1N843-1|A0A3Q2UCN1_CHICK Computationally mapped isoform of Tyrosine-protein phosphatase non-receptor type OS=Gallus gallus OX=9031 GN=PTPN6 PE=1 SV=3 CANONICAL=A0A3Q2UCN1-1" }, "locus": { "chromosome": "1", "start_pos": 77296994, "end_pos": 77288441, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010057186.1", "url": "https://www.ensembl.org/id/ENSGALT00010057186.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034779.1", "url": "https://www.ensembl.org/id/ENSGALP00010034779.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:427947", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427947", "resource": "KEGG Pathway" }, { "id": "R-GGA-1433559", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1433559", "resource": "Reactome", "description": "Regulation of KIT signaling" }, { "id": "R-GGA-201556", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-201556", "resource": "Reactome", "description": "Signaling by ALK" }, { "id": "R-GGA-210990", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-210990", "resource": "Reactome", "description": "PECAM1 interactions" }, { "id": "R-GGA-389948", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-389948", "resource": "Reactome", "description": "Co-inhibition by PD-1" }, { "id": "R-GGA-432142", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-432142", "resource": "Reactome", "description": "Platelet sensitization by LDL" }, { "id": "R-GGA-512988", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-512988", "resource": "Reactome", "description": "Interleukin-3, Interleukin-5 and GM-CSF signaling" }, { "id": "R-GGA-6798695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798695", "resource": "Reactome", "description": "Neutrophil degranulation" }, { "id": "R-GGA-877300", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-877300", "resource": "Reactome", "description": "Interferon gamma signaling" }, { "id": "R-GGA-912526", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-912526", "resource": "Reactome", "description": "Interleukin receptor SHC signaling" }, { "id": "R-GGA-912694", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-912694", "resource": "Reactome", "description": "Regulation of IFNA/IFNB signaling" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A2R8Q2T0-1", "protein_name": "Tyrosine-protein phosphatase non-receptor type", "gene_name": "ptpn6", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MFNRWFHRDLSGLDAEAVLKSRGVHGSFLARPSKKNVGDFSLSVRVGEIITHIRIQNTGDYYDLYGGEKFATLAELVEYYTGDHGTLQDKDGTVIELKYPLNCSDPTTERWYHGHLSGPNAEKLLRERNEPGTFLVRESLSKPGDFVLSALTDDQTSSGRRVSHIKIMCNNDRYTVGGKDQFDNLTDLVEHFKRVGIEELSGTMVYLKQPYYSTRLNAADIQSRVNQLDQTSEREKMDGADKKIKAGFWEEFDALQKLETKVTKSRDEGMRPENKSKNRYKNILPFDETRVILENADPNVVGSDYINANYVINKLMVTNPQKTYIACQGCLATTVDDFWQMMWQEDSRVIVMTTREVEKGRNKCVPYWPTTEGESKEVGRYVVKLLSEMDAADYKVRVVELSAPHRNEAPRKIWHFQYLSWPDHGVPQEPGGVLSFLDQVNRKQEELRSSAPIVIHCSAGIGRTGTIVVIDMLIDSIDAKGLDCDIDIQKCIMMVRDQRSGMVQTEAQYKFIYLAVLQYIESTKVTRRAIMETETEYGNLSIQSKHPKASRKASSKKNEDVYENLGAKGKKDVKKQKSEEKKGGGSVRKR", "length": 590 }, "evidence": [ { "id": "A0A3Q2UCN1", "url": "https://omabrowser.org/oma/group/A0A3Q2UCN1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A4X1UZH9-1", "protein_name": "Tyrosine-protein phosphatase non-receptor type", "gene_name": "PTPN6", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLSRGWFHRDLSGLDAETLLKGRGVHGSFLARPSRKNQGDFSLSVRVGDQVTHIRIQNSGDFYDLYGGEKFATLTELVEYYTQQQGVLQDRDGTIIHLKYPLNCSDPTSERWYHGHMSGGQAETLLQAKGEPWTFLVRESLSQPGDFVLSVLSDQPKAGPGSPLKVTHIKVMCEGGRYTVGGPETFDSLTDLVEHFKKTGIEEASGAFVYLRQPYYATRVNAADIENRVLELNKKQESEETAKAGFWEEFESLQKQEVKNLHQRLEGQRPENKSKNRYKNILPFDHSRVILQGRDSNIPGSDYINANYVKNKLLGPDENAKTYIASQGCLEATVNDFWQMVWQENTRVIVMTTREVEKGRNKCVPYWPEVGSQRVYGPYAVTNGGEHDTAEYKLRTLQVSPLANGDLVREIWHYQYLSWPDHGVPSEPGGVLSFLDQINQRQESLPHAGPIIVHCSAGIGRTGTIIVIDMLMESISTKGLDCDIDIQKTIQMVRAQRSGMVQTEAQYKFIYVAIAQFIETTKKKLEVIQSQKGRESEYGNITYPLAMKNAHAKASRTSSKHKEDVYENVHSKNKKEEKVKKQRSADKEKSKGSLKRK", "length": 597 }, "evidence": [ { "id": "A0A3Q2UCN1", "url": "https://omabrowser.org/oma/group/A0A3Q2UCN1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P29350-1", "protein_name": "Tyrosine-protein phosphatase non-receptor type 6", "gene_name": "PTPN6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVRWFHRDLSGLDAETLLKGRGVHGSFLARPSRKNQGDFSLSVRVGDQVTHIRIQNSGDFYDLYGGEKFATLTELVEYYTQQQGVLQDRDGTIIHLKYPLNCSDPTSERWYHGHMSGGQAETLLQAKGEPWTFLVRESLSQPGDFVLSVLSDQPKAGPGSPLRVTHIKVMCEGGRYTVGGLETFDSLTDLVEHFKKTGIEEASGAFVYLRQPYYATRVNAADIENRVLELNKKQESEDTAKAGFWEEFESLQKQEVKNLHQRLEGQRPENKGKNRYKNILPFDHSRVILQGRDSNIPGSDYINANYIKNQLLGPDENAKTYIASQGCLEATVNDFWQMAWQENSRVIVMTTREVEKGRNKCVPYWPEVGMQRAYGPYSVTNCGEHDTTEYKLRTLQVSPLDNGDLIREIWHYQYLSWPDHGVPSEPGGVLSFLDQINQRQESLPHAGPIIVHCSAGIGRTGTIIVIDMLMENISTKGLDCDIDIQKTIQMVRAQRSGMVQTEAQYKFIYVAIAQFIETTKKKLEVLQSQKGQESEYGNITYPPAMKNAHAKASRTSSKHKEDVYENLHTKNKREEKVKKQRSADKEKSKGSLKRK", "length": 595 }, "evidence": [ { "id": "A0A3Q2UCN1", "url": "https://omabrowser.org/oma/group/A0A3Q2UCN1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P29351-1", "protein_name": "Tyrosine-protein phosphatase non-receptor type 6", "gene_name": "Ptpn6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVRWFHRDLSGPDAETLLKGRGVPGSFLARPSRKNQGDFSLSVRVDDQVTHIRIQNSGDFYDLYGGEKFATLTELVEYYTQQQGILQDRDGTIIHLKYPLNCSDPTSERWYHGHISGGQAESLLQAKGEPWTFLVRESLSQPGDFVLSVLNDQPKAGPGSPLRVTHIKVMCEGGRYTVGGSETFDSLTDLVEHFKKTGIEEASGAFVYLRQPYYATRVNAADIENRVLELNKKQESEDTAKAGFWEEFESLQKQEVKNLHQRLEGQRPENKSKNRYKNILPFDHSRVILQGRDSNIPGSDYINANYVKNQLLGPDENSKTYIASQGCLDATVNDFWQMAWQENTRVIVMTTREVEKGRNKCVPYWPEVGTQRVYGLYSVTNSREHDTAEYKLRTLQISPLDNGDLVREIWHYQYLSWPDHGVPSEPGGVLSFLDQINQRQESLPHAGPIIVHCSAGIGRTGTIIVIDMLMESISTKGLDCDIDIQKTIQMVRAQRSGMVQTEAQYKFIYVAIAQFIETTKKKLEIIQSQKGQESEYGNITYPPAVRSAHAKASRTSSKHKEEVYENVHSKSKKEEKVKKQRSADKEKNKGSLKRK", "length": 595 }, "evidence": [ { "id": "A0A3Q2UCN1", "url": "https://omabrowser.org/oma/group/A0A3Q2UCN1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P81718-1", "protein_name": "Tyrosine-protein phosphatase non-receptor type 6", "gene_name": "Ptpn6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLSRGWFHRDLSGPDAETLLKGRGVPGSFLARPSRKNQGDFSLSVRVDDQVTHIRIQNSGDFYDLYGGEKFATSTELVEYYTQQQGILQDRDGTIIHLKYPLNCSDPTSERWYHGHMSGGQAESLLQAKGEPWTFLVRESLSQPGDFVLSVLNDQPKAAPGSPLRVTHIKVMCEGGRYTVGGSETFDSLTDLVEHFKKTGIEEASGAFVYLRQPYYATRVNAADIENRVLELNKKQESEDTAKAGFWEEFESLQKQEAKNLHQRLEGQRPENKSKNRYKNILPFDHSRVILQGRDSNIPGSDYINANYVKNQLLGPDENSKTYIASQGCLDATVNDFWQMAWQENTRVIVMTTREVEKGRNKCVPYWPEVGTQRVYGLYSVTNCKEHDTAEYKLRTLQISPLDNGDLVREIWHYQYLSWPDHGVPSEPGGVLSFLDQINQRQESLPHAGPIIVHCSAGIGRTGTIIVIDMLMESVSTKGLDCDIDIQKTIQMVRAQRSGMVQTEAQYKFIYVAIAQFIETTKKKLEIIQSQRGQESEYGNITYPPALRSAHAKASRTSSKHKEEVYENVHSKNKKEEKVKKQRSADKEKNKGSLKRNISLTPCRGLRWADRDL", "length": 613 }, "evidence": [ { "id": "A0A3Q2UCN1", "url": "https://omabrowser.org/oma/group/A0A3Q2UCN1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 18, "go_terms": [ { "name": "mitotic cell cycle", "id": "GO:0000278", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000278", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UCN1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UCN1" } ], "pmid": "" }, { "name": "positive regulation of cell population proliferation", "id": "GO:0008284", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008284", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UCN1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UCN1" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UCN1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UCN1" } ], "pmid": "" }, { "name": "positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction", "id": "GO:0051897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051897", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UCN1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UCN1" } ], "pmid": "" }, { "name": "negative regulation of interleukin-6 production", "id": "GO:0032715", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032715", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UCN1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UCN1" } ], "pmid": "" }, { "name": "negative regulation of tumor necrosis factor production", "id": "GO:0032720", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032720", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UCN1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UCN1" } ], "pmid": "" }, { "name": "T cell activation", "id": "GO:0042110", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042110", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UCN1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UCN1" } ], "pmid": "" }, { "name": "negative regulation of angiogenesis", "id": "GO:0016525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016525", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UCN1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UCN1" } ], "pmid": "" }, { "name": "regulation of ERK1 and ERK2 cascade", "id": "GO:0070372", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070372", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UCN1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UCN1" } ], "pmid": "" }, { "name": "regulation of G1/S transition of mitotic cell cycle", "id": "GO:2000045", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000045", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UCN1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UCN1" } ], "pmid": "" }, { "name": "negative regulation of innate immune response", "id": "GO:0045824", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045824", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UCN1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UCN1" } ], "pmid": "" }, { "name": "negative regulation of lipopolysaccharide-mediated signaling pathway", "id": "GO:0031665", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031665", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UCN1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UCN1" } ], "pmid": "" }, { "name": "negative regulation of mast cell activation involved in immune response", "id": "GO:0033007", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033007", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UCN1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UCN1" } ], "pmid": "" }, { "name": "negative regulation of B cell receptor signaling pathway", "id": "GO:0050859", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050859", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UCN1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UCN1" } ], "pmid": "" }, { "name": "negative regulation of neutrophil activation", "id": "GO:1902564", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902564", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UCN1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UCN1" } ], "pmid": "" }, { "name": "epididymis development", "id": "GO:1905867", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905867", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UCN1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UCN1" } ], "pmid": "" }, { "name": "negative regulation of inflammatory response to wounding", "id": "GO:0106015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106015", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UCN1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UCN1" } ], "pmid": "" }, { "name": "CD27 signaling pathway", "id": "GO:0160162", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160162", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UCN1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UCN1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 9, "go_terms": [ { "name": "phosphotyrosine residue binding", "id": "GO:0001784", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001784", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UCN1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UCN1" } ], "pmid": "" }, { "name": "SH3 domain binding", "id": "GO:0017124", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017124", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UCN1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UCN1" } ], "pmid": "" }, { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UCN1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UCN1" } ], "pmid": "" }, { "name": "cell adhesion molecule binding", "id": "GO:0050839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050839", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UCN1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UCN1" } ], "pmid": "" }, { "name": "SH2 domain binding", "id": "GO:0042169", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042169", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UCN1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UCN1" } ], "pmid": "" }, { "name": "transmembrane receptor protein tyrosine phosphatase activity", "id": "GO:0005001", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005001", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UCN1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UCN1" } ], "pmid": "" }, { "name": "non-membrane spanning protein tyrosine phosphatase activity", "id": "GO:0004726", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004726", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UCN1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UCN1" } ], "pmid": "" }, { "name": "phosphorylation-dependent protein binding", "id": "GO:0140031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140031", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UCN1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UCN1" } ], "pmid": "" }, { "name": "protein tyrosine phosphatase activity", "id": "GO:0004725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004725", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UCN1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UCN1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UCN1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UCN1" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UCN1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UCN1" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UCN1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UCN1" } ], "pmid": "" }, { "name": "cell-cell junction", "id": "GO:0005911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005911", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UCN1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UCN1" } ], "pmid": "" }, { "name": "alpha-beta T cell receptor complex", "id": "GO:0042105", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042105", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UCN1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UCN1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 103, "end_pos": 105, "annotation": "n_glycosylation_sequon" }, { "start_pos": 283, "end_pos": 285, "annotation": "n_glycosylation_sequon" }, { "start_pos": 414, "end_pos": 416, "annotation": "n_glycosylation_sequon" }, { "start_pos": 547, "end_pos": 549, "annotation": "n_glycosylation_sequon" }, { "start_pos": 553, "end_pos": 555, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "10684", "name": "", "equation": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A1D5PI23-1", "F1P225-1", "A0A8V0XA98-1", "A0A8V0X472-1", "A0A8V0XI03-1", "A0A1D5P5S2-1", "A0A1D5PC43-1", "P0C597-1", "Q5F4B1-1", "Q6YI48-1", "Q90687-1", "Q98936-1", "Q9PW71-1", "A0A8V0YWD3-1", "A0A8V0Y719-1", "A0A8V0Z2T2-1", "A0A8V0Z920-1", "A0A8V0ZLS3-1", "A0A8V0YHN7-1", "A0A8V0X4H3-1", "Q5ZKG5-1", "Q9YH99-1", "Q9YHA0-1", "F1NCC5-1", "F1NAX3-1", "A0A8V0X8Q6-1", "A0A3Q2TZZ7-1", "A0A1D5NXI7-1", "A0A8V0YAF3-1", "A0A8V0XYX4-1", "A0A8V0YFZ7-1", "A0A8V0XVI4-1", "A0A8V0YFC8-1", "A0A8V0YAP9-1", "A0A8V0YVP7-1", "A0A8V0YIN5-1", "A0A8V0ZMU4-1", "A0A8V0ZPJ8-1", "F1NVR5-1", "A0A8V0ZVG8-1", "A0A8V0ZH43-1", "A0A8V0ZVC2-1", "A0A8V0ZQ53-1", "A0A1D5P6Q1-1", "Q9YH98-1", "A0A8V1A896-1", "A0A8V1AB05-1", "A0A3Q2UCN1-1", "A0A8V1A4B8-1", "A0A8V0ZJ28-1", "F1NWE3-1", "O13016-1", "Q9W6V5-1", "E1BRQ8-1", "A0A1D5P6X3-1", "A0A8V0XAP8-1", "A0A1D5PMZ4-1", "F1N842-1", "A0A8V0YC26-1", "A0A8V0ZXB3-1" ], "evidence": [ { "id": "10684", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/10684" } ] }, { "id": "R-GGA-205306", "name": "Interaction of SHP1 and KIT", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q2UCN1-1", "Q08156-1" ], "evidence": [ { "id": "R-GGA-205306", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-205306" } ] }, { "id": "R-GGA-210277", "name": "Interaction of PECAM-1 and SHP-1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q2UCN1-1" ], "evidence": [ { "id": "R-GGA-210277", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-210277" } ] }, { "id": "R-GGA-389759", "name": "Interaction of SHP-1 or SHP-2 with phospho PD-1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q90687-1", "A0A8V0ZND5-1", "A0A8V0Z0R8-1", "A0A3Q2UCN1-1" ], "evidence": [ { "id": "R-GGA-389759", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-389759" } ] }, { "id": "R-GGA-6798745", "name": "Exocytosis of tertiary granule lumen proteins", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "extracellular region, tertiary granule lumen", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0X7U8-1", "A0A8V0X868-1", "A0A8V0XIL3-1", "A0A8V1AIR0-1", "A2JDL7-1", "P08267-1", "A0A1D5PN36-1", "Q90629-1", "R4GH41-1", "A0A8V0Y6Q3-1", "A0A8V1AMW1-1", "A0A8V0ZN26-1", "A0A8V0ZPK4-1", "F1NN63-1", "A0A8V0YXL9-1", "A0A8V0ZNL2-1", "E1C9D9-1", "A0A8V0ZG12-1", "A0A3Q2UCN1-1", "P00698-1", "Q05744-1", "A0A8V0XX04-1", "A0A8V0Y248-1" ], "evidence": [ { "id": "R-GGA-6798745", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798745" } ] }, { "id": "R-GGA-6798749", "name": "Exocytosis of specific granule lumen proteins", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "extracellular region, specific granule lumen", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0X868-1", "A0A8V0XAC6-1", "A0A8V0XIL3-1", "A0A8V1AD74-1", "A0A8V1AMW1-1", "A0A8V0ZNL2-1", "Q8QFM7-1", "E1C9D9-1", "A0A8V0YW12-1", "A0A8V0ZJW2-1", "A0A3Q2UCN1-1", "P00698-1", "Q05744-1", "A0A8V0XX04-1", "A0A8V0Y248-1", "A0A8V0YBU4-1" ], "evidence": [ { "id": "R-GGA-6798749", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798749" } ] }, { "id": "R-GGA-873918", "name": "Transphosphorylation of JAK1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZSN8-1", "A0A8V0YNY4-1", "A0A3Q2UCN1-1" ], "evidence": [ { "id": "R-GGA-873918", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-873918" } ] }, { "id": "R-GGA-909738", "name": "SHP1 and SHP2 bind the common beta chain", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q90687-1", "A0A8V0YNY4-1", "A0A3Q2UCN1-1" ], "evidence": [ { "id": "R-GGA-909738", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-909738" } ] }, { "id": "R-GGA-913424", "name": "The SHC1:SHIP1 complex is stabilized by GRB2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YNY4-1", "A0A3Q2UCN1-1" ], "evidence": [ { "id": "R-GGA-913424", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-913424" } ] }, { "id": "R-GGA-914036", "name": "SHP1 and SHP2 dephosphorylate Y628 of IL3RB", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q90687-1", "A0A8V0YNY4-1", "A0A3Q2UCN1-1" ], "evidence": [ { "id": "R-GGA-914036", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-914036" } ] }, { "id": "R-GGA-9701507", "name": "PTPN6 dephosphorylates JAK3", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V1A9R2-1", "A0A8V0Z3S3-1", "A0A3Q2UCN1-1" ], "evidence": [ { "id": "R-GGA-9701507", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9701507" } ] }, { "id": "R-GGA-997314", "name": "Dephosphorylation of JAK1 by SHP1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0X5W9-1", "A0A8V0ZSN8-1", "A0A3Q2UCN1-1" ], "evidence": [ { "id": "R-GGA-997314", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-997314" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5NXI7", "gene_name": "EYA4", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A1D5NXI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NXI7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A1D5NXI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NXI7" } ] } ] }, { "uniprot_ac": "A0A1D5P5S2", "gene_name": "DUSP5", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A1D5P5S2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P5S2" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A1D5P5S2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P5S2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A1D5P5S2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P5S2" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A1D5P5S2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P5S2" } ] } ] }, { "uniprot_ac": "A0A1D5P6Q1", "gene_name": "PTPN21", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A1D5P6Q1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P6Q1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A1D5P6Q1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P6Q1" } ] } ] }, { "uniprot_ac": "A0A1D5P6X3", "gene_name": "UBASH3B", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A1D5P6X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P6X3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A1D5P6X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P6X3" } ] } ] }, { "uniprot_ac": "A0A1D5PC43", "gene_name": "EYA2", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A1D5PC43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PC43" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A1D5PC43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PC43" } ] } ] }, { "uniprot_ac": "A0A1D5PI23", "gene_name": "DUSP3", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A1D5PI23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PI23" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A1D5PI23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PI23" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A1D5PI23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PI23" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A1D5PI23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PI23" } ] } ] }, { "uniprot_ac": "A0A1D5PMZ4", "gene_name": "PTP4A3", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A1D5PMZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMZ4" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A1D5PMZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMZ4" } ] } ] }, { "uniprot_ac": "A0A1D5PN36", "gene_name": "LOC107054567", "activity": [ { "ec_number": "3.4.21.4", "activity": "Preferential cleavage: Arg-|-Xaa, Lys-|-Xaa.", "evidence": [ { "id": "A0A1D5PN36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PN36" } ] }, { "ec_number": "3.4.21.4", "activity": "", "evidence": [ { "id": "A0A1D5PN36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PN36" } ] } ] }, { "uniprot_ac": "A0A3Q2TZZ7", "gene_name": "PTPRF", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q2TZZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TZZ7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3Q2TZZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TZZ7" } ] } ] }, { "uniprot_ac": "A0A3Q2UCN1", "gene_name": "PTPN6", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q2UCN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UCN1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3Q2UCN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UCN1" } ] } ] }, { "uniprot_ac": "A0A8V0X472", "gene_name": "PTPRM", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0X472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X472" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0X472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X472" } ] } ] }, { "uniprot_ac": "A0A8V0X4H3", "gene_name": "PTPN2", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0X4H3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X4H3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0X4H3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X4H3" } ] } ] }, { "uniprot_ac": "A0A8V0X5W9", "gene_name": "TYK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X5W9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X5W9" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0X5W9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X5W9" } ] } ] }, { "uniprot_ac": "A0A8V0X7U8", "gene_name": "ALDOA", "activity": [ { "ec_number": "4.1.2.13", "activity": "beta-D-fructose 1,6-bisphosphate = D-glyceraldehyde 3-phosphate + dihydroxyacetone phosphate.", "evidence": [ { "id": "A0A8V0X7U8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X7U8" } ] }, { "ec_number": "4.1.2.13", "activity": "", "evidence": [ { "id": "A0A8V0X7U8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X7U8" } ] } ] }, { "uniprot_ac": "A0A8V0X868", "gene_name": "GGH", "activity": [ { "ec_number": "3.4.19.9", "activity": "(6S)-5,6,7,8-tetrahydrofolyl-(gamma-L-Glu)(n) + (n-1) H2O = (6S)-5,6,7,8-tetrahydrofolate + (n-1) L-glutamate.", "evidence": [ { "id": "A0A8V0X868", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X868" } ] }, { "ec_number": "3.4.19.9", "activity": "", "evidence": [ { "id": "A0A8V0X868", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X868" } ] } ] }, { "uniprot_ac": "A0A8V0X8Q6", "gene_name": "EYA1", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0X8Q6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X8Q6" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0X8Q6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X8Q6" } ] } ] }, { "uniprot_ac": "A0A8V0XA98", "gene_name": "PTPRZ1", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0XA98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XA98" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0XA98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XA98" } ] } ] }, { "uniprot_ac": "A0A8V0XAC6", "gene_name": "HPSE", "activity": [ { "ec_number": "3.2.1.166", "activity": "endohydrolysis of (1->4)-beta-D-glycosidic bonds of heparan sulfate chains in heparan sulfate proteoglycan.", "evidence": [ { "id": "A0A8V0XAC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XAC6" } ] }, { "ec_number": "3.2.1.166", "activity": "", "evidence": [ { "id": "A0A8V0XAC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XAC6" } ] } ] }, { "uniprot_ac": "A0A8V0XAP8", "gene_name": "PTPN13", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0XAP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XAP8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0XAP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XAP8" } ] } ] }, { "uniprot_ac": "A0A8V0XI03", "gene_name": "PTPRK", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0XI03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XI03" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0XI03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XI03" } ] } ] }, { "uniprot_ac": "A0A8V0XIL3", "gene_name": "NIT2", "activity": [ { "ec_number": "3.5.1.3", "activity": "2-oxosuccinamate + H2O = oxaloacetate + NH4(+).", "evidence": [ { "id": "A0A8V0XIL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XIL3" } ] }, { "ec_number": "3.5.1.3", "activity": "", "evidence": [ { "id": "A0A8V0XIL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XIL3" } ] } ] }, { "uniprot_ac": "A0A8V0XVI4", "gene_name": "LOC100858919", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0XVI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XVI4" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0XVI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XVI4" } ] } ] }, { "uniprot_ac": "A0A8V0XX04", "gene_name": "QPCT", "activity": [ { "ec_number": "2.3.2.5", "activity": "N-terminal L-glutaminyl-[peptide] = N-terminal 5-oxo-L-prolyl-[peptide] + NH4(+).", "evidence": [ { "id": "A0A8V0XX04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XX04" } ] }, { "ec_number": "2.3.2.5", "activity": "", "evidence": [ { "id": "A0A8V0XX04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XX04" } ] } ] }, { "uniprot_ac": "A0A8V0XYX4", "gene_name": "DUSP1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0XYX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XYX4" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0XYX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XYX4" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0XYX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XYX4" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0XYX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XYX4" } ] } ] }, { "uniprot_ac": "A0A8V0Y248", "gene_name": "QSOX1", "activity": [ { "ec_number": "1.8.3.2", "activity": "2 R'C(R)SH + O2 = R'C(R)S-S(R)CR' + H2O2.", "evidence": [ { "id": "A0A8V0Y248", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y248" } ] }, { "ec_number": "1.8.3.2", "activity": "", "evidence": [ { "id": "A0A8V0Y248", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y248" } ] } ] }, { "uniprot_ac": "A0A8V0Y6Q3", "gene_name": "LTA4H", "activity": [ { "ec_number": "3.3.2.6", "activity": "leukotriene A4 + H2O = leukotriene B4.", "evidence": [ { "id": "A0A8V0Y6Q3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6Q3" } ] }, { "ec_number": "3.3.2.6", "activity": "", "evidence": [ { "id": "A0A8V0Y6Q3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6Q3" } ] } ] }, { "uniprot_ac": "A0A8V0Y719", "gene_name": "PTPN3", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0Y719", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y719" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0Y719", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y719" } ] } ] }, { "uniprot_ac": "A0A8V0YAF3", "gene_name": "PTPN12", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0YAF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAF3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0YAF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAF3" } ] } ] }, { "uniprot_ac": "A0A8V0YAP9", "gene_name": "EYA3", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0YAP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAP9" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0YAP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAP9" } ] } ] }, { "uniprot_ac": "A0A8V0YBU4", "gene_name": "PDXK", "activity": [ { "ec_number": "2.7.1.35", "activity": "pyridoxine + ATP = pyridoxine 5'-phosphate + ADP + H(+).", "evidence": [ { "id": "A0A8V0YBU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBU4" } ] }, { "ec_number": "2.7.1.35", "activity": "", "evidence": [ { "id": "A0A8V0YBU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBU4" } ] } ] }, { "uniprot_ac": "A0A8V0YC26", "gene_name": "DUSP19", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0YC26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC26" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0YC26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC26" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0YC26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC26" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0YC26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC26" } ] } ] }, { "uniprot_ac": "A0A8V0YFC8", "gene_name": "PTPRC", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0YFC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFC8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0YFC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFC8" } ] } ] }, { "uniprot_ac": "A0A8V0YFZ7", "gene_name": "PTPRD", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0YFZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFZ7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0YFZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFZ7" } ] } ] }, { "uniprot_ac": "A0A8V0YHN7", "gene_name": "PTPN1", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0YHN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0YHN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN7" } ] } ] }, { "uniprot_ac": "A0A8V0YIN5", "gene_name": "PTPRB", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0YIN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIN5" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0YIN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIN5" } ] } ] }, { "uniprot_ac": "A0A8V0YNY4", "gene_name": "JAK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YNY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNY4" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0YNY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNY4" } ] } ] }, { "uniprot_ac": "A0A8V0YVP7", "gene_name": "PTPRU", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0YVP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVP7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0YVP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVP7" } ] } ] }, { "uniprot_ac": "A0A8V0YW12", "gene_name": "FRK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YW12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YW12" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0YW12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YW12" } ] } ] }, { "uniprot_ac": "A0A8V0YWD3", "gene_name": "PTPRA", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0YWD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YWD3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0YWD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YWD3" } ] } ] }, { "uniprot_ac": "A0A8V0YXL9", "gene_name": "MMP9", "activity": [ { "ec_number": "3.4.24.35", "activity": "Cleavage of gelatin types I and V and collagen types IV and V.", "evidence": [ { "id": "A0A8V0YXL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXL9" } ] }, { "ec_number": "3.4.24.35", "activity": "", "evidence": [ { "id": "A0A8V0YXL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXL9" } ] } ] }, { "uniprot_ac": "A0A8V0Z0R8", "gene_name": "LCK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z0R8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0R8" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0Z0R8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0R8" } ] } ] }, { "uniprot_ac": "A0A8V0Z2T2", "gene_name": "DUSP26", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0Z2T2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2T2" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0Z2T2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2T2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0Z2T2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2T2" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0Z2T2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2T2" } ] } ] }, { "uniprot_ac": "A0A8V0Z3S3", "gene_name": "ALK", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z3S3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3S3" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0Z3S3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3S3" } ] } ] }, { "uniprot_ac": "A0A8V0Z920", "gene_name": "PTPN4", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0Z920", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z920" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0Z920", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z920" } ] } ] }, { "uniprot_ac": "A0A8V0ZG12", "gene_name": "CDA", "activity": [ { "ec_number": "3.5.4.5", "activity": "cytidine + H2O + H(+) = uridine + NH4(+).", "evidence": [ { "id": "A0A8V0ZG12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG12" } ] }, { "ec_number": "3.5.4.5", "activity": "", "evidence": [ { "id": "A0A8V0ZG12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG12" } ] } ] }, { "uniprot_ac": "A0A8V0ZH43", "gene_name": "PTPRG", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZH43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH43" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0ZH43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH43" } ] } ] }, { "uniprot_ac": "A0A8V0ZJ28", "gene_name": "PTEN", "activity": [ { "ec_number": "3.1.3.67", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + phosphate.", "evidence": [ { "id": "A0A8V0ZJ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ28" } ] }, { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZJ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ28" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZJ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ28" } ] }, { "ec_number": "3.1.3.67", "activity": "", "evidence": [ { "id": "A0A8V0ZJ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ28" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0ZJ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ28" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZJ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ28" } ] } ] }, { "uniprot_ac": "A0A8V0ZJW2", "gene_name": "RAB27A", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZJW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJW2" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0ZJW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJW2" } ] } ] }, { "uniprot_ac": "A0A8V0ZLS3", "gene_name": "LOC419429", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZLS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLS3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0ZLS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLS3" } ] } ] }, { "uniprot_ac": "A0A8V0ZMU4", "gene_name": "DUSP13", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZMU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMU4" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZMU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMU4" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZMU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMU4" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0ZMU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMU4" } ] } ] }, { "uniprot_ac": "A0A8V0ZN26", "gene_name": "LOC121106429", "activity": [ { "ec_number": "3.4.21.4", "activity": "Preferential cleavage: Arg-|-Xaa, Lys-|-Xaa.", "evidence": [ { "id": "A0A8V0ZN26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN26" } ] }, { "ec_number": "3.4.21.4", "activity": "", "evidence": [ { "id": "A0A8V0ZN26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN26" } ] } ] }, { "uniprot_ac": "A0A8V0ZND5", "gene_name": "CSK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZND5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZND5" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0ZND5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZND5" } ] } ] }, { "uniprot_ac": "A0A8V0ZNL2", "gene_name": "C1R", "activity": [ { "ec_number": "3.4.21.41", "activity": "Selective cleavage of Lys(or Arg)-|-Ile bond in complement subcomponent C1s to form the active form of C1s (EC 3.4.21.42).", "evidence": [ { "id": "A0A8V0ZNL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNL2" } ] }, { "ec_number": "3.4.21.41", "activity": "", "evidence": [ { "id": "A0A8V0ZNL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNL2" } ] } ] }, { "uniprot_ac": "A0A8V0ZPJ8", "gene_name": "LOC100857573", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZPJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPJ8" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZPJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPJ8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0ZPJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPJ8" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZPJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPJ8" } ] } ] }, { "uniprot_ac": "A0A8V0ZPK4", "gene_name": "IDH1", "activity": [ { "ec_number": "1.1.1.42", "activity": "D-threo-isocitrate + NADP(+) = 2-oxoglutarate + CO2 + NADPH.", "evidence": [ { "id": "A0A8V0ZPK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPK4" } ] }, { "ec_number": "1.1.1.42", "activity": "", "evidence": [ { "id": "A0A8V0ZPK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPK4" } ] } ] }, { "uniprot_ac": "A0A8V0ZQ53", "gene_name": "DUSP29", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZQ53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ53" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZQ53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ53" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZQ53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ53" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0ZQ53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ53" } ] } ] }, { "uniprot_ac": "A0A8V0ZSN8", "gene_name": "JAK1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZSN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSN8" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0ZSN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSN8" } ] } ] }, { "uniprot_ac": "A0A8V0ZVC2", "gene_name": "PTPRJ", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZVC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVC2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0ZVC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVC2" } ] } ] }, { "uniprot_ac": "A0A8V0ZVG8", "gene_name": "PTPRT", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZVG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVG8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0ZVG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVG8" } ] } ] }, { "uniprot_ac": "A0A8V0ZXB3", "gene_name": "DUSP28", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZXB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXB3" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZXB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXB3" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZXB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXB3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0ZXB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXB3" } ] } ] }, { "uniprot_ac": "A0A8V1A4B8", "gene_name": "PTPRVP", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V1A4B8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4B8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V1A4B8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4B8" } ] } ] }, { "uniprot_ac": "A0A8V1A896", "gene_name": "CDC25A", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V1A896", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A896" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V1A896", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A896" } ] } ] }, { "uniprot_ac": "A0A8V1A9R2", "gene_name": "JAK3", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A9R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9R2" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V1A9R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9R2" } ] } ] }, { "uniprot_ac": "A0A8V1AB05", "gene_name": "PTPRS", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V1AB05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB05" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V1AB05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB05" } ] } ] }, { "uniprot_ac": "A0A8V1AD74", "gene_name": "AOC1", "activity": [ { "ec_number": "1.4.3.-", "activity": "", "evidence": [ { "id": "A0A8V1AD74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD74" } ] } ] }, { "uniprot_ac": "A0A8V1AIR0", "gene_name": "ALDOC", "activity": [ { "ec_number": "4.1.2.13", "activity": "beta-D-fructose 1,6-bisphosphate = D-glyceraldehyde 3-phosphate + dihydroxyacetone phosphate.", "evidence": [ { "id": "A0A8V1AIR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIR0" } ] }, { "ec_number": "4.1.2.13", "activity": "", "evidence": [ { "id": "A0A8V1AIR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIR0" } ] } ] }, { "uniprot_ac": "A0A8V1AMW1", "gene_name": "CANT1", "activity": [ { "ec_number": "3.6.1.6", "activity": "a ribonucleoside 5'-diphosphate + H2O = a ribonucleoside 5'-phosphate + phosphate + H(+).", "evidence": [ { "id": "A0A8V1AMW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMW1" } ] }, { "ec_number": "3.6.1.6", "activity": "", "evidence": [ { "id": "A0A8V1AMW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMW1" } ] } ] }, { "uniprot_ac": "A2JDL7", "gene_name": "LOC121107389", "activity": [ { "ec_number": "3.4.21.4", "activity": "Preferential cleavage: Arg-|-Xaa, Lys-|-Xaa.", "evidence": [ { "id": "A2JDL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2JDL7" } ] }, { "ec_number": "3.4.21.4", "activity": "", "evidence": [ { "id": "A2JDL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2JDL7" } ] } ] }, { "uniprot_ac": "E1BRQ8", "gene_name": "DUSP15", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "E1BRQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BRQ8" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "E1BRQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BRQ8" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "E1BRQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BRQ8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "E1BRQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BRQ8" } ] } ] }, { "uniprot_ac": "E1C9D9", "gene_name": "MMP1", "activity": [ { "ec_number": "3.4.24.7", "activity": "Cleavage of the triple helix of collagen at about three-quarters of the length of the molecule from the N-terminus, at 775-Gly-|-Ile-776 in the alpha1(I) chain. Cleaves synthetic substrates and alpha-macroglobulins at bonds where P1' is a hydrophobic residue.", "evidence": [ { "id": "E1C9D9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C9D9" } ] }, { "ec_number": "3.4.24.7", "activity": "", "evidence": [ { "id": "E1C9D9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C9D9" } ] } ] }, { "uniprot_ac": "F1N842", "gene_name": "DUSP12", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1N842", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N842" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1N842", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N842" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1N842", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N842" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1N842", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N842" } ] } ] }, { "uniprot_ac": "F1NAX3", "gene_name": "PGP", "activity": [ { "ec_number": "3.1.3.21", "activity": "sn-glycerol 1-phosphate + H2O = glycerol + phosphate.", "evidence": [ { "id": "F1NAX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NAX3" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1NAX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NAX3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1NAX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NAX3" } ] }, { "ec_number": "3.1.3.21", "activity": "", "evidence": [ { "id": "F1NAX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NAX3" } ] } ] }, { "uniprot_ac": "F1NCC5", "gene_name": "DUSP4", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1NCC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCC5" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1NCC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCC5" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1NCC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCC5" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1NCC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCC5" } ] } ] }, { "uniprot_ac": "F1NN63", "gene_name": "PGM1", "activity": [ { "ec_number": "5.4.2.2", "activity": "alpha-D-glucose 1-phosphate = alpha-D-glucose 6-phosphate.", "evidence": [ { "id": "F1NN63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NN63" } ] }, { "ec_number": "5.4.2.2", "activity": "", "evidence": [ { "id": "F1NN63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NN63" } ] } ] }, { "uniprot_ac": "F1NVR5", "gene_name": "PTPN14", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1NVR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVR5" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1NVR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVR5" } ] } ] }, { "uniprot_ac": "F1NWE3", "gene_name": "PTPRS", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1NWE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NWE3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1NWE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NWE3" } ] } ] }, { "uniprot_ac": "F1P225", "gene_name": "LOC423731", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1P225", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P225" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1P225", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P225" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1P225", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P225" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1P225", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P225" } ] } ] }, { "uniprot_ac": "O13016", "gene_name": "PTPN1", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "O13016", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O13016" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "O13016", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O13016" } ] } ] }, { "uniprot_ac": "P00698", "gene_name": "LYZ", "activity": [ { "ec_number": "3.2.1.17", "activity": "Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins.", "evidence": [ { "id": "P00698", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00698" } ] }, { "ec_number": "3.2.1.17", "activity": "", "evidence": [ { "id": "P00698", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00698" } ] } ] }, { "uniprot_ac": "P08267", "gene_name": "FTH", "activity": [ { "ec_number": "1.16.3.1", "activity": "4 Fe(2+) + O2 + 4 H(+) = 4 Fe(3+) + 2 H2O.", "evidence": [ { "id": "P08267", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P08267" } ] }, { "ec_number": "1.16.3.1", "activity": "", "evidence": [ { "id": "P08267", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P08267" } ] } ] }, { "uniprot_ac": "P0C597", "gene_name": "DUSP29", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P0C597", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P0C597" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P0C597", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P0C597" } ] } ] }, { "uniprot_ac": "Q05744", "gene_name": "CTSD", "activity": [ { "ec_number": "3.4.23.5", "activity": "Specificity similar to, but narrower than, that of pepsin A. Does not cleave the 4-Gln-|-His-5 bond in B chain of insulin.", "evidence": [ { "id": "Q05744", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q05744" } ] }, { "ec_number": "3.4.23.5", "activity": "", "evidence": [ { "id": "Q05744", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q05744" } ] } ] }, { "uniprot_ac": "Q08156", "gene_name": "KIT", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q08156", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08156" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "Q08156", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08156" } ] } ] }, { "uniprot_ac": "Q5F4B1", "gene_name": "PGP", "activity": [ { "ec_number": "3.1.3.21", "activity": "sn-glycerol 1-phosphate + H2O = glycerol + phosphate.", "evidence": [ { "id": "Q5F4B1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F4B1" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q5F4B1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F4B1" } ] }, { "ec_number": "3.1.3.18", "activity": "2-phosphoglycolate + H2O = glycolate + phosphate.", "evidence": [ { "id": "Q5F4B1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F4B1" } ] }, { "ec_number": "3.1.3.18", "activity": "", "evidence": [ { "id": "Q5F4B1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F4B1" } ] } ] }, { "uniprot_ac": "Q5ZKG5", "gene_name": "ACP1", "activity": [ { "ec_number": "3.1.3.2", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "Q5ZKG5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKG5" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q5ZKG5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKG5" } ] }, { "ec_number": "3.1.3.2", "activity": "", "evidence": [ { "id": "Q5ZKG5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKG5" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q5ZKG5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKG5" } ] } ] }, { "uniprot_ac": "Q6YI48", "gene_name": "PTPRU", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q6YI48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6YI48" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q6YI48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6YI48" } ] } ] }, { "uniprot_ac": "Q8QFM7", "gene_name": "PTGDS", "activity": [ { "ec_number": "5.3.99.2", "activity": "prostaglandin H2 = prostaglandin D2.", "evidence": [ { "id": "Q8QFM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8QFM7" } ] }, { "ec_number": "5.3.99.2", "activity": "", "evidence": [ { "id": "Q8QFM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8QFM7" } ] } ] }, { "uniprot_ac": "Q90629", "gene_name": "", "activity": [ { "ec_number": "3.4.21.4", "activity": "Preferential cleavage: Arg-|-Xaa, Lys-|-Xaa.", "evidence": [ { "id": "Q90629", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q90629" } ] }, { "ec_number": "3.4.21.4", "activity": "", "evidence": [ { "id": "Q90629", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q90629" } ] } ] }, { "uniprot_ac": "Q90687", "gene_name": "PTPN11", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q90687", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q90687" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q90687", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q90687" } ] } ] }, { "uniprot_ac": "Q98936", "gene_name": "PTPRG", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q98936", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q98936" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q98936", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q98936" } ] } ] }, { "uniprot_ac": "Q9PW71", "gene_name": "DUSP4", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q9PW71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9PW71" } ] }, { "ec_number": "3.1.3.48", "activity": 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"RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q2UE42", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UE42", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2UE42-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UE42-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZGP0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGP0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZGP0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGP0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMP0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMP0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMP0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMP0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSEESEESVPLLALQQESMASALFNTDQNDNSERRRHDNSERRRNDNPGSETNGQPQNNIQQVVDQDEEEDEELTLKYGAKHVIMLFVPVTLCMVVVVATIKSVSFYTRKDGQLIYTPFTEETDTIGQRALNSILNAAIMISVIIVMTILLVVLYKYRCYKVIHGWLIISSLLLLFFFSFIYLGEVFKTYNVAMDYITVALIIWNFGVVGMICIHWKGPLRLQQAYLIMISALMALVFIKYLPEWTAWLILAVISVYDLVAVLCPKGPLRMLVETAQERNETLFPALIYSSTMVWLVNMAEEDPEGQRKASKNSTYDKQAPANQSQNEDAEADDGGFSQEWQQQRDNRIGPIESTPESRAAVQALPSNSQTSEDPEERGVKLGLGDFIFYSVLVGKASATASGDWNTTLACFVAILIGLCLTLLLLAIFKKALPALPISITFGLVFYFATDNLVQPFMDQLAFHQFYI", "length": 468, "header": "tr|A0A3Q2UE42-1|A0A3Q2UE42_CHICK Isoform 1 of Presenilin OS=Gallus gallus OX=9031 GN=PSEN1 PE=3 SV=1 CANONICAL=A0A3Q2UE42-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2UE42-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UE42/entry#A0A3Q2UE42-1", "sequence": { "sequence": "MSEESEESVPLLALQQESMASALFNTDQNDNSERRRHDNSERRRNDNPGSETNGQPQNNIQQVVDQDEEEDEELTLKYGAKHVIMLFVPVTLCMVVVVATIKSVSFYTRKDGQLIYTPFTEETDTIGQRALNSILNAAIMISVIIVMTILLVVLYKYRCYKVIHGWLIISSLLLLFFFSFIYLGEVFKTYNVAMDYITVALIIWNFGVVGMICIHWKGPLRLQQAYLIMISALMALVFIKYLPEWTAWLILAVISVYDLVAVLCPKGPLRMLVETAQERNETLFPALIYSSTMVWLVNMAEEDPEGQRKASKNSTYDKQAPANQSQNEDAEADDGGFSQEWQQQRDNRIGPIESTPESRAAVQALPSNSQTSEDPEERGVKLGLGDFIFYSVLVGKASATASGDWNTTLACFVAILIGLCLTLLLLAIFKKALPALPISITFGLVFYFATDNLVQPFMDQLAFHQFYI", "length": 468, "header": "tr|A0A3Q2UE42-1|A0A3Q2UE42_CHICK Isoform 1 of Presenilin OS=Gallus gallus OX=9031 GN=PSEN1 PE=3 SV=1 CANONICAL=A0A3Q2UE42-1" }, "locus": { "chromosome": "5", "start_pos": 25906429, "end_pos": 25890336, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050722.1", "url": "https://www.ensembl.org/id/ENSGALT00010050722.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029948.1", "url": "https://www.ensembl.org/id/ENSGALP00010029948.1" } ] } }, { "isoform_ac": "A0A8V0ZGP0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UE42/entry#A0A8V0ZGP0-1", "sequence": { "sequence": "MTELSAHLPQFQHGQMTENFPDNHLSNTNDNSERRRHDNSERRRNDNPGSETNGQPQNNIQQVVDQDEEEDEELTLKYGAKHVIMLFVPVTLCMVVVVATIKSVSFYTRKDGQLIYTPFTEETDTIGQRALNSILNAAIMISVIIVMTILLVVLYKYRCYKVIHGWLIISSLLLLFFFSFIYLGEVFKTYNVAMDYITVALIIWNFGVVGMICIHWKGPLRLQQAYLIMISALMALVFIKYLPEWTAWLILAVISVYDLVAVLCPKGPLRMLVETAQERNETLFPALIYSSTMVWLVNMAEEDPEGQRKASKNSTYDKQAPANQSQNEDAEADDGGFSQEWQQQRDNRIGPIESTPESRAAVQALPSNSQTSEDPEERGVKLGLGDFIFYSVLVGKASATASGDWNTTLACFVAILIHWGFNLEQKDERSPGTVVAKVYDAVISVDGY", "length": 448, "header": "tr|A0A8V0ZGP0-1|A0A3Q2UE42_CHICK Computationally mapped isoform of Presenilin OS=Gallus gallus OX=9031 GN=PSEN1 PE=3 SV=1 CANONICAL=A0A3Q2UE42-1" }, "locus": { "chromosome": "5", "start_pos": 25908302, "end_pos": 25887018, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050723.1", "url": "https://www.ensembl.org/id/ENSGALT00010050723.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029949.1", "url": "https://www.ensembl.org/id/ENSGALP00010029949.1" } ] } }, { "isoform_ac": "A0A8V0ZMP0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UE42/entry#A0A8V0ZMP0-1", "sequence": { "sequence": "MSEESEESVPLLALQQESMASALFNTDQNDNSERRRHDNSERRRNDNPGSETNGQPQNNIQQVVDQDEEEDEELTLKYGAKHVIMLFVPVTLCMVVVVATIKSVSFYTRKDGQLIYTPFTEETDTIGQRALNSILNAAIMISVIIVMTILLVVLYKYRCYKVIHGWLIISSLLLLFFFSFIYLGEVFKTYNVAMDYITVALIIWNFGVVGMICIHWKGPLRLQQAYLIMISALMALVFIKYLPEWTAWLILAVISVYDLVAVLCPKGPLRMLVETAQERNETLFPALIYSSTMVWLVNMAEEDPEGQRKASKNSTYDKQAPANQSQNEDAEADDGGFSQEWQQQRDNRIGPIESTPESRAAVQALPSNSQTSEDPEERVKLGLGDFIFYSVLVGKASATASGDWNTTLACFVAILIHWGFNLEQKDERSPGTVVAKVYDAVISVDGY", "length": 447, "header": "tr|A0A8V0ZMP0-1|A0A3Q2UE42_CHICK Computationally mapped isoform of Presenilin OS=Gallus gallus OX=9031 GN=PSEN1 PE=3 SV=1 CANONICAL=A0A3Q2UE42-1" }, "locus": { "chromosome": "5", "start_pos": 25906429, "end_pos": 25887018, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050718.1", "url": "https://www.ensembl.org/id/ENSGALT00010050718.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029947.1", "url": "https://www.ensembl.org/id/ENSGALP00010029947.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-GGA-1251985", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1251985", "resource": "Reactome", "description": "Nuclear signaling by ERBB4" }, { "id": "R-GGA-193692", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-193692", "resource": "Reactome", "description": "Regulated proteolysis of p75NTR" }, { "id": "R-GGA-205043", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-205043", "resource": "Reactome", "description": "NRIF signals cell death from the nucleus" }, { "id": "R-GGA-3928665", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3928665", "resource": "Reactome", "description": "EPH-ephrin mediated repulsion of cells" }, { "id": "R-GGA-6798695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798695", "resource": "Reactome", "description": "Neutrophil degranulation" }, { "id": "R-GGA-9013507", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013507", "resource": "Reactome", "description": "NOTCH3 Activation and Transmission of Signal to the Nucleus" }, { "id": "R-GGA-9017802", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9017802", "resource": "Reactome", "description": "Noncanonical activation of NOTCH3" }, { "id": "R-GGA-9839383", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9839383", "resource": "Reactome", "description": "TGFBR3 PTM regulation" } ], "orthologs": [ { "uniprot_canonical_ac": "G3HNF2-1", "protein_name": "Presenilin", "gene_name": "Psen1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MTEIPAPLSYFQNAQMSEDSHSSSTVRSQSDSQDRQQHHDRRRLDNPEPVSNGRPQSHSRQVVEQDEEEDEELTLKYGAKHVIMLFVPVTLCMVVVVATIKSVSFYTRKDGQLIYTPFTEDTETVGQRALHSILNAAIMISVIVVMTILLVVLYKYRCYKVIHAWLIVSSLLLLFFFSFIYLGEVFKTYNVAVDYITVALLIWNFGVVGMIAIHWKGPLRLQQAYLIMISALMALVFIKYLPEWTAWLILAVISVYDLVAVLCPKGPLRMLVETAQERNETLFPALIYSSTMVWLVNMAEGDPEAQRRVPKNPKYNAQRAERERQDSSTGNDDGGFSEEWEAQRDSHLGPHRSTPESRAAVQELSSSILTNEDPEERGVKLGLGDFIFYSVLVGKASATASGDWNTTIACFVAILIGLCLTLLLLAIFKKALPALPISITFGLVFYFATDYLVQPFMDQLAFHQFYI", "length": 467 }, "evidence": [ { "id": "A0A3Q2UE42", "url": "https://omabrowser.org/oma/group/A0A3Q2UE42/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P49768-1", "protein_name": "Presenilin-1", "gene_name": "PSEN1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTELPAPLSYFQNAQMSEDNHLSNTVRSQNDNRERQEHNDRRSLGHPEPLSNGRPQGNSRQVVEQDEEEDEELTLKYGAKHVIMLFVPVTLCMVVVVATIKSVSFYTRKDGQLIYTPFTEDTETVGQRALHSILNAAIMISVIVVMTILLVVLYKYRCYKVIHAWLIISSLLLLFFFSFIYLGEVFKTYNVAVDYITVALLIWNFGVVGMISIHWKGPLRLQQAYLIMISALMALVFIKYLPEWTAWLILAVISVYDLVAVLCPKGPLRMLVETAQERNETLFPALIYSSTMVWLVNMAEGDPEAQRRVSKNSKYNAESTERESQDTVAENDDGGFSEEWEAQRDSHLGPHRSTPESRAAVQELSSSILAGEDPEERGVKLGLGDFIFYSVLVGKASATASGDWNTTIACFVAILIGLCLTLLLLAIFKKALPALPISITFGLVFYFATDYLVQPFMDQLAFHQFYI", "length": 467 }, "evidence": [ { "id": "A0A3Q2UE42", "url": "https://omabrowser.org/oma/group/A0A3Q2UE42/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P97887-1", "protein_name": "Presenilin-1", "gene_name": "Psen1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTEIPAPLSYFQNAQMSEDSHSSSVRSQNDNQERQQHHDRQRLDNPESISNGRPQSNFTRQVIEQDEEEDEELTLKYGAKHVIMLFVPVTLCMVVVVATIKSVSFYTRKDGQLIYTPFTEDTETVGQRALHSILNAAIMISVIVVMTILLVVLYKYRCYKVIHAWLIVSSLLLLFFFSFIYLGEVFKTYNVAVDYITVALLIWNFGVVGMIAIHWKGPLRLQQAYLIMISALMALVFIKYLPEWTAWLILAVISVYDLVAVLCPKGPLRMLVETAQERNETLFPALIYSSTMVWLVNMAEGDPEAQRRVPKNPKYSTQGTEREETQDTGTGSDDGGFSEEWEAQRDSHLGPHRSTPESRAAVQELSGSILTSEDPEERGVKLGLGDFIFYSVLVGKASATASGDWNTTIACFVAILIGLCLTLLLLAIFKKALPALPISITFGLIFYFATDYLVQPFMDQLAFHQFYI", "length": 468 }, "evidence": [ { "id": "A0A3Q2UE42", "url": "https://omabrowser.org/oma/group/A0A3Q2UE42/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9SIK7-1", "protein_name": "Presenilin-like protein At2g29900", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDRNQRPRSILDSLGEELIAILTPVSICMFTVVLLVCILNSDPSSSSASFSSIATAAYSESDSDSSWDKFVGALLNSVVFVAAITVATFVLVLLFYLRCVKFLKFYMGFSAFIVLGNLGGEILVLLIDRFRFPIDSITFLILLFNFSVVGVFAVFMSKFSILITQGYLVWIGVLVAYFFTLLPEWTTWVLLVALALYDIAAVLLPVGPLRLLVEMAISRDEDIPALVYEARPVIRNDSRSVQRRVWREQRSSQNNANRNEVRVVESAEVEEEHVGSSERAEISVPLIDRRPEQAENSETFLEGIGLGSSGAIKLGLGDFIFYSVLVGRAAMYDLMTVYACYLAIIAGLGITLMLLSVYQKALPALPVSIMLGVVFYFLARLLLEVFVVQCSSNLVMF", "length": 397 }, "evidence": [ { "id": "A0A3Q2UE42", "url": "https://omabrowser.org/oma/group/A0A3Q2UE42/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 23, "go_terms": [ { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UE42", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UE42" } ], "pmid": "" }, { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UE42", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UE42" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UE42", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UE42" } ], "pmid": "" }, { "name": "smooth endoplasmic reticulum", "id": "GO:0005790", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005790", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UE42", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UE42" } ], "pmid": "" }, { "name": "rough endoplasmic reticulum", "id": "GO:0005791", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005791", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UE42", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UE42" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UE42", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UE42" } ], "pmid": "" }, { "name": "cell cortex", "id": "GO:0005938", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005938", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UE42", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UE42" } ], "pmid": "" }, { "name": "growth cone", "id": "GO:0030426", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030426", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UE42", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UE42" } ], "pmid": "" }, { "name": "ciliary rootlet", "id": "GO:0035253", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035253", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UE42", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UE42" } ], "pmid": "" }, { "name": "neuronal cell body", "id": "GO:0043025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043025", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UE42", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UE42" } ], "pmid": "" }, { "name": "dendritic shaft", "id": "GO:0043198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043198", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UE42", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UE42" } ], "pmid": "" }, { "name": "membrane raft", "id": "GO:0045121", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045121", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UE42", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UE42" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UE42", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UE42" } ], "pmid": "" }, { "name": "cytoplasmic vesicle", "id": "GO:0031410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031410", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UE42", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UE42" } ], "pmid": "" }, { "name": "postsynapse", "id": "GO:0098794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098794", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UE42", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UE42" } ], "pmid": "" }, { "name": "mitochondria-associated endoplasmic reticulum membrane contact site", "id": "GO:0044233", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044233", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UE42", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UE42" } ], "pmid": "" }, { "name": "kinetochore", "id": "GO:0000776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000776", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UE42", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UE42" } ], "pmid": "" }, { "name": "gamma-secretase complex", "id": "GO:0070765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070765", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UE42", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UE42" } ], "pmid": "" }, { "name": "nuclear outer membrane", "id": "GO:0005640", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005640", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UE42", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UE42" } ], "pmid": "" }, { "name": "aggresome", "id": "GO:0016235", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016235", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UE42", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UE42" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UE42", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UE42" } ], "pmid": "" }, { "name": "axon", "id": "GO:0030424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030424", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UE42", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UE42" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UE42", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UE42" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 8, "go_terms": [ { "name": "molecular adaptor activity", "id": "GO:0060090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060090", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UE42", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UE42" } ], "pmid": "" }, { "name": "calcium channel activity", "id": "GO:0005262", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005262", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UE42", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UE42" } ], "pmid": "" }, { "name": "ATPase binding", "id": "GO:0051117", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051117", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UE42", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UE42" } ], "pmid": "" }, { "name": "growth factor receptor binding", "id": "GO:0070851", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070851", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UE42", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UE42" } ], "pmid": "" }, { "name": "cadherin binding", "id": "GO:0045296", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045296", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UE42", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UE42" } ], "pmid": "" }, { "name": "PDZ domain binding", "id": "GO:0030165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030165", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UE42", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UE42" } ], "pmid": "" }, { "name": "beta-catenin binding", "id": "GO:0008013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008013", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UE42", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UE42" } ], "pmid": "" }, { "name": "aspartic endopeptidase activity, intramembrane cleaving", "id": "GO:0042500", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042500", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UE42", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UE42" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 33, "go_terms": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UE42", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UE42" } ], "pmid": "" }, { "name": "astrocyte activation involved in immune response", "id": "GO:0002265", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002265", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UE42", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UE42" } ], "pmid": "" }, { "name": "membrane protein ectodomain proteolysis", "id": "GO:0006509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006509", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UE42", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UE42" } ], "pmid": "" }, { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UE42", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UE42" } ], "pmid": "" }, { "name": "Notch signaling pathway", "id": "GO:0007219", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007219", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UE42", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UE42" } ], "pmid": "" }, { "name": "Notch receptor processing", "id": "GO:0007220", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007220", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UE42", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UE42" } ], "pmid": "" }, { "name": "memory", "id": "GO:0007613", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007613", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UE42", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UE42" } ], "pmid": "" }, { "name": "negative regulation of gene expression", "id": "GO:0010629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010629", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UE42", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UE42" } ], "pmid": "" }, { "name": "protein processing", "id": "GO:0016485", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016485", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UE42", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UE42" } ], "pmid": "" }, { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UE42", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UE42" } ], "pmid": "" }, { "name": "negative regulation of apoptotic process", "id": "GO:0043066", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043066", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UE42", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UE42" } ], "pmid": "" }, { "name": "synapse organization", "id": "GO:0050808", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050808", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UE42", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UE42" } ], "pmid": "" }, { "name": "cellular response to amyloid-beta", "id": "GO:1904646", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904646", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UE42", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UE42" } ], "pmid": "" }, { "name": "positive regulation of amyloid fibril formation", "id": "GO:1905908", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905908", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UE42", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UE42" } ], "pmid": "" }, { "name": "neuron projection maintenance", "id": "GO:1990535", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990535", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UE42", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UE42" } ], "pmid": "" }, { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UE42", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UE42" } ], "pmid": "" }, { "name": "DNA damage response", "id": "GO:0006974", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006974", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UE42", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UE42" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UE42", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UE42" } ], "pmid": "" }, { "name": "positive regulation of tumor necrosis factor production", "id": "GO:0032760", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032760", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UE42", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UE42" } ], "pmid": "" }, { "name": "positive regulation of glycolytic process", "id": "GO:0045821", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045821", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UE42", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UE42" } ], "pmid": "" }, { "name": "positive regulation of receptor recycling", "id": "GO:0001921", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001921", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UE42", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UE42" } ], "pmid": "" }, { "name": "regulation of canonical Wnt signaling pathway", "id": "GO:0060828", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060828", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UE42", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UE42" } ], "pmid": "" }, { "name": "positive regulation of proteasomal ubiquitin-dependent protein catabolic process", "id": "GO:0032436", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032436", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UE42", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UE42" } ], "pmid": "" }, { "name": "regulation of neuron projection development", "id": "GO:0010975", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010975", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UE42", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UE42" } ], "pmid": "" }, { "name": "amyloid-beta formation", "id": "GO:0034205", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034205", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UE42", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UE42" } ], "pmid": "" }, { "name": "calcium ion homeostasis", "id": "GO:0055074", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055074", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UE42", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UE42" } ], "pmid": "" }, { "name": "positive regulation of dendritic spine development", "id": "GO:0060999", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060999", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UE42", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UE42" } ], "pmid": "" }, { "name": "negative regulation of ubiquitin-dependent protein catabolic process", "id": "GO:2000059", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000059", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UE42", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UE42" } ], "pmid": "" }, { "name": "skin morphogenesis", "id": "GO:0043589", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043589", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UE42", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UE42" } ], "pmid": "" }, { "name": "regulation of synaptic vesicle cycle", "id": "GO:0098693", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098693", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UE42", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UE42" } ], "pmid": "" }, { "name": "regulation of postsynapse organization", "id": "GO:0099175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099175", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UE42", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UE42" } ], "pmid": "" }, { "name": "protein catabolic process at postsynapse", "id": "GO:0140249", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140249", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UE42", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UE42" } ], "pmid": "" }, { "name": "amyloid precursor protein catabolic process", "id": "GO:0042987", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042987", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UE42", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UE42" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 280, "end_pos": 282, "annotation": "n_glycosylation_sequon" }, { "start_pos": 313, "end_pos": 315, "annotation": "n_glycosylation_sequon" }, { "start_pos": 323, "end_pos": 325, "annotation": "n_glycosylation_sequon" }, { "start_pos": 406, "end_pos": 408, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-GGA-1251997", "name": "Cleavage of ERBB4m80 by gamma-scretase complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0Z5X8-1", "A0A3Q2UE42-1", "A0A8V0YIT6-1" ], "evidence": [ { "id": "R-GGA-1251997", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1251997" } ] }, { "id": "R-GGA-193682", "name": "gamma-secretase cleaves the p75NTR transmembrane domain", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "early endosome, plasma membrane", "input_participant_list": [], "output_participant_list": [ "R-GGA-194509" ], "enzyme_list": [ "A0A8V0Z5X8-1", "A0A3Q2UE42-1" ], "evidence": [ { "id": "R-GGA-193682", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-193682" } ] }, { "id": "R-GGA-205112", "name": "gamma-secretase cleaves p75NTR, releasing NRIF and TRAF6", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0Z5X8-1", "A0A3Q2UE42-1", "E1C626-1" ], "evidence": [ { "id": "R-GGA-205112", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-205112" } ] }, { "id": "R-GGA-3928656", "name": "gamma-secretase cleaves EPHB2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0Z5X8-1", "A0A8V0ZRU7-1", "A0A8V1A2E6-1", "A0A8V0YUC4-1", "A0A8V0YZP9-1", "A0A3Q2UE42-1" ], "evidence": [ { "id": "R-GGA-3928656", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3928656" } ] }, { "id": "R-GGA-6798739", "name": "Exocytosis of azurophil granule membrane proteins", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane, azurophil granule membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q2U2N5-1", "Q98932-1", "A0A1D5PVG8-1", "Q5ZHX1-1", "A0A8V1AN75-1", "A0A8V0Z1E9-1", "A0A8V0YYJ1-1", "A0A8V0ZEG9-1", "A0A3Q2UE42-1", "A0A8V0Y298-1", "A0A8V0YGN2-1" ], "evidence": [ { "id": "R-GGA-6798739", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798739" } ] }, { "id": "R-GGA-9013361", "name": "NEXT3 is cleaved to produce NICD3", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [ "R-GGA-157203" ], "output_participant_list": [ "R-GGA-157647", "R-GGA-157657" ], "enzyme_list": [ "A0A8V0Z5X8-1", "A0A3Q2UE42-1" ], "evidence": [ { "id": "R-GGA-9013361", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013361" } ] }, { "id": "R-GGA-9017817", "name": "Gamma-secretase cleaves YBX1:NOTCH3", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0Z5X8-1", "A0A3Q2UE42-1" ], "evidence": [ { "id": "R-GGA-9017817", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9017817" } ] }, { "id": "R-GGA-9839376", "name": "TGFBR3(784-851) degradation", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytoplasmic side of plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0Z5X8-1", "A0A3Q2UE42-1" ], "evidence": [ { "id": "R-GGA-9839376", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9839376" } ] } ], "reaction_participants": [ { "participant_id": "R-GGA-157203", "participant_name": "NEXT3 [plasma membrane]", "crossref": [ { "id": "A0A8V1AHH1", "database": "UniProt", "url": "" }, { "id": "ENSGALP00010041847", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALT00010068104", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALG00010028107", "database": "ENSEMBL", "url": "" } ] }, { "participant_id": "R-GGA-157647", "participant_name": "NICD3 [cytosol]", "crossref": [ { "id": "A0A8V1AHH1", "database": "UniProt", "url": "" }, { "id": "ENSGALT00010068104", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALG00010028107", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALP00010041847", "database": "ENSEMBL", "url": "" } ] }, { "participant_id": "R-GGA-157657", "participant_name": "NOTCH3(1629-1661) [plasma membrane]", "crossref": [ { "id": "A0A8V1AHH1", "database": "UniProt", "url": "" }, { "id": "ENSGALT00010068104", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALG00010028107", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALP00010041847", "database": "ENSEMBL", "url": "" } ] }, { "participant_id": "R-GGA-194509", "participant_name": "NGFR [plasma membrane]", "crossref": [ { "id": "ENSGALP00010036051", "database": "ENSEMBL", "url": "" }, { "id": "A0A8V1A445", "database": "UniProt", "url": "" }, { "id": "ENSGALG00010024218", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALT00010059091", "database": "ENSEMBL", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5PVG8", "gene_name": "PRCP", "activity": [ { "ec_number": "3.4.16.2", "activity": "Cleavage of a 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"https://www.ebi.ac.uk/interpro/entry/IPR019762", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020850", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020850", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022812", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022812", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030381", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030381", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045063", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045063", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2UHM4", "url": "https://www.orthodb.org/?gene=A0A3Q2UHM4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y8A4", "url": "https://www.orthodb.org/?gene=A0A8V0Y8A4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YGP7", "url": "https://www.orthodb.org/?gene=A0A8V0YGP7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11566", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11566", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11566:SF39", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11566:SF39", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00350", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00350", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01031", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01031", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02212", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02212", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-75153", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-75153", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015141156", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015141156", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "19669", "url": "https://www.rhea-db.org/rhea/19669", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q2UHM4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UHM4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2UHM4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UHM4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y8A4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8A4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y8A4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8A4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGP7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGP7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGP7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGP7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEALIPVINKLQDVFNTVGADIIQLPQIVVVGTQSSGKSSVLESLVGRDLLPRGTGVVTRRPLILQLVHVSPEDGRKTAGDENDPATWKNPRHLSKEIDAEEWGKFLHTKNKIYTDFDEIRQEIENETERISGNNKGISPEPIHLKIFSSNVVNLTLVDLPGMTKVPVGDQPKDIELQIRELILQFISNPNSIILAVTAANTDMATSEALKIAREVDPDGRRTLAVITKLDLMDAGTDAMDVLMGRVIPVKLGIIGVVNRSQLDINNKKSVADSIRDEYGFLQKKYPSLANRNGTKYLARTLNRLLMHHIRDCLPELKTRINVLAAQYQSLLNSYGEPVEDKSATLLQLITKFATEYCNTIEGTAKYIETSELCGGARICYIFHETFGRTLESVDPLGGLNTIDILTAIRNATGPRPALFVPEVSFELLVKRQIKRLEEPSLRCVELVHEEMQRIIQHCSNYSTQELLRFPKLHDAIVEVVTCLLRRRLPVTNEMVHNLVAIELAYINTKHPDFADACGLMNNNIEEQRRNRLARELPSSVPRDKSTKAPGALPPASQETVTAASAEADGKAAAGAGDVTQESGTGNWRGMLKSSKAEEVSAEEKSKPAAALPASPQKGHAVNLLDVPVPVARKLSAREQRDCEVIERLIKSYFLIVRKNIQDSVPKAVMHFLVNHVKDTLQSELVGQLYKSLLLDDLLTESEDMAQRRKEAADMLKALQRASQIIAEIRETHLW", "length": 735, "header": "tr|A0A3Q2UHM4-1|A0A3Q2UHM4_CHICK Isoform 1 of Dynamin-1-like protein OS=Gallus gallus OX=9031 GN=DNM1L PE=1 SV=1 CANONICAL=A0A3Q2UHM4-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2UHM4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UHM4/entry#A0A3Q2UHM4-1", "sequence": { "sequence": "MEALIPVINKLQDVFNTVGADIIQLPQIVVVGTQSSGKSSVLESLVGRDLLPRGTGVVTRRPLILQLVHVSPEDGRKTAGDENDPATWKNPRHLSKEIDAEEWGKFLHTKNKIYTDFDEIRQEIENETERISGNNKGISPEPIHLKIFSSNVVNLTLVDLPGMTKVPVGDQPKDIELQIRELILQFISNPNSIILAVTAANTDMATSEALKIAREVDPDGRRTLAVITKLDLMDAGTDAMDVLMGRVIPVKLGIIGVVNRSQLDINNKKSVADSIRDEYGFLQKKYPSLANRNGTKYLARTLNRLLMHHIRDCLPELKTRINVLAAQYQSLLNSYGEPVEDKSATLLQLITKFATEYCNTIEGTAKYIETSELCGGARICYIFHETFGRTLESVDPLGGLNTIDILTAIRNATGPRPALFVPEVSFELLVKRQIKRLEEPSLRCVELVHEEMQRIIQHCSNYSTQELLRFPKLHDAIVEVVTCLLRRRLPVTNEMVHNLVAIELAYINTKHPDFADACGLMNNNIEEQRRNRLARELPSSVPRDKSTKAPGALPPASQETVTAASAEADGKAAAGAGDVTQESGTGNWRGMLKSSKAEEVSAEEKSKPAAALPASPQKGHAVNLLDVPVPVARKLSAREQRDCEVIERLIKSYFLIVRKNIQDSVPKAVMHFLVNHVKDTLQSELVGQLYKSLLLDDLLTESEDMAQRRKEAADMLKALQRASQIIAEIRETHLW", "length": 735, "header": "tr|A0A3Q2UHM4-1|A0A3Q2UHM4_CHICK Isoform 1 of Dynamin-1-like protein OS=Gallus gallus OX=9031 GN=DNM1L PE=1 SV=1 CANONICAL=A0A3Q2UHM4-1" }, "locus": { "chromosome": "1", "start_pos": 58994552, "end_pos": 58960574, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026626.1", "url": "https://www.ensembl.org/id/ENSGALT00010026626.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015183.1", "url": "https://www.ensembl.org/id/ENSGALP00010015183.1" } ] } }, { "isoform_ac": "A0A8V0Y8A4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UHM4/entry#A0A8V0Y8A4-1", "sequence": { "sequence": "MEALIPVINKLQDVFNTVGADIIQLPQIVVVGTQSSGKSSVLESLVGRDLLPRGTGVVTRRPLILQLVHVSPEDGRKTAGDENEIDAEEWGKFLHTKNKIYTDFDEIRQEIENETERISGNNKGISPEPIHLKIFSSNVVNLTLVDLPGMTKVPVGDQPKDIELQIRELILQFISNPNSIILAVTAANTDMATSEALKIAREVDPDGRRTLAVITKLDLMDAGTDAMDVLMGRVIPVKLGIIGVVNRSQLDINNKKSVADSIRDEYGFLQKKYPSLANRNGTKYLARTLNRLLMHHIRDCLPELKTRINVLAAQYQSLLNSYGEPVEDKSATLLQLITKFATEYCNTIEGTAKYIETSELCGGARICYIFHETFGRTLESVDPLGGLNTIDILTAIRNATGPRPALFVPEVSFELLVKRQIKRLEEPSLRCVELVHEEMQRIIQHCSNYSTQELLRFPKLHDAIVEVVTCLLRRRLPVTNEMVHNLVAIELAYINTKHPDFADACGLMNNNIEEQRRNRLARELPSSVPRDKSTKAPGALPPASQETVTAASAEADGKAAAGAGDVTQESGTGNWRGMLKSSKAEEVSAEEKSKPAAALPASPQKGHAVNLLDVPVPVARKLSAREQRDCEVIERLIKSYFLIVRKNIQDSVPKAVMHFLVNHVKDTLQSELVGQLYKSLLLDDLLTESEDMAQRRKEAADMLKALQRASQIIAEIRETHLW", "length": 722, "header": "tr|A0A8V0Y8A4-1|A0A3Q2UHM4_CHICK Computationally mapped isoform of Dynamin-1-like protein OS=Gallus gallus OX=9031 GN=DNM1L PE=1 SV=1 CANONICAL=A0A3Q2UHM4-1" }, "locus": { "chromosome": "1", "start_pos": 58994552, "end_pos": 58960574, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026628.1", "url": "https://www.ensembl.org/id/ENSGALT00010026628.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015185.1", "url": "https://www.ensembl.org/id/ENSGALP00010015185.1" } ] } }, { "isoform_ac": "A0A8V0YGP7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UHM4/entry#A0A8V0YGP7-1", "sequence": { "sequence": "MEALIPVINKLQDVFNTVGADIIQLPQIVVVGTQSSGKSSVLESLVGRDLLPRGTGVVTRRPLILQLVHVSPEDGRKTAGDENEIDAEEWGKFLHTKNKIYTDFDEIRQEIENETERISGNNKGISPEPIHLKIFSSNVVNLTLVDLPGMTKVPVGDQPKDIELQIRELILQFISNPNSIILAVTAANTDMATSEALKIAREVDPDGRRTLAVITKLDLMDAGTDAMDVLMGRVIPVKLGIIGVVNRSQLDINNKKSVADSIRDEYGFLQKKYPSLANRNGTKYLARTLNRLLMHHIRDCLPELKTRINVLAAQYQSLLNSYGEPVEDKSATLLQLITKFATEYCNTIEGTAKYIETSELCGGARICYIFHETFGRTLESVDPLGGLNTIDILTAIRNATGPRPALFVPEVSFELLVKRQIKRLEEPSLRCVELVHEEMQRIIQHCSNYSTQELLRFPKLHDAIVEVVTCLLRRRLPVTNEMVHNLVAIELAYINTKHPDFADACGLMNNNIEDIEYFEETEHEQRRNRLARELPSSVPRDKAAAGAGDVTQESGTGNWRGMLKSSKAEEVSAEEKSKPAAALPASPQKGHAVNLLDVPVPVARKLSAREQRDCEVIERLIKSYFLIVRKNIQDSVPKAVMHFLVNHVKDTLQSELVGQLYKSLLLDDLLTESEDMAQRRKEAADMLKALQRASQIIAEIRETHLW", "length": 706, "header": "tr|A0A8V0YGP7-1|A0A3Q2UHM4_CHICK Computationally mapped isoform of Dynamin-1-like protein OS=Gallus gallus OX=9031 GN=DNM1L PE=1 SV=1 CANONICAL=A0A3Q2UHM4-1" }, "locus": { "chromosome": "1", "start_pos": 58994552, "end_pos": 58960574, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026620.1", "url": "https://www.ensembl.org/id/ENSGALT00010026620.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015177.1", "url": "https://www.ensembl.org/id/ENSGALP00010015177.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-GGA-75153", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-75153", "resource": "Reactome", "description": "Apoptotic execution phase" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 18, "go_terms": [ { "name": "mitochondrial membrane fission", "id": "GO:0090149", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090149", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UHM4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UHM4" } ], "pmid": "" }, { "name": "regulation of peroxisome organization", "id": "GO:1900063", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900063", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UHM4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UHM4" } ], "pmid": "" }, { "name": "endocytosis", "id": "GO:0006897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006897", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UHM4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UHM4" } ], "pmid": "" }, { "name": "peroxisome fission", "id": "GO:0016559", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016559", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UHM4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UHM4" } ], "pmid": "" }, { "name": "protein complex oligomerization", "id": "GO:0051259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051259", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UHM4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UHM4" } ], "pmid": "" }, { "name": "heart contraction", "id": "GO:0060047", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060047", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UHM4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UHM4" } ], "pmid": "" }, { "name": "positive regulation of protein secretion", "id": "GO:0050714", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050714", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UHM4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UHM4" } ], "pmid": "" }, { "name": "rhythmic process", "id": "GO:0048511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048511", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UHM4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UHM4" } ], "pmid": "" }, { "name": "mitochondrial fragmentation involved in apoptotic process", "id": "GO:0043653", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043653", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UHM4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UHM4" } ], "pmid": "" }, { "name": "regulation of ATP metabolic process", "id": "GO:1903578", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903578", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UHM4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UHM4" } ], "pmid": "" }, { "name": "metal ion transport", "id": "GO:0030001", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030001", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UHM4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UHM4" } ], "pmid": "" }, { "name": "mitochondrial fission", "id": "GO:0000266", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000266", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UHM4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UHM4" } ], "pmid": "" }, { "name": "intracellular distribution of mitochondria", "id": "GO:0048312", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048312", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UHM4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UHM4" } ], "pmid": "" }, { "name": "positive regulation of mitochondrial fission", "id": "GO:0090141", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090141", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UHM4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UHM4" } ], "pmid": "" }, { "name": "positive regulation of neutrophil chemotaxis", "id": "GO:0090023", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090023", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UHM4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UHM4" } ], "pmid": "" }, { "name": "regulation of mitophagy", "id": "GO:1901524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901524", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UHM4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UHM4" } ], "pmid": "" }, { "name": "mitochondrion distribution", "id": "GO:0048311", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048311", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UHM4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UHM4" } ], "pmid": "" }, { "name": "programmed cell death", "id": "GO:0012501", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012501", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UHM4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UHM4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 15, "go_terms": [ { "name": "mitochondrion-derived vesicle", "id": "GO:0099073", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099073", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UHM4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UHM4" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UHM4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UHM4" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UHM4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UHM4" } ], "pmid": "" }, { "name": "mitochondrial outer membrane", "id": "GO:0005741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005741", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UHM4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UHM4" } ], "pmid": "" }, { "name": "peroxisome", "id": "GO:0005777", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005777", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UHM4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UHM4" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UHM4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UHM4" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UHM4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UHM4" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UHM4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UHM4" } ], "pmid": "" }, { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UHM4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UHM4" } ], "pmid": "" }, { "name": "brush border", "id": "GO:0005903", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005903", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UHM4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UHM4" } ], "pmid": "" }, { "name": "clathrin-coated pit", "id": "GO:0005905", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005905", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UHM4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UHM4" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UHM4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UHM4" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UHM4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UHM4" } ], "pmid": "" }, { "name": "synaptic vesicle membrane", "id": "GO:0030672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030672", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UHM4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UHM4" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UHM4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UHM4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 9, "go_terms": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UHM4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UHM4" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UHM4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UHM4" } ], "pmid": "" }, { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UHM4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UHM4" } ], "pmid": "" }, { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UHM4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UHM4" } ], "pmid": "" }, { "name": "ubiquitin protein ligase binding", "id": "GO:0031625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031625", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UHM4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UHM4" } ], "pmid": "" }, { "name": "lipid binding", "id": "GO:0008289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008289", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UHM4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UHM4" } ], "pmid": "" }, { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UHM4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UHM4" } ], "pmid": "" }, { "name": "GTP-dependent protein binding", "id": "GO:0030742", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030742", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UHM4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UHM4" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UHM4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UHM4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 126, "end_pos": 128, "annotation": "n_glycosylation_sequon" }, { "start_pos": 154, "end_pos": 156, "annotation": "n_glycosylation_sequon" }, { "start_pos": 259, "end_pos": 261, "annotation": "n_glycosylation_sequon" }, { "start_pos": 293, "end_pos": 295, "annotation": "n_glycosylation_sequon" }, { "start_pos": 411, "end_pos": 413, "annotation": "n_glycosylation_sequon" }, { "start_pos": 461, "end_pos": 463, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "19669", "name": "", "equation": "GTP + H2O = GDP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YVX9-1", "F1NSA8-1", "R4GJA4-1", "A0A1L1RKZ0-1", "E1BUS1-1", "Q5ZHW4-1", "Q90694-1", "P08070-1", "P09642-1", "P09643-1", "P09644-1", "P09645-1", "Q5F352-1", "Q5ZMS3-1", "Q90705-1", "Q90835-1", "Q90965-1", "Q98932-1", "A0A3Q2UHM4-1", "Q5ZHX1-1", "A0A1D5PT95-1", "E1BQI2-1", "F1NPF0-1", "A0A8V0XVU5-1", "A0A8V0XBX5-1", "A0A8V0Z564-1", "A0A8V0Y9R6-1", "A0A1D5PM27-1", "A0A8V0Z8U4-1", "A0A8V0ZJW2-1", "A0A8V1ABB1-1", "A0A8V0YDX6-1", "E1BWN3-1", "Q5F499-1", "Q5ZKU5-1", "P02552-1", "P08642-1", "P26990-1", "P42558-1", "Q5F470-1", "Q5ZIT5-1", "Q5ZJN2-1", "P50146-1", "A0A8V0ZNW3-1", "A0A8V0YIM0-1", "A0A8V0ZRZ2-1", "A0A8V1A9Z8-1", "Q1KME6-1", "Q5ZLG1-1", "P84172-1", "A0A8V1ACG4-1", "A0A8V0YTL7-1", "A0A3Q2UG55-1", "A0A8V1AIF5-1", "Q5ZHV1-1", "A0A8V0Z5P2-1", "A0A8V0Y4A4-1", "A0A8V0YA62-1", "A0A8V0YVM3-1", "A0A1D5P1F5-1", "A0A8V1ADZ7-1", "F1NWF1-1", "A0A8V1AP30-1", "A0A8V0XDD5-1", "A0A8V0XMC5-1", "A0A8V0YWW1-1", "A0A8V0ZR14-1", "A0A8V0Y2H3-1", "Q5ZJD3-1", "Q5ZM73-1", "Q5ZM83-1", "A0A8V0YTY9-1", "A0A8V0ZXW3-1", "A0A8V1AHB3-1", "A0A8V0YDI7-1", "A0A1D5NV13-1", "A0A8V0XGK7-1", "A0A8V0YHK2-1", "A0A8V0XC33-1", "A0A8V0XKC3-1", "F1P278-1", "A0A8V0ZG00-1", "A0A8V1AGP3-1", "A0A8V1AN75-1", "A0A8V0Z416-1", "A0A8V1A0V4-1", "A0A8V1A8Q7-1", "A0A8V1ABD3-1", "A0A8V1API8-1", "A0A8V0YIU8-1", "A0A8V0X962-1", "A0A8V1AKH3-1", "P79784-1", "A0A1D5P533-1", "A0A8V1A8I5-1", "A0A8V1AE09-1", "Q9PSX7-1", "Q5ZKR4-1", "A0A8V0YGN8-1", "A0A8V0XNL0-1", "A0A8V0Y3H2-1" ], "evidence": [ { "id": "19669", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/19669" } ] }, { "id": "R-GGA-351948", "name": "Mitochondrial recruitment of Drp1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, mitochondrial outer membrane", "input_participant_list": [ "R-GGA-351943" ], "output_participant_list": [ "R-GGA-351942" ], "enzyme_list": [ "A0A3Q2UHM4-1" ], "evidence": [ { "id": "R-GGA-351948", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-351948" } ] } ], "reaction_participants": [ { "participant_id": "R-GGA-351942", "participant_name": "DNM1L [mitochondrial outer membrane]", "crossref": [ { "id": "ENSGALP00010015183", "database": "ENSEMBL", "url": "" }, { "id": "XP_046763499.1", "database": "RefSeq", "url": "" }, { "id": "A0A3Q2UHM4", "database": "UniProt", "url": "" }, { "id": "XP_015141156.1", "database": "RefSeq", "url": "" }, { "id": "ENSGALT00010026626", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALG00010011130", "database": "ENSEMBL", "url": "" } ] }, { "participant_id": "R-GGA-351943", "participant_name": "DNM1L [cytosol]", "crossref": 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"id": "A0A1D5P1F5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1F5" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A1D5P1F5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1F5" } ] } ] }, { "uniprot_ac": "A0A1D5P533", "gene_name": "RASEF", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5P533", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P533" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A1D5P533", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P533" } ] } ] }, { "uniprot_ac": "A0A1D5PM27", "gene_name": "OPA1", "activity": [ { "ec_number": "3.6.5.5", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5PM27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PM27" } ] }, { "ec_number": "3.6.5.5", "activity": "", "evidence": [ { "id": "A0A1D5PM27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PM27" } ] } ] }, { "uniprot_ac": "A0A1D5PT95", "gene_name": "KRAS", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5PT95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PT95" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A1D5PT95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PT95" } ] } ] }, { "uniprot_ac": "A0A1L1RKZ0", "gene_name": "RASL11AL", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1L1RKZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RKZ0" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A1L1RKZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RKZ0" } ] } ] }, { "uniprot_ac": "A0A3Q2UG55", "gene_name": "RAB9B", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q2UG55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UG55" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A3Q2UG55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UG55" } ] } ] }, { "uniprot_ac": "A0A3Q2UHM4", "gene_name": "DNM1L", "activity": [ { "ec_number": "3.6.5.5", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q2UHM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UHM4" } ] }, { "ec_number": "3.6.5.5", "activity": "", "evidence": [ { "id": "A0A3Q2UHM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UHM4" } ] } ] }, { "uniprot_ac": "A0A8V0X962", "gene_name": "RAB31", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0X962", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X962" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0X962", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X962" } ] } ] }, { "uniprot_ac": "A0A8V0XBX5", "gene_name": "RAP2B", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XBX5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XBX5" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0XBX5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XBX5" } ] } ] }, { "uniprot_ac": "A0A8V0XC33", "gene_name": "RAB23", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XC33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XC33" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0XC33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XC33" } ] } ] }, { "uniprot_ac": "A0A8V0XDD5", "gene_name": "RAB12", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XDD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XDD5" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0XDD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XDD5" } ] } ] }, { "uniprot_ac": "A0A8V0XGK7", "gene_name": "RAB6A", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XGK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XGK7" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0XGK7", "database": "UniProtKB", "url": 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"MDPLAPLVLYGFSLIISGKVEAALDLILINSFPLVGNSETSLICITSKWRSRESITIDRDQEDVTNQHREPLEVSEDSKRATAKMVIWKREKASETIGAYYCEGKLKDEVTRIHTMKMPRGASFHPVALTVTANKGEHVNISFIRMAAKEEDAVIYKNGSFIHSVPRHEVPGELEVSYPHVQLQDAGVYSARYIGGNLFTSAYTRLIVRRCEAQKWGPSCSSHCPSCMNNGICHEDTGECICPPGFMGKTCEKACGANTFGKTCEESCKENYGCKNYMFCLPDPYGCSCATGWMGLECDKECKPGYYGSDCKLKCNCHNRGTCDRYKGCVCSYGWHGLQCEKEGSADLSPQIENLLDPVELNSGVEFKPYCIASGMPLPKSEEFKLLKQDGTVLRPSLIVTSNRSEAMFTINRVLPRDTGTWVCSVQTVAGMAEKPFQVTVKVPPVPQYAPRLTNSGHNFLIIDINAELHTGDGPVVSTKLLYKPAKRYQSWMSVEVKGSTKRLDNLEPKTEYQFCVQLSRQGEGGEGHPGPQASFTTAALGLPPPEGLTLLPKSMTSLNLSWHPLTLRTDDDIRVEVERKSVNDNGDESSVITQVPGNMSTLIIKDLEPRQQYMCRVRVNTRSQGEWSNYLYAWTFSDRIPPAPYNIKFFNTTDTSSVISWTTAEGHSISSIIISYKIYGKAEYNHIDIIIKNSTITQYHLKGLEPNTVYQVQINAQNNIGLSNPNTSFELKTLPEMKAPYESKGGKMLLIAILGSAGMTCVTILLAFLIMLQLKRANFQRRMAQAFQNVVREEPAVQFNSGTLTLSRKAKNSPDPTIYPVLEWNDIKFQDVIGEGNFGQVLKARIKKDGLRMDAAIKRMKEYASKDDHRDFAGELEVLCKLGHHPNIINLLGACEHRGYLYLAIEYAPHGNLLDFLRKSRVLETDPAFAIANSTASTLSSQQLLHFAADVARGMDYLSQKQFIHRDLAARNILVGENYVAKIADFGLSRGQEVYVKKTMGRLPVRWMAIESLNYSVYTTNSDVWSYGVLLWEIVSLGGTPYCGMTCAELYEKLPQGYRLEKPLNCDDEVYDLMRQCWREKPYERPSFAQILVSLNRMLEERKTYVNTTLYEKFTYAGIDCSAEEAA", "length": 1128, "header": "tr|A0A3Q2UKD3-1|A0A3Q2UKD3_CHICK Isoform 1 of Angiopoietin-1 receptor OS=Gallus gallus OX=9031 GN=TEK PE=4 SV=1 CANONICAL=A0A3Q2UKD3-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2UKD3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UKD3/entry#A0A3Q2UKD3-1", "sequence": { "sequence": "MDPLAPLVLYGFSLIISGKVEAALDLILINSFPLVGNSETSLICITSKWRSRESITIDRDQEDVTNQHREPLEVSEDSKRATAKMVIWKREKASETIGAYYCEGKLKDEVTRIHTMKMPRGASFHPVALTVTANKGEHVNISFIRMAAKEEDAVIYKNGSFIHSVPRHEVPGELEVSYPHVQLQDAGVYSARYIGGNLFTSAYTRLIVRRCEAQKWGPSCSSHCPSCMNNGICHEDTGECICPPGFMGKTCEKACGANTFGKTCEESCKENYGCKNYMFCLPDPYGCSCATGWMGLECDKECKPGYYGSDCKLKCNCHNRGTCDRYKGCVCSYGWHGLQCEKEGSADLSPQIENLLDPVELNSGVEFKPYCIASGMPLPKSEEFKLLKQDGTVLRPSLIVTSNRSEAMFTINRVLPRDTGTWVCSVQTVAGMAEKPFQVTVKVPPVPQYAPRLTNSGHNFLIIDINAELHTGDGPVVSTKLLYKPAKRYQSWMSVEVKGSTKRLDNLEPKTEYQFCVQLSRQGEGGEGHPGPQASFTTAALGLPPPEGLTLLPKSMTSLNLSWHPLTLRTDDDIRVEVERKSVNDNGDESSVITQVPGNMSTLIIKDLEPRQQYMCRVRVNTRSQGEWSNYLYAWTFSDRIPPAPYNIKFFNTTDTSSVISWTTAEGHSISSIIISYKIYGKAEYNHIDIIIKNSTITQYHLKGLEPNTVYQVQINAQNNIGLSNPNTSFELKTLPEMKAPYESKGGKMLLIAILGSAGMTCVTILLAFLIMLQLKRANFQRRMAQAFQNVVREEPAVQFNSGTLTLSRKAKNSPDPTIYPVLEWNDIKFQDVIGEGNFGQVLKARIKKDGLRMDAAIKRMKEYASKDDHRDFAGELEVLCKLGHHPNIINLLGACEHRGYLYLAIEYAPHGNLLDFLRKSRVLETDPAFAIANSTASTLSSQQLLHFAADVARGMDYLSQKQFIHRDLAARNILVGENYVAKIADFGLSRGQEVYVKKTMGRLPVRWMAIESLNYSVYTTNSDVWSYGVLLWEIVSLGGTPYCGMTCAELYEKLPQGYRLEKPLNCDDEVYDLMRQCWREKPYERPSFAQILVSLNRMLEERKTYVNTTLYEKFTYAGIDCSAEEAA", "length": 1128, "header": "tr|A0A3Q2UKD3-1|A0A3Q2UKD3_CHICK Isoform 1 of Angiopoietin-1 receptor OS=Gallus gallus OX=9031 GN=TEK PE=4 SV=1 CANONICAL=A0A3Q2UKD3-1" }, "locus": { "chromosome": "Z", "start_pos": 69175576, "end_pos": 69140084, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010015548.1", "url": "https://www.ensembl.org/id/ENSGALT00010015548.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010009064.1", "url": "https://www.ensembl.org/id/ENSGALP00010009064.1" } ] } }, { "isoform_ac": "A0A8V0XQV1-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UKD3/entry#A0A8V0XQV1-1", "sequence": { "sequence": "MDPLAPLVLYGFSLIISGKVEAALDLILINSFPLVGNSETSLICITSKWRSRESITIDRDQEDVTNQHREPLEVSEDSKRATAKMVIWKREKASETIGAYYCEGKLKDEVTRIHTMKMPRGASFHPVALTVTANKGEHVNISFIRMAAKEEDAVIYKNGSFIHSVPRHEVPGELEVSYPHVQLQDAGVYSARYIGGNLFTSAYTRLIVRRCEAQKWGPSCSSHCPSCMNNGICHEDTGECICPPGFMGKTCEKACGANTFGKTCEESCKENYGCKNYMFCLPDPYGCSCATGWMGLECDKECKPGYYGSDCKLKCNCHNRGTCDRYKGCVCSYGWHGLQCEKEGSADLSPQIENLLDPVELNSGVEFKPYCIASGMPLPKSEEFKLLKQDGTVLRPSLIVTSNRSEAMFTINRVLPRDTGTWVCSVQTVAGMAEKPFQVTVKVPPVPQYAPRLTNSGHNFLIIDINAELHTGDGPVVSTKLLYKPAKRYQSWMSVEVKGSTKRLDNLEPKTEYQFCVQLSRQGEGGEGHPGPQASFTTAALGLPPPEGLTLLPKSMTSLNLSWHPLTLRTDDDIRVEVERKSVNDNGDESSVITQVPGNMSTLIIKDLEPRQQYMCRVRVNTRSQGEWSNYLYAWTFSDRIPPAPYNIKFFNTTDTSSVISWTTAEGHSISSIIISYKIYGKAEYNHIDIIIKNSTITQYHLKGLEPNTVYQVQINAQNNIGLSNPNTSFELKTLPEMKAPYESKGGKMLLIAILGSAGMTCVTILLAFLIMLQLKRANFQRRMAQAFQNVVREEPAVQFNSGTLTLSRKAKNSPDPTIYPVLEWNDIKFQDVIGEGNFGQVLKARIKKDGLRMDAAIKRMKEYASKDDHRDFAGELEVLCKLGHHPNIINLLGACEHRGYLYLAIEYAPHGNLLDFLRKSRVLETDPAFAIANSTASTLSSQQLLHFAADVARGMDYLSQKQFIHRDLAARNILVGENYVAKIADFGLSRGQEVYVKKTMGRLPVRWMAIESLNYSVYTTNSDVWNAVLWNDLCRTL", "length": 1038, "header": "tr|A0A8V0XQV1-1|A0A3Q2UKD3_CHICK Computationally mapped isoform of Angiopoietin-1 receptor OS=Gallus gallus OX=9031 GN=TEK PE=4 SV=1 CANONICAL=A0A3Q2UKD3-1" }, "locus": { "chromosome": "Z", "start_pos": 69174989, "end_pos": 69140084, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010015547.1", "url": "https://www.ensembl.org/id/ENSGALT00010015547.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010009063.1", "url": "https://www.ensembl.org/id/ENSGALP00010009063.1" } ] } }, { "isoform_ac": "A0A8V0XSW6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UKD3/entry#A0A8V0XSW6-1", "sequence": { "sequence": "MDSSGKVEAALDLILINSFPLVGNSETSLICITSKWRSRESITIDRDQEDVTNQHREPLEVSEDSKRATAKMVIWKREKASETIGAYYCEGKLKDEVTRIHTMKMPRGASFHPVALTVTANKGEHVNISFIRMAAKEEDAVIYKNGSFIHSVPRHEVPGELEVSYPHVQLQDAGVYSARYIGGNLFTSAYTRLIVRRCEAQKWGPSCSSHCPSCMNNGICHEDTGECICPPGFMGKTCEKACGANTFGKTCEESCKENYGCKNYMFCLPDPYGCSCATGWMGLECDKECKPGYYGSDCKLKCNCHNRGTCDRYKGCVCSYGWHGLQCEKEGSADLSPQIENLLDPVELNSGVEFKPYCIASGMPLPKSEEFKLLKQDGTVLRPSLIVTSNRSEAMFTINRVLPRDTGTWVCSVQTVAGMAEKPFQVTVKVPPVPQYAPRLTNSGHNFLIIDINAELHTGDGPVVSTKLLYKPAKRYQSWMSVEVKGSTKRLDNLEPKTEYQFCVQLSRQGEGGEGHPGPQASFTTAALGLPPPEGLTLLPKSMTSLNLSWHPLTLRTDDDIRVEVERKSVNDNGDESSVITQVPGNMSTLIIKDLEPRQQYMCRVRVNTRSQGEWSNYLYAWTFSDRIPPAPYNIKFFNTTDTSSVISWTTAEGHSISSIIISYKIYGKAEYNHIDIIIKNSTITQYHLKGLEPNTVYQVQINAQNNIGLSNPNTSFELKTLPEMKAPYESKGGKMLLIAILGSAGMTCVTILLAFLIMLQLKRANFQRRMAQAFQNVVREEPAVQFNSGTLTLSRKAKNSPDPTIYPVLEWNDIKFQDVIGEGNFGQVLKARIKKDGLRMDAAIKRMKEYASKDDHRDFAGELEVLCKLGHHPNIINLLGACEHRGYLYLAIEYAPHGNLLDFLRKSRVLETDPAFAIANSTASTLSSQQLLHFAADVARGMDYLSQKQFIHRDLAARNILVGENYVAKIADFGLSRGQEVYVKKTMGRLPVRWMAIESLNYSVYTTNSDVWSYGVLLWEIVSLGGTPYCGMTCAELYEKLPQGYRLEKPLNCDDEVYDLMRQCWREKPYERPSFAQILVSLNRMLEERKTYVNTTLYEKFTYAGIDCSAEEAA", "length": 1115, "header": "tr|A0A8V0XSW6-1|A0A3Q2UKD3_CHICK Computationally mapped isoform of Angiopoietin-1 receptor OS=Gallus gallus OX=9031 GN=TEK PE=4 SV=1 CANONICAL=A0A3Q2UKD3-1" }, "locus": { "chromosome": "Z", "start_pos": 69175576, "end_pos": 69142189, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010015544.1", "url": "https://www.ensembl.org/id/ENSGALT00010015544.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010009061.1", "url": "https://www.ensembl.org/id/ENSGALP00010009061.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:427368", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427368", "resource": "KEGG Pathway" }, { "id": "R-GGA-210993", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-210993", "resource": "Reactome", "description": "Tie2 Signaling" }, { "id": "R-GGA-5673001", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5673001", "resource": "Reactome", "description": "RAF/MAP kinase cascade" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I5ZW61-1", "protein_name": "Angiopoietin-1 receptor", "gene_name": "Tek", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLMTVMHHALSFFLGLVEGAMDLILINSLPLVSDAETSLTCIASGWHPHEPITIGRDFEALMNQHQDPLEVTQDVTREWAKKVVWKREKASKINGAYFCEGRVRGQAIRIRTMKMRQQASFLPATLTMTVDRGDNVNISFKKVLIKEEDAVIYKNGSFIHSVPRHEVPDILEVHLPHAQPQDAGVYSARYIGGNLFTSAFTRLIVRRCEAQKWGPDCNRPCTTCKNNGVCHEDTGECICPPGFMGRTCEKACEPHTFGRTCKERCSGSEGCKSYVFCLPDPYGCSCATGWRGLQCNEACPYGHYGPDCKLRCHCTNEEMCDRFQGCLCSQGWQGLQCEKEGRPRMTPQIEDLPDHIEVNSGKFNPICKASGWPLPTSEEMTLVKPDGTVLQPNDFNHTDHFSVAIFTVNRILPPDSGVWVCSVNTVAGMVEKPFNISVKVLPEPLHAPNVIDTGHNFAIINISSEPYFGDGPIKSKKLFYKPVNQAWKYIQVMNEIVTLNYLEPRTDYELCVQLVRPGEGGEGHPGPVRRFTTASIGLPPPRGLSLLPKSQTALNLTWQPIFTSSEDEFYVEVERWSQQTRSDQQNIKVPGNLTSVLLNNLLPREQYSVRARVNTKAQGEWSEELRAWTLSDILPPQPENIKITNITDYTALVSWTIVDGYSISSIIIRYKVQGKNEDQHIDVKIKNATITQYQLKGLEPETTYHVDIFAENNIGSSNPAFSQEIRTLPAPKDLGGGKMLLIAILGSAGMTCITVLLAFLIMLQLKRANVQRRMAQAFQNVREEPAVQFNSGTLALNRKAKNNPDPTIYPVLDWNDIKFQDVIGEGNFGQVLKARIKKDGLRMDAAIKRMKEYASKDDHRDFAGELEVLCKLGHHPNIINLLGACEHRGYLYLAIEYAPHGNLLDFLRKSRVLETDPAFAIANSTASTLSSQQLLHFAADVARGMDYLSQKQFIHRDLAARNILVGENYIAKIADFGLSRGQEVYVKKTMGRLPVRWMAIESLNYSVYTTNSDETLPSVSVGLTDSTSCVPGGTPYCGMTCAELYEKLPQGYRLEKPLNCDDEVYDLMRQCWREKPYERPSFAQILVSLNRMLEERKTYVNTTLYEKFTYAGIDCSAEEAA", "length": 1121 }, "evidence": [ { "id": "A0A3Q2UKD3", "url": "https://omabrowser.org/oma/group/A0A3Q2UKD3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q02763-1", "protein_name": "Angiopoietin-1 receptor", "gene_name": "TEK", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDSLASLVLCGVSLLLSGTVEGAMDLILINSLPLVSDAETSLTCIASGWRPHEPITIGRDFEALMNQHQDPLEVTQDVTREWAKKVVWKREKASKINGAYFCEGRVRGEAIRIRTMKMRQQASFLPATLTMTVDKGDNVNISFKKVLIKEEDAVIYKNGSFIHSVPRHEVPDILEVHLPHAQPQDAGVYSARYIGGNLFTSAFTRLIVRRCEAQKWGPECNHLCTACMNNGVCHEDTGECICPPGFMGRTCEKACELHTFGRTCKERCSGQEGCKSYVFCLPDPYGCSCATGWKGLQCNEACHPGFYGPDCKLRCSCNNGEMCDRFQGCLCSPGWQGLQCEREGIQRMTPKIVDLPDHIEVNSGKFNPICKASGWPLPTNEEMTLVKPDGTVLHPKDFNHTDHFSVAIFTIHRILPPDSGVWVCSVNTVAGMVEKPFNISVKVLPKPLNAPNVIDTGHNFAVINISSEPYFGDGPIKSKKLLYKPVNHYEAWQHIQVTNEIVTLNYLEPRTEYELCVQLVRRGEGGEGHPGPVRRFTTASIGLPPPRGLNLLPKSQTTLNLTWQPIFPSSEDDFYVEVERRSVQKSDQQNIKVPGNLTSVLLNNLHPREQYVVRARVNTKAQGEWSEDLTAWTLSDILPPQPENIKISNITHSSAVISWTILDGYSISSITIRYKVQGKNEDQHVDVKIKNATITQYQLKGLEPETAYQVDIFAENNIGSSNPAFSHELVTLPESQAPADLGGGKMLLIAILGSAGMTCLTVLLAFLIILQLKRANVQRRMAQAFQNVREEPAVQFNSGTLALNRKVKNNPDPTIYPVLDWNDIKFQDVIGEGNFGQVLKARIKKDGLRMDAAIKRMKEYASKDDHRDFAGELEVLCKLGHHPNIINLLGACEHRGYLYLAIEYAPHGNLLDFLRKSRVLETDPAFAIANSTASTLSSQQLLHFAADVARGMDYLSQKQFIHRDLAARNILVGENYVAKIADFGLSRGQEVYVKKTMGRLPVRWMAIESLNYSVYTTNSDVWSYGVLLWEIVSLGGTPYCGMTCAELYEKLPQGYRLEKPLNCDDEVYDLMRQCWREKPYERPSFAQILVSLNRMLEERKTYVNTTLYEKFTYAGIDCSAEEAA", "length": 1124 }, "evidence": [ { "id": "A0A3Q2UKD3", "url": "https://omabrowser.org/oma/group/A0A3Q2UKD3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q02858-1", "protein_name": "Angiopoietin-1 receptor", "gene_name": "Tek", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDSLAGLVLCGVSLLLYGVVEGAMDLILINSLPLVSDAETSLTCIASGWHPHEPITIGRDFEALMNQHQDPLEVTQDVTREWAKKVVWKREKASKINGAYFCEGRVRGQAIRIRTMKMRQQASFLPATLTMTVDRGDNVNISFKKVLIKEEDAVIYKNGSFIHSVPRHEVPDILEVHLPHAQPQDAGVYSARYIGGNLFTSAFTRLIVRRCEAQKWGPDCSRPCTTCKNNGVCHEDTGECICPPGFMGRTCEKACEPHTFGRTCKERCSGPEGCKSYVFCLPDPYGCSCATGWRGLQCNEACPSGYYGPDCKLRCHCTNEEICDRFQGCLCSQGWQGLQCEKEGRPRMTPQIEDLPDHIEVNSGKFNPICKASGWPLPTSEEMTLVKPDGTVLQPNDFNYTDRFSVAIFTVNRVLPPDSGVWVCSVNTVAGMVEKPFNISVKVLPEPLHAPNVIDTGHNFAIINISSEPYFGDGPIKSKKLFYKPVNQAWKYIEVTNEIFTLNYLEPRTDYELCVQLARPGEGGEGHPGPVRRFTTASIGLPPPRGLSLLPKSQTALNLTWQPIFTNSEDEFYVEVERRSLQTTSDQQNIKVPGNLTSVLLSNLVPREQYTVRARVNTKAQGEWSEELRAWTLSDILPPQPENIKISNITDSTAMVSWTIVDGYSISSIIIRYKVQGKNEDQHIDVKIKNATVTQYQLKGLEPETTYHVDIFAENNIGSSNPAFSHELRTLPHSPASADLGGGKMLLIAILGSAGMTCITVLLAFLIMLQLKRANVQRRMAQAFQNREEPAVQFNSGTLALNRKAKNNPDPTIYPVLDWNDIKFQDVIGEGNFGQVLKARIKKDGLRMDAAIKRMKEYASKDDHRDFAGELEVLCKLGHHPNIINLLGACEHRGYLYLAIEYAPHGNLLDFLRKSRVLETDPAFAIANSTASTLSSQQLLHFAADVARGMDYLSQKQFIHRDLAARNILVGENYIAKIADFGLSRGQEVYVKKTMGRLPVRWMAIESLNYSVYTTNSDVWSYGVLLWEIVSLGGTPYCGMTCAELYEKLPQGYRLEKPLNCDDEVYDLMRQCWREKPYERPSFAQILVSLNRMLEERKTYVNTTLYEKFTYAGIDCSAEEAA", "length": 1122 }, "evidence": [ { "id": "A0A3Q2UKD3", "url": "https://omabrowser.org/oma/group/A0A3Q2UKD3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q06807-1", "protein_name": "Angiopoietin-1 receptor", "gene_name": "TEK", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MDSLAGLVLCGVSLLLSATVDGAMDLILINSLPLVSDAETSLTCIASGWRPHEPITIGRDFEALMNQHQDPLEVTQDATREWAKKVVWKREKASKINGAYFCEGRVRGQAIRIRTMKMRQQASFLPATLTMTVDRGDNVNISFKKVLIKEEDAVIYKNGSFIHSVPRHEVPDILEVQVPHAQPQDAGVYSARYIGGNLFTSAFTRLIVRRCEAQKWGPECNRICTACMNNGICHEDTGECICPPGFMGRTCEKACEPHTFGRTCKERCSEPEGCKSFVFCLPDPYGCSCATGWKGLQCNEACQPGYYGPDCKLRCSCTNGEKCDRFQGCLCSPGRQGLQCEKEGVPRMTPKIEDLPDHIEVNSGKFNPICKASGWPRPANEEMTLVKPDGTVLRPKDFNHTGHLSVATFTINRILPPDSGVWVCSVNTVSGMVEKPFNISVKVLPKPLNAPKVIDTGHNFAVINISSEPYFGDGPIKSKKLLYKPVNHYEAWRHIQVTNEIVTLNYLEPRTEYELCVQLVRRGEGGEGHPGPVRRFTTASIGLPPPRGLSLLPKSQTTLNLTWQPIFPSSEDDFYVEVERRSVQMNSDQQNIKVPGNLTSVLLNNLHPREQYIVRARVNTKAQGEWSEDLIAWTLSDIVPPQPENIKIFNITDSSAVISWTILDGYSISAIIIRYKVQGKNEDQHIDVKIKNATITQYQLKGLEPQTVYQVDIFAENNIGSSNPTSSHELTTLSESQAPADLGGRKMLLIAILGSAGMTCLTVLLAFLIMLQLKRANVQRRMAQAFQNVREEPAVQFNSGTLALNRKAKNNPDPTIYPVLDWNDIKFQDVIGEGNFGQVLKARIKKDGLRMDAAIKRMKEYASKDDHRDFAGELEVLCKLGHHPNIINLLGACEHRGYLYLAIEYAPHGNLLDFLRKSRVLETDPAFAIANSTASTLSSQQLLHFAADVARGMDYLSQKQFIHRDLAARNILVGENYVAKIADFGLSRGQEVYVKKTMGRLPVRWMAIESLNYSVYTTNSDVWSYGVLLWEIVSLGGTPYCGMTCAELYEKLPQGYRLEKPLNCDDEVYDLMRQCWREKPYERPSFAQILVSLNRMLEERKTYVNTTLYEKFTYAGIDCSAEEAA", "length": 1125 }, "evidence": [ { "id": "A0A3Q2UKD3", "url": "https://omabrowser.org/oma/group/A0A3Q2UKD3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 28, "go_terms": [ { "name": "regulation of establishment or maintenance of cell polarity", "id": "GO:0032878", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032878", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UKD3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UKD3" } ], "pmid": "" }, { "name": "angiogenesis", "id": "GO:0001525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001525", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UKD3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UKD3" } ], "pmid": "" }, { "name": "cell surface receptor protein tyrosine kinase signaling pathway", "id": "GO:0007169", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007169", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UKD3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UKD3" } ], "pmid": "" }, { "name": "negative regulation of apoptotic process", "id": "GO:0043066", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043066", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UKD3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UKD3" } ], "pmid": "" }, { "name": "positive regulation of MAPK cascade", "id": "GO:0043410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043410", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UKD3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UKD3" } ], "pmid": "" }, { "name": "positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction", "id": "GO:0051897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051897", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UKD3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UKD3" } ], "pmid": "" }, { "name": "positive regulation of ERK1 and ERK2 cascade", "id": "GO:0070374", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070374", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UKD3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UKD3" } ], "pmid": "" }, { "name": "positive regulation of endothelial cell migration", "id": "GO:0010595", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010595", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UKD3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UKD3" } ], "pmid": "" }, { "name": "positive regulation of angiogenesis", "id": "GO:0045766", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045766", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UKD3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UKD3" } ], "pmid": "" }, { "name": "regulation of endothelial cell proliferation", "id": "GO:0001936", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001936", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UKD3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UKD3" } ], "pmid": "" }, { "name": "substrate adhesion-dependent cell spreading", "id": "GO:0034446", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034446", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UKD3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UKD3" } ], "pmid": "" }, { "name": "positive regulation of focal adhesion assembly", "id": "GO:0051894", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051894", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UKD3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UKD3" } ], "pmid": "" }, { "name": "negative regulation of angiogenesis", "id": "GO:0016525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016525", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UKD3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UKD3" } ], "pmid": "" }, { "name": "hemopoiesis", "id": "GO:0030097", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030097", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UKD3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UKD3" } ], "pmid": "" }, { "name": "positive regulation of Rho protein signal transduction", "id": "GO:0035025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035025", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UKD3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UKD3" } ], "pmid": "" }, { "name": "cellular response to mechanical stimulus", "id": "GO:0071260", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071260", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UKD3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UKD3" } ], "pmid": "" }, { "name": "sprouting angiogenesis", "id": "GO:0002040", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002040", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UKD3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UKD3" } ], "pmid": "" }, { "name": "positive regulation of Rac protein signal transduction", "id": "GO:0035022", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035022", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UKD3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UKD3" } ], "pmid": "" }, { "name": "endothelial cell proliferation", "id": "GO:0001935", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001935", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UKD3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UKD3" } ], "pmid": "" }, { "name": "Tie signaling pathway", "id": "GO:0048014", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048014", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UKD3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UKD3" } ], "pmid": "" }, { "name": "regulation of endothelial cell apoptotic process", "id": "GO:2000351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000351", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UKD3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UKD3" } ], "pmid": "" }, { "name": "positive regulation of cell adhesion", "id": "GO:0045785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045785", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UKD3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UKD3" } ], "pmid": "" }, { "name": "regulation of cell migration", "id": "GO:0030334", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030334", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UKD3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UKD3" } ], "pmid": "" }, { "name": "regulation of intracellular signal transduction", "id": "GO:1902531", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902531", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UKD3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UKD3" } ], "pmid": "" }, { "name": "regulation of angiogenesis", "id": "GO:0045765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045765", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UKD3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UKD3" } ], "pmid": "" }, { "name": "positive regulation of signal transduction", "id": "GO:0009967", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009967", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UKD3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UKD3" } ], "pmid": "" }, { "name": "cell-substrate adhesion", "id": "GO:0031589", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031589", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UKD3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UKD3" } ], "pmid": "" }, { "name": "positive regulation of multicellular organismal process", "id": "GO:0051240", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051240", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UKD3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UKD3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UKD3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UKD3" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UKD3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UKD3" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UKD3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UKD3" } ], "pmid": "" }, { "name": "transmembrane receptor protein tyrosine kinase activity", "id": "GO:0004714", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004714", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UKD3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UKD3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 13, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UKD3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UKD3" } ], "pmid": "" }, { "name": "actin filament", "id": "GO:0005884", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005884", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UKD3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UKD3" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UKD3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UKD3" } ], "pmid": "" }, { "name": "cell-cell junction", "id": "GO:0005911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005911", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UKD3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UKD3" } ], "pmid": "" }, { "name": "focal adhesion", "id": "GO:0005925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005925", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UKD3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UKD3" } ], "pmid": "" }, { "name": "cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UKD3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UKD3" } ], "pmid": "" }, { "name": "basolateral plasma membrane", "id": "GO:0016323", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016323", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UKD3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UKD3" } ], "pmid": "" }, { "name": "receptor complex", "id": "GO:0043235", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043235", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UKD3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UKD3" } ], "pmid": "" }, { "name": "membrane raft", "id": "GO:0045121", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045121", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UKD3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UKD3" } ], "pmid": "" }, { "name": "apical plasma membrane", "id": "GO:0016324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016324", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UKD3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UKD3" } ], "pmid": "" }, { "name": "stress fiber", "id": "GO:0001725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001725", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UKD3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UKD3" } ], "pmid": "" }, { "name": "microvillus", "id": "GO:0005902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005902", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UKD3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UKD3" } ], "pmid": "" }, { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UKD3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UKD3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1015, "end_pos": 1017, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1108, "end_pos": 1110, "annotation": "n_glycosylation_sequon" }, { "start_pos": 140, "end_pos": 142, "annotation": "n_glycosylation_sequon" }, { "start_pos": 158, "end_pos": 160, "annotation": "n_glycosylation_sequon" }, { "start_pos": 403, "end_pos": 405, "annotation": "n_glycosylation_sequon" }, { "start_pos": 560, "end_pos": 562, "annotation": "n_glycosylation_sequon" }, { "start_pos": 599, "end_pos": 601, "annotation": "n_glycosylation_sequon" }, { "start_pos": 652, "end_pos": 654, "annotation": "n_glycosylation_sequon" }, { "start_pos": 694, "end_pos": 696, "annotation": "n_glycosylation_sequon" }, { "start_pos": 727, "end_pos": 729, "annotation": "n_glycosylation_sequon" }, { "start_pos": 934, "end_pos": 936, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "10596", "name": "", "equation": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V1ADF0-1", "F1N9Y5-1", "A0A8V0XQG0-1", "A0A8V0Y9A0-1", "A0A8V1AFM7-1", "A0A8V0Z0R8-1", "A0A8V0Z4B2-1", "A0A8V0ZBN6-1", "P09324-1", "A0A8V0XHW1-1", "A0A8V0YW12-1", "A0A8V0YUJ4-1", "A0A8V0ZSN8-1", "F1NVF2-1", "A0A8V1AKW4-1", "A0A8V0XB17-1", "A0A8V0ZC34-1", "A0A8V0YYC1-1", "A0A8V0ZND5-1", "A0A8V1ACF7-1", "A0A8V0ZP30-1", "E1BTE1-1", "Q07497-1", "A0A8V0X6E7-1", "F1NCL8-1", "A0A8V0XNF4-1", "A0A8V0XN86-1", "A0A8V0YEV0-1", "A0A8V0XQ80-1", "A0A8V0XZ82-1", "A0A8V0YZE5-1", "A0A8V0YYZ7-1", "A0A8V0YCV8-1", "A0A8V0YGR1-1", "A0A8V0YNY4-1", "A0A8V0YXM5-1", "A0A8V0YXZ9-1", "A0A3Q2UKD3-1", "A0A8V0YIT6-1", "A0A8V0YIV6-1", "R4GJW5-1", "A0A8V1A3N1-1", "A0A8V1A9R2-1", "A0A8V0ZE65-1", "A0A8V0ZER1-1", "A0A8V0ZXS7-1", "A0A8V1A7N1-1", "H9KZZ1-1", "F1NQL9-1", "A0A8V1ABP4-1", "F1NZY8-1", "Q02977-1", "A0A1D5PD64-1", "A0A8V0ZDU6-1", "A0A3Q2U1T2-1", "R4GJB8-1", "A0A3Q2U639-1", "A0A8V0X5W9-1", "E1C7Z1-1", "A0A8V0Y7Y3-1", "Q5ZIU3-1", "A0A8V0YPR4-1", "A0A8V0YT43-1", "A0A8V0Z3S3-1", "A0A8V0YJJ1-1", "A0A8V0YKP8-1", "A0A8V0YZ74-1", "A0A8V0ZWV8-1", "A0A8V1A069-1", "A0A8V1A7E0-1", "A0A8V1AEL3-1", "E1BTT3-1", "F1N996-1", "H9KZZ2-1", "E1C2C8-1", "Q05876-1", "Q90891-1", "O42422-1", "P00523-1", "P08941-1", "P13387-1", "P18460-1", "P18461-1", "P21804-1", "P28693-1", "P29318-1", "P42683-1", "P54755-1", "Q00944-1", "Q07494-1", "Q07496-1", "Q07498-1", "Q08156-1", "Q6XUX0-1", "Q75R65-1", "Q8AXY6-1", "Q8JH64-1", "Q8QHL3-1", "Q91009-1", "Q91044-1", "Q91987-1", "Q98949-1", "Q9PUF6-1", "F1NW21-1", "A0A8V0YLC3-1", "A0A8V0Z7L6-1", "F1NJX6-1", "A0A8V0YUC4-1", "F1NUX4-1", "A0A8V1A2E6-1", "E1BX69-1", "A0A8V0XPF0-1", "A0A8V0XFC9-1", "A0A8V0XBZ6-1", "A0A8V0ZRU7-1", "A0A8V0ZXD3-1", "A0A8V0YYI3-1", "A0A8V0YWW2-1", "A0A8V0YZP9-1", "A0A8V0YRJ8-1", "F1NLR7-1", "A0A8V0XCY6-1", "A0A8V1AMK9-1", "A0A8V0Z189-1", "P41239-1" ], "evidence": [ { "id": "10596", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/10596" } ] }, { "id": "R-GGA-204773", "name": "Interaction of Tie2 and Grb7", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q2UKD3-1" ], "evidence": [ { "id": "R-GGA-204773", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-204773" } ] }, { "id": "R-GGA-204779", "name": "Interaction of Tie2 with Ang1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q2UKD3-1" ], "evidence": [ { "id": "R-GGA-204779", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-204779" } ] }, { "id": "R-GGA-204798", "name": "Interaction of Tie2 and p85 of PI3K", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q2UKD3-1" ], "evidence": [ { "id": "R-GGA-204798", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-204798" } ] }, { "id": "R-GGA-204813", "name": "Interaction of Tie2 and Grb14", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q2UKD3-1" ], "evidence": [ { "id": "R-GGA-204813", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-204813" } ] }, { "id": "R-GGA-204824", "name": "Interaction of Tie2 and Ang4", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q2UKD3-1" ], "evidence": [ { "id": "R-GGA-204824", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-204824" } ] }, { "id": "R-GGA-204850", "name": "Interaction of Tie2 and Dok-2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q2UKD3-1" ], "evidence": [ { "id": "R-GGA-204850", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-204850" } ] }, { "id": "R-GGA-204861", "name": "Interaction of Tie2 and Shc1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q2UKD3-1" ], "evidence": [ { "id": "R-GGA-204861", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-204861" } ] }, { "id": "R-GGA-204863", "name": "Interaction of Tie2 with Ang2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q2UKD3-1" ], "evidence": [ { "id": "R-GGA-204863", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-204863" } ] }, { "id": "R-GGA-204871", "name": "Interaction of Tie2 and Grb2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q2UKD3-1" ], "evidence": [ { "id": "R-GGA-204871", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-204871" } ] }, { "id": "R-GGA-204873", "name": "Interaction of Tie2 and Shp2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q90687-1", "A0A3Q2UKD3-1" ], "evidence": [ { "id": "R-GGA-204873", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-204873" } ] }, { "id": "R-GGA-210881", "name": "Dimerization of Tie2/Ang1 complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q2UKD3-1" ], "evidence": [ { "id": "R-GGA-210881", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-210881" } ] }, { "id": "R-GGA-210974", "name": "Interaction of SOS-1 to Tie2 bound Grb2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q2UKD3-1" ], "evidence": [ { "id": "R-GGA-210974", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-210974" } ] }, { "id": "R-GGA-210977", "name": "Sos-mediated nucleotide exchange of Ras (Tie2 receptor:Grb2:Sos)", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q5F352-1", "A0A3Q2UKD3-1", "P08642-1" ], "evidence": [ { "id": "R-GGA-210977", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-210977" } ] }, { "id": "R-GGA-5672965", "name": "RAS GEFs promote RAS nucleotide exchange", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XB58-1", "F1P011-1", "A0M8T9-1", "A0A8V0XB17-1", "A0A8V0YLC3-1", "A0A8V0YWD3-1", "A0A8V0Z7L6-1", "F1NCL8-1", "Q5F352-1", "A0A8V0XNF4-1", "A0A8V0XQ80-1", "A0A8V0YGR1-1", "A0A8V0YNY4-1", "A0A8V0YYZ7-1", "A0A8V0ZXS7-1", "A0A8V1A7N1-1", "A0A8V0YZE5-1", "A0A8V0ZB33-1", "A0A3Q2U639-1", "A0A3Q2UKD3-1", "P08642-1", "Q08156-1", "A0A8V0YIT6-1" ], "evidence": [ { "id": "R-GGA-5672965", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5672965" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5PD64", "gene_name": "MAP2K3", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PD64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PD64" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A1D5PD64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PD64" } ] } ] }, { "uniprot_ac": "A0A3Q2U1T2", "gene_name": "BLK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2U1T2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U1T2" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A3Q2U1T2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U1T2" } ] } ] }, { "uniprot_ac": "A0A3Q2U639", "gene_name": "FYN", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2U639", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U639" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A3Q2U639", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U639" } ] } ] }, { "uniprot_ac": "A0A3Q2UKD3", "gene_name": "TEK", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2UKD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UKD3" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A3Q2UKD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UKD3" } ] } ] }, { "uniprot_ac": "A0A8V0X5W9", "gene_name": "TYK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X5W9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X5W9" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0X5W9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X5W9" } ] } ] }, { "uniprot_ac": "A0A8V0X6E7", "gene_name": "FES", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X6E7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X6E7" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0X6E7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X6E7" } ] } ] }, { "uniprot_ac": "A0A8V0XB17", "gene_name": "FGFR2", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XB17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XB17" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0XB17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XB17" } ] } ] }, { "uniprot_ac": "A0A8V0XB58", "gene_name": "CAMK2D", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XB58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XB58" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V0XB58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XB58" } ] } ] }, { "uniprot_ac": "A0A8V0XBZ6", "gene_name": "EPHA7", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XBZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XBZ6" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0XBZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XBZ6" } ] } ] }, { "uniprot_ac": "A0A8V0XCY6", "gene_name": "TTK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XCY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCY6" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V0XCY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCY6" } ] } ] }, { "uniprot_ac": "A0A8V0XFC9", "gene_name": "EPHA5", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XFC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFC9" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0XFC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFC9" } ] } ] }, { "uniprot_ac": "A0A8V0XHW1", "gene_name": "LYN", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XHW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XHW1" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0XHW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XHW1" } ] } ] }, { "uniprot_ac": "A0A8V0XN86", "gene_name": "MUSK", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XN86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XN86" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0XN86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XN86" } ] } ] }, { "uniprot_ac": "A0A8V0XNF4", "gene_name": "EGFR", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XNF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNF4" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0XNF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNF4" } ] } ] }, { "uniprot_ac": "A0A8V0XPF0", "gene_name": "EPHA6", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XPF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XPF0" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0XPF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XPF0" } ] } ] }, { "uniprot_ac": "A0A8V0XQ80", "gene_name": "FLT3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQ80", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ80" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0XQ80", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ80" } ] } ] }, { "uniprot_ac": "A0A8V0XQG0", "gene_name": "FLT1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQG0" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0XQG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQG0" } ] } ] }, { "uniprot_ac": "A0A8V0XZ82", "gene_name": "PTK2B", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XZ82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XZ82" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0XZ82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XZ82" } ] } ] }, { "uniprot_ac": "A0A8V0Y7Y3", "gene_name": "ABL2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y7Y3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7Y3" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0Y7Y3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7Y3" } ] } ] }, { "uniprot_ac": "A0A8V0Y9A0", "gene_name": "PTK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y9A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9A0" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0Y9A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9A0" } ] } ] }, { "uniprot_ac": "A0A8V0YCV8", "gene_name": "NTRK2", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YCV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCV8" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0YCV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCV8" } ] } ] }, { "uniprot_ac": "A0A8V0YEV0", "gene_name": "WEE2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YEV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEV0" } ] }, { 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+ ADP + H(+).", "evidence": [ { "id": "A0A8V0YT43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YT43" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0YT43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YT43" } ] } ] }, { "uniprot_ac": "A0A8V0YUC4", "gene_name": "EPHB3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YUC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUC4" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0YUC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUC4" } ] } ] }, { "uniprot_ac": "A0A8V0YUJ4", "gene_name": "BTK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YUJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUJ4" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0YUJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUJ4" } ] } ] }, { "uniprot_ac": "A0A8V0YW12", "gene_name": "FRK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YW12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YW12" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0YW12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YW12" } ] } ] }, { "uniprot_ac": "A0A8V0YWD3", "gene_name": "PTPRA", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0YWD3", "database": "UniProtKB", "url": 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"ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0YXM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXM5" } ] } ] }, { "uniprot_ac": "A0A8V0YXZ9", "gene_name": "FLT4", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YXZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXZ9" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0YXZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXZ9" } ] } ] }, { "uniprot_ac": "A0A8V0YYC1", "gene_name": "TXK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YYC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYC1" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { 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"ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0ZND5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZND5" } ] } ] }, { "uniprot_ac": "A0A8V0ZP30", "gene_name": "LTK", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZP30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP30" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0ZP30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP30" } ] } ] }, { "uniprot_ac": "A0A8V0ZRU7", "gene_name": "EPHB6", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZRU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRU7" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0ZRU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRU7" } ] } ] }, { "uniprot_ac": "A0A8V0ZSN8", "gene_name": "JAK1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZSN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSN8" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0ZSN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSN8" } ] } ] }, { "uniprot_ac": "A0A8V0ZWV8", "gene_name": "TIE1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZWV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWV8" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0ZWV8", "database": "UniProtKB", "url": 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{ "uniprot_ac": "A0A8V1A069", "gene_name": "TESK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A069", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A069" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1A069", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A069" } ] } ] }, { "uniprot_ac": "A0A8V1A2E6", "gene_name": "EPHB1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A2E6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2E6" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V1A2E6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2E6" } ] } ] }, { "uniprot_ac": "A0A8V1A3N1", "gene_name": "MST1R", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A3N1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3N1" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V1A3N1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3N1" } ] } ] }, { "uniprot_ac": "A0A8V1A7E0", "gene_name": "DYRK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1A7E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E0" } ] } ] }, { "uniprot_ac": "A0A8V1A7N1", "gene_name": "ERBB3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7N1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7N1" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V1A7N1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7N1" } ] } ] }, { "uniprot_ac": "A0A8V1A9R2", "gene_name": "JAK3", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A9R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9R2" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V1A9R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9R2" } ] } ] }, { "uniprot_ac": "A0A8V1ABP4", "gene_name": "DSTYK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP4" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1ABP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP4" } ] } ] }, { "uniprot_ac": "A0A8V1ACF7", "gene_name": "ABL1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF7" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V1ACF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF7" } ] } ] }, { "uniprot_ac": "A0A8V1ADF0", "gene_name": "MAP2K2", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF0" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V1ADF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF0" } ] } ] }, { "uniprot_ac": "A0A8V1AEL3", "gene_name": "ZAP70", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AEL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEL3" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V1AEL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEL3" } ] } ] }, { "uniprot_ac": "A0A8V1AFM7", "gene_name": "INSR", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AFM7", "database": "UniProtKB", "url": 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"ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V1AMK9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK9" } ] } ] }, { "uniprot_ac": "A0M8T9", "gene_name": "MET", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0M8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0M8T9" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0M8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0M8T9" } ] } ] }, { "uniprot_ac": "E1BTE1", "gene_name": "WEE2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BTE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BTE1" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "E1BTE1", "database": 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"gene_name": "MATK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C2C8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2C8" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "E1C2C8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2C8" } ] } ] }, { "uniprot_ac": "E1C7Z1", "gene_name": "FER", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C7Z1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C7Z1" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "E1C7Z1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C7Z1" } ] } ] }, { "uniprot_ac": "F1N996", "gene_name": "PTK6", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N996", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N996" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F1N996", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N996" } ] } ] }, { "uniprot_ac": "F1N9Y5", "gene_name": "SYK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N9Y5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N9Y5" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F1N9Y5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N9Y5" } ] } ] }, { "uniprot_ac": "F1NCL8", "gene_name": "FGFR4", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NCL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCL8" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1NCL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCL8" } ] } ] }, { "uniprot_ac": "F1NJX6", "gene_name": "EPHA3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NJX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJX6" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1NJX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJX6" } ] } ] }, { "uniprot_ac": "F1NLR7", "gene_name": "CLK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NLR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLR7" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "F1NLR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLR7" } ] } ] }, { "uniprot_ac": "F1NQL9", "gene_name": "ROS1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NQL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NQL9" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1NQL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NQL9" } ] } ] }, { "uniprot_ac": "F1NUX4", "gene_name": "MTOR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NUX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NUX4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NUX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NUX4" } ] } ] }, { "uniprot_ac": "F1NVF2", "gene_name": "MAP2K6", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NVF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVF2" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "F1NVF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVF2" } ] } ] }, { "uniprot_ac": "F1NW21", "gene_name": "KDR", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NW21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NW21" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1NW21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NW21" } ] } ] }, { "uniprot_ac": "F1NZY8", "gene_name": "TEC", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NZY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NZY8" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F1NZY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NZY8" } ] } ] }, { "uniprot_ac": "F1P011", "gene_name": "CAMK2A", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1P011", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P011" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F1P011", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P011" } ] } ] }, { "uniprot_ac": "H9KZZ1", "gene_name": "NTRK1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "H9KZZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H9KZZ1" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "H9KZZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H9KZZ1" } ] } ] }, { "uniprot_ac": "H9KZZ2", "gene_name": "INSRR", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "H9KZZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H9KZZ2" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "H9KZZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H9KZZ2" } ] } ] }, { "uniprot_ac": "O42422", "gene_name": "EPHA7", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "O42422", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O42422" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "O42422", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O42422" } ] } ] }, { "uniprot_ac": "P00523", "gene_name": "SRC", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "P00523", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00523" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "P00523", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00523" } ] } ] }, { "uniprot_ac": "P08642", "gene_name": "HRAS", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "P08642", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P08642" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "P08642", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P08642" } ] } ] }, { "uniprot_ac": "P08941", "gene_name": "ROS1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "P08941", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P08941" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "P08941", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P08941" } ] } ] }, { "uniprot_ac": "P09324", "gene_name": "YES1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "P09324", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P09324" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "P09324", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P09324" } ] } ] }, { "uniprot_ac": "P13387", "gene_name": "EGFR", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "P13387", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13387" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "P13387", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13387" } ] } ] }, { "uniprot_ac": "P18460", "gene_name": "FGFR3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "P18460", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18460" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "P18460", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18460" } ] } ] }, { "uniprot_ac": "P18461", "gene_name": "FGFR2", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "P18461", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18461" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "P18461", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18461" } ] } ] }, { "uniprot_ac": "P21804", "gene_name": "FGFR1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "P21804", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21804" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "P21804", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21804" } ] } ] }, { "uniprot_ac": "P28693", "gene_name": "EPHB2", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "P28693", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P28693" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "P28693", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P28693" } ] } ] }, { "uniprot_ac": "P29318", "gene_name": "EPHA3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "P29318", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P29318" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "P29318", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P29318" } ] } ] }, { "uniprot_ac": "P41239", "gene_name": "CSK", "activity": [ { "ec_number": "2.7.10.4", "activity": "ATP + [a protein]-(L-tyrosine) = ADP + [a protein]-(L-tyrosine)-phosphate. The optimal peptide substrate contains the sequence (relative to the phosphorylated tyrosine): Glu-Glu-Asp/Glu-Ile-Tyr-Phe-Phe-Phe-Phe. Physiological substrates are C-terminal tail of Src-family protein kinases.", "evidence": [ { "id": "P41239", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P41239" } ] }, { "ec_number": "2.7.10.4", "activity": "", "evidence": [ { "id": "P41239", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P41239" } ] } ] }, { "uniprot_ac": "P42683", "gene_name": "LCK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "P42683", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P42683" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "P42683", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P42683" } ] } ] }, { "uniprot_ac": "P54755", "gene_name": "EPHA5", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "P54755", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P54755" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "P54755", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P54755" } ] } ] }, { "uniprot_ac": "Q00944", "gene_name": "PTK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q00944", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q00944" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "Q00944", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q00944" } ] } ] }, { "uniprot_ac": "Q02977", "gene_name": "YRK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q02977", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q02977" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "Q02977", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q02977" } ] } ] }, { "uniprot_ac": "Q05876", "gene_name": "FYN", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q05876", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q05876" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "Q05876", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q05876" } ] } ] }, { "uniprot_ac": "Q07494", "gene_name": "EPHB1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q07494", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q07494" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "Q07494", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q07494" } ] } ] }, { "uniprot_ac": "Q07496", "gene_name": "EPHA4", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q07496", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q07496" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "Q07496", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q07496" } ] } ] }, { "uniprot_ac": "Q07497", "gene_name": "EPHB5", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q07497", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q07497" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "Q07497", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q07497" } ] } ] }, { "uniprot_ac": "Q07498", "gene_name": "EPHB3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q07498", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q07498" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "Q07498", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q07498" } ] } ] }, { "uniprot_ac": "Q08156", "gene_name": "KIT", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q08156", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08156" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "Q08156", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08156" } ] } ] }, { "uniprot_ac": "Q5F352", "gene_name": "NRAS", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "Q5F352", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F352" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "Q5F352", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F352" } ] } ] }, { "uniprot_ac": "Q5ZIU3", "gene_name": "DYRK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5ZIU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZIU3" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q5ZIU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZIU3" } ] } ] }, { "uniprot_ac": "Q6XUX0", "gene_name": "DSTYK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q6XUX0", "database": "UniProtKB", "url": 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trafficking protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990475" }, "gene_names": [ { "name": "TOM1", "type": "recommended", "evidence": [ { "id": "O12940", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O12940" } ] }, { "name": "TOM-1B", "type": "synonym", "evidence": [ { "id": "NP_990475", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990475" } ] }, { "name": "TOM1", "type": "synonym", "evidence": [ { "id": "NP_990475", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990475" } ] }, { "name": "tom-1A", "type": "synonym", "evidence": [ { "id": "NP_990475", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990475" } ] } ], "protein_names": [ { "name": "Target of Myb1 membrane trafficking protein", "type": "recommended", "evidence": [ { "id": "O12940", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O12940/entry#names_and_taxonomy" } ] }, { "name": "Target of Myb protein 1", "type": "synonym", "evidence": [ { "id": "O12940", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O12940/entry#names_and_taxonomy" } ] }, { "name": "Tom-1", "type": "synonym", "evidence": [ { "id": "O12940", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O12940/entry#names_and_taxonomy" } ] }, { "name": "target of Myb protein 1", "type": "synonym", "evidence": [ { "id": "NP_990475", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990475" } ] }, { "name": "target of Myb1 membrane trafficking protein", "type": "synonym", "evidence": [ { "id": "NP_990475", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990475" } ] }, { "name": "tom-1", "type": "synonym", "evidence": [ { "id": "NP_990475", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990475" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: Y08741.1, SRR13267654.211457.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000012.1.", "evidence": [ { "database": "RefSeq", "id": "NP_990475", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990475" } ] }, { "annotation": "Adapter protein that plays a role in the intracellular membrane trafficking of ubiquitinated proteins, thereby participating in autophagy, ubiquitination-dependent signaling and receptor recycling pathways (By similarity). Acts as a MYO6/Myosin VI adapter protein that targets MYO6 to endocytic structures (By similarity). Together with MYO6, required for autophagosomal delivery of endocytic cargo, the maturation of autophagosomes and their fusion with lysosomes (By similarity). MYO6 links TOM1 with autophagy receptors, such as TAX1BP1; CALCOCO2/NDP52 and OPTN (By similarity). Binds to polyubiquitinated proteins via its GAT domain (By similarity). In a complex with TOLLIP, recruits ubiquitin-conjugated proteins onto early endosomes (By similarity). The Tom1-Tollip complex may regulate endosomal trafficking by linking polyubiquitinated proteins to clathrin (By similarity). Mediates clathrin recruitment to early endosomes (By similarity). Modulates binding of TOLLIP to phosphatidylinositol 3-phosphate (PtdIns(3)P) via binding competition; the association with TOLLIP may favor the release of TOLLIP from endosomal membranes, allowing TOLLIP to commit to cargo trafficking (By similarity). Acts as a phosphatidylinositol 5-phosphate (PtdIns(5)P) effector by binding to PtdIns(5)P, thereby regulating endosomal maturation (By similarity). PtdIns(5)P-dependent recruitment to signaling endosomes may block endosomal maturation (By similarity). Also inhibits Toll-like receptor (TLR) signaling and participates in immune receptor recycling (By similarity).", "evidence": [ { "database": "UniProtKB", "id": "O12940", "url": "https://www.uniprot.org/uniprotkb/O12940#function" }, { "database": "UniProtKB", "id": "O60784", "url": "https://www.uniprot.org/uniprotkb/O60784#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "O12940", "url": "https://www.uniprot.org/uniprotkb/O12940" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TOM1", "url": "https://www.uniprot.org/uniprotkb/O12940", "locus": { "chromosome": "1", "start_pos": 52158176, "end_pos": 52179884, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010015191", "url": 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"https://www.ebi.ac.uk/interpro/entry/IPR004152", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008942", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008942", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014645", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014645", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038425", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038425", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:396049", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:396049", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GNHKSDM", "url": "https://omabrowser.org/oma/group/GNHKSDM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2UMT0", "url": "https://www.orthodb.org/?gene=A0A3Q2UMT0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YK85", "url": "https://www.orthodb.org/?gene=A0A8V0YK85", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YK95", "url": "https://www.orthodb.org/?gene=A0A8V0YK95", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YYF6", "url": "https://www.orthodb.org/?gene=A0A8V0YYF6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "O12940", "url": "https://www.orthodb.org/?gene=O12940", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13856", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13856", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13856:SF32", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13856:SF32", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00790", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00790", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03127", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03127", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:O12940", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:O12940", "database": "PRO", "categories": [ "Protein" ] }, { "id": "R-GGA-6798695", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_990475", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990475", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q2UMT0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UMT0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2UMT0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UMT0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YK85", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK85", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YK85-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK85-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YK95", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK95", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YK95-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK95-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YYF6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYF6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YYF6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYF6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "O12940", "url": "https://www.uniprot.org/uniprotkb/O12940", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "O12940-1", "url": "https://www.uniprot.org/uniprotkb/O12940-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "O12940-2", "url": "https://www.uniprot.org/uniprotkb/O12940-2", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDFLLGNPFSSPVGQRIERATDGSLRGEDWSLNMEICDIINETEEGPKDAFRAIKKRIVGNKNFHEVMLALTVLETCVKNCGHRFHILVASQDFVESVLVRTILPKNNPPAIVHDKVLTLIQSWADAFRSSPDLTGVVAVYEDLRRKGLEFPMTDLDMLSPIHTPRRSVYSSNSQSGQNSPAVNSPQQMESILHPVTLPSGRDTSSNVPITPTQEQIKKLRSELEVVNGNVKVMSEMLTELVPSQAETSDLELLQELNRTCRAMQQRVLELIPRVQHEQLTEELLLINDNLNNVFLRHERFERVRTGQPVKAPSEAENNLIDLRPSTPPAVRQPEVTNNLSSQLAGMTLGSRSVSAGLHSLDTSGKLEEEFDMFAVTRGSSLAEQRREVKYEDPQATKGLAGALDARQQNTGAEESSASSDGAQLTNWMMRQGMVPVPQANFMEDIEKWLSTDVGESEDGKGVTSEEFDKFLEERAKVADRLPTLSSSSAGTPVSPAAASRHQKQAKEDDAMFAL", "length": 515, "header": "sp|O12940-1|TOM1_CHICK Isoform 1 of Target of Myb1 membrane trafficking protein OS=Gallus gallus OX=9031 GN=TOM1 PE=2 SV=2 CANONICAL=O12940-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2UMT0-1", "url": "https://www.uniprot.org/uniprotkb/O12940/entry#A0A3Q2UMT0-1", "sequence": { "sequence": "MDFLLGNPFSSPVGQRIERATDGSLRGEDWSLNMEICDIINETEEGPKDAFRAIKKRIVGNKNFHEVMLALTVLETCVKNCGHRFHILVASQDFVESVLVRTILPKNNPPAIVHDKVLTLIQSWADAFRSSPDLTGVVAVYEDLRRKGLEFPMTDLDMLSPIHTPRRSVYSSNSQSGQNSPAVNSPQQMESILHPVTLPSGRDTSSNVPITPTQEQIKKLRSELEVVNGNVKVMSEMLTELVPSQAETSDLELLQELNRTCRAMQQRVLELIPRVQHEQLTEELLLINDNLNNVFLRHERFERVRTGQPVKAPSEAENNLIDLRPSTPPAVRQPEVTNNLSSQLAGMTLGSRSVSAGLHSLDTSGKLEEEFDMFAVTRGSSLAEQRREVKYEDPQATKGLAGALDARQQNTGAVPVPQANFMEDIEKWLSTDVGESEDGKGVTSEEFDKFLEERAKVADRLPTLSSSSAGTPVSPAAASRHQKQAKEDDAMFAL", "length": 494, "header": "tr|A0A3Q2UMT0-1|TOM1_CHICK Computationally mapped isoform of Target of Myb1 membrane trafficking protein OS=Gallus gallus OX=9031 GN=TOM1 PE=2 SV=1 CANONICAL=O12940-1" }, "locus": { "chromosome": "1", "start_pos": 52179868, "end_pos": 52160438, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036615.1", "url": "https://www.ensembl.org/id/ENSGALT00010036615.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021350.1", "url": "https://www.ensembl.org/id/ENSGALP00010021350.1" } ] } }, { "isoform_ac": "A0A8V0YK85-1", "url": "https://www.uniprot.org/uniprotkb/O12940/entry#A0A8V0YK85-1", "sequence": { "sequence": "MPKDAFRAIKKRIVGNKNFHEVMLALTVLETCVKNCGHRFHILVASQDFVESVLVRTILPKNNPPAIVHDKVLTLIQSWADAFRSSPDLTGVVAVYEDLRRKGLEFPMTDLDMLSPIHTPRRSVYSSNSQSGQNSPAVNSPQQMESILHPVTLPSGRDTSSNVPITPTQEQIKKLRSELEVVNGNVKVMSEMLTELVPSQAETSDLELLQELNRTCRAMQQRVLELIPRVQHEQLTEELLLINDNLNNVFLRHERFERVRTGQPVKAPSEAENNLIDLRPSTPPAVRQPEVTNNLSSQLAGMTLGSRSVSAGLHSLDTSGKLEEEFDMFAVTRGSSLAEQRREVKYEDPQATKGLAGALDARQQNTGAEESSASSDGAQLTNWMMRQGMVPVPQANFMEDIEKWLSTDVGESEDGKGVTSEEFDKFLEERAKVADRLPTLSSSSAGTPVSPAAASRHQKQAKEDDAMFAL", "length": 470, "header": "tr|A0A8V0YK85-1|TOM1_CHICK Computationally mapped isoform of Target of Myb1 membrane trafficking protein OS=Gallus gallus OX=9031 GN=TOM1 PE=2 SV=1 CANONICAL=O12940-1" }, "locus": { "chromosome": "1", "start_pos": 52171723, "end_pos": 52160438, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036610.1", "url": "https://www.ensembl.org/id/ENSGALT00010036610.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021345.1", "url": "https://www.ensembl.org/id/ENSGALP00010021345.1" } ] } }, { "isoform_ac": "A0A8V0YK95-1", "url": "https://www.uniprot.org/uniprotkb/O12940/entry#A0A8V0YK95-1", "sequence": { "sequence": "MDFLLGNPFSSPVGQRIERATDGSLRGEDWSLNMEICDIINETEEGPKDAFRAIKKRIVGNKNFHEVMLALTVLETCVKNCGHRFHILVASQDFVESVLVRTILPKNNPPAIVHDKVLTLIQSWADAFRSSPDLTGVVAVYEDLRRKGLEFPMTDLDMLSPIHTPRRSVYSSNSQSGQNSPAVNSPQQMESILHPVTLPSGRDTSSNVPITPTQEQIKKLRSELEVVNGNVKVMSEMLTELVPSQAETSDLELLQELNRTCRAMQQRVLELIPRVQHEQLTEELLLINDNLNNVFLRHERFERVRTGQPVKAPSEAENNLIDLRPSTPPAVRQPEVTNNLSSQLAGMTLGSRSVSAGLHSLDTSGKLEEEFDMFAVTRGSSLAEQRREVKYEDPQATKGLAGALDARQQNTGAVIPQANFMEDIEKWLSTDVGESEDGKGVTSEEFDKFLEERAKVADRLPTLSSSSAGTPVSPAAASRHQKQAKEDDAMFAL", "length": 493, "header": "tr|A0A8V0YK95-1|TOM1_CHICK Computationally mapped isoform of Target of Myb1 membrane trafficking protein OS=Gallus gallus OX=9031 GN=TOM1 PE=2 SV=1 CANONICAL=O12940-1" }, "locus": { "chromosome": "1", "start_pos": 52179868, "end_pos": 52160438, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036623.1", "url": "https://www.ensembl.org/id/ENSGALT00010036623.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021356.1", "url": "https://www.ensembl.org/id/ENSGALP00010021356.1" } ] } }, { "isoform_ac": "A0A8V0YYF6-1", "url": "https://www.uniprot.org/uniprotkb/O12940/entry#A0A8V0YYF6-1", "sequence": { "sequence": "MDFLLGNPFSSPVGQRIERATDGSLRGEDWSLNMEICDIINETEEGPKDAFRAIKKRIVGNKNFHEVMLALTVLETCVKNCGHRFHILVASQDFVESVLVRTILPKNNPPAIVHDKVLTLIQSWADAFRSSPDLTGVVAVYEDLRRKGLEFPMTDLDMLSPIHTPRRSVYSSNSQSGQNSPAVNSPQQMESILHPVTLPSGRDTSSNVPITPTQEQIKKLRSELEVVNGNVKVMSEMLTELVPSQAETSDLELLQELNRTCRAMQQRVLELIPRVQHEQLTEELLLINDNLNNVFLRHERFERVRTGQPVKAPSEAENNLIDLRPSTPPAVRQPEVTNNLSSQLAGMTLGSRSVSAGLHSLDTSGKLEEEFDMFAVTRGSSLAEQRREVKYEDPQATKGLAGALDARQQNTGAEESSASSDGAQLTNWMMRAGTAVIWATISGESEDGKGVTSEEFDKFLEERAKVADRLPTLSSSSAGTPVSPAAASRHQKQAKEDDAMFAL", "length": 503, "header": "tr|A0A8V0YYF6-1|TOM1_CHICK Computationally mapped isoform of Target of Myb1 membrane trafficking protein OS=Gallus gallus OX=9031 GN=TOM1 PE=2 SV=1 CANONICAL=O12940-1" }, "locus": { "chromosome": "1", "start_pos": 52179868, "end_pos": 52160438, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036630.1", "url": "https://www.ensembl.org/id/ENSGALT00010036630.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021363.1", "url": "https://www.ensembl.org/id/ENSGALP00010021363.1" } ] } }, { "isoform_ac": "O12940-1", "url": "https://www.uniprot.org/uniprotkb/O12940/entry#O12940-1", "sequence": { "sequence": "MDFLLGNPFSSPVGQRIERATDGSLRGEDWSLNMEICDIINETEEGPKDAFRAIKKRIVGNKNFHEVMLALTVLETCVKNCGHRFHILVASQDFVESVLVRTILPKNNPPAIVHDKVLTLIQSWADAFRSSPDLTGVVAVYEDLRRKGLEFPMTDLDMLSPIHTPRRSVYSSNSQSGQNSPAVNSPQQMESILHPVTLPSGRDTSSNVPITPTQEQIKKLRSELEVVNGNVKVMSEMLTELVPSQAETSDLELLQELNRTCRAMQQRVLELIPRVQHEQLTEELLLINDNLNNVFLRHERFERVRTGQPVKAPSEAENNLIDLRPSTPPAVRQPEVTNNLSSQLAGMTLGSRSVSAGLHSLDTSGKLEEEFDMFAVTRGSSLAEQRREVKYEDPQATKGLAGALDARQQNTGAEESSASSDGAQLTNWMMRQGMVPVPQANFMEDIEKWLSTDVGESEDGKGVTSEEFDKFLEERAKVADRLPTLSSSSAGTPVSPAAASRHQKQAKEDDAMFAL", "length": 515, "header": "sp|O12940-1|TOM1_CHICK Isoform 1 of Target of Myb1 membrane trafficking protein OS=Gallus gallus OX=9031 GN=TOM1 PE=2 SV=2 CANONICAL=O12940-1" }, "locus": { "chromosome": "1", "start_pos": 52179868, "end_pos": 52160438, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036627.1", "url": "https://www.ensembl.org/id/ENSGALT00010036627.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021360.1", "url": "https://www.ensembl.org/id/ENSGALP00010021360.1" } ] } }, { "isoform_ac": "O12940-2", "url": "https://www.uniprot.org/uniprotkb/O12940/entry#O12940-2", "sequence": { "sequence": "MICYSCKKGPGWRGNLMRASGRGFILLAWMDCFPQSAWIRWVKYEDPQATKGLAGALDARQQNTGAVPVPQANFMEDIEKWLSTDVGESEDGKGVTSEEFDKFLEERAKVADRLPTLSSSSAGTPVSPAAASRHQKQAKEDDAMFAL", "length": 147, "header": "sp|O12940-2|TOM1_CHICK Isoform 2 of Target of Myb1 membrane trafficking protein OS=Gallus gallus OX=9031 GN=TOM1 PE=2 SV=2 CANONICAL=O12940-1" }, "locus": { "chromosome": "1", "start_pos": 52163990, "end_pos": 52160438, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036603.1", "url": "https://www.ensembl.org/id/ENSGALT00010036603.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021340.1", "url": "https://www.ensembl.org/id/ENSGALP00010021340.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 211, "start_aa": "Thr", "end_pos": 211, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr211", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 213, "start_aa": "Thr", "end_pos": 213, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr213", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 377, "start_aa": "Thr", "end_pos": 377, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr377", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "tom-1, a novel v-Myb target gene expressed in AMV- and E26-transformed myelomonocytic cells.", "journal": "EMBO J.", "date": "1997", "authors": "Burk O, Worpenberg S, Haenig B, Klempnauer K H", "evidence": [ { "database": "UniProtKB", "id": "O12940", "url": "https://www.uniprot.org/uniprotkb/O12940" } ], "reference": [ { "type": "PubMed", "id": "9135152", "url": "https://glygen.org/publication/PubMed/9135152" } ] } ], "pathway": [ { "id": "gga:396049", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:396049", "resource": "KEGG Pathway" }, { "id": "R-GGA-6798695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798695", "resource": "Reactome", "description": "Neutrophil degranulation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A9J7FQP2-1", "protein_name": "Target of Myb protein 1 isoform X1", "gene_name": "Tom1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDFLLGNPFSSPVGQRIEKATDGSLQSEDWALNMEICDIINETEEGPKDAFRAVKKRIVGNRNFHEVMLALTVLETCVKNCGHRFHVLVASQDFVESVLVRTILPKNNPPTIVHDKVLNLIQVPGQGRLIEKKVSSGYRPCPLVPSQSWADAFRSSPDLTGVVAVYEDLRRKGLEFPMTDLDMLSPIHTPQRTVFSSETPSGQNSVGCDTSQRGDLSQHATPLPTPAVLPGDSPITPTPEQIGKLRSELEMVSGNVRVMSEMLTELVPTQIEPTDLELLQELNRTCRAMQQRVLELIPRISNEQLTEELLMVNDNLNNVFLRHERFERFRTGQTGKASSEADPAADLIDMGPDPAATSNISSQLARMNLGSSSVRAGLQSLETSGHLEDDFDMFALTRGSSLADQRKGVKYEAPQTTDGLAGALDARQQNTRAIPATQARIMEDIEQWLSTDVGNSAEEPSGVTSEEFDKFLEERAKAADRLPNLASPSAEGPPRPSLGTAPRKKTQEKDDDMLFAL", "length": 517 }, "evidence": [ { "id": "O12940", "url": "https://omabrowser.org/oma/group/O12940/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "O60784-1", "protein_name": "Target of Myb1 membrane trafficking protein", "gene_name": "TOM1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDFLLGNPFSSPVGQRIEKATDGSLQSEDWALNMEICDIINETEEGPKDALRAVKKRIVGNKNFHEVMLALTVLETCVKNCGHRFHVLVASQDFVESVLVRTILPKNNPPTIVHDKVLNLIQSWADAFRSSPDLTGVVTIYEDLRRKGLEFPMTDLDMLSPIHTPQRTVFNSETQSGQDSVGTDSSQQEDSGQHAAPLPAPPILSGDTPIAPTPEQIGKLRSELEMVSGNVRVMSEMLTELVPTQAEPADLELLQELNRTCRAMQQRVLELIPQIANEQLTEELLIVNDNLNNVFLRHERFERFRTGQTTKAPSEAEPAADLIDMGPDPAATGNLSSQLAGMNLGSSSVRAGLQSLEASGRLEDEFDMFALTRGSSLADQRKEVKYEAPQATDGLAGALDARQQSTGAIPVTQACLMEDIEQWLSTDVGNDAEEPKGVTSEEFDKFLEERAKAADRLPNLSSPSAEGPPGPPSGPAPRKKTQEKDDDMLFAL", "length": 492 }, "evidence": [ { "id": "O12940", "url": "https://omabrowser.org/oma/group/O12940/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "O88746-1", "protein_name": "Target of Myb1 membrane trafficking protein", "gene_name": "Tom1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDFLLGNPFSSPVGQRIEKATDGSLQSEDWALNMEICDIINETEEGPKDAFRAVKKRIMGNKNFHEVMLALTVLETCVKNCGHRFHVLVANQDFVENVLVRTILPKNNPPTIVHDKVLNLIQSWADAFRSSPDLTGVVAVYEDLRRKGLEFPMTDLDMLSPIHTPQRTVFNSETPSRQNSVSSNTSQRGDLSQHATPLPTPAVLPGDSPITPTPEQIGKLRSELEMVSGNVRVMSEMLTELVPTQVEPADLELLQELNRTCRAMQQRILELIPRISNEQLTEELLMINDNLNNVFLRHERFERFRTGQTAKASSEAELATDLIDMGPDPAATNNLSSQLAGMNLGSRSVRAGLQSLETSGHLEDDFDMFALTRGSSLADQRKGVKYEAPQTTDGLAGALDARQQSTGAIPATQARIMEDIEQWLSTDVGNSAEEPSGVTSEEFDKFLEERAKAADRLPNLASPSAEGPPRPSPGTAPRRKTQEKDDDMLFAL", "length": 492 }, "evidence": [ { "id": "O12940", "url": "https://omabrowser.org/oma/group/O12940/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VSZ1-1", "protein_name": "TOM1-like protein 2", "gene_name": "DmTOM1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MASFFNVGALGNVFSTPVGQRIEAATDANLASENWAANMEICDMINESSDTARDAMRAIRKRLSQNAGKNNQVVMYTLTVLETCVKNCGKAFHVLVAQKDFINELVKLIGPKNDPPAAMQEKVLSLIQIWADAFKNQPDLNGVTQMYMELKNKGIEFPANDLDAMAPIYTPQRSVPEMPPQLVAAQQHTISPQHMAAAAAAAAAAAAPPSTGPLHLTPEQAAKLRSELEIVSNNMSILSEMLSVLKPGQESPDDYALLNELTSTCKEMQSRIVDLIGRVQDDELTAEFLRINDELNNVFLRHQRYEKNRSQGQGAGVTSPSAVLGAAMGLPGVGAAGAGATTVATLPPPPTTTAVSNTPQSDQLLIDLIESSEEAQLPQSLGQISLGGGAPIGVQRSARPADEFDMLAQSRTDGNHKSDLLRDIPSVDAAAGSVTATASPYKPNQPQQAQRSAGEPPVVSKSTKENEIDEMEAWLGSSHIEGIEELTSSEFDKFLEERAAAAENLPTISASNSAASATTGSAGADSLRKTPKKPGAEEDLLAL", "length": 543 }, "evidence": [ { "id": "O12940", "url": "https://omabrowser.org/oma/group/O12940/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "R4GEE3-1", "protein_name": "TOM1-like protein 2", "gene_name": "tom1l2b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": 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"https://www.uniprot.org/uniprotkb/O12940" } ], "pmid": "" }, { "name": "polyubiquitin modification-dependent protein binding", "id": "GO:0031593", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031593", "evidence": [ { "database": "UniProtKB", "id": "O12940", "url": "https://www.uniprot.org/uniprotkb/O12940" } ], "pmid": "" }, { "name": "clathrin binding", "id": "GO:0030276", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030276", "evidence": [ { "database": "UniProtKB", "id": "O12940", "url": "https://www.uniprot.org/uniprotkb/O12940" } ], "pmid": "" }, { "name": "ubiquitin binding", "id": "GO:0043130", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043130", "evidence": [ { "database": "UniProtKB", "id": "O12940", "url": "https://www.uniprot.org/uniprotkb/O12940" } ], "pmid": "" }, { "name": "myosin VI binding", "id": "GO:0070853", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070853", "evidence": [ { "database": "UniProtKB", "id": "O12940", "url": 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"https://www.uniprot.org/uniprotkb/O12940" } ], "pmid": "" }, { "name": "early endosome", "id": "GO:0005769", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005769", "evidence": [ { "database": "UniProtKB", "id": "O12940", "url": "https://www.uniprot.org/uniprotkb/O12940" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "O12940", "url": "https://www.uniprot.org/uniprotkb/O12940" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "O12940", "url": "https://www.uniprot.org/uniprotkb/O12940" } ], "pmid": "" }, { "name": "early endosome membrane", "id": "GO:0031901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031901", "evidence": [ { "database": "UniProtKB", "id": "O12940", "url": "https://www.uniprot.org/uniprotkb/O12940" } ], "pmid": "" }, { "name": "endosome 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regulation of autophagosome maturation", "id": "GO:1901098", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901098", "evidence": [ { "database": "UniProtKB", "id": "O12940", "url": "https://www.uniprot.org/uniprotkb/O12940" } ], "pmid": "" }, { "name": "regulation of endosome organization", "id": "GO:1904978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904978", "evidence": [ { "database": "UniProtKB", "id": "O12940", "url": "https://www.uniprot.org/uniprotkb/O12940" } ], "pmid": "" }, { "name": "substrate localization to autophagosome", "id": "GO:0061753", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061753", "evidence": [ { "database": "UniProtKB", "id": "O12940", "url": "https://www.uniprot.org/uniprotkb/O12940" } ], "pmid": "" }, { "name": "autophagosome-lysosome fusion", "id": "GO:0061909", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061909", "evidence": [ { "database": "UniProtKB", "id": "O12940", "url": "https://www.uniprot.org/uniprotkb/O12940" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 258, "end_pos": 260, "annotation": "n_glycosylation_sequon" }, { "start_pos": 339, "end_pos": 341, "annotation": "n_glycosylation_sequon" }, { "start_pos": 41, "end_pos": 43, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-O12940-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 515, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-O12940-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/O12940" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "O12940", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O12940" }, { "id": "PRU00373", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00373" } ], "ann_type": 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} ] }, { "uniprot_canonical_ac": "E1C656-1", "uniprot_ac": "E1C656", "uniprot_id": "HACE1_CHICK", "mass": { "chemical_mass": 106295.0, "monoisotopic_mass": 106295.0 }, "refseq": { "ac": "NP_001265084", "name": "E3 ubiquitin-protein ligase HACE1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001265084" }, "gene_names": [ { "name": "HACE1", "type": "recommended", "evidence": [ { "id": "E1C656", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C656" } ] }, { "name": "HACE1", "type": "synonym", "evidence": [ { "id": "NP_001265084", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001265084" } ] }, { "name": "RCJMB04_37k12", "type": "synonym", "evidence": [ { "id": "E1C656", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C656" } ] } ], "protein_names": [ { "name": "E3 ubiquitin-protein ligase HACE1", "type": "recommended", "evidence": [ { "id": "E1C656", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C656/entry#names_and_taxonomy" } ] }, { "name": "2.3.2.26", "type": "synonym", "evidence": [ { "id": "E1C656", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C656/entry#names_and_taxonomy" } ] }, { "name": "E3 ubiquitin-protein ligase HACE1", "type": "synonym", "evidence": [ { "id": "NP_001265084", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001265084" } ] }, { "name": "HECT domain and ankyrin repeat-containing E3 ubiquitin-protein ligase 1", "type": "synonym", "evidence": [ { "id": "E1C656", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C656/entry#names_and_taxonomy" } ] }, { "name": "HECT-type E3 ubiquitin transferase HACE1", "type": "synonym", "evidence": [ { "id": "NP_001265084", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001265084" }, { "id": "E1C656", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C656/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR13267655.83714.1, SRR13267661.3916.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000065.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001265084", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001265084" } ] }, { "annotation": "E3 ubiquitin-protein ligase involved in Golgi membrane fusion and regulation of small GTPases. Acts as a regulator of Golgi membrane dynamics during the cell cycle: recruited to Golgi membrane by Rab proteins and regulates postmitotic Golgi membrane fusion. Acts by mediating ubiquitination during mitotic Golgi disassembly, ubiquitination serving as a signal for Golgi reassembly later, after cell division.", "evidence": [ { "database": "UniProtKB", "id": "E1C656", "url": "https://www.uniprot.org/uniprotkb/E1C656#function" }, { "database": "UniProtKB", "id": "Q8IYU2", "url": "https://www.uniprot.org/uniprotkb/Q8IYU2#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1C656", "url": "https://www.uniprot.org/uniprotkb/E1C656" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "HACE1", "url": "https://www.uniprot.org/uniprotkb/E1C656", "locus": { "chromosome": "3", "start_pos": 68758256, "end_pos": 68714149, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012419", "url": "https://www.ensembl.org/id/ENSGALG00010012419" } ] } } ], "crossref": [ { "id": "E1C656", "url": "https://alphafold.ebi.ac.uk/entry/E1C656", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000015415", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000015415", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00078", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00078", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "421788", "url": "https://www.ncbi.nlm.nih.gov/gene/421788", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000569", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000569", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035983", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035983", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050409", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050409", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:421788", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421788", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QDHQDAT", "url": "https://omabrowser.org/oma/group/QDHQDAT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q3A904", "url": "https://www.orthodb.org/?gene=A0A3Q3A904", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YEH7", "url": "https://www.orthodb.org/?gene=A0A8V0YEH7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YFN8", "url": "https://www.orthodb.org/?gene=A0A8V0YFN8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YMJ2", "url": "https://www.orthodb.org/?gene=A0A8V0YMJ2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1C656", "url": "https://www.orthodb.org/?gene=E1C656", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11254", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11254", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11254:SF363", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11254:SF363", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00632", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00632", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12796", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12796", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13637", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13637", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13857", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13857", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:E1C656", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:E1C656", "database": "PRO", "categories": [ "Protein" ] }, { "id": "R-GGA-983168", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983168", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9958825", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9958825", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001265084", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001265084", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q3A904", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3A904", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q3A904-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3A904-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YEH7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEH7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YEH7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEH7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFN8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFN8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFN8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFN8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMJ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMJ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C656", "url": "https://www.uniprot.org/uniprotkb/E1C656", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C656-1", "url": "https://www.uniprot.org/uniprotkb/E1C656-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C656-2", "url": "https://www.uniprot.org/uniprotkb/E1C656-2", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MERAMEQLNRLTRSLRRARTVELPDDNETAVYTLMPMVMADQHRSVSELLSNSKFDVNYAFGRVKRSLLHIAANCGSVECLVLLLKKGANPNYQDISGCTPLHLAARNGQKKCMSKLLEYSADVNICNNEGLTAIHWLAVNGRTELLHDLVQHVSNVDVEDAMGQTALHVACQNGHKTTVQCLLDSGADINRPNVSGATPLYFACSHGQRDTAQILLMRGAKYLPDKNGITPLDLCVQGGYGETCEVLIQYHPRLFQTIIQMTQNEDLRENMLRQVLEHLSQQSESQYLKILTSLAEVATTNGHKLLSLSSNYEAQMKSLLRIVRIFCHVFRIGPSSPSNGNDMGYNGNKTPRSQVFKVRKVYDVVRKIDVKEMNFTKHAFINQTSHEQEPLELLWHSLDEWLVLIATELMKNKRDSANITSILLKQKGPDHQDATPTPSFAAAGTESRKELSTDTGDSKTYEVAGKQEAYADCQDVISMTANRLSAVIQAFYMCCSCQMPQGMTSPRFIEFVCKHDDVLKCFVNRNPKIIFDHFHFLLECPELMSRFMHIIKAQPFKDRCEWFYEHLHSGQPDSDMVHRPVNENDILLVHRDSIFRSSCEVVSKANCAKLKQGIAVRFHGEEGMGQGVVREWFDILSSEIVNPDYALFTQSADGTTFQPNSNSSVNPDHLNYFRFAGQILGLALNHRQLVNIYFTRSFYKHILGIPVNYQDVASIDPEYAKNLQWILDNDISDLGLELTFSVETDVFGAMEEVPLKPGGASILVTQENKAEYVQLVTELRMTRAIQPQINAFLQGFHMFIPPSLIQLFDEYELELLLSGMPEIDVNDWLKNTEYTSGYERGDQVIQWFWDVVEELTQEERVLLLQFVTGSSRVPHGGFAHIMGGSGLQNFTIAAVPYTANLLPTSSTCINMLKLPEYPSKEILKDRLLVALHCGSYGYTMA", "length": 942, "header": "sp|E1C656-1|HACE1_CHICK Isoform 1 of E3 ubiquitin-protein ligase HACE1 OS=Gallus gallus OX=9031 GN=HACE1 PE=2 SV=1 CANONICAL=E1C656-1" }, "isoforms": [ { "isoform_ac": "A0A3Q3A904-1", "url": "https://www.uniprot.org/uniprotkb/E1C656/entry#A0A3Q3A904-1", "sequence": { "sequence": "MERAMEQLNRLTRSLRRARTVELPDDNETAVYTLMPMVMADQHSCGSVECLVLLLKKGANPNYQDISGCTPLHLAARNGQKKCMSKLLEYSADVNICNNEGLTAIHWLAVNGRTELLHDLVQHVSNVDVEDAMGQTALHVACQNGHKTTVQCLLDSGADINRPNVSGATPLYFACSHGQRDTAQILLMRGAKYLPDKNGITPLDLCVQGGYGETCEVLIQYHPRLFQTIIQMTQNEDLRENMLRQVLEHLSQQSESQYLKILTSLAEVATTNGHKLLSLSSNYEAQMKSLLRIVRIFCHVFRIGPSSPSNGNDMGYNGNKTPRSQVFKPLELLWHSLDEWLVLIATELMKNKRDSANITSILLKQKGPDHQDATPTPSFAAAGTESRKELSTDTGDSKTYEVAGKQEAYADCQDVISMTANRLSAVIQAFYMCCSCQMPQGMTSPRFIEFVCKHDDVLKCFVNRNPKIIFDHFHFLLECPELMSRFMHIIKAQPFKDRCEWFYEHLHSGQPDSDMVHRPVNENDILLVHRDSIFRSSCEVVSKANCAKLKQGIAVRFHGEEGMGQGVVREWFDILSSEIVNPDYALFTQSADGTTFQPNSNSSVNPDHLNYFRFAGQILGLALNHRQLVNIYFTRSFYKHILGIPVNYQDVASIDPEYAKNLQWILDNDISDLGLELTFSVETDVFGAMEEVPLKPGGASILVTQENKAEYVQLVTELRMTRAIQPQINAFLQGFHMFIPPSLIQLFDEYELELLLSGMPEIDVNDWLKNTEYTSGYERGDQVIQWFWDVVEELTQEERVLLLQFVTGSSRVPHGGFAHIMGGSGLQNFTIAAVPYTANLLPTSSTCINMLKLPEYPSKEILKDRLLVALHCGSYGYTMA", "length": 880, "header": "tr|A0A3Q3A904-1|HACE1_CHICK Computationally mapped isoform of E3 ubiquitin-protein ligase HACE1 OS=Gallus gallus OX=9031 GN=HACE1 PE=2 SV=1 CANONICAL=E1C656-1" }, "locus": { "chromosome": "3", "start_pos": 68757441, "end_pos": 68714283, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029763.1", "url": "https://www.ensembl.org/id/ENSGALT00010029763.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017325.1", "url": "https://www.ensembl.org/id/ENSGALP00010017325.1" } ] } }, { "isoform_ac": "A0A8V0YEH7-1", "url": "https://www.uniprot.org/uniprotkb/E1C656/entry#A0A8V0YEH7-1", "sequence": { "sequence": "MRGNGLKLCQDNETAVYTLMPMVMADQHRSVSELLSNSKFDVNYAFGRVKRSLLHIAANCGSVECLVLLLKKGANPNYQDISGCTPLHLAARNGQKKCMSKLLEYSADVNICNNEGLTAIHWLAVNGRTELLHDLVQHVSNVDVEDAMGQTALHVACQNGHKTTVQCLLDSGADINRPNVSGATPLYFACSHGQRDTAQILLMRGAKYLPDKNGITPLDLCVQGGYGETCEVLIQYHPRLFQTIIQMTQNEDLRENMLRQVLEHLSQQSESQYLKILTSLAEVATTNGHKLLSLSSNYEAQMKSLLRIVRIFCHVFRIGPSSPSNGNDMGYNGNKTPRSQVFKPLELLWHSLDEWLVLIATELMKNKRDSANITSILLKQKGPDHQDATPTPSFAAAGTESRKELSTDTGDSKTYEVAGKQEAYADCQDVISMTANRLSAVIQAFYMCCSCQMPQGMTSPRFIEFVCKHDDVLKCFVNRNPKIIFDHFHFLLECPELMSRFMHIIKAQPFKDRCEWFYEHLHSGQPDSDMVHRPVNENDILLVHRDSIFRSSCEVVSKANCAKLKQGIAVRFHGEEGMGQGVVREWFDILSSEIVNPDYALFTQSADGTTFQPNSNSSVNPDHLNYFRFAGQILGLALNHRQLVNIYFTRSFYKHILGIPVNYQDVASIDPEYAKNLQWILDNDISDLGLELTFSVETDVFGAMEEVPLKPGGASILVTQENKAEYVQLVTELRMTRAIQPQINAFLQGFHMFIPPSLIQLFDEYELELLLSGMPEIDVNDWLKNTEYTSGYERGDQVIQWFWDVVEELTQEERVLLLQFVTGSSRVPHGGFAHIMGGSGLQNFTIAAVPYTANLLPTSSTCINMLKLPEYPSKEILKDRLLVALHCGSYGYTMA", "length": 895, "header": "tr|A0A8V0YEH7-1|HACE1_CHICK Computationally mapped isoform of E3 ubiquitin-protein ligase HACE1 OS=Gallus gallus OX=9031 GN=HACE1 PE=2 SV=1 CANONICAL=E1C656-1" }, "locus": { "chromosome": "3", "start_pos": 68757441, "end_pos": 68715984, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029766.1", "url": "https://www.ensembl.org/id/ENSGALT00010029766.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017327.1", "url": "https://www.ensembl.org/id/ENSGALP00010017327.1" } ] } }, { "isoform_ac": "A0A8V0YFN8-1", "url": "https://www.uniprot.org/uniprotkb/E1C656/entry#A0A8V0YFN8-1", "sequence": { "sequence": "MERAMEQLNRLTRSLRRARTVELPDDNETAVYTLMPMVMADQHRSVSELLSNSKFDVNYAFGRVKRSLLHIAANCGSVECLVLLLKKGANPNYQDISGCTPLHLAARNGQKKCMSKLLEYSADVNICNNEGLTAIHWLAVNGRTELLHDLVQHVSNVDVEDAMGQTALHVACQNGHKTTVQCLLDSGADINRPNVSGATPLYFACSHGQRDTAQILLMRGAKYLPDKNGITPLDLCVQGGYGETCEVLIQYHPRLFQTIIQMTQNEDLRENMLRQVLEHLSQQSESQYLKILTSLAEVATTNGHKLLSLSSNYEAQMKSLLRIVRIFCHVFRIGPSSPSNGNDMGYNGNKTPRSQVFKVRKVYDVVRKIDVKEMNFTKHAFINQTSHEQEPLELLWHSLDEWLVLIATELMKNKRDSANITSILLKQKGPDHQDATPTPSFAAAGTESRKELSTDTGDSKTYEVAGKQEAYADCQDVISMTANRLSAVIQAFYMCCSCQMPQGMTSPRFIEFVCKHDDVLKCFVNRNPKIIFDHFHFLLECPELMSRFMHIIKAQPFKDRCEWFYEHLHSGQPDSDMVHRPVNENDILLVHRDSIFRSSCEVVSKANCAKLKQGIAVRFHGEEGMGQGVVREWFDILSSEIVNPDYALFTQSADGTTFQPNSNSSVNPDHLNYFRFAGQILGLALNHRQLVNIYFTRSFYKHILGIPVNYQDVASIDPEYAKNLQWILDNDISDLGLELTFSVETDVFGAMEEVPLKPGGASILVTQENKAEYVQLVTELRMTRAIQPQINAFLQGFHMFIPPSLIQLFDEYELELLLSGMPEIDVNDWLKNTEYTSGYERGDQVIQRYAVLLMYFWINSSYNDLISVSILSSRVPHGGFAHIMGGSGLQNFTIAAVPYTANLLPTSSTCINMLKLPEYPSKEILKDRLLVALHCGSYGYTMA", "length": 943, "header": "tr|A0A8V0YFN8-1|HACE1_CHICK Computationally mapped isoform of E3 ubiquitin-protein ligase HACE1 OS=Gallus gallus OX=9031 GN=HACE1 PE=2 SV=1 CANONICAL=E1C656-1" }, "locus": { "chromosome": "3", "start_pos": 68757441, "end_pos": 68714283, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029776.1", "url": "https://www.ensembl.org/id/ENSGALT00010029776.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017335.1", "url": "https://www.ensembl.org/id/ENSGALP00010017335.1" } ] } }, { "isoform_ac": "A0A8V0YMJ2-1", "url": "https://www.uniprot.org/uniprotkb/E1C656/entry#A0A8V0YMJ2-1", "sequence": { "sequence": "MERAMEQLNRLTRSLRRARTVELPDDNETAVYTLMPMVMADQHRSVSELLSNSKFDVNYAFGRVKRSLLHIAANCGSVECLVLLLKKGANPNYQDISGCTPLHLAARNGQKKCMSKLLEYSADVNICNNEGLTAIHWLAVNGRTELLHDLVQHVSNVDVEDAMGQTALHVACQNGHKTTVQCLLDSGADINRPNVSGATPLYFACSHGQRDTAQILLMRGAKYLPDKNGITPLDLCVQGGYGETCEVLIQYHPRLFQTIIQMTQNEDLRENMLRQVLEHLSQQSESQYLKILTSLAEVATTNGHKLLSLSSNYEAQMKSLLRIVRIFCHVFRIGPSSPSNGNDMGYNGNKTPRSQVFKVRKVYDVVRKIDVKEMNFTKHAFINQTSHEQEPLELLWHSLDEWLVLIATELMKNKRDSANITSILLKQKGPDHQDATPTPSFAAAGTESRKELSTDTGDSKTYEVAGKQEAYADCQDVISMTANRLSAVIQAFYMCCSCQMPQGMTSPRFIEFVCKHDDVLKCFVNRNPKIIFDHFHFLLECPELMSRFMHIIKAQPFKDRCEWFYEHLHSGQPDSDMVHRPVNENDILLVHRDSIFRSSCEVVSKANCAKLKQGIAVRFHGEEGMGQGVVREWFDILSSEIVNPDYALFTQSADGTTFQPNSNSSVNPDHLNYFRFAGQILGLALNHRQLVNIYFTRSFYKHILGIPVNYQDVASIDPEYAKNLQWILDNDISDLGLELTFSVETDVFGAMEEVPLKPGGASILVTQENKAEYVQLVTELRMTRAIQPQINAFLQGFHMFIPPSLIQLFDEYELWFWDVVEELTQEERVLLLQFVTGSSRVPHGGFAHIMGGSGLQNFTIAAVPYTANLLPTSSTCINMLKLPEYPSKEILKDRLLVALHCGSYGYTMA", "length": 909, "header": "tr|A0A8V0YMJ2-1|HACE1_CHICK Computationally mapped isoform of E3 ubiquitin-protein ligase HACE1 OS=Gallus gallus OX=9031 GN=HACE1 PE=2 SV=1 CANONICAL=E1C656-1" }, "locus": { "chromosome": "3", "start_pos": 68757441, "end_pos": 68714283, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029769.1", "url": "https://www.ensembl.org/id/ENSGALT00010029769.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017329.1", "url": "https://www.ensembl.org/id/ENSGALP00010017329.1" } ] } }, { "isoform_ac": "E1C656-1", "url": "https://www.uniprot.org/uniprotkb/E1C656/entry#E1C656-1", "sequence": { "sequence": "MERAMEQLNRLTRSLRRARTVELPDDNETAVYTLMPMVMADQHRSVSELLSNSKFDVNYAFGRVKRSLLHIAANCGSVECLVLLLKKGANPNYQDISGCTPLHLAARNGQKKCMSKLLEYSADVNICNNEGLTAIHWLAVNGRTELLHDLVQHVSNVDVEDAMGQTALHVACQNGHKTTVQCLLDSGADINRPNVSGATPLYFACSHGQRDTAQILLMRGAKYLPDKNGITPLDLCVQGGYGETCEVLIQYHPRLFQTIIQMTQNEDLRENMLRQVLEHLSQQSESQYLKILTSLAEVATTNGHKLLSLSSNYEAQMKSLLRIVRIFCHVFRIGPSSPSNGNDMGYNGNKTPRSQVFKVRKVYDVVRKIDVKEMNFTKHAFINQTSHEQEPLELLWHSLDEWLVLIATELMKNKRDSANITSILLKQKGPDHQDATPTPSFAAAGTESRKELSTDTGDSKTYEVAGKQEAYADCQDVISMTANRLSAVIQAFYMCCSCQMPQGMTSPRFIEFVCKHDDVLKCFVNRNPKIIFDHFHFLLECPELMSRFMHIIKAQPFKDRCEWFYEHLHSGQPDSDMVHRPVNENDILLVHRDSIFRSSCEVVSKANCAKLKQGIAVRFHGEEGMGQGVVREWFDILSSEIVNPDYALFTQSADGTTFQPNSNSSVNPDHLNYFRFAGQILGLALNHRQLVNIYFTRSFYKHILGIPVNYQDVASIDPEYAKNLQWILDNDISDLGLELTFSVETDVFGAMEEVPLKPGGASILVTQENKAEYVQLVTELRMTRAIQPQINAFLQGFHMFIPPSLIQLFDEYELELLLSGMPEIDVNDWLKNTEYTSGYERGDQVIQWFWDVVEELTQEERVLLLQFVTGSSRVPHGGFAHIMGGSGLQNFTIAAVPYTANLLPTSSTCINMLKLPEYPSKEILKDRLLVALHCGSYGYTMA", "length": 942, "header": "sp|E1C656-1|HACE1_CHICK Isoform 1 of E3 ubiquitin-protein ligase HACE1 OS=Gallus gallus OX=9031 GN=HACE1 PE=2 SV=1 CANONICAL=E1C656-1" }, "locus": { "chromosome": "3", "start_pos": 68757441, "end_pos": 68714283, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029779.1", "url": "https://www.ensembl.org/id/ENSGALT00010029779.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017338.1", "url": "https://www.ensembl.org/id/ENSGALP00010017338.1" } ] } }, { "isoform_ac": "E1C656-2", "url": "https://www.uniprot.org/uniprotkb/E1C656/entry#E1C656-2", "sequence": { "sequence": "MERAMEQLNRLTRSLRRARTVELPDDNETAVYTLMPMVMADQHRSVSELLSNSKFDVNYAFGRVKRSLLHIAANCGSVECLVLLLKKGANPNYQDISGCTPLHLAARNGQKKCMSKLLEYSADVNICNNEGLTAIHWLAVNGRTELLHDLVQHVSNVDVEDAMGQTALHVACQNGHKTTVQCLLDSGADINRPNVSGATPLYFACSHGQRDTAQILLMRGAKYLPDKNGITPLDLCVQGGYGETCEVLIQYHPRLFQTIIQMTQNEDLRENMLRQVLEHLSQQSESQYLKILTSLAEVATTNGHKLLSLSSNYEAQMKSLLRIVRIFCHVFRIGPSSPSNGNDMGYNGNKTPRSQVFKVRKVYDVVRKIDVKEMNFTKHAFINQTSHEQEPLELLWHSLDEWLVLIATELMKNKRDSANITSILLKQKGPDHQDATPTPSFAAAGTESRKELSTDTGDSKTYEVAGKQEAYADCQDVISMTANRLSAVIQAFYMCCSCQMPQGMTSPRFIEFVCKHDDVLKCFVNRNPKIIFDHFHFLLECPELMSRFMHIIKAQPFKDRCEWFYEHLHSGQPDSDMVHRPVNENDILLVHRDSIFRSSCEVVSKANCAKLKQGIAVRFHGEEGMEQPSSQTATLL", "length": 636, "header": "sp|E1C656-2|HACE1_CHICK Isoform 2 of E3 ubiquitin-protein ligase HACE1 OS=Gallus gallus OX=9031 GN=HACE1 PE=2 SV=1 CANONICAL=E1C656-1" }, "locus": { "chromosome": "3", "start_pos": 68741228, "end_pos": 68714283, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029751.1", "url": "https://www.ensembl.org/id/ENSGALT00010029751.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017319.1", "url": "https://www.ensembl.org/id/ENSGALP00010017319.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 438, "start_aa": "Thr", "end_pos": 438, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr438", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "Sequence and comparative analysis of the chicken genome provide unique perspectives on vertebrate evolution.", "journal": "Nature", "date": "2004", "authors": "", "evidence": [ { "database": "UniProtKB", "id": "E1C656", "url": "https://www.uniprot.org/uniprotkb/E1C656" } ], "reference": [ { "type": "PubMed", "id": "15592404", "url": "https://glygen.org/publication/PubMed/15592404" } ] }, { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "E1C656", "url": "https://www.uniprot.org/uniprotkb/E1C656" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:421788", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421788", "resource": "KEGG Pathway" }, { "id": "R-GGA-983168", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983168", "resource": "Reactome", "description": "Antigen processing: Ubiquitination & Proteasome degradation" }, { "id": "R-GGA-9958825", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9958825", "resource": "Reactome", "description": "Activation of STAT3 by cadherin engagement" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZBM7-1", "protein_name": "E3 ubiquitin-protein ligase HACE1", "gene_name": "Hace1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MERAMEQLNRLTRSLRRARTVELPEDNETAVYTLMPMVMADQHRSVSELLSNSKFDVNYAFGRVKRSLLHIAANCGSVECLVLLLKKGANPNYQDISGCTPLHLAARNGQKKCMSKLLEYSADVNICNNEGLTAIHWLAVNGRTELLHDLVQHVTDVDVEDAMGQTALHVACQNGHKTTVQCLLDSGADINRPNVAGATPLYFACSHGQRDTAQILLLRGAKYLPDKNGVTPLDLCVQGGYGQTCEVLIQYHPRLFQTIVQMTQNEDLRENMLRQVLQHLSQQSESQYLKILTGLAEVATTNGHKLLSLSSSYEAQMKSLLRIVRIFCHVFRIGPSSPSNGMDMGYNGNKTPRSQVFKPLELLWHSLDEWLVLIATELMKNKEDSADITSILLKQKGQDQEASCISAFEPPGPGSYERLSTGPGESKPDVLAGKQEASADCQDVISVTANRLSAVIQAFYMCCSCQMPPGMTSPRFIEFVCKHDEVLKCFVNRNPKIIFDHFHFLLECPELMSRFMHIIKAQPFKDRCEWFYEHLHSGQPDSDMVHRPVSENDILLVHRDSIFRSSCEIVSKANCAKLKQGIAVRFHGEEGMGQGVVREWFDILSNEIVNPDYALFTQSADGTTFQPNSNSYVNPDHLNYFRFAGQILGLALNHRQLVNIYFTRSFYKHILGIPVNYQDVASIDPEYAKNLQWILDNDISDLGLELTFSVETDVFGAMEEVPLKPGGGSILVTQNNKAEYVQLVTELRMTRAIQPQINAFLQGFHMFIPPSLIQLFDEYELELLLSGMPEIDVNDWIKNTEYTSGYEREDPVIQWFWEVVEDMTQEERVLLLQFVTGSSRVPHGGFANIMGGSGLQNFTIAAVPYTPNLLPTSSTCINMLKLPEYPSKEILKDRLLVALHCGSYGYTMA", "length": 909 }, "evidence": [ { "id": "E1C656", "url": "https://omabrowser.org/oma/group/E1C656/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1N6G5-1", "protein_name": "E3 ubiquitin-protein ligase HACE1", "gene_name": "HACE1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MERAMEQLNRLTRSLRRARTVELPDDNETAVYTLMPMVMADQHRSVSELLSNSKFDVNYAFGRVKRSLLHIAANCGSVECLVLLLKKGANPNYQDISGCTPLHLAARNGQKKCMSKLLEYSADVNICNNEGLTAIHWLAVNGRTELLHDLVQHVSDVDVEDAMGQTALHVACQNGHKTTVQCLLDSGADINRPNVSGATPLYFACSHGQRDTAQILLLRGAKYLSDKNGVTPLDLCVQGGYGETCEVLIQYHPRLFQTIIQMTQNEDLRENMLRQVLEHLSQQSESQYLKILTSLAEVATTNGHKLLSISSNYDAQMKSLLRIVRIFCHVFRIGPSSPSNGIDMGYNGNKTPRSQVFKPLELLWHSLDEWLVLIATELMKNKKDSTDITSILLKQKGQDQDGTSIPPFEPPGPGSYENLSTGTGESKPDVLGGKQEASADCQDVISMTANRLSAVIQAFYMCCSCQMPPGMTSPRFIEFVCKHDEVLKCFVNRNPKIIFDHFHFLLECPELMSRFMHIIKAQPFKDRCEWFYEHLHSGQPDSDMVHRPVNENDILLVHRDSIFRSSCEVVSKANCAKLKQGIAVRFHGEEGMGQGVVREWFDILSNEIVNPDYALFTQSADGTTFQPNSNSSVNPDHLNYFRFAGQILGLALNHRQLVNIYFTRSFYKHILGIPVNYQDVASIDPEYAKNLQWILDNDISDLGLELTFSVETDVFGAMEEVPLKPGGGSILVTQNNKAEYVQLVTELRMTRAIQPQINAFLQGFHMFIPPSLIQLFDEYELELLLSGMPEIDVSDWIKNTEYTSGYEREDPVIQWFWEVVEDITPEERVLLLQFVTGSSRVPHGGFANIMGGSGLQNFTIAAVPYTPNLLPTSSTCINMLKLPEYPSKEILKDRLLVALHCGSYGYTMA", "length": 909 }, "evidence": [ { "id": "E1C656", "url": "https://omabrowser.org/oma/group/E1C656/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F8W2M1-1", "protein_name": "E3 ubiquitin-protein ligase HACE1", "gene_name": "hace1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MERAMEHLNVQLNRLTRSLRRARTVELPEDSETAVYTLMPMVMADQHRSVSELLLNSKFDVNYAFGRVKRSLLHIAANCGSVECLVLLLKRGANPNYQDISGCTPLHLAARNGQKKCMGRLLEYNADVNICNNEGLTAIHWLAVNGRTELLHDLVQHVTNVDVEDAMGQTALHVACQNGHKTTVQCLLDSGADINRPNVSGATPLYFACSHGQRDTAQILLLRGAKYLPDRNGVTPLDLCVQGGYGETCEILIQHHGRLFQTLIQMTQNDDIKENMLRQVLEHVSQQNDSNYQRILTSLAEVATTNGHKLLSLSSNFEVQTKSLLRIIRIFCHVFCLGPSSPNNGNDMGYNGNKTPRSQVFKPLELLWHSLDEWLVLISTELEKEITDTTRSSSGNDIASLFLKKQEVDHSVSSENPQLLLDASSVMKTPEVYADGQDVISMIANRLSAVIQAFYMCCSCQMPHGMTSPRFIEFVCKHDEVLKCFVTRNPKIIFNHFHFLLECPELMSRFMHIIKGQPFKDRCEWFYEHLLAGQPDSDMVHRPVNENDILLVHRDSLFRSSCEVVSKSSNEKLKQGIAVRFHGEEGMGQGVVREWFDILSNEIINPDYALFTQSADGTTFQPNSNSSVNPDHLNYFRFAGQILGLALYHRQLVNIYFTRSFYKHILGIPVSYQDVSSIDPEYAKNLQWILDNDISDLGLELTFSVETDVFGTMEEVPLKPGGTTIQVTQDNKEEYVQLVTELRMTRAIQPQINAFLQGFHTFIPPSLIQLFDEYELELLLSGMPEIDVMDWKRNTEYTSGYDLQEPVIQWFWEVVENLTQEERVLLLQFVTGSSRVPHGGFAFLMGGSGLQKFTVAAVPYTSNLLPTSSTCINMLKLPEYPSKDVLRDRLLVALHCGSYGYTMA", "length": 904 }, "evidence": [ { "id": "E1C656", "url": "https://omabrowser.org/oma/group/E1C656/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q3U0D9-1", "protein_name": "E3 ubiquitin-protein ligase HACE1", "gene_name": "Hace1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MERAMEQLNRLTRSLRRARTVELPEDNETAVYTLMPMVMADQHRSVSELLSNSKFDVNYAFGRVKRSLLHIAANCGSVECLVLLLKKGANPNYQDISGCTPLHLAARNGQKKCMSKLLEYSADVNICNNEGLTAIHWLAVNGRTELLHDLVQHVTDVDVEDAMGQTALHVACQNGHKTTVQCLLDSGADINRPNVSGATPLYFACSHGQRDTAQILLLRGAKYLPDKNGVTPLDLCVQGGYGQTCEVLIQYHPRLFQTIVQMTQNEDLRENMLRQVLQHLSQQSESQYLKILTGLAEVATTNGHKLLSLSSNYDAQMKSLLRIVRIFCHVFRIGPSSPSNGIDMGYNGNKTPRSQVFKPLELLWHSLDEWLVLIATELMKNKEDSTDITSILLKQKGQDQEAPSLSAFEPPGPGSYESLPPGPGDSKPEVLAGEQEASADCQDVISVTANRLSAVIQAFYMCCSCQMPPGMTSPRFIEFVCKHDEVLKCFVNRNPKIIFDHFHFLLECPELMSRFMHIIKAQPFKDRCEWFYEHLHSGQPDSDMVHRPVSENDILLVHRDSIFRSSCEIVSKANCAKLKQGIAVRFHGEEGMGQGVVREWFDILSNEIVNPDYALFTQSADGTTFQPNSNSYVNPDHLNYFRFAGQILGLALNHRQLVNIYFTRSFYKHILGIPVNYQDVASIDPEYAKNLQWILDNDISDLGLELTFSVETDVFGAMEEVPLKPGGGSILVTQNNKAEYVQLVTELRMTRAIQPQINAFLQGFHMFIPPSLIQLFDEYELELLLSGMPEIDVNDWIKNTEYTSGYEREDPVIQWFWEVVEDITQEERVLLLQFVTGSSRVPHGGFANIMGGSGLQNFTIAAVPYTPNLLPTSSTCINMLKLPEYPSKEILKDRLLVALHCGSYGYTMA", "length": 909 }, "evidence": [ { "id": "E1C656", "url": "https://omabrowser.org/oma/group/E1C656/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "E1C656", "url": "https://www.uniprot.org/uniprotkb/E1C656" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1C656", "url": "https://www.uniprot.org/uniprotkb/E1C656" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E1C656", "url": "https://www.uniprot.org/uniprotkb/E1C656" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "E1C656", "url": "https://www.uniprot.org/uniprotkb/E1C656" } ], "pmid": "" }, { "name": "Golgi cisterna membrane", "id": "GO:0032580", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032580", "evidence": [ { "database": "UniProtKB", "id": "E1C656", "url": "https://www.uniprot.org/uniprotkb/E1C656" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "E1C656", "url": "https://www.uniprot.org/uniprotkb/E1C656" } ], "pmid": "" }, { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "E1C656", "url": "https://www.uniprot.org/uniprotkb/E1C656" } ], "pmid": "" }, { "name": "ubiquitin-protein transferase activity", "id": "GO:0004842", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004842", "evidence": [ { "database": "UniProtKB", "id": "E1C656", "url": "https://www.uniprot.org/uniprotkb/E1C656" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "E1C656", "url": "https://www.uniprot.org/uniprotkb/E1C656" } ], "pmid": "" }, { "name": "regulation of cell migration", "id": "GO:0030334", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030334", "evidence": [ { "database": "UniProtKB", "id": "E1C656", "url": "https://www.uniprot.org/uniprotkb/E1C656" } ], "pmid": "" }, { "name": "membrane fusion", "id": "GO:0061025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061025", "evidence": [ { "database": "UniProtKB", "id": "E1C656", "url": "https://www.uniprot.org/uniprotkb/E1C656" } ], "pmid": "" }, { "name": "ubiquitin-dependent protein catabolic process", "id": "GO:0006511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006511", "evidence": [ { "database": "UniProtKB", "id": "E1C656", "url": "https://www.uniprot.org/uniprotkb/E1C656" } ], "pmid": "" }, { "name": "protein K48-linked ubiquitination", "id": "GO:0070936", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070936", "evidence": [ { "database": "UniProtKB", "id": "E1C656", "url": "https://www.uniprot.org/uniprotkb/E1C656" } ], "pmid": "" }, { "name": "Golgi organization", "id": "GO:0007030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007030", "evidence": [ { "database": "UniProtKB", "id": "E1C656", "url": "https://www.uniprot.org/uniprotkb/E1C656" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 194, "end_pos": 196, "annotation": "n_glycosylation_sequon" }, { "start_pos": 27, "end_pos": 29, "annotation": "n_glycosylation_sequon" }, { "start_pos": 349, "end_pos": 351, "annotation": "n_glycosylation_sequon" }, { "start_pos": 375, "end_pos": 377, "annotation": "n_glycosylation_sequon" }, { "start_pos": 383, "end_pos": 385, "annotation": "n_glycosylation_sequon" }, { "start_pos": 419, "end_pos": 421, "annotation": "n_glycosylation_sequon" }, { "start_pos": 663, "end_pos": 665, "annotation": "n_glycosylation_sequon" }, { "start_pos": 890, "end_pos": 892, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-GGA-983140", "name": "Transfer of Ub from E2 to substrate and release of E2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0X324-1", "A0A8V0XEM6-1", "A0A8V0XJC4-1", "A0A8V0XQR1-1", "A0A8V1AC19-1", "A0A8V1AC55-1", "A0A8V1AKB8-1", "A0A8V1ALH0-1", "F1NL19-1", "F1NRC6-1", "F1NTZ8-1", "A0A8V0YHL7-1", "A0A8V0YPW4-1", "A0A8V0YRM6-1", "A0A8V0YV22-1", "A0A8V0YVP3-1", "A0A8V0Z2L5-1", "F1NL77-1", "E1C982-1", "A0A3Q2UC96-1", "Q5ZKX6-1", "Z4YJC3-1", "A0A8V0XQU7-1", "A0A8V0Y5C9-1", "A0A8V1AL09-1", "A0A8V1AML5-1", "A0A8V1AP69-1", "F1NVY8-1", "R4GIV8-1", "A0A8V0ZJ49-1", "A0A8V0ZJV9-1", "A0A8V0ZL18-1", "A0A8V0ZM17-1", "A0A8V0ZSH4-1", "A0A8V0ZVX3-1", "A0A8V0ZW26-1", "A0A8V1A0Z6-1", "A0A8V0ZZH3-1", "A0A8V1A052-1", "A0A8V1A0X2-1", "A0A8V1A1I4-1", "A0A8V1A2W7-1", "A0A8V1A5P4-1", "A0A8V1A7T1-1", "A0A8V0XTY5-1", "A0A8V0Y5B5-1", "A0A8V0YL05-1", "A0A8V0Z082-1", "A0A8V0ZS27-1", "A0A8V1A9M0-1", "E1BZ35-1", "E1C3Q9-1", "F1NC08-1", "F1P2G0-1", "A0A8V0YY10-1", "A0A8V0YYC5-1", "A0A8V0Z1W7-1", "A0A8V0Z4C8-1", "A0A8V0Z596-1", "A0A1D5P284-1", "A0A8V0ZF21-1", "A0A3Q2U2G8-1", "A0A8V1A4H7-1", "A0A8V1A1N8-1", "A0A8V1A233-1", "A0A8V1A7P9-1", "A0A8V1ACU3-1", "A0A8V0ZSA3-1", "E1C656-1", "A0A8V0Y0Q7-1", "A0A8V0Y059-1", "A0A8V0Y5C7-1", "A0A8V0YCS7-1", "A0A8V0YDQ1-1", "A0A8V0YFD9-1", "A0A8V0YGF4-1", "A0A8V0YJK8-1", "A0A8V0YLY7-1", "A0A1D5NVE2-1", "A0A8V0ZKK3-1", "A0A8V0ZKQ3-1" ], "evidence": [ { "id": "R-GGA-983140", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983140" } ] }, { "id": "R-GGA-983147", "name": "Release of E3 from polyubiquitinated substrate", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XEM6-1", "A0A8V0XJC4-1", "A0A8V1AC55-1", "A0A8V1AKB8-1", "A0A8V1ALH0-1", "F1NRC6-1", "F1NTZ8-1", "A0A8V0YHL7-1", "A0A8V0YRM6-1", "A0A8V0YV22-1", "A0A8V0YVP3-1", "A0A8V0Z2L5-1", "F1NL77-1", "E1C982-1", "A0A3Q2UC96-1", "Z4YJC3-1", "A0A8V0XQU7-1", "A0A8V0Y5C9-1", "A0A8V1AL09-1", "A0A8V1AML5-1", "A0A8V1AP69-1", "F1NVY8-1", "A0A8V0ZJ49-1", "A0A8V0ZJV9-1", "A0A8V0ZL18-1", "A0A8V0ZM17-1", "A0A8V0ZSH4-1", "A0A8V0ZVX3-1", "A0A8V0ZW26-1", "A0A8V1A0Z6-1", "A0A8V0ZZH3-1", "A0A8V1A0X2-1", "A0A8V1A2W7-1", "A0A8V1A7T1-1", "A0A8V0XTY5-1", "A0A8V0Y5B5-1", "A0A8V0YL05-1", "A0A8V0ZS27-1", "A0A8V1A9M0-1", "E1BZ35-1", "E1C3Q9-1", "F1NC08-1", "F1P2G0-1", "A0A8V0YYC5-1", "A0A8V0Z4C8-1", "A0A8V0Z596-1", "A0A1D5P284-1", "A0A8V0ZF21-1", "A0A3Q2U2G8-1", "A0A8V1A1N8-1", "A0A8V1A233-1", "A0A8V1A7P9-1", "A0A8V0ZSA3-1", "E1C656-1", "A0A8V0Y0Q7-1", "A0A8V0Y5C7-1", "A0A8V0YCS7-1", "A0A8V0YDQ1-1", "A0A8V0YGF4-1", "A0A8V0YJK8-1", "A0A8V0YLY7-1", "A0A8V0ZKK3-1", "A0A8V0ZKQ3-1" ], "evidence": [ { "id": "R-GGA-983147", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983147" } ] }, { "id": "R-GGA-983156", "name": "Polyubiquitination of substrate", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0X324-1", "A0A8V0XEM6-1", "A0A8V0XJC4-1", "A0A8V0XQR1-1", "A0A8V1AC19-1", "A0A8V1AC55-1", "A0A8V1AKB8-1", "A0A8V1ALH0-1", "F1NL19-1", "F1NRC6-1", "F1NTZ8-1", "A0A8V0YHL7-1", "A0A8V0YPW4-1", "A0A8V0YRM6-1", "A0A8V0YV22-1", "A0A8V0YVP3-1", "A0A8V0Z2L5-1", "F1NL77-1", "E1C982-1", "A0A3Q2UC96-1", "Q5ZKX6-1", "Z4YJC3-1", "A0A8V0XQU7-1", "A0A8V0Y5C9-1", "A0A8V1AL09-1", "A0A8V1AML5-1", "A0A8V1AP69-1", "F1NVY8-1", "R4GIV8-1", "A0A8V0ZJ49-1", "A0A8V0ZJV9-1", "A0A8V0ZL18-1", "A0A8V0ZM17-1", "A0A8V0ZSH4-1", "A0A8V0ZVX3-1", "A0A8V0ZW26-1", "A0A8V1A0Z6-1", "A0A8V0ZZH3-1", "A0A8V1A052-1", "A0A8V1A0X2-1", "A0A8V1A1I4-1", "A0A8V1A2W7-1", "A0A8V1A5P4-1", "A0A8V1A7T1-1", "A0A8V0XTY5-1", "A0A8V0Y5B5-1", "A0A8V0YL05-1", "A0A8V0Z082-1", "A0A8V0ZS27-1", "A0A8V1A9M0-1", "E1BZ35-1", "E1C3Q9-1", "F1NC08-1", "F1P2G0-1", "A0A8V0YY10-1", "A0A8V0YYC5-1", "A0A8V0Z1W7-1", "A0A8V0Z4C8-1", "A0A8V0Z596-1", "A0A1D5P284-1", "A0A8V0ZF21-1", "A0A3Q2U2G8-1", "A0A8V1A4H7-1", "A0A8V1A1N8-1", "A0A8V1A233-1", "A0A8V1A7P9-1", "A0A8V1ACU3-1", "A0A8V0ZSA3-1", "E1C656-1", "A0A8V0Y0Q7-1", "A0A8V0Y059-1", "A0A8V0Y5C7-1", "A0A8V0YCS7-1", "A0A8V0YDQ1-1", "A0A8V0YFD9-1", "A0A8V0YGF4-1", "A0A8V0YJK8-1", "A0A8V0YLY7-1", "A0A1D5NVE2-1", "A0A8V0ZKK3-1", "A0A8V0ZKQ3-1" ], "evidence": [ { "id": "R-GGA-983156", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983156" } ] }, { "id": "R-GGA-983157", "name": "Interaction of E3 with substrate and E2-Ub complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0X324-1", "A0A8V0XEM6-1", "A0A8V0XJC4-1", "A0A8V0XQR1-1", "A0A8V1AC19-1", "A0A8V1AC55-1", "A0A8V1AKB8-1", "A0A8V1ALH0-1", "F1NL19-1", "F1NRC6-1", "F1NTZ8-1", "A0A8V0YHL7-1", "A0A8V0YPW4-1", "A0A8V0YRM6-1", "A0A8V0YV22-1", "A0A8V0YVP3-1", "A0A8V0Z2L5-1", "F1NL77-1", "E1C982-1", "A0A3Q2UC96-1", "Q5ZKX6-1", "Z4YJC3-1", "A0A8V0XQU7-1", "A0A8V0Y5C9-1", "A0A8V1AL09-1", "A0A8V1AML5-1", "A0A8V1AP69-1", "F1NVY8-1", "R4GIV8-1", "A0A8V0ZJ49-1", "A0A8V0ZJV9-1", "A0A8V0ZL18-1", "A0A8V0ZM17-1", "A0A8V0ZSH4-1", "A0A8V0ZVX3-1", "A0A8V0ZW26-1", "A0A8V1A0Z6-1", "A0A8V0ZZH3-1", "A0A8V1A052-1", "A0A8V1A0X2-1", "A0A8V1A1I4-1", "A0A8V1A2W7-1", "A0A8V1A5P4-1", "A0A8V1A7T1-1", "A0A8V0XTY5-1", "A0A8V0Y5B5-1", "A0A8V0YL05-1", "A0A8V0Z082-1", "A0A8V0ZS27-1", "A0A8V1A9M0-1", "E1BZ35-1", "E1C3Q9-1", "F1NC08-1", "F1P2G0-1", "A0A8V0YY10-1", "A0A8V0YYC5-1", "A0A8V0Z1W7-1", "A0A8V0Z4C8-1", "A0A8V0Z596-1", "A0A1D5P284-1", "A0A8V0ZF21-1", "A0A3Q2U2G8-1", "A0A8V1A4H7-1", "A0A8V1A1N8-1", "A0A8V1A233-1", "A0A8V1A7P9-1", "A0A8V1ACU3-1", "A0A8V0ZSA3-1", "E1C656-1", "A0A8V0Y0Q7-1", "A0A8V0Y059-1", "A0A8V0Y5C7-1", "A0A8V0YCS7-1", "A0A8V0YDQ1-1", "A0A8V0YFD9-1", "A0A8V0YGF4-1", "A0A8V0YJK8-1", "A0A8V0YLY7-1", "A0A1D5NVE2-1", "A0A8V0ZKK3-1", "A0A8V0ZKQ3-1" ], "evidence": [ { "id": "R-GGA-983157", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983157" } ] }, { "id": "R-GGA-9958873", "name": "Cell-to-cell contact through homophilic cadherin interactions inhibits RAC1/CDC42 ubiquitination", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P53478-1", "A0A8V0YRF2-1", "A0A8V0Z8U4-1", "E1C656-1", "P63270-1", "Q5ZMQ2-1", "Q90694-1" ], "evidence": [ { "id": "R-GGA-9958873", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9958873" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5NVE2", "gene_name": "UBE2Q1", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A1D5NVE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVE2" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A1D5NVE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVE2" } ] } ] }, { "uniprot_ac": "A0A1D5P284", "gene_name": "UBR2", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A1D5P284", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P284" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A1D5P284", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P284" } ] } ] }, { "uniprot_ac": "A0A3Q2U2G8", "gene_name": "TRIM9", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A3Q2U2G8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U2G8" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A3Q2U2G8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U2G8" } ] } ] }, { "uniprot_ac": "A0A3Q2UC96", "gene_name": "NEDD4L", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A3Q2UC96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UC96" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A3Q2UC96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UC96" } ] } ] }, { "uniprot_ac": "A0A8V0X324", "gene_name": "UBE2E1", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0X324", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X324" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0X324", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X324" } ] } ] }, { "uniprot_ac": "A0A8V0XEM6", "gene_name": "HERC2", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0XEM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEM6" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0XEM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEM6" } ] } ] }, { "uniprot_ac": "A0A8V0XJC4", "gene_name": "UBE3D", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0XJC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJC4" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0XJC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJC4" } ] } ] }, { "uniprot_ac": "A0A8V0XQR1", "gene_name": "UBE2H", "activity": [ { "ec_number": "2.3.2.24", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E1 ubiquitin-activating enzyme]-L-cysteine + N(6)-monoubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0XQR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQR1" } ] }, { "ec_number": "2.3.2.24", "activity": "", "evidence": [ { "id": "A0A8V0XQR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQR1" } ] } ] }, { "uniprot_ac": "A0A8V0XQU7", "gene_name": "RNF6", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0XQU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQU7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0XQU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQU7" } ] } ] }, { "uniprot_ac": "A0A8V0XTY5", "gene_name": "SH3RF1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0XTY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XTY5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0XTY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XTY5" } ] } ] }, { "uniprot_ac": "A0A8V0Y059", "gene_name": "UBE2D1", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0Y059", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y059" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0Y059", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y059" } ] } ] }, { "uniprot_ac": "A0A8V0Y0Q7", "gene_name": "RNF144B", "activity": [ { "ec_number": "2.3.2.31", "activity": "[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.", "evidence": [ { "id": "A0A8V0Y0Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y0Q7" } ] }, { "ec_number": "2.3.2.31", "activity": "", "evidence": [ { "id": "A0A8V0Y0Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y0Q7" } ] } ] }, { "uniprot_ac": "A0A8V0Y5B5", "gene_name": "LTN1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Y5B5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5B5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0Y5B5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5B5" } ] } ] }, { "uniprot_ac": "A0A8V0Y5C7", "gene_name": "CBLL1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Y5C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5C7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0Y5C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5C7" } ] } ] }, { "uniprot_ac": "A0A8V0Y5C9", "gene_name": "HERC3", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Y5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5C9" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0Y5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5C9" } ] } ] }, { "uniprot_ac": "A0A8V0YCS7", "gene_name": "RNF19A", "activity": [ { "ec_number": "2.3.2.31", "activity": "[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.", "evidence": [ { "id": "A0A8V0YCS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCS7" } ] }, { "ec_number": "2.3.2.31", "activity": "", "evidence": [ { "id": "A0A8V0YCS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCS7" } ] } ] }, { "uniprot_ac": "A0A8V0YDQ1", "gene_name": "WWP1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YDQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDQ1" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0YDQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDQ1" } ] } ] }, { "uniprot_ac": "A0A8V0YFD9", "gene_name": "UBE2D2", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0YFD9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFD9" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0YFD9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFD9" } ] } ] }, { "uniprot_ac": "A0A8V0YGF4", "gene_name": "MYLIP", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YGF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGF4" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YGF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGF4" } ] } ] }, { "uniprot_ac": "A0A8V0YHL7", "gene_name": "RNF114", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YHL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHL7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YHL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHL7" } ] } ] }, { "uniprot_ac": "A0A8V0YJK8", "gene_name": "RNF14", "activity": [ { "ec_number": "2.3.2.31", "activity": "[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.", "evidence": [ { "id": "A0A8V0YJK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJK8" } ] }, { "ec_number": "2.3.2.31", "activity": "", "evidence": [ { "id": "A0A8V0YJK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJK8" } ] } ] }, { "uniprot_ac": "A0A8V0YL05", "gene_name": "UBE3A", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YL05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL05" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0YL05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL05" } ] } ] }, { "uniprot_ac": "A0A8V0YLY7", "gene_name": "MKRN4P", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLY7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLY7" } ] } ] }, { "uniprot_ac": "A0A8V0YPW4", "gene_name": "UBE2J2", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0YPW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPW4" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0YPW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPW4" } ] } ] }, { "uniprot_ac": "A0A8V0YRF2", "gene_name": "BIRC8", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YRF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRF2" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YRF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRF2" } ] } ] }, { "uniprot_ac": "A0A8V0YRM6", "gene_name": "RNF130", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YRM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRM6" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YRM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRM6" } ] } ] }, { "uniprot_ac": "A0A8V0YV22", "gene_name": "RNF4", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YV22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YV22" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YV22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YV22" } ] } ] }, { "uniprot_ac": "A0A8V0YVP3", "gene_name": "RBBP6", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YVP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVP3" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YVP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVP3" } ] } ] }, { "uniprot_ac": "A0A8V0YY10", "gene_name": "UBE2D3", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0YY10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YY10" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0YY10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YY10" } ] } ] }, { "uniprot_ac": "A0A8V0YYC5", "gene_name": "ZNRF2", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YYC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYC5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YYC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYC5" } ] } ] }, { "uniprot_ac": "A0A8V0Z082", "gene_name": "UBE2B", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0Z082", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z082" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0Z082", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z082" } ] } ] }, { "uniprot_ac": "A0A8V0Z1W7", "gene_name": "UBE2K", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0Z1W7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1W7" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0Z1W7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1W7" } ] } ] }, { "uniprot_ac": "A0A8V0Z2L5", "gene_name": "TRIM63", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Z2L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2L5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0Z2L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2L5" } ] } ] }, { "uniprot_ac": "A0A8V0Z4C8", "gene_name": "MGRN1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Z4C8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4C8" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0Z4C8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4C8" } ] } ] }, { "uniprot_ac": "A0A8V0Z596", "gene_name": "STUB1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Z596", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z596" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0Z596", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z596" } ] } ] }, { "uniprot_ac": "A0A8V0Z8U4", "gene_name": "RAC1", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0Z8U4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8U4" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0Z8U4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8U4" } ] } ] }, { "uniprot_ac": "A0A8V0ZF21", "gene_name": "DTX3L", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZF21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF21" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZF21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF21" } ] } ] }, { "uniprot_ac": "A0A8V0ZJ49", "gene_name": "SMURF1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZJ49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ49" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZJ49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ49" } ] } ] }, { "uniprot_ac": "A0A8V0ZJV9", "gene_name": "MIB2", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZJV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJV9" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZJV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJV9" } ] } ] }, { "uniprot_ac": "A0A8V0ZKK3", "gene_name": "UBE3B", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKK3" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKK3" } ] } ] }, { "uniprot_ac": "A0A8V0ZKQ3", "gene_name": "RNF25", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZKQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKQ3" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZKQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKQ3" } ] } ] }, { "uniprot_ac": "A0A8V0ZL18", "gene_name": "HECTD2", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZL18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL18" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZL18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL18" } ] } ] }, { "uniprot_ac": "A0A8V0ZM17", "gene_name": "UBR1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZM17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM17" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZM17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM17" } ] } ] }, { "uniprot_ac": "A0A8V0ZS27", "gene_name": "TRIP12", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZS27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS27" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZS27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS27" } ] } ] }, { "uniprot_ac": "A0A8V0ZSA3", "gene_name": "HERC4", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZSA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSA3" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZSA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSA3" } ] } ] }, { "uniprot_ac": "A0A8V0ZSH4", "gene_name": "RNF111", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZSH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSH4" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZSH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSH4" } ] } ] }, { "uniprot_ac": "A0A8V0ZVX3", "gene_name": "NEDD4", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZVX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVX3" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZVX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVX3" } ] } ] }, { "uniprot_ac": "A0A8V0ZW26", "gene_name": "ZNRF1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZW26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZW26" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZW26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZW26" } ] } ] }, { "uniprot_ac": "A0A8V0ZZH3", "gene_name": "ITCH", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZZH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZH3" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZZH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZH3" } ] } ] }, { "uniprot_ac": "A0A8V1A052", "gene_name": "UBE2E3", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V1A052", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A052" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V1A052", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A052" } ] } ] }, { "uniprot_ac": "A0A8V1A0X2", "gene_name": "UBE3C", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A0X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0X2" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V1A0X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0X2" } ] } ] }, { "uniprot_ac": "A0A8V1A0Z6", "gene_name": "UBE4A", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A0Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Z6" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1A0Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Z6" } ] } ] }, { "uniprot_ac": "A0A8V1A1I4", "gene_name": "UBE2Z", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V1A1I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1I4" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V1A1I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1I4" } ] } ] }, { "uniprot_ac": "A0A8V1A1N8", "gene_name": "HERC1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A1N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1N8" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V1A1N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1N8" } ] } ] }, { "uniprot_ac": "A0A8V1A233", "gene_name": "RNF220", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A233", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A233" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1A233", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A233" } ] } ] }, { "uniprot_ac": "A0A8V1A2W7", "gene_name": "RNF41", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A2W7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2W7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1A2W7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2W7" } ] } ] }, { "uniprot_ac": "A0A8V1A4H7", "gene_name": "UBE2L3", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V1A4H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4H7" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V1A4H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4H7" } ] } ] }, { "uniprot_ac": "A0A8V1A5P4", "gene_name": "UBE2G2", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V1A5P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5P4" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V1A5P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5P4" } ] } ] }, { "uniprot_ac": "A0A8V1A7P9", "gene_name": "DCAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] } ] }, { "uniprot_ac": "A0A8V1A7T1", "gene_name": "RNF123", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A7T1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7T1" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1A7T1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7T1" } ] } ] }, { "uniprot_ac": "A0A8V1A9M0", "gene_name": "RNF34", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A9M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9M0" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1A9M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9M0" } ] } ] }, { "uniprot_ac": "A0A8V1AC19", "gene_name": "UBA7", "activity": [ { "ec_number": "6.2.1.45", "activity": "ATP + ubiquitin + [E1 ubiquitin-activating enzyme]-L-cysteine = AMP + diphosphate + S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V1AC19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC19" } ] }, { "ec_number": "6.2.1.45", "activity": "", "evidence": [ { "id": "A0A8V1AC19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC19" } ] } ] }, { "uniprot_ac": "A0A8V1AC55", "gene_name": "SMURF2", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1AC55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC55" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V1AC55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC55" } ] } ] }, { "uniprot_ac": "A0A8V1ACU3", "gene_name": "UBE2O", "activity": [ { "ec_number": "2.3.2.24", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E1 ubiquitin-activating enzyme]-L-cysteine + N(6)-monoubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1ACU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACU3" } ] }, { "ec_number": "2.3.2.24", "activity": "", "evidence": [ { "id": "A0A8V1ACU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACU3" } ] } ] }, { "uniprot_ac": "A0A8V1AKB8", "gene_name": "TRIM32", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1AKB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKB8" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1AKB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKB8" } ] } ] }, { "uniprot_ac": "A0A8V1AL09", "gene_name": "TRIM37", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1AL09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL09" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1AL09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL09" } ] } ] }, { "uniprot_ac": "A0A8V1ALH0", "gene_name": "RNF213", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1ALH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALH0" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1ALH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALH0" } ] } ] }, { "uniprot_ac": "A0A8V1AML5", "gene_name": "TRIM50", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1AML5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AML5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1AML5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AML5" } ] } ] }, { "uniprot_ac": "A0A8V1AP69", "gene_name": "TRIM58", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1AP69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP69" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1AP69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP69" } ] } ] }, { "uniprot_ac": "E1BZ35", "gene_name": "RNF182", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1BZ35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BZ35" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "E1BZ35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BZ35" } ] } ] }, { "uniprot_ac": "E1C3Q9", "gene_name": "SIAH2", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor 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"https://www.ebi.ac.uk/interpro/entry/IPR002720", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013763", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013763", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015030", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015030", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028309", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028309", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036915", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036915", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:386582", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:386582", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VKDIGCI", "url": "https://omabrowser.org/oma/group/VKDIGCI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q3AS57", "url": "https://www.orthodb.org/?gene=A0A3Q3AS57", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XF76", "url": "https://www.orthodb.org/?gene=A0A8V0XF76", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XHX6", "url": "https://www.orthodb.org/?gene=A0A8V0XHX6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XHY1", "url": "https://www.orthodb.org/?gene=A0A8V0XHY1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XKP5", "url": "https://www.orthodb.org/?gene=A0A8V0XKP5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NAY3", "url": "https://www.orthodb.org/?gene=F1NAY3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13742", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13742", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13742:SF36", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13742:SF36", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01857", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01857", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01858", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01858", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08934", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08934", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF11934", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11934", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-174178", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-174178", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-2299718", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2299718", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-2559584", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2559584", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-69200", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-69200", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-69202", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-69202", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-69231", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-69231", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-69656", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-69656", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9841922", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9841922", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q3AS57", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3AS57", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q3AS57-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3AS57-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XF76", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XF76", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XF76-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XF76-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XHX6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XHX6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XHX6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XHX6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XHY1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XHY1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XHY1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XHY1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XKP5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XKP5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XKP5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XKP5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NAY3", "url": "https://www.uniprot.org/uniprotkb/F1NAY3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NAY3-1", "url": "https://www.uniprot.org/uniprotkb/F1NAY3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPPKPLRRAGAARSQRTSPEGGAGTASPPGGTRLEVGEAEFVALCDALKAPDSVREKAWMTYESLAAADGASAYNKKKKETWGVCIFIVAIDLDEMTFTFTELLKSLSISVCTFFQFLKEVDVNMDTVSTKVDSTVSRLKKKYDVLLALYHKFERTCGLIYLEQPSSEISAELSSVLVLKNYWITFLLAKGKVLQMEDDLVISFQLLLCVLDYFIKLSPPAMLKEPYKSAVTALTVNGSTRTPRRGQNRNARASKQIDTDTKVIEILCKEHDCNLDEVKNVYFTSFIPFLNSLGVVASNGLPEVDVLSKQYDELYLKNKDIDARLFLDHDETLQPDVIACSQLERTPRKNNPDEEVNHVLPQTPVRAAMNTIQQLMMILNSATDKPSDTLIAYFNNCTVNPEDSILKRVESLGHIFKKKFAEAVGQGCAEIGSQRYQLGVRLYYRVMESMLKSEEERLSVHNFSKLLNDNIFHTSLLACALEIVMATYGRTASQSDGTSAETDLSFPWILNVFDLKAFDFYKVIESFIKVEPSLTRDMIKHLERCEHRIMESLAWQSDSPLFDLIKQSKEREGQTDQPEPTSTLNLPLQHNHTAADLYLSPVRSPKKKASGHPQSGTSNPDAQPSATSQTQKPQKSTSLSLFYKKVFRLAYLRLHTLFFRLLSEHPDLEPLIWTLFQHTLQNESELMRDRHLDQIMMCSMYGICKVKNVDLRFKTIVSAYKELPNTNQETFKRVLIREEQYDSIIVFYNLVFMQKLKTNILQYASNRPPTLSPIPHIPRSPYQFSNSPRRVPAGNNIYISPLKSPYKFSDGFHSPTKMTPRSRILVSIGETFGTSEKFQKINQMVCNSESHVKRSAEPSDAPKPLKRLRFDIEGQDEADGGKHLPQESKFQQKLAEMTSTRTRMQKQKLNDGNDTSANEENCTAAVQGQGLPAEAGSSEHVVLAVLLKAVSCAAPQVRPVLQSPSSHPTHFRGPTLNFIESHRD", "length": 984, "header": "tr|A0A3Q3AS57-1|A0A3Q3AS57_CHICK Isoform 1 of Retinoblastoma-associated protein OS=Gallus gallus OX=9031 GN=RB1 PE=3 SV=1 CANONICAL=A0A3Q3AS57-1" }, "isoforms": [ { "isoform_ac": "A0A3Q3AS57-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3AS57/entry#A0A3Q3AS57-1", "sequence": { "sequence": "MPPKPLRRAGAARSQRTSPEGGAGTASPPGGTRLEVGEAEFVALCDALKAPDSVREKAWMTYESLAAADGASAYNKKKKETWGVCIFIVAIDLDEMTFTFTELLKSLSISVCTFFQFLKEVDVNMDTVSTKVDSTVSRLKKKYDVLLALYHKFERTCGLIYLEQPSSEISAELSSVLVLKNYWITFLLAKGKVLQMEDDLVISFQLLLCVLDYFIKLSPPAMLKEPYKSAVTALTVNGSTRTPRRGQNRNARASKQIDTDTKVIEILCKEHDCNLDEVKNVYFTSFIPFLNSLGVVASNGLPEVDVLSKQYDELYLKNKDIDARLFLDHDETLQPDVIACSQLERTPRKNNPDEEVNHVLPQTPVRAAMNTIQQLMMILNSATDKPSDTLIAYFNNCTVNPEDSILKRVESLGHIFKKKFAEAVGQGCAEIGSQRYQLGVRLYYRVMESMLKSEEERLSVHNFSKLLNDNIFHTSLLACALEIVMATYGRTASQSDGTSAETDLSFPWILNVFDLKAFDFYKVIESFIKVEPSLTRDMIKHLERCEHRIMESLAWQSDSPLFDLIKQSKEREGQTDQPEPTSTLNLPLQHNHTAADLYLSPVRSPKKKASGHPQSGTSNPDAQPSATSQTQKPQKSTSLSLFYKKVFRLAYLRLHTLFFRLLSEHPDLEPLIWTLFQHTLQNESELMRDRHLDQIMMCSMYGICKVKNVDLRFKTIVSAYKELPNTNQETFKRVLIREEQYDSIIVFYNLVFMQKLKTNILQYASNRPPTLSPIPHIPRSPYQFSNSPRRVPAGNNIYISPLKSPYKFSDGFHSPTKMTPRSRILVSIGETFGTSEKFQKINQMVCNSESHVKRSAEPSDAPKPLKRLRFDIEGQDEADGGKHLPQESKFQQKLAEMTSTRTRMQKQKLNDGNDTSANEENCTAAVQGQGLPAEAGSSEHVVLAVLLKAVSCAAPQVRPVLQSPSSHPTHFRGPTLNFIESHRD", "length": 984, "header": "tr|A0A3Q3AS57-1|A0A3Q3AS57_CHICK Isoform 1 of Retinoblastoma-associated protein OS=Gallus gallus OX=9031 GN=RB1 PE=3 SV=1 CANONICAL=A0A3Q3AS57-1" }, "locus": { "chromosome": "1", "start_pos": 168709057, "end_pos": 168633066, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010009039.1", "url": "https://www.ensembl.org/id/ENSGALT00010009039.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010005343.1", "url": "https://www.ensembl.org/id/ENSGALP00010005343.1" } ] } }, { "isoform_ac": "A0A8V0XF76-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3AS57/entry#A0A8V0XF76-1", "sequence": { "sequence": "MPHPCRHPRLEVGEAEFVALCDALKAPDSVREKAWMTYESLAAADGASAYNKKKKETWGVCIFIVAIDLDEMTFTFTELLKSLSISVCTFFQFLKEVDVNMDTVSTKVDSTVSRLKKKYDVLLALYHKFERTCGLIYLEQPSSEISAELSSVLVLKNYWITFLLAKGKVLQMEDDLVISFQLLLCVLDYFIKLSPPAMLKEPYKSAVTALTVNGSTRTPRRGQNRNARASKQIDTDTKVIEILCKEHDCNLDEVKNVYFTSFIPFLNSLGVVASNGLPEVDVLSKQYDELYLKNKDIDARLFLDHDETLQPDVIACSQLERTPRKNNPDEEVNHVLPQTPVRAAMNTIQQLMMILNSATDKPSDTLIAYFNNCTVNPEDSILKRVESLGHIFKKKFAEAVGQGCAEIGSQRYQLGVRLYYRVMESMLKSEEERLSVHNFSKLLNDNIFHTSLLACALEIVMATYGRTASQSDGTSAETDLSFPWILNVFDLKAFDFYKVIESFIKVEPSLTRDMIKHLERCEHRIMESLAWQSDSPLFDLIKQSKEREGQTDQPEPTSTLNLPLQHNHTAADLYLSPVRSPKKKASGHPQSGTSNPDAQPSATSQTQKPQKSTSLSLFYKKVFRLAYLRLHTLFFRLLSEHPDLEPLIWTLFQHTLQNESELMRDRHLDQIMMCSMYGICKVKNVDLRFKTIVSAYKELPNTNQETFKRVLIREEQYDSIIVFYNLVFMQKLKTNILQYASNRPPTLSPIPHIPRSPYQFSNSPRRVPAGNNIYISPLKSPYKFSDGFHSPTKMTPRSRILVSIGETFGTSEKFQKINQMVCNSESHVKRSAEPSDAPKPLKRLRFDIEGQDEADGGKHLPQESKFQQKLAEMTSTRTRMQKQKLNDGNDTSANEEK", "length": 897, "header": "tr|A0A8V0XF76-1|A0A3Q3AS57_CHICK Computationally mapped isoform of Retinoblastoma-associated protein OS=Gallus gallus OX=9031 GN=RB1 PE=3 SV=1 CANONICAL=A0A3Q3AS57-1" }, "locus": { "chromosome": "1", "start_pos": 168708385, "end_pos": 168632478, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010009044.1", "url": "https://www.ensembl.org/id/ENSGALT00010009044.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010005347.1", "url": "https://www.ensembl.org/id/ENSGALP00010005347.1" } ] } }, { "isoform_ac": "A0A8V0XHX6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3AS57/entry#A0A8V0XHX6-1", "sequence": { "sequence": "MPPKPLRRAGAARSQRTSPEGGAGTASPPGGTRLEVGEAEFVALCDALKAPDSVREKAWMTYESLAAADGASAYNKKKKETWGVCIFIVAIDLDEMTFTFTELLKSLSISVCTFFQFLKEVDVNMDTVSTKVDSTVSRLKKKYDVLLRVCRKLYSVLVLKNYWITFLLAKGKVLQMEDDLVISFQLLLCVLDYFIKLSPPAMLKEPYKSAVTALTVNGSTRTPRRGQNRNARASKQIDTDTKVIEILCKEHDCNLDEVKNVYFTSFIPFLNSLGVVASNGLPEVDVLSKQYDELYLKNKDIDARLFLDHDETLQPDVIACSQLERTPRKNNPDEEVNHVLPQTPVRAAMNTIQQLMMILNSATDKPSDTLIAYFNNCTVNPEDSILKRVESLGHIFKKKFAEAVGQGCAEIGSQRYQLGVRLYYRVMESMLKSEEERLSVHNFSKLLNDNIFHTSLLACALEIVMATYGRTASQSDGTSAETDLSFPWILNVFDLKAFDFYKVIESFIKVEPSLTRDMIKHLERCEHRIMESLAWQSDSPLFDLIKQSKEREGQTDQPEPTSTLNLPLQHNHTAADLYLSPVRSPKKKASGHPQSGTSNPDAQPSATSQTQKPQKSTSLSLFYKKVFRLAYLRLHTLFFRLLSEHPDLEPLIWTLFQHTLQNESELMRDRHLDQIMMCSMYGICKVKNVDLRFKTIVSAYKELPNTNQETFKRVLIREEQYDSIIVFYNLVFMQKLKTNILQYASNRPPTLSPIPHIPRSPYQFSNSPRRVPAGNNIYISPLKSPYKFSDGFHSPTKMTPRSRILVSIGETFGTSEKFQKINQMVCNSESHVKRSAEPSDAPKPLKRLRFDIEGQDEADGGMQKQKLNDGNDTSANEEK", "length": 879, "header": "tr|A0A8V0XHX6-1|A0A3Q3AS57_CHICK Computationally mapped isoform of Retinoblastoma-associated protein OS=Gallus gallus OX=9031 GN=RB1 PE=3 SV=1 CANONICAL=A0A3Q3AS57-1" }, "locus": { "chromosome": "1", "start_pos": 168708385, "end_pos": 168633066, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010009032.1", "url": "https://www.ensembl.org/id/ENSGALT00010009032.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010005340.1", "url": "https://www.ensembl.org/id/ENSGALP00010005340.1" } ] } }, { "isoform_ac": "A0A8V0XHY1-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3AS57/entry#A0A8V0XHY1-1", "sequence": { "sequence": "MPPKPLRRAGAARSQRTSPEGGAGTASPPGGTRLEVGEAEFVALCDALKAPDSVREKAWMTYESLAAADGASAYNKKKKETWGVCIFIVAIDLDEMTFTFTELLKSLSISVCTFFQFLKEVDVNMDTVSTKVDSTVSRLKKKYDVLLALYHKFERTCGLIYLEQPSSEISAELSSVLVLKNYWITFLLAKGKVLQMEDDLVISFQLLLCVLDYFIKLSPPAMLKEPYKSAVTALTVNGSTRTPRRGQNRNARASKQIDTDTKVIEILCKEHDCNLDEVDVLSKQYDELYLKNKDIDARLFLDHDETLQPDVIACSQLERTPRKNNPDEEVNHVLPQTPVRAAMNTIQQLMMILNSATDKPSDTLIAYFNNCTVNPEDSILKRVESLGHIFKKKFAEAVGQGCAEIGSQRYQLGVRLYYRVMESMLKSEEERLSVHNFSKLLNDNIFHTSLLACALEIVMATYGRTASQSDGTSAETDLSFPWILNVFDLKAFDFYKVIESFIKVEPSLTRDMIKHLERCEHRIMESLAWQSDSPLFDLIKQSKEREGQTDQPEPTSTLNLPLQHNHTAADLYLSPVRSPKKKASGHPQSGTSNPDAQPSATSQTQKPQKSTSLSLFYKKVFRLAYLRLHTLFFRLLSEHPDLEPLIWTLFQHTLQNESELMRDRHLDQIMMCSMYGICKVKNVDLRFKTIVSAYKELPNTNQETFKRVLIREEQYDSIIVFYNLVFMQKLKTNILQYASNRPPTLSPIPHIPRSPYQFSNSPRRVPAGNNIYISPLKSPYKFSDGFHSPTKMTPRSRILVSIGETFGTSEKFQKINQMVCNSESHVKRSAEPSDAPKPLKRLRFDIEGQDEADGGKHLPQESKFQQKLAEMTSTRTRMQKQKLNDGNDTSANEEK", "length": 895, "header": "tr|A0A8V0XHY1-1|A0A3Q3AS57_CHICK Computationally mapped isoform of Retinoblastoma-associated protein OS=Gallus gallus OX=9031 GN=RB1 PE=3 SV=1 CANONICAL=A0A3Q3AS57-1" }, "locus": { "chromosome": "1", "start_pos": 168708385, "end_pos": 168633066, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010009041.1", "url": "https://www.ensembl.org/id/ENSGALT00010009041.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010005345.1", "url": "https://www.ensembl.org/id/ENSGALP00010005345.1" } ] } }, { "isoform_ac": "A0A8V0XKP5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3AS57/entry#A0A8V0XKP5-1", "sequence": { "sequence": "MGRRLEVGEAEFVALCDALKAPDSVREKAWMTYESLAAADGASAYNKKKKETWGVCIFIVAIDLDEMTFTFTELLKSLSISVCTFFQFLKEVDVNMDTVSTKVDSTVSRLKKKYDVLLALYHKFERTCGLIYLEQPSSEISAELSSVLVLKNYWITFLLAKGKVLQMEDDLVISFQLLLCVLDYFIKLSPPAMLKEPYKSAVTALTVNGSTRTPRRGQNRNARASKQIDTDTKVIEILCKEHDCNLDEVKNVYFTSFIPFLNSLGVVASNGLPEVDVLSKQYDELYLKNKDIDARLFLDHDETLQPDVIACSQLERTPRKNNPDEEVNHVLPQTPVRAAMNTIQQLMMILNSATDKPSDTLIAYFNNCTVNPEDSILKRVESLGHIFKKKFAEAVGQGCAEIGSQRYQLGVRLYYRVMESMLKSEEERLSVHNFSKLLNDNIFHTSLLACALEIVMATYGRTASQSDGTSAETDLSFPWILNVFDLKAFDFYKVIESFIKVEPSLTRDMIKHLERCEHRIMESLAWQSDSPLFDLIKQSKEREGQTDQPEPTSTLNLPLQHNHTAADLYLSPVRSPKKKASGHPQSGTSNPDAQPSATSQTQKPQKSTSLSLFYKKVFRLAYLRLHTLFFRLLSEHPDLEPLIWTLFQHTLQNESELMRDRHLDQIMMCSMYGICKVKNVDLRFKTIVSAYKELPNTNQETFKRVLIREEQYDSIIVFYNLVFMQKLKTNILQYASNRPPTLSPIPHIPRSPYQFSNSPRRVPAGNNIYISPLKSPYKFSDGFHSPTKMTPRSRILVSIGETFGTSEKFQKINQMVCNSESHVKRSAEPSDAPKPLKRLRFDIEGQDEADGGKHLPQESKFQQKLAEMTSTRTRMQKQKLNDGNDTSANEEK", "length": 892, "header": "tr|A0A8V0XKP5-1|A0A3Q3AS57_CHICK Computationally mapped isoform of Retinoblastoma-associated protein OS=Gallus gallus OX=9031 GN=RB1 PE=3 SV=1 CANONICAL=A0A3Q3AS57-1" }, "locus": { "chromosome": "1", "start_pos": 168708385, "end_pos": 168625617, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010009049.1", "url": "https://www.ensembl.org/id/ENSGALT00010009049.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010005351.1", "url": "https://www.ensembl.org/id/ENSGALP00010005351.1" } ] } }, { "isoform_ac": "F1NAY3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3AS57/entry#F1NAY3-1", "sequence": { "sequence": "MPPKPLRRAGAARSQRTSPEGGAGTASPPGGTRLEVGEAEFVALCDALKAPDSVREKAWMTYESLAAADGASAYNKKKKETWGVCIFIVAIDLDEMTFTFTELLKSLSISVCTFFQFLKEVDVNMDTVSTKVDSTVSRLKKKYDVLLALYHKFERTCGLIYLEQPSSEISAELSSVLVLKNYWITFLLAKGKVLQMEDDLVISFQLLLCVLDYFIKLSPPAMLKEPYKSAVTALTVNGSTRTPRRGQNRNARASKQIDTDTKVIEILCKEHDCNLDEVKNVYFTSFIPFLNSLGVVASNGLPEVDVLSKQYDELYLKNKDIDARLFLDHDETLQPDVIACSQLERTPRKNNPDEEVNHVLPQTPVRAAMNTIQQLMMILNSATDKPSDTLIAYFNNCTVNPEDSILKRVESLGHIFKKKFAEAVGQGCAEIGSQRYQLGVRLYYRVMESMLKSEEERLSVHNFSKLLNDNIFHTSLLACALEIVMATYGRTASQSDGTSAETDLSFPWILNVFDLKAFDFYKVIESFIKVEPSLTRDMIKHLERCEHRIMESLAWQSDSPLFDLIKQSKEREGQTDQPEPTSTLNLPLQHNHTAADLYLSPVRSPKKKASGHPQSGTSNPDAQPSATSQTQKPQKSTSLSLFYKKVFRLAYLRLHTLFFRLLSEHPDLEPLIWTLFQHTLQNESELMRDRHLDQIMMCSMYGICKVKNVDLRFKTIVSAYKELPNTNQETFKRVLIREEQYDSIIVFYNLVFMQKLKTNILQYASNRPPTLSPIPHIPRSPYQFSNSPRRVPAGNNIYISPLKSPYKFSDGFHSPTKMTPRSRILVSIGETFGTSEKFQKINQMVCNSESHVKRSAEPSDAPKPLKRLRFDIEGQDEADGGKHLPQESKFQQKLAEMTSTRTRMQKQKLNDGNDTSANEEK", "length": 921, "header": "tr|F1NAY3-1|A0A3Q3AS57_CHICK Computationally mapped isoform of Retinoblastoma-associated protein OS=Gallus gallus OX=9031 GN=RB1 PE=3 SV=3 CANONICAL=A0A3Q3AS57-1" }, "locus": { "chromosome": "1", "start_pos": 168708385, "end_pos": 168633066, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010009040.1", "url": "https://www.ensembl.org/id/ENSGALT00010009040.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010005344.1", "url": "https://www.ensembl.org/id/ENSGALP00010005344.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:386582", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:386582", "resource": "KEGG Pathway" }, { "id": "R-GGA-174178", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-174178", "resource": "Reactome", "description": "APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1" }, { "id": "R-GGA-2299718", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2299718", "resource": "Reactome", "description": "Condensation of Prophase Chromosomes" }, { "id": "R-GGA-2559584", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2559584", "resource": "Reactome", "description": "Formation of Senescence-Associated Heterochromatin Foci (SAHF)" }, { "id": "R-GGA-69200", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-69200", "resource": "Reactome", "description": "Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes" }, { "id": "R-GGA-69202", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-69202", "resource": "Reactome", "description": "Cyclin E associated events during G1/S transition" }, { "id": "R-GGA-69231", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-69231", "resource": "Reactome", "description": "Cyclin D associated events in G1" }, { "id": "R-GGA-69656", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-69656", "resource": "Reactome", "description": "Cyclin A:Cdk2-associated events at S phase entry" }, { "id": "R-GGA-9841922", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9841922", "resource": "Reactome", "description": "MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis" } ], "orthologs": [ { "uniprot_canonical_ac": "F1MD46-1", "protein_name": "Retinoblastoma-associated protein", "gene_name": "RB1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPPKTPRRAAAAAAAAAAEPPPPPLPPPPEEDPEQDSGSEDLPLARLEFEETEEPDFTALCQKLKLPDHVRERAWLTWEKVSSVDGVLEGYVQKKKELWGICIFIAAVDLDEMPFTFTELQKNIETSVYKFFDLLKEIDTSTKVDNAMSRLLKKYNVLCALYSKLERTCELIYLTQPSSSISTEINSMLVLKVSWITFLLAKGQVLQMEDDLVISFQLMLCVLDYFIKLSPPALLKDPYKTAVIPINGSPRTPRRGQNRSARIAKQLENDTRIIEVLCKEHECNIDEVKNVYFKNFIPFMNSLGIVASNGLPEVENLSKQYEEIYLKNKDLDARLFLDHDKTLQADPTDSFEMQRTPRKSNPDEEVNMILPQTPVRTVMNTIQQLMMILNSASDQPSENLISYFNNCTVNPKDSILKRVKDIGDVFKEKFAKAVGQGCMEIGSQRYKLGVRLYYRVMESMLKSEEERLSIQNFSKLLNDNIFHMSLLACALEVVMATYSRSMSQSLDTGTDLSFPWILNVFNLKAFDFYKVIESFIKAEANLTREMIKHLERCEHRIMESLAWLSDSPLFDLIKQAKDREGPVDHFEPACTLNLPLQNNHTAADMYLSPVRSPKKKGPTPRVNSTPNSEAQATSAFQTQKPLKSTSLSLFYKKVYRLAYLRLNTLCARLLSDHPELEHIIWTLFQHTLQNEYELMRDRHLDQIMMCSMYGICKVKNIDLKFKIIVTAYKDLPHAVQETFKRVLIREEEYDSIIVFYNSVFMQRLKTNILQYASTRPPTLSPIPHIPRSPYKFSSSPLRIPGGNIYISPLNNPYKISEGLPTPTKMTPRSRILVSIGESFGTSEKFQKINQMVCNSDRVLKRSAEGSNPPKPLKKLRFDIEGSDEADGSKHLPGESKFQQKLAEMTSTRTRMQKQKMNESVDTSNREEK", "length": 928 }, "evidence": [ { "id": "A0A3Q3AS57", "url": "https://omabrowser.org/oma/group/A0A3Q3AS57/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P06400-1", "protein_name": "Retinoblastoma-associated protein", "gene_name": "RB1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPPKTPRKTAATAAAAAAEPPAPPPPPPPEEDPEQDSGPEDLPLVRLEFEETEEPDFTALCQKLKIPDHVRERAWLTWEKVSSVDGVLGGYIQKKKELWGICIFIAAVDLDEMSFTFTELQKNIEISVHKFFNLLKEIDTSTKVDNAMSRLLKKYDVLFALFSKLERTCELIYLTQPSSSISTEINSALVLKVSWITFLLAKGEVLQMEDDLVISFQLMLCVLDYFIKLSPPMLLKEPYKTAVIPINGSPRTPRRGQNRSARIAKQLENDTRIIEVLCKEHECNIDEVKNVYFKNFIPFMNSLGLVTSNGLPEVENLSKRYEEIYLKNKDLDARLFLDHDKTLQTDSIDSFETQRTPRKSNLDEEVNVIPPHTPVRTVMNTIQQLMMILNSASDQPSENLISYFNNCTVNPKESILKRVKDIGYIFKEKFAKAVGQGCVEIGSQRYKLGVRLYYRVMESMLKSEEERLSIQNFSKLLNDNIFHMSLLACALEVVMATYSRSTSQNLDSGTDLSFPWILNVLNLKAFDFYKVIESFIKAEGNLTREMIKHLERCEHRIMESLAWLSDSPLFDLIKQSKDREGPTDHLESACPLNLPLQNNHTAADMYLSPVRSPKKKGSTTRVNSTANAETQATSAFQTQKPLKSTSLSLFYKKVYRLAYLRLNTLCERLLSEHPELEHIIWTLFQHTLQNEYELMRDRHLDQIMMCSMYGICKVKNIDLKFKIIVTAYKDLPHAVQETFKRVLIKEEEYDSIIVFYNSVFMQRLKTNILQYASTRPPTLSPIPHIPRSPYKFPSSPLRIPGGNIYISPLKSPYKISEGLPTPTKMTPRSRILVSIGESFGTSEKFQKINQMVCNSDRVLKRSAEGSNPPKPLKKLRFDIEGSDEADGSKHLPGESKFQQKLAEMTSTRTRMQKQKMNDSMDTSNKEEK", "length": 928 }, "evidence": [ { "id": "A0A3Q3AS57", "url": "https://omabrowser.org/oma/group/A0A3Q3AS57/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P13405-1", "protein_name": "Retinoblastoma-associated protein", "gene_name": "Rb1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPPKAPRRAAAAEPPPPPPPPPREDDPAQDSGPEELPLARLEFEEIEEPEFIALCQKLKVPDHVRERAWLTWEKVSSVDGILEGYIQKKKELWGICIFIAAVDLDEMPFTFTELQKSIETSVYKFFDLLKEIDTSTKVDNAMSRLLKKYNVLCALYSKLERTCELIYLTQPSSALSTEINSMLVLKISWITFLLAKGEVLQMEDDLVISFQLMLCVVDYFIKFSPPALLREPYKTAAIPINGSPRTPRRGQNRSARIAKQLENDTRIIEVLCKEHECNIDEVKNVYFKNFIPFINSLGIVSSNGLPEVESLSKRYEEVYLKNKDLDARLFLDHDKTLQTDPIDSFETERTPRKNNPDEEANVVTPHTPVRTVMNTIQQLMVILNSASDQPSENLISYFNNCTVNPKENILKRVKDVGHIFKEKFANAVGQGCVDIGVQRYKLGVRLYYRVMESMLKSEEERLSIQNFSKLLNDNIFHMSLLACALEVVMATYSRSTLQHLDSGTDLSFPWILNVLNLKAFDFYKVIESFIKVEANLTREMIKHLERCEHRIMESLAWLSDSPLFDLIKQSKDGEGPDNLEPACPLSLPLQGNHTAADMYLSPLRSPKKRTSTTRVNSAANTETQAASAFHTQKPLKSTSLALFYKKVYRLAYLRLNTLCARLLSDHPELEHIIWTLFQHTLQNEYELMRDRHLDQIMMCSMYGICKVKNIDLKFKIIVTAYKDLPHAAQETFKRVLIREEEFDSIIVFYNSVFMQRLKTNILQYASTRPPTLSPIPHIPRSPYKFSSSPLRIPGGNIYISPLKSPYKISEGLPTPTKMTPRSRILVSIGESFGTSEKFQKINQMVCNSDRVLKRSAEGGNPPKPLKKLRFDIEGADEADGSKHLPAESKFQQKLAEMTSTRTRMQKQRMNESKDVSNKEEK", "length": 921 }, "evidence": [ { "id": "A0A3Q3AS57", "url": "https://omabrowser.org/oma/group/A0A3Q3AS57/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P33568-1", "protein_name": "Retinoblastoma-associated protein", "gene_name": "Rb1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPPKAPRRTAAAEPPPPPPPPPEDDPAQDSDPEELPLIRLEFEKIEEPEFIALCQKLKVPDHVRERAWLTWEKVSSVDGILEGYIQKKKELWGICIFIAAVDLDEMPFTFTELQKSIETSVYKFFDLLKEIDTSTKVDNAVSRLLKKYNVLCALYSKLERTCGLIYLTQPSSGLSTEINSMLVLKVSWITFLLAKGEVVQMEDDLVISFQLMLCVLDYFIKLSPPALLREPYKTAATPINGSPRTPRRGQNRSARIAKQLESDTRTIEVLCKEHECNVDEVKNVYFKNFIPFISSLGIVSSNGLPELESLSKRYEEVYLKSKDLDARLFLDHDKTLQTDTIDSFETERTPRKSNPDEEANMVTPHTPVRTVMNTIQQLMVILNSASDQPSENLISYFSNCTVNPKENILKRVKDVGHIFKEKFASAVGQGCIDIGAQRYKLGVRLYYRVMESMLKSEEERLSIQNFSKLLNDNIFHMSLLACALEVVMATYSRSMLQNLDSGTDLSFPWILNVLNLKAFDFYKVIESFIKVEANLTREMIKHLERCEHRIMESLAWLSDSPLFDLIKQSKDGEGPDHLESACSLSLPLQSNHTAADMYLSPIRSPKKRTSTTRVNSAANTETQAASAFHTQKPLKSTSLSLFYKKVYRLAYLRLNTLCARLLSDHPELEHIIWTLFQHTLENEYELMKDRHLDQIMMCSMYGICKVKNIDLKFKIIVTAYKDLPHAAQETFKRVLIREEEFDSIIVFYNSVFMQRLKTNILQYASTRPPTLSPIPHIPRSPYKFSSSPLRIPGGNIYISPLKSPYKISEGLPTPTKMTPRSRILVSIGESFGTSEKFQKINQMVCNSDRVLKRSAEGGNPPKPLKKLRFDIEGSDEADGSKHLPAESKFQQKLAEMTSTRTRMQKQKLNDSMEISNKEEK", "length": 920 }, "evidence": [ { "id": "A0A3Q3AS57", "url": "https://omabrowser.org/oma/group/A0A3Q3AS57/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 26, "go_terms": [ { "name": "protein localization to chromosome, centromeric region", "id": "GO:0071459", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071459", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q3AS57", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3AS57" } ], "pmid": "" }, { "name": "negative regulation of myofibroblast differentiation", "id": "GO:1904761", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904761", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q3AS57", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3AS57" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q3AS57", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3AS57" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q3AS57", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3AS57" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q3AS57", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3AS57" } ], "pmid": "" }, { "name": "neuron projection development", "id": "GO:0031175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031175", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q3AS57", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3AS57" } ], "pmid": "" }, { "name": "cellular response to insulin stimulus", "id": "GO:0032869", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032869", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q3AS57", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3AS57" } ], "pmid": "" }, { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q3AS57", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3AS57" } ], "pmid": "" }, { "name": "negative regulation of DNA-templated transcription", "id": "GO:0045892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045892", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q3AS57", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3AS57" } ], "pmid": "" }, { "name": "negative regulation of inflammatory response", "id": "GO:0050728", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050728", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q3AS57", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3AS57" } ], "pmid": "" }, { "name": "Ras protein signal transduction", "id": "GO:0007265", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007265", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q3AS57", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3AS57" } ], "pmid": "" }, { "name": "negative regulation of cell growth", "id": "GO:0030308", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030308", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q3AS57", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3AS57" } ], "pmid": "" }, { "name": "positive regulation of mitotic metaphase/anaphase transition", "id": "GO:0045842", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045842", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q3AS57", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3AS57" } ], "pmid": "" }, { "name": "chondrocyte differentiation", "id": "GO:0002062", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002062", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q3AS57", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3AS57" } ], "pmid": "" }, { "name": "negative regulation of G1/S transition of mitotic cell cycle", "id": "GO:2000134", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000134", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q3AS57", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3AS57" } ], "pmid": "" }, { "name": "myoblast differentiation", "id": "GO:0045445", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045445", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q3AS57", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3AS57" } ], "pmid": "" }, { "name": "positive regulation of collagen fibril organization", "id": "GO:1904028", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904028", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q3AS57", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3AS57" } ], "pmid": "" }, { "name": "cell morphogenesis involved in neuron differentiation", "id": "GO:0048667", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048667", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q3AS57", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3AS57" } ], "pmid": "" }, { "name": "heterochromatin formation", "id": "GO:0031507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031507", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q3AS57", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3AS57" } ], "pmid": "" }, { "name": "aortic valve morphogenesis", "id": "GO:0003180", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003180", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q3AS57", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3AS57" } ], "pmid": "" }, { "name": "maintenance of mitotic sister chromatid cohesion", "id": "GO:0034088", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034088", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q3AS57", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3AS57" } ], "pmid": "" }, { "name": "sister chromatid biorientation", "id": "GO:0031134", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031134", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q3AS57", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3AS57" } ], "pmid": "" }, { "name": "negative regulation of cold-induced thermogenesis", "id": "GO:0120163", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120163", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q3AS57", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3AS57" } ], "pmid": "" }, { "name": "developmental process", "id": "GO:0032502", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032502", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q3AS57", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3AS57" } ], "pmid": "" }, { "name": "chromatin organization", "id": "GO:0006325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006325", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q3AS57", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3AS57" } ], "pmid": "" }, { "name": "regulation of cell cycle", "id": "GO:0051726", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051726", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q3AS57", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3AS57" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 9, "go_terms": [ { "name": "importin-alpha family protein binding", "id": "GO:0061676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061676", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q3AS57", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3AS57" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q3AS57", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3AS57" } ], "pmid": "" }, { "name": "ubiquitin protein ligase binding", "id": "GO:0031625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031625", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q3AS57", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3AS57" } ], "pmid": "" }, { "name": "phosphoprotein binding", "id": "GO:0051219", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051219", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q3AS57", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3AS57" } ], "pmid": "" }, { "name": "kinase binding", "id": "GO:0019900", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019900", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q3AS57", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3AS57" } ], "pmid": "" }, { "name": "RNA polymerase II transcription regulatory region sequence-specific DNA binding", "id": "GO:0000977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000977", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q3AS57", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3AS57" } ], "pmid": "" }, { "name": "RNA polymerase II-specific DNA-binding transcription factor binding", "id": "GO:0061629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061629", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q3AS57", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3AS57" } ], "pmid": "" }, { "name": "disordered domain specific binding", "id": "GO:0097718", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097718", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q3AS57", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3AS57" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q3AS57", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3AS57" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q3AS57", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3AS57" } ], "pmid": "" }, { "name": "spindle", "id": "GO:0005819", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005819", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q3AS57", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3AS57" } ], "pmid": "" }, { "name": "PML body", "id": "GO:0016605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016605", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q3AS57", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3AS57" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q3AS57", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3AS57" } ], "pmid": "" }, { "name": "Rb-E2F complex", "id": "GO:0035189", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035189", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q3AS57", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3AS57" } ], "pmid": "" }, { "name": "cyclin/CDK positive transcription elongation factor complex", "id": "GO:0008024", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008024", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q3AS57", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3AS57" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q3AS57", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3AS57" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 237, "end_pos": 239, "annotation": "n_glycosylation_sequon" }, { "start_pos": 396, "end_pos": 398, "annotation": "n_glycosylation_sequon" }, { "start_pos": 462, "end_pos": 464, "annotation": "n_glycosylation_sequon" }, { "start_pos": 591, "end_pos": 593, "annotation": "n_glycosylation_sequon" }, { "start_pos": 682, "end_pos": 684, "annotation": "n_glycosylation_sequon" }, { "start_pos": 913, "end_pos": 915, "annotation": "n_glycosylation_sequon" }, { "start_pos": 921, "end_pos": 923, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A3Q3AS57-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 984, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A3Q3AS57-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A3Q3AS57" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A3Q3AS57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3AS57" }, { "id": "SM00385", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00385" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Cyclin-like", "eco_id": "ECO_0000259", "start_pos": 652, "end_pos": 753, "start_aa": "Leu", "end_aa": "Met", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A3Q3AS57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3AS57" }, { "id": "SM01368", "database": 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"sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A3Q3ATU9-1", "uniprot_ac": "A0A3Q3ATU9", "uniprot_id": "A0A3Q3ATU9_CHICK", "mass": { "chemical_mass": 29337.0, "monoisotopic_mass": 29337.0 }, "refseq": { "ac": "NP_001385123", "name": "protein odd-skipped-related 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001385123" }, "gene_names": [ { "name": "OSR1", "type": "recommended", "evidence": [ { "id": "A0A3Q3ATU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3ATU9" } ] }, { "name": "ODD", "type": "synonym", "evidence": [ { "id": "NP_001385123", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001385123" } ] }, { "name": "OSR1", "type": "synonym", "evidence": [ { "id": "NP_001385123", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001385123" } ] } ], "protein_names": [ { "name": "Protein odd-skipped-related 1", "type": "recommended", "evidence": [ { "id": "A0A3Q3ATU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3ATU9/entry#names_and_taxonomy" } ] }, { "name": "odd-skipped homolog", "type": "synonym", "evidence": [ { "id": "NP_001385123", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001385123" } ] }, { "name": "protein odd-skipped-related 1", "type": "synonym", "evidence": [ { "id": "NP_001385123", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001385123" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR12888502.297230.1, SRR12888493.258138.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992440 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000067.1. On Dec 9, 2021 this sequence version replaced XP_015140433.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001385123", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001385123" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q3ATU9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3ATU9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "OSR1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3ATU9", "locus": { "chromosome": "3", "start_pos": 100776729, "end_pos": 100815111, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010002500", "url": "https://www.ensembl.org/id/ENSGALG00010002500" } ] } } ], "crossref": [ { "id": "A0A3Q3ATU9", "url": "https://alphafold.ebi.ac.uk/entry/A0A3Q3ATU9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000016473", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000016473", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100316920", "url": "https://www.ncbi.nlm.nih.gov/gene/100316920", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050717", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050717", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:100316920", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100316920", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CIFCKEE", "url": 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[ "Protein" ] }, { "id": "NP_001385123", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001385123", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q3ATU9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3ATU9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q3ATU9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3ATU9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BWE8", "url": "https://www.uniprot.org/uniprotkb/E1BWE8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BWE8-1", "url": "https://www.uniprot.org/uniprotkb/E1BWE8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGSKTLPAPVPIHPSLQLTNYSFLQAFNGLPAVPSDHLSNLYGFSALHAVHLHQWTLGYPAMHLPRSSFSKVPSVSSLVDARFQLPTFPLFPHVIQPKQEAANMTLKAKPRFDFANLAVAATQEDHSKLGQVDSQGSPPGLGSLLEVTKLSPEKKPTRGRLPSKTKKEFVCKFCGRHFTKSYNLLIHERTHTDERPYTCDICHKAFRRQDHLRDHRYIHSKEKPFKCQECGKGFCQSRTLAVHKTLHTQVKELKPAKLKC", "length": 260, "header": "tr|A0A3Q3ATU9-1|A0A3Q3ATU9_CHICK Isoform 1 of Protein odd-skipped-related 1 OS=Gallus gallus OX=9031 GN=OSR1 PE=3 SV=1 CANONICAL=A0A3Q3ATU9-1" }, "isoforms": [ { "isoform_ac": "A0A3Q3ATU9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3ATU9/entry#A0A3Q3ATU9-1", "sequence": { "sequence": "MGSKTLPAPVPIHPSLQLTNYSFLQAFNGLPAVPSDHLSNLYGFSALHAVHLHQWTLGYPAMHLPRSSFSKVPSVSSLVDARFQLPTFPLFPHVIQPKQEAANMTLKAKPRFDFANLAVAATQEDHSKLGQVDSQGSPPGLGSLLEVTKLSPEKKPTRGRLPSKTKKEFVCKFCGRHFTKSYNLLIHERTHTDERPYTCDICHKAFRRQDHLRDHRYIHSKEKPFKCQECGKGFCQSRTLAVHKTLHTQVKELKPAKLKC", "length": 260, "header": "tr|A0A3Q3ATU9-1|A0A3Q3ATU9_CHICK Isoform 1 of Protein odd-skipped-related 1 OS=Gallus gallus OX=9031 GN=OSR1 PE=3 SV=1 CANONICAL=A0A3Q3ATU9-1" }, "locus": { "chromosome": "3", "start_pos": 100779179, "end_pos": 100777866, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010005755.1", "url": "https://www.ensembl.org/id/ENSGALT00010005755.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010003576.1", "url": "https://www.ensembl.org/id/ENSGALP00010003576.1" } ] } }, { "isoform_ac": "E1BWE8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3ATU9/entry#E1BWE8-1", "sequence": { "sequence": "MGSKTLPAPVPIHPSLQLTNYSFLQAFNGLPAVPSDHLSNLYGFSALHAVHLHQWTLGYPAMHLPRSSFSKVPSVSSLVDARFQLPTFPLFPHVIQPKQEAANMTLKAKPRFDFANLAVAATQEDHSKLGQVDSQGSPPGLGSLLEVTKLSPEKKPTRGRLPSKTKKEFVCKFCGRHFTKSYNLLIHERTHTDERPYTCDICHKAFRRQDHLRDHRYIHSKEKPFKCQECGKGFCQSRTLAVHKTLHTQEIQRIPEDG", "length": 258, "header": "tr|E1BWE8-1|A0A3Q3ATU9_CHICK Computationally mapped isoform of Protein odd-skipped-related 1 OS=Gallus gallus OX=9031 GN=OSR1 PE=3 SV=2 CANONICAL=A0A3Q3ATU9-1" }, "locus": { "chromosome": "3", "start_pos": 100779179, "end_pos": 100777352, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010005753.1", "url": "https://www.ensembl.org/id/ENSGALT00010005753.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010003574.1", "url": "https://www.ensembl.org/id/ENSGALP00010003574.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:100316920", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100316920", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "B0K011-1", "protein_name": "Protein odd-skipped-related 1", "gene_name": "Osr1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGSKTLPAPVPIHPSLQLTNYSFLQAVNGLPTVPSDHLPNLYGFSALHAVHLHQWTLGYPAMHLPRSSFSKVPGAVSSLMDARFQLPAFPWFPHVIHPKPEITAGGSGAALKTKPRFDFANLALAATQEDPTKLGRGEGPGSPAGGLGALLDVTKLSPEKKPTRGRLPSKTKKEFVCKFCGRHFTKSYNLLIHERTHTDERPYTCDICHKAFRRQDHLRDHRYIHSKEKPFKCQECGKGFCQSRTLAVHKTLHSQVKELKTSKIKC", "length": 266 }, "evidence": [ { "id": "A0A3Q3ATU9", "url": "https://omabrowser.org/oma/group/A0A3Q3ATU9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3HDJ8-1", "protein_name": "Protein odd-skipped-related 1", "gene_name": "Osr1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MGSKTLPAPVPIHPSLQLTNYSFLQAVNGLPTVPSDHLPNLYGFSALHAVHLHQWTLGYPAMHLPRSSFSKVPGAVSSLMDARFQLPAFPWFPHVIHPKPEITTGGSGAALKTKPRFDFANLALAATQEDPSKLGRGEGPGSPAGGLGALLDVTKLSPEKKPTRGRLPSKTKKEFVCKFCGRHFTKSYNLLIHERTHTDERPYTCDICHKAFRRQDHLRDHRYIHSKEKPFKCQECGKGFCQSRTLAVHKTLHSQVKELKTSKIKC", "length": 266 }, "evidence": [ { "id": "A0A3Q3ATU9", "url": "https://omabrowser.org/oma/group/A0A3Q3ATU9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "I3LQZ9-1", "protein_name": "Protein odd-skipped-related 1", "gene_name": "OSR1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGSKTLPAPVPIHPSLQLTNYSFLQAVNGLPTVPSDHLPNLYGFSALHAVHLHQWTLGYPTMHLPRSSFSKVPGAVSSLVDGRFQLPAFPWFPHVIQPKPEITAGGSGPGALKTKPRFDFANLALAATQEDPSKLGRGEGPGSPASGLGALLDVTKLSPEKKPTRGRLPSKTKKEFVCKFCGRHFTKSYNLLIHERTHTDERPYTCDICHKAFRRQDHLRDHRYIHSKEKPFKCQECGKGFCQSRTLAVHKTLHSQVKELKTSKIKC", "length": 267 }, "evidence": [ { "id": "A0A3Q3ATU9", "url": "https://omabrowser.org/oma/group/A0A3Q3ATU9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q08DS3-1", "protein_name": "Protein odd-skipped-related 1", "gene_name": "OSR1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGSKTLPAPVPIHPSLQLTNYSFLQAVNGLPTVPSDHLPNLYGFSALHAVHLHQWTLGYPAMHLPRSSFSKVPGAVSSLVDARFQLPAFPWFPHVIQPKPEITAGGSGPAALKTKPRFDFANLALAATQEDPSKLGRGEGPGSPAGGLGALLDVTKLSPEKKPTRGRLPSKTKKEFVCKFCGRHFTKSYNLLIHERTHTDERPYTCDICHKAFRRQDHLRDHRYIHSKEKPFKCQECGKGFCQSRTLAVHKTLHSQVKELKTSKIKC", "length": 267 }, "evidence": [ { "id": "A0A3Q3ATU9", "url": "https://omabrowser.org/oma/group/A0A3Q3ATU9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8TAX0-1", "protein_name": "Protein odd-skipped-related 1", "gene_name": "OSR1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGSKTLPAPVPIHPSLQLTNYSFLQAVNGLPTVPSDHLPNLYGFSALHAVHLHQWTLGYPAMHLPRSSFSKVPGTVSSLVDARFQLPAFPWFPHVIQPKPEITAGGSVPALKTKPRFDFANLALAATQEDPAKLGRGEGPGSPAGGLGALLDVTKLSPEKKPTRGRLPSKTKKEFVCKFCGRHFTKSYNLLIHERTHTDERPYTCDICHKAFRRQDHLRDHRYIHSKEKPFKCQECGKGFCQSRTLAVHKTLHSQVKELKTSKIKC", "length": 266 }, "evidence": [ { "id": "A0A3Q3ATU9", "url": "https://omabrowser.org/oma/group/A0A3Q3ATU9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9WVG7-1", "protein_name": "Protein odd-skipped-related 1", "gene_name": "Osr1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGSKTLPAPVPIHPSLQLTNYSFLQAVNGLPTVPSDHLPNLYGFSALHAVHLHQWTLGYPAMHLPRSSFSKVPGAVSSLMDARFQLPAFPWFPHVIHPKPEITAGGSGAALKTKPRFDFANLALAATQEDPTKLGRGEGPGSPAGGLGALLDVTKLSPEKKPTRGRLPSKTKKEFVCKFCGRHFTKSYNLLIHERTHTDERPYTCDICHKAFRRQDHLRDHRYIHSKEKPFKCQECGKGFCQSRTLAVHKTLHSQVKELKTSKIKC", "length": 266 }, "evidence": [ { "id": "A0A3Q3ATU9", "url": "https://omabrowser.org/oma/group/A0A3Q3ATU9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 40, "go_terms": [ { "name": "mesonephric duct morphogenesis", "id": "GO:0072180", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072180", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q3ATU9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3ATU9" } ], "pmid": "" }, { "name": "mesangial cell development", "id": "GO:0072143", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072143", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q3ATU9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3ATU9" } ], "pmid": "" }, { "name": "metanephric mesenchymal cell differentiation", "id": "GO:0072162", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072162", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q3ATU9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3ATU9" } ], "pmid": "" }, { "name": "specification of anterior mesonephric tubule identity", "id": "GO:0072168", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072168", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q3ATU9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3ATU9" } ], "pmid": "" }, { "name": "specification of posterior mesonephric tubule identity", "id": "GO:0072169", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072169", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q3ATU9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3ATU9" } ], "pmid": "" }, { "name": "negative regulation of nephron tubule epithelial cell differentiation", "id": "GO:0072183", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072183", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q3ATU9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3ATU9" } ], "pmid": "" }, { "name": "renal vesicle progenitor cell differentiation", "id": "GO:0072184", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072184", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q3ATU9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3ATU9" } ], "pmid": "" }, { "name": "ureter urothelium development", "id": "GO:0072190", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072190", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q3ATU9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3ATU9" } ], "pmid": "" }, { "name": "metanephric smooth muscle tissue development", "id": "GO:0072208", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072208", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q3ATU9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3ATU9" } ], "pmid": "" }, { "name": "metanephric nephron tubule development", "id": "GO:0072234", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072234", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q3ATU9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3ATU9" } ], "pmid": "" }, { "name": "metanephric interstitial fibroblast development", "id": "GO:0072259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072259", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q3ATU9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3ATU9" } ], "pmid": "" }, { "name": "pattern specification involved in metanephros development", "id": "GO:0072268", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072268", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q3ATU9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3ATU9" } ], "pmid": "" }, { "name": "metanephric cap mesenchymal cell proliferation involved in metanephros development", "id": "GO:0090094", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090094", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q3ATU9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3ATU9" } ], "pmid": "" }, { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q3ATU9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3ATU9" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q3ATU9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3ATU9" } ], "pmid": "" }, { "name": "positive regulation of gene expression", "id": "GO:0010628", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010628", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q3ATU9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3ATU9" } ], "pmid": "" }, { "name": "negative regulation of apoptotic process", "id": "GO:0043066", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043066", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q3ATU9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3ATU9" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q3ATU9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3ATU9" } ], "pmid": "" }, { "name": "stem cell differentiation", "id": "GO:0048863", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048863", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q3ATU9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3ATU9" } ], "pmid": "" }, { "name": "cellular response to retinoic acid", "id": "GO:0071300", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071300", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q3ATU9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3ATU9" } ], "pmid": "" }, { "name": "urogenital system development", "id": "GO:0001655", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001655", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q3ATU9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3ATU9" } ], "pmid": "" }, { "name": "embryonic forelimb morphogenesis", "id": "GO:0035115", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035115", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q3ATU9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3ATU9" } ], "pmid": "" }, { "name": "positive regulation of bone mineralization", "id": "GO:0030501", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030501", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q3ATU9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3ATU9" } ], "pmid": "" }, { "name": "roof of mouth development", "id": "GO:0060021", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060021", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q3ATU9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3ATU9" } ], "pmid": "" }, { "name": "embryonic hindlimb morphogenesis", "id": "GO:0035116", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035116", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q3ATU9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3ATU9" } ], "pmid": "" }, { "name": "chondrocyte differentiation", "id": "GO:0002062", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002062", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q3ATU9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3ATU9" } ], "pmid": "" }, { "name": "sodium ion transmembrane transport", "id": "GO:0035725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035725", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q3ATU9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3ATU9" } ], "pmid": "" }, { "name": "middle ear morphogenesis", "id": "GO:0042474", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042474", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q3ATU9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3ATU9" } ], "pmid": "" }, { "name": "embryonic digit morphogenesis", "id": "GO:0042733", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042733", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q3ATU9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3ATU9" } ], "pmid": "" }, { "name": "pattern specification process", "id": "GO:0007389", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007389", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q3ATU9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3ATU9" } ], "pmid": "" }, { "name": "positive regulation of epithelial cell proliferation", "id": "GO:0050679", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050679", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q3ATU9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3ATU9" } ], "pmid": "" }, { "name": "metanephric glomerulus vasculature development", "id": "GO:0072239", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072239", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q3ATU9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3ATU9" } ], "pmid": "" }, { "name": "ureteric bud development", "id": "GO:0001657", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001657", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q3ATU9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3ATU9" } ], "pmid": "" }, { "name": "embryonic skeletal limb joint morphogenesis", "id": "GO:0036023", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036023", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q3ATU9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3ATU9" } ], "pmid": "" }, { "name": "pronephros development", "id": "GO:0048793", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048793", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q3ATU9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3ATU9" } ], "pmid": "" }, { "name": "negative regulation of sodium ion transmembrane transport", "id": "GO:1902306", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902306", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q3ATU9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3ATU9" } ], "pmid": "" }, { "name": "positive regulation of gastrulation", "id": "GO:2000543", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000543", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q3ATU9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3ATU9" } ], "pmid": "" }, { "name": "somitogenesis", "id": "GO:0001756", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001756", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q3ATU9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3ATU9" } ], "pmid": "" }, { "name": "nephrogenic mesenchyme development", "id": "GO:0072076", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072076", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q3ATU9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3ATU9" } ], "pmid": "" }, { "name": "negative regulation of mesonephric nephron tubule epithelial cell differentiation", "id": "GO:2000094", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000094", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q3ATU9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3ATU9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q3ATU9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3ATU9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q3ATU9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3ATU9" } ], "pmid": "" }, { "name": "RNA polymerase II transcription regulatory region sequence-specific DNA binding", "id": "GO:0000977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000977", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q3ATU9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3ATU9" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q3ATU9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3ATU9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 103, "end_pos": 105, "annotation": "n_glycosylation_sequon" }, { "start_pos": 20, "end_pos": 22, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A3Q3ATU9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 260, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A3Q3ATU9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A3Q3ATU9" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A3Q3ATU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3ATU9" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 169, "end_pos": 196, "start_aa": "Phe", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 103, "end_pos": 105 }, { "start_pos": 20, "end_pos": 22 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", 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}, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A3S5ZPN3-1", "uniprot_ac": "A0A3S5ZPN3", "uniprot_id": "A0A3S5ZPN3_CHICK", "mass": { "chemical_mass": 67673.0, "monoisotopic_mass": 67673.0 }, "refseq": { "ac": "XP_015135357", "name": "probable ATP-dependent RNA helicase DDX5 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015135357" }, "gene_names": [ { "name": "DDX5", "type": "recommended", "evidence": [ { "id": "A0A3S5ZPN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPN3" } ] }, { "name": "DDX5", "type": "synonym", "evidence": [ { "id": "XP_015135357", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015135357" } ] } ], "protein_names": [ { "name": "Probable ATP-dependent RNA helicase DDX5", "type": "recommended", "evidence": [ { "id": "A0A3S5ZPN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPN3/entry#names_and_taxonomy" } ] }, { "name": "3.6.4.13", "type": "synonym", "evidence": [ { "id": "A0A3S5ZPN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPN3/entry#names_and_taxonomy" } ] }, { "name": "DEAD box protein 5", "type": "synonym", "evidence": [ { "id": "A0A3S5ZPN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPN3/entry#names_and_taxonomy" } ] }, { "name": "probable ATP-dependent RNA helicase DDX5 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015135357", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015135357" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052549.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015135357", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015135357" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A3S5ZPN3", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPN3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "DDX5", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPN3", "locus": { "chromosome": "18", "start_pos": 7518835, "end_pos": 7526490, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029634", "url": "https://www.ensembl.org/id/ENSGALG00010029634" } ] } } ], "crossref": [ { "id": "A0A3S5ZPN3", "url": "https://alphafold.ebi.ac.uk/entry/A0A3S5ZPN3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000003532", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000003532", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd18049", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18049", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18787", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18787", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "395629", "url": "https://www.ncbi.nlm.nih.gov/gene/395629", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000629", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000629", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001650", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001650", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011545", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011545", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012587", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012587", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014001", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014001", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014014", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014014", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "STMPKFE", "url": "https://omabrowser.org/oma/group/STMPKFE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3S5ZPN3", "url": "https://www.orthodb.org/?gene=A0A3S5ZPN3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1APK2", "url": "https://www.orthodb.org/?gene=A0A8V1APK2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47958", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47958", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00270", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00270", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00271", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00271", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08061", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08061", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-3899300", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3899300", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-72163", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72163", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9018519", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9018519", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9770562", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9770562", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015135357", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015135357", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "13065", "url": "https://www.rhea-db.org/rhea/13065", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3S5ZPN3", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPN3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3S5ZPN3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPN3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1APK2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APK2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1APK2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APK2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPGYSSDRDRGFGAPRFGGSRAGPLSGKKFGNPGEKLTKKKWNLDELPKFEKNFYQEHPDVVRRTAQEVEQYRSSKEVTVRGHNCPKPIINFYEANFPANVMEVIQRQNFTEPTAIQAQGWPVALSGLDMVGVAQTGSGKTLSYLLPAIVHINHQPFLERGDGPICLVLAPTRELAQQVQQVAAEYSRACRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLEAGKTNLRRCTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAEDFLKEYVHINIGALELSANHNILQIVDVCHDVEKDDKLIRLMEEIMSEKENKTIVFVETKRRCDDLTRKMRRDGWPAMGIHGDKSQQERDWVLNEFKHGKAPILIATDVASRGLDVEDVKFVINYDYPNSSEDYIHRIGRTARSTKTGTAYTFFTPNNIKQVNDLISVLREANQAINPKLLQLIEDRGSGRSRGDRRDRYSAGKRGGFSSFRERENFERTYGALGKRDFGAKAQNGAYSTQSFSNGTPFGNGFAAAGMQAGFRAGNPAGAYQNGYDQQYGSNIANMHNGMNQQQYAYPATGAAPMIGYPMPASYSQ", "length": 603, "header": "tr|A0A3S5ZPN3-1|A0A3S5ZPN3_CHICK Isoform 1 of Probable ATP-dependent RNA helicase DDX5 OS=Gallus gallus OX=9031 GN=DDX5 PE=1 SV=1 CANONICAL=A0A3S5ZPN3-1" }, "isoforms": [ { "isoform_ac": "A0A3S5ZPN3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPN3/entry#A0A3S5ZPN3-1", "sequence": { "sequence": "MPGYSSDRDRGFGAPRFGGSRAGPLSGKKFGNPGEKLTKKKWNLDELPKFEKNFYQEHPDVVRRTAQEVEQYRSSKEVTVRGHNCPKPIINFYEANFPANVMEVIQRQNFTEPTAIQAQGWPVALSGLDMVGVAQTGSGKTLSYLLPAIVHINHQPFLERGDGPICLVLAPTRELAQQVQQVAAEYSRACRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLEAGKTNLRRCTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAEDFLKEYVHINIGALELSANHNILQIVDVCHDVEKDDKLIRLMEEIMSEKENKTIVFVETKRRCDDLTRKMRRDGWPAMGIHGDKSQQERDWVLNEFKHGKAPILIATDVASRGLDVEDVKFVINYDYPNSSEDYIHRIGRTARSTKTGTAYTFFTPNNIKQVNDLISVLREANQAINPKLLQLIEDRGSGRSRGDRRDRYSAGKRGGFSSFRERENFERTYGALGKRDFGAKAQNGAYSTQSFSNGTPFGNGFAAAGMQAGFRAGNPAGAYQNGYDQQYGSNIANMHNGMNQQQYAYPATGAAPMIGYPMPASYSQ", "length": 603, "header": "tr|A0A3S5ZPN3-1|A0A3S5ZPN3_CHICK Isoform 1 of Probable ATP-dependent RNA helicase DDX5 OS=Gallus gallus OX=9031 GN=DDX5 PE=1 SV=1 CANONICAL=A0A3S5ZPN3-1" }, "locus": { "chromosome": "18", "start_pos": 7526217, "end_pos": 7519664, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071653.1", "url": "https://www.ensembl.org/id/ENSGALT00010071653.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044343.1", "url": "https://www.ensembl.org/id/ENSGALP00010044343.1" } ] } }, { "isoform_ac": "A0A8V1APK2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPN3/entry#A0A8V1APK2-1", "sequence": { "sequence": "VPGSRFGAPRFGGSRAGPLSGKKFGNPGEKLTKKKWNLDELPKFEKNFYQEHPDVVRRTAQEVEQYRSSKEVTVRGHNCPKPIINFYEANFPANVMEVIQRQNFTEPTAIQAQGWPVALSGLDMVGVAQTGSGKTLSYLLPAIVHINHQPFLERGDGPICLVLAPTRELAQQVQQVAAEYSRACRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLEAGKTNLRRCTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAEDFLKEYVHINIGALELSANHNILQIVDVCHDVEKDDKLIRLMEEIMSEKENKTIVFVETKRRCDDLTRKMRRDGWPAMGIHGDKSQQERDWVLNEFKHGKAPILIATDVASRGLDVEDVKFVINYDYPNSSEDYIHRIGRTARSTKTGTAYTFFTPNNIKQVNDLISVLREANQAINPKLLQLIEDRGSGRSRGDRRDRYSAGKRGGFSSFRERENFERTYGALGKRDFGAKAQNGAYSTQSFSNGTPFGNGFAAAGMQAGFRAGNPAGAYQNGYDQQYGSNIANMHNGMNQQQYAYPATGAAPMIGYPMPASYSQ", "length": 597, "header": "tr|A0A8V1APK2-1|A0A3S5ZPN3_CHICK Computationally mapped isoform of Probable ATP-dependent RNA helicase DDX5 OS=Gallus gallus OX=9031 GN=DDX5 PE=1 SV=1 CANONICAL=A0A3S5ZPN3-1" }, "locus": { "chromosome": "18", "start_pos": 7525363, "end_pos": 7519664, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071652.1", "url": "https://www.ensembl.org/id/ENSGALT00010071652.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044342.1", "url": "https://www.ensembl.org/id/ENSGALP00010044342.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-GGA-3899300", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3899300", "resource": "Reactome", "description": "SUMOylation of transcription cofactors" }, { "id": "R-GGA-72163", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72163", "resource": "Reactome", "description": "mRNA Splicing - Major Pathway" }, { "id": "R-GGA-9018519", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9018519", "resource": "Reactome", "description": "Estrogen-dependent gene expression" }, { "id": "R-GGA-9770562", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9770562", "resource": "Reactome", "description": "mRNA Polyadenylation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1M155-1", "protein_name": "Probable ATP-dependent RNA helicase DDX5", "gene_name": "DDX5", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSGYSSDRDRGRDRGFGAPRFGGSRAGPLSGKKFGNPGEKLVKKKWNLDELPKFEKNFYQEHPDLARRTAQEVETYRRSKEITVRGHNCPKPVLNFYEANFPANVMDVIARQNFTEPTAIQAQGWPVALSGLDMVGVAQTGSGKTLSYLLPAIVHINHQPFLERGDGPICLVLAPTRELAQQVQQVAAEYCRACRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLECGKTNLRRTTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAEDFLKDYIHINIGALELSANHNILQIVDVCHDVEKDEKLIRLMEEIMSEKENKTIVFVETKRRCDELTRKMRRDGWPAMGIHGDKSQQERDWVLNEFKHGKAPILIATDVASRGLDVEDVKFVINYDYPNSSEDYIHRIGRTARSTKTGTAYTFFTPNNIKQVSDLISVLREANQAINPKLLQLVEDRGSGRSRGRGGMKDDRRDRYSAGKRGGFNTFRDRENYDRGYSSLLKRDFGAKTQNGVYSAANYTNGSFGSNFVSAGIQTSFRTGNPTGTYQNGYDSTQQYGSNVPNMHNGMNQQAYAYPATAAAPMIGYPMPTGYSQ", "length": 614 }, "evidence": [ { "id": "A0A3S5ZPN3", "url": "https://omabrowser.org/oma/group/A0A3S5ZPN3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3HCT4-1", "protein_name": "Probable ATP-dependent RNA helicase DDX5", "gene_name": "Ddx5", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSSYSSDRDRGRDRGFGAPRFGGSRTGPLSGKKFGNPGEKLVKKKWNLDELPKFEKNFYQEHPDLARRTAQEVDTYRRSKEITVRGHNCPKPVLNFYEANFPANVMDVIARQNFTEPTAIQAQGWPVALSGLDMVGVAQTGSGKTLSYLLPAIVHINHQPFLERGDGPICLVLAPTRELAQQVQQVAAEYCRACRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLECGKTNLRRTTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAEDFLKDYIHINIGALELSANHNILQIVDVCHDVEKDEKLIRLMEEIMSEKENKTIVFVETKRRCDELTRKMRRDGWPAMGIHGDKSQQERDWVLNEFKHGKAPILIATDVASRGLDVEDVKFVINYDYPNSSEDYIHRIGRTARSTKTGTAYTFFTPNNIKQVSDLISVLREANQAINPKLLQLVEDRGSGRSRGRGGMKDDRRDRYSAGKRGGFNTFRDRENYDRGYSSLLKRDFGAKTQNGVYSAANYTNGSFGSNFVSAGIQTSFRTGNPTGTYQNGYDSTQQYGSNVANMHNGMNQQAYAYPATAAAAPMIGYPMPTGYSQ", "length": 615 }, "evidence": [ { "id": "A0A3S5ZPN3", "url": "https://omabrowser.org/oma/group/A0A3S5ZPN3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P24783-1", "protein_name": "ATP-dependent RNA helicase DBP2", "gene_name": "DBP2", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MTYGGRDQQYNKTNYKSRGGDFRGGRNSDRNSYNDRPQGGNYRGGFGGRSNYNQPQELIKPNWDEELPKLPTFEKNFYVEHESVRDRSDSEIAQFRKENEMTISGHDIPKPITTFDEAGFPDYVLNEVKAEGFDKPTGIQCQGWPMALSGRDMVGIAATGSGKTLSYCLPGIVHINAQPLLAPGDGPIVLVLAPTRELAVQIQTECSKFGHSSRIRNTCVYGGVPKSQQIRDLSRGSEIVIATPGRLIDMLEIGKTNLKRVTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVKQLAADYLNDPIQVQVGSLELSASHNITQIVEVVSDFEKRDRLNKYLETASQDNEYKTLIFASTKRMCDDITKYLREDGWPALAIHGDKDQRERDWVLQEFRNGRSPIMVATDVAARGIDVKGINYVINYDMPGNIEDYVHRIGRTGRAGATGTAISFFTEQNKGLGAKLISIMREANQNIPPELLKYDRRSYGGGHPRYGGGRGGRGGYGRRGGYGGGRGGYGGNRQRDGGWGNRGRSNY", "length": 546 }, "evidence": [ { "id": "A0A3S5ZPN3", "url": "https://omabrowser.org/oma/group/A0A3S5ZPN3/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q61656-1", "protein_name": "Probable ATP-dependent RNA helicase DDX5", "gene_name": "Ddx5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSYSSDRDRGRDRGFGAPRFGGSRTGPLSGKKFGNPGEKLVKKKWNLDELPKFEKNFYQEHPDLARRTAQEVDTYRRSKEITVRGHNCPKPVLNFYEANFPANVMDVIARQNFTEPTAIQAQGWPVALSGLDMVGVAQTGSGKTLSYLLPAIVHINHQPFLERGDGPICLVLAPTRELAQQVQQVAAEYCRACRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLECGKTNLRRTTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAEDFLKDYIHINIGALELSANHNILQIVDVCHDVEKDEKLIRLMEEIMSEKENKTIVFVETKRRCDELTRKMRRDGWPAMGIHGDKSQQERDWVLNEFKHGKAPILIATDVASRGLDVEDVKFVINYDYPNSSEDYIHRIGRTARSTKTGTAYTFFTPNNIKQVSDLISVLREANQAINPKLLQLVEDRGSGRSRGRGGMKDDRRDRYSAGKRGGFNTFRDRENYDRGYSNLLKRDFGAKTQNGVYSAANYTNGSFGSNFVSAGIQTSFRTGNPTGTYQNGYDSTQQYGSNVANMHNGMNQQAYAYPLPQAAPMIGYPMPTGYSQ", "length": 614 }, "evidence": [ { "id": "A0A3S5ZPN3", "url": "https://omabrowser.org/oma/group/A0A3S5ZPN3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9C718-1", "protein_name": "DEAD-box ATP-dependent RNA helicase 20", "gene_name": "RH20", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSRYDSRTGDSTSYRDRRSDSGFGGTSSYGSSGSHTSSKKDNDGNESPRKLDLDGLTPFEKNFYVESPAVAAMTDTEVEEYRKLREITVEGKDIPKPVKSFRDVGFPDYVLEEVKKAGFTEPTPIQSQGWPMAMKGRDLIGIAETGSGKTLSYLLPAIVHVNAQPMLAHGDGPIVLVLAPTRELAVQIQQEASKFGSSSKIKTTCIYGGVPKGPQVRDLQKGVEIVIATPGRLIDMMESNNTNLRRVTYLVLDEADRMLDMGFDPQIRKIVSHIRPDRQTLYWSATWPKEVEQLSKKFLYNPYKVIIGSSDLKANRAIRQIVDVISESQKYNKLVKLLEDIMDGSRILVFLDTKKGCDQITRQLRMDGWPALSIHGDKSQAERDWVLSEFRSGKSPIMTATDVAARGLDVKDVKYVINYDFPGSLEDYVHRIGRTGRAGAKGTAYTFFTVANARFAKELTNILQEAGQKVSPELASMGRSTAPPPPGLGGFRDRGSRRGWS", "length": 501 }, "evidence": [ { "id": "A0A3S5ZPN3", "url": "https://omabrowser.org/oma/group/A0A3S5ZPN3/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 12, "go_terms": [ { "name": "pre-mRNA binding", "id": "GO:0036002", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036002", "evidence": [ { "database": "UniProtKB", "id": "A0A3S5ZPN3", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPN3" } ], "pmid": "" }, { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "A0A3S5ZPN3", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPN3" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A3S5ZPN3", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPN3" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "A0A3S5ZPN3", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPN3" } ], "pmid": "" }, { "name": "ribonucleoprotein complex binding", "id": "GO:0043021", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043021", "evidence": [ { "database": "UniProtKB", "id": "A0A3S5ZPN3", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPN3" } ], "pmid": "" }, { "name": "mRNA 3'-UTR binding", "id": "GO:0003730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003730", "evidence": [ { "database": "UniProtKB", "id": "A0A3S5ZPN3", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPN3" } ], "pmid": "" }, { "name": "nuclear androgen receptor binding", "id": "GO:0050681", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050681", "evidence": [ { "database": "UniProtKB", "id": "A0A3S5ZPN3", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPN3" } ], "pmid": "" }, { "name": "R-SMAD binding", "id": "GO:0070412", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070412", "evidence": [ { "database": "UniProtKB", "id": "A0A3S5ZPN3", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPN3" } ], "pmid": "" }, { "name": "MH2 domain binding", "id": "GO:0035500", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035500", "evidence": [ { "database": "UniProtKB", "id": "A0A3S5ZPN3", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPN3" } ], "pmid": "" }, { "name": "primary miRNA binding", "id": "GO:0070878", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070878", "evidence": [ { "database": "UniProtKB", "id": "A0A3S5ZPN3", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPN3" } ], "pmid": "" }, { "name": "RNA helicase activity", "id": "GO:0003724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003724", "evidence": [ { "database": "UniProtKB", "id": "A0A3S5ZPN3", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPN3" } ], "pmid": "" }, { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A3S5ZPN3", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPN3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 17, "go_terms": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "A0A3S5ZPN3", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPN3" } ], "pmid": "" }, { "name": "BMP signaling pathway", "id": "GO:0030509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030509", "evidence": [ { "database": "UniProtKB", "id": "A0A3S5ZPN3", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPN3" } ], "pmid": "" }, { "name": "rhythmic process", "id": "GO:0048511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048511", "evidence": [ { "database": "UniProtKB", "id": "A0A3S5ZPN3", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPN3" } ], "pmid": "" }, { "name": "positive regulation of DNA damage response, signal transduction by p53 class mediator", "id": "GO:0043517", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043517", "evidence": [ { "database": "UniProtKB", "id": "A0A3S5ZPN3", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPN3" } ], "pmid": "" }, { "name": "intrinsic apoptotic signaling pathway by p53 class mediator", "id": "GO:0072332", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072332", "evidence": [ { "database": "UniProtKB", "id": "A0A3S5ZPN3", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPN3" } ], "pmid": "" }, { "name": "epithelial to mesenchymal transition", "id": "GO:0001837", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001837", "evidence": [ { "database": "UniProtKB", "id": "A0A3S5ZPN3", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPN3" } ], "pmid": "" }, { "name": "androgen receptor signaling pathway", "id": "GO:0030521", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030521", "evidence": [ { "database": "UniProtKB", "id": "A0A3S5ZPN3", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPN3" } ], "pmid": "" }, { "name": "nuclear-transcribed mRNA catabolic process", "id": "GO:0000956", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000956", "evidence": [ { "database": "UniProtKB", "id": "A0A3S5ZPN3", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPN3" } ], "pmid": "" }, { "name": "regulation of androgen receptor signaling pathway", "id": "GO:0060765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060765", "evidence": [ { "database": "UniProtKB", "id": "A0A3S5ZPN3", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPN3" } ], "pmid": "" }, { "name": "estrogen receptor signaling pathway", "id": "GO:0030520", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030520", "evidence": [ { "database": "UniProtKB", "id": "A0A3S5ZPN3", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPN3" } ], "pmid": "" }, { "name": "mRNA transcription", "id": "GO:0009299", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009299", "evidence": [ { "database": "UniProtKB", "id": "A0A3S5ZPN3", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPN3" } ], "pmid": "" }, { "name": "primary miRNA processing", "id": "GO:0031053", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031053", "evidence": [ { "database": "UniProtKB", "id": "A0A3S5ZPN3", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPN3" } ], "pmid": "" }, { "name": "alternative mRNA splicing, via spliceosome", "id": "GO:0000380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000380", "evidence": [ { "database": "UniProtKB", "id": "A0A3S5ZPN3", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPN3" } ], "pmid": "" }, { "name": "regulation of alternative mRNA splicing, via spliceosome", "id": "GO:0000381", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000381", "evidence": [ { "database": "UniProtKB", "id": "A0A3S5ZPN3", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPN3" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A3S5ZPN3", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPN3" } ], "pmid": "" }, { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "A0A3S5ZPN3", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPN3" } ], "pmid": "" }, { "name": "RNA splicing", "id": "GO:0008380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008380", "evidence": [ { "database": "UniProtKB", "id": "A0A3S5ZPN3", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPN3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A3S5ZPN3", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPN3" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A3S5ZPN3", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPN3" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A3S5ZPN3", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPN3" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "A0A3S5ZPN3", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPN3" } ], "pmid": "" }, { "name": "catalytic step 2 spliceosome", "id": "GO:0071013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071013", "evidence": [ { "database": "UniProtKB", "id": "A0A3S5ZPN3", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPN3" } ], "pmid": "" }, { "name": "ribonucleoprotein complex", "id": "GO:1990904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990904", "evidence": [ { "database": "UniProtKB", "id": "A0A3S5ZPN3", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPN3" } ], "pmid": "" }, { "name": "spliceosomal complex", "id": "GO:0005681", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005681", "evidence": [ { "database": "UniProtKB", "id": "A0A3S5ZPN3", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPN3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 109, "end_pos": 111, "annotation": "n_glycosylation_sequon" }, { "start_pos": 338, "end_pos": 340, "annotation": "n_glycosylation_sequon" }, { "start_pos": 416, "end_pos": 418, "annotation": "n_glycosylation_sequon" }, { "start_pos": 532, "end_pos": 534, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "13065", "name": "", "equation": "ATP + H2O = ADP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZC95-1", "A0A1D5PHB6-1", "A0A8V0XJV9-1", "A0A8V0ZFN9-1", "A0A1D5PIN7-1", "A0A8V0XT73-1", "A0A8V0XZB8-1", "A0A8V1AJ43-1", "A0A8V0ZU49-1", "P53478-1", "Q5F485-1", "Q5ZHZ0-1", "Q5ZI74-1", "Q5ZIW1-1", "Q5ZKB9-1", "Q5ZM36-1", "Q5ZMN2-1", "A0A8V0XLC7-1", "F1NFJ0-1", "A0A8V0YT68-1", "A0A1D5NTY5-1", "A0A8V0YU49-1", "A0A8V0YHC8-1", "A0A8V0ZPN6-1", "Q5ZJF6-1", "Q5ZKB7-1", "Q8JFP1-1", "A0A8V0YUW3-1", "Q5ZLN8-1", "E1BY42-1", "F1N8Z4-1", "F1NHI3-1", "A0A8V0XI26-1", "A0A8V0XEC4-1", "A0A8V0Y1J8-1", "A0A8V0Y242-1", "A0A8V0X9Z6-1", "A0A8V0Z289-1", "A0A8V0YFB8-1", "A0A8V0YFG2-1", "A0A8V0YNF9-1", "F1N991-1", "A0A8V0ZZF5-1", "A0A8V1ACD8-1", "A0A8V0ZUT3-1", "A0A8V0ZNU6-1", "A0A1D5P5I0-1", "A0A8V0ZZK3-1", "A0A8V1A3M1-1", "A0A8V1AJY9-1", "A0A8V1A712-1", "A0A8V1A7M6-1", "A0A3S5ZPN3-1", "A0A8V1A4V3-1", "A0A8V1AER6-1", "A0A8V1AL41-1", "A0A8V1A5D6-1", "A0A1D5PRR9-1", "A0A8V0Y0A4-1", "Q5ZKK7-1", "A0A8V1AFG8-1", "A0A8V0ZWH7-1", "A0A8V0YLM0-1", "A0A8V0ZNW3-1", "F1ND48-1", "F1NQJ3-1", "P08023-1", "P60706-1", "P63270-1", "P68034-1", "P68139-1", "Q5ZJT0-1", "Q5ZMQ2-1", "Q90593-1", "Q92058-1", "Q9I920-1", "Q90WU3-1", "A0A8V0ZVY2-1", "A0A8V0ZPM1-1", "Q3YK19-1", "E1BSC0-1", "A0A8V0X9Y7-1", "Q5ZM98-1", "F1NZ23-1", "A0A8V0YUG9-1", "F1NN44-1", "P08110-1", "F1NTD6-1", "A0A8V0Z655-1", "A0A8V1ALH0-1", "B6ZLK2-1", "A0A8V0YLC1-1", "Q06A37-1", "A0A8V0YGQ1-1", "A0A1D5PD32-1", "Q6EE31-1", "A0A8V0XX13-1", "A0A8V0YCY8-1", "A0A8V0Z5P2-1", "A0A8V0ZUQ0-1", "A0A8V1ADZ7-1", "A0A8V0XG98-1", "A0A8V0ZR10-1", "A0A8V1AFJ9-1", "Q5ZJ54-1", "Q5ZJK8-1", "A0A8V0Y005-1", "A0A8V0YAA4-1", "A0A8V0XGV3-1", "A0A8V0X600-1", "Q5ZM73-1", "Q5ZM83-1", "A0A8V0ZUR5-1", "A0A8V0ZE45-1", "A0A8V0ZEN5-1", "F1NA92-1", "A0A8V0ZTR5-1", "A0A8V1A7P4-1", "A0A8V1AIK2-1", "F1P5C0-1", "A0A8V0XHD1-1", "A0A8V0X655-1", "A0A8V0XMP8-1", "A0A8V0YUC5-1", "A0A8V0Z1F9-1", "A0A8V0Z659-1", "A0A8V0YRH6-1", "A0A8V0ZS56-1", "I0IUP3-1", "I0IUP4-1", "O93257-1", "O93295-1", "A0A8V0ZIP8-1", "Q9DG67-1", "P37383-1", "Q5ZKG3-1", "P79784-1", "A0A1D5PS27-1", "A0A1D5PVS9-1", "A0A8V1AE46-1", "A0A8V1A8Y2-1", "A0A8V1AKU6-1", "O12944-1", "A0A8V0YQS3-1", "A0A8V0Z2M8-1" ], "evidence": [ { "id": "13065", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/13065" } ] }, { "id": "R-GGA-3900177", "name": "SUMOylation of DDX5 with SUMO1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [ "R-GGA-3900136" ], "output_participant_list": [ "R-GGA-3900041" ], "enzyme_list": [ "A0A3S5ZPN3-1", "P63283-1" ], "evidence": [ { "id": "R-GGA-3900177", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3900177" } ] }, { "id": "R-GGA-3900194", "name": "PIAS1 SUMOylates DDX5 with SUMO2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [ "R-GGA-3900186" ], "enzyme_list": [ "A0A3S5ZPN3-1", "P63283-1" ], "evidence": [ { "id": "R-GGA-3900194", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3900194" } ] }, { "id": "R-GGA-9009533", "name": "TBP and TFIIA bind TATA box on ESR1:estrogen bound TFF1 gene promoter", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3S5ZPN3-1" ], "evidence": [ { "id": "R-GGA-9009533", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9009533" } ] }, { "id": "R-GGA-9009536", "name": "DDX5 binds ESR1:estrogen:TFF1 gene promoter", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3S5ZPN3-1" ], "evidence": [ { "id": "R-GGA-9009536", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9009536" } ] }, { "id": "R-GGA-9023860", "name": "Histone acetyltransferases are recruited to the TFF1 gene", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0X4Y2-1", "A0A8V0X6X9-1", "A0A8V0YJ98-1", "A0A3S5ZPN3-1" ], "evidence": [ { "id": "R-GGA-9023860", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9023860" } ] }, { "id": "R-GGA-9794542", "name": "Formation of the Spliceosomal C complex containing intron lariat", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1NCB0-1", "A0A8V0XUB5-1", "E1BSC0-1", "A0A8V0YUC5-1", "A0A1D5PZS0-1", "Q5ZM36-1", "A0A1D5PW44-1", "Q5ZLV2-1", "F1NAJ2-1", "A0A8V0ZS62-1", "A0A8V0ZU13-1", "F1NHI3-1", "A0A8V0Z3A2-1", "A0A8V0XHD1-1", "A0A8V0ZWH7-1", "A0A3S5ZPN3-1" ], "evidence": [ { "id": "R-GGA-9794542", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9794542" } ] }, { "id": "R-GGA-9970141", "name": "Core CPA complex binds capped pre-mRNA", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1NCB0-1", "E1BSC0-1", "F1NHI3-1", "A0A8V0ZE45-1", "A0A3S5ZPN3-1" ], "evidence": [ { "id": "R-GGA-9970141", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9970141" } ] }, { "id": "R-GGA-9970190", "name": "PP1 dephosphorylates RNA Pol II", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1NCB0-1", "E1BSC0-1", "A0A8V0YVP3-1", "Q5ZJL4-1", "A0A8V0ZWA8-1", "A0A8V0YUZ1-1", "F1NHI3-1", "A0A8V0Z2C0-1", "A0A8V0ZE45-1", "A0A3S5ZPN3-1", "P62207-1" ], "evidence": [ { "id": "R-GGA-9970190", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9970190" } ] }, { "id": "R-GGA-9970191", "name": "RBBP6 activates CPSF complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1NCB0-1", "E1BSC0-1", "A0A8V0YVP3-1", "Q5ZJL4-1", "A0A8V0ZWA8-1", "A0A8V0YUZ1-1", "F1NHI3-1", "A0A8V0Z2C0-1", "A0A8V0ZE45-1", "A0A3S5ZPN3-1", "P62207-1" ], "evidence": [ { "id": "R-GGA-9970191", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9970191" } ] } ], "reaction_participants": [ { "participant_id": "R-GGA-3900041", "participant_name": "DDX5 [nucleoplasm]", "crossref": [ { "id": "ENSGALG00010029634", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALT00010071653", "database": "ENSEMBL", "url": "" }, { "id": "XP_015135357.1", "database": "RefSeq", "url": "" }, { "id": "ENSGALP00010044343", "database": "ENSEMBL", "url": "" }, { "id": "A0A3S5ZPN3", "database": "UniProt", "url": "" }, { "id": "XP_046785210.1", "database": "RefSeq", "url": "" } ] }, { "participant_id": "R-GGA-3900136", "participant_name": "DDX5 [nucleoplasm]", "crossref": [ { "id": "A0A3S5ZPN3", "database": "UniProt", "url": "" }, { "id": "ENSGALG00010029634", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALP00010044343", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALT00010071653", "database": "ENSEMBL", "url": "" }, { "id": "XP_046785210.1", "database": "RefSeq", "url": "" }, { "id": "XP_015135357.1", "database": "RefSeq", "url": "" } ] }, { "participant_id": "R-GGA-3900186", "participant_name": "DDX5 [nucleoplasm]", "crossref": [ { "id": "ENSGALP00010044343", "database": "ENSEMBL", "url": "" }, { "id": "XP_046785210.1", "database": "RefSeq", "url": "" }, { "id": "A0A3S5ZPN3", "database": "UniProt", "url": "" }, { "id": "XP_015135357.1", "database": "RefSeq", "url": "" }, { "id": "ENSGALT00010071653", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALG00010029634", "database": "ENSEMBL", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5NTY5", "gene_name": "LOC430766", "activity": [ { "ec_number": "3.6.4.6", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5NTY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NTY5" } ] }, { "ec_number": "3.6.4.6", "activity": "", "evidence": [ { "id": "A0A1D5NTY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NTY5" } ] } ] }, { "uniprot_ac": "A0A1D5P5I0", "gene_name": "IFIH1", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5P5I0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P5I0" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A1D5P5I0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P5I0" } ] } ] }, { "uniprot_ac": "A0A1D5PD32", "gene_name": "DDX17", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5PD32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PD32" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A1D5PD32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PD32" } ] } ] }, { "uniprot_ac": "A0A1D5PHB6", "gene_name": "DHX36", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5PHB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PHB6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A1D5PHB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PHB6" } ] } ] }, { "uniprot_ac": "A0A1D5PIN7", "gene_name": "DHX30", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5PIN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PIN7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A1D5PIN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PIN7" } ] } ] }, { "uniprot_ac": "A0A1D5PRR9", "gene_name": "FANCM", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5PRR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRR9" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A1D5PRR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRR9" } ] } ] }, { "uniprot_ac": "A0A1D5PS27", "gene_name": "ENTPD2", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "A0A1D5PS27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PS27" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "A0A1D5PS27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PS27" } ] } ] }, { "uniprot_ac": "A0A1D5PVS9", "gene_name": "ENTPD3", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "A0A1D5PVS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PVS9" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "A0A1D5PVS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PVS9" } ] } ] }, { "uniprot_ac": "A0A1D5PW44", "gene_name": "PPIL1", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "A0A1D5PW44", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PW44" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "A0A1D5PW44", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PW44" } ] } ] }, { "uniprot_ac": "A0A1D5PZS0", "gene_name": "PRPF19", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A1D5PZS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZS0" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A1D5PZS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZS0" } ] } ] }, { "uniprot_ac": "A0A3S5ZPN3", "gene_name": "DDX5", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3S5ZPN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPN3" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A3S5ZPN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPN3" } ] } ] }, { "uniprot_ac": "A0A8V0X4Y2", "gene_name": "", "activity": [ { "ec_number": "2.3.1.48", "activity": "L-lysyl-[histone] + acetyl-CoA = N(6)-acetyl-L-lysyl-[histone] + CoA + H(+).", "evidence": [ { "id": "A0A8V0X4Y2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X4Y2" } ] }, { "ec_number": "2.3.1.48", "activity": "", "evidence": [ { "id": "A0A8V0X4Y2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X4Y2" } ] } ] }, { "uniprot_ac": "A0A8V0X600", "gene_name": "DDX43", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0X600", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X600" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0X600", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X600" } ] } ] }, { "uniprot_ac": "A0A8V0X655", "gene_name": "DHX32", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0X655", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X655" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0X655", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X655" } ] } ] }, { "uniprot_ac": "A0A8V0X6X9", "gene_name": "KAT2B", "activity": [ { "ec_number": "2.3.1.48", "activity": "L-lysyl-[histone] + acetyl-CoA = N(6)-acetyl-L-lysyl-[histone] + CoA + H(+).", "evidence": [ { "id": "A0A8V0X6X9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X6X9" } ] }, { "ec_number": "2.3.1.48", "activity": "", "evidence": [ { "id": "A0A8V0X6X9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X6X9" } ] } ] }, { "uniprot_ac": "A0A8V0X9Y7", "gene_name": "CFTR", "activity": [ { "ec_number": "5.6.1.6", "activity": "ATP + H2O + closed Cl(-) channel = ADP + phosphate + open Cl(-) channel.", "evidence": [ { "id": "A0A8V0X9Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X9Y7" } ] }, { "ec_number": "5.6.1.6", "activity": "", "evidence": [ { "id": "A0A8V0X9Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X9Y7" } ] } ] }, { "uniprot_ac": "A0A8V0X9Z6", "gene_name": "MOV10L1", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0X9Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X9Z6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0X9Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X9Z6" } ] } ] }, { "uniprot_ac": "A0A8V0XEC4", "gene_name": "DDX10", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XEC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEC4" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0XEC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEC4" } ] } ] }, { "uniprot_ac": "A0A8V0XG98", "gene_name": "HELQ", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XG98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XG98" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A8V0XG98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XG98" } ] } ] }, { "uniprot_ac": "A0A8V0XGV3", "gene_name": "DDX3X", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XGV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XGV3" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0XGV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XGV3" } ] } ] }, { "uniprot_ac": "A0A8V0XHD1", "gene_name": "AQR", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XHD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XHD1" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0XHD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XHD1" } ] } ] }, { "uniprot_ac": "A0A8V0XI26", "gene_name": "DDX1", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XI26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XI26" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0XI26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XI26" } ] } ] }, { "uniprot_ac": "A0A8V0XJV9", "gene_name": "SPATA5", "activity": [ { "ec_number": "3.6.4.6", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XJV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJV9" } ] }, { "ec_number": "3.6.4.6", "activity": "", "evidence": [ { "id": "A0A8V0XJV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJV9" } ] }, { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XJV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJV9" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "A0A8V0XJV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJV9" } ] } ] }, { "uniprot_ac": "A0A8V0XLC7", "gene_name": "MCM4", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XLC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLC7" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0A8V0XLC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLC7" } ] } ] }, { "uniprot_ac": "A0A8V0XMP8", "gene_name": "ZGRF1", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "A0A8V0XMP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMP8" } ] }, { "ec_number": "5.6.2.3", "activity": "", "evidence": [ { "id": "A0A8V0XMP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMP8" } ] } ] }, { "uniprot_ac": "A0A8V0XT73", "gene_name": "FBXO18", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XT73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XT73" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A8V0XT73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XT73" } ] } ] }, { "uniprot_ac": "A0A8V0XUB5", "gene_name": "PPIL4", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "A0A8V0XUB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XUB5" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "A0A8V0XUB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XUB5" } ] } ] }, { "uniprot_ac": "A0A8V0XX13", "gene_name": "LOC101748706", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XX13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XX13" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A8V0XX13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XX13" } ] } ] }, { "uniprot_ac": "A0A8V0XZB8", "gene_name": "DHX34", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XZB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XZB8" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0XZB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XZB8" } ] } ] }, { "uniprot_ac": "A0A8V0Y005", "gene_name": "HSPA9", "activity": [ { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0Y005", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y005" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "A0A8V0Y005", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y005" } ] } ] }, { "uniprot_ac": "A0A8V0Y0A4", "gene_name": "AK6", "activity": [ { "ec_number": "2.7.4.3", "activity": "AMP + ATP = 2 ADP.", "evidence": [ { "id": "A0A8V0Y0A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y0A4" } ] }, { "ec_number": "2.7.4.3", "activity": "", "evidence": [ { "id": "A0A8V0Y0A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y0A4" } ] } ] }, { "uniprot_ac": "A0A8V0Y1J8", "gene_name": "YTHDC2", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0Y1J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y1J8" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0Y1J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y1J8" } ] } ] }, { "uniprot_ac": "A0A8V0Y242", "gene_name": "DDX41", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0Y242", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y242" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0Y242", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y242" } ] } ] }, { "uniprot_ac": "A0A8V0YAA4", "gene_name": "XRCC6", "activity": [ { "ec_number": "4.2.99.18", "activity": "2'-deoxyribonucleotide-(2'-deoxyribose 5'-phosphate)-2'-deoxyribonucleotide-DNA = a 3'-end 2'-deoxyribonucleotide-(2,3-dehydro-2,3-deoxyribose 5'-phosphate)-DNA + a 5'-end 5'-phospho-2'-deoxyribonucleoside-DNA + H(+).", "evidence": [ { "id": "A0A8V0YAA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAA4" } ] }, { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YAA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAA4" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A8V0YAA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAA4" } ] }, { "ec_number": "4.2.99.18", "activity": "", "evidence": [ { "id": "A0A8V0YAA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAA4" } ] } ] }, { "uniprot_ac": "A0A8V0YCY8", "gene_name": "RIOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YCY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YCY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY8" } ] } ] }, { "uniprot_ac": "A0A8V0YFB8", "gene_name": "ATP13A4", "activity": [ { "ec_number": "7.2.2.-", "activity": "", "evidence": [ { "id": "A0A8V0YFB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFB8" } ] } ] }, { "uniprot_ac": "A0A8V0YFG2", "gene_name": "ATP13A5", "activity": [ { "ec_number": "7.2.2.-", "activity": "", "evidence": [ { "id": "A0A8V0YFG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFG2" } ] } ] }, { "uniprot_ac": "A0A8V0YGQ1", "gene_name": "DDX59", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YGQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGQ1" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0YGQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGQ1" } ] } ] }, { "uniprot_ac": "A0A8V0YHC8", "gene_name": "VCP", "activity": [ { "ec_number": "3.6.4.6", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YHC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHC8" } ] }, { "ec_number": "3.6.4.6", "activity": "", "evidence": [ { "id": "A0A8V0YHC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHC8" } ] } ] }, { "uniprot_ac": "A0A8V0YJ98", "gene_name": "EP300", "activity": [ { "ec_number": "2.3.1.48", "activity": "L-lysyl-[histone] + acetyl-CoA = N(6)-acetyl-L-lysyl-[histone] + CoA + H(+).", "evidence": [ { "id": "A0A8V0YJ98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ98" } ] }, { "ec_number": "2.3.1.48", "activity": "", "evidence": [ { "id": "A0A8V0YJ98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ98" } ] } ] }, { "uniprot_ac": "A0A8V0YLC1", "gene_name": "DDX11", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "A0A8V0YLC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLC1" } ] }, { "ec_number": "5.6.2.3", "activity": "", "evidence": [ { "id": "A0A8V0YLC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLC1" } ] } ] }, { "uniprot_ac": "A0A8V0YLM0", "gene_name": "RECQL", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YLM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLM0" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A8V0YLM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLM0" } ] } ] }, { "uniprot_ac": "A0A8V0YNF9", "gene_name": "DDX27", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YNF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNF9" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0YNF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNF9" } ] } ] }, { "uniprot_ac": "A0A8V0YQS3", "gene_name": "MCM9", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YQS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQS3" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A8V0YQS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQS3" } ] } ] }, { "uniprot_ac": "A0A8V0YRH6", "gene_name": "ERCC6L", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YRH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRH6" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0A8V0YRH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRH6" } ] } ] }, { "uniprot_ac": "A0A8V0YT68", "gene_name": "ATRX", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YT68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YT68" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0A8V0YT68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YT68" } ] } ] }, { "uniprot_ac": "A0A8V0YU49", "gene_name": "DHX29", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YU49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YU49" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0YU49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YU49" } ] } ] }, { "uniprot_ac": "A0A8V0YUC5", "gene_name": "SKIV2L2", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YUC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUC5" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0YUC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUC5" } ] } ] }, { "uniprot_ac": "A0A8V0YUG9", "gene_name": "TDRD9", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YUG9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUG9" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0YUG9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUG9" } ] } ] }, { "uniprot_ac": "A0A8V0YUW3", "gene_name": "EIF4A2", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YUW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUW3" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0YUW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUW3" } ] } ] }, { "uniprot_ac": "A0A8V0YUZ1", "gene_name": "PAPOLB", "activity": [ { "ec_number": "2.7.7.19", "activity": "RNA(n) + ATP = RNA(n)-3'-adenine ribonucleotide + diphosphate.", "evidence": [ { "id": "A0A8V0YUZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUZ1" } ] }, { "ec_number": "2.7.7.19", "activity": "", "evidence": [ { "id": "A0A8V0YUZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUZ1" } ] } ] }, { "uniprot_ac": "A0A8V0YVP3", "gene_name": "RBBP6", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YVP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVP3" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YVP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVP3" } ] } ] }, { "uniprot_ac": "A0A8V0Z1F9", "gene_name": "DHX57", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0Z1F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1F9" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0Z1F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1F9" } ] } ] }, { "uniprot_ac": "A0A8V0Z289", "gene_name": "DDX24", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0Z289", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z289" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0Z289", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z289" } ] } ] }, { "uniprot_ac": "A0A8V0Z2C0", "gene_name": "PAPOLG", "activity": [ { "ec_number": "2.7.7.19", "activity": "RNA(n) + ATP = RNA(n)-3'-adenine ribonucleotide + diphosphate.", "evidence": [ { "id": "A0A8V0Z2C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2C0" } ] }, { "ec_number": "2.7.7.19", "activity": "", "evidence": [ { "id": "A0A8V0Z2C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2C0" } ] } ] }, { "uniprot_ac": "A0A8V0Z2M8", "gene_name": "MCM8", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0Z2M8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2M8" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A8V0Z2M8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2M8" } ] } ] }, { "uniprot_ac": "A0A8V0Z3A2", "gene_name": "PPIE", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "A0A8V0Z3A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3A2" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "A0A8V0Z3A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3A2" } ] } ] }, { "uniprot_ac": "A0A8V0Z5P2", "gene_name": "RHOT2", "activity": [ { "ec_number": "3.6.5.-", "activity": "", "evidence": [ { "id": "A0A8V0Z5P2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5P2" } ] } ] }, { "uniprot_ac": "A0A8V0Z655", "gene_name": "SNRNP200", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0Z655", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z655" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0Z655", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z655" } ] } ] }, { "uniprot_ac": "A0A8V0Z659", "gene_name": "TWNK", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "A0A8V0Z659", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z659" } ] }, { "ec_number": "5.6.2.3", "activity": "", "evidence": [ { "id": "A0A8V0Z659", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z659" } ] } ] }, { "uniprot_ac": "A0A8V0ZC95", "gene_name": "MCM6", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZC95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC95" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0A8V0ZC95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC95" } ] } ] }, { "uniprot_ac": "A0A8V0ZE45", "gene_name": "DDX42", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZE45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE45" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0ZE45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE45" } ] } ] }, { "uniprot_ac": "A0A8V0ZEN5", "gene_name": "DDX19", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZEN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEN5" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0ZEN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEN5" } ] } ] }, { "uniprot_ac": "A0A8V0ZFN9", "gene_name": "DDX54", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZFN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFN9" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0ZFN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFN9" } ] } ] }, { "uniprot_ac": "A0A8V0ZIP8", "gene_name": "XRCC5", "activity": [ { "ec_number": "4.2.99.18", "activity": "2'-deoxyribonucleotide-(2'-deoxyribose 5'-phosphate)-2'-deoxyribonucleotide-DNA = a 3'-end 2'-deoxyribonucleotide-(2,3-dehydro-2,3-deoxyribose 5'-phosphate)-DNA + a 5'-end 5'-phospho-2'-deoxyribonucleoside-DNA + H(+).", "evidence": [ { "id": "A0A8V0ZIP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIP8" } ] }, { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZIP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIP8" } ] }, { "ec_number": "4.2.99.18", "activity": 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ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZS62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS62" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZS62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS62" } ] } ] }, { "uniprot_ac": "A0A8V0ZTR5", "gene_name": "LOC423693", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZTR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTR5" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0ZTR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTR5" } ] } ] }, { "uniprot_ac": "A0A8V0ZU13", "gene_name": "PPIG", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "A0A8V0ZU13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU13" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "A0A8V0ZU13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU13" } ] } ] }, { "uniprot_ac": "A0A8V0ZU49", "gene_name": "DNA2", "activity": [ { "ec_number": "3.1.-.-", "activity": "", "evidence": [ { "id": "A0A8V0ZU49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU49" } ] }, { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZU49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU49" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0A8V0ZU49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU49" } ] } ] }, { "uniprot_ac": "A0A8V0ZUQ0", "gene_name": "DDX21", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZUQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUQ0" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0ZUQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUQ0" } ] } ] }, { "uniprot_ac": "A0A8V0ZUR5", "gene_name": "DDX6", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZUR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUR5" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0ZUR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUR5" } ] } ] }, { "uniprot_ac": "A0A8V0ZUT3", "gene_name": "DHX58", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZUT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUT3" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0ZUT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUT3" } ] } ] }, { "uniprot_ac": "A0A8V0ZVY2", "gene_name": "RTEL1", "activity": [ { "ec_number": "5.6.2.-", "activity": "", "evidence": [ { "id": "A0A8V0ZVY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVY2" } ] } ] }, { "uniprot_ac": "A0A8V0ZWA8", "gene_name": "PPP1CA", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZWA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWA8" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZWA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWA8" } ] } ] }, { "uniprot_ac": "A0A8V0ZWH7", "gene_name": "DHX35", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZWH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWH7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0ZWH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWH7" } ] } ] }, { "uniprot_ac": "A0A8V0ZZF5", "gene_name": "DHX8", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZZF5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZF5" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0ZZF5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZF5" } ] } ] }, { "uniprot_ac": "A0A8V0ZZK3", "gene_name": "SUPV3L1", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZZK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZK3" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0ZZK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZK3" } ] } ] }, { "uniprot_ac": "A0A8V1A3M1", "gene_name": "DDX55", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1A3M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3M1" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V1A3M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3M1" } ] } ] }, { "uniprot_ac": "A0A8V1A4V3", "gene_name": "POLQ", "activity": [ { "ec_number": "2.7.7.7", "activity": "DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate.", "evidence": [ { "id": "A0A8V1A4V3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V3" } ] }, { "ec_number": "2.7.7.49", "activity": "DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate.", "evidence": [ { "id": "A0A8V1A4V3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V3" } ] }, { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1A4V3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V3" } ] }, { "ec_number": "2.7.7.7", "activity": "", "evidence": [ { "id": "A0A8V1A4V3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V3" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0A8V1A4V3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V3" } ] }, { "ec_number": "2.7.7.49", "activity": "", "evidence": [ { "id": "A0A8V1A4V3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V3" } ] } ] }, { "uniprot_ac": "A0A8V1A5D6", "gene_name": "DDX51", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1A5D6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5D6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V1A5D6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5D6" } ] } ] }, { "uniprot_ac": "A0A8V1A712", "gene_name": "", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1A712", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A712" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V1A712", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A712" } ] } ] }, { "uniprot_ac": "A0A8V1A7M6", "gene_name": "", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1A7M6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V1A7M6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M6" } ] } ] }, { "uniprot_ac": "A0A8V1A7P4", "gene_name": "DDX49", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1A7P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P4" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V1A7P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P4" } ] } ] }, { "uniprot_ac": "A0A8V1A8Y2", "gene_name": "ENTPD8", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "A0A8V1A8Y2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8Y2" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "A0A8V1A8Y2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8Y2" } ] } ] }, { "uniprot_ac": "A0A8V1ACD8", "gene_name": "NSF", "activity": [ { "ec_number": "3.6.4.6", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1ACD8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACD8" } ] }, { "ec_number": "3.6.4.6", "activity": "", "evidence": [ { "id": "A0A8V1ACD8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACD8" } ] } ] }, { "uniprot_ac": "A0A8V1ADZ7", "gene_name": "RHOT1", "activity": [ { "ec_number": "3.6.5.-", "activity": "", "evidence": [ { "id": "A0A8V1ADZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADZ7" } ] } ] }, { "uniprot_ac": "A0A8V1AE46", "gene_name": "ENTPD8L1", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "A0A8V1AE46", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE46" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "A0A8V1AE46", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE46" } ] } ] }, { "uniprot_ac": "A0A8V1AER6", "gene_name": "MOV10", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1AER6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AER6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V1AER6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AER6" } ] } ] }, { "uniprot_ac": "A0A8V1AFG8", "gene_name": "RECQL5", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1AFG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFG8" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A8V1AFG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFG8" } ] } ] }, { "uniprot_ac": "A0A8V1AFJ9", "gene_name": "MCM2", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1AFJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFJ9" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0A8V1AFJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFJ9" } ] } ] }, { "uniprot_ac": "A0A8V1AIK2", "gene_name": "DDX25", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1AIK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIK2" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V1AIK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIK2" } ] } ] }, { "uniprot_ac": "A0A8V1AJ43", "gene_name": "DHX40", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1AJ43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ43" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V1AJ43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ43" } ] } ] }, { "uniprot_ac": "A0A8V1AJY9", "gene_name": "DDX31", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1AJY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJY9" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V1AJY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJY9" } ] } ] }, { "uniprot_ac": "A0A8V1AKU6", "gene_name": "HELZ", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1AKU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKU6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V1AKU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKU6" } ] } ] }, { "uniprot_ac": "A0A8V1AL41", "gene_name": "DHX33", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1AL41", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL41" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V1AL41", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL41" } ] } ] }, { "uniprot_ac": "A0A8V1ALH0", "gene_name": "RNF213", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1ALH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALH0" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1ALH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALH0" } ] } ] }, { "uniprot_ac": "B6ZLK2", "gene_name": "CHD1", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "B6ZLK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B6ZLK2" } ] } ] }, { "uniprot_ac": "E1BSC0", "gene_name": "DDX46", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BSC0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BSC0" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1BSC0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BSC0" } ] } ] }, { "uniprot_ac": "E1BY42", "gene_name": "IGHMBP2", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BY42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY42" } ] }, { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BY42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY42" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1BY42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY42" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "E1BY42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY42" } ] } ] }, { "uniprot_ac": "F1N8Z4", "gene_name": "RUVBL1", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1N8Z4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N8Z4" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "F1N8Z4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N8Z4" } ] } ] }, { "uniprot_ac": "F1N991", "gene_name": "DDX4", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1N991", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N991" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1N991", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N991" } ] } ] }, { "uniprot_ac": "F1NA92", "gene_name": "CLPX", "activity": [ { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1NA92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NA92" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "F1NA92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NA92" } ] } ] }, { "uniprot_ac": "F1NAJ2", "gene_name": "PPWD1", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "F1NAJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NAJ2" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "F1NAJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NAJ2" } ] } ] }, { "uniprot_ac": "F1NCB0", "gene_name": "POLR2B", "activity": [ { "ec_number": "2.7.7.6", "activity": "RNA(n) + a ribonucleoside 5'-triphosphate = RNA(n+1) + diphosphate.", "evidence": [ { "id": "F1NCB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCB0" } ] }, { "ec_number": "2.7.7.6", "activity": "", "evidence": [ { "id": "F1NCB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCB0" } ] } ] }, { "uniprot_ac": "F1ND48", "gene_name": "FBH1", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1ND48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1ND48" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "F1ND48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1ND48" } ] } ] }, { "uniprot_ac": "F1NFJ0", "gene_name": "MCM3", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1NFJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NFJ0" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "F1NFJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NFJ0" } ] } ] }, { "uniprot_ac": "F1NHI3", "gene_name": "DHX15", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1NHI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NHI3" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1NHI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NHI3" } ] } ] }, { "uniprot_ac": "F1NN44", "gene_name": "ALPL", "activity": [ { "ec_number": "3.1.3.1", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "F1NN44", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NN44" } ] }, { "ec_number": "3.1.3.1", "activity": "", "evidence": [ { "id": "F1NN44", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NN44" } ] } ] }, { "uniprot_ac": "F1NQJ3", "gene_name": "PMS2", "activity": [ { "ec_number": "3.1.-.-", "activity": "", "evidence": [ { "id": "F1NQJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NQJ3" } ] } ] }, { "uniprot_ac": "F1NTD6", "gene_name": "ascc3", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1NTD6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NTD6" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "F1NTD6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NTD6" } ] } ] }, { "uniprot_ac": "F1NZ23", "gene_name": "ERCC3", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1NZ23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NZ23" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "F1NZ23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NZ23" } ] } ] }, { "uniprot_ac": "F1P5C0", "gene_name": "DDX20", "activity": [ { "ec_number": "3.6.1.15", "activity": "a ribonucleoside 5'-triphosphate + H2O = a ribonucleoside 5'-diphosphate + phosphate + H(+).", "evidence": [ { "id": "F1P5C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P5C0" } ] }, { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1P5C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P5C0" } ] }, { "ec_number": "3.6.1.15", "activity": "", "evidence": [ { "id": "F1P5C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P5C0" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1P5C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P5C0" } ] } ] }, { "uniprot_ac": "I0IUP3", "gene_name": "MCM8", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "I0IUP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/I0IUP3" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "I0IUP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/I0IUP3" } ] } ] }, { "uniprot_ac": "I0IUP4", "gene_name": "MCM9", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "I0IUP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/I0IUP4" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "I0IUP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/I0IUP4" } ] } ] }, { "uniprot_ac": "O12944", "gene_name": "RAD54L", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "O12944", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O12944" } ] } ] }, { "uniprot_ac": "O93257", "gene_name": "XRCC6", "activity": [ { "ec_number": "4.2.99.18", "activity": "2'-deoxyribonucleotide-(2'-deoxyribose 5'-phosphate)-2'-deoxyribonucleotide-DNA = a 3'-end 2'-deoxyribonucleotide-(2,3-dehydro-2,3-deoxyribose 5'-phosphate)-DNA + a 5'-end 5'-phospho-2'-deoxyribonucleoside-DNA + H(+).", "evidence": [ { "id": "O93257", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O93257" } ] }, { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "O93257", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O93257" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "O93257", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O93257" } ] }, { "ec_number": "4.2.99.18", "activity": "", "evidence": [ { "id": "O93257", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O93257" } ] } ] }, { "uniprot_ac": "O93295", "gene_name": "ENTPD8", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "O93295", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O93295" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "O93295", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O93295" } ] } ] }, { "uniprot_ac": "P08023", "gene_name": "ACTA2", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "P08023", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P08023" } ] } ] }, { "uniprot_ac": "P08110", "gene_name": "HSP90B1", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "P08110", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P08110" } ] } ] }, { "uniprot_ac": "P37383", "gene_name": "RAD51A", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "P37383", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P37383" } ] } ] }, { "uniprot_ac": "P53478", "gene_name": "", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "P53478", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P53478" } ] } ] }, { "uniprot_ac": "P60706", "gene_name": "ACTB", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "P60706", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P60706" } ] } ] }, { "uniprot_ac": "P62207", "gene_name": "PPP1CB", "activity": [ { "ec_number": "3.1.3.53", "activity": "O-phospho-L-threonyl-[myosin light chain] + H2O = L-threonyl-[myosin light chain] + phosphate.", "evidence": [ { "id": "P62207", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P62207" } ] }, { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P62207", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P62207" } ] }, { "ec_number": "3.1.3.53", "activity": "", "evidence": [ { "id": "P62207", "database": "UniProtKB", "url": 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"id": "P68139", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P68139" } ] } ] }, { "uniprot_ac": "P79784", "gene_name": "ENTPD2", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "P79784", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P79784" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "P79784", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P79784" } ] } ] }, { "uniprot_ac": "Q06A37", "gene_name": "CHD7", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "Q06A37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q06A37" } ] } ] }, { "uniprot_ac": "Q3YK19", "gene_name": "BRIP1", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "Q3YK19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3YK19" } ] }, { "ec_number": "5.6.2.3", "activity": "", "evidence": [ { "id": "Q3YK19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3YK19" } ] } ] }, { "uniprot_ac": "Q5F485", "gene_name": "DDX42", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q5F485", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F485" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "Q5F485", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F485" } ] } ] }, { "uniprot_ac": "Q5ZHZ0", "gene_name": "DDX39B", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q5ZHZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZHZ0" } ] }, { "ec_number": 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"url": "https://www.uniprot.org/uniprotkb/Q5ZIW1" } ] } ] }, { "uniprot_ac": "Q5ZJ54", "gene_name": "CCT6", "activity": [ { "ec_number": "3.6.1.-", "activity": "", "evidence": [ { "id": "Q5ZJ54", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJ54" } ] } ] }, { "uniprot_ac": "Q5ZJF6", "gene_name": "DDX10", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q5ZJF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJF6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "Q5ZJF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJF6" } ] } ] }, { "uniprot_ac": "Q5ZJK8", "gene_name": "CCT7", "activity": [ { "ec_number": "3.6.1.-", "activity": "", "evidence": [ { "id": "Q5ZJK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJK8" } ] } ] }, { "uniprot_ac": "Q5ZJL4", "gene_name": "CLP1", "activity": [ { "ec_number": 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"database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05625/entry#names_and_taxonomy" } ] }, { "name": "MIL proto-oncogene serine/threonine-protein kinase", "type": "synonym", "evidence": [ { "id": "NP_990638", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990638" }, { "id": "P05625", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05625/entry#names_and_taxonomy" } ] }, { "name": "RAF proto-oncogene serine/threonine-protein kinase", "type": "synonym", "evidence": [ { "id": "NP_990638", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990638" } ] }, { "name": "RAF-1", "type": "synonym", "evidence": [ { "id": "P05625", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05625/entry#names_and_taxonomy" } ] }, { "name": "c-mil protein", "type": "synonym", "evidence": [ { "id": "NP_990638", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990638" } ] }, { "name": "v-raf-1 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The reference sequence was derived from X07017.1.", "evidence": [ { "database": "RefSeq", "id": "NP_990638", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990638" } ] }, { "annotation": "A complete map of the c-mil/raf-1 gene and a revision of the exon numbers", "evidence": [ { "database": "RefSeq", "id": "NP_990638", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990638" }, { "database": "PubMed", "id": "14968114", "url": "https://glygen.org/publication/PubMed/14968114" } ] }, { "annotation": "Inducible gene deletion of the c-mil/raf-1 gene in chicken DT40 B cells revealed that, in addition to B-Raf, Raf-1 acts as an accessory ERK activator following engagement of the B cell antigen receptor.", "evidence": [ { "database": "RefSeq", "id": "NP_990638", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990638" }, { "database": "PubMed", "id": "12411479", "url": "https://glygen.org/publication/PubMed/12411479" } ] }, { "annotation": "RAF kinase activity is essential to establish the balance between cell proliferation and death in neuroepithelial otic precursors, and for otic neuron differentiation and axonal growth at the acoustic-vestibular ganglion Publication Status: Online-Only", "evidence": [ { "database": "RefSeq", "id": "NP_990638", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990638" }, { "database": "PubMed", "id": "21203386", "url": "https://glygen.org/publication/PubMed/21203386" } ] }, { "annotation": "Serine/threonine-protein kinase that acts as a regulatory link between the membrane-associated Ras GTPases and the MAPK/ERK cascade, and this critical regulatory link functions as a switch determining cell fate decisions. RAF1 activation initiates a mitogen-activated protein kinase (MAPK) cascade that comprises a sequential phosphorylation of the dual-specific MAPK kinases (MAP2K1/MEK1 and MAP2K2/MEK2) and the extracellular signal-regulated kinases (MAPK3/ERK1 and MAPK1/ERK2) (By similarity).", "evidence": [ { "database": "UniProtKB", "id": "P05625", "url": "https://www.uniprot.org/uniprotkb/P05625#function" }, { "database": "UniProtKB", "id": "P04049", "url": "https://www.uniprot.org/uniprotkb/P04049#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "P05625", "url": "https://www.uniprot.org/uniprotkb/P05625" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RAF1", "url": "https://www.uniprot.org/uniprotkb/P05625", "locus": { "chromosome": "12", "start_pos": 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"https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20870", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "396245", "url": "https://www.ncbi.nlm.nih.gov/gene/396245", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001245", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001245", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002219", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002219", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008271", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008271", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017441", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017441", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020454", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020454", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029071", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029071", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046349", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046349", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051681", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051681", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:396245", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:396245", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SAYKRHA", "url": "https://omabrowser.org/oma/group/SAYKRHA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A452J7W6", "url": "https://www.orthodb.org/?gene=A0A452J7W6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "P05625", "url": "https://www.orthodb.org/?gene=P05625", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR44329", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44329", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR44329:SF22", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44329:SF22", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00130", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00130", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02196", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02196", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07714", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07714", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:P05625", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:P05625", "database": "PRO", "categories": [ "Protein" ] }, { "id": "R-GGA-2672351", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2672351", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-392517", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-392517", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-430116", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-430116", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5621575", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5621575", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5673000", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5673000", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5674135", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5674135", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5674499", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5674499", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5675221", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5675221", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9732724", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9732724", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_990638", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990638", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "17989", "url": "https://www.rhea-db.org/rhea/17989", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "46608", "url": "https://www.rhea-db.org/rhea/46608", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A452J7W6", "url": "https://www.uniprot.org/uniprotkb/A0A452J7W6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A452J7W6-1", "url": "https://www.uniprot.org/uniprotkb/A0A452J7W6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P05625", "url": "https://www.uniprot.org/uniprotkb/P05625", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P05625-1", "url": "https://www.uniprot.org/uniprotkb/P05625-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P05625-2", "url": "https://www.uniprot.org/uniprotkb/P05625-2", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEHIQGAWKTISNGFGLKDSVFDGPNCISPTIVQQFGYQRRASDDGKISDTSKTSNTIRVFLPNKQRTVVNVRNGMTLHDCLMKALKVRGLQPECCAVFRLVTEPKGKKVRLDWNTDAASLIGEELQVDFLDHVPLTTHNFARKTFLKLAFCDICQKFLLNGFRCQTCGYKFHEHCSTKVPTMCVDWSNIRQLLLFPNSNISDSGVPALPPLTMRRMRESVSRIPVSSQHRYSTPHVFTFNTSNPSSEGTLSQRQRSTSTPNVHMVSTTMPVDSRIIEDAIRNHSESASPSALSGSPNNMSPTGWSQPKTPVPAQRERAPGTNTQEKNKIRPRGQRDSSYYWEIEASEVMLSTRIGSGSFGTVYKGKWHGDVAVKILKVVDPTPEQFQAFRNEVAVLRKTRHVNILLFMGYMTKDNLAIVTQWCEGSSLYKHLHVQETKFQMFQLIDIARQTAQGMDYLHAKNIIHRDMKSNNIFLHEGLTVKIGDFGLATVKSRWSGSQQVEQPTGSILWMAPEVIRMQDSNPFSFQSDVYSYGIVLYELMTGELPYSHINNRDQIIFMVGRGYASPDLSKLYKNCPKAMKRLVADCLKKVREERPLFPQILSSIELLQHSLPKINRSASEPSLHRASHTEDINSCTLTSTRLPVF", "length": 647, "header": "sp|P05625-1|RAF1_CHICK Isoform 1 of RAF proto-oncogene serine/threonine-protein kinase OS=Gallus gallus OX=9031 GN=RAF1 PE=2 SV=1 CANONICAL=P05625-1" }, "isoforms": [ { "isoform_ac": "A0A452J7W6-1", "url": "https://www.uniprot.org/uniprotkb/P05625/entry#A0A452J7W6-1", "sequence": { "sequence": "MEHIQGAWKTISNGFGLKDSVFDGPNCISPTIVQQFGYQRRASDDGKISDTSKTSNTIRVFLPNKQRTVVNVRNGMTLHDCLMKALKVRGLQPECCAVFRLVTEPKGKKVRLDWNTDAASLIGEELQVDFLDHVPLTTHNFARKTFLKLAFCDICQKFLLNGFRCQTCGYKFHEHCSTKVPTMCVDWSNIRQLFSQHRYSTPHVFTFNTSNPSSEGTLSQRQRSTSTPNVHMVSTTMPVDSRIIENNSLNASPSSWCRRFCLRGRDAIRNHSESASPSALSGSPNNMSPTGWSQPKTPVPAQRERAPGTNTQEKNKIRPRGQRDSSYYWEIEASEVMLSTRIGSGSFGTVYKGKWHGDVAVKILKVVDPTPEQFQAFRNEVAVLRKTRHVNILLFMGYMTKDNLAIVTQWCEGSSLYKHLHVQETKFQMFQLIDIARQTAQGMDYLHAKNIIHRDMKSNNIFLHEGLTVKIGDFGLATVKSRWSGSQQVEQPTGSILWMAPEVIRMQDSNPFSFQSDVYSYGIVLYELMTGELPYSHINNRDQIIFMVGRGYASPDLSKLYKNCPKAMKRLVADCLKKVREERPLFPQILSSIELLQHSLPKINRSASEPSLHRASHTEDINSCTLTSTRLPVF", "length": 634, "header": "tr|A0A452J7W6-1|RAF1_CHICK Computationally mapped isoform of RAF proto-oncogene serine/threonine-protein kinase OS=Gallus gallus OX=9031 GN=RAF1 PE=2 SV=1 CANONICAL=P05625-1" }, "locus": { "chromosome": "12", "start_pos": 5157269, "end_pos": 5136902, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067701.1", "url": "https://www.ensembl.org/id/ENSGALT00010067701.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041444.1", "url": "https://www.ensembl.org/id/ENSGALP00010041444.1" } ] } }, { "isoform_ac": "P05625-1", "url": "https://www.uniprot.org/uniprotkb/P05625/entry#P05625-1", "sequence": { "sequence": "MEHIQGAWKTISNGFGLKDSVFDGPNCISPTIVQQFGYQRRASDDGKISDTSKTSNTIRVFLPNKQRTVVNVRNGMTLHDCLMKALKVRGLQPECCAVFRLVTEPKGKKVRLDWNTDAASLIGEELQVDFLDHVPLTTHNFARKTFLKLAFCDICQKFLLNGFRCQTCGYKFHEHCSTKVPTMCVDWSNIRQLLLFPNSNISDSGVPALPPLTMRRMRESVSRIPVSSQHRYSTPHVFTFNTSNPSSEGTLSQRQRSTSTPNVHMVSTTMPVDSRIIEDAIRNHSESASPSALSGSPNNMSPTGWSQPKTPVPAQRERAPGTNTQEKNKIRPRGQRDSSYYWEIEASEVMLSTRIGSGSFGTVYKGKWHGDVAVKILKVVDPTPEQFQAFRNEVAVLRKTRHVNILLFMGYMTKDNLAIVTQWCEGSSLYKHLHVQETKFQMFQLIDIARQTAQGMDYLHAKNIIHRDMKSNNIFLHEGLTVKIGDFGLATVKSRWSGSQQVEQPTGSILWMAPEVIRMQDSNPFSFQSDVYSYGIVLYELMTGELPYSHINNRDQIIFMVGRGYASPDLSKLYKNCPKAMKRLVADCLKKVREERPLFPQILSSIELLQHSLPKINRSASEPSLHRASHTEDINSCTLTSTRLPVF", "length": 647, "header": "sp|P05625-1|RAF1_CHICK Isoform 1 of RAF proto-oncogene serine/threonine-protein kinase OS=Gallus gallus OX=9031 GN=RAF1 PE=2 SV=1 CANONICAL=P05625-1" }, "locus": { "chromosome": "12", "start_pos": 5157269, "end_pos": 5136902, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067703.1", "url": "https://www.ensembl.org/id/ENSGALT00010067703.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041446.1", "url": "https://www.ensembl.org/id/ENSGALP00010041446.1" } ] } }, { "isoform_ac": "P05625-2", "url": "https://www.uniprot.org/uniprotkb/P05625/entry#P05625-2", "sequence": { "sequence": "MEHIQGAWKTISNGFGLKDSVFDGPNCISPTIVQQFGYQRRASDDGKISDTSKTSNTIRVFLPNKQRTVVNVRNGMTLHDCLMKALKVRGLQPECCAVFRLVTEPKGKKVRLDWNTDAASLIGEELQVDFLDHVPLTTHNFARKTFLKLAFCDICQKFLLNGFRCQTCGYKFHEHCSTKVPTMCVDWSNIRQLLLFPNSNISDSGVPALPPLTMRRMRESVSRIPVSSQHRYSTPHVFTFNTSNPSSEGTLSQRQRSTSTPNVHMVSTTMPVDSRIIENNSLNASPSSWCRRFCLRGRDAIRNHSESASPSALSGSPNNMSPTGWSQPKTPVPAQRERAPGTNTQEKNKIRPRGQRDSSYYWEIEASEVMLSTRIGSGSFGTVYKGKWHGDVAVKILKVVDPTPEQFQAFRNEVAVLRKTRHVNILLFMGYMTKDNLAIVTQWCEGSSLYKHLHVQETKFQMFQLIDIARQTAQGMDYLHAKNIIHRDMKSNNIFLHEGLTVKIGDFGLATVKSRWSGSQQVEQPTGSILWMAPEVIRMQDSNPFSFQSDVYSYGIVLYELMTGELPYSHINNRDQIIFMVGRGYASPDLSKLYKNCPKAMKRLVADCLKKVREERPLFPQILSSIELLQHSLPKINRSASEPSLHRASHTEDINSCTLTSTRLPVF", "length": 667, "header": "sp|P05625-2|RAF1_CHICK Isoform 2 of RAF proto-oncogene serine/threonine-protein kinase OS=Gallus gallus OX=9031 GN=RAF1 PE=2 SV=1 CANONICAL=P05625-1" }, "locus": { "chromosome": "12", "start_pos": 5157269, "end_pos": 5136902, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067700.1", "url": "https://www.ensembl.org/id/ENSGALT00010067700.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041443.1", "url": "https://www.ensembl.org/id/ENSGALP00010041443.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 383, "start_aa": "Thr", "end_pos": 383, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr383", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [ { "start_pos": 259, "end_pos": 259, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P05625", "url": "https://www.uniprot.org/uniprotkb/P05625" } ], "site_lbl": "Ser259" }, { "start_pos": 268, "end_pos": 268, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine; by autocatalysis", "evidence": [ { "database": "UniProtKB", "id": "P05625", "url": "https://www.uniprot.org/uniprotkb/P05625" } ], "site_lbl": "Thr268" }, { "start_pos": 338, "end_pos": 338, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P05625", "url": "https://www.uniprot.org/uniprotkb/P05625" }, { "database": "iPTMnet", "id": "P05625", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P05625" }, { "database": "PubMed", "id": "12843393", "url": "https://glygen.org/publication/PubMed/12843393" }, { "database": "PubMed", "id": "12952943", "url": "https://glygen.org/publication/PubMed/12952943" } ], "site_lbl": "Ser338" }, { "start_pos": 339, "end_pos": 339, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P05625", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P05625" }, { "database": "PubMed", "id": "12843393", "url": "https://glygen.org/publication/PubMed/12843393" } ], "site_lbl": "Ser339" }, { "start_pos": 340, "end_pos": 340, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P05625", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P05625" }, { "database": "PubMed", "id": "12952943", "url": "https://glygen.org/publication/PubMed/12952943" } ], "site_lbl": "Tyr340" }, { "start_pos": 341, "end_pos": 341, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P05625", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P05625" }, { "database": "PubMed", "id": "12952943", "url": "https://glygen.org/publication/PubMed/12952943" } ], "site_lbl": "Tyr341" }, { "start_pos": 43, "end_pos": 43, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P05625", "url": "https://www.uniprot.org/uniprotkb/P05625" } ], "site_lbl": "Ser43" }, { "start_pos": 499, "end_pos": 499, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P05625", "url": "https://www.uniprot.org/uniprotkb/P05625" } ], "site_lbl": "Ser499" }, { "start_pos": 621, "end_pos": 621, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P05625", "url": "https://www.uniprot.org/uniprotkb/P05625" } ], "site_lbl": "Ser621" } ], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "Inducible gene deletion reveals different roles for B-Raf and Raf-1 in B-cell antigen receptor signalling.", "journal": "The EMBO journal", "date": "2002-11-01", "authors": "Brummer Tilman, Shaw Peter E, Reth Michael, Misawa Yukiko", "evidence": [ { "database": "RefSeq", "id": "NP_990638", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990638" } ], "reference": [ { "type": "PubMed", "id": "12411479", "url": "https://glygen.org/publication/PubMed/12411479" } ] }, { "title": "Role of Raf in vascular protection from distinct apoptotic stimuli.", "journal": "Science (New York, N.Y.)", "date": "2003", "authors": "Alavi A, Hood JD, Frausto R, Stupack DG, Cheresh DA", "evidence": [ { "database": "iPTMnet", "id": "P05625", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P05625" } ], "reference": [ { "type": "PubMed", "id": "12843393", "url": "https://glygen.org/publication/PubMed/12843393" } ] }, { "title": "Differential alphav integrin-mediated Ras-ERK signaling during two pathways of angiogenesis.", "journal": "The Journal of cell biology", "date": "2003-09-01", "authors": "Hood John D, Frausto Ricardo, Kiosses William B, Schwartz Martin A, Cheresh David A", "evidence": [ { "database": "iPTMnet", "id": "P05625", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P05625" } ], "reference": [ { "type": "PubMed", "id": "12952943", "url": "https://glygen.org/publication/PubMed/12952943" } ] }, { "title": "A revised and complete map of the chicken c-mil/raf-1 locus.", "journal": "Oncogene", "date": "2004-04-15", "authors": "Brummer Tilman, St\u00e9helin Dominique, Misawa Yukiko, Reth Michael", "evidence": [ { "database": "RefSeq", "id": "NP_990638", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990638" } ], "reference": [ { "type": "PubMed", "id": "14968114", "url": "https://glygen.org/publication/PubMed/14968114" } ] }, { "title": "An alternatively spliced c-mil/raf mRNA is predominantly expressed in chicken muscular tissues and conserved among vertebrate species.", "journal": "Oncogene", "date": "1991", "authors": "Dozier C, Ansieau S, Ferreira E, Coll J, Stehelin D", "evidence": [ { "database": "UniProtKB", "id": "P05625", "url": "https://www.uniprot.org/uniprotkb/P05625" } ], "reference": [ { "type": "PubMed", "id": "1886707", "url": "https://glygen.org/publication/PubMed/1886707" } ] }, { "title": "RAF kinase activity regulates neuroepithelial cell proliferation and neuronal progenitor cell differentiation during early inner ear development.", "journal": "PloS one", "date": "2010-12-28", "authors": "Magari\u00f1os Marta, Aburto Mar\u00eda R, S\u00e1nchez-Calder\u00f3n Hortensia, Mu\u00f1oz-Agudo Carmen, Rapp Ulf R, Varela-Nieto Isabel", "evidence": [ { "database": "RefSeq", "id": "NP_990638", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990638" } ], "reference": [ { "type": "PubMed", "id": "21203386", "url": "https://glygen.org/publication/PubMed/21203386" } ] }, { "title": "Alternative splicing of RNAs transcribed from the chicken c-mil gene.", "journal": "Mol. Cell. Biol.", "date": "1988", "authors": "Dozier C, Denhez F, Henry C, Coll J, Begue A, Quatannens B, Saule S, Stehelin D", "evidence": [ { "database": "UniProtKB", "id": "P05625", "url": "https://www.uniprot.org/uniprotkb/P05625" } ], "reference": [ { "type": "PubMed", "id": "2837658", "url": "https://glygen.org/publication/PubMed/2837658" } ] }, { "title": "Nucleotide sequence analysis of the chicken gene c-mil, the progenitor of the retroviral oncogene v-mil.", "journal": "Virology", "date": "1985", "authors": "Jansen H W, Bister K", "evidence": [ { "database": "UniProtKB", "id": "P05625", "url": "https://www.uniprot.org/uniprotkb/P05625" } ], "reference": [ { "type": "PubMed", "id": "2998016", "url": "https://glygen.org/publication/PubMed/2998016" } ] }, { "title": "Analysis of the cellular proto-oncogene mht/raf: relationship to the 5' sequences of v-mht in avian carcinoma virus MH2 and v-raf in murine sarcoma virus 3611.", "journal": "Virology", "date": "1985", "authors": "Flordellis C S, Kan N C, Lautenberger J A, Samuel K P, Garon C F, Papas T S", "evidence": [ { "database": "UniProtKB", "id": "P05625", "url": "https://www.uniprot.org/uniprotkb/P05625" } ], "reference": [ { "type": "PubMed", "id": "3002017", "url": "https://glygen.org/publication/PubMed/3002017" } ] }, { "title": "Primary structure of the chicken c-mil protein: identification of domains shared with or absent from the retroviral v-mil protein.", "journal": "Oncogene", "date": "1988", "authors": "Koenen M, Sippel A E, Trachmann C, Bister K", "evidence": [ { "database": "UniProtKB", "id": "P05625", "url": "https://www.uniprot.org/uniprotkb/P05625" } ], "reference": [ { "type": "PubMed", "id": "3285296", "url": "https://glygen.org/publication/PubMed/3285296" } ] } ], "pathway": [ { "id": "gga:396245", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:396245", "resource": "KEGG Pathway" }, { "id": "R-GGA-2672351", "name": "", "url": 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"common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 8, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "P05625", "url": "https://www.uniprot.org/uniprotkb/P05625" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "P05625", "url": "https://www.uniprot.org/uniprotkb/P05625" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "P05625", "url": "https://www.uniprot.org/uniprotkb/P05625" } ], "pmid": "" }, { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "P05625", "url": "https://www.uniprot.org/uniprotkb/P05625" } ], "pmid": "" }, { "name": "MAP kinase kinase kinase activity", "id": "GO:0004709", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004709", "evidence": [ { "database": "UniProtKB", "id": "P05625", "url": "https://www.uniprot.org/uniprotkb/P05625" } ], "pmid": "" }, { "name": "adenylate cyclase activator activity", "id": "GO:0010856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010856", "evidence": [ { "database": "UniProtKB", "id": "P05625", "url": "https://www.uniprot.org/uniprotkb/P05625" } ], "pmid": "" }, { "name": "protein serine kinase activity", "id": "GO:0106310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106310", "evidence": [ { "database": "UniProtKB", "id": "P05625", "url": "https://www.uniprot.org/uniprotkb/P05625" } ], "pmid": "" }, { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "P05625", "url": "https://www.uniprot.org/uniprotkb/P05625" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P05625", "url": "https://www.uniprot.org/uniprotkb/P05625" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P05625", "url": "https://www.uniprot.org/uniprotkb/P05625" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "P05625", "url": "https://www.uniprot.org/uniprotkb/P05625" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P05625", "url": "https://www.uniprot.org/uniprotkb/P05625" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "P05625", "url": "https://www.uniprot.org/uniprotkb/P05625" } ], "pmid": "" }, { "name": "pseudopodium", "id": "GO:0031143", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031143", "evidence": [ { "database": "UniProtKB", "id": "P05625", "url": "https://www.uniprot.org/uniprotkb/P05625" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 12, "go_terms": [ { "name": "neuromuscular junction development", "id": "GO:0007528", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007528", "evidence": [ { "database": "UniProtKB", "id": "P05625", "url": "https://www.uniprot.org/uniprotkb/P05625" } ], "pmid": "" }, { "name": "negative regulation of cell population proliferation", "id": "GO:0008285", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008285", "evidence": [ { "database": "UniProtKB", "id": "P05625", "url": "https://www.uniprot.org/uniprotkb/P05625" } ], "pmid": "" }, { "name": "negative regulation of apoptotic process", "id": "GO:0043066", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043066", "evidence": [ { "database": "UniProtKB", "id": "P05625", "url": "https://www.uniprot.org/uniprotkb/P05625" } ], "pmid": "" }, { "name": "positive regulation of MAPK cascade", "id": "GO:0043410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043410", "evidence": [ { "database": "UniProtKB", "id": "P05625", "url": "https://www.uniprot.org/uniprotkb/P05625" } ], "pmid": "" }, { "name": "MAPK cascade", "id": "GO:0000165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000165", "evidence": [ { "database": "UniProtKB", "id": "P05625", "url": "https://www.uniprot.org/uniprotkb/P05625" } ], "pmid": "" }, { "name": "myelination", "id": "GO:0042552", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042552", "evidence": [ { "database": "UniProtKB", "id": "P05625", "url": "https://www.uniprot.org/uniprotkb/P05625" } ], "pmid": "" }, { "name": "insulin receptor signaling pathway", "id": "GO:0008286", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008286", "evidence": [ { "database": "UniProtKB", "id": "P05625", "url": "https://www.uniprot.org/uniprotkb/P05625" } ], "pmid": "" }, { "name": "negative regulation of protein-containing complex assembly", "id": "GO:0031333", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031333", "evidence": [ { "database": "UniProtKB", "id": "P05625", "url": "https://www.uniprot.org/uniprotkb/P05625" } ], "pmid": "" }, { "name": "insulin-like growth factor receptor signaling pathway", "id": "GO:0048009", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048009", "evidence": [ { "database": "UniProtKB", "id": "P05625", "url": "https://www.uniprot.org/uniprotkb/P05625" } ], "pmid": "" }, { "name": "Schwann cell development", "id": "GO:0014044", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014044", "evidence": [ { "database": "UniProtKB", "id": "P05625", "url": "https://www.uniprot.org/uniprotkb/P05625" } ], "pmid": "" }, { "name": "ERBB2-ERBB3 signaling pathway", "id": "GO:0038133", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038133", "evidence": [ { "database": "UniProtKB", "id": "P05625", "url": "https://www.uniprot.org/uniprotkb/P05625" } ], "pmid": "" }, { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "P05625", "url": "https://www.uniprot.org/uniprotkb/P05625" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 200, "end_pos": 202, "annotation": "n_glycosylation_sequon" }, { "start_pos": 241, "end_pos": 243, "annotation": "n_glycosylation_sequon" }, { "start_pos": 283, "end_pos": 285, "annotation": "n_glycosylation_sequon" }, { "start_pos": 299, "end_pos": 301, "annotation": "n_glycosylation_sequon" }, { "start_pos": 617, "end_pos": 619, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "17989", "name": "", "equation": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q6U1I9-1", "A0A8V0XNJ2-1", "A0A8V0ZUL0-1", "A0A8V0ZT63-1", "A0A8V1ACW2-1", "A0A8V0Z1X0-1", "A0A8V0YHN2-1", "A0A8V0YMN5-1", "A0A8V0Z807-1", "A0A8V0Z930-1", "A0A8V0YFR6-1", "A0A1D5P0M9-1", "A0A8V0ZBN6-1", "A0A3Q2U9U9-1", "A0A8V0YXZ5-1", "A0A8V0ZSP4-1", "A0A8V0ZXQ9-1", "A0A8V0ZZV3-1", "A0A8V1ADF0-1", "A0A8V0ZFT3-1", "A0A8V0ZA45-1", "A0A8V0ZB33-1", "A0A8V0ZD70-1", "A0A8V0Z8T4-1", "R4GIN8-1", "A0A8V0ZK64-1", "A0A8V0ZC16-1", "A0A8V0ZWW1-1", "E1BY69-1", "A0A8V0ZDW9-1", "A0A8V0ZKA2-1", "A0A3Q3B2F1-1", "F1P356-1", "A0A8V1AHA8-1", "Q8QFP8-1", "F1P011-1", "A0A8V0YKK3-1", "A0A1D5NWT4-1", "A0A1D5PMQ7-1", "E1BWA3-1", "F1NVF2-1", "A0A1D5PXN4-1", "A0A3Q2TY19-1", 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"E1BQN6-1", "A0A8V0XU71-1", "Q5ZJH6-1", "A0A8V0Y3D1-1", "A0A8V0Y7C3-1", "A0A8V0YCY4-1", "A0A8V0YIV6-1", "A0A8V0YK18-1", "A0A8V0YM22-1", "A0A8V0YTN5-1", "A0A8V0YTP2-1", "Q5F3L1-1", "A0A8V0XU96-1", "E1C6T4-1", "A0A8V0Y3L2-1", "A0A8V0YCY8-1", "A0A8V0Y9Q1-1", "A0A8V0ZD48-1", "A0A8V0ZD60-1", "A0A8V0ZBZ2-1", "A0A8V0Z9J0-1", "A0A8V1ABF3-1", "Q8AYC9-1", "A0A8V0Z927-1", "A0A8V1A2T9-1", "Q5ZKI0-1", "Q7T0B1-1", "P10741-1", "A0A8V1AMK5-1", "P67962-1", "A0A8V0YFH4-1", "E1C848-1", "A0A8V0X8M1-1", "E1BW33-1", "A0A8V0Z283-1", "A0A8V0Z157-1", "A0A3Q2U4X3-1", "A0A8V0XW11-1", "E1BUG0-1", "A0A8V1ABP4-1", "A0A8V1AJA4-1", "A0A8V1AEH4-1", "F1NJH1-1", "A0A3Q2TRY2-1", "A0A8V0X3D6-1", "A0A1D5PD64-1", "A0A8V0XQ97-1", "R4GJB8-1", "A0A8V0X5Z8-1", "A0A8V0XG21-1", "A0A8V0XB58-1", "A0A8V0XMX8-1", "A0A8V0XQS0-1", "A0A8V0XW29-1", "A0A8V0Y074-1", "A0A8V0XXB8-1", "A0A8V0XQ14-1", "A0A8V0XI18-1", "A0A8V0XMT1-1", "A0A8V0Y457-1", "A0A8V0Y823-1", "A0A8V0Y4L8-1", "A0A8V0XND6-1", "A0A8V0Y8X9-1", "A0A8V0YZ74-1", "A0A8V0YTI1-1", "A0A8V0YLV1-1", "A0A8V0Z2E3-1", "A0A8V0YCV9-1", "A0A8V0YSH3-1", "A0A8V0YYX2-1", "A0A8V0YZY4-1", "Q5ZIU3-1", "A0A8V0YZK0-1", "A0A8V0ZKM9-1", "A0A8V0ZWC7-1", "A0A8V1A1Y7-1", "A0A8V1A069-1", "A0A8V0ZI32-1", "A0A8V0ZH91-1", "E1BQV7-1", "A0A8V0ZRX1-1", "A0A8V0ZUU9-1", "A0A8V1A0Y8-1", "A0A8V1A7E9-1", "A0A8V1A7E0-1", "A0A8V1A3T8-1", "A0A8V1A9S5-1", "A0A8V1A7M0-1", "A0A8V1A675-1", "A0A8V1A1P3-1", "A0A8V1ADT4-1", "E1BWT0-1", "A0A8V1ACF6-1", "A0A8V1ADN9-1", "A0A8V1AM12-1", "A0A8V1A4Q4-1", "Q90891-1", "F1NUX4-1", "A0A8V0ZZE4-1", "P05625-1", "P13863-1", "Q04982-2", "Q0GGW5-1", "Q6XUX0-1", "Q8QGX4-1", "Q9I9E0-1", "Q9IA88-1", "Q5ZJK4-1", "A0A1D5PTJ8-1", "E1C2I2-1", "F1NCX7-1", "F1NKW3-1", "A0A8V1A0W4-1", "A0A8V1A4J8-1", "A0A8V1ACK0-1", "F1NCY7-1", "A0A8V0X6T4-1", "A0A8V0XUM6-1", "A0A8V0XEA3-1", "A0A8V0YHH2-1", "A0A3Q2UI52-1", "A0A8V0ZZK5-1", "A0A8V0ZPX2-1", "A0A8V1ACB5-1", "A0A8V0YDH4-1", "A0A8V1AFS4-1", "A0A8V1AH12-1", "A0A8V0ZQT5-1", "A0A8V0ZFP1-1", "E1C764-1", "F1P4G3-1", "A0A8V0Y2I5-1", "A0A8V0ZLU3-1", "A0A8V0ZNP7-1", "A0A8V0Z2Z3-1", "A0A8V0YNI5-1", "Q90771-1", "A0A8V0X4P0-1", "A0A8V0X7R2-1", "A0A3Q3A664-1", "A0A8V0YGW2-1", "E1C581-1", "A0A8V1AC40-1", "A0A3Q2TUS7-1", "A0A1D5PA08-1", "A0A8V0XFW1-1", "A0A8V0XAH9-1", "A0A8V0ZFM2-1", "A0A8V1A4A1-1", "A0A8V0ZD40-1", "A0A8V0Z6T1-1", "A0A8V1A4V7-1", "A0A8V0YZF2-1", "E1BX69-1", "A0A8V0Y955-1", "A0A1D5PB73-1", "A0A1D5PV76-1", "A0A1D5PX90-1", "A0A1L1RWI9-1", "A0A3Q2TV19-1", "A0A3Q2UF44-1", "A0A8V0X4Q3-1", "A0A8V0Z124-1", "A0A8V0Z6K4-1", "A0A8V1AIY7-1", "A0A8V1AE45-1", "A0A8V0YZV9-1", "A0A8V0YYZ3-1", "A0A8V0ZUC6-1", "A0A8V0ZUU8-1", "A0A8V1AG70-1", "F1NA68-1", "F1NLR7-1", "A0A8V0Y6K1-1", "A0A8V0XS42-1", "A0A8V0YRN4-1", "A0A8V0YFP8-1", "A0A8V1A7P9-1", "A0A1D5PRN8-1", "A0A3Q3AAD7-1", "A0A3Q2TWZ8-1", "A0A8V0XBZ0-1", "A0A8V0XFX2-1", "A0A8V0YFL1-1", "A0A8V0YTL9-1", "A0A8V0YMB3-1", "A0A8V0X2Y2-1", "A0A8V0XCY6-1", "A0A3Q2UI62-1", "A0A8V0Y241-1", "A0A8V0Z8G2-1", "A0A8V1ABR8-1", "A0A8V1AP60-1", "A0A8V0YZM1-1", "A0A8V0ZB38-1", "A0A8V0Z466-1", "A0A8V0ZA06-1", "A0A8V1AMQ2-1", "A0A8V0ZGY3-1", "A0A8V0ZQJ2-1", "A0A8V0ZYU6-1", "A0A8V1A513-1", "A0A8V0XE48-1", "A0A8V0XKG0-1" ], "evidence": [ { "id": "46608", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/46608" } ] }, { "id": "R-GGA-2682349", "name": "RAF1:SGK:TSC22D3:WPP ubiquitinates SCNN channels", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [ "R-ALL-947590" ], "enzyme_list": [ "A0A8V0XFW1-1", "A0A8V1AHA8-1", "Q6U1I9-1", "A0A3Q2UC96-1", "A0A8V0ZFT3-1", "P05625-1", "A0A8V0YDQ1-1" ], "evidence": [ { "id": "R-GGA-2682349", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2682349" } ] }, { "id": "R-GGA-392835", "name": "Rap1 sequesters Raf1 to inhibit ERK cascade", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q5ZHX1-1", "F1NSA8-1", "P05625-1" ], "evidence": [ { "id": "R-GGA-392835", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-392835" } ] }, { "id": "R-GGA-443439", "name": "c-Src binds Raf1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZDU6-1", "P05625-1" ], "evidence": [ { "id": "R-GGA-443439", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-443439" } ] }, { "id": "R-GGA-443831", "name": "14-3-3-zeta binds Raf1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P05625-1" ], "evidence": [ { "id": "R-GGA-443831", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-443831" } ] }, { "id": "R-GGA-5624486", "name": "SFKs phosphorylates RAF1 on Y340,Y341", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XHW1-1", "Q5F352-1", "A0A3Q2U639-1", "P05625-1", "P08642-1" ], "evidence": [ { "id": "R-GGA-5624486", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5624486" } ] }, { "id": "R-GGA-5624492", "name": "PAK phosphorylates p21 RAF1 on S338", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BS97-1", "E1C3P6-1", "Q5F352-1", "A0A8V0YYX2-1", "P05625-1", "P08642-1" ], "evidence": [ { "id": "R-GGA-5624492", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5624492" } ] }, { "id": "R-GGA-5624494", "name": "RAF1 binds p21 RAS:GTP", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q5F352-1", "P05625-1", "P08642-1" ], "evidence": [ { "id": "R-GGA-5624494", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5624494" } ] }, { "id": "R-GGA-5672950", "name": "Activator\" RAF:YWHAB dimer binds RAS:GTP\"", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q5F352-1", "A0A8V1AP60-1", "P05625-1", "P08642-1", "A0A8V0YMN5-1" ], "evidence": [ { "id": "R-GGA-5672950", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5672950" } ] }, { "id": "R-GGA-5672951", "name": "Inactive RAFs bind YWHAB", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P05625-1", "A0A8V0YMN5-1" ], "evidence": [ { "id": "R-GGA-5672951", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5672951" } ] }, { "id": "R-GGA-5672960", "name": "YWHAB dimer dissociates from dephosphorylated RAF", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P05625-1", "A0A8V0YMN5-1" ], "evidence": [ { "id": "R-GGA-5672960", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5672960" } ] }, { "id": "R-GGA-5672966", "name": "RAS:GTP:'activator' RAF homo/heterodimerizes with other RAF monomers", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q5F352-1", "A0A8V1AP60-1", "A0A8V0ZZ54-1", "P05625-1", "P08642-1", "A0A8V0YLV1-1", "A0A8V0YMN5-1" ], "evidence": [ { "id": "R-GGA-5672966", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5672966" } ] }, { "id": "R-GGA-5672969", "name": "Phosphorylation of RAF", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q5F352-1", "A0A8V1AP60-1", "A0A8V0YNY4-1", "A0A8V0ZDU6-1", "P05625-1", "P08642-1", "A0A8V0YLV1-1", "A0A8V0YMN5-1" ], "evidence": [ { "id": "R-GGA-5672969", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5672969" } ] }, { "id": "R-GGA-5672973", "name": "MAP2Ks phosphorylate MAPKs", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P53478-1", "Q5F352-1", "A0A1D5PX90-1", "Q5ZHX1-1", "A0A8V1AP60-1", "A0A8V0ZND5-1", "F1NSA8-1", "A0A8V1A4Q4-1", "A0A8V0ZDU6-1", "P05625-1", "P08642-1", "Q5ZMQ2-1", "A0A8V0YLV1-1", "A0A8V0YMN5-1" ], "evidence": [ { "id": "R-GGA-5672973", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5672973" } ] }, { "id": "R-GGA-5672978", "name": "RAF phosphorylates MAP2K dimer", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P53478-1", "Q5F352-1", "A0A1D5PX90-1", "Q5ZHX1-1", "A0A8V1AP60-1", "A0A8V0ZND5-1", "F1NSA8-1", "A0A8V1A4Q4-1", "A0A8V0ZDU6-1", "P05625-1", "P08642-1", "Q5ZMQ2-1", "A0A8V0YLV1-1", "A0A8V0YMN5-1" ], "evidence": [ { "id": "R-GGA-5672978", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5672978" } ] }, { "id": "R-GGA-5674140", "name": "PAQR3 binds inactive RAFs", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "Golgi membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P05625-1", "A0A8V0YMN5-1" ], "evidence": [ { "id": "R-GGA-5674140", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5674140" } ] }, { "id": "R-GGA-5675194", "name": "Activated MAPK phosphorylates RAF1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [ "R-GGA-5672665" ], "output_participant_list": [ "R-GGA-5675193" ], "enzyme_list": [ "A0A8V1A4Q4-1", "P05625-1" ], "evidence": [ { "id": "R-GGA-5675194", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5675194" } ] }, { "id": "R-GGA-5675417", "name": "PEBP1 binds activated RAF1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q5F352-1", "A0A8V1AP60-1", "P05625-1", "P08642-1", "A0A8V0YMN5-1" ], "evidence": [ { "id": "R-GGA-5675417", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5675417" } ] }, { "id": "R-GGA-9653108", "name": "Raf dimer inhibitors bind RAF heterodimers", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q5F352-1", "A0A8V1AP60-1", "P05625-1", "P08642-1", "A0A8V0YLV1-1", "A0A8V0YMN5-1" ], "evidence": [ { "id": "R-GGA-9653108", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9653108" } ] }, { "id": "R-GGA-9657599", "name": "Dual mechanism MAP2K inhibitors bind MAP2Ks", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P53478-1", "Q5F352-1", "A0A1D5PX90-1", "Q5ZHX1-1", "A0A8V1AP60-1", "A0A8V0ZND5-1", "F1NSA8-1", "A0A8V1A4Q4-1", "A0A8V0ZDU6-1", "P05625-1", "P08642-1", "Q5ZMQ2-1", "A0A8V0YLV1-1", "A0A8V0YMN5-1" ], "evidence": [ { "id": "R-GGA-9657599", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9657599" } ] }, { "id": "R-GGA-9657603", "name": "Dual mechanism MAPK inhibitors bind MAPKs", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P53478-1", "Q5F352-1", "A0A1D5PX90-1", "Q5ZHX1-1", "A0A8V1AP60-1", "A0A8V0ZND5-1", "F1NSA8-1", "A0A8V1A4Q4-1", "A0A8V0ZDU6-1", "P05625-1", "P08642-1", "Q5ZMQ2-1", "A0A8V0YLV1-1", "A0A8V0YMN5-1" ], "evidence": [ { "id": "R-GGA-9657603", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9657603" } ] }, { "id": "R-GGA-9657606", "name": "Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P53478-1", "Q5F352-1", "A0A1D5PX90-1", "Q5ZHX1-1", "A0A8V1AP60-1", "A0A8V0ZND5-1", "F1NSA8-1", "A0A8V1A4Q4-1", "A0A8V0ZDU6-1", "P05625-1", "P08642-1", "Q5ZMQ2-1", "A0A8V0YLV1-1", "A0A8V0YMN5-1" ], "evidence": [ { "id": "R-GGA-9657606", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9657606" } ] }, { "id": "R-GGA-9657608", "name": "Single mechanism MAPK inhibitors bind phosphorylated MAPK", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P53478-1", "Q5F352-1", "A0A1D5PX90-1", "Q5ZHX1-1", "A0A8V1AP60-1", "A0A8V0ZND5-1", "F1NSA8-1", "A0A8V1A4Q4-1", "A0A8V0ZDU6-1", "P05625-1", "P08642-1", "Q5ZMQ2-1", "A0A8V0YLV1-1", "A0A8V0YMN5-1" ], "evidence": [ { "id": "R-GGA-9657608", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9657608" } ] }, { "id": "R-GGA-9658445", "name": "MRAS:SHOC2:PPP1CC dephosphorylates inactive RAFs", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZYK3-1", "P05625-1", "P62207-1", "A0A8V0YMN5-1" ], "evidence": [ { "id": "R-GGA-9658445", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9658445" } ] }, { "id": "R-GGA-9732729", "name": "Activated JAK1 binds RAF1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZSN8-1", "A0A8V0YNY4-1", "P05625-1" ], "evidence": [ { "id": "R-GGA-9732729", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9732729" } ] }, { "id": "R-GGA-9732738", "name": "JAK1-mediated phosphorylation of RAF1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZSN8-1", "A0A8V0YNY4-1", "P05625-1" ], "evidence": [ { "id": "R-GGA-9732738", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9732738" } ] }, { "id": "R-GGA-9732753", "name": "JAK1-activated RAF1 phosphorylates MAPKs", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZSN8-1", "A0A8V1A4Q4-1", "A0A8V0YNY4-1", "P05625-1" ], "evidence": [ { "id": "R-GGA-9732753", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9732753" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-947590", "participant_name": "Pi [plasma membrane]", "crossref": [ { "id": "43474", "database": "ChEBI", "url": "" }, { "id": "C00009", "database": "COMPOUND", "url": "" } ] }, { "participant_id": "R-GGA-5672665", "participant_name": "phospho-p-S338,Y341,T491,S494,S621 RAF1 [plasma membrane]", "crossref": [ { "id": "P05625", "database": "UniProt", "url": "" }, { "id": "P05625", "database": "PRO", "url": "" }, { "id": "ENSGALT00010067700", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALT00010067703", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALP00010041446", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALP00010041443", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALG00010027930", "database": "ENSEMBL", "url": "" } ] }, { "participant_id": "R-GGA-5675193", "participant_name": "phospho-hyperphosphorylated RAF1 [plasma membrane]", "crossref": [ { "id": "ENSGALT00010067703", "database": "ENSEMBL", "url": "" }, { "id": "P05625", "database": "PRO", "url": "" }, { "id": "ENSGALP00010041443", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALG00010027930", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALT00010067700", "database": "ENSEMBL", "url": "" }, { "id": "P05625", "database": "UniProt", "url": "" }, { "id": "ENSGALP00010041446", "database": "ENSEMBL", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5NWT4", "gene_name": "RPS6KA3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5NWT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NWT4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5NWT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NWT4" } ] } ] }, { "uniprot_ac": "A0A1D5P0M9", "gene_name": "MAP3K13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5P0M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P0M9" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A1D5P0M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P0M9" } ] } ] }, { "uniprot_ac": "A0A1D5P517", "gene_name": "PLK3", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5P517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P517" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A1D5P517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P517" } ] } ] }, { "uniprot_ac": "A0A1D5P8A9", "gene_name": "SNRK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5P8A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P8A9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5P8A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P8A9" } ] } ] }, { "uniprot_ac": "A0A1D5PA08", "gene_name": "STK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PA08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PA08" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5PA08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PA08" } ] } ] }, { "uniprot_ac": "A0A1D5PB73", "gene_name": "CASK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PB73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PB73" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5PB73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PB73" } ] } ] }, { "uniprot_ac": "A0A1D5PD64", "gene_name": "MAP2K3", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PD64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PD64" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A1D5PD64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PD64" } ] } ] }, { "uniprot_ac": "A0A1D5PMG2", "gene_name": "DCLK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PMG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMG2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5PMG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMG2" } ] } ] }, { "uniprot_ac": "A0A1D5PMQ7", "gene_name": "STK40", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PMQ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMQ7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5PMQ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMQ7" } ] } ] }, { "uniprot_ac": "A0A1D5PRN8", "gene_name": "DAPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PRN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRN8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5PRN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRN8" } ] } ] }, { "uniprot_ac": "A0A1D5PTJ8", "gene_name": "MAP3K5", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PTJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PTJ8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A1D5PTJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PTJ8" } ] } ] }, { "uniprot_ac": "A0A1D5PUY5", "gene_name": "PRKCB", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PUY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUY5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A1D5PUY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUY5" } ] } ] }, { "uniprot_ac": "A0A1D5PV76", "gene_name": "STK17A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PV76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PV76" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5PV76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PV76" } ] } ] }, { "uniprot_ac": "A0A1D5PX90", "gene_name": "KSR2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PX90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PX90" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5PX90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PX90" } ] } ] }, { "uniprot_ac": "A0A1D5PXN4", "gene_name": "PRKCD", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PXN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PXN4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A1D5PXN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PXN4" } ] } ] }, { "uniprot_ac": "A0A1L1RWI9", "gene_name": "CAMK4", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1L1RWI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RWI9" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A1L1RWI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RWI9" } ] } ] }, { "uniprot_ac": "A0A3Q2TRY2", "gene_name": "TAOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2TRY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TRY2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q2TRY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TRY2" } ] } ] }, { "uniprot_ac": "A0A3Q2TUS7", "gene_name": "TLK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2TUS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TUS7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q2TUS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TUS7" } ] } ] }, { "uniprot_ac": "A0A3Q2TV19", "gene_name": "UHMK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2TV19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TV19" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q2TV19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TV19" } ] } ] }, { "uniprot_ac": "A0A3Q2TWZ8", "gene_name": "MAP3K20", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2TWZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TWZ8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A3Q2TWZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TWZ8" } ] } ] }, { "uniprot_ac": "A0A3Q2TY19", "gene_name": "MAPK8", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2TY19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TY19" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A3Q2TY19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TY19" } ] } ] }, { "uniprot_ac": "A0A3Q2U4X3", "gene_name": "AKT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2U4X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U4X3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q2U4X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U4X3" } ] } ] }, { "uniprot_ac": "A0A3Q2U592", "gene_name": "DCLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2U592", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U592" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q2U592", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U592" } ] } ] }, { "uniprot_ac": "A0A3Q2U639", "gene_name": "FYN", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2U639", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U639" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A3Q2U639", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U639" } ] } ] }, { "uniprot_ac": "A0A3Q2U9U9", "gene_name": "OXSR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2U9U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U9U9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q2U9U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U9U9" } ] } ] }, { "uniprot_ac": "A0A3Q2UC96", "gene_name": "NEDD4L", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A3Q2UC96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UC96" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A3Q2UC96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UC96" } ] } ] }, { "uniprot_ac": "A0A3Q2UF44", "gene_name": "NEK8", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2UF44", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UF44" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q2UF44", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UF44" } ] } ] }, { "uniprot_ac": "A0A3Q2UI52", "gene_name": "LATS2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2UI52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UI52" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q2UI52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UI52" } ] } ] }, { "uniprot_ac": "A0A3Q2UI62", "gene_name": "CDK10", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2UI62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UI62" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A3Q2UI62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UI62" } ] } ] }, { "uniprot_ac": "A0A3Q3A664", "gene_name": "CDK17", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q3A664", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3A664" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A3Q3A664", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3A664" } ] } ] }, { "uniprot_ac": "A0A3Q3AAD7", "gene_name": "STK35", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q3AAD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3AAD7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q3AAD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3AAD7" } ] } ] }, { "uniprot_ac": "A0A3Q3B2F1", "gene_name": "PKN3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q3B2F1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3B2F1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A3Q3B2F1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3B2F1" } ] } ] }, { "uniprot_ac": "A0A8V0X1Q7", "gene_name": "MELK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X1Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X1Q7" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X1Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X1Q7" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0X1Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X1Q7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0X1Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X1Q7" } ] } ] }, { "uniprot_ac": "A0A8V0X2Y2", "gene_name": "MAPK12", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X2Y2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X2Y2" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0X2Y2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X2Y2" } ] } ] }, { "uniprot_ac": "A0A8V0X3D6", "gene_name": "LOC100858386", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X3D6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X3D6" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0X3D6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X3D6" } ] } ] }, { "uniprot_ac": "A0A8V0X4P0", "gene_name": "CDKL5", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X4P0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X4P0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0X4P0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X4P0" } ] } ] }, { "uniprot_ac": "A0A8V0X4Q3", "gene_name": "ICK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X4Q3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X4Q3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0X4Q3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X4Q3" } ] } ] }, { "uniprot_ac": "A0A8V0X5Z8", "gene_name": "NEK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X5Z8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X5Z8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0X5Z8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X5Z8" } ] } ] }, { "uniprot_ac": "A0A8V0X6T4", "gene_name": "LOC107050692", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X6T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X6T4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0X6T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X6T4" } ] } ] }, { "uniprot_ac": "A0A8V0X7R2", "gene_name": "SBK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X7R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X7R2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0X7R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X7R2" } ] } ] }, { "uniprot_ac": "A0A8V0X8M1", "gene_name": "TRIO", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X8M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X8M1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0X8M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X8M1" } ] } ] }, { "uniprot_ac": "A0A8V0XAH9", "gene_name": "NEK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XAH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XAH9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XAH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XAH9" } ] } ] }, { "uniprot_ac": "A0A8V0XB58", "gene_name": "CAMK2D", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XB58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XB58" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V0XB58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XB58" } ] } ] }, { "uniprot_ac": "A0A8V0XBZ0", "gene_name": "STK32C", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XBZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XBZ0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XBZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XBZ0" } ] } ] }, { "uniprot_ac": "A0A8V0XCS0", "gene_name": "PRKG2", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XCS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCS0" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0A8V0XCS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCS0" } ] } ] }, { "uniprot_ac": "A0A8V0XCV5", "gene_name": "MAP3K7", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XCV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCV5" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0XCV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCV5" } ] } ] }, { "uniprot_ac": "A0A8V0XCY6", "gene_name": "TTK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XCY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCY6" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V0XCY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCY6" } ] } ] }, { "uniprot_ac": "A0A8V0XDR5", "gene_name": "IRAK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XDR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XDR5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XDR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XDR5" } ] } ] }, { "uniprot_ac": "A0A8V0XE48", "gene_name": "ROCK2", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XE48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XE48" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "A0A8V0XE48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XE48" } ] } ] }, { "uniprot_ac": "A0A8V0XEA3", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XEA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEA3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XEA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEA3" } ] } ] }, { "uniprot_ac": "A0A8V0XFW1", "gene_name": "SGK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XFW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFW1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XFW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFW1" } ] } ] }, { "uniprot_ac": "A0A8V0XFX2", "gene_name": "NEK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XFX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFX2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XFX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFX2" } ] } ] }, { "uniprot_ac": "A0A8V0XG21", "gene_name": "LOC107050335", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XG21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XG21" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XG21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XG21" } ] } ] }, { "uniprot_ac": "A0A8V0XHW1", "gene_name": "LYN", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XHW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XHW1" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0XHW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XHW1" } ] } ] }, { "uniprot_ac": "A0A8V0XI18", "gene_name": "ATM", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XI18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XI18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XI18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XI18" } ] } ] }, { "uniprot_ac": "A0A8V0XKG0", "gene_name": "NEK9", "activity": [ { "ec_number": "2.7.11.38", "activity": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XKG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XKG0" } ] }, { "ec_number": "2.7.11.38", "activity": "", "evidence": [ { "id": "A0A8V0XKG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XKG0" } ] } ] }, { "uniprot_ac": "A0A8V0XLV6", "gene_name": "MAPK10", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XLV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLV6" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0XLV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLV6" } ] } ] }, { "uniprot_ac": "A0A8V0XMT1", "gene_name": "MOS", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XMT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMT1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XMT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMT1" } ] } ] }, { "uniprot_ac": "A0A8V0XMX8", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMX8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMX8" } ] } ] }, { "uniprot_ac": "A0A8V0XND6", "gene_name": "RIOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XND6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XND6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XND6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XND6" } ] } ] }, { "uniprot_ac": "A0A8V0XNJ2", "gene_name": "CDK8", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] } ] }, { "uniprot_ac": "A0A8V0XNK8", "gene_name": "PRKCQ", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XNK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNK8" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0XNK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNK8" } ] } ] }, { "uniprot_ac": "A0A8V0XQ14", "gene_name": "PLK4", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQ14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ14" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A8V0XQ14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ14" } ] } ] }, { "uniprot_ac": "A0A8V0XQ97", "gene_name": "CDK14", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQ97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ97" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0XQ97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ97" } ] } ] }, { "uniprot_ac": "A0A8V0XQQ4", "gene_name": "NME7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQQ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQQ4" } ] } ] }, { "uniprot_ac": "A0A8V0XQS0", "gene_name": "STK24", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQS0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XQS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQS0" } ] } ] }, { "uniprot_ac": "A0A8V0XS42", "gene_name": "MAP3K4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XS42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XS42" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0XS42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XS42" } ] } ] }, { "uniprot_ac": "A0A8V0XU71", "gene_name": "MYO3A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XU71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU71" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XU71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU71" } ] } ] }, { "uniprot_ac": "A0A8V0XU96", "gene_name": "PRKD1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XU96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU96" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0XU96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU96" } ] } ] }, { "uniprot_ac": "A0A8V0XUM6", "gene_name": "LATS1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XUM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XUM6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XUM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XUM6" } ] } ] }, { "uniprot_ac": "A0A8V0XW11", "gene_name": "RPS6KA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XW11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW11" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XW11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW11" } ] } ] }, { "uniprot_ac": "A0A8V0XW29", "gene_name": "CDKL2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XW29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW29" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0XW29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW29" } ] } ] }, { "uniprot_ac": "A0A8V0XXB8", "gene_name": "MAPK15", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XXB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXB8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0XXB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXB8" } ] } ] }, { "uniprot_ac": "A0A8V0Y074", "gene_name": "NEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y074", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y074" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y074", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y074" } ] } ] }, { "uniprot_ac": "A0A8V0Y241", "gene_name": "LOC426385", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y241", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y241" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y241", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y241" } ] } ] }, { "uniprot_ac": "A0A8V0Y2I5", "gene_name": "CDK7", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] } ] }, { "uniprot_ac": "A0A8V0Y3D1", "gene_name": "LRRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y3D1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3D1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y3D1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3D1" } ] } ] }, { "uniprot_ac": "A0A8V0Y3L2", "gene_name": "MLK4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + 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] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y7C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7C3" } ] } ] }, { "uniprot_ac": "A0A8V0Y823", "gene_name": "SRPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y823", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y823" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y823", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y823" } ] } ] }, { "uniprot_ac": "A0A8V0Y8X9", "gene_name": "PRKACA", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y8X9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8X9" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0A8V0Y8X9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8X9" } ] } ] }, { "uniprot_ac": "A0A8V0Y935", "gene_name": "MAST4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y935", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y935" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y935", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y935" } ] } ] }, { "uniprot_ac": "A0A8V0Y955", "gene_name": "PAK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y955", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y955" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y955", "database": "UniProtKB", "url": 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"uniprot_ac": "A0A8V0YCY4", "gene_name": "AURKB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YCY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YCY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY4" } ] } ] }, { "uniprot_ac": "A0A8V0YCY8", "gene_name": "RIOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YCY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YCY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY8" } ] } ] }, { "uniprot_ac": "A0A8V0YDH4", "gene_name": "ALPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YDH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDH4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YDH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDH4" } ] } ] }, { "uniprot_ac": "A0A8V0YDQ1", "gene_name": "WWP1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YDQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDQ1" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0YDQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDQ1" } ] } ] }, { "uniprot_ac": "A0A8V0YF83", "gene_name": "WNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YF83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF83" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YF83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF83" } ] } ] }, { "uniprot_ac": "A0A8V0YFH4", "gene_name": "NRK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFH4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YFH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFH4" } ] } ] }, { "uniprot_ac": "A0A8V0YFL1", "gene_name": "CDK19", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0YFL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL1" } ] } ] }, { "uniprot_ac": "A0A8V0YFP8", "gene_name": "RIPK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFP8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YFP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFP8" } ] } ] }, { "uniprot_ac": "A0A8V0YFR6", "gene_name": "TNIK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFR6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YFR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFR6" } ] } ] }, { "uniprot_ac": "A0A8V0YGW2", "gene_name": "STK32B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YGW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGW2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YGW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGW2" } ] } ] }, { "uniprot_ac": "A0A8V0YHH2", "gene_name": "STK38L", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YHH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHH2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YHH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHH2" } ] } ] }, { "uniprot_ac": "A0A8V0YHN2", "gene_name": "RPS6KA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YHN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YHN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN2" } ] } ] }, { "uniprot_ac": "A0A8V0YIV6", "gene_name": "DYRK1A", "activity": [ { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] } ] }, { "uniprot_ac": "A0A8V0YJP9", "gene_name": "RIOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YJP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YJP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP9" } ] } ] }, { "uniprot_ac": "A0A8V0YK18", "gene_name": "CDC42BPB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YK18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YK18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK18" } ] } ] }, { "uniprot_ac": "A0A8V0YKK3", "gene_name": "MAP4K4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKK3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKK3" } ] } ] }, { "uniprot_ac": "A0A8V0YLV1", "gene_name": "MARK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YLV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLV1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YLV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLV1" } ] } ] }, { "uniprot_ac": "A0A8V0YM22", "gene_name": "MYO3AL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YM22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM22" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YM22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM22" } ] } ] }, { "uniprot_ac": "A0A8V0YM96", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YM96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM96" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YM96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM96" } ] } ] }, { "uniprot_ac": "A0A8V0YMB3", "gene_name": "STK32A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMB3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMB3" } ] } ] }, { "uniprot_ac": "A0A8V0YMN5", "gene_name": "BRAF", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YMN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YMN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN5" } ] } ] }, { "uniprot_ac": "A0A8V0YNI5", "gene_name": "NIM1K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YNI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNI5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YNI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNI5" } ] } ] }, { "uniprot_ac": "A0A8V0YNY4", "gene_name": "JAK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YNY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNY4" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0YNY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNY4" } ] } ] }, { "uniprot_ac": "A0A8V0YRC9", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] } ] }, { "uniprot_ac": "A0A8V0YRN4", "gene_name": "GAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRN4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YRN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRN4" } ] } ] }, { "uniprot_ac": "A0A8V0YSH3", "gene_name": "RPS6KA6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YSH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSH3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YSH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSH3" } ] } ] }, { "uniprot_ac": "A0A8V0YTI1", "gene_name": "TSSK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTI1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTI1" } ] } ] }, { "uniprot_ac": "A0A8V0YTL9", "gene_name": "VRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTL9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTL9" } ] } ] }, { "uniprot_ac": "A0A8V0YTN5", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTN5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTN5" } ] } ] }, { "uniprot_ac": "A0A8V0YTP2", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTP2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTP2" } ] } ] }, { "uniprot_ac": "A0A8V0YXZ5", "gene_name": "CDC42BPA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YXZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXZ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YXZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXZ5" } ] } ] }, { "uniprot_ac": "A0A8V0YYX2", "gene_name": "PAK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YYX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYX2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YYX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYX2" } ] } ] }, { "uniprot_ac": "A0A8V0YYZ3", "gene_name": "SPEG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YYZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYZ3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YYZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYZ3" } ] } ] }, { "uniprot_ac": "A0A8V0YZ74", "gene_name": "MAP2K5", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZ74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZ74" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V0YZ74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZ74" } ] } ] }, { "uniprot_ac": "A0A8V0YZF2", "gene_name": "PAK5", "activity": [ 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= O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] }, { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] } ] }, { "uniprot_ac": "A0A8V0YZV9", "gene_name": "ATR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YZV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZV9" } ] } ] }, { "uniprot_ac": "A0A8V0YZY4", "gene_name": "SBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZY4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YZY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZY4" } ] } ] }, { "uniprot_ac": "A0A8V0Z124", "gene_name": "VRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z124", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z124" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z124", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z124" } ] } ] }, { "uniprot_ac": "A0A8V0Z157", "gene_name": "MARK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] } ] }, { "uniprot_ac": "A0A8V0Z1X0", "gene_name": "MAP4K3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z1X0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1X0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z1X0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1X0" } ] } ] }, { "uniprot_ac": "A0A8V0Z283", "gene_name": "MARK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z283", "database": 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+ ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z2Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2Z3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z2Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2Z3" } ] } ] }, { "uniprot_ac": "A0A8V0Z466", "gene_name": "MAP3K19", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z466", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z466" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z466", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z466" } ] } ] }, { "uniprot_ac": "A0A8V0Z6K4", "gene_name": "PIK3R4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": 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"ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z8T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8T4" } ] } ] }, { "uniprot_ac": "A0A8V0Z927", "gene_name": "PINK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z927", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z927" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z927", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z927" } ] } ] }, { "uniprot_ac": "A0A8V0Z930", "gene_name": "CAMK2B", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z930", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z930" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": 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"activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZBZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBZ2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0ZBZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBZ2" } ] } ] }, { "uniprot_ac": "A0A8V0ZC16", "gene_name": "KALRN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZC16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC16" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZC16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC16" } ] } ] }, { "uniprot_ac": "A0A8V0ZD40", "gene_name": "CDC2L1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] } ] }, { "uniprot_ac": "A0A8V0ZD48", "gene_name": "PRKCE", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD48" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0ZD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD48" } ] } ] }, { "uniprot_ac": "A0A8V0ZD60", "gene_name": "STK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZD60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD60" } ] } ] }, { "uniprot_ac": "A0A8V0ZD70", "gene_name": "DCLK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD70" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZD70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD70" } ] } ] }, { "uniprot_ac": "A0A8V0ZDU6", "gene_name": "SRC", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZDU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDU6" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0ZDU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDU6" } ] } ] }, { "uniprot_ac": "A0A8V0ZDW9", "gene_name": "NEK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZDW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDW9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZDW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDW9" } ] } ] }, { "uniprot_ac": "A0A8V0ZFM2", "gene_name": "LMTK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZFM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFM2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZFM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFM2" } ] } ] }, { "uniprot_ac": "A0A8V0ZFP1", "gene_name": "TTBK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZFP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFP1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZFP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFP1" } ] } ] }, { "uniprot_ac": "A0A8V0ZFT3", "gene_name": "LRRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZFT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFT3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZFT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFT3" } ] } ] }, { "uniprot_ac": "A0A8V0ZGY3", "gene_name": "HIPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZGY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGY3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZGY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGY3" } ] } ] }, { "uniprot_ac": "A0A8V0ZH91", "gene_name": "WNK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZH91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH91" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZH91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH91" } ] } ] }, { "uniprot_ac": "A0A8V0ZI32", "gene_name": "STK16", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZI32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI32" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZI32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI32" } ] } ] }, { "uniprot_ac": "A0A8V0ZK64", "gene_name": "PDPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZK64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK64" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZK64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK64" } ] } ] }, { "uniprot_ac": "A0A8V0ZKA2", "gene_name": "EIF2AK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZKA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKA2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZKA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKA2" } ] } ] }, { "uniprot_ac": "A0A8V0ZKM9", "gene_name": "STK36", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZKM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKM9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZKM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKM9" } ] } ] }, { "uniprot_ac": "A0A8V0ZLU3", "gene_name": "TLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZLU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLU3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZLU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLU3" } ] } ] }, { "uniprot_ac": "A0A8V0ZMK1", "gene_name": "PIKFYVE", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] }, { "ec_number": "2.7.1.150", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] }, { "ec_number": "2.7.1.150", "activity": "", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] } ] }, { "uniprot_ac": "A0A8V0ZND5", "gene_name": "CSK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZND5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZND5" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0ZND5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZND5" } ] } ] }, { "uniprot_ac": "A0A8V0ZNP7", "gene_name": "SGK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZNP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNP7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZNP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNP7" } ] } ] }, { "uniprot_ac": "A0A8V0ZPX2", "gene_name": "ALPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZPX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPX2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZPX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPX2" } ] } ] }, { "uniprot_ac": "A0A8V0ZQJ2", "gene_name": "RPS6KB2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZQJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZQJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQJ2" } ] } ] }, { "uniprot_ac": "A0A8V0ZQT5", "gene_name": "SLC13A3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZQT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQT5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZQT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQT5" } ] } ] }, { "uniprot_ac": "A0A8V0ZRX1", "gene_name": "SETD6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZRX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRX1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZRX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRX1" } ] }, { "ec_number": "2.1.1.-", "activity": "", "evidence": [ { "id": "A0A8V0ZRX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRX1" } ] } ] }, { "uniprot_ac": "A0A8V0ZSB4", "gene_name": "SIK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZSB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSB4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZSB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSB4" } ] } ] }, { "uniprot_ac": "A0A8V0ZSN8", "gene_name": "JAK1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZSN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSN8" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0ZSN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSN8" } ] } ] }, { "uniprot_ac": "A0A8V0ZSP4", "gene_name": "PKN2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] }, { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] } ] }, { "uniprot_ac": "A0A8V0ZT63", "gene_name": "STK25", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZT63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT63" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZT63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT63" } ] } ] }, { "uniprot_ac": "A0A8V0ZUC6", "gene_name": "PAK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUC6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUC6" } ] } ] }, { "uniprot_ac": "A0A8V0ZUL0", "gene_name": "PASK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUL0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUL0" } ] } ] }, { "uniprot_ac": "A0A8V0ZUU8", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU8" } ] } ] }, { "uniprot_ac": "A0A8V0ZUU9", "gene_name": "MKNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU9" } ] } ] }, { "uniprot_ac": "A0A8V0ZWC7", "gene_name": "EIF2AK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZWC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWC7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZWC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWC7" } ] } ] }, { "uniprot_ac": "A0A8V0ZWW1", "gene_name": "MAP3K12", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZWW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWW1" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0ZWW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWW1" } ] } ] }, { "uniprot_ac": "A0A8V0ZXQ9", "gene_name": "PRKG1", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZXQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXQ9" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0A8V0ZXQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXQ9" } ] } ] }, { "uniprot_ac": "A0A8V0ZYK3", "gene_name": "PPP1CC", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZYK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYK3" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZYK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYK3" } ] } ] }, { "uniprot_ac": "A0A8V0ZYU6", "gene_name": "TNNI3K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZYU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYU6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZYU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYU6" } ] } ] }, { "uniprot_ac": "A0A8V0ZZ54", "gene_name": "BRAP", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZZ54", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZ54" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZZ54", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZ54" } ] } ] }, { "uniprot_ac": "A0A8V0ZZE4", "gene_name": "OBSCN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZZE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZE4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZZE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZE4" } ] } ] }, { "uniprot_ac": "A0A8V0ZZK5", "gene_name": "STK38", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZZK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZK5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZZK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZK5" } ] } ] }, { "uniprot_ac": "A0A8V0ZZV3", "gene_name": "MYO3B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZZV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZV3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZZV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZV3" } ] } ] }, { "uniprot_ac": "A0A8V1A069", "gene_name": "TESK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A069", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A069" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1A069", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A069" } ] } ] }, { "uniprot_ac": "A0A8V1A0W4", "gene_name": "ULK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A0W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0W4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A0W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0W4" } ] } ] }, { "uniprot_ac": "A0A8V1A0Y8", "gene_name": "MAST2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A0Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Y8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A0Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Y8" } ] } ] }, { "uniprot_ac": "A0A8V1A1P3", "gene_name": "SRPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A1P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1P3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A1P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1P3" } ] } ] }, { "uniprot_ac": "A0A8V1A1Y7", "gene_name": "CDK2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A1Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1Y7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V1A1Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1Y7" } ] } ] }, { "uniprot_ac": "A0A8V1A2T9", "gene_name": "MAP3K14", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A2T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2T9" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V1A2T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2T9" } ] } ] }, { "uniprot_ac": "A0A8V1A3T8", "gene_name": "MAST3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A3T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3T8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A3T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3T8" } ] } ] }, { "uniprot_ac": "A0A8V1A4A1", "gene_name": "CAMKK2", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4A1" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1A4A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4A1" } ] } ] }, { "uniprot_ac": "A0A8V1A4J8", "gene_name": "MAPKAPK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4J8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A4J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4J8" } ] } ] }, { "uniprot_ac": "A0A8V1A4Q4", "gene_name": "MAPK3", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Q4" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1A4Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Q4" } ] } ] }, { "uniprot_ac": "A0A8V1A4V7", "gene_name": "HIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A4V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V7" } ] } ] }, { "uniprot_ac": "A0A8V1A513", "gene_name": "DAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A513" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A513" } ] } ] }, { "uniprot_ac": "A0A8V1A675", "gene_name": "CSNK1G2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A675", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A675" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A675", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A675" } ] } ] }, { "uniprot_ac": "A0A8V1A7E0", "gene_name": "DYRK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1A7E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E0" } ] } ] }, { "uniprot_ac": "A0A8V1A7E9", "gene_name": "SIK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E9" } ] } ] }, { "uniprot_ac": "A0A8V1A7M0", "gene_name": "STK39", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M0" } ] } ] }, { "uniprot_ac": "A0A8V1A7P9", "gene_name": "DCAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] } ] }, { "uniprot_ac": "A0A8V1A9S5", "gene_name": "NUAK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A9S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9S5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A9S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9S5" } ] } ] }, { "uniprot_ac": "A0A8V1ABF3", "gene_name": "PRKAA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] } ] }, { "uniprot_ac": "A0A8V1ABP4", "gene_name": "DSTYK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP4" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1ABP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP4" } ] } ] }, { "uniprot_ac": "A0A8V1ABR8", "gene_name": "CAMK4L", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR8" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1ABR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR8" } ] } ] }, { "uniprot_ac": "A0A8V1AC40", "gene_name": "CDK18", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AC40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC40" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V1AC40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC40" } ] } ] }, { "uniprot_ac": "A0A8V1ACB5", "gene_name": "MAPK13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACB5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1ACB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACB5" } ] } ] }, { "uniprot_ac": "A0A8V1ACF6", "gene_name": "PIM1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF6" } ] } ] }, { "uniprot_ac": "A0A8V1ACK0", "gene_name": "MAPKAPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK0" } ] } ] }, { "uniprot_ac": "A0A8V1ACW2", "gene_name": "WNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACW2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACW2" } ] } ] }, { "uniprot_ac": "A0A8V1ADF0", "gene_name": "MAP2K2", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF0" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V1ADF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF0" } ] } ] }, { "uniprot_ac": "A0A8V1ADN9", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADN9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1ADN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADN9" } ] } ] }, { "uniprot_ac": "A0A8V1ADT4", "gene_name": "MKNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADT4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ADT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADT4" } ] } ] }, { "uniprot_ac": "A0A8V1AE45", "gene_name": "ERN1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AE45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE45" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AE45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE45" } ] } ] }, { "uniprot_ac": "A0A8V1AEH4", "gene_name": "STK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEH4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEH4" } ] } ] }, { "uniprot_ac": "A0A8V1AFS4", "gene_name": "STKLD1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AFS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFS4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AFS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFS4" } ] } ] }, { "uniprot_ac": "A0A8V1AG70", "gene_name": "LOC100857512", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AG70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG70" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AG70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG70" } ] } ] }, { "uniprot_ac": "A0A8V1AH12", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AH12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH12" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AH12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH12" } ] } ] }, { "uniprot_ac": "A0A8V1AHA8", "gene_name": "NEK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AHA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHA8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AHA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHA8" } ] } ] }, { "uniprot_ac": "A0A8V1AIY7", "gene_name": "AATK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AIY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AIY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIY7" } ] } ] }, { "uniprot_ac": "A0A8V1AJA4", "gene_name": "RPS6KB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AJA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJA4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AJA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJA4" } ] } ] }, { "uniprot_ac": "A0A8V1AKW4", "gene_name": "MAP2K4", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AKW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKW4" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V1AKW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKW4" } ] } ] }, { "uniprot_ac": "A0A8V1AM12", "gene_name": "GSG2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AM12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM12" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AM12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM12" } ] } ] }, { "uniprot_ac": "A0A8V1AMK5", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AMK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V1AMK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK5" } ] } ] }, { "uniprot_ac": "A0A8V1AMQ2", "gene_name": "CAMKK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AMQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ2" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1AMQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ2" } ] } ] }, { "uniprot_ac": "A0A8V1AP60", "gene_name": "KSR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AP60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AP60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP60" } ] } ] }, { "uniprot_ac": "E1BQN6", "gene_name": "PRKCZ", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQN6" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1BQN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQN6" } ] } ] }, { "uniprot_ac": "E1BQV7", "gene_name": "SLK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQV7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BQV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQV7" } ] } ] }, { "uniprot_ac": "E1BS97", "gene_name": "PAK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BS97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BS97" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BS97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BS97" } ] } ] }, { "uniprot_ac": "E1BUG0", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] } ] }, { "uniprot_ac": "E1BW33", "gene_name": "SMG1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BW33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BW33" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BW33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BW33" } ] } ] }, { "uniprot_ac": "E1BWA3", "gene_name": "PRKCI", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BWA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWA3" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1BWA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWA3" } ] } ] }, { "uniprot_ac": "E1BWT0", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BWT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWT0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BWT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWT0" } ] } ] }, { "uniprot_ac": "E1BX69", "gene_name": "EIF2AK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BX69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BX69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BX69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BX69" } ] } ] }, { "uniprot_ac": "E1BY69", "gene_name": "PIM3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BY69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BY69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY69" } ] } ] }, { "uniprot_ac": "E1BYH2", "gene_name": "TAOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BYH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYH2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BYH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYH2" } ] } ] }, { "uniprot_ac": "E1C093", "gene_name": "PIK3CG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] } ] }, { "uniprot_ac": "E1C2I2", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C2I2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2I2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C2I2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2I2" } ] } ] }, { "uniprot_ac": "E1C3P6", "gene_name": "PAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C3P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C3P6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C3P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C3P6" } ] } ] }, { "uniprot_ac": "E1C581", "gene_name": "TBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C581", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C581" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C581", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C581" } ] } ] }, { "uniprot_ac": "E1C6T4", "gene_name": "PRKD3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C6T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C6T4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1C6T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C6T4" } ] } ] }, { "uniprot_ac": "E1C764", "gene_name": "BMP2K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C764", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C764" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C764", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C764" } ] } ] }, { "uniprot_ac": "E1C848", "gene_name": "MAP3K8", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C848", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C848" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1C848", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C848" } ] } ] }, { "uniprot_ac": "F1NA68", "gene_name": "CDK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NA68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NA68" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1NA68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NA68" } ] } ] }, { "uniprot_ac": "F1NB57", "gene_name": "PLK2", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NB57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NB57" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "F1NB57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NB57" } ] } ] }, { "uniprot_ac": "F1NBT0", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NBT0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NBT0" } ] } ] }, { "uniprot_ac": "F1NCX7", "gene_name": "PLK1", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NCX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCX7" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "F1NCX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCX7" } ] } ] }, { "uniprot_ac": "F1NCY7", "gene_name": "MAPKAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NCY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NCY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCY7" } ] } ] }, { "uniprot_ac": "F1NJH1", "gene_name": "PRKCH", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NJH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJH1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1NJH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJH1" } ] } ] }, { "uniprot_ac": "F1NKW3", "gene_name": "MAP3K15", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NKW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NKW3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1NKW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NKW3" } ] } ] }, { "uniprot_ac": "F1NLR7", "gene_name": "CLK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NLR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLR7" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "F1NLR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLR7" } ] } ] }, { "uniprot_ac": "F1NSA8", "gene_name": "RAP1A", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "F1NSA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NSA8" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "F1NSA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NSA8" } ] } ] }, { "uniprot_ac": "F1NUX4", "gene_name": "MTOR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NUX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NUX4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NUX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NUX4" } ] } ] }, { "uniprot_ac": "F1NVF2", "gene_name": "MAP2K6", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NVF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVF2" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "F1NVF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVF2" } ] } ] }, { "uniprot_ac": "F1P011", "gene_name": "CAMK2A", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1P011", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P011" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F1P011", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P011" } ] } ] }, { "uniprot_ac": "F1P356", "gene_name": "NUAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1P356", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P356" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1P356", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P356" } ] } ] }, { "uniprot_ac": "F1P4G3", "gene_name": "HIPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1P4G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P4G3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1P4G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P4G3" } ] } ] }, { "uniprot_ac": "P05625", "gene_name": "RAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05625", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05625" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P05625", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05625" } ] } ] }, { "uniprot_ac": "P08642", "gene_name": "HRAS", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "P08642", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P08642" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "P08642", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P08642" } ] } ] }, { "uniprot_ac": "P10741", "gene_name": "MOS", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P10741", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P10741" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P10741", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P10741" } ] } ] }, { "uniprot_ac": "P13863", "gene_name": "CDK1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13863" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13863" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13863" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13863" } ] } ] }, { "uniprot_ac": "P18652", "gene_name": "RPS6KA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P18652", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18652" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P18652", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18652" } ] } ] }, { "uniprot_ac": "P21868", "gene_name": "CSNK2A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P21868", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21868" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P21868", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21868" } ] } ] }, { "uniprot_ac": "P21869", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P21869", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21869" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P21869", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21869" } ] } ] }, { "uniprot_ac": "P53478", "gene_name": "", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "P53478", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P53478" } ] } ] }, { "uniprot_ac": "P53666", "gene_name": "LIMK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P53666", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P53666" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P53666", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P53666" } ] } ] }, { "uniprot_ac": "P62207", "gene_name": "PPP1CB", "activity": [ { "ec_number": "3.1.3.53", "activity": "O-phospho-L-threonyl-[myosin light chain] + H2O = L-threonyl-[myosin light chain] + phosphate.", "evidence": [ { "id": "P62207", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P62207" } ] }, { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P62207", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P62207" } ] }, { "ec_number": "3.1.3.53", "activity": "", "evidence": [ { "id": "P62207", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P62207" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P62207", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P62207" } ] } ] }, { "uniprot_ac": "P67962", "gene_name": "CSNK1A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P67962", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67962" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P67962", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67962" } ] } ] }, { 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"count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 9 }, { "field": "total_sites", "count": 9 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 10 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "Q4KWZ6-1", "uniprot_ac": "Q4KWZ6", "uniprot_id": "MD2L2_CHICK", "mass": { "chemical_mass": 24346.0, "monoisotopic_mass": 24346.0 }, "refseq": { "ac": "NP_001020749", "name": "mitotic spindle assembly checkpoint protein MAD2B", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001020749" }, "gene_names": [ { "name": "MAD2L2", "type": "recommended", "evidence": [ { "id": "Q4KWZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q4KWZ6" } ] }, { "name": "MAD2L2", "type": "synonym", "evidence": [ { "id": "NP_001020749", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001020749" } ] }, { "name": "REV7", "type": "synonym", "evidence": [ { "id": "NP_001020749", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001020749" }, { "id": "Q4KWZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q4KWZ6" } ] } ], "protein_names": [ { "name": "Mitotic spindle assembly checkpoint protein MAD2B", "type": "recommended", "evidence": [ { "id": "Q4KWZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q4KWZ6/entry#names_and_taxonomy" } ] }, { "name": "MAD2 homolog", "type": "synonym", "evidence": [ { "id": "NP_001020749", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001020749" } ] }, { "name": "MAD2 mitotic arrest deficient-like 2", "type": "synonym", "evidence": [ { "id": "NP_001020749", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001020749" } ] }, { "name": "MAD2-like protein 2", "type": "synonym", "evidence": [ { "id": "NP_001020749", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001020749" }, { "id": "Q4KWZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q4KWZ6/entry#names_and_taxonomy" } ] }, { "name": "Mitotic arrest deficient 2-like protein 2", "type": "synonym", "evidence": [ { "id": "Q4KWZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q4KWZ6/entry#names_and_taxonomy" } ] }, { "name": "mitotic arrest deficient 2-like protein 2", "type": "synonym", "evidence": [ { "id": "NP_001020749", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001020749" } ] }, { "name": "mitotic spindle assembly checkpoint protein MAD2B", "type": "synonym", "evidence": [ { "id": "NP_001020749", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001020749" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: HAEL01000950.1, HAEK01113013.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000329.1. On Jul 18, 2005 this sequence version replaced XP_417648.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001020749", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001020749" } ] }, { "annotation": "Adapter protein able to interact with different proteins and involved in different biological processes. Mediates the interaction between the error-prone DNA polymerase zeta catalytic subunit REV3L and the inserter polymerase REV1, thereby mediating the second polymerase switching in translesion DNA synthesis. Translesion DNA synthesis releases the replication blockade of replicative polymerases, stalled in presence of DNA lesions. May also play a role in signal transduction in response to DNA damage. May regulate the activation of the anaphase promoting complex APC thereby regulating progression through the cell cycle. Component of the shieldin complex, which plays an important role in repair of DNA double-stranded breaks (DSBs). During G1 and S phase of the cell cycle, the complex functions downstream of TP53BP1 to promote non-homologous end joining (NHEJ) and suppress DNA end resection (By similarity). Through transcriptional regulation may play a role in epithelial-mesenchymal transdifferentiation.", "evidence": [ { "database": "UniProtKB", "id": "Q4KWZ6", "url": "https://www.uniprot.org/uniprotkb/Q4KWZ6#function" }, { "database": "PubMed", "id": "20164194", "url": "https://glygen.org/publication/PubMed/20164194" }, { "database": "PubMed", "id": "15988022", "url": "https://glygen.org/publication/PubMed/15988022" }, { "database": "UniProtKB", "id": "Q9UI95", "url": "https://www.uniprot.org/uniprotkb/Q9UI95#function" } ] }, { "annotation": "Present study proves that polymerase zeta is a critical factor for tolerating nitric oxide (NO) toxicity and prevents chromosomal breaks probably by releasing replication block at NO-damaged template strands", "evidence": [ { "database": "RefSeq", "id": "NP_001020749", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001020749" }, { "database": "PubMed", "id": "16424005", "url": "https://glygen.org/publication/PubMed/16424005" } ] } ], "disease": [], "snv": [], "mutagenesis": [ { "start_pos": 171, "end_pos": 171, "sequence_org": "W", "sequence_mut": "A", "comment": "Loss of function in DNA repair; when associated with Y-63.", "evidence": [ { "database": "UniProtKB", "id": "Q4KWZ6", "url": "https://www.uniprot.org/uniprotkb/Q4KWZ6" }, { "database": "PubMed", "id": "20164194", "url": "https://glygen.org/publication/PubMed/20164194" } ] }, { "start_pos": 63, "end_pos": 63, "sequence_org": "Y", "sequence_mut": "A", "comment": "Loss of function in DNA repair; when associated with W-171.", "evidence": [ { "database": "UniProtKB", "id": "Q4KWZ6", "url": "https://www.uniprot.org/uniprotkb/Q4KWZ6" }, { "database": "PubMed", "id": "20164194", "url": "https://glygen.org/publication/PubMed/20164194" } ] } ], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q4KWZ6", "url": "https://www.uniprot.org/uniprotkb/Q4KWZ6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MAD2L2", "url": "https://www.uniprot.org/uniprotkb/Q4KWZ6", "locus": { "chromosome": "21", "start_pos": 5655297, "end_pos": 5649727, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021207", "url": "https://www.ensembl.org/id/ENSGALG00010021207" } ] } } ], "crossref": [ { "id": "Q4KWZ6", "url": "https://alphafold.ebi.ac.uk/entry/Q4KWZ6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000004640", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000004640", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "419493", "url": "https://www.ncbi.nlm.nih.gov/gene/419493", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003511", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003511", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036570", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036570", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045091", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045091", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:419493", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419493", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CEDFPWI", "url": "https://omabrowser.org/oma/group/CEDFPWI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A452J817", "url": "https://www.orthodb.org/?gene=A0A452J817", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZIG4", "url": "https://www.orthodb.org/?gene=A0A8V0ZIG4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZPE5", "url": "https://www.orthodb.org/?gene=A0A8V0ZPE5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "Q4KWZ6", "url": "https://www.orthodb.org/?gene=Q4KWZ6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11842", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11842", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11842:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11842:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02301", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02301", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q4KWZ6", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q4KWZ6", "database": "PRO", "categories": [ "Protein" ] }, { "id": "R-GGA-110312", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-110312", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-353299", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-353299", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-353473", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-353473", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5655862", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5655862", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5656121", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5656121", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5656169", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5656169", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001020749", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001020749", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A452J817", "url": "https://www.uniprot.org/uniprotkb/A0A452J817", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A452J817-1", "url": "https://www.uniprot.org/uniprotkb/A0A452J817-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIG4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIG4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIG4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIG4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZPE5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPE5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZPE5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPE5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q4KWZ6", "url": "https://www.uniprot.org/uniprotkb/Q4KWZ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q4KWZ6-1", "url": "https://www.uniprot.org/uniprotkb/Q4KWZ6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTTLTRQDLNFGQVVADVLSEFLEVAVHLILYVREVYPIGIFQKRKKYNVPVQMSCHPELNQYIQDTLHCVKPLLEKNDVEKVVVVILDKEHHPVERFVFEITQPPLLSISSESLLSHVEQLLRAFILKISVCDAVLDNNPPGCTFTVLVHTREAATRNMEKIQVIKDFPWILADEQDVHMHDPRLIPLKTMTSDILKMQLYVEERAHKGT", "length": 211, "header": "sp|Q4KWZ6-1|MD2L2_CHICK Isoform 1 of Mitotic spindle assembly checkpoint protein MAD2B OS=Gallus gallus OX=9031 GN=MAD2L2 PE=1 SV=1 CANONICAL=Q4KWZ6-1" }, "isoforms": [ { "isoform_ac": "A0A452J817-1", "url": "https://www.uniprot.org/uniprotkb/Q4KWZ6/entry#A0A452J817-1", "sequence": { "sequence": "RSLPYWDLSEEKKIQRTRPDVLPPRAQSVHPGHVALCKATAREDIVLHVEPGSRTGLKNDVEKVVVVILDKEHHPVERFVFEITQPPLLSISSESLLSHVEQLLRAFILKISVCDAVLDNNPPGCTFTVLVHTREAATRNMEKIQVIKDFPWILADEQDVHMHDPRLIPLKTMTSDILKMQLYVEERAHKGT", "length": 192, "header": "tr|A0A452J817-1|MD2L2_CHICK Computationally mapped isoform of Mitotic spindle assembly checkpoint protein MAD2B OS=Gallus gallus OX=9031 GN=MAD2L2 PE=1 SV=1 CANONICAL=Q4KWZ6-1" }, "locus": { "chromosome": "21", "start_pos": 5654756, "end_pos": 5652655, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051386.1", "url": "https://www.ensembl.org/id/ENSGALT00010051386.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030577.1", "url": "https://www.ensembl.org/id/ENSGALP00010030577.1" } ] } }, { "isoform_ac": "A0A8V0ZIG4-1", "url": "https://www.uniprot.org/uniprotkb/Q4KWZ6/entry#A0A8V0ZIG4-1", "sequence": { "sequence": "MTTLTRQDLNFGQVVADVLSEFLEVAVHLILYVREVYPIGIFQKRKKYNVPVQMSCHPELNQYIQDTLHCVKPLLEKNDVEKVVVVILDKEHHPVERFVFEITQPPLLSISSESLLSHVEQLLRAFILKISVCDAVLDNNPPGCTFTVLVHTREAATRNMEKIQVIKDFPWILADEQDVHMHDPRLIPLKTMTSDILKVSRAFWPERWLKPHVV", "length": 214, "header": "tr|A0A8V0ZIG4-1|A0A8V0ZIG4_CHICK Computationally mapped isoform of Mitotic spindle assembly checkpoint protein MAD2B OS=Gallus gallus OX=9031 GN=MAD2L2 PE=4 SV=1 CANONICAL=Q4KWZ6-1" }, "locus": { "chromosome": "21", "start_pos": 5654581, "end_pos": 5652373, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051391.1", "url": "https://www.ensembl.org/id/ENSGALT00010051391.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030582.1", "url": "https://www.ensembl.org/id/ENSGALP00010030582.1" } ] } }, { "isoform_ac": "A0A8V0ZPE5-1", "url": "https://www.uniprot.org/uniprotkb/Q4KWZ6/entry#A0A8V0ZPE5-1", "sequence": { "sequence": "MRPRAAQRRAALSLPPLCVVLTLNPNAWDERLLLQRRGDGNRTVSTEADGRLQVLGKMTTLTRQDLNFGQVVADVLSEFLEVAVHLILYVREVYPIGIFQKRKKYNVPVQMSCHPELNQYIQDTLHCVKPLLEKNDVEKVVVVILDKEHHPVERFVFEITQPPLLSISSESLLSHVEQLLRAFILKISVCDAVLDNNPPGCTFTVLVHTREAATRNMEKIQVIKDFPWILADEQDVHMHDPRLIPLKTMTSDILKMQLYVEERAHKGT", "length": 268, "header": "tr|A0A8V0ZPE5-1|A0A8V0ZPE5_CHICK Computationally mapped isoform of Mitotic spindle assembly checkpoint protein MAD2B OS=Gallus gallus OX=9031 GN=MAD2L2 PE=4 SV=1 CANONICAL=Q4KWZ6-1" }, "locus": { "chromosome": "21", "start_pos": 5654756, "end_pos": 5649882, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051393.1", "url": "https://www.ensembl.org/id/ENSGALT00010051393.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030584.1", "url": "https://www.ensembl.org/id/ENSGALP00010030584.1" } ] } }, { "isoform_ac": "Q4KWZ6-1", "url": "https://www.uniprot.org/uniprotkb/Q4KWZ6/entry#Q4KWZ6-1", "sequence": { "sequence": "MTTLTRQDLNFGQVVADVLSEFLEVAVHLILYVREVYPIGIFQKRKKYNVPVQMSCHPELNQYIQDTLHCVKPLLEKNDVEKVVVVILDKEHHPVERFVFEITQPPLLSISSESLLSHVEQLLRAFILKISVCDAVLDNNPPGCTFTVLVHTREAATRNMEKIQVIKDFPWILADEQDVHMHDPRLIPLKTMTSDILKMQLYVEERAHKGT", "length": 211, "header": "sp|Q4KWZ6-1|MD2L2_CHICK Isoform 1 of Mitotic spindle assembly checkpoint protein MAD2B OS=Gallus gallus OX=9031 GN=MAD2L2 PE=1 SV=1 CANONICAL=Q4KWZ6-1" }, "locus": { "chromosome": "21", "start_pos": 5654756, "end_pos": 5652373, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051390.1", "url": "https://www.ensembl.org/id/ENSGALT00010051390.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030581.1", "url": "https://www.ensembl.org/id/ENSGALP00010030581.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Multiple roles of vertebrate REV genes in DNA repair and recombination.", "journal": "Molecular and cellular biology", "date": "2005", "authors": "Okada T, Sonoda E, Yoshimura M, Kawano Y, Saya H, Kohzaki M, Takeda S", "evidence": [ { "database": "UniProtKB", "id": "Q4KWZ6", "url": "https://www.uniprot.org/uniprotkb/Q4KWZ6" }, { "database": "Reactome", "id": "R-GGA-353473", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-353473" } ], "reference": [ { "type": "PubMed", "id": "15988022", "url": "https://glygen.org/publication/PubMed/15988022" } ] }, { "title": "Critical roles for polymerase zeta in cellular tolerance to nitric oxide-induced DNA damage.", "journal": "Cancer research", "date": "2006-01-15", "authors": "Wu Xiaohua, Takenaka Katsuya, Sonoda Eiichiro, Hochegger Helfrid, Kawanishi Shosuke, Kawamoto 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The reference sequence was derived from JAENSK010000043.1. On Sep 23, 2021 this sequence version replaced NP_989808.2.", "evidence": [ { "database": "RefSeq", "id": "NP_989808", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989808" } ] }, { "annotation": "Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0X2H3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X2H3#function" }, { "database": "UniProtKB", "id": "RU368072", "url": "https://www.uniprot.org/uniprotkb/RU368072#function" }, { "database": "UniProtKB", "id": "A0A8V0X5K2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X5K2#function" }, { "database": "UniProtKB", "id": "A0A8V0XBA5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XBA5#function" }, { "database": "UniProtKB", "id": "A0A8V0XBF4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XBF4#function" }, { "database": "UniProtKB", "id": "Q76I89", "url": "https://www.uniprot.org/uniprotkb/Q76I89#function" }, { "database": "UniProtKB", "id": "O14777", "url": "https://www.uniprot.org/uniprotkb/O14777#function" }, { "database": "PubMed", "id": "12829748", "url": "https://glygen.org/publication/PubMed/12829748" } ] }, { "annotation": "Recruitment of two Ndc80 complexes via the CENP-T pathway is sufficient for kinetochore functions. Publication Status: Online-Only", "evidence": [ { "database": "RefSeq", "id": "NP_989808", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989808" }, { "database": "PubMed", "id": "35165266", "url": "https://glygen.org/publication/PubMed/35165266" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q76I89", "url": "https://www.uniprot.org/uniprotkb/Q76I89" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NDC80", "url": "https://www.uniprot.org/uniprotkb/Q76I89", "locus": { "chromosome": "2", "start_pos": 100795194, "end_pos": 100814091, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010001457", "url": "https://www.ensembl.org/id/ENSGALG00010001457" } ] } } ], "crossref": [ { "id": "Q76I89", "url": "https://alphafold.ebi.ac.uk/entry/Q76I89", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000014801", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000014801", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "395134", "url": "https://www.ncbi.nlm.nih.gov/gene/395134", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "Q76I89", "url": "https://www.ebi.ac.uk/intact/interactors/id:Q76I89*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "IPR005550", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005550", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038273", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038273", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040967", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040967", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055260", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055260", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057091", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057091", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:395134", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395134", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PSHKFQK", "url": "https://omabrowser.org/oma/group/PSHKFQK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0X2H3", "url": "https://www.orthodb.org/?gene=A0A8V0X2H3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0X5K2", "url": "https://www.orthodb.org/?gene=A0A8V0X5K2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XBA5", "url": "https://www.orthodb.org/?gene=A0A8V0XBA5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XBF4", "url": "https://www.orthodb.org/?gene=A0A8V0XBF4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "Q76I89", "url": "https://www.orthodb.org/?gene=Q76I89", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10643", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10643", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10643:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10643:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03801", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03801", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18077", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18077", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24487", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24487", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q76I89", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q76I89", "database": "PRO", "categories": [ "Protein" ] }, { "id": "R-GGA-141430", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-141430", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-141444", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-141444", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-2467813", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2467813", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-2500257", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2500257", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5663220", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5663220", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9648025", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9648025", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_989808", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989808", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0X2H3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X2H3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0X2H3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X2H3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0X5K2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X5K2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0X5K2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X5K2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XBA5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XBA5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XBA5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XBA5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XBF4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XBF4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XBF4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XBF4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q76I89", "url": "https://www.uniprot.org/uniprotkb/Q76I89", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q76I89-1", "url": "https://www.uniprot.org/uniprotkb/Q76I89-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRRSSTTSGSSGRQSTMVLRVQDSNKMGLQTPQTKDRGTFGKLSMSKTTSATSERKVSFFGKRASGAGGSRNSQYGMFGTEKIKDPRPLHDKAFIQQCIKQLCEFLVENGYAHNVTIKSLQSPSVKDFIKIFTFIYGFLCPSYELPDSKFEEEIPRVFKELGYPFPLSKSSMYTVGAPHTWPQIVAALIWLTDCFKLYAAMRENPSSFDDGQNWGGETDDGIVHNKLFMDYVVKCYEHFMKGGDTYEELDAEVQSKLKDLFNVDEFKIEGLAAENKRLHEEIARLEKERESEPDRLVSLRKLRSSFQADVQKYQAYLANLESHTTILDQKMKSVNEEVETTEMEVEAMKQENARLQHIFDNQKYSVADIERINHERNELQQTINKLTKELEAEEHQLWNEELKYARNKEAIETQLAEYHKLARKLKLIPISAENSKGHDFEIHFNPEAGPNCLVKYRTQIKAPLMEIVNQTEEEIRKATQRKMSLEDTLEQVNAMVAEKKSSVKTLKEEAEKLDDLYHQKLKEAEEEEQKCANELELLEKHKQLLESGVNEGLSEATNELHDIQRQYQIVMQTTTEESRKAGDNLNRLLEVITTHVVSIEKYLDEQNSKIDRDYEEFMSEDLLSTLTGILDSYKKKAESI", "length": 640, "header": "sp|Q76I89-1|NDC80_CHICK Isoform 1 of Kinetochore protein NDC80 homolog OS=Gallus gallus OX=9031 GN=NDC80 PE=1 SV=1 CANONICAL=Q76I89-1" }, "isoforms": [ { "isoform_ac": "A0A8V0X2H3-1", "url": "https://www.uniprot.org/uniprotkb/Q76I89/entry#A0A8V0X2H3-1", "sequence": { "sequence": "MRRSSTTSGSSGRQSTMVLRVQDSNKMGLQTPQTKDRGTFGKLSMSKTTSATSERKVSFFGKRASGAGGSRNSQYGMFGTEKIKDPRPLHDKAFIQQCIKQLCEFLVENGYAHNVTIKSLQSPSVKDFIKIFTFIYGFLCPSYELPDSKFEEEIPRVFKELGYPFPLSKSSMYTVGAPHTWPQIVAALIWLTDCFKLYAAMRENPSSFDDGQNWGGETDDGIVHNKLFMDYVVKCYEHFMKGGDTYEELDAEVQSKLKDLFNVDEFKIEGLAAENKRLHEEIARLEKERESEPDRLVSLRKLRSSFQADVQKYQAYLANLESHTTILDQKMKSVNEEVETTEMEVEAMKQENARLQHIFDNQKYSVADIERINHERNELQQTINKLTKELEAEEHQLWNEELKYARNKEAIETQLAEYHKLARKLKLIPISAENSKGHDFEIHFNPEAGPNCLVKYRTQIKAPLMEIVNQTEEEIRKATQRKMSLEDTLEQVNAMVAEKKSSVKTLKEEAEKLDDLYHQKLKEAEEEEQKCANELELLEKHKQLLESGVNEGLSEATNELHDIQRHGARLFSVVPSARTRDNGCKL", "length": 586, "header": "tr|A0A8V0X2H3-1|NDC80_CHICK Computationally mapped isoform of Kinetochore protein NDC80 homolog OS=Gallus gallus OX=9031 GN=NDC80 PE=1 SV=1 CANONICAL=Q76I89-1" }, "locus": { "chromosome": "2", "start_pos": 100813596, "end_pos": 100799440, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010003368.1", "url": "https://www.ensembl.org/id/ENSGALT00010003368.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010001811.1", "url": "https://www.ensembl.org/id/ENSGALP00010001811.1" } ] } }, { "isoform_ac": "A0A8V0X5K2-1", "url": "https://www.uniprot.org/uniprotkb/Q76I89/entry#A0A8V0X5K2-1", "sequence": { "sequence": "MRRSSTTSGSSGRQSTMVLRVQDSNKMGLQTPQTKDRGTFGKLSMSKTTSATSERKVSFFGKRASGAGGSRNSQYGMFGTEKIKDPRPLHDKAFIQQCIKQLCEFLVENGYAHNVTIKSLQSPSVKDFIKIFTFIYGFLCPSYELPDSKFEEEIPRVFKELGYPFPLSKSSMYTVGAPHTWPQIVAALIWLTDCFKVAFEFFIPNISTFQAGILVTDVLILFMDYVVKCYEHFMKGGDTYEELDAEVQSKLKDLFNVDEFKIEGLAAENKRLHEEIARLEKERESEPDRLVSLRKLRSSFQADVQKYQAYLANLESHTTILDQKMKSVNEEVETTEMEVEAMKQENARLQHIFDNQKYSVADIERINHERNELQQTINKLTKELEAEEHQLWNEELKYARNKEAIETQLAEYHKLARKLKLIPISAENSKGHDFEIHFNPEAGPNCLVKYRTQIKAPLMEIVNQTEEEIRKATQRKMSLEDTLEQVNAMVAEKKSSVKTLKEEAEKLDDLYHQKLKEAEEEEQKCANELELLEKHKQLLESGVNEGLSEATNELHDIQRQYQIVMQTTTEESRKAGDNLNRLLEVITTHVVSIEKYLDEQNSKIDRDYEEFMSEDLLSTLTGILDSYKKKAESI", "length": 634, "header": "tr|A0A8V0X5K2-1|NDC80_CHICK Computationally mapped isoform of Kinetochore protein NDC80 homolog OS=Gallus gallus OX=9031 GN=NDC80 PE=1 SV=1 CANONICAL=Q76I89-1" }, "locus": { "chromosome": "2", "start_pos": 100813596, "end_pos": 100797350, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010003373.1", "url": "https://www.ensembl.org/id/ENSGALT00010003373.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010001816.1", "url": "https://www.ensembl.org/id/ENSGALP00010001816.1" } ] } }, { "isoform_ac": "A0A8V0XBA5-1", "url": "https://www.uniprot.org/uniprotkb/Q76I89/entry#A0A8V0XBA5-1", "sequence": { "sequence": "MRRSSTTSGSSGRQSTMVLRVQDSNKMGLQTPQTKDRGTFGKLSMSKTTSATSERKVSFFGKRASGAGGSRNSQYGMFGTEKIKDPRPLHDKAFIQQCIKQLCEFLVENGYAHNVTIKSLQSPSVKDFIKIFTFIYGFLCPSYELPDSKFEEEIPRVFKELGYPFPLSKSSMYTVGAPHTWPQIVAALIWLTDCFKLYAAMRENPSSFDDGQNWGGETDDGIVHNKLFMDYVVKCYEHFMKGGDTYEELDAEVQSKLKDLFNVDEFKIEGLAAENKRLHEEIARLEKERESEPDRLVSLRKLRSSFQADVQKYQAYLANLESHTTILDQKMKSVNEEVETTEMEVEAMKQENARLQHIFDNQKYSVADIERINHERNELQQTINKLTKELEAEEHQLWNEELKYARNKEAIETQLAEYHKLARKLKLIPISAENSKGHDFEIHFNPEAGPNCLVKYRTQIKAPLMEIVNQTEEEIRKATQRKMSLEDTLEQVNAMVAEKKSSVKTLKEEAEKLDDLYHQKLKEAEEEEQKCANELELLEKHKQLLESGVNEGLSEATNELHDIQRQYQIVMQTTTEESRKAGDNLNRLLEVITTHVVSIERNTLMNRIQKLTETMKNSCLKIFCQP", "length": 626, "header": "tr|A0A8V0XBA5-1|NDC80_CHICK Computationally mapped isoform of Kinetochore protein NDC80 homolog OS=Gallus gallus OX=9031 GN=NDC80 PE=1 SV=1 CANONICAL=Q76I89-1" }, "locus": { "chromosome": "2", "start_pos": 100813596, "end_pos": 100797394, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010003371.1", "url": "https://www.ensembl.org/id/ENSGALT00010003371.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010001814.1", "url": "https://www.ensembl.org/id/ENSGALP00010001814.1" } ] } }, { "isoform_ac": "A0A8V0XBF4-1", "url": "https://www.uniprot.org/uniprotkb/Q76I89/entry#A0A8V0XBF4-1", "sequence": { "sequence": "MRRSSTTSGSSGRQSTMVLRVQDSNKMGLQTPQTKDRGTFGKLSMSKTTSATSERKVSFFGKRASGAGGSRNSQYGMFGTEKIKDPRPLHDKAFIQQCIKQLCEFLVENGYAHNVTIKSLQSPSVKDFIKIFTFIYGFLCPSYELPDSKFEEEIPRVFKELGYPFPLSKSSMYTVGAPHTWPQIVAALIWLTDCFKLYAAMRENPSSFDDGQNWGGETDDGIVHNKLFMDYVVKCYEHFMKGGDTYEELDAEVQSKLKDLFNVDEFKIEGLAAENKRLHEEIARLEKERESEPDRLVSLRKLRSSFQADVQKYQAYLANLESHTTILDQKMKSVNEEVETTEMEVEAMKQENARLQHIFDNQKYSVADIERINHERNELQQTINKLTKELEAEEHQLWNEELKYARNKEAIETQLAEYHKLARKLKLIPISAENSKGHDFEIHFNPEAGPNCLVKYRTQIKVNAMVAEKKSSVKTLKEEAEKLDDLYHQKLKEAEEEEQKCANELELLEKHKQLLESGVNEGLSEATNELHDIQRQYQIVMQTTTEESRKAGDNLNRLLEVITTHVVSIEKYLDEQNSKIDRDYEEFMSEDLLSTLTGILDSYKKKAESI", "length": 610, "header": "tr|A0A8V0XBF4-1|NDC80_CHICK Computationally mapped isoform of Kinetochore protein NDC80 homolog OS=Gallus gallus OX=9031 GN=NDC80 PE=1 SV=1 CANONICAL=Q76I89-1" }, "locus": { "chromosome": "2", "start_pos": 100813596, "end_pos": 100797350, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010003375.1", "url": "https://www.ensembl.org/id/ENSGALT00010003375.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010001818.1", "url": "https://www.ensembl.org/id/ENSGALP00010001818.1" } ] } }, { "isoform_ac": "Q76I89-1", "url": "https://www.uniprot.org/uniprotkb/Q76I89/entry#Q76I89-1", "sequence": { "sequence": "MRRSSTTSGSSGRQSTMVLRVQDSNKMGLQTPQTKDRGTFGKLSMSKTTSATSERKVSFFGKRASGAGGSRNSQYGMFGTEKIKDPRPLHDKAFIQQCIKQLCEFLVENGYAHNVTIKSLQSPSVKDFIKIFTFIYGFLCPSYELPDSKFEEEIPRVFKELGYPFPLSKSSMYTVGAPHTWPQIVAALIWLTDCFKLYAAMRENPSSFDDGQNWGGETDDGIVHNKLFMDYVVKCYEHFMKGGDTYEELDAEVQSKLKDLFNVDEFKIEGLAAENKRLHEEIARLEKERESEPDRLVSLRKLRSSFQADVQKYQAYLANLESHTTILDQKMKSVNEEVETTEMEVEAMKQENARLQHIFDNQKYSVADIERINHERNELQQTINKLTKELEAEEHQLWNEELKYARNKEAIETQLAEYHKLARKLKLIPISAENSKGHDFEIHFNPEAGPNCLVKYRTQIKAPLMEIVNQTEEEIRKATQRKMSLEDTLEQVNAMVAEKKSSVKTLKEEAEKLDDLYHQKLKEAEEEEQKCANELELLEKHKQLLESGVNEGLSEATNELHDIQRQYQIVMQTTTEESRKAGDNLNRLLEVITTHVVSIEKYLDEQNSKIDRDYEEFMSEDLLSTLTGILDSYKKKAESI", "length": 640, "header": "sp|Q76I89-1|NDC80_CHICK Isoform 1 of Kinetochore protein NDC80 homolog OS=Gallus gallus OX=9031 GN=NDC80 PE=1 SV=1 CANONICAL=Q76I89-1" }, "locus": { "chromosome": "2", "start_pos": 100813596, "end_pos": 100797350, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010003372.1", "url": "https://www.ensembl.org/id/ENSGALT00010003372.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010001815.1", "url": "https://www.ensembl.org/id/ENSGALP00010001815.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Dynamic behavior of Nuf2-Hec1 complex that localizes to the centrosome and centromere and is essential for mitotic progression in vertebrate cells.", "journal": "Journal of cell science", "date": "2003-08-15", "authors": "Hori Tetsuya, Haraguchi Tokuko, Hiraoka Yasushi, Kimura Hiroshi, Fukagawa Tatsuo", "evidence": [ { "database": "UniProtKB", "id": "Q76I89", "url": "https://www.uniprot.org/uniprotkb/Q76I89" } ], "reference": [ { "type": "PubMed", "id": "12829748", "url": "https://glygen.org/publication/PubMed/12829748" } ] }, { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q76I89", "url": "https://www.uniprot.org/uniprotkb/Q76I89" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] }, { "title": "The functional region of CENP-H interacts with the Nuf2 complex that localizes to centromere during mitosis.", "journal": "Mol. Cell. Biol.", "date": "2005", "authors": "Mikami Y, Hori T, Kimura H, Fukagawa T", "evidence": [ { "database": "UniProtKB", "id": "Q76I89", "url": "https://www.uniprot.org/uniprotkb/Q76I89" } ], "reference": [ { "type": "PubMed", "id": "15713649", "url": "https://glygen.org/publication/PubMed/15713649" } ] }, { "title": "CENP-A is required for accurate chromosome segregation and sustained kinetochore association of BubR1.", "journal": "Mol. Cell. Biol.", "date": "2005", "authors": "R\u00e9gnier Vinciane, Vagnarelli Paola, Fukagawa Tatsuo, Zerjal Tatiana, Burns Elizabeth, Trouche Didier, Earnshaw William, Brown William", "evidence": [ { "database": "UniProtKB", "id": "Q76I89", "url": "https://www.uniprot.org/uniprotkb/Q76I89" } ], "reference": [ { "type": "PubMed", "id": "15870271", "url": "https://glygen.org/publication/PubMed/15870271" } ] }, { "title": "Spindle microtubules generate tension-dependent changes in the distribution of inner kinetochore proteins.", "journal": "J. Cell Biol.", "date": "2011", "authors": "Suzuki Aussie, Hori Tetsuya, Nishino Tatsuya, Usukura Jiro, Miyagi Atsushi, Morikawa Kosuke, Fukagawa Tatsuo", "evidence": [ { "database": "UniProtKB", "id": "Q76I89", "url": "https://www.uniprot.org/uniprotkb/Q76I89" } ], "reference": [ { "type": "PubMed", "id": "21464230", "url": "https://glygen.org/publication/PubMed/21464230" } ] }, { "title": "Recruitment of two Ndc80 complexes via the CENP-T pathway is sufficient for kinetochore functions.", "journal": "Nature communications", "date": "2022-02-14", "authors": "Takenoshita Yusuke, Hara Masatoshi, Fukagawa Tatsuo", "evidence": [ { "database": "RefSeq", "id": "NP_989808", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989808" } ], "reference": [ { "type": "PubMed", "id": "35165266", "url": "https://glygen.org/publication/PubMed/35165266" } ] } ], "pathway": [ { "id": "gga:395134", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395134", "resource": "KEGG Pathway" }, { "id": "R-GGA-141430", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-141430", "resource": "Reactome", "description": "Inactivation of APC/C via direct inhibition of the APC/C complex" }, { "id": "R-GGA-141444", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-141444", "resource": "Reactome", "description": "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" }, { "id": "R-GGA-2467813", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2467813", "resource": "Reactome", "description": "Separation of Sister Chromatids" }, { "id": "R-GGA-2500257", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2500257", "resource": "Reactome", "description": "Resolution of Sister Chromatid Cohesion" }, { "id": "R-GGA-5663220", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5663220", "resource": "Reactome", "description": "RHO GTPases Activate Formins" }, { "id": "R-GGA-9648025", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9648025", "resource": "Reactome", "description": "EML4 and NUDC in mitotic spindle formation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2K254-1", "protein_name": "Kinetochore protein NDC80", "gene_name": "Ndc80", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKRSSVSSCGAGRLSMQELRSLDLNKPGLHTPQTERSTFGKLSTHKPTSERKVSIFGKRTSEHGSRNSQLGIFSSSEKIKDPRPLNDKAFIQQCIRQLYEFLTENGYVYSVSMKSLQAPSTKDFLKIFAFLYGFLCPSYELPDTKCEEEVPRIFKELGYPFALSKSSMYTVGAPHTWPHIVAALVWLTDCIKIHDAMKQSSPLFDDGQAWGEETEDGIKHNKLFLDYTKKCYEKFMTGADTFEDVDAELQAKLKDLYKVDASKLESLVEENKALNEQIARLEQEREKEPNRLISLRKLKASLQADVQNYKAYMSNLESHSSILEQKLSSLDEEIGRLELECETVKQENTRLQSVVDNQKYSIADIERINHEKNELQQTINKLTKDLEAEQQQMWNEELKYARGKEAIEAQLAEYHKLARKLKLIPKGAENSKGYDFEIKFNPEAGANCLVKYRTQVYAPLKELLNEIEEEINKALNKKMGLEDTLEQLNTVKTESKRAVRMLKEEVQKLDDLYQQKVKEAEEEDKKCASELDSLEKHKHLLESAVNEGLSEAMGELDAVQREYQLAVQTTTEERRKVGNNLQRLLEMVATHVGSLEKHLEEQIVKADREYEECTSEDLLENIRRIAEKYKSNAAQLKAPDK", "length": 641 }, "evidence": [ { "id": "Q76I89", "url": "https://omabrowser.org/oma/group/Q76I89/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1BF82-1", "protein_name": "Kinetochore protein NDC80", "gene_name": "NDC80", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MKRSSVSTGGAGRLSMQELRSQDLNKPGLHTPQTKEKSTFGKLNINRPTSERKTSVFGKRTSGPGSRNSQFGIFSTSEKIKDPRPLNDKAFIQQCIRQLCEFLSENGYAYSVSMKSLQAPSVKDFLKIFTFLYGFLCPSYELPDTKFEEEVPRIFRDLGYPFALSKSSMYTVGAPHTWPHIVAALVWLIDCIKLHNAMKESSPLFDDGQPWGEETEDGIMHNKLFLDYTIKCYESFMTGADSFEEMNAELQSKLKDLFNVDASKLESLAAKNRALNEQIARLEQEREKEPNRLESLRKLKTSLQADVQKYQAYMSNLESHSAILDQKLNGLDEEISRVELECETMKQENSRLQNIVDNQKYSVADVERINHERNELQQTINKLTKDLEAEQQQLWNEELKYARGKEAIETQLTEYHKLARKLKLIPKGAENSKGYDFEIKFNPDAGANCLVKYRAQVYAPLKELLNQTEEEINKALNKKMGLEDTLEQLSTMITESRRSVRTLKEEVQKLDDLYQQKVKEAEEEDKKCADELESLEKHKHLLESAVNEGLSEAVNELDAIQREYQLVVQTTTEERRKVGNNLQRLLEMVAIHVGSVEKHLEEQIAKNDRECKEYASEDLLENIREIGDKYKKKAALIQALDE", "length": 642 }, "evidence": [ { "id": "Q76I89", "url": "https://omabrowser.org/oma/group/Q76I89/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3HXF9-1", "protein_name": "Kinetochore protein NDC80", "gene_name": "Ndc80", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MKRSSVSTGGAGRLSIQELRSLDLNKPGLHTPQTKERTTFGKLSTNKPTSERKVSIFGKRTSGHGSRNSQLGIFSSSEKIKDPRPLNDKGFIQQCIRQLYEFLTENGNVCSVSMKSLQAPSTKDFLKIFAFLYGFLCPSYELPDTKFEEEIPRIFKDLGYPFALSKSSMYTVGAPHTWPHIVAALVWLIDCIKIHAAMKENSPLFDDMQSWGEETEDGIIHNKLFLDYTIKCYESFMTGADSFEEMNAELQSKLKDLYKVDASKLESLAAENKALNEQIARLEQEREKEPNRLISLKKLKASLQADVEKYKAYMSNLESHSSILDQKLSGLDEEIGRLELQCETIRQENTRLQNIVDNQKYSVADIERINHEKNELQQTINKLTKDLEAEQQQMWNEELKYARGKEAIEAQLAEYHKLARKLKLIPKGAENSKGHDFEIKFNPEAGAKCLVKYKAQVYVHLKELLNENEEEINKALNKKIGLEDTLEQLNTMKTETRRSVKMLKEEVQKLDDLYQQKVKEAEEEDEKCASELKSLEKHKHLLESTVKEGLREAMDELDAVQREYQLVVQTTTEERRKVGNNLQRLLEMVATHVGSLEKHLEEQIAKANREYEDCMSEDLLENIRESAEKYKSNAAVFKAPLNEDK", "length": 645 }, "evidence": [ { "id": "Q76I89", "url": "https://omabrowser.org/oma/group/Q76I89/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "O14777-1", "protein_name": "Kinetochore protein NDC80 homolog", "gene_name": "NDC80", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKRSSVSSGGAGRLSMQELRSQDVNKQGLYTPQTKEKPTFGKLSINKPTSERKVSLFGKRTSGHGSRNSQLGIFSSSEKIKDPRPLNDKAFIQQCIRQLCEFLTENGYAHNVSMKSLQAPSVKDFLKIFTFLYGFLCPSYELPDTKFEEEVPRIFKDLGYPFALSKSSMYTVGAPHTWPHIVAALVWLIDCIKIHTAMKESSPLFDDGQPWGEETEDGIMHNKLFLDYTIKCYESFMSGADSFDEMNAELQSKLKDLFNVDAFKLESLEAKNRALNEQIARLEQEREKEPNRLESLRKLKASLQGDVQKYQAYMSNLESHSAILDQKLNGLNEEIARVELECETIKQENTRLQNIIDNQKYSVADIERINHERNELQQTINKLTKDLEAEQQKLWNEELKYARGKEAIETQLAEYHKLARKLKLIPKGAENSKGYDFEIKFNPEAGANCLVKYRAQVYVPLKELLNETEEEINKALNKKMGLEDTLEQLNAMITESKRSVRTLKEEVQKLDDLYQQKIKEAEEEDEKCASELESLEKHKHLLESTVNQGLSEAMNELDAVQREYQLVVQTTTEERRKVGNNLQRLLEMVATHVGSVEKHLEEQIAKVDREYEECMSEDLSENIKEIRDKYEKKATLIKSSEE", "length": 642 }, "evidence": [ { "id": "Q76I89", "url": "https://omabrowser.org/oma/group/Q76I89/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P40460-1", "protein_name": "Kinetochore protein NDC80", "gene_name": "NDC80", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MQSSTSTDQHVLHHMDPHRFTSQIPTATSSQLRRRNSTNQGLTDMINKSIARNTISGTGIPTGGINKNKRTRSTVAGGTNGTALALNDKSNSRNSVSRLSINQLGSLQQHLSNRDPRPLRDKNFQSAIQEEIYDYLKKNKFDIETNHPISIKFLKQPTQKGFIIIFKWLYLRLDPGYGFTKSIENEIYQILKNLRYPFLESINKSQISAVGGSNWHKFLGMLHWMVRTNIKLDMCLNKVDRSLINQNTQEITILSQPLKTLDEQDQRQERYELMVEKLLIDYFTESYKSFLKLEDNYEPSMQELKLGFEKFVHIINTDIANLQTQNDNLYEKYQEVMKISQKIKTTREKWKALKSDSNKYENYVNAMKQKSQEWPGKLEKMKSECELKEEEIKALQSNISELHKILRKKGISTEQFELQNQEREKLTRELDKINIQSDKLTSSIKSRKLEAEGIFKSLLDTLRQYDSSIQNLTRSRSQLGHNVNDSSLKINISENLLDRDFHEGISYEQLFPKGSGINESIKKSILKLNDEIQERIKTIEKDNITLEKDIKNLKHDINEKTQINEKLELELSEANSKFELSKQENERLLVAQRIEIEKMEKKINDSNLLMKTKISDAEELVTSTELKLEELKVDLNRKRYKLHQQVIHVIDITSKFKINIQSSLENSENELGNVIEELRNLEFETEHNVTN", "length": 691 }, "evidence": [ { "id": "Q76I89", "url": "https://omabrowser.org/oma/group/Q76I89/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q6DRJ7-1", "protein_name": "Kinetochore protein NDC80 homolog", "gene_name": "ndc80", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSRRPSSRYSEMPMRVTDSRMSLINATPQNKDNAFGKLNIPKPQSTTSERRTSFFGKGIGAGGQRNSMFGSYGGSEKMKDPRALHDKAFVQQCIKQLYEFLVDRGFPGSITVKALQSPSTKEFLKIYEFIYNFLEPSFQMPTAKVEEEIPRMLKDLGYPFALSKSSMYSIGAPHTWPLALGALIWLMDAVKLFGGQREQDLLFSDFSDELCDLEDRTEYNKLIMEYCSDTYNKFMQGADTFDDEDDDFLYKLKKLYNVDEALLHSQQEKHSMLMEHVERLERESQTDRLVGKRTEKLRLQTDLQKLQNYRCTLEAHKTGLENKSAGLTEELEAVEMQLEGLKQERTRLQHILENQKFTPADIERINRERNELQQTIHGLSQSLEEGEQLVWNEEVNLSKTKEKAELKVAEYNKLGRKLKLIPLSAENACGHDFEIRADYSATTITQYKTQIQNPLKNMMVEVEEEFSRLSNVNLSLEETVEQVKSNIFDKENDIKQLKEQIRKVDQQLENAMQEMALEDDKWAAELDSAETHKKLFEKNVMQGIEEAEEEVKAAQQQYHVVVQETNEKNRMVVKNMTDLFSSTVNHLFAVEKHCDEQLKRFDKLKDIVREDEADINQLTDLVENFIKKANSL", "length": 632 }, "evidence": [ { "id": "Q76I89", "url": "https://omabrowser.org/oma/group/Q76I89/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q9D0F1-1", "protein_name": "Kinetochore protein NDC80 homolog", "gene_name": "Ndc80", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKRSSVSTCGAGRLSMQELRTLDLNKPGLYTPQTKERSTFGKLSTHKPTSERKVSIFGKRTSGHGSRNSQLGIFSSSEKIKDPRPLNDKAFIQQCIRQLYEFLTENGYVYSVSMKSLQAPSTKEFLKIFAFLYGFLCPSYELPGTKCEEEVPRIFKALGYPFTLSKSSMYTVGAPHTWPHIVAALVWLIDCIKIDTAMKESSPLFDDGQLWGEETEDGIKHNKLFLEYTKKCYEKFMTGADSFEEEDAELQAKLKDLYKVDASKLESLEAENKALNEQIARLEEEREREPNRLMSLKKLKASLQADVQNYKAYMSNLESHLAVLKQKSNSLDEEIGRVEQECETVKQENTRLQSIVDNQKYSVADIERINHEKNELQQTINKLTKDLEAEQQQMWNEELKYARGKEAIEAQLAEYHKLARKLKLIPKGAENSKGYDFEIKFNPEAGANCLVKYRTQVYAPLKELLNESEEEINKALNKKRHLEDTLEQLNTMKTESKNTVRMLKEEIQKLDDLHQQAVKEAEEKDKKSASELESLEKHKHLLESGVNDGLSEAMDELDAVQREYQLTVKTTTEERRKVENNLQRLLEMVATHVGSLEKHLEEENAKADREYEEFMSEDLLENIREMAEKYKRNAAQLKAPDK", "length": 642 }, "evidence": [ { "id": "Q76I89", "url": "https://omabrowser.org/oma/group/Q76I89/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9M1G5-1", "protein_name": "Kinetochore protein NDC80 homolog", "gene_name": "NDC80", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MRGGAAGKRRTTVGFGGAPPPPPPSIEQQRHLFNSRDSDASFASSRPSSIGLGGRGASDDRSSMIRFINAFLSTHNFPISIRGNPVPSVKDISETLKFLLSALDYPCDSIKWDEDLVFFLKSQKCPFKITKSSLKAPNTPHNWPTVLAVVHWLAELARFHQHLVSNSTSVPEDNSMNFFAIQSFGHFIRGEDDKVNDLDSQFLGKLEAEKTSVAETISGCEKISGELEAKLESLRKGPSKKESLEKVKADLENDVNKFRTIVVEYTDRNPAMEKVVEEKAKELKAKEEERERISVENKELKKSVELQNFSAADVNRMRRELQAVERDVADAEVARDGWDQKAWELNSQIRNQFHQIQTLAIDCNQALRRLKLDIQFAVNERGETPAAVMGVDYKSVVKPALCSLCDGIKGSSAEKVEELVTLQHHKSEMASKIESKRSLLGSIQLQINDLEEKMKLVKKETQELSTKCDLEAKTLVESVKAEALNLEVVEKEAAEFVKASELRLQEAVKESEEEVQACAAQLFALIDSISKQKEYMDSKISEIKTGVADTASAVSEIYKANFKKNLGI", "length": 568 }, "evidence": [ { "id": "Q76I89", "url": "https://omabrowser.org/oma/group/Q76I89/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 8, "go_terms": [ { "name": "metaphase chromosome alignment", "id": "GO:0051310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051310", "evidence": [ { "database": "UniProtKB", "id": "Q76I89", "url": "https://www.uniprot.org/uniprotkb/Q76I89" } ], "pmid": "" }, { "name": "attachment of mitotic spindle microtubules to kinetochore", "id": "GO:0051315", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051315", "evidence": [ { "database": "UniProtKB", "id": "Q76I89", "url": "https://www.uniprot.org/uniprotkb/Q76I89" } ], "pmid": "" }, { "name": "chromosome segregation", "id": "GO:0007059", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007059", "evidence": [ { "database": "UniProtKB", "id": "Q76I89", "url": "https://www.uniprot.org/uniprotkb/Q76I89" } ], "pmid": "" }, { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "Q76I89", "url": "https://www.uniprot.org/uniprotkb/Q76I89" } ], "pmid": "" }, { "name": "establishment of mitotic spindle orientation", "id": "GO:0000132", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000132", "evidence": [ { "database": "UniProtKB", "id": "Q76I89", "url": "https://www.uniprot.org/uniprotkb/Q76I89" } ], "pmid": "" }, { "name": "mitotic spindle organization", "id": "GO:0007052", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007052", "evidence": [ { "database": "UniProtKB", "id": "Q76I89", "url": "https://www.uniprot.org/uniprotkb/Q76I89" } ], "pmid": "" }, { "name": "positive regulation of mitotic cell cycle spindle assembly checkpoint", "id": "GO:0090267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090267", "evidence": [ { "database": "UniProtKB", "id": "Q76I89", "url": "https://www.uniprot.org/uniprotkb/Q76I89" } ], "pmid": "" }, { "name": "spindle organization", "id": "GO:0007051", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007051", "evidence": [ { "database": "UniProtKB", "id": "Q76I89", "url": "https://www.uniprot.org/uniprotkb/Q76I89" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "Ndc80 complex", "id": "GO:0031262", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031262", "evidence": [ { "database": "UniProtKB", "id": "Q76I89", "url": "https://www.uniprot.org/uniprotkb/Q76I89" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q76I89", "url": "https://www.uniprot.org/uniprotkb/Q76I89" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "Q76I89", "url": "https://www.uniprot.org/uniprotkb/Q76I89" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "Q76I89", "url": "https://www.uniprot.org/uniprotkb/Q76I89" } ], "pmid": "" }, { "name": "kinetochore", "id": "GO:0000776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000776", "evidence": [ { "database": "UniProtKB", "id": "Q76I89", "url": "https://www.uniprot.org/uniprotkb/Q76I89" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q76I89", "url": "https://www.uniprot.org/uniprotkb/Q76I89" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "Q76I89", "url": "https://www.uniprot.org/uniprotkb/Q76I89" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "Q76I89", "url": "https://www.uniprot.org/uniprotkb/Q76I89" } ], "pmid": "" }, { "name": "cyclin binding", "id": "GO:0030332", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030332", "evidence": [ { "database": "UniProtKB", "id": "Q76I89", "url": "https://www.uniprot.org/uniprotkb/Q76I89" } ], "pmid": "" }, { "name": "kinetochore adaptor activity", "id": "GO:0140483", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140483", "evidence": [ { "database": "UniProtKB", "id": "Q76I89", "url": "https://www.uniprot.org/uniprotkb/Q76I89" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 114, "end_pos": 116, "annotation": "n_glycosylation_sequon" }, { "start_pos": 469, "end_pos": 471, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q76I89-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 640, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q76I89-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q76I89" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 114, "end_pos": 116 }, { "start_pos": 469, "end_pos": 471 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": 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"length": 1304, "header": "tr|A0A8V0X804-1|A0A8V0X804_CHICK Isoform 1 of Hormone-sensitive lipase OS=Gallus gallus OX=9031 GN=LIPE PE=3 SV=1 CANONICAL=A0A8V0X804-1" }, "isoforms": [ { "isoform_ac": "A0A8V0X804-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X804/entry#A0A8V0X804-1", "sequence": { "sequence": 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"length": 1304, "header": "tr|A0A8V0X804-1|A0A8V0X804_CHICK Isoform 1 of Hormone-sensitive lipase OS=Gallus gallus OX=9031 GN=LIPE PE=3 SV=1 CANONICAL=A0A8V0X804-1" }, "locus": { "chromosome": "MU179273.1", "start_pos": 91248, "end_pos": 48878, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010001323.1", "url": "https://www.ensembl.org/id/ENSGALT00010001323.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010000694.1", "url": "https://www.ensembl.org/id/ENSGALP00010000694.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1275, "start_aa": "Thr", "end_pos": 1275, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1275", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "sterol ester esterase activity", "id": "GO:0004771", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004771", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0X804", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X804" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0X804", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X804" } ], "pmid": "" }, { "name": "monoacylglycerol lipase activity", "id": "GO:0047372", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047372", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0X804", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X804" } ], "pmid": "" }, { "name": "triacylglycerol lipase activity", "id": "GO:0004806", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004806", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0X804", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X804" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "lipid droplet", "id": "GO:0005811", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005811", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0X804", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X804" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0X804", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X804" } ], "pmid": "" }, { "name": "caveola", "id": "GO:0005901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005901", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0X804", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X804" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "cholesterol metabolic process", "id": "GO:0008203", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008203", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0X804", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X804" } ], "pmid": "" }, { "name": "triglyceride catabolic process", "id": "GO:0019433", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019433", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0X804", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X804" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "12044", "name": "", "equation": "a triacylglycerol + H2O = a diacylglycerol + a fatty acid + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZJ81-1", "A0A8V0ZWX8-1", "A0A8V0ZRC8-1", "A0A8V0X804-1", "A0A8V0Z5J2-1", "A0A8V0ZYA6-1", "P11602-1", "A0A1D5P986-1", "F1P1V6-1", "A0A8V0ZG82-1", "A0A8V1ALS7-1" ], "evidence": [ { "id": "12044", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/12044" } ] }, { "id": "13933", "name": "", "equation": "all-trans-retinyl hexadecanoate + H2O = all-trans-retinol + hexadecanoate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0X804-1" ], "evidence": [ { "id": "13933", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/13933" } ] }, { "id": "15245", "name": "", "equation": "a monoacylglycerol + H2O = glycerol + a fatty acid + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0X804-1" ], "evidence": [ { "id": "15245", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/15245" } ] }, { "id": "26132", "name": "", "equation": "2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerol + H2O = glycerol + (5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1C7F4-1", "A0A8V0X804-1", "Q5ZIN0-1", "A0A3Q2U9E5-1", "F1P1V6-1", "A0A8V0ZKJ9-1", "A0A8V1ACD9-1" ], "evidence": [ { "id": "26132", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/26132" } ] }, { "id": "32731", "name": "", "equation": "a diacylglycerol + H2O = a monoacylglycerol + a fatty acid + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0X804-1" ], "evidence": [ { "id": "32731", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/32731" } ] }, { "id": "33875", "name": "", "equation": "cholesteryl (9Z-octadecenoate) + H2O = cholesterol + (9Z)-octadecenoate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1NF25-1", "A0A8V0X804-1", "A0A8V1ALS7-1" ], "evidence": [ { "id": "33875", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/33875" } ] }, { "id": "38379", "name": "", "equation": "1,2-di-(9Z-octadecenoyl)-glycerol + (9Z)-octadecenoate + H(+) = 1,2,3-tri-(9Z-octadecenoyl)-glycerol + H2O", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0X804-1" ], "evidence": [ { "id": "38379", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/38379" } ] }, { "id": "38383", "name": "", "equation": "2,3-di-(9Z)-octadecenoyl-sn-glycerol + H2O = 2-(9Z-octadecenoyl)-glycerol + (9Z)-octadecenoate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0X804-1" ], "evidence": [ { "id": "38383", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/38383" } ] }, { "id": "38455", "name": "", "equation": "1,2-di-(9Z-octadecenoyl)-glycerol + H2O = (9Z-octadecenoyl)-glycerol + (9Z)-octadecenoate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0X804-1" ], "evidence": [ { "id": "38455", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/38455" } ] }, { "id": "38487", "name": "", "equation": "1-(9Z-octadecenoyl)-glycerol + H2O = glycerol + (9Z)-octadecenoate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0X804-1", "A0A8V0Z5J2-1", "Q5ZIN0-1", "A0A8V0ZJ81-1" ], "evidence": [ { "id": "38487", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/38487" } ] }, { "id": "38491", "name": "", "equation": "2-(9Z-octadecenoyl)-glycerol + H2O = glycerol + (9Z)-octadecenoate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0X804-1", "A0A8V0Z5J2-1", "Q5ZIN0-1" ], "evidence": [ { "id": "38491", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/38491" } ] }, { "id": "38563", "name": "", "equation": "1-O-hexadecyl-2-acetyl-sn-glycerol + H2O = 1-O-hexadecyl-sn-glycerol + acetate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1NF25-1", "A0A8V0X804-1" ], "evidence": [ { "id": "38563", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/38563" } ] }, { "id": "38575", "name": "", "equation": "1,2,3-tri-(9Z-octadecenoyl)-glycerol + H2O = di-(9Z)-octadecenoylglycerol + (9Z)-octadecenoate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZJ81-1", "A0A8V0X804-1", "A0A8V0Z5J2-1", "P11602-1", "A0A8V0ZYA6-1", "A0A1D5P986-1", "A0A8V1ALS7-1" ], "evidence": [ { "id": "38575", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/38575" } ] }, { "id": "38659", "name": "", "equation": "1,2-di-(9Z-octadecenoyl)-glycerol + H2O = 2-(9Z-octadecenoyl)-glycerol + (9Z)-octadecenoate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0X804-1" ], "evidence": [ { "id": "38659", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/38659" } ] }, { "id": "39935", "name": "", "equation": "1,2-di-(9Z-octadecenoyl)-sn-glycerol + H2O = (9Z-octadecenoyl)-glycerol + (9Z)-octadecenoate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0X804-1" ], "evidence": [ { "id": "39935", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/39935" } ] }, { "id": "39939", "name": "", "equation": "1,3-di-(9Z-octadecenoyl)-glycerol + H2O = 1-(9Z-octadecenoyl)-glycerol + (9Z)-octadecenoate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0X804-1", "A0A8V0Z5J2-1" ], "evidence": [ { "id": "39939", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/39939" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5P986", "gene_name": "LIPG", "activity": [ { "ec_number": "3.1.1.32", "activity": "a 1,2-diacyl-sn-glycero-3-phosphocholine + H2O = a 2-acyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "A0A1D5P986", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P986" } ] }, { "ec_number": "3.1.1.3", "activity": "a triacylglycerol + H2O = a diacylglycerol + a fatty acid + H(+).", "evidence": [ { "id": "A0A1D5P986", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P986" } ] }, { "ec_number": "3.1.1.3", "activity": "", "evidence": [ { "id": "A0A1D5P986", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P986" } ] }, { "ec_number": "3.1.1.32", 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"id": "PF07859", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07859" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Alpha/beta hydrolase fold-3", "eco_id": "ECO_0000259", "start_pos": 378, "end_pos": 526, "start_aa": "Leu", "end_aa": "Asp", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0X804", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X804" }, { "id": "PF06350", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06350" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Hormone-sensitive lipase N-terminal", "eco_id": "ECO_0000259", "start_pos": 217, "end_pos": 346, "start_aa": "Val", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.1.1.23", "ec_name": "Hydrolyzes glycerol monoesters of long-chain fatty acids.", "evidence": [ { "id": "3.1.1.23", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.1.1.23" } ] }, { "ec_number": "3.1.1.79", "ec_name": "a monoacylglycerol + H2O = glycerol + a fatty acid + H(+).", "evidence": [ { "id": "3.1.1.79", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.79" }, { "id": "3.1.1.79", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.1.1.79" } ] } ], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 1275 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 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"database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990115" } ] } ], "protein_names": [ { "name": "Protein Wnt-11", "type": "recommended", "evidence": [ { "id": "P49339", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P49339/entry#names_and_taxonomy" } ] }, { "name": "Wnt-11 protein", "type": "synonym", "evidence": [ { "id": "NP_990115", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990115" } ] }, { "name": "protein Wnt-11 precursor", "type": "synonym", "evidence": [ { "id": "NP_990115", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990115" } ] }, { "name": "protein Wnt-11", "type": "synonym", "evidence": [ { "id": "NP_990115", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990115" } ] }, { "name": "wingless-type MMTV integration site family, member 11", "type": "synonym", "evidence": [ { "id": "NP_990115", "database": "RefSeq", "url": 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The reference sequence was derived from D31901.1.", "evidence": [ { "database": "RefSeq", "id": "NP_990115", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990115" } ] }, { "annotation": "During early chick myogenesis WNT11 has an essential role in the oriented elongation of the myocytes", "evidence": [ { "database": "RefSeq", "id": "NP_990115", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990115" }, { "database": "PubMed", "id": "18987628", "url": "https://glygen.org/publication/PubMed/18987628" } ] }, { "annotation": "Ligand for members of the frizzled family of seven transmembrane receptors.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0X957", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X957#function" }, { "database": "UniProtKB", "id": "RU003500", "url": "https://www.uniprot.org/uniprotkb/RU003500#function" }, { "database": "UniProtKB", "id": "A0A8V0XFN1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFN1#function" } ] }, { "annotation": "Ligand for members of the frizzled family of seven transmembrane receptors. May play a role in the formation of dermal structure, both limb and feather buds. Is likely to signal over only few cell diameters.", "evidence": [ { "database": "UniProtKB", "id": "P49339", "url": "https://www.uniprot.org/uniprotkb/P49339#function" } ] }, { "annotation": "Wnt11 and Wnt6 act as factors maintaining the epithelial nature of the dorsomedial and ventrolateral lips of the dermomyotome, respectively, during dermomyotomal growth.", "evidence": [ { "database": "RefSeq", "id": "NP_990115", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990115" }, { "database": "PubMed", "id": "16818447", "url": "https://glygen.org/publication/PubMed/16818447" } ] }, { "annotation": "Wnt11 is required for dense dermis and subsequent cutaneous appendage formation, by influencing the cell fate decision of the cells in the dorsomedial lip. Erratum:[PLoS One. 2018 Sep 10;13(9):e0203913. doi: 10.1371/journal.pone.0203913. PMID: 30199548] Publication Status: Online-Only", "evidence": [ { "database": "RefSeq", "id": "NP_990115", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990115" }, { "database": "PubMed", "id": "24671096", "url": "https://glygen.org/publication/PubMed/24671096" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "P49339", "url": "https://www.uniprot.org/uniprotkb/P49339" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "WNT11", "url": "https://www.uniprot.org/uniprotkb/P49339", "locus": { "chromosome": "1", "start_pos": 193814683, "end_pos": 193749254, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010002356", "url": "https://www.ensembl.org/id/ENSGALG00010002356" } ] } } ], "crossref": [ { "id": "P49339", "url": "https://alphafold.ebi.ac.uk/entry/P49339", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000000839", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000000839", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd19343", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19343", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "395562", "url": "https://www.ncbi.nlm.nih.gov/gene/395562", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR005817", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005817", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018161", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018161", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043158", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043158", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:395562", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395562", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CKLLPGM", "url": "https://omabrowser.org/oma/group/CKLLPGM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0X957", "url": "https://www.orthodb.org/?gene=A0A8V0X957", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XFN1", "url": "https://www.orthodb.org/?gene=A0A8V0XFN1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "P49339", "url": "https://www.orthodb.org/?gene=P49339", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12027", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12027", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12027:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12027:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00110", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00110", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:P49339", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:P49339", "database": "PRO", "categories": [ "Protein" ] }, { "id": "R-GGA-3238698", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3238698", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-4086398", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4086398", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_990115", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990115", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0X957", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X957", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0X957-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X957-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XFN1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFN1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XFN1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFN1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P49339", "url": "https://www.uniprot.org/uniprotkb/P49339", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P49339-1", "url": "https://www.uniprot.org/uniprotkb/P49339-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKPSPQFFLAAFLSLILQTGICYGIKWIALSKTPSSLALNQTQHCKQLEGLVVSQVQLCRSNLELMQTIIQAAREVIKTCRKTFSDMRWNCSSIELAPNYLLDLERGTRESAFVYALSAAAISHTIARACTTGDLPGCSCGPIPGETPGPGYRWGGCADNLNYGLIMGSKFSDAPMKMKKSGSQANKLMHLHNSEVGRQVLKASLEMKCKCHGVSGSCSIKTCWKGLQELRDIALDLKNKYLSATKVVHRPMGTRKYLVPKDIDIRPVKETELIYLQSSPDFCMKNEKVGSHGTQDRQCNKTSNGSDSCDLMCCGRGYNPYMDKVVERCHCKYHWCCYVTCKKCERTVERYVCK", "length": 354, "header": "sp|P49339-1|WNT11_CHICK Isoform 1 of Protein Wnt-11 OS=Gallus gallus OX=9031 GN=WNT11 PE=2 SV=1 CANONICAL=P49339-1" }, "isoforms": [ { "isoform_ac": "A0A8V0X957-1", "url": "https://www.uniprot.org/uniprotkb/P49339/entry#A0A8V0X957-1", "sequence": { "sequence": "MKPSPQFFLAAFLSLILQTGICYGIKWIALSKTPSSLALNQTQHCKQLEGLVVSQVQLCRSNLELMQTIIQAAREVIKTCRKTFSDMRWNCSSIELAPNYLLDLERGTRESAFVYALSAAAISHTIARACTTGDLPGCSCGPIPDAPMKMKKSGSQANKLMHLHNSEVGRQVLKASLEMKCKCHGVSGSCSIKTCWKGLQELRDIALDLKNKYLSATKVVHRPMGTRKYLVPKDIDIRPVKETELIYLQSSPDFCMKNEKVGSHGTQDRQCNKTSNGSDSCDLMCCGRGYNPYMDKVVERCHCKYHWCCYVTCKKCERTVERYVCK", "length": 326, "header": "tr|A0A8V0X957-1|WNT11_CHICK Computationally mapped isoform of Protein Wnt-11 OS=Gallus gallus OX=9031 GN=WNT11 PE=2 SV=1 CANONICAL=P49339-1" }, "locus": { "chromosome": "1", "start_pos": 193778079, "end_pos": 193752694, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010005340.1", "url": "https://www.ensembl.org/id/ENSGALT00010005340.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010003179.1", "url": "https://www.ensembl.org/id/ENSGALP00010003179.1" } ] } }, { "isoform_ac": "A0A8V0XFN1-1", "url": "https://www.uniprot.org/uniprotkb/P49339/entry#A0A8V0XFN1-1", "sequence": { "sequence": "MKPSPQFFLAAFLSLILQTGICYGIKWIALSKTPSSLALNQTQHCKQLEGLVVSQVQLCRSNLELMQTIIQAAREVIKTCRKTFSDMRWNCSSIELAPNYLLDLERGTRESAFVYALSAAAISHTIARACTTGDLPGCSCGPIPGETPGPGYRWGGCADNLNYGLIMGSKFSDAPMKMKKSGSQANKLMHLHNSEVGRQVLKASLEMKCKCHGVSGSCSIKTCWKGLQELRDIALDLKNKYLSATKVVHRPMGTRKYLVPKDIDIRPVKETELIYLQSSPDFCMKNEKVGSHGTQDRWALKTGTSMSSGPQGDLEGHQKLQS", "length": 322, "header": "tr|A0A8V0XFN1-1|WNT11_CHICK Computationally mapped isoform of Protein Wnt-11 OS=Gallus gallus OX=9031 GN=WNT11 PE=2 SV=1 CANONICAL=P49339-1" }, "locus": { "chromosome": "1", "start_pos": 193811767, "end_pos": 193752694, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010005343.1", "url": "https://www.ensembl.org/id/ENSGALT00010005343.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010003182.1", "url": "https://www.ensembl.org/id/ENSGALP00010003182.1" } ] } }, { "isoform_ac": "P49339-1", "url": "https://www.uniprot.org/uniprotkb/P49339/entry#P49339-1", "sequence": { "sequence": "MKPSPQFFLAAFLSLILQTGICYGIKWIALSKTPSSLALNQTQHCKQLEGLVVSQVQLCRSNLELMQTIIQAAREVIKTCRKTFSDMRWNCSSIELAPNYLLDLERGTRESAFVYALSAAAISHTIARACTTGDLPGCSCGPIPGETPGPGYRWGGCADNLNYGLIMGSKFSDAPMKMKKSGSQANKLMHLHNSEVGRQVLKASLEMKCKCHGVSGSCSIKTCWKGLQELRDIALDLKNKYLSATKVVHRPMGTRKYLVPKDIDIRPVKETELIYLQSSPDFCMKNEKVGSHGTQDRQCNKTSNGSDSCDLMCCGRGYNPYMDKVVERCHCKYHWCCYVTCKKCERTVERYVCK", "length": 354, "header": "sp|P49339-1|WNT11_CHICK Isoform 1 of Protein Wnt-11 OS=Gallus gallus OX=9031 GN=WNT11 PE=2 SV=1 CANONICAL=P49339-1" }, "locus": { "chromosome": "1", "start_pos": 193778079, "end_pos": 193752694, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010005342.1", "url": "https://www.ensembl.org/id/ENSGALT00010005342.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010003181.1", "url": "https://www.ensembl.org/id/ENSGALP00010003181.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 300, "start_aa": "Asn", "end_pos": 300, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn300", "evidence": [ { "id": "P49339", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P49339#ptm_processing" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 304, "start_aa": "Asn", "end_pos": 304, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn304", "evidence": [ { "id": "P49339", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P49339#ptm_processing" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 40, "start_aa": "Asn", "end_pos": 40, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn40", "evidence": [ { "id": "P49339", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P49339#ptm_processing" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 90, "start_aa": "Asn", "end_pos": 90, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn90", "evidence": [ { "id": "P49339", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P49339#ptm_processing" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "Regulation of ectodermal Wnt6 expression by the neural tube is transduced by dermomyotomal Wnt11: a mechanism of dermomyotomal lip sustainment.", "journal": "Development (Cambridge, England)", "date": "2006-08", "authors": "Geetha-Loganathan Poongodi, Nimmagadda Suresh, Huang Ruijin, Christ Bodo, Scaal Martin", "evidence": [ { "database": "RefSeq", "id": "NP_990115", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990115" } ], "reference": [ { "type": "PubMed", "id": "16818447", "url": "https://glygen.org/publication/PubMed/16818447" } ] }, { "title": "WNT11 acts as a directional cue to organize the elongation of early muscle fibres.", "journal": "Nature", "date": "2009-01-29", "authors": "Gros J\u00e9r\u00f4me, Serralbo Olivier, Marcelle Christophe", "evidence": [ { "database": "RefSeq", "id": "NP_990115", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990115" } ], "reference": [ { "type": "PubMed", "id": "18987628", "url": "https://glygen.org/publication/PubMed/18987628" } ] }, { "title": "Wnt11 is required for oriented migration of dermogenic progenitor cells from the dorsomedial lip of the avian dermomyotome.", "journal": "PloS one", "date": "2014", "authors": "Morosan-Puopolo Gabriela, Balakrishnan-Renuka Ajeesh, Yusuf Faisal, Chen Jingchen, Dai Fangping, Zoidl Georg, L\u00fcdtke Timo H-W, Kispert Andreas, Theiss Carsten, Abdelsabour-Khalaf Mohammed, Brand-Saberi Beate", "evidence": [ { "database": "RefSeq", "id": "NP_990115", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990115" } ], "reference": [ { "type": "PubMed", "id": "24671096", "url": "https://glygen.org/publication/PubMed/24671096" } ] }, { "title": "Cloning and characterization of Wnt-4 and Wnt-11 cDNAs from chick embryo.", "journal": "DNA Seq.", "date": "1995", "authors": "Tanda N, Kawakami Y, Saito T, Noji S, Nohno T", "evidence": [ { "database": "UniProtKB", "id": "P49339", "url": "https://www.uniprot.org/uniprotkb/P49339" } ], "reference": [ { "type": "PubMed", "id": "7579581", "url": "https://glygen.org/publication/PubMed/7579581" } ] }, { "title": "A chicken Wnt gene, Wnt-11, is involved in dermal development.", "journal": "Biochem. Biophys. Res. Commun.", "date": "1995", "authors": "Tanda N, Ohuchi H, Yoshioka H, Noji S, Nohno T", "evidence": [ { "database": "UniProtKB", "id": "P49339", "url": "https://www.uniprot.org/uniprotkb/P49339" } ], "reference": [ { "type": "PubMed", "id": "7779076", "url": "https://glygen.org/publication/PubMed/7779076" } ] } ], "pathway": [ { "id": "gga:395562", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395562", "resource": "KEGG Pathway" }, { "id": "R-GGA-3238698", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3238698", "resource": "Reactome", "description": "WNT ligand biogenesis and trafficking" }, { "id": "R-GGA-4086398", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4086398", "resource": "Reactome", "description": "Ca2+ pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1N4C0-1", "protein_name": "Protein Wnt", "gene_name": "WNT11", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": 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"evidence": [ { "database": "UniProtKB", "id": "P49339", "url": "https://www.uniprot.org/uniprotkb/P49339" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P49339", "url": "https://www.uniprot.org/uniprotkb/P49339" } ], "pmid": "" }, { "name": "extracellular matrix", "id": "GO:0031012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031012", "evidence": [ { "database": "UniProtKB", "id": "P49339", "url": "https://www.uniprot.org/uniprotkb/P49339" } ], "pmid": "" }, { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "P49339", "url": "https://www.uniprot.org/uniprotkb/P49339" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 31, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "P49339", "url": "https://www.uniprot.org/uniprotkb/P49339" } ], "pmid": "" }, { "name": "negative regulation of cell population proliferation", "id": "GO:0008285", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008285", "evidence": [ { "database": "UniProtKB", "id": "P49339", "url": "https://www.uniprot.org/uniprotkb/P49339" } ], "pmid": "" }, { "name": "positive regulation of gene expression", "id": "GO:0010628", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010628", "evidence": [ { "database": "UniProtKB", "id": "P49339", "url": "https://www.uniprot.org/uniprotkb/P49339" } ], "pmid": "" }, { "name": "negative regulation of gene expression", "id": "GO:0010629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010629", "evidence": [ { "database": "UniProtKB", "id": "P49339", "url": "https://www.uniprot.org/uniprotkb/P49339" } ], "pmid": "" }, { "name": "cell migration", "id": "GO:0016477", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016477", "evidence": [ { "database": "UniProtKB", "id": "P49339", "url": "https://www.uniprot.org/uniprotkb/P49339" } ], "pmid": "" }, { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "P49339", "url": "https://www.uniprot.org/uniprotkb/P49339" } ], "pmid": "" }, { "name": "negative regulation of canonical Wnt signaling pathway", "id": "GO:0090090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090090", "evidence": [ { "database": "UniProtKB", "id": "P49339", "url": "https://www.uniprot.org/uniprotkb/P49339" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "P49339", "url": "https://www.uniprot.org/uniprotkb/P49339" } ], "pmid": "" }, { "name": "neuron differentiation", "id": "GO:0030182", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030182", "evidence": [ { "database": "UniProtKB", "id": "P49339", "url": "https://www.uniprot.org/uniprotkb/P49339" } ], "pmid": "" }, { "name": "ventricular septum development", "id": "GO:0003281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003281", "evidence": [ { "database": "UniProtKB", "id": "P49339", "url": "https://www.uniprot.org/uniprotkb/P49339" } ], "pmid": "" }, { "name": "canonical Wnt signaling pathway", "id": "GO:0060070", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060070", "evidence": [ { "database": "UniProtKB", "id": "P49339", "url": "https://www.uniprot.org/uniprotkb/P49339" } ], "pmid": "" }, { "name": "Wnt signaling pathway, planar cell polarity pathway", "id": "GO:0060071", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060071", "evidence": [ { "database": "UniProtKB", "id": "P49339", "url": "https://www.uniprot.org/uniprotkb/P49339" } ], "pmid": "" }, { "name": "face morphogenesis", "id": "GO:0060325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060325", "evidence": [ { "database": "UniProtKB", "id": "P49339", "url": "https://www.uniprot.org/uniprotkb/P49339" } ], "pmid": "" }, { "name": "epithelial to mesenchymal transition", "id": "GO:0001837", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001837", "evidence": [ { "database": "UniProtKB", "id": "P49339", "url": "https://www.uniprot.org/uniprotkb/P49339" } ], "pmid": "" }, { "name": "adrenal gland development", "id": "GO:0030325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030325", "evidence": [ { "database": "UniProtKB", "id": "P49339", "url": "https://www.uniprot.org/uniprotkb/P49339" } ], "pmid": "" }, { "name": "atrial septum development", "id": "GO:0003283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003283", "evidence": [ { "database": "UniProtKB", "id": "P49339", "url": "https://www.uniprot.org/uniprotkb/P49339" } ], "pmid": "" }, { "name": "myoblast differentiation", "id": "GO:0045445", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045445", "evidence": [ { "database": "UniProtKB", "id": "P49339", "url": "https://www.uniprot.org/uniprotkb/P49339" } ], "pmid": "" }, { "name": "skin morphogenesis", "id": "GO:0043589", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043589", "evidence": [ { "database": "UniProtKB", "id": "P49339", "url": "https://www.uniprot.org/uniprotkb/P49339" } ], "pmid": "" }, { "name": "secondary heart field specification", "id": "GO:0003139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003139", "evidence": [ { "database": "UniProtKB", "id": "P49339", "url": "https://www.uniprot.org/uniprotkb/P49339" } ], "pmid": "" }, { "name": "neuroendocrine cell differentiation", "id": "GO:0061101", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061101", "evidence": [ { "database": "UniProtKB", "id": "P49339", "url": "https://www.uniprot.org/uniprotkb/P49339" } ], "pmid": "" }, { "name": "embryonic viscerocranium morphogenesis", "id": "GO:0048703", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048703", "evidence": [ { "database": "UniProtKB", "id": "P49339", "url": "https://www.uniprot.org/uniprotkb/P49339" } ], "pmid": "" }, { "name": "cell fate commitment", "id": "GO:0045165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045165", "evidence": [ { "database": "UniProtKB", "id": "P49339", "url": "https://www.uniprot.org/uniprotkb/P49339" } ], "pmid": "" }, { "name": "cloacal septation", "id": "GO:0060197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060197", "evidence": [ { "database": "UniProtKB", "id": "P49339", "url": "https://www.uniprot.org/uniprotkb/P49339" } ], "pmid": "" }, { "name": "lung-associated mesenchyme development", "id": "GO:0060484", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060484", "evidence": [ { "database": "UniProtKB", "id": "P49339", "url": "https://www.uniprot.org/uniprotkb/P49339" } ], "pmid": "" }, { "name": "mesonephric duct development", "id": "GO:0072177", "url": 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"https://www.uniprot.org/uniprotkb/Q5ZMF3/entry#names_and_taxonomy" } ] }, { "name": "2.7.1.74", "type": "synonym", "evidence": [ { "id": "Q5ZMF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZMF3/entry#names_and_taxonomy" } ] }, { "name": "2.7.1.76", "type": "synonym", "evidence": [ { "id": "Q5ZMF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZMF3/entry#names_and_taxonomy" } ] }, { "name": "Deoxyadenosine kinase", "type": "synonym", "evidence": [ { "id": "Q5ZMF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZMF3/entry#names_and_taxonomy" } ] }, { "name": "Deoxyguanosine kinase", "type": "synonym", "evidence": [ { "id": "Q5ZMF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZMF3/entry#names_and_taxonomy" } ] }, { "name": "GgdCK", "type": "synonym", "evidence": [ { "id": "Q5ZMF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZMF3/entry#names_and_taxonomy" } ] }, { "name": "deoxyadenosine kinase", "type": "synonym", "evidence": [ { "id": "NP_001006451", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006451" } ] }, { "name": "deoxycytidine kinase", "type": "synonym", "evidence": [ { "id": "NP_001006451", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006451" } ] }, { "name": "deoxyguanosine kinase", "type": "synonym", "evidence": [ { "id": "NP_001006451", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006451" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ719431.1, HAEK01059701.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000074.1. On Nov 22, 2004 this sequence version replaced XP_420602.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001006451", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006451" } ] }, { "annotation": "Phosphorylates the deoxyribonucleosides deoxycytidine, deoxyguanosine and deoxyadenosine (PubMed:27906638). Displays highest activity against deoxycytidine followed by deoxyadenosine and then deoxyguanosine (PubMed:27906638). Shows only very minor activity against deoxyuridine and deoxythymidine (PubMed:27906638).", "evidence": [ { "database": "UniProtKB", "id": "Q5ZMF3", "url": "https://www.uniprot.org/uniprotkb/Q5ZMF3#function" }, { "database": "PubMed", "id": "27906638", "url": "https://glygen.org/publication/PubMed/27906638" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZMF3", "url": "https://www.uniprot.org/uniprotkb/Q5ZMF3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "DCK", "url": "https://www.uniprot.org/uniprotkb/Q5ZMF3", "locus": { "chromosome": "4", "start_pos": 49647426, "end_pos": 49635551, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010004283", "url": "https://www.ensembl.org/id/ENSGALG00010004283" } ] } } ], "crossref": [ { "id": "Q5ZMF3", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZMF3", "database": "AlphaFoldDB", "categories": [] }, { "id": "2.7.1.74", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.7.1.74&UniProtAcc=Q5ZMF3", "database": "BRENDA", "categories": [ "Enzyme and Pathway" ] }, { "id": "cd01673", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01673", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "422648", "url": "https://www.ncbi.nlm.nih.gov/gene/422648", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002624", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002624", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031314", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031314", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050566", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050566", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:422648", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422648", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "EAMVMTP", "url": "https://omabrowser.org/oma/group/EAMVMTP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XCJ3", "url": "https://www.orthodb.org/?gene=A0A8V0XCJ3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "Q5ZMF3", "url": "https://www.orthodb.org/?gene=Q5ZMF3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10513", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10513", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10513:SF19", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10513:SF19", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01712", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01712", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5ZMF3", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5ZMF3", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001006451", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006451", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "19201", "url": "https://www.rhea-db.org/rhea/19201", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "20061", "url": "https://www.rhea-db.org/rhea/20061", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "23452", "url": "https://www.rhea-db.org/rhea/23452", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0XCJ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCJ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XCJ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCJ3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZMF3", "url": "https://www.uniprot.org/uniprotkb/Q5ZMF3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZMF3-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZMF3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MATPPKRGRLEGRVKKIAVEGNIAAGKSTFVNILKQADEGWEVVPEPVARWCNVQQNSEEDCEELTTSQKSGGNVLQMMYEKPERWSFTFQMYACLSRIRAQLKSIDGKLREAENPVVFFERSVYSDRYIFAANLYESDCMNETEWTIYQDWHDWMNKQFGQSLALDGIIYLRATPEKCLNRIYLRGRDEEQEIPIEYLEKLHYKHESWLQHKTLRTDFEYLQEIPILTLDVNEDFKGKKDRYDHMTEKVKEFLSTL", "length": 257, "header": "sp|Q5ZMF3-1|DCK_CHICK Isoform 1 of Deoxycytidine kinase OS=Gallus gallus OX=9031 GN=DCK PE=1 SV=1 CANONICAL=Q5ZMF3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0XCJ3-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZMF3/entry#A0A8V0XCJ3-1", "sequence": { "sequence": "MATPPKRGRLEGRVKKIAVEGNIAAGKSTFVNILKQADEGWEVVPEPVARWCNVQQNSEEDCEELTTSQKSGGNVLQMMYEKPERWSFTFQMYACLSRIRAQLKSIDGKLREAENPVVFFERSVYSDRYIFAANLYESDCMNETEWTIYQDWHDWMNKQFGQSLALDGIIYLRATPEKCLNRIYLRGRDEEQEIPIEYLEKLHYKHESWLQHKTLRTDFEYLQEIPILTLDVNEDFKGKKDRYDHMTEKVKSDETTYISTLIANLSK", "length": 267, "header": "tr|A0A8V0XCJ3-1|DCK_CHICK Computationally mapped isoform of Deoxycytidine kinase OS=Gallus gallus OX=9031 GN=DCK PE=1 SV=1 CANONICAL=Q5ZMF3-1" }, "locus": { "chromosome": "4", "start_pos": 49642663, "end_pos": 49635657, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010010010.1", "url": "https://www.ensembl.org/id/ENSGALT00010010010.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010005853.1", "url": "https://www.ensembl.org/id/ENSGALP00010005853.1" } ] } }, { "isoform_ac": "Q5ZMF3-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZMF3/entry#Q5ZMF3-1", "sequence": { "sequence": "MATPPKRGRLEGRVKKIAVEGNIAAGKSTFVNILKQADEGWEVVPEPVARWCNVQQNSEEDCEELTTSQKSGGNVLQMMYEKPERWSFTFQMYACLSRIRAQLKSIDGKLREAENPVVFFERSVYSDRYIFAANLYESDCMNETEWTIYQDWHDWMNKQFGQSLALDGIIYLRATPEKCLNRIYLRGRDEEQEIPIEYLEKLHYKHESWLQHKTLRTDFEYLQEIPILTLDVNEDFKGKKDRYDHMTEKVKEFLSTL", "length": 257, "header": "sp|Q5ZMF3-1|DCK_CHICK Isoform 1 of Deoxycytidine kinase OS=Gallus gallus OX=9031 GN=DCK PE=1 SV=1 CANONICAL=Q5ZMF3-1" }, "locus": { "chromosome": "4", "start_pos": 49644752, "end_pos": 49635657, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010010013.1", "url": "https://www.ensembl.org/id/ENSGALT00010010013.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010005854.1", "url": "https://www.ensembl.org/id/ENSGALP00010005854.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5ZMF3", "url": "https://www.uniprot.org/uniprotkb/Q5ZMF3" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] }, { "title": "Gene duplications and losses among vertebrate deoxyribonucleoside kinases of the non-TK1 Family.", "journal": "Nucleosides, nucleotides & nucleic acids", "date": "2016-12", "authors": "Mutahir Zeeshan, Christiansen Louise Slot, Clausen Anders R, Berchtold Martin W, Gojkovic Zoran, Munch-Petersen Birgitte, Knecht Wolfgang, Pi\u0161kur Jure", "evidence": [ { "database": "UniProtKB", "id": "Q5ZMF3", "url": "https://www.uniprot.org/uniprotkb/Q5ZMF3" } ], "reference": [ { "type": "PubMed", "id": "27906638", "url": "https://glygen.org/publication/PubMed/27906638" } ] } ], "pathway": [ { "id": "gga:422648", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422648", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "G3I4C0-1", "protein_name": "Deoxycytidine kinase", "gene_name": "Dck", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MATPPKRFCPSPSTSSEGTRIKKISIEGNIAAGKSTFVNILKQVCEDWEVVPEPVARWCNVQNTQDEFEELTTSQKSGGNVLQMMYQKPERWSFTFQSYACLSRIRAQLASLNGKLKDAEKPVLFFERSVYSDRYIFASNLYESDCMNETEWTIYQDWHDWMNSQFGQSLELDGIIYLRATPEKCLNRIYLRGRDEEQGIPLEYLEKLHYKHESWLLHRTLKTNFDYLQEVPILTLDVNEDFKDKHESLVEKVKEFLSTL", "length": 260 }, "evidence": [ { "id": "Q5ZMF3", "url": "https://omabrowser.org/oma/group/Q5ZMF3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P27707-1", "protein_name": "Deoxycytidine kinase", "gene_name": "DCK", "tax_id": 9606, 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Maybe involved in the in 45S precursor rRNA production (By similarity).", "evidence": [ { "database": "UniProtKB", "id": "Q06A37", "url": "https://www.uniprot.org/uniprotkb/Q06A37#function" }, { "database": "UniProtKB", "id": "Q9P2D1", "url": "https://www.uniprot.org/uniprotkb/Q9P2D1#function" } ] }, { "annotation": "CChd7 was expressed in the neural epithelium, the otic placodes, the optic placodes, the branchial arches, and the olfactory placodes, which are the primordial tissues that give rise to organs affected in human CHARGE syndrome patients.", "evidence": [ { "database": "RefSeq", "id": "NP_001071054", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001071054" }, { "database": "PubMed", "id": "17149726", "url": "https://glygen.org/publication/PubMed/17149726" } ] }, { "annotation": "Let-7 miRNAs inhibit CHD7 expression and control auditory-sensory progenitor cell behavior in the developing inner ear. Publication Status: Online-Only", "evidence": [ { "database": "RefSeq", "id": "NP_001071054", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001071054" }, { "database": "PubMed", "id": "32816902", "url": "https://glygen.org/publication/PubMed/32816902" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q06A37", "url": "https://www.uniprot.org/uniprotkb/Q06A37" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CHD7", "url": "https://www.uniprot.org/uniprotkb/Q06A37", "locus": { "chromosome": "2", "start_pos": 112706445, "end_pos": 112581918, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010002626", "url": "https://www.ensembl.org/id/ENSGALG00010002626" } ] } } ], "crossref": [ { "id": "cd18059", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18059", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18663", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18663", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18668", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18668", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18793", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18793", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "421140", "url": "https://www.ncbi.nlm.nih.gov/gene/421140", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000330", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000330", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000953", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000953", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001650", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001650", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006576", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006576", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014001", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014001", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016197", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016197", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023780", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023780", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037259", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037259", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038718", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038718", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049730", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049730", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051493", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051493", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056342", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056342", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:421140", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421140", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "AFVAMCK", "url": "https://omabrowser.org/oma/group/AFVAMCK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q06A37", "url": "https://www.orthodb.org/?gene=Q06A37", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46850", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46850", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46850:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46850:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00176", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00176", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00271", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00271", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00385", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00385", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07533", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07533", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23078", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23078", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q06A37", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q06A37", "database": "PRO", "categories": [ "Protein" ] }, { "id": "R-GGA-9943962", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9943962", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001071054", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001071054", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "13065", "url": "https://www.rhea-db.org/rhea/13065", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0XDW9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XDW9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XDW9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XDW9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q06A37", "url": "https://www.uniprot.org/uniprotkb/Q06A37", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q06A37-1", "url": "https://www.uniprot.org/uniprotkb/Q06A37-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MADPGMMSLFGEDGNIFSEGLEGLGECGYPENTVNPMGQQMPMDQGFPSLQSSLHHPPANQNQAKLTHFDHYNQYEQQKMHLMDQPNRMISNAPGNGIASPHSQYHNPPVPQVPHGSGASGQMGVYPSMQNERHGQPFVDSGSMWGPRAVQVPDQIRAPYQQQQQQPQPTQPPQAPSGPPGQGHPQHMQQMGNYMARGDFSMQQHGQPQQQRMNQFSQGQEGLNQGNPFIATSGPGHLSHVPQQNPSMAPSLRHSVQQFHHHPPTALHGESVAHSPRFSPNPPQQGAVRPQTLNFSSRSQTVPSPTINNSGQYSRYPYSNLNQGLVNNTGMNQNLGLTNNTPMNQSVPRYPNAVGFPSNSGQGLMHQQPIHPSGSLNQMNTQTMHPSQPQGTYASPPPMSPMKAMSNPAGTPPPQVRPGSAGIPMEVGSYPNIPHPQPSHQPPGAMGIGQRNMGPRNMQQNRPFMGMSSTPREMGGHMRPNGCPGVGLADPQAIQERLISGQQLPSQQQSFQQQMPTCPPMQPHPGIHHQSSPPPHPHHQPWAQLHQSPQNTPQKVPVLQHSPSEPFLEKPVPDMTQVSGPNTQLVKSDDYLPSVEPQPQQKKKKKKNNHIAAEGPSKSFGKEDFPGGLDSQNLSRNSVDCSQEDKKKKKKPKAKKEPKDPKEPKEKKEPKTPKVPKTPKEPKEKKAKNTTPKPKTSKKTSNKKTDSESSAAKKKVNKGKEGSENSDLDKTPPPSPHPEDEDDPGVQKRRSSRQVKRKRYTEDLEFKISDEEADDADAAGRDSPSNTSQSEQQESADAEGPVVEKIMSSRSVKKKMENGEEVEIEEFYVKYKNFSYLHCQWASVEELDKDKRIQQKIKRFKAKQGQNKFLSEIDDELFNPDYVEIDRILDFSRSTDDNGEPVTHYLVKWCSLPYEDSTWELKQDIDQAKIEEFEKLMSREPEMERVERPPADDWKKSESSREYKNNNKLREYQLEGVNWLLFNWYNTRNCILADEMGLGKTIQSITFLYEIYLKGIHGPFLVIAPLSTIPNWEREFRTWTELNVVVYHGSQASRRTIQLYEMYFKDPQGRVIKGSYKFHAIITTFEMILTDCPELRNIPWRCVVIDEAHRLKNRNCKLLEGLKMMDLEHKVLLTGTPLQNTVEELFSLLHFLEPGRFPSETTFMQEFGDLKTEEQVQKLQAILKPMMLRRLKEDVEKNLAPKEETIIEVELTNIQKKYYRAILEKNFAFLSKGGGQANVPNLLNTMMELRKCCNHPYLINGAEEKILEEFKETHNADSPDFQLQAMIQAAGKLVLIDKLLPKLKAGGHRVLIFSQMVRCLDILEDYLIQRRYPYERIDGRVRGNLRQAAIDRFSRPDSDRFVFLLCTRAGGLGINLTAADTCIIFDSDWNPQNDLQAQARCHRIGQSKSVKIYRLITRNSYEREMFDKASLKLGLDKAVLQSMSGRENATNGVQQLSKKEIEDLLRKGAYGALMDEEDEGSKFCEEDIDQILLRRTHTITIESEGKGSTFAKASFVASGNRTDISLDDPNFWQKWAKKAELDIDALNGRNNLVIDTPRVRKQTRLYSAVKEDELMEFSDLESDSEEKPSTKPRRPQDKSQGYARSECFRVEKNLLVYGWGRWTDILSHGRYKRQLTEQDVETICRTILVYCLNHYKGDENIKSFIWDLITPTADGQTRALVNHSGLSAPVPRGRKGKKVKAQSSQPMLQDADWLTTCNPDVLFQEDSYRKHLKHHCNKVLLRVRMLYYLRQEVIGDQADRILEGADSSEVDVWIPEPFHAEVPADWWDKEADKSLLIGVFKHGYEKYNSMRADSTLCFLERVGMPDAKAIAAEQRGTDMLADGGDGGEFDREDEDPEYKPTRTPFKDEIDEFANSPPEDKEESIEIHPNKHSESNSELGQLYWPNTSTLTTRLRRLITAYQRSYKRQQMRQEALMKTDRRRRRPREEVRALEAEREAIITEKRQKWTRREEADFYRVVSTFGIIFDPIKHQFDWNQFRAFARLDKKSDESLEKYFNGFVNMCRRVCRMPVKPDDEPPDLSTMIEPITEERASRTLYRIELLRKIREQVLHHPQLGERLKLCQPSLDLPEWWECGKHDKDLLIGAAKHGVSRTDYHILNDPELSFLEAHKNFAQNRGTGNANTVSSLHPVGAGCSQTPPIVPSTPVQEEKSTEQTESKVEGSENPAAKEKSDIKEETDIADKDTKQDCDAEAETGSVKCELKDIEMSTDVDPKSISEKGSEEDEEEKLDDDDKSEESSQPEAGAVSQGKNFDEESNASMSTARDETRDGFYMEDGDPSVVQLLHERTFAFSFWPKDRVMINRLDNICEAVLKGKWPVNRRQMFDFQGLIPGYTPTAVDSPLQKRSFAELSMIGQASISGSEDITASPQLSKEDALNLSVPRQRRRRRRKIEIEAERAAKRRNLMEMVAQLRESQVVSENGQEKVVDLSKASREATSSTSNFSSVTSKFILPNVSTPVSDAFKTQMELLQAGLSRTPTRHLLNGSLIDGEPPMKRRRGRRKNVEGLDLLFMSNKRTSLTVEDAEVTKAFEEDMEALPARNIPSPGQLDPDTRIPVINLEDGTRLVGEDAPKNKDLVEWLKLHPTYTVDMPSYVPKSADVLFSSFQKPKQKRHRCRNPNKLDINTLTGEERVPVVNKRNGKKMGGAMAPPMKDLPRWLEENPEFAVAPDWTDIVKQSGFVPESMFDRLLTGPVVREEGASRRGRRPKSEIAKAAAAAAAVASTSGINPLLMNSLFAGMDLTSLQNLQNLQSLQLAGLMGFPPGLATAAAAGGDAKNPAAMLPLMLPGMAGLPNMFGLSGLLNNPITATTGNATTASGQGETEDGASKAEEKKNENEEENKDSEKSTDTVSATDSANGSVSAATAATTATATTTTTTNTGLPTNPLAFNPFLLSTMAPGLFYPSMFLPPGLGGLTLPGFPALAGLQNAVGSNEEKATDKTEGTAFKDEENLEGSDAEESLDKTADSSILEDEIAQGEELDSLDGGEEIENNENDE", "length": 3011, "header": "sp|Q06A37-1|CHD7_CHICK Isoform 1 of ATP-dependent chromatin remodeler CHD7 OS=Gallus gallus OX=9031 GN=CHD7 PE=2 SV=1 CANONICAL=Q06A37-1" }, "isoforms": [ { "isoform_ac": "A0A8V0XDW9-1", "url": "https://www.uniprot.org/uniprotkb/Q06A37/entry#A0A8V0XDW9-1", "sequence": { "sequence": "MADPGMMSLFGEDGNIFSEGLEGLGECGYPENTVNPMGQQMPMDQGFPSLQSSLHHPPANQNQAKLTHFDHYNQYEQQKMHLMDQPNRMISNAPGNGIASPHSQYHNPPVPQVPHGSGASGQMGVYPSMQNERHGQPFVDSGSMWGPRAVQVPDQIRAPYQQQQQQPQPTQPPQAPSGPPGQGHPQHMQQMGNYMARGDFSMQQHGQPQQQRMNQFSQGQEGLNQGNPFIATSGPGHLSHVPQQNPSMAPSLRHSVQQFHHHPPTALHGESVAHSPRFSPNPPQQGAVRPQTLNFSSRSQTVPSPTINNSGQYSRYPYSNLNQGLVNNTGMNQNLGLTNNTPMNQSVPRYPNAVGFPSNSGQGLMHQQPIHPSGSLNQMNTQTMHPSQPQGTYASPPPMSPMKAMSNPAGTPPPQVRPGSAGIPMEVGSYPNIPHPQPSHQPPGAMGIGQRNMGPRNMQQNRPFMGMSSTPREMGGHMRPNGCPGVGLADPQAIQERLISGQQLPSQQQSFQQQMPTCPPMQPHPGIHHQSSPPPHPHHQPWAQLHQSPQNTPQKVPVLQHSPSEPFLEKPVPDMTQVSGPNTQLVKSDDYLPSVEPQPQQKKKKKKNNHIAAEGPSKSFGKEDFPGGLDSQNLSRNSVDCSQEDKKKKKKPKAKKEPKDPKEPKEKKEPKTPKVPKTPKEPKEKKAKNTTPKPKTSKKTSNKKTDSESSAAKKKVNKGKEGSENSDLDKTPPPSPHPEDEDDPGVQKRRSSRQVKRKRYTEDLEFKISDEEADDADAAGRDSPSNTSQSEQQVRFEWSGKVDATAKFKVQIWAFFLNDINPCSYLHCQWASVEELDKDKRIQQKIKRFKAKQGQNKFLSEIDDELFNPDYVEIDRILDFSRSTDDNGEPVTHYLVKWCSLPYEDSTWELKQDIDQAKIEEFEKLMSREPEMERVERPPADDWKKSESSREYKNNNKLREYQLEGVNWLLFNWYNTRNCILADEMGLGKTIQSITFLYEIYLKGIHGPFLVIAPLSTIPNWEREFRTWTELNVVVYHGSQASRRTIQLYEMYFKDPQGRVIKGSYKFHAIITTFEMILTDCPELRNIPWRCVVIDEAHRLKNRNCKLLEGLKMMDLEHKVLLTGTPLQNTVEELFSLLHFLEPGRFPSETTFMQEFGDLKTEEQVQKLQAILKPMMLRRLKEDVEKNLAPKEETIIEVELTNIQKKYYRAILEKNFAFLSKGGGQANVPNLLNTMMELRKCCNHPYLINGAEEKILEEFKETHNADSPDFQLQAMIQAAGKLVLIDKLLPKLKAGGHRVLIFSQMVRCLDILEDYLIQRRYPYERIDGRVRGNLRQAAIDRFSRPDSDRFVFLLCTRAGGLGINLTAADTCIIFDSDWNPQNDLQAQARCHRIGQSKSVKIYRLITRNSYEREMFDKASLKLGLDKAVLQSMSGRENATNGVQQLSKKEIEDLLRKGAYGALMDEEDEGSKFCEEDIDQILLRRTHTITIESEGKGSTFAKASFVASGNRTDISLDDPNFWQKWAKKAELDIDALNGRNNLVIDTPRVRKQTRLYSAVKEDELMEFSDLESDSEEKPSTKPRRPQDKSQGYARSECFRVEKNLLVYGWGRWTDILSHGRYKRQLTEQDVETICRTILVYCLNHYKGDENIKSFIWDLITPTADGQTRALVNHSGLSAPVPRGRKGKKVKAQSSQPMLQDADWLTTCNPDVLFQEDSYRKHLKHHCNKVLLRVRMLYYLRQEVIGDQADRILEGADSSEVDVWIPEPFHAEVPADWWDKEADKSLLIGVFKHGYEKYNSMRADSTLCFLERVGMPDAKAIAAEQRGTDMLADGGDGGEFDREDEDPEYKPTRTPFKDEIDEFANSPPEDKEESIEIHPNKHSESNSELGQLYWPNTSTLTTRLRRLITAYQRSYKRQQMRQEALMKTDRRRRRPREEVRALEAEREAIITEKRQKWTRREEADFYRVVSTFGIIFDPIKHQFDWNQFRAFARLDKKSDESLEKYFNGFVNMCRRVCRMPVKPDDEPPDLSTMIEPITEERASRTLYRIELLRKIREQVLHHPQLGERLKLCQPSLDLPEWWECGKHDKDLLIGAAKHGVSRTDYHILNDPELSFLEAHKNFAQNRGTGNANTVSSLHPVGAGCSQTPPIVPSTPVQEEKSTEQTESKVEGSENPAAKEKSDIKEETDIADKDTKQDCDAEAETGSVKCELKDIEMSTDVDPKSISEKGSEEDEEEKLDDDDKSEESSQPEAGAVSQGKNFDEESNASMSTARDETRDGFYMEDGDPSVVQLLHERTFAFSFWPKDRVMINRLDNICEAVLKGKWPVNRRQMFDFQGLIPGYTPTAVDSPLQKRSFAELSMIGQASISGSEDITASPQLSKEDALNLSVPRQRRRRRRKIEIEAERAAKRRNLMEMVAQLRESQVVSENGQEKVVDLSKASREATSSTSNFSSVTSKFILPNVSTPVSDAFKTQMELLQAGLSRTPTRHLLNGSLIDGEPPMKRRRGRRKNVEGLDLLFMSNKRTSLTVEDAEVTKAFEEDMEALPARNIPSPGQLDPDTRIPVINLEDGTRLVGEDAPKNKDLVEWLKLHPTYTVDMPSYVPKSADVLFSSFQKPKQKRHRCRNPNKLDINTLTGEERVPVVNKRNGKKMGGAMAPPMKDLPRWLEENPEFAVAPDWTDIVKQSGFVPESMFDRLLTGPVVREEGASRRGRRPKSEIAKAAAAAAAVASTSGINPLLMNSLFAGMDLTSLQNLQNLQSLQLAGLMGFPPGLATAAAAGGDAKNPAAMLPLMLPGMAGLPNMFGLSGLLNNPITATTGNATTASGQGETEDGASKAEEKKNENEEENKDSEKSTDTVSATDSANGSVSAATAATTATATTTTTTNTGLPTNPLAFNPFLLSTMAPGLFYPSMFLPPGLGGLTLPGFPALAGLQNAVGSNEEKATDKTEGTAFKDEENLEGSDAEESLDKTADSSILEDEIAQGEELDSLDGGEEIENNENDE", "length": 3000, "header": "tr|A0A8V0XDW9-1|CHD7_CHICK Computationally mapped isoform of ATP-dependent chromatin remodeler CHD7 OS=Gallus gallus OX=9031 GN=CHD7 PE=2 SV=1 CANONICAL=Q06A37-1" }, "locus": { "chromosome": "2", "start_pos": 112705488, "end_pos": 112618430, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010006102.1", "url": "https://www.ensembl.org/id/ENSGALT00010006102.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010003810.1", "url": "https://www.ensembl.org/id/ENSGALP00010003810.1" } ] } }, { "isoform_ac": "Q06A37-1", "url": "https://www.uniprot.org/uniprotkb/Q06A37/entry#Q06A37-1", "sequence": { "sequence": "MADPGMMSLFGEDGNIFSEGLEGLGECGYPENTVNPMGQQMPMDQGFPSLQSSLHHPPANQNQAKLTHFDHYNQYEQQKMHLMDQPNRMISNAPGNGIASPHSQYHNPPVPQVPHGSGASGQMGVYPSMQNERHGQPFVDSGSMWGPRAVQVPDQIRAPYQQQQQQPQPTQPPQAPSGPPGQGHPQHMQQMGNYMARGDFSMQQHGQPQQQRMNQFSQGQEGLNQGNPFIATSGPGHLSHVPQQNPSMAPSLRHSVQQFHHHPPTALHGESVAHSPRFSPNPPQQGAVRPQTLNFSSRSQTVPSPTINNSGQYSRYPYSNLNQGLVNNTGMNQNLGLTNNTPMNQSVPRYPNAVGFPSNSGQGLMHQQPIHPSGSLNQMNTQTMHPSQPQGTYASPPPMSPMKAMSNPAGTPPPQVRPGSAGIPMEVGSYPNIPHPQPSHQPPGAMGIGQRNMGPRNMQQNRPFMGMSSTPREMGGHMRPNGCPGVGLADPQAIQERLISGQQLPSQQQSFQQQMPTCPPMQPHPGIHHQSSPPPHPHHQPWAQLHQSPQNTPQKVPVLQHSPSEPFLEKPVPDMTQVSGPNTQLVKSDDYLPSVEPQPQQKKKKKKNNHIAAEGPSKSFGKEDFPGGLDSQNLSRNSVDCSQEDKKKKKKPKAKKEPKDPKEPKEKKEPKTPKVPKTPKEPKEKKAKNTTPKPKTSKKTSNKKTDSESSAAKKKVNKGKEGSENSDLDKTPPPSPHPEDEDDPGVQKRRSSRQVKRKRYTEDLEFKISDEEADDADAAGRDSPSNTSQSEQQESADAEGPVVEKIMSSRSVKKKMENGEEVEIEEFYVKYKNFSYLHCQWASVEELDKDKRIQQKIKRFKAKQGQNKFLSEIDDELFNPDYVEIDRILDFSRSTDDNGEPVTHYLVKWCSLPYEDSTWELKQDIDQAKIEEFEKLMSREPEMERVERPPADDWKKSESSREYKNNNKLREYQLEGVNWLLFNWYNTRNCILADEMGLGKTIQSITFLYEIYLKGIHGPFLVIAPLSTIPNWEREFRTWTELNVVVYHGSQASRRTIQLYEMYFKDPQGRVIKGSYKFHAIITTFEMILTDCPELRNIPWRCVVIDEAHRLKNRNCKLLEGLKMMDLEHKVLLTGTPLQNTVEELFSLLHFLEPGRFPSETTFMQEFGDLKTEEQVQKLQAILKPMMLRRLKEDVEKNLAPKEETIIEVELTNIQKKYYRAILEKNFAFLSKGGGQANVPNLLNTMMELRKCCNHPYLINGAEEKILEEFKETHNADSPDFQLQAMIQAAGKLVLIDKLLPKLKAGGHRVLIFSQMVRCLDILEDYLIQRRYPYERIDGRVRGNLRQAAIDRFSRPDSDRFVFLLCTRAGGLGINLTAADTCIIFDSDWNPQNDLQAQARCHRIGQSKSVKIYRLITRNSYEREMFDKASLKLGLDKAVLQSMSGRENATNGVQQLSKKEIEDLLRKGAYGALMDEEDEGSKFCEEDIDQILLRRTHTITIESEGKGSTFAKASFVASGNRTDISLDDPNFWQKWAKKAELDIDALNGRNNLVIDTPRVRKQTRLYSAVKEDELMEFSDLESDSEEKPSTKPRRPQDKSQGYARSECFRVEKNLLVYGWGRWTDILSHGRYKRQLTEQDVETICRTILVYCLNHYKGDENIKSFIWDLITPTADGQTRALVNHSGLSAPVPRGRKGKKVKAQSSQPMLQDADWLTTCNPDVLFQEDSYRKHLKHHCNKVLLRVRMLYYLRQEVIGDQADRILEGADSSEVDVWIPEPFHAEVPADWWDKEADKSLLIGVFKHGYEKYNSMRADSTLCFLERVGMPDAKAIAAEQRGTDMLADGGDGGEFDREDEDPEYKPTRTPFKDEIDEFANSPPEDKEESIEIHPNKHSESNSELGQLYWPNTSTLTTRLRRLITAYQRSYKRQQMRQEALMKTDRRRRRPREEVRALEAEREAIITEKRQKWTRREEADFYRVVSTFGIIFDPIKHQFDWNQFRAFARLDKKSDESLEKYFNGFVNMCRRVCRMPVKPDDEPPDLSTMIEPITEERASRTLYRIELLRKIREQVLHHPQLGERLKLCQPSLDLPEWWECGKHDKDLLIGAAKHGVSRTDYHILNDPELSFLEAHKNFAQNRGTGNANTVSSLHPVGAGCSQTPPIVPSTPVQEEKSTEQTESKVEGSENPAAKEKSDIKEETDIADKDTKQDCDAEAETGSVKCELKDIEMSTDVDPKSISEKGSEEDEEEKLDDDDKSEESSQPEAGAVSQGKNFDEESNASMSTARDETRDGFYMEDGDPSVVQLLHERTFAFSFWPKDRVMINRLDNICEAVLKGKWPVNRRQMFDFQGLIPGYTPTAVDSPLQKRSFAELSMIGQASISGSEDITASPQLSKEDALNLSVPRQRRRRRRKIEIEAERAAKRRNLMEMVAQLRESQVVSENGQEKVVDLSKASREATSSTSNFSSVTSKFILPNVSTPVSDAFKTQMELLQAGLSRTPTRHLLNGSLIDGEPPMKRRRGRRKNVEGLDLLFMSNKRTSLTVEDAEVTKAFEEDMEALPARNIPSPGQLDPDTRIPVINLEDGTRLVGEDAPKNKDLVEWLKLHPTYTVDMPSYVPKSADVLFSSFQKPKQKRHRCRNPNKLDINTLTGEERVPVVNKRNGKKMGGAMAPPMKDLPRWLEENPEFAVAPDWTDIVKQSGFVPESMFDRLLTGPVVREEGASRRGRRPKSEIAKAAAAAAAVASTSGINPLLMNSLFAGMDLTSLQNLQNLQSLQLAGLMGFPPGLATAAAAGGDAKNPAAMLPLMLPGMAGLPNMFGLSGLLNNPITATTGNATTASGQGETEDGASKAEEKKNENEEENKDSEKSTDTVSATDSANGSVSAATAATTATATTTTTTNTGLPTNPLAFNPFLLSTMAPGLFYPSMFLPPGLGGLTLPGFPALAGLQNAVGSNEEKATDKTEGTAFKDEENLEGSDAEESLDKTADSSILEDEIAQGEELDSLDGGEEIENNENDE", "length": 3011, "header": "sp|Q06A37-1|CHD7_CHICK Isoform 1 of ATP-dependent chromatin remodeler CHD7 OS=Gallus gallus OX=9031 GN=CHD7 PE=2 SV=1 CANONICAL=Q06A37-1" }, "locus": { "chromosome": "2", "start_pos": 112705488, "end_pos": 112618430, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010006099.1", "url": "https://www.ensembl.org/id/ENSGALT00010006099.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010003807.1", "url": "https://www.ensembl.org/id/ENSGALP00010003807.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 170, "start_aa": "Thr", "end_pos": 170, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr170", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [ { "start_pos": 2561, "end_pos": 2561, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q06A37", "url": "https://www.uniprot.org/uniprotkb/Q06A37" } ], "site_lbl": "Ser2561" } ], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "Embryonic expression profile of chicken CHD7, the ortholog of the causative gene for CHARGE syndrome.", "journal": "Birth Defects Res. A Clin. Mol. Teratol.", "date": "2007", "authors": "Aramaki Michihiko, Kimura Tokuhiro, Udaka Toru, Kosaki Rika, Mitsuhashi Takayuki, Okada Yasunori, Takahashi Takao, Kosaki Kenjiro", "evidence": [ { "database": "UniProtKB", "id": "Q06A37", "url": "https://www.uniprot.org/uniprotkb/Q06A37" }, { "database": "RefSeq", "id": "NP_001071054", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001071054" } ], "reference": [ { "type": "PubMed", "id": "17149726", "url": "https://glygen.org/publication/PubMed/17149726" } ] }, { "title": "let-7 miRNAs inhibit CHD7 expression and control auditory-sensory progenitor cell behavior in the developing inner ear.", "journal": "Development (Cambridge, England)", "date": "2020-08-14", "authors": "Evsen Lale, Li Xiaojun, Zhang Shuran, Razin Sharjil, Doetzlhofer Angelika", "evidence": [ { "database": "RefSeq", "id": "NP_001071054", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001071054" } ], "reference": [ { "type": "PubMed", "id": "32816902", "url": "https://glygen.org/publication/PubMed/32816902" } ] } ], "pathway": [ { "id": "gga:421140", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421140", "resource": "KEGG Pathway" }, { "id": "R-GGA-9943962", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9943962", "resource": "Reactome", "description": "CHD6, CHD7, CHD8, CHD9 subfamily" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A480QH44-1", "protein_name": "ATP-dependent chromatin remodeler CHD7", "gene_name": "CHD7", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MADPGMMSLFGEDGNIFSEGLEGLGECGYPENPVNPMTQQMPIDQGFASLQPSLHHPSTNQSQTKLTHFDHYNQYEQQKMHLMDQPNRMMSNAPGNGLASPHSQYHTPPVPQVPHGGGSGGQMGVYPGMQNERHGQSFVDSGSLWGPRAVPVPDQIRAPYQPPPPPPQPQPAPSGPPGQGHPPHLQQMGGYLARGDFSMQQHGQPQPRMSQFPQGQEGLSQGNPFITTSGPGHLSHVPAQSPGVAPSRHTVQPFHHHPPTALHGESVAHSPRFSPNPPQQGAVRPQTLNFSSRSQTAPSPTLNNSGQYSRYPYSNLNQGLVNNTGMNQNLGLTNNTPMNQSVPRYPNAVGFPSNSGQGLMHQQPVHPSGSLNQMNTQTMHPSQPQGTYASPPPMSPMKALSNPAGTPPPQVRPGSAGIPMDVGSYPTVPHPPPGALGIGQRSVGPRNMQQSRPFMGMSSAPRELAGHLRPNGCPGVGLADPQALQERLLPGQQHPGQQPSFQQLPTCPPLQPHPGLHHQPSPPHPHHQPWAQLHPSPQNTPQKVPVPQHSPSEPFLEKPVPDMTQVSGPNAQLVKSDDYLPSIEQQPQQKKKKKKNNHIVAEDPSKSFGKDDVPGGVDTQELNRNSLDGSQEEKKKKKRPKAKKDPKEPKDPKEKKEPKEPKTPKAPKIPKEPKEKKAKTATPKPKSSKKSSNKKPDSEASALKKKVNKGKTEGSENSDLDKTPPPSPPPEDDEDPGVQKRRSSRQVKRKRYTEDLEFKISDEEPDDADAAGRDSPSNTSQSEQQESVDAEGPVVEKIMSSRSVKKQKESGEEVEVEEFYVKYKNFSYLHCQWASVEDLEKDKRIQQKIKRFKAKQGQNKFLSEIEDELFNPDYVEVDRIMDFARSTDDRGEPVTHYLVKWCSLPYEDSTWELRQDIDQAKIEEFEKLMSREPETERVERPPADDWKKSESSREYKNNNKLREYQLEGVNWLLFNWYNMRNCILADEMGLGKTIQSITFLYEIYLKGIHGPFLVIAPLSTIPNWEREFRTWTELNVVVYHGSQASRRTIQLYEMYFKDPQGRVIKGSYKFHAIITTFEMILTDCPELRNIPWRCVVIDEAHRLKNRNCKLLEGLKMMDLEHKVLLTGTPLQNTVEELFSLLHFLEPSRFPSETTFMQEFGDLKTEEQVQKLQAILKPMMLRRLKEDVEKNLAPKEETIIEVELTNIQKKYYRAILEKNFTFLSKGGGQANVPNLLNTMMELRKCCNHPYLINGAEEKILEEFKETHNADSPDFQLQAMIQAAGKLVLIDKLLPKLKAGGHRVLIFSQMVRCLDILEDYLIQRRYPYERIDGRVRGNLRQAAIDRFSKPDSDRFVFLLCTRAGGLGINLTAADTCIIFDSDWNPQNDLQAQARCHRIGQSKSVKIYRLITRNSYEREMFDKASLKLGLDKAVLQSMSGRENAPNGVQQLSKKEIEDLLRKGAYGALMDEEDEGSKFCEEDIDQILLRRTHTITIESEGKGSTFAKASFVASGNRTDISLDDPNFWQKWAKKAELDIDALNGRNNLVIDTPRVRKQTRLYSAVKEDELMEFSDLESDSEEKPCAKPRRPQDRSQGYARSECFRVEKNLLVYGWGRWTDILSHGRYKRQLTEQDVETICRTILVYCLNHYRGDENIKSFIWDLITPTADGQTRALVNHSGLSAPVPRGRKGKKVKAQSAHPVVQDADWLAGCNPDALFQEDSYRKHLKHHCNKVLLRVRMLYYLRQEVIGDQAEKILDGADSSEADVWIPEPFHAEVPTDWWDKEADKSLLIGVFKHGYEKYNSMRADPALCFLERVGMPDAKAIAAEQRGTDMLADGGDGGEFDREDEDPEYKPTRTPFKDEIDEFANSPPEDKEEPMEIRAPGKHGESSAEFGQLYWPNTSTLTTRLRRLITAYQRSYKRQQMRQEALMKTDRRRRRPREEVRALEAEREAIISEKRQKWTRREEADFYRVVSTFGVIFDPVKQHFDWNQFRAFARLDKKSDESLEKYFSCFVAMCRRVCRMPSKPDHEPPDLASAIEPITEERASRTLYRIELLRKIREQVLHHPQLAERLKLCQPSLDLPEWWECGRHDRDLLVGAAKHGVSRTDYHILNDPELSFLDAHKTFAQNRGAGSTSALNPLAVGFGQTPVATPAAPGQEEKTAAEGKAEEAERPEVKDEEEEAEGSGKDKKRDREAEAGAARNEPKGVEVGADTGPKSISEKGSEEDEEEKLEDDDKSEESSQPEAGAVSRGKNFDEESNASMSTARDETRDGFYMEDGDPAVAQLLHERTFAFSFWPKDRVMINRLDNICEAVLKGKWPVNRRQMFDFQGLLPGYAPPTADSPLQKRSLAELSMVGQASISGSEDLTASPQMSKEDALNLSVPRQRRRRRRKIEIEAERAAKRRNLMEMVAQLRESQVVSENGQEKVVDLSKASREATSSTSNFSSLASKFILPNVSTPVSDAFKTQMELLQAGLSRTPSRHLLNGSLVDSEPPVKRRRGRRKNVEGLDLLFMSHRRTALSAEDAEVTKAFEEDIETPPTRNIPSPGQLDPDTRIPVINLEDGTRLVGEDAPKNKDLVEWLKLHPTYTVDMPSYVPKNADVLFSSFQKPKQKRHRCRNPNKLDINTLTGEERVPVVNKRNGKKMGGAMAPPMKDLPRWLEENPEFAVAPDWTDIVKQSGFVPESMFDRLLTGPVVRGEGASRRGRRPKSEIARAAAAAAAVASTSGINPLLVNSLFAGMDLTSLQNLQNLQSLQLAGLMGFPPGLATAAAAAGGDTKNPAAVLPLMLPGVAGLPSVFGLGGLLNTPLSAAAGTSAPAAGPGEADDGTSKADEKGAEHEDENKDSEKSTDAAPAPDSANGSVGAAPGPAGLPSSPLAFNPFLLSTMAPGLFYPSMFLPPGLGGLTLPGFPALAGLQNAVGSGEEKAPDKAEGGAFQEEENAEGSDAEESLDKTAESSVLEDEMAQGEELDSLDGGDEIENNENDE", "length": 2983 }, "evidence": [ { "id": "Q06A37", "url": "https://omabrowser.org/oma/group/Q06A37/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A2AJK6-1", "protein_name": "ATP-dependent chromatin remodeler CHD7", "gene_name": "Chd7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADPGMMSLFGEDGSLFSEGLEGLGECGYPENPVNPMGQQMPIDQGFPSLQPSLHHPSPNQNQTKLTHFDHYSQYEQKMHLMDQPNRMMGSAPGNGLASPHSQYHTPPVPQVPHGGGGGGQMGVYPGIQNERHGQSFVDGGSMWGPRAVQVPDQIRAPYQQQQPQPAPSGPPAQGHPQHMQQMGSYLARGDFSMQQHGQPQQRMGQFSQGQEGLSQGSPFIATSGPGHLSHMPQQSPSMAPSLRHPVQQQFHHHPAALHGESVAHSPRFSPNPPQQGAVRPQTLNFSSRNQTVPSPTVNNSGQYSRYPYSNLNQGLVNSTGMNQNLGLTNSTPMNQSVPRYPNAVGFPSNSGQGLVHQQPIHSSGSLNQMNTQTMHPSQPQGTYASPPPMSPMKAMSNPAGTPPPQVRPGSAGMPMEVGSYPNMPHPQPSHQPPGAMGIGQRNMGPRNMQQPRSFMGMSSAPRELTGHMRPNGCPGVGLADPQAIQERLIPGQQHPGQQPSFQQLPTCPPLQPHPGLHQSSPPHPHHQPWAQLHPSPQNTPQKVPVHQHSPSEPFLEKPVPDMTQVSAQNAQLVKSDDYLPSIEQQPQQKKKKKKNNHIAAGDSSKGFGKDDFPGGVENQELRRNSLDVSQEEKKKKKRPKVKKDPKESKEPKEKKEPKTPKAPKIPKEPKEKKAKTVTPKPKSSKKSSNKKPDSEASALKKKVNKGKTEGSENSDLDKTPPPSPAPEEDEDPGVQKRRSSRQVKRKRYTEDLEFKISDEEADDADAAGRDSPSNTSQSEQQESVDAEGPVVEKIMSSRLVKKQKESGEEVEVEEFYVKYKNFSYLHCQWASVEDLEKDKRIQQKIKRFKSKQGQSKFLSEIEDDLFNPDYVEVDRIMDFARSTDDRGEPVIHYLVKWCSLPYEDSTWELKQDIDQTKIEEFEKLMSREPETERVERPPADDWKKSESSREYKNNNKLREYQLEGVNWLLFNWYNMRNCILADEMGLGKTIQSITFLYEIYLKGIHGPFLVIAPLSTIPNWEREFRTWTELNVVVYHGSQASRRTIQLYEMYFKDPQGRVIKGSYKFHAIITTFEMILTDCPELRNIPWRCVVIDEAHRLKNRNCKLLEGLKMMDLEHKVLLTGTPLQNTVEELFSLLHFLEPSRFPSETTFMQEFGDLKTEEQVQKLQAILKPMMLRRLKEDVEKNLAPKEETIIEVELTNIQKKYYRAILEKNFTFLSKGGGQANVPNLLNTMMELRKCCNHPYLINGAEEKILEEFKETHNAESPDFQLQAMIQAAGKLVLIDKLLPKLKAGGHRVLIFSQMVRCLDILEDYLIQRRYPYERIDGRVRGNLRQAAIDRFSKPDSDRFVFLLCTRAGGLGINLTAADTCIIFDSDWNPQNDLQAQARCHRIGQSKSVKIYRLITRNSYEREMFDKASLKLGLDKAVLQSMSGRENATNGVQQLSKKEIEDLLRKGAYGALMDEEDEGSKFCEEDIDQILLRRTHTITIESEGKGSTFAKASFVASGNRTDISLDDPNFWQKWAKKAELDIDALNGRNNLVIDTPRVRKQTRLYSAVKEDELMEFSDLESDSEEKPCAKPRRPQDKSQGYARSECFRVEKNLLVYGWGRWTDILSHGRYKRQLTEQDVETICRAILVYCLNHYRGDENIKSFIWDLITPTADGQTRALLNHSGLSAPVPRGRKGKKVKAQSTQPVVHDAHWLASCNPDALFQEDSYKKHLKHHCNKVLLRVRMLYYLRQEVIGDQAEKILEGADSSEADVWIPEPFHAEVPTDWWDREADKSLLIGVFKHGYEKYNSMRADPALCFLERVGMPDAKAIAAEQRGTDMLADGGDGGEFDREDEDPEYKPTRAPFKDEIDEFANSPAEDKEESMEVHSSGKHSESNAELGQLYWPNTSTLTTRLRRLITAYQRSYKRQQMRQEALMKTDRRRRRPREEVRALEAEREAIISEKRQKWTRREEADFYRVVSTFGVIFDPVKQQFDWNQFRAFARLDKKSDESLGKYFSCFVAMCRRVCRMPAKPEDEPPDLASLIEPITEERASRTLYRIELLRKIREQVLHHPQLSDRLKLCQPSLDLPEWWECGRHDRDLLVGAAKHGVSRTDYHILNDPELSFLDAHKSFAQNRGASTVPPLNTLAMGFGQTPPVISSAHVHEEKAMEQAEGKAEECEHSPAKERSDGKEEEEEAGGAKDGKQECEVEASSVKGELKGVEGSADPGSKSVSEKGSEEDEEEKLEDDDKSEESSQPEAGAVSRGKTFDEESNASLSTARDETRDGFYMEDGDASVAQLLHERTFAFSFWPKDRVMINRLDNICEAVLKGKWPVNRRQMFDFQGLVPGYPPSAVDSPLQKRSFAELSMVSQASISASEDITTSPQLSKDDALNLSVPRQRRRRRRKVEIEAERAAKRRNLMEMVAQLRESQVVSENGQEKVVDLSKASREATSSTSNFSSLTSKFILPNVSTPVSDAFKSQMELLQAGLSRTPTRHMLNGSLVDGEPPMKRRRGRRKNVEGLDLLFMSHKRTPLSAEDAEVTKAFEEDIETPPIRNIPSPGQLDPDTRIPVINLEDGTRLVGEDAPKNKDLVDWLKLHPTYTVDMPSYVPKNTDVLFSSFQKPKQKRHRCRNPNKLDINTLTGEERVPVVNKRNGKKMGGAMAPPMKDLPRWLEENPEFAVAPDWTDIVKQSGFVPESMFDRLLTGPVVRGEGASRRGRRPKSEIARAAAAAAAVASTSGINPLLVNSLFAGMDLTSLQNLQNLQSLQLAGLMGFPPGLATAATAGGDAKSPAAVLPLMLPGMAGLPNVFGLGGLLNNPLSAATGNTTTASSQGEPEDGTSKAEEKGNDNEDENRDSEKSTDTVSAADSANGSVGAATAPAALPSNPLAFNPFLLSTMAPGLFYPSMFLPPGLGGLTLPGFPALAGLQNAVGTSEEKAADKAEGGPCKDGETLEGSDAEENLDKTVESSILEDEVAQGEELDSLEGGDEIENTGNDE", "length": 2986 }, "evidence": [ { "id": "Q06A37", "url": "https://omabrowser.org/oma/group/Q06A37/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3ZAP7-1", "protein_name": "ATP-dependent chromatin remodeler CHD7", "gene_name": "Chd7", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MADPGMMSLFGEDGNIFSEGLEGLGECGYPENPVNPMGQQMPIDQGFPSLQPSLHHPSPNQNQTKLTHFDHYNQYEQKMHLMDQPNRMMGSAPGNGLASPHSQYHTPPVPQVPHGGGSGGGQMGVYPGMQNDRHGQSFVDGGSMWGPRAVQVPDQIRAPYQQQQPQPAPSGPPAQGHPQHMQQMGSYLARGDFSMQQPQQRMSQFSQGQEGLSQGSPFIATSGPGGHLSHMPQQSPNIAPSLRHPVQQQFHHHPAALHGESVAHSPRFSPNPPQQGAVRPQTLNFSSRSQTVPSPTVNNSGQYSPYPYRNLNQGLVNSTGMNQNLGLTNSTPMNQSVPRYPNAVGFPSNSGQGLMLQQPIHSSGSLNQMNTQTMHPSQPQGTYASPPPMSPMKAMSNPAGTPPPQVRPGSAGIPMDVGSYPNMPHPQPSHQPPGAMGIGQRNMGPRNIQQPRPFMGMSSTPRELTGHMRPNGCPGVGLADAQAIQERLIPGQQHPGQQPPFQQLPTCPPLQPHPGLHQSSPPHPHHQPWAQLHPSPQNTPQKVPVRQHSPSEPFLEKPVPDMTQVSGQNAQLVKSDDYLPSIEQQPQQKKKKKKNNHIAAGDPSKGFGKDDFPGGVDNQELSRNSLDASQEETKKRKRPKVKKDPKELKEPREKKEPKTPKAPKTPKEPKERKAKTVTPKPKSSKKSSNKKPDSEASALKKKVNKGKTEGSENSDLDKTPPPSPGPEEDEDPGVQKRRSSRQVKRKRYTEDLEFKISDEEADDADAAGRDSPSNTSQSEQQESVDAEGPVVEKIMSSRLVKKQKESGEEVEVEEFYVKYKNFSYLHCQWASVEDLEKDKRIQQKIKRFKSKQGQSKFLSEIEDDLFNPDYVEVDRIMDFARSTDDRGEPVTHYLVKWCSLPYEDSTWELRQDLDQAKIEEFEKLMSREPETERVERPPADDWKKSESSREYKNNNKLREYQLEGVNWLLFNWYNMRNCILADEMGLGKTIQSITFLYEIYLKGIHGPFLVIAPLSTIPNWEREFRTWTELNVVVYHGSQASRRTIQLYEMYFKDPQGRVIKGSYKFHAIITTFEMILTDCPELRNIPWRCVVIDEAHRLKNRNCKLLEGLKMMDLEHKVLLTGTPLQNTVEELFSLLHFLEPSRFPSETTFMQEFGDLKTEEQVQKLQAILKPMMLRRLKEDVEKNLAPKEETIIEVELTNIQKKYYRAILEKNFTFLSKGGGQANVPNLLNTMMELRKCCNHPYLINGAEEKILEEFKDAHNADSPDFQLQAMIQAAGKLVLIDKLLPKLKAGGHRVLIFSQMVRCLDILEDYLIQRRYPYERIDGRVRGNLRQAAIDRFSKPDSDRFVFLLCTRAGGLGINLTAADTCIIFDSDWNPQNDLQAQARCHRIGQSKSVKIYRLITRNSYEREMFDKASLKLGLDKAVLQSMSGRENATNGVQQLSKKEIEDLLRKGAYGALMDEEDEGSKFCEEDIDQILLRRTHTITIESEGKGSTFAKASFVASGNRTDISLDDPNFWQKWAKKAELDIDALNGRNNLVIDTPRVRKQTRLYSAVKEDELMEFSDLESDSEEKPCIKPRRPQDKTQGYARSECFRVEKNLLVYGWGRWTDILSHGRYKRQLTEHDVETICRAILVYCLNHYRGDENIKSFIWDLITPTADGQTRALLNHSGLSAPVPRGRKGKKVKAQSMQPVVQDADWLASCNPDALFQEDSYKKHLKHHCNKVLLRVRMLYYLRQEVIGDQAEKILEGADSSEADVWIPEPFHAEVPADWWDKEADKSLLIGVFKHGYEKYNSMRADPALCFLERVGMPDAKAIAAEQRGTDMLADGGDGGEFDREDEDPEYKPTRAPFKDEIDEFANSPPEDKEDSMEAQSTGKHSESNAELGQLYWPNTSSLTTRLRRLITAYQRSYKRQQMRQEALMKTDRRRRRPREEVRALEAEREAIISEKRQKWTRREEADFYRVVSTFGVIFDPVKQQFDWNQFRAFARLDKKSDESLEKYFSCFVAMCRRVCRMPAKPEDEPPDLASLIEPITEERASRTLYRIELLRKIREQVLHHPQLSDRLKLCQPSLDLPEWWECGRHDRDLLVGAAKHGVSRTDYHILNDPELSFLDAHKSFAQNRGASTVPSLNTLAMGFGQAPPVIASAHAHEEKVMEQAEGKAEECEHSPAKERSDGKEEEEEAGGAKDSRQECEAEASSVKGELKGVEGSGDPGSKSVSEKGSEEDEEEKLEDDDKSEESSQPEAGAVSRGKTFDEESNASMSTARDETRDGFYMEDGDPSVAQLLHERTFAFSFWPKDRVMINRLDNICEAVLKGKWPINRRQMFDFQGLVPGYPPSTVDSPLQKRSFAELSMVSQASVSASEDITTSPQLSKDDALNLSVPRQRRRRRRKVEIEAERAAKRRNLMEMVAQLRESQVVSENGQEKVVDLSKASREATSSTSNFSSLTSKFILPNVSTPVSDAFKTQMELLQAGLSRTPTRHVLNGSLVDGEPPMKRRRGRRKNVEGLDLLFMSHKRTPLSAEDAEVTKAFEEDIETPPIRNIPSPGQLDPDTRIPVINLEDGTRLVGEEAPKNKDLVDWLKLHPMYTVDMPSYVPKNADVLFSPFQKPKQKRHRCRNPNKLDINTLTGEERVPVVNKRNGKKMGGAMAPPMKDLPRWLEENPEFAVAPDWTDIVKQSGFVPESMFDRLLTGPVVRGEGASRRGRRPKSEIARAAAAAAAVASTSGINPLLVNSLFAGMDLTSLQNLQNLQSLQLAGLMGFPPGLATAATAGGDAKGPAAVLPLMLPGMAGLPNVFGLGGLLNNPLSAATGNTTTASSQGEPEDGTSKAEEKGNDNEDENRDSEKSTDAVSAADSANGSVGAATAPAALPSNPLAFNPFLLSTMAPGLFYPSMFLPPGLGGLTLPGFPALAGLQNAVGASEEKAADKAEGGPCKDGETLEGSDAEENLDKTIESSILEDEVAQGEELDSLEGGDEIENNGNDE", "length": 2985 }, "evidence": [ { "id": "Q06A37", "url": "https://omabrowser.org/oma/group/Q06A37/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1QGL1-1", "protein_name": "Chromodomain-helicase-DNA-binding protein 7", "gene_name": "chd7", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MADPGMMSLFGDDGNLFSDELEGLGDCGYPQGQTNPMSQQMPHEHQGYGQLPPSLHLSSPAVPGQAKLGHHFDPFNQYEQPKMHPMDQQGGRMMGNGPVNGMSSPHSRYHGAQAGAGGAAGHHVYPGAQGDGRSQSFPDSGNTWGAQPMQVPEQTRPPFQQQPPQASSHQHGPAGPQGHAHQMGPFIGRGDYAIQGHNQTQTPPRMNHFPQGLPQEANHFLGHVGMTQNPGMSGPPIRHLAQPSQQHQQPNQQFLHRPGQGPVHPDSVASHNPQFPQSPSRQQQQQQQVMGGRPHQNMGFNMHNQQVPSNTVNSSGQYPPYSSYGNLNQGLANTSGMSPNLSLTTSSNSNPNAPVTQVQRYPAPAGPQRYPTPGGQQGPLHQQPIHVNQINTQPMHPAQNQATAQPKLQQHLPPPPQGSYSSPPSMSPMRNLATPAGTPPPQQVRPPSAGLATDVGGYPGVPHQSQGPMAHAQRGAGPMNAAQPLPHQQLPSHSTHPHPPTTQMYAALSPNHRATAAQGRSSTTPGGNHTEPPGPQDQRLHAQQAQCQQLQKPPLPFQQQQLQQVHTPPSIPPSQTHLAAHHQSSPPSQQAWAPTHQSPPPMQKVPHMLHSPPDPSLEIITSSKTPAMGPNLQPANCDLQQKESELKPKKKKKKKAKVSEGQECNNISSEAGGEVTALMNEGDSLITPVEKPAEKKSKKKPKEKEPKEPKEPKTPKTPKTPKTPKEPKEPKEKKVKTATPKPKSSKKPSAKKSDSESGNSTKKEAKRKREPSVTSDVEKTPPQSPEEEDDDGVQKRRSSRQVKRKRYTEDLEFRISDDDDGDDSAGPKSPTTSEQQELPDAEGPVVEKIMGMRMGKKELASGEEIEVEEFYVKFKGFSYLHCRWADIEELEKDKRIQQKIKRFRAKQALSTFVTEMDDEPFNPDYVEVDRVLDVSESTDENGELVTLYLVKWCSLPYEDSTWELKADIDQVKIEEFERVMAREPQLKRVERPPTSDWQKSESSREYKNANALREYQLEGVNWLLFNWYNTRNCILADEMGLGKTIQSITFLYEIYLKGIHGPFLVIAPLSTIPNWEREFRTWTELNVVVYHGSQASRKTIQAYEMYYRDTQGRIIKGAYKFHAVITTFEMILTDCPELRNVPWRCVIIDEAHRLKNRNCKLLEGLKMMDMEHKVLLTGTPLQNTVEELFSLLNFLEPDRFPSESTFMQEFGDLKTEEQVQKLQGILKPMMLRRLKEDVEKNLAPKEETIIEVELTNVQKKYYRAILEKNFAFLSKSGAGGGSGGGGGSNVPNLLNTMMELRKCCNHPYLINGAEEKIMEEFRETHPLDQPEFHLQAMIQAAGKLVLIDKLLPKLKAGGHRVLIFSQMVRCLDILEDYLIQRRYPYERIDGRVRGNLRQAAIDRFSRPDSDRFVFLLCTRAGGLGINLTAADTCIIFDSDWNPQNDLQAQARCHRIGQSKSVKIYRLITRNSYEREMFDKASLKLGLDKAVLQSMSGRENAANGVQQLSKKEIEDLLRKGAYGALMEEEDEGSKFCEEDIDQILQRRTQTITIESEGKGSTFAKASFVSAGNRTDISLEDPDFWQKWAKKAELDLDAINGRNNLVIDTPRVRKQTRHYSSMKEDDLMEYSELESDSEDKPIQKPRRPQDRTQGYPRSECFRVEKNLLVYGWGRWGDILSHGRFKRPLRERDVETICRALLAYCLLHYRGDENIKGFIWDLITPTEDGQSRTLTNHSGLSAPVPRGRKGKKGKLPVAQTRMPQADWLADCNPDLLLQEDSYKRHLKHHCNKVLLRVRMLYYLRQEVIGDQADRILEGTDSSELDIWIPQPFHADVPTDWWDLDADKSLLIGVFKHGYEKYNSMRADPTLCFLERVGMPDAKAIAAEQRGADMMADGVEGEEEDPEYKPLRMSFKDDLDDFTNSPLDDNNDGMDGETGEAPKLGENGKPGNLYWPPASALTARLRRLITAYQRTHKREQLRQEAMAKPDRRRRRPRDDILAMVTEGGAYVPDGAVAFMADGGAFMAKGSPFIPDSAALLADSAAYFKERRQRWTRREEADFYRVVSTFGVVYDVHRQCFDWSQFRAFARLDKKTDESLEKYYCSFVAMCKRVCRMPLKSETELPDPTIIIDPITEERASRTLYRIELLRRIREQVLPHPLLEERLSLCQPSPDLPAWWEPGRHDRDLLRGAAKHGVSRTDYHILNDPELSFLEAYRKFTQGKGVELPVIVSDPLTPLTLPKDEEVKEEQGDVTLPKVENGSIEDVKEEKSEALSPKKEVKNEEDENGLGPKQEPKEEKMEVEEKDVTEFKTDVEQVCPVDGMVEKKPMDQEPTDTLPSSEDKNAQDEKELPTGNKLSTEKASEDEEEKMDEDDKSEKSSQAEVGALSERKNFDEESNASLSTARDETNETRDCFSVDDVEPSASQMFSERSLFSFWPKDRVMINRMDNICEAVMKGKWPSNRRQFFDFPGLLPGYSSMATESPLQRRSLGDLSLVGQTSYSGSEDLTMSPQVNKDDALSLSVPRQRRRRRRKIEIEAERAAKRRNLMEMVAQLRESHAEGQAQAIDLTKALHSVSSSSSASAFPGAMASSATLKAQMELLQPGASSRPRANGSLLDTELPNRRKRGRRKNVEGLELLFMGNKRGQLSAELSDGTKAFVDGRTHLAMPSPAQKASGEGLDEGSLQGEDGSSTKDLREWLRQHPTYTMDMPGYVPKNEDLLLSQFAKPKQKRHRCRNPNKIDINTLTGEERVPVVNIRNGRKMGGAMAPPMKDLPRWLVENPEYAIAPDWTDIVKQSGFLPESMFDRLLTGPVVREEGVRRRGRRPKAEIAKATAAAQAAAAAAAAATTSGVNPLLMNGLFGSMDLTSLQGLQNLQSLQLAAGLMGFPTALGGGADAKHAAAMLPLMLPGMGGLPNMFSLGSLFGGNLAAAATATNGASSTEQAESEENSKPKTDEETKGEGDEKEEKQAEKSSETVESADATGDAAALNAAAAAAAAGMSTGTLAFNPFLLSTMAPGLFYPSMFLPPSLGGLAIPGFPQASLADLQSAVSGALGATGEDKESDKGPRTNQDPNASVADVETADNTLEDSDSEESQNKTADSSVLDDDLAGPAEEMDSMEGGMDDEDDDDDDDDDDPADEDDKSD", "length": 3140 }, "evidence": [ { "id": "Q06A37", "url": "https://omabrowser.org/oma/group/Q06A37/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q9P2D1-1", "protein_name": "ATP-dependent chromatin remodeler CHD7", "gene_name": "CHD7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MADPGMMSLFGEDGNIFSEGLEGLGECGYPENPVNPMGQQMPIDQGFASLQPSLHHPSTNQNQTKLTHFDHYNQYEQQKMHLMDQPNRMMSNTPGNGLASPHSQYHTPPVPQVPHGGSGGGQMGVYPGMQNERHGQSFVDSSSMWGPRAVQVPDQIRAPYQQQQPQPQPPQPAPSGPPAQGHPQHMQQMGSYMARGDFSMQQHGQPQQRMSQFSQGQEGLNQGNPFIATSGPGHLSHVPQQSPSMAPSLRHSVQQFHHHPSTALHGESVAHSPRFSPNPPQQGAVRPQTLNFSSRSQTVPSPTINNSGQYSRYPYSNLNQGLVNNTGMNQNLGLTNNTPMNQSVPRYPNAVGFPSNSGQGLMHQQPIHPSGSLNQMNTQTMHPSQPQGTYASPPPMSPMKAMSNPAGTPPPQVRPGSAGIPMEVGSYPNMPHPQPSHQPPGAMGIGQRNMGPRNMQQSRPFIGMSSAPRELTGHMRPNGCPGVGLGDPQAIQERLIPGQQHPGQQPSFQQLPTCPPLQPHPGLHHQSSPPHPHHQPWAQLHPSPQNTPQKVPVHQHSPSEPFLEKPVPDMTQVSGPNAQLVKSDDYLPSIEQQPQQKKKKKKNNHIVAEDPSKGFGKDDFPGGVDNQELNRNSLDGSQEEKKKKKRSKAKKDPKEPKEPKEKKEPKEPKTPKAPKIPKEPKEKKAKTATPKPKSSKKSSNKKPDSEASALKKKVNKGKTEGSENSDLDKTPPPSPPPEEDEDPGVQKRRSSRQVKRKRYTEDLEFKISDEEADDADAAGRDSPSNTSQSEQQESVDAEGPVVEKIMSSRSVKKQKESGEEVEIEEFYVKYKNFSYLHCQWASIEDLEKDKRIQQKIKRFKAKQGQNKFLSEIEDELFNPDYVEVDRIMDFARSTDDRGEPVTHYLVKWCSLPYEDSTWERRQDIDQAKIEEFEKLMSREPETERVERPPADDWKKSESSREYKNNNKLREYQLEGVNWLLFNWYNMRNCILADEMGLGKTIQSITFLYEIYLKGIHGPFLVIAPLSTIPNWEREFRTWTELNVVVYHGSQASRRTIQLYEMYFKDPQGRVIKGSYKFHAIITTFEMILTDCPELRNIPWRCVVIDEAHRLKNRNCKLLEGLKMMDLEHKVLLTGTPLQNTVEELFSLLHFLEPSRFPSETTFMQEFGDLKTEEQVQKLQAILKPMMLRRLKEDVEKNLAPKEETIIEVELTNIQKKYYRAILEKNFTFLSKGGGQANVPNLLNTMMELRKCCNHPYLINGAEEKILEEFKETHNAESPDFQLQAMIQAAGKLVLIDKLLPKLKAGGHRVLIFSQMVRCLDILEDYLIQRRYPYERIDGRVRGNLRQAAIDRFSKPDSDRFVFLLCTRAGGLGINLTAADTCIIFDSDWNPQNDLQAQARCHRIGQSKSVKIYRLITRNSYEREMFDKASLKLGLDKAVLQSMSGRENATNGVQQLSKKEIEDLLRKGAYGALMDEEDEGSKFCEEDIDQILLRRTHTITIESEGKGSTFAKASFVASGNRTDISLDDPNFWQKWAKKAELDIDALNGRNNLVIDTPRVRKQTRLYSAVKEDELMEFSDLESDSEEKPCAKPRRPQDKSQGYARSECFRVEKNLLVYGWGRWTDILSHGRYKRQLTEQDVETICRTILVYCLNHYKGDENIKSFIWDLITPTADGQTRALVNHSGLSAPVPRGRKGKKVKAQSTQPVVQDADWLASCNPDALFQEDSYKKHLKHHCNKVLLRVRMLYYLRQEVIGDQADKILEGADSSEADVWIPEPFHAEVPADWWDKEADKSLLIGVFKHGYEKYNSMRADPALCFLERVGMPDAKAIAAEQRGTDMLADGGDGGEFDREDEDPEYKPTRTPFKDEIDEFANSPSEDKEESMEIHATGKHSESNAELGQLYWPNTSTLTTRLRRLITAYQRSYKRQQMRQEALMKTDRRRRRPREEVRALEAEREAIISEKRQKWTRREEADFYRVVSTFGVIFDPVKQQFDWNQFRAFARLDKKSDESLEKYFSCFVAMCRRVCRMPVKPDDEPPDLSSIIEPITEERASRTLYRIELLRKIREQVLHHPQLGERLKLCQPSLDLPEWWECGRHDRDLLVGAAKHGVSRTDYHILNDPELSFLDAHKNFAQNRGAGNTSSLNPLAVGFVQTPPVISSAHIQDERVLEQAEGKVEEPENPAAKEKCEGKEEEEETDGSGKESKQECEAEASSVKNELKGVEVGADTGSKSISEKGSEEDEEEKLEDDDKSEESSQPEAGAVSRGKNFDEESNASMSTARDETRDGFYMEDGDPSVAQLLHERTFAFSFWPKDRVMINRLDNICEAVLKGKWPVNRRQMFDFQGLIPGYTPTTVDSPLQKRSFAELSMVGQASISGSEDITTSPQLSKEDALNLSVPRQRRRRRRKIEIEAERAAKRRNLMEMVAQLRESQVVSENGQEKVVDLSKASREATSSTSNFSSLSSKFILPNVSTPVSDAFKTQMELLQAGLSRTPTRHLLNGSLVDGEPPMKRRRGRRKNVEGLDLLFMSHKRTSLSAEDAEVTKAFEEDIETPPTRNIPSPGQLDPDTRIPVINLEDGTRLVGEDAPKNKDLVEWLKLHPTYTVDMPSYVPKNADVLFSSFQKPKQKRHRCRNPNKLDINTLTGEERVPVVNKRNGKKMGGAMAPPMKDLPRWLEENPEFAVAPDWTDIVKQSGFVPESMFDRLLTGPVVRGEGASRRGRRPKSEIARAAAAAAAVASTSGINPLLVNSLFAGMDLTSLQNLQNLQSLQLAGLMGFPPGLATAATAGGDAKNPAAVLPLMLPGMAGLPNVFGLGGLLNNPLSAATGNTTTASSQGEPEDSTSKGEEKGNENEDENKDSEKSTDAVSAADSANGSVGAATAPAGLPSNPLAFNPFLLSTMAPGLFYPSMFLPPGLGGLTLPGFPALAGLQNAVGSSEEKAADKAEGGPFKDGETLEGSDAEESLDKTAESSLLEDEIAQGEELDSLDGGDEIENNENDE", "length": 2997 }, "evidence": [ { "id": "Q06A37", "url": "https://omabrowser.org/oma/group/Q06A37/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 25, "go_terms": [ { "name": "cranial nerve development", "id": "GO:0021545", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021545", "evidence": [ { "database": "UniProtKB", "id": "Q06A37", "url": "https://www.uniprot.org/uniprotkb/Q06A37" } ], "pmid": "" }, { "name": "nose development", "id": "GO:0043584", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043584", "evidence": [ { "database": "UniProtKB", "id": "Q06A37", "url": "https://www.uniprot.org/uniprotkb/Q06A37" } ], "pmid": "" }, { "name": "genitalia development", "id": "GO:0048806", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048806", "evidence": [ { "database": "UniProtKB", "id": "Q06A37", "url": "https://www.uniprot.org/uniprotkb/Q06A37" } ], "pmid": "" }, { "name": "regulation of growth hormone secretion", "id": "GO:0060123", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060123", "evidence": [ { "database": "UniProtKB", "id": "Q06A37", "url": "https://www.uniprot.org/uniprotkb/Q06A37" } ], "pmid": "" }, { "name": "chromatin remodeling", "id": "GO:0006338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006338", "evidence": [ { "database": "UniProtKB", "id": "Q06A37", "url": "https://www.uniprot.org/uniprotkb/Q06A37" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "Q06A37", "url": "https://www.uniprot.org/uniprotkb/Q06A37" } ], "pmid": "" }, { "name": "inner ear morphogenesis", "id": "GO:0042472", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042472", "evidence": [ { "database": "UniProtKB", "id": "Q06A37", "url": "https://www.uniprot.org/uniprotkb/Q06A37" } ], "pmid": "" }, { "name": "cognition", "id": 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"UniProtKB", "id": "Q06A37", "url": "https://www.uniprot.org/uniprotkb/Q06A37" } ], "pmid": "" }, { "name": "chromatin organization", "id": "GO:0006325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006325", "evidence": [ { "database": "UniProtKB", "id": "Q06A37", "url": "https://www.uniprot.org/uniprotkb/Q06A37" } ], "pmid": "" }, { "name": "roof of mouth development", "id": "GO:0060021", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060021", "evidence": [ { "database": "UniProtKB", "id": "Q06A37", "url": "https://www.uniprot.org/uniprotkb/Q06A37" } ], "pmid": "" }, { "name": "head development", "id": "GO:0060322", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060322", "evidence": [ { "database": "UniProtKB", "id": "Q06A37", "url": "https://www.uniprot.org/uniprotkb/Q06A37" } ], "pmid": "" }, { "name": "camera-type eye development", "id": "GO:0043010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043010", "evidence": [ { "database": "UniProtKB", "id": "Q06A37", "url": 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The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q06A37-1" ], "evidence": [ { "id": "R-GGA-9944087", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9944087" } ] }, { "id": "R-GGA-9944450", "name": "CHD7 and CHD8 bind FAM124B", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. 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"A0A1D5P5I0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P5I0" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A1D5P5I0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P5I0" } ] } ] }, { "uniprot_ac": "A0A1D5PD32", "gene_name": "DDX17", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5PD32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PD32" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A1D5PD32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PD32" } ] } ] }, { "uniprot_ac": "A0A1D5PHB6", "gene_name": "DHX36", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5PHB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PHB6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A1D5PHB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PHB6" } ] } ] }, { "uniprot_ac": "A0A1D5PIN7", "gene_name": "DHX30", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5PIN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PIN7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A1D5PIN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PIN7" } ] } ] }, { "uniprot_ac": "A0A1D5PRR9", "gene_name": "FANCM", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5PRR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRR9" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A1D5PRR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRR9" } ] } ] }, { "uniprot_ac": "A0A1D5PS27", "gene_name": "ENTPD2", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "A0A1D5PS27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PS27" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "A0A1D5PS27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PS27" } ] } ] }, { "uniprot_ac": "A0A1D5PVS9", "gene_name": "ENTPD3", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "A0A1D5PVS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PVS9" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "A0A1D5PVS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PVS9" } ] } ] }, { "uniprot_ac": "A0A3S5ZPN3", "gene_name": "DDX5", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3S5ZPN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPN3" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A3S5ZPN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPN3" } ] } ] }, { "uniprot_ac": "A0A8V0X600", "gene_name": "DDX43", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0X600", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X600" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0X600", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X600" } ] } ] }, { "uniprot_ac": "A0A8V0X655", "gene_name": "DHX32", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0X655", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X655" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0X655", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X655" } ] } ] }, { "uniprot_ac": "A0A8V0X9Y7", "gene_name": "CFTR", "activity": [ { "ec_number": "5.6.1.6", "activity": "ATP + H2O + closed Cl(-) channel = ADP + phosphate + open Cl(-) channel.", "evidence": [ { "id": "A0A8V0X9Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X9Y7" } ] }, { "ec_number": "5.6.1.6", "activity": "", "evidence": [ { "id": "A0A8V0X9Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X9Y7" } ] } ] }, { "uniprot_ac": "A0A8V0X9Z6", "gene_name": "MOV10L1", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0X9Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X9Z6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0X9Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X9Z6" } ] } ] }, { "uniprot_ac": "A0A8V0XEC4", "gene_name": "DDX10", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XEC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEC4" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0XEC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEC4" } ] } ] }, { "uniprot_ac": "A0A8V0XG98", "gene_name": "HELQ", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XG98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XG98" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A8V0XG98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XG98" } ] } ] }, { "uniprot_ac": "A0A8V0XGV3", "gene_name": "DDX3X", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XGV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XGV3" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0XGV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XGV3" } ] } ] }, { "uniprot_ac": "A0A8V0XHD1", "gene_name": "AQR", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XHD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XHD1" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0XHD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XHD1" } ] } ] }, { "uniprot_ac": "A0A8V0XI26", "gene_name": "DDX1", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XI26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XI26" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0XI26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XI26" } ] } ] }, { "uniprot_ac": "A0A8V0XJV9", "gene_name": "SPATA5", "activity": [ { "ec_number": "3.6.4.6", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XJV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJV9" } ] }, { "ec_number": "3.6.4.6", "activity": "", "evidence": [ { "id": "A0A8V0XJV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJV9" } ] }, { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XJV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJV9" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "A0A8V0XJV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJV9" } ] } ] }, { "uniprot_ac": "A0A8V0XLC7", "gene_name": "MCM4", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XLC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLC7" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0A8V0XLC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLC7" } ] } ] }, { "uniprot_ac": "A0A8V0XMP8", "gene_name": "ZGRF1", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "A0A8V0XMP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMP8" } ] }, { "ec_number": "5.6.2.3", "activity": "", "evidence": [ { "id": "A0A8V0XMP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMP8" } ] } ] }, { "uniprot_ac": "A0A8V0XT73", "gene_name": "FBXO18", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XT73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XT73" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A8V0XT73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XT73" } ] } ] }, { "uniprot_ac": "A0A8V0XX13", "gene_name": "LOC101748706", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XX13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XX13" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A8V0XX13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XX13" } ] } ] }, { "uniprot_ac": "A0A8V0XZB8", "gene_name": "DHX34", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XZB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XZB8" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0XZB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XZB8" } ] } ] }, { "uniprot_ac": "A0A8V0Y005", "gene_name": "HSPA9", "activity": [ { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0Y005", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y005" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "A0A8V0Y005", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y005" } ] } ] }, { "uniprot_ac": "A0A8V0Y0A4", "gene_name": "AK6", "activity": [ { "ec_number": "2.7.4.3", "activity": "AMP + ATP = 2 ADP.", "evidence": [ { "id": "A0A8V0Y0A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y0A4" } ] }, { "ec_number": "2.7.4.3", "activity": "", "evidence": [ { "id": "A0A8V0Y0A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y0A4" } ] } ] }, { "uniprot_ac": "A0A8V0Y1J8", "gene_name": "YTHDC2", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0Y1J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y1J8" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0Y1J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y1J8" } ] } ] }, { "uniprot_ac": "A0A8V0Y242", "gene_name": "DDX41", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0Y242", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y242" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0Y242", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y242" } ] } ] }, { "uniprot_ac": "A0A8V0YAA4", "gene_name": "XRCC6", "activity": [ { "ec_number": "4.2.99.18", "activity": "2'-deoxyribonucleotide-(2'-deoxyribose 5'-phosphate)-2'-deoxyribonucleotide-DNA = a 3'-end 2'-deoxyribonucleotide-(2,3-dehydro-2,3-deoxyribose 5'-phosphate)-DNA + a 5'-end 5'-phospho-2'-deoxyribonucleoside-DNA + H(+).", "evidence": [ { "id": "A0A8V0YAA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAA4" } ] }, { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YAA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAA4" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A8V0YAA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAA4" } ] }, { "ec_number": "4.2.99.18", "activity": "", "evidence": [ { "id": "A0A8V0YAA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAA4" } ] } ] }, { "uniprot_ac": "A0A8V0YCY8", "gene_name": "RIOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YCY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YCY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY8" } ] } ] }, { "uniprot_ac": "A0A8V0YFB8", "gene_name": "ATP13A4", "activity": [ { "ec_number": "7.2.2.-", "activity": "", "evidence": [ { "id": "A0A8V0YFB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFB8" } ] } ] }, { "uniprot_ac": "A0A8V0YFG2", "gene_name": "ATP13A5", "activity": [ { "ec_number": "7.2.2.-", "activity": "", "evidence": [ { "id": "A0A8V0YFG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFG2" } ] } ] }, { "uniprot_ac": "A0A8V0YGQ1", "gene_name": "DDX59", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YGQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGQ1" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0YGQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGQ1" } ] } ] }, { "uniprot_ac": "A0A8V0YHC8", "gene_name": "VCP", "activity": [ { "ec_number": "3.6.4.6", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YHC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHC8" } ] }, { "ec_number": "3.6.4.6", "activity": "", "evidence": [ { "id": "A0A8V0YHC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHC8" } ] } ] }, { "uniprot_ac": "A0A8V0YLC1", "gene_name": "DDX11", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "A0A8V0YLC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLC1" } ] }, { "ec_number": "5.6.2.3", "activity": "", "evidence": [ { "id": "A0A8V0YLC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLC1" } ] } ] }, { "uniprot_ac": "A0A8V0YLM0", "gene_name": "RECQL", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YLM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLM0" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A8V0YLM0", "database": "UniProtKB", "url": 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"ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZEN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEN5" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0ZEN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEN5" } ] } ] }, { "uniprot_ac": "A0A8V0ZFN9", "gene_name": "DDX54", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZFN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFN9" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0ZFN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFN9" } ] } ] }, { "uniprot_ac": "A0A8V0ZIP8", "gene_name": "XRCC5", "activity": [ { "ec_number": "4.2.99.18", "activity": "2'-deoxyribonucleotide-(2'-deoxyribose 5'-phosphate)-2'-deoxyribonucleotide-DNA = a 3'-end 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} ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0ZPM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPM1" } ] } ] }, { "uniprot_ac": "A0A8V0ZPN6", "gene_name": "INO80", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "A0A8V0ZPN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPN6" } ] } ] }, { "uniprot_ac": "A0A8V0ZR10", "gene_name": "PIF1", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "A0A8V0ZR10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR10" } ] }, { "ec_number": "5.6.2.3", "activity": "", "evidence": [ { "id": "A0A8V0ZR10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR10" } ] } ] }, { "uniprot_ac": "A0A8V0ZS56", "gene_name": "HFM1", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZS56", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS56" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A8V0ZS56", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS56" } ] } ] }, { "uniprot_ac": "A0A8V0ZTR5", "gene_name": "LOC423693", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZTR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTR5" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0ZTR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTR5" } ] } ] }, { "uniprot_ac": "A0A8V0ZU49", "gene_name": "DNA2", "activity": [ { "ec_number": "3.1.-.-", "activity": "", "evidence": [ { "id": "A0A8V0ZU49", "database": "UniProtKB", "url": 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"id": "A0A8V0ZZK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZK3" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0ZZK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZK3" } ] } ] }, { "uniprot_ac": "A0A8V1A3M1", "gene_name": "DDX55", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1A3M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3M1" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V1A3M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3M1" } ] } ] }, { "uniprot_ac": "A0A8V1A4V3", "gene_name": "POLQ", "activity": [ { "ec_number": "2.7.7.7", "activity": "DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate.", "evidence": [ { "id": "A0A8V1A4V3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V3" } ] }, { "ec_number": "2.7.7.49", "activity": "DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate.", "evidence": [ { "id": "A0A8V1A4V3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V3" } ] }, { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1A4V3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V3" } ] }, { "ec_number": "2.7.7.7", "activity": "", "evidence": [ { "id": "A0A8V1A4V3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V3" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0A8V1A4V3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V3" } ] }, { "ec_number": "2.7.7.49", "activity": "", "evidence": [ { "id": "A0A8V1A4V3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V3" } ] } ] }, { "uniprot_ac": "A0A8V1A5D6", "gene_name": "DDX51", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1A5D6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5D6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V1A5D6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5D6" } ] } ] }, { "uniprot_ac": "A0A8V1A712", "gene_name": "", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1A712", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A712" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V1A712", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A712" } ] } ] }, { "uniprot_ac": "A0A8V1A7M6", "gene_name": "", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1A7M6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V1A7M6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M6" } ] } ] }, { "uniprot_ac": "A0A8V1A7P4", "gene_name": "DDX49", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1A7P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P4" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V1A7P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P4" } ] } ] }, { "uniprot_ac": "A0A8V1A8Y2", "gene_name": "ENTPD8", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "A0A8V1A8Y2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8Y2" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "A0A8V1A8Y2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8Y2" } ] } ] }, { "uniprot_ac": "A0A8V1ACD8", "gene_name": "NSF", "activity": [ { "ec_number": "3.6.4.6", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1ACD8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACD8" } ] }, { "ec_number": "3.6.4.6", "activity": "", "evidence": [ { "id": "A0A8V1ACD8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACD8" } ] } ] }, { "uniprot_ac": "A0A8V1ADZ7", "gene_name": "RHOT1", "activity": [ { "ec_number": "3.6.5.-", "activity": "", "evidence": [ { "id": "A0A8V1ADZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADZ7" } ] } ] }, { "uniprot_ac": "A0A8V1AE46", "gene_name": "ENTPD8L1", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "A0A8V1AE46", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE46" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "A0A8V1AE46", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE46" } ] } ] }, { "uniprot_ac": "A0A8V1AER6", "gene_name": "MOV10", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1AER6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AER6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V1AER6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AER6" } ] } ] }, { "uniprot_ac": "A0A8V1AFG8", "gene_name": "RECQL5", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1AFG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFG8" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A8V1AFG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFG8" } ] } ] }, { "uniprot_ac": "A0A8V1AFJ9", "gene_name": "MCM2", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1AFJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFJ9" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0A8V1AFJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFJ9" } ] } ] }, { "uniprot_ac": "A0A8V1AIK2", "gene_name": "DDX25", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1AIK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIK2" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V1AIK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIK2" } ] } ] }, { "uniprot_ac": "A0A8V1AJ43", "gene_name": "DHX40", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1AJ43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ43" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V1AJ43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ43" } ] } ] }, { "uniprot_ac": "A0A8V1AJY9", "gene_name": "DDX31", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1AJY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJY9" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V1AJY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJY9" } ] } ] }, { "uniprot_ac": "A0A8V1AKU6", "gene_name": "HELZ", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1AKU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKU6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V1AKU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKU6" } ] } ] }, { "uniprot_ac": "A0A8V1AL41", "gene_name": "DHX33", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1AL41", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL41" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V1AL41", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL41" } ] } ] }, { "uniprot_ac": "A0A8V1ALH0", "gene_name": "RNF213", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1ALH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALH0" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1ALH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALH0" } ] } ] }, { "uniprot_ac": "B6ZLK2", "gene_name": "CHD1", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "B6ZLK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B6ZLK2" } ] } ] }, { "uniprot_ac": "E1BSC0", "gene_name": "DDX46", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BSC0", "database": "UniProtKB", "url": 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"UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NA92" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "F1NA92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NA92" } ] } ] }, { "uniprot_ac": "F1ND48", "gene_name": "FBH1", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1ND48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1ND48" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "F1ND48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1ND48" } ] } ] }, { "uniprot_ac": "F1NFJ0", "gene_name": "MCM3", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1NFJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NFJ0" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "F1NFJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NFJ0" } ] } ] }, { "uniprot_ac": "F1NHI3", "gene_name": "DHX15", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1NHI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NHI3" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1NHI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NHI3" } ] } ] }, { "uniprot_ac": "F1NN44", "gene_name": "ALPL", "activity": [ { "ec_number": "3.1.3.1", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "F1NN44", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NN44" } ] }, { "ec_number": "3.1.3.1", "activity": "", "evidence": [ { "id": "F1NN44", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NN44" } ] } ] }, { "uniprot_ac": "F1NQJ3", "gene_name": "PMS2", "activity": [ { "ec_number": "3.1.-.-", 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elongase 6", "type": "synonym", "evidence": [ { "id": "NP_001026710", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026710" }, { "id": "Q5ZJR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJR8/entry#names_and_taxonomy" } ] }, { "name": "ELOVL family member 6, elongation of long chain fatty acids (FEN1/Elo2, SUR4/Elo3-like, yeast)", "type": "synonym", "evidence": [ { "id": "NP_001026710", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026710" } ] }, { "name": "ELOVL fatty acid elongase 6", "type": "synonym", "evidence": [ { "id": "Q5ZJR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJR8/entry#names_and_taxonomy" } ] }, { "name": "Elongation of very long chain fatty acids protein 6", "type": "synonym", "evidence": [ { "id": "Q5ZJR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJR8/entry#names_and_taxonomy" } ] }, { "name": "Very long chain 3-ketoacyl-CoA synthase 6", "type": "synonym", "evidence": [ { "id": "Q5ZJR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJR8/entry#names_and_taxonomy" } ] }, { "name": "Very long chain 3-oxoacyl-CoA synthase 6", "type": "synonym", "evidence": [ { "id": "Q5ZJR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJR8/entry#names_and_taxonomy" } ] }, { "name": "elongation of very long chain fatty acids family member protein 6", "type": "synonym", "evidence": [ { "id": "NP_001026710", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026710" } ] }, { "name": "elongation of very long chain fatty acids protein 6", "type": "synonym", "evidence": [ { "id": "NP_001026710", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026710" } ] }, { "name": "very long chain 3-ketoacyl-CoA synthase 6", "type": "synonym", "evidence": [ { "id": "NP_001026710", "database": "RefSeq", "url": 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The reference sequence was derived from JAENSK010000074.1. On Aug 8, 2005 this sequence version replaced XP_426328.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001026710", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026710" } ] }, { "annotation": "Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that elongates fatty acids with 12, 14 and 16 carbons with higher activity toward C16:0 acyl-CoAs. Catalyzes the synthesis of unsaturated C16 long chain fatty acids and, to a lesser extent, C18:0 and those with low desaturation degree. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0XLL5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLL5#function" }, { "database": "HAMAP", "id": "MF_03206", "url": "https://hamap.expasy.org/signature/MF_03206" }, { "database": "UniProtKB", "id": "Q5ZJR8", "url": "https://www.uniprot.org/uniprotkb/Q5ZJR8#function" } ] }, { "annotation": "Estrogen Abolishes the Repression Role of gga-miR-221-5p Targeting ELOVL6 and SQLE to Promote Lipid Synthesis in Chicken Liver. Publication Status: Online-Only", "evidence": [ { "database": "RefSeq", "id": "NP_001026710", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026710" }, { "database": "PubMed", "id": "32120850", "url": "https://glygen.org/publication/PubMed/32120850" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZJR8", "url": "https://www.uniprot.org/uniprotkb/Q5ZJR8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ELOVL6", "url": "https://www.uniprot.org/uniprotkb/Q5ZJR8", "locus": { "chromosome": "4", "start_pos": 57533467, "end_pos": 57440809, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010003790", "url": "https://www.ensembl.org/id/ENSGALG00010003790" } ] } } ], "crossref": [ { "id": "Q5ZJR8", "url": 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"categories": [ "Protein" ] }, { "id": "NP_001026710", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026710", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "32727", "url": "https://www.rhea-db.org/rhea/32727", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "35315", "url": "https://www.rhea-db.org/rhea/35315", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "36503", "url": "https://www.rhea-db.org/rhea/36503", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "36511", "url": "https://www.rhea-db.org/rhea/36511", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "36523", "url": "https://www.rhea-db.org/rhea/36523", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "39167", "url": "https://www.rhea-db.org/rhea/39167", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "39675", "url": "https://www.rhea-db.org/rhea/39675", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "60140", "url": "https://www.rhea-db.org/rhea/60140", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0XEK7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEK7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XEK7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEK7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XEL2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEL2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XEL2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEL2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XLL5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLL5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XLL5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLL5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZJR8", "url": 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"MQENWKKSFLFSALYAAFIFGGRHLMNKRAKFELRKPLVLWSLSLAVFSIFGAVRTAPYMLYILMTKGLKQSVCDQSFYIGPVSKFWAYAFVLSKAPELDTIFIILRKQKLIFLHWYHHITVLLYSWYSYKDMVAGGGWFMTMNYGVHAVMYSYYALRAAGFRVSRKFAMFITLSQITQMLVGCVINYLVFSWMQHGQCHSHVQNIIWSSLMYLSYFVLFCHFFFEAYIGKTTKARKVD", "length": 239, "header": "tr|A0A8V0XEK7-1|ELOV6_CHICK Computationally mapped isoform of Very long chain fatty acid elongase 6 OS=Gallus gallus OX=9031 GN=ELOVL6 PE=2 SV=1 CANONICAL=Q5ZJR8-1" }, "locus": { "chromosome": "4", "start_pos": 57505818, "end_pos": 57441653, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010008771.1", "url": "https://www.ensembl.org/id/ENSGALT00010008771.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010005126.1", "url": "https://www.ensembl.org/id/ENSGALP00010005126.1" } ] } }, { "isoform_ac": "A0A8V0XEL2-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZJR8/entry#A0A8V0XEL2-1", "sequence": { "sequence": "MNMSVLTLQEYEFEKQFNEHEAIQWMQENWKKSFLFSALYAAFIFGGRHLMNKRAKFELRKPLVLWSLSLAVFRWQAEAYCYVTKPCKYKAE", "length": 92, "header": "tr|A0A8V0XEL2-1|ELOV6_CHICK Computationally mapped isoform of Very long chain fatty acid elongase 6 OS=Gallus gallus OX=9031 GN=ELOVL6 PE=2 SV=1 CANONICAL=Q5ZJR8-1" }, "locus": { "chromosome": "4", "start_pos": 57533382, "end_pos": 57441578, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010008778.1", "url": "https://www.ensembl.org/id/ENSGALT00010008778.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010005132.1", "url": "https://www.ensembl.org/id/ENSGALP00010005132.1" } ] } }, { "isoform_ac": "A0A8V0XLL5-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZJR8/entry#A0A8V0XLL5-1", "sequence": { "sequence": "MKDTSVHPKKEYEFEKQFNEHEAIQWMQENWKKSFLFSALYAAFIFGGRHLMNKRAKFELRKPLVLWSLSLAVFSIFGAVRTAPYMLYILMTKGLKQSVCDQSFYIGPVSKFWAYAFVLSKAPELGDTIFIILRKQKLIFLHWYHHITVLLYSWYSYKDMVAGGGWFMTMNYGVHAVMYSYYALRAAGFRVSRKFAMFITLSQITQMLVGCVINYLVFSWMQHGQCHSHVQNIIWSSLMYLSYFVLFCHFFFEAYIGKTTKARKVD", "length": 266, "header": "tr|A0A8V0XLL5-1|ELOV6_CHICK Computationally mapped isoform of Very long chain fatty acid elongase 6 OS=Gallus gallus OX=9031 GN=ELOVL6 PE=2 SV=1 CANONICAL=Q5ZJR8-1" }, "locus": { "chromosome": "4", "start_pos": 57505818, "end_pos": 57440970, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010008773.1", "url": "https://www.ensembl.org/id/ENSGALT00010008773.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010005128.1", "url": "https://www.ensembl.org/id/ENSGALP00010005128.1" } ] } }, { "isoform_ac": "Q5ZJR8-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZJR8/entry#Q5ZJR8-1", "sequence": { "sequence": "MNMSVLTLQEYEFEKQFNEHEAIQWMQENWKKSFLFSALYAAFIFGGRHLMNKRAKFELRKPLVLWSLSLAVFSIFGAVRTAPYMLYILMTKGLKQSVCDQSFYIGPVSKFWAYAFVLSKAPELGDTIFIILRKQKLIFLHWYHHITVLLYSWYSYKDMVAGGGWFMTMNYGVHAVMYSYYALRAAGFRVSRKFAMFITLSQITQMLVGCVINYLVFSWMQHGQCHSHVQNIIWSSLMYLSYFVLFCHFFFEAYIGKTTKARKVD", "length": 265, "header": "sp|Q5ZJR8-1|ELOV6_CHICK Isoform 1 of Very long chain fatty acid elongase 6 OS=Gallus gallus OX=9031 GN=ELOVL6 PE=2 SV=1 CANONICAL=Q5ZJR8-1" }, "locus": { "chromosome": "4", "start_pos": 57505818, "end_pos": 57441578, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010008775.1", "url": "https://www.ensembl.org/id/ENSGALT00010008775.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010005129.1", "url": "https://www.ensembl.org/id/ENSGALP00010005129.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 2, "start_aa": "Asn", "end_pos": 2, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn2", "evidence": [ { "id": "Q5ZJR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJR8#ptm_processing" }, { "id": "MF_03206", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/MF_03206" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJR8", "url": "https://www.uniprot.org/uniprotkb/Q5ZJR8" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] }, { "title": "Estrogen Abolishes the Repression Role of gga-miR-221-5p Targeting ELOVL6 and SQLE to Promote Lipid Synthesis in Chicken Liver.", "journal": "International journal of molecular sciences", "date": "2020-02-27", "authors": "Zhang Ding-Ding, Wang Dan-Dan, Wang Zhang, Wang Yang-Bin, Li Guo-Xi, Sun Gui-Rong, Tian Ya-Dong, Han Rui-Li, Li Zhuan-Jian, Jiang Rui-Rui, Liu Xiao-Jun, Kang Xiang-Tao, Li Hong", "evidence": [ { "database": "RefSeq", "id": "NP_001026710", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026710" } ], "reference": [ { "type": "PubMed", "id": "32120850", "url": "https://glygen.org/publication/PubMed/32120850" } ] } ], "pathway": [ { "id": "gga:428772", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428772", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJR8", "url": "https://www.uniprot.org/uniprotkb/Q5ZJR8" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJR8", "url": "https://www.uniprot.org/uniprotkb/Q5ZJR8" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJR8", "url": "https://www.uniprot.org/uniprotkb/Q5ZJR8" } ], "pmid": "" }, { "name": "fatty acid elongase complex", "id": "GO:0009923", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009923", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJR8", "url": 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"Q5ZJR8-1" ], "evidence": [ { "id": "32727", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/32727" } ] }, { "id": "35315", "name": "", "equation": "hexadecanoyl-CoA + malonyl-CoA + H(+) = 3-oxooctadecanoyl-CoA + CO2 + CoA", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q5ZJR8-1" ], "evidence": [ { "id": "35315", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/35315" } ] }, { "id": "36503", "name": "", "equation": "(9Z,12Z)-octadecadienoyl-CoA + malonyl-CoA + H(+) = (11Z,14Z)-3-oxoicosa-11,14-dienoyl-CoA + CO2 + CoA", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q5ZJR8-1" ], "evidence": [ { "id": "36503", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/36503" } ] }, { "id": "36511", "name": "", "equation": "(9Z)-octadecenoyl-CoA + malonyl-CoA + H(+) = 3-oxo-(11Z)-eicosenoyl-CoA + CO2 + CoA", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q5ZJR8-1" ], "evidence": [ { "id": "36511", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/36511" } ] }, { "id": "36523", "name": "", "equation": "(9Z,12Z,15Z)-octadecatrienoyl-CoA + malonyl-CoA + H(+) = (11Z,14Z,17Z)-3-oxoeicosatrienoyl-CoA + CO2 + CoA", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q5ZJR8-1" ], "evidence": [ { "id": "36523", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/36523" } ] }, { "id": "39167", "name": "", "equation": "tetradecanoyl-CoA + malonyl-CoA + H(+) = 3-oxohexadecanoyl-CoA + CO2 + CoA", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q5ZJR8-1" ], "evidence": [ { "id": "39167", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/39167" } ] }, { "id": "39675", "name": "", "equation": 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"UniProtKB", "categories": [ "Protein" ] }, { "id": "P02112-1", "url": "https://www.uniprot.org/uniprotkb/P02112-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVHWTAEEKQLITGLWGKVNVAECGAEALARLLIVYPWTQRFFASFGNLSSPTAILGNPMVRAHGKKVLTSFGDAVKNLDNIKNTFSQLSELHCDKLHVDPENFRLLGDILIIVLAAHFSKDFTPECQAAWQKLVRVVAHALARKYH", "length": 147, "header": "sp|P02112-1|HBB_CHICK Isoform 1 of Hemoglobin subunit beta OS=Gallus gallus OX=9031 GN=HBB PE=1 SV=2 CANONICAL=P02112-1" }, "isoforms": [ { "isoform_ac": "A0A8V0XF06-1", "url": "https://www.uniprot.org/uniprotkb/P02112/entry#A0A8V0XF06-1", "sequence": { "sequence": "MPCRLGAPPEMQPIAGCPGKRRGPAERIKVGTQTAAHQRAIPTGARAQTSSVPTATRYPPTAAMVHWTAEEKQLITGLWGKVNVAECGAEALARLLIVYPWTQRFFASFGNLSSPTAILGNPMVRAHGKKVLTSFGDAVKNLDNIKNTFSQLSELHCDKLHVDPENFRLLGDILIIVLAAHFSKDFTPECQAAWQKLVRVVAHALARKYH", "length": 210, "header": "tr|A0A8V0XF06-1|HBB_CHICK Computationally mapped isoform of Hemoglobin subunit beta OS=Gallus gallus OX=9031 GN=HBB PE=1 SV=1 CANONICAL=P02112-1" }, "locus": { "chromosome": "1", "start_pos": 196006504, "end_pos": 196004465, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010008949.1", "url": "https://www.ensembl.org/id/ENSGALT00010008949.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010005281.1", "url": "https://www.ensembl.org/id/ENSGALP00010005281.1" } ] } }, { "isoform_ac": "A0A8V0XKH3-1", "url": "https://www.uniprot.org/uniprotkb/P02112/entry#A0A8V0XKH3-1", "sequence": { "sequence": "MWPNVGLKPWPGRSSFGHRLSCSLGRETAAVGGVCFCSPSLYRLLIVYPWTQRFFASFGNLSSPTAILGNPMVRAHGKKVLTSFGDAVKNLDNIKNTFSQLSELHCDKLHVDPENFRVRCSWLGPIPMHLQEEILPMSPRAHVWVLPIDLPMLLGELVAGFRVGGGRDREGRDQPAA", "length": 177, "header": "tr|A0A8V0XKH3-1|HBB_CHICK Computationally mapped isoform of Hemoglobin subunit beta OS=Gallus gallus OX=9031 GN=HBB PE=1 SV=1 CANONICAL=P02112-1" }, "locus": { "chromosome": "1", "start_pos": 196005749, "end_pos": 196005219, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010008942.1", "url": "https://www.ensembl.org/id/ENSGALT00010008942.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010005274.1", "url": "https://www.ensembl.org/id/ENSGALP00010005274.1" } ] } }, { "isoform_ac": "A0A8V0XM11-1", "url": "https://www.uniprot.org/uniprotkb/P02112/entry#A0A8V0XM11-1", "sequence": { "sequence": "MVHWSAEEKQLITSVWSKVNVEECGAEALARWVCSWDRLSCTLGTETTAVLGGSANGVCLCPPSLCRLLIVYPWTQRFFASFGNLSSPTAIMGNPRVRAHGKKVLSSFGEAVKNLDNIKNTYAKLSELHCDKLHVDPENFRVRCWQREPLHCAVLCFETGGAAPAVLAEYFLSGEGNIPA", "length": 180, "header": "tr|A0A8V0XM11-1|HBB_CHICK Computationally mapped isoform of Hemoglobin subunit beta OS=Gallus gallus OX=9031 GN=HBB PE=1 SV=1 CANONICAL=P02112-1" }, "locus": { "chromosome": "1", "start_pos": 196001547, "end_pos": 196001008, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010008940.1", "url": "https://www.ensembl.org/id/ENSGALT00010008940.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010005272.1", "url": "https://www.ensembl.org/id/ENSGALP00010005272.1" } ] } }, { "isoform_ac": "A0A8V0XM16-1", "url": "https://www.uniprot.org/uniprotkb/P02112/entry#A0A8V0XM16-1", "sequence": { "sequence": "MQPIAGCPGKRRGPAERIKVGTQTAAHQRAIPTGARAQTSSVPTATRYPPTAAMVHWTAEEKQLITGLWGKVNVAECGAEALARLLIVYPWTQRFFASFGNLSSPTAILGNPMVRAHGKKVLTSFGDAVKNLDNIKNTFSQLSELHCDKLHVDPENFRLLGDILIIVLAAHFSKDFTPECQAAWQKLVRVVAHALARKYH", "length": 200, "header": "tr|A0A8V0XM16-1|HBB_CHICK Computationally mapped isoform of Hemoglobin subunit beta OS=Gallus gallus OX=9031 GN=HBB PE=1 SV=1 CANONICAL=P02112-1" }, "locus": { "chromosome": "1", "start_pos": 196005966, "end_pos": 196004465, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010008946.1", "url": "https://www.ensembl.org/id/ENSGALT00010008946.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010005278.1", "url": "https://www.ensembl.org/id/ENSGALP00010005278.1" } ] } }, { "isoform_ac": "A0A8V0XM21-1", "url": "https://www.uniprot.org/uniprotkb/P02112/entry#A0A8V0XM21-1", "sequence": { "sequence": "MQPIAGCPGKRRGPAERIKVGTQTAAHQRAIPTGARAQTSSVPTATRYPPTAAMVHWTAEEKQLITGLWGKVNVAECGAEALARLLIVYPWTQRFFASFGNLSSPTAIMGNPRVRAHGKKVLSSFGEAVKNLDNIKNTYAKLSELHCDKLHVDPENFRLLGDILIIVLASHFARDFTPACQFAWQKLVNVVAHALARKYH", "length": 200, "header": "tr|A0A8V0XM21-1|HBB_CHICK Computationally mapped isoform of Hemoglobin subunit beta OS=Gallus gallus OX=9031 GN=HBB PE=1 SV=1 CANONICAL=P02112-1" }, "locus": { "chromosome": "1", "start_pos": 196005966, "end_pos": 196000018, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010008951.1", "url": "https://www.ensembl.org/id/ENSGALT00010008951.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010005283.1", "url": "https://www.ensembl.org/id/ENSGALP00010005283.1" } ] } }, { "isoform_ac": "P02112-1", "url": "https://www.uniprot.org/uniprotkb/P02112/entry#P02112-1", "sequence": { "sequence": "MVHWTAEEKQLITGLWGKVNVAECGAEALARLLIVYPWTQRFFASFGNLSSPTAILGNPMVRAHGKKVLTSFGDAVKNLDNIKNTFSQLSELHCDKLHVDPENFRLLGDILIIVLAAHFSKDFTPECQAAWQKLVRVVAHALARKYH", "length": 147, "header": "sp|P02112-1|HBB_CHICK Isoform 1 of Hemoglobin subunit beta OS=Gallus gallus OX=9031 GN=HBB PE=1 SV=2 CANONICAL=P02112-1" }, "locus": { "chromosome": "1", "start_pos": 196005807, "end_pos": 196004465, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010008945.1", "url": "https://www.ensembl.org/id/ENSGALT00010008945.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010005277.1", "url": "https://www.ensembl.org/id/ENSGALP00010005277.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The structural and functional analysis of the hemoglobin D component from chicken.", "journal": "J. Biol. Chem.", "date": "1999", "authors": "Knapp J E, Oliveira M A, Xie Q, Ernst S R, Riggs A F, Hackert M L", "evidence": [ { "database": "UniProtKB", "id": "P02112", "url": "https://www.uniprot.org/uniprotkb/P02112" } ], "reference": [ { "type": "PubMed", "id": "10037733", "url": "https://glygen.org/publication/PubMed/10037733" } ] }, { "title": "Molecular cloning and sequence analysis of adult chicken betal globin cDNA.", "journal": "Nucleic Acids Res.", "date": "1979", "authors": "Richards R I, Shine J, Ullrich A, Wells J R, Goodman H M", "evidence": [ { "database": "UniProtKB", "id": "P02112", "url": "https://www.uniprot.org/uniprotkb/P02112" } ], "reference": [ { "type": "PubMed", "id": "514809", "url": "https://glygen.org/publication/PubMed/514809" } ] }, { "title": "5' domain and nucleotide sequence of an adult chicken chromosomal beta-globin gene.", "journal": "Biochemistry", "date": "1981", "authors": "Day L E, Hirst A J, Lai E C, Mace M, Woo S L", "evidence": [ { "database": "UniProtKB", "id": "P02112", "url": "https://www.uniprot.org/uniprotkb/P02112" } ], "reference": [ { "type": "PubMed", "id": "6263308", "url": "https://glygen.org/publication/PubMed/6263308" } ] }, { "title": "Cloning of chicken globin cDNA in bacterial plasmids.", "journal": "Gene", "date": "1981", "authors": "Padayatty J, Cummings I, Manske C L, Higuchi R, Woo S, Salser W", "evidence": [ { "database": "UniProtKB", "id": "P02112", "url": "https://www.uniprot.org/uniprotkb/P02112" } ], "reference": [ { "type": "PubMed", "id": "6266925", "url": "https://glygen.org/publication/PubMed/6266925" } ] }, { "title": "Analysis of the adult chicken beta-globin gene. Nucleotide sequence of the locus, microheterogeneity at the 5'-end of beta-globin mRNA, and aberrant nuclear RNA species.", "journal": "J. Biol. Chem.", "date": "1983", "authors": "Dolan M, Dodgson J B, Engel J D", "evidence": [ { "database": "UniProtKB", "id": "P02112", "url": "https://www.uniprot.org/uniprotkb/P02112" } ], "reference": [ { "type": "PubMed", "id": "6833240", "url": "https://glygen.org/publication/PubMed/6833240" } ] }, { "title": "Peptic peptides from the beta polypeptide chain of AII component of chicken hemoglobin.", "journal": "J. 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##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000037.1. On or before Dec 14, 2021 this sequence version replaced XP_015136937.1, XP_418723.2, XP_001234819.1, XP_001234828.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001072946", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001072946" } ] }, { "annotation": "Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. 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"Protein" ] }, { "id": "A0A8V0XGA6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XGA6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P67881", "url": "https://www.uniprot.org/uniprotkb/P67881", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P67881-1", "url": "https://www.uniprot.org/uniprotkb/P67881-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGDIEKGKKIFVQKCSQCHTVEKGGKHKTGPNLHGLFGRKTGQAEGFSYTDANKNKGITWGEDTLMEYLENPKKYIPGTKMIFAGIKKKSERVDLIAYLKDATSK", "length": 105, "header": "sp|P67881-1|CYC_CHICK Isoform 1 of Cytochrome c OS=Gallus gallus OX=9031 GN=CYC PE=1 SV=2 CANONICAL=P67881-1" }, "isoforms": [ { "isoform_ac": "A0A8V0XGA6-1", "url": "https://www.uniprot.org/uniprotkb/P67881/entry#A0A8V0XGA6-1", "sequence": { "sequence": "MGDIEKGKKIFVQKCSQCHTVEKGGKHKTGPNLHGLFGRKTGQAEGFSYTDANKNKGKCKAAFLSHWWFLVIVRSTETCRKQNNMNDQKQMYSFHFEVTACFFSCFFFYLFSCQVSLGVRIL", "length": 122, "header": "tr|A0A8V0XGA6-1|CYC_CHICK Computationally mapped isoform of Cytochrome c OS=Gallus gallus OX=9031 GN=CYC PE=1 SV=1 CANONICAL=P67881-1" }, "locus": { "chromosome": "2", "start_pos": 31666979, "end_pos": 31666614, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010005536.1", "url": "https://www.ensembl.org/id/ENSGALT00010005536.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010003375.1", "url": "https://www.ensembl.org/id/ENSGALP00010003375.1" } ] } }, { "isoform_ac": "P67881-1", "url": "https://www.uniprot.org/uniprotkb/P67881/entry#P67881-1", "sequence": { "sequence": "MGDIEKGKKIFVQKCSQCHTVEKGGKHKTGPNLHGLFGRKTGQAEGFSYTDANKNKGITWGEDTLMEYLENPKKYIPGTKMIFAGIKKKSERVDLIAYLKDATSK", "length": 105, "header": "sp|P67881-1|CYC_CHICK Isoform 1 of Cytochrome c OS=Gallus gallus OX=9031 GN=CYC PE=1 SV=2 CANONICAL=P67881-1" }, "locus": { "chromosome": "2", "start_pos": 31666979, "end_pos": 31666492, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010005531.1", "url": "https://www.ensembl.org/id/ENSGALT00010005531.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010003370.1", "url": "https://www.ensembl.org/id/ENSGALP00010003370.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Amino acid sequence of chicken heart cytochrome c.", "journal": "The Journal of biological chemistry", "date": "1966-01-25", "authors": "Chan S K, Margoliash E", "evidence": [ { "database": "UniProtKB", "id": "P67881", "url": "https://www.uniprot.org/uniprotkb/P67881" } ], "reference": [ { "type": "PubMed", "id": "5903744", "url": "https://glygen.org/publication/PubMed/5903744" } ] }, { "title": "Isolation and characterization of two alleles of the chicken cytochrome c gene.", "journal": "Nucleic Acids Res.", "date": "1983", "authors": "Limbach K J, Wu R", "evidence": [ { "database": "UniProtKB", "id": "P67881", "url": "https://www.uniprot.org/uniprotkb/P67881" } ], "reference": [ { "type": "PubMed", "id": "6324108", "url": "https://glygen.org/publication/PubMed/6324108" } ] } ], "pathway": [ { "id": "gga:420624", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420624", "resource": "KEGG Pathway" }, { "id": "R-GGA-111457", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-111457", "resource": "Reactome", "description": "Release of apoptotic factors from the mitochondria" }, { "id": "R-GGA-111458", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-111458", "resource": "Reactome", "description": "Formation of apoptosome" }, { "id": "R-GGA-111459", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-111459", "resource": "Reactome", "description": "Activation of caspases through apoptosome-mediated cleavage" }, { "id": "R-GGA-111461", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-111461", "resource": "Reactome", "description": "Cytochrome c-mediated apoptotic response" }, { "id": "R-GGA-2151201", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2151201", "resource": "Reactome", "description": "Transcriptional activation of mitochondrial biogenesis" }, { "id": "R-GGA-3299685", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3299685", "resource": "Reactome", "description": "Detoxification of Reactive Oxygen Species" }, { "id": "R-GGA-5620971", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5620971", "resource": "Reactome", "description": "Pyroptosis" }, { "id": "R-GGA-5628897", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5628897", "resource": "Reactome", "description": "TP53 Regulates Metabolic Genes" }, { "id": "R-GGA-611105", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-611105", "resource": "Reactome", "description": "Respiratory electron transport" }, { "id": "R-GGA-9627069", "name": "", 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"count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { 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"type": "synonym", "evidence": [ { "id": "P48800", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48800/entry#names_and_taxonomy" } ] }, { "name": "Heparin-binding growth factor 2", "type": "synonym", "evidence": [ { "id": "P48800", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48800/entry#names_and_taxonomy" } ] }, { "name": "bFGF", "type": "synonym", "evidence": [ { "id": "P48800", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48800/entry#names_and_taxonomy" } ] }, { "name": "basic fibroblast growth factor", "type": "synonym", "evidence": [ { "id": "NP_990764", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990764" } ] }, { "name": "fibroblast growth factor 2 (basic)", "type": "synonym", "evidence": [ { "id": "NP_990764", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990764" } ] }, { "name": "fibroblast growth factor 2", "type": "synonym", "evidence": [ { "id": "NP_990764", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990764" } ] }, { "name": "heparin-binding growth factor 2", "type": "synonym", "evidence": [ { "id": "NP_990764", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990764" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: BI391135.1, M95707.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992604, SAMN06140853 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000074.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.", "evidence": [ { "database": "RefSeq", "id": "NP_990764", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990764" } ] }, { "annotation": "Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4 (By similarity). Also acts as an integrin ligand which is required for FGF2 signaling (By similarity). Plays an important role in the regulation of cell survival, cell division, cell differentiation and cell migration (By similarity). Functions as a potent mitogen in vitro (By similarity). Can induce angiogenesis (By similarity).", "evidence": [ { "database": "UniProtKB", "id": "P48800", "url": "https://www.uniprot.org/uniprotkb/P48800#function" }, { "database": "UniProtKB", "id": "P09038", "url": "https://www.uniprot.org/uniprotkb/P09038#function" } ] }, { "annotation": "BFGF or VEGF gene therapy corrects insufficiency in the intrinsic healing capacity of tendons. Publication Status: Online-Only", "evidence": [ { "database": "RefSeq", "id": "NP_990764", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990764" }, { "database": "PubMed", "id": "26865366", "url": "https://glygen.org/publication/PubMed/26865366" } ] }, { "annotation": "Collectively, these studies show that FGF signaling up-regulates expression of alphaA-crystallin both directly and indirectly via up-regulation of c-Maf.", "evidence": [ { "database": "RefSeq", "id": "NP_990764", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990764" }, { "database": "PubMed", "id": "26719333", "url": "https://glygen.org/publication/PubMed/26719333" } ] }, { "annotation": "LIF and bFGF enhanced chicken primordial follicle activation by Wnt/beta-catenin pathway.", "evidence": [ { "database": "RefSeq", "id": "NP_990764", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990764" }, { "database": "PubMed", "id": "34555602", "url": "https://glygen.org/publication/PubMed/34555602" } ] }, { "annotation": "Synthesis increased in embryonic ventricular cardiomyocytes in response to increased stretch due to pressure overload", "evidence": [ { "database": "RefSeq", "id": "NP_990764", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990764" }, { "database": "PubMed", "id": "27070743", "url": "https://glygen.org/publication/PubMed/27070743" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "P48800", "url": "https://www.uniprot.org/uniprotkb/P48800" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FGF2", "url": "https://www.uniprot.org/uniprotkb/P48800", "locus": { "chromosome": "4", "start_pos": 53088597, "end_pos": 53117129, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010004219", "url": 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"database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9839397", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9839397", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_990764", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990764", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0XGB5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XGB5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XGB5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XGB5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XJ05", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJ05", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XJ05-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJ05-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XLT3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLT3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XLT3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLT3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P48800", "url": "https://www.uniprot.org/uniprotkb/P48800", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P48800-1", "url": "https://www.uniprot.org/uniprotkb/P48800-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAGAAGSITTLPALPDDGGGGAFPPGHFKDPKRLYCKNGGFFLRINPDGRVDGVREKSDPHIKLQLQAEERGVVSIKGVSANRFLAMKEDGRLLALKCATEECFFFERLESNNYNTYRSRKYSDWYVALKRTGQYKPGPKTGPGQKAILFLPMSAKS", "length": 158, "header": "sp|P48800-1|FGF2_CHICK Isoform 1 of Fibroblast growth factor 2 OS=Gallus gallus OX=9031 GN=FGF2 PE=2 SV=1 CANONICAL=P48800-1" }, "isoforms": [ { "isoform_ac": "A0A8V0XGB5-1", "url": "https://www.uniprot.org/uniprotkb/P48800/entry#A0A8V0XGB5-1", "sequence": { "sequence": "MRKQRNVPLYGSVTHCFLVWHFICFIIFCCCCCSVVFVYEVTATSCAGARLLLFVCVPPAHPARVFWASGSADFSSSADVKLQLQAEERGVVSIKGVSANRFLAMKEDGRLLALKCATEECFFFERLESNNYNTYRSRKYSDWYVALKRTGQYKPGPKTGPGQKAILFLPMSAKS", "length": 175, "header": "tr|A0A8V0XGB5-1|FGF2_CHICK Computationally mapped isoform of Fibroblast growth factor 2 OS=Gallus gallus OX=9031 GN=FGF2 PE=2 SV=1 CANONICAL=P48800-1" }, "locus": { "chromosome": "4", "start_pos": 53105649, "end_pos": 53092694, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010009860.1", "url": "https://www.ensembl.org/id/ENSGALT00010009860.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010005750.1", "url": "https://www.ensembl.org/id/ENSGALP00010005750.1" } ] } }, { "isoform_ac": "A0A8V0XJ05-1", "url": "https://www.uniprot.org/uniprotkb/P48800/entry#A0A8V0XJ05-1", "sequence": { "sequence": "MSFTLTPDGHVTHSSLQHIGCSFFSCCNSLAKVFFLQVPQEGEKLFLCRSLFCGWLCCNALAFRHGNTVLLKIPESESTALHRKIWDCFCVLSRSSFVCNEWPSRTGVKLQLQAEERGVVSIKGVSANRFLAMKEDGRLLALKCATEECFFFERLESNNYNTYRSRKYSDWYVALKRTGQYKPGPKTGPGQKAILFLPMSAKS", "length": 203, "header": "tr|A0A8V0XJ05-1|FGF2_CHICK Computationally mapped isoform of Fibroblast growth factor 2 OS=Gallus gallus OX=9031 GN=FGF2 PE=2 SV=1 CANONICAL=P48800-1" }, "locus": { "chromosome": "4", "start_pos": 53099920, "end_pos": 53092694, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010009857.1", "url": "https://www.ensembl.org/id/ENSGALT00010009857.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010005748.1", "url": "https://www.ensembl.org/id/ENSGALP00010005748.1" } ] } }, { "isoform_ac": "A0A8V0XLT3-1", "url": "https://www.uniprot.org/uniprotkb/P48800/entry#A0A8V0XLT3-1", "sequence": { "sequence": "MLEMGPEPLAWISLFRSRDCSNAVIDPGTCSLGLSGVQKLSLLVNQVKLQLQAEERGVVSIKGVSANRFLAMKEDGRLLALKCATEECFFFERLESNNYNTYRSRKYSDWYVALKRTGQYKPGPKTGPGQKAILFLPMSAKS", "length": 142, "header": "tr|A0A8V0XLT3-1|FGF2_CHICK Computationally mapped isoform of Fibroblast growth factor 2 OS=Gallus gallus OX=9031 GN=FGF2 PE=2 SV=1 CANONICAL=P48800-1" }, "locus": { "chromosome": "4", "start_pos": 53104711, "end_pos": 53092694, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010009858.1", "url": "https://www.ensembl.org/id/ENSGALT00010009858.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010005749.1", "url": "https://www.ensembl.org/id/ENSGALP00010005749.1" } ] } }, { "isoform_ac": "P48800-1", "url": "https://www.uniprot.org/uniprotkb/P48800/entry#P48800-1", "sequence": { "sequence": "MAAGAAGSITTLPALPDDGGGGAFPPGHFKDPKRLYCKNGGFFLRINPDGRVDGVREKSDPHIKLQLQAEERGVVSIKGVSANRFLAMKEDGRLLALKCATEECFFFERLESNNYNTYRSRKYSDWYVALKRTGQYKPGPKTGPGQKAILFLPMSAKS", "length": 158, "header": "sp|P48800-1|FGF2_CHICK Isoform 1 of Fibroblast growth factor 2 OS=Gallus gallus OX=9031 GN=FGF2 PE=2 SV=1 CANONICAL=P48800-1" }, "locus": { "chromosome": "4", "start_pos": 53116929, "end_pos": 53092694, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010009865.1", "url": "https://www.ensembl.org/id/ENSGALT00010009865.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010005751.1", "url": "https://www.ensembl.org/id/ENSGALP00010005751.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Regulation of c-Maf and alphaA-Crystallin in Ocular Lens by Fibroblast Growth Factor Signaling.", "journal": "The Journal of biological chemistry", "date": "2016", "authors": "Xie Q, McGreal R, Harris R, Gao CY, Liu W, Reneker LW, Musil LS, Cvekl A", "evidence": [ { "database": "RefSeq", "id": "NP_990764", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990764" } ], "reference": [ { "type": "PubMed", "id": "26719333", "url": "https://glygen.org/publication/PubMed/26719333" } ] }, { "title": "Basic FGF or VEGF gene therapy corrects insufficiency in the intrinsic healing capacity of tendons.", "journal": "Scientific reports", "date": "2016-02-11", "authors": "Tang Jin Bo, Wu Ya Fang, Cao Yi, Chen Chuan Hao, Zhou You Lang, Avanessian Bella, Shimada Masaru, Wang Xiao Tian, Liu Paul Y", "evidence": [ { "database": "RefSeq", "id": "NP_990764", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990764" } ], "reference": [ { "type": "PubMed", "id": "26865366", "url": "https://glygen.org/publication/PubMed/26865366" } ] }, { "title": "Physiological role of FGF signaling in growth and remodeling of developing cardiovascular system.", "journal": "Physiological research", "date": "2016-07-18", "authors": "Krejci E, Pesevski Z, Nanka O, Sedmera D", "evidence": [ { "database": "RefSeq", "id": "NP_990764", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990764" } ], "reference": [ { "type": "PubMed", "id": "27070743", "url": "https://glygen.org/publication/PubMed/27070743" } ] }, { "title": "LIF and bFGF enhanced chicken primordial follicle activation by Wnt/\u03b2-catenin pathway.", "journal": "Theriogenology", "date": "2021-12", "authors": "Guo Changquan, Dong Juan, Ma Yanfen, Zhou Shuo, Zeng Weidong, Liu Guang, Zhang Caiqiao", "evidence": [ { "database": "RefSeq", "id": "NP_990764", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990764" } ], "reference": [ { "type": "PubMed", "id": "34555602", "url": "https://glygen.org/publication/PubMed/34555602" } ] }, { "title": "Expression of alternatively spliced bFGF first coding exons and antisense mRNAs during chicken embryogenesis.", "journal": "Dev. Biol.", "date": "1993", "authors": "Z\u00fa\u00f1iga Mej\u00eda Borja A, Meijers C, Zeller R", "evidence": [ { "database": "UniProtKB", "id": "P48800", "url": "https://www.uniprot.org/uniprotkb/P48800" } ], "reference": [ { "type": "PubMed", "id": "7683281", "url": "https://glygen.org/publication/PubMed/7683281" } ] } ], "pathway": [ { "id": "gga:396413", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:396413", "resource": "KEGG Pathway" }, { "id": "R-GGA-109704", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-109704", "resource": "Reactome", "description": "PI3K Cascade" }, { "id": "R-GGA-1257604", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1257604", "resource": "Reactome", "description": "PIP3 activates AKT signaling" }, { "id": "R-GGA-190322", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-190322", "resource": "Reactome", "description": "FGFR4 ligand binding and activation" }, { "id": "R-GGA-190370", 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interaction", "id": "GO:0090722", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090722", "evidence": [ { "database": "UniProtKB", "id": "P48800", "url": "https://www.uniprot.org/uniprotkb/P48800" } ], "pmid": "" }, { "name": "chemokine binding", "id": "GO:0019956", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019956", "evidence": [ { "database": "UniProtKB", "id": "P48800", "url": "https://www.uniprot.org/uniprotkb/P48800" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "P48800", "url": "https://www.uniprot.org/uniprotkb/P48800" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P48800", "url": "https://www.uniprot.org/uniprotkb/P48800" } ], "pmid": "" }, { "name": "nucleolus", "id": 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"HPCL1_CHICK", "mass": { "chemical_mass": 22269.0, "monoisotopic_mass": 22269.0 }, "refseq": { "ac": "NP_990565", "name": "hippocalcin-like protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990565" }, "gene_names": [ { "name": "HPCAL1", "type": "recommended", "evidence": [ { "id": "P42324", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P42324" } ] }, { "name": "HPCAL1", "type": "synonym", "evidence": [ { "id": "NP_990565", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990565" } ] }, { "name": "REM-1", "type": "synonym", "evidence": [ { "id": "NP_990565", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990565" } ] }, { "name": "REM1", "type": "synonym", "evidence": [ { "id": "NP_990565", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990565" }, { "id": "P42324", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P42324" } ] } ], "protein_names": [ { "name": "Hippocalcin-like protein 1", "type": "recommended", "evidence": [ { "id": "P42324", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P42324/entry#names_and_taxonomy" } ] }, { "name": "Protein Rem-1", "type": "synonym", "evidence": [ { "id": "P42324", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P42324/entry#names_and_taxonomy" } ] }, { "name": "hippocalcin-like protein 1", "type": "synonym", "evidence": [ { "id": "NP_990565", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990565" } ] }, { "name": "protein Rem-1", "type": "synonym", "evidence": [ { "id": "NP_990565", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990565" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: X80875.1, HAEK01015002.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000066.1. On Aug 30, 2004 this sequence version replaced XP_429292.1.", "evidence": [ { "database": "RefSeq", "id": "NP_990565", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990565" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "P42324", "url": "https://www.uniprot.org/uniprotkb/P42324" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "HPCAL1", "url": "https://www.uniprot.org/uniprotkb/P42324", "locus": { "chromosome": "3", "start_pos": 96463794, "end_pos": 96411840, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010002474", "url": "https://www.ensembl.org/id/ENSGALG00010002474" } ] } } ], "crossref": [ { "id": "P42324", "url": "https://alphafold.ebi.ac.uk/entry/P42324", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000016443", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000016443", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00051", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00051", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "396161", "url": "https://www.ncbi.nlm.nih.gov/gene/396161", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "P42324", "url": "https://www.ebi.ac.uk/intact/interactors/id:P42324*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "IPR002048", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002048", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018247", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018247", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028846", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028846", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:396161", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:396161", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RQHTEFN", "url": "https://omabrowser.org/oma/group/RQHTEFN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "P42324", "url": "https://www.orthodb.org/?gene=P42324", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23055", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23055", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23055:SF79", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23055:SF79", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13499", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13499", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:P42324", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:P42324", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_990565", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990565", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0XGU8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XGU8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XGU8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XGU8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P42324", "url": "https://www.uniprot.org/uniprotkb/P42324", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P42324-1", "url": "https://www.uniprot.org/uniprotkb/P42324-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGKQNSKLRPEVLQDLRENTEFTDHELQEWYKGFLKDCPTGHLTVEEFKKIYANFFPYGDASKFAEHVFRTFDTNGDGTIDFREFIIALSVTSRGKLEQKLKWAFSMYDLDGNGYISRGEMLEIVQAIYKMVSSVMKMPEDESTPEKRTDKIFRQMDTNNDGKLSLEEFIKGAKSDPSIVRLLQCDPSSASQF", "length": 193, "header": "sp|P42324-1|HPCL1_CHICK Isoform 1 of Hippocalcin-like protein 1 OS=Gallus gallus OX=9031 GN=HPCAL1 PE=1 SV=2 CANONICAL=P42324-1" }, "isoforms": [ { "isoform_ac": "A0A8V0XGU8-1", "url": "https://www.uniprot.org/uniprotkb/P42324/entry#A0A8V0XGU8-1", "sequence": { "sequence": "MGKQNSKLRPEVLQDLRENTEFTDHELQEWYKGFLKDCPTGHLTVEEFKKIYANFFPYGDASKFAEHVFRTFDTNGDGTIDFREFIIALSVTSRGKLEQKLKWAFSMYDLDGNGYISRGEMLEIAIYKMVSSVMKMPEDESTPEKRTDKIFRQMDTNNDGKLSLEEFIKGAKSDPSIVRLLQCDPSSASQF", "length": 191, "header": "tr|A0A8V0XGU8-1|HPCL1_CHICK Computationally mapped isoform of Hippocalcin-like protein 1 OS=Gallus gallus OX=9031 GN=HPCAL1 PE=1 SV=1 CANONICAL=P42324-1" }, "locus": { "chromosome": "3", "start_pos": 96462668, "end_pos": 96459819, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010005722.1", "url": "https://www.ensembl.org/id/ENSGALT00010005722.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010003558.1", "url": "https://www.ensembl.org/id/ENSGALP00010003558.1" } ] } }, { "isoform_ac": "P42324-1", "url": "https://www.uniprot.org/uniprotkb/P42324/entry#P42324-1", "sequence": { "sequence": "MGKQNSKLRPEVLQDLRENTEFTDHELQEWYKGFLKDCPTGHLTVEEFKKIYANFFPYGDASKFAEHVFRTFDTNGDGTIDFREFIIALSVTSRGKLEQKLKWAFSMYDLDGNGYISRGEMLEIVQAIYKMVSSVMKMPEDESTPEKRTDKIFRQMDTNNDGKLSLEEFIKGAKSDPSIVRLLQCDPSSASQF", "length": 193, "header": "sp|P42324-1|HPCL1_CHICK Isoform 1 of Hippocalcin-like protein 1 OS=Gallus gallus OX=9031 GN=HPCAL1 PE=1 SV=2 CANONICAL=P42324-1" }, "locus": { "chromosome": "3", "start_pos": 96462668, "end_pos": 96459819, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010005714.1", "url": "https://www.ensembl.org/id/ENSGALT00010005714.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010003553.1", "url": "https://www.ensembl.org/id/ENSGALP00010003553.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Rem-1, a putative direct target gene of the Myb-Ets fusion oncoprotein in haematopoietic progenitors, is a member of the recoverin family.", "journal": "Oncogene", "date": "1995", "authors": "Kraut N, Frampton J, Graf T", "evidence": [ { "database": "UniProtKB", "id": "P42324", "url": "https://www.uniprot.org/uniprotkb/P42324" } ], "reference": [ { "type": "PubMed", "id": "7700627", "url": "https://glygen.org/publication/PubMed/7700627" } ] } ], "pathway": [ { "id": "gga:396161", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:396161", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "G3I2K6-1", "protein_name": "Hippocalcin-like protein 1", "gene_name": "Hpcal1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": 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"MGCIKSKEDKGPAMKYRTDNTPEPISSHVSHYGSDSSQATQSPAIKGSAVNFNSHSMTPFGGPSGMTPFGGASSSFSAVPSPYPSTLTGGVTVFVALYDYEARTTDDLSFKKGERFQIINNTEGDWWEARSIATGKTGYIPSNYVAPADSIQAEEWYFGKMGRKDAERLLLNPGNQRGIFLVRESETTKGAYSLSIRDWDEVRGDNVKHYKIRKLDNGGYYITTRAQFESLQKLVKHYREHADGLCHKLTTVCPTVKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTKVAIKTLKPGTMMPEAFLQEAQIMKKLRHDKLVPLYAVVSEEPIYIVTEFMTKGSLLDFLKEGEGKFLKLPQLVDMAAQIADGMAYIERMNYIHRDLRAANILVGDNLVCKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMVNREVLEQVERGYRMPCPQGCPESLHELMKLCWKKDPDERPTFEYIQSFLEDYFTATEPQYQPGDNL", "length": 541, "header": "sp|P09324-1|YES_CHICK Isoform 1 of Tyrosine-protein kinase Yes OS=Gallus gallus OX=9031 GN=YES1 PE=1 SV=3 CANONICAL=P09324-1" }, "isoforms": [ { "isoform_ac": "A0A8V0XHT1-1", "url": "https://www.uniprot.org/uniprotkb/P09324/entry#A0A8V0XHT1-1", "sequence": { "sequence": "MGCIKSKEDKGPAMKYRTDNTPEPISSHVSHYGSDSSQATQSPAIKGSAVNFNSHSMTPFGGPSGMTPFGGASSSFSAVPSPYPSTLTGGVTVFVALYDYEARTTDDLSFKKGERFQIINNTEGDWWEARSIATGKTGYIPSNYVAPADSIQAEEWYFGKMGRKDAERLLLNPGNQRGIFLVRESETTKGAYSLSIRDWDEVRGDNVKHYKIRKLDNGGYYITTRAQFESLQKLVKHYREHADGLCHKLTTVCPTVKPQTQGLAKDAWEIPRESLRLEGTWNGTTKVAIKTLKPGTMMPEAFLQEAQIMKKLRHDKLVPLYAVVSEEPIYIVTEFMTKGSLLDFLKEGEGKFLKLPQLVDMAAQIADGMAYIERMNYIHRDLRAANILVGDNLVCKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMVNREVLEQVERGYRMPCPQGCPESLHELMKLCWKKDPDERPTFEYIQSFLEDYFTATEPQYQPGDNL", "length": 528, "header": "tr|A0A8V0XHT1-1|YES_CHICK Computationally mapped isoform of Tyrosine-protein kinase Yes OS=Gallus gallus OX=9031 GN=YES1 PE=1 SV=1 CANONICAL=P09324-1" }, "locus": { "chromosome": "2", "start_pos": 101548938, "end_pos": 101535257, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010008964.1", "url": "https://www.ensembl.org/id/ENSGALT00010008964.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010005289.1", "url": "https://www.ensembl.org/id/ENSGALP00010005289.1" } ] } }, { "isoform_ac": "P09324-1", "url": "https://www.uniprot.org/uniprotkb/P09324/entry#P09324-1", "sequence": { "sequence": "MGCIKSKEDKGPAMKYRTDNTPEPISSHVSHYGSDSSQATQSPAIKGSAVNFNSHSMTPFGGPSGMTPFGGASSSFSAVPSPYPSTLTGGVTVFVALYDYEARTTDDLSFKKGERFQIINNTEGDWWEARSIATGKTGYIPSNYVAPADSIQAEEWYFGKMGRKDAERLLLNPGNQRGIFLVRESETTKGAYSLSIRDWDEVRGDNVKHYKIRKLDNGGYYITTRAQFESLQKLVKHYREHADGLCHKLTTVCPTVKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTKVAIKTLKPGTMMPEAFLQEAQIMKKLRHDKLVPLYAVVSEEPIYIVTEFMTKGSLLDFLKEGEGKFLKLPQLVDMAAQIADGMAYIERMNYIHRDLRAANILVGDNLVCKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMVNREVLEQVERGYRMPCPQGCPESLHELMKLCWKKDPDERPTFEYIQSFLEDYFTATEPQYQPGDNL", "length": 541, "header": "sp|P09324-1|YES_CHICK Isoform 1 of Tyrosine-protein kinase Yes OS=Gallus gallus OX=9031 GN=YES1 PE=1 SV=3 CANONICAL=P09324-1" }, "locus": { "chromosome": "2", "start_pos": 101548938, "end_pos": 101535257, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010008965.1", "url": "https://www.ensembl.org/id/ENSGALT00010008965.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010005290.1", "url": "https://www.ensembl.org/id/ENSGALP00010005290.1" } ] } } ], "glycosylation": [], "phosphorylation": [ { "start_pos": 424, "end_pos": 424, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine; by autocatalysis", "evidence": [ { "database": "UniProtKB", "id": "P09324", "url": "https://www.uniprot.org/uniprotkb/P09324" } ], "site_lbl": "Tyr424" }, { "start_pos": 535, "end_pos": 535, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine; by CSK", "evidence": [ { "database": "UniProtKB", "id": "P09324", "url": "https://www.uniprot.org/uniprotkb/P09324" } ], "site_lbl": "Tyr535" } ], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "Molecular cloning of a family of protein kinase genes expressed in the avian embryo.", "journal": "Oncogene", "date": "1992", "authors": "Marcelle C, Eichmann A", "evidence": [ { "database": "UniProtKB", "id": "P09324", "url": "https://www.uniprot.org/uniprotkb/P09324" } ], "reference": [ { "type": "PubMed", "id": "1281306", "url": "https://glygen.org/publication/PubMed/1281306" } ] }, { "title": "The sequence of chicken c-yes and p61c-yes.", "journal": "Oncogene", "date": "1989", "authors": "Zheng X F, Podell S, Sefton B M, Kaplan P L", "evidence": [ { "database": "UniProtKB", "id": "P09324", "url": "https://www.uniprot.org/uniprotkb/P09324" } ], "reference": [ { "type": "PubMed", "id": "2464785", "url": "https://glygen.org/publication/PubMed/2464785" } ] }, { "title": "Nucleotide sequence of a cDNA for the chick yes proto-oncogene: comparison with the viral yes gene.", "journal": "Nucleic Acids Res.", "date": "1988", "authors": "Sudol M, Kieswetter C, Zhao Y H, Dorai T, Wang L H, Hanafusa H", "evidence": [ { "database": "UniProtKB", "id": "P09324", "url": "https://www.uniprot.org/uniprotkb/P09324" } ], "reference": [ { "type": "PubMed", "id": "3054816", "url": "https://glygen.org/publication/PubMed/3054816" } ] }, { "title": "Yes-associated protein (YAP65) is a proline-rich phosphoprotein that binds to the SH3 domain of the Yes proto-oncogene product.", "journal": "Oncogene", "date": "1994", "authors": "Sudol M", "evidence": [ { "database": "UniProtKB", "id": "P09324", "url": "https://www.uniprot.org/uniprotkb/P09324" } ], "reference": [ { "type": "PubMed", "id": "8035999", "url": "https://glygen.org/publication/PubMed/8035999" } ] } ], "pathway": [ { "id": "gga:396238", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:396238", "resource": "KEGG Pathway" }, { "id": "R-GGA-1227986", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1227986", "resource": "Reactome", "description": "Signaling by ERBB2" }, { "id": "R-GGA-1433557", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1433557", "resource": "Reactome", "description": "Signaling by SCF-KIT" }, { "id": "R-GGA-1433559", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1433559", "resource": "Reactome", "description": "Regulation of KIT signaling" }, { "id": "R-GGA-210990", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-210990", "resource": "Reactome", "description": "PECAM1 interactions" }, { "id": "R-GGA-389356", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-389356", "resource": "Reactome", "description": "Co-stimulation by CD28" }, { "id": "R-GGA-389513", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-389513", "resource": "Reactome", "description": "Co-inhibition by CTLA4" }, { "id": "R-GGA-3928662", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3928662", "resource": "Reactome", "description": "EPHB-mediated forward signaling" }, { "id": "R-GGA-3928663", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3928663", "resource": "Reactome", "description": "EPHA-mediated growth cone collapse" }, { "id": "R-GGA-3928665", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3928665", "resource": "Reactome", "description": "EPH-ephrin mediated repulsion of cells" }, { "id": "R-GGA-912631", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-912631", "resource": "Reactome", "description": "Regulation of signaling by CBL" } ], "orthologs": [ { "uniprot_canonical_ac": "G3IFY3-1", "protein_name": "Tyrosine-protein kinase", "gene_name": "Yes1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MGCIKSKENKSPAIKYTPENPPEPISTSASHYGTEHTTVTPTSSTKGSSVNFNSLSMTPFGGSSGVTPFGGTSSSFSVVPSSYPTGLTGGVTIFVALYDYEARTTEDLSFKKGERFQIINNTEGDWWEARSIATGKNGYIPSNYVAPADSIQAEEWYFGKMGRKDAERLLLNPGNQRGIFLVRESETTKGAYSLSIRDWDEVRGDNVKHYKIRKLDNGGYYITTRAQFDTLQKLVKHYTEHADGLCHKLTTVCPTVKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTKVAIKTLKPGTMMPEAFLQEAQIMKKLRHDKLVPLYAVVSEEPIYIVTEFMSKGSLLDFLKEGDGKYLKLPQLVDMAAQIADGMAYIERMNYIHRDLRAANILVGENLVCKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILQTELVTKGRVPYPGMVNREVLEQVERGYRMPCPQGCPESLHELMNLCWKKDPDERPTFEYIQSFLEDYFTATEPQYQPGENL", "length": 541 }, "evidence": [ { "id": "P09324", "url": "https://omabrowser.org/oma/group/P09324/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P07947-1", "protein_name": "Tyrosine-protein kinase Yes", "gene_name": "YES1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGCIKSKENKSPAIKYRPENTPEPVSTSVSHYGAEPTTVSPCPSSSAKGTAVNFSSLSMTPFGGSSGVTPFGGASSSFSVVPSSYPAGLTGGVTIFVALYDYEARTTEDLSFKKGERFQIINNTEGDWWEARSIATGKNGYIPSNYVAPADSIQAEEWYFGKMGRKDAERLLLNPGNQRGIFLVRESETTKGAYSLSIRDWDEIRGDNVKHYKIRKLDNGGYYITTRAQFDTLQKLVKHYTEHADGLCHKLTTVCPTVKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTKVAIKTLKPGTMMPEAFLQEAQIMKKLRHDKLVPLYAVVSEEPIYIVTEFMSKGSLLDFLKEGDGKYLKLPQLVDMAAQIADGMAYIERMNYIHRDLRAANILVGENLVCKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILQTELVTKGRVPYPGMVNREVLEQVERGYRMPCPQGCPESLHELMNLCWKKDPDERPTFEYIQSFLEDYFTATEPQYQPGENL", "length": 543 }, "evidence": [ { "id": "P09324", "url": "https://omabrowser.org/oma/group/P09324/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q04736-1", "protein_name": "Tyrosine-protein kinase Yes", "gene_name": "Yes1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGCIKSKENKSPAIKYTPENLTEPVSPSASHYGVEHATVAPTSSTKGASVNFNSLSMTPFGGSSGVTPFGGASSSFSVVSSSYPTGLTGGVTIFVALYDYEARTTEDLSFKKGERFQIINNTEGDWWEARSIATGKSGYIPSNYVVPADSIQAEEWYFGKMGRKDAERLLLNPGNQRGIFLVRESETTKGAYSLSIRDWDEVRGDNVKHYKIRKLDNGGYYITTRAQFDTLQKLVKHYTEHADGLCHKLTTVCPTVKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTKVAIKTLKPGTMMPEAFLQEAQIMKKLRHDKLVPLYAVVSEEPIYIVTEFMSKGSLLDFLKEGDGKYLKLPQLVDMAAQIADGMAYIERMNYIHRDLRAANILVGENLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILQTELVTKGRVPYPGMVNREVLEQVERGYRMPCPQGCPESLHELMNLCWKKDPDERPTFEYIQSFLEDYFTATEPQYQPGENL", "length": 541 }, "evidence": [ { "id": "P09324", "url": "https://omabrowser.org/oma/group/P09324/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "phosphotyrosine residue binding", "id": "GO:0001784", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001784", "evidence": [ { "database": "UniProtKB", "id": "P09324", "url": "https://www.uniprot.org/uniprotkb/P09324" } ], "pmid": "" }, { "name": "non-membrane spanning protein tyrosine kinase activity", "id": "GO:0004715", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004715", "evidence": [ { "database": "UniProtKB", "id": "P09324", "url": "https://www.uniprot.org/uniprotkb/P09324" } ], "pmid": "" }, { "name": "signaling receptor binding", "id": "GO:0005102", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005102", "evidence": [ { "database": "UniProtKB", "id": "P09324", "url": "https://www.uniprot.org/uniprotkb/P09324" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "P09324", "url": "https://www.uniprot.org/uniprotkb/P09324" } ], "pmid": "" }, { "name": "enzyme binding", "id": "GO:0019899", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019899", "evidence": [ { "database": "UniProtKB", "id": "P09324", "url": "https://www.uniprot.org/uniprotkb/P09324" } ], "pmid": "" }, { "name": "transmembrane transporter binding", "id": "GO:0044325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044325", "evidence": [ { "database": "UniProtKB", "id": "P09324", "url": "https://www.uniprot.org/uniprotkb/P09324" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "P09324", "url": "https://www.uniprot.org/uniprotkb/P09324" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "P09324", "url": "https://www.uniprot.org/uniprotkb/P09324" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P09324", "url": "https://www.uniprot.org/uniprotkb/P09324" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "P09324", "url": "https://www.uniprot.org/uniprotkb/P09324" } ], "pmid": "" }, { "name": "anchoring junction", "id": "GO:0070161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070161", "evidence": [ { "database": "UniProtKB", "id": "P09324", "url": "https://www.uniprot.org/uniprotkb/P09324" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "cell surface receptor protein tyrosine kinase signaling pathway", "id": "GO:0007169", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007169", "evidence": [ { "database": "UniProtKB", "id": "P09324", "url": "https://www.uniprot.org/uniprotkb/P09324" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "P09324", "url": "https://www.uniprot.org/uniprotkb/P09324" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 120, "end_pos": 122, "annotation": "n_glycosylation_sequon" }, { "start_pos": 295, "end_pos": 297, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "10596", "name": "", "equation": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V1ADF0-1", "F1N9Y5-1", "A0A8V0XQG0-1", "A0A8V0Y9A0-1", "A0A8V1AFM7-1", "A0A8V0Z0R8-1", "A0A8V0Z4B2-1", "A0A8V0ZBN6-1", "P09324-1", "A0A8V0XHW1-1", "A0A8V0YW12-1", "A0A8V0YUJ4-1", "A0A8V0ZSN8-1", "F1NVF2-1", "A0A8V1AKW4-1", "A0A8V0XB17-1", "A0A8V0ZC34-1", "A0A8V0YYC1-1", "A0A8V0ZND5-1", "A0A8V1ACF7-1", "A0A8V0ZP30-1", "E1BTE1-1", "Q07497-1", "A0A8V0X6E7-1", "F1NCL8-1", "A0A8V0XNF4-1", "A0A8V0XN86-1", "A0A8V0YEV0-1", "A0A8V0XQ80-1", "A0A8V0XZ82-1", "A0A8V0YZE5-1", "A0A8V0YYZ7-1", "A0A8V0YCV8-1", "A0A8V0YGR1-1", "A0A8V0YNY4-1", "A0A8V0YXM5-1", "A0A8V0YXZ9-1", "A0A3Q2UKD3-1", "A0A8V0YIT6-1", "A0A8V0YIV6-1", "R4GJW5-1", "A0A8V1A3N1-1", "A0A8V1A9R2-1", "A0A8V0ZE65-1", "A0A8V0ZER1-1", "A0A8V0ZXS7-1", "A0A8V1A7N1-1", "H9KZZ1-1", "F1NQL9-1", "A0A8V1ABP4-1", "F1NZY8-1", "Q02977-1", "A0A1D5PD64-1", "A0A8V0ZDU6-1", "A0A3Q2U1T2-1", "R4GJB8-1", "A0A3Q2U639-1", "A0A8V0X5W9-1", "E1C7Z1-1", "A0A8V0Y7Y3-1", "Q5ZIU3-1", "A0A8V0YPR4-1", "A0A8V0YT43-1", "A0A8V0Z3S3-1", "A0A8V0YJJ1-1", "A0A8V0YKP8-1", "A0A8V0YZ74-1", "A0A8V0ZWV8-1", "A0A8V1A069-1", "A0A8V1A7E0-1", "A0A8V1AEL3-1", "E1BTT3-1", "F1N996-1", "H9KZZ2-1", "E1C2C8-1", "Q05876-1", "Q90891-1", "O42422-1", "P00523-1", "P08941-1", "P13387-1", "P18460-1", "P18461-1", "P21804-1", "P28693-1", "P29318-1", "P42683-1", "P54755-1", "Q00944-1", "Q07494-1", "Q07496-1", "Q07498-1", "Q08156-1", "Q6XUX0-1", "Q75R65-1", "Q8AXY6-1", "Q8JH64-1", "Q8QHL3-1", "Q91009-1", "Q91044-1", "Q91987-1", "Q98949-1", "Q9PUF6-1", "F1NW21-1", "A0A8V0YLC3-1", "A0A8V0Z7L6-1", "F1NJX6-1", "A0A8V0YUC4-1", "F1NUX4-1", "A0A8V1A2E6-1", "E1BX69-1", "A0A8V0XPF0-1", "A0A8V0XFC9-1", "A0A8V0XBZ6-1", "A0A8V0ZRU7-1", "A0A8V0ZXD3-1", "A0A8V0YYI3-1", "A0A8V0YWW2-1", "A0A8V0YZP9-1", "A0A8V0YRJ8-1", "F1NLR7-1", "A0A8V0XCY6-1", "A0A8V1AMK9-1", "A0A8V0Z189-1", "P41239-1" ], "evidence": [ { "id": "10596", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/10596" } ] }, { "id": "R-GGA-1433418", "name": "Phosphorylation of JAK2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XHW1-1", "A0A8V0YNY4-1", "A0A8V0Z0R8-1", "A0A8V0ZDU6-1", "A0A3Q2U639-1", "P09324-1", "Q08156-1" ], "evidence": [ { "id": "R-GGA-1433418", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1433418" } ] }, { "id": "R-GGA-1433428", "name": "GRB2 is indirectly recruited to p-KIT through SHP2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XHW1-1", "Q90687-1", "A0A8V0Z0R8-1", "A0A8V0ZDU6-1", "A0A3Q2U639-1", "P09324-1", "Q08156-1" ], "evidence": [ { "id": "R-GGA-1433428", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1433428" } ] }, { "id": "R-GGA-1433451", "name": "JAK2 binds to p-KIT", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XHW1-1", "A0A8V0YNY4-1", "A0A8V0Z0R8-1", "A0A8V0ZDU6-1", "A0A3Q2U639-1", "P09324-1", "Q08156-1" ], "evidence": [ { "id": "R-GGA-1433451", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1433451" } ] }, { "id": "R-GGA-1433454", "name": "Phosphorylation of GAB2 by SFKs", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XHW1-1", "Q90687-1", "A0A8V0Z0R8-1", "A0A8V0ZDU6-1", "A0A3Q2U639-1", "P09324-1", "Q08156-1" ], "evidence": [ { "id": "R-GGA-1433454", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1433454" } ] }, { "id": "R-GGA-1433456", "name": "Recruitment of STATs", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XHW1-1", "A0A8V0YNY4-1", "A0A8V0Z0R8-1", "A0A8V0ZDU6-1", "A0A3Q2U639-1", "P09324-1", "Q08156-1" ], "evidence": [ { "id": "R-GGA-1433456", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1433456" } ] }, { "id": "R-GGA-1433488", "name": "Phosphorylation of SHP2 by SFKs", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XHW1-1", "Q90687-1", "A0A8V0Z0R8-1", "A0A8V0ZDU6-1", "A0A3Q2U639-1", "P09324-1", "Q08156-1" ], "evidence": [ { "id": "R-GGA-1433488", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1433488" } ] }, { "id": "R-GGA-1433506", "name": "Phosphorylation of APS", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XHW1-1", "A0A8V0Z0R8-1", "A0A8V0ZDU6-1", "A0A3Q2U639-1", "P09324-1", "Q08156-1" ], "evidence": [ { "id": "R-GGA-1433506", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1433506" } ] }, { "id": "R-GGA-1433514", "name": "Synthesis of PIP3 from PIP2 by PI3K", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XHW1-1", "Q90687-1", "A0A8V0Z0R8-1", "A0A8V0ZDU6-1", "A0A3Q2U639-1", "P09324-1", "Q08156-1" ], "evidence": [ { "id": "R-GGA-1433514", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1433514" } ] }, { "id": "R-GGA-1433542", "name": "Phosphorylation and activation of VAV1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [ "R-GGA-195066" ], "output_participant_list": [], "enzyme_list": [ "A0A8V0XHW1-1", "A0A8V0Z0R8-1", "A0A8V0ZDU6-1", "A0A3Q2U639-1", "P09324-1", "Q08156-1" ], "evidence": [ { "id": "R-GGA-1433542", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1433542" } ] }, { "id": "R-GGA-1470009", "name": "Phosphorylation of STATs", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XHW1-1", "A0A8V0YNY4-1", "A0A8V0Z0R8-1", "A0A8V0ZDU6-1", "A0A3Q2U639-1", "P09324-1", "Q08156-1" ], "evidence": [ { "id": "R-GGA-1470009", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1470009" } ] }, { "id": "R-GGA-1470010", "name": "Dimerization of STATs", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XHW1-1", "A0A8V0YNY4-1", "A0A8V0Z0R8-1", "A0A8V0ZDU6-1", "A0A3Q2U639-1", "P09324-1", "Q08156-1" ], "evidence": [ { "id": "R-GGA-1470010", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1470010" } ] }, { "id": "R-GGA-1470012", "name": "Disassociation and translocation of STATs to the nucleus", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, nucleoplasm, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XHW1-1", "A0A8V0YNY4-1", "A0A8V0Z0R8-1", "A0A8V0ZDU6-1", "A0A3Q2U639-1", "P09324-1", "Q08156-1" ], "evidence": [ { "id": "R-GGA-1470012", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1470012" } ] }, { "id": "R-GGA-1472121", "name": "Phosphorylation of p-KIT on Y900 by Src kinases", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XHW1-1", "A0A8V0Z0R8-1", "A0A8V0ZDU6-1", "A0A3Q2U639-1", "P09324-1", "Q08156-1" ], "evidence": [ { "id": "R-GGA-1472121", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1472121" } ] }, { "id": "R-GGA-1562641", "name": "Indirect recruitment of PI3K to KIT via p(Y)-GAB2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XHW1-1", "Q90687-1", "A0A8V0Z0R8-1", "A0A8V0ZDU6-1", "A0A3Q2U639-1", "P09324-1", "Q08156-1" ], "evidence": [ { "id": "R-GGA-1562641", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1562641" } ] }, { "id": "R-GGA-1963586", "name": "SRC family kinases phosphorylate ERBB2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XNF4-1", "A0A8V0ZXS7-1", "A0A8V1A7N1-1", "A0A8V0ZDU6-1", "A0A3Q2U639-1", "P09324-1", "A0A8V0YIT6-1" ], "evidence": [ { "id": "R-GGA-1963586", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1963586" } ] }, { "id": "R-GGA-205234", "name": "Indirect recruitment of GAB2 to p-KIT", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XHW1-1", "Q90687-1", "A0A8V0Z0R8-1", "A0A8V0ZDU6-1", "A0A3Q2U639-1", "P09324-1", "Q08156-1" ], "evidence": [ { "id": "R-GGA-205234", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-205234" } ] }, { "id": "R-GGA-205238", "name": "SHP2 interacts with p-KIT", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XHW1-1", "Q90687-1", "A0A8V0Z0R8-1", "A0A8V0ZDU6-1", "A0A3Q2U639-1", "P09324-1", "Q08156-1" ], "evidence": [ { "id": "R-GGA-205238", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-205238" } ] }, { "id": "R-GGA-205244", "name": "Recruitment of CBL to KIT", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XHW1-1", "A0A8V0ZY53-1", "A0A8V0Z0R8-1", "A0A8V0ZDU6-1", "A0A3Q2U639-1", "P09324-1", "Q08156-1" ], "evidence": [ { "id": "R-GGA-205244", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-205244" } ] }, { "id": "R-GGA-205319", "name": "Interaction of APS and p-KIT", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XHW1-1", "A0A8V0Z0R8-1", "A0A8V0ZDU6-1", "A0A3Q2U639-1", "P09324-1", "Q08156-1" ], "evidence": [ { "id": "R-GGA-205319", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-205319" } ] }, { "id": "R-GGA-210291", "name": "Phosphorylation of PECAM-1 by Fyn or Lyn or c-Src", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XHW1-1", "A0A8V0Z0R8-1", "A0A8V0ZDU6-1", "A0A3Q2U639-1", "P09324-1" ], "evidence": [ { "id": "R-GGA-210291", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-210291" } ] }, { "id": "R-GGA-388829", "name": "SHP2 phosphatase binds CTLA-4", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XHW1-1", "Q90687-1", "A0A8V0Z0R8-1", "A0A8V0ZDU6-1", "A0A3Q2U639-1", "P09324-1" ], "evidence": [ { "id": "R-GGA-388829", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-388829" } ] }, { "id": "R-GGA-388831", "name": "Phosphorylation of CD28", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XHW1-1", "A0A8V0Z0R8-1", "A0A8V0ZDU6-1", "A0A3Q2U639-1", "P09324-1" ], "evidence": [ { "id": "R-GGA-388831", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-388831" } ] }, { "id": "R-GGA-3928579", "name": "Interaction of Src family kinases with p-EPHs", "equation": "", "summary": "Src family kinases (SFKs) are one of the important components of EPH receptor-mediated axon guidance. Inhibition of SFK-mediated phosphorylation in retinal axons, abolishes EPHA-mediated repulsion in stripe and growth cone collapse assays (Knoll & Drescher 2004). Several members of the Src family, including SRC, FYN, LYN and YES, are expressed widely in the same places as EPH receptors. Autophosphorylated tyrosines in the juxtamembrane region of the EPH receptors have been shown to be critical for the association of the SRC and FYN SH2 domain (Ellis et al. 1996, Zisch et al. 1998). These SFKs are involved in the phosphorylation of RhoGEF ephexin1 and cortactin (Knoll & Drescher 2004). This event is deduced on the basis of experimental evidence from chicken assay studies (Knoll & Drescher 2004).
Specifically, activated EPHA4 was shown to form a complex with FYN and LYN kinases (Prevost et al. 2002).", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P00523-1", "P28693-1", "P09324-1", "Q05876-1", "Q07496-1" ], "evidence": [ { "id": "R-GGA-3928579", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3928579" } ] }, { "id": "R-GGA-3928596", "name": "Phosphorylation of ephexin1", "equation": "", "summary": "Activation of EPHAs leads to phosphorylation of ephexin1 (NGEF) on conserved tyrosine (Y) 179 (Y87 in isoform3) by Src family kinases (SFKs). This phosphorylation preferentially activates NGEF\u2019s GDP/GTP exchange activity specifically towards RHOA but not RAC1 and CDC42, thus switching the substrate preference of NGEF and leading to actin cytoskeletal changes that result in growth cone collapse (Sahin et al. 2005, Knoll and Drescher 2004).", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P00523-1", "P28693-1", "P09324-1", "Q05876-1", "Q07496-1" ], "evidence": [ { "id": "R-GGA-3928596", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3928596" } ] }, { "id": "R-GGA-3928604", "name": "SFKs phosphorylate VAV2,3", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XBZ6-1", "A0A8V0XFC9-1", "A0A8V0XHW1-1", "A0A8V0XPF0-1", "F1NJX6-1", "A0A8V0ZPH9-1", "A0A8V0ZXD3-1", "A0A8V0ZRU7-1", "A0A8V1A2E6-1", "A0A8V0YRJ8-1", "A0A8V0YUC4-1", "A0A8V0YYI3-1", "A0A8V0YZP9-1", "A0A8V0ZDU6-1", "A0A3Q2U639-1", "P09324-1" ], "evidence": [ { "id": "R-GGA-3928604", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3928604" } ] }, { "id": "R-GGA-3928607", "name": "p-EPHs bind VAV2,3", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XBZ6-1", "A0A8V0XFC9-1", "A0A8V0XHW1-1", "A0A8V0XPF0-1", "F1NJX6-1", "A0A8V0ZPH9-1", "A0A8V0ZXD3-1", "A0A8V0ZRU7-1", "A0A8V1A2E6-1", "A0A8V0YRJ8-1", "A0A8V0YUC4-1", "A0A8V0YYI3-1", "A0A8V0YZP9-1", "A0A8V0ZDU6-1", "A0A3Q2U639-1", "P09324-1" ], "evidence": [ { "id": "R-GGA-3928607", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3928607" } ] }, { "id": "R-GGA-3928627", "name": "EPHB phosphorylates TIAM1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XHW1-1", "A0A8V0ZRU7-1", "A0A8V1A2E6-1", "A0A8V0YUC4-1", "A0A8V0YZP9-1", "A0A8V0ZDU6-1", "A0A3Q2U639-1", "P09324-1" ], "evidence": [ { "id": "R-GGA-3928627", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3928627" } ] }, { "id": "R-GGA-3928628", "name": "VAV exchanges GTP for GDP on RAC1, activating it", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XBZ6-1", "A0A8V0XFC9-1", "A0A8V0XHW1-1", "A0A8V0XPF0-1", "F1NJX6-1", "A0A8V0ZPH9-1", "A0A8V0ZXD3-1", "A0A8V0ZRU7-1", "A0A8V1A2E6-1", "A0A8V0YRJ8-1", "A0A8V0YUC4-1", "A0A8V0YYI3-1", "A0A8V0YZP9-1", "A0A8V0Z8U4-1", "A0A8V0ZDU6-1", "A0A3Q2U639-1", "P09324-1" ], "evidence": [ { "id": "R-GGA-3928628", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3928628" } ] }, { "id": "R-GGA-3928642", "name": "TIAM1 exchanges GTP for GDP on RAC1, activating it", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XBZ6-1", "A0A8V0XFC9-1", "A0A8V0XHW1-1", "A0A8V0XPF0-1", "F1NJX6-1", "A0A8V0ZPH9-1", "A0A8V0ZXD3-1", "A0A8V0YRJ8-1", "A0A8V0YYI3-1", "A0A8V0Z8U4-1", "A0A8V0ZDU6-1", "A0A3Q2U639-1", "P09324-1" ], "evidence": [ { "id": "R-GGA-3928642", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3928642" } ] }, { "id": "R-GGA-3928645", "name": "EPHB:NMDAR binds TIAM1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XHW1-1", "A0A8V0ZRU7-1", "A0A8V1A2E6-1", "A0A8V0YUC4-1", "A0A8V0YZP9-1", "A0A8V0ZDU6-1", "A0A3Q2U639-1", "P09324-1" ], "evidence": [ { "id": "R-GGA-3928645", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3928645" } ] }, { "id": "R-GGA-3928651", "name": "NGEF exchanges GTP for GDP on RHOA", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XBZ6-1", "A0A8V0XFC9-1", "A0A8V0XHW1-1", "A0A8V0XPF0-1", "F1NJX6-1", "A0A8V0ZPH9-1", "A0A8V0ZXD3-1", "A0A8V0YRJ8-1", "A0A8V0YYI3-1", "A0A8V0ZDU6-1", "A0A3Q2U639-1", "P09324-1" ], "evidence": [ { "id": "R-GGA-3928651", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3928651" } ] }, { "id": "R-GGA-4093327", "name": "EPHA binds TIAM1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XBZ6-1", "A0A8V0XFC9-1", "A0A8V0XHW1-1", "A0A8V0XPF0-1", "F1NJX6-1", "A0A8V0ZPH9-1", "A0A8V0ZXD3-1", "A0A8V0YRJ8-1", "A0A8V0YYI3-1", "A0A8V0ZDU6-1", "A0A3Q2U639-1", "P09324-1" ], "evidence": [ { "id": "R-GGA-4093327", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4093327" } ] }, { "id": "R-GGA-4093336", "name": "p-TIAM1 exchanges GTP for GDP on RAC1, activating it", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XHW1-1", "A0A8V0ZRU7-1", "A0A8V1A2E6-1", "A0A8V0YUC4-1", "A0A8V0YZP9-1", "A0A8V0Z8U4-1", "A0A8V0ZDU6-1", "A0A3Q2U639-1", "P09324-1" ], "evidence": [ { "id": "R-GGA-4093336", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4093336" } ] }, { "id": "R-GGA-879917", "name": "CBL, GRB2, FYN and PI3K p85 subunit are constitutively associated", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XHW1-1", "A0A8V0ZY53-1", "F1NHX1-1", "A0A8V0YT43-1", "A0A3Q2U639-1", "F1N9Y5-1", "P09324-1" ], "evidence": [ { "id": "R-GGA-879917", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-879917" } ] }, { "id": "R-GGA-912627", "name": "CBL ubiquitinates PI3K", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XHW1-1", "A0A8V0ZY53-1", "F1NHX1-1", "A0A8V0YT43-1", "A0A3Q2U639-1", "F1N9Y5-1", "P09324-1" ], "evidence": [ { "id": "R-GGA-912627", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-912627" } ] } ], "reaction_participants": [ { "participant_id": "R-GGA-195066", "participant_name": "LOC107050724 [cytosol]", "crossref": [ { "id": "A0A8V0XJF3", "database": "UniProt", "url": "" }, { "id": "ENSGALG00010003064", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALP00010004390", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALT00010007334", "database": "ENSEMBL", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5PD64", "gene_name": "MAP2K3", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PD64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PD64" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A1D5PD64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PD64" } ] } ] }, { "uniprot_ac": "A0A3Q2U1T2", "gene_name": "BLK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2U1T2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U1T2" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A3Q2U1T2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U1T2" } ] } ] }, { "uniprot_ac": "A0A3Q2U639", "gene_name": "FYN", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2U639", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U639" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A3Q2U639", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U639" } ] } ] }, { "uniprot_ac": "A0A3Q2UKD3", "gene_name": "TEK", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2UKD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UKD3" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A3Q2UKD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UKD3" } ] } ] }, { "uniprot_ac": "A0A8V0X5W9", "gene_name": "TYK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X5W9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X5W9" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0X5W9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X5W9" } ] } ] }, { "uniprot_ac": "A0A8V0X6E7", "gene_name": "FES", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X6E7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X6E7" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0X6E7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X6E7" } ] } ] }, { "uniprot_ac": "A0A8V0XB17", "gene_name": "FGFR2", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XB17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XB17" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0XB17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XB17" } ] } ] }, { "uniprot_ac": "A0A8V0XBZ6", "gene_name": "EPHA7", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XBZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XBZ6" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0XBZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XBZ6" } ] } ] }, { "uniprot_ac": "A0A8V0XCY6", "gene_name": "TTK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XCY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCY6" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V0XCY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCY6" } ] } ] }, { "uniprot_ac": "A0A8V0XFC9", "gene_name": "EPHA5", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XFC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFC9" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0XFC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFC9" } ] } ] }, { "uniprot_ac": "A0A8V0XHW1", "gene_name": "LYN", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XHW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XHW1" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0XHW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XHW1" } ] } ] }, { "uniprot_ac": "A0A8V0XN86", "gene_name": "MUSK", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XN86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XN86" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0XN86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XN86" } ] } ] }, { "uniprot_ac": "A0A8V0XNF4", "gene_name": "EGFR", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XNF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNF4" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0XNF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNF4" } ] } ] }, { "uniprot_ac": "A0A8V0XPF0", "gene_name": "EPHA6", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XPF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XPF0" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0XPF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XPF0" } ] } ] }, { "uniprot_ac": "A0A8V0XQ80", "gene_name": "FLT3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQ80", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ80" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0XQ80", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ80" } ] } ] }, { "uniprot_ac": "A0A8V0XQG0", "gene_name": "FLT1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQG0" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0XQG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQG0" } ] } ] }, { "uniprot_ac": "A0A8V0XZ82", "gene_name": "PTK2B", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XZ82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XZ82" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0XZ82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XZ82" } ] } ] }, { "uniprot_ac": "A0A8V0Y7Y3", "gene_name": "ABL2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y7Y3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7Y3" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0Y7Y3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7Y3" } ] } ] }, { "uniprot_ac": "A0A8V0Y9A0", "gene_name": "PTK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y9A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9A0" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0Y9A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9A0" } ] } ] }, { "uniprot_ac": "A0A8V0YCV8", "gene_name": "NTRK2", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YCV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCV8" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0YCV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCV8" } ] } ] }, { "uniprot_ac": "A0A8V0YEV0", "gene_name": "WEE2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YEV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEV0" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0YEV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEV0" } ] } ] }, { "uniprot_ac": "A0A8V0YGR1", "gene_name": "RET", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YGR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGR1" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0YGR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGR1" } ] } ] }, { "uniprot_ac": "A0A8V0YIT6", "gene_name": "ERBB4", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YIT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIT6" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0YIT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIT6" } ] } ] }, { "uniprot_ac": "A0A8V0YIV6", "gene_name": "DYRK1A", "activity": [ { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] } ] }, { "uniprot_ac": "A0A8V0YJJ1", "gene_name": "ITK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YJJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJJ1" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": 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"L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YW12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YW12" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0YW12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YW12" } ] } ] }, { "uniprot_ac": "A0A8V0YWW2", "gene_name": "EPHA2", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YWW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YWW2" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0YWW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YWW2" } ] } ] }, { "uniprot_ac": "A0A8V0YXM5", "gene_name": "CSF1R", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] 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{ "id": "A0A8V0ZND5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZND5" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0ZND5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZND5" } ] } ] }, { "uniprot_ac": "A0A8V0ZP30", "gene_name": "LTK", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZP30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP30" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0ZP30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP30" } ] } ] }, { "uniprot_ac": "A0A8V0ZPH9", "gene_name": "EPHA1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZPH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPH9" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0ZPH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPH9" } ] } ] }, { "uniprot_ac": "A0A8V0ZRU7", "gene_name": "EPHB6", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZRU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRU7" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0ZRU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRU7" } ] } ] }, { "uniprot_ac": "A0A8V0ZSN8", "gene_name": "JAK1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZSN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSN8" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0ZSN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSN8" } ] } ] }, { "uniprot_ac": "A0A8V0ZWV8", "gene_name": "TIE1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZWV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWV8" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0ZWV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWV8" } ] } ] }, { "uniprot_ac": "A0A8V0ZXD3", "gene_name": "EPHA4", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZXD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXD3" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0ZXD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXD3" } ] } ] }, { "uniprot_ac": "A0A8V0ZXS7", "gene_name": "ERBB2", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZXS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXS7" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0ZXS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXS7" } ] } ] }, { "uniprot_ac": "A0A8V0ZY53", "gene_name": "CBL", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZY53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZY53" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZY53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZY53" } ] } ] }, { "uniprot_ac": "A0A8V1A069", "gene_name": "TESK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A069", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A069" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1A069", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A069" } ] } ] }, { "uniprot_ac": "A0A8V1A2E6", "gene_name": "EPHB1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A2E6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2E6" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V1A2E6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2E6" } ] } ] }, { "uniprot_ac": "A0A8V1A3N1", "gene_name": "MST1R", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A3N1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3N1" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V1A3N1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3N1" } ] } ] }, { "uniprot_ac": "A0A8V1A7E0", "gene_name": "DYRK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1A7E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E0" } ] } ] }, { "uniprot_ac": "A0A8V1A7N1", "gene_name": "ERBB3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7N1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7N1" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V1A7N1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7N1" } ] } ] }, { "uniprot_ac": "A0A8V1A9R2", "gene_name": "JAK3", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A9R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9R2" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V1A9R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9R2" } ] } ] }, { "uniprot_ac": "A0A8V1ABP4", "gene_name": "DSTYK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP4" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1ABP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP4" } ] } ] }, { "uniprot_ac": "A0A8V1ACF7", "gene_name": "ABL1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF7" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V1ACF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF7" } ] } ] }, { "uniprot_ac": "A0A8V1ADF0", "gene_name": "MAP2K2", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF0" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V1ADF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF0" } ] } ] }, { "uniprot_ac": "A0A8V1AEL3", "gene_name": "ZAP70", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AEL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEL3" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V1AEL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEL3" } ] } ] }, { "uniprot_ac": "A0A8V1AFM7", "gene_name": "INSR", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AFM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFM7" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V1AFM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFM7" } ] } ] }, { "uniprot_ac": "A0A8V1AKW4", "gene_name": "MAP2K4", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AKW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKW4" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V1AKW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKW4" } ] } ] }, { "uniprot_ac": "A0A8V1AMK9", "gene_name": "BAZ1B", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AMK9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK9" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V1AMK9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK9" } ] } ] }, { "uniprot_ac": "E1BTE1", "gene_name": "WEE2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BTE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BTE1" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "E1BTE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BTE1" } ] } ] }, { "uniprot_ac": "E1BTT3", "gene_name": "BMX", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BTT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BTT3" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "E1BTT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BTT3" } ] } ] }, { "uniprot_ac": "E1BX69", "gene_name": "EIF2AK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BX69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BX69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BX69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BX69" } ] } ] }, { "uniprot_ac": "E1C2C8", "gene_name": "MATK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C2C8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2C8" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "E1C2C8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2C8" } ] } ] }, { "uniprot_ac": "E1C7Z1", "gene_name": "FER", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C7Z1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C7Z1" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "E1C7Z1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C7Z1" } ] } ] }, { "uniprot_ac": "F1N996", "gene_name": "PTK6", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N996", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N996" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F1N996", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N996" } ] } ] }, { "uniprot_ac": "F1N9Y5", "gene_name": "SYK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N9Y5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N9Y5" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F1N9Y5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N9Y5" } ] } ] }, { "uniprot_ac": "F1NCL8", "gene_name": "FGFR4", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NCL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCL8" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1NCL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCL8" } ] } ] }, { "uniprot_ac": "F1NHX1", "gene_name": "PIK3CD", "activity": [ { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "F1NHX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NHX1" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "F1NHX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NHX1" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "F1NHX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NHX1" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "F1NHX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NHX1" } ] } ] }, { "uniprot_ac": "F1NJX6", "gene_name": "EPHA3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NJX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJX6" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1NJX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJX6" } ] } ] }, { "uniprot_ac": "F1NLR7", "gene_name": "CLK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NLR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLR7" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "F1NLR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLR7" } ] } ] }, { "uniprot_ac": "F1NQL9", "gene_name": "ROS1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NQL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NQL9" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1NQL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NQL9" } ] } ] }, { "uniprot_ac": "F1NUX4", "gene_name": "MTOR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NUX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NUX4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NUX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NUX4" } ] } ] }, { "uniprot_ac": "F1NVF2", "gene_name": "MAP2K6", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NVF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVF2" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "F1NVF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVF2" } ] } ] }, { "uniprot_ac": "F1NW21", "gene_name": "KDR", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NW21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NW21" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1NW21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NW21" } ] } ] }, { "uniprot_ac": "F1NZY8", "gene_name": "TEC", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NZY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NZY8" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F1NZY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NZY8" } ] } ] }, { "uniprot_ac": "H9KZZ1", "gene_name": "NTRK1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "H9KZZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H9KZZ1" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "H9KZZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H9KZZ1" } ] } ] }, { "uniprot_ac": "H9KZZ2", "gene_name": "INSRR", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "H9KZZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H9KZZ2" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "H9KZZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H9KZZ2" } ] } ] }, { "uniprot_ac": "O42422", "gene_name": "EPHA7", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "O42422", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O42422" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "O42422", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O42422" } ] } ] }, { "uniprot_ac": "P00523", "gene_name": "SRC", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "P00523", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00523" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "P00523", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00523" } ] } ] }, { "uniprot_ac": "P08941", "gene_name": "ROS1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "P08941", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P08941" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "P08941", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P08941" } ] } ] }, { "uniprot_ac": "P09324", "gene_name": "YES1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "P09324", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P09324" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "P09324", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P09324" } ] } ] }, { "uniprot_ac": "P13387", "gene_name": "EGFR", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "P13387", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13387" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "P13387", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13387" } ] } ] }, { "uniprot_ac": "P18460", "gene_name": "FGFR3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "P18460", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18460" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "P18460", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18460" } ] } ] }, { "uniprot_ac": "P18461", "gene_name": "FGFR2", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "P18461", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18461" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "P18461", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18461" } ] } ] }, { "uniprot_ac": "P21804", "gene_name": "FGFR1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "P21804", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21804" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "P21804", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21804" } ] } ] }, { "uniprot_ac": "P28693", "gene_name": "EPHB2", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "P28693", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P28693" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "P28693", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P28693" } ] } ] }, { "uniprot_ac": "P29318", "gene_name": "EPHA3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "P29318", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P29318" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "P29318", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P29318" } ] } ] }, { "uniprot_ac": "P41239", "gene_name": "CSK", "activity": [ { "ec_number": "2.7.10.4", "activity": "ATP + [a protein]-(L-tyrosine) = ADP + [a protein]-(L-tyrosine)-phosphate. The optimal peptide substrate contains the sequence (relative to the phosphorylated tyrosine): Glu-Glu-Asp/Glu-Ile-Tyr-Phe-Phe-Phe-Phe. Physiological substrates are C-terminal tail of Src-family protein kinases.", "evidence": [ { "id": "P41239", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P41239" } ] }, { "ec_number": "2.7.10.4", "activity": "", "evidence": [ { "id": "P41239", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P41239" } ] } ] }, { "uniprot_ac": "P42683", "gene_name": "LCK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "P42683", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P42683" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "P42683", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P42683" } ] } ] }, { "uniprot_ac": "P54755", "gene_name": "EPHA5", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "P54755", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P54755" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "P54755", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P54755" } ] } ] }, { "uniprot_ac": "Q00944", "gene_name": "PTK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q00944", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q00944" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "Q00944", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q00944" } ] } ] }, { "uniprot_ac": "Q02977", "gene_name": "YRK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q02977", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q02977" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "Q02977", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q02977" } ] } ] }, { "uniprot_ac": "Q05876", "gene_name": "FYN", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q05876", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q05876" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "Q05876", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q05876" } ] } ] }, { "uniprot_ac": "Q07494", "gene_name": "EPHB1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q07494", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q07494" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "Q07494", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q07494" } ] } ] }, { "uniprot_ac": "Q07496", "gene_name": "EPHA4", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q07496", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q07496" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "Q07496", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q07496" } ] } ] }, { "uniprot_ac": "Q07497", "gene_name": "EPHB5", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q07497", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q07497" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "Q07497", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q07497" } ] } ] }, { "uniprot_ac": "Q07498", "gene_name": "EPHB3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q07498", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q07498" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "Q07498", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q07498" } ] } ] }, { "uniprot_ac": "Q08156", "gene_name": "KIT", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q08156", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08156" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "Q08156", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08156" } ] } ] }, { "uniprot_ac": "Q5ZIU3", "gene_name": "DYRK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5ZIU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZIU3" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q5ZIU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZIU3" } ] } ] }, { "uniprot_ac": "Q6XUX0", "gene_name": "DSTYK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q6XUX0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6XUX0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q6XUX0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6XUX0" } ] } ] }, { "uniprot_ac": "Q75R65", "gene_name": "JAK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q75R65", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q75R65" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "Q75R65", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q75R65" } ] } ] }, { "uniprot_ac": "Q8AXY6", "gene_name": "MUSK", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q8AXY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8AXY6" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "Q8AXY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8AXY6" } ] } ] }, { "uniprot_ac": "Q8JH64", "gene_name": "BTK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q8JH64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8JH64" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "Q8JH64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8JH64" } ] } ] }, { "uniprot_ac": "Q8QHL3", "gene_name": "FLT1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q8QHL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8QHL3" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "Q8QHL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8QHL3" } ] } ] }, { "uniprot_ac": "Q90687", "gene_name": "PTPN11", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q90687", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q90687" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q90687", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q90687" } ] } ] }, { "uniprot_ac": "Q90891", "gene_name": "MAP2K2", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q90891", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q90891" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "Q90891", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q90891" } ] } ] }, { "uniprot_ac": "Q91009", "gene_name": "NTRK1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q91009", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q91009" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "Q91009", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q91009" } ] } ] }, { "uniprot_ac": "Q91044", "gene_name": "NTRK3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q91044", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q91044" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "Q91044", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q91044" } ] } ] }, { "uniprot_ac": "Q91987", "gene_name": "NTRK2", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q91987", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q91987" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "Q91987", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q91987" } ] } ] }, { "uniprot_ac": "Q98949", "gene_name": "TYRO3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = 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alkenal/one oxidoreductase", "type": "synonym", "evidence": [ { "id": "A0A8V0XY15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XY15/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0XY15", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XY15" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PTGR1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XY15", "locus": { "chromosome": "Z", "start_pos": 67197032, "end_pos": 67179315, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010006355", "url": "https://www.ensembl.org/id/ENSGALG00010006355" } ] } } ], "crossref": [ { "id": "A0A8V0XY15", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0XY15", "database": 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"https://www.ebi.ac.uk/interpro/entry/IPR041694", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045010", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045010", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XL48", "url": "https://www.orthodb.org/?gene=A0A8V0XL48", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XV80", "url": "https://www.orthodb.org/?gene=A0A8V0XV80", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XV85", "url": "https://www.orthodb.org/?gene=A0A8V0XV85", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XY15", "url": "https://www.orthodb.org/?gene=A0A8V0XY15", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR43205", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43205", "database": "PANTHER", "categories": [ "Protein Classification" ] 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"categories": [ "Protein" ] }, { "id": "A0A8V0XV85-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XV85-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XY15", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XY15", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XY15-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XY15-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPIGLFKLRVVPVAFFDLWNLCFTAVTQEFALFFVAELLLESVFLSVDPYMRPYSKRDMKEGDVMIGTQVARIVESKNPAFAVGTFVVANRGWRTHFISDGKDLNLLPASWPESLPKSLALGTVGMPGLTAYVGLFEICKMKPGETVLVNAAAGAVGSVVGQLAKIGGCKVVGCAGSDSKVAYLKNIGFDEAFNYKTVASLDEALRKASPDGYDCFFDNVGGEFASIAINHMKKFGRIAVCGAISQYNDSVPQKGPYIQIPMIFNELSMKGFIVSSWHNHREEGVKALLKWVLEGKLKYHEQVTERFENMPAAFIGMLKGENLGKAVVKV", "length": 330, "header": "tr|A0A8V0XY15-1|A0A8V0XY15_CHICK Isoform 1 of Prostaglandin reductase 1 OS=Gallus gallus OX=9031 GN=PTGR1 PE=1 SV=1 CANONICAL=A0A8V0XY15-1" }, "isoforms": [ { "isoform_ac": "A0A8V0XL48-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XY15/entry#A0A8V0XL48-1", "sequence": { "sequence": "MVTAKVWVLKKHFEGFPKPSDFEMKQVALANLKDGELLLESVFLSVDPYMRPYSKRDMKEGDVMIGTQVASRIVESKNPAFAVGTFVVANRGWRTHFISDGKDLNLLPASWPESLPKSLALGTVGMPGLTAYVGLFEICKMKPGETVLVNAAAGAVGSVVGQLAKIGGCKVVGCAGSDSKVAYLKNIGFDEAFNYKTVASLDEALRKASPDGYDCFFDNVGGEFASIAINHMKKFGRIAVCGAISQYNDSVPQKGPYIQIPMIFNELSMKGFIVSSWHNHREEGVKALLKWVLEGKLKYHEQVTERFENMPAAFIGMLKGENLGKAVVKV", "length": 330, "header": "tr|A0A8V0XL48-1|A0A8V0XY15_CHICK Computationally mapped isoform of Prostaglandin reductase 1 OS=Gallus gallus OX=9031 GN=PTGR1 PE=1 SV=1 CANONICAL=A0A8V0XY15-1" }, "locus": { "chromosome": "Z", "start_pos": 67196114, "end_pos": 67188476, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010015180.1", "url": "https://www.ensembl.org/id/ENSGALT00010015180.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010008917.1", "url": "https://www.ensembl.org/id/ENSGALP00010008917.1" } ] } }, { "isoform_ac": "A0A8V0XV80-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XY15/entry#A0A8V0XV80-1", "sequence": { "sequence": "MNEPRVLASHGHLHHLHHAVLNLIPLFILHKIYFSLGELLLESVFLSVDPYMRPYSKRDMKEGDVMIGTQVARIVESKNPAFAVGTFVVANRGWRTHFISDGKDLNLLPASWPESLPKSLALGTVGMPGLTAYVGLFEICKMKPGETVLVNAAAGAVGSVVGQLAKIGGCKVVGCAGSDSKVAYLKNIGFDEAFNYKTVASLDEALRKASPDGYDCFFDNVGGEFASIAINHMKKFGRIAVCGAISQYNDSVPQKGPYIQIPMIFNELSMKGFIVSSWHNHREEGVKALLKWVLEGKLKYHEQVTERFENMPAAFIGMLKGENLGKAVVKV", "length": 331, "header": "tr|A0A8V0XV80-1|A0A8V0XV80_CHICK Computationally mapped isoform of Prostaglandin reductase 1 OS=Gallus gallus OX=9031 GN=PTGR1 PE=1 SV=1 CANONICAL=A0A8V0XY15-1" }, "locus": { "chromosome": "Z", "start_pos": 67196114, "end_pos": 67189442, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010015164.1", "url": "https://www.ensembl.org/id/ENSGALT00010015164.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010008910.1", "url": "https://www.ensembl.org/id/ENSGALP00010008910.1" } ] } }, { "isoform_ac": "A0A8V0XV85-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XY15/entry#A0A8V0XV85-1", "sequence": { "sequence": "MSAYQRWVASDVVIRSSGCLFCSPLTPYTALASSLAPFSISLCCSFCRMVTAKVWVLKKHFEGFPKPSDFEMKQVALANLKDGELLLESVFLSVDPYMRPYSKRDMKEGDVMIGTQVARIVESKNPAFAVGTFVVANRGWRTHFISDGKDLNLLPASWPESLPKSLALGTVGMPGLTAYVGLFEICKMKPGETVLVNAAAGAVGSVVGQLAKIGGCKVVGCAGSDSKVAYLKNIGFDEAFNYKTVASLDEALRKASPDGYDCFFDNVGGEFASIAINHMKKFGRIAVCGAISQYNDSVPQKGPYIQIPMIFNELSMKGFIVSSWHNHREEGVKALLKWVLEGKLKYHEQVTERFENMPAAFIGMLKGENLGKAVVKV", "length": 377, "header": "tr|A0A8V0XV85-1|A0A8V0XV85_CHICK Computationally mapped isoform of Prostaglandin reductase 1 OS=Gallus gallus OX=9031 GN=PTGR1 PE=1 SV=1 CANONICAL=A0A8V0XY15-1" }, "locus": { "chromosome": "Z", "start_pos": 67196114, "end_pos": 67188332, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010015176.1", "url": "https://www.ensembl.org/id/ENSGALT00010015176.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010008915.1", "url": "https://www.ensembl.org/id/ENSGALP00010008915.1" } ] } }, { "isoform_ac": "A0A8V0XY15-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XY15/entry#A0A8V0XY15-1", "sequence": { "sequence": "MPIGLFKLRVVPVAFFDLWNLCFTAVTQEFALFFVAELLLESVFLSVDPYMRPYSKRDMKEGDVMIGTQVARIVESKNPAFAVGTFVVANRGWRTHFISDGKDLNLLPASWPESLPKSLALGTVGMPGLTAYVGLFEICKMKPGETVLVNAAAGAVGSVVGQLAKIGGCKVVGCAGSDSKVAYLKNIGFDEAFNYKTVASLDEALRKASPDGYDCFFDNVGGEFASIAINHMKKFGRIAVCGAISQYNDSVPQKGPYIQIPMIFNELSMKGFIVSSWHNHREEGVKALLKWVLEGKLKYHEQVTERFENMPAAFIGMLKGENLGKAVVKV", "length": 330, "header": "tr|A0A8V0XY15-1|A0A8V0XY15_CHICK Isoform 1 of Prostaglandin reductase 1 OS=Gallus gallus OX=9031 GN=PTGR1 PE=1 SV=1 CANONICAL=A0A8V0XY15-1" }, "locus": { "chromosome": "Z", "start_pos": 67196114, "end_pos": 67190210, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010015170.1", "url": "https://www.ensembl.org/id/ENSGALT00010015170.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010008913.1", "url": "https://www.ensembl.org/id/ENSGALP00010008913.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "2-alkenal reductase [NAD(P)H] activity", "id": "GO:0032440", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032440", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0XY15", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XY15" } ], "pmid": "" }, { "name": "15-oxoprostaglandin 13-reductase [NAD(P)+] activity", "id": "GO:0047522", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047522", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0XY15", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XY15" } ], "pmid": "" }, { "name": "2-alkenal reductase (NADPH) activity", "id": "GO:0035798", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035798", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0XY15", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XY15" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0XY15", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XY15" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "prostaglandin metabolic process", "id": "GO:0006693", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006693", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0XY15", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XY15" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 248, "end_pos": 250, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "13737", "name": "", "equation": "an n-alkanal + NADP(+) = an alk-2-enal + NADPH + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XY15-1" ], "evidence": [ { "id": "13737", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/13737" } ] }, { "id": "50584", "name": "", "equation": "13,14-dihydro-15-oxo-prostaglandin E1 + NADP(+) = 15-oxoprostaglandin E1 + NADPH + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0Z902-1", "A0A8V0XY15-1" ], "evidence": [ { "id": "50584", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/50584" } ] }, { "id": "50588", "name": "", "equation": "13,14-dihydro-15-oxo-PGF2alpha + NADP(+) = 15-oxoprostaglandin F2alpha + NADPH + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0Z902-1", "A0A8V0XY15-1" ], "evidence": [ { "id": "50588", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/50588" } ] }, { "id": "50592", "name": "", "equation": "13,14-dihydro-15-oxo-prostaglandin F1alpha + NADP(+) = 15-oxoprostaglandin F1alpha + NADPH + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0Z902-1", "A0A8V0XY15-1" ], "evidence": [ { "id": "50592", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/50592" } ] }, { "id": "50608", "name": "", "equation": "leukotriene B4 + NADP(+) = 12-oxo-leukotriene B4 + NADPH + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XY15-1" ], "evidence": [ { "id": "50608", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/50608" } ] }, { "id": "50612", "name": "", "equation": "decanal + NADP(+) = (2E)-decenal + NADPH + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XY15-1" ], "evidence": [ { "id": "50612", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/50612" } ] }, { "id": "50616", "name": "", "equation": "nonan-2-one + NADP(+) = (3E)-nonen-2-one + NADPH + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XY15-1" ], "evidence": [ { "id": "50616", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/50616" } ] }, { "id": "50776", "name": "", "equation": "hexanal + NADP(+) = (E)-hex-2-enal + NADPH + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XY15-1" ], "evidence": [ { "id": "50776", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/50776" } ] }, { "id": "50780", "name": "", "equation": "octanal + NADP(+) = (2E)-octenal + NADPH + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XY15-1" ], "evidence": [ { "id": "50780", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/50780" } ] }, { "id": "50784", "name": "", "equation": "dodecanal + NADP(+) = (2E)-dodecenal + NADPH + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XY15-1" ], "evidence": [ { "id": "50784", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/50784" } ] }, { "id": "50788", "name": "", "equation": "pentan-2-one + NADP(+) = (E)-pent-3-en-2-one + NADPH + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XY15-1" ], "evidence": [ { "id": "50788", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/50788" } ] }, { "id": "51204", "name": "", "equation": "6-trans-leukotriene B4 + NADP(+) = 12-oxo-(5S)-hydroxy-(6E,8E,10E,14Z)-eicosatetraenoate + NADPH + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XY15-1" ], "evidence": [ { "id": "51204", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/51204" } ] }, { "id": "51208", "name": "", "equation": "20-hydroxy-leukotriene B4 + NADP(+) = 12-oxo-20-hydroxy-leukotriene B4 + NADPH + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XY15-1" ], "evidence": [ { "id": "51208", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/51208" } ] }, { "id": "51212", "name": "", "equation": "(5S,12S)-dihydroxy-(6E,10E,12E,14Z)-eicosatetraenoate + NADP(+) = 12-oxo-(5S)-hydroxy-(6E,8E,10E,14Z)-eicosatetraenoate + NADPH + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XY15-1" ], "evidence": [ { "id": "51212", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/51212" } ] }, { "id": "64736", "name": "", "equation": "4-hydroxynonanal + NADP(+) = (E)-4-hydroxynon-2-enal + NADPH + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XY15-1" ], "evidence": [ { "id": "64736", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/64736" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0XY15", "gene_name": "PTGR1", "activity": [ { "ec_number": "1.3.1.74", "activity": "an n-alkanal + NADP(+) = an alk-2-enal + NADPH + H(+).", "evidence": [ { "id": "A0A8V0XY15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XY15" } ] }, { "ec_number": "1.3.1.48", "activity": "13,14-dihydro-15-oxo-prostaglandin E2 + NAD(+) = 15-oxoprostaglandin E2 + NADH + H(+).", "evidence": [ { "id": "A0A8V0XY15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XY15" } ] }, { "ec_number": 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"NP_990342", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990342" }, { "id": "O73888", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O73888" } ] }, { "name": "H-PGDS", "type": "synonym", "evidence": [ { "id": "NP_990342", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990342" } ] }, { "name": "HPGDS", "type": "synonym", "evidence": [ { "id": "NP_990342", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990342" } ] }, { "name": "PGDS", "type": "synonym", "evidence": [ { "id": "NP_990342", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990342" }, { "id": "O73888", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O73888" } ] }, { "name": "PTGDS2", "type": "synonym", "evidence": [ { "id": "NP_990342", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990342" }, { "id": "O73888", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O73888" } ] } ], "protein_names": [ { "name": "Hematopoietic prostaglandin D synthase", "type": "recommended", "evidence": [ { "id": "O73888", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O73888/entry#names_and_taxonomy" } ] }, { "name": "2.5.1.18", "type": "synonym", "evidence": [ { "id": "O73888", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O73888/entry#names_and_taxonomy" } ] }, { "name": "5.3.99.2", "type": "synonym", "evidence": [ { "id": "O73888", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O73888/entry#names_and_taxonomy" } ] }, { "name": "GST class-sigma", "type": "synonym", "evidence": [ { "id": "NP_990342", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990342" }, { "id": "O73888", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O73888/entry#names_and_taxonomy" } ] }, { "name": "Glutathione S-transferase", "type": "synonym", "evidence": [ { "id": "O73888", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O73888/entry#names_and_taxonomy" } ] }, { "name": "Glutathione-dependent PGD synthase", "type": "synonym", "evidence": [ { "id": "O73888", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O73888/entry#names_and_taxonomy" } ] }, { "name": "Glutathione-requiring prostaglandin D synthase", "type": "synonym", "evidence": [ { "id": "O73888", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O73888/entry#names_and_taxonomy" } ] }, { "name": "H-PGDS", "type": "synonym", "evidence": [ { "id": "O73888", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O73888/entry#names_and_taxonomy" } ] }, { "name": "Prostaglandin-H2 D-isomerase", "type": "synonym", "evidence": [ { "id": "O73888", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O73888/entry#names_and_taxonomy" } ] }, { "name": "glutathione S-transferase", "type": "synonym", "evidence": [ { "id": "NP_990342", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990342" } ] }, { "name": "glutathione-dependent PGD synthase", "type": "synonym", "evidence": [ { "id": "NP_990342", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990342" } ] }, { "name": "glutathione-dependent PGD synthetase", "type": "synonym", "evidence": [ { "id": "NP_990342", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990342" } ] }, { "name": "glutathione-requiring prostaglandin D synthase", "type": "synonym", "evidence": [ { "id": "NP_990342", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990342" } ] }, { "name": "hematopoietic prostaglandin D synthase", "type": "synonym", "evidence": [ { "id": "NP_990342", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990342" } ] }, { "name": "prostaglandin-D synthase", "type": "synonym", "evidence": [ { "id": "NP_990342", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990342" } ] }, { "name": "prostaglandin-H2 D-isomerase", "type": "synonym", "evidence": [ { "id": "NP_990342", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990342" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: HAEK01090482.1, HAEK01117890.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992428, SAMEA103992484 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000073.1.", "evidence": [ { "database": "RefSeq", "id": "NP_990342", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990342" } ] }, { "annotation": "Bifunctional enzyme which catalyzes both the conversion of PGH2 to PGD2, a prostaglandin involved in smooth muscle contraction/relaxation and a potent inhibitor of platelet aggregation, and the conjugation of glutathione with a wide range of aryl halides, organic isothiocyanates and alpha,beta-unsaturated carbonyls. Also exhibits low glutathione-peroxidase activity towards cumene hydroperoxide and t-butyl hydroperoxide.", "evidence": [ { "database": "UniProtKB", "id": "O73888", "url": "https://www.uniprot.org/uniprotkb/O73888#function" }, { "database": "PubMed", "id": "9657971", "url": "https://glygen.org/publication/PubMed/9657971" } ] }, { "annotation": "PGDS induces LH beta transcription and subsequent translation via the Peroxisome Proliferator-Activated Receptor (PPAR) signaling pathway.", "evidence": [ { "database": "RefSeq", "id": "NP_990342", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990342" }, { "database": "PubMed", "id": "19954828", "url": "https://glygen.org/publication/PubMed/19954828" } ] }, { "annotation": "The expression of both H-PGDS and WNT2, which are involved in the prostaglandin D2 and WNT signaling pathways, respectively, was low in the testis of low sperm motility phenotype roosters.", "evidence": [ { "database": "RefSeq", "id": "NP_990342", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990342" }, { "database": "PubMed", "id": "31065698", "url": "https://glygen.org/publication/PubMed/31065698" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "O73888", "url": "https://www.uniprot.org/uniprotkb/O73888" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "HPGDS", "url": "https://www.uniprot.org/uniprotkb/O73888", "locus": { "chromosome": "4", "start_pos": 36743634, "end_pos": 36772199, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010005518", "url": "https://www.ensembl.org/id/ENSGALG00010005518" } ] } } ], "crossref": [ { "id": "O73888", "url": "https://alphafold.ebi.ac.uk/entry/O73888", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000010402", "url": 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[ "Protein Classification" ] }, { "id": "IPR010987", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010987", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036249", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036249", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036282", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036282", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040079", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040079", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050213", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050213", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:395863", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395863", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "EVRPYFM", "url": "https://omabrowser.org/oma/group/EVRPYFM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XM47", "url": "https://www.orthodb.org/?gene=A0A8V0XM47", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XUQ9", "url": "https://www.orthodb.org/?gene=A0A8V0XUQ9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "O73888", "url": "https://www.orthodb.org/?gene=O73888", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11571", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11571", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11571:SF224", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11571:SF224", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02798", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02798", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14497", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14497", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:O73888", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:O73888", "database": "PRO", "categories": [ "Protein" ] }, { "id": "R-GGA-156590", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-156590", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-2162123", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2162123", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_990342", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990342", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "10600", "url": "https://www.rhea-db.org/rhea/10600", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "16437", "url": "https://www.rhea-db.org/rhea/16437", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "51232", "url": "https://www.rhea-db.org/rhea/51232", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0XM47", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XM47", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XM47-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XM47-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XUQ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XUQ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XUQ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XUQ9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "O73888", "url": "https://www.uniprot.org/uniprotkb/O73888", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "O73888-1", "url": "https://www.uniprot.org/uniprotkb/O73888-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPNYKLTYFNLRGRAEICRYLFAYAGIKYEDHRLEGADWPKIKPTIPFGKVPILEVDGVIIHQSLAIARYLARESGLAGQTPVEQALADAIVDTIDDFMMLFPWAEKNQDVKEKAFNDILTNKAPELLKDLDTFLGDKKWFVGKSVTWADFYWDVCSTTLLSYKADLADKYPRLLALRDRVEALPAIAAWIQKRPKTAI", "length": 199, "header": "sp|O73888-1|HPGDS_CHICK Isoform 1 of Hematopoietic prostaglandin D synthase OS=Gallus gallus OX=9031 GN=HPGDS PE=1 SV=3 CANONICAL=O73888-1" }, "isoforms": [ { "isoform_ac": "A0A8V0XM47-1", "url": "https://www.uniprot.org/uniprotkb/O73888/entry#A0A8V0XM47-1", "sequence": { "sequence": "MPNYKLTYFNLRGRAEICRYLFAYAGIKYEDHRLEGADWPKIKPTIPFGKVPILEVDGVIIHQSLAIARYLARESGLAGQTPVEQALADAIVDTIDDFMMLFPWAEKNQDVKKAFNDILTNKAPELLKDLDTFLGDKKWFVGKSVTWADFYWDVCSTTLLSYKADLADKYPRLLALRDRVEALPAIAAWIQKRPKTAI", "length": 198, "header": "tr|A0A8V0XM47-1|HPGDS_CHICK Computationally mapped isoform of Hematopoietic prostaglandin D synthase OS=Gallus gallus OX=9031 GN=HPGDS PE=1 SV=1 CANONICAL=O73888-1" }, "locus": { "chromosome": "4", "start_pos": 36761781, "end_pos": 36747062, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010013202.1", "url": "https://www.ensembl.org/id/ENSGALT00010013202.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010007764.1", "url": "https://www.ensembl.org/id/ENSGALP00010007764.1" } ] } }, { "isoform_ac": "A0A8V0XUQ9-1", "url": "https://www.uniprot.org/uniprotkb/O73888/entry#A0A8V0XUQ9-1", "sequence": { "sequence": "MHHKYQPQTSFLHFQGPIMPNYKLTYFNLRGRAEICRYLFAYAGIKYEDHRLEGADWPKIKPTIPFGKVPILEVDGVIIHQSLAIARYLARESGLAGQTPVEQALADAIVDTIDDFMMLFPWAEKNQDVKEKAFNDILTNKAPELLKDLDTFLGDKKWFVGKSVTWADFYWDVCSTTLLSYKADLADKYPRLLALRDRVEALPAIAAWIQKRPKTAI", "length": 217, "header": "tr|A0A8V0XUQ9-1|HPGDS_CHICK Computationally mapped isoform of Hematopoietic prostaglandin D synthase OS=Gallus gallus OX=9031 GN=HPGDS PE=1 SV=1 CANONICAL=O73888-1" }, "locus": { "chromosome": "4", "start_pos": 36764940, "end_pos": 36747062, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010013199.1", "url": "https://www.ensembl.org/id/ENSGALT00010013199.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010007761.1", "url": "https://www.ensembl.org/id/ENSGALP00010007761.1" } ] } }, { "isoform_ac": "O73888-1", "url": "https://www.uniprot.org/uniprotkb/O73888/entry#O73888-1", "sequence": { "sequence": "MPNYKLTYFNLRGRAEICRYLFAYAGIKYEDHRLEGADWPKIKPTIPFGKVPILEVDGVIIHQSLAIARYLARESGLAGQTPVEQALADAIVDTIDDFMMLFPWAEKNQDVKEKAFNDILTNKAPELLKDLDTFLGDKKWFVGKSVTWADFYWDVCSTTLLSYKADLADKYPRLLALRDRVEALPAIAAWIQKRPKTAI", "length": 199, "header": "sp|O73888-1|HPGDS_CHICK Isoform 1 of Hematopoietic prostaglandin D synthase OS=Gallus gallus OX=9031 GN=HPGDS PE=1 SV=3 CANONICAL=O73888-1" }, "locus": { "chromosome": "4", "start_pos": 36761781, "end_pos": 36747062, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010013205.1", "url": "https://www.ensembl.org/id/ENSGALT00010013205.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010007767.1", "url": "https://www.ensembl.org/id/ENSGALP00010007767.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "Identification of estrogen-responsive genes in chick liver.", "journal": "Cell Tissue Res.", "date": "2001", "authors": "Zhu Y, Wang M, Lin H, Li Z, Luo J", "evidence": [ { "database": "UniProtKB", "id": "O73888", "url": "https://www.uniprot.org/uniprotkb/O73888" } ], "reference": [ { "type": "PubMed", "id": "11572089", "url": "https://glygen.org/publication/PubMed/11572089" } ] }, { "title": "Prostaglandin-D synthetase induces transcription of the LH beta subunit in the primary culture of chicken anterior pituitary cells via the PPAR signaling pathway.", "journal": "Theriogenology", "date": "2010-02", "authors": "Chen L-R, Lee S-C, Lin Y-P, Hsieh Y-L, Chen Y-L, Yang J-R, Liou J-F, Chen C-F, Lee Y-P, Shiue Y-L", "evidence": [ { "database": "RefSeq", "id": "NP_990342", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990342" } ], "reference": [ { "type": "PubMed", "id": "19954828", "url": "https://glygen.org/publication/PubMed/19954828" } ] }, { "title": "Differences in semen quality, testicular histomorphology, fertility, reproductive hormone levels, and expression of candidate genes according to sperm motility in Beijing-You chickens.", "journal": "Poultry science", "date": "2019-09-01", "authors": "Sun Yanyan, Xue Fuguang, Li Yunlei, Fu Li, Bai Hao, Ma Hui, Xu Songshan, Chen Jilan", "evidence": [ { "database": "RefSeq", "id": "NP_990342", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990342" } ], "reference": [ { "type": "PubMed", "id": "31065698", "url": "https://glygen.org/publication/PubMed/31065698" } ] }, { "title": "Sequence, catalytic properties and expression of chicken glutathione-dependent prostaglandin D2 synthase, a novel class Sigma glutathione S-transferase.", "journal": "The Biochemical journal", "date": "1998-07-15", "authors": "Thomson A M, Meyer D J, Hayes J D", "evidence": [ { "database": "UniProtKB", "id": "O73888", "url": "https://www.uniprot.org/uniprotkb/O73888" } ], "reference": [ { "type": "PubMed", "id": "9657971", "url": "https://glygen.org/publication/PubMed/9657971" } ] } ], "pathway": [ { "id": "gga:395863", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395863", "resource": "KEGG Pathway" }, { "id": "R-GGA-156590", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-156590", "resource": "Reactome", "description": "Glutathione conjugation" }, { "id": "R-GGA-2162123", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2162123", "resource": "Reactome", "description": "Synthesis of Prostaglandins (PG) and Thromboxanes (TX)" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "prostaglandin-D synthase activity", "id": "GO:0004667", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004667", "evidence": [ { "database": "UniProtKB", "id": "O73888", "url": "https://www.uniprot.org/uniprotkb/O73888" } ], "pmid": "" }, { "name": "glutathione transferase activity", "id": "GO:0004364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004364", "evidence": [ { "database": "UniProtKB", "id": "O73888", "url": "https://www.uniprot.org/uniprotkb/O73888" } ], "pmid": "" }, { "name": "magnesium ion binding", "id": "GO:0000287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000287", "evidence": [ { "database": "UniProtKB", "id": "O73888", "url": "https://www.uniprot.org/uniprotkb/O73888" } ], "pmid": "" }, { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "O73888", "url": "https://www.uniprot.org/uniprotkb/O73888" } ], "pmid": "" }, { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "O73888", "url": "https://www.uniprot.org/uniprotkb/O73888" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "O73888", "url": "https://www.uniprot.org/uniprotkb/O73888" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "O73888", "url": "https://www.uniprot.org/uniprotkb/O73888" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "prostaglandin metabolic process", "id": "GO:0006693", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006693", "evidence": [ { "database": "UniProtKB", "id": "O73888", "url": "https://www.uniprot.org/uniprotkb/O73888" } ], "pmid": "" }, { "name": "prostaglandin biosynthetic process", "id": "GO:0001516", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001516", "evidence": [ { "database": "UniProtKB", "id": "O73888", "url": "https://www.uniprot.org/uniprotkb/O73888" } ], "pmid": "" }, { "name": "glutathione metabolic process", "id": "GO:0006749", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006749", "evidence": [ { "database": "UniProtKB", "id": "O73888", "url": "https://www.uniprot.org/uniprotkb/O73888" } ], "pmid": "" }, { "name": "cyclooxygenase pathway", "id": "GO:0019371", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019371", "evidence": [ { "database": "UniProtKB", "id": "O73888", "url": "https://www.uniprot.org/uniprotkb/O73888" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "10600", "name": "", "equation": "prostaglandin H2 = prostaglandin D2", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q8QFM7-1", "O73888-1" ], "evidence": [ { "id": "10600", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/10600" } ] }, { "id": "16437", "name": "", "equation": "RX + glutathione = an S-substituted glutathione + a halide anion + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P20137-1", "P20135-1", "A0A8V0ZJE0-1", "Q08392-1", "Q08393-1", "A0A8V0Y5A9-1", "A0A8V0YGN2-1", "F1N9G6-1", "A0A8V1AHJ8-1", "O73888-1", "P20136-1", "P26697-1", "E1BUB6-1", "A0A1D5PN41-1" ], "evidence": [ { "id": "16437", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/16437" } ] }, { "id": "51232", "name": "", "equation": "2-glyceryl-prostaglandin H2 = 2-glyceryl-prostaglandin D2", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "O73888-1" ], "evidence": [ { "id": "51232", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/51232" } ] }, { "id": "R-GGA-176054", "name": "GST dimers conjugate GSH with cytosolic substrates", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P20135-1", "Q08393-1", "A0A8V1AI83-1", "A0A8V0ZJE0-1", "A0A8V0XB81-1", "A0A1D5PN41-1", "A0A8V0XH39-1", "E1BUB6-1", "O73888-1", "A0A1D5NT70-1" ], "evidence": [ { "id": "R-GGA-176054", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-176054" } ] }, { "id": "R-GGA-2161701", "name": "PGH2 is isomerised to PGD2 by HPGDS", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [ "R-ALL-879629" ], "enzyme_list": [ "O73888-1" ], "evidence": [ { "id": "R-GGA-2161701", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2161701" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-879629", "participant_name": "PGD2 [cytosol]", "crossref": [ { "id": "ZINC000085994848", "database": "ZINC", "url": "" }, { "id": "C00696", "database": "COMPOUND", "url": "" }, { "id": "57406", "database": "ChEBI", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5NT70", "gene_name": "LOC395611", "activity": [ { "ec_number": "2.5.1.18", "activity": "RX + glutathione = an S-substituted glutathione + a halide anion + H(+).", "evidence": [ { "id": "A0A1D5NT70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NT70" } ] }, { "ec_number": "2.5.1.18", "activity": "", "evidence": [ { "id": "A0A1D5NT70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NT70" } ] } ] }, { "uniprot_ac": "A0A1D5PN41", "gene_name": "GSTZ1", "activity": [ { "ec_number": "5.2.1.2", "activity": "4-maleylacetoacetate = 4-fumarylacetoacetate.", "evidence": [ { "id": "A0A1D5PN41", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PN41" } ] }, { "ec_number": "2.5.1.18", "activity": "RX + glutathione = an S-substituted glutathione + a halide anion + H(+).", "evidence": [ { "id": "A0A1D5PN41", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PN41" } ] }, { "ec_number": "5.2.1.2", "activity": "", "evidence": [ { "id": "A0A1D5PN41", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PN41" } ] }, { "ec_number": "2.5.1.18", "activity": "", "evidence": [ { "id": "A0A1D5PN41", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PN41" } ] } ] }, { "uniprot_ac": "A0A8V0XB81", "gene_name": "GSTA4", "activity": [ { "ec_number": "2.5.1.18", "activity": "RX + glutathione = an S-substituted glutathione + a halide anion + H(+).", "evidence": [ { "id": "A0A8V0XB81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XB81" } ] }, { "ec_number": "2.5.1.18", "activity": "", "evidence": [ { "id": "A0A8V0XB81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XB81" } ] } ] }, { "uniprot_ac": "A0A8V0XH39", "gene_name": "LOC100859645", "activity": [ { "ec_number": "2.5.1.18", "activity": "RX + glutathione = an S-substituted glutathione + a halide anion + H(+).", "evidence": [ { "id": "A0A8V0XH39", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XH39" } ] }, { "ec_number": "2.5.1.18", "activity": "", "evidence": [ { "id": "A0A8V0XH39", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XH39" } ] } ] }, { "uniprot_ac": "A0A8V0Y5A9", "gene_name": "LANCL1", "activity": [ { "ec_number": "2.5.1.18", "activity": "RX + glutathione = an S-substituted glutathione + a halide anion + H(+).", "evidence": [ { "id": "A0A8V0Y5A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5A9" } ] }, { "ec_number": "2.5.1.18", "activity": "", "evidence": [ { "id": "A0A8V0Y5A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5A9" } ] } ] }, { "uniprot_ac": "A0A8V0YGN2", "gene_name": "MGST1", "activity": [ { "ec_number": "2.5.1.18", "activity": "RX + glutathione = an S-substituted glutathione + a halide anion + H(+).", "evidence": [ { "id": "A0A8V0YGN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGN2" } ] }, { "ec_number": "2.5.1.18", "activity": "", "evidence": [ { "id": "A0A8V0YGN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGN2" } ] } ] }, { "uniprot_ac": "A0A8V0ZJE0", "gene_name": "GSTO2", "activity": [ { "ec_number": "1.20.4.2", "activity": "methylarsonate + 2 glutathione + H(+) = methylarsonous acid + glutathione disulfide + H2O.", "evidence": [ { "id": "A0A8V0ZJE0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJE0" } ] }, { "ec_number": "1.8.5.1", "activity": "L-dehydroascorbate + 2 glutathione = glutathione disulfide + L-ascorbate.", "evidence": [ { "id": "A0A8V0ZJE0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJE0" } ] }, { "ec_number": "2.5.1.18", "activity": "RX + glutathione = an S-substituted glutathione + a halide anion + H(+).", "evidence": [ { "id": "A0A8V0ZJE0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJE0" } ] }, { "ec_number": "2.5.1.18", "activity": "", "evidence": [ { "id": "A0A8V0ZJE0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJE0" } ] }, { "ec_number": "1.8.5.1", "activity": "", "evidence": [ { "id": "A0A8V0ZJE0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJE0" } ] }, { "ec_number": "1.20.4.2", "activity": "", "evidence": [ { "id": "A0A8V0ZJE0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJE0" } ] } ] }, { "uniprot_ac": "A0A8V1AHJ8", "gene_name": "GSTM2", "activity": [ { "ec_number": "2.5.1.18", "activity": "RX + glutathione = an S-substituted glutathione + a halide anion + H(+).", "evidence": [ { "id": "A0A8V1AHJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHJ8" } ] }, { "ec_number": "2.5.1.18", "activity": "", "evidence": [ { "id": "A0A8V1AHJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHJ8" } ] } ] }, { "uniprot_ac": "A0A8V1AI83", "gene_name": "LOC107050492", "activity": [ { "ec_number": "2.5.1.18", "activity": "RX + glutathione = an S-substituted glutathione + a halide anion + H(+).", "evidence": [ { "id": "A0A8V1AI83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI83" } ] }, { "ec_number": "2.5.1.18", "activity": "", "evidence": [ { "id": "A0A8V1AI83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI83" } ] } ] }, { "uniprot_ac": "E1BUB6", "gene_name": "GSTT1L", "activity": [ { "ec_number": "2.5.1.18", "activity": "RX + glutathione = an S-substituted glutathione + a halide anion + H(+).", "evidence": [ { "id": "E1BUB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUB6" } ] }, { "ec_number": "2.5.1.18", "activity": "", "evidence": [ { "id": "E1BUB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUB6" } ] } ] }, { "uniprot_ac": "F1N9G6", "gene_name": "GSTK1", "activity": [ { "ec_number": "2.5.1.18", "activity": "RX + glutathione = an S-substituted glutathione + a halide anion + H(+).", "evidence": [ { "id": "F1N9G6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N9G6" } ] }, { "ec_number": "2.5.1.18", "activity": "", "evidence": [ { "id": "F1N9G6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N9G6" } ] } ] }, { "uniprot_ac": "O73888", "gene_name": "HPGDS", "activity": [ { "ec_number": "5.3.99.2", "activity": "prostaglandin H2 = prostaglandin D2.", "evidence": [ { "id": "O73888", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O73888" } ] }, { "ec_number": "2.5.1.18", "activity": "RX + glutathione = an S-substituted glutathione + a halide anion + H(+).", "evidence": [ { "id": "O73888", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O73888" } ] }, { "ec_number": "2.5.1.18", "activity": "", "evidence": [ { "id": "O73888", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O73888" } ] }, { "ec_number": "5.3.99.2", "activity": "", "evidence": [ { "id": "O73888", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O73888" } ] } ] }, { "uniprot_ac": "P20135", "gene_name": "GSTT1", "activity": [ { "ec_number": "2.5.1.18", "activity": "RX + glutathione = an S-substituted glutathione + a halide anion + H(+).", "evidence": [ { "id": "P20135", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P20135" } ] }, { "ec_number": "2.5.1.18", "activity": "", "evidence": [ { "id": "P20135", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P20135" } ] } ] }, { "uniprot_ac": "P20136", "gene_name": "GSTM2", "activity": [ { "ec_number": "2.5.1.18", "activity": "RX + glutathione = an S-substituted glutathione + a halide anion + H(+).", "evidence": [ { "id": "P20136", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P20136" } ] }, { "ec_number": "2.5.1.18", "activity": "", "evidence": [ { "id": "P20136", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P20136" } ] } ] }, { "uniprot_ac": "P20137", "gene_name": "", "activity": [ { "ec_number": "2.5.1.18", "activity": "RX + glutathione = an S-substituted glutathione + a halide anion + H(+).", "evidence": [ { "id": "P20137", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P20137" } ] }, { "ec_number": "2.5.1.18", "activity": "", "evidence": [ { "id": "P20137", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P20137" } ] } ] }, { "uniprot_ac": "P26697", "gene_name": "", "activity": [ { "ec_number": "2.5.1.18", "activity": "RX + glutathione = an S-substituted glutathione + a halide anion + H(+).", "evidence": [ { "id": "P26697", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P26697" } ] }, { "ec_number": "2.5.1.18", "activity": "", "evidence": [ { "id": "P26697", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P26697" } ] } ] }, { "uniprot_ac": "Q08392", "gene_name": "", "activity": [ { "ec_number": "2.5.1.18", "activity": "RX + glutathione = an S-substituted glutathione + a halide anion + H(+).", "evidence": [ { "id": "Q08392", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08392" } ] }, { "ec_number": "2.5.1.18", "activity": "", "evidence": [ { "id": "Q08392", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08392" } ] } ] }, { "uniprot_ac": "Q08393", "gene_name": "", "activity": [ { "ec_number": "2.5.1.18", "activity": "RX + glutathione = an S-substituted glutathione + a halide anion + H(+).", "evidence": [ { "id": "Q08393", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08393" } ] }, { "ec_number": "2.5.1.18", "activity": "", "evidence": [ { "id": "Q08393", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08393" } ] } ] }, { "uniprot_ac": "Q8QFM7", "gene_name": "PTGDS", "activity": [ { "ec_number": "5.3.99.2", "activity": "prostaglandin H2 = prostaglandin D2.", "evidence": [ { "id": "Q8QFM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8QFM7" } ] }, { "ec_number": "5.3.99.2", "activity": "", "evidence": [ { "id": "Q8QFM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8QFM7" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-O73888-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 199, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-O73888-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/O73888" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "5.3.99.2", "ec_name": "prostaglandin H2 = prostaglandin D2.", "evidence": [ { "id": "5.3.99.2", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:5.3.99.2" }, { "id": "5.3.99.2", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=5.3.99.2" } ] }, { "ec_number": "2.5.1.18", "ec_name": "RX + glutathione = an S-substituted glutathione + a halide anion + H(+).", "evidence": [ { "id": "2.5.1.18", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.5.1.18" }, { "id": "2.5.1.18", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.5.1.18" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { 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"o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 4 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "F1NTD3-1", "uniprot_ac": "F1NTD3", "uniprot_id": "F1NTD3_CHICK", "mass": { "chemical_mass": 56776.0, "monoisotopic_mass": 56776.0 }, "refseq": { "ac": "NP_001384808", "name": "bone morphogenetic protein receptor type-1B precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384808" }, "gene_names": [ { "name": "BMPR1B", "type": "recommended", "evidence": [ { "id": "F1NTD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NTD3" } ] }, { "name": "BMPR1B", "type": "synonym", "evidence": [ { "id": "NP_001384808", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384808" } ] }, { "name": "RPK-1", "type": "synonym", "evidence": [ { "id": "NP_001384808", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384808" } ] } ], "protein_names": [ { "name": "receptor protein serine/threonine kinase", "type": "recommended", "evidence": [ { "id": "F1NTD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NTD3/entry#names_and_taxonomy" } ] }, { "name": "2.7.11.30", "type": "synonym", "evidence": [ { "id": "F1NTD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NTD3/entry#names_and_taxonomy" } ] }, { "name": "ALK-6", "type": "synonym", "evidence": [ { "id": "NP_001384808", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384808" } ] }, { "name": "BMP type-1B receptor", "type": "synonym", "evidence": [ { "id": "NP_001384808", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384808" } ] }, { "name": "BMPR-1B", "type": "synonym", "evidence": [ { "id": "NP_001384808", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384808" } ] }, { "name": "SKR6", "type": "synonym", "evidence": [ { "id": "NP_001384808", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384808" } ] }, { "name": "activin receptor-like kinase 6", "type": "synonym", "evidence": [ { "id": "NP_001384808", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384808" } ] }, { "name": "bone morphogenetic protein receptor type-1B precursor", "type": "synonym", "evidence": [ { "id": "NP_001384808", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384808" } ] }, { "name": "bone morphogenetic protein receptor, type IB", "type": "synonym", "evidence": [ { "id": "NP_001384808", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384808" } ] }, { "name": "receptor protein kinase", "type": "synonym", "evidence": [ { "id": "NP_001384808", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384808" } ] }, { "name": "serine/threonine-protein kinase receptor R6", "type": "synonym", "evidence": [ { "id": "NP_001384808", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384808" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR13267659.302163.1, SRR13267660.9165.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992393 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000074.1. On Dec 3, 2021 this sequence version replaced XP_015131638.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.", "evidence": [ { "database": "RefSeq", "id": "NP_001384808", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384808" } ] }, { "annotation": "BMP signaling via Bmpr1a and Bmpr1b, is sufficient to modify nuclear organization in the chick diencephalon", "evidence": [ { "database": "RefSeq", "id": "NP_001384808", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384808" }, { "database": "PubMed", "id": "15804571", "url": "https://glygen.org/publication/PubMed/15804571" } ] }, { "annotation": "The finding that retinal gene expression for BMP2, 4, 7 and their receptors are not affected by short-term optical defocus contrasts with previous observations of sign-dependent expression changes for the same genes in the RPE.", "evidence": [ { "database": "RefSeq", "id": "NP_001384808", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384808" }, { "database": "PubMed", "id": "28359351", "url": "https://glygen.org/publication/PubMed/28359351" } ] }, { "annotation": "Type Ib BMP receptors mediate the rate of commissural axon extension through inhibition of cofilin activity", "evidence": [ { "database": "RefSeq", "id": "NP_001384808", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384808" }, { "database": "PubMed", "id": "23250207", "url": "https://glygen.org/publication/PubMed/23250207" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NTD3", "url": "https://www.uniprot.org/uniprotkb/F1NTD3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "BMPR1B", "url": "https://www.uniprot.org/uniprotkb/F1NTD3", "locus": { "chromosome": "4", "start_pos": 58106237, "end_pos": 57870940, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010004337", "url": "https://www.ensembl.org/id/ENSGALG00010004337" } ] } } ], "crossref": [ { "id": "F1NTD3", "url": "https://alphafold.ebi.ac.uk/entry/F1NTD3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000012216", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000012216", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd14219", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14219", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd23613", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd23613", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "396030", "url": "https://www.ncbi.nlm.nih.gov/gene/396030", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000472", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000472", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001245", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001245", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003605", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003605", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008271", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008271", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017441", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017441", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045860", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045860", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:396030", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:396030", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HSEICGM", "url": "https://omabrowser.org/oma/group/HSEICGM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XM94", "url": "https://www.orthodb.org/?gene=A0A8V0XM94", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XNY4", "url": "https://www.orthodb.org/?gene=A0A8V0XNY4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NTD3", "url": "https://www.orthodb.org/?gene=F1NTD3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23255", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23255", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23255:SF62", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23255:SF62", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01064", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01064", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07714", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07714", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08515", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08515", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-201451", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-201451", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001384808", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384808", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0XM94", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XM94", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XM94-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XM94-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XNY4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNY4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XNY4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNY4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NTD3", "url": "https://www.uniprot.org/uniprotkb/F1NTD3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NTD3-1", "url": "https://www.uniprot.org/uniprotkb/F1NTD3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPLLSSSKLSVESRKEDGEGTAPAPPQKKLSCQCHHHCPEDSVNSTCSTDGYCFTIIEEDDSGGHLVTKGCLGLEGSDFQCRDTPIPHQRRSIECCTGQDYCNKHLHPTLPPLKNRDFAEGNIHHKALLISVTVCSILLVLIIIFCYFRYKRQEARPRYSIGLEQDETYIPPGESLKDLIEQSQSSGSGSGLPLLVQRTIAKQIQMVKQIGKGRYGEVWMGKWRGEKVAVKVFFTTEEASWFRETEIYQTVLMRHENILGFIAADIKGTGSWTQLYLITDYHENGSLYDYLKSTTLDTKGMLKLAYSSVSGLCHLHTEIFSTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVKFISDTNEVDIPPNTRVGTKRYMPPEVLDESLNRNHFQSYIMADMYSFGLILWEIARRCVSGGIVEEYQLPYHDLVPSDPSYEDMREIVCIKRLRPSFPNRWSSDECLRQMGKLMMECWAHNPASRLTALRVKKTLAKMSESQDIKL", "length": 502, "header": "tr|F1NTD3-1|F1NTD3_CHICK Isoform 1 of receptor protein serine/threonine kinase OS=Gallus gallus OX=9031 GN=BMPR1B PE=3 SV=1 CANONICAL=F1NTD3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0XM94-1", "url": "https://www.uniprot.org/uniprotkb/F1NTD3/entry#A0A8V0XM94-1", "sequence": { "sequence": "MVRAQHLPLHRRSCHVSATTIVLRTQSTAPAGLWSTDGYCFTIIEEDDSGGHLVTKGCLGLEGSDFQCRDTPIPHQRRSIECCTGQDYCNKHLHPTLPPLKNRDFAEGNIHHKALLISVTVCSILLVLIIIFCYFRYKRQEARPRYSIGLEQDETYIPPGESLKDLIEQSQSSGSGSGLPLLVQRTIAKQIQMVKQIGKGRYGEVWMGKWRGEKVAVKVFFTTEEASWFRETEIYQTVLMRHENILGFIAADIKGTGSWTQLYLITDYHENGSLYDYLKSTTLDTKGMLKLAYSSVSGLCHLHTEIFSTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVKFISDTNEVDIPPNTRVGTKRYMPPEVLDESLNRNHFQSYIMADMYSFGLILWEIARRCVSGGIVEEYQLPYHDLVPSDPSYEDMREIVCIKRLRPSFPNRWSSDECLRQMGKLMMECWAHNPASRLTALRVKKTLAKMSESQDIKL", "length": 489, "header": "tr|A0A8V0XM94-1|F1NTD3_CHICK Computationally mapped isoform of receptor protein serine/threonine kinase OS=Gallus gallus OX=9031 GN=BMPR1B PE=3 SV=1 CANONICAL=F1NTD3-1" }, "locus": { "chromosome": "4", "start_pos": 58105827, "end_pos": 58077524, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010010123.1", "url": "https://www.ensembl.org/id/ENSGALT00010010123.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010005917.1", "url": "https://www.ensembl.org/id/ENSGALP00010005917.1" } ] } }, { "isoform_ac": "A0A8V0XNY4-1", "url": "https://www.uniprot.org/uniprotkb/F1NTD3/entry#A0A8V0XNY4-1", "sequence": { "sequence": "MLKTVFSSMFFTSEPLTDSFFSILSTDGYCFTIIEEDDSGGHLVTKGCLGLEGSDFQCRDTPIPHQRRSIECCTGQDYCNKHLHPTLPPLKNRDFAEGNIHHKALLISVTVCSILLVLIIIFCYFRYKRQEARPRYSIGLEQDETYIPPGESLKDLIEQSQSSGSGSGLPLLVQRTIAKQIQMVKQIGKGRYGEVWMGKWRGEKVAVKVFFTTEEASWFRETEIYQTVLMRHENILGFIAADIKGTGSWTQLYLITDYHENGSLYDYLKSTTLDTKGMLKLAYSSVSGLCHLHTEIFSTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVKFISDTNEVDIPPNTRVGTKRYMPPEVLDESLNRNHFQSYIMADMYSFGLILWEIARRCVSGGIVEEYQLPYHDLVPSDPSYEDMREIVCIKRLRPSFPNRWSSDECLRQMGKLMMECWAHNPASRLTALRVKKTLAKMSESQDIKL", "length": 479, "header": "tr|A0A8V0XNY4-1|F1NTD3_CHICK Computationally mapped isoform of receptor protein serine/threonine kinase OS=Gallus gallus OX=9031 GN=BMPR1B PE=3 SV=1 CANONICAL=F1NTD3-1" }, "locus": { "chromosome": "4", "start_pos": 58105827, "end_pos": 58086290, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010010108.1", "url": "https://www.ensembl.org/id/ENSGALT00010010108.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010005905.1", "url": "https://www.ensembl.org/id/ENSGALP00010005905.1" } ] } }, { "isoform_ac": "F1NTD3-1", "url": "https://www.uniprot.org/uniprotkb/F1NTD3/entry#F1NTD3-1", "sequence": { "sequence": "MPLLSSSKLSVESRKEDGEGTAPAPPQKKLSCQCHHHCPEDSVNSTCSTDGYCFTIIEEDDSGGHLVTKGCLGLEGSDFQCRDTPIPHQRRSIECCTGQDYCNKHLHPTLPPLKNRDFAEGNIHHKALLISVTVCSILLVLIIIFCYFRYKRQEARPRYSIGLEQDETYIPPGESLKDLIEQSQSSGSGSGLPLLVQRTIAKQIQMVKQIGKGRYGEVWMGKWRGEKVAVKVFFTTEEASWFRETEIYQTVLMRHENILGFIAADIKGTGSWTQLYLITDYHENGSLYDYLKSTTLDTKGMLKLAYSSVSGLCHLHTEIFSTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVKFISDTNEVDIPPNTRVGTKRYMPPEVLDESLNRNHFQSYIMADMYSFGLILWEIARRCVSGGIVEEYQLPYHDLVPSDPSYEDMREIVCIKRLRPSFPNRWSSDECLRQMGKLMMECWAHNPASRLTALRVKKTLAKMSESQDIKL", "length": 502, "header": "tr|F1NTD3-1|F1NTD3_CHICK Isoform 1 of receptor protein serine/threonine kinase OS=Gallus gallus OX=9031 GN=BMPR1B PE=3 SV=1 CANONICAL=F1NTD3-1" }, "locus": { "chromosome": "4", "start_pos": 58105827, "end_pos": 58077475, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010010118.1", "url": "https://www.ensembl.org/id/ENSGALT00010010118.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010005912.1", "url": "https://www.ensembl.org/id/ENSGALP00010005912.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "Altered BMP signaling disrupts chick diencephalic development.", "journal": "Mechanisms of development", "date": "2005-04", "authors": "Lim Youngshin, Cho Ginam, Minarcik Jeremy, Golden Jeffrey", "evidence": [ { "database": "RefSeq", "id": "NP_001384808", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384808" } ], "reference": [ { "type": "PubMed", "id": "15804571", "url": "https://glygen.org/publication/PubMed/15804571" } ] }, { "title": "Type Ib BMP receptors mediate the rate of commissural axon extension through inhibition of cofilin activity.", "journal": "Development (Cambridge, England)", "date": "2013-01-15", "authors": "Yamauchi Ken, Varadarajan Supraja G, Li Joseph E, Butler Samantha J", "evidence": [ { "database": "RefSeq", "id": "NP_001384808", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384808" } ], "reference": [ { "type": "PubMed", "id": "23250207", "url": "https://glygen.org/publication/PubMed/23250207" } ] }, { "title": "Differential gene expression of BMP2 and BMP receptors in chick retina & choroid induced by imposed optical defocus.", "journal": "Visual neuroscience", "date": "2016-01", "authors": "Zhang Yan, Liu Yue, Hang Abraham, Phan Eileen, Wildsoet Christine F", "evidence": [ { "database": "RefSeq", "id": "NP_001384808", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384808" } ], "reference": [ { "type": "PubMed", "id": "28359351", "url": "https://glygen.org/publication/PubMed/28359351" } ] } ], "pathway": [ { "id": "gga:396030", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:396030", "resource": "KEGG Pathway" }, { "id": "R-GGA-201451", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-201451", "resource": "Reactome", "description": "Signaling by BMP" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 7, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "F1NTD3", "url": "https://www.uniprot.org/uniprotkb/F1NTD3" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "F1NTD3", "url": "https://www.uniprot.org/uniprotkb/F1NTD3" } ], "pmid": "" }, { "name": "transmembrane receptor protein serine/threonine kinase activity", "id": "GO:0004675", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004675", "evidence": [ { "database": "UniProtKB", "id": "F1NTD3", "url": "https://www.uniprot.org/uniprotkb/F1NTD3" } ], "pmid": "" }, { "name": "transforming growth factor beta receptor activity, type I", "id": "GO:0005025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005025", "evidence": [ { "database": "UniProtKB", "id": "F1NTD3", "url": "https://www.uniprot.org/uniprotkb/F1NTD3" } ], "pmid": "" }, { "name": "SMAD binding", "id": "GO:0046332", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046332", "evidence": [ { "database": "UniProtKB", "id": "F1NTD3", "url": "https://www.uniprot.org/uniprotkb/F1NTD3" } ], "pmid": "" }, { "name": "BMP receptor activity", "id": "GO:0098821", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098821", "evidence": [ { "database": "UniProtKB", "id": "F1NTD3", "url": "https://www.uniprot.org/uniprotkb/F1NTD3" } ], "pmid": "" }, { "name": "BMP binding", "id": "GO:0036122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036122", "evidence": [ { "database": "UniProtKB", "id": "F1NTD3", "url": "https://www.uniprot.org/uniprotkb/F1NTD3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1NTD3", "url": "https://www.uniprot.org/uniprotkb/F1NTD3" } ], "pmid": "" }, { "name": "receptor complex", "id": "GO:0043235", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043235", "evidence": [ { "database": "UniProtKB", "id": "F1NTD3", "url": "https://www.uniprot.org/uniprotkb/F1NTD3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 17, "go_terms": [ { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "F1NTD3", "url": "https://www.uniprot.org/uniprotkb/F1NTD3" } ], "pmid": "" }, { "name": "tissue development", "id": "GO:0009888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009888", "evidence": [ { "database": "UniProtKB", "id": "F1NTD3", "url": "https://www.uniprot.org/uniprotkb/F1NTD3" } ], "pmid": "" }, { "name": "anatomical structure morphogenesis", "id": "GO:0009653", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009653", "evidence": [ { "database": "UniProtKB", "id": "F1NTD3", "url": "https://www.uniprot.org/uniprotkb/F1NTD3" } ], "pmid": "" }, { "name": "inflammatory response", "id": "GO:0006954", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006954", "evidence": [ { "database": "UniProtKB", "id": "F1NTD3", "url": "https://www.uniprot.org/uniprotkb/F1NTD3" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "F1NTD3", "url": "https://www.uniprot.org/uniprotkb/F1NTD3" } ], "pmid": "" }, { "name": "cellular response to growth factor stimulus", "id": "GO:0071363", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071363", "evidence": [ { "database": "UniProtKB", "id": "F1NTD3", "url": "https://www.uniprot.org/uniprotkb/F1NTD3" } ], "pmid": "" }, { "name": "BMP signaling pathway", "id": "GO:0030509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030509", "evidence": [ { "database": "UniProtKB", "id": "F1NTD3", "url": "https://www.uniprot.org/uniprotkb/F1NTD3" } ], "pmid": "" }, { "name": "positive regulation of bone mineralization", "id": "GO:0030501", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030501", "evidence": [ { "database": "UniProtKB", "id": "F1NTD3", "url": "https://www.uniprot.org/uniprotkb/F1NTD3" } ], "pmid": "" }, { "name": "positive regulation of osteoblast differentiation", "id": "GO:0045669", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045669", "evidence": [ { "database": "UniProtKB", "id": "F1NTD3", "url": "https://www.uniprot.org/uniprotkb/F1NTD3" } ], "pmid": "" }, { "name": "osteoblast differentiation", "id": "GO:0001649", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001649", "evidence": [ { "database": "UniProtKB", "id": "F1NTD3", "url": "https://www.uniprot.org/uniprotkb/F1NTD3" } ], "pmid": "" }, { "name": "dorsal/ventral pattern formation", "id": "GO:0009953", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009953", "evidence": [ { "database": "UniProtKB", "id": "F1NTD3", "url": "https://www.uniprot.org/uniprotkb/F1NTD3" } ], "pmid": "" }, { "name": "chondrocyte development", "id": "GO:0002063", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002063", "evidence": [ { "database": "UniProtKB", "id": "F1NTD3", "url": "https://www.uniprot.org/uniprotkb/F1NTD3" } ], "pmid": "" }, { "name": "proteoglycan biosynthetic process", "id": "GO:0030166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030166", "evidence": [ { "database": "UniProtKB", "id": "F1NTD3", "url": "https://www.uniprot.org/uniprotkb/F1NTD3" } ], "pmid": "" }, { "name": "ovulation cycle", "id": "GO:0042698", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042698", "evidence": [ { "database": "UniProtKB", "id": "F1NTD3", "url": "https://www.uniprot.org/uniprotkb/F1NTD3" } ], "pmid": "" }, { "name": "endochondral bone morphogenesis", "id": "GO:0060350", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060350", "evidence": [ { "database": "UniProtKB", "id": "F1NTD3", "url": "https://www.uniprot.org/uniprotkb/F1NTD3" } ], "pmid": "" }, { "name": "positive regulation of cartilage development", "id": "GO:0061036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061036", "evidence": [ { "database": "UniProtKB", "id": "F1NTD3", "url": "https://www.uniprot.org/uniprotkb/F1NTD3" } ], "pmid": "" }, { "name": "negative regulation of chondrocyte proliferation", "id": "GO:1902731", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902731", "evidence": [ { "database": "UniProtKB", "id": "F1NTD3", "url": "https://www.uniprot.org/uniprotkb/F1NTD3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 284, "end_pos": 286, "annotation": "n_glycosylation_sequon" }, { "start_pos": 343, "end_pos": 345, "annotation": "n_glycosylation_sequon" }, { "start_pos": 44, "end_pos": 46, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-GGA-201443", "name": "Type II receptor phosphorylates type I receptor", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V1A6G4-1", "F1NTD3-1", "F1P3H0-1", "Q90669-1", "Q90670-1" ], "evidence": [ { "id": "R-GGA-201443", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-201443" } ] }, { "id": "R-GGA-201453", "name": "Phospho-R-Smad1/5/8 dissociates from the receptor complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "early endosome", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V1A6G4-1", "F1NTD3-1", "F1P3H0-1", "Q90669-1", "Q90670-1" ], "evidence": [ { "id": "R-GGA-201453", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-201453" } ] }, { "id": "R-GGA-201457", "name": "BMP2 binds to the receptor complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V1A6G4-1", "F1NTD3-1", "F1P3H0-1", "Q90669-1", "Q90670-1" ], "evidence": [ { "id": "R-GGA-201457", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-201457" } ] }, { "id": "R-GGA-201475", "name": "I-Smad competes with R-Smad1/5/8 for type I receptor", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V1A6G4-1", "F1NTD3-1", "F1P3H0-1", "Q90669-1", "Q90670-1" ], "evidence": [ { "id": "R-GGA-201475", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-201475" } ] }, { "id": "R-GGA-201476", "name": "Activated type I receptor phosphorylates R-Smad1/5/8 directly", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V1A6G4-1", "F1NTD3-1", "F1P3H0-1", "Q90669-1", "Q90670-1" ], "evidence": [ { "id": "R-GGA-201476", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-201476" } ] }, { "id": "R-GGA-201648", "name": "An anchoring protein, Endofin, recruits R-Smad1/5/8", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, early endosome membrane, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V1A6G4-1", "F1NTD3-1", "F1P3H0-1", "Q90669-1", "Q90670-1" ], "evidence": [ { "id": "R-GGA-201648", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-201648" } ] }, { "id": "R-GGA-201821", "name": "I-Smad binds to type I receptor, preventing Smad1/5/8 from being activated", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytoplasmic side of plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V1AC55-1", "A0A8V0ZJ49-1", "A0A8V1A6G4-1", "F1NTD3-1", "F1P3H0-1", "Q90669-1", "Q90670-1" ], "evidence": [ { "id": "R-GGA-201821", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-201821" } ] }, { "id": "R-GGA-202604", "name": "Formation of a heteromeric BMP receptor complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V1A6G4-1", "F1NTD3-1", "F1P3H0-1", "Q90669-1", "Q90670-1" ], "evidence": [ { "id": "R-GGA-202604", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-202604" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0ZJ49", "gene_name": "SMURF1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZJ49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ49" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZJ49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ49" } ] } ] }, { "uniprot_ac": "A0A8V1A6G4", "gene_name": "BMPR2", "activity": [ { "ec_number": "2.7.11.30", "activity": "L-seryl-[receptor-protein] + ATP = O-phospho-L-seryl-[receptor-protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A6G4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6G4" } ] }, { "ec_number": "2.7.11.30", "activity": "", "evidence": [ { "id": "A0A8V1A6G4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6G4" } ] } ] }, { "uniprot_ac": "A0A8V1AC55", "gene_name": "SMURF2", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1AC55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC55" } ] }, { "ec_number": "2.3.2.26", "activity": 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"sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "P48143-1", "uniprot_ac": "P48143", "uniprot_id": "VIP_CHICK", "mass": { "chemical_mass": 22540.0, "monoisotopic_mass": 22540.0 }, "refseq": { "ac": "NP_001170780", "name": "VIP peptides isoform 2 preproprotein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001170780" }, "gene_names": [ { "name": "VIP", "type": "recommended", "evidence": [ { "id": "P48143", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48143" } ] }, { "name": "VIP", "type": "synonym", "evidence": [ { "id": "NP_001170780", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001170780" } ] } ], "protein_names": [ { "name": "VIP peptides", "type": "recommended", "evidence": [ { "id": "P48143", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48143/entry#names_and_taxonomy" } ] }, { "name": "VIP peptides isoform 2 preproprotein", "type": "synonym", "evidence": [ { "id": "NP_001170780", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001170780" } ] }, { "name": "VIP peptides", "type": "synonym", "evidence": [ { "id": "NP_001170780", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001170780" } ] }, { "name": "Vasoactive intestinal polypeptide", "type": "synonym", "evidence": [ { "id": "P48143", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48143/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: X80906.1, BU132741.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992440, SAMEA103992453 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000063.1. Transcript Variant: This variant (2) lacks an alternate in-frame exon compared to variant 1. The resulting isoform (2) has the same N- and C-termini but is shorter compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.", "evidence": [ { "database": "RefSeq", "id": "NP_001170780", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001170780" } ] }, { "annotation": "Marker-trait association analyses showed that the 'AGG' indel was associated with total number of eggs from 90 to 300 d of age and total number of qualified eggs from 90 to 300 d of age; C + 338T was associated with duration of broodiness.", "evidence": [ { "database": "RefSeq", "id": "NP_001170780", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001170780" }, { "database": "PubMed", "id": "20461580", "url": "https://glygen.org/publication/PubMed/20461580" } ] }, { "annotation": "PHM-27 is a bioactive form from proteolysis of the same precursor protein, that causes vasodilation.", "evidence": [ { "database": "UniProtKB", "id": "P48143", "url": "https://www.uniprot.org/uniprotkb/P48143#function" }, { "database": "UniProtKB", "id": "P01282", "url": "https://www.uniprot.org/uniprotkb/P01282#function" } ] }, { "annotation": "Study suggests that VIP, Prl, and inhibin have an important effect on the reproductive axis in aging roosters.", "evidence": [ { "database": "RefSeq", "id": "NP_001170780", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001170780" }, { "database": "PubMed", "id": "22184441", "url": "https://glygen.org/publication/PubMed/22184441" } ] }, { "annotation": "VIP is a neuropeptide involved in a diverse array of physiological processes through activating the PACAP subfamily of class B1 G protein-coupled receptors: VIP receptor 1 (VPR1) and VIP receptor 2 (VPR2). Abundantly expressed throughout the CNS and peripheral nervous systems where they primarily exert neuroprotective and immune modulatory roles. Also causes vasodilation, lowers arterial blood pressure, stimulates myocardial contractility, increases glycogenolysis and relaxes the smooth muscle of trachea, stomach and gall bladder.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0XMB1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMB1#function" }, { "database": "UniProtKB", "id": "ARBA00049976", "url": "https://www.uniprot.org/uniprotkb/ARBA00049976#function" }, { "database": "UniProtKB", "id": "P48143", "url": "https://www.uniprot.org/uniprotkb/P48143#function" }, { "database": "UniProtKB", "id": "P01282", "url": "https://www.uniprot.org/uniprotkb/P01282#function" } ] }, { "annotation": "VIP signaling may regulate BMAL1 expression and, thus, a daily rhythmicity within granulosa cells of preovulatory follicles.", "evidence": [ { "database": "RefSeq", "id": "NP_001170780", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001170780" }, { "database": "PubMed", "id": "27021352", "url": "https://glygen.org/publication/PubMed/27021352" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "P48143", "url": "https://www.uniprot.org/uniprotkb/P48143" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "VIP", "url": "https://www.uniprot.org/uniprotkb/P48143", "locus": { "chromosome": "3", "start_pos": 49178149, "end_pos": 49169879, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010005240", "url": "https://www.ensembl.org/id/ENSGALG00010005240" } ] } } ], "crossref": [ { "id": "P48143", "url": "https://alphafold.ebi.ac.uk/entry/P48143", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000013604", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000013604", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "396323", "url": "https://www.ncbi.nlm.nih.gov/gene/396323", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000532", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000532", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046963", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046963", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:396323", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:396323", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PPFSDNY", "url": "https://omabrowser.org/oma/group/PPFSDNY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XMB1", "url": "https://www.orthodb.org/?gene=A0A8V0XMB1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "P48143", "url": "https://www.orthodb.org/?gene=P48143", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11213", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11213", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11213:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11213:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00123", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00123", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:P48143", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:P48143", "database": "PRO", "categories": [ "Protein" ] }, { "id": "R-GGA-418555", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-418555", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-420092", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-420092", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001170780", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001170780", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0XMB1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMB1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XMB1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMB1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P48143", "url": "https://www.uniprot.org/uniprotkb/P48143", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P48143-1", "url": "https://www.uniprot.org/uniprotkb/P48143-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P48143-2", "url": "https://www.uniprot.org/uniprotkb/P48143-2", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEHRGASPLLLALALLSALCWRARALPPRGAAFPAVPRLGNRLPFDAASESDRAHGSLKSESDILQNTLPENEKFYFDLSRIIDRNARHADGIFTSVYSHLLAKLAVKRYLHSLIRKRVSSQDSPVKRHSDAVFTDNYSRFRKQMAVKKYLNSVLTGKRSQEELNPAKLRGEAEILEPSFSENYDDVSVDELLSHLPLDL", "length": 200, "header": "sp|P48143-1|VIP_CHICK Isoform 1 of VIP peptides OS=Gallus gallus OX=9031 GN=VIP PE=1 SV=1 CANONICAL=P48143-1" }, "isoforms": [ { "isoform_ac": "A0A8V0XMB1-1", "url": "https://www.uniprot.org/uniprotkb/P48143/entry#A0A8V0XMB1-1", "sequence": { "sequence": "NAAARRAAQIVRRDGALLFFRLVPIALRSPSSHPDSRSFGSSAAGQGAVPIAQRSALPSSPTDGLAAPLGNRLPFDAASESDRAHGSLKSESDILQNTLPENEKFYFDLSRIIDRNARHADGIFTSVYSHLLAKLAVKRYLHSLIRKRVSSQDSPVKRHSDAVFTDNYSRFRKQMAVKKYLNSVLTGKRSQEELNPAKLRGEAEILEPSFSENYDDVSVDELLSHLPLDL", "length": 230, "header": "tr|A0A8V0XMB1-1|VIP_CHICK Computationally mapped isoform of VIP peptides OS=Gallus gallus OX=9031 GN=VIP PE=1 SV=1 CANONICAL=P48143-1" }, "locus": { "chromosome": "3", "start_pos": 49176353, "end_pos": 49169900, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010012394.1", "url": "https://www.ensembl.org/id/ENSGALT00010012394.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010006958.1", "url": "https://www.ensembl.org/id/ENSGALP00010006958.1" } ] } }, { "isoform_ac": "P48143-1", "url": "https://www.uniprot.org/uniprotkb/P48143/entry#P48143-1", "sequence": { "sequence": "MEHRGASPLLLALALLSALCWRARALPPRGAAFPAVPRLGNRLPFDAASESDRAHGSLKSESDILQNTLPENEKFYFDLSRIIDRNARHADGIFTSVYSHLLAKLAVKRYLHSLIRKRVSSQDSPVKRHSDAVFTDNYSRFRKQMAVKKYLNSVLTGKRSQEELNPAKLRGEAEILEPSFSENYDDVSVDELLSHLPLDL", "length": 200, "header": "sp|P48143-1|VIP_CHICK Isoform 1 of VIP peptides OS=Gallus gallus OX=9031 GN=VIP PE=1 SV=1 CANONICAL=P48143-1" }, "locus": { "chromosome": "3", "start_pos": 49176353, "end_pos": 49170384, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010012401.1", "url": "https://www.ensembl.org/id/ENSGALT00010012401.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010006965.1", "url": "https://www.ensembl.org/id/ENSGALP00010006965.1" } ] } }, { "isoform_ac": "P48143-2", "url": "https://www.uniprot.org/uniprotkb/P48143/entry#P48143-2", "sequence": { "sequence": "MEHRGASPLLLALALLSALCWRARALPPRGAAFPAVPRLGNRLPFDAASESDRAHGSLKSESDILQNTLPENEKFYFDLSRIIDSSQDSPVKRHSDAVFTDNYSRFRKQMAVKKYLNSVLTGKRSQEELNPAKLRGEAEILEPSFSENYDDVSVDELLSHLPLDL", "length": 165, "header": "sp|P48143-2|VIP_CHICK Isoform 2 of VIP peptides OS=Gallus gallus OX=9031 GN=VIP PE=1 SV=1 CANONICAL=P48143-1" }, "locus": { "chromosome": "3", "start_pos": 49176353, "end_pos": 49170384, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010012403.1", "url": "https://www.ensembl.org/id/ENSGALT00010012403.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010006967.1", "url": "https://www.ensembl.org/id/ENSGALP00010006967.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Structure of the vasoactive intestinal octacosapeptide from chicken intestine. The amino acid sequence.", "journal": "FEBS letters", "date": "1975-12-15", "authors": "Nilsson A", "evidence": [ { "database": "UniProtKB", "id": "P48143", "url": "https://www.uniprot.org/uniprotkb/P48143" } ], "reference": [ { "type": "PubMed", "id": "1227973", "url": "https://glygen.org/publication/PubMed/1227973" } ] }, { "title": "Associations between polymorphisms in the chicken VIP gene, egg production and broody traits.", "journal": "British poultry science", "date": "2010-04", "authors": "Zhou M, Du Y, Nie Q, Liang Y, Luo C, Zeng H, Zhang X", "evidence": [ { "database": "RefSeq", "id": "NP_001170780", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001170780" } ], "reference": [ { "type": "PubMed", "id": "20461580", "url": "https://glygen.org/publication/PubMed/20461580" } ] }, { "title": "The effect of active immunization against vasoactive intestinal peptide (VIP) and inhibin on reproductive performance of aging White Leghorn roosters.", "journal": "Poultry science", "date": "2012-01", "authors": "Avital-Cohen N, Heiblum R, Argov N, Rosenstrauch A, Chaiseha Y, Mobarkey N, Rozenboim I", "evidence": [ { "database": "RefSeq", "id": "NP_001170780", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001170780" } ], "reference": [ { "type": "PubMed", "id": "22184441", "url": "https://glygen.org/publication/PubMed/22184441" } ] }, { "title": "Vasoactive intestinal peptide promotes differentiation and clock gene expression in granulosa cells from prehierarchal follicles.", "journal": "Molecular reproduction and development", "date": "2016-05", "authors": "Kim Dongwon, Johnson Alan L", "evidence": [ { "database": "RefSeq", "id": "NP_001170780", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001170780" } ], "reference": [ { "type": "PubMed", "id": "27021352", "url": "https://glygen.org/publication/PubMed/27021352" } ] }, { "title": "Sequence of a cDNA encoding chicken vasoactive intestinal peptide (VIP).", "journal": "Gene", "date": "1995", "authors": "McFarlin D R, Lehn D A, Moran S M, MacDonald M J, Epstein M L", "evidence": [ { "database": "UniProtKB", "id": "P48143", "url": "https://www.uniprot.org/uniprotkb/P48143" } ], "reference": [ { "type": "PubMed", "id": "7890166", "url": "https://glygen.org/publication/PubMed/7890166" } ] } ], "pathway": [ { "id": "gga:396323", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:396323", "resource": "KEGG Pathway" }, { "id": "R-GGA-418555", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-418555", "resource": "Reactome", "description": "G alpha (s) signalling events" }, { "id": "R-GGA-420092", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-420092", "resource": "Reactome", "description": "Glucagon-type ligand receptors" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 8, "go_terms": [ { "name": "epinephrine secretion", "id": "GO:0048242", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048242", "evidence": 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The reference sequence was derived from JAENSK010000074.1. On or before Nov 5, 2021 this sequence version replaced XP_015131802.1, XP_426323.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. 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"https://www.ebi.ac.uk/interpro/entry/IPR001464", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002392", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002392", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018252", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018252", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018502", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018502", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037104", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037104", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:428767", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428767", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LQGNRDP", "url": "https://omabrowser.org/oma/group/LQGNRDP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XMH5", "url": "https://www.orthodb.org/?gene=A0A8V0XMH5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XQ87", "url": "https://www.orthodb.org/?gene=A0A8V0XQ87", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XSJ5", "url": "https://www.orthodb.org/?gene=A0A8V0XSJ5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "P17153", "url": "https://www.orthodb.org/?gene=P17153", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10502", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10502", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10502:SF26", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10502:SF26", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "pdb_00001ala", "url": "https://www.rcsb.org/structure/pdb_00001ala", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00001yii", "url": "https://www.rcsb.org/structure/pdb_00001yii", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00001yj0", "url": "https://www.rcsb.org/structure/pdb_00001yj0", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "1ALA", "url": "https://www.rcsb.org/structure/1ALA", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "1YII", "url": "https://www.rcsb.org/structure/1YII", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "1YJ0", "url": "https://www.rcsb.org/structure/1YJ0", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "PF00191", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00191", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:P17153", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:P17153", "database": "PRO", "categories": [ "Protein" ] }, { "id": "R-GGA-114608", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-114608", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001026709", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026709", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0XMH5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMH5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XMH5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMH5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XQ87", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ87", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XQ87-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ87-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XSJ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XSJ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XSJ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XSJ5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P17153", "url": "https://www.uniprot.org/uniprotkb/P17153", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P17153-1", "url": "https://www.uniprot.org/uniprotkb/P17153-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAKYTRGTVTAFSPFDARADAEALRKAMKGMGTDEETILKILTSRNNAQRQEIASAFKTLFGRDLVDDLKSELTGKFETLMVSLMRPARIFDAHALKHAIKGAGTNEKVLTEILASRTPAEVQNIKQVYMQEYEANLEDKITGETSGHFQRLLVVLLQANRDPDGRVDEALVEKDAQVLFRAGELKWGTDEETFITILGTRSVSHLRRVFDKYMTISGFQIEETIDRETSGDLEKLLLAVVKCIRSVPAYFAETLYYSMKGAGTDDDTLIRVMVSRSEIDLLDIRHEFRKNFAKSLYQMIQKDTSGDYRKALLLLCGGDDE", "length": 321, "header": "sp|P17153-1|ANXA5_CHICK Isoform 1 of Annexin A5 OS=Gallus gallus OX=9031 GN=ANXA5 PE=1 SV=2 CANONICAL=P17153-1" }, "isoforms": [ { "isoform_ac": "A0A8V0XMH5-1", "url": "https://www.uniprot.org/uniprotkb/P17153/entry#A0A8V0XMH5-1", "sequence": { "sequence": "MAKYTRGTVTAFSPFDARADAEALRKAMKGMGTDEETILKILTSRNNAQRQEIASAFKTLFGRDLVDDLKSELTGKFETLMVSLMRPARIFDAHALKHAIKGAGTNEKVLTEILASRTPAEVQNIKQVYMQEYEANLEDKITGETSGHFQRLLVVLLQANRDPDGRVDEALVEKDAQVLFRAGELKWGTDEETFITILGTRSVSHLRRVFDKYMTISGFQIEETIDRETSGDLEKLLLAVVKCIRSVPAYFAETLYYSMKGTVSVGIYKRFGVCRFGTDQFICFFFPPSELPGAGTDDDTLIRVMVSRSEIDLLDIRHEFRKNFAKSLYQMIQKDTSGDYRKALLLLCGGDDE", "length": 353, "header": "tr|A0A8V0XMH5-1|ANXA5_CHICK Computationally mapped isoform of Annexin A5 OS=Gallus gallus OX=9031 GN=ANXA5 PE=1 SV=1 CANONICAL=P17153-1" }, "locus": { "chromosome": "4", "start_pos": 53509833, "end_pos": 53488606, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010012461.1", "url": "https://www.ensembl.org/id/ENSGALT00010012461.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010007025.1", "url": "https://www.ensembl.org/id/ENSGALP00010007025.1" } ] } }, { "isoform_ac": "A0A8V0XQ87-1", "url": "https://www.uniprot.org/uniprotkb/P17153/entry#A0A8V0XQ87-1", "sequence": { "sequence": "MAKYTRGTVTAFSPFDARADAEALRKAMKGMGTDEETILKILTSRNNAQRQEIASAFKTLFGRDLVDDLKSELTGKFETLMVSLMRPARIFDAHALKHAIKGAGTNEKVLTEILASRTPAEVQNIKQVYMQEYEANLEDKITGETSGHFQRLLVVLLQANRDPDGRVDEALVEKDAQVLFRAGELKWGTDEETFITILGTRSVSHLRRVFDKYMTISGFQIEETIDRETSGDLEKLLLAVVKCIRSVPAYFAETLYYSMKGAGTDDDTLIRVMVSRSEIDLLDIRHEFRKNFAKSLYQMIQCMQKSSSWKMSTEHRTQLFASVF", "length": 324, "header": "tr|A0A8V0XQ87-1|ANXA5_CHICK Computationally mapped isoform of Annexin A5 OS=Gallus gallus OX=9031 GN=ANXA5 PE=1 SV=1 CANONICAL=P17153-1" }, "locus": { "chromosome": "4", "start_pos": 53510117, "end_pos": 53488606, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010012463.1", "url": "https://www.ensembl.org/id/ENSGALT00010012463.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010007027.1", "url": "https://www.ensembl.org/id/ENSGALP00010007027.1" } ] } }, { "isoform_ac": "A0A8V0XSJ5-1", "url": "https://www.uniprot.org/uniprotkb/P17153/entry#A0A8V0XSJ5-1", "sequence": { "sequence": "MAKYTRGTVTAFSPFDARADAEALRKAMKGMGTDEETILKILTSRNNAQRQEIASAFKTLFGRDLVDDLKSELTGKFETLMVSLMRPARIFDAHALKHAIKGAGTNEKVLTEILASRTPAEVQNIKQVYMQEYEANLEDKITGETSGHFQRLLVVLLQANRDPDGRVDEALVEKDAQVLFRAGELKWGTDEETFITILGTRSVSHLRRVFDKYMTISGFQIEETIDRETSGDLEKLLLAVVKCIRSVPAYFAETLYYSMKVGIYFSTCRFPSPLAIVLLSTYLSFLFFTANANRVLYQ", "length": 298, "header": "tr|A0A8V0XSJ5-1|ANXA5_CHICK Computationally mapped isoform of Annexin A5 OS=Gallus gallus OX=9031 GN=ANXA5 PE=1 SV=1 CANONICAL=P17153-1" }, "locus": { "chromosome": "4", "start_pos": 53506655, "end_pos": 53488606, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010012460.1", "url": "https://www.ensembl.org/id/ENSGALT00010012460.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010007024.1", "url": "https://www.ensembl.org/id/ENSGALP00010007024.1" } ] } }, { "isoform_ac": "P17153-1", "url": "https://www.uniprot.org/uniprotkb/P17153/entry#P17153-1", "sequence": { "sequence": "MAKYTRGTVTAFSPFDARADAEALRKAMKGMGTDEETILKILTSRNNAQRQEIASAFKTLFGRDLVDDLKSELTGKFETLMVSLMRPARIFDAHALKHAIKGAGTNEKVLTEILASRTPAEVQNIKQVYMQEYEANLEDKITGETSGHFQRLLVVLLQANRDPDGRVDEALVEKDAQVLFRAGELKWGTDEETFITILGTRSVSHLRRVFDKYMTISGFQIEETIDRETSGDLEKLLLAVVKCIRSVPAYFAETLYYSMKGAGTDDDTLIRVMVSRSEIDLLDIRHEFRKNFAKSLYQMIQKDTSGDYRKALLLLCGGDDE", "length": 321, "header": "sp|P17153-1|ANXA5_CHICK Isoform 1 of Annexin A5 OS=Gallus gallus OX=9031 GN=ANXA5 PE=1 SV=2 CANONICAL=P17153-1" }, "locus": { "chromosome": "4", "start_pos": 53509833, "end_pos": 53488606, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010012462.1", "url": "https://www.ensembl.org/id/ENSGALT00010012462.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010007026.1", "url": "https://www.ensembl.org/id/ENSGALP00010007026.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Annexin V/beta5 integrin interactions regulate apoptosis of growth plate chondrocytes.", "journal": "The Journal of biological chemistry", "date": "2006-10-13", "authors": "Wang Wei, Kirsch Thorsten", "evidence": [ { "database": "RefSeq", "id": "NP_001026709", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026709" } ], "reference": [ { "type": "PubMed", "id": "16914549", "url": "https://glygen.org/publication/PubMed/16914549" } ] }, { "title": "Key role of the N-terminus of chicken annexin A5 in vesicle aggregation.", "journal": "Protein science : a publication of the Protein Society", "date": "2009-05", "authors": "Turnay Javier, Guzm\u00e1n-Ar\u00e1nguez Ana, Lecona Emilio, Barrasa Juan I, Olmo Nieves, Lizarbe Ma Antonia", "evidence": [ { "database": "RefSeq", "id": "NP_001026709", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026709" } ], "reference": [ { "type": "PubMed", "id": "19388055", "url": "https://glygen.org/publication/PubMed/19388055" } ] }, { "title": "Matrix vesicle annexins exhibit proteolipid-like properties. Selective partitioning into lipophilic solvents under acidic conditions.", "journal": "J. Biol. Chem.", "date": "1991", "authors": "Genge B R, Wu L N, Adkisson H D, Wuthier R E", "evidence": [ { "database": "UniProtKB", "id": "P17153", "url": "https://www.uniprot.org/uniprotkb/P17153" } ], "reference": [ { "type": "PubMed", "id": "2037607", "url": "https://glygen.org/publication/PubMed/2037607" } ] }, { "title": "Alternative splicing or cloning artefact?", "journal": "Trends Biochem. Sci.", "date": "1989", "authors": "Moss S E, Crumpton M J", "evidence": [ { "database": "UniProtKB", "id": "P17153", "url": "https://www.uniprot.org/uniprotkb/P17153" } ], "reference": [ { "type": "PubMed", "id": "2552626", "url": "https://glygen.org/publication/PubMed/2552626" } ] }, { "title": "The structure of anchorin CII, a collagen binding protein isolated from chondrocyte membrane.", "journal": "J. Biol. Chem.", "date": "1988", "authors": "Pilar Fernandez M, Selmin O, Martin G R, Yamada Y, Pf\u00e4ffle M, Deutzmann R, Mollenhauer J, von der Mark K", "evidence": [ { "database": "UniProtKB", "id": "P17153", "url": "https://www.uniprot.org/uniprotkb/P17153" } ], "reference": [ { "type": "PubMed", "id": "2833522", "url": "https://glygen.org/publication/PubMed/2833522" } ] }, { "title": "Biosynthesis, secretion and extracellular localization of anchorin CII, a collagen-binding protein of the calpactin family.", "journal": "EMBO J.", "date": "1988", "authors": "Pf\u00e4ffle M, Ruggiero F, Hofmann H, Fern\u00e1ndez M P, Selmin O, Yamada Y, Garrone R, von der Mark K", "evidence": [ { "database": "UniProtKB", "id": "P17153", "url": "https://www.uniprot.org/uniprotkb/P17153" } ], "reference": [ { "type": "PubMed", "id": "2847914", "url": "https://glygen.org/publication/PubMed/2847914" } ] }, { "title": "Structure of the gene encoding anchorin CII (chick annexin V).", "journal": "Gene", "date": "1994", "authors": "Fern\u00e1ndez M P, Fern\u00e1ndez M R, Morgan R O", "evidence": [ { "database": "UniProtKB", "id": "P17153", "url": "https://www.uniprot.org/uniprotkb/P17153" } ], "reference": [ { "type": "PubMed", "id": "8163186", "url": "https://glygen.org/publication/PubMed/8163186" } ] }, { "title": "Structure of chicken annexin V at 2.25-A resolution.", "journal": "Biochemistry", "date": "1993", "authors": "Bewley M C, Boustead C M, Walker J H, Waller D A, Huber R", "evidence": [ { "database": "UniProtKB", "id": "P17153", "url": "https://www.uniprot.org/uniprotkb/P17153" } ], "reference": [ { "type": "PubMed", "id": "8471604", "url": "https://glygen.org/publication/PubMed/8471604" } ] }, { "title": "Isolation, characterization and localization of annexin V from chicken liver.", "journal": "Biochem. J.", "date": "1993", "authors": "Boustead C M, Brown R, Walker J H", "evidence": [ { "database": "UniProtKB", "id": "P17153", "url": "https://www.uniprot.org/uniprotkb/P17153" } ], "reference": [ { "type": "PubMed", "id": "8484740", "url": "https://glygen.org/publication/PubMed/8484740" } ] } ], "pathway": [ { "id": "gga:428767", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428767", "resource": "KEGG Pathway" }, { "id": "R-GGA-114608", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-114608", "resource": "Reactome", "description": "Platelet degranulation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1MU33-1", "protein_name": "Annexin", "gene_name": "ANXA5", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAQVLRGTVADFPGFDERADAETLRKAMKGLGTDEESILTLLTSRSNAQRQEIAVAFKTLFGRDLLDDLKSELTGKFEKLIVALMKPSRLYDAYELKHALKGAGTDEKVLTEIIASRTPEELRAIEQVYEEEYGSSLEDDVVGDTSGYYQRMLVVLLQANRDPDARIDEAQVEQDAQALFQAGELKWGTDEEKFITIFGTRSVSHLRRVFDKYMTISGFQIEETIDRETSGNLEQLLLAVVKSIRSIPAYLAETLYYAMKGAGTDDHTLIRVVVSRSEIDLYNIRKEFRKNFGTSLYSMIKGDTSGDYKKALLLLCGGEDD", "length": 321 }, "evidence": [ { "id": "P17153", "url": "https://omabrowser.org/oma/group/P17153/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F2Z5C1-1", "protein_name": "Annexin", "gene_name": "ANXA5", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAQVLRGTVTDFPGFDERADAETLRKAMKGLGTDEESILTLLTSRSNAQRQEIAVAFKTLFGRDLLDDLKSELTGKFEKLIVALMKPSRLYDAYELKHALKGAGTDEKILTEIIASRTPEELRAIKQVYEEEYGSSLEDDVVGDTSGYYQRMLVVLLQANRDPDGRIDEAQVEQDAQALFQAGELKWGTDEEKFITIFGTRSVSHLRRVFDKYMTISGFQIEETIDRETSGNLEQLLLAVVKSIRSIPAYLAETLYYAMKGAGTDDHTLIRVMVSRSEIDLFNIRKEFRKNFATSLYSMIKGDTSGDYKKALLLLCGGEDD", "length": 321 }, "evidence": [ { "id": "P17153", "url": "https://omabrowser.org/oma/group/P17153/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P08758-1", "protein_name": "Annexin A5", "gene_name": "ANXA5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAQVLRGTVTDFPGFDERADAETLRKAMKGLGTDEESILTLLTSRSNAQRQEISAAFKTLFGRDLLDDLKSELTGKFEKLIVALMKPSRLYDAYELKHALKGAGTNEKVLTEIIASRTPEELRAIKQVYEEEYGSSLEDDVVGDTSGYYQRMLVVLLQANRDPDAGIDEAQVEQDAQALFQAGELKWGTDEEKFITIFGTRSVSHLRKVFDKYMTISGFQIEETIDRETSGNLEQLLLAVVKSIRSIPAYLAETLYYAMKGAGTDDHTLIRVMVSRSEIDLFNIRKEFRKNFATSLYSMIKGDTSGDYKKALLLLCGEDD", "length": 320 }, "evidence": [ { "id": "P17153", "url": "https://omabrowser.org/oma/group/P17153/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P14668-1", "protein_name": "Annexin A5", "gene_name": "Anxa5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALRGTVTDFSGFDGRADAEVLRKAMKGLGTDEDSILNLLTARSNAQRQQIAEEFKTLFGRDLVNDMKSELTGKFEKLIVALMKPSRLYDAYELKHALKGAGTDEKVLTEIIASRTPEELRAIKQAYEEEYGSNLEDDVVGDTSGYYQRMLVVLLQANRDPDTAIDDAQVELDAQALFQAGELKWGTDEEKFITILGTRSVSHLRRVFDKYMTISGFQIEETIDRETSGNLENLLLAVVKSIRSIPAYLAETLYYAMKGAGTDDHTLIRVIVSRSEIDLFNIRKEFRKNFATSLYSMIKGDTSGDYKKALLLLCGGEDD", "length": 319 }, "evidence": [ { "id": "P17153", "url": "https://omabrowser.org/oma/group/P17153/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P48036-1", "protein_name": "Annexin A5", "gene_name": "Anxa5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MATRGTVTDFPGFDGRADAEVLRKAMKGLGTDEDSILNLLTSRSNAQRQEIAQEFKTLFGRDLVDDLKSELTGKFEKLIVAMMKPSRLYDAYELKHALKGAGTDEKVLTEIIASRTPEELSAIKQVYEEEYGSNLEDDVVGDTSGYYQRMLVVLLQANRDPDTAIDDAQVELDAQALFQAGELKWGTDEEKFITIFGTRSVSHLRRVFDKYMTISGFQIEETIDRETSGNLEQLLLAVVKSIRSIPAYLAETLYYAMKGAGTDDHTLIRVVVSRSEIDLFNIRKEFRKNFATSLYSMIKGDTSGDYKKALLLLCGGEDD", "length": 319 }, "evidence": [ { "id": "P17153", "url": "https://omabrowser.org/oma/group/P17153/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "calcium channel activity", "id": "GO:0005262", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005262", "evidence": [ { "database": "UniProtKB", "id": "P17153", "url": "https://www.uniprot.org/uniprotkb/P17153" } ], "pmid": "" }, { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "P17153", "url": "https://www.uniprot.org/uniprotkb/P17153" } ], "pmid": "" }, { "name": "calcium-dependent phospholipid binding", "id": "GO:0005544", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005544", "evidence": [ { "database": "UniProtKB", "id": "P17153", "url": "https://www.uniprot.org/uniprotkb/P17153" } ], "pmid": "" }, { "name": "phosphatidylserine binding", "id": "GO:0001786", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001786", "evidence": [ { "database": "UniProtKB", "id": "P17153", "url": "https://www.uniprot.org/uniprotkb/P17153" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P17153", "url": "https://www.uniprot.org/uniprotkb/P17153" } ], "pmid": "" }, { "name": "vesicle", "id": "GO:0031982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031982", "evidence": [ { "database": "UniProtKB", "id": "P17153", "url": "https://www.uniprot.org/uniprotkb/P17153" } ], "pmid": "" }, { "name": "sarcolemma", "id": "GO:0042383", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042383", "evidence": [ { "database": "UniProtKB", "id": "P17153", "url": "https://www.uniprot.org/uniprotkb/P17153" } ], "pmid": "" }, { "name": "calcium channel complex", "id": "GO:0034704", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034704", "evidence": [ { "database": "UniProtKB", "id": "P17153", "url": "https://www.uniprot.org/uniprotkb/P17153" } ], "pmid": "" }, { "name": "vesicle membrane", "id": "GO:0012506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012506", "evidence": [ { "database": "UniProtKB", "id": "P17153", "url": "https://www.uniprot.org/uniprotkb/P17153" } ], "pmid": "" }, { "name": "external side of plasma membrane", "id": "GO:0009897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009897", "evidence": [ { "database": "UniProtKB", "id": "P17153", "url": "https://www.uniprot.org/uniprotkb/P17153" } ], "pmid": "" }, { "name": "endothelial microparticle", "id": "GO:0072563", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072563", "evidence": [ { "database": "UniProtKB", "id": "P17153", "url": "https://www.uniprot.org/uniprotkb/P17153" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { 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"database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292112" } ] }, { "name": "alcohol dehydrogenase 1", "type": "synonym", "evidence": [ { "id": "NP_001292112", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292112" } ] }, { "name": "alcohol dehydrogenase I", "type": "synonym", "evidence": [ { "id": "NP_001292112", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292112" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR12888524.101550.1, SRR12888531.75611.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000074.1. On Feb 27, 2015 this sequence version replaced XP_001234263.3. Sequence Note: This RefSeq record was created from transcript data from different strains because no single transcript from the same strain was available for the full length of the gene. The extent of this transcript is supported by transcript alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001292112", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292112" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "P23991", "url": "https://www.uniprot.org/uniprotkb/P23991" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ADH1", "url": "https://www.uniprot.org/uniprotkb/P23991", "locus": {} } ], "crossref": [ { "id": "P23991", "url": "https://alphafold.ebi.ac.uk/entry/P23991", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd08299", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08299", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "771920", "url": 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"id": "gga:771920", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:771920", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YIFAVEP", "url": "https://omabrowser.org/oma/group/YIFAVEP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XP53", "url": "https://www.orthodb.org/?gene=A0A8V0XP53", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "P23991", "url": "https://www.orthodb.org/?gene=P23991", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR43880", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43880", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR43880:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43880:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00107", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00107", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08240", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08240", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:P23991", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:P23991", "database": "PRO", "categories": [ "Protein" ] }, { "id": "R-GGA-211935", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-211935", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-2161541", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2161541", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5365859", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5365859", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-71384", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-71384", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001292112", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292112", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "10736", "url": "https://www.rhea-db.org/rhea/10736", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "10740", "url": "https://www.rhea-db.org/rhea/10740", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0XP53", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XP53", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XP53-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XP53-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P23991", "url": "https://www.uniprot.org/uniprotkb/P23991", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P23991-1", "url": "https://www.uniprot.org/uniprotkb/P23991-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSTVGKVIKCKAAVLWEANKPFSLEEVEVAPPKAHEVRIKIVATGICRSDDHVVTGALAMPFPIILGHEAAGVIESVGEKVTSLKPGDAVIPLFVPQCGECRSCLSTKGNLCIKNDLSSSPTGLMADGTTRFTCKGKAIHHFVGTSTFTEYTVVHETAAAKIDSAAPLEKVCLIGCGFSTGYGAVLQTAKVEAGSTCAVFGLGGVGLSVVMGCKAAGASRIIAVDINKDKFAKAKELGATECINPKDFKKPIHEVLTEMTGQGVDYSFEVIGRIETMTAALASCHNNYGVSVIVGVPPAAQKISFDPMLIFSGRTWKGSVFGGWKSKDAVPKLVADYMKKKFVLDPLITHTLPFTKINEGFDLLRTGKSIRSVLVL", "length": 376, "header": "sp|P23991-1|ADH1_CHICK Isoform 1 of Alcohol dehydrogenase 1 OS=Gallus gallus OX=9031 GN=ADH1 PE=1 SV=2 CANONICAL=P23991-1" }, "isoforms": [ { "isoform_ac": "A0A8V0XP53-1", "url": "https://www.uniprot.org/uniprotkb/P23991/entry#A0A8V0XP53-1", "sequence": { "sequence": "MIFLLCKRVCFYSLLFLAATTCKVIKCKAAVLWEANKPFSLEEVEVAPPKAHEVRIKIVATGICRSDDHVVTGALAMPFPIILGHEAAGVIESVGEKVTSLKPGDAVIPLFVPQCGECRSCLSTKGNLCIKNDLSSSPTGLMADGTTRFTCKGKAIHHFVGTSTFTEYTVVHETAAAKIDSAAPLEKVCLIGCGFSTGYGAVLQTAKVEAGSTCAVFGLGGVGLSVVMGCKAAGASRIIAVDINKDKFAKAKELGATECINPKDFKKPIHEVLTEMTGQGVDYSFEVIGRIETMTAALASCHNNYGVSVIVGVPPAAQKISFDPMLIFSGRTWKGSVFGGWKSKDAVPKLVADYMKKKFVLDPLITHTLPFTKINEGFDLLRTGKSIRSVLVL", "length": 393, "header": "tr|A0A8V0XP53-1|ADH1_CHICK Computationally mapped isoform of Alcohol dehydrogenase 1 OS=Gallus gallus OX=9031 GN=ADH1 PE=1 SV=1 CANONICAL=P23991-1" }, "locus": { "chromosome": "4", "start_pos": 59506992, "end_pos": 59498358, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010014446.1", "url": "https://www.ensembl.org/id/ENSGALT00010014446.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010008478.1", "url": "https://www.ensembl.org/id/ENSGALP00010008478.1" } ] } }, { "isoform_ac": "P23991-1", "url": "https://www.uniprot.org/uniprotkb/P23991/entry#P23991-1", "sequence": { "sequence": "MSTVGKVIKCKAAVLWEANKPFSLEEVEVAPPKAHEVRIKIVATGICRSDDHVVTGALAMPFPIILGHEAAGVIESVGEKVTSLKPGDAVIPLFVPQCGECRSCLSTKGNLCIKNDLSSSPTGLMADGTTRFTCKGKAIHHFVGTSTFTEYTVVHETAAAKIDSAAPLEKVCLIGCGFSTGYGAVLQTAKVEAGSTCAVFGLGGVGLSVVMGCKAAGASRIIAVDINKDKFAKAKELGATECINPKDFKKPIHEVLTEMTGQGVDYSFEVIGRIETMTAALASCHNNYGVSVIVGVPPAAQKISFDPMLIFSGRTWKGSVFGGWKSKDAVPKLVADYMKKKFVLDPLITHTLPFTKINEGFDLLRTGKSIRSVLVL", "length": 376, "header": "sp|P23991-1|ADH1_CHICK Isoform 1 of Alcohol dehydrogenase 1 OS=Gallus gallus OX=9031 GN=ADH1 PE=1 SV=2 CANONICAL=P23991-1" }, "locus": { "chromosome": "4", "start_pos": 59507648, "end_pos": 59498358, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010014452.1", "url": "https://www.ensembl.org/id/ENSGALT00010014452.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010008482.1", "url": "https://www.ensembl.org/id/ENSGALP00010008482.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "Avian alcohol dehydrogenase: the chicken liver enzyme. Primary structure, cDNA-cloning, and relationships to other alcohol dehydrogenases.", "journal": "Eur. J. Biochem.", "date": "1990", "authors": "Estonius M, Karlsson C, Fox E A, H\u00f6\u00f6g J O, Holmquist B, Vallee B L, Davidson W S, J\u00f6rnvall H", "evidence": [ { "database": "UniProtKB", "id": "P23991", "url": "https://www.uniprot.org/uniprotkb/P23991" } ], "reference": [ { "type": "PubMed", "id": "2269284", "url": "https://glygen.org/publication/PubMed/2269284" } ] }, { "title": "Fast atom bombardment mass spectrometry and chemical analysis in determinations of acyl-blocked protein structures.", "journal": "FEBS letters", "date": "1990-08-20", "authors": "Egestad B, Estonius M, Danielsson O, Persson B, Cederlund E, Kaiser R, Holmquist B, Vallee B, Par\u00e9s X, Jefferey J", "evidence": [ { "database": "UniProtKB", "id": "P23991", "url": "https://www.uniprot.org/uniprotkb/P23991" } ], "reference": [ { "type": "PubMed", "id": "2387402", "url": "https://glygen.org/publication/PubMed/2387402" } ] } ], "pathway": [ { "id": "gga:771920", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:771920", "resource": "KEGG Pathway" }, { "id": "R-GGA-211935", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-211935", "resource": "Reactome", "description": "Fatty acids" }, { "id": "R-GGA-2161541", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2161541", "resource": "Reactome", "description": "Abacavir metabolism" }, { "id": "R-GGA-5365859", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5365859", "resource": "Reactome", "description": "RA biosynthesis pathway" }, { "id": "R-GGA-71384", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-71384", "resource": "Reactome", "description": "Ethanol oxidation" } ], "orthologs": [ { "uniprot_canonical_ac": "P00326-1", "protein_name": "Alcohol dehydrogenase 1C", "gene_name": "ADH1C", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-ALL-2161185" ], "output_participant_list": [ "R-ALL-2162081" ], "enzyme_list": [ "P23991-1" ], "evidence": [ { "id": "R-GGA-2162078", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2162078" } ] }, { "id": "R-GGA-5362564", "name": "ADH1A,1C,4 oxidise atROL to atRAL in vitro", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P23991-1" ], "evidence": [ { "id": "R-GGA-5362564", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5362564" } ] }, { "id": "R-GGA-71707", "name": "ethanol + NAD+ => acetaldehyde + NADH + H+", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-ALL-30203" ], "output_participant_list": [ "R-ALL-29510" ], "enzyme_list": [ "P23991-1" ], "evidence": [ { "id": "R-GGA-71707", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-71707" } ] }, { "id": "R-GGA-9971258", "name": "ADH7 dehydrogenates 10-OH-DECA", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. 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